>albocrusta ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TTYAAYAARGTNACNGTNYTNYTNACNGCNTTYATHACNATHGARMGNTGYATHTGYGTN GTNACNCCNYTNAARGTNAARTCNATHYTNACNCCNACNMGNGTNAARTCNATHGTNATH ATGTGYTAYATHGCNGTNGGNATHACNATGGGNCAYGCNTAYTAYYTNCARAAYYTNMGN TGGATGTTYATHCCNACNTAYYTNTCNATGTAYGTNGAYCCNTCNTTYCARTTYATHYTN ATHATHTTYGCNACNYTNTTYYTNGCNAARAGYYTNACNAARTCNGTNAARTGGAARAAR ---------AARATGAAYGAYTCNTCNTCNTCNTCNATHACNAARGARMGNAARGTNGTN MGNYTNGTNTTYGCNATHGCNGTNGTNTTYTGYYTNTTYTCNYTNCCNACNGCNATGGTN TCNYTNATGTAYGCNYTNGTNGAYAGYTTYAARTTYGGNGGNAARGAYGARACNGTNTTY GGNGTNTTYGCNCARATGGCNACNATHGCNATGGGNYTNAAYTCNGGNATHAAYYTNTTY ATHTAYTAYCARAAYAGYTCNAGYTTYAARMGNGCNTTYGAYCARACNTTY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNTTYCARTCNGAYGCNYTNYTNGTNCCNAARCAYTGYGAR TTYGAYCAYAGYGCNGAYATHAGYCARTGYMGNGARTTYTCNCAYTGGAAYAGYGTNGCN GARGAYAARTGYYTNAARAARGGNATGCAYYTNGARTCNTTYGGNATGYTNYTNTAYTGY AARCCNYTNGGNCAYTTYAAYGGNGTNGARTAYGTNTGYTGYCCNAAYCCNTCNGAYACN MGNATHCAY------CCNGARCCNAARGAYGAYGAYAARCCNGAYAGYTGG--------- ------------GARGAYGAYGARGARGAYGAYGARGAYGARGAYAGYGAY--------- ------------GARAGYGAYGARGAYAARGAYTCNGARGCNGTNGAYGAYGARGAYAGY GCN---------------------------------------GAYGTNTAYGARGCNTAY YTNMGNGGNYTNCCNYTNCCNGAYATHTAYATHAAYGARCAYCARCARTAYYTNGCNGCN AARGCNMGNATGATHGTNGTNCARAARAARAARGARTCNAARYTNYTNGAYCARTTYGAR GARTCNCARAARGARATGGAYAARGTNMGNAARACNGAYCCNAARGCNGCNAAYAARATG AAYGAYGARATHGCNACNMGNTTYAARCAYYTNTAYGARTCNTTYAARCARGARGAYGCN GCNGARMGNYTNCARYTNGCNGCNYTNCAYCARMGNMGNGTNYTNGCNAAYYTNAAYGAR MGNAARMGNGARGCNATGGAYAARTAYYTNCARTCNYTNGARGAYGARAAYGTNCCNCAY GTNATGAARTAYYTNAAYAAYTAYATHAARGCNGTNGARAARGAYMGNYTNCAYACNGTN AAYCAYTTYGARCAYYTNAARATHTCNGAYCCNAARGARGCNYTNMGNGTNCAYCCNCAY YTNATHMGNCAYYTNAARYTNACNGARATGMGNATHGAYCARGCNATGGARATGYTNACN CAYTAYCCNGARGTNGARMGNTCNGTNMGNCCNGARATHGARGAYTTYYTNAARAGYTTY AAYGAYATHGCNGAYMGNATHAARAARGTNGTNYTNCCNGTNCCNGTNGTNCCNGARGAY TCNTAYAGYCARGAYCARTCNCARAGYCARTCNGCNTCNGARTCNGARTCNGCNTCNACN TCNGARGAYMGNACNAGYGARGAY------------------AGYAGYTAYAAYTCNGGN ATHATH---------------------------------------GAY------------ ---------------------------GAYGARGTNCARGARAAYGARCAYAGYTAYGAR GARCAYCAYTTYGARGCNAAYGCNMGNGCNGAYACNCAYAGYGTNCARCAYAAYTCNGTN AGYAGYAGYAGYTCNTCNAGYGGNGGNYTNGGNAGYACNGTNGGNATHGTNYTNGGNGCN ATHAGYGTNATGGTNATHGTNGTNGTNGCNGTNGTNATGGTNMGNCAYAAYAARAAYMGN CARCCNGTNTCNCAYGGNTAYGTNGARGTNGAYCCNTCNGCNTCNCCNGARGAYMGNTAY YTNGCNAAYATGCARATGAAYGGNTAYGARAAYCCNACNTAYAARTAYTTYGARGAYCCN CCNAARGAYAARYTNTAYMGNCARGTNACNGTNGARGTNAARGGNCAYGAYCCNGCNGTN ATHAAYAGYTAYCARAARTTYACNACNATGGCNGCNGARCARYTNGGNATHACNATHGCN AGYATHTCNGARCCNCCNAARGTNATHACNMGNAARAGYYTNYTNAARTCNGTNTTYATH TTYAARAARCAYCARCAYCARTAYGARCARMGNACNYTNTTYMGNGTNTTYGARTTYAAR CAYYTNACNGARTCNACNGCNYTNACNTTYYTNGARTAYATHCARMGNAAYYTNCCNGAR GGNATGGCNATGAARGTNACNAARMGNGARYTNCARCCNATHCCNGAYCAYYTNMGNCCN CCNGARCARTCNMGNYTNGGNACNGARGCNTCNAGYGAYTAYTTYAAYGTNATGYTNGGN TCNCARYTNYTNTAYAARTTYGARMGNCCNCARTAYAGYGARATHGTNCARGARCAYCCN GAYAARCCNATGTCNAGYATHTAYGGNGCNACNCAYYTNYTNMGNYTNTTYGTNMGNYTN GGNGCNATGYTNGCNTAYACNACNYTNGAYGARMGNACNGTNCAYATHYTNYTNAAYCAY GTNCAYGAYTTYYTNAARTAYATGTCNAARAAYGGNTCNAAYTTYTTYAARACNTCNAAY TAYGARATHGCNACNCCNGAYTAYCAYMGNAARGCNATH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ACNAARCARMGNTGGATHCCNYTNGAR TCNAAYCCNACNGTNYTNAAYAARTAYGTNCAYAAYYTNGGNATGGAYAARGGNTGGAAY TTYGTNGAYGTNTTYGGNYTNGAYCCNGAYYTNYTNGCNATGGTNCCNMGNCCNGTNGCN GCNGTNGTNYTNYTNTTYCCNGAYACNGAYAAY------------GAYGARGARAGYGGN GARYTNATGAARGAYYTNCCNGAYGAYYTNTAYTAYACNAARCARACNATHGGNAAYGCN TGYGGNACNGTNGCNATHGTNCAYGCNYTNGCNAAYAAYGCNTCNMGNATHGGNTTYGAY GCNGARAARCAYTTYTGYACNTTYYTNTCNTCNACNAARTCNYTNAGYCCNGARGAYAAR GCNAARCAYYTNGARGARGAYYTNCARATGGGNTCNGCNCAYGARGARAGYGCNCARGAR GGNGAYACNGCNGCNCCNGCNGCNTCNGARAARGTNAARTGYCAYTTYATHGCNTTYGTN AAYTTYAAYGGNTCNYTNGTNGARYTNGAYGGNNNNAARNNNNNNCCNGTNACNCAYGGN NNNACNAARGARGAYTCNTTYATHGARGAYNNNGCNGTNGTNATHAARAARTTYATNNNN MGNTGYCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TAYCCNGAYGAYATGYTNGGNTAYGAYYTNGTNGCNCAR GARGAYCCNAAYCAYACNYTNYTNTAYTAYATHAARCARYTNYTNTAYGCNGGNCARYTN AARCCNCCNTTYGAYYTNCCNTTYTTYTTYCAYGCNGCNGARACNAAYTGGCARGGNACN GGNACNGAYGAYAAYYTNATHGAYGCNATHATHYTNAAYACNACNMGNATHGGNCAYGGN TAYGGNYTNAGYAARCAYCCNACNYTNGTNAARGARATHAARGCNMGNGAYATHGCNATH GARGCNAAYCCNATHTCNAAYCARYTNYTNGGNYTNTAYAARGAYCCNMGNAAYCAYGCN YTNGTNCCNYTNATGGCNGAYGAYTTYCCNATHGTNGTNAGYTCNGAYGAYCCNGTNGTN TGGGARGCNGCNCCNYTNTCNAGYGAYTTYTAYATHGCNTTYATGAAYATGTGYGGNGAR AAYAAYTGYYTNMGNTTYYTNAARCARYTNGCNATGAAYTCNTTYAARTAYAGYGGNATG TCNGAYGTNGARAARAGYAARGCNYTNAARYTNTGGCARAARAARTGGGAYGARTTYATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TGY CCNGGNTGGAGYGAYTGYCCNYTNMGNGCNCARAGYACNTTYTGGGCNGCNGCNTCNACN CAYTTYGCNGCNGCNGCNAGYGGNGAYGTNTAYGTNATGYTNGAYGGNTCNGAYGTNAAR GCNTAYMGNAAYGAYAGYTTYTTYMGNCARTAYGARYTNCCNAAYYTNAAYTCNAARGTN TCNTCNGTNAAYGTNYTNYTNATHCAYCAYYTNGAYAARCCNMGNYTNGARACNTGYAAR ACNGGNAGYYTNGTNACNATGAARGCNGAYGTNGARAGYMGNGGNYTNATHTTYAARTGY GARGAYGAYCCNGARGCNATHATGTTYYTNYTNTGYTCNGAYGAYCCNGAYAAYTCNCAR TGYAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CAYAARGGNMGNAAYAAY CAYYTNNNNAARGCNGARAARGCNTTYGCNAAYGAYAGYTCNYTNCARCCNGARACNAAR GCNATHATGMGNTGGYTNACNAGYATHGGNTTYGTNYTNTCNGCNAAYYTNCAYGGNGGN GAYGTNAARGCNAAYTAYCCNTAYGAYGARACNMGNTCNGGNAARATGCARGARTAYACN GCNTGYCCNGAYGAYCAYACNTTYGTNTTYYTNGCNAARTCNTAYGCNGARGCNCAYMGN ACNATGGCNGAYCCNGCNMGNGTNCCNTGYGAYAARGAYGGNGAYAAYAARCCNATHACN AAYGGNGGNATGTGGTAYTCNGTNGCNAARGGNATGCARGAYTAYAAYTAYYTNAAYACN AAYTGYTTYGARATHACNYTNGARYTNGGNTGYGAYAARTTYCCNCCNCCNTCNGARYTN GARCARTTYTGGGTNGAYAAYGTNGGNGCNYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATGGCNGAYYTNATHCAYAARATHTTYGGNCCNAAR CAYGGNAARAGYGCNGAYCAYGGNAARCARTCNACNGARCCNGARGGNTAYACNAARCAR CARCAYGARTTYTTYAARGARTTYYTNGCN------------------------------ ------------------------------------------------------------ ---------------------------------------------CCNATHCAYTGYTGG ATGCCNGCNGARTAYAGYAARAARCARTTYMGNAARTAYTCNGARAGYTAYTGYTGGATH CAYCCNATGTAYAAYATHCCNATGGAYGAYTCNATHCCNTTYCARCAYGARGAYMGNTGG TAYAAYGAYYTNGGNTAYTAYMGNTGGGTNTTYATHATGTTYYTNATHCARGCNTTYTTY TTYAARYTNCCNAAYGTNTGYTGGACNGARYTNAARAAYTAYTCNGGNYTNAAYGTNTCN AARGTNGTNGCNATGGCNTGGGARACNTCNATGATGACNCARGARAARMGNGAYGARACN ATGGAYCAYATHGCNATHTTYATHGAYMGNTGGYTNAARACNTAYTCNCAYTAYAARTTY AGYGCNATHACNCARTTYMGNGAYAARTTYTCNAGYATHATHTTYTGYTTYGGNMGNAAR ACNGGNAAYTAYYTNAGYGGNYTNTAYYTNTTYACNAARTTYATGTAYTTYGCNAAYATH ATHGGNCARTTYTTYYTNGTNTCNAARTTYYTNGAYYTNGAYTTYTGGGGNTTYGGNTTY CARGCNYTNAGYGTNTTYMGNAARAARGGNAARTGGGARGAYCAYTAYAAYTTYCCNMGN ATHGGNTAYTGYGAYTAYAARATHMGNCARYTNGARAAYMGNYTNCCNTTYACNGTNCAR TGYGTNYTNTCNATHAAYATGTTYYTNGARAARATGTAYYTNATHYTNTGGTTYTGGATG ATGATGATGYTNGTNTTYAAYATHATHAAYYTNACNCARTGGYTNTAYMGNGCNYTNYTN CCNAAYACNGGNMGNACNTTYATHCARAARTAYYTNAARYTNYTNGGNATHGAYAARAAR TCNAAYAARAARYTNTTYGTNAARTTYGCNMGNAAYTAYYTNMGNACNGAYGGNGTNTTY ATGYTNMGNATHGTNGCNACNAAYACNAGYGARATHYTNACNACNGAYYTNGTNAARCAY YTNTGGAAYAARTTYAARGARMGNCAYGGNGTNGTNGARGARGTNCCNGCNGGNACNAAY GGNGGNGTNCCNTCNGTNCCNTCNGCNCCNCARGTNCARGAYAAYGAYGAYGAYYTNCCN ------------------------------------------------------------ ------TCNATHCCNACNMGNTCNGCNGARGAYACNYTNCARGAYGCNTCNTCNYTNGTN YTNGAYAARMGNCCNAARTAYATGGAYACNMGNMGNGAYYTNGAYATHTTYAARGAYYTN GTNYTNATGAGYYTNCARGARYTNGTNGAYGARGGNMGNYTNGARTCNTCNATHYTNCCN GARGAR------GAYMGNGARACNAGYAARCCNGTNGARAARMGNMGNTAYATGGGNYTN TGYATGCAYMGNCARGCNAAYCARTAYATHCCNTTYCCNTGYYTNMGNACNGGNMGNATG AARGCNACNYTNTGYATHTGYYTNGTNYTNTTYGCNACNGTNTTYGCNGAYAAYTAYYTN TGY---CCNAARGAYGGNGGNATHTTYGAYTGYTAYGARTAYGCNAARACNMGNMGNAGY TGYYTNACNGAYGCNMGN------MGNACNGTNGTNGTNTGYGGNTTYTGYCCNAARAAR TGGGARTTYTGYGTNACNMGNGGNAARYTNGARAARTCNAARMGNCCNGARGARGAYTGY GGNGCNGAYTAYGARTCNACNCCNTGYACNGCNAARAAYTCNTAY--------------- ---------------------------GCNGAYGGNTTYGCNTTYTAYMGNGGNGAYATH CCNAAYGGNTTYAAYGTNGCNGAYCCNTGYCAYCCNGGNAARACNATHGCNGGNGTNGGN CAYGTNAGYCCNATHGGNGGNGGNCCNAAYAAYCARTTYGGNGTNGAYTTYMGNTAYGCN GGNCAYYTNTGGACNAARACNYTNTGYAARCARGAYTCNGAYGGNGAYGGNGTNGCNAAY GGNGARGARYTNGGNGAYCCNGAYTGYGTNTGGAARYTNGGNGAYATHCCNGCNMGNACN ACNGAYATHACNCAYCCNGGNATHGAYAAYGAYAAYCCNGGNTGY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ACNYTNATHATH ATHTCNTCNTAYACNGCNAAYYTNGCNGCNTTYYTNACNATHGARAARYTNGTNGCNCCN ATHAAYTCNGCNGAYGAYYTNGTNAAYCAYAARTCNATHAARTAYGGNACNAARCARACN GGNACNTCNTGGMGNTTYTTYGARCAYTCNACNATHGAYACNTAYATHACNATGAARAAR TTYATGYTNGARAAYGARCARGARGTNYTNTTYAAYAAYTAYGAYGARGGNGTNATHAAR GTNMGNGARTCNAARGGNGAYTAYGCNTTYYTNYTNGARTCNGCNATGAAYTCNTAYCAY GCNCARCARGARCCNTGYGAYACNATGATGGTNGGNGAYCCNYTNGAYAAYAARGGNTAY GGNGTNGCNACNTAYATHGAYTAYCCNYTNMGNCAYAAYATHAAYATHGCNGTNYTNACN YTNGARGARAARGGNGARYTNATHAARYTNCARCARAARTGGTGGYTNGAYAARGGNCAR TGYGGNGCNCARAAYTCNGGNAARGARTCNACNGGNACNCARAGYGCNYTNACNYTNAGY AAYGTNTCNGGNATHTTYATHYTNACNTTYTGYTTYATHGCNGGNACNTCNAGYGGNGTN TTYTAYATHCCNGGNTCNGTNGTNAGYTAYCCNAARATGGGNAARMGNGCNTTYTAYACN AAYGCNACNGGNAAYMGNTAYCCNATGATGGGNMGNMGNTCNTCNTCNGAYGCNAAY--- ---------------------AGYCARGGNTCNATGGGNCARCARGCNGARGCNGTNGTN CCNGARGTNAARMGNGGNGTNTTYACNCARGGNCCNCAYMGNAGYTTYCCNMGNGTNGGN MGNTCNGGNCCNGGNATHGARCCNTCNAGYGCNTCNCARGAYGGNAARATHMGNAGYGAR ATHYTNAARAGYYTNGCNGARMGNYTNGARGGNAGYGAYGTNACNAAYYTNYTNGARGGN TTYCARGARCARGGNGARGCNAGYAAYAARATHCARYTNACNCARTTYYTNTTYYTNATH TTYGAYGARAAYGGNGAYAAYCARYTNAAYAARGARGARTTYATHAGYGGNYTNTCNMGN GTNGTNGARGARAAYYTNYTNTGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AAYGGNGARTAYTTYTAYAARYTNTCNTCNMGNMGNATGMGNTCNAARGARGTNCAR GTNATHCCNTGGGTNGTNTCNGAYAGYAARTAYTCNTTYCARCCNACNCARMGNYTNGAY TCNAAYMGNACNGTNTTYGTNGGNGCNYTNCAYGGNATGYTNACNGCNGARGCNYTNGGN GTNATHATGGGNGAYYTNTTYGGNAAYGTNGTNGARGCNGGNATHGAYACNGAYAARCAY MGNTAYCCNATHGGNTCNGGNMGNGTNACNTTYAGYAGYMGNAARAGYTAYATGAARGCN ATHCARGCNGCNTTYATHGARATHAARACNACNAARTTYACNAARAARYTNTGYMGNGAY YTNATGTGYTTYAARTAYTTYTGYMGNTCNTGYTGGTAYTGGCARCAYGCNCCNGARGCN ATGMGNCAYCAYMGNACNYTNACNMGNAAYACNAARAAYACN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYTTYGGNAARTTYATHACNAARMGN ---TCNGCNAAYGTNCARAARMGN---YTNTCNGAYATHAGYTTYAGYAARCCNCARGCN TTYTCNTAYYTNACNAARMGNMGNACNGARCARAAYGTNGTNTGYGARTGYTGYGTNAAY CARTGYACNTTYACNGARATGTAYCARTAYTGYGCNYTNCCNAGYMGNTAYGGNCCNMGN TTYGTNGGNAARMGNTAYTCNCCNMGNTTYGTNGGNAARMGNTAYGGNCCNMGNTTYGTN GGNAARMGNTAYGGNCCNMGNTTYGTNGGNAARMGNTAYGGNCCNMGNTTYGTNGGNAAR MGNTAY------------------------------------------------------ AGYCCNMGNTTYGTNGGNAARMGNGARGAYGARAAYGARGAYATHAGYAAYTCNCAYATH ATHAARAAR---------------------------GARGAYGAYACNGAYMGNYTNGAY GARMGNCCNGTNTAYTTYGAYGAYGAYTAYGAYAARGAYGAYGARTCNTTYYTNGAYAAR MGNAAYGCNCCNMGNTTYGTNGGNAARMGNACNGCNCCNMGNTTYGTNGGNAARMGNTTY GCNCCNMGNTTYGTNGGNAARMGNTTYGCN------GTNTTYGGNAARMGNCARGCNCCN MGNTTYGTNGGNAARMGNGAY------AAYGCNTTYGAYGCN------------------ YTNGAYTTYYTNMGNTAYAGYYTNGARAAYMGNACNAGYAARMGNCARGCNCCNMGNTTY GTNGGNAARMGNAAYGGN------------GARMGNGTNTAYMGNGAYYTNYTNGAYATG TAYGCNMGNAAYGARGCNATHAAYAARATGMGNGCNAAYGAYAARMGNTGGAGYACNCCN GTNACNCCNAGYTTYATHGGNAARMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ACNYTNGAYGAYGTNCARAARAAYGTNGTNAGYACNTTYTTY GARCCNATHTAYGCNMGNAARGCNTTYCCNTGYYTNGAYGARCCNGCNATGAARGCNACN TTYACNATGAARYTNGCNMGNAARACNAAYCARYTNGCNTTYTTYAAYACNGGNYTNYTN AARGCNACNGAYYTNAAYGARGGNTGGGTNGTNGAYGARTTYAARCARACNGTNTGYATG CCNACNTAYYTNGTNTCNTGGGTNGTNGCNGAYTAYAARATHTCNGARGCNCAYGCNAAY AARGGNYTNYTNGTNMGNGCNYTNGCNCCNGARGAYAARATHAAYATGATGAARTTYGCN YTNGARAGYGGNGTNAARATHATHGARAARTAYACNACNTTYTTYGGNATHCCNTAYCCN ATGAGYAARYTNGAYYTNGTNTCNATHCCNGGNTAY---TCNGGNGAYGARGARAAYTGG GGNYTNGTNGCNTTYGCNGAYGAYGAYGCNYTNTAYGAYCCNGCNGARGGNAAYACNGAR CARAARYTNCARGTNGCNACNGTNGTNGCNCAYGARYTNGCNCAYCARTGGTTYGGNGAY YTNGTNACNATGMGNTGGTGGAAYGAYATHTGGYTNAAYGARGGNTTYGCNACNTAYATG ATGGCNTTYGGNGGNAGYYTNGTNYTNGAYCCNAGYTAYCARATHGCNGARTGGTTYATG AAYAAYTAYMGNGARCCNYTNAAYGTNGAYTGYYTNACNTCNTCNCAYGCNGTNCARTTY CCNGCNGAYAAYCCNAAYGGNATGGARAAYMGNGTNGGNAARATGGTNTAYCARAARGGN GCNTAYYTNATHCAYATGYTNCAYGGNACNATHGGNGARACNGCNTTYACNAARGGNYTN CARGAYTAYYTNGCNACNTAYCARTTYMGNAAYGCNGTNACNGARAAYYTNTGGGARTCN TTYGGNAARCAYYTNGARCCNGGNYTNTCNATGTCNGAYTTYATGAAYTCNTGGACNCAR AARGCNGGNTAYCCNGTNATHACNGTNACNMGNAAYAAYTCNGTNGTNAGYYTNGTNCAR GARMGNTTYYTNATHGCNAAR---------------------------GARGCNAGYAAY TTYACNTGGGTNGTNCCNTTYACNTAYAARYTNTCNTCNAAYGAYACNGTNGTNACN--- GTNTGGYTNAAYGAYGGNAAYGCNTCNGTNCARYTNCCNTCNGGNGAYATHTGGYTNAAR GGNAAYGTNGAYGCNGTNGGNTAYTTYMGNGTNAAYTAYGAYAAYGCNGGNTGGAARGTN YTNTCNGAYCARYTNAARAGYAAYCAYACNTCNTTYTCNYTNATGGGNMGNYTNAGYYTN GTNGAYGAYGCNTTYGARYTNGCNATGGCNGGNMGNYTNCAYTAYGAYGTNGTNTTYGAR YTNTGYAARTAYYTNGTNAAYGARACNGARTAYTTYGCNTGGAGYTCNGTNGTNGCNGAY ATHCARTAYATHYTNAAYMGNYTNAAYGGNGAYGCNACNYTNGAYAARTTYAAYTCNTAY TAYTCNMGNYTNGCNAARCCNYTNYTNGAYTCNGTNGGNTGGAAYAAYACNGGNCARTAY TAYGAYGAYYTNYTNAGYAARATHATHATHGGNYTNGGNGTNAARYTNAAYTAYGARCCN ATHGTNAAYAARGCNAARTCNTTYTTYGCNAARTGGAARAARGAYCARACNGTNTCNYTN AAYGAYYTNMGNCARACNATHYTNAAYACNGGNGTNAARTAYGGNAGYAARGARGAYTGG GAYTTYGTNTAYCARMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARAARACNGGNGGNAAR YTNGTNTAYGAYMGNGCNTAYYTNATGGARYTNMGNGARTGYGCNTCNTCNCARACNAAR CCNGAYGGNYTNCCNCAYYTNGARATHATHYTNGAYCARCCNGCNCCNTTYATGAGYMGN CCNTCN---GTNGGNCCNGCNGAYTTYACNCCNTCNTTYTTYCAYGCNAGYGGNGGNGGN CARMGNCAYGCNCCNCCNATHGGNAARAGYAGYAGYMGNGGNMGNCCNMGNCCNGGNGAY ATGCCNGGNACNCCNMGNATHATHAARAGYATHTCNATGTCNACNGAYGTNAAR---YTN CAYCARAGYGARAAYCCNTGGAAR------------AARAARGAYGAYAARAARGAYGAR GTNAARACNYTNGARGCNGARATHYTNTTYATHATGAAYMGNYTNACNCCNACNAAYTTY GARAARATGGCNGGNGARATGAARGCNYTNAAYGTNAARACNTAYGAYGAYYTNAARCAR ATGGTNAAYATHTTYTTYGAYAARGTNACNYTNGARACNAARTTYGTNGARGCNTAYGCN YTNYTNAGYAARGTNATGTCNGGNYTNMGNGTNACNCCNCCNACNGAYGGNACNGTNAAR GAYAGYATGGCNACNTTYMGNGTNGTNATGYTNACNAARTGYCARCAYGARTTYGARGCN GAYAARTCNGTNGTNTTYGARGCNCCNGARGARAARAARAARAARYTNCARGCNGARAAY CCNGARATHACNCCNGARMGNGAYGCNATGATHGARAARACNYTNTAYCAYATGAARYTN MGNMGNATGAARTTYTAYGGNAAYATHMGNTTYATHGGNGARYTNTTYAARYTNGGNATG YTNACNGARAAYATHATGCAYGAYTGYATHTTYMGNYTNYTNAARGCNMGNGAYGAYGAY TCNYTNGTNTCNYTNTGYAAYYTNYTNACNACNGTNGGNMGNAAYYTNGAYACNGAYAAR GCNMGNCCNMGNATGGAYCARTAYTTYTCNCARATGGGNAARATHGCNGAYGARMGNAAR TCNMGNATHAARTTYACNYTNMGNGAYGTNATHGAYYTNMGNCAYAAYCAYTGGGTNCCN MGNAARGARTCNGCNGGNCCNAARAARATHGAYGARGTNCAYAARGAYTAYGCNCAYGAR CARGCNMGNAAYCARTTYYTNGCNTCNCARCCNCCNCCNCCNMGNAAYGAYAAYGTNCAR GCNGGNAGYMGNAARGGNAGYMGNCARMGNCARGAYGARAAYMGNATGAGYGARGAYGGN TGGAAYACNGTNAGYTCN---AAYAARATGMGNATGATHGAYGCNAAYAARATGAARATH TCNAAR---AGYGTNGTNGAYGAYAAYATHCARYTNGGNCCNGGNGGNGGNGCNCAYMGN ---CCNATGTGGAGYMGNGGNAGYCAYGGNGGNGCNCAR------CCNCARGAYGAYMGN CCNACNYTNGCNCCNAAYMGNTTYTCNGCNYTNACNAAYGAYGAYGGNMGNAARTCNTTY CCNMGNTCNCCNTCNMGNGGNGARGGNGGNGCNGGNMGNGGNYTNMGNCARGGNCARACN GCNGGNCAYGGNMGNGGNAARYTNATGACNMGNTCNAGYCARGARGGNGAYMGNMGNGAY GCNATHGCNAAYACNMGNTCNTTYATGGGNGGNMGNTCNCARAAYTCNAGYMGNGAYAAY AGYTGGAAYMGNGAYGAYMGNMGNCARTTYATGGGNCCNMGNGGNTCNTAYGARMGNGAY AAYCCNATGACNMGNAGYGAYAGYGCNGTNAAR---------GARTTYAARGCNCCNGCN CCNCCN------GCNGTNAARCARATHAGYGAYTCNGAYYTNGARAARAARGCNAARAAY ATHYTNGAYGARTAYYTNAAYATHAARGAYYTNGARGARGCNMGNYTNTGYGTNAARGAR YTNAARGGNCARGAYCAYYTNCAYYTNTTYGTNACNTCNTGYATHAAYAGYGTNYTNGAR TCNAARAGYGARGCNMGNCARAAYACNGGNAAYYTNTTYCAYGARYTNGTNAGYAGYAAY ATGYTNACNTCNAGYATGTAYATHAARGGNYTNAAYGARGTNYTNCARTAYGCNAGYGAY ATGGTNGTNGAYATHCCNACNYTNTGGACNTGYYTNGCNCARGTNATHAGYCCNYTNYTN GTNGGNGGNACNYTNACNTGGCCNATGYTNAARGARGCNATGAGYCCNCAYYTNGAYAAY MGNGAYGGNGCNAARYTNATGGCNTGYGTNYTNTCNCARTGYGTNGARAARCARGGNGAR AAYGAYGTNTCNCARAARTGGCARAGYAGYGGNYTNAGYTGGTCNATGTAYYTNAAYGGN GAYGARGTNGARTCNTTYGTNAARGAYAARAAYYTNGGNTTY---------ACNYTNGGN GAYGCNTCNGGNTCNGCNAAYCCNYTNCCN------------------------------ GARYTNGAYGAYATGATHMGNAGYMGNGCNCCNACNAAYTCNATHYTNTCNTAYATHGAR AARTCNACNACNAAYAAR---TCNGAYGCNAGYTTYATHMGNGCNYTNACNACNTCNATH GTNTCNTCNTCNATGACNGAR------------AARMGNTTYAGYGARGARGTNTTYYTN AGYCAYAARGARATHYTNAARMGNTAYATH---GGNAGYGAYYTNGGNYTNCARYTNCAR GCNYTNTAYGCNYTNCARACNYTNATGGCNAARYTNGARCAYCCNTCNGGNGTNYTNTCN AARGTNTTYGARYTNGTNTAYGAYGARAAYATHGTNGARGARGAYGTNTTYTAYAARTGG GARAARTGYACNGAYCCNCARGARCARGARGCNAARGGNACNTGYGTNATGCARACNMGN CARTTYTTYGTNTGGYTNMGNGARAAYGARGARCCNGARGCNGARTCN------------ ------------------------------------------------------------ ------------------------------CCNCARGARTCNAAYGAYGAYTGGATGGAY GARYTNAAYAAYYTNGGNGAYCCNYTNGGNGAYGAYAGYATGGARGCNTTYGTNAAYYTN GAYCARTTYYTNAAYGGNAAYTCNTTYTTYGAYGAR------GARGGNAAYYTNACN--- YTNAAYACNACNGCNGARGTNACNCCNATHATHGAYTTYGGNCARCAYTCNGGNGAYGCN ATHYTNAAYCARGAYTTYYTNYTNCCNCCNGARGARCARGTNGTNATHCARCAYCCNCAR AARACNTGYMGNAARMGNCCNGCNCCNTCN---------GCNATHAARACNAGYYTNTAY GARATHCCNGCNACN---------------ACNTAYACNACNACNGTN------GARCAR GTNYTNTCNGAYACNGARYTNGAYCAYGAYTAYAGYTCNAARMGNCARMGNATGTCNACN CCNTCNGARATH---------------TAYAARCCNTCNACNAGYGGNACNGTNACNAAY AARAARTCNTCNMGNCCNTCNAGYYTNCCNCARACNGTNYTNACNCCNTCNGAYGAYTAY GARGAYGGNGTNTTYYTNGAYAAYAGYATGGAYAARCARACNGTNMGNMGNATHAARAAY AAYTAYGCNTCNAARMGNTCNMGNGARCARMGNAARCARAARYTNAGYGAYATGGAYATH GARGCNGARGAYYTNGARGTNMGNAAYCARGARYTNMGNGARAARATHGTNCARYTNGAR AARATGGCNAARGARATGAARACNGCNYTNGTNGCNAARATGACNGGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GGNGCNGARGTNTCNGCNGGNAARAGY GARYTNTCNTCNTCNTCNGCNCCNCCNTCNCAYCCNGCNTCNGAYCCNCCNCCNGAYGGN GARGGN---GGNGCNACNGCNAGYGGNGCNAGYGCNTAYAAYAARGAYATHGTNCCNGAY ATHAAYAARAAYAAYMGNYTNAARGAYACNTCNGGNGTNACNAGYAGYTCNCARTCNTTY GTNTTYGGNAGYAAYYTNTCNCARMGNGTNACNGGNTTYGCNTCN---TCNCCNGCNGAR AAYGARGCNGCNCCNTCNTCNGGNTTYGTNTTYGGNCARTCNYTNGCNTCNMGNGCNATH GTNGARACNAAYGGNTCNGCNCARCAYAARGAY---GARGARAGYGAYTCNGAYTCNGGN AAYAARYTNAAYCARACNYTNGARGARTCNGCNAARGARTAYCARGCNAARCAYGAYAAY AARACNGARYTNAARGTNGTNGARACNATHACNGGNGARGARGARGARTCNAAYGTNYTN CARGTNAAYGCNAARYTNTTYTTYTTYGARACNAGYAAYGAYACNTGGATHGARMGNGGN MGNGGNACNATHMGNYTNAAYGAYATGTCNGCNAARGAYAAYACNAAYTTYCARTCNMGN YTNGTNATGMGNACNCAYGGNAGYYTNMGNYTNGTNYTNAAYACNAARATHTGGCCNGGN ATGTCNYTNGARMGNGCNTCNCCNAARTCNATHMGNATHACNGCNATGGAYACNGAYGAR ACNATHMGNATHTTYYTNATHACNACNAAYGTNAARGAYTCNGARAAYYTNYTNMGNGCN ATHGAYTGGMGNATHCARCARYTNAARATHCARGARGARCCNTCNMGNCARTCNTCNGAR GCNMGNACNGGNGAYAARMGNAARGCNGAYGAYTCNGAYTTYGARCAYCCNCAYAARAGY AARAARGTNAAYAGYTCNCCNGAYCARAGYATHTCNATHAGYAARAARGARGARTCNGAY AGYAGYGTNCARGAYCCNGARACNGARGCNTCNTGYGARAGYCAYTCNTCNTCNYTNACN ATHAARTCNGARTCNGAYTTYCARTGYATHCAYTGYGGNTGYGARGTNGARAARYTNTAY CAYGAYTAYAARGCNGGNACNATHAARYTNATGAAYTGYAARYTNTGYGGNAAYGTNGTN GAYAARTAYGTNGARTAYGAYTCNAGYATHATHYTNYTNGAYGTNYTNYTNYTNCAYAAR CCNGCNTAYGCNCAYYTNYTNATHAAYGTNAAYGTNAARTCNTAYTGGMGNGCNGCNGTN YTNYTNTGGGTNATHCARGCNTTYGTNAARYTNATHCARCARMGNTCNGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHACNYTNAARGARGGNMGNGAYYTNGTNGTNMGNGAYAGY TGYGGNACNAGYGAYCCNTAYGTNAARTTYAARTAYGGNGGNAARATGGTNCAYAARAGY MGNACNATHYTNAARAAYYTNAAYCCNMGNTGGGAYGARCARTTYACNATHCCNGTNGAY GAYATHGAYAARCCNYTNGGNGTNAARGTNTAYGAYTAYGAYMGNGCNTGGAAYGAYGAY CCNATGGGNACNGCNGARGTNGAYYTNTCNACNYTNGAYGARAAYAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARGGNTAYAARYTNCARGTNGARAAYGTNCAYCAYCCNATG AARACNYTNACNGARGTNATGGARTTYTTYGTNGTNACNTCNGGNCCNCARTCNACNAAR CCNATGACNTGYAAYAGYYTNCARGARYTNGGNATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGCNTCNTCN AAYYTNTCNMGNACNYTNGCNAARTCNYTNAARGGNMGNACNTTYGCNGCNGCNGCNGCN GCNCARGCNGARAARGTNAAYGCNGCNAAY------------TGYTCNATHAARACNYTN GAYAAYGGNYTNCAYGTNGGNGTNATHAAYTCNAAYTCNCCNATHGCNMGNGTNGCNGTN GTNGCNCARGCNGGNTCNMGNTTYGARAAYGGNGAYGAYYTNGGNATHTCNCAYTTYYTN MGNATGTCNAAYAARYTNMGNACNATGACNCAYTCNAGYATHGGNMGNACNMGNACNATH CARCARYTNGGNGCNGAYYTNACNATHATGGGNACNMGNGARTAYATHTAYTTYAARAGY GCNGTNACNMGNAAYTGYYTNAARGAYGTNGTNACNGTNYTNMGNGAYGTNACNACNTAY CARGCNTAYYTNCCNTGGGARGTNGCNGAYATHCARAARGAYCARAAYGGNATGGCNYTN GAYYTNGCNGTNYTNGAYACNMGNCCNGAYATHGGNGCNYTNGARYTNYTNCAYTCNGCN GCNTTYMGNAAYACNYTNGGNAAYTCNYTNTAYGCNCCNGARCAYATGATHGGNAARTAY GARCCNAARCARYTNATHCARCAYGTNMGNAARYTNTTYGGNAAYGGNMGNATHGCNYTN GTNGGNATHGGNGTNGAYCARGCNGARYTNGARGARYTNGCNTCNACNTTYGAYCCNYTN AARCCNTCNGGNGTNACNACNGARAARGCNACNTAYTAYGGNGGNGGNGARYTNMGNCAY AAYGTNGGNGGNGGNYTNGCNCAYGTNGCNGTNGGNTTYCARGGNCCN---------AGY AARGAYYTNYTNGCNGTNGARGTNYTNMGNCARATHYTNGGNTCNGGNCCNCAYATHAAR TAYAGYAGYGGNACNTCNGCNGCNYTNYTNGCNAARGCNGCNGCNGGNGCNACNGAYGCN CCNTTYCAYGTNTCNGCNYTNAAYGCNACNTAYTCNGAYAAYGGNYTNTTYGGNTTYACN GCNGTNGCNCAYGCNTCNCARATHGAYAARGTNGTNCARGCNGCNGCNAAYCARYTNAAR GAY---YTNGCNACNAAYGTNTCNGAYAARGAYATHGCNMGNGGNAARAAYCARYTNAAR GCNGARATHTGYATGCAYTTYGARAAYCCNGAYGTNYTNYTNAAYTGGYTNGGNGARCAR GTNTTYCAYGGNAAYGAYGTNGTNACNCCNGARGAYATHTAYAARATGGTNGAYGGNATH AAYGCNTCNGAYGTNAARAAYGCNGCNGGNACNGCNYTNAARTCNAGYCCNTGYATGGCN GCNGTNGGNAAYACNACNAAYGTNCCNTAYYTNGAYAARYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNYTNTTYAARAAYYTNCAYTAYTTYYTNTGYGGN TTYGTNAGYYTNTGYTGYYTNACNGGNTTYGGNAAYTTYGTNGTNTTYATHYTNCCNTCN AGYTAYAAYACNGTNTCNTCNMGNGGNTCNGTNGTNGCNAGYTTYYTNTGGAAYGGNGGN YTNATHYTNYTNTTYATHGGNCARCAYTCNTTYATGGCNACNCCNTGGTTYAARMGNCAR YTNCARTCNTGGYTNGGNATHTCNGTNTCNGARMGNYTNGTNTAYYTNTTYGGNACNAAY YTNTGYYTNYTNYTNATGATHGTNTGYTGGCAYMGNATHCCNGAYGTNTAYYTNTGGGAY ATHGAYATHGARAAYCARTGGYTNYTNTCNACNTTYTTYYTNYTNYTNCAYATHGCNAGY TGGATHGTNATGGGNYTNGARYTNYTNYTNATGGAYATHGGNCARTTYYTNGGNATHACN CARGTNTAYAAYTAYCAYAAYAAYCARCCNCCNCCN---YTNACNAAYAARAARMGNMGN NNNMGNGARYTNTTYTCNMGNATGMGNCAYCCNGGNCCNATHYTNYTNTCNGTNYTNYTN TGGYTNCARCCNGCNATGACNYTNGAYMGNGTNYTNYTNGCNTCNGTNTTYACNGCNTAY YTNGTNYTNTGYAARGAYTTYGARCAYCARCAYTGYAARTGGGCNAARAARTAYTAYAGY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGGAARACN AARGARGTNGCNGARTGGTCNGAYGCNGTNGGNYTNGGNGARCAYACNTCNYTNTTYYTN GGNAAYAARATHGAYGGNATHCAYYTNYTNACNACNGAYGGNYTNCAYYTNCARMGNYTN MGNGTNAAYACNGCNCARGARGCNGTNMGNATHGARAAYCARATHMGNGARYTNAAYTAY GCNAARMGNCARTGYGTNGGNAAYATHGARACNYTNCCNTAYATGTAYTAYAARGCNYTN AAYYTNGGNCAYCAYCCNCCNCCNMGNTAYTAYGGNGARYTNYTNCAYTAYAGYGCNAGY TTYTTYCCNGGNTTYMGNACNGCNCARGAYTAYATHGCNGTNGGNAARGTNAAYCARTGG TAYGAYTTYTGGAARATGGCNYTNACNCAYAARTGYTGYGTNTTYATHMGNATGTGYGTN AGYACNMGN---AARMGNGARAARGAYGAYTAYGGNCCNACNGARGTNAAYGCNGTNCAR ACNTTYAGYGAYATGAAYGTNCARYTNACNAAYCARACNTTYGGNAAYAARTTYACNGTN MGNGARATGAARGTNTCNAARGGNAARGTNACNMGNAARGTNGTNTGYTTYGAYYTNAAY ---------------YTNCAYGGNYTNATHGTNGAYGAYATGYTNACNTTYGGNMGNCAR GTNMGNAARCARCARCCNGCNAAYGCNACNCARCCNATHGTNATHCARTCNAGYGARGGN GTNACNAARACNTCNMGNATHATHGCNYTNGAYTAYTTYATGCARTTYGTNGAYTCNTCN GGNMGNGAYAAYGTNATHGAYGTNTTYGAYTAYGTNTCNATGYTNMGNAARCARMGNCCN GGNATGGTNGAYACNGTNGARGARTAYGTNACNATHAAYGCNGAYGTNGCNGARYTNATH MGNAARATGGARAGYGAYYTNGARYTNATHCAYYTNTAYCARCCNCCNTCNGAYTGYGAY GGNGTNMGNTGYAAYGAYTGGYTNCCNACNTTYYTNTAYTGYATHGTNGTNCCNGTNGCN GTN---GTNTTYATHYTNATHYTNATHGTNGTNATHTGYAGYTGYMGN---AARTCNTGY AARTGYAARAARTAYTCNTCNYTNATHGGNGARAAYAAYAAYATHCARYTNGARGAYTAY AAYACNATHMGNMGNGCNTCNYTNAGYYTNMGNCARATGTCNCAYAAYMGNGARACNCCN ATHATGGGNAGYMGNTCNGGNTCNTCNGCNACNYTNGAYMGNTCNTGYMGNMGNAAYMGN MGNGGNMGNGARTCNTGYAAYTCNGCNCCNGGNACNYTNCARMGNCARAAYMGNMGNCAR TCNACNACNGAYGAYGARMGNCCNYTNCCNCCNTGYCARTCNGAYYTNGGNGTNTCNAGY GAYGGNCARMGNCCNTCNCCNCCNCCNTAYTCNATGCARTCNAAYAGYGGNYTNTTYGGN TCNGGNACNGTNCCNTCNGGNGAYGTNCARACNAGYTTYATHTCNGAYAAYTCN---GAR MGNAAYGGNCAYGGNTCNCARGCNYTNYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ACNAAYGARGAYGGNCCNTCNTTYTCNTTYAAYTTYYTNATH GCNYTNGCNGCNAAYMGNMGNYTNTTYYTNAARTCNGAYATHMGNAARACNAAYAARAAY GGNGTNMGNGGNAAYYTNTGGYTNATHAAYCCNGAYAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TGGAARGCNAARTGYATHAARYTNGARAARGTNATHAARACN YTNTCNAAYCAYTGYGTNMGNGTNATHGAYCARCAYGARGAYYTNYTNATGAARTTYMGN AARAAYCARGAYCARTTYAAYCARATGAARACNAARTAYCAYGARMGNGGNGARCARATH AARAARGCNMGNGARGTNYTNGTNCCNATHTCNAAYGARYTNAARATGYTNMGNGARAAR TAYGARATHGCNGTNGCNTGYCARGTNCARGCNGARACNTTYGCNATHGARACNACNAAR ACNAAYAARAARYTNCAYMGNCARAGYCARATGYTNCARGCNAAYATGAARGCNAAYCAR YTNGTNGARATHAAYATHGAYGAYGARGARCARGGNGAYGARGARGARAARAARTAYATH GARAARYTNGGNCARCARATHGAYGARYTNGARGARGARAARACNGCNYTNAGYYTNCAR ATHAARACNATGAGYAAYAGYYTNCAYGARGARCARGARACNAAYGARCAYYTNAARGAR AARGTNGCNATGATGAARGAYGARYTNCAYCARTAYAARCARACNGTNAARCARCARGAR GAYYTNYTNCARCARGTNGCNACNTCNTCNGARAARGCNTTYYTNGARTAYCARGAYATG GARCARACNTAYAARCARGARATHATGGTNMGNAGYCARGCNGARMGNGTNGCNAAYMGN YTNCAYACNGARMGNGAYCARGCNMGNMGNGARAGYGCNATGGCNYTNAGYAARGTNGCN GAYAAYAARAARYTNATGGAYGCNATGYTNGARATHCARGAYYTNAAYAGYAARTCNGTN CARATGAARGARGARTTYGARAARCARATHYTNGARYTNAARGARCARGTNAARGCNGCN AARGARGTNTAYGAYGCNGARGCNGTNGAYGCNGARAAYGARGARYTNATHGARGARAAR AAYGAYYTNCARGARAARYTNGARAARAGYGARGARGGNATGAARCARYTNAAYACNAAR TAYAAYGAYYTNYTNGARACNTAYAARACNYTNGARAGYAARTAYAARGARGCNACNACN GTNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNGCNCCNACNAARAARTCNGARGGN TTYYTNTCNMGNATHTAYGGNMGNAARGCNCARMGNGARAARGCNAARGARAARYTNAAR AARGGNGGNGTNACNATGAAYGARGGNCAYACNAARGCNATHGARGARATGATGAARMGN ATHCARGGNGGNAAYATHGGNYTNAARCCNGTNYTNCARMGNMGNACNCAY--------- ------CCNGARAARGARGARACNAGYGCNATHTCNGARYTNCARGGNYTNYTNAGYAAR ATGMGNAARTCNMGNAGYGARGAYGAYYTNTCNGTNTTY---GAYGAYTCNGGNGTNGAY GARAAYTCNGARYTNGGNAARATHTTYAARAARMGNATHCAR------------------ ---------GGNGTNCCNGARTCN------------------AAYCCNAAYCCNGARCCN GARACNMGNCCNAARCCNYTNCCNMGNAARYTNTCNACNATHCCNGAYGTNCCNGARGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CAYCCNTAYTCN ACNGGNAGYATHCCNAAYTCNGCNGGNGAYAAYAAYGCNTCNYTNCCNGCNTCNGTNACN GCNYTNTTYAAYMGNGCNGGNCCNGCNGGNTCNTCNNNNNNNNNNATHTCNAGYAAYAGY AGYTAYAGYGCNCARGAYGCNGARGCNCARYTNAARGCNATGYTNTTYGGNGGNACNMGN GAYTCNGCNTCNTCNAGYGGNACNGCNTCNCCNGCNGGNCCNCAYCCNAAYTTYCARMGN MGNATHAARACNGTNGCNGARYTNGARGCNGAYATGCAYCARAGYTCNCCNCARAARMGN GARCARCCNCARCCNMGNCCNACNGARGGNAAYAAR------GAYATGACNGCNTTYAAY AARTTYYTNATHATGATHAAYGCNGCNGCNGARGCNAAYCARAAYGCNTCNCAYAARGAR GTNCCNCARACNTCNGCNGCNGGNTAYGGNATGGTNCCNAGYCAYAGYGARTTYTCNCAR GCNATGYTNMGNAAYAARGARCAYCARYTNCARYTNCARCARCARTCNGTNAAYYTNCCN CCNCARGCNATGTCNACNCCNCAYGCNACNGGNAAYTCNTCNGAYCCNATHYTNAAYYTN ATHCARCARAAYCCNTCNATHYTNATGAARCCNGTNACNTCNTCNCCNAAYAAYCCNACN ATGTTYGCNGCNCARCCNTCNGGNATGCCNTCNAAYGCNMGNGTNGTNTCNCCNYTNYTN TTYAGYCARCARCCNCCNYTNCAYYTNAAYGCNCCNTCNCCNATHCAYCCNTCNCARYTN TCNCCNTCNTCNYTNACNCARTCNCCNGTNYTNCARMGNGGNATGAGYCCNCARGARYTN GCNGCNCAYGCNCARGCNGTNATGCARAGYCARYTNYTNAARMGNCARCAYCARAAYCAR AGYGARMGNTTYAAYMGNAARCARGARAGYMGNTCNAARTCNCCNCCNGGNCARATHAAR GTNGTNAARCCNCARCCNGCNGCNCARCCNGTNYTNCCNCCNACNCCNCARCCNAARGGN TCNACNGTNAAYACNTTYACNCCNACNTCNGTNYTNGTNAARATGCAYTCNGAYAARGCN CARGARAARGARAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNTTYTCNYTNYTNTTYYTNTGYCCNYTNCCNGAYAAYCCNTCNYTNTAYCARACNATH TCNCARYTNMGNGTNGCNATHAAYGTNGARYTNYTNGAYTAYMGNGARTAYYTNAAYGTN AARTCNCARMGNAAYATHACNATGACNAGYTAYTTYGARAARTAYCCNGGNYTNATHCAY TTYATHTTYGTNGAYMGNMGNATGCAYCARATGACNGTNCCNGCNYTNAAYATHTCNYTN AARGARGGNGARACNGCNAAYACNAGYTCNTAYYTNAARCARAAYATHTGGMGNATGTAY CARCAYATGATGGARAARYTNTCNGARGGNTAYACNACNATHATGYTNCARGARGGNGAY TTYCAYTAYTCNTAYTTYYTNTGGTTYGARGAYAGYGCNGGNAAYCCNYTNGCNGTNCAR GAYAGYTTYAARCCNACNAGYAARTGGTCNTAYCCNGGNATHYTNTGYGGNTCNTTYTAY MGNGAYATHATHCARCARTGYTTYCCNCARACNYTNAARAAYTCNGTNTTYTGYTTYGAR ATGTTYATGATGCAYGTNGGNAGYGTNCAYCCNCARTAYATHGCNATGCAYTCNAARAAR YTNGCNGCNGARYTNTGGGARATGTCNGGNGAYGCNTAYACNACNYTNAGYYTNTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TCNCARMGNCARTCNGCNACNAGYAGYGCNAGYGGNAARATGAARMGN TCNGARMGNCAYATGATGMGNYTNAARAGYATHATHACNAARGCNYTNTCNGARAARGGN GTNAARGARAAYAAYGCNATHCAYCARGCNTGYGCNAARAAYYTNYTNAAYGTNAGYATH GTNYTNYTNAARACNYTNCCNAAYTCNCARAAYYTNACNGCNGARATGAARTCNGTNGTN TAYGGNCARGTNCARCARATHATHAAYYTNGARAARMGNMGNTCNGGNATHTCNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARTCNAGYTCNAGYTCNMGNAARAARNNNNNNMGNAGY MGNAGYAARAGYMGNGAYMGNAARMGNTCNMGNAGYMGNGARMGNAAR------------ ---------------------------------------MGNGAYGGNMGNMGNMGNAGY MGNAGYMGNGAYMGNAGYMGN---GARMGN------------MGNMGNMGNAGYMGNAGY AARAGYMGNGAYMGNMGNMGNMGNAGYMGNAGYMGNGARMGNAARMGNGGNTCNAGYMGN AGY---------MGNGARMGNYTNCCNGARYTNACNGTNGARGARMGNGAYGTNMGNACN ATHTTYTGYATGCARYTNTCNGCNMGNATHMGNCCNMGNGAYYTNGARGARTTYTTYTCN TCNGTNGGNAARGTNMGNGAYGTNMGNYTNATHACNGAYAAYAARACNMGNMGNTCNAAR GGNATHTCNTAYGTNGARTTYGCNGAYCCNGARTCNGTNACNYTNGCNATGGGNYTNACN GGNCARAARYTNYTNGGNGTNCCNATHYTNGTNCARCCNTCNCARGCNGARAARAAYMGN GCNCARCCNGCNACN---GCNACNCCNACNCARAARYTNGCNCCNGARGGNCCNYTNMGN YTNTAYGTNGGNTCNYTNCAYTTYAAYATHAGYGARGAYATGYTNMGNGGNATHTTYGAR CCNTTYGGNAARATHGTNGAYATHAARATHATGAARGAYCAYGARACNCARMGNTCNYTN GGNTTYGGNTTYATHAGYTTYGCNAAYGCNGAYGAYGCNAARAARGCNYTNGAYCARYTN AAYGGNTTYGARYTNGCNGGNMGNCCNATGAARGTNGGNCAYGTNACNGARMGNGGNGGN GARGGNCCNCCNCAR------AAY------GGNGTNGGNGGNCAYYTNGAYACNGAYGAR ATGGAYMGNGCNGGNATHGAYYTNGGNGCNACNGGNMGNYTNCARYTNATGGCNAARYTN GCNGARGGNACNGGNTTYCARATHCCNCARTAYGCNGCNAAYGCNYTNAAY------ATG AAYAAYCCNCCNCCNGCNGGNGTNCCNCCNGTNGTNCCNGGNTCN--------------- ACNGGNGTNCCNATHAAYATHGCNACNATHCCNACNCCNGCNCCNCCNCCNCCNCARCCN CCNGCNGTNACNCCNGCNCCNCCNATHGCNACNCARTGYTTYATGYTNTCNAAYATGTTY GAYCCNATHACNGARAGYMGNYTNACNTGGGAYCARGARGTNMGNGAYGAYGTNATHGAY GARTGYAAYAARCAYGGNGGNGTNYTNCAYATHTAYGTNGAYAARAAYTCNCCNCARGGN AAYGTNTAYGTNAARTGYCCNACNATHTCNGCNGCNGTNGCNTCNGTNAAYTCNYTNCAY GGNMGNTAYTTYGCNGGNMGNGTNATH------------------------------TTY ATGGGNCARAARCCNGAYATGGCNCCNTCNAARGCNCAYTTYACNATGAGYGARGARYTN MGNTCNTCNACNATGTCNYTNAGYAARMGNAAYATGGTNATGGAYGARGAYMGNTTYGAR GAYCARTTYYTNMGNTGYGGNATHTGYAARAGYMGNTTYGCNAARGGNTGYYTNCCNMGN YTNYTNCCNTGYCAYCAYTCNTTYTGYCARCCNTGYATHGTNCARYTNTAYCARACNGCN AARGARCAYMGNYTNAAYYTNCARTCNACNYTNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYATGTTYTGGTAYYTNTTYYTNGAYAARTTYCARAARTCN CARAAYTAYCARTCNAARYTNTTYAAYMGNATHTCNCAYAAYTAYGTNAARYTNATGATG GCNMGNGTNGAYCCNATHGCNAARGAYACNTTYTTYAARGAYTAYCCNAARYTNATGTCN CARGCNATHTAYGCNTCNTTYTGYTTYTGYTTYCCNGAYTCNTAYMGNCARTTYGGNGAR ACNTTYAARGAYGARYTNACNTAYYTNGTNTAYGGNTGGATGGCNGGNATHMGNCCNGCN CCNMGNAAYTGGYTNTCNTGGGAYATGGCNCAYYTNGARCCNCCNAAYYTNAARATGMGN GARGAYYTNATGCARAARAARAAYAGYAARAARATGACNTCNTTYATHGAYTTYGAYTAY YTNGAYTCNYTNATHTCNACNAAYGCNAGYCARTAYGCNTCNACNATGTCNYTNGCNCAR TCNACNTCNAARGGNTCNACNAGYTCNAAYATHACN---TCN---MGNAARCCNMGNATG CAYGCNMGNATHAGYAAR---ACNCAYAARCCNTTYYTNMGNACNTCNTCNCCNAAYAAR GCNCAYTCNCCNTCN---TCNCARGAYATHAAYYTNATHGAYGCNGTNGCNGAYGCNCAR AAYAGYCCNGGNAAYMGNGCNAARGARAARMGN--------------------------- GGNAARGAYGGNAARMGNCARAGYGARGCNYTNACNCCNATHMGNGARATGGCNAGYGAR GAYGARGGNGARGAYTTYGARAARAARATHTCNCARATHTCNATGAGYCARATHMGNGAR ---AARGCNAARAARGARAAYGTNATHGARTCNCAYCCNYTNGGNAARGGNTGYCARTTY ATHMGNACNGCNTTYAAYGTNGARGGNMGNAGYCCNYTNGTNGCNCAYTTYYTNCAYATG AARGGNYTNGCNCARGAYGTNGGNCARAAYATHTGGATHCARMGNGTNGARGTNGAYAGY YTNCCNGCNYTNGAYGCNACNACNTAYAGYGAYYTNATHGGNAAYTCNTCNAARACNATH AARAARYTNGARTCNGGNTTYCARGAYATGTAYCAYAARAAYACNAARGAYAGYCARMGN TTYATGMGNGAYCARCARAARATGYTNMGNGARCAYATGMGNAARCARTCNGCNYTNYTN GCNAAYAARGARGARGTNAARGTNYTNTGYGAYYTNATHATHYTNGAYCARMGNAARAGY CARGAYTCNGTNTCNGCNGGNGCNAAYGCNGCNATHGARGCNGCNYTNATGGCNCARGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNGCNATHAAYTTYGGNTGYGARCARGCNTCNTAYAAYAAYCCNCARMGN AAYGCNTTYGTNGGNTAYAAYMGNTCNAARGTN---YTNAGYAARGARYTNATGTCNTCN GTNGCNGTNTCNAARTCNGAYTTYGGNMGNCCNMGNAARMGNMGNATHMGNGAYGARAGY GGNATHTGGGTNGAYGARAARGARYTNGARGGNAARACNATHGARCAYGGNGTNGTNGAY AARAAYAARAGYGCNACNAARAARGGNAARGCNGTNAARCAYGTNTAYAAYCCNTTYAAR YTNGTNCCNTGYYTNCCNTTYACNACNGARAAYCARGARCCNTAYAARATHGARGTNTTY AAYACNGCNYTNTCNATHATGGAYATHCAYTCNCAYATHTCNAARACNGARGTNATHGGN ATGYTNGGNGGNMGNTTYGAYGARGAYMGNMGNTGYYTNACNGTNACNATGGCNATHCCN TGYAARAGYATGAGYACNGGNATGCARTGYGARATG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN ACNGARYTNTGGGCNAARCCNATHAAYCAYYTNTGGCARTTYTCNAAYAARGAYAARAAY GCNGTNMGNMGNTTYAAYTAYATGATGTCNTTYMGNAGYCCNCAYTGYTGYATHTGYTCN YTNTTYMGNAARTTYGARCCNGARAARGARTGGCCNAAYYTNYTNAGYGGNAARYTN--- ---GARTCNGTNGTNATHCCNTCNMGNTCNYTNCCNATGATHCCNGARTCNTCNTTYGCN ATHAGYGTNTCNAAYMGNACNCCNTTYTGYGAYTAYTCNCCNYTNGAYGARGAYGGNYTN AGYACNYTNYTNATHTGYGCNAGYTGYAAYATGTGYGTNCAYGCNAGYTGYTAYGGNGAR TTYMGNAARCCNAAYCAYGARGAYTGGCARTGYGAYGCNTGYGTNTCNATGGARTTYAAY GARGAYATHGAYTGYGTNYTNTGYTAYATGMGNGGNGGNGCNYTNAARCARACNTCNGAR GGNCARTGGGCNCAYGTNGCNTGYGCNYTNGCNATHAGYGAYGTNTCNTTYAARAAYATH MGNTAYMGNGCNCCNGTNGTNGCNACNAARATHGAYCCNGARMGNTTYCAYYTNAARTGY ACNYTNTGYGGNCCNGTNTCNCARCAYGTNGAYTAYCCNMGNCCNTGYATHCARTGYTCN CAYGGNMGNTGYACNGTNGCNTTYCAYGTNTCNTGYGCNTTYATGGCNGGNATHAARTTY GARATGAGYGAYTGGCCNGTNCCNACNTAYATHTCNTGYMGNAARCAYYTNCAYTTYMGN CARAARAAYGAYGCNMGNMGNGAYATGCCNGAYYTNGGNYTNTGYAGYYTNGCNYTNGCN AARCAYAARAAYAARMGNTAYTAYTGGGCNAARGTNYTNMGNGTNGAYMGNAARAARYTN TAYGARGTNGAYTTYGAYGAYGGNTCNTAYAGYGARGAYYTNYTNCCNGARGAYATHCAR AGYCAYAAYTGYYTNMGNGAYGGNCCNCCNATGCARGGNCARCAYGTNYTNATHAARTGG GARGAYGAYAGYYTNTAYGGNGCNACNTTYMGNAARGTNAAYAAYAARGAYATHTAYACN GTNGARTTYGARGAYGGNTCNYTNYTNCARGCNAARMGNAAYGARYTNTGGGGNGARACN GARGARATHCCNAARCAYATHCARAGYMGNATGTCNAARGCNACNGARCARMGNYTNTTY GARGARGARTCNCARGAYGGNTCNMGNAAYMGNMGNAARAARAARGTNGAYTAYYTN--- AARATGYTNGGNATHATHAARTGGATHCCNCARTAYMGNGGNGAYACNTTYGTNGCNGAY YTNGTNGCNGGNYTNACNGTNGGNYTNACNGTNATHCCNCARGGNYTNGCNTAYGCNTCN ATHGCNAAYYTNCCNCCNCARTAYGGNYTNTAYTCNGCNTTYATGGGNTGYTTYGTNTAY TGYYTNATGGGNACNTCNAARGAYATHACNYTNGGNCCNACNGCNATHATGTCNYTNATG ACNGCNACNTTYGGNTCNCCNGTNGCN------GGNGAYGTNACNYTNGCNGTNYTNYTN ACNYTNATHTCNGGNGTNGTNCARYTNYTNATGGGNGTNYTNAARYTNGGNATHYTNGTN AGYTAYATHTCNTAYCCNGTNATHAAYGCNTTYACNTCNGCNGCNGCNATHACNATHGCN TTYGGNCARGTNAARAAYATHYTNGGNYTNAARGAYATHGAYMGNGARTTYYTNCAYATG GTNTAYGARACNTTYGARAARATHCCNGARACN------------GARYTNCARYTNYTN YTNAGYYTNCAYAARTCNYTNGTNYTNGAYGARCARACNCARAARATHAARTGYAGYYTN ACNAAYCAYGARATGCCNGCNAARGTNTCNGCNATHGARAGYTAYGTNAARGGNAARAAR TAYAARMGNYTNGCNGAYYTNGAYTCNYTNTCNTAYGARGARCAYAARCARCAYATHCAR CCN------AAYAARAARMGNGARAAYGARATGTTYTGYMGNYTNACNYTNMGNCAYYTN GARAARACNGCNTCNGCNATHCARMGNCAYYTNAARGGNAARAARTAYAARAAYGCNYTN GCNMGNTGGAAYGARTGYAARAARACNGGNAARAARTTYAAYACNMGNAGYTCNAARMGN CARACNGTNGAYGAYAAYGAYGAYGAYYTNACNAGYAAYGGNAGYGGNAGYGTNATGGAR GAYGARATHTTYGAYGAYGARGARATHGAYGAYATGAGYGAYYTNTAYCCNGCNGCNGAY TTYGARGARGAYATHAARGGNGARATGAARGARGARGCNGAYGAYGAYGAYGAR------ ---------------ATGAARGARGARAAYGAYTCNACNCCNCARAAYATHTCNCCNAAR ACNYTNAARAARCARAAYGTNAARCARGGNAARACN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATHYTNACNTGYTTYMGNAAYYTNCAYMGNGCNMGNMGN GARGTNTTYACNGGNGAYGARMGNGCNYTNAAYGARGTNMGNAAYAARATHAAYACNGAR TTYMGNGARAARYTNGAYGARACNGAYGCNGCNAARATHGARGARAAYTTYGTNYTNGCN AARGAYGTNGCNTAYYTNYTNMGNTCNACNGTNATHCARYTNAARCARAARGAYGCNGAY GAYGARACNTAYGARYTNMGNATHACNAARGAYACNCAYYTNCCNGARAAYACNCCNTAY GAYCCNYTNAARGARATHCCNGTNAARCARMGNAARMGNAARGGNTCNCCNTGYTCNGAR AGYTCNAAYTCNMGNTTYYTNGTNAARGGNAARGARATGAARGARTTYTTYMGNYTNACN GARGAYTCNGTNATHAAYGAYTTYYTNAARATGGAYAGYTGYAARMGNATHGCNGAYAAR TAYYTNYTNGCNATGGTNTTYGCNTAYTTYAARMGNGCNGAYTTYGTNYTNAARGAYTAY ACNMGNATGAAYTTYTTYGTNGCNYTNTAYYTNGCNAAYGAYGTNGARGARGAYGARGAR GARYTNAARTAYGARATHYTNCCNTGGGCNYTNGGNAARGARTGGAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GGNCCNGAYGARTCN TTYTAYYTNCARCAYGCNGTNYTNAGYACNYTNMGNAAYYTNGCNATHCCNGCNGCNAAY AARCCNMGNYTNATGGARCAYAARGTNATGGARTCNTGYYTNTGYYTNGTNAAYTCNGAR GTNATGGCNGTNATHTTYAARYTNYTNGGNYTNYTNMGNATGYTNATHGARGGNCARGAR GCNGCNGCNGTNAARYTNGGNCARGARMGNGGNTTYYTNGAYTGYYTNTCNGARTGGTGY AAYGTNGARGTNCAYGCNGGNGTNAARGGNGARGCNCCNMGNGTNATHGCNTCNYTNATH AARAAYAGYMGNTCNYTNGCNGTNATHCARAAYYTNATHMGNGCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AGYGTNTAYTGY YTNGTNAAYACNGTNGARAGYCCNATHTCNMGNYTNTCNTCNACNTAYACNCCNAAYGAR YTNGARYTNTTYAARAARYTNATHGARTAYATHGTNGARTCNGARGAYGGNAARATHGGN TCNMGNATHGCNYTNAAYYTNACNGARAARYTNGARAARMGNATGGGNAARGARGARGCN CARAAYTTYTTYGAYAGYYTNGARAAYCARAARTGGATHGTNAARGAYGARAAYGGNAAR YTNTCNYTNTCNATHMGNTCNYTNYTNGARYTNGAYCARTAYYTNCARGAYATHTAYCCN ACNYTNATHAARAARTGYAAYYTNTGYGAYAARATHTGYATGCARGGNGAYTCNTGYACN ACNTGYGGNGTNMGNATHCAYYTNAARTGYTCNAARACNTAYTTYTCNAARCARACN--- GARMGNAARTGYCCNGTNTCNACNTGYMGNGCNCCNTGGAGYCARCCNGAYATHACNGTN CAYAARTAYACNMGNCARGCNAAYGGNAAYGTNMGNCAYCARTTYGTNMGNYTNYTNATH CARGTNAARYTNGARTGYTTYGAYCARCARTTYGARYTNACNACNAARTCNYTNCCNTTY TAYYTNTGYACNGGNGCNGTNCARGARYTNGARYTNATHGGNATGMGNATGTGGTAYTGY GCNAGYAAYGAYGAYATGTAYTCNCCNTGYMGNYTNAARAARGARYTNCCNGCNAAYGAR GTNTTYGAYTTYYTNGARAARMGNYTNCAR---TGYCAYTGYAARGARMGNATHYTNTCN AARGARGCNMGNCARCAYYTNATGTCNMGNYTNGGNAARTCNGGNTCNACNCCNYTNGAR MGNCARGCNATHACNGARAARGCNGTNAARGAYAARYTNYTNAARACNGAYGARAARGAR AARAGYTTYACNYTNTTYACNTGGTTYTAYGCNTTYGTNAAYAGYATHGARACNGARYTN TCNCARTAYTGGMGNGAYGGNATHATHTAYGAYYTNATGTCNTCNGAYGAYGCNGARCAR YTNYTNYTNCARGAYCAYATHCCNYTNTAYACNGCNYTNYTNMGNCCNGCNAAYCARTAY GTNCARAARCCNAAYTGYATHGAYGCNGTNATHAARYTNGCNGTNAGYATHAARTTYGAR GCNGARGAYGGNGTNAARATHGAYACNACNGCNATHAARATGAARGTNATHGAYMGNCAR GGNYTNAARGCNACNYTNGAYAAYATHCARTTY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN GAYGGNTAYAAYGGNACNYTNATGTGYTAYGGNCARACNGGNTCNGGNAARACNTTYACN ATGACNGGNGCNACNGARAGYTAYMGNCAYMGNGGNYTNATHCCNMGNGCNATHTCNCAR YTNTTYMGNCARGTNGARGAYMGNYTNGARAAYAGYATHAGYGTNMGNATHTCNTAYATG GARATHTAYAAYGARCARATGTTYGAYYTNYTNGGNAGYTTYCCNGARTCNAAYTGGGCN AAYAAY---AARGAYATHAGYAGYCARYTNGAYCCNATGGTNATHTCNGARAAYCARGGN GGNGTNTTYGTNAARGGNYTNTCNTGYCAYYTNGCNCARAAYGARGARGARGCNYTNAAY YTNYTNTTYGARGGNGARACNAAYMGNTCNATHGCNGCNCAYTCNYTNAAYAARCARTCN TCNMGNTCNCAYTGYATHTTYACNGTNTAYATHGARTCNMGNTCNMGNGTNCARTCNAAY GCNAARTAYACNGTNTCNAARYTNAAYTTYGTNGAYYTNGCNGGNTCNGARMGNYTNAGY AARACNAARTCNGARGGNAARACNAARGARGARGCNATGTAYATHAAYAARTCNYTNTCN TTYYTNGARCARGTNGTNGTNGCNYTNGCNGCNAARAGYMGNGAYCAYGTNCCNTTYMGN CARTCNAARYTNACNCAYTTYYTNAARGAYTCNATHGGNGGNCARTGYAAYACNGTNYTN ATHGCNAAYATGTGGGGNGARAARCARCARYTNGARGARACNGTNTCNACNYTNMGNTTY GCNACNMGNATGATGTGYGTNGCNAGYGARCCNGCNAARAAYGARATHTAYGAYCCNGCN YTNYTNGTNAARAARYTNCARAARGARATHAGYCAYYTNAARTCNGARYTNGCNATGCAY GAYACNYTNACNAAYMGNAGYATGGTNTCNTAYGAYGCNYTNTCNGARCARCARAARTAY GARATHMGNACNCARGTNMGNMGNTTYYTNGARGGNAGYYTNGAYGARATHGAYATHATH AAYATHMGNCARATHGTNGGNTGYTTYGARACNTTYMGNGARACNTAYCARGAYATGGAR MGNGARATGGARGCNAARYTNMGNGARAARTAYATGYTNATHGAYAARACNGAYCCNCAY TCNATHGCNGCNGCNCARCAR--------------------------------------- ------GCNGGNGTNCCNATHGCNGAYGAYGGNTCNTTYGTNGGNGARYTNGARGGNGGN GGNTTYGGNGTNGGNTCNGCNATHAARAAYTCNMGNACNGAYAGYTCNGCNGTNGTNCAR YTNAARAARAARGARMGNGARMGNGAYMGNAARMGNGGNTCNMGNGGNGCNAAYAGYCCN ATHGCNGGNAARTCNYTNTCNAGYCCNTCNCARAGYGTNMGNGGNGARMGNAARGCNGAR TCNCCNCCNACNCCNGTNGGNGARMGNGCNGAYAARGAYCARCAR------GARGGNTCN GCNTCNCCNGTNAGYTCNACNGGNAAYATHTCNMGNCAYGARMGNAGYCARMGNCCNMGN CAYNNNNNNGARNNNCCNNNNNNNGAYCCNCCNTCNGARGARMGNCCNGAYACNCCNCCN ACNMGNAGYGTNGCNTTYGARGARTTYAARGGNGAYMGNGGNAGYGARATHAAYMGNATH YTNATHGARAAYAARGARTAYYTNAGYACNTCNAARAARACNTAYTCNGAYYTNGCNAAR CARATHAAYAAYYTNAARATHAAYATHGAYCARTCNMGNCARAAYYTNGAYCARYTNAAR GTNCARMGNGARTCNGARGCNCCNATHATHAAYGARGARGGNGAYATHGTNATHAGYGAR GARGARTTYAARGARATHACNAARYTNMGNGARYTNAARACNYTNTAYMGNACNAARMGN GAYGARYTNGCNAARACNGARTCNGARGTNAARTAYTGYCARAARYTNGTNGAYCARTGY MGNYTNMGNYTNATHCARGARTTYGAYAAYTGGTAYAGYGARAGYTTYYTNACNGCNTCN GARGARAAYCARACNAGYYTNGGNGTNGGNAGYGGNGTNMGNCCNGGNGTNATGYTNCCN TTYACNGGNYTNGCNAAYGARGAYGARCARGARAARTTYGARMGNYTNCARYTNGARYTN ATGATGAAYAAYCCNGARTCNGCNGCNTTYTAYAAYGCNCARATGMGNACNGCNMGNMGN AARATHTAYGGNGCNGCNYTNACNCARCCNCARCCNGCNTTYMGNMGNCARGCNGGNACN CCNACNATGACNTTYMGNAAYCARCCNCCNGGNATHATGCARGTNCARTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CCNAGYGTNMGNCARYTNTCNGCNAARTTYGARTGGACNATHTAYGAY TAYTAYGAYAARYTNGARMGNGARGGNAARGGNYTNATHACNAGYACNGTNTCNGARCCN TTYTAYGTNGGNCARTTYGGNTAYMGNGTNTGYYTNGAYGCNTAYYTNAAYGGNAAYGGN CARCAYMGNGGN------ATGTCNYTNTTYYTNMGNGTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG GAYTTYGAYTCNTCNGCNAARTTYATHTCNTCNYTNTCNAARTTYYTNCARTCNYTNTGY AAYGGNTAYGTNGARTTYAGYGAYGGNGTNGARGTNATHGGNCAYATHTAYYTNAAYGTN GAYACNGGNAARAARATHGAYTAYGTNYTNAAYGARAARGTNTGYAARACNAAYGARAAY AGYGTNMGNTTYATHAGYAAYAGYTTYCAYGCNCARCCNGCNGARAARCCNAARCCNAAR CCNCCNCCNCCNCCNACNCCNCCNCCNCCNCCNCCNACNAAYCARGAYGAYGGNGARATH ATHYTNATGGARGAYACNGARAGYAARTCNAAYYTNTTYCARCCNCAYAAYTCNAAYTCN TCNAGYACNMGNCCNAARCCNCAYCAYTCNCARGGNGCNTCNAARMGNCCNCAYAGYCAR TCNTTYTCNTCNCAYMGN---GCNTCNAARGCNGCNMGNTAYTCNTCNTCNTCNATHMGN CCNAAYGTNCCNCCNCCNACNAAYGAYAGY------------------------------ AAYYTNTCNACNCCNACNGARTCNGARYTNTCNCAYYTNTCNCAYGTNTTYCCN------ ---------GAYAAYAAYGAYCCNGARCARAARGAYGTNYTNGAYAARGARATGAAYGTN GTNGAYATHAARCARGARTGYGAYCCNACNGTNGARCARGGNGGNGGNAAYAGYTAYGAR GAYCARCARGAYGCNTCNTAYTAYTCN------TTYCCNATH------TTYATHGTNGAY GCNTTYACNAARGTNGCNATGAGYGGNAAYCCNGCNGCNGTNTGYYTNGTNCCNCARGAY ACNACNYTNTGYGAYGAYGARATGCARAARATHGGNGCNGARATGAAYYTNTCNGARACN GCNTTY------GTNTGYAGYAARGAYGGNGAYTTYAARTCNAGYACNGAYTAYTCNYTN MGNTGGTTYACNCCNACNAAYGARGTNGAYYTNTGYGGNCAYGCNACNYTNGCNTCNGCN GCNGTNYTNTTYCARGAYGTNGGNAAYTCNAAYGARACNGTNGAYTTYCAYACNAARAGY GGNACNYTNTCNGTNACNCARAGYCARTCNAARCCNGGNTAYYTNGCNATGGAYYTNCCN AARAAYGARCCNYTNYTNCARAARATHGAYGARTTYCARGAYYTNYTNYTNAARTGYYTN GAYGAYYTNGAYATGGTNCAYGARGTNAGYTAYTCN---TCNACNACNAARAARYTNYTN GTNMGNYTNAARGAYGAYYTNAAYMGNTCNGTNYTNGARMGNYTNCARCCNAARAGYTCN GARYTNYTNGARGTNGAYACNCARGGNAARGTNAARGGNATHGGNYTNACNYTNMGNGGN TCNAARGCNAAYGGNTGYGTNGAYCCNGGNGGNAAYGTNTAYGAYTTYGTNTCNMGNTAY TTYGCNCCNTGGAAYGGNATHCCNGARGAYCCNGTNACNGGNTCNTGGCAYACNGTNGCN GGNCCNTAYTGGGCNAARCARYTNGAYAARCAYCARYTNTAYGCNMGNCARTGYTCNGCN MGNGGNGGNGAYYTNCARGTNGARATHAARGAYACNMGNGTNACNGTNATGGGNCARGCN GTNATHAAYYTNAARGGNGTNTTYTAYGTNATGGGNAGYAAYCCNAARAARCARTCNAAR TCNTTYAARGTNYTNCARTGGATGACNGARACNGARMGNGAYGARGAYACNACNGARGAR GARCCNAARGCNACNGGN---------------CCNAARAARCAYACNAAYCCNGAYYTN MGNCAYAAYGCNGAYGAYGAYGARATGMGNTTYACNGGNYTNCAYGGNAARGCNGAYATH CCNTCNAARACNTTYGAYATGYTNAARAARATH---------------ACNCCNGTNACN GARAAYGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG AARYTNATGGARCAYGGNTCNATHYTNAAYYTNGTNAAYYTNTAYAARACNGAYGCNAAR YTNATGGGNCARGTNGARGGNTTYGCNTGYYTNGCNACNATHGARYTNYTNCAYYTNTTY GARCARYTNCAYCARTGYGAYATHATHCAYGGNGAYATHAARCCNGAYAAYTTYYTNYTN AAYGAYYTNCCNAARGTNTGYGAYAGYAARGAYCCNMGNACNGTNTTYGGNTCNCARYTN CARYTNTTYTGYYTNATHGAYTTYGGNCARACNATHGAYATGCAYATGTTYCCNAARGGN ACNACNTTYAARACNAAYACNTGYACNAARGGNTTYGARTGYATHGARATGMGNACNAAY AARCCNTGGACNTAYCARACNGAYYTNTTYGGNYTNGCNGGNACNATHCAYGTNYTNYTN TTYGGNTCNTAYATGAARGTNTTYGTNGARAARGGNACNTGGAARACNACNGGNAGYTTY GTNMGNAARTGGAAYGTNCCNYTNTGGAARAARYTNTTYCARGARYTNYTNAAYATHCCN TCNTGYGAYCAYYTNCCNAAYYTNGCNYTNYTNMGNGCNGARTTYGARGARTAYTTYTGY TCNAGYYTNATHTCNTCNTAYAAYGAYTGGGTNAAYAARGTNAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYCARGAYYTNATHAAR TTYTTYCCNCARGTNAAYAARTTYATHCAYAARGCNMGNATGGARGGNGGNGGNGTNYTN GTNCAYTGYYTNGCNGGNGTNTCNMGNAGYGTNACNGTNACNGCNGCNTAYATHATGACN GTNACNGARYTNGGNTGGMGNGAYGCNYTNAAYGCNATHMGNGGNAAYMGNAGYGTNGCN AAYCCNAAYTAYGGNTTYCARAARCARYTNCARGTNTAYGAYTCNGARCARGTNGTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GCNAGYCARGCNGCNGTNMGNGARATGAARGARGARACNGGNTAYGAYGTN CARGTNGTNGAYATHTCNCCNAGYACNTCNYTNGAYCCNGGNGTNGGNAAYACNACNYTN AARATHGCNACNTGYAARGTNGAYGTNAAYYTNAGYAAR---GARGARMGNCCNAARCCN ACNGGNGGNGAYTCNGAYGARTTYGTNCARGTNATHGTNCARCCNATGGARACNYTNACN GAYAARYTNAARGARTTYGAYGCNAGYGGNGAYTGYGTNGAYTCNMGNGTNTTYACNTGG GCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GTNATHTTYMGNATHAAYGAYAAYGGNYTNGGNCCNGAYYTN YTNCARCARGTNTTYYTNGARMGNGGNTGGGTNGARTTYGAYGARGARGTNCAYAAYCCN GARGARTGGAAYYTNTGGTGGMGNACNTCNMGNTTYMGNCARGGNGARTAYAGYAAYYTN YTNCCNTGGCARCAYATHAAYCAYTTYCCNAGYTGYACNATHYTNACNAARAARGAYGCN YTNTGYMGNAAYYTNMGNAARATGACNATHATHCAYGGNYTNAAYGTNTAYAAYTTYAGY CCNAARGCNTTYAAYYTNCCNAAYGAYTAYACNAARTTYGTNTCNGARTAYGCNGCNTGY MGNCARACNTCNAARAARGAYACNCCNCCNGTNATGTGGATHTGYAARCCNGCNGARTCN TCNMGNGGNMGNGGNATHTTYATHTTYMGNGARYTNTCNGARYTNCARTAYGAYTGYAAY GCNGTNGTNCARCARTAYATHAAYGAYCCNYTNYTNATHGGNGGNTAYAARTTYGAYATH MGNATHTAYGTNACNATHCCNAGYTAYCAYCCNYTNCARATHTAYATHCAYGARGARGGN YTNGTNMGNTTYAGYACNGARAARTAYGAYYTNGAYMGNYTNGAYAAYGTNTTYGCNCAY YTNACNAAYACNAGYATHAAYAARTTYAGYCCNGCNTAYACNGCNGARAARGARGARGTN GGNCAYGGNTGYAARTGGACNATHTCNCARYTNMGNMGNTAYTTYYTNCARAAYAAYATH GARGAYGCNMGNATHTGGCARCARATHACNAAYATHGTNATGTTYACNATHYTNATGCAR GCNCCNACNGCNCCNAARCAYGCNAAYTGYTTYGARYTNTAYGGNTTYGAYATHYTNATH GAYAGYTCNYTNAARGCNTGGYTNYTNGARGTNAAYTTYAGYCCNGCNYTNAGYTCNGAY TGYCARGCNGAYATHATHGCNAARAARGGNATGYTNCAYGAYYTNATGTCNYTNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GGNACNMGNTTYYTNAARMGNGGNATHAAYCAYGAR GGNTAYGTNGCNAAYGARATHGARACNGARCARATHGTNCARGAYACNTCNGTNACNAAY YTNGAYAARGGNAARATHTCNTCNTTYGTNCARYTNMGNGGNTCNGTNCCNYTNTTYTGG TCNCARGAYATHTCNAARATGGTNCCNAARCCNCCNATHGGNYTNGAYCARMGNGAYCCN TAYTGYAGYGCNGCNGGNGTNCAYTTYAAYCARATGYTNTAYMGNTAYGGNTCNCCNATH ATHGCNTTYAAYYTNGTNAARACNMGNGARAARAARMGNCAYGARAGYATHYTNAGYGAR GAYTAYGTNAAYACNATHGAYTAYYTNAAYCARTTYYTNCCNGCNGARCAYCAYATGCAR TAYATHGGNTTYGAYATGGCNMGNGTNAAYAARMGNAARGAYGCNGAYGTNATGYTNMGN YTNAAYMGNATHGCNMGNTAYTGYYTNMGNCARACNGGNTTYTTYYTNMGNGTNCARTCN CCNCARGCNGARTAYYTNYTNAARGAYAGYGARYTNCARAGYYTNAARGGNATGTGGGGN GGNAAYGGNATGMGNCARACNGGNGCNGTNMGNACNAAYTGYGTNGAYTGYYTNGAYMGN ACNAAYACNGCNCARTTYGCNATGGGNMGNTGYGCNYTNGCNTAYCARYTNTAYGCNATG GGNATGATGGARMGNCCNCARYTNGARTTYGAYACNGAYTGYGTNAARYTNYTNGARGAR YTNTAYGARGAYCAYGGNGAYACNYTNGCNYTNCARTAYGGNGGNAGYCARYTNGTNCAY MGNATHAARACNTAYMGNAARATHGCNCCNTGGACNTCNCAYAGYMGNGAYATHATGCAR ACNYTNTCNMGNTAYTAYAGYAAYGCNTTYTCNGAYYTNGARAARCARCARGCNTTYAAY YTNTTYYTNGGNGTNTAYATHCCNCARGAYGGNCARCCNAAYYTNTGGGAYYTNCCNACN GAYTTYTAYYTNCAYAAYYTNTCNTCNYTNGGNAARMGNATHACNAARCCNAAYTAYTGY CARTGGTGGGAYTCNGARGTNTGGGARACNYTNCCNYTNCCNMGNGAYGARGTNAAYAAR TCNCARGTNGTNCAYGCNGCNATGYTNACNACNAAYCARMGNGAYGARCAYGTNAAYTCN TTYTAYGARCAYTAYMGNCCNGARGARYTNTCNGTNTTYGAYGARATGTAYCARATGTAY YTNTCNCARGCNTGYTGGAARCAYYTNCCNAARCAYGCNAAYGAYTTYAGYCCNTTYTGY GTNMGNCAYCAYGCNGARACNATHGARTCNAAYCCNAGYATHTCNGGNAARGAYTCNACN TCNTCNACNACNTCNTTYGGNTCNGARGGNAARAARGTNCCNCCNGGNGTNGAYATHTTY CCNATHTCNGTNTTYAARYTNGAYAGYACNTTYTAYGTNGARCCNCCNCCNGTNAGYMGN CARGCNAARGAYATHTAYACNGCNTAYGTNAAYMGNGGNTAYYTNGGNGCNCARACNGTN TCNGAYGARAAYATHMGNGCNTAYATHAARTAYMGNGARGARATGYTNGCNYTNTAYAGY GARCAYTAYGCNGCNCCNGARCARGTNMGNAARCAYCARGCNATHTTYTCNAARGAYAAY CARMGNCCNATHTCNYTNAAYCCNTTYTCNGARGAYGARCARMGNYTNATHTCNCARGGN ATHAAYAGYCAYATHGTNYTNMGNGGNGGNMGNGGNGGNATHTCNGAYMGNGGNMGNGGN MGNGGNMGNGGNMGNGGNCCNCCNGARTTYGAYGCNMGNCCNCARAARMGNGAYGAYGAY CARMGNGGNCCNMGNAARATHAGYGAYTCNTAYGARAAYGTNCCNGARTGGGCNGCNGAY GAYGTNGGNGAYGAYCCNGGNACNTTYGAYTCNAARGGNGTNTTYGTNTCNAAYMGNATG AARATHGCNGARTCNGARAAYYTNYTNMGNATGGARAARTCNYTNCARAAYYTNATHGCN GGNATGAAYGCNAAYACNGARACNAARGCNGARGARGARATHGAYGTNTCNACNGGNGCN YTNCCNYTNTCNCAYAARGAYGCNAAYAARTGGTTYTAYMGNGAYCCNCARGGNCARATH CARGGNCCNTTYAAYAGYGARAGYATGGCNGARTGGTTYAARATHGGNTAYTTYACNATG AGYYTNATHGTNAARMGNGGNTGYGAYGAYTCNTTYAARCCNYTNGGNGARYTNATHAAR CARTAYGGNMGNGTNCCNTTYGGNCCNGGNCCNCCNYTNCCNCCNATHATHACNACNAGY CARCCNGARGARGTNGTNCCNCCNGARGTNCCNGTNACNCCNCCNGTNATGACNATGCCN TCNYTNGTNTCNCCNATGATGCCNGGNGGNCAYGAYMGNTTYYTNTTYMGNTCNATGATG YTNCARGARCARCARCARCARCARCARCARCARCARCARCAYMGNCCNTTYCCNATHTCN CAYCCNTCNATGTCNATGCAYAAYGTNAAYACNACNACNYTNCARAAYAGYACNAGYACN GTNTGGGCNAAYTCNCARCAYACNGARAGYATHTGGTCNCARCCNTCNTCNATGTGGGAY ATHGAYAAYACNAGYGARACN---TCNCARGCNTAYAARATHCARATGGARAARYTNAAR MGNGARMGNGARGARGARAGYCARMGN---GARGARMGNATHCARCARGARYTNYTNGAR AAYAARCARAARGARATHMGNYTNCARCARAAYGARYTNGARAARCARMGNGARCARGTN MGNMGNGARAARGARGARYTNGARMGNGARMGNYTNMGNAARATGGARGARGTNMGNAAR ------------------------GARGARGARMGNYTNYTNCARYTNGARATHGARMGN AARGARAARGARMGNATGGARCARGAYACNMGNAARGARGAYMGNAARAARMGNGARCAR GARYTNAARAARCARGARGAYAARMGNMGNAARGARGARGARAARYTNATGYTNGARGAR MGNAARMGNCARGARGARGCNMGN---------CAYAARAARGARCARGARGARATGMGN MGNMGNGCNGARYTNGARGCNATHCARAARGARGARYTNMGNMGNGARAARCARATHCAR GARGARGARGARMGNATGCARMGNGARGCNGTNGARAARGAYAAR--------------- ------------------------------------CARYTNGCNACNATHAARAARCAR CARATHGARTTYCARMGNCARCARGARTCNYTNMGNAARYTNCARCARGCNCARAARGAR CARYTNGCNAAYATHCARYTNCCNGCNTCNAGYAAYTGGGCNAAYAAYGGNTCN---CAR GGNGGNGCNGTNCAYTCNAARTCNYTNACNGARATHCARGTNGARGARGCNATGAARGAR AARGARMGNCARMGNGARGTNCARYTNCARMGNGARMGNATGCARGARCARGCNGTNGTN ATHCARCARCARCARAAYCARAARACNTGGGCNACNGGNGCNMGNGGNGCNCCNGGNMGN GGNYTNTCNYTNYTNGARATHCARAAYCARGARAARGARAAYGCNAARAARTCNGAYAAR GGNAARCCNCAR---AAYCAYCARGCNAARCCNAGYYTNGGNAGYGGNGGNAAYTTYYTN GGNTCNGCNGGNCCNGGNYTNTGGGGNACNAAYACNAAYTGGGARGGNAAYGCNTCNCCN GCNTCNACNACNAGYATHTGGGAYATGGGNGTNCCN------------------------ ------------CARTCNATHAARAARCCNCARYTNGGNAARAAYAGYYTNGGNAGYGGN CARAAYGCNCARTCNAARAARAAYAGYAARACNAAYAARAARGCNGCNGCNCCNTCNGTN AARGARGTNGARACNGTNCARAARYTNTTYCARAAYAARAARCARGAYGGNTTYTCNGCN TGGGTNTCNGAYAARYTNTCNAARTTYTCNTCNAAYATHGAYGTNCCNACNTTYGTNTCN TTYATHGTNGAYGTNGAYAGYCCNGAYGAYGTNYTNGAYTAYGTNAARACNTAYYTNGGN GAYAAYAARGARACNCAYGAYTTYACNTAYCARTTYYTNGARAARMGNAAYCARTAYAAR AAYCARATGMGNYTNCARAARCARYTNGARGARGAYAGYATHTGGGGNCCNGCNCCNGCN ATHAAYCCNCAYAGYCCNCCNACNTTYGARGCNTCNAARTCNGCNGGNGARAGYGGNCAR GTNAARTCNAARGGNAARAARAARAARAARGCNCARAARYTNGAYGTNAGYATHYTNGGN TTYACNGTNCAYGCNGAYCCNAAYMGNAARAAYGCNGGNGARYTNGARACN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARTTYAAYTAYACNAARCARAARAARGARYTNGCNGARGARMGNMGNMGNGAR TAYAAYGARYTNYTNCARCARAARGCNAAYCCNGTNAAYAARGARMGNGARCCNGARATH GAYAAYCCNTCNATHATHCCNTTYAAYMGNCCNGAYCARGARMGNYTNAARGTNAARATH YTNGARGARGARMGNCARMGNGARTAYAAYCAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TCNTCN MGNTCNTCNGAYGGNMGNGARACNCCNATGATGTCNGCNTCNTCNGAYMGNATHTCNAAR GCNTTYGARGTNTCNGAYCARGTNGARTCNATGAGYCARCARYTNAAYGTNAAYAARTTY GAYGAYGTNTGYGCNCAYYTNMGNTCNACNYTNGARTCNGARGTNGAYCARYTNYTNGCN GAYATHGARTTYYTNCARTGYTGYYTNGAYGARGARGCNGAYATHMGNGAYTGYATHGAR ACNCCNMGNATHTCNMGNGARCCNACNYTNACNGARYTNMGNGARGARMGNACNTCNYTN GARAARGARYTNYTNYTNTCNGAYAAYYTNACNTTYACNCCNCARGTNGAYAARCCNGCN TTYAAYGAYACNYTNATHAARYTNGCNCCNACNCAYCCNTCNACNACNTCNGTNATHYTN ACNCARAARCAYAGYCCNGTNAARGCNAAYCAYCARATHGCNACNTCNACNGARATHTGY AAYAARGCNAAYGARGARTAYGTNCARGARAAYTAYCARAARGCNGTNGAYYTNTAYACN GARGCNYTNGCNGTNGAYGGNAARMGNGAYGAYATHTAYTGYTTYMGNGCNCARGCNTAY YTNTCNYTNGGNAAYACNACNGCNGCNATHAARGAYTGYGAYGAYGCNATHAARATHAAY CCNCARAAYCARAARGCNTAYYTNAARAARGGNTCNGTNYTNYTNAARATGGAYGARGTN YTNCARGCNGARAGYATHYTNAARGARGGNCARAARCARTGYTCNAGYGARAARGAYTTY YTNGARTGGATHTGYAARGTNGARAGYMGNATGAARGARYTNGGNATHMGNCARAAYCAR CCN---------------------------------------YTNGCNGCNYTNAARTAY AAYTGGTAYCARACNCAYACNCAYGTNATHGTNAAYGTNATGGTNAARAAYGTNAARAAR GARGARYTNAAYYTNGAYGTNGARGARMGNYTNTGYAAYGTNAGYATHMGNGGNGAYCAR TGYAGYCARGTN------AAYATHCCNYTNGCNCAYAGYATHGTNCCNGARCARACNCAR TCNAARYTNTTYGGNACNAARATHGARGTNAARYTNAARAARTCNGARGGNATHCARTGG ACNAARYTNGARGGNCCNAARGARGARGARGAY---ACNATHYTNCCNCCNTGYGCNGCN CCNGTN---GARGTNGARACNCCNAGYTAYCCNAGYTCNTCNCARCARCCNMGNGAYTGG GAYAARYTNGCNGCNGARGTNACNGARGARGARAARAAYGARAARYTNGARGGNGAYGCN GCNYTNAAYCARTTYTTYCARAARATHTAYGCNGAYGCNTCNGAYGARACNAARMGNGCN ATGATGAARTCNTTYTCNGARTCNGGNGGNACNGTNYTNAGYACNAAYTGGAAYGARGTN GGNGARAARAARGTNGARGTNAARCCNCCNGAYGGNATGGARTAYAARAARTGGGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNATHAAYGAYMGNYTNMGNCARGGNAARYTNAARMGNAARGAY YTNTTYGTNACNACNAARATHCCNMGNGCNAGYCAYAARGCNATHGAYGTNTAYAAYTGY GTNMGNAAYTCNYTNGARGAYYTNCARYTNTCNTCNGTNGAYATGYTNYTNATHCAYACN CCNTGGAAYGGNGARYTNGAYATHYTNCARYTNTGGMGNGCNYTNGARAGYYTNCARYTN AARGGNYTNACNAARAGYATHGGNGTNTCNAAYTTYACNATHGARCARATHAGYTCNGTN YTNGARATHCARAARGTNCCNYTNGCNAAYGTNCARYTNGARGCNCAYATHTAYAAYCAR CARAARAAYYTNAARCARTTYTGYGAYTGGAAYGAYATHGTNGTNTCNGCNTAYTCNCCN YTNGGNTCNGCNGGNMGNGCNAGYMGNGTNGTNGARGGNACNGGNACNYTNATGAARGAY CCNYTNATHGTNAARYTNTCNCARTCNTAYAARAARACNCCNGCNCARATHYTNYTNAAY TTYYTNYTNTGYTGYGGNATGGTNGTNATHCCNAARAGYAAYAARCARGARMGNATHAAR GARAAYTTYGAYTGYTTYGAYTGGTGYYTNAGYCCNTCNGAYTTYCARGCNATHCARGCN YTNGAYAAYGGNGTNAARTTYTTYCARTTYYTNTAYYTNACNCARCAYCCNGAYTAYTTY AARGGNAARGARTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ AARYTNYTNAGYACNAARCARCCNATHGTNGARGCNGAYYTNATHMGNTGYYTNGCNTGY AARGCNYTNGCNGGNATGTCNMGNTCNGARACNATHMGNCAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARGAYYTNAAYAARGAYMGNACNAGYCCNGTNGARYTNTAYYTNGAY ATGGCNACNYTNYTNTCNGAYCAYAARCARYTNGTNGARGAYTTYGCNGGNTTYYTNYTN TCNTTYCARGCNATHGARTGYCARTGYYTNTCNACNACNCAYCARTAYACNCARATHMGN MGNTTYYTNMGNCARATHGARGTNAAYTGYGGNAARTCNGTNAAY---YTNTAYCARAAR GCNYTNAARTCNATGTCNAAYTGGTCNGAYGTNTGYCARMGNGGNGARYTNGCNGGNAGY YTNAARAARCCNYTNATGAAYGTNYTNAARAAYGTNCCNGARGTNYTNGAYGAYYTNGTN GGNTAYTTYYTNGAYGGNCARGTNCCNGCNAGYGCNAGYGAYGAYTTYGARGARGTNGTN YTNGAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARGTNYTNCAR YTNGCNMGNTCNGARAGYAAYTTYAAYTTYATHACNGGNAAYGGNGCNTCNYTNYTNCAY AARGCNTGYTAYCARGAYAGYGTNCCNATGGTNGARYTNYTNYTNACNGGNGGNGCNAAY GTNAAYTGYGCNGAYGAYGAYTGGTGGACNCCNYTNCAYATHGCNTGYTAYCAYGAYAAY CAYGAYATHGTNCARYTNYTNYTNAARAAYGGNGCNGAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CCNACNAARATHCAYGGNYTNGARAARTGYMGNATHTGYAARCARMGNGCNTCNAAR GARGARMGNATGAARGAYATGYTNATHMGNTGYGCNYTNTGYTAYAARGTNGGNCAYATG AGYTGYYTNGAYYTNACNGAYGARYTNGTNGCNGTNATHMGNACNTAYCCNTGGCARTGY ATGGARTGYAARACNTGYGTNCARTGYATGGAYCCNTAYGAYGARGAYAARATGATGTTY TGYGAYMGNTGYGAYMGNGGNTAYCAYACNTTYTGYATHGGNYTNGAYGCNYTNCCNACN GGNCAYTGGGARTGYMGNAGYTGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATHGGNCCNGCNTAY CCNGGNTTYGAYTAYAAYACNMGNAARGGNGCNGTNGCNGCNCCNGTNACNTAYAARAAY ATHCARTTYAAYGCNTAYTAYGARGGNGGNGGNYTNTTYYTNCCNAARTAYGCNTCNCAR AARGARAGYCARGTN------YTNGGNCAYTAYAARTCNYTNGAYGAYACNCCNGCNGCN ATHGTNAARTGYMGNTGYGGNAARGGNACNGTNYTNYTNTCNGGNYTNCAYATHGARTAY TCNTCNAAYACNYTNGAYCCNGARAAYCARTAYYTNAARAARATHYTNCCNACNYTNATH CAYAGYGARAARAGYMGNAARTAYGTNTTYMGNGAYGTNYTNAARAARYTNGGNATHACN TGY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARCCNTTYACNTTYGGNTCNACNTCNTCNGCNCCNATHGGNAGYGGNTTYAAR TTYTCNACNACNGCNYTNTCNGTNTCNGCNTCNCCNTTYTCNYTN---------GGNACN ACNACNACNGCNGCNGGNTTYTCNTTYGGNGGNATHTCNTCNTCNTCNACNTCNACNACN GCNCCNACNGCNACNACNGCNGCNAGYGGNTTYTCNTCNTCNACNACNGCNACNACNGGN ------------------GTNAGYGGNTTYTCNTTYGGNGCNYTNGCNGCNAARGCNATG ACNCARAAYTCNCARAGYGAYAAYAAYGGN------AARGGNGGNGARGAYGAYGARTAY GTNCCNCCNAARCCNGARGTNAARGARATHACNGARGARGGNTCNYTNYTNTCNAARMGN TGYAARYTNTTYTAYCARAARGARGGNCARTGGACNGARMGNGGNGTNGGNAAYGTNCAY GTNAARCCNYTNGAYAAYGAYAARACNCARYTNYTNATHMGNGCNGAYACNAAYYTNGGN AAYATHYTNYTNAAYATHAAYGTNACNGCNGCNYTNCCNGTNTCNMGNCARGGNAARAAY AAYGTNGTNYTNGTNTGYGTNCCNAAYCCNCCNYTN------------AAYGARAARGAY AARGAYCCNAARCCNATHTCNATGYTNATHMGNGTNAARACNGGNGAYGARGCNGAYGAR YTNYTNGCNAARYTNGAYGARMGNAARGARYTNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNATGMGNTGYMGNYTNGCNGGNTGGATGGAY GAYYTNMGNGAYAARATHATGAARGARATGGARAARGCNYTNTGYGAYTCNAAYCARTGY CARAARGAYGARTTYAARAARACNACNAARTGYTAYGTNTCNGARAARAGYTCNYTNAAR AARGARGTNAAYAAYYTNACNGARMGNYTNAAYGAYYTNGARTGYAGYYTNGGNCARAAR AAYACNYTNGTNAARAAYATGACNGAYAAYATHTGYTGYCARAARAARAARYTNGAYCAR GCNAARTGYTTYTAYGCNTGGAARACNGARTGYGCNGAYAARGAYMGNGARTGYTTYACN GARAARYTNGCNGCNGARCAYCAYAAYAARAARYTNGCNCARGGNGTNYTNAARGCNTGG CAYGGNGTNATHCARTCNAARTGGMGNTGYMGNGTNGARMGNCARTGYCARACNCARGCN AARAGYYTNTGYATGAAYYTNAGYACNGAYTAYGARGTNAARGTNTGYATGYTNAAYGAR AARATHCARTCNYTNGARGARAARGTNTGYYTNYTNCARCARGARMGNGARATGTAYTCN GARCARGTNAARAARGCNTTYATGMGNGGNATGTGYGCNYTNAAYGTNGARACNATGTCN ATHYTNACNGARGCNGAY------------------GGNTGYCARGAYCARCCN------ ------MGNTCNATGCCNCCNTCNAAYACNTAYGARGARGARGTNACNTAYTCNAAYACN CARCCNGTNTCNMGNGTNCCNTCNAARAGYYTNCCNAAYGGNTCNTCNCARACNGGNYTN MGNACNACNTGYTCNGTNCCNGTNAARTGYMGNMGNMGNCARCARMGNYTNCARYTNGCN ACNTGYYTNMGNMGNAARGTNCCNAAYAARAAYYTNYTNAARGGNAARAARGCNAARGGN GGNAARGGNAARGGNAARTCNGGNGGNAARAAYAARACNGGNAAYGCNTCNGTNCCN--- ------------------------YTNGCNCCNCCNATGGCNTCNGTNGTNGTNGARMGN CAYCCNTCNATHAAYAARCARACNYTNGGNAARGCNACNGCNGTNMGNTAYCCNAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGAGYTCN GAYATHTGYTAYAARTGYGGNGGNMGNGGNCAYTTYGCNMGNGAYTGYMGNAAYGGNGGN CCNCCNGGNCCNGGNCCNCARMGNTTYTCNGGNGGN---------------------TTY TCNGGNGGNCARAARTGYTAYAARTGYAGYMGNATHGGNCAYTTYGCNMGNGARTGYACN CARGAYCARGARMGNTGYTAYAARTGYAAYGGNTTYGGNCAYATHGCNAARGAYTGYGAY AARGCNATHTCN---ACNGGNGCNTGYTAYAAYTGYGGNAGYGCNGAYCAYYTNCARMGN GAYTGYCCNGARGCNATHGTNAARTCNTGYTAYMGNTGYGGNGARTCNGGNCAYYTNGCN AARGARTGYCCNGCNGAYATHCCN------------AAYAARCCNTTYGCNGAYGAYMGN AARTGYTAYACNTGYGGNGGNGTNGGNCAYYTNTCNAARGAYTGYCCN------------ TCNCCNMGNMGNGARTGYTAYMGNTGYAAYCARACNGGNCAYGTNCARAARGAYTGYCCN AAYTCNCCNCARTCNAAYACNACNTGYTAYAAYTGYAAYGARACNGGNCAYATHGCNMGN GAYTGYACNGCNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GGNMGNATHGAYAARCARGARATHMGNGAYGARATH CARTCNCARATHGARYTNTTYACNAARYTNGTNGGNMGNGTNCCNAAYTAYGTNGAYGGN CAYCARCAYATHCAYGTNCAYCCNGCNGTNGCNGAYATHTTYGCNTCNACNYTNCARGAY TAYAAYATHCARGCNACNMGNTAYCCNGTNGARATGTTYYTNGAYAARAARACNGGNATH CAYCCNYTNTCNATGGARTTYTAYAAYAARATGATGGARGAYGCNGARGCNTGYAARTCN ATHTTYGAYGTNCAYGAYATHMGNTAYTCNGAYGCNTTYGTNGGNYTNTCNACNATGGGN TCNAAYATGACNACNCARMGNYTNCARTCNGCNYTNYTNGAYGCNTTYCAYGARGTNGAR AAYAAYTGYGAYGCN---TCNAARMGNTAYYTNACNTGYGARYTNATGACNCAYCCNGGN TAYGCNACNGGNAARAGYAGYGGNGGNTTYGAYTGGNNNTCNGAYGAYTTYGGNTGYTCN ACNGAYMGNGARCAYGARATHCARGTNYTNACNTCNACNGARATGYTNGAYTTYTAYACN CARAAYAAYATHCAYYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNATGMGNCARTCNCARCAR GARMGNMGNATHGCNGTNCARYTNYTNCARGCNMGNMGNGARAARGARGTNATHMGNCAR AAYMGNATHYTNMGNGARAARCARTAYCARGARMGNMGNCARAARGAYTTYGARGAYGCN YTNGAYYTNGARGCNGARATGTCNGCNYTNCAYAARYTNGARTAYGCNGARCARATHAAR MGNGAYCARGARYTNCAYGAYCARATHGCNGCNCARMGNGCNGARCARAARTAYAARAAY CAYTAYGAYATGTGYGGNGARATGGTNGGNAGYATHYTNGAYTTYTCNTGYAARATHGCN GARTAYMGNGARYTNACNTCNAAYYTNYTNCCNCCNAARYTNATGMGNGARTGGAARYTN YTNTTYACNAGYGGNCARCCNYTNTTYGARAARGTNGARGARGTNAGYAGYGARYTNACN CCNGARCARGTNYTNGARGARGAYMGNCARCARYTNYTNGAYGARGGNGAYTTYATGGAR TAYAARGGNATGACNGGNGAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GCNCAYTTYMGNATHTCNGCNAARGARACNGGNGGNCAR TGGGCNYTNAARATHGTNGGNGCNGAYCAYAAYCAYATHGAYCAY------GAYGGNTCN AAYGCNTCNYTNCAYCCNGARAAYMGNMGNCCNGARYTNACNGARACNATHAARGCNATG ATHGCNTCNGGNGTNTCNACNTCNCARYTNMGNACNTAYATHMGNGAYTCNCARCARAAR AAYGTNYTNCCNAARGAYATHGARAAY------------------------ATHYTNMGN MGNYTNMGNCCNTTYACN---TCNAAYYTNATHAGYAARAAYGGNAARCCNATHCAYACN ACNCCNAARAARTAYGGNGARGCNYTNTAYMGNGARAARATG------TTYGARTAYAAR GARCCNMGNTAYATGCARYTNGCNGGNACNGCNTTYAGYGCNTTYYTNTGGTAYTGGATH YTNTAYCAYTGYTAYTTYGARTAYGARCAYYTNGTN------------------------ ---------------------------------------------TTYYTNAAYAARYTN GGNGARATHCCNGTNATHAAYGAYGGNTGGTTYAARGCNGCNGAYTAYTAYTCNMGNGCN AARGARTAYAAYGCNYTNATGMGNYTNACNYTNTCNYTNGCNGARTCNAGYGTNAARAAR GCNGGNGARYTNTCNGCNCCNGTNYTNCARCAYTAYAARCCNCAYATHGAYAAYATHGAY GAYTAYGCNTGYAARAARYTNGAYCARYTNGARTCNAARTAYCCNTGYATHAARCARCCN ACNGARCARTGGAARGARAGYTGY---------GTNGAYCCNGTNYTNGGNMGNGTNAAR CCNGTNATHTCNCARGTNCARGGNATHATHGAYAAYGGNAARCARACNATHAAYACNATH AARACNACNAGYACNGGNATGGTNGARAARGCNAARTCNACNGGNGTNGAYACNGCNACN TAYGTNTTYAAYGCNAGYTTYGARACNTAYCCNGGNMGNATGGTNACNMGNACNGTNGAY GGNGCNATHGGNATHGCNGARAAYYTNGTNGAYAARTAYYTNCCNGAR------GARGAR ACNGAYGAYTGYAARGAYGAYGAYATGTCNGAYGCNAGYAGYGAY--------------- ------ACNAGYGGNGTNGARCARATGGAYGTNATGGAYCCNTCNCCNAARMGNGTNTTY GTNCAYGCNAGYTGYGTNACNGARAARYTNMGNAARMGNATGTAYAARMGNGCNGTNAAR GAYYTNACNTAYGCNMGNTCNMGNACNACNACNGCNYTNAAYMGNATGAARGGNGCNGTN GAYYTNGCNGAYTAYGCNAARTCNAAYATHACNGTNGCNAARGAYAARGTNGAYCAYATG TGGAAYGARATGATHACN------------------GARAGYGCNGARGARAARACNGTN TTYGTNGGNGGNGTNGARGAYMGNATHATHGCNYTNGGNCARYTNGTNGCNMGNCARGTN AARTCNGGNATHAARGARTTYGAYMGNGCNTGYGCNGARATHGTNGARTTYAARAARGAY CCNATHTCNAARTCNAARGARTAYAARGARYTNATHGGNACNTTYYTNTCNGTNGAYTCN YTNAARAAYYTNACNTCNCARAGYATHACNAARGCNMGNGARTCNGTNAAYYTNATHCAR GARMGNATHCARAGYATHTCNAARYTNTAYCCNAGYYTNAGYTGGGTNACNGTNGAYATH AAYATGGARGAYATHCCNYTNAGYGARTCNGAYYTN------------------------ ------------------------ACNTGGCCNYTNYTNTCNMGNAAYYTNGTNMGNGTN GGNGTNGAYGTNTTYACNAARATHTTYMGNGARATGCCNACNYTNMGNAARYTNTTYGAR CAYTTY---GAYATHAAYGAYATHAAYAAYYTNGAYAGYCAYAAYGARTTYMGNGARCAY GCNCARMGNTTYATGTTYGTNATHGARAGYATGGTNCARCAYYTNGARCAYCCNGARGTN ATHCARGCNCAYYTNGTNGCNYTNGGNGCNMGNCAYGTNACNGTNGARGGNTAYCAYCCN GARTAYTTYMGNTTYTAYATHAARTGYATGYTNGARGTNTGGGARGTNGARYTNGGNGAR GARTTYATHATHGARGTNMGNGARAGYTGGACNAARGTNTTYGARTAYATHATHMGNTGY ATGTCNCAYGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNAARCAYGCNGTNMGNTGYTTYACNAGYTCNGTNGCNATGACNGARGGN YTNGARTCNAARATGGGNATHGARATHGCNTCNYTNTGYCCNGAYGCNGCNAAYACNGAY YTNATGACNAARYTNGAYGARACNATGATH------------GGNGAYTTYGARMGNGTN ATGGCNCARGTNTAYGARMGNATHYTNCCNGTNTCNGAYGTNGTNGAYGCNTTYTTYACN YTNYTNGARAAYGARAAR---ATGAAYGGNGCNATHYTNTTYGTNACNMGNGCNGGNAAR AAYTAYCARAARATGGARMGNGTNGAYYTNGGNCCNGTNTGGCCNATHCCN------GGN AARGTNTGYACNGAYACNTCNCARTGYGARAARGGNGARTGYTGYCARATHATGAGYGAR TTYATGATHGTNTCNAARMGNGAY------------YTNGTNGCNACNYTNCCNACNYTN ACNAARACNGGNACNTGYGARAARTAYMGNYTNGARGGNGAYAAYTGYGGNACNTAYGAR AARYTNAAYGGNTAYTGYGGNTGYGARCCNGGNACNCAYTGYAARTCNGARGARATH--- ---------CCNATHGGNGARTCNAARMGNAAYATHGCNGCNCCNMGNCCNGGNTAYCAR TGGAARATHACNTGYACNAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GCNGCNGTNGCNTTYGTNATGYTNYTNATHYTNATHAGY ATGATHGTNTTYGCNGTNTGYTAYTCNTCNTGGGTNMGNTCNAAYATGAARCARGAYGGN AARGTNAARATGCCNAARTCNTAYTTYMGNAARAARAARGARGCNAARMGNMGNATHYTN GARGCNATHCCNAARCCNGCNYTNTCNAAYGGNATHGCNGGNGTNCCNCCNGTNACNGTN GTNGAYAARGAY------------------CARATGGTNCARGGNTGGAAYCARCAR--- ---------ACNTCNCCNTAYGARATHAARGCNTTYAGYATHGARYTNGGNGARGARAAY GAYGARGARTTYCARATHGARACNACNYTNGTNGAYAAYGARGTNYTNGAYGTNGGNCCN TTYAARAAYATG---GAR---CCNAGYGCNMGNCCNGTNGAYGGNAAYGTNTAYAAYAAY CCNTAYATHTAYAGYAAYAAYGAYMGN---------------------------ACNMGN ACNATGGCNAARYTNATGCARAARACNGAYGCNTCNAGYYTNYTNGCNGAYGTNGAYAAY TTYYTNTTYGAYTGYGAYGGNGTNYTNTGGGARGGNAAYGGNCCNATHGARGGNAGYYTN GAYACNATHYTNAARYTNAARCARYTNGGNAARAARGTNTAYTAYGTNACNAAYAAYAGY TCNMGNACNMGNCARGAYTGYGTNGAYAARTGYYTNTCNCAYGGNTTYCCNGCNGARYTN GAYGAYATHATGTGYACNGCNTAYATGGCNGCNCARTAYYTNAARATGAARGGNTTYCAR GGNAARGTNTAYYTNATGGGNMGNGARGARAGYATGGGNAARGARYTNAARGARGTNGGN ATHCCNTAYATHGGNCCNGGNYTNGAYCCNTAYGARTGY---AGYACNTGYGAYTGYATG AAYACNGARYTNGAYCCNGARGTNAAYTGYGTNYTNGTNGGNTTYGAYCCNTAYATHAGY TAYYTNAARATHTGYAARGCNGCNAGYTAYYTNAARAAYCCNGAYTGYATGTTYYTNGCN ACNAAYGARGAYCCNTGYYTNCCNATGAARGGNAARATHMGNATHCCNGGNACNGGNACN ATGGTNGCNGCNGTNAARACNCCNTCNGARMGNGAYCCNATHGTNGTNGGNAARCCNGAR ATGGGNATGTTYGARGTNYTNCARACNACNCARAARTTYGAYGCNTCNMGNAGYYTNATG GTNGGNGAYMGNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYTAYGAYCCNGCNGARCCNACNGAR GAYGARGAR------GAYAARAAYGCNGGNGGN---TCNAAYYTNTAYTGYCAYGTNTGY AGYGTNTCNGTNTAYGAYGARGARAGYYTNAARMGNCAYYTNAAYGGNYTNAARCAYAAR GCNMGNATGGARAGYATHGCNAAYGTNCAYGCNATGMGNTCNCCNCARYTNAAYCCNMGN YTNCARGCNGARGARCAYYTNMGNAAYATHGARMGNAARGGNGGNMGNAAYCCNGAYTTY TTYTGYAARATHTGYAAYAAYGARYTNACNATHCCNTGGGARAARCAYMGNTAYTCNAAY ATHCAYAARCARMGNCAYYTNCARGTNMGNAARGGNTGYGGNTGGTGYAARGTNCAYGAY TTYAAYAAYTTYACNGARGTNYTNGARCAYMGNGARACNGARGARCAYMGNAARAAYTCN CARATGTAYGGNAARAARGARGARGARAAR---------------------GAYGAYGGN AAYMGNAARMGNYTNAARGAYGGNAARGARGGNGARGARGAYGAR--------------- ------------------AAYGTNGARGARGARGAYYTNACNATHCCNGARTAYAAYCCN GARGTNCCNGTNGGNYTNGAYTAYGTNATHCCNGTNACNGGNTAYTTYTGYAARYTNTGY CAYAARTTYTAYAAYAARAARTCNGCNMGNGCNGCNCAYTGYYTNAGYGARGTNCAYTAY GCNAARTTYAARGARGCNACNGARGCNAARATHGCNGCNAARGARAARMGNGARGARGAR GCNMGNYTNMGNAARGARGCNAARGARGCNGARGCNAAR--------------------- ---------------------------GARAAYGGN------GARGARGARAAYGARGAR GARAAYGTNGAYGARAAYATGGARGARGGNGGNGAYGARGARGARGARGTNAARGARGAR GARAARGARGCNACNGARGARGTNGAYGCNATHYTNGARGARGARGARATGGAYGGNGAY GTNACNGAYCCNGGNCARGAYGGNTCNATGGTNGAYGGNACNGTNGAYACNTCNAGYTTY GTN--------------------------------------------------------- ------------------------------------------------------MGNYTN AARCARATHTGGACNAGYAARATGCCNGTNCARGGNGCNYTNYTNACNTAYMGNGARCAY YTNYTNTGYYTNGGNGAYAARATGTAYAARATGGGNGTNGAYMGNACNGARGCNGCNYTN YTNTGYGCNATHAGYATGACNAGYATHGAYTGYCCNGGNYTNYTNAARACNACNACNGTN ACNGARGTNCARAGYGTNYTNATHGAYGCNYTNGARGCNCAYACNGTNCARTCNMGNTCN CARGGNMGNCAYCARACNYTNYTNGGNYTNATGCCNCARGTNMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GAYGAYMGNYTNAAYCARYTNGCNGCNGTNYTNAAYACNAARAARCARCCNTCNTTYGAR GCNAGYAAYGAYTCN---------------GTNACNYTNAARAGYTTYTAYYTNTCNGTN TTY---GAYGGNTCNTAYYTNTCNCARAAYGCNTCNGAYCAYTCNCAYATHTCNTCNYTN ATHAARCARTAYGARCARTCNGARGGNMGNCARATHACNGARATHGTNCAYCARAGYAAR TCNAARGGNGGNGGNGCNGGNCARGARGCNTAYGARAARACNGARYTNAARCAYGGNGAY AARATGTTYCAYMGNTTYGCNAARGARYTNCARAARTTYCCNCARCARTGYATHMGNTAY GARTGGGGNGGNCAYCCNYTNYTNATHMGNCARYTNGAY---CAYYTNGARGTNATHCCN ATHTGYACNMGNTGYGGNGCNGTNMGNGTNTTYGARYTNCARYTNGTNCCNGCNYTNATH CCNAGYYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GCNGCNGCNGAR CAYATGAARGAYCCNGTNTTYMGNGCNTTYYTNGGNTAYGGNACNGTNGTNATHGCNAAR ACNATGYTNATGAGYTTYYTNACNGCNMGNCARMGNATHTCNAARAARGTNTTYGCNTCN GARGARGAYGTNGCNTAYTTYAAYAGYAARAARCCN------GCNTTYACNATH---GAY ---CARGAYATHGARMGNATHMGNMGNGCNCAYYTNAAYGAYATGGARTGYATHATHCCN TTYGTNYTNYTNGGNYTNYTNTAYACNGCNACNGGNCCNGAYYTNAGYACNGCNYTNYTN CAYTTYMGNGTNTTYACNGGNGCNMGNATHYTNCAYACNATHGTNTAYYTNGCNAARGTN CCNCARCCNGCNMGNGCNATHACNTAYTTYGTNGGNCARATHATHAAYTTYTCNYTNGTN TAYCARATHATHAARCARGCNGCNTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GTN CAYTGYGCNGGNYTNTAYGAYGCNGCNYTNATHGARGAYYTNTGGMGNAAYATHATHGGN AARGARATHAGYAGYACNTCNCARATGTCNGGNTCNGAYMGNATHAAYACNATHGGNACN AARATHTCNACNATHGCNAARACNTAYATHAGYGCNGARMGNTAYTTYCCNATHGCNATH ATHYTNMGNCAYYTNGARCARAARTCNTGYGARYTNTCNATHGAYGTNGARTGGGTNTTY AARATGYTNYTNGAYGTNGGNGTNGCNCCNGCNMGNYTNYTNGARYTNTAYGAYMGNYTN TAYAARTCNAARGAYGTNGTNTGGMGNACNYTNAAYCARCCNYTNCAYGTNYTNATGGTN YTNCAYGCNTTYATHGAYCAYYTNGCNAARAAYCCNGTNYTNYTNAARACNGCNAGYCCN CCNATGCAYGTN---TGGTGYYTNGAYYTNYTNGCNTCNTAYYTNGTNGAYYTNGGNGCN YTNGGNACNTCNACNMGNGAYGTNGCNCCNYTNGTNACNGGNTTYAARGCNACNAARGCN MGNYTNGARMGNYTN------GAYAGYYTNMGNCARTAYCARGAYGGNGAYGGNGARGTN GAYYTNTCNCARTTYACNCCNACNACNCCNAGYCCNGARGARGTNAAYTGYGARGTNGAR ATHCCNGTNACNMGNMGNATHGGNGGNAARTGYATHAAYATGGGNAAYTTYAAYGGNTGY CARGCNGGNGTNTAYYTNGCNTTYGAYCCNAAYTGYTAYATHCAYGCNACNACN------ ---------------ACNACNTCNTCNCCNYTNYTNAAYAAYMGNMGNCAR--------- MGNCAYMGNMGNAAYGTNCARYTNCARGAYGGNTAYATHAARNNNAAYACNTAYGGNACN TGYYTNTGYNNNYTNNNNGAYCCNGGNTAYCCNNNNGGNACNTTYGCNYTNGARNNNNNN NNNNNNNNNNNNNNNNNNNNNGTNAAYNNNNNNNNNNNNGCNGGNATHTTYAANNNNNNN NNNNNNCARNNNTAYGANTGYNNNNNNACNNNNNNNYTNGGNNNNGGNNNNCCNTCNYTN NNNTTYCCNNNNTCNTAYGGNCCNNNNNNNNNNGANNNNNNNNNNATHNNNGAYNNNNNN NNNNNNNNNNNNNNNTGYNNNNNNAARNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN ATHNNNNNNNNNNNNNNNAAYNNNNNNGTNCANNNNNNNTAYNNNNNNNNNNNNNNNNNN NNNYTNAANNNNNNNNNNNNNNNNNNNNNNNNNTTYNNNTTYTAYNNNNNNGGNTCNGGN NNNNNNATNNNNAARTGYGTNGCNACNAAYCCNYTNTTYCCNGARNNNNNNNNN---TCN AANNNNNNNATHGARNNNNNNGCNCCNCCNCCNNNNCCNCCNGTNTTYATHATHGANGGN AARNNNATHTCNCCNNNNNNNGCN---TCNNNNGTNNNNNNNNNNAAYGGNMGNGAYGTN AGYNNNNNNTGYNNNGTNNNNGGNGGNTAYCCNNNNGTNNNNGTNAARGTNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATHACNCCNMGNATHACNCCNTCNYTN GAYNNNGTNNNNTGYNNNTGYNNNGCNNNNCAYGARNNNNNNTGYTAYACNAARACNACN GTNAARGAYTTYCAYGTNCCNATHACNYTNGARGARGGNMGNGCNAARGTNMGNGARGTN TTYYTNAARAAYAARCAYGTNACNGAYATHMGNGTNATHGAYATGYTNGTNATHAARGGN CARATGGARYTNGTNGARACNGCNAAYATHTGGAARCARAARCAYCAYGTNATGATGTAY TTYAARGAYACNGTNAAYCCNAARCCNACNGAYTTYYTNAGYAARTTYTAYGARGGNCAR GARGAYYTNAGYGARTCNTCNATHGARTGYYTNYTNGARCARYTNACNGARMGNGGNGTN ATHAARAARGCNATHGTNATGGAYYTNGARGGNCAYGTNGTNGCNMGNACNMGNATGTCN GTNAAYAAYCAYYTNGCNTGYTTYTAYGAYAGYYTNMGNGGNCAYTAYACNGGNYTNATG AARATHACNGAYCARGAYGAYGTNTAYACNTGYTTYAARTGGCCNTCNTCNGCNATGYTN GTNGCNAAYTCNACNAARTGGGTNTCNGTNGCN---------------GTNATGCAYGCN AGYGAYAAYYTNTAYAARMGNATG---------------TAYAARGAYAAYCARATGGAY CARGARTTYGAYCAYAARGTNAARAARGTNTCNGAYAARTTYTCNGARACNGTNAAYATG ATHGCNAAYGARCCNTCNYTNGCNTTYTTYMGNATHCARGARCAYGTNMGNAARACNYTN CCNCARYTNGTNGAYACNAARCAYGARGTNGARGGNYTNCARTCNAARGTNCARGGNTCN TGYTTYGAYACNGAYTAYGCNATHAAYGCNGTNAARGCNATGCARAGYAGYGCNATHCAY TTYGARAAYATHCARGAYYTNYTNAARAAYGCNATGTAYATGAARCARCARATHTCNTAY GARGARAAYAARMGNAARCARGARMGNAGYAGYTCNATHGTNGGNGCNGCN--------- YTNCCNCCNTGYMGNATHTGYYTNGCNCCNGGNGCNGGNTTYCAYTAYGGNGTNAAYACN TGYGARGCNTGYAARGGNTTYTTYCAYMGNAGYYTNAAYCAYTGGACNAARTAYAARTGY ATGAAYAARGCNMGNTGYGTNATHYTNCAYGGNAAYGGNAARATGTGYMGNAARTGYMGN TAYGARAARTGYYTNGARATGGGNATGTCNAARGCNGCNATHAARACNGGNMGNTAYAAY TAYAARAARAARACNGAYGAYATHYTNGARGTNAARYTNATH------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TAYATHMGNGTN AARAAYMGNGCNGAYGGNAARGARAAYGAYGARCCNGTNGAYCCNGAYGARGAYGTNGAR CCNATHCCNTCNGAYACNATGAARTCNGCNGARAAYYTNAARMGNAARGARMGNGGNAAR TCNMGNAARAGYCARAAYCCNMGNMGNCAYCCNCARGTNAAYGARAARGAYTAYGAYACN TTYGARATGGARGTNGARGARATHGAYGARGCNGARAAYGGNAGYGARCARGAYMGNGAY ATHTAYCCNTCNTCNGCNGAYAAYTCNGTNAAYATGTAYAARAGYTCNCAYATGCARYTN ATHCCNTCNYTNGARGAYAAYAGYTTYACNGCNACNACNACNCAYTTYGCNMGNACNCCN GTNMGNACNGGNMGNYTNCCNACNCCNAAYMGNGGNGGNTTYACNAAYMGNTCNACNAGY GCNTCNAGYYTNTAYTGGAGYTGYGGNTAYTGYGAYTTYCARAGYAGYAGYCARGCNGAR ATHAARGARCAYTCNAAYMGNACNCAYCCNGGNAARCCNCAYMGNTAYGTNGCNYTNATH AARAAYATGAAYCCNGAYTCNATHATHAAYAARAAYAARAAYAAYGAYTAYAGYGGNTTY AARCCNTCNCCNTCNACNCARMGNGAYAGYTCNCCNTAYAAYAARAGYTCNTTYTCNTCN GTNAARYTNGAYAGYGTNGCNGGNAARTTYGCNGGNGGNGAYGAYGTNGTNTCNYTNAAR AAYGARGCNGAYGAY---AGYATGYTNAARGTNAARTTYGGNGCNTCNAARGTNAARAAR GARGCNACNACNTAYAARTGYTAYCAYTGYACNTAYACNGCNAARMGNCAYTCNTCNATG AARTCNCAYATHTAYTAYAARCAYMGNGGNAARGGNYTNYTNGCNGTNGAYGARGAY--- ---ACNGCNAAYCARGTNTTYTTYTGYGCNMGNGAYGAYTGYACNTTYAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AAYGARTGY GGNGARGGNGGNGARTAYGARACNTTYGTNTAYGAYTGYCCNYTNTTYAARAARTCNATH YTNATHGARAAYAARGARYTNGTNATHCAYTCNGAYGAYGCNTTYGCNCCNGTNGGNTAY YTNAAYYTNAARAAYTGYMGNYTNGTNGAYAARCCNGGNTTYGAYGTNAGYGAYATHTCN AARCAYATHTCNCARYTNCCNYTNTCNACNACNTCNAARTGGYTNTCNAARCAYATHACN GCNGCNGAYAGYYTNGAYGTNGAYAAYAGYCCNGGNGGN---------CCNGAYGCNTCN AGYCARGARAAYATHTCNYTNGCNGGNGAYGARGTNCARCCNGTNTTYACNGAYGGNTCN MGNATGTAYGTNTCNGGNYTNAARGCNATGGCNGCNGAYACNGCNGAYGTNGCNGARGCN ACNACNACNGCNATGGAYAARYTNAARGARGGNGTNGARMGNYTNGGNTTYCARATGTCN GAYYTNGTNTAYATHTCNYTNTAYGTNGGNAAYATGTCNAAYTAYGCNTCNATHAAYTCN GTNTAYAARAARTAYTTYACNYTNAAYCCNCCNACNMGNATHTGYYTNAARYTNCCNYTN CCNTCNAAYGTNYTNTTYCARYTNGAYTGYCARGGNMGNACNGARGARGAYAARGAYMGN MGNACNATGTAYGTNCARAGYYTNTCNYTNTGGGCNCCNGCNAAYYTNGGNCCNTTYAGY CARACNATHATGGARGGNCARGARYTNTAYGTNTCNGGNACNACNGCNATHATHCCNTCN ACNYTNAARYTNATHCCNGCNGGNATHGARGCNCARAGYAARGTNGCNYTNATHCAYYTN YTNGARAARYTNGTNGCNGTNTGGTCNGCNTGYACNYTNTCNCAYTGYCCNYTNGTNTAY TGYTTYGTNAAYAARMGNCARTAYATHCCNGTNGTNMGNAARTCNTTYGARAAYATGYTN AARGARAAYAARAGYYTNATHCCNGGNGTNGAYYTNCARCCNATGGTNCARTAYAGYGTN GTNCCNGGNATGCCNCARGGNGCNYTNGTNGARTGGCARACNTGYGCNTGG--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARGAYGAYYTNAAYMGN GTNTGYMGNYTNGARGGNCARYTNAGYGGNGCNCARATGGARYTNGARAARYTNGARAAR CARCARGTNAAYYTNGTNCARGARATHGCNATHGARATHGAYGCNYTNGTNGARACNGCN TCNGTNGAYGCNACNACNMGNTGYCARCCNATHAAYGGNYTNAARAAYYTNGCNACNGTN MGNTCNGGNATHCCNAAYCAYYTNYTNACNGARATHAARAAYAARYTNAARTGGYTNMGN TCNGARTTYMGNGARMGNYTNGCNAARGARMGNMGNYTNMGNGGNGARTTYMGNACNGCN YTNTCNTCNAAYGARGCNGAYMGNCARTTYYTNATHGGNCARYTNGCNMGNAARGAYGAR GARYTNGAYGAYYTNGCNYTNGARAARCARGAYYTNTCNTTYAARGARATGCARTCNCAR AAYATHGTNGAYGTNYTNGARGAYCARGTNTTYGAYYTNTCNGAYGARYTNCAYYTNMGN AARATHMGNGARGAYGARCARMGNAARATGTTYGTNMGNGARAARCARAAYATHATHGTN GARATGGARGAYATHATGGAYGCNGARAARCARAARGCNAARATHGARGAYMGNTAYMGN MGNYTNCARGAYACNYTNAARTCNYTNCAYCAYGAYYTNAAYACNACNAARYTNGARAAR GCNAARAARACNAAYGGNATHYTNMGNACNMGNACNCCNAARGGNACNCCNAARAARMGN AAYCAYGTNMGNATHTCNCCNACNACNCCNACNAARGARTTYGAYGCNGAYGARCCNATH YTNMGNAGYCCNTGYMGNACNCCNCCNCCNATGACNYTNACNGAYGAYGARTTYMGNTCN AARTTYYTNACNGAYACNCCN---------CCNTTYCARCAYGCNAARGTNGGNTCNTTY YTNCARACNAARCCNGAYYTNMGNAAYCARTAYAARGARGAYACNTTYYTNMGNGGNTAY YTNCARMGNCAYGTNCAYAAYGARTAYYTNCCNGARATGGARTCNGAYYTNTCNMGNTTY GGNGAYMGNGTNGCNGGNGAYYTNTTYCARYTNTCNGTNCARATGGARGTNGARAARCCN MGNYTNGARCARTAYGAYGCNTGGGGNCAYMGNGTNGAYMGNYTNGTNACNTCNAGYGCN TGGCARAARATGAARGARGTNTCNGCNGARGARGGNYTNGTNGCNTCNGGNTAYGARMGN CARTTYGGNGARTGGAGYMGNYTNTAYCARTTYTGYAARTTYTAYYTNTTYGARCCNTCN GCNGGNYTNTAYACNTGYCCNYTNGCNATGACNAAYGGNGCNGCNMGNACNYTNGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATHAARTCNCCNTCNTCNGGNYTNMGNYTNGGNYTNTCN MGNAAYCARMGNGTNAARCCNYTNCAYTCNTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATHAARTAYGGN GGNAGYGCNAAYGGNCAYMGNGGNGTNYTNTCNTGYACNTCNTGYTTYAARTCN------ ---------------GGNGGNYTNTGGCCNAARGAY------GAYTCNGARATGYTNMGN MGNYTNMGNATHGGNATHGGNMGNCCNTCNTCNAARTCNGARGTNGTNTCNTAYGTNYTN GAYYTNTTYTCNGARCAYGARMGNAGYGCNGTNTAYTCNGGNATHGAYAARGGNYTNGAR YTNYTNATGAARCAYATHGARGARMGNATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AAYAAYAAYAAYAAYGCNGAYATHGARACNCCN YTNTCNAAYTGGTTYGCNGARGTNGTNGARYTNMGNMGNMGNGCNAAYGARTAYMGNAAR MGNGCNCARGGNACNCAYTTYTCNMGNGARCAYYTNGTNCARYTNATGGCNCARCARGCN GAYTGYTGGGAYGTNGAYTCNCARACNTCNTCNACNATHMGNGCNYTNAAYYTNGAR--- ------------------------------------------------CCNGCNMGNATH GCNAAYMGNGTNGTNCARGAR------AARGAYATHTCNCCNGTNYTNTCNGAYATHGAR GAYYTNGARGARGARAARGARGARAARGTNAARCARAARTCNACNAARAARAAYTAYAAR GCNGCNTCNTCNGARGGNMGNAARGCNAARMGNYTNGARGARGAYAARAARGCNGTNTCN CARCARCARAGYAARATGAAYGTNCARGCNAAYMGNGARAARGCNGCNYTNGGNGARGAY GAYGAYGTNGAYGAYATHGARGAYGAYGARGGNMGNCARCCNACNCCNAARYTNAARCAR ACNAARTCNTAYGCNTCNMGNCAYCAYYTNGAYYTNACNACNCCNGCNGTNGGNGGNGCN YTNYTNACNTGYCCNCCNCCNAARGCNAGYAARATGATHGTNACNTCNMGNTCNGGNGAY AGYTAYGTNACNGCNTCNGAYAAYACNGARATHATHCARGAYAAYYTNAARTTYGAYATG GARAARYTNAARACNMGNCCNATHYTNGGNCARCCNTCNGGNGAYACNCAYGCNYTNMGN GAYGAYGAYGCNTCNACNGAYMGNGCNYTNAAYACNMGNTAYGTNCCNTCNCCNGCNTAY ATHACNTCNGARGAYGAYAARGARAAYGCNCCNTCNGTNAARGGNAGYAAYAARCCNCAR AAYCCNTGYMGNYTNACNCCNGTNCARGARGGNGCNGGNAARACNTTYGTNAARTCNAAR CCNTAYYTNACNYTNGCNGAYATHAARGGNAAYGARATGAAYCARATGGAYGAYGAYGTN ATGTCNGTNTCNATGATGTCNGTNGCNTCNAGYGCNTCNYTNGCNTCNGARGTNYTNGAR MGNGCNAARAARMGNCARAARGARTTYTGGGGNAARGGNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNGAYGTNATHYTNGAYGAYGGNACNATGTGYAARTGYMGNACNTAYGARCAR YTNGARAAYGTNCCNAAYGAYGAYAARAARCCNCAYCCNTTYTAYAARAARATHGTNATG GARGGNGCNMGNMGNCAYGGNTTYCCNAGYGAYTAYATHCARTTYYTNGARAGYTTYGAR GAYAGYGGNGARATHGARGTNGCNTCNACNTAYAARTCNYTNATHCCNGTN--------- ---AARCARTGGYTNCAYCCNTCNAAYGCNYTNACNAARGGNCAYATHYTNTAYACNGTN AARTTYYTNGGNGARTGYAARGTNGARCARCCNAARGGNACNGAYGTNGTNAARGCNGCN ATHACNAARATGAARTTYAAYAARCAYATHAARMGNGCNGARGGNCARAARCCNCCNAAR GTNGARYTNACNATHTCNGCNGAYGCNGTNAARATHYTNGAYCCNAARAAYAARATGATH YTNCAYCARTAYCCNYTNCAYMGNATHTCNTAYTGYGCNGAYGAYAARTCNGAYAARMGN ATGTTYACNTTYATHGGNAARGCNGCNGAYAAYAAYGAYCAYTTYTGYTAYGTNTTYGAY AGYGARAARTGYGCNGARGARATHACNYTNACNATHGGNCARGCNTTYGARYTNGCNTAY AARMGNTTYATHGARGCNTCNACNCARGAYACNGAYATHMGNAARCARTTYYTNGCNYTN CARCARMGNACNAAYACNYTNCARTAYGARAAYGAYGTNYTNAARAARMGNYTNGCNGAY YTNGARAARYTNAARGAYMGNTCNGAYGTNGARCARTAYAARATHAAYAAYGARATHAGY GAYATHACNACNGTNAARYTNAAYYTNMGNGARAGYTCNACNGAYGARGARGAYAGYCCN GTNMGNAAY---GAYCCNAGYGAYMGNGCNAAYGTNGTNGGNMGNMGNYTNGARAAYYTN GTNTTYGCNGARGAYGGNAAYAARACNACNAAYGGNAAYCAYGCNCCNGTNTTYAAYTCN TTYAAYAAYTCNAAYTCNTCNACN------------------CCNATHYTNAGYCCNCCN CCNCCNAAYTCNMGNCARTCNMGNAAYTCN------GTNAAYGCNACNAAYMGNATGAAY GCNYTNAAYAGYGCNAAYAAYAAYAAYGCNGGNTTYGGNAGYCARTCN------------ AAYCAYACNGAYGCNTTYGGNATGGCNGARTTYAAYCCN---ACNCCNCARTCNCARCAR GARYTNATGGAYATHCARGAYGGNTTYAAYMGNGGNYTNTCNTTYGGNACNGAYGAYTTY AAYATHGAYGAYYTNGAYCCNYTNAAYCARMGNYTNATGGGNAAYTCNAAYMGNAARMGN MGNACNMGNTTYTCNTGYGGNCAYYTNGGNMGNACNAARACNTCNGARYTNTGYCCNAAR TGYAGYMGN---------------MGNGAYTCNCCNGCNTCNTCNTCNAARCAYAARMGN AAYAARAGYGTNYTNGGNGGNGARATGGAYTCNAARCAYTTYTCNTCNMGNTCNACNACN GAYAAYYTNCCNAGYTCNYTNAGYACNCCNGGNGARMGNGCNGGNYTNGCNTCNGCNTCN CCNACNACNGTNGAYACNTCNGTNGCNACNTCNTCNACNAAYACNCCNCAYYTNTCNAGY ACNTGYGCNACNTCNGCNCARACNGARATHACNTCNCAYGCNACNAAYACNGTNACNGCN GCNYTNGARGCNGARACNGAYACNACNMGNYTNCCNCCNGAYGCNACNGAYTCNCCNTCN GTNCAYTCNGAYACNAGYGAYAARACNTAYGAYCCNAARAAYGAY---CCNAAYTTYTGY TCNTCNTCNAAYTCNAGYYTNTCNGAYYTN---------------------------TCN GCNGTNATHTCNTCNACNAARGTNCARACNGAYGAYYTNYTNGAYACNGARYTNGGNYTN TCNAGYACNGAYGGNGTNAGYYTNTCNCCNCCNTCNAARAAYTCNATHTCNYTNTCNAGY AAYAAYGGN---------CARAAYGTNATHGTNGAYACNGCNGCNATHGGNACNGGNAGY GTNTCNGGNACNTCNAAYAARGAYAAYACNTCNTCNATHTCNGARMGNYTNGARGAY--- GGNTGYAARGAYAAYGTNTCNTCNTCNCCNAAYCCNTCNGGNTCNAAYATHYTNAAYGAY GCNAARCCNTCNATHGCNGAYGCNTCNCCNCARTCNACNACNCCNMGNGGNACNAARMGN ACNCAYGGNGARATHGARAGYACNAGYGARGARAGYTCNAAYTCNAARCCNTCNCCNCAR AARAAYAARAARMGNTGYTAYATHTGYAGYTGYAARYTNGARYTNGCNCARMGNACNATH GGNAARTGYMGNTGYGAYCAYGTNTTYTGYCCNACNCAYMGNYTNCCNGARYTNCAYGAY TGYGTNTTYAAYCAYAARGARGAYGGNMGNMGNGARGCNMGNGARAARATGGTNAARCCN ACNMGNCAYATGGGNACNTCNTTYMGNMGNGAYYTNTGYGARAARGARAARGAYGAYTAY GTNAAYGAYGCNATHCARAARGARYTNMGNTAYGGNMGNGGNCCNTAYGTNATHAAYGGN GTNCCNATHTCNMGNGGNATHCARGGNTGYTGYAAYYTNGAYCCNTGYTTYTGYMGNTCN GAYGTNATHTTYTAYGAYGGNATHGCNTAYGAYCARAARCCNTTYATHGARGGNGGNYTN MGNACNMGNCCNGGNAAYGTNATGTTYTAYGARGGNAARATGGCNGGNCCNTTYAAYCCN GGNAARTCNCCNYTNATHTAYGGNCCNAAYMGNAAYMGNGAYAARCCNCCNCARMGNAAY TGYTTYGARACNGTNAARACNGGNCAYGGNTAYMGNCAYTGYTGYACNACNTCNATHTAY GGNGAYAARGTNCCNCCNTAYCAYAAYACNCAYAARYTNGCNTAYACNAARYTNGGNYTN CCNCAYGGNAAYACNATHGGNTAYTTYMGNTTYAARCCNCARMGNATHTGYTAYAAYMGN CARMGNCCNGTNCARMGNTAYGARGAYTGYTGYGAYTGYCARCCNAGYGCNTAYGAYGCN AGYCARTAYGTNAAYGAYGARTGYCCNGGNAARACNTGYTGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYGARMGNATGTCNGAY GAYGAYGAYGAYTCNGAYGCNGARTCNTGGGAYAGYTAYGAYGAYAAYGTNYTNGGNYTN GARGARTGYGTNTTYTGYTCNTTYATHAGYCARTCNATGGARGAYAAYYTNTCNCAYATG ACNACNGAYCAYGGNTTYTTYYTNCCNGAYGCNGARTAYYTNTGYGAYYTNGARGGNYTN ATHGCNTAYYTNGAYGARAARGTNGGNGCNGGNCAYGTNTGYYTNTGGTGYAAYGARAAR GGNAARMGNTTYCAYAAYACNAARGAYGTNCARMGNCAYATGGTNGAYAARGGNCAYTGY AARATGYTNCAYATHCCNGARACNATHTAYGARTTYGCNGAYTTYTAYGAYTAYTCNAAR AGYTAYCCN------AGYGCNGARGGNTCNTCNACNGAYCCNGCN---GAYCCNGTNGAY ATHACNGARYTNGAYGGNGAYGGNTAYTCNYTNACNYTNCCNTCNGGNGCNGTNATHGGN CAYMGNTCNYTNATGCARTAYTAYMGNCARAAYYTNGTNCCNCARYTNMGNGARMGNACN MGNGAYGTNYTNCCNAARATGYTNGCNCARTAYAARGCNYTNGGNTGGACNGGNGCNACN GGNATGGCNGTNCARCARMGNGCNAARGAYYTNCARTAYATGCARMGNGTNMGNAAYCAR CAYTTYATGAARGTNGGNGTNAARGCNAAYAGYYTNMGNYTNMGNYTNMGNCARCARAAY ------------------------------------------------------------ ---------MGNAAYCARGARATHYTNYTNTCNTGYYTNTTYATGGARGGNGTNGGNAAR TTYGCNYTNGTNATGGARAARGARTTYAARATHCAYYTNATHCARACNYTNTAYCCNYTN ATHGARAAYYTNGGNCAYGARAAYACNCAYATHAGYAGYACNGCNTAYGAYACNYTNACN CARATHTGYACNGCNTGYGGNTAYAGYTCNATHGAYGTNYTNATHCARGCNAAYGCNGAY TAYYTNATHAAYAGYGTNTCNYTNMGNYTNMGNCAYTTYGAYCARAAYCARMGNACNCCN MGNYTNYTNTGYGTNATGTTYAARTAYTGYTCNCARGAYYTNYTNCCNYTNGTNTAYCAY AGYATHGGNGARATHYTNGAYTCNYTNGAYGAYCAYTAYACNGARGAYGTNGTNYTNTTY ATGCCNGTNYTNYTNGARYTNGTNAGYGCNGTNGGNMGNTGGTTYCCNTCNACNCARAAR GTNAARCARGAYACNGAR------------------------CARAARCARTCNGTNGTN TCNTTYYTNGARGARTAYATGAARYTNAARMGNACNGCNGARATG--------------- GARATHGTNGAYAAYGAYATHAAYGGNAGYGARAARTCNYTNGARAARATHGARGARGAR TTYGAYAARYTNAARAARGARAARMGNGARCARGARGARAAYGARGAYGTNGARGAYGAR ---------------------------GARAARCARAARGARCCNCCNCARCAYGTNMGN GTNGTNAARGARGTNYTNGCNMGNATHAARAAYYTNYTNGCNTCNAAYGAYGCNMGNATH MGNGTNCARGCNYTNGARATHGTNGCNCARAGYTGYMGNGAYYTNGCNGGNCAYGARMGN GAYYTNYTNCCNCARYTNCAYCARATHTGGCCNAGYTTYTAYCCNMGNTTYCAYAGYGAR GARAARTTYGTNGTNATHAARGCNYTNCAYACNYTNCARGTNATGGCNGAYGTNGGNGGN AAYTTYGTNCARCARMGNGTNATGAARGAYGCNATHCCNGGNYTNTCNCARTTYATGGAR AARCARGCNAARATHAGYGGNAAYAGYTCNGGNGTNTAYATHCAYACNCCNAGYTTYAAR YTNCARYTNGCNGTNYTNAAYACNTCNGGNYTNYTNGCNGARAARYTNGARATGAARGAY MGNAAYYTNGAYYTNATGGCNAARATGTGYYTNCCNTAYYTNAAYTCNCAYCARCCNYTN CAYYTNCARACNGCNTGYGTNAARACNTTYGCNTCNTTYATHCAYYTNGAYCCNGAYGCN ATGTGGYTNGTNYTNTGYMGNYTNTAYTGYCCNTGGGARTAYAARGTNCCNAGYCCNAAR TTYAARCCNYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARMGNAARGCNAARGCNMGNGAYYTNGARCARGAR MGNATGGARGTNAGYGTNMGNATHGAYGAYACNCARTAYGTNAAYGTNGGNAAYTCNAAR MGNTGGCARTGYAARGARTGYGAYAARTCNTAYACNACNAARCAYAAYYTNGTNATGCAY GTNYTNGAYCAYAGYGGNATHAARCCNCAYYTNTGYYTNAARTGYGGNAARTAYTTYAAR CARYTNAGYCAYYTNAAYACNGGNMGNMGNGGNMGNGTNMGNAARAARTCNGCNAARGTN YTNGARATGGARGARTTYGARCARGCNGARAARACNACNACNACNAARAARGGNAARACN CCNAARTCNAARCCNCCNAGYGTNGARAARATHAARAARAARTCNACNGCNGARYTNACN CCNATGGARGCNYTNGCNCARGCNYTNATGCCNGAYATHAARCARGARATHAARCCNGAY ATHGTNCCNATHGCNGAYGTNATHCCNTCNAGYATHCCNCCNCCNGTNGTNAARGARGAY CARGARAGYGTNATHAARCAYYTNYTNAGYGGNCCNYTNGCNGGNTCNACNCCNATHATH TCNACNCCNTCNGTNACNCCNGTN------------------------------------ ---CCNTCNAARAARTCNACNAARAARATHAARTTYGAYGAY------GGNTCNTCNACN CCNAARTCNAARCCNAARGARAARAARATGAARATHGARATHATGTCNCCNTCNGARYTN GGNCCNCCNGTNTCNAARCCNGCNCCNACNGARCCNAARGCNGCNGGNYTNAARATGAAR ATHGTNGGNGGNTCNAAYCCNATGATGGCNAARATHGCNYTNGTNGARGGNAAYGCNGAY AGYCARACNCCNGCNAARACNAAR---AARGCNGTNAARAARCARAARACNTCNAARGAY TCNAAYGARGARATGAARYTNGCNGTNTCN---------------------------AGY TCNACNGAYGARGARAARAGYGCNAARAARAARAARGCNTCNAARAARAARGARAARYTN ATHCARGAYGCNATHAAYGCNGCNCARCARGTNCCNAGYATHAGYGGNTTYGCNTCNCCN ---CARTCNCCN---------------------------CCNGTNACNCARAARACNAGY AARAARAARGARAARAAYCCNCCNGCNAARAARGARCCNATH---------TCNYTNAGY GAYTCNYTNGTNATGGAYTTYGAYGAYGGNGAYATGGARGARGARGGNGARGARGCNACN YTNGTNATHGCNGARACNGARAARAARAARAARGCNGGNAARAARACNAARAGYCCNAAR GARGCNAARGTNAAR------------------GAYGAYCARGCNAARAARATHCCNAAR MGNGCNCCNACNGCNTAYATGYTNTTYTGYAAYAAYCAYMGNTCNGCNATHGTNGCNGAR AAYCCNGGNATHGARTTYGCNGCNATHAGYMGNAARYTNGGNGARYTNTGGCARACNCAR TCNAGYAARCARAARYTNYTNTGGMGNMGNAARGCNCARMGNMGNATGAAYAARTCNAAY YTNATHTCNACNGGNAARAAY---GGNAARGARTCNCARGGNGGNTCNGGNGCNAAYTTY ATHACNTCNGGNTCNACNGCNCARTCNACNAAYCARAARYTNGCNYTNATGYTNCARAAR AGYMGNCCNGTNGTNGTNGAYGARGGNTCNYTNAGYCCNACNAARACNTTYAGYATHGAR CCNYTNGAYGTNGCNGCNCAYYTNAARYTNYTNGGNGARTCNYTNAGYATHATHGGNATG MGNYTNCARGARCAYAARGGNATGATHGCNGTNCARGGNAGYYTNTCNGTNYTNYTNGAY TCNYTNYTNTGYGCNTGYGGNCCNYTNYTNTGYYTNACNCARCARGTNCCNGGNATGGAY GGNTGYTCNCCNTCNGTNCAYGCNCARACNYTNGAYAGYGTNGCNTAYGTNATGCCNGGN YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARGTNGCNTGYTAYTTYTGGCCNMGNGTNACNAARGCNTCNAAYAARACNAAR ATHTTYATGATHAARGTNAARGAYAARAAYAAYGAYGARCAYGTNTAYGCNTTYGARYTN GCNTCNAARTCNGCNTGYAARCAYYTNTGGAARTGYTGYGTNGARCAYCAYGCNTTYTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNGTNTAYATHMGNGAR GARMGNMGNAARTCN---AARGAYAAYTCNGCNGARACNTGYTGYATHATHGCNYTNTGY AGYGCNYTNYTNTGYTGYTGYYTNATG--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ GAYTTYGGNMGNYTNCAYMGNCARAAYTCNTTYGAYTTYCAYGARGGNAARMGNTAYCCN CCNGGN---CCNAARTAYMGNCAYCAYTCNGTNGAYGAYGAYGGNGCNTAYGGNTCNTAY GGNTAYGGNTAYTAY---TCNAAYTAYAAYTAYGAYAARTAYGGNATGCAYTTYAGYTCN CARCCNTCNYTNGCNMGNAGYGGNAGYMGNGAYGGNAARTTYGCNCAYGGNMGNYTNAAY CARGGNAAY--------------------------------------------------- ---CAYYTNYTNAAYGGNCCNCAYGAYYTNTTYGARCCNMGNGAYCARMGNAAYGGNGAR GGNAARGAYAARGAYAARCAYTCNGGNAARGGNMGNCCNTTYGCNGAYGAYTTYCCNTCN YTNAAYGGNTCNGGNGARAAYGTNTCNGAYTCNAARACNAARCCNGCNTCNGGNGTNTGG GARAAYCCNCCNAAR---TCNACNAAYAARAAYGAYGARTCNTCNGAYTCNTCNAARGTN AAYTCNCCNGGNATHTAYAARGCNYTNGTNCCNAGYAARAGYGTNCARAAYAARAARTCN GCNAARGARACNTCNMGNATGAAYGGNAAYGTNMGNGARATHTCNCCNYTNAGYCCNTCN AAYAARCCNGGN---AARGARGGNTCNMGNTAYAGYCCNACNCCNGAYYTNGCNATHGTN ACNCARCCNAARAARYTNGGNGAYAARAARAGYGAYTTYYTNMGNGCNATHMGNAAYGAR AAYTCNATHMGNAAYGGNGAR---GTNTCNCAYCARAAYCARAAYACNATHAARAARCAR GARAARCARGTNCAYGGNGAYGAYAAR---------AAYGAYAAYTCNATHTGYAGYMGN GTNAAYGGNGAYMGNGAR------------------------GTNGAYTCNAAYGARAAY YTNYTNAGYYTNAARAARGAR---TGYYTNAAYGGNGAYAAYGGNGAYGCNYTNATHAAY CAYGTNGAYCAYATHACNYTNTCNGGNGARGARGARGARMGNMGNYTNYTNYTNTCNATG GGNTGGGARGARGARGAYAAYACNGARTAYGTNATHACNGARGAYGARATHMGNGARTTY CARAAYYTNYTNCARAAYCAYTGYCAYGGNCARAARAAYGGNYTNAARTCNTCNYTNMGN AGYGCNYTNGAYMGNAARTTYGGNGCNGARTCNGCN------YTNAAYGGNATHCCNTCN GAYGARGARAARACNGAYAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYGGNMGNTAYCCNMGNGARTTYAAYCCNAARGTNCAYGGN CCNTAYYTNCCNGGNMGNTTYTAYGGNAARCCNGAYACNCCNTTYGGNCARGTNAARYTN GGNGARGTNGGNGCNTGGTTYGGNMGNMGNAAYAARAGYCCNACNTCNATGTGGGARGCN GTNCAYMGNGGNTAYTGGMGNTGGGCNACNAARAAYYTNCAYGTNMGNCAYAGYGGNTTY GTNCCNATHGGNCARGCNGCNATGGTNATGTCNATHTTYTTYTTYGGNYTNYTNTAYAAR GARMGNAGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TCNGARYTNGARGGNYTNGAYMGNGCNTAYTCNGARAGYAARGAR GARYTNAGYAARTGYGARGAYATGATHCAYCARYTNACNACNGARYTNGAYTCNGCNCAR AARGARATHGGNTCNGCNCAYAARMGNGTNAARGAYYTNGARGAYAGYAGYMGNGAYYTN MGNGARCARYTNCARAAYGCNCARCAYCARGCNYTNCARAAYGAYGARMGNGCNCAYAAY YTNGARAAYAARTTYYTNTCNTAYCARGGNGARCAYAGYCAYTCNGAYMGNGARTTYYTN CARMGNGARGARCARATHAAYTCNYTNGARTAYCARYTNGARGARGCNMGNGGNGAYATH CARAGYMGNGARTCNACNATHGARCARYTNAARAAYGAYYTNTCNATHTCNCARTCNGAY YTNCARCARACNGTNGARGAYAARAGYACNGCNATGAARGARATHGAYMGNYTNGARCAR CAYAGYGARCARYTNCARYTNAAYYTNACNTCNTCNCAYCARMGNCAYAARAGYGARACN TGYMGNTTYGARGARCARATHACNTCNYTNGARMGNCARGTNTCNGARGARCARYTNGCN CAYCAYGCNTCNGARTGYGARGTNAAYAAYAARGARGARCARATGAARMGNAAYGARGCN GARATHGCNACNTGYMGNGAYGAYATHMGNTCNAARGTNGARGARATHGARMGNYTNGAR MGNTCNTTYCAYGAYACNAARCAYGARYTNAAYCARGCNATHGGNCARTGYAARCAYYTN GARGCNTCNATHACNGAYATGAARGCNGARGGNGARATHATGMGNAARGAYATGGCNGAY TCNMGNAAYCARTAYAARGAYTGYGCNCARGARYTNGCNCAYCAYGARGARAARYTNAAY YTNATGGARCAYAGYYTNCARTCNACNCARGAYCARYTNAGYCARMGNGTNACNGARATH GTNMGNCAYGARCARAAYACNMGNAARYTNCARGCNGARYTNAARGCNACNAARGAYMGN GCNCARGCNTAYGARGARGARYTNGAYGARCARAARACNTCNATHGAYAARYTNMGNAAR GAYYTNGTNATGTCNAARGARGARTTYCAYTCNTCNGTNCARGARGGNATHGCNTAYAAR CARCARTCNCAYAARAAYGARYTNGARYTNTCNGGNAGYMGNGARCARGARAARATGYTN TCNGAYCARGTNGARCARCARGARCARATHYTNAAYCARYTNCARACNGARYTNMGNGCN GARMGNGARMGNCAYGGNGAYACNGTNAARCARYTNTCNGCNTCNAARAARACNGGNYTN GAYYTNCARGCNGAYTTYGARGCNGTNCARAARCARGCNMGNGARYTNCARGAYMGNGTN AARGCNMGNGARGARCARATGACNMGNYTNMGNYTNGARATHGAYAAYATHCAYCARAAR AAYMGNGARGCNAAYGARTCNYTNGCNGGNAARGAYGGNCARYTNMGNYTNGCNGARATG AAYYTNCARACNGCNGARAARCARGCNMGNCAYCAYGARCARGARATHGCNMGNTAYGAR GAYACNYTNGCNCARYTNCARACNGAYCARGARAARYTNCARGARCARTAYMGNCARACN GCNTCNAAYYTNATGGARGCNGAYAGYAARGTNCAYGARYTNAARGTNCARYTNACNACN GTNCARGGNCAYCAYAARGARGCNATGGARCARYTNACNGARAARGCNMGNCAYTTYGCN GCNATHAARACNGARGCNGCNAARATGGGNCARCARAAYAAYTCNATGAARGARGARATH ATGYTNTAYGAYGARAARGTNMGNMGNYTNCARCARGARYTNMGNAARTCNCARGARATH AAYAARGCNACNGARGARGARYTNCARCAYTTYGARGARMGNTAYACNAGYYTNCARGTN GAYYTNGTNACNAGYCARGARAARCARAARCAYTCNYTNCARGARYTNTCNTCNMGNGAR GARGARAAYGTNGTNACNAARGTNGARYTNAGYTCNATHCARGARMGNTAYAARTCNYTN AAYGAYGARATHACNAARYTNACNGGNGARYTNGARYTNACNAARCARAAYTAYMGNAGY GCNACNGARGARATHTCNGGNYTNMGNGTNGCNYTNGARGARTCNMGNGCNAAYGGNGAY MGNYTNCAYMGNGARAGYGARYTNGTNGTNCAYAAYGTNAAYACNTGGGTNCARGARCAR AARATGGCNAAYGARAARYTNGGNAAYAARATHMGNGARCARAGYAARTCNATHATGGCN YTNACNTCNGARAARGARGGNYTNYTNGAYCARGTNACNAARYTNCARAARCAYTAYAGY AARACNMGNAAYGARYTNGARGAYAARACNGTNGARTCNGAYAARYTNMGNGCNYTNCAR TCNCAYTCNGCNCARCARCARATHATHYTNAAYCARYTNAARGGNMGNYTNGARGARCAY GARYTNGAYAARGAYCARGAYATHAARTCNAARYTNGCNACNATHGARGAYYTNCAYTAY MGNYTNAARTCNAAYATHGAYAGYATHCAYCARYTNAAYCARCARYTNAGYACNYTNCAR AARGAYAAYATHMGNATGMGNAGYGARYTNGAYMGNGARATHGCNACNMGNCARACNATG GARATGCARATG------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARMGNACNMGNGGNCARMGNGAYMGNYTNMGNCARATGMGNCAY GAYAAYMGNMGNGTNACNGTNCARGGNYTNGCN---------AAYCAYCCNTCNTCNTCN GGNYTNTAYGAYGAYAGYYTNTCNGAYTAYGCNGAYCCNCCNMGNCCNGARGTNTCNGAR AAYYTNGTNTCNGCNTAYAARAAYATGACNAARGARGARYTNYTNMGNGTNGTNATHCAR ACNAARGCNCARATGATHMGNAARGAYCARTAYATHAAR--------------------- ------------------------------------------------GTNYTNATGATH AGYAARYTNTGYATHCARYTNAARYTNAARYTNACNACNGTNTTYMGNAARGTNGARGAR AAYAGYACNYTNGTNAGYTGYCAYGTNTTYGTNGCNGARMGNYTNATHGCNATHGCNACN MGNACNAGYMGNMGNGARGCNCARAAYGARGCNTTYAARATHGCNMGNMGNACNYTNGCN GGNCARTCNGGNAARGARGTNYTNGAYACNTGYGCNGCNATGATGCCNCAYGAYYTNAAR GGNAGYGAYATHYTNGAYATHGTNTAYAARGGNTAYACNAARACNACNGARTCNAAYMGN TGYMGNYTNCAYMGNGCNMGNAGYGTNGGNYTNGTNYTNACNATGAARYTNGAYYTNYTN CARTAYGTNGARATHYTNAARGAYTCNCCNAAYCARACNCARGGNMGNTAYMGNYTNYTN CCNGAYTGYGARMGNCCNTCNTAYAAYGAYGTNGCNGGNGARATHGCNGTNAAYGAYTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGAYTCNTCNGGNTCNAARAARCCNAARGGNATHYTNAARAGYTCNAAYAGYATHGAY CAYAGYAARAARGARYTNGARTGGGAYGARATGAAYATHYTNGCNACNCAYCAYCCNCCN GAYAARGAYTAYGGNTTYATGAARGTNGAYGARCCNCCNACNCCNTAYAAYAAYGCNGCN ATHTCNGAYGGNGARGAYGAYGGNGCNTCNATGAARAARAARGGNAGYTTYGAYGGNTCN ACNAGYYTNGAYCCNTCNGAYYTNGCNTCNMGNYTNACNGCNAARGGNGGNGARAARGGN CARAARTAYGTNGAYGAYGAYGAYGAYGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GTNGAYATGMGNATHACNCAYTTYGAYATHGGNGAY ACNATHGCNCARMGNMGNMGNMGNGCNGGNATHTTYAARACNAGY---ACNGGNCCNCAR GARMGNCAYAAYACNATHAGYAAYAGYATG---TCNAGYAGYTAYCARGTNACNMGNATG MGNAAYYTNTCNGGNGGNAGYAGYAGYAGYGCNGCNAGYGGNAGYAGYATHTCNTCN--- ------YTNGAYAAYCARTAYTCN------TCNCARGARAGYCCNTAYTTYTCNATGGAY ACNAGYCCNTTYGCN---AAYTCNTCNCCNYTNCCNGARTAYAAYGAYGAYTCNGTNTCN TCNTCNCAYMGNAARYTNGAYMGNAGYYTNAGYGAYAGYGAYAGYGARAAR--------- ---------GGNTCNCAYMGNTCNGTNAAYTCNAGYMGNTAYAARACNGARYTNTGYMGN CCNTTYGARGARAGYGGNTCNTGYAARTAYGGNGAYAARTGYCARTTYGCNCAYGGNGCN CAYGARYTNMGNAAYYTNGCNMGNCAYCCNAARTAYAARACNGARCCNTGYMGNACNTTY CAYACNATHGGNTTYTGYCCNTAYGGNCCNMGNTGYCAYTTYYTNCAYGARAGYGAY--- ------AAYGGNACNGGNACNCCNAAR--------------------------------- ---GCNTCNAAYAGYGGNAGYAGYAGYCCNTCNYTNAGYCCNACNGGNAAYGARAAYCAY TTYTCN------------TAYTCNGAYTCNTCNCAYACNYTNATHAAYAAR--------- ---------------TCNYTNTCNGTNAAYATHAAYTGYGGNAAYGAYATGAAYTCNYTN GAR------------CAR---CAR---TTYTCNTCNGCNYTNAAYYTNAAYMGNGCNGAY TCNTCNMGNAAYGCNTTYAAYAAY------------------------------------ ------AAYACNTCNGAYGARTTYGAYATHTTYAGYTCNATHTCNGTNTTYAAYGCNGAY GARGTNGTNAAYGAYAAYTCNCCNAARTCNACNTCNTAYTCN------------TCNTCN CARTCNACNCARYTNGAYAAYTAY---TCNTAYCARGGNTTYGGNAGYATHCCNCAYTTY TGGTCNAAYCAYCCNTCNCARGCNYTNGCNCCNGCNGAYCCNTTYCAYCAYTCNCCNACN GGNTCNACNGGNTCN------------------------TCNYTNTCNGGNTCNGARTCN GGNYTNAGYGAYTAYAGYAGYGGNTCNAGYAGYAGYMGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGYTN MGNAAYATHTCNTCNGCNGCNTGYGCNYTNGCNGTNGGNGTNAARGAYTTYGCNGAYGGN TCNAAYGAYTCNATGMGNGTNACNGCNAAYMGNYTNTGYYTNGAYAARTGYATHCCNAAR GTNCAYGCNAAYAGYGAYAAYGTNTAYGTNGGNGAYMGNATHAARAARGCNGTNGGNTTY CCNCARYTNACNGCNTGYTGYAARCCNYTNMGNTAYMGNGAYTTYATHATHTCNTAYGAY ACNAARAAYMGNATHCCNAAYTGGGTNTAYGARCAYYTNTAYTTYAGYAARYTNTTYAAR GAYGAYCCNTGYGAYAARMGNCCNYTNTGYTCNGARATHAAY---GCNGARAARCCNAAR TTYCAYCCNGAYTGYMGNATHCAYGGNTAYCAYMGNTCNGAYGTNAARGAYTAYTGYGAY TCNGAYTAYGARYTNGGNYTNATGGCNGAYCCNGCNAAYTAYCCNTAYGAYTGYGARGCN GCNAGYGARACNCARGTNATGACNAAYGTNGTNCCNATHGTNCCNGGNTTYAGYTGYGGN CCNTGGTTYGAYYTNCARTGYTAYATHMGNGAYACNYTNGTNAARGARCAYAARAGYGTN TAYGTNTGYTCNGGNCCNYTNTTYYTNCCNGAYCARCARCARTCNACNAARTCNATGAAR TTYGAYGTNYTNGGNGARGGNGARGTNTCNGTNCCNACNCAYTTYTTYAARGTNATHATH ATHGARACNYTNGAYGGNAAYYTNGARYTNGARTCNTAYATGATGCCNAAY--------- AARGARYTNGAYGAYTCNGAYYTNGAYAARTAYYTNACNCCNYTNTGYAARATHGARCAY TAYTCNGGNYTNATHTTYTTYCCNGARAARAARGTNTGYTTYACNAGYAAYAAYAARMGN MGNGGNGCNATGYTNCAYGCNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNGCNCARGARGGNATHGARGARAAYAARYTNCCNCAR ATHTTYGCNGAYGGNATHCAYATHGGNGGNGCNGGNGARATHGARMGNYTNAAYGARGCN GGNGARYTNMGNGCNYTNYTNGARGGNTAYCARAARATHAAYGTNMGNTTYGCNTGYGAR AARTGYGGNGGNTAYMGNTTYACNCCNTGYGARTTYTGYCAYGGNAGYAARMGNTCNYTN ATHMGNCAYCAYGTNATGGARGARTTYGTNGCNYTNMGNTGYATGCAYTGYGAYGARAAY GGNYTNMGN------------------------------YTNGGNTCNTAYTGYAARAAY ATHYTNYTNAAYATGACNGTNCAYGTNGGNYTNGARGTNAGYYTNTCNAAYTGYAARYTN GCNAARGTNTAYGGNATHACNAAYATHTTYGTNTCNAAYATHAARTCNAARAAYAAYGAR YTNTCNGGNCAYGTNATHGARTCNAGYAARATHCARATHTCNTCNGTNCAYAGYGARYTN TTYCAYAAYYTNGTNAARAAYYTNCCNCAR------------YTNGGNGGNYTNACNACN GARYTNGARAARGTNMGNAARYTNTTYMGNYTNAAYAARYTNAAR---ACNAARYTNTAY MGNCCNMGNGGNATHYTNYTNCAYGGNCCNCCNGGNTGYGGNAARACNTCNTTYACNAAR GTNYTNGCNAARGARTGYGGNGCNATHYTNTAYTCNGTNGAYAARTTYGAYYTNYTNACN TCNGAYTTYGGNAGYGGNGTNGCNACNGTNAARGARATHTTYCARAARGCNGTNGAYYTN YTNGARGARGGNCCNGTNATHATGTTYYTNGAYGARATHGAYATGYTNTGYCCNMGNTCN GARACNGCNAGYYTNGGNAAYAARCARYTNACNAGYGCNATHACNACNGARATGGAYAAR YTNCAYTTYAGYAAYATHTCNAGYYTNYTNATHGTNGGNGCNACNAAYTCNGTNTCNAGY ATHGAYCARAGYYTNMGNMGNCCNGGNMGNTTYGAYCARGARATHYTNATHAAYATHCCN TCNGARGAYCARMGNGTNTCNATHYTNAARACNYTNACNACNMGNYTNCARYTNTCNTCN GAYGTNTCNTGYAARACNYTNGCNCARATGACNCCNGGNTTYGTNGGNGCNGAYYTNAAR TGYYTNTGYGARGARGCNGTNAAYCAYGCNGARGARAARGAYYTNACN------------ ---GARATHTCNMGNGARGAYTTYAAYGTNGCNYTNCAYAARACNGTNCCNTCNYTNAAR AARGGNTCNGARTGYGTNGTNGAYYTNAARCCNGTNAARTGGGARGAYATHGGNAGYYTN GAYGARATHAARATGGARATGAARCARTCNYTNGARTGGCCNYTNAARTAYCCNGAYATH YTNMGNAARCAYGAYATHCCNCCNACNAARGGNATHYTNYTNTAYGGNCCNCCNGGNTGY TGYAARACNACNYTNGTNMGNGCNGCNGCNACNTCNTGYAAYGTNTCNTTYYTNTCNYTN AGYGGNGCNCARGTNTAYTCNGCNTAYGTNGGNGARTCNGARMGNATHATHTCNCARGCN TTYCARAARGCNMGNGCNYTNGCNCCNTCNATHYTNTTYTTYGAYGARATHGARTCNYTN GTNGGNAARMGNAGYATHCARACNGGNAAYAGYMGNGTNCARGARMGNATHYTNTCNACN ATGYTNAAYGARATGGAYGGNATHGGNAAYAARYTNGAYYTNAARACNTCNGCNCCNMGN GAYCARGTNCARTCNCARACNACNYTNCARTGYCCNATHGGNGARGGNYTN--------- ------------------------GAYATHGTNACNGARGARAAYCAYAAYAGYAAYCCN AAYMGNYTNAGYGTNATHGTNGTNGGNGCNACNAAYMGNCCNGAYATGYTNGAYGCNGCN ATHYTNMGNCCNGGNMGNYTNGAYAARCAYATHTAYGTNCCNCCNCCNGAYCARGARGTN MGNAARTCNATHYTNGARATHTAYACNTCNAARATGGCNTGYCAYGGNATHGAYATHGAY YTNYTNGCNAAYAAYACNGAYTAYTAYAGYGGNGCNGAYYTNAARAAYYTNTGYAARGAR GCNGGNYTNCARGCNGTNMGNGARCARATGTCNAARACNGGNAGYGARTAYAAYYTNTCN GTNAAYAAYYTNCAYTTYAARGCNGCNYTNGARGCNATHAARCCNTCNYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNACNAARAARGTNATH TGYGAYCARYTNGTNGCNGGNCCNTTYTTYTGYACNTCNTTYYTNGTNGGNTCNACNYTN YTNGARGGNGGNGGNGTNAARGGNGCNAARACNGARYTNAARGARAARTTYYTNACNATH TAYATGGTNGAYTGGTGYTTYTGGCCNGCNGCNCARATHATHAAYTTYAGYTTYATHCCN AGYMGNTTYMGNGTNYTNTAYGTNAGYTTYGCNACNYTNGTNTGGAAYTCNTTYYTNTCN TAYATHAARCAY------GTNYTNMGNGGNYTNTGGAAYGARYTNYTNCCNTAYTTYAAR ACNAARATHATGTTYAARGCNMGNATGMGNGAYGTNTAYYTNAAYYTNYTNGARGAYCCN TGYTCNACNATGTTYTAYYTNYTNYTNYTNACNTTYGGNTTYATHCCNTTYYTNACNTTY ATHTTYTTYATHATHGGNTCNTTYYTNTTYGGNATHGTNTGYTTYTTYGTNTCNCARGCN ATHGTNYTNACNGCNTCNATGTTYGTNTTYGGNGGNTTYATGATHTTYATHGCNTTYATG TGYTGYTGGYTNGCNGGNATHTTYGGNACNTTYATHCAYATHTCNYTNTAYTGG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARGARTCNTAYGARCARYTNGARAARGAYGTNGCN---------------TAYTGGAAR CARCARAGYTCNAAYYTNTGYYTNCCNGARGCNTCNTCNCARYTNAAYMGNGARGTNMGN YTNGCNGCNTTYGARAARAAYTCNTCNGAYGTNGARAARYTNATHGAYGARGCNAARACN GARAARYTNCARCAYATGGARGARYTNCAYGARAARAAYAARAARYTNGCNGARYTNGAR GCNAARGTNAARCARYTNCARACNCARYTNGTNGARAARGAYGCNYTNGTNAARGTNTTY CARMGNTCNCCNYTNTCNYTNCCNMGNAGYTCNAGYYTNCAYGCNYTNTGYCAYGCNCCN TTYCAYTCNCCNMGNCCNTCNYTNATHGCNTCNCARGCNYTNGAYGGNGAYACNCCNTGY CCNTCNTCNTCNGTNGTNGGNACNCAYMGNGARTTYTCNTCNATHMGNCAYATGAARACN GGNAGYACNAGYGCNATHGAYATGGGNMGNAARATGTCNYTNGARGAYGAYYTNYTNACN AARGTNCAYAAYYTNAAYGTNGARACNAARGAYGAYACNGCNGARGARATHCARYTNTGG CAYGTNAGYTGYAARTCNACNGARGGNTCNATGAARACNGARGAYGAYGAYGAYGAYGAR GAYGARAGYAAYCAYGGNAAYATGGARGAYGAYACNTCNGARGCNGGNTAYGAYCCNGAY ATGGAYCCNAAYAAYGTNCCNGARYTNACNMGNMGNGCNGTNGAYGARGCNTAYGAYCCN GAYATGGAYCCNAAYAAYGTNGTNYTNMGNAARAARCCNAGYAAYCCNGARTCNGARGAY TAYGAYCCNGAYATGGAYCCNAAYAAYGTNGTNYTNMGNMGNAARCCNMGNCCNGTNAAY ACNACNMGNAGYCAYGCNATGGTNATGTCNACNGAYGARGAYGAYGAYGARGARMGNCCN TAYAGYYTNTCNGCNTAYMGNAARAGYCARAAYGTNAAYYTNCAYACNYTNGAYCCNATH GTNMGNAARAARGARTAYAGYAGYMGNMGNGTNGTNGARGARGAYGTNTTYATGCCNACN TCNCCNMGNCARCARAARGAYAAYCCNYTNGCNATHCARGARMGNATHAARGARATGCAR GARYTNGTNCARCARGARCARAAYGTNATHATGCARACNAGYAAYGCNYTNAAYAARTGY TGYGTNGGNAAYGCNTAYTTYGCNGGNTCNGCNGARCARGTNGARTGYAAYMGNYTNYTN YTNATHTCNTGYCARAARMGNCARGCNTAYATHAARGARATHCARMGNYTNAARCARACN GGNYTNYTNGAYCCNTGYGGNCCNGGNCCNCARGGNTCNYTNACNATHAGYGAYATHMGN YTNCCNYTNAARAARGARTTYGTNAARAARATHGGNACNTCNTCNGAYAAYACNACNCAY TAYTTYATHYTNYTNATHMGNAAYCAYAGYCARGTNATHTGYACNCAYATGYTNTCNACN CAYGAYTCNATGATGMGNGGNAGYYTNGAYTTYCCNAAYYTNATHAARATHAAYGGNATH ACNGGNGAYTTYAARYTNGCNGTNGAYATHTAYGGNATGAGYGTNCARMGNGARYTNTCN AARGAYAARAARMGNAARACNCCNAARAARGGNAARGGNTAYGCNACNGCNYTNGARAGY CCNGGNGGNCCNACNGCNGTNMGNACNACNAGYTTYAGYCAYGTNGAYMGNGTNGARYTN ACNATGAARAGYYTNGAYAARACNTCNTTYCAYYTNGAYMGNYTNCCNCAYYTNTCNCCN YTNTAYGGNCARATHTTYATGMGNTTYAARTGYYTNATGGARTCNCAYGTNGARGARMGN GGNTTYYTNACNATGTTYGARGAYGTNAGYGGNTTYGGNGCNTGGCAYMGNMGNTGGTGY GTNYTNTCNAGYAAYAARYTNTGYGTNTGGAARTAYCCNGAYGAYGARACNMGNAARGAY CCNATGACNATHATHGAYYTNAARMGNTGYATHACNGARAARGTNGGNYTNGTNCCNMGN GAYATHTGYGCNMGNCCNAAYACNTTYGARATGGTNACNGTNMGNCARCCNYTNAARGGN GARCAYGAYACNYTNATHTCNAARACNMGNAGYACNGTNACNTCNGTNMGNCAYCARATG TCNGCNGAYACNAARGARGARMGNATHATGTGGTGYAAYAARATHAAYAARACNYTNGCN AAYTAYMGNACNTGGAAYCCNGAYGCNYTNMGNCCNACNAARGAYTTYGARTCNTCNAAR ATHGGNACNCARGARTAYTGGGAYAAYACNTAYGARAARGARYTNGARAAYTTYTCNCAR TTYGGNGAYGTNGGNGARATHTGGTTYGGNGARGAYGCNCARCARMGNATGGTNMGNTGG GTNGCNGARAARCARGARGTNCCNACNTCNGCNAARATHYTNGAYYTNGGNTGYGGNAAY GGNATGYTNYTNATGGCNYTNMGNGARGARGGNTAYGARAAYYTNACNGGNATHGAYTAY TCNGAYAAYTCNATHAARYTNGCNAAYCARATHGCNGARACNGARGGNGCNAARGAYATH GTNTTYGARGTNTGYAAYATHYTNTCNCCNGAR------GARGCNGCNAARCAYAARAAY AARTTYGAYYTNTGYYTNGAYAARGGNACNTAYGAYGCNATHAGYYTNAARAAYACNGAR GAYCCNACNGAYMGNAARYTNTAYATHGAYCAYGTNTAYTCNATGYTNAAYGAYAARGGN YTNYTNGTNATHACNTCNTGYAAYTGGACNAARTCNGARYTNYTNCARCAYTTYGGNAAR GTNTTYAAYYTNACNGAYGARGTNCCNTCNCCNAARTTYACNTTYGGNGGNCARACNGGN CARACNGTNACNACNGTNATHTTYACNMGNMGN------ATHYTNGTNTTYCCNGARGAY GGNATHTAYGGNATGMGNTTYAARGGNMGNGARGCNATHMGNCCNTTYYTNGARGTNATH CCNGAYCCNAARCARACNAARTGGAAYCCNTGYACNAAYCARGARCARMGNAARAAYATH GARGTNCARAARACNYTNAGYTGYATGGCNAARGAYAAYCARATGTAYATHGTNGCNAAY ATGGGNGAYTTYGTNGARTGYGAYMGNAARACNGAYCCNTCNTGYCCNAARGAYGGNCAY TAYCARTAYAAYACNGAYGTNGCNTTYGAYCCNACNGGNCARYTNGTNGCNAARTAYCAY AARACNCAYYTNTTYTTYGARTCNCARTTYGAYACNCCNAARGCNGARGTNGTNTAYTTY GAYACNCCNTTYGGNMGNTTYGGNATGYTNGTNTGYTTYGAYYTNYTNTTYAARGAYCCN GCNGTNACNATGGTNACNGARCAYCARGTNGGNAAYATHYTNTTYCCNACNGCNTGGATG GAYGCNYTNCCNYTNYTNCCNGCNATHGGNTAYCAYTCNTCNTTYGCNMGNGGNYTNGGN GTNAAYYTNYTNAGYGCNAAYGTNCAYATHCCNGCNTAYMGNTTYCARGGNAGYGGNATH TTYACNCCNGARGGNGCNGCNAAYTTYTAYTAYTCNAARAAYATHACNTCNCCNGGNAAR YTNGTNGTNTCNACNATHAAYGTNGTNAARCCNGGNCCN---------------AARGCN AARCAYGGNAGY------------GAYATHYTNCCNACNCCNACNAAYATHGTNCARGAY GTNAAYAARCARTTYCARTCNGAYYTNTTYMGNGAYGAY--------------------- ------------------------------------------------------------ ---------------TAYACNTTYCARYTNYTNACNCARTCNTCNGGNAARATHAAYGTN TGYCARAARAAYGTNTGYTGYTCNYTNAAYTAYACNATGAGYCARCARACNACNYTNACN GARYTNTTYGCNTTYGGNGCNTTYGAYGGNYTNCAYACNCAYGAYGGNCARTAYTAYTTY CARACNTGYGCNYTNGTNAARTGYGGN---AAYAAYGTNAAYAARTCNAGYTGYGGNGAY TTYACNTTYGAYTCNAARACNACNTTYTCNTCNYTNTCNATHAARGGNTAYYTNCARACN AARTTYGTNTAYCCNCARGTNATHGTNGCNGARAAYGARCARYTNATGYTNACNGAYGAR TCNGCNTGGACNTTYAGYAAY---GCNCAYYTNGAYGTNGGNCCNGCNGCNAAYAARCCN YTNATHTCNGCNYTNYTNYTNGGNMGNGAYTAYGCNMGNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CAYCCNGCNATHTGYACNGGNYTNAAYACNGCNAAYTCN ACNYTNATGGCNACNGCNAAY---ATGAAYATHAARGTNTAYGARCCNCCNCCNAGYCCN CCNGTNATGACNTTYAAYGGNGCN------ACNGTNACNAAYGGNAGYGTNATHGARTTY ACNAAYGGNAAYAARGCNACNATHTCNTGYCARATHGAYGGNGGNTAYCCNACNGCNTCN AAYATHACNYTNTCNTGYCCNGAYGGNAAYTCNAARACNCARAAYGGNGTNTCNGTNTCN ATG---GARTTYGAYGTNACNMGNACNCAYCAYCARCARACNTGYACNTGYTCNTTYAAY CAYATHTCNAAYTGYCARAAYYTNACNACNACNTTYACNTTYGAYGTNYTNGARCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------YTNAARMGNAAR--- CARCCNCCNGTNCARGARGTNGGNGGNCCNYTNMGNYTNGGNAARGGNGGNGGNCCNGGN YTNGCNGTN---------GGNGTNTCNCCNCCNAARMGNGTNAAR------GGNATGYTN ------CCNGGNGAYATHGARATHTCNGARYTNGAYGAYYTNTCNAARTAYGTNAGYCCN ATHCARGGNTTYMGNGTNATHGTNACNAAYYTNTTYACNGGNGTNACNCARGARGAYATH ATHGARYTNTTYGGNGTNGTNGGNCCNYTNAARAARGCNMGNYTNYTNAARGCNGGNTCN GCNGARGTNGTNTAYACNACNMGNGARGAYGCNYTNAARGCNGTNCARAARTAYCAYGGN MGNGARYTNGAYGGNCARCCNATGTAYGTNAARATGACNACNCCNYTNGCNGCNGTNGTN AARTTYCCNGTNGGNAAR---GAYCCNGAYATHACNGGNGARGCNYTNMGNYTNTAYAAR AARCCNAGYAGYYTNGGNGCNYTNCCNMGNGCNCCNATHGARGTNCCNACNGTNCARMGN GCNYTNTTYAARGTNGGNCCNCCNGCNCCNAAYAARTCNGTNAARTTYACNGTNAARATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GGNGTNTGGGAYATHTTYATHGAYAARATHGTNGARATHCAYAAYCAYTAYGAY------ ACNGAYTCNAARGAYGTNYTNACNCARTAYGCNACNYTNAAYCCNGGNAAYCCNAAYGCN CAYMGNTAYYTNTAYCARTTYCAYCARGARTAYGAYCAYGAYAAYCARCARGARGTNGAR AARYTNAARAAYYTNGTNAARYTNGAYCCNAGYAAYCCNYTNGTNATHGARYTNTGYTCN YTNYTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TAYTCNATHGTNGTNCCNTAYYTNGCNYTNYTNCCNGTNATGGAYTGY--------- ---AARAARACNGAYAARTGYAARACNTGYAARGARATHGTNGAYAAYTTYAAYAARGGN YTNGARGCNACNGCNAARTCNAAYTTYGGNGGNGGNAAYACNAAYTGGGARGARAARTCN YTNGGNTCNTAYGCNTTYAGYGARGTNMGNYTNGTNGARATHATGGARAARYTNTGY--- ---ACNTCNACNGARTGYCAYACNATGYTNGARAARCAYGARGAYGARGTNGARAGYTTY TGGTTYAARGARTTYGCNAAR---AAYAAYAARGAYATHCAYACNTAYYTNTGYATHAAY CAYATHAARGTNTGYTGYCCNAAYAAYACNTAYGGNAARGAYTGYGARCCNTGYCCNGGN GGNGTNGARAARCCNTGYAGYGGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGGNGGNACN GARAGYAARMGNMGNGTNGTNGTNGARGAYGTNAAYGGNGARGGNGTNGTNCARGTNACN GARGCNGTNGTNMGNMGNATGAARGGNYTNCCNGARGCNCCNCCNTCNAARCCNAARGAR ACNYTNGARGAYTCNAARMGNGARTAYGCNCCNGCNGARCAYMGNCARGCNAARGAYGAR GAYMGNTAYAARGARATGACNAARGARATHGARGARTTYTAYTCNGARAARYTNGARGAY YTNGARAARMGNAGYAARAAYYTNCARGAYACNTCNAAYGARCARTTYTCNAARGCNGTN AARGARGTNGARCARAARTTYYTNAARTAYGCNACNTCNCCNGTNTGYCARGAYYTNCAR ACNAARGTNYTNCARTGYTAYCARAARAAYCCNGAYTCNATHYTNGAYTGYTCNTCNGTN GTNAAYGCNTTYACNACNTGYGTNGAYMGNGCNMGNATGACNGTNTCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNMGNGCNCARGARGCNGARCARGTNGCNGAYGARTGYGTNCARGTN YTNGAYGAYTCNACNCCNTCNATHGCNYTNGCNAARATHTAYAGYGAYYTNTCNGTNGCN TAYACNCARATHTTYCARTAYGAYAARGCNYTNCAYTGYAGYGARAARGCNYTNCCNYTN GTNGARGARCCNAGYTGYGAYGCNYTNTTYGCNGCNATHATGTAYCARAAYYTNGGNGCN ATHTAYAAYTAYATGGGNAARTAYGAYAAYGCNGTNACNTTYCAYGARAARGCNTGYAAR ACNTTYGGNCARYTNGGNATGMGNGTNAARCARGGNCAYTGYTTYACNAAYATGGGNTAY GCNTAYAGYCARYTNAARGARATGGAYAARGCNGGNGARTGYTTYYTNCAYGGNYTNCAR GCNGCNMGNGAYTGYGGNGAYYTNAARACNGARTGGCARAAYYTNGARTCNYTNGCNAGY GTNGCNTAYCAYAAYAARACNCCNAARAARGCNGARCARTAYTAYCARCARGCNATHACN GTNYTNTCNAARGCNCCNGAYACNGCNAAYCAYGCNGAYCAYGARMGNYTNATHAAYAAR YTNAARAAYGTNATHCARGCNCARACNCCNATHGCNGCNTCNAARGARMGNGTNAAYAAY YTNGTNMGNMGNGCNAGYCARAARGGNGARAAYATHAAYTAYAARGAYYTNAAR------ ------------AGYATHGCNGAYGARATGGARTCNGGNAAYATHAARGTNGTNMGNMGN GGNAGYCARGTNMGNTAYYTNAARGTNMGNAARTCNGGNACNYTNMGNAARTTYGAYAAR GTNGCNYTNGGNYTNGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGAGYCAYGGNCARAARGARTTYTCNTGYAARGGNATHAARATHGTN GTNGAYTGGTTYMGNAAYMGNGGNCAYAARAAYATHACNGTNTTYGTNCCNCARTGGMGN AARGARGCNTCNMGNCCNGAYGCNCCNATHGCNGAYCARTAYYTNYTNACNGARYTNGAR AAYGAYAARGTNGTNGTNTTYACNCCNTCNMGNMGNGTNGGNGGNACNMGNATHGTNTGY TAYGAYGAYMGNTTYGTNYTNCARYTNGCNGTNGARMGNCAYGGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNGAYGARGAYTAYAARAGYATGGAYAAYTTYYTNGCNGARGGNATGGTNAAR AARYTNCARGAYGGNATHAARTCNCARAARTGYGGNAARTAYACNGTNCAYATHTCNCCN YTNGARATHGCNGAYYTNGCNCAYCCNACNATHCARCARYTNATHCARYTNCAYCCNTCN YTNTCNATGGTNTTYCARCAYCARGCNGTNAARYTNAARAARAARAARGGNTAYGCNGAY GCNGCNTTYMGNACNGTNACNGAYYTNAARGARTTYGTNTAYCARYTNACNCARGTNAAR GTNTGYGARMGNMGNYTNGAYGTNTCNATHTCNGCNGAYCARCCN---------GAYTTY AAYATGTCNTTYACNATHCAYYTNAAYMGNAAYYTNAARYTNATGAAYYTNATHAAYGGN GGNGARGAYCCNYTNATHAAYAARCCNATHCCNATHGAYGARAAYGARCAYAARATHCAR TTYGARAARGTNTCNTCNGTNGCNAAYGCNGCNTTYATGCAYAGYYTNTTYCCNTTYACN AAYAAYGTNCAYATHMGNAARTGYGTNCARGAYACNGGN---AAYTCNATGTTYCAYGGN CCNYTNACNGTNAGYTTYATHAAYGARAARTGGYTNGAYGCNGTNATGACNTGYTGYACN GAYTTYAARGTNAAYGGNTTYCCNYTN--------------------------------- ---------------------------ACNGCNATHGAR--------------------- ------------TGYGARAAYAARGGNGARGARAAYGCNATHACNGAYACNGAYGARGAR GAYTCNYTNTCNMGNYTNACNAAYGAYGTNTAYGCNGARGTNYTNCARTCNATHAGYAAR YTNAARAARYTNGCNCCNAAYAAYCCNAARYTNAARGARATHYTNAARATGCARCARMGN YTNGAYGCNTTYCARAGYTCNYTNAAR------------------------TCNTCNGAY AARTCNTCNYTNGAY---------------GTNTCNATGGARGAYGGNTCNACNYTNAAY ---------------------------AARGARAARACNGARATGGARAARYTNGARGAR ATGTAYGARGARCARGARAARATGGARTAYGTNAARGARCARACNMGNAARMGNCARATH GARAARGARYTNAAYGARAARAARGARYTNGARAARAARMGNAARAGYCARTGGGCNAAR AGYYTNYTNTCNGAYTTYAARGTNGCNGGN---------CCNGTNGGNAAYAARMGNGTN AGYCARGGNGCNGARMGNATHYTNCARCARMGNGARAAYMGNATGAARCARGARGARGAR AARYTNAARAARGARGARGARGARAARMGNMGNCARGGNATGGARGARGARAARATHMGN AARGARGARGARAAYAAYYTNYTNATHMGNMGNATHGARGARGCNMGNCARMGNGAYATG CARMGNGCNGARGARYTNTCNTCNTCNCARTCNATHTGGAARACNAARAGYGAYTCNAGY TCNACNGGNMGNMGNAAYCARGGNMGNMGNCARGTNGARGARAGYGTNGAYAARMGNYTN GARTCNATHGAYTCNTCNTCNGGNGGNTAYGCNTCNCARAGYTCNAGYTAYCAYTCNCCN AAYMGNGARACNGAYCARGAYGCNTAYATHATHCARGARCARGAYTTYGARGTNYTNAAR GARMGNAAYGTNYTNCCNGCNAAYTAYAARGTNATGATGAARGCNGCNATGGAYMGNTAY TGYCCNGCNCCNAAYTGYCCNGCNACNMGNTGYTTYMGNGARTTYTCNGCNYTNATGGAR CAYTGGTCNATHTTYCAYCARCCNAARAGYACNATGMGNTTYTGYCCNAAYTGYACNGCN TAYTTYATGACNGCNAAYGARYTNGARAAYCAYATGAARAARACNTAYMGNYTNTCNGCN ---AARGARGCNTAYCAYAARTGYCARACNGCNMGNGTNAARATHATHACNAAYCCNAGY TTYMGNGAYCCNTCNCCNTTY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYMGN ATHYTNTGGATGTGGCAYGARGCNMGNAARCARGARAARAARATHMGNGGNYTNATGGTN GAYYTNAARMGNMGNGCNGAYMGNMGNMGNGARTTYTAYGARAARATHAARCARGAYCCN ACNCARTTYYTNMGNATGTAYGGNMGNCCNGTNAARATHCAYYTNGAYCCNGCNGTNTCN ATGGCNGCNGARGGNCCNCARAGYATGATGGCNTGGCARGGNGAYAGYTCNAAYATGATH GAYMGNTTYGAYGTNMGNGCNAAYYTNGAYTTYATHACNGARTAYAAYCCNGCNAARTCN AGY------GGNTCNAAYAARGTNGARAARGAYGARMGNYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNYTNTGYGCNGTNYTNAAR YTNGAYGARCAYGARAARGCNMGNAARCARGCNAGYGARTGYYTNGTNTCNGTNAGYGGN YTNGARGCNMGNATHGAYGAYMGNYTNAARGTNTAYAARACNAARTCNGTNACNGAR--- ------AGYATGGAYTAYAGYACNTGGMGNGARGCNGGNATGTCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR ACNGCNATHAAYGCNAGYACNCCNAGYMGNYTNGARGTNAAYAGYCAYGAYMGNATGCAY TAYAAYAAYYTNGARTCNGAYAGYTCNTTYGCNTCNYTNACNGCNCAYCARTCNAARTAY GAYATHAARYTNYTNAARCARAAYCARMGNYTNYTNAAYGARGTNGARMGNYTNGTNGGN CARATHCAYATHGCNAAYCARAARAAYACNYTNYTNGTNAARGAYGCNGARAARGGNAAR MGNGCNGTNGARGTNGARGARMGNTCNYTNAGYYTNTCNGCNGARAAYGARGCNCARGAR AARAARYTNMGNGARGCNGARMGNCAYYTNGARGARGGNCARMGNMGNYTNGCNGARYTN CARAARMGNGTNAAYTTYACNGAYACNGARGTNGTNGAYYTNMGNGCNGARYTNGCNGAR ATHMGNYTNGTNAARMGNGARYTNGARACNCARMGNGAYGAYGCNYTNCAYCAYYTNAAY ACNGCNCARGAYTCNYTNGARGAYTAYCARMGNAARAGYCARGAYAARATHATGCARATG GARGARAARGARGAYCARYTNCARGARGCNYTNAAYYTNACNAGYCARGARMGNGAYGAY YTNYTNGAYCARYTNTCNGGNATGGARATGACNATHGCNTCNCARGARGCNCARATHAGY MGNYTNYTNAAYGAYYTNACNGAYGARGAYAARMGNGCNCARGAYTTYGARAARGCNAAY CAYCARYTNMGNGCNCARYTNGAYCARYTNACNGCNCARATHAGYGARYTNGARCARCAY AARAARGARGCNAARGARYTNAARAARGAYAARGARAAYYTNAARYTNGARYTNAARAGY CAYMGNTCNGTNGCNAARGARTTYAARTCNYTNYTNAGYYTNYTNAARAARTCNGCNGCN AAYAAYAAYGCNGAYGAYAGYGGNAAYTTYAGYTTYAARTCNYTN--------------- ------CCNYTNGARTAYGGNGGNTTYGGNGAYTCNGCNGCNGCNGARYTNAAYTGYAAY AAYAAYGGNYTNGGNTGYTGYGARCCNCCNTGYGARGGNGGNAAYATGATGTGYGARATG MGNAAYYTNGTNACNAAYATGGAYTGYGARATHCARMGNYTNMGNTGYGAYYTNAARCAR MGNGAYGCNGAYGAYMGNACNTAYGCNAAYYTNMGNGAYGARYTNAARGTNYTNATGGAY AARGTNGARAGYGGNATGTGYCAYAAYMGNGAYYTNGARTGYCARGTNGCNCARYTNGAR TGYGAYAARAARACNYTNMGNTGYAARYTNGARGARACNYTNGGNTGYYTNGARGARMGN GAYMGNGCNYTNCARTGYYTNGARACNMGNYTNAAYGARMGNAGYGTNCARATHGTNTGY YTNCARGARGAYATHGAYGARMGNAAYTGYMGNATHAGYGCNYTNGARAAYCARATHCAY GARYTNCAYAARMGNYTNGAYCCNGAYGARGARAARGGNGARTCNCCNGCNYTNAARGAR GCNMGNCAYMGNATHCARGARYTNGARGCNATHYTNGTNTGYAARAAYAARTCNYTNGAY GARATGGGNGCNAARYTNTCNGARACNYTNMGNGARTAYMGNYTNYTNAARAGYGAYTGY GCNAGYGARAARGARTGYYTNGARAAYAAYYTNGCNCARMGNGAYACNGARATHCARAGY YTNAARGAYGAYGTNGARAGYAAYMGNGTNAARCAYYTNGCNYTNAGYAARATGYTNGAR GARCARAARTCNTCNATHMGNGGNAARGARGAYMGNATHAGYTGYYTNCARMGNGARYTN GARGARGTNAARTTYGCNTCNGARAARACNGARAARYTNYTNCARACNCARYTNGAYGAY CARGCNAARMGNYTNAARGCNTGYCARGAYCARTGYGCNGAYYTNGARACNGCNYTNTGY GTNTGYMGNAGYGARGTNTGYAAYCAYYTNAARTCNATGGAYGARATHMGNGCNCARTAY GARGCNGARYTNGARCARMGNGAYTCNTGYATHMGNAARYTNAARGARGAYYTNMGNTGY GCNGTNGARGARYTNAARTGYAARATGGARGAYAAYAAYTCNYTNGARMGNTCNYTNGCN GARGCNMGNAAYAARGTNCAYCARATHTGYTGYCARYTNAARGARGCNGAYACNAAYATH CARTGYYTNAAYATHAARATHTCNGARATGGARAARCARATGYTNAARGARAARGCNAAY TGGATGAARGARTCNGARGARATGGARMGNMGNATGCARCARTGYTGYAAYAAYYTNGGN GTNGCNAAYAGYGARATHGARACNYTNAARCARCAYYTNGCNGARAARAARAGYCARGTN GAYTGYATGCARGCNGARAARACNCAYATGTGYCARGARATHAARAARYTNAAYGAYCAR GTNTGYTGYYTNCARGARCARATHAARAARATGGARATHGAYAAYCARGARYTNTGYAAR CARYTNCARCARAARATGGARTGYATHMGNGAYYTNGARAAYGTNATHMGNGCNAARGAY CAYGARATGAARTGYYTNACNAARTTYGTNCARGARATGGARACNAAYGTNGAYTCNGGN ATHGTNCCNCARYTNGAR------GCNACNATHAARGARYTNACNGAYAARYTNACNAAR TGYCARGARGARTGYAARTGYAARGGNACNATGYTNTGYGARTGYGARGARGCNTTYAAR CARTGYCARATGYTNTGYAARGAYAARGAYAGYGARATHGCNYTNYTNMGNTGYCARATH GARGGNYTNAAYGARAARYTNAAYGAYMGNATHGCNMGNGTNGAYGARYTNGARMGNGGN ATHGARAAYYTNCAYAARGAYGTNGARMGNMGNATGATGMGNGTNGAYGARCARYTNAAR AARTAYGARACNGARYTNGCNGAYMGNATHCARGARATHGCNACNYTNAARGARTGYGTN ACNACNTGYCARYTNAAYYTNTCNGARAARCARGAYGARYTNYTNCARCARGARCARAAR AAYAAYYTNATGGCNTCNGARTTYGARTCNYTNAGYYTNAARYTNAARGAYGCNGARGAY TCNMGNGAYCAYYTNGGNAAYCARYTNGCNGARAARAARGGNGARGTNACNGARYTNACN CARCARYTNMGNYTNAAYMGNGARCARATGCARAARCARCAYGARGAYYTNGTNCARTGY MGNCARGCNYTNTCNTGYGCNCARMGNGAYTCNGAYAARYTNMGNMGNGARYTNGAYGAY GCNATHGCNAGYYTNGARCAYMGNGARTGYGARATHACNMGNYTNAAYGARGARMGNAAR TGYYTNATGGARAARGTNGCNCARATHTCNTGYCARATGGARCARGARACNTCNATGYTN MGNAAYCARYTNGCNGARACNAARTGYMGNYTNGARAARGARYTNGARTGYYTNMGNAAY TAYTCNTGYCARYTNGARGGNAAYAAYGCNGCNYTNAGYAAYAARYTNTCNYTNACNCAR MGNCARATGATGCARATGGARAARTGYTTYCAYCARAARYTNGAYACNYTNAAYMGNAAY TTYGAYGARYTNAAYACNAARYTNAARATGMGNGARGAYGARYTNATGGCNYTNAARGAY TGYATGGAYYTNAARGARTCNGARATHACNMGNYTNAARAARMGNYTNTGYACNTGYAAY GCNAAYTGYCAYAAYAGYGAYTAYAAYGAYTAYCARCARGAYGAYGTNGTNATHGGNTCN GARAGYGCNGAYGGNGAYGARGGNGAYMGNMGNAARYTN---------------TCNAAR GAYGAYTGYAAYYTNAAYGARATHGAYTGGGAYAARGCNGARGAYCAYAGYTGYCARCAR TCNCCNCCNTCNTCNGAYACN---------AGYAGYGCNMGNAAYAGYYTNGGNGTNACN GARGTNCARGARMGNYTNMGNAAYAAYCARATGMGNCARAARGARATHGARMGNCARYTN CARTCNYTNGARGARGGNAGYCARGARGAYYTNGGNTCNGGNGGNTAYGGNGGNGGNTAY GGNGGNAGYAGYTAY------GGNGGNAGYGCNTAYGGNGGNGGNAAYGGNTTYGGNAGY GGNGGNAGYAAYGGNGCNGGNTAYGGNGGNGGNTAYGGNGGNGGNTAYGGNAGYGGNGGN AGYGGNCAYGGNGGNAGYTAYGGNTCNGGNAARGCNGTNCCNAGYAARGTNACNTAYGCN CAYGGNTAYGCNAARTCNCCNYTNATHACNTTYGTNAARGGNTTYAARCCNGGNAARATH TAYGTNGAYCARGGNCAYGTNATHMGNAAYTAYTTYMGNCAYGGNACNTAYCARGTNGCN YTNCARCAYTAYAARYTNATHCCNTCNGTNAARGTNGTNCCNTAYACNACNTAYAARCAR TTYGGNATHGGNGARAARGTNCARGCNACNTAYAARTAYAARGCNGTNATHTGYAARTCN TGYTAYCAYGGNTAYCCNAARATHGAYGTNTAYGARATGAARAARCCNTAYAGYTAYGTN GCNMGNMGNTTYATHTAYYTNCCNAAYCARTAYAAYYTNGGNGGNAGYGGNCARTCNGGN TCNTAYGGNAAYTAYGGNTCNTAYGGNTCNGGNAGYTAYGGNAGYACNGGNAGYGGNTCN ------GGNTAYTCNACNAGYTAYGGNAAYGGNGGNTTYGGNGGNGGNTAYGGNAGYACN GGNGGNTCNTAYGGNGGNMGNGGNTAYGGN---------------------------ACN GCNYTNGCNATHGTNCCNTAYCARGARGAYAAYYTNYTNCCNCAYCARAARAARAAYMGN ACNTTYCAYATHGCNGGNCAYTAYTTYCARATHMGNCARGAYTGGAAYAGYGGNGGNGTN GCNGCNGTNGTNTGGGAYGCNGCNTCNGTNYTNGGNGARTAYYTNGCNTCNAAYTCNCAY YTNGTNCARGGNAARMGNGTNYTNGARYTNGGNGCNGGNACNGGNYTNGCNGGNATGGTN TCNTCNTTYYTNGGNGCNAAYGTNATHGCNACNGARMGNACNGARGCNATHCCNCAYYTN YTNTCNACNATHTCNGARAAYAARGGNGARAARAAYTGGAGYATHGARACNAARACNYTN GAYTGG------------------ACNCAYGAYATHGAYCCNGAYTTYCAYYTNATHATH GGNGCNGAYATHGTNTAYATHGARAGYACNTTYTCNCAYYTNYTNAARACNYTNAARGCN GTNGCNTCNTCNCCNAARACNAARGTNYTNYTNTCNTGYMGNATHMGNTAYGAYMGNGAY YTNCAYTTYTTYGAYATGYTNAARGARTTYTTYCAYGTNACNGARATHTTYTAYGAYAGY CARMGNGAYATHAARATHTTYTCNGCN---------GARYTNATHACNCAYCAYGGNGGN TGYCAYTGYGGNGCNGTNMGNTAYTCNGTNCARGCNCCNGCNGTNYTNGAYGTNGTNATH TGYAAYTGYAGYATHTGYACNAARAARCARAAYMGNCAYTTYATHATHCCNAARTCNCAR TTYAARYTNYTNCARGGNAARGAYTCNYTNACNACNTAYACNTTYAGYGCNMGNAARGCN AARCAYACNTTYTGYAARATHTGYGGNGTNCARTCNTTYTAYACNCCNMGNTCNAAYCAR GAYGGNTAYGGNATHATGCCNCAYTGYYTNGAYCCNGGNACNGTNAARTCNATHAAYTAY TTYAAYTTYGAYGGNGTNAAYTGGGARGARCARATHAARACNTCNAAYATHGCNGARTAY TCNAARTCNGAYTCNCAYYTNGTNTTYACNTAYGGNACNYTNAARMGNATHGARCCNAAY TAYGARCARATGACNATGGARGGNACNGGNACNGCNGTNTTYATGGGNGTNGCNGARACN GTNGARAARTAYCCNYTNGTNGTNGCNTCNAARATHGGNATHCCNTTYATGATHAARTAY GARGGNCAYGGNGAYAARATHCARGGNGARGTNTTYGARGTNGAYGAYACNAARYTNGCN CAYYTNGAYMGNTTYGARGGNCAYCCNAAYYTNTAYMGNCARGARGTNGAYGTNGTNATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CCNYTNYTNACNTTYGGNATHATHGCNGAYGTNCARTAYGCNGAYGCN GAYGAYGGNACNGAYTAYTCNAARGCNMGNACNMGNTAYTAYMGNAAYGCNYTNAAYYTN YTNAARAAYGCNATHAAYGARTGGAARMGNTGYTCNGAYTCNATHTCNTTYGTNYTNCAR YTNGGNGAYYTNATHGAYGGNAARTGYAARGGNGGNYTNAAYGCNAGYMGNAARGCNYTN TCNACNGCNYTNATGCCNTTYAAYTCNYTNMGNATHCCNGTNTAYCAYYTNYTNGGNAAY CAYGARTTYTAYAAYTTYTCNMGNTCNTTYTGYYTNAARTCNTCNYTNAAYAGYTTYYTN TCNACNGARATHACNTGYCARACNGAYTGY------------------YTNTTYMGNACN TTYYTNCCNCAYCCNAARYTNMGNGTNGTNYTNYTNGAYACNTAYGARGTNAGYGTNYTN GGNTAYACNGAYGAYYTNGARAAYGARAAYTAYGTNAARGCNYTNTCNYTNYTNCARGCN AAYAAYCCNAAYGCNGARAARAAYGAYACNACNGGNYTNGARGGNGCNGARMGNMGNTGG GCNGCNTTYAAYGGNGGNGTNAGYGARAARCARYTNGARTGGYTNGCNCARGTNYTNGAR AARGCNCARAARAARGARGARAAYGTNATHGTNGCNTCNCAYGTNGGNACNTAYCCNTCN YTNCCNAARAAYTAYTCNATHTGYYTNGCNTGGAAYTAYCARGARATHYTNGAYGTNYTN CAYAAYTAYAAYTGYGTNATHGCNGTNYTNGCNGGNCAYGARCAYGCNGGNTTYCARCAY YTNGAYGARCAYAARGTNCARCAYATHTCNTTYCARGGNGTNGTNGARACNCCNCCNGGN AAYAAYGCNTAYGCNACNGCNMGNYTNTGGAAYAAYTCNYTNACNATHACNGGNGTNGGN MGNGTNCCNAGYTTYAAYATHTCNYTNMGNTAYCCN------------------------ ------------------------------------------------------------ ---------------------AARACNYTNCAYAAYGTNAAY---ACNGARGARTTYTTY GTNGARCAYGARGCNGCNTCNATHAAYAARYTNTGYCARATGMGNMGNGAYMGNACNCCN GTNCARTAYATHATHGGNGARTGGGAYTTYGAYGGNYTNACNYTNGARATGAARTGYCCN GTNYTNATHCCNMGNCCNGARACNGARGARYTNGTNGCNTAYTGYMGNMGNATHATHAAY CARGAYYTNACNACNCAY---------CAYCARCAYCCNATGYTNGARYTNGGNTGYGGN AGY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARAARCARYTNAARGCNATHAAYAAYAARATHAARACNATGGGNCCNGGN TTYCARYTNGAYGAYGARGCNGCNGGNATGAARAARCARYTNATHCARMGNTTYAAYTGY YTNTCNTGYGAYAARCCNGTNGAYGTNATGCCNCAYGGNCCNATHCCNTCNATHCCNGGN AAYTAYGGNYTNCCNAARTCNAARTCNCCNMGNCCNTAYACNACNTTYGARYTNGAYCAR ATHMGNCARCAYGCNMGNAGYYTNGGNATGAGYGCNGARATGGCNGAYTAYTAYGCNCAR GCNMGNCARTGYGGNGGNCAYCAYACNATGACNCAYCCNACNAARMGNTCNACNAARYTN AAYCAYYTNGGNCARATHTTYMGNGARGARGARACNATHYTNCCNYTNTTYAARGAYGAR GTNGAYGTNCARGGNGCNGAYGGNCAYATHTAYAARGGNMGNATGAAYTCNAAYMGNYTN GARGCNAARYTNCCNGTNAAYATGACNAAYAARCARMGNTCNCAYCCNTCNTAYATGGAR CCNAARGCNCCNTCNCCNCCNCCNYTNAAYMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGTTYAARAAR ACNAARGCNAARGTNYTNCARAAYGGNAGYMGNGARTCNGTNGAYAGYCARATHAGYAGY TCNAGYGCNAGYAAYGARAAYYTNTCNCAYAGYTCNAARGARAAYAARGAYACNGTNGAY AARATHYTNCAYCARAARGTNCAYTTYCARGTNTAYTTYYTNGGNYTNGTNCCNGAYATH AAYTTYACNAAYTCNAARAARMGNGAYACNGARGCNCARYTNATHGAYATHGTNGARGAR TAYCARATHGAYGAYAARYTNCARGTNGCNGCNACNGAYGARAAYAARGTNGTNATGAAY ATHTCNMGNCAYGGNATHAARGTNYTNGAYGTNGCNGGNAARGARGTNYTNCARMGNCAY CCNYTNCAYACNATHGCNCARYTNACNGARTAYAAYGAYGGNTTYGGNCARCARAAYATH GCNGTNAARATHGGNCARGTNGGNAARAAYGTNTAYCAYTGYTAYGTNTTYCARTGYCAY TCNGAR---------ATGMGNGAYTTYATGATHGGNYTNTGYYTNGCNGTNAGYTCNTCN ATHTTYATHGGNTCNAGYTTYATHTTYAARAARYTNGGNYTNYTNMGNTAYGCNMGNAAR GTNAGYGTNMGNGCNGGNCARGGNGGNTTYGGNTAYYTNMGNGARTGGATGTGGTGGGCN GGNATGATHYTNATGACNGTNGGNGARTTYGCNAAYTTYGCNGCNTAYGCNTTYGCNCCN GCNACNYTNGTNACNCCNYTNGGNGCNYTNAGYGTNATHGTNAGYGCNGTNYTNTCNGCN MGNGTNYTNAARGARAARYTNAAYATHYTNGGNAARGTNGGNTGYGTNYTNTGYATGYTN GGNTCNACNYTNATGGTNATHCAYTCNCCNAARGARCARGARGTNCAYGAYGTNGARGAR YTNYTNYTNAARATGAARGARCCNGGNTTYATHATHTTYGCNYTNGTNYTNYTNACNACN TCNYTNGTNATGATHTTYTAYTTYAGYCCNMGNTAYGGNCAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYGARGCNACNYTNGTNMGNMGNGARAARCARATHGTNTAYGGNAARTCNACN CAYTCNTAYAARATGTAYAARGARAARGTNGCNATHGARGAYMGNYTNCCNGAYMGNAAR GTNCAYCCNMGNACNCCNGTNAARACNCARAARTGYAGYMGNMGNAAYTGGGAYGCNCAR ATHAARGCNTGG------------------------------AGYCCNTCNACNYTNAGY ACNTCNCAYTCNGTNAARCCNGTNGTNAARTCNTCNCCNYTNAARATHACNACNAGYACN GTNACNACNAGYTCNGCNCAYAARTCNGGNMGNACNAARCCNTCNACNTCNATHATHATH AARCCNAARGGNTGYGTNTAYCCNYTNGCNGARTCNGTNTGYCAYGARYTNGAYGTNTCN GAYATHATHATHCCNCCNCCNATHAARACNGARGAYGTNCCNYTNCCNCCNGGNAGYCCN AARGAYAARACNTCNAARAAYAARCARGAYTCNCARGAYATGACNGARGAYATHACNAAR ATHYTNYTNCCNGAYAAYCCNCCNCCNACNGARTCNAARAGYAARGAR---CCNGTNGAR YTNGGNAARGGNAGYGTNTCNTTYTCNTTYAAYAAR---AARAGYAARATHGCNAGYATG TCNGCNTTYAAYCARGARGARGCNGAYCCNATHGARATGCCNCCNAGYMGNCCNYTNACN ATGATGGAYAGYATHGARGARGARAARAARYTNATGAAYYTN------------------ ------------GARGARYTNGARGGNGGNTCNACN------------------------ ------GARTCNAGYAGYACNAAYCCNCCNAARCCNMGNYTNATGGARGAYTTYGTNCAR GTNACNYTNATGAARGARGGNGCNGGNGARATHCCNTGGCCNGTNGARACNATHAARTAY ACNAAYACNYTNCCNAGYATHCAYTAYTCNTGYAAYCCNATGCARTTYGAYTTYAARAAY ATGYTNAAYGGNGGNGGN---------------GGNGGNGCNGGNGGNGGNGAYGCNGTN AARAARTCNGGNGAYAAR------------ACNGARAARGGNGAYAARGARACNAARCAY AARMGNAARCAY---TCNAGYMGNAARAARMGNAARAARAARGGNGGNGARGGNAARGAR AAYGTNGARGGNGCNGARAARGARACNGGNGARGAR---GGNAARGARAAYGCNCCNCCN GGNGARAARGGNGARACNGAYAARAARGARAARMGNAARAARMGNAARAARMGNAARAAR CAYMGNCAYAARAGYAAYAARAARACNGARGGNGARGGNGTNGARGGN---GARACNAAR GGNGARGGNAAYGARGARAGYAARTCNCAYAARMGNTCNMGNMGNAARMGNACNCAYAAR GARMGNGAYGARACN------AARGAYAARGCNGARGGNGARGGNAARGGNGARGARAAY GARGARGTNATGGTNAAYGGNAARCCNAARTCNTCNACNCARMGNAGYAAR--------- CAYAARCAYAARMGNAARCAYMGNMGNMGNMGNGGNGARMGNTCNGARAARGCNAARGCN ATGAGYGCNTCNGARAARGCNAARGTNGARAARAGYGGNGARTCNGTNAAYGCNAAYGAR CCNAARGTNAARATHGAYTAYGAYGARGAYGAYGAYGTNAAYATHCCNACNGAYAAYGAR CARGAYGARACNGGNGARCCNAARATHAARMGNCCNTGYMGNTCNMGNAARMGNCAYCAY MGNAAYAAYACNCAYCCNTCNGCNYTNAARGARATHGARGTNAARGTNGARAAYCARACN CCNAGYGAYAARGGNACNACNYTNAARACNCAYAAYTCN--------------------- ------------------------------------------GTNGARGGNTCNYTNGTN AARGAYTGYAARYTNGARCARGGNAARATGYTNAAYGGNGAYATHAAYGGNGGNMGNAAR MGNGGNACNAGYCAYTCNAGYGCNGAYGGNGCNACNCCNGCNAARGTNAAYAARAGYGAR AARGTN---------GARGAYACNTGGAGYAARATGGARGGNYTNTAYGARGAYAARGGN GARGARGGNTCNAARAGYAARTGGGAYACNAGYGAYAGYGARGGNGARGAYGTNYTNCAR AARACNYTNGAYGCNAAYGCN------------AAYGARGARGAYAARGTNAARYTNGAR YTNYTNCARAARCCNACNAAYGGNAARATHCCNYTNACNAARGCNATHYTNGGNACNAAY GGNTTY---------------------------GGNCAYYTNAARCAYCAYACNTCNTCN YTNCCNGCNAAYAGYAAYCAYATHAARAARGAYGGNGTNGAYGGNGTNAARAGYGARAAR GTNGARGARGGNCARGAYGGNAARACNAARTCNACNGGNAARTCNCARMGNGARGGNMGN ACNAARAARMGNAGYAGYMGNAARTCNTAYTCNTCNTCNGARTAYTCNTCNCAYTCNMGN TCNTAYTCNMGNTCNMGNTCNGGNTCNTAYMGNAGYTAYTCNGAYGAYTCNMGNTAYAGY GAYTCNAGYMGNTCNCAYAGYMGNTCNACNMGNAGYTAYAGYMGNAGYMGNTCNMGNMGN MGN------TAYMGNMGNMGNTCNTCNTCNAGYMGNGGNMGNAGYTAYAGYTAYAGYAGY MGNAGYAGYTCNAGYMGNTTYMGNTCNMGNTCNTAYTCNMGNTCNMGNAGYTAYTCNMGN TCNMGNTCNMGNAAYMGN---AARTAYCAYAGYCAYTCNMGNAGYCCNTCNAARMGNMGN AGYACNAARYTNAARMGNATHYTNAARTCNCCNYTNGTNCCNGCNCCNGTNACNYTNATH ---GTNGCNCCNGTNACNGGNTGYACN--------------------------------- ------ACNGGNGTNGGNGGNAGYGGNGGNGCNGCNCCNGAYGAYATHCCNYTNCCNGTN AARGAYTCNTCNAAYCCNTCNGAYACNATHACNAGYCCNAARAAYGAYGGNCARCARTCN GTNYTNACNGAYATHCCNYTNCCNACNCARTCNACNAARCCNGAYAGYTCNGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNMGNAARYTNGTNGARTGGGCNATGGARAAYYTNCCNAAYGTN GTNCCNAGYTCNGTNTTYCARTGYTTYATHGARATGGTNCAYGTNCCNGARGGNGTNACN AAYTAYCARGARGCNYTNCARGAYGCNGAYGARGARAAYATHMGNACNTTYTAYGTNYTN AAYYTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATGGGNATHAARGAYYTNTGGAAYYTNYTNAGYCCN GCNAARTGYGAYACNAAYYTNAARAGYTTYCAYGGNCARATHTTYGCNGTNGAYTTYAGY ATHTGGYTNGTNCARTGYAAR---------ATGCCNTTYCCNTAYMGNTCNATHTTYTAY MGNATHYTNGAYYTNATGAARCAYGGNATHACNCCNGTNTTYGTNATHGAYAGYYTNCAY GCNTCNCCNATGAARAAYMGNGARMGNGGNAAYGARTTYTCNAARYTNGGNTTYAARTGG AARAARGTNYTNGARGCNATGGGNTTYTGYGTNATHCARGCNAARGGNGARGCNGARAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AARAARAAYAGY ATGACNGARAARYTNACNATGGTNAARAAYAAYGTNTGYGARAAYCAYTAYCARATGGCN MGNGCNACNYTNGAYMGNCARAARGCNAGYMGNYTNAARCARYTNCAYGAYCAYTCNAAY MGNYTNMGNCAYCARGTNAARYTNYTNGAYYTNGAYMGNCARMGNCAYAAYGTNGTNGTN AARAARMGNYTNGARCCNCAYAARGAYCAYAGYTAYGAYGAYGGNYTNATHCAYAAYACN GARMGNMGNYTNGGNGCNAAYATHGCNTCNTTYTAYYTNGARAARAARYTNAARTAYCCN ATGMGNATGMGNTCNGTNCARGAYATHMGNGTNACNCCNACNATHTCNMGNGCNMGNGCN ACNATGMGNGCNAGYGAYYTNAAYAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGGAR GCNGGNAARATHTCNMGNYTNMGNGAYGARCARGARAARGCNTTYTGYGAYACNGARGAR CARATHAARAARTTYGARAAYTTYAARTCNGAYTAYAARGCNYTNCARACNMGNYTNAAR ACNYTNCCNGAYAARYTNTCNCAYGAYATHATGGTNCCNTTYGGNAARATGGCNTTYATG CCNGGNAARATHGTNAARACNAAYGARATHYTNGTNYTNYTNGGNGAYAAYTGGTTYGCN GARCARTCNGCNAARCARGCNAGYGARATHGCNGGNMGNMGNATHACNGARYTNGAYAAR MGNATHGAYGGNYTNAARCARCARCARMGNYTNYTNGARACNMGNYTNGGNTTYACNTCN GARYTNAARAAYATGTCNCARGGNTCNGGNGAYTAYAARGARATHGTNGARGARTAYAAY GARGARAARGARAARYTNTGGGAYGARAARCAYAARGARAGYGTNMGNMGNCAYCAYGAR CARYTNMGNAARGARAARGAYTCNTCNAAYAAYACNAARACNATHATHGTNYTNCCNACN CCNTCNCCNATHGGNGAYAAYYTNTGGTCNMGNYTNGARGARYTNGARAARCARGARGAY GARMGNGGNGARYTNAAYAGYTCNGARGTNTCNGAYGARGAYGARMGNGGNTCNACNYTN GTNGARAARTCNGARTCNGGNACNCARGGNMGNAARGTNGTNTGGGARGAYGAR------ ---AARGGNAAYTCNAAYGAYAGYGAYGAYGAYGARGARGARGARGARATGAARGCNAAY GGNGCNGTNGCNGTNGAYGAYGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNCCNCCNAAYYTNAAYGTN TTYAARYTNAARTAYGCNGGNYTNTGGTAYCARATGTCNGCNYTNCAYATHAAYGARAAY AAYACNYTNGARCAYYTNGAYYTNAGYYTNAAYTAYATGCCNACNYTNAARGGNCCNTTY ACNGGNYTNAAYAAYYTNAARACNYTNATHATHCARGGNTGYMGNGTNCARTAYATGCAY MGNGCNTTYTTYTCNTAYYTNCCNMGNYTNGARTAYYTNGAYYTNAGYGGNAAYMGNATH GGNGGNAARAAYAGYTAYAGYYTNTCNTTYCARCCNTTYMGNTAYYTNCAYAGYYTNAAR TAYYTNGAYATGTCNTCNAAYAAYATHTTYAAYATHAARCAYGAYTCNTTYYTNGGNYTN TCNCARYTNAAYCARYTNGAYYTNTCNCAYAAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ACNTCNGTNCCN------TCNMGNAARACNTCNGCNYTNCCNCCNCCNMGN AARATHTCNAAYGGNGCNGCNMGNACNMGNAARACNACNYTNATGYTNTTYATHATHAGY GCNGTNTTYGTNGCNAGYTTYYTNCCNCAYYTNATHYTNAARGCNYTNCARGCNGTNAAY AARGAYTTYCCNTCNAAYGARTCNTAYAGYCARATHATHYTNTAYAAYGTNTTYGTNMGN TCNTAYTTYTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNAAYTCNATHAGYCARGAYACNCCNTTYTGGGAYMGN CAYTTYMGNGGNAARAGYGARATHTCNTGGATHGARTTYMGNGAYAARTTYATHAARGAY TAYGGNGARAARATHATHGARGGNTTYTCNGARGGNATHGARGARMGNAARAAYYTNTTY ATHAAYYTNATGTAYAARGAYGTNTTYAARGGNAARAARATHGTNCARMGNTCNACNTAY GARAARTTYAGYGGNGARTCNCAYCCNCAYGCNTTYTTYATHGCNATGCARGARTAYATH ATGGCNTAYTCNTCNYTNMGNGARATHYTNAGYATGGAYTGYAGYYTNMGNATHTCNACN ATHCARAAYYTNGGNAAYTAYMGNTTYCCNGTNATHGTNTCNGGNYTNACNGAYATGYTN AAYGAYGARGAYCCNAAYATHMGNTCNGTNGCNGCNATHGCNYTNGCNCAYGCNGGNAAR AARAARACNTCNACNGTNGAYAARATHATHCCNYTNYTNGARGAYGARGAYMGNYTNGTN MGNGARAGYGCNYTNYTNAGYATHGGNTAYYTNMGNTCNACNAGYGCNGTNTCNTAYGTN GTNGAYMGNTGGMGNAAYGAYCCNATHTCNACNGTNMGNGARGCNGCNGARYTNGCNYTN AGYMGNATGGAYGCNCARAGY---------------------ATGAARGTNGCNAARGTN YTNTCNTCNGARATGAAYGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHGAR GARGTNGARAARAARGTNAARGARAGYGARGAYAARATHGAYGARYTNGARMGNAARGAR MGNYTNACNGARYTNAARGAYAARGARMGNGARGARATHCARAGYGARAARGARGARYTN GAYAARCARGTNAARMGNTAYAARAGYGARYTNACNGGNYTNMGNTGGCARAAYTGGAAR AGYACNYTNGTNTCNATHATHATHTTYGCNGTNTGYTAYTTYATHTAYAARTAYTTYTTY GCNACN---------------------------------------GTNCCNAGYCCNAAY YTNATHAAYTCNACNTTYTCNCCNAGYCCNCAYTCNATHTCNATHTAYGARCAR------ ---GAYMGNYTNGGNYTNTTYTCNGGNGAYTCNAARATGAGYATGAAYAAYACNATHGAR ATHCARTGYGGNGARGARAAYCAYCCNYTNGAYGAYCAYTTYGARGAYAGYTCNYTNAAR ------ATHACNCCNGARYTNYTNAGYTCNATGACNAAYACNTCNGTNGCNACNGGNTTY GGNYTNCARTGGGGNAAYAAYAARYTNAAYYTNTCNGAYTCNCARGGNATHATHTCNATH GAYCARTCNTTYCCN------------YTNGGNATGGAYTCNGAY------TAYYTNTCN GAYYTNYTNAAYATHGAYTCNAAYGAYAAY------TTYGAYTTYGAYTTYATHACNAGY AAYTCNTCNTCNACNTGYCARACNCCNATHCCNTCNYTNTCN------------------ ---------------GARTCNAARGCNGAYTTYCARGARGTNMGNAAYAAYAARGTNATH TTYTCNAGYTCN------------------TCNYTNACNTCNGAYAAYAAYAAYATHGAR CARGAYTTYAARCCNAARMGNCAYCARTTYCCNCCNMGNAARTCNGARCCNCCNTGYGCN GTNCCNCCNGTNATHATHAARGARGARATHGAR------------------------AGY TAYCCNAAYATGCARGGN---------------CAYTGGYTNYTNACNAARTCNATGAAY ---------------------------GTNAARCARGARGAYGGNAAYMGNTTYAAYAGY TTYYTNACNGARYTNCCNCCNCARACNGTN---CCNTCNGTNAARTTYCCNGARCAYATH GGNTGYGAYACNGTNAARATGGARTCNCCNGAYTCNAGY---MGNAARMGNGTNTTYACN ATGGARGAY------GARATGAARCCNYTNGAYYTNCCNCCNACNGGNCARTCN------ ---------------AARMGNMGNMGNTAYGAYTCNGGNAGYTCNTGGCAYACNTCNGAR GAY------------GGNGAYGARTAYAAYGAYAAYYTNCAYAAYGAYTAYGAYGAYGAY GAYAAYTCNGAYYTNGAYGCNGAYYTNGCNCAYATHGARCCNGGNAAYTGYGARTCNYTN ATHGAYACNGGNAARAARCARAARCARTAYTTYTGGCARTAYAAYGTNCARGCNAARGGN CCNAARGGNACNMGNYTNAARYTNAGYGTNGARTCNTCNACNGAYCCNCAYGTNYTNAGY GGNTTYGARGAYCCNGTNTTYGAYGARGGNAAYACNATHGTNGCNGGNATHMGNCAYGGN GGNAARGCNMGNAARGGNGAYGGNAAYGARGTNACNCCNAAYCCNYTNAARYTNTTYAAR ATHGGNCAYCARYTNYTNMGNYTNAGYAARAARATHAAYGCNTGYCARYTNGGNTCNGAY GTNCCNGTNGTNCARMGNAAYGARGCNMGNMGNGARAARAAYAARYTNGCNTCNMGNGCN TGYMGNYTNAARAARAARGCNCARCAYGARGCNAAYAARATHAARYTNCAYGGNATGGAR ATGGARCAYGGNGARATHAAYAAYGTNYTNMGNAAYATHTGGCCNACNYTNMGNGARAAR GCNAAR---------------YTNYTNCARCARAAYGTNAAYCCNAARACNGAYCCNGAY AAYAGYYTNACNAAYAARYTNACNAGYYTNATHTCNTCNAAYYTNAARAAYMGNGTNGCN YTNAAYACNACNGARTTYGTNAAYAAYGTNATHATGACNGTNGARAARAARGAYYTNAGY GGNGGNYTNAAYATH---MGNTCNMGNAARACN--------------------------- ------------------------MGNMGNMGNGTNMGNAARTCNACNGTNGTNAGYGTN AGYGAYGARGGNACNGAYGTNGGNMGNGAYYTNGARCCNGCNTTYCCNTAYAARYTNGAR AARGCNCCNYTNTCNGCNAARGCNTCNMGNATHYTNAARGARYTNGTNATHGARAARGTN GAYGGNGARAARAGYTTYTTYGARGTNTCNTTYGAYGARTCNATGMGNGARAGYAARTCN GTNAAYMGNTCNCAYTCNGARGAYYTNAARAGYAGYAAYGTNCCNTCNACNACNCCNTTY ACNCCNMGNAARACNAAYGARYTNTCNATHGAYTCNAAYTCNAAYACNTTYTTYACNCCN ACNATHTTYACNCCNYTNTCNTCNACNAAYACNAGYGAYCARYTNTCN---------TCN AGYTTYAARGARCCNGGNATGCCNYTNTCNGCNATGMGNAARGCNGGNTCNYTNMGNAAR AARACNGARACN---------TCNAARACNCCNGARCARATGYTNGGNATHYTNAARAAR AGYCCNATGGTNGARATGACNMGNMGNAARTCNMGNCAYYTNYTNTCNCCNGARATH--- ---AARGGNCARCAYTTYMGNGAYYTNATHACNAAYGARACNGAYMGNYTNTAYAGYYTN TGYCARAARTGGGAYGGNGTNATHACNAARGARTCNAAYYTNGGNGARGARGTNYTNGGN CARATHMGNTCNACNGTNGGNAARGCNYTNYTNYTNATHGARCARMGNTTYAARCARTTY TCNGGNYTNGTNGARAAYTAYGTNTTYGAYYTNGGNGARAARAARACNACNCCNACNGAY YTNCARGGNTTYTGGGARATGATHTAYTTYCARGTNGARGAYGTNGAYGCNCARTTYAAR GAYYTNGARCARYTNCARGARTCNAAYTGGCARGCNAARTCNAARTCNCCN--------- ---------TCNCCNAARATHATHGTNAARMGNGTNACNAARCARAARCCNMGNCARAAR GAYGTNAARTCNAARTTYGCNGCNTTYAARGCNCARYTNCARAARAARAARGCNAAYTCN CCNTCNTCNAARCCNATGGARGAYYTNAARAARYTNAARGTNCCNGARYTNMGNGARGCN YTNAARGGNAARGGNYTNCCNACNTCNGGNACNAARCCNGARYTNATHAAYMGNYTNATG GARGCN------GCNAAYGGNAAYGCNCARGGNGAYGCNGTNATHGAYGAR--------- ------GAYGARATHYTNAARGAYGAY--------------------------------- ACNGAYACNATHCCNGAYGTNGCNGTNGTNCCNACNAARATH---ACNCCNATHACNGTN ACNGARCARTCNAAYAAYAAYAAYAGYMGNYTNGARGAYGCNAGYTCNGARYTNCCN--- ------TCNACNTCNCARGAYTCNTCNYTNGCNAARCCNGCNGARGTNAARACNYTNACN GARGCNGARMGNYTNAARATGMGNGCNGAYAARTTYGGNATHACNTCNGARCARGCNAAR AARGARAAYMGNGCNCARMGNTTYGGNTCNGCNYTNAGYGARAAYAARTCNGGNAAYATH TCNATHACNGCNCCNGCNGCNGAYYTNGAYAARYTNCARAARMGNGCNGAYMGNTTYGGN GTN------------TCNACNAGYTCNGTNACNGARGAYGARAARAARMGNAARMGNGCN GARMGNTTYGGNATHACNGTNTCNACNACNACNACNTCNGCNAARATHACNYTNAAYTCN ACNGAYAGYGARACNGARGCNAARAARAARAARMGNGCNGARMGNTTYGGNYTNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNCCNAARYTNAAYCAYGCNATHGTNTTYTGYGAYGCNAARATGGCN GARGTNYTNCAYTGGTTYGGNGGNATHTCNACNYTNYTNGARGCNGGNGCNACNGAYGTN MGNGARTTYTCNTCNTTYGARAGYGGNAAYGARAAYCARAARAARGCNGTNTTYYTNGTN AGYGGNTGYATHGARGGNGTNACNGARCARATHYTNCARGAYATHATHACNCARAGYCAY TTYCARTAYGTNATHATHTTYACNTCNGCNCAYCCNYTNYTNCAYGCNGAYATHTCNATG GCNGAYGTNGARAGYGGNTCNGCNTTYGAYCARYTNGAYGARYTNGTNYTNGARTGGATG GGNAAYATGAAYTAYACNGTNGARATHGARCAYGTNAGYYTNTTYGCNTCNGARGTNTGY CCNGGNTTYTTYATHATGCCNGGNTTYGTNGAYATGTTYCCNYTNYTNTCNTCNGAYYTN CARCARATHAAYTAYCARTAY---AGYYTNAARCAYTCNAARGAYGCNAARAGYTGYGAY AAYATHAAYGARYTNGCNGTNACNCARYTNCCNGARGARYTNGARYTNCARATHMGNTCN YTNTCNACNTCNYTNCAYGGNYTNTTYCARGCNATGGGNGTNAARGARGAYATHTAYTCN ATHGGNAGYYTNAGYMGNATHATHGCNACNGAYYTNGAYAAYTTYCCNATGGCNAARGCN MGNMGNAARGTNTGYCARTCNMGNYTNTCNYTNGTNYTNGTNGAYMGNACNYTNGAYATH GCNTCNGCNGTNACNAGYCARTCNGARAAYYTNYTNGAYAARGTNTTYAAYTGYYTNCCN TGYYTNAAYGGNCAYMGNATHGAYMGNAGYGTNGAYATGTCNAGYYTNTGYCAYTGY--- ---TAYMGNTCNGGNTCNAGYATHATHYTNCCNGGNTGYYTNGCNCCNTCNAARYTNACN GAYYTNCARAAYCAYYTNTCNACNTGYATHYTNAARAARCARAARGARGCNYTNATGGAY ATHAAYMGNAARYTNGTNGARACNGCNGCNGCNGARAARYTNCCNYTNGAYYTNTCNMGN AARCCNAGYMGNGTNACNGCNGAYYTNYTNGAYTCNACNYTNTCNYTNTTYAARGGNAAR TAYTCNYTNATHCARAARCAYYTNGARACNYTNGARGTNGCNATGGCNACNACNCARACN YTNAARGAYCCNAARATGAAYGGNYTNGAYAAYYTNGTNGCNAARGARAARAAYATHGTN CARTCNATHGCNGAYATHGARATGGGNGAR------GAR---------------GARGAR AGYGTNTAYCCNTCNGCNYTNACNATGYTNTCNAARATHATHGTNGCNGARYTNGARAAR GTNGAYGARGARMGNGARTTYACNATHGAYGAYATHYTNTAYYTNYTNGTNTAYATHTAY TCNYTNTCNGAYGGNAGYAAYGARAAYCARGAYGARATHMGNCARYTNCARGARMGNYTN GTNGARGTNTTYATHAARGAYAARTCNGCNYTNTCNCCNATHGCNCARGGNATHGTNGGN GAYAARGTNAAYGARACNATHYTNGCNGAYCARYTNGARAAYATGTGGGARAARYTNGAR TCNYTNYTNGARGCNMGNMGNGAYYTNAARGARTTYGGNACNYTNGTNGAYCCNGGNGAY TCNATGAGYCCNGCNAAYGTNCARCCNYTNYTNAARCARATHATHGARAARATHGTNGAY CCNACNAARCCNGARYTNCCNGAYATHGARTGYAARTCNGGNGGNYTNAARGAYYTNYTN AARTCNGGNTTYGGNTTYTTYAARAGYAGYGCNAARCCNMGNCCNGGNGAYGCNCCNATH YTNATGATHYTNGTNATHGGNGGNATHACNACNTCNGARGTNAARCARGTNAARGAYGTN GTNGCNAGYGCNAARCCNGGNTTYGARGTNGTNGTNGGNGGNACNMGNATHAGYGAYATH CARAGYACNATHAARTCNYTNYTNGTNAAYGAYAAYATHAAYATH--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNTCNGAYYTNAGYCAR AAYMGNGTNCCNMGNATHGARGTNGAYGARGARCARGTNCCNYTNGTNAARYTNYTNTGY GGNGCNGAYYTNYTNGARTCNTTYGCNGTNCCNGGNYTNTGGAARGAYGARGAYGTNGAR CARATHGTNTCNAAYCAYGGNYTNATHGTNATHAAYMGNGARGGNTCNGAYGCNGCNAAR TTYATHTAYGARTCNGAYGTNYTNTCNAARTAYMGNGARAAYATHATGYTNGTNACNGAR TGGYTNCAYAAYGAYATHAGYTCNACNAARATHMGNMGNGCNTGYMGNMGNGGNGARAGY ATHAARTAYGTNGTNCARGAYGCNGTNATHGAYTAYATHAARGARCARMGNYTNTAYGAY TTYCCNGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARCCNCAYCARAARTGYMGNYTNYTNTGYYTNTTYGCNCARTGYTAYTAYCARGCN GGNYTNCCNCARYTNGCNATHCARGCNTAYMGNGAYGCNYTNCAYATHGAYTGYAARTGY TAYTCNATHYTNTAYCARYTNTCNGTNATHTAYMGNAGYYTNGAYYTNCCNGAYYTNGAR YTNGARTCNYTNAAYYTNTGYGTNATGGCNYTNAARGARGAYGAYGGNAARCARAARAAY CARATHCCNGTNATG---GARYTNGAYGARYTNATHTGGAAYGTNTTYCCNCCNATHCCN MGNGTNTCNTTYATHAARYTNAARGTNGARTTYGCNAARMGNTGYYTNCARTTYAARMGN TAYCARGARGCNGCNGARCARTAYTCNAGYYTNATHCAYATGATHGARGARGAYGAY--- ------AARTGYCAYGARTCNAARGAYCAYAAYCARATHAAYATHGCNGAYATHYTNGTN GARGCNGCNGARGTNYTNYTNATHACNCARCARTTYCARGAYTGYATHMGNYTNTGYAAY CAYGTNCARTCNACNYTNTCNGCNGAYGAYACNYTNYTNAARAAYTGYCARYTNATH--- ---------------------------------------------GARCARTCNGARCCN AGYTCNGCNGARAGYTCNCARTCNGAYYTNTTYGAY------------------------ ------------ATGTTYAGYAAYTCNMGNGAYGAYAGY------------AGYMGNAGY GAYCCNYTNTTYAGYGGNAAYAARATGCARMGNAAYAARGAYCAYTCNMGNAARMGNTTY MGNTCNTGY------------GAYAARACNAGYGGNGARGARGTNCARGGNMGNAARGAY GAR------TGGAAYGAYATHYTNATHACNMGNYTNYTNYTNTGYAARTGYGAYGCNATH GTNYTNTCNTCNGAYTGYACNGAYCARGCNGTNCAYTGYYTNCARCARGCNATHGAYATH YTNYTNCARAGYTCNTAYGCNAGYAARYTNCARGAYGGNGGNGTNTGYTCNCCNCAYCCN AARMGNCARMGNATHAGYTCNGAYGGNAARGCNTCNGAYTCNCAYTCNCARMGNAAYTCN GAYTGYGARGAYCARYTNAARGARTGY---TGGTCNAAYYTNYTNACNGARACNGCNATH MGNYTNGCNAARGCNGGNTGGAARMGNAARMGNTTYCCNTCNGTNATHAAYAGYTGYMGN YTNGTNGARCARATHGAYAARGGNAAYATGAAYGCNYTNTAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GGNTGYTGGATHAARACNMGNYTNGCNTTYAGYAGYATHGGNGTNYTNGTNGGNYTNTCN GCNGGNGTNGTNTTYAGYATGCAYTTYAARAAYTAYAAYGCNGGNATHTGGGGNGTNTGY TCNGGNGCNGCNGCNYTNATHGCNYTNTCNGTNACNATHGCNTTYATHAARMGNTGYTGG GAYAAYAARCCNAAYACNYTNMGNCAYTTYATGYTNACNGGNTGYTTYATHCARYTNGCN GGNGTNTGYGGNTTYGTNGCNTAYATHGTNYTNGCNATHTCNCARAAYCARGCNYTNGAY GCNTAYGGNCAYGGNTTYTAYATHGCNTCNGTNTGGTGYTTYATGACNTGGAARTGGGGN TTYYTNYTNYTNATHTAYTCNMGNTCNTAYYTNMGNTCNTTYATGAGYCARGGNGAYCCN ACNTCNTAYTCNGARCCNGARAARTGYGARATHAARMGNYTNAAYTGGAAYGTNMGNYTN GAYTTYAAYACNCARACNATHAARGGNGTNGCNAGYYTNTAYTTYGARAARAARGTNGAY GAY---YTNAARGARGTNYTNGAYATHMGNGAYYTNAGYATHGARAAYGTNAARYTNCAR GGNTCNGAYAARGAYYTNAARTTYAARGTNGAYAAYCCNACNAAYGTNGAYTAYGGNTCN MGNYTNTCNATHGARATGCCNCCNYTNCARGGNGARAGYTTYACNYTNGAYATHGCNTAY TCNACNTCNAARTCNTCNACNGCNYTNCARTGGATGACNCCNGARCARACNGCNGGNAAR MGNCARCCNTAYYTNTAYAGYCARTGYCARGCNATHCAYGCNMGNAGYYTNTAYCCNTGY CARGAYACNCCNGGNGTNAARTTYACNTAYAARGCNCARGTNGARGCNCCNAARGARATH ACNGTNYTNATGAGYGCNAAYMGN---------GGNGARGTNGTNGCNAARCAYGAYTCN AGYATHACNCAYTTYATGYTNGAYGTNCCNATHCCNAGYTAYYTNYTNGCNATHGTNGCN GGNGAYYTNGARTCNMGNGAYATHGGNCCNMGNTCNAARGTNTGGTCNGARMGNGARATG GTNGAYGCNGCNGCNTAYGARTTYGCNGAYACNGARTCNATGYTNAARACNGCNGARGAY YTNATGGGNCCNTAYGTNTGGGGNCARTAYGAYYTNYTNGTNYTNCCNCCNTCNTTYCCN TAYGGNGGNATGGARAAYCCNTGYYTNACNTTYGTNACNCCNACNYTNYTNGCNGGNGAY MGNTCNYTNGTNAAYGTNGTNGCNCAYGARATHTCNCAYAGYTGGACNGGNAAYYTNGTN ACNAAYGCNAAYTTYGARCAYTTYTGGYTNAAYGARGGNCAYACNGTNTTYTTYGARMGN AARATHCAYAGYAARYTNTAYGGNGARGCNAAR---MGNCARYTNCAYGCNCAYGGNGGN TGGYTNACNYTNAAYAARACNGTNGARCARYTNACNGARGAYGGNCAYGCNCCNTAYACN AARYTNGTNCCNGARYTNTGYGGNGTNGAYCCNGAYGARGCNTTYTCNAGYGTNCCNTAY GARAARGGNTTYGCNYTNYTNGARCAYYTNGARMGNATGYTNGGNGGNCCNGGNGTNTTY AAYAARTTYYTNMGNGCNTAYATHGARCAYTTYAARTAYAARTCNATHMGNACNCARGAY TGGAARGAYTTYYTNTTYAARTAYTTYTCNTCNACNGARGAYCARGARAARYTNGARAGY GTNGAYTGGGAYCARTGGYTNTAYGGNGARGGNYTNCCNCCNTTYACNCCNAARTAYGAY ATHAGYYTNTCNAARACNAGYCARAGYYTNAGYCARMGNTGGATHAGYGGNTCNGAR--- AAYGAYGARACNTTYTCNGTNTCNGAYATHAARGARATGAGYAGYGAYYTNATHGARGAY TTYYTNTCNACNGTNYTNYTNGCNAARCCNGCNGTNCCNYTNAGYACNGTNCARCARATG GARGCNGTNTAYCAYTTYAAYGAYGTNAARAAYTCNGARATHMGNTTYMGNTGGYTNCAR YTNTGYATHCARTGYMGNTGGACNGCNGCNATHGAYCAYGTNATHAAYTTYYTNAAYGAR CARGGNMGNATGAARTTYGTNGTNCCNYTNTAYMGNTCNATGAGYAARTGGGARGARGGN MGNAARCAYGCNTGGAARAAYTTYATGGAYCAYAARTCNGARATGCAYAGYACNACNGCN AARAARGTNGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CCNCAYYTNGAR GGNGARAARYTNAGYAARGCNGCNATHYTNCARCARAGYATHGAYCAYYTNACNAGYYTN GARAARGAYAARAGYMGNYTNCARATGCARYTNGAYMGNACNGCNMGNYTNYTNGTNGAR YTNGGN---CARGAYMGNGTNYTNGTNGAYTCNTAYGTNACNAAYACNCCNCCNCCNTCN AARMGNAARAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGAYAAYCAYGAR GARATHYTNGAYGCNYTNACNTCNYTNGGNAARAAYCCNAAY---TCNGARATHCCNCAR ATHYTNGARCARTAYYTNAARTCNGTNGCNAARAGYGGNGARACNYTNTTYCCNTGGGCN CARYTNAARCCNYTNATHYTNMGNAARATGGARYTNGTNATHYTNGARYTNMGNMGNAAY YTNGCNTCNGARAAYATHCCNACNMGNCCNAAYGTNGARAAYGTNMGNTTYGAYGTNATG CAYGCNMGNATHATHGAYTCNYTNCAYAARTTYAAYGGNGCNCCNTTYACNATHCARMGN YTNTGYGARYTNYTNATHGARCCNAARMGNCAYTAYAARMGNAGYGAYAARTTYATGMGN GGNYTNGARAARAAYGTNYTNGTNGTNAGYACNGTNGAYCCNTTYGGNMGNAARGTNGTN TGYGARTCNGGNAAYAARCCNGTNATGAAYGGNGTNYTN---GAYGTNAAYGGNTCNTAY YTNTCN---MGNGAYGGNGGNYTNAGYGTNCCNYTNCCNCCNGTNCCNGGNTGGGTNAAY ACNCCNGCNTCNTCNACNTCNTCNAGYMGNACNACNTCNAAYAAYCAYAARAGYYTNATH GGNCCNAGYAAYTCNCARAAYTCNGAYAARGARGGNGARGTNTCNAAYAGY--------- ------------------GAYTCNGTNTTYACNCARCARGGNGAY---GTNYTNCCNGTN CARTCNGARGARGTNGTNGARGARACNGTNGTNACNATGGARACNGGNGAR--------- GTNAGYTCNGAYGCNGGNGARGCNATGGCNGAYMGNGAR---------AGYGARCARATH ACNGARGAYMGNGARGCNTCNTCNTTYTCNTCNTCNTCNTCNTCNTCNGARGARYTNTCN ACNTCNTCNGAYTCNGTNGARAAYATGCAYATHTCNCCNTTYGGNAAYGARAAYGGNATG GGNGARGAYACNGAYGARCARMGNCCNTGGGCNGCNTTYGCNCARAAYTCNAARCARGAY GCNGTNGTN------------------------TCNAAYYTNTTYTCNTCNAAYAAYCAR TCNGAYACNCCNGARGGNAAYGARTCNTCNAAYGTNACNTCNTCNTCNATHCCNACNACN AAYGCNTCNCCNTCN------------------CCNTCNTCNTCNTCNACNCCNACNGAY ACNACN------------GCNACNTCNYTNTCNGCNGARAARGAYGCNAGYCAYCARACN GAYTCNAGYACNGCNGAYCCNCCNGTNACNGAY--------------------------- ---------------ACNGCNGAYCARAGYTTYGGNTTYGAYCCNGAYACNGARAAYAAY TCNACN---------------------------AAYACNACNCARGAYAARGAYAARYTN GTNTCNTCNTCNTCNGTNTCNGTNATHCCNGTNGTNAGYACNTCNAAYATHACNACNACN TCNTCNCCNGAYAAYACNTCNACNATHGTNCCN---------ACNYTNTCNGAYCCNACN YTNYTNGTNTCNTCNTCN------------GGNCARGTNGCNACNACN------------ ---------------TAYGCNCARGTNGTNGCNTCNTCNAGYACNGAYAAYCARGCNAAR CAYYTNAGYCAYTCNGARATHTCNCARCCNGAYACN---------TGYGAYAGYGTNGCN GGNYTNGARMGNYTNGTNGGNTCNATGGARCCN------------GAYYTNACNTCNCCN GARGCNTGYYTNTCNTCNTCNTCNTCNTCNTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AGYAARGGNGGNCARYTNTTYGTNGARGARCAYACNATGGARMGNGAYCCNAAY CARGARCAYCAYATGATGGCNCARATHACNATHTAYCARATGCARYTNGGNGGNCAYTAY TGYGGNGARTTYTAYYTNGAYCAYGAYTTYAGYCAYAAYMGNTGYGGNAARGARGGNMGN MGNTGYMGNTTYACNATHGGNTCNMGNCARTGYGTNGAYMGNTAYYTNCARCARTTYAAR GAYYTNTTYACNGARGARGGNAARYTNCARATGAARATHACNATHMGNMGNGCNAAYGAY CCNGCNCCNTCNATHACNTAYACNCAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AGYTCNGARACNAARCCN TCNGAYAARGARCCN------------CCNTCNGAYCARCCNAARACNCCNGARAARGCN AGYGARGCNAARACNAARTCNGGNTCNGCNGAYAAYGCNAARCCNTCNACNTCNACNTCN AARAAR------------TCNACNTCNGCNGGN---TCNTCNTCNCARAARMGNAARYTN AGYCCNGAYTCNGARGARATGAARCARGTNATHAARCAYYTNAARAARCARGAYGARGAY MGNATGAARATGCARGTNYTNGTNTCNAAYTTYTCNGARGARCARYTNAAYMGNTAYGAR ATGTAYMGNMGNGCNACNTTYCCNMGNGCNGCNATHAARMGNYTNATGCARAAYATHACN GGNACNACNGTNTCNCARAAYGTNGTNATHGCNATGTCNGGNATHGCNAARGTNTTYGTN GGNGARGTNYTNGARACNGCNYTNGAYGTNAGYGARAARTGGGARGAYTCNGGNCCNYTN CAYCCNAARCAYYTNMGNGARGCNGTNMGNYTNYTNCAYGCNAARGGNAGYATGCCNTCN ACNAARAGYAARAARCAYYTNTTY------------GCNGCNACNAARGTNAAYATHCCN AGYGCNAAYAARAARGGNCCNGTNCCNGCNATGGTNTCNGGNGAYCCNTCNAARATGTCN MGNGGNYTNATHGTNYTNCARGARTGGTGGGGNYTNAAYGAYCARATHCARGAYTGYGGN AARCARYTNTCN---TCNYTNGGNAAYYTNGTNACNGTNGTNCCNGAYYTNTAYMGNGGN AARGTNACNAARGAYAAYGARGARGCNGGNCAYTTYATGGGNGAYYTNGAYTGGAARGGN GCNGTNGAYGAYATHCARGGNGCNGCNAARTAYYTNAARAGYMGNGGNGTNAARAARGTN GCNGTNACNGGNTTYTGYATGGGNGGNGCNYTNGCNATGGCNGGNGCNGCNYTNGTNCCN GARATHGAYTGYGCNATHCCNTTYTAYGGNATHCCNTCNTCNGARYTNTGYGAYGTNACN ACNATHAARGTNCCNATGCARTGYCAYTTYGGNYTNMGNGAYCARACNGCNGGNTTYGCN TCNCCNGCNGARTGGMGNCCNYTNAARGARAARYTNAARMGNGTNCCNGCN---YTNGAR TTYTTYGARTAYGAYGCNGGNCAYGCNTTYACNAAYAARACNGGNGARAAYTAYAAYCAR GARYTNTGYGAYYTNGCNTTYMGNMGNYTNGTNGARTTYYTNAARAARCAYYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AARATHTCNGCN ACNGAYYTNAGYAAYGTNTGYCAYYTNATHGCNGARAGYTTYTAYCARGAYAARGCNATH AARTCNGAYGARYTNGTNGCNTCNTGGTCNYTNGARGARTGGTGGGARGTNMGNGCNTTY YTNYTNACNGTNATGAARCARGCNATHCARCARCARTGGACNMGNGAYAARATHTCNTCN GARYTNGGNCCNYTNACNGARGCNTTYAARACNGTNATHGCNGAYGCNATHAAYATHCAY MGNGAYTCNTTYAARCARAARYTNATHCARAAYACNACNGCNATHTCNCAYGCNGTNYTN TCNGAYTTYGAYTGGAARYTNCARYTNGCNYTNTCNAGYGAYAARATGTCNAGYYTNCAY CARCCNYTNGTNACNYTNGGNYTNGAYATHMGNCARGCNGAYGGNGARAARAARCAYGTN AAYYTNGARATGGAYAARGCNGARYTNGCNACNYTNATHAGYTCNYTNGARCAYTGYAGY AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYTCNGARYTNYTNGGNGARYTNGGNCARGAR GCNAARATGGTNATGYTNCARTAYTCNCARACNTTYAAYGARAGYGARYTNTAYGARGAY CARGGNYTNCARGCNATHAAYGAYYTNGCNGCNCAYGCNGARTGYYTNGARCAYMGNYTN AARYTNCARAARGARYTNYTNTGYAAYMGNYTNCARYTNATHACNCAYAAYYTNAARGTN GARYTN------------------GGNGGNGARGGNAARCCNYTNCARTTYGCNTCNGAR GTNCAYAAYAARGAYCAYATHYTNGARCAYYTNCARCAYGTNATHTCNACNAARCCNAAR GARCARATGACNGAYGARGARYTNGARTTYCAYTAYTTYAARYTNCAYGAYTAYGAYAAY AAYAAYAARYTNGAYGGNGTNGARATHGGNAARGCNYTNACNCAYTTYCAYGAYGAYACN GGNACNAARGARAAY------------GAYCCNAAYAARGARCCNCCNAARATHTTYACN GAYGARGARATHGCNAAYATHGTNGAYTCNGTNGTNGARGARAAYGAYAGYAAYMGNGAY GGNTAYATHCARTAYTTYGARTTYAARGCNAARCARACNGCNCARCAR---------AAY CCNGAYCARGARCARCARCARCAR------ATGGGNMGNMGNMGNTCNTCNGARAGYGAR TCNAGYTAYTCNMGNTCNAARAARAARAARAARMGNAARGARMGNTCNMGNACNMGNTCN AGYTCNTCNAGYGARTCNAGYMGNTAYTCNAGYTCNAARAGYAARCAYAARAARTCNAAR AARAARCAYTCNAGYMGNAGYCCNAGYAARCAYAGYAGYAGYMGNAGYCAYCAYAARGAR MGNTCNMGNMGNTCNMGNTCNMGNTCNACNGAYMGNCCNTCNTCNMGNMGNTCNMGNTCN CCNGARGTNTCN---TCNTCNMGNTAYMGNTCNMGNTCNMGNTCNGAYTCNMGNAGYMGN ------------------TAYAGYACNMGNMGNTCNMGNTCNMGNTCNTCNGGNTCNMGN GARTAYAGYMGN---MGNMGNTCNMGNTCNGAYTCNYTNGAYMGNAGYAARMGNAARGTN GARAGYTCNYTNAGYMGNMGNMGNTCNMGNTCNMGNTCNGARTCNGGNTCNMGNGGNACN GAYMGNTCNMGNCARACNAGY---CARGARMGNTAYAARGAYGAYGGNAARYTNAAYATH GTNYTNTCNTCNTCNGARAARGTNGARYTNMGNMGNAARGCNATGYTNGCNGCNATGGAR MGN---------GAYAAYTCNTCNCCNTCNACNTCNACNACNACNGGNGGNGGNGGNGGN ATGATGTCNCARGCNGCNTCNGAYATHYTNTCNGCNAARGAYTTYGCNGAYAGYGTNGCN GAYATHGARYTNGAYGGNTTYGTNCCNACNTCNTTYAARTCNTCNGGNGCNMGNATHAAR CCNGAR---CCNTCNGARGTNYTNCARTCNAAYCAYGAYGAYGCNATHTTYGGNTCNYTN TCNACNAGYGGNTTYACNATHAARCCNGAYYTNGAYATHAARCCNATHACNATGGAYGCN GCNTCNATHATGCAYCCNMGNYTNTTYTGYAAYGTNGARGARAARATGGARAARTGGATH GAYMGNYTNTCNTAYYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNTTYCARYTNCCNAAYTTYTTYTGYCCNAAY GARACNGARGCNCARATHATHACNGGNATHCCNGTNAARTCNGTNAGYAAYGCNYTNATH GCNTGYAARATHYTNCARGARATHAARGGNTGYCARTCNGTNATHATHACNYTNGGNCAR TTYGGNGCNGTNTAYAARGARTCNCCNACNGCNGARCCNGTNCAY--------------- ---------------------ATGTCNTTYCCNGGNMGNACNCCNATGGCNATGCCNGGN GGNATGCCNGGNATGGCNCCNMGNATGATG---ACNCCNGGNTAYGCNTTYACNTCNATG GGNATGACNMGNATGAAYCCNATGATGCCNATGCARATGGGNATGATGGCNCCNATGATG CARCCNATGATG---------CARGCNCARATGCARATG---CARCCNCARATGAARCAR GCNCCNMGNTTYATHACNCARGARATH---AARACNGAYAGYTCNGGNGARMGNCCNCCN GTNACNACNGTNTTYGTNGGNAAYATHAGYGARMGNGCNCCNGAYATGATGATHAARCAR ATHYTNCARMGNTGYGGNAAYGTNYTNAGYTGGAARMGNGTNCARGGNGCNTCNGGNAAR YTNCARGCNTTYGGNTTYTGYGARTAYGARGAYCCNGARGCNACNYTNMGNTGYATHMGN YTNYTNAAYGAYTGGTCNATHGCNCARAARMGNYTNGTNGTNAARGTNGAYGCNAARACN AARACNYTNYTNGAYGARTAYMGNAARAARAARCARGCNTCNACNGARTCNTCNGAYAAR GGNGAYTCNGARTCNAARGARGAYGGNAARAARGARGAYAAYGGNGARGAYAARGAYACN GAYTCNGAYAARGGNGARAARGARGARAARGAR------AAY---GARYTNGAYGARAAY ACNCARMGNGARGAYMGNGTNGCNCAYGCNGGNYTNGARGCNATHATGMGNGARTAYGCN TTYGARYTNAAYAARGARCCNGCNAARCCNGTNGAR---CCNGTNCCNGARAARMGNGAR CARCARCCNAARGARAARAARGAYATGATGGTNCAYGCNAARGAYACNGGNTTYGARGAY ATGGARATGGARGAYGARAARMGNGAYATHATHAAYMGNGARATHAAYAARTTYMGNGAY MGNCAYAARGAYGCNGAYGARGCNAARGARAARGAR------AAYAARGARMGNAGYYTN CARMGNGARMGNGARMGNMGNCARGARGARAARMGNCAYMGNGARMGNATGGARAARATG MGNATHGARMGNGAR---------------AAYMGNGARMGNGARAARGARMGNGTNAAY GTNMGNATHTCNMGNTCNAARTCNMGNTCNGCNTCNCCNGCNCCNTCNMGNAAYMGNMGN MGNTCNMGNTCN------------MGNGARMGNAAYAGYMGNGAYAARTCNMGNGARMGN MGNAARGARMGNGARATHGARGARGARGARGARYTNTAYGARMGNMGNAARYTNGARAAR AARYTNMGNGARAARGARGCNGCNTAYCARGARMGNYTNAARAAYTGGGARGGNMGNGAR MGNAARAARGCNMGNGARTAYGARAARGARAGYGARMGNGARGAYGARMGNAARGTNGAR GARACNMGNGARGGNMGNMGNYTNAARGARTTYYTNGARGAYTAYGAYGAYYTNMGNGAY GAYCCNAARTTYTAYAARGGNAGYGCNYTNCARMGNMGNYTNAARGARMGNGARAARGAR AARGARTTYGAYAAYMGNGAYMGNCARMGNGARAARGARGARTTYGARGARATHAARMGN AARYTNTTYGAYGARGGNCAYCCNGAYGCNGARACNGARGTNGCNMGNATGGARMGNGAR MGNGARGARCAYYTNCARCCNCARYTNCARYTNCCNGARCCNAARCARCCNTCNCCNCCN GAYAAYCAYCAYGARTCNGAYTCNGAYCAYTCNCAYCARATHAARGCNMGNAARTCNCCN ---------------------GCNAARGCNTCNGARCAYGTNCCNTCNAGYAARAAYACN YTNCCN---------------------------------------------GARCAYMGN AAYTCNCCNTCNYTNTCNACNTCNCCNATHTCNACNGAYTCNMGNGTN---AGYGCNCCN GGNYTNTGYYTNGAYGARTCNTCNCARTCNTCNYTNCCN--------------------- TCNGTNCCNCAR---GARGARAAYAARMGNGGNATHAAR--------------------- TCNAARMGNYTNGCNCCNGTNGCNAGYCCNGAYTCNTCNAGYYTNCCNGGNCCNCCNACN GCNGCNGAYGGNAARMGNAARAARYTNACNGTNGGNGAYGTNTTYAAYCARGAYGAYGAY GAYAGYAAYGARCCNAARAARMGNAARYTNATHCCNYTNGAYTAYGAYGAYGAYAARTCN AGYCCNTCNGARAARAARGGNTCNTCNGCNGARGARAARMGNCARMGNATHAARCARYTN ATHGARAAYATHCCNACNGCNAARGAYGARYTNTAYGCNTAYGTNGTNGAYTGGGAYATH GTNGAYCARGGNYTNATGGAYAARMGNATHAARCCNTGGGTNACNAARAARATHGTNGAR TAYATHGGNGARGARGARCCNACNYTNACNGARTTYATHTGYTCNAARGTNGTNGCNAAR AGYACNCCNCARAGYATHCARAAYGAYGTNGCNATGATHYTNGAYGAYGARGCNGARGTN TTYGTNGTNAARATGTGGMGNYTNYTNGTNTAYGARACNGARGCNAARAARATGGGNYTN GTNAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TTYGAYCAYATH YTNGCNACNGCNAARCAYGGNGTNAARGAYAARGAYGCNAAYAARTCN---------GAY CARGTNMGNYTNCARTGGGAYCCNGAYCAYGGNCCNMGNGGNGARCCN---YTNACNMGN MGNGCNATHCARYTNGGNYTNMGNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGNATHGCNMGNATGAAYAARGCNAARGARCARGCN GCNAARAARAAYYTNGCNAAYGGNGGNAGYGCNAAYGAYGAYGAYTGGGAYATHGCNGGN GGNGARGAYGAYTTYGARATGTTYYTNGCNAGYGTNAARGCNMGNTCNYTNGCNACNMGN ACNCARGTNAARAAYGGNTCNGGNGAYGGNCAYAGYTCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AAYCARCCNGTNTTYYTNAARGARGCNYTNAARATGGCNYTNMGNCARYTNGCNGTNACN ATHGCNTGYTCNYTNGAYGAYCAYCAYCARGARGTNATHACNATGTGYMGNGARCAYACN YTNCARGGNATHYTNGCNGARGARTCNGTNTAYACNATHTTYGAYCCNCCNMGNTAYTTY TCNTCNAAYAAYATGAARYTNACNTAYAARGGNTCNYTNGARACNAARGARTAYATHATG GAYGARGTNGCNAARTGYATGAAYYTNAAYCCNAAYMGNTTYTGYGTNTTYGCNACNYTN YTNGGNAAYCAYATHYTNACNGAYGARGAYYTNGTNCCNTTYMGNGARYTNATHCCNGCN CCNGARGGNGGNAARCCNMGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYGAYTCNGAYATHCCNCCNYTNGARGAYATGACNGAYATHYTNCAR AARGCNGARYTNATHMGNGAR---------CAYMGNCARGCNTCNCARGAYAARAAYACN AAYCARAGYAARGCNAARAARMGNGCNAARGTNACNAARAARAAYGTNGGNGTNTCNACN ACNACNCCNACNGARAARAAYGCNGGNGAY------ACNAARACNCARACNAARCCNGAY TCNTCNAARGAYGARTCN------------------------------------AARAAY GTNCARGTNAARCCNYTNACNAGYTCNAGYCARGGNATGTTYGGNGGNATGAARAARGGN TTYYTNTTYGGNGGNCCNAGYAARAARACNTCNAARACNAAYCARAARTCNCCNCARACN AAYGTNACNGARAARYTNTCNACNGCNACNACNGCNACNAAYTCNGTNAARGAR------ ------------------------GAYYTNCCNTAYATHTCNCCNTCNGGNAARACNGAR TCNGGNYTNACNTTYAAYGARGTNCARGAYGCNATGTCNGARGCNAARGGNYTNYTNGAY AAYCARGARTGGATHACNGAYGAYTTYYTNAAYAARATHGARAARAAYGARACNYTNYTN ACNMGNTTYAGYGAYCCNCARTTYATGTCNGCNYTNCARGARTTYCARACNAAYCCNCAR GCNGCNATGGCNAARTAYAARGGNAAYACNGARGTNGARAARTTYYTNATGGARTTYTGY GGNATGYTNGGNGAYCAYTTYTCNAARYTNGGNGAYAGYGARACNAARACNCCNTCNAAY AAYAAYTCNAGYCARCARGCN--------------------------------------- ACNGCNGTNCCNACNGTNYTNAARAAYGCNGCNTCNCARAARGARGARAARCARTCNCCN AARATHGTNGARATHGAYGAYAGYGAYGARTCNYTNCCNGCNACNCCNTCNTCNGAYAAY AARCCN---------------------TAYAARACNTCNAAYACNAARGARMGNAGYACN GCNTCNATHCARATH--------------------------------------------- ---CAYCAYCCNCARGARAARGCNGAYATHCARGARGTNCAY---------------CAY ATGGARGAYGAYGAYGTNAARAAYGTNYTNAAYGAYCCNAARGTNATGGARACNYTNYTN GAYCCNAARATHATGGCNYTNATHAARACNYTNMGNGARGAYCCNGARAARGCNCARAAR YTNATHGAYACNGCNGAYACNGAYTTYAARAARAARATHAARYTNYTNGTNTCNAARGGN YTNYTNCARTTYCARATGAAYCARCAYMGNGCNAARCCNACNAAYGTNCCNTCNYTNYTN YTNCARGAYAAYGARAAYGARGTNYTNTTYCARACNYTNGGNMGNYTNTGYGTNACNYTN GCNACNGGNGTNGTNCARYTNTAYYTNGCNGAYCARCCNGAYMGNACNMGNTGGAAYAAR MGNTGYTGYGGNGTNGCNTGYTTYGTNAARGAYAAYGCNAARMGNTCNTTYTTYATHAAR GTNTTYGAYATHAARAARCARCARATGYTNTGGGARCARGARYTNTAYAAYCARTTYGTN TAYAARACNCCNMGNGARTAYTTYCAYACNTTYGARGCNCAYAAYTCNCARGCNGGNYTN AAYTTYGCNTCNGARGAYGARGCNATHAARTTYMGNGARGCNGTNGARGGNAARYTNAAY GARMGNMGNCARAARAARATGGARMGNAAR---CARAARGTNTCNTCNAAYMGNACN--- ------AAYACNGGNCARAGYCCNGGNTCNGCNCCNCCNAARMGN---------CCNAAY GTNACNCCNAGYCCNGCNCCNGCNACNGTNGAYTCNAAYMGNCCNGCNACNAAYACNGCN AAYGCNAARAARGARAARGAYAARAARAAR------GAYGCNAARAARAARYTNACNAAR GCNGAYATHGGNACNCCNTCNAAYTTYGTNCAYGTNAGYCAYGTNGGNTGGGAYCCNGAY AARGGNTTYGAYATGAAYAAYYTNGARCCNGAYATGCARACNYTNTTYCARTCNGTNGGN ATHAARCCNGARGAYAAYGTNGAYAARGARACNYTNGAYTTYATHTAYGAYTTYGTNGAR AARCARGGNGGNATGGARGCNTTYAGYAARGARYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNTCNTCNGTNCARYTN TTYACNATHAARMGNGTNGARGTNYTNACNATHYTNCARYTNTTYAAYATGATHYTNTGG ATHATGGAYGTNCAYTTYAARTTYATGCCNGTNGCNATHYTNCCNGCNYTNATGATHTTY ATHGGNYTNYTNGGNGGNGCNTCNTAYGTNAAYATHTTYTAYGCNYTNYTNCAYGAYGAY AARTTYCCNACNAARGAYMGNGARYTNTGYGTNAAYYTNGTNGGNYTNTTYATHAAYYTN GGNATHYTNYTNGGNACNGGNYTNGAYGTNTCNGGNATGMGNAARCCNTAYAARGGNMGN CARGAYGTNTTYGAYGTNAARGAYYTNGTNACNYTNGARCCNTAYGGNCARTTYAAYGCN TGGTTYGARGAYGCNAARGCNACNCCNGGNATHATGGARGCNAAYGCNATGGCNYTNGCN ACNGCNAAYAAYGARGGNGTNCCNTCNGTNMGNATGGTNYTNATGAARGGNGTNTCNAAR GAYGGNATHGAYTTYTAYACNAAYTAYAAYAGYMGNAARGCNCARGARYTNGAYGARAAY TCNTTYGTNTCNYTNYTNTTYTGGTGGTCNGTNCARAGYMGNCARGTNMGNATHGARGGN AARGTNCAYAARYTNTCNGTNGARCAYTCNAGYAGYTAYTTYCAYTCNMGNCCNMGNTCN AGYCARATHGGNGCNTGYGTNAGYGARAAR---CARAGYTCNGCNATHCCNTCNMGNGAY GTNYTNGAYAARMGNAARGARAARYTNGARACNGARTTYAGYGAYGARTCNATHGARATH CCNAARCCNGAYTAYTGGGGNGGNTTYMGNGTNGTNCCNCAYMGNTTYGARTTYTGGCAR GGNCARACNAAYMGNATHCAYGAYMGNATHATHTTYMGNAARYTNTAYGARGGNGARGTN ATHGAYCCNACNGTNACNTTYCAYGGNYTNGARGGNTGGGTNTAYGARMGNYTNCARCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TGYGGNAARAAYGGNCARTAYGARGCNYTNTAYCAYAARGTNCCNATHYTNTGY TTYCCNYTNTGGGCNGAYCARCAYTAYAAYGCNGARMGNGTNAARAGYAARGGNTTYGGN YTNAARGCNGAYYTNMGNTTYGTNACNGTNGARGARYTNACNCARATGGTNAAYCARATH YTNCARAAYGARACNTTY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARYTNACNTTYGGNATHGTNGCNGCNAAYATHGCNGTNTGGYTN YTNTGGAARGTNCCNMGNATHCARCCNMGNATGATHAGYTAYTTYTCNTCNGCNGCNGCN CAYCCNMGNYTNTCNATGATHYTNAGYAGYTTYAGYCAYATHAGYTTYTTYCAYATGGCN ATHAAYATGTAYGTNYTNYTNTCNTTYGCNCCNGTNGCNGCNAARACNTTYGGNCAYGAR CARTTYTCNGCNTTYTAYATHAGYGCNGGNACNGTNTCNGCNTTYGCNAGYATHGTNTGY CARAARYTNYTNAARMGNCCNYTNGCNATHTCNGTNGGNGCNTCNGGNGCNATHATGGGN YTNYTNGGNGTNACNGGNATHGTNTAYCCNAAYGCNCARYTNCARATHGCNTTYATHTCN GARATHTTYCCNCAYTCNTTYTCNGCNGARTCNGGNATHAARGCNATHGTNYTNTTYGAY YTNATHGGNYTNTTYATGGGNTGGMGNGTNYTNGAYCAYGCNGGNCAYYTNGGNGGNATG YTNTTYGGNATHYTNTAYGCNAARTAYGGNAGYCARTAYYTNTGGGGNAARMGNGAYTCN GTNGTNAARGTNTGGCAYMGNTAYMGNGGNAARCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ACNAARCCNATHCCNTTYGCNGTNGARCARCAYAGY AARGAYATGYTNCARAARAARGARCARAARATHCARCARATHYTNGARGARGARAARAAR GCNMGNGARTTYCAYGCNACNYTNATGCCNAGYGGNAGYCCNGAYGARYTNCCNMGNAAR ATHCARCAYCCNGCNACNGARGCNGARCCNTTYCAYYTNAARGTNGAYCAYMGNGGNGAR AGYTAYCARAARGARYTNAARTCNAAR---ATGGARGARGARAARAARAAYYTNAARGCN ATGMGNCAYTTYCARGCNACNTCNAGYGCNGTNACNTTYAARGCNCCNTTYGTNCCNGAY AARTGYAGYAARCCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CAYCAYGGNTCNAARGAYGAYATHCAYGGNGGNGTNGTNATGGGN GTNCCNAAYCAYTTYTGYGAYGAYGGNCARAAYTTYACNTAYATHGAYTGGAAYATHAAY TCNACNAARGARTAYACNTGYTAYGAYGAY---------------ATHGAYYTNGAYATH YTNMGNGAYAGYTAYCARACNTGYGARAARACNGCNAARMGNCCNATHCAYAARTGYTAY CCNCARACNATHGARTAYACN---GARATHCCNACNAGYGGNTCNCAYMGNCCNYTNTGG CCNMGNTAYGGNGARTAYACNTAYYTNCCNCCNCARMGNTGGGTNCAYTCNYTNGARCAY GGNACNGCNGTNTTYYTNTAYAAYCCNTGYGCNGAYCCNGAYCARATHAGYAARTTYAAR GCNGTNGCNMGNAAYTGYYTNMGNMGNCAYATHATHACNCCNTCNAARMGNATHCCNGCN CCNCAYATGTTYGCNATHGCNACNTGGAARTGYAARYTNGTNATGACNCAYCCNGAYGTN TCNGARATGGTNCAYTTYATHMGNGCNMGNGCNYTNCARGCNCCNGARAAYGGNGCNACN TCNGAYGGNCARTAYAGYMGNGCNYTNATHAARCCNGCNAARYTNGTNAGYGAYATHCAY GARTCNGAYATHTGYCCN---------------GARTGYGARCCNTTYGAYGTNTAYAAR AARCARCARATHGAYGAYGTNATHATHCARGARYTNGAYGAYGCNATHYTNAARGTNGCN MGNGTNMGNAARTAYGARGTNACNAARTGYGTNAARGARGCNGCNTCNATHGCNTCNAAY TCNGTNAARTAYTAYAGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GTNGARGCN GCNYTNGCNMGNTCNGCNCARYTNYTNGARAARGTNACNAARGAYGARATHCARACNGCN YTNTCNGAYTTYAGYYTNTCNACNCARYTNYTNYTNGCNGAYGCNGGNAGYAGYTAYTCN AAYAGYTCNAARTCNTCNAGYYTNTCNGARMGNTAYAAYMGNCAYATHMGNAGYMGNTCN GTNCCNCCNCCNTCNGAYTGYGAYAGYGAYYTNAARAGYTTYGAYACNYTNGCNYTNYTN ACNGGNAARCCNCAYACNMGNCAYAARGCNGCNAGYCAYAAYAARGGNAAYGTNYTNAGY GCNAARATHTTYCCNGAYTCNGCNATHYTNTCNTCNTCNACNGGNAGYYTNTCNTAYGAY GGNYTNGAYGGNGAYMGNTCNTGGGARAARCAYACNAAYAAYTTYAARTCNCCNGTNCCN GTNGGNGGNYTNGAYYTNTCNGGNAARGTNGAYCAYTCNGGNGAYAAYGCNATHAAR--- ---AAYTCNGGNYTNTCNGGNGGNAAYCARCCNGGNAGYATGGARACNYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG CAYYTNCCNGCNGAYYTNAGYGGNTTYACNCCNTTYCARGAYTAYAGYATGTCNGARYTN GGNGCNGCNCCNGGNGAYMGNCCNYTNACNTGYGTNYTNAAYGAYCAYCCNGGNGARYTN GTNAARACNGGNAGYCCNAAYTTYYTNTGYTCNGTNYTNCCNTCNCAYTGGMGNTCNAAY AARACNYTNCCNGTNCCNTTYAARGTNGTNGCNYTNAGYGAYACNAARGAYGGNACNAAR GTNATHATHAGYGCNGGNAAYGAYGARAAYTTYAGYTCNGARYTNMGNAAYAAYACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNTTYATGCAYYTNTAYTTYAARGAY YTNCCNCAYCCNGTNTAYATGCARAARTCNATHAARGARYTNGGNATHGGNACNTAYGAR AAYGTNATHACNGCNACNYTNGAYATGACNYTNATHCARGTNYTNAAYYTNTTYTGYGAY CAYMGNATHTCNGCNYTNCCNGTNGTNGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------MGNAARTTYTCNACNGCNGTN AAYTTYACNTCNGARGARMGNAARMGNAARMGNGARGAYGTNACNAGYAGYYTNACNGCN TCNTCNACNYTNGAYYTNGGNAAYACNTTYAAYGAYYTNGTNGTNCCNGARTAYYTNCCN ATHGGNATHAARYTNYTNAARAARATGGGNTGGMGNGARGGNCARGGNYTNGGNCCNMGN GTNAARACNAARAARAARAARAARTCNGARGTNYTNTCNACNGCNACNACNMGNATHTAY GGNTGYGCNCCNCCNCCNCCNTCNTCNTCNAAYTCNGAYTCNGAYGAYTTYYTNCCNTCN AAYATGGCNGAYATHACNTTYGCNCCNAGYGAYGTNACNCCNYTNTCNYTNTCNGCNAAR AAYGAYGTNAARGGNYTNGGNTAYMGNGGNYTNGAYTCNTCNYTNGCNYTNCCNACNGCN CAYGTNAAYYTNTTYAGYGARCCNGTNMGNGTNAARGGNMGNGGNAARTCNATHAARGGN CARGCNTTYGGNGTNGGNGCNYTNGARGAYGAYGAYGAYGAYATHTAYGGNACNGAYAGY ATHTCNAAYTAYAAYACNACNYTNAARGAYGARGAYGAYGAYAAYGAYAAYCAYTTYGGN TGGACNGCNCCNMGNTCNCAYGGNAARCARAARGTNCCNGTNTCNTAYGTNGGNAARYTN YTNGARGGNTTYACNYTNTCNTCNAARCCNYTNAARCCNGCNAARMGNTTYCCNACNCCN ACNYTNCCNGCNAAYTTYAARCCNTTYCAYTGGGCNMGNMGNAARAAR------------ ---------AARAAYGGNGARGCNACNGGNATGAAYGCNGTNGAYMGNGGNYTNYTNYTN GGNGARACNCCNATHATGGARTCNGTNTTYGAYYTNGTNCCNGCNGCNGAYAARAAYMGN GTNGCNGCNACNCARGARGCNATHAARATGAGYCARTCNYTN------------------ CARYTNAARCARTCNACNCAR------------------------------ACNCARCCN GARGTNGTNCARAARGARACNGARAARCARAARTCNGTNGGNCCNTCNTTYGTNTCNAAR TTYACNCCNGCNGCNGTNGAYTCNGARGAYATHCCNACNACNMGNCCNGCNGGN------ ---------------YTNACNACNCCNTTYGCNYTNMGNCCNTTYCAYAARGAYCCNACN AARCARGARMGNTTYGAYMGNTAYYTNGCNAAYGTNCARAARMGNGTNCCNGAYCCNTAY ACNTCNGTNTCNACNAARGAYATGACNGARTGGGARAARTCNMGNGARAARGARGARTTY AGYMGNTCNGCNAARYTNTAYMGNCCNATGTCNGCNATGATGGCNTCNMGNTTYGTNACN GGNGCNATGYTNGAYGAYAARATGGAYGARAGYGAYACNAARGTNAARGAYGTNGCNACN GAYGARTGYAARGCNGTNGARATGMGNATGTTYGGNAARYTNACNCAYCARGARGTNGAR TGGCAYCCNGAYAARYTNGTNTGYAARMGNTTYAAYGTNCCNAAYCCNTAYCCNGGNTCN GAYATHGTNGGNYTNCCNAAYGTNAARMGNGAYAARTTYTCNGTNTTYAAYTTYYTNAGY ATHGGNGAYTTYMGNCCN---GAYCAYCCNYTNCCNAAYCAYGGNTCNGGNAARGARAAR GARAARGARATHGARTCNCCNAARCAYGAYGCNGAYTTYCCNGTN------AARAARAAR GCNACNYTNTCNTCNATHTTYAARGTNYTNGAYGAYCCNGAYTTYCAYCAR--------- ---AARCCNGAYGCNTCNTCNACNATHTCNCARACNCARAARAARCARGARATGYTNGTN CAYGARGARGAYGAYGAYAARGGNGARGARGARGAYGCN---GGNGTNGAYYTNTTYMGN GCNATHTTYAARAAYTCNGAYTCNGARGAYTCNGAYGAY------GAYMGNCCNGARGTN ATGTCNGAYGTNTCNATGGAYMGNGGNAAYGARGARGAYGARGAYMGNCARAARGAR--- ------------------------------GAYGGNMGNGAYGARCAYAARGAYATGGAR GTNCARATHAARTCNGAYGAYGAYTCNGAYAAR---------GCNGARAARGARTGYAGY CCNAARCAYGAYATGGGNGAYCAYCAYAGYAARATHCARACNCCNCCNTCNCCNCCNCAY MGNTCNCAYGCNGARAAYAGYMGNMGNTCNMGNTGGGARAAYCARCCNAARTCNATHTTY GGNGTNYTNGAYCARYTNGAYACN---------------------------------AAY CCNACNATGATGGCNGCNCCNCCNCCNGAYGAR---ACNGAYGARTAYGGNCCNACNYTN CCNCCNCCNCCNTCNTCNTCNCAYACNGAYTCN---------ACNYTNCARAARGGNAGY ACNTCNTCNACNGAYAARMGNAARGARACNMGNTTYGARGAYAGYGARMGNGAYMGNMGN MGNAARGARAARAARAARAARTCNMGNCAYAARAARAGYAARAARGARAARAARCARAAR AARAARTCNTCNAARTCNAARAARTCNMGNCAYGARAGYTCNGGNAGYGARGCNGAYACN GARAGYAGYGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARMGNCAYGGN GAYYTNGTNATHYTNCCNGTNTCNTGYTTYACNTCNATHGARTGGAARAARACNGGNCCN GAYYTNYTNAARTGYATHAGYAAYACNYTNMGNTGYCARMGNATHGCNCARCAYAGYTGY GTNGCNAAYGAYGGNTAYMGNTCNCCNCARGTNTCNATGYTNYTNGGNAAYGAYGGNAAY GTNATHCAYATHGAYAAYGGNATHAARTAYAGYTTYGAYGTNACNAARTGYATGTTYAGY TCNGGNAAYATHACNGARAARYTNMGNGTNGCNAGYTGGGAYTGYTCNAAYGARATHATH GTNGAYYTNTAYGCNGGNATHGGNTAYTTYACNYTNCCNTAYYTNGTNCAYGCNAARGCN AGYCAYGTNCAYGCNTGYGARTGGAAYCCNGAYGCNGTNACNGCNYTNAARAAYAAYYTN GTNYTNAAYGGNGTNGARCAYMGNTGYACNGTNCAYCCNGGNGAYAAYMGNAARYTNCAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARGCNGGNCAYATGATHYTNAARCARGARCARGCNYTNGGNMGNGARTTYTAYATH AAYGGNATHMGNTTYCCNCAYTAYGTNATHMGNCARTGGGAYGAYTTYCAYTCNAAYAAR GARAARGARAARCARGAYAARGTNAARGCNMGNGCNAARCARACNCARGARGARATGATG TTYGGNAGYMGNTCNGTNYTNACNACNCCNGGNAARMGNAARCARGGNGCNGCNACNACN CCNATGMGNACNCCNYTNAARGCNMGNMGNYTNAAYAGYACNATHAARACNCCNAAYACN ACNGGNMGNYTNYTNCCNACNAGYAARGTNCARCAYAGYACNATGTTYCAYTCNYTN--- ------CAYGCNAARACNCCNATH---TCNACNAAYAARMGNMGNMGNTCNMGNMGNYTN YTNCARAARGCNATHGARGAYCARMGNACNTCNGGNAAY---AARMGNMGNTCNMGNGAY ATHTTYTCNCAYACNACNGTNAGYAGY---GAYCAYCAYTCNTCNTCNYTNGCNTCNGCN GGNTCNTAYAAYGARTTYACNAAYGGNYTNTAYAARTCNAAYTGYMGNAGYAGYGTNGTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGTNGGNTTYATHGTNCARAGYTCN AGYYTNAAYTCNTTYGGNTCNATHTGYTAYTGYGGNATHGTNYTNGGNATHCAYACNTAY GCNTGYTAYAARGAYATHACNMGNTAYCARGARGCNCARGAYMGNGCNTGGCCNAGYAAY GGNGCNGARCCNCCNACNGARGTNTCNYTNYTNYTNGCNTGGACNATHATHTCNYTNYTN ATHATGCCNYTNTTYTGYGTNACNGCNTTYGTNAARGTNGGNAAYYTNGCNAAYGAYGGN GTNAARYTNGGNMGNGAYCARGARGARMGNCCNTCNGTNGARAAYGAYGARTCNAARAAY GARAARCAYGARCAYATHGTNAGYAARATGMGNTAYYTNTGGAARCAYTTYTGYCCNGTN GCNCARACNYTNCAYYTNYTNGCNGCNTTYYTNYTNYTNYTNCCNGARGTNYTNYTNACN GCNCCNGAYATHTCNTGGGARAGYGARYTNGAYTTYYTNTTYCCNGCNGARMGNTCNACN YTNAGYCAYATHMGNAGYAGYGTNAAYYTNACNACNCAYCCNAAYGCNACNACNTTYGAY YTNTCNGCNACNYTNTCNGCNTCNAARGGNTGGGGNGAYMGNGTNAGYGTNAGYATHGCN TTYGTNCAYYTNTGYATHGCNYTNGTNTGYTTYYTNGTNMGNTAYGCNTCNGTNTTYTGG TAYACNAAYAARGCNYTNACNYTNATHATHGCNTTYCARYTNYTNTCNGTNGTNATHAAY TCNATHTTYGGNTTYAAYAGYTTYGCNACNYTNTAYTGYATHTGYCAYAAYCARAARYTN TTYMGNAAYATHCAYYTNTCNGTNGCNTGYAGYGTNGAYYTNACNYTNTAYYTNTTYAGY GGNGCNATHYTNYTNYTNTCNACNATHACNYTNTTYGARTAYGGNTCNCAYTAYTTYCAY GARAARTCNAARATHATHGARMGNAAYCAYGCNACNGAYACNTTYATGMGNMGNACNGTN ATHGTNAAYAGYGGNTGYCARGGNTTYATHCCNCAYTCNTGYGCNATGGGNGCNYTNGTN YTNTAYGTNATHTTYAARGGNCCNYTNATHTAYGAYATGATHCAYYTNATGMGNGTNACN AGYGAYCARYTNATGYTNTCNTCNGTNATHTGYGARGTNTGYTAYATGGTNACNTGGGTN ACNYTNTGGTTYGGNYTNACNATHAARCARAARTGGMGNTTYMGNATHYTNGAYTAYGTN ACNYTNMGNAGYACNGCNMGNGCNCARACNAGYGTNAAYMGNMGNTAYAGYGARCAYMGN GAYTCNTCNATHCCNATGGAYTAYMGNAAYAGYYTNMGNAAYAARTGYGGNGARTAYTAY GAYTCNCAYTCNCCNTCNACNGTNGGNGAYGTNGAYYTNCCNACNYTNATGTCNTCNTTY MGNGAYMGNGTNMGNGARTCNTCNYTNGCNGCNAGYAAYTTYAARGARAAYGARMGNCAR ATHYTNGARCAYTAYCAYACNTAYTCNGAYGCNGCNTCNAARMGNYTNTCNACNCCNTTY TTYGAYGTNCCNGGNGARAARYTNGCNMGNAAYYTNYTNGGNCARCAYYTNGTNMGNGCN GTNGGNACNCARCARATHAARGGNAARATHGTNGARACNGARGCNTAYYTNGGNGCNGAY GAYAARGCNGCNCAYAGYTAYAARGGNAARMGNACNCCNMGNAAYGARGCNATGTTYAAR CCNGCNGGNACNTCNTAYGTNTAYAAYATHTAYGGNATGTAYTGYTGYYTNAAYATHTCN AGYCARGGNGAYGGNGCNGCNGTNYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYATHTGYTAYTAYACNAAYTGGGCN CARTAYMGNCCNGGNGGNGGNAARTAYGTNCCNAGYGAYATHGAYGCNTCNYTNTGYACN CAYTTYCAYTAYGCNTTYGCNAARTTYAAYTCNAAYCAYACNATHGCNGCNTAYGARTGG AAYGAYGARAGYACNCCNTGGATGGTNGGNATGTTYGTNAARTTYAAYAAYYTNAARAAR ACNCAYCCNACNYTNAARACNATGYTNACNGTNGGNGGNTGGAAYYTNGGNTCNGGNCCN TTYTCNAGYATGGTNTCNACNTCNGCNAAYMGNCARGTNTTYATHCAYAGYGCNATHGCN TTYGTNMGNAARTGGAAYTTYGAYGGNYTNGAYATHGAYTGGGARTAYCCNGGNGCNMGN GGNAGYCCNGCNGGNGAYMGNGARAARTTYACNYTNYTNGTNCARGARACNATGGCNGCN TTYAARGARGARGCNGARMGNACNAAYAARCCNMGNYTNYTNYTNTCNGCNGCNGTNGCN GCNGGNAARGAYGTNATHGAYGCNGCNTAYGARGTNGAYAARGTNGCNCARGCNYTNGAY TAYATHATGYTNATGTCNTAYGAYTAYTTYGGNGCNTGGAAYCCNTAYACNGGNYTNGTN AGYCCNYTNTAYCCNCCNAARGGNGCNACN---GGNATHGAYAARATHTTYAAYGTNCAR TAYTCNGTNAAYTAYTGGGTNACNAARGGNTGYCCNAARAAYAARYTNGTNGTNGGNGTN ATHTCNTAYGGNMGNTCNTTYACNYTNACNAAYACNTCNAAYACNGGNYTNAARGCNCCN ACNAAYGGNGCNGGNTCNGCNGGNACNTAYACNMGNGARGCNGGNTTYYTNGCNTAYTAY GARGTNTGYAARATGATHCARAARGGNGCNAARATHGTNMGNYTNGGNGAYGARAARGTN CCNTAYYTNGTNYTNGGNAAYCARTGGGTNACNTAYGARGAYCARACNAGYYTNGCNATH AARGCNGAYTAYATHAAYTCNGGNGGNTTYGCNGGNGCNGGNATHTGGACNTCNGCNYTN GAYGAYTTYAARGGNACNTTYTGYGGNCARGGNCCNTAYCCNATGATGAARGTNTTYTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AGYCCNATGAAR GARTGYGGNTAY------------------------------------------------ ---------------------ATGGTNGGNAARTGGCAYYTNGGNTTYTAYAARGARAAR TAYYTNCCNAARMGNGGNTTYGARAAYTAYTAYGAYCAYAARMGNGGNTGYCAYAARYTN TAYCCNYTNCARGTNCCNAGYAARTAYACNAARGCNGGNATGGTNTCNGCNATGGAYGAR GGNGTNAAYAAYYTNACNMGNGCNYTNATGGAYACNGGNYTNTGGGAYAAYACNGTNTTY GTNTTYTCNACNGAYAAYGGNGGNCARATHYTNGAYGGNGGNAAYAAYTAYCCNYTNMGN GGNTGGAARGCNTCNYTNTGGGARGGNGGNTTYCAYGGNGTNGGNTTYGTNACNGGNCCN YTNGTNAARAAYMGNGGNACNGTNAAYAARGARYTNATHCAYGTNTCNGAYTGGTAYCCN ACNYTNGTNAARYTNGCNGGNGGNAGYYTNAAYGGNACNAARCCNYTNGAYGGNTAYGAY CARTGGGAYACNATHAGYTCNGGNACNCCNAGYAARMGNAARGTNYTNYTNCAYAAYATH GAYATHYTNTTYAARAARAARGGNGTNMGNATGTAYAARGAYACNTTYGAYACNMGNATH MGNGCNGCNGTNMGNGTNGGNGAYATGAARYTNATHACNGGNGAYCCNGGNAAYGGNTCN TGGATHYTNCCNCCNCAYTTYCARCCNGARTAYCARGARGCNGAYCARAARAAYGTNTGG YTNTTYAAYATHACNGCNGAYCCNAAYGARCAYAAYGAYYTNTCNGAYAGYAAYCCNGAY GCNGTNAARGARYTNYTNACNTAYYTNGARGCNTTYAGYAARACNGCNGTNCCNCCNMGN TAYCCNAARAAYGAYMGNAARAGYAAYCCNGCNYTNCAYGGNAAYGTNTGGGGNCCNTGG ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AAYAAYATHATHGTNAAYGAYATH GARCARCCNGTNYTNGCNACNGTNCCNGAYGAYGAYTTYGTNTAYGARAARGGNMGNAAY YTNACNATHACNYTNATHCARCCNMGNGGNAGYTTYYTNTCNCAYGARACNACNAGYAAR GARYTNGTNATHYTNGAY------------ACNAARAAYAARAAYGGNATHAAYTCNACN GAYTGGAGYYTNAGYTCNGTNYTNGARGARACNAARTTYYTNGARGARAARGARACNCAR ATHGARYTNAAYACNGCNGCNATHACNTTYTCNGGNYTNYTNATGATHTCNTCNGCNMGN AAYGARAAYTCNGAYYTNATHATGMGNATHGARMGNGARATGATHGTNATHGTNMGNCCN TTYACNCARMGNGGNCCNTTYCCNMGNGGNAARYTNGCNATHMGNAAYTCNCCNCCNGAR TCNMGNYTNGTNGAYAARGAYYTNTAYYTNAAYGARTAYTGYGGNGARGCNTGYCAYGTN GAYTGYAGYTTYTTYGGNATHGAYATHAARMGNGTNAARATGTTYAAR---ATHAAYGGN ATHTCNCAYMGNGTNCCNTCNAARGAYAAYAGYGTNGAYCARACNTAYAARCARATHTGG CAYYTNTTYACNCCNAARCAYAAYGAYATHTTYCCNTTYAAYATHTCNTGYGTNGCNATG AAYAARAAYAARGTNAARMGNGTNATHAAYACNCARATHAAYMGNATHGAYGARGTNAAR ATHATHGARGARTCNTCNGAYGCNAARAGYYTNGGNAAYGGNACNGTNGARGCNGTNTGY ACNGCNCARGGNATGCCNMGNCCNTCNGTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GCNGARTAYYTNAARGTNAARCCNGCNYTNGCNAARGARATHATGCAYAAY TTYYTNGCNMGNTTYCCNGCNATHGARAARTTYACNAARAARTGYTGYGCNTAYGCNAAR GARTAYGGNTAYACNGARACNATHTGYGGNMGNMGNMGNTAYTTYCCNTAYATHAAYAGY ACNTCNCCNGCNYTNMGNTCNCARGCNCARMGNCARGCNGTNAAYTTYTGYGTNCARGGN TCNGCNGCNGAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHGAYMGNYTNAARMGNATHACNCARGGNTGYAARMGNYTN TCNTCNGTNGAYGGNMGNGCNGCNTCNYTNGARYTNYTNGARCCNCCNCCNCCNGCNCCN CCNATGGCNMGNTGGTCNGGNGARATHACNGCNATHCCNATGGTNGARGCNGAYGCNTCN MGNAGYGAYATHGAYCCNGAYATGYTNGCNGCNYTNGARACNGTNATGGAYGARYTNGTN GAYGARGTNACNYTNGGNYTNTGYTTYGARATHGAYMGNTCNTGYAARATHGGNTTYTTY YTNYTNGAYGCNGGNGAYGAYGCNTCNGARACNGARTAYGCNGTNATHGARMGNCCNGGN GTNGAYGTNYTNGGNCARATHCCNTCNAARAARAAYTTYGARTGYGTNTGYCCNAAYTGY CARMGNCAYYTNGCNGCNTCNMGNTTYGCNCCNCAYYTNGARAARTGYATGGGNATGGGN MGNAAYTCNTCNMGNATHGCNAGYMGNMGNATHGCNAAYAAYCARAARCAYGGNAGYGAY GARAGYGGNCARGAYGAYGARAAYGAYAAYGAYTGGAAYTAYGCNCCNGAYTCNAARMGN YTNMGNAARYTNAARAARGAYAARATGTCNGGNTCNCCNMGNAAYMGNMGNYTNGCNAAR YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNTGYTAY ATHTCNMGNAAYATHTAYATHAARAARTAYMGNYTNCAYGCNGCNTTYAGYGAYGARGAY CARTTYTAYCARGAYTTYMGNCARATHYTNMGNATGAARGGNTGYTCNACNGARAARCAR TAYCARGAYGTNYTNCARGARATHAARAAYGARGTNTGYMGNMGNMGNAGYTAYCAYMGN GAYGCNGARGAYMGNMGNYTNYTNATHTCNAAYACNTAYAARCCNYTNCAYTCNAAYATH TGGCAYTTYGAYAAYYTNTTYGTNGAYGARMGNYTNMGNAARATGGCNGGNTCNATH--- CARAGYMGNAAYMGNGAYGARGCNCARGARGTNATHGTNCARAAYAAYGGNGARATHYTN GGNGAYTAYYTNTAYMGNATHCCNGTNTTYTCNCCNGCNTTYTGYGARAARYTNGTNGAR GARYTNCARAAYTTYGARGAYAGYTCNAGYCCNAARGGNMGNCCNAAYACNATGTCNCAY TAYGGNGTNTCNYTNGAYGARATGGGNYTNTCNCCNAGYYTNYTNACNCCNYTNATGGAR ATHTAYATHCARCCNYTNACNGAYGCNYTNTTYTGYAARTGGTGYCCNGARAARYTNGAY TCNTTYMGNGCNTTYTCNGTNYTNTAYAGYAGYGAYAARGAYAARGARYTNAGYYTNCAY TAYGAYAAYGCNGARATHACNYTNAAYGTNTGYYTNACNTCNCARTTYGAYGGNGGNGAR YTNGARTTY---MGNCARTTYTGGGAYGARCCNGAYATGGARYTNCARAAYMGN------ ---GTNGTNCARCAYAARATHGGNACNGGNATHYTNCAYYTNGGNMGNCAYATGCAYCAR GCNTTYCCNATHAARGGNGGNACNMGNTGYAAYYTNATHATHTGGATGMGNAGYTCNAAR GTNMGNAAYAARYTNTGYGTNATGTGYGGNTCNAARCCNGAYYTNCARCCNGTNCCNTTY GCNGGNGAYGGNTTYACN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATHGARAARACNTGGGAY AAYAARCCNATHAAYCAYGAYCCNGTNAARATHGCNYTNAGYGAYGAYAARTGYGGNAAY YTNAARYTNAAYGTNAARGCNCCNTTYTTYAAYAGYCCNGCNAARCCNGAYGGNCCNCCN GGNCARCCNTTYCCNCARYTNTGGGAYTAYGARGTNGTNGARGCNTTYTTYYTNAAYGAY AAYGAYCARTAYYTNGARGTNGARYTNAGYCCNCAYGGNCARCAYYTNGTNYTNATGYTN AAYGGNMGNMGNAARATGATHAARCARYTNYTNCCNYTNACNTTYACNCCNTCNATHAAY GGNGAYATHTGGACNGGNGARGCNATHATHCCNYTNGGNTAYYTNCCNTCNGCNGTNACN AARTTYAAYGCNTAYGCNATHCAYGGNGARGGNCCNGAYMGNCARTAYGARTCNYTNTAY CCNGTN---------AAR---------GAYGGNATGGARCCNGAYTTYCAYMGNYTNGAR CARTTYAARTCNYTNGAYATGAGYTCNATHATHAGYGAYTAYGAYTCNACNAARGTNTCN AGYATHTGGAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARCCNMGNYTN GGNGARGGNGCNTTYYTNGCNTCNGARCAYATHYTNMGNGGNTCNAARCCNACNAARAAR GGNTCNAARGGNGCNAARTCNGGNTAYMGNAGYMGNCARACNGGNGARGGNGCNAGYAAY TCNGGNATHGAYCARGCNAGYGARAGYTCNATGTCNGAYATGCCNTAYCCNMGNATHGAY ATGAARCARYTNGAYCAYCARATHAARCARGTNATGATGGARACNATHCCNGTNGTNAAR GAYCAYATGGARGAYATHTGYTCNAGYCARYTNYTNGCNTAYATHAARMGNYTNGTNYTN TCNYTNACNGCNCARACNGGNTCNCARGARTTYGCNMGNTTYTTYCAYMGNCARYTNTCN TCNATHYTNCARGAYACNYTNGARAARTAYGARGGNMGNAARATGMGNGARTGYGGNGAR GAYYTNYTNGTNGARATHTCNGAYYTNYTNTTYAAYGARYTNGCNTTYTTYMGNYTNATG CARGAYATHGARGAYCCNAAYGARGTNGARMGNYTNMGNGCNGCNGCNCARTCNTAYCAR GGNMGNMGNCAYYTNGAYGARMGNGARGAYAAYGARGAYAGYAGYTTYAAYGARGAYGGN GAYGTNGAR--------------------------------------------------- ---------------------------------------------------AARACNTTY ACNATGYTNGGNCCNTCNGARAAYGCNGAYAGYTTYCARCAYGARYTNMGNGGNGTNATH CCNMGNGGNTTYGARTAYYTNTTYAGYYTNATHGCNCAYCARCARGARYTNCAYGGNAAY AARMGNCARTTYYTNTGYMGNTGYTCNTTYYTNGARATHTAYCARGARCARATHTTYGAY YTNYTNGAYCCNACNTCNCARGGNYTNCAYYTNMGNGARAAYATHAAYAARGGNGTNTTY GTNGAYGGNYTNATHGARCARGTNACNTGYAGYCCNAGYGAYGCNTAYCARGTNYTNATH ATGGGNTGGYTNAAYMGNMGNGTNGCNGCNACNTCNATGAAYMGNGARAGYTCNMGNTCN CAYGCNGTNTTYACNGTNACNATHGARTCNAARGARGARGTNGAYGGNGTNCARAAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AAYACNCCNACNCAYCCNGTNGTNAGYTCNCCNMGN CARTTYYTNMGNACNCCNCCNYTNAGYCCNACNCAYTTYATHGCNTCNGCNGTNCCNTCN TCNCCNTCNTCNTAYCCNTCNGTNGAYGCNCARCAYTCNCCNATHCCNAAYTCNCCNTCN AAYAGYAAYGGNCCN---TTYAGYGTNGARTTYCARGTNTCNGARCARGAYYTNGCNYTN ACNACNATHCCNGAYTAYGARGAYTCNMGNGTNTAYGCNAARGAYCARGARTGGATHAAR ---------------------------------MGNGTNAGYTTYGAYCCNMGNAARMGN AAYTTYTCNGAYGARGARYTNAARCCNCARCCNATHATHAARAARTCNMGNAARATHTTY GTNCCNGARGAYYTNAARGAYGAYMGNTAYTGGGCNMGNMGNACNAARAAYAAYTTYGCN GCNAARMGNTCNMGNGAYGCNMGNMGNGTNAARGARAAYCARATHGCNYTNMGNGCNTCN TAYYTNGARAARGARAAYAARTGYYTNAARGAYGARATGACNAARYTNCARAARGARAAY GCNAARYTNAARATGATHGCNGARAARTAYGARCCNACNGCN---GTNTCNCCNAGYTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTNAARGCNATGGAYATHTCN YTNMGNGAYYTNGTNGGNGAYGTNCCNTCNAGYAAYCAYTTYGTNACNYTNGGNGAR--- ------AARCAYACNATHACNCCNTTYAGYAAR------MGNMGNCCNCAYACNTCNTAY GTN---MGNCAYGCNCCNAAYACNTAYAAYGAYGCNGCNMGNTAYAAYAARGGNGAYATG TTYGAYGTNMGNGARACNGAYGTNATHMGNAARCCNMGNCCNGTNAGYGCNTCNTCNYTN MGNGAYGCNGAYGCNGCNMGNTCNMGNCCNMGNTCNGGNTCNATHGGNAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARAAYTAY YTNGARTCNGTNAARCCNYTNGTNTCNGARGARGARTTYATGCARACNGARTTYYTNTGY CARCARTTYGCNACNGGNGAYGGNCARMGNYTNCARGARGCNYTNMGNCARAARGCNGTN GGNGARMGNAAYTGGYTNGARCARTGGTGGGAYGAYYTNGCNTAYYTNGAYTAYMGNATG GCNYTNCCNYTNATHAAYATGGGNGGNCCNGGNCCNTAYTCNGARGAYATHTGGCCNCCN GARGARGGNACNCARYTNTAYMGNGGNGCNYTNACNGCNTAYTAYACNYTNAARATGTGG YTNTTYGTNAAYMGNGARCARTAYATGCCNATGAARGAYCAYAARGGNMGNCCNATGTGY ATGTAYCARTTYMGNMGNATHTTYAAYGGNGGNMGNATHCCNGGNGTNAAYMGNGAYAAR YTNGTNAAYCAYTTYAARACNGARTCNGARGGNGARTGYCCNTCNCAYATHATHGTNGCN TGYAARGGNCAYTTYTTYGTNATGAAYGTNYTNGAYGARGCNGGNGARATHATHACNCCN ATGGARATHGARATGCARTTYATHMGNGTNAARACNGARGCNAARMGNYTNGGNCCNGCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CAYAAYCARYTNGARAARAAYMGNMGNAARCARATGMGNGARTGYTTYAAYTAYYTNCAR CARTGYATHCCNGCNATGYTNACNATGAARGAYACNACNTGYGAYGAYTCNGGNATHTAY ATHTGYMGNATHGTNCAYGTNATHTCNGCNGGNGTNACNCARGARAARTCNCARCCNYTN AAYGGNACNGCNATHGCNTCNATGGTNGARATGACNTTYAGYYTNGGNMGNCARGARGTN TCNTAYAARGARAAYACNTCNGTNACNYTNACNTGYAAYGGNGAYGCNYTNGAYGAYTAY CARTAYACNTGGMGNMGNAARTGYCCNGCNAGYCARTTYTCNTCNTCNMGNTGGGARATH TGGCCNACNTTYAAYGAYATHTCNCCNYTNGTNGAYGGNAAYGGNTAYCCNGAYCARTGY GGNYTNYTNMGNCAYAGYCARMGNYTNACNTTYYTNATGACNGARAAYYTNGAYAAYTGY ATGATHAARTGY------------ACNYTNGCNYTNGGNGGNCARGAYCCNCARGARGCN AAYATHACNGTNGTNGGNGGNAAYGGNAAYATHGAYCCNGGNAAYACNGGNGGNTCNGTN AGYTCNGCNAGYGGNGAYGAYYTNGCNATHGGNYTNACNGTNTCNYTNYTNYTNGTNGTN ATHATH------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARGAYATHGTNATHYTNACNTGYGGNGGNACNATHGAYAARCARTAYCCN CARGGNCCNGGNGCNTAYGCNTTYGARTTYGGNGAYGCNGCNGTNAGYAARATHYTNCAR MGNGTNGGNATGGCNACNCCNTAYACNATHGARACNATHTGYGCNAARGAYAGYCARGAY ATGAAYGAYTCNGAYMGNGARTCNATHYTNAAYMGNGTNACNGARMGNGARCARTCNYTN TTYYTNATHACNCAYGGNACNGAYACNYTNTGYGAYACNGCNCARTTYYTNATHAARGCN GGNGTNGGNMGNGGNGAY------TCNTCNGARAAYGGNMGNAARACNGTNGTNYTNACN GGNGCNTTYAARCCNGARGCNATGAARGAYTCNGAYTCNGAYTTYAAYATHGGNTTYGCN YTNGGNATHYTNCARTGYTCNTCN---CCNGGNGTNTTYATHGCNATGGARGGNAARYTN ACNGAYGGNGCNTAYGTNACNMGNAAYAARCARGGNMGNTTYGTNGAYTCNMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CARYTNTCNTTYCARGTNATGGTNYTNATGGTNGCNAARCCNTTYCCNAARTTY YTNAARGAYATHGTNATHCCNTTYYTNAARMGNYTNTGGGCNMGNMGNCCNAAYTGYMGN TGYTTYAAYAARAAYAAYCARATHGARGARYTNGAYAARACNAAYGCNGARAAYGTNCAY CAYAARAAYCAYAARTCNTTYYTNGARMGNGARMGNGCNAARCCNGAYYTNGARGAYTTY ACNYTNGCNGARTAYACNGARAARGTNATHYTNTAYGGNTTYYTNATGYTNTTYGCNTGY TCNTTYCCNYTNGCNCCNYTNYTNGCNYTNGTNATHTGYTAYATHGAYATHAARGTNGAY GCNAARMGNATGYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATGATHCCNCAYTAYTTYAARAARGAYTCNMGNGTNTGG YTNCAYAARAAYTCNAARMGNGCNGARACNGARTTYACNMGNGARTAYGGNAAYGAYTGY TAYMGNCARCARACNGGNTAY------ACNATGGARGAYGARGGNTGGGAYCAYACNCCN TAYATHACNGGNGCNGAYGGNAARGCNTAYAARAARGAYAGYMGNACNTGGYTNCAYAAR GCNTCNGAYAARATGYTNTCNMGNTCNGGNMGNGCNGARACNMGNAGYMGNGCNAARGAR GAYATHAARMGNGTNATHAAYGCNATHGAYAARGTNMGNAARTGGGARAARAARTGGGTN ACNYTNGGNGAYACNTCNGTNACNATHYTNAARTGGGTNCCNGTNACNGCNCARGARAAY CCNGGNGCNYTNMGNAARATHCCNGGNGTNAARACNAARACNTAYTCNAARGCNMGNGTN GARMGNGARMGNGARYTNTAYAAYGCNGARACNAAYTCNAAYCCNMGNGCNAAYTCNCCN GCNGAYTCNCCN------CCNACNAAYYTNTCNAAYACNAGYTCNCCNTCNTCNAARACN GTNAGYTCN------GAYAARGCNMGNAAYGGNGTNGTNAARAAYTCNCARGGNTCNGTN ATHTAYACNGARGARAAYACNCARCARTCNGTNGGNTCNTTYGGNTCNGARAAYYTNAAY GARGAYTCNAAYATGTCNTTYCCNGARAAYAGYGARYTNAGYGARCAYGCNGARAAYAAY GARTTYTCNCAYGAYAGYAAYGAYGCNGAYCCNGGNATGMGNGTNGCNATGAGYATGATH GGNGAYGARGAR------------------------------------------------ ------------------------------------------------------------ ATGTCNGARAARCAYAGYTTYGGNGTNGCNCCNGTNACNTGYCAYGCNTTYAAYAARGAY MGNAAYGGNYTNGCNATGTCNYTNAAYGAYTCNGAYGTNAARGTNTAYAARAARTCNGGN ACNMGNTGGGARGARTCNGAYACNYTNAGYGARCAYGGNCARMGNGTNACNAGYATHGAY TGGGCNCCNAAYAGYAAYMGNATHGTNACNTGYTCNGCNGAYMGNAAYGCNTTYGTNTGG ATGYTNGARGGNGGNAARTGGAARCARGTNYTNGTNATHCCNMGNATHAAYMGNGCNGCN ACNTGYGTNAARTGGTCNCCNAARGARAAYAARTTYGCNGTNGGNAGYGGNTCNMGNYTN ATHGCNATHTGYTAYTAYGAYGTNGARAAYAAYTGGTGGGTNAGYMGNCAYATHAARAAR CCNATHMGNTCNACNGTNACNTGYYTNGAYTGGCAYCCNAAYAAYGTNYTNYTNGCNGCN GGNTCNACNGAYTTYAARTGYMGNGTNTTYTCNGCNTAYCARAARGARGTNGAYGARAAR CCNGGNCCNTGYTCNTGGGGNACNAARATGCCNTTYGGNGCNYTNATGGCNGARTTYAGY AAYGGNGGNGGNGGNTGGGTNCAYTCNGTNAAYTTYTCNCCNAGYGGNACNYTNGTNGCN TGGGTNGGNCAYGAYTCNAGYGTNTCNGTNGTNGAYTCNTCNAAYGGNAAYATHYTNACN ATGATHAARGAYAGYTTYYTNCCNTTYATGAGYATHACNTGGGTNACNGARAAYTCNYTN GTNGCNGCNGGNTAYGAYTGYAAYCCNATGGTNTTYTCNTAYGCNGGNGGNAGYATHACN TCNCARGGNAARYTNGAYGTNCCNCARCARAARGARTCNGGNGCNATGAGYGCNATGAAY MGNTTYAARAAYYTNGAYMGNAARGCNACNGAYAGYGAYAGYTCNCCNGARATGAARACN CARCAYCARAAYACNATHACNCARGTNTCNATHCAYACNGGNGAYAARACNGAYGCNAGY AARATHGCNACNACNGGNGTNGAYGGNAAYYTNATHATHTGGGAYYTNAARYTNGAYAAY GCNAGYCAYMGNCCNGCNGGNGGNGAYAARAARATHGARTCNAARAARYTNGAYTGGAAR GTNGAYTCNAARATHGGNTCNYTNGAYAAYGCNAAYCAYGTNGCNGGNGGNGGNGAYAAR AARATHGARCARGTNAARACNGAYTGGAAYGCNAARTCNAARATHGGNTCNYTNGAYAAY GCNACNCAYAARCCNGGNGGNGGNGAYATHAARATHGARAAYCARAARACNGARTGGAAY GTNACNTCNMGNATHGGNTCNYTNGAYAARGCNAAYCAYAARCCNGGNGGNGGNGAYGTN AARATHGARATHCARAARACNGAYTGGAAYGCNCARTCNAARATHGGNTCNATGGAYAAY GTNAARCAYMGNCCNGGNGGNGGNGAYAAR---------------------CCNGGNATH TCNTTYTTYTTYAAYCCNYTNTCNGCNGGNTAYMGNMGNATHTGYTGYGARTGYATHATG CCNYTNYTNGGNYTNCCNYTNTTYMGNGAYGCNAARACNTCNTGYGTNTTYTTYGGNGTN YTNGTNYTNTGYTAYTAYGTNATHATGGAYATHATHYTNTTYATGMGNTTYMGNAGYACN AAYATHGTNGARGAYTCNAARCCNGGNGCNGCNGAYGARYTNTAYTCNCCNTTYACNCAY YTNTCNATHAARGCNYTNATGAAYGAYCAYACNAGYCARTAYATHATH------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNAARYTNATHGTNTTYGAYYTNGAYTAYACNYTNTGGCCN TTYTGGGTNGAYACNCAYGTNGAYCCNCCNTTYAARGTNGGNAARAAYAGYAARATHTAY GAYMGNMGNAAYTAYGARGTNAARCAYTAYGCNGAYGTNCCNCARATHYTNTCNAGYYTN CAYGARCARGGNATHAARYTNGGNATHGCNTCNMGNACNGGNGCNAGYGCNGARGCNAAY GAYYTNGTNMGNYTNTTYGAYTGGGAYAARTAYTTYCAYTAYMGNCARATHTAYCCNGGN TGYAARATHCCNCAYTTYAARAARYTNAARATHYTNAGYGGNYTNCCNTTYGARGAYATG YTNTTYTTYGAYGAYGARCAYMGNAAYATHGCNGAYGTNTCNTCNYTNGGNGTNACNTGY ATGTTYGTNGARGAY---GGNGTNACNAARGAYTGYTTYGCNAARGGNYTNGARYTNTTY ---MGNAAYAAYCCNAARCAYGGNACNTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TTYATGAAYGAYTCNGGNACNAGYTCNATHAAYAGYTCNAARYTNGAYGCNGTNGCN GAYYTNYTNAARAGYCCNTCNMGNCAYYTNGTNTCNCARTAYGTNAARGAYMGNGCNGAR TAYMGNATHGARMGNCARGARMGNGCNGARAAYGAYMGNGARMGNMGNYTNCARGARCAR CARATGAGYTCNAGYGARGAYGARATHCARGARMGNTAYGCNGARYTNYTNGCNATGAAR GARGAYGARMGNGCNMGNMGNMGNGCNYTNAARAARAARAARGGNAARAARGGNYTNTTY TCNATHCCNGARGAYMGNAGYAAYGAYCCNTCNCCNTGYAARTCNCAYACNCCNTCNAAR TCNAARAARCCNCAYGCNACNMGNCARTCNAAYGTNATHGAYCCNAGYATGGTNAARYTN MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARTGGTGYGGNGCNAARAAYTGY AARAAYTCNAARGTNAARTAYCCNCARYTNGCNTTYTTYTCNTTYCCNYTNGAYCCNGCN MGNTGYACNAARTGGGTNATHAAYTCNGGNMGNACNGAYYTNYTNGARCARTCNCCNCAR AARYTNAAYMGNGGNACNGTNGTNTGYGARATHCAYTTYGARAAYTGYTGYTTYAARGAR ACNMGNGGNAAR---MGNAARYTNYTNMGNAAYGAYGCNGTNCCNACNYTNTTYGAY--- TGGTTYCAYTGYAAYGGNTGYTAYTGYCARCCNGARTCNGGNACNYTNMGNTTYTTYATH ACNAAYTGYAGYCAYATHTAYTGYGARAARTGYGTNACNGARTGYACNAARGARCAYTGY AARYTNTGYAARTCNCARTGYGCNGTNYTNGARATHGGNACNAARATGCARAARGARGTN GARACNYTNTTYGARGARCCNTCNGCNATGYTNCARAARTGYTTYAARAARATGAAYCAR ACNATHGARTTYCARAGYAGYCAYCARMGNMGNTGGTCNMGNCAYYTNAARGARGTNYTN MGNCARCARACNAGYCARYTNAARGAYGTNAARAARYTNGTNACNCARTTYMGNTGYYTN GARAARGARYTNATGGARGTNMGNAARGARAAYAGYTAYYTNAARTGYYTNYTNGCNAAR AAYACNMGNTAYATGACNCCNGGNAGYGCNGGNAGYGTNGAYATGGGNAAYMGNTCNTGY ACNCCNYTNTCNGTNCCNMGNCCNATHTAYYTN---GCNAAY---ACNATGATHGTNTAY AARTGYATHATHTCNGGNGAYGARATHTTYAAYGAYAGYTTYAAYTTYAARGARGARGGN GGNTTYTAYGTNYTNAARGCNAARTAYATHACNGTNAAR---CARGAYGAYGTNGAYGAY TCNGCNATHGGNGGNAAYCCNAGYGCNGARGARGARGCNGAR---GGNACNGARGGNGCN ACNGARTCNGGNYTNGAYGTNGCNYTNGCNAGYMGNYTNGTNGARACNGGNTTYGGNTCN AARAARGARTAYCARGTNTAYATGAARGAYTAYACNAARGCNATHTTYGGNAARYTNACN GARAARYTNTCNACNGAYGAYTTYGAYGCNYTNAARAARGCNCAYGGNGCNGGNTTYYTN GARATGTCNAARAARTTYAARGARYTNTCNTTYTAYACNGGNGARAGYATGAAYGTNGGN GGNATHATHCCNYTNGTNGAYTGGGTNGAYGARGARATHGAYGGNCARACNCARAAYGTN CCNTAYTTYTAYTGYTAYAARGCNGGNYTNGTNGCNGARAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNCCNMGNCARGTNMGNGARTTYGAYGCNGTNGARAGYTCNGAYGAYGAY GAYAARGAYCCNGAYGGNAAYGTNTCNGAYGARGAYACNGCNGAYGCNAGYGARACNGAR GARAARACNCCNAARGTNTCNAARCARGGNCCNCCNAGY---GGNAAYCARMGNACNGAR ATHAARGARCARATGTAYCARGAYAARYTNGCNCARATHAARAARCAYATHAARATGYTN GARGARGGNACNYTNCARGARTTYYTNAARMGNACNAARAARATHGARYTNAAYTAYMGN GARMGNYTNMGNGAYAAYGARATHTGYAARAARGTNGAYATHGARAARGCNGARCARAAY TAYCAYGTNGAYTGYGARAAYTCNCARAARGARTTYGARGARAARGGNGARGCNYTNAAR GAYAAYYTNATHAGYMGNYTNAARGARAARAARATHGAYYTNAARGARACNYTNATHAGY GAYCARAARGARAARMGNAGYATGATHGARYTNGARMGNCARACNGTNGAYATHAAYGGN GCNGAYTTYATGGARGTNAARCCNACNATGACNMGNAARYTNMGNMGNMGNCCNAAYGAY CCNATHCCNATHCCNGARAARMGNMGNAARCCNTCNCCNGCNCARGTNAAYATHYTNYTN GAYGAYGAYATGATHYTNGAYGAYYTNMGNGTNATHATGAARGTNAGYGGNAARCCNGTN GCNAARAARCARGGNYTNGGNAGYCARAGYCCNYTNGTNGAYCAYTCNTCNGAYGTNMGN ATHGARGAYGGNMGNYTNTGGTAYGAYAARAARTGGTTYCARMGNAAYAGYATGGTNCAR ATHGAYAAYAARGARAGYGGNATHMGNATHTGYGGNACNATHACNAAYATHYTNAAYAAY GARATHTGGGTNAARAARAGYGGNGAYAAYTCNAARYTNMGNATHTGYGTNTCNCARTTY CARAARGGNAARTAYAAYATGAARAARMGNACNACN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GARATHAARCARCAYCAYAARTCNGAYTCN ACNTTYGTNGARAARYTNYTNYTNGCNMGNAARCARYTNATGGGNYTNGTNCCNACNATH CAYMGNATGGARGCNGTNATHGTNGTNGARGARATGTCNMGNGCN---GCNCCNAARGCN MGNGGNGCNGAYAARACNAARCCNCCNGCNTCNCARACNCCNGTNATHACNCAYGARATH GTNCCNGGNAARTTYAAYGAYAAYGAYTGGAAYGTNATGYTNGARMGNGAYGGNGGNGAR GARTAYGTNYTNGAYATHGTNGAYGARYTNATGGAYMGNACNATGGCNACNATHTAYGAY AARTAYATHGARMGNCARYTNYTNCCNTTYACNATHACNCARGCNMGNGAYGCNATHATH GARATHATHGARTGGCARTTYYTNGCNMGNGAYGARGGNGARGAYAAYACNTCNACNGAY YTNGGNTGGATHCARGAYGARGARCCNGARCCNGCNGARACNGAYTGYTGGGCNCARGGN TCNGTNCCNMGNAAYYTNGTNYTNGCNCCNACNCCNGARYTNGARGARATHCCNGARGAR ACNGARGARATHTCNCAR---------------GARGCNGARGARATHACNGCNGCNGAY GARAGYGCNCARCARGARCCNGCNGARYTNGARGAYATHGTNTCNGARCCNGAYGARACN CCNGARATH------------GTNGTNTCNACNGARGARATGGARATHAARGTNCCNATH CCNCCNGCNCARACNAARGCNTCNAARACNAARTTYAARCCNTAYMGNGGNAARYTNAAR TCNGCNGGNGTNAGYAARATGACNGARTCNYTNGARGARAGYGARATGAARATGATHTAY AAYGARATHGTNGCNTCNYTNCCNCCNAAYGAYGARAARCCNAAYACNYTNYTNAAYATG CCNGCNTCNTGYACNAGYATHYTNAARGTNCARACNGGNMGNCCNCCNGGNAAYAARGAY GTNYTNTAYGAYGARATGGGNAAYGTNGTNGCNGTNATGAARYTNGAYCCNGARAARYTN CCNACNCAYAARGTNAGYGTNAARTAYCAYGTNGTNGAYCCNGCNGTNGARGCNGCNCAR GCNMGNYTNGAYGCNATGMGNAARGGNAARTCNACNGGNAGYMGNATHMGNAARGTNAAR ACNACNAARAGYATHTCNGTNGCNAAYGCNGGNGTNACNGCNAARAGYAARGTNACNGCN GCNGGNGCNTCNGTNGCNCCNYTNCCNCCNCCNYTNGCNCARGAYGGNGAYACNYTNGCN AARCARGAYATGCCNGARMGN---AGYMGNMGNATHGARGARATGGARGTNGCNAAYGGN GTNATHATHMGNGARGGNGGNMGNACNAARAARGGNCCNGGNMGNTAYTAYMGNAARYTN GAYATHYTNGARGAYCAYCARAARGGNATGAARCCNGTNGCNGTNMGNYTNACNAAYGCN GGNATHACNGTNAAYGAYATHYTNGAYMGNAAYACNCCNATHYTNMGNCCNYTNACNGAY ACNGCNCCNYTNCCNCCNATHATGCCNCARCCNCCNCAYCCNMGNCAR---CAR------ ATGYTNMGNGTNGGNGTNATHGGNGCNGGNGTNATGGGNYTNAGYTCNGCNATHAAYGTN YTNAAYYTNATHCCNAAYTCNTCNGTNACNATHATHGCNGAYCARTTYGGNCCNGARACN GTNAGYTAYGGNGCNGGNGGNYTNTTYMGN---------CCNGAYYTNAAYACNYTNGTN GAYTAYGARYTNATGACNCARTGYYTNMGNGAYTCNTGGMGNCAYTAYGCNGGNYTNGCN ATGTCNGARGARTCNCARGCNAGYGGNAAYATGYTNGCNCCNGGNATHYTNGCNCAYMGN AARGAYATGGAYAARGCNTAYGCNYTNYTNMGNGARYTNTCNTTYAAYTTYMGNCARYTN ---ACNGAYMGNGARATHCARMGNATHTAYCCNGARGARTTYAARTAYGTNTAYTCNTGY ATHACNATHATHTCNCARGGNAAYMGNTAYGTNGAYTGGYTNCARAARCARTTYGTNTCN AARGGNGGNAARATHGARMGNMGNACNGTNAAYAAYATHGARGARYTNCAYGGNAARTAY GAYGTNGTNATHAAYTGYTGYGGNYTNMGNGCNAARACNTTYYTNTCNGAYCARGARTGY TTYCCNACNMGNGGNCARYTNGTNCAYYTNAARGCNCCNTGGTTYAARTTYTGYACNTAY YTNGAYACNGAYGTNTAYGTNTTYCCNCAYTTYGAYAARGTNGTNATHGGNGGNATHMGN ATHCAYCAYGAYCCNGAYACNTCNGTNAARCCNGARGTNGCNAARTCNATHYTNAARMGN GCNGARGCNATHTTYCCNCARYTNAARGGNGCNGARATHATHGGNGGNTGGGCNAAYTCN MGNCCNGGNMGNACNTCNATHMGNYTNGARACNGARATGATHAARATHGGNGAYAAYGAR ACNYTNCCNGTNGTNCAYAAYTAYGGNCAYGGNGGNAAYGGNATHACNYTNAGYTGGGGN TGYTCNATGCAYGCNGCNAARYTNGCNAARCARATHYTNACN------GAYGARGAYYTN CCNGTNCCNGGNTCNCCNCCNYTNCCNAARAARGGNAGYTAYGCNATHGAYTTYGAYAAY YTNGAYGARTTYTCNAAYCCNTTYGARTCNAARAGYAARGTNATGATGGGNTCNTCNCCN CCNATHCARTCNAAY---------------------------------------GAYCCN TTYAARTCNAARCARTCNATHGCNAAYTCNCCNCCNGGNTCNCCNMGNTCNYTNCCNAAR GCNCARCCNGARCCNGTNGTNGARGAYGAYYTNCCNYTNCCNCCNCCNCCNCCNGARYTN YTNGAR------------CCNTCNYTNACNAGYGAYACNTCNACNGARAAYGARAAR--- ---GTNATHCARAARAARAARAARATHATHAARAARCCN---GTNCARTCNAARTTYAAR CCNCCNAARAAYTTYAARAARCARAARAAYTCNGGNGAYATHGARATHGTNATGCCNAAR ACNGGNYTNTAYTGGGTNGAYATGGGNCARAGYTGGCAYCCNMGNTAYCCNMGNTAYTCN GCNAGYTTYTAYMGNACNTTYATHGCNGAYMGNGGNYTNACNAAYGCNACNATHAAYTAY MGNGCNTAYCCNGAYGAYMGNGAYGGNTTYTAYTAYGGNAARTTYCCNTCNAAYTTYYTN TGGGGNGTNGCNACNTCNGCNTAYCARATHGARGGNGGNTGGAAYGCNGAYGGNAARGGN GCNAGYATHTGGGAYACNTTYGCNCAYAAYGGNAARYTNGCNGAYGGNCARACNGGNGAY GTNGCNTGYGAYAGYTAYCAYATGTAYAARGAYGAYATHACNATGYTNAARACNYTNGGN GTNAAYTAYTAYMGNTTYTCNGTNGCNTGGAGYMGNGTNATGAGYGAYGGNACNAAYMGN GGNATHAAYCARGCNGGNGTNGARTAYTAYAAYCAYYTNATHGAYGCNYTNATHGCNGTN AAYATHACNCCNATGGTNACNYTNTAYCAYTGGGAYYTNCCNCARGCNYTNCARGAYAAR GGNGGNTGGAARAAYGAYACNATHGTNGAYYTNTTYMGNGAYTAYGCNMGNYTNTGYTTY GARCARTTYGGNGAYMGNGTNAARTAYTGGATHACNTTYAAYGARGCNTTYGTNGTNAGY TGGYTNGGNTAYGGNATHGGNGTNTTYGCNCCNGGNATHTAYGAYCCNGGNAAYGGNGTN TAYACNGTNGCNCAYAAYATHATHMGNTCNCAYAGYGCNGCNTAYCAYYTNTAYAARGAY CAYTTYAARTCNMGNTAYGAYGGNCARATHGGNATHACNYTNGAYATHGARTGGAARGAR CCNYTNACNGAYTCNCARCARGAYYTNGARGCNGCNGAYMGNGCNATHCARTTYAARYTN GGNTGGTTYGGNAAYCCNATHTAYGGNGGNACNGGNGAYTAYCCNCARGTNATGAARGAY TTYGTNGCNAARAARAGYAARGCNCAYGGNYTNYTNAARTCNMGNYTNCCNGARTTYACN GARCARGARAARMGNYTNAAYAARGGNGCNTAYGAYTTYYTNGGNATHAAYCAYTAYACN ACNAAYYTNGTNGCNGAYAAYCCNMGNCARAAYAGYGARCARAAYTAYGARCARGAYCAR GAYATHGAYACNAARGCNGAYCCNTGYTGGCCNGGNACNGARGCNAGYTGGYTNAARGTN AAYCCNTGGGGNATHMGNAAYATHGTNMGNTGGGCNMGNGAYCAYTTYGGNAAYCCNCCN ATHTTYATHACNGARAGYGGNMGNCCNGAYATHGAYTCNYTNGAYGAYCARGGNMGNATH TAYTAYTAYAARTAYTAYATHAAYGARYTNYTNAARGCNATHMGNYTNGAYGGNGTNGAY ATHMGNGGNTAYACNGCNTGGTCNYTNATGGAYAAYYTNGARTGGACNAGYGGNTAYTAY GCNAARTTYGGNYTNTAYACNGTNGAYTTYGAYAGYCCNAAYMGNACNMGNACNCCNMGN TCNTCNGCNGCNTTYTAYCARCARATGATHAARGAYCAYGGNTTYATHAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TTYGGN GTNGCNATHGTNYTNYTNYTNTAYCARATGTCNYTNATHGTNGGNATGGCNMGNACNATG TCNTCNAAYCCNYTNGTNCAYGARGARGGNMGNGARATGGGNGGNGTNATHATHATHYTN GTNTGGACNGGNATHTCNMGNTTYTCNCCNTTYTGYMGNTCNMGNAGYCARAGYCCNAGY AGYYTNATGACNTGYYTNYTNYTNGTNGCNATHACNYTNGGNGTNGCNCCNYTNGTNATG TGGTCNYTNTGYTTYGTNAGYGAYTGGCAYAARTAYYTNGGNCAY--------------- ------------------------------ACNGAYCARYTNTAYTTYCAYGAYGARAAR GCNGTNAGYGARTCNTCNYTNAARTGYGTNATHTGYGAYAARAARTTYGAYGAYTTYATH ACNYTNCARTGYCAYYTNGCNACNCAY---------ATHGTNTAYAARTGYGARATHTGY TCNAARACNTTYAARGAYAAYACNGARTTYAARAARCAYAARAARATHCAYYTNGGNGGN AARMGNTTYCARTGYGARATHTGYCARAARTGGTTYGCNAARACNTCNAGYATHGARGCN CAYATGMGNATGCAYTCNGGNGARAAYGCNTAYAAYTGYGARTTYTGYGAYAARACNTTY TCNACNMGNTCNGGNMGNTAYTAYCAYTCNYTNACNCAYTCNGGNATHAARMGNTCNAAR TGYCAYATHTGYCARAARGARTTYGTNMGNAAYMGNGCNYTNAARATGCAYYTNAARAAY CAYGTNGTNGAYAARCCNYTNGTNTGYGARATHTGYGGNGARGARTTYYTNYTNCAYTCN CARYTNGAYGGNCAYYTNGCNTAYCAYMGNGGNGAYAARCCNTTYMGNTGYGAYGARTGY GGNAAYACNTTYACNYTNMGNTCNAGYYTNCARMGNCAYATGCARYTNCAYACNACNGAR AARGCNTTYGTNTGYGGNATHTGYGGNAARCARTGYTCNCARGGNTGYAAYYTNAARGCN CAYATGMGNACNCAYACNGGNGARMGNCCNTAYTCNTGYGAYYTNTGYGGNMGNGCNTTY GGNATHAGYTCNCAYYTNTAYMGNCAYATGMGNATHCAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GAYTAYAAYATHGGNATHYTNGAYGTNGARAARCCNTCNATHTGYAGYTGYCARGAR YTNYTNGAYTCNAARACNGTNATHCAYAGYGGNTTYATGMGNAARMGNAGYYTNMGNAAY MGNATGATHAARATGYTN------TGGCCNCARGTNTAYGTNGTNGTNTCNAARCARTGY YTNTAYTGYTTYACNAGYGARACNTCNGTNAARCCNATGAARGCNGTNTCNYTNTAYGGN TTYAAYMGNATHTTYMGNGCNAARGGNGAYAARGTNAARGGNGTNGTNTGGGCNTTYAAR YTNGARCAYATHCARCCNACNATHMGNTCNYTNTAYTTYTCNGCNCCNTCNGARAARGAY ATGYTNCARTGGATGMGNATHATHAARCARGARATGYTNTCNGCNAAYGGNAARGGNAGY MGNATHTCNACNGTNGAYTCNCARTAYGGNGARTCNATHGCNTCNGARAAYTCNTGGGGN TCNGCNGARTAYAAYTTYATHGARAARAGYATHTAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGACNGAYTCNAARTCN AGYYTNGCNMGNGAYGGNACNATGCARGTNACNGCNAARGARGGNATHGAYTAYYTNAAR TCNGCNAAYAARGAYACNYTNYTNAARGCNCARGGNYTNGTNAARGAYAARCCNGCNGTN CARMGNGAYGGNACNATGGTNTCNACNGCNAARGARGCNGAYMGNYTNYTNGAYGGNAAY AARCCNGAYGCNGAYGCNCARACNMGNGGNCARCARAARCARATHGAYGAYYTNAARAAY ---------GARCCNAARGCNAARAARGCNAARYTNGCNAARGAYGGNACNATGGCNGTN ACNGCNAARGARGCNAARGCNYTNYTNGCNGGNGARAARYTNGGNGAYACNMGNCARGAR ACNTCNAAR---------AARTCNAARACNCCNYTNMGNAARAAYACNACNATGGCNAAR ACNGTNGARGARGCNAARGGNGTNYTNGAYGGNACNGTNGAYYTNAGYGARGGNMGNAAR ACNMGNTCNCARAGYMGNGGNGAYGTNCCNAARCCNTCNATHAARAARCARGGNACNATG CARCARACNGCNAARGAYGGNAARGCNTTYYTNAARMGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GTNGAYGGNGAYAAYGGNGCNMGNACNAGYCCNAGY MGNTTYGAYGTNGARTGYTCNTAYATGAGYCARCAYMGNGGNAGYTTYAGYTCNGAYCAR AGYACNCCNCCNGARAGYCCNCAYAGYAAYCARCARTTYCARYTNAAYTCNGTNAAYGAY GGNMGNCARMGNMGNACNATHCCNTCNGCNCCNGGNYTNCARTAYMGNTCNCAYAAYTCN AGYGAYTCNAGYYTNGARMGNCAYAGYGTNGAYACNAAYGGNAGYGAYGAYGCNGTNYTN GCNCCNGARTCNATGMGNGCNCCNTCNTCNMGNYTNCARCCNCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGCCNAGYATHCCN ATHATHAARCAYATHATGGCNGCNYTNGGNGGNAAYAARGCNAARGCNGCNGCNTCNATH ATG------------CAYATHGTNAARCCNCAYATHCCNATGATHMGNTTYCCNACNMGN GTNCCN------------GGNTCNYTNTCNTCNGAYATHAGYAAYCCNAAYACNGTNGAY TCNYTNGTNTCNCARACN---------------GTNGCNTCNAARCCNAARGCNGCNAAR TCNAARGGNCCNACNATHGAYGCNAGYGARYTNCCNGTNMGNTAYMGNMGNAARCCNATH TCNATHGARGARATGGARTTYATHGARAARGGNGGNCCNGTN------------------ ---------------------------------------AARMGNCARTTYGGNATHTGY GTNGARGARTGYAGYYTNATHATHMGNTCNATHACNTCNAGYCARTGYCCNGAYGGNCAR GTNTGYACNTCNAAYGGNTGYGGNCAYGTNTGYCAR---------------CCNGCNCCN GGNGCNCCNAARTGYTCNGGNGTNATGTGYGCNATGTAYTGYGARAAYGGNTTYGCNYTN GGNGAYGAYGGNTGYCCNGTNTGYAARTGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GCNCARGARGARGCNYTNGARGARYTNMGNGCNGAR TCNGARGAYYTNTAYYTNGCNGCNATHCARAARGAYGAYGARGCNYTNCCNYTNAGYTTY GARGGNCCNAARGARACNCCNCCNATHAARGAYTAYGCNCCNCCNGAYGGNGARTAYGTN GAYACNACNMGNAARTTYATGTCNYTNAGYAGYGAYATGGAYTGGAAYATHGAYATGGAR GTNAAYYTNTTYCAYGCNATGMGNGGNCAYAARCCNGCNGGNGTNAAYMGNCAYTTYCAR ATGATHGCNATHCAYGAYAARYTNAGYTCNTCNGCNAARAARGTNACNTCNGGNGAYGTN TGGAARCAYYTNACNACNYTNTAYGAYYTNCAYGCNYTNAAYGARTCNGARATHGTNCCN TTYCCNAAYAARGAYGGNGAYTTYTCNYTNAAYGARAARGARATGGTNGAYTGGTGYTCN AARTCNTTYCCNMGNTCNTCNTAYATHTCNACNGTNACNGCNGAYTCNACNAARACNGAR GCNTTYGGNAARAAYATHTCNAARYTNAGYGCNAARYTNGARACNAARTCNATHTCNCAR ACNCCNAARYTNGARTCNAARYTNGAYCCNAARTCNGAYAGYMGNTCN------------ ------------AGYACNCCNAAYMGNACNGARTCNAARTCNTCNAAY------------ ------------TCNAAYAGYGCNTCNAARTCNCAYCARAAYACNCCNTCNTCNGTNCCN TCNCCNTCNCCNAARMGNACNAARMGNACNMGNAAYGTNAAYTCNGCNAGYGCNAGYCCN GCNACNCCNACNGARCCNCARGCNAARMGNMGNMGNATGAARGARGARTAYTGYGGNACN CCNGTNTAYATGGCNCCNGARATGAAYTCNACNTAYTCNTAYYTNGTNGAYGTNTGGGCN ATGGGNATHATHATGTAYTAYYTNYTNACNGCNTAYCCNAARGAYAAYYTNYTNAAYGAR GAYATHAARAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNAARYTNCARTTYAARCARYTNCARGARCARCAR CARCARAARYTNATGGARMGNMGNAARAARAARAARAAYGARCARAAYGARAARGARGAY AARAGYAARAARCCNGGNTCNGCNGCNTGYGAYATGAARGAYGAYYTNAAYYTNMGNYTN GCNGAYCAYACNGGNAARGGNTAYGGNTAYGTNTCNGARGARYTNGTNGAYCAYYTNAAY GAYCARATHMGNCARYTNAARGAYGARAAYGGNMGNGTNTAYAARYTNYTNAAYGARAAR GAYTTYGARATHMGNCAYTTYAARAARAARAARGARGARCARACNATGAAYACNATHGAY ATGAAYGTNACNAAYGARACNGCNTCNACNAARATHGTNGARYTNAGYAARAARGTNMGN GARYTNACNGCNGARAARGARTCNGARAARACNMGNTGYMGNCARTTYCARAARAARTGY CAYGAYYTNCARYTNCARYTNCARTCNGCNCCN---------GAYAAYCARTCNGTNATG GGNTCNATGGTNAGYYTNMGNTCNGCNATHTCNACNAARGARGAYGAYGGNGCNGARGTN AARGCNYTNCARGAYMGNYTNAARCARTCNGARTCNMGNYTNTCNGAYTTYMGNAAYCAR TGYCARCARYTNMGNCARGARYTNAARGTNGCNAAYAARGTNATGTCNCARGARATHGGN GARAAYGTNAAYATHCARTCNYTNYTNAAYGARACNAGYCARTGGMGNGGNMGNGCNCAR CARATHATHGGNYTNCARCARAARGTNGARGARYTNAARGCNMGNTAYGARGGNCCNCCN GCNGGNGARAGYACNGGNATG---GAYAARGTNTCNACNGCNMGNMGNMGNCARGARGAR AARTAYMGNGARGARYTNMGNMGNGCNGARAARGARMGNAARGARGCNCARGARACNAAY ATHAAYMGNYTNAARCARYTNGARGARGAYTAYTCNCARATGAARAAYAARYTNGAYGCN TCNAARACNMGNAAYAARGTNYTNTCNAAYGARATGAARGGNYTNAARGCNCARGTNCAR ACNYTNYTNAARAARAGYCARAAYGAYGAYGARTTYATHGARGCNYTNATGMGNCARCAR AARCARYTNAARGARATGATGGARACNACNACNTCNAARCARTCNGTNGCNCAYCARGAR CARCARCARCARYTNYTNGCNATGAAYATGAARTTYCARCARGAYAAYAAYGTNGTNGAR CARYTNAARATGATHGCNGCNCARAARGARTCNCARGTNAARYTNYTNGARATGGARYTN GARCARYTNMGNAAYTCNCAY---AAYAAYCAYCARGCNTGGCCNGAYACNCARTCNGGN CCNAAYCCNACNTCNATHGCNACNGAYGAYGTNAAR------ACNGGNATHAAYAAYAAY AAYGGNACNACNTTYMGNYTNMGNGAR------AAYAGYCARYTNTCNAGYGCNMGNTCN GCNAGYMGNTCNATGTCNMGNACNCCNACNCARATGATHACNGTNGARCARMGNGCNATH ACNCCNATGAAYGGNGTNAARCCNCARGARTTYGAYGARYTNMGNTAYCARATHCARGAR YTNACNGTNATGTCNMGNTCNGTNGARGTNGARMGNGAYAARATGACNGARYTNGTNCAR GTNYTNCAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARYTNCARACNGARTTYAAYAAYAARCARGCNAARYTNCARMGN GARTTYMGNGAYAARGTNMGNTTYGAYYTNYTNMGNTCNTCNGGNATGCCNGAYACNGAR GTNGARAARGTNATHTCNGGNYTNATGTCNAAYATGGCNGTNGTNGARGARAARYTNGGN YTNGARCARGCNMGNCARMGNMGNGCNYTNGARCARMGNYTNGCNAARMGNAARCARGCN GTNGARTAYCARGARATHGARAARCAYGARAARGCNCARGARCARGARGCNAARGTNAAR GTNYTNMGNTCNYTNYTNGAYAAYCAYACNAARGAYGGNTCNYTNYTNGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNGAYTCNGGNGARTAYAARGTNGAYTGYATHGCNGARGGNAGYAAYCCNGAR GCN---GARGTNAAYYTNGAYTTYCAYGGNGTNGCNATH---GARGGNAGYTCNGTNGAR GCNAGYYTNATGGARCAYAARTTYMGNMGNTAYMGNACNACNTCNTCNGCNAGYYTNAAY YTNATGGTNAGYAAYTCNGGNCARGARYTNAGYTGYTTY------GCNTCNGAYGARTCN GGNACNAARAARTCNYTNAARATHGCNATHGARGTNAAYATHTAYGAYCCNACNATHGTN TGYAAYGAYACNGAYGCNTTYGTNGGNCARAGYAAYCCNATHYTNACNTGYGTNGTNAAY TAYACNAAYATGGAYGTNACNGGNTTYGCNTTYCARATHGGNGAYACNGGNGARATHATH AARAARGGN---------GARAARAAYGCNCARAAYATGGCNGTNAGYGTNATHGAYATH GARGAYGGNATHAGYGARGTNTCNYTNGAYYTNCAYAARGCNGARCAYAARTAYYTNAAY AARAAYTAYTAYGTNYTNATHGAYATGAARGGNGGNCAYACNAGYAARGARAGYGTNMGN YTNAAYAGYGTNCARGAYGARGAYGARGGNAGYGGNCCNGCNGGNAAYGGNGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARAARGAR GCNTGYGARATGTTYAARATGATHCARYTNTAYATGGGNGAYMGNAARGGNAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARAARYTNTCNACNGAYGCNGARGAYATHAGYATGYTNTTY GGNGAYGARGAYGTNGAYTAYMGNAAYYTNCCNAAYATHCCNAAYMGNYTNATGGCNCCN CCNCCNATGCCNTCNCARGTNYTNYTNTCNCCNTCNGTNAARAAYAAYACNCARAARGGN TGGAGYCARTTYAARGARGAYCAYCCNGAYGAYTTYGTNCARGARTCNGCNMGNAARMGN ATHMGNGARCCNCARATHCAR---GTNGARGAYGTNGAYYTNMGNCARMGNCCNTCNACN CARYTNMGNCCNATGCARCCNTCNGAYTCNAAYTAYCARTCNAARGAYMGNTCNAGYCCN GARAARGARCAYATHYTNAARCARGCNGARATGGAYYTNGARGARGGNMGNATHAGYYTN GARTAYTAYGARAAYYTNYTNMGNCARGTNGGNCARATHTAYAAY------AARCAYAAY GCNAAYATHCARAGY------------------AAYCCNGAYAAYGGNATGGTNGARGAR GGNTCNGGNTTYGARAGYGARMGNAGYAARGGNMGNTAYACNATHCCNAARAARAAYCCN GCNGARAARTCNATGAAYTAYCARGAYYTNMGNMGNAAYCARMGNTCNTAYGGNGAYMGN GAYATHACNAAYTTYAARACNMGNAARGGNGARAAYAAYCCNCARMGNTCNYTNMGNMGN GAYACNGAYTTYMGNCARTCNGGNCAYTCNCARGARMGNCCNGAYGARATHCARCCNYTN YTNGAYGARGTNCCNYTNCARGARCCNGTNCCNMGNCCNATHGCNCARCAYGGNTCNTCN GTNGCNCCNATGCARCCNGGNGCNCCN---------------------------CCNGCN YTNYTNATGGGNMGNCAYCCNGTN------CCNATHCARCCNGTNGCNCCNMGNCCNGCN GTNGGNCCNGARGCNMGNAAYCCN------------------GTNCCNATHCARCCNGGN GCN---CCNCARCCNGCNGTNATHGCNGTNTCNGARGTNMGNAAYCCNGTNCCNYTNCAR CCNGGN---------CCNGCNYTNATHCARCCNGGNGCNCCNYTNATHGGN------MGN ACNATHTCNGAYCCNTTYGAYGAYCCNMGNTGGGCNGCNATGAARGGNYTNYTNGARCAY GARGGNACNGARGARATHGTNYTNGAYGAYAARCCNTTYGARYTNMGNATGGGNACNGCN MGNAARYTNACNYTNTAYGGNCARGTNTTYCARATHGGNGTNGAYYTNAARGARMGNGGN ATHMGNYTNAAYGGNCARYTNGTNTAYAARYTNGGNGARCCNATHAARGARGTNAAYYTN AAYGGNMGNMGNGTNMGNYTNTAYTAYCAYGGNYTNTCNAARGCNATHTGGYTNGAYGGN CARTAYCAYGARATGMGNYTNGAYGCNCCNCCNMGNAAYTTYYTNGTNGAYGGNAGYCAR MGNGGNTTYCARATHGAYGGNMGNGAYATGATGYTNYTNGTNGAYMGNATGGARAARGGN MGNTAYGGNGGNCCNCCNMGNACNATHMGNATHGCNGGNYTNGARCAYCAYATHAGYTTY CARGGNCARCCNAARATHATHYTNATHAAYGGNAARCCNTGYGARATHAARYTNGAYAGY AARATHCCNTTYGTNGTNATHGARGGNAARMGNCAYGGNATHMGNTTYGAYGGNGARCCN MGNACNATHTTYATHAAYGAYCARCCNCAYGTNATHCCNATHGAYMGNGCNGARAARGTN MGNATHGGNCCNMGNCCNACNTAYATHGCNTTYGGNGGNCCNGCNCAYGARATHATHATH GAYGGNAARTGGTTYGARGTNMGNTTYGAYAAYACNCCNAARGAYATHCAYYTNGGNAAY MGNMGNTTYMGNATHMGNATHCCNGGNCCNCARCCNMGNGTNAARATHYTNGGNGARYTN GAYATGAAYTTYGAYTGYTCNMGNYTNATGACNGGNAAYGTNGCNGCNCAYMGNGTNATH CCNTCNACNAAYYTNCARCARCCN------GTNCARCCNYTNCCNACNGGNGTN---TCN ATHAAYCCNAAYAAYCCNMGNYTNYTNCARCCNGGNYTNCAYTCNACNGTNATHAAYGCN ------------------------------------------------------------ ---------------MGNCCNGTNCARACNACNGCNATHGTNACNCAYCCNYTNCARCAY CCNCARATGGTN------------ATGTCNAAYYTNGCNCCNGGNTCNGGNATG------ ------------------GTNCCNCARACNGARAAYTCNGTNATGMGNCCNYTNCARGCN GTNGTNGGNCARGCNYTNCCN---------------------CARGCNACNATHYTNCCN CARCARATHACNCAYCAYATH--------------------------------------- ---------ACNAAYATHGGNATHCARCARGCNGTNTCNACNATHCCNAAYATHCARGCN CARCCNYTNCARACNGCNATHGCNCARTCNAGYATHCCNGGNYTNYTNYTNAAY------ ---------------------------------CARAAYYTNAAYGCNATHTCNAAYYTN TCNGCNATHATHTCN------------------------------CARCCNAAYYTNTCN CAR--------------------------------------------------------- ---------------GTNCCNCARCCN--------------------------------- ------------------------------------------------------------ YTNACNACNTCNTCNACNGTNCCNACNGCNCCNGCNCCNTCNTCNACNTCNGGN------ ------------------------TTYGAYATHAAYAAYYTNYTNAGYAAYYTNYTNAAR GTNGGNYTNATHAARAARGAYTCNCCNTCNGARACNCCNAGYCARYTNAAYGCNTCNAAY GCNATHGCNCARGCNGGNACNCCNGCNCARAAYACNCCNATHGTNACNGAYCARAARCCN YTNCCNAARAARATHACNMGNGAYGTNATHCCNGAYYTNTCNGAYTTYGAYTCNGAYYTN YTNAARATHCCNTAYAARAGYGTNATHGARGAYYTNCAYCARGGNATHCARTGYCAYACN TGYTCNGCNMGNTTYACNTCNGARGAYAAYGARAARTAYMGNGCNCAYYTNGAYTGGCAY TTYMGNCARAAYAARYTNGARCARGARATGGTNAARGTNGCNAARAAYMGNAARTGGTTY TAYTCNATHGCNGAYTGGATHCARTAYGARGARYTNACNGAYATHMGNGARTCNTCNMGN AGYGCNATHTTYGARCARATGMGNTTY------GGNAAYCARAAYATHCCN---CARCAR CAR------------YTNTTYGCNTTYGARGGNAARGARGTNACNGARAAYCCNGTNGCN ACNGGNGTNGARGGNGARGAYATHTGYGCNACNTGYGGNGAYCCNTTYGAYCARCARTGG AAYGARGARACNGARGARTGGATHYTNAARAAYGCNGTNAARGTNAAYGGNAARACNTAY CAYCCNATHTGYTAYGARGAYATGCARGARACNCCNACNCCNGCNCCNGGNGTNGARTCN AAYCCNYTNACNGARGCNATHGTNTCNYTNAARCARGARCARGARYTNAARCCNGAYYTN AAYCARYTNCARGCNCCNATHAAYATGGARGARAARATHAARATHGARAAYCARGARAGY YTNGGNGARTAYAAYGCNGTNATHAARACNGARGTNGAYGAYGTNAAYGGNAAYTCNGCN TCNGAYGCNGGNATHTCNCARACNATHGCNGAYGTNCCNATH---AARGGNGARTAYTCN GARGGNGAYCCNGCNYTNCARTTYACNTCNGCNYTNACNAAYCCNAARGCNACNGGN--- ------------------------------------------------------CARGTN ATHTCNATHGCNCARGARGAYCCNAAYGCNCCNTGGGARATGGAYTCNAAYCCNACNCCN GARYTNTCNMGNACNCCNAGYCCNGTNCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ACNGTNAARAARGARTTYGARTGYGAYACNTGYGGNYTNGGNTTYAARTCNAAR GGNAGYYTNGTNAARCAYYTNMGNATGCAYACNMGNGARMGNATHTAYYTNTGYGAYGTN TGYMGNATGMGNTGYAARACNAARGGNGCNYTNAAYACNCAYTCNMGNTCNCAYTCNYTN TTYGTNTGYGAYTCNGCNGAYGGNTGYGGNAARACNTTYAARTCNMGNAARGARTTYMGN ATGCAYGARMGNTAYCAYTCNAGYGARAARCCNTTYYTNTGYGAYTGYTGYGAYMGNMGN TTYACNACNAARGGNYTNYTNGARCARCAYGCNMGNTAYCAY---GAYAGYGARGARGAR GAYAGYGAYGARTTYACNGARGARGARATHGCNAAYGAYCCNTCNAARMGNATGYTNTGG GCNGCNGARAAYAAYAARGTNGAYATHGTNAARGCNYTNYTNCARGARGAYCCNAARYTN GCNYTNGTNAARGAYAGYGAYGGNTAYACNCCNYTNCAYMGNTCNGCNTAYAAYAAYCAY YTNGAYGTNGCNMGNYTNATHYTNTCNGTNAAYCCNGAYATHCAYGCNMGNACNATHGAY GGNTGGCARCCNYTNCAYAGYGCNGCNMGNTGGAAYTCNGTNGARACNGCNCARYTNYTN ATHTCNAAYGAYGCNGAYATHAAYGCNAARACNAAYGGNAAYYTNACNCCNYTNCAYATG GCNGCNTCNGARMGNAAYAAYCAYAARATGYTNGARYTNYTNYTNAAYAAYCCNTTYATH GAYATHAAYGTNATHTCNAARGCNGGNGARACNGCNAARCARATHTGYCARMGNACNAGY GCNCAYTAYTCNATGTTYGARATHGCNAAYYTNAGYATHCARAARYTN---------CCN GTNAARACNATHAARGAYTAYGAYCARCARGTNACNGTNYTNCARAARGARAAYTTYAAY YTNAARYTNMGNATHTAYTAYYTNGARGARMGNATGGARCARCARTAYGGNAGYGARCAR GAYGTNTTYAARACNAAYGTNGARYTNAARGTNGARGTNGAYCAYYTNACNGARCARYTN GARGARAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CCNTTYTAYGGNTCNGARGARATGYTNMGNCCN TGYCARAAYYTNGARGTNAARMGNGTNCCNGGNCARAGYTCNMGNACNTCN--------- ------------AARCARGARGAYGARAARYTNACNTGYCCNTGYTGYYTNTGYAAYGCN AAYYTNYTNAARYTNCARTCNYTNYTNTGYTCNACNTGGGTNACNCCNGCNYTNTCNMGN CAYATHYTNGAYYTNYTNTGGGAYAGYATHCAYYTNYTNTGYYTNACNAARACNGAYATH AARAARGCNACNGARYTNATHGTNGAYAARTAYCCNGCNGTNATHTCNAAYTAYGCNTCN YTNTGYTTYCARGGNGAYYTNGARAAYTAYGCNTAYATHYTNAARTGYATGGARAGYGTN YTNAARGARTGYATHTCNCARACNAAYGARAAYGARATGYTNTAYATGAARGCNTAYAAR GAYYTNYTNAAYMGNYTNTCNGARYTNTTYCCNCCNTCNCARTTYATHCARYTNYTNCCN AARGAYGGNAGYATGTTYTTYYTNYTNCCNTTYATHATHMGNAAYATHGARTTYGARAGY ACNAAYTCNYTNAARMGNGAYATHATHGAYATGGGNAARCARYTNYTNTCNCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARACNTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATHYTNAARGAYATHAAR TCNTCNGTNTCNTAYMGNAAYATHGCNMGNTAYGARTGGAARGARAARGAYAAYACNACN TAYGTNMGNGCNGCNTAYYTNMGNMGNTTYGAYCCNAAYCCNTTYCAYCAYGGNACNAAR GTNAARACNYTNYTNGARACNAGYATGACNTGYATHYTNAGYAAYYTNGAYATGTAYGAY YTNGARGAYTTYCARGAYGAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TAYMGNCCNTGGGAYCARTAYAARAARGGNTTYGGNAAYAAR AAYGGNGARTAYTGGYTNGGNYTNGARAAYYTNTAYCARYTNACNAAYAARMGNAARTAY GARYTNAARGTNGAYYTNGAY---TTYGARGGNGTNAARGTNTAYGCNMGNTAYTCNTAY TTYTCNGTNGARTCNGGNGCNGAYGGNTAYAARYTNCAYGTNAGYGGNTTYACNGGNGGN GCNGGN------------GAYTCNYTNGARYTNAGYAAYGGNCAR--------------- ------------------------------------------------------------ ------------------------------------------GTNCCNTAYYTNGGNAGY AARATHAGYYTNATHTCNAARGCNGARATHMGNTAYGARGGNACNYTNTAYACNATHGAY CCNAAYGARGCNACNGTNGCNYTNGCNAARGTNMGNTCNTTYGGNACNGARGAYMGNCCN ACNGAYMGNCCNYTNCCNGCNMGNAAYGARGTNTTYGARTTYATHATHTTYMGNGGNTAY GAYATHAARGAYYTNCAYGTNAGYGARCCNCCNAARTGYCAR---YTNGAR---GGNGTN YTNTCNGAYCCNGCNATHGTNAARTCNTCNCARCCNCCNCCNGGNCCNGCNGGNGCNGCN TTYCARGGNCARCCNCCNCCNGGNGGNTTYCCNGGNGGNCARCCNTAYCARCCNTTYGGN CARCCNATG---TTYTAYAAYCARGGNCARCCNGCNCCNGGNTAY------CCNCCNCCN CAYCAYCCNCCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYTAYCCNTCNGAYGTNGARGTNTCN TAYGAYGARTTYAARTAYGTNGARGCNGTNYTNCCNAARTCNACNGTNCCNGARYTNCCN CAYCAYACNTCNTAYCCNACNTCNTCNGGNTGGTCNCCNCCNAAYGAYGARYTNMGNAGY CARCARCCNTAYYTNATHMGNMGNACNAARAAYCAYGTNYTNCCNGTNTAYCCNGTNCAR AARGARGTNTGGGGNMGNATHAARCAYCAYATHGARGTNAARMGNATHGARGGNGAYATH TGGAARYTNGARGGNGARYTNMGNCAYTTYYTNATGGARAARTAYGGNYTNGARAAYYTN TAYACNCARGTNCAYGARGTNAGYMGNTGYGTNMGNGTNMGNGGNCARTAYCAYGAYGAY ATHGCNCARTTYYTNYTNGAYAARGGNATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNGAYTCNAGYTAYAAYCAYAAYAGYTCNGTNTTYYTNGTNCAYTTYCARAGYTCNCCN TTYGTNATHGTNAGYMGNACNMGNGTNMGNGARATGACNYTNYTNGARAARGCNATGACN CAYGTNTTYGGNGCNGAYAARYTNAGYGAYATGCARYTNTCNGAYMGNAAYGTNTTYTCN YTNGCNGAYATHGTNYTNMGNAARTCNCAYCARAAR---TCN---TTYGTNMGNMGNYTN CARGARGGNAARGARAAYCCNYTNTCNTCNTCNAAYGAYMGNAARMGNAARCARTCNGAR GAYGTNYTNGARGAYATHGGNGTNATGGAYGARAAYAARGCNGARAARMGNTCNMGNYTN AARYTNATHGARAARAARTTYGGNGARGARGAYCARCCNGTNYTNGARAARATGGARTAY AARTTYGTNATHGGNTTYCAYGGNCARCCNATHACNGAYGCNGARTGYMGNAGYCAYGTN GARYTNAARGGN------------------------------------------------ ------------------------------------------------------------ ---------------------------CARTAYCAYGTNAAYAARYTNGTNYTNGTNGGN GAYCARGARCARYTNCCNGCNACNGTNYTNTCNAARGARGCNAARAARAAYMGNTTYGAY ACNTCNYTNTTYCARMGNATHCAYTCNAARTTYGAR------------AARGAYACNCCN ATHATGATGYTNAARCARCARTAYMGNATGCAYCCNGAYATHYTNAARYTNCCNAAYTCN TAYTTYTAYMGNAAYCARYTNATHACNGCN---GARTGY---TGYACNMGNAAYTCNAGY YTNMGNCCNTAYATHGTNTTYGAYATHYTNGAYGGNGTNGARAAYACNGGNAAYCARGGN TCNAARTCNAAYNNNAARGARGCNACNTGYGTNGCNGTNYTNTGYCARMGNGTNATHAAR YTNATGACNCARACNACNAARTAYGCNGARMGNCAYATHCARGAYAARATHGGNATHATH TGYTTYTAYTCNGAYCARMGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AGYCCN AGYGCNMGNTCNATHYTNGARTCNGTNAGYAGYGARTGYTCNAGYGCNGARATGAARGAR AARYTNYTNYTNGCNATHGAYAARAARGTNCARATGAARATGGCNTCNAGYCCNGCNAAY ACNYTNAARAAYCARGGNAGYCARATHCCNMGNTTYATGGCNTTYYTNAAYAARAARMGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CCNGCNCCNCARYTNGGN AAYTTYCCNAAYCAYCCNATGCARGGNCCNGCNCCNCARTGGYTNMGNGGNCCNYTNATH GGNGGNCCNGGNCAYAAYCARCARTTYGAYCCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGCAYTTY GGNTCNAARTAYGTNTAYYTNGGNAAYGARCARGARGAYGARGARGARGTNAARGTNTCN ACNGTNGAYGAYGTNGTNYTNTCNGCNAGYGAYGTNAGYGAYGAYGAYGGNGARACNTGY YTNYTNGAYATHYTNGAYACNGCNGGNCARGARGARTTYTCNTCNYTNAARGAYCARTAY GTNMGNTCNGGNAAYGGNTTYGCNATHATHTAYAGYATHATHGAYAARGARAGYTTYAAY GARGCNGARGCNATHTAYMGNTGGYTNAARMGNYTNMGNGAYGAYGCNAGYTGYCAYGTN GTNYTNATHGCNAAYAARCARGAYYTNAARGGN------GARGCNACNGTNACNGAYCAR GARGGNAARGAYYTNGCNCARAARYTNGGNGTNCCNTTYTTYGARACNTCNGCNAARGAY GGNTCNGGNGTNACNGAYGCNATGAARGGNYTNGTNMGNAGYATHCCNMGNGARGGNAGY GAYTAYAARATHGTNATGYTNGGNAGYGGNGCNGTNGGNAARTCNAGYATHACNYTNMGN TTYGTNAAYAAYGTNTTYGTNGAYGAYTAYGAYCCNACNATHGARGAYTCNTAYMGNAAR ATGATHNNNNNNGAYGGNYTNNNNGCNNNNAGYAANGAYNNNAARAARGCNNNNAARAAR NNNAARNNNNNNNNNAARACN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TAY GCNTCNCARGTNGTNATGAARACNGCNATHATGGGNCARTCNAARYTNGTNGAYCAYATH MGNMGNAGYTAYAGYACNAGYGAYYTNACNGAYGAYGGNCAYTCNGTNATGCARMGNCAY GARGCNATGTCNGARGARTCNACNGARGAYGARYTNGAYAAYMGNYTNAARGARGAYAAY GCNGARYTNGARGARMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MGNGARCCNTGGGARGAYGAYACNTCNGARATHACNAARAARATHYTNAARTCN CARGCNMGNTCNCARTCNGGNAARMGN---TCNGTNTAYCARTCNCCNGGNGCNGTNATG TCNTCNCARTCNTCNAARAARGTNMGNGAYYTNGCNMGNAARATHMGNATHAAYTCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CAY TTYAGYGCNGAYCCNGCNYTNMGNCAYCARTCNTCNYTNGTNCARGARTAYATHGAYYTN YTNGARMGNCARMGNCCNATHGARGAYTCNGAYGCNAAYGARGARGCNAGYGGNGARAAY MGNYTNTTYAARGAYGTNCCNMGNAARTGYTCNYTNGTNGAYATGTCNGTNATHACNACN YTNTAYTAYTGYTCNYTNTAYCAYTTYGAYYTNTCNGARAAYTCNYTNGGNAGYCCNTCN GCNATHAARAARMGNCAYCARATHACNGARAARCARTTYGTNTGGACNTGYATHGGNGCN MGNTCNAARYTNMGNCARTGGAARGAYATHGARACNATHYTNACNACNAARGGNTGGTTY GGNGGNACNAARYTNAARGCNGTNATHGGNTTYGAYAARATHGTNGGNATHYTNCARAAR TAYAAYGCNCCNCCNGAYGTNATHGAYAARTAYYTNGCNYTNATGGAYGAYCCNGAYCAR MGNYTNGCNYTNGCNYTNAARATHAARTGYCAYAARACNGTNATHGAYACNTAYGCNTCN YTNAARGAYMGNGGNTCNYTNGARACNTAYGCNTCNAARYTNGAYMGNTAYTCNAARGAY GGNYTNTAYGCNTAYGAYGTNYTNAAYGGNTCNYTNATHAARTGGAAR---------GCN GCNGGNYTNTCNACNGTNATHAARGARACNAARYTNGGNGCNAGYGTNGARACNACNCCN GCNGTNCCNGCNCCNGTNGTNGTNGARAARCARAARGCNATHGTNAARCCNCARGTNATH ACNCAYGTNATHGARGGNTTYGTNATHCARGARGGNYTNGARCCNTTYCCNGTNCARCAR ACNTGYYTNYTNCARGARTTYATHTGYCCNAAYAARATHAAYGGNYTNGARAARGARTCN GARGARGAYGGNGCNAGYCAYGAYGARGARCCNCCNACNYTNYTNCCNCARATGGAY--- ------------GCNMGNGTNCCNAGYCCN---------------------------ACN ACNATHATHCAYTCNCCNAAYAARGARGCNGARTGYGAYTCNTGYCAYAARGTNGCNATH GTNTCNGCNCARATHGGNTCNCAYTAYTTYTGYTCNYTNTCNTGYTCNMGNMGNTTY--- GCNTCNCARTCNMGNMGNGCNGGNYTNYTNAARACNAARGTNCCNTCNMGNAARMGNAAR CARATGACN---GGNCAYAARGAYTGGAGYYTNTCNAGYAARAAYGARGGNYTNTAY--- ---------TCNGARATGGARGCNAGYGARCARGARGTNTCNCARATGCAYCCNGCNAAY GAYGARATGAGYAGYTGYAAYTCNGTNCARGARACNAGYTCNTGYGCNACNTCNCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYCAYACNTCNTCNCARGTNGAYGTNAAYMGN MGNAARGAYMGNGCNGTNATHAARCAYYTNTAYTAYAAYGAYTAYGARAARACNYTNAGY CAYTCNTAYAGYCCNYTNGTNAARYTNCCNGAYTAYACNTAYYTNGAYGGNMGNCCNACN GARATGMGNYTNTCNGAYAARACNAARCARATHAARAAYTAYGAYYTNGCNAARCARGTN GTN--------------------------------------------------------- ------------------------------------------------TTYAAYAARGAY TCNAARTCNTTYYTNGTNGCNGCNGGNTAYYTNGTNAARTCNGCNAAYAAYTCNYTNCCN GCNYTNACNGCNTGGTGGMGNGGNAAYAGYTCNGGNATHYTNGAYGTNACNAAYCCNGAY GCNGTNTCNTGGTTYYTNAAYAARACNAARTAYYTNCARAARCARTAYAAYATHACNTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN YTNGARTGYMGNCAYTGGAAYGARACNMGNGAYCCNCCNTCNCCNTTYTGYGGNCAYMGN AGYCCNMGNCAYACNTGGACNGARAARGCNCCNMGNGGNATGTTYTTYMGNYTNGCNTGG GTNCCNATHGGNTGYMGNYTNCARMGNMGNAARYTNMGNYTNAAYAAYCAYGTNATHTAY YTNATHGGNGAYTCNAAYATGATGGARMGNTAYGGNYTNTGYTAYATHATHAAYAAYMGN GTNGAYGCNATHTCNGGNAARTCNAARTAYTGGCAYGAYCCNACNGAYTGYATHAAYATH CAYTAYAAYYTNAAYGTNAARTGGMGNAAYCAYGGNYTNCCNTTYCAYAGYAAYACNGAY CAYTGGACNMGNATHAAYTTYAARAGYCCNGCNTCNACNYTNGAYGARATHCARCCNAAY ACNGTNGTNGTNATHCAYYTNTTYATGCAYTAYTCNACNCAYCAYCAYACNGTNTTYCAR AAYACNGTNMGNGCNACNATGGAYGCNTGYAARMGNYTNYTNGAYMGNAGYCCNACNACN MGNATHTTYATHMGNGGNCCNCAYGTNAGYTAYAARGARTGGCCNGCNCAYYTNGGNGGN GAYGCNCARGGNCCNYTNTTYYTNAARATHYTNMGNGAYGARTTYAARGAYYTNTAYGAY AARGTNTAYYTNYTNGAYTTYTGGGAYATGACNATHGCNGCNGARAAYGTNGAYYTNCAY ATGTCNYTNGARYTNGTNTCNAARTGYYTNGAYYTNGAR------GAYYTNGAYAARGTN CCNGGNACNAGYAARAAYGCNAARAARAARYTNAARACNAAYGAYGCNATGAARATHATH AARACNGAYMGNCARGGNGTNTGGAARGARYTNMGNAARGTNMGNAARCARCARYTNAAR GARYTNGCNAARAARMGNAARACNGARAARTTYAARTCNGCNATHGARAGYTAYAARGAY GARTTYGAYGTNGAYTAYACNGAYAGYAAYGTNGARACNYTNATGAARATGTCNAARYTN GGNAARGTNAARAARGAYCAYGCNCARAARATHYTNTAYCARCARCCNTGYMGNYTNTCN MGNGAYGTNGAYCARCCNCCNGARGARACNGARCCNACNTCNATHTTYACNGARGARGAY TTYGARAAYTTYGCNMGNGAYTAYAARCCN---------ATGTCNGCNCCNCAYGTNGCN GGNGGN------------AAYCARCAR---------------------GAYMGNCARAAR MGNAARYTNYTNYTNGARCAYATHCARGARCARAARAARMGNYTNCARCAYGGNCAYCAY TCNTCNGTNGCNACNCCN---CCNCCNGCNGTNATHACNAGYCCNGGNATGATHGGNGCN AGYCAYCCNACNGGN---TCNGGNATHTCNGCNGCNGARTAYGCNACNATHAGYAAYCCN CAYCARMGNACNGCNYTNCARCAYGCNCAYGCNAAYTCNGTNGGNTAYTTYATHACNCAR GAYTCNTCNTTYGGNAAYYTNATHYTNCCNGTNYTNCCNMGNATHCCNGAYACNAAR--- ---------GGNGGNTAYCCNATGAAYCCNGGNCCNGAYCCNGCNAARCCNGGNGGNYTN GCNAARGAYAARTGYGTNATGGCNGAYGGNYTNAAYGARGCNYTNTGYTTYGCNTTYMGN ATHGAYAAYACNGGNCCNCCNAARAAYATHGARGARATHYTNTCNAAYTAYGARATHYTN MGNGCNGARTTYCCNAAYGCNACNATHTTYGCNTCNACNTTYGAYAAYTTYGTNGCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNACNTCNTCNGAYTTYTTYMGNGARMGNMGNTTYMGNCCNGARAARGARGGNGTNGAR CCNGGNYTNAARGCNTAYTGGAARGARYTNCARTAYGAYAGYACNGGNGAYGCNGAYATH GARTGYMGNAARAAYAAYTCNTTYYTNMGNAAYGGNATGAARTCNATHYTNGAYCCNYTN ATHAARMGNTTYAARCCNAAYACNATHMGNTAYAARACNAGYGTNACNGARATHGAYTTY ACNGCNTTYAAYACNTTYAAYGCNMGNAAYMGNTCNTGYAGYGAYGTNACNGTNACNAGY TCNGAYGGNAARAARTTYGARGCNAGYCAYGTNATHGTNGCNATHCCNYTNGGNCAYYTN AARACNAARGCNCARTCNATGTTYMGNCCNTCNYTNTCNAARCARMGNYTNGAYGCNATH GAYGCNATGGGNTTYGGNTGYGTNGGNAARGTNTTYYTNCAYTTYGARGCNGGNATGYTN GCNGAYCCNGCNAARATHGCNAARGARMGNGARAARGARGARMGNGTNMGNCARGCNMGN GARMGNYTNGAYGGNGARMGNAARAARAARYTNGARGARATGAARGARCARCARMGNCAR GCNCARGARAAYMGNGARAARCARYTNGARATGMGNMGNCARAARATHGARGAYYTNMGN AARMGNGAYTCNGARMGNMGNGCNGCNGTNGARGARMGNMGNMGNATGAARGARGARATH GARMGNYTNMGNAARGARTCNATHYTNCARAARGCNGAYGARMGNYTNGCNMGNTAYGAR GCNTGGMGNGCNGGNGGNMGNAARGGNAAY---------------------------YTN GGNAGYGGNGGNGGNACNMGNGARGGNMGNMGNTCNTTYGTNGGNGGNGGNCCNAAYTCN TCNGCNGCNTCNTCNATGTCNTCNTCNTAYCAYGCNGGNTAYACN------AARCCNAGY CCNGTNMGNATGMGNGARAARACNACNCCNMGNAARCCNMGNCCNGCNAGYGTNGGNACN TCNATGCCNAGYTTYGTNGGNGGNGARCCNGCNAARTCNTCNMGNAGYAARAGYACNGAY MGNATHGCNMGNGAYMGNTCNAARCCNMGNCCNAGYMGNAAR---------AARGAYAAR GCNGTNAARGAYTCNACNGCNTCNGGNGGNACNGARNNNAARAARGARGARACNGARGAY GARAARGAYGGNGGNAGYACNACNACNAARAARGGNMGNGCNTCNYTNTCNTTYTTYGAY MGNYTNGCNACNCCNAARYTNAARAARCAYCARGAYGAY------CARAARGAYTCNCCN MGNGARAARTCNTCNCCNATHGTNMGNYTNTCNCCNMGNAARGCNTAYTCNACNACNAAY YTNTCNATHATGAARAARAARTCNTCNTTYMGNGAR---MGNACNAARGARAGYTCNTCN ------------------------------ACNCCNAAR---------GTNAARMGNGAY TCNTCNGCNTCNTCNTCNMGNACNMGNACNCCNYTNGGNGAYAAYACNGAYACNTCNGCN AAYAARTCNTCNACNTCNTCNCCNMGNATHACNCCNCCNCCN------------------ ---CCNCCNACNTCNGCNMGNGCNGCNTCNCCNCAYGTNAARTCNTCNCCNAGY------ CAYACNGCNCCNGARGAYGGNACNGCNGCNCCNMGNTCNATGGGNGTNAAYCARGGNATH TCNAARGARGARTAYAARGCNAARATGGCNGARAARMGNMGNCARGCNMGNGARAARGCN GARAARGARGCNGARGARGARMGNMGNAARCARGARGARGARMGNYTNGCNGARGARGAR TGYCARMGNCARGARGARGARGARCARMGNMGNYTNGARGTNGARACNATHMGNYTNGCN GARGARGCNMGNAARGCNGARGARGARMGNYTNGARAARGCNATHGARGCNGARGARAAR MGNMGNAARGARGARGCNGARAARYTNGARCARGARMGNATHGCNAARGARGARGCNGAY MGNAARGCNAARGARGARGCNGARMGNATHGAYAARGARAARCARGARAARGCNAARMGN GAYGARGARGARMGNATGGARMGNAARAARAARYTNGARATGATHATGAARMGNGTNAAR ACNGAYCCNGCNCARGAYAGYACN------------GGNAGYAAYAGYTCNYTNAARYTN GARAGYCCNGTNAARTCNGCNGGNAGYTCNCCNAAYMGNAGYACNGTN------------ ACNTCNCCNGAYGTNCARGARAAYCCNCCNTTYGGNGCNGCNCCNTCNAAYCARGAYCAR GAYAAY------------------------------------------------------ ------------TCNTCNGGNTCNGARGAYGGNAAYGAYAAYAARCARAARAGYGCNACN GGNAGYGCNATHGCNTCNTCNACNAAYAGYYTNGAYAAYGAYGCNTCNCCNACNACNCAR CARGTNYTNACNCCNGTNGTNMGNAGYGCNTCNTCNGGNGAYATHATHGAYGCNGCNGAY GAYAGYTCNAARAAYMGNYTNGARAAYGGNGGNAGYYTNGGNTCNYTNAAYTCNAGYAAY AAYACNCCNGTNATHTCNAGYGAYAAYAAYACNGARTCNACNAAYTCNTCNYTNGARGCN AARTCNMGNTTYAARTCNCCNYTNYTNCARCARYTNGTNGARAAYAARGGNGCNGAY--- ---TCNTCNGGNACNCCNAARTTYAARTCNCCNYTNYTNCARAAYYTNYTNGGNAARACN AARGTNGGNGCNMGNATGAGYYTNTCNGCNAGYATGGGNGAYYTNAGYYTNAAYAARGAY AGYCCNAAYTCNACNAAYTCNACNAGYGCNAAYCCNYTNACNGGNGCNATHAGYCCN--- TCNYTNAGYCCNGCNACNTCNAGYAARGARATHTCNAARGCNGGNCARGAYGARGAYAAR GAYGTNGAYGARTCNAAYAAYAAYACNTCNACNTCNCCNYTNGCNTCNTCNGTNTCNTCN TCNTCNGCNGAYTCNTTYAARYTNGARTCNAAYCAYACNYTNAGYAAYGGNAAYAGYTAY GAYAAYGTNTCNAARCCNACNGARGAYAGYAGYAGYACNATGATHGAYTCNGCNYTNGGN GCNAGYATHGAYCCN------------------------TCNGGNTCNATHTCNGTNATG TAYAAYGGNCAYGGN------GGNAAYAGYCAYACNATGGARGAYTCNAGYATHGGNYTN CAYTCNCCNGARGAYAARCCNYTNAARACNTCNTCNCARTCNGGNCAYTCNTCNTCNCAR GARGARACNGARGARGARGARGARGARGARAARGGNMGNTTYGARGARTAYATHGAYYTN ATGGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNCARGTNGTNGAYTCNMGNTCNCCNTGGMGN YTNTCNTTYATHACNGAYACNATHTGGGGNTTYATHAAYTTYATHGTNYTNTTYTTYCAR ACNATGATHAAYCCNAAYAARAAYAGYAARGGNGAYAAYTAYACNTCNGAYCAYMGNAAR CCNGGN------------CCNCARMGNMGNATGGGNGGNATH------MGNMGNGGNGGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYGGNAARYTNYTNTTYTGYGAYCAYATHTTYAAY GGNTAYGGNAAYACNAARACNGAYTTYMGNAARCARGTNATGAARTCNMGNTTYGAYTAY ATHAARGGNTTYTCNYTNCCNNNNGAYTTYMGNTTYAGYCCNTCNCARGGNGTNCAYGGN CCNMGNGCNCCNTGGGGNGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARMGNGTN TTYAARGAYTTYAARGTNGTNGAYATHTGYGTNATGAAYAAYGGNATGTCNCCNGGNTAY ACNAGYGCNATHYTNTTYATGAGYAGYATHTAYGARGCNATHGARGCNGTNACNAAYGAY GAYGGNTAYTTYYTNCAYGGNGCNMGNYTNMGNGTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNGAYGAYGAYTTYGAYGARGAYGARGARGARGAR GTNGTNGARGARTTYAGYACNTAYGARMGNACNGARATHGTNACNMGNTAYYTNMGNAAR GTNTAYMGNTAYTGYATHTGGTGYGGNACNAGYTAYGARGAYGARCARGARYTNAARAAY TCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNGCNACNAARGGNCARATGAARAARGCNATGTCNACNYTNCAY AAYYTNATHMGNGTNTTYAGYYTNATHGAYMGNGAYAAYACNAARTTYGTNGARAARTCN GARYTNGARYTNYTNTTYAARGTNYTNGAYTTYAARGTNAAYGGNGAYACNGTNCAYGCN ATHATGGTNMGNCAYGGNGGNMGNMGNCARMGNYTNGGNYTNGARGAYTTYATHCAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CARACNCAYGARMGNGAR ATGTTYGGNAAYCCNTCNGGNTCNCCNGARTTYAAYAAYTTYYTNTCNATGYTNGGNAGY ATHATHGAYYTNAARGGNTGGAARCARTAYCCNGGNMGNYTNGAYACNACNAAYAAYYTN TCNGGNTCNAARTCNYTNTAYACNAARTGGAAYGGNYTNCARATHATGTGGCAYGTNTCN ACNATGYTNCCNCAYAARCCNCARGAYGARCARCAYATHGCNTTYGTNGAYGGNGAYACN CCNTAYCAYCCNAARACNATHAARTCNAARCARATHCAYATHACNGCNGTNGTNMGNCAR ATHCAYCARAARCCNAARGGNTGGAARTAYGCNYTNAAYGTNATHACNMGNTCNGAYGTN AARAAYTAYCCNCCNAARYTNCCNGAYAAYTGYATHTTYGARCAYGGNAAYTTYTTYMGN GAYYTNYTNATHACNAARTTYGTNAAYGGNGARMGNMGNACNTAYCAYTCNCCNTCNTTY AARAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGAYCAYCARTAYGGNATHGCNGTN ACNAAYMGNTTYGCNYTNTTYGGNGAYGARGAYGARGAYCCNTTYGARGCNATHTCNAAR AGYAARTCNYTN---------------AARGARGCNGCNGARAARAARCCNAARACNAAY AARGCNAARAARGGNAAYGCNGGNAARCCNGTNGCNCARGGNAAYGARAAYACNAARAAR AARGARGGN---------GGNGAYMGNTCNCARACNAARCARGCNGAYMGNGGNMGNGGN ---GGNMGNAAYMGNGARCCNMGNGARATHMGNGARAAYGAYGGNGAYAARMGNCCNCCN MGNMGNCARGGN------------------------------------------------ ------CCNMGNGAYAAYAARGAYATGAARGCNGGNGAYGARAAYGTNCCNCCNGARTTY MGNGARMGNCCN---GAYGGNGGNTTYAARMGNMGNGARGAYMGNGGNGGNGARMGNGGN GGNTTYGGNGGNGARMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNMGN---GGNMGNGGN GGNGARMGNGGNGGNAGYGGNTTY---GGNCCNMGN------------------GGNGAY MGNAARMGNGARTTYGAYMGNCAYAGYGGNTCNGGN---GGNGGNATHAARCCNGTNGAR AARAARGARGGNAGYGGNGCNCAYAAYTGGGGNAGYTTYMGNGAYGAYATHGARGARCAR GGNCARGTNAAYGCNGCNGAYGARTCNAAYGAYTGGGCNAAYCARCAR------------ GARAARCCNGAYYTNAAYGARAGYGGNGARGCNGARGCNGTNAAYGARGARGAYGCNCAR CCNCARCARATGACNYTNGAYGARTGGAARGCNYTNAAR---CCNCARGGNAARAARCAR CCNGARTTYAAYATHMGNCARGCNGGNGARGGNGTNGAYTCNGGNCARTGGAARGAYGGN GTNGARTAYCARAARAARATHGARGARGARGARGAYCARGAYGAYGARTAYGAR------ GARGGNGAYCAYAGYGAYCAYCAYATHMGNAAYAGYAARCARYTNGTNACNGAYATHMGN ATHACNTTYAAYGAYAAYCCNMGNMGNGGNMGNGGNMGN---MGNGGNGGNMGNGGNGGN ATGGARMGNGGNGGNAGY------------------GGNMGNGGNGCNGGNGGNGGNGGN GGNGGNMGNGGNMGNGGNGGNAAYAARAARGARTCNGCNCCNMGNTTYGAYGAYGARTCN GAYTTYCCNTCNYTNYTNAARACNGCNGCNMGNACNYTNTCNGGNGGNMGNAARAARTTY YTNTAYTCNGGNCCNATHTCNAAYAARMGNCAYGARGARGARGAYTGGTCNTTYGTNCCN AARGCNTCNACNCARGAYACNGGNACNAARTCNGCNGTNGGNGTNGAYYTNGAYAAYGTN TGGAGYATHMGNAAYGTNTCNYTNGGNGGNGGNACNCARTCNGTNMGNTCNGARCCNGTN TCNTTYAARCCNGARATHYTNACNAARACNACNAAYTCNACNTTYTAYTCNMGNCAYGGN GGNATGAAYGGNMGNACNAGYAGYCCNAAYGTNAAYAAYCARGGNAAYTCNAAYTCNGAY YTNAARAGYACNTCNAAYTGGTCNAGYTCNGGNCAYAARYTNGCNCCNACNGGNCAYMGN ATGAAYCCNCCNACNTTYCARAAYCCNACNGARAARGCNTTYMGNAAYTCNMGNTCNMGN MGNCARAAYCCNTCNCCNTTYGAYTAYGAYATGAAYGAYTTY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNCAYGTNMGNTAYAARAAYAGYAARCARMGNGTNAARGAYCCNAARGTNCAR GTNGAYAARAAYAARAARTAYYTNTCNAARAARYTNAARAARAARMGNTCNCARYTNGGN YTNACNTCNATHGARGAYAARAGYACNATHYTNGCNGARAAYCCNATHGAYAAYGTNTGG ATHMGNMGNTAYTAYCCNAARCCNMGNTTYGARATHGARGARGCNTTYAAYMGNCAYAAR GCNTTYGCNCARCCNGCNATGYTNGAYAAYGTNGAYGGNYTNACNTAYYTNAAYATGYTN YTNGAYTTYMGNACNAARAARCARACNAARTTYATGAARAAYATHMGNTCNACNYTNYTN YTNCCNTTYCCNTTYAAYTGGGGNAAYCCNCCNTCNATHYTNGTNTTYTGYAARGARGAR GARCAYACNAAYYTNGCNYTNTCNYTNGGNGCNMGNCAYGCNGGNACNCCNGTNGARGTN GTNAARTCNATHGARAAYGGNGTNYTNAAYCCNAARGAYTTYGAYCAYGTNATHGCNACN GCNGAYTGYGGNAAYGARATHGCNCCNGCNMGNTCNTAYTTYMGNGAYAARTTYCCNCAR MGNGCNAARGGNAAYATGGGNACNGAYYTNAAYGARATGTTYAARYTNTTYTAYTCNGGN TAYACNTAYGARTCNCARAGYYTNTCNGAYGCNCARGGNAARYTNCARGTNCCNGTNGGN CARYTNAGYCARCCNACNAAYGARYTNGTNGCNAAYTTYGARGCNTAYATHGAYTCNATH TGYAARCAYMGNAGYATHGCNYTNGGNCCNTTYATHCARTCNATGAGYGTNGTNGCNCCN CCNTCNCCNGARGARTTYYTNGTNCARGTNGARGARTAYGTNCCNGGNTAYCARAAYGAR GARGTNGAYTCNGAYGAYGAYGAYGARACN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARACNCAYGARATHTCNGAYTCNGARGARTCNGAYAAYCCNAARCARGGNYTNATGTCN AARTCNGARMGNCCNMGNGARAARTTYGARAARGARAARGTNAGYACNCARGCNGARGAY GARTAYGAYGCNGAYACNGAYGTNGAYGARTCNTCNAAYGTNGARAGYGARGAYMGNAAR CCNYTNTGYAARTAYGGNAGYAARTGYTTYMGNAARAAYCCNTCNCAYYTNCARGARTTY CAYCAYCCNAARAARMGNAARTCNGAYTGYYTNGARACNAGYAAYTCNATHCCNCAYAAR AARACNTGYACNMGNGAYGARAARACNYTNCARGAYGTNTTYGARGARGTNCARCCNTTY AGYYTNTTYYTNACNAARGTNCAYGGNATHTCNCARCARTAYAAYAAYGTNGCNGCNTTY AGYYTNAARGAYYTNYTNTCNCCNGARTGGGGNGARYTNAARTCNTCNTGYCAYTTYAAY TTYATGTTYGAYATHTCNTGGYTNATGGGNCARTAYCCNMGNCARTTYMGNAAYYTNCCN GTNYTNYTNGTNCAYGGNGAYCARAGYMGNGCNGARYTNGAYYTNAARGARGCNGCNTCN CAYTTYCCNAAYATHTCNYTNTGYMGNGCNMGNYTNGAYATHCCNTAYGGNACNCAYCAY ACNAARATGATGYTNYTNYTNTAYACNAARGGNYTNMGNGTNATHGTNCAYACNTCNAAY YTNATHTCNAAYGAYTGGTAYCARAARACNCARGGNATGTGGGTNAGYCARATHTTYCCN YTNAAR---ACNAAYGAYGCNGARCCNGGNGARTCNMGNACNAARTTYAARGCNTCNYTN YTNCARTAYYTNGCNGCNTAYGGNACNGCNAARYTNGCNATGTGGGARAARGTNATHAAR GARCAYGAYATGTCNTCNGCNAAYGTNCAYATHATHGCNTCNGTNCCNGGNMGNCAYGTN YTNGARCAYAARCAYTCNTGGGGNCAYYTNMGNGTNAARAARATHYTNTCNAGYACNGGN CCNGAYCARGGNATHGTNAARAAYTGGCCNGTNATHGGNCARTTYTCNAGYATHGGNTCN YTNGGNGCNAAYCCNGARGCNTGGYTNYTNACNGARTGGGGNCARTCNATGTCNACNTAY MGNAARACNYTNTCNACNAAYYTNCCNGCNTCNAARYTNCAYYTNATHTTYCCNTCNAAR GAYAAYATHMGNYTNAGYYTNGARGGNTAYAAYGGNGGNGGNTGYGTNCCNTAYTCNATH AARACNGCNAGYAARCARCCNTGGYTNATHCCNTTYYTNAGYCARTGGAARTCNGARGGN MGNGGNMGNTCNCCNGCNGTNCCNCAYATHAARACNTAYAGYMGNATGTCNCCNGAYGGN TCNGARGTNGCNTGGTTYYTNYTNACNAGYGCNAAYYTNTCNAARGCNGCNTGGGGNGCN TTYGARAARAARGGNAGYCARYTNATGATHMGNTCNTAYGARYTNGGNATHYTNTTYATG CCNTCNGAYTTYGGNAGYAARACNTCNTTYAARGCNAGYAGYCARYTNAAYAARATHACN GAYMGNGARAAYTGYGTNTTYCCNYTNCCNTAYGAYYTNCCNCCNGCNACNTAYGTNAAR GGN---AARAARTCNGTNCAYYTNTTYTAYGAYGTNGTNTCNCCNTAYACNTGGTTYGCN TTYGARGTNATGTGYMGNTAYAARACNMGNTGGAAYATHGAYYTNAARYTNMGNCCNTTY TTYYTNGGNGGNGTNATGAAYGARTCNGGNAAYMGNCCNCCNGCNATGGTNCCNAAYAAR GGNYTNCAYYTNTCNACNGAYGTNAARMGNYTNGCNGARTAYTTYGAYGTNCCNYTNAAR ATHCCNAARAAYCCNGCNGARYTNATGTTYGARAARGGNTCNYTNAARGCNCARMGNTTY YTNACNGCNYTNGAYATGAARTGYCCNGARAARGTNGARGCNGTNTCNMGNGARTTYTGG ATGMGNGGNTGGTGYMGNGAYGARGAYYTNTCNGAYGAYGAYAGYYTNGCNACNGCNGCN GGNAARGCNGGNYTNAAYCARCARGARATHCARGARYTNYTNGGNMGNYTNAARGAYAAR GAYGTNAARGAYMGNYTNAARTCNGCNACNGAYGARGCNYTNGARYTNGGNGCNTTYGGN TCNCCNATGATHGTNGTNGAYAAYGARGGNACNAARGARTGGGTNTTYGGNAGYGAYMGN TTYCCNATHYTNGCNCARYTNYTNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNACNYTNGTNGTNAARAGY MGNGGNGAYMGNYTNMGNATHYTNCCNTAYGTNGTNTTYGGNTTYTGYTGYYTNGGNGGN YTNTTYACNTTYATHGCNGAYATGATHGTNGCNAGYCARTAYTCNACNGAYGAYGTNGGN YTNTTYGTNGARGARTTYCCNCCNAARCCN------------AAYGAYGCNYTNGTNYTN GCNTGGGGNTTYGGNYTNGAYATHACNTCNGTNGTNYTNGTNGTNYTNGGNGGNTCNTTY CAYYTNGTNGCNGGNMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGNGAYCCN---------AGYGARGAYYTNTTYYTN CARAAYTCNATHCAYGGNATGATGCCNGCNTAYAARMGNATHGCNGTNGGNGAY---GCN AAYAARGGNGGNATHCCNYTNTAYCCNGCNGGNCCNYTNATGAAYCCNCAYCARCAR--- ---CCNTCNYTNGTNCCNTTYCARCARCAYCCNTCNTAYATHCCNATG------------ ---------------------------------------------------TGYATHGAY YTNACNGTNGAYATHGGNGGNGAYGAYGTNATHGAYYTNACNCARTTYAAYACNATHGGN GAYTCNCCNGTNCARGTNTCNAGYCCNTCNMGNAAYACNGGNACNMGNMGNMGNCARMGN GGNAGYGGNMGNMGNGGNYTNCAYMGNTCNMGNAGYAGY---------MGNMGNMGNATH YTNGGNGARTCNATHACNCCNTCNGTNTCNYTNCCNTCNTCNTCNAAYCAYGCNGCNYTN GAYAAYAGYGAY---------GARGARYTNCCNGAYATHCCNTTYGARATHCCNGARAAR TGYAARCARGCNAAYGCNAGYTTYGTNAARTCNCCNCCNYTNTCNATHYTNTGYCCNATH TGYYTNGAYGAYYTNAARCARYTNAARGCNAGYAARAARAARATHATGTCNACNGTNTGY GGNCAYATHTTYTGYGARGARTGYATHACNAGYGCNATHMGNACNYTNMGNTCNTGYCCN ACNTGYMGNAARAGYYTNTCNCARGCNAARATHCAYCCNYTNTTYYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------MGNCCNTTYAARTGYCCNTGYGGNMGNACNTTYGCNMGNAAYGARGARYTN ACNMGNCAYCARMGNATHCAYTCNGGNTAYAARCCNCAYMGNTGYAAYATHTGYYTNAAR AAYTTYGGNMGNAARGAYCAYYTNAAYAARCAYYTNAARACNCAYYTNCAYTCNTCNCAR AARAARGTNCAYYTNTGYAAYGTNCCNAAYTGYGGNCARAGYTAYACNMGNTCNGAYGCN YTNACNMGNCAYCARACNAAYGCNCAYGGNATGAARGCNAARCCNTCNAARTGGMGNCCN CAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------MGNGTNYTNTCNGARATGGAY GTNACNGCNCCNAGYATGAARGAYGAYTCNMGNCCNTCNTTYCCNMGNCCNAAYTGYTGY ATHGGNYTNTAYYTNGAYGCNYTNGAYGCNMGNCCNGAYAARACNACNACNGTNGGNTCN CARCAYGCNYTNATGATGTCNGTNATGGAYMGNYTNCARGARTTYYTNAARGGNTCNGAY YTNACNMGNATHAARGGNGGNATGGARGCNMGNCAYATHGGNGAYGGNGTNATHYTNGAR GGNGTNAARCAYAGYTGYATHATHGCNYTNATHTTYGAYAAYGCNCARGCNYTNGARAAY TTYTGGATHYTNTTYAARAARAAYMGNYTNYTNTCNGCNTTYCARGAYATHYTNGTNGAY MGNACNYTNYTNAARCAYACNAARTGYTCNAARYTNACNATHMGNGTNAARYTNTGGGAR GAYGARATHMGNGCNTGYYTNGARGAYYTNAARTCNMGNCCNGAYAARMGNCCNGCNYTN ACNAGYTCNGARMGNGAYYTNAARYTNATHMGNMGNGTNAAYACNTTYCARAARACNACN CCNGARGTNGTNGTNAARGCNMGNGAYGCNGARAAYMGNTTYGARCAYAARYTNGGNGAR TTYATGYTNACNATHAARCARATHYTNCCNCARTCNGCNACNGTNATHAARACNGTNAAR GARTTYYTNACNAAYATHMGNATGGCNMGNGGNGTNAARAARGCNAGYTAYGARCAYATH GAYCARTAYYTNYTNTCNYTNGAYATGYTNMGNAARATHTTYCARGAYATHGARMGNGAR GTNGTNCAYCCNYTNYTNCARGTNCARGGNATHYTNGARAAYGARCARCARMGNTCNYTN AARCARACNATHAARAARGCNGCNACNGARATHTCNGAYAAYYTNMGNCARGARGCNGAY YTNCARAARGTNMGNCAYAARGARTGGGARTCNAARGTNYTNGTNMGNGARCARGGNYTN TTYTAYGGNYTNATHAGYYTNATHCCNATGGCNGTNGAYMGNYTNACNACNATHGAYTAY AGYGTNGAYGARTAYATHAAYCARTTYCCNGAYATHGGNATHTCNACNTCNATHGGNATH CCNGAYTTYMGNACNCCNGGNACNGGNYTNTAYGAYAAYYTNCARCARTAYAAYATHCCN TAYCCNGARGCNATHTTYGAYATHGAYTTYTTYCAYCAYAAYCCNMGNCCNTTYTTYACN YTNGCNAARGARYTNTAYCCNTCNGGNAARTAYMGNCCNAAYTAYATHCAYTAYTTYGCN MGNYTNYTNAAYGAYMGNGGNATHYTNGAYAARATGGTNGARGCNCAYGGNACNTTYTCN ACN--------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------------------GAY GAYGAYGGNGCNATH---TCNGARACNGGNTCNATHAAYTCNGARAARGAYTGGAARTCN CARAGYCCNTCNAARCAYAARAAR------AARCAYAARCAYAARCAYAARAARAARAAR AARAARAARTCNAGYAARGARAAR---------------------GAYAARGARAARGAY ------------------------------------------------------------ ---------GAYGAYGAYGGNAARGAYGGNAARAARAAYAARGARAARGARAARAAYGGN AARAGYGAYAARGAYGARGAYTCNMGNACNGAYAARGAYAGYTCNTCNTCNAAYTAYAAR GAY------AARGCNAGYAARGCNAARGARAARAGYAGYGAYAAYGARAGYTCNGGNAAR AARACNGAYAARTCNGAYTCNAARAARMGNGAYAARAARAARMGNMGNCAYGAYMGNTCN MGNTCNMGNACNCCNAARAARTCNMGNMGNTCNMGNTCNCARTCNAARAGYCCNAARMGN TCNMGNAARAGYCARAGYCCNAARMGNCAYMGNTAYGAYGARTGGGAYGCNMGNMGNTAY AGYGAYGAYCAYAARMGNTCNAAR------GARMGNGAYMGNTCNAARGARMGNGAYMGN TCNAARGARGAYGGNGGNATHGAYYTNMGNYTNCARATHGAYAARGCNAARYTNMGNAAR ATHGCNATHGCNAAYACNYTNAAYACNATGAARTCNGGNCARCCNGTNCCNGTNCARYTN GAYGTNGCNGCNGTNAARTCNGGNGGNAARTCNGTNGARGARYTNACNGAYTTYTGYAAR MGNATHTCNGARAARGAYCAYGARMGNCARGARAAYGCNATHAGYGAYAGYAGYGARGAR GAR---CCNGCNCARAGYGARGAYGAYACNYTNATHCAYCAYCCNTTYAARGTNAARGAR GCNGGNGCNAAYATHGTNATGAAYATHMGNAAYGCNAARCARYTNCCNGTNYTNACNCCN TCNGARAARCARGCNCARCARGCNAAYYTNMGNYTNTCNTTYCCNGTNTCNAGYGGNACN CAYCAYMGNGCNAAYGARTCNGARTGGGTNCCNGTNGARAARACNACNGCNCCNGCNACN TCNACNACNACNATHGCNACNACNACNCARGCNTCNACNACNGCNAARCCN------GAR CCNTCNAAR---------AGYATHTTYCCNACNGTNGARAARAGYGTNGAYATHGGNTCN ATHATHTCNGARMGNYTNCARGCNGTNMGNAARYTNCARCARAAYCCNTAYGAYGTNCAR GCNYTNAGYTCNATGCAYAARGCNCARGARAARGCNAGYCARTGGGCNCARTCNAARTTY YTNCCNGGNCARTTYACNGGNAGYACNGGNGCNCARGTNATGTCNCARCARGARATHATH GGNGAYAARMGNMGNCARGCNTGGGTNAARAAR------------------------ACN CAR------------------------------TTYGGNTGGMGNCCN------------ ------------------------------------------------------------ ---------------------CARCARGCNGCNMGNGCNCCNYTNGCNCAYAARCAYCCN GTNTCNGCNYTNATGGAR---------TTYTGYAAYAARCAYCCN--------------- ---------------------------CCNTCN---TTYACNGTNGTNTCNGARAAYGGN CCNGCNCAYAARAARTGYTTYYTNTTYAARGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CARGCNGARGARYTNGGNTGY GARGGNAARGTNGARGARTCNCARGGNGTNATGAARYTNGTNGAYCARYTNAARGARGAR MGNCARGTNYTNGAR------ATG---CARATGGAYGAYGGN---GGNCCNATGATGAAR CARATGGARGTNTGYGARGTNTGYGGNGCNTTYYTNATHGTNGGNGAYGCNCCNCARMGN CARGAYGARCAYYTNATGGGNAARCARCAYGCNGGNTAYGCNCARGTNMGNAAYGARATH GARMGNMGNAARCARAARGCNMGNGARGARATHGARGCNMGNGARGCNAAYGARAAYCAR ATGMGNYTNGARMGNGARGGNMGNGARYTNGARMGNCARMGNGARMGNGARGARAARMGN ACNAARGAYMGNGAYGGNGAYMGNMGNAGYGARMGNGAYMGNGAYAARMGNMGNMGNTCN MGNAGYMGNGARMGN------GGNAARGAYMGNMGNMGNTCNMGNAGYMGNGAYMGNMGN MGNMGNMGNAGYTCNAGYMGNGAYMGNAARAGYMGNMGNAGYMGNAGYMGNGAYMGNGAR MGNAARMGN---------AGYTCNAGYMGNGGNAARAARTCNMGNMGNTCNTCNAGYMGN GARMGNMGNAGYAGYMGNMGNTCNAGYMGNGAYMGNAGYTCNMGNAGYAARGGNMGNTCN GGNTCNAARGARAARGTNGAR--------------------------------------- ---------------------------------------------------ACNATHACN AAYCARACNYTNGTNAARMGNTGYCCNCARGAYTTYATHCARYTNYTNTCNGARAGYYTN AAYGGNAARGARACNAAYAAYTGGMGNAARYTNATGGGNTAYACNGARTGGAAYTAYGAY AARATHACNAARTTYTCNAAYMGNAGYCAYGAYCARGGNTAYTTYTGYAGYATHYTNAAR GARCARAGYTTYCARCARTAYACNATHGARCARYTNAARGARGAYYTNGAYAARATHCCN MGNMGNGAYGTNYTNGCNGAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGGCNGCNGTNGARYTNGAY CCNATHTTYGTNAARGCNYTNAARYTNYTNCARTCNAARTCNAARGAYAGYGGNCCNCAR YTNAARGCNATGYTNGAYGAYGTNATHGCNCARMGNAARGGNYTNAARACNGTNTCNCAR GCNGGNGAYTTYGAYTCNAAR---TCNACNAARGGNAARGGNGAYGTNGAYYTNAARMGN AARGAYGCNGARAARMGNGTNYTNGAYAARGGNGCNAARGAYTCNTCNGARCCNGAYGTN AARAARTCNAARYTNGAY------------CARTCNTCNAARCARAARGARAARGAYAAY MGNGAYAARGARMGNGARMGNCARAARAARGARAARGARAARAARGAR------------ GARGCNCARMGNGARAARGAYMGNGCNGARAARGARMGNAARGARAARGARGARGCNTCN AARCAR---------GARGCNGARATHATHAGYGAYGAYGAYGARCCNGCNCARTCNATG GAYGCNGGNGAYTTYGCNMGNGAYYTNGGNATHAAYTGYGTNGTNTGYMGNCARTTYGAY GTNACNTCNGGNAAYCARYTNGTNGARTGYCARGARTGYCAYAGYYTNTAYCAYCARGAR TGYCAYAARCCNCCNGTNACNGGNCARGAYGTNAGYGAYCCNMGNTTYGTNTGGTAYTGY TCNMGNTGYACNAARTGYTTYAARAARATGATGGCNCARAARCCNGTNAAR---CCNGCN AARCCNAGYACNCCNYTNGCNTCNTCNATHAARGARTCNACNTCNTCNATHTCNAARAAY AAYAARATGGARTCNGAYTCNGGNAGYCARGCNTTYMGNMGNATHGAYCCNAARGCNATH GTNACNCCNAARGAY------------CCNGGNATGTCNAARGGNATGGTNGGNYTNGCN GGNYTNGCNGCNAAYYTNACNAARCCNMGNGGNGARTCNAARATGTCNTCNTCNYTNAAR AARTCNGARCAYAARAGYGAYACNTCNAARTCNATGGGNACNAARYTNGARACNATHAAR YTNGGNAGYAGYACNAARCARGARAGYGGN---------ACNAARCCNTCNYTNTCNTCN TCNAAYAARAAYGAYAGYMGNAARGCNGAYYTNACNACNAARTCNTCNTCNAAYAARGAR GARCARGCNAARGARGGNAAR------------AARTCNGAYGTNCCNAARCARAARTCN GAYGARAARAARCCNACNGAYAGYTCNTCNAARAARGARGAYAARAARGARAARTCNGAR TCNGGNAARTCNTCNTCNTCNTCNTCNTCNAARGAYGAYAARAARTCNGAYTCNMGNAGY AARTCNGGNYTNTCNCCNGGNAGYGCNTCNGCNGCNGAYCCNAAYTCNCCNATHAGYGGN GARTCNGGNACNAGYGGNGGNAGYAARAGYAGYAAYAARCARGCNATGGCNAAYYTNTCN ATGGTNACNGCNAAYAARMGNATHCARATGATGAARAARAARGCNCARACNAARCCNCAR GARAARATHGTNCAYATHAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYCAYGTNATHATHGGNGGNCCNGAYACNGCNAAYAAR ACNTCNTTYGTNTTYCARGCNGCNGTNTCNGCNGCNACNGCNGGNTCNAARGTNGTNCAY ATHTGYACNCAYCCNATHTCNAARYTNCCNACNCCNATHCAYGGNATGCCNATHCCNGAR CCNGCNGTNATGAARAAYGTNGAYTTYYTNTAYTTYGARGAYAGYACNGAYYTNATHGCN TAYTTYGCNGGNGTNCAYGTNAARAARAARYTNCCNAGYTAYATHATHGTNGARGAYATH YTNTCNTAYGCNTCNCARAARCARGAYAARCCNGTNGARAARAGYYTNGCNCAYYTNYTN GCNYTNATHGCNAAYTCNMGNAGYTGGATHGCNAGYCAYAAYGARACNGGNAARTGYCAR GTNYTNYTNACNGCNCCNTCNMGNATHAARTCNATGAARAAYGTNYTNTAYMGNTTYAAY TAYCARYTNGCNYTNTAYGARGGNCCNTCNAARGARAAYACNTTYTCNTGYATHTCNTTY CARGGNGCNACNGCNAGYACNTCNYTNACNTTYCARMGNCARAARAAYAGYYTNATGYTN CAYGAYGTNTCNGTNACN------------------------YTNATHCARATHAARACN GCNGAYGARAAYGARGTNTTYMGNMGNATHGARTCNTTYATHMGNAAYAARMGNAAYGAR GTNAAYGARMGNAAYATHMGNGARTTYATHTCNCCNACNGAYTCNGAY---GARAAYAGY TGYGCNMGNGTNGAYGCNGTNTAYATHCAYMGNGARGGNATGAARAGYCAYATHAAYYTN AARACNGTNGARAAYGCNTAYGGNCCNCARACNMGNYTNMGNCCNCAYTTYAAYAAYGAR GCNCARGCNTGGGARATGCCNGCNGAYGTNCARMGNGCNGARGCNYTNGARGARMGNATH GCNAAYATGGARTCNCAYYTNAAYATGTCNGGNGGNCCNAGYAGYATGCAYCARMGNATH AARGCNYTNGARGARMGNATHAAYTTYYTNGARGGNATHTCNCCNGARTAYTTYACNAAY GGNATHCCN---------------------------------------------TCNATH GTNCCNACNAARCARACNACNGTNGARATHGCNGGNCAYAAYACNGAYATHGTNGTNAAY AARTTYGAYGAYMGNYTNTTYATHATHGTNACNCARTAYCARAARATHGGNACNYTNATH GARGTNTCNMGNGAYGTNATHTCNGAYGARGTNCARGGNYTNATHCCNATGTTYTCNACN AAYGTNATHYTNGGNAARGAYGARCCNYTNACNCAYGTNATGGCNAARACNATHGTNACN GCNYTNAAYCCNCCNATHCCNGTNYTNYTNGGNYTNGCNYTNMGNGTNACNACNCAYGAR ACNGTNCARGCNATHATHCARCARATHAARTCNTGYYTNATGGCNACNAAYATGCAYTTY GARGCNMGNMGNMGNCARATGGTNYTNGAYAARGCNCARATHGCNAARGARAARATGGCN TTYGCNCAYCARTCNAAR---CARAAYGTNTTYYTNGAYGARCCNGCNTCNAARCCNGAR ACNATHGTNTGYACNGAYCARGGNCARTTYTAYCARACNMGN------------------ ------------------------------------------------------------ ------------------------------------------------------GCNGGN TAYAARGTNCCNCAYAARACNYTNATHTCNYTNGTNTTYMGNTTYGCNGAYGARMGNGGN CARATHAGYYTNGAYAAYTTYYTNGCNYTNATGGCNMGNYTNATGAARACNTTYAGYACN TTYCARAAYTCNCARMGNGAYGGNGTNGCNTCNTTYTCNYTNGAYCARTGGYTNGAYMGN TGYYTN------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGCCNAAR TTYTAYGARGAYGTNGAYGAYCCNAAYACNAARCCNMGNMGNGCNTGYGARGAYATHMGN GAYGAYYTNYTNGARTGYYTNYTNAARAGYGAYTGYTGYMGNAARGARAARAARACNCCN MGNGARTGYATGGGNMGNGTNGGN---------GAYGCNTCNGTNCCNGAYGARTGYTAY AARYTNMGNGTNGCNTTYTTYGARTGYMGNMGNTCNATGYTNGAYATGMGNACNMGNTTY MGNGGNMGNAARGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGCCNAAYACNGTNAARGGNGAYAGYAGYGGNGGNYTNTCNAGYGGNGAR GGNGCNGCNATHGGNATHYTNGTNATHATHTGYATHGTNGGNGCNGGNGTNGGNGTNTTY GTNTGYTAYMGNAGYAAYAAYATGACNACNMGNAGYTTYMGNGARTTYYTNTCNGGNGGN GTNMGNTAYAARACNTAYACNAAYGCNACNTAYAARGAYGAYGARGTNGTNATGGGNAAY ---GAYAARTCNAAYAARAAYGCNGTNCARGCNAARATHAAYMGNGARAARAARAARGCN TAYATHAARAGYYTNGARGAYGARATHAARGCNYTNMGNGCNGAYAAYGARAAYYTNAAR TCNGARAAYACNGCNATGAARAGYMGNGTNGGNGGNYTNGARCARGARACNGARTAYYTN AARTCNGTNYTNGTNAAYTCNAGYTCNYTNTCNGGNYTNYTNAARAAYATHTCNAAYGTN AARGARGTNAARYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNTTYGTNGCNGCNCAYGCNGGNGCNGGNAAYCAYTCN AARAARAGYGARGCNCAYGTNMGNTGYYTNTGYAARATGGCNTGYCARCARGCNGTNTAY ATGGTNACNGCNAARAARAGYGCNATHGARGCNGCNACNGCNGCNATHATGACNYTNGAR GAYGAYGARAARACNAAYGCNGGNTTYGGNTCNAGYATGACNGARACNGGNGAYATHGAR TGYGARGCNAGYATGATGGAYGGNMGNACNYTNMGNTTYGGNGCNGTNGCNGCNYTNTCN GGNGTNAARAAYGCNATHCARGCNGCNAGYYTNYTNATHACNGAYCARGAYAARGGNCCN YTNCCNTTYGGNMGNGTNMGNCCNAGYATHYTNGTNGGNAARGGNGCNAARTCNTTYTGY CAYGARCAYGGNATHGAYACNAAYTAYAAYCAYATHTCNAARGCNGCNTTYAARACNTAY ACNMGNTAYAARMGNAARTGYCARYTNACN---TCNTCNGAYGCNTCNAGYGARAARMGN MGN--------------------------------------------------------- ------------GGNTCNATHGTNGARAARTCNGAYGAR---------AARYTNTCNAAY TCNATHCAYGAYACNGTNGGNGTNATHTGYATHGAYGARGARGGNAAYATHGTNGCNGGN TCNTCNAGYGGNGGNATHTGGYTNAARCAYCCNGGNMGNGTNGGNTCNGCNTCNGTNTAY GGNGCNGGNTGYTGGGCNCARAAYCARACNGARTAYGGNGARCCNGGNGTNGCNGTNYTN ACNTCNGGNTGYGGNGARCARATHATHCCNACNYTNYTNGCNAARACNTGYGCNGARGGN ATHCARCAYTCNGAYCAYACNGAYCARACNYTNTCNGARGTNTTYAARAGYGARTTYYTN GAYTCNAARTTYYTNACNCAYCARCCNGARAARATGGGNGGNGTNYTNGCNGTNAARTAY ACNGAYTTYCCNGARGGNMGNAARGTNGARGTNTCNTGGGCNCAYTCNACNCAYTCNTTY TGYATHGCNTTYATHGGNGGNGAYCARTCNTAYGCNCARGGNYTNATGTCNMGNATGGAY TCNGAYAGYACNTTYGGNAARTCNGTNATGGTNGGNTGYCAYGTNCAYTAYYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AGYACNAAYCCNYTNGTNMGNGCNATHATHACNACNGCNACNGGNATHATHTTY GGNATHGCNYTNGARAARGGNMGNGTNTTYGARCCNCARGTNATHMGNGAYCARATGYTN TTYAARMGNTTYGGNATGATHAARATGTTYYTNTCNGCNTCNGCNATHGGNATGGTNTGY TTYTCNYTNYTNAGYGTNYTNCCNCARACNATGMGNAARTTYGGNYTNACNGTNCARAAY TAYCCNGAYGGNTCNGGNYTNAARTCNGTNTTYGGNGTNGTNACNGGNGCNGCNATGYTN GGNGCNGGNYTNACNATHGCNGGNGCNTGYCCNGGNACNATHTTYGTNCARYTNGGNACN GGNGTNCCNAAYGCNTGGYTNACNGTNYTNGGNGGNYTNTGYGGNGCNATGYTNTAYGCN TTYACNAAYYTNTCNYTNCCN---TCNATHTTYTTYAARGARAAYMGNAAYCCNAARTCN ATGAAYGAYYTNYTNAARGTNTCNTAYYTNCARATHGCNATHCCNATGTCNTGYGTNATG GCNTTYACNGTNYTNGGNATHGARTAYTTYACNCCNTGGGARACNGARGTNCARGARTCN YTNYTNACNGGNGGNATGATGATGGCNGGNGCNTGGCCNCCNTTYATHGCNGGNATGATH ATHGGNTCNYTNCARATHCCNACNGTNYTNGCNAAYGARGAYGGNYTNGGNTCNGCNMGN AGYTAYGTNACNGTNGCNTCNCARYTNGTNCCNACNAGYYTN---------GTNAAYMGN TCNAGYCARTAYTTYAAYTTYTTYAARGCNGGNATHTCNAAYTGGTGGCARGTNYTNCAY GTNTGYTCNGCNGTNYTNGGNGGNTTYATHTCNTCNATGGCNTCNGGNACNTTYMGNACN GTNCCNGGNGTNACNGARGTNCARGCNTTYGGNGGNGGNATGYTNATGGTNTTYGGNTCN MGNYTNGCNGGNGGNTGYACNAGYGGNCAYGGNYTNACNGGNTTYGGNYTNYTNTAYYTN ACNTCNTTYGCNGCNGTNCCNGCNATHTTYGGNAGYGGNATHYTNACNGCNTTYTTYATG AARGAYGTNYTNGGNATHGARYTNATGAARGAYGARYTNTCNYTNGTNATHTCNGARYTN GARGGNGTNAARACNGCNGCNGCNGTNTCNGARAAYAAYAARCARCARGARATHAGYAGY GCNATHACNAAYTAYCARCARGARGTNGCNACNYTNCARGARYTNYTNAARGAYGTNGCN GAYACNGCNTCNGAYAAYACNGCNGCNMGNTAYGARTCNGARMGNACNAARYTNGTNTCN YTNAAYGARAAYTAYGARGARGARATHCARGARYTNMGNACNAARYTNACNCARGARMGN GARNNNTTYYTNTCNTCNGTNGCNAARTCNATHAARTGGGTNGGNAAYGTNGGNAGYAGY GCNTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGNCCNGAYAARGAYYTNCCNTCNGGNATGYTNCCNTCN CARCCNACNTCNCARATHTCNGGNTTYAAYGGNGGNACNAAYTTYTAYGGNCARGGNAAY YTNTCNYTNCARCAYMGNGCNATHGGNGCNAAYCAYTTYMGNGGNGCNAAYAAYACNGGN CAYATHACNCCNACNAGYATHAAYCCNGGNTTYCCNYTNGGNYTNCARCAR---CARCAR CARCCNCARCARCARCARCARCAYTCNCCNAAYAGYYTNGCNGCNATHGGNTCNMGNAAY GTNATHGGNGTNCARAAYCARGGNGGNCARCARAAYYTNGTNAAYYTNCARAARMGNCCN TTYAGYTCNGCNGCNCCNATGCCNAGYTTYGCNTCNACNTAYGGNTTYGGNGGNGCNGGN TCNATH------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AGYGARTAYMGNGGNMGNGGNGGNGGNMGN GGNMGNGGNGARTAYMGNGGNMGNGGN---GGNGGNTAYMGNGGNGGNMGNGGNGGNTAY GAYGGNGAYMGNGGNAGYGGNMGNGGNGGNTAY---MGNGGNMGNGGNGGNTTYTCNMGN GGNMGNGGNGGNCCNCCN---AGYMGNGAYGAYTAYTCNCCNCCNMGN------ATGTCN MGNGGNTAYGAYGAYACNGAYMGNGGNMGNGGNCCNCCNGCNGARMGNMGN---GAYMGN TTYGARGAYAGYTTYGAYMGNGGNAGYACNTCNYTNMGN------------TAYTCNTCN CCNYTNMGNGAYACNGGNMGNAGYTTYGAYMGNCAYTCNTCNCCNCCNCCNCCNMGNMGN GAYMGNGAYTTYGCNCCN---MGNCAYAGYGAY---------------MGNGAYTTYGCN ATHTCNTCNMGNTTYTCNCCNCCNMGNGAYACNGGNTAYGCNTCNTCNTAYAARGARTCN TAYACNTCNACNMGNMGNGARGAYMGNMGNCCNCCNMGNGAYTAYGCNCCNMGN------ ------------TCNACNGAYTAY---GARMGNMGNGAYTTYMGNGAYGCNCCNAAR--- GAYTAY------AGYTCNMGNGAYTAYGTNCCN---TCNAGYMGNAAYGGNGAYTAY--- ---------------------------------------MGNGAYTCNYTNAGYAGYMGN GAYTAYTCNTCNMGNGGNGGNGAYMGNTAYAGYAGYGGNGGNMGNGGNMGNCCNAGYTAY GAYGAYMGNGAYTAYGGNGGNMGNGGNMGNGGNAGYMGNGAYGAYMGNGGNTCNAGYMGN GGNATGAAYGGNTCNMGNGGNMGNGGNGCNCCNMGNGGN------MGNGGNMGN---GAY TAYTCNGGNGGNMGNGGNCCNGGNGGNAARMGNCCNMGNATG------GARTCNGGNGAY TAY---------MGNMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ACNAGYGAYGGNGAYCAYATGTTYYTNGARACNTGGGAYYTNAGY TTYAGYYTNAGYAGYYTNGAYATHTCNGCNTGYAARGTNCARCAYATHTAYACNMGNATG GGNYTNTGYYTNAARTCNYTNYTNTCNGCNACNMGNGCNATHCCNGGNTAYMGNYTNTCN AARAAYCARGGNGARAARGGNGGNGGNTAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR GCNCARAAYAARGTNAARMGNTTYGGNATHYTNGCNAARATHYTNGARYTNGTNCCNYTN ACNAARTCNGTNGCNACNATHAARCARATHATHACNGCNTAYACNMGNMGNYTNYTNTGY YTNYTNGARGARAARAAYGTNYTNGARGAYCARGARYTNTCNCARGARYTNYTNAARTGY GTNAARACNTTYTGGTCNYTNTGYTAYAGYCARCARTCNATHCARTCNGGNTCNCARTTY GGN---MGNTGGGAYGGNTCNYTNATHGARGTNGTNACNTCNYTNGCNTCNGTNTTYGTN GAYYTNTTYATHACNGCNAAYGGNTCNAARGARAAYCARTCNYTN------TGGTCNAAR MGNYTNTAYAGYTGGYTNAAYTAYGAYYTNCCNGTNMGNGCNATHAARGTNGCNYTNYTN GARGTNACNGGNCAYAARMGNGAYGGNGCNGARGTNGCNGGNCCNYTNATHAGYMGNYTN ATHCARATGAARTTYGAYTCNGAYTCNAAYCCNGARTAYYTNYTNCAYTTYYTNATHTTY AARAARTGGCARCAYYTN---GCNGAYGTNACNACNATGGARACNGTNTGYACNTCNYTN AARGCNCCNTCNCARTTYATHCCNTGGYTNAARACNTAYTGGAARTCNGCNAGYGARTAY ATHCCNGAYGAYAARAGYYTNAARGGNTCNAARGTNAGYCARTTYYTNYTNGAYYTNGAY ACNGAYGAYGTNYTNGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CCNTTYTCNAGYYTNAAYACNACNTTYCCN GCNGGNCCNATHTTYCARGAYTCNCCNCARCARATHCARYTNAAYGTNCCNACNGTNACN TCNCAYGAYGGNAARTTYCARYTNACNATGCCNATHGAYGAYTTYAARCCNGARGARYTN ACNGTNAARACNCARGAYMGNAARATHATHATHTGYGCNAARMGNGARGTNACNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARTTYACNGAYGAYGARATH MGNCAYGARYTNGCNYTNYTNGGNTAYCAYAAYGTNCCNCAYGAYAARYTNGARGAYTTY AARMGNGAYYTNATGCARYTNATHTGYAARGARMGNAGYMGNTCNAAYTCNYTNAAYAGY AGY---------------------------MGNGTNACNGARACNGARGGNGARGARGAR AARYTNAAYYTNGARACNGGNAGYACNAAYAAYCARGCNAGYCARGCNAAR---GARAAR ACNTTYAAYGARAAYTGGTAYTAYCARGGNGAYGARAGYCCNACNTAYTCNMGNMGNAAY GAYTAY------------------------------------------------------ ------------------TAYAAYYTNCCNTCNTCNMGNTCNYTNACNTCNCAYCCNMGN GAR---------------------MGNAAYCARAGYAAYTGYGTNCCNGAYGAYATHGAR GCNAGYTCNGAYAGYMGNTCNATGAARMGNAARACNTCNMGNAARGCNCCNGAYGGNTGY CARATGATHGAYGARTCNTTYTCNGAYTCNAAYGCNGGNYTNTTYGARATHTAYGARMGN ATHMGNAAYYTNGCNATGMGNGARTGYGARTGYGTNAARAGY------GGNAARAGYGAY TCNGARCCNCCNTAYMGNATHCAYGGN---AARAAYAARAAYCCNTCNYTNATHMGNAAR AARGARCCNCCNCAYACNMGNAAYYTNATHMGNACNAAYATHAAYGARMGNCAYAARATG TAYAAYGAYGTNTGGAARGCNCARCCNCCNGTNGGNGARGAYMGNMGNYTNAARYTNMGN AARACNGTNCAYGCNAARATGATGAARCAYCARGAYATHAARYTNAARCARAARATHTAY GTNCCNAAYTCNTAYGTNCCNCCNCAYGARAARYTNMGNAARGAYGTNMGNTGGCARGTN AARCARGCNTTYGARAAYTAYGARYTNCCNGARACNGGNTTYTAYCAYGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR YTNTCNGTNGTNAARMGNCARGTNGCNYTNTTYATGGARGAYTTYAARAARGARCAYGAY GARMGNGTNTCNATHGARAARAARTGGAARAARGAYAARGARACNAAYCAYAGY------ ------YTNGARAAYAARYTNAARMGNACNCAYGAYYTNYTNAARTCNMGNGAYGARGAY YTNMGNYTNAARTCNAARTCNGTNGCNGAYYTNCARTAYCARGTNGAYGAYYTNAARYTN AARYTNGARGTNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNACNAAY GARGARTAYAARTGYCCNTCNMGNYTNACNCARAARTTYTCNGARATGATHATHGTNGAY CARCARATHAAYAARTAYGAYTAYCAYYTNCCNYTNTCNTCNCCNGTNACNATGTCNATH ATHGAYCCNAARCAYTCNAAY------ACNTCNGARATHGARGARCCNGCNCCNCCNCAR ------CARTCNAAYGCNAARGARGCNAARGARATHATGMGNATHMGNCAYAARAARATG AARAARCAYAARYTNAARAARYTNMGNAARMGNATGTAYTTYGTNTGGAARAARCARAAR YTNACNMGNMGNGCNAARMGNGAYGCNATHTAYTGGAARGGNATHTCNGAYATHAARAAR GAYGGNGAYGAYTTYGAYGCNGARAGYTTYGTNAAYGAYCARYTNAAYAARGCNMGNMGN GGNGGNTAYTAYGTNAAYGTNTTYGARTCNAARATHTAYGGNCARGCNGCNCARAARTGY ACNTCNCARGGNGGNTAYYTNGTNGARATHAARAAYCCNGAYGTNGARMGNGARYTNMGN CARACNATHAAYTAYGTNTTYTGGATHGGNGTNMGNGAYCCNAAYAARGAYMGNAARTGG AAYTTYTTYAAYGGNGARCCNGTNAGYAARTAYACNGCNTGGGCNAARGGNGARCCNAAY AAYGTNAARMGNMGNGARTAYTGYGTNGARATHTGGCCNGCNAARTGGAARYTNTAYTGG AAYGAYGARGCNTGYGAYYTNMGNMGNGARTAYATHTGYCAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARGTNATGAAY YTNYTNAARGGNGTNTTYGTNYTNATHATHGCNGCNATHATHYTNCAYTGYGTNGCNGTN YTNTTYGGNGCNCCNGTNTAYACNTCNGTNCARGARACNTTYCAYTTYGCNGTNYTNYTN ACNACNYTNGTNGTNYTNCCNTGYTAYGCNGTNGTNGGNACNAARTTYGAYAARYTNATG AAYATHTTYACNTTYGAR---MGNGARCCNGGNYTNGARACNGTNGTNTAYYTNACNTCN YTNGGNGCNATHATHGGNGCNTGGYTNGGNGCNGTNCCNATHCCNYTNGAYTGGGAYMGN CCNTGGCARACNTGGCCNGTNAGYTGYTCNATHGGNTCNATHGGNGGNTAYTCNYTNGGN YTNTTYYTNTCNTCNATHTAYATHCCNCAYGARTAYAARGCNGCNGTNAARAAYAAR--- ------------------------------------------GARGAYTTYATGATGGAR YTNTAYAARAAYTCNGGNTAYMGNATHCCNGTNTGGGCNATGGGNCAYGCNGGNCAYTCN CARGCNCCNTAYCARACNYTNACNYTNCARGAYGTNTAYGCNACNGAYGARAARAARTAY GGNYTNYTNGCNCARATHCARCAYAARGTNACNTTYGTNAARGARTAYGTNCCNCCNGAY GTNAARYTNATHYTNATHGGNCAYTCNATHGGNTGYTAYTTYATHYTNAAYGCNYTNGAR AARYTNTCNCCNMGNTCNGTNCAYCAYTGYTTYTTYYTNTTYCCNACNATHGARMGNATG GCNATHTCNCCNAAYGGNGTNACNCAYACNCCNATGYTNMGNTAYTTYMGNTGGATHGTN GTNTTYATHGCNTTYYTNTGYGTNGTNYTNCCNACNAARATHMGNGARATGATHATHTCN TTYYTNTAYMGNAARACNGAYCAYCCNGARTGYATGGARCCNGCNATHYTNAARATGGCN ACNCCNTGGACNGCNAAYTTYTCNACNTTYYTNGCNAARACNGARATGAAYGGNGTNACN GARYTNCARAARGAYYTNGTNGGNAARCAYYTNGAYAARYTNAGYTTYTAYTAYGGNTGY TGYGAYYTNTGGACNCCNMGNCAYTAYTAYAARGARATHATHGARYTNTTYCCNACNYTN GAYGCNMGNATGTGYCARYTNAAYATGAARCAYGCNTTYGTNATGATGMGNCARGARGGN CAYCARATGGCNAGYGTNYTNTGGGAYTGG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARCAYTAYTCNYTNYTNTCNCAYTAYGARTGGYTNCAY AAYTTYCCNGTNACNGARATHTTYAARAARAAYATHATHAAYCARATHGAYCAYCARTGG TAYTCNTGYYTNTGYAAYYTNAAYGTNGAYGAYYTNAAYATHGTNCCNTTYATHGARGAY GAYAAYAARTCNAARTAYCCNGAYTGGCCNGAYACNYTNCAYGARTTYGTNAARAARTCN AAYCAYYTNTCNATHCCNMGNAAYATGGAYGARACNGTNAARCCNGTNGAYATHAGYCCN GARATGGCNMGNGGNATGAARAGYAARAARYTNCAYGARGTNTCNMGNATGGCNTCNYTN GTNTCNAAYATHGCNAAYGARGCNAAYTGYGAYATHGTNATHGAYGTNGGNTCNGGNYTN GGNTAYYTNGAYCAYGTNYTNCAYCARGTNTAYGGNYTNAAYGTNYTNGGNYTNGARACN GTNTAYAGYCAYGCNTCNGCNGCNGARAAYMGNGCNGTNAGYCARGGNATHATHTGYGGN GGNATHAARAGYATGCARTGYCAYATHGAYGAYAAYGARGAYTCNTAYACNAAYTTYATH MGNAGYGTNGARGGNGTNYTNCCNAGYYTNMGNTGYGARTGYAARAARAAYYTNGAYCAR GGNACNAAYGTNGARGGNAGYCCNMGNGTNTGYYTNATHGGNYTNCAYTGYTGYGGNGAY YTNTCNACNACNATGATGTCNTAYTTYAAYTCNTGYTCNTTYATHAARGCNATHTGYTGY GTNTGYTGYTGYTAYCAYAARATGGTNTAYTCNAAYGAYAGYTTYACNAARTTYCCNYTN AGYTCNATHGGNAARGARTGYTAYCARCARTGYGTNGARAARCAYGGNTCNCCNTTYATH ACNCCNTTYACNYTNMGNYTNGGNGCNCARGGNACNMGNCARMGNTGGCARCARCARTCN AARGCNGAYCAYCARTGYCAYACNAAYCAYGTNGGNTTYMGNGGNATHYTNAGYTTYACN GAYGARAGYGAYGCNGARATHMGNCARAARGTNMGNCARTGYAAYTTYGARTCNATHGAY AGYTTYTCNGARTCNTTYTAYAARGGNCCNTCNCARGCNGAYAARMGN------------ TCNGAYYTNATHTCNGTNTAYGARAARTAYAARACNCARTTYGAYGGNATHGARGTNYTN ACNYTNYTNCARGTNATHYTNCARCCNGTNATHGARACNYTNATHTAYCARGAYMGNTGY ACNTGGYTNAARGARCARGGNCAYACNGAYGTNMGNAGYATHCCNATHTTYGAYGARTTY ATHTCNCCNMGNAAYYTNGCNATHATHGCNACNAARTCN---TGYCARCARTGYGTNCAR AGYTTYTCNAARTCNAAYAAYAGYGAYYTNAAYMGNYTNGTNTTYGARGCNATHAGYAAY CARYTNMGNTCNGCNGCNAARAAYATGACNGARAARYTNGAYYTNATHTCNGARATGTTY TCNAARCARTGYAAYGTNATHYTNGCNCARMGNATHMGNMGNTCNTAYCARATHYTNYTN YTNTAYMGNAAYYTNTAYGGNGARMGNYTNYTNAARGARAARGTNAGYACNCARATHAAY MGNATHAARAARAARCCNYTNATHGCNGTNYTNTCNGCNACNGTNTTYAAYTGGGAYMGN GARMGNATHTCNGAYGARGARGTNAARMGNTGYTAYAARGARGTNGAYGARGTNCAYMGN YTNAAYGTNGGNTCNGTNYTNAARCARGGNAAYTCNACNACNGTNACN------------ ---------------------------AAYTCNAARGGNAARTGGGARCARGTNGTNAAY AARGARGAYTTYAARGTNTGGMGNCAYCARYTNCCNAAYTCNGARYTNTAYCARTAYMGN GTNYTNGGNCARTTYAARGAYYTNCCNGCNMGNGCNTTYTAYAAYACNCARGTNGAYGTN CAYTAYTGGAARGAYTGGGAYGCNCARACNATGGAYGTNMGNGTNGTNGAYAARGAYGCN ACNTCNGGNACNGARGTNATHCAYTGGYTNTAYTCNTTYCCNTAYCCNATGTAYCCNMGN GARTAYGTNTAYGTNMGNMGNTGYATGGTNTAYCCNGARAARAAYTGYATGATHATHACN GCNAARGCNACNAARCAYCCNAARTGYCCNCCNAAYAARACNTCNGTNMGNATHGARAGY TAYMGNTCNCARATGATHATHACNCCNAARAAYGGNTTYGAYGARAAYGGNTTYACNTAY GTNATGTCNTAYTAYGAYGAYCCNCARACNAAYTTYCCNCCNATGTGGTAYAAYTGGGTN GCNAGYGCNGGNGTNCAYGARTTYYTNCARMGNYTNCAYGGNGCNGCNYTNAARAARCAY ------------------------------------------------------------ ---------------ATGYTNYTNMGNYTNAARGARGTNATHCARTGGACNMGNATGACN GCNYTNGARYTNATGYTNCAYYTNATHTCNTTYYTNGTNTTYTCNATHYTNYTNGCNGCN ACNGTNGARGGNGTNATHAGYGTNTCNTGGCCNGCNGTNTTYTCNCCNYTNTTYATHTGY GAYGGNYTNAAYACNTAYYTNTGYGTNATHATHTTYGTNMGNCARTAYMGNGARTAYGAR YTNAARCARGCNATHTTYMGNYTNTCNAAYTCNYTNTGYGTNATHGCNYTNATHTTYACN TTYAARYTNYTNYTNTGYCARAARYTNCARAAYGCNGGNYTNTCNTGYTCNCARGCNTTY AGYCCNGTNTTYGTNYTNTCNCCNGTNTTYATGTTYMGNGCNTGYMGNATGCAY------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGCNGAYMGNGTN GARCCNCCNCCNTTYGARAAYGAYGARGAYGARGTNAARGAYGARGAYGAYYTNTTYGCN GAYGCNAARGARAARACNTCNTCNCARGAYACNAGYCCN------GCNGARTCNGTNAAY GGNACNGCNCCNGAYGCNYTN---GARAARGAYGAYGAYGARGAYGAYYTNTTYAARGGN GGNAGYTCNGARATHAARYTNGARTCNGAYGARGARGARGTNCCNGCNGTNAAYAAYAAY GCNGCNAARGARGAR---------------------------------CCNCCNGTNGCN GCNGCNGCNCCNACNCCN---AARGARGTNACNCCNGARATHTCNGTNTCNGARGTNATH ACNGCNAARACNAARATHGCNGCNCCNTCNYTNAARACNGAYGARTTYTCNGAYGAYAAY ---GARGARAARGARCARTAYGAYYTNGARATHMGNATHACNGARAAYYTNAARATGGGN GAYGGNATGTCNGCNTAYATGGTNTTYAARATHGTNTCNAARACNTCNAAYCCNGCNTAY MGNACNTCNGARAAYACNGTNYTNMGNMGNTTYAGYGAYTTYYTNGGNYTNTAYTCNAAR YTNGCNGARAARCAYGTNCCNYTNGGNATHATHGTNCCNCCNGCNCCNGARAARAGYYTN GTNGGNATGACNAARGTNAARATGTCNAARGARGAYACNGGNTCNATHGAYTTYATHGAR MGNMGNAARGCNGCNYTNGARMGNTTYYTNATHMGNACNTCNGCNCAYCCNGTNYTNGCN GCNGAYCCNGAYTTYATHGARTTYYTNGARAARGAYGGNGAYYTNCCNAARGCNACNAAY ACNTCNGCNYTNAGYGGNGCNGGNGTNATGMGNYTNTTYCAYAARGTNGGNGARTCNYTN GARAARATHACNYTNAARGTNGAYGARAGYGAYGARTGGTTYGARGARAARCAYCARCAR GTNGARGCNYTNGAYAGYCARYTNAARAARYTNCAYATHAGYYTNGARACNYTNGCNGCN CAYMGNMGNGARYTNTCNGGNACNACNGCNATHTTYGCNAARAGYGCNGCNATGYTNGGN AAYGTNGARGARCAYACNGCNYTNTCNMGNGCNYTNTCNCARYTNGCNGARACNGARGAR AARATHGARYTNGTNCAYAARGAYCARGCNGARGTNGAYTTYTAYACNATGTCNGARYTN ATGAARGAYTAYGTNGCNYTNATGGGNGCNGTNAARGGNGCNTTYCAYGARMGNATHAAR GTNTAYAARAAYTGGAARGAYAGYGARACNATGYTNGGNAARAARMGNGARAAYAARGCN AARYTNGARATHGCNGGNAARTCNGAYAARYTNCCNCARGCNMGNGCNGARATHACNGAY TGGGARCARAARGTNGARAARGGNCARGARGAYTTYGARAARATHTCNAARACNATHMGN AARGARGTNGCNMGNTTYGARAARYTNMGNGTNGCNGAYTTYAARACNAGYGTNATHAAR TAYYTNGARGTNYTNATGGARAAYCARGARAARYTNATHAARTAYTGGGARACNTTYYTN CCNGARGCNCARGCNATHGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARTGYCCNCAYGARGGNTGYGGNAARAGYTTYMGNTTYCCNTTYACNYTNMGNAARCAY ATGAARTCNCAYGAYGGNTAYAARTGY------GARYTNTGYGARACNGTNGTNGARACN TGGACNCARYTNMGNAARCAYAARAAYGARATHCAYCCNCCNGAYYTNAARTGYTAYACN TGYMGNATGGARTTYAARTCNAARGCNAGYYTNAARTCNCAYYTNCARAAYCAYTTYAGY MGNGTNGAYCCNTTYATHTGYCCNMGNGAYGGNTGYACNMGNTCNTTYAARTAYAARAAR AAYATGAAYCARCAYATHMGNGCNTTYCAYGAYGGNGAR---------------MGNGTN TTYCCNTCNAARGCNAARAARGTNTCNGTNGCNGGNMGNGARTCNMGNAARATHAGYCCN GCNGCNMGNYTNGCNGGNATHGAYGAYMGNAAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNGCNGTNGAYMGNGCNGGNGTNACNGAR------ACNGCNATHGGNAAY AAYACNGGNAAYCARACNCCNCCNCCNGGNTAYCAR------------------------ TCNGGNGCNYTNGCNCCNYTNCCNGCNCCNGTNCCNCCNCARTCNMGNTGGGCNMGNGTN MGNGAYYTNACNTTYACNTCNGTNGTNGTNGTNGGNGTNTCNTAYGGNATGTAYCARYTN TTYAARACNTTYATHATGCCNYTNATHACNGGNTCNAARCARCARGARAARMGNATHGAY MGNYTNGARACNCARATHGCNGARATHCAYAARTCNGTNAAYGARTCNYTNACNGARATH AGYMGNACNYTNGCNGCNATHCARYTNAGYATHAAYACNCAR------------------ ------------------------------------------------------------ ------------------------------------------------ATHTCNGCNAAR ATHGCNMGNTGGTGGMGNCARMGNMGNATGCARGGNYTNATHGCNGARYTNCCNAARTGY AAYCCNAARTCNATGYTNTAYCAYATHTCNMGNYTNCCNGARTGYMGNAGYTTYYTNCAR AARGARAARMGNMGNYTNYTNCAYYTNYTNCARACN---GGNTGYAARGARGTNAAYGTN TTYGTNTCNYTNGCNAGYYTNGARGAYTAYGTNGGNAAYTTYTCNTCNAGYYTNGAYTAY ATHCARCARGCNATGAARATHGAYCCNACNGGNAARGAYYTNYTNTGGYTNAARGARAAR GTNTCNAARCARTGYGARACNYTNCARCARCARACNGAYGCNATHGARMGNYTNAAYAGY GAYAARYTNAGYTTYCCNCARATHMGNCARGTNCCNMGNGTNTCNGGNAGYGARYTNAGY GTNTCNGARTTYAARGARCARTAYYTNACNGCNGGNAARCCNGTNATHGTNACNGAYGTN GTNGGNAAYATGACNAARACNCCNTTYGAYTAYTCNATGGTNGTNGAYCAYGCNGGNAAR ACNGTNGTNTCNACNAARCARACNATHAARGAYTCNACNACNTGGGCNAARYTNGARAAY AAYMGNGARATHACNGTNGGNGARATGATHCARGAYATHCARGAYGGNTGYGCNMGNGAY TGYYTNTTYGAYTGGAGYYTNCCNYTNCAYTGYCCNAGYYTNAAYCARYTNATHACNYTN CCNGARTAYTTYAARGAYAAYTTYYTNYTNCARACNTCNCCNGGNTCNYTNTAYMGNCAY AGYTGGCCNAGYYTNTTYATHGCNCCNAARGGNGCNATHACNCARYTNCAYGTNGAYGCN TTYCAYTCNCAYTTYTGGATGGCNYTNTTYCARGGNCARAARAARTGGACNTTYTTYGAY GARYTNGAYACNTCNYTNYTNTAYCCNCARAGYTTYCARTCNATGGAYCCNGTNTTYACN GTNGAYYTNACNCARCCNGAYYTNGAYMGNTTYCCNYTNYTNTCNYTNACNACNCCNCAR CARTGYGTNYTNCARCCNGGNGARYTNYTNTTYGTNCCNGCNGGNAGYCCNCAYATGGTN GARAAYYTNACNAAYACNYTNGCNATHTCNTCNAAYTAYGTNGAYCARTCNAAYTTYGAR AARGTNTGYCAYCARYTNCARATHAAYTCNYTNCARGAYGARMGNGCNGCNGAYYTNYTN TCNCARYTNGARGAYCCNMGNTTYYTNAARMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARAAYCCNTAYTAYGGNTCNMGNAARCCNAARTCNCARATG MGNTCNGCNYTNCAYAAYGTNAGYGAYYTNTTYGTNATGGGNGGNGCNYTNATGYTNGAR TCNYTNGCNYTNYTNCAYTGGTGYGARMGNCARGGNTGGGGNCCNTTYGGNYTNTCNGGN GTNTCNATGGGNGGNCAYATGGCNTCNYTNGCNGCNACNAAYTGGGARAARCCNATHTCN YTNGTNCCNYTNYTNTCNTGGAGYACNGCNTCNTGYGTNTTYACNCARGGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARAAYACNTTYTGYAARTAYAGYCAYMGNGAYTGYACNCARAAYTGYYTNGAR GGNTAYGAYTAYTGYYTNMGNCAYATHYTNGARGARAARACNGCNCCNTAYMGNCCNTGY GCNTAYGTNACNAARGCNGGNMGNAARTGYACNGCNGCNGCNCCNAARYTNGAYAARAAR GARTGYTTYTGYGCNTCNCAYACNAARAARGCNYTNYTNATGMGNCARMGNTTYACNMGN AARMGNMGNCCNAARGARACNTCNGAYACNYTNYTNGARGAYYTNGTNGCNACNACNTTY TCNYTNGAYTCNAAYCAYTCNGTNGARCAYMGNMGNGGNAARATHCAYAGYGAYAGYGTN GCNGCNAARTCNYTNGARTAYGCNAGYTCNAGYGAYTCNGAYACNGARTCNATGCARGTN GARCAYGCNTGGMGNGAYTCNGGNGAYAGYGAYGCNGAYAGYATHGAYAGYGAYCARGAR GAYATHYTNAARTAYGCNGGNGTNTAYACNACNGARGARGTNGCNCARATHYTNMGNGAY AARYTNATHMGNYTNCARGCNYTNTAYATHGAYCARTTYAARMGNYTNAARCAYATHYTN YTNACNAARMGNAARCARTTYYTNGARGARCARAARTTYGARAAYMGNYTNTGYGGNAGY ATHAARMGNTAYAARCARGAYCCNCARCARMGNGARYTNTAYGAYAARYTNTGYGCNATG AARMGNTAYCAYAARAARTTYGGNATGGARAAYYTNATGCARCARCARTCNATHCARMGN MGNYTNAARATHACNGARGGNATGGCNGAYAARYTNTCNACNCCNATHAARTGYACNTTY ACNGAYGARGGNYTNGGNTGYACNCARCCNGTNGTNCCNYTNAGYAARTTYTGYCARAAR CAYATHYTNCAYGAYCARCAYCARGTNYTNTAYCARCCNTGYCCNTTYGCNGAYAGYCAR TGYGGNMGNCCNGTNGCNACNYTNYTNGGNAGYCCNTTYTGYTCNYTNCAYCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATHTCNGAYTTYAARGTNTCNAAYMGNGAYYTNGTNAARGAYATGGARGGNTGYCARCAR MGNGARTCNAARATGYTNGGNYTNCARTCNGARYTNAGYMGNAGYAAYGCNTGYYTNMGN TCNGARAAYACNACNYTNAAYAAYAARGTNTGYAAYCARACNGGNGARYTNGARMGNATG AARATGGARATHCARCARYTNGAYACNACNGTNAARAAYYTNACNGAYTCNYTNGARGAR GARAARAARTCNAARGAYCARACNACNGCNTCNYTNTCNTCNTCNYTNACNGCNAARACN CARGARTGYTCNGAYTTYAARCARAARTGGGARGAYGARATHGAYGCNAAYAARACNYTN AARMGNMGNCAYGCNAGYAAYGTNAARGAYYTNACNMGNCARYTNCARCARGCNAARMGN MGNYTNGARGTNYTNGARGGN------AAYACNGARGCN------ATGGGNTCNMGNTCN AAYTCNAAYGGNAGYYTNAAYTCNGTNGCNGARGGNAAYAGYTCNGCNGGNGGNAGYCAR GCNGCNGCNTCNAGYCARGARTTYCCNGTNATHACNGARCARGTNGARATHGAYAARCAY GTNYTNATHGARMGNATHGTNMGNYTNCARAARTCNCAYGCNMGNAARAAYGARAARYTN GARTTYYTNGGNGARCAYATHCARCARYTNYTNGTNGARATHAARAARAARACNAARATH ATHCARAGYTAYGTNYTNMGNGARGARGCNGGNACNYTNTCNTCNGARGAYTCNGAYGCN AAYAARYTNYTNTCNMGNAARGGNGGNATHATGGCNTCNGTNTAYTCNYTNCAYCARCAR GCNATGACNYTNGAYYTNTCNYTNCARATHAAYAARAARYTNCARGCNGTNYTNGARGAY ACNYTNYTNAARAAYATHACNYTNAARGARAAYYTNGAYACNYTNGGNGCNGARATHTCN MGNYTNTCNCARGTNAAYMGNAARYTNCARYTNCAYYTNCARGAYYTNGARGARGCNCAR GGNGGNAARGAYGARACNTTYCARACNTTYGTNYTNCAYGAYGARGAYCAYACNYTNGGN AAYGCNYTNAARTAYATHYTNAAYAARAAYCCNGAYGTNACNTTYGTNGGNTAYAGYATH ACNCAYCCNTCNGARACNAARATHAAYYTNMGNATHCARACNGCNGGNAARCCNGCNGTN CARGTNYTNAARCARGGNYTNAARGAYYTNAARCARYTNTGYGGNCAYATGYTNACNACN TTYGARTCNTCNACNAARTAYTAYAARGARAAYCAYYTNGAY------GAYGAYATGGAR CARTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GCNGARACNGARGTNCAY AARCARYTNCCNAAYTAYACNAAYATHGTNGARTCNYTNGARGAYAAYTCNMGNGGNACN GTNAARCARAGYAAYATHAARACNYTNGCNAARGCNCARGARGAYYTNGCNGAYGCNATH TCNAAYCAYGGNACNYTNATHCAYCARYTNAARAARYTNAGYCCNAAYTCNACNACNACN ATGGGNAGYTAYAAYAARTTYAARAAYAAYTGYATGAARGAYTCNATHYTNYTNACNYTN GCNTGYGARGGNACNAGYGTNTTYGGNGGNTTYGCNATHTTYTCNATHYTNGGNCAYATG GCNCAYGTNTCNGGNAAYTCNATHGAYAGYTTYGCNMGNTCNGGNCCNAARTCNAARTCN ACNCARACNAAYAARCAYGAYMGNMGNTCNAARMGNCARTCNAAR------GTNGAYACN GCNGCNGAYAAYTGYTCNAGYAAYGAYYTNGCNYTNAAYACNGARCCNTCNYTNGARGAY GGNGCNATGTCNGCNATHCCNYTNGCNATGTGGGAYTTYGARCAYTGYGAYCCNAARAAR TGYAGYGGNAARAARYTNAGYMGNYTNGGNTAYGTNMGNACNYTNMGNYTNAAYCARMGN TTYGGNGGNYTNATHYTNTCNCCNGTNGGNACNAARTGYGTNGCNCCNGARGAYMGNCAR TTYATHGARGCNAGYGGNGTNGCNGTNATHGAYTGYAGYTGGGCNAARYTNCARGARACN CCNTTYGGNMGNATGAARGGNGAYAARYTNMGNYTNYTNCCNTAYYTNATHGCNGCNAAY CCNATHAAYTAYGGNAARCCNTGYAARYTNTCNTGYGTNGARGCNTAYGCNGCNGCNYTN TAYATHACNGGNTTYGTNGARGARGCNGARYTNYTNYTNGAYAARTTYAARTGGGGNCCN ACNTTYATHTCNATHAAYACNGARYTNYTNGAYAARTAYAGYAARTGYGTNACNAGYCAR GAYGTNGTNGARGARCARACNMGNGTNYTNGCNMGNTTYCARCARGAYAGYGCNGCNGAY AARATGAARGAYTGGATGGARATGGAYGCNGAYGTNGAYGTNTGYAAYCCNAAYMGNCCN YTNTAYCCNCCNTCNGAYACNAGYTCNGARGARGARAGYGCNGARGARGARGARGARGAY GARGARGARGARGARGARGARGARGGNGGNGAR--------------------------- ---AARATGGCNATGGARTGYGCNACN------CAYGAYATHGGNTTYATGATGCARATH GGNGARATHGCNCARAGYACNGAYGAYAARCARAARATGAAYTTYGTNTGYGAYCAYGTN CCNCARYTNGCNGAYYTNACNATGTGYATGATHAARAARGTNTCNTCNTGYGTNCCNGCN GCNGTNCAR---CCNGTNATGAARGCNYTNCCNGAYAARCARMGNATHATHGAYGCNYTN AAYTAYGTNTGYGARGAYAARACNGTNATHATGAAYCARTGYATGAGY---ACNAAYATG ATGCCNYTNATGCARTGYTAYCARCARCAR---------GTNGCNACNGTNGTNGCNGGN GCNGCNGGNAGYAGYGAYGTNACNCARYTNATGTGYAARGCNATHCAYGCNGARGARAAR TGYTTYAARATHCAYCARGGNACNTGYAGYGAYGARTAYGTNAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TAY GGNYTNTTYGCNYTNGARGARATHAARGTNACNCCNAGYGGNTTYCAYYTNACNCARGGN CCNGGNAAYTAYAARATHCCNTCNTTYGGNAAYATHCCNATHGARTTYAAYGTNTCNYTN GTNGARGAYAGYCAYAAYCCNAAYGCNGTNTTYGCNTCNAARGGNGTNGGNGARCCNCCN YTNYTNYTNGCN------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TCNGCNGCNTCNTCN MGNYTNTCNTGYACNGARGARTTYACNMGNCCNGGNGAYMGNGCNGAYTCNGTNCCNATG GTNACNMGNGGNTGGCAYCARGGNGGNGAYGGNGTNYTNCARACNCCNTCNCCNAGYGAY AGYGGNGTNGGNGARYTNGARGCNATHYTNMGNGARAARGAYGCNGARATHAAYACNYTN MGNGARGTNATGGAYMGNAAYGARMGNGCNATHYTNCARGTNTAYGARGARMGNAARAAY GCNTGGGCNYTNGAYACNCARGAYYTNMGNGARGAYTAYGARMGNAARYTNAARATHCAR AGYMGNAARTCNTAYAARACNGARCARGTNYTNTCNYTNCARGTNTAYAARYTNCARGAR GARAARAARAGYYTNACNGARGARAARGAYAARATHGTNAGYGARGGNGARTCNYTNAAR AARGARYTNGARGCNACNAAYGCNGARYTNTGYAARYTNMGNAARCARYTNGARYTN--- ---AARTCNGARCAYGAYGGN------YTNGAYTCNCCNGAYACNAAYGAYGARYTNGCN ATHAARAAYAARGARGTNATHAAYYTNCAYACNCARYTNCAYACNATGCARGTNGAYATG GAYAARAARGGNAARGARYTNTCNGARAARACNAARGAYYTNYTNAGYTGYAARGAYGAR GTNGAYAARYTNMGNAARGARATHGARAARATHAARAAYCCNGCNGTNATGTGYGARGCN TCNAGYCARACNCAYTCNGARAGYGARATHTCNAGYTCNGARAAYYTNAARCCNTCNATG ATGGGNGARMGNGARMGNACNATHCARACNYTNCARGARGARYTNGAYAARYTNAARAGY GAYGTNYTNGARATGGAYGAYMGNCAYGARCAYGARAARGARCARTGGYTNGARGARAAR AAYAARGTNATHMGNTAYCARAARCARYTNCARYTNAAYTAYGTNCARATGCARMGNAAR AAYTCNACNYTNGARACNGARGTNCARCARYTNACNYTNGARYTNGARAAYMGNGAYATG AARYTNATHGCNYTNAGYGGNGARGARAGYGTNTGYTCNTTYTTYYTNTCNGTNYTNTTY ATHGCNGCNGTNYTNAAYGTNGTNTCNYTNATHTAYATGCAYCARTGGCARCCNACNACN GARTCNYTNATGCCNTAYTTYATHATHATGGGNACNTGGGGNATHACNGAYGGNTTYTGG ACNGCNCARGTNAAYAGYYTNATGGGNGTNATHTTYCCNGARAARTTYGARGARGCNTAY GCNGGNYTNMGNATHACNCARGGNYTNAGYGTNGCNGTNGCNTTYGGNTAYTCNAGYATG YTNTGYATGACNGCNAARATHTAYATHACNGTNGCNGTNTGYGTNGTNGGNYTNATHGGN TAYYTNATHATGGARGGNATGYTNMGNTTYGGNAGYAARAAYAARGCNATHCCNYTNAAR CARACNTCNGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TCNGCNACNTTYYTNCAYGGNACNATGGGNGTNGGNCARYTN AARGTNTCNTAYCCNCARYTNGAYTTYACNCCNAGYGCNYTNTTYGCNATGGGNTCNCCN ATHGCNTTYTTYYTNTCNYTNMGNGGNATHGAYGARATHGGNGARTTYTTYCARYTNCCN ACNTGYCCNMGNGTNTTYAAYATHTTYCAYCCNTTYGAYCCNATGGCNTTYMGNATHGAR CCNYTNATHMGNCCNACNATGTCNCARGTNAARCCNGTNCARGTNCCNCAYTAYAARGGN MGNAARMGNYTNCAYYTNGARTTYAARGAYGCNGTNACNMGNTAYGGNTCNGAYATHAAR CAYMGNATHATGGAYTCNYTNAARAGYACNTGGAAYAGYATHAAYGAYTTYGCNAARGCN CAYAARTCNGARGGNAARCARATGGARACNGARGTNCARTCNGARGTNGAYYTNATGATG AARCARATHTCNCARCARCAYGTNGAYGAYGAYGTNGCNTCNGTNTCNTCNATGGCNGAR GARGARATHCARATHGGNCARYTNAAYGARGGNCARMGNGTNGAYCAYCARYTNCARGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ACNTCNAARGCNGGNTAYGCNAARATHAARCARGAR TTYYTNYTNYTNAAYTAYAARCCNACNATHCARACNGARTAYYTNAGYGARGAYACNAAR MGNAARYTNGAR------GARTCNAARGAYGARCCNGARCARAARGARGAYGAR------ ---------------------GARTCNCARCCNGCNAGYAARAARACNAARYTNAARGGN MGNAAYAARCARMGNCCNMGNCAYCARAARATHGAYGTNAARGAYAARYTNTGYCCNGCN ATHAARGAYGGNMGNGARTGYAARTTYGGNGARAAYTGYAARTTYAAYCAYGAYYTNAAR GTNTAYATGGARAARAARYTNCCNGAYATHGAYATGAARTGYGCNGTNTAYGARAAYYTN GGNTTYTGYMGNCAYGGNGTNACNTGYMGNTTYTCNAGYAGYCAYATHGGNGARAAYATG GARAAYYTNGTNAAYCAYGARATHTAYGAYAARGTNAARACNCCN---AGYTTYYTNAAY ACNYTNAGYGAYGARAAYMGNACNAARYTNTGGAARMGNAARTAYGAYTTYTCNAARGCN YTNAARTCNGTNMGNGARGTNCARAAYGARTTY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TAYAGYCCNYTNCCNAARGAYAARGARGTN GAYGTNGAYAARYTNACNAARCCN------------------------GARTGY------ ---------------YTNGAYGAYGTNGAYATHMGNCCN---ACNCCNMGNGARGTNAAR AARATHGAYTTYCARAAYCARYTNTTYYTNGCNCCNYTNACNACNGTNGGNAAYYTNCCN TTYMGNMGNGTNTGYAARAAYTAYGGNGCNGAYATHACNTGYAGYGARATGGCNGTNGCN TCNCARYTNYTNAARGGNAARGCNGCNGARTGGTCNYTNATHAARMGNCAYCCNAGYGAR GAYGTNTTYGGNGTNCARYTNTGYGGNTCNTAYCCNGAYATGATGTCNAARTGYGCNCAR YTNYTNGTNGARACNTCNAAYATHGAYTTYATHGAYATHAAYTGYGGNTGYCCNATHGAY YTNATHTTYAARAARGGNAGYGGNAGYGCNYTNATGGGNAARGCNACNAARYTNGARCAR ATGTGYMGNAGYATGATGGGNGTNATGGGNGARAARCCNYTNACNGTNAARGTNMGNACN GGNATHTTYGAYCAYAARAAYAGYGCNCAYAAYYTNATHCCNMGNYTNAARGAYGCNGGN GTNTCNYTNTTYACNATHCAYGGNMGNTCNMGNGARCARMGNTAYACNAARYTNGCNGAY TGGGAYTAYATHGAYAGYTGYGCNGAYYTNGGNMGNCCNATGCCNGTNTTYGGNAAYGGN GAYGTNYTNTCNTAYGARGAYGCNAAYYTNCAYATGAGYMGNAAYAARGTNTCNGGNGTN ATGATHGCNMGNGGNGCNYTNATHAARCCNTGGATHTTYACNGARATHAARGARCARMGN CAYTGGGAYATHTCNTCNTCNGARMGNTTYGAYATHYTNAARTCNTAYACNAAYTAYGGN YTNGARCAYTGGGGNTCNGAYTTYCARGGNGTNGARGCNACNMGNMGNTTYYTNYTNGAR TGGYTNTCNTTYYTNCAYMGNTAYATHCCNGTNGGNGTNYTNGARCARGTNCCNCARAAR ATHAAYGARMGNCCNCCNTAYTAYATHGGNMGNAAYGAYYTNGARACNATGATGGCNAGY GCNAAYTGYGCNGAYTGGATHAARYTNAGYGARATGYTNYTNGGNCCNGTNCCNGAYAGY TTYCARTTYYTNCCNAARCAYAARGCNAAYGCNTAYCAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNTTYGAYGARTGYTCN TCNCARAARACNGTNTTYGAYCARACNGCNYTNCCNYTNGTNGARGAYYTNATGYTNGGN AARAAYGGNYTNYTNTTYACNTAYGGNATHACNGGNTCNGGNAARACNTAYACNATGACN GGNTTYCCNCARGAYCARGGNGTNYTNCCNMGNTGYYTNGAYGTNYTNTTYAAYAGYATH GGNGARMGNCARGCNAARAARTAYGTNTTYMGNCCNGAYCAYATGAAYGGNTTYGARGTN CARAGYGARGCNGAYGCNATGATGGARMGNCARAARAARGAYATHYTNCCNGGNYTNACN TCNGCNAGYAARACNTCNYTNAARMGNGCNGAYGCNGGNGAYACNGAYMGNYTNGTNGAY CCNACNGTNGTNGARGGNGTNGARGAYGARAAYAAYTAYTCNGTNTTYGTNTCNTAYATH GARATHTAYAAYAAYCAYGTNTAYGAYYTNYTNGARGAYYTNCCNTAYAAYACNATHACN GGNTAYAARCCNCCNCARTCNAARATHYTNMGNTCNGAYCCNTCNGAYAAYATGTAYGTN CAYAAYTGYACNGARGTNGARATHAARCARCCNCARGAYGCNATHGAYGTNTTYTAYAAR GGNCARMGNMGNMGNAARGTNGCNCAYACNGCNYTNAAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GTNATHGARAARGARYTNGAYYTNYTNCARGARAARYTNCARGARAAR GAYATGATHGTNTCNGAYYTNCARMGNTCNAAYTCNTCNYTNYTNGARYTNATGGAR--- AARTCN---TCNGGNAGYGAYMGNAGYGAYMGNYTNACNGTNCAYAARYTNGARGCNGAR YTNMGNAGYATHMGNGCNGARMGNGARCARATHGTNGCNGTNGTNAGYGARAARTCNMGN GARAAYTCNTCNYTNAARTCNGARATHCAYMGNYTNATGGARYTNGTNTCNTCNGGNCAR TCNGCNYTNGCNAARTCNCARCARGAYAAYGTNAAYYTNGAYCARATGAAYCAYACN--- AAYMGNAGYAAYGAY---GARGAYGAYGARATGAARMGNGARGCNYTNAAYAAYATGGCN MGNYTNATHMGNGAYAARGAYACNGARATHGARGCNYTNACNCARAARAAYCARACNYTN GTNGCNGTNYTNCARGARTCNTCNTCNCARTCNGCNGCNGCN------YTNGGNCCNYTN YTNAARGARAARGARACNYTNAGYCARCARGTNAAYACNYTNGTNTCNGARMGNGARCAR YTNATHGCNTGYATHACNCARAARCAYTCNGARTCNYTNGCNTTYCAYGCNGARGTNCAR MGNYTNACNACNGTNYTNACNGAYACNCARCARGCNGCNGAYAARYTNAARGCNGARTAY TCNGCNYTNATHCCNTCNTTYGARGGNAARGCNAARGCNYTNYTNAGYGTNCARCARGAR YTNGTNGARTGYCARCARAARYTNAARGARYTNGARATHAGYCAYGGNGARYTNATHCAR MGNACNACNAAYCARCARCARCAYGCNTCNAAYTCN------------CARGCNATGGAY GARYTNGARGCNGARATHGARAARTAYAARGCNYTNGARAGYGAYCAYAARTCNACNATH ATGGARCARAGYAAYCARATHCARGGNYTNACNCARAARYTNAAYGGNATGGARGAYAGY YTNGCNTCNAARCARGCNGARTGYACNCARYTNAARAARCARYTNGAYAAYAGYAARTTY CARYTNACNGGNYTNATGGCNGARATHGCNGARGCNAARTCNGARMGNGARYTNGTNAAR CARAARAAYGARTCNCARGGNGARGCNTCNCARCAYYTNMGNAAYGGNYTNAAYCARATG ACNYTNGCNATHAARGAYAARGAYGTNGARATHAGYTCNYTNAARGARCARYTNGCNACN YTNAAYTCNGTNYTNCARAAYCARAARGGNGARCARGAYCARGTNTCNCARYTNATHMGN GAYCAYGARTCNGCNYTNGCNTAYAGYMGNCARYTNCARCARGARAARGAYTCNAGYYTN ATGATHGCNGARCARMGNYTNCARGAYTGYCARGCNYTNAARACNGARYTNTCNGCNCAY AARGAYAARGTNTTYAARYTNGARMGNGARYTNGARMGNYTNMGNAGYCAYYTNATHGAR ATHGARGARGGNTAYACNAAYGARGCNYTNGGNGCNGARGARMGNGARAARGARYTNMGN AAYMGNYTNGCNGTNGCNGARGARCARYTNGCNTCNTCNTCNTCNCAYGTNAARYTNGCN AGYCARGARGCNCARMGNCARATHGARAGYYTNCARTCNCARYTNCAYCAYATHGCNAGY CARMGNGAYGCNGCNTAYATGCARGTNGCNACNACNCARGARCARTGYCARCARTAYGCN TCNTCNYTNTAYAAYYTNCARYTNGTNYTNGARCAYTTYCARAARGARAARAAYTCNGCN ATHGCNYTNGARACNGARAARTAYCARGARCARGCNAARTCNYTNGAYGGNAARGTNAAR GAYYTNGARAAYGARYTNAAYGCNACNMGNACNGAYYTNTCNGARGCNYTNGAYGGNYTN GARGCNGCNTCNMGNYTNAGYGARCARATHGAYMGNAARGARGAYGCNYTNAARGCNYTN AARGARGARGTNCARYTNMGNGARCARTCNYTNAARGCNGCNGARGARGARATHMGNCAR YTNAAYGCNAARAARGARGCNAARGTNGAYAARGARYTNATGCAYAAYATGGTNATGACN TGGYTNACNTCNCCNGAYAARAARMGNCARGARATHGTNCARYTNATHGGNCAYGTNYTN GGNTTYAGYGCNGAYGAYTTYTCNAARATHGARTCNGCNCAYAGYCARAAYAGYYTNTGG ATHGGNTTYTTYAAYMGNAGYAARGARGARCCNACNACNCCNACNAARACN------AGY CARTCNTTYTCNCARYTNTTYGTNAARTTYYTNGARAARGARTCNTCNCCNGCNCCNGCN CCNGTNCARYTNCCNGCNGARGCNATGGCNGCNGARGCNCARAAYMGNCAYAARCARACN TTYAAYCCNTTYATGGCNCCNMGNCAYGTNTCNCAYTCNACNGAYGGNTCNAARTCNTCN GGNTCNTCNTCNTCNCAYYTNYTNYTNCCNCARGAYAAYYTNCAYCCNTCNCCNYTNTTY GCNCCNGTNACNAGYGGNCAYGGNCCNGCNGARAGYGCNATHYTNAARGAYGTNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGNTAYATGGCNCCNGARYTNYTNGAYAARACNYTN AAYCCNGCNCAYTTYGARTCNTTYMGNTGYGCNGAYGTNTAYGCNTTYGGNYTNGTNATG TGGGARATHGCNMGNMGNGCNMGNCCNTAYTGYGARGARTAYMGNGTNCCNTTYTGGGAY YTNGTNCCNGGNGAYCCNAGYYTNGARGAYATGAARATGGTNGCNGTNGAYCARCARCAR MGNCCNGTNATHCCNAAYAAYTGGTCNCARGAYGTNACNATGCARGARATGGARAARYTN ATHMGNGGNTGYTGGTCNCARCAYCCNTCNAGYMGNYTNAARATHYTNMGNGTNAARAAR AAYYTNCARMGNYTNYTNGCNGCNACN------GARCAYAAYCARGAYAARCARAAYYTN TCNGGNAARATHYTNGAYGGNAGYACNACNGCNAAYAGY---------AAYAGYGTNATH ATGYTNTTYGAYYTNAAYGAYTGGCARYTNGGNAGYGAYYTNYTNTGYGARGAYYTNAAY ---------YTNTTYMGNGAYCAYTTYGAYTGYYTNAGYCARTTYTCNAAYCAYATHTCN AGYTGYATHYTNAAYAGYACNATHTTYTTYMGNGARAGYYTNATHGAYGCNGGNATGGCN ACNCARCARACNYTNCAYGAYATHACNTGYAAYTTYGCNGARGAYATHGTNTAYTGYYTN GAYGCNCCNYTNAGYACNCAYTGYCCNYTNATHGTNGTNGAYACNATGGTNACNGCNYTN TAYMGNTTYYTNCCNCCNGCNTGYGCNACNYTNCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TAYTAYGARYTNAARAGYAARGTNGTNGTNGGN AGYCCNGTNACNGARATHAARAAYGCNACNATGCCNATGMGNGCNAAYYTNAARCARCAR YTNCARMGNCARCARYTNTAYGAYCARGARAARMGNCARAARTCNATHAARAAYGGNYTN ---GGNACNMGNACNATGGGNATHAAYGTNCCNCAYCAYATHGARTCNACNTCNGTNCCN TCNAAYGTNYTNCARGTNMGNACNCARYTNCARCAYCCNACNAARTAYCAYGTNMGNCAR AARCARAAYMGNCARGTNCARGAYTTYYTNCARGARCAYCAYGGNACNCAYATGCCNATH CARTCNYTNCCNGTNAAYYTNGCNACNYTNACNAGYCCNGAYCARCARCAYCAYTAYYTN CARGCNTCNAGYAGYGCNCCNGAYCCNGAYATHTCNAGYCCNYTNATHGAY--------- GGNGGNAAYGAYTTYATHCCNACNAGYTTYGAYYTNYTNGGNGAYYTN---ACNGTNGAR CARYTNGARYTNGGNAGYATHYTNAAYGAYAGYGAYYTNATHGARATHCARCCNTCNYTN GGNACNGARGGNYTNAAYCARAAYGGNATGGTNTCNAGYTAYGAYACNYTNGAYGCNGAR GGNATHCCNCARGCNACNGTNGGNGTNAAYTCNTGYCCNACNTCNAARTAYYTNAGYCAR GAYYTNACNAAYACNGGNATHATGTCNATGCARGAYGARATGTGGMGNAARGARMGNATH AARAARGAYAAYCAYAAYATGATHGARMGNMGNMGNMGNTTYAAYATHAAYGAYMGNATH AARGARYTNGGNGGNYTNYTNCCNAARTCNATHGAYCCNGAYAGYMGNCARAAYAARGGN ACNATHYTNAARGCNTCNGTNGAYTAYATHAARGCNATGCARGAYGARCARMGNAARATH AARGGNATGYTNGAYGARAARMGNAARGCNGARYTNGAYYTNMGNAARGTNYTNATHMGN YTNAAYCARATGAAYYTNGTNYTNAARTCNCAYGGNATHGAYTCNGGNGGNYTNGGNGAY YTNGAYYTNGCNTCNAGYGTNGCNTCNAAYCCNTCNAAYTTYYTNACNTCNCCNGCNCCN TCNAGYCARGTNAAYTCNATHCAYCAYAAYACNATHACNAAYAAYAAYTCNAGYACNGTN ATGTCNCCNATGCAYGAYYTNATGGAYGAY------TCNCCNGTNAGYGGNGAYCCNATG YTNATGTCNGCNCCNGTNAGYCCNGARCCNGAYGARGTNGGNTTYCAYTTY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AAYGCN TAYGGNCCNAAYTCNCARCAYTTYYTNAARGAYTCNGTNACNAGYCCNTGGGARMGNGCN GTNGCNGCNAAYAARGTNCCNTAYTAYATHAAYCAYGAYACNGARACNACNCARTGGGAY CAYCCNCARYTNACNGCNYTNATGGAYGCNYTNATHGAYYTNAAYAARATHMGNTTYGCN GCNTAYMGNACNGGNATGAARYTNMGNATGYTNCARAARAARYTNTGYYTNGAYACNGTN TCNYTNCARATGGCNATGGARTCNTTYGAYAGYCAYGGNYTNMGNGGNMGNAAYGAYAAR YTNATGGAYGTNGGNGARATGATHGARTGYYTNTCNAAYATGYTNGARTCNGCNGCNAGY CARCAYCCNCARYTNGTNAGYGTNCCNYTNAGYGTNGAYYTNACNYTNAAYTGGATHYTN GAYGTNTAYGAYAGYGTNMGNAGYGGNAARATHMGNGTNYTNTCNTTYAARGTNGCNATH GTNATGYTNTGYAARGCNCARYTNGARGAYAARTAYMGNTAYYTNTTYMGNYTNATHGCN GAYACNAAYGCNTTYGCNGAYCARMGNAARYTNGGNYTNYTNYTNCAYGAYTGYATGCAR ATHCCNMGNCARYTNGGNGARATHGCNTCNTTYGGNGGNAGYAAYATHGARCCNAGYGTN MGNAGYTGYTTYGARAARGCNAAYGGNMGNCCNGARATHGARGCNTAYCAYTTYYTNGAY TGGYTNAARYTNGARCCNCARTCNATGGTNTGGYTNCCNGTNYTNCAYMGNYTNGCNGCN TCNGARACNGCNAARCAYCARGCNAARTGYAAYATHTGYAARGARTTYCCNATHGTNGGN TTYMGNTAYMGNTGYYTNAARTGYTTYAAYTTYGAYGTNTGYCARAAYTGYTTYTTYTCN GGNMGNACNGCNAARAGYCAYAARYTNACNCAYCCNATGCARGARTAYTGYACNACNACN ACNTCNGGNGARGAYGTNMGNGAYTTYTCNAARGTNTTYAARAAYAARTTYAARTCNAAR MGNCAYTTYAARAARCAYCCNMGNMGNGGNTAYYTNCCNGTNGAYTCNCAYYTNGARGGN GAYAGYYTNGARAGYCCNAAYCCNTCNCCNCARCAYAGYATHTCNCARGAYATGCAYTCN MGNYTNGARATGYTNACNAGYMGNATHGCNGARGTNGARCARMGNCARGGNGGNGCNGCN GAYYTN------------------------------------------GARGAYGARCAY CAYYTNATHGCNCARTAYTGYTCNAGYYTNAAYGGNGARCCNAAYTCNCAYGCNYTNAAR AGYCCNATGCARATHATGATGGCNGTNGAYGTNGAYCARMGNCAYGARYTNGARGCNATG ATHCARGAYYTNGARGAYGARAAYAARACNYTNCARYTNGARTAYGAYMGNYTNCARATG GCNGCNTCNGARMGNGTNTCNGAYCARTTYMGNYTNTCNGGNAGYGAYAAYGGNAAYAGY TCN---------------MGNGAYGAYGARATGYTNGARGARGCNAARYTNYTNMGNCAY CAYAARGGNMGNYTNGARGCNMGNATGMGNGTNYTNGARGAYCAYAAYTCNCARYTNGAR GCNCARYTNTCNMGNYTNMGNCAYYTNYTNCARCARGCNCCNGGNGAYAARAGYTTYATH TCNYTNGAYTCNTCN---MGNGCNACNCCNYTNAGYACNCCNTCNTCNTCNCARAGYTCN TTYCAYATHGGNACNCCNAAYTAYMGNYTNGCNCCNCARATHGARTCNACNCCNCARTCN AAYGGNCAYATG------AGYYTNACNGAYGAYCCNGAYYTNAGYGGNATHATHGGNAAR GTNAAYAGYCCNCCNCAYTAYAAYGTNAARAGYAARCCNGGN---AAYGTNGGNGAYYTN TTYCAYATHGCNGGNGARYTNGGNGARGCNGTNGGNTCNYTNGTNACNGTNATGACNGAY GARGAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGGCNGCN CCNACNAAYACNGGNTCNTGYYTNCCNTGYGAYGAYTTYATGAARTTYCARGAYGCNYTN AARMGNYTNMGNATHATHGAYGAYMGNATHGTNCAYGCNYTNAAYAARACNATHCCNACN CARTCNTTYMGNGGNCARGTNGAYGTNACNGCNAAYTGYAARCARATHTAYGARGAYATH GARAARGCNTAYAGYCARMGNGARAARTCNATHCARCAYTGYATHMGNYTNGTNGGNGAY GAYGTNAARAARATHAAYGARAARMGNCARCARGAYCCNGAYAAYYTNGCNGTNYTNAAR ACNYTNMGNMGNGARCARACNAARYTNMGNYTNATGCARCARGARATGAAYATHGARGAR GTNGTNAARGAYMGNACNYTNAARGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNYTNMGNGARAARGAYATHGTNTTYATHAARGARYTNATH TAYGGNCCNYTNGGNGGNGARACNGGNGGNTGGCCNTAYAARGGNMGNGAYGARAGYAAR TCNTTYYTNTAYGARATHATHTCNAAYAARCCNACNGGNATHGAYGTNGAYAARTGGGAY TAYTTYGCNMGNGAYTGYTAYCAYYTNGGNCARYTNAAYAAYTTYGAYCAYAAYMGNTTY ATHAARTTYGTNMGNGTNYTNAAYGTNGAYGGNMGNYTNMGNATHTGYGCNMGNGAYAAR GARCARGCNAAYYTNTAYCARATGTTYCAYACNMGNTAYAAYYTNCAYMGNTCNGCNTAY CARCAYAARGTNAAYTGYGCNATHGARATHATGGCNGTNGAYGCNYTNGTNAARGCNAAY GAYTTYATHAARTTYCARGGNMGNAAYGGNCCNYTNAARYTNTCNAARACNGTNACNGAY CCNATHGCNTAYGARCARGTNACNGAYAAYGTNYTNTGGCARATHTAYATHTCNCARGAY YTNGARYTNCARCCNGCNMGNGAYATHATHAARMGNYTNTTYAARMGNAARYTNTAYYTN TGYYTNGARGARAAYGAYAARGARYTNACNAARGGNMGNAAR------ATGAAYAAYYTN MGNGAYMGNATHATHAAY---TAYTCNGARCARATHTCNAARCCNATHCARTCNACNGAY TTYMGNYTNCARATHGTNGARATGGAYTTYGGNAARAARGAYAARGAYCCNYTNAARGAR ATGTGGTTYTAYTCNAARAARGAYATHAAYMGNCCNATHAARGTNCARAARACNGGNYTN TTYGTNCCNCCNAARTTYAAYGAYAAYTGGATHMGNATHTAYAGYMGNGTNGAYGAYGAR GCNACNTGYGARGCNATHMGNGARAGYTTYGARAAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARAARCAYAARGAYCAYGARAARGTNCAYCAYCCNGGNAGYAAR GAYCARTTYGARGARGTNTGGGARAARGAYGAYGAYYTNAARGAYCARGARTTYGAYCCN MGNACNTTYTTYTTYACNCAYGAYATHAAYGGNGAYATGTTYTGGGAYGCNGARGARGTN GARGCNGTNYTNCARMGNGARYTNGAYAARGTNTAYGAYTCNAARGAY---CCNGARGAR GAYGAYCCNATGGARMGNGARGARGARATGMGNMGNATGMGNCARCAYATHTTYAARGAR ATGGAYMGNGAYAARAAYGCNATHATHTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGGTNGCNTTYGGNYTNCAYYTNGGNGCNTGY TCNGCNTGYATHGCNGTNCAYAARGAYGGNAARACNGARGTNATHGCNAAYGAYYTNGGN GAYMGNGTNACNCCNGCNGTNGTNGCNTTYACNGAYCAYGARATHTCNGTNGGNGCNGGN GCNAARCARGCNGCNGTNMGNAAYGCNGCNAAYACNGTNATGCAYGTNAARGAYYTNATH GGNAGYGARGGNGARGAYGAYCARGCNAARGARTAYATGCARAARCAYCCNGTNGGNGTN AGYTTYCARAAYAARACNATGGTNTTYAAYGTNGARTAYCARGGNAARAARGCNCARTAY ACNCCNAGYAARATHYTNGARYTNATHTAYGGNAARYTNYTNGARACNGCNCARAGYCAR AGYGGNGGNGGNATHAARGAYGCNGTNATHGCNGTNCCNTCNGAYTTYACNTCNACNCAR MGNGARTAYYTNAGYGAYGCNGCNACNAARGCNGGNTTYAARGTNYTNMGNATHATHAAY GARCCNTCNTCNGCNYTNYTNGCNTTYGAYGTNGGNCARTTYGAYGARACNGARCAR--- TTYAARGTNYTNGTNTAYMGNTTYGGNGGNACNTCNCAYGAYGCNACNATHGTNAGYGTN GARCAYGGNATGTAYTGYATHGARGCNMGNTGYACNGARAAYCARTTYGGNGCNGAYAAR YTNACNGARGTNYTNYTNGAYTTYYTNGCNAARGARTTYAAYMGNCARTTYMGNTGYGAY GTNMGNGARAGYAARMGNTCNATHAGYAARYTNATGYTNGCNGCNGARMGNTGYAARCAY GCNTTYTCNACNYTNCCNAAYGCNCARTGYAGYGTNGAYTCNYTNTAYGAYGGNATGGAY TTYTCNTAYAAYATGTCNMGNGCNMGNTTYGAYATGYTNGCNACNCCNYTNYTNTCNCAR TGYACNCARYTNGTNCARCARGTNYTNGAYACNGCNAAYTGYACNAARGARGAYATHTTY AARGTNATHYTNTGYGGNGGNGGNGCNAARTCNCCNATHGTNAARAARATHATGGCNGAY TTYYTNCCNTCNGCNTCNYTNYTNAAYTCNATHCCNGARGAYGARGTNATHGCNATHGGN GCNGCNAARGARGCNGCNYTNYTNGARGGNTGYGARGAYGAYAARCARAARATHTCNGAR GARAARAGYTTYACNTTYAARTCNYTNTCNAARGCNATHGCNGTNMGNGTNAAYTCNCCN GARATHCARGTNGTNYTNCCNCARMGNTGYYTNATHCCNGCNMGNMGNCARCAYACNYTN ACNYTNCCNTCNTCNCARACNAGYGTNAARYTNGARATHYTNCARGTNGAYGARTCNATH ACNTCNGARTCNCARGARCARYTNYTNGCNAARATHATHYTNMGNGAYYTNCCNGCNGGN TCNAGYATHAARTCNAGYTTYCAYYTNACNMGNCCNACNCCNCCNAGYTTYCCNGAYTCN TTYAGYGTNTCNTTYCARGAR------------------ATHATHAARTTYCARGGNCAY GTNGTNAGYGCNAAYAAYGGNACNTGGTAYTAYGAYTTYCCNAAYAARMGNGCNMGNTAY GAYCAYAAYAARGGNCARACNAAYAAYTTYTGYGAYGGNCARAAYYTNAGYCCNAARGAY CCNAARGCNGAYTGYCARYTNTAYTTYACNCCNACNGARGAYTTYATHGTNTAYTAYCCN GGNACNACNYTNTGYTGYMGNYTNTGYGGNGCNAARGARGGNTGYACNATHYTNMGNCCN GAYTGGYTNAARCARGGNTCNTAYATGGTNCCNTCNGARACNATHAAYGGNGTNAAYTGY TAYGGNTGGGCNAARAARGGNGTNGTNGCNAAYGCNGAYACNTGGTAYGARTCN---AAY GGNGTNCCNTGYMGNTAYCAYGARATHYTNTAYGGNATHYTNCAYAAYYTNACNTTYATH CCNAGYACNTTYAARGTNGGNCARYTNGAYCCNATHGTNTTYGAYGTNCCNGCNTAYTGY YTNAAYAARTGYCCNCAYCCNTAYGARGARGAYGAYGARGARATHATHGGNMGNACNGAR GAYGARTCNGAYGARGCNACNGAYTCNGAYGAYGAYGAYGAYGCNGAYGARGGNGTNAAR MGNGGNGARCCNAAYAARTTYGAYGGNYTNTGYGAYGGNGTNATGGGNGCNATGGCNYTN GTNCAYGCNGCNYTNCARGAYYTNYTNGARYTNAARGAYGARYTNYTNMGNCAYTCNYTN CCNCCNACNYTNYTNGTNCARYTNGCNATGACNAGYGGNAARGTNTTYMGNAGYATHAGY GAYYTNGGNAAYCCNGTNAGYGARYTNGTNMGNYTNGTNMGNGTNTAYTCNACNCCNTGG GARGARAARAGYGCNGCNYTNAARAARYTNCAYGARGAYTAYGARAGYAARCARMGNCAR YTNAAYATHGCNGTNMGNMGNYTNCARYTNGTNGAYGCNCAYTCNAARMGNGTNGCNAAR GARAARMGNATHATGAAYTGGGARAARYTNTTYTCNAARATGACNACNGCNAARGGNCAY GGNMGNMGNTGGAARTTYYTNATHGARACN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CARYTNGCNACNATGAARACNGARACNTCNTTYGARATG MGNAGYCARGTNTCNCARCCNCCNTTYTCN------------GTNGTNGGNCARMGNGGN GCNGCNAGYCARTAYTCNMGNTCNTAYACNGARCCNTAYTCNMGNAARGGNGCN---MGN ---AGYGARGAYGGN---TCNAGYGTNTAYGAYCAYGAYACNAARTTYTCNCARMGNAAY YTNATGAAYGAYGARMGNGAYMGNMGNMGNGAY---MGNGAYMGNATHGCNTCNCARAAY GAYGAYTAYGAYGAYGAYGAYGAYCCNAAYAAYTTYAARGARAARGTNATHACNCCNMGN TGGAARCCNAGYAAYTCNMGNGAYMGNMGNCCNCCNTCNTTYGARGARGCNACNMGNGAY AGYTCNMGNGARMGNTCNTCNGARGARGARTCNGAYGARACNGARACNGARGAYGAR--- ------------------TCNAGYGAYAAYGAYTCNACNMGN---AARMGNYTNACNACN TCNAGYGAYGAYAAYAGYGARTCNTCNGARTCNTCNAAYTCNGAYAAYACNAGYAAYMGN TCNTCNGTNAGYGGNGCNMGNGCNMGNMGNAGYAARAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARAAYTCNCCNCCNATHAARATHTCNAARACNGARAAYGTNACNCARCCNGARTAY CCNMGNYTNGTNGGNGARYTNGTNCARGCNYTNCCNCAYGTNCCNYTNGCNGCNTTYYTN GARTGGTTYATHGARACNTCNAAYCCNGGNCARTCNACNGGNTCNGAYGAYTCNGCNTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNTCNMGNATGCARATHTTYAAYMGN AAYGGNCAYTTYYTNMGNMGNATHGCNATHMGNTTYATHGAYATHGTNGCNGGNYTNGAY ATHACNCARGARGGNCAYATHGTNGCNGTNGAYAGYGTNTCNCCNACNGTNTTYMGNYTN ACNGARGCNGGNGAYYTNATHAARTGGTTYGAYTGYAGYGAYTAYATGMGNGARGCNMGN CARTGYCAYTGGATHAARGTNGCNGGNCAYATHGGNMGNTTYTTYATGACNTCNATHGAY CAYAGYGTNTGGTTYCAYCAYCCNYTN---------------AARYTNATGTCNACNAAR GARAAYMGNTTYAARAARACNGCNGARGCNYTNCARAARTCNGGNYTNTGGGAYATHGCN ATGAARACNGGNCAYYTNATHAARCARAAYCARGARYTNCARAAYGAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATGCCNCCNCCNGAYMGNTGGGARAAYTAYTCNAAR ATGGGNAARGTNATHYTNGGNACNAAYATHATGCCNATHAARGTNCCNYTNAARGARTAY TTYACNAGYTCNYTNCCNGARGARCARAARTTYTCNCCNTCNTCNYTNYTNGARTCNATG TCNGARCARAAYYTNAARYTNGGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TCNYTNTCNGGN AARGTNGTNCCNMGNATHATHYTNAARGTNGGNCARAAYCAYAARYTNCARTGYCARGCN GAYTCNGAYCCNTCNYTNACNCARTGGAARAARAAYGGNMGNGCNYTNAAYCCNGGNTGG GAYCARTTYAARGTNTCNMGNGAYGGNCAYYTNAARATHAARAAYGTNCARYTNTCNGAY GCNGGNYTNTAYACNTGYGTNGCNACNAAYGGNTTYGGNAGYATGAAYATHAAYTAYACN GTNGTNGTNMGNGAYGAYAARAAYAAYAARTTYCARGARGCNGAYAARYTNATHGAYCAR TCNCCNGAYCARGAYATGTAYAARCARAGYTCNTCNCCNGTNTTYGARGARYTNGARAAR ATGCARAARACNGCNACNGTNMGNAARCCNAARGGNTCNACNATHAARYTNACNTGYAAR GCNACNGGNAAYCCNYTNCCNCARATHMGNTGGTTYAARGAYGAYGTNGTNCARAARGAY CARGAYACNTAYAARAARYTNGARGGNGTNACNGGN------GARGAYAGYGCNYTNTAY ACNTGYGTNGCNAGYAAYMGNYTNGGNAARACNAAYTTYACNTAYAAYGTNCARATHATH GARAARATHAARGARCCNAARATHYTNTCNYTNCARCCNGCNAAYCARACNGTNTTYATH GGNGARACNGCNTCNTTYCARTGYAARATHAARTGYGTNGTNGARCCNGARGTNCARTGG YTNAARACNGTNGAYCARMGNATHCAR---CCNAAYCCNAAYGTNAARGTNATHYTNTAY AARGGNCARATGYTNATGGTNYTN---AAYGARGGNGTNATGCARGCNMGNCCNGAYGGN ACNTAYATHAAYAARYTNGTNATHAARGCNGTNMGNCCNCARGAYGCNGGNATGTAYGTN TGYTAYGTNATGAAYMGNCARGGNGAYGCNACNGGNCAYGCNTTYYTNCARGTNCARMGN GGNATGACNGARGGNCCNGGNACNTCNCARGAYATGTCNCARCAYGARTCNGAYAAYGAY TCNGARTCNACNGARGAYAAYYTNCCNYTNYTNATHGGNYTNCCNACNTGYGCNYTNYTN ATHATHATHYTNATHATHGTNTTYYTNYTNCARMGNAGYAAYGGNTGYAARAARACNAAY ACNGAYATHAARGTNCCNMGNACNCCNGTNCCNCCNGCNGARMGNGARGCNTAYTAYTAY AGYAAYTGYCARCARCAYCAYYTNCARCARTCNGTNAAYCCNYTNYTNYTNTCNMGNGAY AARYTNCCNAARACNCCNACNCCNTCNGTNGAYATGGCNCCNTCNGARTTYTCNTCNGTN TCNMGNAGYCAYCAYCCNCAYCAYTAYCAYAGYAAYCAYAAYTAYGGNTAY---GGNMGN GCNAGYCCNGTNTCNGARACNAGYMGNAGYTCNTGYGGNAGYCCNACNCCNAGYGAYACN AGYTCNCARAAYGGNGCNATHAGYCARCARATGYTNAAYGCNGCNYTNCCNATGAARAAY GARGARACNTCNAARYTNTCNGARTCNYTNAGYAAYTAYTAYAAYGARTCNYTNATHGGN CAYGTNYTNGGNTGGCARGCNGAYACNTTYGARAARCARGCNACNAARYTNTGGGARGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATHGAYGTNGCNYTNMGN MGNGARGGNATHCAYAAYYTNACNGAYGTNGAYYTNGAYCARGCNTGYGCNTGGMGNGGN YTNAAYCCNTAYGGNGTNGAYMGNCCNACNAARYTNGCNTAYYTNMGNAAYTGGACNGAR ATHACNGCNGAYGTNCAYGARTAYAAYGTNTCNYTNYTNYTNCAYYTNCCNATHYTNYTN AGYTAYTGYAARCCNTCNAAY--------------------------------------- ---------------------------TAYATHAARAAYGAYYTNGARAAYTAYMGNGCN GARTGYAAYMGNYTNYTNGGNTGYATHMGNGARGTNYTNAARGAYYTNAAYCCNATHTCN ATGYTNCARGGNGAYAARATHMGNYTNGCNAARATHTGYMGNYTNGTNAAYCCNGAYAAY AAYGGNGCNGCNTTYTCNTTYAAYGGNAARTGYTCNGCNAARGARMGNGARGGNATGATG GCNCAYYTNAAYAAYMGNYTNAARGAYAARATGAAYAARGGNAAYAARTGGGARGARGCN TCNGTNTGYYTNGARAAYAAYTAYGGNGAYACNGARAARACNACNCCNYTNMGNGAYATH TGYAARATGGCNGARAARGARGARACNATHTGYGGNAGYTAYAARACNCAYMGNCAYGTN GARCAYTTYATGAAYGARCARGCNGAYCAYYTNCAYTGYACNTGYACNCAYYTNYTNAAR GARYTNGARCARGAYCAYGAYCAYYTNCCNACNACNGCNYTNTTYGGNATHGGNGCNGGN GCNATHYTNYTNYTNTGYATHTTYTTYGGNGTNYTNTTYTGYTGYTGGMGNMGNAARMGN AAYAARAARAARAARAARMGNGGNCCNAAYGTNATHTAYYTNCCNGCNGCNAAYTCNGAY AAYTGYCCNGTNTAYCARGARATHTAY---GAYCARMGNCCNCCNGGNGTNGCNCCNAAR YTNCCNAGY---------MGNTAYGTNACNMGNCCNYTNCCNGGN---------AAYCCN TCNATGGAYGARAAYGARTAYYTNGARCCNGTNACNACN---------TCNAAYAGYTAY MGNTCNAARGCNCCNCCNCCNYTNCARATHAAYAAYCCNGGNTAY------GARYTNGAY GCNCCNCCNGARTAYAGYGARTCNACNATGTAYGARGAYGCNATHGTNATHCAR------ ------------GARGAYCAYAAYAAYGCNTAYTTYGAYCCNATHCCNACNCCN------ AARTCNGGNGAYAAYACNCARAGYTAYGAYACNYTNGAYMGNCAYGGNATGYTNGARGAR CARGARAARGAYAARCCNYTNGGNCCNGAYCCNTCNCARMGNACNAARAARGARGAYMGN GARACNGARTCNGARTAYTTYGARYTNGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TCNGAYMGNCARMGNAAYGAYAGYGARAAYTCNYTNCCNTTYGGNTCN CCNCCNAGYCCNTTYCCNYTNGTNCCNGAYCARGCNGTNAAYCCNATHCCNYTNAGYYTN GARGARACNTCNGAYCAYYTNGARYTNCCN------ATGAAYGCNTCNCCNAARCARAGY TCNMGNYTNGCNCCNGCNAAYACNTCNGAYACNTAYTAYTTYTAYCARGCNTCNACNGGN CARCAYATHTAYATGAAYTCNYTNAAYGCNCARTGYYTNGCNAARGARTAYGGNTCNYTN GARGAYAGYCCNGAYATHGTNAAYGCNTCNATHGTNGCNATHGARMGNATHTTYATGACN GARGAYGTNMGNAARMGNYTNMGNTAYYTNGAYCAYATHCCNYTNACNAGYGARATHCAY GTNGTNGARYTNACNATHAARCCNCCNACNGTNAGYAARGARACNYTNAARYTNTTYGAR GGNGCNTTYAAYAARAARMGNAARCARMGNCARCARAARGAYMGNGARGAYAARMGNMGN GCNAARAARTTYGARATHGARCARAARAARAGYTTYGGNATHTAYCCNGARGTNCARYTN CCNYTNGAYAAYGTNTAYCARTTYCCNACNCCNYTNTCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNGTNGTNGAYGTNGCNACNCCNYTNTAYGGNCARYTNCARAARTTYCARTCN AAYGGNYTNGCNGCNGAYATGATHACNTTYTCNGAYAAYTCNTTYAAYAAYGCNACNCAR CAYACNTAYAAYAAYAAYAAYAARTCNTCNMGNATGYTNAARYTNGAYYTNTCNGAYGGN GARMGNAAYATHCARGCNATHGARTAYACNCAYATHMGNTGYYTNAAYAARGAYYTNCCN TCNGGNACNAARATHYTNATHAARGGNCCNGTNATHTGYMGNMGNCARATGYTNYTNYTN CARGARGARAAYATHTGYATGYTNGGNGGNGARGTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNATHGAYACNTTYTTYAGYYTNCAR TTYCAYATHAGYGTNGTNAGYTTYGCNAARAARYTNACNCCNCARGCNTTYTCNYTNYTN ACNAARGAYAGYCAYTGYYTNAARACNYTNAAYYTNMGNGGNGCNAARCAYGGNATHACN AAYGARTTYYTNYTNCCNATHYTNTCNAAYAAYCCNMGNYTNGARAARGTNGAYATHAGY GGNTGYACNTCNYTNTCNGGNTGYGTNYTNTAYGCNATHGGNGTNAAYTGYCCNAARATH AARCARYTNATGYTNMGNGAYTGYGTNACNTTYACNGARGARAAYTTYYTNTCNTTYYTN TTYATGGARAAR------CCNGTNGARTAYYTNGAYYTNTCNGGNTGYTGGAAYATGGGN GAYGAYGTNYTNGTNAARYTNGTNCARAARAGYCCNAAYYTNAARCAYATHYTNYTNGGN AAYYTNTTYGGNYTNACNGAYMGNACNGTNTGYGCNATHGCNCAYTCNTGYCCNGARYTN ATH--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNAAYCARTCNYTNCCNATHYTNGARTAYYTNGAYGARGTNTAYCCNGARACNCCN YTNYTNCCNAARGAYCCNGCNGCNAARGCNCARGTNMGNGCNATHGCNGARYTNATHAAY AGYGGNATGCARCCNYTNCARAAYYTNAARGTNYTNCARAARGTNGGNGARACNAARATH GARTGGGCNAAYCAYTTYYTNACNCARGGNTTYCARGGNYTNGARGCNATGYTNAARAAR TCNGCNGGNACNTGYTGYTAYGGNGAYCARGTNACNYTNGCNGAYATHTGYYTNGTNCCN CARGTNGCNAGYGCN---CCNMGNTTYAAYGTNGAYATGAGYCARTTYCCNACNGTNCAR AARGTNAAYAAYCAYYTNGTNGARYTNCCNGCNTTYAARGTNGCNGAYTCNMGNMGNCAR CCNGAYACNCCNGARGAYATGMGNATHGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATGCAYGCNCCNGGNTCNCARGCNGCNCAYTGYYTNCCN GTNGCNGGNYTNMGNCCNACNACNGARGCNGAYGTNTAYMGNTAYAAYMGNGTNGTNCCN YTNTAYACNCCNGAYCCNTGYATHGGNCCNATGTCNAGYCARYTNATHTGYCCNCCNGAY TGYGGNCARCARMGNMGNAAYGAYYTNATGGARCCNGCNGGNMGNAARACNCCNGTNGAY ATGCARTTYCARTTYTAYCARCCNMGNCCNACNMGNCCNGARCCNAARCCNGCNTGYAGY TGYCCNGTNTTYGCNAAYMGNCARCCNTGYACNACNYTNGGNCCNATHACNGAYMGNYTN AAYTGYCCNTGYGTNAAYATGTCNGAYAARYTNAGYACNMGNGTNATHCARGTNAGYAAY ATHGCNCCNAGYTGYACNAARGAYCARYTNMGNACNYTNTTYGGNTAYYTNGGNMGNATH MGNGARYTNGCNATGTAYCCNCCNGARGGNACNGAYACNTCN---TCNGCNGCNMGNGTN GGNTAYATHGARTTYGARGAYTCNTCNACNACNGGNGTNTCNYTNCAYYTNAGYAGYACN GTNTTYATHGAYMGNGCNGTNYTNGTNGTNCCNGTNATGGAYGGNAARATHCCNGAYGAR AGYGCNGCNYTNCARYTNACNCCNTCNGCNGTNGCNGGNATGYTNCCNGGNCARCCNACN TGGCCNTCNAAYGTNGTNTCNCARGTNACNGGNYTNGGNGCNAAYCARGTNATHATGACN AAYGAYCCNMGNYTNACNTCNYTNGGNYTNCCNCARTAYCCNCCNYTNCCNGTNACNACN GAYCCNAGYAARATHGARGARATHMGNMGNACNGTNTAYGTNTCNGARYTNGAYGCNAAR GTNACNCCNGARATGYTNYTNTCNTTYTTYTCNCARACNGGNGARATHAARTAYATHMGN ATGGCNGGNGAYGARAAYGCNCCNACNMGNAGYGCNTAYATHGARTTYACNGAYCARMGN TGYATHGCNCARGCNYTNAGYTAYAAYAAYATHGTNTTYCAYGGNMGNACNGTNAAYGTN AARCAYGCNACNACNAGYATHGTNAARCCNACNCCNAARTCNGARGCNTCNCARMGNGAR ATHGAYGAYGCNATGAARAARGTNAARGARGCNTCNAARYTNATHTCNGCNGCNGCNAAY AGYGARMGNGARGGNTCNMGNTCNCCNAGYMGNAAR------MGNTCNAARTCNMGNGGN MGNAGYMGNTCNMGNTCNAARTCNMGNAARTCNMGNTCNMGNTCNMGN---GGNMGNMGN MGNAARAGYMGNTCNMGNTCNMGNMGNMGNTCNMGNTCNAARMGNMGNTCNCCNMGNMGN TCNMGNTCNCCNGTNMGNMGNMGNMGNTCNMGNTCNMGNNNNMGNGAYCCNCCNCCNGCN CCNCCNYTN------------------TCNMGNMGNMGNTCNMGNACNMGNTCNCCNGTN MGNMGNMGNMGNTCNMGNAGYAGYAGYAARGCNMGNCCNMGNAARTCNMGNACNCCNCCN AARTCNTAYAGYMGNAAYMGNMGNAGY--------------------------------- ------------------------------------------------------------ ------TCNGTNCCNGTNGGNGAYGAYGGNGAYAARTCNCCNGCNAARGGNAAYGGNMGN TCNCCNAGYCCNGTNAARATHAARAARMGNAGYCCNTCNCCNAARMGNMGNAGYMGNTCN AARTCNCCNAGYMGNMGNAARAARMGNMGNMGN---TCNMGNTCNACNTCN---MGNAAR MGNTCNMGNTCNMGNAGYGGNTCNMGNCCNMGNAAYMGNMGNGARAARAARMGNAGYMGN AGYMGNGAYMGNAARCAYGAR---AGYMGNAARAARTCNAGYMGNGAYAARGAYGARMGN AARAARGAR------TCNAGYTCNAARATHAARMGNGAYTAYGAYGARGARGARAARGGN TTYGCNAGYGAYCAYAGYGAYGARAARGAYACNAGYGARGCNGARGGNCCNAARGGNATG GAYTCNCCNCCNCCNGTNYTN---------GARAARGAYACNGAYCAYCARACNGTNGAY ATGGAYATGAGYGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATHATHGCNTGYYTNMGNGARGGNGGNGAYMGNTAY GGNAARAARATGGARGAYCARYTNGAYGCNYTNAARTCNGCNGTNGCNGARGAYTCNTAY GGNMGNTTYAARAGYACNGTNCARAAYTCNATGGGNCARGARYTNAGYTGGAAYACNGTN GCNYTNYTNTTYTAYGCNACNAARGGNGTNGTNTCNGCNGTNGGNAARAGYTCNCAYGTN GCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNCARCAYCARCARYTNAARYTNYTNGAYTTYTGYYTNCARGTNTGYTGYGGNATG GARTAYYTNAAYCARMGNAARATHATHCAYMGNGAYYTNGCNGCNMGNAAYTGYYTNGTN GGNAARGGNGAYGTNGTNAARGTNGGNGAYTTYGGNYTNGCNMGNGARGTNYTNACNGAY TTYGARTAYCARATGTCNGARCARTCNAARTTYCCNTTYAARTGGTCNCCNCCNGARGTN YTNCAYTTYMGNCARTAYAGYAAYAARTCNGAYGTNTGGTCNTAYGGNATHYTNATGTGG GARATHTAYTCNTTYGGNGARACNCCNTAYAARGGNAARACNAAYCCNGARGTNATHGAR TTYGTNGCNACNCARGAYAARMGNYTNAGYAARCCNCCNTCNGCNACNAAYYTNATGTAY GARTGGATGAAYMGNTGYTGGAAYAARAAYAAYCARGAYMGNCCNGAYTTYACNGARATH AARYTNAARYTNCARTCNYTNGGNTGYTCNGGNGAYTAYATHCCNATGYTNTTYAARGTN YTNTTYGTNACNGCNYTNTTYGCNGCNGCNTAYAGYCAYATGTGYYTNATHAGYCCNCAY CARMGNGGNTCNATGGCNGGNATHGAYAARGCNGGNTCNACNGAYTGYGTNYTNYTNAAR GGNCCNTGYGGNGGNMGNCCNAARTCNGGNACNCCNATHGARATHGTNGGNGGNTCNAAY TTYACNGTNACNTTYCARAARAAYYTNGAYCAYTTYAAYAARGCNAARCCNGGNAARTTY GTNGTNTCNATHGGNCCNGAYGGNAARTCNTGGACNGCNYTNGCNGCNGTNGCNGAYTCN GCNACNCCNTCNYTNAGYYTNTAYYTNGARGAYGTNACNYTNCCNGCNACNYTNGGNGAY ATGATHYTNCARGTNCARTAYGTNACNTCNAAYCCNAARGCNCCNGCNGTNTTYTAYCAR TGYGCNGAYATHMGNATHYTNGCNAAR---GCNMGNTAYMGNTTYATHCARYTNCARGTN ATHYTNCCNYTNYTNYTNATHATHYTNYTNCARTAYGAYYTNCCNGARATHACNGTNGAY TAYATHMGNAARTTYGGNCAYGTNGAYCAYCAYATHGARGARYTNACNGAYGAYGTNATH GCNAGYATGAAYGARACNGARYTNATHGTNACNGTNCAYAGYTTYYTNGAYAAYGCNGAY ATHYTNTGYMGNMGNAARYTNMGNATGGGNCAYGTNGGNGAYGGNGGNTGGGARGTNTGY GAYGAYCAYGAYATHMGNCCNCARGTNCCNTTYTGYATGGTNTAYTCNTTYAGYTTYGTN GCNGAYTAYGCNTTYGARGAYGAYGTNGCNMGNATHTAYAAYTGYGARGTNCAYTCNTTY AAYCCNAAYYTNCCNGGNCCNGAYTTYAAYMGNTCNTCNMGNGTNTTYGTNCAYCCNTAY GGNGCNGGNMGNAAYACNGARATHACNCCNAAYGGNAARGARYTNTAYACNYTNGARGAY ATHCARAGYATHYTNGGNCAYGGNGAYAARAGYATHGAYGTNATHAARATGGAYATHGAR AGYACNGARTGGACNGCNYTNAGYCAYATGACNACNACNGAYGTNYTNAARMGNGTNMGN CARYTNYTNGTNGARTTYCAYATHGGNTAYCCNCCNAAYACNTAYMGNYTNGGNMGNGCN ATHMGNATHYTNMGNTCNYTNAGYAARYTNGGNTTYMGNAARTTYTAYGTNCAYAARAAY CCNAARGGNTCNTTYCAYCAYCCNGGNTTYCCNGTNGTNMGNGCNMGNAAYTAYGARGTN CAYTAYATHAAYTCNAAYTTYGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GGNACNAGYACNAAYGTNTTYGGNTCNTCNACNCAR TCNGCNGCNCCNGGNAGYCCNACNCARTCNTCNACNGCNCCNGTNTTYGGNAGYAGYACN CARCARGCNCCNTCNGTNTTYGGNAGYAGYGGNGGNTTYGGNGCNACNAARCCNTCNGCN ACNAAYYTNTTYGGNGCNCCNGCNACNACNCARGCNTCNACNTTYGGNTTYTCNGGNCAR ACNTCNCCNTTYGGNGCNTCNACNGCNAGYTCNTCNACNTCNGGNTTYAAYTTYGGNCAR GCNGCNCARCCNGCNGCNAAYCCNACNGGNGGNTTYAAYTTYTCNGCNGCNTCNTCNCCN GCNCCNAAYCCNGGNGGNTTYAAYTTYGGNGCNCCNGGNTCNAAYGCNGCNCCNGGNTTY GAYTTYGGNGGNAGYCCNGCNACNCCNAAYATGTTYGTNCCNCARACNCCNGGNGCNACN CAYMGNCCNMGNGCNGCNACNMGNMGNGCNCCNMGNMGNGGNGCNMGNCARATHTCNCAY ATGATHGCNTTYATHGAYCARGARGCNTCNGARAARGTNGARGARATHGAYYTNAARGCN GARGARGARTTYAAYATHGARAARGGNMGNYTNGTNCARCARTCNMGNGTNCARATHATH GAYTTYTAYGAYAARAARATHAARAAYGTNGARYTNCARAARAARATHCARAGYTCNAAY ATGCARAAYAAYGCNMGNYTNGARATHYTNMGNAARAARGARGAYTAYGTNAARGARGTN YTNGAYGARGCNMGNGARCARYTNMGNAARAGYGCNMGNGAYAAYCCNGARGARTAYAAR CAYYTNYTNYTNMGNYTNATHYTNCARGCNYTNGCNMGNYTNGTNGARCARAARGTNAAR ATHMGNTGYAARCARGARGAYGTNCARATGATHAARAAYGCNATHCCNAGYYTNGCNAAR GARTAYAAYGAYGTNATGAARGGNAARTAYAAYGTNGARYTNACNGTNGAYGARGARAAR TTYYTNTCNTCNGARATHACNGGNGGNATHGARYTNCARGCNATGAGYGGNAARATHGTN GTNGTNAAYACNYTNGAYGARMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNGTNGTNTTYATHCARMGNAGYGARTGYTTYAGY GCNTGYCAYMGNYTNCAYAGYCCNTAYYTNAAYGAYGARCARAAYGTNAAYYTNTAYGGN AARTGYAAYCAYACNAAYGGNCAYGGNCAYAAYTAYAARGTNGARGTNACNYTNMGNGGN CCNGTNGAYCCNGARACNGGNATGTTYATHAAYATHGTNGAYGTNAARCARTAYATH--- ATGGCNGARAGYGAYCARCARTAYACNATHTAYGAY---GGNAAYCARCCNYTNACNYTN ACNGTNGGNAAYGTNAAYCARGGNACNGARGAYGCNCARGCNGTNCARGGNATHCARTAY ATHTCNCARGAYGGNATHCCNGTNACNCARYTNGAYTCNTCNGAYGTNATHCARGTNGCN CARGCNGCNGAYGGNACNTTYCARCARGCNGCNTCNACNTTYCARAAYATHCARGCNGCN GTNCARTCNCARGTNATGACNAAYACNGGNTCNGTNCCNATHGTNGCNGCNACNTCNCAR GGNGGNAAYATHYTN---CARTCNAAYGTNGTNMGNAAYGTNGCNCARGTNACNCARACN TCNCARYTNGCNCARCARGCNCARGCNGCNGGNTCNTCNMGNYTNAAYGTNACNAGYAAY GTNGGNCCNCARATHCCNCARATGYTNTTYYTNAAYCARGTNACNATHAAYGGNCARACN TCNTTYGTNYTNGTNGAYGTNGAYAAYAARCCNATHCARYTNCCNCARGGNATHCARGTN ATHAAYYTNCCNCAYCARCARATHTCNGGNCARTCNGTNCARATGCCNGGNGCNGAYACN GGNGAYGARCCNYTNTAYGTNAAYGCNAARCARTAYCAYMGNATHYTNAARMGNMGNCAR GCNMGNGCNAARYTNGARTCNGARGGNAARATHCCNAARGARMGNCARAARTAYYTNTAY GARTCNMGNCAYMGNCAYGCNYTNAAYMGNGCNMGNGGNTCNGGNGGNATHTTYGTNCCN CAR------TCNYTNGAYGTNGTNYTNGTNGTNGGNAARAARAARATHCCNGTNACNATH AGYAGYMGNCCNTCNGARGAYGAYGCNGCN---YTNTCNGTNGAYMGNYTNTGYCARACN ATHGARGARCAYACNAARATHAARCCNAAYGCNCARAARYTNATHTAYMGNGGNMGNACN YTNTTYAARAARTAYGAYCCNGARGAYGARTCNYTNAARAARAGYYTNYTNTCNYTNGGN ATHAARAAYGGNGAYMGNATHATGGTNTTYGGNAARGTNGCNCCNCCNAGYGAYGAYAAR GARGAY------GGNAGYAAYGAYGCNCARYTNATGAAYGTNYTNGAYMGNCAYCARGCN AARATHGAYGARATHTGYAARYTNTGYGCNGAYATGGTNGGNAARATHGGNGAYCCNGAR ACN---GTNGARGARTGGAARAARCAYAARAARTTYTTYYTNGGNCARTCNGARMGNTCN ATGCARGARYTNACNYTNYTNGAYGCNACNCCNGGNGAYYTNTCNCARMGNCARGARTAY AARACNMGNMGNAARGCNYTNGTNAAYAARYTNYTNGARAAYATHTCNYTNTGYGAYAAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGNAAYGTNTGYAARGTNTTYAARCARAAYGTNTGYGGN TTYGAYYTNYTNMGNGCNAAYGGNCARCAYTAYGTNTGYGAYGTNAAYGGNTTYAGYTTY GTNAARACNTCNAGYAARTAYTAYGAYGAYTGYGCNAARATHYTNGGNACNYTNGTNATG MGNGARTGYTGYCCNCARYTNCARATHCCNTTYCCNATGTCNTCNGCNCCNGARGAYATH CCNGTNGTNCARACNACNCCNGGNTCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ACNCCNYTN GCNATGYTNAGYMGNYTNYTNCCNGGNAGYAARAARGGNTCNGCNGARTGYGCNCCNGGN GTNACNCAYGCNCAYYTNYTNCAYGAYGARAARTCNGAYATHGARAGYACNCAYTCNGCN YTNCARCAR---------------------------------------GGNATHAARTCN GTN--------------------------------------------------------- ---------------------------------------------------------TCN TCNTCNTCNTCNAGYTCNTCNTCNAGYAGYGARTCNTCNGAYGAYGARTGGMGNCAYATG GGNAARAARGAYAARAARATGMGNAARAARTGGAARAARCARATGAARAARGGNATGATH CCNMGNGGNACNATGGCNCCNTGGCARGGNGGNCCNATGTGGGCNCCNCCNAGYAAR--- ---------GGNAARAARGGNAARTCNGGNAARAARGGNAARGGNTAYCCNAARACNGGN GGNTAYCCNGCNCARCCNGGNTAYCCNGGNACNGGNTAYCCNCARGCNCCNGGNTAYCAR CCNCARAAYCCNGCNTAYCCNCCNCCNCCNGGNGTNTAYCCNGGNGGNCCNGCNCCN--- CCNCCNCAYGCNGGNTAYCCNGGNGGNCAYGCNCCNCCNCCNCARAAYTAYCCNCCNGGN GCNCCNCCNCCNGGNGGNTAYCCNGCNGGNAAYTAYCCNCCNCCN------CCNCCNGGN CARTAYGCNCCNCCNGGNCARTAY---GCNCCNGCN---------TAYGGNGCNCARGGN GCNCCNGCNGGNCCNTTYCARGTNCCNCCNMGNGGNGCNTAYCCNCARCCN------GGN TAYCCNCCNCAY------------------------------------------------ ------------------------------------------------------------ ------------GTNYTNAARGARYTNGARTCNGCNGCNGCNGARMGNTCNACNYTNAGY CARGARAARYTNACNYTNTCNGARMGNGCNGARGARYTNCARGTNGCNYTNCARGARATH GARGARAARACNAARACNATHCARGARGAYAARTCNACNACNGARGTNMGNYTNMGNGAY AAYYTNGARMGNYTNGAYCARYTNGARTTYGARAARACNATGATHGCNGAYCAYGCNTCN GARYTNGARGGNACNATHAAYGAYYTNGTNTCNCARAARGARYTNACNGARAARGARYTN AARGARGARATHMGNGCNMGNATHTCNGCNGARGAYMGNYTNAARGARGCNGARACNTCN YTNAAYTCNYTNGAYGARGCNGTNAARACNCARTCNCAYMGNATHGARGARGGNGCNAAR GCNGARATGACNGTNAAYGTNMGNAARYTNAARCAYTTYTTYGARGAYYTNGCNGARGAR GCNAARATHACNGGNGAYAARCCNATHGTNYTNMGNAAYGGNYTNGTNGCNMGNAARACN YTNGCNMGNMGNGCNAARACNATHMGNTAYGARAGYMGNMGNMGNTCNTCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TGYGARGAYATHATHGAYGGNGTNATHCCNYTNTCNAARGAYGGNYTNATHTGY ATHAARAARGGNMGNTGYTAYAARCCNAARTGYACNGTNGGNAARTTYGAYGTNAARTCN AGYTAYTGYCCNYTNTCNGAYTTYTAYGCNYTNCCNGARAAYYTNTTYGARAAYCCNGAR GAYMGNMGNCAYCAYMGNCAYCAYYTN--------------------------------- ---------------GGNMGNTTYTAYAAYACNAGYTAYYTNGGNYTNAAYACNGGNAAR GCNTAYYTNMGNAAR------------------ACNACNCCNAARAARGCNAAYAGYGCN CAYTTYCAYMGNCCNCCNAAYTTYACNTAYGCNAARGAYGCNCCNACNTTYYTNAARAAR AARGGNACNGGNATGGCNGCNYTNACNTCNGTNACNMGNGTNGTNAARGTNMGNMGNAGY TCNTCNCCNGGNGAYYTNMGNAAYCARGARGCNGTNMGNYTNAGYATGTTYCCNGGNGCN AARCCNMGNCARCCNGAYGARCARGARACNATHGARMGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GCNATH GGNTAYGGNAARCCNCCNCARGAYGARATHTCNATGACNGTNATHATHATHATHTCNGTN GGNYTNGGNYTNCCNGTNYTNATGTGYATHTTYGGNGGNATHTAYACNATHGTNMGNTCN GTNMGNAARAARTCN---TCNCARTAYGARGCNATHAAYGGNTCNGAYTCNATHAGYMGN TCNMGNCCNGARGTNAAYATHAARGTNYTNGARTTYGTNYTNGCNATHTTYGCNTTYGCN ACNACNACNAGYCCNTCNACNTCNACNACNTTYACNGTNAARAAYTGYAGYATHTCNACN AAYTAYACNAAYAAYGGNCCNGCNTCNATGACNTAYTCNTAYAGYTAYCCNTAYGAYYTN GARAGYGTNTGYTTYAARAAYGTNYTNTGYCCNAAYAGY---YTNAAYYTN------AGY ACNTTYTGYYTNYTNGAYGGNTCNCARTCNTCNGCNCARTTYTAYGTNTTYGTNGGNGTN ATHGTNTTYYTNTAYTGYYTNGGNGCNATHATHYTNTAYGTNTTYTTYGAYGARYTNTAY MGNMGNAAYACNMGNGTNGTNYTNGCNGAYTTYYTNATHTCNGTNGGNYTNATGYTNYTN TGGYTNATHGCNTCNTCNGCNTGGGCNTCNGGNYTNAAYGAYGTNAARYTNTAYACNGAY CCNAGYGAYGGNGARATHTTY---AARAAYGTNCCNGARTGYYTNCCNGAYGGNGCN--- TGYTAYACNTCNAARGARGGNAAYTTYGCNAGYYTNAAYGTNTCNATHATHTTYGGNTTY YTNAAYTGGATHGTNTGGATHGGNAAYYTNTGGTTYYTNTAYAARGARACNCCNTGGTTY AARGTNCARGCNAARCCNCCNACNGARCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTAYAAYGGNATHGGNYTNCARACN CCNMGNGGNAGYGGNACNAAYGGNTAYGTNCARMGNAAYYTNGCNTTYGTNAARGGNAAR AARGAYMGNGTNGAYTAYAARAAYGARGAYGARYTNMGNAARYTNGARCARTCNATGCAY AARCARCCNAAYCARGARATHYTNGAYCAYGARMGNAARMGNAARGTNGARYTNAARTGY ATGGARATGCARGARYTNATGGARGARCARGGNTAYACNACNAARGARGTNATGGAYAAR GTNAAYATGTTYMGNAARATGYTNATGGCNAARGARGGNGTNTCNGAYACNACN---ATH GARAARGAYGARCAYGGNMGNCCNATHGCNAARGARACNCAYCARYTNGCNGARGCNAAY CARGCNAARAAYGAYAARYTNAARGARGCNTTYGGNYTNTCNGAYTAYGTNGARGGNAGY GCNTTYGAYCCNGAYMGNAARGCNAARGARGARCARGCNAARYTNYTNGCNYTNGCNCAR AARAARTAYAGYATHGTNAAYAGYTCNGAYGARGAYGAYGAYAAR---GAYAGYTCNCCN NNNCARGARGARAARAARAARAARTCNMGNCAYGAYGAYGGNTCNTCNCCNGARMGNAGY AARGARAARMGNAARAARAGYMGNAARCAYAGYAARMGNGAYMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYTTYCCNTCNTCNTCNYTNCCNYTNCAY TCNGTNGCNMGNGARMGNTCNACNYTNATHMGNAARYTNGARMGNCCNYTNACNCARATH YTNMGNAAYTCNCCNTTYTCNTCNAARGGNACNYTNGTNTCNTCNYTNGARGTNATGAGY AGYYTNCARAARCAYATHYTNGAYYTNACNCARMGNYTNCAYGGNGTNGARAARGARMGN MGNYTNYTNYTNTCNGAYYTNAGYAAYYTNMGNCARCARATHGGNGAYGARAAYTCNTCN AAYYTNAAYACNTCNGAYAARCAYGARTCNGGNAARGGNACNAARTAYGTNGCNATGGAY AARTTYGARAARGTNTGYYTNGARYTNTCNGGNGCNYTNMGNMGNGARCARAARGCNCAR GTNYTNYTNCARGARCARAGYAAYCARYTNGCNGARYTNACNACNMGNYTNGAYATGTGY GCNTCNGAYGGNGTNACNAARGARCARAGYYTNGTNAAYATHCARGARGGNYTNTCNGAR ATGCARGGNCAYYTNMGNYTNAARGAYCARAAYYTNMGNCARATHAGYAARCARYTNGCN CAYATGGARTAYCARAARGARACNATHGARAGYAAYYTNCARGAYGCNGARAAYGCNYTN MGNACNGCNGCNAARGAYAARGARATHYTNGCNCAYTAYATHCARAAYGTNGGNAAYGCN YTNCAYTCNGCNAARAARCARTTYYTNATHYTNCARGARGCNCCNCCNYTNTCNAARCAR CCNTCNYTNTCNGGNYTNYTNYTNGAYGCNGAYYTNATHCCNYTNGAYATHGGNAARTCN GGNCCNGARYTNATHTCNYTNCARAAYYTNGTNGGNGGNTTYGTNGAYGCNCARCAYCAR GCNGTNAAYAARATHMGNTCNYTNGARGARGARATHACNTCNCAYMGNAARCAYATHGAR TCNYTNAARCARGARYTNAGYAAYGCNGTNCARMGNGARTTYCAYAAYCARYTNAAYTCN CCNTCNGAYGGNGGNTTYYTNGARYTNACNGAYCARGARGAYGAYACNATHACNYTNAAR GARGAY------------GTNGGNGAYATHTCNAGY------------GARGGNCCNACN CCNMGNAARYTNACNCCNCCNATHYTNAAYTCNAARAARACNGCNTTYCAYTCNGTNAAR TCNAAYAGYGGNYTNACNCARACNGGNATHCCNATHGGNGCNGTNGTNATHAAYCARYTN ATHACNGCNTAYGTNAAYCCNGAYAAYYTNYTNCCNGAYGTNATGYTNGGNCCNTCNCAR TTYTAYACNCARGCNCARGTNYTNGAYMGNGTNCCNAAYATHYTNYTNYTNYTN------ ---------------------------------------------------ACNACNACN ATHGARGAYCCNTTYAARGAYTCNGAYTTYATHCAYGAYCAYCAYATHTAYTAYAAYACN ---------AGYGCNGARAARGARCARGTNGAYTAYGTNGAYYTNTCNTCNGCNTCNMGN CAYGARGTNYTNTCNAGYAGYCAYMGNGTNGCNGCNGTNATHTCNYTNMGNTTYAARTTY CCNTTYTAYGGNCAYCCNATHACNAAYGTNACNGTNGCNACNGGNGGNTTYYTNTAYATG AGYCCNTTYYTNCAYCARTGGYTNACNGCNACNCARTAYATHGCNCCNYTNATGGCNAAY TTYGAYCCNTCNATHAGYAGYGAYTCNCAYATHTAYTAYYTNAGYGARGCNGARMGNTTY ACNATHGARTGGMGNGARGTNTTYYTNAARGAYCARCARGAYTTYGGNAAYTTYACNTTY CARACNTCNYTNCAYYTNGAYGGNAARATHACNTTYGCNTAYAARCAYATHCCNGTNGAY GTNAAYAARATHTCNAAYGTNAAYCAYCCNGTNAARATHGGNYTNTCNGAYGCNTAYTAY AAYGAYACNTTYYTNCCNCARTGGGGNATHMGNMGNMGNACNATHTAYGARTAYCAYCAR GTNAARYTNMGNAARAGYTTYGCNAARACNGGNGCNGTNATHMGNGTNAAYCCNYTNCCN ACNTGYAAYATHYTNGARGAYTGYAAYTCNTGYGCNCARCAYGARGGNGTNGAYTTYAAY TGYAARTGGTGYAAYACNATHGGNMGNTGYTCNGAYGGNYTNGAYTGGTTYMGNCARCAY TGGGAYAARTAYGAYTGYMGNGCNGTNAGYYTNAAYCARGARAARGAYTGYGCNGGNYTN CCNCCNCCNATHAARCCNATHGTNACNCCNATH---CCNCCNYTNGARACNAARAARGAY TGYTCNGGNGGNAARTGYGAYAARAGYTCNAARGTNCCNGCNGCNGTNATHGTNGTN--- GTNATHYTNYTNATHYTNGGNYTNGTNGCNGGNGTNGGNGGNTGGACNTAYTAYGCNTAY ACNCAYCCNACNTCNMGNTCNGGNATGTGGYTNATGGARCAYMGNCCNAGYCARATHAAR GCNAARATHAARTTYTGGAARAAYAGYAGYAAYAGYGCNGCNAARTAYMGNGCNGARTCN GARGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNAGYYTNYTNTAYGCNGARCCNYTNTAY GGNTGYAARTGYTCNGCNTGYGARGARGCNATGAGYAGYGAYATHCAYTCNGCNYTNAGY GCNGCNYTNAAYGARAARYTNCARAARTTYCCNATHAGYCCNACNGTNYTNGTNCARYTN GGNGAYCAYGTNGTNACNAARGGNGAYATGACNGCNMGNATHMGNTAYATHGGNCAYYTN GAYAARATHGGNCARCCNAAYATGGTNTTYGCNGGNYTNGARYTNGAYGCNCCNGTNGGN CAYCAYGAYGGNTTYTTYAAYAAYAARMGNTAYTTYTTYTGYCARAARGAYCAYGGNATG TTYATHCCNYTNCAYGAYACNYTNTGYAARGTNAAYAAYAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYGTNGCNGARYTNTCNAAYGTNTGGACNCARAAYYTNACNAARAAR CCNCARTGYATHAARGCNYTNAGYMGNAARGAYGTNAARATGTTYAAYYTNTTYTGYCCN ATGAGYGGNATHGAYTCNGARGCNTGYTAYGGNYTNTTYAARYTNTTYGGNTGGCCNYTN ATHGCNGGNGGNTTYGTNAAYAARMGNATHYTNMGNGAYTCNMGNGGNGARTTYCAYAAY TCNAAYCARTCNTGYYTNGTNTCNAGYYTNGCNTTYTGYGGNGARAAYGTNCARGTNGCN TCNGTNATHYTNMGNAGYTAYATHCARAARGARGAYGARGTNAARAARGTNGTNMGNAAY YTNAARGAYTTYAAYTTYCCNYTNGAYAAYGCNTTYGGNYTNATGTAYGCNTGYGTNGGN MGNGGNTAYCAYYTNTAYCAYAARCAYGAYGTNGARGTNGARGCNTTYAARAAYCAYTTY CCNACNGTNCCNYTNATHGGNTTYTTYGGNAAYGGNGARATHGGNTGYCCNTTYCCNCAR CCNGGNYTNATGCCN---------GTNTCNAARGTNCCNAARCCNGAYMGNATGYTNMGN AARATHAGYAARGAYYTNTCNTCNGCNCARATGAARMGNCAYYTNTCNGARATGATGCAR TTYYTNGARAAYTAYMGNAGYAARCAYGCNCCNAARATHYTNCAYTCNTAYACNACNGTN ATHTGYYTNATHGCNYTN------------------------------------TGGYTN TCNCARYTNTTYGGNAAYGGNCARATHCCNGARTTYGARAARAAYCARCARACNATHGAR GTNYTNCAYAARYTNTCNGCNATHTGYYTNTCNAAYGAYAGYAAYACNCARYTNTAYATH GAYGAYYTNAARMGNAARGTNGARGARTAYGAYGCNGAYGCNCAYMGNYTNGARGGNGTN YTNGGNMGNYTNYTNATGGGNCAYAGYAGYTAYTCNACNAARGCNYTNTCNCAYACNCAR GCNYTNGCNCARACNGGNGCNTCNYTNGGNGTNAARAAYGCNTCNAAYGCNAGYTTYATG YTNTCNYTNGGNGARYTNCAYTCNGAYATGGAYGCNATHACNACNAARATHCARGAYGAR TGYAARGCNACNCAYAARYTNTCNAAYGARATHCARGGNATHYTNGTNAARCAYAGYACN YTNAARAARGCNYTNGARGARYTNGAYAARAARGCNTCNAARGAYGTNGCNCARATGAAR AARMGNAARCAYGARATHGARAARYTNAARGARTCNGAYGCNGTNTCNGARCARAARYTN ACNAARYTNAARGCNGARYTNGCNAARTCNACNYTNMGNGARTCNTAYTGYCAYGARAAY YTNGTNCARAARAARGARAARYTNGAYAAYYTNCARAAYGARYTNGARCCNYTNCARGCN AARYTNCARTCNTAYGCNACNYTNCCNCCNAAYGTNGCNGARGTNAARGTNATGATHGCN CARYTNAAYATGGARYTNGAYGARYTN--------------------------------- ------GTNATGGARTAYTGYTCNACNTCNATHGGNATHGTNYTNYTNYTNTCNYTNTGY GCNTCNGTNGAYTCNTTYATHGTNTTYTCNCCNGGNGTNTGYCCNCARGTNGAYGTNAAR CARAAYTTYAAYATHTCNGCNTAYGARGGNMGNTGGTTYAGYTAYCARAAYTTYGAYGCN CCNTAYCARTTYGGNATGTCNTGYGTNACNGCNAAYTAYAARYTNYTNCCNGAYAAYACN ATHCARGTNATHAAYGARGGNTTYAGYGCNATHMGNGTNTTYGGNATGTAYYTNAAYMGN MGNCCNATHCARGCNGTNGGNGCNGCNMGNGTNYTNGAYTGGTCNGAYCCNGCNMGNYTN MGNGTNGCNTTYGGNCARCARCCNAGYATHGGNGCNCCNAARCCNAAYTAYCARGTNATH GAYACNGAYTAYAARACNTAYAGYYTNGTNTAYTCNTGYAGYAGYYTN---ATHGTNCCN TTYAARYTNGARGGNGCNTGGATHYTNACNMGNACNMGNGGNGCNMGNCCNGTNAAYACN GARGARYTNAARAAYAARYTNGCNTCNTAYGGNGTNAARATHAARTAYTTYAARATGGTN GAYCAYAAYAAYTGYGARGGNGARGCNGAYATHACNGCNATHACNGGNTAYGAYCARGAR TTYGAYGGNGARYTNGAYGGNGARGGNACNAAYGARGTNCARGCNATHGARGCNGAYAAY AAYGARACNMGNAGYGCNGAYAARAARAARAARAARAARAARAARAARAARTGGYTNTGY ATHTGYYTNACNAAYTGYAARTAYGAYGTNGTNMGNMGNACNGCNMGNAARTTYGGNTTY AARGARGTNCARGAYGAYGARGAYTGGACNYTNTAYTGGACNGAYTTYTCNGTNGCNYTN GARMGNGTNATGGARATGAARAAYTAYCARAARATHAAYCAYTTYCCNGGNATGAAYGAR ATHTGYMGNAARGAYATGYTNGCNMGNAAYYTNAAYMGNATGCARAARYTNTTYCCNAAR GARTAYAGYGTNTTYCCNAARACNTGGTGYYTNCCNGCNGAYTAYGGNGAYTTYCARGCN TAYACNMGNCARAARAARAAYAARACNTAYATHYTNAARCCNGGNTCNGGNTGYCARGGN MGNGGNATHTGGGTNACNAARAAYCCNAARGARATHAARCCNCAYGARCAYATGATHTGY CARGTNTAYATHAGYAARCCNTTYYTNATHGAYGGNTTYAARTTYGAYYTNMGNATHTAY ACNYTNGTNACNTCNTGYGAYCCNYTNMGNATHTTYGTNTTYAARGAYGGNYTNGCNMGN TTYGCNACNAAYAARTAYGTNGARCCNAGYCAYAAYAAYACNGAYAAYGTNTAYATGCAY YTNACNAAYTAYGCNATHAAYAARCAYAGYGARGAYTTYATHMGNGAYGAYGARGCNGGN AGYAARMGNMGNATHAGYACNATHAAYMGNTAYYTNAAYGARAARGGNTAYGAYGTNGAR MGNATGTGGGCNGAYATHGAYGAYGTNATHATHAARACNTGYATHTCNGCNCAYTCNGTN YTNAARCAYAAYTAYMGNTCNTGYTTYCCNAAYCAYATHMGNGGNTCNGCNTGYTTYGAR ATHYTNGGNATHGAYATHYTNYTNGAYAARAARYTNAARCCNAGYATHYTNGARGTNAAY CAYTCNCCNAGYTTYACNACNGAYGCNGAYYTNGAYMGNGARATHAARGGNACNYTNGTN TAYGAYACNYTNMGNYTNATHAAYTTYGGNGCNGTNGAYMGNMGNAARTGYYTNGAYGAR GARMGNAARMGNATHAARGAYMGNYTNYTNGGNAARTAYGTNAARAARGARACNAARGAR GARYTNGARGCNGCNCARACNCARTAYATHGARCARYTNGARMGNTAYGARGAYGGNCAY YTNGGNAAYTTYMGNMGNATHTTYCCNYTNCCNGGNACNGARAARTAYGAYAARTAYTTY CAYAGYAGYGGNACNYTNTTYCARGARACNGCNGCNTTYMGNGCNMGNCARGARYTNGCN MGNCARCARMGNGARGARATHYTNMGNAARAARGARAARAAYGARATGATGYTNAARGGN AARGCNAARAARGAYGGNYTNMGNCCNGARAGYCCNGGNMGNAARMGNMGNYTNAGYCAR MGNCCNACNYTNCCNYTNMGNCAYATHACNCARMGNACNCAYGAYTCNAARGAYTGYGAR CCNGTNGAYACNACNAARCCNCARGAYATHGTNGARGAYGARGARYTNGARMGNYTNTCN GGNYTNYTNCARMGNGAYAAYYTNGTNMGNGGNYTNGGNATHGTNGARCAYGTNTAYMGN YTNYTNCAYTGYACNCCNGGNACNATGGGNGTNGTNMGNCARGAYCARMGNTCNAAYCAR GGNGGNGTNGGNCARAGYCAYACNYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATHTAYGTNCAYCCNTTYTAYACNYTNATGCCNAAYYTNACNGGN GAYATHGCNYTNYTNAARYTNMGNGCNCCNGCNMGNAAYACNACNGCNGTNMGNCCNGTN GCNYTNGAYGTNGARMGNCARATHGCNCCNGGNACNGTNTGYCARGCNGCNGGNTGGGGN CARCAYACNGCNGAYGARTAYGGNGARCCNCARTTYGGNAAYGGNACNATGGTNCCNCAY GTNATHAGYGTNAARYTNGCNTCNCARACNTCNTGYGGNAAYGCNTAYGCNMGNCARTGG CCNYTNGTNGAYGCNTCNGTNATGTGYYTNTAYTCNGAYGARAARAARGAYACNTGYAAR GGNGAYTCNGGNGGNCCNYTNATGTGYMGNGAYGTNAAYGGNGAYYTNGTNYTNTCNGGN YTNGTNTCNGTNGGNGTNAGYTGYGCNCAYGCNGAYTAYCCNGGNATHTAYACNMGNGTN TCNCAYTAYMGNAAYTGGATHTGGGARATHATHAAYACNCAYTCNACN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TGYAGYMGNCARAARCCNTAYMGNTTYYTNATHCARGGNYTNGAY GCNGCNGGNAARACNACNYTNYTNTAYMGNYTNAARYTNGGNGARATHGTNACNACNATH CCNACNATHGGNTTYAAYGTNGARACNGTNMGNTCNGCNAAYGGNATGGARTTYGAYGCN TGGGAYGTNGGNGGNMGNGAYAARATHMGNCCNYTNTAYMGNCAYTAYTAYCCNAAYACN GAYGGNYTNATHTAYGTNGTNGAYAGYTCNGAYMGNGARMGNYTNGGNGAYGCNYTNGAR GARYTNGAYAAYTAYATHYTNAARTGYGARGARYTNTCNAAYATHGTNYTNATGATHYTN GCNAAYAARCARGAYYTNAARGCNGTNATGAGYCCNGCNGARATHGARGAYGARYTNCAR AARCARTGYCARATHGGNTTYGGNATHACNGTNTTYGTNATGCCNTGYAGYGTNGTNAAY GAYTCN------TCNATGTAYGAYGCNTTYGARAARTTYGCNACNATHGTNACNGARAAR AARCAR------------------------------------------------------ ------------GGNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AGYGGNYTNATH GGNMGNAGYTTYGCNATGYTNTTYGCNAGYGTNGGNTAYGAYGTNATGATHTAYGAYYTN GCNCCNGARCARACNGCNGCNGCNAARGCNGAYATHAARAGYCARYTNGCNGCNYTNCAY GARCARGGNYTNYTNMGNGGNAARYTNGGNCAYGAYGARCARTAYAAYAARATHTCNACN ACNGARAGYYTNAGYGAYTGYGTNCAYGGNGCNTTYTTYATHCARGARTGYGTNCCNGAR MGNYTNGARATHAARMGNTCNGTNTGGTCNCARATHGAYAARATGGTNGAYGGNAGYGTN ATHATGTCNACNTCNACNAGYGCNYTNYTNCCNTCNACNATHTCNGARGGNYTNACNCAY AARAAYMGNTTYATHGTNTCNCAYCCNACNAAYCCNCCNTAYTAYGCNCCNGCNACNGAR GTNGTNCCNGCNAARTGGACNGAYGARGARGTNGTNAARAARACNGTNGARATHYTNAAR GARATHGGNCARGTNCCNATHATGGTNAARAARGARGTNAAYGGNTTYGTNYTNAAYMGN YTNCARTAYGCNATHATGGGNGARGCNTAYMGNYTNATHMGNGAYGGNGTNGTNAGYGCN ACNGAYYTNGAYYTNGTNATGTCNGARGGNYTNGGNGCNMGNTAYTGYTTYATGGGNCCN TGGGARACNGCNCAYYTNAAYGCNGARGGNATGATGGTNTAYGGNGARMGNTAYGCNGAY ATGATHYTNGGNATHCARAAYAGYTTYAARGARCCNGARMGNATGGARGGNGARACNYTN CARGCNATHGARAAYGARATGATHCARGTNGCNGGNCCNYTNAARGAYYTNGAYCARMGN MGNCARTGGMGNGAYAARMGNATGGTNGCNYTNGCNAARYTNAARGCNCARATGAAYGTN GARGAYAAYAARGAYGTNGTNYTNTCNGTNGAYACNACNGGNGTNGTNGGNCARAAYYTN GAYGARGTNAARGGNMGNATHAGYGARATGYTNCARCARYTNCAYCCNAAYATHCAYGAY YTNCAYYTNGGNGTNATHAGYCAYGGNAAYCARGCNGARACNGTNCAY------------ ---AAYTCNGAYYTNACNMGNGAYYTNGTNGARACNGTNAARTTYGTNAAYTCNATGGAR GARAGYGARAGYMGNGAYAARCCNTCNMGNTAYGAYYTNGCNYTNCARCARGCNMGNACN YTNTCNTGGMGNGARGAYAGYCARMGNYTNATHGTNGTNGGNGGNGGNTCNTTYCCNAAY GAR---GAYGARGAYGARGAYGTNGAYMGNGTNGAYTGGCARTAYCARGCNGARCARYTN TCNAARATGAAYATHGCNATHTAYGCNGTNCARYTNTCNAAYGARGGNGAYAGYTCNGAY TTYTTYAGYAARYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TGYCCNATHTGYYTNGCNGAYTTYGARGARGGNGARYTNAARMGN ATHYTNCAYTGYCARCAYGARYTNCAYAARCARTGYGTNGAYACNTGGYTNAARACNAAY GCNACNTGYCCNGTNTGYMGNGARAAYYTNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARGGNCAYYTNTTYTGYAARGARTGYGTNGTNMGNTCNACNGARGCNGCN TTYGGNGARATGAARACNMGNTTYCCNTGYYTNACNGGNGARTGYGARCARGAYATHCCN YTNAGYACNYTNCARMGNATHATHCCNGCNAAYYTNTTYTCNAARATHGTNAGYMGNYTN CARGARGARGARGTNYTNAARGCNGAYATHCCNGAYYTNGTNACNTGYCCNTTYTGYCCN TTYGCNACNGTNATGCCNGAYYTNGARGAYAARATHYTNMGNTGYYTNAAYCCNGARTGY YTNAARGARTCNTGYMGNYTNTGYMGNGARGARAGYCAYATHCCNYTNMGNTGYGARGAR GTNGARAGYMGNGCNGGNGTNAAYATGMGNACNTTYATHGARAAYAARGTNGCNGARGCN GTNATGMGNAARTGYCAYAARTGYAGYAARAARTTYYTNAARGAYTCNGGNTGYAAYAAR ATGACNTGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNACNTGGTGYMGNAAYATHACNYTNACNMGNYTNYTNMGNCAR GAYGAYGCNGAYGAYGGNGCNGCNGARGTNGARGAYTCNAARCCNAARMGNAARGTNGTN GAYGTNGARACNAGYATHMGNTAYATHAAYAGYCAYGCNTTYGTNGARGGNTAYGGNGAY AARCCNGTNTGGTTYCAYTAYMGNMGNAAYTTYAARGGNACNGTNATGCCNCCNACNMGN AARMGNTGYATHMGNAARGGNGARGTNTCNACNGCNAGYCCNTGYCCNGTNTGYMGNGAY GARTAYYTNATHYTNGAYGCNAARAAYACNAARYTNYTNAAYCARTTYATHTCNCCNTAY ACNGGNGARYTNYTNGAYTCNATGAARACNGGNYTNTGYCARCARCARCARAARACNYTN ACNYTNGARGTNATGMGNGCNTGGGAYCARGGNTAYYTNGARATGAARGTNCCNTTYMGN TCNTAYGAYTAYGAYGAYTAYAARAGY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TTYGARACNAAYGGNGCNATHAAR CARCCNGCNGAYTTYGCNAGYTAYYTNYTNGCNATHTTYATHGGNAAYYTNYTNYTNTAY TGYYTNTTYTAYGTNATHATGAARYTNYTNAGYAARGARMGNATHAGYCCNYTNGTNGCN TGYGTNATGYTNATHTCNYTNYTNTCNTGGGGNGGNTCNYTNTAYTTYTTYTTYCARCAY GTNACNACNTGGCARAARACNCCNGCNGGNTCNMGNGARGGNAAYMGNCCNTGYATHYTN TTYGAYTTYTAYGAYTCNCAYGAYGTNTGGCAYTTYYTNTCNGCNTTYAGYYTNTTYTTY TCNTTYATGATHYTNTTYYTNYTNGAYGAYGAYGTNYTNYTNAARCCNMGNAAYGARATH CCNGTNTTY--------------------------------------------------- ------------------------------------------------------------ GGNGARGAYMGNATGGAYGTNTCNCARCCNGARGGNACNGARGAYAGYMGNGGNATHGGN CARTGGAARACNGCNGARCARCARTAYATHGCNTCNGCNGTNYTNGCNCARAARAGYGAR MGNGARGCNYTNAARGARGTNGARGARGARMGNGAYAARYTNGTNGARGAYAARACNACN YTNCARAAYTCNGTNGARTCNYTNGARCARGARYTNGTNAARAARACNGAYYTNYTNGTN GCNGARMGNGARATHGGNGCNGCNAARGAYAARMGNYTNMGNCARYTNGCNGAR------ GAYYTNTCNYTNTCNAAYAGYGARGGNYTNGAYGARMGNGTNAARGAYYTNCARGARMGN YTNGCNGTNYTNGCNMGNGARGGNGARGARAARGARAARMGNATHAAYTCNYTNGARAAY GARYTNMGNTCNACNAARGGNYTNYTNCARCARAARGARGGNCARYTNAARGCNYTNGCN GCNGCNTCNGCNGGNGGNGGNGAYGCNCCNAARTCNAARACNTGYATHYTNATG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNTTYAARAGYGAYYTNTCN YTNGARAARYTNTAYCCNAGYTCNAAYACNGAYTTYYTNMGNAARCCN---GARCCNAAR CARGCNTCNACNGAYACNGAYGGNTTYTCNGGNTAYATHCCNGTNGARCARATHGARATH ACNCAYAAYMGNAGYAGYGGNCCNGGNGGNCARAAYGTNAAYAARGTNAAYAGYAARGTN GARGTNMGNTTYCAYGTNGARTCNGCNGAYTGGATHCCNCARTGGATHMGNCCNMGNYTN GTNGARCARGARCARAAYMGNATHACNAARGAYGGNTTYYTNGTNGTNAARTCNGAYATG ACNMGNAARCARATGYTNAAYCARGCNGAYTGYYTNAAYAARYTNMGNAAYATGATHCAY AARGCNTCNGTNYTNCCNAARGARYTNACNCARGARGARATHAARATHATGGARCARMGN YTNATGAARGCNAARTCNGGNATHYTNAARGARAARMGNAAYMGNTCNYTNYTNAARAAR TCNMGNGGNGCNCCNGARYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TAYYTNAARACN YTNATGAARGAYGCNAGYGTNTCNGARTGGYTNTCNTGYATHATHMGNYTNAARAAYAGY GTNATHGGNAGYAAYMGNGARAARACNAARTGYATHCARYTNGGNATHGTNCCNMGNYTN YTNAAYTGGATHGARGAYGAYAAYTGYCCNGCNGAYYTNAARACNGARTCNGTNATHGTN YTNGGNAGYYTNGCNAARGGNGGNCAYGAYACNGTNAAYCARYTNGTNCARTTYAARGTN GTNCCNACNYTNYTNMGNTCNYTNTCNAAYTTYGAYYTNAARTAYTGYGARGCNGTNYTN MGNTGYYTNMGNTCNATHTTYATGGARAAYACNGAYTGYATHGAYYTNYTNTAYCARGAR TCNAAYTTYGGNGCNTCNTAYATHCCNACNTTYYTNGCNATGGCNCARCARTCNGARATH TGYCARGARTGYGTNGCNAAYATHYTNGTNTGYGCNTGYAARACNAARGARCAYCARATG TGYYTNYTNAARAAYCARGCNATHTCNATHYTNACNCCNYTNYTN---CARTCNAARAAR TAYAARATHCARATGCCNACNYTNAARTGYTTYGCNAARATGACNCAYMGNAAYCARGAR GTNTGYTCNTCNATGGTNGARGARAAYAARYTNATHGARACNATHGARAARYTNATGGGN GGNGAYAARCARACNGARATGCARATGTCNGCNGCNGARYTNYTNACNAAYYTNCAYMGN TGYGGNGCNATHCCNGCNACNGAYTTYATHATHAGYMGNAARACNYTNGGNACNYTNGTN MGNATGTGYYTNCAYGAYMGNTCNATHCCNGARAAYATHMGNGGNGCNGARATHYTNGCN TAYYTNGTNGARATHGAYTCNGARYTNCARGTNATGGCNAGYTAYACNCAYCAYYTNATH AGYACNYTNTCNTAYTGYYTNGAYGARAARAAYCARTCNAAYMGNYTNCCNGTNTCNGAY CARGAYGTNGAYTGGTCNAGYGARATGMGNMGNGCNGCNTTYYTNGCNTTYGCNTCNATH AGYGCNAAYGAYGARGARATHMGNGARAARGTNATHAARCARAARGAYYTNATHATHAAY YTNCARAARTCNGTNTCNAGYACNAAYGARGAYGARGTNGCNGCNGGNYTNMGNTGYYTN CARTCNYTNACNMGNTCNGTNCARCARATHMGNACNGTNYTNCAYGAYAAYGCNGTNTGG MGNCCNYTNYTNCARACNATHCARTCNYTNTAYAARAARYTN---AAYMGNGARATHATG GTNYTNTCNATGGCNTGYYTNTGYAAYYTNGTNYTNGARTTYTCNCCNAGYAARGARGCN YTNGTNGARAAYAAYGCNATHAAYATHTTYTGYGAYATGTGYMGNAGYGARGAYAAYATH GTNMGNYTNAAYGCNACNTGGGGNATHATGTCNATGTCNTAYTGYGCNACNGARGAYYTN MGNATGAAYATHATHCAYACNYTNGGNACNGARACNYTNGTNAARTGYATHCARGAYCCN YTNYTNYTNATHMGNGARAARGCNYTNTCNATHGTNMGNAAYYTNYTNACNGAYAARACN TCNATHGAYAAYACNATGAARATHYTNGGNAAYGARGTNATGGARGCNGTNTTYGGNATH YTNATGGAYCCNGAYATGCCNACNAAYGTNGTNTCNCARGCNYTNTGYGCNATHAGYAAY ATGGCNGAYGGNCCNTCNTGYAARAAYTAYATHATHCCNAARACNGAYGARATHAAYGCN GTNGTNAARTAYYTNCARTAYCCNGAYAARAAYYTNCARYTNCCNGCNATHCARTTYGTN AGYAAYYTNGTNGAYCCNAGYGAYGAYGGN------------------GCNAAYTCNTGY CARMGNATGTAYCARYTNAARACNYTNGGNGTNCARTCNYTNYTNGARGCNYTNYTNGGN ACNGGNGTNGAYGARGTNGARYTNCARGCNCARCARGCNYTNAARTAYTTY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARCARAARYTNAARACNGAYACNTCNCCNCAR------MGNCCNGCNCCN ACNAAYAAYCCNTTYTCNAGYCCNAAY---TCNTCNTCNGCNCARCARCCNGAYYTNTTY GGNTCNCCNGTN---------AAYGGNTCNAGYAARGCNAGYGAYGAYYTNYTNAGYYTN AGYGCNAAYCCNTTYGCNGAYAAYGTNACN---------------------AAYGCNTAY CCNGCNGCNCCNACNTCNAAYCCNTTYGGNGCNCCNGCNTTYCARACNAAYGGNTAYTCN ACNGCN---------------TTYGAYGCNGAYTTYGCNAGYGCNTTYAAYAAYTCNGGN GCNAAYTCNCARCCNACNTCNAGYATHGCNGTNCCNACNTCNACNGCNCARCCNGTNAGY TTYGAYGCNTTYGGNGARGTNATGACNCCNATGAAYAARTCNCCNACNCAYCARGCNCAR GGNAAYCARGCNGGNMGNGCNYTNGGNGGNGAYYTNGAYTCNTCNYTNGCNTCNYTNGCN TCNAAYYTNTCNGTNAGYGGNGGNACNGGNCARYTNAARAARGAYCAYCARTGGCAYCCN AARGGNGARAGYAARYTNACNGGNGGNCARTCNTTYCARMGNCCNCCNATHGCNACNTCN ACNACNCCNGCNGCNCCNCARTGGGGNCARCARCCNGGNTTYCARCARCCN--------- ATGATGGGNGCNGGNGGNGCNCCNATGATGTAYGGNCARCARATGGGNATGCCNATGGGN CARCCNATGATGCARCCNATGGGNATGATGGGNATGGCNCARCARCCNATG--------- ---ATGTAYGGNGCNCCNCCNMGNATGGCNGGNAAYCCNGCNGCNTTYGGNCARCCNCAR ACNCARATGGCNCARCARCCNCCNCARTCNAAYATHAAYGAYCCNTTYGGNGCNYTNGAR TCNMGNAARMGNYTNMGNCCNYTNYTNMGNAARGTNAARGCNMGNGARTTYGGNYTNMGN TGGATHGAYGARMGNAAYGGNATHTTYAGYATHCCNTGGATHCAYAARAGYAAYMGNTCN TGGGAYGGNTCNTAYTGYGARATHTTYAARGARTGGGCNAARTTYACNAAYAARCAYAAR GARGGNGARGCNGARGAYTGGCCNGGNTGGAARACNMGNYTNMGNACNGCNYTNACNAAR YTNAAYGAYTTYGARGARYTNAARGAYCARCAYCARYTNGARATHGAYMGNCCNTAYMGN GTNTAYMGNTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GAYGTNTCNTCN TTYGARCCNATHGTNGAYGTNAAYGAYTTYACNAAYACNMGNAGY---------GGNAAR GGNMGNGGNGGNCARTTYCAR---------CAY------------------GAYAARGAY GGNCCNTCNCAYACNCCNAARAAYMGNMGNMGNTCNCARCAYAARGARGARGCNGGNTAY TCNCAYCAYTCNACNATHGAYMGNGTNGCNGTNGCNTTYGAYTAYGARCCNATHGTNGAY YTNAGYGAYYTNGAYCAYMGNTTYGGN---------------CCNMGNCCNTCNGCNGTN AAYAGYGGNGGNAAYCAYMGNGGNTAYAAYGCNGGNAAYGCNMGNTAYAAYMGNMGNAGY GAYCCNCCNGARAAYMGNAAYCARCCNTCN------------------MGNTAYGAYGGN MGNYTNCARGGNGAYAAYAAYCCNCCNCCNGAYCCNACNTTYAAYCCNYTNTCNGAYTGG MGNMGNGGNGGNGGNTCNGAYAAYMGNAARGARGGNTTYGARMGNCARGAYMGNTCNGAY CAYAARMGNCAYCCNMGNAAYTAYGGNGGNGGNTCNGAYYTNTCNMGNGTNAARGAYAAY ATHAARAAYATGMGNGARAARGARMGNGAYMGNCCNGGNGGNAAYAARCCNYTNGARYTN GTNATGACNGGNMGNGARMGNAARAAYCAYGARCAYTGGAARCARGARMGNGAYMGNTTY GAYAAYGARMGNGTNCARMGNCARATGATHGAYGGNGGNGGNTGGAARMGNGARTGGGAY CARGAYAARGTNGTNYTNGAYTAYGAYGARACNTCNTAY------GGNMGNACNGARCCN GCNAARMGNCCN------------------------------------------------ ------------------------------GCNGGNMGNATHGGNAGYGGNMGNTTYGAY MGNGGNGAYAGYMGNGARGAYMGNCCNAARGCNCCNACNMGNGARGGNAARGGNGCNCAR CARTAYAAYTCNTCNCCNCARCARAAYAAYACNAAYATHCAYCAYCARCARTCNCCNACN AGYCCNCARCAYGCNACNYTNATGCARCCNAARGGNMGNGGNMGNGGNMGNGGNMGNGGN MGNGGNTCNGCNGCNGTNCARGTNGGNAGYAGYAGYCCNGGNGAYAARTCNCCNMGNCCN MGNACNTGGTCNGGNGGNGAYGAYMGNTTYGTNGARTGYCARAARGARATGYTNGTNGTN AARTTYGAYAAYACNATHGGNGAYGAYTCNGTNGARGTNGARTAYGARAAYGGNGCNCCN YTNTCNCCNACNCCNTCNTCNAARTCNTCNGGNTCNACNCCNGGNMGNGGNCCNACNGGN MGNACNCCNAAYCARGGNGGNTCNAAYMGNAAYAARGGNGGNMGNCARAAYAAYCCNAAR TCNGAYMGNACNCCNGCNGAYCAYCARYTNGGNAAYAARCARTCNCCNAARAAYTAYCCN GAYCARTTYGTNGAYGCNGAYGTNTCNAAYATGATHAAYCAYCAYMGNCAYTCNTAYCCN GARGGNGGNTCNAARATHMGNACNTAYTCNTCNCAYTCNCARAGYCARGGNGAYAGYGAR GARTGGGARGAYTGYACNCARTCNTCNGGNGCNCCNGARGAYGAYCAYCAY--------- ---------AAYCCNCARYTNCAYATHGAYTGYCARYTNAAYCCNGAYGCNCCNGARTTY YTNCCNACNTCNCCNGARTTYYTNAARACNCCNCCNGGNCAYGTNAARGTNYTNAAYTGG GCNGGNAGY---CARACNCCNACNTCNCCNYTNTCNCARCCNAGYYTNACNTCNCCN--- ---------------------------TCNCCNTCNCCNMGNCARCARTCNCARCCNGAY GARGGNTCNATHCAYTCNTCNGTNTCNTCNCCNGGNTCNTCNGCNTCNACNMGNGCNAAR AAYMGNMGNGAYGARATGGAYATGATGCCNGARCCNGAYGARCCNATGCCNCCNCCNTTY YTNYTNGARATG------------------AAYGGNGCNGTNAARAAYGARTCNAARGCN GAYGARAAYGGNGTNACNAAYGAYGCNGAYGCNGARATHGARGAYGAYGAYGAYGAYGAY AARTTYGTN------GAYTCNGTNGAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNGTNGAYAAYTGYCCN CARAAYGTNMGNAAYGAYMGNYTNAARYTNTTYGAYGARAARTGYTAYTCNTTYGARACN GAYAARAARGTNTCNTTYGAYGARGCNGARGCNTTYTGYGARMGNAAYGAYGGNACNYTN GCNATHATHAARTCNYTNACNGTNAAYGARTTYATHCAYAGYGARYTNGARCARYTNACN TCNTCNTCNGCNTGGATHGGNATGYTNTAYAGYAARACNGAYGGNGGNTAYMGNTGGATH GAYGGNTCNGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AGYYTNTCNYTNGGNYTNAAYATGGGNACN MGNCCNTAYAAYGCNGCNCCNGGNGCNGARGCNGCNAARTTYMGNAAYCCNGGNYTNGTN TCNCCNGGNAAYGGNATHTTYAGYAAYGCNATGTTYCARAAYMGNTCNGTNACNCCNMGN AGYTCNAGYATGACNAARGARGTNTCNMGNAGYMGNYTNYTNGARGAYTTYMGNAAYAAY MGNATHCCNAGYYTNTCNYTNAARGAYYTNGTNAAYCAYGTNGTNGARTTYTCNCARGAY CARCAYGGNTCNMGNTTYATHCARCARAARYTNGARMGNGCNACNCCNCARGARAARGGN ATGGTNTTYGCNGARATHATHTCNGCNGCNTAYTCNYTNATGACNGAYGTNTTYGGNAAY TAYGTNATHCARAARTTYTTYGARTTYGGNTCNCCNGAYCARAARCARACNYTNGCNCAR MGNGTNMGNGGNCAYGTNYTNCCNYTNGCNYTNCARATGTAYGGNTGYMGNGTNATHCAR AARGCNYTNGARTCNATHCCNTCNGARATGCARGTNGARATHGTNAARGARYTNGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------MGNTTYGGNAGYAGYAAYGAYMGNGARAAYMGNGGNTTYAAYMGN CCNMGNMGNTTYGARAARATHAAYAAYTCNCARCCNATGGAYGGN------CCNGARATH GAYACNTGGACNAAYGARACNGCNGARATHACN---ACNAAYAARGAYACNGAYTGGAAY AGYTGGAAYGARTCNTGGGTNAAYGAYGARGAYCARTGGACNGGNACNYTNGARGARACN AARGTNTTYACNCCNTCNCAYGTNAARATGCCNGARCCNGAYCCNGTNAAYAAYGARCCN CCNAGYTCNYTNGGNCARMGNYTNGAYGTNGGNAGYYTNTTYGARAGYGCNAARTTYTCN AARGCNCCNGAYTAYAGYAARCCNACNGGNGAYTCNTAYATHACNCARTTYAAYCARGCN GCNACNGARTCNATHAARAAYTCNATHGGNATHGGNTCNGCNCCNMGN------------ ---CARCARATGGGNATGACNCCNCARAAYTCNTCNACNTCNYTNGGNYTNTCNAAYYTN GGNCARAAYACNGCNCARGTNCAR---AAYTCNGTNYTNTCNTCNYTNCARCARACNAGY TCNCARAGYGTNATHGCNCAYGCNCAYGGNATGACNCCNYTNTCNCARATGTCNCARCCN GGNTCN---AAYCCNAGYYTNTCNCARATHGGNATGGGNAAYCCNTCNGTNCARGTNAGY AGYAGYCCNGCNCCNCAR------------------------------------------ ---------------CARTCNMGNATHCCNTCNGTNGTNCARCARCARCARATGCCNCAR CCNACNATG------------------------AAYAGYATGCARCAYMGNTCNAARCCN CARMGNTCNAARYTNCCNCCNCCNTCNAARATHCCNGCNACNGCNGTNGARATGCCNGGN CAYATHCCNMGNAAYCCNCARYTNGAYGTNCARTTYGGNYTNGAYTTYGGNCCNGARCCN ACNGTNCARTTYGGNTTYGGNGGNAGYGGNGAYAGYCCNGCNGTNACNACNCCNTAY--- ACNACNTCNAAYGGN---CCNGAYGTNATHTCNAAYCAYYTNAAYCARAGYCAYGTNACN CARTCNGCNGGNGAYGGNAAY------TCNTCNATHATGCCNCCNCCNCCNGCNAAYTCN AAYAARGTNCCNCCNGGNATGGARCCNCARGCNCCNAAYMGN---TCNGGNGTNTTYCAY AAYTCNGTNTAYTCNGCNCCNCCNCCNAAYTCNGARAGYCARCCNAAYGAYYTNGAYCAR AAYAARGTNACNGARACNATHCCNTTYYTNCCNGCNCARYTNGARMGNAARTCNAGYCCN ---ATGTCNGTNCARMGNCARGGNCARACNAAYCARAAYYTNAAYTCNGGNTCNATHACN CCNAAYAARAGYGAR---GCNACNAAYGTNGCNGCNAAYAAYTAYTCNTCNGCNAAYGGN TAYTCNGTNTCNTCNTAYCARAGYCAYCCNAARAAYTCN---------ATGTCNCAYCCN CCNATHACNCARCCNTCNCARACNTCNTCNTTYCCNGGNCARTAYCARGTNAAYCARTCN TAYCCNCCN------CCNCARACNCARTAYCCNGCNCCNCCNAAYGCNGCNCCNTTY--- CCNACNGCNCARCCNTCNCARTAY---------AAYTCNAAYGCNTCNCARAAYCARTTY CCNCCNGGNCARAAYCARTAYTCNGTNGGNACNTCNACN---------YTNTCNCAYCAR ACNCARTAYCCNTCNAGYGGNCARAAYAGYTAYGGNAAY---GGNCCNTCNCARTAYGCN GCNTAYCARAAYAAYCCNTCNTTYCCNCCNCAYCCNCARTCNCARTCNAAYTTYCCNTCN AAYCARAAYGGNACNACNGGNGCNAAYYTNTAYCCNACNTCNACNCCNTCNAGYGTNCCN ACNTAYTCNTCNCARTCNAAYTCNTAYCARTCNCCNTCNGCNGGNTCNTAYCAYACNTCN MGNGARGTNTCNACNAGYATHCCNGTNAGYACNCARTCNGGNTCNGGNATGCCNTTYCCN AAYCARCCNCCNGCNTCNAGYYTNAARCCNGCNTCNTCNCARAAYTCNTCNAAYTTYAAY CARCARAAYTAYAAYGCNCCNCCNGCNCCNYTNCARCCNTCNTCNYTNGCNAAYAARYTN GGNGARAGYYTNTCNAARATGACNYTNAARGAY---CARGCNGTNYTNGAYAAYCAYCCN TCNACNCARCARCARTAYACNGTNTCN---TCNATHGTNCCNACNACNGTNAGYYTNCCN CCNGCNTCNTCNTCNGCNTCNYTNTCNACNGGNACNAAYACNATHYTNTCNACNTCNACN ACNACNTCNGCNTCNTCNAGYTCNMGNGTNACNTCNATGCCNTCNACNTCNGGNAARGCN CCNCCNAAYYTNCCNCCNGGNGTNCCNYTNGTNGGNCARTAYATHATGGGNCARAAYACN ATHCCNCCNTTYTAYAGYGTNCARCCNCCNYTNTAYGGNTAYGARGAYATGCARYTNYTN CARCARMGNATGCCNATGCARACNGGNGGNTTYTAYGAYGTNAGYGCNTTYCCN---GCN CCNGCNGGNTCNACNYTNCCNACNGGNMGNGAYCARCARCCNTCNATHCARAGYGTNCCN TTYTCNGGNCCNTCNACNGCNAARYTNACNMGNGTNGAYGCNCARAGYCCNAAYGCNTCN AGYCARCCNCARAAYGCNCAYTCNGCNCARCARCCN---YTNTTYAAYTTYCAYTAYGGN TAYTAYTAYCCNTCNATGTTYCCNGGNGCNGCNGGNYTNCARTAYCCNACNACNGTNTAY CCNATHCCNCCNGTNACNAAYACNGCNGCNCAYCCNGGNACNACNTCNAGYACNCARTTY CARAARTCNTAYCCNTCNCAYGTNTAYACNACNAARGGNTAYGAYGARATGAAYCARGTN CCNGAYTTYTCNAARACNGGNTAYGGNAGYTCNCARACNGCNGGNAARGCNGCNGGNACN MGNATGTCNACNMGNTCNGGNACNAAYGARATHGCNCCNAAYGCNTAYAGYAARTCNCAY CARCAR---GGNTTYGAYAARCARGGNTAYCAYGGNGGNACNCCNCCNCCNTTYAAYYTN CCNATGGCNTCNGCNGCNCARACNGGNCCNATGGGNGCNCCNACNACNCCNTAYGGNGCN CCNTTYYTNCCNGTNATGGCNGCNCAYCARCCNCAYTCNCARATGATGCAYCAYCCNATG CARCARGAYTCNAGYAAYAGYAGYTCNMGNGGNATGAAYCCNGCNGGNGGNCCNGTNAAR TCNGGNGCNGCNAARCCNTTYGGNGGN---CCNCCNTAYTGGAAYAAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GGNAGY TGYCCNYTNTAYGTNGAYAARCAYGGN---------GCNGCNGGNTCNGAYGCNAAYTGY GGNTAYCCNATGGCNATGGCNATHATGTTYCARYTNATGTAYYTNYTNTTYMGNATGGTN ACNYTNGTNYTNGTNATGYTNGGNAARTTYACNCCNGAYATGGTNYTNTTYTCNGAYYTN GCNGARYTNATHTAYGTNATHGCNGAYYTNGTNGCNGGNTTYYTNATHTTYATHGCNGCN TGYATHYTNTCNGCNGGNACNAAYGTNACNTGYGAYTCNTAYGCNTGYGAYCAYACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TTYAARTAYMGNATHCARMGNMGNATGTAYCAYGGNTGY--------------------- AGYGARAARGCN---ATHTCNACNGCNTCNYTNCCNYTNACNGARGTNTCNATGGARTAY TTYCARGAYAGYTTYGAYGGNTCNGARGGNYTNGGNMGNYTNGAYATGCCNATGACNACN ACNATHACNAARAARAAYAARGTNTCNCCNTGYTCNGTNGTNYTNTCNATGYTNTAYGCN AARMGNYTNMGNCARAGYAAYMGNGARTAYYTNCARTCNATGTCNTCNACNGAYGTNTTY TTYATHTCNATGATGATGGCNAGYAARTAYYTNTAYGAYGARGGNGTNGAYGARGARGTN TAYAAYGAYGARTGGGCNGAYAGYGTNGGNCARGAYGTNGAYGAYGTNAAYCARATGGAR ATGGAYTTYYTNMGNGARATGGAYTGGAARYTNTTYGTNAARCCNGARGARTTYGAYTCN GCNYTNACNGCNGTNGARMGNMGNYTNGCNYTNAARGARGGNATGAAYMGNGGNTGGTTY ACNTAYACNGARATGGCNGGNYTNYTNGAYTGGGAYCCNGTNTAYCARATGTGGAGYCAR YTNAGYCAYGAYTTYACNAARGTNGTNTCNGTNATGTCNGCNGTNTAYGTNGCNAGYYTN YTNAGYATGATGGGNTCNGCNGCNATHGCNYTNCARYTNTGYGGNCCNATGGCNTCNGCN ACNATHTCNATHYTNACN------------------------------------------ ---AARTGYTGYACNGCNAARCAYAARTAYCARTGYACNTCNACNCARATHMGNYTNCCN TGYTTYTAYMGNGTNAARTAYAAYAARTGGGARTGGTGYTGYCCNGTNTGGCCNMGN--- ---GTNYTNTTYGCNMGNTGYGAYTGYTGYAAYTGYGCNGTNYTNACNAGYGCNTGYGCN TAYACNGGNAARTGYCARMGNMGNTAYTCNAARCARAGYTTYGTNGCNGTNTGY---TAY MGNAAYTCNGCNTGGGCNACNYTNMGNTAYATHTCNAARTGGYTNCCNTCNAGYTGYTAY TGYMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGTNTGYGTN CCNTGYTTYYTNATHCCNGTNATHYTNTGGATHTTYCAYAARTTYATHCARCCNTGGYTN TCNAARTTYTGGAGYGGNTCNGARAAYTAYGTNACNAGYAAYYTNACNTGYCCNYTNCCN CARAARAARAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGAGYAAYTAYAAYCAR YTNGAYACNMGNAAYCCNGAYGGNAARGARATGCARATHYTNYTNACNGGNTTYYTNAAY AGYAARAAYGCNMGNYTNTTYGTNGCNGARYTNTGGAARCAYYTNGCNAGYGCNCARGAR AAYATHACNGGNATHCCNTCNGARTTYATHGARCARAARAARAAYGARATHAARCARMGN CARGARGARCARGARMGNYTNCARGARGARYTNAARMGNAAYGARGARYTNATHAARGAR CARYTNTCNMGNGARMGNAARGARACNGARAAR--------------------------- ---AARGAYYTNGAYAAYYTNTCNCCNGAYMGNAARGAYGCNGAYGAYGTNAARCCNYTN GCNGARAGYGGNGAYGGNYTNGAYGARAARAARGARGAY---------GTNAARTCNGAR GCNAAYGGNGARTCNAARGCNAARGARAAYCAYGARAGYGAYGARGARAARAARGARTCN AARGAYAAR---------GAYAARGAYAARTCNCCNGAYMGNAARMGNGARMGNGAY--- ------------AARGAYMGNMGNMGNCAYTCNMGNTCNCCNGAYMGNCAYMGNMGN--- MGNTCNMGNACNCCNGAYMGN---MGNGAYMGNGGNGAYAARGAYMGNTCNMGNCCNGAY CAYGGNMGNCAYTCNCCNGTN------MGNMGNMGNTCNMGNTCNCCNMGNMGNMGNTCN TCNCCNMGNMGNMGNTCNCCNAGYCCNMGNCCNGCNTCNCCN------------------ ------------------------------------------------CAYAARMGNAAR TCNCCNAARAARGCNGCNCCNCCNAARMGNAGYMGNTCNAGYAGYTCNAGYAGYTCNAGY GGNTCNGARGAYGAR------------------GAYGGNTCNCCNGAYAARGCNGGNGTN CARCARMGNMGNAAYTAYMGNAARCAYGAYGARAAYAGYGGNAARGARTCNTCNTCNGAY TCNTCNGGNGAY------------------------------------------------ GARMGN------------AARAARMGNMGNGGNCCNCCNCCNMGNGAYMGNMGN------ ---TAYMGNAGYCCNTCNCCNMGNMGNCCNCCNCCNCCN--------------------- ------MGNMGNCCNAGYCCNMGNMGNMGNMGNMGNTAYCCNTCNCCNMGNMGNATGAGY CCNCCNCAYTTYAGYYTNTCNCCNMGNMGNCCNCCNCCNCCNCCNMGNMGNMGNAGYCCN CCNCCNCCNCCNMGNMGNMGNATGTCNATHTCNCCNMGNMGNMGNMGNTCNTCNCCNCCN MGNMGNCCNMGNMGNMGNMGNCCNTCNMGNTCNCCNTCNAAYTCNCCNGTNAARMGNMGN MGNCCNCCNMGNGAYGCNTCNCCNCCNGCNAARGCNMGNAARMGNAARGAYACNCARACN GCNTCNGARTCNGGNTCNGAY------TCNAGYTCNGGNGARTCNTCNCCNTCNCCNCCN CCNGTNAARMGN---------AARAGYAARGAR------------------------GCN CCNCCNCCNAARMGNAARCCNCCNTCNCCNAARCCNGTNCARTCNGGNAGYGARAGYTCN TCNTCNGGNTCN---------GAYGARAGYGARGARGAYTCNGAYTCNGARGARCARTCN CCNAAYAARCARTGGAARGARGCNAGYCCNCCNMGNATHGTNAARTCNCCNMGNCARGCN TCNAAYGAYAAYMGNTCNMGNTCNMGNTCNCCNAARAAYMGNMGNGAYAAYMGNCCNCCN ---------------------MGNMGNTCNMGNTCNCCNGTNAARCARMGNMGNACNGCN TCNCCNCCNCCNCCNCCNMGNMGNMGNGGNGGNTCNTCNMGNTCNCCNCCNCCN------ ------------CCNMGNMGNCARCARMGNAAYACNGAYACNTCN---GAYCAYGARCCN GTNMGNMGNGAYMGNAAYCCNMGNGAYAAYTCNAGYCCNCCNMGNAARMGNMGN------ ---CCNMGNTCNCCNTCNCCNMGN------------MGNGAYAGYGGNMGNCCNGCNCAR GCNMGNTCNCCNCCNCCNMGNGARAARMGNMGNGARATGGAYGGNGCNGGNMGN------ ---------------AARGGNAARMGNCCNCCNTCNTCNGARAGYAGYAGYGGNAGYAGY TCNGAR---------------GARGARGARGTNGTNAARCARAAYAARMGNGGNTCNGGN ---------------------------------------GGNCCNCCNCCNMGNAAR--- ------------------MGNTCNGTNAGYCCNCCNTCNMGNCCNCCNCCN--------- ------------------------------------------------------------ ---------------------------------------------------------AAR TCNTCNMGNAARGARGAYCAYTCNCCNACNMGNAAYGGNAAR------------------ ------------------------------------------------------------ GTNTCNGAYGTNAARGGNAARAARGARMGNCCNGTNCARTCNAGYAGYAGYGAYTCNGAR GAY---TCNGAYTCNGAY---GCNTCNAARAARAARAARAARAARAARGARAARAARCAY AARAARCAYAARAARCAYAARAARCAYAARCAYAARAAR---------GARACNCARGAR AARGGNGARGAYYTNGARCARMGNYTNMGNGARAARGCNYTNATGTCNYTN------AAY MGNAAR---AARGARGAYAGYCCNGAYAARGAYGAYTCNGGNAGYGGNAGYAGYAGYGGN GARGARTCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARYTNGCNATGTTYGAYYTNAGYCARYTNAARTAYAAR GARMGNGAYTTYYTNGARGGNATHTTYAARTTYTGGMGNGAYAARGARAARGTNAARATG CCNTTYGARATHACNAARTGYTGGGAYYTNMGNYTNMGNCARYTNYTNGGNGTNMGNTAY GAYAGYMGNCCNAAYGCNTTYGAYTGGGAYTAYAAYATGGARATGYTNGARMGNGGNGGN TCNATHATHCAYYTNMGNCARTAYAARTCNTGGMGNGARGAYGGNATHGCNTAYACNATH MGNGARGGNACNTAYGAYATHCCNAAYMGNACNYTNTCNTCNGCNATGGTNTTYAARCAY GARGGNGAYMGNTAYCCNMGNMGNGGNTTYTGGGGNGAYATGYTNGTNTCNCCNTAYGCN ACNTTYGGNATHGARACNGARGARAARTCNYTNTAYAARAARCARAAYGAYCARCAYACN AARACNGCNGARGAYGTNGCNGARTTYAAYGTNYTNTCNYTNYTNCAYGARYTNACNACN AAYTCNAARTAYCARCCNCCNGTNGTN------ACNCCNCCNCCNAARGARGAYAGYTCN GAYAGYAARACNGCNACNYTNGARGARATHATHGARGARGARGARGAYGTNAARGGNGAY AAYCCNAAYGARAAYGAYACNACNGARGAYAARCARGGNGARGARAGYGTNCCNAARCCN TCNGTNGAYAGYGARGAYTAYGARTGGACNACNYTNGAYGAYATHAARATHACNTTYYTN CCNYTNGCNTGYGTNAARGAYATHGCNAARAARAGYAARTAYCARAARATGTTYCAYGCN GCNTTYTTYTCNAAYAGYATGGCNCAYYTNYTNACNCARGARGTNACNCCNATGTTYGCN GAYACNTGYTCNGTNGTNATGGARACNGCNYTNTTYATGYTNAGYYTNAARAARCCNGAR GTNCARGARTTYGTNAARAARATHACNGGNATHGCNAARGCNGCNGGNTGYGAYTCNYTN GAYGCNATHGAYGAYYTNCARGAYTCNTAYGCNACNTTYGGNTTYCARMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TTYGTNYTNGCNTTYTCNATHGTNGGNGCNGTNCAR MGNCCNMGNGGNGTNTCNYTNGARAARGCNTCNTTYTAYCARGCNGGNAARGAYTTYMGN TGYYTNACNGAYGGNAARGTNYTNCCNTTYGAYCAYGTNAAYGAYGAYTAYTGYGAYTGY GARGAYGGNTCNGAYGARCCNGGNACNTCNGCNTGYGCNAAYGGNYTNTTYTAYTGYGAR AAYAARTCNCAYAARGGNTCNTAYATHATHACNTCNMGNGTNAAYGAYGGNATHTGYGAY TGYTGYGAYGGNGGNGAYGARTTYGAYGGNACNATHGAYTGYCCNAAYGTNTGYGTNGAR ATGCARCARAARGARCARGCNGARCARGARGTNTTYMGNMGNGCNCARACNGARGGNTAY AARGTNAARCARGARTAYATGCARCARGGNAARMGNGCNAARGAYGARAARYTNTCNAAR YTNAGYGARYTNGARMGNGARAARGARACNTAYACNAARGARAARGAYGCNGCNGARGCN GCNAARAAYGCNGCNGARGARCCNGARAARATHGCNATHGARGARCAYAARAARGCNTGG GARGCNAARAARGARGARAARAARAARGCNCARGARGCNGCNGAYGCNGCNGARGCNTTY MGNATHYTNGAYTCNAAYGAYGAYGGNAARATHGAYTAYCCNGARYTNATGAARCAYMGN GARTTYGAYATHGAYTCNGAYGGNACNGTNAGYGARGARGARGCNMGNGARTAYYTNGAR GARAAYGARGARGTNGAYGCNTCNGTNTTYAGYGARAARATHTGGCCNAAYATHAARGAR ATHTAYAARGTNGAYAARCCNGCNGARGARGCNGTNGARGARCARACNGARAAYGTNGAR GARGTNGCNGARGARGARAARGTN---------GARGGNGGNTCNCAY---GAYAAYGAR YTNGGNGARTCNGAY--------------------------------------------- ---------------GARGAYAARGARCCNCCNTAYGAYGARCARACNATGAARYTNGTN GCNGAYGCNGAYCARGCNMGNTCNAAYTTYAAYGARGCNGARAAYAARYTNAARGAYTTY GARAAYGARATHAGYGARATHAARAARTAYYTNGARATHGAYTTYGGNATHAAYCARGAR TTYGCNGCNYTNAARGAYCARTGYTTYGARTAYATHGAYMGNGARTAYAARTAYAARYTN TGYCCNTTYGARAARACNTCNCARGCNAAYAARAAYGGNGGNATGGARACNTCNYTNGGN GTNTGGGGNMGNTGGCAYGGNCCNGTNAAYGAYAARTAYGAYACNATGAARTAYGARAAY GGNCARGGNTGYTGGAAYGGNCCNAGYMGNTCNACNATHGTNACNYTNCAYTGYGGNTCN GTNAAYGARYTNACNAGYGCNTCNGARCCNAAYMGNTGYGARTAYCAYTTYGAYYTNACN ACNCCNGCNMGNTGYGAYCCNCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TCN GARTTYACNGCNTCNGAYAARGTNGCNYTNYTNATGGGNGCNGGNGAYTAYYTNAGYGAR CAYGCNYTNACNGCNCCNCCNAAYGAYGTNGCNACNATGGAYAAYATHTTYMGNYTNYTN GGNTTYAARGTNGTNTCNYTNYTNAAYYTNAGYAARAARGARATGYTNGCNGCNATHGAY AARTTYAARGAYYTNGTNGGNGAYGAYGTNTAYTGYGTNTTYTAYTTYTGYGGNCAYGGN TAYGARGCNTCNGGNCARTGYTTYYTNYTNCCNCCNGAYGCNCCNCARGGNTAYACNCAY GAYGAYTGYYTNTCNGCNGAYGCNATHYTNTTYAAYGTNYTNYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TTYCCNGCNYTNCAYGARYTNCARACNYTNACNATHAAYAARAAYMGNYTN AARGAYYTNAGYAAYYTNYTNGAYCARATHMGNCARCAYTAYCCNAAYYTNACNTTYYTN AGYYTNYTNGGNAAYCARGCNTGYCCNAAYCARYTNTCNTCNYTNGAYAARGAYGAYGAR GAYTAYCARMGNTAYMGNTAYTTYGTNYTNTAYAARYTNCARAARYTNAARTTYYTNGAY TCNTCNCARGTNACNGCNCARGARYTNGCNGARGCNMGNMGNGTNGGNCCNTAYATGCAR ATHGTNMGNCCNGTNGTNGAR--------------------------------------- ------------------------------------------TTYGAYGARMGNGARATG YTNCCNGAYGCNGGNCAYYTNGAYGAYGAYYTNTAYAARAGYCAYGARATGGARGARGAR AARGARGGNGAYGAYMGNYTNGAYGAR---ATHACNCCNACNGARAARGARAARCCNATG GARATHGAYYTNCCNCCNCCNGGNGTNGCNGAYGGNTTYGGNGAYAAYTTYATGGAY--- GAYGAYGGNTGYGARGAYAAYGAYGAYAAYTTYGGNGAYGTNGAYCARGAYTTYTTYGGN CARGAYTTYATGGGNACNGGNGGNYTNTTYGARGAYCCNTCNGTNATHCCN---AAYCAR ACNAAYAAYGARAGYACNCARCCNACNACNTCNCCNAARCAYGAYGCNCCNGTNGARAAR GARMGNGARGARGGNGARGARACNGTNAAYYTNCARGCNACNAAYGCNGGNGTNTCNGCN GTNTCNAGYGTNACNGGNGARCARACNACNYTNGTNCAYAAYGARGARGARGCNTTYGCN YTNGARCCNYTNGAYATHACNACNGTNCCNGGNACNGARMGNAARGGNAARMGNAARMGN AARYTNATHGTNGAYGARCARAARGGNATHCCNAGYGARACNATGAARYTNCARYTNGCN GAYTCNTCNGAYATHGTNACNTCNYTNGAYYTNGCNCCNCCNACNAARAARYTNATGYTN TGGAARGARACNGGNGGNGTNGARAARATHTTYGTNYTNCCNGGNMGNCCNYTNATHTCN AARACNTGYAARGGNYTNTAYTCNACNAAYYTNGTNTGYAARTCNGTNTCNGAYGAYTAY GARCCNGGNAGYAAYAARATHGAYYTNGAYATGGCNCCNGARATHGCNMGNGARAAYGAR MGNAAYTCNACNYTNCARGAYTCNMGNYTNTCNGARATGTCNACNATHGTNGARGARCCN TCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNGGNAARAAYGAYMGNMGNCAR GCNTCNTGGYTNAAYGGNTTYATGATGTAYAGYMGNGTNCAYMGNMGNAAYTTYATHMGN GCNAAYCCNGGNGTNCAYACNGCNTAYATHAGYAARYTNYTNGGNCARGCNTGGMGNCAR ATGAGYGGNGARGAYCARCAYYTNTAYMGNGARCAYGCNMGNATHTGYTCNCARGARYTN CARCARGTNYTNGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TGGTCNCCNGGNGAYGARGGNGTNGTNTTY YTNGCNTGGGAYCARGARAARAAYMGNYTNGGNYTNAARCAYTGYTGYCARMGNAARGGN GGNYTNTTYTAYYTNGAYYTNCARAARAGYTCNATHGARCARYTNTCNACNCARGGNACN ACNCCNMGNTTYCCNMGNTTYAGYCCNGAYATGTCNAARYTNATHTAYATHGARTCNCCN ACNGGNGGNCCNCAYTAYMGNTGYGCNCARYTNGTNACNATHGAYTGGGCNAGYMGNACN GARAARATHGTNGTNGAYATHGTNAARCAYGCNCCNGCNACNTCNTTYCARGGNATHTTY GCNYTNGCNATGGCNMGNAAYGTNTGGTTYGARGAYGGNGTNCAYGTNGCNTTYAAYACN GCNTGGMGNAGYCAYACNGCNGTNGTNATHATHAAYACNGARACNGGNGCNATHMGNMGN YTNTCNAARGGNAAYGAYGAR---AGYATGGCNGTNYTNCARGTNCAYAARTCNTGYATH YTNGTNTCNTGYTCNTCNTTYACNACNCCNCCNTAYYTNTCNATHGCNYTNYTNTCNGAY YTNGARAAYCCNGAYTCNGTNMGNTGGATHAAYCCNGAYAGYACNCCNGARAARYTNGAY TGGYTNTCNTCNTGGGARTTYYTNTAYCAYATHCCNGCNAARGAYMGNCCNGCNGCNGTN AAYGGNTTYGTNGAYTAYGARAGYATHYTNTGYYTNCCNCCNYTNGARAARGAYGGNTCN YTNCCNCCNYTNATHGTNTTYTCNCAYGGNGGNCCNCAYACNGCNTTYGAYACNAGYTTY AAYTTYGCNGTNAAYTTYTTYTGYYTNTGYGGNTAYGCNGTNYTNYTNGTNAAYTAYMGN GGNTCNTGGGGNTTYGGNCARGAYGGNGTNGARTCNYTNATHGGNGCNATHAGYGARYTN GAYGTNAARGAYGTNGARAGYGCNATGYTNAGYGCNATHGCNAARGGNAARGTNGAYGGN AAYMGNGTNYTNGCNTTYGGNGGNTCNCAYGGNGGNTTYYTNACNACNCAYYTNATHGGN CARTAYCCNAGYACNTTYAARGCNGCNTGYTCNMGNAAYCCNGTNATHAAYYTNGTNTCN ATGTGGTCNACNAGYGAYATHAARGAYTGGGTNTTYGTNGARGCNGGNATHCCNTAYGAR ATGACNTCNYTNGCNGAYGAYAARATHYTNCCNACNYTNTGGAARAAYTCNCCNATHTCN CAYGTNGAYCARGTN------------------------GTN------------ACNCCN ATH------------------YTNYTNATGGTNGGNYTNGARGAYAARMGNYTNATHAAY ACNATHMGNTGGTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TGG MGNYTNGCNCARTAYAAYAARTGYGTNTTYYTNGAYGCNGAYACNYTNGTNYTNCARAAY GTNGAYGAYYTNTTYGAYMGNGARGARYTNTCNGCNGCNCCNGAYGCNGGNTGGCCNGAY TGYTTYAAYTCNGGNGTNTTYGTNTTYGTNCCNTCNGARGAYACNTAYAAYAAYYTNYTN CARYTNGCNGTNTCNCAYGGNTCNTTYGAYGGNGGNGAYCARGGNYTNYTNAAYYTNTAY TTYAAYAGYTGGTCNACNGARGAYATHMGNAARCAYYTNCCNTTYACNTAYAAYGTNGTN TCNCARGCNTTYTAYAGYTAYYTNCCNGCNTTYAARCARTTYCARGAYCARATHAARATH GTNCAYTTYATHGGNGCNGTNAARCCNTGGCAYCAYCCNTTYAAYATHAAYACNMGNGAR GTNACNGCNYTNCARGAYACNGGNCAYAAYCARCARTTYYTNCARGTNTGGTGGAAYATH TTYATGGARAARGTNCAYCAYGAYYTNGAYCCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TTYGGNTAY ATGACNGGNGCNGCNCARAAYTTYATHATHTGGTTYGTNGCNTAYYTNGGNGGNACNTCN ATHAAYATHGCNATGGTNGTNGTNGTNAAYAGYTTYTCNTCNGTNTTYATHYTNMGNTTY ACNGGNATGGTNYTNAARAARYTNGGNCCNCARTGGACNATGTGYATGGTNYTNGTNGCN CAYTTYGTNMGNTAYYTNGGNACNTCNTTYATHCARTCNCCNTGGATHYTNYTNATHACN GARATHYTNCAYGGNATGGTNTAYTCNACNYTNTGGGCNGCNGCNTCNGGNTCNACNAGY YTNGTNGCNCCNCCNGGNACNCARGCNACNTGYCARAGYATHGCNGGNGCNGTNTAYTGG GAYYTNGGNMGNGGNYTNGGNAGYYTNATGACNGGNCARYTNATHCARGTNYTNGGNCCN MGNTGGACNTTYMGNACNTAYTCNGGNATHTGYGTNGTNGCNYTNYTNYTNTTYATHYTN YTNGAYMGNTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CCNAAYAGYGARAGY ATHACNCCNCCNTTYTCNGGNGGNAGYACNCCNCAYGTNCARTCNMGNGCNGCNTCNCCN ACNTGGAGYGARAGYAGYGGNAAYATGAGYACNAGYAGYGTNTCNGGNGTNTCNTGYCCN MGNAARYTNYTNCARGGNGCNTCNCCNGTNGTNCCNMGNCAYAARMGNCCNTCNCAYMGN MGNGCNGARGTNAARMGNMGNGAYAARATHAARACNTGYYTNGAYGAYATHAARGCNTGY GTNCCNAAYYTNCARGARAARGGNAARYTNAGYGARTCNACNATHYTNGTNAARGCNGCN GARTTYATGCAYCARYTNAARGAYGGNATHTCNGAYMGNGGNAGYAARGCNGCNGARYTN MGNMGNGARGTNCARAAYYTNAGYGARGARATHCAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNCAYAARTGGGARGARGAYCAYGCNGARATHACNACN ATHAARACNTAYYTNYTNACNCCNAAYTAYCAYYTNATHGTNACNGTNGAYGAYATGGCN GTNTCNMGNYTNTTYATHTTYGCNTTYGAYMGNATHTTYTTYATHAARGCNYTNAAYGAR AAYAGYCCNGARGGNACNACNAARATHYTNTGYCAYAARTGYGARGCNTCNYTNGARGGN GAYTAYYTNGGNATHAAYYTNGARAAYACNAGYACNAARGARGTNTGGYTNGARGTNCAY AARATGCCNATHGAYAAYTGGATHAARGAYYTNGAYACNATHCARCARTAYATGGAYAAR CARAARGARGGNGCNGARAARACNGARACNYTNCARCCNGARGARGTNACNACNTCNGCN GGNGAYGARGCNGARCCNGAYCARCCNACNGARGARGARACNCAYAGYGCNATHCAYAGY GTNGAYTCNATHATHGARAARGTNGGNCCNAARTTYGGNCAYCCNGCNATHGTNTTYAAR GCNAARCCNCCNCAYMGNTGYCCNYTN---GCNAAYCCNTCNTCNAGYGTNGCNTCNGCN ATGTCNAARGTNGAYCARGGNGAYGTNYTNGGNACNGGNACNAAYCAYGTNYTNTCNGCN GCNCAYYTNGARTCNMGNGAYGGNATGTTYGAYAAYCARCAYCARCAYYTNYTNGARTTY YTNCCNAARGARGARAAYGARAARTCNATHATGGTNACNTTYCAYTTYYTNAAYCCNAGY CAYATGYTNACNAGYGCNYTNGAYCAYAGYYTNCCNCARAAYAARCCNGTNTCNGTNATG YTNTGGTGGTCNGGNACNCARCAYGTNYTNCARTAYTCNYTNYTNAARACNGCN---AAR GAYATHGARTTYAARCCNGAYATHGTNTGGCCNTGYTCNAARACNATHACNTGYTCNAGY ACNAGYCCNTGYGGNTCNCAYYTNGCNATHGGNYTNGARAAYGGNAAYYTNATGYTNTGG GAYTAYCARATGGGNYTNCCNAARGCNGTNYTNACNGTNTCNGGNAAYGGNGGNGTNMGN AGYGTNMGNTTYYTNGAYCCNAGYYTNTTYCCNACNGAYACNCCNCAYTAYCCNCCNTAY CCNGTNACNTCNGCNACNTTYYTNYTNGCNGARTAYAAYGAYGGNACNCARGCNYTNTTY GAYACNTGYGAYGGNAGYCARCARATHCCNMGNATGATHGCNACNAARCCNGARTAYGAY GAYGAYAARGARACNYTNATHAARYTNATHCCNGAYYTNCCNGARYTNATGYTNTTYGTN AARAARAAYGGNTGYATGTAYATHAARAAYATHGGNAAYGGNACNACNYTNTGYGARGTN GTNGTNCCNGARCCNCAYAGYATHCARACNCCNTGGAAYCCNATHATHGCNYTNGGNAAY GGNGGNCAYACNYTNTTYATHAARGCNGARGGNAARGAYGTNAGYGARGAYGGNGARGTN AGYAAYATHTCNTGYYTNTTYAARTTYAAYYTNAARGARTAYTCNATHYTNGAYGARTAY TGGGCNMGNYTNMGNGARAARTCNGAYYTNATHGTNTTYACNACNTGYGARCARMGNYTN GARAAYYTNATGAARGARMGNYTNCARCARCARGCNATGMGNAARCCNMGNATGCARAAR CAYTGGGGNCARYTNMGNGGNGARYTNGAYATHATHCARAAYGCNMGNGARATHCCNGTN GAYTCNYTN--------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------------GARGCNMGN TCNGTNGCNATGGARYTNGARAARACNCAYMGNACNGAYCCNAGYTAYATHGARYTNGTN AARAARGARCAYGGNATHYTNGTNGTNGARAARGARATGTCNGGNMGNGTNAARTAYYTN GAYAARTCNGARMGNGAYYTNTTYGCNGCNYTNAGYATGMGNGTNMGNGARAGYCAYGAR AARGARMGNTCNMGNGCNGARMGNACNAARTAYTGGTCNATHGTNGGNTCNATHGTNGGN GCNGTNATHGGNATHACNGGNTCNACNTTYAAYAAYCAYMGNMGNYTNMGNGARATGMGN GCNATHGTNCARGARAGYGTNGARACNAGYGCNGARTAYAARGAYATHGCNGAYMGNGCN ATHGCNGGNTTYACNACNCARTCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNCCNGCNTAYGCNACNCCNCCNGCNTGYYTN CAYMGNGTNGGNYTNGARTCNAGYTCNACNGGNTCNTCNTTYCCNGCNGAYTTYACNAAR CCNGTNCCNYTNGCNGTNGTNTCNCCNGAYGGNMGNAAYCCNTGGACNAAYGGNGGNAGY CCNTGGGGNAARCCNACNACN------CCNGTNCCNTGYTCNYTNGARGAYGTNATGAGY GARCARYTNGCNTCNGARYTNGARACNAGYATHYTNAGYAARGARYTNGAYCAYCARGAR AAYTCNAARYTNAGYGARGCNGCNGCNGTNGAYACNGTNGCNGARGTNGCNAARGTNAAY ATHACNGAYGARGARYTNGCNGCNAARYTNGCNTCNGARGARGCNAARTAYGAYCCNAAY GAYGARYTNATHGCNYTNYTNYTNCARAARCARTAYGAYMGNGARCAYGAYGCNGARYTN TCNAARGTNGARCARAARTAYAAYGGNAAYAGYAARGTNGCNATHTCNTTYGARAAYTAY AARMGNAARAAYATGCARTCNGARTAYCARAAYGCNGARGAYGAYGAYGARGAYGAYGAR TAYTAYMGNGAYATHCCNGARTAYCCNTCNCARACNAARTGGGGNAGYGGNACNCCNATH ATHGGNGCNAARGGNTAYAGYGGNCARGGNAARAAYATHGTNACNAARCAYGAYAARGTN ATHTGYGGNMGNMGNAAYGCNCARMGNYTNATGCARTTYCCNCCNGAYTTYGGNTGYGGN GAYGGNGARGGNATGGAYATGCARYTNCCNAAYCARGTNTAYAAYAARYTNAARCARCAY TCNATGACNGARAGYGGNAARMGNCAYAARGTNYTNGARAARAARGAYCAYTCNACNGCN ATHAARGCNGTNGAYGARAARACNMGNATHYTNATHTAYAARATGATHAAYTCNGARTTY YTNACNTCNGTNGAYGGNGTNGTNAGYGARGGNAARGARGCNGTNGTNTTYAARGCNAAY GGNGGNAARAARGAYGARGTNGARGTNCCNAARGAYGTNATHYTNAARGTNTAYAARACN TCNATGAAYGARTTYAARACNMGNAGYAARTAYGTNGCNGGNGAYTAYMGNYTNTCNAAR GAYAARTTYAARAARTTYAAYCCNMGNAARATGATGMGNATHTGGGCNGARAARGARTAY YTNAAYYTNAAYAARYTNMGNMGNAAYGGNATHMGNTGYCCNACNGCNYTNGCNYTNAAR AARCAYGTNYTNGCNATGACNTGYGTNGGNGGNGARAARCCNGCNCCNAARYTNMGNGAR GTNACNYTNAAYACNGARGAYTGYCARGAYGCNTTYGARCARACNGTNGAYYTNATGAAR AARATGTAYCAYGAYTGYAAYATGGTNCAYTCNGAYTTYAGYGCNTAYAAYYTNYTNTGG CAYGAYAARAARGTNTGGGTNATHGAYGTNGGNCARGCNGTNGAYMGNGAYAAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNACN TAYYTNACNAGYCARTCNGTNGTNTGYYTNGGNYTNCARTCNGGNGAYGTNTAYAARATG GAYGCNCAYCARTAYCCNATHGTNYTNATHGGNTGYATHAGYAAYGTNGGNAARYTNGTN ACNGTNGAYACNAARGGNTTYATHAAYATHTGGAARTAYGAYACNGAYCAYGCNACNCAR AAYGGNTGYTAYGTNCCNGARTCNAARTAYMGNATHGAYTTYAAYAARYTNATGTAYATH CCNACNAGYGGNAGYTCNGCNAARATHATHTTYACNGAYMGNMGNMGNTCNMGNTCNACN CCNCARAARGAYATHGCNMGNGARMGNMGNGARGCNCARGCNACNYTNGAYMGNATHCAR YTNGGNCAYCCNTGGCAYGTNAGYATGGARTCNCCNGGNYTNGARACNTCNATHTAYATH CCNGTNGGNGGNTCNATGGAYTCNGCNGCNATGTTYAAYATHGTNATHMGNCAYGTNAAR ACNCARCARYTNTCNACNTAYATGACNMGNTAYTAYACNCCNGTNAARGTNGGNTGYTCN AARYTNYTNTCNGCNACNATHTCNCCNACNGGNAGYCARYTNGTNGCNGTNYTNYTNTTY CCNTCNTTYCCNCCNAARGCNCCNCAYYTNATGGTNYTNATHATHGAYYTNTCNCCNATH AAYYTNCARAARTTYMGNTAYGAYCAYTCNATHACNGARGCNCARCAYAARGARYTNGAR TCNAAYAARATGACNTCNGCNTCNGTNAGYCARGTNYTNGGNTCNACNGGNACNCARTAY YTNTTYYTNACNATGGGNMGNGARTTYTGGTGYGTNTCNATGGCNACNGGNAGYGGNGTN YTNATGATHGAYAAYCCNAGYAARCCNMGNGTNCCNMGNTTYCARGGNYTNGTNATHGAY GARAARCARTTYCCNATGTCNGCNAAYCARAARGTNGGNTTYGTNGGNAAYATGGGNTCN YTNTAYGCNGTNTTYTAYGAYGCNAGYTCNACNAAYATHMGNATGYTNMGNYTNGARGAY GCNAAYAAYCCNGARGTNTCNATGGCNGTNTGGAARGCNTTYCARCARTGGGARMGNTTY GARMGNACNCCNATHGARYTNMGNATHAAYTCNGTNGAYTGGACNYTNCCNGAYATGAAR CAYAARYTNGCNGARATGMGNAGYYTNGTNYTNAGYYTNCCNGCNTCNGARYTNGAYGTN GGNATHACNGARTAYATGGARGCNAAYYTNAARCCNTTYAGYGCNATHATHAARCARMGN TAYTCNGAYTTYATHGTNAAYGARATHGAYYTNGARGGNAAYGTNGTNCAYYTNAARACN ATHACNCAYAAYAAYAARGARGARGARGARGARGARGARGARGARGARAARGARGAYGCN TCNAGYGTNYTNGGNGAYACNGAYMGNGARGCNATHCARAARATGGTNAARGAYGARAAY AARTCNGAYACNCAYAAYATHCCNGCNCCNGAYGAYAARGCNYTNMGNACNAARATHCAY YTNGCNGTNAARAARAGYTTYTCNCARYTNGARACNGTNACNGGNGARGAYGARCARGGN AAYAARGTNATHAARATHACNTGGMGNAARGGNAARAAYMGNGAYGTNATHMGNGAYGAR TGGCCNAARTCNAARAARTCNTGYMGNTAYGTNMGNTTYGTNYTNTAYAARGARAAYAAR GAYACNATGGAYGCNATHGGNYTNATHGCNMGNAAYYTNAARGTNAARGARAGYATGTTY CARTTYGCNGGNACNAARGAYMGNMGNGCNAARACNAGYCARGARATHACNGCNCAYMGN GTNCAYCCNAARAARYTNGTNGGNYTNAAYAARGTNYTNTGGAAYATGGGNYTNGGNGAY TTYMGNTAYGTNCARCARCCNYTNCARYTNGGNCARYTNTCNGGNAAYCAYTTYACNATH GTNYTNMGNAAYGTNGARGCNGAYAARGARGTNGTNGAYYTNGCNYTNACNTCNYTNAAR GARAARGGNTTYATHAAYTAYTTYGGNATGCARMGNTTYGGNACNACNTCNATHGCNACN CAYACNGTNGGNAGYACNYTNYTNAARGGNGAYTGGCARAARGCNATHGAYYTNATHYTN GCNCCNMGNAAYGAYGTNCCNGTNAARGAYAARTTYCARMGNGTNTGGGCNGARACNAAR GAYGCNTCNGCNACNYTNAAYGTNACNCCNMGNTTYTGYGGNYTNGARMGNAAYATHYTN GARGCNYTNGTNAARAARGCNAARCCNTTYAAYGCNYTNGARAARYTNCCNMGNAAYAGY MGNYTNYTNTAYATHCAYAGYTAYCARTCNYTNGTNTGGAAYAARATGGTNTCNMGNMGN YTNTCNGAYYTNGGNCAYGGNGTNYTNGCNGGNGAYYTNGTNATG---TCNMGNACNACN CAYTGYGAYAARGAYGAYGAYACNACNAGYAARCCNGTNGTNGTNACNGAYGAYAAYATH AARGAYTAYACNYTNACNGAYGTNGTNYTNCCNYTNCCNGGNCAYGAYGTNATHTAYCCN GCNAAYCARGTNGGNGARTGGTAYMGNGARYTNATGACNAGYGAYGGNYTNGAYATHGAY AAYATGAARMGNCCNCARAARGAYTAYTCNYTNCCNGGNGCNTAYMGNCAYATHGTNATH ATHCCNAARAGYGTNTCNTGGAGYCAYCAYMGNTAYGAYGAYTAYACNCARCCNYTNACN YTNAGYGAYTTYGAYATHATHCARGGNGARAARYTNCARCCN---GARAARGAYGARGGN TCNYTNTCNGCNGTNGTNYTNGARATGTCNYTNCCNTCNTCNTGYTAYGCNACNATGGGN YTNMGNGARGTNATGMGNATHGAYACNTCNAGYMGNCAYCARACNACNYTNAAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATHTTYAAYGCNCCNAARGGNACNYTN---ATGGCNTCNGARYTNCCNYTNTTYCCNAAR GCNAAYACNATGTAYYTNCAYAGYGGNAAYATGATHAAYTGGAAYMGNYTNAARMGNAAR CCNAAYATGTCNTCNTCNGAYGARYTNTGYGARGTNATHAGYCAYACNYTNGARTCNTAY ATHAAYTCNGCNGAYAARACNGARYTNCARTAYGTNACNGARATHTAYAARATHAAYACN GARAAYGTNGARGTNATHGARGARAGYGARMGNGGNGAYATHAARATHACNGTNAARYTN TTYATHTGYGAYTCNCARCCNGCNTCNGTNGTNGCNGARTCNYTNGAYAARGTNYTNAAY GARYTNGARACNACNTTYGTNGARTCNYTNYTNYTNTCNATHTCNCCNAGYGTNTCNGAR GAYCARGARCCNGAR---CCNGTNACNYTNCCNACNATHCARAAYTAYTGGCARGCNATG GARGAYYTNGTNGCNAARGAYAARGTNYTNTTYYTNGGNATHTGYGAYATGGGNAARGAR GGNYTNGARTCNYTNTAYAAYTGGGCNCARGTNAARCCNTGYGTNAAYCARGTNAAYYTN GAYTCNTGYTGYGTNYTNCCNAARGAYYTNACNGARTAYGCNAARGCNGTNAAYATHCAR YTNYTNACNCAYAAYGAYMGNCCNGCNTTYGTNACNAARGARTCNGTNCARGAYAARATH CARTCNGTNGCNACNGARMGNGAYAGYGAYGCNTGGTCNCCNGARTGGGTNGTNMGNTAY TCNGGNYTNATHAARTGYMGNGGNATHATHAARATGAARGGNTAYATHTTYCAYGCNAAY MGNGAYAAYMGNAARMGNATHYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNATHATGACNYTNTCNAGYMGNCAYCCNCAYATHGGNCAR TAYATHGCNAAYAAYTCNCAYTTYTGYGCNGTNYTNGCNACNGGNYTNAAYGGNYTNTAY AGYTCNYTNCCNMGNMGNATHCCNATGCCNTGYGAYGAYTGGCAYACNATHYTNAARGAR GAYTGYYTNAARATHCCNGARYTNCARATGTTYYTNAAYTCNYTNCARTTYTCNAAYGCN GTNGTNCAR--------------------------------------------------- GARGGNCARGCNYTNGCNACNAAYGGNGCNTCNGAYMGNAARAARAARMGNMGNAGYMGN TGGAAYACNGAYAAYGAYGAYAARACNGTNATHCCNGGNATGCCNACNGTNYTNCCNGGN AAYYTNTCNGARACNCARCARMGNCARTAYGTNGTNCARYTNCARATHGARGARATHACN MGNAARYTNMGNACNGGNGARYTNGGNATHCCNTCNAAYCCNGARCARMGNTCNCCNTCN CCNGARCCNATHTAYAAYAAYGARGGNAARMGNYTNAAYACNMGNGARTAYMGNACNMGN AARAARYTNGARGARGARMGNCAYMGNTAYATHCARGARGCNATGAARYTNAAYACNGAR TTYAARCCNCCNAGYGAYTAYAARCCNCCNGTNATHMGNGTNAAYGAYAARGTNATGATH CCNCARGARGARCAYCCNGARATHAAYTTYGTNGGNYTNYTNATHGGNCCNMGNGGNAAY ACNYTNAARACNYTNGARAARGAYACNGGNGCNAARATHATHATHMGNGGNAARGGNTCN GTNAARGAYGGNAARATHGGNMGNAARGAYGGNCARCCNYTNCCNGGNGARGAYGARCCN YTNCAYGCNTAYGTNACNGCNAAYAAYCCNGARAAYGTNAARAARGCNGTNGARCARATH AARGARATHATHAARCARGGNATHGARGTNCCNGARGGNCARAAYGAYYTNMGNMGNCAR CARYTNMGNGARYTNGCNYTNYTNAAYGGNACNYTNMGNGARAAYGAYGGNYTNCARAAR YTNMGNCARATHGCNGARAGYCARACNATHGTNACNAAYACNATHATHTGYACNATGTGY GGNGGNGCNGGNCAYATHGCNCARGAYTGYAARGARAARMGNCCNGGNGAYACNTTYMGN ATGCARCARATGCARAAYCCNGCNGAYMGNGCNAARATGGAYAGYGARTAYATGTCNYTN ATGGCNGARYTNGGNGARGGNCCNGCNCCNTCNAARTCNGARACNTCNAAYTCNGGNCAR ---------------AAYCARCCNCAYTTYAAYMGNTCNATH---------CCNCCNCCN AAYCCNATGGCNATGAAYCARCCNTGGCARATG---CCN---CCNAAYMGNCCN------ ------------------------------CCNATGGGNAAYCAYGGNCCNCCNCCN--- ---CCNTCNAGYTCNGGNGGNCCNCCNAAY------------------------------ ------CAYAAYMGNCCNCCNATGGGNATGCARTCNGCNCCNCCNATGYTNCCNYTNATG TCNCAYGGNGGNCCNCCNCCNAAYTCNATGATGCCNTCNCARCAR--------------- GGNCARGGNCAYATGGGNAAYATGCARCARCCNCCNCCNCCNCCNCARGTNMGNCCNTGG CAYCARACN------------------------------CCNACNAGYCARCCNCARGGN ATGATGCCNCCNAAYTCNACNTCNAGYYTNGGN---------ATHCCNCCNCCNCCNTCN TCNATGATGGCNCCNCCNCCNCCNCCNACNAGYTCN---------CAR---GGN---CAR CARCAYCCNCCNTGGATGCARCCNCCNCCNCCNCARCARTCNGGNATGGGNCARCAYCCN CCNCCNCCNCCNCCNCCN------------ACNTCNACNGCNCCNTGG---------CAR CARCARCARCARCARCAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYMGNYTNACNTGYCCNGCNMGNATH TAYGTNAARAARGTNMGNCCNAAYTAYGCNGTNAAYYTNAAYATGGAYAARAARAGYATH MGNYTNGCNATGGAYACNGCNTTYCARGARYTNMGNGGNAAYYTNACNGARATHTGGGGN GARGAYMGNTAYTAYGTNCARYTNCCNACNGARGCNGCNCAYGAYTAYCAYGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GTNCAYCAYGTNGTNTTYATHAARACNCAYAARGCN GGNAGYTCNACNGTNGCNAAYATHYTNCARMGNTTYGGNATGYTNAAYAAYYTNACNTTY GTNYTNCCNGAYAARAARACNGGNTCNTTYGGNGTNAAYTAYYTNGTNAARGCNGGNGAY TAYYTNAARAARGARAARATHATHCCNYTNCARAGYTCNGAYCARGARTAYAAYATHYTN TGGAGYCAYAGYATHTAYAAYAARACNGCNTTYAAYAAYGTNATGAGYAAYAARTCNAAR TAYTTYACNATHYTNMGNGARCCNTTYCARCARTTYATHTCNTCNTTYGARTAYTAYGGN ATHAARAAYTCNYTNAARAARATHAAYGAYGCNATHCARGARATHTCNAAYCCNATHTCN GCNTTYTTYACNCAYCCNTTYTTYGCNAARTTYMGNCCNMGNGARTAYGGNTAYYTNMGN AAYAARCARTCNCARGAYYTNGGNTTYGGNAAYCARGARTTYTAYGAYTCNGAYAARYTN TTYGARTAYATHMGNCARATHGAYMGNGAYTTYAGYTTYGTNATGATHATGGARTAY--- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MGNGGNTGGAGYGAR AAYCCNYTNGTNTAYTGYGAYGGNCARGGNTGYAAYGTNGCNGTNCAYCARGCNTGYTAY GGNATHGTNCARGTNCCNACNGGNCCNTGGTTYTGYAARAARTGYGARTCNCARGARMGN ATHGCNMGNGTNAARTGYGARYTNTGYCCNCARMGNGAYGGNGCNYTNAARMGNACNAGY TCNGGNGGNTGGTGYCAYGTNGTNTGYGCNYTNTAYATHCCNGARGCNTGGTTYGCNAAY GTNCARACNATGGAYCCNATHGTNYTNGCNTCNGTNCCNCAYGARMGNTTYAAYAARACN TGYTAYATHTGYGARGARCARAARMGNGAYACNAARGCNACNGCNGGNGCNTGYATGCAR TGYAAYMGNACNGGNTGYAARCARTAYTTYCAYGTNACNTGYGCNCARTCNCARGGNYTN YTNTGYGARGTNAGYGGNAGYTAYGARAAYGTNATGTAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATGCCNGGNGGNMGNMGNATHYTNTCNMGNATHCARTCN AAYGGNCCNTAYTCNTCNACNGGNAARAAYTCNGGNGGNAGYGGNAGYCAYGGNGGNGAY GAYMGNGAYGGNAAYATHGTNCCNYTNGCNTCNATGGTNGTNYTNCCNAARCAYAGYCAR YTNCCNGAYATHCCNTCNGAYGGNAAYYTNTAYTTYGARTGYATGYTNTTYGTNTTYGGN ATHATHACNATGTGYYTNCARTAYATHAAYYTNTAYAARACNGTNTGGTGGYTNCCNCAR TCNCAYGCNCARTAYGCNYTNAAYTTYTAYYTNATHGAYTTYAAYYTNGCNGTNYTNATH TGYGTNATHYTNGTNGCNMGNTTYYTNATHTGYTTYTCNCARGARGTNTAYAGYAAYMGN ATGYTNTTYTGGCCNYTNGTNTGYYTNAARGCNYTNATGATHGGNTTYTCNYTNGTNGTN YTNGTNTAYACNGGNTAYAARGTNATHGCNGGNCAYGGNATHGTNACNAGYYTNTTYYTN TGYTAYCCNGCNGTNATHTAYYTNGTNYTNTTYGGNGTNGCNATHAARCCNYTNTAYCAR AARCAYCARGCNTGGCCNMGNCCNGCNTAYAGYATGGAYMGNCCNGCNGGNCCNATGMGN ATGAARATGAARGAYGAYGCNCCNYTNTGYCAYACNTGYACNYTNACNCCNGAYATHGTN MGNGARGARGTNGAYATHYTNAARAARGAYTTYAAYAGYMGNYTNAARCARATHYTNTTY AAYTCNYTNACNACNTCNTTYTAYGCNACNGGNGTNCCNGTNTGGTTYTCNCAR---AAY ACNYTNTAYTAYGAYTCNTGGTGGATGTGGCARCAYGTNTCNYTNACNTGGYTNAGYGCN YTNYTNATGYTNACNGCNCAYTTYYTNCCNCCNCAYTAYYTNCAYYTNYTNCAYAARAGY GCNMGNCAYYTNGGNMGNTGGCARMGNATGGARGCNMGNCAYGCNCAYGTNCCNTAYAAY GCNTGGTCNGARYTNCARGTNTGGCCNCARGGNGCNYTNGTNAARCAYGTNMGNGGNYTN TTYAARGCNGARGGNATHAAYGTNACNGCNGARCCNGGNAAYAAYYTNCAYAGYMGNTTY TTYATGYTNTTYCAYCARCCNATGMGNGTNATGAAYTGGYTNGTNTTYYTNACNTGYATH GTNATGGCNTAYCARGGNTTYMGNYTNYTNCARAGYTCNGARTGGAGYCAYATHATHTCN YTNGCNYTNYTNATGTTYTGYAAYTTYTAYACNYTNTTYAARYTNATGMGNGAYTGGTTY ATHATGGGNAARGTNTAYAARGARCAYGAYTAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CCNCCNAARCCNTCNMGN GTNCCNGARCCNGCNCCNTTYGAR------CARCARGARTAYGCNGAYTCNATGTCN--- YTNACNGCNYTNTTYGTNCAYGAYTGGTTYCAYGGNGAYATHAGYMGNAGYGARGGNGAR GCNMGNYTNACNMGNTTYGGNAARAARGGNGCNTTYYTNATHMGNGARAGYTCNAARAAR GGNGGNTCNACNTTYCCNTAYACNYTNGTNATHYTNACNAAYCARGARGTNAARAAYYTN MGNATHMGNMGNMGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARGCNGTNATGCARGTNGARGARAAYYTNGTNACNACNACNCAR MGNGCNGTNCARGCNGARACNTCNGTNACNAARYTNAARCARGARGTNAARTCNYTNCAR AGYCARGTNMGNAAYYTNTCNACNGARATHGARGTNTAYCARAGYGGNGAYAARGGNYTN TCNGAYATHMGNGARMGNACNAARTAYACNTCNGAYCARYTNAARATGGCNGCNGARYTN GCNGARAARAAYYTNAARGAYYTNYTNGTNGGNGTNGAYAARATGAARYTNYTNTCNCAR GTNYTNTCNAAYTGGGARAARATHACNGARGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TTYAAYGTNGAYAGYTTYAAYCAYCCNTGYATHCAR GAYTTYTAYGAYMGNATGYTNTTYACNYTNYTNGTNCCNCAYACNATHACNGARATHAAY YTNACNCCNGAYAARCCNAGYAARAARCARATGGCNTCNAGYCCNGARATGTTYMGNAGY GARTCNAGYMGN---------------------TCNTCNGCNMGNTCNTCNCCN---ACN GARAARGTNGAYCCNTTYMGNTGYGGNACNCCNYTNGTNTCNGARAAYMGNYTNTCNACN MGNMGNMGNYTNGAYTAYGGNGARGCNYTNMGNAARCAYAAYTCNMGNCCNAARACNGCN TCNGARTAYATGGCNGTNYTNGARMGNGARMGNATHAARMGNACNTCNTCNTCNACNGCN MGNGTNCARTCNGCNCARAAYAAYAAYAAYMGNTCNTCNYTNTCNTCNAARCAYGCNTCN TCNGCNAGYCARAAYTCNTCNACNCARGGNMGNGCNACNAARACNAARAGYACNAGYTGY TTYGTNTTYGARACNCCNACNAAYTAYGCNATHCCNGTNTTYCARCCNATHAAYATHGCN GARGCNCCNMGNATGTAYTAYMGNCCNTGGMGNGGNGAYAARYTNCCNATHGCNGARGTN CCNCAYCCNAARCCNTCNCCNGCNTTYTAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TCNGGNTAYMGNTAYACN GARAAYAARYTNGTNCAYACNGGNATGGCNGCNYTNACN---GARAAYAGYCARACNAAR ACNTAYYTNTTYGARGGNYTNGTNGGNAARGAYMGNTCNMGNGTNTGGGAYCAYATGCAR TTYTGGGARGAYATGTTYYTNGAYGCNGTNGCNCARGARMGNGAYATHATHGGNATGGAY CARAGYCCNTCNGAYATGATGGARMGNTAYCAYTCNYTNMGNGARYTNGARMGNAARMGN YTNGARTTYGAYGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGGGNCARTAYACNTCNMGN CARGAYATHATHCAYAARGARGTNAGYGAYYTNAARATGMGNAAYTGGYTNTGYGCNAAY YTNGCNATGMGNGARTCNTCNAARGAYATHGCNATHTGYGTNCAYAARAARATHTCNCAR ATHCAYAARGARATGYTNCARGCNGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNYTNTCNGAYTGGGAYATHGARTGYATHGCNATHGGNTCNGGNATHTAYGGNTGY GGNGGNGGNGGNAAYGTNCAYATHGGNMGNATHMGNGCNYTNMGNGCNATHMGNGCNGGN AARAARATHACNGTNCARMGNCCNGARAARATHATGGCNAAYGCNGAYCCNMGNAARGAY YTNGTNTTYTGYGTNGGNGCNATHGGNTCNCCNACNGTNGCNTAYGARTCNGGNGTNGCN ACNGTNGARCCNMGNGTNGCNATHCARTGYYTNAARGAYGTNTAYGARYTNGGNCARTAY GCNAAYGGNAAYYTNCARAAYYTNAAYAAYGTNAARGTNGARGARAAYGARAAYGGNGAY MGNTTYATHACNAAYTAYCARCCNATHMGNGARAARAAYGTNGAYGARTAYAARGTNATH GGNYTNATGTCNTTYGARTTYGCNGGNYTNAAYGCNATGGARCCNYTNGTNYTNTCNGCN GARYTNGGNATHCCNYTNYTNGAYGCNGAYTGYATGACNMGNGCNTTYCCNTGYGTNGAY ATGTTYATHCCNTTYATHTAYGGNAARCARCCNCAYCCNTTYTCNATHGTNGGNGTNGGN TCNATHACNGARMGNAGYGTNYTNYTNCARACNCCNTTYCCNAARCARGCNGARGAYTAY YTNMGNGCNGTNTGYATHAARCAYGGNTGYTTYGGNCAYYTNTCNYTNGCNYTNGAYAAR ACNGAYGTNATGTCNMGNACNGTNCAYAAYGTNGTNAGYAGYGCNTGGGCNYTNGGNGAY GCNATHYTNMGNGCNMGNATHAAYAARACNTCNGTNATHGAYGCNATHGTNGARCARGAR AAYGGNAARACNATHGTNATGGGNAARGTNGTNGAYGTNMGNMGNGARACNATHGAYGGN YTNAAYAARGGNTTYGTNAGYATHGARGGNATHGAYGARTGGGTNAARCARAAYATHACN ATHGAYTTYCARAAYGARTTYYTNGTNGTNTTY------------GAYCCNGARGGNAAY CCNGTNGGNTGYGTNCCNGAYATGATHGCNGTNGTNGAYYTNGAYACNGGNGARCCNATH ACNGCNGARGARYTNMGNTAYGGNATGATGGTNGCNGTNYTNYTNATGCCNTCNTGYGAY ATGYTNMGNACNGARAARGCNYTNGCNGTNGTNGGNCCNCARGCNTTYMGNTAYGAYGAY AARGTNGTNTTYAARCCNTTYMGNGARMGNAARGCNGAYCARCCNATH------------ ------------------------------------CCNCCNMGNAGYYTNGGNAGYACN GCNTCNGAYAGYTCNGAYACNTTYCCNGCNTCNTCNACNAGYAGYTCNGAYATHCCNGAY GGNCARMGNGTNTCNAAYGGNTCNTCNTCNTCNACNCCNTCNCCNTCNACNGARGTNAGY TGYCARYTNGCNAARYTNAARTCNGAYYTNTCNGTNYTNMGNMGNCARACNCARYTNAAY ATGGARTCNATGMGNGARGARTTYATGAARGCNAAYAAYACNATHAARAARGTNATHTCN TCNGTNCCNGGNGCNGAYAAYCARATHAGYTTYCAYAGYMGNATHGARGCNACNAARAAR AARACNTCNTAYATHAGYGARAARTTYCARGTNGAYCARGARYTNAGYGAYYTNGARTTY AGYGTNGARGARYTNMGNAAYGAYATHATHAAYCAYCARTGYMGNGTNCARYTNGCNGAY GTNGARGCNATGGCNYTNYTNYTNAGYAAYATHACNAARAAYYTNGCNGAYYTNAARACN CARTTYCCNGAYGTNAAYGARGTNATGAARCARGTNATGAAYAAYGARATGCARATHGTN GTNGCNGARGARAAYTTYYTNAARGARGARCCNTCNAARATHGARAARTCNYTNATGMGN TGYAARAARYTNACNGGNACNYTNTAYACNYTNAARMGNYTNGCNTCNGTNCARGAYCAY MGNCCNCCNCAYATHCCNACNYTNCARGCNGCNGGNCARATHGGNTCNACNGARGARGAY CCNAARATGACNYTNYTNGARAAYATHMGNGCNYTNGTNCCNGAYCAYGAYMGNMGNGTN CARGARATGGARGCNMGNGARGCNGCNMGNGARMGNAARMGNAARATHAGYACNCARAAR GARGCNYTNAARTTYGGNAARAGYYTNGARATGGCNACNAARGGNYTNMGNCCNACNTCN ACNAGYAGYGARMGNMGNTCNGCNMGNAGYGCNTTYTCNAGYGCNTGGGTNTCNCCNCCN TCNTCNCCNCCNAARGCNAAYCCNYTNTCNGTNGCNCARGTNACNTCNGGNGGNACNATH AAYYTNGTNYTNTCNGGNGTNGCNAGYCCNAARTCNCCNACNAAYCCNGGNACNTTYACN ATHACNGCNCCNACNGARGTNGAYACNTCNTCNCCNGCNCCNGCNTCNTCNYTNACNTCN TCNACNAARTCNGAYACNCCN---------AARAARGTNCCNCCNCCNCCNCCNCCNMGN AARGGNAGYMGNCCNACNTCNACNAAYYTNACNTCNATHAAYGGNGTNGARCARCCNATH GARGCNMGNCAYCARTCNGARGARAGYCCNCCNCARTTYGTNGGNGGNGTNYTNGGNCAR CAYMGNYTNTCNGGNGGNCCNYTNTCNTCNACNCCNAARCCN---GCNTCNCAYAARGCN YTNTCNACNTTYGARMGNGAYYTNGCNTCNGGNATHTAYGCNAAYATGAAYMGNCCNGAY YTNCARAAYCARTCNTCNTCNCCNCARCARATGATHGAYAARGCNAGYMGNTCNAGYAGY ACNAGYAAYAGYTCNACNGARAGYAAYCARACNCCNYTNGTNACNACNTCNTGYGTNGAR AAYMGNAAYGARMGNGARAGYAGYAGYGARAGYAAYAGYAGYTCNGGNGCNAGYAGYATG GGNTCNCARCARTCNGTNGCNACNGTNGCNMGNTCNGTNTCNGTNAAYYTNMGNAGYTCN AARCCNAARCCNGARCCNCCNAARMGNCAYTCNAGYYTNYTNGGNMGN---GAYCAYCAR ACNAARAARCARGARAAYGTNGAYCCNTTYTAYAARYTNAARGCNGGNATGTTYYTNACN ACNGTNACNGGNTGYTCNGTNYTNGCNGGNTTYGGNTTYACNYTNGGNATGGCNAARAAR AAYGAYCCNAARAAYTTYGCNAARGGNGTNATHGGN------GARYTNCCNGARAGYGGN GTNTCNYTNGCNACNMGNGCNYTNGGNMGNGCNACNYTNTAYTCNGTNACNGGNTTYGGN YTNTTYTGYTTYGCNGTNTGGAARATGATGGGNGTNAAYAAYATGGTNGARTTYMGNGAR AARGTNGGNAAYGCNYTNCCNMGNYTNAARAARACNGARAGYACNGGNMGNAAYGARTTY GCNACNATHMGNGAYYTNTTYAAYTAYATHATHGAYGARGAYAARAARGCNAARGCNATH AARACNGAYAAYGARGARGAYGARTGYGARYTNTAYAARCARMGNTGYAAYAGYYTNAAY YTNGTNGTNCARGGNTTYMGNAARGARYTNACNATGTAYCARAAYMGNTGYAARGGNGTN GAYACNYTNTCNYTNATHYTNAARGARACNMGNCARGARAAYATHAARYTNTCNAARCAY ATHAARGCNATGGARACNTCNATHTCNATHYTNCARAARMGNYTNGARAARCAYGGNYTN TCNAAYAGYGTNTAYACNCARGAYACNGARYTNTTYGTNCCNGGNGCNTCNAARCARACN YTNGAYAAYYTNGTNAARGARAAYGCNMGNYTNMGNACNYTNYTNAARCARGARAGYGGN CAYYTNACNAARAARCCNTCNGAYGARATHGARGARATGAARACNGCNYTNGARGARGCN ACNGCNGARATHGARCARATGAARAAYAARYTNMGNGTNGCNGAYGAYACNAARATHATG YTNGARATGGAYTAYGARTCNGARYTNAAYACNAARYTNGARAARGGNYTNCARGARMGN GARGARGCNAAYGTNAARAARAAYGGNGGNTCNTCNYTNGAYAAYACNGCNACNGGNTTY GARGARYTNAARGAYYTNYTNAGYAARACNGTNGARAARTGYACNATHYTNAAYGARAGY YTNCCNCCNAAYGTNACNAAYMGNCCNTCNCAYGARAARGARATGTAYGARAAYACNYTN GTNCCNCARGTNAGYCARGARAARTAYAARGARYTNGARGAYAARTAYCARGAYGCNGTN AAYATGAAYCARCARTGGCARMGNTAYAGYMGNGARMGNGARAARCARATHCARGTNYTN AAYGAYAGYYTNCARGARMGNGCNGAYCCNAARCARTTYGCNGAYYTNGTNCARGARGCN TGYAAY---------CARMGNATGGTNCARTAYAGYGAYGARYTNAGYYTNAARGAYMGN GARATHACNAAYYTNCAYAARCARYTNAARACNATHGCNAGYCARYTNAAYGARGCNMGN AARTCNCARATHCARTCNCAYCAYGAYACNAGYACNGTNGARATHYTNAARCARCARATH CARGTNTGYACNGARGAYTTYAAYACNGARMGNAARGAYMGNGARCARGCNGTNAARMGN GARAARGCNGCNMGNGARGARAAYGARMGNYTNAARGTNGARATHTCNAARYTNMGNATH GARATHGARMGNYTNACNAARACNYTNGAYCARCAYTAYGTNGTNTGYTTYATHTCNTTY CARGARAAYTCNYTNGAYYTNTTY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AGYAGYATHGTNTGYCAY GGNTGY---------CARTAYCAYAARTGYGGNGAYTGGTAYGAYACNTCNGARTAYAGY GGN------AAYATGGGNGAYTGYGGNGAYGGNATGTAYTGYGTNAARTAYAARACNATH GTNTGGATHCARGAYTCNGGNGARATHAARGGNAAYCARMGNGARTCNCAYGTNGTNACN MGNAGYTGYGARTCNTCNAARGGNCARTCNGARMGNTGYGTNGGNTGGCARAAYAAYGGN GGNGTNACNYTNAARTGYTGGTGYGGNACNGAYGGNTGYAAYAGYGGNACNTCNATGAAR CCNGTNGCNYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARGARTTYCARGAYMGNTGYGARTCNGARAAR MGNGARTTYAAYAAYMGNYTNAARTCNYTNAAYCARAARCAYAGYYTNYTNCARAGYCAR AAYACNGARATHGARGCNGAYTAYATGAARYTNAARCARGAYATGGARAAYYTNMGNGCN GARCAYATGCARACNGARAGYCARCAYGCNCARGARTAYCARACNYTNAARCARACNAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TTYTTYATHATGATHGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TCNGARGGNGARGAYGARCCNYTNTTYGARATHGCNCCNGARGAYAAYTCNGARMGN ATHTTYAARGCNAGYAAYCCNGGNGARTGYCAYMGNMGNYTNYTNMGNGCNATHAAYGAY GCNMGNTCN---GARGTNGTNTCNACNACNACNACNGGNYTNGAYTTYTTYGGNYTNTCN CAYTCNGTNYTNCARAAYYTNATHCARTCNATHCCNGGNGCNMGNAARTGYTCNAARTAY AARTGGGTNAARTTYGARATHGAYAARTCNCARACNAAYGCNAAYTAYGCNATHGGNAAR AAYGAYCCNACNATHAAYTAYGARGCNTTYATGAARCAYMGNAAYGCN------------ ------------------------------------------------------------ ------------ATGAAYTTYAGYGTNGARTCNGTNYTNGARGCNGGNGGNMGNYTNGGN AARYTNACNCARATGGTNCARGGNAARGCNGTNACNYTNGARACNCCNATGTGYACNYTN TTYACNAARGGNGGNAGYGCNCCNCAYYTNAGYYTNGCNATGYTNGARMGNATHAARCAY ACNCCNAARYTNGCNACNATGAGYATHAAYTCNTTYGTNGARCAYGTNGAYAGYATHTCN GGNAGYAARAARMGNYTNGCNGAYTTYACNTCNATGAARGAYAARATGGTNTTYGCNACN YTNCAYGAYGCNAGYYTNCCNATGAARTCNGGNAARAAYGARMGNGCNGGNGTNGCNATH TGGGGNAARGGNGGNAARACNYTNYTNAAYCCNGCNACNTAYATHAARATHCARGARACN YTNCARGCNGAYTGGGTNATGGCNYTNAGYGAYGGNGAYACNGAYAARGAYACNACNGAR AARMGNAAYGGNAARGCNGTNGAYMGNACNYTNGAYTTYYTNGAYGARATGGTNACNGCN TGGAGYAARAGYGARYTNYTNAARAGYTCNACNYTNYTNGGNTCNATHGTNGGNGGNTTY AGYGARMGNCAYMGNGTNMGNAGYGCNACNGARACNGCNACNMGNCCNGTNCAYGGNTTY YTNYTNGARGGNTTYCARAARGGNCAYACNGARAARAGYYTNTTYGARGAYAAYTCNTTY CCNAAYATHYTNTCNAARACNYTNAGYCAYYTNCCNGCNAAYAARCCNMGNATHATGGAR ACNCCNTGGTCNCCNTTYGAYGTNATHAARGGNTTYAARYTNGGNATHGAYGTNTTYTCN AGYGCNTAYCCNCAYACNYTNACNGARAARGGNCARGCNATGACNYTNGARTTYACNYTN CCNCCNGCNTCNTCNACNGARAAYYTNGARAARGARAAYAGYMGNCCNACNACNCARGAY AARCCNGTN---YTNGAYYTNAAYGARAARAGYTTYTTYGAYGAYTTYGGNCCNGTNYTN GARGGNTGYCARTGYTAYACNTGYTGYACNTTYACNMGNTCNTAYATHCAYCAYYTNYTN AAYACNACNGARYTNYTNGCNTAYGTNYTNYTNACNATHCAYAAYTTYGARMGNTAYTTY YTNTTYTTYCARACNYTNMGNCARACNATHAARGAYGGNMGNTTYGARGARTTYGARGAR ATGYTNMGNAARCAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYCARTTYACNTAYACNTCNTCNGARATG ACNGARAARGCNTTYGGNYTNGARMGNGAYGAYGAYGARGTNAAYYTNGCNGAYGAYATG AARGARGARMGNMGNCARATHAAYAAYYTNTTYAAYTAYGARTCNATGGARCARYTNTCN TAYYTNYTNGAYCAYTAYMGNCARATGAARGTNAAYATHGCNGGNCCNAARGCNGCNAAR CCNGAYAARTCNYTNGAYGTNGTNCARGGNTCNATGGTNGARAAYYTNATHTCNATGYTN CARAAYTTYAARACNAAYGTNTCNAGYATHTAYAARCAYGGNTCNACNAAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARGCNCARTCNGARAGYCARGARTTYTCNAARAARACNGARCARAARYTNMGNMGN TCNATGGARATHMGNMGNGARAAYMGNGARACNCARATHMGNGCNYTNCARGARMGNYTN MGNGARCAYTCNGTNMGNGTNCAYGAYGTNCARAARACNGGNCAYGARATGGTNAARGAY TTYGARACNAARGCNGARCARAARYTNAAYCARAARATGGARACNTAYGARGARAAYMGN AARAGYCARYTNTGYTCNATGYTNCARAARYTNCARGARCAYGCNTAYCAYATHAAYGAR GTNTGYAAYGCNAGYGAYAGYMGNGGNYTNAAYACNGAYGARYTNCARGARCARYTNGTN CAYAARATGGARAAYGCNYTNAARAAYMGNGARGARCARYTNMGNYTNATHCARGAYMGN YTNGCNGARCAYGARAAYMGNATHAARGARGTNCARAARAARAARGGNATGGTNTCNTCN GGNGARCCNATGMGNTAYAAYTGYCAYYTNTGYTCNGCNACNYTNAGYTCNYTNTTYTTY YTNMGNCAYCAYYTNGCNYTNCAYGGNGGNTTYMGNCAYYTNACNACNATGTCNACNAAR GAYGGNYTNYTNATHTGYGCNCARTGYGGNTAYATHGCNMGNAGYAGYCARGARYTNGCN GAYCAYGTNGGNATHCAYGCNACNGAYMGNMGNTAYAARTGYTCNATGTGYGAYTTYGAR GGNCAYAARAARGGNATGATHGAYATHCAYATHATHMGNAARCAY---GGNGGNACNTGY GCNAARGTNGTNGAYMGNGARAARTGYAAR------GAYATGAARYTNAARGTNGTNAAY YTNTTYCCNMGNGTNATGTAYAGYCARACNTAYCAYGGNGCNACNCCNCCNCCNTAYCAY CCNTGYTCNGTNAARCARTGGGCNTCNMGNYTNYTNAAYTAYTCNTCNCARTAYAAYTCN ACNGGNTGGTCNGCNTGYCARGTNGTNGGNGARCCNAARGTNTAYCCNMGNTAYGGNGAY ATHGARGGNGCNTGGGCNCARGGNMGNAAYGAYMGNAAYGARTAYGTNGARATHGARTTY GAYGTNCCNGTNMGNCCNTCNAGYGTNCAYATHTAYGARACNTAYAAYGCNGGNGCNGTN ATHAARATHAARGGNMGNAAYGGNACNGAYCCNTGGGCNGTNYTNTGGCARACNGAYMGN CCNAARCARYTNTCNTCNAGYMGNATHTTYTCNCCNCCNYTNMGNGGNTCNATHCARAAR ATHAAYCARYTNMGNATHGARYTNGAYTGYTCNYTNGCNGGNAAYTGGTGYGARYTNGAY GCNATHCARYTNGTNGGNATHMGNGAYGGNGCNGTNCCNCCNGCNGAYGAYACNCARTAY TTYGARGAYATGGGNYTNYTNGTNAAYAAYGARTTYTTYAGYGAYATHACNTTYAARYTN GGNGGNAAYAARGTNTAYGCNCAYAARGCNATHATHGCNGCNMGNTCNCCNTAYTTYGCN AARYTNYTNAARAARAAYAARGARCARACNGTNCARYTNGAYATHTCNTTYYTNGAYCAY AARGAYTTYYTNGTNGCNYTNMGNTTYYTNTAYACNAAYMGNYTNCCNTCNGAYATHTCN ACNAAYTCNYTNGCNGCNATGTGYAARGCNGCNTCNYTNTTYGARATHCCNGARATGAAR ACNGCNGCNATGTAYAARYTNGTNGGNGGNYTNAARACNGAYAAYGTNGTNACNATHATG ATHCARGCNAGYGAYGAYCCNTCNTTYGAYGARATHMGNAGYYTNTGYATGAGYTTYATG GCNTCNCAYYTNAARGARATGTCNAARGARCCNTCNTTYGTNAARYTNCCNCARAGYACN YTNGTNGCNGTNGTNCARGARGCNACNYTNTCNYTNCARYTNAAYGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATHATHTCNACNAGYYTNCCNYTNCARGTNCCNGTNTCNCCNCCN CCNGCNGARYTNAAYYTNTAYCCNCAYATHCAYGGNYTNCCNACNCARMGNTAYATGTTY GGNYTNCCNTCNCCNYTNYTNCCNTCNATHAARYTNCCNATHAARATGGAYTTYGAYGAR CCNACNAAYATHCARGAYCAYYTNTAY---GCNTAYAGYGAYTGGGAYAAYCCNMGNCCN GGNTCNYTNGCNGCNCARCAYCARCAYCARGCNCAYCCNMGNYTNTCNGGNYTNACNTCN GAYYTNYTNCCNCCNGCNCCNGTNGTNGAYGCNGTNCCNGCNTTYTCNTTYGARGCNYTN AGYYTNAAYACNYTNAGYACNCARCCNYTNGCNAGYACNAAYGAYGTNTTYAARGCNGTN AAYGGNAARACNAAYGARAGYTTYATGTCNCCNYTNATHAGYCAYAAYACN---GARGGN AGYTCNGTNGAYCCN---GCNAARCCNYTNGAYTTYTCNTCNTTYYTNAARATHCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TCNAAYMGNCCNAGYTGGYTNACNGARAARGAYYTNGARCAY TCNAARGAYATHAAYATHYTNGGNYTNAAYGARCAYGGNAGYTAYAAYMGNGAYAARTAY GARAARAARCCNCARGTNCAYAAYTAYAGYYTNATHGGNGAYGTNYTNGCNCCNAARATG GAYTTYAAYTCNGCNMGNAGYAAYGGNGARGAYAAYCARTCNGCNYTNGTNGGNACNAAR TCNAAYGTNGCNTGGGGNCCNGGNMGNCAYYTNCCNCAYGARYTNATGGAR---AARCAR CARCARGARTCNAARTCNAARGCNAARAGYGTNATHGAYYTNCCNCCNAAYATHMGNCAY YTNTTYGGNAGYMGNGTNTGYGAYTCNYTNYTNTCNGAYCARGCNATHGTNTCNYTNGCN YTNGARMGNCARAARTCNAARATGGGNCCNYTNMGNCCNTCNAARATHCARAAYGTNGAR GGNYTNCCNGTNGAYYTNGCNAAYACNTAYGARAGYYTNGGNCAYACNACNMGNCAYAAY GTNTGYCCNGGNGTNAGYTCNGGNCAYYTNATHAGYMGNACNAARGAYGARTTYAAYGAY GARGTNCAYCARMGNMGNGTNCCNAAYCCNGAYGTNTAYMGNTAYCARMGNGAYGARYTN AGYNNNATHTGGGTNGARCARGAYGTNYTNMGNAARMGNATGGARCAYAARTGGAGYAGY TAYTTYAARTCNMGNCCNAARACNCARCARAARCCN------------------------ ---------AARCARAARGARCCNCCN------------CCNCCNCCNGAYGAYGAYATG AAYATHGTNTTYGTNACNCCNCCNYTNACNCCNYTNCCNCCNGARCCNGARATHGTNGAR ATHCCNAARGCNTTYGARMGNGAYGAYGCNTTYTGGAGYTTYTAYGAYCAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATHCCNTTYATGTGYAGYATGTGYCARATHGARYTN GAYTGYCARTAYCAYGGNTGYMGNCCNCCNTTYGCNAARGAYACNGTNYTNCAYGARGAY TGYTAYGTNATGAARGAYCCNTTYTCNTCNAGYGGNGGNTTYGTNTCNGTNGGNGGNAAR TGYTCNCARTGYAGYCARACNGTNTGYATGGCNTCNACNTGYAGYTTYTTYTAYACNACN MGNTTYTGYYTNAARTGYGCNAGYGAYGARATHGAYGARTTYCCNCCNGARYTNCAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------GGNTCNAAYYTNTGYTTYCAYGTNGTNGGNMGNGGNAGYGGNGAYATGAAYCCN ACNGCNCARGTNTCNGTNGTNCARGGNGGNACNGGNGCNAARAARGAYTAYGGNATHGCN YTNGGNAARTCNATHYTNTTYTAYGCNGCNCARMGNTCNGGN------AARYTNGCNAAY AAYCCNAARTGGMGNGGNGAYTCNGCNYTNGGNGAYTGYGTNGTNGGNGGNTGGTAYGAY GCNGGNGAYCAYGTNAARTTYGGNYTNCCNATGGCNTCNTCNGCNCAYYTNYTNATHTGG AGYGCNATHAARTTYAARGAYGGNTAYACNAARGCNGGNCARATGGAYATGATGTAYGAY TCNGTNAARTGGGTNYTNGAYTAYTTYAARAAYGCNTGGAAYGARGGNTCNCARGARYTN GTNGCNCARATHGGNGAYGGNAAYGCNGAYCAYGCNTTYTGGGGNMGNCCNGARGAYATG ACNATGAAYMGNCCNTGYCARAARATHAAYGGNGGNAAYCCNGGNAGYGAYATHGCNGGN GARACNGTNGCNGCNYTNGCNGCNGGNGCNGTNYTNTTYAARGAYAARGAYCCNGCNTAY TCNCARCARYTNATHAGYAARGCNAARAGYYTNTAYGCNTTYGCNAARGCNCAYMGNGGN GTNTTYMGNGGNAGYGCNCCNTTYTAYGGNTCNTCNGGNGAYAARGAYGARATGTGYAAY GGNGGNGTNTGGYTNTAYMGNGCNACNAARGAYAGYCARTAYYTNAAYGAYGCNAARGCN AAYGGNGAYACNGGNACNGCNTGGGCNYTNAGYTGGGAYGAYAARMGNATHGCNTGYCAR YTNYTNYTNTTYGARGARACNAARGAYGGNGGNCARAARTCNGCNGCNGARTCNTTYTTY AAYTCNTGGYTNCCNGGNGGNGGNATGACNTAYACNCCNTGYGGNYTNGCNTGGMGNGAY AARTGGGGNGCNAAYMGNTAYGCNGGNAAYGCNGCNTTYGCNGCNYTNATHGCNGCNGAR GAYGGNATHATGTCNGARAARYTNMGNCCNTGGGCNGTNGARCARATHAAYTAYYTNYTN GGNGAYAAYMGNCAYAAYGGNGGNTGYTTYAGYTTYGARATHGGNTTYGGNTCNAARTAY CCNATGCAYCCNCAYCAYMGNGGNGCNTCNGTNACNGGNAAYGTNYTNCARGGNGCNYTN GTNGGNGGNCCNGAYTCNAAYGAYAAYTAYAAYGAYAGYCARGAYGAYTAYGTNATGAAY GARGTNGCNACNGAYTAYAAYTCNGGNTTYCARGGNGCNYTNGCNGGNATHGTNCAYYTN CARGCNGCNGGNAARTTYCCNGCNACNTCNAAYAARTGYCCNTGY--------------- ---GARYTNCARACNYTNCAYACNTCNTTYCCNAAYCARACNCCNMGNTTYTGGAAYACN ATHTCNGCNTCNGCNMGNCAYGTNTTYTTYCCNMGNGAYCCNTGYTAYCCNAGYGTNATH YTNATHGCNTCNCAYGCNAARCAYAARCAYYTNACNTCNTGYATHGCNAARAARGTNTCN GGNATHTTYTCNAAYTCNCARGGNYTNTCNTCNACNTCNYTNGAYACNGAYATHGAYGAY ATHCARCAYTTYCARCCNTCNAARCARAARGARYTNYTNGAYGARCARYTNAAYYTNGCN TTYACNAARGCNGGNAARAARTCNATHGTNATHAGYAAYGTNCAYGTNYTNTCNCCNCAR GCNGCNYTNYTNYTNCAYGGNTTYTGYGAYGGNGAYAAYGCNCCNTTYMGNGAYGTNATG ATHATHYTNACNTTYGTNGTN---------GARGAYTCNTTYGARTTYTCNTCNGTNAAR CARGTNGARGCNAARYTNACNCARATHTGGGARCAYGGNYTNCAYGCNGAYAARYTNGCN GCNYTNATGAGYMGNATHGCNAAYAAYCCNGTNGTNGTNATGAARGARGARGCNACNGCN GTNGARAAYATGTGYGTNGCNACNAARACNGARAARTGGYTNTGYYTNGARYTNGGNAAR YTNGGNATHGAYTCNACNGAYGARAGYGCNMGNTAYATHYTNTCNATGGARTCNAGYAGY GAYYTNGARGARTAYATGYTNGARYTNYTNGAYGGNGCNAAYCCNAARGTNMGNTTYTTY ATHCARGARYTNAARGAYMGNTTYTCNACNAARGGNAARAGYAAYAAYGTNCARGCNTAY MGNAARGAYAARGGNGTNGARTCNTCNGARGARAARTCNAARAARAARAAYAARTCNACN CCN------------AAYCARACNAAYGCNAARAAYAARCARGCNTCNAAYAARAGYAAY TCNTCNAGYCARCARGGNGARAARAGYYTNTCNGGNTAYCARAAYAAYGTNCCNCARCAY TCNGGNGARATHGGNGTNGGNGCNAARAARAARACNAARTAYGTNCCNYTNTAYAGYAAR GARGGNCARGARAARTCNGTNGTNCARYTNCCNGGNMGNCAYMGNTGYGAYTGYCARGCN TCNAARCAYMGNYTNGTNAAYAAYTGYGTNCARTGYGGNMGNATHGTNTGYTCNCARGAR GGNTCNGGNCCNTGYGTNTTYTGYGGNACNYTNGTNTGYACNCCNGARGARATGGARGTN YTNGAYMGNGGNTCNMGNAARGCNGARMGNYTNMGNGARCARYTNYTNAAR---GGNGGN AAYAARYTNAAYGGNYTNAGYGARACNGGNCARTCNYTNYTNCCNATHGGNTTYAAYAAY CARGCNMGNGARGAYGARGARAARGCNYTNAARCAYMGNGAYAARYTNYTNGAYTAYGAY MGNACNAGYGTNMGNMGNACNCARGTNATHGAYGAYGARTGYGAYTAYTAYGCNACNGAY ACNAAYMGNTGGYTNAARAARGARGARMGNGARAARYTNMGNACNMGNGARGARGARYTN MGNCARTCNMGNTTYGGNTCNMGNMGNGARMGNAARATHACNTTYGAYATHGCNGGNMGN AAYGTNMGNGTNYTNGAYGCNGARGARGAYGCNAGYAARACNATGTAYGAYAAYCARGAY GCNGTNATHCARGAYGTNCAYTAYGGNAARGGNCCNATHAAYACNGARCAYTCN---AGY YTNGCNAAYCCNTCNTTYGARTTYGARCCNAARTTYYTNYTNGAR---AAYGCNCCNGTN GARTGGGGNCCNAGYYTNTCNAARCCNGCNTCNAAYGAYCAYAAYCCNCARGCNATGACN AAYMGNATHCARGAYMGNGARYTNCARGARATGAGYGAYCARGGNATGTGYATGAGYATG CAYCARCCNTGGGCNTCNYTNYTNGTNTGYGGNATHAARATGCAYGARGGNMGNTCNTGG TAYTCNCARCAYMGNGGNMGNYTNTGGATHGCNGCNACNGCNAARGTNCCNGAYAARGAR GARATHYTNGAYYTNGARCARTTYTAYAARCAYCAYTAYGGNGGNTCNCARYTNAAYTTY CCNAARGAYTAYCCNCAYGGNTGYYTNYTNGGNTGYGCNAAYGTNGAYGAYTGYATHGAR CARGGNCARTAYMGNGARAARTAYCCNGAYGGNGARTCNMGNTCNCCNTAYGTNTTYGTN TGYTCNAAYCCNTCNCARYTNYTNGTNAARTTYCCNATGAARGGNAARCAYAARATHTAY AARYTNGAYGCNCAYATHCAYCARGCNGCNAARAARGGNYTNMGNTGGAARGCNMGNTGY AARYTNTGGGARCAYAARGAYGGNAAYYTNTAYTCNTCNTCNGGNACNGCNCCNGCNCCN TCNAARAAYTTYGTNCARATHGTNGCNACNGAYATHGARATHATGTTYMGNGTNTGGAAR ATHYTNCCNCCNACNMGNGCNGARTCNAAYCARCCNCCNGTNCARATGAARTGYYTNTAY GCNGARTTYGCNGARGAYGCNAARATGMGNAGYGARATHGARMGNTCNYTNGGNMGNCAY GARYTNAAYTAYYTNGAYMGNYTNGTNGARAAYCAYYTNGAYTTYATHGTNMGNACNCCN MGNAAYYTNYTNYTNAARGTNYTNTAYTAYYTNGAYYTNGTNTCNATHGCNAARYTNAGY ATGACNTGYAARTTYTTYATGGARYTNTGYTCNTGYGAYGCNYTNTGGTCNAARATHTAY ATGGARACNACNAARAARCCNATHACNCARGARYTNYTNATGGTNGTNGAYCARAARGGN TGGAARGARGTNTTYTTYATGAAYAARYTNCARYTNCARATGCARATGMGNMGN---YTN GGNGARCCNTCNAARGARTCNMGNTTYTTYTAYGGNAAYAARTTY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TGYCAYGCNGAYYTNACNTTYTTYGCNYTNMGNCARTTY GTNCARAARMGNYTNACNACNAGYAAYTGYAAYAARACNGGNAAYATHGTNAARCCNTCN AARAARAARAARCCNYTNYTNATHCCNGARATGTGYAARTTYCAYGGNAARAARTCNYTN AARCAYTGYGCNYTNTTYGGNGAYCCNCAYYTNMGNATGTTYAAYGGNGAYTTYCARACN TGYMGNATHGARGGNGCNTGGCCNYTNGTNAAYAAYGAYTAYYTNACNGTNCARGTNACN AAYCAYCCNGTNGARGGNAAYCAYGAYGTNACNGCNATHAGYAARYTNACNGTNATHGTN AARGGNAAYTCNGTNTGYACNACNAARAAYTTYCARACNTAYCARGCNCARTCNAAYTAY YTNCCNGGNACNTTYGTNGAYGGNAARAARGARTAYGGNAAYTAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TCNATHYTNGGNYTNATGAGYYTNTCNYTNYTNTGGAAR ACNTAYYTNATHTCNTTYGTNTTYACNTTYGCNATGTCNTTYACNTTYGCNYTNATHAAR ATHTTYCAYACNGARCARYTNGARTTYCCNGTNACNAGYYTNATGGARTAYTCNAAYGAR AARACNYTNCCNGAYGCNYTNGCNTGYACNTAYTCNCCNYTNYTNCARCAYYTNGCNTAY TAYGAYYTNGCNTGYYTNAGYAARTAYGTNTCNCARMGNATHCARGAYYTNYTNTGYYTN AGYCARCCNGGNGGNCAYCCNAARGTNTGGATGATGGTNAGYGGNTCNGCNYTNTCNACN ATHCARGARYTNACNAAYCARGTNAARGARGARAAYTGGTCNATHATGTCNMGNGTNCCN ATH--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATHTTYATGGTNCAYYTNATHCAY MGNGGNTTYATHCAYCCNTTYATHATGMGNTAYAARAGYGCNAARGTNCCNYTNGGNATH TGYYTNGGNGGNGCNGCNCCNAAYTTYYTNTAYCARTGGYTNATHGCNAAYCAYATHGGN GTNGCNCARTAYTTYAGYAGYTAYCCNTAYGAYCCNMGNTTYATHYTNGGNGTNYTNYTN TAYGTNGTNGGNTTYATHATHAAYMGNTGGGCNGAYTGGAARYTNMGNTCNYTNMGNNNN NNNNNNGGN------------------TCNAARGGNTAYTAYATHCCNTAYGGNGGNYTN TTYAAYTTYGTNGTNAAYCCNAAYTAYTTYGGNGARYTNGTNCARTGGATHGGNTGGACN YTNGCNACNTTYTCNYTNTCNGGNYTNATHTGGGCNYTNTTYTCNGCNGCNACNTTYTTY GCNMGNTCNMGNCAYAAYYTNAARTGGTAYCARAAYCAYTTYGARGAYTTYCCNCCNAGY MGNAARGCNYTNATHCCNTTYATHTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ACNYTNTGYACNYTNTGYACNACNYTNGAYGARCAYMGN AARCAYYTNCARMGNATGMGNATHCCNAARAARATHCAYGCNCCNAARCARACNATHCAR TAYATHGCNCCNMGNCCNMGNGTNAARCCNGARCCNAARGARCCNGAYGAYCAYTTYACN GARMGNTAYAARGTNATHGTNTGGACNGGNAAYCAYACNGARGCNTCNACNGAYGCNAAY GTNTAYATHAGYYTNMGNGGNGAYGARGAYACNYTNYTNCCNACNYTNYTNTGYMGNGGN CAYTCNAARAARAARATHTTYTTYGCNCCNGGNTCNAARGARACNTTYTTYGTNAARGGN CCNGARYTNGGNAAYYTNCARYTNYTNGCNATHGARCAYGAYGGNATGGARAARAARCAY GGNTGGTAYTGYGARAARGTNGARATHACNTGYATGMGNACNYTNCARCAYTGGGTNTTY ATHTGYAARAAYTGGYTNTCNYTNCAYCAYGGNGAYTTYAGYYTNACNMGNACNYTNGAR GCNAARTAYYTNGARAARAAYAARYTNTTYGARAARGGNAGYGTNGAYAARTTYMGNTTY AGYATHAARGAYATHGGNACNATHCARTCNATHMGNGTNGARCAYGAYGGNMGNGGNATH GCNGCNGGNTGGTTYYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGCCNATHTTYMGNATHGARACNAAYYTNTCNAARAGYGARATHCCN GARAAYGTNYTNCARGARGCNACNAGYYTNATHTCNTCNGARYTNGGNAARCCNGCNTCN TAYGTNTGYATHCARGTNTGYCCNGAYCARGTNATGAGYTTYGGNGGNTCNAARGARCCN TGYGCNAAYATHACNYTNAAYTGYATHGGNGTNGTNGGNCCNGAYAARAAYMGNAARATG GCNCCNATHYTNTCNAARTTYATHGARCARCAYYTNGGNATHAARCARGARMGNTTY--- ------------------------------------------------------------ ---------------------------------------AGYGGNCCNGARCCNCCNGAR AAYACNAARYTNGTNACNGCNTCNTTYTCNYTNTTYCCNAGYYTNATGCCNGCNMGNYTN TAYAAYGARGCNTTYTCNAAYTTYTAYCAYTTYAGYMGNATGATGCAYAARGTNGCNYTN GAYCAYGARTTYYTNAARGARAGYATGAARAAYGTNATHGGNGTNGAYGAYTTYTCNAAR AAYYTNTGGGAYATHTAYGTNAARGTNMGNGARAAYGGNGTNAARCARCCNATHATGYTN GGNYTNGTNMGNAAYGAYTTYATGYTNAAYTGYCAYGAYCARGARAAYGCNYTNAARAAY YTNAGYACNGCNGAYYTNCAYYTNAARCARGTNGARTAYAAYACNATHGCNACNAGYTTY GCNGGNGTNAAYGARMGNATHAAYCCNYTNCAYAARYTNACNYTNAARYTNGCNGGNAGY CARTAYGAYCCNAARCARAGYCCNCCNAAYAARGCNAGYAGYGGNATGTCNGCNGGNYTN GTNATGGCNTGGGARYTNTAYGGNAAYAARAARGCNATHATHGCNTTYGTNGTNAAYGAR MGNGARMGNAAYYTNATHGAYCARMGNATGATGGARTTYGAYGTNTAYGARMGNAAYCCN AAYATHMGNTGYATHTTYACNAAYTTYYTNGCNTTYGCNCARMGNGGNGTNYTNGAYGAR CARACNAARYTNACNYTNGAYGGNGAYGARGTNGCNGTNYTNTAYYTNMGNGAYGGNTAY ATHGARACNAAYTAYCCNACNCARAARCAYTGGGAYGGNMGNYTNAARATGGARYTNTCN MGNGCNATHAARTGYCCNAGYATHCARTAYCAYYTNGCNGGNGCNAARAARATHCARCAR GARYTNGCNMGNCCNGGNATGGTNGARMGNTTYGTNGAYGAYCCNAARATHGTNAGYATG ATHAARGCNACNTTYGTNGAYCARTAYAGYYTNGAYYTNGGNGARGARGGNGAYAARGCN GTNAARYTNGCNYTNGCNTCNCCNGAYAARTTYGTNYTNAARCCNCARMGNGARGGNGGN GGNTTYAAYATGTAYGGNGAYGAYATHACNAARTTYYTNACNGARCAYGCNCARAGYACN GARMGNAAYGCNTAYATHYTNATGGARMGNATHTTYCCNTTYGARCARAARAAYTTYYTN TAYAARCARGGNMGNCCNATGCCNYTNGARACNGTNGTNAAYGARYTNGGNATHTAYGGN TGGTAYATHGGNGAYATGAAYATGAARGARTAYGGNAAYGARCCNACNGGNTTYGTNATH AARACNAARGARAARAAYACNAAYGARGGNGGNGTNGTNGCNGGNTTYGCNGTNYTNGAY ACNCCNYTNYTNGTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYCCNGARAAYCCNCCNGARTAYACNGARMGNACN AAYGTNGCNACNGTNTCNGGNGARCARCCNCCNGAYTAYAAYGCNGCNTCNTTYCARGAR CCNCCNCCNACNTAYGAYTCNYTNTTYGGNAARGTNAARGCNGCNAARACNGARTCNTCN GGNGTNYTNGAYTTYTTYAARAARYTNYTNATHATHATHYTNTCNACNATHGGNGTNACN ATHYTNATHGGNATHTTYATGGCNGTNCCNGTNTCNATGATHGTNATGGGNGCNATHTAY YTNGAYGAYTGYAARGCNGARMGNATGATHCCNATHTAYYTNATHGTNGCNGGNAGYTTY GGNAGYGCNAARAAYYTNTGGAGYYTNGTNCARMGNTGYMGNAARACNGARGARGARMGN CARGARGAYCARAARAARGTNAAYCCNYTNGARAGYATHGTNAAYTGYTTYYTNTTYGCN TGGTTYATHGCNGGNTGYGTNTAYATHTAYMGNACN---AARGAYGARTTYCARTCNACN CAYAARACNCARGAYGAYTAYTGYAAYCAYACNYTNTAYTGGTAYTCNTTYTGGATHACN ACNTCNGTNTAYATHATGATGGCNGCNAGYTGYYTNTGYGTNTGYTGYGTNGGNTGYYTN GCNTCNTGYTTYGCNAAYAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNGCNGAYGCNGCNYTNMGNTGGMGNACNAARATHATHAAYGARACNGAY GARGGNCCNAARGAYGCNATHMGNGCNTTYMGNAARMGNATHTCNCARAAYGTNGGNAAR AAYTAYACNGCNGTNATGTAYTGYYTNACNTGYYTNGARTCNTGYGTNAARAAYTGYGGN MGNMGNTTYCAYYTNCARGTNGCNAAYAARGAYTTYYTNCAYGAYYTNATHAARATHATH GGNCCNAARAAYGAYCCNCCNCARATHATHCARGARAARGTNYTNAGYATGGTNCARACN TGGGCNGAYGCNTTYMGNGGNAAYCCNGARYTNAARGARATGGAYAARGTNTAYCARGAR YTNAARCARAARGGNATHGARTTYCCNATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ACNCARGGNACNGTNGAYGCNTGYYTNTTY GCNYTNAARAAYGGNTGGTGYATHAAYATGAGYGGNGGNTAYCAYCAYGCNAAYMGNYTN TCNTCNGGNGGNTTYTGYATHTAYCCNGAYATHACNATHGGNATHCAYTTYGCN---MGN AARTGGGGNGGNATHAARMGNGTNATHATHATHGAYYTNGAYGCNCAYNNNGGNAAYGGN CAYGARMGNGAYTTYYTNGGNGAYGARGAYGCNTGGATHATHGAYGCNTAYAAYCCNGAY ATHTAYCCNGGNGAYGARCAYGCNAARMGNGCNATHAARTCNTCNATHAARGTNTAYCAY TGGACNGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNGARGGNMGNGAYGTNYTNAGYYTNAARMGNYTNMGNMGNGARGAR ATHAARCARATHATHTGGACNGCNMGNGAYYTNAARACNMGNATHAARGARAAYGGNGAR ATHTAYCARCCNYTNTCNGGNMGNAGYGCNGTNATGYTNTTYAARCARGAYAAYTCNYTN AARAARGTNTCNGTNGARYTNGGNYTNTCNAARYTNGGNGGNCARGCNGTNTAYTGYGGN CCNYTNGAYATHGAYYTNAAYGGN------ATHGTNAARGAYGCNGCNMGNGARTTYGCN GGNGCNGCNGAYTGYATHATHGCNACNGGNTTYYTNCARGARACNGTNAAYACNYTNGCN AAYGARTGYACNTCNCCNGTNGTNTCNGGNTAYACNGAYGTNGARCAYCCNGTNCARGCN YTNGCNTAYYTNYTNACNYTNCARGARCAYTTYAAYTAYYTNATGGGNTGYAARGTNGCN TGGATHGGNGAYGGNAAYTCNGTNYTNAAYTCNYTNATGTAYGGNTGYGCNAARYTNGGN ATGGAYYTNAGYATHGCNACNCCNATGGGNMGNGARCCNAAYACNGAYGCNATGYTNGAR GCNATHAARATHGCNGGNAAYACNTCNGCNTCNATHCARTAYAGYAAYAARCCNGTNGAR GCNGTNTAYMGNGCNGAYGCNATHATHACNGAYCCNTGG------------GAYGAYGAY GCNAAYCAYGTNAARGARAAYMGNGAYTTYCAYGGNTTYGARGTNAAYMGNAARATGYTN AARGARGCNGGNGGNAGYTGGGTNACNATHCAYMGNYTNCCNMGNYTNCAYGGNGARATG GCNGAYGAYGTNTTYTAYGGNAARGARTCNYTNGTNTGGCARGCNGCNGARAAYMGNATG TGGGTNAGYATGGCNGTNYTNYTNAAYYTNATHACNGCNTGYACNTCNTCNATHCCNATG CCNAARTTYGTNAARGGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARGGNGARATH TCNYTNCAYAARGCNYTNGTNGCNGARATGAARAARAAYCARAARGARYTNGAYGARTTY GTNGGNGARYTNGARGARGAYGTNGARGGNATGCARGGNYTNATHYTNATGYTNCARCAR CARYTNAARGARGGNAARGARCARATHACNMGNYTNCARCAYGARAAYGARCARYTNMGN ACNYTNCARTCNCCNACNGARATHGAYMGNGGNAGYGCNYTNAAYAAYGARTCNMGNGCN GARATHGCNTGYTCNGARGAYTAYTGYAARTTYTCNACNATHMGNAAYAAYTCNATHTCN GCNMGNACNGGNGAYGGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN GARAAYGGNGGNGAYTCNGGNGAYCAYGGNGAYCAYCARGGNAAYGGNGGNMGNTCNTAY ACNCCNGAYGCNTCNGAYYTNGARGAYTTYGTNYTNMGNCCNGCNCCNCARGGNGTNACN ATGAARTGYMGNATHACNMGNGAYAARMGNGGNGTNGAYMGNAAYATHTAYCCNACNTAY TTYYTNCAYYTNGARYTNGAYAAYGGNMGNAARGTNTTYYTNYTNGCNGGNMGNAARMGN AARAARAGYGCNACNTCNAAYTAYYTNATHTCNACNGAYCCNACNGAYYTNACNMGNCAY GGNGARTCNTAYTGYGGNAARYTNMGNTCNAAYYTNYTNGGNACNCARTTYACNYTNTAY GAYCAYGGNGAYAAYCCNAARAARAGYGGNCARCARACNGCNMGNCARGARYTNGTNGCN ATGGCNTAYGARACNAAYGTNYTNGGNTTYAARGGNCCNMGNAARATGACNATHATHATH CCNGGNATGACNAGYGARCAYCARMGNGTNAAYATHAARCCNCARGGNGGNCAYGAYGGN YTNATHGAYMGNTGGAARMGNAARCAYATGGARAAYYTNYTNGARYTNCAYAAYAARACN CCNGTNTGGAAYGAYGAYACNCARTCNTAYGTNYTNAAYTTYCAYGGNMGNGTNACNCAR GCNTCNGTNAARAAYTTYCARATHGTNCAYGAYAAYGAYGTNGAYTAYATHGTNATGCAR TTYGGNMGNGTNGCNGARGAYGTNTTYACNATGGAYTAYAAYTAYCCNATGTGYGCNYTN CARGCNTTYGGNATHGCNYTNAGYAGYTTYGAYGGNAARYTNGCNTGYGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG GCNTCNTCNTCNTCNTGGGARGTNGTNAGYAAR---AARAARAGYAARGGNGAYGTNACN AAYYTNGCNCCNAAYAARGARAARGARYTNTTYGAYAARATGCCNMGNATHGCNMGNACN GAYCCNGTNCCNYTNGAYGARACNATGTAYTCNGCNTTYYTNGGNAARGARAAYAARAAR CCNTCNAAYATH------GCNAARGAYGAYGGNAARCARAAYGGNACNAARAARAAYGCN AAYCARAARAARAARAAYAARCCNGARGARCAYMGNAAYAARCCNAARATHGTNGAYYTN AAYGTNGCNYTNTCNACNYTNGAYGCNAARGAYYTNGARGGNGTNYTNACNCARTCNGAR GCNTAYTTYCCNAGYCAYCCNYTNGTNTGGYTNAARGAYYTNGCNTCNTAYYTNAAYATH AARYTNGARAAYACNMGNGAYAAYGAYCCNACNTAYAARGGNAARTCNGTNAAYTAYCCN YTNGAYGCNGTNCCNAAYGCNTGYTCNAARGTNYTNCAYACNTTYATGAARAARTTYTCN AARCAYACNATHGAYAGYATHTTYTAYTAYGGNATHACNACNATGYTNACNGARTCNTCN MGNGGNATHTCNGTNCAYGGNTAYMGNGTNTTYYTNCARYTNATHTCNCAYACNAARCCN GAYGTNGTNGCNGARAAYYTNTCNCARTAYYTNGARATHYTNMGNATGCAYCARAAYAAY CCNTCNAARTGYYTNTCNGTNYTNTGGGTNYTNGGNCARTGYGGNTTYAARAAYTTYAAY TGYGGNYTNAARGTNTGGYTNGAYYTNATGYTNCCNGCNYTNGARGTNMGNCARGTNGCN CAYTAYCCNGTNGARTAYYTNGARACNATHATHAARTCNAAYAARAARTCNACNAARAAR ------------AGYTAYGGNYTNGTNACNYTNMGNGARTAYTTYCARGTNATGGAYGTN TTYTTYAGYCCNAARTTYACNYTNGCNCAYGAYYTNAARAAYMGNYTNAAYYTNYTNTAY CCNTTYATHAARACNYTNGCNTAYGGNGARACNCCNTCNCARAAYYTNMGNACNTTYTTY CCNTCNTAYYTNAGYMGNTTYAGYACNACNAGYTCNAARGCNATGAARGAYGARYTNYTN GARTGYYTNACNCAYTGYYTNATHACNGAYAARCARTCNTTYAGYGTNTGGTGYCARYTN TAYACNAARCAYYTNTCNGCNTCNAGYCAYYTNYTNGCNCAYYTNGTNGAYAAYTGGTCN GGNYTNCARTAYAARATGGAYAARAARGTNYTNACNGARACNYTNMGNTCNTTYATHGTN ACNAAYGARGARYTNGAYATHTCNAGYAARGGNAARYTNGAYGGNYTNAARYTNTCNCAR YTNTCNACNAARGARYTNATGACNAARYTNAAYGGNACNTCNTTYCCNTGGAGYYTNYTN GTNTTYTTYATGGTNTCNGTNTTYGCNGCNATHGTNGCNTAYGAYATHACNTCNAGYCCN TCNTTYMGNTCNTCNAARACNATGCARTTYYTNGARCAYTAYGGNATHYTNGCNYTNYTN GAYAARACNTAYCARGGNGTNAAYAAYGTNATHGTNYTNTCNGTNCARTGGGTNAARACN AAYTTYCCNATHTTYTAYGCNTCNGTNMGNGAYACNYTNGTNCCNTTYGTNATHACNGTN TGGAARAGYTCNAARGAYTTYYTNYTNAAYGCNGARATHGARTCNMGNCCNTAYMGNGAR YTNYTNGTNGARAARGCNATHCAYTTYTAYCAYTGGGTNTAYGAYYTNTCNCCNGARTTY TGGGTNMGNTGYGARGARYTNATHTGGYTNTCNTGGGAYYTNTGGAARGAYTAYTCNTAY MGNATHTGGATHYTNYTNGTNGAYYTNGCNGGNCARGCNGAYCAYTGGYTNACNGARCAY GTNYTNACNGGNTCNTTYTCNAARGARGCNATH--------------------------- ------------------------------------GAYGAYTTYTTYCARGCNTTYYTN CAYTCNYTNMGNGCNTCNTGYTTYCARTTYGTNGAYTTYMGNGAYCAYGTNAAYATHMGN GGNTTYATHTCNGTNGARGTNGAYGGNGCNAAYCAYMGNCAYYTNGTNYTNGCNGARAAR GTNGCNMGNGGNACNGCNAGYGTNACN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GCNTAYCCNGTNMGNGTNGCNACNTCNYTNTCNGAYGTNATHGCNATGTCNGGNAAR MGNTCNTCNATGYTNGCNAARTAYAARGTNGGNGTNAAYMGNGAYGGNAARYTNCARTCN GTNGAYATHCARTAYTAYYTNGAYTGYGGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CCNTTYGAYGAYATHGTNTTYGGN CCNTTYACNGGNAAYYTNACNYTNATHMGNTGGTTYCAYATGYTNAAYGARCAYTTYAAR GTNCAYGGNAARGCNTAYTTYYTNTAYAARCCNMGNGGNAARAARCARACNGCNGGNGTN ACNGCNGARATGGCNYTNGARAARYTNAARGCNGGNYTNTCNAAYMGNAAYATGACNTTY GTNTAYCAYTGY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNAAR TCNGARGGNGARGCNYTNTCNTTYCARATHTCNTTYCAYCARAARACNATHAARYTNYTN CARGAYGARYTNGARCAYYTNGCNAARGARAARGCNGARYTNGAYAAYGTNCCNAGYGGN GAYGCNACN---GARGCNAARATGAARCARYTNGARGCNGAYGAYYTNATGTTYMGNAAR TAYYTNGGNATGGARATHMGNAARGTNAARGGNGGNTGYYTNCARATHGCNTTYAAYCAR ATHGAYCAYAARCARCCNAAYTCNYTNTAYYTNTTYTCNYTNCARYTNGAYGARAAYMGN AARTAYATHGTNACNGAYTGYAARCCNGAYATHCCNGAYYTNGAYGAYATH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GGNGTNAARYTNGCN GARAARGTNATGMGNAARGAYYTNGGNGGNAARGGNGGNMGNATHATHAAYATHAGYTCN TGYGCNGGNYTNAAYACNTCNCCNTAYGTNCCNATHTAYGCNGCNACNAARCAYGCNGTN MGNGCNTAYACNACNTCNYTNTCNMGNCARTGYGAYATHGAYGARMGNGGNATHCARTAY GCNCARATHTGYCCNGAYCCNGTNGAYACNGAYATGGTNAARAGYATHGAYGCNGTNAAR ATHAAYTAYTTYGAYATHGTNAARGARAGYTTYAARGAY---ACNATHCCNCCNAGYMGN TGYGTNGARGCNATGYTNCARYTNYTNTCNYTNGAYAAYATGAAYGGNGCNATHYTN--- ---MGNAARMGNMGNTAYAGYGAYGTNYTNAAR---GAYCCNTAYAARGGNCCNCARCAR TTYYTNGARGCNGGNGTNMGNGGNTTYYTNYTNACNTGYCARCARGAYMGNGARGARTAY GCNGTNGAYGARGCNATHAARGTNYTNMGNAARACNTGYGTNAARYTNTAYGGNGGNATH AARCCNYTNAARCCNGARGAYGCNGCN------MGNGGNTAYATHATGGTNGAYTTYATG AAYCCNGARGAYATHCARTAYATHCCNCAYCCNGAYGCNGAYAARYTNGCNGARGARGAR GCNGCNAARGARACNGARGARGGNGCNAARGARGARACNGAYGCNAAR------------ ------------------------------------------------------------ ---GAYGARGCNAARGARGARGTNGARGARAARGARGARGCNGCN--------------- ------------------GCNGARGCNGARGARTCNAARCARGARGAYACNGARAARCCN GARGGNGARGGNAARGAY------------AARGAYAARGARGCNTCNCCNAARAARCCN MGNMGNGARGAR------------------------------------------------ GARMGNMGNCARMGNMGNCCNYTNYTNYTNTCNACNCAYAARTTYCARAGYTAYMGNACN GARYTNMGNAAYATGATGTTYGTNAARTCNGAYATHGCNGAYCCNGTNGARGTNYTNAGY GARGCNTTYGAYYTNATGTCNAARMGNAARCCNYTNATHGCNGAYGTNATHAAYCARATH YTNCCNGTNCARGGNGTNTGYGAYAAYGAYTAYAARCARYTNGARATHATGTGYMGNMGN GTNYTNGCNCCNTAYTTYTCNGARGARGTN---TAYCCNGARAGYTTYGGNYTNYTNTTY YTNGAYAARATGTGYGARCCNGGNGGNGARGTNYTNACNGARGTNGTNMGNAGYGCNATH TGGAGYATHAAYCCNTCNGCNTGGCARAAYTCNCCNTGGTGYGARCCNGAYGTNGTNGTN CAYGTNGARATHATHGGNAGYAARATHATHYTNTGYGCNATGCCNMGNTAYATGAARTAY MGNCARTAYAGYCCNYTNGCNGTNTAYGARYTNGGNTAYGGNAARCCNGARGAYGARGAY AARYTNYTNMGNGGNYTNAARMGNTCNGAYGARGAYGARGARAAYMGNAARAAYMGNAAR AARGAYAARGAYAARMGN------------------------------------------ GGNAARGAYAARGCNGAYGARAARACNGCNGARGARAAYAARGAYGARGCNGCNACNGCN GAR------------------------GGNGCNGARACNACNACNGCNGARGGNGCNGAR ACNACNGARGGNGAYAAYGGNGARGCNACNGARGARGCNGCNGCNGAR------------ ---------------------------------------------GARMGNGTNAARAAR ATHCARAARACNACNGARTCNAAYATHYTNATHYTNYTNTCNMGNATHTCNGTNAARACN AAYCCNACNTAY---ATHGTNAARTAYTCNGTNYTNTGYGCNYTNACNTCNTAYYTNMGN ATHTCNCCNMGNCCNTTYCARMGNTGYATHMGNACNYTNYTNMGNGTNTGYAAYAAYCCN YTNTGYTTYCARTCNYTNYTNYTNGARCARGCNCCNGCNYTNATHGTNAARAAYYTNATH YTNGAYCARGAYGGNACNTTYCCN---ACNTTYYTNTTYAARACNTTYTCNGAYGGNAGY AAYYTNAARACNGARACNCCNATHAAYTTYGAYGARATHTTYATGTCNTCNCARACNTCN GARGCNACNTCNGAYTTYGGNYTNCARATGGARTTYGARTTYGGNGAYGAYGCNTAYACN AARATGATGTTYCCNAAYTGYCCNCCNATHATGYTN------MGNMGNGCNYTNTCNGTN GAYAGYCARTGYGCNMGNGAYCCNGARGTNTTYACNATGGARACNGTNAAYAAYGCNGAR GARAARGTNAARACNCARMGNTAYGGNATHAAYYTNATGAARGCNATHACNTCNGCNGCN YTNTCNMGNTAYGGNGAYGGNGARATHCARMGNATHTGGTCNMGNGGNACNAGYTCNGAR AARYTNATGTGYGCNATHAGYYTNYTNCAYYTNCCNATHGGNTGYGGNAAYYTNCARMGN MGNATGATHYTNYTNAARTAYAAYTGYYTNGARCARGTNATHCCNYTNYTNTTYCAYMGN GARGCNCCNGAYATHMGNGARAGYATHGTNACNGGNYTNTCNYTNGTNGCNTTYYTNATG AARYTNTCNAARTCNACNGARMGNATHCCNGARYTNAARTCNTGYCCNGAYTCNTGYTCN TAYTCNAAYAARCAYTAYACNGCNGARCARAARGAYAARAAYCARAARACNAAYGARATH AGYTGYMGNTAYAARAAYATGGCNCAYMGNTTYAAYYTNAAYYTNATHGTNAGYAAYAAY GAYMGNAARGARTTYAARGTNTGYAARGARATHYTNATGAGYAARTCNGAYGTNTTYTGY GCNATGYTNGGNGGNGCNTAYGTNGARGCNGARAARCAYGARATHGARTTYAGYGAYATH AAYYTNTTYGGNTTYGARTAYATHYTNCAYTAYYTNCAYGGNTGYGARTCNGGNTGYCCN ATGATHGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ACNTAYGARGCNCAYGARMGNAGYMGNTTY ATGCARAARYTNATHAAYAARAARGGNGCNAARAAYAARAARCARTGGTAYAARCCNCAY YTNGGNGARCCNYTNGARYTNGGNCARAARAARACNAARAARGGNATHTCNGTNAGYCAY AGYATHMGNYTNMGNCARYTNAGYCAYGTNYTNTAYGAYAARATHACNGARATHATHAAY ACNGGNGARYTNTCNCARGAYGTNYTNGAYGCNCARGTNGCNATHACNTCNGCNTCNATG ACNAARGAYATGAGYTGYYTNAAYATHTAYTGGGAYGCNGAYMGNACNGAYTGGGARYTN GTNGARCARACNYTNCARTCNCAYAGYGGNAARYTNMGNAGYYTNYTNATHTCNTAYCAY ATHYTNGGNMGNATHCCNCAYATHGCNTTYGTNAARAGYAARGCN---GGNGCNAAYYTN AGYCARYTNAAYCARYTNTTYGAYATHGCNGAYTAYGGNCCNGAYTAYATHCCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CCNATGCCNGCNGGNTGGGARGCNMGNTGG GTNCCNGGNCARAAYMGNTAYTTYTAYATHAAYCAYTCNACNAARACNACNCARTGGGAY GAYCCNMGNCAYCARCCNCARCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ACNCCNGGNAGYCCNTCNYTNAGYCAYCAYGCNTGYGTNGTN AGYGARGAYMGNTAYATGATHYTNATHGGNGGNTGGAAYGGNAARMGNMGNAGYTCNGAR GTNGCNGTNTAYGAYACNCARGARAAYGARTGGYTNTCNATGACNACNAGYGGNTTYCCN GARGGNGCNGGNYTNAGYTCNCAYACNGCNGCNATGYTNAAYAAYAGYGAYATHYTNGTN ATHGGNMGNGARGGNAGYYTNMGNATHCARMGNAARTAYGGNAAYGCNTAYATHYTNCAY GGNAGYGTNYTNTCNGGNCAYTTYTCNTTYMGNGARTAYAGYAAYAAYGTNACNTCNMGN TCNGGNCAYACNTCNGAYGTNATHAGYCAYTCNGTNTTYATHGTNGGNGGNMGNAAYGAY AARYTNYTNGARAARGCNCARGGNTTYMGNCCNGCNGTNCARCARACNTGYTCNATHYTN TCNTCNATHYTNAARACNATHACNACNAAYAAYCCNMGNCCNATGGCNAARYTNCCNTGY GGNMGNAARAAYCAYATHTCNGCNTCNGAYCARCAYTGYATHTTYATHCAYGGNGGNGAR ACNTTYGAYGGNMGNAGYMGNGARCCNGTNGGNGARATGTTYATHATHACNYTNGCNTCN CCNACNAAYTTYTAYAARYTNAAYACNAGYAGYYTNAAYMGNGCNGGNCAYGTNTGYTGY GTNTCNCARGAYAAYGTNTTYATHCAYGGNGGNYTNAGYGGNMGNTCNATGATHAAYTCN GAYYTNTAYCARYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GCNGARGAYTGYYTNYTNAAYYTNGARGAYMGNATH GAYTCNYTNTCNCCNTCNGGNGARTAYATHAAYGCNYTNGAYACNGARATGYTNYTNYTN AARGCNACNTCNGCNGCNACNYTNMGNTGYATHCARGAYTGYATHTCNYTNYTNCARAAY GCNGARNNNAARGARCAYAGYAAYCARTCNAGYCCNMGNACNCCNGTNAAYGAYCARCCN MGNYTNAGYACNGAYGAYAAYACNGAYTAYCARGCNAAYYTNCCNAARGARGARGARGAR GTNYTNGAYGARGARYTNTAYGARGAYAARGAYYTNGARGGNGTNGARGARCAYAARTCN ATHATHYTNCAYYTNYTNTCNCARYTNAARYTNGGNATGGAYYTNACNAARGTNGTNYTN CCNACNTTYATHYTNGARMGNMGNTCNYTNYTNGARATGTTYGCNGAYTGYATGGCNCAY CCNGARGCNTTYYTNAARATHCCNGAYATHCARGAYCCNGARGGNMGNATGYTNGCNGTN YTNGARTGGTAYYTNACNTCNTTYCAYAAYGGNMGNAARGGNACNATHGCNAARAARCCN TTYAAYCCNATHATHGGNGARACNTTYCAYTGYTCNTGGYTNAGYTAYGTNGCNGARCAR GTNTCNCAYCAYCCNCCNATHACNGCNTTYTAYTTYGARTGYCCNAGYAARAARGTNAAR ATHAAYGCNTCNATHTAYACNAARTCNAARTTYATGGGNATGTCNATHGGNGTNGCNATG GTNGGNAARGTNCAYYTNMGNYTNGAYGARTTYGAYGARGAYTAYGTNTTYAGYYTNCCN AGYGCNTAYGCNMGNTCNATHYTNACNGTNCCNTGGGTNGARYTNGGNGAYAARGTNACN YTNAGYTGYGARAARACNGGNTAYACNGCNAGYATHGTNTTYAAYACNAARCCNTTYTAY GGNGGNAARYTNCAYCAYATHACNGCNGARGCNAARAAYACNACNTCNGGNGARATHATH TGYAARGTNCARGGNCARTGGAAYGGNGTNATGGARTTYAGYTAYGCNAAYGGNGAYTCN CAYTCNGTNGAYGTNTCNGARYTNCARGTNACNMGNAARTCNGTNMGNCCNAAYGAYAAR CARGARGARCAYGARTCNMGNMGNYTNTGGCARCAYGTNTCNAAYGCNYTNMGNYTNAAY GAYATHAAYACNGCNACNGAYCAYAARMGNCARYTNGARGARGTNCARMGNGARMGNGAR MGNCAYMGNAARGCNAAYAAYATHCCNTAYATHGGNAARTTYTTYGAYAAYGTNGARGAY ACNTGGATHCAYAARAAYTTYCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYGAYCCNAAYATHTAYGAYMGNCAY TAYTGGGTNCCNTGGACNTCNTAYTAYTTYCAYGCNGCNTTYGCNTCNTCNTTYGCNTTY ATHTTYTTYAAYATHAARAARYTNTTYTGYTCNMGNGCNATHAARTTYCARAGYAGYGGN TTYTTYYTNGARYTNCCNGTNGTNATHYTNACNGGNYTNYTNTCNATGCCNYTNGGNATH YTNCARTTYATHCCNGCNTAYCAYTCNYTNCAYGAYACNYTNGGNATHCAYACNGARGTN TGYGTNYTNYTNTAYYTNGCNGTNTTYGCNATHATHGTNTGGAAYGCNGAYMGNMGNCCN YTNGARYTNGCNMGNCAYAARGGNAGYGGNATGTTYAGYYTNATGTTYYTNGCNGTNATH ATHCAYTAYGCNYTNTAYATHTAYYTNGTNTTYACNACNAAYCCNACNAARATHMGNTCN ACNGGNYTNCAYCARCCNGTNGGNCCNTGYAAYAARCARGTNAARGTNCARACNCCNYTN GGNCAYGTNYTNAARAARACNCAYTAYYTNTGYYTNAARAAYTAYTCNGARGAYTAYTTY ACNYTNGAYTGYYTNAARAARCCNCCNGCNGAYAARACNGARTGGTAYACNATHTGYGGN ACNGCNTAYCCNAAYCAYAARGARTAYATGGTNATHATHTGYGCNTTYTGYGCNATHGGN YTNTTYTGGTTYATHCARGCNTTYTAYMGNTCNGGNAAYCARCCNMGNATHGARTCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CCNTTYTAYMGNGARGTNCARAGYTTYGTNCCNGGNATHGCNYTNATHGTNGCNTTY ATHATGYTNYTNACNYTNATHCCNCARACNATHGGNCAYMGNAARAAYAARCCNMGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AGYMGNTCNMGNTCNAAY TCNMGNTCNAARTCNMGNTCNMGNTCNGCNTCNCCNAARAARMGN---------AGYAAY MGNTCNMGN---TCNMGNTCNMGNGAYMGNGAYMGNMGNMGNAARMGNGAYMGNAARCAY MGNTCNAAYMGNTCNMGNTCNAARGARMGNMGNMGNTCNMGNGAYAAR------TAYMGN CAYAARAARGAYMGNAARMGNAGYMGNAGYMGNAGYMGNGAYMGNMGNGAYAARAARTAY GAYMGNAARAGY---AGYMGNGARACNMGNMGNMGNAGYMGNAGYMGNAGYMGNAGYAAR ---------MGNAGYMGNAGYMGNGAYAARAGYMGNMGNCARAGYACNMGNAGYCCNAGY CCNCAYAAR------GTNATHAARTTYGGNGAYAARGTNATHAARCCNGGNGCNAGYTTY GGNMGNCCNACNACNAGYTCN------TCNAARCCNGTNACNTTYAARGARAARATGMGN CARGARYTNATHAARGCNATHGCNGAYGGNGCNGAYGARAGYGAYATHYTNGCNAAY--- AARGGNTCNACNATHTGYACNCARTCNGCNGGN---GTNCARCAR------GCNYTNAAR TCNAARCCNGCNCCNYTNCCNYTNATGGAYAARATHYTNACNTGYACNGGNGAYATHCCN CCNATGACNGTNACNGCNTCNGARGCNGTNATGCARTCNATGYTNGCNYTNCARAARGAR ACNACNGARAARACNGGNATHGARATHCCNAARTAYTAYAAYCCNGCNGCNATHAAYCCN ATGAARTAYGCNGARCARGTNCARAARMGNAARYTNYTNTGGTCNAARGCNAARGAYAAR GAYGTNAAYTCNCARTGGCAYGCNACNAGYYTNTCNGGNGAYGCNGAYGAYAARTCNAAR GARAARTTYMGNAARYTNATGGGNATHAAR---------------GCNGGNGGNAGYGGN TCN---------GGNGARGARCARGARGARAARCARAARCARYTNTTYGAYCARYTNAAY AARGARTAYGARTTYGCNMGNATGACNACNCAYACNCAYMGNGGNYTNGGNYTNGGNTTY GGNTCNGTNGGNTTYCAR---------------------CCNATHCCNGARGAY---CAR GAYAARCCNCCNAAYTGYGAYGAY------------TCNAAYTTYACNACNCCNTCNCAR YTNAAYTTYAAYACNAAYTTYTCNAGYGAYGARGAYGAYGAYCARTTYCCNGAR------ AAYGAYGGNTAYGTNYTNYTNCCNCARGARCCNGAYGAYGTNGTNGGNGARGARGARGGN GARAAYAGYTCNYTNCCNGARAGYGARAGYACNGARACNCARTTYAAYTCNCARGGNATH GAYGARGGNATHCARGGNCCNGCNGGNTCNGCNTTYCAYGAYYTNCCNGAYGARGTNATH MGNGCNGARGGNGGNACNTCNATHCCNACNGTNTGYTCNYTNAARNNNTCNYTNCAYCCN GARTTYYTNGTNAARTTYCCNGAYGGNAARATHCCNACNTAYATGCARGTNCCNGAYGTN CARACNAAYMGNAARGAYATHYTNTGGAAYAARMGNMGNATGGARCARGAY------AAY YTNGAYTCNGTNCARGARTCNAARATHGTNACNGCNATGGCNAGYTTYTCNYTNCCNTCN GARAAYGTNCCNGAYTGGGCNMGNCARATGTCNGAYGAYCARTGGAGYAAYGTNATHGCN AAYCARYTNACNCCNTCNCARAAYCARCAYCAYCARTCNAGYAAYTCNACNGAYGARAAR GGNACNAGYGAYAAYTGGGTNGCNGARTTYCCNGAY------------------------ ---------------------------------------------------------TCN ACNAAYACNGCNYTNGAY------------------------------------------ ------------------------------------------------AARYTNAARACN TCNYTNTCNAARAARGAY---AARACNTGGGARTAYGTNGCNAGYGAYACNYTNGGNACN ACNACN---TAYAARGARCARTAYGTNTTYTTYTAYAARACNTCNACNGTNGGNYTNGGN AARACNAARCARGTNATHAAYTCN---AAR------TAYGARMGNCCNCCNYTNGCNGTN GARTTYTCNGAYGTNTCNAARACNGAYTCN---------AARTTYGTNYTNYTNGGNATH CAYACNAARCCNGAYAAYACNCCNGAYGARYTNGAYGARYTNGCNAARACNATHGARTCN GTNGCNTAYGAYTTYTCNACNGAYYTNGGNGTNGTNGCNYTNGGNGAYATGAAYGCNGAY TGYGGNTAYATGAAYGGNAARGARMGNAARGCNGCNACNATHTTYAAR---GGNGGNGAY TTYACNAGYYTNYTNGGNGAYGAYGCNGAYACNACNGTNTCNCARAARACNGAYTGYGCN TAYGAYMGNGCNATHGTNTAYGGNAAYGTNYTNGAYGCNMGNAAYGCNGCNGTNTTYGAY TTYATGAARGCNTAYGAYATGACNYTNAARGAYGCNYTNGTNGTNAGYGAYCAYTTYCCN ATHGARTTYTCNYTNTAYMGNTTYAGYATHAAYYTNTGYATGGGNCCNACNTAYGAYAAY GGNTGYGCNYTNCAYTTYAAYGTNMGNTTYGAYGARGGNMGNGTNGTNMGNACNCAYATG CARGAYGGNAAYTGGGGNACNGARGARACNGCNGGNGGNTTYCCNTTYAARMGNGGNCAY GTNTTYGARGTNCAYATGCARGCNCAYCAYCAYGGNTAYAARATHYTNGTNAAYAAYMGN CAYTTYTGYGAYTTYAAYCAYMGNYTNCCNAARGARAAYATHTCNTAYATHTAYYTNGAR GGNGARGTNYTNATHCAYAAYATHCARTTYMGNGGNAAYCAYGGN---------CAYGGN GGNMGNGGNGGNGGNGGNTAYCCNCCNTCNGGNGGNGCNTAYCCN--------------- CCNTCNGGNGGNTCNTAYCCNCCNTCN------------------------------GGN GGNTCNTAYGGNCCNGTNTAYAAYCCNCCNGTNCCNTTYACNACNCCNATHCARGGNGGN GTNGTNCCNGGNAARATHATHTAYATHTCNGGNGTNCCNAAYCCNAAYCCNAGYMGNTTY ACNGTNAAYYTNCARTGYGGNCCNTAYGAYTCNGGNGAYYTNGCNATGCAYTGYGAYGTN MGNTTYAAYTTYGGNAAYTTYTAYAAYCARATHGTNMGNACNCAYMGNCARGCNGGNAAY TAYGGNAAYGARGARACNGCNYTNGCNCARTTYCCNTTYTAYCCNAAYACNCCNTTYGAR ATGATGATHYTNATHGARCCNACNTCNTTYAARATHGCNGTNAAYAGYCARCAYYTNYTN GARTTYCAYCAYMGNATHCAYCCNTTYAAYMGNGCNGAYCAYGTNAAYATHTCNGGNGAY GTNMGNYTNACNCARGTNMGNTTYCARACNCCNACNTTYGTNCCNAAYTTYYTNATH--- GGNGCNACNGGNYTNACNCCNACNYTNACNCCNACNACNYTNGCNACNATHGARCARTCN TTYATGGAYATHCARCAYCARGGNGCNMGNGAYCCNACNACNCARAGYGGNTTYGTNCCN CCNGTNGTNGARCCNTCNAAYAGYAAYAGYGCNGAYCAYTCNCARGAYAGYTTYGARAAY TCNTCNTCNGAYCCNGARTGGGARCCN--------------------------------- ------------------------------------------------------------ ---------------------------CCNGAYAGYTAYYTNACNGARCCNGARCAYGAR TCNGARYTNGARCARAARMGNAARGTNGGNGARCARMGNYTNCARGGNTGGYTNCARAAR GCNAGYAAR---YTNAARGCNMGNAARGARATHAARAGYCARCCNACNGCNTCNAAYYTN AARATHACNGAYTAYATHACNCARYTNCARCAYAGYYTNTCNATHYTNTCNCARYTNACN AAYCARGTNAAYAARATGGARGTNATGGTNCCNGAYGCNGAYMGNYTNAGYTGGCARCAR GARAAYAGYACNGTNGARCARYTNAARGCNMGNTAYACNGAYYTNMGNGTN---ACNAAY AARGARAARGTNAARGAYATGCARGAYAARYTNTGYAARGTNAARAAYAARMGNAGYMGN YTNAARMGNGCNGTNCARTTYAARGTNACNGARAARCARGARGCNGARMGNGAYMGNAAR GTNAARGARAARGARATHGAYGAYTGGCARAAYAARYTNGTNAAYGAYATGAARGARGAR AAYYTNAARAARAARMGNAARCARGARATGGAYCARTCNYTNAGYGARATHACNAARAAR ATHAAYGAYGCNAAYYTNYTNATHGARACNATGACNGCNYTNGARAARYTNMGNYTNATH MGNCARGAYGCNGCNATGAARMGNGGNGAYGTNGARYTNGGNGARCCNMGNAAYAGYTTY GARCARAARATHTCNGAYATGACNMGNYTNGTNMGNGGNCARYTNGARGTNTAYAARGAR GARGARGARAGYATHMGNAARGCNATHCARTCNGARCARGAYGCNACNAGYGARAARGAR AARATGYTNCARCARCARCARGARATGGARYTNCARMGNCARAARGGNGTNGAYYTNTAY MGNAARYTNTTYGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYYTNGTNTTYYTNTTYGGNCCNCCNYTNCAYGAYAARGCNAGY TAYYTNTCNCCNTCNYTNTTYMGNCARAAYAARYTNAAYATHMGNTGYATHTTYGARGAR MGNCCNGCNYTNGGNYTNMGNGAYATHTCNYTNCARATHGTNGCNGAYYTNMGNAARAAY AARCARGTNTTYATHGARGAYGARTTYAAYTCNTCNAAYACNMGNAARAGYATHYTNACN ACNGTNTTYAARAARGTNCCNAGYTGYAARGCNYTNYTNGTNAAYATHATHCCNAARCAY GGNYTNYTNCARGTNYTNTGGAAYCAYCARTTYGCNCAYGGNMGNGGNTGYYTNCCNAAR TGYTCNTGYCARCAYATHAAYTCNATHGCNAARCAYTGGTTY------------------ ATHGAYAAYMGNTCNAAYTAYGTNGAYACNCCNAARAARGARGARGGNTAYGAYATHTCN GARYTNAAYGTNCARYTNACNATHCCNTCNTAYTCNAARTTYAAYGTNCCNGCNYTNTTY ATHGARTGGGARGCNGCNATHTCNGARACNGGNAGYYTNCAYYTNGCNYTNTGYAARATH TGYCARCARTGGATHGCNCARAAYGARAAYGGNMGNATHATHYTNATHTGGGAYGGNAAR AARGCNYTNAARGAYGGNGAYYTN---------GARATHAARMGNATHTAYCARGAYYTN AARTCNYTNTCNATHAARYTNCAYCARCCNATHTTYYTNYTNMGNYTNTCNAARGGNCAY GTNAAYAGYTTYTGYGCNCCNCCNCARCCNGGNATGYTNGCNTTYYTNCARTCNCARCAY GGNATHGAYYTNCARTCNAARCAYACNGTNTAYATHYTNGARACNTCNGARCAYYTNAAR ATGGCNYTNGCNGCNGGNGTNAARTCNGTNAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GCNATHTTYMGNAARGGNMGNTGYGGNTTYCCNMGNTCNYTNTGGGGNYTNAAR CAYAAYGTNMGNTGYGCNTCNGGNGTNAAYTCNCAYTAYGTNYTNYTNCCNGARGTNCCN CCNGAYACNGCNGARTCNAAYGCNGTNATGMGNATHGAYCARYTNCCNCARTTYTCNAAR ATHTCNCCNTAYACNTGYYTNACNGGNTGYGCNAARYTNACNATHGARTAYGARACNAAR TTYGARAARCAYATHACNAGYYTNAAYGAYCCNAARAAYGARAARAGYTTYGAYGAYGTN TAYYTNCCNATHGARGARATHTCNGTNCCNYTNAAYACNGCNTGGGCNACNYTNAARAAY YTNCAYTAYGAR------AGYGAYGAYTAYMGNMGNGCNTTYTCNAARGTNCAYCCNCAR GTNGARMGNGTNAARAAYGAYMGNTGGATHAGYCARACNYTNTAYTAYGCNTTYAARGAR YTNGARGCNAAYAGYGCNAAYYTNACNGARTAYCARAARMGNYTNGTNGGNYTNTAYYTN YTNGARGGNAARYTNAAYGGNGTNCAYYTNTCNACNGARGARAAYTCNAARYTNGTNGAY CAYYTNAARYTNATHGCNAARGARAGYCARAAYTTYMGNAAYAARGTNMGNATHTGYACN GAYGTNTTYTCNCAYGAYGTNTCNGAYTTYAAYTCNATHGARGARATGCCNTGGCCNYTN YTNGCNCARATGTCNYTNGAYMGNTCNGAYCCNACNMGNGGNCCNTGGMGNGCNACNYTN CARCCNAAYGTNTAYCARGCNATGATGTCNTAYTGYAGYCAYMGNYTNACNMGNTGGAAY YTNTGGAAYGCNTAYCAYAAYMGNGCNTCNCAYAAYCAYGCNAGYCARTAYYTNAAYAAY AAYAARYTNATHGARAGYYTNMGNGCNTAYMGNCAYGAYGTNGCNGARATGYTNGGNTAY AAYCAYTAYGCNGAYATGTCNATGGARACNAARATGGCNGGNTCNGTNGARAAYGTNATG GGNATGATHGARACNYTNMGNTCNMGNTTYGCNCCNGCNGCNTGGGARGARGTNGCNCAR YTNCARCARTTYGCNTCNTCNGARGGNTTYAARCAYAAYYTNGARATGTGGGAYATHGGN TAYTGGMGNMGNMGNCAYMGNGARCAYYTNTAYAGYGTNAAYAARGAYGARATHAARCAR TAYTTYCCNATHAAYTCNGTNYTNYTNGGNYTNTTYGAYYTNTGYACNAAYYTNTTYGGN GTNAAYTTYGARGARGTNTCNCCNGARGTNGARACNTGGCAYTCNGAYGTNMGNTTYTTY AAYGTNYTNGAYGGN---GAYGGNAARCAYATHAGYTCNTTYTAYTTYGAYCCNTTYGAY MGNCCNGGNAARACNTCNTCNGGNTAYATGGAYYTNGGNMGNGAYAAYAGYGARCCNTGY GGNACNTGGCCNTAYTCNTAYYTNTGYYTNAARATHCCNMGNCCNGCNTCNTCNACNGAY CCNGTNYTNATGMGNTTYGARGAYATHGARATGYTNTTYTCNGARTTYGGNCAYGGNYTN CARCARATGYTNACNCARGTNCCNTAYAGYGARATHTCNGGNCARAARAAYATHGARTGG GAYTCNGTNCAYGTNTGYGCNAARTTYATGAARCARTGGYTNACNATHCCNTCNYTNATH CARGGNYTNAGYAGYCAYCAYCARACNGGNGARAARATHCCNGGNGAYATGGTNAAYCAR ATGYTNAARGCNTCNCARCAYTGGAGYAAYTTYGAYATGATGTAYCARYTNTAYGTNTCN GCNTTYGAYYTNGARGTNTAYATGACNAARACNCAYTAYCAYTCNGTNATGAARCARYTN TGGGARAAYTTYATHCCNYTNCCNYTNAGYGARGAYGAYCARYTNCCNTGYTCNATGATH CCNATHTTYTGYGAYYTNTAYCCNGCNGCNTAYTAYTCNCAYAARTGGTCNGARATGATH GCNACNGAYATHTTYTCNGCNTTYAARGARGCNGGNATGGAYGAYCARGARAARATGAAR GCNYTNGGNMGNMGNTTYMGNGAYACNTAYYTNTCNCARGGNGGNGGNATGMGNTCNTGY GAYGTNTTYMGNCARTTYMGNGGNMGNGAYCCNACNACNAARTCNYTNCARCCNATGGAR AAYAAYAAYGCNATHGCNGCNAAR---CCNGARGAYGGNGARTCNAARATHGARGAYGTN AARCCNACNGTNGAR------GAYGAYTCNTCNCCNAAYAAYMGNAAYMGNGGNMGNMGN MGNCCNCCNGTNMGNMGNGAYGTNAAYCCNGARGAYGARACNGGNAARGCNGCNATHMGN MGNAARATHTGGGAYCAYTTYGARGAYGARAAYYTNGTNAAYGCNCCNMGNCCNTGYCAY TAYMGNATHCCNAAYTTYGARGGNGCNTCNGARGCNGCNGAYAARYTNACNAGYYTNGAY GCNTTYAARAAYGCNAAYACNATHAARGTNAAYTCNGAYAARGCNCARGARCARGTNMGN TTYYTNGTNYTNGARGCNGGNAARGARYTNGTNYTNYTNAAYCARAAYGARAARGAYYTN ATGGTNCCNACNCCNGARYTNAARTGYGGNYTNYTNAAYMGNGTNGTNGCNCCNGARGGN TCNAAYAGYGARGARYTNAARCAYTGYTGYACNACNCARGGNGTNAARGARAAYAGYAAR GARATHGGNYTNGARGARAARGTNAARYTNGAYGTNATHTTYGTNGGNAGYGTNGCNGTN TCNMGNAAYGGNTCNMGNATHGGNAARGGNAARGGNTAYGCNGAYYTNGARTAYGCNATG ATGMGNACNATGGGNGCNGCNAAYGCNAAYACNGTNGTNATHACNTCNGTNCAYGAYTCN CARGTNGTNGAYATHGCNGAYGAYYTNGTNGGNGARCAYGAYATHACNGTNGAYTAYATH YTNACNCCNACNGARGTNATHGARACNAAYAGYAARMGNCCNMGNCCNTCNGGNGTNACN TGGAAYCAYYTNGARGTNAAYAARTTYTAYCARGTNCCNGTNYTNMGNCARYTNMGNAAR AAYGARAARGAYGAYGGNAARGAYGTNTTYYTNAARGAYCARAARGARGARGAYGARGAY CCNGTNGAYACNATGGARCCNCCNMGNCCNMGNMGNTTYGTNMGNAAYTAYMGNAAYGCN GGNGGNTAYMGNGGNMGNGGNMGNTCNTAYGGNMGN---TAYMGNMGNGGNGGNAGYMGN MGNMGNCAR------TAYGGNGAYGAY------AARGARAAYCARGAYGGNGGNGARGAY TCNGGNGCNGAYGGNGAYAAYGARGGNMGNCCNAAYMGNMGNAGY--------------- AGYTAYMGNAAYMGNMGNTAYMGNMGNGGNGGNGGNGGNMGNCCN---MGNGCNTCNGAR TCNGARCAYAGYGAYGGNGCNGGNGARATHMGNGARGGNGAYGGNGAYGAYAARCCNMGN CARMGNGGNTAYAAY---AAYMGNMGNMGNTAYAAYAAYAAY---CCNMGNMGNTAYAAY CARGAYGAYMGNMGNGAYAAYMGNGAYAAYMGNMGNGAYAAYGAYCARTCNGGNAGYGAY GGNGARCAYAARAAYTCNGCNGAYGARGAYGGNGARGGNMGNMGNCARMGNMGNAAYMGN GTNCCNACNAAYCCNGAYGCNGTNGTNTGGYTNGGNGCNYTNCCNAARAGYYTNMGNGTN AGYGTNYTNAARGARGTNYTNAARAARCAYGAYGCNATGCCNATHMGNYTNYTNTGGMGN GGNGGNCAYGGNTTYGCNTTYYTNTTYTTYATGGARGTNGARAAYGCNAARGAYGCNGTN AARAAYYTNACNGGNGTNGARGTNYTNGGNMGNGARATHAARGTNGARATGGGNAAYTCN GAYMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATGAGYCAYGTNGARGAYMGNTCNGGNMGNAGYYTN TTYYTNCAYAARCAYGAR---------GAYYTNTAYTAYTCNCCNCARTTYAGYAARCAR GCNATHGARGARATGCCNGAYTTYAARTTYMGNAARGAYGAYGTNGTNYTNATHAGYTAY CCNAARTCNGGNTGYCAYTGGGCNTGGGARATHYTNMGNATHYTNGTNACNGGNGAYGAR AAYAARGAYCAYGTNGAYAARGARGARTAYATGYTNGARTGGMGN---GTNGGNGCNGAR ATHGCNGCNATGCCNTCNCCNMGNGTNYTNAAYAAYCAYATGCCNTTYGCNMGNCARCCN AARGAYYTNYTNGTNACNAARCCNAARATHGTNTTYTTYTAYMGNAAYYTNAARGAYGTN GCNGTNTCNTTYTTYCAYCAYCAYTGYGGNATHCCNGCNTAYGGNTAYMGNGGNGAYAAY TTYGARGCNTAYGTNCAYMGNYTNATH--------------------------------- ------------------------------------------------------------ ------------------GAYGGNYTNGTNGARTGYGGNAAYCCNTGYAARTAYTAYMGN GARTGGGAYGARGGNATGMGNAAYCAYCCNGARYTNTCNGTNTAYTGYTGYAGYTAYGAR GAYATGAARCARGAYCCNATGTCNGARATGMGNAARGTNTGYGARTTYYTNGGNAARAGY TAYGAYGAYACNTTYYTNCARAGYGCNTGYGCNAARACNAGYTTYAAYTTYATGAARGAR ACN---------------AARGGNAARGCNYTNCCNYTNTTYTAYMGNAARGGNCARGTN GGNGAYTGGAARAAYCAYTTYACNGTNGCNYTNAAYGARTGGTAYGAYGAYGTNATHMGN AARGARATGCCNGAYGTNMGNTTYAAYTTYMGNTAYACNYTNYTNATHGGNTAYGGNATH GGNMGNTTYTCNTCNTGYCCNATHGCNMGNTAYCARYTNGCNTAYYTNYTNYTNYTNCAR GARAARYTNCARACNGAYCCNCCNYTNYTNTAYGAYCCNGTNTTYTCNYTNGARCARAAR AARTTYYTNGARGARATGGGNTGYGARYTNATHCCNCAYAAYGARGARGGNAARCAYYTN TGYACNGTNTCNACNATHYTNTTYATGCCNCAYTGYGGNAARGCNYTNTAYAAYAAYYTN ATHTGG------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TGGTAYAAYAAYYTNTCNGCNGAYCCNGAYGAYTTYAGY YTNCAYATH---GGNACNGAYMGNAGYGGNGTNAARGARTAYYTNCAYAARGARGGNYTN GTNATHGCNAARGCNAARTCNTTYYTNCARAARCARMGNMGNACNYTNAARCARMGNCAR TCNACNYTNGCNGCNGCNAARCARGARYTNAAYAARGAYACNAGYATHYTNYTNCARTCN AAYCCNACNAAYGARGCNACNGARATGYTNGARAARGTNAARGAYACNYTNGARTCNGAR GTNGTNGARATHGAYGCNYTNCARTCNAARTAYGAYTCNGARTCNAARYTNYTNAARGAR AARGARGARCAYTAYCAYMGNYTNGARGGNYTNACNAARGARAAYGAYAGYGAYGAYGAR TCNGARTAYAGYCCNTTYGGNMGNCCNTTYCAYCAYGTNAARATHCCNAAYATGGAYYTN AGYGARGAYGARAGYAGYGGNATHAGYAGYTCNGAYGCNAGYYTNGAYGGNTTYTTYCAY ------CAYMGNCAYGTNGGNTCNCAYACNCCNGGNGGNGCNTTY------------GGN GARGAYYTNTCNAARGCNYTNTAYMGNATHAAYCAYGAYYTNTCNCAYGTNYTNAGYGTN ATHGGNAARGAYGGNGARTCNGTNYTNGGNTCNAAYATGCCNMGNCCNCCNTCNACNCAY CAYTAYCAYGGNATGCCNGARGGNATGCARTGGATGCCNCAYCCNCCNAGYCAYCCNCCN TCNAARGAYTAYTCNACNYTNGTNGCNACNGCNGARCARTCNYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GAYYTNTGYGCNGTNTGYYTNGAY AAYTTYCAYATHAAYCARAARYTNMGNATHYTNCCNTGYTCNCAYTTYTAYCAYACNMGN TGYGTNGAYCCNTGGYTNGTNCAYAAYMGNACNTGYCCNYTNTGYAARYTNAAYATHYTN TCNACNCARACNGARGCNGARTTYGCNATGAGYATHAARACNGCNTTYACNTTYAAYGAR YTNACNGARGCNACNGARAAYTTYAAYGAYACNAAYATHYTNGGNGARGGNGGNTTYGGN GTNGTNTAYTAYGGNAARYTNMGNAAYYTNGAYTGYGCNGTNAARAARTTYAARMGNAAR GCNGARAAYGGNAARGAYTCNACNGARCARATHAAYAGYGARYTNACNGCNYTNYTNAAR TAYCARCAYGARAAYATHGTNACNYTNTAYGGNTAYGCNYTNGAYGGNCCNGAYYTNTGY YTNGTNTAYCARTAYYTNTCNAAYGGNTCNYTNGARGAYMGNYTNATGMGNAARAAYAAY ACNGCNCCNYTNTCNTGGGARMGNMGNYTNAAYATHYTNGTNGGNTCNTGYAARGCNATH AGYTTYYTNCAYACNATGGGNTCNACNCCNYTNATHCAYGGNGAYGTNAARAGYGCNAAY ATHYTNYTNGAYCARCAYYTNGARGCNAARTTYGCNGAYYTNGGNCARTCNMGNTAYGCN AAYAGYMGNACNGCNAAYACNGGNAGYTTYACNCAYATHACNYTNGCNGARACNAAYACN MGNCARTAYGGNACNATGCCNTAYYTNGCNCCNGARGTNAARAARGGNTCNMGNYTNTCN ------ATHCARTCNGAYATHTAYGCNATGGGNGTNGTNATGYTNGARGTNGCNAGYGGN YTNGCNGCNTAYGAY---AAYGARAAYCARAAYAARYTNYTNACNGAYTAYTAYACNMGN CARATHGCNACN---TTYGAYGARTCNGARCARGTNMGNATGTTYAARGAYCARAAYCCN GARGAYGAYATHACNTCNACNACNTTYATGTCNYTNYTNAARGCNGCNAGYTTYTGYYTN AARGARATHATHAARAGYMGNCCNTCNAGYGCNAARYTNYTNAARAARACNACNGAYATH TAY--------------------------------------------------------- ---------YTNCARYTNGGNAARGGNACNAAYYTNYTNGGNGCNATHAGYATHGCNAAR AAYYTNYTNAARGARAGY------YTNAAYGGNACNTCNYTNGARGAYMGNATGTGYGCN GARCARTGGYTNGARTTY------------AGYCARGARATHACNAAYATHGARAARAAY GGNGAYAARGARMGNATGAAYGTNATHYTNAARGAYYTNAAYTCNCAYATHAARGARCAY GTNTAYTTYATHGGNCARGARTGYACNGTNGCNGAYATHTTYYTNTAYCAYAGYYTNCAY CCNGTNTTYGARAARYTNACNTTYCARGARAARGARAARTTYATHCAYYTNTCNMGNTGG TTYTCNCAYATHCARGTNGAYGAYAARACNMGNCARTCNYTNCARTCNYTNAARTTYYTN MGNACNATGYTNTAYACNGGNGTNACNAAYCAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGGAYYTNYTNMGNTCNTGG YTNTAYGGNMGN------GARAAYACNAAYAARTTYTCNGGNGGNGAYAAYCCNAARTCN ACNAAYGAYCARYTNCARGARMGNYTNCARGARAARGARCAYCCNTCNGTNATHGARAAR TGGATGYTNAARATHGTNCCNYTNCARCCNGGNGAYTGYYTNGGNTGYAARYTNGTNGGN ACNTCNGTNTTYATHACNAGYGGNGTNATHGTNYTNACNTCNGCNGTNGCNGGNMGNAAR MGN--------------------------------------------------------- ------------------------------------------------------YTNNNN NNNAAYACNACNAARACNGTNAGYACNYTNTTYCAYYTNGAYAAYCAYAARGCNNNNCAR CARYTNNNNNNNNNNNNNAANAAYTCNNNNYTNCCNTAYGAYNNNAAYCCNAARTAYYTN GGNGTNATHYTNGAYMGNNNNYTNNNNTAYNNNNNNCAYYTNGARAAYACNGCNAAYAAR YTNNNNAARMGNAAYGGNATHNNNMGNAARNNNNNNGGNACNTCNTGGGGNGCNNNNNNN NNNGTNYTNMGNACNTCNTCNNNNGCNYTNNNNTAYAGYGTNGCNGARTAYTGYGCNCCN GTNTGG------NNNMGNTCNNNNCAYACNNNNNNNGTNGAYACNNNNYTNAAYNNNACN ATGMGNACNATHTCNGGNACNYTNAARTCNACNCCNACNNNNTGGYTNCCNNNNATGAGY GCNATHGCNCCNNNNNNNYTNMGNMGNGARGARGCNACNCAR---AARCARCAYMGNMGN YTNGARAAYATHACNTCNAAYACNCCNYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARACNCCNGGNTTY GARGARGAYAARGAYTGYYTNTTYGAYMGNATHTCNGAYAGYTAYGTNGCNYTNTTYACN AGYATHAAYACNGAYGTNAARGAYAARTTYYTNTCNGTNTAYCCNAGYTGYYTNTCNCAR GCNYTNTAYTAYACNTAYYTNGARGCNTTYCCNGARTCNAARTGGAARTTYGAYGARAGY TAYAARCARTAYYTNGTNAAYYTNGTNTAYGARTGGGTNACNGGNYTNMGNCCNGTNCCN GGNGTNTGGAARGCNTGGATHGARGARGGNYTNGARGGNAGYCAYACNGGNMGNGARACN GARACNGCNAARAARATGYTNGARGCNGCNGCNYTNAAYAARAARGTNGARATHAGYYTN GAYATGGAYTCNTTYGCNAARGTNATHGAYAARYTNGGNTCNGAYTCNGARGCNAAYYTN CARGGNCAYATGTCNMGNGARGTNACNAARACNTCNAAYMGN------ATH------CCN TCNMGNGGNMGN---------YTNAAYCARGARTCNCAYCARATHGGNCCNGGNCCNGAY TAYGARMGNGTNAARTTYAAYACNTCNGGNMGNAGYCCNYTNATHTCNCAYTAYYTNCAY ATGMGNCARYTNMGNAGYTAYAARCARCCNGGNATGAARGTNMGNMGNACNGARATHYTN AARYTNCCNCCNGAYGGNCCNACNTAYCARCARTTYATHGCNGAYACNYTNAAYAARGCN GARTCNYTNGARAARGARTAYACNMGNATHTGYGAYCARACNTCNTCNGCNATHYTNGAR YTNGARAARTAYAARMGNGAYTCNAAYAARGARATHGGNGARATGAARAARGCNYTNACN AAYATHAARACNATHCCNGARMGNMGNYTNYTNATGGAYAARATHTCNGARTAYAARGAY YTNGTNATHAARGARMGNCCNYTNTTYGARACNTCNATHTCNCARACNGAYGTNAARTCN TCNACNTCNTAYTCNTCNGAYGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TAYTAYMGNYTN CCNAAYCCNGCNYTNGCNACNTTYATHATHYTNYTNATGYTNTAYYTNYTNGTNGTNACN GTNTCNCCNCARAGYYTNCCNGCNTTYYTNGGNCCNATHACNCARTTYGGNCARTAYATG GCNTCNAARCARTTYAAYTTYGTNATHGCNGCNTGYTAYTTYYTNGTNATHGCNCAYAGY YTNGARGCNGCNTAYGCNGGNAARGTNTGYAGYGAYMGNGGNTAYGCNGTNTCNACNACN ATHAARTGGGTNGTNTCNGTNTTYYTNYTNGGNTTYCCNTCNATGATHMGNYTNYTNCCN CAYAARCCNGARYTNAAR---------------------------------CAYTGYGAR ATGACNAARGGNTGGYTNGARCCNYTNYTNTCNGTNATGTAYTCNAAYCCNCAYACNYTN GCNGTNCCNATGATGGAYATHATHAAYCARGAYTCNTTYYTNTAYGARACNTCNTCNYTN GTNMGNGGNGGNTTYAGYTGGGGNATGCAYTAYCARTGGGARCCNYTNTCNAARGARMGN GTNAARGARATHGARAARTCNCCNGAYCCNTAYGARACNCCNACNATGGCNGGNGGNYTN TTYGCNATHAAYMGNAAYTAYTTYTAYGARYTNGGNGARTAYGAYAARGGNATGGARGTN TGGGGNGGNGARAAYYTNGARYTNTCNTTYMGNACNTGGCARTGYGGNGGNMGNATHGTN ATHGTNCCNTGYTCNMGNATHGGNCAYATHTTYMGNAARMGNMGNCCNTAYGGNTCNCAY GTNCCNAAYAGYTTYACNAARAAYACNYTNMGNYTNGTNAAYGTNTGGYTNGAYAAYTAY AARAARTAYTAYYTNCAYATHAAYCCNAARGCNAARGAYGTNGARTAYGGNGAYATHAGY GARMGNAARGCNYTNMGNAARMGNYTNAAYTGYAARACNTTYACNTAYTAYYTNACNAAY GTNTAYCCNGARATGATHAAYAARTTYCCNGAYYTNACNCARCCNYTNGAYAARGAYACN GGNAGYATHAARAAYYTNYTNCCNGARMGNGTNCCNATGMGNGCNAARGGNYTNYTNAAR CAYAARGGNTCNGGNYTNTGYGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CARYTNCARMGNGARGTNACNCARTCNGAYYTNTCNAARCCNACNAARAARAGYCARATH GCNGCNCARYTNAAYACNACNTAYMGNGGNGCNGTNMGNGCNYTNCARACNTTYGTNAAY CARYTNCCNTAYCARGAYYTNCARYTNGGNYTNCCNTTYACNTAYAAYGARYTNGCNYTN YTNYTNMGNCARYTNACNACNATGATGACNYTNGTNCARCARGGN---------GAYGGN AAYGGNGAYGTNYTNACNYTNYTNGAYCARGTNGAYGGNYTNAAYTCNAARTGGTGYTCN ATGGCNYTNCARCCNAAYAARGGNATHTAYTGYACNCAY---------------AARMGN GCNTGGGTNAGYGAYACNAARGTNGAYGCNAAYYTNYTNTCN---------AARAAYTTY CCNCCNACNACNGCNAARAARYTNGTNGTNAARAARAAYACNGTNGARMGNAARMGNAAY TCNGTNATGAARGARTCNAARGARAAYMGNAAYGTNATHGAYGARGAYGTNMGNCARMGN CCNAARCCN------GCNGGNYTNGCNGGNCARAARACNTTYGGNTTYGTNTCNGTNGAY GCNAARCCNTCNTAYTCNACNAAYGCNGTNGTNAARGAYATHGAYGTNACNAARGGNTAY ATGYTNCCNCCNGAYYTNCARGCNAARMGNGARMGNGCNCARMGNGCNGTNGARYTNTCN TAYAARAAYTTYGCNGAYTCNACNCAYTCNTCNMGNTCNAAR------GTNGCNCCNACN MGNCCNAGYTCNGCNCCNTCNCCNTCNMGNAARAARGARGTNAAYTTYGAYYTNMGNGAR GAYAARAARATGTAYYTNCCNTGGATHCCNGCNGGNTGYGCNCCN------TGYAARCCN MGNCARMGNTCNYTNAGYGCNGAYMGNAGYCCNTTYTAYGTNMGNTCNYTNGARGAYCAR GAYGTNTCNTTYTCNATGTCNGARMGNGARGARGGNCAYACNGCNTGGYTNCCNMGNGAR ------CARCARTCNTAYGGNTAYMGNTCNYTNCCNACNGAYMGNCARYTNMGNTCNTGY GAYGTNTCNGAYTCNGTNGTNGAYYTNATHGARAARMGNYTNTAYMGNATGYTNAAYAAR AARGCNGCNCCNTCNGARMGNMGNTCNMGNAARGAYCARATGTAYTAYAGYAGYGAYGAR GCNYTNGAYATHACNGAYYTNACNGTNGAYAARTCNTAYGAYGCNTCNAGYYTNAAYACN ACN---------------------GCNGARGCNGCNAGYATGGTNAAYGCNCCNACNYTN GARAAYATHMGNYTNAARYTNGARGARATGGARMGNACNMGNMGNGARATHMGNCARMGN TGGGGNACNATHAARTTYGTNGAYACNCAYMGNMGNACNAAR---------------GCN CAYYTNAAYGAYTGYCCNGAYGARCCNAGYGCNATGAAYTTYAAYAARATHACNAARGAR GAYMGNAAYCCNAGYYTNAAYGAYCCNATHAAYMGNGAYTGGACNGARGARCCNGTNATH TTYACNAAYGTNAARTCNAARAARAARAAYAAYYTNTAYCAY------------------ ---------------------------YTNCCNGCNGTNCARYTNYTNGAYATHAAYCAR GCNTCNYTNGAYMGNATHYTNGARGAYMGNGAYAARYTNGCNTAYTAYCAYCARAARCAR TCNCAYCAYCCNACNGGNAARTTYAAYCCNTGGACNYTNATGGARCARATHTCNGARGAR ATHYTNAAYGAYTGYYTNMGNGARGTNTCNGARGARGTNGARAARATHAAYGARGARATH GCNAAYCARATGTAYAARTCNGARTTYATGGTNACNGGNMGNCCNTCNGARACN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGGCNTCNTCNACNACNTTYYTNGTNGCNYTN ATHGGN---------ATHGTNGGNYTN--------------------------------- ---------------------------------GTNCAYTGYCARMGNCCNGTNMGNATH GCNGAYGGNTGYCARGAYAARGTNATGGAYATHTTYTTYYTNYTNGAYTCNTCNTCNTCN ATHTAYATHAAYGAYTAYATGTCNCARCAYMGNYTNACNMGNGAYATHATHAGYMGNTTY GAYATHAGYGCNGAYAAYACNMGNGTNGGNYTNYTNACNTTYAGYGAYGARYTNGARMGN CCNGTNATHGGNYTNAAYMGNTAYAAYAAYAARAAYGARYTNYTNAAYGGNATHTCNGTN CARAAYYTNCCNTAYMGNACNGGNGTNACNAAYACNGAYATGGCNATHMGNTAYGTNMGN CARYTNACNGARTTYMGNACNGAYATHACNAARGTNATGGTNGTNATGACNGAYGGNGGN TCNMGNTCNCCNGGNGGNACNGCNMGNGARGCNGARYTNGCNMGNGARGCNGGNTTYTAY ATGTAYGCNATHGGNATHGGNCARTAYYTNGARGARMGNGARTGGMGNGCNATHGCNACN GAYCCNGAYGAYAGYTTYGTNTTYAAYATHACNTCNCCNMGNYTNYTNGARGARGTNCAR TTYTCNYTNCCNTCNMGNGCNTGYGCNYTNCCNCCNATHATHMGNGGNTCNACNTGYGAY ATHTCNMGNTCNTCNGARGTNTAYTTYGTNGGNGGNMGNAGYACNAGYTCNCARGCNGTN GAYGTNATHGGNACNTTYACNACNMGNACNACNGAYMGNMGNGAYYTNYTNMGNGCNAAY TAYYTNATHAGYGGNTGYAGYCARGTNGAYAAYATHGTNYTNGTNAAYAAYGARCCNTTY GTNTGYGARMGNTAYGAYYTNAAYACNAAYGARCCNGTNTCNACNACNAAYYTNTTYGAR GAYGCNGTNACNGCNATHMGNAAYTCNMGNAGYATHGGNCCNGAYACNCARAARGTNATH GTNYTNTTYGTNGAYGAYGTNACNYTNTCNACNGAYMGNTTYGARYTNGCNAAYYTNGTN MGNAAYGCNGARAAYTTYGAYGGNGTNACNGTNGTNYTNGCNGAYATHGGNACNMGNACN TTYMGNGAYTTYGCNCARMGNATGGTNCARACNMGNAGYAAYATHGTNAGYTTYGTNGAY GAYAAYGTNTCNACNCARTCNAAYGCNYTNAGYMGNYTNCAYMGNGCNTTYTGYGAYGGN ATGGCNGAYAGYTCNAAYCAYCCNGAYYTNYTNTTYGAYAGYCAYCCNGARGGNTCNGGN TTYTCNAAYGAYGAYTTYGARAARGTNGAYGCNCCNGGNGGNCAYCAYGAYACNGAYGTN AAYGCNGCNTCNGGNGCNTAY------------GAYCAYGAYCARGAYGCNGARATHTCN ACNACNACNGAYGTN------GCNGGNGARGARGARGCNGARGCNGAYMGNTTY------ ------ACNGAYTCNCCNGAYGTNYTNGCNCAYCAYCCNGAYCCNYTNATHTCNTGGGGN GAYGAYGAYGCNGCNTCNGAR--------------------------------------- ---ATHCARCCNTCNGCNCCNGTN------CCNGARAGYATHGAYCCNYTNGTNAGYTTY ---GAYGAYGAYTTYACNGGNCARGAYAAY---ATGCARTCNTTYAAYCCNCCNATHCCN CCNACNAGYACNACNCCNGARCCNAARTTYCCNTCNTCNACNCCNAGYCCNATHCCNTCN CARYTNATHGAYGARTTYYTNGARCCNAARAARGARGARAGYGARAGYGARAGYAARCAR GTNTCNGTNTCNGAYAARACNGCNGTNGARACNGCNGARGGNTCNTGGATHAARGGNGTN GAYCCNMGN---------------------------------GTNATHGAYYTNATHTAY TGGMGNGAYGTNAARACNACNGGNATGGTNTTYGGNGCNATGATGGTNGTNYTNYTNTCN YTNGCNATHTGYTCNYTNYTNAGYGTNATHGCNTAYYTNTCNYTNGCNGTNYTNGTNGTN ACNTTYAGYTTYACNGTNTAYAARAARATHATGAGYGCNGTNCARAARACNAAYGAYGGN CAYCCNTTYAARCARYTNATHGAYATGGAYATHGCNYTNAGYGARGAYAARYTNAARAGY GTNATHCARTCNGTNYTNAARAAYGCNAAYTGYACNGCNAGYGARYTNMGNMGNYTNTTY YTNATHGARGAYATGGTNGAYTCNATHAARTTYGGNYTNYTNYTNTGGGTNYTNACNTAY ATHGGNGCNTGGTTYAAYGGNATGACNYTNGTNATHYTNYTNGTNATHTCNATHTTYACN TTYCCNAARGTNTAYGARACNTAYAARGTNCARATHGAYAAYTAYATHGGNYTNGCNAAR GCNCAYGTNGAYAAYGTNATHAAYATHGTNCARAGYAARYTNCCNTTYYTNAARAARAAR GARAARGCNCAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNGAYYTNGARGTNAAYGTNYTNYTNGAYTTYACNMGNGGNTCNMGNGGNGAR CAYAAYTCNMGNACNATGYTNMGNCCNYTNATGAARAARTGGCCNAAYGTNAARGTNGCN YTNTAYCAYACNCCNGAYYTNMGNGGNTGGYTNAARACNYTNACNCCNGARMGNTTYAAY GARACNATHGGNYTNACNCAYATGAARGTNTAYYTNTTYGAYGAYAGYTTYATHATHAGY GGNGCNAAYYTNAGYAAYGAYTAYTTYACNAAYMGNCARGAYMGNTAYATHYTNTAYAAY GAYTGYGARAGYATGGCNGAYTTYTTYCARCAYYTNGTNAARACNGTNATGTCNTTYTCN YTNCARYTNGARYTNGAYGAYTCNYTNCAYYTNGCNCCNGAYTGGAAYATHCAYCCNTAY YTNGAYACNGAYAAYGGNGTNAAYTTYAARYTNGCNGCNMGNGARAARATHAGYCARTGY YTNMGNACNCARGARATHGTNYTNGAYGAYTAYGARGAYAAYAAYAAYTAYGTNTTYAAR GARGARTAYGCN------------------------------GAYACNGTNGTNTAYCCN YTNGTNCARATGGGNCCNTTYGGNATHCARAAYGAYGARAARGCNACNGTNGAYYTNTTY YTNMGNTCNGAYCARMGNGAYYTNATHYTNYTNACNTCNGGNTAYTTYAAYYTNACNGAY CARTAYACNGAYGTNATHYTNTGYGAYGCNGARGCNAARTTYAARATHYTNATGGCNTCN CCNAARGCNAAYGGNTTYYTNGGNGCNAARGGNGTNGCNGGNGCNATHCCNTAYGCNTAY ATHTAYYTNGCNAAYAARTTYTAYGAYAAYGTNATGAARATGGGNCARTCNCARMGNATH CARATGYTNGARTAYGARMGNGARGGNTGGACNTTYCAYAGYAARGGNYTNTGGTAYTAY ACNCAYGAYGARTCNYTNCCNMGNYTNACNYTNATHGGNTCNCCNAAYTTYGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARCCNGCNCCNTCNACNCCNAARGTN------AARAARCCNCCNAAR AARAARAARAARMGNCCNTCNCCNMGNAAYCAYYTNTCNTCNTCNAAYCAYTGYAARTCN CARCCNACNMGNCAYTAYMGNYTNAAYYTNGCNGARATHCCNTTYGTNGCNGGNCARTCN ACNACNGCNAGYCAYTCNYTNGGNGCNAAYGTNCARAARGTNYTNGCNATGATGAARTCN CAYAAYGCNGCNYTNTGYTCNCARGCNTCNCAYCARAAYGGNGTNTCNGGNCARGGNTCN GAYAGYTGYGTNTCNTCN---TCNGGNTCNACNACNTCNTCNACN---GAYCARGAYYTN ACNGARYTNYTNAAYCARYTNCARGAYGARTTYMGNCARYTNAGYAGYGAYCAYCARGAY YTNGTNCARCARYTNGAYGGNGCNGTNGAYAARATGGARMGNYTNGAYYTNGARCARGAR ATHGARGTNYTNACNTCNMGNATGGARTCNAARGCNCARCARATHGAYAARATGMGNACN CAYCAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TCNTCNGGNCARGTNTCNAGYCCNTCNTTYTCN TCNGGNCARCCNGTNGTNTCNAGYATGATHMGNGAYCCNGARCARACNACNYTNTGYTCN MGNGAYCARGARCCNACNCCNYTNYTNTCNGCNCARTAYGARACNYTNTCNGAYGAYGAY GTNATHGARACNAARCCNTCN---ACNACNCAYAAYTGYAAYGTNTAYMGNACNGTNGTN AARGTNAARGCNCCNACNAARGTNGTNGAYGAYACNYTNCCNYTNTGYCCNTTYAAYAAR TAYAARGARTGGGCNGARGAYGTNAARGAYGTNAARYTNATHGARTCNYTNGGNGAYGAY ACNATHATHTAYCARACNACNACNAAYAARATHGCNAARGTNATHTCNTCNMGNAGYTTY GTNACNATHGGNAARAARAARAARATGGCNCCNACNACNTTYTCNGTNACNGTNYTNGAR YTNATHACNGTNAAYCCNYTNMGNMGNAARNNNGTNMGNGGNGTNTAYGGNCCNTGYGGN TAYMGNATHAARCCNGAYCCNCARAAYCCNAAYCAYACNATHTGYGARATGTGYATGCAR GTNGAYTTYGCNGGNAGYATHCCNAARMGNGTNATHAAYGGNTGYATGCCNAGYACNATH GTNAGYTCNCAYGARTCNTAYATGGCNTAYATGAARAARAARGGNTAYYTNATGTGGMGN AAYCARACNYTNMGNAARGGNMGNCARATHYTNTCNYTNACNCARAARCAYYTNGCNACN GARGCNGGNAAYGCNGCN---------CCNACNCCNCCNCCNACNCCNAARMGNGGNGGN TTYGGNGTNTTYAARTTYYTNGGNYTNAGYYTNCCNYTNGCNACNGGNGGNYTNYTNGGN TAYGCNTGGTAYGAYAAYGAYTTYMGNAARCARYTNGARGAYAAYGTNCCNTAYTCNAAR GARATHYTNGARACNGTNYTNCCNCARAGYGARCCNAGYGTNCARAARAARGARCCNCCN AARCCNACNATGAARCCNGCNNNNNNNNNNNNNNNNNNNNNNAGYNNNAARGAYGANNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNAAYNNNNNNNNNNNNNNNNNNNNNNNNYTNGGN GARAAYGARACNAARAARGARGARYTNACNATGGARCARAAR------------YTNMGN AAY---AARGARYTNGARGAYAARGCNGAYAAYGCNGCNYTNGARGTNGTNATHGAYAAR YTNYTNCARTCNGGNCARAAYTGGGTNACNGARGCNGCNAARGCNCARGTNCAYGTNGCN AARGCNACNAARAAYCAYAGYTCNYTNYTNAARAARGCNATGGAYGARACNTCNAAYATH YTNCAYAARGAYTCNGARTGGGARGCNGTNACNGTNGCNTTYAARGARMGNGAYAAYACN GTNGCNMGNGCNAAYGARYTNGTNGAYGARGCNMGNAARACNATHGARAARYTNAARAAR GTNYTNGAYGARGCNAARTCNAAYAARGTNACNATGAARAAYCARGCNATHTTYACNGCN ACNAARAARYTNTCNGAYTTYAGYAARGARATGTCNGTNGCNGGNAGYCARGTNMGNCAR GCNGAYGCNGARGCNAARGTNATGYTNAARTAYAARGAYYTNGTNGAYAARGGNMGNAAR CARTTYCARGARGARYTNGAYAGYYTNYTNCCNGAYATHAARMGNGGNMGNAAYAGYMGN AARYTNAGYGARGARGARYTNAAYGCNYTNATHGCNCAYGCNCAYMGNMGNATHGARCAR YTNCARAARCARATHGCNGARCAYYTNGCNATGGARCARAARMGNYTNGCNGTNGCNYTN GAYGARCARAARAARGARAAYAARAGYYTNACNGARTCNGCNGTNGGNGAYGARMGNGCN CAYYTNTTYGCNGARTTYGARATGGARMGNCARAARATGGARATHGARTTYTCNGCNTGG ATGGARGCNGAYGTNMGNAARCARYTNGGNMGNCARGCNGCNGCNCAYAGYGAYCAYYTN MGNGAYGTNYTNGCNGTNCARGARGAYCARYTNAAYAARGAYTAYGARMGNAARATGAAY ATHAARYTNYTNGARGARMGNGARAARTTYCARACNGARACNACNGGNTGGATHTCNMGN YTNAARGGNATHGARGCNGCNGTNGAYGCNMGNGCNGCNAGYGARAARYTNGCNCAYACN GCNCARGAYYTNTGGYTNGCNTGYATHGCNYTNAAYTCNACNATHCARTTYGGN---GAY GAYACNGARGAYAARCCNATHCCNYTNCARCARCARGTNGAYACNGTNATHAARTCNGCN GAYMGNCAYCCNTTYGTNGARACNGTNGTNAARACNATHCCNCARACNGCNYTNGARMGN GGNATHTAYACNGARAAYGARYTNMGNGAYMGNTTYGTNMGNGTNTCNCARATHAGYMGN MGNYTNGGNYTNGTNGARGARTCNGAYGCNTCNYTNTAYAARTAYYTNGTNTCNTTYYTN CAYTCNTTYTTYACNGTNAGYAAYGTNGCNGCNTAYTCNGARAARGAYYTNGTNTCNYTN GAYGARATGGAYAAYTTYAARYTNGTNGCNAAYGCNCARTAYTGGATGGARAARGGNAAY YTNGAYATGGCNGTNMGNTTYATGTGYCARYTNAAYGGNCARTCNAARGTNGCNGCNGGN GAYTGGATHGCNGARGCNAARYTNYTNYTNGARACNMGNCARGCNGCNAARACNATHYTN TCNTTYGCNTCNGCNACNGGNYTNGCNGCNACNTTYGARGAYYTNAAYGTNATHGARYTN YTNTGGAARCARGAYGTNGAYYTNGGNGTNGGNAARGARGTNTAYGAYTAYACNYTNMGN GARGARYTNGARMGNAARCARGARCARGARCAYYTNAARCARGARGARCARMGNAARGCN CARAAYGCNGCNMGNGARAARGARGARMGNAGYMGNCAYYTNGARGCNAGYMGNTGGYTN AAYCARAAYTAYTCNMGNGAYGGNGARACNGGNGARTGGGTNAARMGNCARAAYAARACN GCNACNAGYAAYGARGCNGTNGGN---------GTNACNACNGAYGARAAYGGNGAYTTY YTNACNYTNGARGCNGCNYTNGAYTAY------------------------YTNYTNAAY AAYGTNAAYACNACNCARGARAGYAAYGGNGTNGTNCCNGCNCCNGAYAAYTTYTCNAAY ACNTTYAAYTTYCAYAAYGAYGTNACNGARYTNCARCCNACNATHACNGCNGARGGNYTN CARACNGARAAYATHTCNCCNGCNCARAGYCCNCARGAY---------------YTNGAR AAYCARTGGTTYGARATGGARCARTTYYTNAAYGGNACNGTNCCNGARCCN--------- ---------------------------------------------------CARGTNCCN CARGCNATHGCNGTNCCNCCNACNCARGAYGCNATGGGNGTNACNGAYTCNTCNAARYTN ATHAAYCCNATHGTNGAYTTYAAYCARACNGAYAGYYTNTTYACNAAYTCNGAYATGCCN YTNCCNGCNGCNGAYATGGAYTAYYTNGARTTYGGNAAYATGACNATGACNAAYYTNAGY GCNCCNCARGARTCNATHGGNYTNAAYYTNGARTGGGAYGCNTCNYTNAAYTGGGAYTCN GGNGAYGTNGCNYTNTTYGAYAAYYTNACNACNYTNTCNCARAAYGGNACNGAYGAYGTN GAYYTNMGNGAYATGGARGAYYTNTTYAAYAGYATGACNAAY------GCNTCNAGYYTN TTYACNGCNTCNAAYGAYACNGGN------AAYYTNCCNAAYATGYTN---------ATG TCNAGY------------------------GARGAYGGNGCNATGGCNATGCCNGTNAAR TCNTTYACNGARGARYTNAAYGARACNTTYGAYGGNYTNGARGGNGCNACNGGNGGNGCN GAYTAYGAY------------------AGYGCNCCNYTNAARAARATGTCNMGNYTNTCN GARTCNTCNTCNGAYTCNGGNTAY------------GGNAARGGNACNTTYAGYTCNACN TCNTCNTCNTCNTCNTCNTAYGCNGGNAGYCCNTCNGAYGGNAAYACNATGAAYAAYGAR ACNAAYTCNAAYGAYACNGARCAYGAYCCNCAYGGNACNAARGCNYTNGCNCAYCARGTN GCNCAYAAYCAYACNTAYAAYACNYTNCCNGGNCAYACNCCNMGNGARGTNAARAARTAY GCNCAYAARGARCCNTCNAARAARGGNCCNCARTGYMGNGAYGARMGNMGNGCNCARGAR YTNAARATHCCNTTYACNATHGAYGARATHGTNAAYTCNCCNGTNGARACNTTYAAYGAY ATHYTNACNAARCAYAGYYTNACNGARGARCARYTNACNYTNGTNMGNGAYATHMGNMGN MGNGGNAARAAYAARYTNGCNGCNCARAAYTGYMGNAARMGNAARGTNGGNGTNATHTTY ACNYTNGARGAYGARATGGTNGAYYTNCARAARGCNMGNGAYMGNYTNMGNGARGARMGN GCNGCNATGGARAARGARACNMGNATGATGAARGARAARTTYTCNCAYYTNTAYTCNCAY ATHTTYACNTCNYTNMGNGAYGARCAYGGNCARCCNTAYGAYMGNAAYCARTAYTCNYTN CARCARTCNAGYGAYGGNAAYATHTTYYTNGTNCCNMGNAAYGTNACNACNAAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNAAYGAYTAYAARGCNTTYGARTTYATGTTYAARAGYAARAARAAYGGNGTNMGN ACNGAYGCNACNACNMGNGARGAYGTNGARGTNTAYAARTAYYTNTTYCCNGAYAGYMGN TCNYTNACNGGNCCNATHAAYTAYATHMGNGCNGCNTTYYTNCAYCCNTCNCCNTCNTGG GTNGARCARAARGTNACNAARCCNGTNYTNYTNATHTGGGGNTGYMGNGAYYTNGCNYTN GARACNGGNYTNGCNGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGYTNAAYAARATHTCNACNTTY TGYMGNTTYGTNCCNMGNGTNMGNAAYACNMGN---------YTNGGNCAYGGNGTNCCN GCNCAYTGGAARCCNYTNMGNCARGTNTGYGARGARAAYAARAGYCAYATGAAYTGYATG CCNATHCCNCARGGNTCNTGGCARGARGCNCAYAAYGCNAARAGYGCNAARTAYAAYATG YTNYTNYTNGGNAGYTTYGCNAGYYTNGTNGCNACNTTYGGNATHYTNTAYGCNACNGGN ACNATHTAYTTYCAYGGNCCNCCNCCN---------YTNAARGAYAARAGYTCNAARATH AARGTNCCNTCNMGNYTNGCNAARYTNGCNYTNGGNAAYCAYTCNYTNTTYGARAARTGY GCNACNACNCARYTNGTNMGNAARTCNCCNAARGTNGAYGCNGCNGTNAAYTTYGTNAAR MGNYTNGARGARTCNAAY---GCNATHAGYCCNGARYTNTAYGCNMGNGCNAARGCNYTN TCNTGYYTNCARAGYCAYGARYTNATGATGCARTGYYTNCARTCNYTNGARYTNGARAAR ATHTCNGARGCNACNCCNTTYGARACNGCNTTYMGNGGNAARAARATHYTNGARTTYATH YTNGCNAARTTYGCNCARAGYCARAAYGARATHGAYTAYTTYACNAARGTNCARTTYMGN TCNATHAGYAARAAYTCNGARTCNGTNGARGGNMGNAGYAARGAYATGCCNAARTCNYTN TTYACN---AARCCNGAYMGNGGNTCNATHGAYCARACNMGNGAY---------GTNYTN GAYGCNYTNGGNMGNTCNMGNYTNTGGACNCAYYTNCARTTYGARAARAAYGTNTTYYTN YTNMGNCARCAYYTNATGTCNYTNTCNGARGCNGARTGGTGGCARGTNATHGCNGAYCAY CCNGARGAYGARACNGTNGTNCARYTNGTNCAYAGYYTNYTNACNTCNACNGCNGARTTY TTYACNGCNGTNGTNAARAAYCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GCNACNGCNCAYAGYGTNGARGTNAARCARMGNATGGARACNCCNCCN YTNACNYTNMGNGAYTCNYTNCARCARGGNGTNGGNGAYAARGTNTAYGARACNGAYAAY MGNTTYCARCARGARTGGYTNACNGGNGTNAARCARYTNTTY---GAYGAYAAYGAYGTN ATHGCNATGGAYACNAARAAYACNTAYMGNAARAGYYTNCARMGNGARATGCCNCARCAR CCNCARAARTGGTAYAAYATHGARTCNAAYACNYTNCARGAYCARAARTCN--------- ---TTYAARCCNAAYAARGGNCAYAARMGNTGGATHGGNYTNCCNGARTCNATHGTNGAR ACNGAYGGNATGATGGARGCNATGCCNCCNGGNTTYGAYCCNATHTTYATGAARGARCCN GAYCCNAARCARAARMGNAARATHGGNCARAAYAARATHYTNACNTCNATHGTNCAYGAY TGGMGNAAYAARTGGTTYYTNAAYGGNCARTTYGCNGAYGCNACNCCNGARGAYYTNATH MGNGAYATGGCNGAYATHCARCCNCAYGTNMGNYTNAARGCNATHGGNACNGTNGCNAAR GCNGCNGARTAYAARCCNCCNATHGAYTCNAGYATHGCNYTNGAYCAYTCNGARACNGAY CCNATHAAYGAYYTNCCNGARCAYATHTTYGTNGCNYTNGARTGYYTNYTNGAYGAYAAY AAYGAYCARGTNMGNAARGCNGCNGCNATHACNYTNTAYTCNYTNGAYMGNCCNTCNGAR AARGCNATGGTNTGYYTNMGNGARATGYTNCAYAGYGAYAGYACNATHGAYMGNTGGGCN GGNGCNCARTGYYTNGCNCAYTAYGGNGARTGYGAYTCNGAYGTNGTNGCNGARATHATH AARCARATHYTNGAYTCNGARTCNGCNATHAARCAYGARCARGGNATGGCNYTNYTNGCN AARATHAGYAAYAGYAGYACNYTNGTNCAYTGYATGGTNGCNGARCARYTNAAYAGY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNCCNATGTCNGCNMGNTCNGCNMGNTCNGTNACNTCNAAYAAYGGNYTNACNMGNGTN CCNATHACNAGYCAYGAYCARAARMGNATHACNTAYAAYGGNGAYGTNYTNGAYAARMGN TCNTAYTGYTTYACNGARCCNGARAARCCNTTYACNCCNMGNACNYTNAARACNAAYCAY CARTCNMGNYTNAARAAYTCNAARTGYTAYAAYCCNCCNAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TGYGCNTGYYTNGTNGCNGARYTN--- ---ACNAARACNCARGARATHGTNGGNTAYGCNYTNTAYTAYTGGTCNTAYTCNACNTGG GARMGNGTNTAYYTNCAYYTNGARGAYYTNTAYGTNAARCCNGARCAYMGNGGNAARGGN ATGGGNAARCARATGTAYCARGCNGTNGCNAARGARGCNYTNTCNAARGGNTAYAARMGN YTNGARYTNGAYGTNYTNGGNTGGAAYAARCCNGCNAARGARTTYTAYGARAARGTNGGN AAYCARGAYYTNACNGAYACNGARGGNTGGCAYAARATGMGNATGAGYCCNGGNGCNATG GARAARTTYATH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TCNTCNGGNCAYTCNGTNAARATHTAYGARGAYAGYAGYGAY TCNACNGGNAGYGGNCARGTNCAYTGYTCNMGNGGNGTNCARACNGARGAYGTNYTNYTN GARGCNTAYGTNCARAAYMGNCARYTNCARTAYGTNAAYGTNTCNACNGAYAGYGGNAAY YTNTCNGARTGYTTYGAYCARGARGCNTTYGAYYTNATGGCNAAYGARAGYATHCCNGAR AGYTAYTGGAARGAYGTNGCNGARCARMGNMGNYTNGCNYTNAAYGAYACNYTNGARGAR AAYAARAAYYTNTCNTTYGARATHGARACNYTNAARGARGARAAYMGNMGNYTNTCNGAY ATHGCNGCNAARGCNGARCAYYTNGARAAYYTNYTNTCNGAYAAYGARGAYGARGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARMGNTCNACNTCNGCNATHTGYGCNCAY YTNGCNATHGAYTCNGCNCCNGARTCNGTNYTNAAYACNYTNACNGAYGTNTGYCARGAR TTYTTYAAYCARTTYACNAARCAYYTNAGYGTNGCNACNGAYMGNCARGCNATHCAYGGN TCNTCNGGNTTYCCNGAYGCNATHGARMGNGTNYTNCAYGARATHGGNATGGGNAGYATH ACNGAYATHCAYTCNTTYTAYCARAARMGNGTNYTNGCNTAYCAYAAYMGNGTNAARCAY CARTGYCARGCNGTNATGGCNCARTAYAGYTCNYTNGCNAARCAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNTTYTGGAGYATGAARTCNYTNCCNGGNYTNCARYTNGGNMGNYTNYTNAAYGAYGAY GTNACNCARCCNGTNAAYGTNGAYYTNTTYGTNYTNCCNAGYTTYYTNGARTTYGARGAY YTNGTNTGGTCNAARGARAAYTCNTCNYTNTCNCARTGYAAYTTYGTNCARATGTTYATG GAYCCNAAYGTNGARYTNATHCAYGTNAARGARAAYGGNTTYATHGGNACNYTNTTYYTN CCNCCNGGNGAYGGNCCNTTYCCNGCNGTNACNGAYATHTTYGGNATGAAYAGYACNGAY CCNTGYCAYMGNTCNTCNYTNYTNGCNTCNMGNGGNATHGCNTCNATGGTNGTNACNTAY GTNGGNAARGARGGNACNGCNCARACNAAYGAYGAYYTNGAYTTYCAYTGYTTYYTNMGN GCNTTYGAYTGGYTNTCNAAYCAYCCNAARGTNGAYTCNAAYTCNATGGGNGCNYTNGCN TCNTGYTCNGCNTCNTTYTAYACNAAYGTNATHGCNTGGAARMGNCCNCARGTNAARTGY YTNGTNACNATHAAYAAYACNTTYGGNCCNGCNGCNYTNGCNCARCAYGTNGARGGNMGN AGYTGYTGGCCNYTNGAYYTNMGNAARGCNACNATHATHGAYGGNTGYYTNATHYTNAGY TCNATHATHTGYTGGGAYYTNGTNAARACNYTNCARCCNTTYCCNTAYTGGMGNCAYGGN GCNAARGTNYTNGARATHACNTGYGARGAYGAYYTNTGYATHAAYCCNGAYATHTCNACN ATGGTNCARAARCARYTNCCNYTNGARTTYGCNGAYAAYTTYGARTTYATHMGNTAYCCN GGNGCNGGNCAYATHYTNGAYACNCCNCAYCAYCCNYTNTGYGARAGYGTNTCNAAY--- TTYTTYGGNATGAARTGYYTNTGGGGNGGNACNCCNAARCARCAYGCNTAYGCNCARGCN GAYAGYTGGCCNMGNATHATHTCNTTYTTYCARAARCAYYTNAAYGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNTGYGCNAAYGARYTNCCNCCNGGNGAYYTNGTNGCNCAR GGNGAYGTNATHGTNGTNACNTTYAAYTAYMGNYTNTCNTGGYTNGGNTTYGTNAARGGN CCNACNGAYGARATHAARGGNAAYATGGGNYTNTGGGAYCARYTNGARGTNYTNAARTGG GTNAAYAARAAYATHATHTCNTTYGGNGGNGAYCCNGAYGAYGTNACNATHGCNGGNGAR TCNATGGGNGGNGARAGYGTNTCNGCNTTYAGYGTNATGAGYCARGCNAARGAYYTNTTY ACNAARGGNATHYTNATGAGYGGNACNATGTTYGCNTGYMGNTCNACNGTNGGNTCNTCN GAYGTNYTNYTNGAYTGGYTNATHAAYAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CCNGTNTTYGARGAYAARATHGTNAAYGTNACNGTNGARGCNGGNTCN ACNGCNACNYTNCCNTGYTCNGTNYTNAAYYTNMGNAGYCAYCARYTNGTNTGGTCNGAY CARTAYGCNACNYTNYTNACNCAYCARGAYAARMGNGTNATHGAYGAYGAYMGNYTNAGY ATHGARMGNCCNTAYGAYMGNGAYTGGAAYYTNCAYATHMGNGAYGTNMGNCCNAGYGAY CARGGNYTNTTYAAYTGYCARATHAAYACNGAYCCNGTNATGATHAARACNGTNAAYYTN ATHGTNCARGTNCCNGCNAARATHGTNGAYCAYGCNTCNTCNMGNAAYATGACNAARGAR CAYGGNAARGCNGARYTNACNTGYAAYGCNACNGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR ATGAARGTNAAYTGGGCNGCNTCNCCNAGYCARGCNCCNAARCARGAYACNAGYAARCAY CAYCAYGTNTTYGTNGGNGAYYTNAGYGGNGAYATHGARCAYCAYCARYTNMGNGAYGCN TTYGCNGGNTAYGGNGARATHTCNGAYTGYAARATHATHMGNGAYGTNAAYACNAAYAAR TCNAARGGNTAYGGNTTYGTNTCNTTYGTNAAYAARCARGARGCNGARTTYGCNATHAAY CARATGAAYAAYCARTGGYTNGGNTCNMGNCCNATHMGNACNAAYTGGGCNACNMGNAAR CCNYTNGCNCCNGTNGCNAARGARAAYGCNAARCCNYTNGCNTAYGAYGARGTNTTYAGY CARTCNAGYTCNACNAAYTGYACNGTNTAYTGYGGNGGNGTNACNAAYAAYYTNACNGAR GARGTNATGMGNAARACNTTYGCNCARTTYGGNACNATHCARGARGTNMGNGTNTTYAAR GAYAARGGNTAYGCNTTYATHMGNTTYAGYACNAARGARGCNGCNACNCARGCNATHTGY ACNGTNCAYGGNACNTCNATHAAYGARCARTCNGTNAARTGYTCNTGGGGNAARGARTCN AAYGARGGNAAYCCNACNAAYCAYCAYCARTCNAAYCCNCCNGTNGTNATGYTNCARTCN CARCARCARCCN---YTNGCNGCNGCNCCNGCNGCNGCNCARTAYGGN---CARTTYTAY AAYATGAAYTAYTAYCARGGNACNCCNTAYGCNGCNGGNACNCCNACNTAYCARAGYGCN ATGCCNGCNCARGGNCARTTYATHCCNTCNGGNGCNGGNCARTGGCCN---GCNTAYTCN AAYTAYCARGCNTAYGGNAGYATGAAYGTNCCNGTNAGYCARTAYGCNGGNYTNCARATG CARCCNGGNGCNCARCARCARCARTTYAGYGGNCARACNCARGGNATGGTNGGNTAYCCN ATGCARCARGGNATGGCNMGNTCNAAYGTNMGNTAYGARGTNYTNCCNTCNGARGARCAR AAYGTNGCNGCNGARCCNGTNAAYATGGCNATGGTNATHCCNCCNCCNAGYTAYTCNGAR AAYGCNGTNYTNGARCARAAYGGNGAYGAYCCNGCNTTYGGNCCNGCNAARYTNCCNAAY TAYGTNGARGCNACNACNYTNCCNTCNTAYGARGARGCNGARMGNACNAARGCNGARCAR GCNGCNGTNTCNGAYACNGAYMGNAGYGAYTGYGARTCNGGNMGNYTNATGATGYTNGAR GGNGTNAAYGARACNACNATHGGNACNGAYGGNATGTTYATGTGYACNTTYTTYATHTCN TTYYTNTTYAAYTGGYTNGGNTTYYTNYTNTCNYTNTGYYTNTCNAAYACNATHGCNGGN MGNTGYGGNGCNYTNTCNGGNYTNGGNYTNTCNATHGTNAARTGGGTNGTNATHGCNAAR ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNAARGTNCAYACNGARCARGTNGTNAARAAY GAYAARTCNACNGAYYTNACNGTNYTNTTYYTNCAYGGNATGMGNTTYTCNTCNAARAAY TGGYTNGAYATHAAYACNYTNTTYCAYGTNGCNAAYTGGGGNTGGAARGCNGTNGCNGTN GAYYTNCCNGGNTTYGGNCARACNAARGAYAAYATHGAYCARGARTAYAAYGCNGAYTTY YTNTCNTCNYTNATHTCNGCNYTNGGNYTNATHAARCCNGTNATHGTNTCNCCNTCNATG AGYGGNTCNTTYTCNYTNCCNTTYGTNTTYGCNGAYGGNGTNAAYGGNYTNGARMGNGCN YTNGGNTAYATHCCNGTNGCNCCNGTNAGYACNGGNGCNTAYGTNACNAAYTTYGARAAR AGYGARATGCCNACNYTNATHGTNTGYGGNTCNMGNGAYAARAGYATHGGNGCNACNAGY AAYAARCAYYTNGGNCAYYTNCCNAARGGNATHCCNGCNYTNATHGARGAYGCNGGNCAY GCNTGYTAYYTNGAYAAYCCNGAYYTNTTYCAYAARTAYGTNTTYTAYTTYYTNATHAAY YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARGARYTNACNACNMGNYTNAARTCNAARAAYGCNGAR TTYACNAAYCARTCNYTNGARGTNTCNAARYTNAAYGAYCARATHMGNGCNYTNGARTCN ACNYTNGCNGARGCNAARGARAGYATHAARAAYCAYAARACNGARACNGCNGCNTGGAAR AAYMGNTAYTGYYTNTCNMGNGAYGARAGYGAYMGNYTNACNCARGARGGNAARACNAAR GARGAYCARATHCARACNYTNACNGTNCARYTNCAYGARTCNYTNCARCARACNATGGCN YTNCARAARGCNYTNTTYACNAGYTGYGARMGNGARAARTGYAARGARGARGTNATGAAY TCNGTNMGNAARCARCARAARMGNACNATGCARGARATGGCNAGYYTNMGNAARYTNTAY GARATGCARTCNAARGAYYTNACNYTNTAYCAYYTNAGYGTN------------------ ------------------------------------------------------------ ------------------------------------------------------ATGTCN TCNGAY---GARYTNGAYATGGTNAAYMGNGAYCCNAAYAAYYTNAAYGAYCAYGTNAAR GTNTGYTTYGAYGARGTNATHGGNGARCCNGAYGGNGCNCAYTCNATHAAYTGYGTNTGG TCNAAYTCNTAYGCNTGYTTYAAYTGYTGGAARTCNTGYTGYTAYAAYYTNYTNACNATH YTNTGYGCNATHCCNATHTCNATGTGYTGGGGNTGYGARTTYGCNTAYATHACNTTYACN CAYGTNTGGCARGTNACNCCNTGYATGMGNGCNTAYATGATHAAYTGYGGNTGYATGCAR AARTTYTAYGGNACNTGYYTNCARTGYTGYATGCARCCNTGYTTYGARTCNATGGGNTAY TTYTTYAAYAAYATHAARGTNACNAAYGTNAGY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TCNMGNYTNAGYCARTCNGTNGGNAAYCAYAAYAARGAY TAYACN---------------------------------GAYACNAARGARYTNTGYMGN MGNYTNGARGAYAARATHAAYAGYYTNACNGGNATGGGNAARAAYYTNCARAARGARAAY MGNGARATGGCNAAYYTNATHGAYMGNCARGGNGARAARYTNGAYTCNGTNAARATGAAY GARMGNAARGCNMGN---------------------------------------TCNAAY TGGAAYCARGARACNAARGCNMGNYTNAAYGARAARGTNACNTCNAAYGTNAAYGAYGTN GGNTCNYTNATHMGNCARGTNATHMGNTCNTCNAARACNAAYGAR--------------- ------------------------------------------------------------ ---------------------------TTYYTNGCNCARGCNGCNAARGGNTGYTCNACN GARACNATGAARAARATGAAYGCNGTNAARTCNCARGCNTCNATHTCNMGNAGYGAYCAR YTNGCNACNYTN------------------------CARCAY------------------ ---------------------TCNAARCCNTCNGAYCAYGTNYTNYTNTTYCAYTGYTCN ACNTTYGARYTNCAYATHGGNYTNCCNGGNATHGCNGTNAAYGTNGARCAYGTNAGYAAR CARGTNGARAARGCNAARGARAARGCNGARAGYGTNATHMGNGAYGCNGCNGAYATHYTN MGNCARAARGGNATHCARTGYTAYTCNGTNATHGARAAYMGNCCNAARCCNCAYGARGCN ATHYTNGARGTNATHGARMGNGARAARGTNGAYTAYGTNGTNATGGGNACNMGNGAYYTN GGNTCNGTNMGNMGNGCNYTNGTNGGNAGYGTNAGYACNGARGTNGTNCAYCAYGCNAAY GTNCCNGTNACNGTNGTNAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNAARYTNGTNACNCCNTCNTCNAGYYTNGARATHGTNGAYGGN---------GGN AARGAYAGYGCNTGYGGNTTYTAYGAYGAYMGNACNTGYCARGAYTCNGTNMGNTCNTGG TCNMGNTCNAGYGCNGGNTCNATHCCNCCNMGNAGYGAYTCNTCNYTNAAYMGNMGNACN GTNACNCCNACNAARCARGTNTCNYTNCARGCNGTNMGNMGNAARGARGARAGYTCNGAR CCNTTYGTNGAYCAYATHGAYGTNGGNAGYGTNMGNACNGARGAYATHMGNCCNAARGCN TGGGAYGARCCNTCNCAYGAYTTYTCNCARYTNTCNACNGGNGAYAAYMGNCARAGYGAY CCNAGYAARCARGAYTTYGCNAGYCAYTCNTCNCAYACNAAYCCNGGNCARACNCARAAR GCNYTNTCNAARCCN---------YTNGGNCARCARCAYAAYAARCAYGTNATHGAYAAY AARGAYATHCCNAGYTCNAGYTCNGAYGARGAYGAYGAYGAYGARGARGAYGARGAYAAR GAYGARAAYGAR------AARYTNAARGCNCCNACNGARYTNYTNATGGARTTYATHGAY TGYYTNATGAARAARGAYTTYCCNAAYGCNAGYAARYTNTGYAARATGATHYTNYTNTAY GARCCNGARAAYGARGARGCNYTNAARTTYCARCCNYTNATHGARGARAARATGGCNYTN GAYGCNGCNGCNGARGAYGARGARGGNAGYGGNGAYGARGAYGAYGAYGAYGAY------ ---------------------TCNMGNYTNGTNTGGATHGAYYTNGARATGACNGGNYTN AAYATHGAYMGNGAYGTNATHYTNGARATHGCNTGYYTNGTNACNGAYAARCARYTNAAY ATHGTNGCNGARGGNCCNGAYYTNGTNATHCAYCARACNGAYGARGTNYTNGARAARATG AAYGCNTGGTGYATHGARCAYCAYGGNAARTCNGGNYTNACNGAYGCNTGYMGNGCNTCN AARGTNAGYACNAARGARGCNGARAARATHGTNGTNGAYTTYYTNGARCARCAYGTNGCN AARGGNAARTGYCCNATHGCNGGNAAYTCNGTNGGNACNGAYAARCARTTYATHACNAAR TAYATGCCNYTNYTNGAYGARCARYTNCAYTAYMGNATHGTNGAYGCNAGYACNGTNAAR GARYTNTGYMGNMGNTGGTAYCCNAAYGARCCNAARAARAARYTNTCNCAYMGNGCNATG GAYGAY---ATHMGNGAR------------------------------------------ AGYATHGCNGARYTNAARTTYTAYMGNCARAGYATHTTYAARYTNGAYMGNGTNGAYGCN ACNGAYGCNCAYAARTTYAGYTGYCAYTTYGGNACNACNTAYAARGTNGTNGTNGTNCCN AAYGARGCNTCNACNTTYATGTCNTGYGGNGAYGAYGGNACNGTNMGNTTYTTYGAYYTN MGNGTNAARACNAGYTGYAGY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TTYGARGGNTAYAARTTYATHGARGTNTTYCCNGARACNCARAARGAYGTNGAYTTY YTNYTNCAYTTYGARATGGARCAYAARAARYTNACNYTNATGGARGTNCCNATGTCNGGN GARGGNGTNTCNYTNTGYGTNCCNCCNGARYTN--------------------------- ---------ATGGAYACNGTNGTNGCNGCNYTNYTNCARAAYAAYATHGCNTTYGARGTN TCNGAYACNAAYGTNGCNCARATHGTNGARTCNAARMGNGCNACNGAYGGNTAYGTNGCN AAYCAYAGYAAYTAYCAYAGYTAYGAYCARCAYGTNGCNTAYTGGAARATGTTYGARYTN AARTAYCCNGAYGTNGTNAARGTNACNAARATGYTNAAYAARACNGTNGARGGNMGNGAY ATGTAYTAYGTNACNYTNAAYGGNACNAARAARTGGGAYCAYAARCCNACNATHACNATG GARGCNGCNGTNCAYGCNMGNGARTGGATHTCNCCNGCNACNGTNYTNTAYTTYATGGAY AGYATHYTNAARMGNTAYGAYGARGGNGARGCNAAYGCNGTNTTYATGYTNGAYTAYTAY ACNTGGAARATHTCNCCNYTNACNAAYCCNGAYGGNTAYGARTAYAGYMGNACNAARGGN AAY---MGNYTNTGGMGNAARAAYMGNMGNGTNGAY---GAYTAYTGYGAYGGNGTNGAY YTNAAYMGNAAYTAYGAYYTNAARTGGGAYYTNGGNCCNTGGTAYGTNAARAAYTGYACN ATHGTNTAYMGNGGNCCNCARCCNTTYTCNGARCCNGARACNGCNAAYYTNGTNMGNYTN ACNGAYGARACNCCNTTYCAYTAYACNCAYTTY---TCNGTNCAYAGYTAYTCNCARATH ATGYTNYTNCCNTTYGGNTAYGCN---GTNAAYGCNACNCARGARAAYTAYGAYGCNTTY YTNAARACNGCNAAYGTNATGGCNGCNGCNATHAAYGCNACNAGYGGNAAYCARTGGMGN GTNGGNCARGCNMGNCARYTNYTNMGNTAYGTNTCNACNGGNACNYTNMGNGAYTGGATG GCNACNAARAARCCNAAYYTNTTYGCNYTNACNTTYGARYTNMGNCCNGARMGNTCNGAY AARMGNGGNTTYATHATGCCNGTNACNGARATHATHCCNTCNGGNGTNGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARTGYGCNACNTCNCCNGTNAAYTGGACNGGNGGNGARCCNMGNATGAARTGYCCNAAY MGNTGYACNACNGTNGGNGARTAYGAYGCNGCNACNGGNAARCCNACNTTYTTYTAYMGN GGNTGYGGNGTNACNACNGARGCNCARAARGAYGGNTGYCAYAGYAAYGGNGCNMGNGAY AGYTGYTTYTAYTCNTGYGGNGAYGGNAARGAYTAYTGYAAYGAYGCNTCNATHCCNACN TCNCCN---------------------------------------------------YTN GARGARGCNTGYAARATGGCNGCNGGNGGNATHGGNAARGAYTGGAARGCNGTNTAYTAY MGNYTNCCNTTYGAYCCNCCNMGNGAYTCNACNMGNYTNCARMGNGAYGTNTCNGTNYTN GAYCAYYTNGCNTTYMGNAGYGAYGTNCCNGARGARAARCARGCNYTNAARTGYYTNCAR MGNTGGMGNACNYTNCAYMGNAARGGNGAYATHCAYGARYTNATHCARGCNYTNAARGAR GTNAARAARAARAARYTNGCNMGNCARYTNTCNAAYMGNTTYGTN--------------- ------------------------TTYAAYTCNGTNYTNGGNAGYATGYTNGGNATHGTN ATHACNCCNTTYYTNATHYTNYTNYTNYTNGGNAARGAYGGNGAYATHCCNACNAAYMGN ATHTTYCARCARYTNTTYYTNACNGTNGTNGTNCCNYTNYTNGTNGGNCARYTNATHMGN AAYTAYAARTTYMGNTGGYTNCARMGNCAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHGCN GTNGGNTTYGTNTCNTGYGAYCAYMGNGTNYTNTCNATHATHYTNYTNACNGCNGCNGTN GGNTTYGARGGNATGTCNTAYGGNGGNTAYATGGTNAAYCAYGTNGAYTTYGCNCCNMGN TAYGCNGGNGTNYTNTAYGGNATHACNAAYACNATHTCNACNATHCCNGGNATHYTNGCN CCNATHGTNACNGGNGCNYTNACNCCNAAYAARACNCARGARGARTGGMGNAAYGTNTTY TAYYTNTGYGGNGCNTTYTCNYTNGTNGGNGCNATHGTNTTYGGNYTNTTYGCNCARGGN GARACNGARGCNTGGGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CARAAYAARACNACNCCN GTNCARGARAAYMGNMGNGAYAARGAYMGNCCNCCNTCNAARATHGTNATHMGNMGNYTN CCNCCNACNYTNACNCCNGAYAAYTTYYTNGARCARGTNTCNCCNYTNGCNGAYCAYGAY TTYTTYTAYTTYGTNAARGCNGAYATGAGYYTNGGNCARAAYGCNTTYTGYMGNGCNTAY GTNAAYTTYYTNAAYGCNGARGAYATHTTYATHTTYMGNGAYAARTTYGAYGGNTAYGTN TTYYTNGAYGARAARGGNGGNGARTAYCCNGCNATGGTNGARTTYGCNCCNTTYCAYAAR GTNCCNAARMGNAARGCNAARAARAGYGAYTCNAARTGYGGNATHATHGARCARGAYGTN GAYTAYATGAARTTYYTNGARYTNYTNACNAAYCCNCCNGARGTNGCNCCNATHTCNYTN GAYGCNATHGTNGARGARGTNGARGCNAARGARCARMGNYTNGCNAARATGGGNTCNACN AARACNAGYACNCCNYTNYTNGAYTTYYTNMGNMGNMGNMGNGARGARAARMGNATGAAY ATG------GTNAARGARGAYMGNAARMGNGGN------------------TAYGAYMGN MGNMGNTCNGGNAARGAYGAR---------------GGNGGNGGNGGNMGNGAYMGNGAY MGNGAYMGNGAYMGNGARMGNCARAARGARMGNGARMGNMGNMGNGARMGNATGAARGAR TTYTCNAARGARMGNGAYMGNGARMGNMGNMGNGAYMGN------------GGNGGNMGN CARMGNGAYGGNMGNAGYGGNTCNGGNMGNTAYMGNGAYGARGARGARMGNCARAAYAAR CCNATHATGYTNYTNAARAARGCNGARTCNGAYAGYTCNTCNAARGAYGARACNTCNGGN TAYMGNAAYMGNAARGARGAYGCNACNGCNCARAGYAGYMGNMGNGAYGAYGARACNGAY AARGGNGGNGAYAARGGNGGNAARGAYMGNMGNGGNGGNAAYGGNGGNMGNYTNMGNAAR GARGARGAYMGNGGNMGNAARGAYTGGGAYGAYMGNCCNCCNGGNMGNGAYMGNGGNGGN GGNGGNGGNGGNGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CCNTCNGCNGARAGYAARTCNTTYAARATHAARTAYGGNATHGAYGTNTCNGTNAGYTTY AGYAAYGGNCAYACNGARACNYTNTGYYTNGTNATHCCNGGNGTNYTNCCNCARACNAAY AARAARTGGGAYGARTGGAARGCNGCNGAYTGGATGTTYGGNTGYGARACNAARTTYTCN AAYTCNYTNTTYTCNCCNGGNCARCAYYTNYTNCAYACNGARTCNTTYTCNAGYYTNCCN TCNTTYCARGTNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARACNATHMGNGGNGGNGGNGARATGTTYAARTTYCCNTGGACNACNTAY TCNAARATHCARCARTTYCCNTTYAARTTYTAYTGGAARCAYGGNMGNYTNTTYMGNTAY GTNGTNTAYTCNTCNATHYTNGTNTTYCCNYTNATGGCNAARYTNACNAARGCNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGGCNGAYACNYTNCARYTNYTNAARTGY GGNGTNMGNTTYTCNCCNCCNACNYTNGTNGTNACNTAYAARGAYTGGAARTCNGGNAAR ATGMGNMGNMGNTCNATGCCNYTNMGNAAYTTYACNAARCAYAGYGGNGTNGARMGNGTN TAYCARGAYYTNAARGAYAAYCCNMGNCAYGGNAARTAYGTNMGNYTNATHTCNCCNATH CARATGCARMGNYTNYTNACNATHGTNAARGAYAARGTNAGYGGNYTNAGYYTNGARGCN AGYATHGCNMGNAAYAAYGARATGGARGCNYTNAAYCCNGARGARAAYYTNAAYACNGTN GAYGARGARACNYTNAARMGNAARAARYTNGTNATGAAYTCNTCNTTYGARAARAAYCAR AARAARYTNGGNGAYCCNGAYTTYGARTAYAAYGTNGARGTNGAYTTYGARGCNGGNGCN ATHGARACNAGYGGNTGGGAYGARTCNGAYTCNGAYGTNGGNTTY >auritulus YTNATHATHGCNCCNYTNYTNYTNGGNGTNGCNYTNGCNGGNTAYGAYCCNTAYTCNGAY YTNGCNCARYTNTAYMGNATGCARYTNYTNGCNGAYGCNTTYGGNGAYTAYATHCCNGAR GAYGGNCCNYTNCCNGTNGTNGCNGAYMGN------------TCNTAYTGGCCNGARTTY GCNGCNTCNYTNGAYGARGCNGCNGCNGGNCCNCARGAYGAYATHTCNCCNTAYGCNTCN GCNCCNATGTAYAGYGGNGCNCAYATHMGNGAYCARGARCAYATHGARCAYAGYGCNYTN CAYGGNTAYCARTCNGTNGCNGGNGGNACNGCNGARGGNCCNGCNAAYAAYAARATHCAR AARAGYGAYAARCCNYTNCCNGCNTAYTGYAAYCCNCCNAAYCCNTGYCCNGTNGGNAAR ACNGCNAARGAYGAYTGYGTNGARGAYTTYGARAAYTCNGCNGARAAYAAYAARAARYTN YTNAGYGARCARGAYTGYCCNTGYGAYACNGARCAYATGTTYAGYTGYCCNGCNGGNMGN GARACNGTNTCNTCNAARGGNAAYTCNGGNTAYCARCARACNYTNAAYAARGTNATHGAY CARYTNAGYAARATGAARCCNGAYTCNGCNAGYCARGARAAY------------GGNGCN YTNMGNAARMGNATHGCNYTNGTNGCNAARAARTCNCCNCAYATHATHCAYAARMGNGAY GARGCNTCN------YTNAAYCCNTAYATHACNGGNCCNCAYAARAGYATHGCNGCNAAR AARTCNGGNCARATGTCNCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ACNYTNGCNAARACNAARCARAARAAYAAYTCNAARYTNCARAARGARMGNAARGTNGTN MGNATGGTNGTNYTNATHTCNGTNGTNTTYYTNATH---TCNTAYATHCCNAAYYTNATH TTYYTNATHATGACNTTYYTNTCNAAYATGMGNYTNATGGGNAAYTTYCAYAAYYTNAGY YTNYTNATGATGGCNYTNACNTTYYTNTTYGARGGNATHAAYTCNAGYATHAAYYTNATH GTNTAYYTNTCNATGAGYTCNAARTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNCAYTTYAAYGGNGTNGARTAYGTNTGYTGYCCNCAYAARTCNAGYACN MGNGTNCAYCCNGARCCN---AARGAYTCNGAYGAYAARCCNCAYAGYTGGGARGAYGAY AGYGARGARGAYGARGAYGARTAYGAYAGYGAYGARGAYGAYGAYGAYGAYGARTAYGAY TAYTAYTCNACNTCNACNTCNTCNTCNTCN---------------TCNAAYAGY------ ---------------GARGARTTYCCNGARGARAAYGTNGTNGAYYTNTAYGARGCNTAY YTNMGNGGNCARCCNTTYCCNTCNAARTAYAAYAAYGARCAYAARAARTTYYTNGCNGCN AARGARMGNATGAARATGAAYCARAARAARAARGTNGCNAARYTNYTNCARGARTGGGAR GARGCNMGNGARCAYGTNAAYGTNGTNMGNAARACNGAYCCNAARACNGCNGAYMGNATG AAYGAYGARATHGCNCARMGNTTYAARCAYYTNTAYGCNTCNTTYAARYTNGARGAYGCN AGYGARAAYAARCARYTNGCNGCNYTNCAYCARCARCAYATHCARGCNATGYTNAAYGAR MGNAARMGNGARGCNATGGAYMGNTAYATGAAYGCNYTNGARAAYGGNAAYGTNGCNATG GTNAARAARTAYYTNCAYAGYTAYATHAARGCNGARGARAARGAYMGNATGCAYACNGTN AAYCAYTTYGARCAYATHMGNAAYTCNAAYGCNAARGARGCNYTNMGNATHCAYMGNCAY ATHATHAAYCAYYTNAARYTNTCNGARATGMGNATHGAYCARGCNATGGARATGYTNACN CAYTAYCCNTCNATHGARTTYGARGTNMGNCCNGARATHGARAAYTTYYTNAARMGNTTY AAYGARATHGCNAAYAGYATHAARAAYGTNGTNYTNCCNGTNCCNGARGTNGAYAGYCAR GARGARTCNAGYTCNAGYAARGAYGAR------------TCNGAYGAYGGNTAYACNACN TCNAAYGAYATHAGYTAYGAYAGYCARGTNGARAGYGARGARCARACNGARGAYGAYGTN GAYGARCCNACNCCNAAYTCNAGYATHGARAGYGAYTCNGCNATHGAY------------ ---------------------------GAYGARGTNCARGARGAYGARCAYAGYTAYGAR MGNGCNTCNCARTTYGTNGCNCAY---GCNCARCARAGYATGCAYGARAGYAGYGGNYTN AARTCNGCNACNGCNTCNGGNTCNCARATGGGNAGYACNATHGGNATHGCNYTNGGNAGY GTNAGYGTNTTYGTNATHGTNATHGTNGCNGTNATGATGGTNMGNCAYAAYMGNCAYMGN CARCCNGTNTCNCAYGGNTAYGTNGARGTNGAYCCNTCNGCNAGYCCNGARGAYMGNCAY YTNGCNAAYATGCARATGAAYGGNTAYGARAAYCCNACNTAYAARTAYTTYGARGAYCCN CCNAARGAYAARYTNTAYMGNCARATHACNGTNGARGTNAARGGNCAYGAYCCNGCNGTN YTNAAYAGYTAYCARAARTTYACNACNACNGCNGCNGARCAYYTNGGNGTNAARATHGCN AGYATHTCNGARCCNCCNMGNGTNATHACNMGNAARAGYYTNYTNAARTCNGTNTTYATH TTYAARAARCAYATGCAYCARTAYGARACNMGNACNYTNTTYMGNGTNTTYGARTTYAAR CAYYTNACNGARTCNACNGCNYTNACNTTYYTNGARTAYATHCARMGNAAYYTNCCNGAR GGNATGGCNATGAARGTNACNAARCAYGARYTNCARCCNYTNCCNGAYCAYYTNAARCCN CCN---------------------------------GAYTAYTTYAAYGTNATGYTNGGN TCNCARYTNYTNTAYAARTTYGARMGNCCNCARTAYAGYGARATHYTNGTNGARCAYAAR GAYAARCCNATGTCNAGYYTNTAYGGNGCNACNCAYYTNYTNMGNYTNTTYGTNMGNYTN GGNGCNATGYTNGCNTTYACNTCNYTNGAYGARMGNACNGTNCAYATHYTNYTNAAYCAY GTNCAYGAYTTYYTNAARTAYATGTCNAARAAYGGNTCNTCNYTNTTYAARACNTCNAAY TAYGARATHGCNACNCCNGAYTAYCAYMGNAARGCNATH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARYTNTGGYTNCCNGAYATHGTNYTN TAYAAYAGYGCNGAYGAYTTYACNGCNGGNTAYATGAAYAGYAARGCNATGGTNMGNCAY GAYGGNAAYGTNTTYTGGCCNCCNCCNGCNAARTTYMGNAGYTCNTGYACNATHGAYATH ACNTAYTTYCCNTTYGAYGAYCARATHTGYGARYTNAARTTYGGNTCNTGGACNTAYGAY GGNTTYCARGTNGAYATHACNAAYMGNGCNGCNACNGTNGAYYTNCARAAYTAYGTNYTN AGYGGNGARTGGGARYTNGTNAARGTNGGNYTNAARMGNACNGARGTNACNTAYGCNTGY TGYAARGARCCNTAYCCNGAYGTNMGNTTYACNATHGTNATHMGNMGNAARACNYTNTTY TAYYTNTTYAAYATHATHTTYCCNTGYYTNTGGYTNACNATHYTNAGYYTNYTNGGNTTY TGGYTNCCNCCNGAYTCNGGNGARAARATHACNYTNGGNATHACNGTNYTNYTNGCNTTY TCNGTNTTYATGYTNYTNATHGCNGARAGYATGCCNGCNACNTCNGAYTTYGTNCCNYTN ATHGGNATHTAYYTNACNGTNACNATGGGNATGACNTCNYTNTCNATHATHYTNACNGTN TTYGTNYTNCARYTNCAYCAYATHGGNCCNCAYCARAARCCNGTNCCNMGNTGGYTNMGN ACNATHGTNTTYAAYTTYYTNGCNMGNYTNGTNTGYYTNTGYTGGGARYTNYTNGCNGTN AARCARAARMGNAAYATHGTNTTYTAYGCNTGYTGYCCNGARCCNTTYCCNGAYGTNACN TTYACNATHGTNYTNMGNMGNAARACNAARTAYTAYTTYATGAAYATHYTNATHCCNTGY ATHYTNYTNAGYTTYYTNTGYYTNGCNGGNTTYYTNYTNCCNCCNGAYAGYGGNGARAAR GTNACNYTNGGNYTNAGYGTNYTNYTNACNATHACNGTNTTYATGYTNATGGTNGCNGAY MGNATGCCNCAYACNTCNGTNCAYGCNYTNGCNNNNAANCARNNNNNNNNNNNNYTNGAR TCNAAYCCNACNACNYTNAAYAARTAYGTNCAYGGNYTNGGNATGGAYAARGCNTGGAAY TTYGTNGAYGTNTTYGGNYTNGAYCCNGAYYTNYTNGCNATGGTNCCNMGNCCNGTNGCN GCNGTNGTNYTNYTNTTYCCNGAYTCN------------------CARACNGCNYTNGGN GARTAYATGAARGARGCNCAYGAYGAYYTNTAYTAYACNAARCARACNATHGGNAAYGCN TGYGGNACNGTNGCNYTNGTNCAYGCNYTNGCNAAYAAYCARGAYAARATHACNTTYGAR GARAAYAARNNNTTYTCNAAYTTYYTNAARNNNACNAARTCNNNNAGYCCNGARGANAAR GCNAARCAYYTNGARGARGAYATGGCNATGGGNGCNGCNCAYGARGGNTGYGCNCARGAR GGNGAYACNGCNGCNCCNGCNGCNTCNGARAARGTNAARTGYCAYTTYGTNGCNYTNGTN CAYTTYAAYGGNACNYTNGTNGARYTNGAYGGNAGYAARGAYGGNCCNGTNTCNCAYGGN TCNACNTCNGCNGAYAAYYTNYTNGARGAYGCNGCNGTNGTNGTNAARAARTTYATHGAR AARAAYCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GAYAAYGTNCARTAYATHGARYTNMGNTCN YTNTTYGCNGGNATGAAYGAYYTNGARGGNAAYGTNTAYGGNAARGAYMGNGCNTTYGAR ATHTAYMGNGARGTNACNGARGARTTYAARAARAGYCAYCCNGAYTTYGTNGGNGCNAAR TTYATHATGTCNGAYATHMGNGTNTTYTCNCCNGAYGTNATHYTNAARTCNATHAARGAR ACNATGGARATGMGNAARGCNCAYCCNGAYTCNYTNYTNGGNTAYGAYYTNGTNGGNCAR GARGAYCCNAAYCAYCCNYTNYTNTAYTAYAARGAYCCNYTNYTNTAYCCNAGYCARACN GAYCCNCARAAYCCNYTNCCNTAYTTYTTYCAYGCNGCNGARACNAAYTGGCARGGNACN GCNACNGAYTAYAAYYTNATHGAYGCNATHYTNYTNAAYACNACNMGNATHGGNCAYGGN TTYGGNYTNGTNAARCAYCCNAGYATHGCNAARGARGTNAARGCNAARGGNATHGCNGTN GARGTNAAYCCNATHTCNAAYCARYTNYTNGGNYTNATGACNGAYATGMGNAAYCAYGCN YTNGTNCCNYTNATGGCNGAYGAYTTYCCNGTNGTNGTNAGYTCNGAYGAYCCNGCNACN TGGGARGCNGAYCCNYTNTCNAGYGAYTTYTAYATGGCNTTYATGAAYATGTGYGGNGAR GAYGCNGAYYTNMGNTTYYTNAARCARYTNGCNATHAAYTCNTTYAARTAYAGYGCNATG AAYCARGARGARAARGAYAARGCNATGGARYTNTGGCARGTNAARTGGGAYGCNTTYATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARMGNCAYYTNAAYYTNYTNMGNYTNGGNAARMGNAAYYTNAAYATGYTNMGN YTNGGNAARMGNCARGGNAGYGGNGTNGAY------------------------------ GGNGAYGAYGTNGAYGAYATHGAYGCNAARMGNAAYYTNAAYATGYTNMGNYTNGGNAAR MGNAAYYTNAAYATGYTNMGNYTNGGNAARMGNCARYTNAAYATGYTNMGNYTNGGNAAR MGNCARYTNAAYATGYTNMGNYTNGGNAARMGNCARYTNAAYATGYTNMGNYTNGGNAAR MGN---------GTNGAYGARGCNTCNAARMGNAAYYTNAAYATGYTNMGNYTNGGNAAR MGNCCNGCNGAYTTY------GCNGAYAARMGNAAYYTNAAYATGYTNMGNYTNGGNAAR MGNCARGAYGCN------------AAYAARMGNAAYYTNAAYATGYTNMGNYTNGGNAAR MGNCARGAYGCNAAYAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATGGCNGAYYTNATHCAYAARATHTTYGGNCCNAAR CAYGGNAARGGNGGNTCNGARGGNAARCARTCNTCNGARCCNGARGGNTAYACNAARCAY CARCAYGARTTYTTYAARGARTTYYTNGCNTTYGAYMGNTAYAARCAYATHCAYAAYGCN ATGTAYTAYGAYYTNTGGATGACNACNAARAARGCNYTNTTYTTYATHGCNTCNGTNTGG ATHYTNTCNATHYTNATHTCNTTYYTNCCNATHCAYYTNGGNYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGARAGYCARCARAGYTTYYTNYTNGTNTTYYTNGGNACNYTNATHTGYGCNAGYYTN GTNACNTGYYTNCCNAARMGNTCNGCNGARGAYATHYTNCARGAYACNTCNGGNATGGTN YTNAAYAARMGNCCNAARTAYATGGAYACNMGNMGNGAYYTNGAYGTNTTYAARGAYYTN GTNYTNATGAGYGTNCARGARYTNGTNGAYGARGGNMGNYTNGARTCNTCNATHYTNCCN GARGAR------GAYMGNGARACNAGYCARCCNGTNGARAARMGNMGNTAYATGGGNYTN TGYATGCAYMGNCARGCNGAYCARTAYATHCCNTTYCCNTGYYTNMGNGCNGGNMGNATG AARGTNGTNYTNTGYYTNYTNYTNATGGGNTGYGCNGCNGTNATGGCNGAYAAYTAYYTN TGYCCNCCNTCNAAYGGNAARGARTTYGAYTGYTAYGARTAYGAYCCNGARTAYMGNGCN TGYYTNACNGAYGGNAARMGNGGNGAYGCNTAYGTNGTNTGYTCNAARTGYAARMGNAAR TGGGARTTYTGYGTNACNCAYGGNAARATHCARGARTCNAARAAYCCNGARMGNGAYTGY GGNGCNGAYTAYAARACNACNCCNTGYACNCCNGARAAYTCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ACNYTNATHATH ATHTCNTCNTAYACNGCNAAYYTNGCNGCNTTYYTNACNATHGARAARYTNGTNGCNCCN ATHAAYTCNGCNGAYGAYYTNGTNGAYCAYCCNACNATHAARTAYGGNACNAARAARACN GGNACNTCNTGGMGNTTYTTYCARCAYTCNACNATHGAYACNTAYATHAARATGMGNAAR GCNATGGARCARCAYGARGARGAYGTNYTNTTYACNACNTAYGAYGAYGGNGTNAARAAR GTNMGNGARTCNAARGGNGAYTAYGCNTTYYTNYTNGARTCNGCNATGAAYTCNTAYCAY GCNCARCARGARCCNTGYGAYACNATGATGGTNGGNGAYCCNYTNGAYAAYAARGGNTAY GGNGTNGCNACNTAYYTNAAYTAYCCNYTNMGNCAYAAYATHAAYATHGCNGTNYTNACN YTNGARGARAARGGNGARYTNATHAARYTNCARCARAARTGGTGGYTNGAYAARGGNCAR TGYGGNGCNCARAGYTCNGGNAARGARTCNACNGGNACNAARAAYGCNYTNACNYTNAGY AAYGTNGCNGGNATHTTYYTNYTNACNYTNTGYYTNTTYGCNGGNAGYACNTGYGCNGTN TTYTAYATHCCNGGNTCNGTNGTNAGYTAYCCNAARATGGGNAARMGNGCNTTYTAYACN AAYGCNACNGGNAAYMGNTAYCCNYTNATGGGNMGNMGNTCNTCNGGNACNAGYTCNGAR GCNCAYCAYGCNGAYAGYCCNAGYCARAAYGCNGARGTNGCNATGGCNGGNGCNATGGTN CARAAYAAYAARMGNGGNGTNTTYACNCARGGNCCNCAYMGNAGYTTYCCNMGNGTNGGN MGNAGYTCNGGNGCNAGYAGYGAYGCNTCNTCNTCNGTNGGNGGNAARATHMGNAGYGAR ATHYTNAARAGYYTNGCNGARMGNYTNAAYMGNAAYGTNYTNGARGTNYTNGGNGGNAGY AGYCARGAYAGYACNGARTCNYTNAAYYTNAAYGGNYTN---GARTTYYTNTTYYTNATH TTYGAYGARGAYGGNGAYGGNAARYTNAGYAARGARGARTTYACNTCNGGNATGGCNAAR GTNYTNGARCARAAYYTNYTNTGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AAYGGNGARTAYTTYTTYAARYTNTCNTCNMGNMGNATGMGNTCNAARGARGTNCAR GTNATHCCNTGGGTNGTNTCNGAYAGYAARTAYTCNTTYCARCCNACNCARMGNYTNGAY TCNAAYMGNACNGTNTTYGTNGGNGCNYTNCAYGGNATGYTNACNGCNGARGGNYTNGGN AAYATHATGGCNGAYYTNTTYGGNAAYGTNGTNGARGCNGGNATHGAYACNGAYAARCAY MGNTAYCCNATHGGNTCNGGNMGNGTNACNTTYAGYAGYMGNAARAGYTAYATGAARGCN ATHCARGCNGCNTTYATHGARATHAARACNAGYAARTTYACNAARAARYTNTGYMGNGAY YTNATGTGYTTYAARTAYTTYTGYMGNTCNTGYTGGTAYTGGCARCAYGCNCCNGARACN ATGMGNCAYCAYMGNACNYTNACNMGNAAYACNAARAGYACN------------------ ---------------------------------GCNGAYTAYGARCAYTAYTGYAAYCCN GAYTCNTTYAAYYTNCARCARAGYGGNGTNTGYGGNGAYGAYYTNGTNGAYYTNATHGGN YTNTAYTGYACNCAYTTYGCNGGN------------------AARTAYGTNGTNAARMGN AGYCCNAGYGAYATHGAYGCNCAR---GTNCAYGARYTNYTNGTNAAYAARAARGAYGCN TTYTCNTTYYTNTCNAARMGNCARAGYAARCARAAYATHGTNTGYGARTGYTGYGTNAAY CARTGYTCNCCNATGGARYTNYTNCARTAYTGYCARGTNCCN---MGNTAYACNCCNMGN TTYGTNGGNAARMGNTAYACNCCNMGNTTYGTNGGNAARMGNTAYACNCCNMGNTTYGTN GGNAARMGNTAYACNCCNMGNTTYGTNGGNAARMGNTAYAARCCNMGNTTYGTNGGNAAR MGNTAYAARCCNMGNTTYGTNGGNAARMGNGCNGCNCCNCAYTCNATHCARAARMGNCAR GCNCCNMGNTTYGTNGGNAARMGNGARGCNATHTAYGARCCNTTYGGNGTNGCNTCNTGG ATGGCN------------GGNGGNAGYGAYGARGGNGAYATGGTNGAYAAYGGNGAYGAR TAYTTYYTNGARGARGAYAGYGAYGAYAARMGNGAYTGYTCNGAYAAYGGNGTNGAYAAR MGNGGNCCNCCNMGNTTYGTNGGNAARMGNGCNAAYCCNMGNTTYGTNGGNAARMGNGGN CCNCCNMGNTTYGTNGGNAARMGNGGNGTNCCNMGNTTYGTNGGNAARMGNGGNCCNCCN MGNTTYGTNGGNAARMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GGN---TGGATHYTN TGYAAYACNGARCARAAYGGNTTYTAYMGNGTNAAYTAYCARGTNGGNAAYTGGAAYGCN YTNATHCAYCARYTNGARACNAAYCAYYTNGTNATHGAYACNATHAAYMGNGCNCARATH ATHAAYGAYGCNTGGAAYYTNGCNAARCCNAAYYTNYTNGAYATHGARATHGCNYTNAAY ACNGTNACNTAYYTNAAYAARGARYTNGCNTAYATHCCNTGGGCNGCNGCNATHAGYGAR YTNTCNTTYGTNCARMGNATGGTNTCNYTNACNTCNACNAAYGGNATGTTYCARAARTTY ATGATHGAYAARGTNACNCCNTTYGCNTAYTAYACNYTNAAYAAYGCNGGNGCNACNCAY GTNGARACNGAYTCNMGNMGNMGNATHGCNTCNACNGCNTGYTCNTAYGGNATHAARGCN TGYACNGAYGARGCNAARAAYCARTAYAARGCNTGGATGGAYGARAAYAAYATGATHGAY CCNAAYYTNAARTCNACNATHTAYTGYACNGCNATHAGYCAYGGNGGNTGGGAYGARTGG AARTTYGCNYTNGAYMGNTAYAARGARTCNCARATHGCNTCNGARAARGCNATHYTNYTN TAYGCNATGTCNTGYTCNTCNAARCARTGGATHYTNGCNCAYTAYYTNAARYTNATHATH GARGARGAYTCNATHMGNAAYCARGAYGCNYTNTCNGTNATHGGNAAYATHGGNTCNAGY ACNACNGGNMGNGCNYTNACNTGGCARTTYTAYMGNGARAAYTTYGAYCAYYTNAGYGAR TAYTTYTCNGARTCNTTYTTYTCNTGGGGNMGNYTNATHGGNGARYTNACNMGNTCNTTY AAYACNGARTTYCARYTNTCNGARYTNGAYTTYATGAAYAARAARAAYGAYAARYTNGGN GCNAARMGNGCNTTYGARCARGCNATHGARACNGTNMGNAGYAAYATHAARTGGATGGAR AARAGYTAYCCNACNGTNCAYMGNTGGTTYATGACNACNMGNGGNACNTCNAGYATHTCN CCNCCNGTNCARATHCCNCARCCNMGNCAYGTNTCNACNATHTCNTCNGGNACNCCNCCN CCNAAYCARCARATHTTYCCNGGNCARTCNCCNGGNYTNGTNCARGGNCCNACNTAYAAY TTYATHCARCCNCARTAYCARCARGGNGARCARTTYYTNCCNTAYCARGCNTAYGGNAGY GCNCCNAAYGAYYTNMGN---GGNACNTCNAAYACNGGNMGNGGNGGNACNGGNCCNGCN AAYATGGCNCARTCNGGNGCNTAYTAYCAYCARGCNAAYCARAAYATGMGNCCNTCNCAR ------CCNCCNCCNCCNAAYCARCCNTAYTAYYTNAAYCARACNGGNCARAAYAAYATG MGNCAYCCNMGNCCNAAYTCNGCNCCNAAYCCNCAYATGGTNTTYATHCARCCNAAYCCN AAYAAYATGGTNATHTCNAAYATGTAYCARCARACNCCNMGNATGCCNYTNTAYTCNCAR GGNGGNCCNCARTAYCARACNMGNTAYGCNCARCCNGGNGGNATGATGTAYTTYAAYGGN GTNTCNATGCARACNCARGGNATGGGN------CCNCCNCCNGCNCCNMGNGARAARMGN TTYATHAARATHAGYGAYCCNAAYACNGGNMGNAAYATHACNGAYGARATHATHAARTCN TCNCAYCARGCNCCNACNGAYGARMGNGGNGARTCNGARGAYACNTCNGCNAAYGAYAAR GGNGTNGARAARAAYTTYACNMGNCARGTNGTNGARMGNATGAARATHGGNGARTCNTCN GCNTCNCCNGCNCARCCNYTNGTNGARCCNGCN------AGYCCNTCNCCNCARCCNGGN GGNYTNTCNCARTCNAAYCARCCNAGYCARGARCAYGCNCARYTNCCNTCNTCNTAYCCN CCNGGNCAYCCNCARCARCCNCARTCNACNCCNCCNYTNGCNGGNGCNGGN------YTN GGNCCNATGYTNCCNCCNCCNATGGCNGTNCARATGGAYATGAGYGTNCCNCCNCCNTCN YTNCCNCCNAAYATG------------------------CAYGTNYTNCARCCNAARGGN CCNCCNTCNTCNGTNGCNATHACNGAYACNGCNCCNCCNCCNTCNYTNCARGAYACNCCN TCNACNGCNGARMGNAARACNTCNGCNTCNCAYATHGARGCNGTNATHCCNAARATHMGN CARACNCARCARTCNCCNCCNGCNTCNGAYCCN---GCNCCNCARCCNGTNGTNATHTCN ACNTCNTCNGAYACNAARCARYTNAARCCNGARGCNGCNAGYGARGCNGAYAAYGCNGTN AARGARACNGCNGCNGCNAARGCNGCNGAYGCNCCNAARAARACNGAYGARYTNAARGAY GARTAYGGNGCNGGNGCNAAYACNCARGGNAAYAARGAYGGNMGNAARAGYAARAARAAY AARAARGAYTTYAGYMGNAARGARAGYGGNGGNTCNGAYATGGAYGCNTTYATHGAYGGN AARGAYAGYYTNTCNGARAGYAARGCNCARATGCCNACNGTNTCNMGNCARACNGAYATH GAYYTNCCNCCNGTNCCNATHCCNYTNACNCAYGTNGAYGCNCCNGTNAARCCNGTNGAR GARCCNAGYCCNGCNACNGTNGTNAAYCCNGAYACNATHCARAAYGGNACNGARYTNGCN GAYAARYTNCARACNGARAARTCNAGYGTNCCNAAYGAYAGYCCNTCNGTNCCNGARGAR ATHYTNCCNGARGARAAYGGNACNGTNCCNTCNAAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GCNGARGTNTAYGCNAARYTNAARAAR---AGYGGNGGNAAR YTNGTNTAYGAYMGNGCNTAYYTNATGGARYTNMGNGARTGYGCNTCNTCNCARGCNAAR CCNGAYGGNYTNCCNGCNYTNGARATHATHYTNGAYCARCCNAGYCCNTTYATGTCNMGN TCNTCNATG---GGNCCNGCNGAYTTYACNCCNGCNTTYTTYCARACNGGNGTN---AAY CARMGNCAYGCNCCNCCNATHGGNAARAGYAGYAGYMGNGGNMGNCARMGNCCNGGNGAY ATGCCNGCNACNCCNMGNGTNATHAARAGYATHTCNATGTCNAAYGARGCNAAR---YTN CAYCARAGYGARAAYCCNTGGAAR---------CCNACNAARAARGARGAYAARGAYGAR CARAARAGYYTNGARGGNGARATHYTNTTYATHATGAAYMGNYTNACNCCNACNAAYTTY GARAARATGGCNAAYGARATGAARAAYYTNAAYGTNAARACNTAYGARGAYYTNCARTTY ATGGTNAARNNNTTYTTYGAYAARGTNACNYTNGARACNAARTTYGTNGARGCNTAYGCN CARYTNTGYAARGTNATGTCNGGNYTNAARGTNGCNCCNCCNGCNGAYGGNAGYGTNAAR GARAAYATGGCNACNTTYMGNGTNGTNATGYTNACNAARTGYCARCARGARTTYGARGCN GAYAARTCNATHATHTTYGARAAYCCNGARGAYAARMGNAARAARYTNGARGCNGARAAY CCNGARAARACNCCNGCNMGNGAYGARATGATHGARAAYACNYTNTAYCARATGAARYTN AARMGNATGAARTTYTAYGGNAAYATHMGNTTYATHGGNGARYTNTTYAARYTNGGNATG YTNACNGARAGYATHATGCAYGAYTGYATHTAYMGNYTNYTNAARGCNMGNGAYGAYGAY TCNYTNGTNTCNYTNTGYAAYYTNYTNACNACNGTNGGNMGNAAYYTNGAYACNGAYAAR GCNAARCCNMGNATGGARCARTAYTTYTCNCARATGACNAARATHGCNGAYGARMGNAAR TCNMGNATHAARTTYACNYTNMGNGAYGTNATHGARYTNMGNCARAAYAAYTGGATHCCN MGNAARCARTCNACNGGNCCNAARAARATHGAYGARGTNCAYAARGAYTTYGCNCARGAR CARATGMGNAAYCARTAYYTNGCNTCNCARCCNCCNCCNCCNMGNAAYGAYAAYTCNYTN GCNGGNAGYMGNMGNGGNAGYMGNCARMGNCCNGAYGARAAYAARATGGGNGARGAYGGN TGGAAYACNGTNGGNAAYCCNAARTCNTTYMGN---ATHGAYGCNTCNAARATGAARATH TCNTCNAARAGYATGGTNGAYGAYAAYATHCARYTNGGNCCNGGNGGNGGNGCNCAYAAR ---CCNATHTGGAGYMGNGGNAGYCAYGGNGGNACNCARCARCCNCCNCARGAYGAYMGN CCNGCN---YTNGGNAAYMGNTTYTCNGCNYTNACNAGYGAYGAYGCNMGNMGNTCNTTY CCNMGNTCNCCNTCNMGNGGNGARGGNTCNGCNGGNMGNGGNYTNMGNCARGGNCARACN GCNGGNCAYGGNMGNGGNAARATHYTNACNMGNTCNAGYCARGARGGNGARMGNMGNGAY GCNATHGCNAAYGCNMGNTCNTTYATGGGNGGNMGNTCNCARAAYTCNAGYMGNGAYAAY AGYTGGAAYMGNGAYGAYGGNMGNCARTTYATGGGNCCNMGNAGYTCNTGGGAYMGNGAY AAYCCNATGACNMGNAGYGAYAGYGCNGTNMGN---ACNGARGARTTYAARACNCCNGCN CCNCCN------TCNGTNAARCARATGACNGARAGYGARATHGARACNAARGCNGTNAAY ATHYTNGAYGARTAYYTNAAYATHMGNGAYYTNGCNGARGCNAARYTNTGYATGAARGAR YTNATHGGNCARAAYCAYYTNCAYYTNGTNGTNACNGCNAGYATHAAYCAYGTNYTNGAR AARMGNGAYGAYGAYMGNMGNATGACNGGNAGYYTNTTYAAYGARYTNGTNAARCARAAY ACNATHTCNGTNAGYACNTTYGTNAARGGNYTNAAYGARGTNYTNGARTTYGCNAGYGAY ATGGTNGTNGAYATHCCNACNYTNTGGAAYTGYYTNGCNCARGCNATHTCNCCNYTNYTN GTNGGNGGNTCNYTNCCNTGGTCNAARYTNAARCARGTNTTYACNCCNCAYYTNGAYAAY AARGAYGGNGCNAARYTNATGGCNGCNYTNYTNTCNCAYTCNGTNGARAARYTNGGNGAR AARGARATHTCNCARGARTGGCARAAYAGYGGNYTNAGYTGGTCNACNTAYYTNAARGCN GARGARYTNAAYACNTTYGTNGCNGAYAARAARYTNAGYTTY---ACNYTNGGNGCNTCN TCNGGNGGNGCNGCNYTNYTNCCN------------------------------------ GAYYTNGARAARATGATHMGNAAYMGNGCNTCNAAYAAYGARYTNYTNTCNTAYATHGAR AARACNGTNCCNGGNAGYAARAARGAYTCNAGYTTYATHMGNTCNYTNACNACNGCNGTN GTNAGYTCNTCNATHAAYGARAGYAARAGY---------ATHAAYGARGAYGTNATHAAR AGYAAYAARGAYGTNYTNCARMGNTAYYTNGGNAAYTCNGTN---GAYYTNCARYTNCAR GCNYTNTAYGCNATHCARTCNYTNATGGTNAARYTNGARCAYCCNTCNGGNGTNYTNGCN AARYTNYTNGARYTNYTNTAYGAYGARATGTCNYTNGARGARGARGCNTTYTAYMGNTGG GARAARTGYAAYGAYCCNCARGARCARGARGGNAARGGNACNTGYYTNATGCARGTNMGN CARTTYTTYGTNTGGYTNMGNGARAAYGARGARCCNGAYACNGARTCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GGNGAYCCNYTNGGNGAYGAYAGYATGGARGCNTTYATHAAYYTN GAYAARTTYYTNAAYGGNAAYTCNTTYTTYGAYGAR------GAYGGNAAYYTNACNGTN GTNAGYGARGARGCNGARGTNACNCCNGTNATHAAYYTNAGYGARGARGARACNACNAAR GTNTCNGTNCARCAYAAYAARCARAARCCN------------------------------ ------TCNMGNAARMGNAARGCNGCNGCNGCNGCNGCNGGNGTNAARACNAGYYTNTAY GARATHCCNGCNACNTCNYTNATHCCNGARATHCARGTNGARGGNAGY------ACNACN ACNYTNTCNGAYACNGARYTNGAYCAYGAYTAYAGYTCNAARAARMGNCARMGNYTNGAY ATHCCNGAYGGNAAYGAR------------AGYACNCCNTCNACNAGYGGNGCNATGMGN AAYYTNATHCARACNGGNGTNCCNCARACNGTNATHACNTCNGCNGCNTCNGCNTCNYTN ATHCCNGTNCARYTNYTNGAYGARACNGTNGAYAARCARACNATHMGNMGNATHAARAAY AAYCAYGCNTCNAARMGNTCNMGNGARCARMGNAARCARAARTTYGTNGARATGGAYCAR GARGCNGARGARYTNGTNGTNMGNAAYCARCARYTNMGNGARAARATHGTNGARYTNGAR ATGYTNGCNAARGARATGAARGCNGTNYTNGTNGCNAARATGGCNGGNAARGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGGCNGAYAAYGCNGTNGAYTCNACNAARAAYGARGARGAYGGNACNGAY TCNGCNGAYTCNAARGTNTCNTCNTCNTTYGGNGGNMGNGCNMGNCCNTTYTCNGAYTCN GTNCCNTCN------TCNGCNCARGAYGGNAAYCARGARGTNAGY---AGYTCNGAYATH ACNGARTCNGGNTGYATGTCNCAYCCNCCNAARGTNGGNACNTCNATGAGYTCNTAYAGY AAYGCN------TTYGGNAAYACNCAYAAYGCNGGNATGTAYACNAAYCCNTTYGTNCCN MGNGCNCCNYTNAARTCNGAYGTNGTNTCNACNGAYCARTCNAAYAGYAAYGAYAGYMGN GARGGNYTNATHGCNCCNAGYMGNYTNAAYGCNGCNGTNAAYMGNGAYAAYTCNGARGTN GARGGNAAYMGN------TCNTTYYTNAARCARTCNGTNYTNGCNCCNCCNAARYTNACN GGNGCNGTNTTYGGNGGNGCNAGYGCNAGYCAYGAYACNCCNAGYTCNACNTTYAAYTCN TTYAAYTCNTAY---ATHMGNCCNTCNGTNTTYTCNGGNCCNTCNCCNGGNYTNGGNMGN GGNGGNGGNGCNCCNYTNYTNAARCCNGCNAARYTNCCNGAYCCNACNAARTCNTGYGAY AGYAARGCNGAYTCNGCNAGYGARGCNGARGTNAAYGTN---------CAYGCNAARTCN GGNGARGCNTCNTCNGCNAGYGAYMGNYTNGGNGGNGCNGAYGGNACNTCNGGNGGNAGY GARGTNTCNTCNTCNTCNGCNTCNTCNTCNCARYTNCCNCCNACNYTNTCNACNCCNTCN GAYGGNGARGGNGCNATGGGNGGNGARACNACNCCNTAYAAYMGNGAYATHGTNCCNGAY ATHAAYAARAAYAAYMGNYTNAARGAYACNTCNGGNGTNACNAGYAGYTCNCARTCNTTY GTNTTYGGNAGYAAYYTNTCNCARMGNGTNACNGGNATHYTNTCNTCNACNGAR------ AAYGARGCNTCNGCNTCNTCNGGNTTYGTNTTYGGNGARTCNYTNAGYTCNMGNGCNGTN GTNGARACNAAYGGNTCNACNCARCCNAAYAARGAYGAYGARAGYGAYTCNGAYTCNGGN GCNMGNYTNAAYMGNACNYTNGARGARTCNGCNMGNGARTAYCARGCNAARCAYGARAAY AARACNGARYTNAARGARGTNGARACNATHACNGGNGARGARGARGARTCNAAYGTNYTN CARGCNAAYGCNAARYTNTTYTTYTTYGARACNAGYAAYGARTCNTGGGTNGARMGNGGN MGNGGNACNATHMGNYTNAAYGAYATGTCNGCNMGNGAYAAYACNAAYTTYCARTCNMGN YTNGTNATGMGNACNCARGGNAGYYTNMGNGTNGTNYTNAAYGCNAARATHTGGCCNGGN ATGTCNGTNGARMGNGCNTCNACNMGNTCNATHMGNATHACNGCNATGGAYACNGAYGAR TCNATHAARATHTTYYTNATHACNACNAAYGTNAARGAYTCNGARAAYYTNYTNMGNGCN ATHGAYTGGMGNATHCARCARYTNAARATHCARGARGARCCNATGMGNCARCAYTCNGAY TCNMGNGTNGGNGAYAARMGNAARGCNGAYGAYTCNGAYTTYGARYTNCCNGTNAARAAY AARAARGTNAAYTGYTCNCCNGAYCARGGNATHTCNATHACNAARAARGARGARTCNGAY AGYAGYGTNCARGAYCCNGARACNGARGCNTCNTGYGARAGYCAYTCNTCNTCNYTNACN ATHAARTCNGARTCNGAYTTYCARTGYATHCAYTGYGGNTGYAAYACNGARAARYTNTAY CAYGAYTAYAARGCNGGNATHACNAARGTNACNAGYTGYAARGCNTGYGGNAAYATHGCN GAYAARTAYGTNGARTAYGAYTCNGCNATHATHYTNYTNGAYGTNYTNYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNAARCARGGNTCNGTNATH GARTTYYTNTCNGCNGARGGNTGYTCNGCNGCNAAYATHCAYGCNMGNGCNAARACNGTN TAYGGN---GCNTGYNNNGAY---TCNGGNGTNMGNAARTGGYTNMGNATHTTYAARGGN GARGAYCCNMGNGGNACNATHGTNMGNGAYMGNNNNMGNTCNGGNMGNATGGCNTCNTCN AAYGCNTCNMGNACNGTNATHAARTCNYTNAARGGNMGNACNTTY---TCNGCNGCNGCN GCNCARGCNCAR---MGNGCNCAYATHGAYAAYGCNCCNAARTGYTCNATHAARCARYTN AGYAAYAARATGGCNGTNGGNGTNGTNCCNTCNAAYTCNCCNATHTCNMGNATHGCNGTN GTNGCNAAYGCNGGNTCNMGNTTYGARAAYGGNGAYAAYCARGGNGTNTCNCAYTTYYTN MGNATGTCNGCNMGNATGMGNACNGARAAYATGACNAGYYTNGGNATHACNMGNACNGTN CARCARYTNGGNGGNGAYGTNACNATHATGGGNACNMGNGARTAYATHTAYTTYAARAGY AGYGTNACNMGNAAYTGYGCNGARAARGCNGTNAARATHYTNGARGARYTNACNACNAAR CARGCNTAYATHGGNTGGGARATGGCNGAYATHCARAARGAYAARAAYGGNATGGCNYTN GAYYTNGCNYTNTAYGARACNCARCCNCAYGTNCAYGCNYTNGARYTNYTNCAYTCNGCN GCNTTYMGNAAYACNYTNGGNAAYTCNYTNTAYGCNCCNGARCAYGCNATHGGNAARTTY ACNCCNGARCARGTNATGCARTAYGTNAARACNCAYTTYAGYGGNGGNMGNYTNGCNYTN GTNGGNATHGGNGTNGAYGARGAYYTNYTNGARAGYYTNGCNAGYGCNTTYGARCCNTAY GCNTCNGCNGGNGTNCCNGTNGARAARGCNACNTAYCAY---GGNGGNGARYTNMGNGAR GGNTCNGGNGGNGAYGTNTCNTAYGTNGCNGTNGGNTTYGGNGGNCCNAGYYTNACNAGY AARGAYYTNYTNGCNTCNGARGTNYTNMGNCAYATHYTNGGNACNGGNCCNCAYATHAAR TAYAGYAGYGGNACNGTNGGNGCNGCNYTNGCNAARGCNGCNGCNGGNGCNACNGAYGCN CCNTTYCAYGTNTCNGCNYTNAAYGCNAAYTAYAGYGAYAAYGGNYTNTTYGGNTTYACN GCNGTNTCNCAYGCNACNCARATHGARAARGTNYTNCARGCNGCNGGNAAYCARTTYAAR GGNGTNYTNTCNGGNAAYATHACNGAYCARGAYGTNACNAARGCNAARAAYCARYTNAAR GCNGARATHTGYATGCARTTYGARAAYCCNGAYATHYTNYTNAAYTGGYTNGGNGARCAR GCNYTNAAYAGYGARCARYTNATHACNCCNGARGAYATHTAYAARATGGTNGAYAAYATH AAYACNAAYGAYGTNAARACNGTNGCNAARAGYATHATHGGNTCNMGNCCNAGYATHGCN TCNGTNGGNAAYGTNGCNAAYGTNCCNTAYYTNGAYAARYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AARAARATHCCN AARYTNGCNCARACNGTNAAYAARGCNMGNGGNATHYTNAGYTTY------TCNAARGAR AARGARGGNTCNCARAGYYTNAAYGARGARAGYTCNCCNGCNACNCCNTCNGAYACNGCN GARACNGGNGCNGCN---------GAYGGNTCNTCNGCNGARACNGGNGAR------GCN CCNGCNCARGARTCNGCNCCNTCNACNGTNMGNACNGARTTYAARTGGGARAAYGGNGGN GARACNGTNYTNGTNAGYGGNACNTTYAAYAGYTGGCARGARAAYGTNGCNYTNGCNAAR GARGGNGAYATHTTYACNGGNTTYATGGAYYTNCCNACNGGNGARTAYYTNTGYAARTTY ATHGTNGAYGARCARTGGGTNGTNAAYAARAAYYTNCCNATHMGNTCNGGNGARGAYGGN CARGARAAYAAYGTNATHYTNGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNATGGTNATGATHYTNTTYTGGTAYAGYATHCCNCARGTNTAYYTNTGGTAY ATHGAYACNAAYGAYAARCCNYTNYTNTGGACNTTYTTYYTNGTNTGYCAYTTYGTNGGN TGGYTNYTNATHGGNYTNGARGTNATGYTNATGGAYGTNGGNGARYTNYTNGGNTTYACN CARGTNTAYAAYTAYCAYAAYACNYTNACNCCNCCNYTNYTNAGYACNAARTTYGCNAAR YTNMGNGARATHTAYTCNMGNATGMGNCAYCCNGGNGTNGTNYTNYTNTCNGTNYTNYTN TGGTTYTAYCCNYTNATGACNYTNGAYMGNGTNYTNYTNGCNTCNGTNTTYACNGCNTAY ATGGTNTGGMGNCAYCARTTYGARGAYACNCAYTGYCARTAYGCNMGNAARMGNTTYTAY YTNTCNTCNGTNGARMGNAARTCNAGYACNGCNGTNTCNTAYGARTAYGTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGGGAYTAY ACNAARGTNGCNATGTGGATHGCNCAYATHGGNATGAGYCARTAYGCNAGYYTNTTYATG GAYTTYMGNGTNGAYGGNGTNCAYYTNYTNACNATGGAYAGYYTNAARATGGARMGNATG GGNATHMGNGAYGGNCARCAYACNATGTTYATGGARCARMGNATHMGNCARYTNAAYGAY TCNAARMGNYTNTCNGTNTGYCARACNGARATHYTNCCNCAYGCNTAYTAYMGNTCNYTN AAYYTNGGNCARGARCCNCCNTCNMGNTAYYTNGGNGARYTNYTNCAYTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNACNAGYCAYTGYCAYAARCARGGNCAYAAYCARGAR TTYMGNYTNAAYATGAARGGNCARATGGGNGTNGGNGARMGNTGYATHYTNGCNCARAAY GCNGAYTCNYTNCAYGTNAGYTAYTGYGCNGTNGARCCNGTNGGNCCNTGGGAYTGGGAY GARAAYACNGGNYTNATHAARCAYMGNGARYTNAARAARTGYGTNAARGCNGGNTCNGAY TCNYTNYTNCAYYTNCARTTYTGYGAYAARAARGAYCARGAYATGCARTGGGTNATHAAY GARGTNTAYCCNTGGAARTGGMGNAAYAARTGYGGNAARYTNGARAARGTNATHAARACN YTNTCNAAYCAYTGYGTNMGNGTNGTNGARCAYCAYGARGAYYTNYTNGTNAARTTYAAR AARAAYCARGAYCARTTYGARAARYTNAARGARAARTGYAARGARMGNGGNGARCARATH AARCARGCNMGNGCNGTNYTNATHCCNGTNTCNAAYGARYTNAARYTNYTNMGNGARAAR TAYGAYGTNGCNGTNMGNTGYCARATGGARGCNGARTCNTTYGCNATHCARACNACNAAY AARAAYAARAARYTNAARMGNCARAGYYTNGCNYTNACNGCNAARYTNTCNAGYGTNAAY ATHGTNGAYATHAAYATHGAYGAYGAYAAYGGNGAYGAYGGNGARGARAARAARTAYATH GAYTCNYTNGCNCARMGNATHGARGAYYTNGARGARGARMGNAGYGCNYTNAAYATHCAR YTNAARGAYGTNACNGAYAAYYTNCARGAYCARCARGGNTCNAAYCARMGNYTNAARGAR MGNATGGARAGYYTNMGNGARGARYTNMGNCARGCNAARGCNACNGTNCARGAYCARGAR GTNYTNYTNCAYAARGTNGCNGTNACNTCNGARATGGCNTTYCARGARTAYCARGAYYTN GARCARACNTGYMGNAARGARGTNYTNGTNMGNAAYGARGCNGARMGNTTYGCNCARMGN YTNTGYACNGARMGNGAYCARGCNMGNMGNGARAGYGCNGTNGCNYTNAGYAARGTNGCN GAYAAYAARAARYTNATGGAYGCNATGYTNGARATHCARGARYTNAAYGCNCARACNGCN CARATHAARGAYGAYTTYCAYAARCARATHGCNGCNYTNGARGARCARYTNMGNGCNGCN MGNGARGTNTAYGAYGCNAAYGCNYTNGGNGCNGARAAYCARGARYTNGCNGARGARMGN ACNGCNYTNCARCARAARYTNGAYGCNAGYCARGCNGARGTNGCNGARYTNMGNGCNAAR TAYGCNCARYTNCARGARACNTAYAARACNYTNCAYGAYAAR---------ACNATGTAY GTNCCNCCNCCNCCNCCNCCNCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNGAYMGNGARMGNGAYMGNYTNGAYMGN GAYMGNGARMGNGAYMGNGAYMGNGAYMGNGAYMGNGCNACNMGNAARATHGGNAGYGGN ACNATHGCNATHGAYMGNGAYGGNGGNMGNGAYTTYTCNAGYYTNMGNGAYMGNGAYMGN GAYGARMGNGAYTCNGAYMGNGAYMGNGARGTNCCNTGGGGNMGNGAYMGNATGGAYMGN AAYMGNGAYMGNGAYTGGGAYMGNGARMGNGAYMGNGAYMGNGAYGAYTGGGAYMGNGAY MGNGAYMGNMGNTTYGAYMGNMGNTCNGAYMGNTTYMGNMGNGAYAGYGAYMGNGAYTAY ATGGAYMGNAAYGAYMGNGAYMGNMGNGAYMGNGAYMGNTCNTAYGAYMGNCCNGGNMGN MGNMGNAAYATHTCNGARGAYGAYGARCCNGARTGGTTYACNGGNGGNCCNACNAGYCAR ACNGAYACNATHGARYTNAARGGNTTYGAYAGYGARAGYCARAARCAYCCNAAYGGNYTN MGNYTNAARAARCAYGAYYTNGARAAYGGNGTNGGNAAYGGNAGYTCNMGNATHAARGCN GARTCNGARAARGARMGNGTNAARATHGARCARTCNAARGAYGAYGAYGTNTTYGTNAGY GCNAAYGARGCNMGNGGNCARCARGARTCNGARAAYCARGARGARCARYTNYTNMGNAAY GAYCCNGCNCAYTCNGCNGARAAYCARAGYTTYGAYYTNGAYGARTTYYTNAARACNAAY YTNAAYYTNAAYGAYGARGCNGARTCNCARGGNAGYMGNTTYTCNMGNTTYTTYGGNTCN GGNAAYGTNCCNGCNTCNTCNATGACNGARGAYATGATGCCNMGNGAYYTNYTNGAYGAY AGYMGNTCNAGYCCNGTNATHCCNTCNCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNTCNGCNAGYAAYGTNAARGARMGNTCNMGNGCN TCNACNATGTCNTCNGGNGGNGGNAGYGCNYTNGARGARGGNTCNYTNCCNAGYATHCAR TCNGCNACNAGYTCNGTNGTNTCNAAYGCNAGYAARTCNTAYCCNGARYTNTCNGCNGAY GTNGARGCNTCNYTNCCNACNAARGGNAAYMGNAARCAYTCNGARMGNAARAAYTCNMGN CARAGYCCNAAYACNTCNMGNGTNCCNACNCCNACNAAYACNGCNGARACNYTNGTNTTY ACNATHGAYACNATGCARAGYTAYYTNAAYAAYAGYCARGGNAAYGGNACNTAYYTNCCN CARACNGTNTTYYTNGARACNTCNACNTGYCARTAYTCNCCNCAYAAYGTNCAYACNGCN CARATHYTNCCNGGNGTNACNYTNGTNYTNYTNTCNCARGCNCCNMGNCAYGTNYTNGCN GAYCCNYTNTAYCARGTNATGAGYAAYATHCARGAYYTNATHTTYGGNMGNMGNATHAAR YTNCCNMGNTCNMGNAGYYTNCAYGTNTAYGARATHATHAAYTCNYTNYTNGGNAARYTN CAYAAYAGYYTNMGNAARTTYAARGGNMGNGARMGNACNYTNATHTCNGAYATHCAYYTN MGNTGGGARAARGARGAYGTNAARCAYMGNYTNYTNGARTAYYTNGARMGNGAYTCNMGN TAYCARATHCCNCCNGAYGTNGARTCNCCNYTNGTNGARATGTTYAARAARYTNMGNGAR YTNTTYTCNYTNYTNTTYYTNTGYCCNYTNCCNGAYAAYCCNCARYTNTGGGARTCNATH TCNCAYYTNMGNGTNGCNATHAAYGCNGARYTNYTNGAYTAYMGNGARTAYYTNAAYGTN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ACNAARATGAARMGN TCNGARMGNCAYATGATGMGNYTNAARAGYATHATHGCNAARGTNYTNATGGARAARGGN GTNGGNAARGAYGAYCCNATHTAYGARGCNTGYTCNAARAAYYTNYTNAAYGTNAGYGTN GTNYTNYTNAARAGYYTNCCNAAYTCNYTNAAYYTNACNGAYGARATGAARTCNGTNGTN TAYAGYCARGTNCARCARATHATHAAYYTNGARAARMGNMGNTCNGGNATHGCNYTNGAY GGNTTYGCNTAYGTNACNTTYAARGAYMGNAARCCNGTNATHGTNGCNAARATHGCNGAY TCNYTNAGYMGNAAYMGNGARCCNYTNAAYGARMGNTAYAARGGNGCNGAYTCNGAYATH CARYTNAARAGYATHATHGGNGCNATGTCNTGYYTNMGNCAYGARATHATGACNAAYAAR CCNGCNGTNCCNYTNAARGAYACNGGNCCNGAYGCNATHGCNTGGAAYCARGARYTNGAR GTNCARYTNAAYGGNGGNCARCCNYTNAARTGGTTYGAYCAYTCNTGGYTNTGGATGGAR TGYTAYYTNTAYMGNMGNGTNCAYGARGCNGTNYTNATGAGYTCNTGYTTYMGNTCNYTN GAYGTNTTYGARGARCARAARCARAAYGCNTTYACNGGNTCNTAYGARTCNATHTCNGCN ATHATGGTNTAYYTNTAYGARYTNGTNAARATGATGTCNYTNTGGGGNAAYAARTGYGAY YTNTCNYTNTCNGCNGGNCARGAYAAYAAYGCNACNGARAAYCCNGTNCAYCARYTNGAR MGNYTNATGCCNAAYATHYTNATHAAYGAYTCNCAYCAYGTNYTNAARYTNYTNMGNGAY AARCARAARAGY---GGNGGNGGNGGNGCNAARATHTCNTTYGTNYTNGAYAAYGCNGGN TTYGARTTYATGACNGAYYTNTGYYTNGCNGARTTYYTNYTNTCNAGYGGNYTNGCNTCN TGYATHGARTTYCAYGGNAARGCNTTYCCNTGGTAYGTNTCNGAYGTNACNGARGCNGAY ACNGAYTGGGTNTTYMGNCARATHTCNATGATGGAYCAYGTNGCNATGAARGARYTNAGY CARATHTGGMGNAARMGNGTNCARGAYGGNACNATGACNTTYCARTAYCAYCCNTTYTGG ACNACNCCNCAYCCNTTYTAYAARATGGARACNYTNTGYCCNGAYYTNTAYTCNAARYTN AGYCARAGYGAYYTNGCNATHTTYAARGGNGAYYTNAAYTAYMGNAARYTNGTNTCNGAY YTNATGTGGGAYCCNACNACNMGNTTYGCNACNAGYYTNMGNGGNTTYCARCCNACNTCN ATHTGYTCNYTNMGNACNGTNAARGCNGAYGTNGTNGTNGGNYTNGARGCNGGNCARGCN GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------TCNTTY ATHCCNTGGCCNMGNCAYAARTGYYTNTAYGGNMGNAAYGGNCAYATHGAYGARACNYTN ATGAAYAGYATHYTNGARGGNAGYGAYGARMGNGTNGTNGGNTGGTAYAGYTTYMGNTAY CARACNAGYCARATGGCNTCNATGAARGARTTYTCNATHCAYAGYGARYTNACNCARAAR TGYGTNAARCCNGARGARTTYGTNTTYYTNYTNTGYACNTCNYTNGCNAAYMGNAAYYTN TCNACNCAYTCNTCNGAYCAYACNTTYATGGTNTGYMGNAGYGGNMGNTTYGCNCAYATH CCNATGACNGTNAARAAYYTNGGNGAYACNTCNAARATGGARTAYATHGTNGARAAYTCN TCNCCNGCNACNTCNAARGTNATHAAYGCNAAYATGGGNAAYTCNGGNAARAAYTTYGTN GTNGCNTCNGGNCARGTNAARCARGTNGCNGAYATGAARCAYYTNATHTCNTCNATGACN AARGGNYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYCAYNNNMGNAARNNNNNNNNNNNNNNN MGNAGYMGNAGYMGNGARMGNAARMGNTCNMGNAGYMGNGARMGNAARTCNMGNAGYMGN AGYMGNGAYMGNMGNMGNAARGAYGAYGTNGARAARGGNMGN---MGNMGNAGYMGNAGY MGNAGYMGNGARMGNMGNMGN---MGNAGYMGNAGYMGNAGYMGNMGNMGNMGNAAYAGY MGNAGYMGNAGYMGNGAYMGNMGNMGNMGNAGYMGNTCNCCNMGNMGNMGNTAYAGYMGN AGY---------MGNGARMGNYTNCCNGARYTNACNGTNGARGARMGNGAYGTNMGNACN ATHTTYTGYATGCARYTNTCNGCNMGNATHMGNCCNAARGAYYTNGARGARTTYTTYTCN TCNGTNGGNAARGTNMGNGAYGTNMGNYTNATHACNGAYAAYAARACNMGNMGNTCNAAR GGNATHGCNTAYGTNGARTTYGCNGAYCCNGARTCNGTNACNYTNGCNATGGGNYTNACN GGNCARAARYTNYTNAGYGTNCCNATHATHGTNCARCCNTCNCARGCNGARAARAAYMGN GCNYTNCCNGCNACN---GCNCCNGCNCARAARCAR---GCNCCNGARGGNCCNYTNMGN YTNTAYGTNGGNTCNYTNCAYTTYAAYATHAAYGARGAYATGYTNMGNGGNATHTTYGAR CCNTTYGGNAARATHGTNGAYATHAARATHATGMGNGAYCAYGAYACNCARMGNTCNYTN GGNTTYGGNTTYATHAGYTTYGCNAAYGCNGAYGAYGCNAARAARGCNYTNGAYCARYTN AAYGGNTTYGARYTNGCNGGNMGNCCNATGAARGTNGGNCAYGTNACNGARMGNACNGGN GARCARGGNCARGGN------GCNCARAAYGGNGTNGGNGGNCARYTNGAYACNGAYGAR ATGGAYMGNGCNGGNATHGAYYTNGGNGCNACNGGNMGNYTNCARYTNATGGCNAARYTN GCNGARGGNACNGGNTTYCARATHCCNCARTAYGCNGCNAGYGCNYTNAAYAAYATGACN CCNGCNGCNGCNCCNGGNGTNCCNGTNACNGTNGCNCCNGCNGCNCCNGTNGCNAAYACN ATGACNATGCCNCCNGTNYTNCCNCCNACNACNATGGCNGCNCARCCNCCNCCNGCNACN GCNGCN---------GCNCCNCCNATHGCNACNCARTGYTTYATGYTNTCNAAYATGTTY GAYCCNACNTCNGARCCNMGNYTNACNTGGGAYCARGARGTNMGNGAYGAYGTNATHGAY GARTGYAAYAARCAYGGNGGNGTNYTNCAYATHTAYGTNGAYAARAAYTCNCCNGARGGN AAYGTNTAYGTNAARTGYCCNAGYATHTCNGCNGCNGTNGCNTCNGTNAAYTCNYTNCAY GGNMGNTAYTTYGCNGGNMGNGTNATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYATGTTYTGGTAYYTNTTYYTNGAYAARTTYCARCCNAGY CARAAYTAYCARTCNAARYTNTTYAAYMGNGTNTCNCAYAAYTAYGTNAARYTNATGATG ATGACNGCNGAYCCNATHGCNAARGAYACNTTYTTYAARGAYTAYCCNAARYTNATGTCN CARGCNGTNTAYGCNTCNTTYTGYTTYTGYTTYCCNGAYTCNTAYMGNCARTTYGGNGAR AAYTTYAARGAYCARYTNGTNTAYYTNGTNTAYGGNTGGATGGCNGGNATHMGNCCNGCN CCNMGNACNTGGATHACNTGGGAYGTNACNCAYYTNGARCCNCCNAAYYTNAARATGMGN GARGARATGATGCARAARAARAAYAGYAARAARATGACNTCNTTYATHGAYTTYGAYTAY YTNGAYTCNYTNATHTCNACNAAYGCNAGYCARTAYGCNTCNACNATGTCNYTNGCNCAR TCNACNTCNAARTCNTCNACNACNTCNAAYYTNGGNCCNGCN---MGNAARCCNMGNATG CAYGCNMGNATHAGYAAR---CARCAYAARCCNYTNTTYMGNACNTCNTCNCCNAAYAAR ACNCAYTCNCCNAAYTCNTTYCARGAYTCNAAYYTNATHGAYGTNGTNGCNGAYGCNCAR GCNAGYCCNMGNGTNMGNGGNAARGAYGGNAAR---MGNGGNAGYGAYGCNYTNACNCCN GCNAARGAYYTNAARMGNCARAGYGAYGCNYTNACNCCNATHMGNGARATGAAYAGYGAR GAYGARGARGARGAYTTYGGNAARAARTTYTCNCARGTNTCNATGAGYCARATHMGNGAR AGYMGNAAYAARMGNCARTAYGTNATGGARTCNCAYCCNATGGGNMGNGGNTGYGARTTY GTNMGNACNGCNTTYAAYGTNGARGGNMGNAGYCCNYTNGTNGCNCAYTTYYTNAAYATG AARGGNYTNACNCARGAYGTNGGNCARAAYATHTGGATHCARMGNGTNGARGTNGAYGAR YTNCCNCCNYTNGAYGCNACNACNTAYMGNGAYGTNGTNAGYGARTCNTCNAARACNATH AARAARYTNGARTCNGGNTTYCARGAYYTNTAYYTNAARAAYTAYAARCAYAGYCARYTN TTYATGMGNAARCARCARAARATGYTNMGNGARCAYATGCAYAARCARGCNGCNYTNYTN GCNAAYAARGARGAYGTNAARGTNYTNTGYGAYYTNATHATHYTNGARCARMGNAARAGY CARGAYTCNGTNTCNGCNGGNGCNTCNGCNGCNATHGARGCNGCNYTNATGGCNCARGAR ATHCCNGARGARGARAARATHTTYCCNATHGAYTTYATHTCNGARGTNGARAARCARGTN CAYTCNGAYTTYTTYGAYGGNMGNCCNCCNAARACNCCNGARMGNTAYYTNAARATHMGN AGYTAYATHGTNGAYTGYTGGGTNAARAAYAARCCNACNTAYYTNAAYAARACNTCNGTN MGNCCNGGNYTNAARAAYTGYGGNGAYGTNAAYTGYATHGGNMGNATHCAYGCNTAYYTN GARTGYGTNGGNGCNATHAAYTTYGGNTGYGARCARGCNGCNTAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CCNGARYTNCCNTGYYTN ACNGAYTCNTGGGCNYTNCCNATHAAYCAYYTNTGGCARTTYTCNAAYTGGGAYGGNGAY CAYGTNAARAARTTYAAYMGNYTNATGGCNTTYMGNAGYCCNCAYTGYTCNGTNTGYTCN YTNTTYAAYAARTTYGAYCCNGARGARGARTGGTCNGTNYTNCARGCN---------MGN ATGGAYGGNGGNTCNATHCCNYTNMGNTCNYTNCCNGTNATHCCNGARTCNTCNTTYGCN GTNAGYGCNTCNAAYMGNACNCCNTTYTGYGAYTAYTCNCCNYTNGAYGARGAYGGNYTN AGYTCNYTNYTNGTNTGYTCNTCNTGYAAYGTNTGYGTNCAYGCNAGYTGYTAYGGNGAR TTYMGNMGNATHAAYTCNCARGAYTGGATGTGYGAYGTNTGYGTNTCNTCNTCNAGYGGN GAYGAYCAYGARTGYTCNYTNTGYTAYYTNMGNGGNGGNGCNYTNAARCARACNTCNGAY GGNAAYTGGGCNCAYGTNGCNTGYGCNYTNGCNATHAGYGAYGTNTTYTTYAARAAYATH MGNTAYMGNGCNCCNATHGTNACNGARAARATHGAYAARGARMGNTTYAAYYTNAARTGY TCNYTNTGYGGNCAYCCNGARCCN---------------MGNCCNTGYATHCARTGYTCN CAYGGNMGNTGYACNACNGCNTTYCAYGTNTCNTGYGCNTTYATGGCNGGNATHAARTTY GARMGNAGYGAYTGGCCNGTNCCNATHTAYATHTCNTGYMGNAARCAYGTNATGACNMGN MGNCAYGCNMGNGGNTCNACNGAYATGCCNGAYYTNGARATHYTNAGYMGNGCNYTNGCN AARCAYAARAAYAARMGNTAYTAYTGGGCNAARGTNGTNMGNGTNGARMGNAARAARYTN TAYGARGTNGAYTTYGAYGAYGGNTCNTTYAGYGARGAYYTNYTNCCNGARGAYATHGAR AGYCARGAYTGYYTNMGNGAYGGNCCNCCNATGAARGGNGAYCAYGTNYTNATHAARTGG GARGAYGGNAGYYTNTAYGGNGCNACNTTYMGNAARGTNAAYAAYCARGAYATGTAYATH GTNGARTTYGARGAYGGNTCNYTNTCNAAYGCNMGNMGNAAYGARYTNTGGGGNGARTAY GARGARATHCCNMGNCAYATHMGNAAYMGNATGTCNCARGCNACNGARCARMGNTTYGAY ATGTCNGAR---AARGARGCNCAYGAYGGNMGNMGNAAYAARAARAARGTNGAYTAYYTN AARATGYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGCNACNCCNGAYGTNCARMGNYTN YTNGAYATHCAYAARTCNYTNGTNTAYGAYGARGGNACNCARAARGTNAARTGYAGYYTN ACNAAYCAYCARATGCCNGCNAARGCNAGYGCNATHGARAGYTAYYTNAGYGGNAARAAR TAYAARMGNYTNGCNGAYYTNACNTAYTGYCCNTAYGARGARCAYAARGARCAYATHATH CARAAYAARAARAARGAR------AAYGARYTNTTYTGYACNYTNACNCARMGNCAYYTN GARAARACNGGNAARGCNATHCARMGNCAYATHAAYGGNMGNAARTAYAARAAYGCNYTN GCNMGNTGGAARGARTGYCARAARACNGGNACNAARTTYMGNCCNAGYAARGTNCCNCAR CARGCNGAYGAYGTNAGYAGYGAYAAYGAY---------GGNGAYGAYGAYGCNAARGAY GAYAARGCNGTNGAYGAYGAYGAYGARGAYGAYGTNGCNAGY------GAYGCNACNGTN GTNGARGAYGGNAGYGARAGYTCNGAYGARGARGAYGAYCARGTNGARGAYAAYATGAGY GAYYTNTAYCCNGCNGCNGAYGARYTNAAYGGNGARGAYGAYGAR--------------- ------------------------------------------------------------ ---------CCNYTNCCNCCNGGNGGNATGGGNNNNCCNNNNNNNGGNGARNNNNNNCAR TTYYTNATGAARGGNNNNGARTAYTAYNNNGARAARNNNNNNGARNNNGGNNNNATHTTY AARNNNAAYNNNYTNGGNAGYNNNNNNNNNMGNNNNNNNGGNGCNGANNNNNNNMGNNNN YTNNNNGANNNNGARCCNNNNCARYTNACNATGAARTGGCCNAARNNNGTNAAYNNNNNN NNNGGNNNNAARNNNNNNNNNACNNNNATHGGNCCNGARCAYACNNNNYTNAARNNNNNN YTNNNNAARGCNNNNNNNCCNNNNMGNYTNTCNGANNNNNNNNNNNNNNNNNNNNNNNNN YTNGANNNNNNNNNNNNNNNNTGGNNNGANAARNNN------------AARNNNYTNNNN TTYNNNNNNTGYGARNNNYTNNNNGCNGAYNNNATGYTNNNNNNNGTNNNNGGNTGYNNN NNNGARGANNNNNNNNNNNNNMGNYTNNNNCARGCNNNNAANGAYNNNNNNNNNAAYYTN NNNNNNGTNCCNATHNNNTTYCCNNNNNNNGGNTTYNNNAARGCNNNNNNNGCNMGNGAR ACNATHNNNAANTTYGTNGARNNNMGNATNNNNNNNNNNNNNMGNNNNNNNNNNNNNNNN NNNATGNNNNNNATNNNNYTNACNYTNCAYGGNGGNNNNNNNNNNNNNNNNGAYNNNGAR AARGTNAARGAYAAYNNNYTNGGNNNNATGNNNGCNGCNNNNGCNAGYYTNGCNGGNGGN YTNACNNNNNNNATNYTNYTNYTNGGNACNNNNCCNGAYGTNYTNGARAARGTNNNNGAR GARYTNAARGARTTYGGNYTNTTYGGNGARNNNGCNNNNGCNNNNNNNNNNTAYNNNYTN YTNGGNAARYTNGARTAYGTNNNNNNNGTNGTNAARGARTCNYTNMGNYTNNNNCCNCCN GTNGGNGGNTGYNNNMGNAARNNNGARAAYNNNNNNGANNNNGAYAARTAYNNNATNCCN AGYGAYTGGNNNGTNNNNTAYAGYATHMGNGAYACNCAYYTN---ACNGCNAARYTNYTN GARGANGGNGAYTCNTTYNNNCCNTCNMGNTGGATGAARNNNNNNNNNNNNNNNNNNNNN NNNGAYTCNNNNTCNTGYCAYTAYATNCCNTTYGGNNNNGGNCCNMGNATGTGYNNNGGN NNNCANYTNGCNAARATGNNNYTNNNNNNNYTNGTNGTNAARYTNNNNACNNNNNNNMGN TGGGARYTNAARAAYCCNAAYNNNCCNNNNNNNTAYYTNCCNNNNACNAARCCNNNNGAY GAYATGCCNNNNNNNTTY---GTNYTNGCNGCNTTYMGNACNYTNCAYMGNGCNMGNMGN GARGTNTTYGCNGGNGAYGARAGYGCNYTNTGYGARGTNMGNCARCARATHAAYACNCAR TTYMGNGARAARYTNCARGARACNGAYGARTCNAARATHGARGARAAYYTNGTNYTNGCN AAYGAYGTNGCNTAYYTNYTNMGNACNTCNGTNGTNCARYTNAARCARAARGARTCNGAR GAYGAYACNTAYGARYTNMGNATHACNAARAAYACNTAYYTNCCNGARAAYACNCCNTTY GAYCCNACNAARGARATGCCNYTNAARCARMGNAARAARAARAAYACNGAYTGYGTNGAY TCNAGYAAYTCNMGNTTYYTNGTNAARGCNAARGARATGAARGARTTYTTYMGNYTNACN GAYGARCCNGTNATHAAYGAYTTYYTNAARATGGAYAGYTGYAARMGNATHGCNGAYAAR TAYYTNATHGCNATGGTNTTYGCNTAYTTYAARMGNGCNGAYYTNGAYATHGARGARTAY AAYMGNACNAAYTTYTTYATHGCNYTNTAYYTNGCNCAYGAYGTNGARGARGAYGARGAR GARATHAARTAYGARATHTTYCCNTGGGCNYTNGGNGARCAYTGGMGNGARACNTAYGTN GAYTTYYTNMGNAARMGNGAYTGGYTNTTYMGNCARATHGAYTAYAARGCNATHATHAGY MGNAARTGYTGYGAYGARATHATGAAYATHGARCCNGARCAYTCNYTNTGGAARMGNGAR MGNGCNYTNCAYCAYGCNGGNGCNATHMGNAGYTAYATGAARGAYCCNMGNGAYAAYGGN ATHCCNMGNGGNCCNGAYGCNAGYCCNYTNYTNTGYCCNGARTGYGAYGCNTGYGAYAGY CARTAYGAYGARTCNAGYTCNAAYAGYYTNGGNTGGYTNATHTCNCCNGGNGTNTCNTCN ---------GTNTTYYTNCARTGYYTNGARTGGYTNAAYTCNGARCARGARACNYTNCAR ACNYTNGGNTGYYTNGCNATHGGNAAYTTYGCNMGNMGNGAYTCNTAYTGYGTNGARYTN GTNGAYAARGGNATHGTNGGNAARYTNGTNACNYTNYTNAARTCN---CCNGARAARTCN TTYTAYGTNCARCAYGCNGTNYTNAGYACNYTNMGNAAYYTNGCNATHCCNGTNCCNAAY AARCCNMGNYTNYTNGARGARGGNGTNATGGARGCNTGYYTNTGYYTNAARACNTCNGAR ATGYTNACNGTNATHTTYAARYTNYTNGGNYTNYTNMGNATGYTNATHGARGGNCARGAR TCNGCNGCNATHAARYTNGGNCARGAYMGNGGNTTYYTNGAYTGYYTNTGYGARTGGTGY TCNCARGAYGTNCAYGCNGGNGTNGARGGNGARGCNCCNMGNGTNGTNGCNTCNYTNATH AARAAYAGYAARTCNGTNATHGTNATHCARAAYYTNATHMGNGCNAGYTGYGTNGGNCAY YTNGTNTCNATGACNCARAGYGARCAYYTNGTNATGCARAAYGARGCNGTNATGGCNYTN ACNTTYGTNTGYAGYACNTCNYTNGGNGARGCNGCNGTNGCNYTNMGNGARGCNGAYYTN GCNGGNGTNGTNTCNAARYTNYTNAARGAYGARAARYTNCCNGCNGARATGACNGARGCN AAYAARATGTTYYTNCARAGYTTYATHTCNAARGGNATHATGAAYACNMGNGARGTNAAR GCNTGYTAYGCNYTNTGYAARAAYAARTCNTCNGARCCNGTNGAYGARGAR---TCNATG AAYGARATHYTNGAY---------------TTYGTNMGNAARATHAAYCAYGCNATHTCN TCNTTYAAYYTNGARATHAARAARGGNATHCARGARCAYGAYGGNTCNAGYGTNTAYTGY YTNGTNAAYACNGTNGARACNTCNATHACNMGNYTNTCNTCNACNTAYAGYCCNAAYGAR YTNGARYTNTTYAARAARYTNATHGARATHATHGTNGARTCNGARGAYGGNGTNATHGGN TCNMGNGTNGCNYTNAAYYTNACNGAYAARYTNGARAARMGNATGGGNAARGARGARGCN CARAGYGTNYTNAAYAARYTNGARAAYGARMGNTGGATHATHAARGAYGGNAAYGGNAAR ATHTCNYTNTCNGTNMGNACNYTNYTNGARYTNGAYCARTAYYTNCARGAYGTNTAYACN GAYYTNGTNAARATGTGYAAYYTNTGYAGYAARYTNTGYATHYTNGGNGAYTCNTGYATH AGYTGYGGNATHMGNATHCAYYTNAARTGYGCNAARACNYTNTTYTCNAARCARACN--- GAYAARAARTGYCCN------CAYTGYAARCARCCNTGG--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARYTNGAYAARYTNYTNTCNCAYCAY MGNGARGARGTNAARAARGAYGARATHCAYCARAARATHAARAGYGAYYTNYTNCAYTCN ATGGARGARGGNTCNCARACNYTNTCNYTNAAYGGNGARTTYGCNGARCAYATHGARCAR YTNGARGTNGCNGCNCCNGARYTNYTNACNGAYCAYCCNAGYATGACNGTNTTYAAYCCN GAYAARTTYTGYTGYYTNTTYAARGAYAAYATHAAYCCNTTYTCNTGYGGNTTYTCNMGN TCNCAYTTYTCNAARATHGAYAARGTNTTYGCNACNTTYMGNTCNGAYAAYYTNATHCCN YTNYTNATGTCNAAYACNYTNCCNTCNTGYTTYCAYCARGTNTCNAGYCCNCAYTGYATH ATGATGTGGYTNTTYAGYYTNYTNTCNATHCAYCCNTCNYTNACNGCNGTNMGNYTNATH AGYCAYACNATGAARACNATHATHCAYGAYATGTGGMGNCARCAYGARGAYGAYAARGGN TCNTCNATHCARACNTGGTCNCCNAARCCNATHGARATHACNMGNATHYTNGTNAAYATG GGNGCNAAYCCNTCNTAYYTNYTNGGNGAYCARGCNYTNTAYTCNTCNGAYGARATHAAR GARCAYYTNTCNGTNGARAAYGAYGARAAYGAYTCNATGCCNGCNMGNTCNCCNGGNMGN YTNAARATHGARAAYTTYMGNAGYGTNYTNGARGTNYTNACNAARTGYTTYMGNACNAAR CCNGAYTAYACNMGNGARGARATHCAYYTNATGGTNTGYYTNGTNATHMGNYTNTCNGTN GAYGCNTCNTTYCARAAYYTNGARYTNCAYCAYGTNTTYCARGARYTNYTNTCNTCNYTN YTNGARTGYAGYAARGAYTCNGAYTGGATGTCNGGNGTNCCNTCNYTNTGYCAYGARYTN GCNACNGTNCCNCARCAYCAYACNTGYTGYACNTAYGTNGTNGAYYTNATGCCNYTNAGY MGNMGNGGNAAYTAYGTNMGNACNMGNYTNAGYTAYYTNTTYYTNTGYTCNATGATG--- ---------GAYGAYCARCCNAAYAAYGARYTNGAYCAYGTNTCNCCNTCNMGNATHTGY CARYTNGGNTCNTAYCCNACNACNGCNCARCCN---TCNMGNYTNTAYYTNTGYYTNCAY MGNYTNACNAARGARGAYATHAGYAARATGAAYTCNGCNGTNACNYTNYTNGAYMGNGCN GTNGGNGAYGARATHAAYMGNAAYGCNCAYCCNAARGCNGARYTNGARTTYYTNACNAAY CARGTNAARATGGTNATHMGNGAYATHMGNGAYAGYATHAARACNYTNGAYYTNTCNAAR GTNAARGAYMGNATGACNATHATGACNAARAARTGG---ATGYTNTCNAGYCARAAYACN AARAGYGTNCARMGNAGYATHTTYTCNTGGGTNACNTCNMGNGCNAAYGTNCCN------ GARGARAARYTNAARGAYAAYGTNCCNACNACNGCNGAYGARGGNATGGAYATGAGYGGN MGNAAYMGNAARGTNMGNGTNTGGGGNMGNYTNMGNCCNACNGCNAAYTTYGCNTAYGAR AAYGTNGARGTNYTNCCNGAYAAYAARGGNATHAAYATHCAYATGMGNMGNGAYCCNAAR AARGGNGTNGTNAAYAAYCARATHYTNGAYTGGTCNTTYAARYTNGAYGGNATHTTYAAY AAYGCNGAYCARGARGTNGTNTAYAAYACNGTNACNTCNGAYGTNGTNTCNAGYTCNYTN GAYGGNTAYAAYGGNACNYTNATGTGYTAYGGNCARACNGGNTCNGGNAARACNTTYACN ATGACNGGNGCNACNGARAGYTAYMGNCAYMGNGGNYTNATHCCNMGNGCNATHTCNCAR YTNTTYMGNCARATHGARGAYMGNYTNGARTAYAGYATHACNGTNMGNGTNTCNTAYATG GARATHTAYAAYGARCARATGTTYGAYYTNYTNGGNACNTTYCCNGARAAYGGNTGGAAY AAY------AARGARYTNAAYAGYAGYCCNGAYCCNATGGTNATHTCNGARAAYCARGGN GGNGTNTTYGTNAARGGNYTNTCNTGYCAYYTNGCNCARAAYGARGARGARGCNYTNAAY YTNYTNTTYGARGGNGARACNAAYMGNTCNATHGCNGCNCAYTCNYTNAAYAARGTNTCN TCNMGNTCNCAYTGYATHTTYACNGTNTAYATHGARTCNMGNTCNMGNGTNCARTCNAAY GCNAARTAYACNGTNTCNAARYTNAAYTTYGTNGAYYTNGCNGGNTCNGARMGNYTNAGY AARACNAARTCNGARGGNAARACNAARGARGARGCNATGTAYATHAAYAARTCNYTNTCN TTYYTNGARCARGTNGTNATHGCNYTNGCNTCNAARACNMGNGAYCAYGTNCCNTTYMGN CARTCNAARYTNACNCAYTTYYTNAARGAYTCNATHGGNGGNAAYTGYAAYACNGTNYTN ATHGCNAAYATGTGGGGNGARAARCCNCARYTNGARGARACNGTNTCNACNYTNMGNTTY GCNACNMGNATGATGTGYGTNGCNAGYGARCCNGCNGTNAAYGARATHTAYGAYCCNGCN YTNYTNGTNAARAARYTNCARAARGARATHTCNCAYYTNAARTCNGARYTNGCNATGCAY GAYACNYTNACNAAYMGNAGYATGATHTCNTAYGAYCCNYTNTCNGARCARCARAARTAY GARATHMGNTGYCARATHMGNMGNTTYYTNGARGGNAGYYTNGAYGARATHGAYATHGTN AAYYTNMGNCARATHGTNGGNTGYTTYGAYACNTTYAARGARYTNTAYAAYGAYATGGAR AARGARATGGARGCNAARYTNMGNGARAARTTYATGYTNATHGAYAARACNGAYCCNAGY TCNATHGCNGCNGCNCARCARAARYTNCARGTNYTNAARGARGCNTTYGTNGARAARGCN AARGTNGCNGGNATHCCNATHGCNGAYGAYGGNTCNTAYGTNGGNGAYYTNGARGGNGGN GGNTTYGGNGTNGGNACNGCNCCNMGNAGYGCNAARGGNGAYACNTCNGCNGTNGTNCAR YTNAARMGNAARGARMGNGARMGNGARMGNAARMGNGGNTCNMGNGGNGCNAAYAGYCCN ATHGGNGTNAARCCNGCNTCNAGYCCNTCNCARAGYGTNMGNGGNGARGGNAARGCNGAR TCNCCNCCNACNCCNGTNGGNGARMGNGTNGAYAARGARCARCAR------GARGGNTCN GCNTCNCCNGTNTCNTCNACNGGNAAYYTNTCNMGNNNNNNNNNNMGNNNNMGNNNNNNN NNNGTNCCNGARGANNNNNNNNNNGCNCCNAARCCNGARACNMGNCARCAYACNCCNCCN ACNMGNAGYGCNGCNTTYGARGARTTYAARACNGAYMGNGGNAGYGARATHAAYMGNATH YTNGTNGARAAYAARGARTTYYTNTCNAAYTCNAARAARACNTAYTCNGAYYTNGCNAAR CARATGAAYAGYYTNAARAGYAAYATHGAYMGNTCNMGNCARMGNYTNGAYGAYYTNAAR GARGTNMGNGARTCNGARGGNCCNATHYTNAAYGARGAYGGNGAYATHGTNATHAGYGAR GAYGARTTYAARGARATHACNAARYTNMGNGARYTNAARACNTCNTAYMGNAGYAARMGN GAYGARYTNGCNAARACNGARTCNGARGTNAARTAYTGYCARAARYTNGTNGAYCARTGY MGNYTNMGNYTNATHCARGARTTYGAYAAYTGGTAYAGYGARAGYTTYYTNAGYGCNGCN GAYGARAAYCARACNAGYYTNGGNGTNGGNAGYGGNGTNMGNCCNGGNGTNATGYTNCCN ATHACNAGYYTNGCNAAYGARGAYGARCARGARAARTTYGARMGNYTNCARYTNGARYTN ATGATGAAYAAYCCNGARTCNGCNGCNTTYTAYAAYGCNCARATGMGNACNTCNMGNMGN AARATHTAYGGNGCNGCNYTNAAYCARCCNCARCCNGCNTTYMGNMGNCARGCNGGNACN CCNACNATGAGYTTYMGNAAYCARCCNCCNGGNGTNATGCARGTNCARTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNTCNGCNATHTTYGARTGGAAYATHGCNAAY TAYTGYGARAARYTNGARATGGARAARMGNGGNACNATHCAYTTYACNGCNTCNGARCCN TTYTAYATHGGNCAYTGYGGNCAYYTNGCNMGNYTNGARGTNTAYYTNAAYGGNAGYGGN TGYGCNAARAAYAAYTTYATGTCNGTNTAYYTNMGNGTNYTNCARGGNGCNTAYGAYGAY TTYYTNCARTGGCCNGCNGTNTTYTCNYTNACNTTYATHYTNATHAAYCARGARGAYAAY ATGCAYGGNTCNYTNYTNTTYMGNAAY---GAYMGNACNGTNTTYGARTAYCAYAARCCN TCNTCNTAYAARGARTAYTCNGARGAYATHTGGGGNYTNGTNGARTTYGTNTCNCAYTGY GCNATHCARAAYAARAARTAYATHAARGAYGAYATGATHAARYTNMGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MGNAAR------TTYCCNATGTAYATHGTNGAY GCNTTYACNAARAARGCNYTNAGYGGNAAYCARGCNGCNGTNTGYYTNATHCCNTCNGAY ACNACNYTNTCNGAYGAYGARATGCARAARATHGGNGCNGARATGAAYYTNTCNGARACN GCNTAY------ATHYTNGARAARGAYACNGAYTTYATHACNGGNAAYAARTTYTCNYTN MGNTGGTTYACNCCNACNACNGARGTNAAYYTNTGYGGNCAYGCNACNYTNGCNTCNGCN GCNGTNYTNATHGAYGGNGTNGGNAAYACNAAYAAYGTNATHGARTTYTCNACNAARAGY GGNACNYTNTCNGTNAGYMGNCAYCCNGAYAARACNGGNTTYYTNACNATGGAYTTYCCN AAYAAYAARCCNGCNCCNCARGAYACNGARAARYTNGARAARYTNYTNYTNAGYGTNGTN GGNGAYGCNGAYATGATHCARGARGTNCARTAYTCN---TCNACNACN---AARAARYTN GTNMGNYTNAARGAYCAYATHCAYMGNAARGARYTNGARMGNYTNAAYCCNCARGCNGGN ACNYTNATGGARGCNGARCARCCNGGNTTYGTNAARGGNGTNGGNGTNACNYTNAARGGN TGYCARGCNAAYGGNTGYGTNGAYGARGAYGGNAARYTNTAYGAYTTYGTNTCNMGNTAY TGGGCNCCNTGGATGGGNATHCCNGARGAYCCNGTNACNGGNTCNTGGCAYACNGTNATH GGNCCNTAYTGGGCNGARGARYTNGGNAARACNACNYTNTAYGCNMGNCARTGYTCNTCN MGNGGNGGNGAYYTNYTNGTNGARGTNAARGAYACNMGNGTNACNYTNATGGGNCARTCN GTNATHAAYYTNACNGGNACNTTYCARYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TAYYTNTCNMGNYTNCAR CCNCCNYTNGCNTCNTAYAARAAYTAYCAYAARATGGAYGARGAYGTNGARCARATHTCN GAYGAYGGNATGATHGCNGTNGARAARTGYYTNGGNAARGGNGGNTAYGCNACNGTNTAY AARATGTAYAARGTNTTYGARGCNATGAARGTNCARAAYCCNCCNTGYCAYTGGGARTTY TAYATHTCNTGYGARATHCARAARMGNYTNTCNGCNYTNMGNGCNGCNATHGAYGTNMGN CCNTCNGTNATGAAYGTNAAYTGYGGNTAYTTYAAYTCNTCNYTNAGYATHYTNATHATG AARYTNCAYGARCAYGGNTCNYTNYTNGAYYTNGTNAAYYTNTAYAARTCNGAYCCNAAR YTNYTNGGNCARGTNGARCCNTTYGTNTGYYTNGCNACNGTNGARYTNYTNCAYYTNTTY GAYCARYTNCAYAARTGYGAYATHATHCAYGGNGAYGTNAARCCNGAYAAYTTYYTNYTN ATGGAYYTNCCNTCNGTNTGYGARAGYMGNAAYCCNCARGAYGTNTTYGGNTCNCARYTN MGNGTNTTYTGYYTNACNGAYTTYGGNCARACNATHGAYATGCAYATGTTYCCNGCNGGN ACNTCNTTYAARACNAARACNAAYACNGAYGGNTTYGARTGYATHGARATGMGNACNGAY MGNCCNTGGACNTAYCARACNGAYYTNTTYGGNYTNGCNGGNACNATHCAYGTNYTNYTN TTYGGNTCNTAYATGAARGTNTTYGTNGARAARGGNGTNTGGAARATHACNGGNAAYTTY GTNMGNAARTGGAAYGTNCCNYTNTGGAARAARYTNTTYCAYCARYTNYTNAAYATHCAR TCNTGYGAYAGYYTNCCNGAYYTNACNTCNYTNMGNGCNGARTTYGARGARTAYTTYTGY TCNAGYYTNATHTCNTCNTAYAAYGARTGGGCNMGNAARYTNMGN--------------- ------------------------------------------------------------ ---------------------CAYATHYTNTCNATHCAYGAYAAYGCNAARAARATHYTN AARGAYAARGARTAYYTNTGYATHGARGCNTCNGAYCAYCCNGAYCARGARYTNACNAAR TTYTTYCCNCARTGYATHAARTTYATHCAYAARGCNMGNYTNGAYGGNGGNGCNGTNYTN GTNCAYTGYYTNGCNGGNGTNTCNMGNAGYGTNACNGTNACNGCNGCNTAYATHATGACN TCNACNGARYTNGGNTGGMGNGARGCNYTNAAYTCNATHMGNGGNGCNMGNAGYGTNGCN AAYCCNAAYTTYGGNTTYCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARAARYTNAAYATGGAYTCNTTYAGYAARYTNTAY GARTAYTAYTCNCARTAYAGYTCNCAYTTYGAYGAYCCNYTNGAYAAYAAYYTNGGNGTN MGNTCNYTNAGYCAYATGATHAARATGYTNCARAAYAAYGTNATGACNAARAARNNNAAR AAYGTNGARYTNYTNCAYGGNGCNGCNGARGTNACNMGNACNYTNMGNGGNYTNMGNGTN ACNTTYTGYAARAGYGGNAARGAYMGNACN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNMGNGCNGCNCAYTGYMGNGTNGARGAR ATHGCNMGNGCNAARTGGATHTGYYTNAAYAARATHACNTAYAARGAYCCNAAYGGNACN GARMGNGTNTGGGARGGNGTNTCNMGNACNACNAARAAYACNGGNGARGCNGAYGCNGTN GGNATGGTNGGNGTNTTYMGNGAYCCNATGACNGAYYTNCCNAGYATHATHYTNATHMGN CARTAYMGNCCNCCNATGGARACNTAYACNATHGARTTYCCNGCNGGNYTNATHGAYAAR GGNGARACNGCNGAYGTNGCNGCNGTNMGNGARATGAARGARGARACNGGNTAYGAYGTN ACNGTNGTNGAYGTNTCNCCNGCNACNTCNYTNGAYCCNGGNGTNGGNAGYACNACNYTN AARATHGTNACNGTNAARGTNGAYACNAGYAARYTNAGYAARGAYGARMGNCCNAARCCN ACNGGNGGNGAYGCNGAYGARTTYGTNCARGTNATHGTNCARCCNATHGCNGGNYTNATG GAYAARYTNAARGARTTYTCNGAYCARGGNGAYTGYGTNGAYTCNMGNGTNTAYTCNATH GCNATHTCNGTNGGNMGNAARCCNGGNTGYAARGAYGGNCCNGTNTTYYTNATGYTNTGY ACNGCNCARAAYMGNAAYGGNGAYAARTAYAARATHCAYMGNAAYATHGARGGNATHTTY TCNAARTTYATGAARGARGGNAARGCNACNATHMGNATHGTNGAYCCNCCNMGNGAYATH GCNYTNAGYAARGCNGAYCCNACNCARYTNTGYACNTTYYTNAARATHGTNMGNYTNTCN CAYGARAARAARGAYGTNCCNGAYAARGCNYTNAGYATHYTNGCNCCNGCNTCNGCNAAR CARGTNGARAARCCNGTNACNAARYTNYTNGTNACNAARCCNTCNGARTAYCCNATGTCN TTYCCNAARACNYTNGARATHYTNATHGTNAAYGARTGYYTNYTNMGNMGNGTNAGYCCN CARATHGTNGCNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARGARAARGGN GTNAARCARGARGCNGARGARGARGARAARMGNGARGCNGAYGGNGAYGAYTCNGARGAR GAYYTNGAYYTNGAYGAYYTNGAYAAYATHGAYMGNGTNYTNGARAARGCNYTNGARAAR AARMGNGARAAYAARGARACNGAYGAYAARACNACNGAYGARGCNCCNCCNGARTCNTCN CAYAARACNTCNTCNTCNYTNACNGTNGARACNAARCARACNGARGARAARGAYMGNGGN GARAAYGTNGARGAYTCNACNATGAGYGAYACNGAYATGAARMGNYTNAARTAYTCNGTN AARGAYTCNGCNGARYTNGCNYTNAAYAARYTNCARTTYYTNGAYATHTCNACNAARAAY ATGTCNAARYTNCARATHYTNYTNGTNGARYTNCARACNMGNTAYAAYGAYTGGCARTCN GGNGGNYTNTCNACNYTNTAYTTYCAYAARCARYTNAARTCNTCNGARGCNYTNYTNTCN CARTAYGARGARAGYGCNGTNCCNTCNGGNTGGTCNTGYCARTGGGAYMGNGCNAGYTGY MGNTAYTTYTAYMGNAAYGARAAYAAYGGNCAYACNCARTGGGARTAYCCNCARGTNACN TCNTCNTCNTCNGARCARCCNTCNTCNTCNTCNACNACNACNACNGCNACNACNACNACN ACNTCNTCNMGNAGYGGNGAYCCNAARGARTCNTCNACNACNACNAGYAGYAGYAGYAAY MGNGGNMGNAGYAAYAARAARMGNMGNAARAARGAY---MGNGGNAARMGNGAYMGNMGN AGYGGNAGYTCNCAYCAYCAYMGNAARAARAARMGNMGNMGNMGNGAYCAYAGYAGYAGY AGYAGYAGYTCNGARGARGARAAYACNACNTCNCAYCAYMGNCAYAGYMGNAGYAARMGN AARAARMGNGGNMGNTCNGAYAARTCNCCNAGYYTNGARGTNATHGAYGAYCCNGGNGTN AAYATHGTNCARGTNATHGARGAYAGYCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GTNATHTTYMGNATHAAYGAYAAYGGNTCNGGNCCNGARYTN YTNCARCARGTNYTNYTNGARMGNGGNTGGATHGARTAYGAYGARGARGTNCAYGGNCCN GAYGARTGGCAYYTNTGGTGGMGNACNACNMGNTTYMGNACNGGNGARTAYAAYAAYYTN YTNCCNTGGCARTAYATHAAYCAYTTYCCNAGYTGYACNYTNATHACNAARAARGAYGCN YTNTGYMGNAAYYTNMGNAARATGMGNATHATHCAYGGNYTNAAYGTNTAYAAYTTYAGY CCNAARGCNTTYAAYYTNCCNAAYGAYTAYACNAARTTYGTNTCNGARTAYGCNGCNCAR MGNCARAARACNAARGCNGAYGGNAAYCCNTCNATGTGGATHTGYAARCCNGCNGARTCN TCNMGNGGNMGNGGNATHTTYATHTTYCAYGARYTNTCNGARYTNCARTAYGAYTGYAAY GCNGTNGTNCARCAYTAYATHGAYGAYCCNYTNYTNATHGGNGGNTAYAARTTYGAYATH MGNATHTAYGTNGTNATHCCNAGYTTYCAYCCNYTNCARATHTAYATHCAYGARGARGGN YTNGTNMGNTTYAGYACNGARAARTAYGAYYTNGCNMGNYTNGAYAAYGTNTTYGCNCAY YTNACNAAYACNAGYATHAAYAARTTYAGYCCNGGNTAYACNACNGAYAARGARGARGTN GGNCAYGGNTGYAARTGGACNATHTCNCARYTNMGNMGNTAYTTYYTNCARAAYAAYATH GAYGAYACNMGNATHTGGCARCARATHATHAAYATHGTNATHYTNACNGTNYTNATGCAR GCNCCNTCNGCNCCNAARATGATGAAYTGYTTYGARYTNTAYGGNTTYGAYATHYTNATH GAYAGYGCNYTNAARGCNTGGYTNYTNGARGTNAAYTTYAGYCCNGCNYTNAGYTCNGAY TGYCARGCNGAYATHNNNGCNAARAARGCNATGYTNCAYGAYYTNATGAGYYTNATHTAY AAYMGNGGNGARATHMGNAGYGTNYTNTCNATGATHGAYGGNGGNAAYAARAGYAARAAR CARGGNAAYAAYATHACNGGNYTNTCNAARAAYATHTCNGCNTTYGGNATHGCNGGNTTY GTNMGNTTYYTNGARGGNTAYTAYATGATHYTNATHACNAARMGNAARAARGCNGCNATG ATHGGNCAYCAYACNGTNTAYAARATHGARGAYACNTCNATGYTNTAYATHCCNAAYGAY GTNGTNMGNCARACNCAYCCNGAYGARAGYMGNTAYGTNAARATGTTYCARAAYGTNGAY YTNTCNAGYAAYTTYTAYTTYAGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TGGTCNCARCCNTCNCCNATGTGGAAY ATGGAYAAYGTNAAYGAR---AARTCNCARGCNTAYAARATGCAYYTNGARAAYATGAAR MGNGARMGNGARGARGARAARYTNAARGARGARGARMGNYTNAARCARGARYTNATHGAR AGYAARCARGARGARYTNMGNAARCARCARCAYGARYTNCARMGNCARMGNGARCARATG MGNMGNGARAARGARGARATGGARAARGARMGNYTNAARAARYTNGARGARGTNMGNMGN GARGARGARMGNATHGCNCARYTNGARATGGARMGNCARAARAARGARCARATGGARCAY CAYATGMGNATGCARGARGARAARAARMGNCARGAYGAYCARGARATGAARAARCARGAR GAYAARMGNMGNAARGARGARGARAARMGNAARGARGARGARAARYTNMGNAARGARGAR GARAARATHAARGARCARAARMGNAARGARGARCARAARMGN------------GCNAAR GARGCNGARGARYTNMGNMGNCARCARGARAARCARGARMGNGARGCNGCNGARGCNMGN CARMGNGARGARATGCARMGNCARYTNGARYTNCARCAR------ATHCARGARGARGAR GARMGNATGMGN---MGNGARAAYGCNGARGCNGARMGNCARCARCARGCNYTNAARAAR CARYTNGARTCNCARAARCAYCARGARTCNYTNMGNAARYTNCARCARGCNCARAARGAR CARYTNGCNAAYATGCARYTNCCNGCNTCNAGYAAYTGGGCNAARCAY---GCNGCNCAY GGNAGYGTNGGNCAYTCNAARTCNYTNACNGARATHCARGARGARGARGCNMGNMGNGAR AARGARMGNCARAARGARCARCARGCNYTNAARCARMGNATGCARGARCARGCNGCNGTN ATGCARCARCARCARCARCCNAARTCNTGGGCNTCNCARGTNTCNAARGGNACNCARMGN GGNCCNTCNYTNYTNGAYATHCARCAYCARGARAARGARAAYGCNAARAARGCNGARAAR GARMGNGGNAARGCNAGYCAYCARTCNAARTAYAAYYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNCCNATHGAYACNGAY GCNGGNAARYTNAAYTAYCARGARCARAARAARCAYYTNGCNGARGARMGNMGNMGNGAR TAYAAYCARYTNYTNCARCARAARTCNCARCCNMGNTCNMGNCARCCNGARCARGARATH GAYAAYCCNTCNATHATHCCNTTYAAYMGNGTNGARCARGARMGNYTNAARGCNMGNATH YTNGARGARGARMGNCARMGNGARTAYAAYCARACNYTNGCNAARATGCARGARMGNCCN MGNAARMGNGARGTNACNCCNGTNCCNAAYTTYGAYYTNCARGGNCARGARCARGARAAR MGNYTNCARAARGARMGNGARCARMGNGARTAYAARGCNATGYTNGAYAARCARCARGAY CARCARAARCARATGATGYTNYTNCARCARGGNGTNCCNTAYGARAARGTN--------- ------------------------------------------------------------ ------------------------------YTNCARGCNTAYACNCCNCCNYTNTCNYTN TGGAGYYTNGTNGARCARCAYGTNCCNGCNTTYGARYTNGARGARGTNAARGGNATHYTN GGNTCNAAYYTNGTNGAYCARAGYYTNGARYTNCAYAGYGARATHGARATGYTNYTNGAY ATHTGGMGNGAYATGMGNGAYGARGTNCARGARAAYAARYTNATHAAYTCNMGNYTNCCN GARCCNCCNAAYCARMGNGARMGNYTNATHCARGARATHAAYTTYTTYGCNGARAAYATH AARGARAARGCNMGNACNAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GCNACNGARATHTGY AAYAARGCNAAYGARGARTAYGTNGARGARAAYTAYCARAARGCNATHGAYYTNTAYACN GARGCNYTNGCNYTNGARGGNACNMGNGAYGAYATHTAYTGYTTYMGNGGNCARGCNAAR YTNTCNYTNGGNAAYACNTCNGAYGCNATHAARGAYTAYGAYGARGCNATHMGNYTNAAY CCNATHAAYCARAARGCNTAYATHAARAARGGNTCNATHYTNYTNAARATHGGNGARGTN TTYCARGCNCARAGYGTNTTYAARGARGGNCARAARCAYTGY---GGNGAYAARGAYTTY GARGAYTGGYTNAGYAARGTNGARAGYMGNATGCARTCNGTNAARGCNTCNACNGARTCN GTNCARGTNCCN------------------------------------TCNATHAARTAY AAYTGGTAYCARACNCAYACNCAYGTNATHGTNACNGTNYTNGTNAARAAYGTNCARAAR GARGARYTNAGYGTNGAYACNGARGGNMGNYTNYTNMGNGTNGGNATHAAYMGNGGNGAY CARTCNAGY---GAYYTNAGYATHMGNYTNGCNCAYCARGTNGTNCCNGAYCARACNCAR TCNAARYTNTTYGCNACNAARGTNGARATHAARYTNAARAARTCNGARGGNATHCARTGG GTNAARYTNGARGGNTCNCCNGAYGAYGTNGAY---AAYGTNYTNCCNGCNTGYGCNGCN CCNGTN---GCNGCNGARGCNCCNMGNTAYCCNAGYTCNTCNCAYTTYTCNMGNGAYTGG GAYAARYTNGCNGCNGARGTNACNGARGARGARAARAAYGARAARYTNGARGGNGAYGCN GCNYTNAAYCARTTYTTYCARAARATHTAYGCNGAYGCNTCNGAYGAYACNAARAARNNN ATGATGAARTCNTTYTCNGARTCNGGNGGNACNGTNYTNAGYACNAAYTGGGAYGARGTN GGNAGYAARAARGTNGARGTNAARCCNCCNGAYGGNATGGARTAYAARAARTGGGAR--- ---AARATGCCNAARMGNAARGCNGCNGARGCN--------------------------- ---------ACNGCNGARTCNCCNAARAARGCN---AARATHGARGARAARCCNGCNAGY GCNAGYGGNMGNGGNMGNGGNMGNCCNCCNYTNTCNGCNGARGARAARGCNAARMGNGCN GCNAAYAARAARCCNTCN---GGNMGNGGNMGNGGNMGNCCNAARGGNTCNACNAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNGGNTCNCCNGCNMGNCCNGAYCARCAYATHAGYGGNTCNCCNAGYYTNYTNMGNGAY CCNGTNATHYTNGARATHTCNGCNMGNTGYAARMGNACNGCNGCNCARGTNATGYTNAAY TAYYTNGTNCARTGYGGNATHGTNGTNYTNCCNAARAGYAAYATHAARGARMGNATHCAR GARAAYYTNGGNTGYYTNGAYTGGTCNYTNAGYGAYAAYGAYTTYAARGCNATHCARGGN YTNGAYMGNGGNATHAARYTNTTYGARTTYYTNTAYATGMGNGGNCAYCCNGAYTTYTTY GARGGNGARGARTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MGNACNYTNGCNTGY AARGCNYTNNNNGGNATGTCNMGNTCNGAYACNATHMGNCARATHATHGGNAARMGNCCN CCNYTNAAYAAYGGNCARYTNCARTCNYTNGTNAARGARCCNGTNYTNGCNGAYAARMGN ACNGTNCAYYTNYTNTTYTGYGARTAYGCNTCNACNYTNYTNGARAARATHGCNGGNAAR GAYACNTCNGTNTTYGGNGCNACNACNYTNGARGARATHMGNMGNGCNGGNGTNGTNGCN CARACNAARATHGTNTAYCAYGAYMGNGARYTNYTNCARYTNATHCAYGARCAYYTNACN TCNAARGGNYTNCARGTNGCNGCNAAYGCNYTNCARAARGARGCNAGYYTNCCNAARTGY CCNACNCCNCCNCCNCAYCCN------TGYACNCCNAARGCNMGNMGNCARYTNAGYCAR CCNAAYGGNCCNAGYGCNTCNTCNGCNTTYTCNCARAGYCCNTCNTCNTCNAAYGGNGTN CCNGTNTCNGGNCCNATHAARTTYAGYYTNAAYMGNACNCCNGGNCCNAGYAAYACNCCN CARTCNAAYYTNCARAARTCNAGYAARMGNMGNTTYGARGGNATGTTYCCNTCNGGNCCN TCNGCNAARGGNAGYAGYAGYGAYTAYGARGTNTCNYTNGAYAARATHGTNACNGARTAY YTNMGNAARCARCAYGCNYTNTGYCCNCARCCNATHTCNACNTGYCCNACNATGTCNYTN TTYYTNCCNCAYCARTGYCCNCARCCNYTNGGNAARGAYAGYGCNTCNGTNTCNATHGCN AGYMGNYTNTAYGARMGNCARATGMGNGCNCCNTAYGGNGGNCCNAAYGGNCARMGNYTN GAYMGNMGNTAYYTNTAYTCNMGNATGGCNYTNYTNACNACNTAYMGNGAYACNGCNAGY GAYGGNYTNGCNTGYTGYGGNTTYGAYTGYGGNGGNGAYACNYTNTTYGTNGGNTCNTTY GCNGGNGARYTNMGNGCNATGCCNATHAAYTCNGAYAAYGAYGAYTAYGTNAGYACNATH TGYCAYTCNTCNGCNGTNATHAAYATHAAYACNTCNATGGTNGAYCCNGAYYTNATHATH ACNAGYACNTGGGGNGCNTCNCARAAYTGYGCNYTNTGGGGNTTYAARMGNGAYACNGAY ACNTGYGTNYTNAARTAYMGNTTYGAYGARCAYCAYGCNTCNYTNGCNAAYYTNAGYCAY GAYMGNTTYATHGGNACNAARGAYTTYGTNGCNACNATHTAYGAYACNGGNGCNGGNACN AARGTNCARACNYTNTTYGAYGARAGYAARGCNAAYAAYTAYAARTTYAAYGTNGCNTCN TTYAAYCCNACNGAYGAYYTNGTNYTNAAYGAYGGNAAYYTNTGGGAYGTNMGNTCNAAY AARYTNATHTAYAARTTYGAYAARTTYAAYCARTAYACNAGYGGNTGYTTYCAYCCNMGN GGNYTNGARGTNGTNATHAAYTCNGARATHTGGGAYATHMGNACNTTYMGNYTNYTNCAY ACNGTNCCNGCNYTNGAYCARTGYCARATHYTNTTYAAYCAYGGNGGNGAYGTNATHTAY GCNATHAARGTNGAYGAYGARYTNTCNGGNGAYATHTTYTCNMGNMGNGAYTAYGCNTCN ACNYTNACNACNTTYGAYGCNYTNAAYTAYTCNAGYATHGGNACNTTYGAYYTNAARACN CAYAGYATHYTNGAYYTNGCNGTNGAYMGNAAYGAYCARTTYATHAGYGTNATHGARAAY ATGGCNCARCAYGAYAGYGAYCCNGARGARTCNATHTGYMGNGTNTAYGARATGGGNAAR ATGMGNATHCCNGARGAYCARGCNGARGARGAYGAYGAYAAYGGNCARAAYAAYGAYGAY GAYTAYGAYGAYGAYGAYGAYGAYGAYGGNGARAAYGAYTTYGTNAAYGTNGTNGARTTY TCNGARACNGCNAARTTYGTNAGYAARTGYTTYAAYCAYACNGCNTTYGTNCARGCNAAY TTYMGNAAYAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CARTAYTTYAAYCARGTNAARAARACNYTNTCNYTNGAYCCNGAYMGNTTYTAYACNTTY YTNTCNYTNYTNAARGAYYTNAAYAARGAYCAYACNAGYCCNGTNGARYTNTAYYTNGAY ATGGTNTCNYTNYTNTCNGAYCAYCCNCARYTNGTNCARGAYTTYGCNGGNTTYYTNYTN TCNTTYCARGCNGTNGARTGYCAYTGYTTYGCNTCNCAYTTYCARTAYGCNCARATHMGN CARTTYYTNMGNCARGTNGARATHCAYTGYGGNTCNTCNAGYAGY---ACNTAYAAYAAR GCNYTNAARGCNYTNTCNACNTGGAGYACNATGTGYCARGARGGNACNYTNGARGGNGGN YTNMGNGAYAARATGGTNGCNATHYTNMGNACNGTNCCNGGNGTNYTNGAYAAYYTNATH AGYTAYTTYYTNGAYGGNGTNGTNTCNGAYTGYCAYGCNATGGAYTTYGARGAYGTNAAY YTNGARGARAARATGGARGARGGN---AGYGAYGAYCARTTYGARACNATHGTNYTNCCN GAYGARCCNGARGAYTAYAAYACNGARACNTGYACNTGYTCNTGYCAYAGYGARAAYCCN YTNGAYGAYMGNTTYCARCARMGNATHAARCAYTGYGTNTCNTGYAGYYTNCARATHTAY AARGGNMGNCCNGTNYTNAARAGYACNMGNAGYATGACNMGNCCNYTNTCNGTNGTNTAY CCN---------YTNGARGAYAARGARAARTGYTCNCARGCNAARATHGAYGCNGCNCAR ATHGTNYTNGCNAARGCNAARGTNCARCARCARCARAARGGNMGNAARMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AGYATGACNTCNTCNATHYTN ACN---CCNYTNCCNCCNAARAARYTNTTYCAYYTNGAYGAYACNAARGAYTCNGTNGAY TCNGARACNAARATGTCNGCNAAYACNGAYACNGARGAYATHMGNYTNMGNAAYACNATH AGYGTNGAYCAYGARAAYACNAARGAYTCNGTNGCNTCNGAYTCNGTNGCNGARGGNCCN ACNCCNTCNAARMGNAGY---MGNGGNTAYMGNGARGGNYTNGGNGTNATHGCNYTNGGN GARACNAARCAYTTYACNGCNGARACNYTNTTYGARTAYCARTGGCCNCARGAYGGNGGN GARTGGCAYATGYTNCARGARCARATHAGYGARTTYYTNAARGTNAARTCNTTYAARMGN AARTAYCCNGAYYTNTAYMGNMGNGTNTGYGAYAARGARGARAARGAYTTYYTNMGNGAR AARGGNGTNGTNACNGARACNCARTCNGAYYTNGGNYTNACNGCNYTNMGNAGYGARGAR GTNTAYGAYYTNATGATGAARGAYTAYAAYGAYMGNTAYCARGARTAYYTNACNGTNYTN CARGARAARCARAARMGNGTNATGMGNGARAARCAYMGNGARTAYGGNGTNGCNAARYTN GAYAARTCNAARATGGARGCNTAYAGYAARAARGCNGCNMGNTGGGCNGCNGARTTYAAY GCNAGYYTNATGMGNGARAARMGNGARGARMGNCARGCNTAYTTYGAYYTNCARACNTAY ACNATHCAYCAYACNAARAAYMGNTTYMGNTCNYTNCCNCCNGCNAARACNAARATHGGN TCNTAYCCNGTNGCNYTNATHACNGGNCARTAYCARGAYAARTTYMGNCARTAYCARCCN GARGARYTNTGYAAYTTYCCNYTNAARACNGCNYTNGTNGAYCCNCCNCCNMGNGTNAAR TAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNCCNGARTGYYTNATHATHTCNMGNGTNYTNGTN GGNYTNCAYTCNGGNTGGAAYATHGCNGTNTGYCCNATGTAYYTNGCNGARATHTCNCCN AARAARATHMGNGGNGCNATHGGNACNTGYCAYCARYTNGCNATHACNGTNGGNATHYTN TTYTCNCARGTNATGGGNYTNCCNGAYYTNYTNGGNACNATHGAYGGNTGGCCNTAYYTN TTYGCNTTYYTNGCNGTNCCNTCNYTNATHTGY--------------------------- ------------------------------------------------GGNTCNTGGATG TCNCARACNAARGCNATHTGYGTNGGNGGNGGNTAYGAYYTNGGNTTYATHGARTCNYTN GGNTCNTCNGGNATGMGNAAYATHMGNGAYTTYGTNAAYGGNGGNGGNTCNTAYYTNGGN ATHTGYGCNGGNGCNTAYTTYGCNAGYGAYTTYATHGARTTYGAYAARAAYGGNCCNYTN GARGTNGTNGGNGARMGNAGYYTNAARTTYTAYCAYGGNAARTGYATHGGNCCNGCNTTY CCNGGNTTYGAYTAYAAYTCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATHATGGCNAARMGNGGNCCNCARTCNGARYTNAAYGAYMGNAAYTGGGAYGAYGAR GARGARCCNGARGARGCNGGNGTNTTYAARCARGCNACNGCNGAYACNYTNCARGGNMGN GTNATHAARAARGCNAARMGNMGNGGNGCNGGNGARGARGGNAAYGGNACNACNGCNTTY GGNGGNTTYGGNGGNYTN---------GTNAAR---------------------ACNAAY YTNGAYTCNGGNTCNACNCCNATGTTYGGNTTYGGNAGYGCNGCNATHTCNTCNAAYGTN GGNTTYTCNTCNAGYATHAARAGYAGYACNTCNTCNTCNTCNTCNYTNTCNAARGAYAGY TCNTAYYTNCARGCNYTNAARGAYYTNAAYCARAGYGTNYTNGCNTGGATHAARCARCAY GTNGAYAARAAYCCNTAYATHATHYTNTCNCCNATHTTYAARGAYTAYGAYAARTAYGTN GCNAGYYTNGARTCNAARAARGCNGCNACNGCNACNACNACNGCNACNACNACNGCNTCN TCNTCNAAYGGNTCNAGYTCNGCNTTYTCNACNCCNGGNCCNACNATHTCNTCNGAYGGN AARGAYAARGAYACNGAYACNGAYGGNTCNACNAARGCNACNGGNGCNGCNTCNGCNTCN AAYGGNAGYGGNTTYAARTTYGCNGCNTCNACNACNAGYACNACNAAYTCNGGNTTYAAY TTYGGNAARGCNACNGCNCCNTCNATHTCNTCNGGNTTYTCNTTYTCNTCNTCNACNACN ACNGCNCCNACNACNGGNTTYTCNTTYGGNAGYGGNGGNYTNGGNAGYAGYAGYGGNGTN GGN------------------------------GGN------------GGNGGNAGYACN ------------------GGNGGNGGNTTYTCNTTYGGNGCNYTNGCNGCNGCNAARGCN GCNACNGAYAAR---------GCNCARGARGGNGGNGCNGGNGGNGAYGAYGAYGARTAY GTNCCNCCNAARCCNGARGTNAARGARATHAARGARGARGGNTCNYTNTAYTCNAARMGN TGYAARYTNTTYTAYCARAARGARGGNGGNTGGACNGARMGNGGNGTNGGNAAYGTNCAY GTNAARCCNYTNGAYGGNAAYAARACNCARYTNYTNATHMGNGCNGAYACNAAYYTNGGN AAYATHYTNYTNAAYATHAAYGTNACNTCNGCNYTNCCNGTNTCNMGNCARGGNAARAAY AAYGTNYTNYTNGTNTGYGTNCCNAAYCCNCCNYTN------------AARGARGGNACN ACNGAYCCNAARCCNATHTCNATGYTNATHMGNGTNAARACNGCNGARGARGCNGAYGAR YTNYTNGCNACNYTNGARCARMGNAARGCNYTNYTNAARTCNTCNGAYTGGTTYTCNCAY GGNAARGGNGCNAAYCCNCARCCNGARGCNMGNYTNMGNTCNGAYGCNGCNMGNGAYAAY GCNYTNAARAAYMGNGGNTCNGTNGGNGARAGYATGGGNGGNTAYGCNAAYCCNGCNCCN GTNMGNGTNACNCAYCCNMGNGGNGTNAARCCNGARGCNCARTCNAAYGCNTTYAAYAAY AARGGNGGNAAYATGAARAAYYTNATGGARAAYTAYGGNAAYATGACNGTNTCNCCNAAR CCNGARCCNAARGTNAARGGNAGYGARGCNCARGARTAYAARGARMGNGARMGNGGNAGY ACNAARGTNYTNYTNGAYCAYTAYAGYMGNGAYCCNGTNCCNGAYAGYACNATGCCNCCN CARCCNMGNYTNGGNYTNGGNGCNGGNGAYATHGCNGARAARCAYAARGGNGARCARATG GGNCCNYTNATGMGNYTNGARGGNAARAARACNCCNMGNTCNCCNMGNCARGGNCCNYTN CAYCARACNTCNAARGGNGCNAGYTGGGAYGARAAYCCNCCNCARAAYMGNAGYMGNCCN GARGGNGARAGYATHGCNCARAARAAYAGYGCNGAYTCNATGGGNGAYATHYTNGTNCAR AAYAAYGTNCCNGTNCCNCARYTNAARGARGGNAARGTNYTNAARCAYYTNCARCARTCN GAYATGTCNTCNCAYGTNCCNCCNCAYMGNGTNMGNAAYGAYGGNYTNCARAAYTTYGAR AARGCNAAYAGYMGNGARGARATGACNGCNATHATGAARGGNAGYCCNTCNGGNGGNAAY GTNMGNCCNMGNACNGGNAARAARGTNATGTCNCAYYTNCARAARTCNGARYTNTGG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNYTNAARCARATHGCNTTYMGNACNGTNGGN YTNYTNTCNACNGTNAGYGTNTGGTCNGTNAARCARCCNMGNYTNGARGTNMGNAAYYTN CAYGAYGCNACNGTNGCNACNGCNGAYTGYTTYACNCARYTNATHATHTCNGGNCARCAR GCNGARGTNYTNAARMGNGARGAYMGNTTYYTNTAYATHTGGGGNACNTCNGGNTCNGGN AARACNYTNYTNYTNGCNYTNAAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNAARTCNTCNCAYCCNAAYYTNATGTGYTTYGCNTTYTCNCCNCCNGGNGGNYTNATG AGYCCNTCNGCNAGYGCNTAYACNCARGAYTTYATHTGYTCNGTNGTNYTNGGNAARGAY YTNGTNCCNMGNYTNGGNATGTAYACNYTNYTNGAYYTNAARGTNAARATHYTNMGNGCN YTNTGYCAYTGYAAYCARCCNAARTAYCARATHYTNGCNTCNGGNTGYTTYMGNYTNYTN TGYTGYAARTCNTCNCARGARTCNGAYGARAGYMGNGARATGYTNGTNCCNMGNTCNMGN TAYGTNCARGAYCARAAYTGYATHATHGARGAYYTNTTYGTNCARGAYGCNYTNMGNATH GCNGARAGYAARATGGARGARATHGTNCAYACNGARTGGCCNYTNCAYCCNGCNGGNCAR ATHYTNCAYATHATGGAYGTNGGNGAYACNGCNTCNTGYGGNAGYAGYCCNATGTTYTGY GCNGTNTGGTCNAGYCCNGARTAYTTYGAYAARATHGTNATHAGYCAYAARATGGTN--- ---------------------------TCNCCNTTYACNCCNATGGCNCCNTAYGAYGAY ATGAAYACNCCNGARYTNAARAARGCNGTNTGYAARGTNGGNGTNAARCCNATGGGNAAR AARMGNATGMGNGARYTNYTNAARCAYATHTAYACNGARACNCAYCARTAYGARACNGAY ACNGAYGAYGGNGCNACNCCNACNAARMGNCCNAARGGNACNACNTGYCARGAR------ ------------------------ACNTCNAARAARCARYTNTTYTCNAARTCNTCNGAR ACNMGNAGYTGYCARAGYGGNYTNAAYAARATGMGNAGYGGNYTN--------------- ------------------------------------------------------------ ---------------------------------------GAYGGNMGNGGNCARCARACN GTNTCNAARCCNACN------------TCNGCNGTNTCNACNGCNCAYGTNYTNGTNCAR AAYGGNAGYGGNGAYGAYGAYGAYGAYATHYTNGGNTCNCARGAYTCNAGYTTYAGYGAY GGNCCNGAYYTNCCNGARGARAGYATHYTNCARGTNYTNCCNGARGAYGAY------GAY GARGAYATGACNCARYTNACNCARACNMGNATGGARGTNYTNAAYGARMGNYTNATGGAY TTYYTNMGNAAYACNCCNGARGTNTAYACNAARATHYTNATGTAYGARGCNYTNGARYTN GAYGTNYTNAARAARCARATHGCNGAYGCNGGNATHMGNATHGGNTTYCCNAARYTNCAR GAYTTYYTNGAYGARMGNTGYATHACNTTYTCNATGAARAAYATGAGYAAYMGNAAYAAY MGNCARAARAARAARGGNAAYTCNCCNGTNAARMGNMGNAAR------------------ ---------------------GTNAAYGGNATGAGYGCNAARYTNTGYGGNTGGYTNGCN ACNYTNAARGGNAAYATHYTNGAYGARYTNMGNGCNATHYTNGARGCNTCNCARGCNTCN CARAARCARGARYTNGCNMGNGCNAGYGARCAYATHYTNTCNGARAARTCNTCNYTNCAR AARGARGTNAAYAARYTNACNGARCARATHCAYGGNYTNGARCAYAGYYTNAARCARAAR TGYACNYTNGTNAARAAYYTNACNGAYTCNYTNGTNGCNCARAARAARMGNGTNGARGTN GCNAARCAYTTYTAYCAYTGGAARGCNGAYCAYCAYGAYAARCARMGNGARATHTTYACN CARAARYTNGCNGTNCARCAYCAYGARMGNAARYTNAAYYTNMGNGTNYTNAARGCNTGG TAYGGNATGATHCARACNMGNTGGMGNAGYMGNGTNGARMGNAARAGYCARACNCARGCN AARGARATGTGYATGACNYTNTCNAGYGAYTAYGARTCNAARGTNTCNACNYTNAAYGAR AARATHTCNGCNYTNGARAARAARGTNTCNYTNYTNCARGCNGARMGNGARATGTAYTCN GARCARGTNAARAARGCNTTYATGMGNGGNATGTGYGCNYTNAAYATGGARACNATGTCN GTNTTYGGNGARGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG GGNMGNAARAARATHCARATHGCNMGNATHAAYGAYGARMGNAAYMGNCARGTNACNTTY ACNAARMGNAARTTYGGNYTNATGAARAARGCNTAYGARYTNAGYGTNYTNTGYGAYTGY GARATHGCNYTNATHATHTTYACNAGYAAYAAYAARYTNTAYCARTAYGCNAGYTCNGAY ATGGAYAARGTNYTNYTNAARTAYACNGARTAYAAYGAYTCNGTNGTNAGYCARACNAAY AARGAYATHATGGAYATGYTNAGYAARAARGARAGYAARGGNGGNGAYTTYGAYGGNGAY GAYGAYGAYTAYCCNATHTCNCCNMGNACNGAYGARAGYTAYMGNAARATHGAYGCNGAR TTYGCNMGNGCNATGAAYGAYGGNGGNYTNAARACNTCNTCNGTNCARTAYCARATHCCN GTNCARACNCCNGCNGCNCARTAYACNGCNGCNCCNGCNAGYATGGCNAGYGGNGGNTCN GTNATHGTNYTNCARCCNGGNGGNMGNCCNCARGCNCARATHAGYACNTCNTCNGGNYTN ACNATHCARAARGTNCARGGNAGYGTNAAYGTNTCNAGYGCNGGNCARCARATHCAY--- ---------------------CCNGTNGCNYTNCAYGTNGCNGGNAGYGGNGAYYTN--- ATHGCNACNTCNTCNACNGCNACN------------ACNTCNACNGCNACNAARAARCCN GGNYTNAARGTNGTNATHCCNGAYMGNGCNCARGCNGTNGTNCARACNAARGTNCAR--- GGNACNGCNYTNGAYACNCCNAAYGTNTCNATHGCNACNCCNAAY---AGYCARAAYGCN CARGGNACNATHCARGCNATHYTNCARTCNGGNGAYYTNYTNAAYAGYGCNGAYATHGCN GGNYTNTCNCCNYTNGTNTAYCARYTNACNAAYCARGGNCCNGGNCCNGGNCCNYTNACN GCNGCNYTNCARGCNTCNGGNGTNTTYACNCCNGGNGGNTCNATHTCNATGTCNACNACN CCN---ATHATHACNYTNCCN---GCNCAYAARCCNGGNGARYTNGTNAARCARGARCCN CCNGGNTCNCCNAGYAARCARGAY---GTNCAYGARGGNCCNTCNGTNACNCCNCCNCCN GCNGCNAAYCARGGNGARCCNCCNGARAARMGNCARMGNTTYGAYACNGAYATGAGYTCN GAYACNTGYTTYAARTGYGGNGGNMGNGGNCAYTTYGCNMGNTAYTGY------------ ---GGNACNGGNGAYCCNGGNMGN---------------------------------GGN TTYTCNGCNCARAARTGYTTYAARTGYAAYMGNATGGGNCAYTTYGCNMGNGARTGYACN CARGAYCARGAYMGNTGYTAYAARTGYAAYGGNYTNGGNCAYATHGCNAARGAYTGYGAR AARCARATHTCN---ACNGGNGCNTGYTAYAAYTGYGGNAGYAGYGAYCAYYTNCARMGN GAYTGYCCNGAYGCNATHATHAARTCNTGYTAYMGNTGYGGNGAYTCNGGNCAYYTNGCN AARGARTGYCCNGCNGARATHCCNGGNAARCCNTTYGCN------------GAYGAYMGN AARTGYTAYACNTGYGGNGGNATHGGNCAYYTNGCNAARGAYTGYCCN------------ TCNCCNMGNAARGARTGYTAYMGNNNNNNNNNNNNNNNNCAYYTNCARAARGAYTGYCCN AAY------GARTCNGAYGCNGTNTGYTAYAAYTGYAAYAARGGNGGNCAYATHGCNMGN GAYTGY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATHYTNGCNTCNCCNCCN YTNCCNCCNCCNCCNTCNTCNGARGTNCCNGAYCARTTYGAYTAYCCNGCNCCNCCNCCN CCNCCNGAYTTYAGYGAY---GARGGNGGNCCNCCNAGYATGMGNGAYGGNGTNCCNCAR CCNYTNGARAAYGAYATHTAYGGNACNGCNCARGGNATHGGNGAYGAYCCNTAYGCNGCN ACNGGNCCNCARTTYYTNGCNCCNACNACNTGGATHCCNAARCAYTAYYTNGARAARGTN GTNGCNATHTAYGAYTAYCARGCNAAYAARGGNGAYGARYTNTCNTTYGCNGARAAYGCN ATHATHTAYGTNATHCAYAARAAYGAYGAYGGNTGGTGGGARGGNGTNATGGAYGGNAAR ACNGGNYTNTTYCCNTAYAAYTAYGTNGARCCNTGYATGAARMGNTAYYTNATHATHACN GCNGAYGAYTTYGGNTTYAGYAARGARMGNAAYGARGGNATHATGGARGCNATHAAYATH GCNGGNGTNAARAGYACNTCNYTNYTNYTNAAYTGYACNGGNACNAAYGAYGCNGTNCAR TTYATHMGNCAYAGYTGYYTNGCNCCNGGNYTNCAYYTNAAYYTNACNGARGGNCAYGCN YTNAGYACNACNGCNCAYTCNACNYTNACNGAYCCNAARGGNGARTTYTGGGGNAARTTY GARYTNMGNAARYTNYTNGAYGGNGGNCARATHAAYCCNAAYGARGTNAARMGNGARATH GCNMGNCARATHGARGTNTTYAARGAYYTNGTNGGNAARYTNCCNYTNTAYGTNGAYGGN CAYCARCAYATHCAYGTNCAYCCNGCNGTNGTNGAYAGYTTYGCNTCNACNYTNCARGCN TAYGGNATHCARGGNACNMGNYTNCCNGTNGARYTNTCNATGGAYAARAARCCNTGGGTN CCNTCNGCNMGNAGYGCNTTYTAYAAYACNGTNATGGAYGAYGCNGTNAARTGYAARCCN GTNYTNGAYGCNTGYGAYATHMGNTAYTCNAAYGCNTTYGTNGGNYTNTCNACNATGGGN GCNGAYATGACNYTNGCNMGNYTNCARAGYGGNATHYTNCARGCNTTYGARAAYGCNGAY MGNMGNTTYGTNGAYAARTCNACNACNACNACNACNTGYGARYTNATGTGYCAYCCNGGN TAYGCNACNGGNAARGARGCNGGNGGNTTYAAYGGNMGNTCNGAYCCNTTYGGNTGYTCN AGYGAYMGNGARCAYGARATHYTNGTNYTNAGYTCNAARGARATGTTYGAYTTYTAYGAR MGNAAYGAYATHACNYTNGCNTCNCAYGCNGTNYTNYTN--------------------- ------------------------------------------------------------ ------------------------------------------CAYATGYTNAARACNGCN TCNAAYGAYGARTAYATHGGNAARATHMGNAARMGNYTNCARGARGAYGCNGCNGCNMGN GARGARMGNGARAARMGNMGNMGNAARGTNYTNGGNGAYCARATGAAYGCNCAYCARGCN CARGARGARGCNMGNMGNGARGARATGATGGTNAAYMGNYTNATGMGNCARTCNCARCAR GARMGNMGNATHGCNGTNCARYTNYTNCARGCNMGNCAYGARAARGARGTNATHMGNCAR AAYMGNATHYTNMGNGARAARCARTAYCARGARMGNMGNCARAARGAYTTYGAYGAYGCN YTNGAYYTNGARGCNGARATGTCNGCNYTNCAYAARATGGARTAYGCNGARCARATHAAR CARGAYCARGARYTNCAYGAYCARYTNGCNGCNCARMGNGCNGARCARMGNTAYAARAAY CAYTAYGAYATGTGYGCNCARATGGTNGGNAGYGTNGTNGAYTTYTCNTGYAARATHGCN GARTAYMGNGARYTNACNGCNAAYYTNYTNCCNCCNAARYTNATGMGNGARTGGAARYTN YTNTTYACNAGYGGNCARCCNYTNTTYGARGCNGARGARGTNGTNAGYACNGARYTNACN CCNGARCARGTNYTNGARGARGAYMGNCARCARYTNYTNGAYGARGGNGAYTTYATGGAR TAYAARGGNATGAAYGGNGARTGGGTNCCNCCNGARGARGGNGARATHACNGGNCCNCCN MGNGAYAAYCCNGTNGTNCCNCCNACNCCNCCNCCNCCNACNCCNGARCCNGARCCNGAR CCNGARYTNGARGARCCNACNGGNCCNCCNCCNCCNAARCCNGGNGAYGARGARTGGGAY TTYGTNGAYYTNGAYYTNGAYAAYGARYTNGCNAARGTNYTNGTNYTNCAYTGGGARGAR ACNGARAARACNTAYGTNAAYGGNTGYAARCAYGTNTTYMGNAAYATHMGNGAYGARMGN GARAAYATHTAYMGNTAYTTYTTYCARATHMGNAARGAYTTYYTNCAYTAYYTNMGNMGN CCNGAYTGYAARCARGAYTAYGTNTCNCARTGGCARAARTCNTAYAAYGARGTNTCNGAY GAYATGMGNGAYGAYGARGARACNMGNGCNGARYTNCAYCARCARGTNGAYGAYYTNMGN GARMGNYTNTGGAAYGTNTGYGAYGAYMGNAARGARCARGCNGARMGNGARMGNGARACN AAYATGAAYGAYGGNTGGYTNGARGAYMGNYTNGGNATHYTNAGYAAYCAYTAYYTNACN YTNATGCARGCNGARGTNGAYMGNYTNCARGAYACNGTNMGNATGYTNAARGAYTAYTAY MGNGGNATGGAYGGNAARGTNCCNGAYGARYTNAAYCCNGAYTAYGARMGNGTNCCNYTN ATHGARYTNCCNGTNGARMGNCCNGARACNCCNGARGGNACNMGNAGYGARACNGCNCAR TCNCCNGTNGAYGAYGCNAARTCNGAYMGNTCNGCNTCNGCNMGNTCNAARTCNCCNAAR GGNGGNMGNMGNTCNAARTCNCCNAARGAYMGNGCNAARTCNCCNAARGGNTCNMGNTCN TCNMGNACNGCNTCNGGNAARAARAARAGYAARGGNGGNAARGARACNCCNCARCCNGAR GCNCCNAARTCNTCNGARGGNATHGGNMGNMGNATHGTNATHCCNYTNGTNCCNMGNMGN CCNGTNTCNCCNGAYGGNGARATHAARGTNGGNGCNACNCCNTCNAARGARAARAARGAY AARAARAGYGTNAARAARGGNATGTCNGCNACNGAYGAYYTNCCNGGNACNGARAGYCCN GCNCCNCCNCARGAYYTNGAYGARAARYTNATHTAYGAYGGNTTYACNTTYGCNGTNACN GGNATHACNCARATG---CARTGYGARATGCARGCNMGNGARGCNGARGARGARGCNGAR MGNYTNAARGARCARGARAARGARAARGARAARGARAARGCNAARGGNGCNAARGCNGCN AARGGNGGNAARAARGGNAARAGYMGNAGYCCNAGYCCNAARAARGGNGGNAARGGNAAR GAYTCNGARTCNTCNGCNACNCCNCCNCCNGCNCCNTCNGARATHAGYGARGARGAYCAR CARMGNAARTCNTCNAARGARMGNGCNMGNGARGARTAYTAYTTYTCNATHCARGARGAR GARCARGCNGCNAARATHMGNYTNGAYYTNATHMGNATHYTNGCNTGYGCNATHYTNCAR GAYYTNAARTCNAARGGNGARGARGCNTTYAARGAYATGAAYGAYTGGYTNGGNGCNMGN TAYYTNAARGARATGGARAGYATHGAYCARATGTCNGARGTNGTNMGNAAYGCNATHGAR ATGAARGARAARYTNACNAARGARGTNYTNYTNGARCARGAYAAYTTYATHGTNGAYGAR GAYYTNAARGTNYTNMGNACNCCNAGYCCNCCNGCNCCNCCNCCNCCNGTNGARCARCCN ACNGCNGARCAYTTYACNGTNAAYCARYTNACNTCNYTNTAYGARCARTTYMGNTCNTCN GCNCCNACNGGNATHATHTCNAAYAARGCNTTYGTNGARATGTTYGARAAYATGGTNTCN GTNACNCAYGGNATGGARACNYTNCCNGAYGTNTGGACNCAYYTNTCNCCNTCNCARATH CARGARYTNGCNTCNATGYTNTCNTCNGARACNGAYTAYGTNGAYTGGMGNMGNYTNYTN GTNGCNYTNTGYCAYCCNATHCCNACNCCNACNCARCARCARYTNYTNGAYTCNYTNGCN AARTTYAARGAYATGGAYCARAARGAYACNGGNAARGTNACNMGNGARCARTGGCARMGN ATHCCNYTNTGGTTYGAYATGGARCCNCAYTAYGAYYTNGCNTAYAAYMGNYTNGCNAAY YTNCAYCCNGCNYTNTTYGARATGTTYGCNGAYCAYTCNGGNTCNATHTCNCARYTNCAY TAYAAYAGYTTYYTNATGTAYTTYTCNGCNGCNGCNAAYTAYCAYGARGGNTTYYTNMGN GCNYTNAGYATHGCNTCNMGNMGNCAYATGCCNMGNYTNGGNAARCCNTCNYTNGTNTCN CARACNACNCARYTNGGNGARMGNGCNTCNAGYGCNATHGAYAGYTTYATHCARGARGGN ACNGARTAYAARGAYGAYGAYAARCCNCCNTCNGARCCNCCNATGTCNGAYGARGTNATH CCNCCNGARGCNAAYGAYGCNGTNGTNTCNGTNGARGCNYTNTTYCARGTNYTNCAYCAY GGNGARATHTCNAARGGNGAYAGYCAYMGNTTYAGYGTNACNGCNGAYCCNGARGARCAR ACNTCNTTYGARMGNYTNAGYGCNGTNTTYCARGARYTNAAYGARGAYGAYAGYACNTCN CCNATHYTNTAYAARATHYTNATHGAYCAYCCNYTNATHCARGAYGTNGTNGTNGCNTGY AARCAYTTYAARGCNYTNGAYATHAARGGNYTNATG---TCNTCNTCNCAYGAYGTNGCN GARATHACNAGYYTNAARACNATGGAY---------TTYGCNACNTTYGARGAYYTNAAR TCNGCNGTNTCNGARTGGGGNAARTGYGARAAYAGYYTNTTYGTNATGGGNGAYTCNAAR AARTCNAARTCNAARTGYCAYGAYGAYGGNTCNGTNATHTAYGARTAYYTNYTNTTYGTN TGYAARCARGGNGGNAARAGYMGNCCNAGYMGNAGYMGNGGNYTNMGNCCNAAYCARAGY ACNMGNAARTGYGGNTGYCCNGTNAARGTNMGNGCNACNGCNTCNYTNACNGAYGGNGTN ATGGGNTAYAARATHACNCARYTNTGYYTNGARCAY---AAYCAYGTNACNTCNGARCAR ATHTAYCARACNTAYCCNGARATHMGNMGNCAY--------------------------- ------------------------------------------------------------ ------------------------------------------------ATHGTNGCNCAR MGNYTNMGNCCNGTNGTN---YTNMGNYTNCAYGTNAAYGCNGGNAARTCNYTNCAYACN ACNCCNMGNMGNCAYGGNCARGCNATGTAYMGNGARAARATG------TTYGARTAYCAR GARCCNAARTAYATHCARCAYGCNGGNACNGCNTTYAGYGCNTTYATGTGGTAYTGGATH YTNTAYCAYTGYTAYTTYGARTTYGGNCAYYTNGTN------------------------ ---------------------------------------------TTYYTNAAYAARYTN GGNGARATHCCNGTNYTNAGYGAYGGNTGGTTYGCNGCNGCNGAYTAYTAYTCNMGNGTN AARGAYTAYAAYGCNYTNATGMGNATGACNYTNTCNATGGCNGARTCNGGNGTNAARGTN GCNGGNCAYYTNTCNACNCCNGTNTTYAAYCAYTAYCARCCNCARATHGAYAAYYTNAAY GARTAYGCNTGYAARACNYTNGAYGAYYTNGARACNAARTAYCCNGTNATHAARCARCCN ACNGARCARTGGAARGGNACNTGYGCNGAYYTNGTNGARCCNGTNGTNGGNMGNGTNAAR CCNATGATHTCNCARGTNCARGGNATHGTNGAYAAYGGNAARCARAARATHAAYAAYATH AARACNGCNAGYACNAAYATGATGGARGGNGCNAARACNMGNGGNGTNGGNACNGTNACN CAYGTNGTNAAYTCNACNTTYGARACNGTNCCNGGNMGNTTYGTNACNMGNACNGTNGAY AGYGCNYTNGAYATGGCNGAYAGYYTNGTNGAYMGNTAYYTNCCNGARGARCARGARGAR ACNGGNGARCARCARGAYTCNTCNGAY---GARGARTGYTCNGARAAYGCN--------- ------GGNTCNCARGTNGARAARATGGARGARATGAAYCCNAGYCCNAARMGNGTNYTN GTNCAYGCNACNTGYATHACNGARAARATHMGNAARMGNATGTAYMGNMGNGCNATGAAR GAYATHACNTAYGCNMGNGCNMGNACNACNGCNGCNYTNAARAARATGACNAGYACNGTN GARYTNATGGAYYTNGCNAARAAYAAYYTNAAYACNGCNAARGARAARGTNGAYAAYATG TGGACNGAYATHGTNAARGAY------------TCNGAYGTNGCNGAYGARAARACNGTN TTYGTNGGNACNGTNGARGGNMGNATHGTNGCNYTNGGNMGNATHYTNGCNMGNCARGTN AARTCNGGNGTNACNGCNTTYGARAARGCNTAYTCNGARYTNGGNGARTTYAGYAARAAY CCNATHTCNAARTCNAARGARTAYAARGAYYTNATHGCNACNTTYYTNTCNGTNGARTCN ATHAARAAYATHTCNTCNCARAAYYTNCARAARGCNMGNGARTCNYTNAARTAYYTNCAR GAYMGNATHACNAGYATHTCNCCNTCNYTN---------AGYTGGGTNGCNGTNGAYATH AAYATGGARAAYATHCCNATHAAYGARACNGAYYTNGAYMGNMGNGTNCCNYTNACNAAR AARGARGTNTTYTCNYTNYTNCARTCNTGGMGNGGNATHMGNMGNMGNATGGARGAYGCN GGNGTNGARATGTTYGTNMGNYTNTTYAARACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AGYGGNYTNAAYAAYGARGARGAYGCNGCNTGYYTNGARYTNYTNATHAAR GCNTCNGGNCARTTYGAYYTNACNAAYYTNMGNGGNGGNYTNYTNCCNATGATGGCNGGN GAYAAYMGNYTNCAYGARATHYTNAAYCCNYTNGTNAAYTCNCCNMGNTCNYTNYTNGAR CARTGYMGNAARMGNATHMGNCAYAGYATHGGNCARCAYTTYYTNCCNCAYGTNGTNTCN AAYYTNCCNYTNCCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CAYAGYGGN AARGTNTGYAARGTNAAYACNGARTGYCARCARGGNGARTGYTGYCARATHATGAGYCAR TTYYTNGTNGTNAGYAARMGNAAYGGNTTYTCNCCNTTYYTNGGNTCNGGNGCNACNAAR GARMGNACNGGNACNTGYGARCCNTAYMGNYTNGARGGNGAYTCNTGYTCNCCNTTYGCN AARMGNAAYGGNTTYTGYAGYTGYGARCCNGGNACNAARTGYAARAGYTTYGARGTNCCN TCNTCNGCNGARTCNCCNMGNYTNMGNMGNAARATGYTNMGNCCNMGNCCNGGNTAYATG TGGATHCARAARTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ACNGCNTTYYTNGGNGTNYTNGCNYTNYTNYTNCCNGGNGTNTCNGCNGTNAGYGAYTAY GTNCCNGTNATHGCNTCNGGNGCNGTNGCNYTNTTYYTNYTNYTNATHYTNATHGTNGTN ATHGTNTTYGCNTCNTGYTTYGCNCARACNTGGATHAARTCNAGYATGMGNAAYGAYGGN AARGTNAARATGCCNMGNTCNTAYTTYGCNAARAARAARGARGCNAARMGNMGNYTNYTN GCNGARTCNGTNMGNTCNTCNTCNCARCCNATGGTNAAYGGNAAYCCNCCNGCNATGCCN ATGGAYAARGCNCCNAARMGN------GARACNYTNGTNGARGGNTGGAAYCAR------ ---AAYACNMGNMGNATHTAYGARGARAARGGNTAYACNYTNGARATGGGNGAYGARCAY GARGARGARTTYCAYATHGARACNACNATHGTNGAYAAYGARGTNYTNGAYGTNGGNCCN TAYMGNAAYYTNGGNTCN---TCNAGYGCNMGNCCNGTNGARGGNAAYGTNTAYAAYAAY CCNTAYYTNTAYACNAAYAAYGAYMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GGNGAR GGNCCNCCNTCNGGNGGNCCNGGNCCNATGATGGGNGGNAAYGCNYTNGGNYTNMGNGAY ACNCARYTNGCNYTNGCNCARTCNYTNYTNCARCARCARCARYTN---ATGAAYTCNGGN TTYGGNGGNGCNGGNGGNGAYTTYGGNGGNYTNGGNGCNYTNGCNGGNGGN--------- ATGCAYTTYYTNCARCARCARCARAAYCARATGCCNYTNGGNGGNGGNGGNGTNGGNGGN YTNGGNATGGGNGGNGGNATGMGNGGNGAYMGNAARMGNAGYGGNGGNCARYTNMGNMGN GAYAAYGAYGARAARMGNGGNMGNMGNGAYTCNTGGGGNMGNGGNGARMGNGAYMGNTCN ---------CAYGGNAGYAGYAAYMGNAGYGGNCARGAYMGNGAYMGNAAYMGNMGNGAY TCNGAYAARGARAAR---AARAARCARGGNGARGAYTAYGAYCCNGCNGARCCNACNGAR GAYGAYGAR------AARGARAARGAYAARGAY---AGYAAYYTNTAYTGYCAYGTNTGY TCNGTNTCNGTNTAYGAYGARGARAGYTTYCARMGNCAYYTNAAYGGNYTNAARCAYAAR TCNMGNATGGARAGYATHGCNTCNGTNCAYAAYGTNMGNAAYTCNCARATGAAYTTYMGN YTNAARGCNGARGARCAYYTNMGNAAYATHGARMGNAARGGNGGNMGNGAYCCNGAYTAY TTYTGYAARATHTGYAAYAAYGAYYTNGCNATHCCNTGGGARAARCAYMGNTAYTCNAAY ATHCAYAARCARMGNYTNYTNCARGTNMGNAARGGNTGYGGNTGGTGYAARGTNCAYGAY TTYACNAAYTTYACNGARGTNYTNGARCAYMGNGARACNGAYGARCAYAARAARAAYGCN GARYTNTAYGGNAARAARGAYGAYGARAARGAYGAYTCNMGNACNMGNATHAARGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARATHGGNGGNCAR CCNGTNTGGATGTCNAARTCNGCNYTNCCNGCNATHCARCAYTGYCARTGYTGYTCNACN GCNYTNACNYTNGTNGTNCARYTNTAYTGYCCNYTNTCNAAYTCNGCNTAYCAYMGNTGY YTNTAYYTNTTYGTNTGYGCNTCNTCNMGNTGYCCNCARTAYAAYAGYTGGAARGTNTTY MGNAGYATGCARTAYGAYGARGCNTAYGCNCCNTGYAARAGYGARMGNAARAARGAYGAY AGYTCNGAYATGTGGGCNGAYGAYCARGAYGAYTGGGGNGAYATHGTNTCNAAYGAYAAY ACNAGYMGNYTNGAYCARYTNGCNTCNGTNYTNAAYACNAARGCNGARTCNTCN---GTN GTNGAYGAYCARTCNTCNTCNMGNMGNCCNYTNCARYTNAARCCNTAYTTYYTNTCNGTN GTNGAYGGNACNTTYCAYAGYTCNTGYCAYGCNGTNGAYGAYGGNCAYATHGCNAGYYTN ATHMGNGARTAYGARGARGTNGARGGNMGNCARATGAARGAYATHATHAGYGAYMGNGCN CARACNGGNAARGGNGCNTCN---GARGGNTAYGARAARTCNAGYGTNAARCAYGGNGAY AARGTNTTYCAYAARTTYTGGAARGARATHMGNAARTTYCCNGARCARTGYATHMGNTAY GAYMGNGGNGGNGAYCCNYTNYTNGTNCARAGYYTNAGYCCNGTNCARGCNGTNATHCCN CCNTGYTCNAARTGYGGNGCNTCNMGNGTNTTYGARYTNCARYTNGTNCCNGCNYTNATH CCNTGGYTNTGYTCNCARGARGGNAARCCNTCNGGNGGNTGGYTNYTNTAYAARTAYGTN YTNMGNAARATHCARGARATHMGNGAYGCNGARGAYAARMGNTAYYTNATHTAYATHAAR MGNCARCAYCAYTTYGAYAGYAAYCARMGNACNTGYAAYATGACNGTNYTNTCNATGGTN CCNAGYATHMGNGARGCNYTNGTNAARCAYATGGAYGTNGAYGCNGTNAARGARATGYTN AARTCNAAYCCNTCNAAYAARYTNGARYTNTGGGARGARYTNAARATHATGAGYGTNACN MGNTCNATGGCNGCNGTNTAYGGNACNTGYATGYTNTCNGTNATGYTNMGNGTNCARYTN AAYGTNATGGGNGGNTAYYTNTAYYTNGARAGYYTNCAYCCNACNAAYGARCARGGNGTN GGNGAYTCNAARAAYAARMGNATHCCNCARAARGTNCARGARMGNTAYYTNTCNGTNGTN AARGARTTYATHGARCARGGNTTYYTNGAYTTYATHCAYGGNYTNAARYTNGCNGTNATG AARGARTTYGGNAGYATHTCNYTNAARGARAGYYTNGGNYTNGAYAAYATHGCNTCNATH TTYGGNCAYGTNMGNGARMGNATHGARTGYGGNGTNGAYAARCCNACNATHTCNYTNTAY CCNTAYYTNATHAARTGYGARCARGTNCCNGTNCCNGAYTCNCARAAYGCNGTNAAYCCN GARGAYGARYTNTAYGARAARYTNATHTGYGARACNMGNGAYATHYTNGARAGYTAYGAY TTYCAYTCNGTNYTNMGNTCNAGYATHGAYMGNGGNTTYAAYTGYATHATGGAYACNYTN GCNGAYCAYTTYAARCARGTNTCNGGNCAYAAYYTNGAYCAYTCNAGYATHCAYGAYYTN TCNATGGCNATGGCNAARYTNATHCCNGTNYTNAGYGCNYTNYTNCCNAARATHTGYGGN GAYGCNCCNAAYCCNTTYATHCARGARYTNYTNATGATGGARGARYTNAARCARYTNGCN GCNAAYGTNTAYGARGCNTTYAGYCARGAYTCNATHAAYACNCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYCCNGAYGGNAAYGAYTAY TTYTTYMGNAGYTGYAGYMGNMGNATGAGYAAYYTNCCNYTNCCNGCNCARTCNYTNYTN MGNYTNCARATHACNCARYTNTTYTTYAAYGCNGARAAYCCNGAYATHGCNGAYGTNGAR ATHACN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGGCNGCNACNAGYYTN AGYATGGAYAAYCCNGTNTTYMGNTCNTTYGTNGGNTAYGCNGCNGTNGTNYTNYTNAAR ATGATGYTNATGAGYYTNATHACNGCNTAYTAYMGNATGACNAARAARGTNTTYGCNTCN GARGARGAYYTNGCNTCNTTY---------AARACNAARAARGTNATHYTNAAY---GAY ---CCNGAYGTNGARMGNGTNMGNMGNGCNCAYYTNAAYGAYYTNGARAAYATHGTNGCN TTYGTNYTNYTNGGNGCNYTNTAYTGYACNACNGGNCCNGCNYTNTCNACNGCNYTNATH CAYTTYMGNGTNTTYGTNGCNGCNMGNATHATHCAYTCNATHGTNTAYYTNTTYGTNGTN CCNCARCCNGCNMGNGCNYTNTCNTTYATGGTNGGNTTYGGNGTNAAYGTNTCNYTNGCN GTNMGNATHATHATGCARGCNGCNTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARCARCCNGAYCAY MGNCCNTGYACNYTNAGYYTNATHCAYGTNMGNYTNCCNCCNGGNTTYTCNGCNACNTCN ACNCCNGARMGNCCNACNAGYGTNCAYACNGCNTTYTAYAARAAYGAYACNTTYATGYTN GTNTCNTCNCARAGYCARGAYMGNGAYATHYTNTGGTGYGTNAGYCCNGAYTCNTTYCCN TTYCARAARCARYTNATGGARGCNCAYACNATHATHTCNTCNGGNGGNAARACNTGGGCN ATHGARGARGTNCCNTCNMGNTCNGTNAAYCCNYTNTCNGCNACNTCNTCNCCNATGMGN CARGTNACNGAYCCNCCNTGYGTNGTNACNCARCAYGCNTTYCCNCCNMGNMGNTTYGTN GTNYTNAGYACNCAYGGNGTNCAYATHGTNCARAARYTNMGNCCNGTNGARCARYTNAAR GCNYTNYTNYTNGARTGYGGNGGNCAYGAYTCNGARCARGTNAARGCNTTYTTYMGNYTN CAYAARYTNGAYCARGCNTGYGCNATHTGYYTNGTNYTNGCNTGYTCNMGNGCNGCNGCN GAYCARCARGTNTCNAAYGGNGCNMGNATGGCNTTYTTYATGTAYGGNGGNGARGCNCAR TGYAAYTTYGCNGGNYTNMGNCCNGGNATHGGNAGYCCN------------YTNCCNGGN ATGTAYAGYCCNGGN------ATGATHCCNAAYAGYCCNYTNCCNAAYATGYTNACNTCN ACNCCNGCNCCNGGNGCNATGYTNGGNTCNCCNGTNGGNGGNGGNAGYCCNAAYACNYTN CARCARGARGTNATHTAYTCNGGNAARCAYAAYGGNATHTAYATHTTYTTYAGYMGNATH ATGMGNCCNTTYTGGGAYTAYCCNGTNACNACNGARTTYATHCAYAAYTCNAARCAYGGN AARGTNACNTAYYTNACNTCNAAYTTYACNGTNGARGARYTNMGNACNGCNYTNGARATG GTNMGNGAYYTNTCNGAYTTYGTNGAYTTYAAYTCNAARTTYGAYGTNGAYTCNCARTTY GAYATHATGAAYACNGGNMGNGGNMGNYTNGAYGGNAGYATHGAYGARCARAGYMGNAAR MGNATGCARYTNGARGTNCARMGNATGGARAARATHTCNYTNCARCAYYTNCARGAYYTN YTNCAYMGNACNGARGARGTNYTNGGNYTNTGGTGYYTNYTNATHGAYCAYCARTTYCAY ATHYTNGCNGCNGCNATGGCNCCNGAYATHCARAAYCARYTNMGNAAYATGACNTTYAAR AAYYTNGTNACNAGYGGNAARGAYGTNTGYAGYACNYTNATHATHTGYYTNGTNAGYMGN TAYYTNAAYGAYAAYGCNACNATHGAYGCNATHAAYGAYMGNYTNMGNGARGTNTGYCCN ACNYTNTAYAGYACNGAYGAYGCNACNTGYTCNAARTCNAAYGARYTNYTNCARGCNGCN AARATHAAYCCNAAYAARYTNGARAARGARCARCARYTNCARGARGCNYTNCARYTNYTN AARGGNGTNTCNCARCCNYTNAAYYTNTCNGTNATHTGYTCNCARYTNGCNGGNGTNCAY TTYTAYYTNGGNGTNGTNGARYTNGCNYTNAAYGARGCNGGNAARYTNGAYCCNCARGGN ATGGCNATHCAYTTYTAYAAYAGYGGNGARCCNCARGAYGAYATHCARGGNATGCARGCN TAYATHGCNMGNATGGAYTGYTAYAARTGYATHACNGARACNYTNTCNTAYYTNAGYGCN GCNAGYAGYAGYCARGCNCARGTNCCNAAYAAYCCNTTYATGGCNTCNTCNACNAAYCCN GTNGARCCNAAYMGNATGGARCCNCARCARGCNGARTAYTTYMGNGARGARGTNTTYAAY ACNGCNYTNMGNTGYGAYGAYTCNYTNTTYCAYGCNTCNYTNTAYGARTGGYTNTTYAAY ACNAAYCARGCNGARAARYTNYTNGARATHAAYACNCCNTTYGTNGARCARTAYYTNMGN MGNAARGTNAAYYTNCAYACNGAYAAYACNGGNGCNYTNGAYATGYTNTGGMGNTAYTAY GARAARGTNGARAAYTTYCCNGCNGCNACNMGNATHYTNTCNCARYTNGCNGARMGNCAY GGNACNAAYGTNAAYYTNACNCARMGNYTNGARTAYYTNTCNMGNGCNGTNGTNTGYGCN AARAGYTCNACNTCNMGNYTNGGNACNTCNGCNGGNGGNGARACNYTNCAYGARYTNGAR GARAARATGGARGTNGCNMGNYTNCARATGCARATHTAYMGNTGYYTNTGYAAYATGATG ACNTCNCCNYTNGTNGARAAYGCNAARGCNMGNYTNGAYGCNGARYTNYTNGAYATHACN ACNYTNTAYGARGARTTYGCNGAYCCNTTYGAYYTNCAYGARATGAARYTNGCNATHGTN CAYTGYGCNGGNYTNTAYGAYGCNGCNYTNATHGARGAYYTNTGGMGNAAYATHATHGAY AARGARATHAGYAGYACNACNCARATGTCNGGNTCNGAYMGNATHAAYACNATHGCNTCN AARYTNTCNACNGTNGCNAARTCNTAYTCNAGYGCNGARMGNTAYTTYCCNGTNGCNYTN ATHYTNMGNCAYATGGARGARAARTCNTGYGARYTNGCNYTNGAYYTNGARTGGGTNTTY AARATGATGYTNGAYGTNGGNGTNGCNCCNGCNMGNYTNYTNGARYTNTAYGAYMGNYTN TAYAARTCNAARGAYGTNGTNTGGCARACNYTNGGNMGNCCNYTNCAYGTNYTNYTNGCN YTNCAYACNTTYATHGAYCAYYTNGCNMGNAAYCCN---GTNYTNYTNAARACNGTNAGY CCNCCNATGCARGTNTGGTGYYTNGAYYTNGTNGAYTCNTAYYTNGTNGAYYTNGGNGCN YTNGGNACNTCNACNMGNGAYGTNGCNCAYYTNACNGCNAAYTTYMGNGCNACNAARGCN AARYTNGAYMGNYTNYTNGGNGARATHATHGAYCARGTNGARAAYTCNAGYGGNAAYGAR AAYYTNYTNYTNTAYACNCCNACNACNCCNAGYCCNGARAAYGTNAAYTGYATHGTNGAR ATHCCNGCNATHMGNTAYGTNGGNGGNMGNTGYGTNAAYATHGGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNAARGAYTTYAAYGTNCCNATHACNCAYGCNAARGGNMGNGCNAARGTNMGNGARATG TTYATGAARAAYAARCAYGTNACNGAYATHMGNGTNATHGAYATGYTNGTNATHAARGGN CARATGGARYTNGTNGARACNGCNAAYATHTGGAARCARMGNCAYCAYATHATGGCNTAY TTYAARGAYACNTAYAAYCCNAARCCNACNGAYTTYYTNAGYAARTTYTAYGARGGNCAR GARGAYYTNAGYGARTCNTCNATHGARTGYYTNYTNGARCARYTNATHCARMGNGGNAAR ATHCARAARGCNTTYGTNATGAAYAAYGAYGGNGTNATHYTNGCNMGNAGYAARGCNTCN TCNGCNCAYGTNGCNAARTGYTTYTAYGAYAGYYTNMGNGGNCAYTAYGGNYTNATGAAR ATHGAYTGYCARGAYGGNCARGTNTAYGTNTGYTTYAARTCNTCNAGYGAYGGNGCNATG GTNGGNACNAGYGCNGAYTAYGTNACNGTNTGY------------------ATGAAYTCN GGNGAYAAYATHTAYMGNMGNATGTCNGGNCARCCNYTNTAY------AAYCAYATGGAY CARGARYTNGAYCAYAARGTNMGNAARGTNTCNGAYAARTTYTCNGARACNGTNAAYATG GTNGCNAAYGARCCNTCNYTNGCNTTYTTYMGNATHCARGARCAYGTNMGNAARACNYTN CCNCARYTNGTNGAYACNAARCAYGARGTNGARGAYGTNCARTCNMGNGTNCARGGNGCN TGYTTYGAYGCNGAYTAYGCNGTNAAYGCNGTNAARGCNATGCARAGYAGYGCNATHCAY TTYCARAAYATHCARGAYYTNYTNAARAAYGCNATGTTYATGAARCARCARATHACNTAY GARGAYAAYAARMGNAARCARGGNMGNAGYAGYCCNATGGCNGGNGARMGNAARTTYCCN YTNCCNCCNTGYMGNGTNTGYGAYGCNCCNGGNACNGGNTTYCAYTAYGGNGTNAAYACN TGYGARGCNTGYAARGGNTTYTTYCAYMGNAGYYTNAARCARTGGACNAARTAYAARTGY GTNAAYAARMGNAAYTGYGTNATHCARCAYGGNAGYGGNGTNYTNTGYMGNYTNTGYMGN TAYCARMGNTGYYTNGTNATGGGNATGTCNAARCARGCNATHAARACNGGNMGNTAYAAY TAYCARAARAARACNGAYGAYATHYTNGARGTNAARCARYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYGCNTGYYTNAARACN GARGARGARATHGCNGARGARMGNAARGCNMGNMGNAARGARCARCARCARCARACNAAY GGNAAYTCNAARAARAARMGNAGYAAYAARCCNAARAARTCNACNGARAARGARMGNYTN CARCARYTNGCNTTYGGNTTYTCNMGNCCNGGNTCNACNAAYCCNGARCCNCCNMGNGCN TCNGCNGGNAARGGNGGNAARAAYAARAAYGCNTGGCARCARTGGMGNGAYCAYGAYCAR GARGTNGTNGARGAYCARTTYMGNGARGAYYTNGARAARGCNYTNYTNGARAGYCARGTN CARYTNGARAARAARAARATGGARGAYAARGARAAYAAYGARMGNACNAAYTCNAAYAAY GARGCNCAYGARACNGCNGARGGNGGNAARAARAARAARMGNAARGAYAARTCNAARACN ATGTCNYTNGARGARTTYAAYAAYYTNCARAAYCCNAARYTNCARAARGGN--------- TCNGARGGNTCNCAYAAYGGNGARCCNTCNMGNCCNCCNATHCAYCAYMGNGTNCCNTCN GCNGAYAARGAYTCNAARTTYTTYAAYAGYGCNCARCAYGARGCNAARCARATHATHAAR AARGAYAARATGAARGARGARTAYMGNAARACNGCNGCNGTNGAYAAYGCNGTNGTNGCN AARYTNAARAAYGAYATHGARATHMGNGAYAARACNATHAARGAYYTNAARGARAARATG GARAARTTYGARACNGARATGAARCARGTNAARCAYMGNAAYAARCARYTNTGYGTNATH YTNGCNCARGGNGARATGAARGAYAARGCNCARGTNYTNYTNCARGTNGAYGARYTNAAY AAYGTNAARGAYGARYTNATGGARCARGTNACNTCNYTNACNGCNGARYTNGARAARGAR MGNTCNAARAAYMGNGCNYTNAARCCNGAYGCNGAYAARTCNAARGGNGGNAARCAYGGN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------MGNTAYGARTGYYTNTAYTGYACNGARCAYTAYTCNAAYAGYACN YTNTCNGGNATGAARYTNCAYTAYGCNACNGARCAYCCNGGNCARYTNYTNGTNTTYMGN GAYGTNGARGCNAARAARMGNCARYTNGCNTCNMGNYTNGGNGGNAARGAYAGYTGYTAY AAYATGATGACNTGYATHGCNGARGGNCAYAAYATHGTNGCNYTNGCNAAYYTNMGNCCN GARAAYAARGAYGARYTNGAYAGYTAYATGTAYCARACNGTNGGNCAYCAYGCNATHGAY YTNTAYGCNGARGCNACNGGNYTNCCNYTNTAYACNMGNACNATHCARGGNGAYAGYYTN TCNATHGGNCARGAYTAYCARCCNCAYGARGGNGAYGARGTNGARGAYYTNTTYCARYTN YTNTCNCARATHAARTCNGARATGGARATHGARGCNGTNAGYGTNGGNGCNATHYTNTCN GAYTAYCARMGNGTNMGNGTNGARAAYGTNTGYCARMGNYTNGGNYTNMGNGTNYTNGCN TTYYTNTGGMGNMGNAGYCARMGNGCNYTNYTNMGNGARATGATHGAYAGYGGNYTNAAR GCNATHATHATHAARGTNGCNGCNATGGGNYTNTCNCCNAAYCARCAYYTNGGNATGGAR YTNAARGAYATHTTYCCNCAYATGGTNGARATGAGYGCNAARTAYGGNYTNAAYGARTGY GGNGARGGNGGNGARTAYGARACNTTYGTNTTYGAYTGYCCNATHTTYAARAARTCNATH YTNATHGARGARAARGARYTNGTNATHCAYTCNAAYGAYGCNTTYGCNCCNGTNGGNTAY YTNAAYYTNMGNAARTGYAGYYTNCARGAYAARCCNGGNCAYGAYGTNTCNTCNTTYGTN AAYGAYGTNGAYATHATHCCNATHTCNACNACNACNAARTGGYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TGYGTNCCNTGYTCNAGYGARGAYCARGTNAAR ATHMGNAGYAARAAYAAYTTYTGYTGYACNGAYGTNAARACNCCNGAYGTNGGNGGNGCN CARGCNATGATGACNAGYGCNGCNCAYYTNATGYTNAAYYTNAARCARACNAARGARAAY GAYGCNCARTCNMGN---------YTNGTNTGGATHACNCAYGAYCCNAARAARMGNTCN TTYGTNMGNAGYGAYYTNATHTAYTCNAARGGNCAYATHATHGTNCARTCNGCNGGNGTN TAYCAYYTNTAYAGYCAYATGACNATHGAYTCNACNGGN---GAYTTYCARAGYAARCAY GTNTTYCAYTCNATHTCNAARMGNMGNMGNGARAARCCNGARACNYTNYTNATHACNCAY GTNAGYATHGGNCARGAYGAYYTNAARACNACNAAYYTNGARGGNTCNTTYGARYTNGTN GARGGNGAYGARATHTTYGTNTAYGTNAGYCAYCCNTCNYTNYTNAGYGGNGARYTNACN GCNAAYGTNTTYGGNYTNTTYMGNYTNGARGGNAGYAARATGGCNYTNCARAGYCARGTN GARCARYTNMGNGCNCARYTNGTNMGNGCNGARAAYGAYMGNCARAARATGMGNATHGAY YTNGAYGARTCNMGNATHGARGCNGARGTNAARGARMGNMGNMGNAARMGNAAYGTNGAR GAYGAYMGNAAYMGNGCNYTNGARCAYGAYYTNYTNGARATGAARTCNCAYYTNGTNMGN TCNGTNGGNGCNATGTCNGARATGGARGARGTNAARMGNMGNYTNGARAARAGYGARMGN CARMGNACNCARYTNTCNGAYCAYATHGARACNYTNGTNAARGAYYTNGARAAYMGNGAR MGNCARAGYGCNAARATHATHAAYCARYTNAARGAYACNTCNGAYAARTAYGAYGAYTCN GAYMGNCARMGNGCNYTNYTNTCNACNCARYTNGARGAYATHCAYGGNAARYTNAARGAY GTNACNMGNGARYTNGARAARACNACNCAYGARYTNMGNAAYACNCARYTNYTNYTNGCN GARACNGARAARAARAARGAYGARTTYAARGGNMGNGCNCARGARACNGTNMGNCARTGG AARGCNAARGTNAARCARYTNGARMGNGAYYTNGAYMGNCARAARCAYGGNAAYGGNCAR ATGATGGCNMGNCAYGARCARYTNGTNAARGARATGGARGGNCARAARCARCAYGGNACN TAYAGYCARYTNCARYTNGARGGNYTNAARMGNGARYTNGCNGAYGCNYTNGCNGTNMGN GCNGCNCARGAYGARCARYTNMGNYTNAARGAYATHGARGTNAAYGARYTNAARTCNTTY MGNATGGAYYTNGARMGNGARTAYMGNGAYGGNMGNACNATHACNGARAARYTNGCNGCN CAYYTNYTNGCNCARGAYCARTCNCAYGCNYTNCARGAYGARYTNAARGARYTNAGYMGN GTNAARGCNGAYGTNGCNAGYCARYTNGCNGARACNTCNGCNAARAAYCAYGAYYTNMGN CARGCNGTNGTNGARYTNCARCAYMGNGARAARGCNGCNAARGARGARACNGARATGTAY AARAARCARYTNTAYCARGARMGNAAYGGNYTNAGYAARAAYTAYGARACNYTNAARCAR GARYTNAAYGARGCNAARGTNMGNGARGCNCAYACNYTNCARGARGTNCARMGNAARTTY MGNGCNAAYAAYGCNGARACNGAYGCNACNATHCARGCNYTNAARATGGARYTNTCNGAR GARAARTCNAAYAGYAARATHYTNGGNMGNAAYGCNGAYMGNATGAARGARGARYTNGCN GTNYTNGARAARMGNTTYMGNATGTCNGARGAYGARAAYGCNTCNYTNMGNMGNAARATG GARYTNGTNAARAAYGARTTYGARGCNCARAGYCARYTNGCNGARGAYGAYYTNAAYMGN GTNTGYMGNYTNGARAAYCARYTNAGYGGNGCNCARATGGARYTNGAYAARYTNGARAAR CARCARATHAAYYTNGTNCAYGARATHGCNATHGARATHGAYGCNYTNGTNGARACNGCN TCNACNGAYGCNACNAGYAARTGYCARCCNATHAAYGGNYTNAARAAYYTNGCNACNGTN MGNTCNGGNATHCCNAAYCAYYTNYTNACNGARATHAARAAYAARYTNAARTGGYTNMGN TCNGARTTYMGNGARMGNYTNGTNMGNGARMGNMGNYTNMGNAGYGARTTYMGNACNGCN YTNTCNTCNTCNGARGCNGAYMGNCARTTYYTNATHGGNCARYTNGCNMGNAARGAYGAR GARYTNGAYGAYYTNGCNYTNGARAARCARGARATHGCNTAYAARGARATHCARAAYTCN AGYTTYGTNGARGARYTNGARGARCARGTNYTNGAYYTNTCNGAYGARYTNCARYTNMGN AARATGMGNGARGAYGARCARMGNAARATGTTYGCNMGNGARAARCARAAYATHATHGAR GARATGGARGAYATHATGGAYGCNGARAARGARAARGCNAARATHGARGAYMGNTAYMGN MGNYTNCARGARACNYTNAARTCNYTNCAYCARGAYYTNAARACNACNAAYGTNGARAAR GGNAARAARACNAAYGGNATHYTNMGNTCNCCNTCNCCNAAYGGNACNCCNAARAARMGN AAYCAYGTNMGNATHTCNTCNACNACNCCNACNAARGARTAYGAYGTNGAYGCNCCNACN ------ACNCCNTGYCAYACNCCNCCNCCNATGGCNYTNACNGAYGAYGARTTYMGNTCN AARTTYYTNCCNYTNACNCCNCARGARATH------------------------------ ------------------------------------------------------------ ---------------------GARTAYYTNCCNATHYTNGARTCNGARYTNTCNCARTTY GGNGAYMGNGTNGCNGGNGAYYTNYTNCARYTNTCNATHCARATGGARGAYGARAARCCN MGNYTNGARCARTTYGAYGCNTGGGGNCAYMGNGTNGAYMGNYTNATHACNTCNAGYGCN TGGAARAARATGAARGARGTNTCNGCNGTNGARGGNYTNGTNTCNTCNGGNTAYGARMGN AAYTTYGGNGARTGGAGYMGNYTNTAYCARTTYTCNAARTTYTAYYTNTTYGARCCNTCN GCNGGNYTNTAYACNTGYCCNYTNGCNATGACNAAYGGNGCNGCNMGNACNATHGAR--- ------GARGAYMGNGARATHGAYATHGARAGYGAYGCNGAYGAYGARGAYGGNYTNGGN GCNTTYAGYTCNGTNGAYGAYAARMGNGCNCAYCAYAAYGCNYTNGARMGNAARMGNMGN GAYCAYATHAARGAYAGYTTYCAYAGYYTNMGNGAYTGYGTNCCNCARGAYGAYAAYAAR ------ACNAAYTCNTCNAGYAARACNTCNMGNGCNCARATHYTNMGNCARGCNTCNGAY TAYATHATHMGNATGMGNGAYAARACNTCNCARAAYGAYMGNCAYATHCARATHYTNAAR CARCARAAYGAYGARYTNCARGCNCARATHAARGCNYTNCARAARTCNCARTCNGGNGGN AARGCNYTNATHAAYTCNAGYTTYYTNGAYGAYMGNGGNGAYGAYGAYTAYGARAGYTAY GAYGAYGARCCNGTNGTNGCNTCNCCNCCNAARMGNAARAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GTNGCNAARACNGCNAARTCNYTNGGNGTNATGTCNGAYGCN ATHTAYYTNATHCAYGAYGARYTNGAYYTNGGNYTNGGNAARGTNTCNATHAARAAYMGN GGNAGYGCNAAYGGNCAYMGNGGNGTNYTNTCNTGYATHGCNGAYYTNAARTCN------ ---------------AAYGTN---------------------------------YTNCCN MGNYTNMGNATHGGNATHGGNMGNCCNACNTCNAARTCNCARGTNATHCCNTTYGTNYTN GGNCCNTTYYTNGAYGARGARGTNAARGTNATHCARTCNACNYTNGAYMGNGGNATG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARAARAARGCNGTN ATHAARMGNAGYAARAGYGCNGCNGCNGAYYTNMGNAARCARAARATHGAYGARAAYACN GARAARGARGARGTNTCNGCNGAR------YTNAARGARAARYTNAARAARAGYCAYGGN AARYTNMGNMGNACNGGNTCNGARTAYCARTCNAAYTTYAARGCNCCNTCNGCNTAYTAY AGYMGNAARGGNGTNTGGAARGGNGCNGAYCCNCCNCARYTNATGCCNGTNGCN------ CARGARAARAARGARGARCARGAYGCNAAYGTNAAYAAYAAYGCNGTNGAYGCNGTNCCN YTNTCNAAYTGGTTYGCNGARGTNGTNGARYTNMGNMGNMGNGCNGAYGARTAYMGNAAR MGNGCNCARGGNACNCAYTTYTCNMGNGARCAYYTNGTNCARYTNATGGCNCARCARAAY CARTGYTGGGAYGTNGARTCNTCNTCNTCNTCNACNGTNAARGCNYTNAAYYTNGARGTN CCNAARATHAARMGNAAR------------------------------------------ ---------YTNCARCARGARGARGCNMGNGAYTCNCCNTCNGTNYTNTCNGAYATHGAR ATHGAYGAYYTNGARGARCCNGARGTNGTNGTNGTNAARAARAGYTAYAARTCNGCNTCN CCNGAYGGN---------CARAARATGTCNMGNATGAARAARGAYAARGARGCNGTNTGY CARCARCARMGNAARATGAARGARGCNMGNGCNMGNGAYGTNGAYAAYGGNGAYGAYGAY GARGGNAGYGAYGAYATHGTNAAYGARGARGGNMGNCARCCNACNCCN---AARYTNCAR GCNMGNGCNTCNGTNAAYMGNCAYCAYYTNGAYYTNACNACNCCNGCNGTNGGNGGNGCN YTNYTNACNTGYCCNCCNTCNAARAGYACNAARATGATHGTNACNTCNMGNTCNGGNGAY AGYTAYGTNACNGCNTCNGAYAAYATGGARGTN------GARCARAARAARGTNGAYATG GARAARYTNAARACNMGNCCNATHYTNGGNCARCCNTCNAGYGAYACNCAYGCNYTNMGN GAYGAYGAYGCNTCNTCNGAYMGNGCNYTNAAYACNMGNTAYGTNCCNTCNCCNGCNYTN GCNGGNAGYGAYGAYGAYAARGARAAYGCNCCN---------------TCNAARACNTCN AARYTNAGYMGNYTNACNCCNGCNCARGARGGNGCNGGNAARACNTAY---AARTCNAAR GCNTTYYTNACNYTNGAYGAYATHMGNGCNGAYCARAARGCNGCNGTNGARGAYGAYGTN ATGTCNGTNTCNATGATGTCNGTNGCNTCNAGYTCNTGYYTNGCNTCNGARGTNYTNGAR MGNGCNMGNAARMGNCARAARGARTTYTGGGGNAAR------TTYATGTAYTTYGGNTAY GGNAGYAAYATGYTNGARGARMGNATHCAYATHAARAAYCCNAGYGCNMGNTAYATHGGN AAYGGNYTNYTNAARAARTAYAARTTYGGNTTYGARAARGCNGTNTGYATGGARGARGAY ---GTNGGNGCNGTNGCNACNGTNACNGGNACNGAYACNGAYGARGTNMGNGGNTGYGTN TGGGARATHGAYGARGAYCARGTNAAYAAYYTNGAYMGNCARGARAGYYTNTAYMGNGCN ATHCARGTNGAYGTNGTNYTNGARAAYTGYACNACNGTNTGYTGYMGNACNTAYGARATG AAYTGYGAYGTNMGNCCNAGYGAYACNAARCCNCAYCCNTTYTAYAARMGNATHTGYATH GARGGNGCNAARCARCAYGGNYTNCCNGARGARTAYATHMGNTTYYTNGARAGYTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GAYGCNTTYGGNATGCARGCNTTYAAYCCNAAYCCNGCNCCNTCNGARCAR GARYTNATGGAYATHMGNGAYGGNTTYAGYMGNGGNYTNTCNTTYGGNACNGAYGAYTTY AAYYTNGAYGAYYTNGAYCCNYTNAAYCARMGNYTNATGGGNAARTCNAAYAARAAYMGN AARACNMGNTGYTCNTGYGGNTAYCARGGNTCNAAYAARACNTCNAARYTNTGYTCNAAR TGYCARGGNGCNAARCCNYTNGAYAARGTNYTNTCNACNTCNAGYAGYAARYTNAARGAR CARAARCCNTCNMGNGGNGGNAARATGGAYTCNAARCAYTTYTCNTCNMGNTCNACNACN GAYAAYYTNCCNAGYTCNYTNAGYACNCCNGGNGARMGNGCNGGNYTNAGYTCNACNTCN CCNTCNGCNGTNGAYACNTCNGTNGCNACNTCNTCNACNAGYTCN---AAYACNATGTCN CCNCAYYTNTCNACNTCNTGYGGNACNTCNGGNCCNACNGCNGAYATHACNTCNCAYTCN ACNTCNAAYTCNACNAAYGCNACNGARGCNGARGTNGARACNGCNAAYGAYTCNGARTCN TCNCAYTCNTGYGCNAGYGAYAARACNTAYGAYCCNAARAGYGAYTCNTCNAAYTCNTGY TCNAGYYTNGCNAGYTCNYTNTCNGCNGTNATHTCNTCNAAYTCNGAYTTYCARGGNACN GGNYTNTCNAGYAGYACNACNGAYGGNCCNAGYYTNTCNCCNAAYGCNAARAAYTCNGTN ACNTCNTCNAAYAAYACNGTNAGYAAYGGNCARAAYAAYMGNGTNGAYACNACNACNTCN AAYGCNGGNAAYACNATHACNTCNTCNAAYTCNAAYAARGAYAAYGCNTCNGCNATHGAR MGNAGYGARGAYCARAGYAARGAYTCNTCNACNCARACNACNAARTCNTCNCAYCCNGCN ACNGGNYTNCCNTCNGGNTCNAGYYTNYTNAARGAYCCNAARCCNTCN------------ ------------ATHGARGAYGCNTCNCARCCNTCNCCNTCNGCNMGNGGNGTNAARMGN CCNCAYGARGARGTNGARGAYATHAAYGARAGYCCNAAYTCNCCNAARCCNTCNCCNCAR AARAAYAARAARMGNTGYTTYACNTGYGGNTGYMGNYTNGARYTNGCNCARMGNACNATH GGNAARTGYMGNTGYGAYCAYGTNTTYTGYCCNATGCAYMGNYTNCCNGARYTNCAYGGN TGYGARTTYAAYCAYAARGARGAYGGNMGNMGNGARGCNMGNGARAARATGGTNAARCCN ACNMGNCAYATGGGNACNTCNTTYMGNMGNGAYYTNTGYGAYCARGARAARGAYGAYATH YTNAAYGAYGCNTAYYTNAARGARGTNMGNTAYGGNMGNGGNGGNTAYGTNGTNAAYGGN GTNCCNATHGCNMGNAAYATHGARGGNTGYTGYAAYAARGAYCCNTGYTTYTGYMGNTCN GAYGTNATHTTYTAYGAYGGNGTNGCNTAYGAYCARAARCCNTTYATHGARGGNAAYATG MGNACNMGNGARGGNGAYGTNATGTAYTTYGARGGNAARATGGTNGGNCCNTTYAAYCCN GGNAARTCNCCNYTNAARTTYGGNCCNAAYAARACNMGNGARACNCAYCCNACNGARAAY TGYTTYAAYTCNAGYGTNCAYAGYTAYGCNMGNCAYCCNTGYTGYMGNACNTCNATHTAY GGN---------CCNGGNAAYGCNGAYGCNAAYAARYTNGCNTAYACNMGNATGGGNYTN CCNCAYGGNAAYACNATHGGNTAYTTYMGNTTYAARCCNGARMGNATHTGYTAYGAYMGN GAYCCNCCNGTNGCNMGNYTNGARGAYTGYTGYGAYTGYMGNCCNTTYGARTAYGAYGCN AGYCARTAYATHCARGAYGARTGYCCNGGNAARACNTGYTGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGTCNGTNATHACNTGYYTNACNTGYAAYGTNGGNTTYGARGAY GTNGAYYTNGGNMGNATHCAYTAYAARACNGAYTGGCAYMGNTAYAAYYTNAARMGNAAR GTNGCNAGYYTNCCNCCNGTNACNYTNGAYAARTTYGARGARMGN---------CARAAR GCNCARGARCAR---YTNGAYGCNACNACNCARGARMGNTGYGCNTGYGARCCNTGYAAY AARTGGTTYAAYACNACNAAYGCNTAYCARAAYCAYYTNCARTCNAARAARCAYMGNGAY GTNATHTCNGGNTCNGGNAARYTNAARAARGGNAARAARAARAARTCNGGNGCNCAYATH GCNACNATGGTNGARCARATHCCNAARGARAARGAYGAYGARGAYGARGAYATGTCNGAR GCNGARGAYGAYTCNGAYGCNGARTCNTGGGAYAGYTAYGAYGARAARATHATHGCNYTN GARGARTGYYTNTTYTGYTCNYTNGTNAGYCCNTCNATGGARGAYAGYYTNACNCAYATG ACNTCNTGYCAYGGNTTYTTYYTNCCNGAYGCNGARTAYATHTGYGAYYTNGARGGNYTN ATGTCNTAYYTNGGNGARAARGTNGGNGCNGGNTGYGTNTGYYTNTGGTGYAAYGARAAR GGNAARMGNTTYMGNTCNTCNAARGAYGTNCARAARCAYATGGTNGAYATGGGNCAYTGY AARATHTTYCAYGARCARGARACNYTNTTYGARTTYACNGAYTTYTAYGAYTAYTCNAAR AGYTAYCCN------TCNGCNGARGAY------GARGAYCCNAAY---TGYGCNGTNGAY GTNATGGARYTNGAYGGNGAYGGNTAYTCNYTNACNYTNCCNTCNGGNACNGTNATHGGN CAYMGNACNYTNYTNMGNTAYTAYMGNCARAAYYTNGCNCCNTAYAARAAYGARAARAAY AARACNGTNYTNCCNAARATGYTNGCNCAYTAYAARGCNYTNGGNTGGACNGGNGCNACN GGNCCNYTNGTNGARMGNMGNGCNAARGAYYTNCARTAYATGCARMGNGTNMGNAAYMGN CAYTTYATGAARYTNGGNACNAARGGNAAYMGNYTNMGNYTNMGNYTNMGNYTNCARAAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MGN GARYTNYTNCCNCARATHCAYCARGTNTGGTCNGGNTTYTAYCCNMGNTTYCAYAGYGAR GARAARTTYGTNGTNATHAARGCNGTNCARACNYTNAARGTNATGGCNGAYGCNAGYGGN AGYTTYATHGTNCARMGNGTNATGAARGAYGTNGTNCCNGGNYTNTCNCARTTYATGGAR AARCARGGNAGYATHAGYTGYGARAGYMGNTCNACNTAYGTNAAYACNGCNAGYTTYAAR YTNCARGTNGCNATHYTNGARTCNYTNGGNCCNYTNGCNGARAARATGGARYTNAARGAR MGNAAYYTNGAYGTNGTNGCNAARATHTGYYTNCCNTAYYTNAGYTGYYTNCARCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CAYGGNTCNCAYTCNGGN TCNCARGGNCARGARTCNATGACNYTNCCNAARTTYAARCAYAARTAYYTNTCNCAYACN CARYTNGCNCCNMGNMGNCCNATHGGNACNTTYAARTTYTTYYTNYTNGGNMGNACNGAR MGNCARACNGTNTTYAAYAARGGNACNCARACNAARGAYGARCCNYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNMGNMGNGGNMGNGTNMGNAARAARTCNGCNAARGTN YTNGARATGGARGARTTYGARCARGCNGARAARGTNACNGTNCCNAARAARTCNAARACN TCNAARACNTCNGAYACNGCNGTNCCNGTNAARAARGGNAARGGNACNATHGARGGNACN CCNACNTCNMGNAARAGYAARAARGTNGCNGCNAGYAARAGYMGNTCNGTNCCNGCNGAR YTNACNCCNMGNACNATHAAYGCNCCNATHCARGTNCARCARCARGARATHAARGARGAY CCNAARAGYGTNATHAARTAYYTNYTNACNTCNCCNGTNGCNGGNACNCARCAYTCNCCN GCNGCNGTNATHGCNACNAAYATGGARCCNCAR---TCNGCNTCNACNCCN------GTN GTNCCNGTNAARAARTCNAGYAARAAR------------ATHAARTTYGARGAYGGNACN AGYGCNCCNAARAARAARGARAARAARATGAARATHGARATHATGTCNCCNTCNGARGTN TCNTCNGCNCCNCCNYTNCCNCCNCCNYTNGAYCARAARGCNCCNAGYYTNAARATGAAR ATHATGTCNGGNTCNAAYCCNATGACNGCNCARGTNGCNATGGARACN---CARGGNAAY AGYGCNAGYCCNGCNCCNAARGTNAARAARTCNAGYAARAARGCNAARCARGAYACNGGN GTNAARCARGARTTYGCNAGY------------------------------------CCN GARGAYGGNGARAARGCNCCNAARAARAAR------------AARAARAARGARAARYTN ATHCARAAYGCNATHAGYGCNGCNCARCARATGCCNAAYYTNGCNGCNYTNGTNACNACN ---------CCNCARAGYCARGTNATGGGNGGNYTNGGNCARTCNCCNTCNCCNACNACN TCNAARCCNAARAARAARGCNAARAGYTCNGCNCCNTCNATHAARACNGARAAYACNAGY GAYTCNYTNGTN---------ATGGAYTTYGAYGARAAYATGGARGAYGARGARTCNACN YTNGTNATHGCNGARACNGARAARAARAARAARAARAGYTCNACNAARAARAARAGYCCN AARGARAARGGNGAYCARTCNAGYCCNAARGCNGARAAR---GCNAARAARATHCCNAAR MGNGCNCCNACNGCNTAYATGYTNTTYTGYAAYTCNCAYMGNCCNGCNATHGTNGCNGAR AAYCCNGGNATHGARTTYGCNGGNATHAGYMGNAARYTNGGNGARYTNTGGCARACNCAR TCNAAYAARCARAARYTNCARTGGMGNMGNAARGCNCARMGNMGNATGAARAARTCNAAY YTNATHTCNACNGGNAARGTNGGNGGNAARGARGTNCARGGNGGNGCNGTNGGNCCNYTN AGY---------------------TCNACNAAYAARAARYTNGCNYTNATGYTNCARAAR AGYAARCCNGTNGTNGTNGARGARGGNCCNYTNAGYCCNACNAARAAYTTYAGYATHGAR CCNYTNGAYGTNGCNGCNCAYYTNAARYTNYTNGGNGARTCNYTNAGYATHATHGGNATG MGNYTNCARGARCAYAARGGNATGATHGCNGTNCARGGNAGYYTNTCNGTNYTNYTNGAY TCNTTYYTNTGYGCNTGYGGNCCNYTNYTNTGYYTNACNCARCARGTNCCNGGNATGGAY GGNTGYTCNCCNYTNGTNCAYGCNCARACNYTNGAYAGYGTNGCNTAYGTNATGCCNGGN YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AAYAARATGAGYAGYGTNCAYCCNAAYCCNCCNCCNCCNCCNTAY--- ACNACNGGNGGNGCNGAYCCNCCNCCNCCNCCNGCNGGNTAYTAYGGNGCNCCNCCNCCN CARGCNTAYGGNGCNCCNGCN---------------CCNGCNGGNTAYGGNCCNCCNCCN CCN---GGNTAYGGNGCNCCNCCNCCN---GGNTAYGGNCCNGGNCCN------------ ------------------------------TCNTAYCCNCARCARCARTAYCAYCCNCAR ------------GGNCAYTAYCARCARCARCCN---CARCARGTNGTNTAYATHMGNGAR GARMGNAAR---AARGAYAARGAYAAYTCNGCNGARACNTGYTGYATHATHGCNYTNTGY AGYGCNYTNGTNTGYTGYTGYYTNATG---ATGGCNGAYAGYAAYYTNCCNMGNCARGAY TTYGCNCCNCCNTGGYTNAARTTYCCNTCNGAYTCNACNAARTCNACNAAYCARAARACN AAYTCNTAYCARGGNGAYMGNAAYMGNCCNMGNMGNGARGAYCCNTAYTAYTCNMGNTCN GAYTTYAAYMGNYTNCAYMGNCARAAYTCNYTNGAYTTYCAYGARGGNAARMGNTAYCCN TCNGGNCCNAAYAARTAYMGNCAYCAYTCNGTNGAYGAYGAYTAYGGNGGNTAYTCNTAY GGNTAYGGNTAYTAYCCNTCNAGYTAYAAYTAYGARAARTAYGGNATGCAYTTYAGYTCN CARCCNACNYTNGCNMGNACNGGNAGYMGNGAYGGNAARTAYCCNGCNGGNMGNGTNAAY CARATGAAYGGNAAYGCNYTNYTNAAYGGNCCNCAYGAYYTNTTYGARCCNTAYTAYCAR CARGGNTCNMGNAARGCNCAYCARGAYMGNGAYTCNATHMGNGARGTNMGNAAYGGNGAY GTNAARGAYAARGARAARGCNACNGARAARGAYMGNCCNTTYAAYGAYGAYTTYCCNTCN YTNAAYGGNTCNGGNGARTCNTCNGTNGAYTCNAARGCNAARCCNGCNTCNGGNGTNTGG GARAAYCCNCCNAARTCNTCN---AGYAARAAYGARGARTCNACNGAYYTNYTNAARAAY ACNTCNCCNGGNATHTAYAARGCNYTNGTNCCNAGYAARAGYGTNCARCCNAARAARCCN GTNAARGAYGTNCARMGNGTNAAYGGNAGYGTNMGNGARATHTCNCCNYTNAGYCCNTCN AAYAARCCNGGNCAYMGNGARGGNTCNMGNTAYAGYCCNACNCCNGAYYTNGCNATHGTN ACNCARCCNAARAARYTNGGNGAYAARAARAGYGAYTTYYTNMGNGCNATHMGNAAYGAR AGYTCNATHMGNAAYGGNGARGTNTGYCARAAYCARAAYCARAARGTNGAYMGNAARYTN GARTCNAARCARGAYACNAAYGAYAAY------------GAYGTNAAYGGNTAYACNCAY YTNAAYGGNGAYMGNCAYGTNGAY---------------ACNAAYGARGARAARATGGGN YTNAAYGGNGAYATGAARGAYGARTGYGTNAAYGGNGAY---------GCNYTNATHAAY CAYGTNGAYCAYATHTCNYTNTCNGGNGARGARGARGARMGNMGNYTNYTNYTNTCNATG GGNTGGGTNGARGARGAYAAYACNGARTAYGARATHACNGARGAYGARATHMGNGARTTY AARAAYYTNNNNCARACNCAYTGYCAYACNCARAARAAYGGNYTN---------YTNMGN AGYGCNYTNGAYMGNAARYTNGGN------AAYGAYGGNATGYTNAAYGGNATHTCNACN CARGAYGARAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYGGNMGNTAYCCNMGNGARTAYAAYCCNAARGTNCAYGGN CCNTAYATGCCNGGNMGNTTYTAYGGNAARCCNGAYACNCCNTTYGGNCARGTNAARATH GGNGARATGGGNGCNTGGYTNGCNMGNMGNAAYAARACNCCNGARGGNATHTGGTCNGCN ATHCAYMGNTCNTAYTGGMGNTGGGCNCARGCNAAYYTNCAYGTNMGNCARAGYGGNTTY GTNCCNYTNGGNCARGCNGCNATGYTNYTNTCNATHACNTTYTTYGCNYTNYTNTAYAAR GARMGNAGYYTNCARCARGARYTNGCNGAYGCNAARGARGARMGNGARGCNACNCARGAR GARYTNGCNGARAGYMGNMGNAAYGCNGCNGARYTNAARGCNACNATHTCNAAYYTNGGN GAYGAYYTNAAYAARTAYMGNAAYYTNCARGARGARAGYACNGCNGAYATHMGNYTNAAR AAYGARCAYYTNAARGARCARGARGTNGCNYTNTCNGARACNMGNCARCARYTNGTNATH GCNGARAGYCARYTNGARGTNGCNACNGARAARACNGARCARYTNGARACNGCNCARGCN GCNYTNAARCARAARTAYAGYCARGCNGTNACNCARATHGGNCAYYTNGARACNACNGTN AAYGCNYTNCARGAYAARYTNGCNGARAGYMGNAGYMGNGARATHGAYAARGARCARGCN GTNGARCARYTNMGNGCNGARYTNGARGGNYTNGAYMGNGCNTAYTCNGAYAGYAARGAR GARYTNACNAARTGYGARGAYATGATHCAYCARYTNACNACNGARYTNGAYTCNTCNCAR AARGARATHGGNTCNTCNCAYAARMGNATHAARGAYYTNGARGAYACNGGNMGNGARATH MGNGARCARYTNCARAAYGCNCARCAYCARGCNYTNCARAAYGAYGARMGNGCNCAYAAY YTNGARAAYAARYTNYTNTCNTAYCARGGNGARCAYAGYCAYTCNGAYMGNGARTTYYTN GARAARGARGARCARATHAAYGGNYTNGARTAYCARYTNGARGARACNAARAGYGAYGTN GARATGMGNCARTCNACNGTNGAYCARYTNAARGCNGAYYTNGCNATHACNCARTCNGAY YTNTCNCARGCNMGNGARGAYAARAGYGCNGCNYTNAARGARATHGAYMGNYTNGARCAR CARAGYCARCARYTNCARYTNAAYYTNGCNTCNGCNCAYCARMGNCAYAARAGYGARACN TGYMGNYTNGARGARCARGTNTCNTCNYTNGARMGNCARGGNTCNGAYACNCARGCNGCN YTNMGNAGYGCNGARTGYGARGTNAAYAAYAARGARGARCARATHAARMGNAAYGARGCN GARATHGCNTCNTGYMGNGAYGAYATHMGNAGYAARGTNGAYGARATGGARMGNYTNGAR MGNTCNYTNCAYGARGCNMGNYTNGAYATGAAYCARACNTCNGTNCARTGYAARCARYTN GARAAYGTNATHGCNGARYTNAARTCNGAYGGNGARAAYYTNMGNAARGAYYTNAAYGAR GCNMGNYTNCARTAYAARGAYTGYGCNCARGARYTNGCNCAYCAYGARGARAARYTNAGY YTNATGGARCAYAGYYTNCARTCNACNCARGAYCARYTNAGYCARMGNGTNACNGARATH GTNMGNCAYGARCARAAYACNMGNAARYTNCARGCNGARYTNAARGCNATHAARGARMGN GCNGARGCNTAYGARGARGARATGGARGARCARAARGGNATGATHGAYAARYTNMGNAAR GAYYTNGTNGCNTCNAARGARGARTAYCAYGCNTCNGTNCARGARGGNATHGCNTAYAAR CARCARGCNCAYAARAAYCARYTNGARYTNAAYGGNAGYMGNGARCARGARAARATGYTN TCNGAYCARGTNGARCARCARGARCARATHYTNAAYCARYTNCARACNGARYTNMGNGCN GARMGNGARMGNCAYGGNGAYACNGTNCARCARYTNAGYGCNAGYAARAARAAYGGNYTN GAYYTNCARGCNGAYYTNGARGCNATGCARAARCARGTNMGNGARYTNCARGAYMGNGTN AARGCNMGNGARGARCARATGGTNMGNYTNMGNCAYGARATHGAYACNCARCAYCARMGN AGYMGNGARAGYAAYGARYTNATGGCNGARAARGAYGGNCARYTNMGNYTNGCNGARATG AAYYTNCARACNGCNCARAARCARGCNAARCAYCAYGCNCARGARATHGCNMGNTAYGAR GAYACNYTNGCNCARATGCARACNGAYATGGARAARYTNCARGARCARTAYMGNCARGCN TCNTCNAAYYTNATGGARGCNGAYAGYAARGTNCAYGARYTNAARGTNCARYTNACNACN YTNCARGGNCAYCAYAARGARGCNATGGAYCARYTNACNGAYAARGCNMGNCARYTNGCN GGNATHAARACNGARGCNGCNAARATGGCNCARCARAAYAAYTCNATGAARGAYGARATH ATGACNTAYGAYGARAARGTNMGNMGNYTNTCNCARGARYTNMGNAARAGYCARGARATH AAYAARGCNACNGARGAYGARYTNCARCAYTTYGARGARMGNTAYACNAGYYTNCARGTN GAYYTNGTNTCNAGYCARGARAARCARAARCAYTCNYTNCARGARYTNTCNTCNAARGAR GARGARAAYGTNGTNGTNAARGTNGARYTNAGYTCNYTNCARGARAARTAYAARGCNGTN AAYGAYGARGTNCAYAARYTNACNAGYGARYTNGARYTNACNAARCARAAYTAYMGNAGY GCNACNGARGARATHTCNGGNYTNMGNGTNGCNYTNGARGARTCNMGNGCNAAYGGNGAY MGNYTNCAYMGNGARAGYGARYTNGTNGTNCAYAAYGTNAAYACNTGGGTNCARGARCAR AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MGNMGNGTNACNGTNCARGGNYTNTCNAAYCAYCAYCARGCN------TCNCCN GGNYTNTAYGAYGAYAGYYTNTCNGARTTYAGYGAYAAYAAYMGNAGYGARGTNTCNGAR AAYYTNGTNTCNGCNTAYAARAAYATGACNAARGARGARYTNYTNMGNGTNGCNATHCAR ACNAARGCNCARATGATHMGNAARGARAARTAYATHAARGAYYTNGARAAYTAYATHGAY GAYYTNYTNGTNMGNGTNATGGARACNACNCCNMGNYTNYTNACNMGNGTNYTNYTNATH AGYAARATGTGYATHCARYTNAARATHAARYTNACNACNGTNTTYAARAARACNMGNGAR GGNYTNCCNCARGTNATHTGYCARGTNTAYGTNTCNGARMGNYTNYTNGCNACNGARTCN ATGCCNAGYMGNMGNGAYGCNCARGAYAAYGCNTTYMGNGCNGTNMGNATGACNYTNATG GCNGCNMGNGGNAGYGAYGTNATHAAYAAYTTYCCNCCNYTNGAYCCNCARGAYYTNAAR GGNGARGAYGTNYTNGAYGTNGTNCAYAARGGNTAYGCNAARATHACNGARTCNAAYMGN GCNAARATGYTNMGNTCNMGNGGNGCNAAYGTNGTNYTNGCNATGMGNYTNGAYYTNGCN CARTAYGTNGAYATHYTNAARACNCARCCNAAYCARTCNCARGGNMGNTAYMGNYTNYTN CCNGAYTCNGARMGNCCNTCNTTYAAYGAYGTNGCNGGNGARATHGCNGTNAAYGAYTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARMGNATHGCNYTNYTN CARMGNGARAARGARGTNATHTAYMGNAARATHCARGARATHCAYCAYCARCARGARGCN GAYMGNCARAARGAYCARTTYCARTCNCAYMGNAGYYTNCAYAGYCARMGNAARGAYGAR YTNYTNGAYACNYTNMGNGTNYTNAARGARAARYTNGARGARCARAGYMGN--------- ATGGCNTCNACNTCNCCNAARCCNAARAARGGNATHYTNAARAGYACNAAYAGYATHGAY CAYGGNAARAARGARYTNGARTGGGAYGARATGAAYATHYTNGCNACNCAYCAYCCNCCN GAYAARGAYTAYGGNTTYATGAARGTNGAYGARCCNCCNACNCCNTAYAGYMGNGCNGCN ATHTCNGAYAAYGARGARGARGARTCNAGYGTNCARMGNAARGGNAGYGTNGARMGNGAY YTNGGNYTNGAYCCNGGNGAYYTNGCNTCNMGNYTNACNGGNCAYGAYGAY--------- GAYAARCAYTTYGTNGAYGAYGAYGARGAYTCNGAYGARGAYGAYTCNGARYTNACNGAR GARGARAARGCNCAYMGNAARGCNTTYATGATGAARMGNAARYTNCAYTAYAAYGARTTY CARGCNGTNCARYTNGCNAARAARYTNATGGCNGARGAYAARGAYGAYGAYGAYGAYGAY GARGAY---------------------GAYATGMGNATHAAYCARTTYGAYATHGGNGAR ACNATHGCNCARMGNMGNMGNMGNGCNGGNGTNTTYAARAAYCARTCNGGNCCNCCNCCN GARMGNMGNAGYACNATHAGYAGY---ATG---ACNAGYAGYTAYCARGTNACNMGNATG MGNAAYYTNTCNGGNGGNAGYAGYGGNAGYGCNGCNAGYGGNAGYAGYAGYGGNAGYTCN GTNCARYTNGAYAAYCARTAYTCNTCNACNGAYAAYAAYYTNTAYTTY---AAYTGYTAY ATHCCNCCNTTYTCNAAYACNTCNGCNGCNCAYAARCAYAAYGARGAYTCNGTNTCNACN ACNTCNCAYMGNAARYTNGAYMGNAGYYTNAGYGAYAGYGAYAGYGAYMGN--------- ---------------------------TCNGGNAGYMGNTAYAARACNGARYTNTGYMGN CCNTTYGARGARAGYGGNTCNTGYAARTAYGGNGAYAARTGYCARTTYGCNCAYGGNGCN CAYGARYTNMGNAAYYTNGCNMGNCAYCCNAARTAYAARACNGARYTNTGYMGNACNTTY CAYACNATHGGNTTYTGYCCNTAYGGNCCNMGNTGYCAYTTYATHCAYGARGAYGAY--- ------AARGGNGARGCNCARCCNAARATGGGN--------------------------- ---AGYAGYGGNAGYGGNAAYAAYAGYCCNTCNYTNAGYCCNACNYTNCAYGARCARAAY ------AAYTTYTCNTAYTCNTCNGARTCNTCNMGNGTNAAYATHGARAAYACNCARATH AAYAAY---------TCNYTNACNGTNAAYATHAAY---TAYGGN---------AAYGCN GAYYTNCARTCNYTNAAY---CAR---TTYAAYTCNGCNYTNAAYYTNAAYMGNAAYTGY AAYGARTCNTCNTCNTAYAAYAAR------------------------------------ ------------TCNGARGARTAYGAYATHTTYAGYTCNATHTCNGTNTTYAAYCCNGAR GARGTN---GTNGAYAAYGCNCCNCCNAARCCNTCNTCNTTYTCNACNACNTCNTCNCAY TGYAAYCARAAYYTNGAYAAYTAY---CCN---GGNTAYACNTCNTGYTAYTGGCCNTCN ------AAYYTNTCNTCNCARAGYATHGCNCCNGTNGAYCCNTTYAAYTAYTCNCCNACN GGNTCNACNGGNTCNTCNAGYTCNTCNTCNAGYTCNGAYTCNAGYAGYGGNAGYGAYTGY AGYGGNAGYACNGARAGYYTNGTNAGYTCNGGN---------AARMGNACNGCNTGGTGG AAYGARGTNGTNAARAGYAARGTNAARGARAARAARATHGCNTGGAARAARTAYYTNGCN AAYAARACNGARGAYGAYTAYGAYTCNTAYAARACNAARMGNAAYGCNGCNAARGARATH GTNMGNAARTCNAARCARAAYGARTGGGARAARTTYGGNGARAARYTNGARAAYGTNTTY AARGAYAAYCARAARYTNTTYTGGGGNGCNATGAARMGNTGYMGNMGNGGNAAYTCNAGY ACNGCNMGNCAYATHAARAAYGCNAAYGGNGARATHGTNAARAAYGARGARAARATHYTN GARACNTGGAARGARCAYTTY---------------------------------ATGTTY MGNAAYTTYTCNTCNGCNGCNTGYGCNYTNGCNGTNGGNGTNAARAARGARYTNYTNGAY TGYGGNGARACNGCNCARGCNTCNGCNAAYAARTTYTGYYTNGARAARTGYYTNCCNAAR YTNGAYAARGAYTGYTGYAAYACNTAYGTNGGNGAYMGNATHAARAARGCNGTNGGNTTY CCNCARYTNACNGCNTGYTGYAARCCNYTNMGNTAYAARGAYTTYATHATHTCNTAYGAY ACNAARAAYMGNATHCCNAAYTGGGTNTAYGARCAYYTNTAYTTYAGYAARYTNTTYAAR GAYGAYATHTGYGAYAARMGN---------------------CCNAAYGAYAARCCNAAR TTYCAYCCNGAYTGYMGNATHCAYGGNTAYCAYMGNGCNGAYGTNAARGAYTAYTGYGAY TCNGAYTAYGARYTNGGNYTNATGGCNGAYCCNGCNAAYTAYCCNTAYGAYTGYGARGCN GCNGCNGARACNCARGTNATGACNAAYGTNGTNCCNATHGTNCCNGGNTTYAGYTGYGGN CCNTGGTTYGARYTNCARTGYTAYATHMGNGAYACNYTNGTNAARGARCAYAARAGYGTN TAYGTNTGYTCNGGNCCNYTNTTYATGCCNAAYGCNCARCARCCNACNAARAAYATGAAR TTYGAYGTNYTNGGNGARGGNGARGTNTCNGTNCCNACNCAYTTYTTYAARGTNATHATH ATHGARACNYTNGAYGGNAAYYTNGARYTNGARTCNTAYATGATGCCNAAY--------- AARGARGTNGAYGARACNGAYYTNGAYAARTTYYTNACNCCNYTNTGYAARATHGARCAY TAYTCNGGNYTNATHTTYTTYCCNGARAARAARGTNTGYTTYACNAGYAAYAAYAARMGN MGNGGNGCNGCNYTNCAYGCNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNYTNGARGGNTAYCARAARGTNAAYGCNMGNTTYGCNTGYGAR MGNTGYGGNGGNTAYMGNTTYATHCCNTGYGARTTYTGYCAYGGNAGYAARMGNTCNYTN ATHMGNAAYCAYTTYACNGARGAYTTYTTYGCNYTNMGNTGYATGCAYTGYGAYGAYAAY GGNYTNMGNMGNTGYGAYYTNTGYAARGARCARCARGARYTNAGYYTNTAYTGYAARAAY GTNYTNYTNAAYCARGTNATHGAYATHAAYTCNAARYTNGAYYTNTCNTCNAAYAARYTN GCNMGNGTNTAYGGNATHGGNTGYGTNCAYATHYTNCARGTNAGYACNAARAAYAAYYTN YTNTCNGGNGTNATHGGNGARCCNACNAARATHCAYATHTCNTCNGTNCAYAGYTCNGAR TTYCAYMGNYTNTGGCAYGAYATG---GARAAYYTNCCNGARYTNGGNGGNYTNGAYACN GARTAYAAYAARGTNGARMGNYTNTTYTCNATHAAYAAR---TCNTCNTCNAARTTYTTY MGNCCNCAYGGNATHATHYTNCAYGGNCCNCCNGGNTGYGGNAARACNTCNTTYGGNMGN AGYGTNGCNAARMGNTGYGGNGCNGTNTTYTAYAAYGTNGARCCNTCNAAYYTNYTNACN TCNGAYTTYGGNAGYGGNGCNACNGCNYTNAAYGAYATHTTYTCNMGNGTNYTNTCNYTN YTNGARGARGGNTCNGTNGTNYTNTTYYTNGAYGARYTNGAYGTNYTNTGYCCNMGNCCN GARATGGCNAGYYTNGGNAAYMGNCARYTNTGYAAYGCNATGATGTCNGARATGGAYMGN GTNCAYTGYAARAAYGTNTCNGGNYTNYTNATHATHGCNACNACNAAYTCNGTNGCNAGY ATHGAYCCNGGNYTNMGNMGNCCNGGNMGNTTYGAYCARGARATHYTNATHAAYGTNCCN TCNGARYTNCARMGNYTNGCNATHYTNAAYGTNYTNACNACNGGNATGGCNYTNGCNTCN GAYGTNTCNTGYGARGCNYTNGCNMGNATHACNCCNGGNTTYGTNGGNGCNGAYYTNMGN GGNYTNTGYGARGARGCNATHGAYCAYGCNCARAAYGARACNATGCARAARCCNACN--- ---ACNYTNAGYATGGCNGAYTTYGAYCAYGCNYTNCAYAARACNGTNCCNTCNYTNAAR AARGGNAGYGARTGYGTNGTNGAYATHCAYCCNGTNMGNTGGAGYGAYATHGGNAGYYTN GAYGAYATHAARGCNCARATHAARCARTCNATHGARTGGCCNYTNGCNTAYCCNGAYGTN YTNCARMGNATGGAYATHTCNCCNGCNAARGGNATHYTNYTNTAYGGNCCNCCNGGNTGY TGYAARACNACNYTNGTNMGNGCNGCNGCNACNGCNTGYAAYGTNTCNTTYYTNTCNYTN AGYGGNGCNCARGTNTAYTCNGCNTAYGTNGGNGARTCNGARMGNYTNGTNTCNCARGCN TTYCARAARGCNMGNGCNYTNGCNCCNTCNATHYTNTTYTTYGAYGARATHGARTCNYTN GTNGGNAARMGNGTNGCNACNGTNGGNTAYAAYMGNGTNCARGARMGNATHYTNTCNACN ATGYTNAAYGARATGGAYGGNGTNGGNAAYMGNYTNGAYATGAARCARGAYGCNCCNTCN AAY---------CCNGCNAGYCAYGCNGGNACNTGGATGCARAARACNATGGARMGNGTN GTNGARAAYGGNGAYAAYTGYTCNTCNGGNACNACNAARGGNAGYGTNGGNGGNGAYGGN GCNAAYYTNMGNGTNATHGTNGTNGGNGCNACNAAYMGNCCNGAYATGYTNGAYCCNGCN ATHYTNMGNCCNGGNMGNYTNGAYAARCAYATHTAYGTNCCNCCNCCNGAYYTNCARGCN MGNMGNTCNATHYTNGARATHTAYACNTCNMGNATGTCNTGYGTNGGNGTNGAYYTNTCN CARYTNGCNGGNGARACNGAYATGTAYAGYGGNGCNGAYYTNAARAAYYTNTGYAARGAR GCNGGNYTNCARGCNYTNMGNGCNCARYTNTCNTCNGAYGAYCCNTCNAGYAGYYTNGTN GTNACNCARGAYCAYTTYGTNCARGCNYTNGCNCAYGTNAARCCNTCNYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARGGNAARGGNYTNTCNGGNGCNGTNAARGARTGGAARGCNAARTTYYTNCCNATH TAYATGATHGAYTGGGCNTTYTGGCCNGCNGCNCARYTNATHAAYTTYMGNTTYYTNCCN ACNMGNTTYMGNGTNYTNTAYGTNAGYTTYGCNACNYTNYTNTGGAAYTCNTTYYTNTCN TTYATGAARCAYMGNCAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARAGYCAYGARCARACNGTNGAYGAY YTNAARMGNAARCARATGAAYAAYMGNMGNAAYCARGARGCNAARYTNAARGAYGAYYTN GCNMGNMGNAARMGNGARTGGGARCARAARAARGARGARGARAARAARGARCARCARGAR YTNMGNGARCAYGAR---GCNGARATHNNNAARYTNYTNAGYAGYCARGTNTCNATHTCN GARACNGARAARGAYMGNATHATGAARGARCAYGARAARCARATGGTNAARYTNGARAAY AGYYTNACNYTNTCNAARYTNAARCARMGNMGNATGYTNGARGARAARATHGCNCARAAR MGNGCNMGNCARATGGARGARYTNGARAARAARCARAAYGCNGARGTNGARAARCARMGN MGNATHGCNGARAAYAAYGGNGARGARGARGAYGAYGTNCARMGNAARGTNGAR------ ACNATGAARAARCAYGTNCARCARAARATHGCNYTNGCNCARGGNCARCARYTNGAYATG GARGARGARYTNGAYGARATHMGNCAYGARATGACNAARGAYMGNGCNYTNGCNYTNAAR GAYCARGARGARMGNYTNGGNGCNYTNATHGCNTCNYTNCARATGGAYAARGCNMGNGAR YTNGCNAARATHGARGARCARCARAARGCNATHAAYAAYYTNAARTCNAAYYTNATGGAY GAYYTNAAYGCNAARGGNGTNYTNTCNACNCCNGARTGYCARAARATHYTNAAYGTNCAY AARGARGARCARGAYAAYATHAAYMGNAARYTNGAYGGNCARMGNGCNAARCARGARAAR GCNYTNMGNGCNAARYTNCARCARMGNATGGARCARMGNGARCARTCNATHYTNTTYMGN CARGAYGARGARATGCARACNYTNATHAAYAARGTNACNAAYAARAARCARAARATHGCN CARGARCARGARYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNAAYGCNCARYTNGAYAARYTNGCNAGYYTNGTNGAYAARYTNGARTGY AARATHAARTTYGARAAYTTYMGNGAYGARGARGTNGTNACNACNAAYAAYGAYACNGTN YTNYTNGTNCARMGNGARTTYGTNGTNAARGARGAYGCNACNGCNGARTTYMGNTCNCAR YTNMGNGCNTAYGTNGAYGTNACNCARGGNTTYMGNGGNTGYTTY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GCN CARATHATHGAYATHTAYCCNGAYTCNACNGAYCAYTAYATHAARYTNAAYAAYYTNMGN ATHGGNCARAGYTAYTCNGCNTTYATHGTNTGYAAYMGNACNACNAARACNMGNATHATH AARTTYACNTAYGGNGCNTTYTGYGARGAYAAYAGYGARCAYGGNGARAAYACNACNATH CAYGTNAARGARAAYGTNACNGTNGARGTNYTNMGNTCNAAYGAYATHAAYACN------ ------GTNGGNYTNTTYACNGCNGTNATHTTYTCNTTYATHGCNGTNGTNYTNATHGTN AGYGTNGCNTAYTTYATGTGGAARAARTAYCARCAYMGNCARMGNATHYTNMGNATHTTY MGNCARGARCARAAYGAYCCNTTYCARGCNYTNTAYATHCCNGCNCARGAYGTNTAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MGNGARTTYTCNTCNATHMGNCAYATGAARACN GGNAGYACNAGYGCNATHGAYATGGCNMGNAARYTNTCNGTNGARGARGAYYTNYTNACN CARGTNCARGGNYTNGGNGGNGARAGYTCNGAYGAYTCNAARGARGARGTNMGNYTNTGG CAYGTNGCNCCNCARAARMGNGARTCNAGYATGGAYAGYTAYGAYGAYGAYGAYATHGCN GAYGCNMGNAGYAARACNGAYTAYMGNCCNGAYGARGGNGAYGAYGAYGAYGAYGAYGAR AAYGAYTGYGGNGCNGTNGGNGARYTNYTNGAYGARGCNYTNATGTCNGAYTAYAAYCCN GAYATGGAYCCNAAYAAYGTNGTNYTNMGNMGNAARCCNCARCARACNCCNGCNGARGAR TAYGAYCCNGAYATGGAYATHAAYAAYGTNGTNYTNMGNMGNAARCCNMGNCCNACNAAR ACNMGNAGYCAYGCNATGACNATGTCNACNACNGAYGAYGAYGAYGAYGAYGAYMGNCCN TAYAGYYTNTCNGCNTAYMGNAARAGYGTNAAYGTNAAYCARCAYCAYATGGARCCNGTN GTNMGNCARAGYAARTAYCARGGNCARCAYGTNGTNGARGARGAYATHCCNATGCCNTCN GCNAGYMGNMGNTGYAARGAYGAYACNMGNGCNGTNCARGAYMGNATHAARGARYTNCAR GARYTNGTNCARCAYGARCARAAYGTNATHATGCARACNAGYAAYGCNYTNAAYAARTGY TGYGTNGGNAAYGCNTAYTTYGCNGGNTCNGCNGARCARGTNGARTGYAAYMGNYTNYTN YTNATHTCNTGYCARAARMGNCARGTNTAYATGAARGARATHCARMGNYTNAARCARACN TCNATGYTNGAYGCNTCNGCNCCNGGNCCNMGNGGNTCNYTNACNATHAGYGAYATHMGN YTNCCNYTNAARAARGAYTTYGTNAARMGNATHGGNACNTCNCAYGAYAAYACNACNCAY TTYTTYATHYTNYTNATHMGNAAYGGNTGYCARGTNATHTGYACNCARATGYTNTCNACN CAYGAYTCNATGATGMGNGGNAGYYTNGAYTTYCCNAAYYTNATHAARATHAAYGGNATH AGYGGNGAYTTYAARYTNGCNGTNGAYATHTAYGGNATGAGYGTNTCNMGNGARATGACN AARGAYAARAARAARAARACNCCNAARAARGGNAARGGNTAYGCNACNGCNYTNGARAGY CCNGGNGGNCCNATGGCNGTNMGNACNACNAGYTTYAGYCAYGTNGCNTGYGTNGAYYTN AAYATGMGNTGYYTNGAYAARACNTCNTTYCAYYTNGAYMGNYTNCCNCAYYTNTCNCCN YTNTAYGGNCARATHTTYATGMGNTTYAARTGYYTNATGGARTCNCAYGTNGARGARAAR GGNTTYYTNACNATGTTYGAYGAYGTNAGYGGNTTYGGNGCNTGGCAYMGNMGNTGGTGY GTNYTNTCNAGYAAYAARYTNTGYGTNTGGAARTAYCCNGAYGAYGARACNMGNAARGAY CCNATGACNATHATHGAYYTNAARMGNTGYGTNACNGARAARGTNGGNYTNGTNCCNMGN GAYATHTGYGCNMGNCCNAAYACNTTYGARATGGTNACNGTNMGNCARCCNYTNAARGGN GARCAYGAYACNYTNATHACNMGNACNCAYAGYACNATHACNACNGTNMGNCAYCARATG TCNGCNGAYACNAARGARGARMGNATHATGTGGTGYAAYAARATHAAYMGNACNYTNTCN AAYYTNMGNACNTGGAAYCCNGAYGCNYTNCAYCCNTCNAARGAYTTYCARTCNTCNATH YTNGGNACNCARGARTAYTGGAAYGAYGCNTAYGARAARGARYTNGARAAYTTYGARGAR ATHGGNGAYGTNGGNGARATHTGGTTYGGNGARGAYACNCARAAYMGNATGGTNMGNTGG ATGTGY---GARACNTGYATHCCNAARTCNTCNAARATHATHGAYYTNGGNTGYGGNAAY GGNACNYTNYTNYTNGCNYTNMGNCARGARGGNTTYTCNGAYYTNACNGGNGTNGAYTAY TCNGARAAYTCNGTNAARYTNGCNAAYAARGTNTGYGARGCNGARGAYGTNAARGAYATH ACNTTYGARGTNTGYGAYATHYTNTCNTCNTCNCARGCNGARGAR------MGNAARAGY YTNTAYGAYATGTGYYTNGAYAARGGNACNTAYGAYGCNATHAGYYTNAARAAYACNGAY GAYCCNCARGAYMGNCARACNTAYATHGARCAYGTNTGGTCNATGYTNAARCCNGARGGN MGNYTNATHATHACNTCNTGYAAYTGGACNAARGARGARYTNACNCARCAYTTYTGYAAR GCNTTYCAYTTYACNGAYGARATHCCNGCNCCNAARTTYACNTTYGGNGGNCARACNGGN CARAARGTNACNACNYTNATHTTYACNMGNAARGCNCARATHATHGTNTTYCCNGARGAY GGNYTNTAYGGNATGATHYTNAARACNAARCARGCNATHTTYCCNTTYYTNGARAARATH GCNGAYCCNAARGTNACNCARTGGAAYCCNTGYTCNGAYCCNACNMGNTTYCCNGAYACN GARGTNCARCAYGCNYTNAGYTGYATGGCNAARGARAAYGGNATHTAYYTNGTNGCNAAY ATGGGNGAYMGNGTNCCNTGYAAYGTNACNCARGAYCCNAARTGYCCNCCNACNGGNCAY TAYCARTAYAAYACNGAYGTNGCNTTYAAYCCNGAYGGNCARYTNGTNGCNMGNTAYCAY AARACNCAYYTNTTYTTYGARCCNCARTTYGAYACNCCNAARCCNGARGTNGTNTAYTTY GAYACNCCNTTYGGNMGNTTYGGNATGYTNGTNTGYTTYGAYYTNYTNTTYCARAAYCCN GCNGTNACNATGGTNACNGAYCAYGGNGTNACNAAYATHGCNTTYCCNACNGCNTGGATG GAYGCNATHCCNYTNYTNTCNGCNATHGGNTTYCAYTCNTCNTTYGCNMGNGGNYTNGGN ATHAAYTTYYTNGCNGCNAAYATHCAYYTNCCNGCNTTYMGNTTYCAYGGNAGYGGNATH TAYACNCCNGAYGGNATGGCNAGYTAYTAYTAYTCNAAYAAYCCNYTNTCNCCNGGNAAR YTNYTNGTNTCNACNGTNAAYATHATHAARTCNAAYTCNACNGARAARCARCARGARGCN AARMGNAARGTNGTNGAY------------------------------------------ ------------------------------------------------------------ ACNATHGCNGGNAARGCNAAYACNAAYAAYAGYACNGGNGAYGARTTYGARGCNAARYTN TTYGAYGAY---ACNTTYACNTTYAARCARYTNGARGAYTCNTCNGGNMGNYTNGAYGTN TGYCARAARAAYGTNTGYTGYTCNATGACNTAYMGNTTYGCNGAYAAYACNAAY---TCN GARYTNTTYGCNTTYGGNGTNTTYGAYGGNYTNCAYACNTAYGARGGNCARTAYTAYTTY CARATHTGYGCNYTNGTNAARTGYGAR---AGYGAY---AAYMGNAGYTCNTGYGGNGCN CCNACNACNATHTCNAAYACNATHTTYGAYTCNYTNTCNATHTCNGGNCARTTYCARACN AARTTYGTNTAYCCNCARATHATHATGTCNCARAAYGGNCARYTNACNYTNGGNGAYAAR AGYTCNTGGAGYTTYCARGARACNATGACNATGACNTCNGGNCCNGGNYTNGAYAARCCN YTNATHGCNGCNGCNYTNTTYGGNMGNTCNTAYTGYMGNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNGCNGTNGARAARTTYGGNCARGAYGARAARGARGTNYTNGAYCAYYTNTTYGCN GTNGAYYTNYTNGTNGARAARAARTAYGCNCCNATHCAYGCNGARGCNGCNYTNCARTCN TGYAARAAYGAYYTNACNAARGCNGARAARTTYYTNCARYTNCARGTNCARYTNGARCAR YTNGGNTTYAGYAGYGAYACNGTNMGNAAYGCNYTNGTNACNTCNGAYATGGAYCAYGAY AARGCNYTNGAYATHYTNACN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNGGNTTY ACNGARGTNAARTGYCAYYTNATHAGYGCNTTYMGNAAYAAYGAYTTYCAYMGNACNYTN TGYAARATGATGCCNAGYAGYGTNTGGACNYTNAAYGAYACNAAYACNGAYGAYAARCAY GAYAARAARGARAARACNGAYATHGGNAGYAGYGARYTNGAYGAYGTNACNTAYGAYYTN YTNAGYTAYTTYYTNYTNTTYGCNGTNTCNGAYYTNGGNATHTCNAARGARTCNATHAGY AARAGYGGNTTYAARATGATHACNTGYMGNMGNGGNMGNTGYATHACNGGNGARACNGCN GARATHGTNGCNACNCCNTTYGGNTCNYTNTGYCCNGTNGTNTTYTAYAAYGGNTAYAGY MGNGGNGTNATHAGYAAYGTNGGNGGNATHAAYGAYTGYTGGATHGTNACNGAYGCNMGN TGYATHCCNGGNTGYGARGGNGGNCCNYTNTTYACNAARMGNAARYTNATHGAYAARGAY AGYTTYYTNACNGGNATHATHACNTCNCCNYTNTGYTGGAARAAYAAYGARTGGGTNGGN TTYTCNATHGCNTGYAGYATGGAYAGYATHYTNMGNTCNATGGTNCARCAY--------- ---CARGARGCNTTYTCNAAYYTNGGNAARAARCCNATHTCNATHTCNTCNACNMGNAAY CARAAYAGYTCNCAYGTNATGCAY---CCNTCNATGMGNMGNATGAARGCNCARGCNYTN ACNGTNYTNATHCARTGYGGNAGYACNTGGGGNACNGGNGTNATHGTNAAYMGNGAYAAR GGNGTNATHYTNACNTGYAGYCAYGTNGTNAARGGNGCNGAYYTNTAYTCNGTNATGGTN ACNCCNTCNAARAGYACNGTNCARCAYAARGCNGGNGTNGTNTAYMGNCARGAYCCNGTN AGYACNGCNTAYGAYYTNGCNGTNYTNAARTGYCCNCARGCNACNAARCAYYTNCCNAAR GGNTGGTGYGTNCCNYTNGCNCAYGCNMGNGTNGGNGAYGAYATHATGYTNTCNGGNCAY GCNGTNTTYAGYACNGAYAARAAYYTNGARCCNTCNATHTGYCARGGNGTNGTNTCNAAR GTNATHGGNAAYCAYGGNAARCCNGTNYTNGTNCARACNACNTGYGCNGTNCAYGCNGGN ACNAGYGGNGGNCCNYTNYTNACNYTNGGNGGNTGYYTNGTNGGNATHGTNGTNTGYAAY ACNMGNGAYTCNGCNAGYAAYACNAGYTTYCCNCAYGTNAAYYTNTGYATHCCNATHTCN GCNGTNTGGCCNGTNGTNAAYAAYTAYYTNTCNACNGGNGAYAARGCNTGYYTNTCNCAR YTNCARGTNMGNGAYAARGAYYTNAAYCARYTNTGGGCNYTNGGNGCNCARACN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNMGNTAYCARGAYYTNGAYGAYCCN GARTTYAAYAGYTCNTCNTCNATHGGNGTNCAYAAYATHCCNAARATGCAYATHTCNAAY ATHAARGCNGTNGARGCNGCNGGNATGMGNCCNGTNTCNTCNACNCCNGGNYTNYTNCAR ---------------CCNMGNGCNCCNCCNGGNGCNGCNACNYTNTCNTCNMGNCARCCN YTNGCNYTNTCNCARCARTCNTCN---------TCNGGNGCNGTNAARMGNMGNCAR--- CCNCCNGTNGCNCARGARGTNGGNGGNCCNYTNMGNYTNGGNAARGGNGGNGGNCCNGGN ATHGGNGAR---------GTNGTNTCNCCNCCNAARMGNGCNMGN------CCNGGNATH CAYCCNGCNGARCCNATHGARATHYTNGAR---GARGAYAAYTCNAARTTYGTNAGYCCN ATHCARGGNTTYMGNGTNGTNGTNACNAAYYTNTTYTCNGGNGTNACNCARGAYGAYATH ATHGARYTNTTYGGNGTNGTNGGNCCNYTNAARAARGCNMGNYTNYTNAARGCNGGNTCN GCNGARGTNGTNTAYACNACNMGNGARGAYGCNTCNAARGCNGTNACNAARTAYAAYGGN MGNGARYTNGAYGGNCARCCNATGCAYGTNAARATGACNACNCCNGCNACNGCNGTNGTN ---AARGCNCCNGTNTCNCAYGAYCCNGAYATHACNGGNGARGCNYTNMGNYTNTAYAAR AARCCNAGYAGYYTNGGNGCNYTNCCNGARGCNCCNATHGARGTNCCNACNATHCAYMGN GCNYTNTTYAARGTNGGNCCNCCNGCNCCNAAYAARTCNGTNAARTTYACNGTNAARATH ------------------------YTNYTNMGNCARAGYGTNYTNTCNCAYMGNTGGACN GAYACNYTNAARATHGTNAAYGCNYTNGTNAARGAYGGNGAYGTNATGATHGAYACNATH TGGAARGCNGGNACNATGGCNYTNGTNGTNGARAARAARTCNAARTTYGTNMGNYTNTTY YTNMGNCARGTNCARMGNGTNTCNGAY---TGYMGNYTNGAYGTNYTNTTYGAYCAYYTN YTNTAYYTNYTNTAYGARAGYGAYTTYGARGAYATHAARGAYYTNCARTTYMGNATHAAY AARATHAARTTYAGYGARGAYCCNAAYGARCARTAYATGAAR---------GCNYTNTTY ACNGCNTAYYTNGGNYTNATHGAYTAYGTNCARTGGAGYAARAAYGTNACNGARGAYGTN AARGAYGARACNGAYATHATHATGATHTGYTCNCARGTNAGYCARGARYTNTCNGCNCAY GCNGAYAARGARACNGCNATHMGNGCNATHGARAARATGTCNAGYATHAARGAYATHCCN GGNGTNTGGGAYATHTTYATHGTNAARATHGTNGARATHCAYGARTTYTAYGAR------ GCNGAYGCNMGNYTNGTNYTNGARGARTAYAARMGNYTNAAYCCNGAYAAYCCNAAYGCN CAYMGNTAYCAYYTNGARTTYGARAARAARCAYGGNGARMGNMGNGAYCARGCNYTNYTN AGYATGAARAAYATHGTNMGNYTNGAYCCNAGYAAYCCNATGGCNYTNAARYTNTAYGAR GARYTNGCNTCNTCNGAYCCNGAYGCNGTNTCNATHYTNTTYAAYTAYYTNGAYTTYGAY CAYTGYAARGAYGAYYTNAAYGCNTGGATHYTNYTN---------TGGAARCAYYTNCAY GARGGNATHGGNAAYGARGGNGCNGTNACNACNTGYTGGACNTCNMGNAARGAYTGGTGG CCN---------------------------------------------------GAYTGY AARAARTCNGCNGAYAARTGYTCNACNTGYAARGARATHGTNGAYAAYTTYCAYAARGGN YTNYTNGCNACNGCNAARTCNAAYTAYGGNGGNGGNAAYACNAAYTGGGARGARAARTCN YTNGGNTCNTAYGCNTTYAGYGARGTNMGNYTNGTNGARATHGTNGARAAYYTNTGYAAR GAYAARTCNAARGARTGYCAYACNATGYTNGARGARCAYGARGAYYTNGTNGARAGYTTY TGGTTYAARGARTTYGCNAARAARACNGAYACNGAYTTYCAYACNTTYYTNTGYATHGAR AAYATHAARGTNTGYTGYCCNAAYAAYACNTTYGGNAARGAYTGYCARCCNTGYGCNGGN GGNGTNGARMGNCCNTGYCAYGGNAAYGGNAARTGYAAYGGNGARGGNACNMGNGGNGGN ACNGGNAARTGYMGNTGYAAYGCNGGNTAYGCNGGNGAYYTNTGYGAYGARTGYAARGAY GGNTAYTAYGCNGAYAGYAARAAYGARGCNCCNAGYGTNTGYAARGTNTGYCAYATHTCN TGYAARGGNAGYTGYTCNGGNGARGGNCCNCARTCNTGYGAYGARTGYAARGAYGGNTGG YTNTCNGAYCCNACNCAYGGNTGYAARGAYATHGAYGARTGYYTNGARGARCCNTGYGAY GAYGAYCARTAYTGYACNAAYACNATGGGNTCNCAYTCNTGYTTYAGYTGYAAYACNGCN TGYGCNTCNTGYACNGGNGCNGGNCCNGAYAARTGYAAYGARTGYAGYAARGGNTAYATH AARTTYGAYAAYGGNAAR---TGYGARGAYCARGAYGARTGYAGYYTNGAYCCNACNYTN TGYACNAARCCNAAYGARGARTGYATHAAYACNCCNGGNAGYTAYGARTGYATHTGYTCN ACNGGNTAYGARTAYAAYGCNGAYAARGAYTGYACNAARACNCCNAARGAR--------- ------------------------------------------------ATGGGNGGNACN GARAGYAARMGNAARATHGTNGTNGARGAYGTNAAYGGNGARGGNGTNGTNCARGTNACN GAR---GCNGTNGTNMGNMGNATGAARGGNCARCCNGAYCCNCCNGTNCARAAYGCNTCN AAYTCNAGYGCNGAYCAYMGNGTNCCNGCN------------------------------ ---------MGNGAYATGACNGARGARATHGARAAYTTYTAYATGGARAARYTNAAYGAY YTNCARMGNAARACNGCNGCNYTNCARGARCAYTCNAAYGARCARTTYTCNAAYGCNGTN AARGARGTNGARGAYAARTTYATGAARTAYACNACNTCNCCNGTNTGYCARGAYYTNCAR ACNAARGTNYTNGARTGYTAYCARTCNCAYCCNCARTCNATHYTNGAYTGYTCNTCNGTN GTNACNGCNTTYTCNACNTGYGTNGAYMGNGCNMGNATG--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARGCNGAYACNATHACNMGNATGAGYMGNYTN TGYGTNGARAGYGGNYTNYTNTCNGARGCNAAYGAYYTNATGMGNCARYTNACNGTNYTN CAYTCNAGYCARGGNGAYGTNGARAARGARATGCARTCNMGNGTNGARMGNTCNAAYYTN YTNYTNAARATGMGNAARGCNCARGARGCNGARGARGTNGCNGAYGARTGYTTYAARYTN YTNGARAGYAAYACNCCNTCNYTNACNTTYGCNAARATGTAYAGYGAYYTNTCNGTNGCN TAYACNCARATHYTNCAYTAYGAYAARGCNGTNCARTGYAGYGARAARGCNYTNCCNYTN GTNGARGAYCCNTCNGGNGAYCCNMGNYTNGCNGCNGTNATHTAYCARAAYTTYGGNGCN ATHTAYAAYTAYATGAAYMGNTTYGARGAYGCNGTNAARTAYCAYGARAARGCNTGYCAR ACNTTYGCNAARYTNGGNATGMGNGCNAAYCARGGNCAYTGYTTYACNAAYATGGGNTAY GCNTAYAGYCARYTNCARGAYATGGAYAARGCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNCCNGAYTCNTGGCAYCAYCARATGGTNTAYGGNGTN AGYCAYCARGGNYTNTAYYTNACNAAYCCNYTNGARATHGTNTCNGARMGNTCNACNGTN AARCARYTNCAYAGYGAYTCNGTNYTNYTNGTNMGNMGNCARGAYATHGTNTCNMGNTTY MGNGARTCNACNGAYYTNGGNCARYTNYTNGAYCAYCCNGAYCCNMGNTGGATGTCNATG AAYGTNYTNGGNCARGTNGTNAAYGTNYTNMGNGARTGYAAYATGCCNTCNGTNCCNGGN TAYMGNYTNCARGTNACNTCNCAYGTNAARATHCCNGCNTCNTAYCARGCNGGNATHACN YTNTTYATGMGNAARGARCARCCNGCNTGGAAYGCNYTNGTNACNGCNTCNGARYTNCCN YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARYTNGAR GCNGARMGNATHGTNGTNTTYACNCCNTCNMGNMGNGTNGGNGGNACNMGNATHGTNTGY TAYGAYGAYMGNTAYATHYTNAARYTNGCNGTNGARATGAAYGGNATHGTNGTNTCNAAY GAYGTNTAYMGNGAYYTNCARMGNGARAAYGAYTCNTTYAARGARGTNGTNGCNAARMGN YTNYTNATGTAYTCNTTYGTNCARGAYATGTTYATGCCNCCNGARGAYCCNYTNGGNMGN GARGGNCCNTCNYTNGAYAAYTTYYTNMGNATHMGNCCNTCNGARCCNAARAAYAARCCN CARATHTGYCCNTAYGGNAARAARTGYACNTAYGGNAAYAARTGYMGNTTYTAYCAYCCN GARMGNMGNTAYACNTCNCARAARATGGTNGCNGARAARYTNAARGARAGYGCNGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TCNACNGARGCNATHGTNAARGAYGCNATHATH MGNTTYACNGARGAYGAYTAYAARAAYATGGAYAGYTTYYTNGCNGAYCARATGYTNGAY AARGCNAARGARAARACNACNYTNMGNAGYGGNATHAARTAYACNGTNGARGTNTCNCCN YTNGARATHGCNGAYYTNGCNCAYCCNTCNYTNCARCARYTNATHCARYTNCAYCCNACN ATGTCNYTNATHTTYAARCAYCARACNGTNAARTTYMGNAARAARAARGGNTTYGCNGAR GCNGTNTTYTCNACNATGACNGARYTNAARGARTTYGTNTAYCARYTNACNCARATHAAR GTNGTNGARAARMGNGTNGAYGTNACNATH---------------AARGCNATGGAYCAR TCNGGNACNYTNGTNATHCAYYTNAAYMGNAAYGCNAARYTNATGAARYTNYTNGAYTCN GGNGARGAYCCNATHCCNATHGGNGARAAYCCN---------CAYAARATHAARTTYGAR ------AARGTNCCNAGYATHGCNAAYGGNGCNTTYATGCAYAGYATGTTYCCNTTYACN AAYAAYGTNYTNATHACNMGNAGYCARGTNGGNAARGAYAARAAYTCNATHTAYCAYGGN CCNGTNTCNGTNTTYTAYATHAAYTCNAARTGGYTNGARGCNGTNATGGAYTGYTGYTCN GAYTTYGCNGTNAAYGGNTTYCCNYTNAAYGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CAYYTNGAYCCNGCNGTNTCN ATGGCNGCNGARGGNCCNCARAGYATGATGGCNTGGCARGGNGAYAGYACNAAYATGATH GAYMGNTTYGAYGTNMGNGCNAAYYTNGAYATHATHACNGARTAYAAYCCNAGYMGNGCN TCN---AGYGCNACNAAYGTNAAYGARCAYGAYGARMGNYTNGCNAAYTAYGARMGNTAY MGNACNYTNGTNGARAAYGARGCNGCNGGNYTNTCNGARGARCAYTCNYTNCAYCARATH TAYYTNGAYGARCAYTTYGGNACNATHAAYAARCCNAAYGARGARGARAARAARAARAAY GCNGAYAARAARGCNGCNATHGGNTAYGTNTAYGARGAYAGYACNCCNGTNGARAARAAR GARCCNGARGARGARAGYGARGARGARAGYGAYGARGAYYTNGAYATGGCNGAYYTNGAY GTNACNATHGAYGTNGAYAGYYTNACNCCNGAYATGTGYACNGARGTNAAYGGNATHGCN TGGCARTAYGGNATGGCNGARGAYGAYTTYGTNMGNYTNYTNMGNAARGAYAARGARGAR YTNGARGCNYTNAARGARGCNMGNCARYTNGARGARGCNAARGCNCARTTYTCNGGNMGN AARTCNMGNMGNGARMGNMGNGCNATHAAYGARAARMGNCARAAYCCNCARMGNTTYTGY MGNCCNAGYTAYGCNGCNMGNGAYAGYCCNAARTAYGARCCNTAYAARMGNCCNTTYTCN TCNTCNMGNTCNMGNTCNMGNTCNMGNTCNMGNTCNTCNGARMGNGCNGARGTNAARTTY ATHACNAGYTTYGGNGGNAAYGAYAGYGAYGAYGAYGGNGGNGGNATHGTNCARGGNCCN TCNYTNCCNTCNCCNGCNGCNTCNGCNACNGCNTCNGAYCARAARAARATHTCNGARCCN TCNAARTGYGARACNCCNTGGYTNTCNTCNCCNCCNMGN---------AAYGARTCNAAR TCN---------GARAAYTCNAARTCNCARACNTCNMGNCARMGNCARAGYAGYMGNTCN TCNACNAGYMGNTCNMGNTCNMGNTCNMGNTCNMGNTCNTCNYTNMGNCAYMGNGGNMGN MGNTCNMGNAGYMGNMGNCAYTCNTTYAGYTCNTCNTCNAGYMGNTCNMGNAGYMGNTCN MGNAGYMGNTCNMGNTCNCARTCNTCNMGNAARGAYTCN--------------------- ------------------------------------------------------------ ------AARGTNGAYAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNYTNTGGGCNATHYTNAAR YTNGARCARCAYGARAARGCNAGYAARCARGCNGGNGARTGYYTNGTNTCNYTNAGYGGN GTNGARGCNMGNATHGARGAYMGNYTNAARGCNTAYAARGCNAARACNGTNACNGAR--- ------AGYGTNGAYTAYAGYACNYTNMGNGARACNGGNATGGCNTGYCAYCARATGMGN ACNTGYYTNGCNGAYGTNTCNMGNATHATHTCNYTNGCNMGNATHACNGARYTNCCNYTN GTNGGNGARCCNGGNMGNGTNTGYGAY------------TCNGARAAYGAYAARYTNMGN TCNGARYTNTCNGARYTNAARTCNAARTAYAGYGTNYTNGARAGYACNYTNAARGARCAR CARGGNAARYTNACNGTNTCNAARCARMGNCARMGNGAYTGGGARCAYTCNGTNTGYMGN CAR---------AARAGYAARMGNTCNMGNAGYYTNTCNGARTCNTTYGAYGAYYTNAAY ACNATGGARAARGARYTNGGNGARTCNTCNGAYGAYMGN------------GARYTNGCN GAYTGYMGNGARGTNGAYCAYGARMGNATGATGCAYATHAAYAAYAAYAARATHYTNAAY CCNGARAARMGNTCNCARTAYGARCARATHAARMGNGCNTAYGCNGAYATGYTNTAYAAR TGGGAYYTNYTNAAYCARMGNGCNCARATHYTNAARCAYACNGTNTCN---YTNCARCCN TGYAARAARATHGARTTYTCNATHCCNTGYTCNAAYTGYTCNGAYACNGTNATGAAYGTN CARTGYAAYMGNTGYCAYTAYCCNTCNYTNAAYTGYTCNATHTGYCAYATHGGNGTNMGN GGNCCNGCNAAYGTNTGYYTNGCNTGYGGNCAYGGNGGNCAYTCNAGYCAYATGATGGAY TGGTTYCAYTCNAAYAGYCARTGYCCNAGYGGNTGYGGNTGYCAYTGYYTNCARGARAAR GCNGCNATGAGYAGYGCNAGYTCNCCNAARMGNTCNGARAAYGAYMGNAGYAAYAAYMGN GCNAGYGGNTAYACNYTNGAYTCNGCNGAYAGYTCNACNTCNATHGTNAAYACNAARTAY GAYATGAARYTNYTNAARCARAAYCARMGNYTNYTNAGYGARGTNGARMGNYTNGTNGGN GAYATHCAYGCNGCNAAYCARAARAAYGCNGTNYTNGTNAARGAYGCNGARAARGCNAAR ATHGTNTCNGARYTNGARGAYMGNTGYTCNGGNYTNYTNGCNGARAAYCARGCNCARGAY AARGCNYTNMGNAAYGCNGARMGNCAYYTNGAYGARGGNCARMGNMGNATHGCNGARYTN CARAARMGNYTNGGNCAYGTNGARGCNGARYTNGTNGAYACNAARGCNGARYTNAGYGAR GTNAARYTNGTNAARAARGARGTNGARAGYCARMGNGAYGARGCNYTNCAYAAYYTNAAY GAYACNCARGAYTCNYTNGARGAYTAYCARAARMGNACNAARGAYAARATHMGNAARATG GARGARCARGARGAYGARYTNCARGARTCNYTNACNGCNGCNACNCARGARMGNGAYGAY YTNYTNGAYCARYTNTCNTCNATGGARATGTCNYTNGCNTCNCARGARGCNCARATHAAY MGNYTNYTNAAYGAYGTNAGYTCNGARGAYTCNMGNTCNCARGARYTNGCNCARGCNAAY CARCARYTNAARGCNCARYTNGAYCARYTNACNGGNCARATHGTNGAYYTNGARAARAGY AARATHGARGGNAAYGTNATHAARAARGARMGNGAYGAYYTNMGNYTNGARYTNAARGGN CAYMGNACNATGGCNMGNGAYATGAARGCNYTNYTNAARYTNYTNCARCARACNACNGCN CCNAAYACNGCNGAYGAYAGYGGNAAYTTYAGYTTYAARTCNCARCCNACNGCNGAYTAY CAYAGYATGATGCCNGCNATHCCNATHATGGAYATHAARGCNGCNGARYTNAAYTGYAAY AAYAAYGGNYTNGGNAAYTGYGARCCN------------------ATGGTNTGYGARATG MGNAAYYTNGTNACNAAYATGGAYTGYGARATHCARMGNYTNMGNAGYGAYYTNAARCAR MGNGAYGCNGAYGAYMGNACNTAYGCNAAYYTNMGNGAYGARYTNAARGTNYTNATGGAY AARGTNGARAGYGGNATGTGYCAYAAYCARGARYTNGARTAYYTNGTNGCNTCNYTNGAR TGYGAYAARAARAAYYTNATGAARAARYTNGARGARACNYTNAGYTGYYTNGARGARMGN GAYMGNACNATHCARTGYYTNGARACNMGNYTNAAYGARMGNAGYGTNCARATHGTNTGY YTNCARGARGAYGTNGAYGARMGNAAYTGYMGNATHTGYTCNYTNGARGGNAARYTNCAY GARATHGARAARMGNATHAAYTCNGAYGCNACNATHGCNCCNAGYCCNGCNYTNAARGAR GCNTGGGCNMGNATHAARGARYTNGARGCNATHYTNYTNTGYAARAAYAARTCNATGGAY GARYTNCARGARAARYTNGCNAAYTCNYTNMGNGARYTNMGNGTNYTNAARACNGARTCN GARAARGARATHGARTGYYTNMGNAAYCARGAYGAYGCNMGNACNCARGAYATGGARAAY ATGAARGARGARATHGARTCNGGNMGNACNAARYTNTCNACNTGYCARAARGTNATHGAY GAYYTNAARMGNACNAAYMGNAAYCARATGGAYAARATGGAYTGYATHTAYCAYGARYTN GARGARGTNAARTAYGCNAARGARAARATGGARAGYYTNYTNAGYGGNCARYTNGARGCN ATGGARAARAAYTTYAARACNTGYCARGAYCARAAYGCNAAYYTNGARAAYGCNYTNGCN YTNTGYMGNAAYGARGTNTGYACNCAYYTNAARACNATGGARGAYATHMGNAAYACNTAY GARGCNGARYTNGARCARMGNGAYTCNTGYATHMGNAARYTNAARGAYGAYYTNMGNMGN ACNGTNGARGARYTNAARTGYAARATGGARGAYAAYACNTCNYTNGARMGNTCNYTNGCN GARTCNMGNAGYAARGTNCARCARATHTGYTGYCARYTNAARGARGCNGAYACNAAYATH CARTGYYTNAAYATHAARGTNCARGARATGGARAARYTNATGYTNAARGARAARTCNGCN TGGATGAARGAYTCNGARGARATGGARMGNMGNYTNACNCARGCNTGYAGYAAYYTNGCN ATGGCNAAYAAYGARATHGAYACNYTNAARCARCARYTNGGNGARAARAARATGGCNATG GAYTGYYTNCARACNGARAARGCNCAYATGTGYGGNGARATHAARAARYTNAAYGAYCAR ATHTGYTGYCARCARGARCARYTNAARAARATGGARACNGAYAAYCARGARYTNTGYMGN CARYTNCARCARAARATGGARTGYATHMGNGAYYTNGARAAYYTNGTNMGNACNAARGAR CAYGARYTNAARTGYYTNACNAARTAYGTNCARGAYAARGARTCNCAY------GCNGAY AAYAGYATGCARATGAARYTNGARAARGARAAYGCNAARYTNAARGARTCNYTNGAYMGN TGYCARGARGARAAYAARTGYAARTCNACNATGYTNTGYGARTGYGARGARGCNTTYAAR CAYTGYCARYTNYTNAGYCARGAYAARGAYAAYGARATHGARYTNYTNAARTGYCARATH GAYACNYTNAAYGARAARYTNCARGAYMGNATHGCNMGNGTNGAYGARYTNGARMGNGGN ATHGARAAYYTNCAYAARGAYGTNGARMGNMGNATGCARMGNGTNGAYGARCARYTNAAR AARTAYGARACNGARYTNGTNGAYMGNATHCARGARATHGGNACNYTNAARGARTGYATH AAYACNTGYCARYTNAAYYTNACNGARAARGARAAYGARYTNAGYCARCARGTNCARAAR AAYTGYGTNGTNTCNACNGARYTNAAYTCNATHCARYTNAARYTNAARGAYGCNGARGAY ACNMGNGAYCAYYTNGGNTCNCARYTNTCNGARAARAARGGNGARGTNGCNGAYYTNACN CARCARYTNMGNYTNAAYMGNGARCARATGCARAARCARCAYGAYGAYYTNGTNCARTCN MGNCARGCNYTNTCNTGYGCNCARMGNGAYGCNGAYAARYTNMGNMGNGARYTNGAYGAY GCNYTNGCNAGYYTNGARCAYMGNGARTGYGARATHACNMGNYTNAAYGARGARMGNAAR YTNYTNATGGARAARGTNGCNTCNYTNTCNTGYCARATGGARCARGARACNAGYATGYTN AARCARCARATGTCNGARACNAARTGYMGNYTNGARAARGARYTNGARTGYYTNMGNAAY TAYATHTGYAARYTNGARTCNAAYAAYACNTCNYTNTGYCARAARGTNTCNYTNYTNCAR MGNCARATGATGCARATGGARAARTGYTGYCAYCARAARYTNGARTCNYTNAAYMGNAGY YTNGAYGARYTNAARACNAARYTNGCNGTNAARGARGAYGARYTNYTNTCNATHAARGAY AGYATGGAYYTNAARGAYTCNGARYTNCAYMGNYTNAARATGMGNYTNTGYAAYGTNGAR AARGAYTGYTCNTTYAAYAAYAAYATGGARAAYGGNMGNGAYGTNGTNGTNGTNGGNTAY AAYAARGAYGAYYTNGTNATGGARTCNAARAGYCAYATHYTNGCNAAYGAYATGGGNCAR AAY---------------------YTNTCNGARAGYAAYGCNGARAAYMGNYTNTTYGAY GARGARTCNTGYGARTCNTCNCARGCNCAYAAYAGYTCNMGNAAYAGYYTNGGNGTNACN GARGTNCARGARMGNYTNMGNAGYAAYCARYTNMGNCARAARGARATHGARMGNCARYTN MGNTCNYTNGARGARGTNAGYCARGAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYGTNAARGGNTTYAARCCNGGNAARATH TAYGTNGAYAARGGNCAYGTNGTNMGNAAYTAYTTYMGNCAYGGNACNTAYAAYGTNGCN YTNCARCAYTAYAARYTNATHCCNACNGTNAARGTNGTNCCNTAYACNACNTAYAARAAR ATHGGNGTNGGNGARAARGTNCARGCNAARTAYMGNTAYAARGCNGTNATHTGYAARTAY TGYTAYCAYGGNTAYCCNAARATHGAYGTNTAYGARATGAARAARCCNTAYAAYTAYGCN GTNMGNMGNTTYGTNTAYYTNCCNAARGARTAYGAYYTNAAYGGNCAYGGNAGY------ ------GGNAGYGGNCARAGYTAYGGNCAY---------GGNGGNCARGAYTAYGGNCAY GGNCAR---------------------TAYGAYCARTAYGGNGGNAGYGGNAAYGGNGGN TAYGGNAAYGGNGGNGGNTAYGTNTAYGGN---------------------AGYGGNACN GCNYTNGCNGTNGTNYTNTAYAARGARGCNTCNYTNYTNCCNCAYGARAARAARAAYMGN AGYTTYAAYATHGCNGGNCAYGARTTYTAYATHGARCARGAYTGGCAYGTNGGNGGNGTN GCNGCNGTNGTNTGGGAYGCNGCNATHGTNATHGGNGARTAYYTNGCNTCNAAYCCNCAY YTNGTNMGNGARAARAARGTNYTNGARYTNGGNGCNGGNACNGGNYTNGCNGGNATGGTN GCNTCNTCNYTNGGNGCNGAYGTNATHYTNACNGARMGNGARCARGCNYTNTCNTTYYTN GARACNGCNGTNTCNACNAAYACNGGNAAYAARAAYTGGAARGTNAARGTNGARGTNYTN GAYTGG---ACNCAYGAYYTNGAYTCNTCNAAR---TGGAGYCAYTTYGAYYTNGTNATH GGNGCNGAYATHATHTAYATHGARAGYACNTTYTCNCAYYTNYTNAARACNATHMGNTCN GTNGCNCAYTCNCCNACNACNAARATHYTNYTNTCNTGYMGNATHMGNTAYGAYMGNGAY YTNCARTTYYTNAAYATGYTNAARCARTTYTAYACNGTNGARGARATHTTYTAYGAYGCN AARYTNGAYATHAARATHTTYTCNGCN---------------GTNACNCAYYTNGGNGGN TGYCAYTGYGGNGCNGTNMGNTTYTCNGTNACNGCNCCNGCNCAYYTNGAYMGNATHGAY TGYAAYTGYAGYGTNTGYGTNAARAARCARAAYTTYTGYTTYATHGTNCCNAARTCNAGY TTYAARYTNYTNMGNGGNTCNGAYTCNATHACNACNTAYACNTTYAAYACNCAYACNGCN CARCAYACNTTYTGYAARGTNTGYGGNGTNCARAGYTTYTAYACNCCNMGNTCNAAYCCN GAYGGNTAYGGNATHATGCCNCAYTGYATHGAYAAYGGNACNGTNAAYATHGTNAARGTN GTNCCNTTYGAYGGNATHCAYTGGGARGARACNMGNAARACNTCNAAYGTNACNAARTAY TCNAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GTNAARGGNGARYTNTAYMGNGTNGAYAAYGCNATGYTNCAR CAYYTNGAYGAYTTYGARGTNCAYCCNMGNYTNTAYYTNMGNCARGARGCNGCNATHTTY ATGACNCAYGAYMGNGAYGGNAGYGARGTNACNCCNCCNMGNMGNGARGARTGYTGGGTN TAYATHYTNTCNMGNAGYCAYCCNGARATGTCNMGNATGAAYTAYYTNTCNGARTAYGAY TCNGGNGCNCCNGGNACNCCNGCNTAYGCNGAYMGNGCNGAYMGNGAY------GCNAGY TTYGARGAYACNMGNTGYAARTGYGTNTGYTCNAARACNAARGAYGCNAGYGGNAARGAR TCNMGNGCNGTNTTYMGNAAYACNACNMGNAGYGARCARTGYGAYTGYGARCAYGTNGTN MGNCCNYTNGCNCCNACNYTNTCNTGYTCNYTNTGYCARTGYAARACNGARACNMGNAAY ACNACNACNATHAARGTNGTNGTNATHTTYATHATHTGYGTNGTNTCNYTNYTNTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNCCNGTNTAYCAYYTNATHGGNAAY CAYGARYTNTAYAAYTTYAGYMGNGCNTTYTGYYTNMGNAGYCCNYTNAAYAGYGCNYTN ACNACNGARATH------------------CARTGYGARCCNGAYMGNYTNTAYTAYACN TTYYTNCCNCAYCCNAARYTNMGNATHGTNYTNYTNGAYTCNTAYGARATHGGNGTNYTN GGNTAYTCNGAYGAYTCNGARAAYGARAAYTAYYTNAARGGNAARGCNYTNYTNCARGAR AAYAAYCCNAAYCCNAGYGARAAYGAYACNACNGGNYTNGARGGNATGGAYAARMGNTGG GCNGCNTAYAAYGGNGGNGTNGGNGAYAARCARYTNCARTGGYTNTCNCARACNYTNGAR AARGCNCARYTNAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARATHYTNYTN GARMGNGAYGAYATHACNGCNATHGAYAARYTNAGYCARMGNMGNYTNGARMGNATGCCN GTNCARTAYGTNATHGGNGARGTNGAYTTYGAYGGNATGGTNYTNAARGTNGCNCCNCCN GTNTTYATHCCNMGNCCNGARACNGARGARYTNGTNGGNCAYTGY--------------- AARGGNGTNGTNAARTCNTAYGARGGNCARMGNCCNGTNATHYTNGARTTYGGNTGYGGN AGYGGNGCNATHACNGTNGCNYTNYTNAARCAYTTYAARGARYTNCARGCNGTNTGYGTN GAYAARYTNCCNGARGCNTGYGCNYTNACNGARACNAAYGCNGARAAYGTNGGNGTNAAR GAYMGNATHCARATHYTNAAYGGNGAYTTYACNGAYGAYAARATGAARTCNGARATHCAR GCNYTNGGNCCNTTYTCNTTYATHGTNAGYAAYCCNCCNTAYGTNACNTCNGARGARATG CAYGAYYTNGCNCCNGARATHTAYAARTAYGARAGYYTNATHGCNYTNAAYGGNGGNTCN GAYGGNYTNGAYYTNGTNAARCCNATHYTNCAYCARGCNAAYAGYATHYTNATGCCNTAY GGNCAYYTNTTYATGGARGTNGGNGARAGYCAYCCNMGNYTNYTNAARACN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNGARAARCARGTNGCNGARYTNACNAARCARATGGAYGAR YTNAAYAARYTNCCNTCNAAYGARGARYTNYTNGGNAAR---AAYGGNAARGAYTCNGAR MGNCCNATHGCNGAYATGTGGCARTAYATGCARYTNAARAGYMGNGTNGAYGCNAAYGAR GARGGNGTNGGNAARYTNATGTCNYTNGTNGARGAYYTNATGAARGAYATGMGNGAYYTN AARGARTCNCARCARGCNYTNATGGAYAARGTNTCNAAYATHAAYYTNGAYGAYATHTAY AARMGNYTNAAYGAYATGGAYAAYYTNTTYAARGAYYTNGARGAYAARTAYAARAAYYTN GAYACNAARGTNGGNTCNYTNCCNACNTTYGCNGAYATHGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGTTYAARAAR CCNAARTCNAARGCNYTNYTNAAYGGNAGYGCNGAYTCNGTNGAYAGYCARGCNAGY--- ACN------AGYAAYGARAAYYTNTCNTCNAGYTCNAARGARACNAARGAYACNGTNGAY AARATHYTNCAYCARMGNGTNCAYTTYCARGTNTAYTAYYTNGGNYTNGTNCCNGAYATH AAYYTNACNAAYTCNAARAARMGNGAYACNGARGCNCARYTNATHGAYGTNGTNGARGAR AGYCARATHGAYGGNAARYTNCARGTNACNGCNACNGAYGARAAYAARGTNGTNATGAAY ATHTCNMGNCAYGGNATHAARGTNYTNGAYATHGCNGGNAARGARGTNATHCARMGNCAY CCNYTNCAYACNATHGCNCARYTNACNGARTAYAAYGAYGGNTTYGGNMGNCARAAYATH GCNGTNAARATHGGNCARGTNGGNAARACNGTNTAYCARTGYTAYGTNTTYCARTGYCAY TCNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GTNGGNACN GCNATHACNGCNACNGCNMGNGGNCAYAAYGARTTYAARAAYTGGYTNACNTAYGCNYTN ATHYTNGTNGTNATHGTNTGYATHGTNYTNCARYTNAAYTAYYTNAAYAARGCNYTNGAY ACNTTYAAYACNGCNGTNGTNACNCCNATHTAYTAYGTNTTYTTYACNTCNTGYGTNATH GTNGGNTCNGCNATHYTNTTYAARGARTTYTTY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CCNCCNYTNAGYGCNGAYGTNGAR ---GARGAYMGNATHACNATGGARMGNMGNGAYAARCARATHGCNTAYGGNAARAGYACN GARTCNTAYAARYTNTAYGCNAARACNGTNCCNAARGAYCARMGNAGYGTNGAYMGNMGN AARCAYCCNMGNACNCCNATHAARACNTGYMGNTGYAGYMGNMGNAAYTGGGAYGCNCAR ATHAARGCNTGGAARAARTAYACNCAYCARTGGGCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AARATGCCNAAYGGNGAYATHAGYGCNGGNMGNAAR MGNGGNACNAGYYTNTCNAGYACNGAYGGNACNACNCCNGCNAARATGAGYAARATGGTN GAYGCNGCNGCNACNGARGAYTCNTGGAGYAARATGGARGGNYTNTAYGARGAYAARGGN GARGARGGNTCNAARAGYAARTGGGAYACNAGYGAYAGYGARGGNGARGAYGCNYTNCAR AARACNYTNGAYGCNAAYGCNGGNGCNGCNGGNAGYGGNCAYGGNGAYYTNYTNCARCAY ---CARCARAARCCNGTNAAYGGNAARATHCCNYTNGCNAARTCNYTNYTNYTNACNAAY GGNYTNCAYACNYTNCCNCCNGCN------------------------------------ ---------AAYAGYAAYACNCAYCCNTCNTCNAARMGNGARAGYACNGARAARGGNGGN GTNGGNGTNGGNGGNGGNGAYGARGAYAARTCNAGYCAYAARTCNCARMGNGARGGNMGN AGYAARMGNMGNAGYAGYMGNMGNTCNTAYACNTCNTCNGARTAYTCNTCNCAYTCNMGN TCNTAYTCNMGNTCNMGNTCNGGNTCNTAYMGNAGYTAYTCNGAYGAYTCNMGNTAYAGY GAYTCNAGYMGNTCNCAYAGYMGNTCNTCNMGNAGYTAYAGYMGNAGYMGNTCNMGNCAY MGNTAYMGNMGNMGNTCNTCNTCNAGYMGNGGNMGNAGYMGNAGYTAYAGYTAYAGYAGY MGNAGYAGYTCNAGYMGNTTYMGNTCNMGNTCNTAYTCNMGNTCNMGNAGYTAYACNMGN TCNMGNTCNMGNAGYMGNTAYCAYAAYACN------TCNMGNAGYCCNTCNMGNMGNAGY AAYGCNAARYTNAARMGNATHYTNAARTCNCCNYTNGCNATHGTNCCNGTNACNACNYTN ACNGTNGCNCCNGTNACNGGNTGYACN--------------------------------- ------AGYGGNGGNGGNGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GTNTCN GTNAARYTNCCNCAYGCNYTNCCNGAYGAYTTYGAYGCNTCNTTYATHAARTTYTAYACN TTYAGYGTNGAYGAYTGYGGNAAYGTNYTNYTNGARAGYYTNCCNATGMGNTCNMGNGAY AAYYTNGGNAGYGCNGAYGCNTTYTGGGARATHTCNAAYCARGGNMGNGTNTTYATHGCN ACNAARCAYTTYAGYGGNTAYTTYTCNACNATGTGYGARAGYAARTCNAARYTNCCNTCN GTNTAYGCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNACNCCNTTYTTYGARTCNACNYTNYTNTGG GARGARYTNYTNATGACNATGGGNTTYCCNGTNATHMGNGCNTCNGGNGARGCNGARAAR GTNTGYGCNCARYTNAAYTCNGCNGGNACNGTNAGYGCNTGYATHACNAAYGAYGGNGAY AGYYTNGCNTAYGGNGCNACNACNGTNYTNAARGGNTAYTCNGTNAARGAYGCNAARAGY ATHAGYGTNTAYGARATHTCNAARATHATHGARTGYCCNAARYTNMGNYTNGGNCARGAR GARATHATHGCNGCNGCNATGYTNATHGGNTCNGAYTAYTAYGARGGNGTNAARGGNGTN GGNCCNAGYGGNTTYYTNAARYTNGTNCAYGARYTNAARAARMGNGAYGTNACNGAYGTN YTNCARMGNATHYTNTCNTGGAARGARAAYGGNGARYTNYTNTCNATHGTNGAYGAYAAR AARAARYTNGAYGARATGMGNAARCCNTCNCAYTGYTCNCARTGYTCNCAYYTNGGNTCN GTNGGNACNCAYAARAARCARGGNTGYGAYATGTGYGGNACNAAYCARGCNTGYACNGAY ---------------GGNMGNAGYAAYTCNAGYGTNCARCCNTGYTCNTGYGARTAYCAY TCNATHGARMGNAARATHGARGCNTTYTCNTCNGARATHAARGTNMGNGARTCNGCNYTN AARGAYGGNCARTTYACNYTNAARAARGTNATHTCNGARTTYAARAGYAARGARAGYGAY TCNCAY---GAYATHGCNYTNATHATGAARAARCCNGAYTTYCCNAARGTNGTNGARYTN YTNACNGARAARYTNTCNGTNGARGARAARGCNATHAARAAYATHATHCCNGCNYTNGTN AARATGGCNTTYTAYGGNAARGTNCARGAYYTNAARATHGTNCCNYTNAARGTNATHAAR AARTGYCARAARGAYMGNGARCARTGYTTYACNGTNMGNTTYCARAARYTNGARYTNGAY TCNATHACNGAYGARGARGARTAYGARATHAAYGTNYTNCARAGYGARTTYYTNAARAAR TTYCCNGAYYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGGAR GCNAGYAAYATHTCNMGNYTNMGNGARGARCARCARAARGCNATHTCNGARACNGARGAR AARATGGGNCARYTNGARAARTTYAARGCNGAYTAYGARGTNYTNCARAARMGNYTNGAR ACNYTNCCNGAYAARGTNACNCAYGARGTNATGGTNCCNTTYGGNAARYTNGCNTTYATG CCNGGNCARYTNGTNCAYACNAAYGARATHYTNGTNYTNYTNGGNGAYAAYTGGTTYGCN GARMGNTCNGCNAARCARGCNMGNGAYATHGCNGGNMGNMGNATHTCNGARYTNGAYAAR MGNATHGCNGARYTNMGNGARCARAARAARYTNYTNGAYCCNMGNYTNGGNYTNACNTCN GARYTNCARGCNGTNGCNGARGGNAARGGNGAYTAYAARGARATHGTNGARGARTAYGAY GARGARAARGARAARYTNTGGGAYGARCARCAYMGNATHAAYGTNMGNMGNCAYCAYGAR CARATGMGNYTNAARAAYCARGCNAARCCNGARGGNGAYGAYACNAGYAARTCNAGYGGN GAYAARTCNCAYGAYGARGAYYTNTGGTCNMGNYTNGAYGCNYTNGARAARYTNGARGCN GARMGNGGNGARYTNAAYAGYTCNTTYGARTCNGGNAGYGAYGCNGARGAYMGNACNAGY AARACNGAYGARGGNAGYCAYCAYCARGARMGNMGNYTNTCNTCNCCNCCNMGNGAY--- ---AARMGNGTNGARCARMGNGAYAARGARGGNCAYGAYGAYGAYGAYGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GCNGTNACNTTYYTNCCN GCNATHYTNATGATHAGYACNATHATGATHATGGCNACNATHGGNAAYACNATGGTNTTY TAYGTNTAYTTYACNAARTTYAAYCCNAGYTCNACNMGNTCNGCNATHYTNGCNYTNGCN YTNTTYGAYYTNGTNGCNAGYTGYGTNTCNATGCCNGGNGARATHATHGAYYTNMGNTAY TCNTAYAAYTTYMGNAGYGAYGCNYTNTGYAARTGYTTYMGNATGGGNACNACNGTNGTN YTNATHGCNTCNGGNYTNACNYTNYTNGTNGTNGCNGGNGAYMGNTAYMGNMGNATHTGY CAYCCNATGMGNTGYCARATGACNGCNGGNATGGCNAARAARGGNGCNYTNYTNTGYYTN YTNGCNGCNGGNGTNTTYTCNGTNCCNTCNGCNGTNGTNTAYGGNATHTCNAARGTNGAR GGNATHTAYGGNGARGARTGYTCNATHGAYCARAARTAYCAYGGNCAYATHYTNCCNYTN ATHAAYAAYATHYTNCARGGNYTNATHTTYGTNACNGTNTTYGTNGCNATHYTNGTNYTN TAYGGNYTNYTNGGNMGNGTNGTNYTNMGNCARAAYAARTTYGAYAARGAYCAYTCNATH ACNGAYGGNACNMGNGAYTGYCCNCARAAYGAYGGNAGYGTNTCNCCNGTNCCNATHGTN CCNGAYACNCCNGCNGCNATGTCNCCNGAYMGNAARMGNAGYATHTCNTCNGCNMGNCAR ACNTCNTCNAAYGGNGAYGCNMGNACNMGNAARACNACNYTNATGYTNTTYATHATHACN GTNGTNTTYGTNATHAGYTTYYTNCCNCAYYTNGTNYTNAARGGNYTNCARGCNATHAAY AARGAYTTYCCNACNAAYGCNTCNACNTCNGTNACNGTNYTNTAYAAYGTNYTNGTNMGN TCNTAYTTYTTYAAYAGYGCNGGNAAYTGYTTYATHTAYGGNTTYTGYAGYCCNAARTTY MGNMGNGARAGYAAR---------GAYGTNGTNATHGGNTAYCAYGARGAYGAYYTNGAY TTYGTNAARMGNYTNGCNGCNAARYTNMGNTCNAARGGNYTNAGYGTNTGGTAYGARCAR CCNGGNGAYGAYGGNAARAARACNAGYGARGCNATHYTNGGNTGYAARGTNTAYYTNCCN GTNYTNACNGARYTNTCNGCNATHGAYAARGGNATHCAYGARCARYTNTCNYTNGCNTAY ATHTCNAAYTCNGCNATHTAYCCNYTNGGNAARATHMGNTTYCAYYTNYTNGCNCCNAAR YTNAAYGGNGGNGCNMGNYTNATGYTNGCNAARATHAAYTGGTCNTTYATHYTNAARGAR GARCAYTTYGARTCNMGNACNGAYACNATHATHGARTGYATHCARAARGAYATHAARAAY ATHGAYAARATHTTYGAYGCNACNGTNGARGAYTCNGGNTAYGTNYTNACNCAYGGN--- ---ATGMGNATHCCNGTNAGY---GGNACNCAYYTNACNAGYGARGARCCNGARTTYGTN ACNTTYAGYCARGGNATHGAYYTNAGYTCNATHAGYCARGAYACNCCNTTYTGGGAYMGN CAYTTYAARGGNAARAAYGARGTNACNTGGATHGARTTYMGNGAYAARTTYYTNAAYGAY TAYGGNGCNAARATHATHGARGGNTTYTCNGARAAYGGNGARGARMGNAARAARATGTTY GTNAAYYTNATGTAYAARGAYGTNTTYAAYYTNAAYAARGTNGTNAARMGNTCNGTNTAY GAYAARTTYTGYGGNAARCCNCAYCCNCAYGCNTTYTTYACNGGNATGCARGAYTAYGTN ATGGCNTAYTCNTCNYTNMGNGARGTNYTNAGYATGGAYAGYAGYYTNMGNATHTCNACN ATHCARAAYYTNGGNAGYTTYAARTTYCCNGTNATHGTNTCNGCNYTNTCNGAYATGYTN AARGAYGARGAYCCNAAYGTNMGNGCNGTNGCNGCNATHGCNYTNGCNCAYGCNGGNAAR AARGARGARTCNACNGCNGAYAARATHATHGCNYTNYTNGARGAYGARGAYMGNYTNGTN MGNGARAGYGCNTGYYTNAGYYTNGGNTAYYTNMGNTCNACNMGNGCNGTNYTNCAYGTN GTNGAYMGNTGGMGNAAYGAYCCNATHTCNACNGTNMGNGARGCNGCNGARYTNGCNYTN AGYMGNATGGAYGCNCCNGAYGCNGTNCARTGYATGAARGTNACNAARGTNYTNTCNTCN GARATGAAYGCNYTNAARCCN--------------------------------------- ------------------------------------------------------------ ------YTNYTNATHGGNGCNCCNCARGCNCARACNMGNCARCCNAAYGTNGARAARGCN GGNGCNGTNTAYMGNTGYAARACNGAYACNGTNAAYTCNTGYCARCARGTNCCNTTYGAY MGNAAYGGNAAYAAYATHMGNTAYAAYMGNACNYTNAAYAAYTAYYTNCCNATHGARGAR AARTCNAAYCARTGGTTYGGNGCNACNYTNCARAGYTCNGGNGARAGYGGNGTNATHGTN GCNTGYGCNCCNMGNTAYATHTAYTTYGGNYTNGAYYTNAAYAARMGNGARCCNGTNGGN ATGTGYTGGGTNGCNAARACNTCNACNACNGARTAYGARAGYTAYTCNCCNTGYATHGAR GAYATHGARAARATGATHGARAAYTGYGARAARMGNATHGAYGARYTNGARMGNAARGAY MGNYTNGTNAARYTNTCNGAYGARCARTGGCARGAYYTNAARAAYGARAARAARCARYTN GARAARCARATHAARAARTAYMGNAGYGARYTNMGNGGNYTNMGNTGGCARAAYTGGAAR AGYATGGTNATGTCNGTNTGYATHTTYGGNYTNATGTAYGTNGGNTAYATHGTNGTNTTY GAYTCNGAYTCN---------TCNGGNAARAARATGGAYACNTGYGTNCCNAGYCCNAAY YTNYTNAGYGCNCCNTTYGCNGCNAGYCCNGTNCCNYTNTCNATHTAYGARCARGAYMGN CARAAYGTNTAY------TGYGGNAAYTCNAARGTNCAY---TAYAAYYTNGAYGTNTGY GGNGCNATHACNGAYGARAGYGGNGGNYTNGAYGAYCAYTAYGARGAYAGYTCNYTNACN AAYATHYTNACNCCNGARYTNYTNAGYTCNATGGCNTCNTCNTCNTCNTCNTCNTCNGCN CCNGCNTTYACNACNACNGTNCCNAAYYTNTGGAGYACNAARATGACNGCNGARGAYCAY GAYGGNGARCARGCNCCNTTYATHCARTTYGGNGAYGARGCNGAYATG---YTNTTYTCN GARTTYYTNAAYATHGAYTCNAAYGAYAGYAARTTYTCNATHCCNGAYTTYGAYTGY--- ---ATGACNAGYAAYCCNCCNTCNTCNTGYTCNYTNGARTCNMGNTCNGARTTYATHGAR CCNACNGTNGTNGAYMGNATHAGYTTYATGTCNMGN------ACNAARGAYMGNGTNCCN TCNTCNACNTCNTTYYTNGGN---------GGNGAYAGYYTNGCNCARGAYTTYGTNCAR AARAARTTYACNGCNYTNAARTCNAAYTTYCCNCCNMGNAARGCNGARCCNCCNGTNGGN ATHGTNACNCCNGTNAARGAYGARAARGARMGNYTNYTNGAYCCNGTNAAR--------- ------------------------------------------------------------ ---------------------------GTNGARGTNAARGAYCARGCNYTNTGYGCNGTN GAYGCNGCNGARATGTCNCCNCARACNGTNCCNTCNTTYTCNATHACNAAYYTNAAYACN GGNTGYAGYCCNGTNAARATGGARCCNGTNTCNCCNGARTTYACNGARMGNMGNGARTGY YTNAARMGNTCNYTNAAYCARCARTGGGARGAYATGAAYCAYCCNYTNAGYGGNGAYTCN YTNGCNTCNACNAARAARMGNMGNMGNTGYGAYTCNGGNAGYTCNGGNATHACNTCNGAR GAY---GGNGAYTGYGAYGAYGCNTAYGGNTTYCARAAYGAYTAYGAYAGYGAYGAYGAY ---------GAYYTNGAYGCNGAYYTNGCNCAYATGAARCCNGGNAGYTGYGARTCNYTN ATHGGNGGNGGNAARAARCARAARCARTAYTTYTGGCARTAYAAYGTNCARGCNAARGGN CCNAARGGNACNMGNYTNAARYTNGCNGTNGARTCNCCNGCNGAYCCNCAYATHYTNAAY GGNTTYGARGAYCCNGTNTTYGAYGARTGYAAYACNACNGTNGCNGGNATHMGNCAYGGN GGNAARGCNMGNAARGGNGAYGGNAAYGARGTNACNCCNAAYCCNTAYAARYTNTTYAAR ATHGGNCAYCARYTNYTNMGNYTNAAYAARAARATHAAYGCNTGYCARYTNGGNTCNGAY GTNCCNGCNGTNCARMGNAAYGARTCNMGNAARGARAARAAYAARYTNGCNTCNMGNGCN TGYMGNYTNAARAARAARGCNCARCAYGARGCNAAYAARATHAARYTNCAYGGNYTNGAR ATGGARCAYGGNCARATHAAYAAYGTNYTNMGNYTNYTNTGGCCNGARYTNMGNGARMGN GCNAAR------------MGNYTNCARAAYAAYCAYCAYGTNGAYGAYAARCCNGAYCAR GAYAGYYTNTTYAAYAARYTNAAYGGNTAYATHAAYTCNAAYYTNAARAAYATGGTNGCN GGNCAYACNACNGAYTAYGTNAAYGAYGTNATHYTNACNGTNGARAARGGNGAYATGTTY GGNGGNYTNAARYTNMGN---------------AGYMGNAARTCNGGNTCNGCNMGNTAY GGNGAYGGNGAYYTNAAYTGYAGYAAYATHCCNMGNMGNMGNTCNACNGTNATHAGYGTN AGYGAYGARGGNACNGCNGTNGGNMGNGARYTNGARCCNGTNYTNGCNTAYAARGTNGAR ACNGTNGGNMGNTCNGCNMGNGCNTCNMGNATHYTNAAYGARYTNGTNATHGARAARGTN GAYGGNGARAARAGYTTYTTYGARGTNTCNATHGAYGARTCNGTNAARGCNAGYGTNTCN YTNTCNGARTCNAARTCNAAYACNTCNYTNGGNATHAAYYTNAAYAAYACNTCNCCNTTY ACNCCNMGNAARTCNAAYGARGTNACNGCNTCNAGYAAYAGYGCNACNTCNACNCCNYTN TCN------ACNCCNCARTCNGCNYTNMGNACNMGNCAYTCNGTNGCNCCNTCN---TCN GGNTTYAARGARCCNGGNYTNCCNYTNTCNGCNYTNMGNCCNGCNGGNTCNCARMGNMGN AARACNACNTAYACNCCNAARTCNAARACNCCNGARCAYATGATHAAYATHYTNCARAAR AGYCCNATGGTNGARATGAAYMGNMGNAARTCNMGNCAYATGACNTCNCCN------GCN CCNAARGGNCARTTYTTYMGNGAYYTNATHAAYAAYGARACNGARMGNYTNACNAAYYTN TCNAAYMGNTGGAAYCAYATHGCNGARACNGARATGGGNYTNAARGARGARGTNYTNGGN CARATHMGNTCNACNGTNGGNAARGCNYTNYTNYTNATGGAYCARMGNTTYAARCARTTY TCNGGNYTNATHGAYAAYTAYGTNTAYGAYYTNGGNGARAARAARACNACNCCNACNGAY YTNCARGGNTTYTGGGAYATGATHTAYTTYCARGTNGARGAYGTNAAYAAYYTNTTYAAR GAYYTNGARGARYTNMGNCARTCNGGNTGGGARGTNAARGARAARATHCCNAARGTNGAY ACNYTNAGYYTNAARAARAARGTNATHAARAAYAARCCNAARACNAARGGNGTN------ ------AARTCNAAYTTYGCNGCNTTYMGNGCNGARYTNCARAARAARAARGCNGCNCAR GCNTCN------------GARGARYTNAARAARYTNAARGTNCCNGARYTNAARCARGCN YTNAARGAYAARGGNYTNAGYTCNTCNGGNACNAARACNGAYYTNATHAARMGNYTNATH GARTCNGARGTNGCNTCNGGNGAY---TGYGCNGAYCCNGTNATHGAYGAR--------- ------GAYGARATHYTNAARGAYGAYTCNACNCCNGCNGTNCCN--------------- GCNGTNCCNCCNACNTCNCCNCCNGCNTCNCCNGTNAAR--------------------- ------GCNGCNGCNGCNAGYAAYGGNGTNACNACNACNAGYTCNGARCCNAARCCNAAY GTNCARGTNACNACNGAYTCNACNATHGTNGCNAARCCNATHGARGTNAARAARYTNACN GAYGCNGARMGNYTNAARATGMGNGCNGARAARTTYGGNGCNTCNTCNGARCARGCNAAR AARGAYATGMGNGCNCARMGNTTYGGNATHGCNYTNAGYGARAAYAARTCNGGNAAYATH AGYTCNTCNTCNGARCCNGTNGAYGTNGARAARYTNAARAARMGNGCNGARMGNTTYGGN GTN------------TCNACNAGYTCNGTNACNGARGAYGARAARAARMGNAARMGNGCN GARMGNTTYAAYACNAGYYTNACNACNACNACNTCNTCNAARAGYATHAGYYTNAAYTCN ACNGAYAGYGARYTNGARGCNAARAARMGNAARMGNGCNGARMGNTTYGGNYTNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARGTNAARAARGCNGTNGTNTTYTGYGAYAARAARATGGCN CARGTNYTNCAYTGGATHGGNGGNATGGGNGCNYTNYTNGAYGCNGGNGCNCARGAYGTN MGNGARTTYTCNTCNTTYGARAGYGGNGAYGARAAYCARAARAARGGNGTNTTYYTNATH AAYGGNCCNYTNGARGGNGTNACNGARCARGTNYTNCARGAYATHYTNACNCARAGYCAY TTYCARTAYGTNGTNGTNYTNACNACNGCNCAYCCNYTNYTNCAYGCNAAYATHACNGCN GCNAGYATHGARAAYGGNGCNGCNTTYGARGAYTTYGARGARCARYTNYTNGARTGGATG GGNAAYATGAAYTAYACNTCNGARGTNCARCAYGTNAAYYTNTTYAGYTGYGARYTNTGY CCNGGNTTYTTYATHACNCCNGCNTTYTCNGARYTNTTYCCNYTNYTNCCNTCNGAYYTN CARCARATHAAYTAYCARCARGGNGTNMGNAAYGTNAARGAYGCNACNAARAAYTGYGAY AGYYTNAGYGAYGTNGARATHACNAAYYTNCCNGARGAYYTNGARATHCARATHMGNYTN TTYTCNACNTGYYTNGAYGGNYTNYTNCARGCNATGAAYGTNAARGARGARATHTAYTCN ATHGGNAGYYTNAGYMGNATHATHGCNACNGAYYTNGAYAGYTTYCCNCCNGCNAARGCN MGNMGNAARACNAGYCARTCNMGNATGTCNYTNYTNYTNGTNGAYMGNAGYYTNGAYTCN GCNACNGGNGTNACNMGNCARGCNGAYGCNYTNYTNGAYAARATHTTYAAYACNYTNCCN GCNYTNGAYGAYAAYAGYACNGAYMGNYTNATHGAYATGMGNGAYYTNTGYCAYTGYTAY AAYAAYAARTCNAGYAARAGYGTNATHYTNCCNGGNTGYYTNGCNCCNCAYAARGTNCAY GAYTCNCCNGCNCAYYTNACNGCNACNATHATGAARAARCAYAARGARGCNYTNATGGAY ATHAAYMGNMGNYTNGTNGARACNGCNACNTCNGARAARYTNCCNYTNGAYYTNTCNMGN MGNCCNAGYMGNGTNACNGCNGAYYTNYTNGAYTCNACNYTNTCNYTNTTYAARGGNAAR TAYAARYTNATHCARAARCAYYTNGAYTCNYTNCARGTNGCNATHGCNACNAGYCARGCN YTNAARCAYCCNTCNGCNCCNCAYCAYGAYGCNGTNGTNGCNMGNGARAARAAYTTYYTN CARGCNATHGCNGAYTCNGARGGNTGYGARGAYGGNGAR---------------GTNAAY GAYGCNTAYCCNTCNGCNTTYGCNYTNYTNTCNAARYTNATHGCNGARGARYTNMGNAAR GAYGCNGARGARMGNYTNTTYACNGTNGAYGAYTTYYTNCARYTNYTNGTNTAYGTNTAY TCNGTNTCNGAYGGNAGYAGYGARCARCARGAYGARGTNCAYGCNYTNCARGAYCARYTN GTNCARTGYGTNATHAARGAYAARGARTGYYTNCCNCCNATHATHAARGCNATHGTNGGN GAYAARGTNACNGARGCNATHYTNCCNGAYCARATHGARAGYATGTGGGARMGNYTNGAY GCNYTNATGGARGTNMGNMGNGAYYTNAARGARTTYGGNAAYYTNYTNGAYCCNGGNGGN GCNATGAGYCCNGCNTCNGTNAAYCCNYTNYTNAARCARGTNATGGARAARATHYTNGAY CCNGGNMGNCCNGARATGCCNGAYGTNGARTGYAARTCNGGNGGNYTNAARGAYYTNYTN AARTCNGGNTTYGGNTTYTTYAARAGYAGYGCNAARCCNMGNCCNGGNGAYGCNCCNYTN YTNATGATHGTNGTNGTNGGNGGNGTNACNGGNTCNGARGTNAARATHATHAARGAYATG GTNAAYAGYGCNAARCCNGGNTTYGARGTNGTNGTNGGNGGNACNMGNATHAAYAGYACN GARGCNACNYTNAARTCNYTNYTNGTNGAYGAYAAYATHAAYGTNAAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNTCNGAYATGTCNCAY AAYAARGTNCCNMGNGTNGARGTNGARGAYGAYCCNGCNCCNYTNATHMGNTTYYTNTGY GGNGCNGAYYTNYTNGARTCNTTYTCNGTNCCNGGNYTNTGGGCNGAYGAYGAYGTNGAR GCNATHGTNAARAAYTAYGGNYTNGTNGTNATHAAYMGNGARGGNTCNAAYGCNAAYAAR TTYATHTAYGARTCNGAYGTNYTNTCNAARTAYAARGARAAYATHYTNYTNGTNAAYGAR TGGYTNAGYYTNGAYATHAGYTCNACNAARATHMGNMGNGCNTGYMGNMGNGGNGARAGY YTNAARTAYGTNGTNCARGAYGCNGTNATHGAYTAYATHCARGARCAYMGNYTNTAYGGN YTNCCNGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TCN GAYATHACNTAYGTNAGYGCNAARGTNMGNTTYGCNAARMGNTGYYTNCARYTNAARMGN TTYACNGARGCNGCNGARCARTAYTCNGGNYTNGTNAARATGYTNCARCAYGARGAYATH TTYYTNCARTTYGARMGNCAYGARATHAARCARGARYTNAAYATHGCNGARATHYTNGTN GARGCNGCNGARGTNYTNGTNATHACNTGYCARTAYCARGAYTGYATHMGNYTNTGYAAY GAYACNCARCCNTCNATGTCNGTNGAYGAYTCNATGGCNAARACNAAYCARMGNAAYGGN AGYTAY---------------------------------TCNACNAAYATHTCNGTNYTN GAYAAYTCNCARACNGAYATHTTYAAYYTNYTNGARGAYTCNCAYAGYGARGAYAAYTTY CAYCCNTTYTCNTGYTCNGGNAARAARYTNCARTCNTCNATGGGNMGNAGYAAYCCNTCN ACNGAYYTNTCNACNTCN------------------TTYGARAARTCNMGNAARMGNATG MGNTCNGAYGARCCNAAYAGYGARGCNGGNGTN------------GAYAAYGARAAYGAR TAYGARAGYTGYAAYGAYYTNYTNATGGCNMGNYTNCAYYTNTGYAARGCNGAYGCNYTN GCNYTNTCNCAYGGNTTYGCNGAYGARGTNGTNCARTGYYTNCARCARTCNYTNGAYATH YTNATH---MGNCAYCCNTCNTCNACNCCNTAYTGYCCNCCNCAYCARGCNCCNCAYTTY AARMGNCARMGNATHAGYTCNGAYCARAGYACNYTNCCNAGYATGGGNCARCARTCNGAY YTNTCNAARGGNTCNGGNGARAGYGAR---TGGACNMGNYTNYTNGTNAAYACNGCNYTN MGNATGGCNGCNGCNTCNTGGAARMGNAARMGNTTYTCNTCNGTNATHAAYAGYTGYMGN GTNGTNGARCARYTNGAYAGYGGNAAYYTNGAYGCNGCNTAY---------------GGN YTNCARTCNGGNTTYMGNCCNGAYCCNTCNGAYTGYAAYAARTTYTTYCARTGYYTNAAY GGNATGACNYTNAAYGGNCARTGYCCNAGYMGNYTNGTNTTYAAYCCNACNACNTCNGCN TGYGAYTTYTCNYTNAAYGTNCCNGGNTGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TGYGAYGGNAARYTN YTNATHGTNGGNGAYGGNGAYTTYTCNTTYACNGTNTCNYTNGTNAARCAYTGYAAYYTN AAYCCNACNMGNGTNTTYACNTCNAAYYTNGARACNGARGCNTCNATHYTNCAYCAYGCN CARGCNTCNACNAAYATGAGYAGYYTNMGNGAYYTNGGNGTNTGYGTNTTYYTNGARACN GAYGCNACNGAYYTNCAYAAYCAYCCNGTNATHAAYAARAGYAGYTTYGAYMGNATHATH TTYAAYTTYCCNYTNGCNGAYMGNCAYAAYATHAARAARAAYMGNTCNYTNYTNGCNGAY TTYTTYTCNAGYTGYMGNTCNGTNYTNGCNCCNGGNGGNMGNGTNYTNGTNACNYTNTGY AARGGNCARGGNGGNACNCCNGCNGAYCARCCNGTNMGNTCNTGGCAYGAYAGYTGGCAR GTNGTNGCNATGGCNACNAAYGCNAGYTTYYTNYTNTGYGARGTNYTNCCNTTYGAYCCN GCNGARTTYCCNGARTAYCAYAGYGTNGGNTTYMGNTTYCARGAYAARAGYTTYAAYGTN AGYGGNGCNYTNACNCAYGTNTTYGARGARGGNTCNYTNGTNGARGAYTTYGARGGNAGY ACNMGNGGNGTNTTYGARTCNGAYGGNCAYACNTAYTCNTGYAAYAGYTAYGTNGCNTCN CAYYTNAARMGNAAYYTNYTNGARGARGCNMGNAAYCCNGTNTGYATHYTNMGNMGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATHMGNYTNMGNYTNGCNTTYAGYATHACNGGNGTNYTNGTNGGNYTNTCN GCNGGNGCNGTNTTYGGNYTNCAYTTYAARAAYTAYAAYGCNTCNYTNTGGGGNYTNTGY TCNGGNATHGCNGCNTTYGTNGCNYTNTGYGTNACNATHGCNTTYACNAARMGNTCNTGG GAYGCNAAYCCNCAYMGNYTNMGNTAYTTYATGYTNAGYGGNTGYTTYATHCARYTNGCN GGNGTNTGYGGNTTYGTNGCNTAYYTNGTNYTNGCNATHTCNCARCAYCARAARGTNGAY GCNTAYGAYGARGGNTTYTAYGTNGTNTGYGTNTGGTGYTTYATGACNTGGAARTGGGGN TTYYTNYTNYTNATHTAYTCNMGNTCNTAYYTNMGNACNTAYATGAGYGAYTCNGAYCCN TCNTCNTAYTCNGARCCNGARAARTGYGTNATGAARCARYTNACNTGGAAYGTNAARYTN GAYTTYTCNGCNCAYACNATHAAYGGNGTNGCNAGYYTNTAYTTYGARAARAARACNGAY GCNYTNGAYACNYTNYTNYTNGAYATHMGNGAYYTNAARATHGARAGYGTNAARYTNCAY GARAAYAAYCARAAYYTNAGYTTYACNGTNGAYAAYCCNGCNGCNGTNGAYTAYGGNTCN MGNYTNTGYATHCARYTNCCNGTNYTNCARAGYAARAGYTTYACNYTNGAYATHACNTAY AGYACNTCNGARAAYTCNACNGCNYTNTGYTGGATGACNCCNCARCARACNGCNGGNAAY MGNCARCCNTAYYTNTAYAGYCARAGYCARGCNATHCAYGCNMGNAGYYTNTAYCCNTGY CARGAYACNCCNGCNGTNAARTTYACNTAYAARGCNAAYGTNGARGCNCCNAARGARATH ACNGTNYTNATGAGYGCNAAYMGNGGNGARGTNACNCCN------GGNTCNGCNGGNCAY AGYGTNACNAGYTTYTCNYTNGAYGTNCCNATHCCNAGYTAYYTNYTNGCNATHGTNGCN GGNGAYYTNGARTCNMGNGAYATHGGNCCNMGNTCNAARGTNTGGTCNGARAARGARYTN GTNGAYAARGCNGCNTAYGARTTYGCNGARACNGARTCNATGYTNCARGTNGCNGARGAY YTNATGGGNCCNTAYGTNTGGGGNCARTAYGAYYTNYTNGTNYTNCCNCCNTCNTTYCCN TAYGGNGGNATGGARAAYCCNTGYYTNACNTTYGTNACNCCNACNYTNYTNGCNGGNGAY MGNTCNYTNGTNAGYGTNGTNGCNCAYGARATHTCNCAYAGYTGGACNGGNAAYYTNGTN ACNAAYGCNAAYTTYGARCAYTTYTGGYTNAAYGARGGNCAYACNGTNTTYYTNGARMGN AARATHCAYGGNAARYTNCAYGGNGARGCN---TGGAARCARYTNCAYGCNAAYGARGGN TGGACNGGNYTNAARGARACNATHGAYGTNYTNACNGARGAYGGNCARGCNCCNTAYACN MGNYTNGTNCCNGAYYTNTGYGGNGTNGAYCCNGAYGARGCNTTYTCNAARGTNCCNTAY GARAARGGNTAYGCNYTNYTNCARCAYYTNGARACNYTNYTNGGNGGNCCNGAYGTNTTY AAYGTNTTYYTNMGNGCNTAYATHGARCAYTTYAARTAYCARTCNATHYTNACNAARGAY TGGAARGAYTTYYTNTTYGGNTAYTTYTCNTCNGCNGARGAYCARACNAARYTNGCNAGY ATHGAYTGGGAYAARTGGYTNTAYGGNGARGGNGTNCCNCCNTTYGARCCNGAYTAYGAY YTNAGYYTNGCNAARGCNAGYGARGAYYTNAGYAARMGNTGGYTNGAYAGYGCNGARAGY AAR---GAYGTNTTYTCNCCNYTNGAYATHAARGAYATGCCNAGYGAYGTNGTNMGNGAY TTYYTNGCNAGYYTNYTNCARGCNCARCCNTCNYTNCCNAARGCNAARGTNGARMGNYTN GARTCNGTNTAYCARTTYAAYGCNGTNAARAAYTCNGARATHMGNYTNAARTGGYTNCAR YTNTGYATHCARGCNMGNTGGACNGARGCNATHCCNTAYGTNYTNGAYTTYGTNAAYGAR CARGGNMGNATGAARTTYGTNATHCCNATHTAYMGNTCNATGAAYAARTGGGAYGARGGN MGNAARCARGCNYTNGARAAYTTYACNAARCAYAARGCNGARATGCAYAGYACNACNGCN AARAARGTNGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNATGGAYAAYCAYGAR GARATHYTNGAYGCNYTNACNGCNTTYGGNAARAAYCCNAAYYTNCARGARATHCCNTCN GTNYTNGARCARTAYYTNAAYTGYGTNGCNAARAAYGGNGARACNYTNTTYCCNTGGTCN CARYTNAARCCNYTNATHYTNMGNAARATGGARYTNGTNATHATGGAYYTNMGNMGNAAY YTNGCNTCNGARAAYATHCCNCCNMGNCCNAAYGTNGARAAYGTNMGNTTYGAYGTNATH CAYGCNMGNATHATHGAYTCNYTNCAYAARTTYAAYGGNGCNCCNTTYACNATHCARMGN YTNTGYGARYTNYTNATGGAYCCNAARMGNCAYTAYAARMGNAGYGAYAARTTYATGMGN GGNYTNGARAARAAYGTNYTNGTNGTNAGYACNGTNGAYCCNTTYGGNMGNAARGTNGTN TCNGARYTNGGNAAYAARCCNGTNYTNAAYGGN---ATHYTNGAYATH------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNAGYATHCCNYTNATHGCN YTNCCNAARGCNTCNACNCCNACNYTNACNCCNCCNCCNAAYTCNMGNACNCCNACNCCN ACNYTNGCNGGNTCNMGNMGNTCNTCNAAYGAYYTNTCNCARCARATHGCNGCNGGNGGN AAYCARCARCARACNYTNCARCARCARAAYYTNACNAGYTTYATHCARGGNYTNACNTCN GGNACNGTNGTNGCNGGNGCNGARAAYCARAGYTCNGGNCARCARCAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TAYMGNTTYTAYCAYTGGCAYYTNATHGAYACN TTYGTNTAYTTYAGYCAYMGNTTYATHACNATHCCNCCNGCNAGYTGGATHCARGCNGCN CAYAAYAAYGAYGTNCARATHYTNGGNACNYTNATHACNGARTGGGARGAYGGNTCNAAR YTNTGYMGNGARYTNYTNAARTCNMGNGAYAAYATHGAYYTNGTNGCNMGNAARYTNGCN GAYATHGCNATHGCNTAYGAYTTYGAYGGNTGGYTNATHAAYATHGARAAYTCNATHCAY TGYCAYAGYMGNYTNCARGCNGCNAARGTNYTNTGGTAYGAYAGYGTNACNAGYGCNGGN GCNYTNGAYTGGCARAAYGARYTNAAYGAYAARAAYCARYTNTTYTTYACNGTNTGYGAY GGNATHTTYYTNAAYTAYACNATHACNGARGARAARYTNGCNCARTCNMGNCARGTNGCN CARGCNGCNGAYMGNTGYTTYGAYGTNTAYGTNGGNGTNGAYGTNTTYGGNMGNGCNCCN CCNGGNTGGGGNGGNTTYGAYTGYAAYAARGTNYTNGARYTNATHTCNAARCAYGGNYTN TCNTGYGCNATHTTYGCNCARGGNTGGGTNTAYGARGARYTNGGNTGYGAYAAYTTYGAY MGNAAYGARYTNAARTTYTGGAARYTNYTNAARGAYTTYYTNCCNMGNMGNGCNCAYACN GCNCCNGTNAAYACNTCNTTYTGYCARGGNTTYGGNCARAARCAYTAYGTNGARGGNAAR GTNGTNTGYGARAARCCNTGGCAYAAYYTNTCNYTNCARCARYTNCARCCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNACNTCN TCNTCN------------ACNTCNTCNCCNGGNCCN---------CARAARMGNMGNAGY CCNGARTCNGARGARGARYTNMGNCARGCNATGAARMGNYTNMGNMGNYTNGAYGARGAY MGNATGAARATGCARGTNYTNGTNTCNAAYTTYTCNGARGARCARYTNAAYMGNTAYGAR ATGTAYMGNMGNGCNACNTTYCCNMGNGCNTCNATHAARMGNYTNATGCARAAYATHACN GGNGGNACNGTNTCNCARAAYGTNGTNATHGCNATGTCNGGNATHGCNAARGTNTTYGTN GGNGARGTNYTNGARACNGCNYTNGAYGTNAGYGARAARTGGGGNGAYTCNGGNCCNYTN CAYCCNAARCAYYTNMGNGARGCNGTNMGNYTNYTNCAYTCNAARGGNATGATGCCNTCN ACNAARAGYAARAARTCNYTNTTYACNACNATGTCNGCNAGYAAYAARATHAGYGTNCCN AGYGAYAAYAARYTNGGNGCNGTNCCNGCNATGATGAGYGGNGAYCCNGCNACNATGAAR AARGGNYTNATHGTNYTNCARGARTGGTGGGGNATGAAYGARCARATHATGGAYTGYGGN AARGAYYTNTGY---GGNCARGGNAARATGGTNACNYTNGTNCCNGAYYTNTAYMGNGGN AARGTNACNAARGAYAAYGARGARGCNGGNCAYTTYATGGGNGAYYTNGAYTGGCARGGN GCNGTNGCNGAYATHCARGCNTGYGCNMGNTAYYTNAARAGYAARGGNGTNAARAARGTN GGNGTNACNGGNTTYTGYATGGGNGGNGCNYTNTCNATGGCNGGNGCNGCNYTNGTNCCN GARATHGAYGCNGCNGTNCCNTTYTAYGGNATHCCNGGNGCNTCNYTNTGYGAYGTNACN ACNATHAARATHCCNATGCARTGYCAYTTYGCNYTNCAYGAYGCNACNGCNGGNTTYGCN TCNCCNGCNGARTGGCARCCNYTNAARGARAARYTNCARGGNAARYTNAARGAYYTNGAR TTYTAYGARTAYGAYGCNGGNCAYGCNTTYACNAAYTGYACNGGNGAYAAYTAYAARAAR GAYYTNTGYGAYATHGCNTTYTCNMGNATGTTYAARTTYYTNGAYAARCAYYTNTCN--- ------------------------------------------------------------ ---------------------AARGAYCCNYTNGTNGGNACNTGGGGNMGNYTNAARGAY GTNAAYTCNTCNCAYGCNYTNGAYTAYGGNTGGAGYAGYTCNCAYTGYTGYCARGARATH TTYAGYACNYTNMGNATHGAYACNAARAAYGTNYTNTTYAGYCARAARAARCARGCNGTN CCNTTYTAYGCNTCNGGNYTNGGNATHYTNGARCCNACNMGNGGNGGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGGCNGAYTGGCCNTCNYTNGCNATHCCNYTNAGYMGNGTNTCNACN AGYAAYYTNAGYCAYGTNTGYCAYYTNATHGCNGARAGYTTYTGYCARGAYAARCCNATH AARTCNGARAARTTYATHTCNTCNTGGTCNATHGARGARTGGTGGGAYGTNMGNGCNGCN YTNATHGCNYTNATGAARAARGTNGTNCAYCARGAYTGGACNAARGARCARATHCAYCAR GARYTNAGYGCNGTNGAYGAYGCNTAYAARGCNGTNATHTCNGARGCNATHTCNATHCAR MGNGTNTCNYTNAAYMGNAARYTNYTNCARAAYACNGCNTCNGTNTCNCAYGCNATGYTN TCNGAYTTYGAYTGGAARYTNCARYTNGCNYTNTCNAGYGAYAARATGTCNAGYYTNCAY CARCCNTTYGTNACNYTNGAYYTNGAYATHMGNCARTCNAAYGGNACNMGNAARGARGTN GCNYTNGARATGGGNAARGARGARYTNACNAARYTNATHTCNTCNYTNGARAGYTGYAGY AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AAYTTYTCNGARGTNYTNGGNAARYTNGGNCARAAY GCNAARATGGTNATHYTNCARTAYTCNCARGCNTTYAAYGCNAGYGARGTNTAYGARCAR CARAGYGTNCARGCNGTNGCNGARYTNGGNGCNCAYGCNGCNATHYTNGARCARMGNYTN AARYTNCARAARGARYTNYTNTGYAAYMGNYTNCARYTNATHACNAAYACNYTN------ ------------GGNCAYGGNGGNCAYCAYGARGGNAARCCNYTNGARTTYTCNTCNGAR ATHCAYAAYAARGAYCAYATHATHGARCAYYTNCARMGNCARATHTCNACNAARCCNAAR GAYCARATGACNGAYGARGARYTNGARTTYCAYTAYTTYAARYTNCAYGAYTAYGAYAAY AAYAAYAARYTNGAYGGNGTNGARATHGGNAARGCNYTNACNCAYTTYCAYGAYGCNGCN GAYGARTCNGGNGAY------------AAYATHAAYAARGARCCNCCNAARGTNTTYAGY GAYGARGARATHTCNAAYATHGTNGAYTCNGTNATHGARGARAAYGAYAGYAAYACNGAY GGNTAYATHGARTAYTTYGARTTYAARAARAARCARGCNGARATGAAR------------ ------------------------------ATGGGNMGNGGNMGNTCNAGYGAYTCNGAY GAYTCNTAYTCNMGNTCNTCNMGNAARAARAARAARGARMGNMGNMGNMGNTCNMGNTCN AAYAGYTCNGGNGARTCNGGNMGNTAYMGNAGYTCNAAR---AARTCNAARAARAGYAAR CAYTCNAGYTCNAGYMGNMGNCCNTCNGAYAGYCCNGARAGYMGNCAYMGNGGNGGN--- ------------AGYGAYTAYTAYAGYAGYAARGARTAYTCNAGYTCNMGN---MGNTCN MGNTCNMGNTCNACNGAYMGNMGNTCNTCNMGNMGNTCNMGNTCNCCNGARGTNAARMGN TCNTAYMGNTCNMGNTCNCCNGARGTNAARMGNTCNTAYAAYMGNTCNMGNTCNTCNCCN TCNTAYTCNTCNMGNGAYMGNMGNMGNTCNMGNTCNAAYTCNMGNACN---AGYMGNMGN MGNTCNMGNTCNMGNTCNMGNAGYTAYAAYAAYCARAGYAGYMGNMGNTCNMGNTCNGGN TCNMGNGGNCAYGGNAGYMGNMGNMGNTCNMGNAGYGAYCARACNCAYGGNGGNGCNTCN TCNGARAARAAYGAYATGMGNATGMGNCARGCNYTNCARGCNGCNGCNGCNGCNGAYGAR AARYTNAARAARGCNYTNMGNGAYCARGGNATHGCNACNTCNTCNTCNCCNYTNMGNTCN TCNATGGCNGARYTNTCNYTNGCNATGACNGCNTCNAARGAYTTYGCNGAYTCNGTNGCN GCNATHGARTCNGGNMGNTTYGTNCARTCNTCNTTYAARTCNGGNGGNATHGTNGTNCAR ACNGAY---CCNGCNCCN---YTNATGTCNAGYCAYGAYGAYGCNATHTTYGGNTCNYTN TCNACNGCNGGNTTYACNATHAARCCNGAYYTNGAYAAYAARCCNGTNGCNATGGAYGCN GAYTCNATHATGCAYCCNTCNYTNTAYTGYAAYGCNGARAARAARATGGARAARTGGATH GAYMGNYTNTCNYTNYTNMGNMGNMGNAARYTNGARGGNGARGCNATG------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNGGNGCNMGNGTNGCNATGGTNGGNAARYTNGGNGAYGAYACN TTYGGNAARGARTAYGARGARAAYATGCAYACNAAYAAYGTNAAYTGYGAYCAYYTNAAR ATHGTNCCNGGNGTNTCNAAYGGNGTNGCNTCNATHCARGTNGCNGAYAAYGGNGCNAAY TGYATHGTNATHGTNCCNGGNGCNAAYAGYCAYYTNACNGTNGARGAYGTNGARAARGCN GARGARACNATHAARAAYTGYCAYGTNYTNATHTGYCARAAYGARATHCCNCARAAYATH TCNYTNGTNGCNATHAARATHGCNAARAARCAYAGYGTNCARGTNATHTAYAAYCCNGCN CCNGCNTCNGCNTCNYTNYTNCCNGARYTNTTYTCNYTNCCNGAYTAYTTYTGYCCNAAY GARACNGARGCNGARATHYTNATHGGNAARCCNATHAARAGYGTNGARGAYGCNTTYGAR GCNTGYAARATHYTNCARGAYATHAARGGNTGYCARMGNGTNGTNATGACNYTNGGNGAR AARGGNGCNGTNTTYAARGAYGTNTCNACNCARCARCCNGTNCAYGTNGCNACNACNCCN GTNAARGCNGTNGAYACNACNATGTCNTTYCCNGGNMGNACNCCNATGGCNATGCCNGGN GGNATGCCNGGNATGCCNCCNMGNATGATGGCNACNCCNGGNTAYGCNTTYACNGCNTCN GGNATGACNMGNATGAAYCCNATGATGCCNATGCARATGGGNATGATGACNCCNATGATG CARCCNATGATG---CARCCNCARATGCARATGCARACN---CARCARCAYATGAARCAR AAYCCNAARTTYGTNCCNCARGARATHCCNAARAGYGAYCCNAARGGNGARAARCCNCCN GTNACNACNGTNTTYGTNGGNAAYATHAGYGARMGNGCNCCNGAYATGATGATHAARCAR ATGYTNCARMGNTGYGGNAAYGTNYTNAGYTGGAARMGNGTNCARGGNGCNTCNGGNAAR YTNCARGCNTTYGGNTTYTGYGARTAYGARGAYCCNGARGCNACNYTNMGNTGYATHMGN YTNYTNAAYGAYTGGMGNATHTCNACNAARAGYYTNGTNGTNAARGTNGAYGCNAARACN AARACNYTNYTNGAYGAYTAYMGNAARAARAARCARGGNAGYGARAGYGARGGNAARAAR GARCARGARACNGGNGARAARCARGARAARAARGARGARGARAAYGGNGAYGAYAARAAR TCNGAYGTNGARGARGARAARGARGARAARGAR------CCN---GARYTNGAYGARAAY ACNCARMGNGARGAYMGNYTNGCNCARGCNGGNYTNGARGCNATHATGAARGARTAYGCN TTYGARYTNAAYAARGARCCNGCNAARACNACNGAYGGNGGNGAYCCNGAYAARGARAAR CARGTNACNAARAARGAYAARGAYATGTAYATGCAYGCNAARGAYACNGGNTTYGAYGAY ATGGARATGGARGAYGARAARMGNGARATHATHAAYMGNGARATHAAYAARTTYMGNGAY NNNNNNNNNGAYGAYGAYGARGARAARGARAARGAYAAYMGNGARAARGARMGNAGYYTN GCNMGNGARMGNGAYMGNMGNCARGARGARAARMGNCARMGNGARMGNYTNGAYAARYTN MGNGARCARMGNGAR---------------CARMGNGARMGNGARMGNGARMGNCCNCCN GCNMGNGTNTCNMGNTCNAARTCNMGNTCNGCNTCNCCNGTNCCNTCNMGNTCNMGNMGN MGNTCNMGNTCN------------MGNGARMGNACNAGYMGNGAYMGNTCNMGNGARMGN MGNAARGARMGNGARATHGARGARGARGARGARATGTAYGARMGNMGNAARYTNGARAAR AARYTNMGNGARAARGARGCNGCNTAYCARGARMGNYTNAARAAYTGGGARGGNMGNGAR MGNAARAARACNMGNGARTAYGARAARGARACNGAYMGNGARGAYGARMGNAARGTNGAR GARGGNMGNGARGCNMGNMGNYTNAARGARTTYYTNGARGAYTAYGAYGAYYTNMGNGAY GAYCCNAARTTYTAYAARGGNAGYGCNYTNCARMGNMGNCARAARGARMGNGARAARGAR AARGARYTNGAYAAYMGNGAYMGNCARMGNGARAARGARGARTTYGARGARATHAARMGN AARYTNTTYGAYGARGGNCAYCCNGAYGCNGARACNGARGTNGCNMGNATGGARMGNGAR MGNGARGARCAYYTNCARCCNMGNYTNCAYYTNCARGARYTNAARCARCCNCCNCARCCN GTNGTNAAYGARGARTCNGAYTCNGAYAAYGARCCNCCNCCNTCN---------MGNACN GARACNMGNCARCCNCCNTCNCCNAARCARCCNGAYCAYCAYCARTCNMGNAAYGGNAAY CARGGNCARCARCARCAYYTNATGCCNGAY------CAYCAYAAYCAYCAYCARCARMGN CCNTCNCCNTCNYTNTCNACNTCNCCNATHTCNACNGAYTCNMGNGTNAGYAGYNNNNNN NNNYTNTGYATGGAYGARTCNTCNCARTCNTCNTTYCCNCCNACNATGCCNCCNTCNATG TCNTCNTCNTCNTAYGGNGARTCNMGNYTNGGNAAYMGNCAYTCNACNTCNTCNACNTCN TTYAAYAAYATHGCNCCNGGNATHAGYCCNGAYTCNTCNAGYYTNCCNGGNGTNACNAAY ATHGTNGAYGGNAARMGNAARAARYTNACNGTNGGNGAYGTNTTYAAYCARGAYGAYGAY GAYAGYAAYGARCCNAARAARMGNAARYTNATHCCNYTNGAYTAYGAYGAYGARAARTCN ACNCCNACNGARAARAARGGNGCNACNGCNGARGARAARMGNCARAARATHAARCARYTN ATHGARAAYATHCCNACNGCNAARGAYGARYTNTAYGCNTAYACNGTNGAYTGGGAYATH GTNGAYCARGGNYTNATGGAYAARMGNATHAARCCNTGGGTNACNAARAARATHGTNGAR TAYATHGGNGARGARGARCCNACNYTNACNGARTTYATHTGYCARAARGTNATHGCNMGN AGYACNCCNCARAGYATHCARAAYGAYGTNGCNATGATHYTNGAYGARGARGCNGARGTN TTYGTNGTNAARATGTGGMGNYTNYTNGTNTAYGARACNGARGCNAARAARATGGGNYTN GTNAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CAYAGYTCNAGYAGYAGYAAYGCNCAYACN AARGCNAGYTCNYTNGAYATGGARTGGGARCAYGARGCNGGNATGTCNCCNAAYAARMGN CCNCARCCNGTNTCNGTNTCNGARGAYAAYTGGTCNAARACNTCNACNGCNAGYCCNYTN CAYTCNAGYGAYYTNGARTGGGAYCCNGAYTTYGTNTCNGCNGARGAYAAYGARMGNYTN GARYTNYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNTTYAARAARAGYGTN AARTAYTAYGTNAGYGGNACNCARGARGGNTAYTTYAARTAYGTNYTNAAYMGNGGNCCN YTNATGTCNCARCCNATGTAYGGNGGNGGNCAYCAYCCNYTNYTNGGNTAYGAYGAYCAY AARCAYAARGGNAAYGCNATGGGNGAYGCNAGYACNGTNMGNAGYGCNGGNYTNCCNCCN GTNTCNAAYGARATHATGMGNGTNGCNATHGAYMGNCAYCARAARGGNYTNATGCAYCCN YTNATHTAYCARGTNYTNACNCARGGNGARGTNAARYTNCCNGTNATHYTNGARGAYGAR ACNCCNMGNGAYYTNCCNAGYTAYATHGAYTGYTAYMGNCCNATHMGNGARACNATHTAY TCNGTNYTNYTNAAYYTNAAYAARCARAARATHGTNCAYGARATHCAYAAYAARGARAAR TCNAAYAARGCNTCNTCNGAYTTYACNGCNCARGTNAARGARTGGGTNGTNMGNMGNGGN TCNGGNMGNGCNGCNTAYGARGTNGTNACNGCNMGNCCNGTNGARTGGAARACNCCNAGY GTNCARMGNATGTGGYTNGGNCARCARGAYGGNGAYAARGAYMGNMGNYTNMGNGCNTTY YTNACNATHATGATGTCNGAYTCNAGYYTNATGYTNAAYACNAAYTAYATHCCNTCNCAY YTNYTNGTNATGTGYTGYGTNYTNMGNTAYATGYTNCARTAYGGNMGNATHYTNCARMGN GCNGARYTNGAYGCNTTYYTNGCNATGTCNGTNTCNCCNYTNYTNAGYGAYATHCARACN ATGCARGAYYTNAARYTNCCNCARATHATGCCNMGNGGNAGYCARYTNGCNTCNYTNTTY ATGGCNGGNATHGARACNGCNTGYATGGCNAAYGAYGTNTGYGGNGCNCCNATHCCNTGG ACNATGATHTGYCCNTGGYTNTAYATGGAYGGNAARYTNTTYCAYTAYAARYTNYTNAAR GCNAAYAAYAAYACNCCNYTNATHGAYGTNTGYGAYGGNCARATGGARCARGTNYTNMGN GTNGARMGNATGMGNCARGCNATHYTNGARAAYYTNCAYGTNGAYTTYGCNMGNCCNYTN ATGGCNGGNTAYYTNTAYCCNTAYCCNGGNCARCCNATGGGNCCNGGNCAYATGCCNTAY CCNCCNGCNGGNTCNGGNATGACNMGNGGNGGNCAYCCNGGNMGNCARCCNGGNMGNGGN GGNMGNTCNCCNGTNGARGCNMGNGGNGGNCARYTNGARATHGCNGGNGTNGTNGTNGGN CARTGGGGNCCNAAYATGTCNGGNMGNMGNGGNMGNGGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------ATGGCNGAYGAYTCNGAYATHCCNCCNYTNGARGAYATGACNGAYGTNYTNCAR AARGCNGARYTNATHMGNGARYTNMGNTTYGGNTCNAGYTCNCARGTNACNTCNAARTCN CARATHGARGAYGCNAARAARMGNGCNAARGTNACNAARAARACNCCNACNGAYACNTCN ACNAAR------------AARACNTCNGAYACNAARGARAARACNGARAAYGARAARCAR GARAAR------------------------------------------------AARGTN GAYAAYGTNAARTCNGCNAGYTCNGGNGGNCARGGNYTNTTYGGNGGNATGAARAARGGN TTYYTNTTYGGNGGN------------CCNAGYAARCARTCNTCNACNAAYGCNAARACN AAYGTNAARCARACNCARAGYCARCCNTCNAGYGAR------------AARAARAGYATH TCNTCNAAYGCNTCNCCNAARGARGAYATHCCNTAYATHACNCCNAARGGNAARAARGAR TCNGGNYTNAGYTTYAAYGARGTNCARCARGCNATGTCNGARGCNAARGGNYTNYTNGAY AAYCARGARTGGATHACNGAYGAYTTYYTNAGYAARATHGARAARAAYGAYACNYTNYTN AARMGNTTYAGYGAYCCNAARTTYATGGCNGCNYTNCARGARTTYCARACNAAYCCNCAR GCNGCNATHGARAARTAYAARGGNAAYCARGAYGTNGARCARTTYYTNATGGARTTYTGY GGNYTNYTNGGNGAYCAYTTYACNAARYTNGGNAGYAGYGGNGARAAYTCNCARGCNACN CAR------AARAAYAGYGCNAARTCN--------------------------------- CCNCARCCNGGNGTNAAYCCNAARMGNAAYAAYGARCARCCNYTNCARTCNACNACNCCN AARATHGTNGARATHGGNGAYGAYGGNGGNGGNATHAGYAAR------------------ ---------------------------------ACNGTNAARAAYCCNCCNGCNAARCCN AAYAARGCNAGYGTN---------------------AARACNGARTCNCCNGAYATHMGN ATHCAYGAYTCNCARAAYGCNGCNGAYATHCARGARATHCCNCAYCARCARGARGTNCAR ACNGAYGAYGCNGCNGTNMGNGARGTNYTNAAYGAYCCNAARGTNATGGARACNYTNATG GAYCCNAARGTNATGGCNYTNATHAARACNYTNMGNGARGAYCCNGARAARGGNCARMGN ATHATHGAYAARGCNGAYYTNGAYYTNAARGARAARGTNMGNTTYYTNGTNGAYMGNGGN YTNYTNCARTTYCAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------TGYGGNGTNGCNTGYTTYGTNMGNGAYAGYTCNAARMGNTCNTTYTTYATHAAR GTNTTYGAYATHAARAARCARCARATGYTNTGGGARCARGARYTNTAYAAYCARTTYGTN TAYAARACNCCNMGNGARTAYTTYCAYACNTTYGARGCNCAYAAYTGYCARGCNGGNYTN AAYTTYGCNGAYGARGAYGARGCNGTNAARTTYAARAARGCNGTNGAYGGNAARYTNAAY GARMGNAARCARAARAARATGGARMGNMGNCARAARTCNGTNTCNAAYAARCAYAAY--- ------GCNAGYCCNGGNCARGGNTCNAGYGCN---CCNCARMGNATGGGNGGNGTNAGY AAYGCNGCNCCNGCNCCNGCNGTNCAYGTNGAYGTNAGYMGNCCNAAY------ACNAAY AAYACNAARAARGAYAARCARGAYAARAARAARGAY---GGNAARAARAARYTNACNAAR GCNGAYATHGGNACNCCNTCNAAYTTYGTNCAYGTNAGYCAYGTNGGNTGGGAYCCNGAY AARGGNTTYGAYATGAAYAAYYTNGARCCNGAYATGCARACNYTNTTYCARTCNGTNGGN ATHAARCCNGARGAYMGNGTNGAYAARGARACNGTNGAYTTYATHTAYGAYTTYGTNGAR AARCARGGNGGNATGGARGCNTTYAGYAARGARYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGGCNTCNYTNTTYGGNGAYCAYMGNYTNYTNACNAARAARGTN TTYGAYGARATHTAYATHCAYGARAARGAYMGNGAYAAYTAYAAYACNGTNCARGCNAGY GARGCNYTNGARGGNAARGTNGTNTGYYTNTTYTTYTCNGCNTCNTGGTGYACNCCNTGY CARCAYTTYGTNCCNACNYTNAARGARGTNTAYACNGARYTNGTNCAYMGNAAYAGYCCN YTNGARGTNGTNTTYYTNAAYTTYGAYAARACNGARGARGARATGATGAGYTAYTAYCAR GARAARCAYGGNGAYTGGYTNGCNGTNAARTTYGGNGAYTCNYTNAARCARGARYTNGCN GARMGNTAYTCNATHMGNGTNATHCCNMGNYTNATHGTNGTNCARCCNGAYGGNGARGTN ATHAGYGCNAARGGNMGNAARGAYGTNCARGAYMGNGGNGTNGTNTGYATGMGNACNTGG CARGCNGGNTAYGAYMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYGTNTCNAGYATGMGNAARCCNTAYMGNGAYAAR YTNGAYATHTTYGAYGTNAARGAYYTNTCNTCNAARGAYCCNTTYGARCARTTYTCNGCN TGGTTYGARGARGCNAARTCNACNCCNGGNATHTTYGARGCNAAYGCNATGGCNYTNGCN ACNGCNTCNMGNGAYGGNAARCCNTCNGTNMGNATGGTNYTNATGAARGGNYTNAGYAAR GARGGNATHGAYTTYTAYACNAAYTAYCAYAGYMGNAARGCNCAYGAYYTNATHGARAAY CCNGTNGCNAGYYTNATGTTYTAYTGGGARACNYTNAAYAARTCNGTNMGNATHGARGGN ACNGTNGCNAARYTNTCNGTNGARCARTCNGARCARTAYTTYCAYTCNMGNCCNMGNTCN AGYCARATHGGNGCNTGYGTNAGY---CARAARCARAGYTCNGCNATHCCNTCNMGNGAR GTNYTNGAYAARMGNAARGARGAYYTNGARTCNGARTAYAGYGAYGARAAYGTNGTNATH CCNAARCCNGAYTAYTGGGGNGGNTTYMGNYTNGTNCCNGARCARTAYGARTTYTGGCAR GGNCARTCNAAYMGNATHCAYGAYMGNATHGTNTTYMGNAARCCNGGNGCNGARGARGCN ATHGAYACNTCNGTNACNTTYCARGCNAGYGAYGGNTGGGTNTAYGARMGNYTNCARCCN CARTCNCAYATHGARAARATGCCNTCNATGATGGGNMGNCARGCNMGNYTNCARTTYCAR TCNMGNYTNACNGGNTTYGARGAYGCNYTNGARAAYGCNYTNAARGCNGCNAGYGARCAR CARTGYATHATGTCNGAYGARGTNGTNTCNTAYTCNATHATHTCNGTNACNAARGAYGTN CARCAYACNAGYAAYCCNTGYTTYAAYACNCAYCAYAARTGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GCNAARCCNYTNAAY GAYCCNTTYAARTCNTTYGTNGARAAYTCNAARAAYGGNATHATHYTNGTNTCNTTYGGN AGYACNYTNGCNCAYATHCCNCCNTAYATHTTYCAYAARATHAAYGCNGCNTGYAARGAY ACNAARATGAAYATHATHTGGMGNTCNGAYGARCCNTCNYTNGAYTCNAARCAYATHYTN ACNAAYAAYTGGATHCCNCARAAYGAYATHYTNGGNCAYAARAAYACNAARYTNTTYATH TCNCAYTGYGGNAARAAYGGNCARTAYGARTCNYTNTAYCAYGCNGTNCCNATHYTNTGY YTNCCNATHTTYGGNGAYAARCCNTAYAAYGCNGARMGNGTNMGNACNAARGGNYTNGGN YTNAARGCNGAYATGMGNTTYGTNTCNGTNGARGAYYTNTCNAGYATGGTNMGNGAYYTN GTNAGYAAYGCNACNTAYAARGARAAYATGAARAARGCNTCNAARYTNTTYMGNGTNYTN TAYAARTCNCCNATGMGNGARGCNGCNTTYTGGYTNGAYCAYGTNYTNCARTTYGGNGGN GGNTAYATGMGNGCNGCNAGYCARACNATGCCNTAYTAYCARTTYYTNYTNATGGAYGTN TTYGCNTTYYTNTTYYTN------------------------------------------ ------------------------------------------------------------ ---------------------------------AAYTCNTTYTCNYTNATHAARTCNACN GCNTTYGTNACNGGNGTNTGYGGNTGYAGYTTYYTNGGNGCNATGATHTGGAAYTAYGAR AAYGTNMGNCARGTNTAYAARGAYATGGCNGCNGARAARGCNCAYAGYATGACNAGYMGN ATGAAR---------AARGCNTTYGGNTTYMGNCARCAYATGAAYGAYATHTGGGARAAY GTNGAYTCNTCNACNAARYTNACNATHGGNATHATHGCNGCNAAYGTNGTNGTNTGGGGN YTNTGGMGNGTNCCNMGNTTYCARTCNTCNATGATHMGNTAYTTYTCNTCNGCNGCNGCN CAYCCNAARTCNTCNATGGTNYTNAGYAGYTTYAGYCAYATHAGYATHATHCAYYTNTTY GTNAAYATGTAYGTNYTNYTNTCNTTYGCNCCNGTNATHACNMGNACNTTYGGNMGNGAR CARTTYTCNGCNTTYTAYATHAGYGCNGGNACNATGTCNGCNTTYGCNAGYATHYTNTGY CARAARYTNYTNAARMGNCCNYTNGCNGTNTCNGTNGGNGCNTCNGGNGCNATHATGGGN YTNYTNGGNATHACNGGNYTNYTNTAYCCNAAYGCNCARYTNCARGTNGCNTTYGTNTCN GARATHATHCCNCAYTCNTTYTCNGCNGARACNGGNATHAARGCNATHATHYTNTTYGAY YTNGTNGGNYTNTTYATGGGNTGGAARGTNYTNGAYCAYGCNGGNCAYYTNGGNGGNATG YTNTTYGGNYTNTGGTAYGCNAARTTYGGNAAYAARYTNATHTGGGGNAAYMGNGAYCCN GTNGTNMGNGCNTGGCAYGAYYTNMGNGGNAARCCNAARACNTCNGARGARATGGARYTN GARAARATHGARGARATGMGNAARCARTTYGCNAARTCNAARAARAAYCAYGARATHGTN TAYAARAARGCNATHGCNCCNGGNAARCCNATGGCNYTNAARTCNAGYCARCCNCCNACN ATHCCNCARGGNTTYMGNTTYCAYTCNGAYYTNMGNATHAARGGNACNGCNGARGTNTCN GARGAYACNTCNGTNAARGAYTTYACNAARATGYTNMGNTCNACNGGNGCNAARTCNCAR GGNCCNAARMGNATGYTNACNAARCCNCARCCNTTYAAYYTNACNAARAGYACNTCNAGY YTNCARGCNGARAARTAYATGTCNACNGCNGARCARGTNGTNGCNTAYAAYGCNGGNYTN MGNAGYGGNGCNGGNGGNCCNTCNTGYTCNACNAGYGGNMGNCCNGGNTCNCCNACNYTN ACNATHGCNAARACNCCNAAYYTNAGYACNMGNGGNMGNTCNMGNTCNGTNAARATGYTN ACNMGNGARGARGARGARGARGCNGARTTYGARAARCAYMGNCARCARCARTTYAARGCN CAYGGNGTNAAYCAYAARATHTTYACNGARCCNCARYTNGGNGTNMGNAARATHCCNGCN AARCCNCCNACNMGNGTNCARGARTTYAAYYTNCAY------ATGGCNACNTCNCAYCAY GTNAARGCNTCNAARGAYTCNGAYGARAARACNATHGCNTTYCAYGCNCAYCCNGTNAAY CARAARGTNYTNGAYGGNCCNACNGGNATHAARCCNGCNGAYAARMGNCCNYTNACNGTN GCNCARTCNCCNGCNTTYTCNYTNAARAAYMGNYTNMGNGARMGNYTNCARCCNCCNAAR GTNGARCCNTGYCCNGARCCNCARAARTCNAARCCNGTNCCNCAYATGGGNGTNCCNTTY MGNCCNCARYTNGARCAYAARCAYACNGTNACNAARCCNTTYGCNGTNGARCARCAYAGY AARGAYATGYTNAARAARAARGARYTNAARATHCARCARGTNYTNGARGARGARMGNAAR GCNMGNGARTTYCAYGCNAGYYTNYTNCCNAGYGAYAGYCCNGAYCARYTNCCNGCNAAR AARACNMGNCCNYTNACNGCNGTNGARCCNTTYAGYYTNGCNGTNGAYGARMGNGGNAAR AARTAYCARGARGARTTYAARTCNAAR---ATHGARGARGARGARGGNCARGCNAARTCN AARGCNCARTTYCAYGCNTCNTCNAAYAARGTNGTNTTYAARGCNCCNTTYGTNCCNGAR AARTCNAGYMGNCCNYTNACNGARATGAGYAGYTTYACNYTNAAYACNGAYCARMGNGCN GTNAARMGNGARTTYTTYAAYCARCARYTNAARGCNCAYGARGCNGARGTNGARTCNYTN AARMGNCARMGNGARGAYMGNAARGTNAARGARGARAARGARGCNGTNGCNCARYTNMGN CARGAYATGGTNCCNAARGCNACNGGNATHAARAARTAYAARCARGTNACNCCNGCNCCN AGYGAYAARCCNYTNACNGTNGCNCARTCNCCNTGYYTNACNAAYMGNYTNMGNTCNGGN MGNGAYACNTCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNGTNCARTTYGTNMGNAARCAYGCNYTNCAYTCNCCNGARMGNACNGTNTTY GCNGAYGGNCARTAYAGYGARGGNYTNAARCAYCAYGCNMGNYTNGTNACNACNTTYGAY GARGCNGARYTNTGYCCN---------------GARTAYGARCCNTTYGAYGCNAGYAAR AARAGYMGNATHGAYGAYGARYTNYTNCCNAAYYTNGAYGAYGCNGTNYTNMGNACNGCN MGNATGMGNAARAAYCARATHGCNAARTGYAARTCNGTNGCNMGNAGYACNGTNACNAAY TCNGTNAARTAYTAYAGYAAYGTNACNGTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHMGNAARYTNGAYGAYGARTCNTCNTTYCCNTTYGCNGGNMGNGAR GGNCARGTNGCNTGYAGYGTNTCNAAYAARATHTAYGTNTTYGGNGGNGTNGARCARGGN CARGGNGAYGARCCNAARGARACNAAYGARYTNYTNATGTTYGAYYTNGCNTCNCARAAR TGGTCNAARCCNGTNGTNCAYGGNTCNCCNCCNCCNGCNMGNTCNGCNGCNTCNYTNGTN GCNGTNGGNACNAARYTNTAYYTNTTYGGNGGNYTNAGYCAYATHTGYGGNTGGTTYGAY GAYGTNTTYACNTTYGAYACNGTNTCNAGYACNTGGTCNATHYTNGARACNGARGGNTCN AARCCNMGNGCNMGNGAYAARYTNCARGCNGTNGCNATHGAYACNAAYATHTAYTAYTTY GGNGGNTTYGGNCCNAARTCNGAYGARGCNGARGTNGAYGAYYTNGCNGGNGAYGAYGAY GAYGAYTAYGARGAYGARGARGAYATHCCNGARAGYMGNGARCARGAYGGNGCNGARTTY GGNTGGTTYAAYGAYYTNTGGGTNYTNGAYACNYTNACNYTNAARTGGTTYCARCCNATG CARATGAAYYTNGGNGTNCCNACNCARMGNGCNGCNCAYGGNATGTGYGCNGTNGGNMGN AAYATHGTNATHTTYGGNGGNMGNGAYATHGARGAYMGNCARAAYGAYYTNCAYGTNTAY AAYATHGAYTCNMGNAARTGGGAYACNGAYYTNAARATHAGYGGNCAYGCNCCNGCNCCN MGNTCNTTYCAYAGYGTNACNGCNGTNGGNGAYAARGTNGTNGTNTTYGGNGGNMGNGGN MGNGARAAYAAYCAYTTYTCNGAYTTYGAYGTNYTNGAYYTNGARAARAARGARTGGTCN MGNGCNGCNGTNGARGGNTAYCARCCNYTNGCNMGNGGNCARCAYTGYGCNYTNACNGTN GGNGAYACNTTYYTNGTNTTYTGYGGNTCNGGNAAYTTYAGYCCNGARATHATGCARTGY CARACNTTYTAYACNGAYACNTTYTTYATHAARACNGAYTCNTTY---TCNGARGGNAAR AARGCNAAYGGNGARCCNGCNGTNACNTTYACNACNATHGGNGGNGTNYTNGAYTTYTAY GTNTTYGTNGGNGAYTCNCCNGCNGAYGTNACNTCNCAYTAYATHAARTCNATHGGNYTN CCNGCNTTYCCNCCNTAYTGGAGYYTNGGNTTYCAYYTNTGYMGNTGGGGNTAYAARAAY ATHACNCAYATGMGNCARGTNGTNCARMGNACNYTNGAYGCNGGNATHCCNGTNGAYCCN GGNGTNGGNAGYGAYGCNTCNYTNTCNACNTAYGAYATGTAYCAYAGYTCNGARGTNTGG CCNGGNCCNACNGTNTTYCCNGAYTTYACNAAYCCNGARAGYGARGAYTGGTGGMGNCAR CARATHYTNCAYTAYGCNGARACNGTNGGNGTNGAYGCNYTNTGGATHGAYATGAAYGAR CCNGCNTCNTTYATHCCNCCNTCNAARATGYTNTGY---GARAAYAAYACNTGGAAYTAY CCNCCNTAYTGYCCNAAYATHGAYGAYTGYGTNATGTAYGAYAARACNATHTGYATGGAY GCNMGNCARAAYYTNAGYYTNCAYTAYGAYGTNCAYAGYYTNTAYGGNCAYTCNATGGCN ATHMGNACNTAYAAYGCNYTNTCNACNYTNAARAGYGCNMGNCCNTGGACNATGACNMGN TCNTCNTTYGTNGGNACNGGNMGNTAYGCNACNAARTGGATGGGNGAYAAYAGYGCNACN TGGCARGAYATGMGNAAYTCNATHATHGCNATHYTNGARTTYGGNTTYTTYGGNTTYGCN ATGAAYGGNGCNGAYATHTGYGGNTTYTGGAAYGARCCNTCNTAYGARYTNTGYGTNMGN TGGCAYCARYTNGGNGCNTTYTAYCCNTTYGCNMGNAAYCAYAAYGGNAARGGNGAYGCN CCNCARGAYCCNGCNTCNTTYGGNCCNGAYTTYGTNGARACNGTNMGNCCNGCNYTNATG GCNMGNTAYMGNYTNYTNCCNTAYYTNTAYACNTCNATGTAYGARGCNCAYACNGARGGN CAYYTNGTNATGCARCCNYTNTTYTAYCARTTYCCNCAYGAYAARGCNACNYTNGAYATH GAYMGNCARTTYATGYTNGGNGARGGNYTNYTNGTNTCNCCNGTNYTNGAYGARGGNAAR ACNAGYGTNGARGCNTAYTTYCCNGARGGNMGNTGGTTYGAYTAYACNACNGGNGARMGN AGYGARMGNGGNGGNACNAAYGTNACNYTNGAYACNCCNYTNAAYAARTTYAAYGTNCAY ATHMGNGGNGGNCAYGTNATHCCNGTNCARAARCCNGCNGTNAAYACNTTYGARAGYMGN CARAAYGARYTNGGNYTNYTNGTNGCNATGGAYGARTCNGGNMGNGCNAGYGGNCARATG TTYTGGGAYGAYGGNCARTCN------AARYTNGARGTNTAYAAYTTYATHACNTTYACN ATHGAYAARGGNACNYTNMGNATHGARCCNAARGTNTCNAARYTNACNACNGGNYTNAAR TTYGAYACNGTNGARATHTAYGGNYTNACNMGNATHCCNGCNAAYGTNAARGTNAAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNACNCAYAARMGNATHYTNMGNTTYATGCAYYTNTAYTTYAARGAY YTNCCNCAYCCNGCNTAYATGAARAARTCNATHAARGARYTNGGNATHGGNACNTAYGAR AAYGTNATHACNGCNACNCCNGAYATGACNYTNATHAARGTNYTNAAYYTNTTYTCNGAY CAYMGNATHTCNGCNYTNCCNGTNGTNGAYAAYGAYTCNGGNAARATHATHGGNATHTAY GCNAARTTYGAYGTNATHAAYYTNGCNGCNGARAARACNTAYAAYAAYYTNGAYATHACN YTNAARGCNGCNYTNGAYMGNMGNTTYGAR---AAYCAYCARGCNGGNGARAARGTNGTN TCNTGYCARTCNTCNGAYTCNYTNGARGAYGTNGTNAAYAARATHGTNAARGCNGARGTN CAYMGNYTNGTNGTNGTNAAYGARTCNGGNGCNGTNGARGGNATHATHTCNYTNTCNGAY YTNYTNAAYTAYACNGTNYTNMGNCCNATHGARGARGTNTCNGARGAYGAYTTYGTNGCN YTNGGNACNCCNYTNCCNGARYTNGAYGARACNGARGTNCCNAARAARCCNACNACNATH CARGAYYTNACNGCNAARGAYMGNGARGGNMGNMGNMGNTTYCAYGGNGCNTTYACNGGN GGNTAYTCNGCNGGNTAYTTYAAYACNGTNGGNTCNAARGARGGNTTYACNCCNTCNACN TTYGTNTCNTCNMGNAAYCARAARCAYGARGAYAARCARTCNGCNMGNCCNGARGAYTTY ATGGAYGAYGARGAYYTNGAYGARCAYGGNATHGCNCCNMGNAARTTYGCNACNGCNGGN AAYTAYACNTCNGARGARMGNAARMGNAARTTYGAYMGNATGGCNTCNCARYTNACNMGN TCNTCNTCNYTNGAYYTNGGNAGYGCNYTNACNGAYYTNGTNGTNCCNGARTAYYTNCCN ATHGGNATHAARYTNYTNMGNAARATGGGNTGGMGNGARGGNCARGGNYTNGGNCCNMGN GTNAARAARAARAARAARMGNGGNMGNAARAARGGNGCNTCNGAYGGNAARAARATHTAY GGNTGYGCNATGCCNCCNYTNGARTCNGARAGYGARGAYTCNGAYTCNTTYATHCCNGCN AAYGTNAGYGARYTNACNTTYGCNCCNTCNGAYATHACNCCNATHACNYTNCARGCNAAR GAYGAYGTNAARGGNYTNGGNTAYMGNGGNYTNGAYCCNTCNYTNGCNYTNCCNGGNTCN CAYATHAAYYTNTTYGGNAAYCCNGTNMGNGGNAARAAYAARGGNAARGGNATHMGNGGN CAYGCNTTYGGNGTNGGNGCNYTNGARGAYGAYGAYGAYGAYATHTAYGCNCARGAYAGY YTNTCNAAYTAYGAYGTNACNATG---AARGAYGGNGAYGAYGAYGAYGGNAAYTTYGGN TGGACNGCNCCNMGNGTNCAYGGNAARCARAARYTNCCNGTNTCNTAYGTNGGNAARYTN YTNGARGGNTTYTGYYTNTCNTCNAARCCNYTNCARCCNMGNAARACNTTYCCNCCNCCN AARYTNCCNCCNAAYTTYMGNCCNMGNCAYTGGTCNMGNMGNMGNAAR---------AAR GAYGARGAYTCNAAYGGNGGNCARAAYAARATGACNGCNATHGAYMGNGGNYTNATGYTN GGNGARACNCCNATHATGAGYTCNGTNTTYGAYYTNGTNGGNTCNAARGAYAARACNMGN ATHGARTGYGCNAARGARGCNATHGARATGACNMGNTGYYTNGAYAGYGCNAARGGNAGY AAYTCNTCNGARTCNGTNMGNAAYGGNAGYAARAARGAYGGNGAYGAYGTNGTNAARYTN TCNGAYGARAARAARACNACNGARAAYCCNAAR---------------TTYTTYTCNMGN TTYGTNGARGCNAGYACNACNGARTCNAAYAAYAGYAGYGGNGAYAARGAYTAYGCNGCN CCNGGNACNCCNYTNTTYAARGGNTCNYTNAGYYTNCARCCNTTYMGNAARGAYCCNGCN AARCARGCNMGNTTYGAYCARTAYATGGCNGCNYTNCARCARAARGCNCCNGAYCCNTAY AGYCAYGTNTCNMGNAARAGYATGACNGARTGGGARAARGCNMGNGARMGNGAYGARTTY AGYMGNTCNGCNMGNYTNTTYMGNCCNATGTCNGCNATGATGTCNTCNMGNTTYGTNYTN GGNCCNATGYTNGAYGAYAARGAYCARGAYTCNAARACNGARACNGGNGAYGARGTNACN GAYCARGTNAARGCNGCNGARATGMGNATGTTYGGNAARYTNACNMGNGAYGARTTYGAR TGGCAYCCNGAYAARYTNYTNTGYAARMGNTTYAAYGTNCCNAAYCCNTAYCCNGGNTCN GAYATHGTNGGNYTNCCNAAYGTNAARMGNGAYAARTTYTCNGTNTTYAAYTTYYTNAGY TTYGGNGAYTAYCARCCNAARGARACNGAYACNCAYATHGTNACNGARGAYAARGAYGTN TCNGGNAARTCNCARAGYAGYTCNYTNAARGTNGAYCAYCCNGAYCCNGGNAARAARAAR GCNACNYTNTCNTCNATHTTYAARGTNYTNGAYGAYCCNGAYTTYCAYAARCCN------ ------CCNACNAGYAGYAARTCNGAYGARYTNCCNGCNGARAAR---CCNTTYMGNGGN AAYGARGARGGNGAYGGNAAYGTNGAYGAYGARGARGARCCNGAYGTNGAYYTNTTYMGN GCNATHTTYAARAAYTCNGAYTCNGAR---------GAY------TCNGARGAYGAYAAR AARTCNAAYGARGAYGGNGAYGARTCNATGAGYGGNGAYGARGARAAYAAYMGNAARACN GAYGGNGGNGAYTTYAAYGAYGAYATHGAYGAYGAYAARCAYTCNGTNATHCCNTCNAGY YTNTCNMGNGTNTCNGGNTCNGGNGGNCCN---------------------------AGY CCNAAYTCNAAYYTNTCNATHCCNGGNGCNATGGGNGAYGCNCCNAAYGCNAGYGTNMGN TCNAAYCCNGCNTCNTCNATGMGNCCNGCNMGNACNMGNTGGGAYGCNAARTCNGTNTTY AGYGTNYTNGAYGARATHAAYAAYGAR------ACNATHCCNTCNGCNGAYMGNAARCCN ACNGARATHAARGAR------------GAYATHTCNGAYTCNGARTAYGGNCCNGCNYTN CCNCCNCCNCCNTCNGAYGGNCCNYTNCCNTTYMGNACNGGNGGNGGNAGYYTNATHGTN AARCARAARGAYGCNAARAARGAYACNACNMGNCAYMGNCAYMGNGAYAARCAYAARCAY AARAARGAYAARAARAARAARTCNAARCAYAARGARAARAARAARCCNAARAARAGYAAR AARTCNTCNTCNAARTCNMGNAARTCNMGNCCNGAYAGYTCNGGNAGYGARGCNGAYTGG GAYACNACNGAYGAYTCNGAYATGTCNGAYAARGARYTNYTNAAYMGNTTYATHCARGTN TCNAARATGAARTCNGGNTCNYTNGCNGTNTGYATHCARTTYGARAARGCNCARGAYGCN MGNAARGTNYTNGARGAYAARGGNATHTGGGAYAGYAGYMGNAARYTNCARMGNAAYGGN GARTCNGTNGCNGTNCCNGTNYTNGGNCAYGAYMGNTCN--------------------- ---------------------------------CARYTNTCNATHTTYAARGARYTNCCN YTNCCNMGNTCNGCNCAYGCNYTNYTNTCNGARGTNCCNAARAARTGGGARMGNCAYGGN AAYYTNATHYTNYTNCCNTCNTCNGCNTTYGCNTCNCCNCARTGGGAYCARYTNGGNGAY GARYTNTGGCARGTNGTNGCNTCNTCNYTNTCNTGYGAYMGNYTNGCNMGNCAYTCNACN GTNACNAGYGAYGGNTTYMGNACNCCNCARGTNTCNATGYTNYTNGGNGAYGAYGGNAAR GTNATHCAYGTNGAYAAYGGNATHAARTAYAGYTTYGAYGTNACNAARTGYATGTTYAGY TCNGGNAAYATHAGYGARAARYTNMGNGTNGCNTCNTGGGAYTGYTCNCARGARGTNGTN GTNGAYYTNTAYGCNGGNATHGGNTAYTTYACNYTNCCNTAYYTNGTNCAYGCNAARGCN MGNCAYGTNCAYGCNTGYGARTGGAAYCCNGAYGCNGTNGARGCNYTNMGNAGYGCNYTN YTNYTNAAYGGNGTNGCNGAYMGNTGYACNYTNCAYCCNGGNGAYAAYMGNCARYTNCAR YTNTCNTGYGTNGCNGAYMGNGTNAAYYTNGGNYTNATHCCNACNAGYGARGAYGGNTGG TGYGTNGCNGCNCAYGTNYTNAARCCNGARGGNGGNGTNYTNCAYATHCAYCAYAAYGTN ACNACNACNTGY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGYGARGAR YTNAARYTNCARAAYATHCARAARTTYATHGARGGNATHMGNACNGARYTNGTNTCNTGG TGGGAYMGNTGYTTYTTYGAYCCNCARCARMGNAARAGYTTYACNYTNTAYCAYGARGAY AAYTTYACNGARGCNYTNYTNGARGCNCAYGARAARGARYTNGARAARGTNMGNGAYTAY TAYAARGARCAYMGNGAYATHYTNGAYAARGTNACNAARMGNGARGARYTNTTYAARTCN ATGGTNGTNTTYGARTCNAARGCNAGYGAYCCNAARMGNTTYTTYNNNGAYMGNGGNGGN AARYTNYTNGTNGARGARAARCARMGNAARAARATHYTNAARGAYYTNCCNAARATGGAR GARGARGTNTCNGARTTYATHAGYCAYTGGGARCARGCNAAYCARAARGARTTYTTYGTN AAYGGNGTNMGNTTYCCNCARTAYGTNATHMGNCARTGGGARGAYTTYCAYMGNCAYAAR GARCARGARAARCARGAYMGNATGAARGCNMGNGCNAARCARACNCARGARGARATHATG TTYGGNAGYAARTCNGCNYTNATHACNCCNAGYAARAARAARAAYGGNGCNCCNACNACN CCNATGMGNACNCCNYTNAARGCNMGNAARYTNAAYGGNCCNGTNAARACNCCNAAYACN ACNGGNMGNYTNCCNCCNGTNAGYMGNATHCARCAYAGYACNGTNTTYCAYTCN---CCN YTNTGYACNCCNAARACNCCNYTNACNGCNTCNAGYAARAARMGNMGNTCNATHMGNYTN ATGCAYAARGCNGCNACNGARMGNAARAGYTCNAAYTCNAARMGNMGNMGNTCNMGNGAY ATHTTYTCNCAYACNACNGTNAGYAGYGAYAAYAAYACNACNTCNTCNYTNGCNTCNACN TGYTCNTAYAAYGARTTYGCNAAYGGNYTNTCNMGNCCNAAYTGYMGNAGYAGYGTNGCN CCN------------ATGGARMGNGCNGTNGAYACNYTNGARGGNATGTTYAAYAARGCN GARAARGAYYTNGAYTAYATGTCNMGNAARYTNGAYMGNCARYTNGARAAYGTNAARGAR GGNGAYCCNAARGCNAAYCCNGTNAARYTNATGAARAARYTNGARYTNATHAARACNGAR TAYGCNAAYGTNGTNCARGAYGTNMGNGCNATHCARGARGCNCARAARGARTTYTCNGAY TCNTTYMGNGARCARYTNYTNACNYTNACNGAYGTNYTNCARAARYTNGARACNAARACN GGNCARTCNTCNGARAARACNGAYGARGARMGNYTNGCNTTYGAYCARYTNTCNAGYYTN YTNGGNGTNCCNCCNGGNCARYTNGARTCNCARAGYCARGCNTGYACN---------GAY AGYGTNAAYGARAAYGGNAAYGGNGTNCCNTCNGARTCNTCNTCNTCNGARGCNGTNACN ACNGGNGCNMGNTCNAARGAYGGNAARAARAARAARTCNAGYCARGAYTCNGCNAAYTCN ACNCARMGNAARAAYTCNGARGARTTYTCNGARATHACNGARGARGARTTYCARGGNGTN TCNAARYTNATHACNCARMGNTGYAARYTNGARGAYGTNAAYAARGTNTAYMGNMGNYTN TGGCARCAYTTYMGNGARGARAARAAYACNACNAARYTNAGYCCNAARGAYATGAAYGCN ATGGGNYTNMGNGTNACNGGNGCNACNGGNGARGCNAARYTNAARGTNYTNMGNGCNYTN AARYTNTGYCARYTNAGYMGNGAYGGNGARGTNATGGTNGGNTTYATHGTNCCNAAYTCN AGYYTNAAYTCNTTYGGNTCNATHTGYTAYTGYATGATHACNYTNGGNATHCAYGCNTAY GCNTGYTAYAARGAYATHGTNMGNTAYCARGARGCNGAYGARMGNGCNTGGCCNAGYAAY GGNGGNGARCCNCCNACNGARGTNACNTCNYTNYTNGGNTTYACNATHYTNTCNYTNYTN GTNATGCCNTTYTTYTGYGCNGCNTCNTTYATHAARGTNGGNAAYYTNGCNAAYGAYGGN GTNAARYTNGGNMGNGAYAAYACNCAYGARGCNGCNGCNGCNGAYGTNAARGARAARAAY AAYTCNGTNGCNTGYGGNMGNAARTGYYTNAARAARYTNTGGAARCAYTTYTGYCCNGTN GCNCARACNATGCAYYTNTTYGCNGCNTTYTCNYTNYTNYTNCCNGARGTNYTNYTNACN GCNGCNGAYATHGCNTGGGARAGYGARYTNGAYTTYYTNTTYCCNGARGAYMGNGCNATH ATGAGYCAYATHATHAGYAGYGTNAAYYTNACNACNCAYCCNAAYGCNACNMGNYTNGCN GTNCCNTCNACNMGNGTNTCNCCNGGNGGNTGGGGNGAYMGNATHAGYGTNAGYATHGCN TTYGTNCAYTTYTGYATHGCNYTNGCNTGYTTYYTNGTNMGNTAYGCNTCNGTNTTYTGG TAYACNAAYAARCCNYTNACNYTNGTNTTYGCNTTYCARYTNYTNTCNATGGTNYTNAAY TCNATHTTYGGNTTYAAYAGYTTYGCNACNYTNTAYTGYGTNTGYTAYAAYCARAARATH TTYATHAAYGTNAGYYTNTCNATHAGYTGYGGNTCNGCNYTNACNYTNTAYYTNATHAGY GGNGCNATHYTNYTNYTNTCNACNATHACNGCNTTYGARTAYGGNTCNCAYTAYTTYCAY GARAARTCNAARATHGTNGARMGNAGYCAYGCNTCNGAYACNTAYACNAARMGNACNGTN ATHGTNAAYAGYGGNTGYCARGGNTAYATHCCNCAYTCNTGYGCNATGGGNTTYYTNGTN GCNTTYGCNATGTGYAARGCNCCNYTNATHTAYGAYATGGTNCAYYTNATGMGNYTNACN AGYGAYGARYTNATGGTNTCNGCNGTNATHTGYGARGTNTGYTAYATGGTNACNTGGGTN ATGYTNTGGTTYGGNYTNACNGTNAARCARAARTGGAARTTYMGNATHYTNGAYTAYGTN ACNYTNCARGAYTCNTCNACNTCNCARMGNATHGTNTCNMGNMGNTAYAGYGAYCAYGCN GARAAYCCNYTNAAYAARGARTAYMGNAAYAGYYTNMGNGGNAARTGYGAYGARATGTAY GCNTCNGARACNAAYACNGCNTCNACNTGYGARGAYYTNCCNACNYTNATGTCNTCNTTY MGNGAYMGNGTNMGNGARTCNTCNYTNGCNGCNAGYAGYTTYAARGARMGNGARAARAAY ATGTTYGARMGNTAYCAYACNTAYCARATHGGNATHCARGAYAARYTNGGNMGNTCNTTY TTYAAYGTNTCNTGYGARGCNYTNGCNAARAAYYTNYTNGGNCARAAYATHGTNMGNTCN ATHGGNTCNCARATHATHAARGGNCARATHGTNGARACNGARGCNTAYATHGGNCCNGTN GAYAARGCNGCNCAYAGYTAYCARGGNAARMGNACNCCNMGNAAYGARGCNATGTTYATG ATHCCNGGNACNAGYTAYGTNTAYAAYATHTAYGGNATGTAYTGYTGYATHAAYATHTCN AGYAARGGNGAYGGNTCNGCNGTNYTNYTNMGNGCNYTNGARCCNYTNCARGGNCARGAR YTNATGGCNGARGGNMGNAARGTNAARACNGAYAAR------AAYAARAARCCNTTYAAR GARMGNGAYYTNACNAAYGGNCCNTCNAARYTNTGYCARGCNTTYCAYATHAAYAARAAY GARTTYGAYAARGTNGAYYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------ACNAARGGNAGYTCNGGNGGNATGATGGTNTGYTAYTAYACNAAYTGGGCN CARTAYMGNCCNGGNTTYGGNAARTTYACNCCNAARGAYYTNGAYGCNACNYTNTGYAGY CAYATHCAYTAYGCNTTYGCN---AARYTNTCNAAYCAYATGATHGCNCCNTAYGARTGG AAYGAYGARAGYACNGAYTGGATGGTNGGNATGTAYGARAARYTNAAYGGNYTNAARAGY TCNCAYCCNGGNYTNAARACNATGYTNTCNYTNGGNGGNTGGAAYYTNGCNTCNGGNCCN TTYTCNAGYATGGTNGCNTCNCCNGARMGNMGNGCNGTNTTYATHAARAGYGTNGTNYTN TTYYTNMGNAARTGGAAYTTYGAYGGNYTNGGNATHGAYTGGGARTAYCCNGGNTCNMGN GGNAGYCCNGCNGGNGAYAARGARAARTAYACNYTNYTNGTNGARGARACNATGGCNGCN TTYAARCARGARGGNGARAAYTCNGGNYTNCCNMGNYTNYTNYTNTCNGCNGCNGTNTCN GCNGGNAARAGYACNATHGAYTCNGCNTAYGARGTNGAYAARGTNACNAGYGTNYTNGAY TAYGTNGTNGTNATGACNTAYGAYTTYTTYGGNGCNTGGAAYCCNTAYACNGGNYTNGTN AGYCCNYTNTAYCCNCCNMGNAAYGCNACN---GGNATHGARGCNGTNTTYAAYGTNGAY TAYGCNGTNAARTAYTGGGTNTCNAARGGNTGYCCNAARAARAARYTNGTNGTNGGNGTN ATHTCNTAYGGNMGNTCNTTYACNYTNACNAAYCCNGCNGTNTCNGGNYTNMGNGCNCCN ACNAAYGGNGCNGGNTCNCCNGGNMGNTAYACNMGNGARGCNGGNTTYYTNTCNTAYTAY GARGTNTGYTCNATGATHAARAAYGGNGCNMGNGTNATHMGNYTNGGNGAYGARAARGTN CCNTAYYTNGTNYTNGGNAAYCARTGGGTNACNTAYGARGAYCARGCNAGYATHGCNATH AARGCNGAYTAYATHGTNMGNGGNGGNTAYGCNGGNGGNGCNYTNTGGGCNACNCCNYTN GAYGAYTTYCARGGNAGYGTNTGYGGNGARGGNCCNTAYCCNATHYTNTCNACNGTNTCN AARAARYTN--------------------------------------------------- ---------------------------------------------YTNAAYGGNTGGGTN AAYTTYTCNTGGTGGGAYGARATHMGNACNTGGGAYCCNTCNGAYTAYAAYGGNATHGAY GTNYTNCAYCCNGAYCCNYTNGAYATHTGGMGNCCNMGNACNATHATHGCNAAYTCNGTN GGNCARMGNGAYATHTTYGARGAYGAYTAYGCNCCNYTNTCNATHYTNCCNTCNGGNTCN ACNACNTGGTCNCCNGGNGCNATHTTYTAYYTNACNTGYGARTTYGARYTNACNTTYTTY CCNTTYGAYACNCARACNTGYCARGCNMGNATHATHGCNAAYGARYTNGCNCAYGARATH AAYATHATHCCNACNCARCCNTTYGTNATHAGYGTNAGYTAYACNAARCAYGGNGARTGG GARYTNAARTCNACNTCNGTNACNAAYGCNGTNYTNGTNGTNGGNGGNMGNCCNTTYTAY GTNMGNACNATHTCNTTYACNTTYGARMGNMGNCCNACNTAYTAYATHYTNAAYGTNYTN AGYCCNGTNATGGTNYTNTCNTTYYTNTCNYTNTTYAGYTTYGTNGTNCCNAARGAYAGY GGNGARMGNATHTCNTTYTCNATHACNGTNYTNYTNTCNYTNGCNGTNTTYATGGGNGTN GTNTCNGGNCARYTNCCNGCNAGYTCNGAYACNTTYCCNTAYATHAGYATHTAYATHTTY AGYYTNYTNTGYYTNAGYGGNTTYTCNACNTTYATHATHGTNTGYCARYTNMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GARCCNGARACNMGNGTNCARGARGGNCAY CCNACNCARYTNCAYTTYTTYYTNCCNCARYTNGCNGAYAGYATGAGYGARGTNTCNGGN ACNGCNACNGCNMGNAGYTAYTAYCARGARCARMGNYTNGARYTNYTNTCNMGNAAYGAR GGNGAYTAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARCCNGAYATHGCNAARGARATHATGAARAAY TTYYTNGCNMGNTTYCCNGCNATHGAYTCNTTYACNAARAARTGYTGYTCNTAYGCNAAR GARTAYGGNTAYACNGARACNATHTGYGGNMGNMGNMGNGAYTTYCCNTAYATHAAYAGY ACNTCNCCNGCNYTNMGNGCNCARGCNCARMGNCARGCNGTNAAYTTYTGYGTNCARGGN TCNGCNGCNGAYATHTGYAARYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNAAYTTYCCNATHGARACNACNTGGGAY GGNCARTGYGTNTGYCAYGAYCCNGTNAAYATHACNYTNGAYGARAGYGCNAAYGGNGAY YTNYTNYTNAARGTNGCNGCNCCNTTYTTYAAYAGYCCNGCNAARCCNGAYGGNCCNGCN GGNCARCCNTTYCCNCARYTNTGGGAYTAYGARGTNGTNGARGCNTTYTTYYTNAAYGAY CARGAYCARTAYYTNGARGTNGARYTNAGYCCNCAYGGNCARCAYYTNYTNYTNYTNYTN AAYGGNMGNMGNAARATGGTNAARGAYAARYTNCCNYTNACNTTYACNGCNAGYATHGAR GGNGAYAARTGGACNGGNGARGCNGTNATHCCNMGNGAYTAYYTNCCNTCNGCNGTNACN AARTTYAAYGCNTAYGCNATHCAYGGNGARGGNGAYGAYMGNCARTAYGARTCNYTNTAY TCNGTN---------ACN---------CARGGNATGCARCCNGAYTTYCAYMGNYTNGAR YTNTTYMGNCCNYTNGCNATGAGYGAYGTNYTNAGYAAYTAYGAYCCNTCNMGNGTNTCN CCNYTNTGG--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ACNCARGARGCNGTNTTYTCNATHGTNGGNAARAARATHATHGARAGYTGY GTNGCNGGNTAYAAYGGNACNATHTTYGCNTAYGGNCARACNGGNTCNGGNAARACNTTY ACNATGYTNGGNCCNTCNGARAAYGCNGAYAGYTTYCARCAYGARYTNMGNGGNGTNATH CCNMGNAGYTTYGARTAYYTNTTYAGYYTNATHGCNCAYCARCARGARYTNCAYGGNAGY AARMGNCARTTYYTNTGYMGNTGYTCNTTYYTNGARATHTAYCARGARCARATHTTYGAY YTNYTNGAYCCNACNTCNCARGGNYTNCAYYTNMGNGARAAYATGAAYAARGGNGTNTTY GTNGAYGGNYTNATHGARCARGTNACNTGYAGYCCNAGYGAYGCNTAYCARGTNYTNATH ATGGGNTGGYTNAAYMGNMGNGTNGCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CAY CAYTTYATHGGNTCNATGACNYTNAARGCNYTNYTNGARGAYCCNAAYYTNAARAAYCCN CCNATHATHGGNCARTCNAGYGAYYTNGTNAARGTNAARAARGARGAYGGNGGNTCNGGN GTN---CARTAYAAYTAYGGNTCNGCNTTYYTNGGNCCNAAYYTNTGGGAYAARTCNTAY GGNATGGAYYTNAAYYTNGARTAYATGGAYYTNGAYGARTTYYTNTCNGARAAYAAYATH CCNGGNAGYGGNGARGARGGNYTNGCNGAYATHGGNYTNGGNGCNGAYAARGAYGAYGAY GAYCCNYTNMGNATHGGNGGNAAYACNYTNCCN---AAYCCNGCNGTNAGYTCNCCNMGN CARTAYYTNMGNACNCCNCCNYTNAGYCCNACNCAYTAYACNATHAARGGNTCNTCNGTN ACNCCNCARGCNAAYCCNACNTCNACNCCNTTYCCNTCNCAYATHTCNCCNTCNTCNAGY CCNCCNGGNAGYCCNTCNATHAAYGTNGAYTTYCARGTNTCNGAYCARGAYYTNGCNYTN ACNTCNATHCCNGAYTAYGAYGAY------------CCNMGNTAYAGYGCNGGNGGNTGG ATHCARGGNGGNGAYGGNCAYMGNCCNAARATGGGNATHAGYTTYGAYCCNMGNAARMGN AAYTTYACNGARGARGARYTNAARCCNCARCCNATHATHAARAARTCNAARAARATHTTY GTNCCNGARGAYYTNAARGAYGARAARTAYTGGGCNMGNMGNYTNAARAAYAAYTAYGCN GCNAARMGNTCNMGNGAYGCNMGNMGNGTNAARGARAAYCARATHGCNYTNMGNGCNGCN TAYYTNGARAARGARAAYACNTGYYTNAARGARGARATGGTNAARYTNMGNAARGARAAY GCNAARYTNAARAAYATHGCNGAYAARTAYGARCCNGGNACNGTNGCNGCNYTNGCNTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARAARTCNMGNCCNGTNAGYGCNTCNAGYYTN MGNGARGCNGAYGCNGCNMGNTCNMGNCCNMGNTCNGGNTCNAARGGNGGNCCNCAY--- TCNCARGCNGCNTTYATHACNCARAARAAYGARMGNTCNYTNMGNTAYGARGCNACNAAR CCNGTNTAYGTNTTYCCNAARCARTCNCCNACNAARCCNMGNMGNAAYTCNGAYACNGGN CCNYTNATHMGNTCNAAYAGYCARTCNGGNYTNATGATGATGCCNCARACNGAYGTNATH CAYGCNTCNAGY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNYTNYTNACNTGYGGNGGNACNATHGAYAARCARTAYCCN CARGGNCCNAGYGCNTAYGCNTTYGARTTYGGNGARGCNGCNGTNGARAARATHYTNGAR MGNGTNTGYCCNTCNTTYAAYTAYCARATHGARAGYATHTGYACNAARGAYAGYCARGAR ATGACNGAYAAYGAYMGNGARGAYATHYTNMGNGCNGTNGTNGAYGGNGAYCAYCARCAY ATHYTNATHACNCAYGGNACNGAYACNYTNTGYGAYACNGCNCAYTAYYTNGTNAARTCN GGNGTNGGNCARGGNTCNAARTTYGGNCCNGGNGTNGGNGARAARTCNGTNGTNYTNACN GGNTCNTTYAARCCNGARGCNATGAARGAYTCNGAYGCNGAYTTYAAYATHGGNTTYGCN ATHGGNTTYYTNCAY---TCNTCNACNCCNGGNGTNTTYGTNGCNATHGARGGNAGYATH YTNGAYGGNGGNCAYGTNATGMGNTGYGARGAYGGNAARTTYGTNGAYGARMGNTTYGTN YTNAARMGNTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARCCNTTYCCNAARTTY YTNAARGAYATHYTNATHCCNTTYYTNAARMGNATGTGGGCNAARMGNCCNCARTGY--- TGYTGYAARAGYAARAAYCARGTNACNGAYAAYGAYGCNGARACNGAYCCNACNGCNAAR CAYTCNGAYCAYAARTCNTTYYTNGARMGNGARMGNGCNAARCCNGAYYTNGGNGAYTTY ACNYTNGGNGARTAYACNGARAARGTNATHYTNTAYGGNTTYYTNATGYTNTTYGCNTGY TCNTTYCCNYTNGCNCCNATGYTNGCNYTNYTNATHTGYTAYATHGAYATHAARGTNGAY GCNAARMGNATGYTNTGGTGGTAYMGNMGNCCNGTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATGYTNCARCARAAYTTYAARAARGAYTCNMGNGTNTGG YTNCAYAARAAYTCNMGNMGNAARCCNAGYGGNAAYGARACNGCNAARYTNGGNTTYGAY CAYCARAAYMGNGTNMGNATHAARACNGCNMGNGARGAYGAYAAYTTYGAYAAYATHCCN TAYATHACNGGNGCNGAYGGNATGGTNTAYAARAARGAYAGYMGNACNTGGYTNCAYAAR TCNTCNGGNMGNATGYTNTCNMGNTCNGGNMGNGCNGARACNMGNAGYMGNGCNAARGAR GAYATHAARMGNGTNATHAAYGCNATHGAYAARGTNMGNAARTGGGARAARAARTGGGTN ACNYTNGGNGAYACNTCNGTNACNATHYTNAARTGGGTNCCNGTNACNGCNCARGARAAY CCNGGNGCNYTNMGNAARATHCCNGGNGTNAARACNAARACNTAYTCNAARGCNMGNGTN GARMGNGARMGNGARYTNTAYAAYGCNGARACNAAYGGNYTNCCNMGNGCNAAYTCNCCN GCNGAYTCNACNAGYAAYAAYACNAAYATGTCNAAYACNAGYTCNCCNTCNTCNAARYTN CAY------AAYACNGARAARCCNAARAAYGGNACNGTNACNAAYAGYCARAGYTCNGTN GTNTAYTCNGARGARAAYACNCARCARTCNATHGGNTCNTTYGGNTCNGARAAYYTNAAY GARGAYTCNAAYATGTCNTTYCCNGARAAYAGYGGNYTNAGYGARCARGGNGAYCAYCAY GARTTYTCNCAYGAYAGYAAYGAYGCNGAYCCNGGNATGMGNGTNGCNATGAGYATGGTN GGNGAYGARGARCARGARGGNGARAAYAARACNGCNACNAARACNGAYMGNGCNCARCAR GARAARGARTCNTCN------TCNGAYGARCCNCCNGCNAARAARACNAARACNGCNTCN ATGTCNGARAARCAYAAYTTYGGNATHGCNCCNGTNACNTGYCAYGCNTTYAGYAARGAY MGNAAYGGNYTNGCNATGTCNYTNAAYGAYTCNAAYGTNAARATHTTYAARAARGCNGGN AGYAARTGGGAYGARACNGAYACNYTNAGYGARCAYGCNCARMGNGTNACNAGYATHGAY TGGGCNCCNAAYAGYAAYMGNATHGTNACNTGYTCNGCNGAYMGNAAYGCNTTYGTNTGG ATGYTNGARGAYGGNAARTGGAARCARGTNYTNGTNATHCCNMGNATHAAYMGNGCNGCN ACNTGYGTNAARTGGTCNCCNAARGARAAYAARTTYGCNGTNGGNAGYGGNTCNMGNYTN ATHGCNATHTGYTAYTAYGAYGAYGARAAYAAYTGGTGGGTNAGYMGNCAYATHAARAAR CCNATHMGNTCNACNGTNACNTGYYTNGAYTGGCAYCCNAAYAAYGTNYTNYTNGCNGCN GGNTCNACNGAYTTYAARTGYMGNGTNTTYTCNGCNTAYCARAARGARGTNGAYGARMGN CCNGGNGCNTGYAGYTGGGGNACNAARATGCCNTTYGGNGCNYTNATGGCNGARTTYAGY AAYGGNGGNGGNGGNTGGGTNCAYTCNGTNTCNTTYTCNGCNAGYGGNACNYTNGTNGCN TGGGTNGGNCAYGAYTCNAGYGTNTCNATHGTNGAYTCNTCNAARGGNAAYGARYTNGTN GTNGTNAARGARAGYTTYYTNCCNTTYATGAGYGTNTCNTGGATHACNGARAGYACNYTN GTNGCNGCNGGNTAYGAYTGYAAYCCNATGGTNTTYTCNTTYAGYGGNGGNAARATHACN TGYCARGGNAARYTNGAYGTNCCNCARGARAARGARTCNGGNACNATGAGYGCNATGAAY MGNTTYAARAAYYTNGAYAARAARGCNACNGAYAGYGAYAGYTCNCCNGARATGAARACN CARCAYCARAAYACNATHACNCARGTNTCNATHCAYACNGGNGAYAARCARAAYACNAGY AARATHGCNACNAGYGGNGTNGAYGGNAAYYTNATHYTNTGGGAYYTNAAR--------- ------CAYGTNGCNGGNGGNGGNGAYAARAARATHGARGTNGTNAARACNGARTGGAAY GCNAARTCNAARATHGGNTCNYTNGAYAAYGCNACNCAYAARCCNGGNGGNGGNGAYAAR AARATHGARACNGTNAARACNGAYTGGAARGCNGARTCNMGNATHGGNTCNYTNGARAAR GCNAAYCAYAARCCNGGNGGNGGNGAYAARAARATHGARACNGTNAARACNGAYTGGAAY GCNCARTCNAARATHGGNTCNYTNAAYAAYGTNAARCAYAARCCNGGNGGNGGNGAYATH CARATHGARTCNCAYCARYTNGAYTTYAARGCNAGYCCNAARATHGGNTCNYTN------ ---------------------------------------YTNTGYCCNTGYCCNGCNYTN ACNGCNTAYTGGACNAGYCCNCCNTCNTGYCCNMGNMGNGTNTGYTGYGARAGYAARTCN TCNTGYTGYTCNYTNATHTGYTTYMGNGAYTCNAARACNGTNTCNGTNTTYGTNGCNACN GTNGTNATHACNTAYTTYGTNYTNATGGAYATHATHYTNTAYTGYTAYTTYATGAARGCN AAYYTNGTNGARTCNTCNAARGGNGGNGARTCNGGNGARATHTAYACNCCNYTNACNCAY YTNTCNGTNAARGCNYTNYTNAAYGAYCARCCNAGYCARTAYYTNATHGCNCCNAGYACN GARTGGYTNGARTAYTTYACNAAYTTYGCNAAYACNTTYTAYTTYATHACNCCNAAYYTN GTNTCNTTYGCNCAYYTNATHGTNGGNTAYATHTCNGGNAARTTYGTNGCNTCNGARAAY YTNAAYGAYMGNMGNATHGGNGTNTTYYTNTTYGARTTYMGNACNTGGYTNGAYGCNTTY GAYGGNACNATHTTYMGNGCNCARGCNGGNAAYCAYYTNAARTAYAAYTCNATHCAYAGY TCNYTNGGNTAYTGGATHGAYGTNGTNTTYGAYAGYYTNGGNGGNTGYTTYYTNTGYTTY GGNATGTTYTTYTAYYTNYTNAARMGNTTYGGNCCNCCNMGNTTYGAR------YTNCCN TTYTGGTGY---GCNGGNCAYTCNGARGTNCARAAYACNGTNCCNYTNGTNAARGARGGN GGNGGNAGYAARGARACNTAYTCNGCNGCNCAYYTNYTNTGGAARGTNACNTCNTTYGGN YTNACNYTNYTNGTNACNGGNATHTGYTGGGAYAAYATHGTNGTNCARTTYACNGARATH TTYCARACNGARYTNCARGAYCCNMGNYTNTCNGCNYTNCARYTNGAYYTNTCNCAYTCN AAYACNACNGTNTTYATHTTYCARYTNTGGMGNYTNATHGGNTCNCARTGYYTNYTNAAY TAYATHYTNYTNATHATHTTYTAYGAYAARATHTGGGARTTYYTNAARGGNTGGCARTAY GTNATHYTNYTNATGGTNATHAGYYTNTAYGCNATGTCNGTNYTNTAYGTNAAYCARATH MGNACNCARYTNCAYYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNAGYMGNYTN CAYTCNCARGGNTAYAARYTNGGNATHGCNTCNMGNACNGGNGCNATHMGNGAYGCNGAR TCNYTNATHMGNYTNTTYGAYTGGGAYAARTAYTTYCAYTAYCARCARATHTTYCCNGAY TGYAARATHACNCAYTTYAARGGNYTNCAYAARTCNAGYGGNTTYCCNTAYACNGAYATG YTNTTYTTYGAYGAYGARCAYMGNAAYATHAARGAYGTNTCNACNYTNGGNGTNACNTGY ATGTTYGTNCCNGAYGARGGNGTNACNAAYGARTCNCCNAARGARGGNTTYAARYTNTTY GARTCNAAYAAYTCNAARMGNGGNAAYTCNTCNTCNGARGGNGAYGGNGARATHATHCCN AGYACNACNACNACNCCNGARAARMGNAARGARAARATGYTNTGGGAYTTYGGNTGYYTN GGNYTNYTNGARGARATHTCNYTNGAYACNMGNTCNAGYTCNAAYMGNCCNTCNAAYGAR AARCCNGTNTAYAAYTCNGAYGGNGAYGARACNMGNACNTCNGAYAGYAGYGCNAARATH GARGAYCAYGCNGCNGCNGAYCARGCNYTNGCNGAYATHGCNGARATHATH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TGGTTYCAYTGYAAYGGNTGYTAYAGYCARCCNGARCARGCNGGNMGNATHTTYTTYATH ACNAAYTGYAGYCAYATHTAYTGYGARAARTGYGTNACNGARTGYACNAARGARMGNTGY AARGTNTGYCARTCNAARTGYGCNACNATGGARYTNTCNGGNAAYYTNCARAARGARGTN GCNAGYYTNTTYGAYGARCCNGCNAGYATGGCNACNAARGCNGTNAARCARYTNAGYMGN ACNYTNGARTTYCARAARAGYCAYCARMGNMGNTGGTGYMGNCAYYTNAARGARATGYTN AARCARCARACNCAYCARTTYCARGARYTNAARAARYTNGCNATHYTNCAYMGNAAYYTN GARAARGARACNATGGARYTNAARAARGARAAYAGYTAYYTNAARTGYYTNYTNTCNAAR AAYATHMGNATGAGYTAYATGACNCCNGAR---------AGYATGGTNTCNACNACNGTN ACNCCNYTNTCNGTNCCNMGNCCNATHTGYYTNAGYCARACNGAR---ATGAARATHTAY AARTGYYTNYTNACNGGNGAYGARATGTTYAGYGAYACNTAYCCNGTNAARGARGARGAY GGNGTNTAYATHGTNAARGGNAARTAYGTNACN---MGNAARAGYGAYGAYGTNGAYGAY TCNAARATHGGNGGNAAYGCNAGYGCNGARGARGCNGCNGAR---GAYYTNGARAGYGGN ACNGARTCNGGNATHGAYGTNTGYYTNGAYAGYMGNYTNGTNGARACNTCNTTYGGNTCN AARAARGARTAYCARYTNTAYATGAARGGNTAYATHAARGARGTNYTNACNAARYTNGCN GARGGNGTNTCNGARGARGAYATHGCNAARYTNAARGAYGARACNACNACNAGYTTYAAR GCNATHTGYGCNAARTTYAARGARATGTCNTTYTTYACNGGNGCNAGYCARAAYAGYGAY GGNCAYATHGCNGTNGTNGAYTGGGTNGAYGARGARGTNGAYGGNAARACNGTNAGYTAY GCNTAYACNTAYTTYTAYAARATGGGNATGGTNGTNGARAARGGNGCNGTNGGNTGYMGN AGYCARAAYGARYTNATHGAYATHATGGARGARGTNAARTCNGGNAAYTTYACNATHGGN GARGCNGARATGYTNTTYAAYGCNTGGAARGAYMGNTAYCARMGNGGNAAYTTYGCNACN AGYTTYAARGAYAARCARGCNACNYTN---------------------ACNTAYMGNAAR TTYTAYGGNMGNMGNCCNGAYGGNYTNAAYGGNGCNATG--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CARACNATHGAYYTNAAYGGN GCNGAYTTYATGGARGTNAARCCNACNATGACNMGNAARYTNMGNMGNMGNCCNAAYGAY CCNATGCCNATHCCNGARAARMGNMGNAARCCNTCNCCNGCNCARGTNAAYATHYTNYTN GAYGAYGAYCAYATHYTNGCNGAYYTNMGNYTNATHATGAARGTNAGYGGNAARCCNYTN GCNAARAARCARGGNYTNGGNACNCAYAGYCCNATHGTNGAYACNTCNTCNGAYGTNMGN ATHGARGAYGGNMGNYTNTGGTAYGAYAARAARTGGTTYCARMGNAAYACNATGGTNCAR ATHGAYAAYAARGARACNGGNTCNMGNATHCAYGGNACNATHACNAAYATHYTNAAYCAR GARATHTGGGTNAARAARGGNGGNGAYAAYTCNAARYTNMGNATHTGYYTNAAYCARTTY CARAARGGNAARTAYGTNATGAARAARMGNACNTCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ACNATHTGYAARGAYTGG------------------------------ ------------------------------------------------------------ ---------------------------------ATGTCNMGNGCNGCNGTNTCNAARACN MGNGGNGCNGAYAARACNAARCCNCCNGCNTCNCARACNCCNGTNATHGCNCAYGARATH GTNCCNGGNAARTTYAAYGAYAAYGAYTGGAAYGTNATGGTNGARMGNGAYGGNGGNGAY GARTTYATHTTYGAYATHATGGAYGARYTNATGGARAARACNATGACNACNATHTAYGAY AARTAYATHGARMGNCARYTNYTNCCNTTYACNATHACNCARGCNMGNGAYGCNATHATH GARATHATHGARTGGCARTTYYTNACNMGNGAYGARGGNGARGARAAYYTNGARGCNGAY YTNGGNTGGACNCARGAYGARGARCCNGARCCNGCNGARACNGAYTGYTGGGCNCARGGN TCNGTNCCNAARAGYGTNATHYTNGCNCCNACNCCN------------GARYTNGARGAR ATHCCNGARGARGTNGCNGARGARYTNGCNCCNGARGARCAYAARGAR---GARACNCAR GARGAYGTNTCNCARGARCCNCCNGARYTNGARGAYGTNGTNTCNGARTCNGGNGARCCN ACN---------GGNACNACNACNGARCARAGYAARAARGGNAARGGNAARACNCCNGCN CCNCCNAARGCNTCNGTNGGNGGNMGNAARAARTTYMGNCCNTAYMGNGGNAARYTNAAR TCNGCNGGNGTNGGNAARATGACNGARTCNYTNGARGARACNGARATHAARATGATHTAY GAYGARATHGTNGCNTCNATGCCNCCNAGYGARGARAARCCNAGYACNYTNYTNAAYATG CCNGCNTCNTGYACNAGYATHYTNAARGTNCARACNGGNMGNCCNCCNGGNAAYAARGAY GTNGTNTAYGAYGAYYTNGGNAAYGTNGTNGCNGTNATGAARYTNGAYCCNGARAARYTN CCNACNCAYAARGTNAAYGTNAARTAYCAYGTNGTNGAYCCNGCNGTNGARGCNGCNCAR GCNMGNYTNGAYGCNATGMGNAARGGNAARTCNACNGGN---AARATGMGNAARCCNAAR TCNACNAARAAYYTNACNACNGAYTCNAAYCCNTCNACNTCNAARGCNMGNTAYTCNAAY ACNCARGGNGCNGTNGCNCCNYTNCCNCCNCCNYTNCCNCCNAGYGCN------------ ---GARYTNTCNGTNTCNGARGARATGCCNAARATHGARGARATGGARGTNTCNCAYGGN GTNATHGTNMGNGARGGNGGNMGNGTNAARAARGGNCCNGGNMGNTAYTAYMGNAARYTN GAYGTNYTNGARGARAAYCARAARGGNATGAARCCNGTNAGYATHMGNYTNAGYAGYACN GGNATHACNGTNAAYGAYYTNYTNGAYMGNAAYACNCCNATHYTNMGNCCNYTNGCNGAR CARTCNCCNYTNCCNCCNATHGTNCCNCARCCNCCNCCNCAYTCNCAR---CAR------ ATGGCNMGNATHTGYGTNATHGGNGCNGGNATHATGGGNTAYAGYGCNGCNGTNAAYGTN CARATGGCNYTNCCNGGNGCNAARGTNACNATHGTNGCNGAYGARTTYGGNCARCARYTN GTNACNTAYGGNGCNGGNGGNYTNTAYMGNCCNGAYYTNGARCAYYTNTGYAARGGNGGN AAYGAYGAYATGATGAARCARTGYATGMGNGAYTCNTGGGAYCAYTTYTCNMGNYTNGCN ACNTCNCCNYTNTCNGGNGARTCNGGNAAYTTYYTNGTNTCNGGNATGTTYTCNCAYMGN ATHCCNATGGAYGAYMGNTAYGCNATGATGMGNGARTGYACNTAYGAYTTYMGNMGNATG TCNGAYAGYGARGCNMGNCARMGNGGNATHCCNAAYGAYTTYAARTAYAAYTAYTTYTGY ACNACNGTNATHACNCARCCNTAYAARTAYGTNCCNTGGYTNAARAARCARTTYGARGCN AARGGNGGNMGNACNCAYACNMGNACNGTNMGNAAYYTNGARGARYTNCAYGGNGARTTY GAYYTNGTNATHAAYTGYTGYGGNATGMGNGCNYTNACNTTYYTNTTYGAYTCNCARTGY TTYCCNATHMGNGGNCARYTNGTNMGNGTNAARGCNCCNTGGTTYAARCAYTTYCAYTAY TTYGAYACNGAYACNTAYATHATHCCNCAYGARGAYAAYYTNAAYATHGGNGGNATHMGN ATHCAYGAYGAYGGNAAYACNGARGTNGAYCCNGARGTNACNAARACNATHATHAARAAY GCNGARGCNATGTAYCCNMGNYTNAARGGNGCNGARATHYTNAAYGCNTGGGCNGCNTCN MGNCCNGGNMGNAGYTCNCCNMGNATHGARYTNGARACNYTNAARYTNGGNCAYAAYAAR CARYTNCCNGTNATHCAYAAYTAYGGNCAYGGNGGNCAYGGNATHACNYTNAGYTGGGGN TGYGGNGTNCAYGTNGCNGGNATGGCNAARACNGCNYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNGCNACNTCNGCNTAYCARATHGARGGNGGNTGGAAYGCNGAYGGNAARGGN CCNAGYATHTGGGAYACNTTYGCNCAYAAYAAYMGNYTNGCNAGYAGYCARACNGGNGAY GTNGCNTGYGAYAGYTAYCAYYTNTAYATGGARGAYGTNAARATGYTNCARTCNYTNGGN GTNAAYTAYTAYMGNTTYTCNATHGCNTGGAGYMGNGTNATGAGYGAYGGNACNATGGCN ACNATHAAYCCNGCNGGNATHGAYTAYTAYAAYAARYTNATHGAYGCNYTNATHGCNGCN AAYATHATHCCNATGGTNACNYTNTAYCAYTGGGAYYTNCCNCARGCNATHGARGAYAAR GGNGGNTGGAARAAYGARTCNGTNGTNGCNYTNTTYGARAGYTAYGCNMGNATGTGYTAY GARCARTTYGGNGAYMGNGTNAARTAYTGGATHACNTTYAAYGARGCNTTYGTNGTNAGY TGGYTNGGNTAYGGNATHGGNGTNTTYGCNCCNGGNATHTAYGAYCCNGGNAAYGGNGTN TAYACNGTNGCNCAYAAYATHATHMGNTCNCAYAGYMGNGCNTAYCAYGTNTAYGAYCAR AAYTTYAARGCNMGNTAYGGNGGNATGGTNGGNATHACNYTNGAYATHGARTGGAARGAR CCNYTNACNGAYGCNCCNGARGAYGCNGAYGCNGCNGAYMGNGCNATHCARTTYAARYTN GGNTGGTTYGGNAAYCCNATGTAYGGNGGNACNGGNGAYTAYCCNCARGTNATGAARGAY TTYGTNGCNMGNAARAGYAARGARCARGGNYTNYTNAARTCNMGNYTNCCNGCNTTYACN GARCARGARAARAARYTNAAYAARGGNGCNTAYGAYTTYYTNGGNATGAAYCAYTAYACN ACNAAYYTNGTNGCNGAYCARCCNMGNCCNAAYAGYGAYCARAAYTAYGARCARGAYCAR GAYATHGAYACNAARGCNGAYCCNTGYTGGCCNGGNACNGARGCNAGYTGGYTNAARGTN AAYCCNTCNGGNATHMGNAAYATHGTNMGNTGGGCNMGNGAYCAYTTYAAYAAYCCNCCN ATHTTYATHACNGARAGYGGNMGNCCNGAYGGNGCNGAYYTNTCNGAYGAYGGNMGNATH TAYTAYTAYAARAAYTAYATHAAYGARATHYTNAARGCNATHMGNYTNGAYGGNGTNGAY GTNMGNGGNTAYACNGCNTGGTCNYTNATGGAYAAYYTNGARTGGACNAGYGGNTAYTAY TCNAARTTYGGNYTNTAYMGNGTNGAYTTYGAYCAYCCNAAYMGNACNMGNACNCCNMGN ACNTCNGCNGCNTTYTAYAARCARYTNATHAARGAYAAYGGNTTY------TGGMGNATH GCNAAYTTYATHATGGCNGCNTTYTTYTTYYTNGCNGGNATGGCNAAYACNAAYGAYAAY GAYTGGTAYATHTGGACNCCNATHTAYTTYTAYGCNTCNGGNYTNTGYYTNGCNGCNTGY GTNTTYTCNTCNGTNGTNAAYAAYGCNYTNTGGCARGTNTGYATGTGGGTNCARATGGGN GTNGCNATHGTNATGGGNGTNTAYCARGTNGCNYTNYTNTGYACNGTNTCNCAYAARATG GAYACNAAYCCNYTNGCNCAYGARGARGGNMGNGARATGGGNGGNYTNYTNATHATHYTN GCNTGGACNGGNATHACNMGNTTYTCNCCNTTYGGNAGYTCNAARCCNGGNGGNCCNTTY ACNYTNATGACNGGNYTNYTNGTNGTNTCNYTNACNYTNGCNGTNGTNCCNYTNGTNACN TGGTCNYTNTGYTTYGTNAGYGAYTGGCAYMGNTAYYTNGGNCAYTGYTCNGGNATGTTY ---------------------------------------------------MGNACNGCN CAYAAYGTNGAYAARCCNTAYAARTGYACNGTNTGYGAYAARGCNTAYAGYMGNAARGAY ATHYTNCARGAYCAYATGMGNGCNCAYGAYGARAAYAAYCCNAAYAARTGYACNGTNTGY CAYAARGCNTTYMGNAAYAGYTCNACNGTNCARCARCAYATG------------------ ------------------------------------------------------------ ---MGNATHGTNCAYGAYGGNGARAARGCNTAYYTNTGYGCNTTYTGYGGNAARMGNTTY AGYAAYTGYAGYAGYYTNAARAAYCAYGGNAGYGTNCAYGAYACNGAYAARCCNTAYAAR TGYACNGTNTGYTTYAARTCNYTNAGYAGYMGNMGNAGYYTNYTNACNCAYACNMGNATH CAYGGNAAYGAYAARCCNTTYAARTGYTCNTTYTGYTGYAARGGNTTYGAYCARAAYGGN AGYYTNCARMGNCAYATHAARGGNCAYGARGGNGAYAARCCNTAYAARTGYACNYTNTGY TCNAARGGNTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYTTYMGNMGNATHAARMGN CCNCAYGCNGAYAGYGAYAGYGAYGAYGARTTYGGNAARGGNAGYGGNATHAARGTNGAY AARACNAARYTNCARAARYTNAARGARATGTTYCCNGARGGNGAYYTNAARMGNATGAAR GCNGCNYTNTTYGCNTAYGAYAARGAYTTYTCNAARGCNATHGARTTYATGAARGGNGGN GAYAARAARAARMGNCCNATHTCNTCNGAYCARTCNGAYGARYTNCCNGARATHACNGGN AGYMGNAARMGNATHAARGTNATGCCNGAYACNCCNTCNCCNACNAARGARAGYGGNTTY TCNYTNTCNACNTCNACNGGNGTNGAYCARAARTCNGTNAAYTTYYTNAARGARTGYTTY CCNGGNAARTCNGTNGARCAYATHCARMGNATHYTNAARGARAAYGAYGGNTCNACNGAR MGNGCNTCNGTNGCNYTNACNAAYGARGGNAGYGGNGAYGCNAARGCNGARTCNYTNGCN TCNTCNGGNAARGCNMGNCARTCNGGNYTNATGAARGCNGTNAARGARCARAARGCNAAR ACN------AAYGCNAARCARAARAARGAYGAYATHAGYGAYGAYGARGAYGARTAYGGN GAYGARGARTAYAGYGGNGAYAGYGARGAYAGYGARGAYYTNGAYAAYAARACNAARTCN GARATHGAYAAYTTYYTNCARTTYTTYGARGARGCNACNGTNGAYGARYTNTCNGCNATG CCNGGNTGYTCNAARAARAARGCNGARATHATHCARACNYTNMGNCCNTTYGARTCNTGG GAYGAYYTNTGYATHAARTTYGAYAAYACNAARCCNYTNTCNACNGCNYTNATHTCNGGN TGYAARGARATHATGMGNGTNMGNAAYATHATHMGNMGNYTNATGGTNMGNTGYGARAGY ATGTCNCARCARATGGARAARGTNGTNTCNACNYTNACNMGNGAYAGYCARCARAAYAGY GTNCAYGAYAAYGGNMGNATHGCNMGNCARCCNGARYTNYTNAAYAARGARTTYTCNYTN AARCCNTAYCARYTNATHGGNYTNAGYTGGYTNMGNYTNATGCAYGARCARGARYTNAAY GGNATHYTNGCNGAYGARATGGGNYTNGGNAARACNATHCARGCNATHTCNTTYYTNGCN CAYYTNYTNGAYGARGAYGARGCNGGNCCNCAYGTNATHATHGTNCCNTCNTCNACNATH GARAAYTGGYTNMGNGARYTNCARACNTGGTGYCCNGCNYTNAARGTNATHGTNTAYTAY GGNTCNCARGARGARMGNMGNGCNGTNMGNCAYTCNATHTTYGTNCARGARGARGAYTTY AAYGTNYTNYTNACNACNTAYAAYATGGCNACNGGNGGNGTNGARGAYMGNGTNYTNTTY AARAARTTYGARTTYCAYTAYGCNATHTTYGAYGARGGNCAYATGYTNAARAAYATGTCN TCNYTNMGNTTYCARAAYYTNATGAARATHGTNGCNGARMGNMGNYTNYTNYTNACNGGN ACNCCNYTNCARAAYAAYYTNYTNGARYTNATGTCNYTNYTNTGYTTYGTNATGCCNGAR ATHTTYCARGGNAARACNGAYTCNYTNAARAARATGTTYACNATGATHTCNAARTCNGAR GAYAARCARAARAGYMGNTTYGARTCNGARMGNATHGCNCARGCNAARMGNATHATGAAR CCNTTYGTNYTNMGNMGNYTNAARAARGAYGTNYTNAAYCARYTNCCNAARAARATHGAR AARATHGTNMGNTGYCARYTNACNAARTCNCARMGNACNYTNTAYGAYGGNYTNGTNTCN MGNTAYGCNCARGARGTNACNGCNGARGAYGAYGGNACNACNGCNAGYGGNGCNGGNATH TTYATGCARTTYMGNAARGCNGCNAAYCAYCCNYTNYTNYTNMGNAAYYTNTAYACNGAY AARYTNYTNGARCARATGGCNAARAARATHTCNAARGARCCNTCNCAYMGNGAYMGNGGN GCNYTNCCNAARYTNATHCARGARGAYATGACNTAYATGAAYGAYTTYGAYYTNATHGGN YTNTGYMGNCARTAYAARAARTAYYTNGGNAARTTYGARYTNGAYGGNTCNGTNATHGAR GAYTCNGGNAARTTYCARAARYTNGAYGARYTNYTNCCNGAYATGAARGARAARGGNGAY MGNGTNYTNYTNTTYAGYCARTTYACNATGATGYTNGAYGTNATGGARCAYTAYYTNGAR AARMGNCARCAYAARTTYATHMGNYTNGAYGGNCARACNCCNGTNCCNGAYMGNYTNCAR YTNATHGAYMGNTTYAAYAAYGARCCNGAYATHTTYATHTTYYTNYTNTCNACNMGNGCN GGNGGNYTNGGNATHAAYYTNGTNACNGCNAAYACNATHATHYTNCAYGAYATHGAYTTY AAYCCNTAYAAYGAYAARCARGCNGARGAYMGNTGYCAYMGNYTNGGNCARAARMGNGAR GTNACNGTNATHMGNYTNATHAGYGARGAYACNGTNGAYGARTCNATGYTNMGNTGYGCN AAYAAYAARYTNGCNYTNGARAARGAYYTNACNGGNCCNGARGGNGARGARGARAGYGAR GCNGGNAARGAYGTNGCNAAYYTNYTNAARGARGTNYTNAARCARMGNCAR--------- ------------------------------------------------------------ ---------------------------------------------------YTNMGNAAY AAR------YTNATHTCNATGAGYTGGCCNMGNATGTAYGTNGTNGTNGCNAAYCARTGY ATGTAYTAYTTYTCNAAYGARACNTCNMGNAARGCNGCNGGNTCNGTNTCNYTNTAYGGN TTYAAYMGNATHTGYMGNGCNCCNACNGCNAARGCNGGNGAYGCNGTNTGGGCNTTYAAR YTNGARCAYATHCARCCNAAYTTYMGNTCNYTNTAYTTYTCNGCNCCNTCNGARAGYGAR ATGGTNAARTGGATGMGNGTNATHAARMGNGARATGYTNACNGCNAAYGGNAARAGYACN AGYTGYTCNGCNGGNGAYTCNCARTAYGGNGARTCNATHGCNTCNGARGAYTCNTGGGGN TCNTCNGAYTAYAAYTTYYTNGARACNAGYATHTAYGARGARCCNTGYGCN---MGNCCN YTNTCNACNATHGCNAAYACNGAYGGNAGYAARGAYGAYAGYGAYTTY---GAYTGYGAR GARGTNACNTCNGCNAAYCARTTYGAYCARMGNYTNACNCCNGCNCCN------------ ------GTNTAYGAYACNGGNTAYAGYGTNGARAARAGYGTNTCNCCNGARCCNTCNAAY CCNCAYAGYGAY---TAYTGGTCNGCNGTNMGNTTYGAYGGNACNAARYTNCARGCNTCN GARATHATHGGNCARYTNGCNCARGAYGGNGTNTAYYTNGTNMGNAARAGYGARGAYAAY TCNAAYGTNYTNGTNGTNCAYGCNGGN---GTNAARAARTAYAARGTNYTNGAYCARGCN AAYGGNAARATGACNYTNTCNGCNACNGARCCNGAYTTYGAYACNYTNGARGAYATGYTN TAYCAYTAYTAYAGYAAYAAYYTNCCNCAYAGYAGYCARAARYTNATHMGNCCNTTYAAR YTNCAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGGCNGAYTCNAARTCN AGYYTNGCNMGNGAYGGNACNATGCARGTNACNGCNAARGARGGNATHGAYTAYYTNAAR TCNGCNCAYAARGAYACNYTNYTNAARGTNCARGGNYTNGTNAARGAYAARCCNGCNGTN CARMGNGAYGGNACNATGGTNTCNACNGCNAARGARGCNGAYMGNATHYTNGAYGGNAAY AARCCNGAYGCNGAYGCNCARACNMGNGGNCARCARAARCARATHGAYGAYYTNAARAAY GCN---GARCCNCCNAARGCNAARAARGCNMGNYTNGCNAARGAYGGNACNATGGCNGTN ACNGCNAARGARGCNAARGGNATHYTNGCNGGNGARAARYTNGGNGAYACNMGNCARGAR ACNAARAGYAARGCNGGN------AARACNCCNYTNMGNAARGCNAAYACNATGGCNMGN ACNGTNGARGARGCNAARAGYGTNYTNGAYGGNAARGTNGAYYTNAGYGARGGNMGNAAR ACNMGNTCNCARAGYMGNGGNGARGTNCCNAARCCNTCNATHAARAARATGGGNACNATG CARCARACNGCNAARGAYGGNAARGCNTTYYTNAARAARAAYAARGGNAARAAR------ ---MGNGCNGCNAARGCNGAYGAYGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CARMGN GGNGTNTCNCCNCARMGNCARAGYGGNYTNCCNCARGCNMGNMGNCARATHGCNMGNCCN TCNACNGCNCCNMGNTCNTCNYTNCCNCARTTYMGNMGNCCNGTNACNCCNTCNACNMGN ACNGGNACNGCNCARGAYGARGCNAGYTGGMGNGAYGGNTGYTTYATGCCNAGYTTYCCN ---YTNGTNAAR------------------CAYACNATGGCNGCNGTNGGNGCNAAYACN ACN------------MGNATGATGAARCCNCAYGTNCCNATGATHMGNTTYCCNAARMGN GARCCNYTNAGYGARATHAARATHGGNACNGGNACN---GGNAAYCCNAAYTCNYTNGAR GCNYTNATHACNAAYACNGCNCCNTCNAARCCNACNTCNGCNACNGTNGGNGCNAARAAR CCNAARGGNCCNTCNGTNGAYTCNTCNGARYTNCCNYTNMGNTTYMGNMGNAARYTNATH TCNAGYGARGARATGGARTTYATHGARAARGGNGGNCCNGTNTTYGCNGCNACNGTNTTY YTNATHGTNGCNGCNMGNGCNYTNAGYCCNGTNGARGCN------------GGNGCNTGY GTNGARGARTGYAAYGTN---GAYGGNGGNYTNTTYAGYGAYGGNTGYCCNGAYGGNCAY GTNTGYTCNTAYAAYGGNTGYGGNCAYACNTGYMGNCCNGTNAARMGNGAR--------- ---------AARTGYCCNGGNGTNTTYTGYTTYATGTAYTGYAARCAYGGNTGGGCNAAR GGNGAYGAYGGNTGYGARATHTGYGARTGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNAARGTNTCNAAYGARGTN CAYCAYGTNTCNATHMGNMGNGGNATHCARGCNYTNMGNYTNAAYAAYTTYAAYCCNAAY GCNYTNMGNMGNMGNCCNGTNCCNGARGARCARAARMGNATGGARTCNATHCCNGGNGAY GTNYTNYTNTGGACNAAYCAYMGNGTNATGGARTGGYTNMGNACNATHGAYYTNTCNGAR TAYGCNCCNAAYYTNMGNGGNAGYGGNGTNCAYGGNGCNYTNATGGTNYTNGARCCNMGN TTYAAYGCNGARYTNTTYGCNGTNYTNYTNTCNATHCCNTCNAGYAARACNYTNYTNMGN MGNCAYYTNAGYTCNCAYTTYATHGGNYTNATHGGNAGYGARACNCARCARMGNAARMGN GARTGYGARTCNCARACNGGNTTYATHCCNYTNACNCAYAAYAAYAARATHAARAARGGN AARTTYGGNYTNTTYAAYCAYAARMGNAGYMGNTCNGARCCNGARATGGAYAGYYTNATH TGYCCNCCNGAYYTNAAYGGNCAYTCNAARTTYCAYACNCARGCNTCNCCNYTNYTNTTY MGNYTNTCNGARAAYYTNTGGGGNGARCCNATGAARAARMGNAARTCNGTNGAYCCNCAR GCNGCNYTNGCNMGNACNCARAARMGNYTNAARAARATHGAYAARGARATHAARMGNYTN TCNMGNTTYGGNMGNATHYTNAARCCNGTNGAYGARATHGARGTNGAYMGNMGNAARYTN ATGTCNGCNGTNGARMGNMGNMGNGARTCNACNGTNYTNACNTTYGARGARTCNGARTCN MGNGCNYTNYTNCAYAARGARTGGGCNTGGAAYMGNACNAARMGNCAYTAYGARMGNACN MGNYTNTTYTCNATGGCNTCNGCNGCNCARCARGARGCNYTNGAYGARYTNMGNYTNGAR TCNGARGARYTNTAYCARGCNGCNATHCARAARGAYGARAGYYTNYTNCCNYTNTCNTTY GARGGNCCNAARGARACNCCNCCNATHAARGAYTAYAGYCCNCCNGAYGGNGARTAYATH GAYACNACNMGNAARTTY---------AGYGGNGAYGCNGARTGGAAYATHGAYATGGAR GTNAAYYTNTTYCAYGCNATGMGNGGNCAYAARCCNGCNGGNGTNAAYMGNCAYTTYCAR ATGATHGCNATHCAYGAYAARYTNAGYTCNTCNACNAARAARGTNACNTCNGGNGAYGTN TGGAARCAYYTNTCNACNYTNTAYGAYYTNCARGCNYTNTAYGARTCNGARATHGTNCCN TTYCCNAAYAARAAYGGNGAYTTYGCNYTNGTNGAYMGNGARATGYTNGAYATGTGYACN AARTCNTTYCCNMGNTCNACNTTYATHAAYAGYGTNCCNAAYGARCAYGCNAARGCNGAR GCNCCNGGNAARAGYATHTCNAARTTYAGYACNAARCARGARAGYAARTCNGGNTCNCAR ACNCCNAARACNGARGTNAARAGYGARCAYAAR---TCNACNAGYGCNTCNAARGCNGAY AGYMGNTCNAGYACNCCNGCNGGNMGNTCNGAYTCNAARTCNTCNCAR------------ ------------GGNAGYAGYTCNAARTCNTCNCAYCCNGGNACNCCNACNTCNATHCCN TCNCCNTCNCCNAARMGNACNAARMGNACNMGNAAYGTNAAYTCNGCNTCNGCNAGYCCN GCNACNCCNACNGARCCNCARTCNAARMGNMGNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GARCCNCARTGGGTNGCNGTNAGYGARCAR GCNAARGAYYTNYTNMGNGARATHYTNACNCARGAYCCNGCNCAYMGNATHTCNTCNGGN GARGTNYTNAAYCAYGARTGGTTYACNGGNAARAARMGNGARCAYCCNAAYGTNYTNAAR ATGATGAARGARTTYMGNMGNGARCARGARGAR---GARMGNACNGCNMGNATHGAYGAR AAYACNAAYAGYGCNATHAAYGGNGTNCARGCNGGNGARGCNACNCCNGAYGGNCCNGCN CCNACNACNAAYGGNAGYGGNAARAARMGNAARGGNTCNGGNGGNAARAARAGYACNAGY GGNGAYMGNAGYAGYCAYACNCCNCCNAGYTCNAGYAARCCNTCNCARACNACN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNAARCARCARTTYCARCARYTNCARGARCARCAR CARCARAARYTNYTNGARMGNMGNAARMGNMGNGARGARAARAARAAYAARAARGGNAAR GARGARAARGAYAGYGGNTCNGAYAGYTTYAARGTNCARGAYGAYYTNAAYYTNAARYTN GCNGAYCAYTCNAGYAARGGNTAYGGNTAYGTNTCNGARGARYTNGTNGAYCAYYTNAAY GAYCARATHMGNCARYTNAARGAYGARAAYGGNMGNYTNTAYAARYTNYTNAGYGARAAR GAYTTYGARATHMGNCARTAYAARAARAARAARGARGAYCARTCNCCNGAYACNATGGAY YTNTCNGTNACNAAYGARGCNGCNGCNACNAARATHGTNCARYTNAGYAARMGNGTNMGN GARYTNACNTCNGARAARGARTCNGARAARACNMGNTGYAARCARTTYCARAARAARTGY CAYGAYYTNCARYTNCARYTNCARTCNCARCCNCCNACNCARGAYAAYTCNTCNGTNATG GGNTCNATGGTNAGYYTNMGNAGYATHMGNTCNAAYMGNGARGAYGAYGGNGTNGAYGTN AARGCNYTNCARGAYMGNYTNAARCARTCNGARGCNMGNYTNTCNGAYTTYMGNAAYCAR TGYCARCARYTNMGNCARGARYTNAARGTNGCNCAYAARGTNYTNTCNCARGARATHGGN GARACNGTNAAYATHCARTCNYTNYTNAAYGARACNAGYCARTGGMGNGGNMGNGCNCAR CARATHATHGCNYTNCARCARAARYTNGARGARATGAARGTNAARTAYGARGGNCCNCCN GGNATHGARATGYTNGGNGGNGCNGAYAARGTNACNACNGCNMGNMGNMGNCARGARGAR MGNTAYMGNGARGARYTNMGNMGNACNGARAARGARMGNAARGARGCNYTNGARGTNTCN ATGAAYAARYTNMGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TGYCARTCNYTN YTNYTNTCNTAYGAYTAYGAYTTYTGYYTNCCNGTNGTNGTNGAYAARGAYCARGAYGAR TTYACNGTNGAYAGYGGNTGGATHGCNGGNGCNTTYTTYYTNGGNYTNYTNYTNGGNATH GGNYTNGTNYTNYTNYTNGCNMGNCCNTTYYTNAARTCNTGGGARAARAARAARCARCAR GAYGARGARTAYATGYTNGAR---AAYACNGTNAARGCNGAYGARGCNGTNCAYGTNAAR AARGAYAARGAYGARAARCARGARAARAARGGNMGNMGNAARTCNAARGCNGGNAARCAR GARGGNGTNATHMGNGGNAARTCNMGNTTYTGGMGNMGNAARAARGGNAGYGGNAARGAR GAYGARCARGTNAARGARGGNGAYATHGAYCCNGCNCAYGCNMGNGGNATGGTNGAYGTN ATGYTNCARACNTCNAGYACNGGNGARGARGTNGARATGGCNGAYCARGAYATGGCNTCN ATHATHTCNATGGARMGNAGYYTNGARGARGARAARACNACNATGATGYTNAARACNYTN GCNATHYTNYTNMGNAARAARGCNGARAARMGNGARATHACNCARAAYTTYTAYAAYGAY TTYYTNAARAARACNGARGARGAYYTNAARGAYATGGGNACNATGATHGAYMGNGARAAR GARGARGCNGARGARAARYTNAARAAYGAYCCNAARYTNAAYAARGAYACNCARGCNYTN GARACNGARATGCARAARYTNCARACNCARTTYAAYCAYAARCARGCNAARYTNCARAAR GAYTTYMGNGAYAARATHMGNYTNGAYYTNYTNMGNTCNTCNGGNATGCCNGARTCNGAR GTNGARGARGTNATHTCNGGNYTNATGGCNAAYATGGCNAARGTNGARGARAARYTNGGN YTNGARCARGCNMGNCARMGNMGNAAYYTNGARCARMGNYTNGCNAARMGNMGNCARGCN ATGGARTAYCARCARGTNGARAARGARGAYAARATGMGNGARCARGARGCNAARGTNAAR YTNTTYMGNTCNYTNYTNGARCARCAYACNAARGARGGNTCNYTNYTNGARCARCARTGY GAYACNATHGTNAAYGAYTAYGARAAYGARYTNGAYACNYTNMGNAARTAYCAYGCNGGN GARTTYAAYCARYTNMGNYTNGAYAARTTYGARYTNYTNCARCARGAYMGNYTNAAYAGY TTYCAYAARYTNAAYAARAARCAYGAYAARGARAARGCNGCNTTYYTNCAYAGYGCNGAY AARGCNACNAAYCCNTCNGARTTYATHAARGTNTAYCAYGAYYTNYTNACNAARCARCAY ATGGARAARGARGCNYTNTCNGGNGARYTNGAYATGMGNGARATHCARGARATHCAYAAR YTNAARGAYGARAGYGCNAARAARGARGCNAARGCNGCNAGYCARGTNACNGAYAARYTN GCNGARCARATHGARGGNTCNTCNAAYATHACNTCNAARGARGCNGCNAARGTNGTNAAR ATHCAYAARGCNGARATGGARCARTTYMGNGCNAARCARCARMGNGAYAARCARGCNATG YTNGCNMGNYTNCARGARAARYTNCARCARMGNATHGARGCNGCNGAYGARGCNGARGCN MGNGAYCARAARGARCARGARCARYTNAARGARCARCARATGGCNACNYTNGAYAARGTN YTNGCNTCNAAYYTNGAYYTNTCNGAYGARGCNAARGARMGNATHATGMGNGARCAYGAR CARAAYATGCARACNYTNTCNAAYCARYTNATGMGNAGYAARATHMGNCARCARAARAGY YTNGARATHAARYTNAAYCARMGNAARGCNAARYTNGCNGARYTNAARCARAARMGNGAR CARYTNTCNGARGCNMGNCCNGGNAGYAGYAARAARGARAARGCNAAYATHGARACNAGY ------YTNGAYGARCARATHGCNAARGARGARGCNAGYTTYGARGAYGCNMGNCARTCN GCNGTNGCNGAYYTNMGNAARCARYTNGCNYTNGARACNGARGARGCNYTNAARCARCAR GAYGARGARATHGGNYTNYTNATHGGNMGNYTNCARGTNGGNCARGCNMGNMGNAARGCN ATHATHGARAARCARGAYGCNGTNYTNAARGAYYTNCARGAYAAYYTNGARMGNCARGTN ACNTCNGCNAGYGGNYTNMGNCCNTCNATGACNGAYCARATHYTNAAYCAYCAYTAYGCN AARGTNTCNCAYYTNAAYGAYCARYTNCARMGNCAYMGNGAYGAYCAYGARMGNMGNATH YTNGARAARYTNTCNCARAARMGNGCNGARAARGARTAYCARATHGARTCNCARYTNGAR CARGARGCNCAYTCNGARTAYTCNGARAARCARAARMGNGGNGCNGGNTAYGCNAGYYTN GCNYTNATGCARTCNTTYYTNGARCARMGNCAYGCNAARGCNYTNCARGARYTNGARYTN GARATGAARGCNGARYTNGARAARAGYMGNAAYGARYTNAAYCARCARYTNGARGTNGAR YTNMGNAARGARYTNGAYGCNGARMGNCARAAYYTNYTNACNCARYTNGCNGCNGTNAGY GAYATHTCNCARAGYGAYYTNCARAAYGCNGTNACNGCNGCNACNAARGGNCARACNGAY TCNAARGTNGCNAARMGNYTNGCNAARGAYYTNAARGAYAAYGTNGARMGNGCNMGNTCN GCNATGTCNGTNCAYMGNGAYGAYCCNMGNGAYGAYGAYATGGGNTTYMGNMGNACNMGN ACNGAYYTNGARGAYAARMGNCARTTYACNGGN---------MGNAARGGNTCNGCNGTN TCNGTNCARMGNMGNGGNAGYGCNMGNCARGCNTTYGCNGAYGARGAYGAYGAYGAY--- ATGGAYATHYTNTAYATHTCNGTNTGYTTYATHGCNYTNTTYGGNATHTGYTTYGGNCAR GAY------CCNYTNGARGTNAGYTTYGARAAYGCNACNMGNGTNGAYGCNATGGARGGN ACNAARGGNGTNCAYTTYMGNTGYCAYYTNAAYMGNGAYGCNATGTAYGTNATHAAYAAY ATGGTNGAYATHGTNCAYGTNCAYCCNYTNACNAARGARGARACNATHATGAGYTCNGCN GCNAAYYTNATH------------------GARGGNGARCCNCARTAYTAYGARGTN--- AARATGGCNCAYCCNGAYGAYTCNGAYTCNATGGTNYTNGAYTTYACNATHAARGARGTN MGNTAYTCNGAYGAYGGNACNTAYAARTGYCAYGCNCAYCCNGGNGGNAARTCNGAYTCN ACNGARGARGGNTTYGCNGARMGNGARATHGTNGTNCAYMGNCCNGTNACNACNYTNAAR ATGAARYTNGGNGAYTTYGAYGCNATH------------------GARACNTCNCCNYTN CAR---ATHGAYCAYGGNGARTAYAARGTNGTNTGYATGGCNGARGGNAGYAAYCCNGCN ACNGARGAYGTNCAYYTNTCNTTYCAYGGNYTNATGYTNGARCAYTCNGCN---CCNACN TTYACNCCNATGGGNGGNTCNGAYMGNCARTTYAARACNGARATHGAYGCNAGYYTNAAR ATHATGAAYGAYAAYACNGGNCARGARYTNGTNTGYCARTCNAAR------GAYTCNACN GGNCARTCNAARTCNGTNAARYTNACNATHAAYGTNAAYACNTAYGAYCCNYTNGTNTCN TGYAAYGAYACNGARGCNCAYGTNGGNCARGCNAAYCCNACNATHTAYTGYACNGTNAAY TAYACNGGNYTNGAYGTNGARGGNTAYGCNTAYCARATGGGNGAYACNGGNGAYACNGTN ---GARGCNGGNGAYAARMGNYTNGAYAAYATHGTNGTNACNGTNCARGAY------GTN TCNCCNGGNATHTCNGTNGTNTCNYTNGAYYTNCAYAARGCNGARCARCARTAYYTNGAY AARAAYTAYTAYYTNYTNATHGAYATGAARGGNGGNCAYACNAGYAARGARACNGTNMGN YTNAGYAARAARGARGGN---------------GGNCAYGCNAGYGGNAGYGGNGCNGGN AGYGARGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TTYYTNAGYGTNACNATHGAYTCNAAYATGGTNMGNAARAARTTYYTNGGNTTYGAY TTYGGNTCNCARAARYTNCARAAYATGGCNAARGCNYTNATGCCNTGYGGNTTYMGNYTN GGNGGNACNAAYGCNGAYTTYYTNACNTTYAARCCNGAYGGNGARGARTCNTCNACNACN GAYTCNGAYGAYGTN---------------------GTNYTNGARCAYAARMGNTCNCAY CAYAARAARTTYGGNAARCCNMGNCCNYTNACNAAYTTYACNATGTCNGGNGARYTNTGG GAYAGYATGATGACNTTYTTYGAYCARGTNGGNTGGTCNGTNATGTTYGAYTTYAGYYTN TTY---TGGAARAAYGGNTTYTGGGAYCCNACNAAYGCNGARGARYTNYTNAARTAYTCN TCNAARAARGGNTAYGARYTNGAYGCNTTYCARYTNGGNAAYGARCCNGAYATHTAYCAY GGNMGNTTYAAYATHACNGTNTCNCCNGCNACNYTNGTNAARGAYYTNACNATHYTNAAR GARGTNYTNCARMGNTAYCCNAARTAYTCNAARAGYAARYTNTTYGCNCCNGAYGCNACN MGNYTNGCNGGNMGN---ACNCCNCARCARTAYATHMGNGGNTTYATHGCNGCNGGNGGN AARCARYTNGTNGAYGCNATHACNTTYCAYCAYTAYTAYAARAARGGNACNGAYGCNACN ATHGARGAYTTYTAYAAYGTNAAYYTNATGGAYACNTTYAARGARAGYATHGARATHGGN GARGGNYTNGTNAARGGNACNCCNATHTGYYTNGCNGARACNTCNTCNTGYTAYCAYGGN GGNGCNAARGGNYTNTCNGAYGCNTAYGTNGCNGGNTTYYTNTGGYTNGAYAARYTNGGN YTNGCNGCNCARAARGGNGTNACNMGNGTNTAYMGNCARACNTTYTAYGGNGGNAAYTAY GCNYTNYTNTCNCCNACNYTNGAYCCNAAYCCNGAYTAYTAYYTNTCNGTNYTNCAYAAR MGNYTNGTNTCNGGNCCNGTNYTNAAYGTNACNGTNCAYCCNMGNYTNCCNGCNYTNMGN ATGTAYGCNCAYTGY---ACNMGNGCNTTYGGNACNTAYAARACNGGNGCNYTNACNYTN GCNTAYYTNAAYACNAARAAYGARGCNYTNTCNATHAGYGTNAGYCARTTYTCNTCNYTN CCNGTNGAYYTNTAYATHYTNACNCCNGGNGAYTCNGCNGGNYTNMGNTCNAARYTNGTN AARYTNAAYGGNGARGTNYTNAARATGTCNGGNTCNTCNGTNCCNGAYATGACNCCNAAR TCNCAYGARGGNGAYATHAARYTNCCNGCNMGNTCNTTYGGNTTYATHGTNGTNCCNGAY GCNAAYATHGCNGCNTGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GGNCCNAARATHGCNCCNCCNYTN---------------------CCNCCNYTNGCN ATGGGNCCNMGNCCNGTNMGNCCN------GGNGGNCCNYTNGCNCCNCARCCNGCNGGN CCNCCNCCNGGNGCN--------------------------------------------- AARATHTCNGAYCCNYTNAGYGAYCCNMGNTGGTCNGCNATGAARGGNYTNYTNGAYGCN GGNGGNAAYGARGARGTNGTNYTNGAYGAYAARCCNTTYGARYTNMGNATGGGNACNGCN MGNAARYTNCARGTNTTYGGNCARGTNTTYGARGTNMGNGTNGAYYTNAARGARMGNGGN ATHTGYATHAAYGGNCARYTNCARTAYAARYTNGGNGARCCNATHAARGARGTNAAYATH AAYGGNMGNATHGTNMGNYTNTAYTAYCAYGGNYTNCCNAARCCNATHTGGYTNGAYGGN CARTAYCAYGARATGMGNGTNGAYGCNCCNCCNMGNAAYGTNYTNATHGAYGGNTGYATG MGNGGNTTYCARATHGAYGGNMGNGAYAAYATGATHYTNGTNGAYMGNATHGARAARGGN CCNTAYGGNGGNCCNCCNMGNAARATHCARATHGTNGGNGTNGARCAYGARATHAGYTTY CAYTTYCCNCCNMGNACNATHYTNATHGAYGGNAARCCNTGYGARYTNAARYTNGAYAGY AARATHCCNTAYGTNATHATHGARGGNAARCCNCAYGGNATHMGNTTYGARGGNGARCCN MGNATHATHTTYATHAAYAAYCARCCNTTYACNATHCCNYTNGAYMGNGCNGARAARATH MGNATHGGNCARMGNCCNACNTAYATHGCNTTYGGNGGNCCNGCNCAYGARATHATHATH GAYGGNAARTGGTTYGARGTNAARTTYGAYAAYACNGTNAARGAYATHCAYYTNMGNAAY MGNCAYTTYAGYATHMGNATHCCNGGNCCNYTNCCNMGNGTNAARATHYTNGAYCARYTN CCNATGAAYTTYGAYGTNTCNMGNYTNATGATHAARAAYTCNGTNGAYGTNCARMGNGTN ATGCCNTCNACNGCNATGCARCCNGGNATHCCNAAYGCNMGNATGCCNGGNCARAAYCCN ATGGTNCCNGGNCARTTYAAYGTNGAYCARGTNMGNATGCCNMGNGCN------------ ------------------------------------------------------------ ------------------------------------------------------CARATH YTNCARCCNATGCARCARMGNCARCCNGGNCARGCNGCNCCNMGNCCNCARYTNCCNCAR GGN---ATHGTNCCNGGNYTNGGNGGNGCNCAYCCNGGNGTNATHCARCAYCARCARCCN ACNGTN------------CCNGGNGTNATHMGNCCNCARCARCARCCNTTYACNTCNYTN CARCARGGNATHTCN------------------AAYCARGTNCCNAAYATGTCNGCNAAY GGNCARTCNYTNGGNYTNTCNGGNCCNGGN---------------------GTNMGNAGY GARGTNCCNAAYACNCARCARCARCCNCCNGTNCARGGNGCNGCNATGGAYGCNAGYGCN YTNATH---------------------------------MGNGCNGTNYTNTCNGCNACN GGNAGYTCNACNGCNCCNGCNAAYCCNYTNGTNGGNGTNCCNCCNCARACNACNYTNGCN YTNCCNTCNACNACNGCNACNGARATGCCN------------------------------ ------------------CCNCCNCCNGCNGGNYTNTCN--------------------- ---------------------------------------------------------YTN CCNAGY---------------------------TCNGCNGCNTCNCCNTCNCARACNAAY ACNAGYACNACNACNTCNAAYCCNATGGAYATHAAYAGYYTNYTNAAYAAYYTNATGAAR GTNGGNYTNATHAARAARGARGGNAARACNGARGAY---AGYGCNCCNGTNCCNGTNCCN GTNCCNGTNTCNGCNCCNACNCCNGCNCCNGARACNCCNCARCCNACNTCNACNGARGAY CCNTTYCCNGTNAARAARAARGCNMGNYTNCCNGAYYTNTCNGAYTTYGAYGCNGAYYTN YTNAARATHTCNTAYCARMGNGTNGTNGAYGARYTNCAYGARGGNATHCARTGYCAYACN TGYTCNGCNMGNTTYACNGAYGARGAYCARGTNAARTAYMGNGCNCAYYTNGAYTGGCAY TTYMGNCARAAYAARYTNGARCARGARATGGTNAARGTNGCNAARAAYMGNAARTGGTTY TAYACNATHCCNGAYTGGATHCARTAYGARGARYTNGARGARAAYGAYGARAARTTYMGN AGYGARATHTTYGARCARATGMGNYTNGGN---AAYGARCARTCNGGNCCNGGNGGNATG YTNGAYGCNCARCARYTNMGNGCNYTNGARGGNAARGAYGTNGTNACNAAYCCNGTNGCN ACNGGNGTNGARGGNGARGAYGTNTGYGCNACNTGYGGNGAYTCNTTYGARTCNGTNTGG AAYGARGARACNGARGARTGGATHYTNAARAAYACNATHAARGTNAAYGGNAARACNTAY CAYCCNATHTGYTTYGARGAYATGCARGARACNCCNACNCCNGCNGCNGAYGTNATHMGN AAYCCNYTNGARYTNGARYTNCARCARAARCARCCNGGNATHAAYGCNGAYGTNAARAAY ACNGTNAARCCNGAYATHAARGCNATHAARATGGARCCNGGNTCNTCNACNYTNTCNGAR CCNGTNGARAAYCCNGAYTAYGGNGTNCCNTCNAAYCCNTTYATHAARACNGARCCNYTN TCNGARGGNGTNATHCCNGGNTTYTCNTCNGAYGARAAYATHAARTCNGARAARGTNTCN GARACNAARGGNGARTAYTCNGAYATHGAYTCNAGYGARATHCCNACNTTYYTNTCNGCN ------------------------YTNAAYAAYCCNGGNTCNAAYCCNGTNMGNAARGTN ATHTCNGTNTGYCARGARGAYCCNAAYTCNCCNTGGGARATGGAYTCNAAYCCNACNCCN GARYTNTCNMGNACNCCNAGYCCNGTNCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARCARYTNCARAARGCNATGGARGCNYTNACNAAYAGYGGN ACNGCNGTNGARGARYTNCARATGCARYTNAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TTYGTNGCNATHYTNTCNAARATGGARTAYGCNTCN AGYTCNGARGARACNGTNTGGAGYTTYTAYATHGTNCAYAGYCARAGYGTNYTNGAYCAR TGYAARGAYATGYTNCARTTYGCNGARAAYATHAARATHACNGGNCCNACNTCNTAYGTN CAYYTNYTNCARGARGCNGAYYTNYTNYTNAGYACNTAYATGGCNCARAAYAAYGTNAAR AGYTAYGARATGGAYGARTGYTTYACNMGNGTNAARMGNYTNYTNGGNGAYGTNTAYGCN CARCCNGGNGARGARAAYTGGMGNYTNTGYCAYTCNTAYTAYAAYAGYYTNGGNATHAGY ATHGAYTAYGTNGTNAARCARGCNYTNGARCARGCNAGYCARACNAAYCCNCCNGARTTY GGNAARGGNATHYTNGAYTTYYTNAAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARGCNAARYTN AAYGAYYTNATGGGNMGNCARAGYACNATGACNTCNAAYATHGAYTCNYTNTCNAARAAY GTNCARACNCARATHGCNAAYATHTCN------TCNTCNYTNCARGAYAAR---GGNGTN GAYAGYYTNTCNTCNTGYATHYTNCARTCNGCNACNGAYACNAARYTNAARCCNACNGGN ATHCAYGTNGARACNAAYTTYCAYCCNGAYGAYCARGARYTNAARAAYAAYTTYGTNYTN TTYGCNTTYTGYACNTTYATHGGNATGGARGAYGTNAAYYTNGAYGARCARAARACNGGN TCNAGYGTNCARTAYMGNTGYMGNTGYAARGCNAARAARGGNYTNAGYTAYAARTCNTGY ACNYTNTAYTAYTGGYTNTGYCCNMGNGGNAGYAARAGYAARAARACNYTNAARTTYGAY GGNTGYTTYCARTCNTGYTCNGARGAYGCNGTNATHCARYTNYTNCAYGGNAARYTNYTN ATGGARGARGGNATHTGGAARMGNTAYYTNGTNAGYGTNCARGCNTCNGCNYTNACNGTN TGGATGCARAAYGAYAAYCARGAYTGGAGYCCNGARYTNGAYTGGMGNYTNTCNGCNACN ACNCAYATHYTNCAYGCNTCNATHYTNCCNACNGCNGAYAARATHGCNATHGCNGCNAGY GGNTGGGAYAARACNCAYCCNATHGTNACNGTNTTYGTNTAYGAYTTYGTNMGNGAYGAY ACNYTNMGNTTYAAYATHCCNCAYATHGARCAYGTNTCNGAYYTNAGYYTNYTNYTNGGN ATHAGYAGYGAYACNCAYCAYACNCCNGTNCAYGTNGTNTTYCARTCNGAYTTYCARGGN GTNACNGAYTTYAARGTNGAYAARYTNCAYMGNGGNAARYTNAAYTCNYTNYTNYTNTGY CAYGGNCARGAYAARGCNTGYGTNAGYYTNACNTGGGAYCARMGNATHACNYTNTGGAAY ACNGARCAYMGNATGGCNATHCARACNGTNTCNATHCCNAGYCAYYTNCCNTGYYTNACN GARYTNGTNGAYGTNMGNGCNGTNAARGGNYTNYTNTTYYTNGTNACNTCNTGGMGNGTN GARGAYGTNGGNGAYTGYGGNGGNATHYTNGTNTGGAAYCCNGTNACNGGNTGYYTNGCN AARACNMGNGTNTGGAAYATHCCNAAYGCNGGNTGGMGNAGYACNGARAARACNAAYAAR GTNAARAARCAYATHTAYTCNACNAGYAGYTCNGGNTCNGTNTCNTGGTGGGAYGARMGN AGYGGNGCNATGGTNGGNTAYMGNCARTCNAAYATHGCNACNTGYGTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARGARGARATHYTNMGNMGNYTNCCNAARMGNYTNATHTAYYTNATGMGN TAYGGNGCNGTNAARGARGGNYTNAAYGTNGAYGARAAYGGNTAYGTNGAYATHACNGAR GTNATHACNACNCCNYTNYTNAGYGCNTAYTCNYTNCARGARATHYTNAAYGARGTNAAR ACNTCNATHTCNTAYMGNAAYACNCAYMGNTAYGARTGGMGNGARMGNGAYAAYMGNACN TTYATHMGNGCNGCNTAYYTNMGNAARTTYGARCARAGYCCNGTNCAYCCNGGNACNAAR GTNAARACNYTNGCNGARACNAGYATGGTNTGYGTNYTNGAYAAYYTNGAYATGTTYGAY YTNGARGARTTYCARGAYGARTAYGCNATHAARAAYATGATHMGNMGNYTNAARMGNAAR AARGCNATHACNAAYAARGCNYTNTCNGTNYTNTTYGTNCCNACNATHACNMGNATHGAY YTNGARGGNATHTAYYTNACNAAYAAYACNYTNMGNATGYTNTGGACNCARTGYCCNCAY YTNMGNGGNATHAGYYTNAARAAYTGYGGNTAYATHATHACNGAYACNATGYTNACNCAR YTNGCNAARAAYGTNCCNATGYTNGARCARYTNAAYYTNAGYMGNTGYTCNCAYYTNACN GAYAARTGYYTNGCNATHYTNTCNAARMGNYTNCCNCAYYTNAARATGYTNCAYATHGCN GGNGTNCCNGCNATHAARCCNAARTCNGTNTAYACNTTYYTNGGNGCNGCNCARGARYTN ACNTTYYTNGAYGTNTTYTAYATGAARACNACNATGGARGARTAYTCNTCNYTNATGAAR AARGCNGCNAGYYTNAARATHMGNYTNGTNYTNCAYTCNCCNAAR--------------- ------------------------------------------------------------ ---------------------------------GGNTGGACNGTNATHCARAARMGNCAR GAYGGNAGYGTNGAYTTYTAYMGNGGNTGGGARGAYTAYMGNMGNGGNTTYGGNAGYYTN GARGGNGARTTYTGGYTNGGNAAYGAYAAYATHCAYTAYYTNACNTCNCARGARCCNACN ATGYTNMGNATHGARATGGARGAYTGGAAYGGNAAYTTYCAYTAYGCNATHTAYGAYTAY TTYMGNGTNGAYAGYATGAARGAYYTNTAYMGNYTNCAYATHAGYGGNTAYCAYGGNAAY GCNGGNGAYTCNATGACNTCNYTNTAYGARAAYCAYGAYGGNATGCCNTTYAGYACNAAR GAYMGNGAYAAYGAYGGNMGNTAYTAYGAYTCNTGYGCNAARCAYTAYCARGGNGGNTGG TGGTTYAAYAAYTGYTTYGARGCNCAYYTNAAYGGNAARTAYGTNCCNTAYYTNGGNAGY AARATHAGYYTNATHTCNAARGCNGARATHMGNTAYGARGGNACNYTNTAYACNATHGAY CCNAAYGARGCNACNGTNGCNYTNGCNAARGTNMGNTCNTTYGGNACNGARGAYMGNCCN ACNGAYMGNCCNYTNCCNGCNMGNAAYGARGTNTTYGARTTYATHATHTTYMGNGGNCAY GAYATHAARGAYYTNCAYGTNTGYGARCCNCCNAARCAYCARCAYGARGGN---GGNGTN CCNCCNGAYCCNGCNATHGTNAARTCNTCNCARCCNCCNCCNGGNCCNGCNGGNGCNGCN TTYCAYGGNCARCCNGGNGCNGGNTCNGGNGGNGGNGGNCARCARTAYCARCCNTAYCCN CARCARTCNYTNTTYTAYAAYCARGGNGGNCAYCCNGCNCCNGGNTAYCCNCCNCCNCAY CAYGGNCARGGNGGNTCNCARGARGARGGNTCNCCNAAYGTNGARCARTCNCCNGAYCAR TTYTCNCAYGGNCCNGTNGGNGCNATHGGNACNMGNCCNATHTCNGGNTCNCARACNTCN ACNCCNCCNYTNAGYMGNAARTCNCCNACNTCNGAYCARGGNGTNCARGTNCARCCNMGN AGYCCNGARAARTCNAGYGGNCAYCARAARCCNCAYAGYCAYCAYTTYCCNAAYCARCAR AAYCAYAAYCAYCAYCARCAYCAYCARCARCARMGNGARTTYCCNMGNGGNGGNATGMGN GGNGGNAGYCAYCAYMGNATGGARGGNMGNAAYGARGGN---------MGNCCNAAYGAR GCNMGNGGNGGNATGTCNTCNTTYGTNMGNGGNMGN---------------GGNGGNAGY GGNGGNGGNAAYMGNGGNCARCAYMGNGGNCARGGNCAYCCNMGNCAYMGNGGNMGNGGN GGNMGNTCNTCNGARCCNYTNAARTTYGAYACNGAYTTYGAYTTYGARACNTCNAAYGCN CARTTYGAYAARGAYCAYATHGARAARGARYTNAARAAYYTNAGYYTNACNGAYAARCCN ATHAAYGGNGARAARACNGARGAYGAYCCNGARATHGARGARGARGARGGNGARGARGAR GAYGAYGARAAYGTNTAYTAYGAYMGNAARAARTCNTTYTTYGAYAAYATHAGYTGYGAR GCNACNGARAARAGYAARGGNCARMGNGTNACNTGGMGNGARGARMGNAARYTNAAYAGY GARACNTTYGGNATHTCNGARAAYTAYMGNMGNAAYTTYMGNGGNMGNGGNGGNTGGMGN GGNGGNAAYCARMGNGGNGGNTGGMGNGGNMGNGGNMGNGGNGGNGGNTAYCAYMGNGAR GGNGGNTAYTAY---GGNAAYMGNGGNGGNMGNGGNMGNMGNCCNGARTGGGAYTAYGGN GAYMGNMGNMGNATGGAYGCNCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNTCNCARCAYTGYACNCAYYTNGARTGGGTNGARYTNTTYACNATHTGGGCNGAY YTNGAYAAYGAYGTNTTYCAYCAYTTYACNAARAAYTGYCCNAARYTNAARMGNYTNTTY YTNACNTGGTCNACNCAYYTNACNTCNCAYGCNTTYGTNAAYTCNYTNGGNTGYTCNAAY ATHACNCAYYTNGGNYTNGCNGAYMGNCARGARMGNGARCCNTAYYTNAAYTTYGTNYTN CCNCAYTTYCCNCAYYTNYTNTCNYTNACNGTNAAYGGNMGNGAYGTNCAYTCNGAYGAY TGYGTNGCNYTNAGYAAYTGYTGYCCNATGYTNGARGARYTNGTNTTYGARYTNAARTCN ATGAARGAYCAYGAYTGYYTNTTYGAYTTYTAYYTNCAYCARCAYAAYACNYTNTCNGGN GAYAAYYTNGGNAARATHGTNGARGGNTGYCAYMGNYTNMGNAARYTNCAYGCNCCNTGY TCNCARGTNCAYGAYGARAGYATHYTNAARYTNTCNGTNAARTGYCCNTCNYTNGARGAY GTNAAYTTYATGCAYTGYCCNYTNYTNACNGTNCAYTCNYTNAARTCNYTNTCNGAYAAY TGYCCNYTNYTNAARTTYGTNAAYTTYCARCAYACNTTYAAYCCNCARGAYGAYYTNYTN GARTTYYTNCARAARTGYCCNYTNYTNCARGARATHAAYTTYGAYATHAGYAAYTCNGAY TCNATGAGYTTYTCNAAYTCNCCNYTNGARTCNCCNATHGGNGCNGCNATGTGYYTNATH GARATHAGYAARTAYTCNMGNAAYYTNGARGTNTTYTCNATHYTNTAYAAYMGNAAYYTN ACNCARYTNGGNATHTTYTCNATHTTYMGNTCNYTNGAYYTNTCNYTNMGNAARYTNMGN TCNTTYAGYTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYTAYCCNGCNGARGTNGARGTNTCN TAYGAYGARTTYAARTAYGTNGARCAYGTNYTNCCNAARGCNACNGTNCCNGARATHCCN CARCAYTCNTCNTAYCCNACNCCNTCNGGNTGGGTNCCNCCNAAYGAYGARGTNMGNTCN CARCARCCNTAYYTNGTNMGNMGNACNAARAAYCAYGTNYTNCCNGTNTAYCCNGARGCN MGNGARGTNTGGAARMGNATHAARCAYCAYGTNGTNATHMGNAAYATHGARGGNGAYATH TGGAARYTNGARTCNGARYTNMGNCARCAYYTNCARGAYCARACNAAYGCNGAYAARATH ATHACNCARGTNCAYGARGTNAGYMGNTGYATHMGNGTNMGNGGNGARCAYMGNGCNGTN ATHGCNCARTTYYTNYTNGAYAARGGNATGGARGARGTNGARYTNACNACNGAYATHGCN GGNGAYYTNGARYTNTCNTAYATHCARYTNCAYCCNMGNAARAARATGTGGAARGTNTTY AARYTNACNGGNGGNAAYACNTTYAARAARGAYCCNMGNACNYTNMGNTCNCARYTNATH MGNGARYTNCARGCNAARTGGAARGTNGGNATGATHTAYGGNAAYATGGGNTAYTAYAAY GGNGCNATHTGGYTNMGNATHCAYTTYGAYACNTCNMGNAARMGNAARAARAAYTCNMGN MGNACNGARGAYTAYAAYCCNAAYAAYTCNGTNTTYGTNYTNCAYTTYCARGGNTCNCCN TAYYTNATHATGAGYAAYGCNMGNGTNAARGARACNACNYTNYTNACNCARTCNYTNGTN GCNGTNTTYGAYGCNGARAAYYTNAGYTAYATGCARYTNTCNGAYMGNAAYGTNACNTCN YTNGCNGAYATHGCNYTNAARAARAAYATHGARACNTCNTCNYTNCAYMGNTTYAARGAR ATHGAYGAYAARGARAAYCCNYTNTCNTCNTAYCAYMGNAARMGNAARAARGARGAYGCN GTNYTNCARGAYGARGARGGNATHGTNGAYGARAAYMGNGCNGARAARMGNAARMGNMGN YTNYTNYTNGAYAARAARTTYGGNCCNTAYCCNCARCCNGCNYTNGARAARYTNGARTAY AARTTYAGYATHCCNTTYMGNGGNGGNCAYCARCARCAYCAYCARTGYAARACNGGNGTN GARATHAARGGNCCNTCNGTNYTNGARGGNYTNMGNCARYTNGCNACNAARGGNCAYYTN ACNTAYCCNYTNCCNMGNCAYYTNACNGGNGTNATHGCNGAYCARMGNAAYAGYTTYACN GTNGARYTNGAYTGYYTNATHCCNYTNCARCAYCAYGTNAAYAARYTNGTNYTNGTNGGN GAYCARGARCARYTNCCNGCNACNGTNYTNTCNCARGARGCNAARAARTGYMGNTTYGAY TCNTCNYTNTTYCARMGNYTNTAYGAYAARTTYGARTGYAARGARGAYGTNGARAAYCCN GTNATGYTNYTNAARCARCARTAYMGNATGCAYCCNGARATHYTNAARYTNCCNAAYTCN TAYTTYTAYAARAAYYTNYTNGTNACNGCNCCNTCNATHYTNAARTCNMGNGTNTCNAAY YTNAGYCCNTAYYTNGTNTTYGAYGTNYTNGAYGGNGTNGARACNACNGGNAAYAGYGGN TCNAARTCNAAYAARAARGARGCNAAYTGYGTNGCNYTNYTNTGYAARAAYATHGTNGAY ---YTNGTNYTNACNAARAARCAYACNGCNTCNCARTGYCARAARAARATHGGNGTNATH TGYCCNTAYACNGAYCARAARMGNGCNATHCARGAYAGYYTNMGNGCNYTNGGNATGTAY AAYATHYTNGTNAAYACNGTNGAYAGYTTYCARGGNCARGARAARGAYATHATHATHYTN TCNTGYGTNMGNGCNCARAGYCCNCAYCARTCNGTNGGNTTYGTNGAYGAYAGYAARMGN ATGAAYGTNGCNYTNACNMGNGCNAARYTNGCNCAYTAYGTNGTNGGNCAYMGNAARACN YTNAGYACNTCNGAYYTNTGGAARYTNYTNTAYGAYGAYGCNGGNCARMGNGGNYTNYTN GTNGARGTNCCNMGNACNGARATGTTYGCNGARATHGCNTCNAARMGNGTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AGYGGNAGYCCN AGYACNMGNGCNATHATHGAYTCNATHGGNGGNGAYTGYTCNAGYGCNGARMGNAARGAR AARYTNATGTCNGCNATHGGNAARAARGTNCARATGAARATGACNTCNAGYCCNTCNAAY CCNGTNAARAGYCARCCNAGYCARATHCCNMGNTTYATGGCNTTYYTNTCNAAYAARAAR AARGAYCARCARACNTCNGCNACNCCNGGNAGYAARACNTGGGAYAARATHCAYAARAAR GARTTYTCNAARTTYGAYTCNATHGAYGTNTAYYTNGARAARAARCARCARMGNAARGAR AAYYTNTCNGCNAGYACNAARAARMGNYTNTCNGCNAARAARTCNCCNGCNGTNAARCCN TCNTCNAARCCNTCNAARCARGCNTCNMGNGCNYTNGAYGTNACNAARATHTTYAARCCN ACNGTNATHACNACNAARAAYATHAAYTTYGAYTTYAGYAARACNCCNAARGCNAARGCN GTNAAYACNCCNTCNMGN---AARCARGCNCCNACNTCNACNAARYTNGGNTCNACNAAR AAR------------------------------------------------GTNTCNGCN ACNACNCCNTTYAARTTYACNGGNAAYTCNAGYACNACNTCNACNYTNAAYACNACNYTN TCNAARAAYAARCCN---GTNTTYGAYYTNAARGCNAGYYTNGCNAARCCNYTNAGYTGG AARCCNCAYACNGGNMGNYTNCARCCNGTNGAYACNAAY------ACNAARYTNTGYGCN GCNGCNCCNMGNTCNTCNCARAAYMGNGCNMGNAAYGTNYTNAGYMGNGAYTCN---GCN AAYAARATGMGNCCNGCNCARGCNAARAAYGTNMGNMGNGCNGCNCARYTNGAYMGNMGN AGYAAYCARAARTAYGTNGAYATGATGAARMGNMGNGGNYTNYTNGCNTTYGTNTAYGAY CAYGGNMGNCCNCAYTGGTCNCARGGNGGNCCNYTNTTYTAYCCNGCNCCNCARYTNGGN AAYTTYCCNAAYCCNCCNATGCARGGNCCNTCNCCNCARTGGYTNMGNGGNCCNTTYATH GGNGGNCCNGGNCCNCAYCARCARCARTTYGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGGAYTTY GGNTCNAARTTYGTNTAYYTNGGNAAYGARCARGARGAYGARGARGARGTNAARGTNGCN GARGTNGAYGAYGTNGTNYTNTCNGAYAGYGAYGTNAGYGAYGAYGAYGGNGARACNTGY GTNYTNGAYATHYTNGAYACNGCNGGNCARGARGARTAYTCNTCNYTNAARGAYCARTAY GTNMGNGAYGGNGAYGGNTTYGTNATHATHTAYAGYATHGTNGAYGARAGYAGYTTYAAR GARGCNGARGCNGTNTTYMGNTGGYTNAARMGNYTNMGNGAY---GAYAAYTGYCAYGTN ATHYTNGTNGCNAAYAARCARGAYYTNAARAGYGAYGCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GTNTTYAAYTTYMGNYTNCCNTTYTAYTAYGARYTN AARATHGTNTTYGTNATHTGGATGYTNTCNCCNYTNACNCARGGNTCNAGYTTYATHTTY AARAARTTYGTNCAYCCNCARYTNGCNMGNAARGARAARGARATHGAYGARATGATHGCN CARGCNAGYAARCARGGNTAYAGYACNYTNYTNTCNYTNGGNTCNAARGGNGTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG AAYTCNCARTCNTCNAARAARGTNMGNGAYYTNGCNMGNAARATHMGNATHAAYGCNACN CARGTNGAYYTNAAYGGNTTYGAYCCNTCNATHTCNMGNCAYTCNCAYCCNGGNGARGAY AARCCNCCNAARMGNCCNTCNACNGCNAARGAYGTNYTNGGNMGNMGNGCNACNTTYGGN GARATHATGAGYCARCARAARCCNACNYTNAGYGCNGGNGCNTGGMGNCARCAYYTNATH AARACNAGYGGNTCNCCNATGTCNGCNACNGCNCARCARMGNGTNGTNYTNGARGCNAAR AARAAYYTNAAYCAYACNMGNMGNGCNGAYGTNGCNGAYAARGTNAARGAYTTYATGCCN ATGCCNGAYATHTCNAAYYTNGCNATHCCNTCNGCNCCNMGNATHCCNACNCCNTCNTCN ATGCCNAARAGYTCNTCNATGCAYGGNGGNTAYGTNAAYGCNACNGTNTAYAGYCAYAGY MGNTCNCAYAGYYTNACNATHGARAARGGNYTNGAYGAYYTNAARCCNACNTTYATGAAY AGYYTNAAYTCNTCNAAYTTYAGYYTNACNGAYYTNGAYGAYGCNATHGAYYTNAAYAAR ---AARCAYATHTCNGCNGCNGAYGTNGAYAARATGCARCARGARATHCARACNYTNMGN AARTCNYTNYTNAGYGCNAARMGNGAYMGNTGGGTNAARYTNCCNGTNCARGAYACNYTN MGNMGNATHATGMGNGGNGARCCNTTYTCNYTNGARATGTAYMGNTCNYTNGCNGAYAAR MGNGARYTNGTNGAYTCNGCNATHAARACNCAYGAYGGNAAYGCNATHACNGCNGCNGTN YTNTTYATGAARAARACNACNAGYTCNCARATHTTYACNMGNGARATHAARCARMGNCCN GTNGCNGCNAAYCAYTAYYTNCAYTAYYTNAARGARCAYTAYGAYTTYAAYGARTAYATH GARACNYTNGGNATHYTNGGNMGNACNGARGARGCNGCNATHTTYAARTTYCARYTNGCN YTNCCNACNCCNGAYGTNGCNYTNAARATHTCNAARATHAAYGARTCNYTNMGNAGYCAY TTYAAYGCNGAYTCNACNYTNTCNTCNCAYTCNTCNYTNGTNCARGARTAYGTNGAYYTN YTNGARMGNCARMGNCCNATHGARGAYTCNGAYGCNAARTGYGARGCNAGYGGNCARAGY CARYTNTTYAARGAYTTYCCNMGNAARCARTCNYTNGTNGAYATGCCNGTNGTNACNACN YTNTAYTAYTGYTCNYTNTAYCAYTTYCAYYTNTCNGARAAYTCNYTNGGNAGYCCNGTN GCNATHMGNAARMGNCAYAAYATHTCNGARAARCARTTYGTNTGGACNAGYATHGGNGCN MGNGCNAARYTNMGNCARTGGAARGAYATHGARACNATHYTNACNACNAARGGNTGGTTY GGNGGNACNAARYTNAARGCNGTNATHGGNTTYGAYAARATHGTNGGNATHATHCAYAAR TAYAAYGCNCCNCCNGAYATHYTNGAYAARTAYYTNGCNYTNATGGAYGAYCCNGARGCN MGNYTNAAYYTNGCNAARAARGTNAAYTGYCAYAARTCNGTNATHGAYACNTAYGCNTCN YTNAARGAYMGNCCNTCNYTNGARAAYTAYGCNTCNCARYTNGAYMGNTAYTCNAARGAY GGNYTNTAYGCNTTYGAYGTNYTNAAYGGNTCNGTNGTNAARTGGMGNYTNGCNGCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATHCAYACNAGYAARMGNAAYCAYGTNAAYCAY MGNAARGARAARGCNGTNGTNAARCAYYTNTAYTAYAARAAYCAYGARAARTCNYTNGGN CAYTCNMGNAGYCCNYTNGTNGARYTNCCNGAYTAYACNTAYCARGAYGGNMGNCCNACN GARGCNACNATHAGYTCNAARGARMGNCARGARAARAAYTAYAAYYTNGCNMGNCARGTN GTNGGNYTNGTNGARGARATGAARTTYGCNCARAAYCARYTNGTNACNCARGARGARGCN AARGTNATHGCNGARGARAARMGNMGNAARTCNCARYTNAARCARAAR------------ ------------------------------------------------------------ ---------------------GGNGAYCAYGCNGGNATHYTNGAYYTNACNAAYCCNAAR TCNYTNCARTGGTAYYTNAAYAARACNAARAGYYTNCARCARGAYTTYAAYGTNACNTCN TTYAARTTYGAYGCNGGNGARATHAAYYTNYTNCCNGAYTCNTAYMGNTTYGARAAYCCN ATHGGNAGYCCNAAYCAYTTYACNAARYTNTAYGCNCARYTNGCNTAYGARGCNCAYAAR MGNCARGARGTNMGNACNGGNTTYAARAGYCARCAYYTNCCNATHYTNGTNMGNATGATH GAYMGNGAYAGYAGYTGGGGNGGNAAYGCNTAYGCNAAYGGNTCNYTNGAYGARACNGCN AARCCNGAYCCNGARYTNTAYATHMGNTGGYTNCARGCNACNGCNYTNATGCCNAGYYTN CARTTYTCNATHCCNCCNTGGTCNTAYAAYAGYACNGTNGTNGARATHTCNMGNAARTTY ACNAAYYTNCAYGARTCNTTYGCNTAYAARATHATHGCNYTNGCNGARAAYGCNGTNAAR MGNGGNGARCCNATHATGMGNCCNYTNTGGTGGATHGAYCCNGCNGAYCCNGAYGCNYTN GCNGTNGARTCNGARTTYYTNYTNGGNGAYGAYGTNYTNGTNGCNCCNGTNYTNGAYAAR GGNGCNACNACNMGNGAYATHTAYYTNTAYTTYATHYTNACNATGGCNATHTTYGAYYTN ATHGCNTGYGTNATHGGNATGCCNACNGARYTNTAYGAYYTNAAYAAYCCNTAYACNTTY TAYAGYCCNATHGGNTGYAARATHTTYMGNGGNTGYGARACNTTYACNATHTAYGGNTCN GCNATGGTNYTNGTNGARATHGCNTTYGAYMGNTAYTTYAARATHTGYMGNCCNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGTCNYTNGARYTNGTNTCNAARTGYYTNGARYTNGAR------GAYYTNATHGTNAAR GGNGARAGYTCNGGNAARAARAGYAARAARTTYAARTCNAAYAAYGCNATGGAYATGATH CCNACNACNMGNCAYGGNATHTGGAARGARYTNMGNAARGTNMGNCARAARCARCARMGN GARATHAARAARAARAARAARGCNGARATHTTYAARTCNGCNATGGARGTNTAYAARGAR ACNCAYGAYATHGAYCAYACNGAYMGNAAYGTNGARGCNYTNYTNAARATGTCNAARYTN GGNAARGTNGAYACNAARCAYGCNGARAARATHYTNTAYCAYCARCCNTGYMGNYTNTCN MGNGAYATHAARCCNGGNACNGARGTNTCNGARTCNACNACNGTNTTYACNGARGARGAY TTYGARGCNTTYGCNMGNGAYTAYCARCCNAAR---------ATGTCN------ATHCCN CAYGCN------------CCN---CCNYTNGGNGGNGGNAAYCARCARGAYMGNCARAAY MGNAARYTNYTNYTNGARCAYATHCARGARCARAARAARMGNYTNCARCAYGGNCAYCAY TCNTCNTCNTCNAGYAGYCCNACNCCNTCNATHAGYTCNGGNCCNACNTCNATGATGGGN AAYGCNCCNTCN---GTNCCNGGNYTNTCNGCNGCNGARTAYGCNACNATHAGYAAYCCN CARCARMGNGCNGCNYTNCARCAYGCNCAYGCNAAYTCNGTNGGNTTYTTYATHACNCAR GAYTCNTCNTTYGGNAAYYTNATHYTNCCNGTNYTNCCNMGNGTNCCNGAYYTNAARGCN GARACNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR AGYTGYCARGARGGNCARTGYTCNTTYAGYGAYCCNMGNATHTTYTCNTCNYTNMGNTAY YTNATHAARGTNCCNGARCAYACNTGGGGNGCNCAYGARTTYYTNGAYGAYATHGAYTGG GCNAAYACNAARYTNYTNACNGCNMGNAAYAARAARTCNTTYAARGARACNGARYTNACN TGGCAYGARCARMGNCARTTYYTNTAYYTNGCNATHAARGCNYTNAAYGAYCAYCCNGTN GCNGAYAAYGTNGCNAARGCNATHGCNCARYTNCARACNGCNMGNCCNGAYYTNACNGGN TAYGTNCCNACNCAYACNAGYCARGAYTTYAARTGYGCNGAYGGNGCNGTNYTNMGNTTY GCNACNGAYGGNTCNYTNCAYMGNYTNTAYGAYCCNGTNAAYAAYATHGARTGGGCNTCN CCNAAYCAYCCNYTNGGNCARYTNACNTAYAAYACNTAYATHGARGCNGAYTTYACNAAY ATGGCNAARCARTAYAAYTAYGARGCNGGNGTNGGNTTYGAYAARCCNAAYATGACNGAR AAYGCNCAYCCNGARGARAARCARTGGGAYYTNGGNGCNATHAGYTTYCAYMGNAARATH GAYGGNTCNTGYGAYTTYYTNATGGARYTNGARACNYTNGAYATHCARACNAGYATHAAR TAYGGNGCNCCNACNAGYTTYTTYYTNCAYTAYTCNGTNCCNTAYAAR---GGNYTNGAY GTNACNGTNYTNYTNYTNAAYAARACNACNACNMGNYTNCCNGARTCNYTNTCNYTNAAY TTYAAYCCNCARAAYGTNCCNMGNAARTGGYTNATGACNAARATGGGNCARGAYYTNGAY CCNTGYAAYGTNGTNYTNAAYGGNAGYCARTAYGTNCAYGCNGTNGAYACNTCNGTNAAR YTNACNGAYGARTAYAAYAGYGGNYTNGTNATHTCNGCNYTNGAYTCNCCNGTNATHYTN TGGGGNACNAGYCARCAYTCNCARTCNCCNTTYCCNGTNCCNYTNCARCCNTTYAAYTGY TCNACNYTNAAYTCNGTNGCNTTYAAYYTNTTYAAYAAYATHTGGAAYACNAAYTAYATH TAYTGGTAYCCNTAYAGYCCNTCNGAYAGYAGYTTYAARTCNMGNTTYAGYATHTAYTTY YTNTCNTCNAARGAYTAYTTYMGNGARACNYTNMGNMGNATGGARGGNGGNMGNGGNAGY TCNGGNTCNGAYATHATGGCNCARCAYGCNCARTAYGAYGAYGAYGCNGAYGTNGARTCN CAYTGYAARGARYTNCAYGGNACNTTYCARGAYGGNATGGCNTCNYTNATHCARCAYYTN ACNAARMGNTTYAARACNAAYACNYTNAARYTNAARGCNMGNGTNAAYAARATHGAYTGG TCNGGNTTYTCNYTNAARAARAARAGYGARCCNCARGGNCAYAARGTNAARGTNTCNTGY ACNGAYGGNMGNGTNTTYAARTCNCAYCAYATHATHATGACNGTNCCNYTNGGNGTNYTN AARTCNCARGCNCAYTCNYTNTTYAAYCCNAARATHCCNGTNGARAARYTNMGNGCNATH GARAARYTNGGNTTYGGNACNGTNTGYAARGCNTTYYTNGCNTAYGAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------MGNGARGGNMGNMGNTCNTTYGTNGGNGGNGGNCAYAAYTCN TCNCCNTCNGCNTCNATGTCNTCNTCNTTYCAYACNACNACNACNACNCCNCARCCNAGY CCNGTNMGNATGMGNGARMGNAAYTCNCCNMGNAARCCNMGNCCNGCNAGYGTNGGNACN TCNATGCCNAGYTTYGTNGGNGCNGARCCNGCNAARGCNTCNMGNAGYAARAGYTCNGAY MGNATGGCNMGNGAYMGNTCNAARACNMGNCCNGGNMGNMGN---------AARGAYAAR CCNGTNAARGAYTCNCCNGCNCCNGCNACNAARTCNAARGAYAARAARGARGCNGARGAY GARAARGAYGGNGGNAGYGGNACNACNAARAARGGNMGNGCNTCNYTNTCNTTYTTYGAY MGNYTNGCNACNCCNAARTTYCAYMGN---AAYCARGAYGARCARAARGAYTCNCCNGCN GCNAARAARGARTCNCCNATHGTNMGNYTNTCNCCNMGNAARGCNTAYTCNACNACNAAY YTNTCNAGYATHAARAARAARACNTCNTTYCAYGAR---AARACNAARGCNGTNACNAGY AGYAGYTCNTCNACNTCNACNACNACNACNACNCCNMGNMGNGAYCAYTCNGCNTCNACN CCNMGNACNACNMGNAAYGCNTCNCCNGTNCCNACN---GGNGGNATHATGTCNAARTCN GCNTCNGCNGCNGTNTCNTCNCCNMGNATHACNCCNCCNCCNACNACNTCNTCNTCNTCN TCNCCNCAYCCNACNCCNACNCCNAGYATHAGYGTNACNACNCAYGGNAAYGCNACNCCN ACNGCNAGYTCNGARGAYGGNACNGCNACNCCNMGNGCNTCNAGYACNAAYCARGAYATH TCNAARGARGARTAYAARGCNAARATGGCNGARMGNMGNMGNCARGCNMGNGARAARGCN GARMGNGARGCNGARGARGARMGNAARMGNCARGARGARGARMGNYTNGCNGARGARGAR MGNATHMGNGARGARGARGARGARCARMGNMGNYTNGARGARGARACNATHMGNYTNGCN GARGARGCNMGNAARGCNGARGARGARMGNYTNCARMGNGCNATHGARGCNGARGARAAR MGNAARAARGARGARGCNGARMGNYTNGARCARGARMGNAARGCNAARGARGARGCNGAY AARAARGCNAARGARGARGCNGARMGNATHGARMGNGARAARCARGARMGNGCNMGNAAR GARGARGARGARMGNCARCARMGNAARAARAARYTNGARATGATHATGAARMGNGTNAAR ACNGAR------------------CCNGCNCARGAY------------------AARGTN GARAGYCCNGTNAARTCNTCNGGNAGYTCNCCNAAYMGNAGYGCNYTNGCN--------- ---TCNCCNGARGTNCARGARATGCCNCCNTTYACNCARGARAGYGGNAAYTCNTCNGGN TCNGARGAY---------------------------------------GGNAARCARACN GAYGCNCCNGCNTCNAGYGTNTCNGAYGARAGYGCNGARAAYTCNGTNATHTCNACNTCN ------------------------------------------TCNTCNGAYTCNGCNCCN ACNATHGTNACNCCNGTNGTNMGNAGYGCNTCNTCNGGNGAYATHATHGAYAGYGCN--- GCNGAYGARGARAARAARGARATGGARAARGGNGAY---AGYYTNGGNTCNYTNAAYAGY AGYACNCCNATHAARTCNTCNTCNTCNACNAAYGGNACNACNGARTCNTCNACNGARGTN AARTCNMGNTTYAARTCNCCNYTNYTNCARCARYTNGTNGARAAYAARGGNGGNGGNGAY TCNCCNAGYGGNTCNCCNAARTTYAARTCNCCNYTNYTNCARAAYYTNYTNGGNAARACN AARGTNGGNGCNMGNATGGGNYTNTCNGCNAGYATGGGNGAYYTNAAYYTNAAYAARGAY AAYAAYAGYTCNAGYACNGCNACNAARGARGARATHAGYACNCARAAYCARCARCARGAY GGNGARAGYCCNGCNGGNTCNAGYAARGARATHTCNAARGCNGGNCARGAYGARGAYAAR GAYGTNGAYGARTCNGTNGGNTCNTCNGCNTCNTCNACNACNTCNGGNGAYCAYCAYAAY YTNCARGARGARTCNTTYAAYAARCCNCARCAYCARGGNAARTCNTCNTCNTGYGCNTCN GAYACNAAYAARTCNTCNCCNGARTTYTCNCCNATGGGNATGGTNGAYTCNGCNYTNGGN TCNAGYATHGARCCNCARYTNACNTCNCCNTCNCCNACNCCNACNACNACNTCNGTNATG TCNAAYGGNCAYGGN------GCNGCNCARAAYYTNATGGARGAYTCNAGYATHAGYATH CARACNCCNGARGARGTNTCNTCNGCNCCNACNGCNACNACNTTYGAYGAYGAYGARGAY GAYGAYGARAARGARMGNMGNGAYGGNGGNAGYGGNMGNTTYGARGARYTNATHGAY--- YTNCCNTAYTCNACNCCNAGYAAYTCNAGYAARACNGCNGTNTCNCCNATHATHGCNTTY GARGARAAYAGYATGMGNACNGCNGAYGTNGGNGARTCNATGTCNGARGTNATHACNATG ATHGARYTNCCNAAYGGNGCNAAYYTNGAYGTNTCNAARGAYYTNTGYYTNCARGTNGCN GGNATGTGGACNGAYAARCCNGTNGTNAARYTNGAYAAYATGYTNTAYGCNGGNMGNATH TCNGARACNATHGGNTCNCAYYTNTTYGTNGARTGYGARGGNGAYGAYTCNGARCARACN CAYAARAARAARGAYMGNGARATHTAYACNGCNCARACNAGYATGACNYTNGTNCCNATH TAYYTNGARGAYAARATHAGYTCNAAYGGNCARGTNYTNGARTCNCARTCNCCNTGGMGN YTNTCNTTYATHACNGAYGCNATHTGGGGNTTYATHAAYTTYATHGTNYTNTTYTTYCAR ACNATGTTYGAYCCNAAYAARAAYAGYMGNGGNGAYAAYTAYACNACNGAYTAYMGNMGN CCNGGNGGNGGNGGNCCNCCNACNMGNMGNATGGGNGGNTTYMGNGGNGGNMGNGGNGGN ------------------------------ATHATGTGYTCNAARTGYGAYAGYAGYAAR TAYCCNYTNTGYCARGTNCARCCNCCNGCNCCNGTNACNTGYGTNTCNTCNGGNAGYAGY ATHCCNCARTCNTGYAGYGTNGTNTGGGTNTAYAARAARGAYACNGCNYTNGAYCARTTY ATHMGNAGYTGYTCNATHTAYCARCAYGAYGARTGYTTYGAYAGYCARCCNGGNTAYGAR ACNTGYGCNCAYGTNTGYAAYACNGAYGGNTGYAAYTCNGCNCCNGAYATGTTYGGNGAY GGNYTNGGNAARAARAGYYTNATGCCNGARATHAGYCARGCNTTYACNGCNGTNAARAAY MGNYTNGAYTCNTCNYTNTCNAAYGAYGARGAYTCNCARMGNTAYYTNTTYGARGARGCN MGNGTNAGYGCNTCNACNATHYTNYTNCARYTNAGYMGNATHATHTAYTAYTTYGAYAAY ATHTGYAAYCAYATHCCNAARTCNYTNGARTAYCARYTNYTNTCNAGYTAYGCNGAYYTN ACNGTNGAYATHCARGTNGTNCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGTCNAGYGARGARGAYGAYTAY ATGTCNGAYAGYTTYYTNYTNAARTGYGCNGAYACNMGNCCNGGNYTNGCNTCNAARCAY MGNCARAARGARTAYGAYMGNGARAARAARCARATHGARTCNAAYAARMGNAAYACNMGN GTNCCNATHAARCARYTNGARATHCARCARMGNGARACNGGNYTNAAYACNACNATHTCN CARAAYAGYAARGGNTTYGCNYTNYTNCARAARATGGGNTAYAARCCNGGNACNGGNATH GGNAARTCNGGNGARGGNMGNGTNGAYCCNGTNGGNTTYGARGTNAARACNGAYMGNTCN GGNYTNGGNAARGAYTCNGAYATGAARMGNAARTCNTCNGARATGAAYAGYATGMGNGCN GCNATGYTNGCNAARMGNAARAARATHCAYGARAARCARGCNCARTCNTTYCARGAYMGN ATGMGNGAYAARTTYAGYGAYAARYTNYTNGARAARGAYYTNMGNGAYGCNCARAARGCN TGYYTNCARYTNGAYCARCARGCNGGNYTNGAYGAYCCNCAYGARCCNTTYTAYTGGCCN GCNAAYAGYYTNATHAAYAARAGYAAYGARGAYTGYCCNGAYGTNTCNAAYAGYMGNCAR CAYCCNACNAGYCARTTYGARCARTCNGAYGAYGAYGAYYTNGARGAYGGNGGNGAYGAR TGYGTNYTNGAYTTYAGYGTNGCNGARMGNACNGARATHATHACNMGNTAYYTNMGNAAY GTNTAYMGNTAYTGYATHTGGTGYGGNACNAGYTTYGARGAYGARAARGARATGGCNACN GTNTGYCCNGGNAAYTCNTCNGAYYTNCAYGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MGNCARATHTCNTGGCARAARGTNGGNACNGAYCAYTTYYTNAGYATHGGNACN GAYATHTGGGTNCARGAYCCNAAYYTNMGNATHAARCAYTAYACNTGGCCNGCNGARGTN AGYAAYTGGAAYYTNGARTTYMGNAARGCNMGNATGGARGAYAGYGGNGTNTAYGARTGY CARYTNATHTCNACNGARAARYTNACNTGGTCNGTNGARYTNTCNGTNATH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TGYCCNAGYTGYAARMGNGTNCAYGGNGARAARGTNGGNAAYTGYCCNGCNGGNTGG ATGACNTGGAAYTAYMGNAARGGNYTNAARYTNCCNGGNCAYAARGGNTGYGGNACNYTN GARGTNTCNTAYCAYATHCCNMGNGGNATHCARGCNAARGGNCAYCCNAAYCCNGGNAAR TCNTTYAAYGCNMGNGGNTTYCCNMGNACNGGNTAYATHCCNGAYAARGGNMGNACNGTN YTNAARYTNYTNATGGTNGCNTTYMGNMGNMGNYTNATGTTYACNGTNGGNACNTCNTCN ACNACNGGNGARAAYGAYACNGTNACNTGGAAYGAYATHCAYCAYAARACNGARGCNAAY TCNAAYTCNGGNCAYGGNTAYCCNGAYCCNAAYTAYYTNGAYAAYGTNYTNATGGARYTN GCNGCNCARGGNGTNACNCARGAYTGYYTNGARGARGAYGAYMGN------------GAY GAYACNATGGARAARTAYGGNATGGARACNTGYMGNTGYYTNYTNTCNGCNGCNGAYGTN TTYGCNTCNTCNAARYTNGCNAARAARGARCARGTNGARAARGCNGTNGGNAARYTNMGN AGYYTNAARMGNATHTTYAARYTNACNGAYMGNGAYGAYACNGGNTTYGTNGARAARTCN GARYTNMGNYTNYTNTTYAARATHYTNGARTAYCARGTNAGYGARGARYTNYTNCAYMGN GTNATGACNMGNTAYGGNGGNMGNMGNCARMGNYTNGGNYTNCARGAYTTYGTNCARGAR ACNGTNCCNATHACNGGNCCNATHYTNYTNACNGTNGGNGCNYTNTTYYTNATHYTNGCN TCNMGNCARTTYTTYYTNGCNCAYACNMGNAARAARGARGGNAGYGAYGGNTTYCARGCN CARGAYMGNGAYGTNCAYGARTCNTTYACNTCNYTNMGNCCNAGYGCNAGYGARYTNAGY ATHGAYACNGAYTTYACNGCNCARTGYTAYMGNATHGCNTTYTAYGGNAARGARCAYTTY AAYTAYTAYGCNAAYGAYGARATHYTNGGNCCNATHGTNATHTCNATHAARTCNGARACN GARCCNACNGAYGGNGTNAAYGTNATHGTNMGNACNAARTTYCARACNAGYGARGARGAR YTNTTYGGNAAYMGNTCNCAYAGYCCNGCNATGGAYACNTTYYTNGAYATGATHGGNCAR MGNGTNCARYTNMGNGAYTTYAARGGNTTYMGNGGNGGNYTNGAYACNGTNCAYAGYCAR ACNGGNGARGARAGYGTNTAYACNACNTAYAAYGGNAARGARGTNATGTTYCAYGTNTCN ACNATGYTNCCNTTYACNGARGGNGAYCCNCARCARGTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNAARGCNAAR MGNAAYGCNGTNAARGAYATHATHGAYAARTGYACNCARATGYTNMGNGARACNGCNAAY TCNCARACNGAYGARATHAARTCNMGNYTNGAYAGYATHAAYACNCARGCNGAYGTNGTN TGYCARYTNAGYGCNGARMGN------------ATGGAYCAYCAYTAYGGNGTNGCNGTN ACNAAYAARTTYGCNYTNTTYACNGAYGAYGAYGARGAYCCNATHGARGCNGTNYTNAAR GARGARMGNAARGCNAARGCNAARAARGCNYTNGARGARGAYAARAARGTNGAYAARCCN GCNGCNCCNCARAGYGAYGAYACNGARCARAARGARGTNGGNGAYAARCAR--------- ------------------------------------TGGCARACNGARAARGGNAARGGN AGYGCNMGNAAYMGNGARCCNMGNGARYTNMGNGARAAYGAYGGNGAYMGNMGNCCNCCN MGNMGNCARGGN------------------------------------------------ ------CCNMGNGAYTTYAARGAYGGNMGNGCNGGNGAYGARAAYGTNCCNCCNGARTTY MGNGARCARCCNCARGGN---GGNTTYAARMGNMGNGARGAYMGN------GARGGNAGY GGNTTYAGYGGNGARMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNMGN---GGNMGNGGN GGNGAYMGNGAYMGNCCNAGYGGN---GGNGGNGGNTTYGGNCCNMGN------GGNGAY CARAARMGNGARTTYGAYMGNCAYAGYGGNACNGAYMGNACNGGNATHAARGCNATHGAR AARAARGARGGNCAYGGNGCNCAYAAYTGGGGNAGYTTYMGNGAYGARATHGARGARCAR GGNCARGTNGTN---------GCNTCNGARGAR---AGYAAYGARMGNGARCCNCARCCN GARAARTCNGARYTNAAYGAYAGYGTNGARGGNGGNAAYGTNGCNGARGARGAYGCNCAR CCNCCNCARATGACNYTNGAYGARTGGAARGCNYTNCAR---GTNCARAAYAARCCNAAR CCNAARTTYAARATHMGNCARGCNGGNGARGGNGTNGAYTCNGCNCARTGGAARCARGGN GTNGARTAYCAYAARAARGTNGAYGARGARCARGAYCAYGGNGAR------------CCN GARAGYGAYCAYAGYGAYCARCAYGGNMGNGAYAAYAARCARYTNYTNTCNGAYATHMGN ATHACNTTYAAYGAYAAYCCNMGNMGNGGNMGNGGNMGN---MGNGGNGGNMGNGGNGGN ATGGARMGNGGNGGN---------MGNGGN------GGNMGNGGNGGNMGN------GGN GCNACNMGNGGNTTYGGNGGNAAR---AARGARGCNGCNCCNMGNTTY---GAYGARGCN GAYTTYCCNTCNYTNYTNAARACNGCNGCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYTAYTCNMGNCAYGGN GGNATGAAY---GGNMGNGCNGGNAGYCCNAARGTNAAYAAYCARGAYAAYTCNCAYGGN GAYAARTCNTCNTCNYTNTGGTCNAGYTCNGGNCAYAARYTNGGNCCNACNTCNCARMGN YTNCAYCCNCCNACNTTYCARAAYCCNTCNGARAARGCNTTYAARAAYTCNMGNTCNAAR MGNCARAAYCCNTCNCCNTTYGAYTAYGAYATGAAYGAYTTYATGGCNTGYAARCARTTY TTYATHATHGGNYTNAGYGGNGTNACNAAYAGYGGNAARTCNACNATHGGNTCNMGNYTN ACNAARGCNYTNCCNAAYTGYACNTGGATHTGYCARGAYCAYTAYTTYYTNGCNGCNGAY GAYCCNMGNGTNGARATHGAYGCNAAYGGNATGCARAAYTGGGAYACNYTNAGYGCNYTN GAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CAYGTNMGNCAYAARGGNAGYAARCARMGNATHAARAAYGCNAARGTNCAR GTNGAYAARAGYAGYAARTTY---ACNAARAARTCNAARAARAARTCNCARTCN---YTN AAYAGYACNYTNGTNGARAARAGYTCNATHATHGCNGARAARCCNGTNGAYAAYGTNTGG GTNMGNAARTTYTAYCCNACNCCNCARTTYTCNATHGARACNGCNGTNGARMGNCAYCAR GCNTTYGCNCARCCNGCNATGYTNGAYAAYATGGAYGGNYTNGTNTAYYTNGAYYTNYTN YTNGAYTTYTCNACNAARAARAARACNAARTTYATGAARAAYGTNMGNTCNACNYTNATH YTNCCNCAYCCNTTYAAYTGGGGNCCNCCNCCNTCNATHYTNGTNTTYTGYAARGARGAR GARCAYACNAAYYTNGCNYTNTCNYTNGGNGCNAARCAYGCNGGNGCNCCNGCNGARGTN ATHAARATGATHGARAAYGGNGTNYTNAAYCCNAARGAYTTYAAYCAYGTNYTNGCNACN GCNGAYTGYACNATGGARATHGCNCCNGCNMGNTCNTAYTTYMGNGAYAARTTYCCNCAR MGNGCNAARGGNAAYYTNGGNACNGAYYTNAAYGCNATGTGGTCNYTNTTYTAYACNGGN TAYTCNTAYGARTCNCARAGYYTNACNGARTCNCARGGNAARYTNCARGTNCCNATHGGN CARYTNAARCARCCNGTNGAYCAYATHGTNGCNAAYTTYGARAGYTTYATHGAYTCNATH TGYAARCAYMGNAGYGTNGCNYTNGGNCCNTTYATHAARTGGATGAGYGTNGTNGCNCCN CCNTCNCCNGARGTNTTYGTNGTNAARGCNGARGAYTAYGTNCCNGGNTAYMGNCARGAY GARGTNGAYTCNGAYGAYGARGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARACNCAYGCNATHTCNGAYTCNGARGGNTCNGAYGGNTCNGAYGAYYTNTTYGGNGAY GAYAGYGAYGAYTCNACNAGYGTNAGYTCNAARYTNAARGTNAARAARGAYTCNAARGGN GCNTAYGAYGCNGAYACNGAYGTNGARGARACNGARGAYTGYAGYACNGGNGARMGNAAR TCNYTNTGYAARTAYGGNAGYAARTGYTAYMGNAARAAYGCNTCNCAYYTNCARGARTTY TTYCAYCCNMGNCAYAARGARCAYAAYGAYATGAARGGNACNAAYMGNTCNCCNAARAAR YTNAARAGYGARCCNGGNCCNGARTCNYTNTCNGAYGTNTTYGAYGCNTGYCARCCNTAY GGNTTYTTYYTNACNMGNGTNTCNGGNGTNCARTCNCARTTYAAYGAYTGYGGNGTNATG AGYYTNAARGAYATHYTNTCNCCNGARATGGGNYTNYTNAARTGYTCNTGYCAYTTYAAY TTYATGTTYGARGTNCCNTGGYTNATGCARCARTAYGCNCAYACNGAYMGNTCNYTNCCN YTNYTNYTNGTNCAYGGNGAYCARGGNMGNGCNGARYTNGAYYTNAARGCNGARGCNTCN TCNTAYCCNAAYATHTCNYTNTGYMGNGCNMGNYTNGAYATHCCNTAYGGNACNCAYCAY ACNAARATGATGTTYYTNYTNTAYAAYTCNGGNYTNMGNGTNGTNGTNCAYACNGCNAAY YTNATHCCNAAYGAYTGGCAYCARAARACNCARGGNATHTGGATHAGYCCNATHTTYCCN CCNYTNAARTCNMGN---AGYGAYCCNGGNGAYTCNMGNACNAARTTYAARGCNCAYYTN YTNCAYTAYGTNMGNGCNTAYAAYTCNAGYAARYTNACNGCNTGGGARAARATHATHTCN GARCAYAAYATGGCNTCNGCNAAYGTNCAYATHGTNGCNTCNGTNCCNGGNMGNCAYGCN YTNCARGARAARCAYCAYTGGGGNCAYYTNAARYTNAARAARATHYTNTCNGARGTNGGN CCNGAYCCNGGNCARGTNAARAAYTGGCCNGTNATHGGNCARTTYTCNAGYATHGGNTCN YTNGGNGCNAAYCCNGAYGCNTGGYTNYTNAGYGARTGGGGNYTNTCNGTNGGNACNTGY GCNAARTCNYTNCCNTCNTCNYTNCCNTCNTCNAARYTNCARYTNATHTTYCCNTCNAAR GAYAAYATHMGNYTNAGYYTNGARGGNTAYAAYGGNGGNGGNTGYGTNCCNTAYTCNATH AARACNGCNTCNAARCARCCNTGGYTNACNCCNTTYTTYTGYCARTGGAARTCNGARGGN MGNGGNMGNTCNMGNGCNGTNCCNCAYATHAARACNTAYACNMGNTCNTCNCCNGAYGGN TCNCARGCNGCNTGGTTYATGGTNACNAGYGCNAAYYTNTCNAARGCNGCNTGGGGNGCN ATGGARAARAARGGNAGYCARYTNATGATHMGNTCNTAYGARATGGGNGTNYTNTTYYTN CCNGGNGAYTTYGGNTGYAARAAYTCNTTYAARGTNAGYAGYCAYYTNGGNAARYTNACN GAYCCNGAYGTNAARCCNTTYCCNYTNCCNTAYGAYYTNCCNCCNTCNACNTAYATHAAR GGN---AARAARTCNGTNGARYTNTTYTAYGAYGTNGTNTCNCCNTAYTCNTGGTTYGGN TTYGARGTNATGGTNMGNTAYCARCAYMGNTGGAAYATHAAYYTNAARYTNMGNCCNTTY TTYYTNGGNGGNATHATGCARTCNTCNGGNAAYAARCCNCCNGGNYTNGTNCCNAAYAAR GGNATGTAYGGNATGGTNGAYGTNGARMGNTGYGCNMGNTAYTTYGAYGTNCCNYTNATH ATHCCNAARAAYCCNGCNGARYTNATGTTYGARAARGGNTCNYTNAARGCNCARMGNTTY YTNACNGTNYTNGAYATGAARTAYCCNGARAARGTNGARGCNGTNTCNMGNGARTTYTGG ATGMGNGGNTGGAGYMGNGAYGARGAYYTNTCNGAYGAYGGNAGYATHGCNGARGCNGCN CARAARGCNGGNYTNAGYCARAARGAYATHCARGARTGYYTNTCNMGNYTNAARGAYCAR GAYGTNAARGAYMGNYTNAARAARGCNACNGAYGARGCNYTNGAYYTNGGNGCNTTYGGN TCNCCNATGATHGTNGCNGAYGTNGAYGGNAARAARCARTGGGTNTTYGGNAGYGAYMGN TTYCCNATHYTNGCNCARATHYTNGGN--------------------------------- ------------------------------------------------------------ ---------------------------------------------------------ATH GGNGCNGGNGTNYTNGGNAARAGYGCNATHGGNATHTTYYTNAAYYTNATHGTNGTNAGY MGNGGNGAYMGNCARMGNTAYYTNCCNTAYATHATHTGYGCNTTYTGYTAYGCNGGNGGN TTYTTYACNTTYGTNGCNGAYATGGTNATGGCNGCNAAYTTYMGNGCNCCNAARGAYATH CCNACNGGNGCNGAYYTNTCNGAYGCNGCNAARAAYYTNATHGGNGARAGYTTYTCNYTN GGNTGGGGNTTYGGNYTNGAYYTNYTNTCNGTNTTYGTNGCNTGYATHGCNGGNGCNYTN CAYYTNYTNGCNYTNMGN------------------------------------------ ---MGNGCNATHGTNGTNTCNGTNGCNGTNYTNGGNGTNGTNTAYMGNGGNACNATHCAR GCNGTNATHGAYAAYYTNTGGGCNTCNYTNMGNAARGAYACNYTNTTYCARTCNGCNCAY TAYGARACNATHTAYGTNACNATHGTNTAYACNGTNYTNATGATHTCNTAYCCNTAYGCN YTNCAYCAYATHCCNTTYTTYMGNMGNTTYAARGTNTCNCCNGARGTNAARTAYGTNAAY CARACNTTYGTNGGNATGGGNATHGAYYTNYTNTTYCAYYTNAGYCCNYTNYTNATHGCN GAYATGYTNATHATHAARMGNTAYCCNGGNGTNCCNTAYTCNGARATHGCNTCNMGNAAR MGNAAYTGGGTNGTNAARAGYMGNCCNYTNCCNCARGARTCNCCNGARTTYATHTCNATG TGYYTNCARGTNGCNGGNAGYGTNTTYYTNTTYGAYATHTTYTTYACNATHGTNCAYTAY GCNATGCAYMGNAAYYTNTTYYTNTAYAARTAYTTYCAYGCNCARCAYCAYGAYCAYGAR GTNGTNCAYGCNCAYGTNACNAAYCARYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GCNTGYATHGAY YTNACNGTNGAYATHGGNGGNGAYGARGTNATHGAYYTNACNCAYAAYAGYAAYATHATG GAYTCNCCNGTNGTNGTNATHAGYCCNGCNGAYGAYGTNGGNCCNATGMGNMGNMGNMGN GGNAGYGGNMGNAGYGGNMGNMGNMGNTCNGGNTCNMGNGGNYTNGCNTCNMGNTAYTCN TCNTCNTCNGAYGAYCARTCNGCNGCNTCNTCNTCNTCNTCNMGNGTNCAYCARATHGCN GTNGAYAGYGAY---------GAYGARYTNCCNGAYATHCCNTTYGCNGTNCCNAAYGAR AGYTCNAARGCNAAYGCNAGYTTYTGYAARTCNCCNCCNYTNCARATHCARTGYCCNGTN TGYYTNGAYGAYYTNAARCARATHAARTCNAAYAAYMGNMGNGTNATGTCNACNATGTGY GGNCAYATHTTYTGYGARGARTGYATHATHAAYGCNATHMGNACNTAYAARTCNTGYCCN ACNTGYMGNAARCAYYTNGCNCARAAYAARATHCAYCCNYTNTTYYTN------------ ---------GTNTCNGAYCCNGAYTCNGAYGTNACNATGTCNCCNMGNGARGGNTAYAAR YTNAARMGNCARAAYMGNAGYAARACNYTNCCNGGNAGYACNGARGARGARAAY------ TCNACNAARGTNCARMGNGCNAGYTCNCAYMGNGCNAGYTCN---------------TCN CCNGARGARCCNGCNTCN---------------TCNGGNAGYGTNAARAARYTNGGNTCN ACNMGNTTYAGYCARTTYGARTCNTCNAAYGCNTCNGARCCNTCNTGGATHAAYAARGCN AARCARAARAARGAYCARTCNGARAGYGARGARATHGAYGCNAARAARCARTCNGARTCN TCNGTNMGNMGNMGNAGYTAYGAYAAYGCNTCNTCNTCNAARTCNTCNCARCCNGTNACN TCNCARACNACNAARCAYGTNCCNTCNTTYTCNACNACNCCNAAYTCNAARYTNACNACN GAYGTNAAYACNACNAGYAAYAGYMGNACNGCNGARTCNGAYAARGAYAARAAYGARGCN TCNAAYAAYAARMGNTCNAGYATHGAYATHTCNAGYACNAARMGNGARAGYATHGAYATH GAYGTNMGNGARYTNTCNATHAARCARMGNACNGCNTCNTTYAAYACNGTNGGNAARGCN GARAAYGTNMGNCCNTAYAARTGYCARTGYGGNACNACNTTYGCNMGNAAYGARGARYTN ACNMGNCAYCARMGNATHCAYTCNGGNTAYAARCCNCAYAARTGYCCNGTNTGYAAYAAR ACNTTYGGNMGNAARGAYCAYYTNAAYAARCAYGTNAARACNCAYYTNCAYTCNTCNCAR AARAARGTNTAYYTNTGYGAYGTNCCNAAYTGYGARCARACNTAYACNMGNTCNGAYGCN YTNGCNMGNCAYCARACNAAYTCNCAYGGNATHAARACNAARCCNTCNAARTGGMGNCCN CARATHAARTTYAARYTNGARATH------------------------------------ ------------------------------------------------TGGTAYAARTCN GAYATGATHAARTGYGTNGCNAARGTNYTNGGNGTNTGGGTNMGNAARGARGTNGAYCCN AAYACNAARAARATHAGYTTYAARATHAARGGNMGNCCNGARGAYGTNCAYAARATGAAR ACNCAYYTNTCNGAYAARGTNATHGAYATGATHGGNYTNGCNCCNAARMGNGGNACNAAR GAYTTYATGAARTAYGCNGCNACNTGYATHGAYAGYGTNCCNTCNTAYTGGACNAGYAAR ACNMGNGGNCAYGGNCAR------------YTNGTNAGYGTNGAYGARCARACNACNATH GCNATHTCNGAYYTNGTNGARAARTGYTGGGARCARCARYTNGTNGGNCARGGNAAYGAY GCNGCNGGNATHCCNACNAAY---TCNATHAARGTNATGAARGTNGARMGNYTNGARAAY CAYTCNYTNTTYYTNAARTAYTCNNNNAARMGNAARGCNGTNTTYMGNGAYATGTCNGAY MGNGGNAGYYTNTGYAARGGNATHGGNAARYTNAAYGGN---AGYAARGGNCCNACNACN ACNATGCARCAYYTNCCNMGNTTYATGAARAARGARYTNTTY---TTYGARATHAAYGAR YTNTAYYTNTTYCAYGGNACNAARTCNGAYATHGTNTCNGCNATHMGNGARCARGGNATH GAYAAYMGNYTNTCNAGYGCNAGYGCNATGTTYGGNCARGGNGTNTAYATGGCNGARAGY TCNACNAARTCNGAYCARTAYGCNGAYCCNMGNGGNGTNMGNYTNCCNCCNAARACNAAY YTNACNATGYTNYTNACNMGNGCNACNYTNGGNGAYGTNTTYYTNTGYGAYCAYAAYCAY GARAGYGTNGCNTCNAARAAYACNCARAARYTNMGNMGNCCNCCNTGYACNAGYTGYTTY AARGAYYTNTGYMGNTGYGCNAARCCNYTNTTYCAYTCNGTNATGGGNGAYGGNAARTGG YTNTTYMGNGARTTY------------------------MGNGTNYTNAAYGAYGTNMGN ATGGAYGTNGGNGCNYTNAARGAYGAYTCNMGNCCNGTNTTYCARMGNCCNCCNAAYTCN ATHGGNYTNTAYYTNGAYGCNYTNGAYGCNMGNCCNGAYMGNAAYACNACNGTNGGNTCN CAYCAYGCNTTYATGATGAGYGTNATGGAYMGNYTNCARGARCAYYTNMGNGAYYTNGAY YTNTGYAARYTNAARGGNGGNATGGARACNMGNMGNGTNGGNAAYGGNGTNATHTTYGAR GGNGTNAARCAYAGYTGYATHATHTCNYTNACNTTYGAYAGYYTNGCNGAYYTNGARGAY TTYCAYACNYTNCAYAARAARAAYMGNYTNACNGCNGTNTTYCARGAYATHYTNGTNGAY MGNGCNYTNYTNAARYTNACNAAYTGYGTNAARYTNACNYTNMGNGTNAARYTNTGGGAR GAYGARATHAARGCNTGYAARGARGAYYTNMGNAARMGNTCNGAYGCNMGNGTNAARYTN TCNAGYTCNGAYMGNGAYCARGGNYTNGTNAARMGNATHCARGARTAYGCNAARYTNYTN TCNGAYAARGTNGCNMGNGCNMGNGAYATGGARAAYGARTTYGARMGNAARYTNGGNGAR TTYATGYTNACNATHAARCARATHYTNCCNCARAAYACNCARGTNATHAARACNATHAAR GARTTYCAYACNAAYYTNAARATGGCNMGNGGNGTNAARMGNGTNAAYTAYAGYACNATH GAYAAYTAYYTNCARTCNYTNGARTTYTTYMGNAARTCNTTYCARGARATHGARMGNGAR ATHGTNTTYCCNATGYTNCARATHCARGGNGTNTGYGARAAYGARAARCARMGNAAYYTN AARAARACNATHAARAARGCNGCNTCNGARATGYTNAGYTAYYTNAARCCNGAYGTNGAY YTNCARAARGTNMGNCAYAARGARTGGGARGGNAARGTNYTNACNMGNGARCAYGGNYTN TTYTAYGGNYTNATHAGYYTNATHCCNATGAGYTTYGAYMGNYTNACNACNATHGAYTAY AGYYTNGAYGARTAYATHAAYGAYTTYCCNGARATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNCCNTGYTCNGTNAAYGAYTAYGGNGAYCAYAARGTNGTNTGGYTNGAY CARTAYTCNMGNYTNYTNACNTAYATGGAYMGNMGNATHGTNGAYGAYAAYMGNYTNAAY GTNGARMGNCCNTAYCCNMGNGARTGGAAYYTNCAYYTNMGNGAYGTNTGGTAYGCNGAY MGNGGNATGTAYCARTGYCARATHAAYACNAARCCNATHMGNGTNAARAARGTNTAYYTN AAYGTNGAYCCNACNGCNGCNACNACNACNAGYMGNGAYGGNGGNGTNACNTTYYTNAAY YTNMGNATHAAYAAYGTNGARCARTCNGAYTAYGGNGTNTAYACNTGYGCNCCNTTYGGN GARGAYCARAARGAYGTNACNCCNACNGTNCARACNATHGAYACNTCNATGMGNYTNTTY ACNTGYCCNATHMGNGAYATGCARTCNTGGAGYGARGCNGGNYTNTAYGAYGGNYTNATH YTNTTYGARATHTAYGGNYTNGTNYTNTCNGGNCCNACNGAYTCNYTNGTNTGYGGNGGN AARGARTTYTAYATGMGNGAYCARTCNGCNACNATHMGNTGYGTNTTYTAYCARATHGAY MGNGARYTNCCNCARYTNATGAARGGNCARGTNTAYMGNYTNGTNGGNTCNATGGAYAAY AARAARCARGGNTTYAARGTNYTNTCNATHMGNAARGCNGCNACNGAYGARMGNATGGCN TGYCARGAYGCNACNGARGTNTCNYTNCAYGARATGGAYMGNYTNGCNMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNAARCARTTYCCNMGNGTNGCNGAYATHCCNGAYYTNATGAARYTN TTYMGNACNTCNTGGYTNGARAARYTNAARGAYGTNMGNAARGCNGARMGNMGNGAYGAR GARTAYATGAARGARYTNTTYMGNCARGTNTTYATGGAYGCNGTNTTYCCNATHCAYCAY GTNGCNACNATGCCNGCNTAYMGNATGGGNGAYGARGAYAAYGAYAARYTNMGNCARGAR AGYYTNYTNMGNTAYAAYGARACNAARMGNGGNAAYAARACNGCNYTNGCNGCNYTNYTN TCNCCNGAYYTNGTNTTYGARCCNATGYTNGTNGAYGARGTNGCNTAYAGYGTNATHGGN CCNAAYTGYYTNAAYAARCCN---------YTNGTNGTNCARGCNGARGARYTNGGNTGY GARGGNAARGTNGARGARTCNCARGGNGTNATGAARYTNGTNGAYCARYTNAARGAYGAR MGNCAYCARYTNGARATGAARCCN---GTNATGCARGAYGAYGGNGGNCCNYTNATGAAR CARATGGARGTNTGYGAYGTNTGYGGNGCNTTYYTNATHGTNGGNGAYGCNCCNCARMGN CARGAYGARCAYYTNATGGGNAARCARCAYGCNGGNTAYGCNCARGTNMGNGCNGARATH GAYMGNMGNAARAARAARGTNMGNGAYGARACNGARGCNMGNGARGCNAAYGARACNMGN YTNMGNYTNGARMGNGARGARMGNGARAARGARMGNCARMGNGARMGNGARGARMGNMGN ---MGNGARMGNGAYMGNGAYMGNGAYMGNGARMGNGAYMGNGAYMGNMGNMGNMGNAGY MGNTCNMGNAGYMGNGAYMGNGGNGGNGAYMGNMGNMGNTCNMGNAGYMGNGARAARMGN MGNCARMGNAGYTCNAGYMGNGAYMGNMGNAAYMGNMGNAGYMGNAGYMGNAAYAARGAR ------------------AGYTCNGGNMGNAGYAARAARTCNMGNMGNTCNTCNAGYMGN GARMGNAARMGNGARMGNMGNCAYTCNMGNGAYAARAARTCN------------MGNAGY MGNTCNMGNGAYMGNAARGTNMGNAGYGGNGAYGAYYTNGARMGNAAYGGNGGNGGNACN AGYAGYAARGARAAR------------------------------------AGYATHACN GAYGAYACNYTNGTNACNGARTGYCCNAARAARYTNATHGAYYTNATHTCNGCNCAYYTN AAYGGNAARTGYGGNAARAAYTGGGARGAYYTNYTNGAYYTNTAYGARTAYACNTAYAAR GARATHAARYTNTTYGCNAAYAARGAYCAYCCNGARGGNTAYTTYTGYACNATGYTNAAR GAYATHGAYTTYCARGAYTAYAGYATHGGNTTYYTNAARGARGAYYTNGAYMGNATHCCN AARMGNGAYACNYTNATGGAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TTYGCNATHGAYYTNGGNATHGCNTGYGTNGTNTGYMGNCARTTYGAY GTNAGYTCNGGNAAYCARYTNGTNGARTGYCARGAYTGYCAYAGYYTNTAYCAYCARGAR TGYCAYAARCCNACNGTNACNGGNCARGAYGTNAGYGAYCCNMGNTTYGTNTGGTAYTGY TCNMGNTGYACNAARAGYTTYAARAARATGATGGCNCARAARCCNGTNAAR---CCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CCNTCNYTNACNAGYAARCCNYTNACNCAYGTNACNAAR AGYMGNCCNMGNCCNCCNMGNTCNGTNMGNCCNACNMGNCCNGTNYTNGAYACNGGNACN ACNGARATGGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNAAYAAR ACNTCNYTNGTNTTYCARGCNGCNGTNACNGCNGCNAGYAAYGGNTGYAARGTNGTNCAY ATHTGYACNCAYCCNYTNTCNAARYTNCCNGCNCCNGTNCAYGGNATGTCNAGYCCNGAR CCNTCNGTNATGAARAAYGTNGAYTTYYTNTAYTTYGARGARACNACNGARATGGTNGCN TAYTTYGCNAGYATHCAYATGAARMGNAAYYTNCCNAGYTAYATHATHGTNGARGAYATH YTNTCNTAYGCNTCNCARMGNCARGAYMGNCCNGTNGARMGNAAYYTNGCNAARYTNYTN GCNYTNATHTCNAAYGCNAGYACNTGGACNGCNGAYCAYAAYGAYACNGGNMGNTGYAAY GTNYTNYTNACNGCNCCNTCNMGNATHAARTGYATGCARAAYGTNYTNAARCARTTYGAY TAYMGNGTNTCNACNTAYGARGGNCCNACNAARGAYAAYGTNTAYTCNACNYTNTCNTAY ACNGGNATHAARGGNCAYATHTCNYTNACNTTYCAYMGNCARAGYAAYTCNYTNATHYTN AAYGAYGTNGAYYTNACN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATH GTNCCNACNAARCARGCNACNGTNGAYATHTCNGGNCAYCCNACNGAYATHGTNGTNAAY AARTTYGARGAYMGNYTNTTYATHATHATHACNCARTAYCARAARYTNGGNACNGTNATH GARGTNTCNMGNGAYGTNATHAGYGAYGARGTNCARGGNCAYATHCCNATGTTYTCNACN AAYGTNYTNYTNGGNAARGAYGARCCNYTNTCNCAYGTNATHGCNAARACNATHGTNATH AARYTNAAYCCNCCNATHCCNGTNGTNYTNACNYTNGCNYTNAARGARACNTCNCAYACN ACNGTNCARGCNATHGTNGAYGTNATHAARTCNTGYYTNATGGCNACNAAYGARCAYTTY GARGCNMGNMGNMGNCARATGGTNYTNGAYAARGCNTCNMGNGCNMGNAARGARATGGCN YTNACNCARCARCARTCNGAYMGNGTNGTNGCNCCNTCNGCNCARGGNCCNAARCCNGAR ACNATHATGTGYACNGAYCARGGNCARTTYTAYCARACNMGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGCCNAAR TTYTAYGARGAYATHGARGAYCARCCNACNMGNCCNAARYTNGCNTGYGARGGNATHMGN GAYGAYYTNYTNGARTGYYTNYTNAARAGYGAYTGYTGYMGNAARGARAARAARACNCCN MGNGARTGYATGAAYMGNYTNGGN---------GAYCCNTCNGTNCCNGAYGARTGYCAY AARYTNMGNGTNGCNTTYTTYGAYTGYMGNMGNTCNATGYTNGAYATGMGNACNMGNTTY MGNGGNMGNAARGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GCNGCNAGYAARAARTCNGGNTCNTCNAGYGGNGGNYTNTCNACNGGNTCN CARGCNGCNATHGGNGTNYTNGTNATHGCNTGYATHGGNGGNGTNGCNATHGGNATGTTY GCNTGYTAYMGNMGNAGYAAYGTNACNAGYMGNAGYYTNATGGCNTTYYTNACNGGNGGN GTNMGNTAYAARACNTAYACNAAYGCN--------------------------------- GARGARAARTCNMGNAARAAYGCNATHCARGCNAARATHAAYMGNGARAARAARAARGCN TAYATHAARAAYYTNGARGAYGARATHACNTCNYTNAARGTNGAYAAYGCNAARYTNAAR TCNCARAAYGARMGNATGCARAGYAAYATGTCNGCNYTNGARGARGARGTNGARTAYYTN AARTCNGTNYTNGTNAAYTCNAGYTCNYTNTCNGGNYTNYTNAARAAYATHTCNAAYGTN AAYGARGTNAARYTNTCNGCNACNGTNYTNGGNMGNAARMGNTCNGTNGCN------GAY GAYCAYAGYTAYAAYTTYGTNGARTCNGTNCCNGARAARMGNGCNMGNMGNATHAAYGAR AAYYTNAARAARGCNGGNGTNTGYYTNCAYGTNAAYGGNGGNTCNGCNTGYYTNGARTTY TGYGCNCAYTGYTCNAARYTNGCNCARAARTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ACNACNTTYGGNGGNCAYATHGAYCAYAGYAAYCCNGGNGGNACNAGYTAYGGN GTNAAYGCNGGNCAYACNTGGAAYCAYGGNGGNGGNAGYAARACNACNGTNTCNGGNGGN TTYGAYCAYAAYTCNCAYTCNGGNAAYAAYTTYGGNATHGGNGTNACNCAYACN------ ---------------AAYAARGTNTTYGTNGCNGTNCAYTCNGGNGCNGGNAAYCAYTCN AARGCNAAYGARAGYTAYAGYAARAAYGTNTGYAARATHGCNTGYATHCARGCNATGGAR YTNYTNAARGGNAARMGNTCNGCNATGGAYGCNGTNACNGCNGCNGTNGTNGCNYTNGAR GARGAYGARAGYACNAAYGCNGGNTTYGGNTCNAAYYTNAAYGTNCARGGNGAYGCNGAR TGYGARGCNTGYATGATGGAYGGNTCNTCNYTNTAYTTYGGNGGNGTNGGNGCNYTNTCN GGNGTNMGNAAYCCNGTNAARGTNGCNAGYYTNYTNGTNGCNGARCARMGNYTNGGNCCN YTNCCNTTYGGNMGNGTNMGNCCNAGYATHYTNGTNGGNAARGGNGCNAARGCNTTYTGY GTNGAYCAYGGNATHGAYACNAAYTGYAAYATHGTNTCNAARTCNGCNTTYAARACNTAY AGYMGNTAYAARMGNAARTGY--------------------------------------- ---YTNTCNGAYCCNAAYAAYGARACNAARMGNMGNAARGTNGARTCN------------ ------------------GTNCCN------------------------MGNGGNATHACN YTNATGCARGAYACNGTNGGNGCNGTNTGYGTNGAYCAYGARGGNAAYGTNGCNGCNGCN TCNTCNAGYGGNGGNATHTGGYTNAARCAYCCNGGNMGNYTNGGNCCNATHTGYATGTAY GGNGCNGGNTGYTGGGCNCARAAYCARGCNTCNAGYAGYAARCCNGGNGTNGCNGTNGTN ACNTCNGGNTGYGGNGARCAYATHATGCARACNYTNYTNGCNAARACNTGYTCNGAYGGN ATHMGNTCNCCNGAYAAYYTNTCNCARTCNYTNTCNCARGTNTTYCARACNCAYTTYYTN GARTCNGARTTYYTNTCNGCNAARCCNGARAARTAYGGNGGNGTNYTNGCNYTNAARTAY GARGARACNTCNGCNGGNAARGARYTNGARYTNGGNTGGATHCAYTCNACNAAYAGYTTY TGYTTYGCNTTYATGGARGGNGAYCARMGNTCNCCNAARGCNGTNATGTCNTCNYTNGAR GAYTCNTCNAAYGCNGGNAARTCNTTYACNATGGGNGGNCAYYTNGTNATHYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CCNGTNATHMGNATHGTNYTNAGYGCNGCNACNGGNYTNYTNTTY GGNATHGCNYTNGARAARGGNMGNGTNTTYGARCCNCARATGATHMGNGAYCARATGYTN TTYAARMGNTTYGCNATGYTNAARATGTTYYTNTCNGCNTCNGCNATHGGNATHYTNTCN TTYTCNTTYYTNTTYGGNATGCCNCAYACNATGMGNAARATGGCNYTNGCNATHCARAAY TTYCCNGARMGNCCNCCNGCNAARTCNYTNYTNGGNATHGTNGTNGGNGCNGCNATHYTN GGNTGYGGNATGACNATHGCNGGNGCNTGYCCNGGNACNACNYTNGTNCARYTNGGNACN GGNGTNACNAAYGCNTGGATHACNATHGCNGGNGGNYTNYTNGGNTCNGTNGCNTAYGCN ATGACNCARGCNGAYYTNCCN------GCNATGTTYMGNGCNGCNAARCARCCNACNTCN YTNGAYAARATHYTNGAYGTNCCNTAYCCNGCNATHGCNGTNCCNYTNTCNTGYATHYTN GCNGGNGTNGTNTTYGGNYTNGARTGGTTYTCNCCNTGGTAYGARGARGTNGARTCNGTN ------ACNGARGGNGTNATGMGNGCNGGNGCNTGGCCNCCNTTYATHGCNGGNGCNATG ATHGGNATHYTNCARYTNCCNACNGTNYTNGGNAAYGARGAYACNYTNGGNTCNGCNAAY TCNTAYGTNACNYTNATGTCN---------ACNATHTGGCCN---------YTNAAYAAY GARGARAAYTAYTTYAARCARTAYMGNTAYGGNYTNAAYMGNTGGTGGCARGTNATHCAY GTNACNGCNGCNGTNTTYGGNGGNGCNYTNTCNGCNACNGCNTCNGGNTCNATGGGNACN GTNCCNGGNYTNCCNTGGCAYCAYGCNYTNTCNGGNGGNTTYYTNATGATHTAYGGNGCN MGNYTNGCNGGNGGNTGYACNAGYGGNCAYGGNYTNTCNGGNTTYGGNYTNYTNGCNYTN ATGTCNTTYGCNGCNGTNCCNGCNATGTTYGGNGGNGGNATHGCNACNGCNGTNTTYATG AARTAYGTNYTNCAYGTNGARATG------------------------------------ ------------------------------------AAYAARCARCARGARATHAGYTCN GTNATHAAYMGNTAYCARCARGARGTNGCNACNYTNCARCARYTNYTNAARGARGCNGCN GAYACNGCNTCNGAYAAYACNGCNGTNCARTAYGARTCNGARMGNAAYAARYTNGTNACN YTNAAYGARAAYTAYGARGARGARATHCARGAYYTNMGNAAYAARYTNACNCARGARMGN GARGGNTTYYTNTCNGCNGTNGCNAARTCNATHAARTGGGTNGGNACNGTNGGNAGYAGY TCNACN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGTCNGAYTAYMGNGGNMGNGGN---MGNGGN AGYAGYTGGMGNGGNGGNCCNCCNMGN---GGNGGNTTYMGNGGNGGNMGNGGNGGNTAY ATGATHGAYMGNGAYGGNGGNMGNGGNGGNGGNTTYMGNGGNMGNGGNGGNTTYTCNMGN GGNMGNGGNGGNCCNCCNMGNAGYMGNGAYGAYYTNTCNCCNCCNMGN------ATGTCN MGNAGYTAYGAYACNACNGAYMGNGGNMGNGGNCCNCCNCCNAGYMGNMGNAAYGAYMGN TAYGARGAYAGYTTYGAYMGNGGNGGNCCNTCNATGMGNATGAARGAYYTNTAYTCNTCN CCNCCNMGNGAYTCNGGNMGNAGYTTYGAYMGNCAYTCNCCNCCN------CCNMGNMGN GAYMGNGAYTAYCCNCCNMGNCAYAGYAGYGAYTAYACNAGYTCNAGYMGNGAYTAYYTN GCNCCNMGNAGYTAYAGYCCNCCNMGNGAYACNGGNTAY---AGYTCNTAYAARGAYTCN TAYAGYTCNGTNCCNMGNGARGARMGNMGNCCNATGMGNGAYTAYCCNCCNYTNMGNGGN GGNGGNGAYTAYGGNGAYCAYCAYGGNAGYAGYMGNGAYTTYMGNGAYGGNCCNMGN--- GGNGGNGGNAGYAGYTCNMGNGAYTAYCCNCCN------------------------CCN TCNTCNMGNAAYGGNGGNGAYTTY---------------MGNGAYTCNYTNAGYAGYMGN GAYTTYMGNGAY---------------GCNCCNMGNGGNGGNGGNGAYMGNTAYGAYAGY MGNGGNMGNGGN---GGNAGYAGYMGNGGNMGNTCNMGNTTYGAYGAYAGYMGNGGNCCN CCNCCNMGNGAYTAYAGYTCNMGNGGN---------------MGNGGNGAYMGNGAYGAY GAYMGNGGNAGYMGN------GGNTTYATGAAYGGNGGNTCN------MGN--------- ------------------------GGNTCNMGNGGNGCNGGNMGNGAYMGNAGYGGNMGN GARGGNGCNGGNGGNAARMGNCCNMGNATGGARTCNAGYGAYTAYMGNMGNTCNTCNTCN ATHYTNGARACNAGYATHGGNAARGAYGCNGAYTGYGARMGNGTNTTYAARMGNTTYACN TAYAARTGYYTNCARATHATHGTNCARTCNMGNATHGARAARGARACNTCNAAYGAY--- ---------------TAYTTYAGYATHAAYYTNCCNGAYAGYGGNTCNATHGAYGARCAR ATHAARTAYACNYTNGARGGNATHAARTCNTTYCCNGTNAARGAYMGNTCNATHTGYGTN GARATHGCNYTNMGNACNAGYGAYGGNGAYCAYATGTTYYTNGARACNTGGGAYATGAGY TTYAAYYTNAGYAGYYTNGAYATGTCNGCNAGYAARGTNCARCAYATHTTYACNMGNATG GGNYTNACNYTNAARTCNYTNYTNTCNGCNACNMGNGCNACNCCNGCNTAYAARYTNGCN AARAAYCARGGNGARAARGGNGGNGGNTAYAARYTNAAYTAYMGNTTYTAYYTNGGNCCN CCNAARACNCAYATGYTNGGNGARAAYTTYAARACNATGMGNGCNGGNGCNGTNCCNTCN GCNTTYGGNYTNYTNAGYATHGGNGTNTCNTAYMGNACNAARYTNYTNYTNTCNCCNGAY AGYGCNGCNTCNTCNTCNATHGTNATGCARGTNACNGAYGAYTAYTTYATGAARGARACN ACNAARCAYTCNACNGGNCARGTNTAYTCNGAYCCNAARCCNTGYYTNTCNTTYGTNAAR MGNMGNTCNTCNYTNTCN------------------AGYCCNGARAAYATGGCNGCNACN CCNTAYAAYTAYACNATHTCNCCNTCNTCNCARGGNACNGAYGARGAR---ATHATHTCN AARYTNTCNTCNGARAAYAAYCCNATHCCNTGGCCNYTNGCNAGYATHYTNAAYATGGAR GARYTNCCNGARCCNGCNGTNGGNGCNTTYTCNGTNCARMGNCCNAAYGCNCCNMGNGTN GARGARACNGAYYTNCCNTTYGARGGNYTNATGAARMGNAGYATGATGYTNGARMGNAAR CARAARCARGARYTNAGYGARMGNACNGAYGAYAGYGGNTTYGAR--------------- ---MGNTCNAAYGARTCNMGNCARCARGGNACNAAYGARGARGARAARGARAAYYTNGAY GTNYTNAAY---------AAYAAYYTNCCNYTNGARGARGARGAYTAYGTNATHGTNCCN CCNTTYGCNTGYGAYGARGAYCCNMGNGAYGTNAARTCNTTYYTNGGNGTNATGTTYMGN GCNCCNCAYYTNTAYGARYTNCCNGARAAYAAYYTNACNGTNAAYGAYTAYYTNCAYGAY GTNGGNCARATGGTNTCNMGNYTNGARCARGAYATGCCNATGYTNGAYGARTTYTGYCAR TCNGTNATHGARTCNACNAGYGCNGARGAYGARGAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CCNTCNCCNAAYGGNGCNGTNCCNCCNCCNGCNCAYGCNCARCCNMGN AARMGNAGYTAYCCNTTYGARTCNCARGGNAGYYTNTTYCCNAGYCCNGAYATHGTN--- ------------------------------------------------YTNGTNCCNYTN ACNTCNTCNATHMGNYTNATHAARGAYATHATHTCNYTNTTYGTNMGNMGNYTNGTNGTN YTNYTNGARGARGGNAAYATHYTNCARAAYGCNGARYTNTCNAARAARTGYYTNGARTGY YTNAARCARTTYTGGTCNYTNTGYTCNMGNCARCARAAYGTNATHTCNTCNTCNCARTGG TAYGGNAAYTGGCAYCCNGTNYTNYTNGARGARATHACNCCNYTNTCNTCNATGTTYATH GAYYTNTTYATHTCNGCNTAYGARCAYAARGARGAYCARGARYTN------TGGTCNMGN MGNYTNTAYAGYTGGYTNAAYTTYGAYYTNCCNGAYMGNGCNATHAARATHGCNYTNYTN GARGCNGARGCNCAYMGNMGNGTNGGNGCNAARYTNGCNGGNCCNGTNGTNAGYMGNATH YTNCARMGNAARTTYGAYGTNTCNTCNAAYCCNGAYTAYYTNYTNCAYTTYYTNYTNYTN AARAARTGGCARGGNYTN---GCNTCNYTNTCNAAYATHACNGARATGTCNAARTAYYTN AARGCNCCNGCNTCNTTYYTNTCNTGGYTNCARMGNTAYTGGAARGGNAGYAAYGAYTAY ATHCCNGARGAYACNAGYYTNGARGGNGCNGCNGTNAGYCARTGGYTNYTNAARYTNAAY ACNGARMGNGTNYTNGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TGYGGNGARGGNACNAARACNAGYAARMGNATHTGYGGNGGNCARAARTAYAAYGGN AARCCNTGYGARGGNGAYGAYACNAARGARGCNGCNTGYAAYMGNGAYMGNTGYCCNATH YTNCCNMGNAAYTTYCARATGTCNCARTGYACNGAYAARAAYTTYACNTGYGCNAGYAAY YTNATGTGYATHCARGGNAAYCARAARTGYGAYAGYACNGTNCARTGYCAYGAYGGNTCN ------------------------------------------------------------ ------------------GAYGTNGARGGNAGYGGNAARATHAGYGGNGCNAARGCNTCN GARYTNTTYTGYGCNTCNGGNYTNAAYCCNGAYGCNYTNMGNCARATHACNGARYTNTGY GGNGCNAARMGNYTNGGNCAYTTYGGNMGNAGYCARTTYTAYATHGCNYTNAARYTNGTN GCNATHGCNCARGCNGGNYTNCCNATHAARYTNGAYTCNYTNAAYTCNGGNGCNMGNTTY CCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARTTYACNGAYGAYGARATH MGNCARGARYTNGCNCARYTNGGNTAYCAYAAYGTNCCNCARGAYAARYTNGARGGNTTY AARAARGAYYTNATGGCNYTNATHTCNAARGARMGNAGYAARACNAAYTCNTTYAAYAGY AGYCAY------------ACNACNGARCCNGGNAGYAGYAARAARGARGTNTCNMGNCAY GCNGGNTAYTTYGTNGAYAAYAGYTAYACNGAYCCNGGNMGNCARTGGATHGGNGGNTCN MGNTTYAARGARGAYTGGCAYTAYGGNGGNGARAAY------------------------ ---------------------------------------------------------GGN YTNGGNCARYTNMGNCCNCARACNGCNCCNGGNGARMGNGGN---------YTNGTNATG GGNATGGAYGAYTAYMGNGAYMGNGARAAYCARAGYTGYYTNCAYGAYGAYGTNTCNGAR ACNAGYTCNGARACNMGNTTYATGAARMGNAARACNTCNMGNAARACNCCNACNGGNTGY MGNATGGTNGAYGARTCNTTYACNGAYACNGARTCNGGNGTNTTYGARATHTAYGARAAR ATHAARAAYYTNGCNATGMGNGARTGYGARTGYGGNAARACNMGNACNAARTCNGGNGAY GTNGARCCNCCNTAYMGNATHAARGGNAARCCNAAYAARTAYCCNTCNGTNATHMGNAAR YTNGARCCNCCNCAYACNMGNAAYYTNGTNAARACNGAYGTNAAYGARMGNCAYAARATG TAYAARGARGCNTGGAARAGYCARCCNCCNATHGGNGARGAYCAYMGNATHCCNYTNMGN AARGCNATGCAYTGYMGNYTNATGMGNCAYGARGAYGTNMGNACNAARCCNAARGTNTAY ATHCCNAAYCARTAYGTNCCNCCNCAYGARAARYTNMGNAARGAYGTNMGNTGGAARGTN MGNCARGCNTTYGARMGNTAYGARYTNCCNGGNCAYGGNTTYTAYCAYGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AGYTCNGARYTNGARACNGAR YTNGCNGTNGTNAARMGNCARGTNACNYTNTTYATGGAYGAYTTYAAYAARGARCAYCAR GARMGNYTNTCNGTNGAR---------AARACNYTNCARAARGARMGNGARTCN---CAY CARTAYYTNGARACNAARYTNMGNAARGCNCAYGCNYTNYTNAARTCNMGNGAYGARGAY YTNMGNCARAARTCNAARCARGTNGCNGAYYTNCARTAYAARGTNGAYGAYYTNAARYTN AARYTNGARGTNGARCARMGNMGN------CAYCCNCAYGCNATHTCNACNCAYGAYCAY TAYTAYAARGGNATGYTNYTNMGNTCNGGNAGYCAYATHMGNGGNGCNTCNMGNACNGCN ACNYTNYTNYTNATHGARATGGARTCNAARCAYMGNAARMGNMGNGGNTGYTGYYTNTGY ATHYTNCCNTTYYTNYTNYTNYTNCCNYTNGCNYTNYTNGCNAGYCAYTAYGTNAGYCCN CCNGGNYTNACNCCNGAYCARGTNAARGCNATHGTNCARGCNATGATHTCNGAYAARATG GGNTCNATGCARACNGARATGGAYTCNMGNATHGAYYTNGTNTCNGGNGTNTTYAARGAR GAYATHTCNGGNYTNAARTCNAAYYTNYTNGGNYTNCARACNCARATHCARGAYACNATH MGNGARACNCARGCNYTNGCNGGNGTNGAYGARACNAARGCNTCNATGAARAGYYTNAGY GGNGARCARAGYGCNGAYTTYYTNGCNGCNTCNCARCAYYTNGARTCNAARTTYYTNGAY YTNMGNAAYGAYGTNAAYGARYTNGAYAAYCARAAYACNGCNTTYYTNGCNATGYTNAAR TCNTGYTGYCARAAYAAYACNGCNYTNGCNTCNACNGTNMGNGCNCAYATGATGTCNATH YTNTCNGARGTNGGNAGYGAYGAYAARGAYTCNGCNYTNGCNGGNYTNATGGCNTGGATG CARGARAAYTAYGTNGCNMGNGCNGARYTNGAYAARAARYTNTCNYTNGTNGCNGCNGGN ATHACNGARAAYYTNCARTCNYTNYTNGCNGARMGNGTNGCNGGNGARATHAARGCNTCN ATHGTNTCNGCNAGYATHGAYGARATGGCNGTNAARTCNATHGTNGARGARGCNYTNGTN CARTTYAGYGCNGAYMGNGTNGGNATGCCNGAYTTYGCNYTNGARTCNGCNGGNGGNAGY GTNYTNAGYGTNMGNTGYTCNGARACNTAYTAYMGNAARACNGCNYTNGTNAGYGTNTTY GGNYTNCCNYTNTAYTAYACNTCNAAYTCNCCNMGNACNGTNATHCARCCNAAYGTNCAY CCNGGNGARTGYTGGGCNTTYAARGGNAGYTCNGGNTTYGTNGTNATHCARYTNTCNCAR GCNATHCARGCNACNGGNTTYACNYTNGARCAYATHCCNAARAGYYTNGCNCCNTCNGGN ACNATHGAYAGYGCNCCNMGNTCNTTYACNGTNYTNGGNYTNACNTCNGARAAYGAYYTN GARGGNATHCAYATGGGNAAYTTYACNTAYYTNGAYAAYGGNAARCCNATHCARCAYTTY CCNGTNCARAAYGGNCAYCCNGGNGTNTTYCARTAYATGGARYTNMGNGTNACNAGYAAY CAYGGNAAYCCNGARTAYACNTGYATHTAYMGNTTYMGNGTNCAYGGNYTN--------- ---GARTAYCARTGYCCNTCNMGNYTNGCNCARMGNYTNTCNCARATGGTNATHGTNGAY AARCARCAYATHCARTCNGAYTAYMGNYTNCCNYTNCCNACNTCNGTNATHTCNTCNYTN GTNGAYCCNCARMGNCARAAYGARACNTCNGARATHAARGAYCCNATHAGYCAR------ ------CAYACNACNGGNAARCAYGCNAARGARATHATGAARATHMGNCAYMGNAARATG AARAARCAYAARYTNAARAARYTNMGNAARMGNATGTAYTTYGTNTGGMGNAARCARAAR YTNACNMGNMGNGCNAARMGNGAYGCNATHTAYTGGAARGARGTNGCNGCNATHAARAAR GAYGGNGARGAYTTYGAYGCNGARACNTTYGTNAARGAYCARYTNGARAARGCNMGNMGN GGNGGNTTYTAYATHAAYGTNTTYGARTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AAYTCNYTNAGYYTNATHTCNYTNATHGCNGCNGTNYTNTTYGCNATGAAYTAYATG GTNGGNTTYTCNGTNGARAAYTCNATHYTNAARGARAARACNAARACNCARATHGTNACN GTNYTNAARTCNTCNGCNYTNYTNYTNATHGTNAGYTTYACNTAYCAYTTYATHGCNGTN YTNTTYGGNGCNCCNGTNTTYACNCAYGTNTCNGARACNTAYCAYTTYGCNATHYTNATG ACNGTNYTNACNGGNYTNCCNYTNTGYGGNATHGCNGGNCCNAARYTNGAYAARTGGATH GARATHTTYACNACNGAY---MGNGARCCNGGNYTNCARACNATGGTNTAYYTNAGYTCN ATHGGNGCNGTNYTNGGNGCNTGGYTNGGNGCNGTNCCNATHCCNYTNGAYTGGGAYMGN CCNTGGCARATHTGGCCNATHAGYTGYTCNATHGGNTGYGTNTCNGGNTAYTCNGGNGGN YTNTTYATHGCNTCNYTNTAYYTNCCNCAYCARTAYAARGCNYTNYTNAARCCNAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TTYCCNACNATH GAYGCNMGNYTNTGYGARYTNAAYATGAARCAYGCNTTYGTNATGCARGARMGNGARGGN MGNCARATGGCNGARATHYTNTGYAARTGGYTNCARTCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TAYGTNTGGCARATHAAYAAR MGNGARGCNCCNCCNYTNYTNYTNAARGCNCAYAAYGCNGARGTNACNTCNGTNGCNTGG TGYCCNATHGAYYTNACNAARGARAGYTTYGAYATHYTNTCNMGNTAYMGNTGGYTNCAY GAYTTYCARGTNATHGAYATHYTNAARAARGAYATHYTNMGNAAYATHCCNCCNTCNTGG MGNTCNTGYYTNGCNCARYTNGARGTNGARGAYYTNAAYGAYGTNCCNTTYYTNGGNGAR GGNAGYMGNGAYAARTAYCCNGARTGGCCNGARTGYYTNMGNGCNTTYYTNCARGAYTCN AGYMGNYTNGCNGGNTGYMGNAAYGAYGGNGTNAGYGCNGARGCNGTNGARATHGARATH AGYATGGCNMGNGGNATGAARAGYAARAARYTNCAYGARGTNAARMGNYTNGCNTCNYTN GTNCARGARGTNGTNGCNGARGCNAAYTGYAAYYTNGTNATHGAYGTNGGNTCNGGNYTN GGNTAYYTNGAYCAYGTNYTNCAYCARAARTAYGGNATHCARGTNYTNGGNATGGARACN GTNCARAGYCAYGCNTCNGCNGCNGARATGMGNGCNGTNAARCARGGNATHACNTGYAGY GGNATHAARAGYYTNCARTGYCAYYTNGARGARAARGARGARTCNTAYAARGCNTTYGTN AGYCARGTNGARTCNGTNTTYCCNACNYTNAAYTGYGAYTGYMGNYTNGCNGGNGGNACN GARACN------------------------------------------------------ ------------------------------------------------------------ ------------------------------ACNCCNTCNACNTTYGARAARTTYCCNYTN AGYGAYATGGGNCARMGNATHTAYYTNCAYTTYTCNAGYAARACNGGNGGNTCNTTYATH ACNCCNTCNACNYTNMGNYTNGGNGCNCARGARACNMGNAAYMGNTGGMGNGARCARACN AARAGYGAYCAYGARAAYCAYATHAAYCAYGTNGCNTTYMGNGGNYTNYTNACNYTNACN GAYGARGARGARGGNCAYATHMGNCARAARGTNMGNCAYTGYGCNTTYGGNTCNATHCAY GAYTTYGTNGAYTCNTAYTAYGGNCCNCARTCNGAYGAYGAYCCNACNYTNACNGARAAR MGNGAYYTNYTNTCNYTNCAYGAYCARCAYAARAARGAYTTYGAYGGNATHGARATHYTN ACNYTNYTNCARGTNATHYTNCARCCNGTNATHGARAAYYTNATHTAYCARGAYMGNGCN CARTGGYTNMGNGARCARGGNYTNATGAAYGTNAARGTNYTNCCNATHTTYAAYGARTCN ATHTCNCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARCCNYTNATHGCNYTNYTNTCNGCNGCNGTNTTYAAYTGGGAYAAR GARMGNGTNTCNGAYGAYGARGTNAARMGNTGYYTNCARGARYTNAAYGARGTNAAYCAR YTNGTNAARAARACNAARTTYTAYCARGARAAYCCNCARYTNGCN--------------- ---------------------------CCNCARAAYCCNGTNTGGGARYTNGTNGTNGAY AARGAYGAYTTYAARGTNTGGMGNMGNAARYTNCCNAAYTCNGAYYTNTTYAARTAYMGN GTNYTNGGNCAYTTYAARGAYATHCCNGCNMGNGCNTTYTAYAAYACNCARGTNGAYGTN CAYTAYTGGAARGAYTGGGAYGCNCARACNACNGAYGTNMGNATHGTNGAYMGNGAYGCN ACNACNGGNTCNGARGTNATHCARTGGGTNTAYAARTTYCCNTAYCCNATGTAYCCNMGN GARTAYGTNTAYGTNMGNMGNTGYTCNATHTAYCCNGARMGNAAYGCNATGATHATHACN GCNMGNGCNACNCARCAYCCNAARTGYCCNCCNAARGARAAYAAYGTNMGNGTNGCNACN TAYAARTCNCARATGGTNATHACNCCNTAYACNTTYTTYGAYGARGAYGGNTTYTCNTAY GTNATGACNTAYAGYGAYGAYCCNCARACNAAYTTYCCNCCNATGTGGTAYAAYTGGGTN GCNAGYTCNGGNGTNCAYGARTTYYTNCARMGNYTNCAYMGNGCNGCNYTNAARAARCAY GGNGARTCNACNGTNGAYTAYACNTCNAAYAAYGTNGARGGNCCNCCNTCNAAYYTNTAY TCNGGNATGGTNCAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AAYTCNYTNTCNGTNAGYGCNYTNATHTTYACN TTYAARYTNYTNYTNTGYCARAARTTYGARAAYGGNGGNYTNAGYTGYTCNGARGTNTTY GCNCCNATHTTYGTNYTNGCNCARGTNTTYATGTTYMGNGCNTGYMGNATGCAY------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGCNGAYATHGTN GARCCNCCNCCNTTYGARAAYGARGARGAYGARGTNAARGARGARGAYGAYYTNTTYTCN GAYGCNAARGARAARCCNTCNTCNCCNGAYACNGTNAGYCCNCAR------TCNGTNAAY GGNACNGAYGAYAAYATGTTYGGNAGYGAYGARAARGAYGARGAYGAYYTNTTYAARGGN GGNTCNTCNGARATHAARYTNGARTCNGAYGARGARGARGTNCCN------GAYGTNAAY AAYAGYGARGCNGCNMGNGCNGARGARCCNTCNGCNGCNGCNGCNGCNCCNGCNAARAAR GARGTN------------------------ACNCCNGARATHTCNGTNTCNGARGTNATH ACNGCNAARACNAARATHGCNGCNCCNTCNYTNAARTCNGAYGAR------YTNGARGAY ACNGAYGAYAARGARCARTAYGARATHGAYATHAARATHACNGARAAYYTNAARATHGGN GAYGGNATGTCNGCNTAYATGGTNTTYAARATHYTNACNAARACNACNAAYCCNGCNTAY MGNAAYCCNGARAAYGTNGTNYTNMGNMGNTTYAGYGAYTTYYTNGGNYTNTAYGCNAAR YTNGCNGARAARCAYGTNCCNYTNGGNATHGTNGTNCCNCCNGCNCCNGARAARAGYGTN ATHGGNATGACNAARGTNAARATGTCNAARGARGAYACNGGNTCNATHGAYTTYATHGAR MGNMGNAARGCNGCNYTNGARMGNTAYYTNATHMGNACNGCNGCNCAYCCNGTNYTNGTN TCNGAYCCNGAYTTYATHGARTTYYTNCARAARGAYGGNGAYYTNCCNAARTCNACNAGY ACNTCNGCNYTNAGYGGNGCNGGNGTNATGMGNYTNTTYCAYAARGTNGGNGARTCNATH GARAARATHACNYTNAARGTNGAYGARAGYGAYGARTGGTTYGARGARAARCAYCARCAR ATHGARGCNYTNGAYGTNCARYTNAARAARYTNCAYTCNAGYYTNGARACNYTNGCNGCN CAYMGNMGNGARYTNTCNAGYAGYACNGCNGTNTTYGCNAARAGYGCNGCNATGYTNGGN AAYGTNGARGARCAYACNGCNYTNTCNMGNGCNYTNTCNCARYTNGCNGARACNGARGAR AARATHGARATHGTNCAYAARGAYCARGCNGARGTNGAYTTYTAYACNATGTCNGARYTN ATGAARGAYTAYGTNGCNYTNATGGGNGCNGTNAARGGNGTNTTYCAYGARMGNATHAAR ACNTAYAARCARTGGAARGAYGCNGARACNATGYTNGGNAARAARMGNGARAAYAARGCN AARYTNGARATGCARGGNAARGCNGAYAARYTNTCNCARGCNMGNACNGARATHACNGAR TGGGARCAYMGNGTNGARAARGGNCARGARGAYTTYGARAARATHTCNAARACNATHMGN AARGARGTNGCNMGNTTYGARAARYTNMGNGTNTCNGAYTTYAARACNAAYGTNATHAAR TAYYTNGARGTNYTNATGGARAAYCARGARAARYTNATHAARTAYTGGGARACNTTYYTN CCNGARGCNAARGCNATHGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGNYTNMGNGAYYTNAGYAAYGAYCARGAYCCNGGNGAYGAYCCNAAY ACNAARGGNMGNMGNGTNTAYTTYTTYMGNAAYGGNGAYCCNAAYTAYAARCCNAARCAR GTNYTNATHAGYAGYMGNACNTAYCARAAYTTYGARAARYTNYTNGTNGAYYTNAGYACN ATHGTNGARACNTCNACNGGNGTNAARTAYATHTTYTCNTGGCCNGAYGGNAARGARATG AAYTCNATHACNCARTTYGARAAYGGNAARTAYTAYATHTGYTCNAGYACNAARAARYTN AARTGYCCNGTNGARGGNTGYGAYAARAGYTTYCCNTAYCCNACNGTNYTNMGNMGNCAY ATGAARGTNCAYMGNGGNTAYACNTGYGAYGTNGAYGGNTGYGGNAAYGAYTTYGARACN TAYTTYCARYTNMGNAARCAYAARGCNGAYGARCAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CCNAARGTNCCNATGGAYAAYGAYGAR ATGTCNGGNAAY---AGYGCNGARAAYGGNGAYGGNGAYMGNCARGTNYTNGCNCCNTCN GARGGNCCNMGNGARGARYTNATHAAYACNGCNATHAARTTYYTNCARAAYCCNAARGTN ATGGGNAGYCCNYTNAAYCARAARAARGCNTTYYTNAGYAARAARGGNYTNACNCARGAR GARGTNGAYYTNGCNGTNGARMGNGCNGGNGTNACNGAR------ACNGCNAGYAAYGCN ATGAGYCARGCNMGNCCNCCNCCNCCNGGNTAYCARCCNGGNATGATGGCNCCNTAYGGN CARGTNCAR---------------CCNCCNATHCCNCCNCARTCNGGNTGGGCNMGNGTN MGNGAYGTNACNYTNACNTCNGTNGTNGTNGCNGGNGTNTCNTAYGCNYTNTAYCAYTTY TAYAARACNTAYYTNGARCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CAYGGNGAYGAYGAYGCNATHAAYGARCCNACNATHACNGCNAAR ATHGCNMGNTGGTGGMGNCARAARMGNYTNCAYGGNATHTGYMGNGAYATHCCNAARTGY GAYCCNAARTCNATGATHCAYCAYATHTCNMGNYTNCCNGARTGYMGNAGYTTYYTNCAR AARGARMGNACNMGNYTN---YTNMGNATHYTNGGNYTNCAYAGYGTNAARGCNACNACN TAYGCNGCNYTNGCNAGYATHGARGAYTAYYTNGTNGAYTTYCCNTCNGCNYTNAAYTAY ATHGARMGNGCNGTNACNYTNGARCCNATHAAYGCNGARTAYYTNTGGYTNMGNGARAAR YTNTCNAARCARTGYCARGCNATHAARGARCARACNAAYGCNATGAARAARATHGAYGAR AAYMGNYTNACNYTNCCNACNATGGARCARGTNCCNMGNGTNTCNGGNAARAGYYTNAGY GTNTCNGAYTTYCARAAYAARTTYYTNMGNAARGGNAARCCNGTNATHATHACNGAYGTN GTNCCNGAYYTNACNGAYMGNCCNTTYGAYTAYTCNYTNGTNYTNGARCAYGCNGGNAAR ACNMGNGTNACNACNAARGARGCNGTNGCNGAYTCNYTNACNTGGGCNAARYTNGARAGY AARMGNGARACNACNGTNGCNGARYTNATHCARGGNATHCARGARGGNACNGTNAARGAY GTNYTNTTYGAYTGGAGYYTNCCNATHCAYTGYCCNAGYYTNGCNMGNGARATHTCNYTN CCNGAYTAYTTYAARAAYAAYTTYYTNYTNCARACNAGYCCNGGNTCNYTNTAYMGNGAR AGYTGGCCNAGYYTNTTYATHGCNCCNAARGGNGCNACNACNCARYTNCAYGTNGAYGCN TTYCAYTCNCAYTTYTGGATGGCNYTNTTYCARGGNGARAARMGNTGGACNTTYTTYGAY GGNAARGAYACNGCNTTYYTNTAYCCNCARTGGTTYCARTCNACNGAYCCNATHTTYGAR GTNGAYYTNACNMGNCCNGAYGTNTCNCARTTYCCNYTNTTYTCNYTNACNCAYCCNCAR CARTGYGTNYTNCAYCARGGNGARYTNYTNTTYGTNCCNGCNGGNAGYCCNCAYTTYGTN GARAAYYTNACNCCNACNYTNGCNATHTCNTCNAAYTAYGTNGAYCAYTCNAAYTTYAAR AARGTNTGYGARGARYTNAARATHAAYTCNTTYCARGAYCARMGNGCNAGYGAYYTNYTN TCNCARYTNCARGAYCCNAAYTTY------------------AAYCARMGNYTNGTNATH GARTTYTGGTCNGCNGARGGNTGYTCNGCNGCNAAYACNCAYGARMGNATGAARACNGTN TAYGGNGARATGTGYATGTCNAAYTCNNNNGTN------------AARATHTTYAARGGN GARGAYYTNMGNGAYAAYTGYNNNNNNGANNNNNNNMGNTCNGGNMGNCCNNNNTCNACN TCNGAYACNGCNNNNMGNGARAARGCNAAYTGYATGATHMGNGCNAAYCAYMGNGTNAAR CARAARGARATHGCNAAYGARGTNGGNATHTCNAARGARMGNGTNNNNNNNATHNNNACN ACNNNNYTNGGNNNNMGNAARGTNTCNNNNNNNNNNGTNCCNMGNCARYTNACNNNNGAR NNNNNNNNNCARMGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNAARYTNYTNAARTGGAARATGAGYCCNATHACNCCNYTNATHGTNAAR ACNGCNYTNGCNMGNGTNGGNTTYMGNATHACNAARMGNAAYCAYGAYTGGYTNGGNTGY TTYGGNAARCAYATGAARGCNAAYTGYTTYAARCCNYTNMGNGARTAYCARAARYTNAAY CAYTTYCCNGGNTCNTTYCARATHGGNMGNAARGAYMGNYTNTGGMGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNGTNGCNAARAARTTYGCNGTNMGNTAYGCN CAYATHGAYCAYGARGGNAARACNAARGTNGTNACNGGNAARAARGTNMGNACNCCNGAY MGNGAYACNGGNCCNGTNGARTAYGTNTCNGARCCNMGNGAYGTNGTNGARMGNTAYGAR GGNAARGCNGAYTCNGGNGTNTTYGARAGYCARCCNGARAAYATGCCNGAYGTNATHAAR TCNGGNGARCARGCN---CARGAYGCNGTNCCNGARMGNGGNACNGCNAARAAYYTNGCN CARMGNTTYCAYCARATHTCNGTNGARAGYTCNCCNGTNGCNAGYAGYMGNAAYAARMGN GARYTNACNCCNGAYCARAGYGGNMGNACNGARTAYGTNAGYGARCCNMGNACNCARTCN GARACNTAYCARAGYAARGTNGARAGYGGNGTNTTYGARAAYACNCCNYTNGARGAYCCN GARGTNGTNAARTCNCARACNACNAARGARGARTAYGTNCCNGARMGNGGNTAYGCNAAR AAYGTNGCNGCNAARTTYAARGARYTNGARAGYACNGCNAARTCNCCNCCNYTNTCNCCN GGNMGNMGNAARGARTTYACNCCNCCNMGNGARGAYAARCCNAGYMGNACNTCNGGNGTN TAYGARAGYACNCCNGARTCNAARCCNGAYGTNGTNACNTCNTCNGARTCNCARCARGAR GTNTTYGCNGGNGCNGGNACNGCNAARTCNYTNGCNCARMGNTAYAARGARATHGARGCN CARAGYAARTCNCCNGTNGCNTCNAARCCNMGNAARGARATHACNCCNCCNCCNAAYGAR TCNGGNGTNTTYGARAAYAARCCNGARAARTTYCARGCNGARTAYAAYMGNCCNGCNGAR TCNGGNATHYTNGARAAYACNCCNGCNGCNCARMGNGAYGAYGTNYTNAARAGYGGNGAY GGNAAYAARACNGARGTNGARYTNCCNGARGCNGGNTCNGCNMGNAAYYTNGTNAGYAAR TGGMGNCARATHGARTCNGARAGYGCNAARGTNACN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AGYAARATHGAYCARTTYTAYMGNAGYYTNYTNYTNTCNAARTTY TTYACNAARGGNTGGGGNAARCCNGAYAAYYTNAARMGNATHTTYGARTTYMGNAARATH YTNTCNAAYMGNGARTCNTGYCARACNYTNGTNGARAARGAYTAYCCNATHTTYATHGAY AARGAYTAYMGNGAYGGNGAYTGYMGNATHATGGARGGNCAYTTYAARTCNCCNTTYGTN GARCAYATGCCNGGNATHATGCCNMGNGARGTNGARACNGCNAGYTTYCARGCNATHYTN CCNYTNCARTGGCARCAYCCNTCNYTNAARCCNATHTGYATHCAYYTNGCNGGNACNGGN GAYCAYTTYTTYTGGMGNMGNMGNATGTTYACNGCNMGNCCNYTNYTNAARAAYGCNGGN ATHGCNTCNATHYTNYTNGARAAYCCNTAYTAYGGNTCNMGNAARCCNAARGCNCARYTN MGNTCNAGYYTNCAYAAYGTNAGYGAYYTNTTYGTNATGGGNGGNGCNYTNGTNYTNGAR TCNATGGCNYTNYTNAAYTGGTGYGARMGNCARGGNTGGGGNCCNTTYGGNYTNTCNGGN GTNTCNATGGGNGGNCAYATGGCNTCNYTNGCNGCNACNAAYTGGGARMGNCCNATHTCN YTNGTNCCNYTNYTNTCNTGGAGYACNGCNTCNTGYGTNTTYACNCARGGNGTNATGAGY GGNGCNATHCCNTGGCARYTNYTNCARGARCARTTYTTYAARAAYAAYYTNTAYAAYGAY GARATHAGYAARYTNATHGTNTCNCCNGARMGNGCNTAYCARYTNGGNCARCARTTYGTN ATHAAYTAYTAYGCNCARACNAARCARTCNCARCARTCNTCNACNGCNTCNTCNTCNTCN TCNAARYTNACNYTNGGNCAYGCNGTNGCNAARTCNAARATHYTNTTYTCNMGNAARAAR GGNGCNGGNGARGARAARGAYGAYMGNGCNAARAAYYTNCARGARGARTCNTAYGARTTY ATGMGNGGNGTNATGGAYGARTGYACNCAYYTNGGNAAYTTYTCNGTNCCNGTNGAYCCN GARYTNGTNATHATHGTNTCNGCNAARCARGAYGCNTAYATHCCNMGNGARGGNGTNYTN CCNYTNGAYCARYTNTGGCCNGGNTGYGARGTNMGNTAYGTNGAYCARGGNCAYGTNGGN GCNGTNYTNYTNCAYCARGAYGTNTTYMGNAARGCNGTNACNGAYGCNTTYGAYAARCAR ATHCARAARTAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGAAYMGNAGYGTNAAYATHAARYTNATGGCNGGNGCNCCNATGCARAGY TCNMGNGAYAGYGTNTTYTGYAARTAYAAYCAYMGNYTNTGYACNCARAAYTGYYTNGAR GGNTAYAGYTTYTGYATGMGNCAYATHYTNGARGAYAARACNGCNCCNTAYMGNCARTGY GCNTAYATHACNAARGCNGGNMGNAARTGYCCNTCNGCNGCNCCNAARYTNGARAARAAR GARGGNTTYTGYGCNTTYCAYACNAARAARGCNCARTTYGCNMGNCARMGNYTNGCNMGN AARMGNMGNCCNAARGARACNCCNGAYAGYYTNYTNGARGARYTNGTNGTNACNGCNTCN ACNYTNTCNTCNAAYCAYAAYACNGARCCNMGNMGNGGNAARGTNCAYAGYGAYAAYATH GCNTCNMGNGCNYTNGARTAYGCNAGYTCNAGYGAYTCNGARGTNGARCCNYTNYTNGTN GARCAYTCNTGGMGNGAYTCNGGNGAYAGYGAYGCNGARAGYATHGAYAGYGAYCARGAR GAYGTNYTNAARTAYGCNGGNGTNTAYACNACNGARGARGTNGCNCARATHYTNMGNGAY AARYTNATHMGNYTNCARGCNYTNTAYATHGAYCARTTYAARMGNYTNAARCAYGTNYTN TTYACNAARMGNMGNAARTAYYTNCARGCNCARAARAARGARAARGARYTNTTYGGNAGY ATHAARMGNTAYAARGAYGAYCCNTTYCARAARGAYAARTAYMGNAARYTNTGYGCNATG AARMGNTAYCAYAARAARTTYGGNATHGARGCNYTNATGCARTAYCARTCNACNCARMGN MGNYTNAARGTNACNGAYGGNATGGCNCAYMGNCCNCCNTCNCCNATHCARTGYCAYTTY GARGAYGARGGNYTNMGNTGYACNCARACNGTNGTNCCNYTNAGYAARTAYTGYCARMGN CAYATHYTNCAYGAYCARAAYCARGTNYTNTAYMGNCCNTGYCCNTTYGCNGAYAGYCAR TGYGGNMGNCCNGTNCCNTCNYTNYTNGGNAAYCCNTTYTGYTCNYTNCAYCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNMGNGAR CARGTNCARAGYYTNGARGTNGCNGTNGCNGARAARGAYTCNGCNATHTCNCARGCNAAY GARYTNYTNAAYAARCARAARACNGARATHACNGGNATHAAYTCNAARYTNAARGARAAR CARAAYYTNGAYGAYGAYTTYAAYMGNGCNCARGARATGATHAARTCNYTNGAYAARGAY GTNTCNGARYTNAARGTNAGYAAYMGNGAYYTNCARAARGAYATGGARTCNTGYMGNGAR MGNGARTCNAARATGYTNGCNYTNCARTCNGARYTNAGYMGNACNAAYGCNTGYYTNMGN TCNGARAAYACNACNYTNAGYAAYAARGCNACNAAYCARACNGCNGARGTNGARMGNYTN AARATGGARATHCARGARYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARTCNGAR MGNGAYGGNGAYGARACNTTYCARACNTTYATHYTNCAYGAYGARGAYCAYACNYTNGGN AAYGCNYTNAARTAYATHYTNAAYAARAAYCCNGAYGTNACNTTYGTNGGNTAYAGYATH ACNCAYCCNTCNGARACNAARATHAAYYTNMGNATHCARACNGCNGGNAARCCNGCNATG CARATHYTNAARCARGCNTTYAARGAYYTNCARCARYTNTGYGGNCAYATHYTNACNACN TTYGARTCNTCNACNAARTAYTAYAARGARAAYCAYACNGARCARCCNGCNGAYATGGAY CARTCNTGYTTYTCNCCNACNTGYAARAARNNNTTYTCNGTNTTYGAYMGNCAYCAYCAY TGYMGNAARTGYGGNGARGCNTTYTGYCARGCNTGYAGYYTNTAYAARMGNMGNYTNAAY AGYYTNGCNAAYTTYGAYCCNGAYGGNCARYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ACN ATGGGNAGYTAYAAYAARTTYAARAAYGAYTGYATGAARGAYTCNATHTTYYTNGCNATH TGYTGYGARGGNACNAGYGTNTTYGGNGGNTTYGCNATHTTYGCNATHYTNGGNCAYATG GCNCAYATHTCNGGNGTNCCNATGGARGCNTTYACNAARTCNGGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNYTNGCNATGTGGGAYTTYGARCAYTGYGAYCCNAARMGN TGYACNGGNAARAARYTNAGYMGNATHGGNTTYGTNMGNACNYTNMGNYTNAAYCARMGN TTYAAYGGNATHATHYTNTCNCCNGTNGCNACNAARTGYGTNGCNCCNGARGAYMGNAAY ATHGTNGARATGAAYGGNGTNGCNGTNATHGAYTGYAGYTGGGCNAARYTNCARGAYACN CCNTTYGCNMGNATGAARGGNGAYCARYTNMGNYTNYTNCCNTAYYTNATHGCNGCNAAY CCNGTNAAYTAYGGNMGNCCNTGYAARYTNTCNTGYGTNGARGCNTTYGCNGCNACNYTN TAYATHACNGGNTTYGCNAAYGARGCNGARATGYTNYTNGARAARTTYAARTGGGGNMGN TCNTTYTCNTCNYTNAAYAARGARYTNYTNGAYACNTAYAGYMGNTGYAGYACNGGNCAR GARGTNGTNTCNGARCARAARMGNATHYTNGCNGARYTNGARGARGAYGAYMGNCARAAY AARATGAARGAYTGGATGGARATGGAYATGGAYGCNGAYGTNTGYAAYCCNAAYMGNCCN ------CCN---------------------TCNGARACNAGYAGYTCNGARGAYGAYAGY GARGARGARGARAGYGGNGTNGAYGAYGAYGARGARGTN---------CARGCNYTNGGN GARAARATHGGNATGGARTGYGTNACNCARCAYAGYGAYCCNAGYTTYYTNATGGCNATG GCNTCNCAYATGAAYAAYCCNGAYTCNATGGCNAARCCNACNTTYATHTGYCAYTAYCAR AARGARGTNATHAAYATHGTNATGTGYATGAARGAYAARYTNCARGARTGYATHCCNGCN GARTAYCARAARTTYATG---TCNYTNGTNCCNTCNAARGARMGNATGGCNGARGCNYTN GGNTTYGTNTGYGAYCAYAARGAYGTNYTNCARGAYAARTGYATGGAY---GCNAAYATH CARAAYGTNATGCARTGYTAYATGGGNAARGTNTCNCARYTNCARACNATGGCNGCNACN AAYCCNAGYATGGAYYTNGTNAARAARATGYTNTGYGGNGTNGTNMGNTCNGARGARCAR TGYTTYMGNACNTAYCARGGNAGYTGYAGYAARGARTAYATHGARACNATHGTNCARGCN YTNGARATGTTYTTYCCNATGTCNACNTGYCCNAARGCNGAYYTNACNAAY--------- ---ACNATHYTNGGNAGYATHYTNGTNCAYGGNGCNCCN--------------------- ---------------------------------------------------YTNAARTGY CARTAYCCNGAYGCNAARYTNGTNGGNGGNAAYACNGARATHGGNATHGARACNAARTTY AARAAYCARGTNTAYCCNGTNATHATHAGYACNTCNAGYATHCCNCARYTNTCNACNATH CAYACNTCNGARAARGGNATHACNTTYGGNGCNTCNGTNTCNYTNTCNCARGTNGAYTTY GARYTNAARAARYTNATHAARAAYGARACNGGNGARMGNACNAARAARTTYMGNGCNGTN GTNGARATGYTNAARTGGTTYGCNAGYCAYCARATHMGNAAYGTNGCNACNYTNAGYGGN AAYATHGTNACNGCNAGYCCNATHTCNGAYYTNAAYCCNYTNTTYYTNGCNGCNGGNTAY GGNYTNTAYACNATHGARGARGTNAARGTNACNCCNAAYGGNTTYCAYYTNACNCARGGN CCNGGNAAYTAYAARATHCCNTCNTTYGGNAAYATHCCNYTNGARTTYAAYGTNACNATH ATHGARGAYAGYACNAAYCCNTTYGCNGTNTTYGCNTCNAARGGNATHGGNGARCCNCCN YTNYTNYTNGCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TGGGCNYTNGAYACNCARGAYYTNMGNGARGARTAYGARMGNAARYTNAARATHCAR AGYMGNAARTCNTAYAARACNGARCARGTNYTNTCNYTNCARGTNTAYAARYTNCARCAR GAYCARAARACNYTNTCNGARGAYAARGARAARGCNGTNGGNGARMGNGAYTGYYTNAAR ACNCARYTNGARGARGCNAAYTCNGARATHGCNAAYYTNMGNAGYCARYTNGARYTNAAR TCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GCNGCNATHYTNAAYYTNGGNTGYYTNGTNTAYATGYTNCARTGGYTNCCNACNGCN GARTCNYTNGTNCCNTAYTTYGTNATHATGGGNYTNTGGGGNGTNGCNGAYGGNTTYTGG ACNGCNCARGTNACNAGYYTNATGGGNYTNATHTTYCCNGARAARATGGARGARGCNTAY GCNGGNYTNMGNATGACNCARGGNYTNGGNGCNGCNYTNACNTTYGGNTAYTCNAGYGCN YTNTGYATGACNGCNAARATHTAYATHACNYTNGCNATHTGYTCNYTNGGNYTNGTNGGN TAYTTYATHGTNGARTGGATGYTNMGNMGNMGNMGNAAYACNTCNGGNGTNYTNYTNAAR CARACNTCNGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYAARGARGARGARMGNMGNCARAARYTNMGNGAYCARAARMGNGCN CARMGNCARAAYCARGAYTTYGCNGARMGNGARMGNYTNMGNGCNMGNGGNMGNATHAAR GCNYTNMGNGARGAYCCNGTNTTYMGNGARGGNGARMGNCARMGNGAYMGNGARMGNMGN MGNAARGCNMGNYTNYTNAAYCARACNCARMGNATGCARGARMGNGAYMGNGAYAARYTN MGNAARTCNATGATGMGN---------AARAARGCNGGNTAYGCNCARATHAARTCNGAR TTYYTNYTNYTNAAYTAYAARCCNACNATHCARACNGARTAYYTNAGYGAR--------- ------------GAYACNAARAARAARATHGCNGCNGCNAGYGARGARAARCARACNCAY GARGARGAYGAYGCNTCNGAR---------CCNCCNAGYAARAARCCNAARYTNAARGGN MGNAAYAARCARMGNCCNMGNAAYGARMGNATHCARCARAARGAYAARYTNTGYCCNTCN GTNAARAAYGARMGNGARTGYAARTTYGGNGAYAAYTGYAARTTYAAYCAYGAYGTNAAR GAYTTYYTNGARAARAARMGNCCNGAYATHCARGARAARTGYCCNATHTTYGARAARYTN GGNTTYTGYAARTTYGGNATHACNTGYMGNTTYGCNAGYAGYCAYYTNGGNGARAAYCAR GARAAYGTNGTNAAYGARGAYYTNTTYAAYACNATGAARGARAARCCNYTNTTYYTNAAY GCNYTNAGYGAYGAYGTNMGNCAYAARYTNTGGAARMGNAARTAYGAYTTYTCNMGNGCN ATGGAYTCNGTNAAYCAYGTNAAYAARACNTTYMGN------------------------ ------------------------------------------------------------ ------------------GARACNAAYAAYACNACNAAYCCNGGNGARAARTCNGTNCAR GARGCNYTNAAYGGNAARGAYAARGARGTNGTNTCNCCNTCNCCNTCNAARACNGAYGAY ACNGTNCCNACNGTNCCNGARCCNGTNCCNGAYACNCCNAGYGCNGARGAYGTNACNGTN AARYTNGTNGGNGCNGAYAAYGARGAYACNCCNATHMGNTCNACNTCNMGNGARGTNAAR AARATHGAYTTYCAYGAYAARYTNTAYYTNGCNCCNYTNACNACNGTNGGNAAYYTNCCN TTYMGNMGNGTNTGYAARGAYTAYGGNGTNGAYATHACNTGYAGYGARATGGCNGTNGCN TCNCARYTNYTNAARGCNAARGCNTCNGARTGGTCNYTNATHAARMGNCAYCCNAGYGAR GAYATHTTYGGNGTNCARGTNTGYGGNGCNTAYCCNGAYATGATGACNAARTGYGCNCAR GTNYTNGCNGARACNAGYGAYATHGAYTTYATHGAYATHAAYTGYGGNTGYCCNATHGAY YTNATHTTYAARAARGGNAGYGGNAGYGCNYTNATGGGNAARGTNACNAARYTNGARCAR ATHTGYMGNAGYATGMGNGGNGTNATGGGNGARYTNCCNYTNACNGTNAARYTNMGNACN GGNGTNTTYGAYAGYAARAGYACNGCNCAYACNATHATHCCNMGNATGMGNGAYGCNGGN GTNTCNYTNGTNACNATHCAYGGNMGNTCNMGNGARCARMGNTAYACNAARYTNGCNGAY TGGGARTAYATHGAYCARTGYGCNAGYYTNGGNAGYCCNATGCCNGTNTAYGGNAAYGGN GAYATHYTNTCNTAYGARGAYGCNAAYTTYCAYATGTCNMGNAARGGNGTNTCNGGNATH ATGATHGCNMGNGGNGCNYTNATHAARCCNTGGATHTTYACNGARATHAARGARCARMGN CAYTGGGAYATHTCNTCNTCNGARMGNYTNGAYATHYTNMGNTCNTAYACNAARTAYGGN YTNGARCAYTGGGGNTCNGAYCAYCARGGNGTNGARACNACNMGNMGNTTYYTNYTNGAR TGGYTNTCNTTYYTNCAYMGNTAYATHCCNGTNGGNGTNYTNGARCARGTNCCNCARAAR ATHAAYGARMGNCCNCCNTAYTAYATHGGNMGNAAYGARYTNGARACNYTNATGGCNAGY GCNAAYTGYGCNGAYTGGATHAARATHAGYGARATGYTNYTNGGNCCNGTNCCNTCNAGY TTYCARTTYYTNCCNAARCAYAARGCNAAYGCNTAYCAR------TCNAAYACNCARCAY ACNGARTGGATHYTNGAYACNATHGAYCAYYTNMGNAARMGNAARGCNMGNCCNGAYYTN CARMGNATHTGYCAYGTNGTNMGNMGNMGNTAYGGNYTNCCNAGYGCNGTNACNGARGCN AARYTNGARAARYTNGTNGAYGCNGARATHGTNATHAARGTNGARTAYAARGGNAGYACN AGYTAYMGNAAYGCNTCNAARTGGAARMGNAAYYTNATHGGNTGYACNYTNCARAAYTCN ACNACNGTNTCNACNAARATHATHGARGCNATHYTNGCNYTNTCNAARAAYAARACNCCN TCNGAYAAYGGNAAYAAYGCNCCNGGNACNTTYGAYAARGAYGGNCCNTCNTCNGCN--- ---------------AARGGNAARTGYCARGAYGGNATHTCNYTNGARGAYATHGARGCN TGGYTNAARAARCAYTGYGAYGCNTTYACNAAYYTNAARAGYTCNYTNAGY--------- ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGAARACNCARMGNGGNAARACNMGNAARAAYGTNTCNTCNCCNAGYTGY YTNGARCCNGTNTCNGTNTAYTGYMGNATHMGNCCNYTNGAYGAYCCNAAYGARCCNACN TGYATHAARCCNYTNAGYGAYACNGTNGTNCARYTNCARACNCCNGARAAYGCNCCNTCN MGNAAYGGNCARATHAARGARTAYCARTAYACNTAYCARCAYGTNTTYGAYGARTGYACN TCNCARAARACNYTNTTYGAYAARACNGCNYTNCCNGTNGTNGARGAYYTNYTNTGYGGN AARAAYGGNYTNYTNTTYACNTAYGGNATHACNGGNTCNGGNAARACNTAYACNATGACN GGNGTNCCNCAYGAYCARGGNATHYTNCCNMGNTGYYTNGAYGTNYTNTTYAAYAGYATH GGNGAYMGNCARGCNAARAARTAYGTNTTYMGNCCNGAYCAYATGAAYGGNTTYGARGTN CARAGYGARGCNGAYGCNATGATGGARMGNCARAARAARGAYATHATGCCNGGNYTNACN TCNGGNAGYAARACNTCNYTNAARMGNGGNGAYAGYGGNGAYACNGARMGNATHGTNGAY CCNACNACNGTNGARGGNGTNGARGAYGAYAAYAAYTAYTCNGTNTTYGTNTCNTAYATH GARATHTAYAAYAAYTAYGTNTAYGAYYTNYTNGARGARYTNCCNTAYAAYACNATHACN GGNTAYMGNCCNCCNCARACNAARATHYTNMGNTCNGAYTCNTCNGAYAAYATGTAYGTN CAYAAYTGYACNGARGTNGARGTNAARCARCCNCARGARGCNATHGAYGTNTTYTAYAAR GGNCARMGNMGNMGNAARGTNGCNCAYACNGCNYTNAAYGCNGARTCNAGYMGNAGYCAY AGYGTNTTYAAYATHMGNYTNGTNCARGCNCCNYTNGAYAAYMGNGGNGARGARGTNGTN CARGAYTCNAAYMGNATHTGYGTNTCNCAYYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GARTGYTCNMGNYTNMGNTCNAARYTNGARGAYATGAARAAYGARAAR GARGTNATHAARGARGARTTYCARTTYYTNATHGGNAARAARGARGGNCARGGNGAYCAY YTNTCNAAYYTNAARGAYYTNACNTTYAARCAYATHTTYGARGARGARYTNMGNGTNMGN CARAARYTNGARGARGAYGAYAARATHATHCARGARYTNAARGARTAYATHGARAARYTN MGNAGYGARMGNAARGARYTNAARGARAAYGTN------------MGN------------ ---------TCNYTNAARTCNGARAARATHGARTCNGARTCNYTNYTNGARACNGCNGAR AAYGARAARGCNAARTTYATHCARCAR------------------------------YTN GCNGAYTAYACNGCNGGNYTNGARAGYAARGARTCNGAYYTNYTNGARACNAARAAYGAR YTN---AAYATHYTNAARAAYGARYTNGARAARYTNCARAGYAGYTTYGCNGARYTN--- ------------------------------------------------------GARAAR GARAARYTNGARCARGARAARAARTAYACNTCNGARYTNAARACNGGNCARGARGARATG ACNTCNGARYTNGARMGNYTNAAYGARCARGTNAARGAYGTNGARGARYTNACNACNAAR AGYGARATGTAYAARGARGARGTNAARTCNATHAARGCNCARGTNTCNCARYTNGARGGN ATGTGYCARGARAARGAYAARGARATHGARTCNGTNAARGARMGNATGACNMGNTTYGAY CARGAYYTNTCNGARATGGARGARTCNGTNCAYATHACNCARCARYTNAGYGAYTCNGAR ATGCARAARAARGARGGNGARATHGGNGARYTNAARGCNGCNAARGARGARYTNGARACN MGNATGAARCARATGCAR---------------ACNCARATHGCNTCNYTNAGYGAYCAR CARGTNTTYGARGAYGARATHGAYGCNYTNAARAARGARMGNGAYGGNAAYAGYMGNACN ATHTCNCARYTNGARACNGARYTNTCNGTNTCNGARGARAARATHACNAGYYTNMGNCAR GARYTNYTNGCNGCNGTNAAYTCNACNCAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CCNCAR--------------- ------GCNTCNAAYAARGAYAAYCARTCNTCNAGYAARGGNAAYGARGTNMGNGCNGAR GAYGTNATGGARATGGCNGTNGCNAARCCNYTNYTNGGNTCNTAYCAYCAYGAYGAYAGY CARGAYACNGAYTAYATGGAYMGN------------------------------GAYCAR GAYMGNTTYGCNGARYTNGARAARGARATGGARGARYTNMGNGGNMGNYTNATHGARAAR GAYGGNATHGTNTCNGAYYTNCARMGNTCNAAYTCNTCNYTNYTNGARYTNYTNGARAAR AARGCNGAYGGNGAYAGYAGYTGGGGNAAYMGNYTNACNAGYCAYAARYTNGARGCNGAR YTNAARGCNYTNMGNGTNGARMGNGARCARATGGTNGCNGTNGTNAGYGARAARTCNMGN GARAAYTCNTCNYTNAARTCNGARATHCAYMGNYTNATGGAYYTNGTNGCNGCNGGNCAR GCNGCNYTNGCNAARGTNCARCARGAYAAYGTNTCNYTNGARCARMGNCARCAYTCNCCN CCNMGNGAYGAYGAR---GARGARGAYAGYATGAARMGNGARGCNYTNAAYAAYATGGCN MGNYTNGTNMGNGAYAARGAYACNGARATHGARGCNYTNACNCARAARAAYAAYACNYTN YTNGCNGTNYTNCARGAR---TCNAAYGARTCNAGYGCNGCNGCNCAYYTNGGNCCNYTN YTNAARGARAARGARACNYTNACNCARCARATHAAYTCNATGYTNACNGARMGNGARCAR YTNATHACNTGYGTNACNCARAARCAYTCNGARTCNYTNGCNTTYCAYGCNGARGTNCAR MGNYTNTCNGGNYTNYTNGTNGARACNCARGCNGTNGCNGAYGARGCNAARGCNGARTTY GCNGCNYTNATHCCNTCNTTYGARGGNAARAAYCARGCNYTNYTNACNGCNCARCARGAR YTNGTNGARTGYAARCARAARYTNMGNGARATHGARATHMGNCAYGGNGARYTNATGACN CARCARTCNAGY---------------CAYCARCAR------------CARGCNACNGAY GAYYTNGARGCNGARYTNGARAARTAYAARMGNYTNGARTCNGAYTAYAARTCNATGGTN ATGGARMGNGAYGARCARATHCARAGYYTNTCNCARAARTCNAARACNTTYGARGAYGCN ATGTCNTCNMGNGARGCNGARTGYACNCAYYTNMGNAARCARYTNGARAAYTCNAARTTY CARYTNACNGGNYTNATGGCNGARATHGCNGAYGTNAARTCNGARMGNGARGAYATHCAR CARAARACNGCNATGCARGGNGARGARTCNGTNAGYYTNMGNAAYGGNYTNAAYCARATG ACNYTNGTNYTNAARGAYAARGARGCNGARATHGTNTCNYTNAARGAYCARATHTCNACN YTNAAYTCNGTNYTNCARAAYCARAARGGNGAYGARGAYCARGTNMGNCARYTNATHMGN GAYCARGARTCNGCNGTNGCNGCNAGYMGNCARYTNCARCARGAYMGNGAYMGNAAYGCN ATGYTNGCNGARCARMGNTTYCARGARTGYGARGCNYTNAARGCNGARYTNTCNACNCAR AARGAYAARATHTTYAARATGGGNMGNGARYTNGARMGNYTNMGNGGNCAYYTNATHGAR ATHGARGARGGNTAYACNAARGARGCNYTNGARTCNGARGARMGNGARAARGARYTNMGN AAYAARYTNGCNGTNGCNGARGARCARYTNATGAGYTCNTCNTCNCAYGTNCARYTNGCN AGYCARGARTCNGCNMGNCARGTNGARAGYYTNCARGARCARYTNCAYCAYATHGCNTCN CARMGNGAYGCNGCNTAYATGCARGTNGCNACNAGYCARGAYCARTGYCARCARTAYGCN GCNTCNYTNAGYAAYYTNCARYTNGTNYTNGARCAYTTYCARAARGARAARGAYTCNGCN ATHGCNYTNGARACNGARAARTAYCARGAYCARGCNAAYMGNYTNAGYACNAARGTNAAR GARGTNGARAARGARYTNGARGCNACNMGNGGNGAYYTNGCNGARGCNYTNGAYGGNYTN GARGCNGCNTCNMGNYTNAGYGARCARYTNGAYMGNAARGARGARGCNYTNATGGCNYTN AARGARGARGTNYTNYTNMGNGARCARGCNYTNAARGGNGCNGARGARGARATHGCNAAR YTNAAYTCNAGYAARGARGCNAARGTNGAYAARATGYTNATGCAYAAYATGGTNYTNACN TGGYTNACNTCNCCNGARAARAARMGNCAYGARATHGTNCARYTNATHGGNCAYGTNYTN GGNTTYAGYCARGAYGAYTTYTCNAARATHGARTCNGCNCAYAGYCARGAYAGYYTNTGG ATHGGNTTYTTYAARMGNCCNAARTCNCARCCNACNACNCCNACNAARAGY------GAY CARTCNTTYTCNCARYTNTTYGTNAARTTYYTNGARAARGARTCNTCNCCNTCNCCNGCN CCNGTNCARYTNCCNGTNGARGCNATGGCNGCNGARGCNCARCARMGNCAYAARACNGCN TTYAAYCCNTTYATGGCNCCNMGNCAYGTNACNCAYCAYAGYGGNAAYGARGCNTCNTCN TCNGGNTCNTCNTCNCAYYTNYTNATGCCNCARGAYTCNGCNCAYCCNTCNCCNYTNTTY GCNCCNGTNACN------AAYAGYGCNAGYGARAGYGCNATHYTNAARGAYGTNYTN--- ------------------------------------------------------------ ---------------------------------------------CARCAYYTNCAR--- ------CCNGCNGTNGCNGAYGARGARGGN---------TCNATGAAYCAYACNATGATH ATHATHGTNACNTCNGTNGCNGTNGTNYTNYTNTGYYTNGCNGCNGCNYTNGTNTTYATH YTNCAYMGNMGNYTNMGNGGNAARAARMGNGGNYTNGGNTCNYTNATGTCNGARAAYMGN YTNYTNGARGARGARGGNTCNGGNTCNAARGTNTTYGGNGAYCAR---TCNTCNGGNAGY GGNTCNGGNCARGCNAARYTNGTNAAYMGNACNGTNGGNAARGARGTNCAYYTNATHGAR AARATHGGNAAYGGNMGNTTYGGNGAYGTNTGGMGNGGNAARTGGYTNGGNGAYGAYGTN GCNGTNAARATHTTYACNTCNYTNGARGARACNAGYTGGMGNCARGARATGGARATHTAY AAYACNGGNATGYTNAGYCAYGARAAYATHYTNGTNTTYCAYGCNTCNGAYACNATHGGN MGNTTYTCNTGYACNCARAAYYTNYTNATHGTNCARTAYCAYCCNAAYGGNTCNYTNTAY GAYTAYYTNATGMGNMGNGAYATHGAYATGGARGARATGYTNATHYTNGCNAGYTCNGCN GCNGCNGGNATHAGYCAYYTNCAYTAYGARATHAARCARGGNACNGGNACNCAYGARAAR CCNTCNATHGCNCAYMGNGAYATHAARTCNAARAAYATHYTNGTNAARYTNAGYGGNGAR TGYTGYATHGGNGAYYTNGGNCAYGCNGTNAARAAYACNAARGARYTNGTNGAYAARGGN MGNGGNYTNTGGGTNGGNACNAARMGNTAYATGGCNCCNGARYTNYTNGCNAARACNYTN AAYCCNGCNCAYTTYGARTCNTTYMGNTGYGCNGAYGTNTAYGCNTTYGGNYTNGTNYTN TGGGARATHGCNMGNMGNGCNMGNCCNTAYTGYGAYGAYTAYMGNGTNCCNTTYTGGGAY ATGGTNCCNGCNGAYCCNAGYATHGARGARATGAARGARGTNGTNGTNGAYCARMGNMGN MGNCCNGCNATHCCNAAYAAYTGGGCNCARGARCARYTNATGGTNGARATGGARAARYTN ATHYTNGGNTGYTGGGCNCARAAYCCNTCNTGYMGNYTNAAYATHYTNMGNGTNAARAAR AAYYTNCARGCNYTNYTN---TCNMGNAAYGARCARATGATGGARAARMGNGARMGNYTN ACNGGNAARATHYTNGAYGGNAGYACNACNACNAAYAGYATGGTNACNACNTCNAGYAAY ATGYTNTTYAAYYTNGARGAYTGGAARCARGGNATGGAYYTNYTNTGYGARGAYYTNAAY MGNAARYTNGTNTTYMGNAARCAYTTYGAYTGYYTNTCNMGNTTYGCNCCNMGNATHTCN GGNTGYATHYTNATHMGNACNCARATGTTYAARAARGCNATHYTNGAYGCNGGNATGGCN ACNCAYCARACNYTNCAYGAYATHACNTGYAAYTTYGCNGARAAYATHGTNAAYTGYYTN GARMGNCCNYTNGGNMGNCARTGYCCNATHAAYGTNGTNGAYACNATGGTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TTYATHCCNTCNAAYTTYGAYYTNYTNGGNGAYTTYTGYTCNGTNGAR CARYTNGARYTNGGNAGYATHYTNACNGAYAGYGAYYTNATHGARYTNCARCCNTCNYTN GGNGCNGARGGNYTNAGYCARACNGGNATHGTNGCNGGNTAYGAYGGNYTNGAYGCNGAY GGNACNYTNGCNCARGCNGCNGCNGTNAAYTCNTGYCCNACNGGNAARTTYCAYGGNAGY GGNGTNGGNCAYGGNGGNATHATGTCNGTNCARGAYGARATGTGGMGNAARGARMGNATH AARAARGAYAAYCAYAAYATGATHGARMGNMGNMGNMGNTTYAAYATHAAYGAYMGNATH AARGARYTNGGNGGNYTNYTNCCNAARAGYATGGAYCCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGYTNCARAAYMGNATGAAYMGNYTNCARGAYGCNYTNAAYGCN TAYGGNCCNAAYTCNCARCAYTTYYTNAARGAYTCNGTNGTNAGYCCNTGGGARMGNGCN GTNGCNGTNAAYAARGTNCCNTAYTAYATHAAYCAYGAYACNGARACNACNCARTGGGAY CAYCCNCARYTNACNGTNATHATGGAYCARYTNATHGAYATGAAYAARATHMGNTTYGCN GCNTAYMGNACNGGNATGAARYTNMGNTGGYTNCARAARGARYTNCAYYTNCAYACNGTN ACNYTNCCNATGGCNATGGARTCNTTYGAYAGYCAYGGNYTNMGNGGNMGNAAYGAYAAR YTNATGGAYGTNGGNGARATHATHGARTGYYTNTCNTCNATGATGGARTCNGCNGCNAGY CARCAYCCNGAYATGGTNAAYGTNCCNYTNTGYGTNGAYYTNACNYTNAAYTGGATHYTN GAYGTNTAYGAYAGYGTNMGNAGYGGNAARATHMGNGTNYTNTCNTTYAARGTNGCNGTN GTNYTNYTNTGYCARGCNCARYTNGARGAYAARTAYMGNTAYATHTTYMGNYTNATHGCN GAYACNAAYGCNTTYGCNGAYCARMGNAARATGGGNYTNYTNYTNCAYGAYTGYATGCAR ATHCCNMGNCARYTNGGNGARATHGCNTCNTTYGGNGGNAGYAAYATHGARCCNAGYGTN MGNAGYTGYTTYGARAARGCNAAYAGYMGNCCNGARATHGARGCNTAYCAYTTYYTNGAY TGGYTNAARYTNGARCCNCARTCNATGGTNTGGYTNCCNGTNYTNCAYMGNGTNGCNGCN TCNGARACNTCNAARCAYCARGCNAARTGYAAYGTNTGYAARGAYTTYCCNATHYTNGGN TTYMGNTAYMGNTGYYTNAARTGYTTYAAYTTYGAYGTNTGYCARAAYTGYTTYTTYTCN GGNMGNACNTCNAARAGYCAYAARYTNGCNCAYCCNATGCARGARTAYTGYACNACNACN ACNTCNGGNGARGAYGTNMGNGAYTTYTCNAARGTNTTYAARAAYAARTTYAARTCNAAR MGNCAYTTYAARAARCAYCCNMGNMGNGGNTAYYTNCCNGTNGAYTCNCAYYTNGARGGN GAYAGYYTNGARAGYCCNAAYCCNTCNCCNCARCAYAGYATHTCNCARGAYATGCAYTCN MGNYTNGARATGYTNACNAGYMGNATHGCNGARGTNGARCARMGNCARGGNGGNCCNGCN GAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ACNMGNGTNAGYMGN ACNYTNGAYTAYYTNCAYYTNTGGAARAAYAARGTNAARTCNTGGAARTTYTGYAARAGY CAYCARGTNMGNYTNATHAARATGGTNTAYAAY---CCNGARYTNAGYGAYGGNGAYTTY GARACNTGYYTNGARTAYTTYGARAARGTNCARGGNAARGCNMGNGARYTNYTNAARTCN GAYGCNATGGCNGTNATGGCNGARGGNGARGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGGCNGCN CCN---ATHCARMGNAARCCNYTNCCNTGYGAYGAYATHCARMGNTTYCARGAYACNYTN AARAAYYTNMGNATHATGGAYGAYMGNATHATHCAYGCNYTNAAYAARAAYATHCCNACN CARTCNTTYCARGGNAAYGTNGAYGTNGCNTCNAAYTGYAARCAYATHTAYGAYGAYYTN CARACNTCNTAYAGYCAYMGNGARAARTCNATHCARCAYTGYATHMGNYTNGTNAGYGAR GAYGTNAARAARYTNAAYGAYAARMGNCARAAYGAYCCNGAYGAYYTNGAYGTNATHAAR AAYYTNMGNAARGARCARACNAARYTNMGNYTNATGCARCARGARATGAAYGTNGARGAR GTNGTNAARGAYMGNACNYTNAARGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNGTNTGY ACNATGGCNAARCCNGTNAAYMGNAARCCNCAYCCNGGNGAYCCNGTNGARGGNGAYTCN CCNGARCAYAARCCNGAYGARGCNYTNGGNYTNGCNTAYGARCAYTAYYTNAARGARGTN GTNGAYGTNYTNGARAGYGAYGCNGCNTTYAARAARAARYTNGARACNTCNAAYGTNACN GAYATHAARAGYGGNAARATHGCNATGTAYYTNGARYTNGTNAAYCAYACNGTNMGNGAY ATGYTNCAYGARYTNAARMGNAARGARYTNGCNMGNYTNTCNCARYTNGCNMGNATHCAR ATGAARTCNCARTCN------AARAARTTYGARATHCCNGAYCAYYTNGAYYTNGGNAAY CARCAYACNTTYGARATHAARGAYYTNGARMGNYTNATHAARAARACNACNTCNGAYYTN GARAARYTNGAYGARCARMGNMGNGARGARTTYAARGARTAYGARATGGARAARAARTTY GARCARGARGARCAYYTNAARGARYTNAAYGARGCNGAYMGNAARAARGARGARGARCAY CARGCNGARYTNAARAARAARCAYAARGARCAYCCNAARGTNAAYCAYCCNGGNAGYAAR GAYCARTTYGARGARGTNTGGGAYCARGAYGAYCAYYTNGGNGAYATGGAYTTYGAYCCN AARACNTTYTTYATGACNCAYGAYATHAAYGGNGAYTTYGARTGGAGYATHGAYGARGTN GAYGCNGTNYTNCARMGNGARYTNGAYAARGTNTAYGAYCCNAAYGGNGAYCCNCARGAR GAYGAYCCNATHGARMGNGAYGARGARATGAAYMGNATGMGNGARCAYATHTTYACNGAR ATGGAYMGNGAYAARAAYYTNMGNATHTCNYTNTCNGARTTYYTNGCNTAYACNGGNCAR CAYGGNGARAAYAARGARTTYCARAARGAYGARGGNTGGAARACNATHGAYGARGARCCN GTNTTYGAYGARGARGAYTAYYTNAAYTAYATHAARCARCAYCAYCCNCARCCNGGNGTN GTNGAYCCNCCNGAYCCNAAYYTNCAYTTYCARCCNGARCARCAYCARCARCARCARCAR CARCAR------------------------AGYAGYMGNATHTCNATHATHAARMGNMGN ATHGARGAYYTNAARMGNGGNGCNAARCARMGNAARYTNGAYGGNACNGARGTNGCNGCN CCNCCNAGYGARAAYAAYATHGCNGTNGAYAARYTNTCNGARGARMGNYTNMGNYTNCAY GGNGTNAARGTNYTNTCNGCNGARGAYMGNGCNAARAAYTCNGTNYTNGAYATHGAYACN GTNCAYAAYTAYTGYGCNAARYTNTTYGTNTTYAARACNATHGTNGTNAARAARTAYMGN ACNTGGMGNGARMGNMGNAARCAYYTNATGGCNAARCAYMGNCCNGCNMGNCCNGARYTN CCNTCNGAYACNAARYTNATHACNTGYCCNATHGTNTGGAARAAYTCNCAYTCNAAYAAY TCNGGNAARAARAARGARTTYGTNYTNAAYCCNTCNGGNAARTCNTAYYTNTGYATHYTN CAYGARTAYATGCARMGNACNYTNAARATGCARCCNACNTAYGTNTTYAARGARYTNGAR AAYCCNAARACNCCNTAYGGNGCNACNGTNAARATHAAYAAYATHGARTAYGGNACNGGN YTNGCNTCNTCNAARAARATGGCNAARCARGARGCNGCNAARGARACNYTNAARATHYTN ATHCCNGGNYTNTGYTCNAARATHTCNGAYCARGARYTNAARAAYACNGTNACNGAYYTN TCNTTYTTYGAYGARATHCARGTNGARGAYCCNMGNGTNAAYGAYYTNGGNAAYAARGTN GGNCARCCNAGYCCNTTYCARYTNYTNMGNGARTGYYTNMGNMGNAAYTTYGGNATGGGN ACNCCNCARTGYACNATHAAYACNACNGCNYTNAARAAYCARAARTGYGARTTYTCNYTN TCNGTNGGNAARCAYTCNGCNACNATHATHGCNAARAAYAARMGNGAYGGNAARCARYTN GCNGCNCARGCNATHYTNGCNAARYTNCAYCCNCAYGTNCCNAGYTGGGGNTCNYTNYTN MGNYTNTAYGCNACNAAYGTNGARAARCCNATGGARAARGTNGARGARATGAAYGARATH AARACNCAYGTNCCNAAYAARGCNGTNYTNGARAAYYTNMGNAARGARATGMGNAARYTN CAYAARCARAARGARGCNATHCARTCNAARGGNAARATGYTNATHTCNACNAARGAYYTN CCNAGYAARATGTCNTGYGTNGAYYTN------GCNTTYGGNYTNCAYYTNGGNGCNTGY TCNGCNTGYYTNGCNGTNCAYMGNGAYGGNAARACNGARGTNATHGCNAAYGAYYTNGGN GAYMGNGTNACNCCNACNGTNGTNGCNTTYACNGAYCAYGAYATHTCNGTNGGNGCNGGN GCNAARCARGGNGCNATHMGNAAYGCNGCNAAYACNATHGCNCAYGTNAARCAYATHGTN GGNAGYGAYAGYGARGAYGGNCCNGTNAARGARTAYATGCARAAYCAYCARGTNGAYGTN GCNTGYCARAARGGNTCNATHATHTTYAAYGTNGARCAYYTNGGNAARAARGTNCARTAY ACNCCNAGYAARGTNYTNGARYTNATHTAYAAYAARATGYTNGARACNGCNCARAGYCAR GTNGGNAGYGGNGARAARGAYGCNGTNYTNGCNGTNCCNTCNGAYTTYACNCARCARCAR MGNAAYATHYTNAGYGARGCNGCNACNAARGCNGGNTTYAARGTNYTNMGNATGATHAAY GARCCNTCNTCNGCNATGYTNGCNTTYGAYGTNGGNCARTTYGAYGARTCNGARCARGAR TTYAARACNYTNGTNTAYMGNATHGGNGGNACNTCNCAYGAYGCNACNYTNGTNAGYGTN CARCAYGGNATGTAYTGYATHGTNGCNAARGCNTCNGAYAAYCARTTYGGNGGNGAYAAR YTNACNGARGTNYTNCARGGNYTNYTNGCNTCNGARTGYAAYMGNCARYTNMGNTGYGAY GTNACNGARAGYAARMGNTCNATGAGYAARYTNAARYTNGCNGCNGARMGNTGYAARCAY TCNYTNAGYTCNYTNTCNAAYGCNCARTGYAGYGTNGARTCNGTNTTYGAYGGNYTNGAY TTYTCNTAYAAYGTNTCNMGNGCNMGNTTYGARAGYCARTGYATGCCNCAYATGTTYCAR TGYACNCARYTNGTNCARCARGCNYTNAAYAGYGCNGGNTGYACNAARGARGAYATHTCN AARGTNATHYTNTGYGGNGGNGGNGCNAARTCNCCNATHGTNAARAARGTNYTNACNGAY TTYYTNCCNTCNTCNTCNATGYTNAAYTCNATGCCNGARGAYGARATHATHGCNATHGGN GCNGCNAARGARGCNGCNYTNYTNGARGGNGAYGAYGARGAYGAYAARAARGTNCARAAR CARGARTCNAAYGCNTTYAARTCNYTNTCNAARGCNATHTGYYTNMGNGTNAAYTCNCCN GARYTNCARGTNATHYTNCCNCARCAYTGYYTNATHCCNACNMGNMGNCARCAYACNYTN ACNYTNCCNTCNACNCARTCNTCNGTNAARYTNGARATHYTNCARGCNCAYGARCCNATH ACNGCNGAYACNGARGCNCARYTNYTNGCNAARATHGTNYTNMGNGAYYTNCCNCCNGGN TCNAGYATHAARTCNAGYTTYCAYYTNACNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARGARGAYGARGAYGAYGARGARGAYGGNGGNMGNGGNGAYGARMGNGARGAYGTN GGNTCNMGNGCNAGYGGNGARTCNGGNCCNTCNGARGGNGCNGARACNGAYGAYATHCCN ACNGTNGCNGTNCAYATHGGNCCNGGNGAYGAYGTNGAYATHGARGGNAGYTCNYTNMGN TCNGCNTCNCCNAARAARGTNMGNTTYGARGARAGYGCNGCNACNTCNGGNTAYATHMGN CCNCCNATGMGNGAYGGNACNACNTGGACNGGNCARCCNGAYTAYGAYMGNTTYYTNTTY ATHMGNATHTTYTGYCCNGARGGNYTNGARCARYTNGGNACNGGNATHAARTGYTCNYTN TCNTAYGAYGGNAAYATGTTYAARACNCCNATGYTNGAYACNCCNGAYGAYGAR------ GARTCNGARATGACNGARGARGTNGGNGARMGNCCNAGYCARMGNCCNCARGCNGCNMGN AARGCNGARTGYMGNTCNAAYGCNGAYGTNACNCARGARACNGAYTCNGCNAARTCNAAR ACNAARAARTAYTTYGARTTYGARATHCCNYTNCCNGAYGARATHYTNGARGGNATHYTN YTNYTNGGNGARAARCCNGCNGCNGARCCNGARAAYATHMGNGTNGCNATHCAYCAYGGN CARTTYGARGARATHATHGCNATGGCNACNATHGAYTTYCARGAYATHAARGGNYTNAAY YTNGARACNATHTGGYTNCCNGCNCCNACNGGNGAYGAYGAYGTNGCNGTNGCNAARTCN MGNTCNAAYTCNYTNAGYGGNGCNTCNAGYYTNGGNGGNGARTCNYTNTCNGAYTCNATG GAYATHCCNATHATGATGGAYGAY------GAYCARTCNGGNMGNGGNYTNGTNTCNTCN ACNCCNMGNGAYGAYATGTTYAARGTNAARGAYCCNYTNCCNTTYCCNYTNTAYCCNYTN CAYGGNGGNAARACNGAYTCNYTNCAYGTNCCNTGYGGNAAYGTNCCNYTNTTYYTNTAY TGGGCNAARMGNCCNMGNCCNYTNCAYTTYAAYMGNCARTGYGGNACNYTNGGNATHTAY GAYATHGTNTAYGAYATHACNGGNTAYGAYATGACNACNACNACNAARGARGAYYTNCAY AARGARATGGTNGAYGARGCNYTNTCNGTNGCNGCNTTYACNCCNGAYCCNGAR------ ------------------AARGARACNGTNYTNAARTCNGARTAYGAYAARATGGTNGAR MGNCAYCARGARGARATGATHTAYYTNCARGARGARTAYGARAARMGNYTNCARGARYTN ATGCARAAYYTNCARACNATGCARGCN---------GARAAYGCNGARCARGTNCCNCAR YTNATHTCNCARCARMGNCCNYTNTCNCARGCNTCNMGNGCNAGYACNACNCCNGGNGCN ATGACNCCNATHACNTCNAARMGNTCNGARMGNTCNGAYCCNTCNTTYTTY--------- GARYTNCCNCARACNGGNCARAGYATGMGNACNTTYAGYMGNGAYAARACNAGYATHGGN GARATGGARMGNGARAARAGYATGGTNTCNCARAGYACNGCNAGYACNMGNYTNAARCCN YTNCCNCCNMGNAGYGTNMGNCARAAYMGNAAYTTYMGNATHGGNAARCCNAAYCCNAAR TGGGGNGARACNYTNCCNCARGAYTTYTTYGAYMGNYTNMGNYTNTGGGARGARGARMGN MGNCARCAYCARCARGARYTNAAYGARAARACNYTNAARGAYATHAARGAYAAYYTNGAR AARAARYTNGCNGGNCARCAYAARYTNAGYAARMGNGARGARCARATHTAYGAYGCNYTN AARGAYGTNAGYYTNCCNGCNYTNTTYATGCCNTAYAARACNGGNAAYATHTTYAAYCCN MGNGCNCAYCAYTAYTTYCAYCCNACNGGNTCNTCNGAYGTNMGNYTNACNCARCCNCCN TCNGTNTTYTCNYTNCCNCCNYTNCCNAAYAGYAARYTNTCNGTNGTNAAYYTNTTYGAR YTNAGYAARAAYTTYMGNAAYMGNGGNCCNGCNTGGYTNGTNGARMGNTAYATHCARCAR CARCARCCNTCNCAYGARGAYTAYCCNCARACNCCNGCNCCNACNTCNGCNGTNAARCAR GAYACNACNACNTCNGGNCAYACNCCNATHAAYGARAAYGTNGCNACNCCNACNAGYCAR ACNAGYATHCARCCNGARYTNGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ACNGTNACNTTYATHYTNAAYMGNGAYAAYCCNGAYAAYCAYCARTTYGAYATHGARATH MGNGTNAARCCNGTNATHGGNGGNATHGAYCCNGGNGGNGGNTAYAAYTAY--------- TTYAGYTTYCARAARTTYGARCARGARGCNATHGTNGGNATGATHMGNGGNTTYTAYGGN YTNGTNATHATHATHTGYATHGCNGTNGTNTGYTAYTGYAAYATHMGNTAYMGNGGNYTN AAYAARAARTGGGARACNCAYCARYTNGCNACNATGAARACNGAYACNACNTTYGAYGGN MGNAGYCARATGTCNCAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARAAYTCNCCNCCNATHAARATHTCNAARATGGARAAYGTNATHCARACNGARTAY CCNAARYTNGTNGGNGARYTNGTNCARGCNYTNCCNCAYGTNCCNYTNACNTCNTTYGTN GARTGGTTYATHGARACNTCNTAYCCNGGNCARTTYGGNGGNTCNGARGARTCNATHTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNTCNMGNATGCARATHTTYAAYMGN AAYGGNCAYTTYYTNMGNMGNATHGCNATHMGNTTYATHGAYATHGTNGCNGGNYTNGAY ATHACNCCNGARGGNCAYATHGTNGCNGTNGAYAGYGTNTCNCCNACNGTNTTYMGNYTN ACNGARGCNGGNGARYTNATHAARTGGTTYGAYTGYAGYGAYTAYATGMGNGAR------ ------------------------------------------------------------ ---------------------------------------------------------AAR GARAAYMGNTTYAARMGNACNGCNGARGCNYTNCARAARTCNGGNYTNTGGGAYATHGCN ATGAARACNGGNCAYYTNATHAARMGNAAYCARGARYTNCARAARGARYTNGARCARTTY AAR--------------------------------------------------------- ------------------------------------------------------------ ---------------------------------CCNGAYMGNTGGGARGCNTAYACNAAR ATGGGNAGYGTNATHGARGGNACNACNATHATGCCNATHAARGTNCCNYTNMGNGARAGY YTNACNAGYTCNYTNGCNTCNGAYGARMGNTTYCCNCCNTCNGCNYTNYTNACNYTNATH CARGARAARAAYYTNAARYTNTGYGGNGTNGTNGAYYTNACNTAYACNACNAARTAYTAY GAYTCNYTNTTYTTYMGNCARAAYGGNGTNGGNTAYAARAARGTNTTYACNGCNGGNCAY GTNATHCCNACNGAYAARAAYTTYGAYCARTTYGCNAGYGCNATHCARGCNYTNGARAAR GARGGNGARGTNATHTGYGTNCAYTGYACNCAYGGNYTNAAYMGNTCNGGNTAYATGGTN TGYMGNTAYATGATHGARTTYYTNAAYATHGAYCCNCARGCNGCNATHMGNYTNTTYGAR CARGCNMGNGGNCAYAARATGGARMGNCARAAYTAYATHGAYGAYYTNYTNAGYMGNGCN CCNGGNGTNAARGGNCCN---GARGAYCCNAAYTCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNATHGTNYTNGAYGARGARAAYGGNGTNTTYCARGARGCNGAYAARYTNATHAAYCAR TCNCCNGAYGARGAYATHTAYMGNGARTCNGCNGCNCCNGTNTTYGAYGAYYTNGCNAAR ATGMGNGARATGATGATHYTNAARAARCCNACNGGNTCNACNYTNAARYTNGCNTGYAAR GCNTCNGGNAAYCCNYTNCCNGARGTNCARTGGTAYAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ACNTAYAAYACNCAYAARCARGTN GARMGNTTYGTNAAYGARCARATHGAYCAYYTNCARTGYACNTGYAARGCNYTNAAY--- AARGAYGAYCAYGAYCAYGCNGGNYTNGAYACNGTNACNTTYGCNGCNATHGGNGTNGGN GCNGTNYTNYTNATHATHATHYTNGGNYTNGCNTAYTTYTGY------CAYMGNMGNAAY CARMGNAARMGNAARAARMGNGGNCCNAGYGTNATHTAYYTNCCNGCNGCNAAYTCNGAY AAYTGYCCNGTNTAYCARGARATHTTYGAYCARMGNTCNCCN------------------ CCNCCNACNYTNCCNGGNMGNTAYAGYTCNMGNCCN---------------YTNCCNGGN CAYCCNGAYGAYACNGARTAYYTNGARCCNGTNCARGCN---------TCNAGYAGYTAY MGNGCNAARGCNCCNCCNCCNYTNCARGTNAAYAAYCCNGGNTAYTCNGCNGAYGCN--- ---CCNCCNGARTAYACNGARACNGAYCARACNTAYGAR------------GAYGCNACN TTYATHGAYCCNTCNGARGTNAAY---GCNTAYTTYGARCCNGTNGTNACNCCNAARTCN GARAARACNGARGARGARATHGARGARGGNGCNGGNGGNGGNTAYGAYAARYTNGAY--- ------------------------------------------------------------ ------------------------------ATGYTNGARGARGGNACNGTNACNATGGAR AARAARTCNATHACNMGNCARTCNCCNGGNTCNGGNCARTGYAARAAY---GGNGCNCAR ACNGARMGNAARTCNGAYTTYACNAARMGNGCNAAYGGNMGNMGN---------TCNGGN TCNAGYGGNGGNGCNAARACNCARGAYGTNGCNCAR---CCNCCNMGNCCNAGYCCNCAR AARTGGGAYMGNTCNGTNGGNAAYMGNMGNCARMGNCARMGNAGYGGNTAYGAYTAYMGN CARMGNGARGARGTNGARGARCAYGAYGAYGTNTTYGAYGTNYTNAGYACNGGNTCNMGN AARGGNAAYYTNAAYCAYYTNYTNAAYTTYAARTTYYTNCCNMGNMGNCCNAGYCARAAY GGNGGNTAYMGNTGGAARGGNCAYTAYAAYTAYCARGGNMGNGGNGGN------TAYCAY AARMGNAARMGNTAYAARAARGARCARTTYYTNCARGCNAGYTGYCARTTYGTNGTNMGN GAYACNGGNGAYTAYACNGARCARGCNATHAAYTCNGAYGCNYTNGTNGAYTGGAAYATG ATHGARYTNGTNMGNAGYTTYAGYTCNGARGCNGTNAAYTGYCCNATHTGYYTNGARACN CCNATHGCNGGNAARATHACNAARTGYGGNCAYACNTAYTGYTGGGCNTGYATHYTNCAY TAYYTNAARYTNGGNCARGGNGARGCNMGNAARTGYCCNATHTGYTAYGARAAYGTNGAR GTNGARGAYYTNAARAGYGTNCARTGGATGGAYGTNCCNAAYTTYAARGTNGGNGAYACN ATHGAYATGATHYTNATGAARAARGCNAARGGNAGYGTNATHGCNATGCCNAARGAYCAR TGGGARGAYMGNYTNGGNAARCCNATGAAYATHCARGAYATHGCNAAYACNGARTAYATG AARYTNYTNGTNGCNTCNTCNGAYCARATHCARGCNGARGTNATHGARMGNGARMGNACN GCNYTNACNGTNCARYTNGAYGAYGCNGARGARTCNGARGCNTGYTTYATHCARATGGCN YTNAGYTAYYTNGARACNMGNGARAARTCNYTNAARCARGTN------------------ ------TTYTGGCARACNGCNCARAAYAARGAYAARGCNCAYATHCCNGGNYTNTGGTCN GAYAGYGAYACN------------------------------------------------ ------------------------------------------AAYCCNCCNCARGAYACN ------------------------TTYGAYAAYGAYGARATHCCNGAYTCNAARTGYYTN ACNACNGARACNTCNGARATHGCNYTN--------------------------------- ---AARGAYGARACNATGAAYGCNAGYGCNCCN--------------------------- YTNGAYTCNGGNGAYTCNMGNCARMGNCAYGAYAGYGARTGYTCNYTNCCNTTYGGNTCN CCNCCNAGYCCNTTYCCNYTNGTNGTNGAYCARGARGTNAAYCCNGTNCCNYTNAGYYTN GARGAYATGGGNGAYCAYYTNGARYTNCCN------------ATHAAYATHCCNCARACN GCNACNAARCARCARTCNMGNATGAARGAYAAYTAYTAYTTYTAYCARGCNTCNACNGGN CARCARATHTAYYTNAAYTCNYTNAAYGCNCARTGYATGGCNMGNGARTAYGGNTCNYTN GARGARAGYCCNGCNAAYYTNCARGGNAGYATHGTNGCNATHGARMGNATHTTYATGACN GARGAYGTNMGNAARMGNYTNMGNTAYYTNGAYCAYATHCCNYTNACNTGYGARGTNCAY ATHGTNGARYTNAARYTNAARCCNCCNGTNGTNAGYAARGAYACNYTNAARTTYTTYGAR GCNGCNTTYGARMGNAARMGNAARCARMGNCARCARAARGAYMGNGARGAYAARMGNMGN GCNAARCARATHGARATHGAYCAYAARAARMGNYTNGGNYTNTAYCCNGARGTNTTYYTN CCNYTNGAYAGYYTNGARCARTTYCCNTCNCAYYTNGCNGCNAGYATGGAYGCNYTNGGN CCNATHMGNGTNTGGYTNAARMGNTCNTAYAAYATHGAYGTNGCNGAYGAYTGGYTNTCN ACNTGYATHGARTTYATHMGNCARGARACNCARAGYTCNMGNCCNACNYTNGARGARYTN AARMGNYTNGTNTTYGARCARTGGYTNGGNTCNGAYYTNTCNGARATHGGNAARCCNTCN YTNCCNGAYGARGTNTTYGTNCAYGARAARTGYTAYYTNGARCAYGTNTAYCCNYTNCAR ATGATHTCNATHATHGAYGTNTCNACNCCNYTNTTYGGNCARYTNCARAARTTYCARTCN ACNGGNTCNCCNGAYYTNATHACNTTY---TCNGAYAAYCCNTTYGARACNCARACNCAR CAYGCNTTYGGNAAYTCNGCNMGNTCNTCNMGNATGYTNAARYTNGARYTNACNGAYGGN GARMGNACNGTNCARGCNATHGARTAYMGNCCNATHMGNTCNYTNCAYCCNGAYYTNCCN GCNGGNACNAARATHGTNATHAARGGNGCNGTNYTNTGYMGNMGNCARATGYTNYTNYTN GARGARCAYAAYGTNTGYGTNYTNGGNGGNGARGTNGAYGAYYTNATHGTNGTNAGYAAY CCNYTNATGAAYYTNCARACNGARYTNGAYMGNAAYMGN---------GAYAAYGAYAAR GAYTTYATHGGNGAYGARYTNTTYCARGARGGNCCNAAYGARAAYGAYCARTAYTCNMGN CARYTNGGNGAYGARGTNGARGAR---------------ACNAARCCNCCNACNGCNCCN ACNAAYATGGTNYTNTTYTAYACNTGGATGATHYTNGCNATHYTNGTNATGGTNATHGCN GTNTCNACNTAYCARGCNAARTGYAARGGNATHYTNTCNAARGGNGGNMGNCARCARACN MGNGGNGARGAYMGNAARMGNYTNYTNGAYAAYGARTTYGTNATHACNYTNYTNGAYATH CCNTGGGARCARGTNYTNTGYGGNAAYATHYTNCCNTAYYTNAGYATHCCNGARYTNTTY MGNYTNMGNTCNGTNAGYCAYAGYTGYYTNTGYYTNGTNGAYACNTAYTTYAGYYTNCAR YTNCAYYTNAGYATHTGYCAYYTNGGNAARAARYTNACNTCNGARGCNTTYTCNYTNATG ACNMGNGARAGYMGNTGYYTNAARACNYTNTTYYTNMGNGGNGCNAARTAYGGNYTNAAY AAYGARGTNTTYYTNCCNGTNYTNGCNAAYAAYGCNMGNYTNGARAARATHGAYATHAGY GGNTGYACNTCNYTNTCNGGNTGYGTNYTNTAYGCNATHGGNGTNAAYTGYMGNAARYTN AARCARYTNATHGCNMGNGAYTGYGTNACNTTYATGGARGARAAYTTYYTNTCNTTYYTN TGYGTNAARCARCCNGTNCAYYTNGARTAYYTNGAYATHTCNGGNTGYTGGAAYYTNGGN GAYGAYYTNYTNATHAARYTNGTNCARMGNTGYCCNAAYATHAARCAYYTNYTNYTNGGN AAYYTNTAYGGNYTNACNGAYMGNACNGTNTGYGCNATHGCNCAYTCNTGYCCNGGNYTN GTNTCNYTNAGYATHGTNGGNTGYTGGMGNATHACNGAYCAYTCNATHAGYYTNGTNGCN GCNTAYTGYCCNAGYYTNCARYTNYTNGARGTNAARGARTGYMGNGAYATHACNGARGAR AGYYTNGGNCCNYTNMGNAARMGNCARGTNAARATHGAYAARCCNGGNCCNCCNCCNTCN TAYYTNAAYMGNYTNGARTTYYTN------GCNCAYAARATHAAYGTNATGYTNGAYAAR GTNATHYTNTAYAGYTAYTTYMGNAGYTCNTGYAGYTGGMGNGTNMGNATHGCNYTNGCN YTNAARAAYATHGCNTAYGAYTAYGARGCNGTNCAYYTNGTNAARGGNCARCARMGNACN GAYGARTAYAARAARYTNAAYAGYTCNGGNTAYYTNCCNACNYTNAARATHGAYGGNYTN ACNYTNACNCARTCNYTNCCNATHYTNGARTAYYTNGARGARMGNAGYCCNGARCCNGCN YTNYTNCCNAARGAYAARGCNGAYMGNGCNCARGTNMGNGCNATHGCNGARATHATHAAY AGYGGNATHCARCCNYTNCARAAYYTNAARGTNYTNCARAARGTNGGNGAYACNAARATG GARTGGGCNAAYTAYTTYGTNACNGCNGGNATGGARGCNYTNGARCCNGTNYTNGARAAR ACNGCNGGNACNTAYTGYTTYGGNGAYMGNGTNACNATHGCNGAYATHTGYYTNGTNCCN CARGTNGCNAGYGCN---GCNMGNTTYAAYGTNGAYATGTCNMGNTTYCCNACNATHTGY MGNGTNAAYAARGCNYTNGARGARYTNCCNGCNTTYAARGTNGCNGAYGCNMGNMGNCAR CCNGAYACNCCNGARGAYATGMGNATHGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GCNTAYAARAGYTAYYTNATGCCNYTNAAYTAYYTNGARGGNATHCAYACNGAYTGY AAYYTNACNGTNTCNTAYATGAARTTYGARGGNGARAARGAYTTYYTNCAYYTNAARAAR MGNYTNGARAGYTTYCCNTCNMGNGTNGCNCARGTNATHGCNATGTGYAARAARGGNGTN GAYMGNGGNATHGTNAAYTCNAARCAYTCNGTNCARGAYATHCCNGGNCARYTNGAYATH ATHYTNGGNACNCCNGTNGAYGAYTGGGGNYTNATGGARCCNTTYAARGARAAYAARTCN GGNYTNGAYCCNGCNYTNTTYGCNACNYTNAARACNCARTGYMGNGAYATHGTNYTNTCN GCNATHATGCCNGCNTTYCARGAYYTNAARACNTAYATHGTNGARGAYTAYATGACNAAR ACNMGNCCNAARGARGGNGTNAAYAGYYTNCCNGAYGGNGARGAYTGGTAYCARCARTGY YTNAAYTTYCAYGTNACNTGYCCNYTNACNCCNCARGARGTNCAYGAYATHGGNYTNMGN GARGTNGCNMGNATHACNGCNYTNATHGARGCNACNGCNMGNAARGARGGNYTNCCNGAR ACNATGCCNGARYTN---YTNGARGCNATHGARMGNAARGCNAAYTCNTTYCARTTYCAR GARGARGTNYTNAARTAYGTNGARGAYYTNTGYTAYAARAARATHMGNCCNAARATHGGN GAYTAYTTYAARGGNYTNCCNGAYATHAARATGAARATHCARYTNACNCCNGCNTAYCAR GCNTCNGCNCCNGCNGGNTAYTAYYTNAAYGGNACNCCNGAYGGNTCNMGNGAYGGNGCN TAYTTYATHAAYGCNAAYAAYYTNGAYGCNTGYYTNCCNTAYTCNYTNCCNGCNYTNTGY YTNCAYGARGGNGARCCNGGNCAYCAYYTNCARGGNATHTAYTCNYTNGGNTCNACNCAY YTNCCNGAYTTYMGNMGNTAYTCNGARGAYAGYAARTAYTAYYTNTCNCCNTGYAARTTY TCNTTYAAYACNGGNTAYACNGARGGNTGGGGNYTNTAYTGYGARGCNYTNGGNGARGAR ATGGGNYTNTAYACNAAYAAYATGGARYTNYTNGGNMGNTAYAAYATGGARATHTTYMGN GCNGCNMGNYTNGTNGTNGAYACNGGNYTNCAYGCNTTYGGNTGGAGYAARGARAARGCN GTNGARTAYATGAAYAARCAYATGCAYGCNCCNGGNTTYCARYTNGCNCAYTGYYTNCCN CCNGCNGGNGTNGGNMGNCCNAARGAYYTNGAYATHTAYMGNTTYCAYMGNGTNGTNCCN YTNTAYACNCCNGAYCCNTGYATHGGNCCNAGYCARGGNCARYTNATHTGYCCNCCNGAY TGYGGNTAYCARAARMGNAAYGAYYTNATGCCNCCNGCNGGNGTNCCNMGNCCNGAYAGY GAYTCNTTYCARTTYTAYGAYACNMGNMGNGAYGCNCCNAARCCNAARCCNGCNTGYGCN TGYCCNGCNTTYGCNAAYAAYCARCCNTGYGCNTCNYTNGGNTCNATHACNGAYCCNYTN AAYTGYCCNTGYATHAAYATGTCNGAYAARYTNACNACNMGNGTNATHCARGTNACNAAY ATHGCNCCNAGYTGYTCNAARGARCARYTNMGNACNYTNTTYGGNTAYYTNGGNMGNATH AARGARYTNGARATGTTYCCNCCNGARGGNGCNGAR---GGNGTNGTNACNGCNMGNGTN GCNTAYATHGARTTYGARGAYTCNGTNACNACNGGNGTNGCNYTNCAYYTNAGYAGYACN GTNTTYATHGAYMGNGCNATHATGATHGTNCCNGTNATGGAYGGNAARATHCCNGAYGAR AGYTCNGCNYTNCARYTNACNCCNTCNGCNGTNGCNGGNATGYTNCCNGGNCARCCNACN TGGCCNGCNAAYGTNGTNTCNCARGTNACNGGNYTNGGNGCNAAYCARATHATHATGACN AAYGAYCCNMGNYTNACNTCNYTNGGNYTNCCNCARTAYCCNCCNYTNCCNGCNACNACN GAYCCNAGYAARATHGARGARATHMGNMGNACNGTNTTYATHTCNGAYYTNGAYTCNAAR GTNACNCCNGARTCNYTNYTNTCNTTYTTYTCNCARACNGGNGARATHAARTAYGTNMGN ATGGCNGGNGAYGARAAYGCNCCNACNMGNAGYGCNTAYATHGARTTYACNGAYCARMGN TGYATHGCNCARGCNYTNAGYTAYAAYAAYGTNGTNTTYCARGGNMGNACNGTNAGYGTN AARCAYGCNACNACNAGYATHGTNAARCCNACNCCNMGNTCNGARGCNTCNCARMGNGAR ATHGAYGAYGCNATGAARAARGTNAARGARGCNTCNAARYTNATHTCNGCNGCNGCNAAY AGYGAYMGNGARGGNTCNMGNTCNCCNACNMGNAARMGNTCNMGNTCNAARGGNMGNAGY MGNACNMGNTCNAARTCNMGN---MGNMGNTCNMGNACNMGNTCN---CCNMGNMGNMGN MGNMGNAGYAAYTCNMGNCCNMGNMGNMGNTCNMGNTCNMGNMGNMGNTCNCCNAARMGN TCNMGNAGYCCNGTNGTNMGNMGN------------------------------------ ---------MGNMGNTCNMGNTCNMGNTCNMGNMGNMGNTCNMGNACNMGNTCNCCNGTN MGNMGNMGNMGNTCNMGNTCNMGNTCNAARTCNMGNCCNMGNMGNTCNMGNACNCCNCCN AARTCNTAYAGYMGNGGNMGNMGNTCNMGNTCNMGNAGYMGNMGNAGYMGNTCNMGNGAR MGNMGNGARAARMGNGARMGNAARAARAGYAGYTCNATHTCNCCNCCNACNYTNATHMGN GARGTNTCNGCNTCNMGNGARGAYGCNAARGAYAARTCNCCNGTNAARGGNAAYGGNMGN TCNCCNAGYCCNCCNAARGCNAARAARMGNAGYCCNACNCCNAARMGNMGNAGYMGNTCN MGNTCNCCNAGYMGNMGN---AARAARMGNMGNCAYTCNMGNTCNACNTCN---MGNAAR MGNTCNMGNTCNMGNAGYGGNTCNMGNCAYMGNTCNMGNMGNGARAARAARMGNAGYMGN AGYMGNGAYMGNAARCAYGAY---AGYAARAARAARAGYAGYMGNGAYAARGAYGAYMGN AARAARGAR------AGYAGYTCNAARATHAARMGNGAYTAYGAYGARGARGARAARGGN TTYGCNAGYGAYAARAGYGARGARMGNGGNGAYAAYGGNAGYGAYGARGCNGGNTCNMGN GCNGARTCNCCNAGYCARCCNCCNATGYTNGARAARGAYACNGAYAAYCARCCNGTNGAY ATGGAYATGAGYGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GAYGCNTAY GAYMGNTTYMGNAGYACNGTNGAYAAYTCNATGGGNCAYGARYTNAGYTGGAAYACNYTN GCNYTNYTNTTYTAYGCNACNAARGGNGTNGTNTCNGCNGTNGGNAARAGYTCNCARGTN GCNACNCARGCNAARGARTTYACNYTNAARTAYATHAGYGAYACNTTYGTNTCNTGGATH ATGGARCARGGNGGNTTYGAYAGYATGYTNAGYGGNAGYGARTCNGAYCCNGARYTNGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR TTYGTNGCNGTNGARAAYAARMGNYTNAGYAARCCNGAYGCNGCNCCNACNCCNATGTAY GARATHATGATGMGNTGYTGGGCNCARAAYCAYGARGAYMGNCCNAAYTTYACNGCNGTN AARMGNCARYTNGARATHYTNAGYGGNAARGGNGAYTAYATHCCN--------------- ------------------------------------CAYYTNTGYATGATHAGYCCNCCN CARMGNGGNTCNATGATGGGNATHAAYAARCCNGGNGCNTCNGAYTGYATHYTNYTNAAR TCNCCNTGYGGNGGNMGNGGNAARGGNAGYACNATHYTNGARYTNATGGCNGGNTCNAGY TTYACNGTNACNYTNATGAARAAYYTNGAYCAYTTYAAYAARGCNGCNCCNGGNAARTTY ACNGTNAAYATHGGNAARGARGGNGGNTCNTTYACNCARYTNYTNTCNTTYCCNGAYAAY GCNGAYCCNGCNYTNACNYTNTAYTCNTAYAAYGTNACNATGCCNAAYGTNCAYGGNGAR ATGGTNYTNCARTCNGTNTAYACNACNAAYAAYGCNCARGCNCCNCCNGCNTTYTAYCAR TGYAGYGAYGTNMGNATHGTNCCNMGNCAYMGNTAYCCNMGNTTYYTNCARCCNCARATH TTYYTNTCNGCNYTNGTNGTNYTNYTNATGMGNTAYGAYATGCCNGARATHAGYATHGAY TTYYTNMGNAARTAYGGNCAYGTNGAYCAYAARATHGARYTNGTNACNGAYGARGCNATH GCNGCNATGAAYGARACNGARYTNATGGTNACNGTNCAYAGYTTYYTNGAYAAYGCNGAY ATHYTNTGYMGNMGNAARATHMGNATGGGNCAYATGGGNGAYGGNGGNTGGGARATHTGY GAYGAYCARGGNYTNMGNCCNMGNGCNCCNCCNTGYYTNGTNTAYTCNTTYGGNGTNATH TCNGAYTAYGCNTTYGARGAYGAYGTNTCNMGNATHTAYAARTGYAARGTNCAYTCNTTY AAYCCNAAYYTNCCNGGNACNGAYTTYAAYMGNTCNCARTCNGTNYTNATHCAYCCNTAY GGNGCNGGNMGNAAYACNGARATHACNCCNAAYGGNAARGARYTNTAYACNYTNCARGAY ATHMGNTCNATHYTNGGNCAYGCNGAYACNGAYATHGAYGTNATHAARATHGAYACNGAR AGYACNGARTGGGCNATHYTNACNCAYATGACNACNAAYGGNCARYTNGAYAAYGTNAAR CARYTNYTNGTNGARTTYCAYATHGGNTTYCCNCCNAAYGTNTAYAARYTNAGYMGNGCN ATHAARATHYTNMGNGGNYTNAGYMGNYTNGGNTTYMGNAARTTYTAYGTNCAYAARAAY CCNAARGGNTCNTTYCAYCAYCCNGGNTTYCCNGTNGTNMGNGCNAARAAYTAYGARGTN CAYTAYATHAAYGCNAAYTTYYTNTCNAGYYTNAAYTAYGGNTCNAGYAAYCCNGTNAAR ACNMGNGCNGGNCARGTNCCNTGGGTNMGNYTNAARMGNMGNGARTCNYTNGGNYTNGCN GAYTAYATHAGYAGYMGNGCNCCNCARAGYCCNAAYACNGTNAARATHGCNCCNCCNATG ---AAYYTNYTNCCNGCNGCNCCNAGYTTYMGNAGYAGYCCNYTNATHGTNACNACNGAR GCNAAYMGNTCNMGNATGYTNGAYACNCARAAYGTNGTNTCNGCNYTNMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARATHTCNCAY ATGATHGCNTTYATHGAYCARGARGCNTCNGARAARGTNGARGARATHGAYYTNAARGCN GARGARGARTTYAAYATHGARAARGGNMGNYTNGTNCARCARTCNMGNGTNCARATHATH GAYTAYTAYGAYAARAARGTNAARAAYGTNGARYTNCARAARAARATHCARAGYTCNAAY ATGCARAAYAAYGCNMGNYTNGARGTNYTNMGNAARAARGARGARTAYGTNAARGARGTN YTNGAYGARGCNMGNGARCARYTNAARMGNGTNGCNATGGARAAYCCNGARGARTAYAAR CAYYTNYTNYTNMGNYTNATHATGCARGCNYTNGCNMGNYTNGTNGARTCNAARGTNACN ATHMGNTGYMGNMGNGARGAYGTNCARATGATHAARAAYGCNGTNCCNGGNYTNGTNAAR GARTAYAARGARYTNYTNAARGGNAARTAYCCNYTNGARYTNGTNGTNGAYGARGAYAAR TTYYTNCCNCARGAYATHTGYGGNGGNGTNGARYTNCAYGCNATGAAYGGNAARATHGTN GTNGTNAAYACNYTNGAYGARMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MGNTTYTTYGCNGTNAARCCNTCNMGNGAYATG YTNGAYTCNAGYAAYATHTTYACNCAYGAYAARATHYTNCARYTNGTNAARAAYACNACN GAYAAYAGYMGNYTNCAYGTNATHTTYAAYAAYAARAARAARTAYACNTAYCARTTYGAR TCNGCNYTNYTNMGNGARAGYTTYTGYYTNCARATHMGNCARATGAARTCNYTNCAYTCN GARGARCAYGAYATHGAYAAYATHTCNATHTTYATHGGNACNTGGAAYATGGGNAARTCN GCNCCNGTNGARAGYYTNAARTAYCCNGTNGTNTTYATHCARMGNGTNGARTCNTTYAGY GCNTGYCAYMGNYTNCAYAGYCCNTAYYTNAAYGAYGARAARAAYGCNGCNATHTTYGGN AARTGYAAYCAYCCNAAYGGNCAYGGNCAYAAYTAYACNGTNGAR--------------- ------------------------------------------------------------ ATGGCNGARGGNGAYCARCARTAYACNATHTAYGAYGCN---AAYCARCCNYTNACNYTN ACNGTNGGNAAYGTNAAYCARGGNACNGARGAYGCNCARGCNGTNCARAGYATHCARTAY ATHTCNTCNGAYGGNGTNCCNGTNACNCARYTNGAYTCNAAYGAYGTNATHCARGTNGCN CARGCNGCNGAYGGNACNTTYCARCARGCNACNGCNGGNTTYCARAAYYTNCARACNTCN GTNCARCCNCARYTNGTNGCNAAYACNGCNTCNGTNCCN---ATGGTNTCNACNTCNCAR GGNGGNTCNATHYTNCARTCNGGNAAYGTNYTNMGNAAYGTNGCNCARCARCARCAYACN TCNCARCARCARCARCARGCNYTNCARACNGCNGGNACNTCNACNCCNACNGTNGGNACN AAYGCNGCNGGNATHCCNCARATGYTNTTYYTNAAYCARGTNACNATHAAYGGNCARACN TCNTTYGTNYTNGTNGAYGCNAAYAAYAARCCNATHCARYTNCCNCARGGNATHCARGTN ATHAAYYTNCCNCAYCARCARYTNCCNGGNCARTCNATHCARATGCCNGGNAGYGAYACN GGNGAYGARCCNYTNTAYGTNAAYGCNAARCARTAYCAYMGNATHYTNAARMGNMGNCAR GCNMGNGCNAARYTNGARTCNGARGGNAARATHCCNAARGARMGNCARAARTAYYTNTAY GARTCNMGNCAYMGNCAYGCNYTNAAYMGNGCNMGNGGNTCNGGNGGNATHTTYGTNGGN CARACNGCNTCNGTNGAYGTNATHYTNGTNGTNGGNAARAAYAARATHCCNGTNACNGTN AGYGCNCAYCARCARGARGGNAAYGAYGAYAGYYTNACNGTNMGNCAYYTNTGYGARACN ATHCARCARCAYACNAARATHGCNCCNCCNGCNCARAARATHATHTTYMGNGGNMGNACN YTNTTYAARACNTTYAARCCNGARGAYCCNAGYYTNAARAARAGYYTNTCNTCNYTNGGN ATHAARAAYGGNGAYMGNATHATGGTNTTYGGNAARCCNTCNGTNGAYGARAARGARGTN GARGGNAAYGAYCCNAARYTNGAYGARATG------AARGTNYTNGAYAGYCAYCARACN AARATHGARGARATHTGYYTNYTNTGYMGNGAYATGGTNGARAARATHMGNGAYAAYCCN GGNACNYTNGARGARTGGAARAARCARMGNAARTTYTTYYTNTGYCARTCNGARTAYTCN ATGCARGARYTNACNMGNYTNGAYGCNACNCCNGTN------TCNCAYCAYGGNGAYTAY AARGCNMGNMGNAARGCNYTNGTNAAYMGNYTNYTNGARAAYGTNACNATGTGYGAYAAY CAYGTNTCNMGNYTNGAYGTNTCNATHMGNGARGCNGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARGTNTAYGCNATGATGGARGARAAYAAY ATHCCNCAYCCNMGNTAYGCNGTNYTNGAYMGNGARAAYGAYCCNGAYTGYGARGTNATH GARACNGARGAYTCNATHGARTTYAAYGGNAAYATHTTYATGAARCCNTTYGTNGARAAR CCNGTNGAYGCNGARGAYCAYAAYATHTAYATHTAYTTYCCNCARGCNGCNGGNGGNGGN AGYACNMGNYTNTTYMGNAARATHAARGAYMGNAGYAGYGTNTAYYTNMGNTTYTGYMGN GTNMGNAARAARGGNTCNTAYYTNTAYGARGAYTTYATGCCNACNGAYGGNACNGAYGTN AARGTNTAYACNGTNGGNCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TCNTCNTCNTCNTCNTCNTCNTCNTCNAGYGAYTCNTCNGAYGAYGARTGGAARCAYYTN CCNAARCAYGARAARAARATGMGNAARAARTGGAARAARGAYATGMGNAARGGNCAYATH GCNMGNGGNACNYTNCCNCCNTGGCARGGNGGNGCNGCNTGGGCNCCNCCNATG------ ------------AARCAYGGNAARAARGGNCAYAARGGNGCNGCNGGNTAYCCNATGGGN GCNGTN------------------CCNCCNCCNCAYGCNGGNTAYCCN------------ ------GGNCARCCNGGNTAYCCNGCNCARCCNGGNTAYCCNGCNCAYGGNCCNGGNGCN TAYCCNGCNCCNCARAAYCCNTCNTAYCCNCCNCCNCCNGGNGGNCARTAYCCNGGNGGN CCNGTN---CCNGGNGGNTAYCCNGCN------GCNCCNGGNGGNCAYTAYCCN------ ---CCNCCNCCNCARGCNCARTAYGCNCCNCCNCCNGGNGCNGCNTAYGGNGCNCAYGGN GCNCCNTCNGGNCCNTTYCARGTNCCNCCNGGNGGNGCNTAY------CCNCARCAYGGN TAYCCNCCNCAY------------------------------------------------ ------------------------------------------------------------ GAYAARMGNAAYATHYTNATGGARYTNGARTCNGCNACNGCNGARMGNACNTCNYTNAAY GCNGARAARGCNTCNYTNTCNCARMGNGCNGARGTNYTNCARGCNCARYTNCARGAYATH GARGAYAARACNMGNGCNATHCAYGARGARAARTCNAAYGCNGARATHAARYTNMGNGAY AAYYTNGARMGNYTNGAYCARYTNGARTTYGARAARACNATGATHTCNGARCAYGCNTCN GARYTNCARGGNACNATHCARGAYYTNGTNTCNCARAARGARATGACNGARAARGARYTN AARGARGARATHMGNGCNMGNATHTCNGCNGARGARMGNYTNAARGAYGCNGARAARTCN YTNAAYTCNYTNGAYCAYGCNGTNCARGCNCARTCNCAYMGNATHGARGAYACNGCNAAR GARGAR------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GTNTTYGCN GGNGTNTTYYTNGGNAGYATGTTYTGGGGNTGGYTNGCNGAYAARAARGGNMGNAARTTY GTNYTNYTNYTNTCNYTNGTNTTYACNAGYYTNAGYATHACNGCNTTYAGYYTNTCNAGY ACNATHCCNATGGCNYTNACNATGMGNTTYYTNGCNGGNYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR YTNATHTAYTTYGAYYTNAARGGNMGNGGNCARYTNTCNMGNATGYTNTTYGCNGTNGGN GGNGTNGARTTYGARGAYTAYMGNATHAARTTYCCNGAYTGGCCNCARATGAARGARTCN TTYCCNTTYAARCARATHCCNGTNYTNGARGTNGAYGGNGTNCARTTYGCNCARAGYTTY GCNATHGCNAAYTAYYTNGCNAAYGARTTYGGNYTNTAYGGNAARAAYAAYATHGARMGN YTNAARATHGAYCARATHYTNGARYTNATHAARGAYTAYYTNTTYTAYGCNAAYAARTCN TTYAARGARTCNGAYAARGAYAARAARGTNGARTAYATGAARGARGCNATHGARGTNCAY AGYGTNACNTAYYTNAARTAYTTYGARGAYATGYTNACNAARAGYGARACNGGNYTNTTY ATHAGYTCNGARATGACNYTNGCNGAYYTNGCNGTNTAYGAYATHYTNGAYTAYATHACN GARMGNMGNCCNAAYGCNYTNGAYGAYTTYCCNCAYYTNAARGCNTTYCARGARMGNATH AGYGCNAAYGARAARATHAARAARTAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GGNTAYGGNCCNTCNTAYATGACN CCNMGNGCNGCNACNYTNCCNYTNGCNGGNGCNTAYGGNGCNMGNGAYGAYTGGMGNTTY TTYGARTTYGAYGARTCNGAYGAYMGNCCNAAYACNAAYYTNTCNTCNTCNACNYTNACN GGNGAYACNAGYTCNMGNMGNCAYGAYTCNTCNTTYACNGGNTAYGAYGGNCCNAAYATH TCNYTNYTNAARYTNCARAARAGYACNTGGCAYGCNGARATHGARCCNCCNATHTAYGAY TAYGARMGNYTNAARATHACNAAYTTYGAYYTNCCNAARGAYGTNGAYAGYAAYCAYYTN GARATHCAYYTNACNAAYGARGAYTTYGARGARYTNTTYAARATGCCNMGNGARAARTTY TAYMGNATGGCNGARTGGAARMGNAAYGAYGTNAARMGNAARYTNAAYYTNTAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AAYTCNAAYATHMGNCCNTTYAGYGAYTTYGARTGGCARCCNYTNGAYGTNACNCAY ATGAAYGAYAAYTTYATGTTYAAYACNACNGAYGAYAARATGGAYAARTCNGARTCNAAY AAYGGNAGYYTNTCNTTYTCNTTYMGNGTNCCNTCNGARGAYGGNMGNGTNTCNGCNYTN CCNTCNCARMGNTAYYTNGCNAAYGARACNGTNTTYGARTTYYTNYTNGAYAARTTYACN CCNTCNYTNAAYAARTCNMGNTTYGCNYTNGARACNGTNGCNGTNAGYCARTCNAGYAAR AAR---ATGGAYGTNAARACNATHAARACNATHGAYGAYGARTAYTCNCCNGGNGTNTTY YTNYTNACNAAYTGGYTNACNAAYCCNTCNGAYAAYTCNAARTCNGGNTTYGTNCARTGG AARCCNGTNTCNTAYTTYGGNTCNGAYMGNGGNMGNAARACNGTNACNAARGTNAARAAY TAYAARYTNAARGARGTNGAYCAYGTNGAYGARYTNAAYGCNACNYTNYTNTCNGCNYTN TTYGGNGAYCARYTNTTYGAYAAYAARTTYGAYGTNAARAARATG---AAYATHTCNTTY GGNCARCCNAARGAYGGNTAYTAYYTNAARAAYAAYTAYACNGTNTGGGAYGGNGCNATH GGNTAYGGNAAYCCNCCNCARGAYGARATHTCNYTNACNGTNATHATHATHATHTCNACN GGNYTNGGNATHCCNGTNYTNYTNTGYATHGTNGGNGGNGTNTAYACNATHTCNMGNGCN GTNMGNAAR---MGNMGNTCNCARTAYGARGCNATHAAYGGNGGNAGYCCNGTNAAYCAR GAYMGNCCNCAR------ATHAARGTNYTNGARTTYGTNYTNGCNATHTTYGCNTTYGCN ACNACNACNAGYCCNGAYACNTCNACNACNTTYACNGTN---AAR---GAYTGYTTYAAR TGGAAYAAYGTNACNGGNCCNGCNTCNAARACNTTYTCNTAYAGYTAYCCNTAYGAYYTN GARAAYGTNTGYTTYCARYTNCCNATHTGYCCNGGNAAY---ACNGCNGTNCCNAARAGY GARTTYTGYYTNYTNGARGGNTCNCARTCNTCNGCNCARTTYTAYGTNTTYGTNGGNGTN ATHGTNTTYYTNTAYTGYYTNGGNGCNYTNGTNYTNTAYGTNTTYTTYGAYGARATGTAY MGNMGNAAYTCNMGNATHGTNYTNGCNGAYTTYATHGTNTCNTGYGTNYTNACNYTNTTY TGGATHATHTCNTCNTCNGCNTGGGCNGCNGGNYTNGAYGAYGTNAARYTNTAYACNGAY CCNTAYGAYGGNGGNATHTTY---CARACNGTNGCNGARTGY---CARACNAARGGNGAY TGYYTNACNGCNAAYGARGGNAAYTTYGCNAGYYTNAAYGTNTCNATHATHTTYGGNTTY YTNAAYTTYGTNGTNTGGYTNGGNAAYYTNTGGTTYYTNTAYAARGARACNCCNTGGTTY AARGTNCARGCNMGNCCNCCNACNCARCCNYTNTCNAARGCNGARYTNGARTGYGARTGG MGNYTNGCNTCNTGYYTNYTNAAYGARAAYGARCAYATHMGNGARAARYTNAARGGNAGY GARGGNYTNTCNTCNTTYTTYAARTCNTTYATHCARATHGCNGARAARTGYYTNAARGTN AAYGGNATHCCNGARMGNCCNTGGAARGAYCAYAAYCARAGYATHYTNAAYCARATHCAR AARATHGGNTGGAAYAARGTNTTYAAYYTNGCNGAYAAYTTYTCNAGYGTNGARTTYGTN TGYCAYGAYAARAGYCAYMGNCAYCAYAARYTNMGNGTNAAYYTNAAYAARGARGAYTTY CARGCNMGNCCNAARTGYATHACNGARYTNCCNCARGARTTYGAYTTYCAYTGGTCNTCN ACNGCNCARYTNAAYGAYYTNGTNYTNCARTTYGARAGYTGYYTNAAYCAYTAYCARGAR TTYTGGGAYATGGTNGARGARATHGAYAARAARACNTGGGTNYTNGARCCNGARCARCCN ATGYTNTCNTGYACNTAYMGNMGNATHGCNYTNGGNCARAAYYTNTCNYTNCAYATHATH ATHAAYCCNYTNCARCCNTCNAGYYTNCCNGARTGYMGNATHYTNGGNTCNGARTCNACN GTNGCNCCNYTNMGNGARAARYTNAAYGTNAAYYTNCAYYTNTGGGAYYTNGAYMGNTCN YTNYTNAAYAAYYTNCARGARGTNYTNGARATHGAYTTYCCNACNCCNTCNGARTCNACN AARGARGARYTNAGYGTNGAYTGYGGNATHTGYTAYAGYCAYCAYYTNGARGARGARATH CCNGAYATGGTNTGYCARCAYCCNCCNTGYAGYCARGCNTTYCAYTAYACNTGYYTNTAY GARTGGYTNMGNAAYTCNTCNTGYMGNCARAGYTTYAAYTAYATHTTYGGNGARTGYCCN TTYTGYAGYAARCCNATHMGNATHAARYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CARCARCARCARCARCARCARCARTGGTGGCCNGGNAAYAAYCAR---ATGTGGATG CARCARCARCARCAR---------------------GGNGAYATGTCNACNATHAGYTTY GGNAAYGCNGGNCAYCARGAYGGNATGYTNAARGGNGARGCNTTYAAYCARTAYTGGGAR GARCCNGARAGYAAYGAYGARGGNMGNMGNCAYCCN---------CAYCAYCAYMGNCAY CAYCCNCCNCAYCAYTCNGAYCAYCAYCAYCAYCAYCAYCAYTCNCAYCAYYTNGAYTCN CAYMGNMGNGAYMGNGGNGGNGARGGNCCNGGNGTNGGNGCNGCNCCNTAYGAYGCNGCN GGNYTNGAYGCNGCNAARMGNAARACNYTNCCNYTNTGGYTNMGNGARGGNYTNGARAAR ATGGARAARGARAARCARAARCARYTNGARAARGARCARYTNAARAARCARAARGARATG TAY------GARCARCARGARGAYGCNATHAARGGNAARGAYAARGAYGARGARGAYGAY GAYGAYCARCCNAARGTNCCNMGNAARAGYMGNTTYGARTCNGAYGAYGARGAYGARGTN GCNGAYAARAARGCNGAYGAYGARGAYGCNGGNGGNGGNAGYGAYGAYGAYAAYGAYGAR GCNAARCCNGARAARTCNCCNGARCARACN---ACNGTNAARCCNTCNTCNCCNMGNAAR MGNAGYCCNTCNCCNTCNGARTAYATGACNGARGARGARAARGARATGGCNYTNATGATG AARGTNAARMGNYTNYTNACNGARACNYTNYTNGARGTNACNGAYCARGARATHMGNAGY GTNGCNAGYGARGTNTAYCARAARGARAARAARAARGCNCARAARGCNCCNGCNAARCAR YTNGCNAARTCNTCNGCNYTNGCNTCNYTNTCNAGYYTNGGNYTNGGNTAYGGNTCNGGN TCNGAY---------AGYGARGARGAYGARAARGAYGAYGAYGAYTCNGAYAGYGAYYTN GARGARMGNATHAARMGNAARAARGCNGARTTYGCNAARTCNCARAAYATHTTYAGYGAY TCNGARGGNGAYGAY---------GAYGGNAARCCNCCNACNGTNGGNAARAARCCNGAY MGNGAYAAYAARAAYAARAGYTCNAARGAR------GAYACNGCNTCNGAYYTNTCNAAR GAYMGNGARGGNMGNMGNAGYAGYMGNGAYGTNAARGAYMGNMGNAAYAGYAARGAYGGN ATHGTNAARAARGARAAYGAYTCNAARTCNAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTAYAAYGGNATHGGNYTNCARACN CCNMGNGGNAGYGGNACNAAYGGNTAYGTNCARMGNAAYYTNGCNTTYGTNAARTCNAAR AARGAYMGNGTNGAYTAYAARGAYGARGAYGARYTNAARAARYTNGARCARTCNATGAAY AARCARCCNAAYCARGARATHYTNGAYCAYGARMGNAARMGNAARGTNGARYTNAARTGY ATGGARATGCARGARYTNATGGARGARCARGGNTAYTCNAGYAARGARGTNATGGAYAAR GTNAAYATGTTYMGNAARATGYTNATGGCNAARGARGGNGTNTCNGAY---ACNCCNATH GARAARGAYGARCAYGGNMGNCCNATHGCNAARGARACNCAYCARYTNGCNGARGCNAAY CARYTNAARAAYGARAARYTNAARGARGCNTTYGGNYTNTCNGAYTAYGCNGARGGNAGY GCNTTYGAYCCNGAYMGNAARGCNAARGARGARCARGCNAARGCNYTNGCNYTNGCNCAR AARAARTAYAGYATHGTNAAYAGYTCNGAYGARGAYGAYGAYAAR---GARAGYTCNCCN GTNCCNAARAARAARAARAARAARTCNMGNCAYGARGAYGGNTCNTCNCCNGARMGNAGY AARGARAARMGNAARAARAGYMGNAARCAYAGYAARMGNGAYMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARGAYYTN AAYAARTCNMGNGCNAAYTAYGCNGARYTNGARTCNACNATHGGNAARYTNMGNGCNAGY YTNCARACNAAYACNTCNAAYCARAAYAARGAYMGNATHMGNATHCARGARYTNTCNGAR GARATHATGAARYTNGTNAARMGNCAYAARYTNTAYCARMGNYTNYTNTCNGGNCAYATH GTNATHCCNACNAARGAYMGNGGNTTYAAYCARTTYTCNTGGYTNGAYYTNACNGARGTN GTNTTYGARCARGTNACNGCNYTNATHGAYATHGTNCAYTCNTCNGAYGARAARYTNAAR CAYACNTAYGTNTCNTCNAARAAYCARGARGARGCNTTYGCNTCNYTNAARCAYGAYCAY GARGARCARATHACNAARYTNACNAAYATGGCNMGNGARMGNGARTCNGCNTGGCARMGN CARAARGARGARYTNGARCARCAYTAYAAYGARATGYTNTCNGAYATHCARTCNCARTCN AARAARAAYCARGCNATHGCNGAYCARGCNTGGGARAARGTNMGNGCNACNGGNAGYGTN CARCAYGGNYTNGARACNGARGTNGTNGARYTNMGNMGNGARYTNGCNGARTCNCARGTN CARGCNTCNTCNYTNYTNTCNGCNTGYGCNYTNYTNAGYGGNGCNYTNTAYCCNYTNTAY ACNAARGCNACNATGYTNTCNTCNCARMGNCAYATHYTNGARGAYYTNTTYTGYAAYTGG GARAAYTGYMGNGAYMGNGCNATGTAYYTNTGYTCNGTNYTNAGYTCNGGNMGNGARAGY GARCARGAYCARCCNGARMGNGAYAAYAARTTYCARMGNMGNMGNAGYCCNATHYTNMGN TTYMGNATGGGNGTNATHGCNGTNYTNGCNGCNAAYMGNYTNGCNTAYYTNGGNGCNAGY TGYAARAARTGYTTYGTNACNTAYAAYTCNTCNGTNAAYCARAAYGGNYTNACNGTNTCN ACNGGNGARGARGGNMGNAARYTNGCNGCNGTNAAYTCNAGYATHTGYAAYGAYCCNAGY GARCCNGTNTCNGGNTTYGGNCCNTTYTCNCARAARAARYTNGGNGCNTGGYTNACNAGY TCNGAYYTNYTNGARACNGTNATGGCNTCNATGACNGARYTNCARGARTCNYTNMGNATH AAYMGNAAYCARGAYAAYCCNACNGARGTNAARYTNGTNYTNAAYGCNGCNMGNACNTCN TTYACNAARTAYATHGAYMGNYTNGCNYTNTTYTTYCCNGCNTCNTCNYTNCCNGTNCAY ACNTCNGTNMGNGARMGNACNTCNYTNYTNMGNAARYTNGARMGNCCNYTNTCNCAYCAR YTNMGNAAYATGCCNTTYAAYTCNMGNGGNTGYYTNATHTCNTCNCARGARGTNATGAGY TGYYTNCARAAYCAYATHYTNGAYYTNACNCARMGNYTNCAYTCNGCNGARAARGARMGN MGNCARYTNYTNGCNGAYYTNAAYGAYYTNAARCARCARATHGGNGARGARAAYACNTCN YTNCARAAYTCNGTNGAYAAYCAYYTNTCNAGYAARGGNACNAARTAYGTNGCNATGGAR AARTTYGARAARGTNTGYGTNGARYTNTCNGGNGCNYTNMGNMGNGARCARAARGCNCAR GCNYTNYTNCARGARCARAGYCAYCARYTNTCNGARYTNACNTCNMGNYTNGAYGCNTGY GCNTCNGAYGGNATGTAYAARGARAARAGYYTNGTNCAYATHCARGARGGNATGACNGAR ATGCARGGNCAYYTNAARCAYAARGAYCARAAYYTNMGNCARATHAGYAARCARYTNGCN CAYATHGARTAYGARMGNGAYAGYYTNCARAGYAAYYTNAARGAYGCNGARAGYGCNYTN MGNACNGCNGCNAARGAYAARGARATHYTNGCNCARTAYATHAARAAYGTNGGNGGNGCN YTNGARACNGCNAARAARCARTTYYTNATHATHAGYGARCCNCCNCCNYTNTCNAAYGAY GTNTCNYTNTCNMGNYTNYTNYTNGAYGCNGAYYTNATHCCNATGGAYATHGGNAARACN GGNCCNGARYTNATHGCNYTNCARAAYYTNGTNGGNGGNTTYGTNGAYGCNCARCAYCAR GCNGTNAAYAARATHMGNTCNYTNGAYGARGARATHGCNTCNCAYMGNAGYCAYATHGAR TCNYTNAARAARGARYTNAGYAAYGCNGTNCARMGNGARTTYAAYCARCARYTNGARTCN GCNACNGAYGGNGCNTAYTCNATHTTYACNGAYCARGARGAYGAYYTNGTNCARYTNAAR ------CCNGAYACNGAYGAYAAYTCNTAYGARAGY------------YTNCCNACNCCN MGNAAR---YTNACNCCNCCNGTNTCNACNAGYAARAARTCNGCNTTYCAYTCNGTNAAR TCNAGYAGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNACNGTNGCNACNGGNGGNTTYATHTAYATG AGYCCNTTYYTNCAYCARTGGYTNACNGCNACNCARTAYATHGCNCCNYTNATGGCNAAY TTYGAYCCNTCNYTNAAYCCNAARTCNAAYATHTAYTAYYTNAGYACNGARGARATHTTY ACNGTNGARTGGAARGAYGTNTAYYTNCARGAYCARGARGAYGTNGGNGGNTTYACNTTY CARACNTCNYTNCAYAARAAYGGNACNATHAGYTTYGTNTAYAARGAYATHCCNATHGAY GCNACNYTNATHTCNGARGARAAYCAYCCNGTNAARGTNGGNYTNTCNGAYGCNTAYTAY AAYGAYACNATHATHGARMGNATHGGNYTNMGNMGNMGNACNATHTAYGARTAYCAYCAR GTNATHYTNAARMGNAGYYTNGTNMGNACNGGNGCNGTNATHTTYGTNCARCCNYTNCCN ACNTGYAAYACNYTNAAYGAYTGYCARTCNTGYACNAGYCAYGTNGAYGTNGAYTTYGAR TGYAARTGGTGYAAYACNATHGGNMGNTGYTCNGAYGGNYTNGAYTGGTAYMGNCARCAY TGGGAYAARTAYAGYTGYACNAGYYTNAGYACNAAYCARACNAARGARTGYGCNGGNYTN CCNCCNCCNACNAARCCNATHGAYCAYCCNATHACNCCNYTNGAYCAYCARGAYACNAAR TGYAARGGNGGNAAYTGY---GAYAARGAYAARGGNGTNCCNGTNGCNGTNATHGTNGTN TGYYTNYTNYTNGTNYTNGGNYTNGTNGGNGGNGTNGGNGGNTGGGTNTAYTAYGCNTAY ACNCAYCCNAAYTCNAARTCNGGNATGTGGYTNATHCARCAYMGNCCNAGYCARATHAAR GCNAARATHCARTTYTGGAARAGYAGYAGYAGYAGYGGNGCNAARTAYMGNGCNGARTCN GAYGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TGYCCN TCNYTNTGYGGNAARCCNAARYTNTTYTTYYTNGTNTGYTGYYTNGGNGGNTCNTAYTCN AARGCNGTNTCNMGNTCNGTNCAYGARACNGAYCAYGGNGTNTAYACNAGYAGYTTYGTN TGYAAYGAYCARGAYTTYYTNATHGGNTAYAGYACNGTNTCNGGNAAYGTNTCNTTYMGN GAYACNCARCARGGNACNTGGTAYATHACNGCNYTNACNCARGTNTTYYTNGARTAYCAY AARMGNGARAGYYTNCARCAYATGYTNGTNGCNGTNAAYGARCARGTNGCNAARAAYTCN CAYCAYTGYGCNAAYGARAAYGGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TTYGGNTGGCCNYTN ATHTCNGGNGGNTTYGTNAAYGARMGNTCNYTNYTNGAYTCNAAYGGNACNTTYTAYAGY AAYCAYCAYTCNTGYATHATHTCNGGNYTNGCNTTYTGYGGNGAR---GTNCARGTNGCN TCNATHYTNYTNMGNAGYCAYATHCARYTNGARAGYGARGTNAAYMGNGTNATHMGNGGN YTNACNGAYTAYAAYTTYCCNYTNGARMGNAGYTTYGCNYTNATGTAYGCNTGYGTNGGN MGNGGNCARCAYYTNTAYAAYAARCCNAAYGTNGARGCNGAYACNTTYMGNAARTAYTTY CCNAAYACNCCNYTNYTNGGNTTYTTYGGNAAYGGNGARATHGGNTGYACNTAYCCNCAR CCNGGNYTNATGCCNGTNTCNMGN---------TCNCCNAARCCNGAYCCNAARGTNGTN AARGGNGARGARGARYTNTCNCCNGTNCARATGAARMGNTAYYTNGCNGAYYTNAARTCN AARYTNGAYGARTAYMGNAAYACNCAYGTNCCNAARATHYTNCAYTCNTAYACNACNTGY ATHTGYYTNATHGCNYTNCCNGAYYTNAARCARAARMGNGCNGARGTNYTNTCNTGGTTY GGNAARATHYTNAARGAYGARCCNTTYCCNGAYTTYGARATGAAYGCNCARACNATHCAR YTNYTNCAYMGNYTNTCNGTNGTNAGYCARTAYAAYGARAARAAYACNCARYTNYTNATH GARGAYYTNAARAARAARTCNGARGARTAYAAYGCNGAYGCNAARMGNGTNGGNAGYATH YTNGARMGNYTNCAYYTNAGYCARAAYAAYYTNTCNAGYTCNGGNTCNTCNTGYGTNCAR GCNYTNGCNMGNACNGGNGCNTCNYTNGGNGTNAARGAYGCNTCNGAYACNTGYTAYATG YTNTCNATGMGNGARYTNCAYTCNGAYATGAAYGARAARGCNGAYAARYTNGAYTCNGAR AAYAARGCNYTNCAYMGNYTNYTNMGNAARGCNCAYAAYATHYTNYTNAARCARAGYTCN YTNGARAARGCNYTNGARGTNYTNGAYGARMGNTCNACNCAYGARGARGCNAAYATHGCN GARMGNAARAARGARACNGCNATHGTNAARAARGCNACNGCNGARAAYGAYATGACNATH GARAARYTNAARACNAARYTNACNCARTCNGGNYTNAGYGARTCNGAYTTYCAYGAYAAR YTNGTNAARAARAARGARGCNYTNGAYGCNYTNGARAAYGARYTNGCNCCNYTNAARGAY GARYTNCARTCNTTYTCNTGYYTNCCNCCNGAYGCNACNGARGCNAARGTNAARATHGAR CARYTNAARMGNGARYTNATHCARYTNCARACNCARATGACNCARTGYGTNGAY------ ------------------------------------------------------------ ---------------------------------------TGYCCNAAYCCNGGNAGYCAR GAYAGYTTYAAYYTNAAYCARTAYYTNGGNAARTGGTAYGARTAYGARMGNTTYACNGCN TGGTTYGARYTNGGNGTNAARTGYGGNAGYGCNCARTAYGGNATHAAYGAYGAYGGNAGY GTNAGYGTNGTNAAYGGNGGNTAYMGNAAYATH---------------YTNGGNTTYAAR GCNCCNACNTCNATHACNGGNMGNGCNGTNATHCARGAYCCNACNMGNCCNTCNGARYTN MGNGTNTCNTTYTCNAARTTYGAYMGNTCNACNGGN---GGNCCNAAYTAYTTYGTNGTN GARACNGAYTAYAAYACNTAYACNGTNGTNTTYTCNTGYACNGAYYTNCCNGGN---GAY TTYAGYYTNCARTAYGCNTGGATHYTNACNMGNGAY------------------------ ------------------------------------------------------------ ---------------GARGAYGARGGNAARGTNGCNYTNAAYACNACNTAYGGNAAYGAR TTYTAYGGNGARATGGARGGNGARGGNACNGGNGARCCNAAYAAYCARCARTTYGARGCN GARGAYAARAARGARGCNGAYAARAARAARAARAARAARAARMGNAARAARTGGYTNAGY ATHTGYYTNACNAAYTGYAARTAYGAYGTNGTNMGNMGNACNTCNMGNAARTTYGGNTTY AARGARGCNTCNGAYGAYGARGAYTGGACNYTNTAYTGGACNGAYTTYTCNGTNGCNYTN GARMGNGTNATGGARATGAARAAYTAYCARAARATHAAYCAYTTYCCNGGNATGAAYGAR ATHTGYMGNAARGAYATGYTNGCNMGNAAYYTNAAYMGNATGCARAARATGTAYCCNAAR GARTAYAAYGTNTTYCCNAARACNTGGTGYYTNCCNGCNGAYTAYGGNGAYTTYCARGCN TAYACNMGNCARAARAARAAYAARACNTAYATHYTNAARCCNGGNTCNGGNTGYCARGGN MGNGGNATHTGGGTNACNAARAAYCCNAARGARGTNAARCCNCAYGARCAYATGATHTGY CARGTNTAYATGAAYAARCCNTTYYTNATHGAYGGNTTYAARTTYGAYYTNMGNATHTAY ACNYTNGTNACNTCNTGYGAYCCNYTNMGNATHTTYGTNTTYAARGAYGGNYTNGCNMGN TTYGCNACNAAYAARTAYTGYGARCCNAGYCAYAAYAAYACNGAYAAYGTNTAYATGCAY YTNACNAAYTAYGCNATHAAYAARCAYAGYGARGAYTTYATHMGNGAYGAYGARGCNGGN AGYAARMGNMGNATHAGYACNATHAAYMGNTAYYTNAAYGAYAARGGNTAYGAYGTNGAY MGNATGTGGGCNGAYATHGAYGAYGTNATHATHAARACNGTNATHTCNGCNCAYTCNGTN YTNAARCAYAAYTAYMGNTCNTGYTTYCCNAAYCAYATHMGNGGNTCNGCNTGYTTYGAR ATHYTNGGNATHGAYATHYTNYTNGAYAARAARYTNAARCCNAGYATHYTNGARGTNAAY CAYTCNCCNAGYTTYACNACNGAYGCNCARYTNGAYMGNGARATHAARGGNACNYTNGTN TAYGAYACNYTNMGNYTNATHAAYTTYGGNGCNGTNGAYMGNMGNAARTGYYTNGAYGAR GARMGNAARMGNATHAARGAYMGNYTNYTNGGNAARTAYATHAARAARGARACNAARGAR GARATGGARGCNGCNCARAAYCARTAYATHGARCARYTNGARMGNTAYGARGAYAAYCAY YTNGGNAAYTTYMGNMGNATHTTYCCNGTNCCNGGNACNGAYAARTAYGAYAARTAYTTY CAYAGYAGYGGNACNYTNTTYCARGARACNGCNGCNTTYMGNGCNMGNCARGARYTNGCN MGNCARCARMGNGARGARYTNYTNMGNAARAARGARAARAAYGARATGATGYTNAARGGN AARGCNAARAARGAYGGNATGMGNCCNGARAGYCCNGGNMGNAARMGNMGNYTNAGYCAR MGNCCNACNYTNCCNYTNMGNCAYYTNAGYCARMGNCARCAYGAYGCNMGNGARATHGAR CCNGTNGAYACNYTNAARGCNCARGAYATHGTNGARGAYGARGARYTNGARMGNYTNTCN GGNYTNYTNCARMGNGAYAAYYTNGTNMGNGGNYTNGGNATHGTNGARCAYGTNTAYMGN YTNYTNCAYTGYACNCCNGGNACNATGGGNGTNGTNMGNCCNGARCARMGNCCNGGNCAR GTNGGNGTNGGNCAYAGYCAYACNYTN--------------------------------- ---------------------------GTNTCNYTNCAYTTYYTNAARGAYCAYCCNTAY YTNGARMGNCARCARYTNGAYCAYYTNTGYGGNGGNACNYTNATHCAYCCNTCNTGGGTN GTNACNGCNGCNCAYTGYGTNCAYMGNYTNYTNGGNGAYCAR---YTNGAYGTNCCNTCN AAYTGGGTNGCNGTNYTNGGNGARTAYCAYMGNMGNGTNGARGARACNTCNGARCARMGN YTNCCNGTNGAYGCNATHTTYMGNAGYCCNAAYTTYATGTAYGAYCCNCAYTTYACNGGN GAYATHGCNYTNYTNAARYTNAGYMGNCCNGCNATHYTNAAYAGYCAYGTNGGNGTNYTN CCNYTNGAYGCNGGNATHGAYYTNCCNGTNGGNGCNGARTGYGAYATHGCNGGNTGGGGN CARCAYACNGARGGNGGNGCNTCNGARGCNCARTTYGGNAAYGGNACNATGGTNCCNCAY TTYGTNTCNYTNAARAARTCNAGYMGNGAYAAYTGYGARMGNGAYTAYMGNAAYACNTTY TTYGCNATHGAYGAYACNGTNATGTGYTTYATGTCNCCNGARMGNAARGAYGCNTGYCAR GGNGAYTCNGGNGGNCCNYTNGTNTGYMGNAAYGCNTTYGGNATGMGNGTNYTNTCNGGN GTNGTNTCNGCNGGNGCNGGNTGYGGNMGNGCNAAYGTNTCNGGNYTNTAYACNMGNGTN GCNGCNTAYYTNCCNTGGATHMGNMGNACNATHGARTCNCAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GGNTTYGARGTN CARCCNAAYGARTAYGCNGGNATHAAYYTNGCNACNYTNYTNGTNATHTCNGGNAARGAY TTYTCNTCNTGYGCNGARYTNCARMGNATHGGNATHACNYTNAAYAAYYTNATHGGNAAR AARGGNAGYYTNTCNTCNYTNACNAAYTAYTGGGAYGTNGCNACNTTYTTYGARATHAGY GTNYTNGCNGARGAYTAYTCNAARGCNGTNCARGCNGCNGARTGYATG------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGNCARAARCCNTGYMGNATHATHATHCARGGNYTNGAY GCNGCNGGNAARACNAGYYTNYTNTAYAARYTNAARYTNGGNGARGTNGTNTCNACNATH CCNACNATHGGNTTYAAYGTNGARACNGTNCARAGYAGYAGYGGNYTNGARATHACNGCN TGGGAYYTNGGNGGNMGNGAYAARATHMGNCCNYTNTAYMGNCAYTAYTAYCCNCARACN GARGGNTTYATHTAYGTNATHGAYAGYGGNGAYMGNGAYMGNYTNGARGAYGCNYTNGAR GARYTNCAYGAYATGATHYTNCAYGAYGAYAAYACNMGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AGYGGNYTNATH GGNMGNAGYTTYGCNATGYTNTTYGCNAGYGCNGGNTAYGAYGTNATGATHTAYGAYYTN GARCCNAARCARACNTCNGCNGCNAARGCNGAYATHCAYGTNCARYTNGCNAAYYTNGAR AGYCARGGNYTNYTNMGNGGNAARYTNTCNAARGARGARCARTTYAAYAARATHTCNACN ACNGARAGYYTNGARGAYTGYGTNAARGGNGCNTTYTTYATHCARGARTGYGTNCCNGAR MGNYTNGAYATHAARMGNTCNYTNTGGTCNAARATHGAYAARATGGTNGAYGCNAARGTN ATHATGTCNTCNTCNACNAGYGCNYTNYTNCCNTCNGCNATHTCNGARGGNYTNGARCAY AARAAYMGNTTYATHGTNTCNCAYCCNACNAAYCCNCCNTAYTAYGCNCCNGCNACNGAR GTNGTNCCNGCNAARTGGACNGAYCCNGARGTNACNACNMGNACNACNGARGTNYTNAAR GARGTNGGNCARGTNCCNGTNYTNATHAARAARGARGTNAAYGGNTTYGTNYTNAAYMGN YTNCARTAYGCNATHATGGGNGARGCNTAYAARYTNATHCARGAYGGNGTNGTNAGYGCN AAYGAYYTNGAYYTNATHATGTCNGARGGNYTNGGNATGMGNTAYGCNTTYATGGGNCCN TGGGARACNGCNCAYYTNAAYGCNGARGGNATGYTNGTNTAYGGNGARMGNTAYTCNGAY ATGATHYTNGGNATHCARCARACNTTYACNCCNCCNGTNMGNATGGARGGNGAYACNYTN MGNACNATHCAYGARGAYATGYTNAARMGNGCNGGNCCNYTNGARGAYATHCARACNMGN MGNCARTGGMGNGAYMGNMGNYTNGTNGGNYTNGCNCARYTNAARGCNAARYTNGAYMGN GARGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNGCNACNTGYCCNTTYTGYCCN TTYGCNACNGTNATGCCNAAYGARGAYGAYAARGTNYTNAARTGYYTNAAYCCNGARTGY YTNAARGARTCNTGYMGNYTNTGYCARGARGARAGYCAYATHCCNYTNAARTGYAGYGAR GTNGARAGYAARGCNGGNACNAARATGMGNACNTAYATHGARAAYAARGTNACNGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNACNTGGTGYMGNAAYGTNACNYTNACNAARGCNYTNMGNCAR GARGAYCCNGAYCCNTCNGARGAYTCN------GAYACNAARCCNAARMGNAARGTNGTN GAYGTNGARACNAGYATHMGNTAYYTNGAYAGYAARGCNTTYATHGARGGNTAYGGNGAY AARCCNGTNTGGTTYCAYTAYMGNMGNAAYTTYAARGGNAAYATHGCNCCNCCNACNMGN AARAAYTGYYTNMGNAARGGNGARATHGCNACNGCNAGYCCNTGYCCNGTNTGYMGNGAY GARTAYYTNATHYTNGAYGCNAARAAYACNAARYTNYTNGAYCARTTYATHTCNCCNTAY ACNGGNGARATHTTYGAYTCNATGAARACNGGNYTNTGYCARACNCARCARMGNAARYTN ACNYTNGARGTNATGMGNGCNTGGGAYCARGGNTAYGTNGARATGAARGTNCCNTTYMGN GCNTAYAAYTAYGAYGAYTAYAARAGYTCNAARGTNYTNCARTGYTCNATGGAYMGNCAR YTNACNYTNTAYTGYGAYGTNAARGARCARACNAAYCCNGTNGCNAGYYTNTTYYTNTAY GGNYTNACNAGYCARCCNGTNGAYCAYGARATHAAYGGNCAYMGNAARCAYGCNTCNTCN GAYGCNGAYMGNTCNCCNGAYYTNGAYAAYGAYAGYGAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CCNTTYGARAARGTNGTN TTYGTNGAYTGYACNTGGAAYCARACNAARCARATHGTNAAYGAYGARMGNYTNAARGGN YTNAARAARGTNGARYTNAARTCNCARTGYACNCAYTTYTGGMGNAGYCARGAYGGNATG CCNAARACNTAYYTNTCNACNATHGARGCNATHTAYTTYTTYTTYAARGAYTTYCAYTCN ATHTTYGTNGAYCCNGTNTAYMGNAAYGARTAYGAYAAYYTNYTNATGTTYTTYTGYTTY ATGTAYCAYAARATHAARCARAGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TTYTTYCARCAY GTNACNTCNTGGCARAARACNCCNTCNGGNTCNMGNGARGGNAAYMGNGARTGYATHYTN TTYGAYTTYTAYGAYTCNCAYGAYGTNTGGCAYTTYYTNTCNGCNTTYAGYYTNTTYTTY TCNTTYATGATHYTNYTNYTNYTNGAYGAYAAYATHGCNYTNAARCCNMGNAAYCARATH CCNGTNTTYGAYTCNMGNGCNGARGGNYTNAAYACNGTNCCNYTNCCNGTNGARGARCCN ---------AARACNGAYGGNMGNAGYAGYGTNGARGTNAARGARAAYGGNGARTAYMGN GGNGARGAYMGNATGGAYGTNACNCARCCNGARGGNACNGARGAYAGYMGNGGNCARGGN CARTGGAARTCNCCNGARGAYCARTAYATHGCNTCNGCNCARYTNGCNCARAARACNGAR CARGARGCNYTNAARGARGTNCARGARGARMGNGAYMGNYTNYTNGARGARCARGCNCAR ACNMGNAGYTCNYTNAGYGCNGCNGARGARGARYTNTCNMGNAARAGYGAYYTNYTNGTN GCNGARAARGARATHAAYGCNTCNMGNGCNAARAARATHAARGCNYTNCARGAYGARYTN GCNACNYTNTAYGCNAARGGNCARGGNTCNGARGARMGNATHAARGAYYTNCARGARMGN YTNGCNGTNYTNGCNMGNGARAAYGARGARAARGAYCARYTNATHCAYMGNYTNAAYGAY GAYYTNMGNGTNACNAAYYTNAARYTNAARGAYATGGARAARCARYTNGCNYTNTCNCAR CARGARTGYGCNCARCARGCNGARGCNCCNAARTCNAARACNTGYGTNGTNATGATGTCN GAYATHAARTCNTCNTAYAARATGTTYTAYGAYAARYTNGTNACNTTYTCNGCNGCNATH CCNTCNAARYTNAARTCNTCNGCNCCNTCNGARYTNGCNTCNAAYGCNGGNGCNATGACN GGNATHATHAARCCNACNGAYGAYGCNTTYGARAARCAYAAYGTNGARGCNGTNATHAAR TAYGTNATGYTNGCNYTNATGGTNACNGARGARTAYYTNAARGGNGTNCARCAYTAYGTN AARGCNGAYGAYCARACNTGGTTYGAYGGNGARAARCARAGYYTNGAYTTYATGATHACN ATHACNAARATGTCNYTNGCNAAYYTNMGNYTN---GARGCNGGNAAYGTNGARGTNGTN GAYCCNGGNGTNGGNAGYATHAAYGCNGGNGTNTAYAGYGGNYTNTCNGAYGARGTNMGN TCNGAYATHACNGCNYTNYTNATHGCNYTN---------ACNTTYAARAGYAAYYTNAGY YTNGARAAYGTNTAYCCNAAYTCNGARATGGAYTTYYTNMGNMGNAAR---CARCAYGAR ACNGARACNAGYGGNACNGAYCARTTYTCNGGNTAYATHCCNATHGARCARYTNGARATH AGYCAYACNMGNAGYAGYGGNCCNGGNGGNCARAAYGTNAAYAARGTNAAYAGYAARGTN GARGTNMGNTTYCAYATHGAYTCNGCNTCNTGGATHCCNCAYTGGATHAARTCNMGNYTN GCNGARCARGARCARAAYMGNATHACNAARGAYGGNTTYYTNATHGTNMGNTCNGAYATG ACNMGNAARCARATGYTNAAYCARGCNGAYTGYYTNAGYAARYTNMGNAAYATGATHTAY CARGCNTCNGTNYTNCARGARGARYTNAGYGARGARGAYAARAARAARAARGARCARMGN ATGATGAARTCNAARGCNGGNGTNYTNMGNGARAARAARAARMGNTCNYTNATHAARAAR TCNMGNTCNAAYCCNGAYATG--------------------------------------- ------------------------------------------------------------ ---------------CAYGCNTTYAGYGTNAGYCAYCARGCNCCNGCNATHGAYGTNGCN TTYTCNCCNGTNAAYGAYCAYYTNATGGTNTCNATHGGNYTNGAYAARMGNYTNGTNYTN TAYGAYGTNCARGGNAARAARTCNATHAARACNATHGTNGCNGAYTAYCCNYTNACNTCN YTNGAYATGCAYGAYGGNAGYACNGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYATHCAYTTYGARATHCAYGARCCNGARTCNAARYTNYTNAAR GAYGTNGARCAYGAYGARACNGARYTNMGNTCNGARGCNAARGCNGTNAARYTNGARACN GGNGGNAGYYTNTAYAGYAGYACNGARTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GCNAGYTAYACNTTYCAYYTNATH GGNGCNYTNGCNAAYTGYYTNCAYTAYMGNGAYACNGAYAARAARYTNGCNTCNTCNAAY AARGAYGTNGAYTGGGGNAGYGARATGMGNMGNGCNGCNTTYYTNGCNTTYGCNTCNATH AGYGCNAAYGAYAARGAYATHMGNGARAARGTNATHAARCARGARGGNATGATHGARCAY ATHCARACNTCNYTNATHTGYGGNAAYGAYMGNGARGTNGCNGCNAGYYTNMGNTGYYTN CARTCNYTNACNMGNTCNGTNCARCARATHMGNACNGTNYTNCAYGAYAAYGCNGTNTGG AARCCNYTNYTNGAYAARGTNMGNTCNGGNAAYAARGARATHATG--------------- ATHYTNGCNATGTCNTGYYTNTGYAAYYTNGTNYTNGARTTYTCNCCNAGYAARGARGCN YTNGTNGARAAYCAYGCNGTNGAYGTNYTNTGYAGYYTNAGYMGNAGYGARGAYAAYATH GTNMGNYTNAAYGCNACNTGGGGNYTNATGTCNATGTCNTAYTGYGCNTCNGARGARYTN MGNACNAAYATHGTNAGYAARYTNGGNACNGAYACNYTNGTNAARMGNATHCARGAYCCN GTNYTNYTNATHMGNGARAARGCNYTNTGYATHGTNMGNAAYYTNYTNGCNGGNAARATG AGYATHGAYAAYACNGTNAARCARYTNGGNAAYGARGTNATHGARGCNGTNTTYAARATH YTNGCNGAYCAYGAYATGCCNTCNAGYATHGTNACNCARGCNYTNTGYGCNYTNAGYAAY ATGGCNGAYGGNCCNTCNTGYAARGCNTAYATHATHGCNAARACNGAYGARATHAAYGCN GTNGTNAARTAYYTNCARTAYCCNGAYAARGAYYTNCARYTNCCNGCNATHCARTTYGTN AGYAAYYTNGTNGAYACNAGYGAYGAYGAYTTYGGNYTNTTYCCNGGNGCNGGNTCNTAY CARMGNATGYTNCARYTNAARACNYTNGGNGTNCARACNYTNYTNGARAGYYTNGTNGGN ACNGGNYTNGARGARGTNGARGTNMGNGCNCARCARGCNYTNAARTAYTTYGCNATGTCN ACNTAYATHMGNMGNTAYGCNAARTAYYTNAAYGARAARGCNGTNTCNTAYMGNTCNATG GCNTTYGAYTTYTGYAARGTNAARMGNGGNAARGAYGAYGGNYTNYTNMGNACNATGAAY TCNGARAARYTNYTNAARACNYTNCCNGTNYTNCARCARCARYTNGAYGCNYTNYTNGAR TTYGAYTGYACNCCNAAYGARYTNACNAAYGGNGTNATHACNGCNTGYTTYATGYTNYTN TTYAARGAYYTNATHMGNYTNTTYGCNTGYTAYAAYGAYGGNATHATHAAYYTNYTNGAR AARTAYTTYGAYATGAAYAARAARCARTGYAARGAYGCNYTNGAYYTNTAYAARMGNTTY YTNGTNMGNATGGAYAARGTNTCNGARTTYYTNAARGTNGCNGARAAYATGGGNATHGAY AARGGNGAYATHCCNGAYYTNGCNAARGCNCCNGCNAGYYTNYTNGAYGCNYTNGARCAR CAYYTNGCNTCNYTNGARGGNAARAARTCN---GCNACNACNCCNACNGGNTCNAGYAAR CCNTCNGGNTTYACNACNGCNYTNAAYAAYATGTCNAGYAAYACNTTYAAYGTNAGYGAR GCNGARAARAARMGNATHYTNGAYGARGARAAYCARCARYTNCARAARCAYAAR------ ---------GARCAYAARYTNAARGARAAYACNTCNCCNCARAARTCNACNGCNGCNGCN GCNAAYAAYCCNTTYTCNAGYCCNGCNCCNGGNCARCARCAYCARCARCARGAYYTNTTY GGNTCNCCNGTNAAYAAYAGY---------GCNAARGCNAGYGAYGAYYTNYTNAGYYTN AGYTCNAAYCCNTTYGCNAGYAAYGTNCARGAYGTNATGGCNACNGCNTAYCARGCNCCN GCNAAYACNGCNCCNAAYAAYCCNTTYGGNACNCCNGCNTTYCARACNAAYGGNATHGGN GCNGCN---AAYTCNAAYAAYTTYGAYGCNGAYTTYGCNAAYGCNTTYAAYAAYACNGGN ACNAAYTCNCARGTNACNGGNATHGCNCCNTCNTCNGGNGCNCCN---------CCNGGN TTYGAYGCNTTYGGNGAYGTNATGGCNCCNATGAAYAARTCNCCNTCNCAYCARGCNCAR AAYAAYCARGGNGGNMGNTCNYTNGGNGGNGAYYTNGAYTCNTCNYTNGCNTCNYTNGCN TCNAAYYTNAAYGTNAGYGGNGGNACNGGNCARYTNAARAARGAYCAYCARTGGCARCCN AARGGNGARAAYAARATGACNGGNGGNAAYCARTTYCARMGNCARCCNATHGCNACNTCN ACNACNAAYCCNGCNCCNCCNCARTGGGGNCARCCNGGNTTYCARCARCCNAAYATGATG ---ACNGGNGTNCCNGGNGGNCCNATGATGTAYGGNCARCARATGGGNATGCCNATGGGN CARCCNATGATGCARCCNATGGCNATGATGGGNATGGGNCARCARCARCCNATGATGTAY GGN------GCNGTNCCNCCNMGNATGCCNGCNGTNCCNGGNGCNTTYGGNCARGCNCCN ATHCARCARCARGCNCCNGCNTCNCARACNAGYATHAAYGAYCCNTTYGGNGCNYTN--- ---------------------------------------------------GGNYTNGAR TGGATHGAYMGNGAYTGYAARMGNTTYAARATHCCNTGGCCNGAYAARMGNAAYMGNGTN TGGGCNAAYGARGARAAYATHATGYTNAARAARTGGGARATHTGYAAYGGNMGNTTYMGN GARGGNAAYGCNCAYGCNTGGACNATHTGGAARCARACNTTYMGNGGNGCNYTNAAYAAR AGYCCNTTYGTNAGYCCNGTNTCNGAYATGCAYMGNCARAARGAYCCNAAYCCNTAYMGN GTNTAYCARTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MGNTCNGAYCCNAAYCCNCCNCCNGAYCCNTCNTTYAAYCCNYTNTCNGAYTGG MGNMGN------------GARMGNGGNTCNGAY------------AARMGNGARGGNGAY CAYAARMGNCAYCCNMGNAAYTAYGGNGGNGGNGCNGAYYTNGCNAARGTNAARGAYAAY ATGAARACNYTNMGNGARMGNGARAARGARMGNCCNATGCARTCNMGNAAYYTNGARATG GTNATGACNGGNMGNGARMGNAARAAYCAYGARCARTGGAARCARGARMGNGAYMGNTAY GAYAAYGARMGNATHCARMGNCARATGGGNGAYACNGGNGGNTGGAARMGNGARTGGGAY AAYGARAARATHGTNYTNGAYTAYGAYGAYCAR------CAYCAYTCNAARATGGARCCN GCNAARMGNCCN------------------------------------------------ ------------------------------GCNGGN------------------------ ---------------------------------------------------------MGN ATHGGNAGYGGNMGNTTYGAYMGNGGNGAYAGYMGNGARGAYCAY---CCNCCNAARACN GTNTCNMGNGAYGGNAARGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GGNCCNTCNCARCARAGY------------------------CAY CAYCAYCARCAYCCNCARCAYCAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNGGNAGYAAYGCNACN TTYAAYAARATGGAYGCNATHMGNATHCARCARGARCARYTNGCNAARCARCAYTTYGAR YTNGAYYTNYTNCCNMGNTCNGCNTCNAGYMGNATHAAYGCNGARGARTCNMGNAARGAR AGYGGNGARAARATGGAYAARYTNATHGARCAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNATHGARGAYTGYCCN GAYGGNYTNMGNGAYAARTTYYTNMGNGTNTTYGAYCAYAARTGYTAYTAYTTYTAYYTN CAYYTNAARAARGARTTYAARAAYGCNCARAAYTAYTGYCARGCNAAYGGNGGNAAYYTN GTNTCNATHAARACNTCNAARGTNAAYAAYTTYYTNTGGAARAGYYTNAARGAYCAYTTY MGNGAYAAYGTNTGGATHGGNYTNTCNGAYCARGARAAYGARGGNACNTTYYTNTGGMGN GAYGGNAGYMGNATHGAYTCNAAYGCNCCNMGNCCNGARCCNGTNTAYYTNMGNMGNGAR AARCARCARCCNCCNACNYTNACNGCNTCNAARCAYCCNCAYGGNACNTCNCCNACNAAY GCNAGYCAYCCNCAYACNGGNCARGCNMGNCCNYTNTTYTAYGGNAAYGAYAAYAGYAGY GTNAAYMGNCARTCNMGNACNCARACNACNMGNCCNGAYCCNATHCCNGGNCARCCNTAY TCNGGNGCNCCNGCNCARMGNGTNGGNAGYGCNCCNYTNMGNAARATG------AAYAAY CARGGNACNATHMGNACNAAY------GTNGCNAAYMGNTCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNGAYGGN CAYGTNYTNAARTGYGTNAARGAYCARAAYGGNAAYCAYGTNGTNCARAARTGYATHGAR TGYGTNGAYCCNGARTAYYTNCARTTYATHATHGAYGCNTTYAARGGNCARGTNTAYAAY YTNTCNACNCAYCCNTAYGGNTGYMGNGTNATHCARMGNATHYTNGARCAYTGYACNGTN GAYCARACNCARCCNGTNYTNGAYGARYTNCAYGARAAYACN------------------ ---------------------------------------------------ATGAGYACN TCNGTNAGYACNATGMGNGCNGGNCCNACNAARYTNCCNGGNCCNAAYGAYAARATGACN AARGGNGAYATGAGYACNTCN------TCNCARTCNACNACNAARACNGAYGGNCAYTCN AARAARATGCARCCNACNCARGARCARYTNMGNYTNGCNCARATGATGAGYATGAAYCAR ACNGAYGCNGAYCCNAAYACNGTNAARCARYTNATGGAYATGACNGGNAARAGYGARGAY GARGTNGTNATHGCNYTNCAYGAYGCNGGNAAYGAYGCNGAYMGNGCNGTNATGTCNYTN YTNGARGGNGGNGARGARCARGAYGARTGGMGNGARTGYGGNAARAARAARAARAARAGY GCN------CARAARGARAAYACNAAY------CCNGARGARACNGTNGAYACNMGNAAY MGNGAYMGNGGN---------------------------GAYTCNCARGAYCARCCNCCN MGNMGNGGNMGNMGNAAYGGNGTNCCNCCNCCNMGNYTNGCNMGNGGNMGNGGNMGNGAR MGNGGNAAYTTYGGNGAYMGNGAYAARGARMGNGARMGNAAYAAYGCNGARGAYTGGGAY AAYGAYAARGARGAY------------------MGNGGNCCNMGNGGNGAYMGNGGNGAY MGNGGNMGNTTYMGNGGNMGNGGNGGNTTYAGYGGNMGNMGNCCNGCNGGNGCNATGAGY AGYGGNMGNGGNGGNMGNTTYAAYAAY------GAYMGNGARAAYMGNGGNTTYAAYMGN CCNMGNMGNTTYGARAARATGAAYAAYTCNCARCCNYTNGAYGGNCCNGARCCNGARATH GAYACNTGGACNAAYGARACNGCNGARACNAARGTNAAYAAYAARGAYACNGAYTGGAAY AGYTGGAAYGAYTCNTGGGTNAAYGARGARGAYCARTGGACNGGNACNYTNGARGARACN AARGTNTTYACNCCNTCNCAYGTNAARATHCCNGARCCNGARCCNGTNAAYAAYGARCCN CCNAGYTCNYTNGGNCARMGNYTNGAYGTNGGNAGYYTNTTYGARAGYGCNAARTTYGCN AARGCNCCNGAYTAYAGYAARCCNAGYGGNGAYTCNTTYATHAAYCARTTYAAYCARGCN GCNACNGARTCNATHAARAAYACNATHGGNATHGGNAAYACNACNMGNCCNCARATHCCN YTNTCN---------------CCNCCNGAYACNTCNGGNTCNYTNGGNYTNTCNAAYYTN GGNCARAARACNGTNCARGGNCARGGNAGYTCNGTNYTNCCNTCNYTN------CARCAR TCNGCNCARCARAAYTCNYTNCCNCAYGCNATGGCNCARYTNTCNCARATHTCNCAR--- ------------------------------------CCNACNTCNCARACNTCNAAYATG TCNCCNATGGCN---------------------------------TCNGCNTCNACNAAY CARGCN---CCNCARCARTCNMGNATHCCNGCNGTNGTNCARCARCARCARCARGGNATG ACNCARCARAGYATGCCNCARGCNAGYATG---AAYAAYATGCCNCARMGNCCNAARACN CARMGNTCNAARYTNCCNCCNCCNTCNAARATHCCNTCNACNGCNGTNGARATGCCNGGN CAYATHCCNMGNAAYCCNCARYTNGAYGTNCARTTYGGNYTNGAYTTYGGNTCNGARTCN TCNGTNCARTTYGGNTTYGGNGGNAGYGGNGAYAAYACNGCNGTNACNAGYTCNTAYTCN GGNACNACNAAYGGNACNAAY---------GCNAAYCAYYTNAAYCARGGNCAYATGGCN CARTCNGCNGGNGAYGGNAAYTCNGTNTCNCCNATHATGCCNTCNCCNTCNGCNGGNTCN GCNAAYGTNCCNTCNGGNATHGARACNCARGCNCCNAAYMGN---CARGGNGTNTTYCAY AAYTCNATGTAYTCNTCNCARCAYCARAARAAYGAYAGYCARCCNYTNGARYTNGARCAR AAYAARGTNAAYGARTCNATHCCNTTYYTNTCNTCNCARYTNGAYMGNAARTCNAGYCCN ATGGCNTCN---CARMGNCCNGGNCARACNAAYCARAAYYTNACNTCNGGNCCNATGACN TCNAGYAARAGYGAYACNCCNAGYGCNGCNGTNAGYAAYAAYTAYTCNGCNGCNAAYGGN TAY---TCNTCNTCNTAYCARAGYCAYTCNAARTCNTCNTCNGTNTCN------CAYACN GCNACNTCNCARCCNTCNCARACNTCNTCNTTYCAYGGNCARTAYCCNGTNAAYCARTCN TCNTTYCCNTCNAGYGGNCARACNCARTTYCCNACNCCNCCNAAYGCNACNCCNTTY--- CCNTCNGCNCARCARTCNCARTTY---GGNTCNGCNAGY------TCNCARAAYCARTTY TCNTCNGGNCARAAYCARTAYTCNGTNGGNACNTCNACN---------CAYCARCARAAY AAYCARTTYCCNTCNAGYGGNCARACNAAYTAYGGNAGY---GGNTCNTCNCARTAYTCN GGNTAYCARAAYAAYAGYTCNTTYCCNCCNCAYCCNCARTCNCARACNAAYTTYCCNTCN TCNCARAAYGGNGGNACNGGNGCNGTNYTNTAYCCNACNTCNACNCARTCNGGNGTNTCN TCNTAYACNACNCARTCNAGYTCNTAYCARTCNCCNTCNGCNGGNTCNTAYCAY---TCN TCNMGNGAYAGYTCNTCNGCNAGYATGAGYACNCARTCNGCNAGYGGNATGCCNTTYCCN AGYCARCCNCARAAYTCNAAYATGAARCCNGCNACNACNCARAGYAGYTCNAGYTTYAAY TCNCARAGYTAYAAY---AAYCCNGCNCCNYTNCARCCNTCNTCNYTNGCNAAYAARYTN GGNGARAGYYTNTCNAARATHTCNATGAARGAYTCNTCNTCNGTNYTNGAYAAYCAYCAR TCNTCNCARTAYGARCAYACNCCNTCNCCNGCNAGYGTNCCNACNAGYGTNAGYYTNCCN TCNGCNTCNAGYTCNGCNACNYTNTCNACNGGNACNAAYGCNATHTCNTCNACNTCNACN GTNACNACNGCNTCNCCNGCNTCNMGNGTNGCNTCNATGCCNTCNACNTCNGGNAARGCN CCNCCNAAYATHCCNCCNGGNGTNCCNYTNATGGGNCARTAYATHATGGGNCARAGYACN ATHCCNCCNTTYTAYAGYGTNCARCCNCCNYTNTAYGGNTAYGARGAYGTNCARYTNYTN CARCARMGNATGCCNGTNCARACNGGNAGYTTYTAYGAYGTNGGNGCNTTYCCNGCNGCN CCNGCNGGNTCNACNYTNCCNACNGGNMGNGAYCCNCARCCNCCNATHCCNAAYGTNCCN TTYTCNGGNACNTCNGAYACNAARYTNGCNMGNGTNGAYGCNCARAGYCCNAAYGCNTCN AGYCARCCNCARAGYGCNCAYTCN---GCNCARCAYCCNYTNTTYAAYTTYCAYTAYGGN TAYTAYTAYCCNTCNGTNTTYCCNGGNGCNGCNGGNYTNCARTAYCCNACNACNATGTAY CCNATHCCNCCNGTNACNAAYGCNGCNGCNCAYCARGGNACNACNGCNACNACNCARTTY CARAARACNTAYCCNTCNCAYGTNTAYACNACNAARGGN--------------------- ------------------------------------------------------------ ---------------TCNGGNACNACNGARATHACNCARAAYGCNTAYAAYAARTCNCAY GGNCARGCNGGNTTYGAYAARCARGGNTAYCAYGGNGGNACNCCNCCNCCNTTYAAYYTN CCNYTNGCNTCNGCNACNCARACNGGNCCNATGGGNGCNCCNACNACNCCNTAYGGNGCN CCNTTYYTNCCNGTNATGGCNGCNCAYCARCCNCAYTCNCARATGATGCAYCAYCCNATH CARCARGAYAGYAGYACNACNAGYTCNMGNGGNATGAAYCCNGCNGGNGGNCARGCNAAR TCNGGNGCNGCNAARTCNTTYGGN------CCNCCNTAYTGGAAYAAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGGNGTNYTNGAY ATGYTNAAYCCNGCNATHGTNYTNAARYTNMGNYTNGTNGTNTAYGCNGTNYTNATHTTY TTYTCNTTYTTYATHTTYGTNGGNGTNGCN------------------------GTNATG TGYCCNYTNTAYYTNAAYGTNAARAAYGGNMGNTAYGAYMGNGGNCCNAAYTCNAAYTGY GAYTAYCCNATGGCNATHTCNATHATHTTYCARYTNYTNTAYYTNYTNTTYMGNYTNGGN ACNYTNGTNYTNGTNYTNYTNGGNAARTTYACNGCNGAYATGGTNYTNTTYTCNGAYYTN GCNGARYTNATHTAYGTNATHATHGAYYTNGTNTCNTTYTTYYTNATHTTYATHGCNGCN TGYATHYTNTCNGCNGGNACNAAYTCNACNTGYAAYGAYGAYYTNATHGAYTGYAAYCAY CCN---------TAYTCNGCNTCNAARGCNGCNCARGCNGGNGCNTGGATHAGYACNTTY YTNTGGYTNTTYATHGGNATHTGYGGNTTYATHACNYTNTGGMGNGCNGGNAARATHCCN TTYYTNGGNGGNTCNGGNGCNGGNCARTCNGGNCCNAGYACNACNGGNCCNGAYCCNAAY CARCCNCAYATHGARCCNCCNCCNTAYAAYCCNGAYGARGCNCCNAARTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TTYAARAARMGNATHCARMGNMGNYTNTAYCAYGCNTGYGCNAGYGAYTGYGAYAGYGAY AGYGAYYTNGAYGGNYTNAGYACNTCNTCNYTNCCNYTNACNGARACNTGYATGGARTAY TTYCARGAYAGYTTYCCNGGNTCNGARGGNYTNGGNMGNATHGAYATGCCNATGGCNGCN ACNGTNACNAARMGNAAYGGNGTNTCNCCNTGYTCNATGGTNATGTCNYTNATGTAYGCN AARMGNYTNMGNCARMGNAAYAARCARTAYYTNCARTCNATGTCNTCNACNGAYGTNTTY TTYATHTCNATGATGATGGCNAGYAARTAYYTNTAYGAYGARGGNGTNGAYGARGARGTN TAYAAYGAYGARTGGGGNGCNAGYGTNGGNCAYGARACNGARGAYGTNAAYCARATGGAR ATGGAYTTYYTNAARGARATGGAYTGGCAYYTNTTYGCNAARCARGARGAYTTYGAYAAR GCNYTNACNGCNGTNGARMGNMGNYTNGCNYTNAARGARGGNYTNAARMGNGGNTGGTTY ACNTAYACNGARATGGCNGTNYTNYTNGAYTGGGAYCCNATHTGYAAYGTNTGGAAYCAR GTNGGNGTNGAYTGYACNAARATGGTNTCNYTNYTNTCNGCNGTNTAYGTNGCNAGYYTN GTNAGYATGATGGGNTCNGCNGCNGTNGCNGTNCARYTNTCNGGNCCNGTNTCNGCNACN GTNGCNGCNYTNYTNTCNYTNMGNACNTCNCCNGTNTCNCCNCCNTGYAAYCAR------ ---------TGYCCNAGYAARTTYAARTAYCARTGYATGACNAARAAYTTYMGNYTNTCN TGYATGTAYCAYTAYTTYTCNGARCCNCCNGARTGGTGYTGYCCNTTYTAYCCNCAYYTN GTNATH------AARAARTGYGCNTGYTGYCARTGYGCNGTNYTNACNTCNCARTAYGCN YTNGTNGGNCARTGYMGNMGNMGNTAYACNAARAARAGYTTYYTNGCNGTNTGYCARMGN GGNGGN---TCNTGGATHAAYYTNMGNTTYATHACNAARTAYYTNCCNACNAGYTGYTAY TGYMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGTNTGYGTN CCNTGYTTYYTNATHCCNGTNATHYTNTGGATHTTYCAYAARTTYATHMGNCCNTGGYTN TCNAARATHTGGAGYGGNTCNGARAAYTAYGTNACNAGYAAYYTNACNTGYCCNATGCCN CARAARAARAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CAYCCNGAYGGNAARGARATGCARATHAAYYTNACNGGNTTYYTNAAY GGNAARAAYGCNMGNYTNTTYGTNGCNGARYTNTGGACNCAYYTNTGYAGYGCNCARGAR AAYATHACNGGNATHCCNAAYGARTTYYTNGARCARAARAARAAYGARATHAARCARMGN CARGARGARCARGARMGNYTNCARGARCARYTNAARAARAARGARGARCARATHAARGAR CARYTNTCNAARGARMGNMGNGARYTN--------------------------------- GARAAYAARGAYYTNAAYAAYYTNTCNCCNGAYCAR------------CCNAARCCNGTN GCNACNAAYGGNATHMGNCCNYTNATGGAYGGNGAYAAYATGGTNGAYYTNAARCCNGAY GTNAARCCNGARCCNCARCARGARGCNGCNAGYGARYTNCCNGCNGARGTNGARGTNAAR AARGAYAARGARCCNAAYGARAARGARAAR------GARMGNTCNCCNGAYMGNMGN--- ------------AARGAYMGNMGNMGNCAYTCNMGNTCNCCNGAYMGNCAYMGN---CCN MGNTCNMGNACNCCNGAYMGN---CAYMGNMGNGARMGNGAYMGNMGNCCNGAYTAYGGN CAYMGNMGNTAYTCNCCN------------------------------------------ ---CCNMGNMGNMGNTCNMGNTCNCCNMGNMGNMGNTCNCCNCCNCCNAARMGNMGNTCN CCNCCNMGNMGNTCNCCNTCNCCNCCN---------MGNAARMGNTCNCCNCARAARGCN GARGCNGCNAARMGNAAR---------MGNTCNAGYAGYGGNAGYAGYTCNAGYGGNTCN GARGAYGAR---------TCNGGNAAYGAY------TCNTCNCARGAYAARGGNGGNGTN CARTCNMGNMGNAAYTAYMGNAARCAYGAYGARGAYAGYGGNAARGARTCNTCNGAYTCN TCNGAYGARGARGTNGTNAARGARMGNMGNMGNCCNTCNCCNCCNMGNGAYMGNMGNAAY GCNMGNAGYCCNTCNCCNMGNMGNMGNMGNTCNCCNCCNCCNTAYMGNMGNMGN------ ---MGNATGAGYCCNCCNCCNMGNMGNMGNTCNCCNCCN--------------------- ------MGNMGNMGNATGAGYCCNGTNCAYMGNMGNAGYCCNTCNCCNMGNMGNMGNTCN CCNCCNMGNYTNTCNCCNMGNMGNMGN---------AGYCCNCCNMGNMGNMGNCARAGY TCNGTNTCNCCNMGNMGNMGNMGNTCNTCNGCNTCNCCNCCNMGNMGNCCNCCNTCNCCN TTYCARGGNMGNMGNMGNMGNCCNTCNMGNTCNCCNTCNGAYTCNCCNGTNAARMGNMGN MGNCCNTCNCCNCCNCARTCNCCNCCNCCN---AARTCNAARAARAARCCNTCNCCNCCN CCNTCNGARTCNGARGAY------TCNTCNAGYTCNGAYGAYTCNTCNCCNTCNCCNCCN CCNCCNTCNAARMGNTCNGCNAARGGNAARGARCARCARCARCARCARCCNTCNAARMGN CCNCCNCCNCCNCCNAARCARTCNAARCARCCNTCNAGYGARGARAGYTCNTCNTCNGGN TCNGARGAYAGYGAYGARGARTCNGAYTCNGAYAARCCNGCNTCN---------CCNCCN CCNGCNAARCARTGGMGNGARGCNACNCCNCCN---------------MGNCARGCN--- ------------AAR---------------------------GCNTCNCARMGNCCNAAR ---------------------CARACNCCNCCNTCNATH---AARAGYAARMGNTCN--- ---------------MGNGGNTCNATGTCNMGNTCNMGN------TCNCCNGCN------ ------------CCNCARMGN--------------------------------------- ------------MGNGGNGAYMGNMGNCCNAGYCCNCCNCCNCCNGCNMGNAARAARGCN GGNTCNMGNTCN---------------------------MGNTCNMGNTCNCCNGCNGCN MGNMGNGAYMGNCCNCCNGCNTCNCCNCCNCCNMGNGGNMGNGGNGGNGGNTCNMGNTCN CCNCARGGN------------MGNMGNATGCCNCCNTCNAARGAYGARTCNTTYGCNTCN MGNMGNCCNMGNMGNGAYACNGAYCCNTCNGAYCAYGARATGGGNAARMGNGAYMGNMGN GCNGCNAGYCCNCCNMGNAARMGNCAYCCNMGNTCNCCNTCNCCNMGNCARGAYMGNGAY GGNGGNGGNAAYMGNGAYMGNGGNGGNGGNGGNAGYAARMGNTCNCCNCCNCCNCCNGAR MGNMGNMGNGAYMGNMGNAARGARAARMGNCCNCCNTCNTCNGAYAGYAGYAGYGGNAGY AGYTCNGARGARGARGARGARGARGCNGCNCCNACNAARCCNTCNGGNGARAGYAGYMGN TCNTCNGCNMGNCAR---GTNTCNCCNGGNGGNCCNTCNAARGAYGGNGGNGARAARCAR MGNAGYGAYMGNCAYMGNTCNGCNACNCCNCCNCCNCCNAAYGGNMGNGGNGCNTCNCCN TCNGCNGCNAARCCNAARAARGAYAGYAARCCNGTNGARTCNGCNAGYAAYAGYGARTCN GAR---TCNGAYTCNGAYAAYGCNTCNAARAARAARAARAARAARAARGAYAARAARCAY AARAARCAYAARAARCAYAARAARCAYAARCAYAARAARGARGCNCCN---------GAR AARGGNGARGAYYTNGARCARMGNYTNMGNGARAARGCNYTNATGTCNYTNYTNCAYMGN AARAARAARCARGCNTCNCARGARCCNGAYGAYTCNGAYAGYGGNGGNAGYAGYAGYGGN GARGARTCN--------------------------------------------------- ---------------------GGNGAYGAYTAYGARTTYYTNGAYYTNAGYGGNGCNGCN TAYCCNYTNTTYGCNAAYCARMGNACNMGNMGNGARACNTTYCAYTCNTGGGAYCCNACN CAYAGYCARAARCCNGAYGARYTNGTNAARYTNGGNTTYTTYTAYGCNGGNTAYTCNGAY TGYTCNMGNTGYTTYTAYTGYGGNYTNGGNYTNAARTAYTGGMGNCCNAAYGAYGAYGCN GCNTTYCARCAYGCNMGNTTYMGNCCNCARTGYAARTAYAAYCARTTYGTNATGGGNCAR GARTTYGTNGAYAAYGTNCARMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYGAYYTNAAYATHYTNYTNGTNGGNGCNGGNGAYATHMGNCAYATHYTNGCN ACNGTNGCNMGNMGNGGNMGNCAYAARAARMGNAARYTNAAYTTYTTYATHGCNGARTCN GCNYTNGARYTNTAYGCNMGNGAYATGYTNYTNATGATGGTNGTNYTNGARYTNCARCAR AAYATGGGNYTNCARGARAARACNCARGTNTTYYTNGARATHCAYGGNAAYACNYTNYTN MGNCARCARACNAGYGAYTAYATHCARAARATGGCNCAYCARYTNATHMGNATGGTNACN GAYTTYGAYTAYATGGARAARAARYTNCCNATHTTYGAYYTNAAYCARYTNMGNTAYAAR GARMGNGAYTTYYTNGARGGNATHYTNAARTTYTGGMGNAAYCARGARAARGTNAARAGY CCNTTYGAYATHAGYAARTGYTGGGAYYTNMGNYTNMGNCARCARYTNGGNGTNMGNTAY GAYAGYMGNGTNAAYGCNTTYGAYTGGGAYTAYAAYATGGARATGATHGARMGNGGNGGN TCNATHATHCAYYTNCARCARTAYAARTCNTGGMGNGGNGAYGGNATHGCNTAYACNATH MGNGARGGNACNTAYGAYGTNCCNAAYMGNTCNYTNTCNTCNGCNATGGTNTTYAARCAY GARGGNGARMGNTTYCCNMGNMGNGGNTAYTGGGGNGAYATGGTNGTNTCNCCNTAYGTN GCNTTYGGNGTNGARACNGARGARAARTCNYTNTAYAARAARCARAAYAARCARCAYACN AARACNGCNGARGAYGTNGCNGARTAYAAYGTNACNTCNYTNYTNCAYGARYTNGCNACN GGNGARAARTAYGARYTNCCNAARGTNGARGAYAARGAYGGNAAYAARGAR--------- ---CARCARACNGCNACNYTNGARGARATHATHGARGARCCNGAYGCNAARGAYGARGTN AAYGARGARAARACNAAYGAYGGNGGNGARGARGARGCNCARGAYTCNAARATHTCNGTN GAYAGYGARGAY------TAYGARTGGTCNCCNYTNGARGAYGTNAARGTNACNTTYYTN CCNYTNTCNTGYGTNAARGAYYTNGAYAARAARAGYAARTAYAARGAYTTYTTYAAYATH GTNTCNTTYTCNAAYAGYATGGTNCAYYTNYTNACNCCNGARYTNACNMGNACNTTYGCN GAYAARTGYGCNATHGTNGTNGARACNGCNYTNTTYATGYTNAGYYTNAARAARCCNGAR GTNCARGARTTYATGAARAARGTNACNGGNYTNGCNACNTCNGCNGGNTGYAARCCNYTN GAYGARGTNGAYGAYYTNCARGAYTCNTAYGCNACNTTYTAYTTYGARMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AGYAAYGCNATHGAY MGNCCNMGNGGNGTNTCNYTNGARAARGCNTCNTTYTAYCARYTNGAYACNGARTTYMGN TGYYTNACNAGYGGNAARGTNYTNCCNGCNGAYCAYGTNAAYGAYGAYTAYTGYGAYTGY GARGAYGGNTCNGAYGARCCNGGNACNTCNGCNTGYGCNAAYGGNYTNTTYTAYTGYGAR AAYAARCCNTAYAARGGNCAYTAYATHMGNTCNTCNMGNGTNAAYGAYGGNATHTGYGAY TGYTGYGAYGGNTCNGAYGARTTYGAYGGNATHATHGCNTGYTCNAAYACNTGYGTNGAR AARTAYGARCARGARMGNYTNMGNCARGARGCNTTYMGNYTNCARCARTCNGARGGNTAY AARGTNAARCARGARTAYATGCARCARGGNAARMGNGCNAARGAYGARAARMGNTCNAAR YTNAGYGARYTNGARMGNGARAARGARATHYTNATHAARGARAARGARACNGCNGARGTN TCNAARGTNGARGCNGARGARCCNGARAARGCNGCNATHGARGTNCAYAARAARCARTGG GARYTNGTNAARGARGARMGNCARAARGCNAARGAYTCNGTNAARGCNGCNCAYGCNTTY TCNACNYTNGAYACNAAYGGNGAYGGNAAYGTNGAYTAYCCNGARYTNATGAARCAYAAR GARTTYGAYATHGAYTCNGAYGGNACNGTNAGYGARGARGARGCNAARGARTAYYTNGAR GAYAGYGARCARGTNGAYGTNAAYGTNTTYTCNGARAARATHTGGCCNAAYATHAARGAR ATHTAYAARCCNGARGGNGAYGTNCCNNNNNNNNNNNNNNNNGANNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNGANNNNNNN---------GANNNNNNNNNNNNN---NNNNNNNNN GARGAYGARGAYGAYGAYTTYGAYGARTCNTCNTAYGAYATHGCNAGYGARAARYTNGAY GTNAAYACNCCNGARGARGAYAARGARCCNGARTAYAAYGARGARACNAARMGNYTNATH GARGTNGCNGAYCARGCNMGNAAYAAYTTYAAYGARGCNGARMGNAARGTNAARGAYGCN GARMGNGARATHGARGAYATHAARAARTAYYTNGARGTNGAYTTYGGNCCNAAYGARGAR TTYGCNTTYYTNAARGGNCARTGYTTYGARTAYACNGAYMGNGARTAYACNTAYMGNYTN TGYCCNTTYGAYAARAGYACNCARAARAAYAARAAYGGNGGNATHGARACNTCNYTNGGN ACNTGGGGNAARTGGCAYGGNCCNGAYGAYGAYMGNTAYGAYGCNATGAARTAYGARAAY GGNCARGGNTGYTGGAAYGGNCCNAGYMGNTCNACNCAYGTNAAYYTNCAYTGYGGNTCN ACNAAYACNYTNACNGGNGCNTCNGARCCNAGYMGNTGYGARTAYCARTTYGARTTYACN ACNCCNGCNAARTGYGAYGARCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GGNCARTAYYTNGTNTGYTAYGCNACNTCNCARGGN AAYTCNTCNTAYGARCARAAYAAYTCNGGNATHYTNGTNAGYCAYYTNAARAAYATHYTN CARACNCCNATGGGNGTNGARGARGTNTTYMGNAARYTNMGNGARGAYATHAAYCARGAY ATHYTNATGGARGTNGAYGARGARGGNAAYCARGTNMGNCARGCNCCNGARATHMGNACN ACNYTNTGYGARCCNMGNMGNTCNTTYCAYGAYCCNACNGAYACNACNGGNCAYACNCAR GCNTCNTCNCAYMGNCARATGATHTGGGARMGNGCNCAYMGNCARCCNGARGCNMGNAAY ATHACNGTNAAYTTYCCNGARTTYAAYGTNGTNATHMGNYTNGAYTTYAARGCNGARTTY TCNAAYGCNYTNACNATHTTYTGYTCNGTNGTNGAYAARGGNYTNTCNMGNATHTGYAAR AGYMGNATHTGYGARATHCCNGCNGAYGTNGCNGARAARGCNAARGTNTAYAGYATHGAR GARGGNACNGARGARMGNYTNTGYAARAAYTAYYTNCCNYTNCAYGAYATGCARMGNYTN MGNGAYGARATGYTNATHAARATHTGYGTNGTNTGYATHYTNGARGAYGGNACNGARATH TCNACNACNGCNGTNGARAAYYTNMGNYTNCCNYTNGTNTCNGAYYTNMGNYTNTGGMGN GARTGYCCNGAYYTNACNMGNCAYCARGARGCNGARGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARCCNYTNTTYGAR AAYGGNCARYTNTCNTTYYTNGGNCAYGAYGTNGARTCNATHCCNMGNTCNYTNATHGAR GAYTAYTGYAAYATHGCNCAYMGNYTNGAYYTNAGYTTYAAYMGNYTNYTNTCNYTNAAR GGNYTNGARCAYTTYAARTTYYTNAARGARYTNGTNYTNGAYAAYAAYGAYYTNGAYGAY TCNGTNTAYTTYCCNCCNYTNMGNGAYYTNCARACNYTNACNATHAAYAARAAYMGNYTN AARGAYYTNCCNTCNYTNYTNGAYCARYTNMGNGCNMGNTAYCCNAAYYTNACNTAYYTN AGYYTNYTNGGNAAYCARGCNTGYCCNAAYCARYTNTCNTCNYTNGAYAARGAYGAYGAR GAYTAYCARMGNTAYMGNTAYYTNGTNATHTTYAARYTNCCNAARYTNAARTTYYTNGAY TCNTCNCARGTNACNTCNGCNGARYTNTCNGARGCNMGNMGNGTNGGNCCNTTYATGCAR GTNGTNMGNCCNMGNGARGARCCNGGNGARGARAAYGARCCNGARCCNTCNCCNYTNCCN GAYACNAARTAYACNCCNYTNCCNGCNGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNAAYAAYGTNMGNTCNGTNATHGARYTN TTYTGYAARYTNYTNTCNGAYAGYGAYATHTCNGAYGTNMGNGCNGARACNYTNMGNCAR GGNAARTTYGAYMGNGAYGTNATHACNAARATGATGTGGACNGTNYTNTAYGAYGTNGTN TGYTTYYTNGAYTCNMGNTCNGAYYTNGCNTTYGTNAARTGGAARYTNCARAAYTGGGGN TAYYTNTCNAARTCNTTYGCNGAYYTNCCNCCNAGYYTNGCNTTYGGNAGYMGNGARATH YTNYTNGCNYTNGGNTGGGTNGTNTAYACNCARCARATGTTYAGYGARATHATHMGNMGN MGNACNAGYCCNYTNCAYMGNGAYTTYYTNTCNTTYMGNAARATHCCNGTNGAYGTNGGN ATHCAYCARACNTTYCARYTNGGNCARGAYYTNCCNGCNAARGARAARYTNCARMGNCAR YTNYTNYTNTGYGGNAARYTNAARYTNAARYTNMGNMGNYTNTAYTCNTCNCARCARGAR YTNGTNCAYYTNMGNGARACNATHCAYAARTGYACNGTNGGNGTNAGYGTNCARCCNGAR YTNAAYCAYYTNACNGCNYTNGARGTNTTYYTNYTNMGNCAYCCNGARAGYYTNGARMGN ATGYTNGGNATHYTNGARGARGAYAAYGCNAARYTNAARMGNYTNYTNGARTGGAARGAR AARGAYCAYGTNTTYTGGGARTGGATGGAYAGYGTNYTNACNYTNCAYGCNCARGARGGN GARMGNGAYTCNMGNCARGARGCNATGGGNGGNACNGARTCNGTNTTYYTNGAYATHCCN TCNGAYATHGGNAAYCARATHTCNGGNYTNMGNTCNCAYGTNMGNGAYTTYATHYTNGGN CAYGARGARMGNATHGARGCNYTNGARAARYTNGTN------TCNAARGTNTCNCCNATG GARATHGARYTNGCNAARTTYCAYGTNGAYAARGARYTNTTYGARYTNTCNCARMGNTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TCNTCNAARYTNGAYYTNMGNAAR TCNTCNTGGYTNAAYGGNTTYATGATGTTYAGYCARGTNCAYMGNMGNAARTTYATHMGN GARAAYCCNGGNGTNCAYACNGCNCARATHAGYAARATGATGGGNCARGCNTGGMGNGAY ATGTCNMGNGARCARCARYTNTTYTAYMGNGARCAYGCNAARYTNTGYTCNCARGARYTN CARCARGTNYTNGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNCCNCCNTCNCAYMGN MGN--------------------------------------------------------- ------------------------------------------------------------ ---------------------------ATGTGGTCNCCNAAYGAYGCNGGNGTNGTNTTY TGYGCNTGGGAYCAYGARCCNTAYMGNYTNGGNYTNAARCAYTGYTGYCARMGNAARAGY GGNYTNTTYTAYTAYGAYYTNGARAARGGNACNGTNGARYTNYTNAGYGCNGARGGNMGN GCNGTNMGNTTYCCNMGNTTYAGYCCNGAYATGAGYMGNYTNGCNTAYTTYGAYACNCCN GTNGGNGGNGGNCAYCAYCARTGYTGYMGNYTNYTNATGATHGAYTGGGCNTCNMGNAGY GARMGNGTNGTNATHGAYATHGTNMGNCAYGCNCCNGCNGARTCNTTYCARGGNGTNTTY ACNGCNAAYATHCCNMGNAAYATHTGGTTYAGYGAYAGYATHCAYYTNGCNTTYTCNACN GCNTGGMGNACNTCNACNGCNGCNGTNATHGTNAAYACNGAYACNGGNGAYATHAARMGN TTYCARCAYGGNATHGAY---YTNAAYATGACNGTNYTNAGYGTNAARAARAGYTGYYTN YTNYTNGCNTGYTCNTCNATGACNACNCCNTGYCAYYTNATHYTNGCNGAYYTNGARGAY YTNAGYMGNCCNGAYMGNACNTCNTGGATHTAYYTNGAYGGNACNCCNGAYGARATGGAY TGGYTNTTYACNTTYGARGTNYTNAAYCAYAARCCNATHGGNGARMGNATHAGYGCNATH AAYGCNAAYYTNGAYTAYGARAGYATHYTNTGYYTNCCNACNAARGAYAARGAYGGNACN YTNCCNCCNYTNATHGTNTTYGTNCAYGGNGGNCCNCAYGTNGGNTTYGAYACNTCNTAY AAYCCNATHACNAAYTTYTTYTGYATHTGYGGNTAYGCNGTNYTNATGGTNAAYTAYMGN GGNTCNTGGGGNTTYGGNCARGAYTGYATHGAYTCNYTNYTNGGNCAYGCNGGNGAYCAR GAYGTNAARGAYTGYCARAGYGCNGTNGARTCNGTNYTNTCNAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGGGNGARACNMGNGARCARAARGARGCNTTYGTNACNYTNGCN ACNAAYGAYACNTAYACNYTNGGNTGYYTNGTNYTNGGNAAYTCNYTNMGNCAYGTNGGN ACNACNMGNAARYTNGTNGTNATGATHACNGAYGGNGTNTCNCAYTCNATGMGNGAYCAR YTNAAYGCNYTNTAYGAYGARGTNGTNGTNGTNAAYGTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TAYGGNTAY ATGTCNGGNACNGCNCARAAYTTYTTYATGTGGTTYGTNGAYGAYATHGGNGGNACNCCN GTNAAYYTNGCNYTNATHATHGTNGTNAAYTGYATHTCNTCNATHACNATGYTNMGNTTY ACNGGNMGNYTNYTNAARMGNYTNGGNTCNMGNMGNACNATGTAYYTNGTNYTNGTNACN TAYGCNGTNMGNTTYYTNGGNGTNTCNTTYATHCARGTNCCNTGGTGYATHYTNCCNYTN GARYTNYTNCAYGGNGTNACNTAYTCNGTNTTYTGGGCNGCNGCNTCNGGNTCNACNAGY AARATGGCNGCNAARGGNACNCARGCNACNTGYCAYAGYATHGCNGGNGCNATHTAYTGG GAYYTNGGNMGNGGNYTNGGNATHYTN--------------------------------- ------------------------------------------------------------ ------------TCNTCNGCNACNGAYAGYATGAARYTNYTNGCNAARAAYAARACNGAY GAYCARAARACNACNGTNATHGCNCCNGCNTCNACNACNGCNGAYAARAAYGAYGAYGTN ATHAARGAYGTNYTNGAYAAYGARGAYAARGAYATHAGYCAYTAYATHTAYCARGGNGAY ATHTAYGCNGTNCCNGAYAARGTNAAYTCNCCNMGNGAYGAYAAYAAYGAYGARAAYCCN ATHATHTCNTGYATGAARAARATGGTNGTNGARAARACNMGNACNAAYAGYCARAARTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TCNTTYCARGARACNYTNCCNGCN GGNGGNYTNAARCAYGARGARCCNCARCAYMGNGGNYTNGAYCARYTNTAYTCNGAYTTY YTNGCNCARCARACNMGNYTNTCNACNAARCAYTAYATHTTYCAYTCNATHACNTCNAGY YTNTTYGAYTCNTTYAARAARGTNATGGGNGAYGCNTGYACNYTNGAYTCNTTYGCNTGY MGNYTNCARGARTGGCARACNMGNTGYYTNTCNYTNCCNGTNYTNMGNAARNNNATHYTN AARGGNATGYTNAARYTNACNMGNGAYAGYAGYATGGCNTCNYTNCAYATGACNTCNGGN CCNAARCARAARAGYYTNTAYCARTTYCCNTTYYTNTGGGTNGCNYTNATHYTNTGYGGN YTNCCNYTNTTYGCNACNATHTTYTGYGTNACNTGGTCNGTNYTNTTYAAYTTYGARGAR TCNACNMGNACNCAYTGYMGNGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CAYTCNAGY TTYATHGGNYTNTCNGAYTTYAAYATHGAYCAYYTNCCNGARGCNYTNAARMGNCARGAY GTNYTNGAYTAYATHAARGCNGARGCNAAYATGACNGTNMGNGTNAARGTNAARTAYACN AGYAAYAAYMGNCCNGAYTCNGAYGCNTGYGCNMGNCAYMGNGGNACNMGNTTYGCNMGN ACNGCNTCNGGNTAYGTNYTNGAYAAYCCNGAYGCN------GTNAARCCNGTNCCNTGY ACNGTNCCNAAYTGYCAYMGNGARAARGGNTCNGARCAYYTNATHTAYGGNGAYYTNAAR ATHTTYACNAAYAARCAYGTNATHTAYGAYGARGARGARYTNGCNAARTCNACNGTNGAY TTYTTYTAYAGYGAYGAYAARAARGGNATHATHCARGARTAYGCNGTNCARYTNTTYTAY YTNAAYGCNAARTCNGAYAARGCNTTYATHAARGTNACNATHCAYGAYGARGAYATGYTN MGNMGNYTNTAYCARYTNGAYTGYGAYMGNGCNTTYCCNCARTCNGTNATHGAYCAYTGG ACNCCNTAYGCNATHYTNATHTCNCAYCCNCAYGGNATGCCNAARAARATH--------- ------------------------------------------------TTYTCNAGYACN ACNAGYYTNAAYTTYTTYGGNTGYCCNGGNCCNATHCAYAGYAAYGTNYTNAARGCNYTN TGGGAYTTYGCNAARATHGTNYTNTTYYTNYTNTTYGTNYTNATHATHGTNYTNGCNTTY GGNGAYGCNTAYCARATHTCNTCNACNAAYCARYTNYTNGCNACNGTNGTNGGNGGNATH ATHCCNTTYTTYTTYAGYCARTTYTTYCARTCNAAYTCNGAYGTNTGYGGNTTYAAYAAR GAYAGYGTNCARTTYCARACNGARTTYCAYGCNGCNATHAAYGARTTYGARCARGCNTGG CCNGTNTAYGAYATHATHCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNTGYAAYATHAAYCARCCNGTNTCNATHYTNGAYTAY TGYCARCARGARTGGAARGGNGAYACNCCNAARGCNACNGCNATHMGNCARGGNTAYCAY AAYATHCCNTCNGTNYTNGGNTGYCARMGNATGTGYGTNATHMGNGGNGAYAAYTAYTGY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATHGCNACNGTNGAYGAYATGGGN ACNGCNMGNATHTTYYTNTAYGCNTTYGAYCAYATHTTYTTYGTNAARGCNYTNAAYGAR AAYAGYCCNGARGGNACNTCNAARATHYTNTGYCAYAARTGYGARGCNTCNAARGARGGN GAYTAYATHGGNGTNTCNTTYGARAAYACNAGYAAYMGNGARATHTGGYTNGARGTNCAY AARYTNCCNGTNGARAGYTGGYTNAARGAYTTYGARGCNATHCAYGCNGCNATHAAYAAR CARAARGAYGAR---GARAARTCNTCNCAYACNGARATHTCNGGNCARGTNTCNGARACN GARCARGARACNGCNCCNACNCARACNGARGARGTNAARAGYGAYGARTCNATHGTNAGY GTNAGYGCNGTNATHGARAARYTNGGNACNAARTTYAGYCCNCCNTCNATGGTNYTNMGN GTNAARCCNCCNGCNCARMGNTTYCCNGCNCCNAAYAAYTCNTCNAGYYTNGCNTCNGCN GTNTCNAARGTNGAYCARGGNGAYGTNYTNGGNACNGGNACNAGYCAYGTNYTNAGYGCN GCNCAYYTNGAYTCNMGNGAYTGYATGTTYAARCAYMGNCAYGARAGYYTNYTNGARTTY YTNCCNGARGARGARGARGARAAYACNACNTCNGTNAAYATHCAYTTYACNAAYACNAGY MGNATGATHCCNTAYGGNATGGARCAYGGNGCNCCNCCNAAYAARCCNGTNTCNGTNGCN GTNTGGTGGTCNGGNACNCARCAYATHTGYCAYTAYTCNYTNYTNMGN---ACNGGNAAR GAYGTNGARTTYAARCCNGAYATGGTNTGGCCNTGYTCNGAYACNATHACNTGYTCNACN YTNAGYCCNTGYGGNTCNCAYATGGCNGTNGGNYTNGCNAAYGGNAAYYTNGCNYTNTGG GAYTAYCARATGGGNYTNCCNAARGCNGTNYTNACNGTNTGYGGNAAYGGNGGNGTNMGN GARYTNMGNTTYYTNGAYCCNAGYYTNTTYCCNTCNGAYCCNCCNGARTAYCCNCCNTAY CCNGTNTCNTCNGCNACNTTYATHYTNGCNGARTAYAARGAYGGNACNCARGCNYTNTTY GAYACNTGYGAYGGNAGYCARCARATHCCNMGNATHATHGCNACNGTNCCNGARAAYGAY GAYGAYGTNCARACNYTNATHGARGTNATHCCNGAYYTNCCNGARYTNATGYTNTTYGTN AARAARAAYGGNTGYYTNTAYATHAARGAYGTNGGNACNGGNGCNTCNYTNTGYCARGTN GTNYTNCCNTCNACNCAYTCNATHCARACNCCNTGGAGYCCNATHTTYGCNATHGGNGCN GGNAGYCAYGTNYTNTAYYTNAARGCNGARGGNCARGAYGTNAGYGARGAYGGNGARGTN AGYGAYYTNTCNTGYYTNTTYAARTTYAAYYTNMGNGARTAYCCNATHYTNGARGARTAY TGGGCNMGNCCNMGNGARAARTCNGAYYTNAAYGTNTAYACNACNTGYCARCARMGNYTN GARTCNYTNATGAARGARMGNYTNCARCARCARGCNATGMGNAARCCNMGNATGCARYTN CAYTGGGGNCARYTNMGNGGNGARYTNGAYATHATHCARAAYGCNMGNGARATHCCNGTN GAYACNYTNMGNYTNTCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNAGYGTNMGNTTYATHTCNGAYAGYMGNACNAAY AARCARTCNYTNGGNTTYMGNYTNYTNGTNYTNCAYGCNACNTCNGARAGYGARYTNCAY YTNMGNATHCAYGARGCNMGNAARATHGARGARCARAARAARGARAARGAYGAYAAYGAY AAYAAYGARGCNYTNYTNATHATHYTNTCNTCNACNYTNYTNGTNYTNYTNYTNTGYATH ATHGCNATHATHATHYTNTAYMGNMGNGCNCCNGCNTAYGCNACNCCNCCNACNYTNYTN CAYMGNGTNGGNYTNGARTCNAGYTCNACNGGNTCNTCNTTYCCNGCNGAYTTYACNAAR CCNGTNCCNYTNGCNGTNATHTCNCCNGAYMGNMGN---------------------AGY CCNTGGGGNAARCARAAYACNGTNAAR------CCNTGYTCNYTNGCNGAYGTNATGAGY GARGARYTNGCNTCNGARYTNCARAAYAAYCARGARMGNCARTTYYTNGARGAYYTNAAR YTNAGY---CARGCNACNGTNGCNGCNTCNTCNGTNTCNCCNYTNAGYGCNGAYACNGAR YTNACNGAYGCNGARYTNGCNGCNAARYTNGCNGCNGARGARTGYGAYCCNAAYCCNAAY GAYGARATGATHGCNYTNATGYTNCARAARCARTAYGAYMGNGARTAYGAYGCNGTNYTN TCNAARMGNGARCARAARTAYAAYGGNAAYTGYAARGTNGCNGTNTCNTTYGAYAAYTTY AARMGNAARCAYCARGCNGAYTAYGARCAYGCNGARGARGAYGAYGAYGAYGAYGAYTTY TAYGARGARGAYYTNCCNCARCAYCCNCARMGNTCNCARTGGGARAGYGGNTCNCCNAGY ATHGGNAAYMGNGGNTAYGCNAARCARGGNGAYACNATHATHACNAARCAYGAYAARACN ATHTGYGARMGNMGNAAYGCNCARMGNYTNATGCARTTYCCNCCNGAYTTYGAYAGYGGN GAYGGNGARGGNATGGAYATGCAYYTNCCNAAYMGNGTNTAYAAYAARYTNAARCARCAY TCNYTNTCNGARAAYAARAARGGNCAYAARGTNYTNGAYAARAARGAYCAYTCNACNGCN ATHAARGCNGTNGAYGARAARACNMGNATHYTNATHTTYAARATGATHAAYTCNGARTTY YTNACNTCNGTNGAYGGNGTNGTNAGYGARGGNAARGARGCNGTNATHYTNAARGCNATH GGNGGNMGNAARGAYAAYGTNGARYTNCCNAARGAYGTNATHYTNAARGTNTAYAARACN TCNATGAAYGARTTYAARACNMGNYTNAARTAYATHCARGGNGAYTAYMGNYTNTCNAAR GAYGTNYTNAARAARTTYAAYGCNMGNAARATGATGCARATGTGGGCNGARAARGARTTY YTNAAYYTNMGNAARYTNMGNMGNCAYGGNGTNYTNTGYCCNGAYCCNYTNGCNCARAAR AARCARATHYTNGCNATGACNTGYGTNGGNGGNGARMGNCCNGCNCCNAARYTNAARGAY GTNGCNTTYAGYACNGARGAYTTYCARGAYGCNTAYGARCARACNGTNGARYTNATGAAR GCNATGTTYGAYMGNTGYAAYATGGTNCAYTGYGAYATGAGYCCNTAYAAYYTNYTNTGG CAYCARAARCARGTNTGGGTNATHGAYGTNGGNCARGCNGTNGAYMGNGAYAAYCCNAAY TCNAAYTCNTTYYTNTTYMGNGAYTGYMGNAAYATHTCNGARTTYTTYAARCARGGNGGN GTNCAYGAYGTNCCNTCNGCNGARGGNYTNTTYAAYGARATHACNAAYTAYGCNTTYGAR GGNGARGGNAARGTNTTYGARTCNCARGCNCAYMGNTAYGAYGARGARGGNTAYGCNTTY GAYTTYTTYTTYGARYTNTCNGARTCNGCNMGNTCNCARGCNTCNGGNACNGCNGAYAGY AGYGGNAGYGARGARAAYGARGAYGARGARGARGARGARGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARAAYAARTAYMGNYTNGAYTTYAAYAARACNATGTAYTCN CCNGCNCCNGGNGAYAARGTNAARGTNYTNTTYACNGAYMGNAAYMGNTCNAARACNACN ACNMGNATHGCNATHGCNMGNGARMGNMGNGARGCNCARACNMGNYTNGAYGGNATHCAR YTNGGNAAYCCNTGGCAYGTNAGYGARGAYMGNCCNGGNYTNGARACNTCNATHTAYATH CCNCCNGGNGGNTCNGTNGAYTCNGGNGCNATGTTYAAYATHATHATHMGNTAYACNAAR ACNCARCARYTNTCNACNTAYATGACNAGYTAYTAYACNCCNGTNAARGTNGGNTGYACN AARYTNGTNGCNGCNMGNYTNAGYCCNTCNGCNCARCAYATGGTNTTYYTNYTNYTNTTY CCNGCNTTYCCNCCNAARGAYGCNCAYYTNATGGTNGTNGTNYTNGARYTNTCNTCNATG AARYTNMGNAARTTYMGNTAYGAYCAYYTNYTNTCNGAYCARCARCAYMGNGAYATHGCN TCNGAYAARGTNTGYTCNGCNGARATGTGYCARGTNTAYGGNCCNACNGGNGCNGAYTAY YTNTTYYTNACNGTNGGNGGNGAYTTYACNTGYGTNTCNYTNGCNACNGGNTGYGGNGTN YTNMGNATHGAYAAYCCNGCNMGNCCNAARGTNGGNAAYTTYMGNGGNYTNGTNATHGAY GARAARCARTTYCCNYTNTCNMGNGTNCARAARGTNGCNTTYGTNGGNAAYATGGGNTCN YTNTAYGCNGTNTTYTAYGAYCARAAYACNTGYGGNYTNAARATGYTNMGNYTNGARGAY GGNAAYAGYCAYGARGAYTCNATHATGGTNTCNAARGCNTTYAARCARTGGGARMGNTAY CARAGYACNCCNATGGARYTNMGNATHAAYCCNGTNGAYTGGGCNYTNCCNGAYATGAAR CAYAARYTNGCNGARATGMGNAGYYTNGTNYTNTCNYTN------ACNGARGTNGAYGTN GGNATHACNGARTAYYTNGGNTCNCARACNCARTCNTTYTCNGCNGTNATHAARCARMGN TAYTCNGAYTTYATHGTNAAYGARATHGAYGARAAYGGNAGYGTNGTNCAYYTNAARAGY ATHAAYCCNGTNGARGAYACNGARGAYGARGARGARGAYAARAARGCNACNAAYGARTCN YTNGAYGTNYTNAGYGARACNGAYMGNGARGCNATHCARAARATHGTNACNGAYMGNAAY AARGARGCNTCNCAYAAYATHYTNGCNCCNGARGAYAARTCNATGMGNACNAARATHCAY YTNACNATHAARCARACNTTYACNCARYTNGARACNTCNACNACNGARAAYGARGARGGN CARAARGTNATHAARGTNGCNTGGMGNAARGGNAARACNMGNGAYGTNATHMGNGAYGAR TGGCCNCARTCNAARAARTCNTGYMGNTAYGTNMGNTTYGTNYTNTAYAARGARAAYAAR GAYACNATGGAYGCNATHGGNYTNATHGCNAARAAYYTNAARGTNMGNGARAGYATGTTY CARTAYGCNGGNAGYAARGAYAARMGNGCNAARACNTCNCARGARATHACNGCNCAYMGN ATHCAYCCNAARAARYTNGTNAAYYTNAAYAARGTNYTNTGGAAYATGGGNYTNGGNGAY TTYMGNTAYGTNGARCARCCNYTNCARYTNGGNCARYTNTCNGGNAAYMGNTTYACNATH GTNYTNMGNAAYATHCARGCNAGYGTNGAYACNGTNGAYACNGCNYTNACNTCNYTNAAR GAYGTNGGNTTYATHAAYTAYTTYGGNATGCARMGNTTYGGNACNACNGCNATHCCNACN CAYMGNATHGGNMGNGCNYTNYTNAARGGNGAYTGGGARGGNGCNATHGAYYTNATHYTN GCNCCNMGNAAYGAYGTNGCNGCNAARGAYAARTTYCARAARCAYTGGGCNCARACNMGN GAYCCNGCNACNACNYTNGAYYTNACNCCNMGNTAYTGYGGNYTNGARMGNAAYATHYTN GARGCNYTNMGNAARAARTCNAARCCNTTYAAYGCNYTNGARMGNYTNCCNMGNAAYACN MGNYTNYTNTAYYTNCAYAGYTAYCARTCNYTNGTNTGGAAYAARATGGCNTCNMGNMGN YTNGCNGARYTNGGNMGNGARGTNGTNCCNGGNGAYYTNGTNATGGGNMGNCARYTNTGG GCNGAYAARGGNCARAGYGCN------CCNGTNCCNGTNGTNGTNACNGAYGARAAYAAR GAYAARTAYGCNGTNACNGAYGTNGTNYTNCCNYTNCCNGGNTAYGAYGTNATHTAYCCN CAYAAYCARGTNGGNGAYTGGTAYAARGARYTNYTNTCNTCNGAYGGNYTNGAYATHGAY AAYATGAARMGNAAYCARAARGAYTAYTCNYTNTCNGGNGCNTAYMGNCAYYTNGTNGTN ATHCCNGARGAYGTNTCNTGGGCNCAYCAYMGNTAYGAYGAYTAYACNAARCCNYTNACN YTNAGYGAYTTYGAYYTNATHTTYGGNGARCCNYTN---CCN---TAYTCNGAYGARGGN GCNCAYMGNGCNGTNGTNYTNCAYATGTCNYTNCCNTCNTCNTGYTAYGCNACNATGGCN YTNMGNGARGCNATGMGNATHGAYACNTCNTCNGTNCAYCARGCNTCNYTNAAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARATGGCNGAYGARYTNCCNYTNTTYCCNAAR GCNACNACNATGTAYYTNCAYAGYGGNAAYATGATHAAYTGGAAYMGNYTNAARMGNMGN CCNAAYYTNTCNTCNTCNGARGARYTNTGYGARGTNATHACNGAYACNYTNAAYGCNTAY YTNGARGGNGCNGAYAARACNGARYTNCARTAYGTNACNGARGTNTAYAARGTNAARACN GARAAYGTNGARGTNATHGARGARAGYGARMGNGGNGAYGTNAARATGACNGTNAARATH TTYATHTGYGAYTCNAAYTCNCCNAGYGTNGTNGTNGAYGCNGTNAAYAARGTNYTNAAY GARYTNGGNACNTCNTTYATHGARACNYTNYTNYTNGCNATHAGYCCNAAYGGNGGNGAR GAYCARGAYTCNGARGARCCNGTNAGYTTYTCNACNGTNCARAGYTAYTGGAARGTNATG GARGARYTNGTNGCNAARGAYAARGTNYTNTCNYTNGGNATHTGYGAYTTYGGNAARGAR GGNYTNGARACNYTNTAYAAYTGGGCNCARGTNAARCCNTGYGTNAAYCARGTNAAYYTN GARTCNTGYTGYGTNYTNCCNAARGAYYTNACNGARTAYGCNAARTCNATHAAYGTNCAR YTNYTNACNCAYAAYGAYMGNCCNGTNTTYATHACNAARGARYTNYTNCARGARAARATH YTNAGYGTNACNACNGARMGNGAYAGYGAYGCNTGGGCNCCNGARTGGGTNATHMGNTAY TCNGGNATHYTNAARTGYMGNGGNATHATHAARACNAARGGNTAYATHTTYCAYGCNACN MGNGAYAAYAARAARMGNATHYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGTTYGGNGCNAARMGNCCNYTNTTYGGNGARGARCCNGAYACNCARGGN TGGATGYTNGGNAAYCARGGNAAYGGNGGNTCNGAYMGNAARMGNAARMGNMGNAGYMGN TGGAAYACNGAYAAYGAYGAYAARACNGTNATHCCNGGNATGCCNACNGTNATHCCNTCN AAYYTNTCNGARGCNCARCARMGNCARTAYGTN--------------------------- ------------------------------------------------NNNTCNCCNTCN CCNGARCCNATHTAYAAYAAYGARGGNAARMGNYTNAAYACNMGNGARTAYMGNACNMGN AARAARYTNGARGARGARMGNCAYAARYTNATHCARGARGCNYTNAARYTNAAYACNGAY TTYAARCCNCCNAGYGAYTAYAARCCNCCNGTNGTNMGNGTNAAYGAYAARGTNATGATH CCNCARGARGARCAYCCNGARATHAAYTTYGTNGGNYTNYTNATHGGNCCNMGNGGNAAY ACNYTNAARACNYTNGARAARGAYACNGGNGCNAARATHATHATHMGNGGNAARGGNTCN GTNAARGAYGGNAARATHGGNMGNAARGAYGGNCARCCNYTNCCNGGNGARGAYGARCCN YTNCAYGCNTAYGTNACNGCNAAYAAYCCNGARAAYGTNAARAARGCNGTNGARCARATH AARGARATHATHAARCARGGNATHGARGTNCCNGARGGNCARAAYGAYYTNMGNMGNCAR CARYTNMGNGARYTNGCNYTNYTNAAYGGNACNYTNMGNGARAAYGAYGGNYTNCARAAR YTNMGNCARATHGCNGARAGYCARACNATHGTNACNAAYACNATHATHTGYACNGTNTGY GGNGGNACNGGNCAYATHGCNCARGAYTGYAARCARAARMGNCCNGGNGAYTCNTTYMGN ATGCARCARATGCARAAYCCNGCNGARMGNGCNAARATGGAYAGYGARTAYATGTCNYTN ATGGCNGARYTNGGNGARGGNCCNCCNCCNTCNAARTCNGAYTCNCAR------GGNCCN GGNAAYTTYGGNCARAAYCARTCNCCNTTYAAYMGNCCNYTNYTNACNAAYCCNCCNCCN AAYCCNATGGCNGTNAAYCCNCCNTGGCARATG---CCNGGNAAYMGNCCNCCNATGACN GGNCCNGTNCCNCCNCCNCCNTCNAGYTCNGGNCCNCCNYTNYTNAGYMGNCCNCCNATG GGNATGCARTCNACNGCNCCNCARATHAAYCCNATGGGNMGNYTNCCNATGCCNYTNATG AAYAAY------AAYCCNCCNGGNGGNATGCARCARGGNCCNCCNCCNAAYATGYTNCCN CCNCCNCCNGGNCARCARATGGGNAAYATGCARCARYTNCCNCCNCCNCCN--------- ------------------------CARCARCARCARCARCAYCARTCNYTNMGNCCNTGG CARCARCCNACN---AGYCARACNCARCCNATGATHAAYCARGGNGGN------------ ------------------CCNGCNTCNACNGCNAGYATGGGNATGCCNCCNCCNCCNCCN GGNATGATGAGYGCNCCNCCNCCNCCNCCNGTNAGYACNCARGGNCAR---CAR---CAR GCNCCNCCNCCNTGGATGCARCAYCARCCNCCNCARCAYGGNAAYATGCARCARCCNCCN CCNCCNCCNCCNCCNTCNTCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AAYAGYTTYTGGGGNACNMGNCARTCNCCNAGYCARGCNAAR TCNTCNACNMGNYTNATGTGGAARTCNCARTAYGTNCCNTTYGAYGGNATHCCNTTYATH AAYTCNGGNAGYMGNGCNGTNGTNATGGARTGYCARTAYGGNCCNMGNMGNAARGGNGCN GGNAARMGNAGYCAYTGYCCNACNGARGGNAAYTTYMGNCARACNTGYCCNGCNMGNATH TAYGTNAARAARGTNMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNGARATGGAYGARAAYGAYAAYAGYTTYCCNTGGGGNYTNATHCAY CAYAAYGARYTNGCNACNATGYTNAAYCAYGGNYTNGGNAARACNATGGTNATHGAYAGY MGNTCNTTYYTNGARTAYAAYACNAGYAAYATHCARCARTCNGTNAAYGTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATHYTNCARMGNTTYGTNYTNACNCAYAAYYTNACNTTY GCNYTNCCNAAYAARCCNATHCAYGTNTTYGGNTCNAAYTAYATHGTNAARCCNGGNCAR ATHTTYACNCCNGAYMGNYTNYTNCCNYTNGTNAGYGGNGARACNCARTAYAAYATHYTN TGGAGYCAYAGYATHTAYAAYAARTCNACNTTYCAYGCNATHYTNCCNCAYGAYACNCAY TAYTTYTCNATHATHMGNGARCCNTTYCARCARTTYATHTCNTCNTTYGARTAYTAYGGN GTNTCNAARGCNATHGCNAARATGAAYATHAGYYTNGAYGTNATHTCNAAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TTYAARGCNGARGGNATHAAYGTNACNGCNGARCCNGGNAAYAGYYTNCAYAGYMGNTTY TTYYTNYTNTTYCAYCARCCNATGMGNGTNATGAAYTGGYTNGTNTTYYTNACNTGYYTN GTNATGGCNTAYCARGCNTTYMGNYTNGTNCARAGYTCNGARTGGAGYCAYATHATHTCN YTNGCNYTNYTNATGTTYTGYAAYTTYTAYACNYTNTTYAARYTNATGMGNGAYTGGTTY ATHATGGGNAARGTNTAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARAGYCCNMGNGARMGNCAYAARGARYTNATGACNCARGCNCARGARGCNGCNGAR AARGCNGTNMGNYTNAAYCCNCARTCNGGNGAYGCNCAYMGNTGGGCNGCNATHATHYTN GGNAGYGTNACNCARTAYATGCCNACNCARGARCARATHAARAGYGCNTAYATHATHAAR GAYCAYATHGARACNGCNATHMGNTAYAARCCNGARGAYTCNYTNYTNTAYCAYATGATG GGNMGNTGGTGYTAYTCNGTNTAYATGYTNTCNTGGATGGARMGNAARGTNGCNTCNGCN YTNTTYGCNACNCCNCCNACNGCNACNYTNGARGARGCNATGAAYAAYTTYCARAARGCN GARCAYYTNAAYCCNYTNTCNTCNATHTCNAAYCARYTNTAYYTNGCNAARTCNTTYATH GCNAARGGNGAYTAYTCNGCNGCNGTNGAYTAYYTNAARTCNGGNGGNGARYTNAARTGY AARAAYACNGAYGAYMGNACNGCNAARAAYGARATHGARAARYTNTAYMGNCARTAYAAR TCNTAYGGNMGNGTNAARTAYACNGAYCARGARGAYYTNTCNYTNATHGARTAYGTNGTN MGNTAYGGNACNTAYAARGGNMGNGAYTTYTGGAARAARGCNGARCAYTGYAARYTNACN ACNCAYACNTGYGARAGYATGMGNTCNMGNTTYYTNAARACNATHYTNCCNCAYATHMGN TCNTAYMGNATHCCNAARGCNTGGAARMGNAARYTNGGNYTN------------------ ---CCNGTNGCNGTNCARGARGARGARGCN------ATHTAYGAYGARGGNGTNACN--- GAR---AGYYTNTCNGAYTAYCCNTGGTTYCAYGGNAGYATHGAYMGNAARGARGGNGAR AARMGNYTNYTNTCNGTNGGNCARGTNGGNACNTTYYTNATHMGNACNAGYACN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TCNAGY GTNAARTCNGTNCCNTAYATGACNTCNCCNGGNCCNGCNGARTCNGAYAAYACNACNTTY TCNCAYTAYMGNCAYMGNTTYTCNATGCCNTCNACNGARTGGCCNATGACNYTNGAYMGN ATGTGGTAYAGYYTNGAYATHGGNCCNGTNCAYYTNATHAGYTAYTCNACNGARGTNYTN ACNGGNGAYGARAARTAYGCNGAYACNCARAAYAAYTGGYTNATHAARGAYYTNAARGTN GCNAAYGARAAYMGNGARMGNACNCCNTGGATHGTNGCNTTYGGNCAYMGNCCNATGTAY TGYTCNACNTCNGAYGCNTCNYTNGCNTGYAARAARCARAARTCNAARAARGCNCARAAR YTNGARGAYGTNATGTAYCAYTAYGGNGTNGAYGTNATHATHTCNTCNACNGGNCARGGN AAYGARATHTCNTAYCCNATGTAYAARGGNGTNAARGTNGGNGAYGAYCAYGCNCAYCCN YTNGCNCCNATHCAYATHAAYGTNGCNTCNGCNTCNCCNTGGAARGCNGARCAYAAYTCN ACNGARGAR------GAYTGGGTNTAYTAYTCNGAYGAYNNNAGYACNGCNYTNNNNTTY GGNMGNATHCARGTNGTNAAYMGNAGYYTNYTNMGNTTYGARGTNGTNTCNTTYGARGGN TAYAARGTNYTNGARTCNYTNGARGTNTTYCARCCNCAYCAYGGNYTNTTYTCNAARGAY GAYYTNCCNGCNAAYATHTCNGCNCARATHGAYAARCARATHGARGTNTCNGGNGGNAAY CCNNNNGTNATHAAYATHGARGARACNGGNAAYAGYGAYATHACNAARAARATHGARGAR ATHYTNCAYGGNGAYAAYMGNAAYACNATHGTNATHGGNGGNAGYGTNGCNGGNGTNGTN YTNTTYYTNYTNGTNGCNGTNYTNYTNYTNMGNMGNGTNATGMGNGGNMGNMGNMGNCAR TCNGCNMGNMGNTGGGARAAYATGGAYATHAAYTAYGGNAARMGNTAYTAYAAYAARGCN CCNGAYAARGARGAY---GAYAAYGAYTTYGARATHGAYATGACNGARACNACNGCNTCN MGNAARYTNYTNTCNGAYGAY--------------------------------------- ------------------------------------------------------------ ------------------------GAYGAYYTNYTNGTNCARATHCAYTCNYTNCARGAR GARAAYCARAARYTNAAYGARGAYYTNTCNMGNATGAARCARAARTAYGAYGAYAARAAY CARMGNATHTCNCARYTNAARAGYGAYYTNGARMGNCARAARAARAARGARGCNGARGAR ACNGCNGTNATHGARAARGCNGTNATGCARGTNGARGARAAYYTNGTNAGYACNACNCAR MGNGCNGTNCARGCNGARGCNACNGTNACNAARYTNAARCARGARGTNAARGCNYTNCAR ACNCARGTNMGNTGYYTNACNGCNGARAAYGARGCNTAYMGNAGYGGNGAYGGNGGNATG TCNGAYATHMGNGARMGNACNAARTAYACNTCNCARCARYTNAARGTNGGNGCNGAYACN GCNGARAARAGYYTNAARGARYTNYTNCARGGNGTNGARCARATGMGNYTNYTNTCNCAR GTNYTNGCNAGYTGGGARAARGTNACNGARGTNACNCCNGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYCARAARAAYCCNGAYGTNTAYTGYATHMGNGCN YTNGTNMGNAGYTGYMGNAAYGARGAYAARYTNGCNYTNAARGAYYTNGAYTAYGCNYTN TCNTTYAGYCCNAARCAYGTNAGYTGYYTNGTNGTNMGNGGNGCNATHACNMGNCCNTGG ---------------------------------------------------GCNGARAAR YTNAAYCCNGAYTCNCARTCNTAYTTYAAYGTNGAYAGYTTYAAYCAYCCNTGYGTNCAR GAYTTYTAYGAYMGNATGYTNTTYACNYTNYTNGTNCCNCAYACNATGACNGARATHAAY YTNACNCCNGAYAARCCNAGYAARAARCARATHGAYTCNAGYCCNGARCARTTYMGNAGY GARTCNAGYMGNTCNGTNCAYTCNMGNATGGGNTCNCCNACNMGNATGGGNTCNCCNGGN GARMGNYTNGAYCCNTTYMGNTGYGGNACNCCNTCNGTNMGNGARAAYMGNCAYTCNACN MGNMGNMGNYTNGAYTAYGGNGARGCNGTNMGNAARCAYAAYTCNMGNCCNAARACNGCN TCNGARTAYATGGCNGTNYTNGARAARCARMGNMGNATHGAYGCNGCNTCNATHGCNMGN GCNCARTCNGCNACNACNTCNTCNTCNTCNCCNTAYGGNGARTCNGCNGGNCAYAGYGTN GGNCARTCNTCNACNACNAAYTCNAGYGGNMGNACNACNAARACNMGNAGYACNAARGCN TTYGTNTTYGARACNCCNGCNAAYTAYTCNATHCCNGTNTTYCARCCNATGAAYATHGCN GAYGCNCCNMGNATGTAYTAYMGNCCNTGGMGNGGNGAYAARYTNCCNATHGGNGAYGTN CCNCAYCCNGARCCNGCNCCNGCNTTYTAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CARMGNCARAARGGNGARTTYCCNGTNCARGAYYTNAARACNAARGARGGNGGNYTN YTNCARGTNTGYATGGARGGNATHGGNYTNYTN------ATGGGNCARCAYCCNTCNMGN CARGAYATHYTNCAYAAYGARGTNAGYGAYATGAARATGMGNAAYTGGYTNTGYGCNAAY GTNGCNATGMGNGAYTCNTCNAARGCNYTNGCNGTNTGYGTNCAYMGNMGNATHTCNCAR ATHCAYAARGARATGYTNYTNGCNGTNGGNMGNGGNCCNCARTGYACNAGYAAYTGYACN TGGAGYMGNACNGAYTGGTGYTCNATHTGYGARMGNTGGTCNMGNGARATHATHGCNATH TGYGARCCNGAYTAYMGNCCNMGNATHAAYTGGTCNMGNYTNAAYTCNTCNCARTGGCCN CAYAAYCCNTAYGARGTNGCNMGNGCNYTNATHCCNAARGCNCAYMGNYTNTAYTAYAAR TGYTCNGARTTYCAYGARGAYTTYMGNTTYAGYYTNAGYTTYATHGARAAYTGYACNGAR ATHCCNGTNTCNMGNTCNYTNTGYGARAARGCNTGGCARTTYMGNAGYMGNYTNAARMGN AARAAYAGYACNATGMGNATGGGNGGNGGNGARYTNGARGAYGGNGTNTCNACNATGATH TCNYTNGTNTCNATHCCNGCNYTNGGNGGNAAYGGNGGNACNGTNGARAARYTNMGNACN YTNACNGAYGCNGAYGAYCARGARAAYGGNAGYTGYTGYGTNATG--------------- ------------------YTNAAYYTNCCNGTNMGNACNTTYGCNTCNGGNTCNACNAAY AGYATGCARGGNGCNGCNTTYYTNAGYGCNAARAARGAYGCNATHGTNGCNGAYATHGGN GGNACNACNTGYGAYGTNGGNATHYTNAARAGYGGNTTYCCNMGNGARGCNTCNACNMGN ATHACNGTNGCNGGNGTNAARACNAAYTTYMGNATGCCNGAYGTNATHAGYGTNGGNYTN GGNGGNGGNTCNTAYGTNACNGARACNAARGGNGARGAYGAYGARGTNATHGGNGTNGAR GTNGGNCCNTGYAGYGCNGGNTAYAAYYTNAARAAYGARGCNTTYGTNTAYAAYGAYTCN CARAGYAAYGARGGNMGNACNYTNACNGCNACNGAYATHGCNGTNGCNTCNGGNYTNTGY GAYYTNGGNTTYAARGAYAARGTNGCNCAYYTNGAYAARGAYTTYGTNAAYAAYGCNYTN GAYAARATHCAYACNATGYTNGARAAYYTNGTNGAYGCNATHAARYTNAARCARGARGAY GTNCCNGTNATHGTNGTNGGNGGNGGNAGYGTNYTNATHGAYACNAARMGNCCNTTYMGN GGNGCNTCNGARYTNATHATHCCNCCNCAYTTYGGNGTNGCNAAYGCNATHGGNGCNGCN YTNAGYAARGTNTCNGCNAGYGTNGAYACNATGGTNAAYYTNYTNAAYYTNATHAAYGTN CARCARATGAAYYTNAARATHAARGARGCNAARGARTGYYTNTCNMGNTCNGAY---MGN GAYATHAARTGYGCNGTNGAYGAYGCNAARAAYYTNTTYTAYAARMGNGCNMGNGARCAR GCNATGGARACNGTNTGYGARCARGCNAARTCNGARGTNATHMGNYTNGGNGCNAAYGAR AAYGAYGTNGARATHYTNGARAARTCNGAYTCNGTNYTNGCNTAYATHGARGGNMGNGTN ---AAYATHAARGTNAARGTNGTNGGNGARATGAARYTNAARAAYGAYYTNCCNTTYGGN GARGCNAARGARTGGATGAARCCNGARGGNTGGAARCARGTNYTNGARATHAARGAYGAR AARMGNGCNAARCARACNGTNACNTCNACNGGNGCNGCNATH---CCNAAYGCNTCNGAR GARGAYGARGAYGCNACNCARCAYCCNAARGAYCCNTTYATHCARCARGAYTCNGGNGAR TGGATHYTNTCNGARTGGGAYATHGARTGYYTNGCNGTNGGNTCNGGNATHTAYGGNTGY GGNGGNGGNGGNAGYATHCAYYTNGGNMGNATHMGNGCNYTNAARGCNYTNAARAGYGGN AARMGNATHMGNGTNATHMGNCAYGARMGNYTNYTNAARAAYTGYCAYCCNGARAARGAY YTNGTNTTYGTNGTNGGNATGYTNGGNTCNCCNTCNGTNTTYTAYGARACNGGNGCNGCN ACNCARGARTCNGCNGARGCNGTNAARTGYYTNAARGARGTNTAYGAYATHGGNMGNTTY AARGAYGGNAAYYTNGTNAAYAGYMGNGGNGTNAARGTNGARGARGAYGCNGARGGNTGY MGNTTYATHACNCAYTAYAAYCCNTCNGAYAARAARGAR---GAYGARTGYMGNATHATH GGNYTNACNTCNTTYGARTTYGCNGGNTGYAAYGCNATGGARCCNYTNYTNYTNGCNGCN GAYATGGAYYTNCCNYTNATHGAYTCNGAYGGNATGACNMGNGCNTTYCCNTCNYTNGAY ATGTAYATHCCNTTYATGTAYGGNAARYTNCCNTAYCCNYTNTCNATGGTNGGNACNGGN AAYYTNTCNGARMGNGGNGTNYTNYTNTAYACNCCNGARAAYAARTTYGCNGARTAYTAY YTNMGNGAYGTNAGYATHAARCAYGGNTGYYTNGGNCAYGTNGCNYTNGCNYTNACNAAR GCNGARGTNGARACNAARGCNGCNCCNGAYGTNGTNAGYAGYGCNTGGMGNYTNGGNGAY GCNGTNYTNMGNGCNMGNYTNGARAARMGNAAYGTNATHGAYGTNATHGTNGARAARGAR AAYGGNAARCAYGTNATHGTNGGNAARATHGTNAAYGTNAARMGNGARACNAGYGGNGGN TTYAAYATHGGNGAYGTNGTNATHCAYGGNGTNGARGARTGGTCNGAYAARAARATHGAR ATHGARTTYCARAAYGARTAYYTNGTNGTNTTYCCNYTNGARGAYGGNTCNMGNGGNACN AGYCARGGNTGYGTNCCNGAYYTNATHTGYATHGTNGAYTCNGARACNGGNGARCCNATH ACNGCNGARGARYTNMGNTAYGGNATGATGGTNGCNGTNGTNYTNYTNCCNTCNTGYGAR YTNYTNMGNMGNCCNGARGCNYTNAARTAYGTNGGNCCNMGNGCNTAYMGNTCNAARGAY GAYGTNTCNTTYGTNCCNTGGAARGARMGNGCNCCNGTNCARCCNGTNCCNCCNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GAYYTNGARAGY AGYGTNGARGARYTNMGNTAYGAYATHYTNAAYCAYCARTGYMGNGTNCARYTNTCNGAY GTNGARGGNATGGCNYTNYTNYTNAGYAAYATHACNAARAAYYTNGCNGAYYTNAARGCN CARTTYCCNGARGTNCARGCNAARATGGCNGARGTNATGAARAAYGARATGACNYTNGTN AARGCNGARGARAAYTTYYTNGTNGARGARCCNTCNAARATHGARAARTCNYTNATGMGN TGYAARAARYTNACNGGNACNYTNTAYACNYTNAARMGNYTNGCNTCNGTNCARGAYCAY CAYCCNCCNCARATHCCNACNATHGCNGCNACNCCNGGNGGNGGNGTNACNGARGARGAY CCNAARAARACNYTNYTNGARAAYATHMGNGCNYTNGTNCCNGAYCAYGAYMGNMGNGTN CARAARYTNGARGCNMGNGARGCNGCNMGNCARMGNATGAARAARATHAAYACNCARAAR GARGCNYTNAARTTYGGNAARAGYYTNGARATGGCNACNAARGGNYTNMGNCCNTCNGGN GCNGCNGGNGAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GGNAARGAYAARTGGTAYAAYYTNAARGCNGGNYTNTTYYTNACN TCNATHACNGGNTGYTCNGTNYTNGCNGGNTTYGGNYTNACNYTNGGNATGGCNAARAAR ACNGAYCARMGNCAYTTYGCNAARGGNYTNGTNGGNTCNAARGARYTNCCNGARAGYGGN GTNGCNYTNGCNACNMGNGCNYTNACNMGNGCNTCNYTNTAYACNGTNTCNGGNTTYGGN GTNTTYTGYTTYGCNGTNTGGAARATGATGGGNGTNCAYAGYATGGCNGARTTYMGNGAR AARGTNGGNAAYGCNYTNCCNMGNYTNAARMGNAARGARAGYACNGGNMGNAAYGARTTY GCNACNATHMGNGAYYTNTTYCARTAYATHATHGAYGARGAYGARAARTCNAARGCNYTN AARAARGARACNGARGARGARGARTGYGARTAYTAYAARCARMGNYTNTAYAGYYTNAAR ATHGTNYTNGARGARTCNCARGARGARYTNMGNYTNYTNAARGARAARTAYMGNGGNATG AGYACNATHGARYTNYTNYTNCARGARACNMGNCARGARAAYATHAARTGGTCNAARCAR GTNAARGCNYTNGARACNGCNATHTCNATHYTNCARAARMGNYTNGAYAARAAYGGNYTN TCNAARAGYGTNAAYATHCARGARGCNGARYTNTTYGTNCCNGGNGCNTCNAARCARACN TTYGAYAAYYTNGCNAARGARACNGCNMGNYTNMGNTCNYTNYTNAARCARGARAAYGGN YTNATHGGNAARAARTCNGCNGAYGARATHGARGAYATGAARTGYGCNYTNGARGAYGCN GARTCNGARAAYAAYGARTTYMGNAAYAARATHAARGAYATGGARATGATHAARYTNAAR YTNGTNAGYGAYTAYGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AAYYTNAAYAARYTNAARMGNTTYYTNAARCAR GCNGARYTNGAYCAYTAYGCNYTNTAYMGNGCNYTNTCNTAYYTNAARAARTGYGGNTGY GGNGCNYTNATHYTNMGNTAYGTNAARYTNGAYGCNGGNTCNGARACNAARTCNGTNYTN ACNGCNYTNGARAGYTTYATHAAYTTYACNAARCARAAYYTN------------------ ------------------------------------------------------------ GAR------AAYGARGGNGARTGYGAYGAYGAYCARTTYTGYGTNAARTAYAARACNATH GTNTGGATHMGNAAYTCNGGNGARATHATGGGNAAYTCNAARGARTCNCAYGTNGTNACN MGNAGYTGYGARTCNAARAARGGNCARAARGARGGNTGYGTNGGNTGGCARAAYAAYGGN GGNGTNACNYTNAARTGYTGGTGYGGNACNGAYAAYTGYAAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TAYCCNACNTGGGGNACNYTNATHCCNTCNTCNGCNYTNATGGGNGCN ATHGCNGGNCCNATGTGGACNTCNCARGGNYTNTAYATHACNTCNTTYGGNGARGAYTAY GCN------------------AARCCNCCNYTNTCNTCNYTNAAYAGYYTNCCNACNACN ACNGGNATGACNTCNAGYGCNGAYGTNAARCCNAAYCARAARYTNYTNGAYCAYYTNACN YTNAARAARTAYTCN---------------------GGNGCNTCNTTYCCNGGNACNAGY AARGTNAARGGNTCNYTNTCNGCNAGYCARGARGCNTAYGCNTGGAARYTNAARAARYTN AARAARACNATHAARGAYTAYATHTTYYTNAAYGGNGCNGTNTGYGAYGARGTNYTNMGN ACNGARGARAARYTNGCNMGNGTNAARGARGARMGNMGNTTYYTNYTNMGNAARYTNYTN CARTTYCARTCNYTNAAYGARTCNATHGGNATGACNGCNAARGCNGAYACNCCNGCNGCN ATGGTNMGNAAYYTNAARGCNACNGCNGGNAAYGARGCNGCNGCNACNGTNGCNCCNACN GGNAARGGNTCNAARGGNGTNAARMGNAARYTN------------------GCNGCNTCN GCNTCNYTNGCNGGNGCNGGNATHAAYGTNGTNACNTCNYTNCCNACNYTNTCNTCNGGN ACNTCNGCNAARAARAARCARACNCARTCNGCNAARGAYATHYTNGAYTCNYTNCARGGN MGNCCNAARAARAGYAARTCNGCNGGNAARAARACNATHCCNCCNYTNATGYTNGAYTCN YTNGGNMGNCCNATGATHCCNATGATGYTNGGNGAYATHACNYTNCAYAGYATGGGNGAR ATHGTNACNGAYMGNYTNAGYTTYCAYTGYCCNGARGCNATHTTYCCNGCNGGNTAYTGY ATHACNMGNGTNTTYATHAGYYTNCAYAARGCNGAYTCNAARTGYYTNTAYACNTGYAAR ATHTCNGARGGNGAYAGYGARCCNYTNTTYGARATHGCNCCNGARGAYAGYTCNGAYATH GTNTTYMGNGCNAGYACNCCNTCNGARTGYCAYAGYYTNYTNYTNMGNGCNGTNAAYAAR TCNMGNGGNGCNGAYATHYTNCCNACNGARACNCAYGGNYTNGAYTTYTTYGGNYTNTCN CAYTCNGTNATHCARAAYYTNATHCARTCNATHCCNGGNGCNMGNAARTGYTCNMGNTAY AARTGGGTNAARTTYGARATHGAYAARACNGARTCNAAYGARAAYTTYGCNGTNGGNCAR AAYGAYCCNACNATHAGYTAYGARGCNTTYYTNAARMGNYTNGTNGCNYTNACNCARGCN MGNCCNGGN---YTNGCNTCNCARATHGARAARTCNACNAAYYTNMGNTCNYTNYTNACN AARAGYAAYGGNATGAARTTYAGYATHGARATHGGNYTNGCNTCNGGNGGNMGNYTNGGN AARATHATHCARACNACNCAYGGNMGNACNGTNACNYTNGAYACNCCNATGTGYACNYTN TTYACNAARGGNGGNAGYGCNCCNTAYYTNAGYYTNAGYATGYTNGARAARGTNAARAAY GTNCCNGARGTNGCNACNATHAGYATHAAYTCNTTYGTNGARCAYGTNGAYAGYATHMGN GARAGYGGNAARMGNYTNGCNGARTTYTCNTCNATGAARAAYAARATHGTNTTYTCNTCN YTNCARGAYGCNAGYGTNCCNYTNCARTCNGGNAARAAYGAYAARTCNGGNGTNGCNGTN TGGGGNAARGGNGGNAARTTYATGYTNGAYCCNAARACNTAYATGCARATGCARCAYGCN YTNCARCCNGAYTGGGTNYTNGCNYTNAGYGAYGGNGAYACNGAYAARGARAGYACNGAR AARMGNGCNGGNAARGCNGTNGAYMGNACNYTNGAYTTYYTNGAYGTNATHGTNTCNGCN TGGAARACNTCNGARGTNYTNAARGGNTCNAGYYTNATHGGNGCNGTNGTNGGNGGNTTY AGYGARAAYCAYMGNCARMGNAGYGCNAARGARACNTCNGCNMGNCCNGTNCAYGGNTTY YTNATHGARGGNTTYCARAARGGNCAYTCNGARGAYATHATHGTNAAYGAYGARCCNTTY CARAARATHYTNACNAARACNYTNAGYCAYYTNCCNGARGGNAARCCNMGNTTYATGGAR ACNCCNTGGTCNCCNYTNCARGTNATHCARGCNTTYAARYTNGGNATHGAYGTNTTYTCN AGYGCNTAYCCNCAYACNYTNTCNGARAARGGNYTNGCNATGACNCAYGAYTTYACNYTN GCNCCNTCNCARCARAARGCNGGNGAYACNGARGTNGGNGGNGGNGGNGAYGCNGCNTCN CCNTCNTCNGTNATGAAYYTNAAYGARAARMGNTTYTTYGAYGAYTTYTCNCCNGTNYTN GARGGNTGYCARTGYTAYACNTGYGCNAAYTTYACNMGNTCNTAYATHCAYCAYYTNYTN AAYACNTCNGARYTNYTNGCNCAYGTNYTNYTNACNATHCAYAAYTTYGARMGNTAYTTY YTNTTYTTYCAYACNYTNMGNGARTCNATGAARAGYGAYAARYTNGCNCARYTNGARACN GTNYTNGCNAARCARGAR------------------------------------------ ---MGNAAYGGNACNATHGCNYTNTGGATHATHTGYAAYATHYTNTGYATHAGYYTNACN CARGCNGCNGCNTTYGTNTGYGCNTCNTGYATGGTNATHGCNYTNGCNACNYTNTGYYTN TTYCARATHCAYACNMGNATHYTNGAYAARATHYTNCCNTCNGCNAARAAR---CCNGTN CARAARGAYGGNGARAGYACNGAYGGNGCNYTNGAYACNGTNCARAAYTTYMGNTAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNTTYAAYTAYGARTCNATGGARCARYTNTCN TAYYTNYTNAARCAYTAYCAYCARATGAARGTNGGNATGGCNGGNMGNAARTCNACNAAR CCNGAYAARTCNYTNGAYGTNGTNCARGGNTCNATGGTNGARGAYYTNGTNGGNYTNYTN CARTCNTTYAARGARAGYTGYTCNAAYATHTAYAARCAYGGNACNGCNCAYGGNACNCAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARAAYAARAARACNAAR---GGNAGYATHAGYTTYGAYGTNATHYTNAARCCN GCNGCN------GCN---GAYTCNCCNAARCCNTCNTCNCCNMGNAAYAGYATGAARAAR GARYTNTCNGARGARAARATHGCNATGAARYTNAARAARGCNGARCARMGNAARAGYYTN ATHGARCARGARMGNATGGARCAYYTNGCNAARGARMGNCARAARGCNATGGAYGTNYTN ACNAARGCNCARTGYGARAGYGARGARTTYTCNAARAARACNGARGARAARYTNAARAAR TCNATGCARACNMGNMGNGARAAYMGNGARACNCARATHMGNGCNYTNCARGARMGNYTN MGNGARCAYTCNGTNAARGTNCAYGARGTNCARAARGCNGGNAAYGARATGGTNAARGAR TTYGARGCNAARGCNGARCARAARYTNACNCARAARATGGGNACNTAYGARGARAAYMGN AARAAYCARYTNTGYAAYATGYTNACNAARYTNCARGARCAYGCNAGYCAYATHAAYGAR GTNTGYATHGCNAGYGARAAYMGNGGNGCNAAYACNGAYGARYTNCARGARCARYTNGTN YTNAARATGGARAAYGCNYTNAARAAYMGNGARGARCARYTNMGNGCNATHCARGAYMGN YTNGCNGARCAYGARAAYMGNATHAARGARGTNCARMGNAARAARGGNATGGTNTCNTCN GGNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATHTGYGCNGCNTGYCARTGYCAYGCNTGYYTN AARCARAGYGGNCAYGTNATHTCNACNTCNYTNCCNYTNCARGTNCCNATHTCNCCNCCN CCNGCNGARYTNAAYYTNTAYCCNCAYATHCAYGGNYTNCCNCCNCARMGNTAYATGTTY GGNYTNCCNTCNCCNYTNYTNCCNTCNATHAARYTNCCNTTYAARYTNGAYYTNGAYGAY CCNGCNAGYATHCAYGAYCAYYTNTAYCAYGCNTAYAGYGAYTGGGAYAAYCCNMGNCCN GGNTCNYTNGCNGCNCARCAYCARCAYCARGCNCAYCCNMGNYTNCCNGGNYTNGCNACN GAYYTNYTNCCNCCNGCNCCNGTNGAYGGNYTNTCN---GCNTTYAGYTTYGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGGGGNTCNATGMGNTCN AARCCNACNGARGCNATGCCNAARCAYTCNYTNTTYGGNACNGCNYTNGARGCNGTNGAY MGNGAYGCNYTNAARGARATHGARGGNMGNTAYATHCCNGARGGNYTNGTNAARGARATH CCNAAYMGNTAYCCNYTNCCNTCNTAYATHAARGARCARATHCCNGGNMGNGAYTGYYTN GARACNTCNMGNAARGTNTGGGCNGCNCARMGNGAYGCNYTNTCNCARGCNGAYAGYCAR YTNMGNGCNAARTCNGARAARGTNYTNGCNTTYAARGCNGAYGARGCNAARCCNGGNTCN GGNCAYGGNAGYGTNMGNTCNAAYMGNCCNACNTGGYTNACNGARAARGAYYTNGARCAY TCNAARGAYATHAAYATHGTNGGNYTNGCNCARCAYGGNAGYTAYAAYMGNGAYAARTAY GGNAARAARCCNCARGTNCAYAAYTAYAGYYTNATHGGNGAYATHYTNGCNCCNAARATG GAYTTYAAYTCNCCNGGNAGYGCNGGNTAYGCNGGNAARGCNGGNTTYGAYGGNACNCAR GCNAAYGTNGTNTAYGGNCCNGGNMGNCARYTNCCNTAYGAYYTNATGGAYAARTCNCAR AAYGCNAARAARMGNAAYCARCCNCARAGYGTNATHGAYYTNCCNCCNAAYATHMGNCAY CARTTYGGNAGYMGNGTNTGYGAYMGNYTNYTNTCNGAYCARGCNATHGTNACNYTNGCN YTNGARMGNCARAARTCNAARATGGGNCCNCCNMGNCCNTCNAARAARCARAAYGTNGAR GGNYTNCCNGTNAAYYTNGAYAAYACNTAYGARAGYYTNGGNCAYACNACNMGNTAYAAY GTNTGYCCNGGNGTNAGYTCNGGNCAYACNATHAGYMGNACNAARGAYGARTTYAAYGAY GARGTNCAYCARMGNMGNGTNCCNAAYCCNGAYGARTAYMGNTAYCARMGNGAYGARYTN AGYACN---TGGTCNGARCAYAAYGTNYTNMGNGARMGNATGAARAARGCNTGG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTN------CCNGCNAAYAAY CCNATHTCNTGGMGNGGNGAYTCNGCNYTNGGNGAYTGYGTNGTNGGNGGNTGGTAYGAY GCNGGNGAYCAYATGAARTTYGGNYTNCCNATGGCNTCNTCNGCNAAYYTNYTNYTNTGG GGNGCNATHAARTTYAARGAYGGNTAYGCNGARGCNGGNCARACNGAYATGATGTAYGAY TCNATHAARTGGGCNACNGAYTAYTTYGCNAAYGCNTGGAAYGARGGNGCNCARGARTTY GTNGCNCARATHGGNGAYGCNAARATHGAYCAYGCNTAYTGGGGNMGNCCNGARAAYATG ACNATGGAYMGNCCNTGYYTNAARATHAGYMGNGAYACNCAYGGNAGYGAYATHGCNGGN GARACNGCNGCNGCNYTNGCNGCNGGNAGYATHYTNTTYAARGAYACNGAYATHGAYTAY TCNAAYATGYTNYTNGCNAARGCNAARAGYYTNTAYGAYTTYGCNAARGCNCAYMGNGGN GTNTTYCAYGGNAGYGARCCNTAYTAYAARTCNTCNGGNGAYMGNGAYGARATGTGYATH GGNGGNGTNTGGYTNTAYMGNGCNACNAARGAYACNCARTAYYTNAAYGAYGCNAARGCN AAYGCNGAYYTNGAYACNGCNTGGGCNYTNAGYTGGGAYGAYAARAARATHTCNTGYCAR ACNYTNYTNTAYGARGARACNAARGAYGGNTCNTAYAARAGYTCNATGGARGCNTTYTTY AAYTCNTGGYTNCCNGGNGGNGGNATGACNTAYACNCCNTGYGGNYTNGCNTGGMGNGAY AARTGGGGNTCNAAYMGNTAYGCNGGNAAYGTNGCNTTYGCNGCNYTNGTNGCNGCNGAR GAYGGNGTNATGACNGAYAARYTNMGNCCNTGGGCNGTNCARCARGTNAAYTAYATGYTN GGNGAYAAYAAYCAYGAYGGNGGNTGYTTYAGYTTYGARATHGGNTAYGGNTCNAARTTY CCNAARTAYCCNCAYCAYMGNGGNGCNTCNGTNAGYGGNCARGTNYTNCARGGNGCNYTN GTNGGNGGNCCNGAYCARAAYGAYAAYTAYAAYGAYAGYCARGAYGAYTAYGTNATGAAY GARGTNGCNACNGAYTAYAAYTCNGGNTTYCARGGNGCNYTNGCNGGNATHGTNCAYYTN CARAARAAYTCNAAYTTYCCNTCNACNACNAAYAARTGYCCNTGY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYAAYGCNCCNTTYAARGAYGTNATG ATHATHYTNACNTTYCARGTNAGYGAYGGNGTNGTNTTYAARTCNGTN---------AAR GARGTNGARGTNTTYYTNACNGAYGCNTGGAGYCAYGGNYTNGAYGCNGAYAARYTNTCN CCNYTNATGAGYMGNATHGCNAAYAAYCCNGTNGTNGTNATGGAYGARGAYCAYAGYGTN GTNGAYAAYTTYTGY--------------------------------------------- ---------------------GAYAGYGCNMGNTAYATHYTNTCNATGGARAGYTCNAGY GAYYTNGARGARTAYATGYTNGARYTNYTNGAYGCNTCNAAYCCNAARGTNMGNTTYTTY YTNCARGARYTNAARGAYMGNTAYGCNGCNAARGGNAARAARACNAAYTAYCARGTNTAY MGNAARGAYATGGCNCCNGARCCNGCNATGGAYAARTCNAARAARAARAAYAARTCNGCN ------------------CCNATHCARCCNAARAGYAAYGCNAAYTCNATGAAYGTNAAY GTNCCNGAYGARTCNTCNGGNTTYAARGTNGAYAARAGYCAYAAYGGNGCNCCNCARAAR AGYAGYGARATHGGNGTNGGNGCNAARAARAARACNAARTAYGTNCCNYTNTAYAGYAAR GARGGNCARGGNAARACNATHGTNAAYATHCCNGGNMGNCAYAARTGYGARTGYCARGCN TCNMGNCAYAARYTNATHAAYAAYTGYACNCARTGYGGNMGNGTNGTNTGYGAYCARGAR GGNGCNGGNCCNTGYATHTTYTGYGGNACNYTNGTNTGYACNCCNGARGARATGGARATH YTNGAYMGNGGNACNAARAARTCNGARAARYTNMGNGARCARYTNATGMGNGARTCNAAR ACNAAYGGNYTNAGYGARGCNGGNCARTCNYTNYTNCCNYTNGGNTTYAAY------AAY CARACNAARGARGAYGARGAYAARGCNYTNAARCAYMGNGAYAARYTNYTNGARTAYGAY MGNACNAGYGTNMGNMGNACNCARGTNATHGAYGAYGARTGYGAYTAYTAYGCNACNGAY TCNAAYMGNTGGYTNAARAARGARGAYMGNGARAARYTNMGNAARMGNGARGARGARYTN MGNGARTCNMGNCAYGGNTCNMGNMGNAAYMGNAARATGACNTTYGAYATHGCNGGNMGN AAYGTNAARGTNTTYGARGARGARGAYGARTCNMGNAARGAYGTNTAYAAYMGNGARGAY GCNGTNATHCARGARGTNCAYTAYGGNAARTCNTTYCCNAAYAGYYTNAAYACN---AAY YTNGTNAAYCCNYTNTTYGAYTTYGARCCNCCNACNTTYATGGARTCNGARCCNTCNAAR TGGGGNCCNGARATGTTYMGNCCNGCNTCNGARGAYCAYYTNGAYCCNCARGTNTCNTCN MGNMGNATHCARGAYMGNGARYTNCARGARATGAGYGAYGARGGNATGTGYYTNAGYATG CAYCARCCNTGGGCNTCNYTNYTNGTNTGYGGNATHAARATGCAYGARGGNMGNACNTGG TAYACNCCNCAYMGNGGNMGNYTNTGGATHGCNTCNACNGCNAARGCNGCNGAYGARGAY GARATHMGNGAYYTNGARCARTTYTAYAARCAYTTYTAYGCNGAYATGAARATGAARTTY CCNAARGAYTAYCCNACNGGNTGYYTNYTNGGNTGYGTNAAYGTNGAYGARTGYYTNGAY CARGGNCARTAYMGNGARAARTTYCCNGARGGNGARTCNCAYTCNCCNTAYGTNTTYGTN TGYACNAAYCCNTCNAARYTNYTNGTNAAYTTYCCNATGAARGGNAARCAYAARATHTAY AARYTNGAYTCNCAYGTNCAYCARGCNGCNAARAARGGNYTNMGNTGGGARAARTCNTGY AARATHTGGTCNAAYTCNGAYGGNTCNATHTAYAGYGCNACNTTYTCNGCNCCNGCNCCN TCNAARAAYTTYYTNCARATHTAYATHAAYGCNACNCARGTNATHYTNMGNATHTGGAAR ATHYTNCCNCCNACNMGNGCNGAYTCNAAYCARGCNCCNACNCARATHGTNTGYACNTAY TCNGARTTYYTNGAYGAYGARAARATGMGNGGNGARATHGAYMGNAAYATGGGNCCNMGN GARYTNGCNTTYGTNGAYGGNGTNGTNAAYAARCAYYTNGAYTGGYTNAAYAARYTNCCN MGNAARGTNYTNYTNMGNATHTGYTTYTTYYTNGAYYTNGTNTCNATHGCNMGNYTNGGN CARGTNAAYAARYTNTTYMGNGARYTNTGYAGYTGYGAYGCNYTNTGGTCNAARATHTAY ATGGAYCAYACNAARAARCARGTNTCNCARGARYTNYTNATGYTNGTNGAYCARMGNGGN TGGAARGARGTNTTYTTYATGAAYAARYTNCARYTNCARATGCARATGMGNMGN------ ------------ACNGCNAARGARTCNMGNTTYCAYTAYGGNTTY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNGGNTTYTAYTTYGAYTCNTGYGTNTAYGAYYTNATGTCNACN GGNGAYCARAAYTTYACNYTNTCNGCNYTNTCNTCNYTNCARGAYGTNYTNAARYTNCAY CCNTCNGCNTCNAARACNATHGGNAAYMGNACNTCNYTNGARAAYTAYGAYAARAARTAY GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TAY YTNAGYTTYCCNGCNATHCARMGNCARAARGTNTTYCARYTNMGNAGYGARACNMGNACN YTNYTNGARMGNGTNTCNTGGCARACNYTNCAYATHATHAARTAYTTYTAYATHYTNTAY TTYYTNTTYGGNTCNYTNCCNMGNTCNTGGATHTGYCAYACNTTYGGNATHAGYCARGAY CCNGARTCNTCNCCNYTNGAYTCNYTNGTNGGNYTNATGCARYTNTCNYTNYTNTGGAAR TCNTAYYTNACNTCNTTYGTNTTYTCNTTYGTNYTNACNYTNTCNTTYACNYTNACNMGN ATHTTYCAYACNCARCARYTNGTNYTNCCNGTNACNAGYGTNYTNGARGARTCNAGYGAR MGNMGNYTNTCNGAYGCNYTNGTNTGYTCNTAYTCNCCNYTNYTNCARCAYYTNGCNYTN TAYGAYYTNTGYTGYYTNGGNAARTTYGTNTCNTCNMGNYTNCARGARYTNYTNAGYYTN AGYCARCCNGGNGGNCAYCCNAARATHTGGYTNGCNGTNAGYCARTCNGCNYTNGCNACN ATHCARGAYYTNACNAAYMGNGTNAARGARGARAAYTGGGCNATHATGTCNMGNGTNCCN ATHAGYCAYCAYCAYCARCAYATGAAYGGNGGNGTNAAYGGNCAYTGGAAYCCNGGNTCN GCN---------GGNGAYMGNCARGAYAGYYTNYTNACNCAYMGNGTNACNGAYACNGCN CCNATHCARGCNGTNAAYGARYTNTCNCARYTNAAYCARMGNYTNTCNTCNYTNCCNGTN YTNTCNCAYYTNGTNACNCARAGYCARGAYATHAGYAGYMGNMGNYTNTTYGCNTCNTGY CARAARCARATHTGGGCNGTNGARAGYYTNTCNCAYATHGCNGTNMGNGCNTAYACNGAR GAYMGNTTYGGNGTNGTNCARACNTCNYTNCCNTTYATHTTYACNGCNYTNYTNGAYYTN CAYGARTGYGTNGARAARCAYYTNAARYTNAGYACNTCNCCNMGNMGNGTNAAYGGNTCN CARCARTCNTGYYTNGAYGGNGTNYTNMGNTAYMGNYTNYTNTCNGGNYTNAARGCNGCN YTNTAYMGNATGACNAAYACNTAYAARGCNCAYYTNGARGAYATHAARYTNMGNCCNGAR GARATGAARAARYTNACNCCNTTYATHCARTAYACNYTNTTYCARTGGATHCCNTAYACN YTNTAYGARCCNGGNACNACNTAYTTYTGGGTNCAYTTYGGNYTNGTNATHYTNGGNTTY GTNYTNGCNGTNGTNACNTGYATHGCNCARTGGAARAARCCNGCNCCNTAYGGNAARCAY GAYGTNACNGAYGAYTAYTGGGGNCCNCARATHCCNCARMGNYTNTCNCAYTTYATHTCN GAYGCNATHCCNGGNGTNYTNATGTTYTCNYTNGTNTTYTTYYTNTAYAGYMGNGARGAR AGYGAYAARAARGCNYTNAAYTAYGTNTTYTTYGGNATGTTYYTNGTNCAYACNGTNCAY MGNGGNATHATHCAYCCNYTNATHATGAARTAYAARAGYGCNAARGTNCCNYTNGGNATH TGYYTNGGNGGNGGNYTNCCNAAYGTNYTNTAYCARTGGYTNATHGCNAAYCAYATHGGN GTNGCNAARTAYGAYAGYTCNTAYCCNTAYGAYCCNMGNTTYYTNYTNGGNGTNYTNYTN TAYGTNGCNGGNTTYATHATHAAYMGNTGGGCNGAYTGGAARYTNMGNTCNYTNMGNAAR AARAARGAR------------------AGYAARGGNTAYTAYATHCCNCAYGGNGGNYTN TTYAAYYTNATHTCNTGYCCNAAYTAYTTYGGNGARYTNGTNCARTGGGTNGGNTGGACN ATHGCNACNTGGTCNYTNTCNGGNTTYGTNTGGGCNTGYTTYGGNGCNGCNACNTTYYTN GCNMGNTCNMGNCAYAAYCAYAARTGGTAYCARGARMGNTTYGARGAYTAYCCNCCNAAY MGNAARGCNYTNATHCCNTTYATHTTYTCNGAYAAYGGNTGYAGYCARGARGARTCNYTN TCNMGNACNGCNCARYTNGTNATHAAYGCNMGNGAYYTNTTYTCNGAYGCNAAYACNAAY AARACNGGNYTNACNYTNGAYGARGARATGGCNGCNTTYYTNCCNACNYTNAAYYTNTCN ATGGTNGAYTTYGAYACNGTNACNGTNGCNGAYYTNMGNCAYAARTTYGARMGNAARAAR MGNMGNAARYTNTCNCCNCCNGARMGNMGNAARTTYTCNGARCAYTGYCARCARTTYATG ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AAYATHTGYTAYYTNTGYTCNACNYTNGAYGARCAYMGN CARCAYYTNCARMGNATGMGNATHCCNAARAARGCNCARTCNAARMGNCARCCNATHCAR TAYGTNGCNCCNAARCCNAARGTNAARCCNGARCCNAARGARCCNGTNGARCAYTTYACN GARMGNTAYAARGTNGTNYTNTGGACNGGNAAYCAYCCNGARGCNTCNAGYGAYGCNAAY ATHTTYATHAGYYTNAARGGNGAYGARGAYGTNYTNYTNCCNACNCARYTNACNMGNGGN AARTCNAARMGNMGNGTNTTYTCNTGYNNNGGNTCNAARGARACNTTYTAYATHAARGGN CCNCARYTNGGNAAYYTNGARATHYTNTCNATHGARCAYGAYGGNATGGARAARAAYCAY GGNTGGTAYTGY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGCCNYTNTTYAARATHGARACNAAYYTNCCNAARGAYCARATHCCN GARATHTTYYTNCAYGARGCNACNCARYTNATHTCNTCNGARYTNGGNAARCCNGCNTCN TAYGTNAGYATHCARGTNTGYCCNGAYCARGTNATGAGYTTYGGNGGNACNACNGARCCN TGYGCNAAYATHACNYTNAAYTGYATHGGNGTNGTNGGNCCNGAYAARAAYMGNGCNYTN GCNCCNGTNYTNTCNAARTTYGTNGARAARCAYYTNGGNATHAARCARGARMGNTTYTAY ATHAAYATHTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNAARCARATHGARTTYAAYACNATHGCNTCNAGYTTY GCNGGNYTNGTNCARAARYTNGGNGAYYTNCAYAARYTNACNYTNAGYAARGCNGGNAAR ACNTAYACNMGNGAYCARACNCCNACNAAYYTNCCNGCNTCNGGNYTNGCNTCNGGNYTN GCNMGNGCNTGGGARYTNTAYGGNAAYCCNAARGCNGTNATHGTNTTYATHGTNAGYAAY TTYGARMGNAAYGTNYTNGAYCARMGNGCNYTNGARTTYGGNGTNTAYAARMGNAAYCCN CAYATHMGNGTNGTNMGNAARACNYTNGCNGAYGTNCARGAYMGNGGNAGYYTNGAYGGN GARAGYMGNYTNTTYGTNGAYGGNGAYGARGTNGCNGTNYTNTAYYTNMGNGAYGGNTAY ACNGTNGAYAAYTAYCCNTCNCARAARGARTGGGAYGGNMGNYTNAARATGGARYTNTCN MGNGCNATHAARTGYCCNTCNGTNCARTAYCARYTNGCNGGNGCNAARAARATHCARCAR GARYTNGCNMGNCCNGGNGCNYTNGARMGNTTYATHGARGAYCCNGAYGTNGTNCARACN YTNMGNTCNACNTTYGCNAARCARTAYAGYYTNGAYYTNGGNCCNGARGGNGAYAARGCN YTNGARYTNGGNATHGCNTCNCCNGAYAARTTYGTNYTNAARCCNCARMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CARGAR CCNCCNCCNTCNTAYGAYTCNYTNTAYGGNMGNGTNAARGCNGCNAARGCNTCNTCNGAR GGNAAYGTNGAYTTYTTYAARACNTTYYTNATHATHATHYTNTCNACNATHGGNTTYACN ATHATGYTNGGNATHTTYATGGCNGTNCCNGTNTCNATGATHGTNATGGGNGCNATHTAY YTNGAYGAYTGYGARGCNGARMGNATGATHCCNATHTAYYTNATHGTNGCNGGNTGYTTY GGNTGYGCNAARAAYYTNTTYAGYATGGTNCARMGNTGYMGNAARTCNGARGARGARMGN CARGARGAYCARAARAARGTNCAYCCNYTNGARGGNGTNGTNAAYTGYTTYATHTTYGCN TGGTTYATHGCNGGNTGYGTNTTYATHTAYMGNACN---AARGAYGAYTTYCARTCNGAY CAYAARGAYCARGAYGAYTAYTGYGAYTAYACNYTNTAYTGGTAYGCNTTYTGGATHACN ACNTCNGTNTAYATHATHATGGCNGCNAGYTGYYTNTGYGTNTGYTGYATHGGNTGYYTN GCNTCNTGYTTYGTNAARAARACNCAYYTNATHTGYGGNTGYYTNAARAARACNGARAAR TTYYTNGGNGCNTGYATHTCNGGNAARTGGATHGTNGGNCCNCARTTYATHGTNGAYAGY TAYGARGTNGGNATGTGGYTNGARGARGARAAYTAYYTNTTYMGNGTNGARAAYAARGAY CCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARGARGTNACNGAYGAYYTNYTNMGNGTNAAYGAYGAYYTNAAYAAYGTNTTYYTN MGNTAYGARMGNTTYGARMGNTAYMGNACNGGNCARTCNGGNCARGCNACNACNCCNTCN TCNGARTCNGCNCCNCCNAGYTCNYTNCCNCCNGCNTAYGAYCARYTNCCNGCNGCNAGY AAYCCNAARGTNGGNAAYYTNATHGAYYTNAGYGARGAYCCNGCNCCNTCNGAYAAYTCN ATHAAYTCNCARYTNGCNGGNYTNACNYTNAAYTCNACNACNGCNATHAAYGCNACNCCN CCNGTNCCNACNMGNGGNGAYGAYGAYTTYGAYATGTTYGCNCARTCNMGNCARTCNTTY GAYCARAAYMGNCARGCNGTNACNTCNACNGCNTAYAAYAAYCARCAYCCNGAYACNTAY AGYGGNGGNYTNGGNCARGCNGTNAGYGCNMGNACNGCNCCNGARAAYTCNACNATGACN GAYGARGAYACN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTN---AARYTNCARGARAARGARACN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARMGNTAYYTNAGYAGYYTNAARTGGAGYATG ACNGTNGCNGGNATHACNGARATHCCNCCNGTNGCNYTNYTNCCNAAYTTYATHGTNCAR AARAARGTNYTNMGNCCNTTYMGNTTYCARACNAGYGGNACNATHATGGCNGGNAARYTN GCNATGGAYMGNGGNTGGGCNATHAAYATHGGNGGNGGNTTYCAYCAYTGYTCNTCNGAY MGNGGNGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNGTNGGNMGNGAYTTYYTNAAYYTNCAYCAYATGAARGCNGAYGAR ATHAARCAYATHYTNTGGACNGCNATGGAYYTNAARTCNMGNATHAARGAYAAYGGNGAR GTNTTYYTNCCNYTNCARGGNAARATHGCNGCNGTNATHTTYCAYAARGARAAYAARATG YTNMGNYTNTCNGCNGARTCNGGNYTNGCNMGNYTNGGNGGNCAYGCNGCNGTNTTYGGN CCNGARTAYYTNCARGGNGAYYTNAARGARMGNYTNCARGARAAYTCNMGNACNYTNGCN AGYATGGCNGAYATHATHGTNGCNMGNGTNTCNGARCARGARGCNYTNMGNACNATHGCN GAYGARTCNGCNGTNCCNGTNATHAAYGGNGGNTCNAAYYTNYTNCAYCCNYTNCARACN YTNGCNATHTTYATGACNATHCARGARCAYTTYGGNTAYYTNMGNGGNTGYCCNGTNTCN TGGATHGGNGAYTCNAAYAGYGTNYTNCAYTCNYTNATGCARGGNTGYGCNAARYTNGGN GTNGAYYTNAGYATHGCNACNCCNGTNGGNTAYGARCCNGAYGCNGAYGTNACNATHGAR GCNATHAARATHGCNGGNAARACNGGNGCNTCNTTYCARATGGGNAAYAAYCCNGTNGAR TCNGTNTAYMGNGCNGAYGTNATHATHACNGAYAGYTGGTTYMGNGGNMGNGGNGTNAAY GAR---------AARAAYYTNAGYGCNTTYAGYGGNTTYCARGTNAAYMGNAARATGYTN AARGARGCNGGNGGNAAYTGGATHTTYATGCAYTGYYTNCCNMGNACNCARGARGARGTN ACNGARAAYYTNTTYTAYGGNGARGARTCNGTNGTNTGGCARYTNGCNGARAAYMGNATG TGGACNATHATGGCNYTNATGYTNTGYCARYTNCARYTNTAYGCNCCNACNATHCCNATG CCNAARTTYGTNMGNGGNATGTCNGARGGNTCNTCNTCNCCNAARMGNGCNMGNYTNGAR TTYGAYGARGGNTCNAARGAYGAYYTNCAYGAYAARTTYAGYAARAAYMGNGAYCARGAY GAYCARGGNAGYTAYAGYAAYCCNAARAARMGNMGNGCNGAYACNGGNGAYGAYGARGAR GAY--------------------------------------------------------- ------------------------------------------------------------ ------------ATGAARGAYATGAARTCNAARAAYGTNGGNGAYGCNGCNMGNMGNGAR CAYACNYTNGTNACNATGYTNYTNGAYCCNGCNATHAAYYTNGTNTTYCARMGNATGTCN AARGARATGGARGARCAYAARGARAARYTNAARCARAARCARAAYGARYTNAAY------ ------------------------------------------------GCNTGGAARTTY ACNCCNGAYAGYCARACNGGNATGMGNYTNATGGGNAARTGYMGNATGYTNYTNCARGAR AAYGARGARYTNGGNAARATGATHTCNTCNGGNMGNACNGCNMGNYTNGARGGNGARATH TCNYTNCAYAARGCNYTNGTNACNGARATGAARAARAAYCARAARGARYTNGAYGARTTY GTNGGNGARYTNGARGARGAYGTNGARGGNATGCARGGNATGATHTTYATGYTNCARCAR CARYTNAARGARGCNMGNGARCARATHACNMGNYTNCARCARGARAAYGARCARYTNMGN ACNYTNCARYTNCCNTCNGARCCNGARCCNGGNGGNAAY--------------------- ------------------------------------------------------------ ---------------------------------------------------------MGN GGNCARGTNCCNGARAARAAYAARYTN---YTNAARYTNCARATHGARMGNGGNGAYGAY ACNCCNMGNACNATGGCNGCNAARGGNMGNYTNACNAARTCNGCNAARAARMGNGGNATG TCNAAYTAYTAYACNATGGGNGAYGARGARMGNGGNYTNGARAARGARTAYTTYAARCCN ATGGARAAYAAYCARGARAAYTAYGTNAARGCNMGNYTNTCNGARGAYGARGARGAYCCN GARACNCCNCCNAGYAGYMGNCCNACNTCNGCNACNGAYGAYGAYGARAARGARGARGAY GARGARACNGGNACNTGGGTNCARTGYTCNATHACNGAYTGYAGYAARTGGMGNTAYGTN CCNGAYATHTCNGAYCCNGCNAGYGTNCCNGAYCAYTGGGAYTGYACNATGAAYTCNGAY AARGARMGNAAYACNTGYGAYTCNCCNGARGTNGAYTAYGAYGARAGYGARCAYATHYTN ACNAARTAYACNYTNGGNTCNYTNGTNTGGGTNAARATGGAYGGNTTYCCNTGGTGGCCN GCNATGGTNGAYACNGAYCCNGAYTAYGAYACNTAYTTYGARYTNCCNACNGCNACNAGY ATGATHCCNCAYATGTAYCAYGTNACNTTYGTNGAYGARCARGTNTCNMGNGCNTGGGTN MGNTCNCAYYTNATHATGCCNTAYGAYCAYMGNTCNGCNCCNATHAAYAARATHAAYCCN AARTCNMGNCCNGGNAARAARGAYYTNCARATHGCNGTNTCNAAYGCNAAYAARGCNYTN AARYTNAAYYTNCARGAYMGNYTNGAYAARTAYAGYTTYYTNAARMGNTTYAGYMGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNGTNGCN ATGGCNTAYGARACNAAYGTNYTNGGNTTYAARGGNCCNMGNAARATGACNATHATHATH CCNGGNATGACNAGYGARCAYACNMGNGTNAAYATHAARCCNCARGGNAGYCAYGAYGGN YTNATHGAYMGNTGGAARMGNAARAAYATGGARAAYYTNYTNGARYTNCAYAAYAARACN CCNGTNTGGAAYGAYGAYACNCARTCNTAYGTNYTNAAYTTYCAYGGNMGNGTNACNCAR GCNTCNGTNAARAAYTTYCARATHGTNCAYGAYAAYGAYGTNGAYTAYATHGTNATGCAR TTYGGNMGNGTNGCNGARGAYGTNTTYACNATGGAYTAYAAYTAYCCNATGTGYGCNYTN CARGCNTTYGGNATHGCNYTNAGYAGYTTYGAYGGNAARYTNGCNTGYGAR--------- ------------------------------------------------------------ ------------------------ACNAAYGGNTCNAAYATHAARMGNTCNYTNCCNGTN GTNGTNAARYTNYTNGCNCAYCCNGAYGCNTTYATHAARMGNGTNGCNGGNGARYTNATH TCNATHCAYGCNCARCARAAYGARGAYGTNTCNYTNYTNAGYATHAAYACNYTNGTNCAR GAYTGYAARGAYGTNAAYCCNGTNGTNMGNGGNGGNAGYTTYMGNACNYTNGGNTCNATG MGNACNAAYGCNGTNTCNGAYGTNYTNAAYACNGCNATHATHGGNGGNYTNGCNGAYAAR AAYGGNTAYGTNMGNMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG GCNTCNTCNAAYAARTGGGARGTNGTNTCNAARAAYAARAAR---CARGGNGARCCNCAR AARATGTCNCCNAARAARMGNGCNGARTTYATHGARAAYATGCCNMGNYTNACNGTNAAR GAYCCNATHGARYTNGAYACNACNYTNTAYGCNGCNTTYATGCCNAARGAYCARCARAAR CARGCNAAYTCNAARGAY---GAYGCNAGYAARCARAAYGGNAGYAARAARACNCCNAGY CARAAYAARAAYAARAARAARGAR---------GAYAARAARCCNAARGTNGTNGAYATH GAYTCNGCNYTNTCNCARYTNGAYTCNAARGARATGAARACNGTNYTNGARAARACNAAR TCNATGTTYCCNAAYCAYCCNACNATHTGGYTNAARGAYYTNGCNTCNTAYYTNAAYAAY AARYTNGARAAYGTNAARGAYGTNGAYCCNGTNTAYAGYGAYMGNTCNGCNGGNTTYCCN YTNGAYGCNGTNCCNTCNTCNATGGCNAARGAYYTNMGNAAYTTYATHAARCARTTYTCN AARGARACNYTNGAYGAYATHTTYATHTTYGGNATHAARACNATGYTNCARGAYGCNGGN MGNGGNACNCCNGTNCAYGGNTTYAARATHTTYYTNCARGTNGTNTCNCARGCNAARGGN TTYACNGGNYTNGAYCAYATHCCNCARTAYYTNGARYTNYTNAARGCNAGYCARAAYAAY CCNCCNAARTGYYTNTCNYTNYTNTGGGCNYTNGGNCARAGYGGNCAYAARAGYTTYCAR TTYGGNYTNAARGTNTGGTTYGARYTNATGYTNCCNGCNYTNGARTAYAARCAYGCNGCN CAYTAYCCNYTNGARTAYYTNGARAARYTNTTYGARMGNCAYCARAGYYTNAAR---AAR ------------AGYCARGGNYTNGTNTCNYTNAGYCARTAYTTYMGNGTNYTNGAYATH TGYTAYGAYCCNAARTAYACNYTNGCNTCNGAYYTNAARACNMGNYTNATHGCNYTNTAY CCNATHATHAARATHATGGCNTAYGGNGARGARCCNTCNCARAAYYTNMGNACNTTYTTY CCNTCNTAYYTNGCNMGNAAYAAYACNAARACNAARCAR---ATGAARGARGARYTNYTN TCNTGYATGACNGARTGYYTNATHATHGAYAARCAYTGYTTYAGYGTNTGGTGYCARATG TAYACNCAYCAYYTNCCNGCNTCNGGNCAYYTNYTNAGYCAYATHAAYAARAAYTGGTCN CARYTNTCNTCNMGNTTYGAYAARAARGTNYTNMGNGARAAYYTNMGNTCNTTYTCNGTN ACNAAYGARGARYTNGARGTNCARACNAAYGGNAARCARGAYGGNYTNAARYTNTCNCAR TCNGCNACNAARGAYYTNATGATGAARYTNACNACNGCNCAYTTYCCNTGGAGYTTYYTN GTNTTYTTYTTYGTNTCNATHTTYGCNGCNATHGTNGTNTAYGAYGTNATGTCNAGYCCN TCNTTYMGNTCNTCNAARACNATGMGNTTYYTNGARCAYTAYGGNGTNYTNGCNYTNYTN GARAARGCNTAYCAYGGNGTNCARCAYGCNGCNAAYYTNTCNACNAAYTGGYTNAARGTN AARTTYCCNATHTTYTAYAAYCARGTNMGNGARACNATHGTNCCNYTNTCNATHACNGTN TGGAAYAGYTCNAARGAYTTYYTNATHAAYGCNGARGTNCAYTCNMGNCCNTAYMGNGAR YTNGCNATGGARAARYTNATHCARTTYTAYTAYTGGGTNTAYGAYYTNTCNCCNGARTTY TGGACNMGNTGYGARGARYTNACNTGGYTNTCNTGGGAYYTNYTNAARGAYTAYTCNTTY MGNATHTGGGTNCARGCNCARTAYTTYGCNGGNGARGCNCAYCAYTGGYTNACNGARCAY GTNYTNACNGGNTCNYTNTCNAARGARGCNATHAARGAYACNGCNYTNTGGGGNGTNGAR CAYYTNCARAAYTGYACNACNYTNTTYGTNTCNTGG------TTYTTYAARGCNTTYYTN CAYTCNYTNMGNGCNACNTGYTTYCARYTNGTNGAYTTYMGNAGYCAYGTNTCNATHMGN GGNTTYYTNGCNGTNGAYGTNGAYGGNGARAAYCARCARCAYTAYGTNYTNTCNGARATH GTNTCNMGNGGNAARGAYAAYGGNATG--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TTYAAR GTNCARGGNMGNTGYTAYTTYATGTAYAARCCNCARGGNMGNAAYMGNACNGCNGGNGTN ACNTCNCARATHGCNYTNGAYAARYTNAARACNGGNYTNMGNGAYAARAAYACNACNTTY GTNTAYCAYTGYCAYAAYCAYTAYTTYTGYCCNGTNGGNTTYGARGAYTCNCCNYTNTAY CARACNGAYGCNTAYAAYGARAAYATHTCNGGNGARTCNYTNGARAAYGCNTGGATHYTN ATHGGNGAYACN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARYTNAARACNYTNGARTGYGTNACNAGYAAYAAYCARAARGCNGTNCARGARYTNGAR GCNGARAARAARGCNYTNGCNTTYAARATHAGYATGCARMGNAARAGYATHGAYYTNTCN GARGAYGARYTNGGNCAYYTNATGAARGARAARTCNCARYTNAAYAARGTNCCNGTNAAY GARATHAAR---GCNYTNAARGTNCARCARYTNGARGCNGARGAYYTNATGTTYMGNAAR CAYYTNGGNATGGARATHMGNAARGTNAARGGNGGNTCNYTNCARGTNGCNTTYTGYCAR ATHGAYCAYAARCARCCNAAYTCNYTNTTYYTNTTYTCNYTNAAYYTNGAYGARAAYMGN CARTAYGTNATHTCNGAYTGYAARCCNCCNGTNTCNGAYYTNGAYGCNATHGTNCAYAAR YTNAAYACNGAYAAYGAYTTYAARACNTTYATHCAYACNATGMGNMGNMGNTTY------ ---AARGCNGGNTCNAGYACNYTNAAYGARTTYCARGARAARTTYGGNGCNGARAAYGTN MGNTTYTAYCARTTYGAYGTNACNGAYCAYGAYAARTTYGARGARGTNATHAAYCARGTN GTNTCNGCNTAYGGNTAYATHGAYATHTTYATHAAYAAYGCNGGNATHATHAAYGARGGN GCNTGGYTNAARNNNATHGAYNNNAAYTAYAARGCNYTNGTNAARGGNACNAARYTNGCN GARGCNGTNATGMGNAARGAYAARGGNGGNAARGGNGGNMGNGTNATHCARATHTGYTCN YTNGCNGGNYTNTGYAGYATNNNNTTYYTNCCNNNNTAYNNNGGNACNAARCAYGCNGTN MGNGCNTTYACNTCNTCNYTNGCNATHCARCCNGAYATHGARGCNCARGGNATGGARTAY GCNATNATHTGYCCNAAYGCNNNNGAYACNGGNATGGTNMGNCARATHGAYNNNACNATG GTNAAYTAYTAYGAYGAYTTYAARGCNAGYGTNGGNAAYGCNYTNATGCCNACNAGYMGN TGYGTNGARGCNYTNYTNCARYTNYTNGAYYTNGARAARATGAAYGGNGCNATHYTNTAY GTNMGNAARMGNMGNTTYAGYGAYGTNYTNGAR---GARATHTAYMGNGGNCCNAARGAY TTYATGGARGCNGGNGTNMGNGGNTTYYTNGTNACNACNATHCCNGAYMGNGARGARCAY GCNATHGAYGARACNGTNAARGTNYTNMGNAARACNTGYGTNAARYTNTAYGGNGGNATH AARCCNYTNAARMGNGARGAYGCNTCNTTYGCNAARGGNTAYGTNATGATHGAYTTYATG GAYCCNGARCARGTNGTNCCNYTNCCNCAYCCNGGNGCNGAYAARGTNGCNGARGARGAR ---------------AARGCNAARGCNGCNGARGARGARAARGAYAARGCNGCNGARGAR ACNGCNAARGTNGAR---------------------------GGNAARGAYAGYGARGCN ATGGARGARGARAAYAARCARGGNCARGARGCNGGNGAYGCNAARGCNGARGGNGARGAR GGNAARGARYTNACNGARGARGARAARGARGCNAARGCNAARGARGARAARGARAARGAR GARAARAARAARAARGARGARGCNAARMGNAARGAYGAY--------------------- ------------------------------------------------------------ ------------MGNAARCCNYTNATGYTNGCNCCNCAYAARTTYCARGCNTTYMGNACN GARYTNMGNAAYATHATGTTYATHAARTCNGAYATHCCNGAYCCNGTNGARGTNGCNACN GCNTGYATGGAYYTNATGCAYCARMGNAARCCNYTNTAYACNGAYTGYATHAAYCARYTN YTNCCNGTNCARGGNGTNTGYGAYAAYGAYTAYAARCARYTNGARATHATGTGYMGNMGN GTNYTNGTNCCNTAYGTNGGNGARCARYTNGARGARCCNCCNAGYTTYGGNGTNYTNYTN GTNAAYAARATGTGYGARCCNGGNGCNGARGTNYTNYTNGARGTNGTNMGNAGYGCNGTN TGGAGYYTNAAYCCNTTYGCNTAYCARTGYTCNGCNTTYGCNGARCCNGAYGTNGTNATH CAYATHGARYTNATHGGNAGYAARATHATHYTNAGYGCNATGCCNCAYTAYATGAARTAY MGNCARTAYAGYCCNTTYGCNGTNCAYGARYTNGGNTCNGGNAARCCNCARGAYGARGAR YTNAARGARAARCAYGARGARCAYAARMGNGARTAYMGNGGNACNMGNGGNGGNMGNMGN AARGAYAARACNYTNMGN------------------------------------------ ---------------------------------GAYAARAARMGNCARGARAARCARGGN GGNGGNGGNGARAARAARGARGGNGGNGARGGNGARGARGARAARGARGGN--------- ------------------------AARGARGGNGARGARGCNGCNGCNGARGGNGCNGAR GGNGGNGARGGNGAYCARATGGARGGNGGNAARGARGARGARGAR--------------- ------------ACNGARGARAAYATHTTYGTNYTNYTNTCNMGNATHTCNGTNAARACN GAYCCNTCNCARCAYYTNCCNAARTAYGCNATHYTNTCNGCNYTNACNAARTAYATHGGN GTNGCNCCNATHCCNATHCARMGNTGYATHMGNACNYTNTAYMGNGTNTTYCAYAAYCCN CAYTGYTTYGARTCNGTNYTNYTNGARCARGCNCCNGCNYTNATHGTNAARAAYYTNATH ATGGAYCARGAYGGNAARTTYCCNTCNATHYTNTTYGGNCARGTNMGNGGNGGNGTNAAY AGYCCNCARATGAGYMGNAARATHAAYTTYGAYGAYYTNYTNTCNTGYTCNCARAAYTCN GARACNCCNTCNGAYTTYGARATGCARATHCARTTYGARTTYGGNGGNGAYGCNTAYAGY AAYATGATHCARCARMGNAGYTTYMGNTCNATGYTNMGNGGNAARGCNGGN--------- ---AGYTTYGGNATGTCNMGNGAYAGYCCNCAYTCNCAYCCNCCNCCNACNCCNGAYGAY MGNATHYTNGCNMGNATHMGNAGYGGNATHAAYYTNATGAARGCNATHACNTCNYTNGCN YTNTCNMGNTAYGGNGAYGGNGARATHCARMGNATHTGGTCNMGNGGNACNGARTCNGAR AARYTNATGTGYGCNATHAGYYTNYTNCAYATGCCNATH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGCARAARYTNATHAAYAARAARGGNGCNAARACNAARAARCARTGGTAYAARCCNCAY YTNGGNGARTCNATGGARCAR---ACNAARAGYTCNMGNAARTCNATHTCNCAYGGNCAY AGYGTNMGNYTNMGNCARYTNAGYCAYGTNYTNTAYGAYAARGTNACNGARATHATHAAY ACNGGNGARYTNTCNCARGAYATHYTNGARMGNCAYGTNGCNATHACNGCNGTNAARATG AGYAARGAYATGAAYACNGTNAAYGTNTTYTGGGAYGCNGAYMGNTCNGAYTGGCARGAR GTNGARGGNYTNGTNACNTCNCAYGGNGGNAARYTNMGNAGYYTNYTNATHTCNTAYCAY GTNYTNGGNMGNGTNCCNCAYYTNGTNTTYGTNAARGAYMGNTCN---ACNGCNCAYGCN AAYCAYYTNGCNMGNYTNTTYGARCARGCNGAYTAYGGNTCNGAYTAYACNCCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGCARMGNTGGATHCCNCCNYTNCCNCARGGNTGGGARGCNMGNTGG GAYCCNGGNCARMGNMGNTAYTTYTTYATHAAYCAYTAYAAYAARAARACNCARTGGGAR GAYCCNMGNTTYCARCARCARCARCARGCNCCNGCNCCNGCNCARCCN------------ ------------CAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AAYMGNMGNAARAAYAARAAY AARMGNAARMGNMGNMGNMGNAARAARAARGGNAAYAARAAYATGTGYAARMGNCAYCAY ATGTAYGTNGAYTTYACNGAYGTNGGNTGGGAYGAYTGGATHATHGCNCCNCCNGGNTAY CCNGCNTAYTAYTGYGAYGGNGARTGYCCNACNCCNYTNCCNYTNTTYACNAARGCNTCN AAYCAYGCNYTNATHCARTCNGCNAGYYTNGARTGGGARCCNYTNGCNCCNYTNGGNCCN CCNGCNGCNTTYCAYGTNGGNTGYYTNATHMGNGGNAAYYTNTAYATHCAYGGNGGNATH TCNAAYATGAARTCNAAYCARCCNTCNAAYCARYTNTAYMGNYTNAAYYTNCAYTCNAAY YTNTGGCARTGYATHMGNGCNGCNGGNAGYCCNACNYTNAGYCAYCAYGCNTGYGTNGTN AGYGARGAYMGNTAYATGATHYTNGTNGGNGGNTGGAAYGGNAARMGNMGNAGYGCNGAY GTNCAYGCNTAYGAYGCNCARGARGAYAARTGGYTNCCNYTNAARCARACNGGNTTYCCN GARGGNGCNGGNYTNAGYTCNCAYACNGCNTCNATGYTNCARAAYGGNGAYATHYTNATH GTNGGNMGNGARGGNAGYYTNMGNYTNCARMGNAARCAYGGNAAYGCNTAYATHYTNAGY GGNAAYGTNYTNTCNGGNCARTTYGTNTAYMGNGARTAYAGYAAYAAYGTNACNTCNMGN TCNGGNCAYTCNGCNAAYGTNATHAGYAAYTCNGTNTTYATHATHGGNGGNMGNAGYGAY AARYTNYTNGARAARGCNACNGGNTTYAARCCNCARACNGARCCNAARTCNYTNATHYTN TCNACNATHYTNCARTCNYTNATHTCNAARCARACNAARCCNATGACNAARYTNCCNTGY GGNMGNAARAAYCAYGTNACNGCNGCNGAYCAYTCNTGYATHYTNGTNCAYGGNGGNGAR ACNTTYGAYGGNMGNAGYMGNGARCCNGTNGGNGARATGTTYGTNATHTCNYTNGCNTCN CCNACNGTNTTYTAYAARYTNAAYACNAGYAGYATHMGNMGNGCNGGNCAYGTNTGYTGY GTNTCNGARGAYGGNATHTAYATHCAYGGNGGNTTYACNGGNCARTCNACNATHAAYTCN GAYGCNTAYCARYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNAGYTAYGTNGCNGARCAR GTNTCNCAYCAYCCNCCNATHTCNGCNTTYTAYTTYGARTGYCCNAGYAARAARGTNAAR ATHAAYGCNTCNATHTAYACNAARTCNAARTTYATGGGNATGTCNATHGGNGTNTCNATG GTNGGNAARGTNMGNYTNMGNYTNGARNNNTTYGAYGARGAYTAYGTNTTYAGYYTNCCN AGYGCNTAYGCNMGNTCNATHYTNACNGTNCCNTGGGTNGARYTNGGNGAYAARGTNTCN YTNACNTGYGAYCARACNGGNTAYCARGCNAAYATHATHTTYCAYACNAARCCNTTYTAY GGNGGNAARYTNCAYCAYATHACNGCNGAYGCNAARAAYACNAARACNGGNGARAGYATH TGYAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CAYCCNYTNCAYGAYGCNYTNGGNATHCAYTCNGARGTN TGYGTNYTNYTNTTYYTNGCNTTYTTYGCNYTNATGGTNTGGTGYTCNGAYMGNMGNCCN TTYGARTTYGCNMGNCAYAARGGNGGNAGYATGTTYGGNYTNATGATGYTNGTNGTNGTN YTNCAYTAYGCNTTYTAYGGNTAYYTNGTNGTNACNGCNAAYCCNGCNAARATHMGNTCN ACNGGNATGCAYCARCCNGTNGGNCCNTGYAAYAARTCNGTNAARGTNCARACNCCNTTY GGNCARGTNYTNAARAARACNCAYTAYYTNTGYYTNAARAAYTAYTCNGARGAYTAYTTY ACNYTNGAYTGYYTNAARAARCCNCCNGCNGAYAARACNGARTGGTAYACNATHTGYGGN ACNCCNTAYACNAAYCAYAARGARTAYATGGTNGTNATHGCNGCNTTYTGYACNGTNGGN YTNTTYTGGTTYTTYCARGCNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TAY ATHCCNACNATHTTYCAYACNGCNTCNATHTGGYTNACNATGGCNYTNGCNATHCARMGN TAYATHTAYGTNTGYCAYTCNTTYAARGCNMGNACNTGGTGYACNGTNMGNAAYGTNGTN TAYGGNACNATHGCNATHTAYGTNYTNTCNTGYYTNAGYCAYGCNACNMGNTTYTTYGAR TCNTAYCCNGTNGARTTYYTNATGCARTCNAARYTNGAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GGNMGNAGYMGNTCNMGNTCNGAR TCNMGNTCNMGNTCNMGNTCNCAYTCNCCNTCN---CCNAARMGNMGNAARTCNTCNGAR AARAGYAARMGNTCNMGNTCNMGNTCNMGNGAYMGNGAYCAYMGNMGNGAYMGNAARCAY MGNTCNCAYMGNTCNMGNTCNAARGARMGNMGNMGNTCNMGNGAYMGN------CAYMGN MGNMGNMGNAGYMGNAGYMGNAGYMGNAGYMGNGAYMGNGAYMGNMGNGAYMGNMGNTAY MGNMGNAGYAGYMGNGAYMGNGAYMGNMGNMGNMGNAGYMGNAGYMGNGAY--------- ------------------------------------MGNMGNGAYAGYCAYAGYCCNAGY CCNCAYGAYGGNAARGTNATHAARTTYGGNAAYAARGTNATHAARCCNGGNGCNAGYTTY GGNMGNCCNACNTCNTCNTCN------TCNAARCCNATHACNTTYAARGARAARATGMGN CARCARYTNATHAARGCNATHGARGARGGNGCNGAYACNAAYGAYGTNYTNGTNAAYAAR GGNGGNTCNACNATHTGYACNCARAGYGCNGGNYTNCARCARACN------GTNCCNAAR CCNAARGGNCCNCCNGTNCCNYTNATGGAYACNATHGTNCCNTCNACNGCNAGYYTNGCN GCNYTNACNGTNACNGCNTCNCARGCNGCNATGCARTCNATGYTNGCNYTNCARAARGAR GCNACNGARAARACNGGNGTNGARATHCCNAARTAYTAYAAYCCNGCNGCNATHAAYCCN ATGAARTAYGCNGARCARGTNCARAARMGNAARYTNYTNTGGTCNAARGCNAARGAYAAR GAYGTNAAYTCNCARTGGCAYGCNACNAGYYTNTCNGGNGAYGCNGAYGAYAARTCNAAR GARAARTTYMGNAARYTNATGGGNATHAARAAYGAYTCNGGNGAYAARGARGGN------ ------------------GARAARGARGARAARCARAARCARYTNTTYGAYCARYTNAAY AARGARTAYGARTTYGCNMGNATGACNACNCAYACNCAYMGNGGNATHGGNYTNGGNTTY GGNTCNTCNTCNGCNTAYCCNCCNCCN------ATGGCNCCNATHCCNGAYGAYAAYCAR GARAARCCNCARTCNGGNGARGAY------GARYTNAGYTCNTTYTCNAAYGGNAAYGTN GCNACNATHACNTTYAGYTCNGAYTCNAGYGAYGARAAYGAY---GARACNTAYCCNGAY YTNACNGGNTAYACNYTNYTNCCNCARGGNCCN------ACNGGNGAYGAYGAYGAYGTN GAYTAYTAYTCNGARAAYGARATHAAYGAYAGYAAYAGYCAYGTNTAYGGNGARGCNYTN ATHGCNGAYGGNGCNAGYATHAGYCCNAGYCAY---------YTNCCNGAYGARGTNATH CARACNGARGGNGTNACNGTNGCNCCNACNGTNTCNGCNTCNAGYGCNTCNCAYCAYCCN GARTTYYTNGCNAARTTYACNGAYGGNAARATHCCNTCNTAYATGCARGTNCCNAAYATH CCNTCNAAYAGYAGYGAYATGYTNTGGAAYAARMGNMGNTCNGAYAARAGY---GTNTCN YTNGAY---ACNGARGAYAAYAARATHATGMGNGCNATGTCNGGNTTYTCNYTNCCNACN GCNAAYGTNCCNGARTGGGCNAARAAYYTNTCNGARGAYCARTGGAAYAAYGTNATHTCN CARCARATHAARCCNTCNCARCARYTNATGTCNGAYATHGCNTGYCARYTNGARCARGAY AAYGARAAYACNGAYTGGGTNGCNGAYTTYTCNGAY------CCNACNGARMGNGTNACN ACNYTNTCNTCNTCNCCNCCNCCNATHMGNGTNGCNGCNTTYAAYATHMGNACNTTYGGN MGNACNYTNGTNTCNAARGAYCAYGTNGTNTCNAGYYTNGTNAARATHTTYCAYMGNTAY GAYATHGTNYTNGTNCARGARGTNMGNGAYTCNTCNYTNACNGCNGTNMGNGAYTTYYTN ACNAGYYTNAARYTNAGYGGNGARGAYTGGGCNTTYGTNGCNAGYCARCCNYTNGGNMGN TCNCAY---TAYAARGARCARTAYGTNTAYTTYTAYAARACNGCNMGNGTNAARATHGTN TCNTCNTAYCARGTNGCNGAYGCN---CARGAYGTNTAYGARMGNGARCCNTTYGCNGTN GARATHGARTAYTTYCCNTCNTCNTCNGCNGCNAAYAAYMGNGTNGTNYTNYTNGGNYTN CAYGCNAARCCNACNGAYGTNGARTCNGARYTNGGNGARTTYTCNAARACNGTNGTNGCN ACNGCNTCNMGNTTYAARGAYTCNCARGGNGTNATHGCNATGGGNGAYYTNAAYGCNGAY TGYAGYTAYYTNAAYGARGARGGNMGNGGNCARYTNGAYYTNTTY---TCNAGYTCNAGY TTYGTNAGYYTNATHGGNGAYGAYGCNGAYACNACNGTNTCNAARAAYACNGAYTGYGCN TAYGAYMGNGTNYTNGTNTAYMGNAAYTGYYTNCAYGTNAGYGGNGCNTCNGTNTTYAAY TTYGARACNTCNYTNAAYYTNGGNTAYGAYGARGCNMGNGARGTNAGYGAYCAYTAYCCN GTNGARTTYYTNYTNTAY---TTYAGYATHAAYYTNTGYGTNGGNCCNACNTAYGAYCAR GAYTGYGCNYTNCAYTTYAAYCCNMGNYTNGAYGAYAAYAARGTNGTNMGNAAYCAYATG GTNGGNGGNGGNTGGGGNCARGARGARTCNGCNGGNGGNTGYCCNTTYAARMGNGGNCAY CAYTTYGARGTNCAYATGAARGCNAAYCAYCAYGGNTAYAARATHACNGTNAAYAAYMGN CAYTTYTGYGAYTAYCARAAYMGNYTNCCNMGNGARAGYATHCARTAYYTNTAYATHGAR GGNGARGTNATHATHACNTAYATHAAYTTYATGGGNGGNCCNTCNNNNCCNNNNCCNCCN CCNCCNGGNGTNCCNAGYTAYCCNCCNGCNGTNCCNAGYTAYCCNCCNGCNCCNAGYTAY CCNTCNGCNCCNGGNTAYCCNCCNGCNCCNTCNTTYCCNTCNGGNCCNTCNTAYCCN--- GGNGCNTTYGGNCCNATHGTNAAYCCNCCNGTNCCNTTYACNACNGCNATHCARGGNGGN GTNGTNCCNGGNAARATHATHTTYATHTCNGGNATHCCNAAYCCNAAYCCNAGYMGNTTY ACNYTNAAYATGCARTGYGGNCCNTAYGAYTCNGGNGAYTTYGCNATGCAYTTYGAYGTN MGNTTYAAYTAYGGNAAYGAYCAYAAYCARGTNATHMGNACNCAYAARCARGCNGGNAAY TAYGGNCCNGARGARAARGGNGTNACNCAYTTYCCNTTYTAYCCNAAYACNCCNTTYCAR ATGATGGTNYTNATHGARCCNGCNTCNTTYAARGTNGCNGTNAAYAAYCARCAYTTYGTN GARTTYTTYCAYMGNATHCARCCNTTYAAYMGNGCNGAYCAYATHAAYATHAGYGGNGAY GTNMGNYTNACNGARGTNMGNTTYCAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARMGNAARATHGGNMGNCARTGYYTNGCNTCNTGGYTNCARAAR AGYGGNAARGCNAARAARGCNAAYGCNGARAGYMGNATGACNCCNCCNACNCCNACNATH AARYTNAAYGARTAYYTNTGYAARYTNCARAGYTAYATGACNGTNATHGCNGARATGTCN GGNCARGTNGAYMGNYTNGAYTCNATHGTNTCNGARGCNGAYAARCCNATGTGGCARCAR GARTGYTGYGCNATGGAYACNYTNAARGAYAARCAYAARGAYYTNAARTCNGTNYTNGAY AARGCNGTNGTNGARCARGCNGARAARAARYTNAAYAARACNMGNCARMGNMGNGTNMGN YTNMGNAARTCNMGNCAYCARCARTTYCARCARATGCARGARGTNGARGARGCNMGNMGN GCNAARGARAARGAYATHAGYGAYTGGCARCARMGNYTNYTNTCNGARATGAARGARGAY YTNATGAARAARAARMGNAARCARGARATGGAYCARACNYTNAGYGARGTNACNAARAAR ATHCAYGAYGCNAAYMGNYTNATHGAYACNATGACNGCNYTNGARAARYTNMGNYTNATH MGNCARGAYGCNGCNAARAARMGNGGNGAYAGYGAYGTNGGNGARTCNMGNGARAGYTTY GARCARAARATHTGYGAYATGACNMGNYTNGTNMGNTCNCARYTNGARGTNTAYMGNGAR GARGARGARCARYTNMGNACNGCNATHAARTCNGARCARGARGARACNAGYAARAARGAR CARCARYTNCARGCNAGYAARGAYGARGARGARCARMGNCARAARGAYGARGARYTNAAR AARATGYTNTTYGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GTNCARTGYCCNTAYAAYCCNTCNCAYATGATHTGYCCNYTNMGNATGCCN TAYCAYYTNCAYMGNTGY---------------------MGNAARAAYCAYCCNAAYGTN ------------------GARATGGCNGTNTGYCCNTAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG AARCARYTNTGYATGAARATHGAYCARCCNATHTTYATHGTNAARGCNAGYGGNCCNCAY ACNAGYAGYTTYTGYATHCCNCCNCARCCNGGNYTNYTNGCNTTYATHCARACNMGNCAY TTYATHGAYYTNCAR------CARTCNGTNTAYATHATHGAYAGYATGGAYCAYATGAAR GTNGCNCARGCNGCNGGNGTNMGNTTYGTNAARAGYAGYAARGCNTTYMGNTAYCCNGAR AARACNYTNACNAGYCARTGYGTNATHCCNCCNGTNCCNGCNATGYTNMGNGCNMGNTCN GARGTNAARTGYCARACNGGNGCNTCNGCNACNGCNTCNYTNCCNYTN---YTNGAYATH TGYGTNGARCAYGGNTGYGGNTTYACNTCNCAYACNCAYCCNAAYGGNTTYGARGARTTY GTNTTYGTNCCNGAYGTNACNAARGTNYTNAAYYTNCARGARAGYTTYGCNAGYYTNGTN ACNCCNACNAAYGARCCNGGNAGYAARATGAARACNGCNCCNMGNATGGAYACNGTNGCN YTNTCNGCNGAYAGYAGYACNACNCCNTGYACNAAYACNAGYACNAGYACNAGYAGYACN AAYAGYMGNCCNMGNYTNCCNGTNTGGATGACNMGNMGNYTNAGYMGNAARTCNACNTCN TCN------GCNTCNGGNGTNGARAGYGAYGARYTNTCNTCNTTYAARTTYGCNAARACN ATHTAYYTNATGAGYGARAARGARYTNAARGARATGGCNYTNCARATHATGAARCARGCN GGNAARGCNYTNYTNAAYMGNGGNMGNAGYGGN---TCNMGNTCNATHCARGCNYTNAAR CARTGYATHMGNACNGCNTCNGGNACNAAYTCNCAYTAYGTNYTNYTNCCNGARGTNCCN GCNGAYACNGCNGARACNAAYGCNGTNATGMGNTTYGAYCARYTNCCNCARTTYTCNCAR ATGACNCCNGCNTCNTGYATHGCNGCNTGYGCNAARYTNTCNATHGARTAYGARACNAAR YTNGARAARCAYATHGAYACNYTNAARGAYCCNAARGTNGARAARTCNTTYGAYGAYGTN TAYYTNCCNYTNGARGARATHGCNGTNCCNYTNAAYACNTCNTGGGCNACNGTNNNNAAY YTNCAYTAYGTNGCNGCNAGYGAYGAYTTYMGNMGNGCNTTYTCNAARGTNCAYCCNCAR GTNGARMGNGTNAARAAYGARMGNTGGGTNAGYCARCCNYTNTAYTAYTCNTTYAARGAR YTNGARGCNAAYAGYGCNAAYYTNACNGARTAYCARAARMGNYTNGTNAAYATGTAYYTN YTNGARGGNAARYTNAAYGGNGTNCAYYTNTCNACNGARGARAGYTCNAARYTNGTNGAY YTNYTNAARYTNATHTCNAARGARAGYCARAAYTTYMGNAAYAARGTNMGNATHTGYACN GAYATHTTYACNCAYAAYGTNACNAAYTTYAAYCAYGTNCAYGARATGCCNTGGTCNTAY YTNGCNMGNATGGCNACNGAYACNACNAAYCCNACNMGNGGNCCNTGGMGNGCNACNYTN CARCCNGAYGTNTAYCARGCNATGATGAARTAYTGYAGYCAYMGNATGACNMGNTGGAAY YTNTGGAAYGCNTAYAAYAAYMGNGCNTCNCAYAAYCAYGCNAGYCARTAYYTNAAYAAY AAYAARYTNATHGARAGYYTNMGNTCNTAYMGNTCNGAYGTNGCNACNATGYTNGGNTAY GAYACNTTYGCNGARATGTCNATGGARACNAARATGGCNGGNTCNGTNGARAAYGTNYTN AGYATGATHGARACNYTNMGNGCNMGNTTYGCNCCNGCNGTNTGGGARGARATGGCNCAR YTNCARGAYTTYGCNACNTCNGARGGNTTYAARCAYTCNYTNGARAAYTGGGAYATHGCN TAYTGGMGNMGNMGNCARMGNGAYCAYYTNTAYAGYGTNAARAARGAYGCNGTNAARGAR TAYTTYCCNATHAAYTCNGTNYTNYTNGGNYTNTTYGAYYTNTGYACNAAYYTNTTYGGN GTNAAYTTYGARGARGTNACNCCNGARGTNGARGTNTGGAAYTCNGAYGTNMGNTTYTTY AAYGTNYTNGAYGGNGARAGYGGNGARCAYATHAGYTCNTTYTAYTTYGAYCCNTTYGAY MGNCCNGGNAARATHTCNTCNGGNTAYATGGAYYTNGGNMGNGAYAAYAGYGARCAYGTN GGNACNTGGCCNTAYTCNTAYYTNTGYYTNMGNATHCCNMGNCCNAARACNTCNTCNGAY CCNGCNYTNATGMGNTTYGARGAYATHGARGTNATGTTYTCNCARTTYGGNCAYGGNYTN CARCARATGYTNACNAARGTNCCNTAYAGYGARATHGCNGGNCARAARAAYATHGARTGG GAYGCNGTNMGNGTNTGYTCNCARTTYATGAARYTNTGGYTNTCNAAYCCNACNGTNGTN AARAGYYTNAGYAGYCAYTAYMGNACNGGNGARACNATHCCNGAYGAYATGYTNTCNAAY ATGYTNAARGTNTCNCARCAYTGGAGYAAYTTYGAYATGATGTAYCARYTNTAYGTNTCN GCNTTYGAYYTNGARATGTAYATGACNAARACNCAYTGGCAYACNGTNTTYAARCARYTN TGGGARAAYTTYATHCCNYTNCCNATGACNGARGARGAYAAYMGNCCNTGYTCNATGYTN CCNATHTTYTGYGAYYTNTAYCCNGCNGCNTAYTAYTCNCAYAARTGGTCNGARATGATH GCNGCNGAYATHTTYTCNGCNTTYCARGARGCNGGNTTYGARAAYCARGARGARATHMGN GTNYTNGGNAARMGNTTYAARGAYACNTAYYTNACNYTNGGNGGNGGNGTNCCNTCNTGY GARGTNTTYMGNCARTTYMGNGGNMGNGAYCCNTCNACNCARGCNYTNCARCCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGNAARGAYGCNGAYCCNGARAAYGARACNGGNAARGTNGCNATHMGN MGNAARATHTGGGAYAAYYTNGARGAYAAYAAYYTNGTNTCNGTNCCNMGNCCNTGYCAY TAYMGNATHCCNAAYTTYGARGGNGCNTCNGAYGCNGCNGAYMGNYTNACNTCNYTNGAR GARTTYAARAARGCNAGYACNATHAARGTNAAYCCNGAYAARGCNCARGARCAYGCNMGN TTYYTNGTNYTNGARGCNGARAARGAYYTNGTNYTNYTNAAYCARAAYCARAARGARYTN ATGGTNCCNACNTCNGARYTNAARTCNGGNYTNYTNAAYMGNGTNGTNCCNCCNGARGGN GCNAAYAARGARGARYTNMGNCAYTGYTGYACNACNCARGGNGTNAARGARAAYAGYAAR GARATHAGYCCNGGNGAYAARGTNAARYTNGAYYTNATHATHGTNGGNAGYGTNGCNGTN TCNMGNAAYGGNTAYMGNATHGGNAARGGNAARGGNTAYGCNGAYYTNGARTAYGCNATG ATGMGNACNATGGGNTCNGCNGAYGCNAAYACNGTNGTNGTNACNACNGTNCAYGAYTCN CARGTNGTNGAYATHGARGAYGARYTNGTNGGNGARCAYGAYATHACNGTNGAYTAYATH YTNACNCCNACNGARGTNATHAARACNAAYTGYAARMGNCCNMGNCCNACNGGNGTNATG TGGAAYCAYYTNGARATHAAYAARTTYTAYCARATHCCNGTNYTNMGNCARYTNMGNAAR AAYGARMGNGAYGAYGGNAARGTNGTNYTNYTNAARGARCARAARGARGARGAYGARGAY CCNGTNGAYGCNATGGARCCNCCNCARCCNMGNMGNTAYGTNMGNTAYTAYAARAAYGAY GGNGGNTTYMGNGGNMGNGGNMGNTAYTAYGGNGGNMGNTAYMGNMGNGGNGGNGGNMGN MGNMGNCARTAYGAYGAYAAYGAYTCNGGNGCNGAYGGNGAYAAYGARGGNGGNCARMGN TCNGGNGGNGGNAAYMGN---MGNGGNGGNGGNCCNCCNMGNAAY--------------- AAYTAYMGNAAYMGNMGNTTYMGNMGNGGNGGN---------AARCCNMGNGCNTCNGAR TCNGARCARAGY---GAYGGNGGNAAYAARGAYAGYGGNGAYGGNGARGAYGGNAAYMGN CCNMGNMGNTAYGAR---AAYMGNMGNMGNTAYAAYCCNAAYAAYGAYMGNMGNMGNMGN TAYGGNGGNCCNMGN------MGNGAYAAYMGN---MGNGAYGAYCAYTCNGGNAGYGAY GGNGARCARAARTAYTCNGCNGAYGAR---GGNGARGGNMGNMGNCCNCARMGNCARAAR TTYMGNACNAAYCCNGAYGCNGTNGTNTAYGTNGGNCARYTNGCNAAYACNYTNMGNGTN AGYCARYTNAARACNGARYTNMGNAGYCAYAAYGTNAAYCCNATGMGNYTNYTNTGGMGN GGNCCNAGYGGNTAYGCNTAYYTNTTYTTYATGGARCCNGAYAAYGCNAARCARGCNATH GAYGCNYTNTCNGGNTTYGARATHAAYGGNMGNGAYGTNAARGTNGARATGGCNAARATG AAYMGNGAYMGNMGNMGNCCNAAYMGNAAYGARMGNGGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TCNTCNTTYGCNCAYTCNGAYGTNTTY AAYGAYYTNGCNGTNCAYACNTTYCCNMGNTCNAARYTNAARTCNGCNCCNTGYGARTTY TGGGARGAYAAYACNGARCCNGTNTAYGARGARGAYAARGCNGARATHATHCARAARGAR YTNAARCARAGYCAYCARACNCARYTNAAYAGYYTNACNAARGARCARGAYACNCARYTN YTNAARATGAARGARGARTTYAAYCARAARATHACNACNGARCARCARMGNYTNGCNTCN GTNYTNGARTCNGARAARGCNACNYTNCARMGNCARCAYGAYMGNGARATGGARGAYATH MGNAARAARTTYTCNGTNAARATGGARTCNYTNAARGAYCARYTNGAYGAYGARGAYGAR GARATGMGNGARAARAARGCNGAYATHGARMGNMGNATGACNTAYGTNGARAARTCNATG AARATHYTNGARTCNCARGARTCNAARYTNGARGARMGNMGNAARAARTTYGCNTCNGAY AARGARMGNYTNGARCARGAYCARGAYGAYGTNYTNGGNTCNAARGTNTCNAGYYTNGGN GTNGCNGARYTNGAYMGNATGMGNGARGARMGNMGNCARYTNTCNCARGARYTNMGNGAR GARCARAAYCARYTNGAYAARGTNAARAAYGARMGNAARACNYTNGARGGNGAYGTNACN MGNYTNAARATGGCNMGNGARCARCARAAYAARAARYTNACNGARATHMGNGARMGNGTN GARACNAARYTNAARGARTTYGARGGNYTNCARGAYMGNTTYTCNAARGARGCNGCNCAR GARGGNCARMGNGCNTGGGCNATHAAYTCN------------AAYYTNTCNACNGCNCCN CCNTCNCCNGCNAAR---ACNAAYAAYCCNYTNCARTCN------TCNTAYCCNCAYGAY ACNAAYACNYTNYTNAGYGARGAYGAYGAYGAYCCNYTNMGNGGNYTNCARMGNATGAGY GAYYTNAARYTNTCNGGNCARTGGTAYAGYAGYYTNTCNATGGARCCNGAYGAYYTNAGY ATHCAYGTNGAYMGNAAYGAYMGNAGYGGNATHMGNGAYTAYYTNCAYAARGARGGNYTN GTNATHGCNMGNGCNAARACNTTYYTNCAYAARCARMGNMGNACNYTNAARCARMGNCAR TCNGCNYTNGCNGCNGCNAARCARGARYTNAAYAARGAYAGYAGYATHYTNCARCARTCN AAYCCNACNCAYGARGCNACNGARGTNYTNGAYAARGTNMGNGAYACNYTNGARACNGAR ATGATHACNATHGAYGCNYTNCARTCNAARTTYGAYACNGAYTCNAARYTNYTNMGNGAR AARGARGARAAYTAYAAYMGNATGGARGGNYTNGCNAARGARAAYGARAGYGARGAYGAR TCNGARTAYAGYCCNTTYGGNMGNCCNTTYCAYGGNGTNAARATHCCNAAYATHGAYYTN AGYGARGAYGARAGYAGYGGNGTNAGYAGYTCNGARGCNAGYYTNGAYGGNTAYTTYCAY GCN---GGNMGNCAYMGNCCNTTYACNAGYACNACNGTNYTNGGNTCNAGYACNGGNCAR GAYGAYYTNTCNMGNGCNYTNYTNMGNATHAAYCAYGAYYTNTCNCAYGTNYTNAGYGTN ATHGGNAARGAYGGNGARTCNATHYTNGGNACN------CCNATHCCNCCNTCNACNCAR CARTAYCARGGNYTNCCNGARGGNGTNCARTGGACNCCNCARCCNCCNAGYCARCCNCCN TCNAARGAYTAYTCNACNATGGTNGCNACNGCNGARCAYTCNYTNGARMGNAARTGGMGN AARTAYTTYGGNGAYMGNMGNCCNCCNTTYACNGCNGTNCCNTCNCAYYTNTCNTCNACN AARGGNTTYGGNTCNTCNTCNAGYYTNTCNMGNGAYCCNAAYTTYTCNMGNCCNGGNTAY TCNTCNATHCARTCNMGNYTNGAYGARCARAARGCNTGGYTNMGNCARCAYTAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GCNAARCARGGNGARAAYTTYGTNYTNACNAAYGARAARATHCAR GCNGTNATHGAYCCNGTNGGNMGNGTNACNTCNYTNAARTGYTTYGAYAAYGARGGNACN YTNYTNTCNAARGARTTYGTNAAYCCNTCNCAYCCNGCNAAYCARTTYGTNATGTAYGAY GAYATHCCNYTNTTYTGGGAYGCNTGGGAYGTNATGGAYTAYCAYATGGARACNMGNACN CCNGTNYTNCARTGYGARAAYGTNTTYTGYACNTCNGGNCCNYTNMGNACNACNYTNAAY TTYACNYTNAARATHAGYGARYTNAGYMGNATHACNCARGARGTNGTNYTNCAYTCNGGN AGYCCNTAYYTNMGNTTYAAYACNACNGTNTCNTGGCAYGARAGYCAYAARATGYTNAAR GCNGARTTYCCNTCNAGYATHCAYGCNATGTCNGCNTCNTAYGAYATHCARAGYGGNTTY TAYAAYMGNCCNAAYCAYTTYAAYACNTCNTGGGAYTCNGCNMGNTTYGARGTNTGYGGN CAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CARYTNTGGCARTGYTTYTAYGCNATHGTN YTNTTYYTNGTNATHYTNATGGGNGTNAARACNMGNATGGTNGARGGNATHTCNGARYTN GARATHGARTCNAGYMGNMGNAARAARGTNCAYTAYTCNYTNTCNYTNATGAARGTNGTN AARTAYMGNCAYACNACNGARGAYGTNCCNGTNGGNGAYYTNTGYGCNGTNTGYYTNGAY GARTTYCAYAAYAAYCARGTNTGYATHAAYYTNCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AGY ATHTCNGTNCARTCNGAYGTNTAYGCNATGGGNGTNGTNATGYTNGARGTNTGYAGYGGN YTNYTNGCNTAYGAYTTYAGYMGNAAYGARAAYAARTTYYTNACNGAYYTNTAYGTNGAY CAYTTY---GCNAARATGAGYGARTCNAGYMGNGTNCARGARTTYCARGAYAARACNCCN CCNGAYMGNATHCARCCNTCNGCNTTYYTNTCNATHYTNAARYTNGCNGCNCARTGYATH MGNGARYTNACNAARGCNMGNCCNAARACNAGYAARYTNGTNAARACNATGGARAARATH TAYGCNACNYTNGARATHYTNAARGARACNTAYGGNAAYAARATHAARGCNAAYAARAAY AAYGTNTCNYTNCARCAYGGNAARGGNGAYTCNGTNACNGGNGCNATHAGYATHGCNAAR AAYTTYCARAAR------GARAAYAAYAARGGNYTNAGYYTNGARGAYMGNATGTCNGTN GARCARTGGYTNGAYTAY------------AGYMGNGARGTNACNTCNATGGARAGYGCN GGNGAYMGNGARMGNATHAGYGTNGTNYTNAARGAYYTNAAYAGYTTYGTNAARGAYMGN GTNTAYTTYGTNGGNACNGCNTGGACNGTNGCNGAYGTNTTYYTNTAYCAYAGYYTNTTY CCNATHTTYGARMGNATHTCNTTYCARGARAARGARCARYTNATHCAYYTNTCNMGNTGG TTYAGYYTNATHCARAGYGAYGAYMGNTCNMGNCARTCNYTNYTNCCNGTNAARTTYYTN MGNACNCCNYTNTAYTCNGGNATHGGNAAYCAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GGNATGGGNMGNCARGCNAARYTNACNATHCCNATHTCNYTNGGNGCNGCNATHGAY AAYGTNAARGAYCAYYTNGGNYTNAAYCAYGTNATHYTNGCNAARGTNGARGAYAARGCN GAYCARATGATHGARTCNGTNGCNGTNTGYGCNGGNTCNGGNTCNAGYGTNYTNAARAGY GCNAARGCNGAYYTNTTYGTNACNGGNGARATGTCNCAYCAYCARGTNYTNGAYGCNGTN CAYGCNGGNACNCAYGTNATHYTNTGYCAYCAYTCNAAYACNGARMGNGGNTTYYTNAAR GAYGTNCARAARMGNYTNGCNAARGTNGTNGGNAARTCNACNTCNATHATHATHTCNGAR ACNGAYMGNGARCCNYTNGARATHGTN------------GARACNYTNTGYATGTAYTGY YTNTCNTGYAARYTNCCNGTNTGYAAYACNTGYTCNACNGAYGGNMGNCAYATGACNCAY GARGTNCARCCNYTNCCNACNYTNTGYAARTCNCARAARAGYGARYTNTCNCARAAYYTN CARTCNYTNTCNGARAARGCNAARTCNGGNACNGARTTYATHCARMGNYTNAARAARATG GCNGAYAGYGTNAGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AARTTYGARMGN YTNATHYTNAARGTNGTNCCNYTNGARCCNGGNGAYTGYYTNGGNTGYAARYTNGTNGGN ACNACNGTNYTNATHGCNAGYGGNGTNATHGTNYTNACNTCNGCNATHGCNGGNAGYAAR MGN---TAYGCNGAYGAYTGGGCNYTNGCNTGYCARGGNCCNGAYTGGGARGAYATGGAR CARACNYTNGCNCARGAYACNAARATHYTNAARGAYTAYTTYGARAGYTGGTAYYTNMGN ATGAAYATGACNAARACNGTNTCNAGYGTNTTYCAYYTNAGYACNAAYATHGCNCAYAAR GARACNAAYGTNCARGTNGAYGGNATHAARYTNCCNTTYGARAGYACNCCNACNTAYYTN GGNGTNACNYTNGAYMGNGCNYTNACNTAYGCNCCNCAYATHGAYMGNYTNTGYCAYAAR YTNMGNMGNMGNGTNGCNATGYTNAARACNYTNGCNGGNAGYACNTGGGGNGCNATHACN AARYTNYTNMGNACNACNGCNYTNGCNYTNATHTAYAGYACNGCNGARTAYTGYGCNCCN GTNTTY------GCNMGNAGYYTNCAYTGYTAYAARATHGAYGTNCARYTNMGNMGNGCN ATGMGNGTNATHTCNGGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYAARAARCCNCCNACNAAYYTNCARGARTTYYTNGAR GCNGARGGNYTNGAYGAYTGGCCNYTNCCNATGAGYYTNGARGGNCCNYTNCAYATHGAR TCNGARGGNYTNTTYATHGGNAAYCARGAYGAYATHGCNGAYATHYTNAAYGARGCNGCN CCNYTNGGNYTNCARATGYTNGARGCNATGGARGAYMGNYTNTCNGCNYTNGARGARAAR ATHAAYTTYTAYGCNGAYCARATHGTNACNAAYGARAARMGNCCNTCNMGNYTNGCNGAR MGNYTNTTYCAYTCNCCNACNAARACNTTYATGACNGAYATGTCNGAYTCNGAYGCNYTN AARTCNCAYMGNAGYTCNAARGGNCAYMGNAGYGTNGAYYTNATGGAYACNATGATGGAR ACNMGNAARAARAGYYTNGAYTAYTAYACNTTYCCNGGNTTYGTNMGNGGNGARTTYATH GARYTNCCNGCNCARYTNGARGCNCCNCCNATHYTNCAYMGNATHACNAAYGCNCARGAY TTYAAYCCNGGNTTYAARAARTTYTGGAARAARYTNTTYYTNTCNGARGCNTCNTCNGCN GTNYTNCARGAYGCNTTYTGGTGGATHTTYYTNGAYAARTTYAAYAARGCNGARGGNTTY GARGARGAYAARGAYTGYATHTTYGAYMGNATHTCNGAYAGYTAYGTNGCNYTNTTYACN AGYATHAAYACNGAYGTNAARGAYAARTTYYTNTCNGTNTAYCCNAGYTGYYTNTCNCAR GCNYTNTAYTAYACNTTYMGNGARGCNTTYCCNGARTCNAARTGGMGNTTYGAYGARACN TTYAARCARCAYYTNGTNAAYYTNGTNTAYGARTGGGTNACNGGNYTNMGNCCNGTNCCN GGNGTNTGGAARGCNTGGAGYGARGARGGNYTNGARGGNAAYCARACNGGNMGNGARAAY GARACNGCNAARAARATGYTNGARGCNGCNGCNYTNAAYAARAARGTNGARYTNAGYYTN GAYATGGAYTCNTTYGCNAARGTNATGGAYAARYTNGGNATGGARACNGCNATHACNCCN CARGGNCAYATGTCNMGNGARGTNACNAARACNAGYAAYMGN------GTNTCNGCNCCN TCNMGNGGNAARTCNCAYTTYTCNAARCARGARTCNCAYCARATHGGNCCNGGNCCNGAY TAYGARMGNGTNAARTTYAAYACNTCNGGNMGNAGYCCNYTNATHGCNCAYTAYYTNCAY ATGMGNCARYTNMGNAGYTAYAARCARCCNGGNATGAARGTNMGNMGNACNGARATHYTN AARYTNCCNCCNGAYGGNCCNACNTAYCARCARTTYATHGCNAAYACNYTNAAYAARGCN GAYACNYTNGARAARGARTAYACNMGNATHTGYGAYCARACNTCNACNGCNATHYTNGAR YTNGARMGNTAYAARMGNGAYTCNAAYMGNGARATHGGNGARYTNAARAARGCNYTNACN AAYATHAARAGYATHCCNGARMGNMGNTCNYTNATGGARAARATHTCNGARTAYAARGAY YTNATGATHAARGARAARCCNYTNATGGAR------------------------------ ------------------------------------------------------------ ------------------------------MGNTAYGTNAARGARGCNAARTGYYTNTGY AAYMGNTGYATHGTNAGYGARGGNATGGGNTGYAARGCNYTNGARGTNGAYCARGTNGTN TAYAARAARATHGGNTGYGAYGGNGARCAYCCNATHTTYGARMGNYTNACNGTNCARGTN AARGTNGGNTGYTAYTGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TGYACNMGNCARMGNMGNCCNGCNGTNAAYAARCCN MGNACNTCNYTNMGNGCNMGNGARTCNGARAARAAYMGNMGNATHGGNAAYGTNCARACN CCNCCNCCNMGNYTNTCNATGGCNGAYGAYTCNGTNYTNCAYTTYAAYAAYGCNGARGAY AGYMGNCARACNGAYAAYTTYTTYCCNGTNAARCCNYTNAARCCNAGYGCNTCNGCNGGN CCNAARGAYGARATHGGNAARYTNCARYTNGARYTNGARAGYTAYYTNCARTTYYTNTGY MGNATHGARCARCARGTNYTNMGNAAYGGNAAYGCNGAYTTYYTNCARAAYAARACNAAR GGNAARGGNAARAAYAGYTTYYTNGCNGARGARGARGAYYTNGAYMGNGTNMGNGTNMGN GCNGGNGARCAYAAYACNMGNTCNGCNMGNAAYYTNTAYAAYYTNTGYCARAARGTNAAR CARYTNCARMGNGAYGTNAGYCARTCNGAYYTNAGYAARCCNACNAARAARAGYCARATH ATGGCNCARYTNAAYGCNACNTAYMGNGGNGCNGTNMGNGCNYTNCARGTNTTYGTNAAY CARYTNCCNTAYCARGAYYTNCARATGGGNYTNCCNTCNACNTAYAAYGARYTNGCNYTN YTNATHMGNCARYTNACNACNYTNATGACNGTNACNMGNCAYGGNTCNAARGTNGARGCN GAYGGNGAYGTNYTNACNYTNYTNGAYCARGTNGAYGAYTTYAAYTCNAARTGGTGYGCN GGNCARCCNYTNCARMGNAARGCNGCNGTNTCNGTNAAYCARAAYGCNGCNGGNCCNAAR GCNTGGGTNAGYGAYACNAARGTNGAYCCNCAYTTYYTNTCNAARAAYGTNACNGARTTY ACNGCN---AARMGNCCNCCNGCNGCNGTNACNAARAARGTNYTNGGNGTNAAYMGNCCN GTNCARAARAARGCNGGNAARGARAAYAARGTNGCNTTYGCNAGYGAR------GGNATG AAYAARGCNTCNYTNGCN---------GGNCARAARACNTTYGGNTTYGTNTCNGTNGAR TCNAARCCNGCNCAYTCNAGYAARTCNGTNATHMGNGAYATHGAYTCNACNAARGGNTAY YTNYTNCCNCCNGARYTNATGGCNAARMGNGARMGNGCNCARMGNGCNGTNGARYTNTCN AAYAARAAYTTYGCNGARTCNACNCAYTCNTCNMGNTCNMGNACNGTNGCNAGYGGNCAR MGNCCNCAYTCNGCNCCNTCNCCNGGNMGNAARAARGARGTNAAYTTYGAYYTNMGNGAR ------CARACNCAYCARCCNTGGATHCCNGCNGGNTGYGCNCCNTGYAAR---CCNACN MGNCCNMGNTCNTCNAGYGCNGARMGNATHCCNTTYTTYGTNAARAAYATGGARGGNCAY AAYATGTGGAAYGARTCNCCNCARMGNMGNAGYGTNACNATGCARGAYMGNCCNMGNGAR GCNGCN---------TAYGGNTAYYTNTCNYTNCCNACNGARGGNCARYTNMGNTCNTGY GAYGTNTCNGAYTCNYTNATHAAYYTNATHGARMGNMGNATHATGCAYMGNATG------ ------------TCNCAYGGNMGNMGNGAYGTNGGNGGNATGMGNCARACNMGNAAYGAY CARATGYTNTAYAGYAGYAAYGARGCNYTNGAYATHACNGAYYTNGAYAARTCNTAYAAY GAYGAYACNAGYYTNAAYACNACNGCNGARGCNGCNAGYATGGTNGAYGCNCCNACNYTN GARAAYATHMGNYTNAARYTNGCNGAYATGGARMGNACNMGNMGNGARATHMGNCARMGN TGGTCNAGYYTNAARTTYGTNGAYACN------------------CAYACNMGNTCNAAR CARGTNAAYGARTGYCCNGARCCNCCNTCNGCNATHGAYTAYTCNATHTCNAARGCNGGN GARAAYAARMGNCAYAAYGAYGARCCNYTNAAYAARGGNTGGTTYGARGARCCNYTNYTN TTYACNAAR---------------------CCNATGTAYACNAGYAARAGYGGNAARGCN GTNACNGCNAARMGNCAYTCNTCNAAYGTNAARTTYMGNCCNCARGTNAARYTNAAYGCN ACNACNYTNGAYMGNATHYTNGARGAYMGNGARMGNTTYGARGARCAYYTNMGNAARMGN TCNCAYCAYCCNACNGGNAARTTYGAYCCNTGGACNYTNATGGARGARATHTCNGARGAR ATHYTNAARGARTGYYTNCARGARGTNTCNGARGARGTNGARAARGTNAGYGARGARATH GCNAAYCARATGTAYAARTCNGARTTYATGGTNACNGGNMGNCCNTCNGARGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARATHYTNGAYAGYAAYYTNTTYGARMGNCCNCAYCAYCARAARYTNCARTCNGTN ACNCCNACNYTNGTNTAYAAYACNGCNMGNTCNTGYMGNTCNACNAARGAYYTNTAYCCN ACNGTNTCNCAYYTNGCNTCNMGNYTNAARYTNAGYATHCCNGARACNYTNGAYGTNYTN GGNGAYGGNGGNTAYGCNGCNYTNCAYYTNTCNGCNATGNNNGGNGAYTTYMGNACNACN TCNTAYYTNYTNGARYTNGGNTCNGAYTGYAAYAARAARTCNGARAGYGGNAAYACNGCN YTNTCNYTNGCNGTNGCNTAYGGNCAYGARTGYGTNGTNCCNYTNYTNYTNAARATGTCN GAYGTNAAYGCNCAYGAYTCNGAYCAYGAYACNCCNYTNATGTTYGCNGCNTGGAAYAAY GAYCCNAARATHGTNTCNGCNYTNGTNCARCAYGGNGCNGAYGTNAAYAARAARAAYAAR TAYGGNAGYAGYTCNATHTGGAAYGCNGTNTAYCARTCNTCNGCNGARTGYGCNYTNATH YTNYTNAGYAAYAAYTGYGCNACNGAYGARTCNTGYGARGGNACNGAYYTNTTYTTYAAY ---GARACNGAYTGYAGYGARAAR------ATHAARAARYTNTAYCCNGGNCARAARMGN TCNYTNYTNTGGGTNGCNGTNGAYMGNYTNCCNGTNAAYGARGGNAGYYTNAARGTNYTN YTNATHYTNYTNGARGCNGGNTAYGAYGTNACNGARGARCAYTGGYTNGGNAAYGGNACN GARMGNGCNTTYATHGGNTTYCCNAAYGAYYTNAARAAYAGYCCNGCNYTNYTNGARYTN YTNCARTTYYTNTAYMGNMGNCCNCARAGYYTNAARGAYYTNTGYMGNAAYTCNYTNMGN AARMGNCARAGYGAYACN------CCNTTYCAYGARTGGYTNCARMGNYTNTGYYTNCCN TCNAGYYTNCARGAYTAYYTNTCNYTNACNTAYYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARMGNGARMGNACNCCNTTYMGNMGN---------ATH GCNGARGGNTGYGCNAAYAARMGNATGGAYATHTTYTTYGTNYTNGAYTCNTCNTCNTCN ATHTAYATHAAYGAYTAYYTNAGYCARCAYMGNATHATHMGNGAYATHGTNAAYCARTTY GAYGTNAGYTTYGAYGCNACNMGNGTNGGNATGYTNACNTTYAGYGAYGAYTAYGGNMGN TCNGTNATHGGNYTNAAYCARTAYAGYAAYAARCARGAYYTNYTNTCNAGYATHACNACN CARAAYYTNCCNTAYATGACNGGNGTNACNAAYACNCAYATHCCNATHMGNTAYGTNMGN GARYTNCCNGAYTTYMGNGARGAYATHACNAARGTNATGGTNGTNYTNACNGAYGGNGGN TCNMGNTCNCARGGNTCNACNTCNMGNGARGCNGARYTNGCNMGNAAYTCNGGNTTYTAY ATGTTYGTNGTNGGNATGGGNCARTAYACNGAYGARMGNGARTGGMGNTCNATHGCNAGY GAYCCNGAYGAYAGYTTYATHTAYAAYGTNACNGGNCCNMGNGCNYTNGAYGARGTNCAR TTYTCNYTNCCNCCNMGNGCNTGYGCNYTNCCNCCNATHATHYTNGGNGGNTCNTGYGAY ATHAGYMGNACNTCNGARATHTCNTTYGTNGCNGGNMGNAGYGGNCARGARGCNGCNCAR AAYTTYYTNGARAGYTTYGGNMGNMGNACNMGNGAYCARMGNGAYYTNYTNMGNGTNAAY TTYTTYATHGAYGGNTGYGCNCCNATHACNGARATGCARYTNYTNAAYGARGARCCNTTY ATHTGYGARMGNTAY------------------------GAYMGNCARGGNAAYGCNATH AAYCCNMGNGGNGCNAGYACNATGTTYAAYGARGCNGTNMGNAAYACNAAYAAYATHATH GTNYTNTTYGCNGAYGARGARACNATGMGNTCNGAYMGNTTYGAYYTNGCNGGNAGYTCN MGNGAYGTNCAR------AAYGGNGCNACNGTNGTNGTNGCNGAYYTNGGNGTNMGNACN TAYMGNGAYTTYGCNCARMGNATHGCNTCNGGNMGNGAYAARTTYATHAGYTTYGTNAGY GGNMGNGGNCARGCN--------------------------------------------- ATGGCNGAYAGYACNAAYCAYCCNGAYYTNYTNTTYGAYAGYCARCCNGARGGNTCNGGN TTYACNAAYGAYGAYTTYGARAARGTNGAYGCNCCNGGNGGNGGNTTYGGNCAYGAYGAY GTNACNGCNGCNGCNGCNGCNGCNTAYGARTAYGAYGTNGAYCARGAYGCNGARATHTCN ACNACNGCNGAYGAYTAYGTNGCNGGNGARGARGARGARGCNGARGTNGARGCNGAYMGN TTYGCNGGNTCNCAYGAYGARCCNGCNTAYCCNTCNCCNGAYCCNYTNATHTCNTGGGGN GAYGAYAAYGAYGTNGAY------------------AAYAAYGAYGAYGARYTNGCNTCN CARGTNCARCCNTCNGCNCCNGTN------CCNGARAAYAAYGARCCNYTNGTNAAYTTY GAYGAYAAYTCN---TCNGGNCAYGAY---TAYTCNGARTCNTTYATGCCNTCNGTNCCN CCNACNAGYGARACNCCNGARCCN---AAYYTNTCNTCNTCNAGYAAYCCNCAYCARACN CARYTNGARGARTTYATHGAYGARCCNAARMGNGARGARGARGGNAARGARAGYAARCAR GARTCNGAYACNACNCCNGARGCN------CCNGCNAARGGNTCNTGGYTNAARGGNGTN GAYCCNMGN---------------------------------GTNATHGAYYTNATHTAY TGGMGNGAYGTNAARACNACNGGNGTNGTNTTYGGNGCNATGYTNGTNGTNYTNYTNTCN YTNGCNATHTTYTCNYTNYTNTCNGTNATGGCNTAYYTNGCNYTNGCNGTNYTNGTNGTN ACNTTYAGYTTYACNGTNTAYAARAARATHATGGGNGCNGTNCARAARTCNAAYGAYGGN CAYCCNTTYAARCARYTNATHGAYATGGAYGTNACNYTNAGYGARGAYAARYTNAARAGY GTNATHCARGCNGTNYTNAARAAYGTNAAYTGYACNGTNAGYGARYTNMGNMGNYTNTTY YTNATHGARGAYATGGTNGAYTCNATHAARTTYGGNYTNYTNYTNTGGGTNYTNACNTAY GTNGGNGCNTGGTTYAAYGGNATGACNYTNATHATHYTNATHGTNATHAGYATHTTYACN YTNCCNAARGTNTAYGARACNTAYAARGTNCARATHGAYAAYTAYATHGGNYTNGCNAAR GGNCAYGTNGAYAAYACNATGGCNATHGTNCARAGYAARYTNCCNTTYYTNAARAARAAR GARAARGCNCAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNYTNYTNGARAARTGGCCNAAYGTNAGYGTNGCN YTNTAYCAYACNCCNGAYYTNMGNGGNGTNYTNAARAARGTNGTNCCNGARMGNTTYAAY GARACNATHGGNYTNACNCAYATGAARGTNTAYYTNATHGAYGAYAGYTTYATHATHAGY GGNGCNAAYYTNAGYAAYGAYTAYTTYACNAAYMGNCARGAYMGNAAYATHYTNTTYAAY GAYTGYCCNCARYTNGCNGAYTTYTTYAAYGAYYTNGTNAARTCNGCNATGTCNTTYTCN YTNCARYTNCAYAGYGAYGAYACNYTNCAYYTNGCNCCNGAYTGGACNGCNCAYCCNTTY YTNGAYTCNGAYGAYGGNTTYAAYTTYAARYTNGCNGCNMGNGARAARATHCARMGNTGY YTNCAR---TCNCAYYTNGTNACNGCNGARGAYGARATGGAY---------------TAY GARGARGTNYTNGAYTAYAGYATHGGNAARCARGAYCCNACNGAYACNGTNATHTAYCCN YTNGTNCARATGGGNCCNTTYGGNGTNCARAAYGAYGARAARGCNACNGTNGARYTNTTY YTNMGNTCNGGNCCNACNGAYYTNATHYTNYTNACNTCNGGNTAYTTYAAYYTNACNGAY CARTAYGCNGAYGTNATHGTNAAYGAYGCNGAYGCNAARTTYAAYATHYTNATGGCNTCN CCNAARGCNAAYGGNTTYYTNGGNGCNAARGGNATHGCNGGNGCNGTNCCNTAYTCNTAY ATHTAYYTNGCNCAYCARTTYTAYAARAARGTNYTNGARGCNGAYCARTGYCARMGNATH CAYATGATGGARTAYGARMGNGARGGNTGG------------------------------ ------------------------------------------------------GTNAAY TCNCARACNAARGARYTNGAYGGNCARYTNACNTCNGCNGARAAYMGNTGYCARYTNYTN GARAARCARYTNGAYTAYATGAARAARYTNGTNGAYGAYTCNGARMGNGAYMGNMGNCAR YTNGTNGARAARACNYTNAARGCNAARCARCARCARCARGAYACNCCNGAYATHMGNYTN CAYYTNGAYMGNYTNAAYGAYYTNGARMGNGAYCARYTNMGNYTNAAYGCNCAYCARAAY YTNACNGARYTNACNCCNATHCCNGTNACNTCNATGGCNAARACNAARAARYTNCCNAAR AARAARGTNAARAARAARCCNGCNACNCCNGTNAGYAGYAAYAAYMGNYTNCCNTGYTCN GARTCNACNMGNCAYTAYMGNYTNAAYYTNGCNGARATHCCNTTYGTNGCNGGNAARTCN ACNACNCCNAGYCAYGCNYTNGGNGCNAAYGTNCARAARGTNYTNGCNATGATGAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNGGNGGNGGNGGNGARGGNGAYGGNGGNAGYGGNTGYGGN GGNGGNCARTCNTCNTCNTCNACNGCNTCNGCNGTNTCNAGYCCNTCNTTYTCNTCNACN GGNCARCARCCNGTNGTNTCNAGYATGATHMGNGAYCCNGAYCARACNACNATGTGYTCN MGNGAYCARGARCCNACNCCNYTNYTNTCNGCNCARTAYGARACNYTNTCNGAYGAYGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNYTNGAYCARCAYGARGGNAAYTCNAAYAARACNAARGCNGARGTNATHGTNCAY ATHGAYTTYAARGGNAARYTNCCNMGNAAYYTNGTNGAYAARTGYATHCCNAAYTCNATH GTNACNTCNTAYTCNCAYTAYATHGARTAYATGAARAARAAYGGNYTNYTNATGTGGMGN TCNCARACNYTNAARMGNGGNMGNCARATHYTNACNYTNACNCARMGNCAYYTNGCNGCN GARGGNGGNGCNACNCCNACNCCN---------CCNCCNCCNCARCCNAARTCNMGNGGN TCNGGNTTYGCNAARTTYGTNGGNYTNGGNYTNCCNYTNGCNACNGGNGGNGTNGTNGGN TAYGCNTGGTAYGAYAARGARTTYMGNAARCARYTNGARGAYAAYGTNCCNTAYGCNAAR GARATGYTNGARAAYGTNYTNCCNTCNGAYAGYACNCARAARGCNCCNCCNAARAARACN GAYTCNYTNCARGTNCCNGCNCCNATHTTYGARTCNAARGAYYTNATHAARAAYGARCAR ACNAARGGNYTNGGNATGTCNATHATHCCNTCNGCNGTNGARACNGGNACNTCNGTNGGN YTNGCNYTNGARAARGAYACNAARAARACNGARGCNGTNTCNMGNGARCARCARYTNMGN AAY---AARGARATGGARGAYAARGCNGAYAAYGCNGCNYTNGARGTNGTNATHGAYAAR YTNYTNGARTCNGGNCARAAYTGGGTNACNGARGCNGCNAARGCNCARYTNGAYGTNGCN AARGCNACNAARAAYCAYAGYTCNYTNYTNAARAARGCNATGGAYGARACNTCNAAYATH YTNGAYAARGAYTCNGARTGGGARTCNGTNACNGTNGCNTAYAARGARMGNGARATHGCN GTNGCNMGNGCNAAYGARYTNGTNGAYGARGCNMGNMGNAGYATHGARAARYTNAARAAR GTNYTNGAYGARGCNAARTCNAAYAARGTNACNATGAARAAYTCNTCNATHTAYCCNGCN TCNAARAARYTNGCNGAYTTYGCNAARGARATGTCNAAYGCNGGNGCNCARGTNMGNCAR GCNGAYGCNGAYGCNAARGTNATGYTNAARTAYAARGAYYTNGTNGAYAARGGNMGNAAR CARTTYCARYTNGARYTNGARTCNYTNGCNCCNGAYGTNAARGTNGGNGGNAARGGNMGN AARYTNACNGARGARGARYTNAAYGCNYTNATHGCNCAYGCNCAYMGNMGNATHGARCAR YTNCARAARCARATHGCNGARCAYYTNGCNATGGARMGNAARMGNYTNAGYYTNGCNYTN GARACNCARAARGARGARAAYAARAGYATHACNCARTCNGCNGTNGTNGAYGARMGNTCN MGNYTNGTNACNGARTTYGARYTNGARAARCARAARATGGARATHGARTTYGCNGCNTGG ATGGARGCNGAYGTNMGNAARCARYTNAGYMGNCARGCNGCNGCNCAYAGYGAYCAYYTN AARGAYGTNYTNGCNGTNCARGARGCNGARATGCARAARGAYTTYGARMGNMGNATGAAY ATHAARYTNYTNGARGARMGNGARAARTTYCARGARGARACNGCNAGYTGGATHTCNMGN YTNAARGGNATHGARGCNGCNGTNGAYGCNMGNGCNGCNAGYGARAARYTNGCNCAYTCN GCNCARGAYYTNTGGYTNGCNTGYATHGCNYTNAAYTCNACNATHCARTTYGGNAAYGAR ---GCNGAYGARTCNYTNATHCCNYTNCARCARCARGTNGARACNATGYTNGCNTCNTCN AAYAARCAYCCNTTYGTNCARACNGTNGCNAAYACNATHCCNCARACNGCNYTNGAYMGN GGNATHTAYACNGARAAYAAYYTNMGNGAYMGNTTYGTNAARGTNTCNCARATHAGYMGN MGNYTNGGNYTNATHCARGARTCNAAYGCNTCNYTNTAYCARTAYYTNGTNTCNTTYATG CAYTCNTTYTTYGCNGTNAAYAGYGTNGCNGCNTAYTCNGARAARGAYTTYGTNTCNYTN AGYGARATGGAYAAYTTYAARYTNGTNGCNAAYGCNCARTAYTGGATGGARAARGGNAAY YTNGAYATGGCNGTNMGNTTYATGAAYCARYTNACNGGNGARTCNMGNMGNGCNGCNGAY GAYTGGATHACNGARGCNAARYTNYTNYTNGARACNMGNCARGCNGCNCARACNATHYTN ACNTTYGCNTCNGCNACNGGNYTNGCNGCNACNTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TCNTCNTCNATG GCNTCNTCNTCNTCNTCNTAYTCNGGNAGYCCNGTNGAYTCNTAYCAYYTNAAYTCNACN ACNAAYTCNAAYGAYACNGAYCAYGAYCCNCARGGNACNAARGCNYTNGCNCAYCARGTN GCNCAYAAYCAYACNTAYAAYACNYTNCCNGGNCAYGTNCCNMGNGARGTNAARAARTAY GCNCCNAARCARCARTCNMGNAARGGNCCNCARTGYMGNGAYGARAARMGNGCNAGYGAR ATGAARATHCCNTTYAGYATHGARGARATHGTNGAYTCNCCNGTNGARACNTTYAAYGAY YTNYTNACNAARCAYAGYYTNAGYGARGARCARYTNACNYTNATHMGNGAYATHMGNMGN MGNGGNAARAAYAARYTNGCNGCNCARAAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGNYTNATHTAYACNYTNGTNYTNTAYGCNATHAGYYTN GTNTTYGCNATHYTNACNGTNYTNAAYYTNGCNTTYATHTTYGTNAARAARGGNCCNAAR ACNGTNYTNTAYAARAARAARMGNGAYGARGARCCNTCNTGYYTNMGNGAYCCNGTNTAY GGNGARCAYGGNTAYYTNCAYYTNGARGAYGTNMGNATHCAYTAYGTNGTNAGYGGNCCN TCNGARAARCCNYTNATGYTNATGYTNCAYGGNTTYCCNGARTCNTGGTAYTCNTGGMGN CAYCARATHAARGARTTYTCNAARGAYTAYMGNGTNGTNGCNATHGAYATGMGNGGNTAY GGNGAYTCNAGYMGNCCNGTNGGNACNCARCARTAYACNYTNGARTGYYTNGTNAARGAY GTNAARCARATHATHACNGCNYTNGGNTAYAGYTCNTGYATHYTNATGGGNCAYGAYTGG GGNGGNGCNATHGCNTGGGCNTTYGCNGGNTGYTAYCCNGAYATGGTNGAYMGNGTNGTN ATHATGAAYAGYCCNCAYGCNMGNGTNTTYAARAARTAYYTNCARACNCAYYTNGCNCAR TTYAARAARAGYTGGTAYATGTTYTTYTTYYTNGTNCCNATHYTNCCNGARATHTAYATG GGNYTNAAYGAYCAYAARCCNYTNGAYGTNATGTTYAARGGNMGNAGYAARGGNGTNAAR ACNGAYGCNACNACNACNCARGAYGTNGARGTNTAYAARTAYYTNTAYCCNAAYMGNCAY GCNTTYACNGGNCCNATHAAYTAYATHMGNGCNGGNYTNTTYTAYCCNACNACNTCNTGG YTNTGYCARAARGTNACNAARCCNATHYTNYTNYTNTGGGGNTGYMGNGAYYTNGCNYTN GARACNGGNYTNGCNCARTGYTGYCARGARTAYGCNTAYGAYYTNAARATHCARTAYYTN GARGAYTGYAGYCAYTGGGTNCARATGGAYCAYCCNCARGARGTNAAYGGNTTYATHMGN GARTTYGTNTCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARACNYTNYTNGGNYTNACNTTYTCNGAYGAYMGNCCNATGGTNTAYAAYGCN ATHATGACNGCNAAYYTNATHYTNGCNTTYATGTCNTTYGCNATHGTNATHATHTGYACN TCNYTNYTNGTNTCNAARYTNAAYCARAARACNAARTGGMGNGGNGCNAAYGTNAARGGN CARGARTCNYTNGARACNATGACNACNMGNGAYCARMGNGTNAGYAARATGGTNATHYTN ATHTCNTCNGTNTTYATGGGNTGYYTNACNCCNGGNGTNATHYTNTCNATHGTNATGYTN TTYGTNCCNGARTTYAGYAARGGNMGNGCNTAYCAYAAYYTNTTYACNATGGTNTGGGCN ATHAAYCAYATHACNGARGCNYTNAAYTCNTCNGTNAAYATHTTYATHTAYTAYAAYATG AGYAAYMGNTTYMGNTCNACNATHMGNAGYATGTTYATGYTNMGNAARATHACNACNGTN GCNMGNYTNGTNCCNMGNGTNMGNAAYGCNMGNTCNATG---GGN------GGNGTNCCN GCNCAYTTYAARCCNATHMGNCARGTNTGYGTNGARCAYAARAAYACNATGGAYTTYYTN CCNGTNCCNTCNGGNTCNTGGCARGARGCNTAYAAYGCNACNAAYTCNCARAAYAAYATG YTNYTNYTNGGNAGYYTNACNTCNGCNATHGTNACNATHGCNATHYTNTTYCARACNGGN TGYATHTAYYTNCAYGGNCCNCCNCCNGCNTAYAAYYTNAARGAYAARMGNTCNAGYATH AARGTNCCNCCNMGNTTYAAYAARYTNGTNGCNGARAAYCAYGCNYTNYTNGARAARTGY TCNGCNGCNAARYTNGTNAARMGNATGCCNAAYACNGAYGTNGCNCAYAGYTTYGTNCAR MGNYTN---AAYGGNATGAAYAARGTNAGYGARGARYTNTGGACNAARGCNAARGCNYTN ACNTGYYTNCARAGYCAYCARYTNATGYTNAAYTGYYTNAARTCNYTNGAYATGGARGCN YTNTCNGARGCNACNCCNTTYCARACNGTNTAYMGNACNAARMGNYTNYTNGARYTNATH YTNACNAARTTYGCNCARACNCARGAYGARTCNGAYTCNTTYTCNAARGTNCARTTYMGN CCNTGYMGNCCNAAYGGNTGGTCNTCNTCNTCNACNTCNYTNATGGAYGGNAARGAYGAY GAYATHGARTGYYTNTTYGGNTAYCCNAARYTNCARGTNCARGARGAYTAYTTYGTNACN GAYGCNYTNGCNAGYTCNAARACNTGGTCNCARYTNCAYTTYCARCAYAARYTNCAYMGN ATHCARYTNCAYYTNYTNTCNYTNTCNGARGCNGARTGGTGGCCNGTNYTNTCNGARAAY CCNACNAAYGGNAGYGTNGTNCARATGATHCAYAGYYTNYTNACNTCNAGYGGNGARTTY TTYCCNGCNATHGTNGARAAYCCNTAYYTNGTNTCNTCNYTNMGNACNGCNYTNGARGAR GCNAARTTYMGNATHGTNMGNYTNMGNGAYGARAAYGAYCARAARGAYGAYATHATHGAR GARGARMGNAAYCAYMGNATHGCNYTNGARGARAARATGGARAARTAYYTNGTNGAYYTN TAYCARAAYCCNAGYGTNAAYGAYGARYTNMGNCAYMGNYTNCCNMGNGCNAARAARAAR GGNYTNYTNGAYATGCARMGNCARCCNCCNGCNACNAGYTAYAGYYTNTTYGGNTCNACN AAYAGYCCNYTNTAYAGYMGNACNGTNGGNGTNAGYGCNGARTCNAARTCNYTNGAYAGY YTNGAYTTYTGYAGYMGNGARTGGGARMGNTGYYTNGARCARTGYAGYCARGTNYTNACN CARGCNAAYACNATHTTYAAYAAYATHAGYAGYTCNGCNGTNTGYAAYGARGTNYTNAAR TCNYTNCARGGNTGGGARTAYGTNTCNTGYGTNATHGARATHTAYMGNGTNGCNTGYMGN GTNATGACNTCNATHMGNTCNACNGCNATHTCNAGYGAYGARYTNGARCARACNYTNAAR GAYATHGAYYTNATGTGGAAYAAYYTNTCNGCNTTYYTNGTNGGNGCNTCNYTNYTNCCN GAYCCNTCNTCNYTNGTNTTYACNAGYGCNGTNYTNAARAGYGARCARGAYTCNAGYTCN TCNTCNGCNTGYGGNATHTGYYTNYTNAAYGTNTAYYTNAARAARACNATHAARCCNAAR CARYTNGTNCCNYTNMGNAARCARGCNAARGARAARGCNAAYAARGARTAYGAYTGGGAY GAYCAYYTNATGTCNMGNYTNAGYAARYTNACNGCNAAYTGGATHGTNCAYCARAARATG GTNGGNGARMGNAGYAARGARAARYTNACNAARACNYTNGARTCNTGGTAYGGNGCNCCN ATHCAYACNGAYYTNGTNMGNGARGARACNAGYGAYGAYGARGARGAYGCNAARAARMGN GARCARAARCCNAARTCNAARTGGAARAARNNNGARGCNGCNYTNYTNGARMGNGTNTAY AAYGTNACNCCNCCNCCNGTNGARGCNYTNGAYCCNTAYTCNGAYGAYAGYAARGCNCCN TTYTAYMGNCARCCNGCNGGNATHMGNAARAARAARAARAAYGARGARAARGARGARGCN MGNGCNATHAAYGCNACNGCNCAYAAYATHGARATGAARMGNMGNCCNGAYACNCCNCCN YTNACNGTNMGNGAYTAYYTNCCNCCNGGNGTNGGNGAYAARGTNTAYCAYACNGAYAAY MGNTTYCARCARGARTGGYTNACNGGNAAYAAYCARATHTTYCAYYTNGAYGAYCARYTN ATHAARATGGAYTCNAAYAAYAARTTYMGNAARAAYYTNCARMGNGARATGCCNCARCAR CCNAAYATGTGGTAYGAYYTNGGNTCNGAYGAYAARCARGARACNAARGCNGGNAARATG TCNTTYAARCCNCAYAARGGNCAYAARMGNTGGATHGGNYTNCCNGTNACNGTNGARGAY AAYYTNGGNATGYTNAARGAYATGACNCCNGGNTTYGAYCCNGTNTTYYTNAARGARCCN GAYCCNAARCAYAARMGNAARATHAARCARAAYAARATHYTNGGNGCNATHGTNCAYGAY TGGMGNAAYAARTGGTTYYTNAAYGGNCARTTYGCNGAYGCNACNCCNGAYGAYYTNATH MGNGAYATGGCNGAYATHCARCCNCAYGTNMGNYTNAARGCNGTNGGNACNGTNGCNAAR GCNGCNGARTAYAARCCNCCNACNGAYTCNAGYATHGCNYTNGAYTCNTCNGTNCAYGAY CCNATHAAYGAYYTNCCNGARCARATHTTYGTNGCNYTNGARTGYYTNYTNGAYGAYAAY AAYGAYCARGTNCARAARGCNGCNGCNATHACNYTNTAYTCNYTNGAYMGNCCNTCNGAY AARGCNAARGTNMGNYTNMGNGAYATGYTNAGYGTNGARAAYACNATGGAYMGNTGGGCN GCNGCNCARTGYYTNGCNCAYTAYGGNGARTGYGAYTCNGAYGTNGTNGCNGARATHATH AARCARATHYTNGAYTCNGARTCNGCNATHAARCAYGARCARGGNATGGCNYTNYTNGCN AARATHAGYAAYAGYAGYACNYTNGTNCAYTGYATGGTNGCNGARCARYTNAAYAGYAGY AGYTGGMGNTAYMGNGTNATHGCNTGYAARATHYTNCCNACNYTNTTYGGNTCNATHAAY MGNGAYATHACNCARAARYTNTCNGARYTNATGTGGCAYGAYTGGCAYGTNGARGTNMGN AARGCNGCNGCNCARTGYYTNGGNAARACNAGYCAYGGNMGNGAYGTNCAYGAYGAYATH MGNGAYMGNATHYTNCAYGGNACNGARMGNACNAARATGGARGCNATHAAYAARYTNGGN CARYTNGGNATHATGACNGCNAARYTNYTNCCNGCNTTYYTNGAYTGYTTYACNGAYTCN TAYGTNTCNATHMGNTGYGARGTNTGYATHACNTGYGGNAAYYTNCARATHAARGARGAR CARGTNYTNGARMGNYTNGTNCAYYTNGCNACNTTYGAYCCNATHTGGAARGTNAARGCN YTNGCNATHCARGCNYTNGGNAARATHGGNGARGTNAAYGARGAYATHAARGARTGYYTN YTNTGGGCNATGMGNTAYGARGARMGNCCNGGNGTNMGNGCNGARGCNTGYCAYTCNYTN GTNGCNYTNGAYGTNGAYGAYGARGAYGTNATHGARATHGTNCARAAYMGNYTNYTNGTN GARTCNAAYCARYTNGTNMGNGARGARATGATHGARGCNYTNTCNGTNTTYGGNTAYAGY ACNTCNGARGAYATGGAYACNGTNGCNCARATHAARGCNGARGTNMGNAARYTNTGYACN MGNAAYATHATHGCNTCNCARATHATHGTNAAYGARAAYGAYGARACNAARMGNGARCAR YTNAARMGNAARGTNYTNCARACNGARAARGAYATHGARACNYTNAAYGARMGNAARCAR GTNATHYTNMGNMGNATHMGNTCNCARGCNMGNAGYAGYMGNGCNAGYAAYAARGAYAGY YTNAGYTCNTCNCCNCCNCCNMGNACNTCNACNCCNYTNCCNACNGTNAARATHGGNTCN CARAGYAGYGCNACNACNCCNGARCCNGTNAGYMGNGARGGNACNGTNTTYACNCCNACN GCNGAYAARGARYTNGARGCNATHYTNAAYCAR---GAYGARGTNGTNACNGARTCNACN AGYGGNGGNGGNAARTCNMGNCCNGTNACNGARGGNTCNATGGARGGNGGNGAYGAYGGN GCNCCNGARACNCCNGGNGAYAARGARAAYGAYGAYGGNGGNCARGTNGTNTCNAARATH ACNATHACNAARGCNGAYGAYGARAAYGAYGAYGAYGAYGARTTYGARGAR---GGNAAR AGYAGYGAYCAYYTNCARAAYAAYGTNCARYTNAGYYTNCCNMGNAGYCARGCNGGNYTN YTNTCNCCNATGGGNTCNGCNGCNGAYYTNCARMGNTCNMGNYTNACNGTNAGYMGNATH TCNGGNAARMGNTCNATHATHAGYMGNGAYAGYYTNMGNGARMGNGARAARYTNAAYGCN GARGTNAAYACNATHTAYGCNGAYYTNAAYGCNMGNTAYGCNGAYATGATHCARCAYYTN GTNAARATHGAYAARGGNYTNAAYACNAARGGNTCNTCNGCNGARTCNAGYACNGTNGAR TCNYTNAAYGTNTCNAAYGTNGGNTCNAGYCAYATHGCNMGNYTNAGYCAYCARGARATH ATHGAYACNATHAARGARTCNGCNMGNCARGARAARGGNGCNGGNGGNGARAAYCARTCN GGNGARGGNATHATGGARGGNGGNGCNGARACNACNGGNGARGARACNMGNGARGAYGGN GAYGAR---YTNTAYAAYGARGAYGARGAYMGNCCNTAYGCNGTNCARGGN---CARGAY GCNGARTGGAARTCNTTYGTNGAYACNYTNTCNCARGAY---AAYACNGARGAYATHACN ACNTAYCCNTTYGTNGARGAYAAY------------------------------------ ------------------ATGMGNTAYGCNAAYTCNGARAGYTTYGARTTYYTNGARCCN GAYCARATHGAYGARGCNAAYGTNGTNGARTAYYTNTCNYTNGGNYTNAARCARTTYGAR ACNATHAAYTCNGGNGGNGARACNTGGCARTGYGCNTGGGCNCCNGAYAAYTCNTAYTTY GCNTGGTCNAGYGGNCAYAGYATHGTNCAYYTNGTNCCNTGGAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNTCNGARATGAAYYTNTAYATHCARGGN CAYTCNGAYACNYTNYTNGTNYTNYTNATHGARAARGARGTNACNTGYAAYAARAGYTAY ATHCAYAGYYTNTGGAARTCNTGYYTNTCNCAYYTNGGNGARYTNGAYTTYGARGTNAAR AAYGTNGARMGNCAYAGYAARGAYGAYTCNGARGCNYTNTAYCARTAYATGAARTAYGAY TCNTTYTCNCARAGYYTNAAYGGNTCNGCNYTNYTNCCNGTNACNAGYYTNGCNAAYGAR ATGGTNGAYTCNTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNAAYYTNGGNYTNAARAGYAGYTCNYTNGCNCCNACNGCNTGYAARYTN TCNACNCARTAYATGGTNYTNGAYCAYATGACNAAYCAYTAYAAYAARATHTCNCARGCN AARCCNGCNATHGAYAAYAARCCNCCNAARAGYATGACNACNAGYCARAARATGMGNGAY MGNAARACNMGNGCNMGNGCNYTNTCNCCNCAYMGNAAYMGNCCNATGTCNAGYATGTCN CAYGGNTAYCAYGAYGAYGTNCAYGAYTAYCARGARTTYYTNAAYGARGARCCNGARGAY GARGARGGNMGNYTNGTNCARTCNATHATGAARACNACNYTNGCNAARAARTCNAAYGGN AGYAAYGARGCNACNTTYAAYTCNAARACNCARACN---TTYTCNCARTCNACNGARACN ATGGTNMGNCARGARAAYGGNACNATGGCNGGNGGNGARCAYCARMGNACNACNTGGCAR MGNCCNATGTCNGCNMGNTCNGGNCAYTCNGTNTCNAGYATHAAYGGNACNCARMGNGTN CCNATHACNTCNCAYGAYCCNAARAARATHACNTAYAAYGGNGAYYTNYTNGAYAARMGN TCNTAYTGYTTYACNGARCCNGAYMGNCCNTTYACNCCNMGNACNYTNAARAGYAGYCAY CARTCNMGNYTNAARTCNTCNAARTGYTAYAAYGCNCCNAARCCNAAR------GGNGGN AARYTNTCNGAYATGGARTCNYTNMGNCCNCARCCNMGNCCNCARCCNMGNCARMGNAAY MGNTCNGGNCARTCNGAYCARTTYGGNGARACNATGCCNACNAAYCARYTNTCNGARTCN ATGYTNATGGAYATHACNYTNCARAGYMGNGAYGGNMGNCAYGCNCARGARGGNAARMGN GAYGTNCCNCCNYTNGCNATHTCNATGGAYACNGAYCAYTTYAARTGGYTNCARGARCAR GCNTCNAARGCNCARGTNMGNGCNMGNTAYAGYTCNAARATHCCNMGNGCNGAYATHACN ACNGAYGGNATGCARGARGGNGARGAYGARAGYCCNYTNAAYYTNAGYCAYTCNATHMGN YTNGARACNYTNAARAARGARGARGARCARAARTAYYTNGCNTTYGTNAARGARGTNACN GAYGAYGTNYTNACNMGNGGNATHTCNACNGAYAARGTNYTNCAYMGNGTNTTYGARAGY CAYATHGARMGNMGNAARGGNGAYYTNGAYGARACNMGNATGMGNGCNATGATHAARGAY YTNAARAARGAYYTNGGNYTNMGNGAYATHTCNGTNGARMGNAARGARAGYCAYACN--- AAYACNGAYAAYMGNGAYTCNACNYTNTCNAGYAARCCNGARGTNAAYACNGGNACNAGY AAYATGGCNATGACNATGGARTCNACNTCNACNATGCARTTYGGNCARACNGGNGAYYTN TTYAGYACNATHCAYTCNGARMGNGAYAAYYTNGGNGARYTNGTNGARATGTCNGAYAAR GARAAYGAYGARYTNACNGCNACNCARGTNYTNAARGARTAYCARATGAAYYTNACNGCN AARGARGCNAGYGGNGAYAGYTCNGARGTNAARGGNAAYGGNGGNAGYGGNGGNGGNGGN GCNMGNGAYGARMGNCCNGCNACNGGNGARMGNMGNTTYAARATHMGNCCNYTNAARGAR GAYGARTGYCARCARGTNATHGAYATGGTN------------------------------ ---TTYGARYTNGCNGARTTYGARAARATGGGNGAYMGNGTNAAYAAYACNGCNGARGGN YTNMGNGARGAYGTNTTYGGNCARCCNCARMGNTGYCARTGYYTNGTNGCNGARGAYTCN AARAAYACNGARATHGGNYTNGTNGGNTAYGCNYTNTAYTTYTAYGCNTAYTCNACNTGG GARMGNGCNTTYATGCAYYTNGARGAYYTNTAYGTNAARCCNGAYTAYMGNGGNAARGGN ATHGGNAARAARATGTAYCARGCNTGYGCNCARATHGCNYTNGAYYTNGGNTGYCARMGN YTNCARYTNGAYGTNYTNGGNTGGAAYAARCCNGCNAARGAYTTYTAYGARMGNGTNGGN AAYGARGAYAAYACNGARACNGARGGNTGGCAYAARATGMGNATGGGNMGNMGNCARATG GARCARTTYGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNCCNTTYACNTCNTCN ATHACNCCNCCNTCNACNTCNGCNYTNGTNCARCARAARAAYGARAAYATHACNCARYTN GARAARCARYTNGARAARGARMGNGARGARAAYMGNMGNYTNAARCARGARATGGARGAR AARGAYAARAARATHGCNGARYTNCARAARTCNGTNGARYTNYTNAAYNNNMGNTGYGAY GGNYTNGAYGARGAYAAYYTNAARYTNCARGARGARAAYAARGCNYTNATHMGNGCNATG TCNAARYTNAGYCARAAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARGAYATHCCNGARGGN ---TAYTGGAARGAYYTNGCNGARCARMGNMGNCARGCNYTNAAYGAYACNYTNGARGAR AAYGARAARYTNTCNYTNGARGTNGARCARYTNAARGARGARAAYMGNMGNYTNTCNAAY ATHGCNTCNAARGCNGARTAYYTNGARAAYATHATHCARAAYGCNYTNTCNGAYGAY--- TCNACNACNTCNTAYTGGGGNGARATHCCNGARGTNTCNGAYACNGAYTCNGGNATHGCN GCNYTNGARMGNGARCARATHACNAARCCNAARCCNATGGAYGTNGARGGNCAYYTNYTN CAYCARCCNTCNAAYMGNCAYCAYCCNCCNACNAAYGARATHYTNGCNACNGAYCAYTTY AARATGGAYCCNGTNGTNYTNCAYACNATHMGNYTNYTNCARCAYATHAARAARGTNMGN GCNGCNATHGARTCNYTNCARCAYGAYATHAARTCNGARACNGARGTNTCNAGYATHAAY GTNGGNCCNGTNCCNGARTAYGAYGGNCCNCARATHAARGAYMGNTCNMGNCARAARTAY TTYACNGARGARGARTAYGARAGYGAYTTYGTNAARGGNATHCCNAARCCNCARCCNGCN ATHGAYGARTCNACNTGYMGNMGNYTNYTNMGNMGNTCNACNGCNGCNATHTGYTCNCAY YTNTCNATHGAYACNGCNCCNGARTCNGTNYTNGAYACNYTNACNGAYGTNTGYCARGAR TTYTTYTCNCARTTYACNMGNCAYYTNGGNACNGCNACNGAYMGNMGNGCNATGCAYGGN AGYGGNGGNTTYCCNGAYTCNATHGARMGNGTNYTNCAYGARYTNGGNATHGGNAGYGTN ACNGARYTNCAYACNTTYTAYCARCARMGNGTNYTNGCNTAYCAYAGYMGNACNGARMGN CARTGYCARTCNYTNGTNACNGARTAYAAYACNYTNAARMGNCARCCNCARCCNTCNTCN TCNTCNTCNTCNTCNTCNAGYATG---GGNGGNGAYACNYTNCARGTNATHMGNATHAAR GAYGARCCNAAYTCNTCNATHCARTTYCCNYTNYTNGAYGAYAARGAYGARGTNGCNGAR GCNGARCARYTNYTNAAYATHGARAAYYTNGGNCCNTTYGARATHGTNGARCARGARATH CCNACNGGNYTNACNACNGARATGAARGGNAARGGNATGCARGCNAARGGNGGNGGNGCN GAYAGYMGNGCNTCNAARATGTCNATHTGGAGYTCNGTNGAYGARTCNAGYGAYAAYCCN GCNAGYAGYAGYCAYGAYATGACNACNACNGTNCCNACNCCNCARTCNGGNGGNATHCCN TCNACNCCN---CARGTNGGNGTNCCNACNCCNMGNGARGGNGGNGCNGGNGCNTCNGCN GAYATHCARGARCCNGGNTCNATHAGYAGYACNGAYATGTTYTCNCCN------ACNCCN GGNCCNAGYAARCCNAARAARAARAARAAR------------------------------ ---------------------ATHCARYTNTCNAARACNCARGCNYTNYTNAGYGARAAR GTNTGYATHTCNGTNACNGGNYTNAARGCNAAYCARAARGTNACNYTNCARACNTAYGTN GAYGARGGNAGYAARAGYTTYGGNTCNTGYGGNCAYNNNNNNGCNGAYNNNGARGGNNNN GTNAAYACNTTYGARCAYGARTGYCAYGGNGGNACNTAYGAYGGNNNNGARCCNATGGGN YTNTTYTGGAGYATGNNNNNNNNNCCNGGNNNNNNNNNNMGNMGNATHYTNAAYACNGAY GTNNNNMGNCCNGTNGAYGTNGARATHTCNNNNNNNCCNGAYCAYGTNNNNTTYGAYGAN YTNCCNTGGACNNNNCCNNNNCARCCNYTNGCNTCNNNNNNNTTYNNNCARAARTTYNNN NNNGARGGNGTNNNNGTNATHCCNNNNNNNGARGAYGGNGTNGTNGGNACNYTNNNNYTN CCNGARGGNNNNGGNCCNTTYCCNGCNGTNATHGANNNNTTYGGNNNNNNNNNNNNNNNN CCNGGNCAYMGNTCNTCNYTNYTNGCNTCNNNNGGNATHGCNTCNTTYAAYYTNNNNTAY NNNNNNNNNNNNNNNYTNGCNNNNNNNNNNNNNAARATNNNNYTNNNNNNNTTYYTNAAR GCNTTYGAYTGGYTNTCNNNNCAYCCNAGYGTNNNNCCNAAYGCNYTNGGNNNNGTNGGN AGYTGYATHGGNGCNNNNTAYNNNTCNYTNATHNNNTGGAARMGNCCNAAYNNNMGNTGY TTYGTNAGYATHAAYAGYCCNNNNMGNCCNGARNNNCCNACNCARNNNGTNGARGGNGAR NNNGTNGARNNNNNNNNNNNNCCNTGGNNNNNNNNNNNNGARNNNGAYGGNGCNNNNNNN NNNNNNNNNNNNNNNNNNGTNGARGAYAAYNNNNNNTCNYTNCCNTAYTGGMGNCAYGGN NNNAARNNNYTNNNNNNNNNNNNNGARGAYGAYCARTGYNNNAAYCCNGAYTGYYTNMGN NNNAGYCAYNNNNNNNNNCCNNNNGARYTNNNNNNNAAYNNNGARTTYNNNAGYTAYCCN GGNGCNGGNNNNATHYTNGANNNNCCNNNNNNNCCNYTNTGYNNNAANNNNTAYNNNNNN NNNYTNNNNNNNATGNNNYTNTGGGGNGGNNNNCCNAARGCNCAYGCNNNNGCNCARGAR GAYAGYTGGNNNMGNATHNNNNNNTTYYTNNNNNNNAAYYTNATHCAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNAARAGYYTNCCNGARGARAARTTYGTNYTNCCNYTNCARAAY GAYYTNACNAGYGCNTTYACNACNGTNGAYGGNGARYTNTTYCCNGCNTCNTTYCCNGAR ATGATHMGNGAYAARGARTAYYTNACNGAYGTNGGNTTYTAYGAYMGNGARTAYYTNGTN ACNYTNACNAAYAAYGARGGNCARYTNATGTCNTCNGGNCCNTTYGCNATHGAYGARGAY ACNATGAGYCCNGARMGNGTNGGNYTNCCNGARTCNATHTTYCAYMGNGCNATGGAYTGG TAYAGYCARGCNGGNCAYCAYACNGTNGCNCCNATHAAYGAYYTNATGATGGAYCCNYTN ATHYTNYTNCCNTCNATHGAYTTYYTNAAYGTNGCNGCNGAYAARGGNGGNCCNTAYTTY YTNGTNTTYGAYCAYTGGCCNTCNTAYTGYCCNGAYMGNCCNGAYGGNACNGTNCAYAGY YTNGAYYTNTGYTAYYTNTTYGAYATHGARCCNGAYGARATHTAYMGNACNTAYAAYGGN CARMGNACNGGNAARGGNTTYACNGARGARGAYMGNCARYTNAARMGNYTNTTYATHAAY ACNGTNGTNGAYTTYATGCAYCAYGGNAAYGCNGAYTCNACNATHACNCCNCAYYTNGGN GARAARTGGCCNCCNTTYGAYTCNACNAAYGARTTYTAYYTNAARTTYGGNCCNMGNCCN GCNGTNAARCARTTYCCNTTYAAYGARMGNMGNAAYYTNTGGGARAAYGTNGTNCCNAAR TGGGARACNGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATHCCNTAYATHAAYATGMGNAAYGAYGAYGTNATHGTNTGYGCNTAYCCN AARGCNGGNACNCAYTGGGTNTGGGARATHGTNMGNTGYYTNCARGCNGGNACNATHACN GTNCCNYTNATHGARAARGAYAAYTAYATGYTNGARTGYAARGGNAARGARTAYATHGAY TAYYTNCCNTCNCCNMGNGTNYTNAAYACNCAYYTNMGNTAYGAYCARYTNCCNGARGAY GTNMGNTCNAARMGNTGYAARYTNATHYTNATHAAYMGNAAYCCNAARGAYYTNACNGTN TCNATGCAYCCNTAYTAYTAYGTNCARTAYGTNCCNATHCCNYTNAARCARGAYYTNGAR ATGAARGTNAAYTGGGCNGCNCARCCNAGYACNGCNCCNAARCARGAYACNAGYAARCAY TTYCAYGTNTTYGTNGGNGAYYTNAGYTCNGAYATHGARCARCAYCARYTNMGNGAYGCN TTYTCNATGTAYGGNGARATHTCNGAYTGYAARATHATHMGNGAYCCNGCNACNTCNAAR TCNAARGGNTAYGGNTTYGTNTCNTTYGTNAAYAARACNGARGCNGARACNGCNATHTCN GGNATGAAYAAYCARTGGYTNGGNACNMGNCCNATHMGNACNAAYTGGGCNACNMGNAAR CCNYTNGCNCCNGTNGTNAARGARAAYTCNAARCCNYTNCARTAYGARGARGTNTTYTCN CARTCNAGYTCNACNAAYTGYACNGTNTAYTGYGGNGGNGTNACNAAYGGNYTNACNGAR GARYTNATGMGNAARACNTTYTCNCARTAYGGNACNATHCARGARGTNMGNGTNTTYAAR GAYAARGGNTAYGCNTTYATHMGNTTYAGYACNAARGARGCNGCNACNCARGCNATHTGY GCNGTNCAYGGNACNACNATHAAYGAYCARCCNGTNAARTGYTCNTGGGGNAARGARTCN AAYGARTCNAGYCAYACNAAYCARCARTCNAAYAGYCCNCCNGTNGTNATGGTNCCNTCN CARCARCARCARCCNATHGCNGCNACNCCNGCNGCNAAYCCNTAYGGN---GGNTTYTAY AAY------TAYTAYCAYAGYGCNCCNTAYGCNACNGGNGCNCCNACNTAYCARAGYGCN ATGCCNGCNCARGGNCARTTYATHCCNGCNGCN---GGNCARTGGGGN---GGNTTYTCN AAYTAYCARGCNTAYGGNAAYATGAAYATGCCNGTNAGYGGNTAYACNGGNYTNCARATG CARCCNGGNGCNCARCARCARCARTTYGGNGGNCARGGNCARGGNATGGTNGGNTAYCCN ATGCARCARGGNATGGCNMGNTCNAAYGTNMGNTAYGARGTNYTNCCNTCNGARGARCAR AGYATHGCNGCNGARCCNGTNGAYGTNGCNATGGTNGTNCCNCCNCCNAGYTAYACNGAR AAYGCNGTNATGGARCARGAYGGNGAYAAYCCNGCNTTYGGNCCNGCNAARYTNCCNAAY TAYGTNGAYGCNACNACNYTNCCNACNTAYGARGARGCNGARMGNAGYAARGCNGARGAR ------TCNGCNAAYTCNAGYAAYMGNGAYTGYGARACNGGNMGNATGACNTCNATHAAY GGNGTNAAYGARGCNACNATHGGNACNGAYGGNATGTTYATHTGYACNTTYTTYATHTCN TTYYTNTTYAAYTGGYTNGGNTTYYTNYTNTCNYTNTGYYTNTCNAAYACNATHGCNGGN MGNTGYGGNGCNYTNTCNGGNYTNGGNYTNTCNATHGTNAARTGGGTNGTNATHGCNAAR MGNAAYAAYTGGGGNACNGAYTTYGCNGAYGGNGAYTCNTGGYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARAAYTCNTCNTAYYTNAAR GAYATGGARACNCARAAYAARAAYYTNATGGAYTCNGTNAARAARYTNGTNAGYGTNAAR GARGAYYTNGARATHMGNGGNAARAAYYTNTCNTCNMGNYTNAARTCNAARGCNGGNGAR YTNAAYGTNCARGCNTCNGARATHAGYMGNYTNAAYGARCARAAYAARAAYYTNGARTCN AARYTNGCNAAYGGNAAYGARACNATHMGNAAYYTNAARGCNGARGTNGTNGCNTGGAAR AAYMGNTAYTGYACNGCNAARGAYGARACNGAYMGNYTNACNACNGAYAAYGGNGCNAAR GAYGCNCARATHCARAAYYTNACNGCNCARYTNCAYGARACNYTNCARCARACNATGGCN YTNCARAARGCNYTNTTYACNAGYTGYGARMGNGARAARTGYAARGARGARATHATGYTN TCNYTNMGNAARCARCARAARMGNACNATGCARGARATGACNAAYYTNMGNAARYTNTAY GARAARCARACNAARGAYYTNAARYTNTAYCAYYTNAGYGTN------------------ ------------------------------------------------------------ ------------------------------------------------------ATGTCN NNNGARATGGARATHGAYNNNGTNAAYMGNGAYCCNAAYAAYYTNAAYGAYCAYGTNNNN GTNTGYTTYGAYGARGTNATHGGNGARCCNGAYGGNGCNCAYTCNATHAAYTGYGTNTGG GTNAAYAGYTAYAARTGYTTYAAYTGYTGGAARAGYTGYTGYTAYAAYTTYYTNACNATH ATHTGYGCNATHCCNATHGCNATGTGYTGGGGNTGYGARTTYGCNGCNATHACNTTYACN CAYGTNTGGCAYGTNACNCCNTGYATGMGNGCNTAYATGATHCARTGYGGNTGYATGCAR AARTTYTAYGGNACNTGYYTNCARTGYTAYATHCARCCNTGYTAYGARGCNATGGGNTTY ATGTTYAAYAAYATHMGNGTNACNAAYGTNAGYCARMGNACNMGNGARGARGARYTNMGN ACNCARGTNYTNAAYYTNGARACNCARGTNAGYAAYAARCARGGNGAYGTNGAYMGNYTN GARMGNATGYTNGARGTNGTNAARCARGARTGYAGYYTNCARGTNGTNGAYAARGTNGCN AGYGCNGARMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATGTCNACNTCNAARATHTCNGCNAARGTNTCNAAY TGGAAYCARGARACNAARGCNMGNYTNAAYGARAARATHACNTCNAAYGTNAAYGAYGTN GGNTCNYTNGTNMGNCARYTNATHMGNGGNTCNAARACNAAYGARTTYYTNGCNCARGCN GCNAARAAYTTYGCNTCNCARGARAGYTAYATHCARAAYTCN------------ACNGAR ACNATGAARAARATGGAYGTNGTNMGNTCNCAYYTNGARTTYCARCARTCNGCNATHTCN MGNAGYYTNCARCAYYTNGAYGARGTNCARGAYCARYTNTCNACNYTNCARCAY------ ------------------------------------------CCNTCNGARMGNGCNTTY GAYTGGTAYYTNGARAAYATGAAYAARCCNGGNGAYCAYGTNGTNYTNGTNCAYTGYTCN CARTTYCARYTNCAYYTNGGNYTNCCNGGNGTNGCNGTNAAYGTNGAYAAYGTNAGYAAR CARGTNGARGARGCNAARGARAARACNGAYYTNATHATHAGYAARGCNACNACNGTNYTN MGNGARAARGAYATHATGTCNCAYTCNGTNGTNAARAGYAAYACNAARCCNCAYGARGCN ATHYTNGARGCNGCNGARGARGARGGNGTNGCNCAYATHGTNATGGGNACNMGNGAYYTN GGNAGYGTNMGNMGNGCNTTYGTNGGNAGYGTNAGYACNGARGTNGTNMGNAAYGCNCCN TGYCCNGTNACNGTNGTNAARACNGARGAYATGGARAAYYTNAGYYTNYTNGGNAARGTN GCNATHNNNACNGGNNNNAGYTCNGGNATHGGNMGNGCNNNNGCNATHYTNTTYGTNMGN MGNGGNGCNAARGTNGCNYTNAGYGGNMGNNNNNNNNNNAARNNNNNNNNNNNNGCNGAY GARTGYAARNNNGCNGGNGCNAARGANNNNNNNGTNNNNNNNGTNNNNGGNGAYYTNACN NNNGARAGYNNNMGNCARNNNYTNGTNGARAARACNNNNAGYCAYTTYGGNCARYTNGAY ATHYTNGTNAAYAAYGCNGGNMGNNNNGCNNNNGARNNNYTNGARAGYYTNACNGARTCN NNNYTNGAYNNNATGNNNNNNATHYTNTTYAARGCNCCNATHTTYYTNACNCARNNNGCN YTNCCNCAYYTNAARAARACNAARGGNTGYNNNGTNAAYNNNTCNACNNNNNNNACNNNN GARAAYNNNCCNGGNTTYTTYTCNTAYACNGTNNNNAARCAYGCNTTYGAYAARTTYACN GARTAYGCNGCNYTNGARTTYMGNNNNNNNGGNATHMGNGTNAAYTCNGTNAARCCNGGN NNNNNNGARACNNNNNNNTTYNNNNNNNNNTTYAARGGNGAYAANNNNCARATHAANNNN TTYYTNGANGGNCARAARNNNYTNNNNATGYTNNNNNNNAAYGGNCARCCNNNNGAYNNN GCNGARNNNNNNGCNNNNYTNTCNTCNAANGCNGCNNNNNNNNNNACNGCNNNNCAYTTY NNNGTNGAYGGNGGNMGNGCNAAYTTYTTYCAYCAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYGAYGAYGAYGAYGAYGGNGARGGNGGNGAYGAR GAYAARGAYGARAAYGARAARYTNAARGCNCCNACNGARYTNYTNATGGARTTYATHGAY TGYYTNATGAARAARGAYTAYCCNAAYGCNAGYAARYTNTGYAARATGATHYTNYTNTAY GARCCNGARAAYGARGARGCNYTNAARTTYCARCCNYTNATHGARGARAARATGGCNYTN GAYGCNGARGCNGARGGNGARGGNAGYTCNGAYGAYGAYGAYGAYGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARCAYACNYTN AARGGNAARTGYCCNATHGCNGGNAAYTCNGTNGGNATGGAYAARMGNTTYATHGAYAAR TAYATGCCNCARYTNGCNGARCAYYTNCAYTAYMGNGTNGTNGAYGTNAGYACNATHAAR GARGTNTGYMGNMGNTGGTAYCCNGAYGAYTTYAAYAAYGCNCCNGCNAARAARTGYACN CAYMGN---GCNATGGAY------------------------------GAYATHAARGAR AGYATHGARGARYTNAARTAYTAYMGNAAYGCNATHTTYAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARAARGGNCCNCARAARCCNCAYCARYTNMGNAAYGTN CARMGNTGYTGYGARCAYAAYATGTGYACNGAYAGYACNATGATHTCNTCNTCNGGNGGN CAYCARTGYGTNCAYGGNMGNCCNAAYCCNACNTTYGAY--------------------- ------------MGNCARATGTGYTAYACNTGYCARTAYGTNCARAAYGGNCCNGGNATH GARTGYYTNACNACNCCNYTNGAYTGGCCNGGNGGNCCNCCNMGNATGAARTGYCCNAAY MGNTGYACNATHYTNGCNGARTTYGAYTCNGCNAGYGGNAARCCNACNTTYTTYCAYMGN GGNTGYGGNGCNGCNACNACNTAYCCNAARGARGGNTGYGCNAARACNGGNGCNMGNGTN AGYTGYTTYTAYTCNTGYGGNGAYGGNAARGAYTAYTGYAAYGAYATGGCNATGTCNAAR GCNCCNGTNYTNGAYGAYGAYGAYGAY---------------AAYGGNAGYCAYGAYYTN GARGARGCNTGYAARATHGCNGCNAAYGGNATHGGNAARGAYTGGAARAGYGTNTAYTCN MGNYTNCCNTTYGAYCCNCCNMGNGAYYTNGCNMGNYTNCARMGNGAYATHTCNGTNYTN GAYCAYATHGCNTAYMGNAGYGAYATHCCNCCNGARMGNCARGCNYTNAARTCNYTNGAR MGNTGGMGNACNYTNCAYMGNAARGGNGAYATHAAYGARYTNATHCARGTNYTNMGNGAR GTNAARAARAARMGNYTNGCNGCNGARYTNACNAAYMGNTTYATH--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYCCNACNMGNGAYTCNATHACNATH ATGTAYTGYGGNACNCAYAARTCNYTNACNYTNGGNATHCCNATGATHGARATHATHTTY GARGGNTCNCCNGAYATHAGYTCNYTNAGYATHCCNYTNYTNATHTAYAAYCCNGCNCAR ATHGTNTTYGGNGCNYTNTCNATHGGNYTNATGCARAAYTGGYTNGARAARMGNACNMGN CARMGNMGNAARCCNGCNTTYAGYTGGTAYTTYATHGGNACNGGNTCNYTNATHGTNGCN GTNGGNTTYGTNTCNTGYGAYAAYMGNATGGTNGCNGTNGCNYTNYTNACNATHGCNGTN GGNYTNGARGGNATGGTNTAYGGNGGNTAYATGGTNAAYCAYGTNGAYTTYGCNCCNGGN TAYGCNGGNGTNATGTTYGGNATHACNAAYTTYATHTCNACNATHCCNGGNATHGTNGCN CCNATHGTNACNGGNGCNYTNACNCCNAAYAARACNCARGAYGARTGGMGNAAYGTNTTY TAYGTNTGYGGNGCNTTYACNYTNATHGGNGCNGTNGTNTTYGGNGGNTTYGCNAARGGN GARACNGARCCNTGGGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ACNCCN GARCARGAYAARAARAARGAYMGNGAYMGNCCNCCNCCNAARATHGTNATHMGNMGNYTN CCNCCNTCNYTNACNCCNGARAAYTTYYTNGARCARGTNTCNCCNYTNCCNTAYCAYGAY TTYTTYTAYTTYGTNMGNGCNGAYATGAGYYTNGGNCARAAYGCNTTYTGYMGNGCNTAY GTNAAYTTYYTNAAYGCNGARGAYATHTTYATHTTYMGNGAYAARTTYGAYGGNTAYGTN TTYYTNGAYGARAARGGNGGNGARTAYCCNGCNGTNGTNGARTTYGCNCCNTTYCARAAR GTNACNAARAARMGNCARMGNAARGTNGAYTCNAARTGYGGNACNYTNGARCARGAYTCN GAYTAYAARMGNTTYYTNGARGCNYTNGARAAYCCNCCNGARACNCCNACNGTNTCNYTN GAYGCNATHGTNGARGARGTNGARGCNAARGARYTNMGNYTNGCNAARYTNAGYGTNACN AARACNAAYACNCCNYTNYTNGARTAYYTNAARMGNMGNAARGARGARAARMGNATGAAY ATGGTNAARYTNMGNGAYGARMGNMGNMGNGGN---GGNMGNGAYMGNGAYTAYGAYMGN MGNMGNTCNGCNAARGARGAYGGNGTNGGNGGNAGYAGYMGNAARGAY------MGNGAY MGNGAYMGNGAYMGNGAYMGNCCNATGGAYMGNGARAARMGNMGNGARMGNGCNMGNGAR ATHGCNMGNGARAARGARMGNGARMGNMGNMGNGAYMGNGAYGGNAGYGGNGGNGGNMGN CARMGNGAYMGNMGNAAYGARMGNGGNMGNTAYCAYCARCARGARGARGARGARAARCCN AARCCNATHATGYTNYTNAARAAYACNGARMGNGARAAYCAR---------------GGN AARGARGARTCNCCNAARGAYMGNGGNAAR------GTNGARMGNGAR---GAYGGNMGN CARGGNAARGARGARCAYGGNMGNGGNGAYMGNGARMGNGAYAAR---MGNMGNGAYTGG GAYGAYMGNCCNCCNGGNGGNGGNGGNGGNGGNGGNGARMGNMGNMGN------------ ---------------TTYCARYTNCCNAGYGAYATHGCNGGNACNACNGARATGACNGGN GARAAYGARCARGGNTCNTGGACNGTNGAYGTNAGYTAYTGGATHAARGCNTGGGTNAAR GGNTCNGAYTCNATHCARGARGTNCARCCNATHGTNATHTAYCARTGYCARCCNACNGAR YTNMGNGARAAYCAYGTNGGNACNGCNGARTCNGCNACNTTYGARATHAARMGNTTYYTN AARAAYAAYATGATHCAYATHACNGTNAARYTNGTNGARAAYTAYAARGCNGCNGGNYTN AAYTCNCARYTNAARYTNATHGTNACNAAYGAYTCNAARATHATHGTNTCNGGNATHGTN ATHAARYTNAARMGNTAYYTNAARTTYCARATHAARGARTGYGAYGCNAGYGTNGCNCCN TGGATGATGACNGAYGGNGARGAYAGYATHGARATHYTNCCNGARYTNGGNCCNCAYYTN GTNTAYTCNTTYAGYGGNTGGTCNGAYTCNGTNATGGGNAARTTYGTNAGYGGNGGNYTN GAYAAYYTNCARATHCCNYTNGTNGAYAARYTNCCNAAYGGNCARAARTTYGAYYTNCCN CCNTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TGYAARGARTGYCARATHMGNGTNCCNCCNMGNTCNCAYCAYTGY AARATHTGYAAYGARTGYATHATHCARMGNGAYCAYCAYTGYTTYTTYTCNGGNTAYTGY GTNGGNTAYTTYAAYCAYMGNTAYTTYTTYGCNATGGTNGTNCAYATGACNTTYGTNGCN TTYTAYTGYAAYYTNTAYAAYTGGAARTTYTTYATHGAYTCNAARGGNGGNTTYGCNTGG ACNACNATHCCNGGNATHATHGCNCCNCAYATHGGNYTNATGYTNGGNGCNTAYGGNTTY CARGARCCNGARCARATHMGNGGNGGNGGNGARYTNTTYAARTAYCCNTGGACNGCNTAY TCNAARYTNCARCARTTYCCNTTYAARTTYTAYTGGACNCAYTCNMGNGTNTTYMGNTAY TTYTTYTAYACNTCNGCNYTNGTNTTYCCNYTNATGGTNAARYTNACNAARGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNGCNGTNCCNAARATHMGNMGNACNYTNGARGGNGTNMGN GGNCAYCCNTAYACNMGNGTNTCNYTNTCNATGACNGAYACNYTNCARYTNYTNAARTGY GGNGTNMGNTTYTCNCCNCCNACNYTNGTNATHACNTAYAARGAYTGGAARTCNGGNAAR ATGMGNMGNMGNTCNATGCCNYTNMGNAAYTTYACNAARCAYTCNGGNATHGARCAYTTY TGYGARGAYYTNAARGCNAAYCCNMGNCAYGCNAARTAYATHMGNYTNTTYGCNCCNYTN CARYTNCARMGNYTNYTNACNATHGTNAARGAYAARATHAGYGGNYTNAGYYTNGARGCN AGYATHGCNMGNAAYAAYCARATGGARAARGTNGAYCCNGARGARAAYYTNAAYACNGTN GAYGARGARACNYTNAARMGNAARAARYTNGTNATGAAYTCNTCNTTYGARAARAAYCAR AARAARYTNGGNGAYCCNGAYTTYGARTAYAAYGTNGARGTNGAYTTYGARGGNGGNGCN ATHGARACNAGYGGNTGGGAYTCNGARGAYTCNGAYATGGAYTTY >barbarensis YTNATHYTNTCNCCNYTNYTNGTNGGNGTNGCNTTYGCNGGNTAYGAYCCNTAYTCNGAY YTNGCNCARYTNTAYMGNATGCARYTNYTNGCNGAYACNTTYGAYGGNTAYGTNCCNGAR AAYYTNCARYTNGARGAYAAYGAYAAYGAYATHGCNATHMGNTCNTAYTGGCCNGARYTN ---------------CARGAYGARGARGARGARGGNGAYGAYAARGTNACNGTNTAYGCN GCNCARMGNTAYAGYGGNGCNCAYATHMGNGAYCARGARCAYATHGARCAYAGYGCNYTN CAYGGNTAYCARTCNGTNTCNGGNGGNACNGTNGARGGNCCNGAYCAYACNAARCARCCN AARAGYGAYAARCCNYTNCCNGCNTAYTGYAAYCCNCCNAAYCCNTGYCCNGTNGGNAAR ACNGCNAARGAYAAYTGYGTNGARGAYTTYGARAAYTCNGCNGARAAYAAYAARAARYTN YTNAGYGARCARGAYTGYCCNTGYGAYACNGARCAYATGTTYAGYTGYCCNGCNGGNMGN GARACNGTNTCNAGYAARGGNCARTCNGGNTAYCARCARACNYTNAAYAARGTNATHGAY CARYTNTCNAARATGGGNGCNGAYGAYAARGTNMGNGAYAGY------TTYGTNTCNCCN GCNMGNAARMGNGTNACNYTNGTNGCNAARAARTCNCCNCAYATHATHCAYAARMGNATG GAR---AGYGTNTAYAAYAAYCCNTTYYTNGTNGGNGARAARAARGAYATHGCNGCNAAR AARGAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CCNGCNATGCAYCARGGNGARAAY GGNTGGATHCCNGAYAARACNCARGAYTGYCCNGAYACNYTNGAYGARGTNYTNGCNTAY TGYAARAARGTNTAYCCNGGNYTNAAYATHACNAAYGTNGTNGARTCNTCNMGNTTYTAY GAYATHCCNAAYTGGCCNATGGGNAAYGCNGGNMGNCARCAYAARCAYCAYGTNMGNCCN TTYMGNTGYYTNGTNGGNGGNTTYCARTCNGAYGCNYTNYTNGTNCCNCARCAYTGYGAR TTYGAYCAYMGNCAYGAYATHACNCARTGYAARGARTTYTCNCAYTGGAAYMGNGTNGCN GARGAYGCNTGYGTNAARAARGGNATGCAYYTNGARTCNTTYGGNATGYTNYTNTAYTGY ACN---YTNGGNCAYTTYAAYGGNGTNGARTAYGTNTGYTGYCCNAAYCCNAGYAAYACN ACNGTNCARCCNGARCCN---AARAAYAAYGAYGAYGTNCCNGAYAARTGGCAYACNACN GAYGCNAGYCCNGARGARGARGARGARGARAGYGAYGARACNGAY--------------- ---------------AGYGARGARAARAARGARGCNGGNACNAGYCAR------------ ------ACNGCNTCNGARAARGTNGTNGAYGARAAYACNATHGAYGCNTAYGARGCNTAY YTNMGNGGNATGCCNYTNCCNTCNACNTAYAAYAAYGARCAYAARMGNTAYYTNGCNGCN AARGCNCARATGATHAARAAYCAYMGNATGAARGARGCNACNYTNYTNCARGARTGGGAR AARTCNMGNGARAAYATGGAYGARGTNMGNAARACNGAYCCNAARACNGCNAAYAARATG AAYGARGARATHGCNATGMGNTTYAARAAYYTNTAYGCNTCNTTYAARCARGARGAYYTN GCNGARAARCARCARYTNYTNGCNYTNCAYCARCARCAYATHCARGCNAAYYTNAAYGAR MGNAARMGNACNGCNATGGAYAARTAYYTNMGNGCNYTNGARTCNGGNGARGARGARAAR GTNGCNAARTAYYTNCAYAGYTAYATHAARGCNGARGARAARGAYMGNATGCAYACNGTN AAYCAYTTYCARCAYYTNMGNTAYTCNAAYCCNAARGARGCNYTNMGNGTNCAYCCNTTY ATHATHAAYCAYYTNAARATGTCNGARATGMGNATHGAYCARGCNATGGAYATGYTNAAR CAYTAYCCNGARGTNGARMGNACNATHMGNCCNGARATHGARGARTTYATGAARMGNTTY AAYGAYATHGCNACNMGNATHAARAARGTNGTNYTNCCNGTNCCNGTNGTNGARGARGAY ------------------AGYGARGARGARACNAGYGAY---AGYGAYTCNACNACNACN GAYGAYGAYATHAGYATHGCNGARGCNTCNCARGAYGARAGYGCNCAYAARTCNGARCCN GARCAR---------GARGTNGAYATGACNGCNAGYAAYGCNTTYGAY------------ ---------------------------GAYGARGTNAARGARGAYGARCAYAGYTAYGAR CARCAYCAYCAYTTYTCNGCNAAYGCNCARGTNGAYACNCAYAAYGTNAAYCAYGGNYTN CAYGCNACNGCNGCNACNAGYTCNCARGTNGGNAGYACNGTNGGNATHGCNYTNGGNAGY GTNTCNGTNTTYGTNATHATHGTNGTNGCNGTNATHATGGTNCAYMGNAAYMGNAAYMGN CCNACNGTNTCNCAYGGNTAYGCNGARGTNGAYCCNTCNGCNACNCCNGARGARMGNCAY YTNGCNAAYATGCARATGAAYGGNTAYGARAAYCCNACNTAYAARTAYTTYGAR------ CARAARGAYAARYTNTAYMGNCARATHACNGTNGARGTNAARGCNCAYGAYCCNGCNGTN YTNAAYAGYTAYCARAARTTYACNACNYTNGCNGCNGARCARYTNGGNGTNAARATHGAR AGYATHTCNGARCCNCCNAARGTNATHACNMGNMGNAGYYTNYTNAARTCNGTNTTYATH TTYAARAARCAYCARCAYCARTAYGARACNMGNACNYTNTTYMGNGTNTTYCARTTYAAR CAYYTNACNGARTCNACNGCNYTNACNTTYYTNGARTAYATHCARMGNAAYYTNCCNGAR GGNATGGCNATGAARGTNACNAARCAYGARATHCARCCNAARCCNGAYCAYYTNAARCCN CCNGTNCARTCN------------------------GAYTAYTTYAAYGTNATGYTNGGN TCNCARYTNYTNTAYAARTTYGARMGNCCNCARTAYGGNGARATHATGGCNGARCAYCCN GAYAARCCNATGTCNAGYATHTAYGGNGCNACNCAYYTNYTNMGNYTNTTYGTNMGNYTN GGNGCNATGYTNGCNTTYACNTCNYTNGAYGARMGNACNGTNCAYATHYTNYTNAAYCAY GTNCAYGAYTTYYTNAARTAYYTNTCNAARAAYGGNCCNACNYTNTTYAARACNTCNAAY TAYGARATHGCNACNCCNGAYTAYCAYMGNAARGCNATH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GTNCAYGCNYTNGCNAAYAAYCARGAYAARATHTCNTTYGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GAYCARAARCAYTTYMGNACNTTYATHAARNNNACNAARTCNYTNAGYGCNGARGAYAAR GCNAARAGYYTNGARGARGAYYTNGCNATGGGNGCNGCNCAYGARGARTCNGCNCARGAR GGNGAYACNTCNGCNCCNGCNGCNTCNGARAARGTNAARTGYCAYTTYGTNTCNYTNGTN CAYTTYAAYGGNGTNYTNGTNGARYTNGAYGGNMGNAARGARGGNCCNGTNAGYCAYGGN GCNACNACNGCNGAYACNTTYYTNGARGAYGCNGCNGTNGTNGTNAARAARTTYATHGAR MGNACNCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CCNAARGARTCNGAYTGYACNTGGAARTAYGTNAARGGN GARMGNAGYGARGCNAARAAYGTNACNGARTTYGAYCARAGYYTNAARAAYAGYATHAGY YTNYTNTCNAGYGAYCCNYTNGTNACNTAYCCNACNYTNACNGAYGTNTGGAAYMGNTTY YTNAGYTAYTTYGGNCARGTNGCNGGNATGATHAGYTAYGCNCCNGTNTTYMGNGAYTAY TAYGARCARGCNYTNAARGAYTTYTAYGAYGAYAAYATHATHTAYATHGARYTNMGNGGN YTNTTYMGNGGNGTNTAYGAYYTNGAYGGNACNGTNTAYTCNGCNGCNTCNATHYTNAAR YTNTAYATGCARGCNACNGARGAYTTYGTNAARGCNAAYCCNAAYTTYATHGGNACNAAR TTYATHGTNACNAGYACNMGNGAYGARCCNCARGCNTCNGTNATGAAYGARYTNAARACN ACNYTNGAYYTNMGNAARGARTTYGARTCNTGGGTNATHGGNTAYGAYYTNGTNGGNCAR GARGAYCCNAAYTAYTCNYTNYTNCAYTAYAARAAYGARYTNYTNGCNCCNAGYCARATG TCNCCNCCNAAYAGYYTNCCNTAYTTYTTYCAYTCNGCNGARACNAAYTGGCARGGNACN GARACNGAYTAYAAYYTNATHGAYGCNATHYTNYTNAAYACNACNMGNATHGGNCAYGGN TTYGGNYTNGTNAARCAYCCNAGYYTNGTNAARATGGTNAARGAYAARGGNATHGGNGTN GARGTNAAYCCNATHTCNAAYCARGTNYTNGGNYTNGTNAARGAYCCNMGNAAYCAYGCN ATGGTNCCNYTNATGGCNAAYAAYYTNCCNATHGTNGTNAGYTCNGAYGAYCCNGGNGTN TGGGARGCNGCNCCNYTNTCNAGYGAYTTYTTYATHGCNTTYATGGAYATGTGYGGNGAR GAYGCNGAYYTNMGNTTYYTNAARCARYTNGCNGCNAAYTCNYTNAARTAYAGYACNYTN AAYAARACNGAYATGGARMGNGCNATGGGNATHTGGACNCARCARTGGAAYAARTTYATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGARCARCAYTCNAGYATHYTNYTNGCNYTNATHTTYTCNYTNGTNTGYGTNAGYATH GTNACNTGYYTNCCNGCNMGNTCNGCNGARGAYATHYTNCARGAYGCNTCNGAYYTNGTN GTNGAYAARMGNCCNAARTAYATGGAYACNMGNMGNGARYTNGAYGTNTTYAARGAYYTN GTNTCNATGAGYATHCARGARYTNGTNGAYGARGGNMGNYTNGARTCNTCNATHYTNCCN CARGARGGNAARGAY------GCNACNAARCCNGTNGARAARMGNMGNTAYATGGGNYTN TGYATHCAYMGNCARGCNAAYCARTTYATHCCNTTYCCNTGYYTNMGNGCNGGNMGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGYYTNYTNGCNYTNGGN YTNYTNYTNATHYTNACNGARTCNAAYGTNTCNGCNGAYTAYGARCAYTAYTGYTAY--- CCNGAYTCNTCNATHGARACNMGNGGNGTNTGYGGNGAYCARYTNGTNGAYACNATHTAY ACNTAYTGYAAYYTNTTYGCNGGN------------ATGGGNAARTAYATHGTNAARMGN AGYMGNGCNCARGCNGAYAARGAY---YTNCAYGARYTNYTNGTNAAYAARAARGAYGCN TCNTCNTTYYTNTCNAARMGNCARACNACNCARAAYGTNGTNTGYGARTGYTGYGTNAAY MGNTGYTCNGTNGCNGARATHTAYCARTAYTGYCAYYTNCCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARTCNTTYGCNAARYTNAARAARAAYGGN---GGNAAR YTNGTNTAYGAYMGNGCNTAYYTNATGGARYTNMGNGGNTGYGTNTCNTCNCARATGAAR CCNGAYGGNYTNCCNGCNYTNGARGTNATHYTNGAYAARCCNGAYCCNACNATGTCNMGN YTNTCN---GGNGGNCCNGCNGAYTTYACNCCNGCNTTYTTYCARCARGGNACNAGY--- ---MGNCAYGCNCCNCCNATHGGNAARAGYAGYAGYMGNGGNMGNCCNMGNCCNGGNGAY ATGCCNTCNACNCCNMGNGTNATHAARAGYATHTCNATGTCNAGYGARGCNAARCCNYTN CAYCARGCNGAYAAYCCNTGGAAR---------CCNTCNAARAARGARACNAARACNGAR GCNMGNACNYTNGARGGNGAYATGYTNTTYATHATGAAYMGNYTNACNCCNACNAAYTTY GAYAARATGGCNACNGARATGAARGCNYTNGAYGTNAARACNTAYGARGAYYTNCARTAY ATGGTNAARGTNTTYTTYGAYAARGTNACNATHGARACNAARTTYGTNGARGCNTAYGCN CARYTNTGYAARGTNATGTCNTCNYTNMGNGTNGCNCCNCCNACNGAYGGNACNGTNAAR GARTCNATGGCNACNTTYMGNGTNGTNATGYTNACNAARTGYCARCARGARTTYGARGCN GAYAARTCNATHATHTTYGARGAYCCNGARGARAARAARAARAARYTNGARGCNGARAAY CCNGARAGYCCN---CARMGNGAYGARATGATHGARCARGTNYTNTAYAARATGAARYTN AARMGNATGAARTTYTAYGGNAAYATHMGNTTYATHGGNGARYTNTAYAARYTNGGNATG YTNACNGARAGYATHATGCAYGAYTGYATHTTYMGNYTNYTNAARGCNMGNGAYGAYGAY TCNYTNGTNTCNYTNTGYAAYYTNYTNACNACNGTNGGNMGNAAYYTNGAYACNGAYAAR GCNAARCCNMGNATGGAYCARTAYTTYTCNCARATGAGYAARATHGCNGARGARMGNAAR TCNMGNATHAARTTYACNYTNAARGAYGTNATHGAYYTNMGNCARCAYAAYTGGGTNCCN MGNAARGARGCNACNGGNCCNAARAARATHGAYGARGTNCAYAARGAYTTYGCNCARGAR CARGCNMGNAAYCARTAYYTNGCNTCNCARCCNYTNCCNCCNMGNAAYGAYAGYGCNCAR GCNGGNAGYMGNMGNGGNAGYMGNCARMGNCCNGAYGAR---MGNCCNAAYGARGAYGGN TGGAAYACNGTNAGYTCN---AARTCNGTNMGNATGATHGAYGCNTCNAARATGAARATH TCNAAR---AAYGTNGTNGAYGAYAAYATHCARYTNGGNCCNGGNGGNGGNGCNCAYMGN CARACNATHTGGAGYMGNGGNAGYCAYGGNGGNGCN---CARCCNTCNYTNGAYGAYMGN CARCCNGGNGGNTCNAAYMGNTTYTCNGCNYTNACNAGYGAYGAYACNMGNMGNTCNTTY CCNMGNTCNCCNTCNMGNGGNGARGGNTCNGCNGGNMGNAGYYTNMGNCARGGNCCNACN GCNGGNCAYGGNMGNGGNAARATHATGACNMGNTCNAGYCARGARGGNGARMGNMGNAGY GCNATHGCNAAYACNMGNTCNTTYATGGGNGGNMGNTCNCARAAYTCNAGYMGNGAYAAY AGYTGGAAYMGNGAYGAYMGNMGNCARYTNGTNGGNCCNMGNAGYTCNTGGGARMGNGAY AGYCCNATGAGYMGNAGYGAYAGYGCNGTNMGN---ACNGARGARTTYMGNGCNCCNGCN CCNCARCCNGCN---GTNAARCARATGAGYGARTCNGARATHGARACNAARGCNACNAAY YTNYTNGAYGARTAYYTNAAYATHMGNGAYYTNGCNGARGCNAARYTNTGYGTNAARGAR YTNAGYGGNCARAGYCAYATHCAYTTYATGGTNTTYGCNAGYATHAAYAAYGTNYTNGAR AARMGNGAYGARGCNMGNCAYATGACNGGNCARYTNTTYCAYGARYTNGTNCAYTGYAAY ATHYTNTCNGCNGAYATHTTYACNMGNGGNYTNAAYGCNGTNYTNGARTAYGCNGCNGAY ATGGTNGTNGAYATHCCNACNYTNTGGAAYTGYYTNGCNCARATHATHTGYCCNYTNYTN ATHGGNGGNTCNYTNCCNTGGCCNAARYTNAARCARGCNYTNACNCCNCAYYTNGAYAAY ATGGAYGGNGCNAARYTNYTNGCNGCNGTNGTNTCNYTNTGYGCNACNGARCARGGNGAR AARGARGTNGCNTAYCARTGGCARAAYAGYACNYTNAGYTGGAAYGCNTAYYTNAARCCN GAYGAYGTNAAYGAYTTYYTNAARAGYMGNAARGTNGARTTY---ACNACNATGATHTTY GARGGNGGNATGGARAARYTN------------------------------------GAY AARYTNGARGGNATGGTNCARTCNMGNAGYTCNATGCARGAYATGATHGCNTTYGTNGAR AARACNGTNCCNGGNAGYAARACNGAYCCNAGYTTYATHMGNGCNYTNACNACNGCNGTN GTNAGYGCNGCNATGACN---------GAYAARAARACNGTNGTNGARGAYGCNATHAAR CAYAGYAARGAYYTNYTNCARMGNTAYATH---GGNAAYAARGTNGAYYTNCARYTNCAR GCNYTNTAYGCNYTNCARGCNYTNATGGCNAARYTNGARCAYCCNTCNGGNGCNYTNTCN AARYTNTTYGARYTNTTYTAYTAYGARYTNTCNATGGARGAYGARGCNTTYTAYMGNTGG GARAARTGYGCNGAYCCNCARGARCARGARGGNAARGGNACNTGYYTNATGTCNGTNMGN CARTTYTTYATHTGGYTNMGNGARAAYGARGARCCNGAR---------GGNTTYGCNGGN GAYGTNGAYGAYATHGCNAGYACNGGNYTNGGNGCNCCNGCNGAYGGNCARGGNCAYTCN TTYACNYTNTTYGAYGGNGGNCARGARGTN---------------------TGGATGGAY GAYTTYGGNGGNYTNGGNGAYCCNYTNGGNGAYGAYAGYATGGARGCNTTYATHAAYYTN GAYACNTTYYTNAAYGGNAAYTCNTTYTTYGAYGAR------GAYGGNAAYYTNATH--- GTNCCNGAYAARGCNGARGTNYTNCCNGTNATHGCNCCNCARGCNGARGARCCNGCNYTN GTNCCNGTNGARGTNCCNCCNGCNAARAARACNAARTCNGCNGGNAARTCN--------- ---ACNACNMGNAARMGNAARGCN------CCNGCNGGNGCNGTNAARACNAGYYTNTAY GARATHCCNGAYTCN---------------GAYGGNGCNTCNGCNGCN------GGNTGY GCNGTNAGYGAYGCNAGYYTNGAYCAYGAYTAYAGYTCNAARMGNCAR------------ ---------------------------------------------------------MGN YTNGCNGTNCCNGGNTCNTGYAGYGAYGCNCARGARATHAGYTCNYTNCCNAGYACNTCN GGNGAYTTYYTNTCNTCNCCNGGNCCNGTNGAYAARCARACNATGMGNMGNATHAARAAY AAYCAYGCNTCNAARMGNTCNMGNGARCARMGNAARCARAARGTNATGGARATGGAYCAR GARGCNGARGARYTNGTNGTNMGNAAYCARGARYTNMGNNNNAARATHGTNGARYTNGAR AARYTNGCNAARGARATGAARGCNGCNYTNGTNGCNAARATGGCNGGNMGNGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AAYTCNTTYAAYATHMGNCCNTCNGTNTTYTCNGGNCCNTTYGAYTCNGGNTCNAAY MGNCCNGGNGCNCCNYTNYTNAARCCNGCNAARYTNCCNGAYCCNACNAARTCNTGYGAY GGNAAR---GAYTCNCCNAGYGARGCNGAR------GTNGTNACNCCNGARGCNAARCCN AGYGARGCNAGYTCNGTNAGYGAYMGNYTNGAYGCNGCNGAYGGNACNTCNGGNGCN--- GARGTNTCNTCNTCNTCNTCNACNTCNTCNTCNAAYYTNCCNCCNCCNTCNACNYTNCCN GAYACNGARGGNGCNGTNGGNGGNGARAAYACNCCNTAYAAYCARGAYATHGTNCCNGAY ATHAAYAARAAYAAYMGNYTNAARGAYTCNTCNGGNGTNTCNAGYAGYTCNCARTCNTTY GTNTTYGGNAGYAAYATHTCNCARMGNGCNACNGGNATHACNTCN---TCNCCNGTNGGN GGNGARGCNTCNCCNTCNTCNGGNTTYGTNTTYGGNGARTCNYTNAGYAGYMGNGCNGTN CCNGARACNAAYGGNTCNGCNCARTCNCAYAARGAYGAYGARAGYGAYTCNGAYTCNGGN AAYAARYTNAAYCARACNYTNGARGARTCNGCNMGNGARTAYCARGCNAARCAYGAYACN MGNACNGARYTNAARGARGTNGARACNATHACNGGNGARGARGARGARTCNAAYGTNYTN AARGCNAAYGCNAARYTNTTYTTYTTYGARACNMGNAAYGARTCNTGGATHGARMGNGGN MGNGGNACNATHMGNYTNAAYGAYATGTCNGCNMGNGAYCARACNAAYTTYCARTCNMGN YTNGTNATGMGNACNCARGGNAGYYTNMGNGTNGTNYTNAAYGCNAARATHTGGCCNGGN ATGTCNYTNGARMGNGCNTCNCCNAARTCNATHMGNATHACNGCNATGGAYACNGAYGAR TCNATHMGNATHTTYYTNATHACNACNACNGCNAARGAYTCNGARAAYYTNYTNMGNGCN ATHGAYTGGMGNATHCARCARYTNAARATHCARGARGARCCNGCNMGNCARCAYTCNGAY GCNMGNACNGGNGAYAARMGNAARGCNGAYGAYTCNGAYTTYGARYTNCCNNNNAARGCN AARAARATGAAYAGYCCNTCNGAYCARGGNATHTCNATHACNAARAARGARGARTCNGAY AGYAGYGTNCARGAYCCNGARACNGARGCNTCNTGYGARAGYCAYTCNTCNTCNYTNACN ATHAARTCNGARTCNGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNTAYAARYTNGARGTNGARAAYCCNCAYCARCCNATG MGNACNYTNACNGAYATHATGAAYTTYTTYGTNYTNACNTCNAGYGCNYTNACNACNAAR CCNATGACNTGYAAYCAYYTNCCNCARTTYGGNATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGCNTCNTCN AAYYTNTCNMGNTCNGTNYTNAARTCNYTNCARTCNMGNTCNTTY---GCNGCNGCNGCN CCNCARGCNGARMGNYTNCARACNGAYAAYCAR------MGNTGYTCNGTNAARAARYTN AARAAYGGNATGCAYGTNGGNGTNATHCAYTCNAAYTCNCCNGTNTCNMGNYTNGCNGTN GTNACNAAYGCNGGNTCNMGNTTYGARAGYGGNGAYAAYYTNGGNATHTCNCAYTTYYTN MGNATGTCNTCNMGNYTNMGNACNGARAAYATGACNAGYYTNGGNYTNACNMGNACNGCN CARCARYTNGGNGGNGAYGTNACNATHATGGGNTCNMGNGARTAYATHCAYTTYAARAGY GGNGTNACNMGNAAYGTNGCNGAYAARATGGTNGCNYTNYTNCARGARYTNACNACNMGN CARGTNTAYACNCCNTGGGARGTNTCNGAYGTNCARCARAGYAARGAYGGNATGYTNYTN GAYYTNGCNYTNTAYCARACNMGNCCNCAYGTNMGNGCNGTNGARYTNYTNCAYTCNGCN GCNTTYMGNAAYACNYTNGGNAAYTCNYTNTAYGCNCCNGAYCAYATGGTNGGNAARTAY ACNCCNGARCARGTNATGCARTAYGTNAARACNCAYTTYAGYGTNGGNMGNATGGCNYTN GTNGGNATHGGNGTNGAYGARGCNYTNYTNGARGARYTNGCNGCNGAYTTYGARCCNTAY GCNTCNGCNGGNGTNCCNGTNGARAARTCNTCNTAYTAY---GGNGGNGARYTNMGNGAR AGYACNGGNGGNAAYATHTCNTAYGTNGCNGTNGGNTAYGGNGGNCCNAGYYTNACNAGY AARGAYYTNYTNGCNGCNGARGTNYTNMGNCAYATHYTNGGNACNGGNCCNCAYATHAAR TAYAGYAGYGGNAAYTCNGTNGCNCAYYTNCCNAARTCNGCNTCNCARGCNACNGARGCN CCNTTYCAYGTNTCNTGYYTNAAYGCNACNTAYACNGAYAAYGGNYTNTTYGGNTTYACN GCNGTNGCNCAYGCNTCNCARATHGARAARGTNGTNCARGCNGCNTCNGGNCARYTNAAR TCN------GCNGCNAAYGTNACNGAYCARGAYGTNGTNMGNGGNAARAAYCARYTNAAR GCNGARYTNTGYATGCARTTYGARAAYCCNGAYGTNYTNYTNAAYTGGYTNGGNGARCAR GCNYTNAAYGGNGARGARGTNGTNACNCCNGARGAYATHTAYAARATGGTNGAYAGYGTN AAYACNAAYCARGTNAAYCARGTNGCNAARAGYATHYTNAGYTCNCCNCCNTCNATGGCN ACNACNGGNAAYACNTCNAAYGTNCCNTAYYTNGAYAARYTNATGGGNGCNAARGGNAGY AARCARAARAGYAARAARAGYAARAARGGNGARGARGARGCNGGNAAYGARGARGCNCAR GARCARCARCCNGARACNACNGARGGN------TCNGARCARAARGAYAARGCNGARGGN AAYGGNGARGCNGCNAARATHGARAAYGGNGAY------GTNAARGARGCNAARAGYGAY GARACNACNGCNGCNGAYCCNTCNGARCCNGCNAARGARGARGARAARCCNTCNGARGAR GTNCCNGCNAARTCNGARCCNGARCCNGCNGCNCCNGCNGARCCNGCNGCNAGYGARGAR CCNGTNTCNGARCCNGCNGCNGARGARGARCCNGCNCCNGCNGCNGCNGCNCCNACNCAR GARGARAARCCNGARGARGCNCCNGCNGCNGARGARGARAARAARGARGARGARCCNGCN CCNAARGARGARGARCCNGCNAARGAR---GARGARCARAARCCNGARCCNGTNGCNGCN CCNGTNGARCCNTCNGCNCCNGTNGARGARCCNTCNGCNCCNGTNGARGARGCNCCNGCN CCN------------------------GTNGARGARACNCCNGCNCCNGCNCCNGARCCN GCNGCNGARGARAARAARGARGCNGCNCCNGARGCNCCNAGYGCNGARGAR--------- ---------------GCNGCNCCNGCNGARCARGTNYTNACNMGNAARAARACNATHCCN AARYTNGCNCARACNGTNAARGCNGCNMGNGGNATHYTNCARTTYTCNTCNTCNAARGAY AARGARAGYCARAAYGCNAGYGAR---GARAGYGCNCCNGCNACNCCNTCNGARACNGCN GARACNGGNGCNGCN---------GAYGGNTCNGCNGCNGARACNGGNGARACNGCNGCN CCNAGYCARGARTCNGCNCARTCNACNGTNMGNACNGARTTYAARTGGGARAAYGGNGGN GARACNGTNYTNGTNAGYGGNAGYTTYAAYAGYTGGGGNGARAARATHGCNYTNTCNAAR GARGGNGAYATHTTYACNGGNTTYATGGAYYTNCCNGTNGGNGARTAYYTNTGYAARTTY ATHGTNGAYGARGARTGGGTNGTNAAYAARAAYYTNCCNATHMGNGCNAGYGARGAYGGN CARGARAAYAAYGTNATHYTNGTN------------------CAYTAYACNATHGTNGGN YTNGTNTTYATHYTNGCNTTYACNGTNGTNGGNAAYTTYCARYTNTTYGTNTCNAARCAR TCNYTNAAYTAYTGGGAYGARGAYTCNACNATHATHGGNTGYTTYYTNTGGGAYYTNGCN YTNYTNTGYYTNTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TGYAARAARTAYTCNTCNYTNACNGCNGARGCNAAYGAYATHCARATGGARAGYTAY AAYACNATHMGNMGNGCNTCNGCNTGYYTNMGNCAYATGTCNCARAAYMGNGARACNCCN ---------------GTNGAY---TCNATGACNYTNGAYMGNTCNTAYMGNMGNGCNMGN MGNGCNMGNGAYTCNTGYCAYTCNGCNCCNGGNACNYTNCARMGNCARCAYMGNAAYMGN CAYTCNGGNGGNCARAARCCNCCNGCNCCNCCNAGY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARGARAAYGARTAYATH AARAARYTNGAYCARCARATHGAYGAYYTNGARAAYGARAARATHGCNYTNGGNYTNCAR GTNAARGARYTNAAYGARAAYYTNCARGAYGARAARGARTCNMGNCARCARYTNAARGAR AARTTYGARYTNYTNAARGARGARYTNMGNCARACNAARYTNGTNGTNAAYAAYCARGAR GAYYTNYTNCARCARGTNGCNTCNACNTCNGARAARGTNTAYGARCARTAYAAYAAYATG GARGARACNTAYMGNCARGARGTNGCNYTNMGNAGYGARGTNGARMGNGARGCNCAYAAR YTNTCNAGYCARMGNGAYCARGCNMGNMGNGARAGYGCNATGGCNYTNAGYAARGTNGCN GAYAAYAARAARYTNATGGAYGCNATGYTNCARATHCARGARYTNAAYACNCARTGYACN GARATHAARGCNGAYTAYGARMGNAARATHGARGGNYTNGARAAYCARYTNGARGCNGCN AARGARGTNTAYAAYGCNGARAGYYTNCARGAYGARAAY--------------------- AAYGARYTNCARGARAARTTYGARGCNAGYGARGCNGARGTNAARMGNYTNCAYACNCAR GTNACNGARATGACNGCNAARTAYAARACNYTNGARGCNAARTAYGARCARGCNACNAAR ATHYTNYTNCCNCCNCCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYGCNAGYGAYATHAGYTTYYTNGAYCCNATHAAYCCNGCN YTNGTNGCNYTNACNAAYCARGTNGAYAAYTCNYTNMGNATHAAYGTNYTNCCNGGNCAR YTNTCNCARCCNATGTCNGTNGARGARAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AARATGAARMGN TCNGARMGNCAYATGATGMGNYTNAARAGYATHATHTCNMGNGTNYTNAARGARAARGGN GTNGARGARGGNGAYCCNATHTAYGAYGCNTGYTTYAARAAYYTNYTNAAYGTNAGYATH GTNYTNYTNAARGCNYTNCCNAAYTCNCARAAYYTNACNGAYGARATGAARTCNGTNGTN TAYGGNCARGTNCARCARATHATHAAYYTNGARAARMGNMGNTGYGGNATHGCNATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TTYTAYTAYTCNCAYMGNMGNAARMGNAGYMGNAGY AARGAYMGN------AARMGNTCNMGNAGYAARGAYMGNMGNTCNMGNAGYAARAGYAAR GAYMGNMGNAARMGNGAYMGNGARMGNAGY------------------MGNMGNMGNAGY MGNAGYMGNGAYMGNMGNMGNAGYAARAGYMGNAGYMGNGAYMGNMGNMGNAGYMGNAGY TGGAGYMGNGAY------MGNMGNMGNMGNAGYMGNTCNCCNMGNMGNMGNAGYMGNAGY CCNGGNCAYMGN---GARMGNYTNCCNGARYTNACNGTNGARGARMGNGAYGTNMGNACN ATHTTYTGYATGCARYTNTCNGCNMGNATHMGNCCNMGNGAYYTNGARGARTTYTTYTCN TCNGTNGGNAARGTNMGNGAYGTNMGNYTNATHACNGAYAAYAARACNMGNAARTCNAAR GGNATHGCNTAYGTNGARTTYGCNGAYCCNGARTCNGTNACNYTNGCNATHGCNYTNACN GGNCARAARYTNYTNGGNGTNCCNATHYTNGTNCARCARTCNCARGCNGARAARAAYMGN GCNCCNCCNGCNACN---TCNGCNCARGCNCARAARCCNGTNCCNGARGGNCCNYTNMGN YTNTAYGTNGGNTCNYTNCAYTTYAAYATHAAYGARGAYATGYTNMGNGGNATHTTYGAR CCNTTYGGNAARATHGTNGAYATHAARATHATGMGNGAYCARGAYACNMGNMGNTCNYTN GGNTTYGGNTTYATHAGYTTYTCNAAYGCNGAYGAYGCNAARAARGCNYTNGAYCARYTN AAYGGNTTYGARYTNGCNGGNMGNCCNATGAARGTNGGNCAYGTNACNGARMGNTCNGGN GARGGNGGNCARGCN------GCNCARAAYGGNGTNGGNGGNCARYTNGAYACNGAYGAR ATGGAYMGNGCNGGNATHGAYYTNGGNGCNACNGGNMGNYTNCARYTNATGGCNAARYTN GCNGARGGNACNGGNTTYCARATHCCNCARTAYGCNGCNAGYGCNYTNAAYAGYATGTCN ------------ACNCCNGCNGCNACNCCNGGNYTNCCNGCNGCNGCNCCNCCNGTNGCN AAYAAYGTNGCNCCNGCNATHCCNACNACNGTNGCNGCNCARCCN------------ACN GCNACNGTNACNAAYGCNCCNCCNATHGCNACNCARTGYTTYATGYTNTCNAAYATGTTY GAYCCNACNTCNGARCCNMGNYTNACNTGGGAYCARGARGTNMGNGAYGAYGTNATHGAY GARTGYAAYAARCAYGGNGGNGTNYTNCAYATHTAYGTNGAYAARAAYTCNCCNCARGGN AAYGTNTAYGTNAARTGYCCNAGYATHTCNGCNGCNGTNGCNTCNGTNAAYTCNYTNCAY GGNMGNTAYTTYGCNGGNMGNGTNATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CCNCCNYTNAAYGCNACNACNTAYMGNGAYGTNATHGGNGARTCNTCNAARACNATH AARAARYTNGARTCNGGNTTYCARGARATGTAYYTNAARAGYTAYAARGAYAGYCARMGN TTYATGAARCARCARCARAARATGYTNMGNGARCAYATGMGNAARCARTCNGCNYTNYTN GCNAAYGARAARGARGTNAARGTNYTNTGYGAYYTNATHATHYTNGARCARMGNAARAGY CARGAYTCNGTNTCNGCNGGNGCNAGYGCNGCNATHGARGCNGCNYTNATGTCNCARGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CAYGCNMGNCCNTGYATHCARTGYTCN CAYGGNMGNTGYACNACNGCNTTYCAYGTNTCNTGYGCNTTYYTNGCNGGNATHAARTTY GARATGTGYGAYTGGCCNGTNCCNATHTAYGTNTCNTGYMGNAARCAYACNGCNACNMGN AARAARGCNGARACNMGNGARGAYATGGCNGAYTTYGAYATHGGNTGYGTNACNYTNGCN AARCAYMGNAAYAARMGNTTYTAYTGGGCNAARGTNGTNMGNGTNGAYMGNAARAARYTN TAYGARGTNGAYTTYGAYGAYGGNTCNTAYAGYGAYGAYYTNYTNCCNGARGAYATHGAR AGYGTNGAYTGYGTNMGNGGNGGNCCNCCNCARAARGGNCARCAYATHTCNATHAARTGG GARGAYGGNACNYTNTAYGGNGCNACNTTYMGNMGNGTNAAYAAYCARGAYYTNTAYACN GTNGARTTYGARGAYGGNTCNCARYTNCARGCNAARMGNGARGARYTNTGGGGNGARAGY GARGARATHCCNMGNCAYATHMGNAAYMGNATGAGYCARGCNACNGARCARAARTTYGAY YTNTTYGAYGARGAR---GCNCARGAYGGNMGNMGNAAYAARAARAARGTNAAYTAYYTN AARATGYTNGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGCNTCNCCNGARGTNAARGARYTN YTNACNMGNCAYAARTCNYTNGTNTTYGAYCARGARACNCARAARATHAARTGYAAYYTN ACNAAYCAYGARATGCCNGCNAARGTNGCNGCNATHGARAGYTAYGTNAGYGGNAARAAR TAYMGNMGNYTNGCNCARYTNGAYGAYYTNTCNTAYGARGAYCAYAARATGCAYATHGTN CCNAGYAGYAARAARGAY------AAYGARATGTTYTGYMGNYTNACNATHMGNCAYYTN GARAARACNGCNAARGCNATHCARMGNCAYATHAAYGGNMGNAARTAYAARAAYGCNYTN GCNMGNTGGAAYGARTGYAARCARACNGGNAARAARTTYGTNGCNCAYATH---MGNMGN GCNAARAARTCNCCNGARTCNGAYGARGAYAAYGAYGGNAARGTNGAYGARCCNAGYGAY GAYTGYATHATHGAYGAYGAYGAYGAYGAYGAYATGAGYGAYYTNTAYCCNGARGCNGAY TTYCAR------GAYTCNGAYGAYGCNGARGGNGAYGAYAAYGAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHATGAAYATHGARCCNGAYAAYGTNYTNTGGAARMGNGAR MGNCCNTCNCAYCAYGCNGGNGCNYTNMGNAGYTAYATHAARGAYCAYGAYGAYAAYAGY YTNCCNMGNGGNCCNGAYGCNAGYCCNYTNTTYTGYCCNGARTGYGAYYTNGCNGAYAGY CARTAYGAYTCNGCNAGYCCNAAYAGYYTNACNTGGYTNATHTCNCCN---GAYAAYTCN CCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGACNGAYAGY CAYMGNATGTTYYTNCARAGYTTYATHTCNAARGGNGTNATGAAYACNMGNGARATHAAR GARAGYTAYATHYTNAGYAARAAYMGNTTYGARGAYGCNMGNGGNGARATH--------- ------ATHTCNGAR---------------TTYGTNMGNACNATHAAYYTNGCNATHTCN CCNTTYAAYYTNGARATHAARAARGGNTAYCARGARCAYGAYGGNTCNAGYGTNTAYTGY YTNGTNAAYACNGTNGARTCNGCNATHTCNAARYTNTCNTCNACNTAYACNCARAARGAR YTNGARYTNTTYAARAARGTNATHGAYTTYATHGTNGARTCNGAYAAYGGNAARATHGGN TCNATGATHGCNYTNAAYYTNACNGARAARYTNGARAARAARATGGGNAARGARGARGCN CARAAYTTYTTYAAYAGYYTNGARMGNGARGARTGGATHGTNAARGAYACNGAYGGNAAR ATHTCNYTNTCNGTNMGNACNYTNYTNGARYTNGAYCARTAYYTNCARGAYATGTAYTCN GARYTNGTNAARAARTGYAAYATHTGYGCNAARATHTGYYTNCARGGNGARACNTGY--- GGNTGYGGNATHAARATHCAYTTYATGTGYYTNAARAAYYTNTTYTCNMGNCARACN--- GARAARAARTGYCCNAGY------TGYMGNGCNTCNTGGGGNGAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARAAYTTYMGNTAYGTNYTNGARATHYTNACNAARTGYYTNMGNAARMGN CCNGAYYTNTCNAARGCNGARYTNGAYYTNATGYTNACNGTNATHGCNAARGTNTCNTTY GAYAARATGTTYCARGAYGGN---TTYCARMGNACNTTYCARTCNYTNGTNTCNTCNATH YTNGAYTGYTAYAGYGARTCNGAYTGGCCNTCNGTNGTNYTNTCNYTNTGYCAYCARYTN AGYACNATHATHCARCAYCAYCAYCARGCNGTNTAYYTNTCNGGNYTNATGCCNTGYAGY GTNMGNGGNAAYTAYYTNCARMGNMGNYTNAGYTTYYTNYTNYTNTGYTCNATHYTNGAR CCNGAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GTNGAYYTNGCNGGNTCNGARMGNYTNAGY AARACNAARTCNGARGGNAARACNAARCARGARGCNATGTAYATHAAYAARTCNYTNTCN TTYYTNGARCARGTNGTNATHGCNYTNGCNTCNAARACNMGNGARCAYGTNCCNTTYMGN CARTCNAARYTNACNCAYTTYYTNAARGAYTCNATHMGNGGNAAYTGYAAYACNYTNYTN GTNGCNAAYATGTGGGCNGARAARYTNCARYTNGARGARACNGTNTCNACNYTNMGNTTY GCNACNMGNATGATGTGYGTNGCNAGYGARCCNGCNGTNAAYGARATHTAYGAYCCNGCN YTNYTNGTNAARAARNNNCARMGNGARATHACNCAYYTNAARTCNGARYTNGCNATGCAY GAYACNYTNACNAAYMGNAGYATGATHTCNTAYGAYCCNYTNTCNGARCARCARAARTAY GARATH------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CCNATHCCNCARCAYGCNGARAAYYTNCARAARYTNYTNCARAGYTGYGTN AARGAYCARGAYTGGATHAARGARYTNCAYTAYTCNGTNATHACNAAR---AARYTNGTN ATHMGNYTNAARGAYCAYATHCAYMGN---NNNYTNGARAGYATHAARYTNAAYGCNAAY CARYTNATGGAYGCNGARCCNTCNGGNATGGTNAARGGNGTNGGNATGACNATHAARGGN AGYCARGAYAAYGGNTGYATGGAYGARCARGGNAAYGTNTAYGAYTTYGTNTCNMGNTAY TTYGCNCCNTGGYTNGGNATHCCNGARGAYCCNGTNACNGGNTCNTGGCAYACNGTNGTN GCNTCNTAYTGGGCNAARGARYTNGAYAARTCNCAYYTNTAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARGAR GARGARGARGARGARGARAARCCN------AARGTNMGNAARCCNAARAAYCCNGAYYTN MGNCAYAAYGCNGAYGAYGAYGARATGMGNTTYACNGGNYTNCAYTCNAARACNGAYATH CCNTCNMGNACNTTYGAYMGNATHAARAARTCNACNCCNGAR------------------ ---ACNGARCARAAYGCNYTNGCNGTNGARGAYAAYACNGAYGGNGTNGGNGAYTAYAAY GARGCNTCNATHMGNTAYGTNGGNAARAAYATHCCNTCNCCNGCNTTYMGNGTNYTNCAR ACNTGGGCNGARAAYGAYCCNGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYAARTGYATHGARATGMGNACNGAY MGNCCNTGGACNTTYCARACNGAYYTNTTYGGNYTNGCNGGNACNATHCAYGTNYTNYTN TTYGGNGCNTAYATGAARGTNTAYCCNGARAAYGGNGARTGGAARGCNACNGCNAGYTTY GCNMGNAARTGGAAYGTNTCNYTNTGGAARMGNYTNTTYMGNCARYTNYTNAAYGTNCCN TCNTGYGARTCNATGCCNGAYYTNGGNGGNYTNMGNGCNGARTTYGARGAYTAYTTYTGY TCNAGY---YTNGTNTCNTAYAAYGGNTGGGTNGCNAARGTNCAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARAARGTNCCNCCNGGNATHGAYATHTAY CCNATHTCNGCNTTYAARYTNGAYAGYACNTTYTAYGTNGARCCNCCNCCNATHAGYMGN CARGCNAARGAYATHTAYACNGCNTAYGTNAAYMGNGGNCAYCARGGNGCNCARTCNGTN TCNGAYGARAAYMGNCAYGCNTAYATHMGNTAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AGYCARMGN AARCARTGGGGNCARCCNAGYGAYATHAARYTNAAYGCNTCNGGNCARYTNGAYACNGAY GCNGTNATHMGNMGNGTNCARCARAARCAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GCNACNTCNYTNAGY AAYAARGCNAAYGARGARTAYGTNGARGARAAYTAYCARAARGCNATHGAYYTNTAYACN GARGCNYTNGGNGTNGAYGAYAARMGNGAYGAYATHTAYTGYTTYMGNGCNCARGCNCAY YTNGCNYTNGGNAAYTCNCARGCNGCNYTNAARGAYTGYGAYGARGCNYTNAARYTNAAY AARAAYAAYCARAARGCNTAYATHAARAARGGNTCNATHYTNYTNAARATGGAYGAYGTN YTNATGGCNCARAAYGTNTTYAARGARGGNCAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TCNGTNGCNTCNGCNAARAARGCNAARGARGARCCNGTNAAR AARGCNGCNMGNGGNMGNGGNMGNCCNCCNYTNTCNGCNGARGARAARGCNAARMGNYTN GARGCNAARAARTCNTCNAGYGGNMGNGGNMGNGGNMGNCCNAARGGNTCNACNAARCAR GCNAARAARGGNAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATHCAYGARCAYYTNAGY TCNAARGGNYTNTAYGARTCNGCNTGYGCNYTNCARMGNGARGCNAGYYTNCCNAARTGY TCNACNCCNCCNCCNCAR---TAYCCNAGYACNCCNAARACNMGNMGNCARYTNAGYCAY CCNAAYGGNTTYTCNGGNTCN------TTYGGNTCNAGYCCNTCNACNTCNACNCAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MGNYTNCARCCNATHGCNCCNAARGTNTCNAGY CCNGGNAARTCNGTNCCNTAYATHCCNYTNCCNMGNGTNAGYCCNAARMGNAARGARYTN AAYMGNCARGTNMGNCAYATHYTNCCNAARTCNTTYGTNTTYGARACNAARAGYCCNTCN CCNACNAARACNACNGCNYTNAAYYTNAARAARMGNGCNACNYTNYTNTGYCARAARAGY CCNGTNAARATHYTNCCNMGNTCNCARTCNACNCCNGCNGGNGARAGYGARACNAARGCN GGNACNCARACNATGATGTTYACNMGNTCNCARMGNGTNMGNAAYAARGCN--------- ---------------------------AARAARACNGARGARCCNGTNCAYAARGCNGTN AARMGNGTNAARAARATHGARGARGAYTTYGARAGYGCNAARGARACNGARAGYGARGCN AGYGARGTNGARGARTCNGGNYTNTCNCARGARGARGAYGAY------GAYYTNYTNAAR YTNAAYGAYYTNATGGCNGCNAGYACNACNATHMGNTTYGGNTCNAARCARAAYACNGTN GTNGAYGAYGAYGGNAARACNAARGCNGARAARAARAARGCNATGTCNYTNTCNYTNYTN CARCCNGAYYTNGTNCARTCNGAYCCNAARAARGAYGAYMGNGAYACNGCNTTYGCNCAR CARTAYTTYAAYCARGTNAARGARACNYTNTCNTCNGAYCCNGARMGNTTYTAYAARTTY YTNTCNYTNYTNAARGAYYTNAAYAARGAYCAYACNAGYCCNGTNGARYTNTAYYTNGAY ATGGTNTCNYTNYTNTCNGAYCAYCARMGNYTNGTNGARGAYTTYGCNGGNTTYYTNYTN TCNTTYCARGCNGTNGARTGYAARTGYTTYTCNACNAAYTTYCARTAYGCNCARATHMGN CARTTYYTNMGNCARGTNGARACNCAYTGYGGNTCNTCNACNAAY---ACNTAYCARAAR GTNYTNMGNGCNATGTCNACNTGGTCNAGYATGTGYCARGARGGNAARYTNGAYGCNAGY TTYMGNGAYAARATHTCNGCNATHYTNAARAAYGTNCCNGGNGTNYTNGAYAAYYTNATH GGNTAYTTYYTNGAYGGNAGYATHTCNGAYTGYCAYTCNATGGARTTYGARGAYGTNTGY YTNGAY---------GARGARGGNGAYGAYGCNGAYGARTTYGAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATGTCNAARMGNGGNCCNCARTCNGARYTNACNGAYMGNAAYTGGGAYAAYGAR GARGARCCNGARGAYCCNGGNGTNTTYGTNCARGCNTCNAARGARACNATHCARCARMGN GTNATHAARAARGCNAARMGNMGN------GGNGARGARGGNGGNGCNAARACNGCNTTY GGNGGNTTYGCNGGNTTY---------GGNAARGCNCCNGAYGCNAGYAAYACNGARGAR AARTCNYTNGGNAGYGAYTCNYTNCAYAGY---AARACNAAYTCNTCNGGNGGNGCNACN TCNTCNGTNGARAAYGTNGARTCNTCNAAR---------ACNGAYTCNAARGARAAYTCN GCNTAYYTNGTNGGNYTNAARTCNYTNAAYGARTGYGTNYTNGCNTGGATHAARCARCAY GTNGAYAAYAAYCCNTAYATHATHYTNACNCCNATHTTYAARGAYTAYGARAARTAYTAY GCNAAYYTNCARGCNAARAARCARATHGCNTCNAAYGGNGCNAGYTCNGTNTTYGCNGAY CAYGCNAAYGCNATGAARGCNGGNGGNCARGCNTTYGGNGCNACNTTYTCNTCNGAYGGN GCNGAYGCNAARAARGGNGGNCARGARGARGARAARCCNGCNTCNAARCCNGGNGCNGTN ACNTCNAAYGGNGARGGNTTYAARTTYTCNTCNTCNGCNCCNAGYAGYTCNGGNTTYACN TTYGGNAARACNTCNACNGCNTCN------TCNGGNTTYTCNTTY---------GCNCAR AGYAGYTCNGCNTCNTCNGCNCCNGCNACNACNACNACNACNGCNGCNTCNACNGGN--- ------------------TTYTCNTTYGGNGGNAAR------------GCNTCNACNACN ACNACNTCNGGNTTYGGNAGYTCNGGNTTYTCNTTYGGNGCNYTNGCNGCNAARACNATG ------GCNCARGGNGCNGARAGYTCNTCNAGYCAR---GCNGAYGGNGAYGARGARTAY GTNCCNCCNAARATHGARGTNAARGARATHAARGARGARGGNTCNYTNYTNTCNMGNMGN TGYAARYTNTTYTAYCARAARGARGGNGGNTGGACNGARMGNGGNYTNGGNAAYATHCAY YTNAARCCNATGGAYAGYAAYAARACNCARATHYTNGTNMGNGCNGAYACNAAYYTNGGN AAYATHYTNYTNAAYATHTCNYTNACNTCNGGNYTNCCNGTNTCNMGNCARGGNAARAAY AAYATHYTNYTNGTNTGYGTNCCNAAYCCNCCNYTN---------------AARGGNCAR GARGARGARACNCCNATHCCNATGYTNATHMGNGTNAARAGYGGNGARGARGCNGAYGAR YTNYTNGCNAARYTNGARGARMGNAARGCNYTNYTN------------------------ ---------------------CCNGARGCNMGNYTNMGNTCNGAYGCNGCNMGNGAYAAY GCNYTNAARAAYMGNGGNTCNGTNGGNGARAGYATGGGNGGNTAYGCNAAYCCNAARYTN GAYMGNCCNATHCAYCCNMGNGGNGTNMGNCCNGARGCNGARGCNAAYGCNTTYAGYAGY ACNGGNGGNAAYATGAARAAYYTNATGGARAAYTAYGGNAAYYTNTCNYTNTCNCCNAAR MGNGARCCNAARGTNAARGGNTCNGARGCNCARGARTAYAARGARMGNGARCARGGNAGY ACNAARYTNYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNGCNCCNCCNATGGCNTCNATHGTNGTNGARMGN CAYCARCCNGTNACNAARCARACNGTNGGNAARGCNACNGCNATHMGNTAYCCNAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GGNYTNAARGTNGTNATHCCNGAYMGNGGNCCNACNGTNAGYCARGCNAARATHCAR--- GGNACNGCNYTNGAYACNCCNAGYGTNTCNATHGCNACNCCNAAYAGYCARCAYGCNGCN CARGGNGCNATHCARGCNATHYTNCARTCNGGNGARYTNYTNAAYAGYGCNGAYATHACN GGNYTNTCNCCNYTNGTNTAYCAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGAGYTCN GAYGCNTGYTAYAARTGYGGNGGNMGNGGNCAYTTYGCNMGNGAYTGYMGNAAYGGN--- ---------------------------GGNGGNGTNCCNATGCARCCNTTYATGAAYGGN TTYACNACNCARAARTGYTAYAARTGYAGYMGNGTNGGNCAYTTYGCNMGNGARTGYACN CARGAYCARGARMGNTGYTAYAARTGYAAYGGNYTNGGNCAYATHGCNAARGAYTGYGAR AARCCNATHTCN---ACNGGNGCNTGYTAYAAYTGYGGNAGYGARAARCAYYTNCARMGN GAYTGYCCNCARGCNGTNGTNAARTCNTGYTTYMGNTGYAAYGARTCNGGNCAYYTNGCN AARGAYTGYCCNYTNGAYGCNGGN------------AAYAARCCNTTYATGGAYGAYMGN AARTGYTAYACNTGYGGNGGNATHGGNCAYYTNGCNAARGARTGYCCNACNCCN------ ------MGNAARGARTGYTAYMGNTGYAAYCARCCNGGNCAYGTNCARAARGAYTGYCCN AAYGTN---CARTCNACNACNCARTGYTAYAAYTGYAAYGARATGGGNCAYATGGCNMGN GAYTGYACNGCNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CCNGCNTCNCCNGAYGTNGAYATHAARGTNGGNGCNACNCCNAGYAARGARAARAARGAY AARAARGCNGTNAARAARGGNGCNTCNGCNACNGAYGAYYTNCARGGNACNGARAGYCCN YTNCCNCCNCARGAYYTNGAYGARAARYTNATHTAYGAYGGNTTYACNTTYGCNGTNAAY GGNATHAAYCARYTNATHCARGCNGARATGCARGCNMGNGARGCNGARGARGARGCNGCN MGNYTNMGNGARCARGARAARGARMGNGARAARGARAARGCNAARGGNGCNAARGCNGCN AARGGNGGNAARAARGGNAARAGYMGNAGYCCNTCNCCNAARAAR---GGNAARGGNAAR GARTCNGARACNTCNGCNACNCCNCCNCCNGCNCCNTCNGARGTNAGYGARGARGAYCAR CARAARAARTCNTCNAARGARMGNGGNMGNGAYGARTAYTAYTTYTCNATHCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GTNGGN AARYTNMGNCCNYTNGCN---GTNAGYATHYTNGGNAARTCNMGNMGNTCNYTNYTNCAY ACNACNMGNAARTCNGGNGARGCNYTNTAYMGNGARAARATGTAYGARTAY------AAR GARCCNAARTAYATHCARATHGCNGGNACNGCNTTYAGYGCNTTYATGTGGTAYTGGATH YTNTAYCAYTGYTAYTTYGARTTYGARCAYYTNGTNNNNGTNATGTCNACNYTNACNCAR GCNAAYATHCARATGAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAY GARTTYGCNTGYAARAARYTNGAYGARYTNGARACNAARTAYCCNGCNATHAARCARCCN ACNGARCARYTNAARGARACNTGYGTNGARTAYGCNGARCCNGTNATHGCNMGNGTNAAR CCNGTNGTNTCNCARGTNAAYGGNATGGTNGAYAGYGGNAARCARAARATHGCNAAYATH AARAARGCNAGYAGYGAYATGGTNGARGGNGCNAARAAYYTNGGNGTNGGNACNGTNTCN CAYGTNTTYAAYTCNACNTTYGARACNGCNCCNGGNMGNTTYGTNACNMGNACNGCNGAY GGNATGYTNGAYATGGCNGARGGNYTNGTNGAYACNTAYYTNCCNGARGARGARGARGGN GCNAARAGYAAYAARGAYAAYGAYGGNACNAAYGARAAY--------------------- ---------AARGAYGTNGARGARATGCARGTNATGGAYGCNACNCCNGGNMGNGTNATG GTNCAYGCNGGNTGYGTNACNCARAARYTNMGNAARMGNATGTTYMGNYTNGCNATGAAR GAYYTNACNTAYGCNAARGCNMGNGCNACNTCNGCNYTNAARCARYTNGARAGYACNGTN TAYYTNATHGAYTAYGCNAARGARAAYYTNACNACNGCNAARGAYAARGTNGAYAGYATG TGGACNGARATHGTNAARGAR------------ACNGTNGARGCNGAYGARAARACNGTN TTYGTNGGNACNATHGARGAYMGNATHGTNGCNYTNGGNMGNYTNGTNGCNMGNCARGTN MGNTCNGGNGTNACNGCNTTYGARAARGCNTCNTCNGARYTNGGNCARYTNAGYAARGAY CCNATHTCNAARTCNCARGARTAYAARCAYYTNATHGARACNTTYYTNTCNACNGARTCN YTNAARAAYTTYACNGCNCARAGYYTNTCNAARGCNAARGARTCNYTNGTNTAYGTNCAR AAYAGYYTNCARACNGCNATHAAYAAYGCNTCNTCNYTNAAYCCNYTNGCNGTNGAYATH GAYAAYGTNCARYTNACNGARAAYGAYYTNGGNATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GGNGCNCARGGNYTNGGNYTNGCNTAYGTNCARMGNTTYYTNGAYYTNGAYGCN AAYGTNTTYTAYGGNGAYATHAAYGTNGARTGYGGNMGNAARCARGARGARGARYTNCAR AGYCARTAYGGNAARGARMGNGTNGTNTTYCAYCCNYTNGAYGTNACNGTNGGNGARCAR TAYGAYGARGCNTTYAARAARGCNGTNTCNCAYTTYGGNAAYATHGAYATHYTNATHAAY AAYGCNGGNATHYTNAAYGARGGNGTNTGGGARAARATGATHGAYATHAAYTAYACNGCN ACNGTNMGNGGNACNAARYTNGCNTTYGAYCAYATGMGNMGNGAYAARGGNGGNAARGGN GGNMGNATHATHAAYATHAGYTCNATHATHGGNYTNGCNGTNCAYCCNTCNCARCCNGTN TAYTGYGGNACNAARCAYGCNGTNMGNGCNTTYACNACNTCNYTNTCNYTNACNAGYGGN YTNAARTCNGARATGGGNATHGARGTNGCNTGYYTNTGYCCNGAYGCNGCNAAYACNGAY YTNATHACNAARYTNGAYGARGAYAARATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATHCAYTTYCARTAYTTYYTNMGNCCNCAYGAR YTNGCNGAYYTNTTYYTNAARTAYCAYGAYGGNTAYGAYAARATHGTNMGNYTNTAYTCN CARGCNGCNYTNAARAAYMGNTTYGTNAGYATGAGYATHGARGARYTNMGNYTNAAYMGN TCNATGGTNGARMGNGAYYTNTTYGCNGCNGTNAARYTNGCNGTNTCNGGNGAYTGYTGY AAYAGY---------GAYGCNTAYACNMGNTTYAGYCCNGAYACNMGNACNCCNGARGTN TGYAAYAAYGCNCAYAGYTGYAGYMGNGGNYTNCAYGTNGAYGTNGGNTAYTTYCARATG GGNGCNGTNACNATH--------------------------------------------- ------------------------------------------------------------ ---------------------------------------------------------TCN YTNYTNYTNGGNYTNCAYGTNATGCAYGGNGTNATGACNGGNATHAGYACNTCNCCNCAY GCNACNCARGCNCAYCARATGGCNGTNGGNMGNCAYACNGARMGNAARGTNGAYTTYMGN MGNYTNGTNCCNAARAARAARCAYYTNAARCCNCAYMGNYTNATGAARAARATGGGNAAR GAYTTYGAYAGYTTYTGGATGTCNGARGARGCNCCNCCNGAYTAYYTNGAYATHATGACN AARMGNAAYGTNGAYGCNTCNYTNCARTCNAARATGACNTCNYTNGAYYTNCCNCAYYTN GCNGCNGAYATGGARATHYTNCARMGNGGNGGNAAYCARAAYGAYACNGGNACNGTNACN ATGGCNACNCCNCCNAARAAYGTNTCNGARGARTCNGCNMGNYTNATHACNGGNATHGTN GARGGNYTNGARTCNTGGYTNGTNMGNATGGGNTCNTGYCCNGTNTAYTAYGARTGGGAR GAYYTNGGNYTNYTNTCNTGGCCNMGNTGGATHMGNAARGGNATGTGYTCNMGN------ YTNGAYGTNGGNAAYCCNATHTTYCARTCNGAYTCNGARTCNACNCCNGCNACNCCNYTN TCNGARTCNTCNTAYTGYTCNTGGCCNCCNGGNATGMGNTGYGTNCCNTCNAARCCNAAR AARATHAARATHYTNCAYTGGACNTGYMGNTAYACNAARTTYACNCARTGGTTYAAYAAR ------------------------------------------------------------ ---------GTNGCNTCNAGYGCNGTNGCNTCNTTYYTNYTNYTNYTNYTNGTNGTN--- GTNATHGTNTTYTCNYTNTCNGCNGAYTCNTGGGTNAARGCNATHATGAARMGNTAYGGN AARGTNAARATGCCNMGNAARTAYTTYGARAARAARAARGARACNAARMGNMGNYTNYTN AAYGARTCNATGMGNTCNTCNTCNGGNAARTCNGTNAAYGGNATHACNCCNTCNCCNATG GTNGAYAARGTNGAYAAYMGNGARAGYATG------ATHCARGGNTGGACNCARGGNACN ---------AARCCNGTNTAYGARGARAARGGNTAYACNYTNGARYTNGGNGARGARAAY GAYGARGARTTYCAYATHGARACNTCNATHGTNGAYAAYGARGTNYTNGAYGTNGGNCCN TAYMGNGGNYTNGGNTCN---ATGACNGGNMGNGCNGTNGARGGNAAYGTNTAYAGYGAY CCNTAYATHTAYACNCAYAAYGAYMGNGTN------------------------ACNCAR AGYATGTCNAARCARYTNGARMGNGAYGAYGTNYTNCARGTNGTNAAYAGYGTNGAYAAY TTYYTNTTYGAYTGYGAYGGNGTNYTNTGGGAYAGYAARGGNCARATHGARGGNAGYMGN GARACNATHYTNAARYTNAARAARYTNGGNAARMGNGTNTTYTAYGTNACNAAYAAYAGY TCNAARAGYMGNCARGARAAYGCNGAYAARTGYCAYMGNYTNGGNTTYCCNGCNGTNYTN GARGAYATHGTNTGYACNTCNTTYATGGCNGCNCARTAYYTNCARATGMGNCARTTYCAR GGNAARGTNTAYYTNGTNGGNMGNAARGARAGYATHGGNCARGARYTNGAYGAYGTNGGN ATHCCNTAYATHGGNACNGGNCCNGAYCCNGTNGAYACN---GARATHAAYGAYTGGYTN AAYATHGARYTNGAYCCNGARGTNAARTGYGTNYTNGTNGGNATGGAYCCNCAYATHAGY TAYATHAARATGYTNAARGCNGCNAGYTAYYTNMGNAAYCCNGAYTGYYTNTTYATHGGN ACNAAYGARGAYTCNTGYYTNCCNACNAARGGNAARATHGCNATHCCNGGNACNGGNTGY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------MGNTGG GARTCNGAYAARGAYAARAARMGNCAYGGNGARGAYTAYGAYCCNGCNGAYCCNACNGAR GAYGAYGAYGARGGNGGNCAYAARAGYGGNGAYGGNTCNAAYYTNTAYTGYCAYGTNTGY AGYGTNTCNGTNTAYGAYGARGARAGYTTYCARMGNCAYYTNAAYGGNYTNAARCAYAAR ACNAARATG--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CCN TCNCCNTCNGTNCARCCNTCNAGYGARCCNGTNCAYYTNAARCCNTAYTTYYTNTCNGTN GTNGARGGNGARCARYTNTCNGGNAGYCAYTCNGAYGAY---ACNCAYATHGCNTCNYTN ATHMGNGAYTAYGARMGNTCNGARGGNAARAAYYTNAAYGAYYTNATHTCNGAYMGNCCN AARTCNGGNGGNGGNGCNTCNAARGARACNTAYGARAARTCNGAYATHAARCAYGGNGAY MGNATHTTYCAYAARTTYYTNAARGARATHCARAARTAYCCNGARCARTGYATHMGNTAY GAYMGNGGNGGNAAYCCNYTNYTNGTNCAYAARYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TTYTTYCARTCNTGYGCNYTNMGNATGGAYAARYTNCCNAGYMGNYTNCARTCNTAYYTN CARYTNCARATHTCNCARYTNTTYTTYAAYGCNGARAAYACNGAYGTNCCNCCNGTNCCN ATHATGCCNYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGACNACNGCNTTYATH TCNCARGAR---CCNGTNTGGMGNGCNTTYATHGGNTAYGCNGGNYTNGTNATHYTNAAR ACNYTNTGYATGAGYYTNATHACNTCNYTNAARMGNGTNGGNAARAARGTNTTYGCNACN GARGARGAYACNGCNTTYTTY---------AARGTNAARMGNGGNGTNGTNYTNAAYAAY ---CCNGAYGTNGARMGNGTNMGNMGNGCNCAYYTNAAYGAYYTNGARAAYATHATHCCN TTYGTNYTNYTNGGNYTNYTNTAYGTNACNACNGGNCCNTCNYTNTCNGTNGCNYTNYTN CAYTTYMGNATHTTYACNGCNGCNMGNGTNYTNCAYTCNGTNGTNTAYYTNACNCARACN CCNCARCCNGCNMGNGCNYTNTGYTTYGTNGCNGGNATGGGNGTNAAYGTNTCNYTNGCN GTNCARATHYTNATGCARGCNGCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GAYMGNATHAGYACNATHAGYACN AARYTNACNGCNGTNGCNAARATGTAYGTNAGYGCNGARMGNTAYTTYCCNGTNGCNYTN ATHYTNMGNCAYYTNGARCARAARTCNTGYGARYTNGAYATHGAYYTNGAYTGGGTNTTY AARYTNATGYTNGARGTNGGNGTNGCNCCNCCNMGNYTNATGGARYTNTAYGAYMGNYTN TAYAARTCNAARGAYGTNATHTGGCARACNYTNAAYMGNCCNMGNCAYGTNYTNGCNGTN YTNCAYGCNTTYATHGAYCAYYTNGCNAARAAYCCNGTNYTNYTNAARACNTCNAGYCCN CCNATGCARGTN---TGGTGYYTNGAYYTNGTNGCNTCNTAYYTNGTNGAYYTNGGNGCN YTNGGNGCNTCNTCNMGNGAYGTNGCNGCNYTNATGGCNGGNTTYAARGCNACNCARGCN MGNYTNGARMGNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNAARGAYTTYCAYATHCCNATHACNGTNAARAARGGNMGNGAYAARGTNMGNGARTGY TTYYTNAARAAYAARCAYGTNACNGAYATHMGNGTNATHGAYATGYTNGTNATHAARGGN CARATGGARYTNGTNGARACNGCNAAYATHTGGAARCARMGNCAYCAYATHATGTCNTAY TTYAARGAYACNGTNAAYCCNAARCCNACNGAYTTYYTNAGYAARTTYTAYGARGGNCAR GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARCARAARGARTCNAARAARAARATHGAYGCNGGNYTN GARATHCCNAARACNAARGAYGARAARAARAARAARAARCARAARGAYAARGTNAARCCN ATGTCNYTNGARGARTTYAAYCARATGCCNGCNCARMGNAARGAYTCNAAYTCNGARGAY TCNGAYGGNGARTCNYTNCCN------------CCNCCNGTNCAYTAYMGNGTNCCNTCN ACNGARCARGAYTCNAARTTYTTYAAYAAYGTNCAYAAYGARGCNGARCARATHYTNMGN CARGAYAARATGCARGARGARTAYMGNAARACNTAYTCNGCNGAYAAYGCNGTNGTNGCN AARYTNAARAAYGAYATHGARYTNMGNGAYAARAARATHGAYCARYTNAARAGYCARATG GARAARATGYTNATHGARATGAARCARGTNAARACNMGNAAYAARCARYTNTGYGGNATH YTNGCNCARGGNGARATGAARGAYAARGCNCARGTNYTNYTNCARGTNGAYCARYTNAAY GARATHAARGAYGARYTNATGGARCARGTNTCNTTYYTNACNTCNGARYTNGARAARGAR AARACNAARAAYMGNGCNYTNAARACNGARTCNGAYAAR---AARACNAAYAARCAYGGN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------MGNTAYGARTGYYTNTAYTGYACNGARCARTTYACNCAYAAYACN YTNCCNGGNATGAARAARCAYTAYGCNYTNGARCAYCCNACNCARYTNYTNGTNATHMGN GAYGTNGTNGCNAARMGNGARAARYTNATGTCNMGNATH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TCNGAYGGNTCN AAYTTYCARGTNTCNGGNATHACNGCNACNYTNAAYAAYACNACNGAYGTNTCNATGGCN ACNCARATHGCNATGGAYTGYYTNAARGGNMGNATHGARAARYTNGGNCAYCARYTNTCN GAYYTNACNTCNGTNTCNATHTAYYTNCARAGYATGTCNAAYTAYGCNGCNGTNAAYGCN ATHTAYAGYAARTAYTTYGARATHAAYCCNCCNACNMGNATHTGYATHCARGTNACNYTN GGNTCNAAYGTNGTNTTYYTNYTNGAYGGNGARGGNMGNGCNGCNACNGAYGGNGARMGN MGNACNATGCAYGTNCARAGYYTNTCNCAYTGGGCNCCNGCNAAYATHGGNCCNTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNTCNTCNTCNGARGCNGAYMGNCARTTYYTNATHGGNCARYTNGCNMGNAARGAYGAR GARYTNGAYGARATHGCNYTNGARAARCARGARATHGCNTAYAARGARATHCARAAYCAY AGYTTYGTNGARGARYTNGAYGARCARGTNYTNGAYYTNTCNGAYGARYTNCARYTNMGN AARATHMGNGARGAYGARCARMGNAARATGTTYGTNMGNGARAARCARAAYATHATHGAR GARATGGARGAYATGATGGAYGCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------MGNAAR MGNGCNCARGGNACNCAYTTYTCNMGNGARCAYYTNGTNCARYTNATGGCNMGNCARACN GAYTGYTGGGAYYTNGAYTCNCARGCNTCNTCNACNGTNMGNGCNYTNAAYYTNGARGCN CCN---------------MGNYTNGARGARAARATGTCNAARGARTGYCCNGGNTCNTCN GTN------YTNTCNGAYGAYGTNGARYTNGARGAYYTNGARGAYGTNGARGARGTNGAR CARCARGTNCCNAGYAARAARGARAGYAAR------------------------MGNATG TCNGGNTCNGCNAAYGARMGNAARATGACNMGNYTNMGNGGNGAYAARMGNGCNGTNGCN CARCARCARMGNAARATGAARGARMGNGCNGARAARGARGARGARAAYGAYGAYGAYGAY AAYGAYATHGCNGAR------GAYGAYGARGGNMGNCARCCNACNCCNAARYTNAARCAR GARAARACNTCNGTNTCNMGNCAYCAYYTNGAYMGNACNACNCCNGCNGTNGGNGGNGCN YTNYTNACNTGYCCNCCNTCNAARAAYAGYAARATGATHGTNACNTCNMGNTCNGGNGAY AGYTAYGTNACNGCNTCNGAYAAYATGGARYTNTCNCCNGCNCARAARAARTAYAAYATG GAYCARYTNAARACNMGNCCNATHYTNGGNCARCCNTCNGGNGAYACNCAYGCNYTNMGN GAYGAYGAYGCNTCNTCNGAYMGNGTNYTNAAYACNMGNTAYGTNCCNACNCCNCCNACN GTNAGYAGYGAYGARGAYAARGARAAYGCNCCNAGYAGYCARAARCARAGYAARGCNTCN AARCCNGGNMGNYTNACNGCNGTNCARGARGGNGTNGGNAARACNTTYATHAARCCNAAR MGNTTYYTNACNYTNGAYGAYATHMGNGCNAAYCAYAAYCARCCNCARGAYGAYGAYGCN GTNTCNATHTCNATGATGTCNGTNGCNTCNAGYGCNTCNYTNGCNTCNCARGTNYTNGAR MGNGCNMGNAARMGNAAR---GARTTYTGGGAYAARGCNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CCNACNTCN AAYCAYACNGAYGCNTTYGGNATGCARGCNTTYAAYCCNGCN---CCNCCNACNCARCAR GARYTNATGGAYATHCAYGAYGGNTTYACNMGNGGNYTNTCNTTYGGNACNGAYGAYTTY AAYYTNGAYGAYYTNGAYCCNYTNAAYCAYAARYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGTCNGGNATHACNTGYYTNGCNTGYAAYGCNAGYTTYGARGAY ATHGARTGYGGNMGNYTNCAYTAYAARTCNAAYTGGCAYMGNTAYAAYYTNAARMGNAAR GTNGCNGGNYTNYTNCCNGTNACNYTNGAYAARTTYGARGARMGNCARAARGCNCARGAR ------GARCAR---AAYGCNYTNCCNACNCARGARAGYTGYTAYTGYGARACNTGYAAY AARTCNTTYAGYAGYTCNAAYGCNTAYGARAAYCAYYTNCARTCNAARAARCAYAARGAY GTNGCNTCNTCNAARGCNAARAARGGNAARAARAARMGNCCNMGNTCNAARACNAAYCCN MGNGCNGCNGTNCAR---------AARGTNGARGARMGNAAYGARGARAAYATGTCNGAR ---GAYGAYGAYTCNGAYGCNGARTCNTGGGAYAGYTAYGARGARAAYGTNATHGGNATG GARGARTGYYTNTTYTGYTCNTTYATHAGYYTNTCNYTNGARGAYAAYYTNACNCAYATG ACNTCNGARCAYGGNTTYTTYYTNCCNGAYGCNGAYTAYATHTCNGAYYTNGARGGNYTN ATHACNTAYYTNGGNGARAARGTNGGNGCNGGNAAYGTNTGYYTNTGGTGYAAYGARAAR GGNAARMGNTTYCAYAAYTGYAARGAYGTNCARAARCAYATGGTNGAYAARGGNCAYTGY AARATHYTNCAYGTNGCNGARACNATHTAYGARTTYGCNGAYTTYTAYGAYTAYTCNAAR AGYTAYCCN------GCNGGNGARAGYGGNACNCARGAYATGGAYGTNGARGCNGTNGAY ATHGCNGARYTNGAYGGNGAYGGNTAYAGYYTNACNYTNCCNTCNGGNGCNGTNGTNGGN CAYMGNTCNYTNYTNMGNTAYTAYMGNCARAAYYTNGTNCCNCARATHGGNGARMGNACN CARAARGTNYTNCCNAARATGYTNGCNCAYTAYAARTCNYTNGGNTGGACNGGNGCNACN GGNACNCARGTNGARCARMGNGCNAARGAYYTNCAYTTYATGMGNMGNGTNAGYAAYMGN CAYTTYATGAARYTNGGNGTNAARGCNAAYAAYYTNMGNCAYMGNTTYMGNAAYCCNAAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CAR AAYCARMGNGGNGGNACNTAYGGNATGCCNCCNTTYCAYATGAAYTAYTCNCARCARGCN TCNATGCCNTCNATGTCNAGYYTNCARTCNAGYTCNTTYMGNAGYMGNTTYAGYGARTTY CCNTCNGAYCARAGYCCNCAYYTNCCNATGCCNATHCCNTCNCCNGCNTCNGGNATGATH GCNGAYMGNYTNCCNAGYTTYAGYACNATHGTNTCNAGYAGYGGNGGNAGY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AGYTTYAGYATHGAR CCNYTNGAYGTNGCNGCNCAYYTNAARYTNYTNGGNGARTCNYTNAGYATHATHGGNATG MGNYTNCARGARCAYAARGGNATGATHGCNGTNCARGGNAGYYTNTCNGTNYTNYTNGAY TCNYTNYTNTGYGCNTGYGGNCCNYTNYTNTGYYTNACNCARCARGTNCCNGGNATGGAY GGNTGYTCNCCNYTNGTNCAYGCNCARACNYTNGAYAGYGTNGCNTAYGTNATGCCNGGN YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARAARCCN GCNAARGAYGTNTCNMGNATGAAYGGNAGYGTNMGNGARATHTCNCCNYTNAGYCCNTCN AAYAARCCNAGYCAYAARGARGGNTCNMGNTAYAGYCCNACNCCNGAYYTNGCNATHGTN ACNCARCCNAARAARYTNGGNGAYAARAARAGYGAYTTYYTNMGNGCNATHMGNAAYGAR AGYTCNATHMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYGGNMGNTAYCCNMGNGARTAYAAYCCNAARGTNCAYGGN CCNTAYATGCCNGGNMGNTTYTAYGGNAARCCNGAYACNCCNYTNGGNGARGTNAARGTN GGNGAYYTNGGNTCNTGGTTYGGNMGNMGNAAYAARAGYCCNCARTCNATGTGGAGYGCN GTNCAYMGNGGNTAYTGGAAYTGGGCNGCNAARAAYYTNCAYGTNMGNCARGGNGGNTTY GCNCCNATHGGNCARGCNGCNATGYTNATGTCNTTYACNTTYTTYGTNYTNYTNTAYAAR GARMGNAGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CARTAYAARGAYTGYGCNCARGARYTNGCNCAYCAYGARGARAARYTNAAY YTNATGGARCAYAGYYTNCARTCNACNCARGAYCARYTNAGYCARMGNGTNACNGARATH GTNMGNCAYGARCARAAYAGYMGNAARYTNCARGCNGARYTNAARGCNGTNAARGARMGN GCNGAYGCNTAYGARGARGARYTNGARGAYCARAARGGNATGATHGAYAARYTNMGNAAR GAYYTNGTNATGGCNAARGARGARTAYCAYGCNTCNGTNCARGARGGNATHGCNTAYAAR CARCARGCNCAYAARAAYCARYTNGARYTNTCNGGNAGYMGNGARCARGARAARATGYTN TCNGAYCARGTNGARCARCARGARCARATHYTNAAYCARYTNCARACNGARYTNMGNGCN GARMGNGARMGNCAYGGNGAYACNGTNCARCARYTNAGYATHAGYAARAARAAYGGNYTN GAYYTNCARGCNGAYYTNGARGCNATGGARAARCARYTNMGNGARYTNCARGAYMGNGTN AARGCNMGNGARGARCAYATGGTNMGNYTNMGNCAYGARATHGAYAAYYTNCAYCARAAR ATHMGNGAYAGYAAYGARYTNATGGCNGARAARGAYGGNCARYTNMGNYTNGCNGAYATG AAYYTNCARACNGCNCARAARCARGCNAARCAYCAYGCNCARGARATHGGNMGNTAYGAR GAYACNYTNTCNCARYTNCARACNGAYCARGARAARYTNCAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AGYCARTTYTTYCCNMGNGARGGNGGNCAYGGN GAYYTNGTNGTNMGNAARMGNACNMGNGGNCARMGNGAYMGNYTNMGNCARYTNMGNCAY GAYAAYMGNMGNGTNACNGTNCARGGNYTNGCNAAYCAYAAYCARACN------TCNTCN GGNYTNTAYGAYGAYAGYYTNTCNGAYTTYAGYGAYGTNTCNMGNACNAARGTNTCNGAR AAYYTNATHTCNGCNTAYAARAAYATG--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GTNTCNCCNAAYTCNGARTTYATHACNYTNGCNGAYAAYATHGARCARYTN GCNAAYAAYATHAGYTTYGARTAYGARGAYGCNYTNGAYACNCCNGGNGAYAAYGAYATG ACNCAYCCNAARGAYGGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNGGNAGYAAYGGNAGYACNGCNAGYGGNAGYAGYAGYGGNAGYTCN ACNCARYTNGAYAAYCARTAYTCNTCNGCNGAYAAYCCNYTNTCNTTY---TCNYTNGAY ATHACNCCNTTYACNAAYTCNTCNTCNTCNACNTCNCCNTCNCAYMGNGGNGARYTNTCN TCNTCNCAYMGNAARYTNGAYMGNAGYYTNAGYGAYAGYGAYAGYGAYMGNTCNGGNAAY GGN------TCNTCNCAYMGNTCNGTNAAYTCNAGYMGNTAYAARACNGARYTNTGYMGN CCNTTYGARGARAGYGGNTCNTGYAARTAYGGNGAYAARTGYCARTTYGCNCAYGGNGCN CAYGARYTNMGNAAYYTNGCNMGNCAYCCNAARTAYAARACNGARYTNTGYMGNACNTTY CAYACNATHGGNTTYTGYCCNTAYGGNCCNMGNTGYCAYTTYATHCAYGARGAYGAY--- ---------------------------------AARGGNGAYGGNTCNTGYAARYTNTCN AAYAGYAGYGGNAGYGGNAGYAGYAGYCCNTCNYTNAGYCCNACNGGN------AAYGAR CAYAAYAAYTTYACNTAYTGYTCNGARTCNACN---CARATGCAYYTNGARAAYACNCAR ATHAAYAAY------TCNYTNACNGTNAAYATH---------------AAYAAYTTYTGY AAYYTNGAYGCNGTNGAR---CARMGNTTYAAYTCNGCNYTNAAYYTNTCNMGNAAYATG TTYAAYAAYAAYAAYGCNACNTCNTGYAAYAARGCNGCNTTY------------------ ---------------GARGARTAYGAYATHTTYAGYAARATHTCNGTNTTYAAYCCNGAY GARGTN---GTNGAYAAYGCNCCNAARCCNTCNAAYTCNTCNGTNTCNTTYTGYAARCAR CCNTCN---------GAYAAYTAYCCNACNTAYGTNGAYACNGTNGTNTGG--------- ---TCNAAYGTNTCNTCNCARAAYGTNGTNCCNGCNGAYCCNTTYCAYTAYTCNCCNACN GGNTCNACNGGNTCNMGNTGYTCNTCNGGNTCNGAR---TCNGGNAGYAGYAGYGAYTGY AGYGGNAGYCARGARAGYYTN---------------------AARMGNACNGCNTGGTGG AAYAAYGARGTNAARCARAARGTNAARGARAARAARATHGCNTGGAARAARTAYYTNGCN AGYMGNAAYACNAARGAYTAYGAYACNTAYAARACNAARMGNMGNGARGCNMGNGAYGAR GTNCAYMGNTCNAARMGNCAYCARTGGGARCARTTYGGNGCNAARYTNGARGARAAYTTY MGNGARAAYCARAARYTNTTYTGGGGNGCNATHAARMGNTGYAARCARGGNAAYCARAGY TCNGTNAARTGYATHAARAAYAARCARGGNGAYATHATHAARGAYAARGARAARATHYTN GAYGTNTGGMGNGARCAYTTYMGNAAYYTNCAYAAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNGGNCCNYTNTTYYTNCCNGTNGAYGARGGNGAYAARATGGTNAARTCN TTYGAYGTNYTNGGNGAYGGNGARGTNTCNGTNCCNACNCAYTTYTTYAARGTNATHGTN ATHGARACNGARGAYGGNCARYTNGARYTNGARTCNTAYATGYTNCCNAAYAAYTCNGGN GAYGGNGGNGGNGARACNAAYYTNGAYGARYTNYTNACNCCNYTNTGYCARATHGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CAYYTNGGNGAYTTY CARGARGTNTTYGGNYTNGTNGARGARATHAAYAARAARATGACNAAYGTNYTNTTYAGY ACNTCNAARGTNTAYCARAAYTCNTCNMGNACNGAYAARTTYGTNACNMGNTTYYTNATG MGNGARATHATGAAYCARGTNACNGCNYTNCARCAYCCNYTNGAYGCNGCNGCNGARGCN YTNGAYTCNCARGCNMGNGARGARMGNATHGAYATHCARCCNATHGARGTNATGGAYGTN GTNAARAAR---TCNAGYAGYAGYGGNATHATHCCNGGNMGNGTNGTNMGNMGNGCNAAR MGNCARGTNAGY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNTGYGAYGGNGARAARAARACNAAYAAYGTN AAYTTYATHGCNGGNACNATHTGYGARGGNATHAAYAAYACNAGYYTNCAYGGNACNAAY GARACNTCNACNAARGAYCARGTNAAYACNGTNAARYTNTTYCARTCNGAYCCNTTYAAY ---------------CCNYTNGGNCCNTTYTTYGCNATHGTNGCNACNTTYYTNGTNGGN GTNGTNGTNTAYTAYACNMGNAARAARTAYYTNCAYMGNCARMGNATHYTNMGNATHTTY MGNCARGCNCARAGYGAYCCNTTY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNCARGAYMGNATHAARGARYTNCAR GARYTNGTNCARCARGARCARAAYGTNATHATGCARACNAGYAAYGCNYTNAAYAARTGY TGYATHGGNAAYGCNTAYTTYGCNGGNTCNGCNGARCARGTNGARTGYAAYMGNYTNYTN YTNATHGCNTGYCARAARMGNCARGTNTAYATGAARGARATHCARMGNYTNAARGARACN TCNATHYTNGAYGCNTCNGGNMGNGGNCCNCARGGNTCNYTNACNATHAGYGAYATHMGN YTNCCNYTNAARMGNGAYTTYGTNAARAARATHGGNACNTCNCAYGAYAAYCARACNCAY TTYTAYATHYTNYTNATHMGNAAYGGNTGYCARGTNATHTGYACNCARATGYTNTCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GTNGARAARTTYGGNCARGAYCARAARGARGTNYTNGAYCAYYTNTTYGCN GTNGAYATGYTNGTNGARAARAARTAYGCNCCNGTNCAYGTNGARGCNGCNYTNCARTCN TGYAARAAYGAYTCNGTNAARGCNGARMGNYTNYTNGARATGCARACNCARYTNGARCAR YTNGGNTTYAGYAGYGARAGYGTNMGNGAYGCNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARGTNGGNGGNCCNYTNMGNYTNGGNAARGGNGGNGGNCCNGGN YTNCARGTNGGNATHGGNGARGTNTCNCCNCCNAARAARYTNAAR------ACNMGNCCN ------TCNGAYATGATHGGNATHGTNGAYYTNGARGAYAAYTCNAARYTNATGAGYCCN YTNCARGGNTTYMGNGTNGTNGTNACNAAYYTNTTYTCNGGNGTNACNCARGARGAYATH ATHGARYTNTTYGGNGTNGTNGGNCCNYTNAARAARGCNMGNYTNYTNAARGCNGGNTCN GTNGARGTNGTNTAYAAYGTNAARGARGAYGCNYTNAARGCNGTNCARAARTAYCAYGGN MGNGARYTNGAYGGNCARCCNATGTAYGTNAARATGACNACNCCNCCNACNGCNACNGTN ---AARGCNCCNCARACNTAYGAYCCNGAYATHACNGGNGARGCNYTNMGNYTNTAYAAR AARCCNAGYAGYYTNGGNGCNYTNCCNGARGGNCCNATHGARGTNCCNACNATHCARMGN GCNYTNTTYAARGTNGGNCCNCCNGCNCCNAAYAARTCNGTNAARTTYACNGTNAARATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GARCAYGARGAYATHGTNGARAAYTTY TGGTTYAARCARTTYACNAARAARACNAAYAARGAYTTYCAYACNTTYYTNTGYATHGAR AAYATHAARGCNTGYTGYCCNAGYAAYACNTAYGGNAARGAYTGYGARCCNTGYCCNGGN GGNACNGARMGNCCNTGYTAYGGNAAYGGNCAYTGYGAYGGNGARGGNACNMGNGGNGGN ACNGGNAARTGYMGNTGYTCNTCNGGNTAYACNGGNGAYYTNTGYACNGAYTGYGTNGAR GGNCAYTAYGARGAYTCNMGNAAYGAYACNCAYACNGTNTGYAARGTNTGYGAYATHTCN TGYAARGGNGGNTGYTCNGGNGCNGGNCCNAARGCNTGYAARGARTGYAARGAYGGNTGG MGNTCNGAYGCNAAYYTNGGNTGYCARGAYATHGAYGARTGYGARGARGARCCNTGYGAR GAYGAYCARTAYTGYACNAAYACNYTNGGNTCNCAYTCNTGYTTYACNTGY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGGNGGNTCN CARAGYAARMGNMGNGTNGTNGTNGARGAYGTNAAYGGNGARGGNGTNGTNCARATHACN GAR---GCNGTNGTNMGNMGNGTNAARGGNYTNCCNGAYCCNCCNAAYGTNGAYAGYCAY CARACNACNGGNGAYAARGTNCARYTNCAR------------------------------ ---------CARGCNATGAAYAARGARATHGARGAYTTYTAYATGGARAARYTNACNGAY YTNCARAARMGNAGYCARGCNYTNCARCARCAYTCNAAYGARCARTTYGCNAARGCNGTN AARGARGTNGARCARAARTTYATGAARTAYACNTGYTCNCCNGTNTGYCARGAYYTNCAR ACNAARGTNYTNGARTGYTAYCARACNAAYCCNCAYTCNATHYTNGARTGYTCNCCNYTN GTNAAYGCNTTYTCNACNTGYGTNGAYMGNGCNMGNATGACNGTNTCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNCCNCARGCNTAYCARGTNGGNYTNTCNGAYTTYAAYGAYMGNYTN TGYCCNGTNGARACNTGYCCNGCNAARACNTGYTTYMGNGAYMGNTCNACNTTYATGGAR CAYTGGTCNATHTTYCAYCARGCNCARACNACNATGMGNTTYTGYCARMGNTGYTCNGCN TAYTTYATGAAYCCNGARGARYTNGARAGYCAYATGATGAARCAYCAYMGNYTNTCNTCN ---MGNGARGCNTAYTGYYTNGTNCARAGYGCNMGNGTNAARGTNATHCCNAAYCCNAGY TAYMGNGAYCCNTCNCCNTTY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGAYMGNGARGAR GARATHAARAAYYTNGCNATHGARATGMGNMGNMGNGARMGNGARMGNMGNCAYAARGAR MGNGARGARGARGARAGYGGNMGNAARGGNMGNMGNAGYGGNMGNCAYAGYTCNAGYAGY GGNAGYAGYAGYMGNAGYAGYAGYAARAGYTCNAARAGYAGYTCNAGYAGYAGYAGYCCN TCNAARAGYMGNAGYCCNTCNCCNMGNAARACNAGYYTNGAYMGNGARTCNMGNGAYMGN MGNCARATGAGYGGNGARGARMGNGAYMGNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GAR------ ------MGNGARATGGAR---------GCNYTNCARCAYAGYAAYACNAARATHYTNAAY CCNGARYTNMGNGGNCARTAYGARGARATHAARMGNTCNTAYGCNGAYATHYTNTAYAAR TGGGGNYTNYTNAAYCARMGNGCNCARGTNYTNAARCAYACNYTNTGYGTNCARGCN--- GGNMGNAARATHGARTTYCCNGTNCCNTGYTCNCARTGYGGNGGNMGNGTNATGAAYGTN CARTGYAAYMGNTGYMGNTAYCCNTCNYTNAAYTGYTCNATHTGYCAYGTNMGNGTNMGN GGNCCNGCNAAYGTNTGYYTNGCNTGYGGNCAYGGNGGNCAYTCNGGNCAYATGAARGAY TGGTTYCAYGGNAAYGCNYTNTGYCCNTCNGGNTGYGGNTGYAGYTGYYTNCARGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARTCNTCNYTNGTNACNTAYGTNAARTCNTTYACNCCNGGNAARATH TAYATHCARAAYGGNTAYGTNATHMGNAAYTAYTTYATHCAYGGNAGYTAYGAYGTNGCN YTNCARCAYTAYAARAAYATGCCNACNGGNGARGTNYTNGCNTAYACNACNCAYCAYACN ATHGGNGTNTCNGARCARGTNCARAGYAARTAYMGNTAYAARGCNTAYATHTGYAARGAY TGYTAYCAYGGNTAYCCNAARATHGAYGTNTAYGARATGAGYAARCCNGAYAGYTAYACN GTNMGNMGNTTYGTNTAYYTNCCNAARGARTAYGAYYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNCCNCAYCARAARMGNMGNMGN ACNTTYCAYGTNGCNGGNCAYGAYTTYAAYATHGAYCARGAYTGGCAYACNGGNGGNGTN GCNGCNGTNGTNTGGGAYGCNGCNGTNGTNYTNGGNCARTTYYTNGCNTCNAAYGTNGAY ATGGTNMGNGGNAARAARGTNYTNGARYTNGGNGCNGGNACNGGNYTNGCNGGNATGGTN GCNGCNGTNYTNGGNGCNGAYGTNACNGCNACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNGTNACNCAYTAYGGNGGN TGYCAYTGYGGNGCNGTNMGNTTYTCNGTNAARGCNAGYGCNGAYYTNGAYATHATHCAR TGYAAYTGYAGYGTNTGYAAYAARAARCARAAYAAYCAYTTYATHGTNCCNAARTCNAAY TTYAARYTNATHAARGGNAARAAYAGYYTNACNACNTAYACNTTYAAYACNCAYGTNGCN AARCAYACNTTYTGYAARGTNTGYGGNGTNCARAGYTTYTAYTCNCCNMGNTCNAAYCCN GAYGGNTAYGGNGTNATGCCNCAYTGYYTNGAYGARGGNACNGTNAAYAGYACNAARYTN GTNACNTTYGAYGGNAGYCARTGGGARAAYGCNTTYAARACNTCNAAYATHACNGARTAY TCNAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGTTYAARAAR TCNAARCCNAARTTYYTNCARAAYGGNAGYMGNGARTCNGTNGAYAGYCARYTNAGYACN TCNAGYGCNAGYAAYGARAAYYTNTCNCCNGCNACNAARGARACNAARGAYACNGTNGAY AARATHYTNCAYYTNMGNGTNCAYTTYCARGTNTAYTAYYTNGGNGTNGTNCCNGAYATH AAYYTNACNAAYTCNAARAARMGNGAYACNGARGCNCARYTNATHGAYGTNGTNGARGAR AGYCARATHGAYAGYAARYTNCARGTNACNGCNACNGAYGARAAYAARGTNGTNATGAAY GTNTCNMGNCAYGGNATHAARGTNYTNGAYATHGCNGGNAARGARGTNYTNCARMGNCAY CCNYTNCAYACNATHGCNCARYTNACNGAYTAYGGNGAYGGNTTYGGNMGNCARAAYATH GCNGTNAARATHGGNCARGTNGGNAARAAYGTNTAYCARTGYTAYGTNTTYCARTGYCAY TCNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GTNCAR GTNACNYTNATGAARGARGGNGGNGGNGAYATHCCNTGGCCNGTNGARACNATHAARCAY ACNAGYACNCARCCNAGYATHCARTAYGCNTGYAAYCCNATGCARTTYGAYTTYAARGAY ATGATGAARGTNGARGGNAGYGGNGAYGCNACNGAYGCNAARAARGAYGARAARGCNACN AARACNGARGAYAARACNGARAARAARGARGCNGTNGTNAARGAYAAR------------ AARAARAARCAY---TCNAARAARAARMGNAARMGNAARAARAGYGCNAARGARGARGGN GGNGARAARGGNACNGGNCARGCNAARGARGARAAR---GAYGGNAARGARGCNGARGAY AARGARGARACNGARGGNAARAARAARAARAAYAARMGNAARAARAARAARAARAARAAR CAYAGYCAYAARAGYAARAARGARGGNGARGARGCNGGNGAYGCNGGNAARGARGCNACN GAYGAYAARGGNGARGAYGGNAARGAYGGNAARMGNTCNCAYMGNAARMGNACNCAYMGN GARMGNGAYGGNGARCARCCNAARGARGGNGCNGARGGNGAYACNGGNGAYAARGAYAAR CARACNYTNGCNAAYGGNAARAARMGN------------ACNTCNTCNCAYAARCAYGGN TCNAARCAYAARMGNAARCAYMGNMGNMGNMGNTCNGAYMGNTCNGARAARGCNAARGCN ATGAGYGCNTCNGARAARGCNAARGTNGARAARGGNATHGAYGCNGTNAAYGCNTTYGAR CCNAARGTNAARATHGAYTAYGAYGARGARGARGARACNCAYATHCCNAGYGAYAAYGAR CARGAY---GTNGCNGARCCNAARATHAARMGNCCNTGYMGNTCNMGNAARMGNCAYMGN MGNAGYAGYAAYCAYAARYTNGCNCCNGARGAYACNTCNATHAARACNGARGAYGAYGGN CARGAYCARYTNAAYATHCCNYTNAARACNCAYAARAARGTNCARGARAAYGCNTCNGCN YTNTCNGARATHGCNAARGCN---------GGNYTNAAYAARCCNACNATHYTNTCNTCN AARGARAARGARACNCARCARAAYAARACNCCNAAYGGNGAYATHYTNAGYACNMGNAAR MGNGGNGCNAGYATHTCNAGYACNGARGGNACNACNCCNGCNAARGCNGCNAARGTNGAR AARGTNGARGCNACNGARGAYACNTGGAGYAARATGGARGGNYTNTAYGARGAYAARGGN GARGARGGNTCNAARAGYAARTGGGAYACNAGYGAYAGYGAYGGNGARGAYGCNYTNCAR AARACNYTNGAYGCNAAY------GCNAAYGARGARAAYMGNGGNAARGARGARYTNGCN ---GCNCARAARCCNGCNAAYGGNAARATHCCNYTNGCNAARTCNYTNYTNYTNACNAAY GGNYTNAAYACNGCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARYTNTTY GTNAAYYTNATGTAYAARGAYATHTTYAGYYTNAAYAARGTNGTNAARMGNTCNGTNTAY GAYAARTTYTGYGGNAARCCNCAYCCNCAYGCNTTYTTYACNMGNATGCARGAYTAYGCN GTNGCNTAYTCNTCNYTNMGNGARGTNYTNAGYATGGAYAGYAGYYTNMGNATHCCNACN ATHCARACNYTNGGNAARTTYMGNTTYCCNGCNATHGTNGCNGGNYTNTCNGAYATGYTN ACNGAYGAYGAYCCNAAYGTNMGNGCNGTNGCNGCNATHGCNYTNGCNCAYGCNGGNAAR AARAARGARTCNACNGTNGAYAARATHATHGGNYTNYTNGARGAYGARGAYMGNYTNGTN MGNGARAGYGCNTGYYTNAGYYTNGGNTAYYTNMGNTCNACNMGNGCNGTNACNCAYGTN GTNGAYMGNTGGMGNAAYGAYCCNATHTCNACNGTNMGNGARGCNGCNGARYTNGCNYTN AGYMGNATGGAYGCNCCNGAYGCNGTNCARTGYATGAARGTNACNAARGTNYTNTCNTCN GARATGAAYGCNYTNAARCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNGCNAAYATHAARCCNGGNGARCAYGARTCNYTN GTNGCNGGNGGNAARAARGCNAARCARTAYTTYTGGCARTAYAAYGTNCARGCNAARGGN CCNAARGGNACNMGNYTNAARYTNGCNGTNGARACNCCNTCNGAYCCNCAYATHYTNAAY GGNTTYGARGAYCCNGTNTTYGAYGARGGNAAYACNATGGTNGCNGGNATHMGNCAYGGN GGNAARGCNMGNAARGGNGAYGGNAAYGARGTNACNCCNAAYCCNCAYAARYTNTTYAAR ATHGGNCAYCARYTNYTNMGNYTNAAYAARAARATHAAYGCNTGYCARYTNGGNTCNGAY GTNCCNATHAAYAARMGNAAYGARTCNMGNAARGARAARAAYAARYTNGCNTCNMGNGCN TGYMGNYTNAARAARAARGCNCARCAYGARGCNAAYAARATHAARYTNCAYGGNYTNGAR AARGARCAYGGNCARATHAAYAAYGTNYTNMGNYTNATHTGGCCNGCNYTNMGNGARAAR ACN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARGAYYTNAARAARATGAARGTNCCNGAYYTNMGNCARGCN YTNAARGAYAARGGNYTNCCNACNAGYGGNACNAARCCNGARYTNATHAARMGNYTNYTN GGNTCNGTNGGNTCNCCNGTNGAY---GGNGGNGAYTCNGCNYTNGAYGAY--------- ------GAYGARATHYTNAARGAYGAYCCNGCNCCNCCN--------------------- ------GCNGCNGCNGGNCCNCCNAARTCNCCNGARAARYTNCCNACNAARGCNAAYAAY GAY---------------ACNAAYGGNGTNCARGARAGYACNGARGARATHCARATG--- ------CCNGCNGAYACNACNGAYAAYYTNGCNAARCCNGTNGARGTNCARAARYTNTCN GAYGCNGARMGNYTNAARYTNMGNGCNGARAARTTYGGNATHACNTCNGARCARGCNAAR AARGAYYTNMGNGCNCARMGNTTYGGNYTNCCNGARAAYAARTCN------GGNAAYATH GAYTCNTCNAAYATHTCNGTNGAYGCNGAYAARYTNAARAARMGNGCNGARMGNTTYGGN ATHCCNGTNACN---------AGYCARACNTCNGARGAYGARMGNAARMGNAARMGNGCN GARMGNTTYGGNACNAGYTCNAAYACNCCNGCN---------AARTCNACNATHAGYYTN AAYTCNAGYGARYTNGARGCNAARAARMGNAARMGNGCNGARMGNTTYGGNYTNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARCARGTNATGGAYAARATHATGGAY CCNGCNAARCCNGARATHCCNGAYATHGARTGYAARTCNGGNGGNYTNAARGAYYTNYTN AARTCNGGNTTYGGNTTYTTYAARAGYTCNGCNAARCCNMGNCCNGGNGAYGCNCCNYTN YTNATGGTNTTYGTNATHGGNGGNGTNACNGGNTCNGARGTNMGNCARGTNAARGARYTN GTNAAYAGYGCNAARCCNGGNTTYGARGTNGTNATHGGNGGNACNMGNYTNGTNACNMGN GARTCNACNYTNCARTCNYTNYTNGTNAARGAYAAYATHAAYGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AAYTCNMGNAARMGNYTN MGNTCNGCNGAYATGAARGCNGAY------GGNAAYCARGGNCCNGGNGGNAAYGAYGAY GARGARACNTAYGAYGAYATHYTNYTNTCNMGNYTNYTNYTNTGYAARGCNGAYGCNYTN GTNYTNTCNGARGGNTTYACNGAYCARGCNGTNAAYTGYYTNCARCARGCNATGGAYATH YTNYTNCAYTCNATHGCNGGNAARGCNAGYCARGAYGTNCARYTNCCNTCNGCNAARMGN YTNMGNGGNAARGCNTCNAGYGTNGARAAR------CCNGAYGAYGARGAYGGNAAYCCN TCNATHGAYTCN------CARCAYGTN---TGGTCNAARCAYYTNATHGGNTGYGCNYTN MGNATGGCNAARGCNTCNTGGAARMGNGARMGNTAYTCNTCNGTNATHAAYAGYTGYMGN YTNYTNGAYCARYTNGAYAGYGAYAAYATGCAYGCNYTNTAY------------------ ------------------------CCNAGYGAYTGYMGNTCNTTYATHGAYTGYTTYMGN GGNMGNGGNTAYMGNACNGCNTGYACNGCNGGNACNGTNTTYAAYCCNCARACNAARAAR TGYGAYTTYAARTAYAAYGTNCCNAARTGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNYTNYTNTGGTCNGARAGYGAYAAR TTYTAYAGYCARTTYCCNGCNAAYGGNYTNTGYACNGCNTAYMGNCCNTTYACNYTNTAY CCNATGAARTTYGTNCAYGAYYTNAGYTTYTGGGARAGYGARTCNGARTCNGARTCNTTY GAYGARYTNMGNYTNCAYGAYTCNATHMGNAAYATHGCNGGNGAYYTNGTNGTNAAYGTN AAYYTNATHGAYGTNTAYCARGARCCNAAYTCNAAYMGNMGNAGYMGNTGYTAYMGNYTN CAYTTYGTNTCNCCNGAYAARTGYYTNCCNTAYGTNACNTCNTGGAARYTNCARAGYMGN ATHMGNATGGARGTNTCNMGNAGYYTNGGNGTNCARYTNMGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYCARYTNYTNYTNGAYATHMGNGAYYTNGARATHAARAGYGTNAARATGCAY GAYAGYAARGARAAYYTNAARTTYAARATHGAYAAYCCNGCNGGNGTNGAYTTYGGNTCN MGNYTNTCNATHGAYYTNCCNAAYYTNACNTCNGCNAGYTTYGARGTNGAYATHGTNTAY AGYACNTCNCCNGAYTCNACNGCNYTNCARTGGATGACNCCNGARCARACNGCNGGNAAR MGNCAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TTYATGMGN GGNYTNGARAARAAYGTNYTNGTNGTNAGYACNGTNGAYCCNTTYGGNMGNAARGTNGTN TGYGARACNGGNAAYAARCCNATGYTNAAYGGNATHYTN---GAYATHAAYGGNTCNTCN CAYCCNCCNGGNAGYACNGGNYTNAGYGTNCCNYTNCCNCCNGTNCCNGGNTGGGTNAAY ACNGGNAAYACNGCNGGNAGYACNTCNCCNAAYACNACNAARGCNATGGCNACNACNATG CCNCCNYTNGGNTCNTCNTCNCCNAARTCNGAYTCNGGNGTNGGNTCNAGYAGYGTNCCN GGNGGNYTNCCN------AGYTCNGTNTTYTCNGAYCARGGNGAY---CCNYTNTCNGTN CAYTCNGARGARGTNGTNGARGARACNGTNGTNACNATGGAYACNGGNGAYGTNAGYTCN GTNGTNACNGAYGGNGGNGARGGNATGGCNGARMGNGARGCNATGGARGGNGAYATGGCN ------GAYGAYMGNGARGCNTCNTCNTTYTCNTCNTCNTCNTCNTCNTCNGARGARYTN TCN---------ACNTCNTTYGARACNGGNCARMGNGTNTCNCARTTYGGNGCNTCNGTN AGYGARGARCCNGAYGARMGNMGNCCNTGGGCNGCNTTYGCNCARGAYCAYGAYAAYAAY ACNYTNGCNGAYGARAAYCARACNTCNAGYACNGTNTCNTCNTCNTCNCCNCCNCAYAAY GCNYTNTCNGARGCNTCNACNTCNTCNTCNTCNGCNACNTCNTCNACNYTNTCNTCNTCN TCNTCNCCNCCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNGAYGAYAARGTNGCNTTYTAYTTYACNATHGTNGTNTAYGARTGYGCNACN GGNTGYGTNAGYATHGCNGGNATHATHACNAAYACNATHAAYGTNATHGTNTTYGTNMGN CARGGNTTYACNGAYAAYGGNAGYGCNAGYYTNYTNGGNYTNTCNGTNGCNGAYYTNATH TGYACNGTNGCNATGYTNTGGGTNTCNATHACNTTYACNTTYGTNTCNGCNAAYMGNGAR YTNCCNTGGGAYCCNTTYTCNTTYATGCAYATGACNGGNGCNTGGCCNCARYTNATHTTY ACNCARATHTCNMGNGGNGTNACNGCNTAYATHGCNYTNGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TCNGCNGGNGTN CCNTCNACNYTNTCNACNCARTTYYTNGCNGCNTCNATHCCNACNGCNATHGTNGCNAGY CARMGNYTNAARTCNGCNGGN---AGYCARCAYMGNCCNTCNTCNTCNCCNYTNTCNAGY CCNATHGCNCCNCCNAARGTNTCNACNCCNCARCARGGNACNAGYATHCCNYTNATHGCN YTNCCNAARGCNTCNACNCCNTCNYTNACNCCNCCNCCNAAYTCNMGNACNCCNACNCCN ACNCARGCNGGNTCNMGNMGNTCNTCNAAYGAYYTNACNCARCARATHACNGGNAGYAGY ---AGYCARCARACNYTNCARCARCARCARYTNACNAAYTTYATHCARGGNYTNACNTCN GGNACNGTNGTNACNGGNAAYCARCARCARCARCARTCNCARCARGTNGCNGGNAGYAAY YTNACNAAYYTNAGYATHGGNAAYYTNGGNCARYTNTCNGGNAAYYTNAAYYTNCARGGN YTNGCNGGNYTNCCNGGNGTNAAYATHGCNAAYYTNAGYGGNYTNCCNCARATGCARGTN TCNYTNGCNCARATHGCNGTNCCNATHACNATGATHAAY---------GGNAAYYTNCAR GCNCARCCNGGNYTNYTNAGYTCNACNGCNACNGGNAGY------TCNACNGCNACNYTN GTNACNATGGTNACNGCNYTNCCNGCNTCNTCNACNAAYACNACNACNACNACNACNATG ACNGGNTCNTCNCARGTNGCNGTNTCNACNGGNTCNAAYATGYTNTCNTTYCCNGTNGGN YTNAGYGGNYTNACNCARYTNATGCCNGTNACNTCNAARGGNCARGCNGGNCARACNATH AARTCNACNGCNATGCCNYTNYTNCARYTNCARGGNCARCARAGYATHCARYTNYTNAGY YTNCCNCARMGNGGNCARGTNAARCARGGNACNAGYAAYTCNAAYACNGCNCCNAGYATH ACNMGNYTNGCNCARGCNGGNACNACNACNGTNCCNYTNTCNACNGTNYTNGCNGGNCAR CARATGACNGCNYTNGGNATGGCNAAYAARCCNGGNCARGCNGGNGGNACNGCNATHACN GCNCARCARYTNATHCARYTNACNAGYGGNCARGGNACNTCNYTNGGNCARGCNGCNTCN CARMGNGCNGCNCAYATHACNTTYGGNAARGGNCARCARGGNYTNCARTTYCAYTCNYTN CARYTNAARCARAGYGGNAGYTCNYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TCNTCNGGNAARGGNAAYGGNCAYAAR GAYGGNAAYCARTCNGAYAARCCNGCNTCNAGYCCNAARTCNAGYMGNGARAAYACNCCN GARAARMGNTCNTCNGARMGNGARAARTCNTCNGAYMGNGARAARACNCCNGARGARGGN AARGTNAARGGNAARTCNAGYGTNTCNTCNTCNCCNTCNGAYCCNACNACNTCNGCNTCN CCNTCN------------ACNTCNGGNGCNTCNYTNACNGARAARAARMGNAARGGNGCN GARGCNGARGARGARTTYYTNAARCARGCNATHAARMGNATHAARAARCARGAYGARGAR MGNATGAARATGCARGTNYTNGTNTCNAAYTTYTCNGARGARCARYTNAAYMGNTAYGAR ATGTTYMGNMGNGCNACNTTYCCNMGNGCNGCNATHAARMGNYTNATGCARAAYATHACN GGNACNACNGTNTCNCARAAYGTNGTNATHGCNATGTCNGGNATHGCNAARGTNTTYGTN GGNGARGTNYTNGARACNGCNYTNGAYACNAGYGARAARTGGGGNGAYTCNGGNCCNYTN CARCCNAARCAYYTNMGNGARGCNGTNMGNGTNYTNAAYAAYAARGGNATGATGCCNACN ACNAARAGYAARAARACNYTNTTY------------------------GTNAARGTNCCN AGYGCNAAYAARYTNGGNCCNGTNCCNGCNATGYTNAGYGGNGAYCCNACNAARATGGAR MGNGGNYTNATHGTNYTNCARGARTGGTGGGGNATGAAYGARCARATHCARGGNTGYGGN AARGAYYTNTCNTGGCARGGNAAR---ATGGTNACNYTNGTNCCNGAYYTNTAYMGNGGN AARGTNACNACNGAYAAYGARGARGCNGGNCAYTAYATGGGNGAYYTNGAYTGGCARGGN GCNGTNGARGAYATHMGNGGNGCNGCNMGNTAYYTNAARGARMGNGGNGTNAARAARGTN GCNGTNACNGGNTTYTGYATGGGNGGNGCNYTNACNATGGCNGCNGCNGCNYTNGTNGAR GARGTNAGYGCNGCNGTNCCNTTYTAYGGNATHCCNTCNGGNGARYTNTGYGAYGTNCCN TCNATHAARATHCCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN GGNTCNGTNGTNGARATGGGNYTNCARATHACNTCNACNGCNAARGARGARACNTGGACN ATHACNAARGARATHMGNAAYAARAAYCCNGTNGTNGGNACNTGGGGNMGNYTNAARGAY GTNAAYTCNTGYCAYGCNYTNGAYTAYGGNTGGAGYAAYTCNCAYTGYTGYCARGARGTN TTY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TGGAGYTCNGTNGCNGAYAGYYTNAAYAARGTNTCNACN GAYGARATHAGYAAYATHTGYCAYYTNATHGCNGARAGYTTYTGYCARGAYAARACNATH AARTCNGAYCARYTNYTNTCNGCNTGGTCNYTNGARGARTGGTGGAARGTNMGNGGNGCN ATGACNGARYTNATGAARAARGCNGTNCARAARGAYTGGAGYAARGAYCARATHAAYCAR GARYTNGGNTCNYTNGAYGAYTCNTAYAARAGYGTNATHTCNGARACNGTNGCNGTNCAY MGNGCNGTNYTNAARCARAARYTNYTNCARAGYACNGCNTCNATHTCNCAYGCNGTNYTN TCNGAYTTYGAYTGGAARYTNCARYTNGCNYTNTCNAGYGAYAARATGTCNAGYYTNCAY CARCCNYTNYTNACNYTNGAYYTNGAYYTNMGNCARGCNAAYGGNGARMGNAARCARGTN GTNYTNGARATGGAYAARGAYGARGTNGCNAARYTNATHGCNTCNYTNGARAGYTGYAGY AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNACNGGNCAYMGNTCNAAR GAYTAYTAYMGN---MGNMGNTCNMGNACNMGNTCNMGNTCNMGN---GGNMGNGARMGN TCNGGNTCNACNTCNMGNCAYGAYGGNTCNMGNTCNGCNTCNAARCARGARAARGAYMGN MGNTCNMGNMGNCARGGNAGYGAYGARACNGAYAARGCNCCNACN------ATGACNTCN TCNGARYTNGCNGARATGMGNATGMGNAARGCNYTNCARGCNGCNGCNGCNGCNGAYGAR AARYTNAARGGNYTNGARGGNCARGGNTCNGGNTCNTCNAAYGGNTCNAAYGGNCAYCAR TCNAGYMGNCCNYTNCAYYTNTCNTCNGCNTCNGCNMGNGAYTTYGCNGAYTCNGTNGCN GCNATHGARGCNGAYAGYTTYGTNCCNGCNTCNTTYAARTCNAAYGCNTCNACNATHAAR GARGAR---TCNYTNGAYCCNYTNATGTCNAGYCAYGAYGAYGCNATHTTYGGNTCNYTN TCNTCNYTNGGNTTYACNATHAARCCNGAYCCNGAYYTNAARCCNGTNCCNYTNGAYCCN GAYTCNATHATGCAYCCNMGNYTNTTYTGYGAYGTNGARGARAARATGAAYMGNTGGGTN GARMGNYTNTCNCAYYTNMGNMGNMGNAARYTNGARGGNGARGCNATG------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GAYAARGAYGARGARAARGARAARGAYACNMGNGAYAARGARMGNAGYYTN ATGMGNGARMGNGARMGNMGNCARGARGARAARMGNCARMGNGARMGNYTNGARAARYTN MGNGARCAR------------------------MGNGAYMGNGAYMGNGARMGNTCNAGY GCNMGNGGNTCNMGNTCNAARTCNMGNTCNGTNTCNCCNGTNATHTCNMGNTCNMGNMGN MGNTCNMGNTCN------------MGNGARMGNACNAGYMGNGAYMGNTCNMGNGARMGN MGNAARGARMGNGARATHGARGARGARGARGARYTNTTYGARMGNMGNAARYTNGARAAR AARYTNMGNGARAARGARGCNGCNTAYCARGARMGNYTNAARAAYTGGGARGGNMGNGAR MGNAARAARACNMGNGARTAYGARAARGARAGYGARMGNGARGARGARMGNAARATHGAR GARACNMGNGARGGNMGNMGNYTNAARGARTTYYTNGARGAYTAYGAYGAYYTNMGNGAY GAYCCNAARTTYTAYAARGGNAGYGCNYTNCARMGNMGNCARAARGARMGNGARAARGAR AARGARYTNGAYAAYMGNGAYMGNCARMGNGARAARGARGARTTYGARGARATHAARMGN AARYTNTTYGAYGARGGNCAYCCNGAYGCNGARACNGARGTNGCNMGNATGGARMGNGAR MGNGARGARCAYYTNCARCCNTGYYTNCAYYTNGARGARGTNAARCARCCNTCNCARCCN CCNCCNGCNMGNCARTCNGARTCNGARGARGARGAYGAYGGNGARGARGARYTNGARGTN GTNTCNAARGARCCNCAYACNGCNAAYAGYACNYTNCAYCARCCN---------CARCCN CCNCCNYTNCCN------------------CARCCNGCNGGNTCNGGNAGYGGNCARMGN GCNTCNCCNTCNYTNTCNACNTCNCCNATHTCNACNGAYTCNMGNATH---AGYGCNCCN NNNYTNTGYATGGAYGAYTCNTCNCARTCNTCNYTN---CCNACNGCNCCNCCN------ ---YTNTCNMGNTTYGARGARACNMGNATGGARATHMGN--------------------- ACNACNTCNYTNNNNCCNGTNATHAGYCCNGAYTCNTCNAGYYTNCCNGGNYTNGCNAGY YTNACNGAYGGNAARMGNAARAARYTNACNGTNGGNGAYGTNTTYAAYCARGAYGAYGAY GAYAGYAAYGARCCNAARAARMGNAARYTNATHCCNYTNGAYTAYGAYGAYGARAARTCN ACNCCNACNGARAARAARGGNGCNACNGCNGARGARAARMGNCARAARATHAARCARYTN ATHGARAAYATHCCNACNGCNAARGAYGARYTNTAYGCNTAYACNGTNGAYTGGGAYATH GTNGAYCARGGNYTNATGGAYAARMGNATHAARCCNTGGGTNACNAARAARATHGTNGAR TAYATHGGNGARGARGARCCNACNYTNACNGARTTYATHTGYCARAARGTNATHGCNMGN AGYACNCCNCAYAGYATHCARAAYGAYGTNGCNATGATHYTNGAYGARGARGCNGARGTN TTYGTNGTNAARATGTGGMGNYTNYTNGTNTAYGARACNGARGCNAARAARATGGGNYTN GTNAARYTNATHYTNGARGGNTAY---YTNCARCARACNCARATHTGGCCNAARTCNGGN CARCAYATHYTNGCNCAYTAYGAYGARGARACNGTNGTNGTNTAYCARGCNTAYAARCCN GARATHGCNGARTAYGCNGTNGARCAYCARMGNTTYGGNGGNCCNCAYTTYAGYTTYGAR MGNATGTCNTGGATHAARACNAAYTTYATGTGGATGATGTAYMGNTGYGGNTGGGCNAAR AARCAYAAYCARGARMGNGTNYTNGCNYTNTGGYTNAGYMGNGAYGGNTTYGARAARATH YTNGCNCARGCNAARACN---------------GCNAARTCNGCNGAYAGYGARTCNGAY GAYGTNMGNYTNCARTGGGAYCCNGAYCAYGAYCCNTCNGGNGGN---AARYTNACNMGN MGNGCNATHCARYTNGGNYTNMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TTYGAYGARGTNCARCARGCNATGTCNGARGCNAARGGNYTNYTNGAY AAYCARGARTGGATHACNGAYGAYTTYYTNGARAARATHGARAARAAYGAYACNYTNYTN AARMGNTTYAGYGAYCCNAARTTYATGGCNGCNYTNCARGARTTYCARACNAAYCCNCAR ACNGCNATGYTNAARTAYAARGGNAAYACNGARATHGARAARTTYYTNATG--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNACNCCNTCNAAYTTYGTNCAYATHAGYCAYGTNGGNTGGGAYCCNGAY AARGGNTTYGAYATGAAYAAYYTNGARCCNGAYATGAARACNYTNTTYCARTCNGTNGGN ATHCARGAYGGNGAYCARYTNGAYAARGAYACNATHGAYTTYATHTAYGAYTTYGTNGAR AARCARGGNGGNATGGARGCNTTYAGYAARGARYTNAAYAARAAYAARTCNCCNCCNGCN CCNCCNGTNCCNGCNATGGGNTCNMGNGGN------GGNCARCCNCCNCCNCCNCCNTCN MGNGCNCCNTCNGCNYTNCCNCCNMGNGGN---GGNGCNCCNCCNCCNCCNCCNCCNCCN TCNMGNGGNCCNCCNCCNCCNACNATGMGNGGNGCNYTNCCNCCNCCNCCNCCNTCNMGN GCNATGCCNGCNCCNCCNMGNGCNCCNCAYGCNGCNCCNCCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TGGGARGCNYTNTAYAARTCNGTNMGNATHGARGGN MGNGTNGARAARYTNAARCARGARYTNTCNGARGCNTAYTTYCAYTCNMGNCCNMGNTCN AGYCARATHGGNGCNTGYGTNAGYCAYCAR---CARAGYTCNGTNGTNGCNTCNMGNGAR ATHYTNGAYAARMGNAAYGARGARYTNCARGCNAARTAYAGYGAYGARAGYATHCCNATH CCNAARCCNGAYTAYTGGGGNGGNTTYMGNGTNATHCCNCAYMGNTTYGARTTYTGGCAR GGNCARACNAAYMGNATHCAYGAYMGNATHGTNTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNAARMGNCCNATGGCNGTNTCNGTNGGNGCNTCNGGNGCNATHATGGGN YTNYTNGGNATGATHGGNGTNYTNTAYCCNAAYGCNCARYTNCARATHGCNTTYGTNTCN GARATHATHCCNCAYTCNTTYCAYGCNGARACNGGNATHAARGCNATHATHYTNTTYGAY YTNYTNGGNYTNTTYATGGGNTGGMGNGTNYTNGAYCAYGCNGGNCAYYTNGGNGGNATG YTNTTYGGNYTNTTYTAYGCNAARTAYGGNAAYAGYYTNATHTGGGGNAAYMGNGAYTCN ATHGTNAARMGNTGGCAYGAYATHMGNGGNAARCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GARTAYGARCCNTTYGAYTCNAGYAAR AARGCNCARATHGAYAAYGTNTTYATHCCNGGNYTNGAYGAYGCNGTNATHCARYTNGCN AARATGMGNAARAAYCARGTNATGAARTGYAARTGYGARGTNMGNAGYACNYTNTCNAAY ACNATGAARTAYTAYAGYMGNATHACNGTNGARAGYGARCCNGTNGGNGARGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNCCNGCNMGNGGNCARCAYTGYGCNYTNGCNATH GGNGAYATHTTYYTNGTNTTYGGNGGNTCNGGNAAYTTYAGYCCNGARATHATGCARTGY CARACNTTYTTYMGNGAYACNTTYTTYATHAARACNGAYTCNTTY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GGN YTNCCNGTNGCNMGNCCNYTNTTYTGGACNTTYCCNGARGAYGARAARACNCARGAYYTN GAYGGNCARTTYATGTGGGGNTCNCARYTNYTNGTNTCNCCNGTNYTNAARGARGGNGAR MGNCAYGTNYTNGCNTAYYTNCCNAARTCNACNTGGTAYGAYTTYCAYACNGGNCARCCN GTNCAYTCNTCNGGNMGNTTYCAYMGNYTNCCNGCNCCNYTNGAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGYTNACNATHACNGAYTTYATHAAYATHYTNAARCARTAYTAYAARAGY TCNGARACNAARATHGARGARYTNGARGAYCAYAARATHGCNACNTGGMGNGARGTNYTN AARCARAARCARMGNCCNTTYGTNTCNATHTCNCCNGAYCAYAGYYTNTTYGAYGCNGTN AARACNYTNGTNGAYAGYCARGTNCAYMGNYTNCCNGTNATHGAYGAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY AGYMGNTCNGCNAARYTNTCNMGNCCNATGTCNGCNATGATGTCNGCNMGNTTYGTNGAR GGNGCNATGYTNGAYGARAARAGY---GARGARTCNAARGARGAYAARGGNGAYGARACN GAYGARGTNAARGCNGCNCARATGAARYTNTTYGGNAARYTNACNMGNGARGARTTYGAR TGGCAYCCNGAYAARYTNGTNTGYMGNMGNTTYAAYGTNCCNAAYCCNTAYCCNGGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MGNCAYTCNCAY GTNGCNAAYGAYGAYTTYMGNTCNCCNCARGTNYTNYTNYTNYTNGGNCARGAYGGNAAY GTNGCNCAYGTNGAYAAYGGNATHGARTAYAAYTTYGAYGTNACNAARTGYATGTTYAGY TCNGGNAAYGTNAGYGARAARYTNMGNGTNGCNGGNTGGGAYTGYTCNAAYGARACNGTN GTNGAYYTNTAYGCNGGNATHGGNTAYTTYACNYTNCCNTAYYTNATGCAYGCNGGNGCN AGYCAYGTNCAYGCNTGYGARTGGAAYCCNGAYGCNGTNGCNGCNYTNMGNMGNAAYYTN GCNMGNAAYGGNGTNGAYCAYMGNTGYACNGTNCAYGARGGNGAYAAYMGNAARYTNCAR YTNGTNGGNGTNGCNGAYMGNGTNAAYYTNGGNYTNATHCCNAGYAGYGARGAYGGNTGG CCNGTNGCNGTNMGNGTNYTNAARGAYACNGGNGGNGTNYTNCAYATHCAYGCNAAYGTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ACNACN CCNATGMGNACNCCNYTNAARGCNMGNAARYTNAAYCCNCCNGTNAARACNCCNAAYACN ACNAGYMGNYTNCCNAAYMGNAGYMGNATHCAYCAYAGYACNYTNYTNCAYTCN---CCN ATGTAYACNCCNAARACNCCNYTNACNAGYTCNAAYACNAARMGNMGNTCNATHMGNYTN ATGAARAARGCNGCNACNGARMGNMGNAGYTCNAAYTCN---AAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARGTNTAYCARMGNYTN TGGCARCAYTTYAARGARGARAAYAAYGGNGGNAARYTNACNCCNAARGARATGAAYGCN ATGGGNYTNMGNGTNACNGGNGCNACNGGNGARAAYAARYTNAARGTNYTNMGNGCNYTN AARYTNTGYCARATHAGYAARACNGGNGAYGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNACNACNTCNMGNYTNGAYCAYGCNTTY TTYGAYGTNCCNTGYGCNACNYTNGCNMGNAAYYTNYTNGGNCARYTNATGGTNMGNTCN ATHGGNACNCARAARATHGTNGGNMGNATHGTNGARACNGARGCNTAYCARGGNCCNGAR GAYAARGCNGCNCAYAGYTAYCARGGNAARAARACNCCNMGNAAYACNGCNATGTTYATG GAYCCNGGNACNAGYTAYGTNTAYAAYATHTAYGGNATGTAYTGYTGYATGAAYATHTCN AGYAARGGNGAYGGNGCNGCNGTNYTNATHMGNGCNYTNGARTCNGTNGARGGNCARGAY YTNATG---------CAYCARGGNMGNGGNAAYAAR------AAYAARAARCCNYTNAAR GARAARGAYYTNGCNAAYGGNCCNTCNAARYTNTGYCARGCNTTYCAYATHTCNAARAAR GAYTTYGAYCARGTNGAYYTNACNTCNTGYACNTCNYTNTGGYTNGARAGYGGNGAYTGY ATHGAYAAYGAYGAYGTNGTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARTTYATHTGYAARTGYTTY TAYTCNMGNAAYATHTTYYTNAARAARTAYAARYTNCAYGTNGCNTAYAAYAAYGARGAR CARTTYCAYGARGAYTTYMGNCARGAYYTNMGNATGAARGGNTGYGCNACNAAYGCNCAR TAYGARGCNGTNYTNAAYGARATHAARGGNGARATHTCNMGNMGNAARGCNTTYCAYMGN GAYTCNTTYCARCCNTAYCARACNATHTCNGARACNTAYCARAARYTNCAYCCNCARATH TGGGAYTTYAARGAYAGYTTYYTNGAYAAYMGNTTYGTNCARATHGTNGAYTCNATHMGN CARGTNAAYAGYAARGAYGAYGCNGARGCNATGATHYTNAARAAYGGNGGNAGYATGATH GGNCCNTAYATHTAYMGNATGCCNATHTTYTCNATHGAYTTYTGYAARYTNYTNGTNGAR GARYTNACNCAYTTYGARAAYAGYTCNTGYCCNAARGGNMGNCCNAAYACNATGTCNGAR TTYGGNATHTCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AGYGCNCARGCNGARYTNCARCARYTNMGNAAY GARMGNGCNMGNYTNATGAAYYTNCARAGYCARYTNAARCAYYTNCARAGYGTNGTNGGN CARGGNAGYGAYGAYCARCARGAYTCNCCNGAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TCN CAYTTYYTNGGNTCNATGACNYTNAARGCNYTNYTNGARGAYCCNAAYYTNAARAAYCCN CCNATHATHGGNTCNTCNGGNGAYCARGCNAARGTNAARAARGARGAY---GGNTCNGAY ATHCCNCARTAYAAYTAYGGNTCNGCNTTYYTNGGNCCNGCNYTNTGGGAYAARTCNCAY GGNATGGAYYTNAAYYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR AARCCNGGNATHYTNATHCCNGGNCARGGNCCNTAYGCNCAYGTNCCNCCNGGNTAYCCN TCNGCNCARGTNATHCCNAAYGGNATGACNACNMGNTTYACNCAYGCNCCNCARGCNTAY GCNGTNGTNTCNGCNCCNGGN---------------AGYCAYCAYCCNACNTAYGCNACN GCNAAYGTNTAYTCNTCNATGCCNTAYCCNCCNACNTCNACNCAYGCNTAYATHCCNGCN GCNCARTTYCCNGCNGGNATGGGNTAYCARACNCCNCAYYTNGCNGGNMGNTCNGCNCCN CCNGCNCARTAYACNYTNCCNYTNCCNGCNCARGCNGGNGCNCCNYTNTTYGCNGCNGGN TAYTCNCCNGTNCCNGCNGGNATHGCNGCNCCNGGNACN---MGNACNYTNCCNATGAGY CCNGTNGCNGCNTAYCCNCCNGGNTAYGCNATHCCNGCNGARGGNACNGCNACNATHGCN TAYCCNCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYGCNGAYTTYAAYGTNGGNTTYGCN YTNGGNTGYYTNCARYTNYTNTCN---CARGGNGTNTTYGTNGCNATGGARGGNAGYATH YTNGAYGGNAAYTAYGTNATGMGNTGYGARGAYGGNAARTTYATGGAYGARMGNTAYGTN YTNAARMGNTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGTCNGARAARCAYGAYTTYGGNGTNGCNCCNGTNACNTGYCAYGCNTTYAGYAARGAY MGNAARGGNYTNGCNYTNTCNYTNAAYGAYTCNAAYGTNAARGTNTAYAARCARTCNGGN GGNAARTGGGARGAYGTNGAYACNYTNAGYGARCAYGCNCARMGNGTNACNAGYATHGAY TGGGCNCCNGARAGYAAYMGNATHGTNACNTGYTCNGCNGAYMGNAAYGCNTTYGTNTGG ATGYTNAARGARGGNAARTGGACNCARATGYTNGTNATHCCNMGNATHAAYMGNGCNGCN ACNTGYGTNAARTGGTCNCCNAARGARAAYAARTTYGCNGTNGGNAGYGGNTCNMGNYTN ATHGCNATHTGYTAYTAYGAYGAYGARAAYAAYTGGTGGGTNAGYMGNCAYATHAARAAR CCNATHMGNTCNACNGTNACNTGYYTNGAYTGGCAYCCNAAYAAYGTNYTNYTNGCNGCN GGNTCNACNGAYTTYAARTGYMGNGTNTTYTCNGCNTAYCARAARGARGTNGAYGARMGN CCNGGNGCNTGYGCNTGGGGNACNAARATGCCNTTYGGNGCNYTNATGGCNGARTTYAGY AAYGGNGGNGGNGGNTGGGTNCAYTCNGTNTCNTTYTCNCCNAGYGGNAAYCARGTNGCN TGGGTNGGNCAYGAYTCNAGYGTNTCNATHGCNGAYGCNACNAARGAYAAYGARYTNATH ATHATHAARGAYTCNTTYYTNCCNTTYATGAGYATHTCNTGGGTNACNGARAAYTCNYTN GTNGCNGCNGGNTAYGAYTGYAAYCCNATGGTNTTYTCNTTYAGYGGNGGNAARATHTCN TGYCARGGNAARYTNGAYGTNCCNCARCARAARGARTCNGGNACNATGAGYGCNATGAAY MGNTTYMGNAAYATGGAYAARAARGCNACNGAYAGYGAYAGYTCNCCNGARATGAARACN YTNCAYCARAAYACNATHACNCARGTNTCNATHCAYAGYGGNGAYAARGCNAAYGCNAGY AARGTNGCNACNAGYGGNGTNGAYGGNAAYYTNATHYTNTGGGAYYTNAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNGCNACNAARTCNAAYCAYTGGGARGTNGAYCCNYTNACNGAYMGNGTNCARTAYATH YTNAAYMGNCCNGGNACNMGNAGYGCNGAYGAYAGYCARGCNAGYTGGAAYGARAARMGN ---YTNTCNAARATGTCNYTNCARGAYGCNTTYYTNMGNAARAARCARAGYTTYATHTCN MGNTGYTCNCARMGNCARAARMGNYTNMGNYTNGCNAARGARGAYMGNCARATGCARGAR TGYYTNMGNYTNGARMGNGARGCNATHTTY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGAARGTNTTY AARTGYGTNATHTCNGGNGAYGARYTNTTYACNGAYAGYGAYAARTTYAARATHGARGGN GGNTTYTAYAARGTNAARGGNAARTTYGTNACN---MGN---GTNGARGGN---GAYGTN CARYTNGAYGGNGCNAAYCCNAGYGCNGARGARGGNGARGAR---GCNTCNGARACNTGY GCNGARTCNGGNGTNGAYATHGTNATGAAYGCNMGNATGYTNGARACNGGNTTYGGNACN AARAARGAYTAYCARYTNTAYATGAARGGNTAYATGAARAAYATHATGACNGCNYTNGAR TCNMGNGGNGCNTCNGCNGAYGARATHGCNTGYAARGCNGARGCNACNAAYGCNTTYAAR GAYGCNATGGCNAARTTYAARGAYYTNCARTTYTTYTCNGGNTCNTCNYTNAAYACNGAY GGNATHATHGCNYTNAAYGARTGGGTNGAYGARGARGARGAYGGNAARGCNGTNTCNACN CCNTAYTTYTAYTTYTAYAARGCNGGNGTNMGNGARGARAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MGNAARCARYTNYTNGGNYTNGTNCCNACNATH CAYMGNATGGARGCNCAYGCNGCNGTNACNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATHGARMGNCARYTNYTNCCNTTYACNATHACNCARGCNAARGAYGCNATHGTN GARATHATHGARTGGCARTTYYTNACNMGNGAYGARGGNGARGARAAYATHGCNGCNGAY GTNGGNTGGACNCARGAYGARGARCCNGARCCNGCNGARACNGAYTGYTGGGCNCARGGN TCNGTNCCNAARAAYATHATHYTNGCNCCNACNCCN------------GTNYTNGAYGAR ATHCCNGARGARGTNGARGGNGCNTCNCARAARGAR---------GARAARGARGTNGAR ACNCARGCNGARCARGARCCNCCNGARYTNGAYGAYATHGTNTCNGARCCNGARGARTCN GCNGARACNYTNGCNAARCAYGARCAR------GARAARAARGARGARGAYAARGCNCCN CARCCNCCNAARCARAARTCNTCNAARACNAARTTYAARCCNTAYMGNGGNAARYTNAAR TCNGCNGGNGTNAGYAARATGACNGARTCNYTNGARGARACNGARATGAARATGATHTAY AAYGARATHGTNGCNTCNATGCCNCCNAGYGARGARAARCCNAGYACNYTNYTNAAYATG CCNGCNTCNTGYACNAGYATHYTNAARGTNCARACNGGNMGNCCNCCNGGNAAYAARGAY GTNGTNTAYGAYGAYYTNGGNAAYGTNATGGCNGTNATGAARYTNGAYCCNGARAGYYTN CCNACNCAYAARGTNAAYGTNAARTAYCAYGTNGTNGAYCCNGCNGTNGARGCNGCNCAR GCNMGNYTNGAYGCNATGMGNAARGGNAARTCNACNGGNAGYMGNMGNGTNAARYTNAAR CCNTCNMGNCAR---ACNATHGARTCNATHTCNACNGGNTCNAARAGYAARYTNCARTCN TAYACNAAYTCNGTNGCNCCNYTNCCNCCNCCNYTN------------------------ ---------------------------------ATHGARGARATGGAYGTNTCNCAYGGN GTNATHATHMGNGARGGNAAYMGNGTNAARAARGGNCCNGGNMGNTAYTAYMGNAARYTN GAYGTNYTNGARGARCAYCARGCNGGNATGAARCCNGTNGCNGTNMGNGTNATGAAYTCN GGNATHACNGTNAAYGAYYTNYTNGAYMGNAAYACNCCNATHYTNMGNGCNYTNGGNGAY TCNTCNCCNYTNCCNCCNATHGTNCCNCARCCNCCNMGNCARMGNCARTCNCARGTNTCN ---------GTNYTNGTNATHGGNGCNGGNGTNGCNGGNGTNTCNAGYGCNYTNAAYATH CARGARTCNTGYGGNGAYGTNACNGTNACNGTNATGGCNGARAARTTYTCNCCNCAYACN ACNTCNGAYGGNGCNGCNGGNATHYTNMGN------------GTNATHTCNATHGGNYTN GAYCCNAARYTNATHTAYGARATGTCNAARGTNACNTAYGARTAYATHMGNGCNYTNGCN MGNTCNCCNYTNGCNTCNATHACNGGNGCNCARCARATHACNGGNTAYGARYTNCAYMGN GAYMGNATGGARCCNGARCCNGAY---TTYAARGAYTAYGCNGAYGGNTAYMGNMGNATG ---ACNTCNGAYGARATHTCNMGNGTNGCNCCNGGNTCNTTYACNGAYGGNTGYTTYTAY ATGACNATGACNYTNGAYGTNACNMGNTAYATHAARTGGYTNACNGAYMGNTTYYTNTCN AAYGGNGGNMGNATGGTNCARMGNAARGTNCAYTCNYTNCARGARYTNTCNAGYGARTGG GAYGTNATHGTNAAYTGYACNGGNYTNGGNGCNGGNGARYTNGTNCARGAYCCNMGNGTN TAYCCNGTNMGNGGNCARYTNYTNMGNGTNMGNGCNCCNTGGATHAARCAYTTYYTNTTY TCNGAYCCNGCNATHCARGTNATGCCNAAYACNGAYAAYGTNGTNGTNGGNGGNACNTAY YTNAARGAYGARTGGGAYACNGARGTNGAYAARAARGCNTCNMGNAAYATHTGGGAYMGN GCNGTNAARYTNATGCCNTCNYTNCARAAYGCNGARATHGTNAARGARTGGGTNGGNYTN MGNCCNTGYMGNGAYMGNYTNMGNYTNGARACNGARGTNYTNCARGTNGAYAAYGGNMGN AARATHMGNATGGTNCAYAAYTAYGGNCAYGGNGGNGGNGGNATHGCNYTNCAYTGGGGN TGYGCNAARMGNGCNGCNGGNATGGTNTCNCARATHYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGGCNATHTTYTTYYTNYTNGCNGCNYTNGCNAAYGCNAAYGAYAAY GAYTGGTAYATHTGGACNCCNATGTAYYTNTGYCCNTCNATHYTNTGYYTNGTNGCNTTY YTNTGGMGNACNGCNGTNGGNAAYAARACNTGGCARYTNYTNATGTCNGTNCARTTYGGN ATHTCNATHYTNATGGGNYTNTAYCARGTNTCNAARGTNTTYGCNATHTCNAGYAARATG AARTCNAAYCCNYTNGTNCAYGARGARGGNMGNGARATGGGNGGNYTNYTNATHATHYTN GCNTGGACNGGNATHTCNMGNTTYTCNCCNTTYGGNAGYCCNAARTCNCAYAGYTCNGGN AAYYTNATGACNGGNYTNYTNGTNGTNGCNYTNACNYTNGCNATHGTNCCNYTNATHACN TGGTCNYTNTGYTTYGTNGGNGAYTGGCAYAARACNYTNGGNCAYTGYTCNGGNATGTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TAYAARAARTAYYTNAGYAARTTYGARCCNGAYCCNTCNGTNATHTGY GTNTCNGGNAARTTYGARAARYTNGAYGARYTNYTNCCNGAYATGAARGARAARGGNGAY MGNATHYTNYTNTTYAGYCARTTYACNATGATGYTNGAYGTNATGGARCAYTAYYTNGAR CARMGNCARCAYAARTTYATHMGNYTNGAYGGNCARACNCCNGTNCCNGAYMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TGYCCNMGNCARTAYMGNMGNTGYYTNCARTCNAARTGGTAYMGNGCNGTNTGY GTNGCNGGNGTNGTNAAYGGNACNGTNGGNGAYTGYGTNCCNGCNACNGGNTAYTGYGCN AAR---------------------GARGAYTGYTCNMGNTCNTTYYTNTGYCCNAAYGAY YTNACNCARGAYTTYATHTAYCCNGAYTGGACNAAYTGYGAYACNTTYTAYCARTGYYTN MGNGGNACNYTNACNCARMGNTCNTGYAARCARGGNGTNTAYCAYTAYTAYAAYCCNMGN ACNTTYAGYTGYGARGARTTYCCNGCNATGACNAAYACNTGYYTNAARMGN--------- ------------------------------------------------------------ ------------------------------------------ATGGCNGAYTCNAARTCN AGYYTNGCNMGNGAYGGNACNATGCARGTNACNGCNAARGARGGNATHGAYTAYYTNAAR GCNGCNCAYAARGAYACNYTNYTNAARGCNCARGGNYTNGTNAARGAYAARNNNNNNNNN NNNMGNGAYGGNACNATGNNNNNNACNGCNAARGARGCNGARMGNYTNYTNGAYGGNAAY AARCCNGAYGCNGAYGCNCARACNMGNGGNCARCARAARCARATHGARGARATGAARAAY GARAARCCNGARCCNMGNGCNAARAARGCNAARYTNGCNAARGAYGGNACNATGGCNGTN ACNGCNAARGARGCNAARGCNYTNYTNGCNGGNGARAARYTNGGNGAYACNMGNCARGAR ACNAARAGYAAR------ACNACNAARACNCCNYTNMGNAARCAYACNACNATGGCNMGN ACNGTNGCNGARGCNAARAGYGTNYTNGAYGGNAAYATHGAYGTNAAYGARGGNMGNAAR ACNMGNTCNCARAGYMGNGGNATHGCNCCNAARCCNGCNATHAARAARGCNGGNACNATG CARCARACNGCNAARGAYGGNAARGCNTTYYTNAAYMGNAAYAAR---GGNAARMGNAGY GCNAARGCNATGGARGARGAYAARCARGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGCCNAAYYTNCCN YTNATH---------------AARTAYACNATGGCNGGNGCNACNGCNGCNGCNMGNACN YTN------GTNAARCARGCNATHAARCCNCAYATHCCNATGATHAARTTYCCNAARMGN GAYCCNAAR------GGNTCNCARACNGGNCARTTYTTYGGNAAYCCNAAYTCNYTNGAR TCNGTNYTNACNCCNAARGTNAGYTCNGGNAARACNGCNAAYTCNACNAGY---TCNAAR GCNAARGGNCCNTCNATHGAYTCNTCNGARYTNCCNCCNMGNTAYAARMGNAARCCNATH TCNAGYGARGARATGGARTTYATHGARAARGGNGGNCARGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AGYCARATHCAYACNCARGCNTCNCCNYTNYTNTTY AARGCNTCNGARMGNYTNTGYGCNGARCCNATGAARMGNMGNAARAARGTNGAYCCNGCN ATHGCNGCNGCNAARACNCARAARAARYTNAARMGNATHGAYAARGARATHAARMGNYTN ACNMGNTTYGGNAARATHYTNAARCCNGTNGARGARATHGARGGNGAYMGNMGNAARYTN ATGGCNAAYGGNGARMGNAARMGNGARCCNGTNGTNYTNACNTTYGARGARTCNGARTCN MGNGCNYTNYTNCAYAARAAYTGGGCNATHTAYMGNACNAARMGNCAYCAYGARATGGTN GCNAAYTTYTCNAARGTNGTNGCNGCNCARCARGARGCNYTNGARGARYTNMGNGCNGAR TCNGARGARYTNTAYYTNGCNGCNATHGARMGNGAYGARTCNYTNYTNCCNYTNAGYTTY GAYGGNCCNAARGARACNCCNCCNATHAARAAYTAYAAYGCNCCNGAYGGNGARTAYGTN GAYACNACNMGNAARTTY---------AGYAGYGAYATGGAYTGGAAYATHGAYATGGAR GTNAAYYTNTTYCAYGCNATGMGNGGNCAYAARCCNGCNGGNGTNAAYMGNCAYTTYCAR ATGATHGCNATHCAYGAYAARYTNAGYTCNTCNGCNAARAARGTNACNTCNAAYGAYGTN TGGCAYCAYYTNTCNACNYTNTAYGAYYTNCARGCNYTNAAYGARTCNGARATHATHCCN TTYCCNAAYAARAAYGGNGAYTTYTCNYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNGCNGARYTNMGNAGYCARYTNGCNAARGARACNGARGAYGCNYTNAARCARCAR GAYGARGARATHGGNYTNYTNATHGGNMGNYTNCARGTNGGNCARGCNMGNMGNAARGCN ATHATGGARAARCARGAYGCNATGYTNAARGAYYTNCARGAYAAYYTNGARMGNCARGTN TCNTCNGCNAGYGGNYTNMGNCCNTCNGTNACNAAYCARATHYTNAAYCAYCAYTAYGCN AARGTNTCNCAYYTNAAYGARCARYTNCAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNTGYATGAGYGTNTGYTTYYTNGCNYTNTTYACNCAYCCNGTNYTNGGN GARGAYGGNCCNYTNAARGTNAGYTTYGARAAYGAYACNACNGTNCARGTNTCNGARGGN GCNGARYTNGTNAARTTYMGNTGYMGNTTYAAYMGNGGNGCNGTNTTYGTNATHAAYAAY AAYGTNYTNATGGTN------------CAYGTNGAYCCNGTNTCNGGNAAY------GAR ACNGTNYTNACNAARTCNGCNAAYATGGTNGARGGNAGYTCNGARTTYTAYTCNATH--- ACN---YTNGAYCARMGNGGNYTNCARGARATGGTNYTNGAYTTYACNATHGTNAARGTN MGNTAYCARGAYGAYGGNCARTTYGTNTGYMGNGTNTCNCCNGGNAAYTCNAAYCCNGAY GGNGARACNGCNCARGCNCARMGNGARGTNYTNGTNCAYMGNCCNATGTCNGAYYTNACN YTNAARTTYGGNGAYTTYGARGCNATHAGYGARTCNCCNACNGAY------------CCN ATHCARATHGAYCAYGGNCARTAYCAYGTNACNTGYACNGCNYTNGGNAGYAAYCCNGGN ACNGARCAYGTNCAYYTNTAYTTYCAYGGNAARGARYTNAGYCAYGARGCN---CCNACN CCNACNYTNATGGARATGCCNCARMGNATGTAYAGYTCNCARGTNGAYGCNACNGTNGAY ATHATGGTNAGYAAYTCNGGNCARGARGTNGARTGYCARGCNAAR------GAYTCNACN GGNACNAGYAARTCNGTNAARYTNAGYGTNAGYGTNAAYATHTAYGAYCCNGARGTNMGN TGYAAYGAYACNGAYGCNTTYCAYGGNCARGCNAAYCCNACNYTNTTYTGYTCNGTNAAY CAYACNGGNYTNGARGTNGAYGGNTAYGCNTAYCARATGGGNGAYACNGGNGARACNTTY MGNCCNGGNGAYAARAAY---------YTNAARAAYATHGTNGTNTCNACNACNGAYGTN TCNCCNGGNATHACNGTNGTNTCNATGGAYYTNCAYMGNGCNGARAARGARTAYYTNGAY AARAAYTTYTAYATHYTNATHGAYYTNAARGGNGGNCAYACNAGYAARGARATGGTNMGN YTNAAYGARGTNGARGCNTCNGTNACN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------MGNCCNATGCARAAYATG--- ---GAYGAYGGNYTNTCNMGNGCNATGGGNACNGGNYTNCARGGNGCNATGATHAAYCCN CARCARCARTCNGCNAAYAAYATGAAYACNGGNAGYATHGCNCCNMGNCCNGCNACNACN ATHGARTCNCARCARCCNAARCCNGCNGTNACNATHCCNCCNGGNYTNTCNAGYYTNYTN ACNTCN---TCNACNAGYGTNCCNACNAAYCCNACNACNAGYTCNAGY------------ AGYACNTCNAAYCCNCCNCCNGCNATGGAYATHAAYTCNYTNYTNAAYAAYYTNATHAAR GTNGGNYTNATHAARGAYTCNAARACNGARAAYGAYTCNAARGCNCCNCCNTCNGTNCCN AARCCNGARGARAARACNCCNCCNGTNGTNAAR---------------------AARGAR GTNAARCCN------AARAARGARGAYATHCCNGAYYTNACNAAYTTYGAYCCNGTNAAR YTNAARATGGCNTAYTCNMGNATHATGGAYGARYTNCAYGARGGNATGCARTGYCAYACN TGYTCNGCNMGNTTYACNGCNGARGAYCARGARAARTAYMGNGCNCAYYTNGAYTGGCAY TTYMGNCARAAYAARYTNGARCARGARATGGTNAARGTNGCNAARAAYMGNAARTGGTTY TAYACNATHCCNGAYTGGATHCARTAYGARGARYTNGARGAYYTNGARGARAARTCNMGN AGYGARATHTTYGARCARATGMGNATGGGNAGYGARGTNTCNTCNGCNGGNACNTCNAAY ATGGAYCCNTTYMGNYTNMGNGCNYTNGARGGNAARGARTTYATHAARAAYCCNGTNGCN TCNGGNGTNGARGGNGARGAYATGTGYGCNACNTGYGGNGAYCCNTTYGAYCARATHTGG AAYGARGARACNGARGARTGGATHYTNAARAAYACNATHAARGTNAAYGGNAARACNTAY CAYCCNATHTGYTAYGARGAYYTNCARGARACNCCNACNCCNGTNACNGAYCCNGTNAAR AAYCCNYTNGAYGCNGARATHTCNTCNCAYGARTCNGTNCCNACNCARGAYGTNCCNGGN ACNGARACNCCNTCNATHGCNCCNATHATHCCNGGNATHAAYACNGARACNGARATHAAR CARGARCCNATHATHACNGAYATHAARACNGARATHATHGARGARCCNATHATHACNAAY ATHAARACNGARATHACNGAYGCNGARAGYGAYATHGCNAAYATHAARGTNGARTCNAGY CARGAYGTNTCNGCNTCNAAYCCNGAYYTNCCNAARTTYGARAARGCNGAYTCNTCNACN GTNAAYCCNACNGCNACNTTYATHTCNGCNYTNAGYAAYCCNTCNGTNACNMGNAAYGTN ATHTCNYTNTGYMGNGARGAYGCNAGYTCNCCNTGGGARATGGAYTCNAAYCCNACNCCN GARYTNTCNMGNACNCCNAGYCCNATHCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GARGARTCNGARTCN GAYTCNGARGARTTYACNGARGARGARATHGCNAAYGAYCCNTCNAARMGNATGYTNTGG GCNGCNGARAAYAAYAARGTNGAYGTNGTNGARGARYTNYTNATGTGYAAYCCNGAYYTN GTNTCNGTNTGYGAYAGYGAYGGNTAYACNCCNYTNCAYMGNTCNTCNTAYAAYAAYAAY CCNYTNGTNGCNAARTTYYTNATHTCNCAYAARGCNAGYGTNCAYGCNMGNACNGTNGAY GGNTGGCARCCNYTNCAYAGYGCNGCNMGNTGGAAYTCNGTNGARACNGCNCARYTNYTN ATHGAYAGYGGNGCNGAYATHAAYTCNCARAGYAAYGGNGGNYTNACNCCNYTNCAYATG GCNGCNTCNGARMGNGARAAYGGNCARATGYTNGARYTNYTNYTNAAYAAYCCNTTYATH AAYACNACNYTNGTNTCNMGNGCNGGNGARACNGCNAARCARATHTGYCAYMGNTCNAGY TGYCAYTAYCAYYTNTTYGARYTNGTNGAYGARAGYGTNAAYAAYYTNAAYAARGCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR AAYYTNYTNAARYTNCARTCNYTNYTNTGYTCNCCNAARYTNACNGTNAAYYTNGCNMGN CAYATHYTNGARYTNYTNTGGGAYAGYGTNCARYTNYTNTGYYTNGCNAARATHGAYATH GAYACNGCNACNGARCARATGGTNGARAARTAYCCNATGATGGTNGCNACNTTYTCNTCN YTNAGYTAYCARGGNGAYGTNACNAARTAYTCNGTNYTNYTNCARTGYATGGARAARGTN YTNAARTGYACNACNACNCARCCNCCNYTNGGNGARCARGTNTAYGTNAARGCNTAYAAR GAYYTNYTNTCNMGNYTNGCNGARYTNTTYCCNCCNAGYCARTTYATHAAYYTNYTNCCN AARGAYGGNAGYYTNTTYTTYYTNYTNCCNTTYATHACNCAYAAYYTNGARYTNGARAAR ATHAAYTCNYTNAARTGYGAYATHATGGGNATGGGNAARGAYYTNYTNTCNCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNCARMGNYTNCCNAARMGNYTNYTNTAYGTNYTNMGN TAYGGNGCNGTNAARGARGGNYTNGARGTNGAYAAYAAYGGNTAYGTNGAYGTNAARCAR YTNCCNACNATHCAYYTNYTNAARGAYTAYACNGARAARGARYTNYTNAAYGARATHCAR ACNTCNGTNTCNYTNMGNAAYAARAAYMGNTAYGARTGGMGNACNMGNGAYGGNGTNACN TAYGTNMGNGCNACNTAYYTNMGNAAYTTYGARCCNAAYCCNTAYCAYGARMGNACNGGN GTNAARACNYTNTTYGARACNTCNYTNTCNTAYATHYTNGAYAAYYTNGAYYTNTAYGAY YTNGARGAYTTYCARGARGARTAYATHATHMGNYTNATGYTNMGNMGNYTNGTNCARMGN AARGCNGTNACNAAYAARAARYTNTCNGCNYTNTTYGTNCCNGCNYTNACNMGNATHAGY YTNGARGGNGTNTAYYTNACNAAYAAYGTNYTNMGNATGYTNTGGACNCARTGYCCNAAY YTNAARCARGCNAGYYTNAARAAYTGYGGNTAYATHATHACNGAYACNGTNYTNGCNAAY TTYGTNAARAARYTNCCNAARYTNGARCAYYTNAAYGTNACNAAYTGYMGNCAYYTNACN GAYAARTCNYTNGCNAGYYTNTCNAARAAYYTNCCNGTNYTNCARATHYTNATHATHGCN MGNGTNCCNYTNATHAGYCCNAARGCNGTNCAYAARTTYYTNCARACNGCNAAYGARYTN ACNGTNYTNGAYGTNTAYTAYATGAARACNACNMGNGCNGARTAYAARGARYTNACNGAY TGYGCNGAYGARMGNGGNGTNGARYTNGTNYTNMGNAARCCNMGNGGNGARGCNGARGAR TCNGARAAYGGNAGYGAYAGYTTYTCNTGYAGYGAYGARGAYGARGAYGAYAAYAGYAAY AAYGGNGARGCNGARGARTCNGARAAYGGNAGYGGNTGGACNGTNATHCARAARMGNCAR GAYGGNAGYGTNGAYTTYTAYMGNGGNTGGGAYGAYTAYMGNMGNGGNTTYGGNAGYYTN GARGGNGARTTYTGGYTNGGNAAYGAYAAYATHCAYTAYYTNACNAAYCARGARACNACN ATGYTNMGNATHGARATGGARGAYTGGAAYGGNTAYTTYTAYTAYGCNGTNTAYGAYTAY TTYMGNGTNGARGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CARCARCARCARCARCARCAYCAYCAYCAYCAY CARCARMGNGAYTAYTCNMGNGGNCARGGNATGMGNCAYGGNGGNGCN---------GGN GGNGCNGGNGGNCAYMGNGTNGAYAAYMGNAAYGAYGGNMGNGGNAAYGARCARMGNGGN GAYMGNAAYGTNACNTCNTCNTTYGTNMGNGGNMGNGGNAGYGGNMGNGGNCARCARATG MGNGARGGN---GGNGGNGCNATGMGNGGNCARGGNCAYCCNMGNCAYMGNGGNMGNGGN GGNMGNTCNTCNGARCCNYTNAARTTYGAYACNGAYTTYGAYTTYGARACNTCNAAYGCN CARTTYGAYAARGAYCAYATHGARAARGARYTNAARAAYYTNACNYTNAGYGAYAARCCN ATHAAYGGNGARAARGCNGARGARGAYCCNGARATHGARGARGARGARGGNGARGARGAR GARGAYGARACNGTNTAYTAYGAYMGNAARAARTCNTTYTTYGAYAAYATHAGYTGYGAR GCNACNGAYAARAGYMGNGGNCARMGNGTNACNTGGMGNGARGARMGNAARYTNAAYAGY GARACNTTYGGNATHTCNGARAAYTAYMGNMGNAAYTAYMGNGGNMGNGGNAAYTGGMGN GGNGGNCARCARMGNGGNGGNTGGMGNGGNMGNGGNMGNGGNGGNGGNGGNGGNMGNGAY GGNGGNTAYATHGCNGGNMGNGARGGNGGNTAYGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CARTAYCCNAARGARGTNGARATHTCN CAYGARGARTTYAARTTYGTNGARCARGTNYTNCCNTCNCCNACNATHCCNGARATHCCN CARCAYTCNTCNTAYCCNACNCCNTCNGGNTGGGTNCCNCCNAAYGAYGARGTNMGNTCN CARCARCCNTAYYTNGTNMGNMGNACNAARAAYCAYGTNYTNCCNGTNTAYCCNAAYCAR AARGARGTNTGGGGNMGNATGATGCAYCAYGTNTCNATHMGNAAYATHGARGGNGAYATH TGGAARYTNGARTCNGARYTNMGNCAYCAYYTNCARGARACNAGYGGNGARGCNGARATH ATHACNCARGTNCAYGARGTNAGYMGNTGYATHMGNATHMGNGGNCARCAYMGNGARAGY GTNGCNAAYTTYYTNYTNGARAARGGNATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ACNGGNGAYAARTCNGCNAGYTCNGAYAGYAGYCCN GGNGCNMGNGCNATHATHGAYTCNATHCARACNGAYTGYTCNAGYGCNGARMGNMGNGAR AARATHYTNTCNGCNATHGAYAARAARGTNCAYCARAARATGATHTCNAGYCCNTTYAAR CCNGCNAARAGYCARCCNAGYCARATHCCNMGNTTYATGGCNTTYYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNATGGAYATHYTNGAYACNGCNGGNCARGARGARTAYTCNTCNGTNAARGARACNTAY GTNMGNGARGTNGAYGGNTTYGTNATHATHTAYAGYATHACNGAYAARGARAGYTTYACN GARGCNGARGCNATHCAYMGNTGGYTNAARMGNYTNMGNGARGTNGAYAAY---MGNGTN ATHYTNGTNGCNAAYAARCARGAYYTNAARGGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TAYGARYTN AARATHATHTTYGTNGTNTGGATGYTNTCNCCNYTNACNCARGGNTCNAGYTTYATHTTY AARAARTTYGTNCAYCCNCARYTNGCNMGNMGNGARAARGAYATHGAYGARATGATHGCN CARGCNAGYCARCARGGNTAYAGYACNYTNYTNTCNYTNGGNTCNAARGGNGTNAAYTAY GCNTCNCARATGGTNATGAARACNGCNATHATGGGNCARTCNAARYTNGTNGAYCAYYTN MGNMGNAGYTAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AGYTCNCARTCNTCNAARAARGTNMGNGAYYTNGCNMGNAARATHMGNATHACNTCNACN CARATHTCNCARAAYGAYATHGAYCCNTCNGTNACNMGNCAYCARCARCARGGNMGNGAY AARCCNCCNAARAARCCNAGYCAYTCNAARGAYTTYYTNGGNMGNMGNGCNACNTTYAGY GARATHATGAAYCARCARAARCCNACNYTNAGYGCNGGNGCNTGGMGNCARCAYYTNGGN CAYAAYGGNGCNGCNCCNATHTCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYTCNGAYGCNAARGCNGARGCNGCNGGNAGYAAY YTNYTNTTYAARGAYTTYCCNMGNAARMGNTCNYTNGTNGAYATGCCNGTNGTNACNACN YTNTAYTAYTGYTGYYTNTAYCAYTTYCAYYTNTCNGARAAYTCNYTNGGNAGYCCNGTN GCNYTNMGNAARMGNCAYCARATHTCNGARAARCARTTYGTNTGGACNGCNATHGGNGCN MGNGCNAARYTNMGNCARTGGAARGAYATHGARGCNATHYTNACNACNAARGGNTGGTTY GGNGGNTCNAARYTNAARGCNGTNATHGGNTTYGAYAARATHGTNGGNATHYTNCAYMGN AAYAAYGCNCCNCCNGAYATHYTNGAYAARTAYYTNGCNYTNATHGARGAYACNAGYGTN MGNYTNCCNYTNGCNAARAARGTNGAYTGYCAYAARGCNGTNATHGAYACNTAYGCNCAR CARAARGAYMGNTCNTCNYTNGARGCNTAYTCNTCNAARYTNGAYMGNTAYTCNAARGAY GGNYTNTAYGCNTAYGAYGTNYTNAAYGGNTCNGTNGTNAARTGGMGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARGARTCN GARGARGAYGGNACNAGYTAYGAYGARGARCCNCCNACNYTNYTNCCNCARATGGAYGCN CAYYTNTCNACNTCNCAYYTNAAYGCNCCNYTNGARGARTCNAARGARACNAAYGAY--- TCNTCNCCNAAYTCNACNCCNAARATGYTNAARTGYGARATHTGYCARAARGTNGCNCCN GCNTCNACNTTYAAYGGNTCNMGNMGNTTYTTYTCNYTNTCNTGYTCNMGNMGNCAYAAY GTNAGYCAYACNMGNCCNGTNGGNYTNTTYAARCCNAARGGNTCNTCNMGNAARMGNAAR CARATGYTNGTNGGNMGNAARGGNTGGMGNACNTCNMGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATHCAYACNTCNAGYATHTCNCAYGTNAAYCAY MGNAARGARMGNGCNATHGTNAARCAYYTNTAYTAYMGNGAYCAYGARAARACNYTNAAR CAYTCNTAYAGYCCNYTNGTNGARYTNCCNGAYTAYTCNTAYATHGAYGGNMGNCCNACN GARATGACNYTNTCNCAYAARGARAARCARGARAARAAYTAYAAYYTNGCNAARCARGTN GTNAARYTNGTNGARGARGTNAARTTYGCNCARAGYCARYTNGCNAARCARGARAARGAY GCNGARAAYTAYCARCAYGARMGNMGNAARMGNCARYTNAARGARAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGTCNYTNGAYYTNGTNTCNAARTGYYTNGARATGGAR------GAYYTNGGNGAYATH TCNAARAAY------AARAARAARAARAARYTNAARTCNAAYGAYGCNATGAARGTNATH AARACNAAYMGNCAYGGNATHTGGAARGARYTNMGNAARGTNMGNAARACNCARYTNAAR GARGTNACNAARAARAARAARAARGARATGTTYAARTCNGCNATHGARYTNTAYAARGAY ---AAYGAYATHGAYTTYACNGAYAARAAYGTNGARACNYTNYTNAARATHTCNAAYYTN GGNAARGTNCARGCNAAYGAYGCNCARAARATHYTNTAYGARCARCCNTGYMGNYTNGCN MGNGAYGTNAAR---CCNGARGAYAARACNGARGARGTNTCNYTNTTYACNGAYGARGAY TTYGARAARTTYGCNCARGARTAYAARCCN------------ATGTCN------GTNCCN CAYGCN------------CCN---CCNYTNGGNGGNGGNAAYCARCARGAYMGNCARAAY MGNAARYTNYTNYTNGARCAYATHCARGARCARAARAARMGNYTNCARCAYGGNCAYCAY TCNTCNTCNAGYAGYAGYCCNACNCCNTCNATHAGYGCNAGYCCNGCNGCNATGYTNAGY AAYCCNTCNTCNTCNGTNCCNGGNATGTCNGCNGCNGARTAYGCNACNATHAGYAAYCAR CARCARMGNYTNGCNYTNCARCAYGCNCAYGCNAAYTCNGTNGGNTTYTTYATHACNCAR GAYTCNTCNTAYGGNAAYYTNATHYTNCCNGTNYTNCCNMGNGCNCCNGAYGTNAARAAR GARACNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ACNCCNAARCAYGTNACNCAYAARGARCCN GCNGTNTCNACNCCNMGNTCNGCNTCNGGNMGNACNGTNTCNCCNGCNCCNGTNGTNGGN ACNMGNTCNTCNTCNGCNTCNCCNMGNGTNACNCCNCCNCCNTCNGCNACNGCNTCNCCN CAYCAYGGNCCNCAYCCNGTNCCNGCNATHAGYGTNTCNTCNAAYTCNGGNGCNGGNGGN AAYGGNCCNACNGAYGAYGGNACNGCNACNAGYACNAARCCNGGNGTNAAYCARGAYATG ACNGARATGGCNTAYAARGCNAARATGGCNGARMGNMGNMGNCARGCNMGNGARAARGCN GARAARGARGCNGARGARGARMGNAARMGNATGGARGARCARMGNYTNGCNGARGARGAR MGNCARMGNCARGARGARGARGARCARYTNMGNYTNGARGARGARACNATHMGNYTNGCN GARGARGCNMGNAARGCNGARGARGARMGNYTNCARMGNGCNATHGARGCNGARGARAAR MGNMGNAARGARGARGCNGARMGNYTNGARCARGARAARAARGCNAARGARGARGCNGAR MGNAARGCNAARGARGARGCNGARMGNYTNGARAARGARAARCARGARMGNGCNAARAAR GARGAYGARGARMGNCARATGMGNAARAARAARYTNGARATGATHATGAARMGNGTNAAR ACNGARCCNGCNCARGARAGYAGYCCN---------------------------AARGTN GARAGYCCNGTNAARTCNTCNGGNAGYTCNCCNAAY------------MGNAGYAAYATG GCNTCNCCNGAYYTNCARGAR---------ATGCCNTCNTCNTTYGCNCARGAR------ ------------------------------------CARGAYAAYTCNGGNTCNGGNTCN GAYGAYAAYAGYGGNAARCCNAAYGARGAYGCNCCNMGNCCNGCNGAYGCNGCNGAYATH AGYGTNGTNGTNGTNGAYGCNGAYAARCCNTCNTCNTCNGARACN--------------- GCNCCNCCNAARCCNGTNGTNMGNAGYGCNTCNTCNGGNGAYATHGTNGAYGGNGCNGGN ------------------GAYGARGAYAARACNGARGARACNGARMGNCCNGCNACNCCN GGNACNCCNGGNAAYACNGCNGCNACNGARACNYTNTCNTCNTCNTCNGCNTCNGCNTCN ACNCCNMGNTTYAARTCNCCNYTNYTNCARCARYTNGTNGARAAYAARGGNGGN---TCN GAYTCNCCNGGNACNCCNAARTTYAARTCNCCNYTNYTNCARAAYYTNYTNGGNAARACN AARGTNGGNGCNMGNATGGGNYTNTCNGCNAGYATGGGNGAYYTNAGYYTNAAYAARGAY AGY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNCARGTNYTNGARTCNCARTCNCCNTGGMGN YTNTCNTTYATHCCNGARYTNGTNTGGGGNATHATHAAYTTYATHGTNYTNTTYTTYCAR ACNYTNTTYAAYCCNAAYAARACNAGYAARGGNGAYAAYTAYACNACNGAYTAYMGNMGN CCNGGN------------CCNMGNMGNMGNATGGGNGGNTTY---MGNGGNGGNGGNGGN GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYMGNATHYTNAARTAYGAYATHAAY ACNGCNGGNGARGGNTCNGAYCAYACNCARCCNCARYTNYTNACNMGNCAYAAYGTNGTN CCNGGNATGTTYYTNATHTAYGCNGAYGGNMGNYTNYTNTTYTGYGAYCAYATHTTYAAY GGNTAYGGNAAYACNAARACNGAYTTYAARAARCARGTNATGAARTCNMGNATGGAYYTN ATGCAYGGNTTYTCNYTNCCNCARGAYTTYMGNTTYAGYCCNTCNMGNGGNGTNCAYGGN CCNMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNCCNACNYTNTAYTCNGGNGAYTGYTAYTCNGAY YTNGTNGAYTCNYTNGGNGAYGGNATGAARYTNTCNTCNCCNGAYAGYATGAAYATHATG AGYAAYATHMGNGTNCCNTAYATHTCNGGNAARCCNCARGAYTAYGGNAAYCARAGYTAY YTNACNGAYATGGAYAAYCARTTYTCNCAYYTNCCNGCNCCNCCNCCNTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARTGGATHYTNTTYMGNTTYCCNGAYGGNGARMGN ACNCCNYTNGARGAYATHYTNCARMGNYTNYTNGARTGYGTNATHTTYATHACNATHGCN ATHGCNGCNYTNGARATGCARTGYMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNGCNTAYGARTAYACN ACNGARAGYCAYTCNGGNCCNCCNCCNATHAARGCNAAYCCNGCNTAYGTNMGNACNMGN CAYGGNATGYTNAARGTNGTNGARATHATHYTNTGYATHYTNATHYTNATHTGYGCNTCN GTNGAYTAYTGGGCNTTYMGNGGNGGNGGNTGGGTNCARTTYGTNGCNGCNTCNGCNTTY YTNACNACNGCNATHYTNTTYYTNTTYCAYTTYTTYAAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNAARTCNAAR MGNAAYGCNGTNAARGAYATHATHGAYAARTGYACNYTNATGYTNMGNGARACNGCNAAY TCNCARACNGAYGARATHAARTCNMGNYTNGAYAGYATHACNGCNCARGCNGAYATGGTN TGYCARYTNAGYGCNGARMGNYTNCARCAYYTNATGGAYCAYCAYTAYGGNATHGCNGTN ACNAAYAARTTYGCNYTNTTYATHGAYGAYGCNGARGAYCCNTAYGARACNATHTCN--- ---------------AARAAYAARAGYAARAARGAYGCNGARAARAARCCNAARGCNAAR CCNAARAARCCNTCNTCNGTNGCNGARGARAARCCNACNGCNCARGAYAAYGCNGGNGCN AAYAARGGN---------GAYAARCCNGTN---TCNAARCARTCNGAYMGNGGNAARGGN AGYGCNMGNAAYMGNGARCCNMGNGARATHMGNGARAAYGAYGGNGAYMGNMGNCCNCCN MGNMGNCARGGN------------------------------------------------ ------CCNMGNGARAAYAARGAYGGNMGNGTNGGNGAYGARAAYGTNCCNCCNGARTTY MGNGARMGNCCN---GAR---GGNTTYAARMGNMGNGAR---------GAYMGNGARGGN GGNTTYGGNGGNGARMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNGGNMGNGGN GGNGARMGNGGNGGNAGYGGNTTY---GGNCCNMGN------------------GGNGAY MGNAARMGNGARTTYGAYMGNCAYAGYGGNACNGAYMGNACNGGNATHAARCCNGTNGAR AARAARGARGGNGGNGGNGCNCAYAAYTGGGGNAGYTTYMGNGAYGAYATHGARGARCAR GGNCARGTNAAYCCNGCNGARGARTCNGGNGAYTGGGGNAAYCARCCNGARNNNACN--- ---------GAYYTNAAYGARAGYGCNGARGCNGARAAYGCNACNGARGARGARGCNCAR CCNCARCARATGACNYTNGAYGARTGGAARGCNYTNAARACNCARCAR---AARCCNAAR CCNGGNTTYAAYACNMGNCARGCNGGNGARGGNGTNGAYAAYGCNCARTGGAARCARGGN GTNGARTAYYTNAARAAR---------------ACNGARGARTCNGARGARGARTAYGAR GARGGNGAYCAYAGYGAYCAYCAYATHMGNAAYAGYAARCARYTNGTNACNGAYATHMGN ATHACNTTYAAYGAYAAYCCNMGNMGNGGNMGNGGNMGN---MGNGGNGGNMGNGGNGGN ATGGARMGNGGNGGNGGNGGNGGN------------GGNMGNGGNACNMGN------GGN GGNTCNMGNGGNTAYAGYGGNAAYAARAARGAYGCNGCNCCNMGNTTY---GAYGARTCN GAYTTYCCNTCNYTNATGAARACNGCNGCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATHCARGTNMGNTAYAARAAYAGYAARCARMGNGTNAARGAYGCNAARGTNCAR GTNGAYAARAAYAARAARTTYYTNGGNAARAARCARAARAARAARGCNGGNYTN---GCN GGNGCNGTNTCNGGNGAYAARAGYACNATHYTNGCNGARMGNCCNGTNGAYAAYGTNTGG ATHMGNAARTTYTAYCCNCCNCCNMGNTTYTCNATHGARGARGCNYTNAAYMGNCAYCAR GCNTTYGCNCARCCNTCNATGYTNGAYAAYGARGARGGNGTNACNTAYYTNGAYATGACN YTNGAYTTYMGNACNAARAARCARACNAARTTYYTNAARAAYATHMGNTCNACNATHYTN YTNCCNCAYCCNTTYCCNTGGGGNACNCCNCCNTCNATHYTNGTNTTYTGYAARGARGAR GARCAYACNAAYYTNGCNGTNTCNYTNGGNGCNMGNAAYGCNGGNACNCCNGCNGARATH ATHAARATGATHGARAAYGGNGTNYTNAAYCCNAARGAYTTYAAYCAYGTNYTNGCNACN GCNGAYTGYGCNGCNGAYATHACNCCNGCNMGNTCNTAYTTYMGNGAYAARTTYCCNCAR MGNGCNAARGGNAAYYTNGGNACNGAYYTNCAYGCNATGTGGCAYYTNTTYTAYTCNGGN TAYACNTAYGARTCNCAYAAYYTNACNGARGCNCARGGNMGNYTNCARGTNCCNYTNGGN CARYTNAARCARCCNACNAGYGARYTNGTNGCNAAYTTYGARACNTAYATHGARTCNATH AGYAARCAYMGNCCNATHGCNYTNGGNCCNTTYATHCARTCNATHAGYGTNGTNGCNCCN CCNTCNCCNGARGARTTYATHYTNMGNGTNGARGARTAYGCNCCNGGNTAYAARAAYGAR GARGTNGAYTCNGAYGAYGARGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TTYGARACNTGGCARGGNGTNYTN ATHTTYYTNYTNATHGCNYTNGCNGTNYTNATHGTNGTNGTNTTYGTNMGNMGNMGNAAR AGYAARAARYTNYTNTAYGTNAAYCARGGNYTNCCNCCNCCNACNACNGTNATHGTNTAY GAYCARGAYCAYYTNGCNTTYGARAAYAAYATGTAYACNGARGCNAAYMGNAAYAAYACN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CAYGAYATGTCNATHGCNAAYGTNCAYATHATHGCNTCNGTNCCNGGNMGNCAYGTN ATGAAYAGYAARCAYCARTGGGGNCAYYTNAARYTNAARAARGTNYTNTCNGARMGNGGN CCNGAYCARGGNYTNGTNMGNAAYTGGCCNYTNGTNGGNCARTTYTCNAGYATHGGNTCN YTNGGNGCNGAYCCNAAYGCNTGGYTNYTNAGYGARTGGGGNCARTCNYTNTCNTCNTGY AARAARTCNATGCCNAGYTCNATHTCNGCNTCNAARYTNCARYTNATHTTYCCNTCNYTN GAYAAYATHMGNYTNAGYYTNGARGGNTAYAAYGGNGGNGGNTGYGTNCCNTAYAGYATH AARACNGCNTCNAARCARCCNTGGYTNACNCCNTTYYTNAGYCARTGGAARTCNGAYGGN MGNGGNMGNTCNCARGCNGTNCCNCAYATHAARAGYTAYACNMGNTGYTCNCCNGAYGGN TCNCARTGYGCNTGGTTYGCNGTNACNAGYGCNAAYYTNTCNAARGCNGCNTGGGGNTGY YTNGARAARAARGGNAGYCARYTNATGATHMGNTCNTAYGARATGGGNGTNYTNTTYYTN CCNCCNGAYTTYGGNTGYAARAAYTCNTTYCCNGTNAGYAGYAAYGCNGAYTCNGTNACN GGNGGNGAYMGNMGNGTNTTYCCNYTNCCNTAYGAYYTNCCNCCNACNACNTAYAARAAR GGN---AARAARTCNGTNGARYTNTTYTAYGAYGTNGTNTCNCCNTAYACNTGGTTYGCN TTYGARGTNATGTGYMGNTAYCARTCNMGNTGGAAYATHAAYYTNAARYTNAARCCNTTY TTYYTNGGNGGNGTNATGCARGCNTCNGGNAAYMGNGCNCCNGCNACNGTNCCNAAYAAR GGNCARCAYAGYATGGTNGAYGTNATGMGNTGYMGNMGNTAYTTYGAYGTNCCNYTNAAY ATHCCNMGNGAYCCNGGNGARYTNATGTTYGTNAARGGNACNYTNAARGCNCARMGNTTY YTNACNGCNYTNGAYATGCARTAYCCNGAYAARGTNGARGCNGTNTCNMGNGARTTYTGG ATGMGNGGNTGGAGYMGNGAYGARGAYYTNTCNGARGAYGCNAGYATHGCNGARGCNGCN ACNAARGCNGGNYTNAGYCARCARGAYGTNCARCAYYTNYTNGCNMGNACNAARGAYCCN GARGTNAARAAYAARYTNAARAARGTNACNGAYGARGCNYTNGARYTNGGNGCNTTYGGN TCNCCNATGATHGTNTTYGAYGTNAAYGGNCARAARGARTGGATHTTYGGNAGYGAYMGN TTYCCNATHYTNGCNCARYTNYTNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ACNGTNYTNGCNGTNGTNAAYATHGTNATHGARAGY AARGGNGAYMGNYTNMGNYTNTTYCCNTAYATHATHGCNGGNTTYGTNTTYACNGGNGCN ATGYTNACNYTNAGYGGNGAYYTNGTNATGTCNGCNAARTAYAARACNGTNGARAGYYTN CAYACNCCNCARTCNYTNCCNGCNACNGTNAARACNATHATHGGNAAYGARTTYATHYTN AGYTGGGGNTTYGCNYTNGAYATHGTNACNGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AAYTAYGCNYTNAARGCNTTYMGNTGYCAYCCNYTNACNMGNYTNGCNTTYGTN CCNGTNTTYYTNTGGYTNYTNATHGARAAYCAYACNGGNATHGAYYTNCCNTGGGCNCCN CAYMGNYTNYTNCCNTGGCARATHATGGGNGGNCCNGCNAARCAYCAYGTNCAYCAYACN CARGGNCAYGGNCAYTAYCARCCNTTYTTYACNTAYYTNGAYAAYTGGYTNGARCCNGGN ------------------------------------------------------------ ---------------------------------------ACNYTNCARCAYCCNATGGTN ---YTNACNAARAARMGNCCNMGNGAY--------------------------------- ------------------------------------------CCNACNGAYGAYYTNTTY YTNAGYTCNATGCCNGGNATHGTNCCNGCNTAYAARMGNATHGCNGTNGGNGAYTCNGTN GGNAARGGNGGNATHCCNYTNTAYCCNAGYAAY---YTNATGTCNCCNTAYCARCARCAR GCNGCNTCNYTNGTNCCNYTNCARCARCAYCCNTCNTAYATHCCNATGTCNYTN------ ------------------GCNGGNCAYCCNCCNACNGTNCCNMGNTTY------------ ------------------------------------------------------------ ------------------------------------------------------MGNMGN GGNAGYGGNMGNMGNGGNYTNMGNMGNCCN------TCNGCNGGNMGNAAYMGNATHCAR AAYGARACNATHAAYTAYCCNACNAGYTCNTCNACNTCNTCNAAY------------GCN GTNAAYYTNGAYAAYAGYGAYGAYGARYTNCCNGAYATHCCNTTYGARGTNTCNAGYACN AGYGCNGARGCNAAYAAYTTYATGACNTCNCCNCCNTCNGTNAARATHACNTGYCCNATH TGYYTNGAYGAYTTYAARCARATHAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TTYCCNGTNTCNAGYGGNTCN CAYCAYMGNGCNAAYGARTCNGARTGGGTNCCNGTNMGNACNACNGCNACNCCNTCNTCN AGYYTN---------ACNTCNAAYAARCCNYTNGCNGCNATHATGGCNCCNACNGAYTCN MGNCCNGARCCNTCNCARAGYATHTTYCCNTCNGTNACNAARAAYATGGAYATHGGNGCN ATHATHTCNGARMGNYTNCARGCNGTNMGNAARYTNCARGCNAAYCCNTAYGAYGTNCAR GCNYTNTCNTCNATGCAYAARGCNCARGARAARGCNAGYCARTGGGCNCARTCNAARCAY YTNCCNGGNCARTTYGTNGGNTCNACNGGNGCNCARGTNATGTCNCARGARCARYTNATG GGNGAYAARMGNAAYCARGCNTGGGTNMGNAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNAARCARTTYCCNGTNGTNGCNGAYACNCCNGAYYTNATGAARGGN TTYMGNACNGCNTGGTTYGARAARGTNAARGAYGTNMGNMGNGCNGARAARMGNGAYGAR GARTTYATGAARGARYTNTTYMGNCARGTNTTYATGGARGCNGTNTAYCCNATHCARCAY YTNGCNACNYTNCCNCCNTAYMGNATGGGNGAYGAYGARAAYGAYAARATHMGNCARGAR CAYATHYTNMGNTAYAAYGARATHAARMGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MGNAARCARAARGCNMGNGARCARACNGARGCNMGNGARGCNAAYGARAAYMGN ATGMGNYTNGARMGNGARGARMGNGARAARGARMGNCARMGNGARMGNGAYGARMGNMGN CARAARGARMGNGAYGTNGAYMGNMGNMGNGAYMGNGAYMGNGAYMGNMGNMGNMGNAGY MGNTCNMGNAGYMGN------------GAYMGNTCNMGNAGYMGNGAYMGNGARMGNMGN MGNCARMGNAGYTCNAGYMGNGARMGNAARGAYMGNMGNAGYCARAGYMGNAAYMGNGAY AARMGNMGNGGNTCN---------------------MGNTCNCARMGNTCNAAYAGYMGN GARMGNMGNMGNGAYAAYMGNMGNTCNTCNGAYMGNAGYTCNMGNGGNMGNGCNMGNTCN GGNTCNMGNGAYAARAARAGYMGNAGYAAR---GAYCARGARTGYGARMGNAAYGAYTCN MGNMGNGARAGYGGNMGNGAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CARAARGAYAARTCNGARAARGARAARMGNGARAARGAR---YTNGCN GCNAARCARGAYGCNGARATGGTN------AGYGAYGARGARGARCCNGGNCARCARATG GAYGCNGGNGAYTTYGCNMGNGAYYTNGGNATHGCNTGYGTNGTNTGYMGNCARTTYGAY GTNAGYTCNGGNAAYCARYTNGTNGARTGYCARGARTGYCAYAGYYTNTAYCAYCARGAR TGYCAYAARCCNCCNGTNACNGGNCARGAYGTNMGNGAYCCNMGNTTYGTNTGGTAYTGY TCNMGNTGYACNAARAGYTTYAARAARATGATGGCNCARAARCCNGCNAAR---CCNGCN AARGCNACNGCNCCNYTNTCNCAYATHGCNAARGARTCNACNTCNACNATHGCNAARATH AGYAARCCNGARGCNGAYGCNGGNAGYCARGCNTTYMGNMGNATGGAYCARAARGCNATH GTNCCNACNAARGAYACNAGYAGYCAYCCNTCNCCNTCNAARGGNATGGTNGGNYTNGCN GGNYTNGCNGCNAAYYTNACNAARCCNMGNGGNGARTCNAARAGYGCNTCNGTNTCNAAR AARCAYGARCAYMGNGGNGGNGGNAGYGAYAGYTCNAARATGCCNTCNGGNAARTCNGAR GTNAARGCNTCNGGNAGYAARCARGAYGCNAGYGGNAGYGGNAARGCNTCNGCNTCNTCN TCNTCNAARACNGAYGCNCCNMGNAARGCNGAYGGNGGN---AARCCNTCNGGNAARGAR GAYCAYCAYAARGARGGNAARATHGAYAARAARTCNTCNGAYAGYGCNGCNAARAARGAR GARMGNAAR---GARAARGGNGARTCNAGYGCNGGNMGNTCNTCNACNGCNGCNAARGAR GARAARAARTCNGARACNGTNGTNMGNTCNTCN---------CCNTCNCAYTCNGGNTCN CCNGGNAAYTCNAGYTCNCCNCCNACNTCNCCNGCNACN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CCNGCNTCNYTN GTNCARAGYAARCARGCNTTYGCNGARATHGCNAGYCAYCARACNGAYGTNGTNGTNAAY AARTTYGARGAYCAYYTNTTYATHATHACNACNCARTAYCARAARYTNGGNACNGTNGTN GARGTNTCNMGNGAYGTNGTNACNGAYGARGTNCARGGNYTNYTNCCNATHTTYTCNACN AARGTNYTNYTNGGNAARGAYGARCCNATGACNCAYGTNATGGCNAAYACNATHGTNAGY GCNYTNAAYCCNCCNATHCCNGTNATHYTNACNYTNGCNYTNAARGTNACNACNCCNGAR GCNGTNCARTCNGTNATHGARYTNATHAARTCNTGYYTNATGGCNAAYAAYTTYCAYGAY GARGCNMGNMGNMGNCARGAYGTNYTNGAYMGNGCNTGYAARTTYMGNAARGARATGGCN YTNGCNGCN---CARTCNGGNCARGCNGCNMGNTCNGTNGARCAYGGNATHAARCCNGAR AARATHATGTGYACNGAYCARGGNCARTTYTAYCARACNMGNCCNAGYGTNCAYGTNTGG ACNGGNCCNGARMGNAAYMGNMGNGCNTAYGAYCARAGYMGNGARGGNCCNGTNYTNGGN AGYTCNTGGMGNCARYTNGARMGNGARATGAAYTTYMGNCARAAYTGYYTNAGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGCCNAAR TAYTGYGARGAYGTNGAYGARCARCCNGCNAARCCNMGNYTNGCNTGYCARGGNATHMGN GAYGAYYTNYTNGARTGYYTNCARAAYAGYGAYTGYTGYAARMGNGAYAARTTYACNCCN MGNGARTGYATGAAYAARGTNGGN---------GAYCCNTCNGTNCCNTAYCARTGYCAR AARYTNMGNYTNGCNTTYATHGARTGYMGNMGNTCNATGYTNGAYATGMGNACNMGNTTY MGNGGNMGNAARGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GAYAARTCNMGNAARAAYGCNATHCARGCNAARATHAAYMGNGARAARAARAARGCN TAYATHAARAGYYTNGARGAYGAYATHTCNACNYTNMGNAGYGAYAAYACNAAYYTNAAR TCNGARAAYGCNMGNATGCARGCNTCNATGTCNGAYYTNGARGARGARGTNCARTAYYTN AARTCNGTNYTNGTNAAYTCNAGYTCNYTNTCNCAYYTNYTNAARAAYATHTCNGGNGTN AARGARGTNAARYTNTCNGCNACNATHGTNGGNMGNAARMGNTCNGTNGGN------GAY GAYCAYTGYTAYAAYATHGTNGARAGYGTNCCNGARAARMGNGCNMGNMGNATHGARGAR AAYYTNAARAARGCNGGNGTNTGYYTNCAYGTNGAYGGNGGNTCNGCNTGYYTNGARTTY TGYGCNCAYTGYTCNAARYTNGCNAARAARTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GTNGTNAARGCNATHGTNAGYGCNGCNTCNGGNGTNYTNTTY GGNATHGCNATHGARAARGGNMGNGTNTTYGAYCCNCARGTNATHMGNGAYCARATGYTN TTYMGNMGNTTYGCNYTNYTNAARATGTTYYTNTCNGCNTCNGCNGGNGCNATGYTNAGY TTYTGYYTNATGAGYACNGCNCCNCARACNATGMGNMGNATGMGNAGYGCNTTYCARYTN TTYAARCARTCNYTNAARTAYCAYACNGTNGCNGCNGTNGCNATHGGNGGNGCNYTNYTN GGNAGYGGNATGACNATHTGYGGNGCNTGYCCNGGNACNGTNGCNGTNCARYTNGGNGCN GGNGTNCCNAAYGCNTGGGTNACNATHGCNGGNGGNYTNTGYGGNGCNACNTTYTAYGCN GTNACNGAYGTNTAYYTNAGY---CCNYTNTTYGARAAYTCNCCNAAYGTNAAYTTYAGY YTNAAYAARGTNYTNGGNYTNGAYTAYATHACNYTNGCNYTNCCNYTNGCNTGYTGYATG GCNATHTCNGTNTTYGGNATHGARCARTTYTCNCCNTGGTTYGARGARATHCCNAGYAGY YTNYTNACNGARGGNGTNATGAARGCNGGNGCNTGGCCNCCNTTYGTNACNGGNATHATH GTNGGNACNYTNCARATHCCNATHGTNYTNGCNAAYCARGAYACNATHGGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GCNGGNCCNATGCCNAAYTTYGCNTCNAGYTAYGGNTTYGGNGGNGCNGGN TCNATHGAYTCNCAYCCNACNATHGAYYTNTCNGAYTTYCCNACNYTNAGYAGYMGNTCN TCNGCNACNCCNAAYCCNYTNCCNTCNACNMGNAAYTAYGTNGGNATGGTNAGYAARCCN GCNCARGAYTCNGCNCCNGARTTYAAYATHTCNCARGARGARTTYCCNGCNYTNCCNGGN TCNCARAAYCCNCCNGTNCARTCNGGNATGTCNGAYTAYMGNGGNMGNGGN---MGNAGY AGYMGNGGNMGNGGNGGNCCNCCNMGN---GGNTCNTTYMGN---GGNMGNGGNGGNTAY ---ATGGAYMGNGARGGNAGYMGNGGNGGNTTY---MGNGGNMGNGGNGGNTTYTCNMGN GGNMGNGGNGGNCCNCCN---AGYMGNGARGGNATHTCNCCNCCNMGN------ATGTCN MGNAGYTAYGAYTCNACNGAYMGNGGNMGNGGNCCNCCNCCNAGYMGNMGNACNGAYMGN TAYGARGAYTCNTAYGAY---AGYMGNCCNCCNYTNMGNATGAARGAYYTNTAYCCNTCN CCNCCNMGNGAYTCNGGNMGNAGYTTYGAYMGNCAYTCNCCNCCN------CCNMGNMGN GAYMGNGAYTAYCCNTCN---MGNCAYTCNGAYTTYAGYTCNTCNMGNGGNGAYTAYYTN AAYCCNMGNAGYTAYAGYCCNCCNMGNGAYTCNGGNTAYGGNTCNTCNTAYAARGAYTCN TAYAGYTCNAGYYTNMGNGARGARMGNMGNCCNATGMGNGAYTAYCCNCCNGTNMGN--- ------------GGNAGYGAYTAY---GAYMGNMGNGAYTTYMGNGAYACNCCNMGN--- GAYTAYGGN------TCNMGNGAYTAYCCNTCN---------MGNAAYGGNGAYTTYMGN GAYTCNATGAGYAGYMGNGAYTTYMGNGAYGCNCCNMGNAGYGAYMGNTAYAGYGGN--- ---------------------------AGYMGNGGNGGNMGN------------------ ------------------------------TCNMGNTTYGAYGAYMGNGGNCCNGGNMGN GGNAGYMGNGAYGAYMGNGGNMGNGGNTTYGTNAAYGGNTCNMGNGGNCCNMGN---GGN GCNCCNMGNGGNMGNGGNMGNGAYTTYTCNGGNAGYMGNGCN------GAYMGNMGNTCN CCN---------------------GTNMGNGARGGNCCN--------------------- ---------GGNGGNAARMGNCCNMGNYTNGAYTCNGGNGAYTAYMGNMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR AARYTNCAYAGYTGGYTNATGYTNGAYYTNCCNYTNMGNTGYGTNAARGTNGCNYTNYTN GARGTNACNGGNCAYACNMGNAAYGGNGCNGAYATHGCNGCNCCNYTNYTNMGNMGNGTN YTNACNGARGAYTTYGARMGNAGYTCNAAYGCNGAYTAYYTNYTNCAYTTYYTNYTNGTN AARAARTGGAARGGNYTNGARACN---YTNTCNGAYATHGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TTYCARGCNTGYGAYGTNGARGGNAGYGGNAARATHACNGGNYTNAARGCNTCN GARYTNTTYCAYGCNTCNGGNYTNAAYGCNGAYGTNYTNMGNCARATHACNGARYTNTGY GGNGCNAARMGNYTNGGNCAYTTYGGNMGNAGYCARTTYTAYATHGCNYTNAARYTNGTN GCNATHGCNCARACNGGNYTNCCNGTNAARYTNGAYTCNYTNAAYACNGTNAARGARATH CCNYTNCCNAARTTYGARCARGCNGCNAGYGAYMGNAARAARCARCARAGYCAYAARCAR GARAAYGGNAGYTGGGCNATGTTYGARGAYGARGARAGYCAYATGYTNATHGGNGGNGGN GTNAARCARCAYTAYACNGGNYTNGARCCNCCNAAYTTYGAYTCNTCNTCNATHTCNTCN GARGCNGARAGYGTNGAYGAYGTNTGGAGYATHAGYGAYGARCARMGNGARTAYTAYATH ATGCARCCNGAYYTNAAYAAYGTNATHACNGGNCCNGTNGCNAARCAYTTYTTYGARAAR TCNAARYTNCCNGTNATHGARYTNTCNAARATHTGGCARYTNTCNGAYYTNAAYTGYGAY GGNGCNYTNTCNATGGARGARTTYTGYATHGCNATGCAYYTNGTNGTNYTNMGNMGNAAY GARATHGARYTNCCNCAYMGNYTNCCNYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNCCNATGCCNAARCCNCCNCCNTTYAAYAAYATHAGYTCNACNTTYGGN GCNGGNCCNATHTTYCCNGAYTCNACNAARCARATHCARYTNAGYAAYCCNACNGTNACN TCNCAYGAYGGNAARTTYCARYTNACNATGCCNATHGAYGAYTAYAARCCNGARGARYTN ACNGTNAARACNCARGAYAARAARGTNATHATHTGYGCNAARMGNGARGTNATGACNGGN GGNMGNAGYCAYACNATGGARATGAAYMGNGARCAYAGYYTNCCNGAYAAYGTNGAYCCN YTNACNGTNAARGCNTTYTTYACNGAYACNAAYATGYTNATHGTNGARGCNCCNTTYYTN MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AAYCARTGYAAYAAYMGNGAYGAYGTNTCNGAR TCNGGNTCNGARAGYMGNTGYATGAARMGNAARACNTCNMGNAARACNTCNGAYGGNTGY MGNYTNGTNGAYGARTCNTTYACNGAYACNGAYTCNGGNYTNTTYGARATHTAYGARMGN ATHMGNAAYYTNGCNATGMGNGARTGYGARTGYGGNAARACNMGNCCNAARTCNGGNGAY GTNGARCCNCCNTAYMGNATHAARGGNAARGTNAAYAARAAYCCNTCNGTNATHAARAAR ATGGARCCNCCNCAYACNMGNAAYYTNGTNMGNATGGAYGTNAAYGARMGNCAYAARATG TAYMGNGARGGNTGGAARGCNMGNCCNGCNATHGGNGAYGAYCAYMGNATHGCNYTNMGN AARGCNACNCARGCNAARYTNYTNMGNCAYGAYGARATHAARATGAARCARAARGTNTAY ATHCCNAAYYTNTAYGTNCCNCCNCAYGARAARYTNMGNMGNGAYGTNMGNTGGCARGTN MGNMGNGCNTTYGARAAYTAYGARATGCCNGAYCAYGGNTTYTAYCAYGAY---ATGMGN TCNGARATHGARCARYTNCARYTNAARACNAARCARYTNTTYTCNGCNAAYAARGARTGG AARGAYAARTGGGAYATHYTNAARAARCARACNGARAAYGARAARTGGGARYTNCARYTN MGNGTNAARGARYTNACNAGYGARMGNGAYMGNYTNAARAARGARAGYGAYTCNTTYMGN AAYTGYYTNMGNCARGAYYTNCAYAARGCNCAYGCNTCNAARMGNGARGCNGARAARGCN YTNTCNGARYTNGCNTCNTCNMGNTCNCARGARAARAARYTNYTNGARMGNYTNAARCAR GAYTAYGCNAAYYTNCAYGARGARAARMGNGCNYTNGARATHCARGTNGARTAYATGAAY TCNMGNAAYYTNGTNGARGTNTCNAARCCNCCNGAYGTNTCNGCNTCNTAYAGYGARGAR YTNTCNGTNGTNAARMGNCARGTNTCNYTNTTYATGGAYGAYTTYAAYAARGARCAYGAR GARMGNYTNTAYYTNGARAGY------------ATGYTNAARAARCARACNCARGCNAAY CAYAGYYTNGARACNAARYTNAARAARAGYCAYGCNYTNYTNAARTCNMGNGAYGARGAY GTNMGNAGYAARTCNAARCARYTNGCNGCNYTNCARTTYCARGTNGAYGAYYTNAARYTN AARYTNGARGTNGARCARMGNMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGNATHGCN GAYGAYTAYAARTGYCCNTCNMGNYTNGAYCAYMGNTTYTCNAARYTNGTNATHYTNGAY AAYAAYCCNAARAARTCNGAYTAYCAYYTNCCNYTNTCNAAYTCNATHGTNACNTCNATG GTNGAYCCNCAYYTNCARAAY------GGNAAYATHGARATHAARGAYCCNGCNTCNTCN AARAAYTCNTCNGTNMGNAARGARGCNAARGARATHYTNAARATHMGNCAYAARAARATG AARAARCAYAARYTNAARAARYTNMGNAARMGNATGTAYTTYGTNTGGMGNAARCARAAR ATGATHMGNAARGGNAARMGNGAYGCNATHTAYTGGAARGAYATHGARGARGTNAARAAR GAYGGNGAYGAYTTYGAYGCNGARTCNTTYGTNAARGARCARYTNCARAARGCNMGNMGN GGNGGNTAYTAYATHAAYGTNTTYCARAAYAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNACN YTNGTNAARTCNGCNGGNYTNYTNYTNYTNATGAGYGTNYTNTTYCAYGTNGTNGCNATH YTNTTYGGNGCNCCNTTYTAYACNTCNGTNTCNGARACNTAYCAYTTYGCNATGYTNATG ACNATHYTNGTNTGYYTNCCNTGYTGYGTNACNGGNGGNCCNMGNYTNGAYAARTGGATH GAYATH---TTYACNGARAARMGNGARCCNGGNATGGARACNATHGCNTAYYTNAGYGCN ATHGGNGCNGTNATHGGNGCNTGGYTNGGNGCNATHCCNATHCCNYTNGAYTGGGAYMGN CCNTGGCARCARTGGCCNATHACNTGYTCNGTNGGNTGYATHTCNGGNTAYTCNATGGGN YTNTTYGTNGCNTCNYTNTAYYTNCCNCAYGARTAYAARACNYTNTTYAARACNAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TAYAARCARTGYACNGAYAARTAYGGNAARCARTTYYTN TCNCAYTAYACNYTNMGNYTNGGNGCNCARGARACNMGNCARMGNTGGMGNMGNCARACN GGNGARGAYCAYGARTCNCAYATHAARCAYGTNGCNTTYMGNGGNYTNYTNTCNYTNACN GARGARGAYGARGGNACNATHMGNCARAARGTNMGNCAYTGYTGYTTYGAYTCNTTYCAR AGYTTYATHGARTCNTTYTAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GAYGARTGGTTYGARGARAARCAYCARCAR ATHGARGCNYTNGAYCARCARYTNAARAARYTNCAYTCNAGYYTNGARAAYYTNACNAAY AAYMGNMGNGARYTNTCNACNACNACNGCNGTNTTYGCNAARAGYGCNGCNATGYTNGGN AAYGTNGARGARCAYACNGCNYTNTCNMGNGCNYTNTCNCARYTNGCNGARACNGARGAR AARATHGARATHGTNCAYAARGAYCARGCNGARGTNGAYTTYTTYACNATGGCNGARYTN ATGAARGAYTAYGTNGCNYTNATGGGNGCNGTNAARAGYGTNTTYCAYGARMGNATHAAR TGYTAYAARAAYTGGAARGAYGCNGARACNATGYTNGGNAARAARMGNGARAAYAARGCN AARYTNGARATGCARGGNAARGCNGAYAARYTNTCNCARGCNMGNACNGARATHACNGAR TGGGARCAYAARGTNGARAARGGNCARGARGAYTTYGARAARATHTCNAARACNATHMGN AARGARGTNTTYMGNTTYGARAARYTNMGNGTNTCNGAYTTYAARACNAAYGTNATHAAR TAYYTNGARGTNYTNATGGAYAAYCARGARAARYTNATHAARTAYTGGGARGCNTTYYTN CCNGARGCNAARGCNATHGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARACNYTNGCNGCNATHCARAGYAGYATHAAYAAYCARAAYCARCARCCNCCNGCN GGNCARGTN---TCNMGNGGNATHACNGAYYTNAARGCNGAYATHTCNTCNYTNMGNAGY YTNYTNYTNAAYCAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARYTNCCNGARTCNGGNACNGCNMGNAAYYTNGTNAAYAAR TGGMGNCARATHGARTCNAGYAGYGGNAAYGCNTCNGCNACNGGNTCNGCNGGNMGNCAY AARGARTTYACNCCNCCNMGNGAYGARCCNMGNATHATGCARAAYAGYMGNTCNCCNMGN ACNCCNAARTCNCCNACNTCNCAYYTNGAYAAYGGNTCNGTNCAYCCNTCNGARYTNCCN GGNCARTAYCARCCNCARAAYGARCCNCAYGTNTTYGARTCNACNCCNGARCAYAAYGCN GAYGCNGCNMGNGARGCNGAYACNGAYMGNTCNAARGGNYTNCCNAARAARAAYCARGCN AARAARATGYTNGCNMGNTTYCARAGYATHCARGCNGARGCNAGYAARGARGCNCCNMGN CCNACNCCNAARAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNCAYGAYCARAAYCARGTNYTNTAYMGNCCNTGYCCNTTYGCNGAYAGYCAR TGYGGNMGNCCNGTNCCNTCNYTNYTNGGNTCNCCNTTYTGYTCNYTNCAYCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARGGNAAY ACNGGNGAYGAYGARAGYTGYCARACNTTYGTNYTNCAYGAYGARGAYCAYACNYTNGGN AAYGCNYTNAARTAYATHYTNAAYAARAAYCCNGAYGTNCARTTYGTNGGNTAYAGYATH ACNCAYCCNTCNGARAGYMGNATHAAYYTNMGNATHCARACNTCNGGNAARCCNGCNACN CARGTNYTNAARCARGGNYTNAARGAYYTNAARCARYTNTGYGGNCAYGCNYTNATGACN TTYGARTCNTCNACNAARTAYTAYAARGARAAYCAYATGGAYGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNYTNGCNATGTGGGAYTTYGARCAYTGYGAYCCNAARAAR TGYACNGGNAARAARYTNAGYMGNYTNGGNYTNGTNMGNACNYTNMGNYTNAAYCARMGN TTYGGNGGNYTNATHYTNTCNCCNGTNGGNTCNAARTGYGTNGCNCCNGCNGAYAARGAY ATHGTNGCNTCNAGYGGNATHGCNGTNATHGAYTGYAGYTGGGCNAARYTNCARGARACN CCNTTYGCNMGNATGAARGGNGAYCARYTNMGNYTNYTNCCNTAYYTNGTNGCNGCNAAY CCNATHAAYTAYGGNMGNCCNTGYAARYTNTCNTGYGTNGARGCNTTYGCNGCNACNATG TTYATHACNGGNTTYCARAAYGARGCNGARATGATHYTNGARAARTTYAARTGGGGNTCN TCNTTYYTNTCNYTNAAYAARGARYTNYTNGAYGTNTAYACNAARTGYCARACNAGYCAR GARGTNGTNTCNGARCARACNAARGTNYTNAARMGNTTYCARGARGAYMGNAARCARGAY CARTCNAARGAYTGGYTNTCNATGGAYCCNGAYGTNGAYGTNTGYAAYCCNAAYMGNCCN ------CCNTCNGAYTCNTCNAGYGARTGYGARGAYTCNGCNAGYAGYGARGARGAYAAY TGYGARGAYGARACNGAYCCNGTNTCNGAYGAYCARYTNCARGGNGAR------------ ------------------------------------------------------------ ------------------------------------------YTNGTNTGYGAYTCNAAR GTNGCNGTNGTNGAYGTNATHGARTGYATHYTNGARGAYYTNAARCCNTGYYTNCCNTCN GGNGCNGARAAY---GTNATGTCNYTNYTNCCNAAYAARGARMGNYTNYTNCARGGNYTN CARTAYGTNTGYGGNCAYAARGARGTNYTNAGYAGYAAYTGYATGGAY---GAYCAYATG CARTCNTTYYTNGGNTGYTAYAARGGNMGNYTNCARAGYYTNGAYGARAAYCARGTNATG ATGCARYTNAARCARAAYCCNAARTCNYTNGTNTGYAARATHGTNMGNACNGARYTNGAY TGYATHCARGARAAYMGNGGNTCNTGYACNAARGAYTTYATHAARGCNGTNGGNGAYACN YTNGAYGCNTTYTTYGGNACNAAYGGNTGYCCNGTNTCNTCNGARACNAARAARGTNGGN AGYACNYTNYTNAGYCAYYTNYTNATHCAYGGNCARCCNGGNYTNAARTTYCARCCNAAR GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARATGTCNAAYYTNMGN CARCARYTNGAR------------------------------------------------ ---GGNAARCCNCAYACNGGNAGY---GCNGAYTCNYTNGAYTCNAAYGARGARYTNGCN ATHAARAAYAARGARGTNATHAAYYTNCAYTCNCARYTNCAYACNTAYCARGTNGAYATG GAYAARAARAAYAARGARYTNGGNGAYAARACNMGNGARYTNGTNGGNTGYMGNGARGAR GTNGARAARYTNAARAARGARYTNGAYMGNYTNAARAAYCCNCCNGTNYTNTGYGARAAR TCNAGYCAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARCCNYTNGARGARTAY GTNGAYGAYTTYMGNAGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNAARGGNAARGCNTCNGARTGGTCNYTNATHAARMGNCAYCCNAGYGAR GAYATGTTYGGNGTNCARATHTGYGGNGCNTAYCCNGAYYTNATGACNAARTGYGCNCAR GTNYTNACNGARACNTGYGAYATHGAYTTYATHGAYATHAAYTGYGGNTGYCCNATHGAY YTNGTNTTYAARAARGGNAGYGGNAGYGCNYTNATGGGNAARGCNACNAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GARGARGARYTNGAYGCNYTNAARTCNGGNAARAARGAYYTNGARAGY MGNYTNAGYCARYTNCARGAYGARYTNGGNYTNAGYMGNGTNAAYGAYGARAARATGGTN MGNYTNAGYGARATHGARGARYTNAARAARGARMGNGARMGNGARGCNGAYATGTTYGCN ATHTCNCARYTNGARACNGARYTNTCNCARTCNMGNGARAARATHGCNGAYYTNAARGAR GARYTNTCNCAYGCNAARGARACNYTNAARTCNCARAGYGCNGGNGTNGTNAAYACNAAY AARAAYTCN---------------------------------------GTNTCNAAYYTN GAYAGYATHGAYATGGGNYTNAARTCNGARAARACNGAY------------------GAR YTNCARTCNAARYTNGAYTTYATHYTNCCNYTNYTNAAYTCNMGNCARATGGCNCARYTN MGNGAYTAYAGYGAYACNTAYCAR------------TCNTAYCARTCNCARATGGARATG GARGGNGAYATGGARATGATGGARMGNAGYGTNTCNAARCCNYTNYTNACNTCNCAYAGY TCNCAYTCNCARAGYCARGAYGTNGAYGAY------------------------------ ---MGNTTYGCNGARYTNGARAARGARATGGARGARYTNMGNGGNAARYTNAGYGARAAR GAYATHGTNATGTCNGARYTNCARMGNTCNAAYTCNTCNYTNYTNGARYTNYTNGAR--- ---------AARAARGCNGAYAAYGGNGAYMGNTTYGCNGTNCAYAARATGGARGCNGAR YTNAARGGNYTNMGNACNGARMGNGARCAYATGGTNGCNGTNGTNAGYGARAARTCNMGN GARAAYTCNTCNYTNAARTCNGARATHCAYMGNYTNATGGAYYTNGTNTCNGCNGGNCAR ACNGCNYTNGCNAARGCNCARCARGAYAAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TTYGGNYTNGTNYTN TGGGARATHTCNMGNMGNGCNMGNCCNTAYTGYGARGARTAYMGNGTNCCNTTYTGGGAY YTNGTNCCNGCNGAYCCNAGYYTNGARGARATGAARGCNGTNGTNGTNGAYAARCARYTN MGNCCNGCNATHCCNAAYAGYTGGACNAARGARCARYTNATGYTNGARATHGARAARYTN ATHMGNGGNTGYTGGGCNCARCAYCCNTCNAAYMGNYTNAAYATHYTNMGNGTNAARAAR AAYYTNCAYGCN---YTNMGNTCNCARCARTCNGARCARATGGARAAR------------ ------------------------------------------------------------ ATGYTNTTYAAYYTNGAYGAYTGGAARAARGGNACNGAYYTNYTNTGYGARGAYYTNAAY MGNAARYTNGTNTTYMGNAAYCAYTTYGAYTGYYTNTCNCARTTYTCNCCNMGNATHTCN GCNTGYATHYTNCAYMGNACNMGNATGTTYAARAARGCNATHYTNGARGCNGGNATGGCN ACNCAYAARAARYTNCAYTAYATHACNTGYAAYTTYGCNGARAAYATHGTNAAYTGYYTN GARMGNCCNYTNGCNAARAARTGYCCNATHCCNGTNGTNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AAYATGATHGARMGNMGNMGNMGNTTYAAYATHAAYGAYMGNATH AARGARYTNGGNGGNYTNYTNCCNAARACNATGGAYCCNGAYTCNMGNCARAAYAARGGN TCNATHYTNAARGCNTCNGTNGAYTAYATHAARACNYTNCARGAYGARCARAARMGNTTY MGNGGNATGYTNGAYGARAARAARAARGCNGARYTNGAYYTNMGNAARGTNYTNATHMGN YTNAAYCARATGAAYYTNGTNYTNAARTCNCAYGGNATHGARTCNGGNGGNYTNGAYGAY YTNGARYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGCARGARMGNATGGARMGNYTNCARGAYGCNYTNAAYGCN TAYGGNCCNAAYTCNCARCAYTTYYTNMGNGAYTCNGTNACNAGYCCNTGGGARMGNGCN GTNGCNGTNAAYAARGTNCCNTAYTAYATHAAYCAYGAYACNGARACNACNCARTGGGAY CAYCCNCARYTNACNGCNYTNATGGAYGCNYTNATHAARYTNAAYAARGTNMGNTTYGCN GCNTAYMGNACNGGNATGAARYTNMGNATGYTNCARAARAARYTNTGYYTNGAYACNGTN AGYYTNCARATGGCNATGGARGCNTTYGAYAGYCAYGGNYTNMGNGGNMGNAAYGAYAAR YTNATGGAYATHGGNGARATHATHGARTGYYTNTCNTCNGTNATGGARTCNGCNGCNAGY CARCAYCCNGARYTNGTNAAYGTNCCNYTNAGYGTNGAYYTNACNYTNAAYTGGATHYTN GAYGTNTAYGAYAGYGTNMGNAGYGGNAARGTNMGNGTNYTNTCNTTYAARGTNGCNATH GTNYTNYTNTGYCARGCNGARYTNGARGAYAARTAYAARTAYATHTTYMGNYTNATHGCN GAYACNAAYGCNTTYGCNGAYCARMGNAARATGGGNYTNYTNYTNCAYGAYTGYATGCAR GTNCCNMGNCARYTNGGNGARATHGGNTCNTTYGGNGGNAGYAAYATHGARCCNAGYGTN MGNAGYTGYTTYGARAARGCNAAYGGNMGNCCNGARATHGARGCNCAYCAYTTYYTNGAR TGGYTNMGNATGGARCCNCARTCNATGGTNTGGYTNMGNGTNYTNCAYMGNYTNGCNAAR TCNGARGARGCNAARCAYCARGCNAARTGYAAYGTNTGYAARGAYTTYCCNATHGTNGGN TTY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ACNAARCAYTCN GCNGAYCARGAYGCNACNGTNACNGAYAARAARTCNAARAARACNAARMGNAARATHGCN GARGARGAYGARGARCCNAARAAYAAYGAYGARAGYGAYGCNAARAARAARGAYAARAAR CARAARTCNGARGGNGARGARACNCARCARAAYGTNGAYGAYGCN--------------- ---GARAARGAYAARCCNGTNGTNAARAARAARAARAAYAARGAYAARGAYAARAARGGN TCNTCNAARACNGCNAAYGAYGARAAYGAR---CCNACNGARCCNAGYGCNATHAAYMGN GCNATHGARTAYYTNAAYYTNTGGAARACNAGYMGNAARTCNTGGAARTTYAAYAARMGN TAYCARACNATGYTNYTNAARGCNATHTAYAAYCCNGTNATHATGTCNGARGAYGAYTTY GARACNATGYTNYTNTAYYTNGARGARAGYAARGGNGGNGCNMGNGARMGNATGAARACN GCNGCNATGGCNYTNGTNAARGARAGYGAYGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GCNGCN CCN---GTNGARACNAAYTAYYTNCCNTGYGAYGAYTTYATGAARTTYCARGAYGCNYTN AARAARYTNMGNYTNYTNGAYGAYMGNATHATHCAYGCNYTNAAYAARGGNATHCCNACN CARTCNTTYAARGGNAARGCNGAYGCNTCNGTNAAYTGYAARCAYATHTAYGAYGAYATH CARACNTCNTAYGAYCARMGNGARAARTCNATHCARCAYTGYATHMGNYTNGTNGGNAAY GAYGTNAARAAYYTNAAYGAYAARMGNYTNCARGAYCCNGAYAAYYTNGAYGTNATHAAR TCNYTNMGNMGNGARCARACNAARYTNMGNYTNATGCARCARGARATGAGYGTNGARGAR GTNGTNAARGAYMGNACNYTNAARGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CCNYTNYTNTCNCAR TGYACNCARYTNGTNCARAARGTNYTNGAYAGYGCNGGNTGYACNAARGAYGAYATHTCN AARGTNATHYTNTGYGGNGGNGGNGCNAARTCNCCNATHGTNAARMGNTTYATGTCNGAY TTYYTNCCNTCNTCNACNYTNYTNAAYTCNGTNCCNGARGAYGARATHATHGCNYTNGGN GCNGCNAARGARGCNGCNYTNYTNGARGGNGAYGAYTGYGARAARGCNAARGTNGARGAR GARCARTCNGTNGTNTTYMGNTCNYTNACNAARGCNATHTGYGTNMGNGTNAAYTCNCCN GARYTNCARGTNGTNYTNCCNCARCARTGYYTNATHCCNGCNMGNMGNCARCAYACNYTN ACNYTNCCNCARTCNCARACNAGYYTNGTNATHGARGTNYTNGARTCNTCNGARCCNGTN ACNTCNGAYAGYGARGCNMGNYTNYTNGCNAARATHGTNYTNMGNGAYYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CAYAARYTNAGYAARMGNGARGARCARATHTAYGAYGCNYTN AARGAYGTNAGYYTNCCNGCNYTNTTYATGCCNTAYAARACNGGNAAYATHTTYAAYCCN MGNGCNCAYCARTAYTTYCAYCCNACNGGNTCNTCNGAYGTNMGNYTNACNCARCCNCCN TCNGTNTTYACNYTNCCNCCNYTNCCNAAYAGYAARYTNTCNGTNGTNAAYYTNTTYGAR YTNAGYAARAAYTTYMGNAAYMGNGGNCCNGCNTGGYTNGTNGARMGNTAYATHCARCAR CARCARCCNTCNCAYGARGAYTAYCCNCARACNCCNGCNCCNACNTCNACNGTNCCNCAR GTNACNAAYACNACNGGNCARACNCCNATHAAYGAYACNGTNGCNACNCCNACNAGYCAR ACNAGYYTNCAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARCCNGTNCCN ATGGTNCCNCCNAAYTAYCCNCCNCCNCARTAYYTNGCNGAYCCNCCNGTNGTNCCNAAY AAYAAYAGYCARGTNAARCCNACNGARCCNCCNGTNTAYTCNTAYYTNGTNMGNMGNGGN TAYACNCCNYTNGAYGCNCCNAAY---MGNCARAAYTCNCCNGCNGGNAGYGTNGCNTCN GGNCARMGNAAYMGNGARGARCCNGAYATHCCNYTNCARMGNGGNGTNGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGYTNGARGAR---AARGTNGCNATGGAR AARAARGTNTCNGCNMGN------CARCCNCCNGGNCARAAYAARAAYGGNAGYGTNTCN TCNGARMGNAARTCNGAYTTYCCNYTNAGYMGNTAYGGNMGNGGNMGNGGNMGNMGNACN TCNAARGCNCCNGAY---------------GCNGCNTAYACNMGNGCNTCNCCNGTNTCN AARGTNGAYMGNYTNTTYGGNGAYAGYMGNCARMGNCCNMGNTTYTGYTAYGAYGAYMGN CARMGNGARGARATHGTNGARAGYGAYGAYGCNTTYGAYGTNYTNAGYTTYGGNTCNMGN AARGGNAAYGCNAAYCAYYTNYTNAAYTTYMGNTTYCCNAGYCARMGNGAYGGNCAYMGN GGNTGYGAYMGNAAYMGNCAYMGNMGNGGNGGNTAYCARAARGGNAAY------CARATH AAR------------AAYAAYGARCARTAYYTNCARGCNAGYTGYCARTTYGTNGTNCAR GAYACNGGNGAYTAYACNAARCARGCNATHGAYTCNGAYGCNTTYGTNGAYTGGAAYATG ATHGARYTNGTNMGNATHTTYTCNACNGARCCNGCNAAYTGYCCNATHTGYYTNGARGTN CCNTTYGCNGGNAARATHACNAARTGYGGNCAYACNTAYTGYTGGCCNTGYATHYTNMGN TAYATHAARYTNGGNGARCAYGAYTCNTGYATHTGYCCNYTNTGYYTNAAYATHGTNGAR TGYAAYGAYYTNAARAGYGTNCARTGGATHTAYGTNCCNGAYTTYAARGTNGGNGAYGAY ATHGARATGAARYTNATGMGNAARGCNAARGGNAGYGTNTTYACNATHCCNAARAAYGAY TGGGARGAYMGNCARGGNAARCCNATGAAYGTNGGNGAYGGNCCNAAYACNAARTAYATG AARATHYTNGTNGCNTCNTGYAAYCARATHCARMGNGARGTNATHGARGCNGARMGNGTN GTNYTNACNCARCARYTNGTNGAYGCNGARGAYGCNGARGTNTGYTTYATHGARATGGCN YTNGARYTNYTNGCNGTNMGNGARTCNTCNYTNACNACNGTNTTYCARGARAGYYTNMGN AARAARAAYAARATHAAYATHCCNGGNYTNAAYTCNAGYGARGCNTAYAARACNGARAAR YTNAGYCARGARGTNAARGAYACNGCNACNAARGCNACNATHAAYGCNGAYGCNTAYGAY GARATHATHGTNGAY--------------------------------------------- ------------------------------------------------------------ CCNGTNGTNGARAAYGCNCAYGTNTTYGAYYTNGTNGARCARGARYTNGAYTCNACNGCN GARGGNATGGARTCNTTYGARTCNGAYGARCCNAGY------------------------ ------------------TAYCARCAYAAYGAYAGYGARAGYTCNGCNTCNTTYGAYTCN CCNCAYYTNCCNTTYCCNCCNATGCCNGAYCARGARGAYAAYTCNYTNCCNYTNACNATH GARGARACNCAYGAYCAYYTNGARYTNCCN---------GTNGAYATGCCNCARCARTTY MGNMGNAAYTTYAGYYTNAAYTCNAARGAYACNTAYTAYTTYTAYCARGCNTCNACNGGN CARCAYGTNTAYYTNCAYTCNYTNAAYGCNCARTGYYTNTCNATGGARTAYGGNTCNYTN GARAAYAGYCCNAGYACNATHAARGCNACNATHGTNGCNACNGARMGNATHACNATGTCN GARGAYGTNMGNAARMGNYTNMGNTAYYTNGAYCAYATHCCNATGTCNACNGARTTYMGN GTNGTNGARYTNAARATHAARCCNCCNGTNGTNAGYAARAARACNYTNAARTGYTTYGAR GCNGCNTTYGARGARAARMGNGTNTCNMGNMGNCARMGNGARMGNGARGARAARMGNMGN GCNGCNAARTCNGARATGGARTAYMGNGCNTCNYTNGGNTTYTAYCCNGAYGTNGARATH CCNYTNGAYAAYYTNAAYCARTTYCCNTCNCAYYTNTCNTGYGAY--------------- ------------------------------------------------------YTNTCN ACNTGYATHGARTTYATHTGYCARGARACNCARGAYTCNGARCCNAGYYTNGARGAYYTN AARMGNYTNGTNTTYGARCARTGGYTNGTNTCNGAYYTNTCNGARATHGGNACNCCNGTN ATHCCNGAYGARGTNYTNACNAGYGAYAARCARGARYTNCCNCAYGTNTAYCCNYTNCAR ATGATHTCNATHYTNGAYGTNTCNATGCCNYTNTAYGGNCARATHMGNAARYTNGARGCN AARGAYTTYGAYGCNAGYATGATHACNTAYTCNGAYACNCCNTTY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYAAR ATHATHYTNTAYAGYTAYTTYMGNAGYTCNGCNAGYTGGMGNGTNMGNATHGCNYTNGCN YTNAARGAYATHAARTAYGARAGYGARGCNGTNCAYYTNGTNAARGGNCAYCARAARTCN GAYGARTAYAARGTNATGAAYCCNATGGCNCARGTNCCNACNYTNAARATHGAYGGNYTN TCNYTNAAYCARTCNYTNCCNATHATHGARTAYYTNAAYGARMGNAAYCCNGARCCNCCN YTNYTNCCNAARGAYYTNGARGGNMGNGCNAARGTNMGNGCNATHGCNGARGTNGTNAAY AGYGGNATGCARCCNYTNCARAAYYTNTCNGTNYTNCARAARGTNGGNGARACNAARATH GARTGGGCNCARCAYTTYYTNTCNAARGGNTAYCARGCNYTNGARGARATHYTNAARGAR ACNTCNGGNAARTAYTCNTAYGGNGAYCARGTNACNYTNGCNGAYYTNTGYYTNGTNCCN CARGTNGCNTCNGCN---GCNMGNTTYAAYATHGAYATGTCNAGYTAYCCNACNGTNTGY MGNGTNAAYAARGCNYTNGARGARYTNCCNGCNTTYAARCAYGCNGAYTTYMGNMGNCAR CCNGAYACNCCNGARGAYYTNMGNATHGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGTCNGAYAARYTNAAYACNMGNGTNATHCARGTNACNAAY ATHGCNCCNAGYTGYTCNAARGAYCARYTNMGNACNYTNTTYGGNTAYYTNGGNMGNATH AARGARYTNCARATGTTYCCNCCNGAYGGNGCNGAR---GGNGTNGTNACNGCNMGNGTN GCNTAYATHGARTTYGARGAYTCNGTNACNACNGGNGTNGCNYTNCAYYTNAGYAGYACN GTNTTYATHGAYMGNGCNATHATGATHGTNCCNGTNATGGAYGGNAARATHCCNGAYGAR AGYTCNGCNYTNCARYTNACNCCNTCNGCNGTNGCNGGNATGYTNCCNGGNCARCCNACN TGGCCNGCNAAYGTNGTNTCNCARGTNACNGGNYTNGGNGCNAAYCARATHATHATGACN AAYGAYCCNMGNYTNACNTCNYTNGGNYTNCCNCARTAYCCNCCNYTNCCNGCNACNACN GAYCCNAGYAARATHGARGARATHMGNMGNACNGTNTAYATHTCNGAYYTNGAYCCNAAR GTNACNCCNGARATGYTNYTNTCNTTYTTYTCNCARACNGGNGARATHAARTAYATHMGN ATGGCNGGNGAYGARAAYGGNCCNACNMGNAGYGCNTAYYTNGARTTYACNGAYCARMGN TGYATHGCNCARGCNYTNAGYTAYAAYAAYGTNGTNTTYCARGGNMGNACNGTNAGYGTN AARCAYGCNACNACNAGYATHGTNAARCCNTCNCCNAARTCNGARGCNTCNCARMGNGAR ATHGAYGAYGCNATGAARAARGTNAARGARGCNTCNAARYTNATHTCNGCNGCNGCNAAY AGYGAYMGNGAYGGNTCNMGNTCNCCNTCNMGNMGNMGNTCNAARTCNMGNGGNMGNAGY MGNTCNMGNTCNAARTCNMGN---MGNMGNTCNMGNTCNMGNTCNMGN---GGNMGNMGN MGNMGNAGYMGNTCNMGNTCNMGNAARMGNTCNMGNTCNMGNMGNMGNTCNCCNMGNMGN TCNMGNACNCCNCCNMGNMGNMGNMGNTCNMGNTCNMGNGGNMGNGTNCCNCCNCCNGCN CCNCCNGTN------------------TCNMGNMGNMGNTCNMGNACNMGNTCNCCNGTN MGNMGNMGNMGNTCNMGNACNMGNTCNAARTCNAARCARMGNMGNTCNMGNACNCCNCCN AARTCNTAYAGYMGNMGNAGYMGNTCN--------------------------------- ------------------------------------------------------------ ------MGNGARMGNMGNGARMGNMGNGARMGNAARMGNAGYGTNAAR------GGNMGN TCNCCNAGYCCNCAYAARTCNAARAARMGNAGYGCNAGYCCNMGNAARMGNAGYMGNTCN AARACNCCNAGYMGNMGN---AARAARMGNMGNCAYTCNMGNTCNACNTCN---MGNAAR MGNTCNMGNTCNMGNAGYGGNTCNMGNCAYAARTCNMGNAARGAYAARAARMGNAGYMGN AGYMGNGAYMGNAARCAYGAR---AGYAARAARAARAGYAAYMGNGAYAARGAYGARAAR AARAARGARAGYGGNTCNTCNAARCARATHAARMGNGAYTAYGAYGARGARGARAARGGN TTYGGNAGY---GAYGARGCNAGYGARGARMGNGARAAYAGYGARGCNGCNGGNTCNGTN GAYTCNGCNAAYGARCARCCNCCNGTNYTNGAYAARGAYACNGAYCAYCARACNGTNGAY ATGGAYATGAGYGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GCNTCNACNGGNGGNTTYAAYTTYGGNCAR GCNGCNCARCCNGCNTCNAAYCCNGCNGGNGGNTTYAAYTTYTCNGCNCARCCNCCNACN GCNGCNGCNTTYGGNGGNTTYAAYTTYAAYGCNGGNGCNGGN---GCNACNCCNTCNTTY AAYTTYAGYGCNACNCCNGGNACNCCNAAYATGTTYACNCCNCARACNCCNGGNTCNGCN CAYMGNCCNMGNGCNACNGCNMGNMGNCCNGTNMGNMGN---------CARATHGCNCAY ATGATHGCNTTYATHGAYCARGARGCNTCNGARAARGTNGARGARATHGAYYTNAARGCN GARGARGARTTYAAYATHGARAARGGNMGNYTNGTNCARCARTCNMGNGTNCARATHATH GAYTTYTAYGAYAARAARGTNAARAAYGTNGARYTNCARAARAARATHCARAGYTCNAAY ATGCARAAYAAYGCNMGNYTNGARATHYTNMGNMGNAARGARGARTAYGTNMGNGARGTN YTNGAYGARGCNMGNGARCARYTNMGNAARGTNGCNAARGARAAYCCNGARGARTAYAAR CAYYTNYTNATGAARYTNGTNATGCARGCNYTNGTNMGNYTNATGGARTCNAARGTNACN ATHMGNTGYMGNAARGARGAYGTNCARATGGTNAARAAYGCNATHCCNTCNYTNGARAAR GARTAYAARCARYTNYTNCARGGNAARTAYAAYYTNGARATGATHGTNGAYGARAAYAAR TTYYTNTCNCARGARATHTGYGGNGGNGTNGARYTNCAYGCNATGAGYGGNAARATHGTN GTNGTNAAYACNYTNGAYGARMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNAAYCARGTNACNATHAAYGGNCARACN TCNTTYGTNYTNGTNGAYGCNAAYAAYAARCCNATHCARYTNCCNCARGGNATHCARGTN ATHAAYYTNCCNCAYCARCARATGTCNGGNCARTCNATHCARATGCCNGGNGGNGAYACN GGNGAYGARCCNYTNTAYGTNAAYGCNAARCARTAYCAYMGNATHYTNAARMGNMGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARYTNGAYGTNATHYTNACNACNGGNGGNACN--------- ------GGNTCNCCNMGNGAYGTNACNCCNGARGCNACNAARGCNGTNYTNGAYAARGAR GCNYTNGGNATGGCNGTNTCNATGATHAARGGNTCNYTNMGN------------------ ------------------------------------------------GGNAARCAYTCN TCNTCNAGYTCNAGYAGYTCNTCNTCNAGYGAYTCNTCNGAYGAYGAYTGGAARCAYYTN CCNAARCAYGAYAARAARATGMGNAARAARTGGAARAARCARMGNMGNAARGGNATGATH CCNCAYAAYCARYTNGCNCCNTGGCARGGNGGNCCNGCNTGGTAYCCNCCNGTNAARCAY GGNAARAARGGNAARGGNCAYAARGGNGGNAARCCNGGNGGNGGNGCNTAYCCNGCNGGN GGNGCNGGNGGN------GCNTAYCCNGCN---GGNGGNGCNTAYCCNCCNGGNGCNCAY CCNCCNGGNCARCARCCNTAYCCNGGNCARCARGCNTAYCCNGGNCARCARCCNGGN--- TTYCCNGCNTAYCCNCCNCCNCAYGGNGGNTAYCCNCCNCCNCARGGNGCNTAYCCNGGN GGN---CCNCCNGGNGGNTAYCCNGCNGGNAGYTAYCCN------------------GGN GTNGCNCCNCCNCCNGCNCARTAYGCNCCNCCNACNGGNGCNTAYGGNGGNCAYGGN--- GCNCCNTCNGGNCCNTTYCARGCNCCNCCNGGNGGNGCNTAY------CCN------GGN TAYCCNCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GARTCNGAYGAYMGNCCNAAYACNAAYYTNTCNTCNTCNACNYTNACN GGNCAYCCNACNTCNACNMGNCAYGAYTCNTCNTAYAGYGGNTAYGARGGNCCNAAYATH TCNYTNYTNAARYTNCARAARAGYACNTGGCAYACNGARATHGARCCNCCNATHTAYGAY TAYGARMGNYTNAARATHACNAAYTTYGAYYTNCCNAARGAYGTNGAYACNAAYCAYYTN GARATHCAYYTNAAYAAYGARGAYTTYGARGARYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNTAYGTNTTYTTYGAYGARATGTAY YTNMGNAAYACNMGNATHGTNYTNGTNGAYTTYATHATHTCNGGNGTNYTNACNYTNTTY TGGATHATHTCNTCNTCNGCNTGGGCNGCNGGNYTNAAYGAYGTNAARYTNTAYACNGAY CCNTAYGAYGGNGGNATHTTY---CARACNGTNYTNGARTGYCARAAR---AARGGNGAY TGYGTNACNGAYAGYGARGGNAAYTTYGCNAGYYTNAAYGTNTCNATHATHTTYGGNTTY YTNAAYTTYATHGTNTGGGTNGGNAAYYTNTGGTTYYTNTAYAARGARACNCCNTGGTTY AARGTNCARGCNAARCCNCCNACNCARCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TAYMGNMGNATHGCNATHGGNCARAAYYTNTCNYTNCAYGTNATH ATHGAYCCNYTNCARCCNTCNAGYYTNCCNGGNTGYMGNATHYTNGGNGCNGARTCNGCN GTNGCNCCNYTNMGNGARAARYTNAAYGTNAAYYTNCAYCARTGGGAYYTNGAYMGNTCN YTNYTNAAYAAYYTNCARGARGTNYTNGARATHGAYTTYCCNACNCCNTCNGAYACNAAR AARGARGARYTNAGYGTNGAYTGYGGNATHTGYTAYTGYAAYCARYTNGGNGARGARATH CCNGAYGTNYTNTGYCARCAYTCNMGNTGYAGYCARGCNTTYCAYTAYACNTGYYTNTAY GARTGGYTNMGNAAYTCNTCNTGYCARCARAGYTTYAAYTAYATHTTYGGNGARTGYCCN TTYTGYAGYAARCCNATGMGNGTNAARATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TCNTCNGGNYTNGGNTAYGGNTCNGCN ACNGARAGYGARGGNGARAAYGAY------GARAARGAYGARGAYTCNGAYAGYGAYYTN GARGARMGNATHMGNMGNAARAARGCNGARTTYGCNAARMGNCARMGNATHTTYAGYGAY GTNGARGAYAGYGAYAGYTCNCCNYTNAARMGNGTNGGNMGNGAYMGNAGYAARGAYAAR GAR------AGYGTNCAYTCNGTNAARGAYGGNAGYGARAARGTNGAYMGNMGNCAYAGY GAYMGNTCNGAYMGNMGNAAYAGYAARGAYACNAGYGTNACNAARGGNAAYCAR------ ------CAYAGYMGNTGGGAYTCNAARYTNAARGTNGAYGCNACNGCNGGNMGN------ ------------------GARAARGARMGNCAYAARGAYACNAARAGYGTNMGNCAY--- ------------------------------------GAYAARGTNTCNGGNCCNGTNGGN GAYGAYCCNAARACNGTNGARAARCCNAARGTNAAYCCNGTNGTNAARAARCARGAYAGY GAY---------------------------------------AGYAGYAGYAGYACNGGN AGYAGYAGYGAYTCN---TCNAGYTCNGAYTCNAGYAGYAGYGGNAGYGAYGARGAYGGN GARGGNAGYAGYTCNTCNACNTCNTCNTCNTCNTCNTCNTCNTCNTCNTCNTCNCARMGN GGNGARTCNGARAARTCNAARTCNAARCCNAGYGCNMGNGAYTCNGTNAARAGYMGNCAY ATHGAYGCNCARAARTCNGAYAARATHAAR------------------AGYAAYGTNAAR GARGARMGNGARATHMGNAARGAY---AGYCAYTCNAGYAARAGYGGNAARAARGAYCAR AAR---------GARAARGARMGNAARACNTCNYTNCARATGGARMGNGAY--------- ---GTNAGYATHAARAAYTCNAARTCNAGYGARAARGGNMGNTCNCCNCAYMGNGARMGN GTNGARTCN---TCNAARGAYAARGARAARYTNAARAARCARGGNAARGARAARMGNAAR MGNAGYTCNAGYTCNAGYGAYGARACNAARAARGARTTYAARAARAARAARCCNAARTCN GAYCAYAARAGYAARACNMGNGAYAARGARGARGCNMGNTCNMGNGAYCAYGGNGARGAY MGNMGNMGNAGYMGNTCNAARGAYMGNAAYAARMGNMGNMGNAGYMGNAGYTTYTCNMGN GAYGARMGNGARMGNMGNMGNGARMGNAGYAGYTCNMGNGGNCARGGNAARMGNCAYMGN AGYGARAARMGNMGNGARMGNAGYMGNAGYGAYTCNMGNMGNMGNCAYAGYMGNGAR--- MGNMGNAGYATHAGYMGNGAYYTNACNMGNGAYMGNMGNAGYMGNAGYACNGAYMGNAAY AARGAYAARACNMGNAARMGNAGYMGNAGYGTNGARAARTCNTCNAARYTNGARAARTCN TCNMGNAARTCNAGYGGNGGNGAYACNAGYMGNGARAARAARAARAARMGNGCNCARTCN AARAARAARTCNAARTCNAARGAYGAYGTNGAYGTNTAYMGNAARGAYGGNAARACNGCN AARAGYAARMGNCAYGGNGGNMGNTCNMGNTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------MGNATH AAYAARAAYGARGAYGAYCCNACNGARGTNAARYTNYTNYTNAAYGCNGCNMGNACNTCN TTYACNAARTAYATHGAYMGNYTNGCNCAYTTYTTYCCNGTNTCNYTNYTNCCNGTNCAY GTNTCNGTNMGNGARMGNTCNTCNYTNYTNMGNAARYTNGARMGNCCNYTNACNCAYATH YTNAGYAAYAGYCCNYTNCAYTCNAARGGNMGNYTNATGTCNTCNCARGARGTNATGGGN AGYYTNCARCAYCAYATHYTNGAYYTNACNCARMGNYTNCAYGCNGCNGARAARGARMGN MGNCAYYTNYTNGCNAAYYTNAAYGAYYTNAARCARCARATHGGNGAYGAR---YTNTCN ACNCAYAGYGCNGTNAGYAAYCARCCNTCNGGNAARGGNGCNAARTAYGTNGCNATGGAY AARTTYGARAARGTNTGYACNGARYTNTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GGNGCNATHGTNTTYAAYCARATH ACNACNGCNTTYGTNAAYCCNCARAAYYTNAARCCNGAYGCNCAYATHGGNMGNATGGCN TTYTTYTCNCARGAYGARGTNATHGAYAARGTNCCNTCNATGTTYYTNGTNYTNGCNGTN TGYTGYYTNGGNATGAAYATHGTNAGYTTYYTNYTNGTNMGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ACNGCNACNCARTAYATHGCNCCNYTNATGGCNAAY TTYGAYCCNTCNACNAGYACNACNTCNAAYGTNTAYTAYYTNAGYGARGARGAYATGYTN ACNGTNGARTGGMGNGAYGTNCARYTNCARGAYCARYTNCCNYTNGGNAAYTTYACNTTY CARACNTCNYTNTAYCARAAYGGNAGYATHAGYTTYGTNTAYAARGAYATHCCNTCNAAY GCNCARGGNATHTCNGARGAYAAYCAYCCNGTNAARGTNGGNYTNTCNGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARACNGARGTNTCNTCNTGGYTN TCNCARATHTTYGGNCARGARTCNGTNCCNGAYTTYGARYTNAAYGCNCARACNATHCAY YTNYTNCAYCARYTNYTNGARATHAGYCARTTYAAYGARAARAARGAYCARYTNTAYYTN GARGAYYTNAARAARAARACNGARGARTAYAAYGCNGAYGCNCARMGNGTNAGYAAYATH YTNGAYAARYTNTCNYTNGGNTCNAAYAAYTTYACNTCNTCNGCNACNGCNTCNGTNCAR GCNYTNGCNAARACNGGNGCNYTNYTNAAYATHAARGAYGCNTCNGAYACNAGYTAYATG YTNTCNYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTNYTNYTNTCNGTNGTNGTN TCNACNAAYGCN---TTYGTNGTNTTYTCNACNGGNAAYTGYCCNAAYATHGARGTNACN AARAAYTTYAAYYTNACNGCNTAYGCNGGNMGNTGGTAYAGYTAYGARAAYTTYGAYGCN CCNTAYCARTTYGGNATGTCNTGYGTNACNGCNACNTAYGAYATHYTNCCNGGNAAYMGN GTNTCNGTNYTNAAYGARGGNTAYMGNGARATHMGNGTNTTYGGNATHAGYYTNTAYMGN MGNGAYGTNACNGCNAAYGGNYTNGCNMGNGTNGTNAAYTCNGAYGAYCCNGCNMGNYTN TAYGTNAGYTTYGGNGAYTTYAGYTTYGGNGGNGGNCCNAARGCNAAYTAYATGGTNGTN GAYACNGAYTAYAARACNTAYAGYYTNGTNTAYTCNTGYAGYAGYYTN---TTYATHCCN TTYAARYTNGARGGNGCNTGGATHYTNACNMGNGTNMGNGGNGCNMGNCCNAARAAYATH TTYGARYTNGARAAYAARYTNGCNTCNMGNGGNATHAAYATHAARAAYTTYAARATGGTN GAYAAYAGYGGNTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNMGNATHMGNMGNGTNGTNGGNGGNCARCCN YTNACNMGNGGNCARTGGCCNTGGYTNGTNTCNYTNCAYTAYYTNAARCCNTAYCCNTAY AARAAYYTNCARCARYTNGAYCAYYTNTGYGGNGGNTCNYTNATHCAYCCNMGNTGGGTN YTNACNGCNGCNCAYTGYGTNGGNTAYCARGARGGNTCNCCNGAYYTNAAYGAYCCNGCN AAYTGGYTNGCNGTNYTNGGNGARTAYAAYMGNYTNGTNAGYGARGAYACNGARCARAAR YTNGAYGTNCARGGNATHATHGTNCAYCCNAAYTTYTCNYTNTTYCCNAAYYTNACNTCN GAYATHGCNYTNYTNAARYTNTCNMGNCCNGCNATHCARACNAAYACNGTNAARACNATH TCNYTNGAYACNATGMGNCARYTNTCNGAYGGNGARGARTGYCARGCNGCNGGNTGGGGN CARTAYTCNGAYGAR---------GCNTCNCARTTYGGNAAYGGNACNYTNATHCCNCAY GTNGTNACNATGMGNAARGTNACNGAYCAYMGNTGYGTNAGYACNTAYMGNGAYYTNTGG CCNGTNGTNGAYGARMGNTCNATGTGYTTYCARTCNGARGGNAAR---GAYACNTGYCAR GGNGAYTCNGGNGGNCCNYTNGTNTGYACNGAYGCNTCNAAYMGNCCNACNYTNACNGGN YTNGTNTCNYTNGGNATGGGNTGYGCNATGGCNGAYTAYCCNGGNGTNTAYGCNMGNGTN GCNACNTAYMGNGARTGGATHYTNGAYACNGTNGARGCNCAYACNGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGTGYAGYMGNMGNGARCCNGCNMGNTTYYTNATHCARGGNYTNGAY GCNGCNGGNAARACNAGYATHYTNTAYAARYTNAARYTNGGNGARATHGTNACNACNATH CCNACNATHGGNTTYAAYGTNGARACNYTN---ACNTAYGGNGGNATGGARTTYACNGCN TGGGAYYTNGGNGGNMGNGAYAARATHMGNCCNYTNTAYMGNCAYTAYTAYGCNAAYAGY GCNGGNYTNATHTTYGTNATHGAYAGYACNGAYACNGAYMGNYTNGAYGARGCNYTNGAY GARYTNGAYMGNATGGTNYTNCARAAYGARGAR------YTNCCNGTNGTNATGGTNYTN GCNAAYAARCARGAYYTNGARAARGCNATGGAYCCNGCNCARYTNGARGCNAARATHAAR GARAARTGYTCNAAYGGNACNGCNTCNTCNTAYTTYGTNATGCCNTGYAGYGTNTTYGAR GAYAAY------AGYATHAAYAGYGCNTTYCARTTYTTYGCNAARCARYTNAARYTNAAR CARGARGGN---------------------AARYTNGCNGCNGGNYTNATH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AGYGCN AARGAYYTNGAYACNATHATGTCNCARGGNYTNGGNYTNMGNTAYGCNTTYATGGGNCCN TGGGARACNGCNTAYYTNAAYGCNGARGGNATGCARGTNTAYGGNGARMGNTAYGCNGAY ATGATHYTNAAYATHCARAARAGYTTYCARAGYCCNGTNAARATGGARGGNGARACNYTN GAYMGNATHCARGGNGARATGGARGARYTNGCNGGNCCNGTNGARGAYATHCARAARMGN MGNCARTGGMGNGAYMGNMGNYTNACNGGNYTNGCNAARYTNAARGCNGAYATGGAYAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNACNTGGTGYMGNAAYTTYGTNGCNACNMGNACNYTNMGNCAR GARGARGARGARGGN---GARCARTCNGAYACNGAYAGYTCNACNAARMGNAARGTNGTN GAYGTNGAYACNAGYATHMGNTAYYTNAAYAGYAARGCNTTYGTNGARGGNTAYGGNGAR AARCCNATHTGGTTYCAYTAYMGNMGNAAYTTYAARGGNMGNATHGTNCCNCCNACNMGN AARAARTGYATHMGNGCNGGNGARGTNACNACNGCNAGYCCNTGYCCNGTNTGYMGNGAY GARTAYYTNGTNYTNGAYGCNAARAAYACNAARYTNYTNGARCARTTYATHTCNCCNTAY ACNGGNGAYATHTAYGAYTCNATGAARACNGGNYTNTGYCARGARCARCAYMGNAARYTN ACNGTNGARGTNATGAARGCNTGGGAYCARGGNTAYYTNGARATGAARGTNCCNGTNMGN ATHTAYAAYTAYGAYGAYTAYAARAGY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TGGAAYCARACNMGNAGYATHATHGAYGAYGARMGNYTNAARGGN YTNMGNAARGTNGARATHAARTCNCARTCNACNCAYTTYTGGMGNACNCARGARGGNYTN CCNAARACNTAYYTNTCNACNATHGARGCNYTNTAYTAYTTYYTNAARGARTTYCAYACN ATHTTYYTNGAYCCNGTNTAYAARCAYGARTAYGAYAAYYTNYTNYTNYTNTTYMGNTAY YTNTAYGARAARGTNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNTTYAARAGYGAYYTNAGY TTYGAYAARYTNTAYCCNAGYTCNAAYTCNGAYTTYYTNMGNCARCAY---MGNCAYATG GARTCNGAYAAYTCNTCNCARAARTTYTCNGGNTAYATHCCNGTNGARCARYTNGARATH AGYCAYAGYMGNAGYAGYGGNCCNGGNGGNCARAAYGTNAAYAARGTNAAYAGYAARGTN GARGTNMGNTTYCAYYTNAAYACNGCNTCNTGGATHCCNGAYTGGATHAARCCNAARATH TCNTCNCARGARCARAAYMGNATHACNAARGAYGGNTTYYTNGTNATHAARTCNGAYATG ACNMGNAARCARATGYTNAAYCARGCNGAYTGYYTNCARAARYTNMGNAAYATHATHTAY MGNGCNTCNATHGTNGARGARGGNCCNACNGARGARGARAARAARATHAARGARCARMGN ATGATGAARGCNAARTCNGGNATHYTNAARGARAARMGNMGNAARTCNYTNYTNAARAAR TCNMGNTCNAAYCCNGAYYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARTTY CAYGGNYTNTTYCCNYTNGCNTCNTGYYTNAAYCAYTCNTGYTTYCCNAAYGCNMGNATH GARAGYGTNGARGTNGARGCNYTNCCNGGNATHCARGTNGTNGCNGTNMGNGAYATHAAR GCNGGNGARGARGTNTTYGTNTCNTAYGTNGARCCNYTNCARGAYMGNGARGARMGNMGN AARACNYTNTGGAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CARGCNYTNTGYGCNYTNAGYAAY ATGGCNGAYGGNCCNTCNTGYAARGCNTAYATHATHGGNAARACNGAYGARATHAAYTCN GTNGTNAARTAYYTNCARTTYCCNGAYAARCARYTNCARYTNCCNGCNATHCARTTYGTN AGYAAYYTNGTNGAYACNMGNGAYGAYGAYTTYGGNCCNTTYCCNMGNGCNGGNTCNTAY CARMGNATGYTNCARYTNAARACNYTNGGNGTNCARAGYYTNYTNGARAGYYTNATHGGN ACN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNCARGGN TTYGAYGCNTTYGGNGAYGTNYTNGCNCCNATGAAYAARTCNCCNACNCAYCARGCNCAR GTNACNCCNGCNGGNMGNCCNYTNGGNGGNGAYYTNGAYTCNTCNYTNGCNAGYYTNGCN TCNAAYYTNAAYGTNAGYGGNGGNACNGGNCARYTNAARAARGAYCAYCARTGGCARCCN AARGGNGARAAYAARYTNACNGGNGGNCARTCNTTYCARMGNCARCCNATHGCNGCNTCN ACNACNAAYCCNGCNCCNACNCARTGGGGNCARCCNGGNTTYCARCARCCNAAYATG--- ---ATGGGNGCNCCNGGNGGNCCNATGATGTAYGGNCARCCNATGGGNATGCCNATGGGN CARCCNATGATG------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY CAYAARMGNCAYCCNMGNAAYTAYGGNGGNGGNGCNGAYYTNGCNMGNGTNAARGAYAGY ATGAARACNATGMGNGARAARGARAARGARMGNCCNGGNACNATGAARCCNYTNGARATG GTNATGACNGGNMGNGARMGNAARAAYCAYGARCARTGGAARCARGARMGNGARMGNTAY GAYAAYGARMGNATHCARMGNCARYTNGGNGARGGNGGNACNTGGAARMGNGARTGGGAY CAYAAYAARGTNGTNYTNGAYTAYGAYGAY---------CAYCAYTCNMGNATGGARCCN GCNAARMGNCCNGCNGGNMGNATHGGNAGYGGNMGNTTYGAYMGNGGNGAYMGNGARGAR CAYCCNMGNTCNGCNAGYMGNGARGGNAARGGNGGN------------------------ ---------------------------------------------------------GCN TCNCCNCARCAYCARCCNTCNCARAGYGGNGGNGGNCARAGYCAYCARACNTCNCCNCAR AGYCCNCARCCNGGNGAYAGYAARCCNTCNMGNGGNMGNGGNMGNGGNMGNGGNMGNGGN MGNGGNMGNGGNTCNAGYCARGGNAAYACNCCNGGNGGN---GAYAARTCNCCNMGNCCN MGNACNTGGTCNGGNGGNGAYGAYMGNTTYGTNGARTGYCARAARGARATGYTNGTNGTN AARTTYGAYAAYACNGTNGGNGAYAAYACNGTNGARGTNGARTAYGARAAYGGNGCNCCN YTNTCNCCNACNCCNTCNTCNAARTCNTCNGGNTCNACNCCNGGNMGNGGNCCNACNGGN MGNACNCCNAAYCAR---GGNAAYGCNAAYAGYMGNTCNAARGGNAAYMGNCCNGTNGAY CARAARMGNGARAARGTNGGNMGNGGNAARGGNGGNAGYGGNMGNACNTCNAGYCARTAY CAR---------------CARGTNGAYGCNGARTTYGAYMGNCCNGCNAAYCAYMGNCAY TCNTAYGAYGGNTCNAARGTNMGNACNTCNTCNCAYTCNCARAGYCAYGGNGAYAGYGAR GARTGGGARGAYTGYACNGARTCNTCNGGNGTNYTNGARGAYGAYGAY---------ATG ATGGAYGGNGCNCARAAYYTNCAYYTNGARTGYCARYTNAAYCCNGAYGCNCCNGARTTY YTNCCNACNTCNCCNGAYTTYYTNAARACNCCNCCNGGNCAYGTNAARGTNYTNAAYTGG GCNGGNAGY---AAYAGYCCNACNTCNCCNCARTCNAAY--------------------- YTNAGYCARCCNTAYTCNCCNGCNYTNTCNCCNMGNCARCARGARAAYATHTCNAGYCAR ---------------TCNTCNATHTCNTCNCCNGGNTCNTCNGTNTCNACNAARGCNGTN MGNAARMGNGARCARATGGAYGCNATGCCNGARCCNGAYGARCCNATGCCNCCNCCNTTY YTNYTNGARGCNGCNAGYAARAARCARTCNAAYGGNGAYAARAARGARGCNAARGARGCN GARGARAARCARGARGTNAGYAAYAGYGAYAARGARGARATGGARGGNGAYGARYTNGAY GARGARMGNTTYGARGAYTCNGTNGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNGAYTCNAAYGCNCCNMGNCCNGARGCNGTNTAYYTNMGNMGNGAR AARCARCARCCNCCNACNYTNACNGCNTCNAARCAYCCNCAYGGNGCNAGYCCNACNAAY ACNAGYCAYCCNCAYACNGGNCARCCNMGNCCNYTNMGNTAYGGNAAYGAYAAYAGYAGY GTNAAYMGNCARGCNMGNACNCARAGYACNMGNCCNGAYCCNATHCCNGGNCARCCNTAY GCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CCN CCNAGYTCNYTNGGNCARMGNYTNGAYGTNGGNAGYYTNTTYGARAAYGCNAARTTYTCN AARGCNCCNGAYTAYAGYAARCCNAGYGGNGAYTCNTAYATHACNCARTAYAAYCARGCN GCNACNGARTCNATHAARAAYACNATHGGNATHGGNAAYTCNTCNMGN---CCNCAR--- ---------ATGGGNATGTCNCCNCARAAYTCNACNAGYTCNYTNGGNYTNTCNAAYYTN GGNCARAAYTCNGCNCARGTNCARGGNAGYTCNGTNYTNTCNCCNYTNCARCARTCNAGY TCNCARAAY------TCNATGCCNCAYGCNATHGCNCARYTNTCNCARATHTCNCARCCN TCNTCNCARTCNGCNAGYATGTCNCARATGGGNATG------------ACNTCNCARACN AGYCARGAYGCNAAYACNCCNGCN------------------------------------ ---------CCNCARCARTCNMGNATHCCNGCNGTNGTNCARCARCARCARAGYYTNCCN CARACNAGY---------------------ATGACNAAYATGCARCARMGNCCNAARCCN CARMGNTCNAARYTNCCNCCNCCNTCNAARATHCCNTCNACNGCNGTNGARATGCCNGGN CAYATHCCNMGNAAYCCNCARYTNGAYGTNCARTTYGGNYTNGAYTTYGGNACNGARCCN TCNGTNCARTTYGGNTTYGGNGGNAAYGGNGAYAAYACNGCNGTNACNAGYTCNTTYTCN ACNTCNACNAAYGGN---TCNACNGTNATHTCNAAYCAYYTNAAYCARGGNCAYGTNAGY CARTCNGCNGGNGAYGGNAAYTCNGTNTCNACNATHATGCCNTCNCCNTCNGCNGGNTCN TCNAARGTNCCNTCNGGNATHGARCCNCARGTNTCNAAYMGN---CARGGNGTNTTYCAY AAYTCNGTNTAYTCNTCNCCNCARCARAAR---GAYAGYCARACNYTNGAYMGNGAYCAR AAYAARYTNAAYGARTCNATHCCNTTYYTNCCNTCNCARYTNGARMGNAARTCNAGYCCN ---ATGCCNGCNCARMGNCCNGGNCARACNAAYCARAAYYTNAGYTCNGGNTCNATGGCN TCNAAYAARGAY------TCNAAYAGYGGNGTNACNAAYAAYTAYTCNTCNGCNAAYGGN TTY---CCNTCNTCNTCNTAYCCNAGYCAYACNAARAGYYTNATHTCN------CAYTCN GCNAAYTCNCARCCNTCNCARACNTCNTCNTTYCCNGGNCARTAYCCNGTNAAYCARTCN TCNTTYCCN---ACNGGNCARAGYCARTTYCCNGCNCCNCCNAAYACNACNCCNTTY--- CCNTCNGGNCARTCNGCNCARTAY---------AAYTCNAGYCCNTCNCARAAYCARTAY TCNTCNGGNCARAAYCARTTYTCNGTNGGNACNTCNACN---------YTNTCNCAYCAR AAYCARTAYTCNAGYGGNCARAAYAAY------TTYGGNGGNGTNCCNTCNCARTAYTCN AGYTAYCARAAYAAYAGYTCNTTY------------CCNTCNCARTCNAAYTTYCCNCCN AARCARAAYGGNAGYTCNGGNTCNGGNYTNTAYCCNACNTCNACNCARTCNGGNGTNTCN TCNTAYACNTCNCARTCNAGYTCNTAYCARTCNCCNTCNGCNGGNTCNTAYCAYTCNTCN MGNGAYGTNCCNTCNAAYATGCCNGCNAGYACNCARTCNAGYACNGGNATGTCNTTYCCN AGYCARCCNCARAGYTCNAAYYTNAARCCNGCNGCNTCNCARGGNAAYTCNAGYTTYAAY TCNCARACNTTYAAYGCNACNCCNACNCCNYTNCARCCNTCNTCNYTNGCNAAYAARYTN GGNGARGGNYTNTCNAARATHTCNATGAARGAYTCNTCN------YTNGAYAGYCAYCCN TCNTCNCARTAYGARCAYACNCCNTCNGCNGCNAGYGTNCCNACNAGYGTNAGYCAYCCN TCNGGNTCNACNTCNGCNTCNYTNTCNACNGGNACNAAYACNATHTCNTCNAAYTCNACN GTNTCNTCNGTNTCNTCNGCNTCNMGNGTNACNTCNATGCCNTCNACNTCNGGNAARGCN CCNCCNAAYYTNCCNCCNGGNGTNCCNYTNATGGGNCARTAYATHATGGGNCARAGYACN ATHCCNCCNTTYTAYAGYGTNCARCCNCCNATGTAYGGNTAYGARGAYATGCARYTNYTN CARCARMGNATGCCNGTNCARCCNGGNAAYTTYTAYGAYGTNAGYGCNTTYCCN---GCN GCNGCNGGNTCNAAYYTNCCNACNGGNMGNGAYCARCARCCNCCNATHCCNAGYGTNCCN TTYTCNGGNACNTCNGAYACNAARYTNAAYMGNGTNGAYGCNCARAGYCCNAAYGCNTCN AGYCARCCNCARAAYGCNCAYTCNGCNGCNCARCARCCNYTNTTYAAYTTYCAYTAYGGN TAYTAYTAYCCNTCNATGTTY---GGNGCNGCNGGNYTNCARTAYCCNACNACNGTNTAY CCNATHCCNCCNGTNACNAAYGCNGCNGCNCAYCCNGGNAGYACNTCNACNACNCARTTY CARAARTCNTTYCCNTCNCAYGTNYTNACNACNAARGGN--------------------- ---------------------------------------------------TCNGGNACN ---------------------AAYGAYAAYATHACNCCNAAYGCNTAYAGYAARTCNCAY GGNCAR---GGNYTNGAYAARCARGGNTAYCAYGGNGGNACNCCNCCNCCNTTYAAYTTY CCNYTN---TCNGCNACNCARACNGGNCCNATG---GCNCCNACNACNCCNTAYGCNGCN CCNTTYYTNCCNGTNATGGCNGCNCAYCARCCNCAYTCNCARATGATGCAYCAYCCNATG CARCARGAYTCNAAYAGYAGYAGYTCNMGNGGNYTNAAYCCNGCNGGNGGNCARGGNAAR TCNGGNACNGCNAARTCNTTYAGYGGNGCN---CCNTAYTGGAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNGGNYTNGAYTGYGCNAARGTNATHTCNATHYTNTGYGCNGCNTAYACNGCNAGYYTN ATHAGYTTYGTNAGYTCNGCNACNATHGCNYTNCAYYTNTCNGGNCCNATGGCNACNGTN AGYGTNGCNATHYTNTCNAGY---------------------------------CCNTTY MGNACNTGYTGYCCNCARATGTGGAAYTAYCARTGYMGNAGYAGYGTNATHCCNATGCCN TGYTTYGCNCARTGGTTYAGYGGNTCNTGGCARTGGTGYTGYCCNATHTGGCCNAAYATH GCNATHMGNMGN------TGYAAYTGYAGYAARTGYGCNGTNYTNAGYTCNGARTGYGCN AARGARGGNMGNTGYCAYMGNMGNTAYACNTGGMGNAGYTTYATGGCNGTNTGYTTYAAY AAYAAY---ATHTGGGGNACNATHMGNTTYATGAGYAARTAYGTNCCNACNAGYTGYGGN TGY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGTNTGYGTN CCNTGYTTYYTNATHCCNGTNATHYTNTGGATHTTYCAYAARTTYTTYAARCCNTGGYTN TCNAARTTYTGGAGYAAYTCNGARAAYTAYGTNACNAGYAAYYTNACNTGYCCNATGCCN AARAARAARAARGTNGARGGNGGNTCNGAYGGNAARGARGTNGARGGNACNAGYCARTCN AGYCCNGARGAYAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CAYCCNGAYGGNAARGARATGCARATHAAYYTNACNGGNTTYYTNAAY GGNAARAAYGCNMGNGTNTTYGTNGCNGARYTNTGGGAYCAYYTNTGYAGYGCNCARGAR AAYATHACNGGNATHCCNAAYGARTTYYTNGARCARAARAARAAYGARATHAARCARMGN CARGARGARCARGARMGNYTNCARGARCARYTNAARAARAAYGARCARCARATHAARGAR CARYTNTCNMGNGARMGNMGNGARYTNGARAAR--------------------------- ---AARGAYYTNAAYAAYYTNTCNCCNGAYMGNCCNAARCCNCCNGAYAGYAARCCNGTN YTNGAYTCNGGNGAYGTNCCNGARGTNAARGARGARGARAARCCNGARCCNAARCCNGAR ATHCARAGYGCNGGNGAYTCNAARCCNCCNCCNGAYGTN---AARACNGARTCNMGNGAR AARGAYAARGGN---------------AARGAYAARGARMGNACNCCNGARMGNMGNAAR GARCAYMGNGAYMGNGAYMGNMGNMGNCAYTCNMGNACNCCNGAYAARCAYMGN---CCN MGNTCNMGNTCNCCNGAYMGNCAYMGNMGNGAYMGNGAYMGNGAYMGNCCNGCNCAYGAY MGNGGNMGNTAYTCNCCN------------------------------------------ ---CCNMGNMGNMGNTCNMGNTCNCCNMGNMGNMGNTCNCCNCCN---MGNMGNMGNTCN CCNYTNCCNMGNTCNCCNTCNCCNGGN---------MGNAARMGNAAYGCNAARAARGCN GTNGAYACNMGNMGNGAY---------MGNTCNAGYTCNGARAGYAGYTCNAGYGGNTCN GAY------------GAYGGNTCNGCNAARGGNGAYTCNTCNCCNGAYAARGCNGGNATH CARCARMGNMGNAAYTAYMGNAARCAYGARGAR---AGYGGNAARGAYTCNTCNGAYGAY TCNGARGGN------GARAAYGGNMGNAARMGNCCNCCNCAYTCNMGNGAYMGNMGNAAY GCNMGNAGYCCNTCNCCNMGNMGNMGNMGNACNCCNCCNCCNAGYCCNMGNMGN------ ---CARAGYCCNCCNMGNMGNMGNTTYGCNTCNCCNCCNMGN------------------ ------MGNMGNATGAGYCCNATGCAYCAYMGNMGNAGYCCNTCNCCNMGNMGNMGNTCN CCNCCNMGNTTYTCNCCNCCNMGNMGNMGNAGYCCNCCNCCNCCNMGNMGNMGNATGTCN ATHTCNCCNMGNMGNMGNMGNTCNTCNGGNTCNCCNCCNMGNMGNCCNCCNTCNCCNTTY MGNGCNMGN---MGNMGNMGNACNTCNMGNTCNCCNTCNGAYTCNCCNGTNAARMGNMGN MGNTCNCCNCCNCCNGCNTCNCCNCCNCCNGTNMGNTCNMGNAARAARGCNTCNCCNCCN CCNTCNGAYTCNGARGAYAGYTCNAGYTCNGARGGNTCNGCN---TCNCCNGCNCCNCCN ------AARMGNAARGTNTTYAARGGNAARGARGARMGNYTNGTNCCNCCNCCNAARCAR CCNGCNTCNAGYAGYGARAGYTCNTCNTCNTCNGGNTCNGARGARAGYGAYGARGARTCN GAYTCNGAYGARAARTCNCARCCNAARCARTGGAARGAR---GCNTCNCCNTCNYTNAAR GCNAARCCNYTNCARMGNATGMGNACNCCNCCN---------------GAYGCNAAR--- ------------AARMGNMGNTCNMGNTCNMGNTCNCARTCNCCNGCNAAYMGNMGNGAY ---------------------CARMGNTCNGCNCCNCCNCCNMGNMGNAARMGNGGNAGY TCNMGNTCNCAYTCNMGNTCNCCNAAYMGNMGNGAYGCNMGNCAYAGYCCNCCNMGNACN GGNTCNMGNTCNCCNMGNMGNCARMGNAARGAYACNGAYTCNTCN---GAYCARGARYTN GCNMGN------------AARGCNMGNMGNMGNGARTCNCCNAGYCARGCNAARMGNMGN CCNGCNAARTCNCCNTCNCCN---------------MGNMGNGAYMGNGCNCCNMGNGAY GAYMGNMGNCARTCNCCNCCNMGNGAYAARGCNAARTCNGAYMGNCCNGAYAARAARCAR CAYGTNGCNGCNMGNAARGARAARMGNCCNCCNTCNTCNGAYAGYAGYAGYGGNAGYAGY TCNGARGARGARGARGARAARGAYTAYCCNGCN--------------------------- ------------------------------------------------------------ ------AARTCNAAYCCNAARGCNTCNGGNCCNMGNCCNTCNGCNCCN------GCNTCN AGYAARMGN---CARAGYGGNTCNCCNCCNCCNCCNAAYCCNCARGCNTCNAARTCNTCN AARMGNGAYAGYMGNGAY------ACNGAYGCNCCNMGNCCNTCNAARGTNAGY------ ---------MGNMGNTCNCCNAGYCCNGGNMGNGARTCNMGNAAYGGNAARGTNCCNTCN TCNTCN---------------------------------------------TCNTCNTCN GCNAARCCN---------AARAARGAYMGNCCNGTNCCNTCNGGNAGYGARGAYTCNGAR GGN---TCNGAYTCNGAY---AAYGCNAARAARAARAARAARAARAARGAYAARAARCAY AARAARCAYAARAARCAYAARAARCAYAARCAYAARAAR---------GARATHCARGAR AARGGNGARGAYYTNGARCARMGNYTNMGNGARAARGCNYTNAARTCNYTN------MGN AARAARCARTCNTCNGARCARGCNGAYAARGAYGAYTCNGAYAGYGGNAGYAGYAGYGAR GARGARGCN--------------------------------------------------- ---------------------------------------YTNGAYYTNACNGGNGCNGCN TAYCCNCARTAYGCNACNYTNAARTCNMGNYTNGAYACNTTYCARYTNTGGGAYCCNGGN CAYAGYAARCARCCNMGNGAYYTNGCNAAYYTNGGNTTYTTYTAYGCNGGNTAYTCNGAY TGYGCNMGNTGYTTYAAYTGYGGNYTNGGNYTNAARTAYTGGMGNCCNAAYGAYGAYGCN GCNTTYCARCAYGCNMGNTTYMGNCCNGGNTGYYTNTAYAAYMGNTTYATHAARGGNGTN GARTTYGTNGAYATGGTNCARCARAARATHCCNGARAGYGCNCARGCNMGNAAYAGYGGN ATHGAYGGNCCNAAYTGGAGYMGNYTNATGTCNACNGCNGCNGTNAARCARGCNYTNCAR GARGGNTGGCCNMGNACNCARGTNGTNAARGCNGTNGAYGAYYTNATHAAYGARYTNGGN GARGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ACN AARACNGCNGARGAYGTNGCNGARTTYAAYATHACNTCNYTNYTNCAYGARYTNGTNACN AAYGARAARTAYGARYTNCCNAARGTNGARGARAARGAYGGNAARGARGAR--------- ---ACNCARACNGCNACNYTNGARGARATHATHGARGARAAYACNGARAGYAARGARAAY GAY---------------------TCNAAYGARGAYAARGARGAYNNNGAYGGNTCNACN TCNCCNGAYAGYGARGAYTAYGARTGGYTNCARYTNGARGAYGTNAARGTNACNTTYYTN CCNYTNGCNTGYGTNGCNGARYTNTCNAARAARAGYAARTAYCARAARYTNTTYAAYGCN GTNTTYTTYGGNAAYAGYATGGTNCAYCAYYTNAARCCNGARATHACNGCNATGTTYGCN GAYAARTGYTCNGTNATHYTNGARACNGCNYTNTTYATGYTNCAYYTNAARAARAAYGAR GTNCARGARTTYATHAARMGNGTNGCNGGNATG--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAR--------------------------------------------- ---------------GARGAYAARGARCCNGARTAYAGYGARGARACNAARMGNYTNATH GCNGTNGCNGAYGARGCNMGNCAYAARTTYGAYGARACNGAYAARAARYTNMGNGAYCAY GARGAYGARATHAGYGAYATHAARAARTAYYTNGARATHGAYTTYGGNCCNAAYGARGAR TTYTCNAGYYTNAARGGNCARTGYTTYGARTAYACNGAYMGNGARTAYACNTAYMGNYTN TGYCCNTTYGAYAARAGYACNCARAARAAYAARAAYGGNGGNATHGARACNTCNYTNGGN ACNTGGGGNAARTGGCAYGGNCCNMGNGARGAYAARCAYAGYAGYATGATGTAYGARAAY GGNCARGGNTGYTGGAAYGGNCCNAGYMGNTCNACNCAYGTNAAYYTNCAYTGYGGNCCN ACNAAYGARGTNACNAGYGCNTCNGARCCNAGYMGNTGYGARTAYCARTTYGARTTYACN ACNCCNGCNMGNTGYGAYCCNCCNMGNGCNGCNGAR---TCNAGYGTNCAYGAYGARYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TCNTTYCAYGAYCCNATHGAYTTYACNGGNTAYACNGAR GCNTTYCAYGAYMGNCARATHGCNTGGGARMGNGCNCAYACNCARCCNCARTCNMGNGAY ATHGARGTNGGNTTYCCNGAYTTYAAYGTNACNATHMGNYTNGAYTTYCARGCNGARTAY TCNAAYGARYTNACNATHTTYACNTCNGTNATHGAYCCNGGNCARGCNMGNGCNTGYAAR GCNTTYATHAGYGARATHCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ACNGGNGGNYTNTTYGARGAYCCNCCNGTNATGCCNAAYGARTCN GCNGCNCCNGARTCNGCNCARGCNCCNTCNTCNCCNAARCARGAYGCNGTNTCNGARAAR MGNAAYGARGARGCNGARGARACNGTNCCNYTNCARGCNACNAAYGCNGGNATHTCNGCN GTNTCNAGYGTNACNGGNGARCARACNACNYTNGTNCAYAAYGARGARGARGCNTTYGCN YTNGARCCNYTNGAYATHACNACNGTNCCNGGNACNGARMGNAARGGNAARMGNAARMGN AARYTNATHGTNGAYGARCARAARGGNATHCCNAGYGARACNATGAARYTNCARYTNTCN GAYACNTCNGAYATHGTNACNTCNYTNGAYYTNGCNCCNCCNACNAARAARYTNATGYTN TGGAARGARACNGGNGGNGTNGARAARGTNTTYGTNYTNCCNGGNMGNCCNATHATHTCN AARTTYACNAGYAARYTNTTYTCNMGNCAYYTNGTNTGYAARTCNGTNTCNGAYGAYTAY GARCCNGGNTCNCAYMGNATHGAYYTNGAYATGGCNCCNGARGTNACNMGNGARAAYGAR MGNAAYAGYACNYTNCARGAYACNMGNYTNTCNGARATGTCNACNATHGTNGARGARCCN TCNGARACNTCNMGNMGNTCNTCNMGNCAYCARGARATHGCNGAYGCNTCNMGNMGNTCN GAYATGTCNATGGTNGARAAYCARTCNYTNTTYGAYCARATHCCNGAYAGYYTNCARCCN GTNGAYYTNCCNACNGAYCCNGCNAGYATGGTNGCNACNTTYAAYCCNYTNYTNGAYGAY GGNCCNCCNTCNGTNGCNCCNTTYTCNGTNCCNCCNCCNCCNGCNACNGTNACNGAYATG GARCCNGARCARGAYGCNGAYCARATGCCNGARACNGTNGARCARGARGARAARMGNTGG AGYAARMGNACNCARGTNATGCARGAYYTNTTYGARMGNGGNTTYGAYAAYCARGAYACN YTNAGYTTYAARGAYATGGCNMGNAAYYTNAAYMGNAARCARGCNGCNTCNMGNTTYTAY ACNYTNYTNGTNYTNAARAARCAYCARGCNGTNTGYACNGAYCARCCNGARGCNTAYGGN GAYATHTAYATHACNAGYGGNCCNCARTTYGGNATHGCNTGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CARACNGCNYTNACNATHAARYTNMGNAARGARGCNGARYTNGGNGAYATG GTNCARGARAARATHTCNGCNYTNCARMGNGARGTNGARAARYTNGARCARGARYTNAAR CARGCNCARGTNAAYAAYYTNAARAARYTNCARAGYGCNGCNGGNAAYGAYGTNGAYTCN ATHTGYATHYTNCCNMGNTAYTTYAARCARTTYYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GTNGAYGGN AAYAARYTNATGTCNTTYGGNGGNTCNCAYGGNGGNTTYYTNACNACNCAYYTNATHGGN CARTAYCCNAARACNTTYAARGCNGCNTGYTCNMGNAAYCCNGTNACNAAYYTNGGNTCN ATGTAYTCNGTNACNGAYATHMGNGAYTGGATHTTYGTNGARGGNGGNTTYCCNTTYTCN ATGTCNTCNYTNGTNGAYGARACNGTNTAYCCNGGNYTNTGGAARAAYTCNCCNYTNTCN TAYGTNGAYCARGTNAGYACNCCNTAYTAYAARMGNCARGTNCCNACNMGNTGYYTNACN TAYCCNTCNAGYAAYCAYAGYYTNGCNGARGTNGAYGTNGARGGNGAYTGYYTNGTNAAY ACNGTNGTNTGGTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CAYAAY ATHGAYGARYTNTTYGAYMGNGARGARYTNTCNGCNGCNCCNGAYGCNGGNTGGCCNGAY TGYTTYAAYTCNGGNGTNTTYGTNTTYMGNCCNTCNGAYACNACNTAYTCNAAYYTNYTN GCNYTNGCNATGTCNCAYGGNTCNTTYGAYGGNGGNGAYCARGGNYTNYTNAAYYTNTAY TTYAAYACNTGGGCNACNGCNGAYATHAGYAARCAYYTNCCNTTYACNTAYAAYGTNGTN TCNCARGCNTTYTAYAGYTAYYTNCCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNCARCCNATHTGYGARYTN AAYATGTTYYTNGARGAYACNAARMGNCCNMGNGAYATHGAYATHCCNYTNCCNACNGAR TCNAGYYTNYTNACNTCNTTYAAYGARACNGCNGTNGARCCNGARTCNAAYGARGGNYTN GCNACNCCNCCNTTYTCNGGNGGNAGYACNCCNCARTCNCARTCNMGNGCNGCNTCNCCN ACNTGGAGYGARAGYAGYGGNAAYYTNAGYGCNAGYAGYTCNTCNTGYTCNCARAARTCN YTNGGN---------------AGYGCNCCNATHCCNMGNCAYAARMGNCCNTCNCAYMGN MGNGCNGARGTNAARMGNMGNGAYAARATHAARACNTGYYTNGAYGAYATHAARGTNCAR GTNCCNTCNYTNCAYGARAARGGNAARYTNAGYGARTCNACNGTNYTNTTYAARGCNGCN GARTAYATHCAYCAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARGCNGAYYTNGTNCAYMGNMGNYTNATHTGYACNAARAAYCCNGGNCAYGAYCAR TTYATHCCNATHAARGARTTYTCNATHGCNGAYYTNCCNGARTCNYTNAARYTNGARCAR ATHATGGAYTAYYTNAARGCNYTNAGYAARYTNATHGTNMGNATHCARGTNAARTCNACN AGYGAYTGYMGNCAYAARGARGAYCCNTTYTCNACNATGATHGGNMGNACNGTNTAYMGN GGNGCNACNGGNAGYGTNAGYGGNGTNAGYGARGTNAARGAYATHCARGARATHCCNTGY AARGAYGARTCNTGYATHCARGGN------ATHGARCAYAGYCARTAYGGNTTYATHGAR ATHMGNACNAAYMGNCAYGCNGTNGCNGAYACNATGGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GARGARGTNCCNGTNTTYGTNCAYYTNYTNTTYGCNMGNGAYACNTCN GCNACNGTNGCNGAYTTYATHCARAAYCAYYTNAAYMGNGTNGGNGAYACNGGNGGNYTN GARCARGTNGARATGTGYYTNYTNGCNCAYACNYTNGGNATHAGYATHMGNGTNYTNMGN YTNTCNCAYAGYGAYCARGARGAYTTYGAYTGYTGYTTYCCNGAYGAYATGCCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARYTNATGGTNTAYGTN AARAARAAYGGNTCNATGTTYATHAARGAYATHGGNACNGGNTCNGCNYTNTGYCARATH TCNYTNCCNGCNACNCAYTCNATHCARACNCCNTGGAAYCCNATHTTYGCNYTNGGNTCN GGNGGNCARGTNYTNTAYYTNAARGGNGARGGNTCNGAYGTNAGYGARGAYGGNGARGTN AGYAAYATHTCNTGYYTNTTYAARTTYAAYYTNMGNAARTAYTCNGCNYTNGARGARTAY TGGYTNMGNCCNCAYGTNAARACNGAYYTNGTNGTNTAYACNACNCAYCARCARMGNYTN GAYGCNYTNATGAARGARMGNYTNCARCARCARGCNATGMGNAARCCNMGNATGCARAAR CAYTGGGGNCARYTNMGNGGNGARYTNGAYATHATHCARAAYACNMGNAAYATHCCNGTN GAYACNYTNMGNYTNTCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNCCNGCNTAYGCNACNCCNCCNGCNTCNYTN CAYMGNGTNGGNYTNGARTCNAGYTCNACNGGNTCNTCNTTYCCNGCNGAYTTYACNAAR CCNGTNCCNYTNGCNGTNGTNTCNCCNGAYAGYMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNACNGAYGCNCARYTNGCNGCNAARYTNGTNGTNGARGARAARGGNTAYGAYGTNAAY GAYGARGTNATHGCNMGNATGYTNCARAARGARTTYGAYAARGARTTYGAYTCNGCNYTN TCNAARMGNGARCARTTYTTYAAYGGNAAYAGYAARGTNTCNATHTCNTAYGAYAAYTTY AARMGNAARCAYYTNCARGGNGARTAYCARGGNGGNGARATHGAYGAYGAYGAYGAYYTN GAYGGNGTNGAYACNCCNGARTAYTCNGARAARATGCCNTGGGARAARGGNACNCCNGTN ATHGGNGCNMGNGGNTAYAGYGGNCARGGNAARAAYATHGTNACNAARCAYGAYAGYGTN ATHTGYGGNMGNMGNAAYGCNCARAARYTNATGCARTTYCCNCCNGARTTYGAYTGYGGN GAYGGNGARGGNATGGAYATGCARYTNCCNAAYAARGTNTAYAAYAARYTNAARMGNCAY TCNCARGCNGARAAYAARAARGGNCARAARGTNCAYGAYAARAARGAYCAYTCNACNGCN ATHAARGCNGTNGAYGARAARACNMGNATHYTNATHTTYAARATGATHAAYTCNGARTTY YTNACNTCNGTNGAYGGNGTNGTNAGYGARGGNAARGARGCNGTNGTNTTYAARGCNATH GGNGGNMGNAARGAYGAYGTNGARYTNCCNAARGAYGTNATHYTNAARATHTAYAARACN TCNATGAAYGARTTYAARACNMGNYTNAARTAYATHCAYGGNGAYTAYMGNYTNTCNAAR GAYGTNTTYMGNAARTTYAAYGCNMGNAARYTNATGGCNATHTGGGCNGARAARGARTAY YTNAAYYTNAARAARATGCARMGNCAYGGNGTNCCNTGYCCNGAYCCNYTNACNYTNAAR AARCAYGTNYTNGCNATGTCNTGYATHGGNGGNGAYAARCCNGCNCCNAARYTNMGNGAY ATHATHTTYCAYGCNGAYGARATHCARGAYGCNTAYGARCARACNGTNAAYYTNATHAAR ACNATHTAYCAYAARTGYAAYATGGTNCAYGCNGAYTTYAGYCCNTAYAAYYTNYTNTGG TAYGAYAARAARGTNTGGGTNATHGAYGTNGGNCARGCNGTNGAYMGNGAYAAYAARAAY TCNACNGCNTTYYTNATHMGNGAYTGYAARAAYACNTGYGAYTTYTTYAARCARGCNGGN GCNCAYAAYGTNCCNAAYGCNGARGGNYTNTAYAAYGARATHACNGGNYTNTCNYTNGAR GGNGAYGGNYTNATHTTYGARTCNCAYGGNTGYMGNTAYGARAARGARAARTAYGCNTTY GAYTAYTTYTTYGARYTNGCNGARTCNGCNMGNTCNGARAAYAARAGYGARGAYAAYAGY ACNGAYAGYGAYAGYGAYGARGARYTNGARGARGAYGARGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TAYAGYTAYCARTCNYTNGTNTGGAAYAARATGGCNTCNAARMGN YTNGCNCARYTNGGNMGNAGYGTNYTNCCNGGNGAYYTNGTNATG--------------- ---------GAYAARYTNGCNGAYACNTCNAGYCCNACNYTNGTNACNGARGARACNGTN GGNAAYTAYTCNYTNAGYGAYGTNGTNYTNCCNYTNCCNGGNTAYGAYGTNATHTAYCCN AAYAAYCARGTNGGNGARTGGTAYAARGARTGYYTNGARGGNGAYGGNYTNGAYATHGGN AAYATGAARMGNCCNCARAARGAYTAYTCNYTNCCNGGNGCNTAYMGNCCNYTNGTNATH GTNCCNAARGARGTNTGYTGGACNCAYCAYCAYTAYGAYGAYTAYACNCARGCNYTNACN YTNAGYGAYTTYGAYYTNATHAARGGNGARACNATH---CAR---GAYGGNCARACNGGN AGYYTNMGNGCNGTNGTNYTNMGNYTNTCNYTNCCNTCNTCNTGYTAYGCNACNATGGCN YTNMGNGARGTNATGMGNGTNGAYACNTCNTCNTTYCAYCARTCNACNYTNAAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AAYMGNYTNAARMGNAAR CCNAAYYTNTCNTCNTCNGAYGARYTNTGYGARGTNATHACNGAYACNYTNGGNTCNTAY YTNGARAAYGCNGAYAARACNGARYTNCARTAYGTNAAYGARGTNTAYAARGTNAARACN GARAAYGTNGARCCNATHGAYAARAAYGARACNGGNGAYGTNAARGTNACNGTNAARATH TTYGTNTGYGARTCNCARTCNCCNAGYGTNGTNGARGAYGCNGTNGAYAARGTNYTNAAY GARYTNGGNACNACNTTYATHGARACNYTNYTNYTNGCNGTNGGNACNGAYMGNGARGAR GARCARGARCCNGARGAYACNGTNAAYYTNGCNTCNATHCARMGNTTYTGGYTNACNATG CARGARATGGTNGCNAARGAYAARGTNATHTCNYTNGGNGTNTGYGAYYTNGGNAARGAR GGNYTNGARTCNYTNTAYACNTGGGCNCARGTNAARCCNGCNATHAAYCARGTNAAYYTN GARTCNTGYTGYGTNYTNCCNAARGAYYTNACNGARTAYGCNAARGGNATHAAYATHCAR YTNYTNACNCAYAAYGAYAGYCCNGAYTTYYTNACNAARGARYTNYTNCARGARAARATH CARTCNGTNGCNACNGARMGNGAYAGYGAYGCNTGGAGYCCNCARTGGGTNGTNMGNTAY TCNGGNATHYTNAARAAYMGNGGNATHATHAARATGAARGGNTAYATHTTYCAYGCNACN MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARATHATHATHMGNGGNAARGGNTCN GTNAARGAYGGNAARATHGGNMGNAARGAYGGNCARCCNYTNCCNGGNGARGAYGARCCN YTNCAYGCNTAYGTNACNGCNAAYAAYCCNGARAAYGTNMGNAARGCNGTNGARAARATH AARGAYATHATHAARCARGGNATHGARGTNCCNGARGGNCARAAYGAYYTNMGNMGNCAR CARYTNMGNGARYTNGCNYTNYTNAAYGGNACNYTNMGNGARAAYGAYGGNYTNTCNAAR YTNMGNCARATHGCNGARAGYCARACNATHGTNACNAAYACNATHATHTGYACNGTNTGY GGNGGNACNGGNCAYATHGCNCARGAYTGYAARCARAARMGNCCNGGNGAYTCNTTYMGN ATGCARCARATGCARAAYCCNGCNGAYMGNGCNAARATGGAYAGYGARTAYATGTCNYTN ATGGCNGARYTNGGNGARGGNCCNCCNCCNCCNAARACNGARTCNTCNAAYATGGGNCAY ---------------AAYCARCCNCCNTTYAAYMGNCCNYTNYTNACNAAYCCNCCNCCN AAYCCNATGGCNYTNAAYTCNCCNTGGCARATGCCNCCN---AAYMGNCCNCCNATGTCN AAYCCNGTNCCNCCNCCNCCNTCNAGYTCNGGNCCNCCNYTNYTNAAYMGNCCNCCNATG GGNATGCARACNACNGCNCCNCARATHAAYCCNATGGGNMGNYTNCCNATGCCNYTNATG TCNACNCCNGTNCARCCNCCNCCNGGNATGCARGGNTCNCCNGCNYTNYTNCCNCCNCCN ATGGGNGGNATGCARCARAAYCARCARATGGGNGGNATGCARCARAAYCARCARATGGGN GGNATGCARCARCARCCNCCNCAYCAYCARCARCARCARCARCAYCARCCNCCNCAYACN CARCAR------CARCARCCNYTNMGNCCNTGGCARCARCCNGCNAAYCARTCNCARCCN YTNATGAAYCARGGNGTNGCNTCNAGYGCNGGN---ATGGGNATGCCNCCNCCNCCNGCN TCNYTNATGAGYCCNCCNCCNCCNCCNCCNGTNAGY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNYTNMGNGAYYTNTAYMGNGGNTCNMGNCARGTNCCN GARMGNCAYGAYYTNACNGTNTTYCCNACNGTNAAYGAYYTNAARAAYCAYATHCAYCAR GCNYTNACNGAYATHCARAAYGGNTCNYTNACNAGYTTYGCNCCNYTNACNCCNCCNATG GAYATGCARGGNAARGARGARTGYGARAARGARGAY---AARAGYCAYGARGARMGNTCN GARYTNCCNACNYTNTGGACNGGNTCNGCNATGCCNGARACNGTNACNGTNACNYTNACN CARAAYCCNGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARGAYGTNTCNYTNCAYAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARTTYYTNATG GARCARAGYGARCAYTTYGAYATHTCNTCNYTNYTNAAYTGYYTNCAYMGNYTNAARGCN GARAAYAARCARYTNGARGAYGARGTNTCNGAYYTNTCNTCNMGNMGNAAYCAYYTNATG ACNGTNAAYGCNMGNYTNTCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAY ACNYTNTAYTAYGAYTCNTGGTGGATGTGGCARCAYGTNTCNYTNACNTGGYTNAGYGCN YTNYTNATGYTNACNGCNCAYTTYYTNCCNCCNCAYTAYYTNCAYYTNYTNCAYAARAGY GCNMGNCAYYTNGCNMGNTGGCARMGNATGGARGCNMGNCAYGCNCAYGTNCCNTAYAAY GCNTGGTCNGARYTNCARGTNTGGCCNCARGGNGCNYTNGTNAARCAYGTNMGNGGNYTN TTYAARGCNGARGGNATHAAYGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYGAYTGGTTYCAYGGNAGYATHAGYMGNGARGARGGNGAR MGNMGNYTNAAYAGYATHGGNAARCCNGGNACNTTYYTNATHMGNACNAGYACNAARAAY AAY---------TAYCCNTAYACNYTNGTNATHMGNACNGCNTTYGAYYTNAARACNATG MGNATHMGNGARMGNCCNGAYGGNAGYTTYGTNYTNGGNATHACNGTNMGNTCNGAYGAR ATHAGYTTYCCNACNYTNGARGARYTNGTNGARTAYCAYAARAGYCAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ACNAAYTCNTGYACNGTNGAYAGYCAYYTNACNAARACNTCNACNACNAARGCN TTYGTNTTYGAYACNCCNACNAAYTAYTCNATHCCNGTNTTYCARCCNATGAAYATHCAR GARGCNCCNMGNATGTAYTAYMGNCCNTGGMGNGGNGAYAARYTNCCNGTNGGNGAYGTN CCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TTYGARGGNYTNGTNGGNAARGAYMGNTCNMGNGTNTGGGAYCAYATGCAR TTYTGGGARGAYATGTTYYTNGAYGCNGTNGCNCARGARMGNGAYATHATHGGNATGGAY CARMGNCCNTCNGARATGATGGARMGNTAYGARTCNYTNGGNGARTTYGARMGNAARMGN YTNGARTAYGAYGARGAYTGYGTNYTNTCNATGATGYTNTTYAAYYTNTCNGCNTTYATG YTNATGATGMGNGTNCCNAARCARGARATHAARAARAARGTNMGNMGNYTNATGGGNAAR TCNCAYATHGGNYTNGCNCAYAGYCARGARATHAAYAAYYTNYTNGAYAAYATHCARAAY YTNCARMGNCARAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MGNYTNGGNGAY GCNGTNYTNMGNGCNMGNYTNGARAARMGNTCNGTNACNGAYGTNATHGTNGARCARGAR AAYGGNGARCAYGTNATHACNGGNAARGTNGTNGAYATHMGNCARGARACNAGYGGNGGN TTYAAYAARGGNCAYGTNTTYATHGARGGNATHGAYGAYTTYYTNGGNCARGCNGTNGTN ATHGARTTYCARAAYGARTTYYTNGTNGTNTTYCCNYTNGTNGCNGGNGARMGNGGNCCN GCNMGNTGYTGYGTNCCNGAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GTNACNGGNTTYGGN YTNGTNTGYTTYGCNGTNTGGAARATGATGGGNGTNCAYAGYATGGTNGARTTYMGNGAR AARATHGGNAAYGCNYTNCCNMGNYTNAARMGNCCNGARAGYACNGGNMGNAAYGARTTY GCNACNATHMGNGAYYTNTTYAAYTAYATHATHGAYGARGAYAARAARGCNAARGCNYTN AARGTNGARAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TCNAGYATHGTNTGYCAY CARTGY---------CARTAYGAYTCNTGYGGNGAYGAYTAY------------AGYAAY GAYCCNGCNAAYYTNGGNGARTGYGAYGAYGAYCARTAYTGYGTNAARTAYAARACNACN GTNTGGATHMGNAAYTCNGGNGARATHACNGGNAARYTNACNAAYTCNTCNGTNGTNACN MGNACNTGYGARTCNAARAARGGNAARAGYGARGGNTGYACNGGNTGGCARAAYAAYGGN GGNGTNACNYTNAARTGYTGGTGYGGNTCNAAYAAYTGYAAYAGYGGNCAYTCNYTNMGN CCNGTNGGNACNCCNGTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CARTCNGCNAARGAYATHYTNGAYTCNATHCARGGN MGNCCNAARAARAGYAARTCNGCNGGNAARAARGTNATHCCNCCNYTNATGYTNGAYTCN YTNGGNMGNCCNATGATHCCNATGATGYTNGGNGAYATHACNYTNCAYAGYATGGGNGAR ATHGTNACNGAYMGNYTNAGYTTYCAYAGYCCNGTNGCNATHTTYCCNGCNGGNTAYTGY ATHACNMGNGTNTAYATHAGYYTNCAYAARCCNGAYGCNAARTGYYTNTAYACNTGYAAR ATHTCNGARGGNGAYAAYGAYCCNYTNTTYGARATHGCNCCNGARGAYAGYTCNGAYATH GTNTTYMGNGCNAAYACNCCNGCNGARTGYCAYAAYYTNYTNYTNMGNGCNGTNAAYAAR TCNMGNGGNGCNGAYGTNYTNATGACNGARACNACNGGNYTNGAYTTYTTYGGNYTNTCN CAYTCNGTNATHCARAAYYTNATHCARTCNATHCCNGGNGCNMGNAARTGYTCNMGNTAY AARTGGGTNAARTTYGARATHGAYAARACNGARTCNAAYGARAAYTTYTGYGTNGGNAAY AAYGAYCCNACNATHAGYTAYGARGCNTTYATGAARCAYGTNTCNACNGTNGGNCARYTN MGNCCNGGNCAY---GCNTCNCARATGGARAARTCNACNAGYYTNMGNTCNYTNYTNACN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHGCNATGAARYTNAARAARGCNGARCARMGNMGNAGYYTN ATHGARCARGARAARYTNGAYCARYTNGCNAARGARMGNCARAARTAYATHGARGTNYTN ACNAARGCNCARTCNGARAGYCARGARTTYATHAARAARACNGARGARAARYTNAARMGN TCNATGGARAAYMGNMGNGARAARMGNGARACNCARATHMGNGCNYTNCARGARMGNYTN MGNGARCAYTCNGTNAARGTNCAYGARGTNCARAARACNGGNATGGARATGGTNAARGAR TTYGARGCNAARGCNGARCARAARYTNAAYCARAARATGTCNGCNTAYGARGARAAYMGN AARAAYCARYTNTGYAAYACNYTNGCNAARYTNCARGARCAYGCNAAYCAYATHAAYGAR GTNTGYYTNGCNAGYGARACNMGNGGNCCNAAYACNGAYGARYTNCARGARCARYTNGTN CARAARATGGARAAYGCNYTNAARAAYMGNGARGARCARYTNMGNTCNATHCARGAYMGN YTNGCNGARCAYGARAAYMGNATHAARGARGTNCARMGNAARAARGGNATGGTNTCNTCN GGNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNGGNTCNTCNAARGGNCCN GCNGTNACNGTNGCNGTNTCNTAYCCNAARMGNGTNTCNTCNAGYGCNAGYGTNACNAGY GTNGCNTCNTCNGTNTCNTCNCCNAGYAARGTNCAYAGYAGYCCNAARAAYGGNAARGCN CARTCNGARTCNCARGCN---TCNACNGGNAARGCN---CARACNGARCARACNAARCCN GCNAARAGYAARAARAAYAARAARAARAAYAARAAYGGNGAYGTNCAYGAYCCNGARGGN GTNTTYATGCCNAARTCNGARTCNGARYTNAAYGGNGCNGTNGAYGAYTTYGARMGNGAR YTNGARGARTTYAARMGNTTYTGYTAYGARACNTCNGARCCNAARGARAARMGNAARYTN GCNGTNAAYGTNAAYYTNAARGAYATHTTYAARAARAARTCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN GGNATH---TGGGTNGARCARGAYGTNYTNMGNAARMGNATGGARCAYAARTGGMGNTCN TAYTTYGARAAYGTNCCNMGNAGYGCNAARMGNCCNGCNCCNCARAARCCNAARCCNAAR CCNCARCARAARCCNAARGCNAARCCNAAYCCNGTN---CCNGAYGAYGAYGAYGCNAAY AAYATHGTNTTYGTNACNCCNCCNYTNACNCCNCCNCCNCCNGARAARGARYTNGTNGAR YTNCCNAARGCNTTYGARAARGAYAAYGARTTYTGGAGYTTYTAYGAYCAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYAAYTGYAAYTCNTGYGAYTTYGTNGCN AAYTGYCAYTAYAARGGNAARAARCCNCCNTTYGCNAARAAYTTYYTNYTNCAYGARGAY TGYTTYGTNATGAARGAYCCNTTYTCNACNTCNGGNGGNTTYATHAGYGTNGGNGCNATG TGYTCNYTNTGYAARGARCCNGTNTGYATGTCNACNCARTGYAGYTTYTTYTAYACNCAR MGNATHTGYYTNAARTGYGGNTTYGAYCAYYTNAAYGARTTYCCNTCNGARYTNCAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GAYAARTTYGGNGTNGTNCARGGNTCNYTNCCNYTNATHTTYYTNACNYTNYTNGARYTN CAYGARTCNYTNGARAARCAYTTYAARYTNACNTCNTCNCCNMGNMGNACNAAYGGNTCN YTNCARTCNTCNGAYGAYTGYATHATHMGNTTYAARYTNCARTCNATGYTNAARGCNTCN YTNTAYMGNGTNGTNAAYACNTAYAARCCNCAYYTNMGNGAYATGAARYTNAGYCCNGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GCNAAY GTNTTYATHAGYATHAARGGNGAYGARGAYGTNYTNYTNCCNACNCARYTNACNMGNGGN CARTCNAARAARMGNATHTTYTTYGCNCCNGGNTCNAARGARACNTTYTTYATHAARGGN CCNCARYTNGGNAAYYTNGARATHYTNTCNATHGARCAYGAYGGNATGGARAARAARCAY GGNTGGTAYTGYGAYAARGTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGCCNTAYYTNAARATHGAYACNAAYYTNCCNAARAAYAARATHCCN GAYGAYTTYYTNCARGARGCNACNGARYTNATHTCNTCNGARYTNGGNAARCCNGCNTCN TAYGTNTGYATHCARGTNTGYCCNGAYCARGTNATGAGYTTYGGNGGNAARGAYGAYYTN TGYGCNAAYATHACNYTNAAYTGYATHGGNGTNGTNGGNCCNGARAARAAYMGNCAYYTN GCNCCNGTNYTNTCNAAYTTYATHGARMGNAARYTNGGNATHAARCARGAYMGNTTYTAY ATHAAYATHTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AAYTAYCCNACNCARAARGARTGGGAYGGNMGNYTNAARATGGARYTNTCN MGNGCNATHAARTGYCCNTCNATHCARTAYCARYTNGCNGGNGCNAARAARATHCARCAR GARYTNGCNMGNCCNGGNGTNYTNGARMGNTAYATHGAYGAYCAYAARGTNGTNGAYCAR ATHMGNACNACNTTYGCNGGNYTNTAYAGYYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARTCNMGN GGNACNTTYGAYTTYYTNAARTCNTTYATGGCNMGNATGYTNTCNATHATHACNTTYACN ATH---------ATHGCNATHGTNATHCCNATHTCNATGATHGTNGTNGGNTCNGTNCAY YTNGAYGAYTGYGAYGCNGARMGNATGATHCCNATHTAYATGGTNGTNGCNGGNTGYGTN GCNTTYGTNCARAAYYTNATHMGNYTNGTNCCNCAYTGYTAYCAYACNGARGARGGNMGN CARGARTCNCARAARAARGTNGAYATHGCNAAYTAYATHATHAAYMGNTTYATHYTNYTN TGGYTNATHATHGGNTGYGCNTAYGTNTAYGGNACN---AARGAYTCNTTYCARTCNAGY GAYAARAAYGCNTCNGAYTAYTGYGAYTAYACNYTNTAYTGGTAYGCNTTYTGGGTNACN ACNGCNGTNTAYATHTTYATGGCNGTNTCNTGYYTNTGYGCNTGYATHGARGGN---YTN GTNGCNTGYTTYAGYAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AAYCCNGARYTNAARGARATGGARAARGTNTAYCARGAR YTNAARCARAARGGNATHGARTTYCCNATGACNGAYYTNGAYAAYATGGCNCCNATHCAY ACNCCNGCNMGNAGYGTNCCNGAYMGNGARCARCARCARCARGTNAAYGAYMGNGGNGGN AGYAGYMGNGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGGTNGGNMGNGAYTTYYTNAGYYTNAARCAYTTYAARCCNGARGAR ATHAARCARYTNYTNTGGACNGCNAARGAYYTNAARACNMGNATHAARGARAAYGARGAR GTNTTYCARCCNYTNGCNGGNAARACNGCNGCNYTNATHTTYCARAARMGNAGYACNMGN ACNMGNYTNTCNTCNGARYTNGGNTTYGCNMGNYTNGGNGGNCAYGCNTCNTTYYTNGGN CCNGARGAYATHCAYYTNGGNGTNAGYGARAGYGTNGARGAYACNTCNAARGTNYTNGCN GGNATGGCNGAYGTNATHYTNGCNMGNGTNTAYGARCARGARTTYYTNGAYACNYTNGCN AAYAARTCNTCNGTNCCNGTNATHAGYGGNYTNTCNGAYYTNYTNCAYCCNYTNCARATH YTNGCNGAYTTYYTNACNYTNCARGARCAYTTYGGNTAYYTNCAYGGNTGYAARATHGCN TGGGTNGGNGAYGGNAAYAAYATHYTNCAYTCNYTNATGTAYGGNTGYGCNAARYTNGGN ATHGAYYTNAGYGTNGCNACNCCNGTNGGNTAYGARCCNGAYGCNGAYATHACNAAYGAR GCNATGAARATHGCNMGNAARACNGGNGCNTCNTTYCARATGGGNAAYAARCCNGTNGAY GCNGTNTAYMGNGCNGAYGCNATHGTNACNGAYACNTGGGTNAGYATGGGNCARGARGAR GARAAR---MGNAARMGNYTNGTNGAYTTYGAYGGNTAYCARGTNAAYMGNGARATGYTN AARGARGCNGGNGGNAAYTGGGTNTTYYTNCAYTGYYTNCCNMGNAARCARGARGARGTN ACNGAYGAYGTNTTYTAYGGNGARGARTCNYTNGTNTGGCARGARGCNGARAAYMGNATG TGGACNGTNATGTCNGTNATGYTNCAYYTNYTNCARCCNTAYACNCCNACNATHCCNATG CCNAARTTYGTNMGNGGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CARACNGGNATGMGNYTNATGGTNAARTGYMGNATGYTNYTNCARGAR AAYGGNGARYTNGGNAARATGATHTCNTCNGGNMGNACNGCNAARYTNGARGGNGARATH TCNYTNCAYAARGCNYTNGTNGCNGARATGAARAARAAYCARAARGARYTNGAYGARTTY GTNGGNGARYTNGARGARGAYGTNGARGGNATGCARGGNATGATHTTYATGYTNCARCAR CARYTNAARGARGCNMGNGARCARATHTCNMGNYTNCARCARGARAAYGARCARYTNMGN ACNYTNCARYTNCCNTCNGAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARGARACNGGNACNTGGGTNCARTGYTCNATHTCNGARTGYGGNAARTGGMGNTAYGTN GAYGAYATHTCNGAYCCNGTNAARGTNCCNGAYYTNTGGGARTGYAAYATGAAYTCNGAY AARGAYCAYAAYTCNTGYGAYGCNCCNGARGTNGARTAYGAYGARAGYGARCAYATHYTN ACNAARTAYACNYTNGGNTCNGTNGTNTGGGCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TCNGCNACNTCNTGGGARGTNGTNGGNAARGGNAARAARGGNAARGGNGAYTCNAAR AAYYTNTCNCCNGCNAARGARAARGARYTNYTNGAYAAYATGCCNMGNATHTCNAARAAY GGNCCNGTNCARYTNGAYGAYACNYTNTAYTCNATHTTYYTNCCNAARGARAGYAARCCN ACNAAYACNACNAAYGCNAARGARGAYGCNAAYAGYAARCARAAYGGNAAYAARAARTCN AAYAAYCARAARAARAARAARCARGAYGARCARAARAARAARCCNAARCCNGTNAAYYTN GARACNGCNYTNGCNTCNYTNGAYCCNAARGAYYTNCARAGYGTNATHAGYAARTCNCAR YTNTTYTTYCCNAAYCAYCCNGTNGTNTGGYTNAARGAYGTNGCNTCNTAYYTNAAYATH CARYTNGARAAYACNATHGARACNGAYCCNGCNTAYAARGAYAARTCNATHGGNTTYCCN YTNAAYGCNGTNCCNACNGGNTAYGCNAAYGTNYTNCAYTCNTTYATGAARCARTTYTCN AARCARACNYTNGAYGAYATHCAYTAYTAYGGNATHCARACNATGYTNCARGARGCNGCN AARGGNATHCCNATHCAYGGNTAYAARATHTTYYTNCARYTNYTNGCNCARACNAARCCN GAYGTNATHATGGAYAARATGTCNCARTAYYTNGAYYTNYTNAARATGCAYCARAAYAAY CCNTCNAARTGYYTNTCNATGYTNTGGGCNYTNGGNCARTGYGGNYTNAARAAYTTYAAY TGYGGNYTNAARGTNTGGYTNAAYYTNATGYTNCCNGCNYTNGARGTNMGNCARGTNGCN CAYTAYCCNGTNGARTAYYTNGARGCNYTNGTNAARTCNAAYAARAARTCNACNAARAAR ------------AGYTAYGGNYTNGTNAGYYTNMGNGAYTAYTTYCAYGTNATGGAYGTN TTYTTYAGYCCNAARTTYACNYTNGCNAAYGAYYTNAARAARMGNYTNATHGTNYTNTAY CCNTTYATHAARACNYTNGCNTAYGGNGARGARCCNGCNCARAAYYTNMGNACNTTYTTY CCNTCNTAYYTNACNMGNTAYGCNTCNACNAAYTCNCARCCNATGAARGAYGARYTNYTN GARTGYATGACNCAYTGYYTNATHACNGAYAARCARTCNTTYAGYGTNTGGTGYCARYTN TAYACNAARCAYYTNCCNGCNTCNAGYCAYYTNYTNGARCAYATHAAYMGNAARTGGCCN AARYTNTCNTCNAARTTYGAYAARAARATHYTNAARGARACNYTNMGNTCNTTYTCNGTN ACNAAYGARGARYTNGARGTNCARAGYAARGGNAARYTNGAYGGNYTNAARCARTGYAAR GCNGCNACNAARACNYTNYTNACNMGNYTNACNGGNACNACNTTYCCNTGGAGYYTNYTN GTNTTYGTNATHGTNTCNGTNYTNGCNGCNATHGTNATHTAYGAYATHATGTCNAGYCCN AGYTTYMGNTCNTCNAARATHATGCARTTYYTNGARCAYTAYGGNATHYTNGCNYTNYTN GAYAAYTTYTAYCARTGYGTNYTNAAYGTNATHACNYTNTCNATHAAYTGGYTNAARAAR AAYTTYCCNGTNTAYTAYGCNTAYGTNTGYGAYACNGTNGGNCCNGCNYTNATHGTNGCN TGGCARACNACNMGNGAYTTYATGATHAAYGCNGARGCNGCNTCNMGNCCNTAYMGNGCN YTNATGYTNGARAARGTNATHCARTTYTAYCAYTGGGTNTAYGAYYTNTCNCCNGARTTY TGGATHMGNTGYGGNGARATGTCNTGGYTNGCNTGGGAYATHYTNAARGAYTAYTCNYTN TGYYTNTGGAARCAYACNGTNCARTTYGCNGGNGARGCNGAYCAYTGGYTNACNGARCAY GTNYTNACNGGNTCNTTYTCNAARGARATGATHAARGAYACNGCNYTNMGNGGNGTNGAR CAYYTNCARAAYTGYACNTCNTTYYTNATGACNTGG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARAGYATHAGYYTNYTN CARGAYGARYTNGAYCAYYTNTCNAARGARAARTCNYTNYTNAAYAARATHCCNGAYACN GAYATHATGGCNAGY---AARGTNAARCARYTNGARGARGARGAYATGATGTTYMGNAAR CAYYTNGGNATGGARATH------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARCARGGNGARGCNACNATGAARGARYTNCARAAYTCNGGNGGNCARGAYMGNGTN GCNTTYTTYCARGGNAAYGTNACNGAYCARGARGGNTTYAARGCNGTNTTYCARAARACN AARGAYCARYTNGGNGGNYTNGAYATHGTNGTNAAYAAYGCNGGNGTNGGNGGNGARTCN GGNTGGGARMGNACNATHGAYATHAAYGTNAAYGGNACNATHMGNGGNACNYTNYTNGCN ATHGARCAYYTNMGNAARGAYATHGGNGGNMGNGGNGGNGTNATHGTNAAYGTNGCNAGY YTNGCNGGNYTNAARCCNAAYCCNTGYTCNCCNGCNTAYTGYGCNTCNAARAGYGCNATH ATHCARTAYTCNYTNTCNTGGGCNATHAAYCCNGARYTNGCNGCNAAYGGNGTNMGNGTN AAYGTNYTNGCNCCNGCNTTYGTNGAYACNCCNYTNGTNACNAGYYTNMGNAGYGGNCAR ACNTGYYTNATGCCNCARATHGCNGARAARATHATHGAYACNGCNATGACNCCNTCNTAY GTNGCNGARGCNATGATGGARYTNATH--------------------------------- ---MGNAARMGNMGNTAYAGYGAYGTNYTNGAR---GAYCCNTAYMGNGGNCCNCCNGAR TTYATGGARGCNGGNGCNMGNGGNTTYYTNGTNACNACNATHCCNGAYMGNGARGARCAY GCNATHGAYGARGCNGTNMGNTGYYTNMGNAARTCNTGYGTNAARYTNTTYGGNMGNATH AARCCNYTNAARMGNGARGAYGCNTCNTTYGCNAARGGNTGYGTNATGATHGAYTTYATG GAYCCNGARACNGTNACNATGYTNCCNCAYCCNGAYGCNGAYAARGCNGCNGCNGCNGAY AARGARAAYGTNGARGCNGARGCNGGNAARGARGARAARAARGAYAGYGARGCNATGGAR CARGARYTNAARCAY------------------------GAYGCNGARCARGARCCNGAR GCNGARAARGARAARATHGARGGNGARGAYACNACNGARACNAARGTNGARGARACNAAR GCNGARGARGGNACNGAYGTNAARGCNAARGARGARAAYGARCARGAYGARAARGCNAAR AARGAYGARGTNAARAARAARAARMGNGARGARGARGAYAARTCNMGN------------ ------------------------------------------------------------ ------------------CCNYTNATGTTYGCNCCNCAYAARTTYAARTGYTAYMGNACN GARYTNMGNAAYATHATGTTYGTNAARTCNGAYGTNGCNGAYCCNGGNGTNGTNGCNACN ACNGCNTTYGAYYTNATHYTNGAYMGNAARCCNATHTTYACNGAYTGYATHAAYCARYTN YTNCCNGTNCAYGGNGTNTGYGAYAAYGAYTAYAARCARYTNGARATHATGTGYMGNMGN GTNYTNGTNCCNTTYGTNGGNGARCAYYTNGARGARCCNCCNAGYTTYGGNGTNATGYTN GTNGAYAARATGTGYGARCCNGGNGCNGARGTNYTNYTNGARGTNGTNMGNAGYGCNATH TGGTGYYTNAAYCCNGAYGCNCAYCARMGNTCNCCNTGGACNGARCCNGAYGTNGTNGTN CAYATHGARATHATHGGNAGYAARATHATHYTNAGYGCNATGACNCAYTAYATGAARTAY MGNCARTAYAGYCCNTTYGCNYTNCAYGARYTNGGNCAYGGNAARCCNGARGAYGARGAR YTNYTNMGNGARCCNAARGARAAYAGYGARGAYGGNAARGAYAARGGNGGNMGNAARAAR AARAARGAYAAYAARAARAARGAYAARGGNGGNMGNAARAARAAYAARAARGAYAAYAAR AARAARGAYAARGGNGGNMGNAAR------------AARAAYAARAARGAYAAYAARAAR AARGAYGAYAARGAYAARGARAARAARGARGAYAARGARAARAARGARGGNAARGGNGAR ------------------GARAARGARAAYAARGARGGNGGNGGNGAYACNGGNAARGAR CCNGARGARAARGARAAYGTNGGNGARGAYGTNTCNACNGARGCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CAYGTNAGYGCNGCNGAYCAYGAYTGYATHYTNATHCAYGGNGGNGAR ACNTTYGAYGGNMGNAGYMGNGARCCNGTNGGNGARATGTTYATHATHTCNYTNGCNTCN CCNACNATHTTYTAYAARYTNAAYACNAGYAGYGTNMGNMGNGCNGGNCAYATHTGYYTN ATHTCNGAYGAYAAYATHTTYATHCAYGGNGGNTAYGCNGGNCARTCNACNGTNAAYTCN GAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARACNGGNGARAGYATH TGYAARGTNCARGGNCAYTGGAAYGGNGTNATGGAYTTYACNTAYGCNGAYGGNGGNGTN CARTCNGTNGAYGTNTCNCARYTNCARGTNATGMGNAARTCNGTNMGNCCNGTNGARAAR CARGARGARCAYGARTCNMGNMGNYTNTGGCARAAYGTNAGYCARGCNYTNAARGCNAAY GAYATGAGYACNGCNACNGARCAYAARMGNGCNYTNGARGARGCNCARMGNGARGGNGAR MGNCAYMGNAARGCNAAYAAYATHCCNTAYGTNGGNAARTTYTTYGAYAAYATHGAYGGN GTNTGGGTNCAYAARAAYYTNCCNMGNAAYTTYGGNCARGAYAARAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TAYACNGCNGTNGTNGCNGTNTCNCAYATGAAYYTNAARTGGTGG GCNGAYCCNTTYGCNGTNGGNYTNTCNGTNGTNYTNATGGAYGTNCCNTTYGAYATHATG GGNATHAARYTNYTNTTYTGGAGYTGGCAYGAYGAYGAYCCNAAYATHTAYGAYMGNCAY TAYTGGGTNCCNTGGACNTCNTAYTAYTTYCAYGCNGCNTTYGCNTCNTCNTTYGCNTTY ATHTTYTTYGGNATHAARMGNYTNTTY---TCNTCNGGNYTNAARTTYCARAGYAGYGGN TTYTTYYTNGARYTNCCNATHYTNGTNYTNACNGGNYTNTGYTCNACNCCNYTNGGNGCN ATGCARTTYATHCCNGTNTAYCAYCAYYTNCAYGAYGTNYTNGGNATHCAYACNGARGTN TGYGTNYTNYTNTTYYTNGGNTTYTAYGGNATHGTNGTNTGGAGYTCNGAYMGNMGNCCN YTNGARTTYGCNMGNCAYAARGGNGGNAGYATHTTYAGYYTNATHATGYTNGTNGTNGTN GCNCAYTAYGCNTTYTAYATHTTYYTNGTNYTNACNGCNAAYCCNACNGCNGTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AGYTCNAARCAYMGNMGN TCNMGNTCNGAYTCNMGNTCNMGNTCNMGNTCNACNTCNCCNAARAAR------------ MGNAGYMGNCAYTCNMGNTCNMGNTCNMGNGAYMGNMGNCAYAARMGNGAYMGNMGNAAR MGNTCNTAYMGNTCNMGNTCNMGNGARMGNMGNMGNTCNAARGARMGN------CAYMGN CAYAARMGNGARCAYAARMGNAGYMGNAGYMGNAGYMGNGAYMGNMGNGAYMGNMGNCAY GAYMGNMGN---MGNAGYMGNGARMGN---MGNMGNAGYMGNAGYMGNAGYMGNAGYMGN ---------MGNAGYMGNAGYMGNGAYMGNMGNMGNGAYAGYMGNAGYGGNAGYCCNCAY GAYGGNAAR------GTNATHAARTTYGGNGAYAARGTNATHAARGCNGGNGCNAGYTTY GGNMGNCCN------ATGTCNAAYTTYTCNAARCCNGTNACNTTYAARGARAARATGMGN CARCARYTNATHAARGCNATHGARGAYGGNGCNGAYACNAAYGARGTNYTNGCNAAYAAR GGNGGNTCNACNATHTGYACNCARTCNGCNGGNGTNGCNCARGCN------ATHCCNMGN CCNAARGGNCCNCCNGTNCCNYTNATGGAYACNATHGTNCCNTCNACNGCNAAYYTNGTN GCNATGACNGTNACNGCNTCNGARGCNGCNATGCARTCNATGYTNGCNYTNCARAARGAR GCNACNGARAARACNGGNGTNGARATHCCNAARTAYTAYAAYCCNGCNGCNATHAAYCCN ATGAARTAYGCNGARCARGTNCARAARMGNAARYTNYTNTGGTCNAARGCNAARGAYAAR GAYGTNAAYTCNCARTGGCAYGCNACNAGYYTNTCNGGNGAYGCNGAYGAYAARTCNAAR GARAARTTYMGNAARYTNATGGGNATHAARGARGAYCCNACNGGNAAR------------ ---------GCNGARGGNGARCARGARGARAARCARAARCARATHTTYGAYCARYTNAAY AARGARTAYGARTTYGCNMGNATGGCNACNCAYACNCAYMGNGGNATHGGNYTNGGNTTY GGNTCN---GGNTAYCARCARCCNCCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GCNAARTCNGARYTNAARCAYYTNCCNGCNACNATHAARGAY ATHAGYGCNATHTCNCCNAARGCNYTNGGNGTNATHGTNATGGGNGAYTTYAAYGCNGAY TGYAARTAYGTNAGYMGNAARGCNMGNTCNGARYTNGARATHTTYACN---AGYAARCAY TTYGTNAGYYTNATHCCNGAYAGYGCNGAYACNACNGTNTCNAARAGYACNGAYTGYGCN TAYGAYMGNGTNGTNGTNTTYGGNCAYGARATHGAYGCNMGNGARCCNGCNGTNTTYAAY TTYGARAGYTTYYTNMGNYTNAGYGAYGARGARGCNGCNGAYYTNAGYGAYCAYTAYCCN GTNGARTTYYTNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARAARAARMGNAARATGGARATGGAYCARACNYTNAGYGARGTNACNAARAAR ATHAAYGAYGCNAAYMGNYTNATHGARACNATGACNTCNYTNGARAARYTNMGNYTNATH MGNCARGAYGCNGCNMGNAARMGNGGNGAYTCNGAYGTNGGNGARTCNMGNGARAGYTTY GARCARAARATHTCNGAYATGACNMGNYTNGTNCARTCNCARYTNGARGTNTAYGARCAR GARGARCARAARYTNMGNAARGTNYTNAARTCNGARCAYGARGARTCNAGYAARATGGAR AARCARYTNCARGARAARAARGAYYTNGARGARCARAARCARAARGAYGAYGARYTNCAY MGNGTNYTNTTYGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AARMGNGARTGGAARGAYGCN YTNACNAAYGCNGTNCCNATGCCNCAYMGNMGNTGGGCNAARCAYTTYATHCARACNTGG MGNAARGARAAYATGAARAAYTCNACNAGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TGYAGYCAYMGNYTNACNMGNTGGAAY YTNTGGAAYGCNTAYCAYAAYMGNGCNTCNCAYATHCAYGCNAAYCARTTYYTNAAYAAY AAYAARYTNATHGAYAAYYTNMGNYTNTAYMGNGGNGAYGTNGCNGGNATHYTNGGNTAY GAYAAYTTYGCNGARATGTCNATGGARACNAARATGGCNGGNTCNGTNGARAAYGTNYTN AGYATGGTNGARACNYTNMGNGCNMGNTAYGCNCCNGTNGTNTGGGARGAYYTNGCNCAR YTNCARGAYTTYGCNACNTCNGARGGNTTYGARCAYAGYYTNGARATGTGGGAYGTNAGY TAYTGGMGNMGNMGNCAYMGNGARCAYYTNTAYAGYTAYGAYAARGAYGCNGTNAARGAR TTYTTYCCNGTNAAYTCNGTNYTNYTNGGNYTNTTYGAYYTNTGYACNAAYYTNTTYGGN GTNAAYTTYGARGARGTNACNCCNGAYGTNGARGTNTGGAAYCCNGAYGTNMGNTTYTTY AAYGTNATHGAYGAR---AAYGGNGARCAYATHAGYTCNTTYTAYTTYGAYGCNTTYGAY MGNCCNGGNAARATHTCNTCNGGNTTYATGGAYTTYGGNMGNGAYAAYAGYGARMGNGTN GGNACNTGGCCNTAYTCNTAYYTNTGYYTNAARGTNCCNMGNCCNAARTCNCCNTCNGAY CCNATHYTNATGMGNTTYGARGAYGTNGARATGYTNTTYACNCARTTYGGNCAYGGNYTN CARCARATGYTNACNAARGTNCCNTAYAGYGARATHGCNGGNCARAARAAYATHGARTGG GAYGCNGTNCARGTNTGYGCNAARTTYATGAARCARTGGYTNTCNGTNCCNAGYGTNGTN AARAGYYTNACNAGYCAYTAYAGYACNGGNCARCCNATHCCNGAYGAYGTNYTNTCNAAY ATGYTNAARGCNTCNAARCAYTGGAGYAAYTTYGAYATGATGTAYCARYTNTAYGTNTCN GCNTTYGAYATGGARATHTAYATGACNGAYACNCAYTGGYTNACNGTNATGAARCARYTN TGGGARAGYTTYATHCCNYTNCCNYTNATGGARGARGAYAAYYTNCCNTGYTCNATGYTN CCNATHTTYTGYGAYGTNTAYCCNGCNGCNTAYTAYTCNAAYAARTGGTCNGARATGGTN GCNACNGAYYTNTTYTCNGCNTTYCARGARGCNGGNYTNGAYGAYCARGARAARYTNAAR GTNYTNGGNMGNNNNNNNNNNGAYACNTAYYTNTCNYTNGGNGGNGGNGTNTCNGCNAAY GARGTNTTYMGNCARTTYMGNGGNMGNGAYCCNTCNACNCARGCNYTNCARCCN------ ------------------------------------------------------------ ---------------------------------------------------------MGN MGNMGNCARGTNMGNAARGAYGTNAAYCCNGARGAYGARACNGGNAARGCNGCNATHMGN MGNAARGCNTGGGAYCAYYTNGARGAYAAYAAYYTNGTNTCNGCNCCNMGNCCNTGYCAY TAYMGNATHCCNAAYTTYGARGGNGCNGCNGCNGCNGCNGAYMGNYTNACNGCNYTNGAY GARTTYAARAARGCNCAYACNATHAARGTNAAYCCNGAYAARGCNCARGARCAYGCNMGN TTYYTNTGYYTNGARGCNGARAARGARYTNGTNYTNYTNTAYCARAAYCARAARGARYTN ATGGTNCCNACNCCNGARYTNAARTCNGGNYTNYTNAAYMGNGTNACNCCNCCNGARGGN GCNACNAARGAYGAYYTNAARCAYTGYTGYACNACNCARGGNGTNAARGARAAYAGYAAR GARATHGGNYTNGAYGAYAARGTNAARYTNGAYYTNATHGTNGTNGGNAGYGTNGCNGTN TCNMGNAAYGGNTAYMGNATHGGNAARGGNAARGGNTAYGCNGAYYTNGARTAYGCNATG ATGMGNACNYTNGGNGCNGCNAGYGCNGAYACNGTNGTNGTNACNTCNGTNCAYGAYTCN CARGTNGTNGAYATHCCNGARGARYTNGTNGAYGARCAYGAYATHACNGTNGAYTAYATH YTNACNCCNACNGARGTNATHAARACNAAYTGYAGYMGNCCNMGNCCNACNGGNGTNATH TGGAAYCAYYTNGARGTNAAYAARTTYTAYCARATHCCNGTNYTNMGNCARYTNMGNAAR AAYGARMGNGAYGCNGGNAAYGARGTNYTNYTNAARGAYCARAARGARGARGAYGARGAY CCNGTNGAYGCNATGGARCCNCCNMGNCCNMGNMGNTTYATHMGNTAYTAYCARAAYGCN GGNGGNTAYMGNGGNMGNGGNGGNMGNTTYGGNGGN---CARMGNMGNGGNGGNMGNMGN MGNCCNTAYGAYGAYAAYGGNGAYGAYAGYAAYAARGARAAYATGGAYGGNGGNGARGAY TCNGGNGCNGAYGGNGAYAAYGARGGNMGNGGNAAYAGYMGNAGY--------------- AAYTTYMGNAAYMGNMGNTAYMGNMGNGGNGGNGGNGGNAGYCCN---MGNGCNTCNGAR TCNGARCAYAGYGAYGGNGCNGTNGAYGGNAAYMGNGARGAYGGNGAYGAYMGNCCNMGN MGNMGNTTYACNACN---AAYMGNMGNMGNTTY------------GCNMGNMGNMGNMGN TTYGARGGNAAYMGN------MGNGAYAAYMGN---MGNGAYGAYCAYTCNGGNAGYGAY GGNGARCARAARAAYTCNGCNGAYGARGGNGAYGAYGGNMGNMGNCARCARMGNCARMGN TTYMGNACNAAYCCNGAYGCNGTNGTNTTYATHGGNGCNYTNGCNMGNACNYTNMGNGTN AGYGARYTNAARGCNCARYTNMGNAGYAARAAYATHAAYCCNTAYMGNGTNYTNTGGMGN GGNGGNMGNGGNTAYGCNTTYYTNTTYTTYCARTCNACNGAYGAYGCNAARGARTCNGTN CARYTNYTNTCNGGNCARGARYTNTGYGGNMGNGARATGAARGTNGARATGGCNAAYATG GAYMGNGAYMGNGAYTCNMGNMGNMGNACNAAYMGNACNGAYAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGCCNGGNACNCARGTNTTYGAYAARTCNGGNMGNTCNYTN AAYYTN---------GTNCCNYTNGGNGAYATHTTYGCNTCNGCNCARTTYAAYGARTAY GCNYTNCARAAYATGGCNGAYTTYCCNYTNMGNGARGAYGAYGTNATGYTNGTNAGYTAY CCNAARTCNGGNTGYCAYTGGGCNTGGGARATHYTNMGNATHYTNGTNCARGGNACNYTN AARGAYGAYAARYTNGAYAARACNCAYTGYATGATGGAR---------CCNCCNGARMGN TTYGCNTCNYTNTCNTCNCCNMGNGTNYTNAAYAAYCAYATGCCNTTYGGNATGCARCCN AARCARATGYTNAGYAARAARCCNAARGTNGTNTAYTTYTAYMGNAAYTTYAARGAYGTN GCNGTNTCNTTYTTYCAYCAYCAYAGYGGNATHAARGARTAYGGNTAYMGNGGNGAYGAY TTYGGNGCNTAYYTNCARMGNGTNGTN--------------------------------- ------------------------------------------------------------ ------------------GAYGGNYTNGTNGARGGNGGNAAYCCNTTYAARTAYACNMGN GAYTGGGARMGNGGNATGGARCARCAYCCNGAYYTNCCNGTNTAYTGYTGYGCNTAYGAR GAYATGAARAARGAYCCNATGAARGARATGMGNAARYTNTGYGARTTYYTNCARGTNGAY MGNAGYGAYAGYTTYYTNCARMGNGCNTGYGARGTNACNAGYTTYGAYAGYATGAARAAR ACN---------------YTNGGNGCNATHACNCCNGTNTTYTAYMGNAARGGNCARGTN GGNGAYTGGGTNAAYCAYTTYACNGTNGCNCARAAYGARTGGTTYGAYGGNYTNATHGCN TCNGARATGGCNGAYACNAAR------------------YTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNGARAAYAARTTYATHAAR GCNCAYATHGAYCCNATHGGNMGNGTNACNTCNYTNAARTGYTTYGAYCAYAAYGCNGAY MGNGTNTGYAARGARGCNGTNGAYCCNAARCARCCNGCNAAYCARTTYGTNGTNTAYGAY GAYATHCCNYTNTTYTGGGAYGCNTGGGAYGTNATGGAYTAYCAYYTNGARACNMGNAAR CCNYTNTGYCARYTNGTNGARGTNATHGARAAYAARGAYCCNCAYMGNAGYTCNYTNACN TTYAGYATHAARATHAGYGARGAYAGYCAYATHAARCARGARATHGTNYTNGAYGCNAAY TGYCCNTAYYTNMGNTTYAAYACNGARGTNATGTGGAARGARAGYCAYAARTTYYTNAAR GTNGARTTYCCNACNACNGTNCAYTCNATGGARGCNTCNTAYGAYATHCARAGYGGNTTY TAYACNMGNCCNAAYCAYTTYAAYACNTCNTGGGAYTGGGCNMGNTTYGARGTNTGYGGN CAYAARTGGGCNGAYATHTCNGARCAYGGNTTYGGNGTNAGYATHYTNAAYGAYTGYAAR TAYGGNTAYTCNGCNATGGAYGGNGTNATHMGNYTNTCNYTNYTNMGNTCNCCNAARAGY CCNGAYCCNACNGCNGAYATGGGNGTNCAYAARTTYTCNTAYGCNATHATGCCNCAYCAY GGNACNTTYCARGARGCNGGNGTNATHCARCARGCNATGGGNTTYAAYTGYCCNYTNAAR ACNGGNCCNAARGCNATGCCNACNTTYCCN------------------------YTNTTY AARAGYAGYACNCCNCARGTNACNGTNCARACNGTNAARATGGCNGARGAYMGNAGYAAR GCNATGGTNYTNMGNYTNAAYGARGCNTTYGGNGGNCAYGTNACNGCNMGNATHGARTCN TTYGTNAAYATHACNGGNGTNAARGTNTGYAAYGGNYTNGARGARGCNTCNAARGARGAY GAYYTNAGYYTNGARGTNAARMGNATG------GAYTCNYTNACNATHATHAGYYTNAGY YTNAARCCNTTYCARATHGTNACNYTNAARTGYAGYYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNTTYYTNMGNAAYTTYGAYTGYGCNATHAARMGNTTYAARMGNGCN GAR------------GAYTGYCARGAYCARATHCAYAGYGARYTNTCNGCNYTNYTNAAR TAYCARCAYGARAAYATHGTNACNYTNTAYGGNTAYACNCARGAYGTNMGNGCNCARTGY YTNGTNTAYGARTAYYTNAARAAYGGNTCNYTNGARGAYMGNYTNYTNMGNAARAAYGAY ACNCCNGTNYTNTCNTGGGARMGNMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGGCNGCNCCNATHGCNACNTAYGGNAGYAARATHAARGTNAARAAYAAY AAYGTNTCNYTNCARGTNGGNAARGGNTCNTCNYTNACNCAYCCNTCNAGYATHGCNAAR AARYTNCARMGNGARTCNGAY---------GGNYTNTGYYTNGARGAYMGNATGGCNGTN GARCARTGGYTNGAYTTY------------AGYGGN------------GARGARAARGAY GGNGAYMGNGAYAARATHCAYGCNATGYTNAARGAYYTNAAYMGNTTYATGAARGAYMGN GTNTAYTTYGTNGGNTCNGCNYTNACNATHTCNGAYGTNTTYYTNTAYCAYAGYYTNTTY CCNATHATHGARAARYTNACNTTYCAYGARAARGARMGNYTNATHCAYYTNTCNMGNTGG TTYAAYCAYGTNCARAGYGAYAARAGYGCNMGNCARTCNYTNYTNCCNGTNAARTTYYTN MGNACNGTNYTNTAYACNGGNGTNGGNAAYCAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GAYAARATGATHAARACNGTNGCNGTNTGYGCNGGNTCNGGNTCNAGYGTNYTNAARCAY ACNAARGCNGAYYTNYTNGTNACNGGNGARATGTCNCAYCAYGAYGTNYTNGAYGCNGTN CAYACNGAYAARAAYGTNATHYTNTGYCAYCAYAGYAAYACNGARMGNGGNTTYYTNMGN GARYTNCARAARACNYTNGCNAARTCNATGGARAARCCNGTNCARGTNATHGTNTCNGAR ACNGAYMGNGAYCCNYTNGARATHGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CCNAARTAYYTN GGNGTNACNYTNGAYMGNAGYYTNACNTAYTCNCAYCAYACNGARGGNACNGCNMGNAAR ATHAAYAARMGNAAYTGYYTNATGMGNAARYTNGCNGGNACNACNTGGGGNGCNAGYCAR ACNYTNYTNMGNACNACNGCNYTNGCNYTNTGYTAYAGYGCNGCNGARTAYTGYGCNCCN GTNTGG------AAYMGNAGYGCNACNGTNGGNAARATHGAYGTNAARYTNMGNGARTCN ATGMGNATHGTNACNGGNTGY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TGGGTNACNGGNYTNMGNCCNGTNCCN GGNGTNTGGAARTCNTGGAAYGARGAYGGNYTNGARGGNAGYCARACNAAYMGNGARAAY GARACNGCNAARAARATGYTNGARGCNGCNGCNYTNAAYAARAARGTNGARGTNAGYYTN GAYATGGARTCNTTYGCNAARGTNATHGAYAARYTNGGNTCNGARMGNGAYTCNACNCCN CARGGNAAYATGTCNMGNGARATHACNAARACNACNMGNTCN------GCN------CCN TCNMGNGGNAARYTNGCNYTNYTNAARCARGARTCNCAYCARATHGGNCCNGGNCCNGAY TAYGARMGNGTNAARTTYAAYACNTCNGGNMGNAGYCCNYTNATHGCNCAYTAYYTNCAY ATGMGNCARYTNMGNAGYTAYAARCARCCNGGNATGAARGTNMGNMGNACNGARATHYTN AARYTNCCNCCNGAYGGNCCNACNTAYCARCARTTYATHGCNACNACNYTNAGYAARGCN GARGCNYTNGARAARGARTAYACNMGNATHTGYGAYCARACNTCNACNGCNATHYTNGAY YTNGARMGNAAYAARMGNGAYTCNAAYAARGARATHACNGARYTNCARAARGCNYTNACN AAYGTNAARAAYGCNCCNGARMGNMGNTCNYTNATGGAYAARATHTCNGARTAYAARGAY YTNGTNATHAARGARAARCCNYTNYTNGARGTNTCNATHTCNCARACNGAYAGYGCNTCN TTYTCNTCNAGYGAYTAYGAYGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARYTNCARAARCCNAARTAYGAYCCNACNTTYTTYACNYTN CCNCAYCCNGCNYTNGGNGGNYTNACNYTNTCNYTNYTNATHTAYYTNGCNGTNACNACN YTNTGYCCNGAYATHYTNCCNGAYTTYYTNTGGCCNTTYGCNCARYTNGGNAARTAYATG GGNAAYCARCARTTYAAYGCNTGYATHGCNATHTGYTTYTTYACNYTNATHGCNCAYAGY ACNGARGCNGCNTAYGCNGGNAARGTNTGYCAYGAYMGNMGNTAYCAYGTNTCNACNACN ATHAARTGGACNYTNTCNACNTTYYTNTTYGGNTTYCCNTCNATGATHMGNYTNYTNCCN CAYAARCCNMGNTCNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARMGNGARMGNGAYTTYGARTCNACNMGN------CCN GCNGARGGNTGYATHGGNAARGTNATGGAYATHTTYTTYYTNYTNGAYTCNTCNTCNTCN ATHTAYATHAAYGAYTAYATGTCNCARCAYMGNTTYGTNMGNGAYGTNATHAGYMGNTTY GAYATHAGYCCNCARAGYACNMGNGTNGGNATGYTNACNTTYAGYGAYGAYYTNGARMGN CCNGTNATGGGNYTNAAYMGNTAYTCNMGNAARAGYGAYGTNYTNGCNAGYATHTCNATG CARAAYYTNCCNTAYMGNACNGGNGTNACNAAYACNGAYYTNGCNATHMGNCAYGTNMGN CARATGCARGAYTTYMGNCARGAYATHACNAARGTNATGGTNGTNATGACNGAYGGNGGN TCNMGNTCNTCNGGNACNACNGCNMGNGARGCNGARYTNGCNMGNAAYGCNGGNTTYTAY ATGTTYGTNGTNGGNATHGGNCARTAYYTNGARGARMGNGARTGGMGNTCNATHGCNAGY GAYCCNGAYGAYTCNTTYATHTTYAAYATHACNAAYCCNMGNTTYTTYCARGAYGTNAAR TAYTCNYTNCCNCCNMGNGCNTGYGCNYTNCCNCCNATHATHYTNGGNGGNTCNTGYAAY GTNGGNCARGTNGCNGARGTNTAYTTYGTNGCNTCNMGNAGYGCNAGYAGYAARGCNATH GAYATHATHGARAAYTTYAARMGNMGNAGYMGNGAYGAYMGNGARAGYYTNMGNYTNAGY TAYATGATHGARGCNTGYGGNTCNGTNACNAAYACNCCNYTNGAYGAYGARGAYGTNTAY ---TGYGAYMGNTTYTCNTCNMGNACNGGNGAYACNGCNGARTCNGTNTCNGCNYTNTTY AAYMGNGCNMGNGCNGTNGCNMGNGAYTCNMGNAAYGAYGCNGARTCNACNCARGTNATH GTNYTNTTYGTNGAYGAYGARACNATGTCNYTNGCNMGNTTYGAYTGGTCNACNACNGCN MGNACNACNTCNAAYTTYGARGGNGTNAARGTNATHGTNGTNGAYYTNGGNYTNMGNACN TAYMGNGAYTTYGCNCARMGNATGGTNACNTCNMGNAAYGAYYTNGTNAAYTTYCARGGN AGYGCNGARGAYMGNMGNTCNGGNAGYCAYACNGCNTTYATHGAYACNACNTGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYGAY------GCNATGCCNCARGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNATHGAYYTNATHTAY TGGMGNGAYGTNAARACNACNGGNYTNGTNTTYGGNGCNATGYTNGTNGTNYTNYTNTCN YTNGCNATHTTYTCNYTNYTNAGYGTNGTNGCNTAYYTNTCNYTNGCNGTNYTNACNGTN ACNTTYAGYTTYACNGTNTAYAARAARGTNATGGGNGCNGTNCARAARTCNAAYCARGGN CAYCCNTTYAARCARYTNATHGGNYTNGAYATHACNYTNAGYGARGAYAARYTNAARAGY ATHATHCARAGYTTYYTNAARAAYGCNAAYTGYACNATHAGYGARYTNMGNMGNYTNTTY YTNATHGARGAYATGGTNGAYTCNATHAARTTYGGNYTNYTNYTNTGGGTNYTNACNTAY GTNGGNGCNTGGTTYAAYGGNATGACNYTNGTNATHYTNGTNGTNATHTGYATHTTYACN YTNCCNAARGTNTAYGARACNTAYAARGTNCARATHGAYAAYTAYATHGGNATGGCNAAR GCNCAYATHGAYAAYGTNYTNAAYATHGTNCARAGYAARYTNCCNTTYYTNAARAARAAR GARAARGCNCAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNGARAARTCNGAYYTNATHYTNYTNACNTCNGGNTAYTTYAAYYTNACNGAY CARTAYGCNGAYGTNATHGTNGAYGAYGCNGARGCNAARTTYAAYATHYTNATGGCNTCN CCNAARGCNAAYGGNTTYYTNGGNGCNMGNGGNGTNGCNGGNGCNGTNCCNTAYTCNTAY ATHTAYYTNGCNAAYAARTTYCAYGAYAARGTNTCNMGNGCNGAYCARGCNCARMGNATH CAYATGYTNGARTAYGARMGNGARGGNTGGACNTTYCAYAGYAARGGNYTNTGGTAYTAY YTNAARAAYGARCCNYTNCCNMGNYTNACNYTNATHGGNTCNCCNAAYTTYGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGNYTNCCN GGNGARGARGTNGGNGGNGCNGGNCARTCNGCNACNCCN---AGYCCNTCNTAYTCNTCN AGYGGNCARCCNGTNGTNTCNAGYATGATHMGNGAYCCNGAYCARACNACNYTNTGYTCN MGNGAYCARGARCCNGCNCCNYTNYTNTCNGCNCARTAYGARACNYTNTCNGAYGAYGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNAAYCCNAAYAARACNMGNGCNGCNGTNGTNYTNCAR ATGAAYTTYAARGGNAARATHCCNMGNAARYTNGTNGARACNAAYTTYCCNAAYACNTTY ATHCAYTCNCAYGARTGYTAYATHAARTAYYTNAARAARAARGGNYTNTTYATGTGGMGN TCNCAYACNTTYMGNAARGGNMGNCARATHYTNACNYTNGCNAARAARCAYYTNGCNACN GARGCNAGYGGNGCNAGYGCNACNCCN------CCNCCNCCNCARCCNAARTCNMGNGGN TTYGGNYTNGTNAARTTYATHACNYTNGGNGTNCCNYTNGCNACNGGNGGNGTNGTNGGN TAYGCNTGGTAYGAYAARGAYTTYMGNAARCARGTNGARGAYAAYGTNCCNTAYGCNAAR GARGTNTTYGARAAYGTNYTNCCNGTNGAYGAYTCNCCNGTNGCNMGNACNTTYCCNAAR AARCCNGARGTNACNCCNACNMGNGGNAAYGARTCNGGNYTNGTNCAYAARGARGAYACN TCNMGNGAYGAY---------------------GCNTCNGGNAARCCNGAYAGYTTYACN GTNACNAARACNGARAARGARAGYAARGTNGAYGCNGTNACNATHCARCARCARATHMGN AAY---AARGARGARGARGARMGNGCNGAYAAYGCNGCNYTNGARGTNGCNATHGARAAR YTNATGGARTCNGGNCARAAYTGGGTNTCNGARGCNGCNMGNGCNCARATHGAYGTNGCN AARGCNACNYTNAAYCAYTGYAAYYTNYTNAARAARGCNATGGAYGAYTCNTCNGAYATH YTNGGNAARGAYACNCARTGGGARGCNGTNACNGTNGCNTTYAARGARMGNGARATHGCN ACNACNMGNGCNAAYGARYTNGTNGAYGARGCNMGNAARAGYATGGARAARYTNAARAAR YTNGTNGAYGARGCNMGNGARAAYAARAGYACNTCNAARAAYCCNGCNATHCAYCCNGCN ACNAARAARYTNGCNGARYTNAGYAARGARATGTCNAARGCNAGYGCNCARGTNMGNCAR GCNGAYGCNGAYGCNAARGTNATGTTYAARTAYAARGAYYTNGTNGAYAARGGNMGNAAR CARTTYCARCARGARYTNGARAGYYTNYTNCCNGAYGCNAARTCNGGNGGNAARAGYMGN AARYTNACNGARGARGARYTNAAYGCNYTNATHGCNCAYGCNCAYMGNMGNATHGARCAR YTNCARAARCARATHGCNGARCARYTNGCNATGGARMGNCARMGNYTNTCNGTNGCNYTN GAYACNCARAARGARGARAAYAARGGNATHACNGAYTCNGCNYTNGCNGAYGARMGNGCN MGNYTNYTNAAYGARTTYAAYGTNGARAARCARAARYTNGARATGGARYTNATGGTNCAR ATGGARYTNGAYGTNMGNMGNCARYTNAGYMGNCARGCNGCNGCNCAYAGYGAYCAYYTN AARGAYGTNYTNGCNGTNCARGARGGNGARATGAAYAARGARTTYGARMGNAARATGAAY ATGGCNYTNYTNGARGARMGNGARAARTTYCARGARGARACNTCNGGNTGGATHTCNMGN YTNAARGGNATHGARGCNGCNGTNGAYGCNMGNGCNGCNAGYGARCARYTNGCNMGNACN GCNCARGAYYTNTGGYTNGCNTGYATHGCNYTNAAYTCNACNATHYTNTTYGGNAGYGAR GARGARGAYAAYTCNYTNATHCCNYTNCARCCNCARGTNCARGCNGTNGTNGAYTCNGCN AAYAARCAYCCNTTYGTNGARACNATHGCNAGYACNATHCCNAARYTNGCNYTNGARMGN GGNGTNTAYACNGARAGYAAYYTNMGNGAYMGNTTYGTNAARGTNGCNCARATHAGYMGN MGNYTNGGNYTNGTNCARGARTCNAAYGCNTCNYTNTAYAARTAYYTNGTNTCNTTYYTN CAYTCNTTYTTYACNGTNAAYAAYGTNGCNGCNCAYTCNGARAARGAYYTNATHTCNYTN GAYGARATGGAYAAYTTYAARYTNGTNGCNAAYGCNCARTAYTGGATGGARAARGGNAAY YTNGARATGGCNYTNMGNTTYATGAAYCARYTNACNGGNCARTCNAARAAYGCNGCNAGY GAYTGGGTNACNGARGCNMGNYTNYTNYTNGARACNMGNCARGCNGCNCAYACNGTNATG ACNTTYGCNTCNGCNACNGGNYTNGCNGCNACNTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYAAYYTNGAYACNCCNTAYMGNAARYTNTCNMGNYTNTCN GAYTCNTCNTCNGAYTCNGGNTTYAGYGGNAARGGNTTYAGYTCNTCNTCNTCNTCN--- ---TCNTCNTCNTAYTAYGCNGCNGAYAGYCCNTCNGGNTCNTCNGTNGGNAAYAGYTCN ACNAAYTCNAAYGAYACNGARAAYGAYCCNCAYGGNTCNMGNGTNYTNGCNCAY---ATH GCNCAYAAYCAYACNTAYAAYACNYTNCCNGGNCAYGTNCCNMGNGARGTNAARAARTAY GCNCCNAARGTNAAYACNAARAARGGNCCNATGTGYMGNGAYGCNAARMGNGCNCARGAR ATGAARATHCCNYTNACNGTNGARGARATHGTNGAYTCNCCNGTNGARTCNTTYAAYGAY YTNYTNACNAARTAYAGYYTNAGYGARGARCARYTNACNYTNATHMGNGAYATHMGNMGN MGNGGNAARAAYAARYTNGCNGCNCARAAYTGYMGNAARMGNAARGTNGGNGTNATHGTN ACNYTNGCNGAYGARATGGAYGARYTNCARAARGTNMGNGAYMGNYTNAARTTYGARMGN GCNGARATGGARMGNGARACNMGNMGNATGAARGARAARTTYAGYCAYYTNTAYACNCAY ATHTTYCARTCNYTNMGNGAYGARCARGGNCARCCNTAYGAYACNAGYMGNTAYTCNYTN CARCARTCNAGYGAYGGNAAYGTNTTYYTNGTNCCNMGNAAY------------------ ---ACNACNACNACNGGNGCNGCNACNAAYGGNACNACNACNAAYGGNACNMGNCCNAAY GAYACNGGNMGNACNAARAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GGNAARAARGGNGGNGTNYTN ACNGAYGCNACNACNGCNCARGAYGTNGARGCNTAYAARTAYYTNTAYTCNAAYMGNGCN TCNTTYACNGGNCCNATHAAYTAYATHMGNGCNGCNCARYTNTAYGGNAAYTCNTCNMGN YTNTCNCARAARGTNTCNAARCCNGTNYTNYTNATHTGGGGNTGYMGNGAYYTNGCNYTN GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AAYCCNYTNTTYATHTTYTCNGAYGTNCCNTTYGAYACNYTNTCNYTN GTNTAYYTNACNGGNGGNTGGGTNMGNATHTAYTTYACNMGNACNACNAGYTGGYTNACN GCNATGATHTCNTTYGARMGNTGYYTNTGYATHATHATGCCNYTNAARGTNAARTCNATH GTNAGYMGNAARMGNTCNATHTAYACNATHATHACNATHTTYTTYAGYATGTCNYTNACN ATGCCNAARACNYTNYTNGGNYTNGTNTTYACNGARGAYMGNCCNATHGTNTAYAAYGGN ATHATGGGNGCNAAYYTNATHYTNGCNTTYGCNTCNTTYTTYTGYGTNATHGGNTGYACN CCNYTNYTNGTNACNMGNYTNAAYCARAARGCNAARTGGMGNGGNGARTCNGTNAARGGN CARGAYGCNYTNGARACNATHACNACNMGNGAYCARMGNGTNAGYAARATGGTNATHATH ATHTCNTCNGTNTTYATGGGNTGYYTNYTNCCNGGNGTNATHYTNTCNATHGTNATGYTN TTYGTNCCNGARTTYAGYAARGGNMGNGGNTAYCAYAAYYTNTTYACNATGGTNTGGGCN GTNAAYCAYATHACNGARGCNATHAAYTCNTCNGTNAAYATHTTYATHTAYTAYAAYATG AGYAAYAARTTYMGNTGYACNYTNMGNGCNATGTTY---------AARYTNGCNCCNYTN GTNMGNGCNYTNCCNMGNYTNAGYAAYGCNMGNTCNATG---AGYGGNCAYGGNACNCCN GCNCAYTTYAARTCNCCNTAYGARGTNTGYYTNGARACNMGNAGYCAYATGAARTTYATG CCNGTNCCNGARGGNTCNTGGCARGCNGCNCAYACNGCNAARAGYAAYTAYTAYAAYAAR YTNATGGCNGTNAGYYTNGCNYTNTTYGCNGCNACNTTYGGNTAYYTNTTYGCNACNGAY GTNATHTAYYTNCAYGGNCCNCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CARGCNMGNAGYAAR---------------GAYAGY ATHAGYTCNTCNCCNCCNCCNMGNACNTCNACNCCNYTNCCNGTNGTNMGN------ATH GGNTCNMGNAGYACNACNCCNGAYCCNGTNAGYMGNGARGGNACNGTNTTYACNCCNACN GCNGAYAARGARYTNGARGCNATHYTNAAYMGNGAYGARGARGTNGARAGYGTNAGYGAR TCNACNAGYGGNAARTCNMGNCCNGTNACNGARGGNTCNGARGARGAYGARAAYGARGAY GAYCARGAYAAYGARGAYGCNGCNGAYGAY------GGNTCNAARGTNGTNTCNMGNATH ACNATHACNAARGCNGAYGAYGAYMGN---AAYAAYGAYTAYCARAAYGAR------AAR AGYAGYACNAAYCARYTNGARATHAAYCARYTNAGYATHCCNMGNAGYCARGCNGGNTTY YTNTCNCARATGGGNTCNGCNGCNGAYTTYAARGGNTCNMGNYTNACNGTNAGYCARTTY TCNGGNAARMGNTCNATHATHAGYMGNGARAGYYTNMGNGARMGNGARAARYTNAAYGCN GARGTNAAYACNATHTAYGCNGAYYTNAAYGCNMGNTAYGCNGAYATGGTNCARCAYYTN GCNAARATHGAYAARGGNYTNAAYACNAARGGNTCNTCNGCNGARTCNAGYAAYGTNTCN AAYGTNGGNGCNAAYCAYATHGCNMGNYTNAGYCAYCARGARATHGTNGAYACNATHAAR GARYTNGARAGYATHCAYTCNGCNMGN---CARGARAARGARGGNGARGARGTNATHAAY GAYGARACNGTNATHGARATHGARMGNGCNGARGGNAAYGAYGARCARAARGARACNGGN GARGARAARGTNGGNGAYGARGARAGYGTNGGNGAYGAYGARGGNAARGAYGAYCCNAAY GCNGARTGGAARTCNTTYGTNGAYACNYTNTCNAAYGAYAAYACNGCNGAYGAYGARACN ACNTAYCCNTTYCAYGARGARAAYGGNAAYTCNATGATHAGYACNACNGARAAYACNGGN MGNGAYTCNGARTGYGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHGARYTNYTNGAYCAYMGNGGNAARGTNTCNTGYYTNGAYTTYACN AARGAYGGNYTNCARYTNYTNTCNGCNTCNCARGAYGGNACNGTNAARYTNTGGGAYYTN ACNAAYGAYGGNAAYATGTAYCAYACNTTYAARATGCAYGTNAARTTYTAYGGNTGYAGY TTYTCNCCNAAYGGNAARTGGATHGCNGCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGATHGTNGTN--------------------------------- ---------YTNGCNGARTTYGARAAYATGCCNCARGGNGTNAARACNTCNGTNGARGGN YTNMGNCARGAYATHTTYAAYGARCCNCARMGNTGYTGYTGYYTNGTNGCNCARACNGGN GGNAAYGARGGNGGNAGYATHATHGGNTTYGCNATHTAYTTYTAYGCNTAYTCNACNTGG GARMGNACNTTYATHCAYYTNGARGAYYTNTAYGTNAARCCNGAYTTYMGNGGNMGNGGN GTNGGNAARAARYTNTAYCARACNGTNGCNCARAARGCNYTNGAYATGGGNTGYACNMGN YTNGARYTNGAYGTNYTNGAYTGGAAYAARACNGCNAARGAYTTYTAYGARAARATHGGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CAYCARTCNCCNMGNTCNYTNAAYTCNTCN GGNGCNTCNGTNTCNTCNGCNYTNGTNGTNCARCARCARAAYGARAAYATHACNCARYTN GARAARCARYTNGARAARGARMGNGARGARAAYCARMGNYTNAARCAYGARATGGARGAR AARGAYAARAARATHGCNGARYTNGARAARTCNYTNGARYTNYTNAAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG TCNGCNACNATHTAYTGGGGNGARATHCCNAARGTNTCNGAYACNGAYTCNGGNATHGCN GCNYTNGARMGNGARCARATHACNAARCCNAARCCNATGGAYGTNGARGGNCAYYTNYTN CAYCARCCNTCNAAYMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CARTGYMGN ACNGCNCCNGGNGTNCCNYTNAAYCARTCNGTNCCNGGNMGNGCNTCNGAYGGNAGYTGG GARTAYGAYTCNTGYYTNCARTAYGTNGAYTTYTCNCARGGNAAYCARACNGARGAYTGY ACNMGNGGNTGGGAYTTYCAYTTYGAYGAYGAYGAYACNAARTCNATHGTNTCNGARTTY ACNYTNACNTGY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATGCAYCCNTAYTAYTAYGTNCARTAYGTNCCNATHCCNYTNAARCARGAYYTNGAR ATGAARGTNAAYTGGGCNGCNTCNCCNAGYACNGCNCCNAARCARGAYACNAGYAARCAY TTYCAYGTNTTYGTNGGNGAYYTNAGYTCNGAYATHGARCARCAYCARYTNMGNGARGCN TTYTCNYTNTAYGGNGARATHTCNGAYTGYAARATHATHMGNGAYCCNGCNACNATGAAR TCNMGNGGNTAYGGNTTYGTNTCNTTYGTNAAYAARTCNGARGCNGARACNGCNATHTCN GGNATGAAYAAYCARTGGYTNGGNACNMGNCCNATHMGNACNAAYTGGGCNTCNMGNAAR CCNYTNGCNCCNGTNGTNAARGAYAAYGCNAARCCNYTNGCNTAYGAYGARGTNTAYAAY CARTCNAGYTCNACNAAYTGYACNGTNTAYTGYGGNGGNGTNCARAAYGGNYTNTCNGAR GARYTNATGMGNAARACNTTYTCNCARTAYGGNACNATHCARGARGTNMGNGTNTTYAAR GAYAARGGNTAYGCNTTYATHMGNTTYAGYACNAARGARGCNGCNACNCARGCNATHTGY ACNGTNCAYGGNACNTCNGTNAAYGARCARCCNGTNAARTGYTCNTGGGGNAARGARTCN AAYGARTCNGGNCARGCNAAYCARCARTCNAAYAGYCCNCCNGTNGTNATGGTNCCNTCN CARCARCARCARCCNATHGCNGCNACNCCNGCNGCNGCNCCNTAYGGN---CARTTYTAY AAYATGAAYTAYTAYCAYGGNGCNCCNTAYGCNGCNGGNACNCCNACNTAYCARAGYGCN GTNCCNGCNCARGGNCARTTYATHCCNACNGCN---GGNCARTGGCCN---AGYTAYTCN AAYTAYCARGCNTAYGGNAGYATGAAYATGCCNATGGGNCARTAYGCNGGNYTNCARATG CARCCNGGNAGYCARCARCARCARTTYACNAGYCARGGNCARGGNATGGTNGGNTAYCCN ATGCARCARGGNATGGCNMGNTCNAAYGTNMGNTAYGARGTNYTNCCNTCNGARGARGAR MGNGTNGCNGCNGARCCNGTNGARGTNGCNATGACNATHCCNCCNCCNGARTAYACNGAR AAYGCNGCNGTNGARCARGAYGGNGAYACNCCNGCNTAYGGNCCNGCNAARYTNCCNAAY TAYGTNGARGCNACNACNYTNCCNTCNTAYGARGARGCNGARMGNACNAARGTNGARGAR GARGCNGTNTCNGGNGGNMGNTCNAAYGAYYTNGARGCNGGNMGNATGACNGGNATHGAY GGNGTNAAYGARGCNACNATHGGNACNGAYGGNATGTTYATHTGYACNTTYTTYATHTCN TTYYTNTTYAAYTGGYTNGGNTTYYTNYTNTCNYTNTGYYTNTCNAAYACNATHGCNGGN MGNTGYGGNGCNYTNTCNGGNYTNGGNYTNTCNATHGTNAARTGGGTNGTNATHGCNAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYGARGAYMGNYTNTCN GAYTTYYTNGARGARCCNTCNTGGGAYGAYYTNAARACNACNCCNYTNTCNCCNGCNAGY AARYTNCAYCAYYTNYTNGTNGARTCNCARGARATGATHMGNTCNYTNGARAAR---TCN CARGARCAYGARATHGAYYTNGTNGARMGNGAYCCNAAYAAYYTNAAYGAYCAYGTNMGN GTNTGYTTYGAYGARGTNATHGGNGARCCNGAYGGNGCNCAYTCNATHAAYTGYGTNTGG ACNAAYTCNTAYAARTGYTTYAAYTGYTGGAARAGYTGYTGYTAYAAYYTNYTNACNATH TTYTGYGCNATHCCNATHTCNATGTGYTGGGGNTGYGARTTYGCNTAYATHACNTTYGCN CAYGTNTGGTCNATHACNCCNTGYATGMGNTCNTAYATGATHCARTGYGGNTGYATGCAR AARTTYTAYGGNACNTGYYTNCARTGYTGYATGCARCCNTGYTTYGARTCNATGGGNTAY ATHYTNAAYAAYATHAARGTNACNAAYGTNAGY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AGYAARTCNGTNTCNGARYTN GAYCARYTNTCNGAYTTYTCNGTNTAYAARGAYTGGMGNCCNCAYTCNAARTCNYTNACN MGNCAYAAR---AGYTGGGGNAGYGAYYTNGAYAARACNMGNAAYACNACNTTYATGTCN GAYGAYACNAAYGTNGAYYTNTCNATGTTYAGYCARTCNGTNGGNAGYCCNMGNAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TCNAAY TGGAAYCARGARACNAARTCNMGNYTNAAYGARAARGTNGCNTCNAAYGTNAAYGAYYTN GGNTCNYTNATGMGNCARGTNATHMGNGGNTCNAARACNAAYGARTTYYTNGCNCARGCN GCNAARAAYTTYGCNTCNCARGARAGYTAYATHCARAAYTCN------------ACNGAR ACNATGAARAARATGGAYATGACNMGNTCNCARYTNGARTTYCAR--------------- ---------------------------------CARTCNTCNATHTCNMGNAGYYTNCAR CAYYTNGAYGARGTNCARGAYCARYTNTCNACNYTNCARCAYCCNTCNAARAARGCNYTN GARTGGTAYGTNAAYAAYATGAARMGNTCNGGNGAYCAYGTNYTNYTNTTYCAYTGYTCN CARYTNCARYTNCAYATHGGNYTNCCNGGNGTNGCNGTNGAYATHGARGCNGTNAGYGAR CARGTNAARAARGCNAARGARGCNGCNGAYGCNATHATHACNGARGCNAAYGCNGTNYTN AGYCAYGAYGAYATHAARGTNTAYAGYGTNATHAARAGYTCNTCNAARCCNCARGAYGCN ATHYTNGARGCNGCNCARGARGARGARGTNGAYCAYATHATHATGGGNACNMGNGAYATG GGNGCNYTNAARMGNGCNTTYGTNGGNAGYGTNAGYACNGCNGTNGTNMGNCAYGCNAAY GTNCCNGTNACNATHTTYAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GAYGAYGAYGAY GAYGGNAAYGAYAARAARAAR------GCNCCNAAYGARYTNYTNATGGARTTYGTNGAY TGYYTNATGAARAARGAYTAYCCNAAYGCNAGYAARYTNTGYAARATGATHYTNYTNTAY GARCCNGARAAYGARGARGCNYTNAARTTYCARCCNYTNATHGARAARAARATHCARYTN GAYGCNGARGCNGARGAYGARGGNAGYAGYGAYGAYGAYGAYGAYGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGYTNGAYAARTAY GAYTGGTAYATHGTNCCNGTNACNAAYCCNGAYGGNTAYGARTAYTCNMGN------ACN AAYGAYMGNYTNTGGMGNAARAAYMGNAAYAAYGGNMGNMGNGCNTGYAARGGNGTNGAY YTNAAYMGNAAYTTYGAYTTYCAYCAYGGNACNACNGGNGTNTCNTTYTAYTCNTGYAGY GAYGTNTAYCCNGGNACNAARGGNTTYTCNGARCCNGARACNGCNAAYATHCARCAYYTN TTYAAYGARYTNAARTCNMGNGTNGTNAGYTAYGTNTCNGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNGTNYTNATHGTNTCNACN AGYGCNGCNTGYMGNCARATGTGYTAYACNTGYCARTAYGTNYTNAAYGGNCCNGGNATH GARTGYGTNACNGCNCCNYTNAAYTGGACNGGNGGNGARCCNMGNATGMGNTGYCCNACN AGYTGYACNATHATHGCNGARTAYGAYGCNGARAGYGGNAAYCCNACNTTYTTYAGYMGN GGNTGYGGNGTNGCNMGNGCNGAYCARAARGAYGAYTGYGTNAAYAAYGGNGCNMGNCAY AGYTGYTTYTAYTCNTGYGAYGAYAARAAY---TAYTGYAAYGAYCARTCNYTNCCNAAR TCNCCNTTYATHGARAARAAYGGNGGNAAYACNGGNGCNTCNAAYGGNAGYCAYGAYYTN GARGARGCNTGYAARTTYGCNGCNGAYGGNATHGGNAARGAYTGGAARACNGTNTAYTTY MGNYTNCCNTTYGAYCCNCCNMGNGAYCCNGCNMGNYTNCARMGNGAYGTNTCNGTNYTN GAYCAYATHGCNTAYMGNGGNGAYGCNCCNCCNGARAARCARGCNYTNAARTGYYTNCAR MGNTGGMGNACNYTNCAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYAARAARAARGAYAARGAYMGNCCNCCNTCNAARATHGTNATHMGNMGNYTN CCNCCNTCNYTNACNCCNGARAAYTTYYTNGARCARGTNTCNCCNYTNCCNGAYCAYGAY TTYTTYTAYTTYGTNMGNGCNGAYACNAGYYTNGGNYTNAAYGCNTTYTGYMGNGCNTAY ATHAAYTTYYTNAAYGCNGARGAYATHTTYATHTTYMGNGAYAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GAYAARATHMGNGGNGGNGGNGARATGTTYAARTTYCCNTGGACNTCNTAY GCNAARGTNCARCARTTYCCNTTYAARTTYTAYTGGAARCAYGGNMGNYTNTTYMGNTAY TTYTTYTAYTCNTCNGCNYTNYTNTTYCCNYTNATGGTNAARYTNACNAARGCNACN--- ---------------------------------GCNCAYYTNCARYTNGGNGGNYTNCCN GTNTTYYTNCCNCCNCAYCCNGCNGCNGAYCARGCNGCNYTNMGNCCNCARTTYCCNACN ATHGTNCCNGTNAGYGGNGCNCCNMGNAAYCCNGAYGARCARCCNMGNYTNACNGCNCAR CCNYTNGGN------ATGCCNATHTCNMGNCARGCNCARCCNTTYATHYTNGCNGCNCCN MGNYTNCCNCCNCCNACNGTNGTNGCNTCNAGYCARGCNAGYATGAAYGGNACNGCNCCN CCNCCNYTNGTNTCNCCNCCNCAYGARGCNGCNGGNYTNGTNTAYAAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------- >californica ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AGYGAYAARCARYTNCCNGCNTAYTGYAAYCCNCCNAAYCCNTGYCCNTTYGGNAAR ACNGCNGARGARAAYTGYGTNGARAAYTTYGARAAYTCNGCNGARAAYAAYAARAARYTN YTNAGYGARCARGARTGYCCNTGYGAYMGNGARCAYATGTTYMGNTGYCCNYTNGGNCAR GARACNGTNTCNTCNAARGGNCAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGNGGNYTN ACNATHYTNTCNATHYTNATHGGNYTNTTYCARACNCCNTTYGCNGCNACNATHGARGAY AARTAYGARCCNATGGTNGCNTTYATHTGYGAYMGNCCNGCNATGCAYMGNGGNGTNAAY GGNTGGGARGCNGAYAARAAYATGGAYTGYCCNTCNAAYYTNCARCARATHYTNGARTAY TGYCARTCNGTNTAYCCNGAYCAYAAYATHACNAAYGTNGTNGARGCNTCNTAYYTNGTN GAYATHCCNGAYTGGCCNATGGGNACNGCNMGNMGNGARCAYCCNCAYMGNGTNMGNCCN TTYMGNTGYYTNGTNGGNGGNTTYCARTCNGAYGCNYTNYTNGTNCCNCARCAYTGYGAR TTYGAYCAYMGNCAYGAYGTNGCNYTNTGYGARAARTTYTCNCAYTGGAAYGARGTNGCN GAYGTNGCNTGYACNAARAARGGNATGCAYYTNGARAGYYTNGGNATGYTNYTNTAYTGY AAR---YTNGGNCAYTTYAGYGGNGTNGARTAYGTNTGYTGYCCNAAYGARACNGARCCN MGNGARCAY------CCNTCNCCNAARGTNGAYGAYAARCCNGAYGCNTGGCCNGARGAY TCNGAYGAYGAYGTNGARGAYGARACNGARGARGAYGARGARGAYTCNGAYGAYGCN--- ---CAYAAYAGYAGYTCNGARGARACNGTNGAYGAYGGN--------------------- ---------------------------------AAYGTNGCNAAYYTNTAYGARGCNTAY YTNMGNAGYAARCARTTYCCNAGYAARTAYAAYAAYGARCAYAARMGNTTYYTNGCNGCN AARMGNCARATGYTNAARGAYCARAARCAYAARGTNGCNCARYTNYTNCARCARTGGCAR AARGCNMGNGAYCAYGTNAARCARGTNAAYCARTCNGAYCCNAARACNGCNGARGCNATG AAYAARGARATHGGNGARMGNTTYCARMGNYTNTAYGCNGCNTAYGARCARGARGAYGCN GCNGARAARCARCARYTNGTNGCNYTNCAYCARCARCAYGTNCARGCNAAYYTNAAYGAR MGNAARMGNGAYGCNATGGARAARTAYATGAARGCNYTNACNAARGGNGAYGTNGAYYTN ATHATHAARTAYYTNCAYTCNTAYATHAARGCNGARGARAARGAYMGNATGCAYACNATH AAYCAYTTYGARCAYATHAARTAYACNAAYGCNMGNGARGCNYTNMGNATHCAYCCNCAY ATHGTNAAYCAYYTNAARYTNTCNGARGARMGNATHGAYCARGCNYTNGGNATGYTNAAY MGNTTYCCNGARATHGARGARAARGTNAARCCNGARATHCARGARTTYYTNAARMGNTTY GCNGCNATHGCNGAYAGYATHMGNAAYGTNGTNYTNCCNGTNCCNGARGTNGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNATHTTYGARCCNCCNMGNGTNATHACNMGNMGNAGYYTNYTNAARTCNGTNTTYATH TAYAARAARCAYCARCAYCARTAYGARACNMGNACNAAYTAYAARGTNTTYGARTTYAAR CAYYTNACNGGNTCNACNGCNAGYACNTTYYTNGARTAYATHCARMGNAAYYTNCCNGAR GGNGTNGCNATGAARGTNACNAARCAYCARYTNCAYCCNTTYCCNGARCAYGTNAARTGY CCNGARACNGARGCNYTNAGYGARAAYGARCCNAGY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGGCARGCNTCNTCNYTN GTNGTNMGNMGNCAYGTNAARTAYTAYAAYTGYTGYATHGARCCNTTYCCNGAYGTNACN TTYGTNGTNCARYTNMGNMGNMGNACNAARTAYTAYTTYATGAAYATHATHGTNCCNTGY ATHATHYTNAGYTTYYTNTGYYTNGCNGGNTTYYTNYTNCCNCCNGARAGYGGNGARAAR ATHACNYTNGGNYTNAGYGTNYTNYTNACNATHACNGTNTTYATGYTNATGGTNGCNGAY AARATGCCNCAYACNTCNGTNCAYGCNATGAAYCCNGARGARAARGCNAARCAYYTNGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARGAYYTNAARATGGGNGCNGCNCAYGARGARAGYGCNCARGAR GGNGAYACNACNGCNCCNCCNCCNAGYGARAARGTNAARGCNCAYTTYGTNGCNYTNGTN AAYTTYAAYGGNTCNYTNTAYGARYTNGAYGGNMGNAARAAYGGNCCNGTNATHCAYGGN CARACNACNGARGAYTCNTTYYTNGARGAYGCNGCNAARGTNGTNCARAARTTYATGGAY MGNGAYCCN--------------------------------------------------- ---------------YTNACNAARGAYGARAARACNGTNAGYGAYTAYATGGTNAARYTN AARAARAAYATGATGGARTCNTGYMGNYTNAAYAARACNGARTAYTAYCCNAGYYTNAGY TTYTTYAARTCNAARCCNYTNATGGARCARTCNAARYTNTTYAARATHTTYMGNAARATG CCNAARGGNGGNGCNYTNCAYYTNCAYGAYATGTCNATHACNAGYYTNGARTGGGTNGTN AARAAYGTNACNTAYMGNGAYAAYYTNTAYATGTGYGTNGAYGCNGGNGGNTAYATGATH TTYMGN---TTYAGYYTNGGNCCNCCNGAYACNTCNTGYAGYTGGAGYACNGTNAARGAR MGNMGNTCNYTNGCNCARAGYATHGAYGAYTTYGAYGARAGYATHMGNAARAAYATHAGY TAYYTNACNYTNGAYCCNYTNGARGCNTAYGCNGAYGGNGAYAARGCNTGGGTNMGNTTY GAYAARTAYTTYGARCARGTNATHGGNATGGTNTTYCAYGCNCCNGTNTTYAARGAYTAY TTYTCNCARGCNYTNAARGARTTYAAYGARGAYAAYGTNCARTAYATHGARYTNMGNGGN CARATGTTYGAYACNTTYGARYTNAAYGGNGAYACNCAYGAYGCNGARTAYGGNYTNAAY ATGTAYAARACNGCNATHGARGAYTTYAARAARAARAAYCCNGAYTTYATHGAYGCNAAR TTYATHATGTCNGGNYTNMGNTTYAARCCNGTNAARGAYATHAARGGNGARGTNCARACN GCNATGAARYTNTAYCARAARTAYCCNGGNYTNTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TCNCARCARGARYTNTCNTCNCARTCNGGNGCNTCN------TCN MGNACNAARMGNCARAGYTAYTCNATGYTNMGNYTNGGNMGNGGNYTNCARATGYTNMGN YTNGGNAARMGNGGNAGYCCNGTNGAYGCNGAYTCNTCNCCNYTNYTNGAY--------- ---------AAYGCNTAYTAYAGYAGYTTYCCNGAYMGNYTNGARGAYTTYCCNAGYTCN ---------------------------------------------MGNYTNMGNMGNTCN ACNATGAAYCCNGARGTNGAYGCNGARCCNGCNGTNGARCCN------------------ ---GGNGTNGTNGAYGGNGARACNGGNAGYGARGTNGAYGGNTAYTAY------------ ------GTNYTNCCNGAYGAYTTYYTNGARGARYTNYTNGARGARGARGGNYTNACNGAR GARCARAARMGNTCNYTNTCNATGYTNMGNYTNGGNAARMGNGCN--------------- ------------GAYTTYATHCCNGTNGAYGARGTNGAYGGNCCNGARGCNGAR------ ---------------------------AARMGNAAYYTNCARATGYTNMGNYTNGGNAAR MGNAAYYTNAAYATGYTNMGNYTNGGNAARMGNAAYYTNAAYATGYTNMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GARGGNMGNAAYYTNACNGTNATHGAR ATHACNGARGAYCCNGGNATHCAYAARCCNGGNAARCCNGARTTYAARTAYGTNGGNAAY ATGCAYGGNAAYGARGTNACNGGNMGNGARATGYTNYTNTAYYTNATGYTNGTNATGTGY GARGARTAYAARAARGGNGAYGAYYTNGTNATGTTYATHYTNAARGARACNMGNGTNCAY ATHATGCCNTCNATGAAYCCNGAYGGNTAYGARGARGCNTAYMGNGARATGAARGARAAR GGNAARGTNGGNTGGYTNACNGGNMGNTCNAAYGCNAARAARGTNGAYYTNAAYMGNAAY TTYCCNGAYYTNAAYGCNAARATHTAYGAYAAYGARAARCAYCAYMGNGGNMGNAAYAAY CAYYTNYTNAARATHGARAARGCNTTYGCNACNGAYAARAGYYTNCARCCNGARACNMGN TCNGTNATGMGNTGGYTNGCNGARAAYGGNTTYGTNYTNTCNNNNAAYYTNCAYGGNGGN GAYYTNGTNGCNAAYTAYCCNTAYGAYGARACNMGNTCNGGNAARCCNCARGARTAYACN GCNTGYCCNGAYGAYAAYACNTTYGTNTAYYTNGCNAARTCNTAYGCNTAYYTNCAYMGN ACNATGGCNGAYCCNMGNMGNGARCCNTGYGAYAARGARGGNAAYAAYAAYCCNATHACN AAYGGNGGNAARTGGTAYTCNGTNGCNAARGGNATGCARGAYTAYAAYTAYYTNAAYACN AAYTGYTTYGARATHACNYTNGARYTNGGNTGYAAYAARTTYCCNGARGARTCNCARYTN GARAARYTNTGGTCNGAYAAYGCNGARGCNYTNTTYAAYTAYATGYTNCARACNCAYATH GGNGTNAARGGNTTYGTNAARAAYTCNAAYGGNGARCCNATHGCNGAYGCNGARATHAAR GTNGTNAAYYTNGCNTCNGGNYTNCCNATHGAYCAYGAYATHYTNGCNYTNGAYGAYGGN GAYTAYTAYMGNYTNYTNGCNGAYGGNTTYTAYCAYATHGCNGTNAAYGCNCCNGARTAY CAYACNTCNGGNMGNTGYATHACNATHAARAAYACNATHMGNGTNGGNGCNTCNCCNTCN GARGTNACNACNGCNCCNCARGTNAAYTTYACNYTNATHCCNGCNTCNGARCCNGARCAR GAYGAYTCNGARGARATGMGNACNTGYGARTTYYTNTGG--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYGAYMGNTAYAARCAYATHCAYAAYGCN ATGTAYTAYGAYATGTGGATGACNACNMGNAARGCNYTNATHYTNATHGCNTCNGTNTGG TTYYTNTCNGCNYTNATHTCNTTYYTNCCNATHCAYYTNMGNTGGCCNATHCAYTGYTGG GTNCCNGCNYTNTAYAARAARAARTAYTAYCARAARTAYTCNGAYAGYATHTGYTGGATH AARCCNATGTAYAAYGTNCCNATGGARGAYGCNATHCCNTTYGCNCCNGCNGAYMGNTGG TTYAAYGARGTNAGYTAYTAYMGNTGGGTNTTYGCNGTNTTYYTNATHCARGCNYTNYTN TTYAARYTNCCNAAYATHGTNTGGGCNCARYTNMGNCARTAYTCNGGNYTNAAYYTNACN AARATHGTNGCNATGGTNTGGGAYACNTCNATGATGACNCARGAYGAYMGNGAYAARAAR ATGAARAAYATHGTNATHTTYATHGAYMGNTGGYTNAARACNTAYTCNCARTAYMGNTTY AGYGCNATHACNMGNTTYMGNGAYAARTTYTCNAGYTTYTGYTTYTGYTTYGGNAARMGN GCNGGNAAYTAYYTNAGYGGNYTNTAYATGTTYACNAARYTNYTNTAYYTNGCNAAYAAY ATHGGNCARTTYTTYYTNYTNAGYGCNTTYYTNGAYATGGAYTTYTGGAGYTTYGGNGCN GAYGCNATHAARAARTGGAAYGAYAARGGNAARTGGCARGAYYTNTAYMGNTTYCCNMGN ATHGGNATGTGYGAYTAYGARGTNMGNCARYTNCARAAYATHCARMGNATHTCNACNCAR TGYGTNYTNTCNATHAAYYTNTTYYTNGARAARATGTAYYTNATHYTNTGGTTYTGGYTN GTNGTNYTNYTNGTNTTYAAYGTNATHAAYYTNTTYTCNTGGGTNMGNCAYGGNYTNACN CCNMGNTCNAGYGARAAYTTYATHMGNAARTAYYTNYTNTTYYTNGGNATHGAYTCNAAR AARGARACNAARYTNTTYGTNAARTTYGTNCAYAAYTAYYTNMGNACNGAYGGNATHTTY ATGATHMGNATHGTNGCNAGYAAYACNAGYGARATHYTNACNACNGAYYTNATGAARCAR YTNTGGAARGTNTTYAARGARCARCAYMGNAARGAYGAYYTNGAYAAYAAYAAYCCNAAY GGNAAYCAYCCNYTNGCNCCNCAYCARCCNCCNTCNCCNGARGGNCAYYTNTCNACNCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYGARAAYAARGTNAAYCCNTCNATHYTNGTN CARGAY------GAY------GARGARCARACNGTNGARAARMGNMGNTAYATGGGNYTN TGYTAYCAYCARAARGCNAAYACNTTYGTNCCNTTYCCNTGYYTNMGNAGYGGNMGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNATGTTYATGGTNGTNYTNACNGGNTCNAGYTGYGCNGTN TTYTAYACNAARGAYCCNGARGTNGAYTAYCCNMGNATHGGNMGNMGNAGYTTYTAYACN ACNAGYGARGGNAAYCAYTAYCCNMGNATHGGNMGNMGNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CCNGTNAAYGTNACNGTNGCNYTNACNYTNGTNGAYATHYTNAARGTNGAYCARGARACN GGNCARGTNGAYATHGTNGCNTGGGTNNNNAAYNNNTGGAARAAY---NNNNNNTGGGAN CCNGCNNNNTTYGGNAAYGTNNNNAANYTNGCNATHCCNTCNAARYTNYTNTGGGTNCCN GAYATHTAYGCNTAYAAYGGN---ATHTCNAARATGGARNNNYTNTCNCCNGANNNNYTN NNNATHNNNCAYACNGGNNNNGTNNNNTAYGTNCCNAGYATHMGNATNAGYTTYYTNTGY GAYYTNAARMGNCARGAYATHTCNACNAAYGCNACNTGYGARYTNAARYTNGGNTCNTGG GTNTAYAGYGGNNNNNNNATGNNNYTNATHAAYCCNAGY------NNNGAYYTNNNNNNN TAYTTYTCNGGNTCNAARTAYNNNGTNYTNGGNNNNNNNGCNAARAARGARNNNNNNNNN TAYNNNTGYTGYCCNGARCCNNNNATHNNNYTNAARTTYGTNNNNTCNTTYAARGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNGAYATGACNGCNAAYYTNGTNGAYACNTTYAARGAYTAYTTYMGNATHGCNATHCCN YTNGAYCARCARGAYATHGTNGCNGTNCCNAGYGAYAARGTNAAYGAYATGGARAAYTGG GGNYTNATG------------ACNGCNATHGCNGAYGAYTAYYTNCARTAYCCNGAYGCN TCNGCNGARATGYTNAARYTNYTNYTNGCNAARAARATGGCNMGNCARTGGTTYGGNAAY YTNGTNACNACNAARCAYTGGAAYGGNYTNTGGYTNCAYGARGGNATHGCNTCNTTYATG TCNTTYACNGGNYTNTCNGCNGTNGARAARGAY---------------AARCARACNATG GAYGAYYTNCARAAYACNYTNTAYCARGAYAGYTTYGAYAGYCCNTTYTCNGTNYTNGAY AARTCNGAYAAYGAYACNYTNGTNCARGARAAYTTYAGYCARTTYTCNTTYGAYAARTGY GCNTGYATHGCNAARATGATGCARAGYGTNGTNGGNMGNACNMGNTTYMGNAARGGNYTN ACNTAYTAYYTNACNCAYCAYGCNTAYGGNAAYGCNGARCCNGARGAYTTYTGGAAYGCN YTNCARCARMGNYTNCCNGCNGGNATHACNGTNACNAARATGATGAARTCNTGGACNAAR CARGARGGNTAYCCNGTNATHACNATHTCNMGNAARGGNGAYCARYTNCAYATHACNCAR GARMGNTTYYTNATGAAYGGNACNCARGAY---GAYGARGARNNNNNNNNNCCNTTYNNN NNNNNNTGGNNNGTNCCNTTYNNNNNNATNACNTCNNNNNNNCCNNNNNNNNNNNNNATG NNNTGGNNNNNNNNNNNNNNNGCNNNNNNNNNNNNNNNNNNNNNNNNN---TGGNNNAAR GGNAAYNNNNNNNNNNNNGGNTTYNNNMGNGTNAAYTAYGAYAANGANGGNTGGNNNNNN ATHATHNNNCARYTNNNNGANAAYCAYNNNGTNTTYAGYGTNNNNGAYMGNGTNNNNYTN ATHGAYGAYNNNTTYNNNYTNGCNMGNNNNNNNYTNNNNGAYTAYNNNNNNGCNYTNGAN YTNNNNNNNTAYYTNNNNNNNGARACNAAYNNNNNNNNNTGGNNNNNNNNNNNNNNNCAY NNNNNNTTYNNNCARNNNATGYTNTAYNNNNNNNNNAGYNNNGAYNNNYTNNNNNNNTAY ATNNNNNNNNNNGCNATNCCNNNNNNNNNNNNNNNNNNNNNNATNGANCARGANAAYNNN NNNNNNNNNNNNNNNNNNNNNYTNATGGTNTCNYTNNNNGTNNNNYTNNNNTAYGARCCN TTYNNNNNNNNNGCNNNNNNNYTNTTYNNNNNNTGGNNNNNNTCNYTNACNAAYCCNAGY YTNAAYAAYCAYATHYTNATHYTNTCNGCNGGNATHCARACNGGNGAYGCNTTYGAYTGG CAYAARYTNTTYGARAGYTAYAARTCNAGYYTNGARCCNTCNGARCARAAYATGYTNYTN TCNGGNYTNGCNTCNACNACNATHGAYMGNAAYYTNCARATHYTNYTNGARCAYAGYTTY GARAAYGTNGGNACNAARCCNCAYCARYTNCCNGCNGTNATHAARGARGTNTCNAARAAY MGNGAYGGNYTNYTNYTNGCNTGGAARTTYYTNMGNGAYMGNTAYGAYGTNYTNTCNCAR MGNTAYAAYGARGAYCCNACNYTNGTNAARGAYATHATHTCNAAR------------TTY CARATHGARTTYGARYTNCAYGARGTNCARAAYTTYTTYAAYAAYAARAARATHGGNATH GCNAARYTNAARYTNCARTCNGCNGTNGARGAYYTNAARTCNMGNATHCARTGGCCNCAR ATHAAYCARCAYATHGTNGARGCNTGGYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------MGNGTNATHACNMGNTCNTCNATHACNAAYAAYGCNAARGCNYTN CAYCARAGYGARAARCCNTGGAAR---------CCNGCNAGYAAYGCNGCNGCNACNGAY AARACNAARYTNGARCCNGARGTNYTNTTYATHATGAAYMGNYTNACNCCNACNAAYTTY GARMGNYTNGCNYTNGARATGAARAARYTNAAYATHAARACNTAYGARGAYYTNCARCAY YTNGTNAAYATHTTYTTYGARAARGTNACNATGGARACNAARTTYGTNCARGCNTAYGCN CARYTNTGYAARGTNATGTCNGGNYTNAARGTNCCNCCNCCN------CCNAAYATHAAR GARAAYCARGCNACNTTYMGNGTNGTNATGYTNACNAARTGYCARCARGARTTYGARGCN GAYAARAGYATHATHTTYGARGAYCCNGARGARAARAARAARAARYTNATHTCNGARYTN CCNGAYACNCCN---GAYMGNGCNGARACNATHGARAAYACNYTNTAYMGNATGAARYTN AARMGNATGAARTTYTAYGGNAAYATHMGNTTYATHGGNGARYTNTTYAARYTNGGNATG YTNACNGARAAYATHATGCAYGAYTGYATHTAYMGNYTNYTNAARGCNMGNGAYGAYGAY TCNYTNYTNTCNYTNTGYCARYTNYTNACNACNGTNGGNCARGCNYTNGAYACNGAYAAR GCNAARCCNMGNATGGAYCARTAYTTYACNCARATGTCNAARATHGCNGAYGARMGNAAR TCNMGNATHAARTTYTCNYTNAARGAYACNGTNGARYTNMGNCARAAYAAYTGGATHCCN MGNAARGARCCNACNTGGCCNAARAARATHGAYGAYYTNCAYAARGAYTTYGCNGARGAR CARGCNMGNAAYCARNNNYTNAGYTCNCARCCNYTNCCNCCNMGNAAYGAY---CCNCAR CCNGGNAGYMGNMGNGGNAGYMGNCARMGNCARGAYGARAAYAARCCNACNGAYGAYGGN TGGAAYACNGTNGCNTCN---MGNTCNATGAAR---ATHGAYGCNTCNAARATGAARYTN TCNAAR---AGYGTNGTNGAYGARAAYATHCARYTNGGNCCNGGNGGNGGNATGAAYMGN ---CCNATGTGGGGNMGNGGNAGYCAYGGNGGNGCNCARGCNTCNCARGAYGARMGNCAR CCNGCNCCNGCN---AAYMGNTTYTCNGCNYTNTCNAARGARGARGARMGNMGNCCNTTY CARAARTCNCCNTCN---------GAYGGNCCNAGYMGNAGYATGMGNCARGGNTCNACN GTNGGNCAYGGNMGNGGNAAR---ATHTCNMGNTCNAGYGCNGARGGNGARMGNMGNGAY GCNATHAAYAGYGCNMGNTCNATGATGGGNGGNMGNTCNCARAAYTCNAGYMGNGAYAAY AGYTGGAAYMGNGAYGAY---MGNMGNATGACNGGNCCNMGNAGYTCNAARGARGGNGAY ---ATHATGACNMGNAGYGAYACNACNYTNMGNCCNAGYGARGARTTYMGNAGYCCNYTN CCNCCNCCNAAYGGNAARAARMGNATGAARGARGAYGARATHGARYTNAARTCNCARAAY ATHATGGARGARTAYYTNAAYGTNAARATHYTNGAYGARGCNAARYTNTGYGTNAARGAR YTNGAYGGNGARCCNTTYATHCAYYTNTTYGTNACNTCNAGYATHAAYYTNGTNYTNGAR AARTCNGARCARGCNMGNGTNYTNGCNGGNCARTTYTTYCAYGARYTNATNCARAGYAAR ATHATGCCNYTNGARACNTAYTTYAARGGNYTNATHGARGTNYTNAARTTYGCNGARGAY ATGGTNATHGAYATHCCNAARATHTGGGCNTAYATHGCNCARATGATHACNCCNYTNATG ATHGGNCARAGYYTNGARYTNTCNCARYTNAARTCNGTNTTYAARCCNCAYYTNCARGAY AARTGYTGYGCNYTNYTNYTNGCNCARATHYTNCARCARGCNGCNGCNAARTCNGGNGAY GARGCNGTNTCNATGYTNTGGCARAAYAGYGGNYTNGARTGGTCNATGTTYATHCARCCN GAYGAYGTNGGNAARTTYGTNCARAAYGARAARGTNGARTTYTCNGTNGCNCCNGTN--- ------------TCNGGNGTNCCNNNNNNNNNNNNNCCNGCNTCNYTNACNTTYNNNGAY GGNATHAARACNYTNATHCAYGARAARNNNNNNGCNNNNNNNGTNACNGCNTAYATHGAN AANAAYTTYNNNGGNNNNAARNNNGAYAARNNNTTYATHMGNGARYTNACNNNNNNNYTN GTNNNNGCNTCNYTNNNN---------GANNNNYTNAANGTNNNNGANAAYNNNTTYAAR GARTGYNNNNNNGTNYTNCARNNNNNNATHGGNNNNNNNNNN---NNNYTNGCNYTNCAR GTNYTNTAYGCNATHCARGCNYTNATGTCNAARYTNGARCAYCCNCCNGGNGTNATHNNN AARYTNTTYAAYAGYYTNTAYGANAAYGAYGTNNNNNNNGARGARACNTTYCAYCARTGG AAYACNAGYACNGAYCCNAAYGARNNNGARGGNMGNGGNGTNTGYNNNYTNCARGTNNNN CARTTYATHACNTGGYTNCARGARAAYGANGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ACN TCNGTNGARACNYTNTTYGAYCAYGAYTAYACNGCNAARTGYAARAARGCNACNGCN--- ------GTNAAYAAYAGYACNTCNYTNGTNYTNGARGTNTCNTCN---ACNACNGAYYTN GARGARGCNTGYTCNAGYAARAGYCARGARGAYAARCARACNATGMGNMGNGTNAARAAY AAYATHGCNTCNAARMGNTCNMGNGARCARMGNAARCARAARTTYGTNAAYATGGAYGAY GARGCNGAYATHYTNATHGTNGARAAYGAYAARYTNMGNGCNAARATHATHGARYTNGAR AARYTNGCNAARGARATGAARGARGTNYTNATHGCNAARATGGCNGGN------AARCAR MGNGGNTCNACNCCNYTNAAYGCNYTNYTNCCNMGNTTYTTYAARAAYCAYGARTGYTTY YTNTGYCCNGGNAAYGCNAAYATHACNCARCCNAAYGAYTCNGGNMGNACNYTNGTNATH GAYTTYYTNGCNCCNCCNCARCARGARGGNTTYTAYCCNGCNGCNGCNGCNTTYATGAAY GARTTYAARTCNCARAARGTNMGNCCNCAYTGGGCNAARMGNCAYGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GAYAGYTCNGAY GCNGCNGAYTCNAARGTNTCNTCNACNTTYGGNTCNAAYCAYACNCARAAYTCN------ ---------------GARACNGGNGAYGGNCAYCARGTNGTNAGYAGYTCN------AAY GTNGAYTCNTAYTCNAGYTCNCARGTNCCNAARYTNACNAGYNNNNNNCCNNNNNNNNNN NNNNNN------NNNGGNTCNGCNCAYAAYACNGGNATGTAYTCNAAYCCNTTYGTNCCN AARGCNCCNYTNAARACNGAYGTNGTNTCNACNGGNCARCCNAAYTCNGAYGAR---AAR GARAGYYTNATHGCNCCNAGYMGNYTNAAYGCNGCNGTNAAYMGNGARACNTCNGARGCN GAR---GARGAYAARMGNAARTAYYTNAARCCNTCNGTNYTNGCNGCNCCNAARTTYGGN GGNTCNGGNTTYGGNAGYGCN---------------------AGYCCNTCNTAYAGYTCN GTNAAYTCNTTYCARATHGCNCCNTCNGTNTTYTCNGGNCARYTNGAYACNTCN---GGN AGYCCNAARGCNCCNYTNYTNAARCCNGCNAARYTNCCNGAYCCNACNAARACNTCNGAR GCNAARGCNGAYTCNGCNAGYGAYGTNGAY---ACNATH---------CCNGAYAARGAY ACNGARGCNTCNGCNGTNAGYGARMGNYTNGGNGGNGCNGAY---------GGNGGNAAY GARGTNACNTCNTCNTCNTCNTCNTCNGCNTCNGCNACNCCNACNAGY------AAYGCN GAYGCNGAYGGNGCNAARGCNGCNGARGCNACNCCNTAYAAYCARGAYATHGTNCCNGAY ATHAGYAARAAYAAYMGNYTNAARGAYTCNTCNGGNGTNTCNAGYAGYTCNCARTCNTTY GTNTTYGGNAGYAAYYTNTCNCARMGNGTNACNGGNGTNTCNTCNCCNTCNCAR------ ---------GGNGCNACNTCNGGNTTYGTNTTYGGNGARTCNYTNTCNTCNMGNATHCAR CCNGARACNAAYGGNTCNAGYCARCARCCNGCNAARGAYGAYAGYGAYTCNGARTCNGGN ---AARGTNAAYCARACNYTNGARGARTCNGCNMGNGARTAYCARGCNAARCAYGARAAY AARACNGARYTNAARGARGTNGARMGNATHACNGGNGARGARGARGARTCNAAYGTNYTN CARGCNAAYGCNAARYTNTTY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TAYMGNTGYATHGARTGYGGNGCNGGNGTNAARAAYYTNTAY ACNAAYTAYAGYAGYTCNCARATHAARGTNYTNCAYTGYGARTCNTGYCARAGYGTNGCN GAYAARTAYATHGARTAYGAYCCNATHATHGTNYTNYTNGAYACNYTNYTNYTNCARMGN CCNGCNTAYMGNCAYYTNATHTTYAAYACNACNTTYAARCCNYTNTGGAARTAYGTNTCN YTNYTNTGYATHTGYGAYGCNTTYACNAARYTNATHCARGARMGNGCNAARATHGGNGAY YTNTTYGAYCCNTCNYTNAGYTCNGGNTCNAARTTYGAYATGGTNCAYYTNTAYGTNGTN AAYTAYYTNYTNTCNGCNTCNGARATHGCNTCNTTYYTNGTNTGYGTNTCNTTYATHYTN GTNYTNCAYAAYTTYATHGTNTAYGGNAGYATGAARTCNYTNAGYTGYTTYGTNATHATH AARGCNATHATGATGGGNAAYYTNGGNMGNATHTCNGCNATHCCNGCNTTYYTNTGGGGN CARTCNTAYAGYTTYTTYTTYYTNMGNATHTGYCARATGTAYGTNGGNTTYACNTCNTTY CARTCNYTNAGYGTNATHGTN---CCNGGNMGNTTYAAYATHATHGTNTCNGTNACNGCN ATHTGYTTYGGNATGYTNGTNAARGTNATGYTNTCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNATHAARCCNATGAGYATHAARGTNTAYGAYTAYGAYMGNGCNTGGAAYGAYGAY CCNATGGGNGGNGCNGAYATHGAYYTNGCNACNYTNGARGTNGAYAARGARACNGARATG AARYTNATGYTNAGYGARMGNGGNAARACNGARTAYATGGGNTAYYTNYTNYTNGCNTGY ACNYTNGTNCCNAARACNGARGARGAYAARGAYCARYTNTTYMGNMGNTCNGTNMGNTCN GTNGAYTCNACNAARAARATGAARATGCARACNTGGACNGGNATGGTNAAYATHGTNYTN GTNGARGGNGCNMGNYTNGTNCCNATGGAYGAYAAYGGNYTNAGYGAYCCNTAYGTNAAR TTYMGNYTNGGNACNGARAARTAYMGNAGYAARTTYAARACNAARACNYTNAAYCCNMGN TGGATHGARCARTTYGAYYTNMGNYTNTAYGAYGARCARACNAAYCARYTNGARYTNTCN GTNTTYGAYCAYGAYACN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGGNGTNTGYCARAARGARATHAARATHGCNAARGAYYTNAGYGGNCAYAARAAYATH ATHMGNTAYATHGARTCNAGYATHACNGTNACNCARAAYMGNGTNTAYGARGTNYTNATH YTNATGCARTAYTGYMGNGGNTCNGTNATHCARGCNATGAAYGAYMGNATHAAYTCNGGN TTYTCNGARCARGARATHYTNAARATHTTYTGYGAYGTNTGYGARGCNGTNTCNMGNYTN ---------------------------------------TTYAARCARMGNGCNGTNATH GARTTYATHACNGCNGARGGNTGYTCNGTNGCNAAYATHNNNAARMGNATGAARACNGTN TAYGGNAAYGAYTGYGTNGAYGTNAGYACNATHMGNTGGTGGGCNAARTCNYTNCAYGGN AARGAYYTNAGYAARACNTCNYTNCAYGAYCAYGCNMGNTCNGGNMGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHATG MGNAARGCNGGNCARNNNMGNNNNGAYCARYTNTCNGCNYTNGGNATHGCNMGNATGACN CARCARYTNGGNAGYGAYYTNACNATHYTNGGNACNMGNGARTAYYTNTAYTAYAARAGY AAYGTNGCNMGNAAYTGYGCNGGNAARGCNGTNGARATHYTNCARGARYTNACNACNAAR CARGTNTTYAARCCNTGGGARGTNGCNGAYGTNCARTCNGAYCCNAAYAAYATHGCNYTN GAYYTNGCNGTNYTNAARAAYCARCCNCAYATHMGNGCNATGGARTTYGTNCAYGARGCN GCNTTYMGNGAYACNYTNGGNMGNTCNYTNTAYGCNCCNCCNCAYACNGTNGGNAGYTTY AGYCCNGARCARYTNAAYCAYTTYACNAARACNTAYTTYAGYGCNGGNMGNYTNGCNYTN ATHGGNGTNGGNATHGAYCCNGARGARYTNGARGARYTNGGNTCNATGTTYCARCCNTTY GCNTCNGCNGGNGTNCCNACNGARAARGCNGCNTAYCAR---GGNGGNGARATHMGNGAR AAYYTNGGNGGNGAYYTNGCNTTYGTNTCNGTNGCNTTYGARGGNCCNAGYYTNTCNAGY AARGAYYTNYTNCCNTCNGARGTNYTNAARCAYATHYTNGGNACNGGNCCNTAYGTNAAR TAYAGY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GGNTCNGGNTCNGARACNACNCCNGCNGARTCNTCNGAYACNGCN GARACNGGNGCNGCNACNAGYGTNGAYGAYGCNACNACNGARGCNGGNGARACNGCNGCN CCNAAYGAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNAAYTCNTTYGAYCCNGAYTCNAGYGTNYTNTCNMGNTTYATHTGGGAYGTNGTN YTNYTNYTNGCNTTYYTNGCNCARCAYAGYYTNATGGCNTCNCCNCAYTTYAARTCNGCN ATGMGNCARTAYYTNGGNATHAGYGTNACNGARMGNYTNGTNTAYACNYTNGCNTCNTGY GTNGCNYTNTTYTCNYTNGTNYTNTAYTGGCARTCNATHCCNGARTGYTAYYTNTGGTAY ATHTAYACNCCNCCNMGNCCNYTNGTNTGGTGYATHTTYTTYYTNYTNCAYGTNGTNTGY TGGYTNACNYTNGGNYTNGARGCNGCNYTNATGGAYYTNACNGARATGGTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ACNAARGTN AARATHGAYGTNACNATHACNGAYYTNTCNATHTCNCARGAYGAYYTNCARATGAAYACN ACNYTNTTYGTNACNACNATHTCNGGNAAYAAYTGGTGYYTNYTNYTNGARACNMGNACN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AAYGARATGGARATGGARACNTAY GAYTGYGTNMGNMGNGCNTCNTAYAAYYTNMGNMGNATGAGYCAYAAYMGNGARATHCCN YTNGCNGGNGGNMGNGAYMGN---GCNATGACNATGGAYCAYTCNTAYMGNMGNCAYMGN MGNGGNMGNAGYGCNATHCAYTCNGCNCCNAGYACNYTNCARMGNCAYTAYMGNAAYCAR YTNCCNCAYMGNGAYGARAARYTNGAY--------------------------------- ---------CCNCCNCCNCCNCCNGCNTAYAGYATGTAYTCNGAYGAYGTNTTYYTNGGN CCNGARGAYATG---------------CARGTNAGYTTYCAYTCNGARAGYAAYGCNAAY AAYAAYGAYAAYAGYGCNCARCCNYTNYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ACNGTNCAYAGYGTNATHAAYACNTCN CCNCCNAARYTNYTNAARGARGTNGTNYTNATHGAYGAYGGNAGYGAYTAYGAYTTYYTN AAYAARAARYTNGARAAYTAYATHAARCARTTYAAYGGNYTNGTNAARYTNTTYMGNAAY CCNGARMGNTTYGGNYTNATHACNGCNMGNACNAARGGNGCNGARCAYTCNACNGGNGAY GTNATHGTNTTYYTNGAYGCNCAYTGYGARTGYAAYAARAAYTGGYTNCCNCCNYTNYTN GCNMGNATHAARTAYGAYMGNACNATHYTNGCNGTNCCNATHGTNGAYAGYATHAAYTGG AAYAAYTTYGGNTAYCAYGCNACNTAYGAYCAYCAYYTNCAYMGNGGNATHTTYGARTGG GGNTTYYTNTAYAARGARGGNYTNGTNCCNGAYAARGTNYTNAARGCNMGNGARCAYCCN AGYGARCCNTAYGCNTCNCCNACNCAYGCNGGNGGNYTNYTNGCNATGGAYMGNAAYTAY TTYTTYGARYTNGGNGGNTAYGAYCCNGGNYTNAARATHTGGGGNGGNGARAAYTAYGAR YTNGCNTTYAARGTNTGGATGTGYGGNGGNAGYTCNGARTGGGTNCCNTGYTCNCAYGTN GGNCAYATHTAYMGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARTAYYTN GAYTCNYTNMGNCARAARATHTCNAGYYTNGARAGYGARAARGTNGAYYTNAGYGARCAR ATHAARGARGTNAARGARGAYYTNATHATHTCNGARGARAARMGNTCNCARGAYAARGCN ATGATGGAYTCNYTNAARACNGARYTNYTNYTNTCNAAYACNAAYGTNAARMGNCARGAR AARACNYTNACNYTNYTNGCNAARACNAGYGARGCNGCNTTYGARGARCAYGAYAARYTN CARGARAAYTTYGARAARGARATHCARACNMGNTGYGCNGCNGARAARTTYGCNGARAAR ATGTTYAARGGNCARGTNYTNGCNAAYMGNCARAGYGCNATGYTNYTNAARGAYATHGGN CCNAAYCARAARYTNATGGARGCNATGYTNGARATHCARAARYTNAAYGARGAYGCNATH AARAARAAYGCNGARTAYAARGAYACNACNACNAAYYTNGARAARGARYTNGARTCNTGY AARMGNGAYGTNTTYGTNTGYAARATGGARAARGARAARATGGARYTNGARGAYCARCAY GARGCNGTNATGAARAAYYTNTCNTTYGCNGARGAYGARATHAARYTNYTNAARAARGAR AAYACNTCNYTNYTNGGNAARTAYGCNGARYTNGARAARAARATGGARAAYGCNACNMGN ATHCCNCCNCCNCCNCCNCCNCCNCCNYTNCCNCCNATHAGYGCNCCNAARMGN------ ATHATGGAYATHYTNGGNGGNMGNMGNAARAARMGNGARCARACNGARAARCAYYTNAAR GGNGCNGGNGCNAAYGTNAAYACNGAYTAYTCNAARGCNGTNGAYGARATGATGGTNMGN ATHAARTCNGGNAARTCNGGNYTNMGNTCNATH------------------ACNACNAAY TCNYTNCCNAARGARGARGARGGNAARGCNATGAARGARYTNCARGGNYTNYTNACNAAR ATGAARAARTCNMGNAGYGAYGARGAYYTNYTNGGN---GAYGAYGTNTCNAGYYTNGAY AARACNTCNGARYTNGGNCARATHTTYCARMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNGAYMGNGARGAYCCNMGNAGYGARMGN GAYMGNGAYMGNGAYMGNGAYMGNGAYMGNGAYMGNGAYMGNMGNAARATHGGNAGYGGN MGNATHCARATHGAYMGNGAYGGNAGYMGNGAYTAYACNAAYYTNMGNGAYMGNTAYGGN GAY---------MGNGAYMGNGAYMGNGARCAYCCNTGGAAYMGNGAYMGNYTN------ ------GAYMGNGARTGG------------------GARMGNGAYGAYTGGGARMGNGAY AARGAYMGNMGNTTYGAYMGNMGNYTNGARMGNTTYMGNMGN---TCNGAYAGYTCNTTY TCNGAYMGNGAYMGNMGNGARMGNGAYTTYMGNGAYMGNGAYTTYGAYMGNTCNGAYMGN MGNMGNTAYMGNCARGAYGARAARCARCCNGARTGGTTYACNGGNGGNCCNACNAGYCAR AAYGAYACNATHGARYTNMGNGGNTTYGARAARGARNNNGAYCARGARAAYMGNAGYGAY AARCCNGTNAARGAYATHAAYAARGARGCNGTNAARMGNCAYGGNAARGGNTCNGGNGAR AARTCNGARGAYTTYGTNAARACNTCNGAYGGNGGNACNAAR---------GGNTCNCAR MGNAGYACNCCNYTNGARGAYAAYGTNTTYGCNGCNCCN---------------CCNGGN CARMGNGTNTCNAAYGCNGGNGTNAAYAARTTYGAYTTYGAYGARATHYTNAARGCNGAY YTNCCNYTNGARGARGAYAGYGARMGNCARAGYAGYMGNTTYTCNMGNTTYTTYGARACN GGNAARTCNTTYAAYTCNCCNATGCCNGARATHYTNATGCCNCAYGGNYTNYTNGARGAY TCNAAYTCNAGYCCN---------------TAYYTNCARMGNTGYTCNCCNCAYTCNGCN ACNATGTCNGTNCCNAAYTCNGCNGGNGAYAAYAAYGCNCAYYTNCCNCCNTCNGTNACN GCNYTNTTYAAYAGYGCNGCNGCNGCN---TCNACNAAYTCNGGNATHTCNAGYAAYGGN ACNTTYAGYACNCARGAYGCNGARGCNCARYTNAARGCNATGYTNYTNGGNGGNCCNAAR GAYTCNGCNTCNTCNAGYGGNACNGCNTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GTNTCNGCNAARGGNGGNCAYGARAGYTCNCARGCN TCNACNYTNTCNTCNGARMGNAGYGARGARCCNGARGCNTCNTCNYTNYTNAGYATGGGN TCNMGNAGYAGYTCNGTNATHTCNAAYYTNAGYMGNACNTAYCCNGARYTNTCNTGYCAY ACNGAYAGYGGNTCNCCNGTNGGNGTNYTNTCNGCNTCNCCNTAYGARGGNMGNAARCAR YTNMGNCCNATGTCNYTNCCNAGYATGATHGGNCAYYTNGCNTCNACNAAYACNTCNTCN ACNGTNCARTCNGTNGARAAYAGYMGNTGGACNGAYAGYTCNMGNAAYAGYTAYYTNCCN GARACNATHTTYYTNGARACNTCNACNTGYYTNTTYTCNCCNTTYAAYATGCAYAGYGTN CARGTNTTYCCNGGNGTNACNYTNTTYYTNYTNTCNAARGCNCCNTTYCAYAGYYTNGCN GAYTCNYTNTAYCARGTNATHCAYAAYGTNCARGAYYTNATHTAYGGNMGNMGNTCNAAR YTNCCNMGNTCNMGNAGYYTNCAYGTNTAYGARATHATHAAYTCNYTNYTNGCNAARYTN CAYAAYACNYTNMGNMGNTAYAARGGNMGNGTNMGNAGYYTNAGYCAYGAYATHCAYTCN MGNTGGGARAARGARGAYGTNAARTAYAARYTNYTNGARTAYYTNGARAARGAYGCNAAR TGYCCNATHCCNCCNGARYTNGARTCNCCNYTNYTNGARATGTAYAARAARATGAARGAR YTNTTYTCNTTYYTNTAYYTNTCNACNYTNCCNCCNAAYCCNYTNYTNYTNGARTCNGTN TCNCARYTNMGNGTNMGNATHTGYACNGAYYTNTGGGAYTTYMGNGARTAYYTNACNGTN AARGCNGARMGNAAYATHACNATGACNAGYTAYATHGARGARTTYCCNGGNYTNATHCAY TTYATHTTYATHGAYMGNMGNYTNCAYCAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ACN YTNTGGCCNGAYAGYCARTAYYTNAARTAYCAYGAYGTNTAYCAYTAYAAYAGYGARGAR GAYYTNGARTTYGARTCNYTNTAYGCNGARCAYMGNGAYAARGGNAARTTYAARGCNACN ATGAGYTCNTTYGTNTCNCCNYTNAARAARAAYYTNGARCARTCNTTYCAYTCNTCNACN CCNGTNMGNTCNTCNCARAGYTTYYTNMGNMGNYTNGARCAYCARAARYTNTCNCCNATH AARGGNAGYAARTCNGAYGCNATHTTYAARCARCCNCAYTCNMGNYTNAAYAGYAARAGY CCNYTNAARMGNCAYTCNTCNTCN------CAYACNCCNACNTCNAGYCAR--------- ------------------------------------------------------CCNGAY MGNAARAGYCCNMGNAARYTN---------------------------------TCNMGN CAYTGGACNACNTGYCCNMGNYTNAAYYTNAAY------------------AGYCCNAAY TAYAGYTGYTCNGGNGAYGTNACNCCNCCNGTNTTYAAYAGYYTN--------------- ---------------------------------------------CARCARACNAAYTCN ATHATGCCNGTNAARMGNTCNYTNGCNGAYATHAARTCNCAYGGNGARCCN--------- GTNMGNMGNTCNCCNMGNAAR---CCNYTNTCNAAYYTNTCNACNTCNTTYCAYAAYAAR AGYAARAGYTTYTCNAAYTCNYTNGAYAGYGTNTTYCARCCNTCNAGYTCNACNCCNAAR GARTCNACN------------AARACNGTNGAYACNGAYAARTCNTCNAARATGAARMGN TCNGARMGNCAYAARYTNMGNYTNCARCAYATGATHAARACNGTNYTNAARAARAARGGN ATGGGNGARGAYGAYCCNYTNTTYCARTCNTGYGCNAARAAYYTNTTYAAYGTNAGYYTN ATHYTNYTNAARACNYTNCCNAAYTCNCARAAYYTNACNGCNGARATGGARAAYGTNGTN AAYGGNCARGTNCARCARATHATHAAYYTNGARAARMGNMGNGCNGGNATHGCNATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ACNTGYACNGGNCARGGNGTNCAYAGYMGNYTNAAYYTNTTYCARATHAAYCAYGAR GARTCNATHYTNATGTGYGARAAYGCNGARTGYACNTTYATGCCNTCNTCNGAYTGGAAY TCNYTNGTNGTNAARMGNGAYYTNTCNAARGTNAGYACNTCNAARAGYAARMGNTCNTTY ATHCCNTGGCCNAGYCAYAARAGYATHCAYAGYMGNAGYGGNCAYGTNAGYMGNGARATH ATHCAYAGYYTNACNGGNGCNTCNGARAARGCNATHATHGGNTGGTAYAAYTTYMGNCCN AARAGYACNTCNMGNCCNTCNYTNAARGARATGTCNATHCAYAARAGYYTNACNGTNYTN GGNAARCAYCCNTGGGAYTTYYTNTTYTTYYTNTGYACNTCNTCNATGTCNTCNAAYTTY TCNACNCAYTCNTCNGAYCAYTGYTTYCARATHGCNGTNAAYGGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYTTYAAYCAYNNNAARAARMGNAGYMGNAGY MGNGARAARAGYAARGARMGNMGNMGNTCNMGNAGYAARGAR------------------ ---------------------------------------------MGNMGNTCNMGNAGY MGNAGYAARGAYAARGARMGN---MGNMGNMGNGAYMGNGAYAARGAYAARGARMGNGAY MGNGARMGNAARGAYAGYMGNMGNMGNMGNAGYMGNTCNCCNMGNMGNMGNMGN------ ---------MGN------MGNGARCCNGARYTNACNGTNGARGARMGNGAYATHMGNACN GCNTTYTGYATGCARYTNTCNGCNMGNATHMGNCCNMGNGAYYTNGARGARTTYTTYTCN TCNGTNGGNAARGTNMGNGAYGTNMGNATHATHACNGAYAAYAARACNMGNMGNTCNAAR GGNATHTCNTAYGTNGARTTYGCNGAYCCNGARTCNGTNCCNYTNGCNATHGGNYTNACN GGNCARAARYTNYTNGGNGTNCCNATHYTNGTNCARCCNTCNCARGCNGARAARAAYMGN GCNYTNCCNGCNGCNCCNACNCCNGCNCARAARCAR---GTNACNGARGGNCCNYTNMGN YTNTAYGTNGGNTCNYTNCAYTTYAAYATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGGCNAARGCNACNGCNYTNGAYGAYGGNGGN GCNMGNMGNAARYTNGAYATGMGNCCNTCNAGYGCNTCNYTNAARYTNAGYGARGARYTN MGNGCNTCNACNGGNTGYYTNAAYAARMGNAGYATGGTNYTNGAYGARGARAARTTYCAR GAYCARTTYYTNAGYTGYCAYGTNTGYAARGAYMGNTTYACNAGYAGYAARACNCCNMGN YTNATGCCNTGYCAYCAYTCNTTYTGYYTNGAYTGYATHATGGCNATHTTYYTNAARACN MGNGAYCARMGNCAYAGYCAYYTNTCNTAYCCNMGNGCNACNGCNACN------TCNACN ACNAGYATGGCNTGYCCNATGTGYMGNGGNAAYTTYATGACNACNGARGAYGGNGTNAAR AARYTNCCNGCNGAYCAYMGNATHGTNCARYTNATHGAYTTYYTNMGNAGYACNAARAAR TGYACNGTNACNTTYTGYACNGTNCAYACNCARAAYCCNYTNAAYTTYTTYTGYGARYTN TGYGTNMGNCCNGTNTGYCAYGAYTGYATHGCNTCNGARCAYAGYGARAARGGNGGNCAY YTNGTNATHGAYYTNGARGARGCNATGGARAARTAYGARCCNATHYTNGAYGCNACNGTN ACNGARYTNGARGARGARGCNGTNAAYYTNGARGGNMGNAARAARGCNYTNGAYTCNATH TGYGCNTCNATGGAYAARGARGTNAAYAAYYTNATGGAYAAYATGAARAARAARYTNAAY MGNYTNMGNAARGARATHGAYATHGTNGARGCNGAYYTNGARAARAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYACNTTYTTYAARGAYTAYCCNMGNYTNATGTCN CARTCNGTNTAYTCNTCNTTYTGYTTYTCNTTYGCNGAYTCNTAYMGNCARTTYGGNGAR AGYTTYAARGAYGAYYTNYTNGCNYTNGTNTAYGGNTGGATGTCNGGNATHMGNCCNGCN CCNMGNAGYTGGATGGCNTGGGAYATGTCNACNYTNGARCCNCCNAAYATHMGNATGMGN GARGARYTNATGCARAARAARAAY---AARAARATGAGYTCNYTNATHGAYTTYGAYTAY YTNGAYTCNYTNYTNTCNACNAAYGCNAGYCARTAYGCNTCNACNATGTCNYTNGCNCAR TCNACNTCNAARTCNTCNGTNAAYTCNAAYATGGGNACNACN---MGNMGNAGYMGNGCN GTNGCNMGNYTNAAYAARGTNTCNCAYAARCCNGTNGTNMGNTCNTCNTCNCCNAAYAAY ATHYTNTCNCCNACNTCNTCNCARGAYTAYACNGCNATHGAYGCNGTNGCNGAYGCNCAR AAYGGNTCNGGNTTYAARGGNATHTCNAARGAY--------------------------- GGNAARGAYGCNAARMGNCCNAGYGARGCNYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARACNCCNGARMGNTAYYTNAARATHMGN AGYTAYATHYTNGAYTGYTGGAARAARTGYAARCCNTCNTAYYTNAAYAARACNTCNGTN MGNCCNGGNYTNAARAAYTGYGGNGAYGTNAAYTGYATHGGNMGNATHCAYTCNTAYYTN GARTGYGTNGGNGCNATHAAYTTYGGNTGYGARCARGCNATGTAYAARAAYCCNGGNYTN GGNGCNGGNGCNGGNGCNAAYAGYMGNGTNAAR---GGNATHAGYAARGARYTNYTNGCN GCNYTNCCNGTNACNAARTCNGARATGMGNCCNMGNAARMGNMGNATHMGNGAYGAYAGY GGNTTYTGGGTNGAYGARAARGARYTNGARGGNAARACNATHGARCAYGAYYTNGARATH AARAARAAYMGNAARCCNAARGTNCCNAARGCNGCNAARCCNGTNTAYGAYCCNTTYAAR YTNATGCCNTGYATGCCNTTYTCNGARGARAGYAARGARCCNTAYGGNATGGARGTNTTY AAYACNGCNYTNGCNATHATGGAYATHCAYGCNCAYATHTCNAARACNGARGTNATHGGN ATGYTNGGNGGNCARTTYTGYCCNGARACNAAYAARYTNACNATHAGYATGGCNGTNCCN TGYAARAGYATGAGYACNGGNATGCARTGYGARATGGAYCCNGTNTCNCARACNYTNGCN AGYGARCARATHGARGAYGTNGGNATGTCNGTNGTNGGNTGGTAYCAYTCNCAYCCNACN TTYAGYCCNGAYCCNTCNGTNMGNGAYATHGARACNCARCARAARTTYCARTAYTGGTTY TCNAARGGNGGNAGYCAYTTYGTNGGNGTNATHATHAGYCCNTAYAAYGTNTCNTCNCCN TCNGTNTAYTCNGAYATHMGNTGYYTNACNATHAGYAAYTCNCAYAAYAARGARTTYYTN TGYAAYATHCCNTAYAARTTYGAYTAYCARGTNGTNTAYMGNGAYAAYYTNMGNGARATH YTNGGNCCNGCNAGYGARYTNGCNGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GCNGTNCAYACNGARGAYATGGARYTNTAYAGYATHAAYTAYYTNCAYTAYGGN GCNCCNAARTCNTGGTAYTCNATHCCNCCNGARCAYGGNCARMGNYTNGARMGNYTNGCN CARGGNTTYTTYCCNGGNAGYTTYTCNGARTGYCCNGCNTTYYTNMGNCAYAARATGTCN YTNATHTCNCCNCAYATHYTNAARAARTAYTCNATHCCNGTNAARAARATHACNCARGAR GCNGGNGARATHATGATHACNTTYCCNTAYGGNTAYCAYGCNGGNTAYAAYCAYGGNTAY AAYTGYGCNGARTCNACNAAYTTYGCNACNGARMGNTGGATHGARTAYGGNAARMGNTGY YTNCARTGYATHTGYMGNMGNGAYGGNGTNAARATHAGYATGGAYGTNTTYGTNAARAAR TAYCARCCNGAYMGNTAYGARYTNTGGAARGCNGGNAARGAYATHGCNTGYCAYCCNGAR GGNCAYAARGAYGGNAAYMGNGCNTCNGCNAAYMGNAAYAAYMGNAARAARATHGARGCN AAYAGYTCNGGNACNGCNCAYTCNMGNMGNCAYCCNYTNAARGARGAYTTYCCNGCNAAR GAYTGYAARAARGARAAYGTNAARGAYTCNACNCCNAGYAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHGCNMGNTGGYTNCCNCARTAYMGNTGYGAYACNTTYCARGCNGAY YTNATHGCNGGNYTNACNGTNGGNYTNACNGTNATHCCNCARGGNYTNGCNTAYGCNCAR ATHGCNAAYYTNCCNGCNCARTAYGGNYTNTAYTCNGCNTTYATGGGNGGNTTYGTNTAY GCNYTNATGGGNACNGCNAARGAYATHACN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TTYTAYMGNYTNTGYTAYGAYAGYGARAGYCARAARGTNAARTGYTCNYTN ACNGGNCAYGARATGCCNGCNACNACNATHGCNATHGARAGYTAYGTNAARGGNATGAAR TAYAARAARCARTCNGARAARAAYACNTAYAGYTAYGARMGNCAYAARGCNCAYATHATH MGNAGYGTNAARAARAARCAYCARCAYGARYTNTTYTGYAARYTNACNYTNMGNCAYATH GGNAAYTCNCCNCARGAYATHGARMGNCAYATHACNGGNAARAARTAYACNAARGCNYTN AARMGNTGGGARCAYTGYAARGCNACNGGNGARAARTTYTAYCCNAARGCN---ACNMGN CCNTCNAARTCNAARGARTCNGGNAAYGAYAGYATHGAYAGYACNGARMGNCCNTGGGAR GAYTCNGAYGARGAYCARACNGGNAGYGAYGAYATGAGYGAYYTNTAYCCNGCNGARGAY TTYGCNGTNCARCCNTCNGARAAYGARGARGARGARTCNCARGAYGARGAYGARGARAGY GTNAAYTCN--------------------------------------------------- ------------------------------------------------------------ MGNTGGAARTAYYTNCCNCCNGGNACNATGGGNTGGCCNGTNGTNGGNGARACNYTNCAY TTYYTNGCNAARGGNTCNGCNTTYTAYYTNGARMGNTTYTCNAARTAYGGNACNATHTAY AARACNCAYYTNYTNGGNMGNCCNACNGTNMGNGTNTCNGGNGCNGAYAARYTNMGNACN YTNATHAGYMGNGARCCNAARTCNYTNACNATGTTYTGGCCNMGNGCNGTNMGNYTNYTN TTYGGNGARCAYAGYYTNGCNGTNGTNACNGGNGCNGARACNGCNCCNYTNAARAARACN YTNYTNAARACNATGACNCCNAAYMGNYTNTCNGAYTAYYTNCCNTGYGTNCARCARCAY ATHMGNTCNCAYATHACNTCNTGGAARGAYMGNGGN------------MGNATGYTNGGN TTYCCNGCNTGYGARGAYGTNGTNACNGAYATHATGYTNGARYTNGTNYTNGGNTGYMGN AARGARAAYGAYCCNAGYMGNAARGTNMGNGAYGCNYTNGTNGAYGTNAAYAAYAAYYTN TTYAGYYTNCCNTTYTGYATHCCNGGNGGNGGNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATHYTNGCNGCNTTYMGNAAYYTNCAYAARGCNMGNAAR GARGTNTTYGCNGGNGAYGTNMGNGCNYTNGCNGARACNMGNCARCARATHAAYAGYGAR TTYMGNAARAAYYTNAAYGARCCNGAYTCNTCNAARATHAAYGARYTNYTNACNYTNGCN ACNGAYGTNGCNCAYYTNYTNMGNACNACNGTNGTNCARYTNMGNCARAARGARAGYGAY GAYAGYACNTTYGARYTNMGNGTNMGNAARAGYGTNAAYYTNCCNACNTAYGARCCNTAY GAYCCNACNAARGARATHCCNYTNAARGTNMGNAAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATHTTYCAR CAYATHTGYATHCARCARATHATGTCNATHGARCCNGARAAYAARYTNTGGAARMGNGAR MGNCCNATHTAYCAYGGNGGNGCNTTYMGNAGYTAYYTNAARGAYCCNGARGARGAYGGN GTNATHCAYAARYTNGAYCAYGGNCCNTGYGTNTGYCCNCARTGYCAYYTNCAYTGYGAY CARAGYGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TTYTAYYTNCARCAYGCNGTNYTNAGYACNYTNMGNAAYYTNGCNATHCCNGCNGCNAAY AARTCNMGNYTNCARAARGCNGGNGTNATGGAYGCNTGYYTNTGYYTNATHAAYTCNGAR GTNATGGCNGTNGTNTTYAARYTNYTNGGNGTNATGMGNATGYTNATHGARGGNCARCAR GCNGCNGCNGTNAARYTNGGNCARGARMGNAAYTTYYTNGAYTGYYTNTCNGAYTGGTGY ACNGTNGARGCNCAYGCNGGNGTNAARGGNGARGCNCCNMGNGTNATHGCNTCNYTNGTN AARAAYAGYMGNTCNTCNGCNGTNGTNCARAAYYTNATHMGNGCNGARTGYATGGGNCCN YTNGTNGCNATGGCNATGTGYGARCAYMGNGTNATGCARAAYGARGCNATHATGGCNYTN ACNATHGTNTCNTCNYTNTGYYTNACNGARGCNGCNGTNGCNYTNMGNGARGCNGAYYTN GCNGARACNATHGCNAARYTNYTNAARGAYGARACNTTYCCNGCNGAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATHAAYGGNTGYGTNGCN GAYTTYCAYYTNGARATHAARAARGGNYTNGAYGARAARGAYGGNGCNYTNTTYTAYAGY YTNGTNAAYACNGTNGARACNCARATHTCNMGNATGTCNTCNACNTAYTCNCCNAAYGAR YTNGARYTNTTYAARAARATGATHGARAARATHGTNCARTCNGARGAYGGNMGNATHGGN TCNYTNGCNGCNCAYMGNYTNACNGGNAARYTNGAYAARAARATGAGYATHGARGARGCN GARAAYTTYTTYAAYGAYYTNGARAARAAYAARTGGATHGARAARAAY---CARGGNCAR ATHTCNYTNTCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AARATHAGYATH ACNGGNTAYGCNMGNACNCARAGYGAYCARGTNTAYGARCARTTYYTNMGNYTNMGNTAY AAYYTNACNYTNTGYGTNAAYGARGCNGARTTYGTNGTNACNACNYTNTCNYTNCCNTTY YTNGTNTCNACNGGNGCNATHCARAAYYTNGARYTNATHGGNTCNCAYATGTGGTAYATH GCNAAYAGYGAYYTNTAYAAYGGNGAYTTYMGNGTNCCNGAYAGYGTNCCNGTNGARAAR GTNYTNGAYATGYTNAAYATGMGNATGCCNTCNACNAARGAYAARAARMGNCCNYTNTCN CARACNGCNMGNCARYTNYTNAARGAYMGNYTNGCNGCNCAYTCNGAYGGNATGGTNAGY YTNMGNAGYTTYATHAARCCNACNGARMGNGTNAARMGNAARAARACNGAYACNGCNCCN AAYCARGARAGYTTYTTYACNTGGTTYTAYGCNYTNGTNAAYACNATHGARAAYTCNYTN YTNACNGCNTGGACNGAYGGNATHATHTAYGARYTNATGACNTAYGARGAYGCNTGYCAR YTNYTNATGAARGARGAYATHCCNGARGGNACNTGYGCNATHMGNTTYCARYTNTCNAAR GTNYTNGTNCCNAAYTCNYTNGAYGCNCAYGTNMGNATHGTNGTNGARATHAARGTNAAR GARGAYGGNAARTAYCARATHGCNCCNGTNCCNATHGAYGTNYTNACNAAYAAYAARAAY ACNYTNTAYCAYACNGTNACNTCNATHGTNTGY--------------------------- ------------------------------------------------------------ ---------------------------------------------------ATHTCNAAR YTNGAYGTNAARATHYTNCAYYTNCCNACNAGYAAYCCNTGYCARGAYTTYTTYYTNAAR GARMGNMGNTGYTGYYTNTTYGGNGARAGYATHMGNCCNTGYGAYTTYGGNTTY---YTN CCNGCNACNGGNGCNATHGARTCNYTNYTNGCNAARYTNTCNTCNGARACNYTNACNAGY GTNYTNTCNAGYMGNGTNATHTGYTCNTGYTTYAAYAGYATHTCNAAYCCNATHTGYATH CARAARTGGYTNTTYTAYYTNATGTCNATHCAYACNGAYCCNYTNATGGTNAAYTTYTGY TAYATHAAYYTNAGYAAYATHATHCARCARYTNACNACNAAY------------AGYGAY GTNMGNAAYAARATHTGGTGGCCNAARCCNCARGARYTNTTYCARGTNYTNGTNAAYYTN GGNGCNAGYCCNAAYGARYTNAGYAARAAYGAYACNTTYTAYAAYACNAARGAYAGYGAR ATHYTNAARCCNTGGCARCARTCNGAYATHCAYGGNCARGARAGYMGNCAR---GAYGAY ATHTCNACNGARAAYGTNAARTGYYTNYTNAAYGCNYTNTCNYTNTAYYTNCARTCNMGN TCNTCNTAYAGYAAYGARGARYTNCARTTYTTYGTNTTYATGGTNATGAARATGTCNYTN GAYGTNMGNYTNAAYGGNTCN---YTNATHMGNGARTTYCARGTNTGYATHGCNTCNYTN YTNCAYTGYTAYCARGARTCNGARTGGTCNAARGTNGTNCCNGARYTNAGYGAYYTNATG TCNACNYTNACNAGYCAYCAYCAYACNGCNGTNTAYYTNTGYCARATGYTNCCNTTYTGY GARMGNGGNYTNGARATHCARMGNCARATGAGYTTYTGYTGGYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GAYCCNAAR AARGGNGTNGTNAAYAAYCARATHYTNGAYTGGTCNTTYAARYTNGAYGGNATHTTYAGY AAYGCNGAYCARGARCARGTNTAYGAYACNGTNGCNTCNGAYATHGTNACNGGNACNYTN GAYGGNTAYAAYGGNACNYTNATGTGYTAYGGNCARACNGGNGCNGGNAARACNTTYACN ATGACNGGNGCNACNGARAGYTAYMGNCAYMGNGGNYTNATHCCNMGNGCNATHTCNCAR YTNTTYMGNTCNATHGARGAYMGNYTNGARTAYAGYATHACNGTNMGNGTNTCNTAYATG GARATHTAYAAYGARGGNATGTTYGAYYTNYTNGGNTGYGTNAAYGARCARTCNTGGAAR ---------AARGAYCCNAAYGCNGGNCCNGAYCCNATGGTNATHTCNGARAAYCARAGY GGNGTNTTYGTNAARGGNYTNTCNTGYCAYYTNGCNCARAAYGARGARGARGCNYTNAAY YTNYTNTTYGARGGNGARACNACNMGNACNATHGCNGCNCAYCARYTNAAYAARCARTCN TCNMGNTCNCAYTGYATHTTYACNGTNCAYYTNGARTCNMGNTCNMGNATHCARTCNAAY GCNAARTAYACNGTNTCNAARYTNAAYTTYGTNGAYYTNGCNGGNTCNGARMGNYTNGGN AARACNAARTCNGARGGNAARACNAARGARGARGCNATGTAYATHAAYAARTCNYTNTCN TTYYTNGARCARGTNGTNGTNGCNYTNGCNTCNAARACNMGNGARCAYGTNCCNTTYMGN CARTCNAARYTNACNCAYTAYYTNAARGAYTCNATHGGNGGNAAYTGYAAYACNYTNYTN ATHGCNAAYATGTGGGGNGARAARCARCARYTNGARGARTCNGTNTCNACNYTNMGNTTY GCNACNMGNATGATGTGYGTNGCNAGYAAYGCNGCNGTNAAYGARGTNTCNGAYCCNGTN YTNATGGTNAARAARYTNCARMGNGARATHGCNCAYYTNAARTCNGARYTNGCNATGCAY GAYACNYTNACNAAYMGNAGYATGATHTCNTAYGAYCCNYTNTCNGARCARCARAARTAY GARATHMGNTCNCARGTNMGNMGNTAYYTNGARGGNAGYYTNGAYGARATHGAYGTNGTN AAYYTNMGNCARATHGTNGGNACNTTYGAYACNTTYAARGAYYTNTAYAAYGAYATGGAR MGNGARATGGARGCNMGNYTNMGNGARAARTTYACNYTNATHGAYAARACNGAYCCNGCN TCNATHGCNGCNGCNCARCARGARTTYGCNYTNGCNGCNGARCARAGYTCNGGNYTNCCN GAYCARGCNGGNYTNCCNATHGCNGAYGAYGGNACNYTNGTNGGNGAYYTNGAYGGNGGN GGNTTYGGNGTNGGNACNTCNCAYMGNGCNACNMGNMGNGAYGTNTCNGCNGTNGTNCAR YTNAARMGNAAYGARMGNGARMGNGAYMGNMGNMGNGGN---YTNTCNACNMGNTCNCCN GTNGCNGGNAAYACNGCNTCNAGYCCNTCNCARAGYGTNAARGGNGARMGNAARGARGAY TCNTCNCCNATHYTNGCNGCNGARMGNGCNGARAARGAYAARGARGGNGAYGGNGGNTCN ACNTCNCCNGTNAGYTCNACNGGNAAYYTNTCNMGNGCNGAYAARACNCARMGNCCNAGY ---------------------------------------------------ACNCCNCCN TCNMGNACNTCNGCNTTYGARGARTTYAARGCNGAYMGNGGNAGYGARATHAAYMGNATH YTNGTNCARAAYAARGAYATHYTNACNAGYAARAARAARGARTAYTCNGAYYTNGCNGGN CAYATHAAYTCNGTNAARYTNTCNATHGAYAGYAGYMGNMGNMGNYTNGARCARYTNCAR CARCARMGNGARGCNGAYGGNCCNATHYTNAAYGARGAYGGNGAYATHGTNATHAGYGAR GARGARTTYATGGARATHAAYCARYTNAARGARYTNAARGCNTCNTAYMGNAAYAARCAY CARGARYTNAAYAAYYTNAARTCNGARGTNTTYTAYTGYCARAARCARGTNGAYGGNACN MGNYTNMGNYTNATHACNGARTTYGAYAAYTGGTAYGCNGAYAGYTTYYTNTCNTCNGCN GAYGARACNCARACNAGYYTNGGNGCNGGNCAYGGNGTNMGNCCNGGNGTNATHGTNCCN ATHACNAGYYTNGCNCCNGARGAYGARCARGARAARTTYGARMGNYTNCARYTNGARYTN ATGATGAAYGAYCCNGARTCNGCNGCNTTYTAYAAYGCNCARATGMGNACNAAYMGNMGN AARTCNTAYGGNGCNGCNYTNAGYCARGCNCARCCNGCNTAYMGNMGNCARCCNGGNACN CCNACNGTNGCNATHYTNAAYCARCCNCCNMGNATGACNCARGTNCARTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARATHGAYTAYATHYTNAAYGARAARGTNTGYAARACNGAYGARAAY AGYGTNACNTTYATHAGYAAYAGYTTYCAYGCNCARCCNGCNGARAARCCNAARCCNCAR GTNAARGARCARAARAAR------------------------TCNGAYGAYGAYGAYATH ATHATHATGGAYACNCCNGCNAGYACNAAYACNACNATHCCNACNMGNGARGAYCARAAY GCNGTNGCNCAYTCNAARACNAAYMGNCCNACNGGNGTNAARMGNCCNCAYGGNCCNAAY TCN------TCNAAYMGNAAYTTYGCNAARCARATGMGNACNGAYCCNTCN------AAY CCNAAYGGNGTNCAYCARAAYTCNAAYGAYTCNGAYAGYTCNYTNACNTTYYTNCARTCN GGNGTNTCNGCNYTNTCNGARTCNGAYATHTCNCAYYTNTCNCARGTNTTYCCNCARAGY YTNGAYACNTCNAAYGCNCARGARGAYGTNAARCCNAAYYTNGARAGYGAYYTNAARTTY GTNAAYGTNAARCARGARTAYGAYTCNTCNYTNCARGTNCARGGNGARGARGARCARGAY AAYAGYCARGARAGYAGYTAYTAYTCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNATHCARCAYTGYGTN GGNGAYATHAAYAARGTNCAYGARATHCAYYTNAAY---AARACNMGN---AARYTNYTN ATHMGNYTNAARGAYGAYGTNACNMGNGARGARYTNGARAGYYTNAAYCCNAAYTTYGAY YTNATGGTNAARTCNGARCAYTCNGAYACNGTNTCNGGNGTNGGNATHACNYTNAARGGN ACNGCNAGYAAYGGNTGYATHAGYTCNGAYGGNCARGTNTAYGAYTTYGTNTCNMGNTAY TTYGCNCCNTGGGTNGGNATHCCNGARGAYCCNGTNACNGGNTCNTGGCAYACNGTNGCN GCNCCNTTYTGGTCNACNGTNYTNAAYAARTCN--------------------------- ------------------------------------------------------------ ------------------------------ATGGGNACNAAYCCNAARAARCARTCNAAR TCNTTYAARGTNYTNCARTGGATGACNGARACNAGYMGNGARGAYGARGCNGARGARGAR GAR---------------------------------------GCNAARCCNAARGCNAAR MGNAAYGGNGARGARGARGTNGARATGAARTTYMGNGGNACNCAYGCNMGNACNGAYATH CCNTCNAARACNTTYGGNMGNYTNAARAARTTYGCNGAYAAYGCNGAYGARYTNCCNAGY GARCARGGNAAYGGNACNGARCAYGAYGAYAAYGCNGARGARACNGTNGGNAAYTAYAAY GARTCNTCNATHMGNTAYMGNGGNAARCAYATHCCNTCNCCNTCNTTYMGNGTNYTNCAR AAYTGGGCNGARYTNGAYCCNGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GGNTTYGTNTAYGAYGAYGGNAGYATHYTNYTNATG GAYTAYGTNAARAAYGGNTCNYTNYTNAAYYTNGTNAAYAARTAYAARAAYGAYCAYTCN ATGYTNGCNAAYGTNGARCCNTTYGCNTGYYTNGTNACNATHAARYTNYTNCAYYTNATH GARCARATHCAYAARTGYAARATGATHCAYGGNGAYATHAARCCNGAYAAYTTYYTNYTN YTNGAYYTNCCNATHATHCCNCAYGGNACNGAYCCNYTNGAYGTNGTNAAYAGY------ CCNYTNTTYGCNYTNACNGAYTTYGGNCARGGNATHGAYYTNAGYAARTAYCCNGAYGAY ACNAAYTTYATGGCNAARYTNGCNACNTCNGGNTTYCARTGYATHGARATGAARACNAAY MGNCCNTGGAAYTTYCARGTNGAYYTNTTYGGNYTNGCNGGNACNGTNCAYGTNATHYTN TTYGGNTGYTAYATGAARGTNTTYCARGARMGNGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGGNAAYGGNATG AAYAARATHYTNCAYGGNYTNTAYGTNGGNAAYTTYMGNGAYGCNAARGAYAARCARCAR YTNGAYGARAAYAAYATHACNCAYATHGTNTCNATHCAYGAYAAYGCNAARAARYTNYTN GARGAYAARGARTAYYTNTGYATHYTNGCNTCNGAYTCNCCNGAYCARGAYYTNACNAAR TTYTTYCCNCARGTNATHGCNTTYATHCAYAARGCNMGNYTNGARGGNGGNTCNGTNGTN GTNCAYTGYYTNGCNGGNGTNTCNMGNAGYGTNACNGTNACNGCNGCNTAYATHATGACN GTNACNACNYTNMGNTGGMGNGARGCNYTNAAYTCNATHMGNGGNGCNMGNAGYGTNGCN AAYCCNAAYTAYGGNTTYCARAARCARYTNCARAARTAYGARAGYGARCAYGTNGARCAR GARMGNAAYAARYTNAARGCNCARTAYCCNCCNAAYCCNTAYGAYGAYGARGCNGARTGY MGNCARAAYYTNAARTGYTTYCARCAYTTYATHATGACNGGNACNACNGGNGCNCARTCN GARCARYTNTAYCCNYTNCCNTAYAARGCNTAYGARTCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGCNCARYTNGGNCARGCNATHTTY ACNYTNCARGARATHYTNYTNTCNCCNGAYYTNACNYTNCAYYTNACNYTNAARTCNCAY GAYGGNAAYGTNGCNGTNACNGCNTGGATHAAYGAYGAYAARGTNTCNYTNACNCARYTN MGNAARCARCARAARGGNTCNTAYAGYAARMGNCCNMGNACNATGTCNYTNGGNMGNCAY TCNCAYAAYYTNCARTCNCAYTTYGCNTCNGTNYTNAARMGNTCNTTYMGNTTYGCNACN AAYGAYGARAARTCNYTNCARGTNTCNGARTAYATGGGNGARAGYAARTGGTGYTTYGAY ATHCCNGTNCARYTNYTNAARYTNTGGGTNTCNGARGARAARMGNATGATHACNATHYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNTGGCCNGARGCNAARGTNGARGTNTTY GGNAGYTTYMGNACNGGNYTNTAYYTNCCNACNAGYGAYATHGAYYTNGTNGTNTTYGGN AARTGGGAYTCNCARCCNYTNTGGACNYTNCAYGAYGCNYTNYTNAARCARAARATHGCN GAYCCNGCNTCNATHAARGTNYTNGAYAARGCNTCNGTNCCNATHGTNAARYTNACNGAY GCNGCNACNGARGTNAARGTNGARACNMGNTAYTGYACNAAYTGYAARMGNGAYATHTCN GTNGCNAAYTTYGTNATGCAYGARGTNCAYTGYMGNMGNCAYATHATHYTNTGYCARCAY TGYGAYGAYGCNATHCCNAARCARGARATGGARCARCAYTAYAAYGAYYTNCAYGCNCCN ATGCCNTGYGCNYTNTGYAARAARCARATHACNAARGAYAARATGGARAARCAYYTNGAR YTNGARTGYMGNCARAARCCNATHMGNTGYGARTAYTGYGARYTNTCNTTYCCNAARGAR CARATHGARGCNCAYACNGGNTAYTGYGGNAGYMGNACNGARTGYTGYCCNYTNTGYAAR CARTAYATHATGYTNAARGAYATGATHCARCAYGARAGYTCNGGNTGYTCNTGYCCNGAR CCNAARCCNGCNGCNCCNAGYGCNGCNTCNGAYCCNTTYAAYATGGCNTCNYTNGGNGAR TAYYTNGAYCCNCARAAY---GGNYTNAAYGARAAYTTYCCNGARTTYGTNGARAAYCAY TAYGGNGARGGNMGNCARGAYTTYGTNGCNTCNYTNYTNAARGAYTCNMGNMGNCAYGAR TCNMGNGCNAAYGGNMGNMGNTCNTCNMGNAARAARAAYACNAAYTTYGAYMGNGAYAAR GGNAAYGTNCCNACNGAYTGGATHCCNCCNGARYTNGAYTAYGAYACNATGYTNGCNYTN CARYTNGCNCAYGAYGAYTGGGCNCARGAY---AARGCNGARCAYGTNAGYACNCARGAR ATHGCNMGNGGNAARTGGATHGCNYTNAAYAAYGTNACNTAYMGNGAYCCNAARGGNMGN GARMGNYTNTGGGARAGYGTNTCNMGNACNACNAARCARACNAAYACNGCNGAYGCNGTN TGYGTNATHACNGARTTYTTYGAYCCNATHCARGGNTGYCARTGYGTNATHYTNGCNMGN CARTAYMGNCCNCCNYTNAARACNACNACNATHGARTTYCCNGCNGGNYTNATHGAYGCN GGNGARACNGCNGGNCARGCNGCNGTNMGNGARATGAARGARGARACNGGNTAYGAYGTN ACNATHAARACNGTNTCNCCNATGACNGCNYTNGAYACNGGNGTNAGYAAYACNACNYTN GTNYTNGTNACNAGYGARATGGAYCCNAAYATGGAYYTN---TCNAARMGNCCNGCNCCN ACNACNGAYGCNCCNGAYGARTTYATHGARGTNATHGTNCARCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------YTNACNAAYGARYTN AARGAYTCNACNGAYYTNATHYTNACNAARYTNGARTTYYTNGAYATHACNGTNGARAGY TTYTCNAARYTNCARGTNYTNTGYATHGARYTNAARACNMGNTAYATHGAYTGGACNGCN AGYGARYTNACNACNTCNTAYTTYMGNAGYCARYTNCARCARGCNGARGGNGTNYTNGCN CARTAYGARCARAGYGCNGTNCCNGCNGGNTGGGCNMGNCARTGGGAYMGNGCNAAYCAR MGNTAYTGYTTYMGNAAYYTNGARACNAAYMGNATGCARTGGGAYAAYCCNGAR---ACN GAYCCNMGNCCNCCNAARMGNGAYAARMGNGGNAGYTCNTCNCARTCNAARGGNMGNGAY AGYATHAARGAYACNGGNGAYAAYGARCAYAGYMGNAARAARYTNTCNAGYAGYMGNCAY MGNAARMGNGARGAYAARGARAAR------------------AGYAARMGNGAYMGNMGN GGN---GGNTCNCAYCAYMGNMGNAARAARMGNMGNMGNCAYMGNGAYCAYAGYAGYAGY AGYAGYAAYAGYCARGARAGYGCN---------------CAYCAYCAYAARAGYAARMGN AARAARMGNAGYAARMGNTCNAARTCNCCNAGYGTNGARATHGTNGGNGAYACNCAYGTN GAYGAYGTNCAYATHGGNTCNGARAGYCCNACNCCNGTNACNYTNAGYCCNGARCCNGAR CCN------------------GCNATGGARATHGTNATHGAYTGYYTNAARGARGGNGAR GGNGARCCNATH------------GARGARGGNATHGARYTNCCNCCNATHGTNMGNGAR CCNGGNGCNACNGCNYTNGARGAYGCNGTNGTNGGNGCNGTNGCNAGYGAYGAYATHGAY GGNCARGTNATGGARGAYGAYGGNGARGARAARGGNGARGARGARAARGTNGARGARGAR GTNAAYTCNGCNGTNATHYTNAARCCNCCNCARATHATHCAYCCNCCNGTNTCNGTNGCN YTNGTNTCNCARCARGARTAYTGYGCNCCNCCNGTN---CCNCCNGCNCCNCCNGCNACN GCNGCNCCN---------CCNAAYGAYATHAAYGGNGARCCNATGGARGAYGGNGAYAAR GCNTCNMGNAARAARAARGARAARAARGAY------------AARTCNYTNACNACNGGN CAYAGYATHATGATGAARAARAARMGNGTNTCNTCNATGGTNCARAARTGGCARCARGTN AARAARGARGTNGARAARGARGAYMGNGAYAARGARYTNMGNCARGCNGCNATHMGNCAR AARATHAAYGARYTNAARYTNGTNTTYMGNATHAAYGAYAAYGGNGTNGGNCCNGARYTN YTNCARCARGTNTTYATGGARMGNGGNTGGGTNGARTAYGAYGARGARATHCAYGGNGAR AAYGGNTGGAAYGTNTAYTGGMGNACNTCNMGNTTYMGNACNAGYGARTAYTCNAAYATG ATGCCNTGGCARTGGATHAAYCAYTTYCCNAAYTGYTCNGTNATGACNMGNAARGAYGCN YTNTGYMGNAAYATGMGNAARATGMGNGTNGTNCAYGGNCCNCAYACNTTYAAYTTYAGY CCNYTNGCNTAYAAYYTNCCNAAYGAYTAYACNAARTTYGTNGCNGAYTAYGCNAARYTN AARCARGAYAGYCARGARAARGGNACNGARGCNATGTGGATHTGYAARCCNGCNGARTCN TCNMGNGGNMGNGGNATHTTYATHTTYAGYAARYTNGARGAYYTNCARTAYGAYTGYAAY GCNGTNGTNCARCARTAYATHGCNGAYCCNYTNYTNATHGGNGGNTAYAARTTYGAYYTN MGNGTNTAYGTNTCNGTNCCNAGYTTYAAYCCNYTNAARGTNTAYATHCAYGARGARGGN YTNGTNMGNTTYAGYACNGARAARTAYGAYYTNMGNTGYYTNAAYAAYGTNTTYGCNCAY YTNACNAAYACNAGYATHAAYAARCAYGGNCCNAGYTAYACNATGGAYAARGARGARGTN GGNCAYGGNTGYAARTGGACNATHACNCARYTNMGNMGNTAYTTYYTNCARMGNAAYATH GAYGAYTTYYTNYTNTGGGTNGARATHACNAAYATHATHGTNYTNACNYTNYTNATGCAR GCNTCNACNGCNCCNAARTTYAAYAAYTGYTTYGARYTNTAYGGNTTYGAYATHYTNGTN GAYAGYTCNYTNAARCCNTGGYTNYTNGARGTNAAYTTYAGYCCNGCNYTNACNTCNGAY TGYCARGCNGAYYTNGTNGCNAARAARGCNATGYTNCAYGAYYTNATGGAYATGGTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CCNATHACNYTNGAYCARMGNGAYCCN TAYTGYAGYGCNGTNGGNATGCAYTTYAAYCARATGTTYCAYMGNTAYGGNTCNCCNGTN ATHGTNYTNAAYYTNGTNAARACNMGNGARMGNAARAARCAYGARAGYATHYTNAGYGTN GAYTAYGTNGAYACNYTNCAYTAYYTNAAYCARTTYYTNCCNCCNGARCAYCAYATHCAR TAYATHGGNTTYGAYATGGCNMGNATHAAYAARMGNAARGAYGCNGAYGTNATGATGMGN YTNGAYMGNATHGCNYTNTTYTGYYTNMGNCARACNGGNTTYTTYYTNAGYGTNCARCCN CCNCARGCNGGNTAYYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNTGGTCNAARCARCCNGTNTCNYTNTGG--- ---------GGNATGGAYCCNATHAAYGCNATGGCNCARGCNCARYTNGARAARATGAAR MGNGARGGNGARGARGARMGNGCNMGNGARGARGARMGNATHMGNGTNCARGARYTNGAR ACNAARCARAARGARYTNCARAARCARCARGAYGARATHTCNMGNCARAARGARCARATG AARMGNGARAARGARGARATGGARMGNMGNAARATHCARAAYYTNGARGARACNMGNAAR GARGARGARTCNATHCARCAYGAYATGGARAARAARMGNAAR------------------ ------------------------------------GARGARGARMGNMGNMGNCARGAR GARGARMGNAARCARGARGARGARAARAARMGNCARAARGARYTNAARAARCARGARGAR AARMGNAARAARGARGAR------------------------------GARAARYTNMGN GCNCARGARGARCARMGN---------------------AARAARCARGARCARMGNAAR CARCARGARGARYTNMGNMGNCARGARGARGTNGARGARYTNMGNYTNCARAARGARAAR GARYTNGARGARCARMGNGARGARGARGARMGNGARMGNMGNGARAAYGARMGNAARCAR CARCARGARYTNCARAARCARCARGARTCNYTNMGNMGNYTNCARCARCARCARCARCAR AAYYTNGCNAAYATGCARYTNCCNGCNGCNAGYAAYTGGGCNAGYCARMGNACNGCNCAR GGNATGCAYGGNCAYTCNAARTCNYTNATGGARATHCARGARGARGARACNYTNAARGAR ATHGARMGNCARCARGARCAYGARGCNCARATGATGMGNATGCAYGARCAYGCNGTNYTN CARACNCARCARATHCARCARAARACNTGGGCNTCNCAYACNGCNCARGGNGTNGCNMGN GGNCCNTCNYTNYTNGAYATHCARCARCARGARCARGARAAYGCNAARATGAARATGAAR GARGCNAARGCNCARATHAAYCARTCNAARTCNCCNYTNGCNAGYGCNCCNACNTGG--- TCNGGNGCNAAYTCNGCNAGYATHTGGGGNTCNCAR------------------------ ------------CCNATHTGGGAYGCNAGYGCNCCNAGYTCNGTNAAYTCNGGNACNGCN GGNACNACNAAYAARCCNGTNATHAARGARAGYGGNGARTTYCCNGCNYTNAARAAYCAR AGYCARCARGGNAARAARAAYTCNGCNAARGCNAGYAARAARGCNGGNTCNTCNAARYTN AARGARGARGARACNGTNCARAARYTNTTYCARMGNCAR---CARGAYGGNTTYGCNAGY TGGGTNACNGARMGNGTNAARAARTTYTCNGCNCARATHGAYGTNCCNACNTTYGTNTCN TTYATHATHGARGTNGAYAGYCCNGAYGAYGTNMGNGAYTAYGTNAARATGTAYYTNGGN GARAGYAARGARGCNAARGAYTTYGCNAARCARTTYGTNGARAAYMGNAGYAARTTYMGN AAYCARGCNMGNYTNGARAARCARCARGARGARGAYAGYATHTGGGGNCCNGCNCCNGCN ATHAAYCCNCAYAGYCARAGYCARGGNGGNGGNAGYAAYTCNGGNAAYTCNGCNAGYCAR AGYAARGGNAARAAYAARAARAARAARAARATGCARAARYTNGAYGGNAGYGTNYTNGGN TTYACNGTNCAYGCNGAYCCNAAYMGNAARAAYGCNGGNGARGTNGARAGY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGN------GAYCAYGGN AAYAARMGNTTYAGYTAYCARGCNACNAARCARCARYTNGCNGARGARMGNMGNMGNGAR TAYAAYGAYYTNATGCARGCNAARAAYCARAAYTCNGGNMGNMGNMGNGARAARGARATH GAYGARCCNTCNATHATHCCNTTY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN TGGMGNYTNGTNGARCARTAYGTNCCNCARCAYGARCARGARGARGTNAARAGYATGYTN GGNTCNCAYATHGTNGAYCARAGYYTNGARYTNCAYGARGARATHGAYATGYTNYTNGAR ATHTGGMGNGAYYTNMGNGAYGARYTNGCNGARGCNACNYTNCCNGTNMGNAGYYTNCCN GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GCNTCNGARGCNTGY AAYAARGCNAAYGARGARTAYGTNAAYGARAAYTAYCARAARGCNGTNGAYYTNTAYTCN GARGCNYTNACNYTNGAYAGYAARMGNGAYGAYGTNTAYTGYCAYMGNGCNCARGCNTAY YTNCARYTNGGNGAYGCNAARAAYGCNGTNGCNGAYTGYGAYAARGCNATHGARYTNAAY GARAAYAAYGGNAARGCNTAYYTNAARAARGGNTCNGCNYTNTAYCARATGAAYGAYATH YTNAGYGCNYTNGAYGTNTTYAARAARGGNCAYAARMGNTTYGARGAYGAYAARCAYTTY GGNGAYTGGGTNAAYAARTGYGARGGNCARYTNAARAARGGNGGNACNGCNACNGCNCAR CCN---ACNGCNGCNTCNGCNCCNGCNACNGARATHCCNGARATHGCNAARGTNMGNTAY GAYTGGTAYCARACNCAYACNCAYGTNATHGTNACNGTNYTNYTNAARAAYGTNAARAAR GARAAYYTNGAYGTNGAYACNAARAAYMGNAARATGACNGTNAGYGTNAARAAYCCNGAR TCNACN---------YTNAGYYTNGAYYTNYTNCAYGAYATHTCNCCNGAYCARACNCAR ATHAARYTNTAYGCNTCNAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG GAYMGNMGNTTYATHCAYAGYAARYTNTCNCCNCARACNACNTTYMGNGAYCARAAYAGY YTNGGNYTNGCNGCNTGYTCNTTYGAYTGYGGNGCNAAYAAYATHTTYYTNGGNTCNTTY ACNGGNGARYTNMGNGCNGTNTCNTCNACNAGYACNGGNGAYGAYYTNTGYATHACNCAR TGYCAYTCNTCNCCNGTNATHCAYATHAGYACNTCNCAYGTNAAYCCNGAYYTNGTNTTY ACNGGNACNTGGGAYTCNGTNCARAAYTGYGCNYTNTGGGARTTYGAYMGNAARATGACN GCNTTYAARYTNAARTAYMGNYTNGAYGARTCNATHGCNTAYYTNGCNAAYYTNAGYCAY GAYCAYTTYATHGGNACNAAYGGNCCNAARGCNACNATHTAYGAYACNTCNACNGGNGAY AARGTNCARACNYTNTTYGAYGARAGYAARGCNAAYAAYTAYAARTAYAAYGARGCNACN TTYAAYCCNACNGAYGAYYTNGTNYTNAAYGAYGGNAAYYTNTGGGAYGTNMGNTCNAAY AARATGATHTAYAARTTYGAYAARTTYAAYCAYTAYACNAGYGGNMGNTTYCAYCCNCAR GGNYTNGARGTNGTNATHAAYTCNGARATHTGGGAYATHMGNACNTTYMGNYTNMGNCAY ACNGTNCCNGTNYTNAGYCARTGYCARATHATGTTYAAYCAYAGYGGNGAYATHTTYTAY GCNATHCAYGTNGAYGAYGAYGCNAAY---GAYACNACNACNMGNMGNGAYTAYGCNTCN ACNYTNMGNTGYTTYGAYGCNYTNGAYTAYTCNAGYATHGGNGTNTTYGAYYTNAARGCN CAYAGYATHTTYGAYATHAGYATHCAYMGNGAYGGNATGYTNYTNGGNGTNATHGARCAR GARGCNGCNGGNGAY------------GARTCNTTYTGYMGNGTNTAYGARGTNGGNMGN ACNMGNGARCCNGARGAYCARGTNGARGAYGAYGAYGARAAYGCNCCNACNGAYGAYGAY GAYTTYGAYGAYGAYGAYGAYGAYGAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARGARTTYGAYMGNTTYTCNMGNAAYGARACNAAY GAYGARAAYAAYATGMGNACNCCNCCNAARATGMGNCCNGTNGCNCCNAAR------CCN TCNCARCCNACNACNTCNTAYGTNCCNYTNCCNMGNGTNAGYCCNAARMGNAARGARYTN AAYMGNCARGTNMGNCARATHYTNCCNAARTCNTTYGTNTTYGARACNAARAGYACNTCN CCNGCNAARGCNACNGCNMGNGTNYTNAARMGNAARGCNACNCAYTAYCARCARMGNAGY CCNYTNAARATHYTNCCNAARCCNACNCCNCCNTCNAGY------GTNMGNCCNAARYTN YTNTCNCAYTCNMGNATGTTYACNMGNTCNCARMGNAAYAARGCNAAYAARACNACNGAR YTNACNGTNGARGARGAYATHGARGARAAYAARGAYACNGARGARAGY------------ ------GARATGAGYGARGTNGARGAR--------------------------------- ---------------------------TCNGGNCARTCNCARGAYGARGAYCARATHCAR YTNGAYGAYYTNATGGCNGCNTGYACNACNATHAGYTAYGAYGCNAARMGNTCNGTNATH ACNGARGARAARAARAARAGYAARGCNCARAARAARAARAGYACNMGNYTNTCNYTNYTN AAYGCNGAYATHATHGAYACNGAYCCNAARAARGAYGARMGNGAYACNGCNTTYGCNCAR CAYTAYTTYAAYAARGTNAARGARGTNYTNCARTCNGAYCARGAYMGNTTYMGNACNTTY YTNTCNYTNYTNCAYGAYYTNAAYAARGAYCAYAGYAGYCCNGTNGARYTNTAYACNGAY ATGGTNTCNYTNYTNTCNGAYCAYCARGARYTNGTNGAYGAYTTYGCNGGNTTYYTNYTN TCNTTYCARGCNGTNGARTGYCARTGYTTYACNAAYTTYTGYCARTTYAAYCARATHMGN ACNTTYYTNMGNCARGTNGARATHCAYTGYGGNTCNTCN---TCNGGNTAYTAYCARAAR ATHYTNMGNACNATGTTYTCNTGGYTNACNYTNTGYCAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CCNGCNCCNTCNTCNGAYGAYMGNACNYTNMGNACNAARAAYMGNGTNMGNAARAARYTN ---CARMGNMGNATHAAYACNAAYGAYGGNTTYTAYCCNCCNGGNMGNTCNCARGCNGGN MGNMGNAAYMGN------GCNAAYGGNGAYCCNGGNYTNCAYGGNGAYATGGGNATGGTN CAYGGNCAYGAYAAYGGNCCNYTNGAYGTNGARGAYGARACNTCNYTNATH---CARTGY YTNTCNGCNYTNCCNYTNCCNAARGTNAGY------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGARCAYTAY GARYTNGTNCARGARATGCCNACNATHGARMGNATGACNACNCARGAYMGNYTNAARCAY GCNMGNAARMGNMGNAGYCARCARYTNAARMGNTTYGGNCARTAYGARAARCARYTNGAY AARGARAGYTCNAARAARAARAARAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY ATHTAYCCNYTNCCNCCNAARAARYTNTTYCARYTNGARGAYACNAARGAYTCNTCNGAY TCNGARACNAARYTNTCNYTNACNACNGAYACNGARGAYYTNMGNYTNCARAGYACNATH AGYGTNGAYCCNGARACNACNAARGAYTCNATHGCNTCNGAYTCNGCNCARGARGGNCCN ACNCCNGTNAARAARCCNAARATHAAYMGNGAR---------GGNGARGCNYTNGARGAR MGNGARMGNGTNTTYACNGCNGARTGYATHTTYGARTAYCARTGGCCNCARGAYGGNGGN GARTGGCAYATHYTNCARGARCAYGTNTGYGARTAYYTNAARATHAARTCNTTYAARMGN AARCAYCCNGAYYTNTAYMGNMGNACNTGYGAYAARGARGARAARGARTTYYTNMGNGAR MGNGGNGTNGTNTCNGARACNCARTCNGAYYTNGGNYTNACNGCNYTNMGNAGYGAYGAR GTNTAYGAYYTNATGYTNAARGAYTAYAAYGAYAARTAYCARGARTAYATHTCNGTNYTN CARGARMGNCARAARTCNGTNATHMGNGARAARCAYAARGARTAYGGNGTNGCNAARYTN GAYAARGCNAARATHGARTCNTAYAGYAARAARGCNGCNMGNGCNGCNGCNGARTTYAAY GCNAGYYTNATGMGNGARAARAARGAYGARMGNMGNGCNTAYTTYGAYYTNCARACNTAY ACNATHCAYCARTGYMGNCAYACNTAYMGNTCNYTNCCNCCNCAYYTNACNAARATGGGN GCNTAYCCNGTNGCNYTNATHCCNGGNCARTTYCARGAYCAYTAYMGNAARTAYACNGCN GARGARYTNMGNTAYTTYCCNATHAARACNTCNYTNGTNGAYCCNCCNAARCCNGTNMGN TAYCCNGCNAARATHCAYGGNYTNGARAARTGYMGNATHTGYAARYTNMGNTCNACNAAR GARGARMGNAARAARGAYMGNYTNGTNMGNTGYGCNCARTGYGGNAARATHGGNCAYATG AGYTGYYTNGAYYTNACNCCNGARYTNGTNGCNGTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GTNGAYATHYTNGGNACNTAYGARTCNYTNGARAAYAARCCNGARGCN GTNGTNMGNTGYCAYGTNGGNAARGGNCARGCNATHYTNTCNGGNGTNCAYYTNGARTTY CCNGCNAARTAYYTNGAYMGNGTNGAYACNGAYYTNGCNCCNYTNYTNCCNAAYTTYATH AARGCNGAYMGNCARMGNCAYTGYGCNTTYYTNGAYGTNYTNCARATGYTNGGNGTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARCCNGAYGCNCCN AARGCNACNACNTTYNNNTTYGGNNNNACNNNNACNNNNNNNNNNNNNNNNGGNTTYNNN TTYGGNNNNNNNACNNNNNNNTCNACNNNNNNNNNNNNNNNNNNN---------GGNNNN ACNTCNTCNACNCCNGGNTTYTCNTTYTCNAGYAARGCNGARACNAGYAARTCN---ACN GGNTTYGGNAARTCNACNTTYAGYTTYGGN---TCN------------ACNCCNTCNGAY ------------------GGNAAR---TTYTCNTTYGGNACNGCNCCNAGYGCNGCNGCN ---GARAAYAARTCNGARAARCARGARGGN---------GGNAAYGAYGAYGARGARTAY GTNCCNCCNAARCCNGARGTNAARTCNATHCARGARAAYGAYGCNYTNTAYTCNAARMGN TGYAARYTNTTYTAYCARAARGAYGAYAARTGGGTNGAYMGNGGNGTNGGNACNTTYCAY YTNAARCCNATHAARGAYACNAARACNCARATHYTNGTNMGNGCNGAYACNAAYYTNGGN AAYATHYTNYTNAAYGTNATGYTNTCNTCNAGYATGCCNGCNTCNMGNCARGGNAARAAY AAYGTNYTNYTNGTNTGYATHCCNAAYCCNCCNATHAAYAARGCNGARGGNGGNAGYGAR GARACNAARGTNCCNATHCCNATGYTNGTNMGNGTNAARACNGGNGARGAYGCNGAYGAR YTNYTNGCNAAYATHGAYGARMGNAARGCNATHYTNMGNCCNTCNGAYTGGTTYTCNCAY GGNGAYGCNCCNGAYGCNAARCCNGARGCNMGNYTNMGNTCNGAYGCNGCNAARGARAAY GCNATHAARAAYMGNGGNACNGTNAGYGARTCNATGGGNGGNTAYTTYGAYCCNCCNCCN GARMGNACNGTNCAYCCNMGNGCNGTNMGNCCNGARGCNGARGCNAAYGCNGTNGGNGAR MGNGGNGGNGCNATGMGNAGYYTNATHGAYAAYTAYGGNAAYYTNGARGTNTCNCCNMGN CCNGGNCCNAARGTNYTNGGNTCNGARGCNGARGARTAYAARYTNMGNGARCARGGNAGY ACNAARTTYYTNYTNAAYCARTAYAGYACNCARCCNATHCCNCCNCARGARCARCCNCCN CARCCNMGNYTNGGNYTNGGNGGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GGN GTNTAYGTNAARMGNCARATHCCNAARATGACNATHGGNGARTTYTTYGGNGCNACNGAR GGNACNACNATGYTNGTNAAYATHGCNAAYAARCARGGNGCNATHGGNMGNYTNTCNCCN YTNYTNTTYYTNGAYCCNGAYAARAARGARYTNGTNAARTTYGAYTAYGTNACNGCNGAR CCNYTNMGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ACNTAYTGGGCNTTYGCNGAYTCNTAYACNTGYGAYTGGTCNGTN YTNTGGACNGCNMGNGCNGTNGTNATHACNTCNTGGATHGTNTTYATHATGTTYTTYYTN TCNYTNATHATHTTYGAYCCNYTNGGNTCNATHGARCAYMGNCAYGCNGTNCARTGYCAY GTNAGYAGYACNGGNGARGARCAYATHTCNATHGGNAAYATGTCNGCNCAYAARGTNTGG GARGCNMGNTGYMGNYTNYTNTGYTGYTGYATHCCNAARAGYTGGATGACNYTNGCNAAY ATGGCNCAYTAYATGAARTAYGCNATGGGNAGYTAYGGNTGGCCNTTYTAYATGTAYGAR TAYYTNGCNACNGGNATGTGYMGNYTNTGYTCNMGNTGYMGNTGYTGYTCNTGYATHMGN ATHGGNAAYGAYGTNGTNGAYGAYAAYTCNTGYCARTGYCAYACNGCNGCNATHMGNAAR YTNACNGGNATHGAYGARGAYGAYYTNGTNTAYGTNACNTTYCAYAAYAARTAYAARGAR ATHCCNTTYTAYGTNGCNGTNGAYMGNGAYCARAAYGCNGTNGTNGTNAGYATHMGNGGN ACNYTNTCNYTNCARGAYGCNYTNACNGAYATHTCNGCNCARGGNACNCCNYTNGAYATH CCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNYTNCAYAARAARAARYTNGARGARAARGTNYTNAARTCNTGG TTYGGNGTNATHCARACNMGNTGGMGNCAYMGNYTNGARMGNAARTGYCARGARAARGCN CARGCNGTNTGYYTNCARYTNACNAAYGAYTAYGARGCNAARATHACNTCNYTNAAYGAR ATHATHCARCARYTNGARTCNAARGTNAAYGCNYTNCARTCNGARMGNGARCAYTAYATG GAYCARGTNAARAARGCNTTYATGMGNGGNGTNTGYGCNYTNAAYAAYGARGCNATGTCN GCNTTYGGNCARCAYCARGCNGTNCARGARGAYAGYGARYTNTTYTTYCCNACNACNTCN ACNTTYGAYACNATGTCNYTNTCNGARCCNGGNACNCAYAARCCNACNAGYTTYGAYTTY TAYGAYAARGAYYTNATHCARACNAARTCNYTNCCNGCNGAYYTNACNTCNACN------ ---------------------------------AGYMGNAARAAYGARYTNCCNGTNCCN CARYTNGCNGAYCARTAYATHGCNGCNACNGTNAARCCNAARTCNTCNAARGCNAAR--- ---------------------------CCNACNAGYTCNAARTCNACNTCNMGNTCNGGN GTNCARCCNCARAGYGGNCARGTNYTNGCNCCNCCNATGGCNTCNATHGTNGTNGARAAR CAYCARCCNGTNACNAARCARACNATHGGNAARGCNACNGCNTCNMGNTAYCCNAARATG GGNMGNAARAARATHCARATHGCNMGNATHAAYGAYGARMGNAAYMGNCARGTNACNTTY ACNAARMGNAARTTYGGNYTNATGAARAARGCNTAYGARYTNAGYGTNYTNTGYGAYTGY GARATHGCNYTNATHATHTTYACNAGYAAYAAYAARYTNTAYCARTAYGCNAGYTCNGAY ATGGAYAARGTNYTNYTNAARTAYACNGARTAYAAYGAYTCNGTNGTNAGYCARACNAAY AARGAYATHATGGARATGYTNAAYAARAARGARAGYAARGGNGGNGAYCCNGAYGGNGAY GAYGAYGARTAYCCNATHNNNCCNMGNACNGAYGAYCAYTAYMGNAARATHGAYGCNGAR TTYGCNAARGCNATGAAYGAYGGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGAAYGGN GGNGARTGYTAYAARTGYGGNMGNGCNGGNCAYTGGGCNMGNGAYTGYCARAGYGGNGCN GGNGGNGGNGGNMGNATGAGYMGNGAYMGNGGNGGNCCNAGYMGNGAYTTYMGN------ ------AGYGAYAARTGYTAYAARTGYAAYMGNCCNGGNCAYTTYGCNMGNGAYTGYMGN GTNGAYCARGAYMGNTGYTAYAARTGYAAYCARYTNGGNCAYATHGCNMGNGARTGYGAY AARCCNATHGAY---TCNGGNGCNTGYTAYAAYTGYCARGGNACNGGNCAYGTNCARMGN GAYTGYCCNGARGCNTGYAAYAARCCNTGYTAYMGNTGYGGNGARCCNGGNCAYGTNGTN AARGAYTGYCCNGAYGAYMGNGGN------------GTN------------GAYGAYMGN AARTGYTAYGGNTGYGGNGGNATHGGNCAYATHTCNMGNGARTGYCCNACNGCNCARMGN AGYAAYTCNAARGARTGYTAYMGNTGYGGNNNNNNNGGNCAYYTNCARAARGAYTGYCCN TCNAAY---AARACNCAR---CARTGYTAYACNTGYAAYGARATHGGNCAYATGGCNMGN GAYTGYCCNACNGARTAYYTNMGNGCNAAYCCNCAYGARAARCAYATGGCNYTNCARGAY ACNAARGAYTAYACNACNCAYTCNYTNGCNAGYGTNGCNTAYCARATHAAYAGYYTNGCN ACNAAYTTYYTNAARYTNYTNGAYYTNCARCARGGNCARYTNACNGAYATGGARTCNAGY GTNAAYCAYYTNAGYCARATHGTNACNATHCAYAARGARMGNGTNGCNMGNMGNGARATH GGNGTNYTNACNTCNAGYMGNAAYGTNCCNMGNCCNTAYGGNGTNAARAAYGGNATHATH TAYCCNAARCARACNGARMGNCCNATHAARTAYACNMGNACNCCNATHGAYTAYAAYGTN YTNGAYGAYATHGGNCAYGGNGTNMGNACNAAYAAYCCNCCNCARGCNACNCCNAARACN GCNMGNAGYCCNTCNATHAGYAGYAAYCAYAGYAGYAAYAGYATGACNGCNAAYCARGCN CCNACNACNAARCCNCCNACNCCNCCNGTNTAYMGNGCNAGYTCNGGNGGNACNATHGGN AARGGNGCNGGNGGNATHTAYMGNTCNYTNACNCARCCNATHATHCCNCCNGTNGCNCCN CARATHACNGCNCARGGNAAYTAYCARGGNTAYAAYCARTCNGGNCCNGCNTCNCCNCCN YTNCCNCCNCCNCCNAAYAAYGAYCCNGTNGAYCARTTYAAYTAY---ATHAGYGCNCCN CCNATHAARTTYAGYGAY---------GGNCCNCCNAGYGCN---------ATGCAYGCN AAYATHTCNGTNGAYAAY---GCNATGGGNGARAAYGCNAAYGGNGARACNTAYGCNGAR ACNGGNCCNCARYTNYTNCARGCNCCNGCNTGGATHCCNAARCAYTAYYTNGARAARGTN GTNGCNATHTAYGAYTAYCCNGCNAAYAARGCNGAYGARYTNTCNTTYTCNGARAAYGCN GTNATHTAYGTNATHCAYAARAAYGAYGAYGGNTGGTGGGARGGNGTNATGGAYGGNCAR ACNGGNYTNTTYCCNTTYAAYTAYGTNGARCCNTGYATG---------YTNATHATHACN GCNGAYGAYTTYGGNTTYAGYGCNGARMGNAAYAARGGNATHAARGARGCNGCNCARAAR GGNATHGCNACNAGYGCNTCNATHYTNYTNAAYTGYACNGGNACNAARGARGCNATHCAR TTYGGNAARTCNGGNGCNGTNTGYCCNGGNYTNCAYYTNAAYYTNACNGARGGNCARCCN ATHTGYCCNGAYATHTTYCARACNYTNACNACNGARGGNGGNATHTTYMGNGGNAARGAY GGNACNMGNMGNGCNYTNGARGCNGGNGARATHGAYYTNAAYGARGTNAARAARGARATH GAYAGYCARATHGARMGNTAYGARGARYTNTAYGGNGARAARCCNGTNTAYGTNGAYGGN CAYCARCAYATHCAYYTNCAYACNGAYGTNATGCARATHTTYGCNAARAGYYTNGARAGY CAYGGNATHAARGTNNNNNNNNNNCCNAARGAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNATHMGNTCNATHCAYTCN TTYGARGARAARATGAARATGATHGTNTCNCCNAGYGAYGARAAYGAYGARATHGAYATH CARTAYATHATGACNMGNGAYGARGAYMGNGGNGARCCNATHCAYYTNYTNAARACNGCN CCNAAYGAYGGNTAYATHGGNAARATHMGNAARMGNYTNCARGARGAYGCNGCNGCNMGN GARGARMGNGARAARMGNMGNMGNAARGTNYTNGGNGAYCARATGATGGCNCAYCARGCN CARGARGARGCNMGNMGNGARGARATGATGGTNAAYMGNYTNATGMGNCARTCNCARCAR GARMGNMGNATHGCNGTNCARYTNYTNCARGCNMGNCAYGARAARGARATHATHMGNCAR AAYMGNATHACNMGNGARAARCARTAYCARGARMGNMGNYTNAARGAYTTYGARGAYGCN YTNGAYYTNGARGCNGARYTNGCNGCNYTNCAYAARATGGARTAYGCNGARCARATHAAR GCNGAYCARGARYTNCAYGAYCAYATHGCNACNCARMGNGCNGARGARMGNTAYAARMGN CAYTAYGAYATGAGYTCNGARATGGTNGCNAGYATHGTNGAYTTYGCNTGYAARGTNGCN GARTAYMGNGARYTNACNAAYAAYYTNYTNCCNGCNAARYTNATGMGNGAYTGGAARYTN YTNTTYACNTCNGGNCARCCNYTNTAYGARCARACNGARCCNGARATHACNGARYTNACN CCNGARCARGTNYTNGARGARGAYMGNCARCARYTNYTNGAYGARGGNGAYTTYACNGAR TAYAARACNATGTCNGGNGARTGGAARCCNCCNGARGAYAGYGARATHGCNGGNCCNCCN MGNGAYAAYCCNGTNGTNCCNCCNACNCCNCCNCCNCCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARGCNGARTTYYTNACNTTYGARGAYTTYGAR ATHMGNTTYAARGARTAYTGYMGNTGYAAYAAYTTYYTNTTYGTNAARMGNTCNTCNGAR GCNATHAAR------GAYGARGCNYTNTCNCAYYTNMGNTAYGARCAYATHGCNTTYGGN TGYAARCARGGNGARAARMGNCAYGARACNGCNGGNACNGGNATHMGNCCNMGNCARMGN ACNTTYAARGTNGGNTGYCCNGCNMGNGTNAARGTNGTNMGNCCNAARGAYAARGGNMGN CCNTAYYTNAARATGACNGTNTTYAAYGCNGARCAYAGYGGNCAYCARGTNAAYAARGAY GTNTGYCARYTNTAYCCNGARAAYMGNMGNYTNGTN---YTNGAYGARACNTCNCARGTN ATHGCNTCNTCNACNACNATHGCNGARYTNAARGCNATGYTNGARAARMGNCAYAAYCAR CCNYTNATGAGYCARGAYATHTAYAAY---------------ATGTCNYTNYTNGCNGCN MGNYTNGGNCCNGTNGCNYTNTCNGTNYTNMGNAARAAYCCNATHAARCAYYTNCARAAR ACNAGYGTNMGNAAYGCNGGNACNATGTAYMGNTCNACNGTN------TTY------CAR GARCCNAARGTNATHCAYTAYGCNGGNACNGCNATHAGYGCNTTYATGTGGTAYTGGATH YTNTAYCAYTGYTAYTTYGARTTYGAYCAYYTNGTN------------------------ ------------------AARATGCCNGCNGARAAR------AARYTNATHGARAARYTN GGNGAYATHCCNGTNGTNTCNGAYGGNTGGTGYGCNGCNTGGGAYGTNTAYAAYAARGTN AARGARTAYAAYTCNYTNACNMGNATHACNYTNCARGTNGCNGARACNAGYGTNAARAAR GCNGGNGARATHTCNGCNCCNATHGTNAAYAARTAYCARCCNCARATHGAYAAYATHAAY AARTTYGCNTGYGARAARYTNGAYACNYTNGARGARAARTAYCCNATHATHCARCARCCN TCNAGYGARGTNCARGARGCNTGYGTNAAYTAYGTNAARCCNGTNGTNGGNTAYGTNAAR CCNGTNGTNTCNCARGTNCARGTNATHTAYGGNAAYGGNAARAARCARGTNAAYAAYGTN AARACNMGNGGNACNAAYTTYGTNAAYGGNGCNAARGAYYTNAGYATHGAYACNGCNTCN AARGCNGTNAAYGCNACNTTYAAYACNCCNCCNGGNMGNYTNGTNACNAGYACNYTNGAY GGNGCNYTNAAYATGGCNGAYAAYATHGTNGAYAARTAYYTNCCNGARGARAARGARGAY TCNGARAARGARGAYGTNGARGARGAYGARGAYGTNCCNATHGAYGAYGGNGARAAYGCN AAYGARGGNACNGAR------CARATGGARGTNATGGARCCNTCNCCNCARMGNGTNYTN GTNCAYTTYMGNTCNGTNAGYGAYAARGTNMGNCARMGNATGTAYAAYMGNGCNATGAAR GAYTTYMGNACNGCNAARAARCAYAGYYTNGAYACNYTNAARMGNATGCARGAYACNGTN AAYYTNATHGARTAYGCNAARACNAAYYTNGAYGGNGCNAARAAYAARGTNGARCAYATH TGGAGYGARATHAARAAYGARAAYCCNTCNGARAARGARGARAAYATGAAYTCNGAR--- ACNACNAGYAARATHGARGARMGNATHATHCAYYTNGGNAARACNYTNGCNYTNCARATH MGNAGYACNTCNTCNGCNATGGARAGYGCNGCNTCNGARATGGGNCARTTYGTNMGNCAY CCNATHAGYAARTCNAARGARTAYACNGARYTNYTNAAYAGYTTYTCNTCNGTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNATGTGGTAYYTNATGGARAARTCNCARGAY AARTAYTGGYTNTCNGAYMGNYTNATHMGNGCNATHGGNMGNTGGAARYTNTTYGAYAGY GAYGARAARATHGAYTCNYTNATHGARTCNGGNGCNGAYGTNAAYMGNMGNCAYGGNACN YTNYTNCCNYTNCAYTAYGCNAGYTGGGTNGGNGAYGCNCAYGTNYTNAARCAYYTNATH YTNMGNGGNGCNMGNGTNAAYGARCARGAYGGNTAYCARMGNACNGCNYTNCAYTAYGCN GCNGARCARAAYGCNGARTGYGTNCARGTNYTNYTNCARAAYGGNGCNAAYATHAAYCAR GGNGAYGGNAAYYTNGAYAARGCNYTNCAYTGGGCNTCNTAYAARAAYAAYGTNACNAGY GTNAARGTNYTNYTNCARGCNGGNGCNGAYGTNAAYGCNGTNGAYYTNAAYATGGAYACN CCNATHAGYTGGGCNGCNMGNAARGGNAAYYTNGARGTNGTNAARYTNYTNYTNGAYTAY AAYGCNGAYGTNGAYATHCCNAAYGTNGCNGGNAARACNGCNYTNCARMGNTCNGCNTGG ATHCARGCNAGYGGNYTNAAYACNGTNCARGAYGAYMGNACNATHAARYTNYTNATHAAR GCNTCNGGNCARTTYAAYYTNYTNGAYACNAARGGNGARCCNYTNCCNMGNATH------ TAYATHMGNYTNGGNCAYTTYYTNAAYCCNYTNGTNTAYAAYCCNMGNTCNYTNYTNGCN CARTGYMGNMGNCARATHMGNMGNTGYATGGGNCARAGYTAYYTNCCNTCNACNATHCCN CAYYTNCCNYTNCCNGCNCARYTNCARGARTTYYTNYTNYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGATHGARGTNAAYYTNGCNGCN YTNGTNCARGGNACNCARYTNGCNCARGCNCAYATGMGNAARGAYAARGGNGGNAARGGN GGNMGNATHATHAAYATHAGYTCNATHGCNGGNYTNYTNGAYTCNTTYACNATGCCNATH TAYTGYAGYACNAARCAYGCNGTNMGNAGYTTYACNATHGGNATGGCNGGNCARCCNAAY YTN---GARTCNCARGGNATHGARTAYGCNGTNYTNTGYCCNGAYCCNGCNGAYACNGAR YTNATG---AARYTNGAYAARTCNAARATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGNTCNGGN GAYTAYTGYACNAGYGAYTCNCARTGYAAYGGNGAYGARTGYTGYCARATHATGAGYGAR TTYYTNATHGCNAGYAARMGNAAYGTNTTYYTNCCNACNACNGCN------------MGN ATGMGNATHGGNTCNTGYCARATGTAYAARAARGARGGNGCNTAYTGYAGYACNATHGAY AARATGAAYGGNTAYTGYAGYTGYGGNCCNGGNYTNTAYTGYCAYATGMGNGARGTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ACNGCNCAYTTYGTNTCNAARGAYTTYAGYGTNATHGTN GARAAYGGNYTNGGNATHMGNYTNCAYGTNATGYTNCARTAYTTYYTNGTNCCNGAYCAR YTNGARACNYTNTAYAARAARTTYAAYATGGAYTAYAAYAGYGTNYTNYTNMGNGTNATH GARAGYACNGTNAARAAYACNGCNATHTAYTAYCCNYTNGAYACNTTYMGNYTNGGNMGN AGYYTNATHGCNGARGCNATHTAYAARGCNYTNAARGARMGNYTNGARGGNAAYTGYTGY GAYGCNTGYTGYCCNAGYAGYTGYCAYAGYAGY---TCNAGYMGNTGYCAYCCNCCNCAR TGYGTNCCNGGNGAYTCNTGYAARGARGGNTAYCAYGTNGARYTNMGNTAYTTYCARYTN GGNMGNGTNGTNATHCCNGAYGAYGTNATGGGNMGNTAYATGMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNTCNGCN GARGARCCNCCNTCNTGYTCNTGGCCNCCNGGNATGMGNTGYGARCCNGCNMGNGCNAAR ACNATHAARATHYTNMGNTGGMGNTGYAARGARGTNAAR--------------------- ---------------------------TGYGTNCARGGNGTNAGYGCNGGN------GAY TAYACNGGNATGYTNGCNGCNGGNTGYGTNAGYGGNTTYTTYYTNGTNATGYTNGTNGCN TTYYTNATHATHGCNGTNAAYTGGGAYAARTGGTTYGGNGARMGNATGMGNGCNGARGGN AARTCNAARGCNCCNAARTCNTAYYTNAARAARAARAARGARGCNAARATGMGNYTNGCN CARCARTCNAAYGGNTAYAGYTCNAARTCNAARYTNAAYGGNACNATGCCNATGCARTCN ---GAYATHGGN------------------YTNTGGGTNCARCAYATGGGNCARCCNAAR GAYACNATHTAYGAYTAYTAYGARGARAARGARCARGGNATHACNATGGAYCCNGARAAY GARGARGTNTTYCARATHGARACNGARYTNGTNGAYAAYGARGTNYTNGAYGTNGGNCCN TAYAARTCNGCN---CAR---TCNGAYGCNAARCCNACNCAYGGNGAYATHTAYCCNGAR CCNTAYATHTAYACN---------------CCNACNATHAARGCNACNAAYTCN------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GTNGTNAAYAAYAGY TCNAGYTCNMGNCARGAYTAYGTNGARAARTGYAARAARYTNGGNTTYCCNGCNCARYTN GAYGARATHGTNTGYACNGCNTAYATHGCNGCNCARTAYYTNAARAARGCNAAYTTYAAR GAYAARGTNTAYYTNGTNGGNMGNGCNGAYGCNYTNGGNACNGARYTNGAYYTNGTNGGN ATHMGNCAYATHGGNGCNGGNCCNGAYCCNYTNAGYGTN---GAYGTNAARGAYTGGYTN GTNACNGAYYTNGAYCCNGARGTNGGNGCNGTNGTNGTNGGNTTYGAYCCNTAYATHAGY TAYCCNAARATHYTNAARGCNGCNAGYTAYYTNMGNAAYCCNGAYTGYYTNTTYGTNGCN ACNAAYGARGAYMGNTGYYTNCCNACNAARGGNGARGTNGTNGTNCCNGGNACNGGNTGY GTNGTNGCNCCNATHAARYTNGCNTGYAAYMGNACNCCNACNGTNGTNGGNAARCCNTCN TCNGAYATGTTYGAYATHYTNCARGARGTNCAYACNYTNGAYAARACNMGNACNATHATG GTNGGNGAYAGYYTNAAYACNGAYATHGTNTTYGCNAARYTNTGYGGNYTNMGNTCNYTN YTNGTNYTNTCNGGNAAYGCNAGYYTNAARGAYACNAARGGNYTNCCNGCNGAYAARATG CCNGAYGTNTAYGCNCCNTCNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNGGNGCNATGTGGAAYGAYMGNAARMGNCARGGN------GGNAAYMGN AAYATGGAYGARAARMGNMGNMGNMGNGAYTCNTCNGGNTGGGGNGAYMGNGAYMGNTCN ------MGNGGNAGYCAYMGNAGYGGNGARGGNMGNGAYMGNAAYMGNCARTCNMGNTGG GARACNGARAARGAR---TCNGTNGGNGARGAYGAYTAYGAYCCNGCNGARCCNACNGAR GARGARGAR------GGNAAYMGNAAYCARGAY---TCNAAYYTNTAYTGYCAYGTNTGY AAYATHTCNGTNTAYGAYGAYGARAGYTTYCARMGNCAYYTNAAYGGNGTNAARCAYAAR ACNMGNATGGGNAGYATHYTNACNGCNCAYCARATGAARTCNAAYCARYTNAARTCNMGN YTNAARGCNGARGARCAYYTNMGNAARATHGARMGNAARGGNGGNMGNGAYCCNGAYTAY TTYTGYAARATHTGYAAYAAYGAYYTNACNATHCCNTGGGARMGNCAYMGNTAYTCNAAY ATHCAYAARCARMGNYTNYTNCARGTNMGNAARGGNTGYGGNTGGTGYAAYGTNCAYGAY TTYACNAAYTTYTCNGARGTNYTNGARCAYMGNGARACNGAYGARCAYAARAARAAYGCN GAYYTNTAYGGNAARAARGARGAYGARAAR------------------------GAYMGN GAYMGNTCNMGNAGYMGNAGY--------------------------------------- ------MGNGARMGNAARGARATHAARGARGARGAYYTNACNATHCCNGARTAYGAYGCN GARATHCCNGTNGGNYTNAAYTAYGTNATHCCNGTNACNGGNTTYTTYTGYAARYTNTGY CAYAARTTYTAYAAYGARAARTCNGCNAARGGNGCNCAYTGYCARAGYGARGCNCAYTAY GARAARTTYAARGCNGCNATHGARGCNAARATHGCNGCNMGNGARAARCARAARGARGAR GARGCNGCNGCNGCNGCNGCNGCNGARGARGAR------------GARATGYTNMGNGAR GARGGNGARGAYGARAARGAYATHGCNGARGAYGAYGARGCNAAYGAYATHGARAARAAY GTNGGNGAYGAYGAYGAYGARAARYTNGAYGAYGAYCARGAYGARGAYGARYTNATGGAY ------------------------------------ACNAARGAYGAYAARYTNATHGAR GAYGTNGTNYTNAGYGARGAYGARACNAARCARGAYGAYGCNCCNGAR------GCNTTY YTNAAYGAYGCNGAYGCNAGYTCNATHYTNAAYTTYATGGCNGARGAYGGNGARGARGCN GTNGARCAYTGGCAYCAYATHCARMGNMGNATHGCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GGNGGNTGGYTNYTNTAYAARTAYATH TGGMGNAARATHYTNGARATHMGNGARGARGARGAYAARCARTAYTTYATHCAYYTNMGN MGNCARCAYCAYTTYGAYAGYAAYCARMGNACNTGYAAYATGACNGTNYTNTCNATGATH CCNAAYATHMGNAARGTNYTNATGAARAAYYTNGAYACNGARAGYGTNAARGARATGYTN AARTCNAGYCCNCCNAAYAARYTNGAYYTNTGGGARGAYYTNAARATHATGAGYATGACN MGNACNATHGCNGCNGTNTAYGGNACNTGYATGYTNTCNGTNATGYTNMGNGTNCARYTN AAYYTNATHAGYGGNTAYATHTAYYTNAGYAGYATHCAYGCNAARAAYCCNGARAARACN AARACNAAYCAYTGYACNTCNATHCCNCARMGNGTNAARGARMGNTAYYTNTCNYTNATG AAYGARTTYYTNGARCARGGNYTNYTNGAYTTYGTNAGYTTYYTNAARYTNGCNGTNAGY AARGARATHGGNAGYYTNTCNYTNMGNGARCARYTNAAYYTNGARAAYGTNACNGCNGTN TTYGCNCAYGTNMGNGARMGNGTNGARTGYGGNGTNGAYMGNCCNACNGAYTCNYTNCAY CCNTTYYTNYTNAARGGNGARTGYYTNCCNGAYGAYGTNTCNTCNGTNGTNATHAGYACN GARGAYGARYTNYTNGARAARYTNATHGGNGARACNMGNGAYATHGTNGARAGYAAYGAY TTYCAYACNGTNYTNAARGARAGYATHGAYMGNGGNTTYCAYTGYYTNYTNGAYGGNATG GCNGARCAYTAYAARAARATGAAYACNTCN------------GCNGGNGTNCAYGAYAAY TCNYTNGTNGTNGCNAARYTNATHCCNGTNGTNAAYTCNYTNYTNGTNMGNATHTGYGGN GAYGCNCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------GAYTCNTCNCCNCARAAYAARGAYCCNACNYTNAAR AAYAAYATHTGGACNMGNATHTCNAARGARATGGGNGAYGARMGNACNACNGGNGARGAY TGGAARAARATHTGGAARCARAARMGNGAYGCNTTYATGAARAARMGNMGNGARATHCAR AAYAAYGGNCCNGCNGCNAARACNACNTCNAARATGCCNYTNTAYGARCARYTNAGYTTY YTNGAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGGCNCARTAYATHCARGTNGTNGARGAYGARAAYGAYGARACNATH GARATHCCNAGYGARAAYGAYGGNACNYTNYTNYTNACNACNYTNGCNGCNCARTTYCCN GGNGCNTGYGGNYTNAARTAYMGNAAYCCNGAYACNGGNGCNTAYMGNGGNATHMGNYTN TCNGAYGGNGTNYTNCAYCCNCCNGARGGNYTNTGGGARACNCAYMGNTAYGTNGCNGTN TTYCCNAARGARAAYAARMGNAARGGNGARGARGGNTTYGAYAAYCCNGCNGCNAARACN AARMGNGTNGARAAYCAYAARTGYTCNGAYYTNATHGTNYTNGGNYTNCCNTGGAARAGY ACNGARGAYGAYYTNACNAARTAYTTYTCNCARTTYGGNGARYTNGTNYTNGTNCARGTN AARMGNGAYCCNAARAGYGGNCARTCNAARGGNTTYGGNTTYATHMGNTTYGTNAAYTAY GARTCNCARGTNAARTGYTGYGCNCARMGNCAYATGATHGAYGGNMGNTGGTGYGAYGTN ACNATHCCNAAYTCNAARCARTCNAGYAAYTCNMGNAAYCARGGNTAYGAYTTYTCNCCN TAYGTNCARGGNGGNAAYGGNTAYGAY------GAYCARCARTAYGARGAYCARGGNAGY GARCARGARGGNAAYAAYCARATGATGAAYMGNAARGTNTTYATHGGNMGNGTNACNGAR GAYATHACNGCNGARGAYYTNMGNAAYTAYTTYTGYAARCAYGGNGARGTNGTNGAYGTN TTYATHCCNAARCCNTAYMGNGCNTTYGCNTTYGTNACNTTYGCNGAYGCNGAYACNGCN CARTGYYTNTGYGGNGARGAYCAYATHATHAARGGNGCNAGYGTNCAYGTNAGYAGYGCN ACNCCNAAR---TCNTTYGAYAARAGYGGNGARMGNAARGGNTTYAGYCARCARAGYTAY AAYCARGGNGGNTGGAGYCARAAYMGNGGN------GCNCCNGGNCCNGTNGGNGGNGGN GCNAAYGGNGCNGARGGNGGNATGGCNGCNAAYAAYYTNGGNATGAAYYTNYTNAAYTCN GCNATGYTNGCNGCNGCNCARGCNATGYTNCARAAYCCNCARGGNTGGGGNGGNYTNAAY CARGGNAGYCARGGNGGNAGYGGNGGNAAYATGGGNGGNGGNGAYCAYCCNCCNCCNATG ACNCCNATHTCNAAYCARGGNGGNTTYGGNAGYATGGGNGGNGGNAGYGCNAGYGGNACN GGNAGYGGNAAYTGGTGGACNAAYGARAGYACNACNACNGGNGGNGGNCAYTAYGGNGGN TGGGGNGGNTCNCAYGGNGGNMGNGGNAGYGGNGGNTGGAGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CCNGAYGTNGARMGNGTNMGNMGNGCNCAYYTNAAYGAYYTNGARAAYATHGTNCCN TTYGTNYTNATHGGNYTNYTNTAYTGYGCNACNGGNCCNAGYATGAGYACNGCNYTNYTN YTNTTYMGNATHTTYACNGGNGCNMGNATHYTNCAYTCNATHGTNTAYGTNTTYAARGTN CCNCARCCNGCNMGNGCNYTNGTNTTYTTYGCNGGNGTNATHGTNAAYGCNATHATGGCN GTNCARGTNATHAARAGYGCNGCNTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARAARTCNAAYTTYAAR TCNATHGTNTAYATHGCNGCNGTNACNCARAAYGARTCNGAYGGNATHAAYYTNGTNGCN GTNACNGARACNGGNGTNMGNYTNTAYTTYACNACNTCNCCNTTYAARCARGTNAAYMGN MGNCCNAAYACNYTNGCNYTNGTNCAYGTNMGNYTNCCNCCNGGNTTYTCNGCNACNAGY ACNCAY---CAYCCNCARMGNGTNCAYACNGCNTTYCAYAGYMGNGGNACNYTNYTNYTN YTNGARAGYGARAAYCARGAYAAYAAYGTNYTNTGGTCNGTNAGYTGYGAYTCNTTYCCN TTYCARAARCARYTNATGGARGCNCAYACNAARGTNGCNGTNGAYGGNAARACNTGGGCN GTNAGYGARATHYTNCCNGCNTCNAAYGAYTCNAGYATGCCNTCNAARYTNGCNAGYMGN TCNCCNACNGAYCCNCCNAGYGTNGTNACNCARCAYGCNGTNCCNCCNMGNMGNTTYATH ATHYTNAGYGCNCARGGNATHCAYATHTTYCARAARYTNMGNCCNGTNGARCARYTNMGN CARYTNATGATHGARTGYGGNGGNCAYGARGCNGARCCNGTNAARTCNTTYTTYMGNYTN CAYAARATHGAYCARGCNTGYGCNTCNTGYYTNGTNYTNGCNTGYTCNMGNGCNCCNGCN GAYGARCARGTNTCNCAYTGGGCNMGNATGGCNTTYTTYACNTAYGGNGGNGARGCNCAR TAYAAYTAYAGYGGNATGMGNCCNTTYAAYGCNGGNCCNGGNCARATGACNAAYTCNGTN ATGTAYAAYCCNAAYTTYATGCCNATGTCNGCNGCNCARGTNTCNCCNATHCAYGCNTCN ACNCCNCARGTNCCNGCNTCNATGAAYYTNACNGCNCCNATGGGNCCNGGNTCNAAYCCN ATGCAYGARGTNATHTAYTCNGGNAARCAYAAYGGNATHTAYATHTTYYTNAGYMGNATH YTNMGNCCNTTYTGGGAYAGYTAYGTNGCNACNGARYTNGTNTGYAAYACNAARMGNGGN CARGTNGCNTAYYTNACNAGYAGYTTYAGYGTNGARGARYTNTGYATGGCNYTNGARYTN ACNMGNGAYYTNTCNGCNTTYGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CARGGNTAYTTYMGNCCNGGNATHCARCAYACN TGYGGNTGYMGNYTNTCNGAYCCNGGNAAYCCNCCNGGNMGNCCNGTNTGGCAYCCNATH GGNGAYAAYGGNCARACNCARGTNGAYCARGGNAGYGCNACNGARCCNGCNGAYAGYGAY CCNAGYCCNAARTTYYTNTGYAARGCNCARACNGTNYTNGCNGAYGAYAGYCCNGGNATH TCNTTYCCNTTYGCNTAYGGNCCNTCNACNGTNACNATHCARGCNGARGAY--------- ---AGYTAYGAYYTNTGYCCNTCNAAYACNAARAAYCCNATHTGYACNGTNCCNATHAAY GAYGTNAGYCCNGCNCCNACNTCNACNYTNCARATGAGYCARGARGGNAGYTTYTAYGTN ---------------------------------CAYGCNTTYTCNCCNTCNATHCCNGGN ACNYTNTCNGTNACNTGYGTNGTNAAYAAYGCNATHTTYGGNAGYATGACNTCNCARGCN ACNMGNCAYATHCARGTNMGNGARCCNCCNAARGARGCNCCN---------GTNGTNAAR AARGGNCAYGCNGAYATHGAYCCNGGNAARAARGTNACNYTNAGYGARGGNAAYGCNACN CARTTYGTNTGYCAYGTNAARGGNGGNTAYCCNGTNGTN---TCNGAYGTNACNTTYMGN TGYGGN------------------------------------------------------ ------------------------------------------------------------ GTNAARGAYTTYCAYATHCCNGTNACNGTNACNCARGGNMGNACNAARGTNMGNGARYTN TTYYTNAARAAYAARCAYGTNACNGAYGTNMGNGCNATHGAYYTNYTNGTNATHAARGGN CARATGGAYYTNGTNGARACNGCNAAYATHTGGAARCARMGNAAYCAYATHATGATGTTY TTYCARGAYACNGCNAAYCCNAARCCNAARGAYTTYYTNTCNAARTTYTAYGARGGNCAR GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY CCNGARYTNGARCAYAARTCNAARAARGTNTCNGARAARGTNTCNGARACNGTNAAYGTN ATHGCNAAYGARCCNTCNYTNGCNTTYTTYMGNATHCARGARCAYGTNMGNAARACNYTN CCNCARYTNGTNGAYCARAARCAYGARGTNGARGARGTNCAYGCNATGGTNCARGGNGCN TGYTTYGAYGCNGARTAYGCNACNAAYGCNGTNAARGCNATGCARTCNAGYGCNATHCAY TTYCARAAYATHCARGAYYTNYTNAARAAYGCNYTNTTYATGAARCARCARATHACNTAY GARGARAAYMGNAARAARCARGGNYTNGCNGGNCCNTCN--------------------- ------------------------------------------------------------ ---------------GGNTTYTTYCAYMGNAGYYTNAARACNCAYGAYCARTAYYTNTGY GARGARCARCARCARTGYCCNGTNAARGAYGGNATHGGNMGNATHTGYCARTGGTGYMGN TAYGCNAARTGYATHGAYGTNGGNATGTCNAARAAYGCNATHAARACNGGNMGNTAYAAY AGYACNAARAARACNATGGAYATHYTNGARGTNAARAARYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARGARMGNATHGARTCNGGNYTN GARGARCCNACNACNAARGARGGNMGNAARAARAARAARCARAARGGNAARCCNCARACN ATGTCNYTNGARCARTTYAAYCARYTNCCNAARGARAARCAYGTNTCNGGNTCNGAYGAY GAYTCNGGNGARACNAAYGGNGAYGCNYTNCCNCCNCARACNCARACNMGNGTNCCNCCN ACNCARCAYGAYCCNAARTTYTTYAAYGAYGTNGTNGAYGAYGCNCAYCAYATHGTNAAR CAYGARAARATGCARGARGARTAYMGNAARCAYTAYGCNTCNGAYAAYGTNGTNGTNGCN AARYTNMGNAAYGAYYTNGARYTNAARGARAARGAYYTNTCNTCNYTNAARGARCARGTN GARACNATGGARGGNGARYTNAARCARGTNAARAARMGNAAYAARCARYTNTGYTTYATH YTNGGNCARGGNGARATGAARGARAARTCNCARGTNYTNYTNCARGTNGARGARYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ---GAYGARGARGCNGARACNGAYTCNAAYGTNCARAAYCAYAARYTNGTNTGYGCNATH GCNTCNAARCCNCAYGTNCCNGARAARTGYCAYAAYTTYYTNTCNTCNYTNGAYAGYACN TTYTTYTGGTGYAAYTTYTGYTCNTAYACNACNCCNCAYAARTCNYTNYTNAARTAYTGY CCNTAYGARTCNTTYTGYMGNTCNGAYATHGTNMGNCAYATGGCNAARATGCAYAGYGGN TTYGAYGARACNTCNYTNGGNTTYAGYTAYTGYACNTTYYTNTTYGAYTTYYTNMGNGTN ACNTCNMGNTCNGAYGAYAAYGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNGAYAGYTAYATGTAYCARACNGTNGGNCAYCAYGCNATHGAY YTNTAYTCNGARGCNATGGARATHCCNYTNTAYGCNMGNATHATHAARGGNACNAGYATH TGYATHGGNMGNGAYTAYGTNCCNCARGCNGGNGAYGARGTNGARGAYYTNTAYGARYTN YTNTCNGARGTNAARMGNGARAARAAYGTNGAYGCNGTNTCNGTNGGNGCNATHYTNTCN GAYTAYCARMGNGTNMGNGTNGARAAYGTNTGYCARMGNYTNCARYTNAARGTNYTNTCN TTYYTNTGGMGNMGNGARCARGARCARYTNYTNMGNGARATHATHGCNTGYGGNGTNAAR GCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------MGNTTY GGNGAYMGNGTNGCNGGNGAYATHTAYGAYYTNTCNYTNGARATGGARGCNYTNCCNCCN MGNYTNGARCARATHGAYGCNTGGGGNCARMGNGTNGAYAAYYTNGTNACNTGYTCNGCN TGGCARAARATGAARGARATHGCNTCNCARGARGGNATGATHGCNTCNGGNTAYGARMGN YTNTTYGGNGARTGGAGYMGNYTNTAYCARTTYTCNAARTTYTTYYTNTAYGARCCNTCN GCNGGNYTNTAYGGNTGYCCNYTNGCNATGTCNAAYGGNGCNGCNAARYTNYTNGARATG AGYGAYGARGAYMGNGARATHGAYATHGARAGYGAYGCNGAYGAYGARGARGGNTCNGCN TCNTTYAAYCCN---GAYGAYAARMGNGCNCAYCAYAAYGCNYTNGARMGNAARMGNMGN GAYCAYATHAARGAYAGYTTYCAYAGYYTNMGNGAYTGYGTNCCNCARGAYGAYCARAAR ------ACNAAYTCNTCNAGYAARACNTCNMGNGCNCARATHYTNMGNCARGCNTCNGAR TAYATHGTNMGNATGMGNGAYAARACNACNCARAAYGAYAARCAYATHCARATHYTNAAR CAYCARAAYGARGARYTNCARGCNCAR--------------------------------- ------------------------------------------------ATHAAYGCNYTN CARAARTCNCARGCNGGNGGNAARGCNATHGTNTCNTCNGGNTTYYTNGAYGGNCARCAY GAYGAYGAYTAYGAYAGYTTYGGNGARGARCCNGTNGTNGCNTCNCCNAGYAARMGNAAR ACNGTNAARACNAGYTCNAGY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GGNGGNTTYGTNTCNCARACNMGN YTNCARCARGAYGARCAR---GARTTYGARYTNATHYTNTTYAARCCNAARGCNYTNATG AAYATHAAYGGNTCNAGYGTNTCNAARACNGCNTGYTCNTTYAGYYTNAAYCCNAGYCAY ATHTAYYTNATHCAYGAYGARYTNGARMGNGTNGTNGGNAARTAYAAYATHAARGARGGN GGNAGYTCNGGNGGNCAYAAYGGNGTNCARTCNTGYATGGAYTGYYTNAARTCN------ ---------------AARGAY---------------------------------ATGCCN MGNYTNMGNATHGGNATHGGNMGNCCNCARACNAARGCNGARGTNGTNTCNTAYGTNYTN TCNAAYTTYCCNGARAARGAYCAYGARGCNATHAAYGARGCNATGAAYAAYGGNYTNAAR YTNYTNCARGARCAYATHTGGAARMGNGTNCCNCCNAAYAARCARYTNMGNATGCARAAR MGNATGGCNAAYTCNAARCCNMGNTCNCCNAGYGTNACNMGNTCNGCNGAYYTNGGNAAR GARTCNACNGCNACNCCNACNTCNCCNCCNAAYGCNCCNMGNGARCARCCNGTNGTNGAR ATGAARGCNGCNYTNAARGAYAARGAYYTNAARGAYGTNYTNGGNGARCCNGCNCCNTGY AGYAARGCNGCNGARGTN---------------------------------AGYAAYATG AAYGARTTYGTNCARACNGAYATGAARAARGGNGTNGCNATGTCNGCNCCNGARGCNCCN GCNGARTTYTCNYTNAARTAYAARGCNGGNGTNGCNCCNGCNMGNCCNYTNAARAARGTN TCNGARTAYCARAARCARTTYCARTGGAARAARGGNATGAARGCNTCNCCNYTNYTNGCN GCNCARGAYATHGTNTAYAARAGYAAYGCNAARYTNGGNCCNTAYAARTCNGAYGCNATH YTNMGNAARTCNGARTAYTCNMGNCARTTYAARGCNTGGAARCCN------TTYGCNGCN GAYGTNAAYTTYAAYGTN---------------------GTNAAYAAYAAYTAYGARATG AARAARMGNAGYAARAGYGCNGGNGCNGTNTCNCAYAARTCNAAYGARAARGCNGARGAR GARACNGARGTNGARAARAGYGCNGCNGAYYTNAARGARAARYTNGCNAARACNCAYGGN AARATHMGNMGNYTNGGNTCNGARTAYMGNGCNAAYTTYAARGCNCCNGARMGNTAYAGY TAYAGYYTNGGNGCNTGGAARGGNGCNGAYCCNCCNCARYTNATGCCNCARACNAARAGY GCNGAYGTNCCNGGNGARAAR---------------ACNAARGCNCCNGCNGTNCCNTCN GCNTCNAAYTGGTTYGTNGARGTNYTNGARYTNMGNMGNMGNGCNMGNGARTAYMGNAAR MGNTCNCARGGNACNCAYTTYTCNMGNGARCAYYTNGTNCARYTNATGGCNAARCARAAY GCNTGYTGGGAYGCNACNTCNGARGARTCNGCNACNGTNAAYGCNYTNAAYYTNGARACN TCN------------------------------YTNGCNYTNAGYAARCCN--------- ---------------CAYYTNGGNYTNCARCARGARGAYGARACNTGYTCNGAYGTNTCN GARGCNGAR---------------------AARGTNYTNCCNACNAARCCNAAYMGNCAR CARCARCARYTNAARAGYAARAARGCNGCNTAYYTNGARGARCARAARCARAARGTNGCN GARCARCARAARAARATHGAYGAYGCNTTYGARCCNGARGARAARGARGTNTCNAAYGAR GARGAR---------------------CARGGNMGNYTNACNACNCCN---GARYTNCAR GAYGAYGTNAGYGTNAARMGNCAYCAYYTNGAYYTNACNACNCCNGCNGTNGGNGGNGCN YTNYTNACNTGYCCNCCNACNAAYGGNAAYAARYTNATHATHACNTCNMGNTCNGGNGAR AGYTAYGTNACNGTNTCNGAYGTNGCNCCNGTNAARTCNACNAARACNTCNGCNGCNATG GARCARYTNYTNGCNATGCCNATHYTNGGNCARCCNTCNGGNGAYACNCAYGCNYTNMGN GAYGARGAYTCNGCNYTNGAYMGNCCNYTNAARGCNMGNTAYATHATHACNCCNYTNCCN TCNAGYMGNGAYGARGAYAARGARAAYAARAAYAAYGGNGARCAYAARAGYAARAGYCAR CARCARGGNAAYYTNTCNACNATHAARGARGGNGTNGGNMGNACNTAY---GARAARTAY ACNCCNGTNACNYTNGAYGAYATHMGNAARAGYGGNTGYGGNAARAARGAYGAYGAYGTN ATGTCNGTNTCNATGATGTCNGTNGCNTCNAGYAGYTCNYTNGCNTCNGARGTNYTNGAR MGNGCNMGNMGNMGNCARAARGARTTYTGGGGNAARAARGAY------------------ ------------------GARMGNATHYTNATHAAYAAYCCNTCNGCNAAYGTNGTNTCN GCNGGNATGYTNCARGGNTAYAGYYTNGGNTTYGAYATGCCNGARGGNAGYGAYGAYGAY TAYAAYGGNGCNGCNGCNAAYATHAAYTCNGAYGARAARAGYTTYGTNMGNGGNATHGTN TGGGAYATHGGNGTNGAYCAYYTNGARTGYYTNGAYMGNCARGARACNGGNTAYAAYGCN ATHCAYGTNGAYGTNAARYTNGAYGAYGGNCARACNGTNAAYTGYMGNACNTAYCARATG ------GCNAGYYTNTCNGGNMGNAAYYTNCCNAAYCCNTAYTAYAARAARGTNYTNATH GARGGNGCNMGNCARAAYGGNYTNCCNGARGAYTAYATHAAYTTYATHAGYAGYTTYCAR GAYACNGGNAGYCARGARCCNCCNCCNGGNTAYAARMGNGTNYTNGARGTNAARAARGGN AAYAARCARTGGYTNCAYCCNGCNGAYGCNYTNYTNAARGGNCAYATHYTNTAYACNGTN AARTTYYTNGGNGARTGYAGYGTNGARGARCCNAARGGNACNGAYGTNGTNAARAGYGCN ATHACNAARATGAARTTYAAYAARCAYATHAARMGNGCNGARGGNCARAARYTNCCNAAR GTNGARYTNGTNATHTCNGCNGARGCNGTNAARGTNYTNGAYCCNAARACNMGNATGGTN YTNCAYCARTAYCCNYTNCAYMGNATHTCNTAYTGYGCNGAYGAYAARTCNGAYAARMGN ATGTTYACNTTYATHGGNAARGAYGCNAAYAGYAAYGAYCAYTAYTGYTAYGTNTTYGAY AGYGARAARTGYGCNGARGARATHATHYTNACNATHGGNCARGCNTTYGAYYTNGCNTAY AARMGNTTYYTNGARACNTCNCARCARGARACNGAYATHAARAARCARTAYCARGTNYTN CARAARMGNGTNCARTCNYTNCARCARGARAAYGARGCNYTNMGNAARMGNGTNTCNGAR YTNGARAARYTNAARGAYMGNTCNGAYATHGCNGAYTAYATGAARAGYAAYCARATHTTY GARATHACNTCNGTNAAYGTNAAYACNCARGARAGYTCNACNGAYGAYGAYATHGAYAGY CCNTCNTCNGCNGARTCNCARATHTAYAGYACNGTNGTNGGNMGNMGNYTNGARAAYYTN ATGYTNAAYGARGAYGCNTCNAGY------------ACNCCNTCNTCNCARACNAAYGGN ACNCAYCAYAAYCCNTTYTCNACNCCNTCNCCNGGNGCNCCNCCNATGYTNAGYCCNCCN CCNGTNAAYACNMGNACNYTNMGNGCNGGNACNAAYCCNAAYACNCCNACNTCNAGYTCN AAYTTYTTYCCNAGYCCN------------------------------GCNCCNGCNCCN GGNCARATHGAYCCNTTYGGNATGGARGCNTTYAAYCCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AGYGGNCCNTCNCCNCAR AARAAYAARAARMGNTGYTTYACNTGYAGYTGYAARYTNGARYTNGCNCARMGNACNATH GGNAARTGYMGNTGYGAYMGNATHTTYTGYGCNGTNCAYMGNYTNCCNGARYTNCAYAAY TGYGAYTTYAAYCAYAARGARGAYGGNMGNMGNGARGCNMGNGARAARATGGTNAARCCN ACNMGNCAYATGGGNACNTCNTTYMGNMGNGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GAYCARAARAARAARGARGTNGAYGAYGTNAARCAYAARYTNGARAAYCARACNACNACN GARGGNGAYGCN---GARAAYGARAARAAYTCNGGNGAYGGNTCNACNTCNMGNAAYGGN CARGCNCCNCARACNCCNACNGCNGARGGNGARAAYATHTAYCARGTNCCNCCNAAYAAY GCNCCNGTNAAYGGNAARCARGCNGARCARGTNGCNAAYYTNYTNGAYYTNGARGAYCAR GCNGAYCAYATHYTNAARGGNATHGARCARATHAARAAYYTNGARTTYGAYTCNTCNGAR GTNATGTCNACNACNGCNYTNATHYTNGARAAYMGNCCNGTNAAYYTNCCNTCNAARAAY CCNGARGARGARGARAARCAYMGNMGNGARTAYACNGARATGGTNGARGCNGCNAARMGN AARGARCARAARGAYYTNAARYTNAARAARAARYTNCARGTNCARMGNAARYTNGARGAY CARYTNATGTCNGCNGCNCARATHTGGAAYAAYGAYATHYTNCCNTGYTGGGAYTCNATG AARCARTCNAARAARGCNMGNGAYATGTGGTGGCAYGGNYTNCCNCCNTGYATHMGNGGN ------------AARATGTCNGGNATHACNTGYYTNACNTGYAAYGTNGCNTTYGGNGAY GTNGARATGGGNMGNATHCAYTAYAARACNGAYTGGCAYMGNTAYAAYYTNAARMGNAAR GTNGCNAAYYTNACNCCNGTNACNYTNGARCARTTYCARGARMGNCARAARYTNCARGAR CARYTNATGACN---ACNGCNGARGARCCNACNGARACNYTNTTYTGYAARCCNTGYAAY AARTCNTTYGGNTCNTCNAAYTCNTAYGAYAAYCAYATGCARTCNAARAARCAYAARGAY ATGGTNGCN------TAYAGYAAYAARAARTCNAARGGNAAR---------AARAARCAR AGYAAYAARTCNGCNGGNACNGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ACNTCNTCNTCNTCNYTNGARATHATHAARCCNACNGARTCNGTNGARACNCARAARGTN CARTCNCAYCAYAAYCARGCNATHYTNYTNACNTGYYTNTTYATGGARGGNATHGGNAAR TTYGCNATGGTNYTNMGNGARGAYTTYATGGTNCAYYTNATHCARACNYTNTAYCCNYTN GTNGARAAYYTNGGNAAYCAYAAYATHTAYATHAGYTGYACNGCNTAYGCNACNYTNACN CARATHTGYYTNGCNTGYGGNTAYMGNTCNATHGAYCAYYTNATHCARGCNAAYGCNGAY TAYYTNGTNAAYAGYGTNTCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TTYCARTTYACNGGNGAYGAYTAYGGNCCNGTNGAYTTYCCNAGYACN YTNCCNAGYGAYYTNCARGCNGGNATGGCNTTYGCNGGNGGNGGNCCNGTNTTYCCNCAR AAYCARMGNGGNAGYGCNTAYGGNATG---CCNTTYCAYATGAAYTAYTCNCARCARGCN TCNATGCCNTCNATGTCNAGYYTNCCNACNAGYTCNTTYMGNAGYMGNTTYGCNGAYTTY CCNCCNGAYCARAGYCCNCAYYTNCCNATGCCNATHCCNTCNTCNACNGCNGGNATGATG GCNGAYMGNYTNCCNAGYTTYAGYACNATHGTNTCNAGYAGYACNAGYAGYGAYYTNGCN AARAGYAGYCARGCNYTNTAYTCNAGYATHGGNACNTCNYTNTCNGGNCARCARCAYGCN TTYCARCCNTCNGGNAGYMGNTCNGTNCARCCNCAYTTYGAYAGYTCNATHCARGAYCAR GTNTCNTCNAARAGYTAYAAYAARACNTCNCCNYTNGGNTCNACNTCNCCNGGNATGAAY ACNTAYAGYAGYAAYATHCCNCAYTCNTCNATHATHCARGGNTCNTCNCAYAAYGGNGGN AAYCAYYTNTCNTCNCAYTCNCCNMGNTCNTAYAARGTNGARGAYGCNTCNCARCARCCN TAYYTNGGNTCNATGCAYYTNGAYMGNCAYACNGCNTTYTCNCAYGGNTCNYTNCCNGGN TCNCARAGYCARGARTCNATGTCNYTNCCNAARTTYAARTAYAARTAYYTNTCNCARTCN CAYCARGCNCAYCAYCAYCARTCNGGNCCNTTYAARTTYTAYATHYTNGGNAARACNGAR MGNCARACNGTNTTYAAYMGNGGNACNCARACNAARGARGARTCNATGTCNCCNAGYTTY ATGGAYTCNGCNGGNAARGCNACNATGACNACNTGYGTNGCNAAYAARGCNACNATHGTN ACNGTNGGNATHGTNAGYMGNCCNGCNAAYYTNGGNGGNCCNYTNTCNAARTCNACNGAY AGYACNGGNATHATGGCNACNGGNAAYGGNYTNCAYGAYCARMGNTAYGGNCARAGYAGY GAYAAYTAYGARCARGTNATGGARGARMGNAARGCNAARGCNMGNGAYYTNGARCARGAR MGNATGGARGTNAGYGTNMGNATHGAYGAYACNCARTAYGTNCARGTNGGNAAYGTNAAR MGNTGGCARTGYAAYGARTGYGAYAARTCNTAYACNACNAARCAYAAYYTNGTNATGCAY GTNYTNGAYCAYAGYGGNATHAARCCNCAYYTNTGYYTNAARTGYGGNAARTAYTTYAAR CARYTNAGYCAYYTNAAYACN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNCARGARCAYAARGGNATGATHGCNGTNCARGGNAGYYTNTCNGTNYTNYTNGAY TCNYTNATHTGYGCNTGYGGNCCNYTNYTNTGYYTNACNCARCARGTNCCNGGNATGGAY GGNTGYGCNCCNTCNGTNCAYTCNCARACNYTNGAYAGYGTNGCNTAYGTNATGCCNGGN YTN--------------------------------------------------------- ------------------------------------------------------------ ---ATHGCNTCNATHCAYMGNMGNTGYGTNGGNGCNACNCCNYTNATGGCNGARCAYMGN TTYYTNGARAARGTNAARTGGYTNGARATGTAYGGNGTNGAYYTNCAYCCNGTNCARGGN GARAGYAAYATGGARTAYTTYYTNGGNYTNACNCCNACNGGNATHGTNGTNTAYAARCAY AARACNAARGTNGCNAGYTAYTTYTGGCCNMGNGTNACNAARGCNGAYTAYAARTCNAAR AAYTTY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYAARATG---AGYGTNCAYCCNACNCARGCNCCNCCNCCNTAYACN CCNAAYGAYCCNGCNTAYCCNCCNCCNGGNCCNGCNGGNTAYTAYGGNCCNCCNCARCCN ------------GGNTAYGGNGGNTAYGGN---ACNGCNCARTCNTAYCCNTAYCCNCCN CCNCARGGNTAYCCNCCNCCNCCNCCNCARGGNCARCARCCNTAYCCNCCN--------- ------------------------GCNCCNCCNCARGGNCAYCARCCNTAYCCNCARCAR CARTAYCAYCCNGGNCCNTAYCARCARCARCCN---CARCARGTNGTNTAYATHGARGAR AAYMGNCAYGAYMGNGAYAARGAYAAYGAYGCNGARACNTGYTGYATHATHGCNYTNTGY GCNGCNYTNGTNTGYTGYTGYYTNATGGAYATGGCNGARAGYAAYATHCCNAARCARGAY TTYGCNCCNCCNTGGYTNAARTTYCCNAAYACNGAYACNACNAARTCNCCNAAYCARAAR CCNAAYCAYCARGGNGAYMGNAAYMGNCARMGNMGNGARGAYCCNTAYTCNGCNMGNACN GAYTAYAGYMGNYTNCAYMGNCARAGYTCNTTYGAYTTYCAYGARGGNAARMGNTTYCCN CARGGNCAYGGNAARTAYMGNCAYCAYTCNGTNGAYGAYGAYTAYTAYGGNTAYCCNTAY GGNTAYGGNTAYTAYCCNTCNAAYTAYAAYTTYGARAARTTYGAYATGCARTAYAGYTCN CARCCNTCNYTNGCNMGNGCNGGNAAYMGNGAYGGNAARTAYCARCCNGCNMGNTTYTCN CARGGNTCN--------------------------------------------------- ---CARMGNMGNGGNCAYTAY---GAYAARGARCAYTCNAARGAYAGYMGNGAY---GAR GCNAARGCNMGNGAYMGNAAYGGNGAYYTNGAYMGNCCNTAYAGYGAYGAYTTYCCNTCN YTNAAYGGNTCNGGNGARAGYCAYGTNGARTCNAARCCNAARCCNGGNTCNGGNGTNTGG GARAAYCCNCCNAAR---TCN---AGYMGNAAYGARGAYTCNCCNGAYCCNTCNAARGGN TCNTCNCCNGGNATHTAYAARGCNYTNGTNCCNAGYAARGGNGGNCARGCNAARAARCCN GCNTGGGAYGGNATGMGNATGAAYGGNAAYGTNMGNGAYTCNTCNCCNYTNAGYCCNTCN AAYAARCCNAAYCAYAARGARGGNACNMGNCARAGYCCNACNCCNGAYYTNGCNATHGTN ACNCARCCNAARAARYTNGGNGAYAARAARAGYGARTTYYTNMGNGCNYTNMGNAAYGAR TCNACNGTNMGNAGYGGNGAYCARCAYCARTCNATGGAYCAR---------------AAR CARGARTCNAARGARGGNTCNGAYAGYCCNATGAGYGARGARGCNGGNTCN---GGNTAY ATGAAYGGNGAYGGNATGACNGAYTCNAAYGARAAY---ATGYTNAAYGGNAARYTNYTN TAYAAYGGNGTNGCNAARGAYAGYTAYGTNAAYGGNGARGGNGGNGARACNYTNATHGAR GARGTNGAYCAYATHAGYYTNTCNGGNGARGARGARGARAARMGNYTNYTNYTNTCNATG GGNTGGGTNGARGARGAYAAYACNGARTAYGTNATHACNGAYGAYGARATHMGNGARTTY CARAAYYTNGTNCARAAYCAYAGYCARAARCAR---AAYGGNYTNAARACNCCNYTNMGN AAYGCNYTNAAYMGNAARTTYGTN------AGYAAYGGNATGYTNAAYGGNACNCCNTCN GARGARGAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYGGNMGNTAYCCNMGNGARTAYAAYCCNAARGTNCAYGGN CCNTAYATGCCNGGNMGNTTYTAYGGNAARCCNGAYACNCCNATHGGNCARGTNAARYTN GGNGARYTNGGNACNTGGTTYGGNMGNMGNAAYAARAGYGTNGARGGNYTNTGGGGNGTN GTNCAYMGNGGNTAYTGGMGNTGGGCNTCNAARAAYYTNCAYGTNMGNAGYTCNGGNTTY GTNCCNTTYGGNCARGCNGCNATGACNYTNAGYATHATHTAYTTYGCNYTNYTNTAYAAR GARMGNAGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNMGNYTNGCNAAYATG AAYTGGCARACNTCNCARAARCARGCNAARCAYCAYGCNACNGARATHGGNMGNTAYGAR GAYACNYTNGCNCARYTNCARACNGAYTCNGARAARYTNCARGARCARTAYMGNAARACN TGYTCNGAYYTNATGGARGCNGAYAGYAARATHCAYGARYTNAARGTNCARGTNACNACN GTNCARGGNAAYCAYAARGARGCNATGGARCARYTNACNGAYAARGCNMGNCARYTNGCN ATGATHAARACNGAYGCNGCNAARYTNTCNCARCARAAYTCNTCNATGMGNGARGARATH ATGATHTAYGAYGARMGNATGMGNAARYTNCARTCNGARYTNMGNAARTCNCARGARYTN AAYAARGCNACNGARGARGARYTNCARCAYTTYGARGARMGNTAYACNAGYYTNCARGTN GAYYTNGTNTCNAGYCARGARAARCARAARCAYGCNYTNCARGARYTNTCNTCNAARGAR GARGARYTNGTNGTNATGAARGTNGARYTNAGYACNYTNCARGARMGNCAYAARAAYTCN TCNGAYGAYTCNAAYAARYTNCAYAAYGARYTNGAYYTNATGAARCARAAYTAYMGNAGY GCNAAYGARGARATHGGNAGYYTNMGNGTNGCNYTNGARGARTCNMGNGCNAAYGGNGAY MGNYTNCAYMGNGARAGYGARYTNGTNGTNCAYAAYGTNAAYACNTGGGTNCARGARCAR AARATGGCNAAYGARAARYTNGGNAAYAARATHMGNGARCARAGYAARGCNATHATGTGY YTNACNTCNGARAARGARGCNYTNYTNGAYCARGTNCARAARATGCAYAARAAYTAYAAY MGNACNAARGCNGAYYTNGAYGARAARAGYATHGARGGNGARAARYTNMGNGCNYTNCAR TCNCAYACNGCNCAYCARCARATHGTNYTNAAYCARYTNAARAGYMGNYTNCARGARCAY GARGTNGARCARGAYCARGAYYTNAARACNAARGTNGCNACNATHGARGAYYTNCAYYTN MGNYTNAARTCNAAYATHGAYAGYATHCAYCARYTNAAYCARCARYTNAGYACNYTNCAR AARGAYAAYATHMGNYTNMGNAGYGARYTNGAYMGNGARATHGCNACNMGNCARGCNYTN GARATGCARATGCARAGYAARGAYCARYTNGTNGARAGYYTNMGNACNCARYTNGAYTCN AAYTCNTAYAARMGNYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AGYCARYTNTAYAGYAARGARAAYGAYCAYGGN GARYTNATHGTNMGNAARMGNTCNMGNGGNCARMGNGAYMGNYTNMGNCARATGMGNYTN GGNGGNMGNMGNTTYACNGTNCARGGNYTNGAR---------AAYTAY------CARCCN GGNYTNTAYGAYGAYAGYCARTCNGAYMGNAGYGAYTCNTCNAARACNGARGTNCCNGAR GAYYTNYTNTCNGTNTTYAARAAYATGACNAARGARGARYTNYTNMGNGTNGTNATHAAR ACNAARGCNCARATGATHMGNAARGAYCARTAYATHAARGAYYTNGARAAYTAYATHGAY GAYYTNYTNGTNMGNGTNATGGARACNACNCCNMGNYTNYTNAAYMGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MGNACNCARTCNCAR CCNGCNACNMGNAARCCNAARAGYGAYMGNMGNAAYMGNAGYGARAAYGGNAARTGYTCN GTNTGYCCNTAYCCNCARGCNCAYGCNTCNACNAGYAAYAARAARACNGARAARMGNCCN TCNAARCCNAARMGNAARGGNYTNAARGGNYTNGGN---AGYAARAARAAYAARGARMGN AGYGAYTCNAARGARGAYAARYTNTGGTAYTCNGAYAAYGAYGCNCARAAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGCNTCNACNTCNCARAARCCNAARAARGGNATHYTNAARCAYTCNGGNAGYATHGAY CARAGYAARAARGARATHGARTGGGAYGARATGAAYATHYTNGCNACNTAYCAYCCNGCN GAYAARGAYTAYGGNTTYATGAARGTNGAYGARCCNCCNACNCCNTAYAAYMGN---TCN ATHGAYGGNGARGAYGGNGAYGARGCNGARGTNGAYMGNAARGGNAGYATHGAYGARGTN AARGAYYTNGAYCCNGCNCARYTNGCNTCNMGNYTNGARCARAARGGNGARAGYAGYMGN CARMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYATGMGNCAYATHCAYGCNGARATHGGNGAY AAYYTNGCNCARMGNMGNMGNMGNATGGGNACNTTYMGNAAYAAYACNGGNCCNCCNCCN GARMGNMGNAGYACNATHAGYAGY---ATGACNCCNAGYAGYTAYCARGTNACNMGNATG MGNAAYYTNTCNGGNGGNAGYAGYGGNAGYACNGCNAGYGGNAGYAGYAGYGGNAGYTCN GTNCAYYTNGAYAAYCARTAYTCN------GAYAAYCAYATGTCNTTYYTNGARATH--- ---TCNCCNTTYGCNAAYTCNACNACNGTNCARMGN---------------------GGN GARTCNCAYMGNAARYTNGAYMGNAGYYTNAGYGAYAGYGARAGYGAYMGNYTNGGNAAY ACNTCNTCNTCNTCNCAYMGNTCNATHAAYTCNAGYMGNTAYAARACNGARYTNTGYMGN CARTTYGARGARAGYGGNTCNTGYAARTAYGGNGAYAARTGYCARTTYGCNCAYGGNATG CAYGARYTNMGNAAYYTNGCNMGNCAYCCNAARTAYAARACNGARMGNTGYMGNACNTTY CAYACNATHGGNTTYTGYCCNTAYGGNCCNMGNTGYCAYTTYATHCAYGARGAYGAY--- AARGTNGAYTCN---CCNGCNAARYTNCCNTCN--------------------------- ---AGYACNTCNAGYGGNAGYAGYAGYCCNTCNYTNAGYCCNACNAAYAGYGARAAY--- GTNGGNACNTTYTCNTAYTCN---GARACNAGYCCNMGNYTNACNACNGTNAAYGTNGAY AAYMGNCARATHAAYGCNYTNACNGTNAAYATHAAYAAYTAYAGYAAYAAY--------- ------------TGGGAR---CAR---CARTTYCARTCNYTNAGYYTNAAYGGNAAYACN GGNAGYGARAAYCAYAGYAAY------ATGTCNAAYACNCARAGYTCNAGYTAYYTNAAY AARAAR------ACNAARGARTTYGAYATHTTYAGYTTYGTNTCNGTNTTYGAYTCNMGN GARGCNGGNYTNGAYAAYGAYCCNAAR------CCNTCNTCNYTNAAYTCNTAYAAYGTN CARTCNAARYTNGAYAAYTCNCCN---TCNTTYTCNGAYTCNTCNYTNYTNTGGCARAAY TCNTTYGCNGAYYTNAGYCARAGYATHMGNGCNGTNGAYTCNTTYAAYCAYTCNCCNACN GGNTCNACNGGNTCN------------------------GAYAGYAGYGGNAGYGAYTGY TGYAGYAGYACNGARAGYYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------AARAAYMGNTCNTGGACNGTNTAYGGNGARCARYTNGCNACNAARTGY AARGARGAYCCNMGNGARTTYTAYAAYAGYGTNAARMGNATGMGNGARGARCCNTTYAAY CCNACNGARATHGTNAAYGAYGARAAYGGNAAYCCNATHTTYAGYAARCCNGARATHAAR AARMGNTGGAARMGNTAYTTYCARGARYTNYTNAAYCCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNMGNMGNATHGGNAARTCNTCNGTNACNTCNGAR MGNTTYGARAARAGYYTNATHAARTTYTGYCAYATHTTYTCNGAYTTYGAYGCNTGGGAR YTNGARAGYTAYGGNTAYAARCAYGCNAARATHACNACNAARYTNMGNATHYTNAARAAY YTNYTNGARTTYCARTTYGAYTAYAAYGTNAARTTYAARGARAARGTNAAYGARMGNAGY GCNGARGAYACNMGNTTYYTNCCNATHGGNMGNGAYAARGARGGNCARGCNTAYTGGTAY TTYGARGAYAARGAYCAYAAYYTNATGATHTAYAARGARGARCARGAYGAYGARGAYGCN GAYACNTGGCARYTNGTNTGYMGNGAYMGNAARGARYTNGCNGTNYTNGTNAAYGCNYTN CARTCNACNATHACNYTNAARGARGAYGAYAARAGYACNGARTCNAGYAGYAARGARGGN AGYCCNGAYAARGAR------TTYCAYGTNGTNCCNCCNCCNCCNCCNYTNGCNGARGAY ATHTTYGCNGGNMGNMGNGAYGTNMGNGAYCCNAARTCNGTNYTNGARAARCARATHACN AGYTCNAARGGNACNGTNMGNGGNTTYAARAAYMGNGTNAARGCNGGNATHGCNACNTTY TGGGCNCARCCNGARGAYCARMGNAAYTAYMGNCARYTNGARCARGGNAARATHGTNATH TAYGCNTCNTCNATGAAYGTNGTNMGNGCNACNAGYGARMGNTGYAARGTNGTNMGNGCN YTNYTNCARAAYCAYATGGTNMGNTAYGARGARMGNGAYYTNTAYATGAGYMGNGARATH CARCARGARYTNTAYCAYMGNYTNCARCARGARGGNGTNATHGAYAGYACNYTNCCNCAY GTNTTYGCNGAYGGNATHTGGATHGGNGGNGCNGCNGARYTNGARAARATGAAYGARGCN GGNCARYTNMGNAAYYTNYTNAAYAAYTAYCARAARATHAAYGTNMGNATHATGTGYGGN CARTGYGGNGGNTAYMGNTTYGTNCCNTGYGARATHTGYCAYGGNAGYAARMGNTCNYTN ATHMGNAAYCAYTTYACNGARGARTTYTGYGCNYTNMGNTGYATGCAYTGYAAYGARCAY GGNYTNMGNMGNTGYCARTTYTGYGARGAYCARCARGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CCNMGNATHTCNTCNTCNGAYTTYGARTTYGCNYTNCAYGCNGTNAGYCCNTCNYTNAAR AARGGNAGYGAYTGYGTNGTNGARYTNAARCCNGTNTCNTGGGAYTCNATHGGNGGNYTN GGNGAYGTNAARGCNGARYTNAARCARGCNATHGARTGGCCNYTNAARTAYCCNCARGTN YTNCARMGNATGGAYYTNYTNCARACNAARGGNATHYTNYTNTAYGGNCCNCCNGGNTGY TGYAARACNACNYTNGTNAARGCNTTYGCNACNTCNTGYCAYGTNAAYTTYYTNTGYYTN AAYGGNGCNCARGCNTTYTCNGCNTAYGTNGGNGARTCNGARAARATHGTNTCNGARGCN TTYMGNACNGCNMGNGCNYTNGCNCCNTCNATHYTNTTYATHGAYGARATHGARTCNYTN GTNGGNAARMGNACNTCNGAYAARAGYCAYTCNMGNGTNCARGARMGNATHYTNGCNACN ATGYTNAAYGARATGGAYGGNGTNGGNAGYMGNYTNGAYAAYAARATGGAYGCNACNGAR TCNTCNGTNGAYAGYTGYGAYACNTCNCARMGNGTNYTNCCNTCNGGNGAYCARGGNACN GARACNAAYMGNGTNGAYGTNCARACNACNACNAAY------GGNTCNTCNCAYGAYCCN AAR---------GTNATHGTNGTNGGNGCNACNAAYMGNAARGAYATGYTNGAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARGARGTN AGYAARYTNCARTTYGARYTNGARTGGMGNGARTCNTCNTTYATGGAYAGYCARCARACN TGGGCNGARMGNTTYGAYMGNGTNTGYCARGARAAYGCNYTNYTNATGTCNAARYTNGAR GGNMGNTCNGARGARYTNMGNMGNATGACNGCNCAYAARTCNGCNATHTCNMGNGARMGN GAYGARYTNYTNGCNYTNYTNGAYGTNACNGARMGNYTNAARTAYGARCARGGNAARAGY ATGATHGCNGARGARGARTAYGGNACNTTYTCNTCNTCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGTCNGCNTTYACNMGNYTNMGNGTNACNGTNGAYMGNYTNTTY GTNAARCAYYTNTTYGCNACNAAYGTNYTNACNTGYGGNACNYTNYTNGGNATHGGNGAY TGYATHGTNCARCARATH------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNTCN ACNATHCAYATHGAYACNGAYYTNGARMGNGARCARAAYGARGAYACNGTNYTNGCNAGY CARYTNYTNGTNCARGGNYTNMGNYTNAAYGGNGAYACNACNAARGCNGCNGARGAYAAR GCNAAYTCNGARAARCARCARGTNATGGGNYTNATHGAYAARCARCARCARACNGARGAR AAYGARYTNACNTTYATGYTNGCNYTNGARCARAAYGARGARGCNGARAARYTNMGNAAR GARAAYGCNATHAARAARMGNATGGGNATHAARGARAAYCARCARYTNTAYATHGARGAY GTNATHAARGARMGNMGNGCNYTNGCNAAYGCNAGYGARACNCARGARGAYGAYCAYTCN GARATGYTNAAYATGYTNGCNTCNATGCAYATHAAYTTYATHTCNAARYTNAARAARAAY MGNAAYTTYTCNCCNGAYCARATHGAYGAYTAYATGTCNAARATHCARGTNGAYYTNAAR GAYGTNAARTCNACNATGGAYAARGARAARGAYYTNAARGARAARGARATGTTYAARACN YTNAGYCARTCNAARMGNAARYTNYTNGCNGARAARATHAAYGARCAYAARACNGARYTN AAYGARTAYATHAARMGNAAYAARGCNCARCARACNGAYGGNCCNGTNGAYCCNNNNTCN TAYATHGGNGGNYTNGTNGAYYTNAARTCNMGNCARMGNAARGARYTNAGYTCNYTNGAR AAYAARATHGAYCARGAYCAYGCNAARCARYTNGARGARATGMGNGAYCARYTNGCNATG AAYGCNAARAAYGARYTNGGNACNYTNGARMGNAGYYTNGTNGARAAYYTNAARCARGAY GGNATGMGNGAYGARGTNATHGARAARATGATHGARACNAAYAAYMGNAAYATGGCNGAR YTNYTNTCNAARCARCARATGAAYMGNMGNAAYCARGARGCNAARYTNAARGAYGARYTN GCNMGNMGNAARMGNGARTGGGARCARMGNAARACNCARGARMGNAARGARCARCARGCN YTNMGNGAYCAYGARGCNGARGTNGTNGAYAARYTNYTNAGYAGYCARGTNYTNATHTCN GAYGAYGARMGNGARAARATHYTNAARGARCAYGARAARCARATGGTNAARYTNGARAAY AGYYTNACNYTNAAYAARYTNMGNCARCARMGNATGYTNGARGARAARYTNGCNATHAAR MGNGCNMGNMGNATGGARGARYTNCARCARAARCARAARACNGARYTNGTNAARCARMGN MGNATGGCNGARAAYAAYGGNGARGARGAYGAYYTNGGNACNCARMGNCARGARYTNGAR ACNATGAARAARCAYGCNGARCARMGNATGGCNGTNYTNCARGGNGARMGNTTYAAYTTY GAYGARGARYTNGARCARATHMGNYTNGARATGACNAARGARMGNGCNYTNGTNYTNAAR GAYCAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ACNGTNGCNGARAARGGNATGACNATHTTYYTNGAYGTNTTYMGN MGNGCNGAYAARAAYGAYGAYGGNTTYATHTCNTGGGARGARTTYGTNTCNTAYTTYGCN GAYGGNGTNATGAGYAARGARGARYTNCARGARYTNTTYAAYCARATHGAYTCNCAYAAY ACNAAYAAYATHGAYACNGARGARYTNTGYACNTAYTTYACNCARCAYYTNGGNGARTTY AARGARATHTTYAGYATHYTNGARGAYYTNAAYMGNAARATGACNGARGTNYTNTAYAGY ACNTCNAARGTNTAYACNGARTCNAAYTTYACNGARAARTTYGTNAARMGNTTYYTNATG MGNGARATHYTNAAYCARATGTGYGCNYTNCARMGNCCNATGGARGCNGCNTCNGAYTCN YTNGAYATGCARGCNMGNGARGARMGNGGNGAYGTNMGNCCNGTNGARGTNGARGARGTN GTNAARAAR---CCNTTYACNAGYGGNATHGTNCCNGGNMGNATHGTNMGNMGNGCNAAR MGNCARGTNAGYGCNATGAGYACNGGNTCNAAYGARGTNACNGAYTGYCAYCCNGGNGGN ---YTNGCNATGACNAGYCARGTNGAYMGNYTNTCNGAYYTNATHAAYMGNYTNGARCAY AARATGAAYTTYGAYGGNTTYMGNGAYGARGARATHGTNTCNGGNAAYGAYGARATGYTN YTNYTNAAYYTNMGNGARTTYMGNGTNAARGCNGAYCARYTNGARGARTTYMGNGCNCAR YTNMGNGCNTAYGTNGAYGTNACNCARGGNTTYMGNGGNTGYYTNAAYYTNAGYGTNMGN GTNYTNAARGAYTCNAAYGCNTTYAAYGTNTAYGARGTNTGGTCNTCNCCNGAYACNTTY GARAAYAAYAAYGARGGNGARGCNAAYAARACNTTYGTNGARAARAGYTCNGGNYTNYTN GARAGYCCNGARTCNACNMGNACNATGAAYATHCCNGCNTCNTGGTGGMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARAARTTYGAR YTNGARATHCARAARGTNCAYGARTCNTAYGARGGNYTNCARAARTCNTCNCAYAARAGY AARGGNYTNTGGCARGCNATGAARATGMGNYTNGARGARMGNATHCAYYTNYTNGARTCN GARYTNGCN---AAYMGNGARGAYGGNGGNGCNTCNTCNTAYCCNTCNACNTCNACNACN AARGARYTNCARATHAARATHTCNGARAARGAYGARATGATHTCNMGNYTNYTNMGNCAR AAYCAYGARYTNGTNACNAGYAARGARAGYYTNGARGCNGAYAAYGTNCARGTNAGYGTN AGYYTNCARGARAARAARGCNCAYGTNGAYATHGTNGARMGNGCNYTNATGAAYACNCAR AGYAARGTNYTNGCNYTNGARGARGARTAYMGNAARAARCARGCNTAYGTNGAYAARGTN GARCARYTNCARACNGCNYTNGGNTCNYTNAARGCNGCNAGYAARCARGARAARAARGAR AARGARATGMGNATHMGNYTNCARAAYGARYTNGAYACNTAYGAYCARGARAARGGNGTN GTNAARGTNGARGGNAARGARGARGARAARAGYGTNGGNGTNYTNAARAARATGYTNGAY AARGAYGTNMGNYTNCARYTNGARTCNAGYATGGCNGARYTNGARCARAARTAYGCNAAR GARGCNACNYTNMGNCARYTNAAYATGGARGARATGTCNGARCCNCCNAARGARGTNMGN YTNGCNGCNYTNGARAARAGYTCNTCNGAYATGGARAARATGATHGAYGARGCNAARACN GARAARYTNAARCAYATGGARGARYTNCAYCARTCNCAYMGNAARGTNGCNGARYTNGAR GCNAARGTNAARCARYTNCARACNCARYTNGTNGARAARGARGCNATGGTNAARGTNTTY CARMGNTCNCCNYTNAGYYTNCCNMGNAGYTCNAGYYTNCAYGCNYTNTGYCAYTCNCCN YTNCAYTCNCCNMGNCCNTCNYTNATHGCNTCNCARACNACNGARTCNTCNAGYGGNYTN GGNCAY---------------------MGNGARTTYGCNACNGTNMGNCAYATGAARACN GGNAGYGCNAGYGCNGTNGARYTNGGNMGNAARATGTCNATGGARGARGAYYTNYTNATH AARGTNCARAAYYTNAAYGTNGARACNAARAGYGARTCNGAYGARGARGGNAARYTNTGG CAYGTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TGYTGYATGMGNGARATHCARMGNATHAARGAYACN GGNMGNGTNTCNATHAAYATHGGNGGNCCNCARGGNTCNYTNACNATHAGYGAYATHMGN YTNCCNYTNAARAARGAYTTYGTNACNAARATHGGNTCNACNCARGAYACNATGACNCAY TAYTTYATHYTNYTNGTNMGNAAYGGNTGYCAYATHATHTGYACNCARYTNYTNTCNACN CAYGAYCCNATGATGMGNGGNAGYYTNGAYTTYCCNAAYYTNATHAARATHAAYGGNATH ACNTCNGARTTYATHGTNACNATHGAYATHTAYAGYATGAAYATHAGYMGNGARGCNAAR AARGAYAARAARMGNAARACNCCNAARAARGGNAARAGY---GGNATGCCNATGGARAGY CCNGGNGGNTCNTAYTCNGTNMGNACNACNAGYTTYACNCAYGTNAGYTCNYTNCAYYTN AAYATGAARAGYYTNGAYAARACNTCNTTYCARYTNGARMGNYTNCCNTTYYTNTCNCCN YTNCAYGGNCARATHTAYATGMGNYTNAARTGYYTNATGGARAGYAAYGTNGARGARMGN GGNTTYYTNACNATGTTYGAYGAYGTNAAYGGNTTYGGNGCNTGGCAYMGNMGNTGGTGY GTNYTNTCNGGNAAYAARYTNTGYGTNTGGAARTAYCCNGAYGAYGARCAYMGNAARGAY CCNATGACNATGATHGAYYTNAARMGNTGYATHACNGARAARGTNTGYYTNGTNCCNMGN GAYATHTGYGCNMGNCCNAAYACNTTYGARATGACNACNGTNMGNCARCCNYTNAARGGN GARCAYGAYACNYTNGTNACNAARACNTAYAAYACNATGACNACNATHMGNCAYCARATG TCNGCNGAYACNAARGARGARMGNGTNATHTGGTGYAAYAARATHAAYCAYACNYTNGCN AAYYTNMGNTCNTGGCAYGCNGAYGCNYTNAARCCNATHAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------MGNTCNTCNGAYYTNACNTGYGCNGAYTTYATHTAYGCNTAYCCN ACNCARGCNYTNGTNGAYGCN---GGNATHAARAAYATHYTNYTNCCNGTNGCNTGGACN AAYGARATGGCNCARATGCARGTNYTNGCNTAYGTNCARGGNTTYAGYMGNGTNAAYAAY GTNACNGTNATHATGGCNAAY---CAYCAYATGAGYGGNGARTGYAGYGGNTCNGGNGTN TTYACN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AGYGAYTCNGGNAGYGAR GAYGTNAGYATGATHCAYGAR---TCNGGNCAYAARAGY---AAYGGNCARTAYGARGAY GAYATHTGYMGNGAYTAYATGMGNAGYGTNTGYACNMGNGGNAARMGNTGYMGNTAYMGN CAYCCNGTNATHGARGAYMGNCCNGARCCNCCNCCNMGNMGNGAYATHACNTTYTGYCAY GAYTAYCARAAYAAYGGNTGYTCNMGNCCNAGYTGYAARTTYYTNCAYTGYTCNMGNGAY GARGARGARTAYTTYCAYMGNACNGGNYTNYTNCCNCCNMGNYTNAAYCARCCNCARGCN ------TAYGCNAAYGTNATGAARGCNGARYTNCCNYTNTGYMGNGAYTTYYTNAAYGGN GAYTGYAARMGNGGNTCNAARTGYAARTTYAARCAYGTNAAYCCNGARMGNGAYMGNATH GARAGYMGNGAYCAYGAYMGNTCNTCNTAYGAYCAYCAYGAYMGNTCNTAYGAYCAYGGN CCNGARTCNAARMGNMGNMGN--------------------------------------- ------------------------------------------------------------ ------------------------TGGAAYMGNTAYMGNCCNYTNCCNCCNACNCCNTCN CCNACNCCNCCNCCNGCNAAYCARCCNGTNGGNYTNACNGAYCCNTAYAAYAGYYTNTCN MGNGARCARCARYTNTTYACNGARMGNATHACNTCNATGGGNTTYYTNMGNGCNCARGTN GCNMGNGCNGTNATGAARTTYGGNCARGAYGARAARGARGTNYTNGAYCAYYTNATHTCN GTNGAYAARYTNGTNGARAARAARTAYGCNCCNGTNCAYGCNGARGCNGCNYTNGARAAR TGYMGNAAYGAYGTNGAYAARGCNGARMGNTTYYTNAARATGCARTCNCARTTYGARGAR YTNGGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATHYTNACNTGYAGYCAYGTNGTNAARGAYTCNAAYYTNTAYCCNGTNACNATH MGNACNATHGARAGYTCNMGNAARYTNAARACNGCNGTNGTNTAYMGNCARAAYCCNYTN AARAGYCCNTAYGAYATHGCNGTNYTNGARTGYACNAAYGCNACNMGNCAYYTNCCNGAR AARTGGACNATHCARGCNGTNCARCCNTGYATHGGNGARGARGCNTTYGTNGTNGGNCAY GCNYTNTTYAGYCCNCAYYTNGCNYTNAAYCCNTCNGTNACNMGNGGNGTNATHTCNAAR GCNATHTCNAAYACNGAYMGNCCNATHYTNATHCARTCNACNTGYGCNGTNCAYCCNGGN GCNAGYGGNGGNCCNYTNYTNAAYGARGARGGNAAYYTNYTNGGNATHGTNGTNTGYAAY ACNAARGAYAGYAAYAAYCAYACNACNTTYCCNCAYYTNAGYATGTGYGTNCCNGCNGTN AGYGTNTGGCCNGCNYTNCARAGYTAYATHAARACNGGNGAYCCNAAYATGYTNTCNACN YTNAARYTNAAYGAYCARTGGACNCARAGYATHTGGTCNYTNGGNAAYACNACN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TTYCCNTCNCAYCAYGCNTAYMGNGAYYTNGAYAAYCCN CARTTYAAY---GCNGCNTCNATHGCNGTNCCNGARGTNCCNAARTAYTCNTAYTCNAGY ATHAARACNGTNGTNGAYGCNGGNATGCARCCNATHTCNCAYCARACN------YTNCAR CAY---------CCNACNAARGCNCCNCCNGGNTCNGCNACNYTNTCNAARMGNCCNACN GTNAGYAARGCNCARCCNYTNCCNGCNAARYTNCCNGTNGCNGGNATGAARMGNMGN--- CARGTNCCNCCNCCNGARGTNGGNGGNCCNYTNAARYTNGGNAARGGNGGNGGNCCNGGN GTNCARATHGGNATHGGNGAYYTNTCNCARGTNAARMGNTCNAAR------YTNAGYATG ------CCNGARGAYATHGARATHATHGAYYTNGARGAYAGYTCNGARTTYGTNAGYCCN YTNCARGGNTTYMGNYTNATGGTNACNAAYYTNTTYACNGGNGTNACNCAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNAARMGNATHTCNTTYTAYGAYATHGTNYTNAAYGARYTN YTNTGYYTNYTNAGYACNGGNAAYACNGGNAGYGCNAARGARYTNCAYCARGARTTYYTN AARGCNAARGCNACNTCNAARTAYGCNCCNGGNAARMGNGAYGARGTNAARYTNYTNTTY AARGCNTAYCARGGNYTNYTNYTNTAYYTNGAYTGGAARGTNATGGARAGYAAYGARCAR GCNACNGAR---CARAARAGYTTYATGGARGAYATGTTYTCNYTNAGYCARYTNGARGAY CCNTCNAARGAYYTNGCNAARAGYGCNTCNGAYYTNYTNTCNTCNGTNYTNGAYTGYTCN GGNGTNTGGGAYATGTTYATHACNMGNYTNGTNGARATHCAYGARTAYTAYGAY------ GARCAYGARCARGAYGTNYTNAARMGNTAYMGNGARAARAAYCCNAAYAAYCCNAAYGCN CAYYTNTAYYTNCAYMGNTTYTGYGARMGNAAYGGNCAYTCNGARYTNAGY---YTNGCN TGYYTNCARGAYATHATHAARYTNGAYCCNTGYAAYCCNYTNGTNCCNACNYTNTTYCAY CAYYTNGARAARMGNGAYCCNGGNGCNGTNTGYYTNYTNTTYAAYTAYYTNGAYTTYGTN CAYTGYAARGAYGAYAAYATHGTNTGGGARATHYTNGCNGAYMGNYTNCAYCARTTYAAR TCNTCNGAYCARACNYTNCARGTNGTNMGNCARTGYTGGGARTCNMGNAARGAYTGGTGG CCN--------------------------------------------------------- ---MGNAARTCNCCNAAYTGYTCNACNTGYAARGGNATHGTNGAYAAYTTYAARAARGGN YTNTCNGAYACNAARAARTCNAAYTAYGGNGGNGGNAAYACNAARTGGGARGARAARTCN YTNGGNTCNTAYGCNTAYAGYGARGTNMGNYTNGTNGARATHATGGARAARYTNTGYGAR AGYGTNGGNAGYGARTGYCAYACNGTNYTNGARGARCAYGARGAYYTNATHGARMGNTAY TGGTTYAARGARTTYGCNCARAARAARGAYACNGAYYTNCAYACNTAYYTNTGYATHGAY TAYATGAARGCNTGYTGYCCNAARAAYACNTAYGGNAARGAYTGYACNCCNTGYMGNGGN GGNGTNGAYAARCCNTGYACNGGNAAYGGNAARTGYAARGGNGARGGNACNMGNGARGGN AAYGGNAAYTGYGARTGYGAYTCNGGNTAYCARGGNGAYATGTGYGAYTCNTGYAARGAY GGNTTYTAYGARCAYACNAARAAYGARACNGAYACNGTNTGYAARGTNTGYCAYATHTCN TGYACNGAYATHTGYTCNGARGARGGNCCNACNGGNTGYGARGARTGYAARGAYGGNTGG YTNGTNGAYGARGARAARGGNTGYGTNGAYATHAAYGARTGYGAYGARGAYCCNTGYGAR GAYCAYCARTAYTGYACNAAYACNCARGGNTCNTAYTCNTGYTTYTCNTGYGAYGAYGCN TGYGCNTCNTGYAARGGNCCNGGNCCNGGNAARTGYAAYAAYTGYCARGARGGNTAYAAR ATGAAYGARGCNAARGCNAARTGYATHGAYGTNAAYGARTGYAARGARAAYCCNGAYYTN TGYACNGCNGARAAYGARATHTGYYTNAAYGTNCCNGGNAGYCAYAARTGYTCNTGYAAR AAYGGNTTY---GARMGNCARGAYGAYAARTGYGTNCCNGARCCNAARGAYGARGAYAAY AGYTCNACNGARAGYAARGAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARTTYATGACNTAYAAYGCNTCNCCNGTNTGYCARGAYYTNCAR ATGAARGTNATGGARTGYTAYCARACNAAYCCNAAYGARATHYTNACNTGYTCNACNYTN GTNAARGCNTTYACNACNTGYGTNGARMGNGCNMGNGTNGCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYGGNAARTCNAAYGGNGAYYTNTTYTTYAAYCARGGNYTNGCNTAY GARGGNYTNMGNGAYATHCARAAYTCNYTNCARTCNTTYCARGARGCNTTYAAYGARTAY TGYTCN---GARMGNAAYGARGCNATGAARGTNGARTCNYTNYTNMGNYTNGTNCARYTN AAYAARGAYATHAARAARTAYGAYTCNGCNAAYAARYTNATHGAYGAYYTNATHCCNYTN TAYGARAAYTCNCARAAYYTNGAYGGNYTNYTNAARGCNYTNGTNGAYAARGCNACNYTN YTNYTN---YTNGGNAARGARGARGARGCNAARGARCARGTNGARAARTCNTAYGAYGAR ATHCARAARACNCARTTYTCNGCNCARCAYGCNAARGTNATGATHGAYGCNTCNYTNGTN YTNAARMGNYTNAARGAYTTYGAYAARGCNYTNGAYGTNYTNGARAARGCN--------- ---MGNTAYGTNGTNGAYGAYCCNATHCARGARGCNATHATHTAYCARAAYYTNGGNGCN GTNCAYAAYYTNAARAARGARTAYGAYGARGCNATHATHCAYCAYAARGARGCNAGYGAR AARTTYGGNAARYTNGARAAYMGNMGNAARCARGGNCAYTGYTTYCAYAAYATGGGNTTY GCNTAYAGYCARAARCCNGAYTAYGARAAYGCNAGYGARTTYTTYYTNYTNGCNYTNCAR ATGGCNAARGAYTCNGGNGAYACNACNTCNCARTGGCARAAYYTNGARTCNYTNGGNGCN GTNGCNTTYAAYAARGGNGCNTAYMGNAARGCNGARGARTGYTAYAARAAYGCNYTNACN GCNYTNGCNCARTCNTCNGARTCNAARAAYTCNGARGCNCARGARMGNATHTTYCARAAR YTNAARTCNGTNGTNCCNYTNCARGARACNAAR--------------------------- ---ATGYTNGARTCNAARAARGCNTCNCCNGARGCNGAYGTNACNGARATGACNGARAAY GGNAARGTN------------------------------------GTNYTNMGNMGNAAR GGNTCNCARACNMGNTAYYTNAARGTNMGNMGNTCNGGNACNYTNCARAARTTYCARAAR GTNGCNYTNGGNYTNGAYAGYAARGCNGAYMGNYTNAARGTNGAYMGNGTNATGATHTGG AAYGARTAYGARGCNTAYGTNGTNCARTAYAARCARATHGCNGTNTCNGCNTGYGGNCAR ACNGCNGTNYTNAAYGTNATGAARGCNYTNAARTTYAAYTGYGAYAARGCNGCNGTNTGY AARGTNATHAARACNAGYYTNMGNAARGARGAYGCNGAYATHCCNGARTAYYTNTTYTCN MGNGCNTGYGCNGGNACNACNGCNGTNGARYTNATGGARGGNGTNGARAARYTNAGYAAY GGNACNGTNGGNGGNMGNTTYTTYCAYTTYTGGCCNCCNMGNAARGTNAARYTNYTNCAR TGGYTNGCNTAYTGGATGAARMGNGGNGCNATHCCNGTNGCNACNYTNAAYYTNCARCAR GGNCCNCAYTCNATHTGGCARATHCCNGAYTCNTGGCAYCAYCARATGGTNTAYGGNGTN AGYCAYCARGGNYTNTAYYTNACNAAYCCNYTNGARATHGTNTCNGARMGNTCNGCNATH AARCARYTNTGYAGYGAYTCNGTNYTNYTNGTNMGNMGNCAYGAYATHGTNACNMGNTTY MGNGAYACNACNGAYYTNGGNCARYTNYTNGARCAYCCNGAYCARMGNTGGATGTCNATG AAYGTNYTNGGNCARGTNGTNAAYGTNYTNMGNGARTTYAAYATGCCNACNGTNCCNGGN TAYMGNYTNCARGTNACNTCNCAYATHGCNATHCCNGCNTTYTAYMGNGCNGGNATHACN YTNTAYATGTGYAARGAYAARCCNGCNTGGTCNAGYYTNGTNAAYGCNCCNGAYYTNCCN YTNGCNCCNGAY------------------------GTNYTNACNGAYGTNMGNTAYAGY AARCARGTNTCNCARGCNGTNAARYTNGGNTAYTCNGARGARCAYGCNAARGCNGCNYTN ATHATHAARGGNCCNGAYTGYGAYYTNAAYGGNYTNYTNGCNGARYTNGTNMGNAGYCAY GAYTCNTAYTCNTCNACNYTNTCNTCNTCNGAR------------------TGYYTNGAY TCNGGNYTNMGNYTNTCNCCNCCNYTNYTNAGYGGNCCNMGNGARGARGARAGYAGYYTN YTNCAYGAYACNAARAAYAGYGAYAARGARGARAAYYTNMGNCAYATHATHATHGAYGGN AGYAAYGTNGCNATGGGNCAYGGNCARTCNGTNTTYTCNTGYAARGGNATHAARATHGCN GTNAARTGGTTYAARGARMGNGGNCAYAARGARATHACNGTNTTYGTNCCNCARTGGMGN AARGARACNTCNMGNCCNGAYGCNCCNATHACNGAYCARGAYATHYTNATGGARYTNGAR AARGARMGNATHGTNGCNTTYACNCCNGCNMGNMGNGTNAARGGNMGNMGNGTNGTNTGY TAYGAYGAYMGNTAYATHYTNAARYTNGCNGCNGARACNGAYGGNATHGTNGTNTCNAAY GAYATHTAYMGNGAYYTNGTNAAYAAYAAYGARCARTTYMGNACNGTNGTNGAYGARMGN YTNYTNATGTTYACNTTYGTNAAYGAYMGNTTYATGCCNCCNGARGAYCCNYTNGGNMGN YTNGGNCCNTCNYTNGAYGAYTTYYTNMGNAARGTNCCNGCNGARCCNCCNGCNMGNCCN CARGARTGYCCNTAYGAYAARAARTGYACNTAYGGNAAYAARTGYAARTTYTAYCAYCCN GARMGNGGNTTYATGCCNCARAARTCNATHTCNGARACNATHAARGARMGNAAYAAYGTN AARYTNCARGARATHGCNACNAARGCNTCNGARMGNGTNAARMGNACNAARCARAARYTN ATHMGNACNMGNTCNYTNATHCCNGGNGARATHCCNCCNACNCCNCCNGCNACNGAYTCN AAYAARMGNAARCCNAARYTNGGNCAYTCNAARTCNGTNTCNGGNGARYTNGAYTAYYTN ACNGARTCNMGNAARAARYTNGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ACNYTNACNGARGCNGAYTGGAARAGYATHAAYCARTGGYTNGTNAAYCARATGGTNGAR AGYATHACNCARAARATHAARCCNAAYGTNCCNGAYGTNTTYGCNATHAARTTYTCNCCN GTNGARATHGCNGAYATHATHGAYGAYTCNGTNCARGAYYTNATHAARTCNTAYCCNMGN TGYGCNTTYCAYTTYAARMGNCARGGNGGNAARTTYAARAARAARAARGGNTAYGCNGAR GTNTAYTTYCCNMGNYTNGARACNATHMGNGAYTTYGTNAAYAARYTNACNCARYTNGAR ATHTCNGARMGNMGNYTNGARATHTCNATHACNTCNATHAAYCCNAAYAARGARAAYGAY GTNTAYTCNTTYATHATHTCNYTNAARAARAAYGGNTTYYTNAARAARYTNYTNCARAAY AARGAYGAYCCNTAYGCNAARGTNYTNGGNAAR---------GAYGGNGGNATGYTNGAR GTNAAYGAYGTNCCNMGNAAYGCNAAYGCNACNTTYYTNAARAAYATHTTYCCNTTYACN ACNTTYGTNGCNATHAGYAAY---------AAYAGYTCNAGYTCNTCNGARTTYTCNAGY ACNATGTTYGTNCAYTAYAGYCAYAARAAYTGGCARGARGCNGTNYTNGCNTGYTGYTCN CARTTYAGYATHAAYGGNCAYYTNYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNCARAARCARYTNGGNYTNACNCCNGGNACNGARYTN CCNATHGGNACNAARCCNATHGGNAGYMGNGARAARTTYGTNMGNCARATHYTNTCNGAY MGNGARGAYGARTTYACNGAYATHAARTCNTTYAARGTNTTYTGYGGNTCNTGGAAYGTN AAYGAYCARTCNCCNGCNGAYCCNYTNCAYAARTGGATHGTNGTNGAYAAYGAYCCNCCN GAYATHTAYGCNATHGGNTTYCARGARYTNGAYYTNAGYAARGARGCNTTYATHTTYTCN GAYTCNGCNAARGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNCAYCARATH TAYYTNGAYGARCAYTTYGGNACNATHAAYAARGGNAAYGARGARGARAARAARAARAAY GCNGAYAARAARGCNGCNATHGGNTTYGTNTAYGARGAYAGYACNCCNGTNGARAARAAR GARGCNGARGARGARGARGARGARGARAGYGAYGARGAYYTNGARACNGCNGAYYTNGAY GTNACNATHGAYGTNGAYACNYTNACNYTNGAYCARGCNMGNGARATHAAYYTNTGYGCN ACNCARTAYGGNATGAARGARGAYGAYTTYGTNMGNYTNYTNAARMGNGAYAARGARGAR YTNGARGCNYTNAARGARGCNMGNCARYTNGARGARGCNAARGCNCARTTYTCNGGNMGN AARTCNMGNMGNGARMGNMGNGCNATHAAYGARMGNAARCARAAYCCNYTNMGNTTYAGY MGNCCNAGYTAYGCNGCNMGNGARAGYCCNAARTAYGARCCNTAYMGNMGNCCNGGNTCN TCNTCNMGNTCNMGNTCNMGNTCNMGNTCNMGNTCNTCNGARGARGTNGARYTNAARTTY ATHACNAGYTTYGGNAAY---GARAGYGAYGARGAR------GGNGTNGTNCARGGNCCN TCNYTNCCNGCNCCNCARAARCARGARAARAGYAARCAR------AARACNTCNGARTCN TCNAARTGYGARACNCCNTGG---YTNTCNAARTCNMGNGARAGYCARCCNMGNGCNAAR TCNTAYAARMGN---MGNTCNMGNTCNGGNTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AGYACNYTNCCNGAYACNTCNATGTCNTGYCARCAYATHMGN TCNTGYYTNGARGARYTNACNMGNGTNYTNGCNTCNGCNTGGATHACNGARYTNCCNCCN ATHGAYGCNMGNGGNCAYTTYTAYGAYCCNATHYTNGTNGAYCARAAYGARATGYTNAAR MGNGARGCNACNATGYTNMGNTCNAARTGYGAYGTNYTNGAYCAYACNGTNAARGARCAR AARGGNMGNYTNAGYGCNTCNGAYGARMGNCARAARAAYTGGGARAARTCNATGTGYMGN CARGCNACNATHAGYAGYAARMGNTCNYTNAGYTGGTCNGARTCNTGYGAYGAYGTNCAR TAYTTYCCNCARCAR------------------AGYMGN------------AAR------ ------ACNGARATHGARGARGARGARATHYTNCAYTAYAARAAYTGYCARATGYTNGAY CCNCARAARAARAGYGARTAYGAYTGYATHAARMGNATGTAYGCNAAYATHYTNTAYMGN TGGGGNTTYYTNAAYCARAGYGCNCARGTNAAYAARCAYACNGTNAGY---TAYAARACN GCNCAYGARATGGARTTYACNGTNCCNTGYCARMGNTGYGARGCNCCNGTNGCNAARGCN GARTGYCAYMGNTGYCAYTAYYTNGCNATGACNTGYTCNATHTGYCAYCARGGNGTNMGN GGNGARGTNAAYACNTGYYTNTGYTGYGGNCAYGGNGGNCAYGCNTCNCAYATGCARYTN TGGTTYAAYCARTTYAAYYTNTGYCCNGCNGGNTGYGGNTGYGCNTGYYTNGARAAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATHAARTGYYTNGARAGYAAYATH GARGARYTNAARTTYGCNNNNGARTCNGARGARAARMGNYTNTGYAAYYTNGTNGARGAY TGYCARAARMGNTTYGTNGCNAGYCARAARCARGTNAAYGAYYTNGARGAYGCNYTNYTN GTNTGYMGNAAYGARGTNTGYAAYCAYYTNAAYACNATGGAYGARATHAARMGNCARTGY CARTTYGARATGGARCARMGNGAYGCNTGYATHAARAARYTNAARGARGAYYTNMGNMGN ACNGTNGARGARYTNAARTGYMGNATHGARGARAAYGGNTCNYTNGARAARTCNATHTCN GAYYTNAARAAYAARYTNCARCARATGTGYTGYCARYTNAARGARGCNGAYAAYAARATH ATHTGYTTYACNGARAARYTNMGNGAYATGGARAARYTNATGATGAARGARAARGCNGGN TGGATGAARGARTCNGARGARYTNGARMGNMGNYTNCARCARGCNTGYAAYAAYYTNACN GTNGCNAAYAAYGARATHACNCARYTNAARTTYACNATHCARGARMGNAAYAGYCARYTN GAYGCNYTNCARATHGARAARAAYTGYYTNGGNMGNGAYYTNTCNAARTGYMGNGAYGGN ATGCARTGYYTNAAYGAYAARGTNTGYAARATGGARAARGAYAAYCARGARYTNTGYMGN CARYTNCARCARAARATGGAYTGYATHMGNGAYYTNGARGCNATGATGMGNACNAARGAR CARGARYTNAARTGYATGGCNAARTGYYTNGAYGAYTTYCARATGAARGCNGCN------ ---AAYACNCCNGTNGAYAGYATGGCNGARYTNAARGARYTNAARGARCARYTNGARAAR TGYMGNGTNGARYTNAARTGYAARAGYACNYTNYTNTGYGARTGYGARTCNTCNTAYAAR CARGTNCARGTNATGYTNGCNGAYAARGARGAYGARGTNAGYYTNYTNAARTGYCARYTN GARAAYGTNGAYGCNAARYTNAARGARMGNYTNTCNMGNGTNGARGARYTNGARAARGGN ATHGARACNYTNCAYAARGAYATGGARMGNMGNATGCARMGNGTNGAYGARCARYTNAAR AARTAYGARTCNGARYTNACNGAYMGNGCNAARCARATHGCNGAYYTNGAYGAYTGYYTN AGYMGNTGYCARTAYAAYYTNAAYAGYAARGCNGAYGARYTNAGYCARCARGARCARAAR AAYCARMGNYTNTGYGTNGARYTNCARGCNGCNGCNTGYAARYTNAARGARACNGARGAY ATGMGNGAYAAYYTNAAYCARTCNYTNAAYGAYAARAARATHGAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AARGCNAAYGAYCAYATHATHATHCCNAGYAARGAY TTYACNYTNYTNACNTCNCCNTCNGCNTTYACNACNTAYACNTTYAAYACNCAYCARGCN AARCAYACNTTYTGYTCNACNTGYGGNGTNCARTCNTTYTAYACNCCNMGNAGYAAYCCN GAYGGNMGNGCNYTNAAYGTNMGNTGYYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MGNGCNTCNAGY TTYGARGAYACNMGNTGYAARTGYGTNTGYGAYAARACNTAYGAYGCNACNGGNAARGAR ACNMGNGCNGTNTTYTTYAAYACNACNMGNAGYGARCARTGYGAYTGYGARCAYGTNGTN CAYCCNYTNGARCCNACNATHTCNTGYACNMGNTGYYTNTGYMGNACNCARACNMGNAAY ACNACNACNATHAARGTNGTNGTNATHTTYATHATHTGYGTNGTNYTNYTNYTNTTYGTN TAYATGYTNTTYYTNYTNTGYYTNGAYCCNYTNATHCARMGNMGNCCNTCN---TCNTAY CARCARCAYACNAAYGARGARGTNAAYATGGARGAYYTNTCNTCNGCN---MGNTCNGAR GTNGCNGCNACN---------GGNGGNGCNGCNGGNCARTCNGCNGAYYTNAGYGCNMGN CARMGNTCNYTNYTNAAYYTNGTNACNAARGARCARAARAARTGGAARGGNACNGTNMGN GARCARMGNMGNAAYATHTAYGAYACNCAYAGYATGYTNAAYACNTCNGAYTCNACNCCN TCNACNGCNAARCCNYTNCARACNTTYGGNGTNATHGCNGAYGTNCARTAYGCNGAYTGY GARGAYGGNCAYAAYTTYGCNMGNACNMGNACNMGNTAYTAYMGNGGNTCNYTNAAYYTN YTNAAYAAYGCNGTNAAYGAYTGGAARAAYTGYACNAGYCCNYTNGCNTTYGTNATHCAR YTNGGNGAYYTNATHGAYGGNAARAAYACNAARGGNGTNGARGCNAGYAARMGNGCNYTN CARACNGCNYTNCARCCNYTNAARTCNYTNAARGTNCCNYTNTAYCAYYTNYTNGGNAAY CAYGARTTYTAYAAYYTNGAYMGNTCNTTYTAYYTNACNTCNCCNYTNAAYTGYGCNMGN TCN------------------------GAYAAYACNAARGARGAYCARYTNTAYTAYACN TTYYTNCCNCAYCCNAARYTNMGNTTYGTNGCNYTNGAYACNTAYGARGTNAGYGTNATH GGNTAYGCNGAYAAYACNGAYAAYGARAAYTAYMGNAARGGNGCNGARYTNTTYATGCAR CAYAAYAAYYTNGARAAYCCNAAYGAYTCNTCNCAYYTNGARGGNTTYGARAARMGNTGG ACNGCNTAYAAYGGNGCNGTNAGYAARYTNCARATGCARTGGYTNGCNGARGTNYTNTCN AARGCNCARGCNMGNGARGARAAYGTNATHATHATHGGNCAYGTNCCNATHYTNGGNGAR YTNAAYGAYGAYAAYGTNATHAGYYTNYTNTGGAAYTAYGARGARGTNYTNCARGTNYTN CAYAAYTTYAAYTGYGTNGTNGGNGTNATHTGYGGNCAYGARCAYCARGGNTAYCARACN GTNGAYMGNCAYGGNATHCARCAYATHACNTTYCAYGGNATHATHGARACNGAYCARGAY AGYAAYGCNTAYGCNAARGTNCAYYTNTGGAAYGAYCARATHACNGTNAAYGGNGTNGGN GTNATHCCNAAYTTYTCNATHCCNYTNYTNTTYCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN GAYGTNTCNCCNGARGCNTGYCARYTNACNMGNGARAAYGCNGCNTCNYTNAARYTNGAY MGNMGNGTNACNGTNATHGARGGNGAYTTYTTYTGYGARAARGTNCARMGNAAYYTNMGN GAYYTNGGNCCNTTYAGYATGYTNGTNAGYAAYCCNCCNTAYATHACNTCNCARGARATG AARACNYTNCARCCNGARATHACNCARTAYGARGAYCCNACNGCNYTNGAYGGNGGNYTN GAYGGNYTNGAYATHGTNMGNGARATHYTNYTNAARGCNCCNGAYATGYTNGTNCCNCAR AGYTCNATHTGGYTNGARGTNGGNCCNCARCAYCCNCCNYTNGTNAARTCN---YTNGTN CARAAYGGNYTNYTNCCNAARYTNGAYTAYATHAARACNGARTCNGAYYTNTTYGGNAAR GARMGNTTYTGY---GGNTCNCCNGARGTNGGNGCNGTNAAYTTYAAYATHYTNCAYACN YTNYTNCAYGCNATGATHCARAARYTNAAYATHCARGARGTNAARGCNGAYGTNAAYGAR CAYGAYMGNGARYTNYTNTCNACNCAYGCNGGNCAYMGNGCNTTYTCNACNTTYAGYYTN GGNGARGAYTCNTTYTCNGARGAYAAYGTNAGYGARAARTCNAGYTAYGTNCCNTCNMGN AARAGYCCNTAYCAYCAYYTNGARAARGARGTNTCNGARYTNAARMGNCARATGGARGAR YTNAAYAARYTNCCNAGYAAYGARCARYTNYTNGGNAARYTNCAYGGNAARGARAAYGAR MGNCCNATHTCNGAYATGTGGCARTAYATGCARYTNAARAARMGNGTNGAYGCNAAYGAR GARGGNATHGGNAARYTNATGTCNYTNATGGARGAYYTNATGAARGAYGTNAAYGAYYTN AARGAYGGNCARAARTCNYTNYTNGARCARYTNAAYGGNATHAAYYTNGAYGAYATHAAY AARMGNYTNGAYGGNATGGAYAGYYTNYTNAARGAYYTNAAYGAYMGNCARGAYAARYTN GAYAARMGNGTNTCNAAYATGCCNTCNTTYGAYGAYYTNGAYCARTAYTTYAAYCARTAY GTNACNTGGCCNGGNYTNGARGAYGCNYTNAARGGNGTNMGNYTNGAYTTYGARAAYYTN CARCCNATHCAYGARGARMGNGTNGTNATHGARYTNGGNACNCARACNGARACNCCNAGY MGNCCNACNTCNGCNMGNCCNACNTCNMGNGCNTCNTCNGCNMGNACNGCNGGNCCNAGY CARGARYTNYTNGAYATHYTNGARMGNYTNGGNMGNYTNAGYCARTCNCAYGARCARYTN AARYTNMGNGTNGAYGARYTNGARAARYTNYTNGARYTNAARGCNAAYAARGGNGAYYTN GARGGNYTNGGNATHTCNGAYGAYYTNATGTCNACNYTNAARAGYYTNCARGAYGARYTN AARGCNYTNCARGAYGGNMGNTTYAARGAYGARGCNGCNATGMGNMGNYTNCARGARATH GTNCARAARYTNCARGCNGARATHGAYAARYTNMGNAAYTCNATGGARGCNGTNYTNGAR GARAAYGCNCARMGNGTNAARGARATHCARGAYYTNYTNCARTAYTGYGAYAARYTNGAY AARACNAARGCNGAYAARGAYTAYGTNGAYATGGARGTNGARGTNAARGCNGAYMGNAAR CARYTNGARGGNAARGTNAAYCAYAGYYTNTTYGAYAGYACNACNAAYGARYTNAAYMGN ATGATHAARGAYATHYTNGAYAARYTNAAYGGNCARGARGARGGNTGGAARGCNGCNYTN GCNAARGCNATGGAYGARYTNGAYGGNAARYTNGAYMGNYTNGARYTNAAYAAYYTNAAR GARTGGYTNGARAARCARYTNAARGCNYTNAAYAGYAARATHAARACNATGGGNCCNGGN TGGCARATGGAYGAYGARGCNGCNGGNATGAARAARCARYTNATHCARMGNTTYCAYTGY YTNTCNTGYGAYAARCCNGTNGCNGTNATGCCNCAYGGNCCNGTNCCNTCNATHCCNGCN AAYTAYGGNYTNCCNAARTCNAARTCNCCNMGNCCNTAYACNACNTTYGARYTNGAYCAR ATHMGNCARCAYGCNMGNTTYYTNGGNATHAAYCCNGARGCNGAYGAYTAYTAYGCNACN ATHMGNCARTGYGGNGGNAGYCAYACNACNACNCAYCCNCAYAARMGNACNTCNAARYTN AAYAAYYTNGGNCARYTNTTYMGNGARGARGARACNATHTAYCCNYTNAARAARGARGAR GTNGAYGTNCARGGNGCNGAYGGNCAYATHTAYMGNGGNMGNATGGAYTCNTCNMGNATH GARGCNAARYTNCCNACNAAYTTYCCNMGNCARCARYTNTAYACNCCNACNTAYCCNGAR MGNAAYACNCCNTCNCCNCARCCNCCNAARMGNCCNYTNTCNGCNMGNGTNCCNMGNCCN TCNTCNGCNMGNCCNGGNTCNAAYTCNCCNCCNTCNCAYGGNCAYCARCCNATGCCNCCN CARGARGGNGARAGYGGNGGNGCNCCNTCNAAYAGYCARGCNGGNGGNTCNMGNGCNACN ACNCCNYTNCARGARGAR------------------------------------------ ------------------------------------------------------------ TCNAARYTNAARACNGTNCARAAYGGNAGYCAYGARTCNATGGAYAGYCARATGAGYAGY TCNAGYGCNAGYACNGARAAYYTNTCNYTNTCNAAYAARGAYGGNAARGARGCNCAYGAY AARATHYTNCAYCARMGNGTNCAYTTYCARGTNTAYTAYYTNGGNTGYGTNCCNGARATH AAYATGACNATHTCNAARAARMGNGAYACNGAYGCNCARYTNATHGAYYTNYTNGARGAR AAYCARATHGARGGNYTNYTNCCNATHYTNGCNACNGARCAYAAYAARGTNGTNATHAAY GTNTCNMGNCAYGGNATHAARGTN------YTNGCNGGNAARGARGTNYTNCARMGNCAY CCNYTNCAYACNATHGCNCARYTNACNGARTAYACNGAYGGNTTYAAYATGGARAAYATH GCNYTNAARATHGGNCARGTNGGNAARAAYGTNTAYCARTGYCAYYTNTTYCARTGYCAY TCNGARTGYTCNATGATGAARGAYTTYGTNATHGGNGTNTGYYTNGCNGTNTCNTCNTCN GTNTTYATHGGNTCNAGYTTYATHYTNAARAARYTNGGNYTNYTNMGNTAYGCNMGNMGN GTNTCNGTNMGNGCNGGNCARGGNGGNYTNGGNTAYYTNMGNGARTGGATGTGGTGGGCN GGNATGATHYTNATGACNACNGGNGARTTYGCNAAYTTYGCNGCNTAYGCNTTYGCNCCN GCNACNYTNGTNACNCCNYTNGGNGCNYTNAGYGTNATHGTNAGYGCNATHYTNTCNGCN AARATHYTNAAYGARAARYTNAAYATHYTNGGNAARGTNGGNTGYGTNYTNTGYGTNYTN GGNTCNACNYTNATGGTNATHCAYTCNCCNAARGARCARGARGTNCAYGAYGTNGARGAR YTNATGYTNAARATGAARGARCCNGGNTTYATHGTNTAYGCNYTNYTNYTNYTNATHACN TCNATHGTNATGATGGTNTAYTTYAGYCCNMGNTAYGGNCARAARAAYGTNYTNGTNTAY ATHACNATHTGYGCNACNYTNGGNACNTTYACNGTNATGGGNTGYAARGGNGTNGGNACN GCNATHACNGCNACNGCNMGNGGNCAYAAYGARTTYAARAAYTGGYTNACNTAYGTNYTN YTNGGNGTNGTNYTNATHTGYATHYTNYTNCARYTNAAYTAYYTNAAYAARGCNYTNGAY ACNTTYAAYACNGCNGTNGTNACNCCNATHTAYTAYGTNTTYTTYACNACNTGYGTNATH ATHGGNTCNGCNATHYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AARTAYAAYTTYMGNATGAAY ATHTCNGTNGCNGARMGNYTNCCNGCNAGYGGNCCNMGNTGGTAYAGYGTNGCNATHGTN ------------------------------------------------------------ ------------------------------------------------------------ ------GAYTCNGTNMGNYTNGCNMGNMGNAAYAARGAYATHTCNTAYGGNAARAAYACN GAYGCNTAYMGNAARTAYGTNGARACNATHCCNMGNGARYTNMGNAGYGAYGAYYTNYTN MGNCAYCCNMGNACNCCNCARAARAAYMGNMGNTGYAGYMGNMGNTCNTGGGAYTCNCAR GTNMGNMGNTGGAARMGNCARYTNCAYATHTGGGCNGCNGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNGARTCNGTNTGYCAYGARYTNAAYATGTCN GARATHCARATGCCNCCNCCNATHAARACNGARGAYGTNCCNYTNCCNCCNGGNAGYCCN ACNAGYCARCCNTCNGARAGYCAYACNGAYGAYAARAAYGTNGTNGARGAYYTNAARGAY ATHYTNYTNCCNTCNGARCCNCCNCCNCCNGARAARAGYGCNAARGARGTNGCN---GAR GTNGGNAARGGNAGYGTNTGYTTYTCNTTYAGYAARACNACNAGYAARATHGCNGTNACN TCNGCNTTYAAYCARGARGARCCNGAYACNGTNGARYTNCCNCCNCCNMGNCCNYTNACN YTNATGGAYAGYATHGARGARGARAARMGNGTNATGCARYTN---GGNTCNGGNGAYGCN ACNACNAAYTCNGARAGYACNGGNTCNGCNACNTCNACNACNACNACNACNACNACNGCN TCNAAYACNAGYACNACNCARCCNAGYAAYAAYCCNMGNYTNYTNGARAAYTTYGTNAAR GTNAARYTNAARCARGARCCNCAYAAYGARATHGARTGGCCNGCNGARACNYTNAARTAY ACNAARACNMGNCCNTCNGTNCAYTAYGCNTGYAAYATHTAYCAYTTYGAYTTYAAR--- ACNTGYCARGAYGGNGGNYTNACNGARGARACNGCNAARGCNCARGGNGARAGYGGNAAR ACNAARGCNGGNTCNGARGARAAR---------AGYAARACNGGNAARGAYGGNAARACN MGNMGNAARCAY---YTNCAYAARAARMGNMGNCAYAARAARAGYGGNAAR--------- AAYGGNGAYGGNGARGTNAARGARGGNGARGARAARAAYCCNGARGGNAARGCNGCNGAR GGNGAYGCNGGN---ACNGARAARAARAARAARAARAARMGNAARAARCAYAARCAYCAY MGNMGNAAYAARAARGARGARGARACNGGNGARGCNGGNGTNGARGGNGCNTCNAARGAR GGNGARGAY------GAYCCNAARTCNAARAARAARTCNMGNMGNAARMGNAGYCAYMGN TCNAARGARGAYACN------GARGARCCNAARGARGGNGARGARAAR---------AAR AGYGGNGARCARAGYGGNAGYGCNGTNCCNAAYGGNGARAARAARTCNCAYMGNMGNAGY AARAARMGNAARMGNAARCAYMGNMGNCAYGGNTCNACNMGNTCNGARAARGCNAARGCN YTNAGYGCNTCNGARAARGCNAARGTNGARAAYAAYATHGAYAGYGTNAAYGCNAARGAR CCNAARGTNAARATHGAYTAYGAYGARGTNGARGARAGYCAYATHCCNACNGARGAYGAR CARGAY---ATHGGNGARCCNAARATHAARMGNYTNMGNMGNTCNAARAARMGNCAYMGN MGNACNTCNAGYCAYAAYGAYGCNGGNGGNGAR---GTNATGAARACNGARGAYYTNGGN AARGAYGAYYTNAAYTTYACNTTYAARACNCAYAARAARYTNAARGARGARCCNYTNATH GCNACNGARAGYYTNAARGCNAARTGYGCNGTNCCNATHAARAARGAYGTN--------- ------GAYACNCCNTCNAARAGYAARACNCCNAAYGGNGAYGTNTCNGCN---MGNAAR MGNGGNGCNAGYGTNTCNAGYTCNGARGCNATHCCNCCNGCNAARGTNGGNAARCCNGAY AARTGYGAYGTNACNGARGAYACNTGGAGYAARATGGARGGNYTNTAYGARAARAAR--- GARGARGGNTCNAARAGYAARTGGGAYACNAGYGAYAGYGARGGNGARGAYGCNYTNCAR AARACNYTNGAYCCN------------AGYYTNTCNGAYGARGARAARTCN---AARYTN ---CARGTNAARCCNGTNAAYGGNAARATHCCNYTNGCNAARACNYTNYTNACNCCNAAY AGYYTNYTNGGNAAYCAYGTNATHAARCCNAGYACNCCNYTNAARGARAGYCAR------ ---------------------------------AARGARGGNACNAGYGAYGCNGGNGCN AARGCNGCNGAYGGNATHAAYAARGARGGNAARGGNACNAARTCNCARMGNGARAGYMGN AAYCAYGGNMGNAGYAGYMGNMGNTCNTAYAGYTCNTCNGAYTAYTCNTCNMGNTCNMGN TCNMGNTCNMGNTCNTCNTCNGGNTCNTAYMGNAGYTAYTCNAAYGAYTCNMGNTAYAGY GAYGAYAGYMGNTCNCAYAGYMGNTCNTCNMGNAGYTAYAGYMGNAGYMGNTCNMGNCAY MGNTAY---------MGNMGNMGNTCNTCNTCNAGYCAYGGNTGGMGNAGYTAYAGYAGY MGNTCNAGYTCNAGYMGNTCNMGNAGYMGNTCNTAYAGYMGNTCNMGNAGYTAYTCNMGN TCNMGNTCNMGNAAYMGNCAYMGNMGN---AGYAARTCNMGNAGY---YTNTCNMGNMGN TCNAAYGARYTNMGNAAYATHYTNAARYTNCCNACNYTNCCNCCNTCNGTNACNACNYTN ACNGTNGCNCCNGTNACNGGNTCNGCN--------------------------------- ------GGNGCNGGNAARAGYAGYGGNGGNGGNCARCCNGAYGARATHCCNYTNCCNGGN AARGAR---CCNGCNCCNGCNCCNACNACNCARGCNGARAARGTNAARGARGARAARTCN GTNYTNACNGAYATHCCNYTNCCNACNTCNGCNGAYAARGTNAARGARGARCCNAARGAY GCNTCNGGNGCNACNTCNGCNGGNACNGTNACNACNACNGCNGCNGGNCARACNGCNACN ACNACN---------------------ACNACNAGYACNGCNGAYMGNGGNGGNGCNGGN GCNGCNAGYGCNGTNGARGGNACNGGNGAYGGNACNGCNGCN------------------ ------------------------------------------AAYGCNGGNGARCCNGTN GCNTAYGAYCARCAYAAY------CAYATHGGNTAYCARTCNCAYGAYCCNTCNTTYTGY GARGAYACNGGNTAYGAYAGYTTYGARTTYGAYGGNTCNGGNGARTAYGAYCAR------ ---GGNTAYGAYGARAGYCARGARGARTAYGARTAYAGY---GAYCCNTAYCAYCAYCCN CCNYTNMGNCAYCARGGNCCNCCNGGNATG---CAYCCNMGNGGN---CCNCCNCCNGGN TTYMGNGGNCCNCAYCCNMGNATHTTYCCNYTNGAYGGNMGNTTYGGNCCNCAYMGNCCN GGNATGGGN---CAY------------------CCNMGNATGGGNCCNAAYGGNCCNATG GGNCCNMGNGGNYTNMGNCAYCCNATGGGNCCNGGNGGNCCNATGGGNCCNCAYGGNATG MGNGGN---CAYCCNMGNGGN---CCNCCNMGNGGNCCNCCNGGNATHMGNGGNCCNYTN AAYATGCAYGGNCCNMGNGGN---CCNCARMGNCCNGGNATGATGGGNCCNCCN------ GGNCCNATGGGNYTNGCNGGNCCNMGN---MGNATGGGN---YTNCCNATGMGNYTN--- ---CCNATGCARGGNCARGGN------------CCNCCN------------TCNMGNCCN MGNATGGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CAYACNGTNATHGGNACNCCNTGG CARTTYTCNGGNACNTTYAAYAGYCARGGNGGNMGNYTNCARGCNAARGAYTCNGAYGTN GTNYTNACNGTNGGNATGTAYGCNGTNGCNAARGGNGAYTAYGTNGAYATHTCNGGNGCN ATHTTYACNGAYGTNTCNGARATHMGNAARAARATHGARTAYCCNTTYAAYGARATHYTN GTNTCNCCNGTNGTNGARTAYCAYGCNTCNAAYAAYTAYMGNTTYMGNAAYACNATGGTN GTNAARYTNCCNCAYGCNATGCARGARAAYTTYGAYCCNGCNAAYATHMGNGTNTAYMGN TTYATHACNGAYGARTTYGGNGTNGTNTCNGTNCAYMGNGTNGCNGARAARGGNAARACN AAYCARGTNAAYMGNGAYTCNACNTGGGARAARGAYCCNAARAGYAAYATHMGNATHAAR ACNACNCAYTTYAGYGGNTAYTTYTGYACNACNTGYGARGCN---AARAAYYTNCCNTCN YTNTGYACNMGNGTNTTYGGNTCNCAYGTNCARATHAARCAYAAYMGNMGNGARGTNMGN GTNYTNYTNTAYATHTGGGAYMGNMGNYTNAAYATGAARGAYTTYYTNGARMGNATHMGN AARCARGARTTYAAYAARGARMGNCARYTNYTNGCNGAYATHCARGTNCCNYTNATGGAR GGNGCNACNTCNGAYCAYMGNAARYTNGTNGARTGGGCNYTNGARAAYGTNCCNAAYGAR TCNCCNAGYGAYATHTTYCARTGYYTNATHGAYATGYTNCAYGTNCCNGCNGAYACN--- GAYYTNCARGCNGCNYTNGAYAAYGCNGAYGAYGAYTAYATGMGNACNTTYTAYGTNMGN GAYYTNAARYTNGTNGARGARCCNAGYYTNCARATGTCNAARYTNAAYACNYTNAARCAR AARYTNATGGAYATGYTNAGYGTNGARAARACNGARGAYYTNTGYAARGCNTTYGGNATG ATGGARMGNGAYGTNCAYAAYYTNGCNMGNAARTGYAGYAGYGAYAARGAYGTNAARACN GARYTNGTNGAYTAYTGYYTNCARATGGGNGTNACNAARYTNTGGGARYTNYTNMGNCCN ATHAARCARGAYTAYAGYYTNGAYCARTGGCCNMGNCARMGNYTNGCNGTNGAYYTNAGY GGNTGGATHGTNCARTGYTCNGCNTGYGTNACNTAYYTNTGYTGYMGNGGNGTNTTYTTY MGNGCNYTNAGYYTNYTNTCNYTNGGNATHATHCCNGTNATHGTNYTNGAYGGNCCNAAR GCNCCNGARTGGAARAARMGNAARMGNGGNATHCARTTYTAYMGNATHGCNCARGARTAY AARGARYTNTTYATGGCNATGGGNYTNCCNACNGTNGARTGYGARGGNGARGCNGARAAR AARTGYGCNGARYTNAAYGAYACNTGYATHGTNGAYGGNTGYYTNACNAAYGAYGGNGAY GCNTTYGTNTAYGGNGCNAARGTNGTNTAYAARGGNTTY------CAYACNGAYAARAAR ATGCARATHGARAARTAYGAYYTNGAYGAYATHAARYTNAARATGGGNYTNAAYACNGAR GAYYTNGTNGCNTAYACNYTNYTNAGYGGNGGNGAYATGTGYGAYGGNGTNAARGGNGTN GGNAARGARGCNTTYYTNAARYTNAARGARGARTAYAARMGNAAYGARGTNGARAAYATG ATHTCNMGNTTYCARGAYTGGAARAAYAGYNNNYTNYTNATGTCNYTNGARGARAGYAAR CARTCNYTNTCNCARATGAARAARNNNNNNCAYTGYACNATHTGYNNNCAYCARGGNAAY AARCARNNNCAYATGAARNNNGGNTGYTCNNNNTGYNNNACNNNNNNNTCNTGYAARTCN GCNACNGARNNNNNNNNNNNNAAYATHGARACNYTNCCNCARTGYNNNTGYNNNTGGCAY NNNATHGARGCNMGNGTNACNCCNTTYGARACNGARYTNAARATHMGNCAYATGGCNYTN ACNCARAAYAAYTTYCCNGARGCNGGNNNNATHTCNGARTTYCARAGYCAYGARAAYGAR GCN---TGYGAYGTNGARATGACNGTNAGYATGCCNGAYTGYCAYMGNGTNTGYCARATH ATHYTNGARAARYTNCARTCNAAYGCNAARGTNATGGCNCAYYTNGTNCCNGTNTAYATH AARATGTAYYTNTAYMGNATGYTNGAYGARGTNAAYGCNAARCCNYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHAARYTNGARGGNAAYTTYTTYATHATGGAYTCNGARCARYTNGTN TCNAAYCCNTTYCARGARATGCARCARGARGCNGTNAGYGARGCNCARAARAARAAYACN ATGACNGARAARYTNACNAGYGTNAARAAYAAYGTNTGYGARAAYCAYTTYYTNATHGCN AARGGNMGNYTNGARMGNCARAARAAYCARAARYTNAARCAYYTNYTNGAYAGYTCNAAY AARYTNMGNCAYGARGTNAARYTNYTNGAYYTNGAYMGNCARMGNCAYACNGTNCARATG AARAARMGNATGGARCCNCARMGNGAYCAYAGYTAYGAYGAYYTNCARATHGTNAAYACN GARAARMGNYTNGGNGCNAAYATHGCNTCNTTYTAYYTNGAYAARAARYTNAARTAYCCN ATGMGNYTNMGNTCNATHAAYGAYATHGCNGTNACNCCNACNATHMGNAARGCNMGNGCN TCNATHMGNYTNAAYGAYYTNAAYAARTCNYTNCARGARGGN---TGYTAYTCNMGNTCN GARMGNGCNCARACNGCNAARACNACNTCNACNAAYCCNACNGCNAGYGTNACNATGYTN MGNMGNMGNGGNTCNMGNTCNGCNCCNYTNTAYACNAGYTCNMGNGARGGNACNYTNCCN TCNATHATGGAYGARGARCARYTNCARYTNCARYTNAGYGGNMGNAARGCNGAYGGNCAR ACNCARCARGTNAARTTYGCNGCNAGYAAYCCNYTNAARATHYTNGCNTCNTCNGARGAR AGYGCNAARYTNTTYGCNMGNTCNCAYACNTAYTAYCCNGGNGTNACNMGNGCN------ ------------------------------------------------------------ ---------------------------------TAYAARGTNYTNAARCARMGNYTNAAR ACNYTNCCNGAYAARGTNTGYCAYGARGTNATGGTNCCNYTNGGNAARAARGGNTTYATG CCNGGNAARATHGTNCAYACNAAYGARATHYTNGTNYTNYTNGGNGAYAAYTGGTTYGCN GARMGNTCNGCNAARCARGCNATGGAYATHTCNGAYMGNMGNATHCARGARYTNGAYMGN AARATHAARGAYYTNAARGAYCARTGYAARYTNYTNTCNCCNMGNYTNGAYTTYACNGCN CARYTNAARAARCARGCNGARGGNCARAGYGAYGTNCARGARATHGTNGARGARTAYGAY GARGARAARGARMGNCARTGGGAYGARCARCAYAARGTNAAYGTNMGNMGNCAYAARCAR TCNYTNAARGARAARAARGARAARAARACNGCNGTNGAYATGGCNCARCARACNACNGAY TCNAARGTNTCNGAYGARAARYTNTGGGCNMGNYTNGAYGARYTNGARAARYTNGARGAR GARMGNGGNGARYTNAGYCCN---------------TCNAAYAAYAAYGAYGGNTCNTCN GAYGARGARCAYGCNCARATGTCNAARGAYAARMGNGTNAGYTGGGTNGAYGARGARGAR GTNAAR------------------GARAAYAGYGARGAYGAYAGYGAYGAYTCNATHGAR CAYTTYGGNAGYGAYGTNGARGARGAYGAYGARAARGARCARGAYGAYATHTCNAGYMGN AARGARCCNACNTGYAARACNTTYACNCAYACNAARATGACNCCNGAYACNAARCCNACN GARGTNGGNAGYTCNGGNGAYGGN---TCNGTNTCNATHACNAGYCCNGGNGAYATHTAY AARYTNTTYTCNCCNAARTCNATHYTNAARAARTCNAAYTGYTCNAGYYTNGGNYTNMGN TCNATHCCNCARAAYYTNCCNACNACNYTNGARAARYTNAAYYTNTCNAAYAAYAARYTN GGNCAYYTNGTNACNTGYTCNTTYGCNMGNTAYCCNAAYYTNACNGARYTNTAYYTNGAY AARAAYAAYATHGGNTCNATHGGNAARGAYTCNTTYGTNGGNATGAGYAAYYTNAARTAY YTNAGYYTNACNAARAAYCAYYTNACNYTNTCNGAYATHTGGTAYCCNMGNGGNTGYTTY AARCCNYTNMGNTCNYTNGARATHYTNGAYATHMGNATGAAYGAYCCNAAYAARAAYAAY GCNTCNGTN---TAYCCNGAYCARACNYTNGGNGAYYTNCAYAAYYTNMGNGARYTNTAY ATGGAYGGNYTNACNAARCCNGTNTTYGGNAGYGGNTTYGCNAAYATGACNTCNYTNAAR AGYYTNGGNGTNGCNGGNTTYTAYCAYGGNTAYTGYAAYATGGARGGNYTNTCNAAYGAR ACNTTYAARTAYYTNTTYMGNYTNGARACNYTNAAYYTNAGYAAYTGYAARYTNATHGGN GARGARATGGCNYTNAAYGCNTTYGGNYTNYTNGAYAAYYTNAAYATHYTNGAYYTNACN TAYAAYTAYAARATHGGNYTNGAYCAYTTYAGYMGNATHYTNTGGCCNYTNACNGAYAGY CCNAARYTNGARGARYTNMGNGTNCCNGCNATHCARGAYMGNTAYAGYCCNTGGAARACN TTYACNAARGARATGGCNAARAGYYTNCCNMGNMGNYTNAARACNYTNGTNGCNTGGGGN AAYMGNATHGAYTCNATHGARCCNGGNGTNGTNTCNGARYTNCCNGARAAYYTNACNACN YTNAAYYTNGGNGAYAAYTCNYTNTAYTAYGGNCAYTAYYTNAARGAYTTYTGGAARATG ACNAAYYTNCARACNYTNGAYYTN------------ACNTCNAAYTAYATHGTNTAYTTY ATHCCNAARTGGAARTGGCCN---------TCNMGNMGNAARMGNGAYYTN---ACNAAR MGNYTNGAYGAYATHGTNTCNGGNTCNGARAAYTTYAARYTNCCNCCNAAYYTNCAYGTN ATHMGNATGGTNAAYACNGAYGTNCAYGTNTAYYTNACNGARTTYTAYATHGCNCCNAAY AAYTCNYTNGARGTNYTNGARYTNGAYGARAAYGTNTTYCCNATHGTNGARGGNCCNTTY CAYAAYTTYAAYGCNYTNAARAARYTNTCNATGAARAAYTGYAARATGAARGARATHTGG CARACNTTYYTNAARTCNTTYCCNAAYYTNGARTAYYTNGAYYTNACNAAYAAYTGGYTN GGNAAYMGN---------GGNATHGAYTAYTAYCCNTTYGARGGNATHGARMGNYTNMGN GTNYTNAARYTNGCNTTYAAYAAYATHAARCAYYTNCCNAARAAYGTNTTYGAYGGNYTN ATHGGNYTNGARYTNYTNGAYYTNACNGGNAAYYTNATGTGGCARYTNGAYGCNGAYYTN TCNAGYYTNAAYMGNYTNCARATHYTNGAYATGAARCARACNTCNYTNMGNAAYYTNCCN GAYACNMGNAAYCARATHGAYAGYYTNCCNGGNATHAGYGTNAAYATGAGYGARACNCCN ATHCCNTGYAAYTGYGGNAAYYTNGAYTTYATHAARTGGYTNTCNCAYTCNTAYGCNTTY CCNGTNCAYATHTAYCAYTAYAARTGYGTNTAYGAYMGNAARGAYATHCARGAYAARTAY AAYGARACNATHATGAAYYTNGARMGNGCNTGYAARTCNGAYATGATGGTNYTNYTNTCN TGYYTNATHGTNATHTCNATHGTNYTNATHAGYACNYTNGGNTTYACNATHTAYMGNTTY MGNTGGMGNATHAGYTAYATGTTYGGNATGAGYAAYTAYATHYTNTAYGCNATGGTNCAR AAYYTNGCNYTNGCNGCNGCNGGNTGYGTNYTNCCNTCNATHTTYGGNGCNGTNTAYTTY ATGGCNTTYYTNATHACNYTNACNYTNTGGGGNTTYTAYAARACNGGNGGNATHGCNCAY GGNTGGTGGMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GCNTCNGGNTTYACNYTNYTNGCNGTNGCNATHGAYMGNTAYAGYMGNATHTGY MGNCCNYTNMGNGARCARYTNACNGCNAARMGNGCNTGGAARMGNGTNATHATHGCNATH GTNCCNTCNYTNGTNTTYGCNGGNCCNTCNTAYYTNGTNTAYGGNYTNAARCARGTNGAR GGNGTNTAYGGNMGNGARTGYTCNACNAAYCAYGARTAYYTNGAYCAYACNYTNCCNATH ATHTAYAAYTCNATHYTNTGYGGNGTNTTYYTNACNACNTTYYTNGTNYTNATHGCNTTY TAYGTNATGATHGGNMGNAARGTNYTNGGNCARYTNMGNTTYGAYCARGARGARGAYTGY TCNTGGTCNGCNGAYACNAARCCNTCNGTNAGYMGNACNYTNGAYCAYGAYGGNTGYGCN GCNATGCARATHCARAAYGGNGAYATHAAYMGNMGNCCNTCNGTNTTYCARMGNAGYAAR TGGTCNCARGGNGCNGARTCNAAYACNMGNAARACNACNYTNATGYTNTTYYTNATHACN YTNGTNTTYGTNATHAGYTTYYTNCCNCAYYTNATHATHAARGGNATHCARGCNATGGAY TCNCAYTTYAAYGAYTCNGTNGGNGAYGCNCAYYTNATHYTNTAYAAYATHTTYGTNMGN TCNTAYTTYTTYAAYACNGTNGCNAAYTCNTTYATHTAYGGNTTYTGYAGYCCNAARTTY AARAARGARTGYAAR---------GAYGTNGTNATHGGNTTYCAYGARAAYGAYTTYGAY TTYGCNAARAARYTNGCNGARAARYTNAARMGNTCNGGNYTNACNGTNTGGCAYTCNMGN CCNAAYGGNGAYGTNAARGARACNAGYGARGCNATHYTNGGNTGYAARGTNTTYATHCCN ATHATGACNGARCARTCNGCNATHGAYAARAAYYTNAAYGAYCARYTNTCNYTNGCNTAY ATHTCNAAYTCNGCNACNTAYCCNYTNGCNAARGTNMGNTTYMGNTTYATHAGYGCNAAR YTNAAYGGNGGNACNMGNYTNATHYTNGCNAARATHAAYTGGTGYTTYGTNATGAAYGAY GAYGARTTYGARCARAARACNGAYGCNYTNATHGARAGYGTNAARGCNGAYATHGCNAAY ATH---AARATGGARGTNGARTCNYTNACNAGYGGNGGNTTYATHCAYACNCAYGGN--- ---ACNAARGTNCARYTNGGNCAYGGNGTNGAYYTNGGNGGNGAYGGNTCNGGNTTYGAR GGNGCNATGGARMGNATHTAYYTNTCN------GAYAARGAYACNCCNTTYTGGGARMGN CAYTTYAARGGNAARAAYGARGTNACNTGGGTNGARTTYMGNGAYAAYTTYATGAARGAY TAYGGNYTNAARATHACNGARGAYTTYGCN---AAYAARGARGARMGNAARAARTAYTTY GTNAAYYTNATGTAYAARGAYGTNTTYTAYYTNAAYAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHGAR CARYTNGARAARGARATHGARAARTAYGARGGNMGNYTNGARGARATHGARMGNATGAAY MGNYTNACNGAYATGAGYGAYGARAAYTGGGARACNYTNAAYAARGARAARYTNAAYYTN GARAARCARYTNACNGGNGGNMGNAARAARATGMGNAGYYTNMGNTGGGARAAYTGYMGN AGYATGYTNATHTCNGTNGCNYTNYTNGCNATHATHTAY--------------------- ---------------------------------------------GTNCCNAGYATHGGN CARATGAGYTAYCCNTTYGARCCNACNAAYTCNYTNTCN---ATHTAYGAYCARGARAAR TTYGAYAAYAAYATHAGYTGYGGNGCNAGY------------TCNATGTCNAARGTNGAY AARTGGGAYACNGAYGARYTNTGYGAYYTNGAYGAYAARATHGARAAYAGYTCNYTNCAR AGYYTNYTNACNCCNGARATHATGAGYAAYYTNTGYGCNCCNTCNACNACNTGYTCNCAR GCNTTYCCNTGGAAYGARAARCCN---ACNYTNGAYTCN------ACNTCNGTNGGNTCN GCNGAYGTNAAYATHACNYTNAAYCARYTNAAYATGGAR---------TCNTTYATHGAY GAYATHYTNAAYTGYGAYACNAAYGAYAGYAARTTYTCNGGNATHGARTTYATGTGYAAY GAYAGYMGNAAYACN------------------------------TCNAGYMGNAAYACN CCNACNTGYGGNACNCCNAAYCCNATHAAYAAYGAYCAR------------------ATH AARTCNGCNCCNGGNYTNYTNAARAAYTCNTCNACNGARACNGTNGGNATHGAYTTYYTN AARAAYYTNYTNCCNATGAAR---CAYTTYCCNCCNMGNGARAAYTTYCCNACNATHGGN GTNGTNCCNCCNGTNAARCARCARAAYAAYATHGTNACNYTN---ATGGCNATHTTYCCN GARCCNACNAARCCNACNGGNGCNCCNGTNYTNCAYGAYYTNYTNAGYAARTCNTCNAAY GGNAAYGGNAARGARGTNCARGARYTNAARTGYGGNTCNTCNAGYGARGCNAAR------ YTNAARTCNGARYTNCARTCNCARATHGTN---CCNTCNTCNGGNGCNATGATGAARAGY TGGGAYYTNGARATHAARTCNGARCCNAAYTCNCCNGAR---TCNATGATGAARCAYTAY TCNGARGARTTYGGNGCNTCNAAR------------------------------------ ------------YTNAARMGNAARMGNTGYGAYTCNGGNGGNTCNGGNGAYGCNTCNGAY GAY---GAYGARGARGAYGAYACNAAYTCNCCNCAYGAYAGYTCNGAYAGYGARGAYGAY GAY---TCNGAYATHGAYGCNGAYGTNMGNAAYATGTCNACNATGGGNCAYGARTCNYTN ATHGCNATHGGNAARAARCARAARCARTAYTTYTGGCARTAYAAYYTNCARGCNAARGGN CCNAARGGNACNMGNYTNAARYTNAGYGTNGARTCNCCNTCNGAYCCNCAYGTNYTNAAY TCNATHGARGAYCCNGTNTTYGAYGARAGYAGYACNACNGTNGCNGGNATHMGNCAYGGN GGNAARGCNMGNAARGGNGAYGGNAAYGARGTNGCNCCNAAYCCNTAYAARYTNTGYAAR ATHGGNCARCARYTNATGAARYTNAAYGARAARATHAAYATGTGYCARYTNGGNACNGAY GTNCCNGCNGCNAARMGNAAYGARGCNMGNAARGARAARAAYAARYTNGCNTCNMGNGCN TGYMGNYTNAARAARAARGCNCARCAYGARGCNAAYAARATHAARYTNTAYGGNYTNGAR GAYCARCAYAARCARYTNAAYAARACNYTNGGNYTNATH------------------MGN CCNAARATHTTY------CARATGGCNAARGAYATHCARTCNACNGGNAAYACNATGACN ACNTCNYTNACNGAYYTNATGAAYACNTAYATHMGNGAYTAYTTYATHACNGAYGTNGCN GGNAAYACNACNGAYTAYGTNAAYAGYGTNATHYTNAARGTNGARGCNGGNGAYAAYGCN GGNGGNYTNGGNATHAARMGN---MGNAARACNGGNMGNAARTCNAGYCCNCARAARAAR GTNCARGTNCAYCAYTCNACNCCNMGNMGNAGYGCNMGNAARTCNACNGTNGTNGGNGTN AGYGGNGARGGNACNGCNATHGGNAGYAAYATGGARYTNGCNATHGCNTAYAAYATHGAR MGNCCNCCNYTNTCNCARAARGCNTCNMGNGCNYTNCARGARYTNATHGTNGARAARGTN GAYGGNGARTGYAGYTTYGTNGARGTNCCNYTNGAYGAYACNYTNAAYCARAGYGAYTCN GGNGAYAARATGTCNGCNAAYAGYAGYGAYGCNGGNAGYGGNCARTCNACNYTNTCNTTY ACNCCNCAYMGNTCNCAYGARYTNATHAGYTCNGARTCNTCNYTNGAYAGY--------- ---ATHAARACNCCNAARTCN------ACNAARAGYMGNTCNYTNGCNCCNTCN---TCN GGNTTYAARGARCCNGGNCAYCCNYTNTCNGCNGCNMGNAGYGCNTCN---MGNMGNMGN MGNACNGARACN---------TCNMGNAGYGAYGARGARATGGTNGAYTTYYTNAARAAR AGYCCNATGGTNGARATGACNMGNMGNAARTCNMGNCAYGTNTCNTCNCCNGCNGAR--- ------GTNAARTAYTTYMGNGAYYTNATHTCNTCNGARACNGAYCARYTNAAYACNYTN TGYMGNGARTGGAAYGAYACNGCNGCNTTYACNCARGGNYTNCAYGAYGAYATHYTNGGN CARATHMGNTGYGCNGTNGGNAARGCNCARYTNYTNATHTCNCARMGNTTYAARCARTTY TCNGGNYTNATHGAYAAYTGYGARTTYAARYTNGGNGARAARGARACNACNCCNACNGAY YTNCARGGNTTYTGGGARATGATHTAYTTYCARGTNGARGAYGTNGARAARYTNTTYGCN ACNYTNACNACNYTNAARYTNAAYGAYTGGCAYAAYGAYCCNGGNACNCCN--------- ---------AARAARGARATHGTNACNAARAARAARACNGTNGCNAARGGNCCNAARMGN AARGTNGARTCNAARTTYGCNGCNTTYMGNGCNGARYTNATHAARMGNAAR--------- ------------------GARAAYYTNAARAARATGAARGTNYTNGARYTNAARCARGCN YTNAARGAYMGNGGNYTNGTNACNGCNGGNACNAARCCNGAYYTNATHAARMGNYTNGCN GARGCNATGGGNACNTCNGTNGARAGYTCN---GAYATHTCNYTNGGNGARGGNYTNGAY GCNATHGAYGARATHYTNAAYGAYGAYCCNGTNCCNCCNGCNGGNTCNAARTCNCCNGTN GCNACNTCNGCNTCNGCNGAYTCNTCNTCNGTNGTNACNGAYCCNACNTCNACNACNACN AGYGGNGARGCNGCNTCNAAYAAYGGNYTNTCNCARAARAAYGAYGGNGCNGAYGAR--- ------ACNGCNGARAGYTCNGAYCAYAARGCNAARCCNGARATHGTNMGNAGYYTNAGY GARGCNGARMGNYTNAARYTNMGNGCNCARAARTTYGGNGTNACNTCNGARGGNGCNAAR AARGARATGMGNGCNCARMGNTTYGCNATHACNGAYGGNGGNGAYGCNAARACNGGNGTN ACNGCNAGYGAYAGYACNCARGAYYTNGARAARYTNAARAARMGNGCNGARMGNTTYGGN GCNGTNACNTCNACNTCNYTNTCNAARYTNTCNGARGAYGARAARAARMGNAARMGNGCN GARMGNTTYGGNACNGCNGCNYTNACNCCNACN---------GCNGTNAARACNTCNATH TCNGAYAGYGARYTNGARGCNAARAARMGNAARMGNGCNGARMGNTTYGGNYTNGCNAGY GTNTCNTGYCARTGGMGNGGNTGYACNYTNGAYCCNAGYGAYYTNYTNGAYCAYGTNMGN AARCAYGCNGARGARCARATHTCNAARGARAARTAYGCNTGYYTNTGGGARGGNTGYAAR GTNTTYGAYAARCCNTCNTGGTCNMGNTCNTGGYTNGARMGNCAYGTNATHTCNCAYGGN GGNCARMGNCCNTTYAARTGYATHYTNCCNGGNTGYGGNCARMGNTTYCCNTCNCARGCN GCNYTNGARMGNCAYGTNAAYGGNCAYTTYGARGCNCARGCNAAYGGNAGYGTNGCNAAY GGNAAR------ACNYTNAARACNAAYCAYGCNATGGTNTTYATGGAYTCNCARATHGCN GARGTNYTNCAYTGGAGYGGNGGNATHAAYYTNYTNYTNAGYGGNGGNGCNCARGAYATH MGNAAYTTYTCNTCNTTYGARAGYGGNAARGARTCNCARAARAARGCNGTNTTYATHGTN AGYTCNCCNATHGARGGNGTNACNMGNCARGTNGTNAARGAYATHGTNACNCARAGYCAY TTYCARTAYGTNGTNATHTTYACNACNTCNTGYACNTTYYTNCAYGCNGAYACNYTNCCN GGNGAYCCNGARACNGGNGARATHTTYGARGAYYTNCARGARGARATHYTNCARTGGATG GGNAAYATGAAYTAYACNGCNGARGTNTTYCAYGCNAARATGTTYGGNTGYCARYTNAGY CCNAGYATHTTYATHACNCCNGCNTTYTCNTCNATGTTYCCNYTNYTNGTNTCNGAYYTN MGNCARGTNAGYTAYCARCAYAAYAARTCNATHAGYGGNAARGARTCNGTNTCNTTYGAY AGYATGAGYGAYGTNGARTTYTCNCAYATGCCNAARGCNYTNCARACNCARATHMGNYTN YTNGCNGTNGGNTTYCAYAGYYTNTTYCARCARTAYACNYTNAARGARGAYATHTAYTCN ATGGGNCAYYTNAGYMGNYTNGTNGCNTCNGARYTNGAYAGYTAYCCNCCNGCNAARTCN MGNMGNAARACNTCNCARAARMGNGCNTCNYTNYTNYTNGTNGAYMGNACNYTNGAYYTN GCNTCNGCNGTNAGYCAYCARATGGAYYTNYTNATGGAYMGNGTNGCNAAYACNYTNCCN AAYYTNCCNGGNCAYACNAAYGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGYTNGARCAR GCNYTNAARACNACNGAYTGGATHAARATGGAYACNTGGGARAGYGARCARAARACNTGG YTNGARACNGCNAARATHYTNMGNCAYTTYAARACNCAYGTNGARAGYCARTAY------ GGNCAYAARCCNTCNCCNTCNAARMGNMGNAARAARCARACNGTNTCNGAYYTNCCNCAR AAYCARGTNCCNAARATHGARATHGAYGGNGAYCARACNCCNCAYGTNAARYTNYTNTGY GGNGCNGAYYTNYTNGARTCNTTYGCNGTNCCNGGNYTNTGGGCNGAYGARGAYATHGAR TAYATHGTNGGNACNCAYGGNYTNGTNGTNATHACNMGNGCNGGNTCNGAYCCNYTNAAR TTYATHTAYGARTCNGAYGTNYTNACNAARCAYCARGAYAAYATHTTYATHGTNACNGAR TGGATHTAYAAYGAYATHAGYTCNACNAARGTNMGNMGNGCNYTNMGNMGNGGNGAYAGY GTNAARTAYATHGTNCARGAYAAYGTNATHTCNTAYATHMGNGARCAYCARYTNTAYGGN ATGCCNGAY------------------------------------------TTYAARATG YTNTGGYTNATGGGNMGNYTNYTNACNTTYTCNTGYYTNTGGTGYYTNCAYACNACNGGN ACNTGYATHACNAARYTNTGYCARYTNGCNCAYACNTCNGTNTTYAARGARMGNYTNGCN TAYCARGGNGGNYTNATHYTNTGYGARGCNGTNGTNGAYGARGGNACNGARGAYGAYATH CCNAGYGTNGARGAYGTNGTNGCNATGGTNATGGTNTCNCARAAYMGNCCNYTNGTNTCN YTNCARGTNGCNTGYCAYAARTGGGCNTGGYTNGAYACNYTNACNCARTGYAARATGYTN ATHGARMGNGGNCARCAYYTNCCNGCNATGAGYAARYTNCARGCNMGNYTNGCNACNYTN YTNGGNCCNGARGARMGNGCNAARYTNYTNTGYYTNTTYGGNGAYTGYTAYATHCAYCAR GGNTAYYTNCARYTNGCNAGYGARGCNTAYAGYAAYGCNTAYMGNTCNGAYTGYMGNTGY TTYAAYGCNGTNTAYMGNYTNTCNTGYGTNTAYTGYTGYCARGGNAARGCNTCNYTNGAR TTYGARATGACNAAYYTNYTNGTNAARATHYTNCAYCAYMGNGARAGYCCNTCNTTYGAY ACN---------------GAYYTNGAYGCNYTNYTNGARTCNGTNTGYCCNGTNYTNCCN GARATGACNYTNGTNAARGCNAARAARMGNYTNGCNAARYTNTGYYTNCARGCNGGNMGN TAYTCNAARGCNGCNCAYCAYTAYATGGARATHYTNAARATHYTNCARGARGARGCN--- ------GTNGCNCCNCARGARCCNTCNCARTCNCAYYTNGAYATHGGNGARYTNGTNGCN GARGCNGCNGAYGCNYTNGTNATGAAYGGNCARYTNGARGARTGYATHGCNYTNTGYGAY GARGCNAGYCCNATHYTNYTNTGYAAYGAY---MGNTTYTCNGGNAARGGNMGNCAYGGN ACNTGYGGNGAYGARYTNAGYATHGARGAYYTNCAYYTNAGYCARAAYCARTCN---CAR YTNAGYYTNTTYAGYAAYGCNAGYYTNGARGGNGARGGN------MGNATGGARACNACN GCNTTYTTYAGYACNTCNAGYGGNAGYMGN------AGYCARAARGARGARTTYGAYCAR ACNGCNGARTTYACNCCN---------------YTNTGYGCNAAYGCNGTNTCNAAYTTY YTNTCNAAYMGNAGYCARTAYAARGGNGGNGTNGGNGGNGTNTGYAARGARGARGARGAR GARMGNGARGTNGCNCARYTNTAYGCNGTNAARYTNYTNYTNAGYAARGCNGAYGCNATG GTNTCNGGNGGNAARGAYTCNGAYTGYACNGTNGGNTGYYTNYTNCARGCNCARAARATH YTNYTNGAYATGAGYTTYATGYTNAGYYTNGARAARGARTCNMGNTCNGAYTCNTCNAGY TCNTCNCCNAARACNAARMGNMGNTGYYTNAAYTCNTCNGAYCAYGAYGCNACNGTNAAY ACNGGNGAYTCNAGYTGYCCNCCNTCN---TGGCAYCARYTNGTNATHGAYGCNAGYYTN MGNYTNGGNYTNGCNTCNYTNAAYMGNGGNAARYTNTCNTCNGTNYTNAAYAGYTGYMGN YTNGTNYTNCARTTYGAYCCNGGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TCNYTNYTNMGNMGNYTNGAYTGG MGNGGNCAYCARGCNTTYGCNACNAGYYTNGARAGYCARGARTCNGTNCARGTNCAYGCN CARGCNGTNGARAAYAGYGGNAARYTNCARGARYTNGAYGTNAARGTNYTNATGGARGTN GAYGCNMGNGAYYTNCAYAAYCAYACNGAYYTNAAYACNYTNTGYTAYGCNMGNATHATH TTYAAYTTYCCNYTNGCNGAYMGNCAYAAYATHAARAARAAYMGNTCNYTNYTNGAYGAR TTYYTNGCNAGYTGYAARCAYATHYTNACNAARACNGGNCARGTNATGATHACNYTNTGY AARGGNCARGGNGGNACNCCNGCNGAYCARCCNATGMGNTCNTGGCARGAYAGYTGGCAR GTNGTNGCNATGGCNGCNAARTCNGGNTAYGTNYTNACNGAYGTNGTNCCNTTYTGYGCN ACNGARTTYCCNGARTAYCAYAGYGTNGGNTTYMGNTTYCARGAYAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AGYATHMGNATHACNTAY CARACNGARCCNCARTCNACNGCNYTNGCNTGGYTNCCNGCNGARCARACNGAYAGYGGN AARCAYCCNTAYYTNTTYTCNCARTGYCARGCNATHCAYGCNMGNTCNYTNTTYCCNTGY CARGAYACNCCNGGNGTNMGNGCNACNTAYGAYGCNAARGTNACNGTNCCNAARGARYTN MGNGCNYTNATGTCNGCN---YTNYTNGAYACNACNGARGTNGTNGGN------GAYTCN TGYGTNACNCCNTTYAARCARCCNGTNGCNATHTCNTCNTAYYTNGTNGCNYTNGTNGTN GGNAAYYTNGARAARMGNGAYATHAGYGAYMGNGTNGCNATHTGGTCNGARCCNCARGTN GTNGARGCNGCNGCNTTYGAYTTYAGYGAYACNGAYAARTTYGTNAGYGCNGGNGARGCN YTNGTNGGNCCNTAYGARTGGACNMGNTAYGAYGTNGTNTGYYTNCCNGGNTCNTTYCCN TAYGGNGGNATGGARAAYCCNTGYYTNACNTTYGTNACNCCNTCNYTNYTNACNGGNGAY AARGCNYTNTGYGAYGTNATHTGYCAYGARGTNGCNCAYAGYTGGACNGGNAAYYTNGTN GGNCCNAARACNTGGGARGAYTTYTAYYTNAAYGARGGNTTYACNATGTTYYTNCARMGN AARATHATGTCNMGNYTNTAYGGNGARGARTAYTTY---GAYTTYGAYGCNATHCARGGN TGGGAYGAYYTNAARAAYTAYATG------GARYTNGTNGGNAARGAYCAYGCNTAYACN GTNYTNMGNCCNAAYYTNGARGGNGTNGAYCCNGAYGAYGCNTTYTCNGTNGTNCCNTAY GARAARGGNTTYAAYTTYATHTGYCAYYTNGARTCNGTNGTNGGNAAYAARAARTGGTTY GARCARTGGYTNCAYGARTAYATHCARACNTTYAARCAYCARGCNATHACNACNAAYGAY ATGGTNAAYCAYYTNGTNCARTTYTTYAGYCAYGARGAYCAYAARGCNGAYTTYTCNAAR GTNGAYTTYGTNGCNTGGYTNGAYACNCCNGGNATGCCNCAYGCNATHCCNGGNTTYAGY TCNAARYTNYTNGAYGAYGCNGTNGAYYTNGCNCARMGNTGGAARAGYGTNGCNGARGGN ACNGCNAARGARGTNTCNGARAAYGAYATHAARGGNTGGTCNAGYTCNCARATHTGYTGY TTYYTNACNMGNGTNGAYTTYCCNATGCCNGTNGAYTCNYTNACN---------YTNATG GAYACNCAYTAYAARTTYAAYAGYTCNAARAAYTGYGARGTNYTNTTYYTNTGGYTNAAR YTNTGYATHMGNAAYAAYTGGACNTCNCAYGARCCNGTNYTNMGNTCNATGYTNGCNMGN ATHGGNMGNATGAARTAYACNMGNCCNYTNTAYMGNGARYTN---------AGYAARGTN GAYCAYAARGCNGTNGCNATHTTYAARGARAAYAARCARAAYTAYCAYAGYATHTGYCAR AARATGGTNGGNAARATGTCNGTNGAYATHMGNAGYAGYGARMGNMGNMGNTAYCARGCN MGNGAYTCNMGNGARAARGARATHGCNGCNYTNAARGTNTCNCARCCNGARTCNCCNAAR GGNGTNCARGARACNGAYAARMGNATGMGNMGNGARATHGCNAAYAGYAAYGARMGNMGN MGNATGCARTGYATHAAYGCNGGNTTYTCNTCNYTNMGNTCNYTNATHCCNCARYTNGAR GGNGARAARYTNAGYAARGCNGCNATHYTNCARCAYACNACNGARTAYATHGCNGGNYTN GTNAARGAYAARGCNMGNYTNCARATGCARYTNGAYCAYYTNAAYMGNGTNYTNTCNGAR ATGGGN---CARGARMGNGTNGTNAARGAYAGYTAYATGGCNAAYTCNCCNCCNCCNTCN AARMGNAARAARMGNGARACNGARTCNTCNGAYGARGGNGTNGGNTCNYTNTCNGAYGCN TCNGAYGARGGNACNTCNGARYTNMGNCARGARATHGAYTCNYTNMGNTCNGARYTNGCN CAYGARMGNCARMGNTCNTCNGARYTNCAYGARMGNAAYYTNTTYYTNGARTCNCAYGTN YTNCAYYTNCCNGTNAARGGNGCNATGGAYYTNCCNCARACNCARTAYTCNGARYTNACN CARCARGARCCNGTNTAYCAYCCNGARGTNGTNGARGTNGTNGCNGCNMGNGARGARCAY AGYCCNGTNCCNCARCCNMGNCCNYTNGTNATGGARCAYMGNAAYCCNGTNGARGTNGCN GTNCCNGCNTGYACNGTNGAYTCNTCNGCNGTNAARATGGARATGCARCARYTNGARGCN CAYACNCCNGTNACNATGGTNGCNCCNACNAAYACNAAYACNAGYMGNGGNGCNYTNGAR CAYACNTAYTGYCAYMGNGAYCAYCCNMGNMGNMGNCAYCAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GAYYTNAARCARGGN YTNACNTCNGARAGYATHCCNACNTGYCCNAAYGTNGARAAYGTNMGNTTYGAYGTNATG CAYAGYMGNATHATHGARGCNYTNCAYAARTTYAAYGGNGCNCCNTTYACNATHCARMGN YTNTGYGARYTNYTNACNGAYCCNAARAARCAYTAYAARMGNAGYGAYAARTTYYTNMGN GGNYTNGARAARAAYGTNYTNGTNGTNAGYACNGTNGAYCCNTAYGGNMGNAARGTNGTN TCNGARTCNTCNAGYAARTCNYTNGTNAAYGGN---ATG---GAYATGAAYGGNGCN--- TTYCCNCCNMGNGAYTCNGCNCAYACNGTNCCNYTNCCNCCNGTNCCNGGNTGGGTNACN AGYATHACNGCNGCNCCNAGYMGNGTNCARTCNGTNTCNTCNYTNAAYACNTCNCCNGAR CARYTNTTYAGYCAYCARACNTCNYTNGAYGGNAGYGGNGCNGTNGCNAAYGGNGTNTCN AGYAGYYTNGTN------AGYTCNGTNTAYTCNGARCARGGNGAR---CCNYTNGCNGTN CARTCNGTNGARGTNGTNGARGARACNGTNGTNACNATGGARACNAAYGAYGTNAAYCCN GTNGCNACNGAYGGNGGNGARGGNATGGCNGARGAYGARGARGARGGN---------ATG GGNGARGAYMGNGAYACNTCNTCNTCNTCNTCNGARGARATGTCNGCNTCN--------- TCNGAYACNGGNGARGTNAGYATGMGNGTNCCNTCNTTYGGNGTNTCNGTNACNTCNTCN TCNGARACNTCNGGNGAYAGYTCNGCNTGGGTNGCNATGGCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNAAYTGYATGGTNYTNAGYYTNTAYCCNGGNTCNGARGGNTAY TCNATHATGYTNMGNTCNMGNAGYGGNGTNGARTCNGARACNATGAARYTNCCNTAYGAR GARTCNGARATGYTNGARTAYGTNGAYTCNGGNCARYTNCCNCCNTTYYTNYTNGAYYTN YTNGARAARGCNCARATGAAYATHTTYTAYAGYGGNTGYGTNGTNGTNGARGTNMGNGAY TAYMGNMGNTCNGCNACNGGNACNCAYGAYTCNAARTTYGTNYTNYTNMGNCCNTGYCCN CARTCNATHYTNMGNGAYGTNGCNGCNATHAGYTGYGAYGGNCAYACNTGGAGYCARGAY GAYYTNGTNCAYYTNGARAGYGARYTNATHYTNGCNACNGARGARCCNYTNTGYYTNGAY CCNTCNCCNGCNGTNATGYTNGTNGARAAYGCNYTNCARTAYGARGCNAARTGYYTNAAY AAYCCNGCNATHAARMGNTCNGTNAARAAYTAYACNGARGTNGCNYTNAGYMGNAARMGN AARYTNGCNCARGCNCCNGCNCCNGAYGGNATGMGNYTNCAYGAYTTYGTNACNAARAAR MGNGARAARGCN------ACNAARGCNMGNMGNTCNATHGAYAAYTTYATGGARCCNGCN ACNCCNAAYYTNTCNAARCCNAGYACNATHGARGTNAARAARTTYATGAARYTNCCNAAR AGYCCNGCNCCNAGYGGNATGATHTTYGTNGARGARCAYATHYTNGARMGNGAYCCNACN CAYAAYTTYCAYATGATGGCNAARATHACNACNTAYCARCCNCARTTYGGNGAYAGYTTY TAYGGNGARTTYTGYYTNGAYCAYAARTAYTTYCARGCNAARTCNYTNGAYGAYGTNMGN MGNTGYMGNTTYGARYTNGGNACNMGNCARAARGTNGAYMGNTAYYTNAARCARTTYAAR GAYATGTTYACNGARCAYGGNAAYGTNCARGTNAARATHTCNATHMGNCARGCNAAYGAR TCNGTNCCNGCNGTNACNTAYACNCARGGNATHCCNGCNACNCARACNGCNCCNACNACN GCNTCNGCNCARAARACNYTNGCNAGYAGYYTN---GCNCARGCNCARGGNAARACNATG ACNYTNCCNAARGTNAGYGCNAARTCNGGNGGNATHGTNGCNAGYYTNGCNGCNAARMGN AAYATHCCNATHCARYTNACNATGTCNATHAAYGCNGCNAAYGCNGCNTCNGCNGGNATH CCNACNACNYTNTCNCCNCARTTYATHACNTCNCCNYTNCCNACNGCNGCNYTNGCNGCN CARMGNYTNAARGCNGCNGGNGTNTCNCARYTNMGNTCNAGYTCNTCNCCNACNGTNTCN TCNTCNATHACN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYGAYGTNTAYGCNGGNGTNGAYGTNTTYGGNMGNTCNATH GGNTGY---AARGGNTTYGARTGYCAYAARGCNATHCARATGATHAARGARTGYGGNYTN TCNTAYGCNYTNTTYGCNCCNGGNTGGGTNCAYGARTGYYTNGGNGCNGARAAYTTYGAR GCNAAYGARGCNAARTTYTGGGGNYTNYTNTCNGGNYTNGTNCAYTCNMGNCCNGTNTCN ATGCCNYTNGCNACNTCNTTYTGYCARGGNTGYGGNCARAARYTNTTYYTNGARGGNCAR GTNGCNAGYGAYAARCCNTGGTTYAAYYTNAGYATGCARCARGTNCARCCNTCNTAYACN TGYAGYTCNYTNAGYCCNAGYCCN---MGNCCNATGTCNGAYAARGARGARTCNCCNGGN YTNTCNCARGGNYTNGARAARCCNGGNTCNTCNCCNAARTCNAAYCARGAYAGYACNCCN GARAARATHGARGCN------------CCNYTNGARAARGARAARTCNTCNCARGCNGCN GGNAGYAARCARGAYGTNCCNTCNACNTCNTCNTCNTCNACNCCNGCNACNGCNGCNGCN TCNTCNTCNTCNCARCCNTCNACNTCNACNGCNACNAGYCARGAYMGNAARMGNAARGTN GARATHTCNGARGARGARATGAARCARTAYATHAARAARCAYCARAARCARGARGARGAR MGNATGAARATGCARGTNYTNGTNTCNAAYTTYTCNGARGARCARYTNAAYMGNTAYGAR ATGTAYMGNMGNGCNACNTTYCCNAARGCNGCNATHAARMGNYTNATGCARAAYATHACN GGNACNTCNGTNTCNCARAAYGTNGTNATHGCNATGTCNGGNATHTCNAARGTNTTYGTN GGNGARGTNATGGARACNGCNYTNGAYGTNYTNGARAARTGGGGNGARTCNGARCCNYTN CARCCNAARCAYYTNMGNGARGCNGTNMGNATHYTNAARACNAARAAYCARATHCCNACN ACNAARAGYAARAARACNYTNTTY------------------------------------ ---------------GGNAGYTGYCCNGGNGTNYTNGCNGGNGAYCCNAARACNGCNAGY TGGGGNYTNATHGTNYTNCARGARTGGTGGGGNATGAAYCARCARATHCARGAYAARGGN AARGARYTNAGY---GAYCARGGNAGYATGGTNACNYTNGTNCCNGAYYTNTAYMGNGGN AARTGYACNAAYGAYCARGARGARGCNGGNCAYYTNATGGGNGGNYTNGAYTGGAARGGN GCNGTNGAYGAYATHCARGGNTGYGCNGARTAYYTNAARAARCARGGNGTNAARAARGTN GGNGTNACNGGNTTYTGYATGGGNGGNGCNYTNGCNATGGCNGCNGCNGCNYTNGTNCCN GARGTNGAYGCNGCNGTNCCNTTYTAYGGNATHCCNTCNGCNGARYTNTGYGAYGTNACN AARATHACNGTNCCNYTNCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARAAYTTYATHYTNCARCCNGAYAGYCCNGAYACNGGNAARMGNMGNGGN GTNGGNGGNGCNGARACNCARGAYATHCCNCCNGTNGAYTTYGAYTGGAGYTCNAGYGGN YTNACNAAYCCNYTNTCN---TTYMGNCARAAYAGYTTYGARGCNAARYTNCCNTCNTTY MGNCCNYTNGARGAYATHYTNAARAARAGYAARCCNACNGCNAARYTNYTNAGYCCNGAR GCNGCNAGYATHATHCARAARATGCCNGAYATHAAYTTYATGCARTCNAARGTNYTNATG TTYCCNATHAAR---------------------------------------AGYACNGCN AGYGAYATHGGNAGYATHTGYCAYYTNGTNATHGARAGYTTYTGYAAYGAYTCNACNATH TCNTCNGAYAARGTNGCNGCNGCNTGGTCNYTNGARGARTGGTGGGAYGTNMGNGCNGGN YTNYTNGCNGTNGTNAARAARGCNGTNAARAARGAYTGGAGYAARGAYGARATHGTNGAR TGYYTNGGNTCNYTNGAYGARGCNTAYAARAARGTNATHACNGARGCNATHTCNGTNCAY MGNCAYTCNGTNCARTCNAARYTNATHCARGARACNGCNGCNGTNTCNCARTCNGTNYTN TCNGAYTTYGAYTGGAARGTNCARYTNGCNATGTCNAGYGAYAARYTNGCNTCNATHCAR CARCCNTTYYTNCARYTNGAYTTYGAYATHMGNCARTGYGAYGGNGAYAARGARACNGTN ACNYTNGARYTNGAYMGNGARGARYTNTCNAARTTYATHTCNTCNYTNGARGCNTGYAGY AARACNGGNGCNAGYGTNATHGAYGAYGTNYTNAARGARGTNYTNGARTAYGCNGTNMGN GAYTAYATHAARACNTGGTAYMGNCARATHAGYGAYCAYGAYAAYTTYYTNGTNGAYATH TGGAARTGYGCNCARAARGTNATHATHACNTTYTCNAAYMGNTCNAARGARGTNAAYTGG ACNCCNTAYTTYACNGARMGNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CARGGNGGNCAY---------CAYCAYGGNAARCCNYTNGARTTYGCNTCNGAR GTNCAYAAYMGNGARCAYGTNYTNGARCAYYTNCARMGNGTNGTNGCNACNAARAARAAR GARGARATGACNGARGARGARYTNGARTTYCAYTAYTTYAARYTNCAYGAYAGYGAYAAY AAYAAYAARYTNGAYGGNYTNGARATHAGYAARGCNYTNACNCAYTTYCAYGARGAYAAY ACNGGNACNACNGARGCNAARGTNTTYGGNGAYGAYGARATHTCNAAYATHGTNGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MGN ACNAAYYTNGARAGYGAYMGNGAYAGYGCNMGNAGYTCNCCNAGYGARTCNAARMGNGTN YTNAARGGNCCNTCNGTNGCNGAYCARGTNCCNGGNTTYCARTCN------YTNACNCCN GCNCARCARGCNGARGARMGNATGMGNYTNGCNYTNAARGCNGCNGCNACNGCNGAYGAR AARYTNMGNGARAGYGCNGCNAARTCNGAR---AAYGGNAAYTCNAGY---CCNGCNAGY YTNATGAAYACN------------------------CARGCNTTYGCNAARTCNYTNGCN TCNATHGARTCNGAYAGYTTYGTNGCNGGNACNTTYAARTCNTCNAAYTCNAARATHAAR GARGAR---CCNATHGAR------MGNGTNAGYCAYGAYAAYGCNATHTTYGGNTCNYTN TCNATGTCNGGNTTYACNYTNCARCCNGAYCCNGAYTCNMGNYTNACNAAYATHGAYGCN GAYTCNATHATHCAYCCNAGYYTNTTYTGYGAYCCNGARGAYAARATGGAYAARTGGATH GARMGNYTNACNYTNATGMGNAARMGNAARYTNGARGGNGAYGCN--------------- GTNGTNGGNGCNTGYTTYATGGAYTAYGTNTCNTAYGTNGAYMGNTTYCCNATGGCNGGN GARACNYTNCAYGTNAAYGAYTTYAARAARGGNTTYGGNGGNAARGGNGCNAAYCARGCN GTNATGATGGGNAARYTNGGNGGNMGNGTNMGNATGGTNGGNYTNGTNGGNACNGAYGGN GAYGGNGARGARTAYYTNAARAAYTTYGARMGNGARGGNATHGARACNAARTAYGTNACN AARGTNGARGGNGARTCNACNGGNYTNGCNAARATHYTNGTNGAYAARACNGGNGARAAY ACNATHGTNATHTGYCCNAAYGCNACNAARAARGTNTCNGTNGARCAYATGAAR---GGN YTNGAYTGGATGGARGGNACNGAYATGGTNGTNTGYCARAAYGARGTNCCNYTNGAYGCN AAYYTNTGGGCNYTNGARCARGCNTCNAARGCNGGNAARCARACNGTNTAYATHCCNGCN CCNGCNCCNACNGARCARYTNCCNAARYTNYTNCCNGTNATGCARTAYATHGCNCCNAAY CARCAYGARGCNTCNATHATGYTNGGNTAYACNGTNAAYGGNATHGARGARGGNAARAAR GCNGTNYTNGAYYTNMGNGARAARAAYGCNTCNTCNACNGTNATHATHACNATGGGNGGN GAYGGNTGYATHGTNYTNGARCCNAAYTGYACNACNGCNGTNCAYGTNCCN--------- ---------------------ATGTCNTTYCCNGGNMGNACNCCNATGGGNATGCCNGGN GGNATGCCNGGNATGGCNCCNMGNATGATG---ACNCARGGNTAYCCNTTYACNCCNATG GGNATGACNMGNATGACNGCNATGATGCCNATGCARATGGGNATGATGACNCCNATGATG CCNTCNATGATGGCNTCNCARCARATGCCN------CAR---ATGCARCARATGAARCAY AAYAARAARTTYGTNCCNCARGARATHCCNAARATGGAYTCNAARGARGAYAARCCNCCN GTNACNACNGTNTTYGTNGGNAAYATHAGYGARMGNGCNCCNGAYATGATGATHAARCAR ATGYTNCARMGNTGYGGNAAYGTNYTNAGYTGGAARMGNGTNCARGGNGCNTCNGGNAAR YTNCARGCNTTYGGNTTYTGYGARTAYGARGAYCCNGARGCNACNYTNMGNTGYATHMGN YTNYTNAAYGARTGGCARATHGCNGAYAARAARYTNGTNGTNAARGTNGAYGCNAARACN AARACNTTYYTNGAYGARTAYMGNAARAARAARCARGGNATHTCNGGNGCNTCNTCNAGY AAR---GGNACNGAYTCNAAYGGNGARAARAAR------------GAYGGNGARAAYGGN GAYGCNAARGARGARGAYAARAAYGTNGARGARCCNATHGAR---AARYTNGAYGARAAY ACNATGMGNGARGAYMGNGTNGCNAGYGCNGGNYTNGARGCNATHATGMGNGARTAYGCN TTYGARYTNGCNAARGARCCNATGAARTCNTCNGAR---TCNGGNGARGARAARGARAAR TCNGTNCCNAARAARGAYAARGAYYTNYTNYTNCARGCNAARAAYACNGGNTTYGAYGAY ATGGARATGGARGAYGARAARMGNGARATHATHAAYMGNGARATHAAYAARTTYMGNGAY MGNCAYAARGAYGAYGAYGARGARAARGARAARGAY---AARGARMGNGARMGNACNGCN CARMGNGARMGNGARMGNMGNCARGARGARAARMGNGTNMGNGARMGNATGGARMGNGAR MGNATGCARMGNGARMGNGARTCNTCN------------------MGNGAYMGNTCNAGY CARMGNGTNTCNMGNTCNAARTCNMGNTCNAAYTCNCCNGCNCCNTCNMGNTCNMGNMGN MGNTCNMGNTCN------------MGNGAYMGNACNAGYMGNGARMGNTCNMGNGARMGN MGNAARGARMGNGARGCNGARGARGARGARGARATGTAYGARMGNMGNAARYTNGARAAR AARYTNMGNGARAARGARGCNGCNTAYCARGARMGNYTNAARAAYTGGGARGGNMGNGAR MGNAARAARTCNMGNGARTAYGARAARGARAAYGAYMGNGAYCARGARMGNAARGTNGAR GARGGNMGNGARGGNMGNMGNYTNAARGARTTYYTNGARGAYTAYGAYGAYYTNMGNGAY GAYCCNAARTTYTAYAARGGNGGNGCNYTNGCNMGNMGNCARAARGARMGNGAYAARGAR AARGARATGGAYAAYMGNGAYMGNCARMGNGARAARGARGARTTYGARGARATHAARMGN AARYTNTTYGAYGARGGNCAYCCNCAYGCNGARACNGARGTNGCNMGNATGGARMGNGAR MGNGARGARCAYYTNCARCCNMGNYTNCAYYTNCARGARATHAARGCNAAYAGYCCNGCN ACNCARCCNGAYATHTCNGARTCNGAYTCNGARCCN------------------TCNCCN GARGARAARYTNCCNACNTCNCCNAARCAYGCNCCNCARCAR------------------ ---------------CARAARAAYGTNCAYCARCARCAYACNYTNGTNCARGARACNAAR AAYTCNCCNTCNYTNTCNACNTCNCCNATHTCNACNGAYTCNMGNGTN---AGYGCNCCN GGNYTNTTYGTNGAYGARTCNTCNCARTCNTCNYTNCCNCCNGTN------CCNTCNYTN CCNYTNCAYAAR---GARGARGCNMGNGTNGGNGTNGGN--------------------- AGYAARCAYYTNGCNCCNAGYGTNAGYCCNGAYTCNTCNAGYYTNCCNGGNGCNAGYGTN TCNYTNGARGGNAARMGNAARAARYTNACNGTNGGNGAYGTNTTYAAYCARGAYGAYGAY GAYAGYAAYGARCCNAARAARMGNAARYTNATHCCNYTNGTNTAYGAYGAYGAYAARTCN ACNCCNACNGAYAARAARACNGCNACNGCNGARGARAARMGNCARAARATHAARCARYTN ATHGARAAYATHCCNACNGCNAARGAYGARYTNTAYGARTTYGTNGTNGAYTGGGAYATH GTNGAYCARAGYYTNATGGAYAARMGNATHAARCCNTGGGTNACNAARAARATHATHGAR TAYATHGGNGARGARGARCCNACNYTNACNGAYTTYATHTGYCARAARGTNGTNGCN--- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TGGCCNMGNGARGGN AARCAYATHYTNGCNCAYTAYGAYGAYGAYACNATHGTNGTNTAYCARGCNTTYAAYMGN GCNATHGCNGAYTAYGCNGTNCARCAYCARAARTTYGGNGGNCCNGCNTAYAAYCCNGCN MGNATGTCNTGGATHAARACNAAYTTYATGTGGATGATGTTYMGNTGYGGNTGGGCNCAR AARCARAAYCARGARMGNGTNYTNGCNATHMGNATHACNAARCARGGNTTYGARGARATH YTNTCNATHGCNMGNTCN---TCNAARAAYYTNGAYMGNAGYGCNGARGGNGAYAGY--- ACNGTNMGNYTNCARTGGGAYCCNGAYCAYTGYCCNMGNGGNGAR---AARYTNACNMGN MGNGCNATHCARYTNGGNYTNAARGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GARGARGARGCNTTY TAYGARGCNAARMGNCARGCNGCNMGNATHGCNAARYTNAAYAARATHAARGARGAYGCN YTNAARACNAARGGNACNAAYGCNTGGGCNGGNAAYGARGAYGARTGGGARGTNGCNGGN GGNGARGAYGAYTTYGARATGTTYYTNGCNAGYGTNAARGCNMGNTCNYTNGCNACNMGN TCNCARGTNAARGAYGGNTCNGGNGAYGCNCARAGYTCNAGYAGYAGYAAYGCNCAYACN AARGCNAGYTCNYTNGAYATGGARTGGGARCAYGARTCNGGNATGTCNCCN---CCNMGN MGN---CCNTTYCARGTNTCNGARGAYAAYTGGTCNAARACNTCNACNGCNAGYCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CAY YTNATGGTNATGTGYTGYGTNYTNMGNTAYATGATGCARTTYGGNMGNYTNYTNCARMGN CARGARYTNGAYGCNTTYYTNGCNATGTCNGTNTCNCCNYTNYTNCAYGAYGTNCARACN ATGCARGAYYTNAARYTNCCNCAYATHYTNCCNMGNGGNAGYCARYTNGCNTCNYTNTTY ATGGCNGGNATHGARACNTCNAGYATGGCNAAYGAYGTNTGYGGNGCNCCNATHCCNTGG ACNATGATHTGYCCNTGGYTNTAYATGGAYGGNAARYTNTTYCAYTTYAARYTNYTNAAR GCNAAYAAYAAYACNCCNYTNATHGAYATHTGYGAYGGNMGNATGGARCARGTNYTNMGN GTNGARMGNATGMGNCARGCNATHYTNGARAAYYTNCAYGTNGAYTTYGCNAARCCNYTN YTNCCNAGYTTYTAYTAYCCNTAYCCNGGNCARCCNTAYCCNAGYGGNCCNYTNCARTAY GGNTCNCCNGGNTCNCCNMGNGGNMGNGGNGGNCCNCCNGGNMGNACNGCNGGNMGNGGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AAYACNGAYGTNCCNCCNYTNGARGAYATGACNGAYGTNYTNAAR CARGTNGAYGCNATHMGNGARCAYMGN---CAYGGNAGYGCNAGYAAYGGNGCNAARTCN GTNACNAAYAAYCCNAARGCNAARGCNAARGTNAAYAARAARAGYYTNCCNGCNCARAAR ATHACNCCNYTNAARAARACNGARCCNGARTCNAGYAGYGGNGAYGTNACNACNCCNAAR AAYGARACNYTNAARGCNGARAARGCNAARGARGCNATHCCN------------------ ---TCNACNAARAARCCNCARAGYTCNTCNGGNTCN---TTYGGNGGNATGAARAARGGN TTYATGTTYGGNGGNCCNCCNTCNAARAGYYTNCCNGCNCCNAARACNGAYAARGTNGCN AGYGARAARGARACNAAYGCNAARAGYCARAAYAGYYTNCCNCCNGCNCCNAARGCNACN ACNACNAARAAYGARGCNGAR---GARATHCCNTAYATHACNAARAAYGGNAARAGYGAR TCNGGNYTNTCNYTNAAYGARGTNCARCARGCNATGTCNGARGCNAARGGNYTNATGGAY AAYCAYGAYTGGATHACNGAYGAYTTYYTNAAYAARATHGARAAYAAYGARYTNYTNGTN AARMGNTTYGGNGAYCCNCAYTTYATGGARGCNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGTCNGARAAY------AARGCNAAYAAYGTNTCNTCNYTNYTN YTNAGYGAYCARGARAAYGARACNYTNTTYMGNATHYTNGGNAAYTTYGGNACNACNYTN GCNACNGGNGTNGTNCARYTNTAYYTNTCNGAYTCNGTNGAYCCNMGNMGNTGGACNAAR MGNTGYTGYGGNGTNGCNTGYTTYGTNAARGAYAGYTCNAARMGNTCNTTYTTYATHMGN GTNTTYGAYATHAARAARGGNTCNATHATHTGGGARCARGARYTNTAYTCNCARTTYGTN TAYAARGCNCCNMGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GGNACNACNGTNGGNAAR GARGCNYTNAAYGGNAARACNGTNGGNATHTAYTGYTCNGCNCAYTGGTGYCCNCCNTGY MGNTCNTTYACNCCNAARYTNGCNTCNTTYTAYGAYGCNTAYAARAARYTNGAYCCNAAY TTYGARATHGTNTTYTGYAGYAGYGAYAARTCNGARAARGARATGATGTCNTAYTTYAAR GARGCNCAYGGNGAYTAYYTNTGYTAYGARTAYGGNTCNAARCARMGNGARACNATGAAR AARATGGTNGAYGCNTCNGGNATHCCNACNTTY---GCNATHTAYAARGAYGGNAARYTN GTNAAYAARGARGGNMGNTCNAARGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------NNNNNNNNNNNNGTNATGMGNAARCCNTAYAAYGAYAAR GARGAYACNTTYGAYGTNCARGAYYTNGCNGCNAARGARCCNTTYAARCARTTYTCNGTN TGGTTYGARGARGCNAARGCNAAYGAYGGNGTNACNGARCCNAAYGCNATGGCNYTNGCN ACNGCNACNAARGAYGGNAARCCNTCNGTNMGNATGGTNYTNYTNMGNGGNATHGAY--- ACNGGNTTYATHTTYTAYACNAAYTAYYTNAGYMGNAARGCNCARGARYTNGAYGARAAY CCNCARTGYTCNYTNGCNTTYTTY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CARMGNCAYATHGARMGNYTNCCNGTNATGATGGGNMGNCARGCNMGNATHCARTTYCAR TCNTAYYTNGAYGGNTTYGARGARGCNGTNGARGGNATHYTNGCNATHGCNACNACNAAR CARGCNGTNYTNTCNGAYGARGTNGTNTCNTAYGCNCAYGTNGCNATHGTNAARGARGCN GARGAYGTNAARTGYATHAARTTYGAYCARGARCAYMGNTGYGCNGTNAGYATGCCNATH GARAARGTNGARGCNGAYYTNAARATHGGNCCNTGGAARAARAARMGNGAYGAYGTNACN GAYMGNGTNTAYYTNMGNGCNGTNGCNMGNGARATGGARGCNMGNGGNTTYACNGTNACN TTYTCNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MGNGGNTTYMGNMGNAARCARACNGGNGCNGTN MGNGARGTNAARCCNTCNAAYGAYCARGARGGNTCNTCNTTYTCNATGTTYAARTCNYTN ACNTTYGTNACNGGNGTNTGYAGYTGYAGYTTYGTNGGNGCNATGATHTGGAAYTAYGAR CAYATGMGNMGNGTNTAYAARCARATGGGNAARTCNAGYGTNGARGARAGYAAYCAY--- ---------ATGGAYAARTCNTTYGGNTTYMGNCARCAYGCNAAYTCNYTNTGGAARAGY TTYAGYGCNGGNCARACNYTNATHTTYGGNATHATHGCNGCNAAYGTNGCNGTNTGYYTN YTNTGGMGNYTNCCNTCNATHCARCCNACNATGYTNMGNTAYTTYTCNTCNGCNGCNAAY CAYCCNATGTCNTCNATGYTNYTNAGYAGYTTYAGYCAYATHAGYTTYATHCAYYTNTTY GTNAAYATGTAYGTNYTNYTNTCNTTYGCNCCNGTNGCNACNAARGTNTTYGGNCCNGAR CARTTYTCNGCNTTYTAYYTNAGYACNGGNACNATHTCNGCNTTYACNAGYATH------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARAARATGATGGARGARMGNAAYGARCARGCNGARAARATGGCNATHGCNAAYATGMGN CARGAYGCNGTNCAYAARCCNGTNGGNATHAARMGNTAYMGNAGYGTNATHGTNAARCCN AGYGAYAARCCNGTNACNGARCCNTGYTCNCCNMGNTTYTCNGARMGNACNMGNTCN--- ------------------------GAYCCNAAYGAYGARCAYGGNGGNGTNCCNATGGGN ATHCCNGAYTCNTTYTGYGAYGAYGGNCARACNGCNATHTCNATHGAYTAYGAYCCNMGN TCNACNGARGARTTYACNTGYACNGAYGGNATGMGNTCNGCNAGYACNGAY---CAYGTN ---------CAYCAYTTYCAYTGYAAYAARACNGCNGAYAARCCNGTNCAYGTNTGYYTN CCNGARCCNATHCAYTAYGCNGTNGAYYTNCCNACNAGYGGNMGNCAYMGNCCNYTNTGG CCNGTNTAYGGNGARTAYAARTAYYTNCCNGTNCARMGNTGGYTNCAYTCNYTNGARCAY GGNGCNGTNGTNTTYYTNTAYGAYCCNTGYGCNGAYGARAARGARGTNAAYCARYTNMGN YTNYTNGCNAARGGNTGYYTNMGNMGNCAYATHATHACNCCNAGYAARAARYTNCCNCAR GGNATGAAYTTYGCNYTNYTNTCNTGGACNTGYAARCAYGTNTTYAGYAAYTTYGAYGAR GCNAARATGGTNCARTTYGTNATGGAYCAYGCNATHGAYGCNCCNGARAARAGYGTNTTY AGYGAYGGNCARTAYATHGCNAAYAAYACNGARAARGCNAARACNGTNACNGAYATHCAR GAYTCNGARYTNTGYCCN------------------------------------------ ---------------------------------GTNGAYGAYGCNATHGGNMGNGTNGCN AARATHMGNAARMGNCARCCNACNMGNTGYTGYGAYATHGCNACNAARGTNGCNAGYAAY AAYATHCARTAYTAYAGYATGGTNACNGTNAARGAYGAY---------------MGNATH AARGTNAARAARGAYGARATHMGNGTNGGNCCNAARTCNTTYACNTCNGCNACNGAYGCN YTNYTNGCNTAYYTNGGNCARTTYGARCARGAYGAYCCNGGNAGYGGNGARAGYACNCCN MGNGGNGTNAAYGGNAAYGGNGARGCNAGYGAYMGNCARGTNGCNGTNGGNGCNAAYGGN YTNMGNYTNGARGGNGCNAARGARGARGTNGARACNYTNYTNACNTCNCARGTNACNCCN CARYTNMGNGARGARGTNACNGAYACNYTNMGNGARGTNAARYTNMGNCARYTNYTNAAR CARGCNGCNMGNAARTCNCARAARCARAGYAARACNGGNYTNCARCARGARGTNGARGCN GCNYTNACNMGNTCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNACNGTNCARGTNCAYCARYTNGAYGGNAAYTCNGCNTTYCCNTTYTCNGGNMGNGAR GGNCARATHGCNTGYAGYGTNGARCARAARGTNTAYGTNTTYGGNGGNGTNGARCARGGN CARGGNGAYGARCCNAARGARACNAAYGAYYTNYTNATHTTYGAYGCNGTNCAYAGYAAR TGGTCNAARCCNGAYATHCCNGGNYTNAARCCNCCNCCNMGNTCNGCNGCNTCNYTNGTN GCNGTNGGNACNAAYYTNTAYYTNTTYGGNGGNYTNAGYCAYATGTGYGGNTGGTTYGAY GAYGTNCAYGTNTAYGAYACNGARAARMGNTCNTGGGCNATHGTNGARACNGARGGNATH AARCCNMGNGCNMGNGAYAARYTNCARGCNGTNGCNTTYGAYAAYAGYATHTAYTAYTTY GGNGGNTTYGGNCCNAARTCNGAYGARGCNGARGTNGAYGAYYTNGCNAGYGAYGAYGAR GAYGAY------------GARGAYATHCCNGARTCNMGNGAYCARCARGGNGCNGARTTY GGNTGGTTYAAYGAYYTNTAYATHYTNGAYACNGCNAAYMGNAARTGGTCNCARCCNATG CARATGAAYYTNGGNGTNCCNACNCARMGNGCNGCNCAYGGNATGTGYGCNATHGGNMGN AAYYTNGTNATHTTYGGNGGNMGNGAYTCNGARGAYMGNCARAAYGAYATHCAYATHTTY AAYATHGAYACNMGNAARTGGATGYTNGAYTTYAARGTNGARGGNGTNGCNCCNGARCCN MGNTCNTTYCAYACNYTNACNTCNGTNGGNGGNMGNGCNGTNGTNTGYGGNGGNMGNGGN MGNGAYAAYAARCAYTTYTCNAAYTTYGTNATHTTYGAYYTNGARCAYAARGARTGGATH CCNGTNACNTCNGARGGNTAYCARCCNCCNGGNMGNGGNCARCAYAGYTGYGTNACNGTN GGNGAYAARYTNYTNGTNATGTGYGGNTCNGGNGARTTYAGYCCNGARATHATGCARTGY AARTCNTTYTAYACNGAYGTNTTYGARGTNCCNATHGGNGAYTTY---AGYGGNGARAAR AARTCNAAYGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG CAYYTNCCNGCNGAYYTNAGYGGNTTYACNCCNTAYCARGAYTTYAGYATGTCNGARATH GGNGTNGTNCCNGGNGAYMGNCCNYTNACNTGYGTNYTNAAYGAYCAYCCNGGNGARYTN GTNAARACNGGNAGYCCNAAYTTYYTNTGYTCNATHYTNCCNTCNCAYTGGMGNTCNAAY AARACNYTNCCNGTNCCNTTYAARATHGTNGCNYTNGGNGARGTNAARGAYGGNACNAAR GTNTGYATHACNGCNGGNAAYGAYGARAAYTTYTGYTCNGARYTNAARAAYAAYCARACN TCNATGAARAAYCARGTNGCNAARTTYAAYGAYYTNMGNTTYGTNGGNMGNAGYGGNMGN GGNAARTCNTTYACNYTNACNATHGCNGTNTTYACNAAYCCNCCNCARTTYGCNYTNTAY CARAARGCNATHAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATHGAYAAYMGNGTNCAYMGNYTNCCNGTNATHGAYGARATHACNGGNAAY GCNYTNTAYATHATHACNCAYAARMGNATHYTNMGNTTYATGTAYYTNTTYYTNAARGAR YTNCCNCARCCNTCNTAYATGMGNCARTCNYTNAARGARYTNGGNATHGGNACNTAYGAR AAYGTNATHACNGCNACNCCNGAYATGCCNYTNATHMGNGCNYTNAAYYTNTTYGCNGAR CAYMGNGTNTCNGCNYTNCCNGTNATHGAY---CARAAYGGNAARGTNATHGAYGTNTAY GCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARGAYAARCARGGNMGNMGNMGNTTYCAYGGNGCNTTYACNGGN GGNTTYTCNGCNGGNTAYTTYAAYACNGTNGGNTCNAARACNGGNTTYAAYCCNTCNACN TTYGTNTCNTCNMGNAGYAAYAARGAYGAYGCNTCNGCNAGYACNMGNCCNGARGAYTTY ATGGAYGARGARGAYYTNGAYGARCAYGGNATHGCNCCNMGNMGNATHGCNACNACNGAY CAYTAYTCNTCNGARTCNMGNAARMGNAARTTYGARGAYGTNAAYAARMGNGCNACNGCN GAYYTNCCNATHAAYYTNAGYTCNTTYYTNCCNAAYYTNATHGTNGCNGARCARYTNTCN ATHGGNATHMGNYTNYTNMGNAARATGGGNTGGMGNGAYGGNCARGGNYTNGGNCCNMGN ATHMGNAARAARAARAARAARAARTCNAARGCNCAYCARGCNMGN---GTNAARGTNTAY GGNTGYGCNYTNCCNCCNTCN---GCNAGYGARTCNGARGAYGAYAAYTAYGTNCCNGCN GGNTTYGARGARGCNACNTTYGCNCCNAARGAYGTNTCNTCNGTNATHATGCARGCNAAR GAYGAYATHAARGGNYTNGGNTAYMGNGGNATHGAYCCNAGYYTNGCNYTNCCNGGNTCN CAYAARAARCCN---GAYGTNTCNGTNAARTTYGGNCAYGGNAARAARGGNATHMGNGGN CARGCNTTYGGNGTNGGNGCNTTYGARGAYGARGAYGAYGAYGTNTAYGGNCAYGAYGAY ATGTCNAAYTAYGAYTTYACNYTN---MGNGGNGTNGAYGAYGGNGARAARYTNTTYGGN TGGACNGCNCCNMGNTCNCAYGCNGAYGARACNACNCCNGCNTCNTAYGTNGGNAARGTN YTNTCNGGNTTYTGYYTNGCNAARAARCCNYTNAARCCNGCNAARAARTTYAGYCCNCCN ACNYTNCCNAARCAYTTYMGNCCNCARCAYTGGTTYMGNAARAARMGNATGGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNCAYATHGARAAYMGNGTNAARTAYAGYTTYGAYGCNGCNMGNATHATGTTYAGY AGYGGNAAYACNACNGARMGNGTNAARATGGGNGARYTNACNACNCCNGGNGARACNGTN ATHGAYATGTTYGCNGGNATHGGNTAYTTYACNYTNCCNATHGCNAARAAYGGNGGNATG ------GTNCAYGCNYTNGARAARAAYCCNGTNAGYGCNGARTTYYTNGTNAARAAYGCN GCNYTNAAYGGNGTNAGYGAYMGNGTNCAYGTNCARAAYGGNGAYAAYMGNGARATHGAR YTNYTNGGNACNGCNGAYMGNGTNTCNATGGGNTTYTTYGAYGGNAARGARCCNTTYATH CCNMGNGCNATHTCNTTYYTNAARCCNAGYGGNACNGTN---CAYTAYCAY--------- ------------TAYGTNGGNCAYCAYTAYGCNGGNCCNGGNAAYCAYTTYTGGAARTAY GAYGAYTTYAARYTNYTNGARCAYGGNGTNGGNTTYACNAAYGTNTGYGCNMGNACNACN MGNGGNAGYGCNGAYYTNMGNMGNAAYGARATHAARGARGGNGCNGARATHYTNAARMGN AARYTNYTNAARTAYAARCCNAARATHGCNGTNTTYAAYGGNAARGGNATHTAYGARGTN TTYAGYGGNAARAARGAYTTYACNATHYTNACNATGGTNCARAARGARAARGTNYTNMGN ACNMGNGTNGAYGCNTAYACNAARGARAARACNGARMGNATGACNAARTAYMGNGARYTN CAYAAYAARGAYCARYTNTTYTGYGARTCNYTNGARACNGTNCCNTAYTTYYTNCCNCAR GGNACNATHCCNTCNYTNGARCARYTNAARGARYTNGARACNCAYGTNAAYAGYATGCAR ATHGARAARAGYAARMGNYTNTCNACNTTYACNGAYYTNAARAARAARATHTGYGAYTTY TAYAAYGARATGGARTGYGAYCCNGAYTCNTCNTTYTCNMGNGARGTNGTNTGYGARGAY GAYGAYGCNTTYACNYTNTCNGARMGNAAYYTNGAYCAYYTNAARCARYTNCAYGARMGN YTNGTNGCNAARAAYCARAAYATGAARGAYGARGTNGARGAYATGTGGGAYMGNYTNMGN GCNYTNTGGAAYMGNYTNGARACNTCNGAYATHTGYMGNGARGCNTTYGARYTNGGNAAR GARGGNCAYAGYACNMGNATHATHGCNGCNYTNAARGCNGARATHGARACNTGYGARCAR YTNAARYTNCARAAYATHMGNAARTTYATHGARGGNATHMGNACNGARYTNGARACNTGG TGGAAYAARTGYTTYATHAGYYTNGTNGARMGNAAYAARTTYACNCCNCARAAYGARGAR AGYTAYACNGARGARYTNYTNYTNGTNCAYGARAARGARYTNGARTCNYTNMGNGARTAY TAYAARACNCAYAARGAYYTNTTYGAYAARATHGCNAARMGNGARGAYYTNTTYAARAGY ATGGTNATGTTYGARGARAARGCNAGYGAYCCNAAYMGNTTYTTYAAYGAYMGNGGNGGN AARYTNYTNCARGARGARAARGCNMGNAARMGNATHGCNAARGARYTNCARAARGTNGAR GARGARGTNACNGAYATHGTNYTNAARTGGGARGCNGARAAYGAYAARGARTTYYTNGTN AAYGGNGTNMGNTTYACNACNTAYACNGARACNCARTGGAAYGAYTGGCAYATGAAYAAR GARCARGARAARCARAAYMGNGTNAARGCNMGNACNAARCARATHCAYGAYGARGCNATG TTYGGNAGYAARTCNGCN---GCNGTNCCNAAYAARMGNAARGTNGGNAAYGCNTCNACN CCNGTNMGNACNCCNYTNAARGCNMGNAARATGAAYGARGCNYTNAARACNCCNAAYACN ACNAGYMGNYTNCCNAAYMGNAGYAARATHCARCAYAGYACNATHGTNCAYTCNTTYCCN YTNTAYACNCCNAARACNCCNYTN---GGNTCNACNAARAARMGNMGNTCNYTNMGNYTN ATGAARAARGCNGCNACNGARMGNAARYTNAGYACNAGY---MGNMGNAARYTNCAYGGN ACNTTYTCNCARACNACNGTNAGYGGNCAYGGNCAYGGNCAYTCNACNYTNGARACNACN GTNTCNTAYAARGAYTTYTCNAAYGGNYTNTCNMGNCCNGAYTGYMGNAGYAGYGTNATG GCNTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNYTNGARGCNYTNGARTCNAARTCN GGNCARACNCCNGARGTNAAYGAYGARGCNYTNAARGTNTGYAAYGARATGTCNAARGCN YTNGGNATHCCNCCNACNGGNYTNCARCCNGGNGCN---------------TCNTGYTCN GGNATHGARGARGAYYTNGAYGTNGARCCNAARTCNCARCCNCCNAGYACNTCNGGNCAR GARAAYGAYGARGGNAARTCNGAYGARAARGCNGARTCNTGYACNGCNGTNTCNGCNGTN GARMGNMGNTCNGGNTCNTCNGAYTTYATHGAYGTNTCNGARGARGARTTYYTNTCNGTN TCNGAYYTNATHMGNCARMGNGTNAARYTNGARGARGTNAAYAARGTNTAYGARCARYTN TGGCARCAYTTYAARGARGARGGNAAYACNAARCCNYTNACNGTNAARGAYATGACNAAR ATGGGNATGMGNGTNACNGGNGCNACNGGNCARGCNAARYTNAARGTNYTNMGNGCNYTN AARYTNTGYCARATHAGYMGNACNGGNGAYGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TTYATHCCNGTN GCNCARACNGTNCAYYTNACNTCNGCNTTYYTNYTNACNYTNCCNGARATHYTNYTNACN GCNAGYAGYGTNGCNTGGGARAGYGARYTNGAYATHYTNTTYCCNGTNTAYMGNTCNGGN YTNAGYCAYACNYTNAGYACNGTNAAYYTNACNYTNTAYCCNAAYGTNACNMGNTTYGAY GTNTCNATHCCNMGNMGNACNGAYTTYTAYAGYGGNGAYMGNGTNAGYATHAGYGTNGCN TTYATHCAYTTYTGYATGGCNYTNGTNTGYTTYYTNGTNMGNTAYGCNTCNGTNTTYTGG TAYACNAAYAARGCNYTNACNYTNGTNTTYGCNACNCARYTNYTNGCNATGGTNATHAAY TGYATHTTYGGNATHAAYTGYTTYGCNGTNYTNTAYTGYGTNTGYTTYAAYCARAARATG TAYCCNAAYGTNCAYYTNTCNYTNTCNTGYGGNATHGAYYTNACNYTNTTYYTNATHGGN AAYGCNATHGTNATHYTNTCNACNATGACNTTYTTYGARTAYGGNTCNCAYTAYTTYTAY GARAARTCNAARATHGTNGAYMGNCARCAYTGYACNGAYAGYTAYGTNAARCARACNGTN ATHGTNAAYAGYGGNTGYCARGGNTAYGCNCCNCAYTCNYTNGCNATGYTNTCNYTNGTN GTNTTYGCNGCNTGYAARGGNCCNYTNATHTAYGAYYTNGTNGCNYTNATGTCNAARACN GGNGAYCAYYTNATHATGGCNGGNATHGTNTGYGARGTNTGYTAYATGGTNTTYTGGYTN GCNYTNTGGTTYGGNYTNACNGTNAARCARAARTGGCARTTYMGNATHYTNGAYTAYYTN TCNYTNMGNCARYTNGGNMGNGAYCARGARGCNCCNTGGMGNGGNACNAARTCNGCNAAY CARGARTCNGCNTCNAARGARTTYMGNAAYAGYATHMGNAAYAARTGYGCNGARTAYTAY TCNGCNGCNAAYAAYGTNCCNCCNGARYTNGCNGAYATGACNACNYTNATGTCNTCNTTY MGNGAYAARGTNMGNGARTCNTCNYTNGCNGCNAGYAGYTTYAARGARMGNGARMGNCAY ATGYTNGARAGYTAYCARGAYAGY---------------------------------TTY TTYGAYGTNCCNTGYGARGTNYTNGCNAARGCNYTNYTNGGNCARMGNYTNGTNMGNACN GTNGGNTCNGTNMGNYTNTCNGGNMGNATHGTNGARACNGARGCNTAYYTNGGNAAYGAY GAYAARGCNGCNCAYAGYTAYAARGGNAARMGNACNGARMGNAAYGARGCNATGTTYATG AARCCNGGNACNGCNTAYGTNTAYAAYATHTAYGGNATHTAYTGYTGYATHAAYATHTCN AGYCARGGNGAYGGNGCNGCNGTNYTNATHMGNGCNYTNGARGTNGCNGARGGNAARCAR GARATG---------ATHATHGCNMGNTCNAARAAR------TCNTCNAARCCNAARAAR GAYAARGARYTNACNAAYGGNCCNTCNAARYTNTCNCARGCNYTNCARATHTCNAARGGN GARTTYAAYAARACNGAYATGACNGTNTCNGAYTCNYTNTGGYTNGARAARGAYACNGAY ATHAARCCNTCNCARATHGTNACNTCNGCNMGNATHAAYATHGTNTAYGCNAARGARTGG ACNAGYAARCCNYTNMGNTTYTAYATHYTNAAYAAYGARTTYGTNAGYGTNMGNGAYAAR AARGCNGAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CARMGNTTYAAYCCNACNGGNAAYTTYAAYGGNCAYTGYGGNAARTAY AARATHACNGGNAAYTAYGCNAARTGYCARCAYCAYGAYATHTCNTGY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TCNYTNATGGCNGARTAYGAYCARYTNCAYCARCARAARNNNCCNGGN GTNTAYACNATGCCNTGYTCNAARTCNCCNYTNATHTGGAGYGGNYTNATHTTYGTNMGN CARGGNYTNTAYCARGGNGCNGCNYTNMGNTTYACNYTNACNATHCCNGAYAAYTAYCCN GAYGGNGAYTGYCCNAARTTYGCNTTYGARTAYCCNGTNTTYCAYCCNYTNGTNCAYCCN GAYACNGGNAGYYTNGAYGTNAARMGNGCNTTYCCNMGNTGGMGNMGNAAYGTNAAYCAY YTNTGGCARGTNYTNYTNTAYGCNAARAARATHTTYTAYAARGTNGAYACNAARTCNCCN YTNAAYTCNGARGCNGCNGTNYTNTAYGAYCARGARCCNGAYYTNTAYAARGTNAARGTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARCCNTTYYTN TAYYTNGCNTAY------------CARTCNGTNCAYTCNCCNYTNCARTAYTAYGARCAR ------------------------------------CARTAYTCNAAYATHCARGAYAAR TCNMGN------------------------------------MGNGCNTAYGCN------ ------------------------------------GGNATGGTNTCNGCNATGGAYGAR GGNATHGGNAAYYTNACNCARGCNATGAARGAYTCNGGNYTNTGGGAYAAYACNYTNYTN GTNTTYTCNACNGAYAAYGGNGGNCARATHYTNGARGGNGGNAAYAAYTTYCCNYTNMGN GGNTGGAARGCNTCNYTNTGGGARGGNGGNYTNCAYGGNGTNGGNTTYGTNTCNGGNGGN AARGARAGYCARMGNGGNGTNATHAAYCAYGARYTNATHCAYGTNTCNGAYTGGTTYCCN ACNYTNGTNGGNYTNGCNGGNGGNAGYYTNAAYGGNACNAARCCNYTNGAYGGNTAYGAY CARTGGGAYACNATHAGYTCNGCNGCNAARAGYCCNMGNAARGTNYTNYTNCAYAAYATH GAYATHYTNCARNNNAARAARGGNATHMGNYTNTAYAAYGAYACNTTYGAYACNMGNGTN MGNGCNGCNATHMGNGTNGGNGAYATGAARYTNATHACNGGNGAYCCNGGNAAYAGYTCN TGGATHCCNCCNCCNGAYGAYAARCCNGARGTNMGNGARGCNTCNGCNAARAAYYTNTGG YTNTTYAAYATHACNGCNGAYCCNAAYGARCAYGTNGAYYTNTCNGAYTCNATGCCNTCN YTNGTNMGNTCNATGYTNGAYYTNYTNGTNAARTTYAAYGAYACNGCNGTNCCNCCNMGN TAYCCNCCNCCNGAYCCNMGNTGYAAYCCNGCNYTNCAYGGNGGNGTNTGGGGNCCNTGG ---------------------------GTNAARMGNGARAARAGY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARACNMGNATHCAYGARGGNCAR ACNACNCARATHCAYTTYTTYYTNCCNCARYTNGCNGAYGGNATGAGYGARGCNTCNGGN CCNGCNACNAGYMGNAGYTTYTAYCARGAR---MGNYTNGAYYTNYTNAAYMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CARCAYMGNYTNTCNGGNCARAGYTAYGARTCNGGNGTN TCNTCNMGNCARAGYTAYCAYAGYACNAGYAGYTCNAGYCAYGGNAGYYTNGAYMGNYTN GARGAYCCNGGNYTNCCNTCNACNATHAAYGTNGCNCARYTNTTYCARGCNGGNGTNCCN GAYACNGARGTNYTNCAYGCNTGGYTNCAYGAYYTNCAYTTYGARGARTAYTTYCCNYTN TTYACNCAYGCNGGNTAYGAYATGCCNACNATHTCNMGNATGACNCCNGARGAYYTNACN GCNATHGGNATHACNAARCCNGCNCAYMGNAARMGNYTNAARGCNGARATHGCNMGNYTN CAYATHCAYGAYGGNATHCCNGAYTAYMGNCCNAAYGAYYTNATGGARTGGYTNCAYYTN YTNGGNYTNGGNACNTAYYTNGARACNYTNTGYGGNCARGGNTAYGARAAYATHGAYGAY GTNACNGAYATHACNTGGGARGAYYTNGARGARATHGGNATHCARAARYTNGGNCAYCAR AARAARATHATGYTNGCNATHGAYMGNYTNAARMGNATHACNTCNGGNGCNAARMGNYTN TCNACNGTNGAYGGNMGNACNGCNTCNYTNGARYTNYTNGARCCNCCNCCNCCNGCNCCN CCNATGGCNMGNTGGTCNGGNGARATHACNGCNATHCCNATGGTNGARGCNGAYGTNTCN CARGGNGAYYTNGAYCCNGAYAARMGNGCNGCNYTNGARACNATHATGGARGARYTNATH GAYGARGTNACNYTNGGNYTNTGYTTYGARATHCAYMGNTCNTGYAARATHGGNTCNYTN TTYYTNAAYGTNTTYGAYGAYACNTCNGAYACNGARTAYGCNATHGTNGARMGNCCNGGN TTYGAYGTNYTNGGNCARATHCCNTCNAARAARAAYTAYGARTGYGTNTGYCCNAAYTGY CARMGNCAYYTNGCNGCNTCNMGNTTYGCNCCNCAYYTNGARAARTGYATGGGNATGGGN MGNAAYTCNTCNMGNATHGCNAGYMGNMGNATHGCNAAYAAYCARAARCAYGGNAGYGAY GARAGYGGNCARGAYGAYGARAAYGAYAAYGAYTGGAAYTAYGCNCCNGAYTCNMGNMGN ATHMGNAARYTNAARAARGAYAARATGTCNAAYTCNCCNMGNAAYMGNMGNYTNGCNAAR YTNMGNAAYGGN------GGNTCNAGYCARGAYTCNACNACNCCNGTNGCNCCNGTN--- ------------------------------------------------------------ ---------------------GAYTCNTCNGARGCNCARGARTCNACNYTNAAYTAYGAR TCNATGAAYATHGARGAYMGNAARGCNYTNYTNATGAAYAGYTGYGGNGTNATHTCNGAR CAYACNAARAARATGTGYACNMGNACNGGNAARTGYGTNCARCAYACNGAYGARCARMGN MGNYTNGTNMGNCARAAYYTNYTNMGNCAYAGYGGNGCNCAYGAYATGGARGAYATHCAY ATHGAYATHGAYACNTAYGAYGAYGCNGARTCNCARTCNYTNMGNGARTCNYTNCARTGG GARGCNTCNTCNAAYTCNTCNCCNGCNGAYTCNACNTCNACNAAYAAYAGYACNTCNGGN TGY---------------------------MGNCCN---AAYAARAGYTCNGGNAARCCN AGYAARGTNAARAARCARAARACNGTNAARTCNGGNATHTCNACNTTYAAYAAYGCNAGY GCNAAYAARGAYCAR---AGYACNAAYATGTAYGARTTY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TAYYTNGAYACNGARTTYGARGCNYTNGTNCARGAYGGN--- CARAGYAGYTCNYTNTCNGAYTTYMGNAAYTCNYTNATGGCNTGYGGNGGNTAYGGNGAR GARGARGAYATHTAYCARYTNCCNGTNYTNTCNGARTCNTTYTGYMGNGARYTNATHGAR GARYTNTCNCAYTTYGARGARAGYTCNTGYCCNAARGGNMGNCCNAAYACNATGAGYAAR CAYGGNATHTCNYTNGAYGARATGGGNYTNTCNGAYAARACNGTNACNATGYTNGTNTCN GAYYTNYTNMGNCCNYTNTGYAGYYTNYTNTAYCCNGARCAYGGNGGNGAYTCNYTNGAY TCNTTYAARGCNTTYGCNGTNYTNTAYGGNCCNGAYAARGAYCARCARYTNTCNACNCAY TTYGAYAAYGCNGARGTNACNATHAAYATHTGYYTNTCNCCNTCNTTYACNGGNGGNGAY YTNGTNTTYGGNCCNMGNTGGAARGAYAGYGGNGARGGNGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MGN AAYMGNATGCCNMGNATHTGYACNAAYMGNGTNAARYTNMGNCCNAAYAGYCARCCNATH GGNTAYTTYATHTGYCCNYTNYTNGAYGGNAAYCARYTNYTNGCNTAYTGYTGYGGNCCN AARGGNGCNGARTTYTGYTGYGAYGARTAYTCNGCNAARAARTTYTAYTGGGAYCAYAGY AARTCNGGNGGNGGNGTNTCNGTNGGNGCNATHGTNGGNATHGTNATHGTNATHGTNYTN GTNATHGTNATHGTNTTYATHTGYTGYAARMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNYTNGGNTAYYTNATGGARAARYTNGARGAR AARGAYGTNYTNGAYGAYATHAAYATHATHGTNACNAGYGAYCAYGGNTTYACNGARACN CCNAARAAYAARATHATHTTYYTNGAYAARATHATHGARCCNAARATGTAYAARGCNGTN CAYTAYACNCCNGTNYTNACNATHATHCCNAAYAARGGNTAYGARGARGAYGTNTTYAAY AAYYTNAARACNGCNAGYGTNAAYAAYCAYTTYAAYGTNTAYAARAARGARGARATHCCN GARMGNYTNCAYTAYAARAAYAAYCAYMGNGTNACNCCNATHGTNGCNATHGCNGAYYTN TCNTAYTCNTTYYTNGGNAAYATGGGNATHGAYAARTTY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNGCNYTNAAYTAYACNGCNAGYATHGAY GGNGAYCARTGGAARGGNGARGCNATHYTNCCNMGNGARTAYTTYCCNCCNAAYGTNACN MGNTTYAAYGCNTTYGCNATHCAYGGNGARGGNACNGCNMGNCARTAYGARGCNYTNTAY CCNGCN---------ACN---------GGNAARGAYCAYCCNGAYTTYCAYMGNYTNCAR TTYTTYAARCCNATHAAYATGMGNTCNYTNYTNATHAAYTAYGAYCCNAAYGARGTNTCN GAYYTNTGGAARCCNTAYGAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CARACNGGNTCNGGNAARACNYTN ACNATGYTNGGNCAYTCNGARAAYTCNGAYGGNTTYCARCAYGARYTNMGNGGNGTNATH CCNMGNAGYTTYGARTAYYTNTTYAGYYTNATHGCNCAYCARCARGAYATGCAYGGNAGY GARAARCARTTYYTNTGYMGNTGYTCNTTYYTNGARATHTAYCARGARCARATHTTYGAY YTNYTNGAYCCNGCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CCNGCNAGYGTNAAYCCNGTNTCNCCNMGN CARTTYYTNAAYACNCCNCCNYTNAGYCCNGAYCARGTNGTNCCNAGYCCNAAYCCNTAY TCNCCNTCNAGYCCNAAYGCNATHTAYTCNCARTCNCAYAAYTCNCCNAARTCNCCNAGY CCNCCNGTNAGYCCN---TTYCAYGTNGARTTYCARGTNACNGARCARGAYYTNCARYTN ACNTCNGTNCCNGAYTAYGAYTCNGAR---TAYCCNGAR------CCNGCNTGGMGNCCN AAYGGNAAYGGNMGNCCNCCNAAYGGNAAY---------AAYTTYGAYCCNMGNAARMGN AAYTTYTCNGARGARGARYTNAARCCNCARCCNATHATHAARAARTCNAARAARGTNTTY GTNCCNGARGAYYTNAARGAYGAYMGNTAYTGGGCNMGNMGNCAYAARAAYAAYTTYGCN GCNAARMGNTCNMGNGAYGCNMGNMGNGTNAARGARAAYCARATHGCNYTNMGNGCNGCN TAYYTNGARAARGARAAYACNTGYYTNAARGARGARATGATGAARYTNMGNAARGARAAY GTNAARYTNAARGARAARGTNTCNACNTAYGAR--------------------------- AAYMGNCARGCNTAYATGGAYGCNGTNYTNCARGAYCAYCARCARAGYATGTCNGCNYTN TCNYTNAGYMGNAAYTCNGAYGCNACNGAYGCNGTNMGNGARYTNGAYAARAARTTYATH CARCAYGAYAARGCNYTNMGNMGNATGGGNGTNGCNAARAAYGCNTCNCAYMGNAARGGN TCNGCNGGNGGNAARMGNTCNTCNAGYAAYCARGARACNCCNGAYYTNACNGGNYTNACN ATGYTNGARYTNGTNGGNGARACNCCNTCNAGYAARCAYTTYGTNCCNGCNAAYGGN--- ------CAYYTNACNAARCARYTNTCNGARGGNGCNYTNMGNAAYACNACNCCNTCNMGN GGNTAYMGNTAYCCNCCNAAYGCNTAYAAYGAYCCNAAYMGNTAYACNGARACNAGYYTN TAYGCNYTNMGNGARCARGAYGGNATGMGNAARCCNMGNCCNGTNAGYGCNTCNAGYYTN AARGAYGGNGAYAAYATHMGNGCNMGNCCNAARACNGCNGCNTAYGCNMGN--------- GAYAARCARACNTTYATHACNCARAAYAAYGARMGNTCNYTNAARTAYGARACNACNMGN CCNGTNCAYCARMGNTCNAAR------TCNGCNAARCAYMGNMGNGGNTCNGCNGARGGN CARYTNAAR------------------------CCNTCNYTNAGYCARAGYAGYYTNGCN TCNMGNTCNAAYAAYCAYGCNATGTCNAAYACNAAYYTNTCNGCNCCNTCNTCNTCNGAY MGNATHCARCARGAYAGYAAYACNAAYTCNGCNAAYGARYTNCCNCAR------------ ------GAYACNGAYGGNAAYGAYTCNGARTAYCARGARTCNGARTAYTTYGAYTCNAAR CCNCCNATHGCNATHMGNGTNAARTCNGCNTTYCARMGNMGNCCNGCNGCNATHGAYAAR TTYGCNGAYGAYGARAARGTNATGAARGARATGGARGCNGAYTTYMGNAARACNGCNYTN AGYYTNCARAARAARYTNGGNATHGARGAYCARGGNATGATHGAYATHGAYAARAARTAY YTNGARTCNGTNMGNCCNYTNGCNACNGAYGARGARTAYCARCAYACNGARMGNYTNGCN CARGARTTYGCNGCNGGNGAYGGNAARTAYYTNCARGARMGNYTNATHGARAARGCNAAR GGNCARMGNAAYTGGYTNGARAAYTGGTGGAAYGARATGGCNTAYYTNGARYTNMGNATG CCNYTNCCNTAYATHAAYATGGGNGCNCCNGGNCCNTAYGTNGARGGNYTNCAYCCNGCN CARCCNGGNACNCARATGCARMGNGCNTCNATGATHGCNCAYTAYACNATHACNYTNTGG GAYTAYYTNGTNAARGARMGNTAYAARCCNCARMGNGAYGGNYTNAARMGNCCNYTNTGY ATGYTNCARTTYCAYATGYTNTTYAAYTGYTGYMGNATHCCNGGNGTNAGYAARGAYTCN YTNGGNACNTAYTTYAARACNGARACNGARGGNGARGCNCCNAGYCAYATHGTNGTNCAY TGYAARGGNCAYCAYTTYYTNGTNAAYATHTTYAGYGARGGNGGNGAYATHYTNACNCCN YTNGARYTNGARYTNCARTTYAAYMGNATHAARGARMGNGCNCARAARYTNGGNACNTCN CARCAYGTNACNTAYYTNGCNTCNYTNCCNMGNACNGARTGGGCNCAYGCNMGNAAYMGN YTNATHGCNYTNCAYCCNAARAAYTTYAARACNATHGARMGNATHCARCARGCNATHTTY TGYATHGGNYTNGARGAYGGNGAYGCNACNGAYATGACNGAYYTNGCNACNAARTCNYTN ATGGGNCARYTNGAYAAYMGNTGGTGYGAYAARTCNTGYACNYTNGGNATHTAYGARAAY GGNYTNTCNYTNTAYGCNGCNGAYCAYACNCCNGCNGARGGNATHATGATHGTNTAYGTN GCNGAYTAYGTNTAYTCNAARATHAARCARTCNGGNGGNTTYTGGAARGGNTCNCARGAY GTNMGNCCNAAYCCNCARCCNGARATGYTNGARTTYGTNGTNGAYGAYGTNATHAARAGY GARGTNGTNMGNGCNAARAARYTNTAYAARGARYTNCARGARACNACNGAYGTNATHATH CAYATGCAYACNGCNTAYGGNAARMGNTTYYTNAARACNAARMGNATHCAYCCNGAYACN CAYTGYCARATGGCNTTYCARYTNGCNTAYTAYTCNYTNTAYGGNAARATGGCNCCNTCN TAYGARACNGCNGCNATHAARCARTTYTAYCAYGGNMGNACNGARACNATGMGNTCNTGY ACNATGGARGGNTAYGARTGGTGYAARAGYATGGTNAAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CAYAAYCARYTNGARAARAAYMGNMGNAARCARYTNMGNGARTGYTTYAAYCAYYTNCAR CARTGYGTNCCNTCNYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TGGCCNGAYGCNAGYAAYATHCARCCNATGACNGAYGCNCARGGNTCNTCNGAYYTNTGY CCNAARACNAARTAYGARCARMGNYTNATHTTY------ACNYTNACNTCNGARATGTGY ATGGTNMGNTGYAAYYTNATHGAYGARAGYAGYMGNYTNYTN---------GAYACNGAY AAYAARACNTTYCCNATHACNTCNGGNGGN------------------GGNAAYCCNGGN GCNGCNAGYGCNGGNACNGGNATGATHGTNGGNATHGTNGTNGCNGTNYTNATHGTNATH GTNGTNGTN---TGYATHYTNGTNTAYGTNTTYTGGTTYMGNAARMGN---GAYAARGGN AARGGNTAYAARTCNGAYGARCCNGAYAAYGCNGCNGARAGYAARTCNCCNCAYGCNCCN CCNCCNGTNTTYTAYTCNAARGGNGGNAARCCNGAYAARGARGAYCAYGAY--------- ------------------------------------------------------------ ---------------------------------MGNTTYTCNGCNAGYCCNCARGCNTAY GCNGTNGTNTCNAGYCCNAAYCAYGCNGGNTAYAGYCCNATHTCNCCNGCNTAY------ ---------TAYAGYGGNYTNTCNGCNATGACNTCNTCNAAYCCNGCNTAYATHTCNCCN GGNCARTAYCCNGCN---TTYAGYTAY---CARTCNGCNATGGCNCCNMGNACNYTNGCN ------------GGNCCNTAY---CCNGTNCARGCNGGNGCNCCNYTN---ATHGCNGGN TAYTCNACNATGGCNGGNACNATHCCNGGNCAR---CCNGCNMGNTCNTAYCCNGTNGGN GCNGTNGCNGCNTAYCCNGCNGGNTAYCCNYTNCCNACNCCNMGNACNGGNCCNATGCCN TAYCAYGGNACNGAYATHYTNTTYYTNCARACNGGNGGNACNATHGAYAARACNTAYCCN CARGARGTNGGNGCNTAYGGNTTYGARATHGGNTCNCCNGCNGTNGARAARATHYTNACN AARATHAAYCCNAGYTTYCARTAYMGNATHGARACNGTNTGYMGNAARGAYAGYCARGAY ATHGAYCAYGAYGAYMGNGARGAYYTNYTNMGNGCNGTNGTNGAYGCNAAYCARCARYTN ATHYTNATHACNCAYGGNACNGAYACNATGTGYGARACNGCNMGNTTYYTNGTNAARGCN GGNGTNGGNCARGGNYTNGGNTAYGGNCCNGGNGTNGGNGARAARATHGTNGTNATHACN GGNGCNTTYCARCCNGARTGYATGAARTCNTCNGAYGCNGARTTYAAYGTNGGNTTYGCN GCNGGNGTNYTNCARTCNTCNTCNTCNCCNGGNGTNYTNATHGCNATGAAYGGNGCNYTN YTNGAYGGNTCNCAYGCNGCNMGNAGYCARGAYGGNAAYTTYGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNACNGAYTAYGTNAGYACNCARTTYGTNATGAAYAARATHGAYYTNTTYAAR GAYTAYGAYGAYCCNACNAAYTTYTTYMGNCCNTCNGTNMGNTCNYTNYTNGTNATGCAY ATHYTNATHAAYATGAAYATH------GAYGAYGARAAR---------ATGGARGAYGAY GAYGAYGGNCARMGNACNACNTGYGCNTGYYTNCCNCARATHTGYMGNAAYGTNTTYTTY TAYGGNYTNCAYGARAGYGTNACNGARACNACNGTNTCNAAYTCNACNACNCCNTCNTCN GCNYTNAARGAYGTNYTNGGNGAYGTNAARAARGCNTTYGAYAAYAAYATHACNCCNTTY TAYGCNYTNTTYATHTGYGCNTGGGGNACNYTNTTYYTNGARGTNTGGAARMGNCAYMGN ATHACNYTNGCNTAYGARTGGGAYGTNGAYCARTTYGARTCNAAYGARCCNGAYMGNCCN CARTTYTAYGGNACNMGNACNAARACNGAYCCNGTNGTNTCNTTYTCNATHYTNATHYTN ATGGTNGCNYTNGTNYTNGTNAGYGTNGTNGCNATHATHYTNTAYMGNATHATHATGAGY ATHGAYTAYTGYCCNCARYTNGCNGAYAAYGARTGYTTYATGYTNACNACNYTNYTNTCN TCNGTNYTNAAYGGNYTNTCNATHYTNYTNYTNGGNAARYTNTAYGAYAARYTNGCNGTN ATGYTNACNGAYTGGGARAAYCAYMGNACNCARACNAARTAYGAYGAYGCNYTNATHATH AARYTNTTYGCNTTYCARTTYGTNAAYAGYTAYGCNTCNTGYTTYTAYATHGCNTTYTTY MGNGGNCARYTNTCNTTYCARGTNYTNGTNYTNATGGTNATHAARCCNGTNCCNAARTTY GCNAARGAYATHYTNATHCCNTTYGCNAARAARATHTGGCARATHGTNMGNCAYTGYMGN MGNTGYTGYAARGTNAARGARCARGAR------------GTNGAYATHGARGAYGGNAAR CAYCARGAYCAYATGGCNTAYYTNGARCAYGARMGNYTNAARCCNGAYYTNGGNGAYTTY ACNYTNGGNGARTAYACNGARAARGTNATHYTNTAYGGNTTYYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------YTNATGAARTAYGGNGAYATHTGYAARAARATHAARTCNAAYATHAARGGNAAY ATGAGYGCNTGGGARMGNGTNAARAARCARTCNAARCAYYTNGARAARGTNCARCARAAR YTNCCNCCNTCNAGYCCNCARGTNATHAARGCNCARGCNGAYGTNGTNYTNMGNGARTAY GTNCARATHGARYTNGTNTTYCAYGCNAARGCNGAYATGGAYCARTTYMGNACNGCNYTN YTNGARGCNTCNGGNYTNGCNMGNTCNTTYACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGYTNTCNMGNTCNGGNMGNGCNGARACNMGNAGYMGNGCNAARGAR GAYATHAARMGNGTNATHAAYGCNATHGAYAARGTNMGNAARTGGGARAARAARTGGGTN ACNATHGGNGAYACNTCNYTNACNGTNATGAARTGGGTNCCNGTNACNGCNCARGARAAY CCNGGNGCNYTNMGNAARATHCCNGGNGTNAARACNAARACNTAYTCNAARGCNMGNGTN GARMGNGARMGNGARYTNTTYGCNGCNGARACNAAYGGNYTNYTNMGNGCNACNTCNCCN AGYGAYTCN---------AAYACNAAYACNTCNAAYGCNAAYAGYCCNTCNTCNMGNAAY CAYGGNAGYAARAGY------------------------GCNGGNAARAAYGGNACNYTN GTNTAYACNGARGARAGYACNCARCARTCNGTNGGNTCNTAYGGNTCNGAYAAYYTNAAY GARGAYTCNAAYATGTCNTTYCCNGARCAYAGYGARCAYAGYGARCARGCNGAYCAYAAY GARTTYTCNCAYGAYAGYAAYGAYGCNGAYCCNGARATGMGNGTNGCNATGAGYATGGTN MGNGARGARGARAARGGNAGYGCNAARTCNCCNGARGARGCNACNGARTCNGGNCCNCCN GAYYTNGARMGNGAR------YTNCCNTCNCCNGARGCNAARAARGCNAARTCNGGNTCN ATGTCNGARAARCAYAGYTTYGGNATHGCNCCNGTNACNTGYCAYACNTTYAGYAARGAY MGNAAYGGNYTNGCNYTNTCNYTNAAYGAYTCNAAYGTNAARATHTAYAARAARAAYGGN GCNAARTGGCARGARACNGAYACNYTNAGYGARCAYGGNCARMGNGTNACNAGYATHGAY TGGGCNCCNGTNAGYAAYMGNATHGTNACNTGYTCNGCNGAYMGNAAYGCNTTYGTNTGG ATGYTNGARAAYGGNAARTGGAARNNNGTNYTNGTNATHCCNMGNATHAAYMGNGCNGCN ACNTGYGTNAARTGGTCNCCNAARGARAAYAARTTYGCNGTNGGNAGYGGNTCNMGNYTN ATHGCNATHTGYTAYTAYGAYGAYGARAAYAAYTGGTGGYTNAGYMGNCAYATHAARAAR CCNATHMGNTCNACNGTNACNTGYATHGAYTGGCAYCCNAAYAAYGTNYTNYTNGCNGCN GGNTCNACNGAYTTYAARTGYMGNGTNTTYTCNGGNTAYCARAARGARGTNGAYGARAAR CCNAGYCCNTGYTCNTGGGGNACNAARATGCCNTTYGGNAAYYTNATGGCNGARTTYAGY AAYGGNGGNGGNGGNTGGGTNCAYTCNGTNTCNTTYTCNGCNAGYGGNGAYMGNYTNGCN TGGGTNGGNCAYGAYTCNAGYGTNTCNGTNGTNGAYGCNGCNAAYGGNAAYCAYYTNTCN GTNGTNAARGAYACNTTYYTNCCNTTYATGGGNATHAGYTGGATHACNGARAAYAGYYTN GTNGCNGCNGGNTAYGAYTGYAAYCCNYTNYTNTTYTCNTTYGAYGGNAGYATHGTNACN YTNGGNGGNAARYTNGAYGTNCCNCARGARAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNGGNACNGTNAARATHACNACNAARAARGTNGAYTAYAAY GTNACNAGYMGNATHGGNTCNAARGAYAARATGACNCAYAARCCNGGNGGNGGNAAYGTN AARATHGARACNAARAARGTNCAYYTNTCNGTNAARTCNAARGTNGGNTCNYTNGAYAAY GCNAGYCAYAARCCNCARGGNGGNGAYAARAARATHGARGTNMGNAARACNGARTGGAAY GCNAARTCNAARGTNGGNTCNYTNGAYAAYGCNACNCAYGTNCCNGGNGGNGGNGAYAAR AARATHGARACNCARAARACNGAYTGGAARGTNGARGCNAARATHGGNTCNYTNAARAAY GTNAARCAYCARCCNGGNGGNGGNGAYAAR---TGYGCNYTNTGYCCNTGYCCNYTNYTN ACNGCNTAYTGGACNAAYCCNCCNTCNYTNCCNMGNMGNYTNYTNTGYGARAAYAARTGG YTNTCNTTYTGYTGYTGYTGYATHMGNGAYTCNGARACNGTNTGYATGTTYGTNGCNGCN YTNTTYYTNACNTAYTTYATHACNATGGAYYTNATHYTNTAYAAYTAYTTYAGYAARGCN GAYYTNGTNGTNGARTCNCARGGNGGNAARTCNACNGARATGTAYACNCCNTTYACNCAY YTNACNGTNAARGCNATHYTNAAYGAYCAYCCNAGYCARTTYATHATHGCNCCNAGYACN GARTAYTTYGARCAYTTYACNCAYTTYAGYCARCAYTTYCCNTGGATHACNCCNAAYATG ATHTCNTTYTCNCAYYTNATHTGYGGNTTYATHAGYGGNAARTTYGTNTCNTCNGAYAAY YTNTAYGAYMGNMGNATHGGNGTNATHYTNTTYGARATHMGNACNTGGYTNGAYGCNTTY GAYGGNACNATHTTYMGNGCNCARGCNGGNYTNCAYYTNAARTAYACNTCNTTYCAYAAY ACNYTNGGNTAYTAYATHGAYTCNGTNTTYGAYTCNYTNGGNGGNYTNTTYYTNTGYYTN GGNGTNTTYTTYTAYYTNGTNAARMGNTTY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNAARTTYATHGTNTTYGAYYTNGAYTAYACNYTNTGGCCN TTYTGGATHGAYCAYCAYYTNCARCCNCCNTTYAAYCARCCNTCNGAYGGNCCNGTNTTY GAYGAYTGYGGNGCNCCNGTNGARTAYTAYAAYGAYGTNCCNGCNATHYTNAARGARYTN TAYGAYGAYGGNGTNAARYTNGGNGTNGCNTCNMGNACNTCNGCNACNTCNGAYGCNAAY TCNYTNYTNAGYYTNTTYAARTGGGAYCARTAYTTYCAYTAYAARCARATHTAYCCNGGN TGYAARAARACNCAYTTYGARAARYTNCARGARGARAGYGGNATHCCNTAYGARGAYATG YTNTTYTTYGAYGAYGARCCNMGNAAYATHAARGAYGTNGARACNYTNGGNGTNACNTGY ACNYTNGTNACNGTN---GGNGTNGAYMGNCARACNYTNAARGGNGGNYTNCARCARTTY GCNMGNAAYCARAAYAARMGNAARACN------TCNGGNCAYGAYGGNGAYACNATHCCN AGYACNACNACNACNCCNGARAARAGYAARGCNAARATGGCNTGGGAYTTYGGNCAYTTY GGNYTNATGAAYGAYATHTCNYTNGAYACNMGNTCNAGYTCNGAYMGNYTNTCNMGNGAY AARCCNAAYTAYACNTCNGAYGGNGAYGARACNMGNACNTCNGGNAGYAGYGCNAARATG GARGAYCAYGCNGCNGCNGAYYTNGCNATHGCNGARATGTCNGGNCAYCARCAYCAYGGN TAYGGNAAYCARCARTCNACNTGYGAYGTNGAYCARATGATHACNAGYTTYMGNGAYCAR MGNAARGARYTNGARAAYMGNTAYCARACNYTNACNAAYCARGGNYTNGCNGARAARGTN TTYMGNATHYTNACNAAYCARGAYCCNGAYTCNCARGCNAAYGGNATHYTNTCNGARGTN AAYGCNGARGARMGNGARATGAARGCNMGNYTNGCNYTNAGYYTNCAYAAYAARGARTTY AAYTTYTCNTCNAAYTCNAGYCAYTTYGAYGAYTCNAAYAAYAGYYTNAAYYTNCCNGAY GAYGTNMGNAARMGNYTNGAYYTNTCNGCNYTNAGYTCNAARGAYTCNAGYCAYATHTTY GAYMGNYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CARTGGTGYTCNGCNGTNAAYTGY AGYAAYTCNMGNAAYAARMGNCCNGAYYTNGGNTTYTTYMGNTTYCCNYTNGAYCCNGCN MGNTGYMGNMGNTGGGTNATHAAYTGYMGNMGNGCNGAYYTNGAYGGNAARTCNGCNGTN GAYYTNAAYAARGCNAAYGTNYTNTGYCARGARCAYTTYGARCCNTGYTTYATHAARAAR TCNGARCAY------MGNACNMGNATHGTNAARGAYGCNGTNCCNACNYTNTTYAAYGTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CARYTNGGNGARGTNAARAARATGGTNATHCARGCNCAYGCNATH GARAARGARAAYGCNGARYTNAARAARGARAAYAGYTAYYTNAARTCNYTNYTNGCNAAR ACN------------------------------------GAYTTYCARCAYMGNTCNAGY AGYMGNTCNAAYATGAGYYTNYTNYTNTCNGCNTCNCCNAAYCARTCNATGMGNGTNTTY AARTGYGTNATHTGYGGNGAYGARYTNTTYACNGAYACNTAYAARTAYGARATHAARGAY GGNGTNGTNMGNATHGTNGCNCARCAYGTNACN---MGN---TCNGAYAARATHGAYGAY MGNGCNTTYGGNGGNAAYCCNAGYGCNGARGAYGGNGCNGAY---GARGCNGAYCCNAAY GCNATHTCNGGNGTNAAYGTNGTNYTNGAYTTYMGNYTNCARAARGCNCCNTTYAAYACN AARAARGAYTAYATGYTNTAYTTYAARGGNTAYYTNAARMGNYTNACNGCNAARYTNAAR GAR---AAYCCNGAYTTYGAYGARACNGCNTTYCARGARMGNACNAARACNGCNTTYGCN AARATGTCNAGYYTNTTYAARGCNGCNGARTTYTAYATHGGNGCNTCNGARGAYGARGAY GGNGCNATGGTNGCNTGYGTNTGG------GARGAYATHGAYGGN------GAYCARGTN CCNGTNATGTAYTTYTTYTAYGAYGGNYTNGTNTCNGARAAR---GCNATGGGNTCNMGN AGYCARAGYGARYTNYTNGAYATHYTNGAYCARTAYAARCARGGNACNTTYAAYATGGAY GAYGCNGARATGYTNTTYMGNGCNTGGAARAGYMGNTAYGGNACNGGNCARGGNCAR--- AGYTTYAARGCNAARATGAARGAYYTNAAYGARTTYMGNACNATG--------------- ------------------------------------------------------------ ------------------------ACNTCNGAYCCNATHTCNATHAAYTGYATGCCNGTN TGYAAYGCNGARTAYYTNYTNGCNGARCARTGYGARATHGCNGCNGGNTGYGAYGTNAAY ACNCARACNAAY------GARGARTAYAGYGCNTGYTCNMGNCCNTGYTAYGCNCARGCN TCNAGYTGYTAYATHTTYTGYMGNGAYAAYTTYGAYGCNGTNTAYGAYGCNTGYGAYGCN AARTGYGCNMGNMGNAARMGNYTNGGNTGYTCNAGYYTNTGYTTYTTYAARAAR------ ---------CCNCCNMGNAAYAAYMGNGTNTGYGAYGGNTAYGARAGYTCNGARGARGAY GGNAARGAYGCNGAYMGNAAYGCNTCNGAYGARGAYACNGCNGAYGCNAGYGARACNGAR GARAARCCN---AARTCNAAYAAYCARAAYGCNACNAAY---TGYGGNCARMGNACNGAR ATHAARGARCARATGTAYCARGAYAARYTNGCNCARATHAARAARCAYATHGGNCARYTN CARGARGGNTCNYTNCCNGARTTYYTNAARMGNACNMGNAARATHGARYTNAAYTAYMGN GAYMGNYTNMGNTAYAAYGARATHTGYAARATHATHGAYATHGARAARGTNAAYCARAAY TAYCARATHGAYTGYGARAAYTCNCARAARGARTTYGARGARAARCARGARGCNYTNAAR GARACNYTNYTNTCNCAYYTNAARGAYAARAARGTNGAYYTNAARGARACNYTNATGAGY GAYYTNMGNGARAARMGNAAYATGATHGARYTNGARTGYYTNACNACNGAYYTNAAYGGN GCNGAYTTYATGGARGTNAARCCNACNATGACNMGNAARYTNMGNMGNMGNCCNAAYGAY CCNATGCCNATHCCNGARAARMGNMGNAARCCNTCNCCNGCNCARGTNAAYYTNYTNYTN GAYGAYGAYCARATHYTNGCNGAYYTNMGNATHATGATGAARGTNAGYGGNAARCCNGTN GCNAARAARCARGCNYTNTCNCARCAYAAYCCNYTNYTNGAYTCNTCNTCNGAYGTNMGN ATHGARGAYGGNMGNYTNTGGTAYGAYAARAARTGGTTYCARMGNAAYAGYATGGTNCAR ATHGAYAAYAARGARGGNGGNCCNMGNATHTAYGGNACNATHACNAAYATGGGNAAYCAR GARATHTGGATHAARMGNAGYGGNGAYAAYTCNAARYTNMGNATHTTYYTNTCNCARTTY CARAARGGNAARTAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTCNMGNGCNGCNCCNTCNAARACN MGNGGNGCNGAYAARACNAARCCNCCNGCNGCNCARACNCCNGTNATHGCNCAYGARATH GTNCCNGGNAARTTYAAYGARAAYGAYTGGAAYTCNATGYTNGAYAARGAYGGNTCNGAY GARTTYGTNATGGAYATHATGGAYGARYTNATGGARAARACNATGTCNGCNATHTAYGAY AARTAYATHCARMGNCARYTNYTNCCNTTYACNATHACNCARGCNMGNGAYGCNATHGTN GARATHATHGARTGGCARTTYYTNGCNMGNGAYGARGGNGARACNACNGTNGCNGAYGAY ATHGGNTGGACNCARGAYGARGARCCNGARCCNGCNGARACNGAYTGYTGGGCNCARGGN TCNGTNCCNAARAAYTTYATHGCNGCNCCNACNCCN------------YTNGARGARATH AARGAR---------GARACNGARGARATHAAYGARGARGTNGGNGARCARGARACNGAR GARAARGCNGCNAARGARCCNGARGARYTNGCNGAYGTNGTNTCNGAYACNGARGARTCN CARGARCARGTNGTNAARGARGAR------GCNAARAARAAYAARTCNGARATGATGACN AGYAARAGYTCNACNAARTCNTCNAARTCNAAYTTYAARCCNTAYMGNGGNAARYTNAAR TCNGCNGGNGTNAGYMGNATGACNGARACNYTNGARGAYTCNGARATGAARATHTGGTAY GAYGARYTNAARGARTGYATGCCNCCNGCNGARGAYAARCCNAAYACNYTNYTNAAYATG CCNGCNTCNTGYACNAGYATHYTNAARGTNCARACNGGNMGNCCNCCNGGNAAYAARGAY GTNGTNTAYGAYGAYTTYGGNAAYGTNGTNACNGTNATGMGNYTNGAYCCNGARAARYTN CCNACNCAYAARGTNAAYGTNAARTAYCAYGTNGTNGAYCCNGCNGTNGARGCNGCNCAR GCNMGNYTNGAYGCNATGMGNAARGGNAARTCNACNGGNAGYAARATGMGNAARGCNMGN TCNATHAARAGYYTNTCNAGYGARTCNCARGCNACNAGYTCNAARYTNAARTAYACNCAY AGYACNGGNTCNGTNGCNCCNYTNCCNCCNCCNYTNYTNAARGAYCARGCNTCNCARTCN AAYGTNATGACNTCNCARAARCARGTN------ATHGARGARATGGARGTNTCNCAYGGN GTNGTNATHMGNGARGGNGGNMGNGTNAARAARGGNCCNGGNMGNTAYTAYMGNAARYTN GAYATHYTNGARGARAAYCARAARGGNATGATGCCNGTNAGYGTNMGNYTNAGYACNGCN GGNATHACNGTNGGNGAYYTNYTNGAYMGNCAYACNCCNATHYTNMGNCCNYTNGCNGAY ACNTCNCCNYTNCCNCCNATHGTNCCNCAYCCNCCNAARCARTCNCAR---CAYGTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GTNTCNGGNACNGTNGTNTAYAAY ACNCCNCARGAYMGNCARTAYGCNCCNATHMGNGAYYTNGTNMGNGAYTTYCAYGCNYTN ---TCNGARGARGARYTNAARMGNCARGGNYTNAGYGAYTAYAARTAYGGNTAYTTYTTY ACNACNATHATHGCNACNACNCCNGTNTAYYTNGARTGGYTNATGAAYMGNTTYATHGGN GCNGGNGGNAARGTNCARMGNMGNCAYGTNGARGAYYTNAGYGARYTNGTNGGNGARTTY GAYYTNGTNGTNAAYTGYTCNGGNYTNATGGCNAARACNYTNATHAAYGAYAARCARATH TAYCCNGTNAARGGNCARYTNGTNATGGTNAARGCNCCNTGGGTNAARAAYTTYTTYTTY AGYGAYGAYCAYATHTAYTTYATHCCNCARATGGARMGNYTNGTNATHGGNGGNACNMGN GARAARGAYTTYGTNACNGAYGGNATHCARCCNGARACNTCNGCNMGNATHYTNCARMGN GCNCARAARYTNTTYCCNCARYTNAARGGNGCNGARAARYTNTCNGARTGGGTNGGNTTY MGNCCNACNMGNGARCCNGTNMGNGTNGARTAYGARYTNTTYGAYAGYGGNCCNAARGGN AARYTNCARGTNGTNCAYAAYTAYGGNCAYGGNGGNCAYGGNATHACNYTNAGYTGGGGN TGYGGNAARCAYGCNGCNMGNYTNGTNCARAAYGCNYTN---ATGGCNGAYGAY------ ------CCNGCNTCNCCNCCNYTNCCNAARMGNGGNGGNTAYAAYATHGAYTTYGAYGCN YTNGAYGAYATG---AAYCCNTTYGCNTCNMGNAGY------AGYYTNGGNTCNTCNCCN CCN------------AARTCNAGYGAYGARCCNGTNTCNCARGAYGCNATHAARGAY--- ---------------------GCNTCNAGY------------------------GARCAY AAYAAY---------CARTTYGAYGARCCNAGYGAYYTNTCNGTNTCNTCNGTNCCNAGY ACNCCNGGNTCNACNAAYATHCARATHGARACNTCNCCNCARGGNGGNTCNGGNAAR--- ---GTNATHCCNAARAARAARAARATGATHAARMGNCCNAARGTNCARTCNAARTTYAAR CCNCCNAGYAAYGTNGARTTYCCNGARGAYAAYGGNGARGTNCARATHTTYATGCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGGMGNATH GTNAAYTGYATGATGGCNCCNTTYTTYTTYYTNGCNGCNYTNGCNAAYGCNAAYGAYTTY GAYTGGTAYGTNTGGATGCCNYTNTAYATHATHCCNGGNYTNYTNTGYYTNGCNGCNAGY GTNCAYCCNACNAGYGTNGGNCAYGGNTGGTGGMGNAAYYTNAAYYTNYTNGARTTYYTN YTNTGYYTNATHTAYGGNGTNTAYCAYATHAAYTCNTCNYTNAGYAARYTNYTNGGNGGN MGNCARAAYCCNYTNATHCAYGARGARGGNMGNGARYTNGGNGGNATGTTYATHATHYTN GCNTGGACNGGNATGGCNMGNTGGACNCCNAGYGARATGAGYAARAARGCNACNAAYCAR AGYYTNATGAAYYTNYTNYTNTGYATGGCNGTNACNYTNTCNATHATHCCNYTNYTNGCN TGGTCNYTNTGYTTYGTNAGYGAYTGGCAYAARCAYATHGGNCAYTGYAGYGGNATGTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR MGNGAYCAYACNTGYGAYGTNTCNGGNAARGARTTYATHATGTCNAAYCAYYTNCAYAAR CAYMGN------CAYACNGGNGARMGNYTNTAYAARTGYGAYATGTAYGGNAARMGNTTY ATHYTNCCNAGYCAYYTNCAYACNCARCAYGCNATHCAYACNGGNGARMGNCARTAYAAR TGYGAYGTNTGYGGNAARGGNTTYAGYGTNATHMGNACNYTNGTNGCNCAYAARYTNACN CAYYTNGCNGARCARCCNTAYACNTGYGAYATHTGYGGNAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ACNGTNAAYTTYYTNAARGGNTGYTTY CCNTCNAARTCNATHGAYCAYATHMGNCARGTNYTNGCNGCNAAYAAYGGNGAYGCNGAY AARGCNTCNATHGCNYTNACNAAYGARGCNCARTCNYTNATHCARAARCCN--------- ---ACNGTNCARCCNTCNAAYGGNGCNGGNAAYGTNACNATGAARCARAARATHAARAAY CAY------AARGCNAARMGNAARGARGTNGAYATGAGYGAYGAYGARGAYGARTAYGGN GAYGAYTAYGARAGYGGNGAYAGYGARGAYAGYGARGAYTGGGAYAAYMGNACNAARTCN GAYACNGAYAAYTTYYTNCARTTYTTYGARGARGCNAGYATHGARGARYTNACNGCNATG CCNGGNTGYTCNAARAARAARGCNGARATHATHATGAGYYTNMGNCCNTTYGARTCNTGG GAYGCNYTNTGYGARAARTTYGARATGGARAARACNYTNTCNACNTCNATHATHTCNGGN TGYAARGARATHATGCARGTNMGNAAYACNGTNMGNMGNYTNATGGTNMGNTGYGARAAY ATHTCNGARCARATGGGNAARGTNGTNTCNCARYTNACNGCNGGNAARACNTCNAGYAAY GAYACNGARACNGCNCARATHACNAARCARCCNGCNYTNYTNACNGARGARTTYAARYTN CARCCNTAYCARYTNATHGGNYTNAGYTGGYTNMGNYTNATGCAYGARCARGARYTNAAY GGNATHYTNGCNGAYGARATGGGNYTNGGNAARACNATHCARGCNATHGCNTTYYTNGCN CAYYTNATGGARGARGGNGARGARGGNCCNCAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARACNTCNAARAARTGYTTYTCNGCNGTNTCNYTNTAYGGN TTYAAYMGNATHTAYMGNTCNAAYGAYAARAARGAYAARGAYACNGTNTGGTCNTTYAAR ATGGARCAYATHCARCCNACNGTNGGNAAYYTNCAYTTYTCNTGYTCNTCNGARCCNGAY ATGATHAARTGGATGAARATHATHAARCARGARATGYTNATHGCNAAYGAYAARATHTCN ---MGNAAYYTNGTNMGNCARTCNGAYCAYYTNTCNCARGAYTCNYTNGAYTCNTGGGGN TCNTCNGAYTAYAGYGCNYTNGARTCNAGYATH---TAYGARTTYTCNCCNCCNMGNCCN GAYTCNGTNTAYTTYGAYGCNGTNGARGAYCCNGARATGGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GGNATHGCNMGNGAYGGNACNATGCARGTNACNGCNAARGARGGNATHGAYTAY YTNAARACNGARGGNAARACNMGNYTNYTNAARGARCAR---NNNNNNGAYNNN------ ------------------------------------------------------------ ------------------------------------------------AARNNNNNNYTN NNNMGNGAYGGNACNATGNNNNNNACNGCNAARGARGCNGAYMGNYTNYTNGGNGGNAGY AARCCNGAYGCNGAYGCNCARACNMGNGGNCARCARAARCARATHGAYGAYYTNAARAAR GARAARCCNGARCCNGCNACNAARAARGCNMGNYTNTCNAARGAYACNACNATGGCNGCN ACNGCNAARGARGCNAARTCNYTNYTNGCNGGNGARAARYTNGGNGAYACNMGNCARGAR ACNTCNAAYAAR------AARGCNAARACNCCNYTNAARAARGGNATHACNATGGCNAAR ACNGTNGARGARGCNAARTAYGTNYTNGAYGGNGARYTNGAYYTNTCNGARGGNMGNAAR ACNMGNTCNCARAGYMGNGGNGGNGARAGYMGNCCNGCNGTNAARMGNGCNGGNACNATG CARCARACNGCNAARGAYGGNAARACNTTYYTNAAYMGNGGNAAR---GGNAARAARGCN GCNACNGCNGCNGARGARGARGARGARGARYTNGAYGAYTAYGARYTNATHGAYTTYGGN AGYYTNTCNGARGARGARAGYAGYTGGYTNCAYAARGAYAAYGARCARGAYTCNGAYTTY ACNTCN---GARTTYYTNGARTCNTGGTGYMGNCARTTYTTYGAYGARMGNAAYCCNATH ATHAAYTCNGTNMGNATGGAYYTNAGYMGNAARATHGAYGARYTNTCNMGN------MGN TCNAAYMGNTCNGCNTTYGAYTCNGGNACNTTYACNMGNCCNAARMGNTTYGCN------ ------CCNATGCAYGGNGARGGNGAYCARGTNCARAGYGTNCCNGAYGCNGAYGARATH CARCAYYTNGCNAARCARCARGARGARAGYYTNMGNCARAGYATGMGNCCNTCNMGNAAY GCNATGMGNGCNAARCARGTNATGGTNGAYGGNGAYAGY---GCNMGNYTNAGYCCNAGY MGNTTYGAYGCNGAYGGNGCNTAYTTYAAYCARCAYMGNGGNAGY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TCNGCNGCNMGNACN ATG------------AARGTNGTNAARTCNCAYATHCCNYTNATHAARTTYCCNGCNMGN AARCCNYTNGARTCNTCNAAYTCNATHACNGCNAARGGNACNYTNCARTCNACNGGNAGY ACNGCNTCNTCNAGYGTNCARCCNTCNGCNAGYAAYGTNAGYTCNGTNAARACNAARACN GCNCCNGGNYTNTCNATHGAYTAYTCNYTNYTNCCNATGMGNTAYCARMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GCNCAYACNGARGTNGTNACNGAYGAYGAR GAYGGNYTNCARCAYTAYGGNCAYACN------GARCAYAARAARAARMGNGGNYTNMGN MGNYTNTTYGGNMGNYTNAARMGNAGYAGYTCNCARGAYYTNGARGGNGGNMGNGARAAR ------GGNGARGGNGARTTYAARMGNGGNGGNGTNMGNGCNACNGCNTCNGCNMGNYTN GCNTGGAAYMGNGAYATGAARGGNMGNATHTCNAAYACNGAYATHCCNTTYGCNMGNTGG GAYACNGARMGNATHACNGCNTGGATGAAYGAYATHGGNYTNAAYATGTAYYTNGTNGAY TGYAARMGNTGGGTNMGNAAYGGNGARCAYYTNYTNMGNAGYTCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYCAYACNCARTCNAGYCCNYTNYTNTTY AARGCNACNCARAAYYTNTGGGGNGARCCNATGAARAARMGNAARMGNGTNGAYCCNGGN YTNGARGCNTCNMGNCARCARAARAARYTNAARMGNATHGAYAARGARATHAARMGNYTN GTNMGNTTYGGNMGNAAYYTNAARCCNGTNGCNGARATHGARGGNAAYMGNMGNAARYTN ATGGCNGAYGGNTTYMGNMGNMGNGARCCNGCNGTNYTNTCNTTYGARGARAGYGARGCN MGNGCNGTNYTNCAYAARCAYTGGTCNMGNTAYMGNACN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYTCNGTNGAYTCNYTNTGGAAYATHGAYATGGAR GTNAAYYTNTTYCAYGCNATGMGNGGNCAYAARCCNGCNGGNGTNAAYMGNCAYTTYCAR ATGATHGCNATHCAYGARAARYTNAGYTCNTCNGCNAARAARATHACNTCNGGNGAYGTN TGGAARCAYYTNTCNACNYTNTAYGAYYTNCARGCNYTNAAYGARTCNGARATHGTNCCN TTYCCNAAYAARACNGCNGAYTTYGCNTTYTCNGARGCNGARGTNGCNGAYYTNTAYGAR AARACNTTYCCNMGNAGYTCNTAYATHAGYACN---GTNGTNGARGAYGCNACNAARCAR GARGAYAARTCNAARAGYACNTCNAARTCN---AARCARGARTCNAARTCNTCNGCNYTN ACNCCNAARGCNGARGTNAARTCNCAYAGYAGYAGYAARTCNTCNTCNAGYAARGCNGAY AARTGGGCNGTNTCNTCNACNCCNMGNGGNGAYAARTCNTCNAAYCAY------------ ------------AGYAGYGCNTCNAGYTCNTCNTCNCAYGCNTCNTCNTCNAGYTCNTCN AGYMGNTCNCCNAARMGNACNAARMGNACNMGNACNGGNAAYTCNAGYAAYACNAGYCCN GCNACNCCNACNGARCCNCARAGYAARMGNMGNMGNATGCARGARCARTAYTGYGGNACN CCNTCNTAYATGGCNCCNGARATGAAYTCNACNTAYTCNTAYCCNGTNGAYGTNTGGGCN ATGGGNATHATHATGTAYTAYYTNYTNACNAGYTAYCCNAARGAYGGNATHYTNAAYGAR TCNATHGGNMGNCARGGNCCNACNTTYGARGARCCNCARTGGAARGARGTNAGYGARYTN GCNAARGAYYTNYTNAARGARATGYTNAARAARGAYCCNGCNCAYMGNACNACNTCNGGN GARGTNYTNAAYCAYGARTGGTTYACNGGNAARAARAARGARTAYGGNAAYGTNYTNGAR YTNYTNMGNGAYTTYAAYMGNAARCCNAGYGTNTCNGAYGGNAGYGARCARGGNAAYGGN GAYGGNGAYGARAARGGNGAYAARGTNCARAGYGCNATGAAYGGNGTNAGYCAYATHGAY CCNGAYTCNAAYCARTCNAARAARGAYACNMGNATHGGNTCNGCNGGNAARAARTCNGAR ACNGGNCCNGGNGCNMGNACNCCNYTNAARGTNAGYGGNGCNAGYTCNCAYATGYTNMGN YTNTTYMGNGTNTTYMGNGTNTTYMGNYTNGTNCARCAYGTNCCNGGNYTNTGGATHYTN TTYTAYACNYTNAARGCNAGYATHAARGAYYTNYTNYTNYTNYTNYTNTTYYTNTGYGTN GGNATGYTNGTNTTYGCNACNYTNGTNTTYTAYGCNGARAARGAYGARCARGCNGARTTY TCNAGYATHCCNATGTGYTTYTGGTGGGCNGTNATHACNATGACNACNGTNGGNTAYGGN GAYATGTCNCCNACNACNAAYTGGGGNTAYYTNGTNGGNGGNATHACNGCNGTNAGYGGN GTNYTNATGATHGGNTTYACNGTNCCNGTNYTNGTNAAYAAYTTYGTNYTNTAYTAYAAY CAYACNCARTCNGCNYTNGARMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNMGNMGNGCNGAYMGNGARMGNAARGARCARCARGARAAYACN GTNACNAARYTNAARAAYYTNGARGTNGARTAYGARCARGTNAARAAYAARYTNGAYGCN TCNAARACNMGNAGYAARGTNYTNTCNAAYGARATHAARGGNYTNAARGCNGARGTNCAR ACNYTNYTNAGYAARAGYCAYAAYGAYGAYGARTTYATHGARGCNYTNATGAARCARCAR AGYAARYTNAARGARATGYTNGAYYTNAAYAGYACNCARCARGCNGARCARTCNCAYCAR TCNMGNCARAARYTNCARGARATGAGYATHAARAGYCARCARGAYAAYAAYGTNGTNGAR CARYTNAARTCNATHGCNGCNCARAARGARGCNCARGTNAARATGYTNGARATGGARYTN CARCAYYTNAARGCNGTNAAYCAYGGNAAYCARAGY---------------------AGY ATGCARGCNTTYCARAAYAAYGAYAGYCARTCNTCNCCNACNYTNGAYAAYGAYATGTCN ACNYTNMGNTCNMGNCCNGCNAGYCARMGNAGY------------------------ACN AGYTCNMGNCCNATHAGYMGNTCNACNGTNGTNYTNGARGCNCCNMGNGARAAYTCNGAR ATHGTNATGAAYCARGTNTCNATHAARGARAARGARAAYYTNGTNTCNCARATHCARGAR YTNACNGTNATHATGAARACNACNGARGTNGARAARGAYAARATGACNGAYYTNGTNAAR GTNYTNCARAARMGNYTNACNGAYGARATHGARAARCAYGGNGAYACNMGNACNGAYYTN CARGTNCARAARMGNACNYTNGTNGARATGGARAARCARATHGGNMGNCARGCNATGGAR GCNAARAARYTNGGNAGYGCNAARGGNAAYMGNACNAGYMGNGAYYTNGARATGGARGAY CCNGAYTCNYTNGAYGAYTGYAAYAARCARGARYTNYTNACNMGNYTNGARATHCARAAR GAYGARACNGARGCNATGMGNGCNGCNYTNCARAARACNYTNAARGCNAARGARGARGAY YTNAARGTNTAYAGYCARACNYTNGARGARACNAARATGGTNTTY--------------- ------------GGNGTNAAYYTNGTNCARTTYTTYAARACNACNYTNAAYAARTCNGCN AARGAYMGNAARTTYYTNYTNAGYYTNGARAARGARTTYTAYTCNTTYATHACNAAYACN ATGCARCAYACNCARAARYTNATGGARATGAAYCCNTAYGAYMGNATGGTNGCNCAYMGN ATGGCNGCNTAYCAYGGNYTNGARCAYAAYGTNGAYCARTCNGGNAARTGYATHGTNYTN ACNAARACNAAYMGNACNMGNATGCCNGGNAARAARATHGCNGAYYTNTTYGARCAYTCN GARTCNGGNGGNCCNCCNAARMGNAARATHYTNYTNAARAARCCNGCNAGYYTNGAYGAR AARCARAGYTGGAAYAGYAGYAARGCNCARTTYGGNTCNAAYMGNGCNAARTCNYTNGAR GARMGNCARCARAAYTAYACNGARGTNMGNGARMGNATHTTYAARGGNGCNGAYGGNATG GCNGCNCCNCAYCARYTNTGYCAYTTYATHCCNCARMGNAGYYTNGAYTGYGCNAGYYTN TCNYTNGAYTAYTCNAAYTCNTTYTGYYTNCCNGTNAARGTNYTNCARGARCARAAYGAR TTYMGNGTNCAYGCNGGNTGGATHACNTTYGTNTTYTTYYTNGGNYTNATHYTNGGNATH GGNATHGTNYTNYTNYTNGCNAARGCNTTYATGGGNGCNTGGCARAARAARAARMGNCAR GARGARAAYYTNATGYTNGARAARTCNGAYGCNCAYGTNGTNGARGCNCARCCNAARCAR TCNTGGGGNTTYCCNGGNMGNAARAARAARAARAGYYTNYTN---CCNGARAARGAYAAR ACNGTNGTNGTNCAYAAR---TCNMGNTTYTGGMGNAARGGNAARGTNAGYAAYAARGAY TCNGARGGNGCNACNGARMGNGAYGTNGAYCCNGCNTTYGCNMGNGGNATGATHGAYGTN YTNGTNCARACNAAYGGNTCNYTNGARAAYGTNGARATGGCNGAYCARGAYATHGCNAGY YTNATHTCNATGGARMGNGGNATHCARGARGARAARAAYACNATGYTNYTNAARGTNYTN TCNYTNYTNYTNGTNAARAARATGGARAARAARACNATHACNCARAARTTYYTNGTNAAY TTYAARYTNMGNATHGAYGARGAYYTNAARGAYATGGARAARATGATHGAYMGNGARAAR GARGARGCNGARGARAARYTNAARAGYGAYCCNAARYTNAGYAARGAYAGYCARACNYTN GARACNGARATGCARAARYTNCARACNTTYTAYAAYAAYAARCARGCNAARTGYCARMGN GAYTTYMGNGAYAARATHMGNYTNGARYTNYTNMGNTCNTCNGGNATGACNGAYGCNGAR GTNGAYGARATGATGGCNAARYTNATGAARAGYATGGCNGTNGTNGARGARAARATHGGN YTNGARCARGCNMGNCARMGNMGNAAYYTNGARGARMGNYTNGCNAARMGNMGNCARGCN YTNGARTAYAARGARYTNGARGARCARGGNGARAAYAGYGARAGYAARGARMGNGTNATH GCNTTYGGNGARYTNYTNAAYGTNCAY---GARAGYGGNGARGCNYTNGARAARGTNMGN GAYGARYTNGTNACNGARTAYGGNAAYGAYYTNAAYYTNATHAARAARTAYCAYGGNACN GARTTYAAYCARYTNCAYYTNGARAARGTNGARGAYYTNCARAARAAYMGNGTNGARGAR TTYCAYAARYTNAAYAARAARCAYGARAARGARAARAAYTCNTTYYTNCARACNGGNAAY AARAAYAGY---CCNYTNGAYYTNGTNAARYTNTAYCAYGAYYTNATGACNAARCARCAY ATGGARCARGARGCNYTNTGYGGNGAYYTNGAYCARYTNGARGTNCARGARATGCAYAAY YTNAARCARGGNATHTCNAARCARGARMGNAARGAYATGAAYAARAARACNGAYGARYTN GTNGARAARYTNGARAAYMGNACNAAYATGACNYTNTCNGARGCNGARMGNYTNATHAAR YTNCAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GTNCARTTYAAYCARACNGGNCCNATHAARGTNMGNGCNGGN GCNGARAAYATHAAYATGGARTGYACNGTNAAYMGNGGNGTNATGTAYYTNYTNAARAAY AARGCNGTNATHGTN------------CAYAAR---------AAYGCNGARGGNAARGAR ACNGARATGTCNTCNGGNGGNACNYTNGARAAYGCNCCNCCNAGYTTYTAYAARGTN--- ---GAYGTNCAYATGATHGGNTCNGAYGARATGMGNGTNGAYTTYAARATHYTNACNGTN MGNCCNGARGAYGAYGGNACNTTYTTYTGYMGNACNGCNGGNGGNGTNGTNTCNGCNGAR GCN------------------GTNGARGTNGTNGTNGTNAARAAYTTYGCNACNYTNAAR YTNAARTTYGGNAAYGARGARCCNATHACNAARAGYATHGARGAY------------CCN YTNGARATHGAYACNGGNAARTAYAAYGTNATGTGYACNGCNGARGGNAGYAAYCCNGGN TCNCCNAAYGTNGGNATHTTYATGGAYGGNAARCAYATHYTNTCNTCNAARCCNAAYATG ACNGARATGACNCCNGTNAARCARMGNYTNTTYCARACNTCNATHTCNAGYAGYATHGAY GTNGTNYTNGCNACNTCNGGNAARAARGTNGARTGYMGNGCNCARTCNCCNGGNGAYGGN GGNAGYCARYTNACNGTNTCNYTNCCNYTNAGYGTNAAYATHTAYGARCCNGARGTNAAR TGYAAYGARACNATHGCNTAYGTNGGNGARGARGCNCCNGTNYTNACNTGYATGGTNAAY CAYAGYGCNATHTCNGTNATHAGYTAYAARTTYCARATHGGNCARAGYGGNGARATHATH GARGAYAAY---------------TCNACNGAYGCNGCNACNATHAARACNGARAARYTN TCNGAYGARYTNGTNATGGTNACNYTNATHYTNTCNAARTCNGARAGYCAYCAYTTYGAY GAYCAYATHTAYYTNYTNATHGARAAYTCNGAYGGNCAYGTNACNAARACNMGNGTNGAY YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AAYGGNGARATGMGNMGN MGNAGYAGYCARACNTCNTCNAAYCARAGYGAYYTNCCNTTYGCNGTNATHAAYMGNAAY GTNATGMGNMGNGAYTCNTTYGARATGCCNCARMGNACNATHATHGAYTCNCCNMGNCCN ACNMGNTCNMGNTCNYTNCAYAARACNGCNAGYGAYAGYAAYGTNCCNGCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNGGNAAYGARCCNAAYTCNTTYCAY CAYGTNTTYAAYATHACNATHCCNCCNGARGCNYTNGTNAARGAYTTYCARATHYTNMGN GGNGTNYTNGAYACNTAYCCNCARTAYAARGAYAGYYTNYTNTAYGGNCCNGAYGTNACN AAYYTNGAYMGNCAYTCNTCNTCNMGNGTNTAYYTNAARGGNTTYYTNGAYGCNGGNGGN AGYAARGTNGTNGAYCARGTNTCNYTNCAYCAYTAYTAYYTNAAYGGNMGNACNGCNACN TGGAARGAYTTYGTNAAYCCNGTNGTNYTNGAYAGYYTNMGNAARGARTTYGAYATHGCN GCNAAYYTNACN------MGNCCNGTNAGYYTNACNGARACNTCNTCNTGYTAYGGNGGN GGNGCNCCNGGNYTNTCNGAYGGNTTYGTNGCNGGNTTYYTNTGGYTNGAYAARYTNGGN YTNGCNGCNCARTAYGGNATHCAYCARGTNTTYMGNCARACNTTYTAYGGNGGNCAYTAY TCNYTNYTNGAYAARYTNYTNAAYCCNAAYCCNGAYTAYTTYYTNTCNYTNYTNTTYAAR MGNYTNGTNGARGGNCCNGTNTTYGCNGTNACNGTNTCNCCNGAYGAYMGNYTNGTNMGN GTNTAYGCNCAYTGYGCNMGNAAR------YTNAARTAYAARGCNGGNGCNYTNACNYTN TAYTAYYTNAAYYTNMGNGAYACNGARCARACNYTNGCNYTNMGNCARTTYGCNAAYTCN TCNTAYGAYYTNTAYATHYTNACNAGYGGNGAYAGYCCNAGYGTNATHTCNMGNAARGTN GARYTNAAYGGNAAYATHYTNCARATGTCNGGNTCNACNYTNCCNGAYYTNAAYCCNGTN AARGGNAARGGNGTNATHGCNGTNCCNGCNTAYTCNTTYGGNTTYATHGTNGTNCCNGAY GCNAAYATHTCNYTNTGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CAYACNGGNGARAARCCNTAYAAYTGYGAYATHTGYGAYAARGGNTTYMGNMGNAAR GARTAYYTNMGNATHCAYGARGTNMGNCAYACNGGNGARAARCCNTTYAARTGYGAYGTN TGYAAYAARGARTTYMGNACNTCNGCNMGNYTNGGNGARCAYAARACNACNCAYTCNGTN GARMGNCCNTTYAARTGYCAYGTNTGYGGNMGNGGNTTYGTNTGYYTNAARTAYYTNACN AARCAYMGNAGYGTNCAYACNGGNGARAARCCNTAYAAYTGYGAYATHTGYGAYAARGGN TTYMGNMGNAARGARTAYYTNMGNATHCAYGARGTNMGNCAY------GARGAYGARGAY GAYATHGAYGARTTYACNCARGARGARATHGARAAYGARCCNGARAARCARATHYTNTGG GCNGCNGARAAYAAYAARATHGARATHGTNAARGARYTNATGGCNACNGAYCCNGAYYTN GTNTCNTCNCAYGAYAGYGAYTTYTAYACNCCNYTNCAYMGNGCNTCNTAYAAYAAYAAY GCNGARGTNGCNGARGTNYTNATHAAYCAYGGNGCNAARGTNACNGCNMGNACNATHGAY GGNTGGCARCCNYTNCAYAGYGCNTCNAARTGGAAYTCNGTNGARACNGCNCARYTNYTN ATHCAYTGYGGNGCNGAYGTNAAYGCNCARACNAAYGGNGGNYTNACNCCNYTNCAYATG GCNTGYACNGARGCNGARAAYMGNAGYATGYTNGARYTNYTNYTNACNAAYCCNTTYATH GAYATHTCNCCNGTNTCNGCNGCNGGNGARACNGCNAARCARYTNTGYGARMGNTGYAGY ACNAAYGTNGAYYTNTTYGARYTNYTNAGYGAYAGYATHAAYAARYTNAAR------CCN ATHMGNACNATGAARGARTAYGAYCARCARATHACNGAYYTNAARAARGARAAYTTYAAY YTNAARATGMGNATHTAYTAYATGGCNTCNMGNATGCARCARCARTAYGGNGAYGGNCAR GAYGTNYTNAARACNAAYATHGARYTNCARGTNGARATGGARAAYYTNAARAARGAYATH TTYGAYAARCARTGYYTNYTNCARAARGCNGCNGARYTNGTNGAYACNYTNACNTCNAAR CARCARCAYAGYGARGARGARATHMGNGAYMGNGTNACNGCNGARTGYGGNGAYGARYTN GARMGNYTNAARGCNYTNGTNGAYAARTCNCARAARGARTGYGAYAARTAYAARCAYGAR YTNCAYYTNGCNAAYGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ACNGAYMGNATGAARTCNCCNGCNCAYGCNCAY MGNACNAGYGTNTGYTGYTAYGTNTCNGGNGGNMGNGGNGGNTAYYTNTAYCARYTNTCN CCNAAYYTNGCNAARTAYYTNCAYATHGCNAAYAAYACNGGNGTNGARACNTAYACNTCN MGNTGGGGNGCNGTNTCNGTNGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TAYGCN CARTAYGGNMGNTTYNNNATHNNNNNNNNNAGYGAYNNNTAYMGNYTNCAYATHNNNNNN TAYNNNGGNACNYTNGGNGAYNNNNNNMGNNNNCAYAAYNNNNNNNNNTTYNNNACNTTY GAYMGNYTNNNNNNNNNNGARGARACNGGNNNNTGYNNNNNNNNNTTYNNNNNNGGNTGG TGGTAYNNNNNNTGYCAYNNNGTNAAYNNNAAYGGNNNNTAYGGNNNNNNNNNNTCNNNN NNNGGNYTNNNNTGGAARNNNTTYMGNNNNGARTCNATGGCNTTYNNNGARATGAARATH MGNCCNCARYTNCARCARGARATHCARGCNYTNAARACNGARAAYTCNGCNATGAARGTN YTNATHCARGARCARTCNCARAAYTTYTCNTCNATGATHCARCCNGTNGARAAYMGNGTN GARATHYTNACNGCNCARCARYTNAAYYTNAGYMGNGARGCNAAYGTNGAYMGNGAYGGN YTNCARCARCARATHTCNAARATHTCNYTNACNCCNGGNCCNCARGGNCCNGCNGGNGTN GCNGAYTTYTCNYTNTGYAARYTNAARTCNAGYACNAGYACNGCNGTNGCNAAYGTNAAR TAYACNGTNAARACNAAYTAYGTNCCNTCNGAYGTNCARACNAAY------TTYGCNYTN TTYGCNTTYTGYAARTTYAARGGNGCNGARGCNGTNTTYYTNCAYMGNGAYGAYCAYGGN TTYGCNCARCARTAYCARTGYGARTGYAARGGN--------------------------- ------------------------------------------------YTNMGNTTYGCN GGNTGYTTYCARTCNTGYTCNGGNGAYTCNGTNATHGAYYTNYTNTGYGGNGARYTNYTN GAYGARCARGCNGTNGARMGNYTNTTYGTNGTNAGYGTNCARGCNTCNTCNYTNACNGTN TGGATGGARGAYGCNGTNACNCARTGGAAYGCNGARYTNGARTGGMGNYTNGCNGTNGAY ACNCARYTNAGYAARTCNACNYTNATG--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARGCNTTYTTY GCNACNCAYYTNCCNMGNGGNACNACNACNYTNTCNGTNCCNAARTCNTCNGCNYTNYTN MGNCARGGN--------------------------------------------------- ------------------------------------------------------------ ---------------------ATGAARMGNYTNCCNAARMGNYTNACNTAYATHYTNMGN TAYGGNGCNATHAARGARGGNYTNACNGTNGAYGAYCAYGGNTAYGTNGAYYTNGAYCAR YTNATGACNGCNACNYTNYTNTCNGAYTAYACNMGNACNGARGTNTTYGAYAAYYTNAAR TCNTCNATHTCNACNMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNGTNCARAARATGCAR GAYGGNTCNGTNGAYTTYTTYMGNGAYTGGGARGAYTAYMGNMGNGGNTTYGGNACNYTN GARGGNGARTTYTGGYTNGGNAAYGAYAAYATHCAYTAYYTNACNTAYCARGARGAYACN ATGYTNMGNATHGARATGGARGAYTGGAAYGGNAARAARTAYCAYGCNGTNTAYGAYCAY TTYMGNGTNGAYGGNCAYGAYCARAAYTAYMGNYTNCAYGTNAGYGGNTAYCAYGGNAAY GCNGGNGAYGCNYTNACNTCNGTNTGGGARGAYCAYGAYGGNATGCCNTTYAGYACNAAR GAYAARGAYAAYGAYMGNMGNTTYTAYGAYTCNTGYGCNCARCAYTTYAARGGNGGNTGG TGGTTYAAYAAYTGYTTYGARGCNCAYYTNAAYGGNAARTAY------------------ ------------------------------------------------------------ ---------------------------------------------------------CCN ACNGAYMGNCCNYTNCCNGCNMGNAGYGARGTNTTYGARTTYATHATHTTYMGNGGNCAY GAYATHAARGAYYTNCAYGTNTGYGARCCNCCNAARCCNCARCCNACNGAR---GGNGTN CCNCCNGAYCCNGCNATHGTNAARTCNTCNCARCCNCCNCCNGGNCCNGCNGGNGCNGCN TTY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNYTNYTNATHCAYACNAAYATHTCNTTYACNCAR GTNATGGAYGARGCNGTNCAYYTNCCNTGYYTNMGNAARYTNGTNTAYCAYGAYATGCAR TCNTGGGGNGAYTTYGTNAAYCAYCAYCCNGARACNAGYATGAAYAARYTNGCNGCNYTN AARGTNCCNCARCAYTGYCCNGCNYTNGARTGGYTNGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TTYTAYAAYGCNTTYYTNATGATGYTNTTYGGNGCNACNCCNTCNAAY TTYAAYATHGTNTTYGTNGAYGCNCAYCCNTCNGGNGAYYTNGAYGARGTNTGGGAYGTN YTNTTYGGNAAYGTNCAYMGNGCNGGNYTNTTYAARGARGCNATGTTYTTYGAYAARYTN GTNTGGGGNYTNYTNGGNTAYTCNAGYCCNYTNAAYAGYCAYGAYMGNAARGARGTNCCN CAYYTNGARGAYTTYMGNCAYTTYTTYYTNACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYTTYCCNCARGARGTNGAYATHTCN TAYGARGAYTTYGCNCAYGTNGARAARATHYTNCCNTCNCARACNGTNCCNGARYTNCCN MGNTAYTCNTCNTAYCCNACNCCNTCNGGNTGGATHCCNCCNAAYGARGARGTNCARGCN MGNCARGCNTTYATHGTNMGNMGNACNAARAAYCAYGTNYTNCCNATHTAYACNTCNCAY AARAARCAYGGNGAYATHACNATGCCNYTNGCNTCNATHAARAARATHGARGGNGAYATH TGGTGYYTNGARGCNGARYTNGTNCARTTYYTNAARGARAARACNGGNATGGGNAARATH ATHACNCARGTNAAYGARGTNACNMGNACNGTNCAYGTNMGNGGNGARCAYGCNTCNYTN GTNGCNGAYTTYYTNYTNGARMGNGGNATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYYTNAARGCNAGYYTNGCNAARCCNYTNACNTGG AARCCNCAYACNGGNAARYTNCARCARGTNGAYTTYAAY------AARACNGTNYTNTCN GCNAAYACNAARGCNCCN---CARCCNGCNYTNYTNAARACNAARCARATGMGNGTNTCN GTNAARACNMGNCCNGGNCARGTNCARCARGTNGARMGNGCNGTNCAYYTNCARMGNMGN AAYAAYCARAARTAYATGGAYATGATGAARMGNMGNGGNYTNATG---TTYYTNTAYGAY CAYGGNMGNCCNCAYTGGTCNCARGGNGGNCCNYTNTTYTAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGAAYATH GGNAGYGARTTYGTNTAYYTNGGNAAYGARGARGAYGAYGTNGARGARGTNCARTAYGAR GCNAAYCARGAYATHGCNYTNTCNGAYAGYGAYACNTCNGAYGAYGAYGGNGARACNTGY YTNYTNGAYATHTTYGAYACNGCNGGNCARGARGARTTYTCNACNYTNMGNGARCARTAY GTNMGNCARGGNAAYGGNTTYGTNGTNATHTAYAGYATHGTNGAYMGNGARAGYTTYAAY GARGCNGAYGCNATGTTYAAYTGGYTNGARMGNGTNAARGAYGGNGAYCCNATHTCNGCN GTNYTNGTNGCNAAYAARCARGAYYTNGCNAGYATGGCN------GTNGTNAAYCARAAR GARGGNCARGAYYTNGCNGCNAARCAYGGNGTNCCNTTYTTYGARACNTCNGCNAARACN TCNACNGGNGTNAARGARGCNATGGARGGNYTNGTNMGNATHATHCCNMGNGAYTCNAGY GARTAYAARATHGTNATGYTNGGNTCNGGNGCNGTNGGNAARTCNAGYATHACNYTNMGN TTYGTNAAYGAYCARTTYGTNGAYGAYTAYGAYCCNACNATHGARGAYTCNTTYMGNAAR ATGATHACNGTNAARGGNYTNACNGCNATHTCNAARGAYCARAARAARGCNGTNAARAAR AARAARAARGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNGTNTTYGGNACNATHTAYCCNGCNTAYGCNTCNTAYAARGCNATGMGN ACNAARAAYGTNAARGARTAYGTNAARTGGATGATGTAYTGGATHATHTTYGCNATHTTY TCNGCNGTNGARACNTTYTCNGAYGTNTTYATHTCNTGGYTNCCNTTYTAYTAYGARYTN AARATHATHTTYGTNYTNTGGYTNYTNTCNCCNATGACNMGNGGNTCNAGYTTYYTNTTY AARAARTTYGTNCAYCCNCARYTNGCNMGNMGNGARAARGAYATHGAYGARATGATHGCN CARGCNAGYAARCARGGNTAYAGYACNYTNYTNTCNATHGGNCAYAARGGNATHTCNTAY GCNTCNCARGTNGTNATGAARACNGCNATHATGGGNCARTCNAARYTNGTNGAYCAYYTN MGNMGNAGYTAYAGYACNAGYGAYYTNTCNGAYGAYGGNYTNGGNYTNYTNCARMGNCAY CARGCNATH--------------------------------------------------- ------------------ATGCCNGCNAARACNMGNATHCARMGNGCNACNMGNATHAAY AAYATHGARGCNGCNMGNYTNCAYCARGAYATHMGNYTNGTNTCNYTNTCNYTNGAYTAY ATHCARTCNTCNAGYGGNAGYAGYCCNGARGCNTGGMGNCCNCCNTCNATHCAYGGNGGN GARGARACN------TAYAARTCNGARGGNCCNTGYTTYATGTAYGGNGARMGNATHATH AGYMGNAARACNMGNMGNCAYCARMGNCCNATGTCNGCNGTNGAYMGNACNMGNCCNCAR AGYAGYCCNGCNAARAAYMGNCCNATHAGYGCNATGCCNTGGYTNMGNYTNGARGARGAR YTNTCNTTYACNGARGAYACNCCNMGNCARAGYMGNCCNGCNTCNTGYGCNGGNMGNATH ACNCCNCAYCARGCNTGGGARGAYGARACNCAYGAYATHACNAARAARATHTTYAARGCN CARGCNMGNAGYCARTCNGGNTAYMGN---GAYCCNCAYTCNTCN--------------- ------------------------MGNGGNATHGCNMGNCARGTNMGNATHTCNTCNGGN MGNGCNAAYTCNGAR--------------------------------------------- ---AGYCCNGAYCARCCNCCNAAYYTNGCNCARGGNYTNGGNMGNMGNGCNACNYTNGGN GARATHATGAGYCARMGNMGNCCNACNATGAGYGCNGGNGCNTGGMGNGCNCAYYTNTCN CARACNGCNACNGCNCCNATGTCNACNAGYGCNCAYMGNGAYGCNYTNYTNAGYYTNAAR AARCARGTNAAYGARTCNMGNAARGARGCNGTNAAYAGYMGNGTNAAYGAYTTY---CCN GTNCCNGAYYTNTCNTCNYTNGCNATHCCNTCNACNACNMGNACNCCNAARAAYACNTCN AAYGARGGNTTYTCNAGYTTYCCNAARMGNGTN--------------------------- ------------------------------------YTNGCNAARCCNGAR--------- ---------------CARMGNGAYTTYGAYCARYTNGARTAYCCNGAYTCNGGNCCNACN AARGGNMGNTCNTCNCAYCCNGAYGTNACNAARYTNGARGARGARAAYATHMGNYTNAAR AARGCNYTNGTNMGNTCNAARGCNGAYAARTGGGTNAARYTNCCNGTNGARGAYACNYTN AARMGNYTNATGAARGGNGARCCNTAYTCNTTYGARYTNTAYAARAGYYTNCARGAYAAR YTNGARYTNYTNGAYAARGCNATHMGNAARTAYGAYGGNAAYGCNATHACNGCNGTNGTN ATGTTYYTNAARAARACNATHAGYCARCARATHTTYGARMGNGARYTNTCNAARMGNCCN GTNGCNGCNGAYCAYTAYYTNACNTAYYTNMGNGAYCAYTAYGAYTTYGAYCARTAYGTN GAYYTNYTNMGNMGNYTNGGNMGNTCNGARGARGCNACNATGCAYYTNTAYAARATGGCN YTNTCNACNTCNGAYACNACNTCNAARATHTCNMGNYTNAARAGYGCNYTNMGNAAYAAY TTYCARGCNGAYCCNAGYYTNGCNAGYGAYGCNTCNYTNATHCARGARTAYATHGAYYTN YTNGARAAYCARYTNCCNGTNGARCARTCNGAYGCNCARYTNGARGCNACNGGNAARAAY CARGCNTTYATHGARATHCCNMGNMGNACNTCNYTNGTNAAYATGTCNGTNGTNACNACN YTNTAYTAYTTYTGYYTNTAYCAYTTYGARAGYCARGARAAYTCNYTNAGYAGYCCNYTN GGNYTNMGNAARMGNCAYAARATHACNGAYCARCARTTYATGTGGACNTCNGTNTCNGCN MGNGCNAARMGNAARTCNTGGAARGAYGTNGARAGYYTNYTNACNACNAARGGNTGGTTY GGNGGNACNAARYTNAARGCNGTNATHGGNTTYGAYAARATHGTNGGNATHYTNCAYAAR AAYAAYGCNCCNATGGARGTNYTNAAYAARTAYYTNGCNYTNATGGAYGAYCCNGARCAR MGNYTNAAYYTNGCNAARAARGTNGGNTGYCAYMGNGCNGTNATHGAYACNTTYATHGCN YTNAARGAYAARTCNTCNYTNCARAAYTAYACNTCNAAYYTNGAYMGNTAYTCNCARGAY GGNMGNTTYGCNTCNGAYGTNYTNAAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATHCARACNTCNGGNTGYGCNCARGTNGAYCAY MGNAARGARAARGCNATHATGCARCAYYTNMGNTTYATHGAYCAYGARAARAGYYTNAAR AGYMGNTAYGGNCCNYTNGTNGAYYTNCCNGAYTAYACNTAYATHGGNGAYGGNMGNTCN GARYTNTCNYTNTCNCARAARGARMGNCARGARCARAAYTAYTCNYTNTCNAARCARGTN GTNCARATGGTNGARGARATGAARTTYGCNCARGARCARTTYACNGCNGGNGARAAYTCN AARMGNGARCARMGNYTNAARMGNGARTCNTCNMGNYTNAARTCNAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TAYTTYATHYTNACNATGGCNACNTTYGAYYTN ATHTCNTGYGTNATHGGNATGCCNACNGARATHTAYGAYYTNAAYAAYCCNTAYACNTTY TAYAGYACNGTNGGNTGYAARGTNTTYMGNGGNTGYNNNACNTTYACNGTNYTNGGNTCN GCNATHGTNYTNGTNGARATHGCNTTYGAYMGNTAYTTYAARATHTGYMGNCCNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGTCNYTNGAYATHGTNGCNCARTCNYTNGARATGGAY------YTNMGNGAYGCNCAR GARCARTGYAAYTCNAARAARTCNAARAARAGYAARGGNACNAAYGCNATGGAYYTNGTN AAYACNGAYMGNMGNGGNATHTGGAARCARYTNMGNAARGTNCARAARGCNCARGTNAAR CARGTNATHGAYAARAARAARCAYGARAARTTYAARTCNACNYTNGARYTNTAYAARGAR CARAAYAGYGTNGAYAAYACNAARGCNAAYATHGARGCNYTNCARMGNYTNACN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAY MGNAAR---ATHATHGARCAYATHCARGARCARAARAARMGNYTNCARCAYGGNCAYCAY AGYAGYACNAGYAGYGCN---TCNAGYTCNATHGCNGGNACNGGNTCNTCNYTNYTNAGY AAY---CCNTCNACNGTNCCNCCNYTNTCNCARGCNGARTAYGCNTCNATHAGYAAYCCN CARCARMGNGCNGCNYTNCARCAYGCNCAYGTNAAYTCNGTNGGNTAYTTYATHACNCAR GAYTCNTCNTTYGGNAAYYTNATHYTNCCNGTNYTNCCNMGNATH--------------- ---------GGNGGNTAYCCNYTNAAYCCNGGNCCNAAYGCNACNGTNCCNGGNGGNYTN GCNAARCARTTYTGYCAYATGGTNCCNGGNTGYAGYGARGCNYTNTGYTTYGCNTTYMGN ACNGAYAAYACNGGNCCNCCNATGAAYGTNTCNGARATHYTNAAYTAYTAYAARATHYTN MGNACNGARTTYCCNGGNGCNGAYGTNGTNGCNTCNACNTTYGAYAAYTTYGTNGARGAR GCNTGYMGNCARGGNGCNTGYCARCCNAAYGAYCAYMGNATHTGYGARATGATGMGNTAY YTNATHAARYTNCCNGARCAYACNTGGGGNGCNCAYAAYTTYYTNGAYACNATHTCNTGG TCNAAYGCNGCNYTNGCNAGYAARMGNAARACNACNATGTAYCARGAYGCNCARAGYGCN TGGAAYGARCARMGNCARTTYATHGAYYTNGGNATHAGYGCNYTNAARGAYCAYCCNGTN AARAARGCNATHCARAARGARTTYGARGAYATHACNGCNACNMGNCCNGAYYTNMGNGGN TAYYTNCCNGTNAARYTNTCNGAYGARTTYAARTGY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GCNGGNATGYTN GCNGAYCCNGCNAARATHGCNAARGARMGNGARMGNGARGARMGNGTNMGNCARGCNMGN GARMGNYTNGCNGARGARMGNMGNAARAARYTNGARGARYTNAARGARCARCARMGNYTN GCNCARGARAAYMGNGARAARCARYTNGARATGMGNMGNCARAARATHGARGAYYTNMGN MGNMGNGAYACNGARMGNMGNGCNGCNGTNGARGARMGNMGNAARATGAARGARGARGTN GARMGNGCNMGNMGNGARTCNATHYTNCARAARGCNGARGARMGNGTNGCNMGNTAYGAR GCNTGGAARGCNGGNGGNMGNAARGGNGCN---------------------------TTY GGNGGNGGNGTNAGYACNCCNGAYGCNAAYAGYTCNTTYTCNTCNATGGGNCCNAGYCCN TCNGCNTTYYTNTCNACNTCN------TTYCAYTCNGGNNNNNNNNNNNNNATGCCNAGY CCNGTNMGNYTNMGNGARMGNACNACNCCNMGNAARCCNMGNCCNAAYAGYGTNGCNTCN TCNATGCCNAGYTTYGTNGGNGCNGARCCNGCNAARAGYGCNMGNAGYAARAGYTCNGAY MGNGCNGCNMGNGAYMGNTCNAARMGNMGNAARGAYAARTCNAAYAGYAARAARYTNAAY ---------------------------------------GARMGNGAYGGNGGNGARGAY GGNACNGAR---------AARAARGARAARAARGCNMGNACNTCNAGYAAYTTYTAYGAY MGNYTNGCNACNCCNAARTTYCARMGNGGNTCNYTNCCNGAYACNCCNMGNGARCCNGTN CCNAARAARGAYGCNCCNYTNATHMGNYTNTCNCCNMGNAARGCNTTYTCNACNTCNAAY YTNGCNAAYATHMGNAARAARCCNTCNYTN---------AARGARAARAGYGTNAARGAR GCNGCNCCNAARMGNACNGCNACN---------------ACNACNCCNACNCCNAGYAAY GCNAGYAARGAYTCNCCNGCNTCNTCNCCNMGNGTNMGNCCNACN--------------- ---ACNTCNTCNACNGCNTCNCCNMGNGTNACNCCNCCNCCNACNGGN---------CCN ACNYTNGCNAAYACNAGYACNACNTCNGARCCNGCNAARAAYACNTCNATGCCNACNTCN TCNTCNGCNCCNGARGAYGGNGCNGCNGCNCCNGTNMGNGGNACNGGN---CARGAYATH TCNGCNGARGCNTAYAARGCNAARYTNGCNGARAARMGNMGNCARGCNMGNGARAARGCN GARAARGARGCNGARGARGARMGNCARMGNCARGARGARYTNMGNYTNCARGARGARGAR MGNYTNGARCARGARGARGARGARCARMGNMGNCAYGARGARGARGCNYTNACNATGGCN GCNGARGCNMGNAARGCNGARCARGARMGNYTNCARMGNGCNATHGARGCNGARGARAAR MGNAARAARGARGARGCNGARMGNATHGARGCNGARMGNAARATGAARGARGARGCNGAY MGNAARGCNAARGARGARGCNGARMGNCARGARMGNGARAARCARGARMGNTCNMGNAAR GCNGARGARGARMGNYTNGARMGNAARAARAARYTNGARATGATHATGAARMGNGTNAAR ACNGAYCCNGTNCAR---------------------GAYAGYCARGCNAGYACNAARATG GAYAGYCCNACNAARACNGTN---------------GTNTCNCCNCCNMGNAGYGGNYTN TCNACNCCNGAYGARYTNGAYAAR---------CCNTCNGGNCARYTNAAYACNGARAGY GAYYTNGAYGARYTNMGNCARCARYTNGGNGGNMGNGTNGTNGARTCN------------ ------------CAYACNGTNACNAAYCAR------------------ACNAAYTCNGGN GGNGTNACNACNACNACNACNACNACNTCNGARTGGAAYAGYTCN--------------- ------------------------GAYAAYGGNMGNGGNGARTCNCCNAAYTCNTCNCCN ACNCAY---------------------------------AAYACNAAYTCNTCNACNACN ACNACNACNTCNMGNTTYGAYGAYAGYGGNAGYCARTCNCCNGAYTCNGGNTCNGARGTN AARTCNAARTTYMGNTCNCCNYTNYTNCARAARYTNGTNGARAAYAARGGNGGNGARCCN GCNTCNGGNGAYMGNYTNAARTTYAARTCNCCNYTNYTNCARAAYYTNYTNGGNAARACN AARGTNGGNGCNMGNATGGGNYTNTCNAAYAGYYTNTCNGAYYTNACN---AAYAARGAY ACNGCNTCNCCN------------------------TCNAGYACNGCNGCNACNTCNCCN ACNAGYCCNACNACNGGNTCNATGAARGARATHGCNMGNCCN---------GARGARAAR GARGTNGAY---------------------------------------------ACNACN ACNGTNACNGGNAAYGGNYTNACNAAYGGNYTNAARAGYMGNGCNMGNGGNGAYGAYAGY GAYGAYAAYAAYACNTCN---------CCNCARGAYGGNATGMGNGAYTCNGCNYTNGGN TCNAGYATHGGNCCNCAY------CAYGGNGAYGGNGAYTTYYTNAAYCARTCNACNATH YTNAAYGGNCAYAGYGGN---AARGAYAARGAYGCNATGAARGAYTCNAGYATHGGNGTN GAYYTNGARGCNACNCCNAGYACNAGYGCNTCNYTNCARGAYTTYGGNTCNTCNGAYAGY AAYYTNACNTCNGGNCAYACNGGNGGNGGNGAYGGNCARTTYGARGARTAYATHGAYYTN YTNGAY------------GCNAAYMGNGGNGGNGCNTCNYTNCCNCCNATHATHGCNTTY GARGGNAAYGCN---MGNATGGCNGAYGTNTCNGARTCNYTNTCNGARGTNACNATGATG GTNGARATHCCNYTNCCNGCNAAYATHCARAARAARCAYGAYATGCAYATHCARYTNYTN GGNYTNTGGTCNGARGARCCNGTNGCNAARYTNGAYGAYATGYTNTAYGAYGGNGARATH CARCAYGCNGCNGGNTCNCAYYTNTTYGTNGARYTNAAYAAYACNGARTCNACNAAYTCN ACNATHGARACNGARCARTCNGTNYTNGTNTCNGAYGTNAGYYTNAARYTNATHCCNATG TAYYTNGARGARAAR------------GGNCARATGGCNGARTCNAARTCNCCNTGGMGN YTNTCNATHATHTCNGAYATHTTYTGGGCNATHATHAAYTTYATHGTNYTNTTYTTYCAR ACNATGTTYAAYCCNGGNAARAAYTCNMGNGGNGARGGNTTYAGYACNGAYTAYMGNMGN CCNGGNGGNGGNGGNCCNCCNTCNMGNMGNATGGGNGGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GAYATGTTYGGNGAY GGNYTNGGNAARAARAGYYTNATGCCNGARATHTCNCARGCNTTYAAYACNGTNAARAAY MGNYTNGAYTCNTCNYTNTCNAAYGAYGARGAYTCNCARMGNTAYYTNTTYGARGARGCN MGNGTNAGYGCNGGNACNATHYTNYTNCARYTNTCNMGNATHATHTAYTAYTAYGAYAAY ATHTGYAAYCAYATHCCNMGNTCNYTNGARCAYCARYTNATGTCNACNTTYTCNGAYYTN ACNGCNGAYGTNCARYTNGTNCCNMGNGARTGGCARACNATGGCNATGAARGARGCNTAY YTNMGNAARYTNACNGARGCNCAYAGYGAYGAYGAYCARGAYAARGTNAARMGNYTNYTN GCNAARGGNTCNGGNGGNYTNCCNGARATHGTNGARGAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GTNCCN TAYTTYCARGAYAARGGNGAYAGYACNAGYTCNGCNGGNTGGAARAAYTCNATHMGNCAY AAYYTNTCNYTNCAYAGYMGNTTYATGMGNATHCARAAYGARGGNACNGGNAARAGYTCN TGGTGGGTNATHAAYCCNGAYGCNAARCCNGGNAARACNCCNMGNMGNMGNGCNGGNAGY ATGGARACNAARAGYTAYGARAARAARMGNGGNMGNGTNMGNAARAARGTNGARGCNYTN MGNGCNYTNGARAAYGGNGGNACNYTNTCNCCNGGNGGNAGYGARGAYTAYYTNGAYAGY TTYGGNGAYTTYMGNCCNMGNGCNAGYTCNAAYGCNAGYAGYTGYGGNMGNYTNTCNCCN ATHCAYGCNGCNGCNGARCCNGAYYTNCAYGAYAAYCARGTNCCNCCNATGTCNCCNATH CCNTGGGGNGCNGARGTNAARCAYTCNCCNACNYTNTTYCCNGGNGAYTGYTAYTCNGAY YTNGTNGAYTCNYTNGGNGAYGGNATGAARYTNTCNAAYGCNGARAAYYTNAAYYTNGTN ACNGGNATHCAYGAYCCNTAYYTNTCNGGNTCNCCNCAYGAYTTYAAYAAYCARGGNCAR AAYTTYYTNATGGAYAGYCCNTAYTCNCAYYTNCCNGCNCCNCCNTCNTAYACNGARACN ACNGCNATHGTNGARGTNGAYCAYGARAARATGMGNACNGTNGGNAGYMGNAAYATHGAY GAYACNGTNGCNGTNCAYATGGCNACNGCNCAYCCNMGNATHGAYTCNGAYGGNACNATG TAYTAYTAYAGYACNAAYTTYGAYACNMGNAARGCNTAYAAYATHGTNAARATHCCNCCN CCNGCNCCNGGNGARGCNCCNTTYGAYAAYGCNCAYATHGTNGCNACNGTNCCNAGYMGN TGGAARACNGCNATHGGNTAYACNCAYGAYTTYGGNATGACNCCNAAYTAYTTYGTNCAY ATHGARATHCCNGCNGTNATGAGYATHYTNAARYTNATGACNATGAAYYTNACNGGNGGN ACNCCNGTNGAYYTNAARGARTTYCCNGGNGARCCNACNMGNGTNAAYGTNATHAAYMGN AARACNGGNGARAARGTNCCNATHACNTAYTAYGGNCCNCAYGGNTTYATHTTYCAYATH ATHAAYTGYTAYGARGARGAYAAYTAYYTNATHTGYGAYATHTGYTTYTAYGAYAARGAY GTNCCNAARYTNTAYYTNAAY---------MGNATGTTYGAYCCNGAYCARTAYGARGCN CAYTTYGARMGNTTYGTNYTNCCNYTNGAYATHTCNGAYGCNAARGARAAYGARAAYYTN GTNAARYTNGCNGGNTCNAARGCNACNGCNATGYTNCARGGNAGYAARGAYGTNATHAAY ATHGTNCCNGAYAAYCCNTTY---GGNAAYGTNATGTTYGARYTNCCNMGNATHAAYCCN AARTAYAAYACNAARGAYTAYMGNTAYTTYTAYGGNTGYACNGTNTTYAAYTTYAARTCN AARAARYTNTTYAARTTYGAYGTNAARACNAAYACNGTNAARGARTGGAARAGYGARGAR ACNCAYCARCCNTCNGARCCNGTNTTYATHGARAGYCCNGAYGCNYTNGARGARGAYGAY GGNGTNATHYTNGCNGCNGTNYTNAGYACNACNACNGAYTAYTCNTCNTAYYTNATHATH YTNGAYGCNTCNAGYTTYAAYGARYTNGCNMGNGCNGARGTNCCNTCNCAYATHAARATH AAYATGGCNTTYCAYGGNGARTTY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MGNYTNCCNGGN CCNTGGYTNATHATHGARTTYATHTAYTAYTGYGTNTAYGTNGTNYTNTAYATHATHGCN TCNATHGTNGCNGTNTGYAARGCNAGYYTNGCNCCNTCNGTNGGNGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGTCNAGYGAYGAR---GAYTAY ATGTCNGAYACNTTYYTNYTNAARTGYGARAAYAAYTGYCCNGGNYTNGCNAARAARAGY CARCARAARCARCAYGCNAARGARMGNAARGARAARGAYGCNAAYAARCARAAYATHCAY ATHTCNAARAARAARATGGARGCNCARAARMGNGAYGARGGNYTNGGNACNAGYATHTCN AGYGTNAGYAARGGNTTYAARATGYTNCARAARATGGGNTAYAARCCNGGNTCNGGNATH GGNAARAARGARTCNGGNMGNACNGARCCNGTNCCNATHGARGTNAARGCNGGNMGNGCN GGNTTYGGNAARGARGCNGAYATGAARMGNAARTCNGCNGARATGAAYMGNATGMGN--- ---------GARAARAARCARAARCARGCNGARACNCARMGNACNTCNTTYYTNGARMGN ATGAGYGGNAARTTYTCNGARMGNAAYGTNGARMGNGAYYTNAARATHGCNCARMGNGGN TGYYTNCAYYTNGAYGARGARCARGGNGTNCARGARCCNCARGARCCNTAYTTYTGGCCN CARGCNGARGARGARAARAARGGNTCNGAYGARGARGARGARYTNCARMGNTTYAAYAAY GAYTAYACNAGYCAYYTNTCNAGYGAYATHGAYAAYGAYTGYTAYGAYGAYGAYGAYGTN CCNGAYCCNGAYYTNCCNGAYTCNGARAARYTNYTNAAYYTNACNAAYTAYYTNMGNGCN ACNTAYAAYTAYTGYATHTGGTGYGGNACNMGNTTYGAYGAYCARAARGAYYTNGAYTCN AAYTGYCCNGGNAAYMGNGARGAYYTNCAYGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MGNAARMGNYTNGARGCNTCNGAYTTYYTNCAR AAYGTNGTNTAYATHACNGCNCCNYTNCARGCNGAYGAYAARATHGAYMGNTAYYTNACN YTNTCNAAYYTNTAYAARGARATHGGNTTYAARMGNAARGCNGGNTTYTTYAARMGNGTN TCNGGNATGCAYTGYATHATHCCNGAYGCNTCNCCNAARTGGTCNCARTGYTAYGAYATH ATGYTNCARTGYATGGARGGNTAYGAYYTNTCNGTNAAYCCNACNGAYATGGAYAARMGN AARAGYMGNGGNTGGCCNGTNYTNCARTAYAGYGTNYTNTCNGARYTNATHTAYGCNGCN MGNMGNACNAGYAAYCCNCARATHGCNGTNMGNCAYATGGCNYTNATGGTNCAYMGNYTN YTNACNCAYATHAAYGTNAAYGARCARMGNGARGTNYTNAGYAAYYTNACNACNYTNTCN TCNAARTGYCCNGGNAGYGCNYTNCCNATHCCNYTNGAYAGYGGNYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GCNGARYTNCCNTGYMGNATHMGNCAYYTN GGNACNAARMGNGTNTCNTGGMGNMGNGTNGARCARGAYAARTTYYTNTCNGTNGGNGCN GTNGTNTGGGCNTCNGGNACNAAYGTNGTNATHCARCAYACNGARCARGGNGARGAYYTN GAYGAYTGGACNYTNGTNYTNATGAARACNATHAARACNGAYGCNGGNATGTAYGARTGY AARATHACNTCNATHATGGARGAYCAYGTNMGNGTNCARYTNAAYGTNGTNGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GGNAAYYTNCAYGCN AARAARGTNTTYCAYGTNGTNGGNCCNAARTGGAARGAYTTYCAR---GAYAARMGNAAR TGYGCNGARACNYTNMGNCAYAGYGTNYTNMGNTGYYTNGGNGTNGCNGCNMGNCCNGAY GTNMGNTCNATHGCNYTNCCNTCNATHAGYGCNGAYACNTAYGGNGTNCCNAARGARGTN TGYGCNGARAAYTAYATGAARGCNGTNAARCAYTTYGAYCAYATGACNAARTAYACNAGY GTNAAYAARATHYTNTTYGTNGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR AGYGTNCCNATHACNGGNCCNATHYTNYTNGCNGTNGGNGGNYTNATGYTNYTNYTNGCN TTYMGNCARTTYTAYATGGCNMGNGCNMGNAARAARGARGGNGAYGARGGNTTYCARGCN MGNGAYGARGARGTNCAYGARTCNATHGCNTCNYTNCAYCCNAGYGCNAGYGARYTNAGY ATHGAYACNGAYTTYACNGCNCARTGYTTYMGNTGYGARTTYTAYGGNAARGARCAYTTY AAYTAYTAYGCNYTNGAYGARGCNYTNGGNCCNGTNGTNYTNTCNATGAARGCNGARCAR GAYCAYTCNGAYAGYATHAAYGCNATHGTNMGNACNAARTAYCARACNAGYGARGARGAR YTNTTYGCNAAYAARTCNCAYAGYCCNGCNYTNGAYGCNTTYYTNAGYACNATHGGNGAR MGNGTNMGNYTNAARGAYTTYAARGGNTTYMGNGGNGGNYTNGAYACNAAYCAYGGNCAR ACNGGNGARGARTCNATHTAYACNAARTTYAAYGGNAARGARATHATGTTYCAYGTNTCN ACNYTNYTNCCNTAYACNGARGGNGAYTCNCARCARYTNGTNTTYCARGARGARAAYACN CCNTTYGTNCCNGAYATGATHGCNTCNCARTTYYTNCAYTGYTTYGTNGTNGTNCAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GTNATHGGNGARGTNGARACNAARTGGAAYGAYYTNACNGARYTNYTNGTN CARCARGTNTCNYTNGARGCNYTNTCNGARATHGAYGGNATGYTNAARYTNAARGCNAAR MGNAAYGCNGTNAARGARATHATHGAYAARTGYACNMGNATGYTNMGNGARACNGCNAAY TCNCARACNGAYGARATHAARTCNMGNYTNGAYTCNATHAAYAGYCARGCNGAYYTNYTN TGYCARACNAGYGCNGAYMGNYTNCARCARYTNATGGAYYTNCARTAYGGNATHGARACN AAYAAYAARTTYAAYGTNTTYYTNATHGAYGAYGARGAYATHYTNGARAAYYTNGGNAAR CARGAYGAYCCNTCNAARACNAARAARAARGAYGAYGGNGAYAARAARTCNGCNAARTCN AARCARAARAARGTNGCNGARACNCARCCNAARGCNAARGTNGTNGARCARCCNGTNACN MGNAARGAY---------GAYAARCCNGTNYTNTCNMGNCARAGYGARMGNGGNMGNGGN ---GGNMGNAAYMGNGARCCNAARGARATHMGNGARAAYGAYGGNGAYMGNMGNCCNCCN MGNMGNCARGGN------------------------------------------------ ------CCNMGNGARAAYMGNGAYGGNMGNATHGGNGAYGARAAYGTNCCNCCNGARATG MGNGARMGNCCN---GAYAGYGGNTTYMGNMGNMGNGAYGAYMGNGTNGARMGNGARGGN GGNTTY---GGNGARMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNMGN---GGNMGNGGN GGNGARMGN---GGNGGNTTYGGN---CCNCCNMGNGGNGGNTTYGGN------GGNGAY MGNAARMGNGARTTYGAYMGNCAYAGYGGNACNGAYMGNACNGGNATHAARCCNGTNGAR AARMGNGAYGGNGGNGGNGCNCAYAAYTGGGGNAGYTTYAARGAYGAYGTNGARGARCCN CAYGCNAAYAAY---GCNGAYGARTCNGGNGAYTGGGGNACNCAYCCNGARGGNACNGCN GARAAYACNGARYTNAAYGARAGYAAYGARGCNGARCARGCNACNGARGARGAYCCNCAR GTNCARGARATGACNYTNGAYGARTGGAARGCNYTNCARACN---CARACNAARCCNAAR GCNGARTTYAAYATHMGNCARGCNGGNGARGGNGTNGAYAAYGCNCARTGGCARAARGGN GTNGARTAYCAYAARAARCAYGARGARGARGAYGAR---GARGARGARGTNACNTCNGAR GARGARGAYGARGAYGAYMGNCARGGNMGNGGNGGNAARAAYYTNGTNACNAAYATHMGN ATHACNTTYAAYGAYAAYCCNMGNMGNGGNMGNGGNMGN---MGNGGNGGNMGNGGNGGN ATGGARMGNGGNGGNGGNGGNGAYMGNGGNGAYMGNGGNAGYMGNGGNGGNTCNMGNGGN GGNGTNAARAAYATHGGNGGNMGNCCNMGNGARTCNGCNCCNMGNTTYGAYGAYGARGCN GAYTTYCCNTCNYTNGTNAARTCNGCNGCNMGNACNYTNTCNGGNGGNMGNAARAARTTY YTNTAYTCNGGNTCNGTNAGYGGNAARGGNCAYAAYCAYGARGARTGGTCNTTYGGNCCN AAR---------MGNGARGCNAGYCCNMGNGCNAAYATHCCNATHGAYYTNGAYAAYGTN TGGAGYATHMGNAAYGTNGGNYTNGGNAAYAGYACNGCNTCNGTNMGNTCNGARCCNYTN GCNTTYAARCCNGARATGYTNGGNAARAAYACNAAYTCNGTNTTYTAYTCNMGNCAYGGN GGNATGAAR---GGNMGNGGNCCNAGYCCNMGNGAYCARAARACNAAYGGNCCNGCNCCN ------------GCNCARTGGTCNAGYTCNGGNCAYAAYTTYTCN---CARGGNGTNMGN CARCARCCNCCNTCNTTYAARAGYCCNACNGARAARGGNTTYMGNACNTCNMGNATG--- AAYCARAAYCCNTCNCCNTTYGAYMGNGAYYTNAAYGAYTTY------------------ ------------------------ACNAAYAGYGGNAARTCNAGYYTNAGYTCNATGYTN TCNAARGCNYTNCCNAAYTGYAARTGGATGTGYCARGAYCAYTAYTTYYTNGCNGCNGAY GAYCCNMGNYTNGARCARGARGCNAAYGGNATGATHAAYTGGGAYAARYTNAGYGCNYTN GAYATGGARACNATGATGGARGAYGTNACNACNTGGGTNGARCARCAYCARGAYAGYACN AARCCN------GCNTAYYTNATHATHGAYGGNTTYYTNATHTTYAAYTAYAARCCNATG ACNAARYTNTTYGAYMGNAARTTYTTYATHGARGTNGAYMGNGARACNTGYMGNAARMGN MGNYTNACNMGNATHTAYGAYCCNCCNGAYTGYCCNGGNTAYTTYGARGAYATHGCNTGG CCNATGTAYCARAARAAYYTNMGNGARYTNGARGAYCARCAYGAYATHGAYTAYYTNGAY GGNGCNGAYCCNYTNGAYGARATHTTYGAY------YTNMGNGARGCNGCNMGNACNCAY GARGTNCCNTAYCCNACNYTNMGNGCNMGNGTNAAYGGNMGNACNTCNATGMGNAARATH CARMGNACNATHYTNAAYAARGARGARGARACNCAYYTNACNCARTGGYTNTCNGARTCN TCNMGNAAYCARGTNMGNCAYAARAAYACNAGYCARMGNYTNMGNGAYGCNAARATHCAR GTNGAYGCNAARAARCAYTTYATHTCNAARAARACNAARMGNAARTCNMGNAAYGCNGCN AARGAYGTNGTNGARGARAARAAYATGATHYTNGCNGARTCNCCNGTNGAYAAYGTNTGG GTNMGNAARTTYTAYCCNMGNCCNAGYTTYTCNATHGARGARTCNATHCARMGNCAYAAR TCNTTYGCNCARCCNGAYATGYTNGAYAAYATGGAYGGNYTNGCNTAYYTNGARATGATH YTNGAYTTYACNACNAARAARCARACNMGNTTYATGTCNGAYATHMGNTCNACNGTNATH YTNCCNCAYCCNTTYGAYTGGGGNCCNGCNCCNGCNATHYTNGTNATGTGYAARGCNGAR GARCAYYTNAARATGGCNGCNTCNYTNGGNGCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GAYGAYGARAAYGAYGCNGAYAGYACNTCN CCNTCNAAYYTNGTNCCNGAYAAYACNYTNTAYACNGTNGARGCNACNCAYMGNTAYGCN GGNGARGAYGCNGAYGARYTNAGYTTYGARGCNGGNGARATHGTNTTYGTNGTNGARTTY GARAAYAARGARGARCARGAYGAYGGNTGGCARATGGGNATHAARAARTCNGAYAAYAAR AARGGNGTNTTYCCNGARAAYTTYACNAARAARATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GTNTGGATHAGYCCNGTNTTYCCN MGNYTN---ACNAAYTCNTCNGAYAARGGNGAYTCNCCNACNAAYTTYAARGCNGAYYTN YTNCARTAYGTNGCNGCNTAYAARTGYCCNGCNYTNACNCCNTGGGARCARCAYATHAAR GCNCAYGAYTTYTCNAGYGCNAARGTNCAYATHATHGCNTCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARCCNGTNACNATHTTYTAYGAYGTNATHTCNCCNTAYACNTGGTTYGCN TTYGARGTNYTNTGYMGNTAYCARCAYMGNTGGAAYATHGAYYTNAARYTNCANCCNTTY TTYYTNGGNNNNATHNNNCANGGNTCNNNNNNNMGNNNNNNNNNNNNNAAYNNNAAYNNN NNNNNNNNNNNNYTNNNNNNNNNNNNNNNNNNNNNNNNNTAYNNNNNNGTNCCNNNNAAR NNNNNNNNNAAYCCNNNNGARTTYYTNTTYGARAARGGNAGYYTNAARGCNCARMGNYTN YTNGTNGCNTGYCARATHACNCARCCNGGNAARYTNGARGCNYTNTCNMGNGARTTYTGG ATGMGNGGNTGGAGYMGNAAYCARNNNATHTCNGANGARGAYGAYYTNNNNCARGCNGCN ACNAGYNNNGGNYTNAAYAARAARGAYTCNGAYGAYATGATHGCNYTNTCNAARACNCAR GARGTNAARGAYAARYTNNNNNNNTCNACNGCNGARGCNNNNGARYTNGGNGCNTTYGGN NNNCCNATGATHGTNACNGAYGTNAAYGGNAARAARAAYTGGATHTTYGGNAGYGAYMGN TTYCCNATHYTNGCN--------------------------------------------- ------------------------------------------------------------ ---------------------CCNGGNTGGNNNNNNNNNGTNNNNNNNNNNNNNATHNNN NNNYTNYTNNNNATGNNNNNNNNNNNNNNNNNNTCNNNNATHNNNYTNYTNNNNNNNAGY AARGGNGAYMGNYTNMGNYTNNNNCCNNNNATHYTNNNNNNNYTNTGYNNNNNNNNNGGN NNNYTNNNNYTNNNNGGNGAYNNNATHTTYGCNNNNNNNYTNNNNNNNYTNNNNNNNGAY ATHNNNCCNNNNGANGTNATHNNNNNNATNNNNTCNYTNNNNNNNNNNNNNNNNNNNYTN AGYTGGGGNTTYNNNYTNGAYATHGTNGCNTCNGTNGTNGCNNNNYTNNNNGGNNNNGTN NNNATHGTNGGNGCNMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AAYCARYTNTCNATHGTNGARMGNGGNYTNCARGTNATH GCNGCNAAYTAYGCNNNNNNNYTNTTYGGNAGYCAYCCNYTNACNMGNYTNGTNTTYGTN CCNYTNTTYATHTGGYTNYTNATHGARAAYCAYACNGGNTAYGAYYTNCCNTGGGGNYTN CAYMGNYTNAGYCCNAAYGGNYTNATGGGNGGNCCNCCNTAYCAYTAYGCNCAYCAYATG CARGGNTTYGGNCAYTAYCARCCNTTYTTYACNTAYYTNGAYAARYTNYTNGAYGGNGTN CCN---GCNAGYTAYAAYCCNNNNNNNNNNNNNTCNYTNCCNGCNCAYNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNN---NNNNNNNNNCARCCNYTNNNNCANNNNNNNNNN NNNGCNNNNNNNAARNNNNNNMGNGCNGAYNNNYTNNNNNNNNNNNNNNNNNNNGGNNNN NNNNNNAGYCCNCAYTCNTCNYTNGTNGAYACNYTNAGYTAYCARACNTAYGTNNNNCAR NNNTCNNNNNNNNNNNNNNNNGTNCCNGCNTAYAARMGNATHGCNATGGGNGAY---GGN GGNAARGGNGGNATHCCNGTNTAYCCNAGYCAR---YTNATGTCNCCNTAYCARCAY--- ---ACNTCNYTNATGCARYTNCARCARCCNCARTCNTTYATHCCNATGTCNTTY------ ------------------GCNGGNCAYCCNCCNGGNGTNCCNMGNTTYTCNTGYATHGAY YTNACNAAYGARACNCAY---ACNGAYTGGATHGAYYTNACNMGNTCNAAYAAYATHATG GAYTCNCCNGTNGTNGTNYTNACNCCNACNGAYGCNGCNGGNYTNACNMGNMGNMGNMGN GGNAGYGGNMGNMGNGGNTCNMGNMGNTCNYTNGTNCCNATGGTNMGNMGNTCNACNGCN TCN------------------------ACNACNACNTCNMGNACNGTNCAYGTNYTNACN TCNGAY---GAYAGYGAYTCNGAYAGYYTNCCNGAYGCNCCNTTYCARGTNCCNGARCAR AGYMGNGTNGTNAAYAGYYTNYTNGCNTCNCCNGARGGNATHAARATHAGYTGYCCNATH TGYATGGAYGAYGCNAARACNATHACNCARTCNCAYMGNCARGTNATGTCNACNACNTGY GGNCAYATHTTYTGYAAYGTNTGYATHCARACNGCNATHAAYGTNCAYAARGCNTGYCCN ACNTGYMGNAARAAYYTNACNAARACNAARATHCAYCCNYTNTTYATH------TCNGAY GGNYTNAARGTNACNGAYCCNAGYTCNAAYATHACNGTNTCNCCNAARGARGAYTAYMGN YTNAARMGNCARAAYMGNAGYMGNACNYTNCCNGGNATHAGYGARGAY---------AGY TCNCCNAARGTNCARMGNGCNAAYTCNCAYMGNGCN------------------------ ---------CCNACNCCNGARACNCARAARGTNAGYAAYAGYGTNMGNAARYTNGAYACN TCNMGNTTYACNGGNYTN---AAYAGYAGYAAYTCNGARCCNGCNTGGGTNAGYATGAAR AARAARAARATGGARCARGCNAGYGGNAGYGTNGARGAYAGYAAR--------------- ------------------GCNACNGARGCNGARTCNAGYGCNCARCARGCNAARGGNAAY GAYACNAGYCCNGCNCCNGCNCCNCARCCNATHGAYGCNTCNGAYAARAARGGNGCNGGN ATHGAYGCNACNAARAAYAARGARAAYAAYAGYCARTCNGARAARAARCCNGAY------ ---AGYACNAARMGNGCNAGYATHGAYATHGGNTCNGTNMGNAARCARAGYATHGARATH AAYGTNAAYGARYTNTCNGTNAARGTNMGNAGYAGYGCNTTYAGYAGYCCNAAYAARCCN GAYACNGCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYATHACNGAYAARAAR--------- ------ATHYTNAARAAR------------------------------------------ ------------------GCNAARGARYTNTCNGTNTGGATHGGNAARAAR---AAYGAR MGNACNAARTGYATHAGYYTNYTNYTNAARGGNGAYAARCARTCNGTNAARGARATHAAR AARYTNAARATHGCNAGYGAYGCNCARAARATH---------CCNCCNMGNGGNACNTGY CARTAYYTNAARTAYGCNTCNGGNYTNGARGAYACNGTNCCNCCNTAYTGGCARAAYAAR CARAAYGGNCARCARAARCARGAYAARYTNTTYGTNAAYGTNGAYACNCAYACNTTYAAY GCNATHGARAARYTNGTNGTNCARACNTGGAARMGNGGNYTNGTNGGNGTNGGNCARGAY GCNYTNAAYATHCCNMGNYTN---AAYATHAARGTNACNAARATHYTNMGNATHGARAAY ACNYTNYTNTTYYTNAARTAYAGYGTNYTNMGNAARACN------AARTGYGTNCARAAY ACNGAYTCNGTNTGYCCNTCNATGGAYAARYTNCAYGGN---AGYAARGGNGAYCCNGAR ACNAARGGNGTNYTNCCNACNTCNATGGARYTNGARYTNYTN---CAYGARGTNAAYGAR GTNTAYYTNTTYCAYGGNACNAAYCARGAYGTNGCNGARAARATHGCNAARGAYGGNTTY AARCCNAAYYTNGGNAAYGTNAAYGGNATGTTYGGNCARGGNTGYTAYTTYGCNGARAGY TCNACNAARTCNGAYCARTAYTCNGAYTCNAARGAYMGNAARGTNGGNCARGAY------ YTNGTNATGYTNYTNTGYMGNGTNYTNATGGGNAAYGCNTTYYTNTGY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MGNCCNGCNTGYTGY ACNGGNATHTAYYTNGAYGCNYTNGAYGCNMGNGCNGAYAARCARACNACNGTNGGNTCN CARCAYGCNTTYATGATGTCNGTNATGGAYAAYATGATGGARCAYYTNCARAAYYTNGAY YTNGCNAARGTNAARGGNAARATGGARACNMGNMGNGTNGGNGAYGGNTGYATHGTNGAR GGNTTYAARCAYGGNTGYGTNATGYTNYTNTGYTTYGAYGAYGTNCARGCNYTNGARAGY YTNTGGTCNAAYCARGARAARAAYMGNYTNTCNGCNYTNTTYCARGAYATHATGGTNGAY AARGGNYTNYTNCARGCNGTNCAYTGYGCNAARYTNACNATHMGNGCNAARATGTGGGAR GAYGARTAYYTNGCNTGYAARAARGARYTNYTNGCNMGNGCNAARGAYMGNYTNAARYTN GAYAARTGYGCNMGNGAYYTNGARATGGTNGARMGNGTNMGNGAYTAYCARAARGAYMGN TCNGARGTNATHATGAARGCNAARGAYACNGARGGNAGYTTYGARCARCARYTNGGNAAY TTYYTNYTNGTNACNAARCARATHYTNCCNCARTCNTCNACNAARYTNAARAAYGTNAAR GARTTYGCNACNAAYGTNAARATGGCNAARGGNGTNAARAARYTNAAYTAYTCNGCNGTN GAYGCNTAYYTNAARGCNYTNGARTTYTTYMGNAARGARTTYGARGARGTNGARGCNAAY ATHGTNCAYCCNYTNTGYCARGTNMGNACNYTNTGYGARAAYGAYAARCARMGNACNYTN AARAARGCNATHAARGGNGCNTGYGCNGARATGATHGCNYTNYTNAARCCNGARGCNGAY YTNCARAARGCNCARCAYAARGARTGGGARCAYAARATHYTNCARMGNGARMGNGGNYTN GCNTTYGGNYTNGTNAGYYTNGTNCCNATHAGYATGGAYMGNYTNTCNAGYATHGAYYTN AAYACNGAYGARTAYATHAAYGAYTTYCCNGARATH------------------------ ------------------------------------------------------------ ---------GCNATHTTYGAYATHGAYTTYTTYCAYCAYAAYCCNMGNCCNTTYNNNGCN YTNGCNAARGARYTNTAYCCNTCNGGNAARTAYMGNCCNAAYTAYATHCAYTAYTTYGCN MGNYTNYTNAAYGAYMGNGGNATHYTNGAYAARYTNGTNGARGCNCAYGGNACNTTYGCN AGY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARGAYMGNGARACNGAYCAYMGNYTNAAYATHGAYAARGCNAARYTNMGNAAR ATHGCNGTNGCNAAYGCNYTNCARAAYATGAARAARGGNGAYGGNCCNCARGTNGAYGTN ---------TGYGCNAARGCNGGNGGNAARTCNGTNAARGARYTNACNGAYTTYTGYAAR AARATHTCNGARAARGAYAARGARAARAAYGAYGAYGAYGAYAGYTCNGAYGARGAYGTN AAR---CCNGARAGYGAYGARGARGARATGYTNATHCAYCAYCCNTTYAARGTNAARGAR GCNTCNAAYAAYATHGTNATGAAYATHMGNAAYGCNMGNCARYTNCCNGTNYTNTCNAAY TCNGARAARCARGCNCARCARGCNTCNYTNMGNYTNGCNTTYCCNGTNTCNAGYGGNTCN CAYCAYMGNGCNAAYGARTCNGARTGGGTNCCNGTNGARMGNACNACNGCNTCNTCNTCN ACNNNNNNNNNNNNNNNNTCNACNNNNNNNNNNGCNTCNGTNTCNCARGCNGTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNAARGCNTTYCCNCARGCNGCNGAYGTNCCNGAYYTNATGMGNGTN TTYMGNACNTCNTGGAAYGARAARYTNMGNGARATHMGNMGNGCNGARAARMGNGAYGAR GARTAYATGAARGAYACNTTYMGNCARGTNTTYYTNGARTCNGTNTAYCCNGTNATGCAY YTNGCNACNYTNCCNGCNTTYMGNATGGGNGAYGCNGARAAYMGNAARYTNMGNCARGAR AGYGTNACNAARTTYGARGARGTNAARMGNTCNGGNAARGGNGCNYTNGCNGCNYTNYTN TCNCCNGARATGGTNTTYGARCCNTTYTGYATGGARGARGTNGCNTAYTCNGTNATHGGN YTNAAYTCNGTNAAYAARCARATGGCNGCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GAYGCNCCNCARMGN CARGAYGARCAYYTNNNNGGNAARCARCAYGCNGGNTAYGCNCARGTNMGNGCNGARGTN GARAARMGNAARCARAARGCNMGNGAYGARATHGARGCNMGNGARGCNAAYGARGTNMGN YTNMGNCARGARMGNGARGARMGNGARAARCARMGNCARAARGARMGNGAYGARAARMGN CARMGNGARMGNGARMGN------------GARAARGARMGNGARMGNMGNMGNMGNAGY MGNTCNMGNAGYCAY------------GAYMGNMGNMGNTCNMGNTCNMGNAGYMGNGAR MGNAARMGNAGYTCNAGYMGNGAYMGN------MGNMGNMGNMGNAGYMGNAGYMGNAGY AGYMGNGARMGNAARMGNAGYACNAGYMGNAGYMGNMGNTCNMGNMGNTCNTCNAGYMGN GAYAARAARTCNAAYMGNMGNMGNTCNMGNGARMGNMGNTCNAARAGYCCNMGNMGNTCN MGNTCNMGNGAYMGNAARGGNMGNAGYMGNGARGAYAARGARAGYAARMGNCAYAGYTCN GARMGNAARGARGAYTCNAAYAAYGARGARACNMGNTCNAAYAARACN------------ ---GARACNCCNGTNMGNAARYTNCCNAARAGYTGYATHAAYYTNYTN---GGNCARYTN AAYMGNCARGCNGTNAARGAYTGGCARGCNYTNGTNGARYTNCAYGGNTGGGAYTAYGAY MGNACNMGNAAYTTYYTNCCNGGNTGY------TCNGGNTAYTTYTGYGCNYTNYTNGAR GARCCNGARTTYCARYTNTAYACNGTNGGNGAYYTNMGNGCNGAYYTNAARAARYTNCCN MGNTTYGAYYTNYTNGAYGAYTTYGARAARYTN--------------------------- ---------------------------------------------------AAYGGNTAY GTNGARTTYGAYAARGGNGTNGARGTNATHGGNCAYATHTAYYTNAGYGTNGAYAGYGAY ACNGGNAARAARATHGAYTAYGTNYTNAAYGARAARGTNTGYAARAAYGAYAAYTCNGTN ACNTTYATHAGYAAYAGYTTYCAYGCNCARCCNGCNGARAARCCNAARCCNCCNCCNAAR AARTCNGAYGCNGARAARMGNAGYGARGAYAGYGTNGTNATGAAYGAYTCNGCNCARACN ---CCNAGYAGYACNAAYGTNGGNACNGTNGGNACNATGMGNAAYTAYTCNAAYCARGAY GGNTCNTTYTCNCCNGGNTCNAARMGNCCNMGNACNCCNCCNCAYMGNAARYTNGCNTCN AARGGNGCNGCNGGNAGYCCNGTNCCNAARTCNCCNMGNTAYCAYGAYTCNGGNGGNGCN TCNAARATGAGYMGNCCNGAYATHCCNGGNTCNATGAAYAAY---AAYTTYAAYGARGAY TAYGAR---TCNAAYTTYCARGGNGARGARGAYGAYAGYCARAAYTAYCCNAGYTTYYTN AAYCARGAYGAYCARAGYGCNTCNCARGARATHGAYCARAARCCNATHATHGAYCCNGAY ATHAGYATHGTNAARGARGARTAYATGTCNTCNAAYCARGGNCCNGGNGCNTAYTCNGGN AGYAGYCAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNCARATHTAYGTNCCNTGGAAYGTN CAYGARCCNGCNCCNGGNGARTTYAARTGGGAYGGNGTNTCNGAYYTNCAYCAYTTYYTN ACNYTNGTNCARCARCARGAYYTNGTNGCNYTNGTNMGNYTNGGNCCNTAYATHTGYGGN GARTGGGARTTYGGNGGNTTYCCNGCNTGGYTNYTNACNGARGAYCCNGAYATGGTNYTN MGNACNAGYGAYCCNTCNTAYATGAARTGGGTNAGYGTNTGGTAYAARGARYTNYTNAAY AARGTNAARCCNTTYYTNTAYACNAAYGGNGGNCCNGTNGTNATGGTNCARATHGARAAY GARTAYGGNAGYTAYTTYGCNTGYGAYAARATHTAYACNGGNGCNYTNMGNGAYATGGTN TAYGAYACNYTNGGNAARGAYGTNACNATHTAYACNACNGAYGGNGCNGGNGAYGGNTAY YTNCARTGYGGNAARGTNGAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AARMGN MGNGARTCNGARAARMGNTCNAGYGAYAARGGNTCNAARGAYCCNTCNGARCCNGARATG AARAARGCNAARYTNGAYTCNTCNAARCARMGNAGYYTNAAYGARAARGARGCNMGNGAR AARGARMGNGARMGNGARMGNGTNAARAARGARAARGAYAARAARGARMGNGARGARAAR GARGCNCAYMGNCARMGNGAYMGNGCNGARAARGARMGNAARGARAARGARTCNGCNGCN GCNAARCCNGARCCNGCNGTNGTNYTNYTNAGYGAYGARGARGARCCNTCNACNCARATG GAYGCNGGNGAYTTYGCNYTNGARATGGGNATHGCNTGYGTNGTNTGYAARCARTTYGAY GTNAGYTCNGGNAAYCARYTNGTNGARTGYCARGARTGYCAYAGYYTNTAYCAYCARGAR TGYCAYAARCCNCCNGTNACNGARGARGAYGTNAGYGAYCCNMGNTTYGTNTGG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TTYATHGTNATHGARGAYATH TTYGCNTAYGCNACNCARGGNAGYGAYGCNCAYACNGARMGNAAYYTNGCNMGNYTNYTN GCNGTNYTNAGYAAYACNACNTCNTGGATHTCNAARAAYAAYGAYGCNMGNMGNTGYCCN YTNYTNATGACNGCNTCNTCNGGNCAYGARAAYYTNYTNGCNGTNYTNACNCARTTYGAY ATHACNATHGCNTCNTAYMGNGGNCCNACNCARGAYGARCARGAYTCNTCNYTNACNTGY AAYACNAGYACNGGNTCNCARGTNGTNACNTTYTGYAARCARAAYAARTGYATGGTNYTN MGNTCNGTNMGN---ACN------------GTNAAYAAYGARYTNGTNCARATHAARGCN GARTCNGARGARGARATHYTNMGNMGNATHAAYGCNTTYATHMGNAAYAARMGNAAYGAR GTNAAYGARMGNAAYATHMGNGARTTYATHAGYCCNTTYTCNTCNGAYCCNGGNAAYAGY TGYGCNMGNGTNGAYGCNGTNTAYGTNCAYMGNGARGGNTCNAARAGYCAYATHACNYTN AARTCNGTNGARAAYYTNTGYGGNCCNCARACNATGACNTAYCCNGAY------GAYAAY YTNMGNGGNYTNMGNGTNCCNCCNGAYGTNGARMGNTCNGARGCNATHGARGARMGNATG GCNAAYATGGARGAYCAYYTNAAYATHACNMGNGGNAGYCARGAYGTNTAYMGNMGNYTN AARGAYYTNGARGARMGNATHATGTTYYTNGARGGNATHTCNCCNGARTAYTTYACNCAR GGNCCNCCN--------------------------------------------------- ---------------------------------GGNMGNAARACNGARATHGTNGTNAAY AARTTYTCNGAYAAYYTNTTYATHATHATHACNCARTAYATGAARYTNGGNACNATHGTN CAYGTNACNMGNGAYYTNATHAGYGAYGARGTNCARGGNYTNATHCCNATGTTYTCNACN AARGTNYTNYTNGGNAARGAYGARCCNYTNACNCAYGTNATGTCNAARGCNATHGTNACN GCNYTNAAYCCNACNACNTCNGTNATHYTNACNYTNGCNYTNAARAAYACNACNCAYGAY TGYGTNCARGARATHATHGARCARATHAARTCN------ATGGCNCARAAYATHCAYTTY GARGCNMGNMGNMGNCARGAYTTYGTNGAYMGNGCNTGYAARGCNMGNMGNCARATGGCN YTNGGNCARGARGAYAARCCNAGYGARCCNGCNACNCARATGCCNAARGARGAYACN--- ---YTNGTNTGYACNGAYCARGGNCARTTYTAYCARACNMGN------------------ ------------------------------------------------------------ ------------------------------------------------------YTNGGN TAYAARGTNCCNAGYCARACNATHGCNCAYYTNGTNCARAAYTTYGCNGAYGARAAYGGN AARATHAGYGTNGAYGCNTTYTTYACNYTNGTNGCNMGNYTNGTNMGNGCNTTYAAYYTN TAYAAYTCNCAYCARAARGAYAAYAARATGACNTTYTCNYTNGGNCARTGGYTNGGNACN TGYYTNGTNACNAARYTNTAYGTNCAYAGYGARACNCCNYTNYTNACNGTNYTNGARGAR CAYATGGGNACNGCNYTNGCNAAYTAYYTNATHCARGARCCNGGNATGAARGTNACNCCN GCNACNAARGCNMGNGARTTYAARGGNMGNGARGTNMGNYTN---------ATGCCNAAR TAYTAYGARGAYATHGARGARAARAGYGAYAARCCNAARTAYGCNTGYGARGGNATHMGN GAYGAYYTNYTNGARTGYYTNYTNAARAGYGAYTGYGTNMGNAARGARAARAARACNCCN MGNGARTGYATG---------TCNMGNACNGGNGAYCCNTCNGTNCCNGAYGCNTGYATH AARYTNMGNATGGCNTTYTTYGARTGYAARMGNTCNYTNYTNGAYATGMGNACNMGNTTY MGNGGNMGNAARGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CCNGARAARGCNCCNGCNGAYGGN---GGNYTNTCNACNGGNGGN AARGTNGCNATHGGNATHTTYGTNAGYYTNGCNATHATHGGNYTNTTYGTNGCNGGNTTY ATHTAYTGYAARMGNAAYAAYTTYACNCAYMGNAGYYTNAARGARTAYGTNACNAGYAGY GTNMGNTAYAARACNTAYAGYAAY---GCNAGYTTYAARGAYGAYGARGTNGCNCAYGGN GAYGARMGNTCNAARAARAAYGCNAARCARGCNAARYTNAAYMGNGARAARAARAARGCN TAYATHAARAGYYTNGARACNGARYTNGAYGAYYTNAARACNCARAAYGAYAARYTNTGY TCNGARAAYAARAAYATGAAYGTNGARATGACNGCNYTNGARGAYGARGTNGAYTAYYTN AARTCNGTNYTNGCNAAYTCNAGYGCNYTNTCNGGNYTNYTNCARAAYATHTCNGGNGTN AARGGNGTNCAYYTNTCNTCNTCNATHYTNAAYMGNAARMGNTCNAGYGAYCARGARCCN GARTCNGAYTTYCARGTN------------CCNTCNAARMGNTCNMGNTAYATHCARGAR AAYYTNAARAARGCNGGNGTNTGYYTNCAYGTNACNGGNGGNCARGCNAGYYTNGARTTY TGYGCNAAYTGYTCNAAYYTNGCNMGNAARTCNYTNYTNAAYMGNGAYTTYTCNGGNYTN CCNGARGAYTTYCAYCARGTNAGYTGGAARGGNAGYGCNGARCCNCCNTGYATHATGCAR YTNYTNTGYGAYMGNCAYGAYGGNYTNGTNGTNGARGCNAARACNATHAARGARCAYTGG TGGAARCCNCAYATHAARMGNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TTYGTNGCNGARCAYGCNGGNGCNGGNAAYCAYTCN ACNAAYAARGARCAYYTNTAYAARAAYGTNTGYAARCARGCNTGYYTNCARGCNATHACN YTNYTNAARTCNAAYMGNCCNGCNYTNGARGTNGCNACNGCNGCNGTNAARGTNYTNGAR GAYGAYGARATHACNAAYGCNGGNTAYGGNTCNAGYYTNAGYTGGCAYGGNGTNGCNGAR TGYGARGCNAGYGTNATGGAYGGNCARTCNATGACNTTYGGNGCNGTNGGNGTNYTNTCN GGNGTNAARAAYCCNGTNAGYGTNGCNTGYAARYTNGTNGAYGAYCARAARAARGGNCCN YTNCCNTTYGGNMGNATHMGNCCNAGYATHYTNGTNGGNAARGGNGCNCARATGTAYTGY ACNGARAAYGGNTTYGARGTNGAYMGNAAYYTNATHTCNACNTCNACNATGAARACNTAY AAYAARTAYAARMGNAARTGY---GGNATHGARAGYACNAGYAAYAGYCARAARAARMGN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGGAY ATGGAYGARYTNAARTCNGTNTAYTAYGGNYTNGARATHAARAAYGARCCNGTNGTNATH GAYGARCARGTNGCNGTNGGNGCNGTNTTYGTNAGYTCNAARTAYGGNCARCARTAYCAR TGYAGYTTYCCNGAYCAYACNATHGAYGAYAARAARAARGARGARGARGARAARATHGCN GARGARCARGGNATHGTNGARATGYTNAARCCNATGGGNTCNMGNGAYTGYYTNATHAAR AGYAARGAYTGGTGGCAYTAYGARTTYTGYTAYGGNAAYCAYGTNMGNCARTTYCAYATG GARGAYGGNGARATHAARGGNGCNATHATHTAYYTNGGNTAYTAYGARAGYGAYTTYGAY TGGGCNAAYGARACNGCNAARAAYGARMGNYTNAARAGYAARGGNTTYATHAGYMGNTAY CAYTCNCARTCNTAYTCNCARGGNACNAARTGYGAYYTNACNGGNCARATGMGNAGYACN GARGTNMGNTTYATHTGYGARGARAAYTCNGARGAYTTYYTNTCNMGNATHGAYGARTCN GARACNTGYGTNTAYACNGTNACNGTNGTNACNTCNMGNGTNTGYMGNCAYCCNTAYYTN AARCCNCCNGTNAARMGNAARCCNGTNGARATHCARCARATHAARTCNAGYTTYGCNACN TCNAARTAYAARYTNTCNAGYATHMGNACNAARYTNACNAARGARAARAAYTGGMGNTCN GARATHGARGAYGCNATHAARGARGCNGARGARGARCAYGGNGTNAARATHGAYMGNAAY GTNYTNTCNGGNYTNTCNAAYACNYTNGAYAARYTNYTNAAYAARYTNGARGAYACNGAR ACNGARYTNTCNTCNATGGAYGARGARATHAGYGCNYTNGAYMGNACNATGCAYGTNATH CARCARGARGAYGARGARGGNAARACNAAYMGNTAYATHTTYGTNTTYGGNYTNACNGGN TTYGAYGAYGARTCNGTNGARACNGARMGNCARGARAARATGGARGARAAYTAYAGYTTY GTNTAY------------------------------------ATHTCNGGNTTYATHTTY GGNTTYGCNYTNGARAARGGNMGNGTNYTNGARCCNGARGCNATHACNGGNCARATGYTN TTYGARMGNTTYACNATGATGAARATGTTYYTNTCNGCNTCNGCNACNGGNATGYTNGCN TTYTCNATHATGCAYATGATGCCNGGNACNGCNAARAARATGGARGARGCNAARAAYAAR TTYMGNTCNTGYYTNTGYTCNAARAGYTAYGCNAGYGCNGCNGTNGGNGGNGCNYTNYTN GGNTGYGGNATGACNYTNTCNGGNTCNTGYCCNGGNATGGTNTGGGCNCARATGGGNGCN TAYGTNCCNAAYGCNGCNTAYAARYTNYTNGGNGGNYTNACNGGNGCNYTNGTNTAYGCN GTNATGGARCCNTGYGTNAAYTCNATHTTYAARCCNACNMGNGCNATHCARCCNGTNTTY ATGAAYGARMGNTAYGGNACNCCNCARTTYGTNGCNGCNYTNCCNYTNACNGTNGTNYTN GCNACNGGNGTNTTYTCNYTNGTNYTNYTNTTYCCNGARTCNGARGARGCNGGN---GCN ------GGNACNAGYYTNTTY---GTNAARTCNTGGTCNCCNGTNGTNGCNGGNATHYTN ATHGGNTCNYTNCARATHCCNGCNGTNYTNTTYATHGARGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARATGTAYGTNGCNGTNYTNAGYACNCARAARACNGTNYTNCARGAYGARGCN GAYMGNATHTCNGAYGARYTNCARGAYGTNTGYMGNYTNTTYGARGARGARAARCARTCN CAYGARGCNYTNAARMGNACNTGGCARATGGCNAAYGAYCARTTYYTNGARTCNCARMGN YTNATGATGATGGAYYTNMGNMGNATGGARGGNGTNYTNACNATHGARCARCARMGNCAR ATHGCNNNNYTNCARCARCARGAYGARCARMGNGARGCNCARGARMGNAARATHAARGAR YTNAGYGARMGNMGNGARMGNGARGARGARMGNMGNAARYTNAGYCARTCNAARYTNGAR CARGARMGNAARMGNCCNACNTCNTCNTCNGAYGGNTCNGARGGNCCNCARGGNCARACN GARGGNGCNTCNGCNCCNGGNGAYAGYGGNYTNGCNGGNTCNGCNGAYGCNGAYGARGAY GCNCCNTTYATHGAYAGYGGNGTNCAYGAYACNCARAAYYTNGGNGGNAGYGAYGGNACN ACNGTNMGNATHAGYCCNGARAARATGCCNTCNYTNACNCCNGCNCARGTNAARGCNATH ACNGAYCCNACNCCNGARACNGARGCNCAYAARTCNYTNATGGCNAGYGTNMGNTCNAAR ACNGGNACNGTNAAYYTNYTNAARTAYCARTCNGARYTNGARGARGCNYTNAARAAYGCN TCNGARGAYGCNCARTCNCARATHACNCAYYTNACNAAYAARGTNATHGAYTGYGARAAR TAYATHCARGAYTTYAARCARCARATGACNTCNACNCAYATGCARYTNCARGAYCAYTGY AARTCNYTNTCNGARAAYMGNGARGCNGTNCAYCARGARYTNATHAARYTNCARGCNGAR AAYGAYAGYYTNGTNGAYAARTAYTCNAARACNGCNCARCARYTNCARAAYGARGAYATH AAYYTNCCNAAYAAYYTNGARGARATGCARYTNYTNYTNYTNAARTAYMGNGARGARATH ATHTCNGCNAARGTNGCNAARGAYCAYGTNGARGARACNYTNAARAGYGARATHGCNTTY YTNAARTCNCARGTNACNGGNGARCARCARGARMGNGTNACNYTNGARGARACNYTNACN CARGARATHACNTCNYTNCARACNAARYTNACNGARYTNGARACNGCNAARAARGARYTN GARCARGARTCNAAYAAYMGNGCNGARGCNGARACNAARGTNMGNGARYTNGARACNACN YTNAARGGNGCNCARACNAARTCNAARCARATHATHAGYAARYTNCARGARAARYTNGAR GARYTNGAYAARMGNAARAGYAARYTNGARTCNGARAAYCAYTCNATGAARGGNAARGTN CARTCNYTNCARGTNGAYYTNGAYAAYAGYGARGCNGTNCARMGNGAYTTYGTNAARYTN TCNCARTCNYTNCARATHCARYTNGARAARATHMGNCARGCNGARAAYGARGTNMGNTGG CARCAYGARGAYGAYATHGAYGAYTGYAGYAAYTGYAARCARCCNTTYTCNGTNACNAAR MGNAARCAYCAYTGYATGTTYMGNCCNGAYAARGAYYTNTCNTCNACNATGATGCCNTCN CARTCNCCNTCNCARATHTCNGGNTTYAAYGGNAGYACNAAYTTYTAYGGNCARGGNACN YTNCCNYTNCARCARMGNGCNATHGGNGGNAAYCAYTTYMGNGGNGGNAAYAAYGCNGGN CAYATHACNCCNACNAGYYTNAAYCCNGGNTTYCCNATHGGNYTNCARCAR---CARCAR CARCARCCNCARCARCARCARCAYTCNCCNAAYAGYYTNGCNGCNATHGGNCCNMGNAAY ATGYTNGGNGTNCARAGYCARGCNGGNCARCARAGYATGGCNAAYYTNCARAARMGNCCN TTY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGTCNGARTTYMGNGGNMGNGGN---MGNGGN GGNMGNAGYMGNGGNGGNCCNTAYMGN---GGNGGNCCNMGNGGNGGNMGNGGNGGNTTY ATGGTNGAYMGNGARGGNMGNGGNGGNGGNTAY---------MGNGGNGGNTAYTCNMGN GGNMGNGGNGGNCCNTCNMGNAGYMGNGAYGAYGARTCNCCNCCNMGNAARGGNATGTCN MGNGGNTAYGAY------GAYTCNGAYMGNCCNCCNCCNAGYMGNMGNATG---GAYAAR TAYGARGAYAGYTAYGAYMGNTCN---GCNMGNTCNMGNTCNMGNGAYTCNTAYCCNTCN CCNACNMGNGAYTCNGGNMGNGGNYTNGAYMGNGGNTCNCCNCCNMGNACNAGYTTYMGN GGNMGNGAYTAYGCNTCN---MGNAGYATGGAYTAYCCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGNGTNTCN AGYYTNGARACNAGYYTNGGNAARGAYACNGAYGTNGARMGNGTNTTYMGNAARTTYACN TTYAARTGYYTNCARATHATHGTNCARTCNMGNATHGARCCNMGNACNGTNGCNACNAAR GAYACNACNTCNGAYTAYTTYAGYATHTAYYTNCCNGAYAAYCCNGTNATHGARGARCAR ATHMGNMGNACNYTNGARGGNATHAARACNTAYCCNGTNACNGAYCARAGYATHTGYGTN GARATHACNYTNGTNACNAAYGAYGGNGAYMGNATGTTYYTNGARACNTGGGAYATHGGN TTYAAYYTNAGYAGYYTNGAYATGTCNGCNGGNAARATHCARCAYATHTTYACNMGNATG GGNGTNACNYTNAARTCNYTNYTNTGYGCNACNMGNGCNACNTCNGCNCAYMGNYTNGCN AARAAYCARGGNGARAARGGNGGNGGNTAYMGNYTNAAYTAYMGNTTYTAYYTNGGNAAR CCNYTNACNCAYYTNYTNGGNGAYGGNCAYAARACNATHMGNGCNGGNGCNGTNCCNACN GCNTAYGGNYTNYTNAAYATHAAYGTNTCNTAYMGNACNAARYTNYTNATHTCNCCNGAR ATGGCNGCNTCNGCNTCNGCNGCNATHGARYTNACNGAYAAYTAYTTYATGAARGARAAR AARAAYAARCAYGCNACNAGYCARCCNTCNTCNCCNCARCCNTGY--------------- ---TCNCCNYTNGAYAARMGNCCNATHCAYYTNCCNAGYCCNGAYAAYMGNGCNGARAGY CCNTAYTGYTTYGCNGTNTCNCCNTCNTCNTAYGAYCARGAYGARCAYYTNYTNTCNGCN ACNCCNTCNAARGAYCCNCAR------GCNTGGCCNYTNTCNAGYATHYTNAAYATGGAR GARYTNCCNGARCCNTCNATHGGNGCNTTY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNYTNGCNAGYYTNMGNYTNTAYTTYMGNCCNGARCAYACNCCN GAYGGNMGNCAYGAYGAYTCNGGNGARGAYGARATGGTNGTNYTNGGNGARAARYTNGTN YTNMGNYTNGAYGAYYTNGTNCCNYTNATGAARGARGAYTAYAARTGGCCNTAYGGNAGY ACNGCNATHTCNGGNMGNGCNCCNGGNTGYMGNGTNATGTTYTGYMGNGAYTCNTTYTAY CAYGCNGAYATHGAYGAYYTNGAYATHMGNATGGAYCAYATGATGCCNACNYTNAARATH AARAAYAARGGNAARAARGCNAARCARATHATHMGNAARGAYTCNCARCAYGAYTCNGAY AGYATGGARGARATGTTYGCNCAYGTNGCNCCNTCNATHTCNACNTCNTCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CAYATGYTNGTNATG AARMGNTGGAGYGCNGTN---TGYGAYYTNAARGAYATHATHAARGAYTCNAARAAYATH GTNGTNCCNGARCARTTYGCNCCNTGGYTNAARAAYAGYTGGATHAARGARAGYGAYTAY ATHCCNATGGGNAARAGYYTNAARMGNAARMGNGTNACNGARTTYYTNYTNGAYYTNGAY GCNGAYGGNYTNGARTCNYTNATHGAYYTNTTYTCNGARYTNTCNTCN------------ ------------------------------------------------------------ CCNGCNGAYTTYACNCARTTYATHTTYAAYMGNTCNCARACNGARATHCCNAAYATHACN TGYAARACNCAYGGNCCNTCNCARGGNCARCAYCCNGCNAGYCAYCARTTYTCNTTYAAY TCNGGNAAYCCNAAYTCNGCNTCNAAYAGYCCNATHGARCARMGNMGNCCNGTNAARGTN ATHAGYATHCCNCCNGGNGCNYTNTCNGGNGGNTCNGTNTCNCCNGCNGCNACNCCNCCN AGYTCNMGNCAYTTYMGNATGAAYTTYGGNGAYACNGGNGGNGTNTGYGCNGTNACNAAY CCNTGYGGNACNGGNACNMGNACNMGNCARMGNGARTGYGTNGGNAARYTNTAYGGNGGN AARAAYTGYGAYGGNAGYAARACNAAYACNACNTCNTGYAARAARGARCCNTGYCCNGCN YTNCCNYTNCAYTTYGAYATGGGNCARTGYACNGAYCARAAYTAYACNTGYGCNAGYAAR AARATGTGYATHYTNAGYATHTAYCAYTGYGAYTGGACNGTNCARTGYCAYGAYGGNAGY GAYGARATGAAYTGYATGGARGGNYTNAARYTNGGNGARMGNGARCARCARTTYTAYGCN GARYTNTTYCARGCNTGYGAYGTNGARGGNAGYGGNAARATHAGYGGNCARAARGCNTCN GARYTNTTYMGNGCNTCNGGNYTNAGYCCNGAYGTNYTNATHCARATHMGNGARYTNTGY GGNGCNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARACNGCNGAYCAYCCNGAYCAYGTNGTNCCNTCNTTY AARCCNCCNCCNGAYYTNAGYAARYTNGAYTCNATGCCNTCNTCNTCNYTNCCNYTNAGY TCNTCNCCN------YTNCAYAARCCNCCNCCNTTYGGNACNYTNAGYTCNACNTTYCCN GCNGGNCCNATHTTYCCNGAYTCNTCNAAYCARGCNCARYTNAGYGCNCCNGTNGTNACN TCNCAYGAYGGNAARTTYCARYTNACNATGCCNATHGAYGAYTAYAARCCNGARGARYTN TCNGTNAARACNCARGAYAAYAARGTNATHATHAGYGCNAARMGNCARGTNAGYGAYGGN AAYCAYAGYCAYACNATGGARATGACNMGNGARCAYAGYYTNCCNGAYAAYGTNGAYCCN TTYGCNGTNAARGCNTTYTTYACNGAYACNAAYAAYYTNATHGTNGARGCNCCNTTY--- ---YTNCAYCARGCNTCNTCNAGYCARGAYAARGARGAYGGNGAYTGYGAYTCNACNCCN ACNACNCCNTCNGAYAAYACNCCNAGYGCNAGYTCNACNTGGAAYAAYTGGCCNAAYCCN CCNGCNGGNCAYMGNATGGARCCNGGNMGNCCNCAYACNATHAGYTCNGCNTAYGARAAR GGNCAYGGNMGNCCNGCNYTNAARCCNGAYATGTTYGARCCNCCNCARGARGTNGTNGAR ATGMGNCCNAARGCNACNMGNTCNYTNAGYCARAGYAGY--------------------- ------------------------------------------------------------ ---------------------------TCNGARMGNAGYAARACNAAYTCNYTNAAYAGY AGY---------------TCNACNACNCAYAAYGARGAYGARGAYAARGTNYTNAARGAR CAYTCNGAY---------GARAAYTTYTCNAAYCAYGCNACNCARTGGATH---GAYMGN GGNTAYAARGARAAYTGGCAYTAYCARGGNAARGAYGCNTTYGARMGNCCNAAR------ ---------------------------------------------------------ACN GCNCCNGGNTGYMGNMGNAGYCAYACNTCNGAYGAYTAYAAYCARTAYCCNTCNAARTTY CCNGTNGARMGN---------------AAYTGGAAYCAYACNATGGAYGAYGTNTCNGAR ACNGAYTCNGARMGNMGNAGYATGAARMGNAARACNAGYMGNAARACNGCNGAYGGNGAR MGNTCNGTNGAYGARTCNTTYACNGAYAGYGAYTGYGGNYTNYTNGARATGTAYAARAAR ATGAAYAGYATGGCNATGMGNGAYTGYGARTGYGGNAARACNGGNACNAARTCNGGNGAY GARGARCCNCCNTAYMGNYTNAARGGNAARAARTGYTCNGGNAGYTCNYTNATHAARACN YTNGARCCNCCNCAYACNMGNAAYYTNGARACNACNGAYGTNTTYMGNMGNCAYCARATG TAYATGAARYTNTGGAARACNCARCCNGCNATHGGNGARAAYAAYMGNTAYGAYATGMGN AARATHGTNCAYGCNAARATGATGAARAARCAYAGYATHGTNTTYGAYGCNAARGTNTAY GTNCCNAAYGTNTAYATHCCNCCNCARGARAARMGNMGNGARAARYTNMGNTGGCARGTN MGNAAYGCNYTNGTNAARTAYGARYTNCCNCARCAYGGNGTNTAYCAYGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AARMGNAARYTNGARYTNGARGTNGCNTCNYTNAAR GAYCARYTNYTNMGNYTNAARCARGCNGGNCAYCCNTCNGARCARTGYAARGARACNGAR ATHTCNGTNYTNAARGTNCARGTNTCNGTNTTYATGGARGAYTTYAAYAAYGARAARAGY CARMGNAGYACNYTNGARAARMGNYTNGARGARATGAARAARGARAARGARGCNCARAAR YTNAARYTNGARACNAARGTNAARAARATHAGYGCNYTNYTNMGNGCNMGNGAYGARGAY YTNAGYAARAARAGYAARATGGTNTTYGAYYTNGARTAYGARAAYGARAAYYTNAARAAR AARYTNMGNGAYGARGARMGNAAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARATGACNGTNAARTCNATHATHGARGARGCNYTNYTN CARTTYAGYGCNGAYMGNATHGGNMGNCCNGAYTTYGCNYTNGARTCNGCNGGNGGNAGY GTNYTNGGNGTNMGNTGYTCNGARACNTAYTAYMGNAARACNGCNYTNGTNAGYGTNTTY GGNATHCCNYTNTGGTAYACNTCNAAYTCNCCNMGNACNGTNATHCARCCNAAYGTNCAY CCNGGNGARTGYTGGGCNTTYAARGGNAGYTCNGGNTTYYTNGTNYTNCARYTNTCNCAR CCNATHCARCCNACNGGNGTNACNATGGARCAYATHCCNMGNAGYYTNGCNCCNAGYGGN GCNATHGAYAGYGCNCCNAARGAYTTYGCNGTNTTYGGNYTNAARTCNGARAARGAYYTN TCNGGNAARAAYYTNGGNAAYTTYACNTAYGTNGAYAAYGGNAARCCNATHCARTTYTTY GGNATHCARAAYGGNAAYCCNGGNATHTAYCARYTNGTNGARYTNMGNATHYTNAGYAAY CAYGGNAAYCCNGARTAYACNTGYGTNTAYMGNTTYMGNGTNCAYGGNYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GCNAARCARATHGTNACNATHMGNCAYAARAARATG AARAARCAYCARYTNMGNAARYTNMGNAAYMGNATGTAYTTYYTNTGGMGNMGNCARAAR ATHGCNMGNMGNGCNAARMGNATGGARATHTAYTGGAARAAYATHACNGAYATHAARAAR CARGGNGARGAYTTYGAYGCNGARGCNTTYGTNAARGARCARYTNYTNAARGCNMGNMGN GGNGGNTTYTCNYTNGAYGTNTTYCCNTCNAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNYTNATHCAYACNGTN YTNACNCAYYTNAARGAYAARMGNCAYYTNATHGAYAAYGGNATGGCNYTNAARACNATH CAYYTNATGATGTCNYTNGAYTGYGAYGTNAAYATHAARGAYTAYTCNCAYAARTCNCCN YTNATGYTNGCNGCNGARYTNGCNTAYGCNCCNATHATHCAYGARYTNYTNCCNAARTGY YTNGAYTGGCARYTNCARACNCCNYTNCAYATGGTNTGYATG------------------ ------------------------------------------------------------ ---------------------------------------ATHATHATGAARGAYGTNMGN AARTAYTTYGCNATHGGNAARTAYACNGARGGNATGCCNGAYMGNCCNGARYTNCCNMGN GGNCARTCNGTNGAYTGYYTNATGGGNGTNCCNCARAAYCCNAGYAGYAARGCNAARATH CAYAARAGYYTNACNYTNATHGCNTCNTTYTTYTGYTTYGTNTCNGCNGTNGGNACNATG TTYATHATHAAYYTNAARATHATHTCNYTNGAYGARAARTTYAAYTTYCARTCNCARATG YTNYTNAARTCNGCNYTNTCNYTNYTNATHTCNTTYGTNGTNTAYCAYGTNGCNGCNGTN TGYTTYGGNGCNCCNGTNYTNACNTCNGTNCARGARACNYTNCAYTTYGCNGCNYTNYTN ACNGTNATGGTNTCNYTNCCNTGYTGYYTNGTNGCNGGNCCNTCNATHGAYAAYTGGYTN GARGTNYTNYTNYTNCCNAAYACNAAYACNGGNYTNGARACNGTNGTNAARATHACNAGY ATHTGYGCNATHYTNGGNTCNTGGTTYGGNGCNGTNCCNATHCCNYTNGAYTGGGAYMGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNATGAARCCNAARAARYTNCAYGARGTNGGNYTNATGGCNMGNCAY GTNCAYMGNATHTGYATGGAYGCNAARTGYGAYACNGTNGTNGAYGTNGGNTCNGGNYTN GGNTAYYTNGAYCAYATHYTNCAYCARGCNTTYMGNYTNMGNGTNYTNGGNYTNGARGTN TGYCAYAGYCAYGCNTGYGCNGCNGARAARMGNGCNGGNATGCARGGNATHCAYTGYGGN GAYGTNMGNACNGTNCARTGYAGYATHGAYGAYACNGARGARAGYCARMGNCAYTTYGAR TCNGTNYTNGARGARGARACNCARGGNYTNCAYTGYTGYTGYTTYCAYAARATGGCN--- ---GTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNGARGGNACNTTYCARAAYTTYCCNGTN AGYCARGCNGGNCARCARGCNYTNMGNYTNCARGARCARCARAAYCARGGNCCNTTYYTN TCNCCNTCNAGYYTNMGNYTNGGNGCNCARGARACNMGNAGYMGNTGGMGNGTNCARAGY TCNTCNGAYCAYCARGAYCAYATGMGNCAYGTNGCNTTYMGNGGNYTNYTNGARATHACN GGNGARGARGCNTCNTCNATHMGNAARAARGTNMGNMGNAGYTGYTTYTCNAGYTTYGAR GCNTTYGTNGAYTCNTTYYTNGCN------CARGGNGGNGARGARGTNMGNMGNMGN--- ---GARYTNTGGGARYTNCAYGGNMGNCAYAARCAYMGNTTYGAYYTNATHGARCCNTTY ACNGCNYTNCARACNGTNGTNCARACNGTNGTNGARAGYYTNGTNTAYAARGAYMGNYTN YTNTGYYTNMGNGARAARGGNCAYACNTCNGCNAARATHGTNCCNATHTTYGAYGARACN ATHTCNCCNMGNAAYYTNGCNYTNATGGCNATHAARGAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TGG------------------------------------------ ------------------GTNCAYTGGGTNMGNAARTTY---------ATGTAYCCNMGN GAYTAYGTNTAYGTNMGNMGNTGYCARGTNGAYCARGAYACNAAYACNATGGTNATHTCN GCNMGNGCNACNGAYCAYCCNAGYTGYCCNYTNAAYTCNTCNCAYGTNMGNGTNGGNACN TAYACNTCNCARATGGTNATHTCNCCNGAYACNACNTTYGAYCARAAYGGNTTYCAYTAY YTNYTNACNTAYTGYGAYGAYCCNCARACNAAYTTYCCNACNGTNTGYTAYAARTGGATG GCNAGYACNGGNGTNTAYGAYTTYYTNGGNMGNGTNCAYACNGCNGCNYTNAARAARCAY GARATHGCNGTN---GARTTYTCNACNGCNCAYATGGAYAAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TAYYTNTGYYTNATHGTNTTYGTNMGNCARTAYMGNGARTAYGAR YTNAARAARGCNATHATHMGNYTNACNATHTCNYTNGTNGTNATHGCNYTNATHTTYACN TTYAARYTNYTNTCNTGYCARAARYTNGCNACNGGNGGNYTNACNTGYTCNGARGTNTTY GCNCCNGTNTTYGTNYTNYTNYTNATHYTNATGTTYMGNGCNTGYAARATGCAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GAYGAYGAYGAYGARGAYYTNTTYAARGGN GGNAGYACNGARATHAARYTNGARTCNGAYGARGARGGNAAYAGYAARGAYGARGARACN GAR---------------------------------------------------AARGCN AARGTNTCNAGYGAYTCNTCNGCNTCNTCNAARCCNCARATHTCNGTNTCNGARGCNATH ACNGCNAARACNAARGTNGCNGCNCCNTCNYTNAARACN---GARGARYTNAAYGAYACN YTNGARGARAARGARACNTTYGAYATHGAYATHAARATHACNGAYACNTGYAARATGGGN GAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYGAYATHCARGARATGGAYGGNCCNMGNCAYAARGCN YTNAARCAYGTNAARCCNAARATHTTYGAYGARAGYACNAGYTAYAAYAGYAGYGAYGAR YTNYTNTCNACNTTYAARYTNMGNGCNCARGGNCCNGTNACNAARGCNGCNMGNAARGCN MGNYTNACNTCNTTYAAYGCNMGNYTNAAYAARCARAARMGNAAYYTNGTNGCNAARAAY MGNAGYATHCCNCARACNTTYAGYGAYGAYGARYTNAAYTCNTCNGAYAGYGAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARTGYACNCAYGAYGGNTGYAAYCARGTNTTYGTNTTYCCNGGNMGNYTNAARMGNCAY ATGAARATHCAYCARGGNTAYCCNTGYGAYGTNGAYGGNTGYGGNGARATHYTNTCNAGY TGGTCNAARYTNMGNAGYCAYAARGCNTCNGCNCAYAGYCAYGARTTYGTNTGYMGNACN TGYGGNGCNAAYTTYAARACNAARTCNAAYYTNACNCARCAYATGAARATHCAYAARGGN GARYTNGARACNATHAARTGYCCNMGNGAYAAYTGYGARMGNACNTTYGCNTAYAARMGN AAYYTNATGCARCAYATHMGNTCNTTYCAYGAYGGNGARCARGTNTTYCCNGARAAR--- ------MGNATGAARACNAARGTNGCNAARCCNAARAARYTNCCNCARAARAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ---------MGNGARCAYYTNATHAAYACNGCNGTNAARTTYYTNCARAAYCCNAARGTN AGYTCNAGYCCNYTNTAYCARMGNAARGCNTTYYTNGARAARAARGGNYTNACNCARGAR GARATHAAYYTNGCNGTNCARMGNTCNGGNATHAARGAR------AAYGCNAAYCARGAR AAYAGYATHGTNCARAGYCAYCCNCCNGGNCAYCCNCCNGGNGCNYTN------GCNCCN GTNCARGGNACNCARCCNTTYTAYGCNCCNATHCCNCCNGARAGYATGTGGTCNAARGCN MGNAAYTGGACNATGGCNACNGTNGTNGTNGCNAGYGTNTCNTAYGCNATGTAYCARTTY TTY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYYTNAARYTNGTNAARTCNGARGCNGGNAAY TGYAARGTNACNGTNAARAARTCNATGTCNGGNTCNGTNGARTGGGCNAARYTNGARGAY AGYCARATGACNACNGTNGGNGAYTTYATHGAYMGNYTNGARAARGGNGTNACNTCNGAR TAYYTNTTYGAYTGGAGYYTNCCNYTNCAYTGYCCNCARYTNGCNAARYTNYTNAARATH CCNMGNTAYTTYTCNGGNAAYTTYYTNCARCARACNTCNCARGGNTCNYTNTAYCAYGAY AGYTGGCCNAGYYTNTTYGTNGCNCCNAARGGNGCNATHAGYAAYYTNCAYGTNGAYGCN TTYGCNTCNCAYTTYTGGATGATGYTNTTYGARGGNCAYAARMGNTGGACNYTNTTYGAY TCNGAYGAYACNGCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNMGNGARTAYCARAARYTNAAY CAYTAYCCNGGNTCNTTYCARATHGGNMGNAARGAYMGNYTNTGGMGN------------ ------------------------------------------------------------ ---CAYGARAAYGTNCCNAGYGCNMGNGGNGAYGTNGCNMGNGARGCNGAYGTNAAYCAR GTNGAYAAYYTNCCNGCNGCNGGNACNGCNCARAGYYTNMGNGCNAARTTYAGYAGYGGN GTNTCNGAYAAYGCNAAYCCNMGNTCNAARMGNGARATHACNCCNCCNAAYCCNACNCAR GGNGGNGGNGARTAYGTNTCNGARCCNMGNTCNTAYGTNGARMGNTAYGARGGNAARGCN GAYTCNGGNGTNTTYGARAGYCARCCNAGYTAYAAYGAYGARGTNGTNMGNGCNGAYTCN ACNCARGARGARGCNYTNCCNTCNCAYGGNACNGCNAARAAYATGGCNGCNMGNTTYAAR CARATGGGNCARTCNGGNTCNGCNCCNACNCCNGTNCCN---MGNGARATHACNCCNGAY MGN---TCNGGNMGNGTNGARTTYGTNTCNGARCCNMGNAGYCARATGGARCARTAYGAR GGNMGNGCNGARTCNGGNGTNTTYGARAGYCARCCNGARGARAAYCCNGAYGTNGTNMGN TCNGGNCARGARGTN---CARGARGARYTNCCNGARMGNGGNATGGCNAARAAYATGGCN AAYAARTTYMGNCARTTYAGYACNGAYGAYAAY------GCNGCNCCNMGNGCNAARMGN GCNATHACNCCNGAYACNTCNGGNMGNGGNGARTAYGTNAGYGARCCNMGNGGNCARGTN GARACNTAYCARAAYMGNACNGARTCNGGNGTNTTYGARAAYCARCCNGTNGARGAYCCN GARGTNGTNAARTCNGAYACNATGGGNGAYGAYTAYMGNCCNGARCARGGNTTYGCNMGN AAYGTNGCNGCNAARTTYMGNACNATGGARAAYTCNGCN------CCNCCNGTNTCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNGTNGCNCARGAYCAYCCNATHTTYATHGAY AARGARTAYAARGAYGGNGAYTGYAARATHYTNGARGGNCAYTTYTCNTCNCCNTTYATH CARCAYYTNCCNGGNGTNATGCCNAARGARGTNGARATHGCNMGNTTYCARGCNATHYTN CCNYTNCARTGGAARCAYCCNCARCAYAARCCNGTNTGYATHCAYYTNGCNGGNACNGGN GAYCAYTTYTTYTGGMGNMGNMGNYTNATHACNGCNAARCCNYTNATHAARGARGCNGGN ATGGCNTCNATHYTNYTNGARAAYCCNTAYTAYGGNTCNMGNAARCCNAARAARCARATG MGNTCNAGYYTNCAYAAYGTNAGYGAYYTNTTYGTNATGGGNGGNGCNYTNATHYTNGAR TCNATGGCNYTNYTNTAYTGGTGYGARMGNAAYGGNTGGGGNCCNYTNGGNATHTCNGGN ATHTCNATGGGNGGNCAYATGGCNTCNYTNGCNGCNACNAAYTGGAAYAARCCNATHTCN YTNATHCCNTGYYTNTCNTGGAGYACNGCNTCNTGYGTNTTYACNCAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TAYGCNAGYTCNAGYGAYTCNGAYACNGARCCNCCNYTNGTN GGNCARGCNTGGCARGAYAAYTGYGAYAGYGAYNNNGARAGYATHGAYAGYGAYCARGAR GAYATHYTNAARTAYGCNGGNGTNTAYACNACNGARGARGTNGCNCARATHYTNMGNGAY AARYTNATHMGNYTNCARTCNYTNTAYATHGAYCARTTYAARMGNYTNAARCAYGTNYTN YTNAARAARMGNMGNGARTGYYTNCARGCNTGYAARGCNGARGARGAYAARTTYGGNAGY ATHAARYTNTAYAARAARGAYCCNYTNGARMGNGAYAARTAYGARAARYTNTGYGCNATG AARMGNTAYAAYAARAARTCNGGNAARGARGCNYTNCARCARAARCARTCNACNCARMGN MGNATGCARTTYACNGARGGNYTNAAYTAYAARCCNCCNACNTTYCCNAARTGYATHTTY GTNGAYGAYGCNGTNMGNTGYAAYMGNMGNGTNGTNCCNYTNAGYAARTAYTGYCARAAR CAYATHATHCAYGAYCARAAYCARGTNYTNTAYAARCCNTGYCCNTTYGCNGAYGGNCAR TGYGGNMGNCCNGTNGCNACNYTNYTNGGNACNCARTTYTGYTCNYTNCAYCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNMGNGAY AARGTNMGNTGYYTNGAYGAYGARYTNTTYCARAARGARCARACNYTNAARAARTCNCAR GAYACNGTNGCNAGYYTNAAYMGNATGAAYACNTCNATGACNGARAARACNAAYGCNTTY GAYTGYYTNCARGARGAYTAYAGYMGNGCNCARGARATGATHACNAAYYTNGAYAARGAY GTNTCNGARYTNAARYTNTGYAAYCARGAYYTNCARMGNGAYATGGARTCNTGYAGYGAR MGNGARACNAARATGYTNGCNYTNCARTCNGARYTNAGYAARACNAAYGCNTTYYTNMGN TCNGARAAYACNACNYTNAGYAAYAARGCNTCNAAYYTNACNGGNGARGTNGARAARATG MGNATGGARYTNCARGARYTNGAYACNATHGTNAARGAYYTNAGYGAYAARTGYGARGAR GARAARAARAARMGNAARGARGARACNGAYMGNYTNCARGCNTCNYTNAAYGARAARYTN AARGARAAYAARGAYTTYAARCARAARTGGGARGAYGARGTNGAYAAYAAYAARACNYTN AARMGNMGNCAYGCNAAYAAYATHAARGAYYTNACNMGNCARYTNCAYCARGTNAARMGN MGNYTNGAYGTNGTNGAYGGN------GGNAAYAARGAYGGNAAYATGGGNTCNMGNTGY AAYTCNAGYAAYAGYYTNAAYTCNGTNGAY------AAYACNCAYCAYGGNCAYCARGGN CARCARGCNACNCARCARGARCAYCCNGTNATHACNGARCARGTNGARGTNGAYAARCAR GTNYTNATHGARMGNATHGTNMGNYTNCARAARGCNCAYGCNMGNAARAAYGARAARYTN GARTTYYTNGGNGARCAYATHCARCARYTNYTNGGNGARATHAARAARAARAAYAARATH ATHCARAGYTAYATHGTNMGNGARGARGCNGGNACNYTNTCNTCNGARGAYATGGAYGCN AAYAARYTNYTNGCNMGNAARGGNGGNATHATGGCNTCNGTNTAYTCNYTNCAYCARCAR CAYATGACNYTNGARYTNTCNYTNCARATHAAYAARAARYTNCARGCNGTNYTNGARGAY TGYYTNYTNAARAAYATHACNYTNAARGARAAYYTNGAYACNYTNGGNGARGARATHGCN MGNYTNTCNCARGARAAYMGNAARYTNCARYTNCAYYTNCARGARATHAGY--------- ------GGNGAYGARAGYTTYCARACNTTYATHYTNCAYGAYGARGAYCAYACNYTNGGN AAYGCNYTNAARTAYATHYTNAAYAARAAYCCNGAYGTNACNTTYGTNGGNTAYAGYATH ACNCAYCCNTCNGARAGYAAYATHAAYYTNMGNATHCARACNTCNGGNAARCCNGCNATG GAYATHYTNAARCARGGNTTYAARGAYYTNAARAARATGTGYAGYCAYATGYTNACNACN TTYGARTCNTCNGCNAARTAYTAYAARGARAAYCAY---GAYGARGARTCNCARATGGAY CARACNTGYACNAAYCARTCNTGYMGNAARCCNTTYYTNGTNATHGARMGNCCNCAYCAY TGYMGNMGNTGYGGNAGYGTNTTYTGYTCNACNTGYGTNCARTTYAARMGNMGNYTNAAY AARYTNGCNCAYYTNGAYCCNGAYGGNGAYYTNTAYAARGTNTGYAARAARTGYTTYGAY CARGAYAARTGYACNGARGGNCAYGTNMGNAAYYTNACNTCNGARTTYGTNGARYTNMGN TGGMGNTGYGARMGNYTNYTNCAYGGNTTYATGAAYAGYATHGGNAAYTCNGARYTNAAR ATGACNYTNCARGARGTNMGNAGYGTNGTNTCNACNCCNACNTGGATGAARTCNAGYYTN TGGYTNCARGARAAYATGTCNGGNAARTGYGGNGTNTGYCARGGNGCNTTYGGNYTNYTN AARAARAARGCNTTYTGYMGNGTNTGYGGNAAYGCNGTNTGYAARGCNTGYTCNAGYAAR GAYYTNYTNYTNTTYATHCCNGAYGARGGNCARMGNGTNAARATGGCNGTNATHMGNTTY GCNGGNTGYCCNGARGTNGARCCNGARGTNAGYYTNACNYTNMGNGTNTGYCCNTCNTGY AARGAYYTNYTNGTNCARMGNCARGCNCARTCNGTNGARGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ACN NNNGCNNNNTAYAAYAARTTYAAYAAYAAYTGYNNNNNNGAYTCNATHNNNYTNACNNNN NNNTGYGARGGNACNAGYNNNTTYGGNGGNTTYGCNATHTTYNNNGTNYTNGGNCAYATG GCNAAYGARGCNGGNGTNGAYATHGGNCAYTTYGCNAARTCNGGNGGNGCNAGYAARGGN CAYCAYCARAARAARCAYGAYMGNAARACNTCNCAYCAYAAYAARCAYCAYGGNGAYAAY GAYACNYTNTCNGARTCNAAYCCNCAYTAYAAYCAYAGYGARGCNGGNGCNGGNTGYGAR CARCAYGAYYTNTCNATGACNYTNGCNATGTGGGAYYTNGGNCAYTGYGAYCCNAARAAR TGYTCNGGNMGNAARYTNAGYMGNYTNGGNYTNGTNAAYACNYTNCAYYTNAARCARMGN TTYCCNGGNYTNATHYTNTCNCCNGTNGGNACNAARTGYGTNGCNCCNCARGAYMGNCCN ATHATHCARGAYCAYGGNATGGCNGTNATHGAYTGYAGYTGGGCNAARYTNGAYGARACN CCNTTYGCNAARATGAARGGNGAYCAYGCNMGNYTNYTNCCNTAYYTNATHGCNGCNAAY CCNATHAAYTAYGGNMGNCCNTGYAARYTNTCNTGYGCNGARGCNTTYGCNGCNACNYTN TTYATHACNGGNTTYACNGARGARGCNCARCAYGTNYTNTCNAARTTYAARTGGGGNCAY TCNTTYTAYACNYTNAAYMGNGARYTNYTNGARAGYTAYGCNTCNTGYGARACNAGY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TGYATGGCN------AGYAAYCCNGGNYTNYTNATGCARATH ATGGARCAYGGNAARGAYYTNAARTCNGCNGARCARGTNGAYTTYGCNTGYMGNAAYAAR GAYGGNYTNGCNAARGTNTTYGAYTGYGTNGARAARGARGTNATGAARTGYYTNCCNAAY GAYGTNGTNAAYTCNATHAARAARATHGTNCCNGGNYTNAARGARYTNACNGARGGNATG ACNTTYATGTGYGAYCAYAARGARGTNYTNGARAAYACNTGYYTNGAY---TCNAARATG CARGARATHYTNAAYTGYTAYATGGGNAARYTNACNAARYTNCAYTCNAARTTYGGNACN GCNAAYCCNGCNYTNGAYATHCARCARGTNYTNTGYAGYGTNATHACNGCNGARGARTCN TGYATHTCNCARCAYMGNGGNACNTGYAGYCARGARTAYATHGAYATHACNTTYGARATG ATHGAYAARATHTTYCCN---ACNAGYTGYCARCCNAGYYTNCCNAAYATHAARACNAAR GGNAAYGTNTTYGAYAGYATHYTNATHCAYGGNCARCCN--------------------- ---------------TGGTAYCARCCNMGNACNYTNTCNGARYTNYTNGAYYTNAARCAR AARTGYCCNGAYGCNAARYTNGTNCAYGGNAAYACNGARATHGGNGTNGARACNAARTTY AARAGYMGNCAYTAYCCNATHYTNATHTCNACNACNAAYATHCCNGARYTNTCNTCNYTN GTNGCNAAYCAYGAYGGNYTNGTNGTNGGNGCNTCNGTNACNYTNTCNCARYTNGAYGTN AARYTNAARGARYTNATHGGNTCNMGNMGNGARCAYGARACNMGNATHTTYCCNGCNATG TCNGARATGYTNAARYTNTTYGCNAGYACNCARATHMGNAAYGTNGCNTCNYTNAGYGGN AAYATHATGACNGCNAGYCCNATHTCNGAYGTNAAYCCNYTNYTNATHGCNGCNGGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNGAYTCNCCNGCNACNGTNTCNCARAARYTNCAYAGYYTNYTNCAR TCNYTNCCNAAYTTYGCNCCNGARYTNTCNCARTCNCARGGNTAYGTNMGNACNGGNTCN YTNMGNATHTAYMGNAGYTCNTCNYTNGAYTTYAGYCCNCARAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNAAYGARAAR AAYAARGTNGTNMGNTAYCARAARCARYTNCARYTNAAYTAYGTNCARATGCARMGNAAR AAYCARACNYTNGARACNGARGTNCARCARYTNACNYTNGARATGGARAAYMGNGAYATG AARYTNGTNGCNYTNAGYGGNGARGARAGYGTNTGY------------------------ ACNGCNTCNATHTTYAAYYTNGCNGTNYTNGTNTAYATGATHTAYTGGAARACNACNACN GARTCNYTNGTNCCNTAYTTYGTNGTNATGGGNYTNTGGGGNATGAGYGAYGGNATHTGG GTNGCNCARATHAAYAGYYTNYTNTGYGTNGTNTTYCCNGAYAARTTYGARGARGCNTTY GCNGGNYTNMGNATGTCNCARGGNATHGGNGTNGCNTTYGTNTTYGGNATHTCNGGNGTN TTYAGYATGYTNACNAARATHTAYATHYTNGGNGCNTCNTGYYTNATHGCNATGTTYTTY TAYATHYTNCAYGCNTAYTTYTTYMGN--------------------------------- ------------CAYGAYAGYACNCARYTNATGGCNTTYAAYAAYAAYYTNCAYGCNCCN CCNACNAAYACNGTNATHATHACNAAYGGNGGNMGNTAYGARGTNAAYGTNGGNCAYMGN YTNMGNYTNTCNGTNTAYTGGGAYGARGCNCCNACNCCNGTNMGNMGNTGYTCNTGGTTY TAYAARMGNGARGGNGAYAAYMGNTAYATHCCNTAYGARGARGAYTTYTGYGAYAARYTN GARAAYGARTAYAARAARGCNYTNGARACNGGNGGNTGGCAYMGNMGNYTNGARTTYCCN GGNAARGARATHATHGTNATGCAYAAYGCNAAYGTNATHGTNCAYTTYCCNGARAAYTCN CCNCCNGAYGARTGGGGNAAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MGNMGNTCNGGNTTYGCNCCNGTNAARCCNGAR TTYATHATHCAYGAYCAYAARCCNAARYTNCARACNGARTTYYTNAGYGCNGAYGTNAAR CARGARYTN---------YTNTCNAARGAYGARGCNGCNGTNGAYAARGTNGCNAGYGAR GARCARCARGCNGARGARGAY------GARCCNCCNCARAARAARGTNAARYTNACNGGN MGNAAYAARAARMGNCCNMGNAAYGARAARATHCARGCNAARGAYMGNATHTGYCCNGCN ATHAARTCNGGNAARGARTGYAARTTYGGNGARMGNTGYAARTTYAAYCAYAAYATHGAR GARTTYYTNGARCARAARATGCCNGAYYTNGAYMGNCCNTGYYTNYTNTTYGARACNTTY GGNTTYTGYAARTAYGGNGTNGCNTGYMGNTTYGCNAARAGYCAYYTNAAYGARAARAAY GARAAYGTNATHAAYCARGARYTNTAYGARAARATGGGNAGYAARATGGGNCCNYTNAAY ACNYTNAARGARGARGTNMGNCAYAARYTNTGGAARMGNMGNTAYAAYTTYAARAARGCN GAYACNGTNGTNAARGARGTNCARAARACNTTYMGNGGNGAYGARAGYAARGARGARGAY GGNYTNGTNGTNAARGTNGARACNGARTCNGARACNACNACNGAYGTNGAYGCNGCNGTN AARACNGARAAYGGNAGYGGNAGY------------ACNCCNATHGCNCCNTCNAAYATG CAYGTNGARACNGTNAAYCARAARACNTCNYTNGGNAGYGCNAGYGGNGTNGARGAYGCN GTNAARATGGARAAYAAY---------------------------------------GTN AARACNTTYGGNCCNATHACNGAYGARGARGTNACNTCNYTNMGNCCNGGNGARMGNAAR AARGTNGAYTTYMGNAAYAARYTNTAYYTNGCNCCNYTNACNACNGTNGGNAAYYTNCCN TTYMGNMGNYTNTGYAARGGNTTYGGNGTNGAYATHACNTGYGGNGARATGGCNGTNGCN TCNCARYTNYTNAARGGNAARCARTCNGARTGGTCNYTNATHAARMGNCAYCCNTGYGAR GAYGTNTTYGGNGTNCARYTNTGYGGNTCNTAYCCNGAYTCNATGACNMGNTGYGCNCAR YTNYTNGTNGARTCNTCNGAYGTNGAYTTYATHGAYATHAAYTGYGGNTGYCCNATHGAY YTNATHTTYAARAARGGNTGYGGNTGYGCNYTNATGGGNAARGCNACNAARYTNGARCAR ATHTCNMGNAGYATGYTNGGNGTNATGGGNGAYACNCCNYTNACNGTNAARATHMGNACN GGNATHYTNGAYCAYAARAAYGTNGCNCAYACNYTNATHCCNMGNYTNMGNGAYGCNGGN GTNTCNYTNATGACNYTNCAYGGNMGNTCNMGNGARCARMGNTAYACNMGNYTNGCNGAY TGGGAYTAYATHTCNCARTGYTCNGCNGCNGGNAGYCCNATGCCNGTNTTYGGNAAYGGN GAYGTNYTNTCNTAYGARGAYGCNAAYTAYCAYATGGARAARAAYAAYGTNTCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGAGYAAYCARTGYAARCAR ACNGARTGGATHYTNGARACNATHGAYCAYYTNMGNMGNMGNAARGCNMGNCCNGAYYTN CARMGNATHTGYCAYGTNGTNAARMGNMGNTTYGGNYTNAGYGCNACNGAYACNGARGCN AARYTNGARAARYTNGTNGAYGCNGARGTNGTNATHAARGTNGAYTAYAARGGNAAYACN AGYTAYMGNAAYGCNGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGAARCCNCARMGNGGNAARTCNMGNMGNMGNAAYGCNAAYTCNCCNYTN CARGARCCNGTNGCNGTNTAYTGYMGNATHMGNCCNCCNGAYGAYCCNAAYGAYGTNYTN TGYGCNAARCCNYTNAGYGARACNGTNGTNCARYTNGTNCCNGGNGARAAYTCNACNGGN MGNAAYGGNCARGTNAARGARYTNCARTAYACNTTYAGYCAYGTNTTYGAYTAYTGYTCN TCNCARAARGGNATHTTYGAYCAYGTNGCNYTNCCNYTNGTNGARGAYYTNATHGCNGGN AARAAYGGNYTNYTNTTYACNTAYGGNATHACNGGNTCNGGNAARACNTAYACNATGACN GGNAGYCCNCARGAYCARGGNATHYTNCCNMGNTGYYTNGAYGTNGTNTTYAAYAGYATH GTNGGNMGNCARGCNAARAARTAYGTNTTYAARCCNGAYMGNATGAAYGGNTTYGARGTN CARACNGARGTNGAYGCNATGATGGARMGNCARAARAARGARATHATHCCNAAYYTNACN ACNCCNAGYAARACNCCNATGAARMGNCARGARTCNGCNGAYATHGARMGNYTNACNGAY CCNACNGTNGTNGAYACNGTNGAYGAYGAYAAYAAYTAYTCNGTNTTYGTNTCNTAYATH GARATHTAYAAYAAYTAYGTNTAYGAYYTNYTNGARGAYYTNCCNTAYAAYACNATHACN GGNTAYAARCCNCCNCARACNAARATHYTNMGNACNGAYYTNGCNGAYAAYATGTAYGTN CAYAAYTGYACNGARGTNGARGTNAARCARCCNCARGAYGCNATHGAYGTNTTYTAYAAR GGNCARMGNMGNMGNAARGTNGCNCAYACNGCNYTNAAYGCNGARTCNAGYMGNAGYCAY AGYGTNTTYAAYATHMGNYTNGTNCARGCNCCNYTNGAYGAYAARGGNGARGARGTNYTN CARGAYACNAAYMGNATHTGYGTNTCNCARYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATHTCNAARYTNCARTCNGARYTNAAYGARTCNAAYAGYAARATHAGYACNYTNAAYAAR GARYTNTCNAARGCNMGNAAYATHATHGARTGYCAYGARGCNGGNATHGTNYTNYTNAAY GARAARTCNGAYGAYCARMGNMGNAAYYTNAGYCARGCNGARACNGAYAARGGNMGNCAY GARAGYACNATHGCNGTNYTNMGNCARAGYTCNGTNGAYAARGARCARYTNATHGTNACN YTNCARGGNCARYTNAAYCAYATGACNTCNYTNYTNAAYCCNAGYCARATGMGNCARYTN CARTCNAGYAARCCNAGYTCNAAYYTNCCNGARYTNGARTTYGTNGARCARAARGCNATH GAYTAYTAYCCNCARGARACNATGACNAAR---------------CARGARGGNACNYTN YTNAARTCNAGYCCNMGNYTNAARGARGAYGARGARATGGARGARGAYAGY--------- ------------GTNYTNAARAARGARYTNGAYGAYYTNCARATHMGNYTNAAYGARAAR GAYATHGTNGTNGCNGARYTNCARAARTCNAAYTCNACNYTNYTNTCNATGYTNGAR--- AARGGN---GCNGGNGGNGAYCARACNGAYCARYTNTCNGCNCAYAARATGGARTCNGAR YTNMGNAAYYTNMGNGCNGARAARGARCARATHGTNGCNGTNGTNAAYGARAARTCNMGN GARAAYTCNTTYYTNAARTCNGARGTNCAYCAYYTNATGGARGTNGTNTCNGCNGGNCAR GCNGCNATHAAYAARYTNCARCARGAYATHYTNACNYTNGARCARCARCARCARCARCAR ACNCCNCCNGGNGGNGARGAYGARGAYGARATGMGNMGNGARGCNYTNGCNAAYATGGCN AARYTNGTNMGNGAYMGNGARCARGARATHGARGCNYTNAARCARAARAAYGARACNYTN GTNYTNTTYYTNCARGAR---TCNAGYGARTCNGARGCNGCNGCNCAYYTNGGNCCNYTN YTNMGNGARAARGAYACNYTNTCNCARMGNATGGCNGARATGAGYGCNGARMGNGARCAR YTNATHGCNTGYGTNACNCARAARCAYAAYGARTCNYTNGCNTAYCAYGCNGARGTNCAR MGNYTNACNGCNATHYTNGTNGAYTCNCARCARATHTCNGARAARACNAARTCNGARTAY TCNGTNYTNGTNACNCARTTYGARGAYAARACNCARGCNYTNATGTCNGCNCARTCNGAR YTNATHGARTGYAARCARAARYTNAARGARYTNGARATHMGNCAYGGNGARYTNATHCAR MGNTCNAGYYTNCARCARAGYTCNYTNCCNGCNTCNGAYYTNGAYYTNGARATG------ ------------------GAYCAYYTNAARCARYTNGARTCNGAYYTNAARTCNGCNGTN GGNCARMGNGAYGARMGNATHCARGCNYTNYTNCARAARACNAGYGCNYTNGARGARMGN ATHGCNTCNAARGAYTCNGARTGYGCNCAYYTNAARAARCARGTNGARAAYACNAARTTY CARYTNACNAGYTTYATGGCNGARATHGCNGAYGTNAARACNGARMGNGARCAYGCNCAR GARAARTAYATGTCNGARACNYTNGARTGYAGYGGNYTNMGNGARACNGTNAAYCARYTN ACNYTNGCNTCNAARGARAARGARYTNGARGTNTCNTCNYTNAARGAYCARGTNACNAGY YTNAAYTCNYTNYTNCARGAYAARCARGGNGAR---AGYCARYTNTCNCARYTNATGCAY GARAARGAYGTNGCNYTNGCNAAYMGNMGNCARYTNCARCARGARGCNGAYCARAAYAAR ATHGTNGCNGARCARMGNYTNCARGARTGYGCNGCNYTNAARAARCARATHTCNGAYYTN AAYGARMGNGARTTYAARYTNAGYMGNGARGTNAAYMGNYTNMGNGCNCAYYTNATHGAR GTNGARGAYGGNTAYACNAARGARGCNYTNGARTCNGARGARMGNGARAARGARYTNMGN AAYMGNYTNTCNAARGCNGARGARCARYTNGTNTCNTCNTCNTCNGARGTNGARYTNGCN AGYAARGARTCNGTNMGNCARATHGARAAYYTNGARCARCARYTNCARCAYATHGCNAGY CARMGNGAYGCNGCNTAYATGCARATHTCNACNATHCARGARCARTGYCARCARTAYGCN TCNTCNYTNAGYAAYYTNCARYTNGTNYTNGARCAYTTYCARAARGARAARGAYTCNGCN ATHTCNYTNGARACNGARMGNTAYCARGARCAYGTNAARTCNYTNAGYAGYAARGTNGAR GARMGNACNACNGARYTNGAYGCNACNMGNGCNGAYYTNAARGARGCNYTNGAYGCNYTN GAYGCNGCNTCNMGNATHAGYGARCARYTNGAYMGNAARGAYGARGCNYTNGCNGCNYTN AARGGNGARGTNCARYTNMGNGARGAYGCNYTNGCNGCNGCNGARGARGARATHCAYTCN YTNAAYAGYAGYACNGARGCNAARGTNNNNAARACNYTNATGCAYAAYGTNGTNATGACN TGGYTNACNTCNCCNGARAARAARMGNCCNGARATHGTNCARYTNATHGGNCAYATHYTN AGYTTYAGYTCNGAYGARTTYAARAARATHGAYGCNGCNCARAAYCARGGNGGNACNTGG ATHGGNTTYTTYAARMGNTCNCCNGARGARTCNGCNACNTCNGCNCCNTCN------CCN CARTCNTTYTCNCARYTNTTYGTNAARTTYYTNGARAARGARTCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TGY TTYGTNCAYMGNAARMGNTGYTCNTAYACNTTYGARTCNGGNGARYTNATGTGYCAYTCN AAYAARCCNGGNCARTTYGCNTGYTGYYTNGGNGAYYTNTGYAAYAARGGNYTNATGCCN TCNACNCCNMGNCCNCCNGCNYTNGTNGCNGARAARGARACNTCNAGYYTNTCNTTYATH YTNATHGTNGCNGTNTCNGTNGTNYTNYTNYTNGCNATHGCNYTNTTYTTY--------- ---ATHMGNMGNCAYATHTAYAARMGNMGNGARGAYAGYYTNYTNACNCCNGAYGCNMGN YTNYTNGARGARGAYATHTTYGGN---GGNYTNMGNCARGARCARTCNTCNACNGGNAGY GGNTCNGGNATGCCNAAYYTNGTNCCNMGNACNGTNGGNAARCARGTNACNYTNATHGAR AARATHGGNAARGGNMGNTTYGGNGARGTNTGGMGNGGNAARTGGCARGAYGARGAYGTN GCNGTNAARATHTTYACNTCNYTNGARGARACNAGYTGGAARCARGARATGGGNATHTAY AAYACNGGNATGYTNMGNCAYGARAAYATHYTNGGNTTYTAYGCNTCNGAYACNATHGGN ATHTTYTCNTGYACNAARAAYYTNYTNATHGTNCAYTAYCAYCCNTAYGGNTCNYTNTAY GAYTAYYTNCARATGAGYGAYATHGAYATGGARGAYATGYTNAAYYTNAGYCAYTCNGCN GCNGCNGGNYTNAAYCAYYTNCAYTAYGARATHAARCARGGNACNGGNATGCAYGARAAR CCNTCNATHGCNCAYMGNGAYATHAARTCNAARAAYATHYTNGTNAARGCNAAYGGNGAR TGYTGYATHGGNGAYYTNGGNCAYGCNGTNAARAAYACNGCNAGYTGGGAYCCNGGNMGN GAYAARYTNYTNGTNGGNACNAARMGNTAYATGGCNCCNGARGTNYTNACNAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGYTNTTYGAYATHMGNGAYTGGMGNCARGGNGTNTCNYTNYTNTGYGAYGAYYTNCAY MGNAARYTNGTNTTYAGYMGNCAYTTYGAYTGYYTNCAYCCNTAYGCNCCNYTNATHTTY AAYTGYATHCARAARCARACNMGNCAYTTYAARMGNGCNGTNACNAAYGCNGGNYTNGTN CCNTAYAAYGTNYTNCAYGAYATHACNTGYAAYTTYGCNGARAAYGTNGTNACNTGYYTN GGNGAYCCNGTNTCNMGNTCNTGYCCNCARGARGTNGTNTAYACNYTNGTNTCNGCNYTN CAYMGNTTYYTNCCNCCNGCNTGYGCNCCNGTNCCNGCNGTNGCNMGNATGCARGARGGN AARGGN------CARGGNMGNGAYCARCCNACNGTNYTNGARACNGTNATHYTNGARGGN GGNGARGGNATGGCNGAYTCNGGNATHGAYGTNGAYYTNGTNAGYTCNMGNAAYGTNGAY GARGAYCCNGAYCARGAYAAYATGAAYTAYTAYGARYTNACNAGYAARGTNGTNGTNGGN AGYCCNGCNACNGARATHAARCAYGCNAGYATGCCNATGMGNGCNAAYYTNAARCARCAR YTNATGAARCARCARYTNMGNGAYCARGARAARMGNGAYCARTTYTCNAARAAYGGNTCN TAYATHACNGGNTCNGCNGGNATHAAYGTNCCNMGNGTNGTNGARACN---GARGTNCCN ACNAAYGTNYTNCAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNMGNMGN GTNGCNTGGMGNCAYYTNYTNAAYATHTTYCCNGCNAAYATGTCNGGNMGNGAYMGNTTY GAYTAYATGAARMGNAARGARGARGARTAYMGNAAYYTNMGNGAYGARTGGMGNGARMGN TTYMGNACNAAYAAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GAYYTNAAYAARATHMGNTTYGCN GCNTAYMGNACNGGNATGAARYTNMGNATGYTNCARAARAARYTNTGYYTNGAYGTNGTN AGYYTNGGNCARGCNAGYGAYGCNTTYGAYCARCAYGGNYTNMGNGGNMGNAAYGAYAAR YTNYTNGAYGTNGGNGARATGATHGARTGYYTNTCNACNGTNTTYGARGGNGCNGCNAGY CARCAYCCNGAYYTNGTNAAYGTNGCNYTNGCNYTNGAYYTNACNYTNAAYTGGATHYTN GAYGTNTAYGAYAGYGTNMGNAGYGGNAARGTNMGNGTNYTNTCNTTYAARGTNGGNYTN GTNYTNYTNTGYCARGCNCARYTNGARGAYAARTAYMGNTTYATGTTYMGNYTNATHGCN GAYATHAAYGCNTTYGCNGAYCARMGNAARYTNGGNYTNYTNYTNCAYGAYTGYATGCAR GTNCCNMGNCARYTNGGNGARATHGCNTCNTTYGGNGGNAGYAAYATHGARCCNAGYGTN MGNAGYTGYTTYGARAARGCNAAYGGNMGNCCNGARATHGARGCNTCNCAYTTYYTNGAY TGGYTNAARYTNGARCCNCARTCNYTNGTNTGGYTNCCNGTNYTNCAYMGNYTNGCNGCN GCNGARACNGCNAARCAYCARGCNAARTGYAAYGTNTGYAARGGNTTYCCNATHATHGGN TTYMGNTAYMGNTGYYTNAARTGYTTYAAYTTYGAYGTNTGYCARCAYTGYTTYTTYTCN GGNMGNACNGCNAARAGYCAYAARYTNACNCAYCCNATGCARGARTAYTGYACNGCNACN ACNTCNGGNGARGAYGTNMGNGAYTTYTCNAARGTNTTYAARAAYAARTTYAARTCNAAR MGNCAYTTYAARAARCAYCCNMGNMGNGGNTAYYTNCCNGTNGAYGCNCAYYTNGARGGN GAYTCNYTNGARAGYCCNAAYCCNTCNCCNCARCAYAGYATHTCNCARGAYATGCAYTCN MGNYTNGARATGYTNACNAGYMGNATHGCNGARGTNGARCARMGNCARGGNGGNTCNTCN GAYYTNGARGAYGARCAYCARYTNATHGCNCAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CCNGTNACNCCNMGNATHGAYMGN GCNATGCARTAYYTNCARACNTGGACNACNGAYMGNGGNTCNTGGAARTTYAAYAARATG YTNCARGTNCAYYTNYTNCARGTNATGTAYGAYGGNACNAARATGAGYGAYGAYGAYTAY AAYATGYTNYTNCCNTAYYTNGARGGNATGGGNGCNTCNGCNAARAARMGNACNATHGAR GARGCNATGAARATHTCNACNGAYGARTCNGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARGAYAARACNAAYGCNACNTCNCARTGYAARMGNYTNTAYGAYGARATG CARGCNTCNTAYAGYCARMGNGARMGNTCNATHCARMGNTGYYTNCARATGGTNAAYAAR GAYATHAARGAYYTNMGNGCNAARAARGARGGNGAYCCNGAYAAYTTYGAYGTNATHAAR TCNYTNMGNAARGARCARACNAARYTNMGNYTNATGCARCARGARATGAGYGTNGARGAR GTNGTNAARGAYMGNACNYTNAARGTN--------------------------------- ------------------------------------------GGNCAYGGNCCNYTNTCN CAYTTYTTYGAYGGNMGNTTYATGCCNAARCAYCCNGCNAAR---GARTGGAARCAYGAR GAYTTYTCNGTNGCNATHTTYGARMGNATHGCNGGNAARYTNGGNAAYGARTTYGAY--- ------------AARTAYGGNYTN---MGNGAYAARYTNAAYTTYATHAARTGYATHATH GGNGGNCCNGAYTGYGCN------GGNGAYCAYATHGTNGAYGGN---------GCNAAR AARTTYYTNTAYCARATHGTNGCNAAYAARGARAGYGGNTTYGAYGTNGAYAARTTYGAY TAYYTNGCNMGNGAYAGYYTNCAYYTNAAYYTNCCNAGYTCNTTYGAYCARATGMGNYTN YTNCAYTTYATHMGNGTNTGYGARTTYGARGGNGARMGNTGYYTNTGYYTNMGNGAYAAR GARGCNGGNAAYYTNTAYCARATGTAYTAYAAYMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARTTYAARGARTAYGARATGGARAARGARTTY CARAARAAYGARCAYYTNCARGARYTNCCNGARGARGARMGNAARAARGARGARGCNAAR YTNGARYTNYTNAARAARCARCAYMGNGAYCAYCCNAARYTNAAYCAYCCNGGNAGYMGN GAYCARATGGARGARGTNTGGAAYACNAARGAYCARYTNGARGAYCARCARTTYGAYCCN AARGTNTTYTTYATGAARCAYGAYYTNGAYAGYGAYGGNGARTGGAAYYTNCCNGARGTN GARGCNATHYTNYTNCCNGARATHGARAARGTNTTYGAYGARAARAAYTCNCCNGARGAR GAYGAYCCNATHGARMGNCARGARGARYTNGCNMGNATGMGNGARCAYGTNTTYTCNGAR ATHGAYAARGAYCAYTCNTTYACNATHACNYTNGAYGARTTYATGACNTAYGCNGGNACN CAYGGNGARAARGARGARTTYAARGARTAYGAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGACNACNTTYGGNYTNCAYYTNGGNAAYTGY TCNGCNTGYYTNGCNTTYCAYMGNGAYGGNAARACNGAYGTNGTNGCNAAYGAYYTNGGN GAYMGNGTNACNCCNGCNGTNGTNGCNTTYACNGAYCAYGARATHTCNGTNGGNGCNGCN GCNAARCARGGNATHACNMGNAAYGCNAARAAYACNGTNTGYAAYGTNAARCARATHYTN GGNCAYMGNATHAARGAYGARCARGTNCARGCNTAYATGAARAAYAAYTCNGTNATHGTN GARAAYCARGARGGNYTNCCNGTNTTYTGYGTNGARCAYAARGGNAARCARTCNMGNTTY ACNCCNGARMGNGTNGTNGARTTYYTNTAYCARAARATGYTNGARACNGCNCARAGYYTN GGNGGNAGYGGNAAYCARAARGTNGTNYTNGCNATHCCNGCNGGNTTYACNGARGARCAR MGNTCNATHGTNAGYGARGCNGCNACNAARGTNGGNTTYAAYATHYTNMGNYTNATHAAY GARTCNTCNGCNGCNATGYTNGCNTAYGAYATHGGNCARYTNGAYCARTCNGARCAY--- TTYAARACNYTNATHTAYMGNYTNGGNGGNACNTCNCAYGAYGCNACNYTNGTNGARACN ATHCAYGGNATGTAYMGNATHATHTCNMGNGTNGAYGAYACNACNTTYGGNGCNGAYAAR TTYACNGARGTNATGCARGGNTTYYTNGCNAAYGARTTYAARMGNCARAAYMGNTGYGAY ATGACNGARAAYAARMGNTCNGTNAGYAARYTNCAYYTNGCNTCNGARGGNTGYAARACN GCNYTNTCNACNATGATHAGYGCNTCNTGYGAYGTNGARTCNYTNTTYGAYGGNTGYGAY TTYCAYTGYAAYGTNTCNMGNGCNMGNTTYGARATGYTNATHCARCCNYTNATGTCNAAY TGYACNCARYTNATHGARAARYTNYTNGARCARGCNGGNTGYAGYAARGGNGAYGTNGCN AARGTNATHGTNTGYGGNGGNGGNGCNAARCCNCCNTTYGTNAARAARATHATHGGNGAY TTYYTNCCNTCNTCNACNYTNYTNAAYTCNATHAGYGARGAYGARGTNATHGCNGTNGGN GCNGCNAARGARGCNGCNYTNYTNGTNGGNGAYGGNAARGCNGGNGCNAGYYTNGAYAAR CARTCNACNGTNAGYTTYAAYACNYTNCCNAARGCNGTNGGNATHMGNATGAGYCCNACN GARTCNGARGTNATHYTNCCNCARCAYAGYYTNGCNCCNATGMGNMGNCARCAYACNTAY AGYYTNCCNTCNGCNCARACNCAYTTYGCNATGGARYTNYTNCARATGGARGAR---GCN AAYCARCARGAR---GCNCCNGTNATHGCNMGNGTNGTNYTNAARGAYYTNCCNCARGGN TCNACNGTNAARTCNAGYTTYCAYYTNMGNMGN--------------------------- ------------------------------------------------------------ ------------------------TAYTAYTAYGAYGCNGTNAAYAAYGTNTCNMGNACN GAYCAYGGNAARGGNCARTAYGAYGARATGTGYMGNAGYATHATHGGNAARGARTTYAGY GAYGARGCN---TGYTCNTTYTTYGTNGCNYTNGAYGGNTGGMGNTAYYTNTAYTTYCCN GCNGAYAARTCNTGYTGYAARTAYTGYAAYAARACNGARGGNTGYGGNATHATHAARAAR AAYTGGYTN---GAYGGNGCNACNTAYCARGGNCARYTNACNACNGARGGNCAYGTNTGY AAYGGNTGGYTNAARATGGGNGGNGARCARAAYTTYTAYTAYGCNACNGCNGAYGCNGCN CARCARCCNTGYYTNTAYTAYGARACNYTNCARMGNGGNATHAAYATGTGGAAYTAYTCN TTYACNGARTAYATHGTNGGNAARCARGAYCCNTCNYTNTTYCARCCNTGGCCNTCNTGY GAYAARCCNTGY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GAYGAYGAYGARGAYGAYGARGAY TCN------------------------------------GGNGARMGNGGNGAYGAYGCN GARTCNMGNACNAGYGGNAAYACNGTNGARTCNGAYGGNGGNYTNTCNGCNGARGTNCCN ACNGTNACNGTNCAYYTNGGNTCNAAYATGGAYGTNGAYATHGAYGGNAGYGARAGYMGN TCNGCNTCNCCNAARAARGTNMGNTTYGARGAYTCNAGYGCNGCNTAYACNAAYATHAAR CCNGTNACNCAYGARAARGAYACNTGGACNGGNCARGARGAYTAYGAYMGNTCNYTNTTY ATHMGNATHTTYTGYCCNGARGGNYTNGAYGAR---GARACNGAYYTNAARTGYTCNYTN TCNTAYGARGGNAAYATGTTYAARACNCCNATHYTNGAYATGCCNGARGAYYTNCCNTCN GAYGARAGYYTNCCNGAYGCNGARGAYGCNMGNCCNAGYAARMGNCCNCARGCNGCNMGN AARTCNGAYGARMGNYTNAAYCCNACNGARACNCCNGTNCCNTCNAGYTCN------AAR CAYAARAARTAYTTYGARTTYGARATHCCNYTNCCNGARGARATHAARCCNGGNGTNGTN YTNTTYGGNGARAARCCNCCNCCNGARCCNGARAAYATHCARGTNGCNGTNYTNGCNGGN CARTTYGARGARATHGTNGCNYTNGCNACNATHGAYTTYGARGAYATHAARGARYTNAGY YTNGARACNGTNYTNYTNCCNGGNCCNACNGGNGAYGAYGAYGTN---ACNCCNAARTCN MGNGCNAGYTCNGCNAGYGCNGCNTCNAGYYTNGGNGGNGARTCNYTNTCNGAYTCNATG GAYATHCCNATHATGYTNGAYGAYACNGCNGARCAR------------YTNCCNGCNTCN ACNCCNCARGARGAYYTNYTNAARGARAGYCARCCNGTNCCNTTYCCNYTNTAYYTNYTN CAYGGNGGNAARACNGAYTCNYTNCAYATHCCNTGYGGNAAYGTNCCNYTNYTNATGTAY TGGGGNAARMGNCCNMGNCCNYTNAAYTTYAAYMGNCARTGYGGNACNYTNGGNATHTAY GAYATHGTNTAYGAYATHACNGGNTAYGAYATGTCNACNATGACNAARGAYGAYYTNCAY AARGARATGGTNGAYGARGCNYTNTCNGTNGTNGCNTTYACNCCNGARGTNACNACNGCN GAYAARTCNACNAGYATHGARGARACNGTNCCNAARTCNCARTAYGAYAAYYTNGTNGAR CARCAYCARGARGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GGNAGYGTNTAY TCNYTNACNAGYTAYAGYGAYTGYACNGAYAARYTNCAYAAYATHTAYAGYMGNGARGCN ACNGTNYTNGGNCAYGAYATHTCNTCNTCNGAYMGNGGNCCNMGNCAYTGYACNGTNAAR YTNTTYTCNCARACNCARTTYGGNCARGTNAARYTNTCNATHAAYATHGTNTCNATGAAY ATHGARGAYCCNAGYACNATHYTNTCNATHTAYGAYGGNCARGGNTCNGGNYTNYTNGCN TCNTTYAGYTCNGGNAGYTCNACNAAYTTYAAYMGNTAYAAYYTNATGACNTCNGGNGAY ACNGTNACNTTYATHYTNGARMGNCARGAY---GARAAYYTNAAYTTYGAYATHCARGTN AARGTNAARCCNATHCCNAGYAAYACNGARCCNGGNTAYGARAAYAAYTTYGGNGGNGAY ---TAYTTYGAYAARTTYTCNCARCCNACNATHGTNGCNYTNATHGGNAGYTTYTAYGCN GCNGTNYTNATHGTNTGYATHATHATHYTNATHTGYGAYTGYYTNMGNTCNAARGGNGAR CARAARMGNTGGGARACNGTNGARYTNTCNACNATGMGNTCNMGNCCNGCNYTNGAYAGY MGNAGYCAYGTNACNCAYTCNTCNAAYGGNTGGTCNTCNGAYCARCAYAARGARMGNCCN CCNGCNAGYCARTAYTCNGTNGAY------AARCCNTAYACNMGNAAYMGNMGNCCNCCN ---AGYGARGARGAR------------TAYGAYCAYGAYGAYMGNGTNCARCARCAYGAY YTNATGAARGARGARMGNGARMGNGARAAR---GCNMGNCAYMGNATGGCNAAYCAYAAY GCNTCNTAYGCNGAYCARGAYAAYGCNGAYCAYTTYAARGARAARGTNGTNACNCCNMGN GTNAARGCNAAYYTNMGNMGNAGYCAYAARCCNCCNACNTAYGCNGARGCNGTNAGYGAY CAYTCNTCNACNCARTCNTCNGARGARGAYGAYTCNGARGCNTCNAGYTCNCAYMGNTCN ACNMGNAARMGNCCNGCNTCNTCNMGNTCNMGNTCNACNMGNTCNTCNAARTCNTAYTCN ACNTCNGCNTCNGARTCNGARGARAGYGARAGYGARGARGAYTCNMGNMGNGGNGGNGCN AARGGNMGNMGNCCNAARGGNAARCCNAARGARAARMGNMGNCCNMGNMGN--------- ------------MGNMGNCAYTCNAGYGAYGARTCNGGNCCNTCNMGNMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AAYTCNATHGTNTGYCCNACNTGYGAYCARAARACNACNYTNCCNGARAARGGNGTNCAY GGNYTNCARTCNGAYATGGTNYTNGARAAYATGATHGARGCNGAYTCNGAYGARGCNAAR CARATHGARTGYACNAGYTGYAARGCNGGNGAYAAYGCNGTNGCNMGNTGYMGNACNTGY GARAAYYTNYTNTGYCCNAAYTGYGTNACNGCNCAYCARTTYATGMGNTGYTTYGARGAY CAYCARGTNGTNACNTTYGARGAYATGATHAGYAGYGGNGARGGNATHGARCAYYTNMGN MGNCCNATHTTYTGYAGYGCNCAYAGYGTNGARACNATHAARTTYTTYTGYAGYAAYTGY ATGATGTGYAAYGARTGYGTNCARAARTCNCAYAGYGGNCCNGARCAYGCNATGAARCAR YTNTCNGAYTCNGTNACNTCNAAYAARGARACNYTNATGAGYTAYACNGCNGARTGYGGN AARAARYTNGARGARTGYCARAARAARAAYTCNACNYTNACNTCNAAYTTYGARGARYTN GARATHCARAARGAYAGYACNAARGGNYTNATHGARGARACNTTYCARAGYTAYAARGCN ATHYTNGARGARACNMGNGAYTCNTTYYTNAARGAYYTNGAYGAYYTNCAYAARAARMGN GARYTNAGYYTNATGGARAGYATGGARAARYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CARAARACNAGYTTYAARATHGTNACNTCNAAR GARCAYMGNTTYCARMGNACNGCNAAYGCNYTNCAYAARTCNGGNYTNTGGGARGTNGCN ATGAARACNGGNAAYYTNATGAARMGNAAYMGNGARYTNCARAARGARYTNGARGAYTTY MGNTCNGAYGCNYTNACNTTYYTNAARTCNGTNATHAARAAYCCNCARAAYMGNGGNTTY ATHAARAGYGTNYTNAAYAAYGCNYTN--------------------------------- ------------------------ATGCCNCCNCCNAAYMGNTGGGAYGCNTAYATHCCN YTNGGNAARATHATHCARGGNACNAARTTYATHGCNTTYAARGTNCCNYTNAARGARGCN YTNATGACNGCNGTNGARGAYATHCARAARTTYTCNCCNTCNATHYTNAARGARMGNYTN AAYGARYTNGGNATHAARATGGGNYTNATHATHGAYYTNACNAAYACNMGNAARTAYTAY AAYGARACNGARTTYACNGAYCAYGAYATHGARTAYAARAARATHTTYACNCARGGNCAY ATGGTNCCNGGNGAYAGYGARTTYCARAAYTTYGCNGARGCNGTNCAYMGNTTYAAYAAR AARGAYCARGTNATHGGNGTNCAYTGYACNCAYGGNGTNAAYMGNACNGGNTAYATGATH TGYMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGGGNAGYGTNACNGTNTGGMGN GGNYTNYTNTTYYTNYTNYTNGCNGCNAGYACNGCNAAYMGNMGNCARTCNGGNTTYGGN CAYGCNTCNACNGARAARGTNGCNATGYTNGGNCARAARACNMGNYTNCCNTGYCCNGTN AARTCNGAYCCNGARYTNACNAARTGGATGAARAAYGGNCARACNATHACNATHGCNTGG GAYMGNTAYAARGTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CCNYTNTTYGARGGNACNCCNTTYAARATGTCNAGYYTNCAY--- ------------------------------------------------------------ ---------------------------ACN------------------------------ ------------MGN------------TAYCAYYTNTCNMGNTCNYTNGGNATGCCNGTN TGGCCNMGNAARYTNGTNAARGAYGGNYTNYTNATGCAYTAYACNGAYYTNGCNATGCAR MGNGARGGNATHGCNMGNYTNMGNGGNGAYGAYYTNGAYMGNGCNTGYTCNTGGMGNGGN YTNAAYCCNCARGGNGTNTCNGGNGARGARAARMGNAGYTAYYTNGARGCNTGGGCNGGN ATHAGYGGNCAYATHAAYGARTCNMGNATHTCNYTNYTNYTNCAYYTNCCNATHYTNYTN GGNCARGCNCAYCARGCNAAYMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARGTNGARAARCARGAYATHAAR GTNGAYATHAAYAAYCAYATGAARGARTAYATGGARGTNAAYTCNCARTGGMGNGGNYTN AARAARTGYYTNAAYAAYAAYTAYGGNGARAARGARAAYYTNACNTAYGTNGAYAARATH TGYGGNYTNGTNGCNAARAARCCNMGNYTNTGYAAYAARGCNACNATHCAYAARCARGTN GARGAYTTYTTYAAYCAYAAYATHGGNCAYYTNAARTGYACNTGYGARAGYYTN------ ATHCARCCNCARACNTCNTCNTCNYTNCCNGTNGCNGCNATHGTNGGNATHAGYATGGGN AGYYTNYTNYTNATHACNATHGTNYTNTGYTGYTTYYTNTGGCARMGN------------ ---YTNAARAARAGYAARGARGARCCNAARGTNATHTAYYTNCCNGCNCCNGGNTCNGAR AAYCAYCCNGTNTAYCAYGAYGCNTTYGAYGARAGYTAYCCNAARYTNCCNGGNAGYGCN CCNCCNTCNYTNCCNAGYMGNTAYACNMGNCAYCCN---GGNTCNGCNYTNCCNAARYTN CCNGGNGARGARACNGARTAYATGGARCCNGTNATHYTN---------CCNGARGGNGCN AARMGNMGNCAYYTNCCNCCNCCNCCNCARGARAAYCCNGGNTAY------GARGCN--- ---CCNCCNMGNTAYTCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GGNTAYAARMGN------AGYAGY CARAGYAARYTNTAYAAYAARGARCAYTTYYTNCARGCNAGYTGYCARTTYGTNGTNMGN GAYACNGGNACNTAYAARGARCARATGTTYAGYCCNGAYGCNYTNGTNGCNTGGGARATG ATHGARYTNGTNCARAGYTTYGCNACNGARGARATGAAYTGYGCNATHTGYMGNCAYAGY YTNTAYGCNGGNAARATHACNAARTGYGGNCAYATHTAYTGYTGGCCNTGYATGYTNMGN TAYYTNTCNYTNGGNGARAGYAAYTAYMGNAARTGYCCNATHTGYTAYGAYGCNGTNAAR GCNGARGAYYTNMGNAGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNYTNGAYYTN CCNTGGGARCARGTNYTNTGYAGYCARGTNYTNGTNCAYYTNAGYATHCCNCARYTNTTY TCNYTNMGNAGYGTNAGYAARTGYTGYYTNGARYTNGTNCARACNCAYTTYAGYYTNCAR TTYCAYYTNAAYACNAGYYTNYTNGGNGAYAARYTNACNACNGGNGCNTTYAARATHATH ACNCARGGNAGYGARTGYYTNAARAGYYTNACNGTNMGNTCNGCNAARTCNTGGYTNACN AAYGAYGTNTTYATHCCNGTNGTNTCNTCNAAYCCNAARYTNACNATHATHGAYYTNACN GGNTGYACNTCNYTNAGYGGNTAYAGYYTNTAYTGYATHGGNGTNAAYTGYCCNAAYGTN AARCARYTNATHYTNMGNAAYTGYGTNTGGATHGGNCCNGAYAAYTTYYTNTCNTTYYTN TGYAGYGAYMGNCCNYTNGCNYTNGARTAYYTNGAYATHACNGGNTGYTGGAAYYTNGAY GAYGARACNGTNAGYCARYTNGTNMGNTTYTCNCCNACNYTNAARCAYYTNYTNYTNGCN AAYYTNTAYGGNGTNACNGAYGCNGCNGTNGTNACNATHGCNCAYTAYTGYCCNGAYYTN ATHACNYTNAGYGTNCARGGNTGYTGGMGNATHACNGAYAAYTCNATHAARYTNYTNGAR CARTAYTGYACNAARYTNAARTGYYTNCARGTNAARGARTGYMGNAAYATHTCNGARAGY AGYYTNATGTCNYTNMGNCARAARAARGTNTGGATHGAYAARMGNGCNCCNCCNGCNGGN GAYYTNMGNMGNYTNGAR------------------------------------------ ---GTNYTNTAYGGNTAYTTYMGNAGYAGYGCNTCNTGGMGNGTNMGNATHGGNYTNGCN YTNAARGGNGTNGARTAYGARTAYAARGCNGTNCAYYTNYTNAARGGNCARCARCAYACN GAYGARTAYAARAARYTNAAYCCNATGGCNATGGTNCCNACNYTNTAYATHGAYGGNGTN AAYYTNACNCARTCNYTNCCNATHYTNGARTAYYTNGARGARMGNTTYCCNACNCCNMGN YTNYTNCCNGARGAYYTNAARGGNAARGCNGTNGTNMGNGCNYTNTCNGARGTNATHAAY AGYGGNATHCARCCNYTNCARAAYYTNTCNGTNYTNAARAARGTNGGNGAYGARAARAAR GARTGGGCNCARTTYTAYATHAAYAARGGNTTYACNGCNYTNGARTAYATGYTNAARAGY TCNTCNGGNMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGGCNNNNGCNNNNNNNNNNNNNYTNNNN YTNTGYGANAARGTNTGGCARTGGMGNYTNNNNGARAGYCCNGARYTNGCNTCNTTYTGY GGNYTNCAYCARNNNGAYCAYYTNTGGGAYGAYATHAGYGARNNNGCNNNNNNNMGNMGN CARNNNNNNNNNGARGARTTYYTNNNNGARGCNAARNNNATHGAYGTNTCNNNNTGYAGY NNNGARGTNNNNYTNNNNNNNACNYTNYTNNNNGAYGGNYTNNNNNNNTAYYTNGCNGGN NNNCCNTTYNNNAGYTAYYTNATGCCNATHNNNNNNYTNGARGGNATHCAYNNNGANATG NNNNNNNNNATHNNNNNNATGAARTTYGAYACNGARCARGAYTTYGARAARTAYATHNNN MGNYTNNNNNNNYTNCCNNNNMGNNNNMGNCARGTNNNNNNNNNNNNNCARAARGGNATH GARGARNNNATHGTNNNNCAYNNNAGYTCNGTNAANNNNNNNCCNNNNCARNNNGARNNN NNNNNNNNNNNNAAYYTNGARGANNNNNNNNNNNNNNNNCCNTTYAARGARGARCAYNNN GGNGTNACNCCNGCNGCNYTNGARNNNNNNNNNNNNGANGCNNNNNNNNNNNNNNNNNNN GARNNNACNNNNNNNYTNNNNGANYTNAARACNNNNYTNGARGANGTNTAYNNNAARAAN NNNMGNGANAANGARGGNATHAAYACNYTNAARAAYGGNGTNAARNNNTAYGARCARTGY YTNGAYTTYCAYYTNNNNTGYNNNATGNNNCCNCARGARGTNNNNNNNYTNGGNYTNNNN GARGTNNNNMGNATHAARAARCARATHGTNGAYYTNGCNACNAARGARGGNYTNCCNACN AAYYTNCARGARYTNYTNNNNGCNATGNNNAAYAARNNN---GGNTTYTTYAARACNNNN GANGAYGTNYTNGANNNNGTNAARAAYYTNTGYNNNAAYMGNATHMGNCCNNNNNNNNNN NNNNNNTTYNNNGAYYTNCCNGAYATHCCNATGGTNATHAARCCNTCNCCNTCNTAYATG ACNTCNGGNCCNATGGGNTAYTAYYTNAAYGGNACNCCNGAYGGNTCNMGNGARGGNGTN TAYTAYATHAAYGCNAGYGAYYTNAAYGAYTGYTTYCCNTTYACNYTNCCNGCNYTNTCN YTNCAYGARGGNGARCCNGGNCAYCAYYTNCARGGNATHTAYTCNYTNGCNGCNACNCAY YTNCCNGCNATHMGNMGNTAYTGYGARGAYAGYAARTAYTAYYTNTCNCCNGCNAARTTY TCNTTYTAYACNGCNTAYGTNGARGGNTGGGGNYTNTAYTGYGARGGNYTNGGNGARGAR ATGGGNATHTAYYTNGAYTCNYTNGARATGYTNGGNMGNTAYAAYATGGARATHTTYMGN GCNGCNMGNYTNGCNGTNGAYACNGGNYTNCAYGCNTTYGGNTGGAGYMGNGARAARGCN ATHGARTAYATGYTNGARAAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGTCNGAYAARYTNGAYACNMGNGTNATHCARGTNACNAAY ATHGCNCCNAGYTGYACNAARGAYCARYTNMGNACNYTNTTYGGNTAYYTNGGNMGNATH AARGARYTNCARATGTAYCCNCCNGAYAAYGCNGARGGNGCN---GTNACNGCNMGNGTN GCNTAYYTNGARTTYGARGAYTCNGTNACNACNGGNGTNGCNYTNCAYYTNAGYAGYACN GTNTTYATHGAYMGNGCNATHATGATHGTNCCNGTNATGGAYGGNAARATHCCNGAYGAR AGYACNGCNYTNCARYTNACNCCNTCNGCNGTNGCNGGNATGYTNCCNGGNCARCCNACN TGGCCNGCNAAYGTNGTNAGYCARGTNACNGGNYTNGGNACNAAYCARGTNATHATGACN AAYGAYCCNMGNYTNACNTCNYTNGGNYTNCCNCARTAYCCNCCNYTNCCNGCNACNACN GAYCCNAGYAARATHGARGARATHMGNMGNACNGTNTAYGTNTCNGAYYTNGAYACNAAR GTNACNTCNGARATGYTNYTNAAYTTYTTYTCNCARACNGGNGARATHAARTAYATHMGN ATGGCNGGNGAYGAYTGYATHAGYACNMGNAGYGCNTAYATHGARTTYACNGAYCARMGN TGYATHGCNCARGCNYTNAGYTAYAAYAAYGTNGTNTTYCARGGNMGNCCNGTNAGYGTN AARCAYTCNACNACNAGYATHACNAARCCNTCNGCNAARTCNGARGCNTCNCARMGNGAR ATHGAYGARGCNATGAARAARGTNAAYGARGCNTCNAARYTNATHTCNGCNGCNAAYACN GARMGNGARAARCAYTCNMGNTCNCCNAGYMGNAARAARTCNMGNTCNMGNTCNAARGGN MGNAGYAGYTCNMGNTCNMGNTCNMGNMGN---MGNTCNMGNTCNMGNTCNGGNMGNMGN AARMGNAGYMGNTCNMGNTCNMGNMGNMGNTCNMGNTCNMGNMGNMGNTCNCCNMGNMGN TCNMGNACNCCNGTNAARMGNMGNMGNTCNMGNTCNMGNGGNAARGCNATHCCNTCNGCN CCNACNATHMGNMGNTCNMGNTCNMGNGAYMGNAARMGNTCNMGNACNMGNTCNCCNGTN MGNMGNAARMGNTCNMGNTCNMGNTCNAAR---------MGNAARTCNMGNACNCCNCCN MGNTCNTAYAGY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AGYMGNMGNTCNCCNACNMGNMGNTCNMGNTCNMGNAGY AAR--------------------------------------------------------- ------------------------------------------------MGNMGNAGYMGN TCNMGNAARGARAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GCN AGYTCNACNAAYATHYTNGAYACNCCNGGNGAYGAYATHGARTTYATHGAYGTNGTNGCN CAYGGNATHAARTTYCAYGGNAGYGAYGGNYTNAARAAYYTNCARTGGYTNGCNGARMGN TCNGCNGARGCNMGNTCNTCNATGATGGARGTNGAYGARAAYACNGTNATHACNCARACN GARGAYGGNGAYGTNAARGTNTCNACNACNATHGAYGCNGTNAARAAYATGGTNTTYGAY CCNAARGCNGARGGNGAYAGYYTNGAYGGN---YTNGGNAAYTCNCCNGGNACNYTNGGN GAYGARGARAARGAYGARYTNTAYGGNAARATHGCNCARAARYTNATHGARATGGCNGAY ACNTAYAGYGCNTCNGCNCCN---CARGARGCNCARGCNGCNTCNCAY---------YTN CCNYTNAAYGAYYTNGARMGNGARATHATHGARTGYYTNMGNTCNGGNGGNGAYAARTAY ACNCAYACNYTNCARGARGCNCARACNGTN------------TCNGCNCARGARACNTAY CARMGNTTYMGNTCNACNGTNCARAAYGCNATGGGNACNGARYTNAGYTGGAAYCAYYTN GCNTTYYTNTTYTTYACNACNCARAGYGTNGTNTCNGCNGTNGGNAARGGNTCNAARGCN GCNAAYCARGCNAARAAYTTYACNYTNACNTAYATHAGYGAYACNTTYATHTCNTGGATH ATGGAYCARGGNGGNTTYGAYAGYATGYTNAGYAAYAGYGAYACNGAYCCNGARYTNGAY ------------YTNGARTGYCARGGNAARYTNAARGGNTCNATHAAYYTNAAYACNATH AARGTNATHAARGARGTNCAYAAYGGNTCNYTNGCNGGNAARAAYAAYGTNTTYCARATH GTNTTYAAYGGNAARAAYAAYTAYTTYACNYTNTAYGTNACNGCNMGNACNGAYGCNGAR MGNCARGCNTGGATHAGYGCNATHACNACNGARGCNACNAARTGYMGNGCNGCNTTYTTY AAYAARCAYCAYAGYGGNGTNTGGACNAARAARYTNGGNCAYTAYAAYTGYTGYTTYCAR AAYGAYMGNAAYGCNCCNGGNTGYATHATHGAYCAYYTNYTNTCNTCNYTNTCNTCNCCN CCNTCNCCNCCNGTNCARCCNCCNGTNAAYCCNAARAARGTNTAYATHGCNGTNTTYGAY TAYGARCCNYTNGARGARGARGAYYTNGARYTNATHCARGGNGARMGNTAYACNATHYTN GARGARACNTCNGARAAYTGGTGGYTNGCNGTNAAYAARGAYGGNGARAARGGNCAYATH CCNGTNACNTAYATHMGNCCNAAYTGYGGNYTNGAYATHTAYGARTGGTAYTAYAARAAY YTNACNMGNGARMGNAGYCARACNATHYTNATGAAYACNMGNAARGARGGNTGYTTYYTN GTNMGNGAYTCNATHAGYCARCCNGGNGARTAYACNYTNGAYGTNTAYACNYTNGARGAY GARGGNACNGTNMGNMGNTAYMGNATHAGYCARAGYAAR---GGNATGTTYTAYGTNGAY GTNAGYCAYACNCARCCNACNATHCCNGARYTNATHAARTAYCAYATGCAYAAYAARCCN GAYYTNGARAARAAYCCNATGMGNYTNYTNGGNTAYTGYYTNCARGTNTGYTGYGGNATG TGYTAYYTNGARGARMGNMGNATHYTNCAYMGNGAYYTNGCNGCNMGNAAYTGYYTNGTN GGNMGNGGNGAYGTNATHAARGTNGGNGAYTTYGGNYTNGCNMGNATGGTNYTNGCNGAY GAYGARTAYACNYTNTCNGARGGNTCNCARTTYTCNTTYAARTGGGTNCCNCCNGARGTN YTNACNCAYMGNAARTTYAGYAGYAARTCNGAYATHTGGGCNNNNGGNATHYTNATGTGG GARACNTAYTCNYTNGGNAGYACNCCNTAYCCNAAYATGAAYCAYTCNGAYATHGTNAAR AAYGTNGCNGARCARMGNAARMGNYTNGCNAARCCNMGNYTNGCNACNGARTTYGTNTAY GGNATHATGAARACNTGYTGGGARCAYGARGCNTCNGAYMGNCCNGAYTTYAARACNYTN AARTCNAARYTNTCNAGYYTNATHACNAARGAYACNTAYATH------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AGYACNCCNTCNYTNTCNYTNATHTCNACNGARATHACNATHCCNAARATGMGNGGNCCN GCNGTNYTNCARGCNGCNTAYTTYACNAAYAAYCCNCARGCNCCNCCNGTNTTYTTYCAR TGYAGYAAYATHTAYGTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATGAGYCARCAYGAYYTNAAYGCNTTYTAYCAYAARTAYGTNMGNGAYCCNCAR ATHYTNTGYGAYTCNYTNGARMGNATGGGNAGYYTNYTNGAYGGNGGNTGGGAYATGTGY YTNATGAGYCCNTAYGCNCCNCCNTCNGGNAGYTGYYTNACNTAYTCNTTYGGNATHAAY MGNGAYTTYTCNTTYGAYGAYGAYGTNGGN---GAYTAYGGNTGYGARGTNCAYTCNTTY GAYCCNATGACNTCNTTYACNGAYCAYCARMGNAAYCARCAYGTNACNTTYCAYMGNATH GGNATHTCNGGNCARGAYGARMGNGTNGARGTNGCNAAYCAYYTNAARACNYTNTCNACN ATHMGNAARGTNYTNMGNCAYCCNCCNMGNAAYYTNGAYTTYYTNAARATGGAYGTNGAR GGNGCNGARYTNGCNAGYYTNCAYACNGCNYTNCARGAYGGNAGYYTNMGNGAYGTNMGN CARYTNGCNTTYGARATHCAYCAYGGNTTYCCN------YTNTCNAARTAYATGGARTAY YTNTCNGTNYTNMGNCARYTNTAYGAYCARGGNTTYMGNATHTAYTAYTTYAAYMGNAAY GCNMGNAGYGARTTYYTNMGNGARGGN------AARMGNMGNTCNAARYTNYTNGARYTN CAYATGYTNAAYACNGCNTTY---GCNAGYYTNAAYTAYGGNTCNGGNAGYYTNACNAAR ACNACNGCNGGNCARGTNCCNTGGGTNMGNYTNAARMGNMGNGAYTAYATHGCNYTNGAY GAYYTNGTNAGYGGNMGNACNCCNCARAGYCCNAAYACNGTNAARYTNGCNTCNCCNGAR CCNTCNAARYTNYTNCAYGCNCCNAGYTTYAARAGYAARCCNYTNATHGTNACNACNGAR GCNAGYMGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARATHGCNCAY ATGATHGCNTTYATHGAYCARGARGCNTCNGARAARGTNGARGARATHGAYYTNAARGCN GARGARGARTTYAAYATHGARAARGGNMGNYTNGTNCARCARGCNMGNGTNAARATHATG GAYTTYTAYGAYMGNAARGARAARCARGTNGARYTNCARAARAARATHCARAAYTCNAAY ATGCARAAYAAYTCNMGNYTNCARATHYTNAARAARAARAAYGARYTNGTNAARGARATH ATGGARAARGCNMGNAARGARYTNAGYCARYTNCCNATHAARGARGCNGCNAARTAYMGN GARATGYTNAARAAYYTNATHYTNCARGGNYTNGTNMGNATGATGGARAGYAARGTNGCN ATHMGNGGNMGNAGYGARGAYGCNAARATHATHAARGGNTTYTTYCCNGARATHACNGCN GCNTAYAARGARYTNTTYAARGGNCARTTYGARGTNCARYTNACNTTYGAYGARGARAAY TTYYTNCCNTCNGAYATHTCNGGNGGNGTNTGGYTNYTNGCNATGGGNGGNAARATHACN GTNGTNAAYACNYTNGAYGARMGN---AGYGARTCNGTNACNGGNGCNTAYGTNYTNTGY YTNYTNTTYCARGGNMGNGTNCAYCARTAYMGNATHYTNCCNGAYAARGAYGGNMGNATH TCNGTNCARTCNGARGGNGAYATGCARCCNCCNAGYTAYAAYGAYAGYYTNATHAGYTCN TAYGTNAAYAARGGNGARAARAAYGGNYTNGTNTGYGCNYTNAARAARCCNGTNATGCCN GARGGNACNGARATH--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNATHGTNTAYATHCARMGNACNGARTCNTTYAGY GCNGCNCAYMGNYTNCAYAGYCCNYTNYTNTCNGAYGARGARAAYTCNGCNYTNTAYGGN AARTGYAAYCAYCCNCAYGGNCAYGGNCAYAAYTAYAARGTNGARGTNACNYTNMGNGGN CCNGTNGAYCCNGTNACNGGNATGYTNATHAAYATHGTNGAYYTNAARMGNTAYATHGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYGTNATHCARGTNGCN CCN---ACNGAYGGNACNTTYCARCARTCNGCNTCNGGNTTYCARACNYTNACNGCNNNN GCNCARCCNCARGTNATHAGYAAYGCNCCNACNGTNCARYTNGGNGGNTCNACNGCNCAR GGNTCNACNATHGTNCARTCNAAYGGNGTNYTNCARAAYGTNGTNCARCARGCNGCNCCN GCNCARGTNGCNCARCARCAYTCNCARGCNGTNGCNACNGGNACNGCNGCNTCNGCNGGN GTNCCNGCNGGNATHCCNCARATGYTNTTYYTNAAYCARGTNACNATHAAYGGNCARACN TCNTAYGTNYTNGTNGAYGCNAAYAAYAARCCNGTNCARYTNCCNCARGGNATHCARGTN ATHAAYATHCCNAAYACNCARATHCCNGGNCARCCNATHCARATGCCNGGNGGNGAYACN GARGGNGARCCNYTNTAYGTNAAYGCNAARCARTAYCAYMGNATHYTNAARMGNMGNCAR GCNMGNGCNAARYTNGARTCNGARGGNAARATHCCNAARGARMGNCARAARTAYYTNTAY GARTCNMGNCAYMGNCAYGCNYTNAAYMGNGCNMGNGGNTCNGGNGGNATHTTYGTNGGN ---TCNGCNTCNYTNGAYYTNGTNYTNATHGTNGGNAARGAYMGNCAYAARGTNCAYYTN GARGCNACNAARCCNGARGGNGARAARGAYTGYCCNACNGTNAARAAYYTNACNGARGCN GTNAARGCNGCNACNGGNATHGARCCNGARTGYCARAARYTNATHTAYMGNGGNMGNACN YTNTTYAARGAYTTYAARACNGAYACNGAYAGYYTNCARAARGARYTNTCNTCNYTNTCN ATHCAYAAYGGNGAYMGNATHATGGTNYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGAARGARATHATHCARMGN YTNGTNGAYAAYTTYGAYMGNYTNCARGTNGTNGTNTTYGAYGARGAYACNATHYTNAAY AARCCNGTNGARGARTGGCCNATHGTNAAYGGNYTNGTNTCNTTYTTYTCNCAYGGNTTY CCNYTNGARAARGCNATHGCNTAYMGNGAYYTNMGNAAYCCNTTYATHGTNAAYGAYYTN GAYATGCARTAYATHYTNCARGAYMGNMGNAARGTNTAYGCNATGATGAARGARAAYGAY ATHCCNCAYCCNMGNTTYGCNGTNYTNGAYMGNGARAAYGAYCCNGAYTGYAARGTNGTN GARACNGARGAYTCNATHGARGTNAAYGGNAAYYTNTTYATGAARCCNTTYGTNGARAAR CCNGTNGAYGCNGARGAYCAYAAYATHTAYATHTAYTTYCCNGTNTCNGCNGGNGGNGGN AGYACNMGNYTNTTYMGNAARGTNAARGAYMGNAGYAGYATHTAYTCNMGNTTYTGYMGN GTNMGNTCNAARGGNTCNTAYYTNTAYGARGAYTTYATGCCNACNGAYGGNACNGAYGTN AARGTNTAYACNGTNGGNCCNGAYTAYCARCAYGCNGARGCNMGNAARTCNCCNGCNYTN GAYGGNAARGTNGARMGNGAYGCNGARGGNAARGARATHMGNTAYCCNGTNYTNYTNAAY AAYMGNGARAARYTNATHGCNMGNACNGTNTGYAARGTNTTYAARCARAAYGTNTGYGGN TTYGAYYTNYTNMGNGCNAAYGGNCARCAYTAYGTNTGYGAYGTNAAYGGNTTYAGYTTY GTNAARACNTCNAGYAARTAYTAYGAYGAYTGYGCNAARATHYTNGGNACNYTNGTNATG MGNGCNTGYTGYCCNCARGTNCAYATHCCNTAYCCNATGTGYACNGCNCCNGARGAYATH CCNGTNGTNCARACNACNTCNGGNTCNGARGARGARATHYTNGGNCARAGYGTNYTNGTN ATHYTNGCNGGNTTYGARACNACNTCNACNACNYTNCARATGACNYTNTAYYTNYTNGCN AARCAYCCNGAYATHCARGARAARYTNTAYAARGARATHCARGCNYTNYTNCCNTCNGAY AAYCCNTCNCAYGAYGARGTNAGYAAYGTNCCNTAYYTNGAYCARGTNATHAAYGARGCN YTNMGNATGTTYCCNCCNGTNGCNATGATHGCNMGNGTNGCNAARGAYACNMGNACNTAY GAYGGNGTNACNATHCCNGGNGGNACNAGYGTNTTYGTNCCNTAYTGGCAYATHYTNAAY GAYCCNAARATHTTYCCNGAYCCNGARAARTTYGAYCCNGAYMGNTTYTCNGARGARMGN GARAARMGNGAYATGGCNTTYGTNGTNTTYGGNCAYGGNCCNMGNYTNTGYYTNGGNAAR MGNYTNGCNTAYYTNGARYTNMGNCAYGCNYTNGTNMGNATHGTNAARMGNGTNMGNATH TCNATGAAYGARAARYTNGGNGARCCNYTNAARATGYTNYTNGTNGTNATGGTNTCNTCN GCNGTNGAYYTNYTNAAYCAYTCNCAYYTNCARGCNGARGGNATHAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGGGNAARAARCAYAARCAYGGNAARCAY--- ---TCNTCNTCNTCNAGYTCNTCNTCNAGYGAYTCNTCNGAYGAYGARTGGMGNCAYYTN CCNAARCAYGARAARAARATGMGNAARAARTGGAARAARCARATGMGNAARGGNAARATG CCNCAYGGNTCNYTNCCNCCNTGGCARGGNGGNCCNGCNTGGTCNCCNCCNTCNMGN--- ---AARCCNGGNAARTAYGGNAAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GARACNYTNGAYCAR GAYAARYTNYTNAARACNCARGARYTNCARGCNGCNYTNGCNGARCARGCNATHYTNAGY GARGARAAYAARTCNYTNAGYCARMGNTCNGCNGARYTNCARCAYGAYYTNCARAAYATH GARGCNCARAARGARGARATHGARTCNGARAARGAYCARGCNGARYTNAGYYTNCARGAY CAYGTNGARMGNYTNACNCAYYTNGARGTNGARAARCARGCNATHTCNGARCAYGCNTAY GARYTNGARAGYACNATHAAYGAYYTNGARTCNCARAARGARATGACNGARAARGARYTN AARGARGARATHAARGCNMGNYTNYTNGCNGARCARMGNYTNAARGAYGCNGARCARTCN GTNGTNAAYATHGAYACNGTNGTNCARTCNCARTCNCAYAAYATHGARGTNGARGCNCAR AARACNATGACNGTNAAYGTNAARAARYTNAARGTNTTYTTYGARGAYYTNGCNGARGAR GCNAARGTNACNTCNGCNAAYCCNATHATHATGMGNAAYGGNATGGTNGCNMGNAARACN YTNGCNMGNMGNGCNAARACNATHMGNTAYGARAAYMGNAARMGNTCNAGY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ACNYTNTGY AARYTNYTNMGNYTNMGNGAYGTNTGGGCNACNATHATGYTNTAYTCNGTNATGTCNTTY GTNACNATHGCNATHGAYGAYGTNTTYCCNGTNTTYGCNTCNATGAGYAARGAYYTNGGN GGNYTNGGNTTYGAYACNAARGARATHGGNATHGCNATHGGNGCNGCNACNATHCCNYTN YTNGTNATHCARGTNAARYTNTAYCCNTTYYTNGTNTCNMGNTAYGGNATHMGNAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARCCNCCNGARTTYYTNAARAAR MGNGGNACNGGNATGTCNGCNYTNACNTCNGTNAARMGNGTNGTNAARGTNMGNCAYAGY TCNTCNCCNACNAAYYTNMGNAAYCARGARGCNGTNMGNATGAGYATGTTYCCNAGYGCN AARCCNAARYTNCCNGAYGARCCNGAYAARATHGARMGNGAYGAYTGGCCNGGNCCNGCN TCNCCNGCNGCNYTNYTNCCNGARATHYTNMGNCARMGNMGNMGNAGYAARGGNGARAAR GAYGAYGARGAYGARGARGAYGARGTNAARGARGAYCCNMGNATHAARMGNGARATGGAY GARATHTCNAARATHAARGAYGARAGYGGNATHGGNAARGTNATHTAYAARGARYTNGAR GGNYTNAARGCNAARCCNAGYCARCCNYTNGAYCCNTGGAARGCNTCNMGNGCNCCNAGY GCNAARTTYGARCCNMGNTAYMGNACNMGNTTYCARTCNCCNATGTTYGCNTCNCCNTCN MGNTTYYTNGAYMGNCCNMGNTAYGCNTGGGAYGAYAGYGAYATHMGNACNTAYMGNTCN GTNTCNACNYTNGCNAAYYTNCCNACNCCNMGNCCNGGNTAYGGNCCNCARTAYGTN--- ---MGNGTNTCNACNYTNCCNYTNGCNGGNGCNTAYGGNGCNMGN---GAYTAYMGNTTY TTYGAYTTYGAYGARTCNGAYGAYMGNMGNTCNACNCAYACNTCNTCNTCNACNYTNACN GGNGAYACNAGYTCNMGNMGNCAYGAYTCNTCNTAYAGYGGNTAYGAYGTNCCNTCNATH CCNYTNYTNCARYTNCARAARAGYACNTGGCAYACNGARTAYGARCCNACNATHTAYTCN TAYGAYAARYTNAARATHACNAAYTTYGAYYTNCCNAARGAYGTNGAYCCNAAYCAYYTN GARATHCAYYTNACNAAYGARGAYTTYGARGAYYTNTTYAARATGCCNMGNGAYMGNTTY TAYMGNATGGCNGARTGGAARMGNAAYCAYGTNAARMGNACNATHGAYYTNTAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNGAYAAYAARGCNGARTCNAGYTTYATGCARTGG AARCCNGTNTGYTAYTTYGAYAARGGNMGNAGYMGNTCNACNGCNACNAARGTNAARCAY TAYGAYYTNACNAAYATGTCNGARMGNAGYYTNGTNAAYAARACNYTNATHYTNGCNYTN TTYGGNGARAARYTNTGGGAYGAYACNAAYACNATHGTNMGNGCNATGAAYATHTCNTTY GGNYTNCCNAARGAYGGNTAYTAYGTNAARAAYAAYTTYACNGCNTGGACNGCNGCNYTN GGNTAYGGNACNCCNCCNAGYGAYTCNATHTCNATHACNGTNATHGCNATHATHTCNGCN GGNYTNGGNATHCCNGTNGTNATHATHATHGTNGGNGGNGTNTAYACNATHTTYMGNAAR ACNATHAARAARGGNGGN------TAYGCNCCNATHAGYGGNTCNGTNAGYGTNAAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GAYGTNTGYATHACNGTNCCNATHTGYAAYAGYGGN---GTNGCN---------AAR AARTTYTGYYTNYTNGARGGNTCNCARTCNTCNGCNCARTTYTAYGTNTTYGTNGGNGTN ATHGTNTTYYTNTAYTGYYTNGCNGCNYTNGTNYTNTAYGTNTTYTTYGAYGAYYTNTAY MGNMGNAAYACNMGNATHATHATHATHGAYTTYGTNGCNTCNATHGTNYTNACNATGYTN TGGYTNATHGCNTCNTCNGCNTGGGCNTCNGGNGTNAAYGAYGTNAARATGTAYACNGAY CCNAAYGARGGNCAYATHTTY---AARAAYYTNGARGARTGYGTNAARGARCCNAARGCN TGYACNACNGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CAYCAR TTYTGGACNGTNATGGARGARATHGAYACNAAYACNTGGGTNYTNGARCCNGARAARCCN TCNTAYTCNAGYATHCARMGNMGNATGTCNATHGGNCCNAAYATGTCNATHCAYATHACN GTNAAYCCNYTNCARCCNTCNTGYGTNCCNATHTGYAARYTNATGGGNGCNCARGCNGCN ATHGCNCCNATGAARGARAARYTNAAYAGYAAYYTNCAYMGNTGGGAYGTNGARMGNTCN YTNYTNAAYAAYYTNCARGARATHATGGARYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AGYGTNGCNCCNCCNCCNCCNCCNCCNCCN CCNCCNCCNCCNCCNCCNACNATHGTNAARAARGAYGAYGARAAYAGYATGGAYATHGCN TCNGAYGARGARGARCCNAAYGCNGGNCCNAGYATHGARGGNCARCARTTYTCNAAYTGG ATGCARCARCARCAR------------TGGTGGCCNACNGTNGAR---CARGCNTGGATG GGNCARCCNGCNATHCCNAAYAARGAYGAYTAYAAYGGNGAYGAYCAYCARMGNATGCCN AGYTAYGGNGTNAAYCARAAYTCNTCNGAYAARGAYAGYGGNTTYCARAAYTAYTGGGAY GGNCARGARGGNAGYAGYGGNGAYATGMGNCCNACNTCNYTNYTNGGNGAY--------- MGNCCNGAYTTYCAYMGNCAYCAYCCNCCNTCNCAYCAYCAYCAYCAYAARCCNGGNAAY CAYGGNTCNMGNATHGGNAGYMGNYTNGAYCAYGGNATHCCNCCNGTNCCNGARGARTCN GGNYTNGAYGCNGCNAARMGNMGNACNYTNCCNGTNTGGATHMGNGARGGNYTNGARAAR ATGGARMGNGARAARCARAARCARCARGARAARGARYTNATGAARAAYGARACNAAYACN YTNGAYAARGARACNCARGARAARMGNGARGARGTNGAYGAYGAYGGNYTNCCN------ ------------AARGTNCCNMGNAARAGYMGNTTYGAYTCNGAYGAYGARGAR------ ---GARGARAARAARGARMGNAARGAYGARAGYGCNGAYTCNAARTCNMGNTCNMGNAGY AARTCNCCNTCNGGNTCNCCNTCNCCNAGYAARGARACNATHCCNTCNGTN---GTNAAR MGNAGYCCNTCNCCNGARGCNTTYATGACNGARGARGARAARGARATGGCNYTNATGATG AARGTNAARMGNYTNYTNACNGARACNYTNYTNGARGTNACNGAYAARGARATHAARTCN GTNGCNACNGARGTNTAYCARMGNGARMGNAARAARGCNYTNAARGCNCCNGCNAARCAR YTNGCNAARTCNTCNGCNYTNGCNTCNYTNTCNGCNYTNGGNYTNGGNTAYGGNTCNGGN AGYGARATGAGYGAYGCNGARCAYGGNGGNAARAGYGARGARGARTCNGAYTCNGAYYTN GAYGARAARATHAARCARAARAARGCNGARTTYGCNAARMGNCARMGNATHTTYAGYGAY GCNGARAGYGAYGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTAYAAYGGNATHGGNYTNCARACN CCNMGNGGNAGYGGNACNAAYGGNTAYGTNCARMGNAAYYTNGCNTTYGTNAARAAYAAR AARGAYMGNATGGAYTAYAARACNGAYGAYGAYYTNCARAARYTNGARCARTCNATGAAY MGNCARCCNAAYMGNGARATHYTNGAYCAYGARMGNAARMGNAARGTNGARGTNAARTGY ATGGARATGCARGARYTNATGGARGARCARGGNTAYACNAARGCNGARGTNAGYTCNAAR GTNAGYATGTTYMGNMGNATGYTNATGGCNAARGARGGNGTNTCNGAYGCNTGYACNGTN GARAARGAYGARCAYGGNMGNCCNATHGCNAARGARACNCAYCARYTNGCNGARGCNAAY CARCARAARAAYGARAARYTNAARGARGCNTTYGGNYTNTCNGGNTAYGTNGARGGNAGY TCNTTYGAYCCNGARMGNMGNGCNAARGARGARGCNGCNAARGCNACNGCNATGGCNACN AARAARTAYAGYATHGTNCARAGYTCNGARGARGAYGGNGARAARACNGARAGYTCNCAR CCNCCNAARAARAARAARAARAARTCNMGNCAY---GAYAGYTCNTCNTCNGARMGNAGY AARGARAARCAYAARAARAGYMGNAARCAYAGYMGNMGNGAYMGNGARATGAAYATHYTN CARYTNACNAAYAARCARYTNAARYTNGAYYTNCARGCNGARCARGAYYTNGTNYTNCAR YTNMGNAARMGNYTNAAYGGNGCNGARAARCARAARYTNGARGCNACNACNTCNGCNAAY GCNCARATHGCNAGYYTNGARACNCARYTNGCNAARGTNMGNTCNNNNYTNNNNAARGCN GARGCNAAYMGNCAYAAYYTNGARTTYGARYTNACNAARAGYCARMGNGAYGTNAAYCAY GTNAARAARAAYGCNAARGARMGNGARGCNYTNYTNGTNGAYGGNTCNGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNACNAGYTCNACNACN ACNGTNGAYCCNTTYCARGAYGCNGAYGTNAARCAYGAYGAYCAYGAYTAYTAYACNACN GAYATHATHMGN---AAYCARTTYTCNAARTAYTGGACNGARYTNGARAAYGCNAARATH CAYTCNACNYTNTCNAGYGGNCAYMGNGTNGCNGCNGTNYTNCCNYTNAARTTYAGYTTY CCNTTYTAYGGNCAYCCNGTNAARAAYGTNACNGTNGCNACNGGNGGNTTYATHTAYATG AGYCCNTTYYTNCAYAARTGGYTNACNGCNACNCARTAYATHGCNCCNYTNATGGCNAAY TTYGAYCCNTCNTTYAGYAARGAYTCNAAYATHTAYTAYCARAGYYTNGAYGAYAARTTY ACNATHGARTGGAARAAYYTNGTNYTNCARGAYCARAAYGARACNGGNMGNTTYCAYTTY CARGCNAGYYTNCAYGCNAAYGGNAGYATHTAYTTYYTNTAYAARCARGTNCCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYTGYTTYGAYYTNGCNGARTGYTGGACNAAYTCNGTNGAYGGNGAY CCNGARTGYYTNMGNAARYTNTAYTCNAARGARGTNAARATGYTNAAYYTNTTYTGYCCN ATGAGYGGNATHGAYCARGARATHAGYTAYTTYATGTTYAARAARTTYAAYTGGCCNYTN ATHGCNGGNGGNTGYGTNAAYGARAARTTYATHMGNCAYCCNGARGGNACNATHGAYMGN TCNMGNAARTCNAGYATHATHTCNGGNYTNGCNGTNTGYGGNGARGAYATHCARGTNGCN TCNGTNYTNATHMGNTCNGAYGTNGARACNGARGARGARGTNGAYGARGTNGTNAARCAR YTNGCNAARTTYGAYTTYCCNYTNGARAARAGYATHGGNYTNATGTAYGCNTGYGTNGGN MGNGGNATHCAYGTNTAYGAYACNCAYAAYGTNGARTCNAARGTNTTYMGNAARTAYTTY CCNMGNACNCCNYTNATHGGNTTYTTYGGNAAYGGNGARATHGGNTGYGARCAYCCNGAY TCNTTYTTY------MGNAAYGAYACNAARTCNAGYTCNAAYGGNGAYTGYGTNTGYGCN AAYTGYAAYGARAAYYTNTCNAARGCNCARCARMGNAARMGNYTNGARGGN---MGNAAR GARYTNAAYCARTAYAARYTNAARCAYCCNCCNAARYTNTTYCAYGCNTAYTCNACNGTN ATGTGYYTNATHTCNYTNCCNGAYAARCARGCNAARTTYCARGARGTNACNTCNTGGYTN AARGAYYTNTTYGGNGAYGARCCNGTNCCNGAYTTYGARATHAAYGCNAARACNATHGAR GTNYTNCAYGGNYTNTGYGARACNGTNAARMGNAAYGAYGARAARGTNCAYYTNGTNGTN GARGAYYTNAARCARAARAAYGCNGARTAYAAYGCNGAYGCNCAYMGNYTNACNTCNYTN YTNTCNMGNATGAAYYTNGAYTCNAGYTGYTTYACNGARTCNGGNMGNAARAGYGTNMGN ACNYTNGCNCAYYTNGGNACNTCNYTNAAYATHAARAAYTCNTCNGAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARNNNNNNNNNNNNNNNAGYTCNNNNNNNNNNNNNYTNNNNNNNNNNNNNTGY NNNNNNACNNNNNNNNNNNNNNNNYTNGGNCARGGNAARTGYCCNACNACNCCNACNCAR AGYGGNTTYCARYTNTCNTCNTAYYTNGGNMGNTGGTAYGARTAYCARMGNTTYCCNAAY TGGTTYGARGTNGCNATGAARTGYGTNACNGCNGAYTAYTCNGTNAARCCNAAYAARGAR ATHAAYGTNATHAAYGCNGGNGTNMGNGAYYTNGGNTTYTTYGGN------------ACN AARAAYACNTCNATHGAYGGNACNGCNACNGTNCCNGAYCCNTCNAARCCNGCNGARYTN ATGGTNTCNTTYTCNAARTAYCARCCNGCNGGN------AARGCNAAYTAYTTYGTNGTN GARACNGAYTAYACNAGYTAYTCNGTNGTNTTYTCNTGYGCNGARGTNCCNATHYTNCCN ATHAAYGTNCARTTYYTNTGGATHYTNACNAARGARCCNGGNAARGCNCCNACNAAYYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNTCNYTNAAYCCNAAYYTN MGNGARGTNGGNGARGAYGARGAYTGGACNYTNTAYTGGACNGAYTTYTCNGTNGCNYTN GAYMGNGTNATGGARATGAARAARTAYCARAARATHAAYCAYTTYCCNGGNATGAAYGAR ATHTGYMGNAARGAYYTNYTNGCNMGNAAYYTNAAYMGNATGCARAARATGTTYCCNAAR GAYTAYAAYGTNTTYCCNAARACNTGGTGYYTNCCNGCNGAYTAYGGNGAYTTYCARGCN TAYATHMGNCARAARAARAAYAARACNTAYATHYTNAARCCNGARTCNGGNTGYCARGGN MGNGGNATHTGGGTNACNAARAAYCCNAARGAYATHAARCCNCAYGARCAYATGATHTGY CARGTNTAYATGAAYAARCCNTTYYTNATHGAYGGNTTY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNMGNAARMGNATHGTNGGNGGNTAYCAR AGYACNCAYGGNGARTGGCCNTGGATHGTNTCNATGCAYTAYYTNCCNGARYTNGAYTTY ACNAAYMGNTCNGGNTTYAARCAYYTNTGYGCNGGNTCNATHATHACNCCNGARTGGATH GTNACNGCNGCNCAYTGYGTNGAYGAYGTNGTNATGGAY---GGNYTNGGNAAYGTNTCN AAYTGGMGNGTNAARGCNGGNGTNTAYGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGMGNMGNMGN YTNGAYGAYCCNCARYTNYTNACNYTNGAYGCNGTNTTYAAYATGYTNATHTCNTTYMGN GARATHCARGAYTAYAARGCNATGGTNAARYTNGTNGARGAYGTNTCNAGYAAYACNAAY ATHAARATHGAYAGYAAYCARGGNATHYTNAAYYTNTAYGCNTTYGCNYTNAAYMGNAAY GGNAAYMGNGAYAARGCNYTNAGYGTNATHYTNAARGCNATHGARAARTCNGAYACNCAR GTNCCNGAYATGATHTGYYTNTGYGGNMGNATHTAYAARGAYAARTTYGTNGAYTCNGAY TAYTCNGAYATGGAYGGNYTNCAYAAYGCNATHAGYTGGTAYMGNAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATHYTNTTYYTNGGNYTNTAY GAYGCNGGNAARACNTCNYTNYTNCAYTCNYTNAARYTNGGNGARGTNGCNACNYTNATH CCNACNATHGGNATGACNYTNGAYACNYTN---AARACNAARGCNATGGARATHATHACN TTYGAYATHGGNGGNMGNAGYACNYTNMGNCCNYTNATGMGNTTYTAYCAYGCNGGNGCN TCNGGNGTNGTNTTYGTNYTNGAYAGYAGYGAYAARGAYCARYTNGGNTAYGCNATGGAY ATGATHGAYMGNTTYATHATHCARGARGARGAYYTNGAYAAYACNGTNGTNATGGTNYTN GCNAAYAARCARGAYYTNTCNGAYGCNATGAARCCNMGNGARATHAGYGAYAARYTNGAR CAYMGNTTYCARGGNAARYTNGGNAAYMGNACNYTNTTYYTNCCNTGYAGYGTNACNCAR GGNCAR------GGNGTNTTYGARGCNYTNTCNGCNTTYGARGARCARATH--------- ------------------------------------------------------GAYYTN AARAGY------------CARGGN------------------------------------ ------------------------TTYTGYAAYGCNTGYACNGARACNAARAAYGGNTGY TGYTAYGAYACNYTNGTNCARCAYYTNMGNYTNCARGTNTGGAAYATGTGGTAYTTYTGG TTYYTNTTYGTNTTYATGATGGTNTCNTGYTTYGGNGGNTGYGGNTAYTAYMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNGAYCARGAYGGNGTNGTNTCNGCN GARGGNTGYGAYCARATHATGTCNCAYGGNYTNGGNGTNMGNTAYGCNTTYATGGGNCCN TGGGARACNGCNTAYYTNAAYGCNGARGGNATGATGAGYTAYGGNGARMGNTAYTCNGAY ATGATHYTNGGNATHCARGARAGYTTYGGNCCNCCNGCNMGNATGGARGGNCCNACNYTN GAYYTNATHCARTCNGAYATGGARMGNATHGCNGGNTCNACNGARGAYATHGARGGNMGN MGNGTNTGGMGNGAYMGNMGNYTNTCNGCNYTNGCNAAYYTNAARTCNAAYATGGAYAAR GARGAYAARAARGAYGTNGTNTTYTCNTTYGAYACNACNGGNTCNATGTCNCARGTNYTN GAYGARGTNAARGGNMGNATGACNGAYATHGTNCARMGNYTNCARGCNGAYATHCCNGGN TTYCARGTNGGNGTNATHGCNCAYGGNGAYTAYTGYGAYGCNGAYCAYTTYTAYGAYATH MGNACNYTNGAYYTNACNAAYTGYYTNCCNGAYGTNGTNACNTTYGTNACNAAYACNGAY GGNACNGGNGGNGGNGAYATHCCNGARTGYTAYGARYTNGCNYTNMGNCAYGCNAAYCAR ATGTCNTGGACNGCNGGNAGYCARMGNATHYTNGTNGTNATHGGNGAYGCNTAYCCNCAY GGNCCNGAYTAYGCNYTNAAYAARYTNGCNATHGAYTGGCARAARGARATGGAYGCNYTN GTNAAYAARGGNGTNMGNATHTAYGGNGTNCARGTNCARGARGAYCCNGARTCNACNCAR TTYTTYCARGARYTNACNAAYMGNTCNGGNGGNCARCAYYTNAARYTNGCNAAYATGCAY MGNATHTGYGAYGTNATHATGGGNATHTGYTAYMGNGARAARGGNCCNCARYTNTTYCAR AAYTAYGARGCNGARGTNMGNCARMGNGARGCNGARMGNTTYAGYAAYGAYYTNGARTGY GTNTTYGGNACNYTNMGNCCNGARGARAGYYTNGAYGGNCARCARTGYGARGCNACNAAY GARGARTCNYTNCARTGYAAYATHTGYYTNACNGAYTAYGARGAYGGNGAYCARAARMGN CARYTNCCNTGYAARCAYGARTGYCAYCCNGAYTGYGTNGAYAARTGGYTNAARACNAAY GCNACNTGYCCNGTNTGYMGNTCNGARGTNAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARYTNTAYGARTGYTGYTGYTGYTTYGAYGAYGARTGYYTNTTYGARGAYATGGCN AGYTGYCCNGARGGNCAYYTNTTYTGYAARACNTGYGTNATHMGNTCNACNGARGCNGGN TTYGGNGARATGAARATHMGNTTYCCNTGYYTNACNGGNGARTGYGARCARAAYATHTCN YTNACNACNYTNCARACNATHATHCCNGCNACNYTNTTYTCNAARATHGTNAGYMGNYTN CARGARGARGARYTNCARCARGCNAAYATHCCNGAYYTNATHTCNTGYCCNTTYTGYCCN TTYGCNACNATHATGCCNCAYCARGARGAYAARGTNTTYAARTGYYTNAAYCCNGARTGY TTY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MGN AARACNTGYATHMGNAARGGNGARGTNACNACNGCNAGYCCNTGYCCNATHTGYMGNGAY GARAAYYTNGTNYTNGAYGCNAARAAYGTNAARYTNYTNGARCAYTTYGTNTCNCCNAAY TCNGGNGARATHYTNGAYATGCCNCARACNGGNYTNTGYCARACNCARAAYMGNAAYYTN ATHGTNTCNATHATGTCNGCNTGGGAYCARGGNYTNYTNGARATGAARGTNCCNTTYMGN GARTAYGAYTAYGAYGAYTAYAARACN---------------------------MGNGAR YTNTAYYTNTAYAGYGAYGTNAARGARCARACNAAYCCNATGGCNAGYYTNGTNYTNCAR GGNYTNACNAGYCARCCNGTNAAYCAYGARATGAAYGGNCAYMGNAARAAYGCNTCNTCN GAYGTNGAYMGNTCNCCNGAYGTNGAYAAYGAYAGYGAYGAYGAYGAYGTNCCNGARTAY AAYGAYTAYTCNTCNAAYGAYGAYATGAGYGAYAGYGARCCNACNATGACNGARGCNMGN GCNMGNCARMGNAARCAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGAYTCNTCNCCN TTYTCNGARGTNATHGTNTCNGAYCCNTCNTTYYTNGAYAGYGARTCNGCNMGNAGYATG TGYCCNCARTGYAAYAARTCNMGNAARTAYTAYTGYTAYGAYTGYTAYGTNCCNYTNCCN CAYYTNGARAGYAARYTNCCNTGGGTNAARYTNCCNGTNAARGTNGAYATHATHAARCAY CCNAAYGARAGYAGYGGNAARAGYACNTCNCCNCAYGCNGCNATHYTNGCNCCNGAYGAY GTNACNATHCAYACNTAYCCNTGYATHCCNGAYTAYCCNGCNGAYAARGTNGCNYTNYTN TTYCCNTGYGAYGGNGCNATHTCNYTNTCNGARGTNGCNAGY------CARGGNYTNYTN GGNMGNGTNAARCCNGCNACNAARGTNGARCCNAAYACNTCNGAYGCNGCNAARYTNGAY GGNTGYGAYCCNMGNAAYTCNGGNYTNGGNACNTCNTGYGARTCNCCNAARATGAAYMGN CARGAYTCNGGNYTNCCNAARGCNGAR------------------------------GCN GAYGAYTCNCARACNGCNAAR------GAYCCNTCNTGYYTNTGYGAYAGYGARMGNCCN GCNCCNAAR---------MGNTCNYTNGCNGAYGCNGAYAARAAYGGNGAYGAYGGNGGN TAYGGN---------AARMGNMGNAARACN---GGNAAYTGYCCNYTNGARMGNGTNATH YTNATHGAYTCNACNTGGAAYCARACNTGYAAYATHATHAGYGAYGARMGNYTNAARGGN YTNCCNMGNGTNCARYTNACNAGYCAYGARACNCAYTTYTGGMGNAGYCARCCNGGNATH CCNAARACNTTYYTNTCNACNATHGARGCNYTNTAYTAYTTYYTNTGYGARTTYCAYGCN GCNTTYGTNGARGARGCNTAYAGYCAYCARTAYGAYAAYYTNYTNTTYTTYTTYTGYTTY ATGTAYAAYAARATHCAYMGNAGYAAYGCN------------------------------ ------------------------------------------------------------ ------YTNTTYTAYGCNATGGGNYTNGCNYTNGTNATGGARGGNYTNATGAGYAGYTGY TAYCANGTNTGYCCNAAYTAYTCNAAYTTYCARTTYGAYACNTCNTTYATGTAYATHATH GCNTGYYTNTGYATGYTNAARATHTAYCARACNMGNCAYCCNGAYATHAAYGCNAARGCN CAYACNGCNTAYTTYTCNATGGCNGTNATHATHGTNATHGCNGTNTTYGGNGTNGTNTAY GGNACNAGYGTNYTNTGGATHTTYTAYGCNYTNGTNCAYATGYTNGCNACNYTNGTNYTN TCNGCNCARYTNTAYTAYATGGGNMGNTGGMGNATHGAYMGNCAYATHTTYAARMGNTTY TAYYTNYTNATHATHTCNGAYTGYATGMGNTGYTCNMGNCCNGTNTAYCCNAAYMGNTTY GTNYTNYTNYTNATHGGNAAYATHATHAAYTGGGCNTTYGCNYTNTAYGGNGCNATHACN CARCCNTCNGAYTTYGCNTCNTAYYTNYTNGCNATHTTYATHGGNAAYYTNYTNYTNTAY TGYATGTTYTAYATGACNATGAARYTNATHAAYAARGARMGNATHAAYTGGYTNGTNATH YTNGTNATHGTNGCNGCNGTNATHTGYTGGGGNGGNGCNYTNTCNTTYTTYTTYCARCAY YTNACNTCNTGGCARGARACNCCNGCNGGNTCNMGNGARGGNAAYAARAARTGYATHGTN ------------------------------------------------------------ ------------------------------------------------------------ ---------GAYTCNMGNGCNGARGCNGCNCCNGTNGTNCCNGTN---GTNACNGARCAR GAYGARAARCCNACNGAYGGNMGNAGYAGYCCNGAYGTNCARGARGAYAARGCNGARMGN GGNGARGAYMGNGCNGARGARCCNGCNCCNGARGGNTCNGARGAYTGYMGNGGNCARGGN AAYTGGAARTCNGCNGARCARCARGAYATGGCNGCNGCNATHATGGTNCARAARAGYGAY ------------AARGARGCNYTNGAYGARATGAAYGARGTNMGNGCNGARTAYGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GARACNAARGTNAARGAYYTNCARGARMGN ATGGCNGTNYTNGCNMGNGARAGYGARGCNAARGAYAARMGNATHYTNCARYTNGARGGN GAYYTNAARGAYGTNACNGAYAARYTNMGNGARACNGARMGNAARYTNGTNGCNTCNGAR GCN---AAYGCNAAYAAYTCNGARGCNCCNAARTCNAARACNTGYACNATHATG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNTTYAARAGYAAYGTNAGY GTNGARGCNYTNTAYCCNTCNAGYAAYCCNGAYATHYTNMGNCARGTN---CARAAYCAR GAYTCNAAYGAYMGNCARGARACNTTYGGNGGNCAYGTNCCNGTNGAYGARYTNGARATH ACNAARTCNMGNAGYAGYGGNCCNGGNGGNCARCAYGCNAAYAARGTNAAYAGYAARGTN GARATHMGNTTYCAYYTNAARACNGCNTCNTGGATHCCNGAYTGGATHAARCCNMGNYTN GCNGARCARGARMGNAGYMGNYTNACNAARGAYGGNATGTTYGTNGTNAARTCNGAYATG ACNMGNAARGCNATGYTNAAYCARGCNGAYTGYYTNAAYAARYTNMGNAGYATGATHCAY AARTCNTCNGTNYTNCCNAGYCCNCCNACNGARGARGARATHAARYTNAARGARMGNMGN ATGTCNAARGCNAARGARCARGTNYTNMGNGARAARMGNAAYMGNTCNYTNYTNAARAAR TCNMGNTCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TAYCAYCARGCNGTNTGYCCNTCNAAYCCNGAR TCNACNACNTCNATGYTNTAYGAYGTNMGNAARTCNTTYMGNAAYGTNATGGTNGCNAAY GGNTCNTCNTGGCARGGNTGGTGGAAYGCNGAYTTYAGYCCNACNYTNYTNGCNMGNGTN TGGGCNATGGTNTCNTGYAARGCNAARGGNAGYGGNCARGARAAYGAYGGNCCNMGNMGN ACNACNMGNGARTGGGGNGCNGCNMGNGCNGAYYTNCARAARTAYTCNCCNTGYMGNAAR GCNATGACNGCNGAYGCNATHCCNAAYATGTAYGAYYTNATGGTNAAYATHTTYAARMGN TCNAARTTYATHMGNYTNGAYATGAAYMGNGARGARTTYAAYACNMGNTAYTCNCARATH GCNAAYAAYTTYATHCARTTYCAYGAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AAYATHCAYGARGARYTNCAYCARCCNGARGCNAARYTNYTNAGY GARATHGARCAYGAYGAYCCNGARYTNMGNTCNGARGCNAARGCNGTNAARYTNGARACN GGNGGNAGYYTNTAYAGYAGYACNGARTCNATHAAYAARGTNGCNACNGAYTTYAARGAR ATHCARTTYGARGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNGARATGGAYCCNGARYTNCARGTNATGGCNAGYATHACNGAYCAYYTNATH TCNACNYTNGCNAAYTAYYTNCAYTAYAARGAYGTNAARACNGTNTCNTCNTGYGAYAAR AARGARATGGAYTGGGGNAGYGARATGAARMGNGTNGCNTTYYTNGTNTTYGCNTCNATH AGYGCNAAYGAYGARGAYATHMGNGARAARGTNATHAARCARGAYGGNATGGTNGARCAY ATHCARGCNTCNTTYATHAGYACNAAYCARGCNGARGTNGCNGCNAGYYTNMGNTGYYTN CARTCNYTNACNMGNTCNGTNCARCARATHMGNACNGTNYTNCAYGAYAAYGCNATGTGG MGNCCNYTNYTNCARATGGTNMGNTCNCCN---------------AAYMGNGAYATHATG ATHYTNGCNATGGCNTGYATGTGYAAYYTNGTNYTNGARTTYAGYCCNAGYAARGARGCN YTNGCNCARTGYAARGCNGTNGAYGTNTTYTGYGARYTNTGYCARAGYCCNGAYAAYACN ATHMGNYTNAAYGCNACNTGGGGNGTNATGTCNATGTCNTAYTGYGCNTCNGAYGAYATG CARAAYAGYYTNATHGAYAARYTNGGNMGNGGNATGATHGTNAARYTNATHCARGAYCCN GTNYTNYTNATHMGNGARAARGCNYTNGGNATHGTNMGNAAYYTNYTNACNAAYAARGAR CAYATHGAYGGNATGGTNAGYGAYYTNGGNCCNGARGTNATHGAYTCNGTNTTYGGNATH ATHMGNGAYGGNGAYATGCCNYTNGARGTNYTNGARCARGGNYTNTGYACNYTNAGYAAY ATGTCNGAYGGNCCNTCNTGYAARGCNCAYATHATHGGNAAYACNGAYAARATHATGGCN GCNGTNAAYTTYYTNAARCAYCCNGARAARMGNYTNATGYTNCCNGCNATHCARTTYGTN AGYAAYYTNGTNGAYCCNTGYGAYGAYGAYGGNGGNTCNTTYCCNMGNGCNGGNTCNTAY CARMGNATGYTNGARYTNAARAARYTNGGNGTNCARACNATGYTNGARAGYYTNGTNGGN ACNAGYCCNACNGAYGTNGAYATHMGNGCNCARCARGCNYTNAARTGYTTYGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GCNGARAARAARMGNATHYTNGARGARGARAAYAARCARYTNCARAARYTNAARGCNGCN GAYGARACNGARCARMGNYTNAARGARGCNTCNTCNCCNCARAAR---CARCCNCCNGCN ACNAAYAAYCCNTTYGCNGCNAGYTCNCCNAGYTCNTCNATHGGNCARTCNAAYYTNYTN GGNTCNCCNACNGARCCNACN---GGNGCNAGYMGNCCNAGYGAYGAYYTNYTNAAYYTN GCNAAYAAYCCNTTYATGGAYAAY------------ATGGGNAAYGCNGGNGGNTTYCCN GCNCARCCNGCN---CCNAAYCCNTTYGGNTCNCCNGGNTTYCARACNAAYGGNATHAGY GGNACNGCNGGNGGNTTYACNTCNGARGCNGAYTTYGCNAARGCNTTYAGYAAYGGNTCN TCNAAYACNCARNNNGGNTCNGGNTTYGGNACNACNYTNACNATGGCNCCNACNTCNAGY TTYGAYGCNTTYGGNGAYGTNYTNYTNCCNGGNAAYAARTCNCCNTCNCAYCARTCNCAR GCNAAYCCNCARGCNAARCARYTNGGNGGNGAYYTNGAYTCNTCNYTNGCNTCNATHGCN ACNAAYYTNAAYGTNAGYGGNGGNGCNGGNCARYTNAARAARGAYCAYCARTGGCARCCN AARGGNGARAAYAARYTNACNGGNGGNAAYGCNTTYCARMGNCARCCNATHGCNCARTCN ACNACN------------ACNACNTGGGGNCARACNGGNTTYCARCARCCNACNCCNATG ATGGGNGCNGCNCCNGGNGCNCCNATGATGTAYAAYCARGCNATGACNGGNATGACNCCN ------------CARCCN------ATGATGGGNATGGCNCCNCARCCNATGGGNATGCCN ---ATGCARCCNGGNATGGCNCCNATGCCNATGCARCARCCN------------------ ------------------------------------------------------------ ---AARTCNCAYYTNGTNCCNTGGYTNAARGARGTNATHAARAARTGYCCNGGNGTNGTN TGGCAYAAYCARYTNAARGARACNTTYMGNATHCCNTGGATHCAYTTYMGNAAYAAYGAY TGGTCNMGNTGYTAYTCNAAYGTNTTYAARGARTGGGCNMGNGTNACNAAYAARTAYAAR GAYGGNGAYATHGARGARTGGCCNAARTGGAARGGNCARYTNMGNTGYGCNYTNAAYAAR GGNAAYGGNATHTGYGARATHGTNTCNYTN---MGNAGYTCNGAYATHAARCCNTAYMGN GTNTAYCARTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNCARCCNCCNMGNCAYGGN MGN---MGNAGYGAYGTNGGNCCNCCNCCNGAYCCNTCNTTYAAYCCNYTNGCNGAYMGN MGNMGN------------GGNGCNGARAARAAR------------GAR---GGNCCNGAY CARAARMGNCAYCCNMGNAAYTAYGGNGGNGGNGCNGAYYTNTCNMGNGTNAARGARACN ATGAARACNATGMGNGARAARGARAARGAYMGNCCNCCNTCNACNAARCARYTNGARATG ATHATGACNGGNAARGARMGNAARAAYCAYCARGARTGGAARGTNGARMGNGARMGNTAY GAYAARGARMGNATHCARMGNCARYTNAAYGARGCNGGNAGYTGGAARMGNGARTGGGAY AAYGAYAARATHAGYYTNGARTAYGAYGAYGGN---------AAYTCNAARTTYGARCCN GCNAARMGNCCNGCNGGNMGNATHGGNAGYGGNMGNTTYGAYMGNGGNGARMGNGARGAY MGNCCNMGNGCNTCNGGNMGNGARGGNAARGGNGGN------------------------ ---------------------------------------------------------TCN CARCCNCARCARCCNCAYCARCARTCNCARCCNCARCARCAYCAR---CCNACNAAYGCN CARCCNCARGCNTCNCCNGAYYTNAARTCNMGNGGNMGNGGNAARGGNMGNGGNMGNGGN MGNGGNAAR------GGNGCNGGNAAYGCNGGNCCNGGN---GARAARTCNCCNMGNCCN MGNACNTGGTCNGGNGGNGAYGAYMGNTTYGTNGARTGYCARAARGARATGYTNGTNGTN AARTTYGARAAYACNGCNGGNGAYAAYACNGTNGARGTNGARTAYGARAAYGARGARCCN GTNTCNCCNCCNTCNACNCCNAARTCNACNTCNACNACNCCNGGNMGNGGNCCNACNGGN MGNACNCCNAAYCARGCNGGN------------AARGGNAARGGNAGYAARCARCARCAR CCNAARCARCCNAARGGNGGNAARGGNMGNGGNAARCCNCAYCCNCARCAYCCNGGNCCN GAYCARTTYGTNGAYGCNGAYTGGGAYGCNAGYAAYGAYACNCARATGGCNTAYGGNCCN TCNMGNGAYGCNMGNGTNMGN---ACNTCNTCNCAYTCNCARAGYTAYGGNGAYAGYGAR GARTGGGARGAYTGYACNGARTCNTCNGGNATGGTNGAYGARGARGARCAYTCNGGNTCN GCNAGYCARCARAAYAAYYTNCAYGTNGARTGYCARYTNAAYCCNGARGCNCCNGARTTY YTNCCNACNTCNCCNGAYTTYATGAARACNCCNCCNGGNCAYGTNAARGTNATGAAYTGG TCNGCNGAYAAYAAYTCNCCNMGNTCNATGTCNAGYAARAGYTCNGTNACNTCNCCNMGN GTNGTNGCNCCNCAR--------------------------------------------- ---------------TCNCCNGTNTCNTCNGTNGARTCNTCNGTNTCNACNCAYGCNGCN AARYTNMGNGARCARTGYGAYGAYATGCCNGARGGNGAYCARCCNCAYCCNCCNCCNTTY ATHYTNGARGCNGARGCN------------------------------------------ ------------------------------------------------------------ ---------------------------CARACNGGNMGNAARGTNTCNATHAGYMGNCCN GCNAARGARCAYACNTTYYTNACNGAYGTNGCNGAYGTNMGNMGNATGGARCAYGGNYTN YTNACNYTNYTNAAYGAYTTYCAYTCNGGNAARYTNCARGCNTTYGGNAGYAAYGTNACN TTYAAYAARATGGAYGCNATHMGNGTNCARCARGARCARYTNGCNAARCARCAYTTYGAR YTNGAYYTNYTNCCNMGNACN--------------------------------------- ---------------------------------TGYAAYYTNYTNGTNATGTCNAARATH AAYGTNACNATHAARGTNATHTGYGCNATHAAYAAYCARAARCAYATHGTNACNCCNGAR TAYYTNGARCAYYTNCAYGCNCAYYTNYTNGGNMGNGARAARCCNAAYCCNYTNCARTAY YTNCCNGARATHGTNGAYAARAARGTNCCNCCNGGNGTNTCNTTYCAYCCNGAYACNAAR MGNYTNTCNYTNYTNAGYGAYYTNCARTTYTAYTTYYTNTCNGCNGTNCARTTYAARCAR ACNAAYYTNGCNATHTCNACNGCNGGNGGNYTNCCNATHYTNYTNGARGAYGGNACNGAR GARGAYATHGARACNATGGGNAARGAYGGNACNATHGTNGTNTCNGTNACNCCNGARGTN YTNGCNAGYYTNAGYCCNGTNTGYCARAAYTTYGTNAGYYTNGTNTCNGCNATGYTNGCN MGNAARAARYTNMGNATGGTNACNGAYCCNGARATHGGNTGGGCNATHYTNACNTGYAAY ACNGAYGAYTTYTGYAAYCCNAARTCNACNATHGTNAARGTNGTNGAYYTNGTNGCNAAY CCNTCNAARAARAARAARAARACNTCNYTNGCNGARYTNGAYGTNCARAAYTTYAARAAR TTYCARAARACNCARCAYGCNMGNTCNAGYTCNATGCCNACNATHATHGGNGGNAGYGAY YTNGARGCNTAYYTNGGNGAYAARCAYAARAAYATHCARGAYYTNTTYAGYCARACNMGN ACNCARCARGARGARCARGAYGARGARAARYTNTTYTCNTGG------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHGAYTCNGCNGGNCCNMGNTCNGARCCNGTNTAYYTNMGNMGNGAR AARCARGTNCCNCCNAGYYTNGTNGCNCCNAARCAYCCNCAYGGNAAYAGYCCNAGYATG GGNGTNCAYCCNCARGTNGGNCARCARMGNCCNGTNMGNCAYGGNAAYGAYAAYAGYAGY AAYAAYMGNCARTCNMGNACNCARACNACNMGNCCNGAYCCNATHCCNGGNCARCCNTAY GCNGGNGCNCCNGCNCARMGNGTNGGNAGYGCNCCNYTNMGNAARATHGGNGCNGGNCAR ACNCCNGCNATHMGNGGNAAYGGNACNGTNGCNAAYAARTCNNNNGARCCNGGNGARACN GGNYTNGARNNNNNNNNNNNNAGYCCNTTYATGMGNCCNMGNTCNMGNTTYGGNGCNGGN NNNNNNCANNNNNNNNNNNNNNNNCAYCCNGAYTTYYTNCCNCCNATGCCNMGNCCNCCN CARGCNTCNGGNGAYGAYGAYAGYATHATHGAYCARACNMGNCARATGACNACNGTNCAR GARYTNGARMGNCARTTYCARGCNYTNTCNYTNCCNCARGCNCAYGGNMGNCCNGAYATH GGNCAYCCNTCNAARAARYTNTGGGAYGAYGAYCCNCAYAARGCNGGNGAYGGNCARGCN AARGGNATGTTYCAYCAYGGNTGGACNACNMGNGAYGAYGCNTGGGCNAAYGCNGCNACN GARGCNAGYAAYCARATHGGNGTNAAYATHGCNGAR---TAYGTNYTNGGNGGNTCNCCN AAYAARGTNGAYCCNGGNGTNYTNMGNGGNATGAARCCNTAYGARGARAARAARAGYAAR ACNCCNTCNCCNTTYGARGAYTCNGGNGAYGAYGCNAARGAYTCNYTNCARGCNAAYGGN ATGYTNCCNAAYGGNYTNGAYGAYGCNGGNTAYMGNGGNAGYMGNCARACNTCNCCNGCN GAYGARGARMGNCARGGNCCNGTNGGNATGCCNYTNGAYCCNCARAARYTNCAYYTNMGN GAYGGNGGNGAYTTYYTNGAYAAYGGNCAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGAGYTCN TCNGTNGGNACNATGMGNGCNGGNTCNAAYAARCAYTCNGGNCCNAARGARAAR---ACN AARAAYGARMGNGGNTCN---CARTCNCARCARTCNTCNGGNAARGGNGAYAGYCARACN AAYAARGTNCARCCNACNCARGARCARATHMGNYTNGCNGARATGATGAAYACNAAYCAR ACNGAYGCNGAYGTNACNACNATHAARGCNYTNGTNGARYTNACNGGNAARAGYGARGAY GTNGTNGTNATHGCNYTNCAYGAYGCNGAYAAYGAYGCNGAYMGNGCNGTNATGATGYTN YTNGARGGNAAYGARCARCAYGGNGARTGGAARGARCARGGNGGNAARMGNAARAARAAR ACNTCNTCNCARAARGARAAYTCNAAYCAYGTNAAYGAYGAYMGNCAYGARGGNMGNAAY AARGAYAARGGNGAYGAYAARGARAARGAYGGNGGNAAYGAYMGNCARGAYGGNTCNTCN MGNMGNGGNMGNMGNAAYGGNGGNCCNCCNCCNMGNYTNGCNMGNGGNMGNGGNMGNGAY MGNGGNAAYTTYGGNGAYMGNGAR------AARGARMGNAAYAAYACNGARGAYTGGGAY AAYGARAARGARGAY------------------GARMGNMGNGAYAARACNGGNGGNGAY MGNGGNMGNTCNMGNGGNMGNGGNGGNTTY---GCNMGNMGNACNGGNGGN--------- GGNAGYMGNGGNGGNMGNTTYAAYAAYAGYGGNGAYMGNGAYAAYMGNAGYTAYAAYMGN GTNCCNMGNTTYGARAARATGAAYAAYCCNCARCCNATHGAYGGN------CCNGARATH GAYACNTGGACNAAYGARACNGCNGARAARAAR---CCNAGYAARGAYACNGAYTGGAAY AAYTGGAAYGAYACNTGGGTNATGGAYGARGAYCARTGGACNGGNACNYTNGARGARACN AARGTNTTYACNCCNTCNCARATGAARATHCCNGARCCNGARCCNGTNATHTCNGARCCN CCNAGYTCNYTNGGNCARMGNYTNGAYGTNGGNAGYYTNTTYGARTCNGCNAARTTYTCN AARGCNCCNGAYTAYTCNAARCCNAGYGGNGAYTCNTAYATHACNCARTTYAAYCARGCN GCNACNGARTCNATHAARAAYACNATHGGNATHGGNAGYTCNTCNMGNCARGCNYTNTCN ATGTCN---------------CARCARTCNACNACNAAYGCNYTNGGNYTNTCNAGYYTN GCNCAR---------------CARCAYAGYAGYGTNYTNTCNTCNYTNCARCARCAR--- ---------------TCNGCNTCNCARGCNATHACNCARATGTCNCARATHGCNCAR--- ---------------------TCN------------------------GCNTCNCARGCN CARGCNATGTCNCAR---------ATHGGNATGGGNAGYCARCARGCNCARGTNAAYAAY AAYCARGCNCCNGCNCARTCNMGNATHCCNTCNATHATGCARCARCARAGYYTNCAR--- ---------------CCNCARACNGGNATGAAYACNAGYATGTCNCAYMGNCCNAARTCN CARMGNTCNAARYTNCCNCCNCCNTCNAARATHCCNTCNTCNGCNGTNGARATGCCNGGN CAYATHCCNMGNAAYCCNCARYTNGAYYTNCARTTYGGNATHGAYTTYAGYTCNGARCCN ACNGCNACNTTYGGNTTYGGNGGNAGYGGNGAYAGYGTNGCNGCNACNTCNTCNTAYTCN TCNACNTCNAAYGGNACNTCNTCNGTNATHTCNAGYCAYYTNAGYCARGGNYTNGTNAGY CARACNGARAGYGARACNGARCCNATHTCNAAYATGATHTCNTCNCCNCARGCNGGNTCN GGNAARGGNCCNTCNGGNATHGARAAYCARGCNCCNAAYMGNCCNCCNGGNGTNTTYCAY AAYTCNGTNTAYCCNGTNTCNCCNTCNAARAAYGAYACNCARAAYYTN------GARCAR AAYAARYTNAGYGAYGCNATHCCNTTYCCNCCNTCNCARYTNGARMGNAARTCNAGYCCN ---YTNTCNTCNCARMGNACNGGNCARCCNAAYCARAAYYTNAGYTCNGGNTCNYTNCCN CCNAGYAARGAYTCNTCNTCN------------------AAYTAYACNACNGCNAAYGGN TAY---GCNTCNTCNTAYCCNACNCAYCARAARGCNTCN------TCNTTYACNCAYTCN TCNAAYCCNCARGCNCCNCARAGYTCNTCNTTYCCNGGNCARTAYCCNGCNAGYCARCCN ACNTAYCCNGGNTCNGGNCARTCNCARTTYTCNGCNCCNCCNAGYGCNTCNCARTTYCCN TCNTCNGGN---------CARTAY---------AAYAAY------GTNCARAAYCARTAY TCNGCNGGNCARAAYCARTTYCCNTCNGGNAAYTCNACNYTNCCN---------CAYCAR TCNCARTAYTCNGGN---ACNCARAGYTCNTAYGGNAGYAGYGGNCARTCNCARTAYTCN GGNTAYCARAAYAAYAGYTCNTTYTCNTCNCAYCCNCCNTCNCARTCNAAYTTYTCNTCN AGYCARACNGGNGGNTCNAAYAAYACNATGTAYCCNTCNACNTCNCARTCNGGNGTNTCN TCNTAYACNTCNCARTCNAAYTCNTAYCARTCNCCNTCNGCNGGNTCNTAYCAY---TCN MGNGAYACNCCNGCNAGYGTNACNGTNACNACNCARTCNAGYAGYGGNGTNAGYTTYCCN AAYCARCARGTNTCNTCNTCNYTNAARCCNGTNAGYACNCARAGYAAYACNATHTAYTCN TCNCCNGGNTTYAAYGCNAAYACNGCNCCNYTNCARCCNCCNCCNYTNGCNAAYAARYTN GGNGAYAGYYTNTCNAARATHACNYTNAARGARAAYAAYTCN---YTNGAYGGNCAYCAR ACNAAYCARTTYGARCAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ACNYTNGCNYTNGTNATHYTNGGNAARYTNAAYAGYGARATGATHYTNTTYTCNGAYATG YTNGARYTNGTNTAYGTNGGNATHGAYYTNTTYGCNTTYTTYYTNACNTTYATHGGNGCN TGYATHYTNTCNGCNGGNACNAAYTCNACNTGYTCNCCNGTNGTNTGYAAYAAYAAYGAY TGG---------YTNTCNTCNTCNMGNGCNGCNCARGCNGGNGCNTGGATHAGYACNTTY GTNTGGATHTTYGTNGGNYTNTGYGGNTTYYTNTGYYTNTGGMGNGARGGNAARATHCCN TTYYTNGGNGGNAAYACNGGNTCNACNGCNCCNGGNACNACNGGNTCNCCNACNGARGAR GGNCCNCCNATHGAYACNCCNCCNAGYAAYCCNGAYGTNTAYAAYAARTAYATHTCNTAY YTNAGYCCNAGYGGNGCNYTNYTNACNTCNYTNAGYGARATHMGNGAYTAYYTNYTNAGY GAYGAYACNTGYAARTGYGGNYTNGARTGYCCNATHCARYTNGAYAARGCNTTYAGYTTY GAYACNAARGTNGARAAYCARCCNTGGAGY------------------------------ ------------------------------------------------------------ ---------------------------------------------AGYATGGAYGCNACN YTNMGNAARMGNATHTTYAAYGGNYTNAGYTGY--------------------------- GGNGTNAAYGCNGGNGTNGARTCNCCNTCNYTNCCNTTYACNGARYTNTCNGTNAARTAY TTYCARGARGAYATH------CCNMGNTCNTTYGARGAYATHGAYATGCARACNGCNTCN AARYTNACNMGNMGNAAYGARGTNTCNCCNTGYTCNATGGTNYTNTCNYTNYTNTAYGCN AARMGNYTNAARCARMGNAAYCARGARTAYYTNCARTCNATGTCNTCNACNAAYGTNTTY TTYATHTCNATGATGATGGCNAGYAARTAYYTNTAYGAYGARGGNGTNGARGARGARGTN TAYAAYGAYGAYTGGGCNGAYAGYYTNGAYCARGAYGTNGAYGARGTNAAYAARATGGAR ATGGAYTTYYTNAARGCNATGGAYTGGMGNYTNTTYGTNGGNCARGARGARTTYGARGAY GCNATHTCNGCNATHGARMGNMGNYTNGCNATGCARGARGGNATHAARMGNGGNTGGTTY ACNTAYTCNGARYTNTCNYTNYTNYTNAAYYTNGAYYTNCARAAYATHYTNTGGGGNGAR YTNGGNYTNGAYTGYACNAARTTYYTNGCNGTNYTNTCNACNGGNTAYYTNATGGGNTTY YTNAGYYTNYTNGGNTCNGCNACNGTNGCNATGCARGTNTCNGTNCCNGTNACNACNGCN ACNYTNGCNYTNYTNTCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TGGTTYTTYTAYAARTTYATHAAYCCNTGGYTN TCNAARYTNTGGAAYMGNTCNGAR---TAYGTNACNAGYAAYYTNACNTGYCCNYTNCCN CARAARAARAAR------------------------------------------------ ---------------ATGTCNAAYGCNGGNTTYTTYMGNGGNACNACNGCNCARCARGAY ACNMGNTTYTCNGAYAARAARAARAARYTNATGMGNACNATGAARTTYGGNGARGGNYTN GARMGNAARGTNGAYATGACNAARGTNAAYGTNGAYAGYATHAARCCNTGGATHGCNCAR MGNATHACNAAYYTNYTNGGNATGGARGAYGAYGTNGTNGTNGARTTYGTNTAYAAYCAR YTNGAYGARMGNCAYCCNGAYGCNAARGARATGCARATHAAYYTNACNGGNTTYYTNAAY GGNAARAAYGCNMGNATHTTYYTNTCNGARYTNTGGGAYCAYYTNTGYAGYGCNCARGAR AAYGTNACNGGNATHCCNAAYCARTTYYTNGARCARAARAARAAYGARATHAARCARMGN CARGARGARCARGARMGNYTNCARGARGCNYTNAARAARAARGARGARCARATHAARGAR CARYTNGCNAARGARMGNMGNGARATG--------------------------------- GARAARMGNGAYYTNAAYAAYYTNTCNCCNGAYMGNCCNGTNAARCCNGGNAARCCNGTN ACNGCNGARGGNGAYGCNAARAAYGGNCAYGCNGAYATHAARGCNGARCCNAARGARGGN GARGCNGARAGYACNGGNCARGARGARAGYGARTCNAARGGNAARCCNGAR---GTNAAR AARGAYGARGCNGCNAARTCNGARCCNGAYMGNAARGARAARTCNCCNAGYMGNAARAAY MGNGAYMGNGAYMGNGAYMGNMGNCAYMGNTCNMGNACNCCNGAYMGNCAYTCNAARYTN TCNTCNMGNGGNCCNGAYMGNCAYMGNMGNGAYMGNGARMGNGARMGNGCNCCNATGGGN MGNMGNMGNTAYTCN------CCNCCNMGNMGNMGNTCNMGNTCNCCNMGNMGNTCNMGN TCNCCNMGNMGNMGNTCNCCNCCNCCNMGNAARMGNTCNCCN------------------ ------MGNMGNACNCCNACN------CCNAARMGNGARTCNMGNTCNCCNMGNAARGGN ATGGARCARAARAARAAR------TCNMGNTCNAGYAGYGARAGYAGYTCNAGYGGNTCN GARGAYGAYAAR------------TCNAAYGAYGGNACNTCNCCNGARAARGGNGGNATH CARCARMGNMGNAAYTAYMGNAARCAYGARGAR---AGYGGNAARGARTCNTCNTCNTCN GAYTCNTCNGARGAYGARCARAARMGNTCNCCNTCNGCNCCN------------ACNAAR CAYGTN------------GARMGNMGNMGNACNCCNTCNCCNTTYATGMGNMGN------ ---CAYMGNACNCCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNTTYYTNGAYCCNAAYCAYTCNCAYTTYATHYTNTTYACNGTNGARATH CCNTTYMGNGCNAARYTNGAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYGARYTNAAYATHYTNYTNGTNGGNTCNGGNGAYYTNMGNCAYATHYTNAAR ACNGTNGCNCAYMGNTAYMGNCAYACNAARMGNAARATHAARTTYTAYATHGTNGARTCN GCNYTNGARYTNTAYYTNMGNGAYATHATGYTNATGATGGTNGCNYTNGARAARCCNCAR AAYATGGGNYTNCARGARAARACNCARYTNTTYYTNGARATGTAYGGNAAYACNYTNATH MGNCARCARGCNAGYCARTAYATHGARAARATGGCNCAYCARATGATHCARATGGTNACN GAYTTYGAYTAYYTNAGYAARAARYTNTCNYTNTTYGAYYTNAGYCARYTNAARTAYAAR GARMGNGAYTTYYTNGARGGNGTNYTNAARTAYTGGMGNAAYMGNGAY------AARGCN ACNTTYGARGTNGTNAARTGYTGGGAYATHMGNYTNMGNCARCAYYTNGGNGTNMGNTAY GAYAGYMGNATGAAYGCNTTYGAYTGGGAYTAYAAYATGGCNYTNATGGARMGNGGNGGN TCNATHGTNCAYATGAARCARTAYAARGGNTGGMGNAGYGAYGGNATHGCNTAYACNATH MGNGAYGGNACNTAYGAYGTNCCNAAYMGNATGYTNTCNTCNGCNACNGTNTTYMGNCAY GARGGNGARMGNCAYCCNMGNMGNGGNTAYTGGGGNGAYATGGTNGTNTCNCCNTAYATH ACNTTYGGNATHGARACNGARGARAARTCNTTYTAYCARAARMGNAAYAAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TAYAAYGGN GTNAAYAAYTAYACNCCNACNMGNAGYCAYACNGGNATGCARGAYGGNAARYTNTTYTTY GARTGGCCNTAYACNCCNGTNTAYMGNGGN------------------------------ ---TTYCARAGYCAYTTYGGNTAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TAYCARGGNMGNGARGAY---------------TAYTAYGAYCAYACNTAYGAR--- ------------------------------GCNGAYYTNTCNCAR--------------- TGGGGNYTNGAYTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYTCNYTNGGNGTNTCN MGNCCNMGNGGNGTNTCNYTNGARAARGCNTCNTTYTAYGARAAYCCNACNGARTTYACN TGYTTYTCNGAYGGNATHAARATHCCNAARGAYTAYGTNAAYGAYGAYTAYTGYGAYTGY GARGAYGGNTCNGAYGARCCNGGNACNTCNGCNTGY---AAYGGNYTNTTYTAYTGYGAR AAYAARGCNCAYGTNGGNACNTAYATHMGNTCNTCNMGNGTNGAYGAYGGNYTNTGYGAY TGYTGYGAYGGNTCNGAYGARAGYGAYGCN------GCNTGYGARAAYACNTGYGARCAR YTNAAYGTNAARGCNMGNGCNCARCARGARGCNATGMGNGARMGNCARGARAARGGNTAY AARYTNAARYTNGARYTNATHCARCARGGNAARMGNAGYAARGAYGARAARYTNTCNMGN YTNAAYAGYYTNGARCARGARAARTCNGCNYTNGARAAYGARAARAARAAYATGGARAAY ACNAARAAYGARGCNGARATHCCNGARAARGARGCNATHGARAARCAYAARCARGCNTGG GARGCNGTNAARGCNGARAARGARAARGTNAARGAYGCNGARACNGCNGGNAAYGCNTTY ACNGTNYTNGAYGTNAAYGGNGAYGGNAARGTNGAYTTYCCNGARATHATGAARCAYATH GARTTYGAYATHGAYTCNGAYGGNACNGTNAGYGARGARGARGCNAARGARTAYYTNGAR GAYTAYGARGAYGTNGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYGGNCARTGYGTNCARGGNTCNGTNACNMGNAARYTNTAYYTNGGNGAYGTN CARGCNTCNMGNGGNCCNGGNATHTAYTTYTGYMGNGTNTCNACNMGNGAYCARGGNYTN TTYACNMGNGARGCNATHGTNCARYTN------------TAYMGNCCNCCNACNGAYACN GARTAYGTNGCNGTNGAYAARGTNGCNYTNYTNATHGGNGCNTTYGAYTAYMGNAGYGAR ACNGARYTNAARGCNCCNCCNCARGAYGTNGARAAYYTNGCNAAYGTNTTYMGNAGYYTN AAYTTYAARGTNATGTCNTTYYTNAAYYTNTCNAARATGGARATGGARAARGTNGTNGAR GARTTYAARCARYTNATHGGNCCNGGNGTNTAYTGYGTNTTYTAYTTYAGYGGNCAYGGN TTYGARGCNAAYGAR---TGYTTYYTNATHCCNCCNGAYGCNCCNCAYGGNTAYAAYAGY GAYAARTGYGTNTCNGCNAGYAARATH---YTNAGYATGYTNCARGAYAARGARCCNAAR ATGTGYTGYATGATHYTNGAYATHTGYMGNAARAARAARGGNGARTCNCCNCCNGARATH YTNCAYCAYAARCCNTCNGAR---GGNAAYACNATHATHYTNTAYGGNACNYTNAGYGGN YTNAAYTCNTAYGARCAYGARGGNAAYGGNATHYTNGTNAGYCAYYTNAARGGNCCNATH ATHYTNCCNATHCCNGTNGARGARGTNTTYGCNMGNYTNMGNGARAGYYTNGCNAAYGAY CCNTCNTTYAARGARGARGAYGCN------------GTNCARAARCCNGARATHMGNACN GCNYTNGAYGARCCNMGNMGNTCNTTYAARGAYMGNATHGAYGTNACNGGNCAYACNTCN ACNTGYATHGTNMGNCAYGGNATHTGG--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CAYMGNGCNATGMGNAGYMGNACNAAYYTNTTYYTNGTNAAY YTNGCNGTNGCNGAYTTYYTNGTNGGNYTNGTNGTNYTNCCNTTYTCNATHACNACNYTN ATHCARGGNAARTGGGTNTTYGGNGAYTTYATGTGYTCNYTNAAYGGNTGGATGAAYTGY TTYTGYYTNGTNACNTCNATHCAYACNYTNATGTAYATHGGNGTNCAYAARTAYTAYTCN ATHGTNCAYCCNATGAAYAAYCCNATHAARYTNAAYCAYATHTTYGGNATGATGTCNGCN GCNTGGATHTGGGGNGCNTTYTGYGCNACNATHTCNGTNACNGGNYTNAAYACNGTNGTN TAYAARTAYGGNACNTCNCARTGYGGNCCNMGNTAYCCNMGNGARATHAARAGYTTYATH TTYCAYGGNATHGTNCARGTNTCNGCNATHTTYATHCCNTTYGTNATHYTNGTNTAYTGY TAYATHMGNATGTTYMGNGARATHAARAARCAYTCNCARMGNYTNMGNGAYAAYACNACN GTNGARGAYGAYTTYATHATHAAYCARGARAARAARGTNYTNATGACNYTNTTYATHGTN YTNACNACNTTYGTNATGATGGCNYTNCCNTAYCAYATHTAYGCNACNTAYACNACNATH ACNAARGAYAARGARAAYTTYCCNGTNTAYATHAAYCCNYTNGCNTAYATGTTYYTNTAY YTNAAYTCNATGTGYAAYCCNATHATHTAYGCNTTYMGNTCNCCNGCNTTYMGNGARGGN TAYAARGARATHYTNTGYMGNACNCCNAGYTAYGTNGTNMGNGAY--------------- ---------------------------GAYGTNGARGCNATHGAYGGNYTNGARGCNAAY GAY---------AARGCNGCNYTNYTNGAYYTNTCNGAYAAYMGNATHACNGGNYTNAAR GGNYTNGARCARTTYCCNAGYATHGARACNYTNACNYTNGAYAAYAAYYTNYTNGARTCN GTNGARGGNATGCCNTGYYTNCCNAARYTNAARACNYTNTGGYTNAAYAARAAYAARATH GGNGAYCAYGAYGCNACNYTNGAYGTNYTNGCNAARCARGTNCCNCARYTNCARTAYYTN TCNYTNATGGGNAAYGAYTGYTGYAARTCNGARYTNTCNGGNAAYTCNAARGAYGARYTN GAR------MGNTAYMGNYTNTAYACNATHTAYMGNYTNCCNAGYYTNCARYTNYTNGAY TTYGCNCCNGTNYTNCCNGCNGARMGNGARAARGCNTCNTCNAARGGNCARTTYYTNAAR GTNTCNAARGCNAARGARCARGAY------------------------------------ ------------------------------GGNGAYGTNGGNTTYGAYGARMGNGARATH YTNMGNGAYGCNGAYAAYYTNGAYGAYGARYTNTAYAARTCNTCNGARYTN--------- AARGARGAYGAYAAYAARGTN---GCNGTNGARGARCCNCARGARAARGARAARCCNATG GAYATHGAYYTNCCNCCNCCNGTNGAYGARGAYGGNTTYGGNGGNGAYTTYATGGAYGCN GAYGAYGGNTGYGAYGARGAYAAYGAYAGYTTYGGNGAYGTNGAYCARGAYTTYTTYGGN CARGAYTTYATGGGNACNGGNGGNYTNTTYGARGAYCCNCCNGCNYTNGCNACNGTNGGN GAYGCNGARGARACNGGNGARGCNGCNTCNAARCCNGTNGARGARGGNCAYAARGCNCAR CCNGARGTNGARAGYGARGARACNYTNCCNYTNCARGCNTCNACNGCNGGNATHTCNGCN GTNTCNAGYACNGTNGGNGARCARACNACNYTNGTNCAYAAYGARGARGARGCNTTYGCN YTNGARCCNYTNGAYATHACNACNGTNCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GGNGTNGTNCARATHAAR ATGGARTTYATHGARAAYAARYTNMGNMGNTAYACNACNTTYAGYAARMGNAARACNGGN ATHATGAARAARGCNTAYGARYTNTCNACNYTNACNGGNACNCARGTNATGYTNYTNGTN GCNAGYGARACNGGNCAYGTNTAYACNTTYGCNACNMGNAARYTNCARCCNATGATHACN AGYGARAAYGGNAARGCNYTNATHCARACNTGYYTNAAYTCNCCNGAYACNGGNCCNGGN GGN---YTNTCNGGNAAYGCNYTNGARCARMGNATGAAYCCNTCNGGNTTYGARGARACN GARYTNTCNAGYGCNGTNGGNGARGARGARCARAARGTNGARAGYAGYGGNAAYYTNAAR GCNGTNTTYCCNCARGTNTCNCAYGTN--------------------------------- ------------------------------------------------------------ ------------------------------GTNACNCAYGTNMGNTAYATHATHCARYTN ATGTGYAARATHYTNAAYGARAAYGGNATHACNTCNATHCARGCNGARACNYTNMGNCAR GCNAARTTYAAYAAYCAYTCNGTNACNGARCARATGTGGGAYATHYTNTTYGARAGYTTY TGYTTYACNATHACNGARTCNYTNAARYTNTTYGTNAARTCNGCNYTNCARAAYYTNGGN TAYYTNAAYAARCARTTYGCNGARYTNCCNCCNGAYATGACNTTYGGNAGYMGNGARYTN YTNYTNGCNYTNGGNTGGATGTTYCARACNAGYGCNTTYTTYGARAARGTNATHTCNCAY MGNAARAGYCCNYTNGAYCARGAYYTNATGCAYTTYGAYGARCCNGARGTNGARTCNCAR CARGCNAARGARATGMGNCCNAARGAYTAYYTNCCNACNCARCARAARYTNCARCARCAR YTNATGYTNTGYGGNAARYTNMGNYTNTCNYTNMGNMGNYTNTAYTCNTCNCARCARCAR MGNGCNAARYTNMGNGARYTNATHCAYAARTCNACNAARGGNATHAAYATHCARAGYGAY YTNCARCAYYTNACNGCNYTNGARGTNCAYYTNYTNMGNTAYCCNAAYAGYYTNAARAAR ATGATGCARYTNYTNGARCARGAYAAYGTNMGNYTNAARAAYYTNGTNGARTGGAARGAR AAYGARCARGTNTTYTGGGAYTGGATGAAYAGYATHYTNACNYTNCAYATHCARGARMGN GAYAGYGGNAARYTNAGYCARAGYAAYAAYCCNGGNGARACNATHTTYATHAGYGTNCCN CCNACNYTNAAYGARGAYYTNGAYMGNGCNMGNTCNMGNYTNMGNGAYAARATHYTNAAR CAYGARGARGAYATHATGCARYTNGARAARYTNYTNMGNAARAARCARGTNACNTCNATH GARGTNGAYGCNGTNGCNATGACNGTNGARAARGARATHAARGARYTNACNGAYATGYTN ATGAAYTGYGGNACNGGN---ACNATGTCNTCNTGYTCNTCNACNTTYCCNGGNYTNTCN AARACNYTNTCNCARCCNYTNGGNCAYAAYGARGTNGAYGAYAARTCNMGNTTYAARAAY TTYGTNATGCARTCNGCNMGNGARATHCARGCNGGNAARCARGCNGARATHYTNCARGTN GTNAAYGAYGARATHCARAARYTNCARGCNAARGTNAARGARYTNGARTCNCARYTNMGN AAYCARCARYTNTCNAAYACNCAYAARATGTTYGCNACNTTYAAYGAYGAYATGAAYTGY ATHTGYATHYTNCCNMGNTGYTTYAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GAYGAYTTYTGYMGNYTNCCNYTNGAYTTYGCNAARGAYYTNGGNAAYGCNATHACN GGNATHACNGAYGGNTTYGAYGCNGARTTYYTNGCNAAYGARGARGCNTTYAARGCNGGN YTNGAYCCNYTNGAYATGGAYGARATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CAYYTNYTNYTNGCNAARYTNAARGAY ACNTGYGAYYTNGARAARGTNGAYTGGYTNTAYCCNGAYGGNGARCCNCARGARGTNGAY TGGYTN---ACNTGGACNGTNTTYACNCAYAARCCNTCNAARGARMGNATGAGYAARATH AAYGCNGCNYTNGAYTAYGARAGYATHYTNTGYYTNCCNAARAARGCNGARGGNGARAAR YTNCCNCCNYTNATHYTNTTYYTNCAYTGYGGNCCNAAYTCNGCNTTYGAYAAYTCNTTY CARTCNATHAGYAAYTTYTTYTGYTGYTGYGGNTAYGCNGTNYTNATGGTNAAYTAYMGN GGNTCNYTNGGNTTYGGNCARGAYAAYATHYTNTCNYTNTGYGGNGCNATHGGNGAYCAR GAYGTNAAYGAYTGYGARGCNGCNATGATGGARATHYTNGCNAARGGNAARGTNGAYCCN AAYMGNATHATGGTNTTYGGNGGNTCNCAYGGNGGNTTYYTNACNACNCAYYTNATHGGN CARTAYCCNGAYTCNTTYAARGCNGGNGCNTCNMGNAAYCCNGTNGTNGAYYTNGTNTCN ATGCAYGCNGTNACNGAYATHCCNGAYTGGACNTTYGCNCARGCNGGNYTNCCNTTYGAY TAYGAYAGYATHCCNGAYGARGARGTNYTNAARACNATGTGGAARGCNTCNCCNAARTTY TAYATHAAYCARGTNAAR------------------------------------------ ------------------------------------------------------------ ---------------ATGGGNGARGGNMGNGARAARACNGARGCNTTYGTNACNYTNGCN ACNAAYGAYACNTAYTCNYTNGGNAGYYTNGTNYTNGCNAAYTCNYTNMGNMGNGTNMGN ACNACNMGNCARYTNGTNATHATGATHAGYAAYGARGTNTCNCCNCCNATGMGNTTYCAR YTNGARGGNATHTTYGAYCARGTNGTNGTNGTNAAYGTNATGGAYAGYMGNGAYCAYTGY AAYYTNGAYYTNYTNGGNMGNCCNGAYYTNAGYTGYACNTTYACNAARATHCAYTGYTGG MGNYTNACNAAYTTYAARAARTGYGTNTTYATGGAYGCNGAYACNYTNGTNATHCARAAY ATHGAYGAYYTNTTYGAYMGNCARGARYTNTCNGCNGCNCCNGAYGCNGGNTGGCCNGAY TGYTTYAAYTCNGGNGTNTTYGTNTTYGARCCNTCNGARGARACNTAYAARAAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNGCNGAYYTNGGNGGNTCNCCN ACNYTNTTYGGNYTNGCNTCNGTNATHAAYCAYATHTCNGARYTNYTNGCNTAYTTYATG ACNGGNACNTTYATHGGNMGNTTYGGNCAYGTNMGNGTNYTNTAYGCNGGNYTNATHGGN AAYATHATHMGNTTYATGTAYATHTCNTTYYTNMGNAAYCCNTGGTGGGTNYTNCCNTTY GARTTYGTNCARGGNYTNACNCAYGCNGCNGTNTGGGCNGCNTGYTGYGCNTAYATHACN CAYGCNATHCCNGTNGARYTNMGNTCNTCNGCNCARGGNATHYTNCARGGNYTNGAYCAY GGNYTNGGNMGNGGNTGYGGNGCNGTNTTYGGNGGNYTNATG------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------MGNGAYAARATHAARTCNTGYYTNGAYGAYYTNAARGARCAY GTNCCNTCNYTNMGNAAYAARGGNAARATGAGYGARTCNGCNATHYTNTTYAARGCNGCN GARTTYATHCAYCARYTNAARGAYGGNAAYACNGARAAYGGNTGYAARACNGARGARYTN MGNCARGARATHCAYTGYYTNAGYGCNGARATHNNNTCNTTYCARGARAGYYTNCCNGCN GGNGGNYTNAARGARGARGCNATHTCNGGNYTNTCNYTNGAYGARATGTAYCARCARTGG GTNACNGCNCARAGYCARAARTCNACNAARTTYTAYATHTTYTCNACNATHATGCCNAAR YTNTTYGARTCNTTYAARGARATHGTNGGNCCNGCNACNAAYTTYTCNACNYTNGCNGCN MGNGTNAARGARTGGCARGARAARCAYYTNAGYYTNCCNGTNYTNMGNAARCARGTNTTY AAYGGNATGYTNTCNYTNACNMGNAARACNAGYATHYTNTCNTTYCCN------------ ------------------------------------------------------TGYGCN YTNCCNYTNTTYGGNGCNGCNTTYTGYGTNATHTGGTCNGTNYTNTTYGAYTTYGARTCN TCNACNMGNACNCAYTGYAARGTNCCNAAYTAYYTNCCNTCNGTNAGYTCNGGNGGNTTY GCNCCNCARAARTAYGTNTGGMGNATHTGYTTYTAYYTNCARCAYTAYCAYTGGTAYGGN TAYYTNAGYAAYCARACNMGNTCNTTYCCNATHACNGGNGTNAAYYTNACNCAYTCNTTY YTN--------------------------------------------------------- ------------------------------------------------------------ ---GAYGCNGAYYTNYTNCAYMGNTAYATHATHTGYACNAARAAYGCNGGNCAYGARAAR TTYATHGAYGCNAARGARATHACNYTNGAYGAYYTNCCNGARGCNYTNMGNCARCARGAR ATGYTNGAYTAYATHACNGCNGTNTGYAARYTNGTNGTNMGNGTNCARGTNAARCARACN AGYYTNTCNMGNAGYAARGAYGAYCCNTTYGTNTCNATGGTNGGNMGNCCNGTNTTYMGN GGNGCNACNGGNTGYGTNGTNAARGTNTCNGAYCCNTCNGAYATHCARGARYTNCCNTGY AAYAAYAARACNTGY------ATHCARGCNTGYAGYCAYAAYGTNTAYGGNTAYYTNGAY ATHMGNACNAAYAARTAYGTNGTNTGYGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AAYAGYYTN YTNYTNTTYYTNGAYCAYAAYTCNMGNACNYTNACNCCNGARAARYTNTTYMGNAARACN ATHTGYYTNCAYCAYCAYGGNTGYCCNGGNCCNGTNTAYAARAAYYTNACNMGNGCNYTN TGGGARYTNTCNMGNATHYTNYTNTTYYTNYTNTTYGTNATGGTNATHGTNATGGCNTTY GGNGAYGCNTAYAARGTNTCNACNACNAAYCARYTNYTNGCNACNGTNGCNGGNGGNTTY YTNCCNTTYYTNTTYMGNTAYYTNTTYACNTCNAGYGARAARGTNAGYACNGTNGAYCCN CAYAGYGTNCARTTYCARGTNGARATHGAYAARGTNATHGARGCNTAYCAYCARTCNTGG CCNGTNTTYGAYATHATHCCNGCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATHACNMGNGGNGAYNNNNNNNNN GCNYTNMGNAGYGCNYTNTTYCARGTNYTNGTNAARGGNGTNMGNGCNACNCARCAYTGG ACNGGNATHATHGGNATHATGGAYAGYYTNCAYGAYYTNTTYAAYAAYCAYTCNGTNGGN YTNCAYMGNTGGACNTTYGCNAAYMGNYTNCCNGGNCAYTGYMGNGAYAARYTNGCNTCN YTNTCNAARTGYGCNYTNTCNYTNTAYGCNACNATHGARGARGTNCAYAAYYTNCCNACN MGNGARCARMGNGARAARMGNACNATHAGYYTNTTYAAYTCNAGYGCNACNTTYGAYMGN GARYTNATGGARGGNATGAARGTNATGATGYTNYTNAGYYTNGTNGARYTNGARAGYMGN ATHMGNGAYYTNGARGARGTNCCNGTNTTYGGNCAYYTNYTNTTYGCNMGNGAYACNTCN GARACNGTNGCNGAYTTYYTNGTNAAYCAYYTNAAYCCNGTNGGNGAYACNGGNGGNYTN GARCARGTNGARATGTGYYTNYTNGGNTAYACNYTNGGNGTNMGNATHMGNGTNTTYMGN YTNTCNCARCAYGGNCARCARGAYTTYGAYTGYTTYTTYCCNGARGAYATHGCNCARGAY TGYCARAAYATHGARYTNYTNGCNGARGAYGAYMGNCAYTAYAAYGTNCCNYTNCCN--- ---------------------------TTYTTYGGNYTNCCNAAYGGNATHGCNGTNATG GAYGCNYTNACNCARACNGARATHAAYAARTGGGAYGARGARAAYGTNGARATHATHAGY ATHCAYTCNTGYYTNTTYCARCCNAAYCARCAYTTYATHGCNACNGTNGAYATHATGGGN ATHGCNMGNGTNTTYYTNTTYGCNTTYAGYCAYATHTTYTTYATHAARACNATGAAYGAR AAYGCNGTNGARAGYACNTCNAARGTNATHTGYCARAARTGYCARGCNTCNCARGARGCN GAYTAYATGGGNGTNGTNTTYGARAAYACNAGYAGYAARGARGTNTGGYTNGARGTNCAY AARAAYCCNGTNGARGCNTGGGCNAARGARYTNGARGGNATHGGNAGYATGYTNACNAAR CARAARGARGARGCNGARAARGCNCCNGTNGARGTNACNGAR------ACNATHCARGAR GARAARGAYACNCCNGCNGCNGARATGCCNGTNACNGAYCARCARAARGAYCCNCARGAR GARAGYTCNATGATHGARAARYTNGGNACNAARTTYTCNCARCCNACNYTNGTNYTNAAR GTNAARAGYCCNCARGTNTAYCCNYTNCCNGCNAAYAGYTCNTCNAGYATHGCNTCNGCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------MGNTCNYTNCARCAYGARYTNGTNAAYGTNCARTCNCARGTNMGN ACNATHGGNACNGARYTNGARAARGCNAAYMGNACNGAYCCNGGNTAYATHGAYYTNGTN AARAARGARCAYGARGTNYTNYTNATHGARAARGAYATGGCNAARCARATHCARACNYTN GAYAARAGYGARMGNNNNTTYTTYTCNTAYYTNAGYACNGCNGTNMGNGARAGYCAYGAR AARGARMGNGCNMGNGCNGARMGNACNAARTAYTGGTCNATHATHGGNTCNGTNGTNGGN GCNGCNYTNGGNATHATHGGNTCNACNTTYAAYAAYCAYMGNMGNYTNAARGARATGMGN GCNATHGTNACNGARTCNGARGGNAAYGTNACNGARTAYAARGARYTNACNAAYAARYTN YTN---------------------YTNACNATHMGNTTYATHAGYGAYGAYGARATGGAR TCNACNACNMGNGGNTTYAARYTNYTNATHYTNTAYGCNACNAGYACNCARGARYTNGAR AARAARGTNTTYYTNGCNMGNAARMGNAGYGGNAARTCNGAYAARGAYTCNYTNAAYTGG ACNYTNGTNATHATHGTNGCNTTYAGYATHYTNGTNATHATHATHATHGTNGTNGTNGCN ACNATHGCNATHTCNMGNCARTGGMGN------------------------------YTN CAYAARGTNGGNYTNGARTCNAGYTCNACNGGNTCNTCNTTYCCNGCNGAYTCNGCNAAR CCNGTNCCNYTNGCNGTNGTNTCNYTNGAYAGYMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGNGCNGAYGARGAYGARAAYGARGAYGAYGAYGARGAYGAYGAYTTY TAYAAYGARCCNCCNCCNGARTTYCCNTCNGCNACNAARTGGGAYACNCCNGCNCCNACN ATHGGNGGNAARGGNTAYTCNGGNCARGGNAARAAYATHGTNACNAARCAYGAYAARGTN ATHTGYGGNMGNMGNAAYGCNGARMGNYTNATGGARYTNCCNCCNGGNGTNGAYATHGGN GAYGGNGARGGNATGGAYATGCARYTNCCNAAYAGYGTNTAYAAYTCNYTNAARACNCAY TCNYTNGGNGARAAYAARAARAGYATGAARATHCAYGARAARAARGAYCAYTCNACNGCN ATHAARGCNGTNGAYGARAAYACNMGNATHYTNYTNTTYAARATGATHAAYAAYGGNTCN YTNTCNTCNATHGAYGGNGTNGTNAGYGARGGNAARGARGCNATGATHTTYAARGCNACN GGNGGNGTNAARGGNGARGTNGARYTNCCNCARCAYGTNATHYTNAARATHTAYAARACN ACNATGAAYGARTTYAARACNMGNGCNMGNTAYGTNTAYGGNGAYCAYCARYTNTCNAAR GAYYTNTTYAARAARCARAAYCCNMGNAARGTNATHMGNATHTGGGCNGARAARGARTTY YTNAAYYTNAARMGNATGYTNMGNMGNGGNATHCCNTGYCCNCARGCNATHTAYYTNAAR AARAAYATHYTNGCNATGAGYTGYATHGGNGGNGAYCAYCCNGCNCCNAARYTNAARGAR GTNAARTTYAGYACNGARGAYYTNCARGAYGCNTAYGARCARACNATHGAYYTNATGAAR MGNATGTAYMGNGAYTGYTGYYTNATHCAYGCNGAYYTNAGYGARTTYAAYYTNYTNTGG CAYGARGARAARGTNTGGGTNATHGAYGTNAGYCARTCNGTNGARCARCARAAYAARAAY TCNGGNGAYTTYYTNYTNMGNGAYTGYCARAAYATHTGYMGNTTYTTYAARCARTCNGGN GCNCAYGGNGTNGCNYTNCCNGARGARYTNTAYMGNGAYATHACNAAYTGYGAYYTNGAR GGNGARGGNAARGTNTTYGCNTCNCARATGAARAARTAYGARAARGAYGAYTAYGCNTTY GAYTTYTTYTTYGARAAYCARAARAARGCN---------------TCNTCNGAYGAYGAY GARGAYGAYGAYGAYGAYGCNGAY---------------------GARMGNGCNMGNTCN CARAAYATGMGNYTNCARGARGARATHGAYMGNMGNTAYAGYMGNCCNGAYTCNAGYACN AAYAAYYTNYTNTAYGARGTNATGACNYTNMGNACNAARGARTTYGARAARTCNCARGCN AARAARGCNGCNACNATHCARAAYYTNACNYTNGARMGNCARMGNATHATGGAYGCNMGN ACNCARCARGAYMGNGAYCAYCAYAARMGNGGNGTNTGGGCNCAYTCNCARCARATGGTN CAYCCNGCNGTNCCNCCNCCNGARCCNYTNYTNMGNGGNGGNYTNCCNCCNCCNCCNCCN GTNAARGGNAARAARAARGGNCCNCARCARACNCARCCNGCNAARCCNGARGCNCCNAAR CCNGARGARCCNYTNGARCCNGAYGTNATHYTNATHATGCAYGAYCAYYTNAGYCCNACN AAYYTNAARGTNAARCARTGGYTNAARGTNGAYGAYGCNGARGARAARTTYCARAARTTY TGGTCNGAYGTNTAYCARACNAARGARGTNGCNTAYTGGGGNAARTTYMGNCCNTTYATG TTYAAYGTNCCNYTNGCNAARMGNTGYGARGGNGTNCAYATHYTNMGNCCNTCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNGTNACNGARCARCARGTN GGNYTNTCNGARTAYYTN---GGNGGNCAYTCNGGNTTYTGYGCNGTNATHAARCARMGN TAYTCNGAYTTYATHGTNAAYGARATHGAYCARGARGGNAAYACNGTNCAYYTNACNGAY GAYGARGARAARGAYGAYAGYAAYGARACNGARGCNAGYGARCARGGNGARAGYACNGAR AGY---GTNYTNAGYGARGAYGAYGARAAYAARATGAARGARYTNGCNGARAAYGTNGAY AARGTNGGNGARYTNAAYATHYTNGCNCCNGAYGAYAARGAYYTNMGNACNAARATHCAY YTNACNGTNAARAARMGNTTYAARCARTTYGARACNAARACNACNGARGAYGAYCARGGN MGNAARGTNATHCARGTNTTYTGGMGNAARGGNAARGCNAARGAYTTYMGNMGNGAYGAR TGGCCNAARACNAARAARTCNTGYMGNTAYGTNMGNTTYGTNYTNTAYAARGARAAYAAR GAYACNATGGAYGCNATHGGNYTNATHGCNAARAAYYTNAARGTNAARGARAGYATGTTY CARTAYGCNGGNACNAARGAYAARMGNGGNAARACNTCNCARGARGTNACNGCNCAYMGN ATHCAYCCNAARAARYTNTCNTGYYTNAAYAARGTNYTNTGGAAYATGGGNYTNGGNAAY TTYMGNTAYGTNCARGARCCNATGAARYTNGGNCARYTNAARGGNAAYCAYTTYATHATH GTNYTNMGNAAYGTNCARGGNGARAARGARAAYATHGARGAYGCNYTNATGTCNYTNAAR TCNAARGGNTTYATHAAYTAYTAYGGNATGCARMGNTTYGGNACNAGYTCNATHCCNACN TAYAGYGTNGGNMGNGCNYTNYTNCAYGARGARTGGGAYAARGCNGTNAAYYTNATHYTN ATGCCNMGNGARGAYAARGCNTCNAARGTNGARTTYCARAARGTNTGGGARGARACNCAY GAYGCNTCNGCNACNYTNAARGTNATHCCNMGNTAYTGYGGNYTNGARMGNAAYYTNYTN CARGCNYTNAGYMGNAAYYTNAARCCNATGGARGCNYTNGARMGNATHTCNMGNAAYACN MGNYTNATGTAYGTNCAYAGYTAYCARTCNYTNATHTGGAAYCAYATGGTNTCNAARMGN YTNAARGARYTNGGNACNAARCCNGTNGTNGGNGAYYTNGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ACNGAYGARGTNTGYGARGTNATHTCNAAYACNYTNGGNGARTAY YTNAARTCNGARGAYMGNACNAARYTNCARTAYGTNACNGARATHTGYAARGTNGAYCCN GARAAYGTNCARACNATHGAYGARGARGARMGNGGNGAYATHAARATHACNGTNAARYTN ATHATHTGYGCNTCNCARACNCCNAGYGTNATHAGYGAYGCNYTNAAYMGNGTNYTNGGN GARYTNAAYACNCCNTTYGTNGARACNYTNYTNYTNGCNTTYAGYATGTCNTCNGAYGAR GTNGARGARYTNCARGAYGGNYTNACNYTNAARGTNATHCARCCNTAYTGGCARGTNATG GARGAYYTNAARGARAAYGAYAARGTNYTNTCNYTNGGNGTNTGYGAYYTNAAYAARGAY TCNYTNGARGARYTNTAYAAYTGGGCNAARGTNAARCCNTGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CARGGNYTNATHYTNGARAGYTTYTTYAGYACNGAYACNGAYCAYGGNCCNGCNMGN TTYYTNATHTTYTCNYTNYTNATHCCNTTYATHCAYMGNGARGGNCCNGTNGGNCARAAR GCNMGNGAYGCNYTNYTNYTNATHATGACNYTNTCNGCNMGNCAYCCNCAYATHGGNCAR TAYATHGCNAAYAAYTCNCAYTTYTGYCCNGTNYTNGCNACNGGNYTNAGYGGNYTNTAY TCNTCNYTNCCNMGNMGNYTNMGNCCNCCNTCNGARGAYTGGGTNGCNATHACNCARGAR GAYTGYGTNMGNATHCCNGAYYTNCARATGTCNYTNAAYTCNYTNCARTTYTCNAAYGCN GTNGTNCAR--------------------------------------------------- ------------AAYGGNGGNGAYTCNGCNTCNGAYMGNAARMGNAARMGNMGNAGYMGN TGGAAYACNGARAAYAGYGARAARACNGTNATHCCNGGNATGCCNACNGTNATHCCNTCN AAYYTNTCNGAYTCNCARCARMGNCARTAYGTNGTNCAYYTNCARATHGARGARATHAGY MGNAARYTNMGNACNGGNGARYTNGGNATHCCNTCNAAYCCNGARCARMGNTCNCCNTCN CCNGARCCNATHTAYAAYAAYGARGGNAARMGNYTNAAYACNMGNGARTAYMGNACNMGN AARAARYTNGARGARGAYMGNCAYAARYTNATHCARGARGCNYTNAARYTNAAYCCNGAR TTYAARCCNCCNAGYGAYTAYAARCCNCCNGTNGTNMGNGTNAGYGAYAARGTNATGATH CCNCARGARGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYYTNACNGGNATHGARATGGTNCARGCNGCNGARACNGCN GARYTN---GCNGCNGCNGCNGAYAGYATG---GCNATHYTNATGCCNCARCCNTCNTCN AGYCCNGARYTNCCNAGYGGNTGYCCNCARTGGGCNATGMGNYTNMGNAARTGYGARAAR ATHGGNGAYTCNTAYMGNGGNTAYGTNGARAAYGARGTNGAYYTNGARTTYATHYTNACN CARCAYAARCARCARACNAAYAGYTTYTGGGGNACNMGNCARTCNCCNAGYACNGCNAAR ACNTCNACNMGNYTNATGTGGAARTCNCARTAYGTNCCNTTYGAYGGNATHCCNTTYATH AAYGCNGGNAGYMGNGCNGTNGTNATGGARTGYCARTTYGGNCCNMGNMGNAARGGNAGY GGNMGNMGNAAYAGYTGYGTNGCNAGYAAYGGNTTYMGNCARACN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GTNATHGAYAGY MGNTCNTTYYTNGARTTYAAYACNGGNAAYATHCARCARTCNGTNAAYATGTGYTGYTCN AARYTNGTNAARMGNMGNYTNCARCARGAYAARGTNCARGTNYTNGAYYTNYTNAGYCAR ACNTGYCAYATHGGNGCNGAYGCNTCNTGGGAYGTNATHGTNTAYGAYCARTGYACNGAR GAYCCNTCNYTNYTNMGNAARYTNAGYACNGCNTTYAAYAGYGTNGCNTTYYTNAARGGN GGNTTYYTNGCNTTYCARGCNTCNCAYTCNAGYYTNGTNGARAAYAARTCNAGYAGYTGY TCNACNYTNACNTCNYTNTCNCARCCNTGYATGCCNGTNAGYAAYGTNGGNCCNACNMGN ATHYTNCCNTTYYTNTAYYTNGGNAGYCARCARGAYGCNATGGCNCCNGAYATHGCNCAR GTNAAYGGNATHAGYTAYGTNYTNAAYGTNAGYAARAAYTGYCCNMGNCCNGCNTTYATH CARGARGGNCAYTTYCAYMGNATHCCNGTNCAYGAYAGYTAYTGYGCNAARYTNYTNCCN TTYTTYCARGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AARTTYAAYGTNGCNTTYYTNAARACNCAYAARGCN GGNAGYTCNACNGTNGCNAAYATHYTNCARMGNTTYGGNATGMGNMGNAARYTNAAYTTY GTNYTNCCNMGNAARAARMGNAGYGCNMGNGGNGTNAAYTAYATHGTNAARGGNAAYCAR ACNTTYACNCCNGAYMGNYTNTTYCCNCCNCCNCCNGGN---GARAGYTAYAAYATHYTN TGGTGYCAYAGYGTNTAYAAYMGNACNGCNTTYMGNGCNGTNATGCCNGARGAYACNGTN TAYGTNACNGTNYTNMGNCARCCNTTYCARCARTTYGTNTCNTAYTTYGARTAYTAYCAY TTYGGNAARCAYTGYGCNGAYMGNGAYGCNGCNATHYTNCARTCNCAYAAYCCNATHGCN TAYTTYYTNTCNGAYGARYTNGTNCARTCNYTNGGNCAYYTNGTNYTNAGY--------- ---ACNCARATHTTYGAYYTNGGNTTYAARCCNMGNMGNCAYTAYGGNGARGCNCARYTN CARGAYTAYATHMGNYTNYTNGAYGGNGAYTTYCAYYTNGTNATGATHYTNGARTTYTTY GAYGARTCNYTNYTNYTNYTNAARMGNAARYTNTGYTGGTCNATGGARGAYATHYTNTAY GTNCARYTNAAYGCNAAYMGNTGGAARGARMGNAGYACNGTNCARMGNMGNCAYMGN--- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNYTNTGGATHTGYAARAARTGYGARTCNCARGARMGN GTNGCNMGNGTNAARTGYGARYTNTGYCCNCARMGNGAYGGNGCNYTNAARMGNACNAAY TCNGGNGGNTGGTGYCAYGTNGTNTGYGCNYTNTAYATHCCNGARGCNTGGTTYGCNAAY GTNCARACNATGGARCCNATHGTNYTNACNTCNGTNCCNCAYGARMGNTTYAAYAARACN TGYTAYATHTGYGARGARCARAARMGNGAYACNAARGCNACNGCNGGNGCNTGYATGCAR TGYAAYMGNAGYGGNTGYAARCARTAYTTYCAYGTNACNTGYGCNCARGCNCARGGNYTN YTNTGYGARGTNATHGGNAGYTAYGARAAYGTNAARTAYTGYGGNTAYTGYACNCAYCAY TAYAARAARYTNAARAAYYTNTCNAAYGTNAARACNATHCCNGCNTTYMGNCCNATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYGAYGCNCCNYTNGGNCAYACNTGYACNYTNACNCCNGAYATHGTN MGNGARGARGTNGAYACNYTNAARMGNGAYTTYAAYATGMGNYTNAARCARATHYTNTTY AAYTCNYTNACNACNTCNTTYTAYGCNACNGGNGTNCCNGTNTGGTTYTCNCAR---AAY ACNYTNTAYTAYGAYTCNTGGTGGATGTGGCARCAYGTNTGYYTNACNTGGYTNAGYTCN YTNYTNATGYTNACNTCNCAYTTYYTNCCNCCNCAYTAYYTNCAYYTNYTNCAYAARAGY GCNMGNCAYYTNGGNMGNTGGCARMGNATGGARGCNMGNCAYGCNCAYGTNCCNTAYAAY GCNTGGTCNGARYTNCARGTNTGGCCNCARGGNGCNYTNGTNAARCAYGTNAARGGNYTN TTYAARGCNGARGGNYTNACNGTNACNGCNGARCCNGGNAAYACNYTNCAYAGYMGNTTY TAYYTNYTNTTYCAYCAYCCNATGMGNGTNATGAAYTGGYTNGTNTTYYTNTCNTGYATG GTNGTNGGNTAYCARTTYTTYMGNYTNGTNCARAGYTCNGARTGGAGYCAYGTNATHTCN YTNGCNYTNYTNATGTTYTGYAAYTTYTAYACNYTNTTYAARYTNATGMGNGAYTGGTTY ATHATGGGNAARGTNTAYAARGARMGNGAYTAYGGNYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GGNMGNACNAARTAYACNTAYGARGARGAYYTNAARATHATHAARTAYYTNATH TCNTAYMGNAARATHGGNGGNAAYGTNYTNTGGAARMGNATGGARTCNYTNCARGTNACN AARCAYACNAGYCARAGYATGAARGCNMGNTAYAAYMGNGTNATHYTNCCNAGYATHMGN ACNTAYGAYGTNCCNGCNATHTGGAARGAYMGNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CCNGCN TTYCARTCNGTNCCNTAYATGACNTGYCCNGGNGTNGCNGARGARGARGGNGGNMGNTAY GCNCARTAYATGCAYMGNTTYTCNATGCCNGARACNAAYTGGCCNATGTCNYTNGAYAAR YTNTGGTAYAGYGTNGAYATHGGNACNGTNCAYYTNATHAGYYTNTCNTCNGARGTNTTY ACNAAYAGYGGNGAYTTYGCNGCNYTNCARMGNAARTGGYTNATHAARGAYYTNMGNMGN GCNAAYGAYCARMGNAARGARGTNCCNTGGGTNATHGTNTTYTCNCAYCARCCNYTNTAY TGYAGYAAYCCNGAYCCNGGNYTNACNTGYAGYGAYAARAARTCNAARATHMGNYTNGGN YTNGARGAYGTNATHTAYTCNTTYGGNGTNGAYYTNGTNYTNTCNACNTAYGAYGGNGCN TAYGARMGNTCNCAYCCNATGTAYAARGGNTAYGCNYTNGCNGARAAYTAYACNAAYCCN GTNGGNCCNGTNTAYGTNAAYYTNGGNGCNACNAGYCCNTGGCARGCNTCNTAYAAYTTY ------TCNGAYCCNGAYTGGYTNGCNATGMGNGTNGAYCCNCARGARGARGGNAGYTTY GGNMGNATHAAYGTNGTNAAYGGNTCNMGNYTNGARTTYCARCARATHCARYTNCCNCAR TCNCARACNYTNGAYAGYTTYGTNATHNNNCARGAYAAYCAYGGNCCNTTYTCNACNCAR TCNYTNCCNGAYGAYYTNACNAAYAARATHAAYGAYGARATHATHGARTCNGGNGGNAAR CCNGAYCARATHAAYCCNTCNGAYGCNGAYGCNAGYGAYGTNACNACNAARATHAARCAR TTYYTNAAYGAYGAYAAYAARAAYAARGTNATHATHGGNATHTCNTGYTTYGCNGGNGTN GTNGTNTTYATHGTNGCNGCNTTYGTNGTNMGNMGNATHACN---MGNMGNMGNMGNATH GCNTCNMGNMGNTGGGARACNATGGAYATHAAYTAYGGNAARMGNTAYTAYAGYAARGCN CCNGAYMGNGAYGAYACNGAYAAYGAYTTYGARATHGAYATHGCNGAYACNACNGAYAAY AARAARYTNYTNACNGAYGAY---------------------------YTNCCNGAYTTY YTNGCNGAYGGNCCNYTNYTNAAYGCNAAYCAYGGNTCN------------AARYTNGAR TCNATHGAYACNGGNACNYTNCAYGARGAYYTNYTNACNMGNGTNMGNGARYTNCARGAY GARAAYCAYAAYYTNMGNTCNGARYTNGCNMGNGARAARCARAARTGYAGYGARAARAAY AARMGNYTNACNCARATHAARCAYGAYYTNGARMGNCARAARAARAARGARGCNGARGAR ACNGCNGTNATGGARAARGCNATHGARCARGTNGARGARAAYYTNGTNACNACNACNAAR MGNGCNGTNGARGCNGARTCNGTNGTNACNAAYYTNAARCARGARGTNAARAGYYTNCAR GCNCARGTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNTTYCARAGYTGGACN ATHCCNAAYMGNATGGTNCCNGARCARGTNCCNACNGCNMGNGARAAYGCNGCNYTNGCN TCNACNYTNGTNGGNMGNMGNGARAARCCNGAYATGTCNCCNGCNYTNAARMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNGARAAR ATHGARCCNGAYTCNCARTCNTAYTTYACNGTNGAYAGYTTYGAYCAYCCNCAYGTNYTN GAYTTYTAYGAYMGNYTNYTNTTYACNYTNTGGGTNCCNCAYAAYATGACNGARATHAAY YTNAAYCCNGAYAARCCNAGYAARAARCARYTNGARGGNAAYCARGARYTNTAYGARCCN GAYTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNGTNYTNACNGGNCARACNAGYGAYAAY ATHTCNTCNYTNGTNATGCAYGARGTNMGNGARATHGARACNTGGATHYTNMGNYTNYTN AGYGCNCCNGTNCCNGTNCCNGGNAARACNMGNGTNGARGTNCARGTNYTNCCNMGNGAR YTNCARCCNCCNYTNGTNTTYGCNYTNCCNGAYAAYACNMGNTTYAGYYTNGTNGAYTTY CCNYTNCAYYTNCCNYTNGARYTNYTNGGNGTNGARACNTGYYTNAARGCNATHACNGCN ATHATGYTNGARCAYAARGTNATHATHCARTCNMGNGAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGNGTNTTYATHCCNAARGCNCAYMGNYTNTAYTAYAAR GTNGCNGARTTYCAYGARGAYTTYMGNTTYAGYYTNAGYTTYATHGARAAYTGYGTNGAR ACNCCNATHTCNAARGCNYTNTGYGARAARGCNTGGYTNTTYMGNGGNAARATHTCNMGN AARAAYAGYATGATGMGNYTNAGYACNAARGAYATGGARAAYTGYATHTCNACNATGATH AGYYTNGTNTCNGTNAARAGYATHGGNGGNAARGCNGARGTNATHGARAARYTNAARGTN YTNATGAAYGAYAGYGAYGTNTCNGARTCNGGNTGYTGYGTNATG--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CAYAARGCNAARTCNAARGTNYTNGARTCNGGNGCNGARAAR GAYAGYYTNGARGTNYTNGARAARGARGAYAAYGTNYTNGCNTAYATHCCNGGNGAYGTN ATHGARATHAARGTNAARGTNGTNGGNAAYYTNAARATGTTYGARACNGARAARGGNCAR ATH---AGYACNTGGCARTCNCAYGAYTGYTAYCARGAYGTNYTNACNMGNGAYTGYAAR GARGCNGARAARCARACNTTYTCNGTNACNGGNGCNAARATHGAY---------GARGAR GCNACNGARGAYCCNMGNAARCAYCCNCARGARCCNACNGTNGAYCCNGAYACNGGNGAR TGGATHYTNTCNCCNTGGGAYATHGARTGYATHGTNGTNGGNGCNGGNATHTAYGGNTGY GGNGGNGGNGCNAGYCCNCAYATGGGNMGNYTNMGNACNCARMGNYTNYTNAARGARGGN AARAARYTNMGNGTNATHAGYGCNGARMGNYTNATGTCNAGYCCNGGNTCNGARAAYAAY ATHGTNGTNGTNTCNGCNTTYATHGGNGCNCCNYTNTGYATGTAYGARCARGGNGTNTCN TCNAARGARACNACNACNGCNYTNCAYTGYYTNAARGAYYTNTAYGARATHGGNAAYTAY MGNGAYGGNGAYATHGCNAAYAARGTNGGNGTNMGNATHGAYACNAARGAYTCNAARATH MGNTAYATHCAYAAYTAYCCNCCNGTNGARGARACNGCNACNTCNGAYGCNTCNATHGTN GCNGTNATGTCNGCNGARATHGGNGGNATGAAYGCNATGGARCCNTTYYTNGTNGCNGGN AAYATGGAYYTNCCNGTNGTNGAYGGNGAYGGNATGAGYMGNGCNTTYCCNGARGTNCAR ATGTTYGTNCCNTAYATGTAYGGNTCNCCNCCNTAYCCNGTNGCNATHGTNGGNTCNGGN AAYACNACNGAYNNNAGYGTNGTNYTNTAYTCNCCNAARAAYATGYTNYTNGARAAYTTY YTNMGNGAYGTNTCNATHGCNCAYGGNTGYTCNGCNGGNATGGCNYTNTCNGTNACNAAR GAYGAYYTNTTYAAYAARACNTGYYTNAARTCNGTNAGYAGYGCNTGGMGNYTNGGNGAY GCNATHYTNMGNGCNMGNYTNAAYAARGARTCNGTNATHGAYGCNATHYTNAAYCARGAR GAYGCNAARCAYGTNATGACNGGNAARATHACNGAYGTNCARMGNGARACNAGYGGNGGN TTYAAYMGNGGNCAYYTNGTNYTNGARGGNATHGARGAYTGGGTNGAYMGNGTNYTNYTN GTNGARTTYCARAAYGARAAYYTNGTNATHGTNCCNYTNGARGAYGGNCARMGNGGNYTN TGYYTNGCNTCNACNCCNGAYYTNATHTGYATHGTNGAYGCNGAYTCNGGNGARCCNGTN CCNGTNGARGARGTNMGNTAYGGNATHMGNGTNGCNYTNATHGTNATGCCNTCNTTYGAR YTNYTNMGNMGNCCNGARGCNYTNAARTGGGTNGGNCCNAARGCNTTYAAYTAYTCNGAR GAY------TTYAARCCNTAYAARCARMGNAARGARACNGTNCCNATHCCNCCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYMGNYTNGCNACNYTNAARGCNGGNGTNTTYTTYGGN TGYATHACNTTYATGTCNYTNYTNTCNGGNTTYGGNATGACNYTNGGNATGACNAARAAR CARGAYCCNAAYAGYTTYGCNAARGGNYTNGCNGGNGGNGCNGARATHCCNGARAGYGGN ATHAGYYTNGCNTCNMGNGCNYTNGCNMGNGGNTCNYTNTAYGCNGTNGGNGGNTTYAGY YTNGTNTGYTTYACNGTNTGGAARYTNGTNGGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARGARAARAAYGTNCAYTAYGCNCARMGNTGYGCNAGYYTNAAR YTNGTNGTNYTNGAYYTNCARCARAARYTNACNGTNTAYAARAAYMGNTGYGTNGGNATG GAYTCNYTNTCNYTNATGYTNAARGARGCNAARCARGARGTNGTNAARYTNAARAARCAY TCNAARGCNYTNGARACNGCNYTNACNAAYYTNCARAAYMGNYTNGCNGCNCAYGGNYTN TCNAGYAGYGTNAGYATHCARGARACNGARYTNTAYATHCCNGGNGCNTCNTTYCARACN YTNGAYAAYYTNGCNAARGARAAYGCNMGNYTNMGNAAYYTNYTNAARAAYGGNGARGGN CAYCARACNGARAARATHCCNAAYGAR---------GAYAAYGCNCAYYTNGARGAYYTN GARGCNGARAAYAAYCARYTNAARGCNCARYTNYTNGAYYTNCARGGNATHAARATGGAY TAYGTNGCNAARTTYAAYAARGARATH------------GARAARAARGARYTNAARGAR GARAAYYTNMGNGTNGARYTNMGNCAR---------YTNGARGARAARATGAARAARYTN GARGCNGTNAARGGNGTNATHAARGAYGTNAGYGARCARMGNCARCCNGAYACNGARGCN GGNCARATHGCNAAYATGGARAARGTNGAYGARYTNMGNAARTGYAGYTCNYTNGAYAAR AARYTNCCNATHATGCARGARCARGARTCNAAYYTNCARACNAAYYTNGARGARGTNATH YTNATHAAYAARMGNTGGAARGARCAYTCNACNAAYCARGARCARMGNATHCAYACNYTN ACNGCNMGNGTNCARGARYTNGAYAAYCCNGARCAYTTYCARATGCARYTNAARGAYTCN GCNGARGCNCAYAARAARGARTTYGCNMGNYTNMGNGGNGARATHGARGTNMGNAAYAAY GARATHAARGARCARAARAAYTGYATHYTNATHYTNACNCARCARYTNCARAGYCARAAR TCNCARCCNCARGCNCCNCARGTNGAYATGAGYATHGTNGARATHYTNAARCARCARATH CARGTNTGYACNGARGAYTTYGAYACNGARMGNAARGAYMGNGARCARGCNGTNAGYAAR GTNAARGARYTNCARGCNGARGTNATHMGNYTNAARAARGARAAYGAYATGTTYAARAAR GARATHACNATHATGMGNGARCAR------------TAYATHATHTGYTTYATHTCNTTY CARGARAGYACNYTNGARYTNTTY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CCNTAY------------TCNGTN GAY------AAYTCNAAYGARTGYAAYGAYGAYAAYTAYTGYGTNAARTAYAARACNTTY ATHTGGATHMGNGAYTCNGGNTAYATHACNGGNAARGARMGNGTNTCNTCNACNGTNACN MGNACNTGYCARCCNAARGGNGGNATGAGYCCNGGNTGYAARGCNTGGCARGGNAAYGGN GGNTAYACNATHAARTGYYTNTGYGAYACNGAYTAYTGYAAYGCNGGNAGYATHTCNYTN CCN--------------------------------------------------------- ------------------------------------------------------------ ---------------------------MGNTAYMGNMGNGARGCNGARGARMGNGTNGTN GARYTNCARTCNYTNGARAARGCNAARGAYGARTTYCARGARMGNTGYGARAGYGCNAAR MGNGARYTNAAYAAYMGNGTNMGNTCNGTNAAYCARCARTTYACNATGYTNCARAGYCAR CAYMGNGARACNGARGCNGAYYTNGARAARYTNAARCARGAYATHGAYGTNATGMGNAAY GARMGNYTNCARGCNGARAAYTCNCAYGCNCARGARTTYCARGGNYTNAARGAYCARAAR ACNGCNGARATHGARAARYTNACNGGNGARYTNCARTCNYTNTCNAARAARAAYGARGAY GTNCARAGYYTNGTNACNAAYYTNCARTTYCARYTNCARAGYYTNGAYGARGCNCARCAR AARYTNYTNYTNCCNTCNAAYCARCARCARAAYCARGTNCARAGYAAYCARCARGCNGTN CARCARAAYCARCARCARCCNTCNCAYCARAAYCARCARCARGARCARCARCARAAYTTY AAYAAYAAYAAYTAYCCNACNTGGYTNACNYTNATHCCNTCNTCNTTYYTNYTNGGNGCN ATHGCNGCNCCNATGTGGACNTCNCARGGNYTNTAYATHACNTCNGCNAGYGARGARTAY GCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARGARAGYAARTCNGCNGGNAARAARGTNATHCCNCCNYTNATGYTNGAYTCN YTNGGNMGNCCNATGTTYCCNATGGTNYTNGGNGAYGTNACNYTNCAYAGYATHGGNGAR ATHGTNCCNGARMGNYTNAGYTTYCAYTGYCCNGARGCNATHTAYCCNGCNGGNTAYTGY ATHACNMGNGTNTAYGCNAGYYTNCAYAARYTNGAYTCNAARTGYYTNTAYACNTGYAAR ATHTCNGAYAAYGAYGAYGGNCCNYTNTTYGARATHGCNTCNGARGAYAGYACNGAYATH GTNTTYAARGCNAAYGAYCCNTCNGARTGYCAYAGYYTNYTNYTNMGNGCNGTNAAYAAR TCNMGNGGNACNGAYACNYTNCCNATHGARMGNMGNGGNYTNGAYTTYTTYGGNYTNTCN CAYCCNGTNGTNCARAAYYTNATHCARTCNTGYCCNGGNGCNMGNAARTGYTCNMGNTAY AARTGGGTNAARTTYGARATHAAYAARTCNGARGTNAAYGARAAYGTNGCNGTNGGNAAR AAYGAYCCNTGYGTNAGYTTYGAYGCNTTYMGNGTNYTNATHCARTCNTTYGCNCARAAR CAY------CARGCNTCNGCNGGNGGNGAYCARTCNACNAAYYTNMGNTCNYTNYTNACN AARGGNAGYGGNATGAARTTYTCNGTNGARGARATHGTNGCNACNGGNGGNMGNATHGGN MGNATH---GTNACNGGNCARAAYGGNAGYCARACNYTNGARACNCCNYTNTGYTAYYTN TTYACNAARGGNGGNTCNGCNCCNCAYYTNAGYYTNGAYATGYTNAARAARGTNAARTCN GTNCCNATHYTNACNGCNATGAAYATHGGNACNTTYGCNGAYCAYGTNGARAAYGTNAAY GARTCNGGNCARACNYTNGGNGARTTYACNTCNATGAARTCNCARYTNATHTTYACNACN ATGCARGAYGCNAGYCARGCNYTNAARTCNGGNAARAAYACNAARTCNGAYATHGCNGTN TGGGGNAARGGNGGNAARGTNAARYTNGAYCCNGCNYTNTAYTTYMGNYTNCARGARGTN TTYCARCCNGAYTGGTTYCARGCNYTNAGYGAYGGNGAYACNGAYAARGAYAGYACNGCN AARMGNYTNGGNAARTCNGTNGAYMGNACNYTNGAYTTYYTNGAYGARATHYTNCARYTN CARCARAARAGYGARCAYYTNAARAGYGCNAGYYTNATHGGNGTNATHGARGGNGGNTTY AGYGARCARCAYMGNCARAARTCNGCNAARGARACNGCNTCNMGNCCNGTNAGYGGNTTY YTNATHGARGGNTTYCARAARGGNTGYACNGAYGARGAYGTNTTYGAYCAYAARGAYTTY ATHAGYGTNYTNTCNAARACNATHAGYCAYYTNCCNGGNGAYAARYTNMGNATHATGGAR ACNCCNTGGTCNCCNATHCARGTNATHAARGCNTTYAARYTNGGNATHGAYGTNTTYTCN AGYGCNTAYCCNCAYACNYTNACNGARAARGGNCARGCNYTNGCNTAYGAYTAYTGYYTN CCNCCNMGNTCNCARGCNGCNMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GCNTTYTTYTCNTAYACNATHGAYGAYTTYMGNMGNTGGMGN TTYMGNAAYGCNACNATHGTNGTNTGGYTNYTNTGYAAYGTNGCNTGYGTNTGGYTNTCN CARGCNGCNGTNTTYATHGTNGTNTCNGCNYTNGTNATHGGNGTNGCNACNYTNAGYYTN TTYCARATHCAYACNMGNYTNYTNGAYAARATHTTYCCNAAYCCNAARMGNGTNGTNGGN GAYGTNAAYTCNAAYCARATHAGYGARGCNYTNGGNACNGTNCARAAYTTYMGNTAYAGY YTNATHGARATGCAYGAYTTYGTNGTNAARAGYAAYGARTAYYTNGGNTAYTTYTAYTCN ATHYTNAARTGGGAYGCNACNYTNCCNTCNYTNATHTAYCAYACNGARATHTGYATHTTY YTNYTNAGYYTNGTNGTNTGYCCNGCNMGNTGGAAYTGYTTYYTNTTYATHAAYTGGTTY TTYYTNTGYCAYCCNCAYGTNYTNAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNAARTGYTGYGTNYTNTTYYTNGCNATHGGN GGNYTNGTNGTNGCNYTNTTYCCNYTNGTNATGCARGCNACNYTNYTNTTYGGNTAYGGN ATGTCNACNGTNTGYAGYTGGYTNAGYTTYYTNTGYATGMGNGARACNCAYAARAARAAR GCNATHCAYCAYMGNATHCAYCCNAAYAARYTNGCNTAYGAYGCNATHGTNGTNTGGAAR GGNAARGARAAYCARAARGCNAARCARGGNGGNATHAGYTTYGAYGTNATHYTNAARCCN GCNGCNACNGAYAGYCCNAARACNCCNAAR---YTNGTNCCNYTNMGNGARAARCARAAR GAYYTNTCNCARGARCARATHAAYYTNAARYTNGARAARGCNGARCAYMGNMGNAGYYTN ATHGARAARGARMGNYTNGAYCARYTNGCNAARGARMGNCARAARGCNATHGARGTNATG AAYAARGCNCARACNGARAGYGARCARTTYTCNAARAARACNGARGARAARYTNMGNMGN TCNATGGARGTNMGNMGNGARAAYMGNGARACNCARATHMGNGCNYTNCARGARMGNYTN MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------GARCAYGCNAAYCAYATHAAYGAR GTNTGYATHGCNAGYGARAAYMGNGGNCCNTCNACNGAYGARYTNCARGARCARYTNGTN CAYAARATGGARAAYGCNYTNAARAAYMGNGARGARCARYTNMGNGGNYTNCARCAYMGN YTNTCNGARCAYGARGAYMGNATHAARGARGTNCARAARAARAAR---ATGGARTCNTTY AGYGAY---------TAYCARTGYCAYYTNTGYTTYTCNAAYTTYCARAGYGARTTYYTN TTYMGNYTNCAYYTNGCNACNCAYGGNGCNTTYAARCAYGTNTCNCAYGTNTCNYTNAAR MGNGGNYTNCCNYTNTGYCCNAARTGYGGNTAYGTNGCNGTNAGYAGYAAYGAYYTNGCN CARCAYYTNAGYMGNCAYATGAARGARMGNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGTAYMGNAGYGCNTAYATGACNGAYGGNCCNCCNCCNTAYCAY CCNGCNGCNATGAARCARTGGGCNAAYAARGTNYTNAGYTTYTCNACNCARTAYAAYAAY AGYGGNTGGTCNGCNAAYCARACNYTNGGNCCNCCNMGNGTNTAYCCNCARCAYGGNGAY ATHCARGGNGCNTGGGCNACNTCNATHTGYGAYAGYAAYCARTTYATHGARYTNGARTTY GARGTNCCNGTNMGNCCNACNGCNATHAGYATHTAYGARACNTAYAAYCCNGGNGCNATH GTNGCNGTNAARTAYAARAGYCCNAAYGGNAAYTGGGCNGTNATHTGGAARACNAAYTGY CCNACNACNATGMGNCARAGYMGNATHTTYTCNCCNMGNATHCCNGARGCNATGYTNCCN GTNAAYCARATHMGNATHGARATHGAYTGYACNAGYGCNMGNGAYTGGTGYGARATHGAY GCNGTNGARYTNGTNGGNATHMGNGARGGNGCNGTNGCNCCNGTNGAYGAYAGYCARTTY ATHGCNGAYATGGARYTNYTNGTNAAYAGYAARYTNYTNAGYGAYGTNAARTTYGARGTN GAYGGNAARAARTTYTAYGCNCAYAAYGCNATHYTNGCNGCNMGNTCNTCNTAYTTYGCN AARATGTTYAAYAARGGNAARGAYGAYGARGTNACNYTNAARYTNCCNAARGTNACNCAY TCNGARATHTTYTGYGTNYTNMGNTTYYTNTAYACNAAYMGNYTNCCNGCNGAYTGYACN CCNATGACNYTNATHAARYTNTGYGCNGTNTCNGARACNTTYGARGTNCCNGARYTNAAR ACNGCNGCNATGTAYAARATHGTNGARATHATGACNAGYAAYAAYGTNGTNGAYATHTAY TCNACNGCNCARAARGAYGGNAARATGGAYGAYATHCARAGYYTNTGYYTNAARTTYATG TCNYTNMGNYTNAARGARATGTCNCAYGTNCCNGCNTTYACNGCNYTNCCNCARTCNGTN ATHGTNAARATHGTNCARGARGCNACNGCNGAYYTNAGYATH------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GAYGAYGAYGAYGAYATHGARGAY GARGARGAYAGYTAYGCNAAYAAYCARGAYGGNTGYGAYGARCCNCAYGCNGTNCARTTY CARCCNMGNATHGAYAGYCARYTNTCNAARCARYTNGARGCNGARYTNGTNAAYTCNAGY YTNGCNACNGGNGTNATHAAYGAYGAYGGNYTNAGYGAYACNTTYAGYGAYAGYGGNGGN GGNGCNGARGCNGGNGTNAAYTCNAAYAARTGYGGNGCNTGYCARTGYCAYGCNTGYYTN AAYCARAGYGGNCAYATGATHTCNACNTCNYTNCCNYTNCARGTNCCNYTNTCNCCNCCN CCNGCNGARYTNCAYYTNTAYCCNCAYATHCAYGGNYTNCCNCCNCAYMGNAAYATGTTY GAYYTNCCNTCN---YTNATGCCNCCNATHAARYTNCCNATHAARYTNGAYTTYGAYGAY CCNAAYGGNATHCARGAYCARATHTAYGAYGCNTAYAGYGAYTGGGAYAAYGCNMGNCCN GGNTCNYTNGCNGCNCARTAYCAYCAYCARCAYCARCAYCAYYTN------------TCN GARYTNYTNCCNCCNGTNTCNYTNTCNACNACNACNACNCCNTTYAAYTTYGARGCNYTN ACNYTNGCNACNCAYACNACNCARACNTCNACNACNACNACNAGYGCNTTYAARTCNGTN GCNGGNAARCARGGNAAYTCNTCNATHYTNCCNAGYYTNAGYAGYATGTCNTCNGARGGN AGYTCNGTNGAYCCN---ACNAARCCNYTNGAYTTYGCNTCNYTNATHAARATHCCNCAR TCNTGYYTNAAYTCNTCNTCNTGYATHTCNTCNTCNTCNGCNGCNTCNTCNACNGTNGCN TTYCCNAGYYTNCCNGTNAGYACN---------------------CCNTCNAARTCNAGY GTNCCNTGYCAYGGNCCNCCNTGYYTNMGNCCNACNCCNYTNGGNGGNAAYGCNACNGCN AGYAARTGGGARMGNCAR------------TGYAARAARYTNACNTCNGGNYTNYTNAAY AARCARAAYCCNTCNGGNGTNGTNGARCARCCNCCNCCNCARCAYCAYCCNTTYAGYACN AARYTNCCNTCNTCNCAYTCNYTNMGNCCNCCNYTNCCNTGYTCNCAYATHCARAAYCCN CCNGCNMGNGCNGTNGTNCCNMGNCCNCCNACNGCNYTNTCNAAYGCNAAYCAYGTNCCN GCNATGGTNAAYAAYATHGGNGTNGGNACNACNACNYTNTGYGTNGAYCCNGAYTGYGAR GCNCAYCAYGAYGAYAAYTGYGAYAGYGTNGAYGAYGAYAGYTCNGARAARAGYTCNAAY ACNTCNTCNAAYCARAARGARGGNAARTAYTGYGAYTGYTGYTAYTGYGARTTYTTYGGN CAYAAYAAYACNCARGTNGCNAARACNAGYTCNAAYTAYGCNGARATHAARGAYMGNYTN MGNAARAARYTNAARAARMGNAAYGARAAYAARGAYAARACNAAYCCNCCNGTNGARGTN GARGARTCNAARGARGARATHAARAARGAYTTYYTNGAYAARCARGGNATHGARGGNYTN YTNAGYTTYATHAAYGGNACNAAYGARAAYGGNCARACNGCNAARGCNGCNAARMGNGCN MGNCARAARCARMGNAARATGGARGARAARGCNMGNACNGARAARAGY---AAYCCNCAY GGNACNAAYACNTGYCARTTYTCNGAR---------------YTNATHTTYCARAAYGCN GTNGGNYTNCCNCCNTCNTCNTGYGARYTNCARGAYCCNGCNAARMGNAARTGYCARGGN AGYMGNAAYGCNGGNAARAAYGGNTCNCARGARAARGTNGCNGCNAGYATHTCNYTNACN CARGARGTNACNMGNCCNTCNYTNGTNATHGARTCNMGNAARGCNCCNATH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGGMGNTCNYTNMGNCCN ATHMGNACNCARGCNGTNCCNAARAAYTCNYTNTTYGGNACNGCNYTNGARCARGTNGAR AANNNNAGYYTNAARTAYGTNGARGGNMGNTAYATHCCNGARGGNCARATHAARACNGCN CCNGAYMGNTAYCCNYTNCCNGARCAYYTNAARCARCARATHCCNGGNMGNCARGCNYTN GARACNAGYMGNAARGARGTNGAYGTNCARMGNAGYATHYTNAAYCARGCNGAYTCNCAR YTNCARTCNAARTCNGARAARGTNTTYGCNTTYCARGGNGTNGARAARATHCCNAARAGY ACN------MGNAGYCAYTCNAGYCARCCNATHTGGATGTCNGARAARGAYYTNGARCAY TCNGAYGCNATGAAYMGNGTNGGNYTNAAYGARMGNGGNAGYTTYAAYMGNGAYAARTAY GGNAARAARCCNCAYGTNCAYAAYTAYAGYYTNATHGGNGAYYTNYTNGCNCCNAAYATG GAYTTYAAYCCNCCNTGYAARACNACNCAR---------GARGGNACNACNAAYGGNAAR ---------AGYYTNAGYCCNGGNMGNCAYYTNCCNCAYGAYAAYATGGTN---GARAAR AAYCARAARCARAARAARCARTCNMGNAGYYTNGTNGAYYTNCCNCCNAAYATHMGNCAY ACNTTYGGNAGYMGNATHTGYGAYAAYYTNYTNTCNGAYAARACNYTNGTNGAYYTNGCN YTNGARMGNCARAARTCNAARATGGGNCCNYTNMGNCCNTCNAARAARATGAAYGTNGAR AGYYTNCCNGTNGAYATGAARGAYAAYTAYGARACNYTNGGNAAYACNACNMGNTAYAAY ATHTTYCCNGGNYTNACNTCNGGNCAYACNATHAGYCARACNCARAARGARTTYAAYGAY YTNGTNCAYYTNMGNMGNGTNCCNAAYACNGAYGARTTYMGNTAYCARMGNGAYGARYTN AGYACN---TGGTCNGARCAYAAYGTNYTNMGNGARMGNATGAARAARGCNTGG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GTNGCNGTN ATHGGNAAYTCNTGYGTNGTNTAYYTNGTNGTNTCNAARCAYMGNATGMGNAAYGTNACN AAYTAYTTYATHGCNAGYYTNGCNYTNAGYGAYATHYTNATGGCNGTNGTNTGYATHCCN TTYACNGTNTTYTCNAAYGTNYTNYTNCAYTAYTGGCCNTTYGGNCCNGTNYTNTGYCCN ATHGTNACNTAYYTNCARGTNNNNGTNGTNTTYCARAGYGCNTAYACNYTNCCNTTYYTN CARMGNYTNGGNAARMGNMGNTGYYTNCARATHGTNGCNGGNTGYTGGGTNYTNGCNTTY YTNACNAAR---------------------TTYGARTGYTCNYTNTGYAAYTTYGTNGTN GAYTAYCAYTAYAARGGNAARAARCCNCCNTTYACNAARTCNATHATGTTYYTNGARGAY TGYTAYGTNATGAARGAYCCNTTYTCNACNTCNGGNGGNTTYATHAAYGTNGGNGCNACN TGYTCNYTNTGYGGNATHTGYGTNTGYATGGCNTCNGARTGYAGYATHTTYTAYACNGCN MGNTTYTGYYTNGARTGYGCNAARAARAAYYTNGGNGARTTYCCNGAYGARGTNAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TTYGARAARTTYATG GARAARGTNAAYACNYTNCARCARTCNYTNCCNAAYCARAARMGNMGNYTNTGGAAYACN GTNAARTCNGCNGCNAARCAYGTNYTNAAYGARACNGAYCCNGARTAYCCNGTNACNATH YTNYTNTCNTCNGARGCNGGNCAYTCNCAYGTNACNGAYTGYATHGCNGAYAARGTNGCN TCNACNTTYGAYTCNATGTTYGAYACNTCNTAYGTNGTNCCNTTYACNGAYGTNAARTCN YTNAARCAYYTNAGYGGNAAYGAYCARAARYTNGARYTNGAYMGNGCNATHYTNAARGCN TTYGAYGAYGCNAARGGNMGNAGYTTYGTNATHMGNAAYATH------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNTTYTGYGGNATGYTNGTNTGYTCNTCNGARGAYCARGARYTN YTNTCNAARGGNACNAARAARGCNGARAARMGNMGNCARGTNYTNATGMGN---GAYMGN AAYMGNGGNGGNGGNGGNYTNTCNGARGCNAGYMGNTCNYTN---------YTN---TCN GGNCARGARGARATGTTYGARAARGCNYTNAARCAYMGNGAYAARYTNYTNGARTAYGAY MGNACNAGYGTNMGNMGNACNCARGTNATHGAYGAYGARTCNGAYTAYTAYGCNACNGAY TCNAAYAARTGGYTNACNAARTCNGAYMGNGARAARYTNMGNAARMGNGARGARGARYTN MGNCARGTNMGNCAYGGNTCNMGNMGNGAYMGNAARATHACNTTYGAYTTYGCNGGNMGN ------MGNGTNATHGAYGCNGARGAYGAYGCNGGNAARTTYATGTAYGAYAARGAYGAY AAYGTNATHCARGARGTNCAYTTYGGNMGNACNCCNAAYATHGAYGAYAARGGN---TTY GTNGTNAAYCCNACNYTNGAYMGNGARCCNCCNCARTTYGTNGAYACNGARGTNAGYAGY MGN---------------------CARCCNGTNMGNAAYCAYYTNGTNCARCAYCARAGY ACNMGNATHCARGAYAARGARYTNCARGARATGGGNGAYGAYGGNATGTGYYTNAGYATG CAYCARCCNTGGGCNTCNYTNYTNGTNTGYGGNATHAARATGCAYGARGGNMGNGTNTGG TAYTCNCCNCAYMGNGGNYTNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CCNGAYGAYGARATGATGMGNGGNGARATHGARMGNAAYTTYGGNYTNMGN GARYTNGAYTAYYTNGAYMGNYTNYTNGCNGGNAAYATHGAYTAYYTNGAYMGNYTNTCN MGNCAYYTNACNYTNMGNATHATHTTYTTYYTNGAYYTNGTNTCNYTNGCNATGYTNGGN CARGCNAGYCAYAARTTYMGNGARYTNTGYTCNTGYGAYGCNGTNTGGTCNAARATHTAY ATGGARCAYACNGARACNCCNCCNACNCARGAYYTNYTNATGYTNGTNGAYCARGARGGN TGGMGNGCNGTNTTYTTYATGAAYAARYTNCARYTNCARAARAAYATGMGNMGNCARGGN MGNAARGARAARGARCARMGNTCNCARTTY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNATHCCNAAYTCNTGYGTNTAYCAYGGNAARMGNACNTTY AARYTNTGYGGNYTNTTYGGNGAYCCNCAYYTNMGNACNTTYAAYGARCARTTYCARACN TGYAARGTNAARGGNGCNTGGCCNYTNATHAAYAAYGAYTAYYTNAAYGTNCARGTNACN AAYAAYCCNGTNGARGGNAAYACNGAYGCNACNGCNACNAGYAARYTNACNGTNATHGTN AARGGNAAYCCNGARTGYACNTCNAARGAYTTYCARACNTAYCARGCNCARTAYGAYAAY YTNCCNAAYACNTTYGARGAYGGNMGNGTNACNTAYGGNCCNTAYAARAGYYTNGARYTN GTNGARGTNGAYCCNGGNAARCAYGTNGARATHCAYATHMGNTAYATHGARACNGTNGTN GTNATHMGNCARATHGGNCAYTAYTTYACNTTYTCNGCNMGNATGCCNGARGARYTNGTN AAYMGNAGYAGYGGNGGNGAYYTNCARYTNTGYGTNMGNGGNTGYCCNCAYTCNGARMGN ATHGAYTAYMGNGARTAYYTNACNAARMGNAARACNMGNCAYGARGCNGARMGNGTNTGY MGNGARGCNAARGTNGTNGAYTTYTAYTTYGAYTCNTGYGTNTTYGAYYTNATGGCNACN GGNGAYAARAARTTYACNYTNTCNGCNYTNTAYTCNYTNCARGAYGTNATGAARYTNCAR CCNAAYTCN------CARYTNGTNAAYMGNTCNACNYTNGAYGAYTAYGAYMGNGARTAY GGNAGY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNYTNTCNAGYATGCCNATH YTNTCNCAYYTNATGAGYGARAGYYTNGAYACNAAYAGYMGNMGNYTNTTYGCNTCNTGY CARYTNCARATHTGGGCNGTNGARTGYYTNTCNMGNATHGCNGTNAARTCNTAYACNGAR GAYAARTAYGGNGTNGTNCARMGNTCNYTNCCNGTNYTNYTNTCNTCNYTNYTNGARYTN CAYGARGCNATGGARAARCAYTTYMGNYTNACNTCNACNGTNTCNMGNMGNTCNAAYGGN GCNGTNAAYCCNTCNGAYACNATGYTNMGNTTYAARYTNCAYTCNGCNATHAARGCNGGN YTNTAYCARATGGTNAAYACNTAYGGNACNTAYATHGAYGAYYTNMGNYTNACNGGNGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNAAYTAYGTNTTYTTYGGNYTNTTYYTNATHCAYACNATHCAY MGNGGNATHATHCAYCCNYTNGTNATGAARTAYAARAGYGCNTCNGTNCCNYTNGGNATH YTNYTNGGNGGNATGYTNCCNAAYATHYTNTAYCARTGGYTNATHGCNAAYTTYYTNGGN GTNGCNGAYTTYGTNAGYAAYTAYACNTAYGAYCCNMGNTTYYTNYTNGGNATHYTNYTN TAYGTNATHGGNTTYATHATHAAYMGNTGGGCNGAYTGGAARYTNMGNTCNYTNMGNGAR AARAARGGN------------------AGYAARGGNTAYTAYGTNCCNTTYGGNGGNYTN TTYGARTTYATHTCNTGYCCNAAYTAYTTYGGNGARYTNGTNCARTGGACNGGNTGGGCN ATHGGNACNTGGTCNYTNTCNGGNTTYGTNTGGYTNTGYTTYAGYGCNGCNACNTTYYTN GCNMGNTCNMGNCAYAAYCAYCARTGGTAYAAYGAYCAYTTYGARAAYTAYCCNMGNAAR MGNAARGCNYTNATHCCNTTYGTNTTYTCNGARGTNGGNAGYGAYCAYGARCARGCNYTN TCNMGNACNGCNAARATHGTNYTNAARGCNTCNGARYTNTTYTCNGGNACNAARGCNAAY CARGCNACNCAYTCNATHMGNGAYGARGCNGTNAARTTYYTNCCNACNYTNAAYYTNGGN YTNAARGAYYTNGAYCAYYTNAARGTNTCNGAYYTNMGNCAYAARTTYGARMGNACNAAR AARMGNAARYTNAAYTCNAAYGARAARACNATHTTYATGAARGARTGYGARACNTTYATH ACNGARYTNGTNGAYCAYMGNATHATHGARAARMGNMGNMGNGAYMGNATGAAYAAYTGY YTNGCNGAYYTNAGYMGNYTNATHCCNAGYAGYTAYCAYAARCARGGNCARGGNMGNATH GARAARACNGARATHATHGARATGTCNATHAARCAYATHGAYYTNYTNCARCARMGNGTN GAYGAYATGGARAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------ATHAAYACNMGN TTYGCNCCNTTYGGNACNAARYTNGTNCCNAGYMGNAAYYTNCAYAARGGNGGNTCNACN YTNTTYMGNTAYGGNATHAGYATGAARTGGTAYGTNGCNTGYATHGGNTGGGCNATHGCN ACNGCNACNGGNYTNGCNGTNGTNTAYGGNATHCAYGTNAAYACNTTYGGNGTNYTNCCN GCNAGYTAYTCNGTNGTNGCNYTNTAYAAYGCNYTNTCNMGNTCNGCNTGGGGNGCNGCN GTNTGYTGGGTNATHATHGCNTGYGCNYTNGGNTAYGGNGGNCCNGTNAAYGCNYTNYTN TCNTGGTCNCCNTTYGTNGTNYTNGGNMGNYTNACNTAYATGAGYTAYYTNATHCAYYTN GCNATHATH------------------TCNCCNCCNGGNCARGAYGARTTYGTNAGYGAY GCNTTYGARGCNAGYCARYTNACNGARGARGAYATHMGNMGNGARATGGARCARCARYTN MGNGTNGGNGARGGNAAYGAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AARGCN CCNCARYTNGGNGAYYTNGARATHYTNTCNATHGARCAYGAYGGNCAYGARAARAARCAY AGYTGGTAYTGYGARAARATHGARGTNACNTGYATGMGNACNYTNCARCAYTGGATHTTY CAYTGYAARGAYTGGYTNTCNYTNTAYCAYGGNGAYCARTGYATHAARMGNGAYYTNATG GCNAARMGNYTNGARAARAARAAYYTNTTYGARMGNGGNAGYGTNGAYAARTTYMGNATH MGNTTYAARGAYATHGGNGARATHAARTCNGTNAARGTNGARCAYGAYGGNMGNGGNGTN GCNGCNGGNTGGYTNYTNGAYMGNATGATHYTNCARAAYACNGARCARATHAAYGCNATH TAYTAYTTYYTNYTNAAYGGNTGGYTNGCNMGNGAYGTNGGNGAYGGNAARYTNTGGMGN GTNATHAGYGTNAARAARAARYTNGCNAARGARATHACNACNGGNAARCCNGTNAAYTAY CARGTNACNGTNMGNACNGGNGAYGTNMGNTAYGCNGGNACNGAYGCNAAYGTNTAYATH ATHATHACNGGNAGYAARGGNAARACNAARAARYTNTTYATGGAYGAYTCNMGNAAYAAY TTYGARMGNGGNACNACNGARTCNTTYGAYYTNACNACNGTNGAYGTNGGNCCNATHTCN MGNATHCARATHGGNCAYGAYAAYTCNGGNCCNGGNGCNGGNTGGTAYTGYGARGAYGTN GCNGTNACNAARTTYYTNCAYCAYGARGARGTNGCNGCNTTYYTNAARGAYYTNAARAAR AARACNAARTCNAARGAYMGNCAYMGNMGNMGNYTNTCNCARAARYTNAARGCNAARTCN CARCARGAR---------------ACNGARGARCARGARAGYGAYGARGARACNGAYYTN GAYGARGARAAY------------------------------------------------ ------------------------------------------------------------ ---------------------GCNAGYCARGCNGTNCARMGNAGYYTNGCNATHGCNACN GCNAARTTYAARMGNGAYTAYCARCARCARAARYTN---AARAARCAYTGYATGTTYTTY AGYMGNTTYGGNAARTGYAARMGNGGNGARAGYTGYCCNTTYATHCAYGAYCCNAARAAR GTNGCNGTNTGYACNMGNTTYYTNMGNGGNAARTGYGAYGGNGAYAARTGYCCNTTYTCN CAYGARGCNTCNGTNCAYAARATGCCNGTNTGYYTNTAYTAYYTNMGNGGNGCNTGYAAY AARGARAARTGYCCNTAYYTNCAYGTNAAYGTNAAYCCNGCNGCNCCNGTNTGYAGYGAY TTYAARCARGGNTAYTGYTCNYTNGGNGAYAARTGYAARAARYTNCAYTCNTTYGTNTGY CCNACNTTYGCNGCNCARGGNAAYTGYCCNMGNGGNGARAARTGYTCNATGYTNCAYMGN TCNAGYMGNAARATGCCNGTNYTNTCNATHTCNACNAAYYTNCCNMGNGAYTCNATHCCN AARGAYTTYYTNMGNMGNGCNTCNGANTAYYTNNNNTCNGARYTNGGNAARCCNNNNNNN NNNNNNYTNGTNCANGTNNNNCCNGAYCARATHATGAGYNNNGGNGGNNNNCARNNNCCN TGYGCNAAYGTNNNNYTNGGNNNNATHGGNNNNGTNGGNCCNGANAARAAYMGNAGYATG GCNNNNNNNNNNTCNNNNYTNNNNNNNGAYNNNYTNGGNATHCCNAARNNNNNNTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATHGARTTYAAYACNATHGCNGCNAGYTTY GGNGGNYTNACNCARAAYATGAGYAGYYTNCAYMGNYTNACNATGGGNATGGCNGGNATG CCNTTYTCNGAYGCNCARATHCCNGAYAAYAGYCCNGCNTCNGGNYTNGCNYTNGGNATG GTNAARGCNTGGGARYTNTAYGGNAAYCCNGAYGCNGCNATHGTNTTYGTNGTNAGYCAR GCNGARMGNAAYATHATGGAYCARMGNTGGYTNGARTTYGARATHYTNAARYTNAAYCCN AARATHMGNGTNYTNMGNMGNGGNYTNYTNGAYTTYGARGCNMGNGGNATGYTNGAYTCN GARAGYAARYTNYTNATHGAYGAYTAYGARGTNGCNATHYTNTAYYTNMGNGAYGGNTAY ACNAAYGARAAYTAYTCNTCNCARAARGARTGGGAYGGNMGNYTNAARATGGARYTNTCN AARGCNGTNAARTGYCCNTCNGTNCARTAYCARYTNGCNGGNGCNAARAARATHCARCAR GARYTNGCNMGNCCNGGNGCNYTNGARCARTTYGTNTCNGAYYTNGCNATHATHGAYYTN YTNMGNAARACNTTYGCNGAYCARTAYAGYATGGAYYTNGGNGARGARGGNGAYAARGCN GTNGCNYTNGCNYTNAARTTYCCNGAYAARTTYGTNYTNAARCCNCARMGNGARGGNGGN GGNCAYAAYYTNTAYAARGAYGAYATHACNAARTTYATHGARGARCAYAARGAYTCNAAR GARMGNAAYGCNTAYATHYTNATGCARMGNATHTTYCCNTGGGARCARMGNAAYTAYYTN GTNAARACNGGNGTNCCNTTYGCNYTNTCNACNATHATHAGYGARATHGGNATHTAYGGN GTNTAYATHGGNACN--------------------------------------------- ------------------------------------------------------------ ---------------AARAAYTAYATHCARGARAGYAARTCNATHGARTGYAARGAYACN GARGARGGNGGNACNYTNGAYAAYTTYAGYAAYGTNYTNTCNGCNMGNACNGCNGTNGGN CAYGAYGCNGARGGNAARATHCAYATGGTNCARGTNAAYGGNMGNACNAAYGARYTNGGN GTNAGYYTNCCNGARTTYGCNGARYTNYTNGTNAGYTTYGGNYTNGTNAAYGCNATHAAY YTNGAYGGNGGNGGNTCNGCNACNGTNGTNGTNAAYGAYACNYTNATHAAYTAYCCNACN GAYMGNTGYGARAGYATHTAYACNTGYCCNMGNGARGTNTCNACNGTNYTNTGYGTNCAY ACNCCNGTNTGYACNCCNGARGAYTGYTCNGGNCAYGGNGCNTGYGARYTNGGNACNTGY AARTGYMGNGGNGCNTGGCARGGNYTNGCNTGYGGNTGGATGGGNCAYGAYTGYTCNATH GCNTGYACNCCNGGNTGGMGNGGNGTNAAYTGYTCNGTNCCNTGYGTNTGYGGNAARGGN GGNAARTGYGAYCCNGCNACNGGNMGNTGYCAYTGYTGGCCNGGNTAYACNGGNMGNTTY TGYGARTCNGTNTGYCCNTAYAAYYTNTAYGGNCCNCAYTGYGARGGNGTNTGYTTYTGY AAYAAYAGYTGYTTYTGYGAYCAYGTNACNGGNAAYTGYCAYAGYTCNCCNMGNAAYTCN GAYTAYATHAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYGCNGARGCNCCNCCNCARTAYACNGARMGNACN AAYGTNTCNCCNTCNGARGGNAGYCCNCCNGCNTAY------GCNACNGTNGARCARGAR CCNCCNCCNTCNTAYGAYTCNYTNTAYGGNMGNGTNAARGCNGCNAARAGYGARTCNAGY AGYATHYTNGGNTTYTTYAARAGYTTYYTNATHATHATHYTNTCNACNATHGGNTTYACN ATHYTNYTNGCNATHTTYATGGCNGTNCCNGTNTCNATGATHGTNATGGGNGCNATHTAY YTNGAYGAYTGYCCNGCNGARMGNATGATHCCNATHTAYYTNATHGTNGCNGGNTGYTTY GGNGCNGCNAARAAYATHTTYAGYATHGTNCARMGNTGYMGNAARACNGARGARGARMGN CARGARGAYCARAARAARGTNAAYCCNGTNGARTCNYTNGTNAAYTGYTTYATHTTYGCN TGGTTYATHGCNGGNTGYGTNTAYATHTAYMGNACNAARGGNGAR------TTYAGYGAR ACNGTNGGNGCNCCNGAYTAYTGYGAYCCNGAYYTNTAYTGGTTYGCNTTYTGGATHACN ACNTCNGTNTAYATHATHATGGGNYTNAGYTGYYTNTGYGTNTGYTTYGGNGGNTGYYTN GCNGCNTGYTTYTCNGGNGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CARAAYGTNGGNAAR AGYTAYACNGCNGTNATGTAYTGYYTNACNTGYATHGARTCNTGYGTNAARAAYTGYGGN MGNMGNTTYCAYATHCARGTNGCNAAYAARGAYTTYYTNCAYGAYYTNATHAARATHATH GGNCCNAARAAYGAYCCNCCNCARATHGTNCARGARAARGTNYTNAGYATGATHCARACN TGGGCNGAYGCNTTYMGNGGNAAYTCNGARYTNAARGARGTNGARAARGTNTAYCARGAR YTNAARCARAARGGNATHGARTTYCCNATGACNGAYYTNGARAAYATGGCNCCNATHCAY ACNCCNGCNMGNAGYGTNCCNGARCARACNGTNAGYCAY---------GAYMGNGGNGGN AGYAGYCAYGGNGGNTAYGTNCCNGCN------------------------CCNGCNACN TAY------------CCNACNAAYCARAGYGGNGGNGGNGARCCNYTNAAYGCNGAYCAR ACNACNAARYTNMGNMGNGARYTNGARGTNGTNCARGGNAAYATHMGNGTNATGGGNGAR ATGYTNACNGARYTNAGYCCNAAYAAYGTNGAYTCNTCNGAYYTNGARYTNYTNCARGAR YTNAAYMGNACNTGYMGNCARATGCARTCNMGNATHGTNGARYTNYTNAAYGARATHGCN ACNGARGARATHACNATHGAYYTNYTNMGNGTNAAYGAYGAYYTNAAYAAYGTNTTYYTN MGNTAYGARMGNTTYGARMGNTAYMGNACNGGNCARTCNGGNCARGCNTCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARACNCCNTCNMGN GCNTCNYTNAAYCCNTTYYTNCCNGARMGNCCNCCNAAYCCNCCNCCNYTNAGYGCNGCN AARTCNAGYTCNYTNMGNGCNAARGGNGTNGARAAYTCNGARAAYAAYACNYTNGARAAR CARAARAARAAYYTNAAYCCNTTYYTNACNGAYGAYGARGARGARMGNTGYMGNCARTAY GARGTNGGNGTNAARGGNAARCARTGGCCNATHTTYTAYAGYCCNGARTAYAAYATHGGN TTYTGYGGNYTNGARAARYTNCAYCCNTTYGAYGCNGGNAARTGGGGNMGNATHATHGAR TTYYTNAARGAYGCNGGNATGYTNMGNGAYGAYACNATHATHCARCCNTTYGARGCNAAR GARGARGARYTNYTNYTNGTNCAYACNAARAGYTAYYTNAAYAGYYTNAARTGGAGYATH ACNGTNGCNGGNATHACNGARGTNCCNCCNGTNGCNYTNYTNCCNAAYTTYATHGTNCAR AARAARGTNYTNMGNCCNTTYMGNTTYCARACNAGYGGNACNATHATGGCNGGNAARYTN GCNYTNGAYMGNGGNTGGGCNATHAAYGTNGGNGGNGGNTTYCAYCAYTGYTCNGCNGAY MGNGGNGGNGGNTTYTGYGCNTAYGCNGAYATHACNYTNGCNATHAARTTYYTNTTYGAR AARGTNGARGGNGTNTCNAARGTNATGATHGTNGAYYTNGAYGCNCAYCARGGNAAYGGN CAYGARMGNGAYTTYATGGAYGAYAAYMGNGTNTAYATHYTNGAYGTNTAYAAYMGNAAY ATHTAYCCNCAYGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNTTYGCNMGNYTNGGNGGNTCNGCNGCNTTYYTNGGN CCNGARGAYATHCAYYTNGGNGTNAAYGARACNGTNCARGAYTCNGCNMGNGTNYTNGGN MGNATGGCNGAYGTNATHYTNGCNMGNGTNTTYGGNCAYGAYATHYTNGAYACNYTNGCN AAYGARGCNTCNTCNCCNGTNATHAAYGGNYTNTCNGAYYTNYTNCAYCCNYTNCARATH YTNGCNGAYTTYATGACNATHCARGARCAYTTYGGNTAYYTNMGNGGNGCNAARATHGCN TGGGTNGGNGAYGGNAAYAAYATHYTNCAYTCNYTNATGTAYGGNTGYGCNAARYTNGGN ATHGAYYTNAGYGCNGCNACNCCNCCNGGNTAYGARCCNGAYCCNGAYATHATGGCNGAR GCNATGAARATGGCNGGNAARACNGGNGCNTCNTTYCARATGGGNGAYGARCCNYTNAAR GCNACNTAYMGNGCNGAYGTNGTNGTNACNGAYACNTGGGTNAGYATGGGNCARGARGAR GARAAR---CARAARMGNYTNAARGAYTTYGCNGGNTAYCARGTNAAYMGNAARATGATG AARGARGCNGGNGCNGAYTGYATHTTYYTNCAYTGYYTNCCNMGNAARCARGARGARGTN ACNGAYGAYATHTTYTAYGGNAAYGARTCNATGGTNTGGCARGARGCNGARAAYMGNATG TGGACNGTNATGGCNGTNATGYTNCAYYTNATHCARCCNTAYACNCCNACNATHCCNATG CCNAARTAYGTNMGNGGNATGTCNGARGCNTCNGCNTCNCCNAARMGNTCNMGNYTNGAY TTYGAYGAYGGNGGNAARGAYGAYCAYTAYGARAARTTY---AARAGYMGNGAYATGGAY GAYCARGTNGTNYTNACNCARGGNAARMGNAARMGNGTNGARYTN------GAYGAYGAY GAYYTNAARGAYTCNGARGAYGGNAARTCNAARGTNATGAGYATGGAYGCNGCNMGNMGN GARCAYACNTTYGTNATGMGNYTNGCNAAYAARGARCARGARYTNCARGAYTGYATGAAY CARATHCARGARATGAARCARGCNCARACNCARAAYACNGCNCARYTNMGNTCNYTNYTN GAYCCNGCNATHAAYYTNAARYTNAARGTNAARCARAAYGARYTN--------------- ---------------------------------------------------AGY------ ------------------------------------------------GCNTGGAARTTY ACNCCNGAYAGYCARACNGGNATGMGNYTNATGACNMGNTGYMGNATGYTNCAYCARGAR AAYGAYGARYTNGGNAARATGATHTCNTCNGGNMGNACNGCNMGNYTNGARGGNGARATH TCNYTNCAYAARGCNYTNGTNGCNGARATGAARAARAAYCARAARGARYTNGTNGARTTY GTNGGNGARYTNGARGARGAYGTNGARGGNATGCARGGNATGATHYTNYTNYTNCARGAR CARYTNAARGARGCNMGNGARCARATHTCNCARYTNCARCARGARAAYGARGTNYTNMGN AAYTCNCAYAAYCCNACNAAYCCNGARCCNGGNGGN------------GARTCNMGNGCN GAYTTYGCNATHATGGARGAYTAYTGYAARTTYCCNAARGAYAARGCNYTNTCNTCNYTN GARMGNGTNTTYGAYAAYGARMGNGGNGARGAYGARATGAARAAYATGGARTTYCAYMGN GGNGARGTN---TCNACNTAYGTNGTNAARCCNGTNGARAARATHAARMGNGGNGAYGAY ACNCCNMGNACNGARAGYYTNAARAARMGNYTNACNAARTCNGCNAARATHMGNGGNGCN TCNYTNTAYTTYACNATGGAYGAYCAYGARMGNGGNTTYGARAARGARTGYGTNCARCCN GTNGTNGAYGARGTNGARACNTAYATHAARTCNACNGAYTCNGCNGAYGARAGYGARYTN TCNCCNCCNGCNAGYAGYMGNYTNGAYTCNGAYGCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATH GARGARGGNYTNGARCARGAYCAYAAYTCNGARAAYATGGGNCCNGGNCCNMGNGCNTAY ACNCCNGAYCARTCNGAYYTNAAYACNTTYGTNYTNMGNCCNGCNCARCARGGNATHACN ATGAARTGYMGNATHACNMGNGAYAARMGNGGNGTNGAYMGNAAYATHTAYCCNACNTAY TTYYTNCAYYTNGAYCARGAYAGYGGNMGNAARGTNTTYYTNYTNGCNGGNMGNAARMGN AARAARAGYGCNACNTCNAAYTAYYTNATHTCNACNGAYCCNACNGAYYTNTCNMGNAAY GGNGAYTCNTAYTGYGGNAARYTNMGNTCNAAYYTNYTNGGNACNCARTTYACNYTNTTY GAYCAYGGNGAYAAYCCNAARAARAGYGGNCCNGAYGCNGCNMGNCARGARYTNATGGGN GCNGCNTAYGARACNAAYGTNYTNGGNTTYAARGGNCCNMGNAARATGACNATHATHATH CCNGGNATGACNAGYGARCAYYTNMGNGTNAAYATHMGNCCNCAYGGNTCNCAYGAYAGY YTNATHGARAARTGGAARMGNAARGAYATGGARAAYYTNYTNGARYTNCAYAAYAARACN CCNGTNTGGAAYGAYGAYACNCARTCNTAYGTNYTNAAYTTYCAYGGNMGNGTNACNCAR GCNTCNGTNAARAAYTTYCARATHGTNCAYGAYAAYGAYGTNGARTAYATHGTNATGCAR TTYGGNMGNGTNGCNGARGAYGTNTTYACNATGGAYTTYAAYTAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNGTNAARYTNYTNGCNCAYCCNGAYGCNTTYATHAARMGNGTNGCNGGNGARATHATH GCNACNCAYGGNGAYAARCAYTCNGAYYTNGCNYTNYTNGCNACNAAYACNYTNATHCAR GAYTGYAARGAYGTNAAYCCNGTNATHMGNGGNYTNAGYTTYMGNGTNATHGGNTCNYTN AARTCNTCNGTNGTNTCNGARGTNYTNAGYTCNGCNATHATHGCNGGNYTNGGNGAYAGY AAYGGNTAYGTNMGNMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG GCNTCNGCNTCNCARTGGGARGTNGTNGGNAARAGYAARAARACNAARCCNACNCAYAAY GGNTTYACNAARTCNCARAARAARCARTAYATGGARAARATGCCNMGNATHGARCCNAAY GCNCCNYTNAARGARGARAARAGYYTNTAYTCNGCNYTNGARGARAARGARAARYTNGAY CAYGGNAAYGCNGCNAGYGCNMGNTCNTCNGAYGGNGGNAAYAAYATHAARAARCCNGCN GTNCARAARAARAARAARCCNGAY---GAYGGNAARAARCARGARAARCCNGTNCCNYTN GAYGTNGCNYTNGARAGYYTNGAYCAYACNGAYYTNGARAGYATHYTNAGYCARTCNCAR YTNMGNTTYCCNGAYCAYCARGARGTNTGGYTNAARGAYYTNGCNTCNTAYYTNAAYATH AARYTNGAYMGNGTNCARGARACNGAYCCNACNTTYAARGGNAARTCNCCNAGYTAYCCN YTNGAYACNATGTCNAARAGYTAYACNAARGTNYTNAAYAAYTTYATHAARAARTTYTCN CAYACNATGYTNGARCARGTNTTYTAYTAYTGYATGCARACNATGYTNCARGARTCNGCN AARGGNAAYCCNGTNTAYGGNTAYAARGCNTTYYTNCARYTNYTNATHCAYCAYAARCCN AAYATHGCNYTNGGNAARYTNCCNCARTAYYTNGARYTNYTNAARACNCAYCARAAYAAY TCNTTYMGNTGYYTNTCNATHYTNTGGGTNGTNGGNCARTGYGGNGTNAARGAYTTYAAR AGYGGNYTNAARGTNTGGYTNGAYYTNATGYTNCCNGCNYTNGARGTNAARCARGTNGCN CAYTAYCCNGTNGAYTAYYTNGARAARYTNGTNAARACNCAYGAYTCNYTNAGY---TCN ------------GGNTAYGGNGTNGTNACNYTNMGNGARTAYTTYCARGTNYTNGAYATH GTNTTYAGYCCNMGNTTYAAYYTNTCNAAYGARYTNMGNCARMGNYTNATHTCNYTNTAY CCNCAYATHAARGAYYTNGCNTAYGGNGARAARCCNTCNCARACNYTNMGNACNTTYTTY CCNTCNTAYYTNGCNMGNTTYATGTCNGCNTCNAAYGARGCNGTNAARACNGARYTNYTN AAYTGYATGACNAARTGYYTNACNACNGAYAARCARTCNTTYAGYGTNTGGTGYCARYTN TAYATHAAYCAYYTNGCNGCNTCNGGNCAYYTNYTNGARCAYATHAAYTAYGARTGGGAY AARYTNTCNTCNCARTTYGAYAARAARYTNYTNAARGARACNYTNMGNTCNTTYTCNGTN ACNAAYGARGARYTNGARAAYCARGGNMGNGGNAAYMGNGCNGGNYTNGGNYTNTGYCAR GCNGCNACNAARCAYYTNCARGCNMGNATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYMGNATHCCNGTNCARGGNGARACNATHTAY GAYCAYCCNTCNATHGTNTTYGGNGGNATGAGYGAYGGNACNGTNCAYGCNACNGARACN GARTCNTAYYTNCARGGNAARACNATHTCNMGNGCNGTNYTNCARGARGCNATGMGNYTN YTNAARAAYGARYTNAAYCCNGARGCNCAYGARYTNYTNGCNTCNCCNAARTAYMGNAAR GAYGGNCARCCNGTNMGNGTNAGYACNAAYYTNCCNTCNACNATHACNYTNAGYGGNAAR MGNTTYCCNATHYTNGCNAARTAYAARGCNGGNTTYAGYAAYAGYGGNCAYGTNCARGTN ATHGARGTNAAYYTNTAYGCNGAYATHGGN------------------------------ ------------------------------------------------------------ ---------------TTYYTNTTYTCNAGYYTNGGNCAYGGNAGYYTNCCNCCNYTNACN CARGARMGNGCNATGCARYTNYTNGARYTNCCNGARCCNTAYAAYGARATHAARTTYGGN TCNTTYACNGGNAAYYTNACNYTNATGAARTGGTTYMGNAARTTYAAYGCNCAYTTYAAR GTNCARGGNCAYTGYTAYATHATGTAYAARCCNGTNGGNAARAAYAARACNCCNGGNGTN CAYAAYGARACNGCNYTNGARTCNYTNAARMGNGGNYTNCARGAYAGYAGYATGGCNTTY ATHTAYCAYTGYGARAAYCAYTAYTTYTGYCCNATHGGNTTYGARGAYACNCCNMGNMGN TCNAGYCARGCNTAYGARGGNTCNYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGGARGAYTGGCARAARGTNYTNGGNGTN TTYCARCARACNGARACNAGYYTNTCNAARTCNAARGARYTNCAYYTNGTNACN---GAY MGNATGCAYCARGAYTCNTAYCAYAARYTNTCNGARCARGCNYTNAAYYTNGCNGAYGAY GGNYTNCARAAYTAYACNAARGCNTCNMGNGAYAAYAARCARYTNACNCARATHYTNCAR TCNAGYYTNGARGARYTNAARTCNCARAARGARGCNAARCARMGNACNGTNCARGARTTY CARAAYGAYYTNGARCAYYTNGCNTCNGARAARAAYATGYTNTCNAAYTCNGCNATHGAY ACNACNGAR---GCN---AARGTNCAYAARYTNGARGARGARGARMGNATGTTYCARCAR GARYTNGGNYTNCARYTNAARAARGTNAARGGNGGNAAYYTNCARATHGCNTTYACNCAR ATHGAYCARGARMGNCCNGAYYTNAARTTYYTNTTYTGYYTNAARATHGAYGCNGAYMGN AARTAYATHGTNAGYGAYTGYCARCCNCCNATHGCNGAYGTNCARAGYYTNGTNGAYGAR YTNAAYGCNGGNAARGAYYTNCAYAARTTYGTNCAYYTNATGMGNMGNCARTTYMGNACN ATH--------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------GCNGGNGTNYTNAAYGARTCN ATHTGGAARACNATGATHGARGTNAAYYTNGCNGCNYTNGTNCARGGNACNCARYTNGCN CARGCNCAYATGMGNAARGAYAARGGNGGNAARGGNGGNMGNATHATHAAYATHAGYTCN ATHGCNGGNYTNYTNGAYTCNTTYACNATGCCNATHTAYTGYAGYACNAARCAYGCNGTN MGNAGYTTYACNATHGGNATGGCNGGNCARCCNAAYYTNGARTCNCARGGNATHGARTAY GCNGTNYTNTGYCCNGAYCCNGCNGAYACNGARYTNATGAAR---YTNGAYAARTCNAAR ATGCAYGGNTTYGAYCARGTNTTYCCNTTYYTNGARGGNAARAARACNAGYGTNGARAGY GTNGTNGARGCNTTYYTNCAYYTNYTNACNYTNGAYAARATGAAYGGNGGNATGYTNYTN GTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYACNCCNGARAARCCNAAR GGNAARGGNGAYGARGGNMGNAGYAARAARGGNGAYCAYGARGAYMGNGGNAARTCNAAY MGN---------------YTNTTYGTNMGNGGNCCNTAYTAYTTYAARGCNTTYMGNACN GARATHMGNAAYACNATGTTYGTNAARTCNAAYGCNCCNGAYCCNAARYTNYTNGTNACN ACNGTNTTYGARYTNYTNATHAAYAARAARCCNYTNAARTCNGAYTGYATHAAYCARYTN GCNCCNGTNCAYGGNATHTGYGARTAYGAYTAYMGNCARYTNGARGTNATGGCNMGNMGN GTNYTNGCNCCNTTYTTYGARACNAGYGTN---GARCCNCCNAGYTTYTCNGTNYTNYTN TTYGAYAARATGMGNGARGCNGGNGCNGAYATHTGYGTNGARACNATHMGNAGYGTNGTN TGGAGYYTNAAYCCNTGYGCNTGYCARTCNTCNYTNYTNTCNGARCCNGAYGTNGCNATH MGNYTNGAYGTNGTNGGNAGYAARATHTCNYTNGGNGTNYTNTCNAAYTAYATGAARTAY MGNCARTAYAGYCCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATHACNGCNGTNAARATG YTNCCNGAYATGAGYGGNATHAAYGTNTAYTGGAARTGYAAYMGNTGYGAYGAYGAYAAR YTNAAYCARYTNYTNGTNTCNCAYCARAARAARYTNMGNAGYYTNYTNYTNTCNTAYMGN ATHYTNGGNCARACNCCNMGNGTNACNTTYGTNAARGAYACNGCN---AGYTCNGAYGTN GGNCARYTNAAYAGYYTNTTYGAYMGNGCNGAYTAYGGNCCNCCNTAYGARCCNAARCAY ACNAARGARACNTGYYTNTCNACNAARTCNCAYAARGCNGTNAARGCNGARACNTCNGAR AGYMGNAAYGARATHMGNGGNGARATGGARGARAAYAAYGGNGARGAYYTNGARTGYCAR AARGARGGNGTNGAYGARATHAGYCAYYTNAAYATHTTYTGYCAYAARGGN--------- ------GAYYTNTCNGGNAAYACNTTYTCNGARGARAGYATGAAYTTYCARAAYAAYGTN TAYGGNYTNGAYMGNGAYACNYTNATHAARAARGTNATHGCNAARAARAGY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GCNYTNAGYCAYCAYGCNGGNGTNGTN GTNGAYGAYMGNTTYATGGTNYTNATHGGNGGNTGGGAYGGNAARCAYMGNGTNTCNGAY GTNAAYGTNTAYGAYGTNCARGARGARAARTGGATGAARATGAGYACNTCNGGNTTYCCN GARGGNGCNGGNYTNAGYTCNCAYACNGTNGTNYTNYTNAAYAAYMGNAAYATHGTNATH GTNGGNMGNGARGGNAGYYTNMGNATHGARMGNAARYTNGGNAGYGCNTAYYTNYTNAAR GGNGARGTNYTNTCNGGNCARTTYGTNTAYCAYGARTAYAGYGAYAAYGTNACNTCNMGN TCNGGNCAYACNACNTCNYTNATHGGNAAYAAYYTNTAYATHATHGGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNATGGARGGNCARATHYTNAARTTYACNAAYGTN ATGAARGGNTTYCARTAYMGNTGGYTNGTNYTNGAYCCNGAYTCNGGNATGYTNGARTAY TTYGARAARGGNGARCAYAARAARCARMGNCCNMGNGGNTCNATHCAYYTNGCNGCNGCN TTYGTNTCNCCNTCNGARGARGAYTCNCARACNTTYGTNGTNAAYGCNGCNAAYGGNGAR ATHTAYAARYTNMGNGCNTCNGAYGCNMGNGARMGNCARYTNTGGGTNGAYCAYATHMGN TCNACNGCNGARTAYCAYACN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CAYGTNAAYYTNMGNTGGTGG GCNGARCCNTTYGCNGTNGGNYTNTCNGTNGTNYTNATHGAYATHCCNTTYGAYATHATG GGNATHAARYTNYTNTGGTGGACNTGGCAYGAYGAYGAYCCNAARATHTAYGAYMGNCAY TAYTGGGTNCCNTGGACNTCNTAYTAYTTYCAYGCNACNTTYGCNTCNTCNTTYACNTTY ATHTTYTTYGGNYTNMGNMGNYTNYTNMGNCCNTCNGGNYTNAARTTYCARAGYTGYGGN TGYTTYMGNGARYTNGTNGTNYTNATHGTNTGYGGNYTNTTYTCNATGCCNYTNGGNGCN ATGCARTTYGTNCCNGTNTAYCAYCCNYTNCAYGAYTCNYTNGGNATHCAYTCNGARGTN TGYGTNYTNYTNYTNYTNTCNGTNTAYGCNYTNACNGTNTGGAGYGCNGAYMGNTAYCCN TTYGARCAYTCNMGNGTNGCNGGNGTNGGNGTNYTNAAYATHYTNTTYGTNGGNYTNTTY YTNCAYTAYGTNTTYTAYGTNTGGYTNGTNTTYACNGCNAARCCNCARCAYATHMGNTCN ATHGGNTAYCAYCARCCNGTNGGNTCNTGYAAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGAAYYTN TAYTTYGGNMGNAARATHACNTAYGARATHGGNGTNATHATHGGNYTNGCNGCNTGYATH TGGYTNTAYTTYYTNGGNCAYMGNGAYCCNATGATHTAYGGNTGYGCNGTNYTNATGGGN GCNGCNGGNTCNGTNYTNYTNATHACNTCNYTNTCNATGACNTCNGAYYTNATHGGNTCN AAYACNGARACNGGNGCNTTYGTNTTYGGNGCNATGAGYTTYACNGAYAARYTNTCNAAY GGNATHGCNATHTTYGTNATHCARAARYTNCAYCCNTGYACNAAYTGYTGYCCNGCNTGY GARCCNTAYTAYMGNTAYGTNCARACNTGYGTNCCNGGNGGNGCNYTNYTNYTNGCNACN ATHGCNYTNTTYYTNATHYTNTCNCARAGYATHGGNGTNCARCCNAAYAARMGNGGNTAY ATHCCNACNATHTTYCAYACNGCNTCNATHTGGYTNACNYTNGCNYTNGCNGTNCARMGN TAYATHTAYGTNTGYCAYTCNTTYAARGCNMGNACNTGGTGYACNATHAAYAAYGTNATH ATHGGNACNGTNGTNATHTAYGCNGTNTCNATHYTNACNCAYATHTCNMGNTTYTTYGAY MGNTAYCCNCARAARGTNCCNAARMGNTCNYTNYTNAAY------------------GAR GARGARGAYGARTCNCAYYTNCCNCCNGGNGTNMGNAARMGNAAYMGNTGYCAYAGYAGY AGYAGYGGNTCNGARGAYGARGGNCARAARAARCCNCARGAYAAYGARTCNTCNGAYTCN GARTCNGAYGGNGAYAAYACNTTYTCNAARCCNGARACNMGNGTNGCNGCNGAYTCNAAY TCNAARCCNGARTCNACNAARTCNCCNAARGTNMGNAGYAGYMGNTCNCAYTCNMGN--- TCNAARTCNMGNTCNMGNTCNMGNTCNCCN---MGNAARAARMGNMGNMGNTCNTCNGAY MGNAGYMGNMGNTCNMGNTCNMGNTCNCAYGAYMGN---GAYMGNGARMGNMGNMGNMGN AARGARMGNMGN---------------MGNMGNCCNMGNMGNTCNAAR---TCNCAYTCN MGNTCNMGNTCNMGNGARMGNMGNMGNTCNMGNGAYMGNGAY---MGNAAYMGNCAYMGN AGYGAYMGNAARMGNAGYMGNAGYMGNGGNMGNTGYGAYMGNAGYMGNGAYAARMGNAGY AGYMGNGAYAARAGYMGN---MGNAGYMGNAGYMGNMGNAARMGNGARMGNACNGGNAGY CCNAGYAAR------GTNATHAARTAYGGNGAYACNGTNATHAARCCNGGNGCNAGYTTY GGNMGNCCN------TCNAAY---TTYGCNAARCCNYTNACNTTYAARGARAARATGMGN CARCARYTNATHAARGCNATHGARGAYGGNACNGAYATGACNCARGCNYTNACNTAYAAY GAYGGNACNGCNATHTGYACNCAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNATHCARGAYCCN---------GARGAYGAYCARGARCAR GAYAAYAAYGARGARGAYGCNGTNATHATHACNGARYTNCARAAYGGNAAYGAYGGNGCN ACNGCNYTNTCNACNAAYACNAAYGGNGCNACNAAYGARGARATHCCNGAYAARAGYACN ATGACNGARCCNGAYATGCCNGTNCCNACNGTNAGYGGNTCNAGYGCNAARCAYCAYCCN GARTTYYTNGCNAARTTYCCNGAYGGNMGNATHCCNTCNTAYATGCARGTNCCNAGYYTN CCNMGN---TCNGGNGARAAYYTNGGNAAYCARAARAARCCNGAYAARGGNTGYACNCCN YTNGARCCNGGNAARGARTCNACNATHYTNMGNGCNATGGCNGGNTTYTCNYTNCCNYTN GARAAYATHCCNGAYTGGGCNAARAAYATGTCNGAYGAYCARTGGAARCARCARGTNYTN ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GCNGCNTTYAAYATHCARATHTTYGGN ACNAARAARATGGGNAARAGYGAYGTNTCNGAYATHYTNGCNCARATHYTNCARMGNTAY GAYYTNATHYTNATHCARGARATHMGNGAYAGYTCNGARACNTCNYTNGAYMGNYTNTGY ACNMGNYTNGAYACNGAY---GAYCCNTAYGAYGTNGTNGTNAGYGARMGNYTNGGNMGN ACNAAY---AGYAARGARCARTAYGCNTTYATGTAYMGNACNAARMGNYTNTCNGTNAAR GARACNTAYCARTAYGAYGAYGGN---GCNGAYACNTTYCARMGNGARCCNTTYGCNGTN MGN---------TTYTCNTCNCCNACNACNGTNATHGGNGAYTTYGGNATHATHGCNATH CAYACNGAYCCNGGNGAYGCNGTNAARGARATH--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARMGNACNGGNGGNAAYCCNYTNYTNAARAAYAGY GAYTTYGAYGTNCAYATGYTNGTNACNCARGARAGYTAYGTNGTNTCNGTNAAYGGNCAR YTNTTYTGYACNTAYAARCAYMGNATGGCNTTYACNTCNGCNCARTAYATHACNATHGCN GGNGAYGTNCARATHAARTTYGTNCARACNYTNGGNCAYACNGAYAAYCCNCCNCCNTAY TCNGARACNGTNCCNATG------------------------------------------ ------------------------------------------------------------ ---AGYGTNATGCCNMGNAAYTCNCARGCNCARCCN------------ATHCCNGGNGCN YTNGTNCCNGGNAARATHATHTGYATHGGNGGNATHCCNAGYCCNTCNCCNAGYAGYTTY GCNATHAARYTNATGTGYGGNCCNTCNGARYTNGGNGAYATHGCNTTYYTNYTNGAYGTN MGNTTYAAYTCNGGNTAYGAYMGNAAYCARATHATHMGNAAYAAYMGNCARGGNGGNATH TAYGGNGTNGARGARMGNCARGTNCCNCAYTTYCCNTTYTTYCCNAAYACNCCNTTYGAR ATHATGYTNYTNTGYGARCCNTCNTGYATHAARGTNGCNGTNAAYGGNTTYCAYTAYYTN CARTTYTCNCAYMGNATHYTNCCNACNCARMGNGCNGAYCAYGTNATHATHGAYGGNGAY TGYGCNGTNACNAARYTNCARATHCAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNAARATHYTNATHGARTCNTGGYTNCARAAR ATHGGNAARAARAARMGNYTNCCNAARAARGARGTNGARYTNAAR------AGYCCNATG CARYTNTTYGARTAYATHAAYCAYYTNCARGAYYTNTCNCARCARYTNAARCAYATHTCN TCNGARGTNAAYAAYYTNGAYTGYYTNYTNTCNGTNTCNGAYAAYTCNTCNTGGCARTGY AAYTGYACNAAYATHGARGARATGAARACNAARTGGTCNAGYTCNAARTTYYTNYTNGAR GAYAAYYTNGTNCARCARATGGARACNAARYTNAARAARATHMGNYTNAARMGNGGNACN YTNAARMGNGCNMGNAARGCNMGNTTYGARGARAARCARMGNMGNGARTAYAAYATHCAR GARAARCAYGCNGCNATHGAYAGYTGGCARGARGCNATHMGNAARGARATHAARGAYGAR AARYTNMGNAARGARMGNAARGARTCNGCNGAYMGNACNYTNAGYCARGTNACNAARGAR ATHCARGAYGCNAAYMGNYTNGTNGARACNATGACNGCNYTNGARAARYTNMGNYTNATH MGNMGNGAYGCNGCNCARAARMGNGGNGAYGCNGTNYTNGGNGARTCNMGNCARAGYTTY CARCARAARATHTCNGAYATGACNMGNYTNATGAAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TCNAGYGTNGAYGAYYTNATHAGYGAYATHYTNGAYGTNGAYGTN ACNGAYAGY---------------------TCNCARTCNAARAARGCNTCNAGYAAYACN TCNTCNGCNAGYCARGTNCARAGYGARAGYCARAARTGYTTYCCNGTNTTYYTNGGNGGN AGYAGYGGNGARCCNGGNMGNGGNACNACNGTNAAYGTNMGNACNTGYGAYCARYTNMGN TGYACNTCNTGYGAYTTYMGNATHTGYCARTTYAAYAAYCARGCNTGGGCNAARGAYACN GAYTAYYTNTTYYTNMGNAAYAAYGTNCCNAAYGCNGAYAARYTNAARTCNAARYTNGGN MGNAARAARGGNTGYMGNGCNTAYTGYTGYCARTGYTCNTGGCARAAYGTNAGYGARYTN GCNGARYTNAARGAYCCNTGYYTNAARTGGGTNTGYGGNAARCAYGAYTCNCCNGCNAGY GTNATHGARGCNYTNGTNTGYTTYTTYTCNATHTGGTCNGTNGTNGGNYTNGCNGGNTTY CAYTCNTAYYTNACNGCNTCNGARYTNACNACNAAYGARGAYATHAARGGNACNTTYACN GCNMGNMGNGGNCARGAYAGYTTYAAYCCNTTYAGYAARGGNTCNYTNTTYAARAAYTGY YTNGGNATHYTNTGYGGNCCNACNCCNCCNAGYYTNYTNGARMGNMGNGARTTYGTNGTN CCNGARCCNGARGCNATHCCNAAYACNATGAAYACNGGNACNAAYACNATGACNGAYGCN GCNGTNGTNGTNACNACNGTNGARACNAAYCCNGARAAYATHAARAARMGNGAYATGATH AGYTAYCARTCNCCNGAYGGNACNATHAAYAAYAARGTNCCNTCNATHAAYGGNACNGGN GTNAAYATHGGNCAYMGNGTNAAYATHTAYCCNTCNTCNCAYGGNGGNGTNAAYTAYTAY MGNGAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TGYCCNTAYAAYGGNTCNCAY YTNATHYTNCCNYTNMGNATGCCNGGNCAYYTNATGAARTGYMGNAARAAYTAYCCNGAY GTNGAYYTNGCNGTNTGYCCNTTYAAYGCNGTNCAYGARATHCCNGCNYTNGARYTNAAR CAYCAYATGACNGARTGYCCNGAYMGNAAYYTNYTNGARMGNGAYTTYGCNGAYAAYGCN YTNAAYMGNGTNTGYTTYAAYYTNCARGTNGARMGNATHAARGGNAAYACNGAYYTNCCN ---YTNCCNAARGARTAYCCNTTYCARGGNCARAAYYTNGARAAYTGGGAYGAYGAYGAR GAYGARGAYMGNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------YTNCCNGARGTNCCN CCNGAYACNGCNGARACNAAYGCNGTNATGMGNTTYGAYCARYTNCCNACNTTYTCNGAR ATHTCNCCNGAYAARTGYGTNGCNGCNTGYGCNAARYTNGCNATHGARTAYGARACNCAR YTNGARAARCAYATHGARTCNYTNAARGAYYTNAARAARGARAARACNTTYGAYAGYGTN TAYAAYACNYTNGARGARACNGCNGTNCCNYTNAAYACNGCNTGGGCNACNGTNAARAAY YTNCAYTAYGTN------TCNGAYGGNTTYAARAARGCNTTYACNMGNATHCAYCCNCAR GTNGARMGNGCNAARAAYGARMGNTGGGCNGAYGARACNYTNCAYAAYGCNTTYAARGAR YTNAARGCNAAYAGYGCNAAYYTNACNCARCAYCARAARMGNYTNGTNGAYYTNTAYYTN YTNGARGGNAARYTNAAYGGNATHGCNYTNCCNCCNGAYMGNMGNTCNTCNYTNGTNGAY GCNYTNAARYTNGTNTCNAARGARAGYAAYAAYTTYMGNAAYMGNGTNMGNATHTGYACN GAYATGTTYACNCAYGAYGTNTCNGAYTTYAAYATHYTNGARGARATGCCNTGGCCNYTN GTNGTNCARATGTCNAARGAYAARTCNAAYCCNACNMGNGGNCCNTGGMGNACNACNYTN CARCCNTCNAGYTAYCARCCNATGATGACNTAYTGYAARGAYMGNYTNACNMGNTGGAAY YTNTGGAAYGCNTAYCAYAAYMGNGCNTCNCAYATHCAYGCNTCNTCNTTYYTNAGYAAY AAYAARYTNATHGARAGYATGMGNYTNTAYMGNYTNGAYGTNGCNAARATGYTNGGNTAY GARACNTTYGCNGARATGTCNATGGARACNAARATGGCNGGNTCNGTNGARAAYGTNYTN AAYATGATHGARACNYTNMGNATGMGNTTYTTYCCNGTNGTNGGNGARGARATHGCNCAR YTNCARAARTTYGCNGARTCNGARGGNTTYAARAAYAARYTNGARATGTGGGAYATGAGY TAYTGGCARMGNMGNCARMGNGARCAYYTNTAYAGYTTYGAYAARGAY---GTNGCNGAR TAYTTYCCNGTNAAYACNGTNYTNYTNGGNYTNTTYAAYYTNAGYACNAARYTNTTYGGN ATHACNTTYGARGARGTNGCNCARGAYGTNGAYGTNTGGAAYTCNGAYGTNMGNYTNTTY AAYATHTAYGARGAR---AAYGGNGARCAYATHAGYTCNTTYTAYYTNGAYCCNTAYGAY MGNCCNGARAARCARTCNTCNGCNTAYATGGAYATHGGNMGNGARAARAGYAAYYTNGTN GGNACNTGGCCNTAYTCNTAYATGTCNYTNAARATHCCNAAR------GCNTAYAGYGAY AGYGGNYTNATGMGNTTYGARGAYATHCARACNYTNTTYCARGARTTYGGNAAYGGNYTN CARCARYTNYTNACNAARGTNCCNTAYAGYGARATHTCNGGNCARAARAAYATHGARTGG GAYGCNGTNCARGTNTGYGCNAARTTYATGMGNCARTGGYTNACNGTNCCNTCNGTNGTN AARAGYYTNAGYGCNCAYTAYAGYACNGGNGARCARATHCCNGGNGAYYTNATHATHAAR ATGYTNAARGCNTCNCAYCAYTCNTAYAAYTTYGARATGATGTAYCARYTNTAYGTNTCN ACNTTYGAYATGGARATHTAYYTNACNAARTCNCAYTGGMGNACNATHATGCCNCARYTN TGG--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CAYYTNGARGAYAAYAAYYTNGTNAAYACNCCNMGNCCNTGYCAY TAYMGNATHCCNAAYTTYGARGGNGCNGCNCARGCNAAYGAYMGNYTNACNGGNYTNGAR GCNTTYAARCARGCNAARACNGTNAARGTNAAYCCNGAYAARCCNCARGARCARGCNMGN TTYYTNGTNYTNGAR------------------------------GCNCARAARAGYYTN YTNGTNCCNACNCCNCARYTNAARACNGGNYTNYTNAAYMGNGTNGTNCCNCCNGTNGAY GCNAAYAARGAYCARYTNMGNCAYTGYTGYACNTCNCARGGNGTNAARGAYAAYAGYGTN GARGTNGGNYTNGARTCNACNGTNAARYTNGAYATGATHTTYGTNGGNAGYGTNGCNGTN TCNMGNAARGGNTAYMGNATHGGNAARGGNAARGGNTAYGCNGAYYTNGARTAYGCNATG ATGMGNACNATGGGNGCNGCNGAYGARAARACNGTNGTNGTNACNTCNGTNCAYGAYTCN CARGTNGTNGAYATHGAYGARGARYTNGTNGARGARCAYGAYYTNACNGTNGAYTAYATH YTNACNCCNACNGARYTNATHGARACNAAYTGYCARMGNCCNAARCCNGARGGNGTNATH TGGAAYCAYYTNGARGTNACNAARTTYTTYCARATHCCNGTNYTNMGNCARYTNMGNGAY ATHGARMGNGARAAYGGNAARAAYGTNCARYTNAARGAYCARAARGARGARGAYGARGAY CCNYTNGAYAGYCARGARCCNCCNMGNCARMGNMGNTAYMGNTAYAGYMGNGGNGGNTAY MGNGGNGGNMGNGGNCAR---MGNCCNTCNMGNTAY---MGNMGNGGNGGNGGNGGNGGN MGNMGNMGNCCNATGGAYAGYGARGAYAGYAAYAARGARAAYGTNGARACNGGNGAYGAR TCNGGNCCNGAYGGNGAYCAYGAYGGNMGNGGNMGNMGNCCNMGN--------------- AAYTAYMGNAAYMGNMGNTTYMGNMGNGGNGGN---------AAR---MGNGTNTCNGAR TCNGARCAYAGYGAYGGNGGNGTNGARGGNGGNCARGGNGAYGGNGAYGAYMGNCCNMGN CARMGNGGNTAYCCN---AAYMGNMGNMGNTTY------AAY---ACNMGNMGNMGNMGN TTYGARGGNAGYMGNMGNGGN---GARCAYMGNGGNTAYGCNGAYCAYTCNGGNAGYGAY GGNGARCARAARACNTCNGGNGAYGARGAYGGNGARMGNAGYCARTCNCARMGNCCNMGN TTYMGNACNAAYCCNGAYGCNGTNGTNTTYYTNGGNTCNYTNTCNMGNMGNATHMGNGTN AGYGARYTNAARACNGARYTNMGNAGYAAYAAYATHGCNCCNCARMGNYTNYTNTGGMGN GGNGGNMGNGGNTTYGCNTTYYTNTTYTTYATGGAYGTNGAYGCNGCNAARGAYGCNGTN ------------------------------------------------------------ ---------------------------------------------------AARCARATG GGNACNATHGGNTTYGAYMGNCCNACNGTNYTNMGNGARACNGTNCARTTYTAYYTNCAR TAYAARCAYTAYTGGAGYAGYCAYGAYTAYGAYMGNATHTCNAAYATGGTNGTNGARYTN TTYCCNGARTTYAARGAYGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ACNGTNGCNTTYYTNCCNCAYTGYGGNAARGCNYTNTAYAAYAAYYTN GTNTGGGCNAAYYTNTCNGGNATHCAYAAYGTNATHYTNGTNGGNAAYAGYTTYTCNYTN YTNCAYGARMGNGTNCCNTCNMGNGTNYTNAARAARACNGGNAAYTAYATHYTNAARATH YTNCCNCAYACNGTNGARAGYCCNTTY---CCNGTNTCNCAYAARTTYGAYGAYGTNTTY AAYGAYATGTCNATHCAYACNTTYCCNAARTCNAARATGCCNAARACN---GCNGARTTY TGGGARAAYYTNGAYGARCCNCARTAYGARGARGAYGARGCNGARATHGTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNGGNAARGCNATHGARTCNGARGCNTCNGARATHYTNGGNGGNGGNATHAARAGY MGNGTNGTNGTNAARATGYTNMGNGAYGAYGCNACNAARCARGAYCARAARCARYTNATH GAYGARTCNTTYCCNTAYMGNTCNATHGARCAYACNAAYATHYTNMGNGTNYTNGGNYTN TGYACNGARGCNTCNCCNTAYYTNGTNGTNYTNGARTTYGCNYTNAAYGGNACNYTNAAR ACNTAYYTNCARCAYCAYMGNCAYAAYMGNGAYGAYYTNYTNAARAARAAYMGNYTNAGY AGYTTYGCNYTNAAYGCNGCNTCNGGNYTNGCNTGYYTNCAYMGNCAYAGYTTYATHCAY AAYGAYYTNGCNGCNMGNAAYTGYGTNGTNATGACNGAYTTYACNGTNAARATHGGNGAY TAYGGNATHTCNGAYGAYYTNTTYAARGAYGARTAYTTYAAYACNATHAARNNNYTNYTN CCNATHMGNTGGATGGCNCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNGGNAAY AAYTTYAARGAYAARGGNMGNTCNAAYGTNAGYGCNTTYYTNTAYGGNGAYGGNGAYGGN GGNCAYGGNCCNAGYGAYAARATHYTNGGNMGNYTNGARMGNYTNCARGAYTGYGAYGGN YTNCCNAARGTNAARTTYAGYGAYTCNAAYGARTTYTTYTCNTAYATHGARAARGARAGY CCNAARATGYTNTGYMGNTGGMGNGGNGARYTNTAYYTNGARYTNCAYAAYGGNAAYTAY ACNACNTGGGGNAARGTNAARAARGGNAAYMGNAARTGYGARATHYTNYTNCARGAYGCN GARTTYGCNTGYACNATGGCNGCNYTNAARACNACNGCNTTYATHTAYCCNMGNAARGAR YTNGARMGNYTNTGGAARYTNYTNYTNYTNAAYCARTTYCAYGAYGTNYTNCCNGGNTCN TCNATHACNCARGTNTAYGAYGAYGCNATHGCNTAYTAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARGCNGAYCCNAAYCARYTNTGGCARTGYTTYTAYGCNTGYGTN YTNYTNYTNATHATHYTNACNGGNYTNAARACNMGNATGGCNGAYACNYTNTGGGAYCAR GARATHGARTCNGGNYTNMGNAARACNGCNCAYAARGCNYTNTCNATGATGAARACNATG MGNTAYAARGTNACNACNGAYAGYGTNTCN---GCNGAYGTNTGYGCNATHTGYYTNGAR GARTTYGTNAAYAARCARAARYTNMGNGTNYTNCCNTGYTCNCAYYTNTAYCAYACNMGN TGYGTNGAYMGNTGGYTNGTNCAYAAYMGNACNTGYCCNYTNTGYAARYTNAAYATHYTN ------------------------------------------------------------ ---------------GGNAARGTNMGNGARAARMGNYTNATH------------TTYAAY TGGGTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ACNATHGCNGAYATHTTYATGTTYTAYAGYYTNCAY AAYGTNYTNAAYMGNATGACNTTYCARGAYAARGARAARTAYATHAAYGTNTCNMGNTGG TTYGGNAAYGTNCARGARGAYGCNCARGTNMGNCARTCNYTNTCNTCNGTNAAYTTYGTN MGNACNYTNYTNTAYAAY------------------------------------------ ------------------------------------------GAYAAYGTNGGNYTNYTN GTNGARCCNTCNTCNCCNAARTAYGTNAGYAARATHATGYTNACNAAYGAYYTNACNYTN GCNGTNATGGARGARGCNAARGAYAAYACNGTNGAYYTNATHATHTCNTAYCAYCCNCCN ATHTTYAAYCCNYTNAARMGNYTNACNCARAAYTCNTGGAARGARAARGTNGTNATHGAY TGYATHGARAAYMGNATHGCNYTNTTYTCNCCNCAYACNTCNTAYGAYGCNYTNAARGGN GGNGTNAAYGAYTGGYTNATHTCNGCNTTYGAYGTNAARAARTCNAGYATHGCNCCNATH GARGCNACNCARATH---TTYCCNGGNMGNTCNCAYACNTTYGARGCNGAYYTNGARCCN GCNMGNATGAARGAYTTYTGGMGNGAR---YTNACNAGYTGYYTNCCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYAARMGNACNGTNCARAAYCARAARTCNTTY GTNTGYGGNAARTCNACNAAYTGYTCNGTNAAYYTNTCNAAYMGNAARAARTGYCCNGCN TGYMGNTTYAARMGNTGYYTNGCNATGGGNATGAARYTNGARGCNATHMGNCAYGAYMGN ACNMGNGGNACNTCNGCNAGYAARTCNCAYMGNAAYYTNGTNGCNATHYTNAAYCAYGAY YTNCAYAARCARACNCCNAGYGCNGGNAARCCNYTNGTNCCNGARYTNYTNMGNGAYATH ATGAAYYTNGARCCNYTNYTNAGYGAYGAYGARATHCCNGCNGARTCNATHYTNGARAGY CCNTAYCCNGAYCARGCNYTNTAYGCNTAYATGATGCARYTNGCNGARYTNMGNYTNTAY AARYTNGTNMGNTGGGCNMGNAAYYTNCCNCARTTYGGNGCNATHACNACNGAYGAYCAR ATHYTNYTNYTNCARAAYTGYTGGTCNGARYTNATHGCNATGAAYCARYTNMGNGAYTAY YTNTAYGGNMGNGAYYTNAAYAGYMGNACNGTNGTNCCNAAYGAYGCNCAYACNGARAAY ATHYTNGARCAYATHAGYGAYAARTCNGAYCCNYTNGTNAAYGAYAGYMGNGTNTAYAAY ATGYTNYTNAARGTNGTNCCNYTNCARGARGGNGAYTGYYTNGGNTGYAARYTNGTNGGN ACNACNGCNATGGCNTTYAGYGGNATGYTNGTNYTNGCNTCNGCN--------------- ---YTNTTYGCNGAYGAYATGGCNGCNGTNGTNACNGGNAARGAYYTNGARGARGCNACN ACNAARGCNCARMGNGTNYTNAAYATHATHGAYGAYTGGTCNACNGCNTGGGGNYTNMGN YTNTCNMGNACNAARACN---TGYTAYATGATGACNGTNMGNGGNAARCARGCNCCNCCN AARATHTAYTTYCARAAYAAYGGNACNCCNGTNNNNTAYGANNNNAAYCCNATGTTYYTN GGNGTNNNNTTYGAYGARAAYGTNNNNTTYAANNNNCAYYTNNNNTAYNNNNNNNNNMGN YTNNNNNNNMGNNNNNNNGTNNNNAARGCNYTNNNNGGNACNNNNTGGGGNTGYATGGCN NNNNNNYTNMGNNNNGTNTAYYTNACNNNNGTNYTNCCNGTNNNNACNTAYGCNYTNGGN GTNTAYCCNNNNYTNACNAARNNNNNNNNNNNNGARNNNCANNNNNNNCAYAAYNNNGCN GCNMGNNNNATHNNNGGNTGYNNNAANNNNNNNNNNNNNNNNNNNYTNYTNAARATHGCN MGNYTNTGGCCNATHMGNCARACNATHGAYTAYGARTCNTCNYTNYTNTAYGARMGNYTN CARMGNATGGARAAYACNACNGGNAARMGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNYTNACNGARTAYCARGARGAYATHGCNGARATHYTNGGNGARGCNGCN CCNYTNGGNYTNCAYATGYTNGARGARATGGARGARAARYTNACNAAYYTNGARGAYAAR ATHAAYCAYTAYGCNGAYCARATHGTNACNGAYGTNAARMGNCCNTCNMGNYTNGCNGAY MGNYTNTTYCAYTCNCCNTCNMGNACNTTYATGACNGARATGTCNGARTCNGAYGCNYTN AARTCNCAYMGNAGYTCNMGNGGNCCNMGNAGYGTNGAYYTNGTNGAYACNATGYTNGAR ACNMGNAARMGNAGYYTNGAYTAYTAYGCNTTYCCNGGNTTYGTNCAYGGNGARTTYATH GARYTNCCNGCNCARYTNGARGCNCCNCCNGTNYTNCAYAARGTNACNAAYACNCARAAY TTYAAYCCNGGNTTYAARAARTTYTGGAARAARYTNTTYYTNTCNGARGCNTCNTCNGCN GTNATGCARGAYTCNTTYTGGTGGATHTTYYTNGAYAARTTYAAYAARGARGARGGNYTN AARGARGAYAARGAYTGYYTNTTYGAYMGNATHGCNGAYAGYTAYGTNGCNYTNTTYACN AGYATHAAYACNGAYGTNAARGAYAARTTYYTNTCNGTNTAYCCNGAYTGYYTNTCNCAR GCNYTNTTYTGYTCNTAYAARGARGCNTTYCCNGARTCNAARTGGMGNTTYGAYGARGAR TTYAARCARTAYYTNGTNAAYYTNGTNTAYGARTGGGTNACNGGNYTNMGNCCNGTNCCN GGNATGTGGMGNACNTGGGAYGAYGARAGYYTNCARYTNAAYCARACNAGYAAYGARAAY GARACNGCNAARAARATGYTNGARGCNGCNGCNYTNAAYAARAARGTNGARGTNAAYYTN GAYATGGAYTCNTTYAAYAARACNATHGAYMGNYTNGGNACNGARGTNTCNGGNTCNCCN GTNGGNGGNATHTCNMGNGARATHACNAARACNACNAAYMGNATHTCNYTN------CCN TCNMGNGGNMGNTCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARGAYATHTTYYTNYTN CCNCAYGTNGGNTGGATGYTNYTNATHTCNTCNGGNYTNATHTAYATGACNGTNACNACN GTNGCNCCNCARGCNYTNCCNCCNTCNYTNGGNACNYTNACNAGYTTYGGNCAYTTYATG GGNTAYCARCAYTCNAAYATHTGYTAYYTNATHTCNTAYGTNGCNYTNTTYYTNCAYTGY ATGGARGCNGGNTAYGCNGGNAARATHTGYCARGAYMGNGGNTAYTCNYTNATHTGYACN GCNATGTGGACNTTYTCN------------------------------------------ ------------------ACNTCNGGNAARTTYATHATGTTYGTNGAYGCNCAYGTNGAR ATGAAYGTNAAYTTYYTNCCNCCNYTNATHGARACNATHGARYTNGAYTAYAARACNGTN GCNTGYCCNGTNATHGAYGTNGTNGAYAARTCNAAYTTYGCNTAYAAYATHCARGGNGGN TTYMGNGGNGCNTTYAAYTGGCAYTTYGTNTTYCARGGNCAYGAYYTNCCN--------- ------GCNGTNTAYGARCARTCNTCNAAYCAYCCNAAYCCNGTNATGGTNGGNTGYGCN TTYGCNATHAGYMGNMGNTGGTGGGARGARATHGGNMGNTTYGAYCCNGARYTNCAYATH TGGGGNGGNGARCAYYTNGARYTNAGYTTYAARACNTGGATGTGYGGNGGNAAYATGGTN AAYGTNCCNTGYTCNMGNGTNGGNCAYYTNTTY---------MGNCCNGTNACNTAYGAY YTNAARAAYGTNTCNACNMGNAAYACNYTNMGNGTNGTNMGNGTNTGGGCNGAYGARTAY ATHGARYTNATGTAYGAYMGNCAYCCNGAYYTNMGNATHTGGAAYGTNGGNGAYYTNAGY AGYMGNYTNACNYTNMGNGARAARYTNGGNTGYAARCCNTTYAGYTGGTAYAARMGNGAR GTNTAYGAYGTNGARYTNGARAARYTNCCNGAYTTYACNGCNTCN--------------- ------------------------------------------------------------ ------------------------ACNTCNMGNGTNAARAARAAYGAYAAYCARAARCAR MGNMGNCCNYTNMGNGCNAARGARGCNGARMGNAAYMGNMGNYTNGGNGCNGTNCARACN CCNCCNMGNCARAARCCNTCNGCNGAYAAYTCNTTYTTYTCNGTNAARAGYACNGARAGY AAYGARAARAGYGAYGTNTTYTTYTCNGCNGAYTAYGCNGCNMGNGCNYTNCARGAYCCN ACNAARAAYGAYATHGGNAGYATGATHCARGARATGGARTCNTAYYTNCAYTGYATHGAR AARATHGARGARMGNATGYTNACNGAYGGNCAYACNMGNTTYYTNCARCCNMGNGTNAAR AGYAARAARMGNGAYGGNTAYYTNGAYCARYTNGCNGAYMGNGAYMGNGARAARAARMGN GCNGGNGARCARAGYACNMGNTCNGCNMGNAAYGTNTAYAAYATGYTNCARAARYTNAAR CARYTNMGNAARGARGTNTCNCARTCNGAYATGAGYAARCCNACNAARAARAGYCARATH ATGTCNCARYTNGCNGTNATHCAYMGNGGNGCNGTNMGNGCNYTNCARGTNTTYGTNAAY CARYTNCCNTAYCARGAYYTNAAYTCNGGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TTYGAY GAYGAYGAYGAYGAYAGYYTNTAYGGNGAYCAYYTNTCNAAYAGYTGYTTYGCNGCNYTN MGNATGGAYMGNMGNGAYAGYGAYGAYTTYGAYGAYGAYYTNMGNTCNYTNGARTGGYTN CARAAYGARGAYYTNYTNAARAAYATHGGNGGNGARAARYTNGAYAARGARGAYGAYGAY CAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CARATGACNGTNTAYTCNGCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNTGYYTNYTNGCNYTNATHGCN------ ---------------GTNATHGGNYTN------------------GTNCARTGYCARMGN GGNTTY---------------------------------------MGNCCNGGNCARACN GCNGAYGGNTGYTAYGGNAARGTNATGGAYYTNTTYTTYATHYTNGAYTCNTCNACNTCN ATHTAYGTNAAYGAYTTYMGNMGNGARCARAARTTYGTNMGNGAYATHGTNMGNCARYTN GAYATHAGYCCNTCNGCNACNMGNGTNGGNTAYYTNACNTTYAGYGAYGARATHCARMGN CCNCCNGTNTCNYTNAGYMGNGCNMGNAGYYTNCARGARGCNATHGCNAAYGTNAAYGAY GARAAYYTNCCNTAYMGNACNGGNGTNACNAAYACNGAYTTYGCNATHMGNTAYGTNMGN GARGAYCARGARTTYMGNCARGAYATHACNAARGTNATGGTNGTNATHACNGAYGGNGGN TCNMGNTCNMGNGGNAGYACNGCNMGNGARGCNACNYTNGCNAARGARGCNGGNTTYTAY ATGTTYGTNACNGGNATHGGNACNTAYYTNGAYGARATGGARTGGMGNTCNATHGCNAGY GAYCCNGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CARCCNTCNGCNCCNGTN------CCNGARAARCAYGARCCNYTNATHAGYTTY ---GAYAGYCCN---CCNAGYCARTCN------GAYTCNCCNGTNTCNYTNTCNAAYATH ATHCCNGARCAYCCNATHGARCCN---ATHCAYAAYAAYYTNCCNCARCCNTCNGCNCCN GARTCNGAYGARCAYAARGCNATHGARTCNGARAARGARACNGARGTNGARAGYGTNMGN GTNAARGARCARACNTCNGAYTCNGTNGARAARACNAARGGNTCNTGGYTNAARGGNGTN GAYCCNMGN---------------------------------GTNATHGAYYTNATHTAY TGGMGNGAYGTNAARAARACNGGNATHGTNTTYGGNACNATGATGGTNGTNYTNYTNTCN YTNGCNATHTTYTCNYTNATGAGYGTNGTNGCNTAYYTNTCNYTNGCNGCNYTNACNGTN ACNTTYAGYTTYACNATHTAYAARAARGTNATGGGNGCNGTNCARAARTCNAGYGARGGN CAYCCNTTYAARCCNYTNYTNGARATGGAYATHTCNYTNMGNGARGAYAARYTNAARAGY GTNATHCARAGYGTNYTNAARAAYGTNAAYTGYACNYTNAGYGARYTNMGNMGNYTNTTY YTNATHGARGAYATHGTNGAYTCNATHAARTTYGGNYTNYTNYTNTGGGTNYTNACNTAY ATHGGNGCNTGGTTYAAYGGNATGACNYTNGTNATHYTNGCNGTNGTNYTNYTNTTYTCN YTNCCNAARGTNTAYGARACNTAYCARGTNCARATHGAYAAYTAY--------------- ------------------------------------------------------------ ------------CCNYTNCAYAARTTYAGYTGGYTNAAYCAYCAYGCNCCNMGNTTYTTY ATHCCNGGNGARCARATHCARGTNYTNACNGARCCNACNCARTTYTAYGARGTNYTNMGN YTNAARACNMGNAARGCNAARAARMGNATHACNTAYGCNTCNYTNTAYYTNGGNACNGGN CAYYTNGARAARGAYYTNGTNTCNTGYATHCAYGARGCNTGYCAYTCNGCNATGATHTCN AGYCARCCNGARYTNGARGTNAAYATHYTNYTNGAYTAYACNMGNGGNTCNMGNGGNAAR GTNAAYTCNCARACNATGYTNTGYCCNYTNATHMGNGARTTYCCNAAYGTNAAYGTNGCN YTNTAYCAYACNCCNGAYYTNMGNGGNATHYTNAARMGNATHGTNCCNGARMGNTTYAAY GARACNATHGGNYTNACNCAYGTNAARATHTAYYTNTTYGAYGAYAGYTTYATHATHAGY GGNGCNAAYYTNAGYCAYGAYTAYTTYACNAAYMGNCARGAYMGNTAYATHYTNTTYAAY AAYTGYCCNGARYTNTCNGAYTTYTTYCARGAYYTNGTNAARAGYATHATGTCNTTYTCN TTYCARYTNGCNCCNGAYAAYACNYTNGGNYTNGCNCCNGAYTGGCAYATHCAYCCNTTY AARGAYTCNGAYAAYAGYYTNAAYTTYAARATGGCNGCNMGNMGNAARATHAARAGYTGY YTNAARATHGGNGARACNTTY---------------AARGAYGAYCARGGNGTNTCNGAY ACNACNGGNTCNTTYTCNGGNGGNAGYGAYACNGGNATGCCNGAYACNGTNGTNTTYCCN YTNGTNCARATGGGNCCNTTYGGNYTNMGNCAYGAYGARGARGCNATGYTNGAYYTNYTN AARTTYTCNGARCCNTCNGAYCARATHYTNYTNGCNTCNGGNTAYTTYAAYYTNACNAAY GARTAYATGGAYGTNATHYTNACNGARGCNAARGCNAARTTYAAYATHYTNATGGCNTCN CCNAARGCNAAYGGNTTYYTNGGNGCNAARGGNGTNGCNGGNTTYATHCCNCAYTCNTAY ATHTAYYTNGCNCAYCARTTYTAYAAYAARGCNTCNAAYGGNAARCARTCNCAYMGNATH CARYTNGTNGARTAYGARMGNGAYGGNTGGACNTTYCAYGGNAARGGNYTNTGGTAYTAY YTNCCNAAYCARCCNYTNCCNGCNYTNACNTTYGTNGGNTCNCCNAAYTTYGGNGTNAAY AAYCARTCNAARGARYTNGARGGNCARYTNACNGCNGCNGARACNMGNTGYCARATGYTN GARAARCARYTNGAYTAYATGMGNAAYATGGTNGAYAAYTCNGARAARGAYMGNMGNCAY YTNATGGARAARACNYTNAARTCNCARCARGARMGNCAYATGGGNTCNGAYYTNAARCAR CAYYTNAAYMGNYTNGCNGARYTNGARMGNGAYCARCAYAARYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNAARTGYCCNGTNGAYAGYTCNGARGGNAAR---GGNCCNTGGGTNGGNCCNGAY ACNCARGGNACNGARGARGGNAARGAYGARAARAGYGARGCNCARACNTCNGAYAGYTTY ---------------------CCNAAYGARGCNAARCCNMGNGCNMGNTTYGGNAGYMGN GTNAGYAGYGTNGARGCNGAYGCNGGNATG---------TCNACNGTNGAYAGYACNMGN CCNGAYAARGGNCAR---GAYGGNGGNGARAGYGTNGAYAGYTCNACNTCN---AAYCAY GGNGAYMGNCAYAARGGNCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGTGGMGN GCNGCNGCNGTNMGNMGNGGNAARGTNATHYTNAAYYTNGCNCARMGNAARYTNTCNTCN CARGCNAGYCARGCNCCN---CCNCCNCCNCCNCCNCCNGTNCCNCARAARTCNGGNGGN TTYAARYTNTTYAARTTYYTNGGNGTNACNATHCCNYTNGGNACNGCNGGNGTNGTNGGN TAYGCNTGGTAYGAYCARGAYTTYMGNAARCARYTNGARGAYAAYATHCCNTAYGCNAAR GARGCNYTNGARAAYATHYTNCCNCCNGAYAAYAGYMGNAARAGYGAYGCN--------- AARCCNGTNAARGCNCCNGCNYTNGARAARGCNACNATGYTNAGYGTNCARGAYAARGTN GCNACNCCNACNGARCARCCNMGNGCNGCNACNGCNAARGCNCCNGARACNTCNCCNGCN GGNACNMGNGARAGYAARATH------------GAYCCNAGYATHATHGARCAYCARGTN MGNAGYAARGARGARGARGARMGNGCNGAYAAYGCNGCNYTNGARGTNGCNATHAAYAAR ATGYTNGARTCNAGYGARAARTGGACNTCNGARGCNGTNAARGCNCARGCNCAYYTNGCN GARGCNACNAARTCNCAYACNATGGCNYTNMGNAARGCNATGGAYGAYTCNGCNGAYATH YTNCARAARGAYGCNCARTGGGARTCNGTNTCNATHGCNTAYAARGARMGNGARAAYGCN ATHATGAARGCNAAYGARTTYGTNGCNCARGCNAARAAYACNATHGARAARYTNMGNAGY GTNYTNGARGARGGNACNGGNAAYAARGTNACNAARACNAAYCCNGCNATHTTYCCNGCN ACNAARAARYTNAAYGARCAYGCNAARGAYYTNGTNYTNGTNGGNCARCARGTNMGNCAR GCNGAYAGYGARGCNAARGTNATHYTNCARTAYAARGAYYTNGTNGAYAARGGNMGNAAR CARTTYCARATGGARYTNGARAGYYTNYTNCCNGAYGTNAARYTNGGNAAYAARAGYAAR AARYTNTCNGARGARGARYTNAAYGCNYTNATHGCNCAYGCNCAYMGNMGNATHGARCAR YTNCARAARCARATHGCNGARCARYTNTCNATGGARAAYCARMGNYTNGCNAARGCNYTN GARTCNCARMGNGCNGARAAYATHAAYATGACNGGNGARGCNGTNGAYGARGARMGNACN MGNATGCAYGAYGARTTYACNGCNGARMGNCARCARYTNGARATGGARTAYYTNGTNCAY CARGARGTNGARGTNMGNAARCARYTNGCNMGNCARGCNGCNGCNCAYAGYGAYCAYYTN MGNGAYGTNYTNACNGTNCARGARGARCAYYTNAARTCNGARTTYAAYMGNCARATGAAY YTNAARATGYTNGARGARMGNGARGCNTTYCARACNGARGTNGCNGGNTGGATHTCNMGN YTNAARGGNATHGARGCNGCNGTNGAYGGNMGNGCNGCNAGYGARAARATHGCNMGNTCN GCNCARAAYYTNTGGYTNGCNTGYATHGCNYTNAAYTCNTCNATHYTNTTYGGNTTY--- GAYGARAAYGARACNATGACNCCNYTNACNAARGARGTNGAYGCNATHYTNGCNTCNTCN AAYAARCAYCCNTTYGTNGARAAYGTNGTNMGNACNATHCCNTCNGCNGCNYTNGARMGN GGNGTNCARACNGARTCNGARYTNMGNAAYMGNTTYGTNAARGTNTCNMGNGTNAGYMGN MGNYTNGGNYTNGTNACNGARTCNAAYGCNTCNYTNTAYAARTAYYTNGTNTCNTTYYTN CAYTCNTTYATHACNTTYGAYCAYGTNCAYGARGCNACNGARTAYGAYYTNATHAAYYTN GAYGAYATGGAYAAYTTYAARYTNGTNGCNCAYGCNCARTAYTGGATGGARCARGGNAAY YTNATHATGGCNGTNMGNTTYATGAGYCARYTNACNGGNGARGCNAARAARGCNGCNAGY GAYTGGYTNYTNGARGCNACNYTNYTNYTNGARACNAARCARGTNGCNAGYACNYTNACN GCNTTYGCNTCNGCNTCNGGNYTNGCNGCNACNTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TCNMGNATGTCN GARTCNTCNACNGAYTCNGGNTTYTCNTAYGAYCAYGGNMGNYTNCCNTCNTCNTCNTCN TCNTCNTCNTGYTCNTCNTAYGCNGGNAGYCCNTCNAAYTCNGGNCAYGGNAAYAGYTCN ACNGCNTCNAAYGAYACNGARCAYGAYCCNCCNGGNAGYMGNGCNYTNACNCAYCAYATH GCNCAYAAYCAYACNTAYAAYACNYTNCCNGGNCARATHCCNMGNGARGTNAARAARTAY GCNCARAARCCNAGYTCNMGNAARGGNCCNCARAGYMGNGAYCARAARMGNGCNCAYGAR YTNAARGTNCCNTTYTCNGTNGCNGAYATHACNGAYTCNCCNGTNGARACNTTYAAYGAR ATGYTNACNAARCAYGAYYTNACNGARCCNCARYTNACNYTNGTNMGNGAYATHMGNMGN MGNGGNAARAAYAARGTNGCNGCNCARAAYTGYMGNAARMGNAARGTNGGNATGATHGTN ACNYTNGCNGAYGARATGGARGAYYTNCAYAARGCNAARGARMGNYTNYTNGCNGARMGN ATGGARATGGARMGNGARACNMGNMGNATGAARGARAARTTYGGNAAYATGTAYAAYCAR ATHTTYCARTCNYTNMGNGAYGARMGNGGNCARCCNTAYGAYCARAAYYTNTAYTCNYTN CARCARTCNTCNGAYGGNAAYGTNTTYYTNGTNCCNMGNAAYATHTCNTCNGAYAARAAY TCNACN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GGNCCN ACNGAYAARCCNYTNATGYTNTTYYTNCAYGGNTTYCCNGARTCNTGGTAYTCNTGGMGN CAYCARATHMGNGANNNNTCNNNNNNNNNNMGNGTNGTNGCNGTNGAYATGMGNGGNTAY GGNGAYTCNAGYCARCCNTCNGGNGTNCAYCAYTAYAARYTNGARTGYATGGTNAARGAY GTNAARCARATHATHACNGCNYTNGGNTAYAGYTCNTGYGTNYTNATHGGNCAYGAYTGG GGNGGNGCNGTNACNTGGGCNTTYACNGGNTGYTAYCCNGARATGGTNGAYAARGTNGTN GTNATGAAYTGYCCNCAYCCNCAYGGNTTYAARAARTAYYTNCARTCNCAYTGGACNCAR TTYAARAARTCNTGGTAYATGTTYTTYGTNYTNYTNCCNATHYTNCCNGARGTNTAYATH GGNYTNAGYGAYYTNAARTTYTTYGAYATHATHTTYAARGGNAARAARGGNGGNGTNCAR ACNGAYTCNACNTCNMGNGARGAYGTNGARGTNTAYAARTAYYTNTAYCARACNATHGGN TCNMGNACNGGNCCNGTNAAYTAYATHMGNGCNGGNYTNATGYTNCCNATHCCNTCNMGN YTNTCNCARAARGTNACNAARCCNGTNYTNYTNATHTGGGGNTGYAARGAYYTNGCNYTN GARAARGGNYTNGCNGARACNTGYAARGAYTAYTCNTAYAAYYTNATHATHAARTAYATH AAYGARGCNTCNCAYTGGGTNCARATGGAYCAYCCNGAYGARGTNAAYATGCAYATHCAR GARTTYYTNGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGYTNMGNATHGTNGCNCCNYTN YTNMGNGCNGCNCCNMGNYTNCARCARGCNMGNCARATG---AGYGGNGGNCAYACNCCN GCNCAYTGGAARTCNYTNMGNCARATHTGYGARGARAGYAARAGYCAYATGAAYCAYATG CCNGTNCCNGCNGGNTCNTGGCARGARAGYTAYAARGCNAARAGYGGNAARCARAAYATH ACNYTNGCNGTNAGYATHGCNAGYGCNGTNACNACNTTYTGGYTNYTNTGGTCNAAYGGN TAYATHTAYTTYCAYTCNGCNCCNAARATG------YTNCARAAYYTNGGNTCNAGYYTN AARGTNCCNTCNAARYTNAGYAARYTNGTNTCNYTNAAYAAYGCNYTNMGNGARAARTGY CAYGCNGCNAARYTNYTNAARAARGTNTCNGTNGCNGAYCCNGCNMGNACNTTYATHGAR MGNYTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNYTNAGYTCNATGMGNACNGCNYTNGARCAR GCNAARCAYMGNATHGTNMGNYTNMGNGAYGARAAYGAYTCNAARGCNGAYATHATHGAR GARGARMGNGAYMGNMGNAARGTNGTNGARGARMGNYTNCARAAYTAYYTNATHGAYYTN TAYAARAAYCCN------------------------------------------------ ---------GAYTAYAGYAARCCNGCNCCNGTNACNTCNTAYAGYGTNTTYGGNATGCCN ACNGGNGCNGTNTAYAGYCARGCNGGNAAYGTNAGYCCNGARCARAARTCNYTNGAYAGY YTNGAYYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGYTNAARAARATHGCNAARCCNTCN CCNYTNACNCCNYTNMGNAARAGYGTNAARGAYAARGCNGAYMGNGARAGYGGNTGGGAY GAYTAYYTNATGTCNAARYTNAGYAARYTNACNGCNAAYTGGATHGTNCAYGARMGNATG CCNCARGGNAARAAYAARGAYAARYTNTCNAARACNYTNCARTCNTGGTAYGGNATHCCN ATGCAYACNGAYYTNGTNMGNGARGARATHAGYGAYGGNGARGGNAARGARAARAARAAR AARATGAARCCNAARTCNAARTGGAARAARAARGARMGNGCNYTNYTNGARMGNGTNTAY AAYGTNACNCCNCCNCCNGARGARGCNYTNGAYCCNTAYTCNGAYGAYAAYAARGCNCCN TTYTAYMGNCARCCNGCNGGNATHMGNAARAARMGNMGNAAYGARGARAARGARGARGCN GCNGCNATHAAYGCNACNGCNCAYAGYATHACNGTNMGNAGYCAYGTNAGYACNCCNCCN GTNACNYTNMGNGARATGATGACNCCNMGNGTNGGNGAYAARATHTAYGARACNGAYAAY YTNTTYGARCARGARTGGYTNACNGGNAAYAARCARGTNTTYGARCAYGAYCCNYTNCAY ATHAARATGGAYTCNCARACNMGNTAYAARAARCARYTNCARMGNGARATGCCNCARGGN CCNGAYACNTGGTGYAAYCCNGAYGAYCCNACNGGNTCNATHCCNAARCCNAGYATHTCN TGYTTYATGCCNAARAARGGNCAYAARMGNTGGACNGGNYTNCCNGARCARATHGAYAGY ACNGARTCNACNATGCARGCNATHCCNCCNGGNYTNGAYCAYGAYTAYYTNAARCCNGTN GAYCCNAARCARMGNMGNMGNTTYAARCARAGYAAYGCNYTNGTNACNATHGTNAAYGAY TGGMGNACNAARTGGTTYYTNAGYGGNCARTTYGCNGAYAGYACNCCNGAYGAYYTNATH MGNGAYATGGCNGAYATHCARCCNCAYGTNMGNYTNAARGCNATHGGNACNGTNGCNAAR GCNACNGARTAYAARCCNCCNACNGAYAGYAGYATHCARYTNGAYGGNTCNAGYAAYGAY CCNGTNACNAAYYTNCCNAARAARATHTTYGTNGCNYTNGARTGYYTNYTNGARGAYAGY CAYGARCARGTNMGNAARGCNGCNGCNATHACNYTNTAYTCNYTNAAYMGNCCNTGYGAY AARGCNCAYGARACNYTNMGNATHATGYTNGARAGYCCNAGYGGNGTNGAYMGNTGGGCN GGNGCNCARTGYYTNGCNCAYTAYGGNGARTGYGAYTCNGAYGTNGTNGCNGARATHATH MGNCARATHYTNTCNTCNGARGTNGCNATHAARTAYGARCARGGNATHCAYYTNYTNGCN AARYTNAGYAAYAGYACNAAYYTNGTNCAYTGYATGGTNGCNGARCARYTNAAYAGYAGY AGYTGGMGNCAYMGNGTNATHGCNTGYAARATHATGCCNACNYTNTCNGGNACNACNAAY MGNGAYATHACNCAYAARYTNTCNGARYTNATGTGGCAYGAYTGGCAYATGGARGTNMGN AGYGCNGCNGCNCARTGYYTNGGNAARACNAGYCAYGGNMGNGAYGTNCAYGAYGAYATH MGNGAYMGNATHATHAAYGGNACNGARMGNACNAARATGGARGCNATHAAYAARYTNGGN CARYTNGGNATHATGACNGCNAARYTNYTNCCNGCNTTYYTNGARTGYTTYTCNGAYGCN TAYGTNTCNATHMGNAGYGARGTNTGYATHACNTGYGGNAAYYTNCARATHAARGARGAR CARGTNYTNAAYMGNYTNGTNCAYYTNGCNACNTTYGAYACNATHTGGAARGTNAARGCN YTNGCNATHCARGCNYTNGGNAARATHGGNGARGTNACNGARGAYATHAARGARTGYYTN YTNTGGGCNATGMGNTAYGARGARAARGCNGGNGTNMGNGCNGARGCNTGYCAYTCNGTN GTNGARYTNAAYATHGCNGARGARGAYGTNATHGARATHYTNCARGAYMGNYTNYTNGTN GARTCNAAYCARYTNGTNMGNGARGARATGATHGARGCNYTNAGYGTNTTYGGNTTYAGY ACNTCNGAYGAYATGGAYACNGTNGCNCARATHAARTCNGARGTNMGNAARYTNTCNACN MGNAAYATHATHGCNTCNCARATHATHGTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGMGNCARCARACNTCNCAYAGYTTYCARGCNYTNGAYCCN GAYGARATHGARCCNGCNGAYYTNYTNGARCARYTNGTNTCNTCNACNAGYAGYMGNTCN CAYGCNAARAGYGGNAGYGARACNTGGGCNTGYGCNTGGGCNCCNGAYAAYTCNTAYTTY GCNTGGTCNAGYGGNMGNMGNGTNYTNAAYYTNGTNCCNTGGGAYACNAARGCNCARAAR MGNCAYGAYYTNGCNAAYACNGAYGGNYTNAAYGGNMGNAARTAYCAYATGATHGAYTGY TCNGARATHATHATHGARYTNYTNGAYCAYMGNGAYACNGTNMGNTGYYTNGAYTTYACN AARGAYGGNYTNCARYTNTCNTCNGCNTCNMGNGAYGGNTCNATHAARYTNTGGGAYYTN ACNAAYGAYGGNAAYATGTAYAARACNYTNAARCCNAAYATHAAYTTYTAYGGNTGYACN TTYTCNCCNAAYGGNAARTGGGTNGTNGGNGCNAARTCNGTNTAYATGTGGGAYMGNTCN TGYYTNAAYGAYGTNCCNAARTTYGARGGNCAYCAYAAYGAYGTNGTNAGYTGYTGYTTY TCNCCNGAYTCNTCNYTNYTNGCNACNGCNTCNTAYGAYACNAARGTNATHATHTGGAAY AGYTAYACNMGNGARMGNYTNTGYGCNYTNGGNCAYYTNTTYCCNAGYCCNMGNYTNATH TTYGCNGGNGGNTCNAAYGAYCAYTAYGTNMGNCARATHTCNTTYTCNMGNGAYGGNGTN ACNYTNGCNTCNGTNTGYGARGAYGGNTTYGTNMGNTTYTGG------------------ ------------------------------------------------------------ ------------------------------YTNCAYGARATGTGYATGTAYGTNCARGGN CAYTCNGAYACNYTNYTNGTNYTNYTNYTNGCNAARGGNACNMGNTGYAGYAARAAYTAY ATHCAYTCNYTNTGGAARTCNTGYYTNTCNCAYYTNGCNGARYTNGAYTTYGARATGAAR AAYATHGARMGNCAYCARAARGAYGAYCAYGARACNCCNAAYCAYTAYATGMGNTAYGAY TCNTTYACNCARGAYYTNCARGGNACNGCNYTNYTNCCNGTNACNAAYGTNGGNCARGAR ATHGTNGAYGCNTGYGTNAARATGCAYGAYACNTTYCARACNTGGGARGAYGTNAARGAY ATHACN------------------------------------------------------ ------------------------------------------------------------ ---------GGNAAYYTNGGNYTNAARAGYAGYCCNYTNGCNCCNACNGCNTGYAARYTN TCNTCNCARTAYYTNGTNYTNGAYCAYATGACNAAYCAYTAYAAYAARATHGCNAARGCN AARCCNGCNATHGAYAAYAARCCNCCNAGYAGYYTNGCNTCNAGYCARAARATHMGNGAY MGNAARAAYMGNCAYMGNATGATGACNGGNACNCCNACN--------------------- TAYAAY---------ACNGGNACNAARATHGARGAYGCNTTYGAYGAYGAYCCNGARGAY GAYGARGARMGNYTNGTNCARTCNATHATGMGNTCNACNYTNGGNAARACNAAYGAYGCN AGYCAYGARGCNACNTAYGGNTCNGGNTCNAARCARAAYTCNGAR--------------- ---TCNATHGAYCARAAYGGNCARATGACNAARCCNAGYTAYGCNATHCCNATG---ACN MGNCCNATGTCNGCNMGNTCNTCNMGNTCNATGCAYTCNATHGCNTCNGGNTCNGTNACN TCNYTNGGNACNCAYGAYGTNGTNAARGCNACNTAYAAYGGNGAYYTNYTNGARAARMGN TCNCAYGTNTTYACNGARCCNGARMGNCCNTTYACNCCNMGNACNYTNAARACNAARCAY GARTCNMGNYTNAARAAYTCNAARTCNTAYAGYGCNCCNMGNTCNAARTCNGTNMGNCAY AGYATGTCNGARATGGARAARGARGAYGARAAYCARAARCCNCCNCARCCNMGNMGNMGN CCNCARCAYGGNGGNACNAAYTTYGGNGARACNYTNCCNACNAAYCARATGACNGARTCN ATGYTNATGGAYATHACNATHCARAGYMGNGAYGARCARMGNTGGGARAARTCNCCNGGN GGNGTNCCNCCNYTNGCNATHTCNATGGAYCCNGAYCAYATGAGYTGGATHCARGARCAR GCNTCNAARGCNGARGTNMGNGCNMGNAGYAGYAAYAARATHMGNTCNTCN--------- ------ATHCCNACNACNGGNGARGCNGARMGNAARMGNAGYYTNAGYAGYTCNATHMGN YTNGARACNYTNAARAARGARGARGARCARAARTAYYTNACNTTYGCNAARCARGTNACN GAYGARGTNYTNGCNMGNAAYATHTGYACNGAYAARGTNYTNCAYMGNTTYTTYGARTCN CAYATHGARMGNMGNAARGGNGAYYTNGAYGARGGNMGNATGMGNGARGTNYTNGCNGAY ATHMGNCARTCNYTNGGNYTNMGNGAYATHTCNCCNGAYMGNMGNAARGAYGTNACNTTY CAYAGYMGNGCNGCNAGYCARYTNAAYGGNGAYTCNGGNGAYACNGCNTCNTCNTCNGGN YTNTAYGGNGCNACNATGGARTCNACNTCNACNATGCARTTYGGNCARACNGGNGAYATG TTYAGYACNATHCAYTCNGARGAYGAYGARYTNGGNACNYTNMGNGARGARGAYGGNAGY GAYGARAAYGARYTNACNACNACNCARGTNYTNAARCARTAYCARATGAAYYTNACNGCN AARGAYGCNAAYGGNGARGTNAGYGARTCNGAYGCNGCNGGNGGNGARGGNACNGARGAY GAYGCNYTNGGNMGNCCNGCNACNGGNGARMGNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARAARAARYTNTGYAAYTGYGTNGTNGCNGARACNATH GGNGAYGAYGTNAARACN---ATHGGNTTYGCNYTNTAYTTYCCNATHTAYTCNACNTGG GARGGNATHTGYATGCAYATGGARGAYYTNTAYGTNACNCCNGARTTYMGNATGCARGGN ATHGGNAARCARYTNTGGAARCARGTNGCNAARATHAGYYTNGARYTNGAYTGYCARMGN TTYCARYTNAAYGTNYTNGGNTGGAAYAARATHGCNAARGAYTTYTAYATHMGNAAYGGN TGYGTNGAYYTNAAY---YTNGARGAYTGGCAYTCNYTNMGNYTNACNMGNGARGCNYTN GARAARTTY------ACNTCNTCNTCNTCNTTYYTNTCNMGNTAYMGNGARGCNGAYTCN YTNAARAGYAAYAGYAAYGARAAYATHGGNTCNYTNCCNTCNCCNMGNMGNGTNTAYGCN AGYTCNGCNGTNGGNGARGGNAGYCCNMGNCCNGTNGGNTTYTCNGTNTTYMGNGAYACN GGNAGYAAYGCNAGYACNTCNMGNTGGGAYAGYAAY---------AGYAGYGCNTCNGGN ATHGGNTCNYTNCARTCNMGNATHGCNAGYTAYCAYTCNCCNMGNTCNTCNGCNGGN--- ---ATHTCNGTNCARTCNGCNGCNTCNATGCARCARCARAAYGARAAYATHTCNCARYTN GARAARCARYTNGARAARGARMGNGARGARAAYMGNAAYYTNCARCARAARYTNGAYGAR AARGAYAARAARATHGTNGARYTNGARAARGCNATHGARYTNYTNAAYAARGARTGYGAY GGNYTNGAYGARGAYAAYYTNAARYTNCARGAYGARAAYCARGCNYTNATHMGNGCNATH TCNAARYTNACNGCNAAY------------------------------------------ ------------------ATHGTNTGYTCNMGNACNGCNCARACNGAYGAYTCNYTNYTN GARTGYTGGYTNTGYGAYMGNAARTCNAARAAYTCNAGYGARYTNTAYGAYAGYGGNCAY YTNTCNGCNAGYTTYGAYCARGARGCNTAYGAYYTNATGGTNAAYGARACNATHCCNGAR AGYTAYTGGAARGARYTNGCNGARCARMGNMGNYTNGCNYTNAAYGAYACNYTNGARGAR AAYGARAARYTNTGYAAYGARGTNGARCARYTNAARGARGARAAYMGNMGNYTNTCNGGN YTNGCNAGYGARGCNGARAARYTNAARGARATHYTNCARGGNGTNYTNTCNGGNTCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNGARACNYTNACNGAYGTNTGYCAYGAR TTYYTNATHCARTTYATGACNCAYYTNGGNATGGCNGCNGAYMGNAARGCNCARCAYGGN AAYTGYGGNTTYCCNGAYATHATGGARMGNGTNTTYTGYGAYATGGGNYTNGGNAGYGTN ACNAGYYTNCAYGGNTTYTAYCARCARMGNGTNYTNTCNTAYCAYACNAARATGAARCAR CARTGYCARAARTAYATGYTNGARTAYAGYACNYTNGTNAARCARCCNCCNYTNYTNTCN GGNCAYGGNACNGCNTCNCCNGGN---GGNAGYGAYACNYTNCCNGTNATHMGNATHAAR GARGARCCNAGYACNGARATHCARTTYCCNYTNYTNGAYGAYAAYGAYGAYGTNAAYGAY GCNGARCARYTNYTNAAYATHGARAGYYTNGGNACNTTYGARATHGTNGARCAYGARACN GCNTCNGGNYTNACNACNGARGTNGARTCNAARTGGTCNCARAAYAARGGN--------- AAYGCNGGNGARGCNMGNTCNGCNMGNCARTCNACNCARGARGARACNACNGARAGYACN GARCARAAYGTNGTNMGNACNCARTCNAAYATHCCNAARACNCCNCARTCNAAYGTNCCN YTNACNCCNCARGARGTNAGYGTNACNACNCCNMGNGARAGYAAYAGYAGYCARGAYGAY AAYGTNCARGARTCNMGNTCNGTNYTNGCNACNGAYATHTTYTCNCCNTCN--------- GCNCCNACNAARAARCARAARAARAAR---CAYTTYGAYYTNGTNACNMGNTCNACNAAY TCNACNACNAAYCARCCNAARATHGARYTNAAYCCNGCNAARGCNYTNATHGAYGARCAR GTNCARATHMGNATHAGYGGNYTNTCNMGNGGNGARAARGTNACNYTNCAYGCNTGYTTY GARGAYGGNGAYMGNYTNTAYGGNGCNTGYGGNCAYTAYATHGCNAAYGARGAYGGNAAR GTNGAYACNTTYAGYGAYGTNTCNTAYGGNGGNAGYTTYACNGGNYTNGARCCNATGGGN YTNTTYTGGAGYAARAARCCNGCNTTYGGNAARGCNGCNAARMGNATHATHAAR---GAY GTNACNACNCCNATHCARGTNCAYYTNGGNATGGARTCNGGNTTYCARYTNTTYGARGAY YTNGAYTGGACNGGNCAYATH---TCNAAYAARTCNTGYATHYTNAAYMGNTCNTAYATG GCNCCNGGNGTNATHMGNGTNCCNGTNAARGARGAYGGNTTYGARGGNACNYTNTTYATH CCNAARGGNCARGGNCCNTTYCCNGCNGTNYTNGAYGTNTTYGGNYTNAAYGGNGGNGAR YTNGARATGMGNTCNTCNYTNYTNGCNGGNAARGGNTTYGTNACNYTNTTYYTNAAYTAY TTYAARGAYAARGTNATGCCNMGNGAYGGNAAYTTYGTNGAYTTYAAYGTNTTYYTNAAR GCNTTYGAYTGGYTNGCNGCNCAYCCNGCNGTNGAYCCNAAYGCNYTNGGNGCNACNAGY ACNTGYGTNGGNGGNTCNTTYGTNTTYATGYTNGCNTCNAARMGNCCNAARGTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATHACNACNCCN YTNGGNACNYTNAARGGNTCNGTNYTNGCNTCNCCNAAYGGNAARAAYTTYGCNGCNTTY MGNGGNATHCCNTAYGCNYTNCCNCCNACNGGNGCNMGNMGNTTYGCNMGNCCNGARCCN TAYCCNATGTTYGARGAYGTNTTYGAYGCNACNAARGARGGNCCNATHTCNATHCARCCN GARGGNGTNAAYTAYAARTGGCCNAAYCARGARGAYTGYYTNTTYYTNAAYGTNTTYATH CCNATGCCNTTYGGNMGNACNACNAAYAGYAGYYTNAARAARGTNTTYGTNTAYATHCAY GGNGGNGGNTTYATHATGGGNTGYGCNAAYGARTAYGTNCCNGGNGAYYTNGTNACNGAR GGNGAYATHATHGTNGTNACNTTYAAYTAYMGNYTNTCNTGGYTNGGNTTYYTNAARGCN AARTCNAARCARATHAARGGNAAYATGGGNTTYTGGGAYACNYTNYTNGCNYTNCARTGG GTNAARAAYAAYATHGCNGCNTTYGGNGGNGAYGCNGAYGAYATHGCNATHGGNGGNGAR TCNATGGGNGGNGARAGYGTNTCNTGYYTNAGYATHATGCCNCARGCNAARGGNYTNTTY ACNNNNGGNATHNNNATGAGYGGNNNNNNNNNNNNNNNNNNNTCNACNNNNGGNTCNTCN GAYNNNYTNYTNGARATGYTNGCNGARMGNYTNGGN---------------TCNGANGAY NNNYTNATHAANNNNATGAARGARYTNCCNGCNAGYGCNTTYNNNYTNNNNNNNNNNNNN NNNNNNNNNNNNAARTTYACNNNNATHGAYGGNGARATNTTYCCNNNNNNNTTYNNNNNN ATGNNNNNNGAYGARGANTAYYTNNNNMGNGTNGGNTTYTAYGANMGNGAYTAYYTNGTN NNNNNNACNNNNAAYGARGGNGCNNNNNNNNNNNNNGGNNNNTTYGCNATHGARNNNGAY NNNAARNNNNNNNNNNNNNNNNNNNNNCCNNNNGANGTNNNNCARAANNNNYTNNNNTGG TAYNNNGARGAYGGNCAYCAYAGYNNNNNNCCNGARAANGANNNNNNNNNNGAYNNNNNN NNNNNNYTNCCNNNNYTNAARTTYYTNGANNNNNNNNNNNNNMGNGGNAARNNNNNNYTN YTNNNNTTYGAYCAYNNNCCNGAYTAYNNNCCNTCNNNNYTNNNNGGNACNCCNCAYNNN NNNGAYYTNNNNTAYYTNTTYGAYNNNNNNCCNAAYNNNYTNNNNNNNNNNTAYTAYNNN ATGCANACNGAYNNNNNNTTYNNNGARGARGANAARNNNYTNAARTCNNNNNNNATHAAR YTNATHGTNGAYTTYATHNNNNNNGGNGAYCCNAAYNNNNNNNNNNNNTCNNNNYTNNNN CARAARTGGCCNNNNTAYGAYNNNACNAAYNNNNNNTAYYTNNNNTTYAANTCNNNNNNN CARGTNNNNCARCAYNNNNNNNNNNNNMGNNNNCARNNNNNNGARGARNNNNNNCCNMGN TGGYTNAARGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CARTAYATHAAYTAYAGYATHAAYAAYAARACNGARCAYTGY ACNCAYGGNTGGGTNTAYCARTGGGAYGAYTCNCCNTCNTCNTCNATHGTNTCNGARTTY AAYYTNGTNTGYGGNGAYGAYTAYYTNAAYGARYTNTCNACNACNATGTAYATGGTNGGN GCNACNTGYGGNGTNGTNTTYYTNGCNCCNYTNGCNGARMGNTAYGGNGCNAARAGYGTN ATGYTNATHTGYYTNTGGYTNCARATHATHGTNGGNGTNGCNGTNGCNTGGCCNGGNTAY ATH--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GARYTNTTYMGNGGNTTYYTNYTNTCN GARCAYAGYGAYGARAAYATHGARTTYTGGATHGCNTGYGARAAYTAYAARTCNACNAAR TCNCAYAARCARYTNCCNGCNYTNGCNAAYAARATHTAYAAYGAYTAYGTNGCNGTNYTN TCNAARMGNGARATHAAYYTNGAYTCNAARACNMGNGCNTCNACNCARGARGGNGTNGCN AAYCCNACNMGNCARACNTTYGAYGARGCNCARAARMGNGTNCARGCNYTNATGGARAAR GAYTCNTAYATGCAYTCNYTNAARYTNMGNAAYGAYGAYGTNATHYTNGCNGGNTAYATG AARTCNGGNACNCAYTGGGTNTGGGARATHATGMGNATGYTNTTYGCNGGNACNACNGAY ATHCCNGTNGARGARAARGAYAAYGCNATGATHGARCARATGGARCARGAYCAYYTNGAY TCNYTNCCNTCNCCNMGNATHYTNAAYTCNCAYGCNCCNTTYAARCAYYTNCCNGGNGAR ATH--------------------------------------------------------- ---ATGCAYCCNTAYTAYTAYGTNCARTAYGTNCCNATHTCNYTNAARCARGAYYTNGAR ATGAARGTNAAYTGGGCNGCNTCNCCNAGYACNGCNCCNAARCARGAYACNAGYAARCAY TTYCAYGTNTTYGTNGGNGAYYTNAGYTCNGAYATHGARCARCAYCARYTNMGNGAYGCN TTYTCNAGYTTYGGNGARATHTCNGAYTGYAARATHATHMGNGAYCCNGCNACNATGAAR TCNMGNGGNTAYGGNTTYGTNTCNTTYGTNAAYAARCARGARGCNGARACNGCNATHAGY GGNATGAAYAAYCARTGGYTNGGNACNMGNGTNATHMGNACNAAYTGGGCNACNMGNAAR CCNYTNGCNCCNGTNGCNAARGARAAYGCNAARCCNYTNATHTAYGARGARGTNTTYAAY CARTCNAGYTCNACNAAYTGYACNGTNTAYTGYGGNGGNGTNACNAAYGGNYTNACNGAR GARYTNATGMGNAARACNTTYTCNCARTAYGGNACNATHCARGARGTNMGNGTNTTYAAR GAYAARGGNTAYGCNTTYATHMGNTTYAGYAGYAARGARGCNGCNACNCARGCNATHTGY GGNGTNCAYGGNAAYTCNGTNAAYGARCARCCNGTNAARTGYTCNTGGGGNAARGARTCN AAYGARTCNAGYCARGGNGGNCARCARTCNTCNAAYCCNCCNGTNGTNATGYTNCCNTCN CARCARCARCARCCNATHGCNGCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GGNTAYACNGAR ACNGCNGTNYTNGARCARGARGGNGAYATHCCNGCNTAYGGNCCNGCNAARYTNCCNAAY TAYATHGARGCNACNACNYTNCCNTCNTAYGARGARGCNGARMGNAAYAARGARGARGAR GARACNAAYGCNGCNGCNTCNCAYACNGAYTGYGARAGYGGNMGNYTNGCNGGNGTNGAY GGNATHAGYGARGTNACNATHGGNACNGAYGGNATGTTYATHTGYACNTTYTTYATHTCN TTYYTNTTYAAYTGGYTNGGNTTYYTNYTNTCNYTNTGYYTNTCNAAYACNATHGCNGGN MGNTGYGGNGCNYTNTCNGGNYTNGGNYTNTCNATHGTNAARTGGGTNGTNATHGCNAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYATHGARACNGTNTAYCAYGTNTCNAGYTGGGGNTTYAARGCNGTNGCNGTN GAYYTNCCNGGNTAYGGNAARTGYGTNAARGARAAYAARGTNACNAAYTGYGCNGARTTY ATGACNTCNYTNATHTCNGCNYTNGGNYTNTCNCARTTYGTNATHGTNTCNCCNTCNATG AGYGGNMGNTTYTCNYTNCCNTAYYTNTTYGARGAYGGNAAYACNAGYACNCARAARGCN ATGGGNTAYGTNCCNGTNGCNCCNATHGARACNGARCAYTAYGTNGCNGARTAYAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATHAGYYTNGGNATHYTNATGYTNYTNACNATHMGNMGNYTNTAYTGYTTYYTNMGN TAYMGNTCNATHATHAAYAGYYTNCCNGGNGARACNTCNTTYAGYYTNYTNYTNGGNAAY YTNCAYAARCAYCCNGGNCCNAAYGARGARGGNYTNTCNTAYGAYTCNGGNYTNATGAAR AARTGYMGNACNTTYCAYMGNGTNTGGGCNGGNCCNGTNAAYGCNGTNGTNATGYTNTAY CAYCCNGAYTCNATHMGNCCNATHGTNAARTCNCARGTNCCNAARTCNMGNMGNAARTAY YTNGCNTCNCCNTAYGAYATGGGNATHAARTGGYTNGGNGARGGNATHYTNYTNACNAAY GGNAAYMGNTGGAAYMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARAAYTCNGGNTAYYTNTCN GARATGGARGTNTCNAAYMGNMGNYTNACNGARAARATHAARAARYTNAARGARGAYGGN GARTTYCAYGARGARYTNCARGARGARYTNGARAAYAARGTNAARGCNCARGGNAARGAY YTNGARGCNAARMGNGCNGARATHATGAARYTNAARGARGGNACNGCNYTNYTNGARATG MGNYTNGCNGARGTNCAYGARMGNAAYCARAAYATGAAYTCNGARGTNCAYGCNTGGAAR AARAARTAYTGYYTNGCNMGNGAYACNGCNGAYMGNYTNGARGARGARYTNACNAARMGN GARGARMGNGTNCARGTNYTNACNCARCARYTNCAYGARGCNGTNCARCARACNYTNGCN CARCARAARGCNYTNYTNTCNTGYTCNGARMGNGARAARTGYAARGARGARATHGTNAGY TCNYTNMGNAARCARCARAAYMGNACNATGAARGARYTNACNAGYATHMGNGARYTNTAY GAYAARCARACNMGNGAYATGCCNYTNTAYCAYYTNAGYGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TGG GCNAAYTCNTAYMGNTGYTTYGARTGYTGYAARGGNTGYTGYTAYAARATHATGACNYTN TTYTGYGGNYTNTTYATHGCNATGTTYTGGGGNTGYGARTTYGCNGTNATHACNTTYGCN CAYGTNTGGTAYGTNACNCCNTGYYTNMGNTGYTAYATGATHAAYTGYGGNTGYYTNCAR AARTTYTAYGGNACNTGYYTNAGYTGYTAYATHCARCCN--------------------- ---------------------------------CARMGNCARMGNGARGARGARYTNMGN ACNCARTCNYTNAAYAAYGARACNCARYTNGCNAAYAARCARACNGAYGTNGAYMGNYTN GARCAYATGYTNGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNACNGGNCAYGCNGCNGAYATHYTN AARCARAARGGNYTNAARGGNTAYGTNGTNAARAARTCNAGYGCNAARCCNGAYGARGAR ATHYTNYTNACNGCNGARGARGARAARGTNGAYTAYATHGTNATGGGNACNMGNGAYYTN GGNAGYYTNAARMGNGCNYTNATHGGNAGYGTNAGYACNGARGTNGTNMGNCAYGCNAAR TGYCCNGTNACNGTNGTNAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARMGNMGNATHMGNTTYTCN GGNACNMGNTAYAARGCNYTNAAYMGNMGNYTNGARMGNTTYYTNAAYAARCARAARMGN TTYCCNGAYTAYCAYGAYGTNCAYMGNGTNGTNAAYYTNACNAAYAARAARTAYGGNYTN AGYATGAGYGCNAAYAARGTNAGYGAYGTNTCNMGNGARGCNTTYATHGAYATHGGNGAR ATGYTNCARACNMGNMGNCAYGARGAYTTYATHGCNACNTTYGGNACNAAYCARACNGAY TTYGGNCCNGAYCCNGCNATGGCNGAYGCNCAYYTNMGNMGNAARYTNGAYGCNAAYMGN AARMGNCARCARGTNAARCCNTCNGGNAGYYTNGARATHATHGAYGGNGAYGAYGGNACN ACN---------TTYTTYAAYYTNGARMGNTCNCCNTCNGARGCNTCNTCNMGNCCNTGG TCNMGNGCNAGYGTNGGNTCNGTNCCNCCNMGNAAYGAYTCNTCNYTNAGYMGNMGNGTN YTNACNCCNACNAARCARGTNTCNYTNCARGCNGTNAARMGNAARGARGARAGYTCNGAY CCNATHYTNGARGAYGTNGAYTTYAARGAYYTNAAYATHGGNACNAAYMGNMGNAARGTN TGGGGNAGYYTNGARGARGARGAYTTYGAYGGNGGNCAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GCNAAYMGNYTNATHTGGATHGAYYTNGARATGACNGGNYTN AAYGTNGARAAYGAYMGNATHATHGARATHGCNTGYYTNATHACNGARGARGAYYTNACN CCNGTNGCNGARGGNCCNAAYYTNATHATHCAYCARAGYGAYGAYTTYYTNAAYMGNATG GAYGARTGGTGYGTNMGNACNCAYGGNGARTCNGGNYTNACNAAYGCNGTNMGNAAYTCN AARATGAGYACNGCNGARGCNGARMGNAARGTNYTNGARTTYGTNCARAARTAYACNCCN CAYGGNAARTGYCCNYTNGCNGGNAAYTCNGTNAGYATGGAYAARCARTTYATHCARCAR TAYATGCCNCARYTNGCNGAYCAYYTNCAYTAYMGNATHGTNGAYGTNAGYACNATHAAR GARYTNTGYMGNMGNTGG------------TAYCCNTCNGTNYTNTCN------------ ---------TCNGCNCCNAARAARGCNYTNTCNCAYMGNGCNYTNACNGAYATHAARGAR AGYATHGARGARYTNMGNTAYTAYAARACNAAYATHTTYAARGTNGAYMGNAARGAYTCN TAYGGNACNAAYCARTTYAAYTGYCAYYTNGGNACNACNTAYAARATHYTNGTNGTNCCN AAYGARGCNGCNACNTTYYTNTCNTGYGGNGAYGAYGGNACNGTNMGNTTYTTYGAYYTN MGNGTNAARACNAGYTGYTCNAARTTYAAYTGYGARGAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------MGNGARTGGATHGCNCCNATGACNTGYATGTAYTAYACNCAR AARYTNYTNCARGARMGNGTNAGYAAYCCNGCNGTNTCNAARATHYTNCAYGAYACN--- CARGTNTAYATGACNCCNGTNYTNAAYMGNGAYGGNTAYGARTAYTCNTGGGARACNAAY ------MGNATGTGGMGNAARAAYMGNCARCCNAAYGCNTCNTCNTAYATHGGNACNGAY YTNAAYMGNAAYTGGGAYTCNGCNTGGGGNGGNTGYGGNGCNTCNACNGCNCCNTCNTCN GAYACNTAYMGNGGNACNGCNGCNTTYTCNGGNACNGARGCNGCNGTNGTNMGNGAYTTY TTYGARAARYTNAAYAARCAYATHYTNGGNGGNCAYGAYTTYCAYTCNTAYGGNAAYYTN YTNYTNMGNCCNTAYGGNTGGACN---GCNCARCCNTCNAAYAAYGAYATGATHGARGGN GCNMGN---GGNGCNAARATGGTNGARGCNATHMGNCARCARTCNGGNCARGTNTAYCAR AAYATHAARGCNTAYAAYYTN------TAYTGYTGYTCNGGNYTNGCNGTNGAYTGGATH GCNGARCARACNACNGARTAYAGYGGNTTYACNTTYGARYTNMGN--------------- GGNTCNAGYTTYGTNYTNCCNCCNGAYCARATHGTNCCNTCNGGNGARGARATHTAY--- ------------------CCNCARCAYGARACNAGYGARMGNYTNTGYMGNGCNTGGATH GTNCCNACNCCNAGYCARAGYAARGARCARGTNTTYTTYATHYTNTTYYTNTCNTTYGTN TAYYTNTGYYTNTTYYTNGGNAGYGTNTCNGGNGGNAGYGTNTGYTAYCARGTNAGYMGN MGNATGGGNGCNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AAYGGNAGYCAYGAYYTN ATHGARGCNTGYAARGTNGCNGCNCCNTCNATHGGNAARGAYTGGAARAARGTNTAYYTN TGYYTNCCNTTYGAYCCNCCNMGNGARATGGCNAARMGNGARCAYGAYGTNACNGTNYTN GAYTTYATHGCNGGNMGNAAYGAYGTNACNCAYGCNGARCARGCNYTNAARAGYYTNGAR AARTGGMGNACNTTYCAYMGNAARGGNGAYGTNATGGAYYTNATHMGNGCNYTNCARAAY GTNAARAARMGNMGNATHGCNGGNGARYTNCARAAYMGNTTYGTNTAYTCNGTNAARTAY GGNGCNGTNTTYATHATHTTYYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TAYGCNGGNATHYTNTAYGGNATHACNAAYTTYGTNTCNACNATHCCNGGNATHYTNGCN CCNATHGTNACNGGNGCNYTNACNCCNAAYAARACNTCNGARGARTGGMGNAAYGTNTTY TAYGTNTGYGGNGCNTTYACNYTNGTNGGNGCNYTNATHTTY------------------ ------------------ATGTTYMGNMGNGARAAYATHMGNAARAAYTTYYTNMGNGTN AARCARAAYATHGAYCARAAYYTNGGNMGNGCNGARAARTCNGARGTNYTNTCNGGNGGN CARCARGARTAYGARAARMGNGTNGAYGTNGTNAARCAYTCNYTNCCNAAYGTNATHAAR AARGCNGGNGTNYTNYTNCARGCNCCNGGNACNGAYGTNGAYAARMGNGTNAARAARYTN CCNCARAAYGGNYTNGGNYTNGCNYTNYTNGARTCNGCNCARAGYYTNGGNTCNGARACN YTNYTNGGNAARGTNTTYCARACNAGYGGNGARAGYCARYTNAAYCARGCNMGNGARGAR GTNCAYTAYGARAGYATGGTNGARCARGAYTTYGTNGCNCCNYTNCARCAYATHGTNGAY GTNGAYATHCCNAAYATHYTNMGNATHAARAARAAYYTNAGYAARTCNACNYTNGAYATG GAYTCNGCNAARAAYMGNTTYCAYCARGCNGTNMGNCARTCNCARGTNCCNGGNGTNAAY ATGGCNAAYGCNGCNACNAARGCNGAYACNATHMGNGARGARTAYGARGAYGCNACNTCN AARGTNGARAAYATHAARGAYAAYYTNTCNATHGARYTNCAYAAYTTYGCNTCNAARGAR AGYGARCAYGCNCARATHYTNGTNATGYTNYTNAARGCNCAR------------------ ------GARAARAARMGNGAYMGNGAYMGNCCNCCNTCNAARGTNGTNATHMGNMGNYTN CCNCCNACNYTNACNCCNGARGAYTTYYTNGARATHGTNTCNCCNYTNCCNGAYCAYGAY TTYTTYTAYTTYATHMGNGCNGAYATGAGYYTNGGNAARAAYGCNTTYACNMGNGCNTAY ATHAAYTTYYTNAARCCNGARGAYATHTTYATHTTYMGNGAYCARTTYGAYGGNTAYATH TTYGTNGAYTCNAARGGNGGNGARTTYCCNGCNGTNGTNGARTTYGCNCCNTTYYTNAAR GTNCCNAARAARAARCCNMGNAARATGGAYGCNAARAAYGGNATHATHGARCARGAYGCN GAYTAYAARAARTTYYTNGARATHYTNGCNAARCCNATHGARGCNCCNGTNGTNTCNYTN GAYGCNATHGTNGARGARGTNGARGCNAARGARCARAARYTNGCNAARTCNGGNAGYATH MGNACNGCNACNCCNYTNYTNGAYTAYYTNAARTGGMGNAARGARGARMGNAARATGAAY YTNGCNAARYTNAARGARGAYMGNMGNMGNGGNAGYGCNMGNGAYMGNGAYGTNGAYMGN AARMGNAAYMGNAARGAYYTNGAYGAY---------------------------CAYTGG TCNAARTCNGARMGNGAYMGNCARAARGAYMGNGAYMGNMGNAARGAYMGNGTNAARGAY AARYTNAARGARMGNGAYMGNAARMGNGARMGNGARMGNCCNYTNMGNMGNGGNGARMGN CCNAARGARGARMGNAGYGGNGGNGCNAARTCNTCNMGNGAYGGNGGNGARAARATGAAR ------GTNACNGTNYTNAARAAYACNGARMGNGARAAYCARCCNGTNGARMGNYTNCCN GAYTAYGGNGCNAARCCNGARAARGGNAARGARGTNGARGARAARGARMGNGARGCNMGN AGYGGNGARGGNMGNGGNGGNGTNGGNAARGGNGGNCAYGARAARTGGMGNMGNGARGGN GAYATGGARMGNCCNGGNGGNGGNGAYGAYTGGMGNGAYMGNGGNCAYTAYGARTCNGAY TAYGGNGGNGGNCAYTTYGAYYTNCCNAARGARATHGCNGGNACNTTYCARTCNTCNGGN ACNTGYGAYGARTCNACNTGGAARGTNGAYGTNATHTAYACNATHACNGCNTAYGTNACN GGNGCNAGYTCNGTNAARGCNATHCARCCNGTNGTNGTNTAYCARGCNAARGARAARGAY ATGCARGAYAGYCAYYTNGGNACNGCNGGNCAYACNAGYTTYCARATHCCNMGNTTYYTN AGYAAYCARGAYGTNCAYATHACNGTNAARYTNYTNCARAAYTTYGTNGARAGYGGNAAR AAYATHCARYTNMGNGTNGTNATHACNAAYCCNAGYAARGARAARGTNACNGGNGTNGCN GTNMGNGTNTCNMGNAAYYTNMGNYTNAAYTTYMGNGGNTCNAAR---YTNAARMGNAGY YTNGTNTCNGARTTYGTNGARAARGAYTGYGTNATHTCNCCNGAYGGNGAYTCNCAYATH GTNAAYACN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CARTGGACNGTNTTY TCNMGNGTNCARAAYTTYCCNTTYAARTTYTAYTGGAARAAYGCNMGNGTNTTYMGNTTY TAYATHTAYAGYTCNYTNGTNGTNATHCCNYTNTTYATGAARYTNACNAARGCNTCNGAY GCNAARACNYTNCARGCNGCNCARYTNGCNCAYGCNCARYTNCAYYTNGGNGGNGTNCCN GTNTTYYTNCCNCCNGGNCAYCCNCAYGCNGCNYTNMGNCAYGGNGCNCCNGTNCARACN YTNGTNTCNGTNGGNGGNAAYACNCCNGGNCCNGAYGAYGCNACNMGNATGGCNGCNCAR CCNTTYTCNYTNCARATGMGNTCNCCNGCNCCNGCNGGNACNCCNATHATHTTYGCNCCN MGNYTNCCNCCNCCNACNATGGTNTCNACNAGYCARCCNAGYATGAAYGGN---GCNCCN CCNCCNYTNGTNTCNCCNTCNGCNGAYACNGCNGGNYTNATGTAYAAYCCNTAYGCNGTN AAYGCN---GGNACNATGGGNGCNGCNATGCAYTCNGCNGTNGAYCCNTAYGGNYTNGGN GCNACNACNCCNCARGCNGGNGCNGTNCCNAARATGMGNMGNTCNYTNGAYGGNGTNMGN GGNCAYCCNTAYACNMGNGTNTCNYTNTCNATGGCNGAYACNYTNCARYTNYTNAARTGY GGNGTNMGNTTYTCNCCNCCNTCNYTNGTNYTNACNTAYAARGAYTGGAARTCNGGNAAR ATGMGNMGNMGNTGYATGCCNYTNMGNAAYTTYAAYAARAAYACNGGNGTNGAYMGNTTY GTNGAYGARYTNAARGTNAGYCCNMGNCAYGCNMGNTAYGTNMGNYTNYTNTGYCCNGCN CARYTNCARMGNYTNYTNACNATHGTNAARGAYAARYTNAGYGGNYTNAGYYTNGARGCN AGYATHGCNMGNAAYAAYGCNATGGAYAARYTNGAYCCNGAYGARAAYYTNAAYACNGTN GAYGARGARACNYTNAARMGNAARAARYTNCARATGGAYACNTCNTTYGARMGNAAYMGN AARAARCCNGGNGAYCCNGAYTTYGTNTAYAAYGTNGARGTNGAYTTYGARGCNGCNGTN GTNGARACNAGYGGNTGGGAYTCNGGNGCNTCNGAYYTNGAYTTY >clavigera ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GAYCCNYTNTAYAGYGGNGCNCAYGARMGNGAYCARGARCAYATHGARCAYAGYGCNYTN CAYGGNTTYCARTCNGTNTCNGGNGGNACNTCNCARGGNGCNCCNAAYAAYAARCARCCN AARAGYGAYAARCARYTNCCNGCNTAYTGYAAYCCNCCNAAYCCNTGYCCNYTNGGNAAR ACNGCNAARGAYAAYTGYGTNGARGARTTYGARAAYAGYGCNGAYAAYAAYAARAARYTN YTNAGYGARCARGARTGYCCNTGYGAYACNGARCAYATGTTYAGYTGYCCNGCNGGNAGY GARACNGTNTCNTCNAARGGNCAR---AGYGGNAGYCARGCNYTNAAYAARGTNATHGAY CARYTNTCNAARATGGARCAYAGYGTNGGNACNATGGARAGYCARCCNGCNYTNTCN--- TCNMGNAARMGNYTNACNGTNGTNGCNAARAARTCNCCNTAYATHATHCAYAARMGNTCN GARCARATHGTNMGN---AAYCCNTAYTTYAARGGNCCNMGNATGGAYATHGCNGCNAAR AARAAYCAYAARYTNGCNCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNGTNCARAGYYTNTCNGGNGCNAGYATHGARGAY AARTAYGARCCNATGGTNGCNTTYATHTGYGGNMGNCCNGCNATGCAYMGNGGNGTNAAY AAYTGGGTNCCNGAYAARACNAARGARTGYCCNGAYACNYTNGARGAYGTNYTNGCNTAY TGYAARAARGTNTAYCCNGAYCAYAAYATHACNAAYGTNGTNGARGCNTCNTAYYTNGTN GAYATHCCNAAYTGGCCNATGGGNACNGCNAAYMGNACNCAYCCNCAYCAYGTNMGNCCN TTYMGNTGYYTNGTNGGNGGNTTYCARTCNGAYGCNYTNYTNGTNCCNCARCAYTGYGAR TTYGAYCAYMGNCAYGAYATHGCNAARTGYGARGGNTTYTCNCAYTGGAAYGARGTNGCN GARGARGCNTGYGTNAARAARGGNATGCAYYTNGARTCNYTNGGNATGYTNYTNAAYTGY AAR---YTNGGNCAYTTYAAYGGNGTNGARTAYGTNTGYTGYCCNAAYGARACNGAYACN MGNATHCAY------CCN---GCNACNGARGAYGAYAAYCCNGAYCARTGGGAYAGYTCN TCNAARGARGARGARGARAARGAYCARGARGARCARGAYAARGARAGY------------ ------GCNGARGCNGARGARGAYGAYAAYGAYAGYGCNAGYATHAGYGCNAGY------ ------------------CARGARCARGARGARAARGTNGCNGAYYTNTAYGARGCNTAY YTNMGNGAYAARGAYTTYCCNACNGCNTAYAAYAAYGARCAYAARAARTTYYTNGCNGCN AARGGNMGNATGAARAARAAYCARAARCAYAARGTNGCNAARYTNYTNCARGAYTGGCAR AARGCNMGNGARCAYGTNAGYGARGTNMGNAARACNGAYCCNAARACNGCNGAYAAYATG AAYAARGARATHGCNGAYMGNTTYCARAARYTNTAYGCNTCNTTYGARCARGARGAYGCN GCNGARAARCARCARYTNATHGCNYTNCAYCARCARCAYATHCARGCNACNYTNAAYGAR AARAARMGNGARGCNATGGAYAARTAYATGGARGCNYTNGARAAYGGNGARACNGAYAAR ATHGCNMGNTAYYTNMGNAAYTAYATHAARACNGARGARAARGAYMGNATGCAYACNGTN AAYCAYTTYGARCAYATHAARTAYTCNTCNCCNCAYGARGCNGTNMGNATHMGNCCNCAY ATHATHAAYCAYYTNAARYTNTCNGARCARMGNATHGAYCARGCNYTNGARATGYTNACN MGNTTYCCNAGYATHGARACNAARATHMGNCCNGARATHGARGARTTYATGMGNMGNTTY AAYGCNATHGCNACNAGYATHAARAAYGTNGTNYTNCCNGTNCCNACNATH--------- ---------------------------GCNCCNYTNMGNGAYTCNAAYTCNGARAAYACN GAYGAYGAYATHAGYATHGAYGARGARGARGAYGAYGAYGTNTCNAGYGARAAYGTNGAY AARGAY---------------------------------------GGN------------ ---------------------------GAYGAYATHGCNGARGAYGARCAYGAYTAYGAR MGNAARGGNGTNTAYGTNGCNCAYGCNYTNTCNGGNACNCAYTCNGTNAAYCARGGNYTN GAYTCNAGYGGNGCNGTNTCNTCNCARATHGGNAGYACNATHGGNATHGCNYTNGGNAGY GTNAGYGTNTTYGTNATHATHGTNGTNGCNATHATHATGATHMGNMGNAAYCAYCCNMGN CCNACNGTNGCNCAYGGNTAYGTNGARGTNGAYCCNTCNGCNTCNCCNGARGARMGNCAY YTNACNAAYATGCARATGAAYGGNTAYGARAAYCCNACNTAYAARTAYTTYGARTCNGAY ACNAARGAYGARYTNTAYMGNMGNATHATHGTNGARGTNAARGGNCAYGAYCARTCNGTN YTNAAYAGYTAYACNAARTTYACNACNATGGCNGCNGARYTNYTNGGNGTNAAYATHGCN AGYATHATGGARCCNCCNMGNGTNATHGARMGNATHAGYYTNYTNAARTCNGTNTTYGTN CAYAARAARCAYATGCAYCARTAYGARACNMGNACNCAYTAYMGNGTNTTYGARYTNAAR CAYYTNACNGGNTCNACNGCNAGYACNTTYYTNGARTAYATHCARMGNAAYYTNCCNGAR GGNATHGCNATGAARGTNACNAARCAYCARYTNCAYYTNTTYCCNGAYCAYYTNAARCCN CCN---------------------------------GAYTAYTTYAAYGTNATGYTNGGN TCNCARYTNYTNTAYAARTTYGARMGNCCNCARTAYGGNGARGTNYTNGCNGARTAYCCN GAYAARCCNATGTCNTCNATHTAYGGNGCNACNCAYTTYYTNMGNYTNTTYGTNMGNYTN GGNGCNATGYTNGCNTTYACNTCNYTNGAYGARMGNACNGTNCAYATHYTNYTNAAYCAY ATHCAYGAYTTYYTNAARTAYYTNTCNAARAAYGGNGCNAGYYTNTTYAARACNTCNAAY TAYGARATHGCNACNCCNGAYTAYCAYMGNAARGCNATHATGYTNYTNGAYMGNYTNYTN GARAAYTAYCAYAARTAYTCNMGNCCNGTNATHAAYGCNTCNYTNTCNGTNACNGTNAAR TTYGGNYTNACNYTNGTNCARATHTCNGAYATGGAYGARGTNAAYCARGTNYTNACNYTN AAYGTNTGGYTNGARCARGARTGGGTNGAYGARMGNYTNACNTGGGAYCCNAARGAYTAY AAYAAYYTNAAYATHYTNMGNATHCCNTGYGARAARYTNTGGYTNCCNGAYATHGTNYTN TAYAAYAGYGCNGAYGAYTTYACNAAYGGNTAYATGAAYAGYAARGCNATGGTNMGNTCN AAYGGNACNGTNTTYTGGCCNCCNCCNGCNAARTTYMGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGGARACNAARCARMGNTGGATHCCNYTNGAR TCNAAYCCNACNGTNYTNAAYAARTAYGTNCAYAAYYTNGGNATGGARGARACNTGGAAY TTYGTNGAYGTNTAYGGNYTNGAYCCNGARYTNYTNGCNATHGTNCCNCARCCNGTNGCN GCNGTNGTNYTNYTNTTYCCNGAYCCNAARTCNGCNAAY------GARAARCCNYTNGGN GARGTNCARGCNGARTAYGCNCCNGAYYTNTAYTAYACNAARCARACNATHGGNAAYGCN TGYGGNACNGTNGCNATHGTNCAYGCNYTNGCNAAYAAYCARGAYAARATH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNYTNMGNTTYGCNAARAARCARGAYATHYTNGGNCARATHAARGTN GCNATGGARATGCAYAARMGNTAYCCNGAYTCNTTYYTNGGNTAYGAYYTNGTNGGNCAR GARGAYCCNTAYAAYCCNYTNYTNTAYTAYATHGAYGAYYTNYTNTAYCCNAGYCARCAR AAYCCNCCNTAYAAYYTNCCNTAYTTYTTYCAYGCNGGNGARACNAAYTGGCARGAYTCN GCNGTNGAYYTNAAYYTNGCNGAYGCNYTNYTNYTNAAYACNACNMGNATHGGNCAYGGN TAYGCNTTYAGYAARCAYCCNGTNTTYGCNAARATGGCNAARGAYAARGGNGTNGCNGTN GARGTNAAYCCNATHTCNAAYCARYTNYTNAARYTNGTNACNGAYYTNMGNAAYCAYGCN GCNGTNCCNYTNATGACNGAYGGNTTYCCNGTNGTNATHAGYTCNGAYGAYCCNACNGTN TGGGARGCNGCNCCNATGTCNCAYGAYATHTTYYTNGCNTTYATGAAYATGTGYGGNGAR GAYGARGGNYTNGCNTTYYTNAARCARYTNGCNATHAAYTCNATHCARTAYAGYGCNATG AGYAAYACNGARAARACNCAYACNATGACNMGNTTYAAYATHAARTGGGAYAARTTYATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------MGNTCNYTNGCNATGYTNMGNYTNGGNAARMGNCCNATGAAYATGYTNMGN YTNGGNAARMGNGARGGN------------------------------------------ YTNGAYTCNTTYGARGAYGAYGAYGTNGARAGYTCNGTNCCNCARATGCARTCNAGYAAR AARAAYYTNAAYATGYTNMGNYTNGGNAARMGN---------ATHTCNGARGAYGCNAAR MGNAAYYTNAAYATGYTNMGNYTNGGNAARMGNCARATGAAYATGYTNMGNYTNGGNAAR MGNCARYTNAAYATGYTNMGNYTNGGNAARMGNGGNYTNAAYATGYTNMGNYTNGGNAAR MGNGGN------------------------------------------------------ ---------GGNGAYGAYGAYGTNGARAARMGNAAYYTNAAYATGYTNMGNYTNGGNAAR MGNGARGAY------GTNGARAARMGNAAYYTNAAYATGYTNMGNYTNGGNAARMGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYGTNYTNTCNGCNAAYYTNCAYGGNGGN GAYYTNGTNGCNAAYTAYCCNTAYGAYGARACNMGNTCNGGNAARATGCAYGARTAYACN GCNTGYCCNGAYGAYCAYGCNTTYGTNTAYYTNGCNMGNTCNTAYGCNTAYTTYCAYAGY TCNATGTCNGAYCCNGAYMGNATHCCNTGYGAYAARGGNGGNGARAGYAARCCNATHACN AAYGGNGGNCARTGGTAYTCNGTNCCNGGNGGNATGCARGAYTAYAAYTAYYTNAAYACN AAYTGYTTYGARATHACNYTNGARYTNGGNTGYGARAARTTYCCNCCNGCNTCNGARYTN GARCARTAYTGGMGNGAYAAYGCNCARGCNYTNTTYAAYTAYATHYTNCARAGYCAYACN GGNGTNAARGGNTTYGCNGCNTCNGCNGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNTAYATGATGACNAARYTNYTNTAYTTYGCNAAYGTN ATHTGYCARTTYGTNYTNYTNTCNGCNTTYYTNGAYYTNAAYTAYTGGAAYTTYGGNTTY AAYGCNATGTCNGTNYTNAGYAARACNGGNMGNTGGCARGAYCAYTAYCAYTTYCCNMGN ATHGGNYTNTGYGAYTAYAARATHMGNCARYTNCARAAYGTNCARACNCAYAGYGTNCAR TGYGTNYTNTCNATHAAYATGTTYYTNGARAARATGTAYYTNACNYTNTGGTTYTGGYTN ATGATGYTNYTNGTNTTYAAYTCNATHAAYYTNYTNCARTGGATHTAYMGNGGNGTNATG CCNAAYMGNGGNGARGCNTTYATGAARAARTAYYTNYTNYTNYTNGGNGTNGAYTCNAAR MGNGARAARAARYTNTTYAARAARTTYGTNCAYGGNTAYYTNMGNACNGAYGGNATGTTY ATGYTNMGNATHGTNGCNTCNAAYACNAGYGARATHYTNACNTGYGAYYTNATHAARCAR YTNTGGAAYATHTTYMGNACNAARTAYCAYGAYGAYAARGARTCNCCNAARGAYCCNAAY GGNGGNCCNCCNGCNTAYACNAAYGGNCCNYTNGTNTCNGARAAYGAYGAYGAYYTNCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNGAYCCNATHATHCCNATGGTNAARCARGAYTCN CCNGTNMGNATHAAYAGYAAYATHGCNYTNATHAAYGTNAAYGAYGTNGAYGARGARGAY AAYYTNGTNGAYATHAARACNGTNGGNGARATHTCNTGGGAYACNGGNATHACNTGGGAY CCNAARGAYTTYGGNGGNGCNGAYCAYATHCARYTNCCNATHCAYTAYTTYTGGATGCCN ATHTTYGGNTCNTTYGAYGTN---TAYGGNCCNATGCARACNYTNGARACNAAYATHATH ATHYTNCAYAGYAAYGGNACNYTNTTYTGGTTYCCNGTNACNMGNTAYTCNATHYTNTGY GAYGTNTCNAGYATHCAYACN------GGNGCNACNTGYAARGTNTCNTTYTCNAGYAAY GAYATHGTNGCNTTYGGNGAYGCNAARAARACN------------GTNGAYYTNTCNGGN TAYAAYCCNGCNTCNAARTAYGARGTNTCNGAYGCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYYTNMGNYTNCCNAARAAYGCNYTNCCNGAR AAYTAYGCNATHTTYYTNCAYCCNAAYATHCCNGCNTCNAGYTTYAARGGNMGNGTNACN ATGGCNYTNMGNATHGTNCARMGNACNGAYTTYATHGTNTTYCAYTCNACNCARATHACN YTNACNCCNGTNCARCCNCCNTTYACNAAYAAYAAYYTNACNAARGTNAAYGTNGTNAAR GARYTNGAYTAYCCNACNAAYCARCARCAYTAYGTNCARYTNGAYMGNATGYTNGAYGCN GGNACNGTNATHTAYYTNCAYGTNGGNTTYAAYGGNTCNYTNYTNACNAARATGAAYGGN TTYTAYAARAGYGCNTAYACNGTNAAYGGNCARCARMGNTTYATGGCNAGYACNCARTTY GARTCNACNTCNGCNMGNGAYGCNTTYCCNTGYATGGAYGARCCNGCNYTNAARGCNGCN TTYAARATGAGYATHGTNMGNGAYGCNCARCAYATHACNYTNTTYAAYACNCCNYTNGTN AAY---ACNGTNCCNTTYAAYGGNAGYACNAGYGGNGAYTTYGARMGNACNGTNMGNATG AGYACNTAYYTNYTNGCNTTYGTNGTNTGYGAYTTYAARCAYYTNGARAARTCNACNAAR GAYGGNGTNATGGTNMGNATGTTYGCNCCNGARGAYAARATHTAYATGGGNCAYTTYGCN YTNGAYGCNGCNGTNAAYATHATHGARTTYTAYAAYCAYTTYTTYGGNGARCCNTAYCCN YTNCCNAARCARGAYYTNATHGCNATHCCNAAYTTYGCNGCNGGNGCNATGGARAAYTGG GGNYTNATHACNTAYMGNGAYGTNTCNGTNYTNTAYGAYCCNAARGTNTCNACNGCNTCN ACNMGNCARTAYGTNGCNYTNGTNGTNGCNCAYGARYTNGCNCAYCARTGGTTYGGNAAY YTNGTNACNATGAARTGGTGGAAYGAYYTNTGGYTNAAYGARGGNTTYGCNACNTAYGTN GARCAYATHGGNGCNGAYGTNGTNGAYAARGAYTTYCAYATG---AAYGARCARTTYATG GTNTCNYTNAGYGAYGCNYTNMGNYTNGAYAGYYTNGCNTCNTCNCAYCCNATHGARGTN GARGTNMGNAAYCCNGTNGARATHGARGCNGCNTTYGAYCARATHTCNTAYGAYAARGGN TCNTGYYTNATHMGNATGYTNGARAAYATGGTNGGNGCNGAYAAYTTYAARCARGGNYTN TCNTAYTAYYTNMGNGARTAYAARTAYGGNAAYGCNGARACNAARGAYYTNTGGGAYGCN TTYAGYAARGCNYTNACNGAYGGNYTNGAYGTNACNAARGTNATGGAYACNTGGACNAAR CARATGGGNTAYCCNGTNATHAARYTNACNMGNCAYAARGGNAARYTNYTNATGTCNCAR ACNMGNTTYYTNYTNAAYAARGAYGTNAGYGAYACNGARGTNGCNACNTCNCCNTTYGGN TAYAARTGGAAYATHCCNTTYACNTAYATGACNTCNGAYGAYCCNAAYGGNTCNCARYTN GTNTGGATGAARYTNTCNGARGARGTNCAYYTNCARGGNTCNCCNGCN---TGGGTNAAR GGNAAYGCNAARAGYAARGGNTTYTAYMGNGTNAAYTAYGAYGCNYTNGGNTGGMGNGCN ATHATHCARCARYTNAARGARAAYCAYAARGTNTTYTCNGTNGARGAYMGNGCNGGNYTN GTNGAYGAYGTNTTYACNYTNGCNTGGGGNGGNGARATHGAYTAYCCNATGGCNYTNGAR YTNTGYYTNTAYYTNGTNAARGARGAYAGYTAYTAYGTNTGGAGYAAYGCNYTNTGGCAY YTNMGNTCNGTNGCNAAYYTNATHTAYYTNCAYCARTCNTAYGAYGAYYTNAARGAYYTN ATHCARCAYYTNACNGGNCCNYTNATHGAYGCNYTNGGNTGGGAYGAYGTNGGNAGYCAY YTNGAYAARATHATGMGNTCNYTNATGATGGCNAAYGCNGTNCAYTTYGAYTAYATGCCN GCNGTNAARGTNGCNMGNTCNAARTTYGARCARTGGAARTCNGAYGARTCNAGYYTNAAY AAYAAYYTNMGNTCNATHATHTAYACNGCNGGNGTNMGNTAYGGNGTNAARGARGAYTGG GAYATGGTNTTYCARMGNTAYCAYACNTCNAAYGTNCCNTCNGARAARATHACNYTNYTN GARTCNYTNGGNGCNTCNMGNGAYCCNMGNGTNYTNMGNATHYTNYTNGARTAYAGYYTN GAYACNAGYAARGTNAARTCNCARGAYACNGCNMGNGTNATHAGYTCNGTNGCNCAYAAY CCNACNGGNTCNYTNTTYGCNTGGMGNTTYTTYMGNCARAAYTGGGAYACNTTYTAYAAR MGNTAYAGYCAYGGNTCNTTYATGYTNAGYAAYYTNATHMGNTCNGTNGTNAAYAAYTTY TCNACNCARTTYGAYYTNGAYGARGTNACNGCNTTYTAYGARGAYAARGAYGTNGGNAGY GCNAARATGGGNYTNGARCARGCNAARGARATHATHAGYTCNCAYATHGCNTGGGARAAR AAYCAYYTNGAYATHGTNAGYAARTGGYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TTYGARTCNGARGTNYTNTTYATHATGAAYMGNYTNACNCCNACNAAYTTY GARAARYTNGCNAAYGARATGAARMGNYTNAAYATHGAYACNTAYGAYGAYYTNGTNGAR GTNGTNMGNATHTTYTTYGARAARGTNACNYTNGARACNAARTTYGTNGARGCNTAYGCN AARYTNTTYAARATHATGTCNGCNTAYMGNGTNCCNCCNCCN------CCNGGNGTNAAR GARAAYCARGCNACNTTYYTNGTNGTNATGYTNACNAARTGYCARCAYGARTTYGARGCN GAYAARAGYATHATHTTYGARAAYCCNGARGARAARAARAARAARATHYTNGCNGARAAY CCNGAYACNCCN---GARMGNGCNGGNATGATHGARAAYACNYTNTAYCARATGAARYTN AARMGNATGAARTTYTAYGGNAAYATHMGNTTYATHGGNGARYTNTTYAARYTNGGNATG YTNACNGARAAYATHATGCAYGAYTGYATHTTYMGNYTNYTNAARGCNMGNGAYGAYGAY TCNYTNATHTCNYTNTGYCARYTNYTNACNACNGTNGGNAGYYTNYTNGAYATHGAYAAR GCNAARCARMGNATGGAYCARTAYTTYACNCARATGTCNAARATHGCNGAYGARCARAAR TCNMGNATHAARTTYACNYTNATGGAYGTNGTNGARYTNMGNMGNCAYCAYTGGGTNCCN MGNAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GTNGARGAYYTNACNACNGTNAAYAARCARTCNATHMGNMGNATHAARAAY AAYGTNGCNTCNAARMGNTCNMGNGARCARMGNAARCARAARTTYGTNGARATGGAYCAR GARGCNGAYGARYTNGTNCARAARAAYGAYGARYTNMGNGARAARATHGTNGARYTNGAR MGNYTNGCNAARGARATGAARCARATHYTNGTNGCNAARATGGCNGGN------MGNGCN MGNGGNACNNNNNNNYTNAAYGCNYTNYTNCCNMGNTTYTTYAARAAYCCNAAYTGYTTY YTNTGYCCNGGNAAYACNGAYATHATHATGACNAAYGAYTCNGGNMGNACNYTNGTNATH GAYTTYYTNGCNCCNCCNACNCARGARGGNTTYTAYCCNGCNGCNGCNGAYTTYGTNAAR GARTTYAARAAYGARAARGTNMGNCCNCAYTGGGCNAARMGNCAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GGNAGYAAYYTNTCNCARMGNGTNACNGGNATHGCNTCNCCNAGYGAR------ GGNGGNGCNTCNGCNYTNCCNGGNTTYGTNTTYGGNGARTCNYTNGTNACNMGNGCNGTN AAY---ACNAAYGGNTCNAGYCAYCARCARGAY---GAYGGNAAYGARTCNGAYTCNGGN ---AAR---AAYCARACNYTNGARGARTCNGCNMGNGARTAYCARGCNMGNCAYGARAAY AARACNGARYTNAARGARGTNGARCCNATHACNGGNGARGARGARGARTCNAAYGTNYTN CARGCNAAYGCNAARYTNTTYGTNTTYGAYTGYACNACNCARTCNTGGGTNGARMGNGGN MGNGGNTTYATHMGNGTNAAYGAYATGGARATHGARGAYAAYACNGGNTTYCARTCNMGN YTNATHATGMGNACNCARGGNAAYYTNMGNGTNGTNYTNAAYACNAARATHTGGCCNGGN ATGTCNYTNGAYMGNGCNTCNTCNAARTCNGTNMGNATHACNGCNACNGAYACNGAYGAR ACNATHAARATHTTYYTNATHACNACNAAYACNAARGAYTCNGARAAYYTNYTNMGNGCN ATHGAYTGGMGNATHCARAARYTNAARATHCARGARGAYAAYACNCCNCARCAYAARTTY TCNMGNGTNGGNGAYAARMGNAARGCNGAYGAYTCNGAYTTYGARYTNCCNAGYAARAAY AARAARGCNAGYAGYCCNACNGAYCAYGCNGTNTCNGCNACNAARMGNGARGARTCNGAY AGYAGYGTNCARGAYCCNGARACNGARGCNTCNTGYGARAGYCAYTCNTCNTCNYTNACN ATHAARTCNGARTCNGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TTYTTYMGNMGNTCNGTNMGNTCN GTNGAYTCNTCNAARAARATGAARATGCARYTNTGGAGYGGNGTNGTNACNATHGTNYTN GTNGARGGNTTYAAYYTNGTNCCNATGGAYGAYAAYGGNYTNAGYGAYCCNTAYGTNAAR TTYMGNYTNGGNTCNGARAARTAYMGNAGYAARCAYAARYTNAARACNYTNCAYCCNMGN TGGYTNGARCARTTYGAYYTNMGNYTNTAYGAYGARCARYTNTCNCARATGGARATHACN GTNTTYGAYCAYGAYACN------------------------------------------ ------------------------------------------------------------ ------------------------------------GGNTTYGCNGTNGTNTTYYTNGTN AARAAYTCNAGYGGNGGNMGNYTNGCNYTNAARMGNATGTAYGTNAAYAAYGAYMGNGAY YTNGCNGTNTGYCARAARGARATHAARATHTCNAARGAYYTNAGYGGNCAYAARAAYATH ATHMGNTTYGTNGARTCNAGYATHGGNATGGGNCARAAYMGNGTNTAYGARGTNYTNATH YTNATGCARTAYTGYMGNGGNTCNGTNATHCARGCNATGAAYGARMGNATHAAYTCNGGN TTYTCNGARTCNGARATHMGNAARATHTTYTGYGAYATHTGYGARGCNGTNTCNMGNYTN CAYCAYTGYCARACNCCNATHATHCAYMGNGAYYTNAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------MGNCAYTTYGCNMGNTCNYTNAARGGNMGNATGTAY---AGYACNGCNGCN GCNCARGTNGARTCNMGNTCNTTYGGNGAYNNNGARCCNAARTGYTAYGTNAARAARYTN AAYAAYGGNATGTAYGTNGGNACNGTNGARAAYCARTCNCCNATHTCNMGNYTNGCNGTN GTNGCNAAYGCNGGNTCNMGNTTYGARTCNGGNGAYAAYYTNGGNATHTCNCAYYTNYTN MGNMGNTCNTCNAARYTNMGNACNGARAAYATGTCNGGNYTNGGNATHACNMGNGTNACN CARCARYTNGGNAGYGAYGTNACNACNATGGGNACNMGNGARTAYYTNTAYTAYAARAGY AAYGTNACNMGNAAYTGYGCNGGNAARATGGTNGARGTNYTNAARGARYTNACNACNAAR CARGTNTTYAARCCNTGGGARGTNTCNGAYYTNCARAGYCAYCCNGAYTCNYTNYTNYTN GAYYTNGCNGTNYTNAARACNCARCCNTAYGTNMGNGTNGTNGAYYTNYTNCAYGCNGCN GCNTTYMGNGAYACNYTNGGNMGNTCNYTNTAYGCNCCNGAYTTYYTNYTNGGNAARTAY ACNCCNGARCARYTNAAYCAYTAYGTNAARACNTAYTTYAGYGCNGGNMGNATGGCNYTN GTNGGNGTNGGNATHGAYCAYGAYGARYTNGARGARYTNGGNTCNCARTTYGARCCNTAY GCNTCNGCNGGNGTNCCNACNGARAARGCNGTNTAYCAY---GGNGGNGARYTNMGNGAR AAYACNGGNGGNGAYYTNACNCAYGTNGCNGTNGCNTGYGGNGGNGCNAGYYTNACNAGY AARGAYYTNYTNCCNTCNGARGTNATGMGNCAYATHATGGGNACNGGNCCNCAYATHAAR TAYAGYAGYGGNACNACNGTNGCNCARYTNGGNAARGCNGTNACNCARGCNACNGAYCAR CCNTTYCAYGTNTCNTGYYTNAAYGCNAAYTAYTCNGAYGGNGGNYTNTTYGGNTTYACN GCNGTNGCNCAYGCNTCNCARATHGARAARGTNGTNMGNGCNGCNGCNAAYCARTTYACN ACNGTNGCNTCNTCNGGNGTNACNGAYCARGTNGTNGCNMGNGCNAARAARCARYTNMGN GCNGARYTNTGYATGCARTTYGARAAYCCNGAYGTNYTNYTNAAYTGGYTNGGNGARCAR GCNYTNAAYTCNGAYCARATHYTNACNCCNCARGARATHTAYAARATGGTNGAYGCNGTN ACNYTNACNGAYGTNAARGCNGTNGCNAARAARATHGCNGCNTCNAARCCNTCNATGGCN AGYGTNGGNAAYGTNACNAAYGTNCCNTAYYTNGAYACNYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GGNGAYGCNACNCCNGCNGARTCNTCNGARTCNGCN GARTCNGGNGCNGCNAAYTGYACNAGYGAYGGNGCNGCNGAYACNGGNGARACNTCNGCN CCNAGYAARGTNCCNGTNGCNTCNACNGTNAARGCNGARTTYAARTGGGARGGNGGNGGN GARACNGTNYTNGTNAGYGGNTCNTTYAAYAGYTGGCARGARAARATHGCNYTNTCNAAR AGYGGNGAYGTNTTYACNGGNGCNYTNGAYYTNCCNGCNGGNGARTAYYTNTAYAARTTY YTNGTNGAYGAYCARTGGATGGTNAGYAARAAYTGYCCNACNCARGCNGAYAAYGAYGGN CARGARAAYAAYGTNATHYTNGTN------------------------------------ ------------------------------------------------------AARCAR AGYYTNAAYTTYTGGGAYCARGAYGCNTCNGTNATHGGNTGYTTYYTNTGGGAYYTNGGN YTNATHTGYYTNTTYATHGCNCARCAYTCNTTYATGGCNACNGARTGGTTYAARGGNAAR YTNCAYTCNTGGYTNMGNATHTCNGTNYTNGARMGNYTNATGTAYATHTTYTCNACNTGY ATHTGYYTNATGACNYTNATHYTNCAYTGGTAYTCNATHCCNGAYGTNTAYYTNTGGTAY ATGGAYACNCAYTCNMGNAGYYTNYTNTGGYTNTTYTTYYTNYTNTGYCAYGTNYTNGCN TGGTTYGTNYTNGGNYTNGARGCNYTNYTNATGGAYTGGCARGARATGYTNGGNATHAGY CARGTNATGAAYTAYCAYAAYGGNTTYAARCARYTN---YTNYTNATGAARGCNATHAAR YTNMGNGARYTNTAYTCNCAYATGMGNCAYCCNGGNGCNGTNYTNYTNACNTTYATHYTN TGGTTYCAYCCNYTNATGACNYTNGAYMGNGTNYTNYTNGCNTCNGTNTTYACNACNTAY ATGATHGGNMGNCAYAGYYTNGAYGARTCNCAYTAYTCNTTYGCNGARAARTAYTTYAGY ACNCARACNATGGARAARAARTCNCAYACNTCNGTNTGYTAYGARTAYGTNACNAARATH ACNTTYGAYGTNACNATHACNGAYYTNTCNYTNTCNCAYGAYAAYYTNCARATGAAYACN ACNYTNYTNATHACNACNATHACNGGNAAYCARTGGCAYGTNYTNYTNGARTCNMGNAAR ACNACNGGNACNTTYTCNCCNGAYTCNGAYYTNAGYGARYTNGGNTAYGAYAAYATHGAY GGNMGNACNATHCCNCCNMGNAGYATHYTNGAYGCNGCNGARAGYAAYAGYCCNGCNTTY YTNCCNGCNCARTAYCARACNTTYCARCCNCARACNTTYYTNAARCCNCAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AAYCARGARCAYCARACNATHMGN ATHYTNTCNGTNGCNAGYCARGGNAGYAAYYTNAAYTCNCCNATHAARACNCARAAYTAY YTNATHACNTCNACNMGNGAYTCNCCNYTNAARGCNCARACNTTYGTNYTNAAYACNACN AAYGGNAAYYTNACNCARGGNYTNAAYATHACNACNGCNGGNTCNCCNYTNGTNYTNGCN TCNCCNCAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNATHMGNACNGTNCAYAGYGTNATHCAYACNACN CCNGCNAARTTYYTNAARGARGTNATHYTNATHGAYGAYGGNAGYGAYTAYGAYTTYYTN AARGARAARYTNGARAAYTAYATHAARCARTTYAAYGGNYTNGTNAARYTNTAYMGNAAY CCNGARMGNTAYGGNYTNATHACNGCNMGNACNAARGGNGCNGARTAYTCNACNGGNGAY GTNATHGTNTTYYTNGAYGCNCAYTGYGARTGYAAYAARAAYTGGYTNCCNCCNYTNYTN GCNMGNATHAARTAYGAYMGNACNATHYTNGCNGTNCCNATHGTNGAYGGNATHAAYTGG GAYAAYATGGCNTAYTAYCARACNTAYGAYCAYCAYYTNCAYMGNGGNATHTTYGARTGG GGNTTYYTNTAYAARGARGGNYTNGTNCCNGARAARATHYTNCARACNMGNGARCAYGCN AGYGARCCNTAYGCNTCNCCNACNCAYGCNGGNGGNYTNYTNGCNATHGAYMGNAARTAY TTYTTYGARATGGGNGCNTAYGAYCCNGGNYTNAARATHTGGGGNGGNGARAAYTAYGAR YTNGCNTTYAARGTNTGGATGTGYGGNGGNAGYTCNGARTGGGTNCCNTGYTCNCAYGTN GGNCAYATHTAYMGNYTNMGNGGNGCNCCNTTYGGNGAYATHTTYMGNTGGTTYATGGAR AAYGTNGCNTTYGAYGTNTAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TGGMGNAAYAARTGYTGYCARYTNGARAARGTNATHAARACN YTNTCNGAYTAYTCNYTNAARGTNGTNGARAARCAYGARGARYTNYTNGTNAARTTYAAR AARAAYGARGCNCARTAYAAYAGYYTNAARGARAARTTYAARGARAARGGNGARCARATH AARCARGCNMGNGAYGTNYTNGCNCCNGTNTCNGCNGARYTNATHGCNYTNMGNCARAAR TAYGARATHGCNATHMGNTGYCARGTNGGNGCNGARCARTAYGCNTCNAARGTNAAYAGY AARAAYGTNGARYTNAARMGNCARAGYCARATGYTNATGAAYYTNGCNCCNAGYGTNAGY YTNGTNGARATHAAYYTN---GAYGARAARGARGARGARGARGAYGARAARGARTAYYTN AAYACNYTNAAYGAYCARATHGARGARYTNGARGAYAARAARGGNAARYTNAGYGCNCAR YTNTCNGARYTNAARAGYAAYTAYCARAAYGARACNGARATGAAYGCNCARYTNAARGAR MGNATHGARAARTAYAARGGNGARYTNAARCARGCNCARGCNTCNATHTCNAARTAYGAR GARATGATGGCNGARATHAAYGARAARTCNGARAARGCNTAYGARGARTAYMGNAARATG GARGAYAARTAYGARAARCAYYTNYTNATHCARGGNCARGCNGARCARGTNGCNCAYAAR YTNATGYTNCARMGNGAYCAYGCNGTNMGNGARAGYTCNATGYTNATGCARAAYGTNGCN GGNGAYACNMGNGTNATGAARGCNATGYTNGARGTNCARGAYGTNCAYACNAARATGGCN AAYATGAARGARGAYTAYGARMGNCARYTNAGYGAYYTNCAYGCNGARYTNAAYGAYYTN AARGARGAYTCNAAYATGCARAGYYTNGARGCNMGNAAYGARGARYTNGCNAGYGARTGY GAYTCNYTNCARGARAARYTNTTYGARAAYGARAARGARCAYGARAARYTNMGNTCNCAR TAYGGNACNYTNATHGCNAARTAYAARGAYYTNGARAAYAARTAYGAYAARGCNYTNCAY GCNCCNCCNCCNCCNCCNCCNACNCCNCCNCCNCCNACNCCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TGYGGNGAYTAYMGNGARGAYAGYTCNTAYATHGCNAGYGARGCNTTYATHAAYGCNATH GARMGNYTNMGNAARGAYACNGGNMGNAAYTTYGGNTAYYTNATHATHGAYGAYTGYTAY AGYCCNYTNAARGCNACNGARATGATHGTNAARGTNYTNAGYAARGCNYTNACNATHMGN GAYCCNGAYACNGAYGTNATHTTYGAYCCNAGYYTNGTNACNGTNGTNATHGGNGCNCAR TCNAGYCCNTCNACNATGGCNATGYTNCCNGTNYTNACNAARTTYGGNATHCCNATGATH TCNTAYAGYTCNACNAAYCCNAAYYTNGAYAAYMGNGTNATHTAYCCNTAYTTYTGYMGN ACNGTNAGYAGYGAYTCNGTNCARGCNGTNGCNATHATGMGNATHYTNAARCAYATGAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MGNGARGAYTCNMGNGGNGARMGN GARMGN---------GTNGAYMGNGAYMGNGAYMGNCCNATHMGNAARATHGGNAGYGGN MGNATHCARATHGAYMGNGAYGGNAAYMGNGAYTTYTCNAAYYTNMGNGARMGNTTYGAY GAYGAYMGNGARMGNGAYMGNGAY------CAYCCNTGGAAYMGNGARMGNGTN------ ------------------------------GARMGNGARMGNGAYGAYTGGGARMGNGAY MGNGAYMGNGAYMGN------MGNTTYGAYMGNTAYMGNMGNGCNGGNGAYGGNCARTAY NNNGANMGNNNNGAYMGNGAYTAYMGNGAYMGNGAYMGNGGNTAYGAYMGNTCNGGNMGN MGNMGNTAYMGNGARGARGARAARGARCCNGARTGGTTYACNGGNGGNCCNACNAGYCAR AAYGAYACNATHGARYTNMGNGGNTTYGARGTNGARAAYCAYAARTCNAAYMGNAARGCN GARYTNATGGARAGYGARCAYTCNGGNGAYAARGAYYTNCCNGARGCNGTNGTNCAYGTN AARACNCCNGAYMGNAAYTCNTCNGCNGARGARCAYCCNYTNGARATHCCNMGNACNCAY TGYYTNGCNCARCCNGCNYTNCARGARCAYCARMGNTCNCARCARCARGCNYTNMGNYTN TCNCCNTCNCCNACNACNGAYAARACN---TTYGAYYTNGARGARATHYTNAARGCNCAY YTNCCNATHAGYGARGARGCNGARGTNCAYGGNAGYMGNTTYTCNMGNTTYTTYGCNCCN GTNGGNAAYGTNMGNAGYCAYGCNTCNGARGAYYTNATGCCNCAYGAYYTNYTNGAYGAY AGYMGNYTNAGYCCNGCNGTNCCNTCNCCNCAYCAYCAYTAYCAYGCN---CCNCCNCCN TCNTGYTAYGGNCCNAAYTCNGCNGGNGAYAAYGCNGGNACNYTNCCNGCNTCNGTNACN GCNYTNTTYAAYAGYGCNGCNGCNGGNGGNATH------CCNCCNYTNTCNAGYAAYGGN AGYTTYAGYACNCARGAYGCNGARGCNCARYTNAARGCNATGYTNTTYGGNGGNCAYMGN GAYTCNGCNTCNTCNAGYGGNACNGCNTCNCCNGCNAGYYTNCCNCCNAAYYTNCARAAR MGNGTNAARACNGTNGCNGARYTNGARGCNGAYATGCAYCARAAYTCNCCNAARAARGCN TCNAGYCCNGTNTCNATGGCNGCNCCNTCNGGNCAYGGNGGNGAYATGGTNGCNTTYAAY AARYTNYTNACNYTNATHAAYGCNGCNTCNGARGCNAAYCARAGYACNACNTCNAAYATG TCNATHTCNAGYTCNCAYGGNGGNCAYGGNTAYGTNCCNAGYCAYAGYGARTTYGCNCAY GCNYTNATGMGNAAYAARGARTAYCARATGCAR---YTNCARCARTCNGTNCAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AGYCARGGNAGYTAYATHCCN GARACNATHTTYYTNGARACNTCNACNTGYCARTTYTCNCCNTAYAAYGTNCARACNGCN CARGTNYTNCCNGGNGTNACNYTNGTNTTYYTNTCNCARGCNCCNMGNCAYAAYYTNGCN GAYTCNYTNTAYCARATHATGCAYAAYATHCARGAYYTNATHCARGGNMGNMGNATHAAR YTNCCNMGNTCNMGNAGYYTNCAYGTNTAYGARATHGTNAAYTCNYTNYTNGGNAARYTN CAYAAYAGYYTNMGNAARYTNAARGGNMGNGARGGNTAYYTNATHTAYGARATHCAYTCN MGNTGGGARAARGARGAYGTNAARCAYAARYTNYTNAARTAYYTNGARAARGAYTCNMGN CAYCCNATHCCNCCNGARYTNGARTCNCCNATGTGGGARATGTAYAARAARYTNMGNGAR YTNTTYTCNYTNYTNTTYYTNTGYCAYCARMGNGARAAYCCNCAYYTNAARGARGTNYTN TCNAAYYTNMGNGTNMGNATHAAYTCNGARYTNYTNGAYTAYMGNGARTAYATGAAYGTN AARTCNCARMGNAAYATHACNATGACNAGYTAYATHGARGAYTTYCCNGGNATGATHCAY TTYATHTTYATHGAYMGNMGNYTNCAYCARATGACNGCNCCNTCNYTNAAYATHTCNTTY MGNGARGGNGARGTNGCNAAYGCNAGYACNTAYATGAARGAYTAYATHTGGMGNATGTAY CARCAYATGATGAARAARYTNATGGAYGGNTAYACNACNGTNATGYTNAARGAYGGNGAY TTYTAYTTYTCNTAYTTYYTNTGGTTYGARGAYAAYTCNMGNAAYCCNYTNCCNGTNCAR GARAGYTTYAARCCNTCNAAYAARYTNCCNTAYCCNGGNATHYTNTGYGGNTCNTTYTAY AARGAYATHATHAARCARTGYTTYCCNCAYGCNYTNCARAGYTCNGTNTAYTGYTAYGAR GTNTTYATGATGCAYGTNGGNAGYGTNCAYCCNCARTTYATHGCNTCNCAYTGYAARAAR YTNTCNGTNAARATGTGGGARATGTCNGGNGAYGCNTAYTCNTCNYTNAAYYTNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TCNGGNATGAARMGN TCNGARMGNCAYATGATGMGNYTNCARAAYATHATHGCNGCNGTNYTNAARGARAARGGN GTNMGNAARGGNGAYTCNATHTAYTCNTCNTGYTAYAARAAYYTNTTYAAYGTNAGYATH GTNYTNYTNMGNACNYTNCCNAAYTCNCARAAYYTNACNGTNGARATGAARTCNGTNGTN TAYAGYCARGTNCARCARATHATHAAYYTNGARAARMGNMGNTCNGGNATHGCNATH--- ------------------------------------------------------------ ---ATHAAYMGNAGYAARGAYAARATHGTNGARGARTTYACNGGNGARAAYGTNGTNGAR GARYTNAARACNGTNACNGGNGCNATGTCNCARYTNMGNCAYGARGTNATGACNAAYAAR CCNGCNGCNYTNATHAARGAYTCNCAYCCNGAYGCNGTNGCNTGGAAYTTYCARTGYAAR CARGARAARGARGGNGGNCARCCNCCNAARTGGTTYGAYAGYGCNTGGYTNTGGATGGAR TGYTAYYTNTAYMGNMGNATHCARGARGCNTCNTTYACNAGYACNCAYYTNAARTCNYTN GAYGTNTTYGCNGCNCARAARCARGAYTCNTTYATHAGYTCNTAYATGGCNGTNTCNACN YTNACNATGTAYYTNYTNGARGTNYTNGGNAARYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARGARGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CARTGYTCNYTNMGNGGNATHAAYAGYCCNYTNMGNYTNTTYCARYTNAAYGAYAAY GARGCNATHYTNATGTGYAARAAYGTNGAYTGYACNTTYATGTCNTCNTCNACNTGGGAR TCNYTNGTNGTNAARMGNGAYACNTCNMGNYTNGCNTCNAGYAARGGNAARMGNTCNTTY ATHCCNTGGCCNGAYYTNAARGGNYTNTAYMGNCARAAYAGYTGGGTNGAYAARGAYAAY YTNAARGARYTNYTNGAYGGNMGNGARCARGARYTNATHGGNTGGTAYAGYTTYMGNAAY CARACNAGYYTNMGNCCNTCNYTNAARGARACNTCNATHCAYMGNCAYYTNTCNACNGCN AAYATGGAYTCNGAYGARTTYYTNTTYYTNYTNTGYACNTCNTCNGCNACNTTYAAYYTN TCNACNCAYACNTGYGAYCAYGTNTTYYTNACNTTYGAYTAYAARAARTTYACNTCNGTN CCNATGGCNGTNMGNAAYYTNGGNGAYACNTCNAARTCNGARTAYAARCCNAAYGCNAAY TCNYTNGTNCAYTCNCARATGGTNCARGAYGTNYTNGGNAARTCNAARAARGAYTTYGTN AARCCNACNGGNCARATGGAYCARGTNGTNAARATGAARTCNYTNGTNACNTCNATHAAY AARAAYYTNGGNTCNGCNCARACNAARGTNAAYCARAGYGARGCNGTNYTNTGYYTNYTN CARGTNCARGTNCARTGYYTNMGNACNMGNYTNTCNCARYTNGARACNGARGAYATGMGN MGNACNTTYGARGARGARGARGARGARAGYYTNCARGARAAYTCNATGGARCCNGAYGAR AARGARCAR---------------------------AARMGNAARAARAARAARMGNAGY MGNAGYMGNAGYCAYGARMGNAAYMGNGAYAARAARMGNTCNCAYAGY------------ ---------------------------------------MGNGAYAARMGNTCNMGNAGY GARAGYAARGAYAARAARAARAAYMGNGAYAARGAYMGNGAYMGNMGNMGNAGYMGNAGY MGNGAYMGNGAY---AGYMGNMGNMGNMGNAGYAARTCNCCNMGNMGNMGNMGNAGYMGN AGYCCNYTNMGN---GARMGNGARCCNGARYTNACNGTNGARGARMGNGAYATHMGNACN GCNTTYTGYNNNCARYTNNNNGCNMGNATHMGNCCNMGNGAYYTNGARGARTTYTTYTCN TCNGTNGGNAARGTNMGNGAYGTNMGNYTNATHACNGAYAAYAARACNMGNMGNTCNAAR GGNATHGCNTAYATHGARTTYGCNGAYCCNGARTCNGTNTCNYTNGCNATHGGNYTNACN GGNCARAARYTNYTNGGNGTNCCNATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTNAAYGTNAGYGARGARYTN MGNYTNTCNACNYTNGCNYTNAAYAARMGNAGYATGGTNYTNGAYGARGAYAARTTYGAR GARCARTTYYTNMGNTGYAGYATHTGYAARGAYMGNTTYCAYACNGAYTGYYTNCCNMGN YTNYTNCCNTGYCAYCAYTCNTTYTGYCARAAYTGYGTNYTNCARYTNTTYCARTCNGCN AARAAYCARMGNCARMGNYTNCARTCNTCNATGMGNAAYYTNATGTTY------TCNACN GTNAGYATGAGYTGYCCNAAYTGYMGNGCNAAYTTYATGACNACNGARGAYGGNATHMGN AARYTNCCNACNGAYCAYMGNGTNGTNCARYTNATGGAYTTYGTNCAYCARACNGARMGN TAYACNATHACNTTYTGYTCNAARCAYAAYYTNCARCCNYTNAAYTTYTTYTGYGARCCN TGYGTNCARCCNGTNTGYMGNGAYTGYACNGTNYTNGAYCAYAARGARAAYGAYGGNCAY YTNGTNATGGAYYTNGARGARGCNYTNACNAARTAYACNCCNGTNYTNGAYTCNGCNATH ACNGARATGGAYGCNGARGCNGTNTGYYTNGARGARAARMGNATHGCNYTNGARTCNGTN ACNCARACNATHGARAARATHAARYTNGAYYTNYTNGAYAAYGTNAARGCNTGYATGGAR MGNYTNMGNMGNYTNATHAAYGARMGNGARAARATHYTNGARGCNAARGCNCAYGARGAR ACNGARAARGARAARACNAARYTNGCNGARAARGTNGARGCNYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TAYGTNAARYTNATGATG YTNACNGTNAAYCCNYTNGCNAARGAYACNTTYTTYAARGAYTAYCCNMGNYTNATGTCN CARGCNGTNTAYGCNTCNTTYTGYTTYGCNTTYCCNGAYTCNTAYMGNCARTTYGAYGAR ACNTTYAARGAYGARYTNATHTAYYTNGTNTAYGGNTGGATGGCNGGNATHMGNCCNTCN CCNMGNAGYTGGATHACNTGGGARATGTCNTCNYTNGARCCNCCNAAYYTNAARYTNMGN GARGARATGATGCARMGNAARAAY---AARAARATGAGYTCNYTNATHGAYTTYGAYTAY YTNGAYTCNYTNATHTCNACNAAYGCNAGYCARTAYACNTCNACNATGTCNYTNGCNCAR TCNACNTCNMGNTCNTCNGCNATHTCNAAYGTNGGN---ACN---MGNAARCCNMGNATG CAYGCNMGNATHAAYAARGCNTCNCAYAARCCNTCNTTYMGNGCNTCNTCNCCNAGYAAR YTNTAYTCNCCNACNTCNTCNCARGAYTCNAAYGCNATHGAYGCNGTNGCNGAYGCNCAR AAYAGYCCNMGNGTNAARGGNACNGAYMGNGARAARAARCARAAYGAYTCNYTNACNCCN GCNAARGAYCCNAARCAYYTNAAYGARGCNYTNACNCCNATHMGNGARATGACNAGYGAR GAYGARGAYGGNAAYATHGGNAARAARTTYYTNCAYATGTCNGTNAGYCARATHMGNGAR AGYMGNACNGARAAYAARTAYGTNATGAARTCNCAYCCNACNGGNMGNGGNTGYGARTTY GTNCAYGCNACNTTYAAYGTNGARGGNMGNAGYCCNYTNGTNGCNCAYTAYYTNAAYATG AARGGNYTNAARCARGARGCNGGNCARATGGTNTGGATHCARMGNGCNGARATHGARAGY YTNCCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TAYATGGARTCNTGYGGNGCNCAYAARTTYGGN YTNGCNAARATHATHCCNCCNAARGARTGGGTNCCNMGNAARTCNGGNTAYGAYGAYYTN GAYATGATGATHCCNGCNCCNATHGARCARGTNGTNACNGGNCARCARGGNYTNTAYACN CARTTYAAYGTNCARAARAARCCNATGCAYGTNAARGARTTYCARGARYTNGCNAAYTCN CCNAARTAYMGNACNCCNAGYCAYTTYGAYTAYGARGAYYTNGARMGNAARTAYTGGAAR AAYATHACNTTYGGNCARGCNATHTAYGGNGCNGAYATHAAYGGNTCNGTNACNGAYGAY GAYCARGAYATHTGGAAYATHAAYMGNYTNGGNTCNATHYTNGAYCAYGTNAARGARGAY TAYGGNATHCARATHGARGGNGTNGTNACNGCNTAYYTNTAYTTYGGNATGTGGAARACN ACNTTYGCNTGGCAYACNGARGAYATGGAYYTNTAYAGYATHAAYTAYYTNCAYTTYGGN GCNCCNAARTCNTGGTAYGCNATHCCNCCNGARCAYGGNCARMGNATGGARMGNYTNGCN CARGGNTTYTTYCCNAGYAGYTTYAGYGARTGYCCNGCNTTYYTNMGNCAYAARATGTCN YTNATHTCNCCNCAYATHYTNAARAARTAYTCNATHCCNGTNAAYAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GTNGTNAARTGGGGNCCNAARTAYMGNYTNGAYACNGCNYTNGCNGAY YTNGTNGCNGGNYTNACNGTNGGNYTNACNGTNATHCCNCARGGNYTNGCNTAYGCNCAR ATHGCNAAYYTNCCNCCNCARTAYGGNYTNTAYTCNGCNTTYATGGGNTGYTTYATHTAY TGYTTYATGGGNACNTCNAARGAYATHACNYTNGGNCCNACNGCNATHATGTCNYTNATG ACNGCNACNTTYGCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGAYTCNCAYGAYGTNTCNGARYTN YTNMGNGAYTAYACNTCNYTNATHYTNGAYAARGARAARAAYAARGTNCARTGYAGYYTN ACNAAYCAYGARATGCCNCCNAAYMGNAAYGTNATHGARTCNTAYGTNAAYGGNAARAAR TTYAARAARGCNGCNGCNATGAARGARTTYGAYTAYGAYATHTAYAARAARCAYATHGTN CARAGYATHAARMGNAARCAYYTNCAYGARYTNTTYTGYAARYTNACNYTNMGNCAYATH GARAAYTCNCCNAARGCNATHYTNMGNCAYATHATGGGNMGNAARTGYCAYAAYGCNYTN TCNMGNTGGGARAARTGYCARGARACNGGNGARAARTTYGTNCCNCAYGTNMGNMGNCCN GCNAARMGNYTNCCNGGNTCNGAYGARAAYACNAGYAGYGGNGGNTGYAGYAARTTYGAY GAYGAYGGNAAYGAYGAYTCNGAYAAYGAYGAYATGAGYGAYYTNTAYCCNGARGARGAY TTYCARGAYGGN------------------GGNGAYMGNGAYAAYGARGAYGARTCNGCN AAYGARAAYAARGCNAGYGAYGTNGARAAYGGN--------------------------- ------------------------------------------------------------ AGYAAYAARCCNYTNCCNCCNGGNTCNATGGGNTGGCCNATHGTNGGNGARACNATHCAR TTYYTNACNAARGGNTCNTCNTTYTAYGTNGARMGNTAYMGNGCNCAYGGNAAYGCNTAY AARACNCAYATHATGGCNTCNCCNACNATHMGNGTNAGYGGNGCNGAYYTNATHMGNGAR YTNACNAGYAARGARCCNCARCARYTNGTNACNAARTGGCCNAARCCNATHMGNTCNATH GTNGGNTCNMGNAGYYTNATHGTNGTNGCNGGNCARGARCAYMGNGCNYTNAARAAYATH GTNCARAARGCNATGAGYCCNACNMGNYTNGCNGAYTAYYTNCCNTGYATHCARGARCAY GTNMGNTCNAAYATHYTNTCNTGGTGYGAYAARGGN------------MGNATGYTNGCN TTYCCNGCNTGYGARAGYYTNGTNAGYGAYGTNYTNYTNGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MGNTCNMGNMGN GARGTNTTYGARGGNGAYCCNMGNGCNYTNAAYGARACNMGNCARAARATHAAYGARGAR TTYMGNAARAAYYTNGARGARAGYGAYATHTCNAARGTNGARGARAARYTNCAYYTNGCN GAYGAYGTNGCNTAYYTNYTNMGNGGNACNGTNYTNCARYTNCARCARAAR------GAY GARGARACNTAYGARYTNMGNATHACNAARAAYACNATHYTNCARGARAAYACNCCNTAY GAYYTNACNAARGARATHCCNGCNGTNCCNMGNAARAARAARTGYGCNGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TAYYTNGCNAAYGAYGTNGARGARGAYGARGAR GAYTTYAARTAYGARATHTTYCCNTGGATHYTNGGNCCNTCNTGGMGNAARAARTAYAAR GGNTTYYTNAARYTNMGNGAYYTNYTNTTYAARMGNGTNGAYTAYAARGCNATHGTNAGY MGNAARTGYTGYGAYGARGTNMGNAARACNAARTCNGAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNTTYAGYCARTGYGTNGAYTGGYTNACNTCNGAYAARGARTCNYTNAAR ACNYTNGGNGCNYTNGCNATHGGNAAYTTYGCNMGNMGNGAYTCNTAYTGYATHGARYTN GTNGAYATGGGNATHGTNGGNAARYTNGTNYTNYTNYTNAARTCNAAYTCNGAYGCNGGN TTYTAYYTNCARCAYGCNATHYTNAGYTCNYTNMGNAAYYTNGCNATHCCNGTNGCNAAY AARCCNMGNYTNYTNGARGARGGNGTNATGGARATHTGYYTNTGYYTNATHAAYTCNGAR GTNATGCCNGTNGTNTTYAARYTNYTNGGNGTNYTNMGNATGYTNATHGARGGNCARGAR TCNGCNGCNGTNAARYTNGGNCARGARMGNGCNTTYYTNGAYTGYYTNTTYGARTGGTGY TCNATHGARGCNCAYGCNGGNGTNAARGGNGARGCNCCNMGNYTNATHGCNTCNYTNATH AARAAYAGYCAYTCNGGNGCNGTNGTNCARAGYYTNATHMGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARGTNGGN ACNMGNGTNGCNYTNAAYYTNACNGARAARYTNGARAARMGNATGGGNAARGARGAYGCN CARAAYTTYTTYAGYAAYYTNGARAARGARAARTGGATHAGYAGYACNMGNGAYGGNAAR ATHTCNYTNTCNATHMGNACNATHYTNGARYTNGAYCARTAYYTNCARGAYATGTTYCCN AAYTTYATHAARAARTGYAAYYTNTGYACNAARATHTGYYTNCARGCNGARACNTGYGCN AAYTGYGGNATHAARYTNCAYTTYCAYTGYYTNAARAAYYTNYTNTCNMGNTCNGARGAR GAYMGNMGNTGYCCNGCNTCNCAYTGYMGNGARMGNTGGGGNACNATH------------ ------------------------------GTNTAYGARCARTTYGTNMGNYTNCARTAY TCNGTNAGYATHAAYGTNCAYGGNATGAGYCAYATHYTNAARGCNTAYTCNYTNCCNTTY TTYYTNAGYACNGGNGCNATHCARACNYTNGARYTNATGGGNTCNMGNYTNTGGTAYATH TCNACNGCNGAYYTNTTYGARGGNACNTTYCARCARAARGAYTCNYTNCCNTGYGAYGAR TTYATHGCNATHYTNGAYAAYMGNYTNAARAGYACNTGYCCNAARAARMGNGGNYTNTCN ACNAAYGGNNNNCANTTYYTNNNNAAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNYTNTCNGAYGTNYTNCCNACNTGYTTYCAYAARGTNTCNTGYTGYAGYGCNGTN ATGGTNTGGYTNYTNAGYATHGTNTCNATHCAYTCNACNCCNYTNGTNGTNGARGTNTGY AGYAARAAYATGCARAAYATHATHCARAAYCARAARGTNTCNCARATGGGNAGYMGNAGY AARACNACNCARAGYTGGTCNCCNACNCCNYTNCARYTNTGYCAYATHTTYGCNAAYATG GGNGCNAAYCCNACNGARYTNYTNGGNGARCARAARYTNTAYATGGAYGAYCARATHMGN AARYTNYTNTCNMGNTTYAAYAAYGARAAYCARMGNCARGGNGARATHATGGGNACNACN ATHACNGTNCAYAAYTGYCARCARATHTTYAARATHYTNGCNMGNTGYTTYCARGCNMGN CCNAAYTAYAGYACNGARGARYTNAAYYTNTTYYTNYTNATGATHTTYAARGTNTCNYTN GAYAGYGCNTTYAARAAYTGY---YTNCAYMGNATHTTYCAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYTGGTCNTTYAARYTNGAYGGNATHTTYAAY AAYGCNGAYCARGARGTNGTNTAYAAYACNGTNGCNTCNGAYATHATHACNGGNTCNYTN GAYGGNTAYAAYGGNACNYTNATGTGYTAYGGNCARACNGGNGCNGGNAARACNTTYACN ATGACNGGNGCNACNGARAGYTAYMGNCAYMGNGGNYTNATHCCNMGNGGNATHTCNCAR YTNTTYAARCARATHGARGAYMGNYTNGARTAYAGYATHACNGTNMGNGTNTCNTAYATG GARATHTAYAAYGARGGNATGGTNGAYYTNYTNGGNTCNYTNCCNGARCCNGTNTGG--- ---AAYGGNAARGARACNGTNATHAAYCCNGAYCCNYTNATHATHTCNGARAGYCARGGN GGNYTNTAYGTNAARGGNYTNTCNTGYCAYYTNGCNCARAAYGARGARGARGCNYTNAAY YTNYTNTTYGARGGNGARACNAAYMGNTCNATHTCNGCNCAYCARYTNAAYAARCAYTCN TCNMGNTCNCAYTGYATHTTYACNATHTAYYTNGARTCNMGNTCNMGNGTNCARTCNAAY GCNAARTAYACNGTNTCNAARGTNAAYTTYGTNGAYYTNGCNGGNTCNGARMGNATHGGN AARACNAARTCNGARGGNAARACNAARGARGARGCNATGTAYATHAAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GARATHATHTTYGARTGGAAYATHTCNAAY TAYTCNGAYAARTTYAAYGCNGARTGYTGYCARGARMGNGTNAARACNGTNTCNAGYCCN TTYTAYATHAGYCAYCAYGGNTAYYTNGCNCARTTYGARGCNTAYYTNAAYGGNAAYGGN TCNGGNCARGGNMGNTGYATGTCNGTNTTYYTNMGNATHATHAARGGNAAYTAYGAYAAY CARYTNAARTGGCCNGTNCARATGTCNTTYATHGTNGTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYTCNGGNGTNGARGTNATHGGNCAYATHTAYYTNAGYGTN GAYACNGGNAARAARATHGAYTAYATHYTNAAYGARAARGTNTGYAARACNGAYGARAAY AGYGTNACNTTYATHAGYAAYAGYTTYCAYGCNCARCCNGCNGARAARCCNAARCCN--- ---YTNAARAGYGARAARCCNACNGARGTNTCNGGNAARYTNACNGAYGAYGARGAYATH ATHYTNATGGAYGARCCNGCNAGYACNAAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNTGYATHCCNATGTTYATHGTNGAY GCNTTYACNMGNCARMGNTTYCARGGNAAYCCNGCNGCNGTNTGYYTNATHAAY------ ACNGAYYTNTCNGAYGAYGARATGCARAARATHGGNGCNGARATGAAYYTNTCNGARACN GCNTTY------GTNGCNGAYGGNCARGAYGAYTTYTCNTCNGGNAAYGARTTYGGNYTN MGNTGGTTYACNCCNAARACNGARGCNAAYYTNTGYGGNCAYGCNACNYTNGCNTCNGCN GCNGTNYTNGTNGAYGCNATHGGNAAYCARAARGGNMGNATHTGYTTYAAYACNAARAGY GGNCARYTNGTNGTNAGYMGNGGNGARAARCCNGGN---TTYYTNTCNATGGARTTYCCN YTNAAYAARCCNGCNCCNYTNGARCCNAAYCARGTNGARAARYTNYTNCARGTNTGYGTN GARCARMGNAGYCARATHGARGAYGTNYTNTAYTCNCCNGCNACNAAR---AARYTNYTN ATHMGNYTNAARGAYAAYATHCARAARCARTAYYTNGARAARYTNTCNCCNCARATHAAY TCNATGATHGARTGYGARCCNACNGGNTTYGTNAARGGNGTNGGNATHACNYTNAARGGN TCNAARAGYAAYGGNTGYGTNGAYAAYGAYGGNCARGARTAYGAYTTYGTNTCNMGNTAY TTYGCNCCNTGGGTNGGNATHCCNGARGAYCCNGTNACNGGNTCNTGGCAYACNGTNTGY GGNCCNTAYTGGGCNGARCARYTNAAYAARACNAARYTNTAYGCNMGNCARGTNTCNCCN MGNGGNGGNGAYYTNTGGGTNGARGTNGARGAR---AARGTNATHYTNYTNGGNCARGCN GTNATHAAYYTNCARGGNACNTTYCARYTNATGGGNAAYAAYCCNAARAARCARTCNAAR TCNTTYAARGTNYTNCARTGGATGACNGARACNGARAARGAYGAYGGNTCNGAYCARGGN AARGARGCNGCNACNGARGARACNACNCCNAARGCNAARAARCARYTNGAYCCNGARMGN MGNCAYAAYGCNCCNGAYGAYGARATGMGNTTYAGYGGNYTNCAYACNMGNGCNGAYATH CCNTCNAARGCNTTYAGYAARYTNCARMGNYTNTCNTCNMGNGARGAYGAYGCNCCNGCN TCNAAYGGNCARAAYAGYGTNGAYGTNGGNGAYYTNCCNGAYACNYTNGGNAAYGARGAY ATGGTNGAYMGNMGNTAYAARGGNGGNCAYATHCCNTCNAARYTNTTYAARACNYTNCAR ATGTCNGTNGGNGAYGAYGAYGAY------------------------------------ ------------------------------------------------------------ ------------------------------------TCNGARAARTCNGARGARGTNTTY ACNTAYATGTTYGAYAAYGGNATHGGNCAYAARGCNGCNGCNTTYTAYATHGARTGGGCN ATGYTNYTNGARYTNTCNGGNGAYACNAARMGNGCNGAYGTNATHTAYACNGARGGNYTN AAYMGNYTNGCNGARCCNMGNGAYYTNYTNYTNCARMGNCAYCARCARTTYCARAGYMGN YTNGCNMGNAAYATHATHYTNCARAGYGCNGARCCNAGYGGNYTNGAYATGGARGTNMGN CARGARGARAARMGNACNGTNYTNGGNMGNYTNAARGCNGTNGGNGGNAARCAYAARGTN GGNACNGCNMGNACNGGNACNGCNAARYTNGGNTCNGCNGGNYTNYTNMGNACNCARTCN GCNGCNGCNCCNGCNCARGTNCCNAARGGNTTYTCNGTNTTYACNGARGAYGAYACNTCN GCNCCNCARCCNCARGARACNCARGARTGGAARTCNATGCCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGGNAAYGGNATG AAYAARATHYTNCCNGGNYTNTAYGTNGGNAAYTTYMGNGAYGCNAARGAYGARAARCAR YTNAARGAYAAYAAYATHACNCAYATHYTNTCNATHCAYGAYAAYGCNAARAARATHYTN GCNGAYAARGARTAYYTNTGYATHCAYGCNTCNGAYACNTCNGAYCARGAYYTNAGYAAR TTYTTYCCNCARGTNATHMGNTTYATHCAYAARGCNMGNYTNGARGGNGGNTCNGTNYTN GTNCAYTGYYTNGCNGGNGTNTCNMGNAGYGTNACNGTNACNGCNGCNTAYATHATGACN ACNACNGGNYTNGGNTGGMGNGAYGCNYTNAAYGCNATHMGNGGNGCNMGNAGYATHGCN AAYCCNAAYTTYGGNTTYCARAARCARYTNCARCAYTAYGAYAGYGARCARGTNGARGAR GARMGNAARAARYTNAARYTNCARTTYCCNCARAAYCAYTTYAAYGAYGARGARGARTGY MGNCARAAYYTNCAYTGYTTYCARCARTAYGTNATGACNGGNACNYTNCCNTCNMGNTCN GAYCARYTNTAYCCNYTNCCNCAYMGNGCNTAYCARGGNCARGCNYTNCAYATHGCNAGY CAYGARTGYYTNAARATGCARTTYCARAGYYTNMGNGARCARYTNCARGCNAARACNGGN ATHGAYCCNGTNGTNYTNCCNGTNGARCCNAAYTCNAGYGTNGAYTTYGARTTYCAYTCN GARTAYGCNAGYGARGAYCCNGTNYTNGARATHTCNYTNTCNTGYTCNMGNYTNTCNACN GAYAAYGCNGAYGTNCCNCCNAAYGCNYTNGTNGTNGTNCAYACNATGYTNCCNCCNYTN CARCARATHTGGATGCAYCAYAAYCAYACNGARATHGTNGARAARAAYAGYTGYCCNCAY TTYYTNAARACNATHGGNTTYGGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNTGGCCNGARGCNCARGTNGARATHTTY GGNAGYTTYMGNACNGGNYTNTAYYTNCCNACNAGYGAYATHGAYYTNGTNGTNTTYGGN AARTGGGAYACNCARCCNYTNTAYACNYTNMGNGARGCNYTNYTNAARAARAARGTNGCN GARCCNGAYTCNYTNAARGTNYTNGAYAARGCNTCNGTNCCNATHGTNAARYTNACNGAY GTNGARACNGARGTNMGNGTNGARACNAARYTNTGYTCNAAYTGYACNMGNGAYATHTCN TCNGCNAAYTTYGTNATGCAYGARATGCAYTGYMGNMGNCAYATHGTNYTNTGYGAYCAR TGYAAYGARCCNATHCCNMGNYTNGARYTNGGNCARCAYTTYAAYGAYGTNCAYGCNAAR YTNCCNTGYGARMGNTGYAARCARGARGTNGCNMGNAGYGARATGGARAAYCAYYTNGAR MGNGAYTGYACNAARAARCCNATGACNTGYAARCAYTGYGARYTNTCNTTYCCNCARGAY GARTAYAAYAGYCAYCAYGAYTAYTGYGGNAGYMGNACNGARTGYTGYCCNYTNTGYCAR CARTAYGTNATGYTNAARGAYATGACNCARCAYGARMGNTCNGGNTGYACNTGYCCNGAR CCNAAYCCNGCNGCNCARTCNGCNYTNGCNGAYCCNTTYCARATGGCNTAYYTNCARGAY TTYYTNGAYTCNCCNCARTTYMGNMGNGTNGAYGARATHCCNGAYTTYACNGGNMGNYTN CARMGNMGNYTNAAYGARAAYGCNGARTTYAAYTCNMGNGTNAAYAARMGNAAYAAYTTY ACNAAYACNYTNACNACNACNACNMGNGGNMGNTCNAAYGTNAAYACNGAYMGNGCNTTY AAYTCNTTYCCNCCNMGNGGNATHCCNCCNGAYATHGAYTAYGAYACNATGYTNGCNYTN CARYTNGCNCAYGARGAYTGGGCNGARGAR---------------------------GAR ATHACNMGNGGNAARTGGATHGTNGTNAAYACNATHTCNTAYYTNGAYCCNAARGGNAAR GARMGNYTNTGGGARAGYGTNTCNMGNACNACNAARCARYTNAAYGARGCNGAYGCNGTN GGNATHATHGCNGTNTTYCAYGAYCCNGTNCARGAYTGYMGNAGYATHATHYTNGTNMGN CARTAYMGNCCNCCNATGGARAAYTAYACNATHGARTTYCCNGCNGGNYTNATHGAYAAR GGNGARACN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATHTCNGTNGGNCAYAARCCNGGNCARGARGARGGNGTNATHYTNYTNATGYTNTGY ACNGCNCARAAYATHAAYGGNACNAARTAYYTNYTNMGNCARAAYGTNGARCARATHTTY TCNAGYTTYYTNCARGARGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AGYAGYAAYMGNAGYAGYMGNCAY MGNAARAARGAYGARAARGAYMGN------------AGYAARGGNAARCAYGAYMGNMGN GGN---AGYGAYCAYCAYCAYMGNAARAARMGNMGNMGNMGNMGNGAYAAYAGYAAYAGY AGYGARAGYAGYAAYGARAAY---------AGYCARCAYCAYCAYCAYAARAGYAARMGN AARAARMGNMGNMGNACNGAYAARAGYCCNAGYGTNGARGTNATHGARGAYYTNAGYACN CCNCAYATHATHGARGAYAGYCCNACNCAYGAYGCNTCNCCNTCNTCNTCNGTNYTNYTN CARCAYACNGARGARAAYAGYYTNGAYTCNGTNMGNGARACNCARGTNTAYACNGGNGCN TCNTCNGCNTCNACNCCNACNMGNACNTCNGCNACNGCNGCNTCNTCNYTNCAYATGGAR CCNGAYGGNGARAARGARGAYGAYGARGARGARGARGGNGARATHCARAAYGAYATHAAY GGNGARCARATGGAYACNGARGARGTNGCNGGNATGGARGGNAARGAYTCNGARGTNGAR GCNTCNACNGCNGTNATHAGYAARCCNCCNCARATHACNATHCCNYTNCAYGTNGCNGCN ATHAAYCCNCCNGARYTNTAYGGNGCNGCNTTYTCN---GCNAGYGCNGCNGCNGTNACN GCNCARCCNGGNCCNGCNGGNGTNGARACNTCNACNCARCARGAYACNGCNGAYGGNGAY MGNGCNGGNAARAARAARAARAARGARAARAGYGGNAARGARAARTCNYTNGCNACNGGN ACNAGYYTNATGATGAARAARAARMGNGTNTCNTCNATGGTNCARAARTGGCARCARGTN AARAARGARGTNGARAARGARGAYMGNGCNAARGARYTNMGNCARGCNGCNATHMGNGAR AARATHAAYCARYTNAAR---------------------AAYGGNAGYGCNCCNGARYTN YTNACNCARGTNTCNCARGARMGNGGNTGGGCNGARTAYGAYGARGCNATHCAYAGYMGN GAYGAYTGGAAYATHTGGTGGMGNACNAGYCAYTTYMGNACNGGNGAYTAYACNAAYYTN CARCCNTGGCARTGGATHAAYCAYTTYCCNAAYTGYACNYTNATHACNMGNAARGAYGCN YTNTGYMGNAAYATHMGNAARATGMGNGTNTCNCAYGGNYTNCAYGTNTAYAAYTTYTGY CCNYTNGCNTTYAAYYTNCCNAAYGAYTAYACNAARTAYGTNTCNGARTAYGCNAGYYTN AARCARCAYMGNAARAARGARGAYGCNCCNACNGCNTGGATHTGYAARCCNGCNGARTCN TCNMGNGGNMGNGGNATHTTYATHTTYAGYGARYTNGCNGAYYTNCAYTAYGAYTGYAGY GCNGCNGTNCARCARTAYATHGCNGAYCCNYTNYTNATHGGNGGNTAYAARTTYGAYATH MGNGTNTAYGTNGCNATHCCNAGYTTYCARCCNYTNCARYTNTAYATHCAYGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TAYAARATHGARGAYACNTCNATGYTNTAYATHCCNAAYGAY TCNGCNMGNCARGTNCAYCCNGAYGARAGYMGNTAYGTNAARATGTTYCARAGYGTNGAY YTNTCNAGYAAYTTYTAYTTYAGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNGARGARATGYTNTCNYTNTAYAAY AARAAYAGYCCNCCNCCNGAYCARGTNMGNAARCAYCARTCNATHTTYTCNAARGAYAAY YTNMGNCCNATHGCNATGTCNYTNYTNACNGARGAYGARCARMGNYTNATGTCNCARGGN TAYAAYAGYTCNGTNGTNYTNMGNGCNGTNMGNGGNGGNACNGCNGAYMGNGGNMGNGGN MGNGGNMGNGGNMGNGGNGAYGGNTAYGAYGAYMGNMGNGCNYTNAGYMGNGAYGARGAR CAYMGNGAYCCNMGNMGNATHACNGARTCNTAYGARAAYGTNCCNGARTGGGTNGARGAY GAYGTNGARGGNGAYCCNGGNACNTTYGAYTCNAGYGGNGTNTTYYTNTCNACNAARATG CCNGARTCNGGNTCNGARAGYTTYYTNCAYATGGARAARTCNYTNCARAAYYTNYTNGCN GARATGACNTCNGGNTCNGARAAYAARTTYGGNAARGARATHGAYATHTCNAARGGNGCN YTNCCNYTNACNCAYGARAAYGCNAAYAARTGGTTYTAYMGNGAYCCNCARGGNGARATH CARGGNCCNTTYMGNGGNGARGAYATGGCNCARTGGTTYAGYGCNGGNTAYTTYACNATG AGYYTNACNGTNAARMGNGGNTGYGAYGAYTCNTTYAGYCARYTNGGNGARYTNATHAAR MGNTAYGGNMGNGTNCCNTTYYTNCCNGGNGCNCCNYTNCCNCCNYTNATHACNAGYAAY AGYTCNCCNGARGARATHGGNCAYGTNTCNACNGCNATHCCNCCNYTNTCNATGYTNATH AGYYTNGTNGCNCCNGCNATGCCNTCNYTNCCNGAYCCNYTNGTNYTNCARCARATGYTN YTNCAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARGCNAARAARCAYYTNGCNGARGARMGNAARMGNGAR TAYAAYGAYATGYTNCARGCNAARATGAARTCNAARTCNAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CARMGNCARTTYACNCCNACNGAYCARGTNAGYCCNACNMGNGGNGARTAYGARAAR MGNATHCARAARGARAARGARCARMGNGARTAYAARGCNYTNYTNGAYYTNCARCARGAR CARAARCARCARATGGTNYTNYTNCARCARGGNGTNCCNTAYGARMGNGTN--------- ------------------------------------------------------------ ------------------------------------------------CCNYTNTCNYTN TGGAARYTNGTNAARCARCARATHCCNCCNTTYGARCARGAYGARATHAARAGYATGYTN GGNACNCAYATHGTNGAYCARAGYYTNGARYTNCAYGARGARATHGGNGCNYTNYTNGAY ATHTGGMGNGAYATGMGN---GTNGARCARAGYGAYGTNAARYTNCCNTCNTCNYTNCCN GARCCNCCNAAYATGMGNGARMGNYTNATHCARGARATHATHTTYTTYGCNGARAAYGTN AARGARAARGCNCARMGNAARGGNATHAAYCCNGAYCAYATHYTNAARCAYCAYAAYACN GAYATHYTNGARTAYGCNTCNGARTCNAGYMGNCCNGGNTCNGCNTTYGGNAARTCNTCN MGNTCNTCNGAYGGNMGNGARACNCCNATGATGGTNATHTCNCCNGAYMGNATHTCNAAR ACNTTYAARGTNACNGAYGARGTNGARGCNGTNAAYGAYAARYTNAAYGTNAAYGAYTTY GAYGARGTNTGYTCNCAYYTNMGNTCNACNYTNGARAARGARGTNGARCARYTNATHAAY GAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GAYYTNTGY AAYCARGCNAAYGARGARTAYGTNAARGARAAYTAYGCNAARGCNGTNGAYYTNTAYACN GARGCNYTNGTNATGGAYAAYAARMGNGAYGAYATHTTYTTYYTNMGNGCNCARGCNAAY ATGCARYTNGGNAAYYTNGCNGAYGCNGTNATHGAYTGYGAYAARGCNATHGARYTNAAY GARTGYAAYGARAARGCNGTNATHAARAARGGNTCNATHYTNYTNCARYTNGGNGAYGTN AARCARGCNYTNACNATHTTYCARGARGGNCARAARAARTTYGARAAYGCNTCN---TTY GARGARTGGYTNACNAARACNGARCARMGNATGAARGARYTNGGNATHCARTCN------ ---------------------------------GCNAGYGCNCCNGTNAARYTNAARTAY GAYTGGTAYCARACNCAYTCNGAYGTNGTNGTNACNGTNYTNGTNAARAAYGTNCARAAR GARAAYYTNACNGTNGAYGTNGAYCARMGNGCNYTNAAYATHGCNYTNAARAAYAAYACN GARACNCCNAAYACNYTNAGYYTNACNYTNTCNAAYGAYGTNGTNGTNGARAARACNYTN ACNAARATHTTYTCNACNAARATHGARATHAARYTNMGNAARATGGARAAYATHCARTGG TCNAARYTNGARGGNTCNCCNGGNGAR---GGN---AGYGTNTTYGCNGTNCARGCNCCN ------------TCNGARGTNCCNAARTAYCCNACNTCNTCNCAYGTNTCNMGNGAYTGG GAYAARYTNGCNGCNGARGTNACNGARGARGARAARAAYGARAARYTNGARGGNGAYGCN GCNYTNAAYCARTTYTTYCARAARATHTAYGCNGAYGCNTCNGAYGARACNAARAARGCN ATGATGAARTCNTTYAGYGARTCNGGNGGNACNGTNYTNAGYACNAAYTGGTCNGARGTN GGNGCNAAYAARGTNGAYGTNAARCCNCCNGAYGGNATGGARTAYAARAARTGGGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------MGNMGNAGYMGNGGNMGNCCNCCNYTNTCNTCNGARGARAARGCNAARMGNGCN GCNGTNAARGARGCNTCNCCNATHMGNGGNMGNGGNMGNCCNMGNGGNTCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNGARMGNYTNTAYCAYTGGGCNGARTTYGCNCARGAYCCNYTN AARTCNTAYGCNACNGGNYTNYTNAGYGGNGCNATGGARYTNAAYGAYATGGCNGTNMGN TTYMGNGAYGARGGNYTNCAYATGGTNCCNATHATGYTNGARMGNYTNCAYACNYTNGTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CAYTCNCARATHMGN MGNTTYYTNMGNCARATHGAYGTNCAYTGYGGNCCNTCNGCNAGY---ATHTTYCARAAR GTNYTNMGNACNYTNTCNACNTGGYTNGAYYTNTAYAARGAYGGNAAYATGGTNATGAAY ATGAARGARAARATHACNGGNATHYTNAARAAYATHCCNGGNGTNYTNGAYGARYTNATH AGYTAYTTYYTNGAYGGNCCNYTNCCNGAYTGYCAYYTNGAYGAYTTYGARGARGTNAAY YTNGAYGAYGARGCNAARYTN------GCNGCNGAYGARTTYGARGARGTNGTNYTNCCN GAYGARMGNGARAAYTAYAAYACNAARATGTGYGCNTGYCAYTGYCAY---AGYAAYYTN CARGAYGARMGNYTNCAYMGNMGNATHAARCAYTGYATHTCNTGYAGYYTNAARATGTAY GGNAGYCARCCNGTNYTNAAYATGTCNMGNAAYGARTAYMGNCCNGTNTCNGTNGTNTAY CCN---------YTNGARGARAARGARAARYTNGTNMGNGCNAARAARGARGCNGCNCAR ATGGCNGTNGCNAARGCNMGNGCNMGNMGNCARCARAARGCNAAR------GCNAGYCCN CCNYTNAAYTCNACNGAYGARMGNACNATGMGNACNMGNAAYMGNGTNMGNAARAARYTN CARCARMGNMGNATHAAYCCNGAYGGNTAYTAY------CCNCCNMGNTCNCARGGNGGN MGNMGNAAYMGNAAYGGNGTNAAYGGNGAYGCNGGNATGCAYGTNGAYATGGGNATGGTN CAYGGNCARGAYAAYGGNGCNYTNGAYCCNGARGARGARAAYAAYYTNATHACNCARTGY YTNTCNACNATGCCNGTNCCNAARGTNACNGAYGTNGARTCNMGNATHGCNYTNATHCAR YTNTCNCCNCCNGARTGYGARTCNATGYTNGAYYTNTAYCCNTCNGARTTYAARTAYGAR YTNYTNYTNTCNGAYAARGGNMGNGARGCNAARTAYAARACNGTNTTY------------ ------------------------------------------------------------ ---------------------CARATGAARAARTGGAAYYTNTAYGARAARACNYTNGAR AARGARACNTCNAARAARAARAARAARGCNACNMGNAAYGAYYTNGAYGARATGMGNCAR YTNYTNGARGCNAAYGTNAAYCCNGAYGTNACNAAYGARGAYGGNYTNACNGCNYTNCAY CARTGYTGYATHGAYAAYAAYGARGARATGYTNATGYTNYTNTTYGARTTYAAYACNAAY GTNAAYGCNTGYGAYAGYGARATGTGGACNCCNYTNCAYGCNGCNGCNACNTGYGGNCAY ATGACN---------------------------------TCNATGATGGARAGYTCNTTY AAYTAYCCNYTNCCNCCNAARAARYTNTTYYTNATGGAYGAYACNAARGAYTCNTCNGAY TCNGARACNAARYTNTCNYTNACNACNGAYACNGARGAYAAYMGNYTNTCNCAYACNATH AGYATHGAYCCNGARACNACNAARGAYTCNGGNGCNTCNGAYTCNAAYGTNGARGGNCCN ACNCCNACNAAR---MGNGTNAARGGNTAYMGNGARGGNYTNGGNGAYGTNYTNGAR--- TCNAARMGNGTNTTYACNGCNGARCAYYTNTTYGARTAYCARTGGCCNCARGAYGGNGGN GARTGGCAYYTNYTNCARGARCARGTNAGYGARTAYYTNAARGTNAARTCNTTYAARMGN AARTAYCCNGAYYTNTAYMGNMGNATHTGYGAYAARGARGARAARGAYTTYYTNMGNGAR AARGGNGTNGTNTCNGARACNCARTCNGAYYTNGGNYTNACNGCNYTNMGNTGYGARGAR GTNTAYGAYYTNATGATGAARGAYTAYGGNGARAAYTAYCARGARTAYATHTCNGTNYTN CARGARAARCARAARAARGTNATHMGNGARAARCAYAARGARTAYGGNGTNTCNAARYTN GAYAARTCNAARATHGAYGCNTAYAGYAARAARGCNGCNAARTCNGCNGCNGARTTYAAY GCNAGYYTNATGMGNGARAARMGNGAYGARMGNMGNGCNTAYTTYGAYYTNCARACNTAY ACNATHCAYCAYTCNAARCAYCARTAYMGNAGYYTNCARCCNAGYATGACNAARATHAAR TCNTAYCCNGTNGCNYTNATHTCNGGNCARTAYCARGAYTGYATHMGNMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNCCNGARTGYYTNATHYTNTCNMGNGTNYTNGTN GGNATHCAYTCNGGNTGGAAYATHGCNYTNTGYCCNGTNTAYYTNGCNGARATHTCNCCN AARAARATHMGNGGNGCNATHGGNACNTGYCAYCARYTNGCNATHACNGTNGGNATHYTN ATHTCNCARATHTTYGGNYTNMGNGARYTNYTNGGNACNGARGAYYTNTGGCCNATGYTN TTYGTNTTYAAYGCNATHCCNACNYTNGTNTGYYTNGARGCNYTNGCNAARGTNGTNGAY CCNACNTAYCAYAAYGTNGGNTTYGTNTCNGCNAARGARATHCARCARGGNGAYTGYYTN TCNAAYTGYAARGTNYTNTGYTTYGGNGGNGGNTAYGAYYTNGGNTTYYTNGARGCNYTN GGNATHGGNGGNGGNMGNCARATHMGNGARTTYGTNCAYAARGGNGGNAAYTAYYTNGGN ATGTGYGCNGGNGCNTAYTTYGCNTGYGAYTAYATHGARTTYGAYAARGAYGGNCCNATH GARGTNGTNGGNGARMGNCAYYTNAARTTYTAYCCNGGNATHTGYMGNGGNCCNGCNTTY CCNGGNTTYGTNTAYATGTCNAARMGNGGNGTNCAYGCNGTNCCNGTNTCNTAYMGNAAY YTNYTNYTNGAYACNTAYATGCAYGGNGGNGGNTAYTTYGTNCCNTAYAAYTCNTTYCAY AARGAYGTNGAYGTNCAR------GGNMGNTTYGARTCNYTNGARAAYTGYCCNGARGCN ATHGTNAARTGYAARGTNGGNYTNGGNTGYGCNATHYTNTCNGGNGTNCAYYTNGARTTY YTNGCNCAYAGYYTNGAYAARGCNGAYGARAAYYTNAARGARGTNATGCCNTAYTTYTAY GARGCNGARGTNAARMGNAAYYTNGTNTTYATGGAYGTNYTNTTYCARYTNGGNGTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNACNGGNGCNAGYAGYTCNGGN------------GTNGAYGAYGARGARTAY GTNCCNCCNAARCCNGARGTNGARGARATHAARGARGAYGAYGCNYTNTAYTCNAARMGN TGYAARYTNTTYATHCARAARGARGGNCARTGGGCNGARAGYGGNATHTGYAAYYTNCAY YTNAARCCNGTNAAYGARACNAARACNCARYTNYTNGTNMGNGCNGAYACNAAYYTNGGN AAYATHTTYYTNAAYATHATGYTNTCNGCNTCNATHCCNGTNTCNYTNCARGGNAARAAY AAYGTNYTNATHATGGCNATHCCNAAYCCNCCNYTNAAR------GARGGNGARACNGAY YTNAARCCNGTNCCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GCNAAYGCNAAYGAYAAY AARGGNGGNATGATGAARAAYYTNATGGARAAYTAYGGNAAYYTNCARGTNTCNCCNAAR CCNGCNCCNAARGTNAARGGNTCNGARGCNGARGARTAYAARYTNMGNGARCARGGNAGY ACNAARYTNYTNYTNGAYCAYTAYAGYACNGARCCNGTNCCNGCNGCNGARAARCCNYTN CCNCCNMGNYTNGGNCAYGGNGCNGARGARATHGCNCARAARCAYACNGGNGARAARATG GGNCCNYTNATGMGNYTNGARGGNAARGCNAGYCCNMGNGARATHAARGTNGGNCCNYTN CAYCARACNTCNTCNGGNAGYAGYTGGGAYGARATHCCNCCNCARCAYMGNATGMGNCCN GARGGNGARGGNATHGCNCARAARAAYAGYGCNGAYTCNATHGGNGAYATHATGYTNCAR AAYAAYGCNGCNGTNCCNCARMGNAARGARGCNAARGTNYTNAARCAYYTNGARGARTCN GGNYTNCCNAGYAAYACNCCNGCNCAYMGNGTNMGNCAYGARGGNATHGARAAYYTNGAR AARGCNMGNAAYMGNCAYGARATGTCNGCNATHATGCAYGGNAGYCCNACNAARACNGAR GTNMGNCCNMGNACNGGNAARAARGTNYTNCCNCAYYTNCARMGNTCNGARYTNTGGGGN GTNTAYGCNAARMGNCARATHTCNAARYTNACNATHGTNGARTTYTAYGGNGCNACNGAR GGNGTNGGNYTNYTNATHAAYGCNTCNCARAARCCNGGNGCNATHGGNMGNATHTCNCCN YTNYTNAAYATHAGYCCNCARCCNCARGTNYTNGTNGARTTYGAYATGTCNACNGCNACN CCNGTNMGNGAYMGNAAYGGNCAYTGYATHAARGTNGGNCCNGGNAARCCNGGNYTNTTY YTNCCNTCNTAYCCNAARGARGCNYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CCNAARCCNTGGATGACNATHTCNAAY ATGGCNTGGTAYATGAARTTYGCNATGGGNAGYTAYGGNTGGCCNYTNTTYATGTAYGAR CAYYTNGCNACNGGNATGTGYMGNYTNTGYTCNAARTGYMGNTGYTGYTCNTGYATHMGN YTNACNAAYGGNATHTTYGARGAYAAYACNTGYCAYTGYAAYACNGCNGCNATHAARAAR YTNTCNGGNGTNACNAGYGAYGAYYTNATHTAYGTNACNTTYCAYAAYAARTTYAARGAR ATHCCNTTYTAYGTNGTNYTNGAYMGNGARAAYAAYACNGTNGTNGTNAGYATHMGNGGN ACNYTNTCNYTNCARGAYGCNYTNGCNGAYGTNTCNGCNAARGGNGCNGCNYTNGARATH CCNGGNGTNGARAAYAGYTAYTGYCAYGARGCNATGYTNGAYTGYGCNAAYTAYATHAAR ACNCARATHGARTGYYTNGGNYTNYTNGARACNGCNTTYTCNCAYYTNCARGGNGARGCN CAYYTNGTNYTNACNGGNCAYAGYYTNGGNGCNGGNATHGCNGCNATHYTNGCNGTNYTN ATGAARCCNAARTAYCCNAAYYTNATGTGYTTYTCNTTYTCNCCNCCNGGNGGNYTNATG AGYCCNAGYGCNAGYAARTAYACNCAYGAYTTYGTNTGYGCNGTNGTNYTNGGNAARGAY YTNGTNCCNMGNYTNGGNATGCAYACNYTNATHGAYYTNAARGTNAARGTNYTNMGNGCN YTNTGYCARTCNMGNGAYCCNAARTTYMGNATHYTNGCNACNGGNTGYYTNCARYTNATH TGYTGYTGYCARTTYGGNGCNGARGAYCAYACNACNAARGCNYTNGTNCAYGGNGCNCAR TAYACNGAYTCNAAYGCNMGNATHATGGARGCNATGACNATGCARGAYGTNYTNMGNYTN GCNGARAGYCARGCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ACNGTNGARTTYGCNGCNGCNTCNATGGARACNAARYTNGAYGGNTGGYTNAAR ACNYTNAARGARAAYATHATGACNGARYTNTCNTCNTCNATHGTNGCNAGYYTNGARTCN CARMGNCARGARCARTGYAARGARTCNAAYAARYTNGTNGGNGARMGNGTNTGYYTNGAR AARGARGTNAAYYTNYTNAGYGARATHATHAAYTCNATGGARCARAGYACNTCNMGNAAR GAYACNYTNATHGAYAAYYTNACNGARTCNYTNGCNACNCARAARGGNAARACNYTNATG GCNTTYAARTTYTAYAAYTGGAARACNAGYCAYYTNGAYAARYTNMGNGARAARTTYACN GARAARYTNGCNGTNCARTTYCAYGARGCNAARYTNAGYCARAARGTNYTNAARGGNTGG TTYGGNYTNATHCARGGNMGNTGGMGNTCNMGNGTNGARCAYAARTGYCARGGNCARGCN CARAAYGTNTGYYTNCARYTNTCNAAYGAYTAYGARTCNAARATHAAYTCNYTNAAYGAR ACNATHAARTCNYTNGARGAYMGNGTNTCNACNYTNCARGTNGARAARGARACNTAYGCN GAYCARGTNAARAARGCNTTYATGMGNGGNGTNTGYGCNYTNAAYATGGARGCNATGTCN GCNTTYAAYCARGARCARGCNGAYACNTCNTGYATH---GGNATGTCNCCNCCNTAYGAY ACNTCNCARAGYYTNGAYYTNGCNGGN------------------AAYAAYGGNAAYGCN AAYYTNGAYTTYGTNCAYCCNTGYAARACNCAYGGNGTNTCNAARTCNYTNATHGTNTCN TCNTCNTCNACNGAYYTNYTNATHAGYTCNAARTCNGARTCNACNTCNYTNCCNATHGTN CARACNATGGTNTCNACN---------------AARGGNMGN------------------ ------CCNAARCARTGYGCNCCNGGNAARACNAARATGACNCCNTCNAGYTCNAARAGY AARYTNCAYYTNYTNGGNCARGTNYTNTCNCCNCCNATGGCNTCNGTNGTNGTNGARMGN CAYCAYCCNGTNACNAARCARACNATGGGNAARGCNACNGCNGTNTGYTAYCCNAARATG GGNMGNAARAARATHCARATHGCNMGNATHAAYGAYGARMGNAAYMGNCARGTNACNTTY ACNAARMGNAARTTYGGNYTNATGAARAARGCNTAYGARYTNAGYGTNYTNTGYGAYTGY GARATHGCNYTNATHATHTTYACNAGYAAYAAYAARYTNTAYCARTAYGCNAGYTCNGAY ATGGAYAARGTNYTNYTNAARTAYACNGARTAYAAYGAYTCNGTNGTNAGYCARACNAAY AARGAYATHATGGAYATGYTNAAYAARAARGARAGYAARGGNGGNGAYATGGAYGCNGAY GAYGAYGAYTTYCCNATHTCNCCNMGNACNGAYGARAAYTAYMGNAARATHGAYGCNGAR TTYGCNMGNGCNATGAAYGAYGGNGGNATHAAR---CARCCNATHCARTAYCARATHCCN GTNCARGTNCCNACNTCNCARTAYACN---------ACNAAYATGGCNAGYGGNGGNTCN GTNATHGTNYTNCARCCN------------GGNCAYTCNGTNTCNAGYCCNTCNGGNAGY MGNGTNAGYCCNGCNCCNGGNAGYGCNACNCARATH---GTNGGNCAR---TCNGCNTCN ACNGGNCAYGGNCAYGCNATHCCNGTNGCNGTNCAYATGTCNGGNGAYYTNCCNMGN--- GTNGTNACNGCNTCNACNTCNACNCAY---------CARCCNATHATHGCNAARAARCCN AGYYTNAARGTNYTNATHCCNGAYMGNGGNCCNACNGTNATGCARTCNMGNTTYCARCCN GGNACNGCNYTNGAYACNCCNAAYGTNTCNATH--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GCNAARCARTGYGAY AARGARATHGAY---TCNGGNGCNTGYTAYAAYTGYAARGGNACNGGNCAYGTNCARMGN GAYTGYCCNGARGGNAAYATHMGNCCNTGYTTYMGNTGYGGNAAYACNGGNCAYYTNGCN MGNGARTGYCCNGARGARAARGCN------------GTN------------GAYGARMGN AARTGYTAYAAYTGYGGNGGNGTNGGNCAYYTNTCNMGNGARTGYCCNACNCCNCARMGN TCNTAYTTYTGG---TGYNNNNNNTGYGGNAGYCAYAGYCAYATHCARAARGAYTGYCCN GCNGGN---GGNTCNGAYATHCARTGYTAYAARTGYAGYAARTTYGGNCAYATHGCNAAR GAYTGYAAYGARGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CARACNGARMGNCCNATHAARTAYACNMGNAARTCNATHGAYTAYAAYGCN YTNGAYGAYATHGGNCAYGGNGTNMGNCARGCNTCNACNCCNMGN------------GCN ACNMGNTCNCCNTCNATHAGYAGYACNCAYAGYAAYCCNGCNAAYAAYCAYCARCARGCN CCNACNACNAARCCNCCNACNCCNCCNGTNTAYMGNGCNGGNTCNAGYGGNACNYTNGGN MGNGCNACNGGNGTNCAYTAYMGNGCNATGGGNCCNCCNGTNGCNCCNATHGTNGCNCCN GCNCARATHTCNGCNAGYAAYTAYCARGCNCAYCCNCARTCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AARMGNTAYYTNATHATHACN GCNGAYGAYTTYGGNTTYAGYGCNGARAARAAYMGNGGNGTNATGGARGCNCAYAARAAY GGNGTNGCNAAYAGYGCNTCNGTNYTNYTNAAYTGYACNGGNACNGAYGARGCNGTNYTN ATGGCNAARTCNTCNTCNATHTGYGCNGGNYTNCAYATGAAYYTNACNGARGGNAARCCN ATHTCNAARGARGAYTAYAARACNYTNACNGAYGARTCNGGNATHTTYCAYGGNAARAGY GGNACNTAYGARGTNATG------CCNMGNYTNGAYAARTCNGARATGAARMGNGARATH GAYTGYCARYTNAARTGYTTYGARGARYTNGTNGGNAARYTNCCNGTNTAYGTNGAYGGN CAYCARCAYATHCAYTCNCAYCCNGAYGTNGCNGARATHTTYGCNGCNGCNYTNCAYMGN CAYGGNGTNAARATHACNMGNTAYCCNATHGARATHAAYATGGAYCARAARAAYTGGYTN GARCCNAAYACNAARCARTTYYTNATGCARTGYGTNGGNTTYGCNAARCARACNAARAAR GTNYTNGAYTCNCAYGGNATHACNACNACNGAYGCNTTYGTNGGNATGTCNACNATGGGN GCNAAYATGACNGTNGAYMGNYTNCARTCNATHATHYTNGARGCNTTYAAYGAYGCNGAR AARGAYTCNACNAGYCARTCNAARGAYTTYGTNACNTGYGARYTNATGACNCAYCCNGGN TAYCCNACNAAYCCNAAYTTYGGNGGNTTYTCNTGGGGNTCNGAYGAYTTYGGNYTNTCN TCNGAYMGNGARYTNGARYTNMGNATHYTNAGYAGYAARGARATGATGGAYTTYTAYAAR GARAAYAARATHGARYTNGTNTCNCAYGARATHYTNYTNACNATHAARTCNATHCAYYTN TTYGARCARAARATGAARATGATHATHCCNCCNAGYGAYGARAAYGARGARATHGAYATH CARTAYATHATGACNMGNGAYGARGAYMGNGGNGARCCNATHCAYATGYTNAARACNGTN CCNAAYGAYGARTAYATHGGNAARATHMGNAARCARYTNCARGARGAYGCNGCNGCNMGN GARGARMGNGARAARMGNMGNMGNAARGTNYTNGGNGAYCARATGATGGCNCAYCARGCN CARGARGARGCNMGNMGNGARGARATGATGGTNAAYMGNYTNATGMGNCARTCNCARCAR GARMGNMGNATHGCNGTNCARYTNYTNCARGCNMGNCAYGARAARGARATHATHTGYCAR AAYMGNATHCARMGNGARAARYTNTAYCARGAYMGNMGNYTNAARGAYTTYGARGAYGCN YTNGAYYTNGARGCNGARATGGTNGCNYTNCAYAARGTNGARTAYGCNGARCARATHAAR GCNGAYCARAARYTNCAYGAYCARATHGCNGCNCARMGNGCNGARGARMGNTAYAARCAY CAYTAYGAYATGTGYGCNGARATGATHGTNGGNGTNGTNGAYTTYTCNTGYAARGTNGCN GARTTYMGNGARYTNACNAAYAAYYTNYTNCCNCCNAARYTNATGMGNGARTGGAARYTN YTNTTYGTNTCNGGNCARCCNYTNTTYGARCCNCARGARCARGARTCNACNGARYTNACN CCNGARCARGTNYTNGARGARGAYMGNCARCARYTNYTNGAYGARGGNGAYYTNATGGAR TAYAARATGATGAAYGGNGARTGGCARGTNCCNGARGGNGCNGARATHTCNGGNCCNCCN MGNGAYAAYCCNGTNGTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AAYTTYGAYTCNTAYGCNGARTTYYTN AGYGCNYTNAARGCNTAYCARGAYCARGARTAYTGYYTNTTYGTNAARGARAGYTGYAAR AARTTYNNNNNNGARGANNNNNNNNNNNNNMGNYTNCARTAYGARTAYGTNMGNYTNGTN TGYAARCARGGNAARMGNMGNAARGARTCNNNNTCNAARGGNYTNMGNCCNNNNCARAAR NNNNNNAARGTNGGNTGYNNNGCNNNNATHAARGTNGGNATHGCNNNNGTNAAYGGNNNN NNNGTNNNNGARATHAARNNNNNNNNNYTNNNNCAYNNNAAYCAYNNNGTNNNNNNNNNN NNNTAYAGYGTNNNNCCNGARNNNMGNNNNNNNNNNNNNNNNCCNACNGTNTCNNNNNNN GTNAARGCNAARNNNNNNNNNNNNGARYTNNNNNNNTAYGTNAARNNNNNNNNNGGNACN NNNNNNCANNNNAARGAYGTNTGGNNNNNNMGNNNNMGNYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATGCCNAGYGARGAR------ACNATHTTYCAYAARYTN GGNGARATHCCNGTNYTNAAYGARGGNTGGACNACNGCNTGGGAYTAYTAYGCNAARGTN AARGAYTAYAAYTCNYTNACNYTNYTNACNYTNAAYGTNGCNGARAGYGGNGTNAARGTN GCNGGNAARATHTCNACNCCNGTNGTNACNMGNTAYMGNCCNCARATHGAYAGYGTNAAY GARTAYGCNTGYAARAARYTNGAYGARYTNGARAAYAARTAYCCNGTNATHAARGARTCN CCNGARCARGTNAARGTNGCNTGYACNGARTAYATHGARCCNATHGTNGGNMGNGTNAAR CCNGTNGTNCARCARGTNCARGGNATHGTNGAYACNAGYAARAARCARGTNGARTGYATH AARAAYMGNGGNACNAAYATGATHTCNGAYGCNAARGAYYTNGGNATHGGNACNGTNTCN CAYGTNGTNACNGCNACNTTYGAYACNGCNCCNGGNMGNTTYGTNACNMGNACNATGGAY GGNGTNYTNGAYAARGCNGAYCARATHGTNGAYAARTAYYTNCCNGARGARGTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNGAYATGTTYATGMGNYTNTTYAARACNAAYACNAARYTNCARAAYATGTTYCAY AARTTYAARGAYATHAGYTCNGAYGAYGARYTNMGNTCNAAYGARGCNYTNGARTTYCAY GCNGCNATGGTNATGGCNACNYTNGAYGAYGCNATHACNCAYATHGAYAAYTAYGARTTY GTNCAYCARYTNYTNAGYAARGCNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GCNYTNATHAGYCAR GGNGAYGCNAAYGGNAAYACNGCNYTNCAYTGGGCNTCNTAYAARAAYAAYTTYMGNTGY GTNAARMGNYTNYTNCARMGNGGNGCNGAYGTNAAYGCNGTNGAYTTYAAYTGYGARACN CCNATHGGNTGGGCNGCNMGNAARGGNAAYYTNGAYGTNATHAARGTNYTNYTNGAYTTY AAYGCNAAYGTNGAYATHMGNAAYATHTAYGGNAAYACNGCNYTNCARAARTCNGCNGCN ATHCARGCNTCNGGNYTNAAYAAYGARAARGAYGAYACNACNATHGARYTNYTNATHMGN GCNTCNGGNCARTTYAGYYTNGCNAAYCARGARGGNGARYTNATGCCNGTNATHGTNMGN GAYAAYMGNYTNAAYGARATHYTNCAYCCNYTNGTNCAYAGYGCNMGNCCNYTNYTNGAR CARTGYMGNCAYCARATHMGNCAYAGYYTNGGNCARMGNTAYYTNCCNAGYGTNATHCCN ATGYTNCCNGTNCCNMGNCARYTNCAYGARTTYYTNYTNYTNAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GTNATGAAY TCNGCNGGNYTNTCNATHGGNYTNCARGTNATGATGCARTAYTTYATHMGNCCNGAYGAR YTNGCNGCNYTNTAYCARAARTAYCAYACNGAYTAYACNAGYGTNATHCAYMGNGTNGCN GARAGYACNGTNAARAAYYTNGCNATHAARTTYTCNATGGAYGARTAYMGNYTNGARMGN AGYAARGTNGARGCNGGNATHTTYGARCARATGAARTTYGCNYTNTCNGGNGAYTGYTGY CCNTCNTGYTGYCCNCARTGYMGNGAYTCN------GARATHAARTGYGGNGTNGAYGAY TGY---AARATGCARAAYTGYTCNCARGGNTAYCAYGTNGAYYTNMGNTAYYTNCARATG GGNCARGTNACNATHCCNGAYGAYGTNATGAAYMGNTAYATGCARCARATHATHYTNAAR ATH--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYTCNGTNYTNYTNCCNGARGTNGARTCNYTNAAYATHTCNGCNYTN GTNCARAAYYTNAAYTCNATHACNTCNGGNTCNAAYCARAAYAAYMGNCARGGNACNAAR GAYACNCARAAYGCNGAYMGNGCNCAYGGNGCNYTNGTNCCNGGNACNGGNGARATHGCN GAYGCNATHAARAGYTGGYTNGTNCARTAYTCNTCNTGYCCNGTNTAYTAYAARTGGGAR GAYYTNGGNYTNYTNAAYTGGCCNMGNTGGGTNMGNAARGGNTCNTGYTCNYTNTCNGAY CCNGAYATGTCNGAYGCNCARGCNTCNTCNTCNGARACNGARGARMGN------------ ------------GCNTGYTCNTGGCCNCCNGGNATGMGNTGYGTNGCNGCNMGNGCNMGN ATHYTNATHATHYTNMGNTGGGTNTGYMGN------------------------------ CCNYTNATHGTNYTNYTNGTNTTYATHTGYGTNTGYTGYCCNTGYGTNGCNGARTCNAAY ATGGTNGCNYTNATHGGNTCNAGYGCNGTNTGYGGNTTYATGYTNTTYGTNATHATHATH ATGATHGTNGTNTAYTTYATHTGGCCNGGNTGGTTYCARCAYATGATGMGNGAYMGNGGN AARGTNAARATGCCNAARTCNTAYTTYAARAARAARGARGARGCNAARAARMGNYTNYTN AAYGARTCNATHATHTCNCARTCNGCNTCNGTNMGNAARGARMGNYTNCCNYTNAARGAR TTYGAYMGN------------------GTNTCNTGGATHCARGAYTTYAAYCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATGGCNACNYTNYTNAAYAARGARMGNGCNCARGARATHATHGCNAAYGTNGAYAAY TTYYTNTTYGAYTGYGAYGGNGTNYTNTGGGAYGGNGARGGNCCNATHGAYGGNAGYYTN GARACNATHYTNAARYTNAARAAYYTNGGNAARAARGTNTTYTAYGTNACNAAYAAYAGY TCNMGNTCNMGNTCNGAYTAYGTNACNAARTGYCAYAAYTGGGGNTTYCCNGCNGARGAR GARGAYATHGTNTGYACNTCNTTYATHGCNGCNGARTAYYTNAARAARYTNGGNTTYAAR GGNMGNGTNTAYYTNGTNGGNAARGARGARTCNATHGGNAARGARYTNTCNYTNGTNGGN ATHTCNTAYACNGGNCCNGGNCCNGAYCCNYTNAARTCN---AARGTNGARGAYTGGTTY GARACNGAYYTNGAYCCNGARGTNACNTGYGTNYTNGTNGGNTTYGAYCCNCAYATHAGY TAYATGAARYTNYTNAARGCNTCNAGYTAYYTNAARGAYCCNAGYTGYYTNTTYATHGGN ACNAAYGARGAYGGNTGYYTNCCNTAYAARGGNMGNYTNYTNATHCCNGGNACNGGNTGY ATGATHAARCCNATHGARGCNGCNATHGARMGNGARCCNYTNATHATGGGNAARCCNGAR ACNAAYATGTTYGAYGTNYTNTGYCARYTNCAYAAYYTNGAYMGNTCNMGNACNATGATG ACNGGNGAYMGNATHGARACNGAYATHATHTTYGCNAARMGNTGYGGNATGMGNTCNYTN YTNGTNYTNTCNGGNATHGCNACNCARGCNGAYGTNGAYAGYGGNAARGCNATHTCN--- ---GAYTTYTAYACNCCNAGYYTNGCNGAYYTNGGNAARATGAAYMGNAGYMGNCARMGN GAYMGNAAYMGNGAYMGNGTNGGNCAYGGNGGNTAYGGNGGNGAYGGNYTNYTNGGNGAR GGNCCN------TCNGGNGGNAAYCCNATHATGAAYCARGGNTCNYTNAAYYTNMGNGAR TCNCARYTNGCNYTNGCNCARTCNYTNYTNCAYCARCARCARYTNGTNGCNGGNYTNGGN GGNGTNGGNGGN------------GGNGARTTYGGNGGNYTNGGNGCNYTNGCNGGNGGN ATGCAYTTYYTNCARCARCARCARCARCARATGMGNGGNATGTCNGGNGGNGGNGGNGGN AAYAAYATGGGNGGNGGNATGCAYGGNGAYMGNAARMGNATHGGNGGNCARATGMGNMGN GAYGGNGAYGGNAARCAYMGNMGNMGNGAYTCNTGGGGNMGNGGNGAYAARGAYMGNTCN ------MGNGGNAGYAAYMGNAGYGGNCARGAYMGNGAYMGNAGYMGNCCNAGYMGNTGG GARCCNGAYMGNTGY---AARGAYGAYGGNGARGAYTAYGAYCCNGCNGARCCNACNGAR GAYGAYGAY------GAYGGNAAYAARACNGAY---TCNAAYYTNTAYTGYCAYGTNTGY AAYATHTCNGTNTAYGAYGAYGAYAGYTTYCARMGNCAYYTNAAYGGNYTNMGNCAYAAR GCNMGNATGGARAGYATHYTNACNGCNCAYCARATGAARTCNACNCARYTNAARTCNMGN YTNAARGCNGARGARCAYYTNMGNAAYATHGARMGNAARGGNGGNMGNGAYCCNGAYTTY TTYTGYAARATHTGYAAYAAYGAYYTNGCNATHCCNTGGGARAARCAYMGNTAYTCNAAY ATHCAYAARCARMGNYTNYTNCARGTNMGNAARGGNTGYGGNTGGTGYAARGTNTAYGAY TTYACNAAYTTYACNGARGTNYTNGARCAYMGNGAYACNGARGARCAYAARMGNAAYGCN GARYTNTAYGGNAARAARGARGARGAYAARGAYGGNTCNMGNAGYMGNAGYAARGARAAR AARGGNGARMGNCCNMGNMGNTCNTCNYTNGAYMGNGGNMGNAARAGYAARGAYGAYGGN GAYAARAARGTNAARACNGARGARGARGARGARGAYYTNACNATHCCNGARTAYAAYGCN GAYACNCCNGTNGGNYTNACNTAYATHATHCCNGTNACNGGNTTYTTYTGYAARYTNTGY CAYAARTTYTAYAAYGARAARACNGCNAARGGNAGYCAYTGYCARAGYGARACNCAYTAY GARAARTTYCARGCNGCNATGGARGCNAARATHGCNGTNMGNGARAARGARAARGCNGAR AARGARGARMGNAARCARGAYGARGARCARGARAAR---------------GARCARGAR GCNAARGARGAYAAYTGGAARGARGGNGARGAYAARGARGARMGNGARGGNGARGAYGCN GCNGCNGARGAYGARGARGCNGARGARATGCAYGARGARTCNGCNGARGARAARGARGAR GTNGAY---------------GAYGARATGYTNGAYGARGARGARGGNGARCARYTNCAR GGNAAYTCNACNAAYGARGAYGARGAYATGYTNGARGGNAAYCARGARGGNGAYTCNTTY YTN---GARTCNGAYACNGCNGCNAGYTTYGTNTAYATGGCNGCNGARGCNGAYCAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GGNGGNTGGYTNYTNTAYAARTAYATG TGGMGNAARATHCARAARATHMGNGAYGARGARGAYAARCAYTAYYTNATHAGYATHMGN MGNCARCAYCAYTTYGAYAGYAAYCARMGNACNTGYAAYATGACNGTNYTNTCNATGGCN CCNAGYATHMGNGGNACNYTNACNAARAAYTTYGAYACNGAYGGNATHAARGARATGYTN AARTCNAAYCCNTCNAAYAARYTNGARYTNTGGGARGARYTNAARGTNGTNAGYATHACN MGNACNYTNGCNGCNGTNTAYGGNACNTGYATGYTNTCNGTNATGYTNMGNGTNCARYTN AAYATHGTNGGNGGNTAYYTNTAYYTNGAYAAYATHCAYCAYAAYAAYAARGCNAAYGTN GGNAGYGGNTCNAARMGNACNATHCCNYTNGCNGTNCARGARMGNTAYYTNTCNYTNGTN AARACNTTYATHGARCARGGNTTYATHGAYTTYATHAAYTAYYTNAARYTNGCNGTNATH AARGARATHGGNAGYGTNTCNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------YTNACNGGNGAYGGN TGGAARAARAARTGGMGNAAYATHMGNGAYACNTAYATGAARAARAARAARGAYAAYGCN AARAGYGGNCARGCNGCNACNMGNAARAARCCNTGGYTNTTYYTNAAYATGYTNACNTTY YTNGAYATHGARCCNTCNAGYACNGARAGYAAYATHCCNCCNGARTCNCARGAYGAYAGY GARGCNYTNGAYCARTCNGAYGAYGARMGNGCNAGYGTNGTNTCNYTNGGNAGYCARAGY ACNGGNTCNAGYYTNCCNTCNMGNAARCCNCCNGCNAARAARGGNGAYATHGAYCAYAAR MGNATHCARGARAARGCNGAYAARCAYYTNGCNGAYAARGAYCCNGAYGGNGAYGAYGCN TTYYTNGCNAGYTAYGCNTGYMGNATGMGNAARYTNCCNGCNCARACNAARTCNTTYATH MGNYTNATHMGNGTNCARATH--------------------------------------- ------------ATGGCNCARTAYATHCARGTNGTNGARGAYGARAGYGAYGARACNGTN GARATHCCNAGYGARAGYGAYGGNACNYTNYTNYTNACNACNYTNTCNGCNCARTTYCCN GGNTCNTGYGGNYTNAARTAYMGNAAYCCNGAYACNMGNGCNTTYMGNGGNATHMGNYTN GTNGAYGGNATHYTNCAYCCNCCNGARGGNATGTGGGGNAAYTAYCARTAYGTNGCNGTN TTYCCNAARGARAAYAARMGNAARGGNGARGAYGGNTTYGAYAAYCCNGTNGCNAARACN AARMGNYTNGAYGGNTCNAARTGYTCNGAYYTNATHGTNYTNGGNYTNCCNTGGAARAGY ACNGARGAYGAYYTNACNAARTAYTTYTCNCARTTYGGNGAYYTNGTNYTNGTNCARGTN AARMGNGAYYTNAARACNGGNATGTCNAARGGNTTYGGNTTYATHMGNTTYTCNAAYTTY GAYTCNCARGARAARTGYTGYGCNCARMGNCAYATGATHGAYGGNMGNTGGTGYGAYGTN ACNATHCCNAAYTCNAARCCNCARGGNGAYTAYAGYTAYMGNGGNMGNGCNTAYGCNTCN TAYGGNTAYGAYGAYCAYGGNTAYGAYCAYCAY------GGNTAYGAYMGNGAYGGNGGN TAYCARGARGGNAAYAAYCARATGATGAGYMGNAARGTNTTYATHGGNMGNGTNACNGAR GAYATHACNGCNGAYGAYYTNMGNAGYTAYTTYATHAARCAYGGNGARGTNGTNGAYGTN TTYGTNCCNAARCCNCAYMGNGCNTTYGCNTTYGTNTCNTTYGCNGAYGCNGAYGTNGCN CARTCNYTNTGYGGNGARGAYCAYATHATHAARGGNGCNAGYGTNCAYGTNAGYAAYGCN AAYCCNAAR---TCNYTNTCNGGNGGNAGYAGYAGYAGYAGYAGYAGYAGYCCNGGNTAY AGYCARGGNGGNTGGAAYCCNMGNAGYGGN------GGNCCNGGNCCNGTNGGNGGNAAR AAYGGNAAYGCNGARGGNGGNATGGCNGCNAAYAAYATGGGNATGAAYYTNYTNAAYTCN GCNATGYTNGCNGCNGCNCARGCNATGYTNCARAAYCCNGGNGGNTGGGGNGGNATGAAY CARGGNAGYCARGTNGGNACNGGNGGNAAYATGGGNGGNGGNGAYCAYCCNCCNACNAAY YTNCCNYTNTCNAAYCARACNGGNTTYGGNAGYATGGGNGGNGGNGGNGGNGGNGGNGGN GGNGGNGGNAAYTGGTGGGGNAAYGARAGYAAYCCNTCNTCNGGNGGNCAYTAYGGNGGN TGGGGNGGNTCNCAYGGNGGNMGNGGNAGYGGNGGNTGGAGYATGGCNGCNTCNGGNYTN AAYYTNGARAAYCCNYTNTTYMGNACNTTYATGGGNTAYGCNGCNYTNGTNYTNGTNAAR ACNATHGCNATGAGYGTNGTNACNTCNTAYTAYMGNCARACNAARAARGTNTTYGCNAAY GARGARGAYACN---------AARYTNAAYGCNTCNAARAARGGNGTNGTNATG---AAY GAYCCNGAYGTNGARMGNATHMGNMGNGCNCAYMGNAAYGAYYTNGARAAYGTNATHCCN TTYGTNYTNTTYGGNYTNYTNTAYATHGCNACNGGNCCNGAYCCNTCNTCNGCNGTNYTN CAYTTYMGNATHTTYACNGTNGCNMGNTTYYTNCAYAGYATHATHTAYATHTTYAARGTN CCNCARCCNGCNMGNGTNYTNTCNTTYYTNGTNGGNTAYGGNGTNAAYATHTCNATGGCN ATHTCNGTNATHAARCARGCNGCNTTYGGNATHTTYCARCCNCAYATHAARTAYYTNYTN TGYYTNGCNACNCCNGTNGAYATHGTNYTNYTNGGNGTNAGYTTYTCNAARACNYTNAAY GGNGGNGAYMGNGARATGCAYYTNATHCCNGAYCCNYTNTTYTCNATHCCNGCNGAYGGN GTNTAYATHACNAAYATHGTNGGNGCNGAYAAYGGNMGNGTNTTYATGGCNYTNATHTAY CARGCNAARGAYGGNTGGTTYAGYGAYAARTGYCAYAARGTNAAYCAYTCNACNAGYTCN YTNTCNTTYYTNYTNCCNTCNTTYYTNAAYTTYTCNTTYGGNGAYGAYGAYGTNYTNGTN CARATHTCNATHGAYAAYTCNMGNGGNATHYTNTTYGCNMGNACNCARMGNGGNACNATH CARGTNTTYGAYYTNGGNGARGGNATGAARAGYATGGCNMGNGTNGCNTTYCARACNCAR GCNAGYATHYTNAARTCNGCNTCNGCNATGGCNMGNACNATHGARAARTCNAAYTTYAAR TCNATHGTNTAYATHGCNGCNATHACNCARMGNGARTCNGAYAGYYTNAAYYTNGTNGCN GTNACNGARTCNGGNGTNMGNYTNTAYTTYAGYACNGCN---------YTNGCNAAYAAR MGNCCNAGYYTNYTNTCNYTNGTNCAYGTNMGNYTNCCNCCNGGNTTYTCNGCNACNTCN ACNCCNGARMGNCCNACNAAYGTNCAYACNGCNTTYTAYMGNMGNGGNACNYTNYTNYTN GTNTCNTCNCARACNCARAAYAARGAYGTNYTNTGGTCNATHAGYCCNGAYTCNTTYCCN TTYCAYAARCARYTNATGGARGCNCAYACNATHATHTCNACNGGNGGNMGNACNTGGGCN ATHGARGARGTNCCNGTNGAYCCNYTNCCNAARGCNCCNGCNCCNYTNCCNTCNTCNMGN MGNACNACNGAYCCNCCNAGYGTNGTNACNCARCAYGCNGTNCCNCCNMGNMGNTTYGTN GTNTTYAGYACNCAYGGNATHCAYATHYTNCARAARYTNMGNCCNGTNGARCARYTNAAR GCNYTNATGACNGARTGYGGNGGNCCNGAYGCNGARCARATHAARTCNTTYTTYCAYYTN CAYAARATHGAYCARGCNTGYGCNTCNTGYYTNGTNYTNGCNTGYTCNMGNGCNCCNTCN GAYCARCARGTNTCNGAYTGGGCNMGNATGGCNTTYTTYATGTAYGGNGGNGARGCNMGN TAYAGYYTNACNGGNYTNMGNCCNYTNCCNGGNATGCCNGGNCARATGTCNAGYTCNGTN YTNTAYAGYCCNGGNACNATGATGATGCARGCNACNCCNATGTCNCCNATGYTNATGTCN ACNCCNGCN------------ATGCAYYTNCCNAGYCAYATGGGNGCNGCNMGNAGYCCN GTNCARGARGTNGTNTAYTCNGGNAARCAYAAYAGYATHTAYYTNTTYYTNAGYMGNATH YTNMGNCCNTTYTGGGAYAAYCCNGTNGCNGTNGARTTYGTNTAYGGNACNAARAARAAY TCNGTNATHTAYYTNACNAGYAAYTTYACNAARGAYGAYYTNTCNATGGCNYTNGAYYTN GTNMGNGAYYTNTCNGAYTTYGTNGAYTTYAAYTCNAARTTYGAYTCNGAYATHCARTCN GAYGTNYTNGCNATHGGNMGNGGNMGNYTNGARGGNGGNYTNGAYGARCAYAGYCAYAAR MGNYTNCARATHGARGTNCARMGNATGGARAARATHTCNYTNCARCAYGCNCARGARYTN YTNCAYMGNATGGARGARGTNYTNGGNYTNTGGMGNYTNYTNYTNGAYCAYCARTTYCAY ATHYTNGCNGCNGCNATGGCNCARGAYATHCARCAYCAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNAARGAYTTYCAYATHCCNGTNACNGTNGARAARGGNMGNGCNAARGTNMGNGARATG TTYYTNAARAAYAARCAYGCNACNGAYATHMGNGCNATHGAYATGYTNGTNATHAARGGN CARATGGAYYTNGTNGARACNGCNAAYAAYTGGAARCARMGNACNCAYATHATGATGTAY TTYAARGAYACNGTNAAYCCNAARCCNACNGAYTTYYTNTCNAARTTYTAYGARGGNCAR GAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGCAYGGN AGYGAYAAYYTNTAYAARMGNATGGCNGTNCARCCNYTNTAYMGNGARACNCARATHGAY CCNGAYYTNGARCAYAARGCNAARAARGTNTCNGARAARATGTCNGARACNGTNAAYATG ATHGCNAAYGARCCNTCNYTNGCNTTYTTYMGNATHCARGARCAYGTNMGNAARACNYTN CCNCARYTNGTNGAYACNAARCAYGAYGTNGARGAYGTNCARGCNATGGTNCARGGNGCN TGYTTYGAYGCNGARTAYGCNACNAAYGCNGTNAARGCNATGCARTCNAGYGCNATHCAY TTYCARAAYATHCARGAYYTNYTNAARAAYGCNATGTTYATGAARCARCARATHTCNTAY GTNGARGCNMGNMGNMGNCARGGNMGNGTNAGYCCNGTNCARGGNGARMGN--------- ------------------------------GGNGCNGGNTTYCAYTAYGGNGTNAAYACN TGYGARGCNTGYAARGGNTTYTTYCAYMGNAGYYTNMGNTAYCAYGARCARTAYAARTGY AAYAAYGGNGGNAAYTGYTCNATHYTNCAYGGNAARGGNAARATHTGYCARTGGTGYMGN TAYCARAARTGYYTNGARGTNGGNATGTCNAARATGGCNATHAARACNGGNMGNTAYACN TCNGCNAARAARACNGARGAYATHYTNGARGTNAARTGGYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AGYTCNMGNTTYGCNTGYYTNAARATH GARGAYGAYGARGARGARCARAARACNGCNACNAARACNACNCCNGTN------ACNAAY GCNAAYGCNGCNAARAARAARAAYAARAARAARAARGARGCNAARGARAARGARGARYTN AARCAYYTNGCNTTYGGN---------------------AARYTNCCNCCNAAYAARGGN AARGARGGNGGNMGNAARGGNGARMGNATHGTNTGGGAYAAYTGGGTNGARCAYGAYGCN GGNYTNATGGARGAYCARTTYAARACNGAYATHGARAARGCNYTNYTNGCNAGYAARYTN GAYYTNGARAARCARCARCARGAYMGNAARCARMGNCARGARMGNATHGAYGCNGGNYTN GARGTNCCNAGYACNMGNGARGGNMGNAARAARAARAARCARAARGAYAARCCNCARCCN ATGTCNYTNGARCARTTYAAYAAYYTNCCNAARGGNAARCCNCCNGCNGAYTCNGAYGAY TCNGAYGGNAARGTNAAYGAYATHGTNYTNCCNCCNCCNGCNAAYCAYMGNGTNCCNCCN ACNCARCARGAYCCNGCNTTYTTYAAYTCNGTNGARAAYGARGCNGARCAYATHGTNYTN CAYGARAARGTNCARGARAAYTAYMGNAARCARTAYACNACNGAYAAYGCNGTNATHGCN AARTTYMGNGAYGAYYTNGARAARAARGAYGARMGNATHTCNGARYTNTCNGGNCARGTN GGNACNATGGARGGNGARYTNAARCARGTNAARAARMGNAAYAARCARYTNTGYTTYATH YTNGCNCARGGNGARATGAARGAYAARGCNCARGTNYTNYTNCARGTNGARGARYTNACN AARGTNAARGAYGARYTNACNGARCARGTNATGTCNYTNACNGCNTCNYTNGARAARGAR AARTCNAARAAYCAYGGNATGAARGCNGARYTNGTNAARYTNAARGCNAAYMGNCARGGN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATHAARGCNGARAARGGNATHGARGCNGTNAGYGTNGGNACNATHYTNTCN GAYTAYCARMGNGTNMGNGTNGARAAYGTNTGYCARMGNYTNGCNYTNACNGTNYTNTCN TTYYTNTGGMGNMGNGAYCARGARGARYTNYTNAARGARATGATHGCNTGYGAYGTNAAR GCNATHATHATHAARGTNGCNGCNATGGGNYTNTCNCCNAARAARCAYYTNGGNATGGAR YTNTCNGARATHYTNCCNCAYATGYTNAARATGAARGARGARTTYGGNYTNAAYGTNTGY GGNGARGGNGGNGARTAYGARACNTTYGTNTTYGAYTGYCCNYTNTTYMGNAARTCNATH GTNATHGARGARAARGARCAYATHAAYCAYTCNAAYGAYGCNTTYGCNCCNGTNGCNTAY YTNAAYYTNAAYMGNTGYAGYYTNCARGTNAARCARTGGAAYGARAGYCARACNYTNCAR GAYAARGTNYTNGCNYTNCCNATHACNACNAGYTCNAARTGGYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CCNATGGTNCCNACNAGYGCNGCNCAYYTNATHYTNGAYTAYGCNCARACNCARMGNAAY CCNATHCAY---AARGGNCCNCCNYTNGCNTGGACNACNTCNGAYGCNAARCAYMGNTCN TTYGTNMGNGCNGGNYTNAAYTAYTCNGCNGGNCAYATHGTNGTNYTNGARCCNGGNACN TAYCAYGTNTAYAGYCAYATGACNYTNAGYACNYTNAARAGYGARAAYAARAARAARAGY ATHGTNCAYTCNATHCARMGNMGNCCNGCNAGYTAYGGNAARGCNYTNYTNYTNGCNCAR GTNACNATGCAYGAYGGNGARGTNAARACNACNAAYYTNGARGGNTCNTTYGARYTNCAR ATGGGNGAYMGNYTNTTYGTNTAYGTNAGYTAYCCNTCNTAYYTNAARGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TCNACNCARYTNGAYGAYTTYCARCARAARYTNAARGAY GTNACNMGNGARYTNGARAARACNTCNCAYGARYTNMGNAAYACNCARYTNACNYTNACN GARAGYGARMGNAARAARGAYGARTTYAARGGNMGNGCNCARGARACNGTNMGNCARTGG AARGTNAARGTNAARCARYTNGARMGNGAYYTNGAYMGNCARAARCAYGGNACNGGNCAR ATGATHGCNMGNAAYGARCARYTNGTNAARGARATGGARGGNCARAARCAYCAYGGNACN TAYAGYCARYTNCARGTNGARGGNYTNAARMGNGARYTNTCNGAYGCNYTNGCNGTNMGN GCNGCNCARGAYGARCARATHMGNYTNAARGAYATHGARGTNAAYGARYTNAARTCNGTN MGNATGGAYYTNGARMGNGARTAYMGNGAYACNCAYACNATHGCNGARAARYTNGCNGCN CAYYTNYTNGCNCARGGNCARTCNCAYTGYYTNCARGAYGARYTNAARGAYYTNAGYTCN GTNAARGCNGGNYTNGCNGCNCARYTNGCNGARATGATGGCNAARAAYCAYGAYYTNAAR CARGCNGTNGTNGARTAYCARCAYMGNGARAARGCNGCNAARGARGARGCNGAYATGTAY AARAARCARYTNTAYCARGARMGNAAYGGNYTNAGYAARAAYTGYGARTCNYTNAARCAR GARYTNAGYGARGCNAARGTNMGNGARGCNCAYACNATGCARGARGTNAAYMGNAARTTY MGNGCNAGYAAYGCNAARACNGAYGCNTCNATHCARGCNYTNAARYTNGARYTNTCNGAR GARAARTCNAAYGTNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TGGGGN------GTNGAYMGNYTNATHACNAGYTCNGCN TGGCARAARATGAARGCNATHTCNGCNAAYGARGGNYTNATHGCNTGYGCNTAYGARMGN AARTTYCARGARTGGAGYMGNYTNTAYCARATGTCNAARTTYYTNYTNTTYGARCCNTCN GCNGGNYTNTAYGGNTGYCCNYTNGCNATGACNAAYGGNGCNGCNMGNACNATGGARATG AGYGAYGARGAYMGNGARATHGAYATHGARAGYGAYGCNGAYGAYGARGARGGNCCNCAR ACNTAYAGYTCN---GAYGAYAARMGNGCNCAYCAYAAYGCNYTNGARMGNAARMGNMGN GAYCAYATHAARGAYAGYTTYCAYAGYYTNMGNGAYTGYGTNCCNCARGAYGAYCARAAR ------ACNAAYACNTCNAGYAARACNTCNMGNGCNCARATHYTNMGNCARGCNTCNGAR TAYATHATHMGNATGMGNGAYAARACNACNCARAAYGAYCAYCAYATHCARATHYTNAAR CARCARAAYGAYGAYYTNCARGCNCAR--------------------------------- ------------------------------------------------ATHAARGCNYTN MGNTCNCAR------------------------------------------TCNGGNGGN ------------------------------AARGTNGTNYTNAGY--------------- ---------TCNAGYTAYYTN--------------------------------------- ---------------------------------TTYCARGTNACNGGNYTNGGNAAYCAY GGNTAYCCNGAYACNMGNCAYAGYATHGGNATGAARGCNGTNGAYGGNYTNGCNGCNMGN YTNMGNGTNCARTGGAARACNAGYCARMGNGARTAYGCNGGNGCNATHGCNMGNACNGTN ATH--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GAYYTNGGNCCNTAYNNNNNNGAYGCNTTY CCNAARCARTCNGARTAYMGNMGNCARTTYCARCARTGGAARCCNYTNGCNTCNAGYACN GAYYTNGCNYTNAAYYTNGAYGAYAARCARGARGARACNCARGCNAARAARATHAAYGTN ---AARMGNAGYAARAGYGCNGGNGCNGTNYTNMGNAARCARCCNGCNTCNGAY------ AAYCARGARCARGAYGAYGGNATHGARGARGTNAARGARAARYTNAARAARACNTTYGGN AARTTYMGNMGNYTNGGNACNGARTAYGGNGCNAAYTTYAARTCNCCNGCNCARTAYAAY TAYACNMGNGGNACNTGGAARGGNGCNAAYCCNCAYCAYYTNACNCCN---------GCN ACNGAYGCNAAYAAYAAYCARAAYAAYAGYAAYAAYAAYAAYGCNGAYGARAARGCNCCN YTNTCNAAYTGGTTYGCNGARGTNATHGARYTNMGNMGNMGNGCNGARGARTAYMGNAAR MGNGCNCARGGNACNCAYTTYTCNMGNGARCAYYTNGTNCARYTNATGGCNMGNCARAAY CARTGYTGGGAYYTNGAYTCNGAYGCNTCNGCNACNGTNAARGCNYTNGAYYTNGGNATG CCNATGYTNAARCARCARTGGAARAGYCARCCNAARGCNTGYATHGCNGGNAARCCNGTN GTNGGNAAY---TCNAAYATHGCNATHGARGGNGGNTCNCCNGTNATGTCNGAYGTNGAY GAYGTNGARGARCARMGNAARGARGGNAARGCNAAYAARGGNMGNMGN------------ ---CCNAAYCAYMGNAGYMGNAARATGGCNTTYYTNGARGARCARAARGARTCNGTNGCN MGNCARCAYAARAAYATHGARGARCARGAYAARATGGARGCNGAYAGYGAYGAYGAYGAY YTNGAY---------------------GARGGNMGNMGNCCNACNCCN---GTNYTNCAR ACNAARACNAARGTNCARMGNCAYCAYYTNGAYYTNACNACNCCNTCNGTNGGNGGNGCN YTNYTNACNTGYCCNCCNTCNAARGAYAAYAARATHATHATHACNTCNMGNTCNGGNGAY AGYTAYGTNACNGCNTCNGAYGAYGTNCARCCNGTNAARTCNTCNAARAARACNAAYATG GARGARYTNATGACNATGCCNATHYTNGGNCAYCCNTCNAGYGAYACNCAYGCNYTNMGN GAYGAYTAYGCNAGYGARGAYMGNCCNYTNGARACNCARTAYGTNGCNACNCCNTTYAAR TCNTTYAAYGAYGARGAYAARGARAAYAARAAYGCNCARAARGCNACNCCNGARGGNCAR AARYTNAGYMGNYTNCCNCCNGTNATGGARAGYTAYGGNAARACNTTYACNAARCCNTCN GTNAGYYTNACNCARGAYGAY---------------YTNAAYAGYAGYGAYGAYGAYGTN ATGTCNGTNTCNATGMGNTCNGTNACNTCNAGYAGYTCNYTNGCNTCNGAYGTNTAYGAR MGNGCNMGNMGNMGNCAR---GARTTYTGGGGNAARAARAAYTTYYTNTAYTTYGCNTTY GGNAGYAAYATGYTNMGNGARMGNATHYTNATHAARAAYCCNACNGCNGARYTNGTNGGN GTNGGNACNYTNAARAAYTTYGARYTNTAYTTYGAYAGYATHAARCARATHGGNAAYGGN TAYTAYGGNGCNGCNGCNAGYATHMGNGARGCNTCNGAYAARCAYGTNTGYGGNGTNGTN TGGAARATHGCNCARGAYCARATHGARAAYYTNGAYMGNCARGARATGTGYTAYMGNGCN ATHAAYATHCCNGTNGARYTNACNGAYGGNCAYACNGARACNTGYMGNACNTAYCARATH AAYATGGARACN---ACNGGNGARGARYTNCCNCAYCCNACNTAYAARAARGTNATHGTN GAYGGNGCNAARCARAAYGGNGTNCCNGARGARTAYGTNMGNTAYYTNGARAAYATHGAR GAYAAYGGNAAYCARGARATHCCNCCNGGNTAYAARACNGTNYTNAARAGYNNNTCNGGN AAYCARCARTGGYTNCAYCCNGCNGARGCNYTNYTNMGNGGNCAYATHYTNTAYACNGTN AARTTYYTNGGNGARTGYGCNGTNGAYCARCCNAARGGNACNGAYGTNGTNAARAGYGCN ATHACNAARACNAARTTYAAYAARCAYATHAARMGNGCNGARGGNCARAARYTNCCNAAR GTNGARYTNACNATHTCNGCNGAYGCNGTNAARGTNYTNGARCCNAARACNAARATHATH YTNCAYCARTAYCCNYTNCAYMGNATHTCNTAYTGYGCNGAYGAYAARTCNGAYAARMGN ATGTTYACNTTYATHGGNAARGCNGCNACNAAYAAYGAYCAYTTYTGYTAYGTNTTYGAY AGYGARAARTGYGCNGARGARATHACNYTNACNATHGGNCARGCNTTYGAYYTNGCNTAY AARMGNTTYATHGARACNTCNACNGGNAAYTCNGAYGTNAARAARCAYATHYTNAAYYTN CARAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TCNTCNCCNTTYTCNCCN---ACNAARGGNATHAARMGN ACNCAYGTNGARATGGARAGYTCNAGYGARGCNTCNTCNCCNGCNAARGCNTCNCCNCAR AARAAYAARAARMGNTGYTTYACNTGYAGYTGYAARYTNGARYTNGCNCARMGNACNATH GGNAARTGYMGNTGYGAYMGNATHTTYTGYGCNATGCAYMGNYTNCCNGARYTNCAYGGN TGYAARTTYAAYCAYAARGARGAYGGNMGNMGNGARGCNMGNGARAARATGGTNAARCCN ACNMGNCAYATGGGNACNTCNTTYMGNMGNGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TCNGGNGAYCAYAARCAR AARATHYTNGTNAAYGTNACNYTNGARGGNYTNAARATHYTNGAYGCNACNAGY------ GTNYTNCAYACNCAYCCNGTNCAYMGNATHTCNTTYATHTCNMGNGAYGTNACNGAYAAY MGNGCNTTYGGNTAYATHTTYGGNGAYGAYGGNGGNAARCAYAARYTNTTYGCNATHAAR ACNGCNGCNGCNGCNAARCARYTNGTNYTNGCNYTNMGNGAYYTNTTYCARGTNGTNTAY GCNATGAARAARCARGARATGGAYGARGCNAARYTNAARATHGAY--------------- ------GGNAAYATGGARAAYTCNTCNACNTCNGGNCCNGGNCCNACNTCNMGNGARGCN CARGAYCCNTCNAAYCARAAYGCNGAYGGNGAYGGNATHTAYCARGTNCCNCCNAAYAAY GCNCCNGTNGAYACNAGYCARGARGARCARGTNGCNAAYYTNYTNGAYYTNGARGAYCAR GCNGARCAYATHYTNAARGAYATHGARCARATHAARAAYYTNGARTTYGAYTCNTCNGAR GTNATGTCNACNACNGCNYTNATHYTNGARAARMGNCCNGAYAAYYTNCCNACNAARAGY CCNGARGARGARGARMGNCAYMGNCARGARTAYGTNCARATGGTNGARGCNGCNAARAAR AARGARCARAARGAYYTNAARYTNMGNAARAARYTNCARCARCARMGNAARYTNGARGAY AARYTNYTNTCNTTYGCNAARATHTGGACNYTNGARATHYTNCCNAAYTGGGARTAYATG MGNCARAGYAARAARGCNMGNGARYTNTGGTGGYTNGGNYTNACNCCNAAYGTNMGNGGN ---------GTNAARATGTCNGTNATGACNTGYYTNGCNTGYAAYGTNGGNTTYGARGAY GCNGGNYTNGGNMGNATHCAYTAYAARACNGARTGGCAYMGNTAYAAYYTNAARMGNAAR GTNGCNAAYYTNGCNCCNGTNACNYTNGARAARTTYGARGARMGNCARTCNATHCARGAR AAR------AAR---GARTCNTCNACNCARCCNGARGGNTGYAAYTGYAARCCNTGYAAY AARTCNTTYAGYTGYGCNAAYGCNTAYGARAAYCAYYTNCARTCNAARAARCAYAARGAR ACNGTNTCNGGNTCNTCNAGYCARCARAARGTNAARACNMGNACNGCNACNAARAARGAR CARAGYTCNTCNTCNACNAARACNGTNACNGARAAYGTNGTNGARGARGGNGAYGARGAR GARGAYGAYGARTCNGAYGCNGARTCNTGGGAYAGYTAYGAYGGNAAYTCNYTNGGNATH GARGARTGYYTNTTYTGYTCNTTYATHAGYTCNTCNATHGARGAYAAYATHAARCAYATG ACNATHCAYCAYGGNTTYTTYYTNCCNGAYGCNGARTAYATHAGYGAYYTNGARGCNYTN ATHACNTAYYTNGGNGARAARGTNGGNGCNGGNCAYGTNTGYYTNTGGTGYAAYGARAAR GGNAARAARTTYCAYAAYTCNTGYGAYGTNCARAARCAYATGGTNGAYAARGGNCAYTGY AARYTNYTNCAYGARGGNGARGTNYTNTAYGARTAYGCNGAYTTYTAYAAYTAYACNAAR AGYTAYCCN------GAYTGYGGNAAYCCNGARGTNGAYCCNGAY---GARGCNATHGAY ATHATGGARYTNGAYACNGAYGGNTTYTCNYTNGTNYTNCCNTCNGGNGCNACNATHGGN CAYMGNTCNYTNGTNMGNTAYTAYAARCARAAYATGGTNCCNCAYTGYMGNGARGGNACN GARAARACNYTNCCNAARATGYTNGCNCAYTAYAARGCNYTNGGNTGGACNGGNTCNACN GGNCCNCARGTNGARCARMGNGCNAARGAYYTNCARGTNGTNCARMGNATHMGNAARAAR CAYTTYATGMGNYTNGGNTGYAARGCNAAYAAYYTNMGNCAYCAYTAYMGNGAYCARAAY GAYMGNTCNAARTCNGCNYTNTCNATHCARCARCCNCARGCNYTNGARTCNYTNGCNTCN YTNGCNATGMGNAAYAARTCNGTNYTNYTNAGYTGYYTNTTYATGGARGGNATHAARAAR TTYGCNCARGTNYTNCARCAYGARTTYAGYGTNCAYYTNATGAARAGYYTNTAYCCNYTN GTNGARAAYYTNGGNCAYGARAAYGTNCCNATHAGYAGYAAYGCNTAYYTNACNYTNACN CARATHTGYTCNGCNTGYGGNTGYAGYTCNATHGAYMGNYTNATHCARAAYAAYGCNGAY TAYYTNGTNAAYAGYGTNTCNYTNMGNYTNMGNCAYYTNGARCARAAYMGNMGNACNCCN MGNYTNYTNAGYGTNATGYTNMGNTAYTGYTCNMGNGAYATHYTNCCNYTNATHGAYCAY AGYATHACNCARATHYTNGAYACNYTNGAYGAYCAYTAYACNGARGAYYTNGTNYTNTTY ATGCCNGTNYTNYTNGARATGACNYTNGCNATHGGNMGNTGGTTYCCNCCNGCNYTNCCN GCNATGTCNTCNGCNMGNCCNTGYGAYGAYTCNATGAARMGNGAYCCNGARTCNGTNGTN GTNTTYGCNGARAAYTTYYTNGARCARMGNMGNATHGCN------------GAYGGNAAY GTNYTNGAYGGNGAYGARGGNCARGAYGTNGARAGYACNYTNAARGAYATHGARMGNGAY ATGGARGCNYTNATGGARGARAARMGNAARAARGARGGNMGNGAYGARGAYGARYTNGAR GTNAARAGYGAR---------GARCAYGGNGAYMGNGCNCCNTGYCCNAARCAYATHCAR GTNGTNATHGAYATHTTYCARMGNGTNAARCAYYTNYTNTCNTCNCAYGAYGCNMGNGTN MGNGTNCARGCNYTNGARGTNATGACNCARGGNTGYACNGAYYTNAARGAYTAYCARMGN GARYTNYTNCCNCARGTNCAYCARYTNTGGCCNGCNTTYTTYCCNMGNTTYGAYAGYGAR GARAARTTYGTNATHATHAARGCNYTNAAYACNYTNGARGTNATGGCNGAYGCNTGYGGN AGYTTYYTNTGYCARMGNGTNATGMGNGAYGTNATGCCNGGNYTNGARCARTTYATGGAY YTNCARGCNAGYATHAGYMGNGAYAGYGGNCARGCNTAYCARTAYACNACNAAYTTYAAR YTNCARCARACNGTNYTNAGYATHGTNGGNCCNYTNGCNGTNAARATGGARYTNCARGCN AAYCAYYTNAARCAYYTNGTNTGGATGTGYYTNCCNTAYYTNTGYGAYMGNCARCCNGAY CARYTNCARAARACNTGYYTNGARGCNTTYTCNTCNTTYGTNMGNYTNGAYGCNGAYACN GTNTGGYTNATHYTNGTNCARACNTTYTGYCCNGGNAARYTNACNCCNCCNGGNCCNGAY TTY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CCNCCNGAYCARAGYCCNCAYYTNCCNATGCCNATHCCNTCNTCNGCNTCNGGNATGATG GCNGAYMGNYTNCCNAGYTTYAGYACNATHGTNTCNAGY------AGYAGYGAYYTNGCN AARAGYAGYCARGCNYTNTAYTCNAGYATHGGNACNTCNYTNTCNGCNCARCARCAYGCN TTYCARCCNTCNGGNMGNAGYTCNYTNCARTCNCAYTTYGAYTCNTCNTTYCARGAYCAR GTNGCNGCNAARAGYTAYAGYAARTCNTCNCCNYTNGGNACNACNTCNCCNGGNATGAGY AGYAAYTTYAGYAAYYTNCCNCAYTCNTCNGTNATGCARGGNTCNTCNCAYAAYGGNACN AAYCAYYTNCCNTCNYTNTCNCCNMGNTCNTAYAARGARGAYTCNGCNTCNCARCARGCN TAYATHGCNTCNATGCAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARAARGGNACN ATGAARTCNAARTCNAARGARAARMGNCCNAARATHGARATHATGTCNCCNTCNGARYTN CCNGCNGCNGCNGTNAARCCNAGYCCN---------GCNGTNGCNAGYYTNNNNNNNAAR ATHACNTCNGGNTCNAGYCCNTCNAGYGCNCAYGTNGCNYTNCARTCNCCNTCNGGNGAR GCNGTNAARGCNAARAAR---AARCARAARAARGTNAARTCNCCNGAYGGNGAR------ ---------------------GAYATHAARGGNATHYTNGGNYTNGCNGGNAAYGAYGAY ------------ATHTCNCCNGCNAARAARAARAARGTNTCNAARAARAARGARAARYTN ATHCARGAYGCNATHAGYGCNGCNATHCARATGCCNAAYYTNGCNGCNYTNGTNGCNTCN ---GGNAAYCCN---GCNGCNCARGCNCAYGGNGAYTCNTCNCCNYTN---------CCN CARAARGTNCAYAARAARAARGTNAARTCNTCNCCNGTNGCNCCNAGYGAYTCNCCNATG GAYCAYGARATH---GGNGARAAYTCNTTYGARGTNGARGGNGAR------GARYTNACN YTNGTNATHGCNGARACNGARGAYAARAARAARAARGTNYTNGGNAARAARAARGGNCCN AARGARAARGGNACNGGNGARGCNACNAARGGNGARAARCCN---MGNAARATHCCNAAR MGNGCNCCNACNGCNTAYATGYTNTTYTGYAAYACNCAYMGNCCNAGYATHGTNGCNGAR AAYCCNGGNATHGARTTYGCNGGNATHAGYMGNAARYTNGGNGARYTNTGGCARACNCAR TCNAAYAARCARAARYTNGCNTGGMGNMGNAARGCNCARMGNMGNYTNAARAARTCNAAY YTNATHTCNACNGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARYTNTGYGCNTAYGCNGTNCARTCNGARYTNGGNGAYTAYGAYCCNMGNGTNAAY ACNTCNGGNTAYATHTCNGARTTYTGYTTYATHCCNAAYCARACNGARGAYYTNGARGCN MGNATHGCNGCNATGCAYMGNMGNTGYGTNGGNGCNACNCCNYTNATGACNGARCAYMGN TTYYTNGARAARTCNAARTGGYTNGARATGTAYGGNGTNGAYYTNCAYCCNGTNCARGGN GARAGYAAYGTNGARTAYTTYYTNGGNYTNACNCCNACNGGNGTNGTNGTNTAYAARCAY AARTCNAARGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GGNTAYGGNCARCCNGGNGCNGCN------------------TAYCCNCARCAR CCNTAYCARATGGCNGGN------CARCARCCN---CARCARGTNGTNTAYGTNMGNGAR GARMGNCARAARGAY------GAYAAYGCNGCNGARACNTGYTGYATHATHGGNYTNTGY AGYGCNYTNYTNTGYTGYTGYYTNATGGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARTAYMGNCAYCAYTCNGTNGAYGAYGAYTAYTAYGGNTAYCCNTAY GGNTAYGGNTAYTAYCCNTCNAAYTAYAAYTAYGARAARTAYGGNATGCARTAYAGYTCN CARCCNATGYTNGGNMGNTCNATHAGYMGNGAYGGNAARYTNTTYGARCCNTAYTAYCAR CARGGNACN--------------------------------------------------- ---CCNAARMGN------CAYTCNGAYMGNGAYTAYCAYMGNGAYAGYMGNAAYGGNGAY GCNAARGAYAARGAYMGNGGNTCNGARAARGAYMGNCCNTAYAGYGAYGAYTTYCCNTCN YTNAAYGGNTCNGGNGARGGNCCNGCNGAYACNAARACNAARCCNGGNTCNGGNGTNTGG GARAAYCCNCCNAAR---TCN---AGYTGGACNGARGARTCNACNGAYYTNYTNAARAGY TCNTCNCCNGGNATHTAYAARGCNYTNGTNCCNAGYAARAAYGTNCARGGNAARAARACN GGNAARGARGCNGCNAARGGNAAYGCNAAYGTNMGNGAYYTNTCNCCNYTNAGYCCNTCN TAYAARCCNAAYTAYAARGAYGCNACNMGNCARAGYCCNACNACNGAYYTNGCNATHGTN ACNCARCCNAARAARYTNGGNGAYAARAARAGYGAYTTYYTNMGNGCNYTNMGNAAYGAR ACNACNGTNMGNAAYGGNGARATHTTYCARAAYCARAAYCARAAYAAYGTNGARAARAAR CARGAYYTNAARGGNGAYGGNCAYAGYCCNATGAAYGARGARAGYCCNAGYTAYACNCAY YTNAAYGGNGARAGYCARGTNGAYTCNAAYAARAAY---YTNYTNAAYGGNAARACNGGN GAYAGYYTNGAYMGNTAYATHAAYGGNGAYCARGGNATGAAYGGNGARGCNYTNATHGAY GAYGTNGAYCAYATHTCNYTNTCNGGNGARGARGARGARAARMGNYTNYTNYTNTCNATG GGNTGGGTNGARGARGAYAAYACNGARTAYGTNATHACNGARGAYGARATHMGNGARTTY CARAAYYTNYTNCARAAYCAYTGYCAYGGNCARAARAAYAAYCARAARTCNTTYMGNAGY TCNYTNAAYMGNAARTTYACNGCN------AAYGGN---ATGYTNAAYGGNATHCCNTCN GARGARGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYACNGCNTTYGGNCARGTNAARYTN GGNGARYTNGGNGCNTGGGCNGGNMGNMGNAAYAARGGNCCNGARGCNATHTGGAGYACN ATHCAYMGNGGNTAYTGGMGNTGGGCNACNAARAAYYTNCAYGTNMGNCARTCNGGNTTY GTNCCNTTYGGNCARGCNGCNATGGTNYTNTCNATHACNTTYTTYGTNATHYTNCAYAAR GARMGNAGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATHAARMGNAAYGARGCN GARATHNNNTCNTGYMGNGAYGAYATHMGNAGYAARGTNGARGGNATHGARAARYTNGAR MGNMGNGTNTAYGARYTNAARGTNGARATGAAYCARTCNGAYTCNCAYTGYAARCARYTN GAYGCNACNATHACNGAYYTNAARTCNGAYGGNGARGTNYTNMGNAARGARYTNAARGAR TCNMGNACNCARTAYAARGAYTGYGCNCARGARYTNGCNCAYCAYGARGARAARYTNAGY YTNATGGARAAYAGYYTNCARTCNACNCARGAYCARYTNAGYCARMGNGTNACNGARTTY GTNAARCAYGARCARAAYACNMGNAARYTNCARGCNGARYTNMGNACNGTNAARGAYGGN GCNAAYGGNTAYGARGARGARATHGARGARCARAARGGNATHATHGAYAARYTNMGNAAR GAYYTNGTNATGTCNAARGARGARTGYCAYTCNTCNGTNCARGARGGNATHGCNTAYAAR CARCARGCNCAYAARAAYGCNYTNGARYTNTCNGGNAGYAARGARCARGARAARATGYTN TCNGGNCARGTNGARCARCARGARCARATHYTNGARCARYTNCARGTNGARYTNMGNGCN GARMGNGARMGNCAYGGNGARACNGTNMGNCARYTNAGYAGYAGYAARAARGTNGGNYTN GAYYTNCARTCNGAYYTNGARGAYGTNCARAARCARGCNMGNGARYTNCARGARAARGTN MGNTCNMGNGARGARCARGCNTCNCAYYTNMGNCAYGARYTNGAYATGATHCARCARAAR AAYMGNGAYGTNCAYGARGTNYTNGCNGARAARGARGGNCARYTNMGNYTNGCNAGYATG AAYYTNCARACNGCNCARAARCARTTYAARCAYCAYATHCARGARATHGCNMGNTAYGAR GAYACNYTNGCNCARATHCARACNGAYCAYGARAARYTNCARGARCARTAYMGNAARGTN AAYYTNAAYYTNATGGARGCNGAYAGYAARGTNCAYGARYTNAARGTNCARYTNACNACN GTNCAYGGNAAYCAYAARGARGCNATGGAYCARYTNACNGAYAARTCNMGNYTNYTNGCN ACNATHAARACNGARGCNGCNAARYTNGCNCARCARAAYAAYACNATGAARGARGARYTN ATGTTYTAYGAYGARAARGCNMGNMGNYTNCARACNGARYTNMGNAARTCNCARGARATH AAYAARGCNACNCARGARGARYTNCARCAYTTYGARGARMGNTAYACNAGYYTNCARGTN GAYYTNGTNTCNAAYCAYGARAARCARAARYTNTCNYTNCARGARYTNTCNGCNAARGAR GARGARYTNGTNGTNGTNAARGTNGARYTNAGYTCNATHCAYGARAARTAYAARATHGTN AAYGAYGARGCNACNAARYTNCAYAGYGARYTNGAYYTNATGAARCARAAYTAYMGNAGY GCNAAYGARGARATHGGNGGNYTNMGNGTNGCNYTNGARGARTCNMGNGCNAAYGGNGAY MGNYTNCAYMGNGARAGYGAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AGYCARTTYTAYAGYYTNGARAAYGGNAARGGN GAYYTNGTNGTNMGNAARMGNTCNMGNGGNCAYMGNGAYMGNYTNCAYCARYTNMGNCAR GGNAAYMGNMGNTTYACNATHCARGGNYTNGAY---------CAYCCN------CCNGCN GGNYTNTAYGAYGAYAGYYTNTCNGARCCNAGYGAYTCNTCNAARGGNGAYGTNCCNGAR GAYYTNYTNTCNGTNTAYAARAAYATGACNAARGARGARYTNYTNMGNGTNGTNATHCAR ACNAARGCNCARATGATHMGNAARGAYCAYTAYATHAARGAYYTNGARAARTAYATHGAY GAYYTNYTNGTNMGNGTNATGGARACNACNCCNMGNYTNYTNAGYMGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYACNATGTCNCARAGYYTNGTNGARMGNGTNTCNYTNYTN CARMGNGARAARGAYYTNATHTAYMGNAARATHCARGARGTN---CARCARGARGARYTN TCNMGNCARMGNCARCAR---------CAYMGNAAYATHCAYTCNCARMGNAARGAYGAY YTNYTNCARACNYTNACNGARYTNAARGCNCARYTNGARGARCARAGY------------ ------------------------AARCARGGNATHYTNAARAAYTCNACNAGYATHGAY CAYAGYAARAARGARYTNGARTGGGAYGARATGAAYATHYTNGCNACNCAYCAYCCNCCN GAYAARGAYTAYGGNTTYATGAARGTNGAYGARCCNCCNACNCCNTAYAAYMGNGCNGCN ATHTCNGAYGGNGARGAYGAY---AGYCARGCNGAYMGNAARGGNAGYATHGGNGARTCN TCNCAYYTNGAYCCNGCNGTNYTNGCNGARMGNYTNGARCARGGNGGNGARAGYCAYMGN ACNYTNAAYYTNGAYGAYGAYGAYGAYGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AAYTCNAGYMGNTAYAARACNGARYTNTGYMGN CCNTTYGARGARAGYGGNTCNTGYAARTAYGGNGAYAARTGYCARTTYGCNCAYGGNATH CARGARYTNMGNAAYYTNGCNMGNCAYCCNAARTAYAARACNGARYTNTGYMGNACNTTY CAYACNACNGGNTTYTGYCCNTAYGGNCCNMGNTGYCAYTTYATHCAYGGNGAYGAY--- ------AARGCNGARCCNTCNGCNAAR------AAYAGYMGNGARAARGGNAARGGNAGY CCN---TCNYTNAGYGGNAGYAGYAGYCCNTCNYTNAGYCCNTCNGGNAGYGAY---GAY CAYAGYTAYTTYCARTAYMGNTCNGAYACNAAYCCNMGNYTNGGNGGNGARAAYMGNCCN AAYAAYAAY------TCNYTNACNGTNAAYATHAAY------------TAYAAYAAYGTN GAYATHCARTCNYTNGARCARCAR---TTYAAYTCNGCNYTNAAYTTYAARAAYAAYTGY YTNAAYGARTCNGCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNMGNMGNATHGGNAARACNTCNGTNTCNCCNGAR MGNTTYGARAARAAYATHATHAARTTYTGYCAYCAYTTYTCNGARTTYGAYGCNTGGGAR ATHGARAGYTAYGGNTAYAARCAYGCNAAYGTNAARACNAARATHMGNGTNYTNAARAAY YTNYTNGARTGYCARTTYGAYTAYAAYYTNAARTTYAARGARAARGTNAAYGARAGYAGY GCNGARGARATGMGNTTYYTNCCNATHGGNMGNGAYAARGARGGNCARGCNTAYTGGTAY TTYATGGAYAARGAYYTNAAYYTNATGATHTAYAARGARGARCARGAYGAYGARGAYGCN GAYACNTGGCARYTNGTNTGYAGYGAYMGNCARCARYTNGCNAAYYTNGTNAGYACNYTN AARACNGCNATGAARAARATHGARGAYGARACNAGYACNGARCCNAGYAGYAARGARGGN AGYCCNGAYAARGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARTGYGCNATHGAYYTNCARCCNNNNCARTGGGAYTCNATHGGNGGNYTN GARGARGTNAARGCNGARATHMGNCARTCNGTNGARTGGCCNYTNYTNTAYCCNGARATH YTNAGYMGNATGGAYATHTCNCCNGCNAARGGNYTNYTNYTNTAYGGNCCNCCNGGNTGY TGYAARACNACNYTNGTNMGNGCNGCNGCNACNGCNAGYCAYGTNACNTTYYTNTCNYTN AAYGGNGCNCARGTNTAYTCNCCNTAYGTNGGNGARTCNGARMGNATHGTNGCNGARGCN TTYCARAARGCNMGNGCNYTNGCNCCNACNATHYTNTTYTTYGAYGARATHGARTCNYTN GTNGGNAARMGNAGYATHGGNAGYGGNCARTCNMGNGTNCARGARMGNATH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------MGNGTNTGYCARGARAAYAGYYTNYTNATGGCNAARYTNGAR GCNMGNTCNGARGARYTNAARMGNATGACNGCNCAYAARTCNGCNATHGCNMGNGARAAR GAYGARYTNYTNGCNYTNYTNGAYGTNACNGARMGNYTNAARTAYGARCARGGNAARAGY YTNATHGCNGARGAYGARTAYGGNTCNTTYTCNTCNTCNGARYTNGCNGTNYTNGGNGCN TGYAARTGYMGNGGNGCNGAYCCNGARCCNTGYGGNTGYGCNCAYGCNGCNGCNAAYYTN CAYAARGARGTNGCNAARYTNMGNGARGARATHAARCAYYTNCARCARMGNMGNCARGAR GCNGARGARCARYTNTCNAARTCNMGNTCNATHAGYCARCARYTNGCNGAYATHTCNTCN YTNACNCCNMGNTCNGTNAARGCNAARGCNGCNATGAARTAYYTNYTNCARGTNYTNAGY GAYGAYGAYTTYGAYGAYCARYTNAAYAARAARAARGARAARGARGARAAYYTNAAYATG TCNCARGAYTCNCCNYTNAAYYTNCAYGARYTNGTNCARGTNYTNACNGAYATGGTNTAY GARAARAARGARATHYTNGCNCAYCARAARYTNGCNTCNCARGTNYTNGCNAAYAARYTN AARYTNTTYGARAAYATGACNYTNTTYTTYMGNYTNAARGGNACNGTNAAYACNYTNTTY ACNAARCAYYTNTTYGTNACNAAYGTNGCNGTNAGYGGNACNYTNYTNGGNGTNAGYGAY TGGATHGTNCARAGYATHAARMGNMGNGTNGARAARGARGARTAYAARTAYGAYTAYGCN MGNACNGGNMGNATGGTNGCNATHGGNTGYTGYYTNGGNCCNTTYAAYCAYTAYTGGTAY CAYTAYYTNGAYAARTTYGTNACNMGNCARGGNYTNCCNGGNGTNTTYCARAARATHYTN TGYGAYCARYTNGTNGCNGGNCCNATHTTYTGYTCNTCNTTYYTNATHGGNYTNTCNYTN YTNGARGGNCARGGNYTNAARGGNGGNATHAARGARTGGAARAAYAARTTYYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGYTNMGNAAYYTNTCNGARGARATGTTYCCNTGGYTNTAY AGYTCNGARYTNYTNAARAAYAGYATHCAYMGNYTNTGYACNAGYYTNAARACNGARCCN TGYACNACNYTNTTYTAYYTNYTNYTNGTNATHTTYGGNTTYGTNCCNTTYYTNTGYTTY TTYYTNTTYATHGGNGCNGCNTTYATHTTYTCNGTNGTNTGGTTYGCNGTNTGYCARGCN GTNACNATHACNGTNGCNGCNYTNYTNTTYGGNGGNTTYATGATHTTYYTNATHGCNATG TGYTGYTCNATHGCNAGYACNTTYAGYYTNATHATHCAYATHYTNTAYGGNTGGYTNGCN ACNATHCAYGTNGAYACNGAYYTNGARAGYGARCARAAYAAYGAYTCNATHCARGCNAGY YTNYTNYTNGCNGARGGNYTNTGYYTNAAYGGNGAYATHACNAARGGNACNGARGAYAAR GCNAAYGCNGARAARGTNCARATHYTNGAYYTNATHGAYAARCARCARGARACNGARGAR AAYGARYTNACNTAYAARYTNGCNYTNGARCARAAYGARGARGCNGARAARYTNMGNAAR GARTAYGCNATHMGNAARMGNATGGGNATHAARGARATHCARCARYTNTAYATHGGNGAY GTNGTNACNCAYMGNAARGCNYTNGCNAAYGCNAGYGARACNCARGARGAYGAYCARACN GARATGYTNAAYYTNATHGCNTCNYTNCAYATHAAYYTNGTNCARMGNATGAARAARAGY AAYCAYYTNACNCCNGGNCARATHGAYAARTAYATGTCNCARGCNAARGCNGAYYTNCAR AAYGTNAARGGNAARATGGAYAGYGARAARGAYYTNCARGARGAYGCNATGTTYAARAAR YTNAGYACNYTNAARMGNAARAGYATHGCNGARAARATHAGYGARCAYGARGCNGARYTN CARGARTAYATHAAYMGNAAYAARGCNCARCARACNGARGGNCCNGTNGAYCCNGTNTCN TAYGTNGARGGNTTYGTNGAYACNAARTCNMGNCARMGNAARGGNYTNAGYACNYTNGAR AAYCARATHGAYYTNGAYCAYGCNAARCARYTNGARCARATGMGNGAYCARGTNTCNAAR AAYGCNAARAARGARYTNGAYGAYATHCARAAYAAYYTNGTNGGNAGYYTNAARGARGAY GGNGTNAARGAYGAYATHATHATGAARATGYTNAARACNCAYGARCARAAYGTNAGYGAY YTNAARTCNAARCARYTNATGAAYMGNAARGARCARGARGTNMGNYTNAARAAYGARYTN TCNCAYMGNAARMGNGARTGGGARGARAARAARGARCARGARAARATGGARCARCARGAR YTNMGNGAYCAYGARGCNGARATHGTNAAYAARYTNYTNAGYAGYCARGTNTCNATHTCN GARCARGAYMGNGAYMGNATHYTNAARGARCAYGARAARCARATGGTNAARYTNGARAAY AGYYTNACNYTNAAYAARYTNAARCARCARMGNATGYTNGARGARAARYTNGCNCARAAR MGNGCNMGNAARATGGARGARYTNCARCARAARCARAARGARGARYTNGTNAARCARMGN AARATHGCNGARAAYAAYGGNGARGAYGAYGAYGARGTNGTNCARMGNCARGARYTNGAR ATGATGAARAARCAYGCNCARCARAARYTNGCNYTNATHCARGGNCARCARYTNAAYTTY GAYGCNGARYTNGARGARATHMGNTTYGARATGACNAARGARMGNGCNYTNGCNYTNAAR GAYCARGARGARMGNYTNAGYGCNYTNATHACNTCNYTNCARATGGAYAARGCNMGNGAR ATGGCNMGNATHGARGARCARCARAARGCNATHAAYAAYYTNAARGCNAAYYTNATGGAY GAYYTNAAYGCNMGNGGNATHATHTCNACNCCNGARTGYGARCARATHYTNAAYATHCAY AARGARGAYCARGAYAARATHAAYAARAARYTNGAYAAYCARMGNGCNAARCARGARAAR GCNYTNAARATGAARYTNCARGARMGNATHCARCARMGNGARAGYTCNATGGTNCARAAR CARGAYGARGARATGAARAAYYTNYTNGAYAARGCNACNAAYAARAARCARAARATHGTN CARGARCARGARYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GCNMGNGARGARMGNTGYGAYATHAARCCNYTNGARGTNGARGAYGTN ATH---AAR---CCNAAYGCNAGYGGNATHATHCCNGGNMGNGTNGTNMGNMGNGCNAAR MGNCARGTNAGYGCNACNAGYAAYAGYTCNGCN------------------AGYGARGGN GGNACNGTNYTNAAYTGYCARYTNGARAARYTNTCNMGNYTNATHGARCARYTNGARACN AARATHAAYTTYGAYTGYTTYMGNGAYGARGARGTNGTNACNGGNGCNGAYGAYACNYTN YTNYTNGTNMGNMGNGARTTY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGNAGYAARYTNGARGARMGNATHCARGCNYTNGARGCN ---GARYTNACNAGYMGNATHGAYGGNGCNCCNGGNCAYYTNCCNGCNGCNTTYATHGAR TCNGAYTTYMGNGTNAARYTNGCNGARAARGAYTCNATGATHGCNMGNATGYTNTCNMGN AAYCARGARYTNYTNGCNAGYMGNAARCARATGGARYTNGARAAYACNCARYTNACNATG MGNGTNACNGARMGNAARGGNCAYGTNGARATHYTNGARGAYGCNYTNYTNAAYGCNCAR GCNAARGTNYTNGCNYTNGAYGARGARAAYCAYAARAARCARGCNTGYGCNGARACNGTN GARCAYYTNAARACNGCNYTNTCNTCNYTNCARYTNGTNAGYAARCARGARAARAARGAR AARGARATGMGNGTNAGYYTNGARAARGARYTNGAYAGYTAY---------AARACNGGN GTNAARATGGARTCNAARGAYGAYGAYAARAGYGTNAGYATGYTNMGNAARATGYTNAAY AARGAYGGNMGNATGCAYYTNGARAARGAYATGGCNGGNYTNGARCARAARTAYGTNAAR GARGTNCCNYTNMGNCARYTNGGNATGGCNAGYAGYCCNAARCCNTGYAARGARGTNMGN CARGCNGCNYTNGARAARACNTCNTCNGAYATGGARAARYTNATHGAYGARGCNAARATG GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MGNCCNTCNMGNGAYGAYAARMGNGCNGTNCARGARMGNATHAARGARYTNCAR GARYTNATHCAYCARGARCARAAYGTNATHATGCARACNAGYAAYGCNYTNAAYAARTGY TGYYTNGGNAAYGCNTAYTTYGCNGGNTCNCCNGARCARGTNGARTGYAAYMGNATHYTN YTNYTNGCNTGYAARAARMGNGARGTNTAYATGACNGARATHCARATGYTNAARAARACN GGNATHYTNTCNCCNGTNAGYGCNGGNCCNCARGGNTCNYTNACNATHAGYGAYATHMGN YTNCCNYTNAARAARGARTTYGTNACNAARATHGGNACNTCNCARGAYAGYACNACNCAY TTYTTYATHATHYTNATHMGNAAYGGNTGYCARGTNATHTGYACNCARATGYTNTCNACN CAYGAYCCNACNATHMGNGGNAGYYTNGAYTTYCCNAAYYTNATHAARATHAAYGGNATH ACNGGNAAYTTYAARYTNACNYTNGAYATHTAYAAYATG--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GCNGAYATHATHGTNTTYCCNGARGAY GGNGTNTAYGGNTAYATHTTY---AAYMGNACNTCNGTNTAYCCNTTYYTNGARACNATH CCNGAYCCNGCNATHATHACNTGGTCNCCNTGYTCNAAYCCNAAYCAYTTYAARGAYACN GARGTNCARCAYAGYYTNAGYTGYATGGCNAARAAYAAYACNATHTAYGTNGTNGCNGAY ATHGGNGAYAARGTNCCNTGYGAYAARMGNAGYGAYCCNAARTGYCCNGAYGAYGGNMGN TAYCARTAYAAYACNGTNGTNGTNTAYGAYCCNCARGGNACNYTNGTNGCNMGNTAYCAY AARMGNCAYYTNTTYTAYGARTTYCARTTYGAYACNCCNGAYGCNAARGCNGARTTYTTY GAYACNCCNTTYGGNMGNTTYGGNATGGCNGTNTGYTTYGAYYTNYTNTTYCCNGAYCCN GCNATHGAYYTNGTNACNGTNTTYAAYGTNACNAAYATHYTNTTYCCNACNGCNTGGATG GAY---------GTNYTNTCNGCNATHGGNTAYCAYTCNTCNTTYGCNMGNGGNYTNGGN GTNAAYYTNYTNGGNGCNAAYYTNCAYMGNCCNAARTTYMGNTTYCAYGGNAGYGGNATH TAYACNCCNAAYGGNACNGCNAGYTTYTAYTAYAAYAAYGAYGTNAGYTCNCCNGGNAAR YTNYTNGTNTCNAARATHGAYGTNYTNCCNGAR--------------------------- ------------------------------------------------------------ ------------------CCNMGNMGNCCNAAYGTNCARCCNAAYAGYAARTCNGGNACN CCNAAYCCNTTYCCNGTNGAYAARGARCARGARTTYCAYTCNGAYGTNTTYTAYGAYMGN TTY---------------ACNTTYMGNATHYTNGAYAARCCNMGNTCNAARTTYMGNGTN TGYGAYAARAAYGTNTGYTGYCAYATHAARTAYGAR------AARGARACNAGY---AGY GAYACNTTYGCNTTYGGNGCNTTYGAYGGNGTN------CAYGARGGNCARTAYTAYATG CARATHTGYACNYTNYTNMGNTGYGCNGAYAGYACN---AAYMGNTCNACNTGYGGNGCN TCNACNTAYGARTCNTCNACNAARTTYAARTAYYTNYTNGTNGGNGGNGARTTYCARACN AARTAYGTNTAYCCNCARATGGTNYTNTCNGARMGNGGNCARYTNGARYTNGTNGAYCAR GAYCARTGGGARTTYACNGGNAGY---GARATHAARTCNCCNTTYGGNGTNACNAARCCN ATHYTNTCNGTNACNYTNYTNGGNMGNGAYTAYAGYMGNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TAYMGNCAYYTNACNGGNYTNYTNCCNTCNMGNYTNAAY------CARTCN TAYCCNACNTCNAGYCCNACNMGNGCNGARATGCCNATGTGYAARGAYTAYYTNAAYGGN GAYTGYAARMGNGGNTCNAARTGYAARTAYMGNCAYYTNACNAARGAYCCNGAYGCNTCN GAYMGNAARTCNAGYMGNGAYTAYGAYMGNMGNGAYGARMGNAGYTCNTTYGAYCAYGGN TCNGAYGCNAARMGNMGNMGNYTNGAYGARGAYTAYGAYMGNATHGAYMGNGGNYTNAGY TAYAGYTAYYTNGARGAYGARAAYACNATGYTNMGNMGNAARGTNGARGARTTYAARAAR CARGTNTCNGAYYTNACNGCNATHYTNAAYMGNTTYMGNCCNYTN------CCNCCNGCN CCNGCNCCNMGNCCNGTNAGYCARCAYATHGGNYTNACNGAYCCNTAYAAYTCNYTNTCN AARGARGCNCARACNTTYACNGAYMGNGTNACNTCNATGGGNTTYYTNMGNGCNAARGTN GCNMGNGCNGTNGARAARTTYGGNCARGAYGARAARGARGTNYTNGAYCAYYTNTTYGCN GTNGAYCARYTNGTNGARAARAARTAYGCNCCNYTNCAYGTNGARACNGCNYTNCAYAAY TGYCARAAYGAYATHGARAARGCNGARCARTTYYTNAARATGCARACNCARTTYGARGAR YTNGGNTTYMGNAAYGARAARATHCARGAYGCNYTNGTNAARTCNGARATGGAYCAYGAY AARGCNYTNGAYYTNYTNACN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GGNCARACNGCN GARGTNGTNGCNACNCCNTTYGCNGCNYTNAGYCCNTCNGTNTTYTTYAAYTCNTAYAGY MGNGGNGTNATHTGYAAYGTNAGYGGNMGNAARAAYTGYTGGATHGTNACNGAYGCNMGN TGYATHCCNGGNTCNGARGGNGGNCCNYTNTTYGTNTCNAAYGAY---ACNGARAGYMGN MGNTAYYTNTCNGGNATHGTNGTNTCNTCNYTNTGYTGGAARAAYAAYGARTGYATHGGN TTYTCNYTNGCNTGYAGYATHAGYAGYATH------------TGYCARGCNATGGCNGAR TCNAAYAGYACNAARATHATGCCNGCNYTN---------TAYAAYGCNACNYTNCARACN CARCARAAYYTNAAYATHTGYCCNAARGARACNGCN------------TTYCARTTYGCN ACNGTNYTNGTNCARGTNGGNAAYACNTGGGGNTCNGGNATHATHGTNGAYMGNCARAAR GGNYTNATHYTNACNTGYAGYCAYGTNYTNMGNAAYGCNGAYCAYYTNGCNGTNACNATH ACNGCNTTYAARAAYTCNGARTCNTAYCCNGCNAGYGTNATHTAYMGNMGNAARTCNYTN GARMGNCCNTAYGAYATHGCNGTNYTNAARTGYCCNAARGCNACNAGYCAYYTNCCNTGG GAYTGGTCNATHGAYGTNTGYTTYCCNGTNGTNGGNCARGARGTNAGYGTNATHGGNCAY GGNYTNTTYAGYACNCAYYTNGGNYTNGARCCNTCNATHTCNACNGGNGTNGTNTCNAAR GTNAAYACNCAYCARTCNAARCCNGTNATGGTNCARACNACNTGYGCNGTNCAYCCNGGN ACNAGYGGNGGNCCNYTNYTNTCNTCNGAYGGNAARYTNGTNGGNATHGTNGTNTGYAAY ACNAARGAYAAYAAYAGYAAYACNAGYTTYCCNCAYGTNAAYATGAGYATHCCNGCNGTN TCNGTNTGGTCNAAYYTNCARYTNTAYYTNCARACNGGNGCNTCNAARTCNTTYTCNGAR TGGGAYATHAARGAYCCNGTNATHGCNYTNYTNTGGGCNGTNGGNGTNTCNACN------ ------------------TTYATHMGNCARAARAAYGTNAARGTNCARATHAGYAAYAAY CARCCNGGNMGNAAYGTNMGNCCNAAYCARACNTCNAAYTTYTCNCCNMGNCAYAAYTTY ---------AARAARCARTCNMGNGGNGGNTTYGAYGCNMGNTCNAARYTNGGNCCNMGN GCNGTNGTNGAYGCNMGNGAYAARATHATHATHAAYAARAARAGYGGNAARGGNGAYGCN MGNAAYAARATHGTNCARAARCARGTNCARAARGGNACNTTYGAYGCNMGNTCNYTNYTN CARMGNCARTCNAGYAARGGNAAYGGNAAR------------------------------ ------------GTNAARAAYCCNCCNAAYYTNCARCARGTNACNMGNACNYTNTCNAAY CCN---CCNAARGGNAAYATHAAYGGNYTNCARGTNACNMGNCARGTNCCNAGYACNGAY GTNTCNATGTCNGGNAAYAGYYTNCARGTNACNAARMGNATHAAR---------GGNGGN ACNCCN---YTNGAYGAYGGNGTNCCNATHATHCARATHMGNAAYGAYMGNTAYCARCAR ------------------------------------AARCCNCCNAAYCCNCCNGCNCCN AAYTAYCCNGGNCARACNGCNTCNCARCARGGNGGNTAYGGNCARGCNTAYGTNGAYGAY TAYCCNTAYGAYMGNCCNGCNTAYCCNGCNCAYMGNCCNTAYATHGAYYTNGAYAAYCCN GAYTAYAAY---GCNGCNTCNGTNGCNYTNCCNGCNATHCCNAARATHCAYATHGCNAAY ATHAARGCNGTNGARGCNGCNGGNATGMGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GCNAARYTNGCNATHAARAAYYTNTCNGCNGTNAARAAYYTNCCN GGNGTNTGGGAYATHTTYATHTGYAARATHATHGARATHTAYGARCAYTAYMGN------ AAYGARGCNAARTCNATGYTNATHGCNTAYMGNAAYAAYAAYCCNAAYAAYCCNAAYGCN CAYMGNTTYYTNTAYGARTTYGARATHCARCAYGAYGGNGAYCARAAYYTNATHYTNGAR TGYYTNCARAARYTNTCNMGNYTNGAYCCNTGYAAYCCNYTNATHATHACNYTNTAYAAR AAYTCNTCNAARCCNACNCCNGARTCNATHTCNYTNYTNTTYAGYTAYYTNGAYTTYGAY CAYTGYAARAAYGAYGTNCAYGTNTGGMGNYTNYTNGCNGARTGYYTNACNAARGTNGAR AARTCNAAYCARTAYGAYACNGCNGTNCARCARTGYTGGGAYGTNMGNAARGAYTGGTGG CCN--------------------------------------------------------- ---AARAARCCNCCNAARTGYTCNACNTGYAARGARATHGTNGAYAAYTTYCAYGCNGGN YTNGTNGCNACNGCNAARTCNAAYTAYGGNGGNGGNAAYACNAARTGGGARGARAARTCN YTNGGNTCNTAYGCNTTYAGYGARGTNMGNYTNGTNGARATHYTNGARAAYYTNTGYGAR GGNAARTCNAARGARTGYCAYACNYTNYTNGARGARCAYGARGAYYTNYTNGARCAYTTY TGGTTYAARGARTTYAGYCARAARAARGGNACNGAYTTYCAYCARTTYTTYTGYATHGAY AAYATGAARGTNTGYTGYCCNAAYAAYACNTTYGGNAARGAYTGYTCNCCNTGYCCNGGN GGNGTNAARMGNCCNTGYGGNGGNAAYGGNMGNTGYGAYGGNGARGGNACNMGNGAYGGN AGYGGNACNTGYAARTGYTCNTCNGGNTAYAARGGNGAYATGTGYGAYGARTGYAARAAY GGNTTYTTYGARGARAGYAAYGAYGGNTCNGAYGTNGTNTGYYTNTCNTGYCAYATHTCN TGYAARGGNGARTGYTCNGARGGNGGNCCNAARGGNTGYGARGARTGYAARGAYGGNTGG YTNGCNAAYGARGARGARGGNTGYCARGAYATHAAYGARTGYYTNGARGAYCCNTGYGAY GAYAGYCAYTAYTGYACNAAYACNCARGGNTCNTAYTCNTGYTTYTCNTGYCAYGTNGCN TGYATHTCNTGYACNGGNTCNGGNCCNGARAARTGYAAYGAYTGYAAYGARGGNTTYAAR AARCAYGAYAAY---GGNACNTGYGARGAYATHAAYGARTGYGCNATHAAYTCNGARYTN TGYACNAARGARAAYGARGARTGYATGAAYACNGAYGGNAGYTAYGARTGYACNTGYAAR TTYGGNTTY---GARTAYAARGAYGARCARTGYGTNGARATHCCNACNGAYAAR---GAR GGNAGYGARAGYYTNGARGARGAYGCNGARAARGGNGARACNAARAARATGGGNGGNACN GARAGYTCNMGNMGN--------------------------------------------- ------GTNATHGTNGARGAYACNAAYGGNGARGGNGTNTCNCCNCCNAGYTCNAGYTCN TTYTGYMGN---GAYGARGARATHTAY--------------------------------- ---------MGNTCNATGAGYAARGAYATHGARGAYTTYTAYATGGARAARYTNAAYGAY YTNCARCARMGNAAYGCNGCNYTNCARCAYAARACNAAYGARCARTTYGTNGARGCNGTN AARGARGTNGARCARAARTTYYTNAAYTAYACNTCNTCNCCNGTNTGYCARGAYYTNCAR AGYAARYTNYTNCARTGYTAYCARGCNAAYCCNTCNGARTCNYTNAAYTGYTCNTCNATH GTNAAYGCNTTYGCNATGTGYGTNGAYMGNGCNMGNATGTGYGCNACNATGACNATGGAY AGYCCNGARGGNYTNGTNGCNATGGARGTNGARMGNTTYTCNAARYTNGGNACNYTNAAR YTNCARCARGGNCARYTNGAYAARGCNYTNGAYGCNTAYAARAGYGCNTTYAARTGYTCN CARGGNYTNAARCAYAAYGGNTAYATGCARMGNGCNTGYACNTTYAAYATHGGNGCNATG YTNATHTCNATGAARAGYTAYCARGARGGNYTNATHTAYYTNAAYATGGCNYTNCCNCCN GARGCNAARMGNGAYGGNMGNTCNAAYGGNGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TCNAARTCNGAYTGGCCNAARGTNGAYMGNGTNATGATHTGG AAYGARTAYGARGCNTAYGTNGTNCARTTYAARCARATHGCNGTNTCNGCNTGYGGNCAR ACNGCNGTNYTNAAYGTNATGAARGCNYTNAARTTYAAYTGYGAYAARGCNGCNGTNTGY AARGTNATHAARACNAGYYTNMGNAARGARGAYAARGAYATHCCNGARTAYYTNTTYTCN MGNGCNTGYGCNGGNACNACNGCNACNGARYTNAARGARGGNGTNGARAARYTNAGYGGN GGNGCNATHGGNGGNMGNTTYTTYCAYTTYTGGCCNCCNMGNAARGTNAARYTNYTNCAY TGGYTNGCNCAYTGGATGAARMGNGGNGTNATHCCNATGGCNACNATGAAYYTNCARCAR GGNCCNCAYTCNATHTGGGARGTNCCNGAYTCNTGGCAYCAYCARATGGTNTAYGGNGTN AGY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AARAGYCAYAAR GARGAYYTNGARCARAGYCARAARGARACNAAYAARGARAARAGYGTNCCNGAYGCNTCN AGYTCNAARGAYYTNGCNACNTCNGGNGAY------MGNGARGARAAYGARGARCAYGAY GAYGCNATHTCNAAYATGACNMGNGAYGTNTGYGCNGAYATGYTNGARTCNYTNATHAAR YTNAARCARYTNGAYGTNGAYAAYCCNAAYATGGARCAYATHYTNAARATGCARGARCAR YTNGAYAARYTNCARAARTCNYTNGGNATHCCNMGNGARAARAGYAARAGYAGYMGNGTN TCNCAYGARAARGARGGNAAYCCNTGGACNGTNGARGAYCAYGAYAGYAGYAARGGNTCN ATHAARAARCARGAYAARCCNGCNGGNAARAARAARMGNGAYGAYGARCAYTGGGARGAR ATHTTYGARGARACNATHAARGCNGARMGNCARAARGARGARMGNYTNAAYCARCARMGN GARTTYGARATGMGNMGNGARMGNGARATGGARGARAARMGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNCARACNCARYTNGGNATHTCNTCNGGNGARGARYTN CCNGTNGGNGCNAARCCNGCNTCNAGYMGNGAYAARATHGTNMGNCARTCNYTNAGYGAR MGNGARGAYGARTTYACNGAYYTNAARATGYTNAAYGTNTTYTGYGGNACNTGGAAYGTN AAYGGNCARTCNCCNTCNGARTCNYTNCARAARTGGATGGARGTNGAYAAYGAYCCNCCN GAYATHTAYGCNATHGGNTTYCARGARYTNGAYYTNAGYAARGARGCNTTYATHTTYAGY GAYTCNCCNAARGARGARTGGCARGAYGCNGTNAARAGYTGYYTNCAYCCNAARGCNMGN AARGTNAARTCNGTNMGNYTNGTNGGNGTNATGYTNATHGTNTAYATHCARGARAARCAY TTYCCNTCNGTNACNTTYATHGAYGTNGAYTCNGTNGCNACNGGNATHATGGGN------ ---------ATGTGGCAYGARGCNMGNMGNCARGARAARAARATHMGNGGNYTNATGGTN GAYTTYAARMGNMGNGCNGAYMGNMGNMGNGARTTYTAYGARAARATHAARCARGAYCCN ACNCARTTYYTNMGNATGTAYGGNMGNCCNGTNAARATHCAYYTNGAYCCNGCNGTNGCN ATGGCNGCNGARGGNCCNCARAGYATGATGCCNTGGCARGGNGAYAAYTCNAAYATGATH GAYMGNTTYGAYGTNMGNGCNAAYYTNGAYYTNATHCCNGARTAYGTNCCNAAYTCNTCN AGY---------TCNATHGCNGAYGAYGAYGARGARMGNYTNGCNAAYTAYGARMGNTAY MGNACNYTNGTNGARAGYGARGCNAGYGGNYTNTCNGARGARCARTGYYTNCAYCARATH TAYYTNGAYGARCAYTTYGGNACNATHAAYAARACNAAYGARGARGARAARAARAARAAY GCNGAYAARAARGCNGCNATHGGNTTYATHTAYGARGAYAGYACNCCNATGGARAARAAR GARACNGARGAYGGNGARGAYGARGARAGYGARGAYGAYYTNGARACNGCNGAYYTNGAY GTNACNATHGAYGTNGAYACNYTNACNTCNGARCARGCNAARGARGTNAAYYTNTGYGCN ACNCARTAYGGNATGAARGAYGAYGAYTTYGTNMGNYTNYTNMGNCARGAYAARGARGAR YTNGAYGCNYTNAARGARGCNMGNCARYTNGARGARGCNAARGCNCARTTYTCNGGNMGN AARTCNMGNMGNGARMGNMGNGCNATHAAYGARAARAARCAYAAYCCNYTNMGNTTYAAY MGNCCNAGYTAYGCNGCNMGNGARAGYCCNAARTAYGARCCNTAYAARMGNCCNGGNTCN TCNTCNMGNTCNMGNTCNCARTCNGGNTCNCARTCNTCNGARGAYGCNAARGTNAARTTY ATHACNAGYTTYGGNAAY---GAYAGYGAYGARGAR------GGNGTNATHCARGGNCCN YTNYTNCCNTTYGCNGCNCARCARACNTCNGCNAARCCNAARAAYTCNGARCCN------ TCNAARTGYGARACNCCNTGGGGNTCNAAYAAYTCNMGNAARAAYMGNAARTCNGAYMGN TCNTAYTCNCAYTCNMGNTCNMGNTCNMGNTCNMGNMGNMGNGGNAGYMGNTCNTCNTCN AGYMGNTCNMGNTCNMGNTCNMGNTCNCAR---MGNTCNMGNTCNGGNTCNMGNAAY--- GAYAGYMGNTCNMGNMGNAAYMGNMGNTCNGGNAGYTCNAGYTCNTCNMGNTCNMGNAGY MGNTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARMGNTCNATGAGYTGGTCNGARTCNGGNGAYGAYTAYATG TCNAARATHGGNGTN---------------TAYTCNMGN------------ACN------ ------GCNGARATGGARGARGARAARATHCARCAYTAYAAYAAYTGYATGATGYTNAAY CCNGARATGAAYGTNCARTAYGARCARATHAARMGNTCNTAYGCNAAYYTNYTNTAYAAY TGGMGNYTNYTNAAYCARMGNACNCARATHYTNAARCAYACNTGYAGYCCNCARACNGGN TCNCAR---ATHGCNTTYCCNGTNACNTGYTTYAARTGYTCNGARAGYGTNYTNGGNGTN CARTGYGGNMGNTGYTAYTAYGCNGCNYTNMGNTGYTCNATH------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNYTN GARATGCARGARTCNYTNGARGARTAYCARAARMGNACNAARGARMGNACNACNAARATG CARACNAARGARGAYGARYTNGGNGAYCAYYTNTCNTCNGTNACNCARGARMGNGAYGAY YTNATGGARCARYTNTCNGAYATGGARYTNTCNGCNGCNTCNCAYGARGCNCARATHAAY MGNYTNYTNAAYGAYGTNACNTCNGARGAYGCNAARTCNCARGARGTNGARCARAARAAY TCNMGNYTNCARCAYCARYTNGAYYTNYTNATGGCNCARATHAGYGAYTTYGARAARGGN ATGCAYGARGCNAARGTNATHAARAARGARAARATGTTYYTNGCNTCNGARYTNTCNGAR CAYMGNGTNATGGCNCARGAYYTNMGNGCNYTNYTNGARATGYTNCARYTNAGYTAYACN GCNGAYGTNCARGAYGAYAGYGGNCAYTTYAGYATHCAYACNATHCCNGGNAGYGGNAAR TCNGTNMGNATHACNGARAGYAGYGARGGNGCNYTNYTNGCNGCNGARYTNAAYTGYAAY AAYAAYGGNYTN---------------GGNTGYGARGGNGCNAAYATGATGTGYGARATG MGNAAYYTNGTNACNAAYATGGAYTGYGARATHCARMGNYTNMGNGCNGAYYTNAARCAR MGNGAYGCNGAYGAYAARACNTAYTCNAAYYTNMGNGAYGARYTNAARGTNYTNATGGAY MGNGTNGARTGYGGNATGTGYMGNAAYCARGARYTNGARTGYTGYGTNGCNTCNYTNCAR GARGAYAARAAYAAYTCNYTNAARAARYTNGARGARGCNYTNAAYTGYYTNGARGARMGN GARMGNACNATHCARTGYYTNGARACNMGNYTNAAYGARMGNAAYAGYCARGTNGTNTGY YTNCARGARGAYATHGAYGAYAARATGCAYMGNATHGGNTGYYTNGAYCARGARYTNMGN GAYATHCAYAARMGNYTNAGYGARGGNCAYAGYGGNYTNGAYACNGTNGCNYTNGCNGAR GCNYTNTGYMGNGTNAARGAYYTNGARGCNYTNYTNGTNTGYAARACNAARTCNYTNGAR GAYYTNCARTGYAARYTNGCNAARAGYYTNAARGARAAYMGNYTNYTNAARACNGARACN GAYAARCARGTNGARTGYYTNAGYTCNGGNYTNATGGARACNCARAAYCARYTNGARGCN YTNACNATGGARAAYGARGCNATGMGNCARAARYTNATGACNATGAAYAARYTNATGGAR GAYYTNMGNAARACNTGYMGNGCNAARGAYGAYAARATHGCNTGYTTYTGYGCNGAYYTN GAYGARGCNAARTTYGCNAARCARGARATGCARGAYAARYTNACNYTNCARATHGARAAR ATGCARGARTGYYTNMGNATGTCNCARGAYCARGTNAARGARYTNGARTCNGCNYTNYTN ATGTGYMGNAAYGARGTNGCNAAYCAYYTNAARACNATGGARGARATHMGNYTNCAYTTY CARTGYGARYTNGAYCARMGNGAYACNTGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CAYAAYGGNAARAGYMGN AGYTTYCAYATHGCNGGNACNGARTTYCAYATHCCNCARGAYTGGCAYAGYGGNGGNGTN GCNGCNGTNGTNTGGGAYGCNGCNGTNGTNYTNGGNGARTAYYTNGCNGTNCAYACNGAY ATHGTNAARTCNAARACNGTNYTNGARYTNGGNGCNGGNACNGGNYTNGTNGGNATGGTN GCNGCNTCNYTNGGNGCNAAYGTNACNGTNACNGARMGNGCNGTNGCNATHCCNTAYYTN GARTCNTCNYTNTCNTCNAAYGAYGCNACNGCNMGNTGGTGYATHCARGCNCARACNYTN GAYTGGACN------------GAYACNACNACNGTNAAYACNMGNTTYGAYGTNGTNYTN GGNGCNGAYATHATHTAYATHGARGARACNTTYCCNAAYYTNYTNAARACNYTNAARGCN GTNGCNCCNGAYYTNAGYGTNACNATHYTNYTNTCNTGYMGNATHMGNTAYAARMGNGAY GTNMGNTTYYTNMGNATGYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------TGYAGYATHTGYACNCARAARCARAAYCAYCAYTTYATHGTNCCNAARTGYCAR TTYACNYTNYTNCARGGNGCNGAYTGYYTNACNACNTAYACNTTYAAYACNCAYAARGCN AARCAYACNTTYTGYAARATHTGYGGNGTNCARAGYTTYTAYACNCCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CAYYTNYTNTTYACNTAYGGNACNYTNAARMGNGGNCARCCNAAY AGYTGYGTNATGTCNGAYGTNAAYAAYGGNGARGCNAARYTNYTNGGNAGYGGNTGGACN GTNACNAARTAYCCNYTNGTNGTNGGNACNCAYTAYCAYGTNCCNTTYYTNYTNAARGTN CCNGGNATGGGNCAYGARGTNMGNGGNGARYTNTAYGARGTNGAYAGYGCNATGYTNGAR TTYGTNGAYGAYTTYGARGGNCAYCCNAAYYTNTAYMGNMGNGARYTNTTYCARATHAAR YTNACNGARGAYAARGAYGGNCARCCNATHAAYACNYTNCAY------GARTGYTGGGTN TAYTTYYTNTCNAARGTNAARGARGAYTTYYTNCARYTNGARATGYTNAARGAYTAYAAR TCNGTNTCNGARGAYCAYMGNCCNTAYGCNGARMGNMGNGAYMGN---GARGCNTCNAGY TTYGARGAYACNMGNTGYAARTGYGTNTGYGAYAARACNTGGGAYGCNTCNGGNAARGAR AGYMGNGTNGTNTTYATHAAYACNACNMGNAGYGARCARTGYGAYTGYGARCAYGTNGTN MGNCCNYTNTCNCCNYTNATGGCNTGYTCNMGNTGYYTNTGYMGNACNGARACNMGNAAY ACNACNACNATHAARGTNGTNGTNATHTTYATHATHTGYGTNGTNATGYTNYTNTTYGTN TAYATGYTNTTYYTNYTNTGYYTNGAYCCNYTNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AGYAAYGGNGGNACNTCN CCNAARCCNTCN------------------------------------------------ ------------GAYTAYGCNAARACNMGNGTNMGNTAYTAYMGNAGYTCNGTNAARYTN YTNAARAAYGCNGTNAAYCAYTGGAARAGYAAYAGYAAYCCNYTNTCNTTYGTNYTNCAR YTNGGNGAYYTNATHGAYGGNAARAAYAARMGNGGNGARGCNCAYAGYAARGARGCNYTN AAYACNGCNYTNCARCCNTTYAARTCNYTNAARGTNCCNGCNTAYCAYYTNATHGGNAAY CAYGARYTNTAYAAYTTYCCNMGNTCNTTYTAYYTNACNTCNCCNYTNAAYAGYGGNYTN YTNATHGAYTTY------------------CARTTYGGNGCNGARCAYYTNTAYTAYACN TTYCARCCNCAYCCNAARYTNMGNATHATHGCNYTNGAYGTNTAYGARATGAGYYTNATH GGNTAYCARGAYAAYGCNCARAAYGARAAYCAYYTNACNGCNAARGARTGG--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AAYYTNAGYGARAARTCNAGYTAYCCNGTNACNAAR AARAGYCCNTAYCAYMGNYTNGARAARCARGTNGCNGARYTNACNAARCARYTNAARGAY YTNAAYAARYTNCCNACNAAYGARCAYYTNATGGGNAARACNAAYGGNAARGAYACNGAY MGNCCNATHGCNGAYATGTGGCARTAYATGCARYTNAARAARMGNGTNGAYGCNAAYGAR GARGGNGTNGGNAARYTNATGTCNYTNGTNGARGAYYTNATGGGNGARATGMGNGAYATG AARAARGCNCAYGAYGARYTNATGAAYAARGTNAAYGGNATHAAYYTNGAYGAYATHCAY AARMGNYTNAAYGAYATGGAYGCNYTNTTYAARGAYATGGARAAYAARTAYAAYGAYATG AAYGGNMGNYTNGAYAAYGTNCCNTCNYTNGAYGAYATHGAYCARTAYYTNTCNCARTTY GTNACNTGGCCNGGNYTNGARGAYGCNYTNAARGGNATHAARATGGAYTTYGARAAYYTN CARCCNATHAARGARGARMGNGTNGTNATHGARYTNGGNACNCARACNGARACNCCNAGY MGNCCNACNTCNGCNMGNCCNGTNTCNMGNGCNTCNTCNGCNCAYACNTCNGGNCCNACN TCNGARYTNYTNGAYYTNYTNGARMGNYTNGGNAARYTNTCNGARGAYCAYGARYTNYTN GTNAARMGNGTNAAYGARYTNGARMGNYTNYTNGARYTNAARGCNAAYATGAGYGAYYTN GARGGNYTNGGNATHTCNGARGAYYTNYTNGCNTCNYTNMGNACNATHCARGAYGARYTN AARGAYATGCARGARGGNCARTCNMGNAGYGAYGCNTCNATHMGNMGNYTNCARGARGCN YTNCARAARYTNCARGARGAYATHGAYAARYTNMGNTAYACNGTNGARGCNGTNGTNGAR GARAAYGTNCARMGNGTNAARGARATHCARGAYYTNACNGGNCAYTGYGAYAAYYTNGAR AARAARAARGCNGAYAARGAYTAYGTNGAYATGGARGTNGAYGTNAARGCNGAYMGNMGN CARYTNGARGGNAARGTNAAYCAYGGNYTNTTYGAYAGYACNACNAAYGARYTNAAYMGN ATGATHAARGAYATHYTNGAYAARYTNAAYGGNCAYGARGARGGNTGGAARGCNGCNYTN GCNAARGCNATGGARGARYTNGAYAGYAARYTNGAYMGNYTNGARYTNAAYAAYYTNAAR GAYTGGYTNGARAARCARYTNAARGCNYTNAAYAAYAARATHAARTCNATGGGNTCNAGY TGGAAYGTNGAYGAYGARGCNGCNGGNATGAARMGNCARYTNATHCARMGNTTYCAYTGY YTNTCNTGYGAYAARCCNGTNGAYGTNATGCCNAAYCCNCCNATHCCNTCNATHCCNGGN AAYTAYAGYYTNCCNAARTCNAARTCNCCNMGNCCNTAYATGACNTAYGARYTNGAYCAR ATHMGNCARCAYGCNMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TAYYTNGGNACNGTNTCNGARATH AAYATGACNAAYTCNAARAARMGNGAYACNGARGCNCARYTNATHGAYYTNGTNGARGAR AGYCARATHGAYGGNAARYTNATGGTNACNGCNATGGAYGARCAYAARGTNATHATGAAY GTNTCNMGNCAYGGNATHAARATHYTNGAYGTNAAYGGNAARGARGTNYTNCARMGNCAY CCNYTNCAYACNATHGCNCARYTNACNGAYTAYAAYGAYGGNTTYGGNMGNCAYAAYATH GCNGTNAARATHGGNCARGTNGGNAARAAYGTNTGYCARTGYTGYGTNTTYCARTGYCAY TCNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------GGNYTNGGNTAYYTNMGNGARTGGATGTGGTGGGCN GGNATGATHYTNATGACNGTNGGNGARTTYGCNAAYTTYGCNGCNTAYGCNTTYGCNCCN GCNACNYTNGTNACNCCNYTNGGNGCNYTNAGYGTNATHATHAGYGCNGTNYTNTCNGCN MGNGTNYTNAARGARAARYTNAAYATHYTNGGNAARYTNGGNTGYGTNYTNTGYGTNYTN GGNTCNACNYTNATGGTNATHCAYTCNCCNAARGARCARGARGTNCAYGAYGTNGARGAY YTNYTNYTNAARATGAARGARCCNGGNTTYATHGTNTAYGCNYTNYTNYTNYTNATHGTN TGYYTNGTNATGATHTTYTAYTTYGTNCCNMGNCAYGGNCARAARAAYGTNYTNGTNTAY GTNACNATHTGYGCNTCNYTNGGNTCNTTYACNGTNATGGGNTGYAARGGNGTNGGNACN GCNATHACNGCNACNGCNMGNGGNCAYAAYGARTTYAARAAYTGGYTNACNTAYGCNYTN ATHGCNGTNGTNGTNATHTGYATHYTNYTNCAYYTNAAYTAYYTNAAYAARGCNYTNTAY ACNTTYAAYACNGCNGTNGTNACNCCNATHTAYTAYGTNTTYTTYACNTCNTGYGTNATH GTNGGNTCNGCNATHYTNTTYMGNGARTTYTTYAARATGACNCCNYTNGAYATHATHGGN GAYYTNTGYGGNTTYYTNGTNATHGTNGTNGGNATHTTYYTNYTNAAYGCNTTYAARGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYAARGAYMGNYTNGCNMGNMGNGARAARGAYATHATGTAYGGNAARAAYACN GGNTCNTAYMGNCARTAYATHCARAARATHCCNMGNGARTTYMGNAAYGARGAYMGNAGY GTNCAYCCNGARACNCCNCARAARTCNMGNAARTGYAGYMGNMGNTCNTGGGAYTCNCAR ATHMGNAARTGGAARATHAGYYTNCAYGAYTGGGCNTCNAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGNAGYCCN AARACNTCNGCNTCNGAYCCNCCNCARGARGAYACNAAYATHGTNGARGAYYTNACNGAY ATHYTNYTNCCNTCNAAYCARCCNACNACNTCNGARAARAGYAARGAR---AGYYTNGAR GTNGGNAARAGYAGYGTNTGYTTYTCNTTYAGYAARACNACNAGYAARATHGCNACNATG TCNGCNTTYAAYCARGARGARCCNGAYCCNATHGARYTNCCNCCNGCNMGNCCNYTNACN YTNGTNGAYAGYATHGARGARGARAARMGNAAYATGAAYYTNGGN------------TCN GGNAAYGCNGTNACNGAYGCNGGNATHAGYGGNGCNACNACNGCNTCNTCNACNGCNTCN CCNTCNGGNCCNMGNCCNTCNGCNGCNGCNAAYCCNCAYYTNYTNGARACNTTYGTNAAR GTNAARYTNATGAARGARCCNTGYGARGARATHGAYTGGCCNGTNGARACNGTNAARTAY ACNAAYACNYTNCCNTCNATHCAYTAYGGNTGYAAYYTNYTNCARTTYAAYTTYAARGAY ATHATGAARCCNGGNAGYGGNCARGAYTCNAARGARCCNAGYGCNGARGCN---GTNGTN CCNGGNYTNAARTCNAARGARAGYACNGTNTCNGGNGGNGGNGAYAARGAYGGNAARCAR MGNAARAARCAY---TCNCAYAARAARMGNAARMGNAARAARAGYACNAARGARCARAAR GAYGGNAAR---GGNGARAARGARGAYGGNGAYAARAAYCCNGGNGGNGARAARGARGGN CARGARGGNAARGTNGARGARAAR---------AARAARAARAARAARAARAARMGNAAR CAYMGNCAYAARACNAARAARGARAAYGGNGARGARGGNACNGCNGCNGCNAARGARGAR ATGGARGGNGGN---GARCARAARGARMGNAARMGNTCNMGNMGNAARMGNAGYCAYAAR GARAARGAY------GGNGGNGARGARAGYAARGCNGGNGARGARAARGARGGNGAYAAR GARGTNGTNGTNAAYGGNGAYAARAAR------------YTNTCNTCNCAYMGNCAYAGY AARAARCAYAARMGNAARCAYMGNMGNMGNGGNTCNGCNMGNTCNGARAARGCNAARGCN YTNAGYGCNTCNGARAARGCNAARACNGTNAARAAYTTYGAYACNGTNAAYGCNAARGAR CCNAARGTNAARATHGAYTAYGAYGARGARGARGARACNCAYATHCCNTCNGAYAAYGAR ---CARGCNACNGGNGARCCNAARATHAARMGNTTYMGNMGNTCNAARAARMGNCAYMGN MGNAGYTCNGGNCAYCARGAYGTNACNGARGAYYTNGTNACNAARACNGARGARYTNGGN AARGAYYTNATHGGNTTYACNTTYAARACNCAYAARAARATGAARGARGARGCNTCNYTN CARGCNGARACNYTNGGNGCNGGNGGNYTNGAYAARCCNCCNATGATHCAYGCNAARAAR GARGCNGARAAYCARCCNYTNAAYAARACNCCNAAYGGNGAYGTNGGNGGNAAYMGNAAR MGNGGNGCNAGYGTNTCNAGYTCNGARGCNATHACNCCNGCNAARGTNAGYAARGTNGAR AARGGNGAYYTNTCNCARGAYACNTGGAGYAARATGGARGGNYTNTAYGARAARAARGAR GCNGGNGGNTCNAARAGYAARTGGGAYACNAGYGAYAGYGAYGGNGARGAYGCNYTNCAR AARACNATHGAYGCNAAYYTNATGGARGARGARGGNAAYAARCCNAARCCNCARCARCAR ---ACNCCNAARYTNGTNAAYGGNAARATHCCNAAYTCNAARGCNATHYTNGCNCCNAAY GGNYTNYTNGGN------------AAYCAYATHAARCARGARAGYYTNCCNATHAARCAY GARTCNAGYACNGCNGTNGGNGGNGAYAARACNTCNCAYCAYCAYCAYCCNGARGGNGGN GAYGCNAARGARAGYAGYGGNGGNGGNTCNACNCARAAYAARYTNGARMGNGARTCNMGN AGYAARAARAARAGYAGYMGNMGNTCNTAYAGYTCNTCNGAYTGGTCNTCNMGNTCNMGN TCNMGNTCNMGNTCNTCNTCNGGNTCNTAYMGNAGYTAYTCNGAYGAYTCNMGNTAYAGY GAYTCNAGYMGNACNCAYAGYMGNTCNTCNMGNAGYTAYAGYMGNAGYMGNTCNMGNCAY MGNTAYCAYMGNMGNMGNTCNTCNTCNAGYMGNGGNMGNMGNAGYCAYAGYTAYAGYAGY MGNAGYAGYTCNAGYMGNTCNMGNACNMGNTCNTAYAGYMGNTCNMGNAGYTAYACNMGN TCNMGNTCNMGNACNMGNACNMGNMGN---AGYAARTCNMGNAGY---YTNTCNMGNMGN ACNGCNAARYTNMGN---YTNYTNAARTCNCCNGTNYTNCCNCCNTCNGTNACNACNATH ACNGTNGCNCCNGTNACNGGNTCNACN---GGN--------------------------- ------GGNGGNGGNAARGGNGGNGGNGGNGAYCARCCNGAYGAYATHCCNYTNCCNGGN AARGAYGCNGCNYTNCCNGTNCCNACNTCNCARGCNGARAARGARATHGAYGARAARCCN ATHYTNAAYGAYATHCCNYTNCCNACNACN---GAYGGNGGNAARGCNGARGGNAARGAY ---AARGARGCNGCNACNGCNTCNACNTCNGGNACNACNCCNGCNACNGTNGGNACNGCN CCNATHACNGCNACNCCNYTNACNGCNACNCCNYTNACNGCNACNCCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYGAYGTNAGYYTNGARACNATHAARGTNTAYACN TTYACNAGYGAYGAYMGNGGNAAYYTNTCNGTNAARGCNATHCCNTAYMGNGGNCCNAGY GCNGCNGAYCAYAARGARACNTTYTGGCARGARACNGGNGAYACNAARATHCAYATHGAR ACNACNCAYTTYTGYGGNTAYTAYTGYACNYTNTGYGARACN---GAYACNTTYCCNCAY GTNTAYGTNGCNGCNTGYGGNTCNTAYYTNCARCARGARGAYAAYTCNMGNGARGTNMGN ATGTTYYTNYTNATHTGGGAYAARMGNYTNGTNATHAARGAYTTYTAYGARAARTTYGTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNYTNTCNGTNYTNGGNTGYCCNGTNYTNAARAGYACNGGNGARGCNGARAAR YTNTGYGCNCARYTNAAYCARTCNAARATHGTNGAYGGNTGYYTNACNGARGAYGGNGAY GCNTTYGTNTAYGGNGCNYTNACNGTNTTYACNGGNTAYAGYGCNGAR---AARCARACN TGYTCNGCNAARAARTAYGARATGGCNGCNATHACNAARGARYTNGAYYTNCARCARGAR GAYYTNGTNGCNTTYGCNTTYYTNAGYGGNTCNGAYATGTGYAARGGNGTNGAYGGNGTN GGNAARTCNAARTTYATHGARYTNACNMGNGARYTNAARMGNAAYGGNGTNACNAAYTGY GTNGARMGNYTNMGNAGYTGGAGYACNAAYGARGAYYTNAGYMGNYTNGARGARAARTAY AAYGARYTNAARCCNACNMGNAARACNGTNCAYTGYAARGTNTGYTGYCAYTCNGGNAGY YTNAARAARCAYGARAARGAYGGNTGYGGNATGTGYTCNACNGARTCNGGNTGYACNCAR ------------AAYGTNAAYAGYGGNGAYGAYATHACNCCNTGYCARTGYCCNTTYCAY ACNYTNGARACNTCNGTNATGCCNTTYAARGTNGARYTNAAYGTNMGNCARAGYGCNATH AARTGYGGNCARTTYYTNTCNGAYGARGTNATHAARGARTAYYTNCARAARGAYCCNATH GAYATGAGYGCNTTYAARGTNAARATGGARYTNCCNGAYTTYGGNAARGTNTGYGAYAAR GCNAAYTAYAARTTY---------AAYAARACNYTNYTNCAYYTNATHCCNGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHGARCARMGNGGNAAYTTYTTYATHATGGAYTCNGARCARYTNGTN GCNAAYCCNTTYCARGAYATGCARCARGARGCNGCNAAYGARTCNCARAARMGNAGYACN ATGACNGARMGNATHACNAGYGTNAARAAYAAYGTNTGYGARAAYCAYTTYCARATGGCN AARGGNMGNYTNGARMGNCARAARACNCARMGNYTNAARCARYTNTAYGAYCAYTCNAAY AARYTNMGNCAYGARGCNAARYTNYTNGAYYTNGAYMGNCARMGNCAYGTNGTNGARGTN AGYAARMGNYTNAARCCNGAYMGNGAYTTYAGYTAYGAYGAYACNCARATHAGYAAYACN GARAARMGNYTNGGNGCNAAYATHGCNTCNTCNTAYYTNGAYAARAARYTNAARTAYCCN ACNMGNYTNMGNTCNGTNAGYGAYATHMGNGTNACNCCNACNATHMGNAARGCNMGNGAY AGYATHMGNGCNCARGARATGCARMGNTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MGNGTNGGNCAYACNAAYGARATHYTNGTNYTNYTNGGNGAYAAYTGGTTYGTN GARMGNTCNGCNAARCARGCNTAYCARATHGCNGAYMGNMGNATHGCNGARYTNGAYAAR AAYATHAARGARYTNCARGARCARCAYAGYYTNYTNACNCCNMGNYTNGAYTTYACNTCN GARYTNCARGCNCARTCNAARGARAAYAGYGAYATHAARGARATHGTNGARGARTAYGTN GARGARAARAARAARGARTGGGAYAARCCNCAYMGNGARAAYGTNMGNCAYCAYMGNCAR AARYTNCARYTNCARGCNGCNGAYGTNAARAARAARATHTCNGARAAYATHCCNAGYTCN GAYCCNYTNAARGAYGARGARYTNTCNAARMGNYTNGAYGCNYTNGARCARYTNGARGCN GARMGNGGNGARYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GCNGARACNTCNGCNGCNGARGAYGGN------------AAYTAYGAY CCNGCNCCNGTNAARMGNGCNYTNTGGATGTCNYTNYTNGTNCARGTNGTNAAYCARAGY TAYGTNYTNTCNYTNATHGCNATGATGGCNTGGAGYATHGCNTAYCAYTCNTGGYTNAGY TTYGCNYTNYTNYTNACNGCNTGYTTYYTNTGGATGATGCCNAAYTCNMGNAARTGGTGY YTNMGNGCNTCNCCNTTYATHYTNGTNTAYATGGARATGYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGGGNTAY ATHGAYGARTTYGARATHTAYGCNAGYGAYAAYTGYTCNYTNATGTTYYTNTCNACNAAR YTNAAYGGNGGNGCNMGNYTNATGYTNGCNAARATHAAYTGGTCNTTYGTNYTNAAYGAY GAYGARTTYGARGARAARACNGAYGTNATHATHGGNAGYATHCARAARGAYATHGAYAAR YTNCARAARCARGTNAGYGARGGNYTNAARGAYGCNGGNTTYGTNTCNACNCAYGGN--- ---ATGTCNYTNGCNAARGGNCAYGTNAARGAYYTNGCNCARCARAAY------------ ---------CARGGNGCNGAYYTNTCNGCNYTNAGYCARGAYATGCCNTTYTGGGAYMGN CAYTTYCCNGGNAARAARGARGTNCCNTGGACNGAYTTYMGNGAYAARTTYGTNTTYGAY TAYGARGCNAARATHACNGARGARTTYCCNGARAAYACNGARGARMGNAARCARTTYTTY GTNAAYYTNATGTAYAARGAYGTNTTYAAYYTNAGYAARATHGTNAGYMGNGCNACNTAY AAYAARTTYTGYGAYCARCCNCAYCCNCAYGCNTTYTTYYTNCARATGCARGARTAYGCN ATHGCNTAYATGTCNYTNMGNAAYGTNATHAGYATGGAYAGYAGYYTNMGNATHCCNACN ATHCARAGYYTNGGNCARTTYACNTTYCCNGCNATHGTNTCNGGNYTNACNGAYATGYTN ACNGAYGAYGAYCCNAAYATHMGNGCNGTNGCNGCNATHGCNYTNGCNCAYGCNGGNAAR AAYCARAGYYTNACNGTNGAYAARATHATHAARYTNYTNGARGAYGARGAYMGNYTNGTN MGNGARAGYGCNTGYYTNAGYYTNGGNTAYYTNMGNTCNACNMGNGCNGTNCARTCNGTN GTNGAYMGNTGGMGNYTNGCNYTNAGYMGN---------------ATGGAYGCNCCNGAY GCNCARMGNTGYATGAARGTN---------------------ACNCARATHYTNTCNTCN GARATGAAYGCNYTNAARCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHGAR MGNGTNGARAARGARATHGCNCARTAYGARAGYMGNYTNGARGAYATHGARMGNATGGGN MGNYTNACNAARGTNTCNAARGAYYTNMGNGARCARYTNCARGARGARAARAARTCNYTN GARGARGARYTNAAYAAYCAYCARAAYGARYTNAARGGNYTNMGNTGGGARAAYTGGAAR AGYATGYTNGTNTCNGTNGTNYTNYTNGCNATHGTNTAYACNTTYTAYCAYYTNATHTTY GCNTCNCCNTCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTCNCCNAARGGNTGYGARTCNYTN ATHGGNAAYGGNAARAARCARAARCARTAYTTYTGGCARTAYAAYGTNCARGCNAARGGN CCNAARGGNACNMGNYTNAARYTNGCNGTNGAYGCNCCNAARGAYCCNCAYATHYTNAAY GAYTTYGARGAYCCNGTNTTYGAYGARTGYAAYACNGTNGTNGCNGGNATHMGNCAYGGN GGNAARGCNMGNAARGGNGAYGGNAAYGARATHGCNCCNAAYCCNAARAARYTNTTYGCN ATHGGNCAYCARYTNYTNMGNYTNAGYAARMGNATHAAYGCNTGYCARYTNGGNACNGAY GTNCCNGCNGCNAARMGNAAYGARTCNMGNAARGARAARAAYAARYTNGCNTCNMGNGCN TGYMGNYTNAARAARAARGCNCARCAYGARGCNAAYAARATHAARYTNCAYGGNYTNGAR GARGARCAYAGYCARYTNAAYAAYGTNGTNGGNYTNATGTGGCCNCAYYTNMGNGAYCAY GCNAARACNACNYTNTCNCARGARAAYAARTCNGCNTCNCAYTCNAAYTCNTCNYTNYTN AGYATHYTNGARAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ACNMGNATHYTNMGNGARYTNGTNGTNGARAARGTN GAYGGNGARAARAGYTTYTTYGARATHCCNYTNGAYGAYTCNGTNAAYTCNCARCCNTCN GCNCARGCNTCNYTNGCNCARAAYGARAAY---------GARCAYTCNACNYTNCCNTTY ACNCCNTCNMGNTCNAAYGARATHTCNAARGTNACNYTNTCNTCNACNTCN--------- ---------ACNCCNATHTCNGTNAARAARMGNGGNAARTCNGTNATGATHTCN---ACN CCNTTYAARGARCCNGGNYTNCCNYTNTCNGCNGTNMGNMGNCARAAYGCNAARMGNMGN AARACNACNTGYACNCCN---TCNMGNAGYCCNGTNGARATGYTNGCNATHYTNAARAAY AGYCCNATGGTNGARATGACNMGNMGNAARTCNMGNCAYYTNYTNTCNTCNCCNYTNACN TCNCARGARCARTAYTTYMGNGAYYTNATHTCNACNGARACNTGYMGNYTNAAYATHYTN TGYGAYAARTGGAAYAARACNGTNTGYGAYATHGAYGARYTNACNGARGAYGTNYTNGGN CARATHMGNTCNGTNGTNGGNAARGCNCARYTNYTNATGGTNCARMGNTTYAARCARTTY TCNGGNYTNATHGAYAAYTAYGCNTTYAAYACNGGNGARAARAARACNACNCCNACNGAY YTNCARGGNTTYTGGGARATGATHTAYTTYCARGTNGARGAYATHGAYATGCARTTYGCN YTNYTNGAYGARYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNGCN GARGCNATGGGNGCNTCNGTNGAYAGYACN---GAYCCNGAYATHGAYGARAGYYTNGAR GGNATHGAYGARATHYTNAAYGAYGAYTCNACNCCNYTNGCNCCNAARACNTCNGTNAGY GTNATHCCNGCNGCNTCN------------CCNACNAARCARACNACNTCNAGYACNGAR ------------GCNGCNTCNAAYGGNGTNTCNGARAARCCNGTNTCNGTNACNGAR--- ------TCNGARGCNGAYACNACNAARATHGCNAARCCNGAYGARATGAARAARYTNACN GARGCNGARMGNYTNAARATGMGNGGNGARAARTTYGGNGTNGTNTCNGARCARGCNAAR AARGAYATHMGNGCNCARMGNTTYGGNYTNACNCCNACNGARAAYAARGGNAAYATHATH AGYTCNTCNGARACNACNCCNGAYYTNGARAARYTNAARAARMGNGCNGAYMGNTTYGGN TCNGTNACNTCNACNGCNYTNTCNAARYTNACNGARGARGARMGNAARAARAARMGNGCN GARMGNTTYGGNGTNACNACNATHCCNACNACN---------AAYGTNAGYATHAAYTCN ACNGAYACNGARYTNGARGCNAARAARAARAARMGNGCNGARMGNTTYGGNYTNACNACN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MGNAGYYTNGTNGARACNGCNGTNGCNGCNAARYTNCCNYTNGAYYTNTCNMGN AARCCNGGNMGNATHACNCCNGARCARYTNGAYTCNACNYTNGCNYTNTTYAARGGNAAY TAYTCNYTNATHATGCARCAYYTNGAYACNGTNCARGTNGCNYTNGCNACNAGYCARACN YTNAARGAYCCNTCNGGNMGNMGNCAYGAYAAYYTNGTNGCNAARGARAARTCNYTNGTN CARGCNGTNGCN------------------------GAY---------------GCNGAR GAYACNCCNCCNAGYCCNYTNYTNYTNYTNTCNAARGCNYTNYTNCARGARATGGARGAR AAYAARGAYGARMGNACNATHAGYYTNGAYGGNTTYYTNTGYYTNYTNACNTAYYTNTAY TCNATHTGYGAYGGNAGYGAYGARGAYGGNGAYGARGTNAARATGATGCARGARCAYYTN GTNMGNGCNATHYTNAARACNAARGAYGAYYTNCCNCCNTTYATGCARAAYATHGTNGGN GAYAARGTNAAYGARAGYATHYTNGCNGAYCARGTNGARAAYYTNTGGGGNAARYTNGAY GCNATHTCNCARGGNMGNGARAAYATGTCNCARTTYAGYTCNGTNYTNGAYMGNGGNGAY GCNATGAAYCCNGCNAGYATHAARCCNYTNATGTGYCARGTNATGGARAARGTNYTNGAY CCNGCNAARCCNGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGYTNAARGCN GCNYTNAARACNAAYGAYTGGATHAARATGGAYACNTGGGARTGYGARCARAGYTCNTGG YTNGARACNYTNAARGTNYTNMGNCAYAGYAARCARYTNATHGAYACNCARTAYGGNTCN GGNCAYAARCCNTCNCCNTCNAARMGNMGNMGNAARCARACNGTNGCNGAYYTNACNCAR AAYCARGTNCCNAARATHGARGCNGARGARGAYCAYGGNCCNGTNGTNAARYTNYTNTGY GGNGCNGAYYTNYTNGARTCNTTYGCNGTNCCNGGNYTNTGGTCNGAYGARGAYATHGAR CARATHGTNGGNAAYTTYGGNYTNGTNGTNATHACNMGNTCNGGNTCNGAYCCNYTNAAR ATHATHTAYGARTCNGAYGTNYTNACN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARAAYMGNTCNYTNYTNGCNGAY TTYTTYYTNAGYTGYAGYCARATHYTNTCNCCNTGYGGNCARGTNATHGTNACNYTNTGY AARGGNCARGGNGGNACNCCNGCNGAYCARCCNATHMGNTCNTGGCAYGAYAGYTGGCAR GTNGTNGCNATGGCNACNAAYGCNGGNTTYYTNYTNCARCAYATHATHCCNTTYGAYGCN TCNYTNTAYCCNGARTAYCAYAGYGTNGGNTTYMGNTTYCARGAYAARAGYTTYGAYACN TCNGGNGCNYTNACNCAYATHTTYGARYTNGCNGARTTYGTNGAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATHAAYATHMGNYTNGTNTTYAGYATHATHGGNATGYTNATHGGNGTNTCN GTNGCNATHGTNTTYAGYATHCAYTAYGARAAYTAYAAYGTNGGNYTNTGGGGNYTNYTN TCNGGNATGGCNGCNTCNATHGCNTTYTTYGTNACNGTNACNTAYATGAARCAYTTYTGG GAYCCNTTYCCNCAYCAYYTNMGNAARYTNATGYTNACNGGNTGYTTYATHCARYTNGCN GGNGTNTCNTCNTTYATHGCNTAYYTNGTNYTNGCNATHACNAAYAARCARGAYYTNATH ATHTAYGGNAAYGGNTAYTAYYTNACNTGYGCNTGGTGYTTYATGACNTGGAARTGGGGN TTYGCNYTNYTNYTNTAYTCNMGNTCNTTYYTNTAYTCNTAYATGAGYGAYYTNGAYCCN ACNTCNTAYTCNGARCCNGAYAARTGYGTNATGAARCAYYTNGARTGGAAYTTYMGNYTN GAYTTYGCNGCNACNMGNYTNGTNGCNGARGCNAAYATHACNTTYGARAAYMGNACNTCN GCNYTNTAYCARYTNCCNYTNGAYATHMGNAAYATHGAYGTNCARTCNGTNTTYYTNGAR CCNAGYGAYCARCCNYTNGARTTYAGYATHGAYAAYCCNGCNAAYGTNTCNATHGGNTCN MGNYTNGTNGTNACNYTNCCNGCNATHMGNGAYAARMGNTTYTGYYTNAARTTYAARTAY GTNACNTCNTCNAGYGCNTCNGCNYTNCARTGGYTNAAYAARGAYCARACNGARGGNAAR MGNCARCCNTAYYTNTAYAGYCARTGYCARGCNGTNCAYGCNMGNAGYYTNYTNCCNTGY CARGAYTCNCCNGCNGTNAARTTYACNTAYTCNGCNAARGTNGARGCNCCNMGNCARYTN ACNGTNYTNATGAGYGCNGTNMGNCARGGNGCNCARCCNTCNGARTGYTGYGGNGARAGY YTNACNACNAGYTTYGARATGAARGTNCCNATHCCNAGYTAYYTNATHGCNYTNGTNGCN GGNGAYATHCARGCNMGNGAYATHGGNCCNMGNTCNAARGTNTGGGCNGARAARGARGTN GTNAAYGCNGCNGARGARGARTTYTCNGARACNGARGTNATGYTNCARACNGCNGARCAR YTNATHGGNCCNTAYGTNTGGGGNCARTAYGAYYTNYTNGTNYTNCCNGCNTGYTTYCCN TAYGGNGGNATGGARAAYCCNTGYYTNACNTTYGTNACNCCNACNGTNYTNGCNGGNGAY AARTCNYTNGTNGAYGTNATHGCNCAYGARATHTCNCAYAGYTGGACNGGNAAYYTNGTN ACNAAYGCNACNCAYGARCAYTTYTGGYTNAAYGARGGNCAYACNNNNTTYNNNGARMGN AARATHNNNNNNNNNNNNNNNGGNNNNAGYNNNCAYNNNNNNNNNNNNGCNNNNNNNGGN NNNNNNNNNYTNNNNNNNACNGTNMGNACNYTNACNGCNAAYGGNGARGARCARTAYACN AARYTNGTNACNGAYYTNACNGGNGTNGAYCCNGAYGAYTCNTTYTCNGCNGTNCCNTAY GARAARGGNTTYGCNYTNYTNCARTAYYTNGARACNYTNYTNGGNGGNCCNGARGTNTTY GARCARTTYYTNMGNGARTAYATHGARCAYTTYAARGARCARTCNATHACNACNGCNGAR TGGAARGAYTTYYTNTTYGARTAYTTYCAYTCNCARGARCAYCARGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGTCNGTNGAYATHMGNAGYAGYGARMGNMGNAARTAYAAYGAR YTNCARGCNMGNGARAARGARATHGCNGCNYTNAARGCNTCNTCNCCNGCNTCNCCNAAR GCNYTNCARGARAAYGAYAARMGNATHMGNMGNGARATHGCNAAYAGYAAYGARMGNMGN MGNATGCARTGYATHAAYGCNGGNTTYTCNTCNYTNAARGCNYTNATHCCNCARYTNGAR GGNGARAARYTNAGYAARGCNGCNATHYTNCARCAYACNATHGARTTYATHAAYGCNYTN AARGARAARAAYTCNTGYATGCARAGYCARYTNGAYCAYTCNAAYMGNYTNYTNGCNGAR YTNGGN---CARGAYMGNGTNGTNACNGAYTCNTAYGTNACNAAYTCNCCNCCNCCNTCN AARMGNAARAARMGNGAYACNGARTCNTCNGAYGARGGNGTNGGNTCNYTNTCNGAYGCN TCNGAYGARGGNGGNGTNGARYTNMGNCARGARAAYGARGCNYTNMGNAGYCARYTNAAY GCNGARMGNCARMGNAGYATHTCNYTNGARGARMGNAAYCARYTNYTNGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNATGGARAAYCAYGAR GAYATHYTNGAYGCNYTNACNGCNTTYGGNAARAGYTCNCAR---CARGARATHCCNYTN GTNYTNGARCARTAYYTNAAYTGYGTNGCNAARAAYGGNGARACNYTNTTYCCNTGGGTN CARYTNAARCCNYTNATHGTNGGNAARATGGARCARGTNATHCARGARYTNAARCAYGGN YTNGARTCNGARAGYATHCCNACNMGNCCNAAYGTNGARAAYGTNMGNTTYGAYGTNATG CAYGCNMGNATHATHGAYGCNYTNCAYAARTTYAAYGGNGCNCCNTTYACNATHCARMGN YTNTGYGARYTNYTNACNGAYCCNAARMGNCAYTAYAARMGNAGYGAYAARTTYATGMGN GGNYTNGARAARAAYGTNYTNGTNGTNAGYACNGTNGAYCCNTTYGGNMGNAARGTNGTN TGYGAYTCNTCNAGYAARCAYATGATGAAYGGN---ATG---GAYYTNAAYGGNTCN--- TTYCCNCCNMGNGAYACNGCNYTNACNGTNCCNYTNCCNCCNGTNCCNGGNTGGGTNACN ACNAGY---------CCNTCNMGNGTNCAR---ACNCCNTCNYTNGARTCNACNGCNGAY CARMGNYTNAGYCCNCARACNTCNGTNCARGAYTCNGGNATHGTNTCNAAYGGNATGTCN AGYAGYYTNACN------AGYTCNGTNTTYACNGAYCARGGNGARCAR---YTNGCNGTN CARTCNGARGARGTNGTNGARGARACNGTNGTNACNATGGARACNAGYGARGTNAAYCCN GTNGTNACNGGNGGNGGNGARTCNYTNGCN------GAYGAYGARGAYGARGARATG--- GTNGAYGAYAARGARATGTCNTCNTCNTCNTCNTCNTCNTCNTCNTCNGARGARYTNTCN ACNTCNTCNGAYTCNATHGAYAAYGGNCCNTCNGAYYTNGCNATHGCNATHAGYTCNTCN AAYGARTCNGCNGGNCARCAYMGNCCNTGGGCNTCNATHGTNCARGARGGNAARGARAAR GGNCARACNGAYGGNGARGTNMGNTGYGARGTNTCNGARAARGCNTCNTCNCCN---TCN TCNTCNACNTCNGTNTCNTCNTGYGAYCCNTTYACNACNCCNAAYCCNTCNCCNTCNGAR TCNTCNGTNTCNTCNGAYGTNGAYYTNGARATHACNACNCCNGCNTCNTCNCAYACNAGY TGYTCNTCNGCNTCNCCNGCNGCNGGNACNGCNTCNYTNTCNCAYGARTCNATHTCNACN TCNCCNGAYCCNATGTCNCCNYTNGGNAGYAGYGGNGCNGAYTGYTCNGCNTCN------ ---------------TCNTCNTCNTCNACNTCNGARCCNGAYCAYCCNACNACNTCNTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNAAYTGYYTNGTNYTNAGYYTNTAYCCNGGNAAYGARGGNTAY ACNATHATHYTNCCNTCNMGNAGYGGNGGNGARTCNGARACNATGAARYTNCCNTAYGAR GARTCNGARATHYTNGARTAYATHGAYGCNTGYCARYTNCCNCCNTTYYTNYTNGAYYTN YTNGARAARGCNCCNATGAAYATHTTYTAYAGYGGNTGYATHGTNGTNGARATHMGNGAY TAYMGNMGNTCNGCNATHGGNTCNTAYGGNTCNAARTAYGTNYTNYTNMGNCCNTCNCCN CARTCNATHYTNMGNGAYGTNACNGCNATGAGYTGYGAYGGNCAYAAYTGGACNCARGAY GAYYTNTTYCAYYTNGARAGYGARYTNATHYTNGCNACNGARGARCCNYTNTGYYTNGAY CCNTCNACNGCNGTNATGTTYGTNGARAAYGTNYTNCARTAYGARGARAARTTYYTNAAY GAYCCNGCNYTNAARMGNTCNGTNAARAARTAYACNCARGCNGCNGTNAAYMGNAARMGN AARYTNGCNCARTCNGCNACNCCNAGYGARATGMGNYTNCAYGAYTTYYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR TGYCAYTCNAARYTNAARTAYTCNATGGTNYTNTGGTAYGAYAGYGTNATHAARAAYGGN GARYTNAARTGGCARGAYGARYTNAAYATHAAYAAYGARATGTTYTTYGAYGTNTGYGAY GGNATHTTYYTNAAYTAYTGYATHTCNGARGARAARATGGAYAAYTCNYTNAARAARGCN AARGCNTCNAAYMGNCARTTYGAYGTNTAYGCNGGNGTNGAYGTNTTYGGNMGNTCNACN CCNGGNGGNGGNGGNTTYAAYTGYMGNGARGTNATHAGYATGATHYTNAARTTYGGNYTN TCNTGYGCNATGTTYGCNCCNGGNTGGGTNTAYGARCAYYTNGGNACNGARAAYTAYGAY TTYAAYGARATHAARTTYTGGMGNYTNYTNGARGAYGTNTTYCCNGCNAARTCNATHTCN CCNCCNTTYMGNACNTCNTTYTGYCARGGNAAYGGNMGNAAYTAYTTYATHGARGGNCAR GCNGTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGCNTCNAARAARGTNACNTTYCCN AGYGCNAAYAARCARGGNGARTGYTCNGCNGTNGTNAGYGGNGAYCCNAARACNTGYGAR AARGGNNNNATHGTNYTNCARGARTGGTGGGGNATGAAYCARCARATHCARGAYTGYGGN AARGAYATHTGYCAYMGNGCNAAR---TTYGTNACNYTNGTNCCNGAYYTNTAYMGNGGN AARGTNGCNATHGAYAAYGARGARGCNGGNCAYTTYATGGGNGAYYTNGAYTGGAARGGN GCNGTNGAYGAYATHCARGGNGCNGCNMGNTAYYTNAARAGYCARGGNGTNAARAARGTN GGNGTNACNGGNTTYTGYATGGGNGGNGCNYTNGCNTTYGCNGCNGGNGCNYTNATHCCN GARGTNAGYGCNGTNGCNCCNTTYTAYGGNATHCCNTCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GTN CCNTTYTTYACNTCNGGNYTNGGNATHYTNGARCCNATHMGNGGNGGNACN---AAYCCN TCNGARAARCAYCARCCNCCNCARCARCCNGTNYTNYTNGAYACNAAYAARATGGARGAR AAYAARTCNTCNCAYGTNYTNGAYATHCCNCCNGTNGAYTTYGAYTGGAGYTCNAGYGGN YTNACNAAYCCNYTNAARGTNTTYAARCCNGAYAAYTTYAAYTCNGGNYTNTCNTCNTTY GGNCCNTTYGCNGAYATHYTNCARAARAAYACNACNAAYGGNCARACNYTNAGYCCNGAR GCNATGAGYGTNGTNATGAARATHCCNAAYYTNAAYTTYATGCARTCNAAYGTNYTNATG TTYCCNATHAAR------------------------------------------------ ------------AAYGTNTGYCAYYTNATHGCNGARAGYTTYTGYCARGAYTCNGTNATH GGNGCNGAYAARTTYYTNTCNACNTGGTCNYTNGARGARTGGTGGGAYATHMGNGGNGCN YTNGTNGCNYTNATGAARGARGCNACNAARAARGGNTGGACNAARGAYAARATHATGGCN GCNYTNGGNCARGTNGAYGAYTCNTAYAARAARGTNATHGCNGARGCNATHACNGTNCAY MGNCCNGCNYTNCAYCARAARYTNATHCARGAYACNACNYTNGTNTCNCAYGCNGTNYTN TCNGAYTTYGAYTGGAARYTNCARYTNGCNATGTCNAGYGAYAARATHGCNACNYTNCAR GARCCNTAYYTNCARYTNGAYYTNGAYGTNMGNGARGCNAGYGGNGGNAARAARCARYTN GTNYTNGARYTNGAYAARGAYGARYTNTCNAARYTNATHTCNTCNYTNGARGGNTGYAGY AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYTCNGAYGTNYTNMGNGAYYTNGGNCARGAR GCNAARATGGTNATGYTNCARTAYTCNCARACNYTNGGNGARAGYGARMGNTAYGARCAR CAR--------------------------------------------------------- ------------------------------------------------------------ ------CARGGNGGNCAYGGNCAYGCNCAYAAY---AARCCNYTNCARTTYGCNTCNGAR GTNCAYAAYGCNGARCAYATHYTNGARCAYYTNCARMGNGTNATHGCNACNAARTCNAAR GARGARATGTCNGARGARGARYTNGARTTYCAYTAYTTYAARYTNCAYGAYTAYGAYAAY AAYAAYMGNYTNGAYGGNGTNGARATHGGNAARGCNYTNACNCAYTTYCAYGAYGARGGN GGNAAYGGNAAYGAYGCN---------------GCNAARGARAAYGCNAARGTNTTYGGN GAYGARGARATHTCNAAYATHGTNGAYTCNGTNGTNACNGAYAAYGAYAGYAAYAARGAY GGNTAYATHGARTAYTTYGARTTYAARAARMGNCARACNGARCARAARGGNGCNTCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATHACNYTNTCNATHGARGAYAARGGNTCNGGNGCNAARCARATGACNGCN GCNGARCARGCNGARGARMGNATGMGNYTNGCNYTNAARGCNGCNGCNGCNGCNGAYGAR AARYTNMGN------------------------------GGNCAYGGNATHGGNGAYAGY AARAGYCARMGNTCNAGYCCNGAYCCNACNCAYTCNCARGGNTTYGCNGARTCNGTNGCN GGNATHGARTCNGARAAYTTYGTNCCNTCNTCNTTYAARTCNTCNMGNACNGCNAARGTN AARGAR---CCNTTYGAR---TTYGARACNGCNCAYGAYAGYGCNATHTTYGGNTCNYTN TCNATGAARGGNTTYACNATHAARCCNGAYYTNGAYACNCARCCNYTNGAYYTNGAYCAR GAYTCNATHATHCAYCCNAGYYTNTTYTGYAAYYTNGARGGNAARATGGAYMGNTGGATH GARMGNYTNTCNCARYTNMGNMGNAARMGNYTNGARGGNGARGCNATGATGGAYGTNGTN GTNGTNGGNAGYTGYAAYACNGAYYTNATHAGYTAYGCNTCNMGNYTNCCNAARAARGGN GARACNYTNAARGGNTAYAARTTYTCNATHGGNTTYGGNGGNAARGGNGCNAAYCARTGY GTNATGGCNGCNAARYTNGGNGCNATHGTNGCNATGATHGGNAARYTNGGNAAYGAYACN TTYGGNAARGAYTAYYTNGARAAYTTYCAYAGYCAYGARGTNAAYYTNGAYCAYYTNAAR GTNGTNGARGGNGTNTCNTCNGGNGTNGCNCCNATHAAYGTNGGNGAYAAYGGNGARAAY TGYATHATHATHGTNCCNGGNGCNAAYGAYYTNATGACNTCNAARGARGTNGARACNGCN GARGAYATGATHAARAAYGCNAARGTNYTNATHTGYCARAAYGARATHCCNCARGARGTN TCNYTNACNGCNGCNMGNYTNGCNGGNAARCAYAAYGTNCCNATGATHTAYAAYCCNGCN CCNGCNCCNACNGAYYTNCAYCCNCARYTNTTYTCNATHCCNGAYTTYTTYTGYCCNAAY GARACNGARGCNGARYTNYTNACNGGNATGATHGTNTCNTCNGTNGARGARGCNATGGAR GCNTGYAARGTNYTNCARGAYACNAARGAYTGYAARACNGTNATHATHACNYTNGGNAAR AARGGNGCNGTNTAYAARGARAARAGYGGN---AAYGCNGTNCAYGTNTCNATHAARGAR GTNAARGCNATHGAYACNACN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------ATGATG CARCCNATGATGTCNTCNCCNCAR------ATGCARATG---CARTCNCAYATGAARCAR AAYAARAARYTNATHCCNCARGAYATHCCNAARTCNGAYACNAARGGNGAYAARCCNCCN GTNACNACNGTNTTYGTNGGNAAYATHAGYGARMGNGCNCCNGAYATGATGATHAARCAR ATGYTNCARMGNTGYGGNAAYGTNYTNAGYTGGAARMGNGTNCARGGNGCNTCNGGNAAR YTNCARGCNTTYGGNTTYTGYGARTAYGARGAYCCNGARGCNACNYTNMGNTGYATHMGN YTNYTNAAYGARTGGCARATHGCNGAYAARAARYTNGTNGTNAARGTNGAYGCNAARACN AARACNYTNYTNGAYGAYTAYMGNAAYAARAARAAYAAYGGNGARTCNAARTCNTCNGTN AARAARGARCCNGGNGTNAAYGGNGAYAARAARGAYTCNGGNGGNGAYTCNTCNGTNAAR GARGARAGYAARGARAAYAARAARGAR---GAYGARAARGAR---GAYYTNGAYGARAAY ACNAARMGNGARGAYMGNGTNGCNAGYGCNGGNYTNGARGCNATHATGMGNGARTAYGCN TTYGARYTNGCNAARGARCCNTCNAARTCNTCNGAR---GCNGAYGGNGAYAARGARAAR AGYYTNCCNAARAARGAYAARGAYYTNYTNATGCAYCCNAARGAYACNGGNTTYGAYGAY ATGGARATGGARGAYGARAARMGNGARATHATHAAYMGNGARATHAAYAARTTYMGNGAY MGNCAYAARGAYGAYGAYGARGAYAARGARAARGAY---MGNGARMGNGARMGNAGYATH GCNMGNGARMGNGARMGNMGNCARGARGARAARMGNCAYMGNGARMGNYTNGAYMGNATG MGNGARCARMGNGAYMGNGARTCNTCN---------------GCNAARGAYMGNAGYAGY ACNMGNATHTCNMGNTCNAARTCNMGNTCNGTNTCNCCNGCNCCNCCNMGNTCNMGNMGN MGNTCNMGNTCN------------MGNGAYMGNAGYAGYMGNGARMGNTCNMGNGARMGN MGNAARGARMGNGARATHGARGARGARGARGARYTNTAYGARMGNMGNAARYTNGARAAR AARYTNMGNGARAARGARGCNGCNTAYCARGARMGNYTNAARAAYTGGGARGGNMGNGAR MGNAARAARTCNMGNGARTAYGARAARGARAAYGARMGNGARGARGARMGNAARGTNGAR GARGGNMGNGARGCNMGNMGNYTNAARGARTTYYTNGARGAYTAYGAYGAYYTNMGNGAY GAYCCNAARTTYTAYAARGGNAGYGCNYTNYTNMGNMGNCARAARGARMGNGAYAARGAR AARGARYTNGAYAAYMGNGAYMGNCARMGNGARAARGARGARTTYGARGARATHAARMGN AARYTNTTYGAYGARGGNCAYCCNGAYGCNGARACNGARGTNGCNMGNATGGARMGNGAR MGNGARGARCAYYTNCARCCNMGNYTNCAYYTNCARGARATHAARCARCCNAARCARCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ACNAAYTTYYTNTGGATGATGTAYMGNTGYGGNTGGGCNCAR AARMGNGAYCARGARMGNGTNYTNGCNGTNCARATHAGYAARGCNGGNTTYGARCARATH YTNTCNAARGCNYTNACNACNAARYTNTCNCCNAAYCAR---------GCNGAYAARGAY GARGTNMGNYTNCARTGGGAYCCNGAYCAYGAYCCNTCNGGNAAY---AGYYTNCARMGN MGNGCNATHCARYTNGGNYTNMGNGGNATGGGNAAYTGYATHCAYMGNTGYTTYGGNGTN ATHGAYMGNMGNAARMGNTAYYTNCARTCNAARTAYACNAAYGARCAYGAYTTYTCNATH GARTTYGARAAYYTNATGGARGARGARCCNCARGAYGARATGTCNMGNYTNYTNACNGAY MGNGARMGNCARYTNYTNCARGARAAYCARTTYGCNACNYTNGCNCARGARCARCAYAAR GTNGAYYTNGARGTNGAYGCNAARYTNGCNCAYGARYTNGARMGNGARGARGARGCNTTY TAYGARGCNAARMGNGARGCNGCNCAYATHGCNMGNYTNAAYAARGCNAARGARMGNACN GCNAARAAYAAYYTNGCNGCNAAYAAYGGNGGNAAYAAYGAYGARTGGGARATHGCNGGN GGNGARGAYGAYTTYGARATHTTYYTNGCNAAYGTNAARGCNMGNTCNYTNGCNACNMGN TCNCARGTNAARAAYGGNTCNGGNGAYGCNCAYAGYACNAGYAGYAGYAAYACNCAYACN AARGGNAGYTCNYTNGAYATGGARTGGGAYCAYGARGCNGGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ACNCCNCCNCCNAARATHTGGTGG AAYCARCCNGTNTTYYTNAARGARGCNYTNAARATGGCNYTNMGNCARYTNGGNGTNACN GTNGCNTGYTCNATGGAYGAYCAYCAYCARGARGTNATGCAYTTYTGYMGNGARCAYAAY YTNCARGGNATHYTNGCNCARGARGCNATHTAYACNATHTTYGAYCCNCCNMGNTAYTTY TCNTCNAAYAAYYTNAARYTNACNTAYAARGGNTCNYTNGARACNAARGARTAYATHYTN GAYGARATHGCNAARTGYATGAAYYTNAAYCCNAAYMGNTTYTGYATHTTYGCNGCNYTN YTNGGNAAYCAYATHYTNACNGAYGARGAYYTNGTNCCNTTYMGNGARYTNATG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CARCARGCNGTNTCNGARGCNAARGGNYTNYTNGGN AGYCARGAYTGGATHACNGAYGAYYTNYTNAAYAARATHGARAARAAYGAYTCNYTNATH CAYCARTTYTCNGAYCCNAAYTTYATGAARGCNYTNAARGARTAYCARGTNGAYCCNAAR GCNGCNATGGARAARTAYAARGGNAAYACNGARGTNGARGARTTYYTNATGGARTTYTGY GGNYTNYTNGGNGAYCAYTTYACNAAYATGAAYTCNTCN------ACNGGNAGYAAYGCN AARACNTCNGCNCCNTCNCCNAAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNYTNYTN AAYTTYMGNGCNTCNTCNTCNYTNGCNAARTTYMGNMGNGCNGTNGAYGGNAARATGAAY GARMGNAARCARAARMGNCARGGNMGNAARMGNCARACNACNGCNCAYAARCAR------ ------------AGYATHAAYMGNGGNAAYGGNACNCCNCCNMGNATH---GGNCAYACN ACNTCNCCNGGNGARAARTCNGCNACNCCNAAYGTNTCNAARTCNACNGCNAGYTCNACN GCNATHAAYAAYCARAARAAYAARGAYAARAARAARGAYGCNAARAARAARYTNACNAAR GCNGAYATHGGNACNCCNTCNAAYTTYCARCAYGTNAGYCAYGTNGGNTGGGAYCCNCAR ACNGGNTTYGAYATGAAYAAYYTNGARCCNGAYATGMGNTCNYTNTTYCARTCNGTNGGN ATHCARCCNGGNGAYAAYGTNGAYGARGAYACNGTNGARTTYATHTAYGARTTYYTNGAR AARCAYGGNGGNATHGARGCNGTNCARAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGGCNGAYYTNATHGGNGAYAARMGNYTNYTNAGYAARAARTGY TTYGARGARATHTGYATHCCNGARAARGAYMGNGCNGAYTAYGAYACNGTNGTNGCNAAY GAYGCNYTNCARGGNAARGTNGTNTGYYTNTTYTTYTCNGCNTCNTGGTGYGCNCCNTGY CARCAYTTYGTNCCNYTNYTNAARGARGTNTAYACNGARYTNCARCARMGNGAYAGYCCN YTNGARGTNGTNTTYGTNAGYTTYGAYAARACNAARGAYGARATGATGAAYTAYTAYMGN GAYAARCAYGGNAAYTGGTTYGCNATHAARTTYGGNGAYCCNYTNAARAAYCARYTNGCN GARMGNTAYTCNATHAGYGTNATHCCNAARYTNATHGTNATHCARCCNGAYGGNGARGTN ATHAGYAAYAARGGNMGNAARGAYGTNCARGAYAARGGNATHGTNTGYATGMGNGCNTGG CARGCNGGNYTNAAYAARCAYGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYGTNTCNGGNATGMGNAARGCNTAYAARGGNAAR CARGAYGTNTTYGAYATHGAYAGYYTNGTNGCNAARGARCCNTAYCARCARTTYCAYGAY TGGTTYGARGARGCNMGNGTNACNCCNGARATHYTNGARGCNAAYGCNATGGCNTTYGCN ACNGCNACNAGYGAYGGNGTNCCNAGYGTNMGNATGGTNYTNATGAARGGNATHAAYAAR CARGGNATHGAYTTYTAYACNAAYTAYYTNAGYAARAARGGNCARGAYYTNAAYGARAAY CCNMGNTGYGCNYTNATGTTYTAYTGGGAYGCNYTNAARAARTCNGTNMGNGTNGARGGN GTNGTNAARAARYTNTCNGARAAYGARTCNATHGARTAYTTYCAYTCNMGNCCNMGNCCN AGYCARATHGGNGCNTGYGTNAGYGTNAAR---CARAGYAGYGTNGTNGARTCNMGNGAR GCNYTNAAYAARMGNTAYGAYGARYTNCARTCNAARTTYGCNGAYGARACNGTNCCNATH GARAARCCNGAYTAYTGGGGNGGNTTYMGNGTNGTNCCNCAYYTNTTYGARTTYTGGCAR GGNCARACNAAYMGNATHCAYGAYMGNATHGTNTTYMGNMGNCCNCAYGARGGNGARGAY GTNGAYCCNAARTTYACNCAYCARGGNGAYGARGGNTGGGTNTAYGARMGNYTNATGCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARTCNACN GCNTAYGTNATHGGNGTNTGYTCNTGYAGYTTYGTNGGNGCNGCNATHTGGAAYTAYGAR AAYATGMGNMGNGTNTAYAARAAYGTNTCNCAYGARCARCARACNCAYATHCAYCARACN GARAARGCN------------TTYGAYTTYMGNCARCAYYTNAAYTCNATGTGGTCNAAY YTNGAYAARGGNCARAARGTNGTNTTYGCNATHYTNGCNGCNAAYGTNGGNGTNTGGYTN YTNTGGMGNYTNCCNCARYTNAARAGYACNATGGTNMGNTAYTTYTCNGCNTCNCCNAGY CAYCCNYTNTCNTCNATGGTNYTNAGYAGYTTYAGYCAYATHAGYATHTTYCAYYTNTTY GTNAAYATGTAYGTNYTNYTNTCNTTYGCNCCNGTNGCNTCNMGNATHTTYGGNCAYGAR CARTTYACNGCNTTYTAYGTNAGYGCNGGNACNATGTCNGCNTTYGCNAGYYTNATGAGY CARMGNYTNYTNAARMGNCCNAAYGTNATHTCNGTNGGNGCNTCNGGNGCNATHATGGGN YTNYTNGGNGTNGTNGGNATGATHTAYCCNAAYGCNCARYTNCARATHGCNTTYGTNTCN AGYATHTTYCCNCAYTCNTTYTCNGCNGARTCNGGNATGAARGCNYTNATHGCNTTYGAY YTNYTNGGNYTNGCNATGGGNTGGMGNYTNYTNGAYCAYGCNGGNCAYYTNGGNGGNATG YTNTTYGGNATHYTNTAYGCNAARTAYGGNAGYAARGCNATHTGGGGNAAYMGNGAYCCN ATHGTNAARATHTGGCAYAAYATHMGNGGNAARCCN------------------------ ------------------------------------------------------------ ------------------------------ATHCCNYTNMGNTCNGTNCARCCNCCNACN YTNCCNGARGGNTTYCAYTTYAARTCNGAYAARMGNATHMGNGGNGTNGCNAARGCNYTN GAYTCNACNGAYGTNAARGAYTTYGCNATGACNYTNMGNAGYAAYGCNTCNAAYGCNCAR ACNAARACNTCNACNYTNACNTGYCCNAARCCNTTYAARYTNACNAARAGYATGTCNGTN YTNCAYGGNACNAARTAYCARTCNGTNGCNGARAARYTNGTNGCNTTYCAR---MGNTCN AARTCNCARACNAARAARTCNAGYYTNTCNAAYAARYTNMGNCCNGARTCNCCNGGNYTN ACNGTNCCNAARACNCCNAARYTNACNACNMGNGGNMGNTCNMGNCCNYTNCAYGCNYTN TCNMGNAARGARCARGARGARATGGARTAYGARGARCARCARAARAGYCARTTYAARGCN CAYCCNGTNAAYACNAARATHYTNGCNYTNMGNGAYGTNGGNGTNCCNAARYTNAAYGCN AARCCNCAYACNGTNATHAARGARTTYAAYYTNCAYCARAAY---GCNCAYTCNCARAGY TGYTCNAAYYTNCARGARMGNGCNAAYGARGCNAARGARTTYCAYGCNAARCCNGTNAAY AARAARATHYTNCARGGNCCNACNGGNGTNAARCCNGTNGARTCNCARCCNYTNACNGTN CCNCARTCNCCNGCNTTYGCNYTNMGNAAYMGNGTNMGNATGCCNATHAARGTNYTNCAR CARGARGARGARACNYTNGCNCCNCCNAARCAYCAYGTNCCNCAYGTNGGNATHCCNTTY CARCCNCARYTNGTNCAYAARCAYACNATHCCNAARCCNTTYAGYGTNGARGARMGNAGY MGNCARATGYTNCARMGNAARGARCARAARATHCARCARGTNTAYGARACNGARAARAAR GCNMGNGARTTYCAYGCNCARYTNATGCCNGGNGAYGARCCNGAYGARYTNCCNCCNAAR CARACNAARCCNCCNACNGARATHCARCCNTTYCARYTNGARGTNGAYCARMGNGGNCAR AARTAYAARGARGARCARAARGTNAARCARGTNCARGARGARGAR------ATGAARGTN TCNTCNGARTTYTAYGCNMGNCCNAAYAARGTNGTNTTYATGGAYCCNTTYAARCCNGAR AARTCNACNAARGCNYTNACNGARGTNAGYAGYTTYGAYYTNAAYACNGAYGTNMGNGCN CARCAYMGNGARACNTTYACNCARCAYYTNAARCARMGNGARGTNGARATGGARGCNATH AARMGNCARAAYGTNGARAARTGYGARYTNGARGARAAYACNGCNGTNGCNATGYTNMGN CARAARATGGTNCAYAARGCNAAYGGNGTNAARMGNTAYAARTGYGTNYTNGTNCAYCCN AGYGARAARTCNYTNACNGARCCNCARTCNCCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TTYTGG CCNMGNTAYGGNGARTAYYTNTAYGTNCCNGTNCARMGNTGGYTNCAYTCNYTNGARCAY GGNGCNATHGTNTTYYTNTAYCAYCCNTGYGCNGARYTNGARGAYATHGARAARTTYAAR GCNATHGCNAARGGNTGYYTNMGNAARCAYATHATHTCNCCNTAYAARCARATGCCNTCN GGNAARAAYTTYGCNATHATHTCNTGGATGTGYAARYTNYTNYTNCCNCARCCNGAYYTN YTNCCNATHGTNCARTTYGTNMGNAAYCAYGCNYTNAAYTCNCCNGARGCNAGYGTNTTY GCNGAYGGNCARTAYGCNYTNGCNYTNAARGARCCNGCNCARATGGTNTCNGAYAARTAY GARTCNCARYTNTGYCCNMGNATGTTY--------------------------------- ---------GTNAAYGARGTNYTNGTNCCNGARYTNGAYGAYGCNATHATHMGNATHGCN AAYATGMGNAARAARCARCCNCCNAARTGYCARAAYYTNTCNYTNAARGCNGCNTCNAAY ACNGTNAARTAYTAYAGYCARGTNAAYGTN------------------------MGNATH AARTGYAAYAARAAYCARATHYTNGTNGGNGGNMGNAARTTYGARTCNGCNACNGAYGCN YTNYTNACNTAYYTNAAYCARTTYGGNTCNTCNCARGGNCARAAYGGNGTNAAYGTNATH GGNAGYGTNGGNACNGCNCCNTCNTGYGAYGGNAARAARTCNTCNYTNGARTCNAAYGGN YTNMGNYTNGARGARAAYGARGARGAYGTNGARAARYTNYTNACNTCNAARGTNTCNCCN GARYTNAARGARGARGTNACNGAYGCNYTNMGNGARGTNAARYTNMGNCAYYTNYTNAAR MGNGCNGCNGTNAARTCNCARAARTCNACNAARACNGGNYTNCARCARGARGTNGARGCN GCNYTNGCNMGNTCNGCNAARYTNYTNGARAARGTNGTNMGNGARGAYATHATHGCNGCN YTNAGYGAYYTNAGYYTNTCNACNCARGCNYTNYTNGCNGAYTCNGCNYTNTCNAAYTCN AAYTCNYTNTCNAAYAAYTCNGAYCCNTCNGAYATHYTNCARMGNGTNMGNAGYMGNTCN ATHTCNCCNCAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATHACNAAYAARTCNCAYMGNAAYTTYTCN ATHTCNGTNMGN------AARYTNGAYGGNGARTCNACNTTYGGNTTYCCNGGNMGNGAR GGNCARGTNGCNTGYAGYACNTCNAAYAARGTNTAYGTNTTYGGNGGNGTNGARCARGGN CARGGNAAYGARCCNAARGARACNAAYGARYTNYTNGTNTTYGAYATGGCNACNYTNAAR TGGTCNAARACNACNGTNYTNGGNTGYTCNCCNCCNTCNMGNTCNGCNGCNTCNYTNGTN GCNGTNGGNACNGARYTNTAYYTNTTYGGNGGNYTNAGYCAYATGTGYGGNTGGTTYGAY GAYGTNCAYATHTTYGAYACNGTNACNAAYACNTGGTCNATHYTNGARACNGARGGNATH AARCCNMGNGCNMGNGAYAARYTNCARGCNGTNGCNATHGAYTCNAAYATHTAYTAYTTY GGNGGNTTYGGNCCNAARTCNGAYGARGCNGARGTNGAYGAYYTNGGN------GGNGAR GAYGAR---GARGAYTTYGARGAYATHCCNGARTCNCAYGARCARGAYGGNGCNGARTTY GGNTGGTTYAAYGAYYTNTGGATHYTNAAYACNGTNACNYTNAARTGGTCNCARCCNATG CARATGAAYYTNGGNGTNCCNACNCARMGNGCNGCNCAYGGNATGTGYGCNATHGGNMGN AAYYTNGTNATHTTYGGNGGNMGNGAYGTNGARGAYMGNCARAAYGAYATHCAYATHTTY AAYATHGAYACNMGNAARTGGGCNACNGAYYTNCARATHTGYGGNGARCCNCCNAGYCCN MGNTCNTTYCAYAGYYTNACNACNGTNGGNGGNAARGCNGTNGTNTAYGGNGGNMGNGGN MGNGAYAAYAAYCAYTTYGCNACNTTYGAYATHTTYGAYYTNGAYAARAARGARTGGATH CCNACNAGYATHGARGGNCAYAARCCNGCNGGNMGNGGNCARCAYAGYACNGTNTGYGTN GAYGAYTCNYTNTTYATHTTYGGNGGNTCNGGNAAYTTYAGYCCNGARATHATGCARTGY CARTCNTTYTAYACNGAYGCNTTYATHATHAARGCNGTNGAYTTYGGNMGNGARAGYATH ACNACNAAYGGNGCNCCNGCNGTNACNTGGMGNCCNATHGGNGGNGTNATHGAYYTNTAY GTNYTNGTNGGNGAYACNCCNTCNGARGTNATHACNCARTAYTGGTCNGTNATHGGNMGN CCNTCNYTNCCNCCNTAYTGGGGNYTNGGNTTYCAYYTNTGYTCNCARMGNTAYGGNTCN GCNGGNCARACNYTNGAYGTNGTNGAYMGNATGMGNMGNCARGGNATHCCNCARGAYTGY GGNATHTCNAAYACNGCNGCNGCNGGNACNTAYGCNCCNTTYTCNYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHACNGAYTTYATHAAYATHYTNAARMGNTAYTAYAARTCN GCNGAYGTNMGNATGGAYGARYTNGARGAYCAYMGNATHGCNACNTGGMGNGAYGTNYTN AARGARAARCARMGNTCNTTYGTNTCNATHAGYCCNGAYGCNAGYYTNTTYGARGCNGTN AARACNYTNATHGAYTAYMGNGTNCAYMGNYTNCCNGTNATHGAYGARACNACNGGNAAY GCNYTNTAYATHYTNACNCAYAARMGNATHYTNMGNTTYYTNCAYATHTTYATHAARGAY YTNCCNYTNCCNTCNTAYATGAARAARTCNATHAARGARYTNGGNATHGGNACNTTYGAR AAYGTNGTNACNACNAGYYTNGGNAGYCCNYTNATHGARGTNYTNAAYCARTTYGCNGAR CAYMGNATHTCNGCNYTNCCNGTNGTNGAY---TCNTCNGGNCARGTNTGYAAYATHTAY GCNAARTTYGAYGTNATHAAYYTNGCNTCNGARAARACNTAYAAYAAYYTNGAYATHACN YTNGGNGARGCNATHGAYCARMGNCARGCNGCNCCNGAYAARMGNGCNGAYAARGTNGCN AARTGYYTNTCNACNGAYAGYYTNGARCAYGTNATGAAYACNATHGTNAARGCNGARGTN CAYMGNYTNGTNGTNGTNGAYGARTGYGGNGGNGTNGARGGNATHGTNTCNYTNTCNGAY YTNYTNAAYTAYACNGTNYTNMGNCCNATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GARAARACNTTYGGN TGGACNGCNCCNAGYCARCAYGAYAARCARCARYTNCCNGTNTCNTAYYTNGGNAARATG YTNGARGGNTTYTGYYTNTCNTCNAARCARTTYATHCCNGGNAARAARTTYCCNCCNCCN GCNYTNCCNAARCAYTTYMGNCCNATHCAYTGGTTYMGNAARMGNMGNACNAAY---GAR TCNGARCARACNGCNGARGAYGCNMGNAARATGACNGCNGTNGAYMGNGGNYTNYTNYTN GGNGARACNCCNATHATGGAYTCNGTNTTYGAYYTNGTNGGNGARAARGARAARGCNMGN ATHTCNGCNACNAARGARGCNATHGCNATGACNCARTCNYTNMGNTCN------GCNCAY ACNCARTCNGARATHACNGTNGARGARGARAARACNGARGCNCAYGTNYTNAAYTCNGTN GCNAARACNYTNAGYACNAAYMGNAGYAARGAYACNGCNATGCCNMGNTTYATHCARAGY TCNACNYTNGTNGARAAYTCNTCNAAYGARAAYAARGTNGARGGNAARAGYGGNAAYGAY GCNGCNGCNCCNYTNTTYCARGGNTCNATGAGYTTYCARCCNTTYMGNAARGAYCCNGCN AARCARGCNMGNTAYGAYAARTAYYTNGCNYTNGTNAARCARAGYGTNTCNGAYCCNTAY GCNCARGTNATHAGYAGYCAYYTNACNGARTGGGARAARTCNMGNGARMGNGAYGARTTY AGYATGGCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYAAYGGNATHMGNTAYTCNTAYGAYGTNACNAARTGYATGTTYAGY GCNGGNAAYATHAGYGARAARYTNMGNGTNGCNAAYTTYGAYTGYAARGGNCARGTNGTN GTNGAYYTNTAYGCNGGNATHGGNTAYTTYACNYTNCCNTAYYTNGTNCAYGCNTGYGCN CARCAYGTNCAYGCNTGYGARTGGAAYCCNGARGCNGTNYTNGCNYTNMGNGARAAYYTN GAYATHAAYGGNGTNMGNAAYMGNTGYACNGTNCAYGARGGNGAYAAYMGNCARYTNCAR YTNTCNAAYGTNGCNGAYMGNATHAAYYTNGGNYTNATHCCNAGYTCNGARAGYGGNTGG CCNGTNGCNGTNMGNYTNYTNAARCARAGYGGNGGNATHYTNCAYGTNCAYGGNAAYGTN ACN------------------------------------------------------TAY GAYGAYTAYAARATGATHAAYTGYGGNATHGGNTTYACNAAYATGTGYGCNMGNACNACN AARGGNAGYTCNGAYYTNAARMGNAAYGARATHAARGARGGNGGNGARATHYTNAARAAR AARATHATGAARTAYAARCCNAARATHGCNGTNTTYAAYGGNAARGGNATHTAYGARGTN TTYAGYGGNAGYAARGAYTTYTGYATH--------------------------------- ------------------------------------------------------------ ------------------------------YTNTCNGCNACNCCNTAYTAYATHCCNTCN GGNACNATHCCNTCNYTNGARCARYTNAARGARYTNGARGCNCAYATHAAYGGNATGCAR GCNGARMGNAAYAARMGNTAYAGYGARTTYACNGARYTNAARGARAARATHTCNCARYTN TAYATHGARATGGCNTCNGAYCCNGAYACNTCNTTYAGYMGNGAYGTNYTNAAYGGNGAY GARGAYTCNTTYAAYYTNTCNATHGCNAAYATGGARAAYYTNMGNCAYYTNYTNAGYAAR YTNCARGARAAYAAYMGNYTNGTNAARMGNCARGTNGARGAYYTNTGGTCNCAYYTNMGN GCNYTNTGGAAYMGNYTNGARACNCCNGAYATGGARMGNGARGCNTTYGARYTNAAYAAR GTNGGNCAYGGNAAYMGNGTNGTNACNGCNATHAARGCNGARATHGARYTNTGYGARCAR YTNAARTTYAARAAYATHMGNAARTTYGTNGAYGGNATHMGNYTNGARYTNGTNTCNTGG TGGGAYAARTGYTTYTAYAGYACNGARCARMGNTAYTCNTTYAARYTNTAYTCNGCNCAY GARTTYACNGARTGGYTNYTNGARGCNCAYGARAARGARYTNGARGARATHAARMGNTAY TTYAAYGAYCAYMGNGARGTNYTNGARAARYTNGCNCARMGNGARGARYTNTTYAARAAY ATGATHGTNTTYGARGARMGNGCNAGYGAYCCNAAYMGNTTYTTYAAYGAYMGNGGNGGN AARYTNYTNCARGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGGARAARGCNGTNGARAAYATHGARGCNATGTTYAARAARGCN GARGCNGAYYTNGAYTAYATGTCNATGAARYTNGARTAYCARYTNGCNGAYGCNGARGGN GCNGGNCCNCARYTNAAYCCNGTNAARYTNATGAARAARATGGTNGAYATHAARCARGAR TAYGCNAAYGTNGTNCARGARTCNAARGCNATHCARGARGCNCARAARGARTTYTCNGAY TAYTTYAARAGYCARYTNYTNGTNYTNACNGARATGYTNAARTCNGTNGARGTNAARACN AARCARGCNCCNGARTCNGAYGCNGAYACNGARGARGTNGGNGARCARYTNTCNAARYTN YTNGGNATHCCNGTNAARGAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARMGNYTNATHGGNMGNATHATGGARACNGARGCNTAYYTNGGNYTNGAR GAYAARGCNTGYCAYAGYTAYAARGGNAARMGNACNCCNMGNAAYGARGCNATGTTYATG GARCCNGGNACNGCNTAYGTNTAYAAYATHTAYGGNATGTAYTGYTGYYTNAAYATHTCN GGNAARGGNGAYGGNGCNGCNGTNYTNATHMGNGCNYTNGARGCNATHGARGGNAARGAY YTNATG---------MGNGCNAARMGNCARGCNAAR------GGNMGNAARCCNATGAAR GAYTCNGARYTNACNAAYGGNCCNTCNAARYTNTGYCARGCNATGGARATHTTYAARAAY GAYTTYAAYAARYTNGAYYTNACNTCNTCNGAYYTNYTNTGGYTNGARGARGGNGARACN GTNGAYCARTCNCARGTNGTNAGYTCNGCNMGNATHAAYATH------------------ ------------------------------------------------------------ ---------------------------------ATHGTNTGYTAYTAYACNAAYTGGGCN CARTAYMGNGAYGGNCCNGCNAARTTYGARCCNGARAAYATHAAYCCNGARYTNTGYACN CAYATHCAYTAYGCNTTYGCNAARATGACNGARGAYGGNATGATHGCNCCNTAYGARTGG AAYGAYGARAGYACNGAYTGGATGGTNGGNATGTAYGCNAARGTNAAYAAYTGGAARAAR AGYAAYCCNGGNYTNAARACNYTNYTNTCNGTNGGNGGNTGGAAYTTYGGNACNMGNYTN TTYACNAARATGGCNGARTAYCARGARAGYMGNMGNAARTTYATHCARGGNACNATHACN TTYYTNMGNAARTGGAAYTTYGAYGGNYTNGGNTAYGAYTGGGARTAYCCNGGNAGYMGN GGNAGYCCNCCNGARGAYMGNCARAARTTYACNYTNYTNATHCARGARACNGTNCARCAR TTYGAYGARGAYGCNCARAARACNGGNCAYCCNNNNYTNYTNGTNAGYGCNGCNGTNTCN GCNGGNAARGAYACNATHGAYATHGGNTAYCARGTNGAYAARATHGCNAGYCAYYTNGAY TAYGTNGTNYTNATGAGYTAYGAYTTYTTYGGNGCNTGGGAYTCNGTNACNGGNCAYGTN AGYCCNYTNTAYCCNCCNAARAGYCCNACN---CCNAARGARGCNATHTTYAAYGTNCAR TAYGCNGCNAAYTAYTGGGTNAGYAARGGNTGYCCNAARAAYAARYTNATHGTNGGNYTN ATHGCNTAYGGNMGNTCNTTYACNYTNACNAGYACNTCNGAYACNGGNATGAAYGCNCCN TCNMGNGGNCCNGGNCARGCNGGNMGNTAYACNMGNGARGCNGGNACNYTNGCNTAYTAY GARATHTGYGGNATGATHCARGCNGGNGCNAARATHGTNMGNYTNGARGAYCARAARGTN CCNTAYYTNGTNYTNGGNGAYCARTGGGTNGGNTAYGARGAYMGNGARAGYATHMGNATH AARGCNGARTAYGTNMGNGAYCARGGNTTYYTNGGNGCNTCNGTNTGGACNTAYGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHYTN TCNCAYATGGCN------------------------------------------------ ------------------------------------------------ATGTCNACNCCN TCNGAYCARACNTCNCARAGYYTNGAYGTNTCNTCNTCNGTNTCNCCNMGNAGYAAYGGN GAYGGNMGNCARYTNCCNAGYATHCCNAAYTCNGCNGTNCAYAAYACNACNYTNGTNAAR GGNAGYAAYAAYACNGCNTCNAAYAGYGGNAAYAARGGNAGYAARGGNTAYGGNCCNTTY TTYCARGARTAYTCNYTNATGGCNGARTAYAAYCARGTNCAYCARCARAAYATHCCNGGN YTNTAYGTNATGCCNTGYTGYAARTCNCCNYTNGTNTGGTCNGGNYTNATGTTYATHMGN CARGGNYTNTAYCARGGNGGNGCNYTNMGNTTYATHYTNACNATHCCNGAYAAYTAYCCN GAYGGNGAYTGYCCNAARYTNGTNTTYGARTAYCCNGTNTTYCAYCCNYTNGTNGAYCCN GARACNGGNGARYTNGAYGTNAARMGNGCNTTYCCNMGNTGGMGNMGNAAYATHCAYCAY YTNTGGCARGTNYTNYTNTAYGCNAARAARATHTTYTAYAARATGGAYACNAARGCNCCN YTNAAYCAYGARGCNGCNGTNYTNTAYGAYCARGARCCNGARYTNTTYAARGGNAARGTN GCNGARTCNYTNAARGCNTCNAARGARMGNYTNTAYGARACNCCNGCNYTNGAYGAYCCN YTNGCNYTNMGNTTYAGYCCNTGGAAYGARTCNGCNCAYCCNGAYGCNAARMGNCARATG ATHAAYACNAGYAARAAR---GAYGTNGAYGAYACNTCNGCNAAYCCNTCNGAYYTNGGN YTNTCNTGGATGAGYTCNAARTCNCCNGARATHTTYTCNMGNGAYGAY------------ ------------------------------------------------GARTAYGTNAAR CCN---------------------TAYTCNCAYATHAAYGAYAARMGNMGNMGN------ ------------------------------------------------------AARTAY ---------------------------------GCNGGNATGGTNTCNGCNYTNGAYGAR GGNATHGGNAAYYTNACNAARGCNYTNAARGAYATGGGNATGTGGGARAAYACNGTNTTY ATHTTYTCNACNGAYAAYGGNGGNCARGTNCAYGARGGNGGNAAYAAYTAYCCNYTNMGN GGNTGGAARGGNTCNYTNTGGGARGGNGGNTTYCAYGGNGTNGGNTTYGTNGCNGGNGCN AAYYTNAARCAYCARGGNGTNGTNAAYMGNCARYTNATHCAYGTNACNGAYTGGTTYCCN ACNYTNGTNAAYATHGCNGGNGGNAAYYTNAAYGGNACNAARCCNYTNGAYGGNTAYGAY CARTGGAAYACNATHAGYGCNTCNGCNCCNAGYCCNMGNAARGTNYTNYTNCAYAAYATH GAYATHATGTAYGCNAARAARGGNGARMGNYTNTAYAAYGAYACNTTYGAYACNMGNGTN MGNGCNGCNGTNMGNGTNGGNGAYATGAARYTNATHACNGGNGAYCCNGGNCCNGGNACN TGGGTNCCNCCNCCNGAYGGNMGNCCNGARAAYGTNGAYGAYGCNGCNAARAAYGTNTGG YTNTTYAAYATHACNGCNGAYCCNAAYGARCAYGTNGAYYTNTCNAAYCARATGCCNGAY ATGGTNMGNAGYATGYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CARCAYMGNYTNTCNGGNCARAGYTAYGARTCNGGNGTN TCNTCNMGNCARAGYTAYCAYAGYACNTCNAGYTCNAGYCAYGGNAGYYTNGAYMGNYTN GARGAYCCNGGNYTNCCNTCNACNATHAAYGTNATHCARYTNTTYCARGCNGGNGTNCCN GAYTCNGARGTNYTNCAYGCNTGGYTNCAYGAYATHAAYTTYGARGARTAYTAYCCNYTN TTYATHCARGCNGGNTAYGAYATGCCNACNATHTCNMGNATGACNCCNGARGAYYTNACN GCNATHGGNATHACNAARCCNGCNCAYMGNAARMGNYTNAARACNGARATHGGNMGNYTN CAYATHCAYGAYGGNATHCCNGAYTTYMGNCCNAAYGAYYTNATGGAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGGTNGARGCNGAYGTNTCN CCNGGNGAYYTNGAYCCNGAYATGMGNGCNGCNYTNCAYAGYATHATGGARGARYTNGTN GAYGARGTNTCNYTNGGNYTNTGYTTYGARATHCAYMGNTCNTGYAARATHGGNTCNYTN TTYATHAAYGGNTTYGAYGAYATGTCNGAYACNGARTAYGCNATHGTNGARMGNTCNGGN GTNGAYGTNYTNGGNCARGTNGCNTCNAARAARAAYTAYGARTGYGTNTGYCCNAAYTGY CARMGNCAYYTNGCNGCNTCNMGNTTYGCNCCNCAYYTNGARAARTGYATGGGNATGGGN MGNAAYTCNTCNMGNATHGCNAGYMGNMGNATHGCNAAYAAYCARAARAAYGGNAGYGAY GAYAGYGGNCARGAYGAYGARAAYGAYAAYGAYTGGAAYTAYGCNCCNGARTCNMGNMGN YTNMGNAARYTNAARAARGAYAARACNGCNAAYTCNACNMGNAAYMGNMGNYTNGCNAAR YTNMGNAAYGGNGGNTCNGGNCAYGARGTNACNACNGCNGTNTCNGCNACNGAYTCNCAY TCNCAYGARGGNAAYGAYCARGTNGTNCCNAAY--------------------------- ------------------------------------------------------TAYGAR TCNATGACNYTNGARGARMGNAARGCNYTNYTNYTNACNAGYTGYGGNGTNATHTCNGAR CAYACNAARAARATGTGYACNMGNACNGGNAARTGYGTNCARCAYACNGAYGARCARMGN MGNCARGTNMGNCARTCNYTNYTNMGNCARAGYMGNGCNCAYGARGTNGARGAYATHCAY ATHGAYATHGAYACNTAYGAYGAYGCNGARTCNCARTCNYTNMGNGARTCNYTNCAYTGG GARGCNTCNTCNAAYTCNTCNCCNGCNGAYTCNACNTCNACNATHAAYAGYGCNTCNGGN TCNYTNAARMGNGCN---------------GTNYTNGGNYTNCCNAARTCNAGY------ AGYAARAGYAARAARATHAARACNGTNAARGCNTGYCARTCNAGYTCNAGYAGYGCNAGY AGYAGYACNAARGARCARGCNATHAAYYTNTAYGAYTTY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TAYACNTCNAGYTCNTGGMGNAAY GCNGCNATHATHGGNGCNATHTAYGGNGGNATGGCNTAYCAYMGNMGNTAYCCNCAYMGN GGNACNATGCCNCCNATHTGYACNAAYGAYTAYGARTTYMGNCCNGAYGGNMGNMGNATH GGNTAYTTYATHTGYCCNMGNATGAAYGAYATGGCNYTNGAYATHTAYTGYTGYGGNYTN MGNAARCAYGARCAYTGYTGYAAYTAYACNATGGCNCARMGNTAYTAYGGNACNCAYCAY TCNACNTCNGGNGGNYTNACNGTNGGNGGNTTYATHGGNATHATGGTNGGNATHGTNGTN GTNGTNGGNATHATHATHTTYTGYTGYTGYAARAARCARCARTCNGGNGTNGTNGTNAAR AARCCNTCNAARGGNGAYGAYGAYGGNCARYTNATGATGTCNCCNCCNCCNCCNTAYGAY CCNCARCCNTAYCARCCNAARGGNMGNAGYGGNAGYATHATGTGGTGGGGNGCNGARTAY MGNGTNAARYTNGTNMGNCCNACNTAYCAYATGCCNTAYAAYAARGGNACNAAYCCNTAY TAYAARATHGAYACNYTNATHAARYTNTTYACNAAYAAYTAYCCNATHAAYYTNGGNYTN YTNTAYTTYTCNGAYCCNGAYGARACNGCNCAYAARTGGGGNCCNGARTCNCCNGARGTN ACNGARCARATHAARMGNGCNGAYAAYYTNACNGGNTAYYTNYTNCARGARYTNMGNMGN ATHGGNYTNYTNGAYGAYYTNAAYYTNATHATHACNAGYGAYCAYGGNTTYGTNTCNGTN TCNAARGAYMGNYTNATHAARYTNGAYGAYTTYGTNAARCCNGARTGGTTYATGGTNGTN CAYTAYACNCCNGTNGCNTCNATHATHCCNCAYCCNGGNTAYGARGAYACNGTNTAYAAY AAYYTNAARAGYGCNGCNCCNTCNAAYCAYTTYMGNGTNTTYAARAARGCNGARATHCCN GARGARTGGCAYTAYAARCAYAAYATHMGNGTNCCNCCNATHACNGCNATHGCNGAYYTN TCNTAYTCNTTYYTNATHAAYATGACNGCNGAYAARTTYGTNAGYGCNGGNATGCAYGGN TTYGAYAAYGCNCAYCAYGARATGTAYCCNTTYTTYATGGCNATGGGNCCNTCNATHAAR TCNGAYTTYAARGTNGAYATGTTYAAYAGYGTNGAYATHTAYCCNTTYATGTGYAAYYTN YTNCAYYTNAARCCNAAYCCNCAYAAYGGNAGYYTNAARATHGTNTCNCARTTYYTNGAR GGNCAYGARACNACNYTNTGGACNTTYTCNACNTAYATHTTYTGYYTNATHATHATHGCN AGYGTNGGNGGNGTNTTYGTNGTNGCNCCNTGYMGNCAYCAYMGNTAYYTNAARCCNAAR YTNAAYCARYTNMGN---------------------TTYGARATHMGNACNYTNTGGAAY GGNGARTGYYTNTGYCAYGAYCCNGTNMGNATHTCNYTNGCNCCNACNCCNGGNGGNGAY GTNCARATHAARGTNCAYGCNCCNTTYTTYAAYAGYCCNGAYAARCCNGAYGGNCCNCCN GGNAARCCNTTYCCNCARYTNTGGGAYTAYGARGTNGTNGARGCNTTYTTYYTNAAYGAY CARGAYCARTAYYTNGARATHGARYTNAGYCCNCAYGGNCARCAYYTNYTNYTNYTNYTN AAYGGNMGNMGNAARATGGTNAARGAYGARYTNGCNYTNACNTAYAGYGCNAARATHGAY GGNGAYACNTGGACNGGNGARGCNGTNATHCCNAARTCNTAYTTYCCNCCNTCNGTNACN AARTTYAAYGCNTAYGCNATH--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MGNGARTCNAARATHMGNCARGAR AAYTAYMGNTCNGCNGARGARYTNATHCARGARGAYGARACNAARAGYAARAAYAAYGAY MGNGTNMGNYTNATGGARAAYMGNYTNAAYGGNYTNAGYAAYTCNGTNGARYTNYTNATG MGNAARYTNGAYTCNAAYGGNMGNMGNYTNAGYGTNTCNATGAAYCARGARAAYACNGGN AAYACNATGCARGARCARATGYTNCARATHCARAAYCARTCNATGATGYTNAGYTTYGGN CAYGTNGTNCARTCNYTNACNMGNCARCARGGNGAYATGCARCARYTNCARTCNAGYTTY TCNAGYATHCARTCNATHMGNAAYGARCAYTCNMGNYTNMGNCAYGGNGARGCNCARACN AARTCNGGNAAYAARGARGARGGNAAYACNYTNTTYGAYTCNYTNMGNGAYACNATHTAY ACNGARGTNGCNTCNYTNATHTCNCARAAYGARAAYMGNCCNCAYTTYNNNCCNAARTGG GGNGARGGNGCNTTYYTNGCNTCNGARCARYTNATGMGNAARAARGGNGCNAGYGARGGN GGNGCNATGGCNAGYACNCARYTNGGNATGGAYYTNMGNTAYACNGAYGCNCCNAGYAGY ACNGCNGCNGAYCARGCNAGYGARAGYTCNYTNTCNGAYATHCCNTAYCCNMGNATHGAY ATGAARCARYTNGAYMGNCARATHAARCARGTNATGATGGARACNATHCCNATHGTNAAR GARCAYATGAAYAAYGTNTGYTCNCCNCARYTNYTNGCNTAYGTNAARMGNYTNATHYTN TCNYTNACNGGNCARACNGGNAGYCARGARTTYGCNMGNTTYTTYCAYMGNCARYTNTCN TCNATHYTNCARGAYACNYTNGARAARTAYGARGGNMGNMGNATGAGYGAYTGYGGNGAR GAYYTNYTNGTNGARATHTCNGAYGTNYTNTTYAAYGARYTNGCNTTYTTYMGNYTNATG CARGAYYTNGAYGAYCCNAAYGTNGTNGAYAARATGAARMGNGARACNCARTCNGCNCAR AAYTGGCARAARAARGARGARGARCCNTTYAARGAYAGYAGYTCNGGNGAYGARGAYGGN GAYGAYGAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNAAYGCN GAYTCNATHTGGAARAARTGYTTYGTNGARGCNATGTAYTTYCAYGARTCNTCNGARAAY GARAARAARGCNYTNCARGAYGTNGTNAAYCAYYTNCARGARYTNTGYAAYAARAARGAY AARTAYATHCARTCNACNAARATGATHATHAARTTYMGNGARAAYACNATHCARAAYYTN CARAARCARAAYCCNTCNAARACNGARATGGARMGNGAYGARYTNGTNAARACNYTNMGN GARGARATHAAYGTNYTNMGNCAYCARATGGAYTGYAAYCCNCARYTNGCNAARTAYTCN GGNGARAAYAARCAYYTNMGNAAYGARYTNAARCARYTNMGNGCNMGNGAYTCNYTNAAY GAYGTNYTNAGYGAYGCNAGYMGNATHGCNGARYTNGARAARYTNTTYAARGARYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARATGGAYYTN TAYGCNATHMGNAARGGNGAYGGNGTNAARAARCCNMGNCCNGTNAGYGCNTCNAGYYTN CAYGAYGCNGAYACNATGMGNTCNMGNCCNMGNGTNGCNTCNGCNGGNAARCCNTCN--- ACNCARCCNGTNYTNGTNACNCARCARAAYGARMGNTCNYTNAARTAYGARGTNACNMGN CCNGTNTAYAARMGNCCNATG------TCNTCNAARCARMGNMGNGGNTCNGAYGGNTAY CCNTCNACNYTNCARMGNTCNAAYAGYCAYACNATHATGACNGCNCARACNGAYGCNTTY AARGCNGCNAGY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TTYYTNGCN CARCARTTYGCNTCNGGNGARGGNAARTAYYTNCARGARAARYTNCARGGNAARGCNGAR AAYAARMGNAAYTGGYTNGCNAARTGGTGGGARGAYATHGCNTAYYTNGGNATGMGNYTN CCNGCNCCNYTNATGAAYATGGGNGGNCCNGCNCCNTAYGGNGARGAYATHTGGCCNGCN CARCAYGGNACNCARATHGCNMGNGCNGCNYTNYTNYTNCAYTAYAAYGTNAARTTYTGG CARTTYATHCAYMGNGARCARGTNAARCCNATGAARGAYGGNMGNGGNMGNCCNATHTGY ATGTTYCARTTYMGNMGNACNTTYAAYACNTGYMGNATHCCNGGNGTNCAYMGNGAYAAR YTNGARGARTAYTTYAARACNGARTCNGARGGNGARTGYCCNTCNCAYGTNATHGTNATG AAYAARGGNCAYATHTTYGTNGTNAAYACNYTNGAYGARAAYGGNGARGTNYTNACNCCN CCNGARTTYGARGTNCARTTYCARCAYATHYTNGARCARGCNAARAARYTNGGNCCNAGY CARGCNGTNACNTAYYTNACNACNYTNCCNMGNATHTCNTGGGCNMGNGCNMGNAGYGCN YTNATHGCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GCNAARTGYTCNGAYGGNCARATGTAY AARTGYGTNGTNAARTAYTTYGAYGARCARTAYAARYTNCARGAYGCNGTNGTNGARGAR AAYATGACNGCNATGGCNGGNGCNAAYYTNGTNGAYATGATHCCNGAYCCNGAYAAYTCN GAYTAYTCNGAYAAYGARACNYTNACNATGAARTGYACNGCNAARGGNCCNGARGAYTAY GCNTTYCARTGGMGNMGNAARTGYCCNTCNAARTTYAAYGTNCARCCNTAYTTYGTNGTN TGGCCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNGCNCARGCNGGNGCNMGNTCNTAYCCNTAYGGN ACNATGGCNGCNTAYCCNCCNGGNTAYCCNGTNCCNACNGCNGGNACNGCNCCNGGNCCN TAYCAYACN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYGTNATHGGNGARCAYGTNTAYGTNAARYTNCAYTGYCCNTTYAAR MGNYTNTGYGTNGARGCNGARMGNGTNAARATHGARATGCCNYTNAARGAYTGYGARATH ACNGAYMGNCCNGCNACNAAYTGYTTYCARMGNTTYGCNGAYAARTAYYTNGARACNGAR AAYGAYGTNACNGAYTTYGTNAGYACNCARTTYATHATGGAYMGNATHCAYYTNTAYGAR GGNTAYGARGAYCCNACNAAYTTYTTYMGNCCNGCNYTNMGNTCNYTNYTNYTNCAYCAY ATHYTNATHAAYYTNGAYATHMGNACNGCNAARGARATHGAYGCNGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GGNATHGCNYTNAARTAYGGNGTNCCN GTNCARGAYYTNAARMGNGAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGYTNTCNMGNTCNGGNMGNGCNGARACNMGNAGYMGNGCNAARGAR GAYATHAARMGNGTNATHAAYGCNATHGAYAARGTNMGNAARTGGGARAARAARTGGGTN ACNYTNGGNGAYACNTCNGTNACNATHYTNAARTGGGTNCCNGTNACNGCNCARGARAAY CCNGGNGCNYTNMGNAARATHCCNGGNGTNAARACNAARACNTAYTCNAARGCNMGNGTN GARMGNGARMGNGARYTNTTYGCNGCNGARACNAAYGGNCAYYTNMGNGCNACNTCNCCN TCNAAYAGY---------AAYACNAAYGCNTCNAAYACNAGYTCNCCNTCNTCNMGNAGY CAYCARGCNAAYGGNAARTGYCAYAARAAYGGNGCNGTNACNAAYAGYAAYGGNAGYGTN GTNTAYACNGARGARAAYACNCARCARTCNATHGGNTCNTAYGGNTCNGARAAYYTNAAY GARGAYTCNAAYATGTCNTTYCCNGARCAYAGYGAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGTTYGARAARCAYAAYTTYGGNGTNGCNCCNGTNACNTGYCAYGCNTTYAAYAARGAY MGNACNGGNYTNGCNYTNTCNYTNAAYGAYTCNAAYGTNAARATHTAYAARAARTCNGGN CCNAARTGGCARGARACNGAYACNYTNAGYGARCAYGGNCARMGNGTNACNAGYATHGAY TGGGCNCCNGTNAGYAAYMGNATHGTNACNTGYTCNGCNGAYMGNAAYGCNTTYGTNTGG ATGYTNGARGAYGGNAARTGGAARCARGTNYTNGTNATHCCNMGNATHAAYMGNGCNGCN ACNTGYGTNAARTGGTCNCCNAAYGARAAYAARTTYGCNGTNGGNAGYGGNTCNMGNYTN ATHGCNATHTGYTAYTAYGAYGAYGARAAYAAYTGGTGGGTNAGYMGNCAYATHAARAAR CCNATHMGNTCNACNGTNACNTGYYTNGAYTGGCAYCCNAAYAAYGTNYTNYTNGCNGCN GGNTCNGCNGAYTTYAARTGYMGNGTNTTYTCNGGNTAYCARAARGARGTNGAYGARAAR CCNGGNCCNTGYTCNTGGGGNACNAARATGCCNTTYGGNGCNYTNATGGCNGARTTYAGY AAYGGNGGNGGNGGNTGGGTNCAYTCNGTNTCNTTYTCNCCNAGYGGNGAYCARGTNGCN TGGGTNGGNCAYGAYTCNAGYATHTCNATHGTNGAYGCNAAYAARGGNAAYGARYTNGTN GTNGTNAARGARAGYTTYYTNCCNTTYATGAGYGTNAGYTGGATHACNGAYAAYTCNYTN GTNGCNGCNGGNTAYGAYTGYAAYCCNATGYTNTTYTCNTTYGCNGGNGGNAAYATHACN YTNAARGCNAARYTNGAYGTNCCNCARGARAARGARTCNGGNACN---AGYGCNATGAAY MGNTTYAARAAYYTNGAYAARAARGCNACNGCNAAYGAYACNTCNACNGAYYTNAARACN CARCAYCARAAYACNGTNACNCARGTNTCNATH--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNCARTTYCARTCNGTNMGNGCN ACNACNGGNTAYTAYGTNGAYACNACNTGYGAYYTNYTNGGNGGNGCNTTYYTNTGYTTY GGNGTNYTNTTYTAYYTNTGGAARMGNTTYGAYCCNTTYAARCARGAR------YTNCCN TCNTGGACNAARGCNCARGARGCNGGNGGNAARACNTCNYTNCCNGCNAAYGGNCAYATH TCNCAYAGYMGNGARACNTAYTCNAARAARTAYYTNTTYTGGAARGTNYTNTGYTAYGGN YTNTGYYTNGCNTGYGCNGGNAARTTYTGGGAYYTNGTNGTNGGNGAYTTYAARGAYATH TTYCARGTNGARYTNAARGAYCCNAARATGTCNGTNYTNCARTTYGAYGCNTGYCAYTCN ACNACNACNATHTTYATHTTYTAYATGTGGMGNGTNYTNGARGGNCARGCNYTNYTNCAR TAYTTYYTNATHCCNATHGTNYTNNNNNNNNNNNNNGARTTYNNNAAYTTY--------- ------------------------------------------------------------ ------------------CCNMGNYTNATHGTNTTYGAYYTNGAYTAYACNYTNTGGCCN TTYTGGGTNGAYACNCAYGTNGAYCCNCCNTTYACNATGGCNTCNAAYGGNAARGTNTAY GAYTCNMGNAARCARCAYGTNCARTAYTAYACNGAYGTNCCNGAYATHYTNAARCARYTN CAYAGYGARGGNATHAARYTNGGNATHGCNTCNMGNACNAGYGCNGTNCAYGARGCNTCN CARYTNACNGGNYTNTTYAAYTGGGAYCARTTYTTYCAYTAYMGNCARATHTAYCCNGGN TGYAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TCNGAYAAYGARAGYGAYYTNGCNCCN AGYACNACNACNACNCCNGARMGNAGYAARAGYAARGCNYTNTGGGAYTTYGGNCCNTTY ------------GCNAAYMGNATHCARAAYGGNACNTCNTCNCARMGNTAYTCNCAYCCN AARGTNTCNTGYAAYTCNGAYGGNGAYGARACNMGNACNTCNGAYAGYGGNAGYAARTCN GAYGAYAAY---------------------GCNGARATGCCNGCNACNYTNTCNTCNTCN YTNCARTAYTTYAAYTCNTCNCAYAAYGTNGAYCARGTNYTNTCNTCNTTYMGNGAYCAR MGNATHCARYTNGARTCNMGNTAYCARCARYTNAAYAAYCARGGNYTNGCNGARAARGTN TTYMGNATHYTNACNAAYCARGAYCCNGARATGCARGCNAAYGGNATHYTNTCNGARGTN AGYGCNGARGARMGNGARACNAARGCNMGNATGGTNYTNCARCARTAYAAYAARGAYTTY AAYTTYTCNTTYACNTCNAGYGGNMGNGARGARTCN---CCNAGYTTYGGNCAYCCNGAY AAYATHMGNAARAARYTNGAYYTNTCNGCNATHAGYTCNGTNGAYTCNAGYMGNGTNTTY GAYAARTCNCCNTCNAARGGNTTYTCNGCNTTYGAYGARGCNAARAARTTYYTNTCNACN CARACNGARAARGCNYTNGARMGNACNTTYAAYCAYAGYATHGARCCNAARGARAARTAY MGNCCNTAYMGNCCNCCNGGNTCNAARGARGTNTAYTAYACNGARAGYGAYACNGCNTCN GTNGCNGAYAGYGTNACNACNATHGARAGYACNCAYATHGGNTCNGAYGAYGCNGCNGGN CCNAAYYTNCCNCCNAGYGCNYTNGGNTCNMGNAARGAYCCNCCNAAYGTNGCNGGNATH TAYGGNACNMGNAARYTNTCNACNGTNCARGARGGNTCNGARYTNCCNACNATHGARGAR AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARACNAAYCCNGAYATG TGYAAYTTYYTNGARCAYTTYGARTGYYTNYTNGARAARGARAARATGATGGGNCARYTN AGYYTNYTNAAYATGGCNTGYGCNGCNAARGCNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGMGNATHTAY AARGAYATHTTYACNGGNGAYGARATGTTYAGYGAYACNTAYAARATHAARGTNGTNGAY GAYYTNTAYGARGTNTAYGGNAARTAYATHACN---MGN---AARCARGGN---GARGTN TTYYTNGAYGGNGCNAAYCCNTCNCARGARGAYGCNGAYGAR---GGNACNGAYGARGCN GTNGARTCNGGNGTNGAYATHGTNYTNAAYCARMGNYTNATGGARATGCCNTTYTCNACN AARAARTCNTAYYTNYTNTAYYTNAARGARTAYATGGCNAARATHACNGARAARYTNAAY GARACNAAYCCNGAY---GARGTNAAYACNTTYAARACNAARATGAAYGARACNGTNAAR AARYTNYTNTCNMGNTTYGAYGARTTYCARTTYTAYACNGGNGARAGYGCNGAYCCNGAY MGNGGNATGGTNYTNYTNGARTAY------MGNCARGTNGAYGGNGAR------GARGTN CCNATHATGATHTTYTAYAARCAYGGNYTNYTNGARGARAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATHGARAARTCNGARMGNAAY TAYCARATHGAYTGYGARAAYGCNCARAARGARTTYGAR--------------------- ------------------------GARAARAARATHGAYYTNMGNGARAAYYTNATHAAY GAYYTNAARGARAARMGNAAYATGATHGARYTNGARMGNCARACNATHGAYYTNAAYGGN GCNGAYTTYATGGARGTNAARCCNACNATGACNMGNAARYTNMGNMGNMGNCCNAAYGAY CCNATHCCNATHCCNGARAARMGNMGNAARCCNTCNCCNGCNCARGTNAAYYTNYTNYTN GAYGAYGAYCARATHATGACNGAYYTNMGNGTNATGATGAARGTNAGYGGNAARCCNGTN ACNAARAARCARGGNYTNAGYAGYCARAGYCCNYTNYTNGAYGGNCCNTCNGAYGTNMGN ATHGARGAYGGNMGNYTNTGGTAYGAYAARAARTGGTTYCARMGNAAYACNATGGTNCAR ATHGAYAAYMGNGARGGNGGNTCNMGNATHTAYGGNACNATHACNAAYATHGGNATHCAR GARATHTGGATHAARMGNAGYGGNGAYAAYTCNAARYTNMGNATHTAYATHTCNCARTTY CARAARGGNAARTAYATHMGNAARAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------ACNYTNTGYAARGAYTGGGAYATHAARCARTAYCAYAARACNGAYCCN ACNTTYTCNCAYAARYTNYTNATGGCNMGNAARCARYTNTCNGGNGTNGTNCCNTCNATH CAYAAYYTNMGNYTNMGNGCNGCNGTNACNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AAYATG CCNGCNTCNTGYACNAGYATHYTNAARGTNCARACNGGNMGNCCNCCNGGNAAYAARGAY GTNGTNTAYGAYGAYTTYGGNAAYGTNATHGCNGTNATGAARYTNGAYCCNGARAARYTN CCNTCNCAYAARATHAAYGTNAARTAYCAYGTNGTNGAYCCNGCNGTNGARGCNTCNCAR GCNMGNYTNGAYGCNATGMGNAARGGNAARTCNACNGGNAGYAARGTNMGNAARATHMGN TCNAAYAARAGYYTNTCNAAYGAYTCNGTNAGYACNGGNTCNAARACNAARACNGCNTCN ACNGTNGGNGCNGTNGCNCCNYTNCCNCCNCCNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGCNAARATHTGYGTNATHGGNGCNGGNGCNYTNGGNYTNTCNTCNGCNYTNAAYATH CARMGNACNYTNCCNCAYGCNACNGTNACNYTNATHGCNGAYAARTTYGTNYTNGAYACN YTNAGYAGYGGNGCNGGNGGNYTNTTYMGNCCNAAYYTNAAYGARATGGAYCAYGGN--- GAYAARACNGCNATHGGNAARTGGATHMGNGAYTCNTGGAAYTTYTAYGARAGYYTNGCN AAYTCNCCNYTNGCNTCNGARACNGGNATGATHTTYGTNTCNGGNATHGTNGGNCAYAAR ACNTGYCARGAYTAYGGNTAYGGNACNYTNAARAAYGTNGCNTAYGAYTTY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGATGGAYGARGTNCCN GTNCCNACNGGNTCNCCNCCNYTNCCNMGNMGNGGNGCNTAYTCNATHGAYTTYGAYGCN ATHGAYGARAAYACNAAYCCNTTYGCNACNAARAGYAARATGAAYYTNGGNTCNTCNCCN CCNATHAAR------TCNAAYTCN------------GGNTCNAAYGARGARGARAAYCCN TTYCARTCNAARATHAARYTNGGNAAYTCNCCNCCNGGNTCNCCNAARATHGCNTCNGCN AGYAAR------AAYGAYTTYTCNAAYGAYAAYTCNACNCCNAAYTCNGCNCCNCARGAY GTNCCNTCNAAYGCNGTN---YTNGCNGAYGAYAAYGCNGTNGARGGNAARCCNAAYACN CARACNACNCCNAARAARAARAARATGATHAARAARCCNAARGCNYTNTCNAARTTYAAR CCNCCNAARAAYTTYGGNGGNATGCARGAYTCNGARGARATHCARATHYTNATGCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGGMGNTTY GTNAAYYTNGGNATGGCNGTNTTYTTYYTNYTNGCNGCNYTNGCNAAYGTNAAYGAYGGN GAYTGGTAYATHTGGYTNCCNATGTAYYTNYTNCCNTCNGGNYTNTCNTCNATHGCNTGY ATHAARCCNGAYAGYGTNTAYAAYACNYTNTGGCARGGNATHACNACNATHYTNTTYGGN ATHACNATHYTNATGGGNGTNTTYCARATHTCNGCNYTNTCNGGNYTNGARAAYGARACN ---AAYAAYCCNYTNGTNYTNGARGARGGNMGNGARYTNGGNGGNYTNTTYATHATHYTN ACNTGGGCNGGNATHGCNMGNTTYTCNCCNTTYGGNAGY------CCNGCNTAYAARCAR GGNTAYTTYAGYATHYTNTTYTGYGTNGCNGCNACNATGGCNGTNGTNCCNYTNYTNYTN TGGTCNYTNTGYTTYGTNGGNGAYTGGCARCARCAYTAYGGNCAYTGYACNGGNATGTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNTAYATHATGCAYGARCARGARYTNAAY GGNATHYTNGCNGAYGARATGGGNYTNGGNAARACNATHCARGCNATHTCNTTYYTNGCN MGNYTNYTNGARGARGGNGAYGGNGGNCCNCAYGTNATHATHGTNCCNTCNTCNACNATH GARAAYTGGYTNMGNGARYTNCARYTNTGGTGYCCNGCNYTNAARGTNATHGTNTAYTAY GGNTCNCARGARGARMGNMGNACNGTNMGNCAYTCNGTNTTYTTYGARMGNGARGAYTTY CAYGTNYTNYTNACNACNTAYAAYATGGCNACNGGNGGNGTNGGNGAYMGNGTNYTNTTY AARAARTAYGARTTYCAYTAYGCNATHTTYGAYGARGGNCAYATGYTNAARAAYATGTCN TCNYTNMGNTTYCARAAYYTNATGAARATHTCNGCNGARMGNMGNYTNYTNYTNACNGGN ACNCCNYTNCARAAYAAYYTNYTNGARYTNATGTCNYTNYTNTGYTTYGTNATGCCNGAR ATHTTYCARGGNAARACNGARCCNYTNAARAARATGTTYGCNATGATHTCNMGNTCNGAY GAYAARAARAARAGYMGNTTYGARMGNGAYMGNATHGTNCARGCNAARMGNATHATGAAR CCNTTYATHYTNMGNMGNYTNAARAARGAYGTNYTNCARCARYTNCCNCARAARACNGAR AARATHATGAARTGYATHATGACNCCNTCNCARCARGARYTNTAYGAYAGYYTNYTNAAY MGNTAYGTNCARGAYGCNTGYGARGGNGARGARGARGGNGGNGGNGGNGGNATHGGNATH TTYATGCARTTYMGNAARGCNGCNAAYCAYCCNYTNYTNYTNMGNCAYYTNTAYGAYGAR GAYACNYTNAARAARATGGCNAARAARATHTCNACNGARCCNTCNCAYMGNGARMGNGGN GCNYTNCCNAARYTNATHYTNGARGAYATGTCNGTNATGAAYGAYTTYGARYTNATHGGN YTNTGYAARCARCAYAARAARTAYYTNAARAARTTYGARYTNGAYCCNTCNGTNATHGGN GAYTCNAGYAARTTYAARAARYTNGAYAARYTNYTNCCNGAYATGAARAARATGGAYGAY MGNGTNYTNYTNTTYAGYCARTTYACNATGATGYTNGAYATHGTNGARYTNTAYYTNGAR AGYAARGGNTAYAARTAYATHMGNATGGAYGGNCARACNCCNGTNCCNGAYMGNYTNCAR YTNATHGAYMGNTTYAAYAAYGARCCNGAYATHTTYATHTTYYTNYTNTCNACNMGNGCN GGNGGNYTNGGNATHAAYYTNACNGCNGCNAAYGTNATHATHYTNCAYGAYATHGAYTTY AAYCCNTAYAAYGAYAARCARGCNGARGAYMGNTGYCAYMGNYTNGGNCARAARMGNGAR GTNMGNGTNGTNAARYTNATHTGYGARGAYACNGTNGAYGARGCNATGYTNMGNTGYGCN AAYGAYAARYTNGCNYTNGARAARGAYYTNACNGGNACNCAYGARGARGARAAYGARGAY MGNAGYAARGAYGTNGGNAAYATGYTNAARGARATHYTNAARYTNTCNCARAARMGNMGN ---------------GGNATHYTNACNGTNGARTCNCCNYTNAARTGYAGYTGYCARGAY YTNYTNTCNATGTCNAGYGTNGTNAARTGYGGNTGGYTNMGNAARAARAGYYTNATHAAY ATGTTYCARYTNAARYTNTTYAAYTGGCCNCARGTNTAYGTNGTNGTNACNGGNAARTGY YTNTAYTAYTAYAARAAYGARACNTCNAARAARTCNTCNGGNAGYGTNTCNYTNTAYGGN TTYTGYMGNATHACNMGNGCNCAYGARATHAARTCNAGYGARGCNGTNTGGGCNTTYAAR ATHGARCAYATHCARCCNAARATHCAYTCNYTNACNTTYTCNGCNTCNTCNGARAARGAY ATGATHMGNTGGATGAARYTNATHAARCARGARATGYTNATHGCNAAYAAYAARGARGCN MGNAAYTCNCARAAYTAYGTNTAYAAYGGN---TCNGCNGARTCNGAYGARTCNATHACN TCNTCNGAYTAYAGYGCNYTNGARAGYAGYGTNTAYGAYYTNGCNGTNAGYGGNMGNCCN ACNTCNTAYATG---GAYTTYAGYTTYYTNACNACNGARGARAARGAYTGYACNCCNGCN GARGCNTGYAAYCCNAAYAGYTTYYTNCCNCARCCNTTYTTY------TCNAGYGAYGGN GCNGCNTGYCCNAAYATHGAYTAYTGYYTNCARAARGAYATHCCNCAYGARAARACNTAY AGYGCNGARGAYGAYTAYTGGGCNTCNATHCAYTAYGAYGGNACNAARGTNCARAGYGCN AARATHATHAAYAAYYTNGGNGARAAYGGNGTNTAYATGGTNMGNAARAGYAAYGAYGGN ATGAAYGTNYTNGTNGTNTTYTCNGAYGGNGTNAARAARTAYAARATHYTNGARAARGAR AAYGGNGAYTTYGCNYTNTCNAGYGGNGGNCCNTTYTTYAARTCNYTNGARCARYTNYTN TAYCAYTAYTAYAGYGAYGCNYTNCCNGGNTGYAAYCARAARYTNTTYATGCCNTAYAAR YTNCAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARCARAGYYTNGGNMGNGAYGGNACNATGCARGTNACNGCNAARGARGGNATHGAYTAY YTNAARTCNGARGGNMGNACNACNYTNYTNAARCAYCARGGNYTNYTNAARGAY------ ------------------------------------------------------------ ------------------------------------------------AARCARGCNYTN YTNMGNGAYGGNACNATGGTNGCNACNACNAARGARGCNGAYMGNYTNTTYGARGGNAAY AARCCNGAYGCNGAYGCNCARACNMGNGGNCARCARAARCARATHGAYGAYATG---AAR ACN---ACNGARCCNCCNTCNAARAARAGYAARATGGCNAARGAYGGNACNATGGCNGTN ACNGCNAARGARGCNAARACNATHYTNGCNGGNGARAARYTNGGNGAYACNMGNCARGAY ACNACN---GCNAARAAYAARGCNAARATHCCNYTNAARAARAAYACNACNATGGCNAAR ACNGTNGARGARGCNAARTAYGTNYTNGAYGGNAAYGTNAAYGTNAAYGARGGNMGNAAR ACNMGNTCNCARAGYMGNGGNGAYCCNCCNAARCCNGCNATGAARMGNGCNGGNACNATG CARAAYACNGCNAARGARGGNAARGTNTAYYTNAAYMGNGGN------------AARGGN AARAARGCNGCNGTNGCNCCNGTNGARGARYTNGAYGARGCNGCNMGNATGMGNCAYAGY TCNAGYTCNCCNGTNYTNGGNAGYCARTCNGCNTCNAGYAARTCNGCNGGNGCNYTNAGY MGNTCNACNGAR---------------------------------------GAYAGYAAY YTNACNTCNTCNMGNYTNAGYGCNYTNMGNAARAAYGGNTTYGGNGCNGCN------GGN TCNAGYMGN---ATGTTYGAYTCNGGNACNTTYACNMGNCCNAARMGNGCNTCNAAYTGY GCNCCNTCN---CAYGGNGARGGNGAYCARCARCAYAAYGTNCCNAAYGCNGARGAYATH GARAAYYTNGCNAARCARCARGARGARAGYYTNMGNCARAGYGTNACNCCNGTNAARAGY ACNATGMGNGCNAARCAYTCNYTNATHGARGGNGAYAAYGGNGCNMGNGTNAGYCCNAGY MGNTTYGAYGTNGAYGGNGCNTAYYTNAAYCARCAYMGNGGNAGYTTYAGYTCNGARCAY AGYACNCCNCCNGAYAGYCCNCAYGGNAAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATHGARCAYGGNGARYTNCCNYTNAARTAYMGNMGNAARGCNATH TCNAGYGARGARATHGARTTYATHGARAARGGNGGN------------------------ ---------------------------------GAYAARMGNCARYTNTTYGGNATHTGY GTNGARGARTGYAGYYTNATGYTNCARAGYYTNGGNACNGARCARTGYCCNACNGGNCAR GTNTGYGCNTCNAAYGGNTGYGGNCAYACNTGYCARTCNGAYACNTCNGCN--------- ------AAYAARTGYTCNGGNGTNATGTGYGCNATGTAYTGYMGNAAYGGNTTYCARACN GGNGAYGAYGGNTGYCCNATHTGYAARTGYGCNCAYTCNGARGTNGTNACNGAYGAYGAR GAYGGNYTNCARCAYTAYGGNCARGGNGCNGGNGAYYTNAARAARAARMGNGGNYTNMGN MGNYTNTTYGGNMGNYTNAARMGNAGYAGYTCNCARGAYYTNGARGGNGGNMGNGARAAY MGNYTNGGNGARGGNGARTTYMGNMGNGGNGGNGTNMGNGCNACNGCNTCNGCNMGNYTN GCNTGGAAYMGNGAYGTNAARGGNMGNATGGCNAAYACNGAYATHCCNTTYGCNMGNTGG GAYGCNGARMGNATHACNGCNTGGATGAAYGAYATHGGNYTNAAYATGTAYYTNGTNGAY TGYAARMGNTGGGTNMGNAAYGGNGARCARYTNYTNMGNTGYTCNYTNCAYGAYYTNGAR AARGARYTNGGNATGAARAAYTCNYTNCAYMGNAARAARYTNCAYYTNGCNATGCARGCN GTNACNTCNAGYYTNCCNAAYCAYYTNGARGARYTNGAYCAYAAYTTYGTNACNMGNTGG YTNGAYGAYATHGGNYTNCCNCARTAYAARGAYGCNTTYTAYGARGCNMGNGTNGAYGCN MGNGTNYTNAAYTTYYTNACNYTNGAYGAYYTNTTYCAYYTNAARGTNTCNAGYGARGTN CAYCAYGTNTCNATHAARMGNGGNATHCARGTNYTNMGNYTNAAYAAYTTYAAYCCNAAY TGYYTNMGNMGNMGNCCNGCNTCNGAYGARCARAARTTYACNAARGGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYCAYACNCARGCNTGYCCNYTNYTNTTY CARGCNACNCARCARYTNTGGGCNGARCCNATGAARAARAARAARMGNYTNGAYCCNGGN GTNATGYTNGCNMGNACNCARAARAARYTNAARAARATHGAYAARGARATHAARMGNYTN ACNMGNTTYGGNAARATHYTNAARCCNGTNGARGARATHGARGTNGAYMGNMGNAARYTN ACNGCNTCNGGNGARMGNAARMGNGARCCNATHGTNYTNACNTTYGARGARAGYGARTCN MGNGCNYTNYTNCAYAARMGNTGGGCNMGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNAAYAARCAYTTYCAR ATGATHGCNATHCAYGAYNNNTTYNNNNNNTCNNNNAARAARGTNACNTCNGARGAYGTN TGGAARCAYYTNTCNACNYTNTAYGAYYTNCARGCNYTNAAYGARTCNGARATHGTNCCN TTYCCNAAYAARAAYGGNGAYTTYGTNYTNACNGAYAARGAYATHGTNGAYYTNTGYAAY MGNAGYTTYCCNMGNTCNTCNTTYATHACN---------CCNGAYATGGGNAARCCNGAR ---GGNAAYGTNAARAARGARTCNAARCCNGCNAARATGGARCCNAARATGGTNTTYCAR ACNCCNAARATHGARGTNAARCARGAYTCNAAR---CCNTCNAGYTCNAGYAARTCNGAY AGYMGNTCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGCARGARCARTAYTGYGGNACN YTNTCNTAYATGGCNCCNGARATGAAYTCNACNTAYTCNCAYYTNGTNGAYGTNTGGGCN ATGGGNYTNATHATGTAYTAYYTNYTNACNAGYTAYCCNAARGAYAAYGTNYTNAAYGAR TCNYTNGCNGCNGAYGGNCCNAARTTYACNGARCCNGARYTNGARTCNGTNAGYTCNCAR GCNAARGAYYTNYTNAARGARATHYTNACNCCNGAYCCNGCNTAYMGNCCNTCNTCNGGN GARGTNYTNAAYCAYGARTGGTTYACNGGNAARAARMGNGARTAYGGNAAYGTNYTNCAR ATGATGAARGARTTYGGNCARGARCARAARGARGGNGCNAAYGARMGNGARGGNGAYAAR GGNGTNAAYAGYGCNATHAAYGGNYTNGGNCAYYTNGARACNAGYGGNAGYGCNGCNCCN TCNAAYACNTCNTCNGGNAAYAARGTNTCNGCNGGNGAYGGNAARGGNCAYACNCCNCCN GGNTCNGGNAGYAGYAARACNATHTCNCAYAGYAARACNCCNACNYTNGAYAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNAARCARCARTTYCARATHYTNCARGAYCARCAR CARCARAARYTNYTNGARMGNMGNAARAARAARGARGARCARAARAARAARAARGAYAAR AARACNGARGARAARGCNYTNGGNAARTTYGGNGTNTCNGAYGAYYTNGGNYTNAARYTN GCNGAYCAYTCNAGYGGNAGYTTYGGNTAYGTNTCNGARGARYTNGTNGAYCAYYTNAAY GARCARATHMGNCARATGAARGAYGARAAYGGNMGNYTNTAYAARYTNYTNAGYGARAAR GAYTTYGARATHMGNCARYTNAARAARAARAARGARGAYCAYATGATHAGYGCNATHGAY ACNTCNGTNACNAGYGARACNGCNGCNACNAARATHATHGARYTNAGYAARAARGTNMGN GARYTNACNTCNGARAARGARGCNGARAARACNMGNTGYAARCARTTYCARAARAARTGY CAYGAYTTYCARGTNCARYTNCARTCNCARCCNGTNCARTCNGAR---GAYTCNGTNATG GGNTCNGTNGTNAGYYTNMGNTCNGCNYTNGAYAAYAARGAYGAYGAYGCNGTNGAYGTN AARGCNYTNCARGAYMGNYTNAARCARTCNGARTCNMGNYTNACNGAYTAYMGNAAYCAR TGYCARCARYTNMGNCARGARYTNAARGTNGCNCAYAARGTNYTNAGYCARGARATHGGN GARAAYGTNAAYATHGCNGCNYTNYTNAAYGARACNAGYCARTGGMGNGGNMGNGCNCAR CARGTNATHGCNYTNCARCARAARGTNGAYGARYTNMGNGCNMGNTAYGARGCNAGY--- ATGGAYATGAGYAGYGGNACNGGN---------TCNACNGCNMGNAARMGNCARGARGAR AARTAYMGNGARGARYTNMGNMGNGTNGAYAARGARMGNAARGARGCNCARGARATGACN GTNAAYAARYTNAARGGNYTNGARGARGARAAYGGNCARYTNAARAAYAARYTNGAYGCN TCNAARTCNMGNAAYAARGTNATHTCNTAYGAYYTNAARGGNATGAARGCNCARGTNCAR ACNYTNYTNAARAARAGYCARAAYGAYGAYGARTTYATHGAYGCNYTNATGAARCARCAR AARCARATGAARGARATGATGGAYCARACNGTNATGAARCARACNCARCARGARYTNCAY CARCAYCARCARYTNCARCARATGAAYATGAARAGYCARCARGAYAGYAAYGTNGTNGAR CARYTNAARYTNATHGCNGCNCARAARGARGCNCARGTNAARATGYTNGARATGGARYTN GARCAYYTNMGNAGYTCNCAYTTYCARAAYCARAAYMGNCARTCNGARACNCCNATHTCN TCNCARCCNTCNTCNGCNATGTCNMGNTCNTCNGTNACNCCNGTNGCNGAYCAYCCNTGY GAYGTNACNACNAAYMGNCAYMGNGARTCNAGYCARGTNATHYTNTCNAGYGCNMGNAGY ATHTCNMGNTCNTCNAGYMGNGCN---------GTNGGNCAYCARYTNAGYAGYCCNGAY AAYAGYAGYAGYMGNAARGARATGTCNGTNYTN---------MGNTAYCARYTNCARGAR YTNTCNGTNYTNTCNAARGCNGTNGARGTNGARMGNGAYAARATGACNGARYTNGTNCAR GTNYTNCARTCNMGNYTNAGYGARGARGTNGGNAARCAYTCNGCNACNCARCARGAYYTN CARAGYCARAARMGNACNGTNATHGARYTNGARAARAARYTNGGNMGNAARACNATHGAR GTNATHAARMGN---CAYGTNAARGGNATGACNTCNTCNMGNGAYGAYGGNGAYGAYATH YTNGAYGAYGARGTNGTNAAYACNAARGCNGARYTNATGACNMGNYTNGARATHCARAAR GAYGARAAYGARTCNYTNAARATGACNYTNCARMGNAGYYTNAARGCNAARGARGARGAY YTNAARGTNTAYAGYAARACNYTNGARGARACNAARCARGTNTTYYTNCARGCNYTNMGN CARATGAARGAR------------------------------------------------ ------MGNAARACNYTNYTNGGNYTNGARAARGARYTNGTNGAYTTYGTNGCNGAYGGN TCNYTNCARTCNCAYAARYTNGCNGARATGAAYCCNTAYGAYMGNATGGTNGCNCAYMGN GTNGCNGCNTAYYTNGGNYTNGAYCAYAAYGTNGAYCARTCNGGNAARTGYATHATHGTN AGYMGNACNAGYYTNACNMGNATHCCNCCNACNMGNYTNATHGAYCCNTCNGARGARTCN GAY------AGYCARCCNAARMGNMGNATHYTNYTNAARAARCCNACNAGYYTNGAYGAR AARCARACNTGGAAYAGYTGYAARGCNCARTTYGGNTCNAAYMGNGCNAARTCNYTNGAR GARMGNCARCARATHTAYACNGARGTNMGNGARMGNATHTTYAARGCNGTNGARAGYACN CCNACNTCNTCNAAYTTYCAYTAYATHCCNCARCARGGNAGYYTNGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARTTYAAYCARTTYMGNYTNGAYAARTTYGARCARYTNCARCARGAYMGNTTYAAYAGY TTYAAYMGNYTNAAYAARAARCAYGARAARGARAARGCNGTNYTNYTNCAYTCNGCNGAY AARTCNCCN---AAYGCNGAYTTYATHAARYTNTAYCAYGAYYTNATGACNTCNCARCAR ATGCARAARGARGCNYTNTGYGGNGARYTNGAYCARMGNGARATGCARGARATHCAYAAY YTNAARCARGARGTNGAYAARAARGARTAYAARGCNATGGARCARAARACNGAYCARYTN TCNGARAARGTNGARGGNACNTCNAAYYTNACNTCNAARGARGCNGARAARYTNYTNAAR ATHCAYAARYTNCARATGGCNCARTAYAAYGCNAARCARCARAARGARAARCARGCNATG YTNACNMGNYTNCARGAYAARYTNCARCARMGNYTNGAYGARGCNGAYGARACNGARGCN MGNGAYCARAARGARCARGARAAYYTNAARGARCARCARATGGCNACNATGGAYAARGTN YTNGCNACNAAYYTNGAYYTNACNGARGARGCNAARGARCARGTNYTNMGNGARCAYGAR CARAAYYTNCARGCNYTNTCNAAYCARYTNATGMGNAGY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATHGAYGCNGGNAAYTAYCARGTNAARTGYATHGCNMGNGGNAGYAAYCCNGCN ACNAARGARATHCARYTNTAYYTNGAYGGNGARAARGTN---AAYAAYAARMGNCCNATH TTYAARMGNATGGARGAYTCNGTNMGNAARTAYCARTCNATHATHACNGCNACNGTNGAR GTNCAYGTNAARCAYTCNGGNAARGARYTNCARTGYGTNGCNAAR------GGNCCNAGY GGNATHCARYTNTCNACNAARYTNGARATHGAYGTNAAYATGTAYGAYCCNGARGTNCAY TGYAAYCAYAGYCAYGCNTAYATHGGNCARATGAAYCCNGTNTTYACNTGYATHGTNAAY CAYACNGAYATHCARGTNGARGGNTTYGCNTTYGARATHGGNTCNACNAARGARYTNATH MGNGARGGNAGYGCNGAYGAY------------AAYATGGTNGTNGTNAGYAARCCNYTN TCNTCNGGNATHACNGCNGTNACNYTNAGYYTNAARAARGCNGARAARTGGCAYTTYCAR AGYGAYTAYTAYYTNATH------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TTYYTNAGYATHACNYTNGAYTCNGAYATHATHAAR---AARTGGCAYGGNTTYGAY TTYMGNTCNAARCARYTNCARGCNYTNGCNGARGCNYTNTCNCCNTGYGAYYTNMGNYTN GGNGGNACNGARGCNGAYTTYYTNACNTTYGTNCCN---------------GAYGGNCAR TCNMGNTCNGAYGTN------CARGAYGAYTTYTCNMGNYTNGARGARTAYYTNTAYGAY GAYCAYGTNACNGGNMGNATGCAYAARTCNCAYAAYTAYACNATGACNGGNGCNCARTGG AARCARATGACNCARTTYTTYCARYTNGTNMGNTGGGAYYTNYTNTTYGAYTTYAAYYTN TTYAAR---GGNACNCCNTAYTGGGAYCCNACNAAYGCNAARYTNYTNYTNGAYTAYTCN ACNGCNMGNAGYGTNCCNATHCCNGCNTTYCARYTNGGNAAYGARCCNAAYTCNTTYCAY CAYAAYTTYAAYTTYTCNATHGARCCNTCNYTNYTNGTNAARGAYTTYCARATHYTNAAR CARGTNATHTCNMGNTAYCCNCARTAYAARGAYAGYAARYTNTAYGGNCCNGAYGTNACN AAYYTNAAYMGNCAYTCNTCNTCNMGNAARTAYYTNTGGCARTTYATGGCNTCNGGNGGN TAYAAYGTNGTNGAYGARATHTCNYTNCAYCAYTAYTAYYTNAAYGGNMGNACNGCNACN GCNGAYGAYTTYGTNAAYCCNAARGTNYTNGAYTCNYTNMGNATGGARYTNTCNATHGGN YTNAAYATHACNCARTCNCARCCNATHMGNYTNACNGARACNTCNTCNTGYTAYGGNGGN GGNGCNCCNGGNYTNTCNAAYAAYTAYGCNGCNGGNTTY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNGTNAARAGYAARCCNGARGGNGAYATHAGYGARYTNTTY GGNGCNGARGAYGTNGAYTAYMGNAAYYTNGGNAARGGNCCN---TCNYTNATGATHCCN CCNCCNATGCCNGCNGARACNYTNYTNTCNCCN------AARAGYCCNGCNCARMGNMGN TGGAGYCARTTYAARGARAARCAYCCNGAYGAYTTYGCNCARGAYATGGARMGNAARMGN YTNMGNGAYGCNCARATHCARGARATHCARGAYGTNGAYATGMGNCARGTNTCNGCNMGN CARMGNGCNYTNCCNYTNCCNCCNATHYTNGAYATHTCNGARGARGARCCNCCNGTNGTN MGNMGNGGNATGATHATGCARMGNGCNGAYAARGAYYTNAARGARGGNMGNYTNAGYCCN GGNGGNCAYMGNGARTTYYTNMGNCARGTNGGNGARGTNTAYGAYATGCCNMGNGCNGAY ATGACN---GGNCCNCCNAARTCNATHATGMGNGAYCCNMGNYTNMGNGGNAGYMGNGAY CAYMGNCCNCARGARAAYATHAARTCNTGYCAYACNCARGAYCARCAYATGMGNCCNYTN CCNAARTCNGCNMGNYTNGAYGARGGNGCNATGGCNTCNCCNGTNTAYCAYGAYGARMGN GGNGGNATGMGNTTYGARMGNMGNMGNAAYGAYAARTAYGAYMGNGGNGTNTAYCARMGN CCNCAYGARMGNMGNTTYCCNGAYACNACNGAYGARMGNGARGGNGARGCNCCNGAYTCN GAYATGMGNATGCCNTTYGAYGGNCCNAARGGN------GCNCCNAAYCCNCAYGARCCN CAYAAYACNACNAGYCARCCNCCN---YTNGARGGNCCNCCNMGNCCNYTNGGNCCNCCN ATHYTNCARGGN------------------------------------------------ ------------------------YTNGARACNAAYGGNCCNATHMGNGGNCCNGCNCCN YTNCCNCCNMGNCCNGGNCAYGCN------------------------------------ ---------------CCNNNNCCNNNNNNNNNNGGNNNNGCNCCNGAYCCNGGNACNTCN ATHATHGCNGAYCCNYTNGAYGAYCCNMGNTGGGGNCCNATGMGNGGNYTNYTNGAYTCN GAYGGNACNGARGARGTNGTNYTNGAYGAYAARCCNTTYGARYTNMGNATGGGNACNAAY MGNAAYYTNMGNATGTAYGGNCARGTNTTYGAYGTNGCNGTNGAYYTNAARGARMGNGGN ATHMGNGTNGAYGAYCARYTNGTNTAYAARYTNGGNGARCCNATHAARGARGTNCCNATH GGNGARMGNATGGTNMGNYTNTAYTAYCAYGGNYTNCCNAARCCNATHTGGYTNGAYGCN CARCARCAYGARATGMGNATGGAYGCNCCNCCNMGNAAYGTNATGGTNGAYGARGTNCAR MGNGGNTTYCARATHGAYGGNMGNGAYATGATGYTNYTNGTNGAYMGNYTNGARAARGGN CCNTAYGGNGGNCCNCCNMGNAARATHMGNATHYTNGGNAARGARCAYGARATHAGYTTY CARTTYCCNCCNMGNCARATHYTNATHGAYGAYAARCCNTGYGCNYTNAAYYTNGAYAGY AARATHCCNTAYGCNATHATHGAYGGNAARCCNCAYGGNATHMGNTTYGAYGGNGARCCN MGNACNATHTTYATHAAYGARCARCCNTAYATHGTNCCNYTNGAYMGNGCNGTNAARATH MGNATHGGNGCNMGNCCNACNTAYATHGCNTTYGGNGGNCCNGCNCAYGARGTNATHATH GAYGGNAARTGGTTYGARGTNAARTTYGAYAAYGTNCCNAARGAYATHCAYYTNGGNAAY MGNCAYTTYTCNATHMGNAGYCCNGGNCCNYTNCCNMGNGTNAARATHYTNAAYCARYTN CCNCCNAAYTTYGAYGTNTCNCARYTNATGGTNTCNCAYATHATGGGNCCNGARACNCCN ACNCARGCNGGNGTNAARAAYGTNACNMGNATGAAYCCNGCNGCNCCNGGN--------- ---------------------------CARTCNCARGGNCCNGCNGTNATHCCNCARCCN AAYYTNCCNCARCCNATGGTNCCNAAYMGNATGCCNGGNGTNGGNGTNATGCARCCNGGN CCNMGNGGNATGATGCARGGNAAYCARGGNATGATG------------CCNCARCARCAR CARCCNGAYGTNATGCARCAR---------------------GGNAAYCCNATGATGCAR CARCARGCNGGNCCNGGNATHATGCARCARGGNAAYCCNATGCARCARGGNAAYCCNAAY GTNATGCARCARGGNAAYYTNAAYATGATGATGCARCARCARAAYACNGCNATGATGGCN CARCARGGNYTNGGNATHYTNCCNAAYATGATGGGNCARGGNCCNACNATGATHCCNCAY CCNAAYCCNATGAAYMGNCCNGCNTCNGGNATGATGCARCARACNCAYAAYTTYATGCAR AGYATHATGMGNCCNCAYYTNCARGGNAAYACNATGYTNCARCARATHGGNYTNMGNGGN GCNATGTCNAAYATGATHGCN------ATGCARGGNAAYCCNCARCCNGTNAAYYTNATH GCNMGNGGNYTNYTNAAYCARGTNGCNAAYAGYATGYTNMGNCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MGNATHYTNTGG GCNGCNGARAAYTAYMGNYTNGAYGTNGTNMGNGARYTNYTNAAYTCNAAYCCNGARYTN GTNTCNTCNTGYGAYAGYGAYGGNTAYACNCCNYTNCAYMGNGCNTCNTAYAAYAAYCAY TGYGAYATGGCNAARYTNYTNATHTCNCAYAARGCNAAYATHGARGCNAARACNGGNGAY GGNTGGCARCCNYTNCAYAGYGCNGCNMGNTGGAAYTCNGTNGARACNGCNCARYTNYTN GTNAAYTGYGGNGCNGAYGCNAAYGCNCARACNAAYGGNGGNYTNACNCCNYTNCAYATG GCNTCNTCNGARCCNGAYGAYGGNMGNACNATHGARYTNYTNYTNAGYAGYCCNTTYATH GAYGTNACNGTNACNTCNAAYGCNGGNGARACNGCNMGNMGNGTNTGYGARMGNACNAGY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARCARYTNAARAARGCNMGNGAYGCNYTNAAYCARAGYGAR TAYGCNGTNGARGARYTNCARGCNCARYTNAARGCNGARMGNGGNGARTAYGARAGYAAR ATHMGNCARCARGCNYTNCARTTYMGNGAYAAYTCNGARGAYCAYAGYGARACNGTNAAR CARMGNATHCAYGAYYTNCARAARATGGTNGCNGAYCARAAYGTNGTNATHYTNGCNYTN GGNMGNGARAARGCNGARYTNGAYMGNACNGAYAARATGAARTCNGCNAGYCAYGCNAGY MGNGTNACNGTNAAYTGYTAYGTNAGYGGNATGMGNGGNGGNTAYYTNTAYCARYTNTCN CCNTCNATHAGYCARCAYYTNCAYGTNGTNACNAAYACNGGNGTNGARACNTAYACNTCN MGNTGGGCNGCNGTNGCNYTNGAYTTYYTNGCNYTNYTNTCNAARATGGARGAYCCNGAR AGYTCNGARGARACNGTNTGGAGYATGTAYATHATHCARTGYGCNAGYYTNGTNGAYCAR GTNAAYGAYATGYTNYTNTTYGCNGARAAYATHMGNGTNATGGGNCCNTCNTCNTAYGTN CAYATGYTNCARGARGCNCAYYTNTTYATHAGYTGYAAYYTNACNYTNTCNTTYCCNAAR GARGARGARYTNMGNGARTGYYTNCARCAYGTNTGYMGNYTNYTNGGNGAYTTYTAYGCN CARCCNGAYCARGARAAYTGGCARYTNTGYTCNCCNTAYTAYAARAGYATGGGNGGNTGY GTNGAYGGNYTNGTNACNMGNGCNGTNCARGARGCNGARCARTCNGGNTGYGCNGTNTTY GGNMGNGGNATHYTNCAYTTYYTNGARYTNYTNYTNTTYTCNGTNYTNTCNYTNGAYTCN YTNYTNATGYTNYTNAARAGYCAYGGNGARTCNGAYATHYTNAARAAYACNCAYATHAAR CARGTNYTNGARCAYGTNYTNACNGAYGARAARMGNTCNTTYYTNTTYGARAAYGCNGTN AGYYTNYTNAGYGARATHTAYGTNTCNCARATHAAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNAARYTN GCNYTNCARCAYTAYAARGCNAAYGTNTCNYTNACNYTNCARCCNYTNCARGAYAARYTN GARGCNYTNGAYAARGARCARMGNAAYACNACNTGGATGYTNGGNGAYGTNACNGARMGN YTNACNTCNGARATHGCNAAYGTNTCNYTNACNCCNGGNCCNCARGGNCARGCNGGNGTN GTNAAYATHTCNYTNTGYCARTTYATGTCNACNTCNAAYACNGCNCARTCNTCNYTNTCN TAYCCNACNAGYACNGGNTAYAARCCNGAYTCNTCNAAYATGGARAAYTAYTTYGTNYTN TTYGCNTAYTGYAAYTAYTCNGGNGCNACNGAYGCNAAYYTNGARGARAARAARGTNTCN TCNAARGTNTCNTAYMGNTGYCAYTGYTGGGGNYTNGAYAAYGARGAYAARACNGTNTGY ACNYTNAARTAYTGGATHTGYCCNMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TGYTGYYTNTCNGCNACN------------------------ ------------------------------------------------------------ ---------------------------------------------AAYYTNATHYTNGGN ATHTCNAAYACNACNCAYCAYATHCCNMGNAARGTNGAYTTYGARGAYGCNGTNMGNAGY GTNTCNTCNACNGTNYTNTTYGARTCNCAYMGNGGNAARYTNATHGCNTTYGTNACNTGY ACNGGN---TGYACNAAYGCNATHGGNYTNACNGGNGAYCARAARYTNATHATHTGGAAY GTNGAYAARGGNATHGCNYTNAARAGYATHCARATGCCNGCNGCNYTNCCNTGYYTNACN AAYGTNATGGCNGCNGARGCNATHAARGGNTTYYTNYTNYTNACNTCNTCNTGGMGNGTN GAYGAR---TCNGAYTGYGGNGGNYTNATHATHYTNAAYCCNYTNACNGGNCARGCNGTN AARGGNTGYGTNTAYAARATHCCNAAYTCNGGNTGGMGNMGNGTNGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TAYACNGCNTCNATHGGNGTNCARTCNCCNCCNAAYAGYACNTCNGGNYTN AGYTCNGTNCCNATHAAYAAYCCNAGYTCNTCNCCNMGNCCNAGYATHYTNMGNAARMGN ------------------------------------------------------------ ------------MGNACNGGNYTNGAYGTNGAYCAYAAYGGNTAYGTNAAYYTNGAYGAY GTNATHCARATHCAYYTNYTNTCNGARTAYTCNAARGAYGARGTNTTYGCNGARATHAAR ACNTCNATHTCNAGYMGNAAYACNGARMGNTAYCARTGGMGNGARAARGAYGGNAARATH TAYATHMGNGCNGCNTAYYTNMGNCARTTYGARAARAGYCCNACNCAYCCNGGNAGYCAR GTNTTYACNYTNTTYGARTGYTCNATGAAYTAYGTNATGAAYAAYYTNGAYTAYTAYGAY YTNGARGAYTTYCCNGAYGARCAYATHATHAARYTNATGGTNCAYMGNYTNAARMGNCAR AARMGNYTNAAYACNAARTGYYTNCARGCNYTNYTNGTNCCNACNATHACNMGNYTNGAY YTNCARGGNATHTTYYTNACNAAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GGNTGGACNGTNYTNCARAARMGNCAR GAYGGNAGYGTNGAYTTYTAYMGNGGNTGGGARGAYTAYMGNMGNGGNTTYGGNAGYYTN GARGGNGARTTYTGGYTNGGNAAYGAYAAYATHCAYTAYYTNACNTCNCARGARGAYACN ATGYTNMGNATHGARATGGARGAYTGGAAYGGNAARAARTAYTAYGCNGTNTAYAAYCAR TTYMGNATHGAYGGNYTNGARCAYAAYTAYMGNYTNCAYGTNAGYGGNTAYCAYGGNGAY GCNGGNAAYTCNYTNACNTCNYTNTGGGARAAYCAYGAYGGNATGCCNTTYAGYACNAAR GAYACNGAYAAYGAYGGNMGNTTYTAYGAYTCNTGYGCN--------------------- ---------------------------------------------------YTNGGNAGY AARATHAGYYTNATHTCNAARGCNGARATHMGNTAYGARGGNACNYTNTAYACNATHGAY CCNAAYGARGCNACNGTNGCNYTNGCNAARGTNMGNTCNTTYGGNACNGARGAYMGNCCN ACNGAYMGNCCNYTNCCNGCNMGNAAYGARGTNTTYGARTTYATHATHTTYMGNGGNCAY GAYATHAARGAYYTNCAYGTNTGYGARCCNCCNAARATHCARGCNACNGAR---GGNGTN CCNCCNGAYCCNGCNATHGTNAARTCNTCNCARCCNCCNCCNGGNCCNGGNGGNGCNGCN GCN---------TTYCAYGGNGCNCARCAYTTYCAYGGNCAYTCNTAYCARACNTTYGCN CARCCNATGTAYTAY---GGNCARGGNCARCCNGCNCCNGGNTTYGCN---CCNCCNCAY CAYGGNCARCCNGGNTCNCCNMGNGARGARTCNCCNMGNYTNGARCARTCNCCNGARCAR ATHAGYMGNCCNCCNATHTCNGCNATHGGNACNMGNCCNGTNCAYGGNTCNCARAGYTCN ACNCCNCCNYTNAGYMGNAARTCNCCNACNTCNGAYCARGGNGTNCARGTNCARCCNAAR AGYCCNGARAARTCNAGYAAYGAYAGYCARCARCAYCARCAYYTNCARCAYCAYCAYCAR CARCAYMGNGARTTYCCNMGNGGNCARGGNGTNMGNMGN--------------------- ---GGNGGNGGNCARMGNATGGAYAAYMGNGARMGNATG---------GAYGGNMGNGAY AAYMGNGGNGGNGAYCCN---------------------------MGNGGNGGNGAYCCN MGNGGNGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYCCNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------YTNAARAARYTNTGY TTYACNTGGTCNACNCAYYTNACNGARAARGCNTTYATHAAY---ACNGTNMGNTCNGCN ATHACNCAYYTNGGNYTNGCNGAYMGNCARGARGAYGGNCCNTAYYTNTAYTTYGTNYTN CCNCAYTTYCCNCAYYTNGTNTCNYTNACNYTNAAYGGNCAYAAYGTNTGYYTNGARGAY TGYGARTCNATHGGNMGNTAYTGYAGYAAYATHGTNGARATHGTNTTYGAYGTNMGNGAY GTNGGNGAYGAYTCNTAYACNTAYGCNTAY---ATGCAYCCNAGYAARACNYTNTCNGGN CCNGARYTNCARGTNATHGCNMGNCAYTGYAAYCARYTNMGNAARTTYCAYGCNCCNGGN TCNGARGTNGAYGAYGAYAGYATHGGNTTYYTNTTYAGYAAYTGYCCNTTYYTNGARGAY ATHAAYTTYATGCAYTGYYTNCARYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYTAYCCNGCNGAYGTNGARGTNTCN TAYGAYGAYTTYCAYTAYGTNGARAARYTNYTNCCNTCNACNACNGTNCCNGCNCCNCCN AARCAYGCNTCNTAYCCNACNCCNTCNGGNTGGGTNCCNCCNAAYAAYGARATHMGNTCN CARCARGAYTAYYTNGTNMGNMGNACNMGNAAYCAYGTNYTNCCNGTNTAYCARAARGAR ACNGARCARTGGGGNAARATHMGNCAYYTNGTNACNGTNAARAAYATHGAYGGNAAYATH TGGAARYTNGARGCNGAYYTNMGNAAYTAYYTNTCNGARAARAGYGAYYTNAARGARGTN ATHACNCARGTNCAYGARGTNAGYMGNTGYATHMGNATHMGNGGNYTNCAYACNGAYATH GTNGCNAARTTYYTNYTNGARAARGGNATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CCNTGYYTNGARTGGYTNAARTAY AARTTYGAYYTNAARTTYYTNGGNAAYACNCARATGGAYGTNGAYTGYMGNACNACNGTN GARYTNMGNGGNCARTCNGTNYTNGAYGGNYTNTGYCARYTNACNAARGCNGGNTTYGTN AARYTNCCNATHCCNAARCAYGTNTGYGGNGTNGCNAGYAAYCARMGNAAYCARTTYACN GTNGARATHGARAGYYTNATHCCNYTNCARTAYATGATHTCNAARYTNATHYTNGTNGGN GAYGARAARCARYTNCCNCCNACNGTNMGNTCNMGNAARGCNCARGARTAYMGNTAYGAY CARTCNYTNTTYGCNMGN------------------YTNTGYTCNAARTGYGARAGYCCN ATHATGACNYTNAARGARCARTAYMGNATGCAYCCNGAYATHYTNTCNYTNCCNAAYACN TTYTTYTAYGGNAAYCARYTNATHTCNGCN---GARTGYATHGTNAARMGNCARCCNTTY YTNATGCCNTTYYTNGCNTTYGAYATGYTNAARAGYCARGARTCNCCNGGNMGNGAYMGN TCNTTYTTYAAYGAYYTNGARGCNMGNTTYGTNGCNAARYTNTGYAGYCARGTN------ ---------CARAARACNGCNATHMGNMGNATHACNTTY------------GGNGTNATH TGYCCNTAYAARGAYCARAARGARMGNATHGARTGGTTYYTNMGNGARAGYTCNATGAAR AAYATHGAYGTNAAYACNGTNGAYAGYTTYCARGGNCARGARMGNGAYGTNATHGTNATH TCNTGYGTNMGNGCNCARGARAAYCCNAARACNGTNGGNTTYTGYGAYGAYGGNAARMGN ATGAAYGTNGCNYTNACNMGNGCNAARYTNTCNYTNTTYGTNGTNGGNCAYTTYAARACN ------------------------------------------------------------ ---------------------------------------------------GGNMGNAAR MGNAARAAYACNTTYGARYTNGAYMGNCCNTCNYTNGGNGAR---GGNACNCCNACNATH GAYTTYCARCCNCCNMGNAAR---ACNMGNYTNAGYTCNTCNTTYACNGAYACNCCNGAR TTYAARAARGAYCAYGTNACNAARMGNMGNTGYACNAAYACNTGYGAYATHATHTCNCCN TCNCCNCARGTNGAR---GAYGTNAAYACNGGNGGNAAYTTYAARAARTCNAGYAGYCCN GGNACNAARGCNATGATHGAYTCNATGGAYGGNTCNYTNTCNAGYGCNGARMGNMGNMGN AARYTNYTNTCNGCNYTNAAYAARAARGTNTCNGCNAARGTNCARGCNAGYCCNTAYAAR ATHCCNGCNYTNYTNACNAGYCARATHCCNMGNTTYACNACNYTNATHGCNAAYAARAAR AARCARGCNCARAARCCNGTNACNCCNGGNAAYAARGAYTGGAARCARATHCAYAGYAAR GCNTTYTCNAARTTYGAYTCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGGAYYTN GGNAGYAARTTYGTNTAYYTNGGNAAYGGNGARGARGAYGARGARGARGTNAAYGTNACN GARATHAAYGAYATHGTNYTNTCNGAYAGYGAYTGYAGYGAYGAYGAYGGNGARACNTGY YTNYTNGAYATHTTYGAYACNGCNGGNCARGARGARTAYTCNTCNYTNAARGAYCARTAY GTNAARAGYGGNGAYGGNTTYGTNATHATHTAYAGYATHAARGAYCARCARAGYTTYMGN CARGCNGARTCNATHTTYAARTGGYTNAARMGNGTNMGN---GARGAYAGYATHCAYTGY GTNYTNGTNGCNAAYAARCARGAYYTN------AAYGAYGARGCNATHATHACNCARAAR CARGGNCARGAYYTNGCNTCNAARYTNAAYGTNCCNTTYTTYGARACNTCNGCNAARACN GGNGARGGNATHGAYAAYGCNATGACNGGNYTNGTNCARATHATHCCNMGNTGYGGNAGY GAYTAYAARATHGTNATGYTNGGNAGYGGNGCNGTNGGNAARTCNAGYATHACNYTNMGN TTYGTNAGYGAYACNTTYATHGAYGAYTAYGAYCCNACNATHGARGAYTCNTAYMGNAAR ATGATHTCNGTNAAYGGNYTNACNGGNGCNAGYAARGAYATGYTNAARGCN--------- ---AARAARYTNAARAARMGNAARGGNACNGARGGNGCNGCNCAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ CAYYTNCCNCCNCCNAGYGCNCCNGAR---------------GTNMGNAARGTNAARCAR MGNATGATGGAYGGNAAYGTNATGYTNATHACNYTNAARACNYTNAARGAYGAYCCNAAY YTNGTNACNGGNGAYGCNATHAARTGYGGNCARTGYYTNGCNGTNYTNACNTCNACNGCN GTNYTNCARGGNCAYGGNGARAARAARACNTGGAAYTGYGARTTYTGYGGNCAYTCNAAY ACNGAYYTNGARATHGARGARGAYGARGTNCCNAARGGNGARTGYYTNGAYTAYATGYTN TCNCCNGCNACNAARCCNAARTCNGARGAR---ATGGARTGGGARGARGCNAARGARGTN AARAARGARACNACNCCNGGNATHATHGTNTAYTGYATGGAYATHAGYTCNTCNATGCAR GCNAAYTGYGARATHCCNGARTCNCAYGTNGCNTGGMGNGARGARMGNCAYGGNTCNGAR ACNATHAAYMGNGTNTCNMGNYTNGAYTGYATHCARAARGCNGTNGARMGNYTNGCNAAR CARYTNAARYTNGARCARCCNGARAARCARGTNYTNYTNACNGTNTTYAGYTCNTCNGTN TAYGTNAARGGNGGNGGNAAYGCNGAYCAYYTNCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNGTNTTYGGNACNYTNTAYCCNGCNTAYGCNTCNTAYAARGCNGTNMGN ACNAARAAYGTNAARGARTAYGTNAARTGGATGATGTAYTGGATHGTNTTYGCNYTNTTY TGYTGYATHGARACNTTYTCNGAYGTNTTYYTNTCNTGGYTNCCNTTYTAYTAYGARYTN AARATHATHTTYGTNYTNTGGATGYTNTCNCCNATGACNCARGGNTCNAGYTTYYTNTTY AARAARTTYGTNCAYCCNCARYTNGCNMGNMGNGARAARGARATHGAYGARATGATHATH CARGTNAGYMGNCARGGNTAYAGYACNYTNYTNTCNYTNGGNACNAARGGNATHTCNTAY GCNTCNCAYGTNATGATGAARACNGCNGTNATGGGNCARTCNAARYTNGTNGAYCAYYTN MGNMGNAGYTAYAGYACNAGYGAYYTNTCNGAYGAYGGNCARGCNGTNATGCARMGNCAY CARGCNGTNAGYGAYGARGARGGNGARGAYGARYTNGAYAAYMGNYTNMGNGARGAYAAY GARGARYTNGARATHTCNAGYTTYAGYTCNACNMGNGTNCARMGNGTNTCNMGNATHAAY AGYATHGARTCNACNMGNYTNAAYCARGAYATHMGNYTNGTNTCNATHTCNYTNGAYTAY ATHCARTCNTCNAGYGGNCAYAGYCCNGARGCNTGGAARCCNTAYCAYGTNGARGAYGAR GARGCNACNACNGAYGTNAARGCNGARAGYCCNTGYTTYATGTAYGGNGARMGNATHYTN AGYMGNAARATGMGNMGNGTNCARMGNCCNATGTCNGCNGTNGARMGNGCNTGGCCNAAR AGYAGYCCNGAYAARGARMGNCAYGTNAGYACNYTNATHTGGTCNMGNATHMGNGAYAAY AGYAAYGAYGAYCAYGAYTTYATHAGYTCNTCNACNTCNTTYACNAAYGCNGAYAAYATH TCNCCNAARGARGCNTGGGARAAYGAYACNTCNGCNATHACNAARMGNATHYTNAARTCN CARGCNTGYGCNCARTCNGGNAARMGNCARTCNGTNTAYATGTCNGCNAGYGAYGTNATG ACNTCNCARTCNTCNAARAARGTNMGNGGNYTNGCNMGNAARATHMGNYTNTCNTCNACN TCNGCNAAYTCNAGYMGNCCNACNTCNACNATHCCNMGNCAYGTNTCNTCNCARCAYGGN ACNGGNGCNGAYAARTCNCCNCARTCNTCNAGYGCNACNTCNACNAARGCNACNATHGGN GARATHYTNAGYCARCAYMGNCCNACNYTNAAYGCNGGNGARTGGMGNAAYCAYYTNAAR AAYAGYYTNGCNACNCCNATHTCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYTCNGAYGCNCARATGGARGCNGCNGGNMGNACN CARATHTTYAARGAYTTYCCNMGNMGNMGNTCNYTNTTYGAYATGCCNGTNGTNACNACN YTNTAYTAYTGYTGYYTNTAYCAYTAYGAYYTNTCNGARAAYTCNYTNGCNAGYCCNATH GCNATHAARAARMGNCAYCARGTNTCNGAYAARCARTTYATHMGNACNTGYATHGGNGCN MGNGCNAARYTNMGNCARTGGAARGAYATHGARGCNGTNYTNACNACNAARGGNTGGTTY GGNGGNACNAARYTNAARTCNGTNATHGGNTTY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNGCNGCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TCNCCNTCNYTNGAYATHAAYCAY MGNAARAARMGNGCNATHGTNMGNCAYYTNAAYTAYATHAAYCAYGARAARACNYTNAAR CAYAAYTAYAGYCCNYTNGTNTCNYTNCCNGAYTAYTCNTAYGTNGAYGGNMGNCCNACN GARATHATGYTNTCNCARAARYTNMGNGARGARAAYAAYTTYCARYTNGCNAARMGNGTN GTNCARYTNGTNGARGARATHAARYTNGCNCARAAYCARYTNAARAAYGAYGARAARGCN CARAARGAYTAYTTYMGNCARCARGCNGARTCNMGNYTNCAYGTNAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TTYMGNATHACNTGGGAYCCNCAYTCNCARCCNTTYYTNTCNACNACNGTN AARTTYACNYTNAARGAYYTNGTNTCNTCNGCNTAYCAYYTNGAYAARGTNTCNCCNACN CAYCARATHATHYTNCAYCAYTAYYTNCAYYTNACNCCNTTYCAYTTYAGYGTNATHCAR GARMGNTAYCARTCNYTNAARCARGCNATHCARMGNYTNYTNTCNMGNAAYTCNAAYGTN MGNATHGCNATHCARGGNCCNCAYATHTCNTGGGARGGNTGGCCNGTNCAYGCNGGNGGN GAYCAYYTNGGNAARTTYATHATHMGNAARCARAARGARATHTTYMGNGARYTNCAYGAY AARGTNTTYTAYATHAAYACNTGGGAYATGACNGTNGCNGAYGCNAAYATGAAYTTYCAY ATGTCNYTNGAYATHGTNTCNAARTCNYTNGAYATGGAR------GARACNGGNAGYGTN MGNTCNGGNAARGCNAARMGNAARATGAARYTNGCNGARAARAAYGCNATGAAYYTNATH AARACNGAYMGNCARGGNGTNTGGAARGARYTNMGNAARATHCARAARAARAARCARAAR GARGTNATHCARAARMGNGARAARCARGTNYTNAARTCNGCNATHGARAARTAYAARGAR GARAAYAAYTAYGAYAAYACNGARMGNAAYATHAARGCNYTNYTNCARGTNACNCARYTN TCNAARGTNAARGAYGARGCNGCNAARAARATHYTNTAYCAYCARCCNTGYMGNYTNTCN MGNGAYATGGARAARATGACNGTNACNAAYGARAAYGGNAGYATHTTYACNGARGARGAY TTYGARAARTTYGCNAARGARTAYCAYCCN------------------------YTNGTN GGNGGN------------AAY---CAR---------------------GARMGNCARAAY MGNAAR---YTNYTNGARCAYATHCARGARCARAARAARMGNYTNCARCAYGGNCAYCAY GCNACNCCNAGYAGYTCN---GCNAGYYTNATGAGYGGNGGNGGNGCNTCNCCNATGYTN TCNAGYCCNTCNTCNGTNATHGGNATGTCNCCNGCNGARTAYGCNAGYATHAGYAAYCCN CARCARMGNGCNGCNYTNCARCAYGCNCAYGTNAAYTCNGTNGGNTAYTTYATHACNCAR GAYTCNTCNTTYGGNAAYYTNATHYTNCCNGTNYTNCCNAARATGCCNGARATGAARCCN GAYGCNAARGGNGGNTAYCCNYTNAAYCCNGGNCCNTCNCCNTCNAARCCNGGNGGNYTN GCNMGNGAYAARTGYATHATGGCNAAYGGNYTNGAYGARGCNYTNTGYTTYTCNTTYMGN ACNGAYAAYAGYGGNCCNCCNATHAAYATHTCNGARGTNYTNATGACNTAYGARATHYTN MGNATGGARTTYCCNGGNGCNMGNYTNTTYGCNTCNACNATGGAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYMGNTCNAARCAYMGNCCNGCNMGNAARGARTCNAARMGNGARAAY YTNGCNAARGTNMGNAARAGY------GAYAARCAYGARAARAARGAYGARCAYGTNGAR AAYAARGAYGARGGNACNTCN------AARAARGGNMGNGTNTCNYTNTCNTTYTTYGAY MGNYTNTCNACNCCNAARTTYAGYMGNGGNCARACNAGYGAYYTNCCNAARGAYATHCCN YTNAARAARGARTCNCCNATHATHMGNYTNYTNCCNMGNAARGCNTTYTCNACNACNAAY YTNGCNACNATGAARAARMGNTCNTCNYTNMGNGARAAR--------------------- ------------------------------------AARGAYTCNACNCCNMGNCARTCN TCNACNACNGGNAARGAYATHMGNGCNCCNTCNCCNAARCAYATGACNCCNACNACNTCN AARTCNACNGCN------TCNCCNMGNMGNACNCCNCCNCCN------------------ ---CCNTCNTCNGCNGCNGCNTCNACNTCNCCN------CARCAYAGYGTNACNGGNACN AAYCARGCNCCNGARGAYGGNAAYACNGCNCCNMGN------AGYGTNAAYYTNGGNATH ACNGARGARGCNTAYAARGCNAARYTNGCNGARAARMGNMGNCARGCNMGNGARAARGCN GARMGNGARGCNGARGARGARMGNAARAARCARGARGARGARMGNYTNGCNGARGARGAR CARYTNMGNCARGARGARGARGAYCARMGNTGYATGGARGARGARTCNAAYATHYTNGCN GARGTNGCNMGNAARTCNGARATGGARMGNYTNGARMGNGCNATHGARGCNGARGARAAR MGNAARAARGARGARGCNGAYMGNYTNGARYTNGARMGNAARGCNAARGARGARGCNGAR MGNAARGCNAARGGNGARGCNGARAARYTNGARAARGARAARCARGARMGNGCNAARAAR GARGARGARGARMGNYTNCARMGNAARAARAARYTNGARATGATHATGAARMGNGTNAAR ACNGAY------------------------------------------------------ ------------------------------CCNACNCARGAYACNATHMGNTCNACNGCN AGYTCNCCNGAYTGYCARGAYAARYTNCCNCCNTCNCARGARGCNCCNGCNTCNGARGCN ------------------------------CCNGTNGARGAYCCNTCNMGNGARATGGTN ACNTCNTCNCCN---------ATHYTNCARACNTCNGAYGTNCARGAYGARGARGAYTGY CCNGTNACNCCNGGNAAYTGGTCNTCNTCNACNACNGAYGGNACNACNGCNACNTCN--- ---------------GTNGCNMGNAGYGCNTCNTCNGGNAAYATHYTNGAYGGNGCNTCN GCNTAYGTNGARGCNAARGARMGNGARAARGARGAY---GCNATGAGYACNAGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARATHCCNAARGGNGCNAAYYTNAGYAARAARGAYGAYYTNTAYYTNCAYGTNYTN GGNYTNTGGTCNGAYGARCCNATGGCNAARYTNGGNAAYATGYTNTAYGCNGGNGARGTN MGNAGYCCNYTNGGNACNTAYYTNATGGTNGGNYTNGAYAGYMGNGAYATHCARCARMGN MGNGCNAAYGCNGAYMGNGARATHYTNYTNGCNGAYMGNTCNYTNMGNYTNCARCCNATG TAYTTYACNMGNAARATHGGNTCNGAYGGNCARGTNATGGARTCNMGNTCNATHTGGMGN YTNTCNATHGTNTCNGARACNTTYTGGGGNTTYATHAAYTTYATHGTNYTNTTYTTYCAR ACNATGGTNAAYCCNAAYAARAAYTGYAARGGNGAYAGYTAYACNACNGAYTAYMGNMGN CCNGGNGGNGGNGGNCCNCCNAGYMGNMGNATGGGNGGNTTY------MGNMGNGGNGGN GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CARGCNTTYACNTCNGTNAARCAY MGNYTNGAYTCNTCNYTNTCNAAYGAYGARGAYTCNCARMGNTAYYTNTTYGAYGARGCN MGNGTNAGYGCNAGYACNATHYTNYTNCARYTNAGYMGNATHATHTAYTTYTAYGAYAAY ATHTGYAAYCAYATHCCNAARTCNYTNGARTAYCARYTNATGTGYAAYTAYTAYGARYTN ACNATGGAYGTNCARCARGTNCCNMGNGARTGGCARACNATGGCNATGAARGARACNTAY YTNCARMGNACNAAYGARGTNCARAGYGAYGARGAYYTNGAYAARGCNAARAARTTYYTN GCNAARGGNGTNGCNGGNYTNCCNGARATHGTNGARAAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNTCNTAYGCNGAYYTNATHACNAARGCNATHCARAGY TCNCCNGARAARMGNYTNACNYTNTCNCARATHTAYGAYTGGATGGTNCARAAYGTNCCN TTYTTYAARGAYAARGGNGAYAGYACNAGYTCNGCNGGNTGGAARAAYTCNATHMGNCAY AAYYTNTCNYTNCAYAGYMGNTTYATGMGNATHCARAAYGARGGNACNGGNAARAGYTCN TGGTGGGTNATHAAYCCNGAYGCNAARCCNGGNAARACNCCNMGNMGNMGNGCNGGNAGY ATGGARACNAARAAYTAYGARAARAARMGNGGNMGNGTNMGNAARAARGTNGARGTNYTN MGNAAYATGGARAAYGGNGGNGGNYTNTCNTCNAGYGTNAGYGAYGAYTAYYTNGAYAGY TAYGGNGAYTTYMGNCCNMGNGCNAGYTCNAAYGCNAGYAGYTGYGGNMGNYTNTCNCCN ATHCAYGCNGCNGCNGARCCNGAYYTNCAYGARAAYCARGTNCCNCCNATGTCNCCNATH CCNTGGGTNGCNGARGTNAAYAAYTCNCCNACNYTNTAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARATHGTNYTNTGYATHYTNATHYTNATHTGYGCNTCN GTNACNGAYTGGTAYAAYATHGGNGGNGGNTGGGTNCARTTYGTNGCNGCNTCNGCNATG ATHACNACNGCNATHYTNTTYATHTTYCAYYTNTTYAAYYTNATGYTNMGNYTNCCNGGN CAYTGGACNTTYATHGARTTYATHTAYTAYTGYGTNTTYTGYGTNYTNATGATHACNGCN GCNATHGTNTGYTCNATHMGNGCNCAYYTNACNCCNGCNATHGGNGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARMGNCARAARCARGARGARCARTCNMGNGARTCNTTYATGAGYMGN ATGMGNAAYAARTTYTCNGARMGNAAYGTNGARMGNGAYATHAARGTNGCNCARAARGCN TGYYTNCAYYTNGAYCARCARCARGCNATHAARGARCCNMGNGARGGNTTYTTYTGGCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TAYAAYACNGCNYTNGAYATGYTNYTN TGYTGYGCNTCNGTNATHYTNGCNTTYCCNAARTCNACNACNGCNGGNYTNMGNMGNAAY YTNTCNTTYCARACNAARAARYTNAAYTCNGTNYTNGARGTNAARAAYMGNTCNGGNTCN AGYTTYGGNCAYGAYYTNAAYGCNYTNAARMGNTAYYTNCARGCNTCNGAYTTYYTNCAR AAYGTNGTNTAYATHACNYTNCCNACNCARGARGAYGAYMGNATHCARMGNTAYATHACN YTNTCNTCNYTNTAYAARCARYTNGGNTTYCARMGNAARGCNGCNTTYTTYAARMGNATH TGYGGNATGCAYTGYGTNGTNCCNGARAAYTCNCCNAGYTGGTCNCARTGYCAYGARYTN YTNYTNCARTGYNNNGARGGNTAYGGNYTNTCNATHGAYTCNAARGARATGAARAARGGN CAYCAYMGNGGNTGGCCNGCNYTNCARTGYMGNGTNYTNCAYGARYTNGTNTAYGCNGCN MGNCAYATHAAYTGYCCNCARGTNGCNGTNMGNCAYATGACNYTNYTNGTNCARYTNATG YTNCCNCAYYTNTCNGTNAAYGARCARMGNGARGCNYTNACNAGYYTNTCNACNYTNACN YTNAARTGYCCNGGNGTNCCNCARCCNATHGCNTGYGAYAGYGGNGTNATHYTNCCNCCN GTNTCNYTNYTNYTNYTNCCNTCNGTNMGNTCNTTYAARYTNYTNCCNCCNAGYCARCAY YTNCARCCNCAYMGNGARGARACNGGNCAYGGNTCNGGNACNGCNCARGTNTTYATHTAY TCNCCNTTYTCNTCNCAYAGYAGYACNGARGAYGAYAGYAARCCNGAYTTYAARTGGGTN TGYGGNGAYGTNTGYGARGCNTCNGTNCARYTNGTNAAYCCNYTNGCNGAYGARYTNAAR ATHYTNTAYYTNGGNYTNGTNACNTCN---GTNGARACNGARATHATHCCNGCNAGYCCN ATHYTNCCNCCNGAYTCNGGNCCNATGAGYGTNAARYTNATGYTNAARCCNAARACNGTN GGNACNYTNAAYGTNTCNGGNTAYACNTCNGTNGTNTTYGGNGTNAARAGYAAYTGYMGN YTNTGYGAYYTNACNGCNYTNAARCCN---CCNATHACNGARATHAGYATHGAYATHATH CCNGCNATGCCNCARATHGTNYTNTCNTGYTCNYTNCCNAARTCNACNATGTTYACNTCN GTNGGNAGYGGNGCNAAYGTNGTNACNTCNGGNTCNGCNGTNYTNTTYGCNGGNCARMGN ATGGARTTYATH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATH TGYGARATGAAYTGYGAYGTNATHGTNTCNCCNACNGAYAGYMGNATHAAYCAYCAYGGN YTNGCNTCNATHATHGCNTCNAARGCNAARYTNCARGAYGARTGYMGNMGNTAYATHACN AGYGCNGAYCCNYTNAARGTNACNGARYTNTTY---TCNACNGCNGGNAAYTTYAARGCN AARMGNGTNTAYCAYGTNYTNGCNCCNTTYTGGAARTTYTAYCCNGAYGAYATGATGMGN TTYAARMGNGAYGTNATGAARACNATHYTNMGNTGYYTNATHAARGCNGARYTNGAYAGY TTYTAYTCNATHGCNTTYCCNTGYATHAGYTCNGCNGTNGCNGARAAYGCNYTNCAYTTY TGYTTYCARGGNTAYATHATGGCNGTNAARATHTTYGAYCAYTTYCARYTNAARMGNTCN YTNAARGARATHTTYTTYGTNGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GTNGTNGGNGAYGTNGARGCNAARTGGAAYGAYYTNACNGARYTNYTNGTN CARCARGTNTCNYTNGARGCNYTNTCNGARATHGAYGGNATGYTNAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNCARGGN------------------------------------------------ ------CCNMGNGARAAYMGNNNNGGNMGNGTNGGNGAYGARAAYGTNCCNCCNGARTTY MGNGARMGNCCN---GAR---AGYTTYAARMGNMGNGARGAYMGNGGNGAYMGNGARGGN GGNTTYGGNGGNGARMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNMGN---GGNMGNGGN GGNGARMGN---GGNGGNTTYGGN---GGNCCNMGNGGNGGNTTYGGNCCN---GGNGAY MGNAARMGNGARTTYGAYMGNCAYAGYGGNACNGAYMGNACNGGNGTNAARCCNGTNGAR AARMGNGARGGNGGNGGNGCNCAYAAYTGGGGNAGYTTYMGNGAYTGYATHGARGARCCN AAYCARGCNAAYACNGCNGAYGARTCNGCNGAYTGGACNCCNCARCARGARAAYACNGCN GARAAYCCNGARCARAAYGARACNGGNGARACNGARAAYGTNCCNGARGARGAYYTNCAR CCNCARGARATGACNYTNGAYGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GARCARAAYCCNGGNGGNMGNAARATGTTY YTNTAYTCNGGNCCNGTNMGNTCNAARTCNMGNCAYCARGARGAYTGGCCNTTYGGNCCN AARTCNGTNAGYCARACNGCNAGYCCNMGNTCNGGN---TCNATHAAYYTNGAYGAYGTN TGGAGYATHMGNAAYGTNGGNYTNGGNAAYAGYAAYCARYTNATGAARTCNGARCCN--- ---YTNAARTCNGARAGYYTNAGYAARAAYACNAAYCCNGCNTTYTAYTCNMGNCAYAGY GGNATGAARGGNGGNAARGCNYTNAGYACNMGNGAY------GGNAAYGGNAAYTCN--- GGNGGNATHGGNTCNAARTGGACNAGYTCNGGNCAYAAYTTYAGY---CARGCNTCNMGN ATGCARCCNCCNGCNTCNCARAAYCCNCCNGARMGNGGNTTYMGNAAYCCNAARCAYCCN AAYCARAAYCCNGCNCCNTTYGAYTAYGAYGTNAAYGAYTTYATGGCNYTNAAYMGNTCN TTYATHATHGGNGTNAGYGGNGCNACNAAYAGYGGNAARTCNTGYACNGGNTCNMGNYTN TCNAARGTNYTNCCNAAYTGYACNTGGATGTGYCARGAYCAYTAYTTYYTNGCNGCNGAY GAYCCNMGNYTNGAYYTNGCNGARAAYGGNATGACNAAYTGGGARATHYTNAGYGCNYTN GAYATGGAYACNATGTTYGAYGAYGTNAAYGCNTGGATHGARAARCARAARTCNTCNTCN TCNCCN------TCNTTYYTNGTNATGGARGGNTTYTCNATHTTYAAYTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATGCARATHMGNTTYAARAAYAGYAARCCNMGNGTNAARGARGCNAARGTNCAR GTNGAYAGYAAYATHMGNTAYATHCCNAARAARAARMGNMGNAARGCNGCNACN---GCN AAYATHGTNGTNGTNGARAARGAYACNATHATHGCNGARAARCCNGTNGAYAAYGTNTGG GTNMGNAARTTYTAYCCNMGNCCNMGNTTYTCNATHGARGARGCNATHAAYMGNCAYAAR TCNYTNGCNCARCCNGAYATGYTNGAYAAYATGGAYGGNYTNATGTAYYTNAAYATGAAR YTNGAYTTYMGNACNAARAARCARACNAARTTYATGAGYAAYGTNMGNTCNACNYTNYTN YTNCCNCAYGTNTTYCCNTGGGGNCCNCCNCCNTCNATHYTNGTNTTYAGYAARGCNGAR GARTAYGTNAAYYTNGCNATGTCNYTNGGNGCNAARCAYGCNGGNGCNCCNGCNACNGTN ATHAARYTNATHGARAAYGGNATHYTNAAYCCNAARGAYTTYAARCAYGTNYTNGCNACN GCNGAYTGYGCNAAYGARATHYTNCCNGCNMGNACNCAYTTYMGNGAYMGNTTYCCNCAR MGNGCNAARGGNAGYGTNAGYACNGAYYTNAAYGARATGTGGAAYYTNTTYTAYACNGGN TAYACNTAYGARTCNCARAARYTNACNGARTCNCARGGNAARYTNCARGTNCCNYTNGGN CARYTNAARCARCCNGTNAGYGARYTNGTNGCNAAYTTYGARGCNTAYATHCARTCNGTN TGYCARCAYMGNAGYATHGCNTCNGGNCCNTTYGTNCAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TAYGTNATHGARTTY GARAAYCCNGARGARCARGAYGAYGGNTGGCARYTNGGNATHAARCARTCNGAYGGNAAR AARGGNGTNTTYCCNGARAAYTTYACNAARAARATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CARTCNAARGTNCAYYTNATHTTYCCNTCNAAR GAYAAYATHMGNYTNTCNYTNGARGGNTAYAAYGGNGGNGGNTCNGTNCCNTAYAGYATH AARACNGCNGCNAARCARCCNTGGYTNGTNCCNTTYYTNTGYCARTGGAARTCNAARGGN MGNGGNMGNTCNAARGCNGTNCCNCAYATHAARTCNTAYACNMGNTAYTCNCCNGAYGGN ACNCARGCNGCNTGGTTYTGYYTNACNAGYGCNAAYYTNTCNAARGCNGCNTGGGGNGCN YTNGAYAARACNAARAGYGGNYTNATGATHMGNTCNTAYGARYTNGGNGTNYTNTTYYTN CCNCARCAYTTYGAYTGYCCNAARGCNYTNAAYGTNAGYAGYGARATHGAYAARATHYTN GAYCCNGARMGNAARGTNTTYCCNYTNCCNTAYGAYYTNCCNCCNTCNACNTAYGTNAAR GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATHAAYTAYGGNYTNTGGAARATHTGYYTN TCNGGNCCNTCNGCNMGNAARYTNTGYGCNAARTGGGCNAGYGARACNAARGTNGGNTCN GAYGGNCCNGAYTAYGCNATGGGNGGNTGGATGAARGGNTCNCARGCNATGGCNATHGTN GGNYTNYTNATHGCNGCNGCNGCNGCNGTNCARGGNATHATHAAYATHYTNGTNCCNAGY MGNGGNGAYMGNYTNMGNYTNYTNCCNATHTTYATHTGYGTNACNGGNGTNGCNGGNGGN ATHYTNGTNYTNGTNGGNGAYATHATHYTNGCNTTYAAYTAYGAYACNATHATGAARTAY ATHATHCCNGCNGGNATHCCNGCNGGNYTNGTNAARATHATHGARAGYCARTTYTTYYTN AGYTGGGGNTTYGCNYTNGAYGTNGTNGCNGCNACNYTNATGYTNGCNGGNAGYATHGCN CAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GCNGGN CCNGCNAGYCCNTAYAAYCCNTAYATHNNNNNNNNNATG---------CCNACNGCNATG ACNACNAAYGGNGARACNAAYGCN---ATHYTNTCNCARGCNYTNNNNCAYNNNATGNNN NNNGCNAGYNNNAARNNNNNNMGNGCNGAYAARTTYGARACNTCNACNGARAAYGGNGAR ACNYTNACNYTNAAYTCNCCNYTNYTNGAYNNNYTNGGNTAYCCNGCNTAYTTYACNCAR NNNNNNTCNATHCCNGGNGCNGTNCCN---TAYAARMGNTTYGCNGTNGGNGAY---ATH GGNAARGGNGGNATHCCNYTNTAYCCNAGYAAYGCNYTNGTNTCNCCNTTYCARCAY--- ---CAYTCNYTNATGCARTTYCARCARCCNCCNTCNTAYATHCCNGTNCCNTTY------ ------------------ACNGGNCAYGCNCCNAGYGTNCCNMGNTTY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TCNACNGARGGNATHAARATHTCNTGYCCNGTN TGYATGGAYGAYGTNAARCARATHMGNMGNAAYAARMGNCARGTNATGTCNACNACNTGY GGNCAYATHTTYTGYGAYGARTGYATHMGNGCNGCNATHAGYGCNCARMGNTCNTGYCCN CCNTGYMGNAARCAYYTNACNACNMGNAGYATHCAYCCNYTNTTYGTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY GAYCCNAARYTNTCNAGYCARAARGCNATGTTYGGNAARGGNGTNTAYGGNGCNGARTAY TCNGTNAARTCNGAYCARTAYGCNGAYGAYTCNCARAAYMGNGCNCCNGCNGGNACNMGN YTNTCNATGTTYYTNATGMGNATGYTNYTNGGNGAYACNTTYGTNTGYACNGARCARCAY CCNACNATHCARGGNGGNATHAGYGAYAARYTNAARMGNCCNCCNTGYCARAARTGYCAR GARGAYTAYTGYMGNTGYCAR------------AGYACNAARTTYTCNGTNATGGGNGAR GGNATGTGGATGTTYMGNGARATHACNTAYTAYMGNGAY--------------------- ---------------------GAYGAYTCNMGNCCNGCNTTYATHMGNCCNCARTGYTGY GTNGGNATHTAYYTNGAYGCNATHGAYGCNMGNCCNGAYAARAAYACNGTNGTNGGNTCN CAYCAYGCNTTYATGATGGCNGTNATGGAYMGNATGYTNGARCAYTTYYTNAGYYTNGAY YTNGCNMGNGTNAARGGNYTNYTNGARACNMGNCAYGTNGGNGAYGGNTGGATHATHGAR GGNTTYAARACNGGNTGYATHATHGTNGTNAAYTTYGAYACNAGYACNAGYYTNGARGAY YTNTGGATGATGCAYAARAARAAYMGNYTNTCNGCNATHYTNCARGAYGCNYTNGTNGAY MGNGCNYTNYTNAARGCNACNAAYACNGTNAARYTNACNYTNMGNTCNAARCCNTGGGAR GAYGARATHATHGCNTGYMGNCARGARYTNCARTCNTGYGAYCCNGCNMGNATHAAYGTN GARMGNAARGARMGNGAYYTNGCNYTNGCNAARMGNGTNMGNCARTAYCARAARGCNATG CCNAARGCNATHATHGAYGCNMGNGAYGCNGARAGYATHYTNGARMGNAAYYTNGGNAAR YTNATGYTNACNATHAARCARGTNYTNCCNCAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GGNATHTCNACNCCNAGYGGNATH CCNGAYTTYMGNACNCCNGGNACNGGNYTNTAYGAYAAYYTNCARCARTAYAAYATHCCN TAYCCNGARGCNATHTTYGAYATHGAYTTYTTYCAYCAYAAYCCNMGNCCNTTYTTYGCN YTNGCNAARGARYTNTAYCCNTCNGGNAARTAYMGNCCNAAYTAYATHCAYTAYTTYGCN MGNYTNYTNAAYGAYMGNGGNATGYTNGAYAARYTNGTNGARGCNCAYGGNACNTTYGCN TCN---------------------------CCNAARCARYTNGGNTGYAARYTNAGYGCN GARAGYYTNTCNYTNATHCARTCNACNGAYAARATHGAYMGNAAYGGNMGNGTNTGGGAR GAYGGNGARGTNCCNTCNTCNCAYAGYGARGARTCNGAYAARGARAARAGYGAYTCNGAY TGYGAYAAYAAYYTN---TCNGARACNGGNTCNATHGAYTCNAAYGCNGARGARTGGMGN CCNMGNTCNGGNAARCAYAARAAR------AARCAYAARCAYAARCAYAARAARAARAAR AARTCNAGYAARGAYMGNGAYAARACNAARGGNAGYGARMGNAARAARYTNCAYGARTCN GGNACNGARAARGAYGGNCARGAYAGYAARTCNGARATHAARGTNGGNGAYGTNAGYCAR GCNGCNAAYGAYAARGAYAARGTNGAYGARCCNGARAARTCNAARAARMGNAARMGNGAY AARTCNMGNTCNCCNAARCAYAARAARMGNTCNMGNAGYMGNTCNTCNMGNTCNCCNAAR CAYMGNAARAARTCNGGNAGYCAYTCNMGNTCNAARTCNCCNAARTAYMGNAARMGNTCN MGNAGYCAYTCNMGNTCNMGNTCNCCNMGNAARAARAARMGNMGNAGYCAYTCNAARTCN MGNTCNAARTCNCCNMGNAARAGYAARMGNGARTGYAGYCCNAARMGNTCN--------- AGYTCNCARAGY------------------CAYTTYAAYGARTGGGAYGCNMGNMGNTAY AGYGAYGAYCCNAGYAARTTYTCNMGNGARMGNCCNYTNTCNCCNCCNGAYTCNATHMGN AARAARMGNGAYCAYGAYAGYGAYYTNMGNYTNCARATHGAYAARGCNAARYTNMGNAAR ATHGCNATHACNAAYGCNYTNAGYAAYYTNAARTCNGGNCARGGNCCNCARYTNGAYATG ---------GCNACNAARGCNGGNGGNAARTCNGTNGARGARYTNACNGAYTTYTGYAAR MGNATHTCNGARAARGAYMGNGAYAARGAYAAYAAYYTNGTNGAYAGYAGYGAYGARGAR ACN---GCNAARAGYGAYGARGAYGARATGCCNATHCAYCAYCCNTTYAARGTNAARGAR GCNTCNAGYAAYATHGTNATGAAYATHMGNAAYGCNAARCARYTNCCNATHYTNACNCCN TCNGARAARCARGCNCARCARGCNACNYTNMGNYTNGCNTAYCCNGTNTCNAGYGGNACN CAYCAYMGNGCNAGYGARTCNGARTGGGTNCCNGTNGAR------------------AAR ACNGTNGCNGCNACNTCNGCNTCNGAYACNAARGCNGCNACNYTNCARGCNCCNATHTAY CCNCCNGARGTNGARGARAGYATHTTYCCNACNGTNAAYGARAAYATHGAYATHGGNTCN ATHATHTCNGARMGNATHCARGCNGTNMGNAARYTNCARGCNAAYCCNTAYGAYGTNCAY GCNYTNAGYACNATGCAYAARGCNCARGARAARGCNAGYCARTGGGCNACNTCNAARCAY YTNCCNGGNCARTTYATGGGNAGYACNGGNGCNCARGTNYTNTCNCARCARGARYTNATH GGNGAYAARMGNAAYCARGCNTGGGCNMGNAARTCNCARTTYGCNAAYGCNGCNCCNYTN AGY------------------------------ACNCCNATGGARAAY------------ ------------------------------------------------------------ ---------------------CCNAAYAARGCNAARGCNAARCCNCARGGNTAYCAY--- ---------YTNAAYGTNCCNMGNGCNAARGAYYTNAARCAYCCN--------------- ---------------------------GTNTCNATGTTYATHACNGTNATGGARGAYGGN CCNGAYCAYAARAARAAYTTY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNCCNCAYYTNTCNTCNMGNGAYYTNACNAARGTNGGNGCNGAYGGNGARGTN YTNGTNATHCAYAAYGTNACNMGNTAYTGYGGNGAYAGYTAYGARTGYGTNGCNTTYAAY GGNGTNCCNCCNGCNACNAGYMGNATHATHGARGTNTTY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CARYTNAAYCARGTN GTNACNGTNGAYMGNGAYAGYMGNMGNGTNYTNCCNYTNCCNGAYTGGTTYAARGAYAAR TAYCAYGGNAARGGNGTNYTNAARGARGGNYTNYTN------CCNYTNCCNMGNCCNGAR AAYACNTTYGTNCAYAARGTNCARGTNCARTGGGCNGAYACNGAYATHAAYGAYCAYACN AAYTTYGTNAGYTAYTCNAARTTYGCNGTNAAYGCNYTNCAYGCNGCNYTNYTNAAYAAR AARYTNAARGARGTNGAYTCNTGYGAYGAYGGNGAYAGYGCNTCNTAYACNMGNCCNYTN GTNTTYGCNYTNAARGAYTTYGAYGARGCNYTNGCNYTNAAYGGNYTNAARCARGTNGAR ATHTGYTAYYTNAGYGARAGYACNGARGGNCARATGYTNGAYATHCAYGTNTGGCARGAR GAYGGNGAYMGNGARACNGTNATHTGYTCNGTNAGYAARAGYGAYGARATHCARATHAAR TTYGARTAYTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNYTNGTNCARGCNGARGARYTNGGNTGY GARGGNAARGTNGARGARTCNCARGGNGTNATGAARYTNGTNGAYCARYTNAARGARGAR MGNCAYYTNYTNGAR------ACNCARCCNGCNCARGAYGAY---TCNCAYATGATGAAR CARATGGARGTNTGYGAYGTNTGYGGNGCNTTYYTNATHGTNGGNGAYGCNCCNCARMGN CARGAYGARCAYYTNATGGGNAARCARCAYGCNGGNTAYGCNCARGTNMGNTCNGARGTN GARMGNMGNAARAARAARGTNAARGAYGARGCNGARGCNMGNGARGCNAAYGARGCNMGN YTNAARAARGARMGNGARGARMGNGARAARGARMGNCARCAYGARMGNGARGARAARMGN CAYMGNGARAARGARMGNGARAARGAR---------GAYMGNGAYAARAARMGNAARAGY GTNAGYATGAAYGAR------------AARMGNMGNGGNACNGARAARAARAAYGARMGN AARMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGAYTTYGAY TCNTCNTCNAARTTYATHGCNTCNYTNGCNAARTTYYTNCARTCNYTNTGYAAYGGNTAY GTNGARTTYGAYAARGGNGTNGARGTNATHGGNCAYATHTAYYTNAGYGTNGAYAGYGAY ACNGGNAARAARATHGAYTAYGTNYTNAAYGARAARGTNAGYAARAAYGAYAAYTCNGTN ACNTTYATHAGYAAYAGYTTYCAYGCNCARCCNGCNGARAARCCNAARCCNCCNCCNAAR AARTCNGARYTNGARTCNAGYAAYGARGAYTCNGTNGTNYTNGAYGAYTCNGGNCARACN GTNCCNAGYAGYACNAAYGTNGGNACNGCNGGNCCNATGMGNATGCCNAAYGGNCARGAY GGNTCNTTYTCNCCNGGNAGYAARMGNCCNMGNTCNCCNTTYCAYMGNAARGGNGGNATG AAYMGNAGYTCNAAYAGYCCNGCNTCNMGN---TCNMGNTAYTCNGAYTCNGGNGGNCCN GGNAARATGCCNMGNACNGAYATHCCNTCNGCNGGNGGNAAYYTNAAYTCNGGNGARGAY TAYGAYGGNAGYGGNTTY---ACNGGNCAYGARGARGAYGAYGGNTAYCCNTCNAAYTTY YTNCARCARGAYCARAAYGCNTCNCAYGAYYTNGAYCARAARCCNGTNATHGAYCCNGAY ATHAGYATHGTNAARGARGARTAYATGACNAAYCARCARGCNAAYATHCCNCCNTCNAGY AAYCCNCARCCNGGNGGNCCNGGNMGNGGNAARGGNCCNAGYTCNTCNCARGCNTAYCCN ATGATGATGCAYGARAAYTCNAGYTAYTCNTCNTCNATGCCN------CCNCAYTCNGCN GAYTCNTAYTCNAGYTCNCCNATHGARGGNTCNGAYCCNTCNACNYTNACNMGNGCNCAR CARGARGARYTNGARATGTAYTAYMGNAARGGNACNGAYCARCAYYTNACNTTYYTNMGN AAYATGMGNGARGCNCAYGCNATGTAYCCNTTYACNGGNAARMGNGAYAARGARYTNTTY GAYAARGCNYTNGCNGARYTNYTNYTNMGNYTNCCNATHYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGGARAARATHAARTTYTAY AARGGNTTYATHATGTAYMGNCAYGTNYTNACNAARCAYTAYAAYAARCAR---ACNYTN AAYACNMGNGGNACNMGNGAYMGNGCNATHGTNATGGTNGAYGGNGTNCCNTTYGGNATH YTNAAYMGNGARTCNGTNATGGARGTNAGYATHATGGGNTCNAARGGNCARCAYYTNGAY ATHYTNGTNGARAAYCARGGNMGNGTNGGNTTYTCNACNGAYATGAAYTTYAAYAAYAAR GGNATHGTNGGNAAYGTNTCNYTNGGNGGNGARATHYTNACNGGNTGGGCNYTNTAYCCN YTNCAYYTNGARAAYGTNAAYGARTCNYTNATHTCNTCNYTNAARCAYMGNTCNTCNGGN YTNCARCCNGCNAARTCNGCNAARGGNTCNYTNATGACNCCNTCNYTNTAYGTNGGNACN ATHAAYCCNTCNGGNCCNGAYAARYTNCARGAYACNTAYYTNGAYCCNGGNGCNTTYAAR AARGGNCARGCNATHGTNAAYAGYTTYAAYYTNGGNMGNTAYTGGCCNYTNMGNGGNCCN CARGTNMGNYTNTAYATHCCNAARCCNGTNTTYCAYYTNCCNCCNGCNACNAAYTAYATH TAYYTNTTYGARYTNGARTAYGCNCCNTGY------------------------------ ---------------------------------------ATGACNAAYYTNGARGTNGAY CCNATHTTYGTNAARGCNYTNMGNYTNYTNCAYTCNAARGCNAARGAYAGYGGNGCNCAR YTNAARGCNATGYTNGAYGAYGCNATHGCNCARMGNAARGGNATHAARGTNCCNYTNCAR TCNGGNGAYATHGARAARGCN------------TCNMGNAAYGAYGAYGAYGGNAARAAR MGNGARGCNGARAARCAYTCNYTNGAYAARACNTAYAARGAYTCNTCNGARCCNGAYATH AARAARGCNAARYTNGAYTCNTCNAARCARAARGTNAGYAGYGARMGNGAYGCNMGNGAR AARGARAARGARMGNGARMGNATHAARAARGAYAARGAYAARAARGAYAARGARGARAAR GARGCNCARMGNCARAARGAYAARGCNGARAARGARMGNAARGARAARGAR------AGY GCNAARCARGARATGGAYATHGTNATHCCNAGYGAYGARGARGARCARGCNTCNCARATG GAYGCNGGNGAYTTYGCNYTNGARATGGGNATHGCNTGYGTNGTNTGYAARCARTTYGGN GTNAGYTCNGGNAAYCARYTNGTNGARTGYCARGARTGYMGNAGYYTNTAYCAYCARGAR TGYCAYAARCCNCCNGTNACNGGNGARGAYGTNAGYGAYCCNMGNTTYGTNTGGTAYTGY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AGYCCNGCNAARATHGTNATGGCNCCNMGNAAYAARAARGTNGCNGAR GAYGARACNGTNAGYTTYTTYTGYMGNGCNTCNGGNAAYCCNACNCCNACNATHCAYTGG GARCAYAARGGNMGNGTNGTNAAYCCNACNCAYAGYAARTTYGARGTNYTNCARMGNGGN CAYATHTCNGCNYTNMGNYTNAARCCNGTNAARGCNAAYAARAAYAAYACNTCNTTYTCN TGYGTNGCNAAYAAYGGNATH---AGYATHYTNATHGCNGGNCCNGAYATGGCNGAYAAR ACNGCNYTNGCNTTYCARGCNGCNGTNTCNGTNGCNGCNACNGGNTCNAAYGTNATHCAY ATHTGYACNCAYCCNATHTCNMGNYTNCCNATGCCNATHCAYGGNATGMGNTCNCCNGAR CCNAGYATHATGMGNAAYGTNGAYTTYYTNTAYTTYCARGARTCNAGYGARYTNATHAAR TGGYTNGCNAAYGTNCAYACNAARAARAARYTNCCNACNTAYATHATHATHGARGAYATH YTNGCNTAYGCNACNGCNATGAAYGARAAYAAYGTNGARATHAGYYTNGCNAARATHTGY GCNYTNATHTCNAAYTCNTGYCARTGGATHCARACNCAYAAYAARCARMGNNNNTGYCAY GTNYTNYTNACNGCNCCNTCNMGNATHACNTGYTTYGAYMGNGTNYTNTCNCARTTYGAY TTYAARGTNGCNCAYTAYAARGGNCCNAAYGAYGGNGAYCCNTTYTCNCAYYTNTCNTTY TCNTGGMGNACNGGNCARATGGAYATHTCNTTYCAYAARCAYAARGAYTGYYTNATGATG AARGAYGTNTCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARAGYCAYATHAGYYTN AARMGNGTNAAYAAYTGYGARGGNCCNCARACNMGNATHCCNGTNAAYACNGAYAGYCAY ACNTCNAARCAYGGNCCNCAYMGNGARGTNGARCARCARGARGCNATHGARGARMGNYTN ATGAAYATGGARACNCAYYTNMGNYTNTAYGGNAARGARGCNGAYGTNTTYAARMGNATH AARTGYYTNGARGAYMGNGTNYTNTTYYTNGARGGNATHTCNCCNGARTAYTTYACNCAY GGNATHCCN--------------------------------------------------- GTNCCNACNAARCARTGYGCNGCNGAYATHTCNGGNYTNCAYACNGARGTNGTNGTNAAY AARTTYGARGAYCAYYTNTTYATHATHGCNACNCARTAYYTNAARYTNGGNACNYTNATH CARGTNACNMGNGAYGTNATHAGYGAYGARGTNCARGGNCAYATHCCNATGTTYTCNACN MGNGTNYTNYTNGGNAARGAYGARCCNYTNACNCAYGTNATGGCNAARACNATHGTNTCN TCNYTNAAYCCNCCNATHCCNGTNATHYTNAGYYTNGCNYTNAARAGYACNTCN------ ---------------------------------------ATGGCNAGYAAYTTYCAYTTY GARGCNMGNMGNYTNCARATGCAYAARGAYMGNGTNTGYAARGTNMGNMGNGARATGGCN YTNACNGARACNCCNCARCCN------------------GTNGARGAYCARAARCCNGAR CARGTNATGTGYACNGAYCARGGNCARTTYTAYCARACNMGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TTYCAYGARGTNGARACNMGNGCNGAYATGCAYYTNTCNTCNGCNYTNGARTAY TTYYTNGAYGGNAGYYTNAGYCAYTAYAARATHATGGGNCCNGARGCNTGGGTNTCNTGG TCNACNYTNGCNAAYGAYATHAARGGNAARCARYTNACNYTNMGNMGNATHATGCCNAAR TAYTAYGARGAYGTNGARGAYAARCARGCNAARTCNAARGTNGCNTGYAGYMGNATHMGN GAYGAYYTNYTNGARTGYYTNYTNAARAGYGAYTGYGTNMGNAARGARAARAARACNCCN MGNGARTGYATG---------AAYMGNYTNTAYGAYCCNTCNGTNCCNGAYGARTGYGCN AARYTNMGNACNGCNTTYTTYGARTGYAARMGNTCNYTNYTNGAYATGMGNACNMGNTTY MGNGGNMGNAARGAYAARATHAARYTNYTNGAYGCNAARGAYACNYTNGAYGAYGCNTTY AARAARACNAGYTAYYTNTTYYTNTTYGCNACNMGNAAYYTNTGYCARAAYMGNMGNYTN YTNTCNGAYYTNCARCCNTAYYTNTCNAAYACNGARCAYAARMGNATH---GTNATHCCN GTNGAYACNCARCCNAARAARAAYMGNGGNTAYCARYTNGAYACNAAYYTNMGNAGYYTN AARGCNATHGAYTAYTGGTCNMGNGAYACNTTYTTYAAYAARAGYGTNGARMGNYTNTTY CAYTCNTCNATHGCNGARMGNYTNGARMGNGAYMGNAARYTNGARGARGARMGNCAYAAY TTYYTNGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNTTYAAYCCNGAYTTYGCNGGNYTN CCNGARGGNYTNCAYCARGTNGGNTGGAARGGNGGNGCNGARGCNCCNTGYATHATGCAR YTNYTNTGYGARMGNCAYGAYGGNYTNGTNGTNGARGCNAARACNATHAARGARCAYTGG TGGAARCCNCAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNCARGAYACNGTNGGNGCNATHTGYATGGAYGARAARGGNAAYATHGCNGCNGCN TCNTCNAGYGGNGGNATHTGGYTNAARCAYCCNGGNMGNYTNGGNCCNATHGCNATGTAY GGNACNGGNTGYTGGGCNCARAAYCARATHCCNAARTCNAARCCNGGNGTNGCNGCNGTN ACNTCNGGNTGYGGNGARCAYYTNATGCCNACNATHYTNGCNAARAGYYTNGCNGAYGGN ATHMGNTGYACNGARAAYTTYTCNCARGCNYTNCCNGAYATHTTYCARGARAAYTTYATH GARTCNGARTTYYTNGTNAAYACNTCNGARAARYTNGGNGGNGCNYTNGTNYTNAARTCN TCNCARGAYGARGARGGNCAYGARYTNGARYTNTGYTGGATHCAYTCNACNGCNAGYYTN TGYTTYGCNTTYATGACNGGNAAYCARAARTCNCCNACNACNGTNATGTCNMGNYTNGAR GAYCAYTGYGTNCARGGNCARTCNTTYACNATGGGNGGNCAYYTNTTYGTNYTNATGGAY ATGGARGARYTNAARTCNATHTAYTAYGGNYTNGAYATHGTNAAYGARCCNGTNATGAAR AAYAARGAYGCNCCNYTNGGNGCNGTNCAYGTNACNTCNAARTTYGGNCARCARTAYCAR TGYAGYTTYCCNGAYCAYGCNATGGARGARAARAARAARGARGARGARGARAARATHGCN YTNAARACNGGNATHGTNGARATGYTNAARCCNATHGGNTCNAARGARTGYYTNTCNAAR ACNAARGAYTGGTGGAGYTAYGARYTNTGYTTYGGNAARTAYGTNMGNCARTTYCAYATG GARGAYGGNGAYATHAARGGNAAYATHATHTAYYTNGGNTAYTTYGARAAYGARTTYGAY TGGGGNAAYGARACNGCNAARAGYGARMGNYTNAARAGY------ACNYTNAAYGTNTAY CAYTCNCARACNTAYACNYTNGGNACNAARTGYGAYYTNACNGGNCARATGMGNMGNGCN GARGTNMGNTTYATGTGYGARGARAAYTCNGARGAYTAYYTNTCNMGNATHGAYGARTCN GCNACNTGYGTNTAYACNGTNACNGTNATGACNTCNMGNATHTGYMGNCAYCCNTAYTTY AARCCNCCNGTNAGYMGNAARCCNATHGARATHGAYGARATHAARACNMGNTAYCARAAY TCNCARAAYAARYTNGCNAAYATHMGNMGNAARYTNTCNCARGARAAYAAYTGGGARACN GARATHGAYAARGCNATHACNGARGCNGARAGYGARTTYGGNGTNAARYTNGAYMGNACN YTNGTNTCNGGNYTNTCNGAYACNYTNAAYAARYTNGTNAAYAARYTNCARGAYACNGAR GCNGARYTNAAYTCNATGGAYACNGARATHAAYAAYYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNCAYGARTAYTAYGAYATHCCNTAYATGTAYYTNGGNATHCCNTTYGCNGCNGTNYTN GGNYTNGTNATHTTYGTNYTNGARTGGAAYTTYCCNTGGCARTCNGARGTNGAYACNGCN GAR---GCNGGNGGNATGATGGGNATGMGNGCNTGGCCNCCNTAYYTNGTNGGNGCNYTN ATHGGNTCNYTNCARATHCCNATHGTNYTNGCNAAYCAYGAYACNYTNGGNACNGCNACN AGYTAYGTNACNATHACNGCNCARATHYTNATHYTNAARCCN---------YTNMGNAAR GCNYTNGCNTAYYTNAARAAYTAYMGNTTYGGNTCNGARAAYTGGTGGCARGTNACNTTY ATGTGYAGYGGNATHYTNGGNGCNTGYGTNTCNGCNAAYGCNTCNMGNACNTTYGGNTCN GTNGCNGGNGTNACNGCNTGGCARGGNTTYTGYGGNGGNTTYTTYATGATHTAYGGNTCN MGNYTNGCNGCNGGNTGYACNAGYGGNCAYGGNYTNTCNGGNACNGGNYTNTTYGCNCCN YTNTCNATHGTNGCNGTNGCNTCNATGTTYGGNGCNGGNATHTGYGCNAGYTTYYTNATG MGNTTY------------------ATGMGNGARAAYATGGAYAARGTNAARTGGGARYTN GARGGNGTNAARACNGCNGCNGCNGTNTCNGARGAYAAYAARCARGARGAYATHACNACN ATHMGNCAYAAYTAYCARCARGARGTNGCNAGYYTNCARCARYTNYTNCARGARGCNTCN GARACNGCNTCNGAYAAYACNGCNGCNCARTTYGARTCNGARMGNAAYAARYTNGTNTCN YTNAAYGARAAYTAYGARGARGARATHCARGAYYTNMGNAAYAARYTNAGYCARGARMGN GARGGNTTYYTNTCNACNGTNGCNAARTCNATHAARMGNGTNGGNGCNGTNGGNTCNGCN AAYACN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AAYAGYACNGGN CAYATHACNCCNACNAGYATGAAYCCNGGNTTYCCNATGGGNATGCARCAR--------- ------CCNCARCARCARCARCAYTCNCCNAAYAGYYTNGCNGCNATHGGNCCNMGNAGY GTNYTNGGNGTNCARAGYCARGCNGGNCARCARAGYYTNGCNAAYYTNCARAARMGNCCN TTYAGYGCNGCNGGNCCNATGCARAAYTTYGCNTCNAAYTAYGGNTTYGGNGGNACNMGN TCNATHGAYTCNCAYCCNACNATHGAYYTNTCNGAYTTYCCNACNYTNAGYAGYMGNTCN TCNGCNACNCCNAAYCCNATGCCNTCNACNMGNAAYTAYGTNGGNATGGTNAGYAARCCN GCNCARGAYAGYGCNCCNGARTTYAAYATHTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AGYMGNGAYGAYATGTCNCCNCCNMGNAARCCNATGTCN MGNAGYTAYGAYAGYTCNGAYMGNGGNMGN---------------AARCAY---GAYMGN TAYGARGAYAGYTAYGAYMGNGGN---CCNCARTCNMGNTCNMGNGAYYTNTAYTCNTCN CCNTCNMGNGAYTCNGGNMGNAAYTTYGAYMGNYTNTCNCCNCCNMGNAGYAGYYTNMGN GAYMGNGARTAYCCNTCN---AGYTCNMGNGAYTTYATHAGYTCNAARGGNGAYTAYYTN TCNGCNMGNAGYTAYACNCCNCCNMGNGAYTCNGGNTAYAGYTCNTCNTAYAARGAYTCN TAYAGYAAYGCNCCNMGNGARGAYMGNCCN---ATGMGNGARTAYCCNTCNTCNMGNGGN MGNTCNGAYTAYGARMGN------------TCNMGNGAYTTYMGNGAYTCNCCNMGN--- GAYTAYGGN---TCNTCNMGNGAYTAYCCNCCN---TCN---MGNGGNAGYGGNTTYMGN GARCCNYTNGGNAGYAARGARTTYMGNGGNTCNTCNMGNAGYGARMGNTCNTAYAGY--- ------------------------------------------------------------ ---------------GGNMGNGGNMGNGGNTCNMGNTTYGAYGAYMGNGGNCCNTCNMGN GAYTTYGTNGGNTCNMGNGGNMGNGGNGGNCCNCCNMGNGGNMGNGGNMGNCCN---GAR TTYTCNGGNAGYMGNAGYGGNGGNGGNAARMGNCCNMGNYTN------GAYAGYGGNGAY GGN---------TAYMGNMGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AGYYTNGAYATGTCNGCNTGYAARYTNCARCAYATHTTYACNMGNATG GGNGTNGCNYTNAARTCNYTNYTNTGYGCNACNMGNGCNACNCCNGCNTAYAARYTNNNN AARAAYCARGGNGARAARGGNGGNGGNTAYATHYTNAARTAYMGNYTNTAYYTNGGNAAR CCNCARACNCAYMGNYTNGGNGAYGGNTTYAARATHGTNMGNGCNGGNGCNYTNCCNACN GCNTTYGGNYTNYTNAGYATHAAYGTNGCNTAYMGNACNAARYTNYTNYTNTCNCCNGAR ATGACNTCNTCNGCNTCNTCNTCNATGGARYTNACNGAYAAYTAYTTYATGAARGARTGY GGNACNMGNACNMGNCCNTCNCCNCCNTCNGCNCCNCARCCNTGY--------------- ---TCNCCNMGNATGMGNAARYTNTCNACNTCNTCNAGYCAYGARAAYCARTCNGGNAGY CCNTAYTGYTTYGCNGTNTCNGTNTCNCCNMGNGCNCCNGARGAYGTNCCNYTNTGYTCN ATHCCNTCNAARGARAAYGAY------YTNTGGCCNYTNTCNAGYATHYTNAAYACNGAY GAYYTNCCNGARCCNGCNATHGGNGCNTTY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------MGNGCNCCNGGNTGYMGNATHATGTTYTGYMGNGARTCNTTYTAY CAYGCNGAYATHGAYGAYYTNGAYATHMGNATGGAYCAYATGYTNCCNACNTTYAARCAR MGNCCNAARGGNAARAARAGYAARCARYTNAAYMGNAARGAYTCNCARCARGAYTCNGAY AGYATGGARGARYTNTTYGCNAAYATHACNCCNTCNATHTCNACNTCNTCNMGNCCNMGN MGNTCNACNGAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGGAYTAYYTNYTNCAYATGYTNYTNYTN ATGAARTGGCAY---CCNCARGGNGAYTGYGCNTAYYTNATGGARGGNGCNMGNACNATG AARGCNCCNAARTCNTTYGTNGGNTGGYTNAGYGARMGNTGGYTNAGYGCNTAYGARTAY TTYCCNCARGAYAARAGYTTYAARGGNAARMGNGTNAGYGARTGYYTNYTNGAYYTNGAY ACNCARGCNGTNGARTCNYTNATHGAYGTNTTYTCNAAYYTNAAYTCNAGYAGYAAYGAR GAYGCNGTNGTNAAYCARACNTCNTCNGGNGAYGCNYTNTTYGTNGTNGAYATGAARGGN CCNGCNGAYTTYTCNTCNTTYAARGARAAYAARTCNTCNACNGAYATHCCNAAYATHTCN TGYATHATHCAYAAYGTNAGYGGNCARCCNCCNGTNCCNAGYMGNCCNMGNAAYATHTCN CCNACNGAYTCNTCNCCNGCNTCNAAYAGYCCNGGNGARCARMGNMGNCAYGTNAARGTN ATHAAYATGCCNCCNGGNTCNTCNTCNGGNGGNTCNGTNTCNCCNGCNGGNAARGCNGCN AAYTCNMGNCAYTTYMGNATGCAYTTYGGNGAYACNGGNGGNATHTGYACNGTNCARTCN TCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARCAYCCNCCNGGNCAR GARAAYGGNAAYTGGGCNATGTTYGARGAYGARGARAGYCAYATGYTNATHGGNTCNGGN GTNAARCARCAYTAYAAYAGYYTNGARCCNCCNAAYTTYGAYTCNTCNTCNATHTCNTCN GARGCNGARAGYATHGAYGAYGTNTGGACNATHACNGAYGARCARMGNGARTAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR AARGAYGTNGTNMGNAARTGYATGAARMGNAARACNATHMGNAARACNAAYGAYGGNTGY MGNYTNATHGAYGARTCNTTYACNGAYAGYGARACNGGNATHTAYGARATHTAYGARAAR ATHAARAAYYTNGCNATGMGNGARTGYGARTGYGGNAARACNMGNCCNAARTCNGGNGAY GTNGARCCNCCNTAYMGNATHACNGGNAARGTNAAYAARAAYCCNTCNGTNYTNAARAAY AARGARCCNCCNCAYACNMGNAAYYTNGTNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNYTNAARCARCARYTNACNGTNTTYAARGARGAYTTYGAYMGNGARMGNAAY GAYMGNGTNGCNATHAARGGNCARYTNATHAARGCNMGNACNGARAARGARCARATGAAR ATGTCNYTNACNACNAARATHAARTTYGCNAAYACNAAYYTNAARAARCAYGARGARGAY YTNYTNAARAARTCNMGNCARGTNACNGAYYTNCARGGNCARAAYGAYGARYTNAARGCN AARYTNCAY--------------------------------------------------- ------------------------------------------------------TCNTCN TCNGTNYTNATGYTNNNNNNNGARNNNAARCARMGNMGNMGNMGNGGNTGYTGYTTYTGY YTNYTNCCNYTNYTNYTNYTNYTNCCNYTNGCNYTNYTNGCNGGNCAYTAYTCNGGNCCN AARAGYYTNAGYTCNATHCARGTNGARGCNATHGTNMGNGCNATGYTNGCNAARGARATH GAYTCNACNAARGARATGATHAAYGGNGARGTNAAYTCNYTNGCNGGNYTNCAYATGCAR GAYGTNTCNTCNYTNAARCARAARYTNAARAAYYTNGARGARATGATHCARTCNACNAAR GAYACNCAYATHGTNGCNGGNGARYTNCAYGCNGCNAARGAYTCNTTYCAYAGYATGAAY GARAARCARMGNACNGARTGGYTNACNGTNGCNGARGCNCARGARACNAARTGYYTNGAY ATGMGNAAYGARGTNAAYGGNYTNGCNAAYCARAAYGCNGCNYTNGCNGCNYTNYTNMGN TCNTGYTGYCARAAYAAYTCNATGYTN---GCNAAYGTNMGNGCNCARYTNATGACNYTN YTNTCNCARATGACNTTYGARGAYGGNGAY---TCNTTYGGNAAYYTNATGGCNTTYATH GGNGARCAYTAYGTNCAYMGNAAYGARYTNGAYAARAARYTNTCNGCNGTNGCNAARGAR GTNGCNGARAARATGMGNATHGCNYTNGCNMGNCAR------GCNGARGARAAYCARGCN GTNYTNTCNMGNGGNYTNGAYGARYTNACNGTNAARGCNATHGTNGARGARTCNYTNACN CARTTYAGYGCNGAYMGNGTNGGNATHCCNGAYTTYGCNYTNGARTCNGCNGGNGGNAGY GTNYTNAAYATHMGNTGYTCNGARACNTAYTAYMGNAARACNGCNYTNGTNAGYGTNTTY GGNATHCCNYTNTGGTAYATGTCNAAYTCNCCNMGNACNGTNATHCARCCNAGYGTNCAY CCNGGNGARTGYTGGGCNTTYAARGGNAGYTCNGGNTTYYTNGTNGTNCARYTNTCNCAR CCNGTNCARCCNACNGGNTTYACNYTNGARCAYATHCCNMGNGCNYTNGCNCCNATGGGN AAYATHGAYAGYGCNCCNCARGCNTTYGCNGTNTTYGGNYTNACNGCNGARGAYGAYAAY AARGGNATHACNYTNGGNAAYTAYACNTAYCARGAYAGYGGNAARCCNATHCARCAYTTY CCNATHCARAAYMGNCAYCCNGGNGTNTTYCARTTYGTNGARYTNMGNATHYTNACNAAY CAYGGNAAYCCNGARTAYACNTGYGTNTAYMGNTTYMGNGTNCAYGGNYTN--------- ---GAYTAYAARTGYCCNTCNTGGYTNAGYGAYMGNYTNACNCARYTNGTNATHYTNGAY AARGTNAAYACNMGNAARTCNTAYGAYTGYCCNYTNTCNTCNTCNYTNATHACNTCNATH ATHGGNCCNAAYACNCARGTN------GCNGARATHAARGARCCNYTNCARACNAGY--- ---MGNCCNTCNCCNGCNAARGARGCNAARGARATHATGMGNATHMGNCAYAARAARATG AARAARCAYAARYTNMGNAARYTNMGNAARMGNATGTAYTTYYTNTGGMGNAARCARAAR ATGACNMGNAARGCNAARMGNGAYGCNATHTAYTGGAARGARATHGCNGARATHAARAAR YTNGGNGARGARTTYAAYCCNGARGAYTAYGTNAARGARCARYTNCARAARGCNMGNAAR GGNGGNTTYTAYYTNAARGTNATHCAR--------------------------------- ------------------------------------------------------------ ------------------TTYTGGATHGGNGGNACNGAYGARGGNTCNGARGGNAARTGG CAYTGGGCNCAYTCNGGNAARCCNGTNACNYTNTCNMGNTGGCAYCCNGAYGARCCNAAY AAYGCNGGNAARAAYGARCAYTGY------ATGCARGGNYTNGTNGGNGAYCARAARTGG AAYGAYAAYGTNTGYTCNGTNMGNGCNGGNTAYATHTGYGARMGNYTNATHCAYTCNGTN YTNATGTGYTTYAARTCNAARCCNCAYYTNYTNGAYTCNGGNGARGCNGTNGAYYTNATG AARYTNATGYTNTCNAARGAYTGYGAYGTNAAYGTNAARGAYTTYTCNCAYAARTCNCCN YTNATGATGGTNGCNGARYTNGCNGAYCCNMGNATHATGAGYATHATHYTNCCNAARTGY YTNGAYTGGCARYTNACNAGYCCNYTNCAYATGTCNTGYATGAARMGNTAYAGYAARAGY ATHTTYAGYGGNGGNTGGAAYCARTCNTTYYTNGCNYTNTAYMGNGAYTCNAGYYTNAAY GTNTAYAARMGNCARGGNGAYTCNACNGCNCARGGNTCNATHTTYATGAARAAYGTNTGY AARTCNTTYGCNTAYGGNGARTAYACNAAYGGNATGCCNGAYMGNCCNGAYYTNCCNGGN GGNGTNTCNATHGAYTGYYTNATGGGNATHCCNCARAARCCNAGYAGYAARGCNAARATH CAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYGCNACNTAYYTNGGNAARATHGARATGAAYACNGTNACN GGNYTNCARAARGAYYTNATHAGYAARCAYTCNTCNAARYTNAGYYTNTAYTAYGGNTCN TGYGAYCAYTGGGCNCCNATGAAYTAYTAYTAYGARYTNATGTCNGARTTYCCNGAYATH GAYGCNAARYTNTGYTGYYTNAAYYTNMGNCAYGCNTTYATHYTNGARCARACNAARGGN MGNGARATGGCNMGNYTNGTNCARCARTGGACNCARGTNCAYCAYMGNAARCAYGGNTAY TCNAGYYTNACNATGGAYCAYAGYAAYTGYMGNYTNTTYGCNAGYTGYACNGAYGAYTCN YTNTAYGARTAYAAYYTNATGTCNTAYMGNGAYAARCCNGTNTGYACNTTYMGNGGNCAY AARAAYTCNTCNTTYTAYGTNAARACNGCNGTNAGYCCNTAYATHTGGCARATHGAYAAR CCNGARTCNCCNCCNGTNYTNYTNAARGCNCAYGAYGCNGARGTNACNGGNGTNGCNTGG TGYCCNCAYAAYTTYACNCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGNTGYGAYYTNGTNGTNGAYGTNGGNTCNGGNYTN GGNTAYYTNGAYCAYGTNYTNCAYCARGTNTAYGGNCAYMGNGTNYTNGGNYTNGARACN TCNCARAGYCAYGCNTCNGCNGCNGARMGNMGNGCNGTNAARCARGGNATHAAYTGYGGN GGNGTNAARAGYGTNCARTTYAAYATHGARGAYAGYCAYGAYTGYCAYGARACNTTYCAR TTYYTNATHCAYGAYGTNGTNAARGCNYTNTGYTGYGTNTGYTGYTGYTAYCAYAARATG GCNTTY------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNCARGGNAARTTYTCNAARTTYCCNYTN AGYATGYTNGGNMGNGCNATHCAYGARCARCAYCARAARGAYTGYAGYAGYGCNTTYGTN ACNCCNTTYACNATGMGNYTNGGNGCNCARGARACNMGNTGYMGNTGGCARCARCARACN GARACNGAYCAYGCNTCNCAYATHMGN--------------------------------- NNNGARGAYAGYGCNAGYACNMGNCAYMGNATHAARAARTGYGAYTTYTAYAAYTTYGAY ACNTTYYTNACNTCNTAYTAYAGY------------------------------------ ------------------------------------------NNNYTNTGYCARATHYTN CARGTNYTNCARGTNGTNATGCARCCNYTNATHGARAGYYTNYTNTAYCARGAYMGNYTN CAYTGGTTYMGNGARAAYGGNCAYCCNTCNGCNCARGTNGTNGCNYTNTTYGAYGARGCN GTNTCNCCNMGNAAYYTNGCNYTNGTNGCNAAYAARACN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GCNYTNYTNTCNGCNTCNGTNTTYCARTGGGARAAR GARMGNGTNACNAARGARGARATHGARGGNTGYYTNAARGARATGGAYGARGTNCARCAR YTNGTNGCNYTNAGY------MGNATHCCNAARACNGTNCARYTNACN------------ ---------------------------ACNAARYTNGARGARTGGGARCARYTNGTNGAY AARGAYCAYTTYAARGTNTGGMGNMGNTTYGTNCCNGARTCNGARYTNTAYGARTAYMGN GTNTTYGGNCAYTTYACNGAYATHCCNCCNMGNGCNTTYTAYAAYACNCARGTNGAYGTN GGNTAYTGGAARGAYTGGGAYCARCARACNATGGAYGTNMGNATHGTNGAYAARGAYGGN GAYTCNGGNTCNGARGTNATHCAYTGGGTNTAYAARTTYCCNTAYCCNATGTTYCCNMGN GAYTAYGTNTAYGTNMGNMGNCAYACNYTNGAYCCNGAYTCNAAYACNATGATHATHACN GCNMGNGCNACNGARCAYCCNAAYTGYCCNAARGAYGCNTCNTAYGTNMGNGTNGCNACN TAYACNTCNMGNATGGTNATHATHCCNTAYACNGCNATHGAYGARAAYGGNTTYACNTAY GTNATGACNTAYTGYGAYGAYCCNCARACNAAYTTYCCNACNGTNTGYTAYAARTGGATG GCNAGYACNGGNGTNCAYGARTTYYTNGARMGNGTNCAYAARGCNGCNTCNAARAARCAY GARAARAGYTGY---GAYGTNAAYTCNGCNMGNATGGAYGAYAGY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYYTN AAYGCNYTNGARTCNYTNCCNGAYGTNGCNACNACNGAYGARGCNAARMGNYTNGTNGGN GTNYTNCCNTAYGARGAYGGNCARGARGARCCNGAYTTYMGNCCNCARTGGGAYAARGAR AARTGGAGYGCNTTYATGGARGARTCNAAR------------------------------ ---------CCNTTYGARATHGARGARGAYGARATHAARGARGARGAYGAYYTNTTYTCN GAYGCNAARGARAARCCNTCNTCNCCNGARACNGCNAGYCCN---GARTCNGTNGTNAAY GGNTCNGAYAGYAAYCCNTTY---GGNGAYAAYGARAARGARGAYGAYYTNYTNAARGGN GGNAGYTCNGARATHAARYTNGAYTCNGAYGARGAYGCNGGNGCN------------GAR GARGARGARAARGARTCNMGNAARAARCCNGARGCNTCNGCNGCNGCNGCNCCNMGN--- ------------------------GARATHACNCCNGARATHTCNGTNTCNGARGTNATH ATHACNAARACNAARGTNGCNGCNCCNTCNYTNAARGCNGAYGAYTTYAAYGARAGYTCN GAYGARGARAARGARAARTAYGARYTNGARATHAARATHTCNGARACNYTNAARATGGGN GAYGGNATGTCNGCNTAYATHGTNTAYAARATHGTNACNAARACNACNAAYCCNGCNTTY MGNAARCCNGARAGYGTNGTNCARMGNMGNTTYAGYGAYTTYYTNGGNYTNCAYGCNAAR YTNGCNGARAARCAYGTNCCNTTYGGNATHATHGTNCCNCCNGCNCCNGARAARAGYGTN ATGGGNATGACNAARGTNAARATGTCNAARGARGAYTCNGGNTCNACNGAYTTYATHGAR AARMGNMGNGCNGCNYTNGARMGNTAYYTNATHMGNACNTCNYTNCAYCCNGTNYTNGTN AGYGAYAGYGAYTTYATHGARTTYYTNGARAARGAYGGNGAYYTNCCNAARGCNACNAGY ACNTCNGCNYTNAGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNCAYGAYGARCAYMGNGAYGAYGAYGAYAAYACNAGYTAYAAYAGYAGYGAYGAY GTNYTNAAYACNYTNMGNCAYCARCARMGNGGNCCNYTNGARATGTCNGCNMGNMGNGCN MGNYTNACNTCNTTYAAYGCNMGNATHCAYAARAARAARMGNATGMGNGCNACNYTNMGN ATHACNCARYTNCCNCCNTCNATHAGYGAYGAYGARYTNTCNTCNGGNAGYGAYMGNMGN TAYGARGARCCNAARYTNMGNGAYCCNAGYGAYCARGAYGAYATGGGNGARGCNAAYTCN AARAARGGNAARMGNGTNTTYTTYTTYMGNAAYGGNGAYATGCAYTAYAARGCNAARCAR ATHYTNATHAGYAGYMGNACNTAYCARAAYTTYGARAARYTNYTNACNGAYYTNAGYTCN ATHATGGARACNCCNTCNGGNGTNAARTTYATHTTYTCNTGGTCNGAYGGNMGNGARATH AARAAYATHTCNAGYTTYGARACNGGNAARTAYTAYATHTGYTCNAGYATHAARGAYYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TCNACNATGGAYCARGAYGCN---GAY ACNTCNGGNCCNCCNGTNAAYGGNGARGGNGAYGGNCAYAARGARATHYTNGCNCCNTCN GARGGNCCNMGNGARGARYTNATHCARACNGCNGTNAARTTYYTNCARAAYCCNMGNATH ATGACNAGYCCNYTNCAYCARAARAARACNTTYYTNGARMGNAARGGNYTNACNAARGAY GARATHGAYATHGCNGTNCARMGNTCNGGNGTNACNGAR------ACNACNGCNCARTCN GGNACNAAYAGYTCNTAYCCNGTNCAYCCNACNCAYCCNGAYCARGTNGTNATGCCNTCN CCNTAYGGNCCNYTNCCNGTN---GTNCCNGTNCAYCCNCARTCNMGNTGGGCNCARATH MGNAAYYTNGCNTTYACNTCNGTNGTNGTNGCNGGNGTNTCNTAYGCNGTNTAYCARYTN TTYCARATHTAYYTNMGNCCNYTNATHYTNGGNAARTCNGCNCARGTNAARMGNYTNGAR AARYTNGARAGYCARGTNGARGARATHAAYAARTCNGTNACNGARTCNYTNGCNTCNATH GGNACNACN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TTYATHAARGARGTNYTNGCNGGNACNACNTCNGAY TAYYTNTTYGAYTGGAGYYTNCCNYTNCAYTGYCCNGARYTNGCNAARGARTTYTCNYTN CCNCCNTAYTTYAARGAYAAYTTYYTNYTNCARACNTCNCCNGGNTCNYTNTAYMGNGAY AGYTGGCCNAGYYTNTTYATHGCNCCNAARGAYGCNGTNAGYAGYYTNCAYATHGAYGCN TTYGCNTCNCAYTTYTGGATGGCNYTNTTYCARGGNGARAARMGNTGGACNTTYTTYGAY CCNCARGARACNTTYYTNYTNTAYCCNTGGTAYTTYAAYTCNYTNGAYCCNATHTTYGAY GTNGAYATHAGYCARTCNGAYYTNGGNAARCAYCCNYTNTAYGCNYTNACNCAYCCNCAR CARTGYACNYTNCARCCNGGNGARYTNYTNTTYGTNCCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARYTNYTNAARTGGAARATGAGYCCNATHACNCCNATHGTNGTNAAR GCNACNYTNGCNMGNGTNGGNTTYMGNATHACNAARMGNAAYCAYGAYTGGYTNGGNTGY TTYGGNAARCAYATGMGNGCNACNTGYTTYMGNCCNYTNMGNGARTAYCARAARYTNAAY CAYTTYCCNGGNTCNTTYCAYATHGGNMGNAARGAYAARYTNYTNAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGNGTNGARTAYGTNAGYGARCCNMGNTAYCARCAY GARGCNTAYGAYGTNAARGTNGAYGCNGGNGTNTTYGARAAYCARCCNTAYGARGAYGGN GAYGTNGTNAARGCNGARACNCARGTNGARGARTAYGTNCCNGARMGNGGNTTYACNAAR AAYGTNGCNGCNAARTTYAARGARYTNGARAGYACNGCNAARTCNCCNCCNYTNTCNCCN GGNMGNMGNAARGARTTYACNCCNCCNMGNGAYGAYGCNGGNAAYMGNCAYGCNGGNGTN TGYGARAGYACNCCNCARTTYAAYCCNGARGTNGTNACNTCNGARGARATGCCNGARGAR GTNYTNCCNGARMGNGGNATGGCNAARAAYYTNGCNCARMGNTTYCAYMGNATHGARGCN GARAGYMGNTCNCCNGAYACNTCNAARCCNAARAARGARTTYACNCCNCCNCCNCARGAY AGYGGNGTNTAYGARAAYAARCCNGAYCARTTYCAYGCNGAYTAYAAYMGNCCNGCNGAR TCNGGNATHYTNGARAAYAARCCN---ATGGARCAYGARGAYGTNGCNAARGCNCAYGAY GGNCCNATGGAYACNGARGARYTNCCNGANTGYGGNTCNGCNMGNAAYYTNYTNAGYMGN TGGAARCARATGGARTCNAARAGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNTTYGTNATGGGNGGNGCNYTNGTNYTNGAR TCNATGGCNYTNYTNCAYTGGTGYGARMGNGARGGNTGGGGNCCNYTNGGNATHTCNGGN ATHTCNATGGGNGGNCAYATGGCNTCNYTNGCNGCNACNAAYTGGACNAARCCNATHTCN YTNATHCCNTGYYTNTCNTGGAGYACNGCNTCNCARGTNTTYACNCARGGNGTNATGAGY GARGCNATHCCNTGGGARACNYTNCARGARCARTTYTTYGARAAYATHGTNTAYCARGAR GARATHAGYAARYTNGTNATHTCNCCNGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGAAYMGNAAYGTNAARGCNCARYTNGTNMGNGCNTCNAARACNYTNACN CARCARGARGGNGCNTTYTGYAARTAYACNCAYMGNGTNTGYATGCARAAYTGYYTNGAY GGNTAYGAYTAYTGYATHMGNCAYATHYTNGARGAYAARAGYGCNCCNTTYMGNCARTGY TCNTAYATHACNAARTCNGGNAARAARTGYCCNAAYGCNGCNCCNAARCARGARMGNAAR GAYGGNTTYTGYGCNGARCAYTCNMGNAARGGNYTNATHTCNMGNCARMGNTCNTCNMGN AARMGNMGNCCNAARGARACNGCNGAYTCNYTNYTNGARGAYYTNGTNGCNAGY---TCN MGNACNGCNGCNATHCARAAYGTNGARCAYMGNMGNGGNAARGTNCAYAGYGAYAGYATH GCNAAYAARGCNYTNGAYTAYGCNAGYTCNAGYGARTCNGARTCNGARTCNYTNYTNGTN GARCAYGCNTGGMGNGAYAAYTGYGAYAGYGAYGCNGARAGYATHGAYAGYGAYCARGAR GAYATGYTNAARTAYGCNGGNATHTAYACNACNGARGARGTNGCNCARATHYTNMGNGAY AARYTNATHMGNYTNCARGCNYTNTAYATHGAYCARTTYAARMGNYTNAARCAYGTNYTN YTNACNAARMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYMGN GAYAAYATGGGNAGYGCNYTNAARGCNGCNAARATGGAYAARCARAARGCNGTNGCNGGN TTYGARGTNAARAGYAAYGARATHGCNAAYTTYCAYAARGARYTNGARAARATGAARGAR GCNATHTCNTCNAGYGAYTAYMGNATHAARTGGTTYCARAAYAARYTNAARGARGARYTN GARACNCAYAARGARACNAARGCNACNYTNGARAARACNGCNGCNAARYTNAARGARGCN AARGARGARACNGARATHATHMGNAARGARTGYCAYGCNATHGTNAARACNTAYCARGAR TCNGARGARATHAARTCNAAYAGYYTNGAYAARGARYTNAARATHAARGARYTNCARYTN AARCAYCARATGCARGARTCNAAYGAYACNGARGARATHCAYCARMGNACNAARAARGAR YTNGAYGCNYTNACNYTNCARCAYAARGAYTCNYTNGAYCARGTNAARACNYTNAARCAR AARGTNCARACNTTYGARGARACNYTNTCNGCNAARAAYTTYATGATHGARAARTCNCAR GARATHATGAAYMGNCARAARAARAAYATHACNGARYTNTGYCARAARGTNAARTCNYTN GARACNTTYGARGARGAYTAYTCNMGNGCNCARGARATGATHAARACNYTNGAYAARGAY ATHTCNGARTTYAARATHAAYAAYMGNGAYYTNCARAARGAYATGGAYTCNTGYMGNGAR MGNGARTCNAARATGYTNGCNYTNCARTCNGARYTNAGYMGNACNAAYGCNYTNYTNMGN TCNGARAAYACNAAYYTNAGYAAYAARGCNTCNAAYYTNACNGGNGTNGCNGARMGNYTN AARATGGARGTNCARGARYTNGARACNAAYGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYATHYTNCAYAAYGARGAYCAYACNYTNGGN AAYTCNYTNAARTAYATHYTNAAYAARAGYCCNGAYGTNYTNTTYGTNGGNTAYAGYATH ACNCAYCCNTCNGARGAYAARATHAAYYTNMGNATHCARACNACNGGNAARCCNGCNATH GAYGTNYTNAARCARGGNYTNAARGAYYTNAARGARYTNTGYGCNCAYATGYTNACNACN TTYGARTCNTCNACNAARTAYTAYAARGARAAYCAYYTNGAY---GAYGGNCCNATGGAY CAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GCNGARGARGGNATHAAY AARCARYTNCCNGARTAYACNAAYGTNATHGARTCNYTNGARGAYGGNAARMGNAARACN CCNGCNCARAGYAAYATGAARACNYTNGCNAARGCNCARGARGAYYTNGCNGAYGTNYTN GCNCAYCAYGTNACNTAYATHCARCARYTNAARTCNYTNAARCCNTCNTCNGARACNACN ATGGCNAGYTAYAAYAARTTYCAYAAYAAYTGYATGMGNGAYTCNATHYTNYTNACNYTN GCNTGYGARGGNACNAGYGTNTTYGGNGGNTTYGCNATHTTYTCNGTNYTNGGNCAYATG GCNAARACNGCNGAYGTNCCNATHGARTCNTTYAAYMGNTCNGGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNYTNGCNATGTGGGAYYTNGARCAYTGYGAYCCNAARAAR TGYACNGGNMGNAARYTNAGYMGNYTNGGNTAYGTNMGNACNYTNMGNYTNAAYCARMGN TTYGGNGGNYTNATHYTNTCNCCNGTNGGNTCNAARTGYGTNTCNCCNAGYGAYMGNTCN GTNGTNGARGARAAYGGNATGGCNGTNGTNGAYTGYAGYTGGGCNAARYTNCARGARACN CCNTTYGCNMGNATGAARGGNGAYCARCCNMGNYTNYTNCCNTAYYTNATHGCNGCNAAY CCNATHAAYTAYGGNMGNCCNTGYAARYTNTCNTGYGTNGARGCNTTYGCNGCNACNYTN TAYATHACNGGNTTYCAYGARGARGCNGAYGARYTNYTNTCNAARTTYAARTGGGGNGCN AGYTTYTAYAGYYTNAAYCARGARYTNYTNGARACNTAYAGYCARTGYCARACNAGY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TGGTTYYTNCCNCARTCNYTNTCNGAYYTNYTNCAYYTNAARTCN GARTAYCCNACNGCNMGNYTNGTNTGYGGNAAYACNGARATHGGNGTNGARACNMGNTTY AARAAYAARACNTAYCCNATHYTNATHTCNTCNGCNAAYATHTCNGARYTNTCNTCNGTN AARATHACNGARGAYGGNGTNYTNGTNGGNGCNTCNGTNACNYTNTCNCARATGAAYGAY GARYTNAARAARYTNATHCARAAYYTNTCNGARTAYAARACNMGNTCNYTNGCNGCNATH GTNGARATGYTNAARTGGTTYGCNAGYAAYCARATHMGNAAYGTNGCNTCNYTNAGYGGN AAYATHATGACNGCNAGYCCNATHTCNGAYYTNAAYCCNYTNYTNGTNGCNGCNGGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TCNGCNACNTCNTCN MGNYTNTCNTGYGCNGARGAYATGCCNMGNCCNAGYGAYMGNGCNGAYTCNGTNCCNAAY GCNTCNMGNYTNTGGCAYCARTCNGCNGARGGNATGYTNCARACNCCNTCNCCNAGYGAY AGYGGNGTNGGNGARYTNGARGCNATHYTNMGNGARAARGAYGCNGARATHAAYACNYTN MGNGARGTNATGGAYMGNAAYGARMGNGCNATHYTNCARGTNTAYGARGARMGNAARAAY GCNTGGGCNCARGAYGCNCAYGARYTNMGNGAYGAYTAYGARMGNCARYTNAARGTNCAR AGYMGNAARTCNTAYAARACNGARCARGTNYTNTCNYTNCAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ACNYTNGTN GCNGCNGGNYTNYTNAAYYTNGGNGAYYTNTGYYTNATGTAYTTYTGGACNCCNAAYCCN GAYGCNYTNTAYGTNTAYTAYATHATGGCNGGNGTNTGGGGNATHGCNYTNTCNGTNTGG YTNACNCARYTNAGYGCNYTNTAYGCNGARGTNTTYAARGAYAARCAYCARGARGGNTTY TCNAAYCAYMGNATGYTNGARTGYATHGGNTTYGCNATHGGNTTYTCNTGGGARCAYTTY GTNTGYATGAARATHAARATHTAYGTNACNGGNGGNATGATGGTNTTYGGNATHATHGGN TAYATHGCNGTNGARGTNYTNYTNMGNMGNGAYMGNAAR--------------------- ------------------------------YTNGCNTTYAAYACNAAYYTNMGNGAYAAY CCNAGYAAYACNGTNATHATHACNAAYGGNGGNMGNTAYGARGTNAAYGTNGGNAAYMGN GTNMGNACNTCNGTNTTYTGGGAYCARTCNCCNTCNCCNGTNAARMGNTGYTCNTGGTTY TTYAARMGNGARAARGAYAAYMGNTAYATHCCNTAYGAYGARAGYTTYGCNTCNCARYTN GARGAYGARTAYAARAARGCNATGGARACNGGNGGNTGGCAYMGNMGNYTNGARTTYCCN GGNAARGARATHATHGTNATGCAYAAYGCNAAYGTNATHGTNCARTTYCCNGCNTCNTCN GCNCCNGAYGARTGGGGNAAYGTN---GGNGAYCARATGMGNCCNGGNGTNGTNAARMGN GGNGTNGAYGAYTTYGCNACNATHGARTAYGGNGARMGNGAYGARGTNGAYCAYYTNGTN TTYTTYATHCCNGGNATHGARGAYTTYTCNGARGGNAAYGGNAARTCNGTNGARGARTAY GTNGAYGAYTTYMGNAGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNGGNATHACNGAYGARGARATHATHMGNYTNMGNCCNCARGARAARMGN AARATHGAYTTYACNGAYAARYTNTAYYTNGCNCCNYTNACNACNGTNGGNAAYYTNCCN TTYMGNMGNATHTGYAARGGNYTNGGNGCNGAYATHACNTGYGGNGARATGGCNYTNGAY TCNCARYTNYTNAARGGNAARACNTGYGARTGGTCNYTNATHAARMGNCAYCCNTGYGAR GAYATHTTYGGNGTNCARGTNTGYGGNGCNAAYCCNGAYATGATGGCNAARTGYGCNCAR GTNYTNACNGARACNTGYGAYGTNGAYTTYATHGAYATHAAYTGYGGNTGYCCNATHGAY YTNATHTTYAARMGNGGNTCNGGNAGYGCNYTNYTNGGNAARGCNACNAARYTNGARAAY ATHTGYAARAGYATGATHGAYGTNATGGGNGAYACNCCNYTNACNGTNAARGTNMGNACN GGNGTNTAYGAYCAYAARAAYGTNGCNCAYAAYYTNATHCCNMGNYTNMGNGAYGCNGGN GTNTCNYTNGTNACNATHCAYGGNMGNTCNMGNGARCARMGNTAYACNMGNCARGCNAAY TGGGAYTAYATHTCNCARGTNGCNACNGCNGGNAGYCCNATGCCNGTNTTYGGNAAYGGN GAYATHYTNTCNTAYGARGARGCNAAYYTNCAYYTNAARGARACNGGNGTNTCNGGNGTN ATGATHGCNMGNGGNGCNYTNATHAARCCNTGGATHTTYACNGARATHAARGARCARGGN CAYTGGGAYATHTCNTCNAAYGARMGNTTYGAYATHYTNAARAAYTAYACNAAYTAYGGN YTNGARCAYTGGGGNTCNGAYCAYCARGGNGTNGARAAYACNMGNMGNTTYATGYTNGAR TGGYTNTCNTTYYTNCAYMGNTAYATHCCNGTNGGNGTNATGGARCARYTNCCNCARAAR YTNAAYGARMGNCCNCCNTAYTAYCARGGNMGNAAYGAYYTNGARACNYTNATGGCNAGY GCNAAYTGYGCNGAYTGGATHAARATHAGYGARATGYTNYTNGGNCCNGTNCCNCCNAAY TTYYTNTTYYTNCCNAARCAYAARGCNAAYGCNTAYCARATGAGYTCNGARAAYAARCAY ACNGARTGGATHYTNGARACNATHGAYCAYYTNMGNMGNMGNAARGCNMGNCCNGAYYTN CARMGNATHTGYCAYGTNGTNMGNMGNMGNTTYGGNYTNYTNACNATGGAYACNGARGCN AARYTNGARAARYTNGTNGAYGCNGARATHGTNATHAARGTNGAYTAYAARGGNAGYACN AGYTAYMGNAAYGCNGCNAARTGGMGNAARAGYATGTTYGGNTGYGCNATHCARAAYTCN MGNACNATHTCNACNAARATHATHGARGCNATHCARGCNGTNAAYMGNAGYAARACNGAR ACNGGNAARYTNATHAAYAAYGARAGYAGYAAYGCNTCNAAYTCNGARGARCARTCNYTN ACNAARTCNAGYAAR------------TCNMGNGGNGTNTCNTTYAARGARATHAAYTCN TGGYTNATHAARAAYTGYGAYGGNTAYAARGAYYTNAARAGYCCNYTNACNATHGTNYTN AARMGNGARGTNGAYGCNMGNMGNATHCARAARYTNGARGAYGGNGGNTTYATHGTNGCN CCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYAARCCNGAYMGNATGAAYGGNTTYGARGTN CARACNGARGCNGAYGCNATGATHGARMGNCARMGNMGNGAYATHYTNCCNAAYYTNCAR ACNCCNAGYAARACNTCNYTNAARMGNYTNGARTCNGGNGAYATHGARMGNGTNATHGAY CCNACNGTNGTNGAYACNATHGARGAYGAYAAYAAYTAYGCNGTNTTYGTNTCNTAYATH GARATHTAYAAYAAYTAYGTNTAYGAYYTNYTNGAYGAYYTNCCNTAYAAYCCNATHACN GGNTAYAARGCNCCNCARACNAARATHYTNMGNACNGAYTCNTAYGAYAAYATGTAYGTN CAYAAYTGYACNGARGTNGARGTNAARAAYCCNCARGARGCNATHGAYGTNTTYTAYAAR GGNCARAARMGNMGNAARGTNGCNCAYACNACNYTNAAYGCNGARTCNAGYMGNAGYCAY AGYGTNTTYAAYATHMGNYTNGTNCARGCNCCNYTNGAYGARMGNGGNGARGARGTNGTN CARGAYTCNAAYMGNATHTGYATHTCNCAYYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNGARAAYGARATHGCNTGYYTNAARGARGARAAYGARGARYTNGGNAARGCNYTNGAR GARYTNGAYTCNCARCAYTCNGARGCNATHGGNCARYTNATHGGNCARMGNAAYAARATG GCNACNGARATHCARGARAARGAYTCNTCNATHAGYCARTAYGARATGGARATHGARGAR YTNAAYTCNATHATHACNGARATG---GARAGYGARGARGARMGNAARTCNTGGGARGAR AARGTNGCNGCNTAYGGNGARGARYTNAARGGNACNMGNGCNMGNAARAAYATHTCNGCN YTNGARGAYGARATHTCNGARYTNMGNGARAARYTNCARAARGGNGGNYTNGTNATHAAY GAYYTNCAYATGGAYAARCARGARYTNAARGARGARYTNAARAARGCNAARGARGARATH AAYAGYAARGARTCNAARYTNAARGAYATHAGYTCNGARAARMGNCARYTNATHGCNGAR AARAARGARATGGARTCNAARYTNYTNAAYATGAAYGARCAYYTNTCNGARYTNGARGAR GARATHGARAARTGGCARCARATGAAYGARGARACNCARGTNGGNGARGCNGAYATGAAY GARAGYGARGARGARTGYYTNMGNYTNMGNTCNCARATHCARAGYATGGARTAYGARMGN GARGTNYTNAARGARGARTTYCARCAYYTNATHGARGAYGAYAARCCNTAYTCNCAYTCN CCNGAYATHCCNGCNGAYTCNCCNTTYCARAARATHTTYGARGARGARYTNAARGTNMGN GARAARYTNGARMGNGAYGARAAYATHATHGCNGARYTNAARGGNCAYGTNGARAARYTN CARTCNGARAARAARGARATH------------------------------AARAAYAAR GTNTCNGAY------------------------------------------TAYGARAAR AARTAYTTYGARTCNYTN------------------------------------------ ------------------------------------CCNTCNYTNAARTCNGGNCARGAR GTNGARGCNCAYTTYCARTCNGARYTNAGYMGNAGYAGYGAYYTNCARAGYAARATHAAY GTN--------------------------------------------------------- ------------------------------------ATHTCNGARCARGARGARCARATG GGNAGYATGGARMGNGAR---------------------ATHGCNAAYYTNYTNCAYGGN YTNTCNGTNTGYCARCARGARAARTCNGAYYTNYTNTCNGGNATHGAYMGNAARAARAGY ATHTGYGARCCNTCNTTYGTNCAR------CARATGGCNATGGGNGTNYTNGGNATGCCN CCNTCNAARGGNGAYAAYGTNGARCARCCNCCNMGNAAYGAYGAYGAYGTNGGNTAYAGY AAYCARGGNMGNTGYAAYTCNTGYTCNAAYAAYGGNAARAARGTNTAYGCNYTNCARGAR GARYTNGAYMGNATGATGGAR--------------------------------------- ------------------------------------GARMGNGARMGNATHTCNGCNTCN ATHCCNGARYTNGARYTNGARYTNGARGCNTCNCARATGCARATHGTNAAYYTNMGNCAR GGNYTNAGYAAYGCNCAYGCNACNATHGCNTGYCAYGARGCNGGNATHGTNGAYYTNAAY GARAARTCNCAYATGCARAGYCARAAYYTNGCNAARGCNGARATHGARGCNACNMGNCAR GARAAYACNATHGCNYTNYTNMGNCARAAYTCNGTNGGNAARGAYCARYTNYTNACNGAY YTNCARCARAARYTNAGYTCNGTNGTNACNGTNYTNACNCCNGAYCARYTNAGYATHYTN ------CCNAAYCAYTCNACNGCNTAYYTNGCNYTNGARTAYAARGARMGNAARGCNATH CARCAYTTYGAY------CARGGNAARCARGARTCNACNCCNGTNAAYAGYTCNTGYGCN GTNGAYATGAAYCCNGGNCARCARGAYGAYGAYGAYGARAARTGYGAY------------ ---MGNATHYTNYTNATGGARGARGARYTNTCNAAYYTNCARAARCARYTNAGYGARAAR GAYGCNGTNATHTCNGARYTNCARAARTCNAAYTCNTCNYTNYTNGGNYTNYTNGAR--- AARGGN---GGNGGNGGNGAYAARACNGAYCCNGTNGCNGTNTAYAARYTNAARTCNGAR YTNCARAGYYTNMGNMGNGARAARCARCARATGGTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GCNCARAARCAY YTNYTNAARGARGAYYTNTCNAGY---TAYCCNCARAARGAYATGGCNTCNTCNGGNAGY GGNTCNGGNCAYCCNTCNYTNGTNCARMGNACNGCNGGNAARGAYTGYYTNCCNATHGAR YTNATHGGNCARGGNMGNTTYGGNGARGTNTGGAARGGNAARTTYAARGGNGAYATHGTN GCNGTNAARATHTTYACNTCNYTNGARGARGARAGYTGGAGYCARGARMGNGAYATHTAY AAYATGGGNYTNYTNMGNCAYGAYAAYATHYTNGGNTTYTAYGCNTCNGAYACNCCNTGY MGNAARGCNTGYACNGTNCAYATGYTNATHATGCAYTAYCAYCAYCAYGGNTCNYTNTAY GAYTAYYTNAARYTNAGYGAYATHGAYATGGARGARATGYTNACNYTNGCNCAYTCNGCN GCNGCNGGNYTNAGYTAYYTNCAYACNGARATHAARCARGGNACNGGNACNAAYGGNAAR CCNTAYATHGCNCAYMGNGAYATHAARTCNAARAAYATHYTNGTNAARGCNAAYGGNGAR TGYTGYATHGGNGAYTTYGGNTAYGCNGTNATHGARTCNGAYGGNTGGMGNGAYAARGTN AARAAYYTNCARGTNGGNACNAARMGNTAYATGGCNCCNGARYTNYTNACNGARMGNYTN CCNMGNAAYAAYTTYCAYGCNYTNYTNTGYGTNGAYGTNTAYGCNTTYGGNYTNGTNATG TGGGARATHGCNMGNMGNGCNMGNCCNTTYTCNGARGARTAYCARYTNCCNTTYTGGGGN CARGTNCCNCCNAAYCCNAGYATHGAYATHATGAARGARGTNGTNGTNGARAARCARATH MGNCCNCCNGTNCCNAAYATGTGGGARAARCARCCNYTNATGGTNGARATGGAYAARYTN ATHACNGGNTGYTGGGCNCARAAYCCNTCNTGYMGNYTNACNATHYTNMGNGTNAARATH AAYYTN------------------------------------------------------ ------------------------------------------------------------ ATGYTNTTYAAYYTNGARAAYTGGMGNCARGGNMGNGARYTNYTNTGYGAYGAYYTNAAY MGNAARYTNGTNTTYMGNAARCAYTTYGAYTGYGTNTCNMGNTTYGGNCCNMGNGTNGCN AGYTGYATHYTNATHMGNACNCARATGTTYAARAARGCNGTNACNGAYGCNGGNATHGTN CCNCAYAARACNYTNCAYGAYATHACNTGYAAYTTYGCNGARAAYATHGTNAAYTGYYTN GARMGNCCNYTNGCNMGNGCNTGYCCNATHGAYGTNGTNGAYACNATGGTNAGYGCNYTN CAYMGNTTYYTNCCNCCNGCNTGYGCNCCNGTNCCNGCNATHTAYAGYTCNGAYGGNYTN AAYAGYCAYGARACN------------------GTNYTNGARACNGTNATHYTNGARGGN GGNGAYGAYATGGCNGAYTCNGGNATHGARGTNGAYATHATGAGYYTNATHGARGCNGAR CARGAYCCNGTNTCNGAYCCNACNAAYTAYTAYCARATHCARAGYACNGTNGTNGTNGGN AGYCCNGTNACNGARATHAARCAYGCNAGYATGCCNATGMGNGCNAAYYTNAARCARCAR YTNCARMGNCARCARYTNYTNGARCARGARAARMGNAARAAYGARGCN------------ CAYATHACNGGNTCNGCNGGNATHAAYGTNCCNCAYGTNGTNCARTCNGCN---GTNCCN ACNAAYGTNYTNCARGTNAARACNAARYTNCARTAYCCNACNAARTAYCAYGTNMGNCAR AGYCARAARMGNCARGTNGARCAYTTYYTNAAYGARACNCARGGNAGYCAYTTYCCNATH YTNTCNYTNCCNGCNCAYGTNGTNTCN---TCNGCNCARGAYCARCAR------TAYAAY CARACNTGYAGYAGYGCNCCNGARCCNGAYYTNCCNAGYCCNYTNYTNTCN--------- ACNGGNGCNGARTTYATHCCNACNGGNTTYGAYYTNYTNGGNGARGTNTCNTCNATHGAY CCNYTNGARATHGAYAAYYTNYTNGGNGAYGGNAAYTAYYTNGARATHCARCCNTCNYTN GGNGGNTCN---YTNGTNCARGAYGGNYTNGTNTCNGGNTTYGAYTGYYTNGARACNGAR GCNTCNAARAARACNTCNAAY---------TCNTGYCCNACNACNCCNTAYCAYTGYTCN GARYTNGCNCAYACNGGNATHATGTCNGTNCARGAYGARATGTGGMGNAARGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNMGNMGN GTNGCNTGGMGNCAYYTNYTNAAYATHTTYCCNGGNAAYATGTCNGGNAARGAYMGNTTY GAYTAYATGAARMGNAARGTNGARGARTAYMGNAARYTNMGNGAYGARTGGATHGARCAY TTYCAYACNAAYACNYTNYTNCARGARMGNYTNCARMGNYTNCARGAYGCNYTNAAYGCN TAYGGNCCNAAYTCNCARCAYTTYYTNAARGAYTCNGTNGAYAGYCCNTGGGARMGNGCN GTNGCNGGNAAYAARGTNCCNTAYTAYATHAAYCAYGARACNGARACNACNCARTGGGAY CAYCCNCARYTNACNGCNYTNATGGAYGCNYTNATGGARYTNAAYAARATHMGNTTYGCN GCNTAYMGNACNGGNATGMGNYTNMGNATGYTNCARAARAARATHTGYYTNGAYATGGTN TCNYTNCARACNGCNGTNGARTCNTTYGAYAGYCAYGGNYTNMGNGGNMGNAAYGAYAAR YTNATGGAYGTNGGNGARATGATHGARTGYYTNTCNACNATHATGGARGGNACNGCNGCN GARCAYCARGARYTNGTNAAYGTNCCNYTNTGYGTNGAYYTNACNYTNAAYTGGATHYTN GAYGTNTAYGAYAGYGTNMGNAGYGGNAARGTNMGNGTNYTNTCNTTYAARGTNGGNATH GTNYTNYTNTGYCARGCNCARYTNGARGAYAARTAYMGNTAYGTNTTYMGNYTNATHGCN GAYACNAAYGCNTTYGCNGAYCARMGNAARATGGGNYTNYTNYTNCAYGAYTGYATGCAR ATHCCNMGNCARYTNGGNGARATHGCNTCNTTYGGNGGNAGYAAYATHGARCCNAGYGTN MGNAGYTGYTTYGARAARGCNAAYGGNMGNCCNGARATHGARGCNTTYCAYTTYYTNGAY TGGYTNAARYTNGARCCNCARTCNATHGTNTGGGTNCCNGTNYTNCAYMGNYTNGCNGCN GCNGARACNGCNAARCAYCARGCNAARTGYAAYGTNTGYAARGAYTTYCCNATHGTNGGN TTYMGNTAYMGNTGYYTNAARTGYTTYAAYTTYGAYGTNTGYCARAAYTGYTTYTTYTCN GGNMGNACNGCNAARAGYCAYAARYTNACNCAYCCNATGCARGARTAYTGYACNACNACN ACNTCNGGNGARGAYGTNMGNGAYTTYTCNAARGTNTTYMGNAAYAARTTYAARTCNAAR MGNCAYTTYAARAARCAYCCNMGNMGNGGNTAYYTNCCNGTNGAYTCNCAYYTNGARGGN GAYAGYYTNGARAGYCCNAAYCCNTCNCCNCARCAYAGYATHTCNCARGAYATGCAYTCN MGNYTNGARATGYTNACNAGYMGNATHGCNGARGTNGARCARMGNCARGGNGAYCCNTCN GARYTNGARAAYGARAAYAARCCNGTNACNGAYGARCARGAYGGNGTNGARGAYGARCAY CAYYTNATHGCNCARTAYTGYTGYAGYYTNAAYGGNGARCCNTCNTCNCAYGCNYTNAAR AGYCCNATGCARATHATGATGGCNGTNGAYGCNGAYCARMGNCARGARYTNGARACNATG ATHMGNGAYYTNGARGAYGARAAYAARACNYTNCARATHGARTAYGAYMGNYTNCARATG GCNGCNCARGARMGNGCNGAR------------------AGYATHCCNMGNGGNYTNGGN GAYGGNAAYTCNGGNAAYMGNGAYGARGARATGYTNGCNGARGCNAARYTNYTNMGNCAY CAYAARGGNMGNYTNGARGCNMGNATGMGNGTNYTNGARGAYCAYAAYCARCARYTNGAR GCNCARYTNGGNMGNYTNMGNCARYTNYTNGAYCARCCNCARGGNGAYMGNAGYTTYATH TCNATGGAYTCNTCNTCNMGNACNACNCCNATGACNACNCCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AAYYTNAGYGCNAAYAGYAARAARCCNAARAARAARAARGAYAARAARGAR AARACNAARGCNGARGAYAARGTNATHTCNGGNAARAGYGTNCARAGYMGNAAYAGYMGN GCNYTNGARTAYYTNMGNATGTGGAAYACNGTNMGNGARTCNTGGAARTTYAAYAARATG YTNCARACNCAYYTNYTNCAYYTNGTNTAYGAYGCNATHGTNGTNAAYGAYGAYGAYTTY GAYATHYTNYTNYTNTAYYTNAGYGGNYTNAAYGGNAARGCNAARGARACNACNCAYAAR GARGCNYTNAARTTYGTNGARGGNGARCCNGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GCN CCN---ACNGARGARCCNTAYYTNCCNTGYGAYGAYYTNATGAARTTYCARAAYGCNYTN AARAARYTNMGNYTNATHGAYGAYMGNATHATHCAYGCNYTNAAYACNAAYYTNCCNACN CARTCNTTYMGNCARGGNGTNGAYGCNTCNGCNGARTGYAARCAYYTNTAYGAYGAYATG CARYTNTCNTAYGARCARMGNGAYAARTGYATHCARCAYTGYYTNMGNATHGTNAAYGAY GAYGTN------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGGTNGAYACNGAYATHYTN TGYGTNYTNGCNGGNYTNTGYCAY------------GAYYTNGGNCAYGGNCCNTTYTCN CAYACNTTYGAYGGNAARTTYATHCCNYTNGCNACNAARAAR---AARTGGACNCAYGAR CARGCNTCNTGYGAYATGYTNGAYCAYYTNATHAARGARAAYAAYYTNATGGGNACNAAY GGNGCNYTNCAYAARCAYGGNYTNMGNGARAAYGAYATHACNTTYATHAARGARYTNATH TAYGGNCCNYTNGARGARACNGAYCCNGAYTGGCCNTAYMGNGGNMGNACNAARGAYAAR GCNTTYYTNTAYGARATHGTNTCNAAYAARMGNACNGGNATHGAYGTNGAYAARTGGGAY TAYTTYGCNMGNGAYTGYCAYCAYYTNGGNATHGGNAAYAARTTYGAYCAYAAYMGNTAY ATGAARTTYATHMGNGTNYTNGARGTNAAYGGNAGYTGGCARATHTGYACNMGNGAYAAR GARATGGGNAAYYTNTAYCARATGTTYTAYACNMGNTAYACNYTNCAYMGNTGYGCNTGY CARCAYCARGCNTAYTGYGCNGCNGARTTYATGATGGTNGAYGCNYTNYTNGARGCNAAY GARCAYTTYYTNTTYCCNGGNAARGAYGTN------AARYTNTCNGAYTGYATHGGNGAY ATGGTNGCNTTYTCNMGNYTNACNGAYCAYATHYTNTGGGARATH---AAYGARCARMGN ATHGARYTNCARAARGCNCARGCNYTNATHAARMGNYTNYTNTGYMGNGAYYTNTAYGTN TGYYTNMGNGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GTNGARGCNAAYTCN CCNGCNGAYAARGARCARGAYAGYATGGGNYTNATGTAYGARCAYTAYYTNAARGARATH GTNGAYGTNYTNGARAARGAYCCNGARTTYAARAARAARYTNGARACNGCNAAYGTNTCN GAYATHAARAAYGGNAAYATHGCNATGCAYYTNGAYYTNGTNAAYCAYACNATHMGNTCN TCNYTNGAYGARATHAARMGNMGNGARGTNAGYMGNYTNMGNGAYYTNACNMGNGTNCAR YTNCAYGTNAARAAYGGNATHGARAARATGGARACNCCNGGNCAYYTNGAYYTNAARAAY CARCAYAGYTTYGARATHAARGAYYTNGARGCNYTNATHAARAARACNACNTCNGAYYTN GARGARATHGAYCARAARMGNAARGARGARTTYAARGARTAYGARATGGARAARGARTAY GARAARMGNCARCAYYTNAARGARYTNCCNGARGARGARAARAARAARGARGARAARAAR GARGARGARGGNAARAARAARAARAARGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARTAYATGCARMGNACNYTNAARATHCARCCNACNTAYGTNTTYAARGARYTNGAR AAYTCNAARACNCCNTAYGGNGCNACNGTNATGATHAAYAAYATHGARTAYGGNACNGGN TAYGCNTCNTCNAARAARATGGCNAARCARGARGCNGCNAARGARACNYTNAARATHYTN ATHCCNGAYYTNTCNACNAARATHTCNGAYCARGARYTNAARCAYAGYATHTCNGAYYTN TCNTTYTTYGAYGARATHAARGTNGARGAYCCNMGNGTNTAYGARYTNGGNAAYAARGTN GGNCARCCNAGYCCNTTYCARYTNYTNMGNGARTGYYTNMGNMGNAAYTTYGGNATGGGN AAYACNCARTGYGAYGTNAAYACNACNGCNYTNAARAAYCARAARTGYGARTTYTCNATH AARGTNGGNAARCAYACNGCNACNGTNGTNGCNAARAAYAARMGNGAYGGNAARCARYTN GCNGCNCARGCNATHYTNGCNAARYTNCAYCCNCAYGTNCCNAGYTGGGGNTCNYTNYTN MGNYTNTAYGCNACNAAYGTNGARAARCCNATGGARAARGTNGARGARATGAAYGARATH AARACNCAYGTNCCNAAYAARGCNGTNYTNGARAGYYTNMGNYTNGARATGMGNAARYTN CAYAARCARAARGARGCNATHCARTCNAARGGNAARATGGTNATHTCNAGYMGNGAYYTN CCNATHAARATGTCNGGNGTNGAYYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNACNTTYGTNGTNGARCAYAARGGNAARCARTCNCARTTY AAYCCNGGNCARATHNNNGANATGATHTAYGGNAARATGYTNGARACNGCNCARAGYCAY AGYGGNGCNGGNTCNAARGAYGCNGTNATHGCNGTNCCNTCNGARTTYAGYCARCARCAR MGNGAYTTYGTNAGYGARGCNGCNACNMGNGCNGGNTTYAAYATHATGMGNGTNATHAAY GARCCNTCNTCNGCNATGYTNGCNTTYGAYGCNGGNCARYTNGAYGARACNGARCAY--- TTYAARGCNYTNGTNTAYMGNYTNGGNGGNACNTCNCAYGAYGCNACNGTNATGGAYGTN AARCAYGGNATGTAYTCNATHGCNGCNAARATGACNGAYAGYCARTTYGGNGCNGAYAAR TTYACNGAYGTNYTNMGNGAYTTYTTYGCNACNGARTTYAARAARCARTTYMGNTCNGAY YTNACNGAYAAYAARMGNTCNYTNAGYAARYTNAARYTNGCNGCNGARMGNTGYAARCAY GCNYTNTCNACNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARGARGAYGAYGARGAYGTNATHGGNMGNACNGAY GAYGARTCNGARGAYGARACNGARACNGARGAYGAYGAYGARGCNGAYGARGGNACNAAR MGNGGNGARCCNAAYAARTTYGAYGGNYTNTGYGAYGGNGTNYTNAAYGCNATGGCNYTN GTNCAYGCNACNYTNCARGAYYTNYTNGAYATGAARGAYGARATGYTNMGNCAYTCNYTN CCNCCNACNYTNYTNATHCAYYTNGCNATGGTNAGYGGNMGNGTNTTYMGNAGYATHAGY GAYYTNGGNATGCCNGTNAAYGARYTNGTNMGNYTNGTNCAYGTNTAYTCNACNCCNTGG GARGARAARAGYGCNGCNYTNAARAARYTNCAYGARGAYTAYGAYAGYAARCARMGNCAR YTNAAYATHGCNATHAARMGNYTNCARYTNGTNGAYGCNCAYTCNAARMGNGTNGCNAAR GAYAARMGNATHATGAAYTGGGARAARYTNTTYTCNAARATGACNAGYGCNAARGGNCAY GGNMGNMGNTGGAARTTYYTNATHGARACNATHAARCARAARGCNAARYTNGGNYTNGAR CAYGTNCARGCNTAYACNCARGGNYTNGARGARTCNTCNGARTCNGARGAYGARGARTTY CCNACNGARCARGCNCCNACNATHGCNGCNGARGGNGARGARGARGARMGNGARACNYTN GGNTCNCARGGNGCNAAYGGNACNGARGARAGYMGNAAYGGNGARGARGAYAGYGTNGAY GARGARGAYAGYGTNGAYGAY------------AARMGNGGNMGNGAY---GAYGARACN GARTCNMGNGCNAGYGARGCNTCNGGNGAYTCNGARGGNGCNCARTCNGAYACNGTNCCN ACNGTNACNATHCAYATHGGNCCNGGNGCNGAYGTNGAYGTNGAYGGNACNGCNAGYCAY TCNACNTCNCCNAARAARGTNCAYTTYGARGAR------GCNMGNTCNGCNGCNATHAAR CCNCCNGTNMGNGAYTCNAGYACNTGGACNGARCARCCNGAYTAYGAYMGNTCNYTNTTY ATHMGNATHTTYTGYCCNGARGGNYTNAARCARATHGGNAGYGGNATHAARTGYTCNYTN TCNTAYAAYAAYAAYATGTTYAARACNTCNTTYYTNGAYGGNCCNGAYGARGARYTNTCN GAY---GARAGYCCNAAYGAYGARGARAARACNCCN---AARMGNCCNCARGCNGCNCAY AARGGNAARGAYMGNTCNAAYCCNGARGCNACNAARCARCCNGAYAARAGY------AAR TAYAARMGNTAYTTYGARTTYGARATHCCNYTNCCNGAYGARGTNGTNAGYGGNATHYTN YTNYTNGGNGARAARCCNGCNCCNGARCCNGARAAYATHCARATH--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GGNATGATHGGNGGNTTYTAYGGN YTNATHATHATHATHTGYATHGTNATHATHATHCAYMGNAAYYTNAARTAYAARGGNMGN YTNAARMGNTGGGARACNCAYCARYTNTCNACNATGAARACNGGNACNGCNTTYGARAAY MGNAGYCARGTNTCNGARCCNTCNCAYGTNTGGTCNATGGARATGGCNAAYAARCARGGN GCNGCNAGYACNTAYTCNMGNTCNCAYGCNGAYCCNTAYGGNAARMGNYTNGCNGAYGAR ---TCNAGYGTNTTY---------------GAYCAYGAYGARACNTTYCARCARMGNAAR YTNATGAAYGCNMGNCARGARMGNGARMGNCAYMGNGAYCARACN---GCNTCNGARAAY ACNTCNTTYACNGAYGAYGAYGAYCCNGAYCAYTTYGTNGARAARGTNATHMGNCCNMGN GTNMGNGCNMGNGAYMGNMGNGARCAYMGNCCNCCNTCNTTYGARGARGCNATGGCNGAY MGNMGNCAYGARCAYTCNTCNGAYGARGARGARGARGARAARGARAGYGAYGAYGAYTCN ACNMGNAARMGNAARYTNTCNACNGARGARTCNTCNCARTCNTCNGGN------------ ---TCNGAYTCNCARTCNGARTCNGARGAYAGYGGNAARGAYCAYTCNMGNAARGGNMGN GGNGCNGCNGCNMGNAARGGNMGNTGGAARCCNGAYAARAARTCNMGNMGN---MGNCCN TCNTCNGCNGAYGARGARAAYTCNTCNYTNCAYAGYGAYGCNMGNMGNAAYCAYCCNCAR CARCARCARCARCCNCCNGTNCARYTNGCNGGNATG---------CCNTAYGGNGGNTAY CCNCCNGGNCARTTYGTNCCNGTNATGGCNGGN---CAYCCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GAYGARATHACNTGYCCNMGNTGYGARCARAARACNCARYTNAAYTCNMGNGGNGTNAGY GGNYTNCCNTCNGAYTCNGTNYTNGARGAYATGATHCARTCNGAYTCNGAYGAYAARAAR CARATHGARTGYACNAGYTGYAARGCNGGNGAYAAYGCNATHGCNMGNTGYMGNACNTGY GARAAYYTNYTNTGYCCNAAYTGYGTNACNGCNCAYCARTAYATGMGNTGYTTYGARGAY CAYCARGTNGTNACNTTYGAYGARATGATHAAYAGYGGNGARGGNATHGARCAYYTNMGN AARCCNATHTTYTGYAAYGTNCAYATHATHGARAGYATHAARYTNTTYTGYTGYAARTGY YTNGTNTGYGGNGARTGYGTNTCNAARYTNCAYGCNGGNCAYGARAAYYTNATHAARCAR YTNACNGARGCNGTNTCNACNAAYAARGAYACNYTNATGCARYTNACNGGNGARTGYGGN AARAARYTNMGNGARTGYCARGAYYTNAGYTGYTCNYTNAAYTCNGCNYTNGARGARYTN CARATGCARAARGAYAAYACNNNNNNNYTNATHGARGARACNTTYCARAGYTAYAARGTN ATHYTNGARGARACNAARAARAAYTTYYTNAARGAYYTNGAYGARYTNCAYGARCARMGN GARYTNGGNCAYYTNGARAGYATHCARAGYGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTNAARAAYTCNTCNAAYAAR GARAAYMGNTTYAARATGACN---GAYGCNYTNCARAARTCNGGNYTNYTNGARGTNGCN GTNAARACNGGNAAYTTYATHMGNMGNAAYCAYCARYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATGTCNCCNCCNGARMGNTGGAAYGAYTAYTCNCCN ATGGGNAARGTNATHCCNGGNACNAAYYTNATGGCNYTNAARGTNCCNYTNAARCARGAY YTNTTYMGNGGNAARAARACNGARGAYATGTTYACNCCNACNGTNTTYATHGARAARYTN MGNGARCAYGGNCARAARYTNGGNYTNGTNATHGAYYTNACNTTYACNAAYAARTAYTAY AAYCCNCARGARTTYACNGARGCNAARGTNAAYCAYATGAARATHTTYACNGARGGNCAY GTNATHCCNAAYAAYGAYGTNTAYMGNCARTTYGCNGCNGCNGTNAARCARTTYAGYAAR GARGGNCAYGTNATHGCNGTNCAYTGYACNCAYGGNGTNAAYMGNACNGGNTAYYTNATH TGYMGNTAYATGATHGARGARATGGGNATHAAYCCNGCNGARGCNATHGAYYTNTTYAAY GARGCNMGNGGNCAYAARATGGARMGNAARAAYTAYYTNGARGAYYTNAARTGGMGNAAR AAR---------------CCNMGNCARCAYTAYMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TTYGTNMGN GGNAGYCCNGTNTCNGARACNACNMGNAGYTCNTGYGGNAGYCCNACNCCNAGYGAYACN AGYTCNCARAAYGCNACNGTNACNCARCARGCNYTNACNGCNGCN---GCNATGAARMGN GARGARACNGCNAARYTNACNGCNTCNYTNAGYAAYTAYTAYAAYGARGARYTNATHGGN CAYGTNYTNGGNTGGCARGCNGAYCARGTNGARAARCARGCNGCNAARYTNTGGGARGAR TCNATGAGYAAYGGNAGYYTNCARTGYGCNGARATHTCNGTNCARYTNAARMGNGCNMGN TCNCARGTNMGNATHGCNGARATHCARTCNACNYTNCAYGARCARMGNATHATGTCNTCN GAYCARCARMGNCAR------------------------------TAYCARGTNTCNTCN MGNYTNMGNGGNGGNGARAGYYTNACNAAYYTNAARMGNAARGARYTNGARYTNTAYMGN CARTTYTCNTCNGAYATHCCNYTNGTNGGNTTYGTNYTNGTNTTYGCNTTYGCNCCNGGN GGNGTNYTNATHTTYCCNYTNGCNTAYATGTTYCCNMGNTTYYTNYTNTCNCARCAYTTY TGGACNCCNCARCARAARGTNGAYTTYCARAARATHGAYYTNAARAARMGNYTNAARCAY CAYAAYGGNATHYTNGAYTCNGTNGARAGYCAYTCNGAYGCNGARMGNGCNAARGTNACN AAYGTNATHAGYAARYTNGAYACNTCNGTNACNYTNAGYCCNGARGARATHYTNTCNYTN MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CCNYTNTTYGAR GGNMGNCCNTAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARTGYACNGGNGGNGARMGNGGNGARATHMGN CARGAYATHGARGGNCAYYTNAARMGNAARATHGGNAAYTCNAGYGAYTGGAARCARGTN AARAARTGYYTNTCNAAYAAYTAYGGNGAYAAYGARMGNACNACNTTYGTNGARGARATH TGYGGNYTNGCNAARAARCAYGAYGARYTNTGYAARAARTTYGARYTNCAYMGNAARGTN GARACNTTYTTYAAYGARCARATHGAYMGNYTNAARTGYACNTGYGAYATHYTNMGNMGN CAYAAYGARCAYCARCAYGTNAAYGTNCCNYTNCCNGCNGTNATHGGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARYTNATHACNTGYCCNATHTGYYTNCARGTN CCNTTYGCNGGNAARATHACNAARTGYGGNCAYACNTAYTGYTGGGCNTGYATGYTNCAY TAYYTNAARYTNGGNGAYAAYGAYTGYMGNAARTGYCCNATHTGYTAYGAYGCNGTNAAR CARGARGAYYTNAARAGYATHMGNTGGATGGTNGTNCCNGAYTTYAARGTNGGNGAYGAR ATHGARATGAARYTNATGMGNAARAAYAARGGNAGYGTNTTYGTNGTNCCNATHGCNGAY TGGATGGAYMGNTAYGGNGARCCNATGAAYATHGARGGNGGNAAYACNACNAARTTYATG AARYTNYTNGTNGCNTCNTCNGAYCARATHAARAARGARGTNATHGAYGTNGARMGNGCN GCNYTNTTYTCNCARATGATHGAYGCNGARGARTGYGARGCNTGYTTYATHCARATHGCN YTNGAYYTNYTNGAYAARMGNGARGCNAGYYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATHCCNCARGARTCN---------YTNCARTCNATHGAYAGYYTN AARTCNYTNGTNTAYGARCARTGGYTNGTNTCNGAYYTNGCNGARATHGCNGARCCNACN YTNCCNGTNGGNGTNTCNGARGTNGARAARYTNGAYYTNATHAGYAGYTAYCCNYTNCAR YTNATHTCNGTNGTNGAYGTNGGNTTYCCNYTNTTYGGNCARAARCARAARYTNCARGGN CARGAYAAYCCNAAYGARAARGTNTCN---GCNGAYAARCCNTTYCARCCNGGNTGGGAR CCN------------------AARCCNTGYMGNATGYTNATGATGTCNYTNACNGAYGGN TTYGARACNGTNCARGCNATHGARTAYCARCCNGTNAARAGYYTNAAYATGTCNYTNAAR GCNGGNACNAAR------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNGARAAYAAYGARYTNAAY AARGARCARGCNMGNGTNAAYACNGARGGNAAYGARAAYGAYGGNGAYTAYGAYGGNGGN YTNGARGARGAYGTNATHGAYGAYGARTAYGTNAARAARCAYAARCCNCCNACNGCNCCN TCNAGYATGGTNYTNTTYTAYACNTGGATGATHYTNGCNGTNGTNATHATGGTNATHGCN GTNTCNACNTAYGARACNTAYTGYAARGGN---CAYGCNACNGCNAAYMGNAAYCARTCN MGN---GARGAYMGNAARMGNYTNATHGARCAYGARTAYGTNYTNAGYYTNYTNGAYYTN CCNTGGGARGCNGTNYTNTGYAAYCAYGTNYTNCCNTGYYTNAGYAGYCCNCARYTNTTY MGNTTYMGNTGYGCNAGYCARAGYTGYYTNGARYTNGTNGARYTNTTYTTYAGYMGNCAR TTYCAYYTNAGYACNCAYCARYTNGGNGAYGAYTGYACNGCNAAYGCNTTYGCNGTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CCNAARGAYYTNACNGGNMGNGCNAARGTNMGNGCNYTNGCNGARYTNATHAAY AGYGGNATHCARCCNYTNCARAAYYTNATHGTNYTNCARAARATHGGNGAYGGNAAYGCN GARTGGGCNCAYTTYTTYATHAAYAARGGNTTYGCNGCNATGGARAARATGYTNCARGAR ACNGCNGGNAARTAYTGYTAYGGNGAYGARGTNACNATHGCNGAYATHTGYYTNGTNCCN CAR---YTNGCNGCNTCNAARMGNTTYAAYGTNGAYCARTCNCCNTAYCCNACNATHACN MGNATHTGYGCNGCNYTNGARGGNYTNGAYGCNTTYAARGARGCNGAYTTYMGNMGNCAR CCNGAYACNCCNGARGARYTNMGNATHGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNACNACNYTNGCNGGNCAYGTNGGNTGYCCNYTNCCNGCNACNACN GAYCCNAGYAARATHGARGARATHMGNMGNACNGTNTAYGTNTCNGAYYTNGAYCCNAAR GTNACNCCNGARATGYTNYTNACNTTYTTYTCNCARACNGGNGARATHAARTAYATHMGN ATGGCNGGNGAYGARAGYGGNACNACNMGNAGYGCNTAYATHGARTTYACNGAYCARMGN TGYATHGCNCARGCNYTNAGYTAYAAYAAYGTNGTNTTYCARGGNMGNACNGTNAGYGTN AARCAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNATHCAYGCNTTYCAYMGNGAYCARAARGAYGGNMGNGGNAGY ATHAARAGYAGYGTNYTNGAYAGYCCNAGYGARAAYATGAARTAYATHGAYYTNTCNTCN CAYAAYATHAARTAYCAYGGNAGYCARGGNYTNYTNAAYTTYAGYTGGYTNGCNGAYCAR ACNGCNAAYACNGARGCNATGGAYATHGARATHGAYGARCARTGYATGTCNACNMGNAAR TCNGAYGGNCAYATHGARATGACNACNYTNYTNMGNGCNTCNCARACNATGATHGTNGAR GARGARGAYACNCCNGAYATHYTNGAYGARCCNATG------------------------ ------GAYAAYAAYCARAARTAYGGNAARATHGCNCARMGNYTNATHGARATGGCNGAY TCNTAYGGNACNGGNATGTCNGARCARGGNGGNCARGGNGCNGCNGCN---------GCN CCNYTNACNGAYYTNGARMGNGAYATHATHGCNTGGATGMGNTCN---AARGAYAAYATG TCNAARGARATHGARGARAARYTNGCNGARGCNACNAGYACNGAYATHGGNAAYGGNTAY GAYMGNTTYMGNAARACNGTNCARAAYTCNATGAGYCAYGARATGAGYTGGAAYCARYTN GCNTTYTTYTTYTAYTCNACNAARGGNGTNATHTCNGCNYTNGGNAARGGNACNAAYGCN GCNAAYCARGTNAARGARTTYACNYTNMGNTAYATHAGYGAYACNTTYACNTCNTGGATH ATGGAYCARGGNGGNTTYGAYAGYATGYTNAGYAAYAGYGARTCNGAYCARGARGTNGAY TAYGAYGGNGAYATHCARAAYMGNGGNAARAARAARGGNGTNATHCCNYTNGTNTCNACN AARGTNGTNATGGARGTNGAYGAYAAYMGNYTNGARGGNMGNTGYAAYGTNTTYCARATH GTNTAYGARGAYAARMGNGAYTTYCCNACNYTNTAYGTNATHGCNCCNACNCARAGYGAY MGNCARTCNTGGYTNACNACNATHMGNGAYGCNGCNYTNCARATHGGNGCNCARTTYTTY GCNAARTAYCAYCCNGGNGTNTGGACNAARMGNYTNGGNTCNTAYAAYTGYTGYGAYCAR TGYGAYMGNAAYGCNATGGGNTGYAARTGYGAYACNGTNGAYMGNACNTCNATGCCNCCN GTNCCNCCNCCNMGNACNGAYTTYTCNTCNGCNAARAARGTNGTNATHGCNATHTAYGAY TAYGARCCNACNGARGCNAARGAYYTNGARYTNYTNCARGGNGAYAARTAYACNATHATH GAYGAYTCNGARGARAAYTGGTGGYTNGCNAARAAYGAYMGNGGNGARCARGGNTAYATH CCNGCNAAYTAYGTNAARATHAAYTGYGGNYTNGARATHTTYGARTGGTAYTAYAARGAY TGYTCNMGNGARMGNTGYAARCARATHYTNATGCAYAGYGGNAARGARGGNTGYTTYYTN GTNMGNGAYTCNGTNAGYAGYCCNGGNGAYTAYACNYTNTCNATHTTYACNACNGARGGN GARGGNAAYGTNMGNCAYTAYCARGTNAARATGAAYGARYTNAAYCARTAYTAYATHGCN AARAAYCAYATHTTYAGYAGYATHCCNGAYYTNATHTAYTAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GCNAGYYTNAAYTAYGGNCCNAARAARCCNGCNYTN TCNACNGCNGGNCARGTNCCNTGGGTNMGNYTNAARMGNMGNGARTCNYTNGGNYTNGCN GAYATHATHAARGGNAARGCN---CARAGYCCNAAYACNGTNAARATHGCNGTNTCNGAR CCNTCNCAYYTNYTNCCNGCNCCNAGYTTYNNNNNNACNCCNYTNATHGTNACNACNGAY ACNAGYMGNACNMGNGTNATHGAYACNCARACNGTNGTNTCNGCNYTNMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GCNTCNGARAARGTNGARGARATHGAYYTNAARGCN GARGARGARTTYAAYATHGARAARGGNMGNYTNGTNCARCARTCNMGNGTNAARATHATH GAYTAYTAYGAYMGNAARACNAARCARGTNGARYTNCARAARAARATHCARATGTCNAAY ATGCARAAYAAYTCNMGNYTNCARATHYTNMGNAARAARGAYGARTAYGTNAARGAYYTN YTNGARGARGCNMGNCARGARYTNYTNAARYTNCCNATGCARAAYCCNGARAARTAYAAR GCNYTNYTNYTNCARYTNATHATGCARTCNYTNACNMGNTTYATGGAYTCNTTYGTNCAY ATHAARTGYAARMGNGARGAYGTNCARATGATHAARAAYTCNGTNCCNGCNYTNTGYAAR CARTAYAGYACNATHACNAAYGGNAARTAYAARGTNCARYTNACNGTNGAYGARGARGAR TTYYTNCCNTCNGARATHTGYGGNGGNGTNGARATGAGYACNATGGGNGGNAARATHACN ATHGTNAAYACNYTNGAYGARMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MGNTTYTAYGCNGTNAARCCNTCNAARGAYATG YTNGAYTCNAGYAAYATGTTYGCNCAYGAYAARATHGTNCARYTNGTNAARAAYACNACN GARAAYAGYMGNYTNCAYGTNATHTTYGAYACNAARAARAARTAYACNTAYCARTTYGAR TCNGCNYTNGARMGNGARAGYTTYTGYYTNCARATHMGNCARATGAARTCNYTNCAYGCN CARGARCARGARACNGAYAAYGTNTCNATHTTYGTNGGNACNTGGAAYATGGGNAARTCN GCNCCNGTNGARTCNYTNAARTAYCCNGTNGTNTTYATHCARMGNATHGARTCNTTYAGY GCNTGYCAYMGNYTNCAYAGYCCNGCNYTNTCNGAYGARGCNAAYAARTCNYTNTAYGGN AAYTGYAAYCAYCCNAAYGGNCAYGGNCAYAAYTAYAARGTNGARGTNACNYTNAARGGN CCNGTNGAYCCNGARACNGGNATGGTNATHAAYATHGTNGARYTNAARAARTAYATHGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CARGCNAGYGTNYTNCARAAYGTNGTNCARCAR---GCNACN CARGTNTCNCARCARCCNCARCARACNYTNCARACNACNGCNGCNTCNAGYGCNGCNGGN TCNACNTCNGCNATHCCNCARATGYTNTTYYTNAAYCARGTNACNATHAAYGGNCARACN TCNTTYGTNYTNGTNGAYGCNAAYAAYAARCCNGTNCARYTNCCNCARGGNATHCARGTN ATHAAYYTNCCNACNCCNCARATHTCNGGNCARACNATHCARATGCCNGGNGCNGAYACN GGNGAYGARCCNYTNTAYGTNAAYGCNAARCARTAYCAYMGNATHYTNAARMGNMGNCAR GCNMGNGCNAARYTNGARTCNGARGGNAARATHCCNAARGARMGNCARAARTAYYTNTAY GARTCNMGNCAYMGNCAYGCNYTNAAYMGNACNMGNGGNAAYGGNGGNATHTTYGTNGGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNTTYAARTCNTTYGAYCCNGAYAGYGAYAGYYTNAARGCNAGYYTNGCNTCNATHGGN ATHAARAAYGGNGAYMGNGTNATGGTNYTNGGNAARCCNACNGARGTNCAYAARGGNAGY TCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGAAYGARATHATHCARMGN YTNGAYGAYAAYTTYGARMGNYTNCARGTNGTNGTNTTYGAYGARGAYACNATHYTNAAY AARCCNGTNGARGARTGGCCNATHGTNAAYGGNYTNGTNTCNTTYTTYTCNTAYGGNTTY CCNYTNGARAARGCNATHGCNTAYAARGARYTNMGNAAYCCNTTYGTNGTNAAYGAYYTN GARATGCARMGNACNYTNCARGAYMGNMGNAARGTNTAYGCNATGATGAARGARAAYGAY ATHCCNCAYCCNMGNTAYGCNGTNYTNGAYAARGARAAYGAYCCNGARTGYAARGTNGTN CARACNGARGAYYTNATHGARGTNAAYGGNGTNYTNTTYACNAARCCNTTYGTNGARAAR CCNGTNGAYGCNGARGAYCAYAAYATHTAYATHTAYTTYCCNGTNGCNGCNGGNGGNGGN AGYACNMGNYTNTTYMGNAARATHAARGAYMGNAGYAGYATHTAYTCNMGNTTYTGYMGN GTNMGNACNACNGGNTCNTAYYTNTAYGARGAYTTYATGCCNACNGAYGGNACNGAYGTN AARGTNTAYACNGTNGGNCCNGAYTAYCARCAYGCNGARGCNMGNAARTCNCCNGCNYTN GAYGGNAARGTNGARMGNGAYCCNGARGGNAARGARATHMGNTAYCCNGTNYTNYTNAGY AAYMGNGARAARATGATHGCNMGNAGYGTNTGYAARGTNTTYAARCARAAYGTNTGYGGN TTYGAYYTNYTNMGNGCNAAYGGNCARCAYTAYGTNTGYGAYGTNAAYGGNTTYAGYTTY GTNAARACNTCNAGYAARTAYTAYGAYGAYTGYGCNAARATHYTNGGNACNYTNGTNATG MGNGCNTGYTGYCCNCARYTNCAYATHCCNTAYCCNYTNTGYACNGCNCCNGARGAYATH CCNGTNGTNCARACNACNTCNGGNTCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNACNAAR GCNATHYTNGARAARGARACNACNGCNATGYTNAARGGNTCNYTNGAYGTNATGYTNTCN ------------MGNYTNGCNTGYGGNACNMGNGGNAARTCNGGNAGYGCNAARGGNTCN GCNGAR---TGYTTYCARATHGTNGCNACNGGNATHCCNCAYGCNGTNGAYYTNYTNAAY GARCAYAARGTNGGNGTNGARAARACNCAYGCNAARYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GGNCARCARCCNGGN--- TAYCCNGCNGGNGGN--------------------------------------------- ------------------TAYCCNGCNGGNGGNGTNCCNCCNGCNCARTAY--------- ---------YTNCCNTCNCARTAY---CCNGCNGGNGGNGTNCCNTAYGGNCARGGNGGN GCNCCNTCNGGNCCNTTYCARGCNCCNCCNGGNGGNGCNTAYCCNCARCCN------GGN TAYCCNCCNCARACNGARYTNGAYGAYACNGTNGARACNATGAARCARGTNGARACNGAR MGNGTNGAYYTNTCNCARTTYYTNGAYCARCARMGNGARCARYTNGARMGNYTNGAYAGY GAYAARCARYTNATHGTNAARGARYTNGARTCNGCNATGGCNGARMGNGCNAGYYTNAGY CARGARAARCARAAYYTNTCNCARMGNACNGAYGAYYTNCARAAYCARYTNCARAGYATH GARGARAARACNAARACNGTNCARGARGARCAYGCNTCNGCNGARCAYCARYTNCARGAY AAYGTNGARCARYTNGAYCARYTNGARAGYGARAARTCNGCNATHTCNGARCAYGCNTGY GAYYTNCARTCNACNATHCARGAYYTNATGTCNCARAARGARATGACNGARAARGARYTN AARGARGARATHMGNGCNMGNATHTCNGTNGARGARMGNYTNAARGARGCNGARMGNTCN YTNAARTGYATHGAYCAYGCNGTNCARTCNCARTCNGAYMGNATGGCNTCNGAYGCNAAR GARGARATGGCNGTNAAYGTNMGNAARYTNAARGAYTTYTTYGARGAYYTNGCNGARGAR GCNAARATHTCNTCNGAYAARCCNATHATHATHMGNAAYGGNATGATGGCNMGNAARACN ATGGCNMGNMGNGCNAARACNGTNMGNTAYGARAAYMGNAARMGNTCNACN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AAYGAYCAYTCNGARTCNACNAARTCNMGNMGN TCNAARCCNAAYTAYGGNMGNTTYTAYAAYACNAGYTAYYTNGGNYTNAAYACNGTNTAY AAY------------------------GCNGGNCARAARCARMGNGCNGGNAGYAGYTCN CAYTTYCAYMGNCCNCCNAAYTTYACNTAYTCNAARGAYCCNCCNGGNTTYYTNAARAAR AARGGNACNGGNATGTCNGCNYTNACNTCNGTNACNMGNGTNGTNAARGTNMGNCAYAGY TCNTCNCCNGCNGARYTNMGNAAYCARGARGCNGTNMGNATGAGYATGTTYCCNAGYGCN AARCCNAARYTNCCNGAYGARCCNGAYAARATHGARMGNGAYGAYTGGCCNGGNCCNGCN TCNCCNGCNGCNYTNYTNCCNGARATHYTNMGNCARMGNMGNMGNAGYMGNGGNGARAAR GAYGARGAYGARGAYGARGAYGARGTNAARGARGAYCCNMGNATGAARACNAARYTNGAY GARATHTCNAARATHAARGAYGARAGYGGNATHGGNCARGTNATHTAYMGNGARYTNGAR GGNYTNAARGCNAARCCNCARCARCCNYTNGAYCCNTGGAARGCNTCNMGNGCNCCNAGY GCNAARTTYGARCCNMGNTAYMGNACNMGNTTYCARTCNCCNATGTTYGCNTCNCCNTCN MGNTTYAAYGAYMGNCCNMGNTAYGCNTGGGAYGAYAGYGAYATHMGNACNTAYMGNTCN GCNTCNACNYTNGCNAAYYTNYTNACNCCNAARCCNGGNTAYGGNCCNTCNTAYGTNGCN CCNMGNGCNGCNACNYTNCCNYTNGCNGGNGTNTAYGGNGCNMGNGAYGAYTTYMGNTTY TTYGARTTYGAYGARTCNGAYGAYMGNMGNTCNGCNTAYACNTCNTCNTCNACNYTNACN GGNGARATGGGNTCNMGNMGNCAYGAYTCNTCNTAYGGNGGNTAYGARGGNCCNACNATH CCNYTNYTNCARYTNCARAARAGYACN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYGGNMGNGARACNGAYCAR CCNAGYYTNATGTAYCAYGTNAAYGARACNYTNTTYGAYTTYAARATHGAYAAYTAYACN CCNACNTAYAAYAARTCNMGNTTYGCNYTNGARGCNGTNGTNGTNAGYGARTCNCAYAAY ACNGARATGGCNATHGARACNAARMGNTCNATHGAYGAYGARTAYTCNCCNGGNGTNTTY CARATHACNGAYTGGYTNGCNAAYCCNTCNCARAARTCNAARTCNGGNTTYATGCARTGG AARCCNGTNTGYTAYYTNAARAARGGNMGNAARMGNGCNTCNGCNACNAARGTNGARAAY TAYAARYTNGAYGAYATGAGYGARMGNGARATGGTNAAYGARTCNATHGTNTAYGCNGCN TTYGGNGAYACNATHTGGGAYGGNAARTCNGTNYTNGTNMGNACNGCNAAYATHTCNTTY GGNYTNCCNAARGAYGGNTTYTAYYTNAARAAYAAYTAYACNGTNTGGACNGTNGCNATH GGNTAYGGNACNCCNCCNGARGAYGTNATHTCNAARACNGTNATHATHATHATHTCNTGY GGNYTNGGNYTNCCNGTNATHATHATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AGYCARACNTTYACNTAYAGYTAYCCNTAYGAYYTN GARAGYGTNTGYTTYAARACNCCNATHTGYCARAAYAGY---TCNAAR---------GAY CARTTYTGYYTNYTNGAYGGNTCNCARTCNTCNGCNCARTTYTAYGTNTTYGTNGGNGTN ATHGTNTTYYTNTAYTGYYTNGCNGCNYTNGTNYTNTAYGTNATHTTYGAYGAYTTYTAY MGNMGNAAYAAYMGNGTNATHGTNGCNGAYTTYATHGTNTCNATHGTNYTNACNYTNTTY TGGATHATHGGNTCNTCNGCNTGGGCNGCNGGNYTNTCNGAYGTNAARYTNTAYACNGAY CCNTCNGAYGGNGGNATHTTY---AAYCARYTNGARGARTGYAARCAYCCNCARAAYAAY TGYTTYACNAAYAGYAAYGGNAAYTTYGCNAGYYTNAAYGTNTCNATHATHTTYGGNTTY YTNAAYTTYGTNGTNTGGYTNGGNAAYYTNTGGTTYYTNTAYAARGARACNCCNTGGTTY AARGTNCARGCNAARCCNCCNACN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARGARGAYYTNAGYGTNGCNTGYGGNATHTGYTAYAGYCAYCARYTNGGNGAYCARATH CCNGAYGTNGTNTGYCARTAYCARMGNTGYAGYCARGCNTTYCAYCAYATHTGYYTNTAY GARTGGYTNMGNAAYTCNGCNTGYMGNCARAGYTTYAAYTAYATHTTYGGNGARTGYCCN TTYTGYACNCARCCNATHMGNGTNAARATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATHGCNACNGARGTNCAYGAYMGNGARAARAARAARGCNYTNAARGCNCCNGCNAARCAR YTNGCNAARTCNTCNGCNYTNGCNTCNYTNTCNTCNYTNGGNYTNGGNTAYGGNTCNGAY AGYGARGGNAGYGAYGCNGARAAYGGNCARAGYGARAARGAYGAYTCNGAYTCNGAYYTN GARGARMGNATHMGNMGNAARAARGARGAYTTYGCNAARMGNMGNMGNAAYYTNAGYGAY ACNGARGAYGCNGAYCARAARTCNTCNTCNGGNGAYAARACNAARTCNGARGTNAARATG AARGCNGARAARTCNGARGTNGTNTCNGAYAARTGYACNGAYGTNGAYMGNMGN------ ---MGNAARGAYAGYMGNAGYAGY---------------------GARAARGGNCAYACN GTNGAYGARMGNCCNAARGAYTCNGTNTCNAARGARAARGGNAARAGYMGNTGGGAYTCN AARYTNGGNTCNGAYAGYMGNMGNGARAAR---------------ACNACNGARGAYMGN ACNCARGGNAARAARACNCARAARTCNYTNACNMGNGAY--------------------- ------------------------------------------------------------ ---GGNGCNTCNAARCCNAARATHAARGAYAARCCNACNAARAGYAGYAGYAGYAGYAGY GGNAGYAGYTGYAGYAAYAGYGGNAGYTCNTCNGGNTCNGGNAGYAGYAGYAGYAGYAGY AGYAGYAGYAGYAGYAGYAGYAGYAGYAGYAGYAGYAGYAGYAGYAGYAGYAGYAGY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GAYMGNGTNGAYTAYAARTCNGARGARGAYYTNAARMGNYTNGARCARTCNATHAAY AARCARCCNAAYCARGARATHYTNGAYCAYGARMGNAARMGNAARGTNGARYTNAARTGY ATGGARATGCARGARYTNATGGARGARCARGGNTAYTCNGAYAARGARGTNACNGAYAAR GTNAAYATGTTYMGNAARATGYTNATGGCNAARGARGGNGTNTCNGAY---ACNGTNGTN GARAARGAYGARCAYGGNMGNCCNATHGCNAARGARACNCAYCARYTNGCNGARGCNAAY CAYGCNAARAAYCARMGNYTNAARGARGCNTTYGGNYTNACNGAYTAYGTNGARGGNAGY GCNTTYGAYCCNGARMGNAARGCNAARGARGARCARGCNAARGCNATHGCNYTNGCNCAR AARAARTAYAGYATHGTNCARAGYTCNGAYGARGARGARGGNAARGGNGARAGYYTNCCN CCNCCNAARAARAARAARAARAARTCNMGNCAY---GAYAGYTCNTCNYTNGARMGNAGY AARGARAARMGNAARAARAGYMGNAARCAYAGYAARMGNGAYMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN GCNATHMGNTCNAARGAYAARATGTTYAAYCARTTYTCNTGGTCNGAYATGACNGARGTN GTNTAYGARCARGTNTCNGCNYTNGTNGAYYTNYTNGARACNTCNGAYGARAARYTNAAR MGNAGYAAYAAYTCNGCNMGNGAYMGNGAYTAYGCNTAYTCNTCNYTNAARCARGAYCAY GARGARCARATHAGYAARYTNACNAAYATGGCNMGNGARMGNGARGCNYTNTGGCARMGN CARAARGARGARYTNGARCARCAYTAYAAYGARYTNYTNTCNGAYYTNCARAAYMGNACN AARAARACNCARGCNATHGCNGAYCARGCNTGGGARAARYTNMGNGCNACNGGNAGYGTN CARCARGGNYTNGARACNGARGTNGTNGARYTNMGNMGNGARYTNGCNGARTCNCARGTN CARGCNTCNTCNYTNYTNTCNGCNTGYGCNYTNYTNTCNGGNGCNYTNTAYCCNYTNTAY ATGAARGCNTCNAGYYTNTCNAGYGARTGYCAYATHYTNGAYGAYYTNTTYTGYACNTGG GARACNTGYAARGARMGNGCNATHTAYYTNAGYGCNGTNYTNAGYTCNGGNAARGAYAGY GARCARGAYCARCCNGARMGNGAYAGYMGNTTYCARMGNAARGTNAGYCCNATHYTNMGN TTYMGNGTNGGNGTNATHGCNGTNYTNGCNGCNAAYMGNYTNGCNTTYYTNGGNGCNGGN TGYGTNMGNTGYTTYGTNTCNTAYAGYTCNAAYGTNGAYTCNAGYGGNYTNCARGTNTCN ACNGGNGGNYTNGCNMGNGCNGARAARGTNMGNGCNGTNAAYYTNAGYCAYCARGARCCN CARGAYGARTCNGGNTTYGGNCCNGCNTCNGARCARGGNYTNAGYTCNTGGYTNAARAGY ACNGAYYTNYTNGARGTNGTNATHGGNTCNATGACNGARYTNCARGAYTCNYTNMGNGTN ATHAARGAYTCNAARAGYMGNACNGARGTNAARYTNGTNGTNACNGCNGCNMGNTCNGGN TTYACNAARYTNATHGAYMGNYTNTCNTAYTTYTTYCCNTCNTCNACNYTNCCNATHCAY TCNTCNATGMGNGARMGNTCNTCNYTNYTNMGNAARYTNGARMGNCAYYTNTCNTCNATH GTNAAYAAYACNCCNCARCAYYTNAARGGNAGYYTNATHTCNTCNCARGARGTNATGAGY AAYYTNCARAGYCAYGTNYTNGAYYTNACNCARMGNYTNCAYTCNGCNGARAARGARMGN MGNTAYYTNYTNTCNGAYTTYAAYGAYYTNAARCARCARATHGGNGAYGARAAYAAYTCN YTNCCNCAYACNAGYGARAARTCNTCNTCNGTNAARGGNACNAARTAYGTNGCNATGGAR AARTTYGARAARGTNTGYGTNGARYTNAGYAGYGCNYTNMGNMGNGARCARAARGCNCAR GTNYTNYTNCARGARCARAGYAGYCARYTNACNCARYTNACNTCNMGNYTNGAYGTNTGY GTNTCNGARGARATGAARATGCARGARCAYYTNGTNCAYAAYGGNAARAGYYTNACNGAY YTNMGNCARCARYTNMGNCAYAARAAYCARAGYYTNMGNCARATHGARAARCARATHGGN CAYTCNGARCAYGAYAARGARTCNYTNTCNAGYAAYYTNAARGAYGCNGARAAYGCNYTN MGNACNGTNGCNMGNGAYAARGGNGTNYTNGCNCARTAYACNAARAGYGTNGARGGNGCN YTNGARATHGCNAARAARCARTTYYTNATHYTNTGYGARCCNGCNCCNYTNTCNGARGAY GTNTCNYTNTCNMGNYTNYTNYTNAAYGCNGARYTNATHCCNCAYGAYATHGGNAARGCN GGNCCNGARYTNATHGCNGTNCARAAYYTNGTNGGNGGNTTYGTNGAYGCNCARCAYCAR GCNGTNAARAARATHMGNTCNYTNGARGARGARATHATGTCNCAYMGNGAYCAYATHGAY ACNYTNAARMGNGARYTNAGYAAYGCNGTNCARMGNGARTTYAAYGARAARGTNGARAAY GCNACNGAYGGNGCNTTYTCNYTNYTNCCNGAYGAYAGYGAYATHTTYYTNCCNYTNAAR GARGAYTCNGAYGTNTCNTTYGARAGYYTNCCNTCN------------CCNTCNAARCCN TCNTCNTGGGGNGTNCCNTCNGTNAARCCNAGYAARAARTCNGCNTTYCAYTCNGTNAAR TCNAAYACN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYCCNTTYGCNGARGCNGAYATHATHCAYGAYCCNGCNGARTAYTAY---AAY GTNTAYTCNATGATHAAYAAYTTYGAYTCNCAYTGGATGGARYTNGARTCNAGYGTNCAY CAYGARACNYTNTCNMGNAGYCAYMGNGTNGCNGCNGTNATHCCNYTNAARTTYCARTTY CCNTTYTAYGGNCAYCCNATHGGNAAYATHACNATHGCNACNGGNGGNTTYATHTAYATG AGYCCNTTYYTNCAYCARTGGYTNACNGCNACNCARTAYGTNGCNCCNYTNATGGCNAAY TTYGAYCCNTCNYTNAAYACNAAYTCNAGYATHTAYTAYCARAGYCARGAYGAYCAYTTY ATHATHGARTGGAARGAYGTNYTNYTNCARGAYCARAAYACNACNGGNATGTTYCAYTTY CARGCNATHYTNAAYCARACNGGNGARATHAARTTYGTNTAYAARAARGTNCCNATHCCN GTNAAYGGNATHTCNACNAGYMGNCAYCCNGTNAARATHGGNYTNTCNGAYGCNTAYTAY GTNGAYACNTAYYTNCCNMGNTTYCAYATHAARMGNMGNACNATHTAYGARTAYCAYAAR GTNTCNGTNAARATGAAYGTNGTNMGNTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GARAGYGCNGARYTNGCNAARTTYTGGAGYGAYACNGTNAAYAGYAAR CCNAGYTGYATGCARCCNYTNCAYAAYAARAAYGTNAARATGYTNAAYYTNTAYTGYCCN ATGAGYGGNATHGAYCARGARGTNAGYTAYTCNYTNTTYMGNATGTTYGAYTGGCCNYTN ATHGCNGGNGGNTTYGTNAAYGARAARTGYYTNMGNGAYTCNCARGGNYTNTTYCAYACN ACNGARMGNTCNTGYATHGTNTCNGGNYTNGCNATHTGYGGNGARGARGTNCARGTNGCN TCNGTNYTNATHMGNAGYGAYATHGAYTCNGARAARGARGTNGARGARATHATGCARMGN YTNAARGAYTTYGGNYTNCCNAARAAYAARACNTTYGGNYTNATGTAYGCNTGYGTNGGN MGNGGNTTYCAYATHTAYAAYAARCAYAAYGTNGARTCNCARATHTTYMGNAARCAYTTY CCNMGNATHCCNYTNTTYGGNTTYTTYGGNAAYGGNGARATHGGNTGYGTNTAYCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNMGN ACNYTNGCNCARYTNGGNACNCARYTNGGNGTNAARGAYGCNTCNGAYACNAGYTTYATG YTNTCNYTNCARAAYYTNCAYAARGARGCNTAYGAYGTNAARGARCARYTNGCNAARGAR AGYGARGARYTNCARYTNYTNACNMGNMGNTTYYTNACNGCNTCNGTNAARTAYAGYTCN YTNCARMGNGCNACNGARGCNGTNAARATHAARACNGARTCNGAYAARCAYYTNAAYTCN AARMGNAARGARGAYATHGCNTTYYTNYTNGGNAARTCNAARTAYTAYGCNAARGARATG GCNAARYTNCARGGNCARYTNGCNAARTCNGGNGTNGAYAARTCNGTNTTYCAYAAYAGY YTNYTNAARAARGAYGARGTNYTNYTNAAYYTNAARAARGARYTNGARCCNYTNCARCAR GARYTNCARTCNTAYTCNACNYTNCCNCCNGAYYTNGTNGARGCNAARATHAARATHGAR CARYTNAARMGNGARYTNACNGARYTNGARAARCARATGTCNGARTGYGTNGAYGCNATH MGNACN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARGAYGCNYTNATHTGYTCNTTYGCNACNCCNTAYAAYAAYGAR GAYTAYGGNGARNNNGARGGNGARGGNGCNAGYGARCCNGTNCARCCNACNGAYATHGAY GAYGAYAARAARGAYGGNGAYAARAARAARAARAARAARAARAARAARAARTGGYTNTCN ATHTGYYTNACNAAYTGYAARTAYGAYGTN------------------------------ ------------------------------------------------------------ ---------------------------NNNAARATHAAYCAYTTYCCNGGNATGAAYGAR ATHTGYMGNNNNGAYATGYTNGCNMGNAAYYTNAAYMGNATGCARAARATGTTYCCNAAR GARTAYAAYGTNTTYCCNAARACNTGGTGYYTNCCNGCNGAYTAYGGNGAYTTYCARGCN TAYAAYMGNCARAARAARAAYAARACNTAYATHYTNAARCCNGARTCNGGNTGYCARGGN MGNGGNATHTGGGTNACNAARAGYCCNAARGARATHAARCCNCAYGARCAYATGATHTGY CARGTNTAYYTNAAYAARCCNTTYYTNATHGAYGGNTTYAARTTYGAYYTNMGNATHTAY ACNYTNGTNACNTCNTGYGAYCCNYTNMGNATHTTYGTNTTYAARGAYGGNYTNGCNMGN TTYGCNACNAAYAARTAYTGYGARCCNAGYCAYAAYAAYACNGAYAAYGTNTTYATGCAY YTNACNAAYTAYGCNATHAAYAARCAYAGYGAYGAYTTYATHMGNGAYGAYGARGCNGGN AGYAARMGNMGNATHAGYACNATHAAYAARTAYYTNCARGARAARGGNTAYGAYGTNGAY MGNYTNTGGTCNGAYATHGAYGAYGTNATHATHAARACNYTNATHTCNGCNCAYTCNGTN YTNMGNCAYAAYTAYMGNTCNTGYTTYCCNAAYCAYYTNAARGGNTCNGCNTGYTTYGAR ATHYTNGGNATHGAYGTNYTNYTNGAYAARAARYTNAARCCNAGYATHYTNGARGTNAAY CAYTCNCCNAGYTTYGCNACNGAYGCNACNYTNGAYMGNGARATHAARGGNACNYTNATH TAYGAYACNYTNMGNYTNATHAAYTTYGGNGCNGTNGAYMGNMGNAARTGYYTNGARGAR GARMGNMGNMGNATHAARGAYMGNYTNYTNGGNAARTAYGTNAARAARGARACNAARGAR GARYTNGARGCNGCNCARTGYCARTAYGTNGARCARYTNGARMGNTAYGARAAYACNCAY ATGGGNAAYTTYMGNMGNGTNTAYCCNATHCCNGGNTCNGARAARTAYGAYAARTTYTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNGTNMGNMGNGTNGTNGGNGGNGARGAR YTNACNATGGGNGCNTGGCCNTGGYTNGTNTCNYTNAAYTAYATGGARCAYCAYGCNTAY ATGGARYTNCARGGNYTNCCNCAYYTNTGYGGNGCNACNYTNATHAAYTCNCARTGGATH ATHACNGCNGCNCAYTGYGTNCAYCAYCAYTCNGGNAGYCCNGGNYTNGGNGAYCCNTCN AAYTGGAARGCNGTNYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TGYAGYMGNGCNAARCCNTTYMGNATHYTNATHATGGGNYTNGAY TGYGCNGGNAARACNACNYTNYTNTAYCARYTNAARYTNGGNGARGTNGTNACNACNATH CCNACNATHGGNATHAAYATHGARACNGTN---ACNGCNGGNTCNGTNGARATGGTNTGY TGGGAYGTNGGNGGNMGNGAYAARATGMGNGCNYTNTAYMGNCAYTAYTAYCARGGNACN AAYGGNTTYGTNTAYATHATHGAYTGYACNGAYMGNGARMGNYTNGAYGARGCNYTNTAY GARYTNTGYAARTAYGTNYTNGARGARGARGARACNMGNGAYAGYGTNATGATGGTNYTN GCNAAYAARCARGAYGTNGARAARGCNATHGGNGTNAARGARGTNGARGARAARATHCAR GARAARTGYACNATHAARGAYGGNMGNTCNATGTTYGTNATGCCNTGYAGYGCNGTNACN MGNGAR------GGNYTNAGYGARGCNTTYCARGTNTTYGCNCARCARATGAARMGNAAR CARGCNGGN---------------------GGNGCNGCNTCNGCNYTNGAYGAYAARCAR AARGAYGTNGCNCARGCNAARYTNAGYTTYYTNCAYAAYTTYAARACNGAYCCNTTYCAY TTYGTNAARTCNATHYTNTTYTAYTAYTGYCAYAGYTGYTGYCARTTYAARAARGGNTGY TGYGTNGAYCAYGTNYTNCARCAYYTNMGNYTNCARATHTGGAAYATGTGGTAYTTYTGG TTYYTNATHATHTTYATGATGATGTCNTGYTTYGGNGGNTGYGGNTAYTAYMGNMGNMGN MGNYTNGCNATH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATHCCNGGN TTYCAYGTNGGNATHATHGCNCAYGGNGAYTAYTGYGAYGTNGARCAYTTYTAYGAYATH AARTCNYTNGAYYTNACNGAYTCNGTNGCNGAYGTNGTNACNTTYGTNCARCAYACNGAR GGNACNGGNGGNGGNGAYATHCCNGARTGYTAYGARYTNGCNYTNTAYCAYGCNAAYAAR ATGTCNTGGACNCCNAAYAGYMGNMGNATHYTNGTNATHATHGGNGAYTCNTAYCCNCAY GARCCNGAYTAYCCNYTNAAYTCNYTNMGNYTNAAYTGGMGNACNGARYTNACNAAYYTN ACNGARAARGGNGTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TCNCCNACNAARGAYYTNGCNACNGCNGGN--- GTNGARACNCARCARTGYAAYATHTGYYTNACNGAYTAYGARGCNGGNGAYACNAARMGN YTNATGCCNTGYAARCAYGAYTTYCAYAARGAYTGYATHGAYCARYTNYTNAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARTCNTGYMGNYTNTGYCARGARGARAGYCAYATHCCNYTNAARTGYAAYGAR GTNGARACNAARACNAGYMGNAAYATGMGNACNTAYATHGARAAYGARATHGCNGARGCN GTNATGMGNAARTGYCAYCAYTGYGGNAARMGNTTYGTNAARGAYTAYGGNTGYAAYAAR ATGACNTGYATGTGYGGNGCNACNAGYTGYTAYYTNTGYAARGARCCNGAYATHGGNTAY GARCAYTTYGAYGAYAAYAARAARTGYGCNTTYACNAGYCCNAAYGCNATHCAYAARMGN GAYATGAARGCNGCNGCNGTNMGNGCNAARGCNAARTAYATHAGYGAYCAYCCNGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MGN AARACNTGYATHMGNAARGGNGAYATHAGYACNGCNAGYCCNTGYCCNATHTGYMGNGAY GARTAYYTNGTNYTNGAYGCNACNAAYGTNAARYTNYTNGARCARTTYATHTCNCCNCAY TCNGGNGARATHTTYGAYTCNMGNAARACNGGNYTNTGYCARACNCARCAYAARAARYTN ATHGTNGARGTNATGAARGCNTGGGAYCARGGN--------------------------- ---------------------------TCNCARGTNYTNCARTGYTCNATGGAYAARGAR YTNAAYYTNTAYTGYGAYATGAARGARCARATHAAYCCNGTNGCNAGYYTNGTNGTNTTY GGNYTNACNAGYCARCCNGTNGAYCAYGARATGAAYGGNCAYMGNAARCAYGCNTCNTCN GAYGCNGAYMGNTCNCCNGAYGTNGAYAAYGAYTCNGAYGAYGAYGAYGAYGGNGARTTY AAYGAYTAYTCNTCNAAYGAYGAYATGAGYGAYAGYGARCCNACNATGACNGARGCNMGN AGYMGNCARMGNAARCAYAGYMGNACNAARGCNCAYCARGGNATHACNCARGGNAAYATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGAYGTNAAYCCN TTYCCNGAYGCNYTNGTNACNGAYTGGTCNTTYYTNAARTCNTGYTCNTCNMGNAAYAAR TGYCCNCARTGYAARMGNTCNMGNAARTAYTAYTGYTAYACNTGYAAYGTNGCNYTNCCN CAYATHGARCARAARYTNCCNCAYGTNAARYTNCCNGTNAARGTNGAYATHATHAARCAY CCNAARGARATHGAYGGNAARAGYACNACNCCNCAYGCNGCNATHYTNGCNCCNGAYAAR ------------------------------------------------GTNYTNYTNATH TTYCCNGGNGARGARTCNGTNACNYTNGCNGARYTNGCNACNAARGTNAARGGNGAYATG AAYTAYTCNCAYTCNYTNGARGARGCNGARAARAARTAYGAYATHGAYACNGARAAYAAY CARTGYGGNGGNACNACNGAYAGYCAYAGYGTNCCNGTNYTNCAY--------------- AARCCNGAYGTNGARGTNCAYAAYGTNACNGARACNGARYTNCAYAGYTTYTCNTCNTCN GARAAY---AARACNCAYGARGTNCARGARCCNAAYYTNAARATHACNCAYAARMGNCCN TAYAGYTCNATHAGYATGCCNCARATGTCNACNGARTCNMGNAAR--------------- ---AGYYTNCCNAARCARATHAAR---------GCNGARATHCCNTTYGAYMGNGTNGTN TTYATHGAYTCNACNTGGAAYCARACN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GGNGARYTNGARAAYMGNTAYGGNATHCCNCARCAY TTYGGNYTNTTYTAYACNATGGGNTTYGCNYTNATHATGGARGGNATHATGAGYGGNAGY TAYCAYGTNTGYCCNAAYTAYAGYAAYTTYCARTTYGAYACNTCNTTYATGTAYATHATH GCNTGYYTNTGYATGYTNAARATHTAYCARTTYMGNCAYCCNGAYATHAAYGCNAARGCN TAYACNGCNTAYTTYTCNATGGCNYTNATHATHYTNGTNGCNGTNYTNGGNGTNGTNTAY GGNACNAAYATHTTYTGGGTNTTYTAYGCNYTNGCNCAYATGYTNGCNGCNTTYATHYTN TCNGCNCARATHTAYTTYATGGGNMGNTGGAARYTNGAYMGNCAYATHTTYAARMGNYTN YTNYTNTAYGTNATHTCNGAYYTNAARCAYTGYMGNMGNCCNGTNTAYGTNAAYMGNTTY GTNYTNYTNTTYTTYGGNAAYGTNATHAAYTGGGCNTTYGCNYTNTAYGGNGCNATHMGN CARCCNTCNGAYTTYGCNAGYTAYYTNYTNGCNATHTTYATHGGNAAYYTNYTNYTNTAY ACNATHTTYTAYGTNATHATGAARYTNYTNAAYAARGARMGNYTNAAYTGGYTNGTNGTN YTNATHATHYTNGTNACNAGYATGACNTGGGCNGGNGCNYTNTAYTTYTTYTTYCARCAY YTNACNTCNTGGTCNGARACNCCNGCNGGNTCNMGNGARGGNAAYMGNAGYTGYATHYTN YTNTCNTTYTAYGAYGCNCAYGAYGTNTGGCAYTTYYTNTCNGCNATH------------ ------NNNGTNYTNYTNATGYTNGAYGAYGAYYTNAGYYTNGTNMGNMGNGAYMGNATH CCNGTNTTY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TTYAGYGGNTAYATHCCNGTNGAYGARYTNGARATH AARACNAGYMGNAGYAGYGGNCCNGGNGGNCARAAYGTNAAYAARGTNAAYAGYAARGTN GARGTNMGNTTYCAYYTNGAYTCNGCNTCNTGGATHCCNGAYTGGATHAARCCNMGNATH GCNGARCARGARCARAAYMGNATHACNAARGARGGNTTYYTNATHGTNMGNTCNGAYATG ACNMGNAARCARATGYTNAAYCARGCNGAYTGYATGAAYAARYTNMGNAAYATHGTNTAY GGNGTNTCNGTNYTNCCNMGNGARCCNACNAARGARGARYTNGARYTNAARGARMGNMGN ATHGTNAARGCNAARGCNGGNGTNYTNMGNGARAARAARAARMGNTCNYTNYTNAARAAR TCNMGNTCNACNCCNGAR------TCNCARGCNATHAAYCARYTNMGNTAYAAYCCNTAY MGNAARGCNTCNYTNGTNTCNGCNGCNGCNAAYGGNGTNATHTCNYTNTGGGAYACNAAY ACNMGNGGNCAYGTNCAYTCNTTYGCNTCNGGNCAYCARGCNCCNGCNTCNGAYYTNGCN TTYTCNCCNGTNAAYGAYTAYYTNATGYTNAGYGTNGGNYTNGAYAARMGNYTNGTNTTY TAYGAYYTNCARAAYMGNGAYTCNATHAARACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TTYAARAAYATHCCN YTNAAYCCNTAYGARATHGARATHMGNAARYTNCARGAYGTNTCNCARCARATGAARATH CARCARACNATHGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MGNTGYYTN CARTCNYTNACNMGNTCNGTNCARCARATHMGNACNGTNYTNCAYGAYAGYTCNGTNTGG MGNCCNYTNYTNGARAARGTNMGNTCNACNAAYCARGARATHATG--------------- GTNYTNGCNATGACNTGYYTNTGYAAYYTNATGYTNGARTTYAGYCCNAGYAARGARGCN YTNTCNCARTAYAAYGCNGTNGAYATHYTNTGYGARYTNTGYCAYAGYGAYGAYAAYATH GTNMGNYTNAAYGCNATHTGGGCNGTNATGTCNATGTCNTAYTGYAGYCCNGARGARYTN MGNGCNACNATHATHAAYAAYYTNGGNTCNGAYACNATHGTNAARMGNATHGARGAYCCN GTNCCNYTNATHMGNGARAARGTNYTNGCNATHGTNMGNAAYYTNYTNACNAAYAARCCN AGYATHGAYAAYACNGTNAARYTNYTNGGNAAYCAYGTNATHGAYGCNATHTTYMGNATH GTNAARGAYAAYAAYATGCCNYTNAGYGTNACNGARCARGCNYTNTGYGCNYTNAGYAAY ATGGCNGAYGGNCCNTCNTGYAARGCNTAYATHATHGGNAARATHGAYGARATHAAYTCN GTNGTNAARTTYYTNCARTAYCCNGARCCNMGNYTNCARYTNCCNGCNATHCARTTYGTN AGYAAYYTNGTNGAYACNAGYGAYGAYGAYYTNGGNCCNTTYCCNGGNGCNGGNTCNTAY CARMGNATGYTNGARYTNAARACNYTNGGNGTNCARACNYTNYTNGAYAGYYTNGTNGGN ACNACNGTNGARGAYGTNGAYAARMGNGCNAARGAYGCNYTNAARTTYTTYGCNATGTCN ACNTAYATHMGNMGNTAYGCNAARTAYYTNAAYGARAARGCNGTNTCNTAYMGNTCNATG GCNTTYGAYTTYTGYAARGTNAARMGNGGNAARGAYGAYGGNYTNYTNMGNACNATGAAY ACNGARAARYTNYTNAARACNYTNCCNGTNYTNCARCARCARYTNGAYGCNYTNYTNGAR TTYGAYTGYACNCCNAAYGARYTNACNAAYGGNGTNATHACNGCNTGYTTYATGYTNYTN TTYAARGAYYTNATHMGNYTNTTYGCNTGYTAYAAYGAYGGNATHATHAAYYTNYTNGAR AARTAYTTYGAYATGAAYAARAARCARTGYAARGAYGCNYTNGARYTNTAYAARAARTTY YTNGTNMGNATGGAYAARGTNTCNGARTTYYTNAARGTNGCNGARAAYATGGGNATHGAY AARGGNGAYATHCCNGAYYTNGCNAARGCNCCNGCNAGYYTNYTNGAYGCNYTNGARCAR CAYYTNGCNTCNYTNGARGGNAARAARGGNGTNGCNACNACNCCNACNGGNTCNGCNAAR CCNGCNAGYTTYACNTCNGCNYTNAAYAGYATGTCNACNAAYACNTTYGAYGTNACNGAY GCNGARAARAARMGNATHYTNGARGARGARACNCARCARYTNCARAARYTNAARGCNTTY AGYCCNCARGAYCARAARYTNAARGARAGYTCNTCNCCNYTNAARCCNCCNGCN---CCN ATHAGYAGYCCNTTYGCNGCNGAYTCNGCNGCNACNCCNAGYGCNTCNGCNTAYYTNTTY GGN------------------GAYACNACNATHMGNCCNAGYGAYGAYYTNYTNAGYYTN TCNGGNAAYCCNTTYATGGGNAAYGTNCARAAYGCNATGGCNACNGGNTTYACNGCNCCN CCNCARCCNGCNTCNAGYAAYCCNTTYCCNGCNGCNGGNTTYCARGCNAAYGGNTAY--- ------TCNAAYACNTTYACNTCNGARGCNGAYTTYGCNAARGCNTTYAGYAAYGGNGGN ACNAAYAAYATHCARGCNGCNTCNGGN--------------------------------- ---------TTYGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ACN ACNYTNACNATGGCNCCNGTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CCNGGNYTNAAR TGGYTNGAYGARGAYAAYAARATHTTYTGYATHCCNTGGMGNCAYCAYAGYAAYCARAAR TGGGAYGARAARGAYTCNCARATHTTYAARGARTGGGCNATHGTNTCNAAYAARTTYAAR GAYGGNGAYCARGARTCNTGGCCNGARTGGAARACNMGNATGMGNACNGCNYTNACNAAR YTNAAYGAYGTNGARGARATGAARGAYTGGCAYAAYYTNAAYGAYCCNAAYCCNTAYAAR GCNTAYMGNTTY---ATGGCNACNYTNCCNAARTCNGCNATHACNGCNGAYTGYGAYGTN AAYYTNGAYTTYYTNACNAARGGNGARMGNGARGCNYTNYTNTCNAARAARATGGAYATG ATHMGNGARMGNAAYMGNGCNATHAGYGARMGNCAYCARATGATHCARGCNGAYAARYTN AARGCNGARGARAGYGTNATHACNATHAARGCNYTNGAYAGYAARAAYYTNYTNGCNGAR GGNGCNTCN---ATHAARAGYMGNGGNMGNGGNMGNGGNCARCAYTCN------------ CARAARGAYGGNAAYAARCCNCARMGNGARMGNCCNAARTCNTTYMGNGAYGCNTCNTTY TAYGARCCNATHATGGAYGTNTGYGAYYTNAAYAAYCAYMGNATGGARGTNAARGGNMGN GGNCAYGGNGGNTAYNNNNNNCAYNNNNNNCAN------------------NNNNNNNNN NNNGCNGCNACNACNCCNAARAAYMGNMGNAARYTNCARCCNAARGARGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AGYTTYCAYTCNGGNCAYCCNCAYTCNAAYMGNCARCAY ------------------------------------------AARGCNACNTAYGAYGGN MGNYTNAARGGNGAYAGYGGNCCNCCNCCNGAYCCNTCNTTYAAYCCNYTNGCNGAYMGN MGNMGN---------GCNTCNGARAARAARGAR------------GCNYTNCARCARGAY CAYAARMGNCAYCCNMGNAAYTAYGGNGGNGGNGCNGAYYTNTCNMGNGTNAARGARACN ATGAARACNATGMGNGARAARGARAARGARMGNCCNGCNACNGGNAARCCNYTNGARATG GTNATGACNGGNAARGARMGNMGNAAYCAYCARGAYTGGAARCARGARMGNGARMGNTAY GAYAARGARMGNGTNCARMGNCARATGAAYGARGGNGGNAAYTGGMGNMGNGARTGGGAY AAYGAYAARGTNGTNYTNGARTAYGAYGARACNCCNCAY------------GCNGARCCN GCNAARMGNCCNGCNGGNMGNATHGGNAGYGGNMGNTTYGAYMGNGGNGARMGNGAYGAY MGNTCNMGNGGNGCNGCNAAR---------GGNGGN------------------------ ---------------------------------------------------------YTN CAR---CARCARCCNAAYCAYGCNCARCCNYTNYTNCARTCNCCN---CCNCCN------ ACNCCNCARCCNGGNGARGGNAARGTNCCNMGNGGNMGNGGNMGNGGNMGNGGNMGNGGN MGNGGNMGNAGY------AGYGGNGGNGGNGCNCCNGGN---GAYAARTAYCCNMGNCCN MGNACNTGGTCNGGNGGNGAYGAYMGNTTYGTNGARTGYCARAARGARATGYTNYTNGTN AARTTYGARAAYACNGCNGGNGAYAAYTCNGTNGARGTNGARTAYGARAAYGARGARCCN ATGTCNCAYCCNACNAARCCN---GCNCCNGCNACNATHCCNGGNMGNGGNCCNACNGGN MGNACNCARAAYCAYAAYTCNAARCARMGNGGNGGNGGNGARGGNGGNGGNAARCARCAR AAYCARAAYAAYGGNGGNCARAARGGNTCNCARCARCAYCAYCCNCCNCARGGNAGYCAY CAR---------------GAYTGGGAYGGNGTNGCNGCNAAYACNGGNYTNCCNCAYTCN GCNTCNGARGARTTYMGNGTNMGNACNTCNTCNCAYTCNCARAGYTAYGGNGAYAGYGAR GARTGGGARGAYTGYACNCARTCNTCNGGNGTNCCNGARGARGAYGAY------------ GAYGAYCAYGARCARCARYTNMGNYTNGARTGYCARYTNAAYCCNGARGCNCCNGARTTY YTNCCNACNTCNCCNGAYTTYYTNAARACNCCNCCNGGNCAYGTNAARGTNYTNAAYTGG GCNGCNACNAGYAGYAGYCCNACNTCNCCNTGYTCNACNGTNAGYYTNGCNTCNGTNAAY ---TCNCCNCCNCCNACNTCNYTNTTYGTNCCNAARTCNCAR---------TCNGCNGAY GCNATHTCNTCNAAYTCNTCNCCNTCNTCNCCNGGNTCNTCNGCNTCNACNMGNGCNAAR AARMGNMGNGARGARAGYGAYGTNATGCCNGARGCNGAYGARCCNYTNCCNCCNCCNTTY YTNYTN------------------------------------------------------ ------------------------------------------------------------ ---------------------------CAYTCNAGYMGNAARGTNTCNTCNTGYMGNCCN GCNAARGARCAYACNTTYYTNACNGAYGTNGCNGAYGTNMGNACNATGGARCAYGGNYTN YTNACNYTNYTNGAYAAYTTYCAYTCNGGNAARYTNCARGCNTTYGGNAGYCAYGCNACN TTYAGYAARATGGAYGCNATHMGNATHCARCARGARCARYTNGCNAARCARCARTTYGAR ATGGAYYTNCCNCCNMGNGCNGCNGCNAAYMGNATGAAYTCNGARGARGCNMGNAARGAR AGYAGYGARAARATGGAYACNYTNATHCAYCAR--------------------------- ------------------------------------------------------------ ---------------------------------MGNGARAARCCNGAYCCNAARGAYTAY YTNCCNGARGTNGTNGAYAARGARGTNCCNCCNGGNGTNTCNTTYYTNCCNGAYGTNCAR MGNGTNACNYTNYTNACNAAYYTNAARTTYTAYTTYYTNTCNGCNGTNCARTTYAAYAAR ACNAAYATGGCNGTNTCNACNGCNGGNGGNYTNCCNATHYTNYTNGARGAYGGNACNGAR GARGAYGCNGARGCNATGGCNGTNGAYGGNACNATHGTNGTNTCNGTNTCNMGNGARGTN YTNTCNAGYYTNAGYACNAAYTGYCARAARTTYGTNMGNACNGTNTGYAAYGTNYTNAAR MGNACNAAYYTNMGNATGGTNACNGAYCCNGARATHGGNTGGGCNATHYTNACNTGYAAY ACNGAYGAYTTYTGYAAYCCNAARTCNGCNATH--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYGCNACNGGNCCNMGNCCNGARCCNGTNTAYYTNMGNMGNGAR AARCARCARCCNCCNTCNYTNGTNGCNACNAARMGNCCNCAYGGNAAYAGYCCNTCNACN YTNACNCAYCCNCAYACNGTNCARGCNMGNTCNYTNMGNTAYGGNAAYGAYAAYAGYAGY GTNAAYMGNCARTCNMGNACNCARAGYACNMGNCCNGAYCCNATHCCNGGNCARCCNTAY GCNGGNGCNCCNGCNCARCARYTNGGNAGYGCNCCNYTNMGNAARGTNGGNMGNTCNCAR CCNYTNACNATHCAYGGNAAYGGNACNTTYGCNAAYAARCCNAGYYTNATHGGNGARACN ---------AGYGAYTGYCCNAGYCCNTTYATGAARCCNCAYTCNMGNTTYGARTCNGGN YTNGARCARGTNCAYTCNCARCAYCAYCCNGAYTTYYTNCCNCCNATGCCNMGNCCNCCN CAYACNTCNGTNGGNGAYGAYAGYATHYTNGARCCNAGYCAYCARATGACNAAYGTNCAR GAYYTNGARMGNCARTTYCARGARYTNTCNATGCCNCAYGCNCCNGGNMGNCCNGAYATG GGNCAYCARTCNAARAARYTNTGGGAYGAYGAYCCNCAYAARGTNGGNGAYAGYCARTCN AARGGNATHTTYCAYCAYGGNTGGACNACNMGNGAYGAYACNTGGACNAGYGGNGCNACN GARAGYAGYAAYCARATHGGNGTNAAYATGGTNGAR---TAYGTNYTNGGNGGNTCNCCN AAYAARYTNGARCCNGGNGCNYTNAGYMGNATHAARCCNTTYGARGARAARAARAGYAAR ACNCCNTCNCCNTTYGARGARGGNGGNGAYGARGGNAARGAYTCNYTNCARGCNAAYGGN ATGATGTCNAAYGGNYTNGAYGAYGGNGGNTTYMGNGGNAGYMGNCARACNTCNCCNGCN GAYGARGARMGNCARGGNGTNGTNGGNATGCCNATGGAYCCNCARAARYTNCAYYTNMGN GAYGGNGGNGAYTTYYTNGAYAAYGGNCAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGAGYGCN TCNGTNGGNACNATGMGNGCNGGNTCNAAYAARCAYACNGGNCCNAARGARAARACNGGN AARGGNGAYAARAAYACNTCNTCNCARCARTCNACNGGNGTNAARAGYGAYACNATGTCN AAYAARATGCARCCNACNCARGARCARYTNMGNYTNGCNCARATHATGAAYACNGGNCAR TCNGARGCNGAYCCNGAYACNGTNAARGARYTNATGGARATGACNGGNAARAGYGARGAY GTNGTNGTNATHGCNYTNCAYGAYTCNGARAAYGAYGCNCAYMGNGCNGTNATGYTNYTN YTNGARGGNGGNAAYGARCARGGNGARTGGMGNGARCARGGNGGNAARMGNAARAARAAR ACNGCNTCNCARAARGAYGGNTTYAAYCAYGTNGGNGAYGARAAYGGNGARGGNMGNAAY AARGARAAYMGNGAYGARMGNGAYAARGARGCNGGNTCNGAYMGNCARGAYATGCCNCCN MGNMGNGGNMGNMGNAAYAAYGGNCCNCCNCCNMGNATGGCNMGNGGNMGNGGNMGNGAY MGNGTNACNGGNGGNGAYMGNGAY------MGNGARMGNAAYAGYAAYGARGAYTGGGAY AAYGARMGNGARGAY------AARTCNGCNMGNGGNGAYAARGARMGNGGNGGNGGNGAY MGNGGNMGNGCNMGNGGNMGNGGNGGNYTNGGN------MGNMGNTCNGGN--------- GGNGGNMGNGGNGGNMGNTTYAAYAAYAGYAGYGAYMGNGAYAAYMGNGGNTTYAAYMGN GTNCCNMGNTTYGAYAARATHAAYAAYTCNCARCCNYTNGAYGGN------CCNGARATH GAYACNTGGACNAAYGARACNGCNGTNACNAAY---ACNAGYAARGAYACNGAYTGGGAY AAYTGGAAYGAYTCNATHGTNAAYGARGAYGAYCARTGGACNGGNACN------GARACN AARGTNTTYACNTCNTCNCARACNAAYATGCCNCARGCNGARCCNGTNGGNGGNGAYCCN CCNAGYTCNYTNGGNCARMGNYTNGAYGTNGAYAGYYTNTTYGARTCNGCNAARTTYCCN AARGCNCCNGAYTAYTCNAARCCNTGYGGNGAYGCNTAYATHACNCARTTYAAYCARGCN GCNACNGARTCNATHAARAAYACNATHGGNATHGGNTCNTCNTCNMGNCARCCNATHGGN ATGTCN---------------CARCCNTCNTCNTCNATHCCNYTNGGNYTNTCNAAYYTN GGNCARAAYTCNAAYCARATGCAR---AGYACNGTNYTNTCNTCNYTN---CCNCARCCN GGNTCNCARCCNTCNTCNATHCARCAYAGYATGGTNCARYTNGCNCAR------------ ------------------------------------------------------------ ------ATGCCNCCNCCNGCNGTNCCNGGNYTNGGNTCNCARCARCARGTNAAYTCNAAY CARGCN------TCNCARYTNMGNATHTCNTCNGTNYTNCARCARCARCARCARCARCCN AGYYTNTCN------GGNCARACNAGYATHAAYAAYAGYYTNCARCARMGNCCNAARCCN CARMGNTCNAARYTNCCNCCNCCNTCNAARATHCCNTCNTCNGCNGTNGARATGCCNGGN CAYATHCCNMGNAAYCCNCARYTNGAYYTNCARTTYGGNATHGAYTTYGGNACNGARCCN ACNTCN---TTYGGNTTYGGNGGNAGYGGNGAYGGNGCNGCNGTNACNACNACNTTYTCN ACNACNTCNAAYGGNACNTCNTCNGTNATHTCNAAYCAYYTNAAYCARAGYCAYGTNAGY CARCCNAGYGGNGAYGGNGGNTCNACNGAY------ATGTCNTCNACNACNTCNGGNTCN GCNAARGTNCCNACNGGNATGGARCCNCARACNACNGCNMGNCCNGGNGGNATHTTYCAY AAYTCNGTNTAYACNGCNTCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CCNACNGCNATH TCNTAYYTNCCNYTNCCNCARYTNTGGGGNATHYTNTTYTTYGTNATGYTNTTYACNYTN GGNYTNGAYACNCARTTYACNATGGTNGARACNYTNATGACNACNYTNTGYGAYYTNTAY CCNMGNTTYATGTCNAARTGGMGNAARTCNATHACNACNTCNTTYATGGTNATHYTNACN YTNYTNGGNATGGTNTTYGCNACNMGNGGNGGNATHTAYYTNTTYTCNYTNGTNGAYTGG TAYATHGCNGCNTTYTCNYTNYTNGCNCARTCNGCNYTNGARTGYTTYATHGTNTCNTAY ATHTAYGGNGTNGAYMGNTTYTCNMGNGAYATHGARYTNATGATHGGNMGNAARCCNTCN YTNATHTTYATHYTNTCNTGGAARTAYATHACNCCNACNATHYTNGTNATGGTNYTNYTN GTNACNYTNACNACNTTYCARCCNCCNCCNTAYGARAAYTAYACNTTYTCNTCNGCNGCN GARATHYTNGGNTGGGTNTAYGCNGTNATHCCNTTYATGTCNATHTTYGTNGTNGCNTTY TGGCARGTNYTNTCNMGNAARGGNTCNYTNAARCARMGNYTNCARAARAGYTGYGTNCCN GARCCNGARTGGGGNCCNTCNYTNCCNGARYTNMGNGARAARTAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TGYAGYGARAAYGCNGGNACNAAYGTNACNTGYGAYTAYTTYAARTGYGAYMGNGARGAY GCN---------TAYTCNGCNTCNAARGCNGCNCARGCNGGNGCNTGGATHAGYACNTTY YTNTGGYTNTTYGTNGGNYTNTGYGGNTTYYTNATHYTNYTNMGNGAYGGNAARATHCCN TTYYTNCARGGNGGNGCNGCNGCNAAYCARGGN---ACNGGNGCNGARGGNGARGCNAGY CCNCCNCCNATHGARACNCCNCCNAAYAAYCCNGAYGAYATGCCNMGNTAY--------- ------------------------------------------------------------ ------ACNTGYAARTGYGGNYTNGARTGYCCNGTNCARYTNGAYAARGCNTTYAGYTTY GAYCCNAARGTNGARGGNCARCARTGGGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------MGNMGNYTNTGYTAY--------------------------- AGYAAYGTNGAYGAYYTNGARAGYCCNTCNYTNCCNYTNACNGARACNGCNGTNGAYTAY TTYCAYGARAGYATGCCNTAYGCNGARGGNYTNGGNMGNYTNGAYYTNAGYACNGCNTCN MGNATHAGYAGYCARAAYAGYGTNTCNCCNTGYTCNATGGTNATGTCNATGYTNTAYGCN AARMGNYTNMGNCAYMGNAAYAARAARTAYYTNGARTCNATGTCNTCNTCNGAYATHTTY TTYATHTCNATGATGATGGCNAGYAARTAYYTNTAYGAYGARGGNGTNGARGARGARGTN YTNAAYGAYGARTGGGCNGARGGNAGYGGNCARGARGTNGARGARGTNAAYCARATGGAR ATGGARTTYYTNGARGCNATGAAYTGGGGNYTNTTYGTNMGNCCNGAYGARTTYGAYGAY GCNYTNACNGCNATHGARMGNMGNYTNGCNYTNCARGARGGNYTNAAYMGNGGNTGGTTY ACNTAYACNGARYTNACNGCNYTNYTNGAYTCNAAYYTNYTNCAYGCNYTNTGGAAYGAR GTNGCNYTNGAYTGYTCNATGYTNGCNACNGTNTTYTCNACNGCNTAYYTNGCNAGYYTN YTNAGYATGGTNGCNTCNGCNGCNYTNGCNGTNCARYTNTCNGGNCCNYTNACNTCNGCN ACNATGGCNGGNGTNTCNATHCAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGTNTGYGTN CCNTGYGTNATHATHCCNTTYGTNYTNTGGGTNTTYTAYAARTTYATHAAYCCNTGGYTN TCNAARTTYTGGTCNAARTCNGAR---TAYGTNYTNAGYAAYYTNACNTGYCCNATGCCN CARAARAARAAR------------------AARGAYGAYGGNACNACNCARAARACNGGN ACNGARACNGARGAR---TCNAAYGCNGGNTTYTTYMGNGGNACNACNGCNCARCARGAY ACNMGNTTYTCNGAYAARAARAARAARYTNATGAARACNATGAARTTYGGNGARGGNYTN GARMGNAARGTNGAYATGACNAARGTNAAYGTNGAYAGYYTNAARCCNTGGATHGCNCAR MGNATHACNGAYYTNYTNGGNATHGAYGAYGAYGTNATHGTNGARTTYGTNTAYAAYCAR YTNGARGARMGNCAYCCNGAYGCNAARGARATGCARATHAAYYTNACNGGNTTYYTNAAY GGNMGNAAYGCNMGNACNTTYYTNTCNGARYTNTGGGAYCAYYTNTGYAGYGCNCARGAR AAYATHACNGGNATHCCNAAYCARTTYYTNGARCARAARAARAAYGARATHAARCARMGN CARGARGARCARGARMGNATHCARGARGCNYTNAARAARAARGARGARCARATHAARGAR CARYTNTCNMGNGARMGNMGNGARYTNGARAARAAR------------------GARYTN AAYAAYYTNTCNCCNGGNMGNYTNCCNGAYAARGARGARACNAAR---GGNAAYYTNAAR ATGGAYGAYAAYTCNTCNAARYTNTCNCARGAYAARCARGCNGARGAYATGAARCARGTN CCNGTNATHTCNGCNGAYTCNAARGTNGCNACNGAYGTNGCNAARCARGARGTNTCNGAR AARAAY------------TCNAARGARAAYGARAARGAYMGNTCNCCNGARAARMGNCAY GAYGAYMGNGAYMGNGAYMGNMGNMGNCCNTCNMGNATHATHGARAARCAYMGN---GGN MGNTCNMGNACNCCNGAYMGNCAYMGNGAY---MGNGAYAARGAYMGNGCNCCNTAYGGN MGNAAYMGNTAYTCNCCNCCN------------MGNMGNMGNTCNCCNMGNMGNTCNMGN TCNCCNAARMGNMGNTCNYTNCCNCCNAARAARMGNTCNCCNCCNMGNMGN--------- ------------------TCNCCNTCNCCNAARMGNMGNCCNMGNTCNCCNMGNMGNGAY GCNATHAARAAR---------------MGNGAYCARTCNAGYAGYGGNAGYAGYTCNAGY GARTCNGAYGAYAAR---------TCNAAYGARGAYACNTCNCCNGAYAARGGNGGNATH CARCARMGNMGNAAYTAYMGNAARCAYGAYGARGAYAGYGGNAARGAYTCNTCNTCNGAR GAYTCNGCNGTNGAYGARMGNAGYMGNMGNCCNCCNCCNCCNCCNYTNAAYMGNMGNAAR ---------------------MGNMGNACNAGYCCNTCNCCNATGATGMGNMGN------ ---MGNMGNACNCCNGARCCNMGNMGNATGAGYCCNCCN--------------------- ------MGNMGNMGNTCNCCNGGNMGNMGNMGNCCNAGYYTNTCNCCNMGNMGNMGNTCN CCN------------TCNCCNMGNMGNMGN---TTYTCNCCNATGMGNMGNMGNAGY--- ------CCNCCNMGNMGNMGNATHTCNCCNTCNCCNMGNGGNCAYGCNTCNCCNATHCCN CCNMGNGGN---MGNMGNCARGTNTCN------CCNTCNCCNCCNAARMGNMGNCARMGN CCNTCNCCN---------TCNCCNCCNCCNGTNMGNCCNAARAARCARCCNCCNCCNCAR GARTCNGARTCNGARGARGARAGYTCNAGYTCNGAYGARGARGARTCNTCNCCNCCNCCN CARCCNAAR------ACNTCNAARGGNAARCARGTNGTNAARGAYAARAARCCNCCNCCN GCNGCNTCNAAR---------------------------------GAYGAYGARTCNTCN TCNTCNGARTCNGAYAGYGAYGARGAYTCNGARGARGAYTCNGARACNCCNTCNCCNGCN AARAARTCNAARGARGCNCCNCARTCNAARGCN---------------GCNCCNCAR--- ------------TCNAAR------GCNGARAAYATHAARGCNGTNTCNAARMGNCCNGGN ---------------------MGN---------------GAYATGTCNMGNTCNGTNTCN CCNAARCCN------------------AARCCNGAYGTNMGNMGNTCNTCNCCN------ ------------CCNCAYMGNAGYCCNGGNMGNAAYCARGCNMGNGAYGAYGGNTCNGTN YTNMGNCARCARMGNGAYTCNAGYTCNGTNGAYGAYCAYGGNGGNACNGGNMGNGAYMGN MGNTAYMGNAAYATHTCNCCNNNNNNNNNNNNNNNNNNNMGNTCNCCNTCNCCNMGNGCN AARGGNAARTCNNNNCCNNNNCCNMGNGCNAARGGNAARTCNAGYCCNCCNMGNCARTCN CCN---CCNCCNMGNAARCCNTCNCCNCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNTAYYTNGAYCCNAAYCAYTCNCAYTTYATHYTN--------------- ---------------------GGNYTNMGNTCNCARMGNYTNGAYYTNAGYGGNGCNTCN TAYCCNCARTTYGCNAGYAAYGAYGCNMGNACNGARACNTTYCARAAYTGGGAYCCNGAY CAYCARCAYAARGCNGARGAYYTNGTNGTNATGGGNTTYTTYTAYGCNGGNTAYTCNGAY TGYGTNMGNTGYTTYTAYTGYGGNYTNGGNYTNAARTAYTGGMGNCCNMGNGAYGAYCCN GCNTAYCARCAYGCNMGNTTYMGNCCNCAYTGYYTNTAYAAYMGNTAYGTNMGNGGNCAR GCNTTYGTNGAYMGNGTNCARCAYGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TGYTGGGAYYTNMGNYTNMGNCARYTNYTNGGNGTNMGNTAY GAYAGYMGNYTNAAYGCNTTYGAYTGGGAYTAYAAYATGGARYTNATHGARMGNGGNGGN TCNATHGTNCAYYTNAARCARTAYAARAGYTGGMGNGAYGAYGGNATHGCNTTYACNATH MGNGARGGNACNTAYGAYGTNCCNAAYMGNACNYTNTCNTCNGCNATGGTNTTYAARCAY GARGGNGARMGNTAYCCNMGNMGNGGNTTYTGGGGNGAYATGGTNGTNTCNCCNTAYATH GCNTTYGGNATHGARACNGARGARAARTCNYTNTAYAARAARCARAAYAAYCARCAYACN AARACNTCNGARGAYGTNGCNGARTTYAAYYTNACNTTYYTNTTYCAYGARYTNGCNAAY GAYACNAARTAYGARCCNCCNAARCCNGARTCNAARGAYACNATHAGYGARGARAARGAR GGNAARGARACNGCNACNYTNGARGARATHATHGARGGNGARGARGARGARAAYGAYGAY TCNAARGARAAYGARAAYGGNCARGARAAYAARCARGCNGARGARGGNAARGARTCNGCN GARCARACNGARAARGAYTAYGARTGGATGGCNATHGAYGAYGTNAARGTNATHTTYYTN CCNYTNGCNAGYATHACNGARYTNTCNMGNAARAGYMGNTAYGARAARTTYTTYGAYGTN GTNTTYTTYTCNAAYAGYATGGTNCAYAAYYTNAARCCNGARTTYTCNAGYGTNTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNYTNGGNGCNGTNACNGCNYTNAAY MGNCCNMGNGGNGTNTCNATHGARAARGCNTCNTTYTAYCARAAYCARGCNGGNTTYMGN TGYTTYTCNAAYGGNCARGTNATHCCNGGNGAYCAYGTNAAYGAYGAYTAYTGYGAYTGY GARGAYGGNTCNGAYGARCCNGGNACNTCNGCNTGYGCNAAYGGNYTNTTYTAYTGYGAR AAYAARTCNTTYAARGGNGTNNNNATHATHTCNTCNMGNGTNAAYGAYGGNATHTGYGAY TGYTGYGAYGGNTCNGAYGARTAYGAYAAYACNATHACNTGYGARAAYACNTGYGCNAAR YTNTAYGARGTNGARMGNGARCARCARGARGCNATHMGNCAYAARCARGARGARGGNTAY AARYTNAARCARGARTAYATHCARCARGGNAARMGNACNAARGAYGARAARYTNTCNAAR YTNAGYGARYTNGARAARGARAARGARACNYTNACNGARGARAARAAYAAYGCNGARTAY YTNAARATHGAYTAYGARGARCCNGARAARGCNGCNATHGAYGARCAYAARAARAARTGG GARGARGTNCARGCNGARAARCARAGYGCNAARGAYACNGARACNGCNTCNYTNGCNTTY GGNACNYTNGAYATHAAYCARGAYGGNGTNGTNGAYTAYCCNGARYTNATGAARCAYAAR GARTTYGAYATHGAYTCNGAYGGNACNGTNAGYGARGARGARGCNMGNGARTAYYTNGAR GARAAYGARCARGTNGAYGTNGCNGTNTTYACNGARAARATHTGGCCNAAYATHAARGAR ATHTAYAARYTNACNGGNGARCARAARGARGARGARGCNCCNAARGCNGARGARGCNGAR AARGAYCCNNNNCCNGARGTNGTN---------GARGGNGGNACNCCN---GAYGAYAAR NNNNNNNNNNNNGAN--------------------------------------------- ---------------GANGAYNNNNNNNNNGAYTAYNNNNNNGARACNAARMGNYTNATH GCNGCNGCNGAYGARNNNNNNNNNNNNNNNNNNGANNNNNNNNNNNNNNNNNNNGAYNNN GARAARGARATHAGYAAYATHMGNAGYTAYYTNGARYTNGAYYTNGGNCCNGARCARGAR TAYGCNTCNYTNAARGCNGCNTGYTTYGARTAYACNGAYMGNGARTAYACNTAYMGNYTN TGYCCNTTYGAYAARGCNACNCARAARTCNAARGCNGGNGGNATHGARACNTCNYTNGGN AAYTGGGGNCAYTGGCAYGGNCCNGARGGNGAYAARTAYGAYGCNATGAARTAYGARAAY GGNCARGGNTGYTGGAAYGGNCCNCCNMGNTCNACNCAYGTNAAYYTNCAYTGYGGNTCN GARAAYGCNYTNACNGGNGCNTCNGARCCNAAYMGNTGYGARTAYCARTTYGARTTYACN ACNCCNTCNMGNTGYTCNTCNCCNGTNCARGTNGARTCNCAYAGYGTNCAYGARGARYTN YTNGARATHAARGAYCAYCCNAAYTCNTAYACNGTNAGYATHGGNGGNAAYGCNYTNYTN ACNTGYGARGTNTGGGGNGAYGGNGAYATHCAYTAYCARTGGATGAARACNGARGARGAR YTNACNGAYGGNCCNCARGTNMGNGGNTCNCARACNAAYGARYTNAARYTNYTNAARATH CARGAYTGGGARTGGACNGGNTAYTAYMGNTGYAARATHTCNMGNMGNYTNGARGTNATH TAYACNAAYGARGCNGTNYTNCARYTN---TCNMGNGAYCARCARTTYMGNCCNATHCAR GTNTTYACNGCNACNGAYAARGTNGCNYTNYTNATGGGNGCNAGYGAYTAYMGNAGYGAY MGNCCNYTNACNGCNCCNGARAAYGAYGTNAARACNYTNGCNAAYATHTTYGTNTCNYTN AAYTTYAARGTNGTNTCNYTNYTNAAYYTNACNAARTCNGARATGATHGCNGCNATHGAY GARTTYAARTGYYTNGTNGGNGARGGNGTNTAYTGYGTNTTYTAYTTYTGYGGNCAYGGN TTYGARGCNAAY---CARTGYTTYYTNGTNCCNCCNGAYGCNMGNCARGGNTAYGAYCAY ACNGAYTGYATHTCNGCNGARAARATHTTYTTYAAYGTNYTNGTNAARCARMGNCCNGAR ATHTGYTGYATGATHYTNGAYATHTGYMGNAARAAYMGNGGNCCNACNAARCCNGAYATH YTNCARMGNGARGTNGARGARAARGARAAYTAYATHGTNTGYTAYGGNACNTCNTGYGGN YTNAAYGCNTAYGARTAYAARAARGAYGGNATHYTNGTNMGNCAYYTNAARAAYATHYTN YTNTGYGAYYTNGGNATHGARGAYGTNTTYTCNAARYTNMGNGCNGARATHAAYAARGAY CCNATHYTNAARYTNAARACNGAYGGNAARGTNGTNATHCARAARCCNGARGTNMGNACN ATHYTNTCNGARCCNCARMGNTCNTTYCAYGAYMGNATHGTNACNCARGGNTAYACNGTN GCNTGYGARCARMGNCARGAYGCNTGGGARMGNGCNCAYAARAARCCNAGYACNMGNAAY GTNCCNGTNTCNTTYCCNGGNTTYGARGTNGTNATHMGNYTNGAYTTYCARCARGTNTTY TCNAAYGTNYTNAARATHTAYACNTCNGTNATGGAYCCNGGNCARAGYAARACNTGYCAR GCNTAYATHAGYGCNGTNCCNGCNGAYGTNTCNTCNAARGCNMGNATHTGGACNATHCAR AGYGGNACNACNACNGAYYTNTGYAARAGYTAYGTNGTNYTNTAYGAYATHCARMGNYTN AARGTNGAYYTNCARYTNGARATHACNGTNGCNGTNYTNGARGAYGAYCAR--------- ------------------------------------------------------------ ---------------------------------------TGGAGYTTYGARTTYGCNGTN ACNYTNGCNACNATHYTNTCNATHAGYGCNTTYYTNACNATHGTNGGNAAYATHATGGTN YTNATGGTNATHATHMGNCAYMGNGGNATGMGNACNMGNACNAAYYTNTTYYTNGTNAAY YTNGCNATHGCNGAYYTNYTNGTNGGNYTNGTNGTNYTNCCNTTYCCNATHAARACNYTN ATHGARGGNGAYTGGGTNTTYGGNAARGCNATGTGYTCNYTNAAYGGNTGGATGAAYTGY TTYTGYYTNGTNACNTCNATHCAYACNYTNATGTAYATHGGNATHCAYAARTAYTTYTCN ATHGTNCAYCCNYTNAAYAAYCCNATHAARYTNAGYACNATHATHTAYATGATGGCNGCN GCNTGGATHTGGGGNGCNATHTGYGCNACNGTNACNGTNACNGGNYTNAAYACNGTNGAR TAYAARCCNGGNACNTCNCARTGYGGNCCNAARTAYCCNGTNAAYTCNAARGGNTAYGTN TTYCAYGGNYTNATHCARATHACNGTNATHATHGTNCCNTTYYTNATHYTNYTNTAYTGY TAYATHMGNATGTTYCAYGARATHAARYTNCAYTCNCARMGNYTNYTNACNAAYTCNACN GTNGARGARGAYTTYATHATHACNCARCARAARAARGTNATGGTNACNYTNTTYATHGTN YTNGCNACNTTYATHATGATGGCNYTNCCNTAYCAYGTNTAYGCNACNTAYACNACNATH GARAARGAYAARACNCAYTTYCCNAGYTAYATHAAYCCNYTNGCNTAYATGTTYYTNTAY YTNAAYTCNATGTGYAAYCCNATHATHTAYGCNTTYMGNTCNCCNGCNTTYMGNGARGGN TAYAARGARATHYTNTGYCARACNCCNAAYTAYGTNATHAGYGAY--------------- ---------------------------GAYATHGARTCNATHCCNGARTTYYTNATHYTN GAYTAYTGYAAYATHACNTCNACNYTNGAYYTNAGYTTYAAYMGNYTNCARTCNYTNAAR GGNYTNGARCAYTTYAARTAYGTNAARGARYTNATHYTNGAYAAYAAYGARYTNCAYGAY YTNGTNGTNTTYCCNYTNYTNMGNGARYTNCARACNTTYACNGTNAAYAARAAYAARTTY GARGAYYTNAAYCAYYTNGTNTCNCARYTNGARGCNAARTTY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYACNCAYGARAAYGAR GARTTYYTNAARATGTAYCARYTNMGNGAYATHATHTTYATHAGYACNGGNYTNTAYGAR CARACNYTNAAYATHGARAGYMGNGARMGNAARAARAARAARCARMGNYTNTGG------ ------------------------------------------------------------ ------------------YTNAARCCNGGNAARAARACNAARGGNMGNGTNAARATHAAR ATGGARTTYATHGARAAYAARYTNMGNMGNTAYACNACNTTYAGYAARMGNAARACNGGN ATHATGAARAARGCNTAYGARYTNTCNACNYTNACNGGNACNCARGTNATGYTNYTNGTN GCNAGYGARACNGGNCAYGTNTAYACNTTYGCNACNMGNAARYTNCAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARGARCAYATHTTYTGGGARTGGATGAAYAGYGTNYTNACNYTNTAYACNCARGAR--- ------AAYAARAAYTAYGGNGARTCNTCNGARACNGARTCNGTNTTYYTNTCNYTNCCN GTNTCNGTNGCNGARAAYATHYTNGTNGTNMGNACNCARYTNGTNGAYTTYATHYTNAAY CAYGARGCNGGNATHGARGAYYTNGARAARTTYATHTCNAARAARAARGTNTCNMGNCAR GARTTYGAYATH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATHGCNCCNAAYYTNGGNACNTAYMGNGGNGGNTCNYTNCCNAAY GTNAAYCARATGTCNAAYAAYCARAGYATHGAYYTNCARGCNACNYTNCARCAYYTNGAY GAYATGAARCARGGNMGNACNAGYGCNGAYMGNACNCAYGCNMGNCARGAYMGNCARMGN CARCARATHGGNGTNCAYMGNMGNAAYTTYCCNCCNGAYAARACNCCNCCNTCNCAYMGN MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNACNYTNGAYTGYYTNAGYTCNGARGGNMGN AGYGTNMGNTTYCCNMGNTTYAGYCCNGAYATGAGYMGNYTNATHTAYYTNGAYACNGTN CARGGNGGNGCNCAYAAYAAYTGYGCNCARYTNGTNATGATHGAYTGGCCNGARMGNGTN AGYAARGTNGTNGTNAARGARGTNGAYTTYGCNCCNATGCCNTCNTTYCCNGGNATHTAY ACNTTYTCNATGGCNMGNAAYGTNTGGTTYGAYGAYAAYGTNCAYYTNGCNYTNGARACN GCNTGGMGNAGYGAYYTNGCNGTNYTNATHATHAAYACNAAYACNGGNGAYGTNAARMGN ATHGTNAARGAYACNGARAARGGNTCNATGTCNYTNYTNTGYGTNGARAARAAYTAYGTN TTYYTNTCNGCNTCNTCNYTNGAYCARCCNCCNCAYYTNYTNGTNGCNAGYATGCARAAY CCNGCNGAYYTNGAYTCNGCNGTNTGGTAYTAYCCNGAYGGNGCNCCNCAYACNYTNGAY TGGYTN---ACNTGGAGYYTNYTNCARCAYCARCCNACNCARGARMGNAARAAYCCNCAR AAYGARTCNYTNGAYTAYGARAGYATHYTNTGYYTNCCNAARYTNCARGARGARGGNAAY YTNCCNCCNYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGGGNGARGGNMGNGARMGNGAYGARGCNTTYGTNACNYTNGCN ACNAAYGAYACNTAYTCNYTNGGNTGYYTNGTNYTNGGNAGYTCNYTNMGNMGNGTNTGY ACNTCNMGNCARYTNGTNGTNATGGTNACNTCNGGNGTNTCNTCNCCNATGMGNCARCAR YTNGGNGGNTAYTTYGAYCAYGTNATHGARGTNAAYGTNYTNGAYAGYAGYGAYACNTGY AAYYTNGARYTNYTNGGNMGNCCNGAYYTNAGY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TTYACNCCNATHTTYCCNYTN YTNGAYGCNGCNGCNTAYGAYTGYYTNGGNGAYGAYMGNCAYYTNTGGGGNAARCARMGN GTNTGGGGNACNTAYGGNTTYGCNYTNTTYATHACNTCNTCNTTYATHYTNMGNAARGGN AGYAAYTAYACNATHYTNTTYTAYATHTTYGCNGCNYTNAGYYTNATGGCNGCNTTYGTN GCNAARTTYATHMGNTTYTCNTCNAAYACNMGNTGYGARGARTTYGTNAARAAYGTNTGG GCNYTNYTNTCNTAYAARGARGTNTCNGTNTTYYTNTTYATHGTNATGTAYTTYGGNATH GCNYTNGGNGCNYTNGARGCNTTYYTNTTYTGGTAYYTNATHGAYYTNGGNAGYTCNCCN YTNGTNTTYGGNTTYATGYTNGTNGTNGAYTGYATHGTNGARATGCCNATGYTNTGGGCN GCNGGNACNATHATHAARCAYATHGGNYTNGTNTCNTGYYTNTAYTTYGCNYTNYTNTGY TGYGGNYTNMGNATGYTNGCNTAYTCNYTNYTNCARAAYCCNTGGTTYGTNYTNYTNGTN GARCCNGTNCAYGCNGTNACNTTYGCNYTNATGTAYGCNGCNGCNTCNTCNTAYGCNAGY ATHATHTCNCCNCCNGGNATGTCNGCNACNGTNCARGGNYTNYTNAGYGGNGTNCAYTTY GGNTTYGGNAARGGNATHGGNAGYTTYGTNACNGGNTTYATGTGYGARAGYATHGGNTAY MGNTGGACNTGGMGNGTNTTYGCNATHATHTCNATHYTNYTNYTNGTNATHTAYTTYYTN YTNAAYGTNTTY---TCNGCNACNGAYAGYATGAARYTNYTNTCNAARAAYAARACNGAY GAYCARAARACNATHGTNCCNCARACNGARGTNGTNTCN---------------CCNGAR ACNGARTCNGARAAYGARCCNYTNGAYACNAAYCAYAAYMGNTAYGTNTAYMGNGGNGAY ATHTAYGCNATGCCNATHAARGAYAARAAYATHMGNYTNGTNGARGARGAYGARAAYCCN ATHATHTCNMGNATGAARGARATGYTNATHGARAARTCNMGN---AGYAGYAAYCCNTCN TCNCCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNACNCCNACNTTYTCNGGNGGNAGYACNCCNAAYMGNCARTCNMGNCCNTCNTCNCCN GCNTGGAGYGARAGYAGYGGNAGYATGAGYACNTGYAGY------GTNAGYAGYTCNACN GGNACNAARAAYGGNAAYYTNAAYAAYCCNGTNCCNMGNCAYAARMGNCCNTCNCAYAAR MGNGCNGARGTNAARMGNMGNGAYAARATHAARACNTAYYTNGAYGAYYTNAARGAYCAR GTNCCNTCNYTNCARGGNAARGGNAARYTNAGYGARTCNGCNATHYTNTCNAARGCNGCN GARTAYATHCAYCARYTNAARGAYGGNTGYTCNAARMGNGGNTGYAARAARGCNGARYTN MGNCARGARATHCARTGYYTNACNGARGARATHCARAAYTTYCARGARAGYYTNCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGCNTCNGAR AGYMGNCCNMGNAGYYTNTAYCARYTNGCNTTYAGYTGGTTYGCNGTNATHATHTGYGGN YTNCCNYTNTTYGCNTTYATHTTYTGYGTNYTNTGGTCNYTNATHTTYCAYTTYGARCAR ACNACNMGNACNCAYTGYMGNGTNCARAAYTTYYTNCCNTCNGTNAGYGCNGGNGTNCAY TCNCCNCARAARTAYGTNTGGMGNATHTGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ACN TCNGAYATHCARTTYAARACNCAYYTNCAYAARAARATHAAYAAYTAYCARCARTCNTGG CCNGTNTAYGAYATHATHCCNATG------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GAYGAYAAYCCN TCNTTYGARGCNTCNGARTCNATHMGNAGYTTYAAYTCNAGYGCNGAYGARTTYAAYTGG GARGGNGGNGARGARATGGARGARGARMGNACNTCNYTNCCNCCNCAYYTNAAYCARTCN YTNTCNGAYYTNCARTTYAARCARTCNYTNATGCARMGNATHCARGARTGGTCNAAYTTY GCNGARGARTAYAAYGARTCNMGNTCNCCNACNCCNGAYTGYTCNCCNATHMGNTTYGTN MGNMGNAGYMGNTCNYTNGAYMGNCAYATHGGNGAYCCNACNYTNGCNGCNGARACNGAR GARATHGCNGGNTCNAARCCNATHGARATHGAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN TCNGARAGYTCNGAYGGNAARTTYATHTTYGTNGGNYTNCCNAAYGGNYTNGTNGTNATG GAYGCNYTNTCNCARTCNYTNYTNTCNAARTGGGARGAYGARCAYGCNGARATHTCNAGY ATHAARAAYTAYACNTTYTCNACNCARTGYGCNYTNGTNACNACNYTNGAYGAYATGGCN GTNTGYMGNYTNTTYYTNTTYGCNTGYGAYCAYYTNTTYTTYATHAARACNATHAAYGAR AAYGCNCCNAAYGCNGCNTCNAARATHYTNTGYCAYAARTGYGARGCNTCNAAYGAYGGN GAYTTYGTNGGNATHATHYTNGARAAYACNGGNAGYAARGARATHTGGTTYGARGCNCAY AARYTNCCNACNGAYAAYTGGGTNAARGARYTNGARGGNATHAARGCNGCNGTNATGAAR CARAARGAYGARAGYGARAARTCNCAYACNGARATGACNGARGGNCAYCCNGAYCCNGTN GARACNACNGCNCCNGCNGCNGARCAYCARAARGGNGARGCNTCNTCNGCN--------- ATHGAYGCNGTNATHGARAARYTNGGNACNAARTTYTCNYTNCCNCAYGTNGTNTTYAAR GTNAARAGYCCNTCNCCNYTNCCNYTNGCNGCNAAYCCNTCNTCNAGYTTYGCNAGYACN GTNTCNAARGTNGAYCARGGNGAYATHYTNGGNGTNGGNCARTCNCAYGTNTTYAGYACN GCNCAYATHGARGCNMGNGAYTCNATGTTYAAYCAYMGNCAYGARAAYATGYTNGARTTY YTNAGYYTNGARGARGARGAYTCNACNYTNTCNGCNTCNTTYCAYTTYYTNAAYGCNAGY MGNATGATHACNTTYGGNYTNGARCARTCNYTNCCNGCNAGYAARTCNGTNGCNGTNGCN ATHTGGTGGATHGGNACNCCNCAYYTNTGYCAYTAYTCNYTNYTNAAR---ATHGGNAAR GAYYTNGARTTYAARCCNGAYATHGTNTGGCCNTTYACNAGYTAYATHACNTGYTCNGCN ATHAGYCCNTGYACNTCNTAYATHGCNGTNGGNYTNGARAAYGGNAAYYTNGTNYTNTGG GAYTAYCARATGGGNYTNTCNAARGCNGCNYTNAGYGTNTCNAGYATGTGYGGNGTNAAR ACNGTNMGNTTYYTNGAYCCNTGYYTNTTYCCNTCNGARYTNCCNCAYTAYCCNCCNTAY CCNGTNTCNGCNGCNACNTTYATHYTNGCNGARTGYGTNGAYGGNACNCARTCNYTNTAY GAYACNTGYGAYGGNAGYYTNCARGTNCCNMGNTGYATHGCNTCNAARCCNGARAARGAY GAYGARATHCARACNYTNYTNAARACNGTNCCNGARYTNCCNGARYTNATGATHTAYGTN CARAARAAYGGNTCNATGTTYATHAARGAYATHGGNACNGGNGCNACNYTNTGYCARATH GCNGTNCCNTCNACNCAYAGYATHCARAAYGCNTGGGAYCCNATHTTYGCNYTNGGNGGN GGNGGNCARATHYTNTAYYTNAARGGNGARGGNATHGAYGTNAAYGARGARGGNGARACN AGYGAYATHTCNTGYYTNTTYAARTAYCAYYTNMGNTCNTAYCCNGTNYTNGAYAARTAY TGGGCNMGNAGYCAYACNAARTCNGAYYTNATGGTNTAYACNACNCARGARAARMGNYTN GAYGCNYTNATGAARGARMGNYTNCARCARCARGCNGTNMGNAARCCNMGNATGCARAAR MGNTGGGGNCARYTNMGNTCNGARYTNGAYACNATHCARCAYGCNMGNCARATHCCNGTN GAYACNYTNCARYTNTGYMGNYTNGGNCAYTTYATGCARYTNTAYGARGAYTTYGTNGGN YTNTCNGARGTNAARGTNGCNCARGGNAAYGTNGTNGAYGCNGARAARCARTTYYTNCAR GTNCARGARTTYMGNMGNGAYGTNCARCARGAYYTNYTNACNATHCARGCNGAYYTNMGN TCNATHACNACNGARYTNGARAARACNAGYMGNACNGAYTCNMGNTAYATHGAYYTNGTN AARAARGARCAYGARATHYTNYTNGTNGARMGNGARATGGCNAARAARATHAARTCNYTN GARAARTCNGARMGNGAYTTYTTYTCNTGGYTNTCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNCCNACNTAYGCNACNCCNATHATGYTNYTN CAYAARGTNGGNYTNGARTCNAGYTCNACNGGNTCNTCNTTYCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYGAYGAYGAYGARTTY TAYGARGAYGARGTNCCNGARGTNACNTCNCCNACNGGN------AGYCCNMGNCCNACN ATHGGNAGYMGNGGNTAYAGYGGNCARGGNAARAARATHACNACNAARCAYGAYACNGTN GTNTGYGGNMGNMGNAAYGCNGARMGNYTNATGGARTTYCCNCCNGARTTYGARAGYGGN GAYGGNGARGGNATGAAYATGCARYTNCCNAAYAARGTNTAYAAYAARYTNAARGCNCAY TCNATHTCNGARAAYMGNAARACNCAYAARGTNCAYGARAARAARGAYCAYTCNACNGCN ATHAARGCNGTNGAYGARMGNACNMGNATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CARAARCAYMGNGAYCARCAYAARAARGGNGTNTGGGCNCAYTCNCARGTNATGAGY CAYCCNGTNATHCCNTCNGCNCARCCNYTNATGMGNGAYCCNGTNCARACNCCNCCNACN AGYAAR------AARAARGGNCCNCARCCNAARCCNGTNAARCCNGCNYTNAARCARGTN CARGARGARCCNYTNGAYGCNGAYGTNATHYTNATHMGNCAYGGNCAYYTNCARCCNCAR GARYTNAARGAYATGATHTTYMGNAARTCNGAYGAYMGNGCNGARAARAAYMGNAARTTY TGGATGGARGTNTAYACNAARMGNGARGTNMGNTAYTGGGCNAAYYTNMGNCCNTTYATG TTYAAYGTNGCNATGTCNAARMGNGCNTCNGGNGTNAGYGTNACNAARTCNTCNYTNACN TAYYTNATHAAYCARCCNATHGTNTGYGCNGGNYTNMGNAGYGGNGARATHYTNAARTTY GAYYTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYAAYGCNYTNGARAARYTNTCNMGNAAYGCN MGNYTNYTNTAYATHCAYAGYTAYCARTCNTAYGTNTGGAAYAAYATGGTNTCNMGNMGN YTNAARGAYYTNGGNCARCARATHATHGTNGGNGAYYTNGTNATG---AAYAARTCNGCN GAY------------------AARAARGTNTCNACNGTN------ACNGARAGYAAYYTN AARGARTTYAGYYTNTGYGAYGTNGTNYTNCCNYTNCCNGGNCAYGAYATHATHTAYCCN AGYAAYGARGTNCARGAYTGGTAYMGNGARYTNATGAARGCNGAYGGNYTNGAYATHGAY AAYATGAARMGNCCNCARAARGAYTAYTCNYTNCCNGGNGCNTAYMGNCAYYTNATGGTN GTNCCNTCNGAYATHTCNTGGACNCAYCARAARTAYGAYGAYTAYACNYTNCCNYTNACN YTNAGYGAYTTYGAYYTNYTNAARAAYCARGARCAR---CCNYTNATHYTNGAYTCNGGN AARTTYGAYGCNYTNACNYTNCAYATGTCNYTNCCNTCNTCNTGYTAYGCNACNATGGCN YTNMGNGARGTNATGMGNTGYGAYACNTCN------------------------ATGAAY CCNTCNMGNTCNYTNGGNTCNGCNGTNGCNTCNAAYAGYTGGGARGAYCAYTGGATHTAY TGGGTNGGNCCNATHTCNGGNGGNGTNYTNGCNGCNGTNGTNTAYAARTTYATHATHAAY CCNTAYCAYGGNGTNATHAAYATGGARGARGCNATHAAYAARYTNAAYGGNGAYGARAAY TTYGTNGTNGTNCCNAARGAYTAYTTYAARGAYGARGTNAARTCNGARGCNACNGCNATG ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TGYGARGTNATHTCNAAYACNYTNGGNTCNTAY YTNCARTCNGTNGAYAARACNCARYTNCARTAYGTNTCNGARYTNTAYAARGTNAAYACN GARAAYGTNCARAARATHGAYGARAAYGARMGNGGNGAYGTNAARATHACNGTNAARATH ATHATHAGYACNTCNCARCCNCCNAGYGTNATHGGNGAYGCNGTNGARAARGTNYTNCAR GARYTNGAYACNAGYTTYGTNGARACNYTNYTNYTNGCNGTNTCNMGNAAYACNGGNGAR GARGARGARTCNGAYGAYGCN---AAYYTNACNGCNATHAARAARTAYTGGCARGCNATG GARGAYYTNGTNTCNACNGAYAARGTNYTNTCNYTNGGNGTNTGYGAYYTNAGYAARAAY GCNYTNGARGCNYTNTAYGCNTGGTCNAARGTNAARCCNTGYGTNAAYCARGTNAAYYTN GARTCNTGYTGYGTNATGCCNAARGARYTNACNGARTAYGCNAARGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GTNAAYATHCARATHAAYGAYCAYYTNMGNYTNCAR CARYTNMGNYTNTTYGARYTNYTNATHAGYCARTCNCAYCARATGYTNYTNATHCAYAAR CCNGTNATHAARCCNYTNYTNAARYTNYTNATHGAYGTNACNGARTCNCARGARGTNYTN AAYGGNGARYTNGARTTYAARYTNGTNYTNGTNYTNCAYCARATHTGYATHTGYATHTCN CARCARGGNYTNATHYTNGARAGYTTYTTYAGYACNGAYACNGAYCAYGGNCCNGCNAAR TTYYTNATHTTYTCNYTNYTNATHCCNTTYACNTAYYTNGARGGNCCNGTNGGNCARAAR GCNMGNGAYGCNYTNYTNYTNATHATGACNYTNTCNTCNMGNCAYCCNCAYATHGGNMGN TAYATHGCNAAYCAYTCNCAYTTYTGYCCNGTNYTNGCNACNGGNYTNAGYGGNYTNTAY TCNTCNYTNCCNMGNMGNATHACNCCNCCNTCNGAYGAYTGGTAYGCNATHACNAARGAR GAYTGYGTNMGNATHCCNGAYYTNCARATGTTYATHAAYTCNYTNCARTTY--------- ------------------------------------------------------AAYGGN AAYACNATGATGAGYAAYYTNGARGGNGTNGCNGARMGNAARMGNMGNMGNAARAGYMGN TGGAAYACNGAYAAYGAYGARAARACNGTNATHCCNGGNATGCCNACNGTNATHCCNTCN AAYYTNTCNGARTCNCARCARMGNCARTAYGTNGTNCAYYTNCARATHGARGARATHAGY MGNAARYTNMGNACNGGNGARYTNGGNATHCCNTCNAAYCCNGARCARMGNTCNCCNTCN CCNGARCCNATHTAYAAYAAYGARGGNAARMGNYTNAAYACNMGNGARTAYMGNACNMGN AARAARYTNGARGARGARMGNCAYAARYTNATHCARGARGCNYTNAARYTNAAYCCNGAR TTYAARCCNCCNAGYGAYTAYAARCCNCCNGTNGTNMGNGTNAAYGAYAARGTNATGATH CCNCARGARGARCAYCCNGAYATHAAYTTYGTNGGNYTNYTNATHGGNCCNMGNGGNAAY ACNYTNAARACNATGGARAARGAYACNGGNGCNAARATHATHATHMGNGGNAARGGNTCN GTNAARGAYGGNAARATHGGNMGNAARGAYGGNCARCCNYTNCCNGGNGARGAYGARCCN YTNCAYGCNTAYGTNACNGCNAAYAAYCCNGARAAYGTNAARAARGCNGTNGAYAARATH AARGARATHATHAARCARGGNATHGARGTNCCNGARGCNCARAAYGAYYTNMGNMGNCAR CARYTNMGNGARYTNGCNYTNYTNAAYGGNACNYTNMGNGARAAYGAYGGNYTNCARAAR YTNMGNCARATHGCNGARAGY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYYTNGGNCAYYTNGARATGGTNCARGGN---GAYGCNTCN GARYTNCAY---------CCNGAYAAYATGACNGCNATHYTNATGCCNCARCARCCNGCN TCNCCNGARYTNCCNCCNGGNTGYCCNCCNTGGGCNTCNYTNYTNAARAARTGYGARAAR ATHGGNGAYTTYTAYMGNGGNTAYGTNGARAAYGARATHAAYYTNGAYYTNGTNYTNACN YTNCAYAARCARCARACNAAYAGYTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNGARATGGAYGARAAYGAYAAYAGYTTYCCNTGGGGNYTNYTNCAY CAYAGYGARYTNGCNYTNATGYTNAAYAGYGGNYTNGGNAARACNATGATHATHGAYAGY MGNTCNTTYYTNGARCAYAAYACNAGYAAYATHCARCARTCNGTNAAYGTNTGYTGYTCN AARYTNGTNAARMGNMGNYTNCARCARGAYAARGTNCAYGTNYTNGAYYTNYTNAAYCAR ACNTGYAAYATGGGNGCNGAYGCNAGYTGGGAYGTNATHGTNTAYGAYCARTGYACNGAR GAYCCNTCNYTNYTNGGNAARYTNAGYACNGCNTTYACNAGYGTNGCNTTYYTNAARGGN GGNTTYYTNGCNTTYCARGCNTCNCAYTCNAAYYTNGTNGARAAYAARTCNAGYAGYTGY TCNACNYTNACNTCNYTNTCNCARCCNTGYATGCCNGTNAGYAAYGTNGGNCCNACNMGN ATHYTNTCNTTYYTNTAYYTNGGNAGYCARCARGAYTCNYTNGCNCARGARYTNGCNCAR GTNAAYGGNATHACNTAYATHYTNAAYGTNAGYAARACNTGYCCNMGNCCNCCNCAYATH CCNGARAGYCAYTTYCAYMGNATHCCNGTNAAYGAYGAYTAYTGYGARAARYTNYTNCAR TTYTTYCARGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MGN AAYGTNAARGARATGATHGGNGGNTGYTGYGTNTGYTCNGAYGARMGNGGNTGGAGYGAR AAYCCNYTNGTNTAYTGYGAYGGNATGGGNTGYAAYGTNGCNGTNCAYCARGCNTGYTAY GGNATHGTNCARGTNCCNACNGGNCCNTGGTTYTGYAARAARTGYGARTCNCARGARMGN GTNGTNMGNGTNAARTGYGARYTNTGYCCNCARMGNGAYGGNGCNYTNAARMGNACNAAY TCNGGNGGNTGGTGYCAYGTNGTNTGYGCNYTNTAYATHCCNGARGCNTGGTTYGCNAAY GTNCARACNATGGARCCNATHGTNYTNACNTCNGTNCCNCAYGARMGNTTYAAYAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAY ACNYTNTAYTAYGAYTCNTGGTGGATGTGGCARCAYGTNTGYYTNACNTGGYTNAGYGCN YTNYTNATGYTNACNTCNCAYTTYYTNCCNCCNCAYTAYYTNCAYYTNYTNCAYAARAGY GCNMGNCAYYTNGGNMGNTGGCARMGNATGGARGCNMGNCAYGCNCAYATHCCNTAYAAY GCNTGGTCNGARYTNCARGTNTGGCCNCARGGNGCNYTNGTNAARCAYGTNMGNGGNYTN TTYAARGCNGARGGNATHAAYGTNACNGCNGARCCNGGNAAYAGYYTNCAYAGYMGNTTY TAYATGGTNTTYCAYCARCCNATGMGNGTNATGAAYTGGYTNGTNTTYYTNAAYTGYYTN GTNGTNGGNTAYCARTTYTTYMGNYTNGTNCARAGYTCNGARTGGAGYCAYATGATHTCN YTNGCNYTNYTNATGTTYTGYAAYTTYTAYACNYTNTTYAARYTNATGMGNGAYTGG--- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARATGGARGGNGGNGGNYTNACNYTN YTNACNGAYTCNCAYGAYTGYYTNTCNCARYTNTCNMGNACNAAYCCNAARAAYTGYGGN GTNTTYTGGMGNYTNTCNAARTCNTGYTTYYTNYTNGCNTCNGARGARCARATGCARAAY GCNGAYATHGCNCCNGAYMGNTCNAARCARYTNATGACNAARGCNAARGAYGCNGCNCAR CARGCNGTNGTNYTNGAYAAYGARTCNGTNGAYGCNCAYAARTGGATGGCNATHATHYTN GGNAGYATHACNCARTAYYTNCCNGTNAARACNCARATHGARAAYGCNTTYGTNATHAAR AARCAYATHGAYACNGCNATHTCNTAYGAYCCNGAYGAYTCNGTNATGCAYCAYATGYTN GGNMGNTGGTGYTAYTCNGTNTAYATGYTNTCNTGGGTNGARMGNAARYTNGCNTCNGCN YTNTAYGCNAGYCCNCCNACNGCNACNYTNGARGARGCNYTNGARTGYTTYGARCARGCN GARAGYYTNAARCCNYTNTCNTCNATHGAYAAYYTNYTNTAYYTNGGNAARGCNTAYATH ACNYTNAARGARCAYGCNAARGCNGTNCARTAYYTNGARTCNGGNYTNAARYTNACNTGY TCNATHCCNGAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ACNCCNGTNYTN CCNYTNAARCCNCAYCAYGCNGARTCNAGYGAYGARATHTAYGARGARGCNGTNTCN--- GAR---ACNYTNGAYTCNTAYGAYTGGTTYCAYGGNAARGTNGAYMGNTCNGAYGCNGTN TCNMGNGTNAARGARYTNGGNAARATHGGNGGNTTYYTNATHMGNACNAGYCARAGYACN CCN---------ACNCCNTAYACNYTNGTNGTNATGAAYAARTCNAAYGTNCARAAYYTN AARATHMGNCARMGN---GGNGAYGGNAARTTYGCNATHGGNAARMGNACNAGYGAYGAR YTNTGYTTYACNAGYYTNCCNGAYYTNGTNGCNCAYCAYMGNGAYAAYAAYGTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYCARGAYYTNYTNAGYCARATHMGNATHYTNCARGAR GARAAYGGNAARYTNCAYAGYGARGTNTCNMGNYTNAARCARAARTGYAGYGAYAARAAY CARMGNYTNATHCAYYTNAARAAYGAYYTNGAYMGNCARAARAARAARGARGCNGARGAR ACNTCNGTNATGGARAARGCNGTNCARCARGTNGARGARAAYYTNGTNACNAAYACNCAR MGNGCNGTNCARGCNGARTCNACNGTNYTNAARYTNAARCARGARGTNACNTCNYTNCAR AAYCARGTNCARACNYTNACNGCNGARAAYGARAGYTAYMGNAGYGGNGAYGGNGGNYTN TCNGAYATHMGNGARMGNACNAARTAYTCNTCNGARCARYTNGGNGTNGCNGCNGTNAAY GCNGARAARAAYYTNAARGARYTNYTNYTNGGNGTNGAYCARYTNAARYTNYTNTCNCAR GTNYTNTCNTCNYTNGARAARGTNACNGARGTNACNCCNGAYATHTTYCARAAYTGGAAR GTNCCNAAYMGNYTNGTNCCNGARGTNTCNCCNGAYGGNGGNTAYAARGARGCNTTYGAY GCNGTNYTNGCNGGNAARMGNGGNAARGGNCARACNMGNCCNGARYTNYTNMGN------ ------------------------------------------------------------ ------------------------GARATGCARGCNYTNCARGAYYTNGAYAAYGGNYTN AARYTNGAYCCNGAYCAYGTNGGNTGYYTNGTNGTNMGNGGNGCNATHACNMGNCCNYTN TCNCCNMGNTAYCCNGGNGGNCARCCNMGNCARAAYAARTAYYTNMGNAARGCNGARAAR GTNAAYCCNGAYTCNCARTCNTAYTTYGAYGTNGTNAAYTTYCARCAYCCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNGTNYTNACNGGNCARACNAGYGAYAAY ATHTCNAAYYTNGTNATGCAYGARGTNMGNGARATHGARACNTGGATHYTNMGNYTNYTN AGYGCNCCNGTNCCNGTNCCNGGNAARACNMGNATHGARGTNCARGTNYTNCCNMGNAGY YTNCARCCNCCNYTNYTNTTYGCNYTNCCNGAYAAYACNMGNTTYTCNYTNGTNGAYTTY CCNYTNCAYYTNCCNYTNGARYTNYTNGGNGTNGAYGTNTGYYTNAARGCNYTNACNGCN ATHATGYTNGARCAYAARGTNATHYTNCARTCNMGNGAYTAYAAYGCNYTNTCNATGTCN GTNATGGCNTTYGTNTCNATGYTNTAYCCNYTNGARTAYATGTTYCCNGTNATHCCNYTN YTNCCNACNTGYATGGCNTCNGCNGARCARYTNYTNATGGCNCCNACNCCNTAYYTNATH GGNGTNCCNGCNAGYTTYTTYGGNTAYAARAARGAYTTYCCNYTNCCNGAYGAYATHAAR ACNCAYYTNAARCARGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GARATHATGGGNCARYTNACNTCNMGN CARGARGTNATHAAYACNGARGTNAGYGAYTCNAARATGMGNAAYTGGYTNTGYGCNAAY ATHGCNATGMGNGAYACNTCNAARGCNYTNGCNGTNTGYGTNCAYAARAARATHGCNGAR ATHCAYAARCARATGYTNMGNACNGTNGGNAGYGGNCCNGTNTGYCAYMGNAAYTGYAGY MGNYTNGARGTNCCNTGGTGYACNGTNTGYGAYMGNTGGTAYAARGARATHGTNGCNGTN TGYGARCCNGAYTTYMGNTCNMGNATHAAYTGGAARMGNYTNAAYTCNGCNCARTGGCCN AARAAYCCNTAYGARGTNGCNMGNACNTTYATHCCNMGNGCNCAYMGNYTNTAYTAYAAR TCNGCNGARTTYCAYGARGAYTTYMGNTTYAGYYTNAGYTTYATHGARAAYTGYTAYGAR ATHCCNGTNTCNMGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATHGAYTCNCARACNGGNGAR TGGATHYTNTCNGARTGGGAYATHGARTGYATHGCNGTNGGNGCNGGNATHTAYGGNTGY GGNGGNGGNGCNAGYCCNCAYATGGGNMGNYTNMGNGCNYTNAARGCNGTNMGNGAYGGN AARMGNATGMGNGTNGTNCAYCCNGARMGNYTNYTNAARGCNTCNAGYGARNNNMGNCAR GTNGTNATHGCNTCNGCNTTYATHGGNGCNCCNYTNATHATGTAYGARCARGCNGTNTCN TCNCAYGARACNGCNACNTCNYTNGARTGYYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG GARGCNCARYTNGCNAGYYTNMGNMGNGAYCAYTCN------MGNAGYYTNGGNAGYACN GCNTCNGAYAGYTCNGAYACNTTYCCNGCNTCNTCNGCNAGYAARTCNGAYATHCCNAAY AGYCAYCAYGTNGGNGGNMGNTGGTCNGGNGARTCNTCNCCNGTNCCNGGNGARATHAGY CAYAARYTNAGYAARYTNAARTCNGARYTNCAYATGYTNMGNMGNCARCARCARYTNAAY ATGGARATHATGMGNGARGARTTYCAYTCNGCNTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GCNGGNYTNTTYYTNACN ACNGTNACNAGYATGTCNGTNYTNGCNGGNTTYGGNYTNACNYTNGGNATGGCNAARAAR GGNGAYCCNAAYATGTTYGARAARGGNYTNATGGGNTCNAARGARATHCCNGARAGYGGN GTNMGNYTNGCNACNMGNGCNYTNGCNMGNGGNACNYTNTAYTCNGTNACNGGNTTYGGN YTNGTNTGYTTYGCNATHTGGAARYTNATGGGNGTNCAYAGYATGGCNGARTTYMGNGAR AARGCNGGNACNGTNATGCCNAARYTNCCNAARAARGAYAAYCCNGGNMGNGGNGARTTY MGNACNYTNMGNGAYYTNYTNGARTAYATHATHGCNGARGAYGARAARGARAARAARMGN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYAARGARATGTTYGTNCCNGGNGCNTCNAARCARACN YTNGAYAAYYTNGCNAARGARAAYGCNMGNYTNMGNAGYYTNYTNAARAAYGGNAAYATH CAYYTNGARAARGAYACNTCNGAYAARGTNGARGARYTNAARGCNTGYGTNGARTCNCAR AARTAYGARATHTCNCARYTNCARACNGAYYTN---------GARGAYACNAARAARTGY YTNAARGARCARTAYGAYYTNAARATHYTNACNAARAARYTNAGYGCNGGNMGNGAYMGN ACNGAYGGNAAYCARMGNGAYAARGARAARGARAGYTTYTCNGARCCNGAYTCNGGNATH GARGAYYTNMGNGARYTNYTNAARAARACNGTNGAYCAYTGYTCNCARYTNGGNGARCAR YTNCARYTNTCNTCN------AARAAYGARCARCCNAAYYTNGARCAYACNAAYGCNAAR TCNCCNGTNATHACNGARGAR---GTNYTNAARATGAARAARGARCAYGARGARGAYATH ATHATGAAYCARMGNTGGCARATGTAYAGYCARAGYCARGCNCARMGNATHAAYGARYTN AAYAGYMGNYTNATHGARTTYGAR------------------YTNYTNATHAARTCNAGY ACNAARCCNTAYGARCARGARATHGARAAYYTNAARAAYATHGTNATGTCNAARGARGAR GAYATHAAYMGNYTNAAYGCNCARYTNCAR---------AGYYTNGCNAARGARGTNTCN TCNTAYMGN---------AARATHGAYTGGAGYACNGTNGARATHYTNAARCARCARATH CARGTNTGYACNGARGAYTTYAAYACNGARMGNAARGAYMGNGARYTNGCNGTNACNAAR GCNAARGCNYTNCARGARGARGTNACNAARYTNAARGTNGARAAYGARAAYATHAARGCN AARTTYCAYATHCCNGGNAARGAYCARYTNTTYCARTTYGTNGTNTGYTTYATHTCNTTY CARGARAAYTCNYTNGARYTNTTY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AGYGGNATHTTYTGYCAY TCNTGYCARACNYTNGCNTAYAARAARTGYAAYGAYCCNTAY------------CARGTN GAY------AAYYTNGGNGARTGYGAYGAYGAYCARTAYTGYGTNAARTAYAARACNATH GTNTGGYTNAARGAYTCNGGNTAYATHAAYGGNMGNGARMGNAARTCNGCNGTNGTNACN MGNGCNTGYGARCCNAARTCNAARAAYAARGARGGNTGYGTNGGNMGNAARAAYAAYGGN GGNGTNACNATHAARTGYTCNTGYGGNACNGAYGGNTGYAAYAGYGCNCAYTCNATHGTN CCNACNTCNAGYTCNATH------------------------------------------ ------------------------------------------------------------ ------------------------------TGYMGNMGNGAYGCNGAYGARMGNGTNACN GARYTNCARGARYTNATGAARTCNAARGAYGARYTNCARGARMGNGGNGARAAYGARAAR TAYGARYTNAAYACNMGNATHAARTCNATHAAYCARCAYTAYAGYATGYTNCARAGYCAR TAYAARGARACNGARGCNGAYTTYYTNAARYTNAARGCNGAYATGGARAAYATGMGNYTN GARCARCARCARGTNGARGGNCARCAYGCNCARGARTAYCARGARYTNAARGCNAAYMGN AAYAARGARATHGCNGAYYTNACNGARCARGTNAAYACNYTNAARTCNCARAAYGARGAR YTNCARATHGGNATHAAYTCNYTNMGNAGYCARGTNCAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNGTNGCNAGYCCNGCNACNTCNTCNACNAGY--------------- ------------------CARGAYGTNAARCCNAAYYTNAARYTNYTNAAYCARYTNGCN AAYAARTCNGGNGTNTCNCCNCCNTCN------------------TCNTCNYTNGCNAAY AARTTYAARTCNACNYTNTCNTCNCARCARGAYGGNTAYGCNMGNAARYTNGGNAARATG AARMGNGCNACNAARGAYACNATHTTYATHAAYGGNGCNGTNTGYGAYGARGTNYTNMGN ACNGARGARAARYTNGCNAARGTNAARGARGARMGNMGNTTYYTNYTNMGNAARYTNYTN CARTTYCARTCNTTYAGYGARAAYGGNGGNGGNTCNATGAARYTNGARGTNCARATGCCN YTNGGNMGNAGYACNAARGCNTCNGCNCARGARGGNTCNAGYYTNGARCAYAAYCCNAAR TCNAARGCNGCNAARMGNAARATGAAYTCN---------------------TCNGGNGGN GCNGGNCAYAAYYTNGGNGGNATHGTNTCNTCNYTNTCNTCNACNTCNGGNGCNGCNTCN TCNGARAARAARMGNAARCARCARCAYTCNGCNAARGAYATHYTNGAYTCNYTNCARGGN MGNCCNAARAARAGYAARTCNGGNGGNAARAARGTNATHCCNCCNYTNATGYTNGAYCCN YTNGGNMGNCCNATGATHCCNATGGTNYTNGGNGAYGTNACNYTNCAYAGYATHGGNGAR ATHGTNACNGAYMGNYTNAGYTTYCAYTGYCCNGARTCNATHTAYCCNGARGGNTAYTGY ATHACNMGNGTNTAYGTNAGYYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGAARTTYACNGTNGARTTYGTNYTNGCNTCNGGNGGNMGNYTNGGN TGYATHTCNCARACNGGNAARCAYGGNAAYTTYACNYTNGARACNCCNYTNTGYACNYTN TTYACNAARGGNGGNAGYGCNCCNTAYYTNAGYAARGCNATGYTNGARMGNATHGGNMGN GTNCCNGAYATHGCNGCNATHAGYATHAAYAAYYTNTGYGARCAYCAYGARAAYGTNAAR CARTTYGGNCAYGGNYTNGGNGAYTTYGTNGCNATGGARAAYAARYTNATHTTYACNACN YTNCAYGAYGCNAGYGTNGGNYTNACNTCNGGNAARAAYACNAARTCNGGNGTNGCNGTN TGGAGYAARAGYGGNAARGTNCARYTNGAYCCNMGNGTNTAYATGAARATGCARGARGCN TTYCARCCNCAYTGGTTYCARGCNYTNAGYGAYGGNGAYACNGAYGARACNTGYGGNMGN AARMGNYTNACNAARGCNGTNGAYMGNACNYTNGAYTTYYTNGAYGAYATHGTNGARYTN MGNGARAARAGYGARTGYYTNAARAAYTCNAGYYTNATHGGNGTNATHGARGGNGGNTTY TCNGARGARGARMGNAARMGNTCNGCNYTNGARACNGCNGCNMGNCCNGTNCARGGNTTY YTNATHGARGGNTTYGARAARGGNTGYACNGAYAARGAYGTNTTYAARCARGARGAYTTY ATHCCNACNYTNAGYAARACNATHTCNTTYYTNCCNGARGAYAARATHMGNATHATGGAR TCNACNTGGTCNCCNYTNCARGTNATHMGNGGNTTYMGNYTNGGNATHGAYGTNTTYTCN AGYTCNTAYCCNCAYACNYTNACNGARAARGGNTTYGCNATGGCNYTNGAYTTYTCNYTN CCNTCNAARTCNGARATHGCNAAYTCNGARAARGAYGGNTCNGAYCARAAYAAYGARACN GAYGCNTTYTAYYTNAAYYTNAARGAYAARMGNTAYTTYGARGAYTTYTCNCCNYTNGTN GGNGGNTGYCARTGYTAYGCNTGYGCNAAYTTYACNMGNTCNTAYYTNCAYCAYYTNYTN ACNACNTCNGARYTNCARGCNTAYATHYTNYTNACNATHCAYAAYTTYCAYATGTAYTTY GARTTYTTYCARGCNYTNMGNGAYGCNATGMGNAAYAARMGNYTNGAYCARYTNGARGAY ACNATHACNAARCAR---GCNYTNGTNTTYTAYACNATHGAYGAYATHMGNMGNTGGCAR TTYMGNAAYGGNACNATHYTNGTNTGGYTNYTNTGYAAYATHGCNTGYATHTTYYTNACN CARGCNGCNACNTTYTTYTGYGTNTCNTGYGTNGTNATHGGNATHGCNACNYTNTGYYTN TTYCARGTNCAYACNMGNATHYTNGAYAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATHTTYGARACNCAR--------- ---------------------CCNTTYACNCCN--------------------------- ------------------------------------------------------------ ------------------------------MGNGTN------------------------ ---------------------------------AARGTNMGNYTNACNCCNTGYCARTGG GARGAYACNYTNGTNYTNCARMGNGARGCNGCNCARCARAAYCAYYTNGAYGTNACNTAY GTNTTYCAYAARATGGTNCARGARCAYGCNTTYCAYTTYTGYTTYACNAAYGARGARATG AGYACNMGNACNAAYAARGCNGARATHGARAAYAGYGARAARAAYATGGCNGAYGAYYTN AARGARGARMGNMGNGAYATHAAYTCNYTNTTYAAYTAYGARTCNATGGARCARYTNTCN TAYYTNYTNGAYCAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNGTNTGYGTNMGNATGACNYTNGCNATHGGN TCNATHTTYYTNGCNYTNTTYTCNYTNGTNGTNCARGCNMGNYTNTAYTTYGAYTAYAGY ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARCCNAARMGNGGNGGNATHAGYTTYGAYGTNATHYTNAARCCN GCNTCN------ACNYTNMGNCCNCCNAARCCNYTNTCNCCNAARGAYAAYAARCARMGN GAYTTYTCNCARGARGARATHTCNACNAARYTNAARAARGCNGARCARMGNAARAGYYTN ATHGARMGNGARMGNYTNGAYCARYTNGCNAARGARMGNCARMGNGCNATHGARGTNATG GCNAARGCNCARTGYGARAGYGARGARTTYTCNAARAARACNGARGARAARYTNMGNMGN TCNATGGARATHMGNMGNGARAAYMGNGARACNCARATHMGNGCNYTNCARGARMGNYTN MGNGARCAYTCNGTNAARGTNCAYGARGTNCARAARTCNGGNGAYGARATGGTNAARAAR TTYGARGCNAARGCNGARCARAARYTNTCNCARAARATGGGNACNTAYGARGARAAYMGN GARAAYCARYTNMGNAAYATGYTNTCNAARYTNCARGARCAYAARATHAAR---AAYCCN AGYGARGTNGCNTCNGCNYTNATHGARGARTTYTCNAARAARACNGARGARAARYTNMGN MGNTCNATGGARATHMGNMGNGARAAYMGNGARACNCARATHMGNGCNYTNCARGARMGN YTNMGNGARCAYTCNGTNAARGTNCAYGARGTNCARAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNMGNGARATGATHATHGARATHAAR ACNAGYYTNYTNCARAARYTN---GARAARGGNTGYAAYACNTCNGARYTNGCNYTNGAY TTYACNAGYTCNYTNYTNTCNCAYTAYGARYTNTGYACNAARAARGCNCAYYTNYTNGCN CARTAYYTNGGNGGNYTNACNGAYCAYYTNAARCARTTYCARGTNACNTGGGARYTNYTN AAYAARCAYYTNTTYCAYTCNATHGCNCAYAAYGAYCCNGCNATHAGYAAYAGYGGNCCN CAYATHYTNGARCARYTNMGNCARGGNTCNYTNMGNTAYGARMGNTCNMGNGAYGAYCCN TAYTGYACNGTNMGNAARTGYYTNYTNAARTTYCARGARGARATGTCNGTNGTNGTNGTN GTNTGGMGNGAYTGYCARYTNYTNATHGARAAYTAYTGYCARGARGARGTNAARAAYACN CARAARCARGTNTCNAGYAARGCNMGNAGYTTYATHTCNCARCARMGNCARTTYYTNAAR GAYCAYYTNATGAARGAYTCNTTYATGGAY---GARACNATGAARAGYYTNYTNTCNGGN CAYAARTCNTCNACNGARMGNGARATGTGYMGNMGNTGYAARMGNGARMGNTGYACNTGY GAYGARTGYACNATHACNCAYATGATHACNTGYGGNATHATHAAYACNGARAARGGN--- GGNATGCCNTCNCCNCCN---TGYTTYAAYTTYGCNYTNGAYCCNGCNCAYAGYGTNYTN GAYATGACNCCNCCNTCNATGTCNAGYACNACNTCNAGYAGYGGNTCNGTNTCNCCNATH AAYGTNGARGAYAARAAYTCNCCNTAYGAYTGYGGNMGNACNGAYGCNATGYTNACNYTN GAYGAYYTNATHGAYAAYATHGAYGGNGAYACNGGNGAYGAYGARGARGAYGAYATHGAY GAYGARGAYGCNTAYGCNGAYAAYCARGARGGNAGYGAYGARCCNCAYGAYATHCARTTY CARCCNMGNYTNGAYAGYCAYYTNTCNMGNCARYTNGARGCNGARYTNGCNAGYTCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATHAAYYTNCCNYTNAAYATHMGNCAY AARTTYGGNAGYMGNGTNTGYGAYACNYTNYTNTCNGAYCARGARYTNGTNTCNTCNGCN YTNGARMGNCARCARYTNGARTCNGGNCCNCCNMGNCCNTCNAARAARTAYCAYGTNAAY CCNYTNCCNGTNGAYATGAGYMGNAAYTAYGCNTTYYTNGGNCAYACNACNMGNTAYAAY ATHTGYCAYGGNATHAGYTCNGGNCAYACNATHAGYCARACNCARYTNGARTTYAAYGAY GARGTNCAYYTNMGNMGNGTNCCNAAYCCNGAYGARTTYMGNTAYCARMGNGAYGARYTN AGYACN---TGGTCNGARCAYAAYGTNYTNMGNGARMGNATGAARAARGCNTGG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GGN TTYYTNTCNTTYGTNGGNATHATHATHTTYATGATHATGACNTCNGARGTNATHTCNCAY GGNGCNTCNTAYTCNTGGGGNTTYGGNTTYTCNTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TAYGAYTTYTTYGTN AGYGARGTNAARAGYYTNCARCARAAYTTYCCNAAYCARAGYMGNAGYYTNTGGAARACN GTNGCNTCNTCNACNMGNCAYATHTTYACNCARCCNGAYCCNAAYTAYCCNTCNGTNATH YTNYTNGCNTCNCARTCNGCNGCNCCNGTNYTNAAYTCNTGYATHGCNAAYAARATHGCN TCNGTNTTYYTNAARTCNMGNGGNYTNCCNGTNAAYGCNYTNTCNACNAAYGTNGAYCAY YTNAARCAYYTNGGNGCNGCNGAYCARAARYTNGARYTNGAYAARGCNGTNAAYTCNGCN TTYMGNTCNTCNGGNGARAARGCNTAYGTNATHAGYAAYYTNCARTCNYTNTCNCCNGAR GCNGCNYTNYTNYTNCAYAGYYTNTGYGAYGGNGAYAAYGCNCCNTTYAARGAYGTNATG ATHGTNYTNACNYTNCARGTNGARAAYGGNMGNGTNYTNATGAGYGCN---------AAY GAYATGGARGAYTAYYTNACNMGNYTNTGGACNAARCARYTNCAYTAYGAYAARGTNACN GCNYTNATGAGYMGNATHGCNAAYAAYYTNGTNGTNYTNYTNGARGARGAYTCNACNGTN ATHGARCARATGTGY--------------------------------------------- ------------------------------------ATHYTNTCNATGGARGAYGCNAAY GAYYTNGAYGAYTAYATGCAYGGNTTYYTNGAYGAYACNGAYCCNAARGTNMGNACNTTY YTNCARGARYTNMGNAGYMGNTCNATHGCNATHMGNAAYMGNGARAAYATHCAR------ ---AARAAYTCNCCNGARGTNATHTCNTCNGCNAARCCNAARAARAARAAYATHAGYGTN AGYGGNAGYAGYGAYGAYGGNATGTCNAARTCNTCNCARAAYGGNACNYTNGGNACNTCN TCNTCNGCNCAYTCNCCNATGCARACNCCNAAYCARAAYAGY------------------ TCNGGNGARATHGGNGTNGGNGCNAARMGNAARTCNAARTTYGTNTCNYTNTAYGGNAAR GARGGNCARGAYAARTCNGTNATHCARATHCCNGGNMGNCAYGTNTGYGARTGYCARGCN GCNAARCAYAARATHATHAAYAAYTGYATGCARTGYGGNMGNATHGTNTGYGARCARGAR GGNACNGGNCCNTGYGTNTTYTGYGGNGCNYTNGTNTGYTCNCCNGARGAYCARGARGTN YTNCARMGNGGNTCNAARAARTCNGARAARYTNMGNAAYCARYTNATGMGNGARGGNGCN AARAARGGNAGYYTNAGYGARACNAGYCARTCNATH------TCNTCNTCNGGN---GCN AARTCNAARGAYAGYTTYGAYAARGCNATGAARCAYMGNGAYAARYTNYTNGARTAYGAY YTNACNAGYGTNCARMGNACNCARGTNATHGAYGAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TGGAARAAYAARTGY AARYTNTGGGCNACNGCNGAYGAYTCNYTNTAYAGYCARAGYGCNACNGCNCCNGCNCCN TCNAARAAYTTYGTNCARGTNTAYATHACNTAYAAYCARATHGTNTTYMGNATHTGGAAR ATHYTNCCNCCNACNMGNTCNGAYTCNGCNCARTGYCCNATHGARYTNAARAGYACNTAY CARGARTTYCCNTTYGAYGARMGNATGMGNMGNGARATHGARTAYAAYYTNGGNTGYMGN GARYTNAAYTAYATHGAYCARYTNATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARATHAARGGNGCNMGNTCNYTNATHGCNAAYGAYTAYYTNACNGTNCARGTNACN AAYGAYCCNGTNGARGGNCAYTCNGAYGCNACNGCNACNAGYAARYTNACNGTNATHGTN AARGCNAAYCCNGARTGYACNACNAARGAYTTYAARACNTAYCARGCNCARTCNAAYGCN YTNCCNGGNACNTTYGARGAYGGNGGNGTNTAYTAYGGNCCNTAYAARGGNYTNGARYTN GTNGARGTNGARCCNGGNMGNCAYGTNGARATHCARATHMGNTAYATHGARACNGTNGTN GTNATHMGNCARATHGGNMGNTAYTTYACNTTYGCNATHAARATGCCNGARGARYTNYTN AAYAARAGY---ACNAARACNCCNCARYTNTGYATGCARGGNTGYTCNGCNATHGARCAR ATHAAYTAYCARGAYTAYYTNTCNMGNMGNAARTCNTGGGAYTAYGCNGARAAYGCNTGY MGNGARGCNGAYYTNGTNGGNTTYTAYTTYGAYTCNTGYGTNTTYGAYYTNMGNATGACN GGNGAYYTNAAYTTYACNYTNTCNGCNYTNAGYTCNYTNCARGAYATGYTNAARYTNCAY CCNAGYGCNYTNCARACNATGGCNAAYCARTCNTGGYTNGARMGNTAYCARGAYAAYGGN CAYAGYGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TAYTGGCAR GCNTTYYTNGTNTCNTTYYTNATHACNTTYTCNTGGTCNATGGCNYTNGCNYTNATGAAR ATHTAYCAYACNGARYTNYTNGARTTYCCNGTNGTNGCNGTNYTNGARGAYACNAAYGGN AARACNYTNCCNGAYGCNYTNGCNTGYTCNTAYTCNCCNYTNYTNCARCAYYTNGCNTAY TAYGAYTTYGCNTGYYTNAGYAARTGYYTNCCNATHMGNYTNCARGARYTNYTNAGYYTN AGYCARCCNGGNGGNCAYCCNAARACNTGGGCNTCNGTNAGYGAYTCNGCNTTYACNGAR YTNTGGAARYTNAAYAAYTCNGTNAARGARGARAAYTTYTCNATHATGTCNAARGTNCCN ATH---AGYCARCAYCARAGYGGNATHCCNCAYGTNAGYGGNGTNCCNATG--------- TCNGGNATHGCNACNAAYGGNACNGCNMGNTTYMGNGTNACNGARGGNACNTCNCARAGY AAYGTNCARAARGGNGGNYTNATHTCNAARTGGACNMGNTTYTCNYTNAAYTTYCCNYTN YTNTCNCARTTYYTNGCNCARACNCCNGAYGCNAAYAGYMGNMGNYTNTTYGCNGAYTGY CARGTNCARATHTGGGCNATHCARGGNYTNTCNMGNGTNGCNGTNAARTCNTAYTCNGAR GAYMGNTAYGGNGTNGTNCARGGNACNYTNCCNGTNYTNTTYGCNTCNYTNYTNGARYTN AAYGARTCNYTNGARAARCAYTTYAARYTNACNTCNACNGTNTCNMGNMGNCARAAYGGN TGYTCNATGCCNTCNGAYGTNAARYTNMGNTTYAARYTNCAYTCNGTNYTNAARGCNTCN YTNTAYAGYYTNGTNATHCARTAYMGNGCNCAYYTNCAYGAYYTNAAYYTNAGYCCNGAY GAYATHAARAARYTNACNCCNTTYATHGARTTYGTN------------------------ ------------------------------GTNCAYTTYGGNYTNGTNATHTTYGGNTTY ATHTTYGCNYTNGCNACNYTNATHGGNCARTGGGTNAARCCNGCNCCNTAYGGNAARCAY GARMGNATHGAYCCNAAYTGGGGNCCNYTNATHCCNCARMGNYTNAGYCAYATHATHTCN GAYGCNYTNTCNGGNGTNYTNATGTTYTCNYTNMGNTAYTAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TGYGAYATHGAYMGNATHACNGTNGCNGAYYTNMGNCAYAARTTYGARMGNYTNAAR AAYMGNAARYTNACNGTNGARGARAARMGNGTNTTYTCNAAYAARTGYCARACNTTYATH TGYGAYYTNYTNGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------GGNTTYATHYTNCAYCCNTCNGGNACNCAYTAYATGCCNATHTCN GTNCAYAAYACNAAYATHTCNGARYTNYTNGARTGYAAYGGNGARCAYGAYGGNGCNCCN GTNTTYCAYCCNATHAGYATHCCNGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARGARGARGTNCCNGAYAGYACNCCNGCNAAYGARGARTTYGTNAGYGAY GCNTTYGGNGAYAGYCARATGACNGARGARGAYATHMGNAARGARATGGARCARCAYATH MGNGTNGGNGARGGNCCNAAYAAYTAYTGYTAYYTNTGYTCNACNYTNGAYGARCAYCAR CARCAYYTNCAYCARATGMGNGTNCCNMGNAARACNGTNACNAGYAARCCNMGNATHYTN TAYCARGTNCCNYTNCCNAARGTNAARTGYAARAARGARGARGARAARGARGTNTAYACN GARMGNTAYAARATHGTNATHTGGACNGGNGAYGTNCCNGAYGCNTCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARAARAAYTCNAARYTNAARYTNAARAARAARYTNTGYATGTTYTTY TGYMGNTTYGGNAARTGYGARMGNGGNGAYGCNTGYCCNTTYGTNCAYGAYCCNAAYAAR GTNGCNGTNTGYACNMGNTTYYTNMGNGGNAARTGYGAYACNGCNAGYTGYCCNTTYTCN CAYGAYGCNTCNGTNCAYAARATGCCNGTNTGYYTNTTYTAYYTNMGNGGNYTNTGYTCN MGNGGNGAYTGYMGNTAYYTNCAYGTNAAYGTNAAYCCNGAYGCNCCNGTNTGYAARGAY TTYMGNCARGGNTAYTGYTCNYTNGGNAARAARTGYAARAAYYTNCAYTCNTTYGTNTGY CCNTCNTAYGCNGTNTTYGGNAARTGYTCNMGNGGNACNAARTGYTCNYTNYTNCAYCAY MGNCCNAARAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GGNYTNAGYGARMGNACNTCNGAYYTNCAYMGNYTNACNYTNTCNYTNGCNGGNAAR AARTGYACNCCNGAYCARACNCCNGAYAAYTGYCCNGCNTCNGGNYTNGCNAGYGGNYTN GTNAARGCNTGGGARYTNTAYGGNAAYCARAARGCNGTNGTNGTNTTYATHGTNAGYYTN AGYGARMGNAAYGARATGGAYCARMGNGCNYTNGARTTYGGNGTNTAYAARCARAAYCCN AGYATHMGNGTNYTNMGNMGNACNYTNYTNGAYTTYCAYTCNMGNGGNAAYGTNGAYGAY GAYGGNYTNYTNACNATHGAYTGYGAYGARGTNGCNGTNYTNTAYYTNMGNGAYGGNTAY ACNTCNGARAAYTAYCCNTCNCAYAARGARTGGGAYGGNMGNYTNAARATGGARYTNTCN MGNGCNYTNAARTGYCCNTCNATHCARCAYCARYTNGTNGGNGCNAARAARATHCARCAR GARYTNGCNMGNCCNGGNGCNYTNGARYTNTTYYTNTCNGAYCCNAARGTNATHCARGAR YTNMGNGAYACNTTYGCNGGNCARTAYAGYYTNGAYYTNGGNYTNGAYGGNGAYACNGCN GTNGCNYTNGCNYTNGCNGAYCCNGAYAARTTYGTNYTNAARCCNCARMGNGARGGNGGN GGNCAYAAYYTNTAYAGYGARGAYATHGCNCARTTYYTNAARCARCAYGCNACNAGYAAR GARMGNAAYGCNTAYATHYTNATGCARMGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GGNTGGACNGGNTCNAAYTGYTCNGTN CCNTGYGCNGGNGGNTGGTTYGGNGAYAAYTGYTCNCARCCNTGYYTNTGYTCNMGNCCN GARGARTGYGAYAGYGTNACNGGNACNTGYCARTGYMGNCCNGGNTAYACNGAYAARTAY TGYCARAARMGNTGYCCNTAYGGNTTYTAYGGNCARGAYTGYTCNGARATHTGYTTYTGY AARGAYAGYTGYTTYTGYGAYCAYGARACNGGNAGYTGYAAYGTNTCNCAYATHAGYATH GAYTAYATHAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYCCNGARGCNCCNCCNGARTAYAARGARMGNACN AAYGTNTCN------TCNGARAARCCNCCNTCNTAY------ATGGTNTCNGARAAYGAY CCNCCNCCNACNTAYGARTCNYTNTAYGGNMGNGTNAARGCNGCNAARTCNGARGCNAAY GGNTTYYTNTCNTTYATGAARAGYTTYGTNATHATHATHYTNTCNACNATHGGNTTYACN ATHYTNGTNGGNATHTTYATGGCNGTNCCNGTNTCNATGATHGTNATGGGNTCNATHCAY YTNGAYGAYTGYCCNGCNGARMGNATGATHCCNATHTAYYTNATHGTNTCNGGNTGYTTY GGNACNATGAARAAYYTNGTNAGYYTNATHGARMGNTGYMGNAARAGYGARGARGARMGN CARGARGAYCARAARAARGTNAAYCCNATHGAYAGYYTNGTNAAYTGYTTYYTNTTYGTN TGGTTYATHGCNGGNTGYGTNTTYATHTAYMGNACN---AARGAY------CARATGCAR ACNCAYACNAAYGGNAAYTAYTGYGAYTTYTCNYTNTAYTGGTTYGCNTTYTGGATHACN ACNGCNGTNTAYATHATHATGGCNATHAGYTGYTGYTGYGTNGCNYTNGGNGGNTGYYTN GCNACNTGYATHGTNGAYAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GCNATHAAYGARACNGAY GARGGNCCNAARGAYGCNATHMGNGCNTTYMGNAARMGNATHTCNCARAAYGTNGGNAAR AAYTAYATHTGYGTNATGCAYTGYYTNACNGGNATHGARTCNTGYGTNAARAAYTGYGGN MGNMGNTTYCAYYTNCARGTNGCNAGYAARGAYTTYYTNCAYGAYYTNATHAARATHATH GGNCCNAARAAYGAYCCNCCNCARGCNATHCARGARAARGTNYTNAGYATGATHCARACN TGGGCNGAYGCNTTYMGNGGNATHCCNGARYTNAARGARGTNGARAARGTNTAYCARGAR YTNAARCARAARGGNATHGARTTYCCNATGACNAAYYTNGAYAAYATGGCNCCNATHCAY ACNCCNGCNMGNAGYATHCCNGARMGNGARCARAGYCAYYTN------GAYMGNGGNGGN AGYAGYMGNGGN---TAYNNNCCNNNNNNNNNNNNNNNNNNNNNNTAYNNNCCNNNNNNN TAYCCNCCNGCNCCNCCNTCNGCNTCNGGNGGNAAYAGYCARGGNYTNACNTCNGAYCAR ACNACNAARYTNMGNMGNGARYTNGAYGTNGTNCARGGNAAYAAYMGNATHYTNAGYGAR ATGYTNACNGARYTNAGYCCNTCNAAYGTNGAYCCNTCNGAYYTNGARYTNYTNCARGAR YTNAAYMGNACNTGYMGNCARATGCARTCNMGNATHGTNGARYTNYTNAAYGGNATHGCN ACNGARGARGTNACNAAYGAYYTNYTNMGNATHAAYGAYGAYYTNAAYAAYGTNTTYYTN MGNTAYGARMGNTTYGARMGNTAYMGNACNGGNCARTCNGGNCARTCNACNACNCCNTCN ACNGARGAYCCNCCNCARGAYYTNCCNCCNCCNTCNTAYGAYCARYTNCCNGCNTCNAAY AAYCCNAARGTNGGNAAYYTNATHGAYYTNAGYGAYGAYCCNGCNCCNGTNAAYAAYGCN ATHAAYTCNCARYTNGCNGAYYTNTCNATHAAY---------------------CCNGCN CCNGCNCARGGNAARGCNGAYGAYGAYTTYGAYATGTTYGCNCARTCNMGNCARTCNTTY GAYCARAGYMGNCARGCNYTNTCNACNACNTCNTAYGAYAAYCARCARGTNGAYACNTAY AGYGGNGGNYTNGGNCARGCNGTNAGYGCNMGNACNAAYGARGAYGCNATHAARYTNCAR GARAARGARACNGAYTAYGAYGARATGGARCARTGGYTNGCNACNCAYAGYGCNGTNCAR GCNGAYTCNCARCCNCARGARCCNATHACNAGYTCNGARTTYGAYMGNTTYYTNTCNGAY MGNACNACNGCNTCNGAYACNYTNCCNAGYATHTCNGCNCARACNGGNMGNTCNACNMGN ACNYTNCARAARMGNGAYGAYGAYGARAAYCCNYTNTTYGCNYTNAARGCNTCNTCNGTN AARTCNACNAAYCCNTTYYTNCCNGARMGNCCNCCNAAYCCNCCNCCNYTNAGYTCNGCN MGNAGYTCNTCNYTNMGNGCNAARGCNCARGARAARGAYACNGGNGGNCCNCCNCCNYTN ACNGCNAARCCNAARAAYCCNTTYYTNAAYGAYGARATHCCNAGY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARGGNAAYGGN CAYGCNMGNGAYYTNATGGARGARMGNMGNGTNTAYATHYTNGAYATHTAYAAYMGNGAY ATHTAYCCNCAYGAYGGNTTYGCNAARMGNGCNATHAARMGNAARGTNGARYTNMGNTCN TTYACNAAYACNGAYACNTAYYTNGARYTNGTNGAYMGNCAYGTNGARGGNGCNYTNAAY GARTTYGARCCNCAYTTYGTNGCNTAYAAYGCNGGNACNGAYATHYTNGAYGGNGAYCCN YTNGGNAAYYTNTCNGTNAGYGCNGARGGNATHATHAARMGNGAYCARATHGTNTTYGAR AARTGYMGNAARMGNAAYATHCCNATHTTYATGGTNACNAGYGGNGGNTAYATGMGNGAR ACNGCNMGNATHGTNGCNGAYTCNATGYTNAAYYTNMGNMGNYTNGGNYTNATHTCNTGY GARGARGCNGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNTAYMGNGCNGAYGCNATHATHACNGAYACNTGGGTNAGYATGGGNCARGARGAR GARAAR---AARMGNMGNYTNCARGAYTTYAARGGNTTYCARATHGAYMGNCARATGYTN CARGARGCNGGNGGNGAYTGGGTNTTYYTNCAYTGYYTNCCNMGNAARCARGARGARGTN ACNGAYGGNGTNTTYTAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GCNTGGAARTTY ACNCCNGAYAGYCARACNGGNATGMGNYTNATGGCNAARTGYMGNATGYTNYTNCARGAR AAYGGNGARYTNGGNAARATGATHTCNTCNGGNMGNACNGCNMGNYTNGARGGNGARATH TCNYTNCARAARGCNYTNGTNGTNGARATGAARAARAAYCARAARGARYTNGAYGARTTY GTNGGNGARYTNGARGARGAYGTNGAYAGYATGCARGGNATGATHTTYATGYTNCARCAR CARYTNAARGARGCNAARGARCARATHTCNAARYTNCARCARGARAAYGTNTGYYTNMGN ACNYTNAAYGTNCCNGCNGARCAYGARCCNGGNGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARTTYGARCCNGCNGAYYTNGAR GARGARGARGGNACNTGGGTNCARTGYACNAAYAARYTNTGYGARAARTGGMGNTAYGTN TCNGAYATGTAYGAYCCNATHYTNGTNCCNGAYYTNTGGGARTGYAGYATGAAYTCNGAY AARAGYCAYAAYTGYTGYGAYGAYYTNGARGARATHTAYGAYGARAGYGARCAYATHYTN ACNAARTAYACNGTNGGNTCNGTNGTNTCNGCNAARATGGAYGGNTAYCCNTGG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ACNCCNGAYACNGCNGAYYTNGARGAYTTYGTNYTNMGNCCNGCNCCNCARGGNGTNACN ATGAARTGYMGNATHACNMGNGAYAARMGNGGNGTNGAYMGNAAYATHTAYCCNACNTAY TTYYTNCAYYTNGARCARGARAAYGGNMGNAARACNTTYYTNYTNGCNGGNMGNAARMGN AARAARAGYGCNACNTCNAAYTAYYTNATHTCNTAYGAYCCNACNGAYYTNAGYMGNAAY GGNGARTCNTAYTGYGGNAARYTNMGNTCNAAYYTNATHGGNACNCARTTYACNYTNTTY GAYCAYGGNGAYAAYCCNAARAARAGYGAYGTNYTNGGNGCNMGNCARGARYTNGTNGCN TGYGCNTAYGARACNAAYGTNYTNGGNTTYAARGGNCCNMGNAARATGACNGTNATHATH CCNGGNATGACNAGYGAYCAYATGMGNGTNAAYATHAARCCNGTNGGNAGYAAYGAYGGN YTNATHGARMGNTGGAARAARAARAAYATGGARAAYYTNYTNGARYTNCAYAAYAARACN CCNGTNTGGAAYGARGAYACNCARTCNTAYGTNYTNAAYTTYCAYGGNMGNGTNACNCAR GCNTCNGTNAARAAYTTYCARATHGTNCAYGAYAAYGAYGTNGAYTAYGTNGTNATGCAR TTYGGNMGNGTNGCNGARGAYGTNTTYACNATGGAYTAYAAYTAYCCNATGTGYGCNYTN CARGCNTTYGGNATHGCNYTNAGYAGYTTYGAYGGNAARYTNGCNTGYGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNGARAGYATHYTNAGYCARTCNCAR YTNMGNTTYCCNAAYCAYCARGAYGTNTGGYTNAARGAYYTNGCNTCNTAYYTNAAYATG AARYTNGARAAYGTNAGYGARACNGAYCCNATHTTYAARGGNAARCCNAARGAYTAYCCN YTNCARGCNGTNCCNGGNGCNTAYGARAARYTNYTNAAYGCNTTYATHAARAARTTYTCN GAYTCNYTNYTNGAYCARATHTTYTAYTAYGGNATHATGACNATGGTNCARGARTCNGTN AARGGNAAYCCNGTNTAYGGNTAYAARYTNTTYYTNCARYTNYTNGCNCAYAAYAARCCN GAYATHGCNATGGGNAARGTNCAYCARTAYYTNGARYTNYTNAARACNTAYCARAAYAAY CCNGCNMGNTGYGTNTCNATHYTNTGGGCNYTNGGNCARTGYGGNGTNAARAAYTTYAAR TGYGGNYTNAARGTNTGGYTNGAYYTNATGYTNCCNGCNYTNGARGTNMGNCARGTNGCN TTYTAYCCNGTNGARTAYYTNAARCARYTNYTNAGYAGYCAYAARAAYAARGCN---AAY ------------GGNTAYGGNGTNGTNACNYTNMGNGARTAYTTYCARGTNYTNGAYGTN GTNTTYAGYCCNAARTTYAAYYTNGCNAAYGAYYTNMGNAARMGNYTNACNATHYTNTAY CCNTTYATHAARGARATHGCNTAYGGNGAYACNCCNTCNCAYAAYYTNMGNACNTTYTTY CCNTCNTAYYTNGCNMGNTTYACNTCNTCNACNAGYGARGCNGTNAARGCNGARYTNYTN GARTGYATGACNACNTGYYTNACNACNGAYAARCARTCNTTYAGYGTNTGGTGYCARYTN TAYACNAARCAYYTNCCNGCNTCNGGNCAYYTNYTNGARCAYATHAGYTAYGARTGGCCN AARCARTCNTCNAARTTYGAYCAYCARYTNYTNATHAARACNYTNGGNTCNTTYTCNGTN ACNAAYGARGARATHGARACNCARAGYAARGGNCARMGNGAYGGNTTYGGNYTNTGYCAR GCNGCNACNAARGAYYTNYTNGGNAARYTNATGGGNAARCARTTYCCNTGGAGYATHYTN ATGTTYTTYYTNATHTCNGCNATGGCNTCNATHGTNGTNTAYGAYYTNGTNTCNAGYCCN AAYYTNCCNATGTCNMGNACNATHMGNTTYYTNGARCAYTAYGGNATHYTNGCNYTNATH GARCARGCNTGGAARCAYGTNTAYACNTTYATHTCNGTNTCNGTNAAYTGGATGMGNATH AAYGTNCCNGTNTAYTTYGCNTGYACNTGYGARACNYTNGGNCCNCAYYTNAGYTTYGCN TGGGARMGNTCNAARACNTTYGCNGCNAAYGCNGARYTNGTNACNCARCCNCAYMGNGCN TGGYTNATHGAYAAYGCNATHAARTTYTAYTAYTGGGTNTAYGAYYTNTCNCCNGARTCN TGGACNTGGTGYGGNGARATGYTNTGYATGGTNTGGGARYTNGCNAARGGNTAYACNYTN MGNATHTGGAARCAYTCNCAYCAYYTNTCNGARGAYGCNTAYYTNTGGTTYACNAARAAY ATHYTNACNTCNACNYTNTGGAARCARAAYYTNAARGAYACNGCNGTNTGGGGNATHGAR CAYATHCARAAYTGYACNTCNTCNYTNATGACNTGG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGYTNTAYGAYTGYCARAARGTNTTYTCNGCN YTNCARAARTCNGARGARATHTCNGCNGAYTAYGARTGYATHATHACNTCNGCNGCNAGY GTNCARAAYGARCAYGAYCARGARAARGARAARTCNATHYTNATHAARCARATHAAYGAR MGNATGAARCARACNGARGARGTNTCNTCNAAYCAYAAYCAYGTNACNGGNGTNYTN--- ---------GGNTCNYTNTCNGCNAARAARGCNGCNCARAAYAARGTNTTYAGYYTNATH CARGARGARYTNGAYCAYYTNCAYAGYCARCARAAYATGCAYAARGTNCCNGARAAYGGN GTNGCNGAR---GCN---AARATHCARMGNYTNAAYTCNGARGAYYTNATGTTYAARCAR CARYTNGGNATGGARATHACNAARATHAARGGNGGNTTYYTNCARTTYGCNTAYAGYCAR ATHCAYCAYAAYAARCCNGARGAYYTNTAYYTNTTYTCNYTNAAYYTNGAYCARAAYMGN ACNTAYCARGTNTCNGAYTGYTCNCCNCCNGTNCCNGAYATGGARAARATHGTNGARMGN YTNAAYAGYAAYAAYGAYTTYCAYAARTTYGTNCAYACNATGMGNAAYMGNTTY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GCNGTNATHAARGGNACNAARYTNGCN GARGARCAYATGMGNAARGAYAARGGNGGNAARGGNGGNMGNATHATHAAYATHAGYTCN ATHGTNGGNYTNGAYGARACNTTYCCNGTNCCNACNTAYTCNGCNTCNAARCAYGCNGTN MGNGCNTTYACNTCNTCNYTNGCNAARCARCCNACNYTNGARGCNMGNGCNATHGARTAY GGNGTNYTNTGYCCNGGNGTNGCNAAYACNGARYTNGTNACNAARGCNGAYGGNGAYAAR ATHATGCAYTTYGAYYTNATHAARCAYGCNYTNYTNCARGAYCCNYTNCCNGTNTCNCAR GTNGTNGARGGNTTYYTNAARYTNYTNCARYTNGARAARATGAAYGGNGCNATHYTNMGN GTNMGNAARMGNCCNTAYAGYGARYTN------ACNGAYCCNTAYGCNGGNCCNGARGAR TTYATGGARGCNGGNGTNMGNGGNTTYYTNGTNACNTCNATHCCNAAYMGNGARGARCAY GCNGTNGAYCARGCNYTNAARATHYTNMGNAARGCNTCNGTNAARYTNTAYGGNGGNATH ACNCCNGGNAARAAYAGYGAYGCNTCNTTYGCNACNGGNTAYATHGCNGTNGAYTTYATG GARCCNGARACNGTNCAYTTYYTNCCNAAYCCNAAYGTNGAYGCNGARGARGCNGARCAR GAYCARCARGARTCNAARGARAARGARACNGARGGNGAYCARACNGARGCNACNCARCAR TCNGARAAYAARGARATGGGNAARACNGARGARAARATGGARACNAARAAYAARGAYAGY ---GAYGARAARCARGAYGARGGNAARGARGARGARGARAARTCNGAYAAYAARGAYGTN GAYGARAARATGGAYGARTCNGARGARGGNGARGARAARGTNGARGARAARGARAAYGAR GCNGARGCNGGNAARGAYGAYAARTCNAARGAYGARTCNTGYMGNTCNAARAGYAGYGAY GGNGGNGAY------------AARAARAAYAARGAYGGNAARAARAARTCNAARGARGAR GARMGNACNCAYAARTAYCCNYTNATGAARACNCAYCAYAARTTYGARGCNTTYMGNACN GARYTNMGNAAYATHATGTTYATHAARTCNGAYGTNCCNAAYCCNAARGAYYTNGTNTGY GARATHATGGAYYTNATHATHGCNAARCARCCNYTNAARGGNGAYTGYGTNAGYMGNYTN YTNCCNATHCAYGGNGTNTGYAAYTTYGAYTTYTGGGARYTNGARATHATGTCNAARMGN GTNYTNGCNCCNTTYTTYCCNGARGAYGTNGARGARGCNCCNAGYTTYGGNATHYTNYTN TTYGAYAARYTNAGYGARCCNGGNTCNGAYAGYYTNGTNGARATHGTNMGNAGYGCNATH TGGTCNATGAAYCCNYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNGARGCNGTNATHCAYGCNTGYGCNAAYGTNYTNCCN GTNGCNGAYMGNTTYYTNYTNAARGAYYTNGTNCARCAYGTNGCNTCNGTNYTNTCNCAY TCNTGYYTNYTNCCNCAYACNGTNTCNTTYGTNTTYGAYYTNGCNTGYGCNTAYAARYTN GAYGAYYTNGCNGCNGAYTGYGTNGCNGCNAGYTAYACNGGNCAYGARAAYAGYCCNTTY ATGCARAARYTNYTNYTNAARAARGGNGGNAARACNAARAARMGNTGGTAYGARCCNCAY TTYGCNGARCCNYTNGARMGN---CCNGGNAARACNMGNAARGGNTGGTCNCARAGYCAR MGNACNMGNGCNMGNCAYYTNAGYAARGTNYTNTTYGAYAARATHTCNCARYTNGTNGTN TCNGGNGARGTNTGYCARCAYYTNGCNGARATHCARGTNAAYATHGTNGCNGTNACNGTN AAYGCNGAYYTNAAYAGYGTNAAYGTNTAYTGGGAYGCNGAYMGNATGGAYTGYGAYATH ATHGARCARGAYYTNCARGCNCARCARGGNAARYTNMGNAGYYTNYTNATHTCNTAYCAY GTNYTNGGNMGNATHCCNCCNATHGTNTTYGTNAARGCNMGN---CAYTCNCARGGNACN GCNCAYYTNAAYCAYYTNTTYAGYATHGCNGAYTAYGGNCCNGARTAYACNCCNGGNCAR AAYCAYAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CARAAYTGGGTNCCNCCNYTNCCNMGNGGNTAYGARGCNMGNTAY GAYTCNAAYCARGARMGNTAYTTYTTYATHAAYCAYGCNACNAARAARACNCARTGGGAR GAYCCNMGNTTYCCNTCNGCNAGYTCNAAYGCNGCNGCNGCNGCNTCNGGNCAYTCNCAR MGNTCNTCNCARAGYACNAGYAAYCAYCARCARGARGARTCNAGYYTNACNAAYACNGCN AAYATHGCNGTNATHACNAARYTNCAYCARCARTTYCCNAARGCNTCNAARGAYTTYATH YTNGAYYTNTTYGTNYTNTGYCAYGARAAYGARAAYAARACNMGNCARCARYTNAARGAR YTNGGNTTY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CARTTYTAYMGNYTNGGNATGTCNTCNGTN YTNTGGAGYGARATHCAYACNCCNGGNAGYCCNTGYYTNAGYCAYCAYGCNTGYGTNGTN GTNGARGAYMGNTAYATGATGYTNATHGGNGGNTGGAAYGGNMGNAARMGNTGYACNGAY ATHCAYGTNTAYCAYACNCARGARGAYAGYTGGYTNCARATGGARCARMGNGGNTTYATG AARGGNGCNGGNYTNAGYTCNCAYACNGCNTCNATHYTNAGYAAYGGNGAYGTNYTNATH ATHGGNMGNGARGGNAGYYTNMGNACNCARMGNAARCAYGGNGGNGCNTAYATHYTNTCN GGNCAYATHCARTCNGGNCARTTYGTNTAYMGNCARTAYAGYAAYAAYGTNACNTCNMGN TCNGGNCAYTCNGCNGAYGCNATHAGYAAYTCNGTNTTYATHATHGGNGGNMGNAGYGAY AARYTNYTNGARAARGTNCCNGGNTTYMGNCCNTTYGTNCARCCNACNTGYTCNATHYTN GCNACNATHATGGAYGCNATHAAYACNTGYMGNATGTCNCCNGTNTCNAARTAYCCNTGY GGNMGNAARAAYCAYATHACNGCNGCNGAYAAYAARTGYATHTTYGTNCAYGGNGGNGAR ACNTTYGAYGGNTGYAGYMGNGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARTTYGARGCNCARGARGAYGCNAARGTNGCNAAYCARGTNAAR GCNAARCARYTNGGNTCNMGNYTNCCNATGGARGGNCARATHYTNAARTTYACNAAYGTN GTNAARGGNTAYCARTTYMGNTGGYTNGTNYTNGAYCCNGAYTCNGGNATGYTNGARTAY TTYGARAARGARGARCAYAARAARCARMGNCCNMGNGGNTCNGTNCAYYTNGCNGCNGCN GTNGTNTCNCCNTCNGARGARGAYTCNCARACNTTYGTNGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CAYGCNAGYTTYYTNTAYTGYGARATHYTNGTNTAYGTNYTNGGNTTYYTN ACNYTNYTNCAYGCNTTYMGNAGYGGNGGNMGNTTYAARTGGYTNTGGTTYGCNATHYTN YTNCAYGGNYTNACNGTNGARTGYGTNAGYTAYTAYTTYCCNGAYATHGAYAAYTTYTGG CAYGCNCARTCNATGGTNATGYTNYTNGGNCARMGNYTNCCNYTNCAYATHACNATHYTN TAYCAYGTNTTYATHTAYACNGCNGTNGTNGCNGTNTCNCAYYTNAAYYTNMGNTGGTGG GCNGARCCNTTYGCNGTNGGNATHTCNGTNGTNYTNATHGAYATHCCNTTYGAYATHATG GGNGTNAARYTNYTNTGGTGGACNTGGCAYGAYGAYGAYCCNAAYATHTTYGAYMGNCAY TAYTGGGTNCCNTGGACNTCNTAYTAYTTYCAYGCNTCNTTYGCNTCNTCNYTNGCNYTN YTNTTYTTYGGNYTNMGNMGNYTNYTNTGYMGNTCNGGNYTNAARTTYCARAGYGCNGGN TTYTTYTGYGARYTNCCNATHYTNATHATHACNGGNYTNTGYTCNACNCCNYTNGGNATH YTNCARTTYGCNCCNATGTAYCAYATHYTNCAYGAYTCNTAYMGNATHCAYACNGARGTN TGYGTNTTYYTNYTNTTYGCNGTNTAYGTNYTNYTNGTNTGGAGYGCNGAYMGNTAYCCN TCNGARAAYGCNMGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY GAYGARGAYGARTCNCAYYTNCCNCCNGGNGTNMGNAARCARAAYMGNTGYAAYAGYAGY AGYAGYGARGAYGARGAYGARAARATHAARAAYTCNAARGAYGCNGAYTCNTCNTAYTCN GAYTCNGAYAARTCNGAYCAYAARTCNTCNAARAARGARTCNYTNGGNAAYGCNAARMGN TCNYTNAARGARGAYTCNMGNGARAGYMGNGAYAARGAYCCNTCNATHAARGTNAARCAY AGYAARTCNMGNTCNMGNTCNMGNTCNGGNTCNCCNMGNAARMGNMGNMGNTCNTCNGAY MGNAGYMGNCAYTCNMGNTCNMGNTCNMGNGAYMGNMGNCAYAARAARGARMGNMGNMGN MGNTCNCAYMGNTCNMGNTCNMGNGAYMGNMGNMGNTCNMGNGAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CCNACNYTN GCNGTNATHACNGARGTNTCNGAYTCNAGYGARGAYGARGAYTTYAAYAAYATHCCNAAY ACNGCNGGNTAYACNYTNYTNTCNCARGARCCNGGNGAY--------------------- GARGGNGARGARGARGARGAYGTNAAYGTNTCNAAYATGGAYTGYAAYCAYGAYAAYYTN GARTCNCCNCCNAAYAGYGTNAAYGCNGCNCARYTNGAYTCNYTNCCNGARGARGTNATH MGNTCNGARGCNGGNGCNACNGCNCCNAARTCNYTNGCNTCN---ACNTCNTGYCAYCCN GCNTTYYTNCARAAYTAYCCNGAYGGNAARGTNCCNTCNTAYATGCARGTNCCNCCNATH GGNCCNGAYACNAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY GAYATHATHYTNATHCARGARATHMGNGAYACNTCNCARAARACNYTNCAYAAYYTNYTN GCNYTNYTNCAYCARTCN---GAYCAYTGGGCNTAYTCNAGYAGYGAYCCNYTNGGNMGN AGYAAY---TAYAARGARCARTAYGCNTTYTAYTAYMGNAARTCNGTNGTNGARYTNGAR GGNCARTAYCARYTNGARGAYGAY---AARGAYGTNTAYGARMGNGARCCNTAYTCNGTN AARATHAARTAYACNTCNTTYAARACNAAYAARCCNAARMGNATHGCNYTNATGGCNATH CAYATHAARCCNAARGAYGCNGTNTCNGARYTNYTNCAYYTNCCNAGYTCNGTNAARACN GTNYTNGGNGTNTTYCCNGAYGTNAGYGGNGTNATHACNYTNGGNGAYTTYAAYGCNGAY TGYAGYTAYYTNAAYAGYTCNTCNMGNACNTCNYTNCCNATHTTYTCNTCNAGYAARGGN TTYCAYAGYYTNATHCCNGAYACNGCNGAYACNACNGTNAARACNACNACNGAYTGYGCN TAYGAYMGNGTNGTNGTNTAYGGNTCNGGNATHGAYGTNMGNAAYGCNGAYGTNTAYMGN TTYGAYGAYCARYTNGGNYTNGAYGAYAGYGARGCNYTNGCNGTNAGYGAYCAYTAYCCN GTNGARTTYTCNYTNTAY---TTYAGYGTNAAYYTNTGYGCNTGYCCNACNATHAGYGCN GGNACNGCNTTYCAYTTYAAYCCNMGNYTNAAYACNAAYGTNGTNGTNMGNAAYAGYTTY ATHGAYAAYTCNTGGGGNTAYTCNGARMGNGAYAAYGGNATGCCNTTYCAYAARAAYGTN ACNTTYAARYTNATGATHAARGCNGAYCAYCAYNNNNNNNNNGTNACNGTNNNNAAYNNN NNNTTYTGYGANTTYNNNNNNMGNYTNCCNNNNNNNAGYNNNMGNTAYNNNTAYATHGAR GGNNNNGTNGARATHAAYTTYATHCARTTYMGNGGNGGNCAYACN--------------- ---GGNGGNGTNCCNAGYTAYGCNCCNGCNGCNCCNTCNTAYCCNGCNGCNCCNGCNTAY NNNNNNNNNNNNNNNNNNNNNNNNGCNNNNNNNNNNCCNNNNNNNNNNNNNTAYCCNNNN NNNNNNNNNNNNCCNATHTAYNNNCCNCCNGTNCCNTTYNNNNNNNNNNNNCCNNNNNNN NNNNNNNNNGGNNNNATHNNNNNNATHNNNGGNNNNCCNNNNNNNAAYCCNNNNMGNTTY ACNGTNAAYYTNNNNTGYNNNCCNNNNGANNNNGGNGAYNNNGCNNNNCAYTTYGAYNNN MGNTTYAARCAYGGNAGYGAYACNAAYACNYTNGTNTGYACNCAYAARCARGGNGGNCAY TAYGGNGCNGARGARMGNCARGTNAGYCAYTTYCCNTTYCAYCCNGARMGNGGNTTYGAY ATHATGATGMGNGTNGGNCCNGARTGYATHGCNGTNGCNGTNAAYAAYCARCAYYTNYTN GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GAYCAYACNYTNGGNCARGTNACNMGNAAY ATHCARGAYTCNAAYMGNYTNATHGARACNATGACNGCNGTNGARAARYTNMGNYTNATH MGNMGNGAYGCNGCNGARAARMGNGGNGAYTCNGAYYTNGGNGARTCNMGNGARAAYGTN GARCARAARATHGCNGAYATGACNMGNYTNGTNAARTGYCARYTNGARGTNTAYAARGAR GARGARGCNMGNYTNAAR------------------------------------------ ------------------------------------------------------------ ---------------ATGGARAARGAYATHGAYGAYYTNYTNGAYGARGTNGARATHAAR TTYGTNCAYAARMGNAAYCCNMGNMGNTCNGTNAARAARACNGARYTNTCNAARAARMGN TCNAAR---------------ATHGAYGAYGCNATHAAYGAYATHYTNGAYYTNGAYATH AAYGAYGARGTNACNGARAARGGNACNGCNAAYACNTCNGTNGAYAAYACNGCNTCNAAY TGYTCNGGNACNCCNMGNTCNGARGCNACNAARAARTGYTTYCCNGTNTTYYTNGGNGGN AGYGCNGAYGARACNGGNMGNGGNACNACNATHAAYACNMGNGCNTGYAAYMGNYTNMGN TGYACNTCNTGYGAYTTYCARATHTGYTAYTTYGAYAAYTTYTCNTGGTCNAARGAYGCN AAYTAYYTNTTYYTNMGNAAYAAYGTNCCNGAYTTYCARAARYTNAARTCNAARYTNTCN MGNAARAARGGNTGYMGNGCNTAYTGYTGYCARTGYTCNTGGAARGAYGTNTGYTCNYTN TGYGARATGAAYGAYCCNAGYYTNAARTGGGTNTGYGGNAARCAY--------------- ------------------------------------------------------------ ---TCNTAYYTNACNGCNTCNGAYATHACNACNAAYGARGAYATHAARGGNACNTTYACN GCNMGNMGNGGNCARGAYAAYTTYAAYCCNTTYAGYAARGGNTCNYTNTTYTTYAAYTGY YTNGGNATHYTNTGYGGNCCNACNCCNCCNAGYYTNYTNGARMGNMGNAARYTNACNGTN CCNGARCCNGAYTCNATGCCNAAYAGYAAYAAYTCNGGNGTNACNCCNYTNCCNGAYMGN GTNGCNGTNGTNGTNTCNGARGARGTNACNACNGAYCCNGTNAARAARMGNGAYATGATH AGYTAYCARAGYCCNGAYGGNTCNATHAAYAAYAARGTNCCNTCNGCNAAY--------- ---------GGNCAYMGNGTNAAYATHTAYCCNTCNTCNCARGGNGGNGTNAAYTAYTAY MGNGAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CAYYTNYTNAARTGYMGNAARAAYTAYTGYGGN GTNGARYTNGCNGTNTGYCCNTAYAAYGCNATGCAYGARGTNAAYAARCCNGARYTNMGN TAYCAYATGATGCAYTGYACNGAYAARAARATGYTNGARMGNGARGTNGCNCAYAAYGCN ATGYTNCAYGTNTGGATHGGNAARGARCCNAAYYTNGARAARGGNTAYACNGAYATHCCN MGNCCNGCNAARGTNAAYTTYGCNCAYGARGARGAYYTNGARGAYTGGGAYAAYAAYGTN CARCARMGNMGNTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYMGNGCNAARYTNTTYGGN GCNYTNMGNGTNATHTCNAARGARACNAAYAAYTTYMGNAAYAARGTNMGNATHTGYACN GARATGTTYGTNCAYGAYGTNATGGAYTTYAGYATHYTNGARGARATGCCNTGGCCNYTN YTNGTNCARATGTCNAARGAYCARATHAAYCCNACNMGNGGNCCNTGGMGNGCNACNYTN CARCCNGCNAGYTAYCARTCNATGATGACNTAYTGYMGNGAYMGNYTNACNMGNTGGAAY YTNTGGCAYGCNTAYAAYAAYAARGCNTCNCARATGCAYGCNTCNCARTTYYTNAAYAAY AAYAARYTNATHGARAARYTNMGNACNTAYMGNGCNGAYGTNGCNAARATGYTNGGNTAY GARAAYTTYGTNGARATGTCNATGGARACNAARATGGCNGGNAAYGTNGARAAYGTNYTN AGYATGATHGARTCNYTNAARCARMGNTTYGCNCCNATHYTNTCNGARGAYATHGCNCAR YTNCARCARTTYGCNGARTCNGARGGNTTYAARAAYAARYTNGARATHTGGGAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGGAR AAYAAYAAYGCNATHGCNGCNCAR---GGNCCNGARGGNGARGCNGARATHGARAAYGTN AARCCNACNGCNGARGARGGNGARGARTCNCCNGGNAARGGNMGNGGNGGNTAYAAYMGN MGNMGNCARATHMGNMGNGAYGTNCAYCCNGARGAYGARACNGGNAARTGGTCNATHMGN MGNAARATHTGGGAYCAYYTNGARGAYAGYGAYYTNGTNAAYGCNCCNMGNCCNTGYCAY TAYMGNATHCCNAAYTTYGARGGNGCNGCNGCNGCNAAYGAYMGNYTNACNTCNYTNGAR GTNTTYCARAARGCNATHACNATHAARGTNAAYCCNGAYAARCCNCARGARCARGCNMGN TTYGTNATHYTNGAYGCNGAYAARGARYTNGTNYTNYTNAAYCARACNGARMGNACNYTN ATGGTNCCNACNCCNCARYTNAARACNGGNYTNYTNAAYMGNGTNGTNCCNYTNGARAAR TCNGAYAARGARCARYTNMGNCAYTGYTGYACNTCNCARGGNGTNAARGARAAYAGYAAR GARATHGAYATHGGNGAYAARATHAARYTNGAYYTNATHTTYGTNGGNAGYGTNGCNGTN TCNMGNGAYGGNTAYMGNATHGGNAARGGNAARGGNTAYGCNGAYYTNGARTAYGCNATG ATGMGNACNATGGARGCNGCNGAYGARAAYACNATHGTNATHACNTCNGTNCAYGAYTCN CARGTNGTNGAYATHCCNAARGARYTNGTNGARGARCAYGAYGTNACNGTNGAYTAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARCARATG GGNACNATHGCNTTYGAYMGNCCNACNGTNYTNMGNGARACNGTNCARTTYTTYYTNCAR TAYAARCAYTAYTGGAGYAGYCAYGAYTAYGAYMGNATHTCNAAYYTNGTNGTNGARYTN TTYCCNGARTTYAARGAYGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MGNMGNATGTCNTCNTCNMGNAAR GGNAARTCNACNATHGAYAARGARTGYTCNATGATGGAR---------AAYAGYGTNGAR CARTCNAAYYTNCCNTCNCCNMGNGTNYTNAAYAAYCAYGTNACNTTYGARYTNCARCCN MGNGAYATHCARMGNAARAARCCNAARGTNGTNTTYGTNTAYMGNAAYTTYAARGAYGTN GCNGTNTCNTTYTAYCAYCAYYTNMGNAARATHCCNGTNTTYGARTTY---AARGGNGAR TTYACNCCNTAYYTNGAYMGNGTNGTNTCNGGNYTNATHGARAGYGGNAGYCCNTTYGAR TAYGTNMGNAGYTGGGARMGNGGNATHCARTCNCAYCCNGAYYTNCCNATHTTYGTNTGY TCNTAYGARGAYATGAARGAR--------------------------------------- ------------------------------------------------------------ ------------AAYCCNYTNTCNTGGATHAARMGNYTNTCNCARTTYYTNGGNAARAAY CAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARGARGGNAARMGNGTN TGYCARGTNCCNACNGTNGCNTTYYTNCCNCAYTGYGGNAARGCNYTNTAYAAYAAYTTY ATHTGGGCNAAY---TGYGGNATHCAYAAYACNGTNYTNATHGGNAAYAGYTTYTCNMGN ATGYTNGARAGYGTNCCNCARMGNCARYTNGCNCARACNGCNAAYTAYGTNATGAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGCAYAARGARMGNCAYCARYTNGCNGARGARYTNMGNCAR GARCARGARCARYTNGAYAARGCNAARCARGARAARAARGGNGTNGARGGNGAYGTNGTN MGNYTNAARATGGCNMGNGARCARAAYAAYAARAARYTNACNGARATHMGNGGNMGNGTN GARGTNAARYTNAARGARTTYGARGGNYTNCARGAYMGNTTYTCNGARGARGTNGARGTN AARACNGCNTCNGCNYTNMGNATHGGNATGTCNGCNTTYAGYGGNGCNGCNTCN------ CCNTCNCCNAGYMGNGTNGCNYTNGAYGAYYTNCARGCNTCNCCNCCNGCNGCNCAYGGN GAYTTYGAYYTNAGYGAYGAYGARGARGAYYTNTAYYTNYTNGGNAAYAAR--------- ------AARTCNGAYTCNCCNTGGTAYAAYGCNYTNTGGAGYGGNGCNGAYGCNTCNMGN ACNTTYYTNTCNGGNGGNGARATGGGNGGNYTNMGNGARCAYYTNCARMGNGARGGNYTN ATGGTNGCNAARGCNAARACNTTYYTNCARAARCARMGNMGNAAYYTNMGNCARMGNCAR TCNGCNYTNGTNGCNGCNAAYGARGARYTNACNAARGAYACNMGNYTNYTNAARCARGGN AAYCCNACNMGNGARGCNACNGAYNNNYTNNNNNNNNNNNNNGARNNNYTNGARYTNGAR AAYCAYGARATHGAYGCNYTNCARTCNGARGTNGCNTCNGARTCNACNGCNYTNMGNCAR AARGARGARGARTTYMGNCARYTNGARGAYATGGCNGAYGARAARGARAGY---GAYGAR YTNGAYTAYAGYCCNTAYGGNMGNCCNTTYCAYMGNGTNMGNGTNCCNAAYATHGAYYTN AGYGARGAYGARAGYAGYGGNATHAGYAGYTCNGAYGCNAGYYTNGAYGGNATHYTNCAY GGN---CAYCARTAYTAYGGNMGNCCNGCNGARGAR---------CCNGGNGGNGGNGGN GAYGAYATHTCNMGNGCNYTNCAYAARATHAAYTCNGARYTNACNCAYGTNYTNAAYGTN ATHCAYAARGAYGGNGARYTNGARACNGCNCCN------CCNAARCCNCCNCCNACNCAR CAY---TCNGGNYTNCCNGARMGNGTNTCNTGGTCNCCNCAYCCNCCN---AGYCARCCN CCNAARGAYTAYTCNACNYTNGTNTAYACNGCNGAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TCNATG CCNTCNYTNMGNCCNMGNATHAARTGYGTNCARAARAAYCARGARGCNTTYYTNCCNCAY GGNGCNYTNYTNGCNTTYCCNMGNGAYCAYYTNACNTAYYTNAAYGARGTNGGNTCNAGY TGGTTYGGNCARGCNATHGAYTCNGARGCNTTYMGNATHGGNGGNGTNAGYYTNAARAGY MGNGTNGTNGTNAARATHYTNAARGAYGARGCNTCNAARAGYGARCARAARCARTTYATG GAYGARATHGTNGCNTTYMGNAAYGTNAARCAYGARAAYGTNATGAGYGTNATGGGNYTN TGYACNGARACNTCNCCNTAYYTNGTNATHYTNGARCAYGCNCCNAAYGGNAAYYTNAAR GAYTTYTTYCAYATHCAYAARCAYAGYATGGARGTNYTNATHAARAARAAYAARYTNYTN CARTTYAGYYTNAAYGCNGCNTCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MGN CCNTTYCARCCNMGNTGYCAYCARYTNGGNCARACNGAYGGNAAYATHCCNAGYGGNGAR GCNTGYATHMGNCARTTYYTNTAYGGNCARAARTTYTTYATGCARGARTTYGGNATHMGN TGYAARGARTTYTGGYTNCCNGAYACNTTYGGNTAYTCNGGNCARTTYCCNCARATHYTN MGNCAYTGYGARGTNAAYMGNTTYYTNACNCARAARYTNAGYTGGAGYYTNGTNAAYAAR TTYCCNAAYCAYACNTTYTGGTGGGARGGNATHGAYGGNTCNTCNGTNYTNACNCAYTTY CCNCCNGGNGAYTCNTAYGARATGACNGGNMGNGCNAGYGARYTNATHAARACNGTNMGN AAYTTYMGNGAYAARGGNMGNTCNAAYMGNTCNGCNTTYYTNTTYGGNCAYGGNGAYGGN GGNCAYGGNCCNAGYGARGARATGYTNGARMGNYTNAARMGNTTYCARGAYTGYGAYGGN YTNCCNAARGTNAARYTNACNGGNAGYGAYGARTTYTTYTCNTCNATHGARAGYGARGAY ACNAAYATGYTNTGYMGNTGGMGNGGNGARYTNTAYYTNGARATHCAYAAYGGNACNTAY ACNACNTGGGCNAARGTNAARAARGGNAAYMGNGARTGYGARATHYTNYTNGTNGAYYTN GARACNYTNTGYAGYATHGCNTGYTTYCARGCNCARGARTGGATHTAYCCNTAYGARGAR ATHGARMGNYTNTGGAARYTNYTNYTNYTNAAYCARTTYCAYGAYGTNYTNCCNGGNACN TCNATHTCNGCNGTNTTYACNGAYGCNATGAARAAYTAYCARGAYATHCARGGNTCNTCN GCNAARYTNYTNAAYGARGCNGTNGCNGCNATHGTNAGYAARGGNGCNGTNCCNTCNGAR AARTCNTCNCCNTGYGTNCAYGTNGTNAAYACNCARGCNTTYGARMGNCARGARGTNATH GARAGYMGNYTNGTNGCNGAYYTNTAYAARCCNGCNACNAARMGNMGNTGYYTNGARGAR TCNACNGAYGARGTNMGNGTNCCNCCNATGTCNGTNGTNCCNYTNTGYGAYTGYGTNGTN TCNCCNGTNGARYTNMGNMGNGAR---GAYAAYTTYGTNYTNAGYAAYAGYYTNATHAAR GCNGTNYTNGAYCCNATHGGNMGNYTNYTNTCNYTNACNTGYTTYGAYACNAARACNCAR AARTGGAGYAARGARGCNATHAGYCARGARCAYCCNGCNAAYCARTTYYTNYTNTAYGAY GAYATGCCNYTNTAYTGGGAYGCNTGGGAYGTNATGGAYTAYCAYYTNGARACNMGNAAR ACNGTNATHCARMGNGTNATGGTNCAYGAYAAYTCNAGYTCNYTNMGNGTNGCNYTNGAR GTNAGYYTNAARATHAGYAAYCARAGYTAYYTNAARCARGARATHGTNYTNGAYGCNGAR TGYCCNTAYGTNMGNTTYAAYACNGARGTNACNTGGGGNGARAAYMGNAARTTYYTNAAR GTNGARTTYCCNACNACNGTNCAYTCNATGGARGCNACNTAYGAYATHCARAGYGGNTTY YTNMGNMGNGCNAAYCAYTTYAAYACNTCNTGGGAYTCNGCNMGNTAYGARGTNTGYGGN CAYAARTGGGCNGAYATHTCNGARCAYGGNTTYGGNGTNAGYATHATHAAYAAYTGYAAR TAYGGNTAYTCNGCNGTNGAYGGNATHATHMGNYTNTCNYTNYTNAARTCNCCNAARAAY CCNGAYCCNAARGCNGAYATGGGNGTNCAYAGYTTYTCNTAYGCNGTNTTYCCNCAYACN GGNAGYTTYCARGARGCNGGNYTNATHCARCARGCNYTNGCNTTYAAYTGYCCNYTNMGN ACNGTNYTNYTNCCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GGNAGYTAYYTNTCNGCNGGN AGYAARATGAAYGCNGARGGNMGNYTNCAYYTNYTNCCNCARGAYCARTGYGGNAARGAY GAYAGYAARGGNTTYGCNMGNYTNCCNCARGAYTGGGTNGGNGTNATHCAYTAYACNGCN GARACNGAYGGNAAYTTYATHGARGAYGGNGTNYTNAAYTGYCCNYTNGTNYTNGAYMGN GTNMGNAARGCNYTNATGTTYGGNGCNTCNGCNATHATHATH------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TGYAGYATHCARTCNGGNGAYGAYATGTAYGTNGCNAARCCNGTNTTYACNTTYCARGAY YTNMGNAARGCNACNCARAAYTTYAGYGARAGYACNATHYTNGGNMGNGGNGCNTTYGGN ATHGTNTAYMGNGGNACNATHMGNAAYAAYGAYTGYGCNGTNAARMGNYTNATHGARATG CCNACNGARCAYGGNGAYAARATGGARMGNATHAARACNGARYTNACNGCNYTNNNNNNN TTYCARCAYGTNAAYATHGTNMGNYTNTAYGGNTAYGCNATHGAYGGNCCNGARATHTGY ATGGTNTAYGARTAYYTNAARAAYGGNTCNYTNGAYGAYMGNYTNAARYTNAARAAYAAY ACNCCNGTNYTNCCNTGGGARMGNMGNGTNAAYATHYTNGTNGGNGCNTGYCARGGNYTN CAYTTYYTNCAYACNATGGGNATHCARCCNYTNATHCAYGGNGAYATHAARAGYGCNAAY ATHYTNYTNGAYMGNTAYYTNGARGCNAARATHTGYGAYYTNGGNCARGCNMGNTAYGCN GCNAGYMGNAGYTGYGAYAGYACNGGNATGACNCAYATHACNYTNGARGARTCNCARTCN AARYTNTAYTGYACNAARGCNTTYCARGCNCCNGARATH------TCNAAYAAYAGYAGY YTNTCNTTYAARTCNGAYGTNTAYGCNATGGGNGTNGTNGTNYTNGARGTNTGYACNGGN AARGCNGCNTAYGAYTTYAAYMGNAAYGARAAYAARTTYYTNGTNAAYYTNTTYAAYYTN CAYTTYAARACNMGNAGYGGNGAR---GARTGGGTNGARGARYTNATGGARMGNMGN--- GCNAAYCAYATHGARCCNAGYGTNTTYATHAGYATHATGAARATHGCNAGYAARTGYGTN GARAAYGTNAARAARGCNMGNCCNACNAGYGARAARYTNYTNTCNCARATHAARACNATH TAY---------------ACNATHGAYGGN------AARAARYTNAARATHTCNCARGAY AAYGTNTCNYTNGAYATHGGNAARGAYAARCCNATHTCNGGNACNACNACNATHGCNAAR CAYYTNYTNMGNACNTCNAAYGARTCNAARGGNYTNACNYTNGARGAYMGNATGYTNGCN GARCARTGGYTNGARTAY------------GGNGCN------------MGNCAYGCNACN GGNGAYMGNGARMGNYTNCARGCNGTNYTNCARGAYYTNAAYGTNTAYYTNAARGAYAAR GTNTAYTTYGTNGCNGCNMGNYTNACNATHGCNGAYATHYTNYTNTTYCAYAGYGTNTAY CCNYTNTTYGARAARATGACNTTYCAYGARAARGARAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GAYGCNGTNCARGGN GGNGTNAAYGAYTGGYTNATHTCNGCNTTYGAYTTYGARAARGAYTCNYTNGCNCCNGTN GARTTYAGYCARGAR---TCNGTNGCNAAYACNCAYGCNYTNGAYATHGAYYTNGARCCN TCNMGNYTNAARGAYYTNATGAGYAGY---YTNGTNTCNTGYYTNCCNGGNGAYTCNMGN YTNAARGCNAAYAARGCNGCNTTYTGYACNCAYATHATHMGNAARGGNTCNAGYGARYTN TGGMGNYTNMGNGTNGARTGYAAYCARTCNGARYTNACNACNYTNYTNAARGGNYTNGTN TCNCAYGAYTGYAARGARAGYTAYTCNGTNTCNCCNYTNTCNAARGCNCCNAARYTNAAY ACNGGNATGGGNMGNAARGCNACNYTNAARAARCCNCARTCNYTNGARGARYTNGTNGAY CARGTNMGNACNCAYYTNGCNYTNAARCAYGTNGCNGTNGCNAARCCNATHGGNGARGAR GTNMGNGARATHCAYTCNGTNGCNGTNTGYGCNGGNTCNGGNTCNAGYATHYTNAARGGN GTNMGNGCNGAYYTNYTNGTNTCNGGNGARATGTCNCAYCAYGARGTNYTNGAYGCNGTN CAYGARGGNAGYGCNGTNGTNYTNTGYCAYCAYTCNAAYACNGARMGNGGNTAYYTNAAR GTNYTNCARGGNAARATHMGNAARGCNYTNGGNTCNGCNGTNGARGTNTTYGTNTCNGAR ACNGAYAARGAYCCNYTNGARATHGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GCNGGNCCNTCNCARTCNCAYMGNAAYYTNGTNGCNATHYTNAAYCAYAGY ATHCAYAARCARACNACNTCNACNGAYACNCCNCCNATHCCNGARYTNYTNMGNGAYATH ATGAAYYTNGARCCNYTNYTNAGYGAYGAYGAYATHCCNGCNGAYTCNATHATGGARAGY CCNTTYCARGAYCARGAYYTNTAYACN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYACNGARCCNTAYGAYTCNAARATHMGNAGY YTNYTNYTNAARGTNGTNCCNYTNCARTCNGGNGAYTGYYTNGGNTGYAARYTNGTNGGN ACNTCNGTNATGTTYGCNAGYGGNATHATHGTNYTNACNTCNGCNGCNGTNGGNAARGCN MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARAARAARCCNCCNTCNACNYTNCARGARTTYYTNACN GCNGARGGNYTNGARGAYTGGCCNYTNCCNATGAGYYTNGARMGNCCNYTNGAYATHGAR GCNGARGGNYTNTTYATHGGNACNCARGARGAYATHGCNGAYATHYTNAAYGARGCNGCN CCNYTNGGNYTNCAYATGATGGGNGARATGGARGAYMGNYTNGCNTCNYTNGAYGGNAAR ATHAAYCAYTAYGCNAAYCARATHGTNACNAAYGAYAARMGNCCNTCNMGNYTNTCNGAR MGNYTNTTYCAYTCNCCNACNMGNACNTTYATGACNGARATGTCNGARTCNGAYGCNMGN AARTCNCAYMGNAGYTCNMGNGAYCCNMGNAGYGTNGAYYTNATGGAYGCNATGYTNGAR ACNMGNAARAARAGYYTNGAYTAYTAYACNTTYCCNGGNTTYGTNCAYGGNGARTTYATH GARYTNCCNGCNCARYTNGARGCNCCNCCNATHYTNCAYMGNATHACNAAYGCNCARGAY TTYAAYCCNGGNTTYAARAARTTYTGGAARAARYTNTTYYTNTCNGARGCNTCNTCNGCN GTNATGCARGAYACNTTYTGGTGGATHTTYYTNGAYATGTTYAAYAARATGGARGGNTTY AARGARGAYAARGAYTGYYTNTTYGAYMGNATHGCNGAYAGYTAYGTNGCNYTNTTYACN AGYATHAAYACNGAYGTNAARGAYAARTTYYTNTCNGTNTAYCCNGAYTGYYTNTCNCAR GCNGTNTTYTGYGCNTAYMGNGARGCNTTYCCNGARTCNCARTGGTGYTTYGAYGARCAR TTYAARCARTAYYTNGTNAAYCAYGTNTAYGARTGGGTNACNGGNYTNMGNCCNGTNCCN GGNGTNTGGAARGCNTGGAARGARGARAGYYTNGARGGNGCNCARACNAAYMGNGAYAAY GARACNGCNAARAARATGYTNGARGCNGCNGCNYTNAAYAARAARGTNGARYTNATHYTN GAYATGGAYTCNTTYGCNAARGTNATHGAYAARYTNGGNACNGTNGTNTCNGCNACNCCN CARGGNATHGTNTCNMGNGARATHACNAARACNTCNAAYTCN------YTN------CCN TCNCARGGNAARTCNCAYYTNGCNAARGTNGARTCNCAYCARATHGGNCCNGGNCCNGAY TAYGARMGNGTNAARTTYAAYACNTCNGGNMGNAGYCCNYTNATHGCNCAYTAYYTNCAY ATGMGNCARYTNMGNAGYTAYAARCARCCNGGNACNMGNGTNMGNMGNACNGARATHYTN AARYTNCCNCCNGTNGGNCCNACNTAYMGNCARTTYATHTCNACNACNYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARCCNGGNCARCCNAARYTNGAYMGNGAYTAYTTYATHYTN CCNCAYCCNGCNYTNATGGCNATHATHTCNTTYTTYYTNTGGTAYYTNGTNAAYACNACN ATHGCNCCNGAYACNATHCCNGAYGCNTTYGGNCCNTTYGCNACNTTYGGNAARTTYYTN GGNAAYTCNTAYCCNTCNGTNTGYATHTCNYTNAGYTAYGGNTGYYTNGCNATHCAYATH YTNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------ACNACNGGNCARGTNYTNYTNTTYYTNGAYAGYCAYTGYGAR GTNACNAAYGGNTGGYTNGARCCNYTNYTNAAYGTNGTNCAYTCNAARCCNCAYACNGTN GCNGTNCCNYTNATGGAYATHATHAAYGCNGAYACNTTYYTNTAYGARACNTCNTCNYTN GTNAARGGNGGNTTYAAYTGGGGNATGCAYTAYCARTGGGAYCARYTNAGYAARGARGAR GCNGCNAARATHAGYGAYTCNCCNGARCCNTAYMGNTCNCCNACNATGGCNGGNGGNYTN TTYGCNATGGAYMGNTCNTAYTTYTAYGARYTNGGNGARTAYGAYAARGGNATGGAYATH TGGGGNGGNGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TGYTAYMGNCARAARMGNGTNAAYAAYAAYAARCAR MGNTGYCCNYTNMGNTCNMGNGARGCNGARAARAAYMGNCCNYTNGGNAAYGTNCARACN CCNCCNCCNMGNAGYTCNGCNGCNAAYGAYTCNGTNGGNYTNTGYTCNAAYGTNGAYACN ACNAARGAYAGYGARACNTTYTTYCCNATHAARCCNTCNGARCCNGARCARAGYACNGGN TCNAARGAYGARATHGTNAARYTNCARYTNGARATHGARGGNTGYYTNCARTTYYTNCAR CARATHGGNGARMGNGTNYTNCARGGNGGNAGYACNGARTTYYTNCARTCNCAYCCNMGN GTNAARYTNAARGAYGGNTAYYTNACNGARATHGARGAYTAYGAYMGNGCNMGNYTNMGN GCNGGNGARCARAAYACNMGNTCNACNMGNAAYYTNTAYAAYYTNMGNCARAARGTNAAR CARYTNCARMGNGAYATHACNMGNGCNGARYTNAAYAARCCNGCNMGNAARAAYCARATH AARAGYCARYTNGTNACNACNTAYMGNGGNGCNATHMGNGCNYTNCARACNTTYGTNAGY CARYTNCCNTAYCARGAYYTNTCNGCNGGNYTNCCNGCNAGYTAYAGYGARYTNGCNYTN YTNYTNMGNCARYTNACNGCNYTNACNGAYYTNACNCARGCNGGNMGNCAR--------- ---ACNMGNYTNYTNGCNYTNYTNGAYCARGTNGAYAGYGTNAAYTCNAARTGGTGYATH CARTTYYTNMGNAGYGAYTTYYTNGCNGTNCAYMGNGARAARAARATGGCNATHTCNAAR GARTGGGTNAGYGAYACNAARGTNGAYGCNGAYATH---TTYTCNAARATGGARGCNATH CAY---CCNCAYTCNYTNAARGCNGCNGCNACNCARCAR------CARMGNGGNMGNCCN GTNAARCARACNATHGGNAARGARAAYMGNGGNAAYGCNCARAARGARMGNAARGCNGCN YTNGARACNGGNGTNGCNGCNYTNGCNGGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TTYGAY GAYGAYGAYGAYGAYAGYYTNTAYGGNGAYCAYYTNTCNAAYAGYTGYTTYGCNTCNYTN MGNATGGAYMGNMGNGAYAGYGAYGAYTTYGAYGAYGAYYTNMGNTCNYTNGARTGGYTN CARAGYGARGAYYTNYTNAARAAYATHGGNGGNGAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MGNMGNGAYCARATH GCNGARGGNTGYGTNAAYAARGTNATGGAYTTYTAYTTYATHYTNGAYTCNTCNTCNTCN ATHTAYACNAAYGAYNNNNNNNNNNNNNNNNNNNNNNNNMGNNNNGTNNNNNNNNNNTTY GAYGTNNNNCCNGARAARACNMGNGTNGGNGCNYTNACNTTYAGYGAYGAYTAYCARMGN CCNCCNYTNGGNYTNYTNMGNTCNCARACNAARAGYGAYATHYTNGCNAGYATHAAYGCN CARAAYYTNCCNTAYMGNACNGGNGTNACNAAYACNGAYCARGCNATHMGNTAYGTNMGN GARAAYAAYGARTTYMGNGARGAYATHACNAARGTNATGGTNGTNGTNACNGAYGGNGGN TCNMGNTCNCCNGGNGCNACNGCNGCNGARGCNGCNYTNGCNMGNGARCARGGNTTYTAY ATGTTYGTNGTNGGNATHGGNCARTAYYTNGARGARMGNGARTGGMGNGCNATHGCNAGY GAYCCNGAYGARAAYTTYYTNTTYAAYATHACNAAYTTYCARTTYYTNGAYAGYGTNAAR TAYAGYYTNCCNCARMGNGCNTGYTCNYTNCCNCCNATHATHGTNGGNGGNTCNTGYTAY GTNGAYCARTTYTCNGARGTNTAYTTYGTNGCNTCNAGYAGYGCNAGYGAYGARGCNATH CARYTNATHGARAAYTTYAARGCNMGNACNMGNGAYGAYGGNCARYTNGTNAGYYTNAAY TAYATGATHGARAARTGYAAYTAYGCNACNGGNGCNCAYGTNGGNGAYGARYTNGAY--- ---TGYGAYMGNGAYGTNCCNATGACNGARAAYACNGCNGGNGCNAAYGAYGCNYTNYTN TCNMGNGCNMGNAAYGTNGCNMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TTYAGYTGGYTNAGYAARCAYGGNCCNCARTTYCAY ATHCAYGGNGAYCARGTNCARGTNATHTCNGARCCNACNCARTTYTAYGARATHYTNAAR YTNAARACNMGNAARGCNAARGARMGNGTNACNYTNGCNTCNYTNTAYYTNGGNAAYGGN CAYYTNGARGARGAYYTNGTNTCNTGYATHAARGARGCNTGYCARGARGCNCAYAGYCAY GGNYTNGARAAYTTYGARGTNAGYATHYTNYTNGAYTCNACNMGNGGNTCNMGNGGNAGY AARAAYTCNMGNACNATGYTNTGYCCNYTNATGAARGARTTYTCNAAYGTNCAYGTNGCN YTNTAYCAYACNCCNGAYYTNMGNGARTTYYTNAARAGYATHGTNCCNGARMGNTTYAAY GARACNATHGGNYTNACNCAYGTNAARATHTAYYTNTTYGAYGAYAGYTTYATHATHAGY GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TCNNNNNNNAARGARYTNGARGGNCARYTNACNATHGCNGARAAYMGNTGYCARYTNYTN GGNAARCARYTNGAYTAYATGMGNAAYYTNGTNGAYAAYTCNGARMGNGAYMGNMGNYTN ATHGTNGARAARACNYTNAARGCNMGNCARGGNAAYGAYGGNGGNGCNGAYYTNAARYTN CAYYTNGAYMGNYTNAAYGARYTNGARMGNGAYCARYTNMGNYTNACNGCNACNCARAAY YTNGCNGARATGAGYTAYAARCCNGCNACNCCNGTNGTNAARGCNMGNMGNCCNTCNAAR AARMGNAARAARAARAAYCCNCCNCCNCAYYTNCARMGNCCNGCNCAYACNTGYAARTCN GARCCNATGMGNCAYTAYMGNYTNAAYYTNGCNGARATHCCNTTYGTNGCNGGNAARTCN ACNGCNCCNAGYCAYGCNYTNGGNGCNAAYGTNCARAARGTNYTNGCNATGATGAARTCN CAYAAYACNGCNYTNTGYTCNCARATGTAYGCNAAYGGN------GAYGGNCAYMGNTCN ACNAGYCCNGCNTCNTCN------GGNTCNATHACNTCNAGYGCN---GAYCCNGAYYTN ACNGAYYTNYTNAAYCARYTNCARGTNGARTTYGGNCARYTNAGYAGY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MGNTCNTAYCCNGGNCARMGNCCNGAYAGYMGNGARACNTAYAGYGARGGNGAY TCNMGNMGNCCNGARGTNCARACNTCNCARTCNGARATHATGMGNGGNAAYGAYGCNGGN GCNCARMGNCCNYTNACNGAYTCNAAYTAYGTNMGNAARAAYYTNGTNGAYGGNGGNTCN GCNATGYTNTTYTCNGCNTTYCAYMGNGAYAGYATHAGYAGYTCNCCNCARATGATGACN TCNACNCCNTCNTCNTCNCARGCNGGNGGNTCNATGACNGCNGAYAARYTNATHAAYGCN ATHATHATHCAYTCNATHAAYCARACNTCNCCNGARGARAAR---AGYYTNTCNGCNTCN CCNATHMGNCARTCNMGNCCNACNTCNGGNGAYCCNGCNGTNAGYTCNCARGGNGAYCAY MGNCCNACNTCNGARTCNGTNTCNTAYATGGGNGAYGCN---GTNGGNMGNTCNGAYACN GTNGAYCCNMGNCARMGNGAYYTNATGGAYCCNMGNYTNMGNYTNCARCAYGCNGCNGAR MGNCARMGNCARGAYATGGARCARGGNMGNMGNCARGARCAYMGNCARMGNCARGARYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYATH YTNCAYAARGAYGCNCARTGGGARTCNGTNGCNATHGCNTAYAARGARMGNGARCARGCN GCNTCNMGNGCNTTYGARYTNACNTCNGARGCNMGNMGNTCNGTNGARAARYTNAARACN GTNYTNGARGARGGNAARATHAAYAARGTNACNAARAARAAYACNGCNATHTTYCCNGCN ACNAARAARYTNAAYGARATGACNAARGARATGTCNCAYGCNGCNTCNCARATHMGNCAR GCNGAYGCNGARGCNAARGTNATGYTNAARTAYAARGAYYTNGTNGAYAARGGNMGNMGN CARTTYCARATGGARYTNGARAGYYTNYTNCCNGAYGTNAARYTNGGNAAYAARAGYMGN AARYTNACNGARGAYGARYTNAAYGCNYTNATHGCNCAYGCNCAYMGNMGNATHGARCAR YTNCARAARCARATHGCNGARCARYTNGCNATGGARMGNCARMGNYTNGCNATHTCNYTN GAYGCNCARMGNGAYGARGAYAARGGNATHACNGARGCNGCNYTNGARGAYGARMGNAGY MGNYTNAAYACNAARTTYGARYTNGAYAARCARAARATGGARATGGARTTYYTNGTNTAY CARGARGARGARGTNMGNAARCARYTNGGNMGNCARGCNGGNGCNCAYAGYGAYCAYYTN AARGAYGTNYTNTCNATH------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AAYGCNACNYTNCCN TCNYTNGGNTCNGAYATHGGNAAYGARTTYGTNAGYGARCCNATHACN---------AAY GTNAGYTGYGTNAAYCARGARAGYCCN------ATHAAYTCNTCNATGGAYTGGAAYYTN GGNGAYYTNGAYTTYYTNGGNGAYATHGAYATHYTNCARGGNCARCCNATHGTNGAYYTN GAYYTNCARAGYGTNGARGAYYTNYTNAAYATHCCNGCNCCNGTNGAYATGATHAAYACN ACNTCNYTNGAYTGYCARCCNGCNGGNTTYGAYGCNATHGCNGCNTTYACNGARGARYTN GARCCNACNACNATGTAYGAY---------------------GTNACNAAYGCNAAYGTN CCNCCNGTNGAYGTNTTYAGYGAYGAYYTNGGNGGNYTNGARGGNGCNATHGGNGGNACN GARTTYGAYCCNAGYGAYMGN------------------GGNAARATHTCNMGNYTNTCN GAYTCNTCNAGYGAYTCNGGNTTYGTNTAYCARGGNGGNTTYTCNAGYCCNTCNTCN--- ---TCNTCNTCNTCNTCNTAYGCNGCNAGYCCNGCNAGYTCNCAYAAYGGNAAYGGNTCN ACNTCNTCNAAYGAYACNGAYCAYGAYCCNCAYAAYACNMGNACNYTNGCNCAYCARGTN GCNCAYAAYCAYACNTAYAAYACNYTNCCNGGNCAYYTNCCNMGNGARGTNAARAARTAY GCNCARAARGAYCCNTGYMGNAARGGNCCNCAYAGYMGNGAYCARAARMGNGCNGARGAR ATGAARATHCCNTTYACNATHGAYGARATHATHGARTCNCCNGTNGARACNTTYAGYGAR ATGYTNTCNAARTAYAARYTNAGYGARGGNCARYTNAGYATGATHMGNGAYATHMGNMGN MGNGGNAARAAYAARGTNGCNGCNCARAAYTGYMGNAARMGNAARGTNGGNGTNATHGTN ACNYTNGCNGAYGARATGYTNGARYTNGARAARGCNMGNGAYMGNYTNAARGCNGARMGN GCNGARATGGARMGNGARACNMGNAGYCARMGNGARAARTTYGGNCAYYTNTAYTCNCAY ATHTTYCARTCNYTNMGNGAYGARCAYGGNCARCCNTAYGAYCCNAAYTTYTAYTCNYTN CARCARTCNAGYGAYGGNAAYATHTTYYTNGTNCCNMGNAAYGTNTCNAGYAAYGGNAAY AGYACN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CARATHAAYGARTTYTCNAARGAYTAYMGNGTNGTNGCNATHGAYYTNMGNGGNTAY GGNGAYTCNGAYAARCCNAGYGGNATHTCNAAYTAYMGNYTNGARCAYYTNGTNAARGAY GTNAARCARATHATHACNGCNYTNGGNTAYAGYTCNTGYGTNYTNGTNGGNCAYGAYTGG GGNGGNGCNATHAGYTGGGCNTTYGCNGGNTGYTAYCCNGAYYTNGTNGAYAARGTNATH ATHATGAAYTGYCCNAAYGTNCARGGNTTYMGNAARTAYATHMGNAGYCAYTGGGCNCAR TTYAARAARTCNTGGTAYATGTTYTTYTTYGTNATHCCNTTYYTNCCNGARTTYTAYATH ACNYTNAGYGAYYTNAARTTYTTYGAYATHATHTTYYTNGGNAAR---GGNGGNGTNCAY ACNGARTCNACNACNAARGARGAYGTNGARGTNTAYAARTAYYTNTTYCARGARMGNAGY TCNYTNTCNGGNCCNATHAAYTTYATHMGNGCNGGNYTNATGTTYGGNACNGCNTCNMGN YTNTCNCARAARGTNACNAARCCNGTNYTNYTNATHTGGGGNTGYCARGAYYTNGCNYTN GARACNGGNYTNGCNGARTGYTGYAARGARTAYGCNTAYAAYATGAARATHCAYTAYATH AARGARGCNAGYCAYTGGGTNCARATGGAYTAYCCNGARGAYGTNAAYGCNCARATGMGN GARTTYYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGYTNAAYAARGTNATHCCNTTY YTNMGNATHGCNCCNMGNGTNCARCCNATHMGNMGNATGGCNGGNGGNTAYGGNGTNCCN GGNCAYTGGAARTCNATHMGNCARATHTGYGARGARAAYAARAGYCAYATGAAYTTYATG CCNGTNCCNGARGGNTCNTGGCARGCNCAYCAYAAYGCNAARAAYTCNAARYTNAAYYTN YTNYTNGCNTCNTCNGTNGTNGCNGTNACNGTNACNTTYGCNACNYTNTGGCARTCNGGN TGYATHTAYTTYCAYGGNCCNCCNCCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GAYATGCARMGNCARATGCCNACNACNTCNTAYAGYCCNTTYGGNYTNACN AGYAGYCCNTTYTAYAGYACNGARATHGGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATHTAYGARAGYGAYAAY YTNTTYCARCARGARTGGYTNACNGGNAARACNCARYTNCAYCARGGNGAYCCNGAYAAR ATHACNATGGAYTCNAAYAAYAARTAYCARAARCARATHCARMGNGARATGCCNCARCAR CCNAARAARTGGTAYCAYYTNGAYGCNGAYGGNAARGARGGNCARCAR---AAYGARGAY ATHTCNATGCCNCARAARGGNCAYAARMGNTGGGTNGGNYTNCCNGARCCNGTNGAYGAY ACNGCNGGNACNATGACNACNGTNCAYCCNGGNTAYGAYCCNATHTTYATGCARTCNGAR AAYCCNAARCARAARTGGAARGTNAARCARAAYAAYGTNYTNAGYACNATHGTNCAYGAY TGGMGNAAYAARTGGTTYYTNAGYGGNCARTTYGCNGAYAGYACNCCNGARGAYYTNATH MGNGAYATGGCNGAYATHCARCCNCAYGTNMGNYTNAARGCNATHGGNACNGTNGCNAAR GCNGCNGARTAYAARCCNCCNYTNGAYAGYAGYATHATHYTNGAYAARTCNGTNACNGAR TCNGTNTCNCARYTNCCNGARCARATHTTYGTNGCNYTNGARTGYYTNYTNGAYGAYAGY AAYCARCARGTNCARACNGCNGCNGCNATHACNYTNTAYACNYTNGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGMGNCARGARAGYTGYMGNAGYTTYGARTAYGTNGARGCN GAYCARYTNGAYCARGCNAAYGTNGTNGARGTNYTNACNTCNGTNACNAARAAYTCNAGY CCNTTYAARGCNGGNAGYGARACNTGGGCNTGYGCNTGGGCNCCNGAYAAYTCNGTNTTY GCNTGGTCNTGYGGNCAYMGNATHYTNCAYYTNGTNCCNTGGGAYAGYAARAAYCARAAR AARCAYGAYCCNACNGAYGARAARGGNYTNAAYGGNMGNAARTAYCAYYTNATHGAYTGY TCNGARATHATH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYCAYYTNAARAAYACNTAYAAYGGNGAYGTNYTNGAYAARMGN GCNCAYTAYTTYACNGARCCNGARMGNCCNTTYACNCCNMGNACNYTNAARACNAAYCAY CARTCNMGNYTNAARAAYTCNAARTGYTAYAAYGCNCCNAARMGNACNAGYGTN------ AARCARAAYGGNGCNGAYCCNTCNYTNTCNCARTCNTAYATHAARGAYGARAARGARGGN MGNAARTCNCARCCNMGNCARATHAARGARACNYTNCCNACNAGYCARYTNTCNGARTCN ATHYTNATHGAYATGACNYTNCARAGYMGNAAYGGNCAYCAYGCNGARAAYGARAARMGN GARATHCCNCCNYTNGCNATHGCNATGGAYGTNGAYCAYYTNAAYTGGYTNCARGARCAR GCNTCNAARGCNCARGTNMGNGCNMGNCAYAGYAGYMGNTTYAARAARAAYCAYAARCCN AGYGGNGAYAGYCARGARAARGAYGAYCARACNGAYCCNACNAGYYTNAAYTCNGTNMGN CARGARACNGTNAARAARGARGARGARCARAARTAYYTNGCNTTYGCNAARGARGTNACN GAYGAYGTNYTNGCNAGYGGNATHTCNACNGAYMGNGTNYTNGAYMGNGTNTTYGARAGY CAYATHGARMGNMGNAARGARGAYYTNGAYGARGARMGNATGMGNGTNGTNGTNMGNGAY YTNAARAARGAYYTNGGNYTNGCNGARCAYTCNATGGAYMGNATHGGNGAYTCNACNYTN AAYGARGARAARAARGARGGNGGNGTNAARAARTTYCCNTTYTCNAAYAAYTCNAAYAGY AAYYTNAGYGCNACNYTNGAYTCNACNTCNACNATGAARTTYGGNCARACNGGNGAYATG TTYAGYACNATHCARTCNCARGARCARGARYTNGCNACNMGNACNGARATHGARAARGAY GAYGARAAYGGNYTNACNGAYACNCARGTNYTNAARCARTAYCARATGAAYYTNACNGCN AARGARGCNCARGGNGARACNAAYGGNAGYGCNGGNCCNACNGGNGARGARMGNGARTCN AAYTCNAGYGAYMGNCCNGCNACNGGNGARCARMGN------GTNMGN---CCNGCNAAY TCN---------------------------GAR---GAYTGYGARGARATHATGMGNYTN ATHTTYGARYTNGCNGARTTYGARAARATGGCNGAYCARGTNAARATHAAYGCNGAYGTN YTNMGNAARGAYTGYTTYTGYGARGTNCCNAARTGYCAYTGYATHGTNGCNGARCCNGTN GAYAGYGARTCNAARGGNYTNGTNGGNTAYGCNYTNTAYTAYCCNACNTAYTCNACNTGG GARGGNGTNGCNATGTAYYTNGARGAYATHTAYGTNACNTCNTCNYTNCARGGNAARGGN ATHGGNAARMGNATGTGGCARTAYGTNATHAARGTNGCNYTNGAYATGAAYTGYAGYMGN YTNCARYTNTCNGTNYTNGCNTGGAAYAARGTNGCNAARGAYTGGTAYATHMGNGCNGGN TGYGTNAAYYTNACNGARAARGARGARTGGTGYYTNATGMGNYTNACNMGNGAYGCNATG GARAARTTYGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GGNGGNGGNGARGGNGGNMGNTCN TTYGGNTCNGTNCAYTCNMGNGTNGCNAGYTAYCARTCNCCNMGNCCNTTYGTNTCN--- ---TCNTCNTCNCARTCNCCNGCNATGATHCARCARCARAAYGARAAYATHGCNCARYTN GARAARATGYTNGARAARGARMGNGAYGAYAAYAARAARYTNCARCARCARYTNGARGAY AARGAYAARAARATHGCNGARYTNGARAARGCNATGGARYTNYTNAAYAAYGARTGYGAY GGNYTNGAYGARGAYAAYATGAARYTNCARGARGARAAYAARGCNYTNATHMGNGCNATG TCNMGNYTNACNTCNAAY---------CAYGGNATGACNATHTAYCARGAYTCNGGNGTN GAYYTNGAYAGYCARGGNGTNGTNTGYAGYMGNTCNGTNCARACNGAYGAYAGYYTNYTN GAYGCNYTNYTNGARGARTAYGAYCAYGAYAARGTNAAYGAYTCNACNGAYAGYGGNCAY YTNTCNGGNTGYTTYGAYCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CAYGARATGGGNATHGGNAGYGTN ACNAGYYTNCAYAGYTTYTAYCARCARMGNGTNYTNGCNTAYCAYGCNMGNATGAARCAR CARTGYGARGCNTGYGTNAAYGARTAYAAYTCNYTNGTNAARCARCCNCARACNGCNTCN TCNGGNAARCARACNTCNTCNTCNGGNTCNGGNGAYACNYTNCAYGTNATHMGNATHAAR GARGARCCNAGYACNGARATHCARTTYCCNYTNYTNGAYGAYAGYGAYGARGTNAAYGAR ACNGARCARYTNYTNAAYATHGARAGYYTNGGNTCNTTYGARATHGTNGARCAYGARACN ACNGCNGGNYTNACNACNGARGTNGAYCCNAARTGGTCNCAR---------GGNAARTCN AGYAGYGGNGARACNMGNGTNACNGCNTCNGCNTCNACNGARGARTGYACNGARAAYCCN GGNAGYCARGARGTNACNACNGCN------------CCNACNCCNCARTCNAAYATHCCN CCNACNCCNCARGAYGGNAGYGTNCCNACNCCNMGNGAR---AAYTAYACNGARGAYAGY GTNATHCARGARCCNGGNTCNATHAGYAAYGTNGAYATHTTYTCNCCNTCNATHTCNACN ---CCNAGYAARCCNAARAARAARAARAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GTNACNTCNTCN GTNGGNACNTTYCAYGGNTCNGTNYTNACNTCNTTYAGYGGNCARCCNTTYACNGCNTTY MGNGGNATHCCNTTYGCNYTNCCNCCNGTNGGNCCNYTNMGNTTYGARAARCCNCARCCN TAYCCNAARATHGARGGNATHTAYGAYGCNACNCARACNAGYCCNATHTGYATHCARCCN MGNGAYATHGAYTTYGGNCARCCNGGNCARGARGAYTGYYTNTAYYTNAAYGTNTTYGTN CCNTTYAARGGNCARGARNNNNNNNNNNNNAGYYTNAARAARGTNTTYNNNTTYATHCAY GGNGGNNNNYTNTTYNNNGGNTGYGCNAAYCARCAYNNNCCNGGNGAYYTNGTNTCNCAR GGNGAYATHATHGTNGTNACNATHAAYTAYMGNYTNTCNTGGYTNGGNTTYGTNAAYTGY CCNAGYAAYGARATHCARGGNAAYATGGGNYTNTGGGAYCARYTNATGGCNYTNAARTGG GTNMGNGAYAAYATHCARGCNTTYGGNGGNGAYCCNGARGAYATHACNGTNGGNGGNGAR TCNATGGGNGGNGARTGYGTNTCNGCNYTNAGYATHGTNCCNCARGCNAARGGNYTNTTY ACNAARGGNATHYTNATGAGYGGNACNATGTTYACNTGYTCNTCNACNCCNGGNTCNTCN GAYTTYYTNYTNMGNAARYTNGCNACNCAYYTNGGNCCNGAY---------GARAARTCN GARYTNATHGARGARATGMGNAARYTNCAYGARGAYCAYTTYATHCARCCNGTNGARMGN CARATHATHAARCAYTTYACNTCNATGGAYGGNGARYTNTTYCCNGCNTCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GTNGAYAGYYTNCARMGNCARYTN GGNGGNTAYGGNMGNTAYCARATHYTNATHTAYGTNYTNYTNGGNYTNGTNTAYATGMGN GGNTGYTGGCAYGCNYTNGTNCCNATHTAYCARGGNGTNGTNCCNGARCAYTAYTGYMGN CCNYTNCCNGGNYTNCCNYTNAAYGARTCNGAYCCNGGNCARCCNGGNGCNAARTCNTGG ACNGTNGAYCARTGYCAYCARTAYATHAAYTTYAGYAAYAGYAAYGCNACNGARCCNTGY ACNMGNAGYTGGGTNTTYGCNTGGGARGAYAAYGAYACNTCNTCNATHGTNTCNGARTAY TCNYTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR ATGAARGTNAAYTGGGCNGCNTCNCCNAGYACNGCNCCNAARCARGAYACNAGYAARCAY TTYCAYGTNTTYGTNGGNGAYYTNAGYTCNGAYATHGARCARCAYCARYTNMGNGAYGCN TTYTCNATHTAYGGNGARATHTCNGAYTGYAARATHATHMGNGAYCCNGCNACNATGAAR TCNMGNGGNTAYGGNTTYGTNTCNTTYATHAAYAARCARGARGCNGARAGYGCNATHTCN GGNATGAAYAAYCARTGGYTNGGNACNMGNCCNATHMGNACNAAYTGGGCNACNMGNAAR CCNYTNGCNCCNGTNGTNAARGARAAYGCNAARCCNYTNGTNTAYGARGARGTNTTYAAY CARTCNAGYTCNACNAAYTGYACNGTNTAYTGYGGNGGNGTNACNAAYGGNYTNACNGAR GARYTNATGMGNAARACNTTYTCNCARTAYGGNACNATHCARGARGTNMGNGTNTTYAAR GAYAARGGNTAYGCNTTYATHMGNTTYAGYACNAARGARTCNGCNACNCARGCNATHTGY GCNGTNCAYGGNACNACNGTNATHGARCARCCNGTNAARTGYTCNTGGGGNAARGARTCN AAYGAYTCNAGYCARTCNACNCARCARTCNTCNAAYCCNCCNGTNGTNATGGTNCCNTCN CARCARCARCARCCNATHGCNGCNAGYCCNGCNGCNGCNCCNTAYGGNGGNCAYTTYTAY AAYATGAGYTAYTAYCAYGGNACNCCNTAYGCNGCNGGNGCNCCNACNTAYCCNAGYCCN GTNCCNGCNCARGGNCARTAYATHCCNGCN------AAYCARTGGCCN---GGNTAYTCN AGYTAYCARGCNTAYGGNAGYATGAAYGTNCCNATGGGNCARTAYGCNGGNATHCARATG CARCCN---GGNCARCARCARCARTTYAAYGGNCARAGYCARGGNATHGTNGGNTAYCCN ATGCARCARGGNATGGCNMGNTCNAAYGTNMGNTAYGARGTNYTNCCNTCNGARGARCAR AAYGTNGCNGCNGARCCNGTNGCNATGGCNACNGTNGTNCCNCCNCCNGGNTAYTCNGAR ACNGCNGTNTTYGARCARCARGGNGAYACNCCNGCNTAYGGNCCNGCNAARYTNCCNAAY TAYGTNGARGCNACNACNYTNCCNTCNTAYGARGARGCNGARMGNAGYAARYTNGARGAY GARGCNGCNACNACNCCNCARAAYGGNGAYTGYGARTCNGGNMGNYTNTTYGGNGTNGAY GGNGTNACNGARGTNGCNATHGGNACNGAYGGNATGTTYATHTGYACNTTYTTYATHTCN TTYYTNTTYAAYTGGYTNGGNTTYYTNYTNTCNYTNTGYYTNTCNAAYACNATHGCNGGN MGNTGYGGNGCNYTNTCNGGNYTNGGNYTNTCNATHGTNAARTGGGTNGTNATHGTNAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNCARAAY TGGYTNGAYATHAARTCNYTNTAYCAYGTNGCNAAYTGGMGNTTYMGNGCNGTNGCNGTN GAYYTNCCNGGNTAYGGNAARAGYGCNAARACNYTNGARGTNGARCAYAGYGCNGCNTTY YTNACNTCNYTNATHTCNGTNYTNAARYTNGGNAARCCNGTNATHGTNTCNCCNTCNATG AGYGGNGGNTTYTCNYTNCCNTAYYTNTTYGARGAYGGNGCNACNAGYACNGARMGNGCN TCNGGNTAYGTNCCNGTNGCNCCNGTNAGYACNYTNCARTTYGTNGARCARTAYAARAAR AGYCARYTNCCNTGYYTNATHGTNTGYGGNACNGAYGAYMGNTCNYTNGGNACNCARTCN ACNGARAAYYTNAAYCAYYTNCCNAARGGNTGYTAYGCNCCNATHCARGAYGCNGGNCAY GCNTGYTAYYTNAAYAAYCCNGAYGCNTTYCAYAARYTNYTNTAYCAYTTYYTNAAYCAR YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNTCNGCNGCNAARCCNMGNAAYTGGYTN YTNGCNTCNCCNTAYGAYATGGGNGTNAARTGGYTNGGNGARGGNYTNYTNATHGCNAAY GGNGARAARTGGAGYMGNAAYMGNMGNYTNYTNACNCCNGCNTTYCAYTTYAAYATHYTN AARTCNTAYGTNAGYGTNTAYAAYGARTGYTCNTCNYTNYTNGTNCARCAYATHMGNAGY GAYAARAARGARGCNTTYGAYATHTTYGGNCCNGTNAGYYTNAGYTCNYTNGAYGTNATH YTNMGNTCNGCNTTYTCNTAYAARTCNGAYTGYCARACNTCNGARGARYTNAAYGTNTAY GARCARAGYYTNACNGARYTNATHGGNYTNTGGACNGCNMGNTTYTTYAARCCNYTNGTN TTYAAYGAYTTYATHTAYAGYYTNACNTCNTCNGGNMGNMGNTTYTCNCAYYTNTGYAAY GTNGTNCAYAARATHGCNGARGARATHATHYTNCARMGNAARGARTCNYTNGCNAARGAR AAYTCNACNGAY---------AAYAARAARGTNAARGAYTTYYTNGAYACNYTNYTNACN GCNMGNGAYGARAAYGGNGARGGNATGTCNATGATGGAYATHMGNAAYGARGTNGAYACN TTYYTNTTYGARGGNCAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR AAYGARAAYGTNYTNAARATHACNCAYCARYTNCARGARTCNYTNCARCARGCNATHGCN YTNCARAARGCNYTNTTYACNAGYTGYGARMGNGARAARTGYAARGARGARGTNYTNTAY TCNYTNMGNAARCARCARAARMGNACNATGCARGARYTNGCNAAYYTNMGNGARGTNTAY GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNGAYATGGTNAAYMGNGAYCCNAAYAAYYTNAAYGAYCAYATHMGN GTNYTNTTYGARGAYGTNATHGCNGARCCNGAYGGNGCNCAYTCNATHGGNTGYGTNTGG GCNAGYTCNTAYTTYTGYTTYAAYTGYTGYAARAAYATHTGYTAYAARGTNATGACNYTN TTYTGYGGNGTNCCNYTNGCNATGTGYTGGGGNATHGARTTYGCNYTNATHACNTTYAAY CAYGTNTGGTAYATHACNCCNTGYATGMGNYTNTAYATGATHGARTGYGGNTCNTGYMGN AARTTYTAYGGNACNTGYYTNCARTGYTGYATGCARCCNTGYTTYGARGCNATGAGYTCN TGYTTYGGNAAYATHAARGTN------------CARMGNAGYMGNGARGARGAYYTNMGN ACNAARGTNATGACNYTNGARAAYCARGTNGCNAAYAARCARGGNGAYATHGAYMGNYTN GARMGNATGYTNGAYGTNGTNAARCARGARTGYAGYGCNCARYTNGTNGAYAARGTNACN AGYGTNGARTGYMGNYTNAARYTNCARYTNGARGARAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AGYAARGCN---TCNAAY TGGAAYCARGARACNAARGCNMGNYTNAAYGARMGNATHACNATHAAYATHAAYGAYATH GCNTCNYTNACNMGNCARGTNATHMGNGGNTCNAARACNAAYGARTTYYTN--------- ------GCNCARGCNGCNAARAAYTTY---GTNTCNCARGARAGYTAYATHCAYAAYTCN TTYGARACNATGAARAARGTNMGNTCNCARYTNGARTTYCAR------------------ ---------------------------------CARTCNGCNATHGCNMGNAGYYTNCAY CAYYTNGAYGARGTNCARGAY--------------------------------------- ------------------YTNTAYMGNCCNGAYGAYGARGTNGTNATHTTYCAYTGYTCN CARTTYCARYTNCAYGTNGGNYTNCCNGGNATGGCNGTNAAYGTNGAYCARGTNAGYAAR ACNGTNCARAARGCNAARTCNGARTCNGARAARATHACNGGNGARGCNAAYGARATGYTN AARACNMGNGGNGTNAARGGNTAYGTNGTNGCNGTNCARAGYTCNAARCCNGARGAYGCN ATHYTNAARGCNATHGARTCNGARGGNGTNGAYCARGTNGTNATGGGNACNMGNGAYYTN GGNAGYATHAARMGNGCNYTNGTNGGNAGYGTNAGYACNGCNGTNGTNMGNCAYGCNAGY GTNCCNGTNACNATHGTNAARYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARAARACNATHCAYTTYAGY GGNACNMGNTAYMGNGARATHAAYAARMGNYTNGARMGNTTYYTNAAYAARMGNAARGTN TTYCCNGAYTTYCARGAYGTNAARACNATHATH--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNAARYTNGTNMGNCARYTNGGNAGYYTNGARATHATHAAYGGNAAR------GAY TGYCARCARAGYGARCAYGCNACNGGNMGNCCNCCNTCNGTNTCNTCNTCNMGNTCNTGG TCNMGNTCNAGYGTNGGNTCNGTNCCNCCNMGNCCNGAYTCNTCNTCNAGYMGNMGNACN ATHACNCCNACNAARCARATHTCNYTNCARGCNGTNAARMGNAARGARGARAGYTCNGAY CCNTTYGTNGAYCAYGTNGAYYTNAGYTCNYTNAAYTTYGAYGCNGGNTAYCARMGNATG MGNGARTGGCCN------------GARGARCARGAYAARMGNACNCCN---------YTN AARMGNTGYYTNGARACNGAYGARGGNAARAARCAYAARMGNTTYGTNGARGAYGTNGAR GCNGCNYTNGCNCARACNGAYGCNTGYGAYGCNAARGCNGGNAARGAYGARTGYGCNGAY GCNGAYAARGARATGGARMGNAARGAYGCNGCNGAYTCNAGYTCNGAR---GAYGARGAY GARGGNAAYAARAARGTNACNYTNMGNGCNCCNAAYGARYTNYTNATGGARTTYGTNGAR TGYYTNATGAARAARGAYTTYYTNAAYGCNGARAARYTNTGYAARATGATHYTNYTNTAY GARCCNGARAAYCCNGARGCNYTNAARTTYCARCCNYTNATHGARGARAARATGAARYTN GAYGCNGARGCNGCNGCNGCNGARGARGARGAYGARGAYAGYGAYGAYGARGAYAGYGAY GAYAGY---GAYGAYAGY------------------------TTYCARATGTCNGGNYTN GAYGTNGCNAARAAYMGNATHYTNGARATHGCNTGYYTNGTNACNGARAAYGAYYTNTCN ATHGTNGARGARGGNCCNAAYYTNGTNATHCAYTAYGARGARTCNGTNYTNTCNGGNATG GAYGARTGGTGYATHGARCARCAYGGNAARTCNGGNYTNACNAARTCNGTNMGNAARTCN AARATHAGYACNACNGAYGCNGARGARAARATHATHCARTTYYTNCARMGNCAYACNCCN AARGGNYTNTGYCCNYTNGCNGGNAAYTCNGTNGGNATGGAYAARMGNTTYATHGAYMGN TAYATGCCNYTNYTNGGNGCNCAYYTNCAYTAYMGNATHGTNGAYGTNAGYACNGTNAAR GARYTNTGYMGNMGNTGGCAYCCNAARYTNTAYGAYAARAARYTNTCNCAYMGNGCNATG GAYGAY---ATHAARGAR------------------------------------------ AGYATHGARGARYTNAARTAYTAYMGNTCNGCNATHTTYAARGTNGAYMGNGARGAYACN TAYGGNACNCAYMGNTTYGAYTGYCAYTTYGGNACNACNTAYAARATHGTNGTNGTNCCN AAYGARGCNGCNACNTTYYTNTCNTGYGGNGAYGAYGGNACNGTNMGNTTYTTYGAYYTN MGNGTNAARACNAGYTGYACNAARTTYAAYTGYGARGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNATHGARAAYMGNGAR ATHATHTCNATGMGNATH---GGNYTNAAYAGYAAYGAYCARAARCCNGTNGTNYTNYTN GAYGCNGGNATHCAYGCNMGNGARTGGATHGCNCCNGCNACNGCNYTNTAYGTNGTNAAY GARYTNGTNACNAARTAYMGNACNGAYGCNAGYATHGCN---GCNYTNGTNGARAARTAY GAYTGGTAYGTNATHCCNGTNGCNAAYCCNGAYGGNTAYTCNTAYACNTGGACNTCNAAY ------MGNYTNTGGMGNAARAAYMGNTCNYTNTCNAGYAAYGGNTGYTAYGGNGCNGAY CCNAAYMGNAAYTTYCARYTNGGNTTYGGNGCNTCNACNAGYACNAAYCCNTGY---TCN GAYATHTAYCCNGGNMGNTCNGCNTTYTCNGARCARGARTCNCARGCNATHMGNMGNYTN ACNGARGCNCAYATHGGNAAYGTNMGNGTNATHYTNACNYTNCAYTCNTAYGGNCARATG TGGATGACNCCNTAYGGNTAYACN---MGNCARMGNCCNTCNGAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGACNGTNAARTAY ATHGCNGTNTCNATHATHTTYYTNTTYAAYTCNGCNYTNGGNAGYATGYTNGGNATHGTN GTNACNCCNACNYTNATHYTNYTNTTYGTNGGNGARAARGTNGARATHCCNACNGARAAR ATHTTYCARCARYTNTTYATGACNGTNGTNGTNCCNYTNATHATHGGNCARATGGTNMGN AAYTAYAAYTAYMGNTGGYTNCARMGNYTNAAYATHCCNTTYAARACNATHGGNCAYYTN YTNATHYTNTTYATHATHTAYACNACNTTYTGYGCNACN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATHATHAARYTNMGNAARGCNYTNAAYAARTCNACNYTNGAYATG GAYTCNGCNAARAAYMGNTTYCAYAAYGCNGTNMGNCARTCNCARGTNCCNGGNGTNAAY ATHGCNACNACNGCNGCNAARGCNGAYGTNATHMGNGARCARYTNGARGARGCNTCNTCN AARGTNGARACNATHAARGAYAAYYTNTCNATHGARYTNTGYAAYTTYGCNGCNAARGAR AGYGAYCAYACNTAYAAYYTNYTNGTNTTYYTNGARGCNCAR------------------ ------------------------------------------------------------ ------------------------------------GTNTCNCCNYTNCARGAYCAYGAY TTYTTYTAYTTYGTNMGNGCNGAYATGAGYYTNGGNTCNAAYGCNTTYACNMGNGCNTAY GTNAAYTTYATHAAYGCNGARGAYATHTTYATHTTYMGNGAYAARTTYGAYGGNTAYGTN TTYYTNGAYGCNAARGGNGGNGARTAYCCNGCNATHGTNGARTTYTCNCCNTTYCARAAR GTNCCNAARAARAARTCNMGNAARATHGAYGCNAARAAYGGNATHATHGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TGYGARAARTGYCARTGYAAYGCNCCNCCNMGNTCNCAYCAYTGY AARYTNTGYAAYMGNTGYATHYTNAARMGNGAYCAYCAYTGYTGGTTYGCNGGNTAYTGY GTNGGNTAYGCNAAYCAYMGNTAYTTYGTNGCNATGACNTTYTAYATGACNGTNGCNGCN ACNTAYGCNAAYATHTAYAAYTGGGAYTAYGTNATGGCNATGAARGGNGGNTTYGGNTGG ACNACNATHYTNAGYTTYATHGCNCCN--------------------------------- ---------GARMGNATHMGNGGNGGNGGNGARYTNTTYAARTAYCARTGGACNACNTTY TCNMGNGTNCARCARTTYCCNTTYAARTTYTAYTGGACNCAYGCNMGNCCNTTYMGNTAY TTYATHTAYAGYTCNATHYTNATHTTYCCNYTNATGGTNAARYTNACNAARGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNACNCAYCCNGGNACNCCNATHATHYTNGGNCCN MGNYTNCCNCCNCCNACNGTNGTNGCNACNTCNCCNCCNAGYATGAAYGGN---GCNCCN CCNCCNYTNGTNTCNCCNCAYGGNGARGCNGCNAGYYTNATGTAYAAYCCNTAYGCNGTN GGNGCNATGGGNGGNATHGGNCCNGCNGTNCAYTCNCCNATGGAYCCNTAYTGYTTYGGN GTNGCNACNCCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNCCNGCN CARYTNCARMGNYTNYTNACNATHYTNAARGAYAARGTNAAYGGNYTNAGYYTNGARGCN AGYATHGTNMGNAAYAAYGCNATGGAYACNATHGAYCCNACNGARAAYYTNAAYAARGTN GAYGARGARACNYTNCARMGNAARAARYTNCARATGGAYTCNTCNTTYGARAARAAYMGN AARMGNCCNGGNGAYCCNGAYTTYGARTAYAAYGTNGARGTNGAYTTYGARATHGGNGGN GTNGARACNAGYGGNTGGGAYTCNGARGGNTCNGAYGTNGAYTTY >columbiana ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GTNAAYGAR GCNAARAARMGNATHTCNYTNGTNGCNAARAARTCNCCNCAYATHATHCAYAARMGNTCN GARAGYGGNGAY---GTNAAYCCNTAYYTNCARGGNATHAARATGMGNMGNGCNGCNAAR AARAAYCAYGARATGGCNCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARCCN CCNAARGAYAARYTNTAYMGNCARGTNATHGTNGARGTNAARGGNCAYGAYCCNGCNGTN ATHAAYAGYTAYCARAARTTYACNACNGCNACNGCNGARCARYTNGGNGTNACNATHGCN AGYATHACNGARCCNCCNAARGTNATHACNMGNAARAGYYTNYTNAARTCNGTNTTYGTN TTYAARAARCAYCARCAYCARTAYGARCARMGNACNYTNTTYMGNGTNTTYGARYTNAAR CAYYTNACNGARTCNACNGCNYTNACNTTYYTNGARTAYATHCARMGNAAYYTNCCNGAR GGNATGGCNATGAARGTNACNAARCAYGARYTNMGNCCNATHCCNGARCAYYTNAARCCN CCNGARAAYGCNMGNYTNGGNGARGTNGARCCNTCNGAYTAYTTYAAYGTNATGYTNGGN ACNCARYTNYTNTAYAARTTYGARMGNCCNCARTAYAGYGARATHYTNTCNGARAAYCCN GAYAARTGYATGTCNAGYATHTAYGGNGCNACNCAYTTYYTNMGNYTNTTYGTNMGNYTN GGNGCNATGYTNTCNTAYTCNACNYTNGAYGARMGNACNGTNCAYATHYTNYTNAAYCAY GTNCAYGAYTTYYTNAARTAYATGTCNAARAAYGGNGCNAGYTTYTTYAARACNGCNAAY TAYGARATHGCNTCNCCNGAYTAYCAYMGNAARGCNATH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CARMGNTGGATHCCNYTNGAR TCNAAYCCNACNGTNYTNAAYAARTAYGTNCAYAAYYTNGGNATGGAYAARGARTGGAAY TTYGTNGAYGTNTTYGGNYTNGAYGCNGAYYTNYTNGCNATGGTNCCNMGNCCNGTNGCN GCNGTNGTNYTNYTNTTYCCNAGYACNGAYCAR------------ACNGAYGARAGYGGN GARYTNATGAARGAYATHCCNGAYGAYYTNTAYTAYACNAARCARACNATHGGNAAYGCN TGYGGNACNGTNGCNATHGTNCAYGCNYTNGCNAAYAAYGCNTCNMGNATHAAYTTYGAY GCNGARAARCAYTTYMGNACNTTYATGTCNGCNACNAARGCNATGAGYCCNGARGAYAAR GCNACNCAYYTNGARTCNGAYYTNYTNATGGGNTCNGCNCAYGARGARAGYGCNCARGAR GGNGAYACNGCNGCNCCNGARGCNTCNGARAARGTNAARTGYCAYTTYATHGCNYTNGTN AAYTTYAAYGGNAGYYTNGTNGARYTNGAYGGNMGNAARGARGGNCCNGTNACNCAYGGN TCNACNAARGARGAYTCNTTYYTNGARGAYGCNGCNGTNGTNATHAARAARTTYATHGAR MGNTGYCCNTAYYTNGCNGCNMGNAARGCNYTNTCNGAYAARGAYAARAGYACNGTNATG GGNCAYAARYTNCARATGAAYGAYGAYGARCARYTNGTNTCNGAYTCNATGGTNAARGAR AARTCNGCNYTNATHGARAARAGYMGNATHGGNMGNGAYACNTAYTTYCCNGCNATGAGY TAYTTYAARTCNAARCCNYTNATGGARAARACNAAYACNTAYMGNATHATHCARGAYATG CCNAARGGNGGNGTNYTNCAYYTNCAYGAYATGGCNATGACNAGYYTNGAYTGGYTNATH TCNAAYATHACNTAYMGNGAYAAYYTNTAYATGTGYGTNGAYGARAAYACNYTNATHACN TTYCAYTTYTTYAARACNGCNCCNGCNAAYCCNGGNTGYGARTGGAARYTNGTNAARATG GARMGNGCNATGGCNGCNAAYATGACNCARTTYGAYYTNAGYYTNAARAAYAAYATGAGY YTNGTNGCNACNGAYCCNTTYGTNACNTAYCCNACNYTNACNCARGTNTGGAAYAARTTY GGNTCNTAYTTYGGNCARGCNTTYGGNYTNATHTTYTAYAARCCNGTNTTYAARGAYTAY TTYCARMGNGGNYTNAARGARTTYYTNAAYGAYAAYGTNCARTAYATHGARYTNMGNTGY YTNATGTCNAAYYTNTAYGAYYTNGARGGNAAYGTNTGGGGNACNMGNGAYACNTTYGAY YTNTAYCAYACNGCNYTNGARGARTTYAARAGYGARCAYCCNGARTTYATHGGNGTNAAR TTYATHYTNTCNGGNGAYMGNTCNAARAAYCCNGAYGCNATHYTNAARGGNGTNAARGAY ACNATHTAYYTNMGNCARAAYCAYCCNGAYYTNATGYTNGGNTAYGAYYTNGTNGCNCAR GARGAYCCNTAYAAYACNYTNCARTAYTAYYTNAARGARYTNYTNTAYCCNAGYCARYTN AGYCCNCCNGTNGAYYTNCCNTAYTAYTTYCAYGCNGCNGARACNGAYTGGCARGGNACN GGNACNGAYAAYAAYYTNYTNGAYGCNATHYTNYTNAAYACNACNMGNATHGGNCAYGGN TAYGGNYTNAAYAARCAYCCNACNYTNGTNAARGARATHAARAARMGNGGNATHGCNATH GARGCNAAYCCNATHTCNAAYCARYTNYTNGGNYTNTAYAARGAYCCNMGNAAYCAYGCN YTNATHCCNYTNATHGCNGAYGAYTTYCCNATHGTNGTNAGYTCNGAYGAYCCNCCNGTN TGGGARGCNGCNCCNYTNTCNAGYGAYTTYTAYGTNGCNTTYATGAAYATGTGYGGNGAR GAYAAYTGYYTNMGNTTYYTNAARCARYTNGCNATHAAYTCNTTYCARTAYAGYGGNATG ACNCARCARGARAARCARGCNGCNYTNAARACNTGGCARAARAARTGGGAYGCNTTYATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MGNMGNGCNYTNGCNATGATGMGN YTNGGNAARAARTAYTAYGGNCCNTCNYTNGARATGGAYMGNMGNCARGAYGARAAYYTN AAYAGYGAYTTYACNGAYGGNGAYGAYAARMGNGGNATGTCNYTNYTNMGNYTNGGNAAR AARTCNATGAARYTNYTNMGNYTNGGNAARAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATHCCNACNMGNTCNGCNGARGAYACNYTNCARGAYACNTCNTCNYTNGTN YTNGAYAARMGNCCNAARTAYATGGAYACNMGNMGNGAYYTNGAYATHTTYAARGAYYTN GTNYTNACNAGYATHCARGARYTNGTNGAYGARGGNMGNYTNGARTCNTCNGTNYTNCCN GARGAR------GAYMGNGARACNAGYCARCCNATHGARAARMGNMGNTAYATGGGNYTN TGYATGCAYMGNCARGCNAAYCARTAYATHCCNTTYCCNTGYYTNMGNACNGGNMGNATG AARGCNCARTTYTGYATHTTYATGATHYTNTTYGCNACNGTNTTYGCNGAYAAYTAYYTN TGYCCNCCNAARAAYGGNGAYAARTTYGARTGYTTYGARTCNYTNAARAGYCAYMGNAGY TGYYTNACNAAYGCNMGNMGNACNGARACNAARGTNGTNTGYGGNAARTGYACNMGNAAR TGGGARTTYTGYGTNACNMGNGGNGAYYTNCARAARTCNAARAAYCCNGARMGNGAYTGY GGNCCNGAYTAYAARTCNACNGARTGYACNGTNGCNAAYTCNTAYTGGTCNGGNGCNTTY YTNTCNYTNYTNGAYYTNAGYCCNGTNACNAAYGGNTTYATGTTYTAYMGNGGNGAYATH CCNAAYGGNTTYAAYGTNCCNGAYCCNTGYCAYCCNGGNAARACNATHCCNGGNGTNGGN CAYGTNAAYAARGTNGGNGGNGGNCARAAYAAYCARTTYGGNGTNGAYTTYAGYTAYTCN AAYCAYATHTGGACNGARACNYTNTGYAAYCARGAYTCNGAYGGNGAYGGNAARTCNAAY GGNGARGARYTNGGNGAYCCNAAYTGYGTNTGGCARYTNGGNGAYACNCCNGCNMGNATH ACNGAYYTNAGYCAYCCNGGNATHGAYAAYAAYAGYCCNGGNTGY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GGNACNTCNAGYGGNGTN TTYTAYATHCCNGGNTCNGTNGTNAGYTAYCCNAARATGGGNAARMGNGCNTTYTAYACN AAYGCNACNGGNAAYMGNTAYCCNATGATGGGNMGNMGNTCNTCNTCNGAYGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GCNGAYTAYGARAGYTAYTGYACN--- AGYTAYGAYATHACNCAYGGNMGNGGNMGNTGYGGNCARGARYTNGCNAAYATHATHTTY AAYYTNTGYAARGTNYTNGGNGGNGTNAAY------ATGAARACNMGNYTNGTNAARMGN AAYACN---------AAYGARGGN---ATGGAYGARATGTTYATGGAYAARAARGAYGCN TTYTCNTTYYTNGCNAARMGNTCNYTNACNCARGGNGTNATHTGYGARTGYTGYGTNAAY ACNTGYACNACNTAYGARTAYGCNCARTAYTGYGARATHTTYGAY--------------- ------------------------------------------------------------ ---------------------------------MGNTAYGCNCCNMGNTTYATHGGNAAR MGNTAYGGNCCNMGNTTYGTNGGNAARMGNTAYGCNCCNMGNTTYATHGGNAARMGNTAY GCNCCNMGNTTYATHGGNAARMGNCARCCNMGNTTYGGNAARMGNTAYGCNCCNMGNTTY ATHGGNAARCCNMGNTTYGTNGGNAARAARGCNGARGARYTNAAYGARGAYATGAAYGAY TCNTTYTCNYTNCCNGAYYTNGAYGAYACNAAYGCNTTYAAYGAYGGNYTNTTYGAYGAR TTYGGNTAYGARMGN---YTNACNAARMGNGCNCCNCCNMGNTTYGTNGGNAARMGNGGN GCNCCNMGNTTYATHGGNAARMGNGGNCCNCCNMGNTTYGTNGGNAARMGNAAYGCNCCN MGNTTYATHGGNAARMGNAAYAAYGAY---------GTNGAYGARTAYGAYATHYTNMGN ---------------------TGGGGNYTNCARAAYAGYAARMGNCARGCNCCNMGNTTY ATHGGNAARMGNTCNGGNGAR------------------TGGGAYCARYTNYTNAARGAY TTYGCNMGNAAYGARGCNATHCARACNTAYMGNTCNGGNGAYAARMGNTGGAGYACNCCN GTNACNCCNGGNTTYATHGGNAARMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYTCNGGNAGYYTNATGGCNAAYATGGCNGGN YTNTAYAARAGYGGNTTYACNGTNAGYGGNAARCARMGNTAYATGYTNAGYACNCARTTY GARGCNAGYCAYGCNMGNMGNGCNTTYCCNTGYYTNGAYGARCCNGCNYTNAARGCNACN TTYAARYTNTCNGTNGTNMGNGAYGAYGAYCAYYTNTCNATHTTYAAYACNAARCCNGTN MGNTCNGARCARGGNAARAARGGNYTNACNYTNGAYGTNTAYGARCCNACNGTNTGYATG TCNACNTAYYTNGTNGCNTAYGTNATHAGYCAYTTYAARAARGTNGCNACNAAYACNMGN GAYGGNYTNYTNATHCARGTNTAYGCNCCNGARGAYAARATHTAYATGGGNCARTTYGCN YTNGAYGCNTCNGCNATHATHATHGARAARTAYAAYTCNTTYTTYGGNATHCCNTAYCCN YTNGAYAARYTNGAYYTNATHGCNATHCCNAAYTTYGCNGCNGGNGCNATGGARAAYTGG GGNYTNGTNACNTAYMGNGAYACNGCNYTNYTNTAYGAYCCNGAYAARTCNACNATHTTY ACNAARAARTAYGTNGCNYTNGTNGTNGCNCAYGARYTNGCNCAYCARTGGTTYGGNAAY YTNGTNACNATGAARTGGTGGAAYGAYYTNTGGYTNAAYGARGGNTTYGCNTCNTAYGTN GARAAYATHGGNGCNGAYACNGTNGAYCCNAGYTTYMGNATGTTYGAYTCNATGGTNTGY GGNGGNMGNGAYACNYTNAARYTN---GAYGGNGTNAGYTCNTCNCAYCCNATHGARGTN AARGTNAARGAYCCNGTNGAYGTNGARGCNGCNTTYAAYACNATHACNTAYCAYAARGGN GCNCAYYTNATHCAYATGYTNMGNGGNGCNATHGGNAARAAYGARTTYCAYGARGGNYTN AAYTAYTAYYTNAARMGNCAYGCNTAYAAYAAYGCNGARACNAARGAYYTNTGGAARGCN TTYAARCAYAGYCAYYTNAAYGGNYTNACNGTNTCNGAYTTYATGGAYACNTGGACNCAR CARATGGGNTAYCCNGTNGTNACNGTNACNMGNAAYAAYAARCARATHTAYYTNCAYCAR GARMGNTTYYTNATHAAYAARGCNGARGAYCARCARGAYGCNCAYAAR------------ TAYTCNTGGCAYATHCCNTTYAARTAYAARYTNTCNCCNGAYCAYGARACNGTNYTNACN GTNTGGYTNAAYAARGGNAAYGCNTCNATHCARYTNCCNMGNTCNGCN---TGGYTNAAR GGNAAYGCNGAYAGYGARGGNTAYTTYMGNGTNAAYTAYGAYGARGARGGNTGGAARGCN YTNTCNGAYCARYTNGARAAYAAYCAYACNGTNTTYTCNCCNYTNGAYMGNGTNAGYYTN ATHGAYGAYGCNTTYGARYTNGCNAARTCNGGNMGNYTNACNTAYGAYATHGTNYTNAGY YTNTGYYTNTAYYTNMGNAARGARACNGAYTAYTTYGTNTGGMGNACNGTNAARGAYCAY YTNATGTAYYTNCARCAYMGNYTNTAYYTNCAYGARGCNTAYGAYGAYYTNAARGTNTTY ATHYTNCAYATHGCNAARCCNYTNTTYGAYTCNGTNGGNTGGGAYAAYAAYGGNACNTTY TCNCARMGNYTNYTNMGNMGNGARATGYTNGAYYTNGCNGCNAARYTNGARTAYGARCCN GTNACNAAYAARGCNAAYGARTGGTTYGARAARTGGATHAARGAYGARAAYAARYTNAAY TAYGAYYTNACNCAYATHATHYTNAAYGTNGGNGTNMGNTAYGGNAARAARTCNGAYTGG AAYGTNGTNTAYGARMGNTAYYTNCAYGARAAYATHCCNTCNAARAARTCNACNYTNATG YTNGCNYTNACNACNTCNMGNGAYCCNMGNGTNYTNCARATHYTNYTNGARAARAGYYTN GAYACNACNGTNATHAARTCNCARTCNACNATGTCNATHYTNTCNGGNATHTCNMGNAAY CCNGTNGGNYTNYTNCAYGCNTGGMGNTTYGTNGARGARAARTGGGAYGTNYTNTTYCAR MGNTAYGGNTCNAGYTCNTTYAGYYTNTCNGAYATGATHAARAAYGTNATHGGNCARTTY AGYACNCARTTYGAYYTNGAYCARGTNATGTCNTTYTTY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNCCNTCNGGNACNCCNCCN CCNAAYCARCARYTNTAYCCNGGNCCNTCNCAR---GGNCCNGCNTTYAAYTTYATHCAR GGNCARTAYCCN---------CARAGYGARCARYTNYTNTCNTAYCARGCNTAYGGNAGY GCNCCNAAYGAYYTNMGN---GGNCCNAAYCCNAGYGGNMGNGGNGGNGGNCCNGCNAAY ---ATGGCNCARTCNGGNTCNTAYTAY---CARACNGGNCARAAYATGMGNCCNTCNCAR ------CCNCCNCCNCCNAAY---CCNTAYTAYATHGGNCARACNAAYCARGGNGCNATG MGNCAYCCNMGNCCNACNCAYGGNTCNGCNAAYCARCCNATHGTNTTYGTNCCNAAYACN AAYAAYATGGTNATHTCNAAYATGTAYCARCAR---GCNMGNATGCCNATGTAYCCNCAR GGNGCNCCNCARTTYCARTCNMGNTAYAGYCARCCNAGYGCNGTNATG------------ TAYTTYAAYGGNGTNCCNMGNACNTCNGTNACNCARGCNCCNGGNCCNMGNGARAARMGN ATHATHAAYATHAGYGAYCCNGTNACNGGNMGNAAYATHACNGAYGARATHATHAAYTCN TCNCAYTCNGCNGARGARAARCCNGTNGCNGARGARTCNTCNATGAAYGAYAARGGNGTN GARATHMGNAARAAYTTYACNMGNCARGTNGTNGARMGNATGAARACNGGN---GARTTY GCNACNCCNGCNCARCCNGCNACNGAR--------------------------------- ---------------------AAYCARCCNAAYATGGARCAYCCNCAYACNTCNTAYCCN TCNGGNCCNTCNCARCARGTNCARTCNAAYCCNTCNYTNGTNTCNGTNGCNCCNGTNCCN GGNTCNYTNGTNMGNCCNCCNATHAGYCCNGCNATHAAYYTNAGYGTNCCNCCNCCNCAR YTNCCNGCNAAYATHCCNCARACNAAYTCNGCNCARGCNCAYCCNCARTCNCAYCCNCCN ATGCCNCCNCCNAARGAYATHATHACNCARGTNGAYTCNGTNGAYACNGARCCNACNCCN ACNTCNAAYGTNTCNGCNATHCCNGTNYTNACNCCNGAYYTNCCNATHGAYTCNAGYGTN GARACNTCNGTNGCNTCNATGTCNYTNCCNTCNAAYGARCCNAGYACNATHACNGTNCCN GTNGAYATHGTNTCNGAYGARGCNACNATHGARCARYTNACNGARCAR------------ ---GAYACNCAYGCNGTNGTNAARGARGAY------------------------------ ---GCNGTNTCNGGNACNACNAAYCARAGYACNAARGAYGTNMGNAARGGNAARAARAAY AARAARGAYTTYAGYCARAARGARAGYGGNGGNTCNGARATGGAYGCNTTYATHGAYGGN AARGAYAGYGGNGTNGAYTCNGARCCNGGNCAYCCNAAY--------------------- ---------------------------------------------------------GAR GCNMGNATHCCNGARGAYGTNTCNGTNTCNGTNATGTCN--------------------- ---GARGARTCNCCNGTNGTNGARTCNGTNACNATHGARACNCCNGTNGARGARGCN--- ---------------------------TCNCARAARATHAGYGARAGYGARGCNCARGGN GCNACNATGCCNAGYTCNTTYGARAARCARAAYGGNGARYTNATHTCNTCNGARGTNCAR ACNAGYGTN------YTNGAYAAYCARGGNGTNCCNGARGARGAYCCNAGYAARGAYGAY GAY------GARYTNGTNCARGARAAYGGNCCNTCNGAYGAY---------GAYGTNGAR GTNTCNAAR---------GCNGARCAYTTYGCNCARYTNAARAAR---AGYGGNGGNAAR YTNGTNTAYGAYMGNGCNTAYYTNATGGARYTNMGNGARTGYGTNTCNTCNCARACNAAR CCNGAYGGNYTNCCNCCNYTNGARATHATHYTNGAYCARCCNACNCCNTTYYTNAGYMGN CCNTCN---GGNGGNCCNGCNGAYTTYACNCCNGCNTTYTTYCARTCNGGN---GGNAAY CARMGNCAYGCNCCNCCNATHGGNAARAGYAGYAGYMGNGGNMGNCARMGNCCNGGNGAY ATGCCNGGNACNCCNMGNATHATHAARAGYYTNTCNATGTCNACNGAYGTNAAR---YTN MGNCARAGYGARAAYCCNTGGAAR------------GCNAARAARGAYGARAAYYTNGAR CCNAARACNYTNGARTCNGARATHYTNTTYATHATGAAYMGNYTNACNCCNACNAAYTTY GARAARYTNGCNGGNGARATGAARAGYYTNAARATHAARACNTAYGAYGAYYTNAARCAY YTNGTNAAYATHTTYTTYGAYAARGTNACNATHGARACNAARTTYGTNGARGCNTAYGCN YTNYTNTGYAARGTNATGTCNGGNYTNAARGTNCCNCCNCCNACNGAYGGNACNGTNAAR GAYAAYATGGCNACNTTYMGNGTNGTNATGYTNACNAARTGYCARCARGARTTYGARGCN GAYAARTCNGTNGTNTTYGARTCNCCNGARGARAARAARAARAARATGGARGCNGARAAY CCNGARAGYACNCCNGARMGNGAYGTNYTNATHGARAARACNYTNTAYCAYATGAARYTN AARMGNATGAARTTYTAYGGNAAYATHMGNTTYATHGGNGARYTNTTYAARYTNGGNATG YTNACNGARAAYATHATGCAYGAYTGYATHTTYMGNYTNYTNAARGCNMGNGAYGAYGAY TCNYTNGTNTCNYTNTGYAAYYTNYTNACNACNGTNGGNMGNYTNYTNGAYACNGAYAAR GCNAARCCNMGNATGGAYCARTAYTTYTCNCARATGTCNAARATHGCNGAYGARMGNAAR TCNMGNATHAARTTYACNYTNMGNGAYGTNATHGAYYTNMGNYTNCAYCAYTGGGTNCCN MGNAARGARGCNACNGGNCCNAARAARATHAAYGARGTNCAYAARGAYTAYGCNCARGAR CARGCNMGNAAYCARTAYYTNGCNTCNCARCCNCCNCCNCCNMGNAAYGAYAAYGTNCAR GCNGGNAAYMGNAARGGNAGYMGNCARMGNCARGARGARAAYMGNACNAGYGARGAYGGN TGGAAYACNGTNAGYTCN---AAYAARATGMGNATGATHGAYGCNAAYAARATGAARATH TCNAAR---AGYGTNGTNGAYGAYAAYATHCARYTNGGNCCNGGNGGNGGN---TCNCAY MGNCCNATGTGGAGYMGNGGNAGYCAYGGNGGNGCNCAR------CCNCARGAYGAYMGN CCNACNYTNGCNCCNAAYMGNTTYTCNGCNYTNACNAAYGAYGAYGTNMGNAARCCNTAY CCNMGNTCNCCNTCNMGNGGNGARGGNTCNGCNGGNMGNGGNCAYMGNCARGGNCARACN GCNGGNCAYGGNMGNGGNAARYTNATGACNMGNCCNAGYCARGARGGNGAYMGNMGNGAY GCNATHGCNAAYACNMGNTCNTTYATGGGNGGNMGNTCNCARAAYTCNAGYMGNGAYAAY AGYTGGAAYMGNGAYGAYMGNMGNCARTTYATGGGNCCNMGNAGYTCNTAYGARMGNGAY AAYCCNATGACNMGNAGYGAYAGYGCNGTNAAR---------GARTTYAARACNCCNGCN CCNCCN------GCNGTNAARCARATGAGYGARGAYGAYATHTCNAARAARTCNACNAAY ATHYTNGAYGARTAYYTNAAYATHMGNGAYYTNGARGARGCNMGNYTNTGYGTNAARGAR YTNAARGGNCARAAYCARATHCAYYTNTTYATHACNTCNTGYATHAAYCAYGTNYTNGAR AARAARAAYGARCARMGNGAYATGGCNGGNAAYYTNTTYCAYGARYTNGTNAGYGCNAGY ATHYTNAAYGTNAGYGCNTAYATHAARGGNYTNAAYGARGTNYTNCARTTYGCNAGYGAY ATGGTNGTNGAYATHCCNACNYTNTGGGCNTGYYTNGCNCARGTNATHAGYCCNYTNYTN GCNGGNGGNTCNYTNACNTGGCCNATGYTNAARGARGCNATGAGYCCNCAYYTNGAYAAY MGNGAYGGNGCNAARYTNATGGCNTAYGTNYTNTCNCARTGYGCNGARAARCARGGNGAR AARGARGTNTCNCARAARTGGCARAGYAGYGGNYTNAGYTGGTCNATGTAYYTNAARGAR GAYGARGTNGARTCNTTYGTNAARGARAARAAYYTNGAYTAY------------------ ---------------------ACNYTNAGYGGNGGNTCNGGNTCNACNAAYCCNYTNTCN GARYTNGARAGYATGATHMGNAAYMGNACNTCNAAYAGYYTNATHTCNACNTAYATHGAR AARTCNAGYCCNAAYAAR---TCNGAYGCNAGYTTYATHMGNGCNYTNACNACNTCNATH GTNTCNTCNTCNTTYACNGAR------------AARMGNTAYAGYGCNGAYGTNGTNATG AGYCAYAARGAYATHYTNAARMGNTAYATH---GGNAAYGAY---YTNGGNCARYTNCAR GCNYTNTAYGCNATHCARACNYTNATGGCNAARYTNGARCAYCCNTCNGGNGTNYTNTCN AARYTNTTYCARYTNTTYTAYGAYGARAAYATHGTNGARGARGAYGTNTTYTAYAARTGG GARAARTGYACNGAYCCNCARGARCARGARGCNAARGGNACNTGYATHATGCARACNMGN CARTTYTTYGTNTGGYTNMGNGARAAYGARGAYCCNGARACNGARTCNGGNTTYGCNGGN GAYAAYYTNGAYGTNACNAGYTTYGAYYTNAGYGCNTCNGCNGCNTCNYTNGGNGCNTTY GAYYTNAAYACNTCNTTYGGNCCNCCNGGN---------TCNACNGAYGAYTGGATGGAY GARYTNGAYAAYYTNGGNGAYCCNYTNGGNGAYGAYAGYATGGARGCNTTYGTNAAYYTN GARCARTAYYTNAAYGGNAAYTCNYTNTTYGAYGARGARGGNAAYYTNAAYYTNYTN--- AAYGGNGARACNGCNCARGTNGCNCCNGTNATHGAYTTYGGNYTNACNACNCARGARGCN GTNGAYATGCARGAYTTYYTNYTNCCNCCNGARGARCARATHATHGTNCARAARCCNCAR AARGCNTCNMGNAARMGNTCNGCN---------GCNTCNGCNGTNAARACNAGYYTNTAY GARATHCCNGCNCCN---------------GTNGTNGCNACNACNACN------ACNTAY ACNACNACNYTNGAYCARGTNGAYCAYGAYTAYAGYTCNAARMGNCARMGNATGTCNACN CCNTCNGARATHAAYACNCCNTCNACNAGYGGNACNGTNACNAAYAARAARGCNGCNMGN TCNAAYYTNAARYTNACNGCNGCNATHCCNAARACNGTNYTNACNCCNGCNGARGAYGAY CAYGAYGTNGTNTTYYTNGAYGAYAGYATGGAYAARCARACNGTNMGNMGNATHAARAAY AAYTAYGCNTCNAARMGNTCNMGNGARCARMGNAARCARAARYTNAGYGGNATGGAYATH GARGCNGARGCNYTNGARGTNMGNAAYAAYGARYTNMGNGARAARATHGTNGARYTNGAR AARYTNGCNAARGARATGAARGCNGCNYTNGTNGCNAARATGACNGGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYAAYGCNGCNGAYTCNACNAARGGNGARGAYGAYAGYMGNGAY GCNCCNGAYTCNAARGTNTCNTCNTCNTTYGGNGCNCARAGYMGNAARTAYTCN------ ---------------GAYTCNCARGAYGGNAAYCARGARGTNAGY---AGYTCNGAYYTN ACNGARGTNGGNTGYYTNGCNCARGCNCCNAARGTNCCNAAYTCNAGYCCNTTYGGNAAY GCNTTY------TAYGGNAAYTCNCAYAAYGCNGGNATGTAYTCNAAYCCNTTYATHCCN MGNGCNCCNYTNAARTCNGAYGTNGTNTCNACNGAYCARTCNAAYGGNAAYGAYGGNMGN GARAGYYTNATHGCNCCNAGYMGNYTNAAYGCNGCNGTNAAYMGNGARTCNTCNGARGCN GARGGNGAYAAR------TCNTTYCCNAARCARTCNATGYTNGCNCCNCCNAARYTNTCN AGYGCNGTNTTYGGNAGYGGNAGY------AGYGAYGCNCCNAGYTCNACNTTYAAYTCN TTYAAYTCNTAY---ATHMGNCCNTCNGTNTTYTCNGGNGGNTTYGAYTCNGGNATHAGY MGNGGN---GCNCCNYTNYTNAARCCNGCNAARYTNCCNGAYCCNACNAARTCNTGYGAY GGNAARGTNGAYTCNGCNAGYGARTCNGAYGTN---GTN---------ACNACNMGNAAY AGYGARGCNTCNCCNGCNAAYGAYMGNYTNAGYGGNGCNGARGTNACNGCNGGNMGNAGY GARGTNTCNTCNTCNTCNGCNTCNTCNGCNCCNTCNCARCCNGTNCCNCCNCCNGARGCN GAR---GARGGNGCNACNGCNGGNGGNGCNACNCCNTAYAAYAARGAYATHGTNCCNGAY ATHAAYAARAAYAAYMGNYTNAARGARACNTCNGGNGTNACNAGYAGYACNCARTCNTTY GTNTTYGGNAGYAAYYTNTCNCARMGNGTNAARGGNTTYTCNTCN---TCNGCNGCNGAR AAYGARGCNGCNCCNGCNTCNGGNTTYGTNTTYGGNCARTCNYTNGCNTCNMGNGCNGTN ATHGARACNAAYGGNTCNGCNCARCAYAARGAY---GARGARAGYGAYTCNGAYTCNGGN AAYAARYTNAAYCARACNYTNGARGARTCNGCNAARGARTAYCARGCNAARCAYGAYAAY AARACNGARYTNCARGTNGTNGARACNATHACNGGNGARGARGARGARTCNAAYGTNYTN CARGCNAAYGCNAARYTNTTYTTYTTYGARACNAGYAAYGAYACNTGGATHGARMGNGGN MGNGGNACNATHMGNYTNAAYGAYATGTCNGCNAARGAYAAYACNAAYTTYCARTCNMGN YTNGTNATGMGNACNCARGGNAGYYTNMGNGTNGTNYTNAAYACNAARATHTGGCCNGGN ATGTCNYTNGARMGNGCNTCNCCNAARTCNATHMGNATHACNGCNATGGAYACNGAYGAR ACNATHMGNATHTTYYTNATHACNACNAAYYTNAARGAYTCNGARAAYYTNYTNMGNGCN ATHGAYTGGMGNATHCARCARYTNAARATHCARGARGARCCNTCNMGNCARTCNTCNGAY AGYMGNACNGGNGAYAARMGNAARGCNGAYGAYTCNGAYTTYGARYTNCCNCAYAARAGY AARAARGTNAAYAGYTCNCCNGAYCARAGYATHTCNATHAGYAARAARGARGARTCNGAY AGYAGYGTNCARGAYCCNGARACNGARGCNTCNTGYGARAGYCAYTCNTCNTCNYTNACN ATHAARTCNGARTCNGAYTTYCAYTGYATHCAYTGYGGNAGYTCNGTNAAYAARYTNTAY CAYGAYTAYAARGTNGGNATHATHAARYTNACNAAYTGYAARGCNTGYGGNAAYGTNGTN GAYAARTAYGTNGARTAYGAYCCNTGYATHATHYTNYTNGAYGTNYTNYTNATGCAYAAR CCNGCNTAYGCNCAYYTNYTNYTNAAYTCNCAYGTNAARTCNYTNYTNAARGCNGCNGTN YTNYTNYTNGTNATHCARTCNTTYGTNAARYTNATHCARCARMGNTCNGAR--------- ------CAYAAYGCNACNGAYATHGARAAYTAYTAYTTYGTNGGNYTNGAYYTNTAYTTY AAYTCNATGATGGCNGCNGTNGARYTNACNAGYTTYYTNTCNACNATHYTNGGNGTNYTN ATGATHTGGTGYYTNGTNTCNACNMGNAGYYTNCARTCNYTNAARCCNATHTAYATHACN AARGCNGTNYTNYTNTGYAAYYTNGGNTCNGTNYTNGCNATGCCNGCNYTNYTNTGGGGN AARTCNTTYAGYCCNGTNTTYGTNTGGYTNGGNGARGTNTTYATHTGYATHTCNGCNYTN CARGCNYTNMGNGTNGTNYTNCARGTNCCN---CAYAARACNYTNTTYGCNGTNGTNGCN GTNGCNTGYGGNATHGTNGTNAARACNGTNATGGCNGAYGCNATHAARGAYYTNTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGCNTCNAAY ---GTNTCNMGNACNTTYGTNAARTCNYTNAARGGNMGNACNTTYGCNGCNGCNGCNGCN GCNCARGCNGARAARGTNAAYGCNGCN------------AGYTGYTCNATHAARAARYTN AAYAAYGGNGTNCAYGTNGGNGTNATHAAYTCNAAYTCNCCNATHGCNMGNGTNGCNGTN GTNGCNCARGCNGGNTCNMGNTTYGARAAYGGNGAYAAYYTNGGNGTNTCNCAYTTYYTN MGNATGTCNACNMGNYTNMGNACNCARAAYATGACNAGYYTNGGNATGACNMGNACNGTN CARCARYTNGGNGCNGAYGTNACNATHACNGGNACNMGNGARTAYATHTAYTTYAARAGY GCNGTNACNMGNAAYTGYYTNAAYGAYGTNGTNGCNGTNYTNCARGAYYTNACNACNAAR CARGCNTAYCARCCNTGGGARATGACNGAYGTNCARAARGAYCARAAYGGNATGGGNYTN GAYYTNGCNYTNYTNAAYAAYMGNCCNCAYGTNTGYGCNYTNGARYTNYTNCAYTCNGCN GCNTTYMGNAAYACNYTNGGNAAYTCNYTNTAYGCNCCNGARCAYGCNATHGGNAGYTTY ACNCCNGAYCARGTNYTNCARTAYGTNAARAAYTAYTTYAGYATHGGNMGNYTNGCNYTN GTNGGNATHGGNGTNGAYGARGCNGARYTNCARGAYYTNGCNTCNTCNTTYGARCCNTAY GCNTCNGCNGGNGTNCCNGCNGARAARGCNACNTAYCAY---GGNGGNGARGTNMGNAAR AAYATHGGNGGNGGNYTNGCNCAYGTNGCNGTNGGNTTYGARGGNCCNAGYYTNACNAGY AARAAYYTNYTNGCNGTNGARGTNYTNMGNCAYATHYTNGGNTCNGGNCCNCAYATHAAR TAYAGYAGYGGNACNTCNGCNGCNYTNYTNGCNAARACNGCNGCNGGNGCNACNGAYGCN CCNTTYCAYGTNTCNGCNYTNAAYGCNACNTAYTCNGAYAAYGGNYTNTTYGGNTTYACN GCNGTNGCNCAYGCNTCNCARATHGAYAARGTNGTNCARGCNGCNGCNAAYCARTTYAAR AAY---YTNACNTCNGGNATHACNGAYAARGAYATHGCNMGNGGNAARAAYCARYTNAAR GCNGARATHTGYATGCAYTTYGARAAYCCNGAYGTNYTNYTNAAYTGGYTNGGNGARCAR GCNTTYAGYGGNCARGAYGTNGTNACNCCNGARGAYATHTAYAARATGGTNGAYGGNGTN AAYGCNAGYGARGTNAARAAYGCNGCNAGYAAYGTNYTNAARTCNMGNCCNAGYATGGGN TCNATHGGNAAYACNGCNAAYGTNCCNTAYYTNGAYAARYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNTCNTGGTTYAARCARCAR YTNAARTCNTGGYTNMGNATHTCNGTNTCNGARMGNYTNYTNTAYYTNTGYGGNACNAAY TTYTTYYTNATGYTNYTNATHTTYGGNTGGCAYMGNATHCCNAAYGTNTAYYTNTGGGAY ATHGAYGTNGARAARMGNTGGYTNTTYTCNTCNTTYYTNTTYYTNTTYCAYATHGGNTGY TGGATHGTNATGGGNYTNGARYTNATGYTNATGGAYGTNGGNGAYTTYTCNGGNATHACN CARGTNTAYAAYTAYCAYAAYGGNATHAARCCNGTN---YTNACNAAYAARTCNAGYMGN YTNCARGARYTNTTYTCNMGNATGMGNCAYCCNGGNCCNGTNYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGGMGNCCN AAYGARGTNGCNCARTGGTCNGAYGCNGTNGGNYTNGGNGARAARMGNTCNYTNTTYYTN GAYCAYAAYGTNGAYGGNATHCARYTNYTNACNACNGAYGGNYTNCAYYTNCARMGNYTN GGNGTNAARACNGCNCARGARGCNGTNMGNATHGARAGYCAYATHMGNGARYTNAAYTAY GCNAARMGNCARTGYGTNGGNAAYATHGARACNYTNCCNTAYTTYTAYTAYMGNGCNYTN AAYAARGGNYTNGCNCCNCCNCCNMGNTAYTAYGGNGARYTNYTNCAYTAYAGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATGGCNAGYGAYCAYGAYYTNATHGCNYTNTAYCARCCNCCNCAYGAYTGYAAY GGNGAYMGNTGYGARCCNTGGYTNCCNCCNTTYYTNTAYTGYGTNGTNGCNCCNGCNACN GTN---GTNTTYATHYTNATHATHGTNGCNGTNGTNTGGTGYTGYAAR---AARCCNTGG AARTGYAARAARTAYTCNTCNYTNGCNGGNGAYAAYAGYGAYATHCARATGGARGAYTAY AAYACNATHMGNMGNGCNTCNYTNTGYYTNMGNCARATGTCNCAYAAYMGNGARACNCCN ATHATGGGNAGYMGNGCNGGN---TCNATGACNYTNGAYMGNTCNTAYMGNCARAAYMGN MGNGGNMGNGAYTAYTGYAAYTCNGCNCCNGGNACNYTNCARMGNCARAAYMGNMGNCAR TCNACNGTNGARGAYGARMGNCCNTCNCCNCCNACNGGNCARMGN--------------- ------------CCNCAYCCNCCNCCNTAYTCNATGYTNCCNAAYACNYTNGCNTTYMGN TCNGAYAAYATHCCNTCN---GGNGCNCARACNAGYTTYAAYGAYGAYAAYGAYCAYGAY CAYAGYGGNGGNGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TAYMGNCARTAYYTNGGNTTY YTNYTNCARYTNYTNAARATGGAYGTNAAYATHGTNATHTTYATHGARCCNAARGGNGTN GAYTTYGTNATGMGNTCNMGNATGGARMGNGARACNMGNACNMGNATHATHCCNACNAAR GTNGARGAYYTNGARTAYCAYTCNYTNYTNCCNMGNATHMGNCARATHATGGAYAGYCAR GARTTYAARACNAAYAAYACNAAYTAYGARAARGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNMGNGGNGCNCCNTAYGGNGAYGTNTTYMGNTGGTTYATGGAR AAYGTNGCNTAYGAYGTNTAYGGNGTNTTYTTYTGYCAYGGNYTNGGNGGNAAYCARYTN TTYMGNYTNAAYGCNAARGGNCARYTNGGNYTNGGNGARMGNTGYATHYTNGAYGARCAR GARGAYACNYTNCAYATHCAYGTNTGYTCNATHCARCCNGAYGGNCCNTGG--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------TGGAARGAYAARTGYGTNAARYTNGARAARGTNATHAARACN YTNTCNAAYCAYTGYGTNMGNGTNGTNGARCARCAYGARGAYYTNYTNTCNAARTTYAAY AARAAYCARGARCARTTYAAYYTNATGAARGCNAARTAYCAYGARMGNGGNGARCARATH AARAARGCNMGNGARGTNYTNGTNCCNATHTCNAAYGARYTNAARACNYTNMGNGARAAR TAYGARATHGCNGTNCAYTGYCARGTNCARGCNGARACNTTYGCNATHGARACNACNAAR ACNAAYAARAARATGGTNMGNCARAGYCARATGYTNMGNGCNAAYYTNAARGCNAAYCAR YTNGTNGAYATHAAYGTNGAYGAYGAYAAYYTNGGNGAYGARGARGARCARAARTAYATH GARAARYTNGGNCARCARATHGAYGARYTNGARGARGARAARACNGCNYTNAGYGTNAAR ATGAARATGATGAGYAAYAAYYTNYTNGARGARAARGARACNAAYGARCAYYTNAARGAR AARATHGCNYTNATGAARGGNGARYTNYTNCARTCNAARCARGCNGTNAARCARCARGAR GARATHYTNCARCARGTNGCNGARAARTCNGARAARGCNTTYTTYGARTTYCARGAYATG GARCARACNTAYAARAARGARATGATGGTNMGNGGNGARGCNGARMGNGTNGCNCAYMGN YTNCAYGCNGARMGNGAYCARGCNMGNMGNGARAGYACNATGGCNYTNAGYAARATHGCN GAYAAYAARAARYTNATGGARGCNATGYTNGARATHCARGAYYTNAAYACNCARTCNGTN CARATGAARGARGARTAYGARAARCARATHTCNGARYTNAARGARCARGTNAAYGCNGCN AARGARGTNTAYGAYTCNGARGCNGTNGGNGARGARAAYGAYGARYTNGARGCNGARAAR AARGARYTNCARGCNAARYTNGARAARACNGARGGNGAYGTNAARCARYTNAAYACNAAR TAYACNCARYTNYTNGARACNTAYAARAARYTNGARGCNAARTAYAARGARGCNACNACN GCNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNACNAARAARTCNGARGGN TTYYTNTCNMGNATHGTNGGNMGNAARGCNCARMGNGARAARGCNAARGARAARYTNAAR AARGGNGGNGTNACNGTNAAYGCNGGNCAYTCNAARGCNGTNGARGARATGATGAARMGN ATHCARAGYGGNAAYATHGGNYTNAARCCNGTNTCNATGMGNMGNACN---------CAY TCNYTNCCNGARMGNGARGARCCNAGYGCNATHTCNGARYTNCARGGNYTNYTNAAYAAR ATGMGNAARTCNCAYAGYGARGAYGAYYTNTCNGTNTTY---GGNGAYTCNGGNYTNGAY GARAAYTCNGARYTNGGNAARATHTTYAARAAR---MGNCARCARATHGTNCARACNACN GARATHGCNACNGARACNGARAAY------------------GCN--------------- ------MGNCCNGTNCCNYTNCCNMGNAARYTNTCNACNATHCARGAYGARGCNGAYGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CAYATHATGGGNTCNTCNTCNGAYCCNATHYTNAAYYTN ATHCARCARAAYCCNTCNYTNGGNATGAARTCNTTYTCNCCNACNGGNCCNCCNCCNACN ATGYTNACNTCNYTNCCNCCNMGNYTNCCNAAYAAYGCNMGNAAYGTNTCNCCNYTNATG TTYAGYCARCARCCNCCNYTNCAYYTNAAYGCNCCNTCNCCNATHCAYCCNTCNCARYTN TCNCCNTCNTCNYTNACNMGNTCNCCNGTNYTNCARMGNGGNTAYAGYCCNCARGARTTY GCN------------GCNGTNATGCARAAYGCNATHTAYAARAARCARCARCARAAYCAR AGYGAYCAYTTYAAYAARAARCCNGARAGYMGNCCNAAYTCNCCNAGYGTNCARYTNAAR GTNGTNAARCCNCARCCNGCNGCNCARTCNATHYTNCCNCCNACNCCNCARCCNAARGGN GCNACNGTNAAYACNTTYACNCCNACNTCNGTNYTNGTNAARATGCAYTCNGAYAARGCN ATGGARAARGARAARCARGTNCARGGNYTNGGNGAYCAYAARGTNGTNGAYTAYATGCCN TCNATGGARGARYTNAGYAAYGGNGGNGGNGAYCAYGAYCARCAYACNGGNATHGTNGGN MGNCCNTCNCCNCCNCCNGAYGTNAAYGAYATHAGYTTYYTNGARCCNATHAAYCCNAAY GTNATHGCNYTNTCNAAYCARATHGAYGGNAGYYTNMGNATHAAYATHYTNCCNGGNAGY YTNTCNCARCCNATGTCNGTNGARGARAARCCNGGNATGGGNTCNYTNTCNCCNGCNGCN YTNACNGCNACNATHCARCAYGTNTCNTCNAARATGAAYGGNCCNATGGTNCCNCCNGCN GGNAAYGTNAAYGGNGGNGGNCCNGGNATGAAYGTNGGNATHCARMGNTGGTTYMGNCCN GAYATHYTNAARACNCARTTYCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AARATGAARMGN TCNGARMGNCAYATGATGMGNYTNAARAGYATHATHAARAAYGCNYTNTCNGARAARGGN GTNAARGARAGYGAYTCNATHCAYCARGCNTGYGCNAAYAAYYTNYTNAAYGTNAGYATH ATHYTNYTNAARACNYTNCCNAAYTCNCARAAYYTNACNGCNGARATGAARTCNGTNGTN TAYGGNCARGTNCARCARATHATHAAYYTNGARAARMGNMGNTCNGGNATHTCNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARGTNTCNTTYGTNYTNGAYAAYTCNGCN TTYGARTTYATHGCNGAYYTNTGYTTYGCNGARTAYYTNYTNTCNTCNGGNYTNGCNTCN CAYATHCAYTTYCAYGGNAARGCNATGCCNTGGTTYGTNTCNGAYGTNACNACNGGNGAY GTNTCNTGGACNYTNCARCARYTNGCNGGNATGAAYGAYGARGCNGTNAAYCAYYTNTGY GARACNTGGCARAARMGNYTNMGNAAYGGNACNATGACNTTYCARTAYCAYCCNTTYTGG ACNATGTCNTAYTCNTTYTCNGARATGGARTCNYTNTGYCCNGARYTNTAYTCNATGYTN AGYGARACNGARATHGTNATHTTYAARGGNGAYYTNAAYTAYMGNAARYTNGTNGGNGAY YTNAARTGGGARACNACNACNAGYTTYACNACNAGYYTNMGNGGNTTYAGYCCNACNTCN GTNTGYGCNYTNMGNACNYTNAARGCNGAYGTNATHGTNGGNYTNAARCCNGGNCARGCN GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TAYMGNAARAARMGNAGYMGNAGY MGNAGYMGNGAYAARGARMGNMGNMGNTCNMGNAGYMGNGARMGNMGN------------ ---------------------------------------MGNGAYGGNMGNAARMGNAGY MGNAGYMGNGARMGNMGNMGN---MGNAGYAARAGYMGNGAYMGNMGNMGN--------- MGNAGYMGNAGYAARGARAARMGNMGNTAYAGYMGNAGYCCNATHMGN------------ ---------------GARMGNYTNCCNGARATGACNGTNGARGARMGNGAYGTNMGNACN ATHTTYTGYATGCARYTNTCNGCNMGNATHMGNCCNMGNGAYYTNGARGARTTYTTYTCN TCNGTNGGNAARGTNMGNGAYGTNMGNYTNATHACNGAYAAYAARACNMGNMGNTCNAAR GGNATHGCNTAYGTNGARTTYGCNGAYCCNGARTCNGTNACNYTNGCNATGGGNYTNACN GGNCARAARYTNYTNGGNGTNCCNATHYTNGTNCARCCNTCNCARGCNGARAARAAYMGN TCNCARCCNGCNGTN---GCNCCNGCNATGAARTCN---GCNCCNGARGGNCCNYTNMGN YTNTAYGTNGGNTCNYTNCAYTTYAAYATHAAYGARGAYATGYTNMGNGGNATHTTYGAR CCNTTYGGNAARATHGTNGAYATHAARATHATGAARGAYCAYGARACNTCNMGNTCNYTN GGNTTYGGNTTYATHAGYTTYGCNAAYGCNGAYGAYGCNAARAARGCNYTNGAYCARYTN AAYGGNTTYGARYTNGCNGGNMGNCCNATGAARGTNGGNAAYGTNACNGARMGNGGNGCN GGNGAYGGNACNCAR------AAY------GGNGTNGGNGGNCAYYTNGAYACNGAYGAR ATGGAYMGNGCNGGNATHGAYYTNGGNGCNACNGGNMGNYTNCARYTNATGGCNAARYTN GCNGARGGNACNGGNTTYCARATHCCNCARTAYGCNGCNAAYGCNYTNAAYAAYCCNGCN CCNGCNGCNGCNCCNACNGGNGCNGCNGGNYTNCCNCCNAAYATHCCNYTNCCN------ ---GGNGCNACNATHCCNACNCCNGCNCCNCCNCCNCCNCARCCNCCN------------ ---------ACNGTNGCNCCNCCNATHGCNACNCARTGYTTYATGYTNTCNAAYATGTTY GARCCNACNACNGARAGYMGNYTNACNTGGGAYCARGARGTNMGNGAYGAYGTNATHGAY GARTGYAAYAARCAYGGNGGNGTNYTNCAYATHTAYGTNGAYAARAAYTCNCCNCARGGN AAYGTNTAYGTNAARTGYCCNACNATHTCNGCNGCNGTNGCNTCNGTNAAYTCNYTNCAY GGNMGNTTYTTYGCNGGNMGNGTNATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNTTYYTNGAYAARTTYCARAARAGY CARAAYTAYCARTCNAARYTNTTYAAYMGNATHTCNCAYAAYTAYGTNAARYTNATGATG TCNMGNGTNGAYCCNACNGCNAARGAYACNTTYTTYAARGAYTTYCCNAARYTNATGTCN CARTCNATHTAYGCNTCNTTYTGYTTYTGYTTYCCNGAYTCNTAYMGNCARTTYGGNGAR CCNTTYAARGAYGARYTNACNTAYYTNGTNTAYGGNTGGATGGCNGGNATHMGNCCNGCN CCNMGNAAYTGGATGACNTGGGAYATGTCNCAYYTNGARCCNCCNAAYYTNAARATGMGN GARGAYYTNATGCARAARAARAAYAGYAARAARATGACNTCNYTNATHGAYTTYGAYTAY YTNGAYTCNYTNATHTCNACNAAYGCNAGYCARTAYGCNTCNACNATGTCNYTNGCNCAR TCNACNTCNAARGGNTCNACNGGNTCNAAYGTNACN---GCN---MGNAARCCNMGNATG CAYGCNMGNATHAGYAAR---ACNCARAARCCNTTYTTYMGNACNTCNTCNCCNAAYAAR TCNCARTCNCCN------TCNCARGAYACNAAYYTNATHGAYGCNGTNGCNGAYGCNCAR AAYAGYCCNGGNGCNMGNGCNAARGARAARMGN--------------------------- GCNAARGAYGGNAARMGNCARAGYGARGCNYTNACNCCNATHMGNGARATGGCNAGYGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNAAYAARACNTCNGTN MGNCCNGGNYTNAARAAYTGYGGNGAYGTNAAYTGYATHGGNMGNATHCAYGCNTAYYTN GARGCNGTNGGNGCNATHAAYTTYGGNTGYGARCARGCNTCNTAYAAYAAYCCNCARMGN AGYTCNATHGGNGGNCCNAAYAAYAARTCNAAR---GTNNNNTTYAAYAARGARYTNGTN TCNTCNACNGCNAARTCNGAYTTYCARMGNCCNMGNAARMGNMGNATHMGNGAYGARAGY GGNATHTGGGTNGAYGARAARGARYTNGARGGNAARACNATHGARCAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNGCNGARTCN CCNMGNTAYMGNGCNCCNAAYCAYTTYGAYTAYGAYGAYYTNGARMGNAARTAYTGGAAR AAYATHACNTTYGGNCARGCNATHTAYGGNGCNGAYATHAGYGGNACNATHACNGAYGAR GAYCARGAYGTNTGGAAYATHAAYMGNYTNGGNTCNATHYTNGAYCAYATHAARAAYGAY TAYAAYATHAARATHGARGGNGTNTCNACNGCNTAYYTNTAYTTYGGNATGTGGAARACN ACNTTYGCNTGGCAYACNGARGAYATGGAYYTNTAYAGYATHAAYTAYYTNCAYTTYGGN GCNCCNAARTCNTGGTAYGCNATHCCNCCNGARCAYGGNCARMGNYTNGARMGNYTNGCN TCNGGNTTYTTYCCNAGYAGYTTYGGNGARTGYCCNGCNTTYYTNMGNCAYAARATGTCN YTNATHTCNCCNCAYATHYTNAARAARTAYTCNATHCCNGTNAAYAARGTNACNCARGAR GCNGGNGAYATHATHATHACNTTYCCNTAYGGNTAYCAYGCNGGNTAYAAYCAYGGNTTY AAYTGYGCNGARTCNACNAAYTTYGCNTCNGARMGNTGGATHGARTAYGGNAARMGNTGY YTNCARTGYGTNTGYMGNMGNGAYGGNGTNAARATHCAYATGGAYGTNTTYGTNAARMGN TAYCARCCNGARMGNTAYGAYYTNTGGAARGARGGNAARGAYATHGCNCCNCAYCCNGAR GGNCAYMGNGAYGCNAGYMGNYTNGGNGGNGGNMGNGGNCARAARAARAARATHGARGCN AAYAGYACNGGNACNGCNCAYTCNMGNMGNCAYCCNYTNAARGAYGARTTYAAYACNCCN AGYTGYAAYGGNAAYCARGCNTCNTCNTCNAAYCCNCCNAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHATHAARTGGYTNCCNCARTAYMGNGGNGAYACNTTYGTNGCNGAY YTNGTNGCNGGNGTNACNGTNGGNYTNACNGTNATHCCNCARGGNYTNGCNTAYGCNTCN ATHGCNAAYYTNCCNCCNCARTAYGGNYTNTAYTCNGCNTTYATGGGNTGYTTYGTNTAY TGYYTNATGGGNACNTCNAARGAYATHACNYTNGGNCCNACNGCNATHATGTCNYTNATG ACNGCNACNTTYGGN------TCNCCNGTNTCNGGNGAYGTNACNATHGCNATHYTNYTN ACNYTNATHTCNGGNGTNGTNCARYTNYTNATGGGNYTNYTNCARYTNGGNATHYTNGTN AGYTAYATHTCNTAYCCNGTNATHAAYGCNTTYACNTCNGCNGCNGCNATHACNATHGCN TTYGGNCARGTNAARAAYATHYTNGGNYTNAARGAYATHGAYMGNGARTTYYTNCAYATG GTNTAYGARACNTTYGARAARATHCCNGARACN------------GARYTNCARYTNYTN YTNAGYYTNCAYAARGCNYTNGTNYTNGAYGAYCARACNCARAARGTNAARTGYAGYYTN ACNAAYCAYGARATGCCNGCNAARGCNTCNGCNATHGARAGYTAYATHAARGGNAARAAR TAYAARMGNYTNGCNGAYYTNAAYGCNYTNTCNTAYGAYGAYCAYAARCARCAYATHCAR CCN------AAYAARAARMGNGARAARGARATGTTYTGYMGNYTNACNYTNMGNCAYATH GARAARACNGGNCCNGCNATHMGNMGNCAYATHGGNGGNAARAARTAYAARAAYGCNYTN GCNMGNTGGAAYGARTGYCARMGNACNGGNAARAARTTYGTNGCNAGYGCNAARMGNTCN AAYGTNACNGAYGGNAAYGAYGAYTCNACNAGYATHGARAGYGGNGAYGAYTTYATGGAY GAYGAYGAYACN---AARGARGARYTNGAYGAYATGAGYGAYYTNTAYCCNGCNGCNGAY TTYGARGARGAYGAYTCNGGNGAY---------GAYGARGARCARGGNGAYGAYGAYGCN GAYAARCAYTCNGGNGAYGARATGGARGAYGARGARGARGARGARAAYTCNCCNCCNAAR AARTCNAARAAYAARACNGARAARAAYAGYAARCARAAYAARAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CCNACNATGYTNGTNCAYGGNGCNGAYAAYYTNGARGAR YTNACNAGYMGNGARYTNAAYTGYYTNGAYATGTGYYTNCCNTCNGGNTCNCARATGATH ATGGGNCCNAAYGGNYTNGCNGTNGTNGTNGGNGAYAAYCAYCCNAARYTNAARAARGAY GTNTCNGARATGTTYTCNGAYGARMGNATHGCNGARTAYYTNCCNATHATHMGNAARCAY ATHMGNGCNCAYATHGARAARTGGYTNCARGARGGNGAYAAYGGNAARGARGTNATHTCN TTYAAYGTNTGYCARGAYTCNATHTAYGAYATHTAYYTNGARYTNGCNTTYGGNTGYMGN ACNGAYGAYCCNAARTAYGAYGTNATGAARCARGCNATHMGNGAYGCNGGNGCNGTNYTN ACNTCNATHCCNACNACNGAYCCNGAYAGYGAYTTYCARAARGGNATGGCNGGNMGNMGN ATHYTNGAYGARTAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATHYTNTCNTGYTTYMGNACNYTNCAYMGNGCNMGNMGN GARGTNTTYGCNGGNGAYGARAARGCNYTNTAYGARGTNMGNGAYAARATHAAYACNGAR TTYMGNGARAARYTNGGNGARACNGAYGCNGCNAARATHGARGARAAYTTYATHACNGCN AARGAYGTNGCNTAYYTNYTNMGNTCNACNGTNGTNCARYTNAARCARAAR------GAY GARGAYACNTAYGARYTNMGNATHACNAARAAYACNCAYYTNCCNAAYAAYACNGCNTAY GAYCCNACNAARGARATGYTNGTNCARCCNMGNAARMGNAARGGNTCN------------ ------AAYTCNMGNTTYYTNGTNMGNGCNAARGARATGAARGARTTYTTYAARYTNACN GARGAYTCNGTNATHCAYGAYTTYYTNAARATGGAYAGYTGYAARMGNATHGCNGAYAAR TAYYTNYTNGCNATGGTNTTYGCNTAYTTYAARMGNGCNGAYTTYACNYTNAARGAYTAY ACNMGNATGAAYTTYTTYATHGCNYTNTAYYTNGCNAAYGAYGTNGARGARGARGARGAR GARYTNAARTAYGARATHYTNCCNTGGGCNYTNGGNAARGARTGGMGNGARACNTAYATG GAYTTYATHAARGARMGNGAYYTNYTNTTYAARCARATHGAYTAYAARGCNATHATHAGY MGNAARTGYTGYGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNATH AARAAYAGYMGNTCNYTNCCNGTNATHCARAAYYTNATHMGNGCNAGYTGYGTNGGNCCN YTNGTNACNATGGCNYTNAGYGARCAYCAYGTNATGCARAAYGARGCNYTNYTNGCNYTN ACNGCNATHTGYAGYACNGCNCCNGGNGAYGCNGCNGTNTCNYTNAARGARGCNGAYYTN CCNACNGCNATHACNAARYTNYTNCARGAYGAYAAYYTNCCNCCNGARYTNACNGAYAGY CAYMGNYTNTTYYTNCARAGYYTNATGTCNAARGGNGTNATGAGYACNTCNGARGTNAAR GCNTGYTAYATHAARTCNAARGAYMGNTTYTCNGARCCNTAYGARACNGAY--------- AAYTCNATHGTNGGN---------------TTYGTNCAYACNATHAAYGCNGCNATHTCN CCNTTYCAYYTNGARATHAARAARGGNTTYCARGARCAYAAYGGNYTNAGYGTNTAYTGY YTNGTNAAYACNGTNGARAGYCCNATHTCNMGNYTNTCNTCNACNTAYACNCCNAAYGAR YTNGARYTNTAYAARAARYTNATHGARTAYATHGTNGARTCNGAYGAYGGNAARATHGGN TCNMGNAGYGCNYTNAAYYTNACNGARAARYTNGARAARAARATGGGNAARGARGAYGCN CARAAYTTYTTYGAYAGYYTNGARAAYGARAARTGGATHGTNAARGAYGARAAYGGNAAR ATHTCNYTNTCNATHMGNTCNYTNYTNGARYTNGAYCARTAYYTNCARGAYATGTAYCCN ACNYTNATHAARAARTGYAAYATHTGYGAYAARATHTGYATGCARGGNAAYTCNTGYGGN AAYTGYGGNATHMGNATGCAYYTNAARTGYTCNAARACNTAYTTYTCNAARCARACN--- GAYMGNAARTGYCCNGTNTCNACNTGYAARGCNCCNTGGACNCARGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNAAYAARAARGTNMGNGTNTGGGGNMGNYTNMGNCCNACNGCNAAYTTYGCNTAYGAR AAYGTNGARTTYYTNCCNGAYAAYAARGGNATHAAYGTNCAYATGMGNMGNGAYCCNAAR AARGGNGTNGTNAAYAAYCARATHYTNGAYTGGTCNTTYAARYTNGAYGGNATHTTYAGY AAYGCNGAYCARGARGTNGTNTAYAAYACNGTNACNTCNGAYATHGTNTCNGGNTCNYTN GAYGGNTAYAAYGGNACNYTNATGTGYTAYGGNCARACNGGNGCNGGNAARACNTTYACN ATGACNGGNGCNACNGARAGYTAYMGNCAYMGNGGNGTNATHCCNMGNGCNATHTCNCAR YTNTTYMGNCARATHGARGAYMGNYTNGARAAYAGYATHAGYGTNMGNATHTCNTAYATG GARATHTAYAAYGARCARATGTTYGAYYTNYTNGGNAGYTTYCCNGARTCNAAYTGGGCN AAY------AARGAYATHAGYAAYCAYYTNGAYCCNATGGTNATHTCNGARAAYCARGGN GGNGTNTTYGTNAARGGNYTNTCNTGYCAYYTNGCNCARAAYGARGARGARGCNYTNAAY YTNYTNTTYGARGGNGARACNAAYMGNTCNATHGCNGCNCAYTCNYTNAAYAARCARTCN TCNMGNTCNCAYTGYATHTTYACNGTNTAYATHGARTCNMGNTCNMGNGTNCARTCNAAY GCNAARTAYACNGTNTCNAARYTNAAYTTYGTNGAYYTNGCNGGNTCNGARMGNYTNAGY AARACNAARTCNGARGGNAARACNAARGARGARGCNATGTAYATHAAYAARTCNYTNTCN TTYYTNGARCARGTNGTNGTNGCNYTNGCNTCNAARAAYMGNGAYCAYGTNCCNTTYMGN CARTCNAARYTNACNCAYTTYYTNAARGAYTCNATHGGNGGNAAYTGYAAYACNGTNYTN ATHGCNAAYATGTGGGGNGARAARCARCARYTNGARGARACNGTNTCNACNYTNMGNTTY GCNACNMGNATGATGTGYGTNGCNAGYGARCCNGCNAARAAYGARATHTAYGAYCCNGCN YTNYTNGTNAARAARYTNCARAARGARATHAGYCAYYTNAARAAYGARYTNACNATGCAY GAYACNYTNACNAAYMGNAGYATGGTNTCNTAYGAYGCNYTNTCNGARCARCARAARTAY GARATHMGNACNCARGTNCARMGNTAYYTNGARGGNAGYYTNGAYTCNATHGAYATHATH AAYATHMGNCARATHGTNGGNTGYTTYGARACNTTYMGNGARACNTAYYTNGAYATGGAR AARGARATGGARGCNAARYTNMGNGARAARTAYATGYTNATHGAYAARACNGAYCCNAAY TCNATHGCNGCNGCNCARCAR--------------------------------------- ------GCNGGNGTNCCNATHGCNGAYGAYGGNTCNTTYGTNGGNGARYTNGARGGNGGN GGNTTYGGNGTNGGNACNGCNCCNAARGTNTCNAARACNGAYAGYTCNGCNGTNGTNCAR YTNAARAARAARGARMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNTAYGGN CARTTYGARCARYTNTAYGCNAAYTAYTTYMGNTTYAAYTTYGCNACNAARATGACNAAY ATHGGNCARGARACNAGYCAYTAYACNCCNTCNTCNCAYYTNCARGAYGARAARMGNMGN GARAAYGARCARYTNAARGARAARGTNAARCARYTNGAYCARYTNAAYCARTCNAGYAAY GAYYTNGCNYTNAAYACNMGNCCNAAYMGNCARATGGARGAYCCNCARTCNGCNYTNMGN CCNTAYCCNTGYTCNGAYATGACNCARGTNGTNACNACNTTYGARTGGGTNATHACNGAY TAYTAYGARAARYTNGAYATGGARAARAGYGGNAARGTNCCNCAYACNGTNTCNGARCCN TTYTAYATHGARCARTTYGGNTAYMGNGTNTGYYTNGAYGCNTAYYTNAAYGGNGAYGGN CAR------AARMGNTGYATGTCNYTNTAYYTNMGNGTNGTNATGGGNCAYTAYGAYATG TTYYTNAARTGGCCNGTNACNTTYGGNGTNAARTTYGTNGTNGTNAAY---CCNAAYGAR AAYAGYGAYTCNYTNAGYTTYGGNAGYACNAARAARACNYTNTTYACNTAYAAYCARCCN ACNGGNATHAAYGARGAYGTNACNAAYGCNTGGGGNYTNAAYGARTTYGTNAGYCAYGAY GAYGTNMGNACNCARTCNYTNGTNAARGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARACNTTYCCNATHTTYATHGTNGAY GCNTTYACNAARGTNGCNATGAGYGGNAAYCCNGCNGCNGTNTGYYTNGTNCCNCARGAY ACNATGYTNGGNGAYGAYGARATGCARAARATHGGNGCNGARATGAAYYTNTCNGARACN GCNTTY------GTNTGYCCNMGNGAYGGNAAYTTYAARTCNGGNACNGAYTTYTCNYTN MGNTGGTTYACNCCNACNAAYGARGTNGAYYTNTGYGGNCAYGCNACNYTNGCNTCNGCN GCNGTNYTNTTYCARGAYGTNGGNAAYYTNCARGARACNATHCAYTTYCAYACNAARAGY GGNAARYTNTCNGTNACNCARAGYCCNTCNAARTCNGGNTTYYTNGCNATGGAYYTNCCN AARAAYGCNCCNYTNYTNCARGARGTNGAYCAYTTYAARCAYYTNYTNYTNAARTGYYTN GGNGAYYTNGAYYTNGTNCARGARGTNAGYTAYTCNCCNACNACNAAR---AARYTNYTN GTNMGNYTNAARGAYGAYYTNAAYMGNTCNGTNYTNGARMGNYTNCARCCNAARGGNTCN GARYTNYTNGAYGTNGAYACNCARGGNAARGTNAARGGNATHGGNYTNACNYTNAARGGN TCNAARGTNAAYGGNTGYGTNGAYCCNGARGGNAAYGTNTAYGAYTTYGTNTCNMGNTAY TTYGCNCCNTGGAAYGGNATHCCNGARGAYCCNGTNACNGGNTCNTGGCAYACNGTNGCN GGNCCNTAYTGGTGYCARCARYTNAAYAARGCNCARYTNTAYGCNMGNCARTGYTCNCCN MGNGGNGGNGAYYTNCARGTNGAYGTNAARGAYACNMGNGTNACNGTNATGGGNCARGCN GTNATHAAYYTNAARGGNGTNTTYTAYGTNATGGGNAGYAAYCCNAARAARCARTCNAAR TCNTTYAARGTNYTNCARTGGATGACNGARACNGARMGNGARGARGGNTCNGARGARGAR CCNMGNGGNAAYGCNGGN---------------CCNAARAARCAYMGNAAYCCNGAYYTN MGNCAYAAYAAYGAYGAYGAYGARATGMGNTTYACNGGNYTNCAYGAYAARTCNGAYATH CCNTCNAARGCNTTYGAYATGYTNGCNAAR---------------TCNACNCCNATHACN GARAAYGGNCARGAYAAYAAYGAYTAYGGNAAYGGNGAYGAYACNGTNGGNGAYTAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TCNAAR TTYTTYCCNCARATHAAYAARTTYATHCAYAARGCNMGNYTNGARGGNGGNGGNGTNYTN GTNCAYTGYYTNGCNGGNGTNTCNMGNAGYGTNACNGTNACNGCNGCNTAYATHATGACN GTNACNGARYTNGGNTGGMGNGAYGCNYTNAAYTCNATHMGNGGNGCNMGNAGYGTNGCN AAYCCNAAYTAYGGNTTYCARAARCARYTNCARCAYTAYGAYTCNGARCARGTNATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARTTYGGNAGYGTNGCNYTNCARGARAARYTNAAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNAARTCNGARCAYGTNGGNYTNAARGAR ATHGCNMGNGGNAARTGGATHTGYYTNAAYAAYATHACNTAYAARGAYCCNAAYGGNATH CARMGNACNTGGGARGGNGTNTCNMGNACNACNAARTGYAGYGGNGARGCNGAYGCNGTN GGNATGATHTGYATHTTYAARGAYCCNATHACNGAYYTNCARAGYGTNATHYTNATHMGN CARTAYMGNCCNCCNATGGARTGYTGYACNATHGARTTYCCNGCNGGNYTNATHGAYAAR GCNGARACNGCNAGYCARGCNGCNGTNMGNGARATGAARGARGARACNGGNTAYGAYGTN GARGTNACNGAYATHTCNCCNTCNACNTCNYTNGAYCCNGGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CCNGCNGCNYTNTTYAARGGNMGNYTNTCNGARACNYTNTGYYTNYTN GAYATGMGNMGNAAYAARATHTCNCARATHCCNGARGAYATHGTNAARYTNAARGCNYTN ACNTCNYTNAAYYTNAGYAARAAYCAYYTNACNGTNGTNCCNGARTCNYTNGGNATGATG CCNTCNYTNMGNAAYATHCAYATHGCNGAYAAYGARYTNGAYTTYYTNCCNGGNAGYTTY YTNYTNACNATHTTYGARACNGTNGAYTTYAGYCAYAAYCCNTTY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNTAYTTYTAYCARAAYAARCARACNAGYCAYACNCARTGGGARTAYCCNCARGTNACN GCNGGN---GGNGARGGNAARGGNMGNGARMGNGARGAYGAYTCNMGNACNYTNTCNTCN AARTCNAARGGNGGNGGNGARAGYAAYAGYMGNGAYGGNMGNAAYTCNAGYAGYMGNCAY CAYAGYMGNAARGARAARGARAARGAR------------MGNAGYAARMGNGAYAARCAY AGYGCNTCNTCNCAYCAYCARMGNAARAARAARMGNMGNMGNMGNGARCAYAGYAGYGAY AGYAGYAGYAGYGAYGAYGARAAYACNMGNTCNAARCARMGN---CAYMGNAGYAARMGN AARAARCAYGGNAARACNGAYAARTCNCCNAGYATHGARGTNATHGAYTCNGAYGARGAY ATGGARGTNATHGARGCNAGYCCNTCNCCNGARCARGGNAGYGAYGAYGARMGNCCNATH TCNTCNGARYTNTCNCAYYTNGTNGCNGAYTAYGGNTCNGARCAYGAYGARGAYGGNAGY GAYCARGTNGAYGAYAAYGARAAYGAYAAYATHGARAAYAAYGARGARGARTAYGAYGGN ATHACNACNAAYACNACNGCNGTNAARGAYAARYTNGGNTCNGTNGGNGARAAYATHGAY GGNGARGAYYTNGGNGARGAYGGNTCNGTNCARGARGAYGARAARGARGARGAYGARATH ---AAYACNGCNGTNATHGTNMGNGCNCCNCARATHATHGTNCCNCCNTAYGTNGCNGCN GTNAAYCARCCNCARYTNTAYTCNGCNCCNAGYYTN---TAYGCNGCNCCNTCNACNGCN TCNTCNCCNCAYCARAAYAAYGTNGARCCNGARCCNAARTCNCARGARACNGCNGTNGAY AARGTNACNAARAARAARAARAARGARAARTCNGGNAARGAYAARTCNYTNACNACNACN GGNAGYATHATGATGAARAARAARGGNATGACNTCNATGGTNCARAARTGGCARAARGTN AARAARGARGTNGARAARGARAAYMGNGAYAARGARYTNMGNCARGCNGCNATHMGNGAR AARATHAAYGARYTNAARGTNGTNTTYMGNATHAAYGAYAAYGGNYTNGGNCCNGAYYTN GTNCARCARGTNTTYYTNGARMGNGGNTGGGTNGARTAYGAYGARGARATHCAYAAYCCN GARGARTGGAAYYTNTGGTGGMGNACNTCNMGNTTYMGNCARGGNGARTAYAAYAAYYTN YTNCCNTGGCARCAYATHAAYCAYTTYCCNAGYTGYACNGTNYTNACNAARAARGAYGCN YTNTGYMGNAAYYTNMGNAARATGAARATHATHCAYGGNYTNAAYGTNTAYAAYTTYAGY CCNAARGCNTTYAAYYTNCCNAAYGAYTAYACNAARTTYGTNTCNGARTAYGCNGCNTGY MGNCARACNTCNAARAARGAYACNCCNCCNGTNATGTGGATHTGYAARCCNGCNGARTCN TCNMGNGGNMGNGGNATHTTYATHTTYMGNGARYTNTCNGARYTNCARTAYGAYTGYAAY GCNGTNGTNCARCARTAYATHAAYGAYCCNYTNYTNATHGGNGGNTAYAARTTYGAYATH MGNATHTAYGTNGCNATHCCNAGYTAYCAYCCNYTNCARGTNTAYATHCAYGARGARGGN YTNGTNMGNTTYAGYACNGARAARTAYGAYYTNGAYMGNYTNGAYAAYGTNTTYGCNCAY YTNACNAAYACNAGYATHAAYAARTTYAGYCCNTCNTAYACNGCNGARAARGARGARGTN GGNCAYGGNTGYAARTGGACNATHTCNCARYTNMGNMGNTAYTTYATHCARAAYAAYATH GAYGAYGCNMGNATHTGGCARCARATHACNAAYATHGTNATGYTNACNATHYTNATGCAR GCNCCNTCNGCNCCNAARCAYGCNAAYTGYTTYGARYTNTAYGGNTTYGAYATHYTNATH GAYAAYTCNYTNAARGCNTGGYTNYTNGARGTNAAYTTYAGYCCNGCNYTNAGYTCNGAY TGYCARGCNGAYGTNATHGCNAARAARGGNATGYTNCAYGAYYTNATGTCNYTNYTNTAY AAYMGNGGNGARATHMGNAGYGTNYTNTCNATGATHGAYGGNGGNAAYAARAGYAARAAR CARGGNAAYAAYGTNACNGGNYTNTCNAARAAYATHTCNGCNTTYGGNATHGCNGGNTTY GTNMGNTTYATGGARGGNTAYTAYATGATHYTNATHACNAARMGNAARAARGCNGCNATG ATHGGNCAYCAYACNATHTAYAARATHGARGAYACNTCNATGYTNTAYATHCCNAAYGAY ACNGTNMGNATHATHCAYCARGAYGARAGYNNNTAYGTNAARATGTTYCARAAYGTNGAY YTNTCNAGYAAYTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CARCARCARCARCARCARCARYTNCARGAYYTNCAYCAYCCNTTYCCNATHTCN CAYCCNACNATGTCNATGCAYAGYGTNAAYTCNCAYCCNACNACNACNYTNCARAAYACN ATGTGGGCNAAYTCNCARCAYACNGARAGYATHTGGTCNCARCCNTCNTCNATGTGGGAY ATHGAYAAYACNAGYGARACN---TCNCARGCNTAYAARATHCARYTNGARAARGTNAAR ATGCARMGNGARGARGARAARATGGAR---GARGARMGNYTNCARCARGARYTNYTNGAR AGYAARCARAARGARATHYTNAARCARCARCAYGCNYTNGARAARCARMGNGARCARGTN MGNAARGARAARGARGARYTNGARMGNGCNMGNYTNMGNAARATGGARGARATGMGNAAR GARGARGARMGNYTNGCNCARYTNGARYTNGAR------------------AGYGARAAR GARMGNMGNCARCARGARGCNMGNCARAARGCNCAY------------------------ ------------GARGAYGARMGNAARAARMGNGARCARGARYTNAARAARCARGARGAR AARCARMGNAARGARGARGARAARYTN---GARMGNAARMGNCARGARGARGCNMGNATH AARAARGAR---------------CARGARGARYTNMGNMGNMGNAARGARGARGCNAAR CARAARGARGARYTNMGNAARCARATGGAR---------YTNAARYTNATHCARGARGAR GARGARMGNATGAARMGNGARATGGTNGARAARGARAARCARGARGCNGCNAARAARCAR AAYATGGARTTYCARMGNCARCARGARTCNYTNMGNAARYTNCARCARGTNCARAARGAR CARYTNGCNAAYATHCARYTNCCNGCNTCNAGYAAYTGGGCNAAYAAYGGNTCN---CAR GGNGGNGCNGTNCAYTCNAARTCNYTNACNGARATHCARGARGARGARGCNMGNAARGAR AARGARMGNCARMGNGARGTNCARYTNCARAARGARMGNATGCARGARCARGCNGCNATH ATHCARCARCARCARAAYCARAARACNTGGGCNGCNCARGCNMGNGGNAGYGGNGGNMGN GGNYTNTCNYTNYTNGAYATHCARCARCARGARAARGARAAYGCNAARAARTCNGAYAAR GGNAARGCNCAR---AAYCAYCARGCNAARCCNACNYTNGGNAGYGGNGGNGGNAAYTGG YTNGGNTCNGGNCCNGGNYTNTGGGGNACNAAYAGYACNTGGGARAGYAAYACNGCNCCN GCNTCNACNACNAGYATHTGGGAYATGGGNGTNCCNCAR--------------------- ---TCNATHAARTCNCARYTNGGNAARAAYAGYYTNGGNAGYGGNCARAAYGCNTCNCAR CARCARTCN------AARAARAAYAGYAARACNAAYAARAARGCNGCNGCNCCNGCNGTN AARGARGTNGARACNGTNCARAARYTNTTYCARAAYAARAARCARGAYGGNTTYTCNGCN TGGGTNACNGARAARYTNTCNAARTTYTCNTCNAAYATHGAYGTNCCNACNTTYGTNTCN TTYATHGTNGAYGTNGAYAGYCCNGAYGAYGTNYTNGAYTAYGTNAARACNTAYYTNGGN GAYAAYAARGARACNCAYGAYTTYACNMGNCARTTYYTNGARAARMGNAAYCARTAYAAR AAYCARATGMGNYTNCARAARCARYTNGARGARGAYAGYATHTGGGGNCCNGCNCCNGCN ATHAAYCCNCAYTCNGCNTTYTCNTCNGARGCNTCNAARTCNGCNGGNGARGGNGGNYTN GGNAARTCNAARAGYAARAARAARAARAARGCNCARAARYTNGAYGTNAGYATHYTNGGN TTYACNGTNCAYGCNGAYCCNAAYMGNAARAAYGCNGGNGARYTNGARACN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AARCARMGNGARCCNGARATH GAYAAYCCNTCNATHATHCCNTTYAAYMGNCCNGAYCARGARMGNYTNAARGTNAARATH YTNGARGARGARMGNCARMGNGARTAYAAYCARACNAARGCNCARATGGGNGARMGNGCN MGNMGNMGNGARGTNACNCCNGTNCARGAYTAYGAYCCNTCNGTNCARGARCARGARAAR MGNATHCARAARGARMGNGARCARMGNGARTAYAARGCNATGYTNGAYAARCARCARGAY TAYCARAARAARATGATGATGYTNCARCARGGNGTNCCNTAYGARAAYATH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GARYTNMGNGARGARMGNAGYTCNYTN GARAARGARYTNYTNYTNTCNGAYAAYYTNACNTAYACNCCNCARGTNGAYAARCCNGTN TTYAAYGARTCNYTNAARAARYTNGCNCCNACNCAYCCNTCNTCNACNTCNATHAAYATH ACNACNAARCAYAGYCCNGTNAARGCNAAYCAYCARATHGCNACNGCNACNGARATHTGY AAYAARGCNAAYGARGARTAYGTNCARGARAAYTAYCARAARGCNGTNAAYYTNTAYACN GARGCNYTNGCNGTNGAYGCNAARMGNGAYGAYATHTAYTGYTTYMGNGCNCARGCNCAY YTNTCNYTNGGNAAYACNACNGCNTCNATHAARGAYTGYGAYGARGCNATHAARATHAAY CCNCARAAYCARAARGCNTAYYTNAARAARGGNTCNATHYTNATGAARATGGAYGARGTN YTNCARGCNGARAGYATHTTYAARGARGGNCARAARCARTGYTCNGGNGARAARGAYTTY YTNGARTGGATHTGYAARGTNGARAGYMGNATG---------------------AARGAR YTNGGNATHGGNCARAAYCARCCNATH------------------GCNGCNYTNAARTAY AAYTGGTAYCARACNCAYACNCAYGTNATHATHAAYGTNATGGTNAARAGYGTNAARAAR GARGARYTNGGNYTNGAYGTNGARCARMGNTCNTGYAAYGTNACNGTNYTNMGNGARGCN YTNTCN---AAYCAYYTNAAYATHCCNYTNGCNCAYGCNATHGTNCCNGARCARACNCAR TCNAARYTNTTYGCNACNAARATHGARATHAARYTNAARAARTCNGARGGNATHCARTGG GTNAARYTNGARGGNGAYCCNAARGARGARGAY---ACNATHYTNCCNCCNTGYGCNGCN CCNGTNGARGARACNGARGCNCCNACNTAYCCNAGYTCNTCNCAYCAYACNMGNGAYTGG GAYAARYTNGCNGCNGARGTNACNGARGARGARAARAAYGANAARYTNGARGGNGAYGCN GCNYTNAAYCARTTYTTYCARAARATHTAYTCNGAYGCNTCNGAYGAYACNAARMGNGCN ATGATGAARTCNTTYTCNGARTCNGGNGGNACNGTNYTNAGYACNAAYTGGAGYGARGTN GGNACNAARCCNGTNGAYGTNAARCCNCCNGAYGGNATGGARTAYAARAARTGGGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYTGYGCNGGNGAYTCNGTNTTYYTNGGNTCNTTY GCNGGNGARYTNMGNTCNATGCCNATHTCNGCNGCNACNAAYGAYTTYGTNAGYACNGTN TGYCAYTCNTCNCCNYTNATHAARATHAGYACNACNATGGTNGAYCCNGAYYTNATHATH ACNTCNACNTTYGGNGCNACNCARAAYTGYGCNYTNTGGGGNTAYAARMGNGAYACNGAR ACNTGYGTNGTNAARTAYMGNTTYGAYGARACNTCNGCNACNATHGCNAAYYTNAGYCAY GAYMGNTTYATHGGNACNAARGAYATGAARGCNACNATHTAYGAYACNGCNACNGGNAAY AARYTNCARACNYTNTTYGAYGARAGYAARGCNAAYTAYTAYAARTTYAAYGARGCNTCN TTYAAYCCNACNGAYGAYYTNGTNYTNAAYGAYGGNAAYYTNTGGGAYGTNMGNTCNGGN AARATGATHTAYAARTTYGAYAARTTYAAYAAYTAYAGYAGYGGNTGYTTYCAYCCNAGY GGNYTNGARGTNGTNATHAAYTCNGARATHTGGGAYATGMGNTCNTTYMGNYTNYTNCAR ACNGTNCCNGCNYTNGAYCARTGYCARATHATGTTYAAYCAYGGNGGNGAYGTNATHTAY GCNATHMGNGTNGAYGAYGARCCNGGN---GAYACNYTNATGMGNMGNGAYTAYGCNTCN ACNYTNMGNACNTTYGAYGCNTAYAAYTAYAAYAGYATHGGNACNTTYGAYYTNAARACN AAYAGYATHTTYGAYGTNGCNGTNGAYMGNCAYGAYCARYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CAR CAYTGYTTYAAYCARGTNAARACNACNYTNGCNTCNGAYCCNGARMGNTTYCAYAARTTY YTNTCNYTNYTNAARGAYYTNAAYAARGAYMGNACNAGYCCNGTNGARYTNTAYYTNGAY ATGGCNTCNYTNYTNTCNGAYCAYCARCARYTNGTNGARGAYTTYGCNGGNTTYYTNYTN TCNTTYCARGCNATHGARTGYCARTGYTTYTCNAGYAAYCAYCARTAYACNCARATHMGN CARTTYYTNMGNCARATHGARGTNAAYTGYGCNAARTCN---AGYAAYGGNTAYCARMGN ACNYTNAARGCNYTNACNACNTGGACNAAYYTNTAYCARAGYGGNCARGTNGTNAARAGY YTNAARGAYCARYTNATGAAYGTNYTNAARAAYGTNCCNGGNGTNYTNGAYGAYYTNGTN GGNTAYTTYYTNGAYGGNAARGTNAGYGTNTGYGAYTCNATGGAYTTYGARGARGTNTGY YTNGAY---------------GGNAAYAAYGTNGAYGAYTTYGARACNGTNACNYTNCCN AARGARAARGGNGAYTAYAAYACNACNACNTGYACNTGYCARTGYCAY---AARCAYCCN MGNGAYAARATGTTYCARYTNMGNMGNAARCAYTGYATHTCNTGYAGYYTNGTNGTNTTY CARGGNCARGCNGTNYTNMGNACNAGYCARMGNAAYATHAARCCNGTNAARATHACNTAY CCN---------CAYGARGAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNCCNCAYAARAARTCNTTYYTNACNGGNGAYACNMGNGAYTCNGTNGAY TCNGAYACNAARATGTCNACNATG---GAYACNGARGAYATGMGNYTNMGNAAYACNATH AGYGTNGAYGCNGAYAAYACNAARGAYTCNGCNGCNTCNGAYTCNGTNACNGARGGNCCN ACNCCNACNAARAARYTNAARMGNGGNTGYMGNGARGGNYTNGTNGARGARATHAAR--- ---------AARGTNACNGCNGARACNYTNTTYGARTAYCARTGGCCNCARGAYGARGGN GARTGGCAYYTNYTNCARGARCARGTNAGYGARTTYYTNAARGTNAARTCNTTYAARMGN AARTAYCCNGAYYTNTAYMGNMGNGTNTGYGAYAARGARGARAARGAYTTYYTNMGNGAY AARGGNGTNGTNACNGARACNCARTCNGAYYTNGGNYTNACNGCNYTNMGNAGYGARGAR GTNTAYGAYYTNATGATGAARGAYTAYGGNGAYTAYTAYCARGARTAYYTNACNGTNYTN CARGARAARCAYAARMGNGTNATGMGNGARAARCAYAARGAYTAY---ATHGCNGAYYTN GAYAARTCNAARATGGARGCNTAYMGNMGNAARGCNGCNAARAGYGCNGCNGARTTYAAY GCNAGYYTNATGMGNGARAARMGNGARGARMGNCARGCNTAYTTYGAYYTNCARACNTGY ACNATHCAYCAYGCNAARAAYMGNTTYMGNTCNATHCCNGCNAGYCARACNAARGTNGGN TCNTAYCCNGTNTCNGTNATHCARGGNCARTAYCARGAYAARTTYMGNMGNTTYGAYCCN GARGAYYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYGAYACNYTNCARAAYACNGTNGAY YTNTCNAARCAYGAYGTNMGNTAYGTNTCNTCNGAYGARGTNAARGCNGGNYTNTGGACN TCNAAYACNAARYTNTTYTGYATGGGNGGNGGNTAYGAYYTNGGNTAYATHGARTCNYTN GGNAAYGTNGGNGTNMGNYTNATHMGNGARTTYGTNAAYGGNGGNGGNTCNTTYYTNGGN ATHTGYGCNGGNGCNTAYTTYGCNTGYGAYTAYATHGARTTYGAYCARGAYGGNCCNYTN GARGTNGTNGGNGARMGNCAYYTNAARTTYTAYGGNGGNAARTGYGTNGGNCCNGCNTAY AARGGNTTYGAYTAYCAYACNAARAARGGNGCNGTNGCNGCNCCNATHACNTAYAARAAY ATH---YTNAAYGCNTAYTCNGARGGNGGNGGNYTNTTYATHCCNTAYAARGGNTCNTCN CARAAYTAYAAY---AARACNYTNGGNMGNTAYAARTCNATHGAYGAYACNCCNGCNGTN ATHGTNAARTGYMGNTGYGAYAAYGGNACNGCNYTNYTNTCNGGNGTNCAYATHGARTAY CCNTCNCAYAAYYTNAAYGCNGARGAYCARTAYYTNMGNAARATHYTNCCNCARYTNACN CAYAGYGARAARMGNMGNAARTTYGTNTTYATHGAYATHYTNAARCARYTNGAYGTNGCN TGY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGNTTYTCN TTYGGNAGYACNACNTCNACNTCNGGNAAYACNGGNTTYTCNTTY---------AGYACN TCNTCNTCNACNAGYGGNTTYTCNTTYACNAGYACNACNTCNTCNTCNAGYACNACN--- ------------------------------------------------------GCNGGN ------------------AAYAGYGGNTTYTCNTTYGGNGCNYTNGCNGCNAARGCNATH TCNACNAAYAARGTNGCNACNAGYCARGGNGGN------------GAYGAYGAYGAYTAY GTNCCNCCNAARCCNGARGTNAARGARATHCARGARGARGGNGCNATHTTYTCNAARMGN TGYAARYTNTTYTAYCARAARGARGGNCARTGGACNGARMGNGGNGTNGGNAAYGTNCAY YTNAARCCNYTNGAYGGNGAYAARACNCARYTNYTNATHMGNGCNGAYACNAAYYTNGGN AAYATHYTNYTNAAYATHAAYGTNACNGGNGCNYTNCCNGTNTCNMGNCARGGNAARAAY AAYGTNGTNYTNGTNTGYGTNCCNAAYCCNCCNYTN---------------AARGARGGN GAYGARCCNAARCCNATHTCNATGYTNGTNMGNGTNAARACNGGNGARGARGCNGAYGAR YTNYTNCARAARGTNGARGARMGNAARAARYTNGTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GGN GTNGTNGCNAARAARTCNATHAARGTNMGNACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CCNAARAAYTGGATGACNATHTCNAAY ATGGCNCAYTAYATGAARTAYGCNATGGGNAGYTAYGGNTGGCCNTTYTAYATGTAYGAR TAYYTNATGACNGGNYTNTGYMGNYTNTGYACNCARTGYMGNTGYGTNTCNTGYATGMGN GGNAGYAAYCARGTNTTYGAYGAYAAYTGYTGYCARTGYAAYACNGCNGCNATHAARAAR YTNTCNMGNTCNAARAGYTGYGAYYTNGTNCAYGTNACNTTYCAYAAYAARTTYAARGAR ATHCCNTTYTAYGTNGCNGTNGAYCARGGNAARAAYACNGCNGTNATHAGYATHMGNGGN ACNYTNTCNYTNAARGAYGCNYTNGCNGAYGTNTCNGCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYGARGARGAYYTNATHGGNTCNCARGAYTCNAGYTAYAGYGAY GGNCCNGAYYTNCCNGARGARAGYATHYTNCAYGTNTGGCCNGARGARGAR------GAR AAYATHGGNACNCARYTNACNCARACNAGYGCNGARGCNYTNMGNGAYAARYTNATGAAY TTYYTNAARGAYAAYCARAGYATHTAYGARAARATHYTNATGTAYGARGCNYTNGARYTN GAYGTNYTNAARAARCARATHTCNGAYGCNGGNATHMGNATH------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GARGCNTCNGTNAAYTCNATGMGNTGYAARYTNACNGGNTGGATGGAY GARYTNAARGARAARATHYTNGGNGARATGGARAARTCNYTNACNTGYTCNGCNCARGTN CARAAYAAYGARTTYAARAARGCNACNAARTGYGTNYTNGTNGARAARGGNACNYTNCAR AARGARGTNAAYAAYYTNACNGARMGNGTNAAYGAYYTNGARTGYTCNYTNGGNCARAAR AAYACNYTNGTNAARAAYATGTCNGAYAAYATHTGYTCNCARAARCARAARYTNGAYCAR GCNAARTGYTTYTAYGCNTGGAARACNGARTGYGCNGAYAARGAYMGNGARTGYTTYACN GARAARYTNGCNTAYGARCAYCAYAGYAARAARYTNGCNYTNMGNGTNYTNAARGCNTGG TAYAGYYTNATHCARTCNMGNTGGMGNTGYMGNGTNGARMGNCARTGYCARACNCARGCN AARAGYYTNTGYATGAAYYTNAGYAGYGAYTAYGARATHAARGTNTGYATGYTNAAYGAR AARATHCARTCNYTNGARGARAARGTNTGYYTNYTNCARCARGARMGNGARATGTAYTCN GARCARGTNAARAARGCNTTYATGMGNGGNATGTGYGCNYTNAAYGTNGARACNATGTCN ATHYTNACNGARAGYGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNCCNYTNGTNTAYCARYTNACNAAYCARGGNCARGGNCCNGGNCCNYTNACN GCNGCNYTNCARGCNTCNGGNGTNTTYACNCCNGGNGGNTCNYTNAAYATHGCNAGYACN CCNACNYTNACNYTNAARCCNYTNAARCARGARCCNTCNGARYTNATHMGNMGNCCN--- TCNGAYAGYGGNGCNGCNAAYGARGAR---------------TCNGCNACNCCNCCN--- ---------------------------------------------------ATGAGYTCN GAYATHTGYTAYAARTGYGGNGGNMGNGGNCAYTTYGCNMGNGAYTGYMGNTTYGGNCCN CCNGGNGGN--------------------------------------------------- ------GGNCARAARTGYTAYAARTGYAGYMGNATHGGNCAYTTYGCNMGNGARTGYACN CARGAYCARGARMGNTGYTAYAARTGYAAYGGNTTYGGNCAYATHGCNAARGAYTGYGAY AARCCNATHTCN---ACNGGNGCNTGYTAYAAYTGYGGNAGYGCNGAYCAYYTNCARMGN GAYTGYCCNGARGCNATHGTNAARTCNTGYTAYMGNTGYGGNCARTCNGGNCAYYTNGCN AARGARTGYCCNGCNGAYATGCCN------------AAYAARCCNTTYGCNGAYGAYMGN AARTGYTAYACNTGYGGNGGNGTNGGNCAYYTNGCNAARGAYTGYCCN------------ TCNCCNMGNMGNGARTGYTAYNNNNNNNNNNNNNNNGGNNNNNNNNNNNNNNNNNNNNNN NNNNNNCCNCARTCNAAYACNACNTGYTAYAAYTGYAAYGARACNGGNCAYATHGCNMGN GAYTGYACNGCNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNATHMGNTCNATHCAYACN TTYGARGARAARATGAARATGACNYTNYTNCCNACNGAYGARAAYGARGAYATHGAYATH CARTAYATHATGACNMGNGAYGARGAYMGNGGNGARCCNATHCAYATGYTNAARACNGCN CCNAAYGAYGARTAYATHGGNAARATHMGNAARMGNYTNCARGARGAYGCNTCNGCNMGN GARGARMGNGARNNNMGNMGNMGNAARGTNYTNGGNGAYCARATGAAYGCNCAYCARGCN CARGARGARGCNMGNMGNGARGARATGATGGTNAAYMGNYTNATGMGNCARTCNCARCAR GARMGNMGNATHGCNGTNCARYTNYTNCARGCNMGNMGNGARAARGARATHATHMGNCAR AAYMGNATHTCNMGNGARAARCARTAYCARGARMGNMGNCARAARGAYTTYGARGAYGCN YTNGAYYTNGARGCNGARATGTCNGCNYTNCAYAARYTNGARTAYGCNGARCARATHAAR MGNGAYCARGARYTNCAYGAYCARATHGCNGCNCAYMGNGCNGARGARAARTAYAARAAY CAYTAYGAYATGTGYGCNGARATGGTNGGNAGYATHYTNGAYTTYTCNTGYAARATHGCN GARTAYMGNGARYTNACNTCNAAYYTNYTNCCNCCNAARYTNATGMGNGARTGGAARYTN YTNTTYACNAGYGGNCARCCNYTNTTYGARCCNYTNGARGARGTNAGYAGYGARYTNACN CCNGARCARGTNYTNGARGARGAYMGNCARCARYTNYTNGAYGARGGNGAYTTYATGGAR TAYAARGGNATGGGNGGNGARTGGAAYCCNCCNGAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNYTNMGNCCNTTYGCN---ACNGGNYTNATHGGNMGNAARGGNAARYTNATHCAYACN ACNCCNAARAARTGYGGNGARGCNYTNTAYMGNGARAAYATG------TTYGGNTAYAAR GARCCNMGNTAYATGCARYTNGCNGGNACNGCNTTYAGYGCNTTYYTNTGGTAYTGGATH YTNTAYCAYTGYTAYTTYGARTTYGARCAYYTNGTNATHCARGARAAYTCNCARATGAAR YTNATGATGAAYAGYGAYACNATGACNACNGARGAY---YTNGCNATHYTNAAYAARYTN GGNGARATHCCNGTNATHAAYGAYAGYTGGTTYAARGCNGCNGAYTAYTAYTCNAARGTN AARGAYTAYAAYGCNYTNATGMGNTTYACNYTNGCNYTNGCNGARTCNAGYGTNAARAAR GCNGGNGARYTNTCNGCNCCNGTNYTNYTNCAYTAYAARCCNCARATHGAYAAYATHGAY GARTAYGCNTGYAARAARYTNGAYCARYTNGARACNAARTAYCCNTGYATHAARCARCCN ACNGARCARTGGAARGARACNTGYTCNGAYYTNGTNGAYCCNGTNYTNGGNMGNGTNAAR CCNGTNATHTCNCARGTNCARGGNATHATHGAYAAYGGNAARCARACNATHAAYACNATH AARACNACNAGYACNGGNATGGTNGARAARGCNAARACNACNAGYGTNGGNACNGCNGCN AAYATHTTYAAYGCNAGYTTYGARACNTAYCCNGGNMGNATHGTNACNMGNACNGTNGAY GGNGCNATHGGNATHGCNGARAAYYTNGTNGAYAARTAYYTNCCNGAR---GARGARGTN GAYGAYTGYAARAAYGAYGAYGAYATGTCNGAYGCNAGYAGYGAY--------------- ------GCNAGYGGNATHGARCARATGGARCARATGGCNCCNACNCCNCARMGNGTNTTY GTNCAYGCNGGNTGYGTNACNGARAARYTNMGNAARMGNATGTAYCARMGNGCNATGAAR GAYYTNACNTAYGCNMGNTCNMGNACNGCNTCNGCNYTNAAYMGNATGAARAAYACNGTN GAYYTNGCNGAYTTYGCNMGNTCNAAYATGACNAAYGTNAARGAYAARGTNGAYCAYATG TGGAAYGARGTNATHGCNGARAGYGAR---------------GGNCARGAYAARACNGTN TTYAGYGGNAGYGTNGARGAYMGNATHATHGCNYTNGGNCARYTNGTNGCNMGNCARGTN AARACNGGNATHAAYGARTTYGAYAARGCNTGYGCNGARATGTCNGARTTYAARAARGAY CCNATHTCNAARTCNAARGARTAYAARGAYYTNATHGGNACNTTYATGTCNGTNGAYTCN YTNAARAAYYTNACNTCNCARAGYATHAGYAARGCNAARGARTCNGTNAAYYTNATHCAR CARMGNATHCARAGYATHATGACNYTNCAYCCNAGYYTNAGYTGGGTNGCNGTNGAYATH GAYATGGARGAYATHCCNYTNAAYGARTCNGAYYTNGAYCCNMGNYTNAAYYTNTCNGCN ATGCARGTNTTYAARYTNAARAARAAYTGGAARGGNATHAARMGNMGNYTNGARGAYACN GGNGTNGARATGYTNATHMGNYTNTTYMGNGTNGCNCCNTCNGCNCARAGYCAR------ ---TAYMGNCAYYTNGARACNGARGARAGYYTNMGNATGAGYGARGARYTNGARAARCAY GCNGGNAARATGATGTCNAGYYTNGAYGAYATHGTNAAYAAYATHGARGAYGTNGAYTAY GCNYTNGARCARATHTCNAARATGGCNCAYGAYCAYYTNCARYTNGAYGGNTTYTCNTCN GAYCARTTYATGYTNATGGARCARCCNTTYYTNGAYGCNGTNMGNATHATHYTNGAYGAY MGNTAYACNGAYAAYATGGAYGTNATHTAYMGNATHYTNATHAARTTYATHYTNGARCAY YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARACNGTNTTYATH ACNGGNGGNGCNCARGGNYTNGGNATGGGNATHGTNAARAAYTTYYTNGARAARMGNGCN AARGTNTGYTAYGGNGAYATHAAYCARGARGTNGGNAARGCNACNGARGCNGARYTNCAR GCNAARTAYGGNAARGAYAARGTNATGTTYGTNGCNTTYGAYGTNACNGAYGAYMGNCAR TTYMGNGARTCNTTYGCNCARGCNGTNGGNMGNTTYGGNAAYATHGAYATHTTYATHAAY AAYGCNGGNATHYTNAAYGARGGNATGTGGGARAARATGYTNCARATHAAYTTYGCNGGN ACNGTNMGNGGNACNAARATHGCNATGGARCAYATGMGNAARGAYAARGGNGGNAARGGN GGNMGNATHGTNAAYGTNTGYTCNATHYTNGGNYTNGTNGARCAYTAYGCNACNGCNGTN TAYTCNTCNACNAARCAYGCNATGMGNGCNTTYACNACNTCNACNTCNATGACNCCNGGN ATHGARTCNACNATGGGNATHGARATHGCNGCNYTNTGYCCNGAYGCNATHAAYACNGAY YTNATGACNAARYTNGAYGARTCNAARATH------------GGNGAYTAYGAYGARGTN AARCARGTNGTNGAYCARATGGTNATGCCNGTNTCNGTNGTNGTNGAYGGNATGTTYACN YTNGTNGARAAYGARAARTCNATHAAYGGNGCNYTNYTNYTNGTNACNAARACNGARAAR AGYTAYCARAARATGAGYAARGTNGAYYTNGGNCARCARTGGCCNGCNCCNGCNTAYGGN AARGTNTGYACNGAYATHTCNCARTGYGARGCNGGNGARTGYTGYCARATHATGAGYGAR TTYATGATHGTNTCNAARMGNGAY------------YTNGTNACNTCNYTNCCNACNYTN ACNAARACNGGNACNTGYGARAARTAYMGNYTNGARGGNTCNAARTGYGGNATHTTYGAR AARGCNAAYGGNTAYTGYGGNTGYGARGCNGGNACNMGNTGYCAYGGNCARGARGTNCCN ATHAAYTCNACNMGNAAYATHGCNAARMGNGAYATGMGNCCNGCNMGNCCNGGNTAYGAY TGGCARTAYACNTGYACNAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARMGNCAYYTNAARATHCARMGNYTNAARMGNAARATGGGNMGN GAYTTYGAYCCNYTNTGGATGTCNCARMGNGARCCNAARGAYACNACNAARYTNGARATH AARGAYACNTTYGAYGARAGYYTNAARCCNCARAARTCNCAYTTYAAYACNMGNAAYATH TCNCARAARYTNATGGCNGTNYTNMGNGARGARATHTCNTCNAAYACNGGNAAYAARACN AAYTCNACNCAYGCNGTNGAYTAYATHAARGARGGNMGNAARATHGCNTCNAARATHGCN GARACNATHGAYAARTGGYTNATHTCNACNGGNTCNTGYCCNGTNTAYTAYAARTGGGAR GAYTTYGGNGTNATGTAYTGGCCNMGNTGGGTNAARAARGGNATGTGY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATHGCNTCNGCNGCNGTNGCNGTNGTNATGYTNYTNATHYTNATHAGYATGATHGTNTTY GCNTCNTGYTAYTCNGAYTCN---------TGGATHAGYTCNAAYATGMGNMGNGARGGN AARGTNAARATGCCNAARTCNTAYTTYMGNAARAARGARGARGCNAARCARMGNCARMGN GARGCNMGNGCNMGNTCNYTNMGNCCNTCNACNGTNGGNGGNGTNCCNCCNGTNGCNGTN GTNGAYAARGAY------------------ACNATGGTNCAYGGNTGGAAYCARCAR--- ---------TCNTCNCCNTAYGARGARAARACNTAYAGYATHGARYTNGGNGARGARAAY GAYAAYGARTTYCARATHGARACNACNATHGTNGAYAAYGARGTNYTNGAYGTNGGNCCN TTYAARAAYATG---GARTCNGGNAGYGCNMGNCCNGTNGARGGNAAYGTNTAYAAYAAY GCNTAYATHTAYAGYAAYAAYGAYMGN---------------------------TCNCCN ACNATGGCNAARYTNATGCARAARGAYGAYGCNYTNAAYYTNATHGCNAAYGTNGAYAAY TAYATHTTYGAYTGYGAYGGNGTNYTNTGGGARGGNACNGTNCCNATHGARGGNAGYYTN GAYACNATHYTNAARYTNAARCARYTNGGNAARAARGTNTAYTAYGTNACNAAYAAYAGY TCNAARACNMGNCARGAYTGYGTNGAYAARTGYMGNTCNYTNGGNTTYCCNGCNGARAAR AAYGAYATHATGTGYACNGCNTAYATGGCNGCNCARTAYYTNAARATGAARAAYTTYAAR GGNAARGTNTAYYTNGTNGGNYTNGARGARAGYATGGGNAARGARYTNAARGARGTNGGN ATHCCNTAYATHGGNACNGGNYTNGAYCCNCAYCAYTCN---ACNTTYGARGGNTGYYTN ACNGCNGARYTNGAYCCNGARGTNAAYTGYGTNYTNGTNGGNTTYGAYCCNTAYATHAGY TTYTTYAARATHTGYAARGCNGCNAGYTAYYTNAARAAYCCNGAYTGYATGTTYGTNGCN ACNAAYGARGAYCCNTGYYTNCCNATGAARGGNAARATHYTNATHCCNGGNACNGGNGCN ATGGTNGCNGCNATHAARGCNCCNTCNGARMGNACNCCNACNGTNGTNGGNAARCCNGAR ATGGGNATGTTYGARGTNYTNCARAAYACNCARAARTTYGAYCCNGCNMGNAGYYTNATG GTNGGNGAYMGNYTNGARACNGAYGTNMGNTTYGCNCARMGNTGYGGNATGAARTCNTTY GCNGTNYTNTCNGGNCAYTGYTCNAARGAYGAYGTNGTNAAYTCNGCNTTYGGNATHACN GCNGAYYTNTAYGCN------------------------------------------MGN GAYGGNMGNGGNAGYMGNAAYAGYTAYGGN---------GGNGAYGGNYTNYTNGGNGAR GGNCCNYTNGGNGGNGGNGGNGGN---------GGNCCNATGATGGGNGGNAAYCCNATG ACNCARYTNGCNYTNGCNCARTCNYTNYTNCARCARCARCARCARYTNGTNAAYGCNGGN TTYGGNGGNGGNCCN---------GGNGCNYTNGGNGGNTTYCCNGGNGGNATGCARGGN ATGGGNYTNYTNCARCARCAR------------------------CARATGMGNCCNGCN CAYGGNYTNGTNGGNGGNATHAAYAAYGARMGNAARMGNAGYGGNGGNCAYATGMGNMGN GAYCAYGAYGARAARMGNGGNMGNMGNGAYTCNTGGGGNMGNGGNGAYMGNGAYMGNTCN CAYGGNAAYCARAAYMGNMGNGGNCARGAYAARGAYMGNMGNGAYTCNGCNAARAARAAY GAY---------------------------GARGAYTAYGAYCCNGCNGARCCNACNGAR GAYGAYGAY------GARAARAAYAGYAGYGGN---TCNAAYYTNCAYTGYCAYGTNTGY GGNATHTCNGTNTAYGAYGARGARAGYYTNAARMGNCAYYTNAAYGGNYTNAARCAYAAR GCNMGNATGGAYAGYATHGCNAAYGTNCAYGCNATHMGNGCNCCNCARYTNAAYCCNMGN YTNAARGCNGARGARCAYYTNMGNAAYATHGARMGNAARGGNGGNMGNAAYCCNGAYTTY TTYTGYAARATHTGYAAYAAYGARYTNACNATHCCNTGGGARAARCAYMGNTAYTCNAAY ATHCAYAARCARMGNCAYYTNCARGTNMGNAARGGNTGYGGNTGGTGYAARGTNCAYGAY TTYGAYAAYTTYACNGAYGTNYTNGARCAYMGNGARACNGAYGARCAYMGNAARAAYGCN ATGGTNTTYGGNAARAARGAYGARGARAARGAYGGNTCNMGNAARMGNYTNAARGAY--- ---------------------GGNAARGARGTNGARGARGAYGARAARGARGTNGAR--- ------------------------GARGARGARGAYYTNACNATHCCNGARTAYGAYACN GARGTNCCNGTNGGNYTNAAYTAYGTNATHCCNGTNACNGGNTAYTTYTGYAARYTNTGY CAYAARTTYTAYAAYAARAARTCNGCNMGNGCNGCNCAYTGYGTNAGYGARGCNCAYTAY GCNAARTTYAARGTNGCNACNGARGCNAARATHGCNGARAARGARAARMGNGARGARGAR GCNMGNYTNAARAARGARATGGARGARGCNGARGCNAARGARAAYGGNGARGAYAAYGGN GAYGARGCNAARGARGARAAYATGGARGARGAYACNACNGARATGGARGARGGNGARGAR CARGCNGARGARGARGARGARGARCARGCNGARGARGARGARCARGCNGARAARGARGAR GTNGARGARGAYACNACNYTNGARGARATGCARGGN---------------------GAY GARGCNGARGCNGTNGARGAYAGYTCNATGGTNGGNGGNACNGTNGAYACNTCNAGYTTY GTNTAYGTNCCNGGNGARCCNTCNTCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CAYATHTCNTCNYTN ATHTCNCARTAYGARAARGTNGARGGNMGNCARATHAARGARYTNTTYAAYGARAGYAAR TCNMGNGGNAARGGNGCNGCNAAYGARGTNTAYGARGARACNGARYTNAARCAYGGNGAY AARATGTTYCAYMGNTTYYTNAARGARYTNCARAARTTYCCNCARCARTGYATHMGNTAY GARMGNAGYGGNCAYCCNYTNYTNATHMGNCARYTNGAYCAYYTNCARTCNATHATHCCN YTNTGYACNMGNTGYGGNGCNGTNMGNGTNTTYGARYTNCARYTNGTNCCNGCNYTNATH GCNAGYYTN--------------------------------------------------- ------------------------------------------------------------ ---------------------------------TGYAAYATGACNGTNYTNTCNATGGTN CCNAAYATHMGNGARACNYTNGCNAARAAYATGGAYGTNGAYGCNGTNAARGARATGYTN AARTCNAAYCCNGARAAYAARYTNGARYTNTGGGARGARYTNAARATHATGAGYGTNACN MGNGCNYTNGCNGCNGTNTAYGGNACNTGYATGYTNTCNGTNATGYTNMGNGTNCARYTN AAYATH------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MGNGARGARACNGGNTCNMGNGGN TTYTTYYTNCAYTGYGCNAAYMGNATGGAYCARYTNTCNCCNCARYTNCARTCNTAYATG CAYYTNCARATHTCNCARYTNTTYTTYAAYGCNGARAAYCCNGAYATHGCNCCNATHTCN ATHATHCCNYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN AGYYTNGAYAAYCCNGTNTTYAGYTCNTTYATHGGNTAYGCNGCNATHGTNATHTTYAAR ACNYTNATHATGTCNYTNYTNACNGTNMGNCARMGNATGAAYAARAARGTNTAYCCNTCN GARGARGAYATG---TCNTTYATGAARGAYAARMGNGCNTCNATHTCNACNACN---GAY ---MGNGAYGTNGARMGNGTNMGNMGNGCNCAYYTNAAYGAYYTNGARAAYATHYTNCCN TTYGTNYTNYTNGGNYTNATGTAYTGYACNACNGGNCCNTCNYTNGCNATGGCNAARYTN CAYTTYMGNGTNTTYACNGTNGCNMGNATHYTNCAYACNATHGTNTAYYTNGGNGGNATH MGNCARCCNTTYMGNGCNATHGCNTAYTTYGCNGGNCARGTNGTNAAYGTNTCNYTNGTN ATHCARYTNYTNMGNGTNGCNGCNTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TTYCAY ATHYTNGCNGCNACNATGGCNCARGAYATHCARAAYCARYTNMGNAAYATGACNYTNAAR ACNYTNATHACNAGYGGNAARGAYGTNTGYAGYGCNYTNATHAAYTGYYTNATHACNMGN TAYYTNAAYGAYAAYGCNGCNATHGAYTCNYTNAAYGAYMGNYTNMGNGARGTNTGYCCN ACNYTNTAYAGYACNGAYGAYGCNACNTGYTCNAARTCNAAYGARYTNYTNCARGCNGCN AARATHAAYCCNAAYATGYTNGAYAARGARMGNCARYTNCARGARGCNYTNCARYTNYTN AARAGYGTNTCNCARCCNYTNAAYYTNTCNGTNATHTGYTCNCARYTNGCNAGYGTNCAY TTYTAYYTNGGNATHGTNGARYTNGGNYTNAAYGARGCNAGYAARYTNGAYCCNCARGGN ATGGCNATHCAYTTYTAYAAYAAYGGNGARCCNCARGARGAYATHCARGGNATGCARGCN TAYATHGCNMGNATGGARTGYTAYAARTGYATHACNGAYACNYTNACNTAYYTNACNTCN GCNAGYATHAGYCARGGNCARATHACNAAYATHTCNTTYYTNGGNTCNTCNACNAAYGGN CARGARTCNAAYMGNYTNGARCCNCARCARGCNGARTCNTTYAARGARGAYGTNTTYAAY ACNGCNYTNMGNTGYGAYGAYTCNYTNTTYCAYGCNACNYTNTAYGARTGGYTNTTYAAY ACNAAYCARGCNGARAARYTNYTNGARATHAAYACNCCNTTYGTNGARCARTAYYTNMGN MGNAARGTNAAYYTNCAYACNGARAAYACNAGYGCNYTNGAYATGYTNTGGMGNTAYTAY GARAARGTNGARAAYTTYCCNGCNGCNACNMGNATHYTNACNCARYTNGCNGARMGNCAY GGNACNGGNGTNAAYYTNACNCARMGNYTNGARTAYYTNTCNMGNGCNGTNGTNTGYGCN AARAGYTCNACNTCNMGNYTNGGNACNTCNGCNGGNGGNGARACNYTNCAYGARYTNGAR GARAARATGGARGTNGCNMGNYTNCARATGCARATHTAYMGNTGYYTNAGY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNGTNGAYAGYYTNMGNCARTAYCARGAYAAYAAYGGNGAYGTN GAYYTNTCNMGNTTYGCNCCNACNACNCCNAGYCCNGARGAYGTNAAYTGYCAYGTNGAR ATHCCNGTNGTNCARMGNATHGGNGGNAARTGYATHAAYYTNGGNAAYAAYYTNGGNTGY CARGCNGGNATHTAYYTNTCNGTNGGNTCNCARTGY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNAARGAYTTYCAYATHCCNATHACNGTNGARCARGGNMGNGCNAARGTNMGNGARATH TTYYTNAARAAYAARCAYGTNACNGAYATHMGNGTNATHGAYATGYTNGTNATHAARAGY CARATGGAYYTNGTNGARACNGCNAAYATHTGGAARCARAARCAYCAYGTNATGACNTAY TTYAARGAYAAYGTNAGYCCNAARCCNACNGAYTTYYTNAGYAARTTYTAYGAYGGNCAR GARGAYYTNAGYGARTCNTCNYTNGARTGYYTNYTNGARCARYTNATHCARMGNGGNGTN GTNAARAARGCNATHGTNATGGAYYTNGARGGNMGNATHATHGCNMGNAGYMGNCAYCAY ATHAAYAAYMGNYTNGCNTGYTTYTAYGAYAGYYTNYTNGGNCAYTAYACNGGNYTNATG AARATHACNGAYCARGAYGAYGTNTAYACNTGYTTYAARTGYCCNTCNACNGCNATGYTN GTNGCNAAYTCNAARAARTGGGTNTCNGTNGCN---------------GTNATGCAYGCN AGYGAYAAYYTNTAYAARMGNATG---------------TAYAARGAYAAYCARATGGAY CARGARTTYGAYCAYAARGTNAARAARATHTCNGAYAARTTYTCNGARACNATHAAYACN ATHGCNAAYGARCCNTCNYTNGCNTTYTTYMGNATHCARGARCAYGTNMGNAARACNYTN CCNCARYTNGTNGAYACNAARCAYGARGTNGARGGNYTNCARTCNAARGTNCARGGNTCN TGYTTYGAYACNGAYTAYGCNATHAAYGCNGTNAARGCNATGCARAGYAGYGCNATHCAY TTYGARAAYATHCARGAYYTNYTNAARAAYGCNATGTAYATGAARCARCARATHTCNTAY GARGARAAYAARMGNAARCARGAYMGNAGYACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARMGNATHYTNAARMGN YTNACNGAYGCNCAYGAYAAYTAYYTNGTNCCNCAYTTYACNGAYTAYYTNCCNCARGAY GTNGARCARCARCARMGNGAYCAYTAYGARGCNTGYAAYYTNMGNAARCARATGTTYGGN GGNATHAARMGNYTNCCNGAYCAYGARTAYGAYYTNGTNTAYAARGARACNGGNYTNGAY GTNGAYGGNMGNGCNAAYCAYATGAARGAYTTYGCNAARGCNATGGARGAYACNATHCAR GCNATGGTNTCNTTYGCNACNGTNATHCCNGGNTTYTCNATHYTNCCNAARGARYTNAAR ATHAAYYTNATHMGNTAYTCNMGNCARGARTTYTGYTTYYTNACNYTNTAYAARTAYGTN AAYAGYGARYTNAARGTNTAYAARGGNGTNTCNGGNTGYTGGGARTGYTCNYTNGARATG GARGAYTCNGARTTYMGNAARAGYYTNGAYAARGTNATGYTNTTYYTNGCNAARTTYCAR MGNYTNCAYATGCCNMGNGARGTNGAYATHYTNYTNAARGCNYTNAGYATHATHGCNCCN GAYMGNACNCARCAYATGAGYAAYAGYAARYTNGCNACNGCNATHTAYACNAARYTNGTN AAYYTNYTNATHTAYYTNYTNAARCARCAYGTNGAYAAYCCNATGYTNTAYTTYGCNAAR YTNATHGAYATHYTNATHGARTGYMGNACNAARGARGARGARYTNACNGAYYTNTTYAAR AARCAYCARYTNATHMGNTAYATHCCNYTNCARGAYAARCCNTTYYTNCAYYTNATGTTY TCNGGNATGTAYTCNGGNGGNATHCCNGTNACNAAYTCNATGTTYGCNTGYYTNAARYTN GARGAYGARATGGARGARGARAARAARAGYAARMGNMGNMGNAAYCARCARAAYACNTCN ACNGCNAAYAARAARAARGAYGAYAARMGNAARAARAAYGCNAAYGARAGYAARCARYTN CARCARYTNGCNTTYGGNAARCCNGCNAGYMGNAARAARTCNGGNAARAAYTCNAAYACN AAYAAYGCNMGNGCNCARGARCARAARCARAAYTGGGAYGARTGGAARGARCAYGAYAAR GARGTNGTNGARGAYCARTAYAARAAYGAYYTNGARAARGCNATHATGGCNAGYCARYTN CARYTNGARCARGAYAARTCNGTNCARAAYGAYAARAARACNGTNGCNGAYGCNGGNGAR GARYTNCCNAARACNMGNGARGARMGNAARAARAARAARCARAARGAYAARGCNAARCCN ATGTCNYTNGARGARTTYAARCARYTNCARCCNGCNGCNCCNAARCAYTCNGAYGAYTCN GAYGARGGNGARCCNGCNCCN------------CCNCCNATHCAYTAYMGNGTNCCNACN GGNGARCARGAYGAYAARTTYTTYAAYAAYGTNCAYGAYGARGCNAARCARATHYTNMGN CARGAYMGNATGCARGARGARTAYMGNAARACNTAYGCNGTNGAYAAYGCNGTNGTNGCN AARYTNAARAAYGAYATHGARATHMGNGAYAARACNGTNGCNGARYTNAARCARCARGTN GARCARATGCARGCNGARATGAARCARGTNAARCAYMGNAAYAARCARYTNTGYGTNATH YTNGCNCARGGNGARATGAARGAYAARGCNCARGTNYTNYTNCARGTNGAYGAYYTNAAY AAYGTNAARGAYGARYTNACNGARCARGTNACNTCNYTNACNGTNGARYTNGARAARGAR AARTCNAARAAYMGNGCNYTNAARGCNGARTCNGAYAARYTNAARGCNGGNAARCAYGGN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MGNTCNACNAGY GCNTCNAGYYTNTAYTGGAGYTGYGGNTAYTGYGAYTTYCARAGYAGYAGYCARGCNGAR ATHAARGARCAYTCNAAYMGNACNCAYCCNGGNAARCCNCAYMGNTAYGTNGCNYTNATH AARAAYATGAAYCCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGTAYCARACNGTNGGNCAYCAYGCNATHGAY YTNTAYGCNGAYGCNATGGAYYTNCCNYTNTAYGTNGCNACNATHAARGGNTCNAGYYTN TCNATHGGNMGNGAYTAYGTNCCNTGYGAYGGNGAYGARGTNGARGAYYTNTAYGARYTN YTNTCNCARATHAARACNGARMGNGGNATHGARGGNGTNAGYGTNGGNGCNATHYTNTCN GAYTAYCARMGNGTNMGNGTNGARAAYGTNTGYCARMGNYTNGGNYTNAARTGYYTNGCN TAYYTNTGGMGNMGNAAYCARGARGARYTNYTNMGNGARATGATHGCNTGYGAYYTNAAR GCNATHATHATHAARGTNGCNGCNYTNGGNYTNYTNCCNGAYAARCAYYTNGGNATGGAR YTNAARGAYATHTTYCCNCAYATGATHAARATGMGNGARAARTTYGGNYTNAAYGARTGY GGNGARGGNGGNGARTAYGARACNTTYGTNTTYGAYTGYCCNYTNTTYAARAARTCNATH YTNATHGARAAYAARGARYTNGTNATHCAYTCNGAYGAYGCNTTYGCNCCNGTNGGNTAY YTNAAYYTNAARAAYTGYTGYYTNATHGAYAARCCNGGNTTYGAYGTNACNTCNGTNCAY GARAARATHGCNCARYTNCCNYTNTCNACNACNGCNAARTGGYTNTCNACNCAYATHACN ---------ACNACNGARTCNYTNCAYACNGARAAYACNYTNAGYCARGCNGAYGCNCCN AGYCARGARATHGCNYTNGCNGTNCARGARTCNAARCCNGTNTTYAAYACNGAYGGNTCN MGNTTYCAYGTNTCNGGNYTNAARGCNYTNMGNACNGARACNACNGAYGTNGCNGTNGCN ACNACNTCNGCNATGGARGCNYTNAARGGNGGNATHGARAAYATGGGNTTYCARATGTCN GAYATGGTNTCNGTNTCNYTNTAYGTNGGNGAYATGTCNAAYTAYACNTCNATHAAYTCN GTNTAYAARAAYTAYTTYACNGTNAAYCCNCCNACNMGNATHTGYYTNAARYTNCCNYTN CCNTCNAAYGTNYTNTTYCARYTNGAYTGYCARGGNATHMGNAGYGAYGARAAYGARMGN AARACNATGTAYGTNCARAGYYTNTCNYTNTGGGCNCCNGCNAAYYTNGGNCCNTTYAGY CARACNATHAARGARCAYCARGARYTNTAYGTNTCNGGNACNACNGCNATHGTNCCNTCN ACNYTNAARYTNATHCCNGCNGGNATHGARGTNCARACNAARGTNGCNYTNATHCAYYTN YTNGARAARYTNGTNGCNGTNTGGCCNGCNTGYACNYTNTCNCAYTGYCCNYTNYTNTAY TGYTTYGTNAAYAARMGNCARCAYATHTTYGCNGCNMGNMGNTCNTTYGARAAYATGATH CARGARGGNGGNGAYYTNATH---------GAYYTNCAYCCNYTNGTNCARTAYTGYGTN ATHCCNGGNATGCCNCARGGNGCNCARGTNGARTGGCARACNTGYGCNTGGGCNYTNGAR ACNAARGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNGARAARMGNTTYMGNATGTCNGARGARGARAAYGCNTCNATGMGNMGNAARATG GARYTNGTNAARAAYGARTTYGARACNCARAGYCARYTNGCNGARGAYGAYYTNAAYMGN GTNTGYMGNYTNGARAGYCARYTNAGYGGNGCNCARATGGARYTNGARAARYTNGARAAR CARCARGTNAAYYTNATHCAYGARATHGCNATHGARATHGAYGCNYTNGTNGARACNGCN TCNGTNGAYGCNACNAGYMGNTGYCARCCNATHAAYGGNYTNAARAAYYTNGCNAGYGTN MGNTCNGGNATHCCNAAYCAYYTNYTNACNGARATHAARAAYAARYTNAARTGGYTNMGN TCNGARTTYMGNGARMGNYTNGCNMGNGARMGNMGNYTNMGNGGNGARTTYMGNACNGCN YTNTCNTCNTCNGARGTNGAYMGNCARTTY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GGNGARMGNGTNGCNGGNGAYYTNTTYGARYTNTCNGTNCARATGGARGCNGARAARCCN MGNYTNGARCARTTYGAYGCNTGGGGNAAYMGNGTNGAYAARYTNATHACNTCNAGYGCN TGGCARNNNATGAARGARGTNTCNGCNGTNGARGGNYTNGTNGCNTCNGGNTAYGARMGN AARTTYGGNGARTGGAGYMGNYTNTAYCARTTYAGYAARTTYTAYYTNTTYGARCCNTCN GCNGGNYTNTAYACNTGYCCNYTNGCNATGACNAAYGGNGCNGCNMGNATHYTNGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYYTNGTNGTNGGNYTNGGNAAYCAY CCNTAYCCNAARACNMGNCAYAGYATHGGNYTNATGGCNGTNGAYGTNYTNGCNCARCAR YTNTCNTCNACNTGGGARAARYTNCCNGGNTGYCAYGGNGGNYTNYTNAGYCARGCNACN ATHACNGAYCARACNGTNGCNGTNGCNAAYGTNTAYYTNTTYAARCCNAARTCNYTNATG AAYATHTGYGGNAGYAAYGTNGCNAARACNGCNAARTAYYTNGGNGTNGAYGTNGAYMGN GTNTAYYTNATHCAYGAYGARYTNGAYATGGCNACNGGNAARGCNAAYATHAARTAYGGN GGNAGYGCNAAYGGNCAYAAYGGNGTNYTNTCNTGYATHTCNTGYYTNAARTCN------ ---------------AAYGCNYTNTGGCCNAARGAY------GAYTCNCARAARYTNMGN MGNYTNMGNATHGGNATHGGNMGNCCNTCNTCNAARTCNGARATHGTNGCNTAYGTNYTN GGNTCNTTYMGNGAYGAYGARMGNGGNATHATHTAYTCNGGNATHGGNAARGGNYTNGAY ACNYTNATGAARCAYATHAARGARMGNATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGATHGTNAGYTCNMGNTCNGGNGAY AGYTAYGTNACNGCNTCNGAYAAYACNGARGTNGTNCARGAYAARYTNAARTTYGAYATG GAYAARYTNCARACNMGNCCNATHYTNGGNCARCCNTCNGCNGAYACNCAYGCNYTNMGN GAYGAYGAYGCNTCNACNGAYMGNGCNYTNAAYACNMGNTAYGTNGARTCNCCNATHTAY ATHAAYTGYGARGAYGAYAARGARAAYGCNCCNTCNACNAARGGNGGNAAYAARTCNCAR AAYCCNAGYMGNYTNACNCCNGTNMGNGARGGNGCNGGNAARACNTTYGTNAARTCNAAR CCNTAYYTNACNYTNGCNGAYATHCARGCNAAYGARYTNAAYGGNTCNGAYGAYGAYGTN ATGTCNGTNTCNATGATGTCNGTNGCNTCNAGYGCNTCNYTNGCNTCNCARGTNYTNGAR MGNGCNAARAARMGNCARAARGARTTYTGGGGNAARGGNGAYTTYAARTAYTTYGGNTAY GGNAGYAAYATGYTNACNGARMGNATHCAYATHCARAAYCCNTCNGCNMGNTAYGTNGGN AAYGGNACNYTNAARAGYTAYAGYTTYGGNTTYYTNACNCCNGTNACNYTNCCNCCNAAR TTY---GGNGCNATHGCNACNATHMGNCCNGCNTCNGCNGAYMGNGTNATGGGNATHGTN TGGGARATHGAYTCNGAYCARATHGAYTCNYTNGAYTCNCARGARAGYAAYTAYAARCCN ATHCARGTNGAYGTNATHYTNGAYGAYGGNACNACNTGYAARTGYMGNACNTAYGARYTN AARGARAARGTNGARTCNGAYGAYAARMGNCCNCAYCCNTTYTAYAARAARATHTGYGTN GARGGNGCNMGNMGNCAYGGNGTNTCNAGYGAYTAYATHAARTTYYTNGARAGYTTYGAR GAYAGYGGN--------------------------------------------------- ---AARCARTGGYTNCAYCCNTCNAAYGCNYTNACNAARGGNCAYATHYTNTAYACNGTN AARTAYYTNGGNGARTGYAARGTNGARCARCCNAARGGNACNGAYGTNGTNAARTCNGCN ATHACNAARATGAARTTYAAYAARCAYATHAARMGNGCNGARGGNCARAARCCNCCNAAR GTNGARYTNACNATHTCNGCNGAYGCNGTNAARATHYTNGAYCCNAARAAYAARYTNATH YTNCAYCARTAYCCNYTNCAYMGNATHTCNTAYTGYGCNGAYGAYAARTCNGAYAARMGN ATGTTYACNTTYATHGGNAARGCNGCNGAYAAYAAYGAYCAYTTYTGYTAYGTNTTYGAY AGYGARAARTGYGCNGARGARATHACNYTNACNATHGGNCARGCNTTYGARYTNGCNTAY AARMGNTTYATHGARGCNTCNACNCARGAYAAYGAYATHMGNAARCARTTYYTNGTNYTN CARCARAARGTNAAYAARYTNCARTAYGARAAYGAYGCNYTNAARAARMGNYTNGCNGAY GTNGARAARYTNAARGAYMGNTCNGAYGTNGARCARTAYAARATHAAYAAYGARATHAAY GAYATHACNYTNGTNAARYTNAAYYTNMGNGARAGYTCNACNGAYGARGAYGAYAGYGTN AARAGYGARCCNAAYAAYCAR------GGNAAYGTNGTNGGNMGNMGNYTNGARAAYYTN GTNTTYTCNGAYGAYCAYACNAARACN---------------------CAYACNAAYGGN AAYCAYACNCCNTCNTCNTTYAGYAAYTCNAAYTCNTCNACNCCNATHYTNAGYCCNCCN CCNCCNAAYTCNMGNCCNTCNMGNAAYTCN------GTNAAYGGNACNAAYMGNATGAAY TCNYTNAAYAGYGCNAAYAAYAAYAAYACNGGNTTYGGNAGYCARTCNAAYAGYACN--- ---------GAYYTNTTYGGNATGGCNGARTTYAAYCCNCCNCARCAR---TCNCARCAR GARYTNATHGAYATHMGNGAYGGNTTYACNMGNGGNATHTCNTTYGGNCARGAYGAYTTY AAYATHGAYGAYYTNGAYCCNYTNAAYCARAAR---ATGGGNAARTCNAAYMGNAAYMGN AARACNMGNTTYTCNTGYGGNCAYTTYGGNTCNAARAAYAARTCNGARYTNTGYCCNAAR TGYAARAARCCNGCNCCNTCNTCNAARMGNTCNCCNGCNCCNTCNTCNAARMGNAARMGN AAYAARAGYGTNCARGGNGGNGGNATGGAYTCNAARCAYTTYTCNTCNMGNTCNACNACN GAYAAYYTNCCNAGYTCNYTNAGYACNCCNGGNGARMGNGCNGGNYTNACNTCNGCNACN CCNGCNAAYGTNGAYACNTCNGTNGCNACNTCNTCNAAYAAY---CCNAAYTCNYTNTCN CCNCAYYTNCCNACNACNTGYGGNACNACNTCNCAYGCNACNAAYACNGTNACNGCNGTN TCNGARGCNAAR---------ACNGAYACNAAYMGNYTNCCNCCNGAYACNACNGAYTCN CARTCNTCNYTNTCNAGYGAYAARYTNTAYGAYCCNAARAAYGAYCCNAAYAAYTTYTGY TCNTCNTCNAAYTCNTGY---------------------TCNAGYYTNCCNGAYYTNTCN GCNGTNATHTCNTCNACN------------AAYGTNCARACNGAYAAYYTNYTNGTNACN GAYYTNAARGCNAAYGGNYTNTCNAGYACNGAYAGYGTNAGYYTNTCNTCNCCNTCNACN YTNTGYAAYAAYAAYGGNCARACNGTNTCNYTNGAYTCNGCNAAYAGYGCNGGNATGGGN AGYGTNTCNAAYAAYGTNGAYAAYATHTCNTCNATHTCNGARMGNYTNGARGAY------ GGNTGYAARGAYAAYGGNTCNCCNACNCARAAYAARCCNCCNTCNGGNTCNAAYATHYTN AAYGAYGCNTCNATHGCNGAYGAYTCNCCNCARTCNCCN------MGNGGNACNAARMGN ACNCAYGCNGARGTNGARGAYACNATHGARGTNTCNGAYTCNCCNAARCCNTCNCCNCAR AARAAYAARAARMGNTGYTAYGTNTGYAGYAGYAARYTNGARYTNGCNCARMGNACNATH GGNAARTGYMGNTGYGAYCAYGTNTTYTGYCCNACNCAYMGNYTNCCNGARYTNCAYGAY TGYGTNTTYAAYCAYAARGARGAYGGNMGNMGNGARGCNMGNGARAARATGGTNAARCCN ACNMGNCAYATGGGNACNTCNTTYMGNMGNGAYYTNTGYGARAARGARAARGAYGAYTAY GTNGGNGAYGCNATHCARAARGARGTNMGNTAYGGNMGNGGNCCNTAYGTNATHAAYGGN ATHCCNATHGCNCCNGGNATHCARGGNTGYTGYAAYAARGAYCCNTGYTTYTGYMGNTCN GAYGTNATHTTYTAYGAYGGNATHGCNTAYGAYCARAARCCNTTYATHGARGGNGGNYTN MGNACNMGNGCNGGNAAYGTNATGTTYTAYGARGGNAARATGGCNGGNCCNTTYAAYCCN GGNAARTCNCCNYTNATHTTYGGNCCNAAYAARAAYMGNGAYAARCCNCCNCARMGNAAY TGYTTYGARACNGTNAARACNGGNCAYGGNTAYAAYMGNTGYTGYACNACNTCNATHTAY GGNGAYAARGTNGCNCCNTAYCAYAAYACNCAYAARYTNGCNTAYACNMGNYTNGGNYTN CCNCAYGGNAAYACNGTNGGNTAYTTYMGNTTYAARCCNAARMGNATHTGYTAYGAYMGN GAYACNCCNGTNCARMGNTAYGARGAYTGYTGYGAYTGYCARCCNAAYGCNTAYGAYGCN AGYCARTAYATHAAYGAYGARTGYCCNGGNAARMGNTGYTGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATHACNATGTCNGGNATHACNTGYYTNGCNTGYAAYATHAGYTTYGAYGAY GCNGAYYTNGGNMGNATHCAYTAYMGNGCNGAYTGGCAYMGNTAYAAYYTNAARMGNAAR GTNGCNGGNTTYGCNCCNATHACNYTNGARAARTTYGARGARMGN---------CARMGN GCNCARGARCARTCNGARACNGCNACNGTNCAYGARACNTGYYTNTGYAARCCNTGYAAY AARTCNTTYAGYACNTCNAAYGCNTAYGAYAAYCAYYTNCARTCNAARAARCAYAARGAY GTNATHTCNGGNGTNGTNAARTCNAARAARAARGGNAARAARAARAAYAARYTNTCNACN GCNAGYACNGCNTCNGGNAGYGCNCARAARGAYGARAARGAYGAYGARTGGATGTCNGAY GARGAYGARAAYTCNGAYGCNGARTCNTGGGAYAGYTAYGAYGGNAAYATHYTNGGNYTN GARGARTGYYTNTTYTGYTCNCAYATHAGYCARTCNYTNGARGAYAAYYTNTCNCAYATG ACNACNGAYCAYGGNTTYTTYATHCCNGAYGCNGAYTAYATHTGYGAYYTNGAYGGNYTN ATHGCNTAYYTNGAYGARAARGTNGGNGCNGGNCAYATGTGYYTNTGGTGYAAYGARACN GGNAARMGNTTYCAYAAYACNAARGAYGTNCARMGNCAYATGATGGAYAARGGNCAYTGY AARYTNYTNCAYATHCCNGARACNATHTAYGARTTYGCNGAYTAYTAYGAYTAYTCNAAR AGYTAYCCN---------AGYGCNGAYGGNAAYACNGAYCCNTCN---GAYCCNGTNGAY ATHATGGARYTNGAYGGNGAYGGNTAYTCNYTNACNYTNCCNTCNGGNGCNGTNATHGGN CAYMGNTCNYTNGTNCAYTAYTAYMGNCARAAYYTNGTNCCNCARATHGGNGARMGNACN MGNGCNTTYYTNCCNAARATGYTNGCNCARTAYAARTCNYTNGGNTGGACNGGNGCNACN GGNACNGTNGTNGCNCARMGNGCNAARGAYYTNCARTAYATGCARMGNGTNMGNAAYCAR CAYTAYATGMGNGTNGGNGTNAARGCNAAYAARYTNMGNYTNMGNYTNMGNCARCARAAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNGTNGTN TCNTTYYTNAARGARTAYGTNAARYTNAARMGNATHGCNGARATGGARATHGARGTNGAR GAR---GARGAYACNGARGGNACN---------AARACNYTNCARGARATHGAYAARAAY YTNAAYAARYTN---AARGARAAYMGNGARCARGARGARAAYGARGGNGGNYTNGTNGAR GARGARGARAAR------------------------AARAAYCCNCCNCARTAYGTNCAR GTNGTNAARGARGTNYTNGCNMGNATHAARAAYYTNYTNACNTCNCARGAYGCNMGNATH MGNGTNCARGCNYTNGARATHGTNGCNCARAGYTGYCARGAYYTNGCNGAYCAYGARMGN GARYTNYTNCCNCARYTNCAYCARATHTGGCCNAGYTTYTAYCCNMGNTTYCAYAGYGAR GARAARTTYGTNGTNATHAARGCNYTNCARACNYTNCARGTNATGTCNAAYGTNGGNGGN AGYTTYGTNCARCARMGNGTNATGAARGAYGTNATHCCNAGYYTNTCNCARTTYATGGAR AARCARGCNAARATHAGYGGNAAYAGYTCNGGNGTNTAYYTNCAYACNCCNAGYTTYAAR YTNCARGTNGCNATHYTNAAYATHTCNGGNCARYTNTCNGARAARYTNGARYTNAARGAR MGNAAYYTNGAYYTNGTNGCNAARATGTGYYTNCCNTAYYTNAGYTGYCARCARCCNYTN CARYTNCARACNTCNTGYATHAARACNTTYGCNTCNTTYATHCAYYTNGAYCCNGAYGCN ATGTGGYTNCCNYTNTGYMGNYTNTAYTGYCCNTGGGARTAYAARATHCCNAGYCCNAAY TTYAARCCNYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CARCARGCN TAYYTNGCNGCNATGAAYYTNGARMGNCAYTCNGCNTTYCCNCAY---------TCNTCN TCNCARAAYCARGAYGCNATGACNYTNCCNAARTTYAARCAYAARTAYATHGCNCAYACN CARYTNGCNCCNMGNMGNCCNATHGGNCARTTYAARTTYTTYYTNYTNGGNMGNACNGAR MGNCARTCNGTNTTYAAYAARGGNACNCARACNMGNGAYGARGCNGTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNMGNGCNGGNMGNGTNMGNAARAARTCNGCNAARGTN YTNGARATGGARGARTTYGARCARGCNGARAARACNACNACNACNAARAARGGNAARACN CCNAARGTNGTNTCNGAYAGYATGCCNAAYAARAARCCNAARCCNGTNGTNGARGTNACN CCNYTNTCNMGNAARACNAARAARAARTCNATHGAYAGYAGYAARTCNGTNCCNGCNGAR YTNACNYTNMGNCCNACNYTNACNCAYGTNGCNYTNCARCARCARGAYATHAARGARAAY TCNGARAGYGTNATHAARAAYYTNYTNAGYGGNCCNYTNGCNGGNTCNACNCCNACNYTN TCNACN---------------------------GGNTTYATHGARGCNCCNACNGTNACN CCNATHCCNTCNAARAARTCNAGYAARAARATHAARTTYGARGAYGGNTCNACNTCNACN CCNAARTCNAARCAYAARGARAARAARATGAARATHGARATHATGTCNCCNTCNGARAAR CCNCCNGTNTCNAGYCCNCCNCCNCCNCCNCCNCCNCCNGCNGCNGGNATHAARATGAAR ATHGTNGGNGGNTCNAAYCCNATGATGGCNAARATHTCNYTN---GAYGTNCARGCNAAY GCNGAYGGNCARACNCCNGCNAARGGNAARAARGCNGCNGCNAARAARCARAARACN--- ---------------------------------------------CCNAARGAYTCNTCN AAYGARGARAGYAARAARGARGARAARAGYAARAARGTNTCNAARAARAARGARAARYTN ATHCARGAYGCNATHAAYGCNGCNCARCARGTNCCNGGNATHGCNTCN------CCNCCN ---CAYCARCCNTTYGGNGGNTCNGGNGTNTCNCCNCCNGTNACN---CARAARGCNAGY AARAARAARGARAARAAYCCNCCNGTNAARAARGARCCNGTNTCNYTNAAY--------- GAYTCNYTNGTN---ATGGAYTTYGARGTNGARGAYATGGARGARMGNGARGARGCNACN YTNGTNATHGCNGARACNGARAARAAR---AARAARGCNGGNAARAARACNAARAGYCCN ------------AARGARCCNAARTCNAARGARGARCARAARACNAARAARGTNCCNAAR MGNGCNCCNACNGCNTAYATGYTNTTYTGYAAYACNCAYMGNCCNGGNATHGTNGCNGCN AAYCCNGGNATHGARTTYGCNGCNATHAGYMGNAARYTNGGNGARYTNTGGCARACNCAR TCNAGYAARCARAARYTNYTNTGGMGNMGNAARGCNCARMGNMGNATGAAYAARACNAAY YTNATHTCNACNGGNAARAAY---GGNAARGARTCNCARGGNGGNTCNGCNAAYTTYATH ACNTCNTCNCAYAGYAAYGCNAARTCNACNAAYCARAARYTNGCNYTNATGYTNCARAAR AGYMGNCCNGTNGTNGCNGAYGARGGNCCNYTNAGYCCNACNAARACNTTYAGYATHGAR CCNYTNGAYGTNGCNGCNCAYYTNAARYTNYTNGGNGARTCNYTNAGYATHATHGGNATG MGNYTNCARGARCAYAARGGNATGATHGCNGTNCARGGNAGYYTNTCNGTNYTNYTNGAY TCNYTNYTNTGYGCNTGYGGNCCNYTNYTNTGYYTNACNCARCARGTNCCNGGNATGGAY GGNTGYTCNCCNTCNGTNCAYGCNCARACNYTNGAYAGYGTNGCNTAYGTNATGCCNGGN YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GCNTAYCCNCCNCCNCCNCCNGCNGGNTTYTAYGGNGGNGCNCCNCCN CARGCNTAYGGNAAY------------------CCNCCNGCNGGNTAYGGNCCNCCNCCN CCNGCNGGNTAYGGNCCNCCNCCNCCN---GGNTAYGGNGGNGCNCCNCCNCCNGGNTAY GGNCCNACNCARCCNGGNTAYGGNGCNGCNCCNTAYCCNCARCARCARTAYCCNGGNCAR CCN------------CARTAYCARCAYGGNCARCCNCARCARGTNGTNTAYATHMGNGAR GARMGNMGN---MGNGAYAARGAYGAYTCNGCNGARACNTGYTGYYTNATHGGNYTNTGY AGYGCNYTNYTNTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TAYAAYTAYGAYAARTAYGGNATGCAYTTYAGYTCN CARCCNTCNYTNGCNMGNACNGGNAGYMGNGAYGGNAARTTYGCNCAYGGNMGNYTNAAY CARATGAAYGGNAAYCAYYTNYTNAAYGGNCCNCAYGAYYTNTTYGARCCNTAYTAYCAR CARAGYTCNAARMGNGGNTAYCAYGAYMGNGAYAGYCAYMGNGAYCARMGNAAYGGNGAY GGNAARGAYAARGAYAARCAYTCNGGNAARGGNMGNCCNTTYGCNGAYGAYTTYCCNTCN YTNAAYGGNTCNGGNGARAAYYTNTCNGAYTCNAARACNAARCCNGCNTCNGGNGTNTGG GARAAYCCNCCNAAR---TCNACNAAYAARATHGAYGARACNTCNGAYTCNTCNAARGTN AAYTCNCCNGGNATHTAYAARGCNYTNGTNCCNAGYAARAGYGTNCARAAYAARAARCCN GCNAARGAYGCNTCNMGNGTNAAYGGNAAYGTNMGNGARATHTCNCCNYTNAGYCCNTCN AAYAARCCNAGY---AARGARGGNTCNMGNTAYAGYCCNACNCCNGAYYTNGCNATHGTN ACNCARCCNAARAARYTNGGNGAYAARAARAGYGAYTTYYTNMGNGCNATHMGNAAYGAR AGYTCNATHMGNAAYGGNGAYGTNTGYCARAAYCARAAYCARAAYATGATHAARAARCAR GARAARCARYTNCAYGGN------------------GAYGAYAARAAYGAYAAYYTNATH TGYAAYMGNYTNAAYGGNGAYCAR---------------GTNGTNGAYTCNAAYGARAAY YTNYTNAGYYTNAARAARGAR---TGYTTYAAYGGNGAYAAYGGNGAYTCNYTNATHAAY CAYGTNGAYCAYATHACNYTNTCNGGNGARGARGARGARMGNMGNYTNYTNYTNTCNATG GGNTGGGARGARGARGAYAAYACNGARTAYGTNATHACNGARGAYGARATHAARGARTTY ---------YTNCARAAYCAYTGYCAYGGNCARAARAAYGGNYTNAARTCNTCNYTNMGN AGYGCNYTNGAYMGNAARTTYGGNGCNGARTCNGCN------YTNAAYGGNATHCCNTCN GAYGARGARAARACNGAYAARGTNYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYGGNMGNTAYCCNMGNGARTAYAAYCCNAARGTNCAYGGN CCNTAYYTNCCNGGNMGNTTYTAYGGNAARCCNGAYACNCCNTTYGGNCARGTNAARYTN GGNGAYATGGGNGCNTGGTTYGGNMGNMGNAAYAARACNCCNACNTCNATGTGGGAYGCN GTNCAYMGNGGNTAYTGGMGNTGGGCNACNAARAAYYTNCAYGTNMGNCAYAGYGGNTTY GTNCCNTAYGGNCARGCNGCNATGYTNATGTCNATHGTNTTYTTYGGNYTNYTNTAYAAR GARMGNAGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARCARAAYTAYAGYCARGCNACNAAYCARATHAGYCAYATGGARACNACNGTN AAYGCNYTNCARGAYAARYTNACNGARAGYMGNAGYMGNGARATHGAYAARGARCARTCN ATHGARACNYTNMGNTCNGARYTNGARGGNYTNGAYACNGTNTAYTCNCARAGYAARGAR GARYTNAGYAARTGYGARGAYATGATHCAYCARYTNACNTCNGARYTNGAYTCNGCNCAR AARGARATHGGNTCNGCNCAYAARMGNGTNAARGAYYTNGARGAYAGYAGYMGNGAYYTN MGNGARCARYTNCARAAYGCNCARCAYCARGCNYTNCARAAYGAYGARMGNGCNCAYAAY YTNGARAAYAARYTNYTNTCNTAYCARGGNGARCAYAGYCAYTCNGAYMGNGARTTYYTN CARMGNGARGARCARATHAAYTCNYTNGARTAYCAYYTNGARGARGTNMGNGGNGAYATH CARAGYMGNGARTCNACNATHGARCARYTNAARAAYGAYYTNTCNGTNACNCARACNGAY YTNCARCARGCNGTNGAYGAYAARAGYACNGCNATGAARGARATHGAYMGNYTNGARCAR CAYAGYGARCARYTNCARYTNAAYYTNACNTCNGCNCAYCARMGNCAYAARAGYGARACN TGYMGNTTYGARGARCARATHACNTCNYTNGARMGNCARATGTCNGARGGNCARACNGCN ATGCAYGCNTCNGARTGYGARGTNAAYAAYAARGARGARCARATHAARMGNAAYGARGCN GARATHGCNACNTGYMGNGAYGAYATHMGNGCNAARGTNGARGARATHGARMGNYTNGAR MGNTCNYTNCAYGARACNAARCAYGARYTNAAYCARACNGTNGGNCARTGYAARCAYYTN GARGCNTCNATHAAYGAYATGAARACNGARGGNGARATHATGMGNAARGAYGTNGCNGAY TCNMGNAAYCARTAYAARGAYTGYGCNCARGARYTNGCNCAYCAYGARGARAARYTNAAY YTNATGGARCAYAGYYTNCARTCNACNCARGAYCARYTNAGYCARMGNGTNACNGARATH GTNMGNCAYGARCARAAYACNMGNAARYTNCARGCNGARYTNAARGCNACNAARGARMGN GCNGCNTCNTAYGARGAYGARATGGARGAYCARAARAAYATGATHGAYAARYTNMGNAAR GAYYTNGTNYTNTCNAARGARGARTTYCAYTCNTCNGTNCARGARGGNATHGCNTAYAAR CARCARGCNCAYAARAAYGARYTNGARYTNTCNGGNAGYMGNGARCARGARAARATGYTN TCNGAYCARGTNGARCARCARGARCARATHYTNAAYCARYTNCARACNGARYTNMGNGCN GARMGNGARMGNCAYGGNGAYACNGTNAARCARYTNTCNGCNTCNAARAARAGYGGNYTN GAYYTNCARGCNGAYTTYGARTCNATGCARAARCARGCNMGNGARYTNCARGAYMGNGTN AARGCNMGNGARGARCARATGATHMGNYTNMGNCARGARATHGAYAAYYTNCAYCARAAR AAYMGNGARGCNAAYGARTCNYTNGCNGGNAARGAYGGNCARYTNMGNYTNGCNGARATG AAYYTNCARACNGCNGGNAARCARGCNMGNCAYCAYGARCARGARATHGGNMGNTAYGAR GAYACNYTNGGNCARYTNCARACNGAYYTNGARAARYTNCARGARCARTAYAARCARACN GCNTCNAAYYTNATGGARGCNGAYAGYAARGTNCAYGARYTNAARGTNCARYTNACNACN GTNCAYGGNAAYCAYAARGARGCNATGGARCARYTNACNGAYAARGCNMGNCARYTNGCN TCNATHAARACNGAYGCNGCNAARATGGGNCARCARAAYAAYTCNATGAARGARGARATH ATGYTNTAYGAYGARAARGTNMGNAARYTNCARCARGARTTYMGNAARTCNCARGARATH AAYAARGCNACNGAYGARGARYTNCARCAYYTNGARGARMGNTAYACNAGYYTNCARGTN GAYYTNGTNACNAGYCARGARAARCARAARCAYTCNYTNCARGARYTNTCNTCNAARGAR GARGARACNGTNGTNACNAARGTNGARYTNAGYTCNATHCARGARMGNTAYAARTCNYTN AAYGAYGARGTNACNAARYTNACNGGNGARYTNGARYTNACNAARCARAAYTAYMGNAGY GCNACNGARGARATHTCNGGNYTNMGNATHGCNYTNGARGARTCNMGNGCNAAYGGNGAY MGNYTNCAYMGNGARAGYGARYTNGTNGTNCAYAAYGTNAAYACNTGGGTNCARGARCAR AARATGGCNAAYGARAARYTNGGNAAYAARATHMGNGARCARAGYAARTCNATHATGGCN YTNACNTCNGARAARGARGGNYTNYTNGARCARGTNACNAARYTNCARAARCAYTAYAGY AARACNMGNACNGARYTNGARGAYAARACNGTNGARTCNGARAARYTNMGNGCNYTNCAR TCNCAYTCNACNCARCARCARATHATHYTNAAYCARYTNAARGGNMGNYTNGARGARCAY GARYTNGAYAARGAYCARGAYYTNAARTCNAARYTNGCNACNATHGARGAYYTNCAYTAY MGNYTNAARTCNAAYATHGAYAGYATHCAYCARYTNAAYCARCARYTNAGYACNYTNCAR AARGAYAAYATHMGNYTNMGNAGYGARYTNGAYMGNGARATHGCNACNMGNCCNACNYTN GARATGCARATG------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARGAYCARGGNGAYGAYGARTTYMGNAAR GTNYTNGCNATGYTNGARGGNATHGARTGYYTNAARMGNAGYGARCCNGCNGARACNGAR GCNATHMGNACNGTNATHGARGCNAAYCARYTNCARGARAARCARATHCCNTCNCAYTTY TTYAARYTNMGNGARGCNTTYGARGGNYTNYTNGGNCAYATGTCNYTNACNTCNYTNGTN MGNAGYATHCCNMGNATGGCNGARAARGGNYTNYTNGAYTCNAARTGYACNGAYGCNGAR AARGTNATHYTNMGNYTNAAYGAYACNGARAGYTAYAARAARGARAGYATHTCNCCNGTN ACNGTNTTYATHTCNATGMGNAARTAY------------------------AGYCCNACN GAYYTNATHGTNMGNAARMGNACNMGNGGNCARMGNGAYMGNYTNMGNCARATGMGNCAY GAYAAYMGNMGNGTNACNGTNCARGGNYTNGCN---------AAYCAYCARACNTCNTCN GGNYTNTAYGAYGAYAGYYTNTCNGAYTAYGCNGAYCCNCCNMGNCCNGARGTNTCNGAR AAYYTNGTNTCNGCNTAYAARAAYATGACNAARGARGARYTNYTNMGNGTNGTNATHCAR ACNAARGCNCARATGATHMGNAARGAYCARTAYATHAARGAYYTNGARAAYTAYATHGAY GAYYTNYTNGTNMGNGTNATGGARACNACNCCNAARYTNCARACNMGNGTNYTNATGATH AGYAARYTNTGYATHCARYTNAARYTNAARYTNACNACNATHTTYMGNAARGTNGARGAR GAYTCNYTNYTNGTNTGYTGYCAYGTNTTYGTNGCNGARMGNYTNGTNGCNATHGCNACN MGNACNACNMGNMGNGARGCNCARAAYGARGCNTTYAARATHGCNMGNMGNACNYTNGCN GGNCARTCNGGNAARGARGTNYTNGAYACNTGYACNGTNATGACNCARCAYGAYYTNAAR GGNAGYGAYATHYTNGAYATHGTNTTYAARGGNTAYACNAARACNACNGARTCNAAYMGN TGYMGNYTNCAYMGNACNMGNAGYYTNGCNYTNGTNGTNACNATGMGNYTNGAYYTNTCN CARTAYGTNGARATHYTNCAYGAYTCNCCNACNCARAGYCARGGNMGNTAYMGNYTNYTN CCNGAYTGYGARMGNCCNTCNCAYAAYGAYGTNGTNGGNGARATHGCNGTNAAYGAYTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATHGCNGARMGNGTNTCNTTYYTN GARAARGARAARGARATGATHTAYMGNCARATHCARGAYCAR---CARCARCARCAYGTN TCNMGNCARCARCAYCARYTNCARMGNCAYMGNAAYTCNCAYTCNMGNMGNAARGARGAR YTNYTNGAYACNYTNMGNGAYYTNAARATHAARYTNGARGARCARGGNMGNMGNYTNCAR ---------------------------AARGGNATHYTNAARAGYTCNAAYAGYATHGAY CAYAGYAARAARGGNYTNGARTGGGAYGARATGAAYATHYTNGCNACNCAYCAYCCNCCN GAYAARGAYTAYGGNTTYATGAARGTNGAYGARCCNCCNACNCCNTAYAAYAAYGCNGCN ATHTCNGAYGCNGARGAYGAYGGNGGNTCNYTNAARAARAARGGNAGYTTYGAYGGNACN ACNAGYATHGAYCCNACNGAYYTNGCNTCNMGNYTNGCNGCNAARGGNGGNGARAARGAR CARAARTAYGCNGAYGAYGAYGAYGAYGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GAYATHGGNGAR ACNATHGCNCARMGNMGNMGNMGNGCNGGNATHTGYAARACNACNACNGGNCCNGCNCCN GARMGNMGNAGYACNATHAGYAGY---ATG---TCNAGYAGYTAYCARGTNACNMGNATG MGNAAYYTNTCNGGNGGNAGYAGYGGNAGYGCNGCNAGYGGNAGYAGYAAYGGNTCN--- ------YTNGAYAAYCARTAYTCN------CARGARAAYCCNATHTAYTAYTCNATGGAY ACNACNCCNTTYGCNAAYACNTCNCCNYTNCCNCARCAR---AGYGARGAYTCNATHTCN TCNTCNCAYCCNAARYTNGAYMGNAGYYTNAGYGAYACNGAYAGYGARMGN---AGYAAY GGN---------TCNCAYMGNTCNGTNAAYTCNAGYMGNTAYAARACNGARYTNTGYMGN CCNTTYGARGARAGYGGNTCNTGYAARTAYGGNGAYAARTGYCARTTYGCNCAYGGNGGN CAYGARYTNMGNAAYYTNTCNMGNCAYCCNAARTAYAARACNGARCCNTGYMGNACNTTY CAYACNATHGGNTTYTGYCCNTAYGGNCCNMGNTGYCAYTTYATHCAYGARGAYGARAGY AARGCNGAYAGYTGYGGNAAYTCNAAR--------------------------------- ------TCNAGYAGYGGNACNACNAGYCCNTCNYTNAGYCCNACNGGNAAYGAYAAY--- ---CAYGAYTTYTCNTAY---------TCNGAYTCNTCNATGGTNAAYAAR--------- ---------------TCNYTNTCNGTNAAYATHAAY---TAYGGNAAYGAYYTNAAYTCN YTNGARCAR------------CAR---TTYTCNTCNGCNYTNAAYYTNAAYGGNGTNGAR TCNTCNMGNGGNTCNTTYAAYAAY------------------------------------ ------------AAYGARGARTAYGAYATHTTYAGYTCNATHTCNGTNTTYAAYGCNGAY GARGTNAARGTNGAYAAYTCNCCNAAR------------TCNACNTCNTCNTAYTCNTCN CARTCNAGYCAYTCNTAYCARGGN---TTYGGNAGYAAYATHTCNCARTTYTGGTCNAGY ---------CAYCCNTCNCARAGYYTNGCNCCNGTNGAYACNTTYCAYCAYTCNCCNACN GGNTCNACNGGNTCN------------------------TCNTCNTCNATHTCNGAYAGY AGYGGNAGYACNGARAGYYTNGCNGGNTTY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGYTN MGNAAYATHTCNTCNGCNGCNTGYGCNYTNGCNGTNGGNGCNAARAARGAYACNGAYGGN TCNAAYGGNGAYTCNYTNGTNACNGCNAAYAARYTNTGYYTNGARAARTGYATHCCNAAR GTNCAYGCNACNAGYGAYAAYGTNTAYGTNGGNGAYMGNATHAARAARGCNGTNGGNTTY CCNCARYTNACNGCNTGYTGYAARCCNYTNMGNTAYAARGAYTTYATHATHTCNTAYGAY ACNAARAAYMGNATHCCNAAYTGGGTNTAYGARCAYYTNTAYTTYAGYAARYTNTTYAAR GAYGAYCCNTGYGAYAARMGNCCNYTNTGYTCNGARATHAAY---ACNGARAARCCNAAR TTYCAYCCNGAYTGYMGNATHCAYGGNTAYCAYMGNTCNGAYGTNAARGAYTAYTGYGAY TCNGAYTAYGARYTNGGNYTNATGGCNGAYCCNGCNAAYTAYCCNTAYGAYTGYGARGCN GCNGGNGARACNCARGTNATGACNAAYGTNGTNCCNATHGTNCCNGGNTTYAGYTGYGGN CCNTGGTTYGAYYTNCARTGYTAYATHMGNGAYACNYTNGTNAARGARCAYAARAGYGTN TAYGTNTGYTCNGGNCCNYTNTTYYTNCCNGAYCARCARCARTCNACNAARTCNATGAAR TTYGAYGTNYTNGGNGARGGNGARGTNTCNGTNCCNACNCAYTTYTTYAARGTNATHATH ATHGARACNYTNGAYGGNAAYYTNGARYTNGARTCNTAYATGATGCCNAAY--------- AARGARYTNGAYGAYTCNGARYTNGAYAARTAYYTNACNCCNYTNTGYAARATHGARCAY TAYTCNGGNYTNATHTTYTTYCCNGARMGNAARGTNTGYTTYACNAGYAAYAAYAARMGN MGNGGNGCNATGYTNCAYGCNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNGGNTCNTAYTGYAARAAY ATHYTNYTNAAYYTNACNGTNMGNYTNGARTCNAARATHGAYYTNTCNAARTGYAARYTN GCNAARGTNTAYGGNATHTCNAAYATHTTYATHTCNAAYGTNMGNTCNAARAAYAAYGAR TCNTCNGGNMGNATHGTNGARTCNACNAARGTNCARATHTCNTCNGTNCAYAGYGARAAR TTYCAYCARYTN------TCNYTNGAYATHAARAARYTNGAYYTNGCNGGNYTNAAYGTN GARYTNCARACNGCNAAYMGNYTNTAYMGNATHAAYAARYTNTCN---ACNAARATHTAY MGNCCNCARGGNATHYTNYTNCAYGGNCCNCCNGGNTGYGGNAARACNTCNTTYTCNAAR GTNYTNGCNAARCARAGYGGNGCNATHYTNTAYTCNGTNGAYAARTCNGAYYTNYTNACN TCNGAYTTYGGNAGYGGNGCNGTNAAYYTNMGNGARATHTTYAARACNGCNYTNAGYYTN YTNGARGARGGNCCNGTNATHYTNTTYYTNGAYGARATHGAYATGYTNTGYCCNMGNTCN GARGCNGCNAGYYTNGGNAAYAARCARYTNACNAGYGCNYTNGCNACNGARATGGAYAAR YTNCAYMGNTGYAAYGTNTCNAAYYTNATHGTNYTNGGNGCNACNAAYGCNATHTCNAGY YTNGAYCARAGYYTNMGNMGNCCNGGNMGNTTYGAYCARGARATHYTNATHAAYATHCCN TCNGARGAYCARMGNGTNTCNATHYTNGTNACNYTNACNGCNAAYYTNCCNYTNTCNTCN GAYGTNTCNTGYAARACNYTNGCNCARATGACNCCNGGNTTYGTNGGNGCNGAYYTNAAR ATHYTNTGYGARGARGCNGTNAAYCAYGTNCAYGARAARGARTCNACN------------ ---GARATHTGYATGGARGAYTTYAAYTTYGCNYTNCAYAARACNGTNCCNTCNYTNAAR AARGGNTCNGARTGYGTNGTNGAYYTNAARCCNGTNAARTGGGARGAYATHGGNAGYYTN GARGARATHAARATGGARYTNAARCARTCNYTNGARTGGCCNYTNAARTAYCCNGAYATH YTNMGNAARCAYGAYATHCCNCCNACNAARGGNATHYTNYTNTAYGGNCCNCCNGGNTGY TGYAARACNACNYTNGTNMGNGCNGCNGCNACNTCNTGYAAYGTNTCNTTYYTNTCNYTN AGYGGNGCNCARGTNTAYTCNGCNTAYGTNGGNGARTCNGARMGNYTNATHTCNCARGCN TTYCARAARGCNMGNGCNYTNGCNCCNTCNATHYTNTTYTTYGAYGARATHGARACNYTN GTNGGNAARMGNAGYGTNCARTCNGGNCAYAAYMGNGTNCARGARMGNATHYTNTCNACN ATGYTNAAYGARATGGAYGGNGTNGGNAAYAARYTNGAYTTYAARYTNGAYTCN------ ---------------------------------ACNACNCCNGGNGARCARAGYCARYTN CARACNCARACNACNGCNGAYGTNCCNGCNAAYAAYGARGCNGAYATHACNGTNGARAAR AARGGNAAYAAYGTNATHGTNGTNGGNGCNACNAAYMGNCCNGAYATGYTNGAYGCNGCN ATHYTNMGNCCNGGNMGNYTNGAYAARCAYATHTAYGTNCCNCCNCCNGAYCARCARGTN MGNAARGCNATHYTNGARATHTAYTCNTCNAARATGGCNTGYCARGARATHGAYGTNGAY CAYYTNGCNAARACNACNGARYTNTAYAGYGGNGCNGAYYTNAARAAYYTNTGYAARGAR GCNGGNYTNCARGCNGTNMGNGARGARATGACNAARGCNGGNGARGARYTNAAYATHTGY ATHAARGAYMGNCAYTTYACNAARGCNYTNGARAGYATHCARCCNTCNYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARGARCARATGGCNAARAGYMGNGARATGTCNCARCARATHGCNAAYATGGCNACN YTNACNTCNMGNTCNGTNAARGCNAARGCNGCNATHAARTTYYTNATHAAYAAYYTNTCN ACNGAYGAYGARGAYYTNYTNCCNTCNYTNAGYAGYCARCCNGAYGARTCNCARAAYTGY TCNAARTAYMGNCCNATGACNYTNCARGARYTNGTNCARGCNYTNACNGARATGGTNMGN TCNAARGAYGARGCNYTNGCNCARCAYAARYTNGCNTCNCARGTNYTNGCNMGNMGNYTN GARCARGTNGARMGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AGYYTNAAYMGNYTNTAYATHTCNYTNYTNGARGAYCCN TGYGCNACNATGTTYTAYYTNYTNYTNYTNGTNTTYGGNTTYATHCCNTTYTTYACNTTY ATHTTYTTYATHATHGGNTCNTTYTTYYTNGGNGTNGTNTGYTTYTGYGTNTCNCARACN YTNGTNTTYAGYATGTCNYTNTTYGTNTTYGGNGGNTTYATGGTNTTYATH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARATHGGNACNTCNCAYGAYAAYACNACNCAY TTYTTYATHYTNYTNATHMGNAAYAAYAGYCARGTNATHTGYACNCARATGYTNTCNACN CAYGAYTCNATGATGMGNGGNAGYYTNGAYTTYCCNAAYYTNATHAARATHAAYGGNATH ACNGGNGAYTTYAARYTNGCNGTNGAYATHTAYGGNATGAGYGTNCARMGNGARYTNTCN AARGAYAARAARMGNAARACNCCNAARAARGGNAARGGNTAYGCNACNGCNYTNGARAGY CCNGGNGGNCCNACNGCNGTNMGNACNACNAGYTTYAGYCAYGTNGAYMGNGTNGARYTN ACNATGMGNAGYYTNGAYAARAAYTCNTTYCAYYTNGAYMGNYTNCCNCAYYTNTCNCCN YTNCAYGGNCARATHTTYATGMGNTTYAARTGYYTNATGGARTCNCAYGTNGARGARMGN GGNTTYYTNACNATGTTYGARGAYGTNAGYGGNTTYGGNGCNTGGCAYMGNMGNTGGTGY GTNYTNTCNTGYAAYAARYTNTGYGTNTGGAARTAYCCNGAYGAYGARACNMGNAARGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYTTYGARTCNTCNAAR ATHGGNACNCARGARTAYTGGGAYGAYACNTAYGARAARGARYTNGAYAAYTTYACNGAR TTYGGNGAYGTNGGNGARATHTGGTTYGGNGARGAYGCNCARCARMGNATGGTNMGNTGG GTNTCNGARAARTGGGARGTNCCNACNTCNGCNAARATHYTNGAYYTNGGNTGYGGNAAY GGNATGYTNYTNYTNGCNYTNMGNGARGARAGYTAYGARAAYYTNACNGGNGTNGAYTAY TCNGARAAYTCNATHAARYTNGCNMGNAARATHGCNGAYAGYGARGGNGCNACNAAYATH TCNTTYGARGTNTGYAAYATHYTNTCNYTNGARGARACNGARAAR------CAYAARAAY TGYTAYGAYGTNTGYTTYGAYAARGGNACNTAYGAYGCNATHAGYYTNAARAAYACNGAR GAYCCNACNGAYMGNAARYTNTAYATHTCNCAYGTNCAYTCNATGYTNAARGAYAAYGGN ATGYTNATHATHACNTCNTGYAAYTGGACNAARTCNGARYTNGTNCARCAYTTYTGYGAR GAYTTYGAYATGACNGAYGARGTNCCNTCNCCNAARTTYACNTTYGGNGGNCARACNGGN CARACNGTNACNACNYTNATHTTYACNMGN---------YTNYTNGTNTTYCCNGARGAY GGNATHTAYGGNATGGTNTTYAARGGNMGNAARTCNATHGTNCCNTTYYTNGARGTNATH CCNAAYCCNAARYTNGCNACNTGGAAYCCNTGYAAYAAYAAYAARAARACNCCNAAYACN GARGTNCARCARGCNYTNAGYTGYATGGCNAARGARAAYCARATGTAYATHGTNGCNAAY ATGGGNGAYTTYGTNCCNTGYGTNMGNAARATGGAYCCNGCNTGYCCNGAYGAYGGNCAY TAYCARTAYAAYACNAAYGTNGCNTTYGAYTCNAGYGGNAARYTNGTNGCNAARTAYCAY AARACNCAYYTNTTYTAYGARGARCARTTYGAYTCNCCNAARCCNGARGTNGTNTAYTTY GAYACNCCNTTYGGNMGNTTYGGNYTNYTNATHTGYTTYGAYYTNYTNTTYAARGAYCCN GCNGTNACNATGGTNACNGAYCAYAARGTNACNAAYATHATHTTYCCNACNGCNTGGATG GAYGCNYTNCCNYTNYTNTCNGCNATHGGNTAYCAYTCNTCNTTYGCNMGNGGNYTNGGN ATHAAYYTNYTNAGYTCNAAYATHCAYYTNCCNGCNCAYMGNTTYCARGGNAGYGGNYTN TTYACNCCNAARGGNGCNGCNAAYTTYCAYTAYTCNAAYGCNAARAARTCNCCNGGNAAR YTNGTNGTNTCNACNYTNGAYGTNATH---------------CARTCNGGNATHATHAAR AARCAYGGNAGY------------GAYATHYTNTCNGCNCCNAARAAYATGCAY------ ------------------------------------------------------------ ------------------------------ACNAAYGTNAGYGARCAYTTYGGNGCNCCN YTNTTYAARGAYATHTAYACNTTYCARGCNYTNAGYCAYTCNTCNGGNAGYATHAAYGTN TGYCAYAAYAARGTNTGYTGYTCNYTNAAYTAYACNTTYGCNGAYAARACNCCN---AAR GARYTNTTYGCNTTYGGNGCNTAYGAYGGNYTNCAYACNTTYGARGGNCARTAYTAYTTY CARACNTGYGCNYTNGTNAARTGYGCNGAYAAYTCN---GAYMGNTCNACNTGYGGNTAY TAYACNTTYGAYTCNGCNACNAARTTYTCNTCNTTYTCNATHAARGGNTAYTTYCARACN MGNTTYATHTAYCCNCARGTNYTNGTNGCNGARAAYCARCARYTNATGYTNACNGAYGAR TCNACNTGGTCNTTYAGYAAYTCN---CAYYTNAAYGCNGARTCNGGNGTNAGYTCNCCN YTNATHTCNGCNATHYTNTTYGGNMGNGAYTAYTCNMGNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARGGNGCNCCNYTNTAYACNTCNACNTCN---GGNGAYTCNAAY TGYTAYYTNACNGGNATHGTNGTNTCNTCNYTNTGYTGGAARAGYAAYGARTGGGTNGGN YTNTCNGTNGTNTGYGGNATHCARAGYATHYTNCAYTCNATH------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GCN GAYYTNTCNYTNGAYGARTTYATHAARCARAARAAYGTNAARATHCARATHMGNAAYCCN TCNAARGGNCAY------------GTNCARMGNACN---------YTNAAYGTNAAYYTN AARTTYCCNGCNAARCCNATHGARMGNACNTTYGAYGCNMGNTCNAARYTNGGNCCNAAR ACNATHCCNGAYGCNMGNGAYAARATHATHATHAAYAARAARAGYGGNAARGGNGAYGCN MGNAAYAARATHGTNCARAARCARGTNGARAARGGNACNTTYGAYGCNMGNTCNATHYTN CARAARCARACNAARAAYACN------------------------AAYGGNGCNATHACN CCNMGNCCNYTNATG---------------------CCNATHACNMGNACNYTNTCNAAY ---------------------TCN---------TTYGTNGGNCCNCCNCCNGGNACNCAR GTNGCNTTYACNGGNAAYTCNYTNCARATHACNAARMGNGGNATGGGNATGCCNCCNATG CCNYTNAAYGTNAARGAYTCNGTNCCNATHATHCARATHMGNAAYGAYMGNTAYCARCAR ------------------------------AARCARCARATHCAYCAYCCNCCNTGGCCN CAR---CCNCCNCCNGCNCARCCNGCNCAYATHGGNAAYGAYCAYTAYMGNACNCCNCCN TCNTAYCCNTTYTCNTCNCCN---CCNCCNTCNYTNCAYTAYCARGAYYTNGAYGAYCCN AAYTAYCAY---AAYTCNTCNATHAAYGTNCAYAAYATHCCNAARATHAGYGTNTCNAAY TTYAARTCNGTNGARGCNGCNGGNATGMGNCCNGTNTCNGCNMGNCCNATGTCNGCNMGN CCN---------ATGTCNGTNMGNCCNGCNCCNGCNMGNCCNGTNTCNTCNCARCARGCN GCNACNYTNTCNGTNAARCARCCNGTNTCNATGATGCARTCNGGNYTNAARMGNMGN--- CARCCNCCNGTNCARGARACNATHGGNCCNYTNAARYTNGGNAARGGNGGNGGNCCNGGN GTNGAYGTN---------GGNGTNTCNCCNCCNAARMGNGCNAAR------GGNATHYTN ------CCNAGYGAYATHGARATHGCNGARYTNGARGAYAAYTCNAARTTYGTNAGYCCN ATHCARGGNTTYMGNATHATHGTNACNAAYYTNTTYACNGGNGTNACNCARGARGAYATH ATHGARYTNTTYGGNGTNGTNGGNCCNYTNAARAARGCNMGNYTNYTNAARGCNGGNTCN GCNGARGTNGTNTAYACNYTNMGNGARGAYGCNYTNAARGCNGTNCARAARTAYCAYGGN MGNGARYTNGAYGGNCARCCNATGTAYGTNAARATGACNACNCCNTCNGCNGCNGTNGTN AARTAYCCNATHGGNAAR---GAYCCNGAYATHACNGGNGARGCNYTNMGNYTNTAYAAR AARCCNAGYAGYYTNGGNCCNYTNCCNMGNGCNCCNGTNGARGTNCCNACNATHCARMGN GCNYTNTTYAARGTNGGNCCNCCNGCNCCNAAYAARTCNGTNAARTTYACNGTNAARATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNYTNCARGTNATHGARTGY--------- ---AARAARACNGARGARTGYAARACNTGYAARGARATHGTNGAYAAYTTYCAYAARGGN YTNGARGCNACNGCNAARTCNAAYTAYGGNGGNGGNAAYACNAAYTGGGARGARAARTCN YTNGGNTCNTAYGCNTTYAGYGARGTNMGNYTNGTNGARATHGTNGARAAYYTNTGY--- ---ACNTCNTCNGARTGYCAYACNATGYTNGARAARCAYGARGAYYTNGTNGARAGYTTY TGGTTYAARGARTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGGNGGNACN GARAGYAARMGNMGNGTNGTNGTNGARGAYATHAAYGGNGARGGNGTNGTNCARGTNACN GAYGCNGTNGTNMGNMGNATGAARGGNYTNGCNGARGCNCCNCCNGCNAARGCNACNCCN GCNCAYMGNCCNGAYGARGARMGNTAY--------------------------------- ---------AARGARATGACNAARGARATHGARGARTTYTAYTCNGARAARYTNGARGAY YTNGARAARAARAGYAARAAYYTNCARAAYACNTCNAAYGARCAYTTYTCNAAYGCNGTN AARGARGTNGARCARAARTTYYTNAARTAYGCNACNTCNCCNGTNTGYCARGAYYTNCAR ACNAARGTNYTNGARTGYTAYCARAARAAYCCNGAYTCNATHYTNGAYTGYTCNACNGTN GTNAAYGCNTTYACNGTNTGYGTNGAYMGNGCNMGNATGACNGTNTCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARGGNAAYYTNMGNAARGAYGAYAARGAYGTNCCNGARTAYYTNTTYTCN MGNGCNTGYGCNGGNACNACNGCNYTNGARYTNATGGCNGGNATHGARAARYTNACNAAY GGNACNATHGGNGGNMGNTTYTTYCAYTTYTGGCCNMGNMGNAARGTNAARYTNYTNCAR TGGYTNGCNTAYTGGATGAARMGNGGNGCNATHCCNATGGCNACNYTNAAYYTNCARYTN GGNCCNCAYTCNATGTGGGARGTNCCNGAYTCNTGGCAYCAYCARATGGTNTAYGGNGTN GGNCAYCARGGNYTNTAYYTNACNAAYCCNYTNGARATHGTNTCNGARMGNACNGCNATH AARCARYTNGARAGYGAYTCNATHYTNATGGTNMGNMGNCARGAYATHATHGCNMGNTTY AARGARTGGACNGAYYTNGGNCARYTNYTNGARCAYCCNGAYCCNMGNTGGACNTCNATG AAYGTNYTNGGNCARGTNGTNAAYGTNYTNMGNGARTGYAAYATGCCNTCNGTNCCNGGN TAYMGNCCNCARGTNACNTCNCAYATHAARATHCCNGCNTCNTAYGARGCNGGNATHACN YTNTTYATGCAYAARGAYCARCCNGCNTGGAAYGCNYTNYTNGCNGCNCCNCARYTNCCN YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNGARGARGGNTAYAARAGYATGGAYAAYTTYYTNGCNGARGGNATGGTNAAR AARYTNCARGARGGNATHMGNTCNGARAARGAYMGNAARTAYACNGTNCAYATHTCNCCN YTNGARATHGCNGAYYTNGCNCAYCCNACNATHCARCARYTNATHCAYYTNCAYCCNTCN YTNACNATGGTNTTYCARCAYCARGCNGTNAARYTNAARAARAARAARGGNTAYGCNGAY GCNGTNTTYMGNACNGTNACNGAYYTNAARGARTTYGTNTAYCARYTNACNCARGTNAAR GTNTTYGARMGNCARYTNGAYGTNACNATHACNGCNGAYGTNCCN---------GAYTTY ACNATGTCNTTYTCNATHCARYTNCAYMGNAAYYTNAARYTNMGNAAYYTNATHAAYAAY GGNGAYGAYCCNGTNATHAAYAARCCNATHCCNATHGAYGARAGYMGNCAYAARATHCAR TTYGARAARGTNCCNGCNATHGCNAAYGCNGCNYTNATGCAYAGYYTNTTYCCNTTYGCN AAYAAYGTNCAYATHMGNGARTGYGTNGGNGAYAARACNGAYAARTCNAARTTYCAYGGN CCNYTNACNGTNTGYTAYGTNAAYGARCARTGGYTNGAYGCNGTNATGGCNTGYTGYACN GAYTTYGCNGTNAAYGGNTTYCCNYTN--------------------------------- ---------------------------ACNGARATHGARTGYAAR--------------- ---------------------GAYAARGAYGARGARGAYGARGTNACNAAYGAYGARGAY GAYTCNYTNTCNMGNYTNACNCARGAYGTNTAYGAYGARGTNATHAGYTCNATHAAYAAR YTNAARGARATHACNCCNAAYAAYCCNAARYTNAARGARATHYTNAARATGCARGARMGN YTNGAYGCNTTYCARAGYTCNYTNAAR------------------------TCNTCNGAY CAYTCNGAYATHTCNATGGAYCARAGYATGACNGCNTCNAAYGGNGARAAR--------- ------------------------------------ACNGAYATGGARAARYTNGARGAY ATHYTNGARGARAARGARAARATHGARCAYGCNAARGARYTNACNMGNAARAAYCARMGN GARAARGARATGAAYGCNAARAARGARYTNGARAARAARMGNAARACNCARTGGGCNAAR AGYYTNATHTCNGAYTTYAAR---------CARACNGCNCCNGTNGARAARAARGGNGTN AGYAGYGCNGCNGARCARATHYTNAARCARMGNGARATHMGNYTNAAR------------ ---GARAARGARGARGARGARAARMGNAARGARGARGARAARAARGARAARGARAARCAR MGNATHGARAARGARAARMGNCARGARGARGARAARACNTTYYTNATHAARMGNATHGAR GARGCNMGNCARMGNGAYATHGARAARGCNGARGARYTNTCNTCNYTNCARTCNATHTGG AARTCNGARACNGAYCAYMGNTCNTCNTCNMGNGAYMGNMGNAGYCARAGYAARMGNTCN ACNGARAARAGYTCNCAYAAYGAYGGNGAYGAYGTNGAYCARAAYTCNCCNAARMGNGAR AAYATHCARAAYGCNTAYGTNATHGARGARCAYGARTAYGARGTNYTNAARGCNMGNAAY CARYTNCAYACNYTNCCNGCNAAYTAYAARGTNACNGTNGCNGTNGCNGCNAAYMGNTGY TGYCCNGCNACNGCNTGYCCNGCNACNMGNTGYTTYMGNGARTTYTCNTCNYTNATGGAR CAYTGGTCNATHTTYCAYGARCCNAARAGYACNATGMGNTTYTGYGCNAAYTGYACNGCN TAYTTYATGACNGTNGARGARYTNGARAGYCAYATGATGAARATHCAYMGNYTNTCNTCN AARGARGCNATHTAYAAR---TGYCARAAYGCNMGNGTNAARATHATHTCNAAYCCNAGY TTYMGNGAYCCNTCNCCNTTY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TCNMGNTCNMGNTCNAARTCNMGNTCNMGNTCNATHAARMGNAGY--- ---CCNMGNMGNTCNMGNAGYMGNMGNTCNTAYTCNTCN------TCNMGNTCNMGNAGY MGNTCNMGNTCNMGNTCNAARMGNTCNMGNTCNAARAGYGTNGARAARGTNCCNGTNAAR MGNTAYMGNMGNGARAGYYTNTCNTCNAGYTCNGCNYTNAGYGGNATHGAYTCNGAYTCN GARGAYAARGGNTCNAARMGNACNGAYTCNAARTCNAARYTNMGNATGAAYGTNGGNGGN AAR---------------AARYTNAGYAGYAARAGYAAYTCNCARGCNGTNAARGARACN CCNAARGARAARYTNAARMGNMGNATGCARGCNCARYTNAAYAARCARTTYAARGCNGAY AARAARGCNGARATHAGYAARYTNTCNAARCARGARCARGARMGNYTNGAYMGNGARGAR GARATHMGNGARATGGCNYTNGARATGMGNMGNMGNGARMGNGARAARMGNCAYMGNGAR MGNGARGARGARGARAGYGARMGNGARACNGGNCAYMGNMGNMGN---------AGYTCN TCNAGYTCNAGYAGYTCNGGNAARAGYAARAGYAGYTCNAGYAGYMGNAGYMGNAGYCCN GTNAAYMGNAARMGNGAYGAYGGNGAYGARGARGAY------------------------ ---------------------------------GAYTCNTCNYTNTGYGCNGTNYTNAAR YTNGARGARCAYGARAARGCNMGNACNCARACNACNGARTGYYTNGTNTCNGTNAGYGGN YTNGARGCNMGNATHGARGAYMGNYTNAAYGTNTAYAARTCNAARAGYGTNACNGAR--- ------AGYATGGAYTAYAGYACNTGGMGNGARGCNGGNATGTCNGTNCAYCARATHAAR ACNTGYYTNAAYGARGTNTCNAARYTNATHTCNYTNGCNTGGATHACNGARYTNCCNCCN GTNACNGARAARGGNCARTTYTAYGAYCCN------------GARACNGARGGNYTNAAR TCNGARYTNGCNGCNATHAARGCNAARTAYGGNYTNYTNCARCARACNACNAARGAYCAR CARGGNAARATHCAYGTNTCNAARCARMGNCARAARAGYTGGGARCAYTCNGTNTGYMGN CAR---------AARGGNAARMGNTCNMGNAGYYTNTCNGARTCNTTYGAYGAYTAYAAY GTNATGGARGARMGN---------------GARATHATH------------GAR------ ------MGNGAYCCNGAYGGNGARMGNTTYTCNYTNATHAAYGAYAGYAARATHYTNAAY CCNGAYYTNAARAGYCARTAYGAYMGNATHAARMGNGCNTAYGCNGAYYTNYTNTAYAAR TGGGGNYTNYTNAAYCARMGNACNCARATHYTNAARCAYACNGTNCCNGTNCARAARAAY CARAAR---ATHGARTTYTCNATHCCNTGYTCNAAYTGYMGNGARAAYGCNATHACNGTN AARTGYCAYCARTGYCAYTAYCCNTCNYTNAAYTGYTCNATHTGYCAYATHGGNGTNMGN GGNCARGCNAAYATGTGYTTYGARTGYGGNCAYGGNGGNCAYTCNTAYCAYATGMGNGAR TGGTTYMGNACNAAYGTNYTNTGYCCNTCNGGNTGYGGNTGYTGYTGYYTNCAR---AAR ACNGCNYTNTCNAGYACNAGYACNACNAGYMGNCARGARGCNAAYAAYATHCARAAYMGN AAYAAYGGNGTNGARTCNGAYAGYTCNTTYGCNTCNCARCCNGCNGCNCARTCNAARTAY GAYATHAARYTNYTNAARCARAAYCARMGNYTNYTNAAYGARGTNGARMGNYTNGTNGGN CARATHCAYATHGCNAAYCARAARAAYACNGARYTNGTNAARGAYGCNGAYAARGGNAAR MGNGCNACNGARYTNGARGARAARTCNGTNAAYYTNGTNGCNGARAAYGAYGCNCARGAR AARAARYTNMGNGARGCNGARMGNCAYYTNGAYGARGGNCARMGNMGNYTNGGNGARYTN CARAARMGNATHCAYTTYACNGARACNGARGTNGTNGAYYTNMGNGCNGARYTNGCNGAR ATHMGNYTNGTNAARMGNGARYTNGARACNCARMGNGAYGAYGCNYTNCAYAAYTTYAAY ACNGCNCARGAYTCNYTNGARGAYTAYCARAARAARACNCARGARAARATHATGAARYTN GARGARAARGARGAYCARYTNCARGARGCNYTNAAYMGNACNAGYCARGARMGNGAYGAY YTNYTNGAYCARYTNTCNGGNATGGARATGACNATHGCNTCNCARGARGCNCARATHGAY MGNYTNYTNAAYGAYGTNACNGARGARGAYAARMGNAAYCARGAYYTNGARAARAAYAAY CAYCARYTNMGNGCNCARYTNGAYYTNYTNACNGCNCARATHAGYGARYTNGARCARCAY AARAARGARGCNAARGAYYTNAARAARGARAARGARAGYATGAARYTNGARYTNAARAGY CAYAARTCNATHGCNAARGARTTYAARTCNYTNYTNACNYTNYTNCARAARTCNGCNGGN AAYATHCCNGGNAAYAARGCNGAYGAYAGYGGNATHAGYTTYAARACNGCNCCNTTYGAY TTYGGNGGNTTYGGNGAYTCNGCNGARGGNGGNATGYTNGCNGTNGARYTNAAYTGYAAY AAYAAYGGNYTNGARAGYTGYTGYGARCCNTGYGARGGNGCNAAYATGATGTGYGARATG MGNAAYYTNGTNACNAAYATGGAYGGNGARATHCARMGNYTNMGNTGYGAYYTNAARCAR MGNGAYGCNGAYGAYMGNACNTAYGCNAAYYTNMGNGARGARYTNAARGTNYTNATGGAY AARGTNGARAGYGGNATGTGYCAYAAYMGNGAYYTNGARTGYCARGTNTCNCARYTNGAR TGYGAYAARAARAAYYTNMGNGGNAARYTNGARGARACNYTNGGNTGYYTNGARGARMGN GAYMGNGCNYTNCARTGYYTNGARACNMGNYTNAAYGARMGNAGYTGYCARATHGTNTGY YTNCARGARGAYATHGAYCARMGNAAYTGYMGNATHAGYGCNYTNGARAAYCARGTNCAY GARYTNCAYAARMGNYTNMGNGARGAYCCNGAYAARGAYGARTCNCCNGCNYTNAARGAR GCNMGNCAYMGNATHGARGARYTNGARGCNATHYTNGTNTGYAARAAYAARTCNYTNGAY GARATGGGNGGNAARYTNTCNGARACNYTNMGNGARTTYMGNYTNYTNAARAGYGAYTGY ACNAGYGARAARGARTGYYTNGARAAYAAYATHACNCARMGNGAYACNGARATHCARAGY YTNAARGAYGAYGTNGARGGNAGYMGNCARAARYTNYTNTCNYTNAGYAARCAYATHGAR GARCARAARYTNGCNATHMGNAAYAARGARGAYMGNATHAGYTGYYTNCARMGNGARYTN GARGARGTNAARTTYGCNGCNGARAARACNGARAARYTNYTNCARACNCARYTNGAYGAY CAYTCNAARMGNYTNAARGCNTGYCARGAYCAYTGYGCNGARYTNGARCARACNYTNTGY TCNTGYMGNAGYGARGTNTGYGGNCAYYTNCARTCNATGGAYGARATHMGNGCNMGNTAY GARGCNGARYTNGARCARMGNGAYTCNTGYATHMGNAARYTNAARGARGAYATHMGNATH GCNGTNGARGARYTNAARTGYAARATGGARGAYAAYCARTCNYTNGARMGNTCNYTNTGY GARGCNMGNAAYAARGTNCAYCARATHTGYGGNCARYTNAARGAYGCNGAYACNAAYATH CARTGYYTNAAYATHAARATHACNGARATGGARAARCARATGYTNAARGARAARTCNAAY TGGATGAARGARTCNGARGARATGGARMGNMGNATGCARCARTGYTGYAAYAAYYTNTCN GTNGCNAAYACNGAYATHGAYACNYTNAARCARCAYYTNGCNGARAARAARAGYCARGTN GAYTGYATGCARGCNGARAARATHCAYATGTGYCARGARATHAARAARYTNAGYGAYCAR GTNTGYTGYYTNCARGARCARATHMGNAARATGGARACNGAYAAYCARGARYTNTGYMGN CARYTNCARCARAARATGGARTGYATHMGNGAYYTNGARAAYGTNATHMGNACNAARGAY CAYGARYTNMGNTGYYTNAGYAARTTYGTNCARGARATGGARAAYAAYGTNGAYGCNGGN GTNGTNCCNCARYTNGAR------GCNCARATHAARGARYTNACNGARAARYTNACNAAR TGYCARGARGARTGYAARTGYAARTCNACNATGYTNTGYGARTGYGARGARGGNTTYAAR CARTGYCARATGYTNTGYAARGAYAARGAYAGYGARATHTCNYTNYTNMGNTGYCARATH GARGGNYTNAAYGARAARYTNAAYGAYMGNATHGCNMGNGTNGAYGARYTNGARMGNGGN ATHGARAAYYTNCARAARGAYGTNGARMGNMGNATGATGMGNGTNGAYGARCARYTNAAR AARTAYGARACNGARYTNGCNGAYMGNATHCARGARATHGCNACNYTNAARGARTGYGTN ACNACNTGYCARYTNAAYYTNTCNGARAARCARGAYGARYTNCAYCARCARGARCARAAR AAYAAYYTNYTNGCNGCNGARATGGARTCNATHAAYYTNAARYTNAARGAYGCNGARGAY TCNMGNGAYCAYYTNGGNAAYCARYTNGCNGARAARAARGGNGARGTNACNGARYTNACN CARCARYTNMGNYTNAAYMGNGARCARATGCARAARCARCAYGARGAYYTNGTNCARTGY MGNCARGCNYTNTCNTGYGCNCARMGNGAYTCNGAYMGNYTNMGNMGNGARYTNGAYGAY GCNYTNGCNAGYYTNGARCAYMGNGARTGYGARATHTCNMGNYTNAAYGARGARMGNMGN TGYYTNATGGARAARGTNGCNCARATHTCNTGYCARATGGARCARGAYACNTCNATGYTN MGNAAYCARYTNGCNGARACNAARTGYMGNYTNGARAARGARYTNGARTGYYTNMGNAAY TAYTCNTGYCARYTNGARGGNAAYAAYGCNGCNYTNAGYAAYAARYTNTCNYTNACNCAR MGNCARATGATGCARATGGARAARTGYTTYCAYCARAARYTNGAYACNATHAAYMGNAAY YTNGAYGAYYTNAAYACNAARYTNAARATHMGNGARGAYGARYTNATGGCNTCNAARGAY TGYYTNGAYYTNAARGARTCNGARATHGCNMGNYTNAARAARMGNYTNTGYAAYGCNGAR AARGTNGCNTGYAAYGCNAAY------TGYCAYAAYAAYTGYGGNCARGAYGARGARMGN YTN---GTNGAYTAYAAYGAYTTYCARCARGAYGAYGTNATHAGYTCNGARAGYTGYATH AAYYTNGCNGCNGAYGTNGGNAAYGAYMGNMGNAAY---------------YTNTCNAAR GARGARATHGCNAGYGAYGAYGARGGNCAYAGYAGYGCNMGNAAYAGYYTNGGNGTNACN GCNGTNCARGARMGNYTNMGNAAYAAYCARATGMGNCARAARGARATHGARMGNCARYTN AARTCNYTNGARGARGGNAGYCARGAYGAYGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNAAYACN GCNYTNGCNATHGTNCCNTAYCARGARAAYAAYYTNATGCCNCAYGARAARAARAAYMGN ACNTTYCAYATHGCNGGNCAYAGYTTYAARATHCARCARGAYTGGCAYAGYGGNGGNGTN GCNGCNGTNGTNTGGGAYGCNGCNYTNGTNYTNGGNGARTAYYTNGCNACNAAYMGNCAY YTNGTNCAYGGNAARTAYGTNYTNGARYTNGGNGCNGGNACNGGNYTNGCNGGNATGGTN TCNGCNYTNYTNGGNGCNACNGTNATHGCNACNGARMGNGARGARGCNATHCCNCAYYTN YTNTCNACNATHTCNGARAAYMGNATHGGNAARAAYTGGAAYATHCARGCNAARACNYTN GAYTGG------------------ACNCAYGAYATHGAYCCNGAYTTYCAYYTNGTNATH GGNGCNGAYATHGTNTAYATHGARAGYACNTTYCCNCAYYTNYTNAARACNYTNAARTCN GTNGTNACNTCNCCNAARACNAARATGYTNYTNTCNTGYMGNATHMGNTAYGAYMGNGAY YTNAARTTYYTNGARATGYTNAARGARGTNTTYCAYGTNATHGARATHTTYTAYGAYAAR GARMGNGAYATHAARATHTTYTCNGCN---------GARYTNATHACNCAYAAYGGNGGN TGYCAYTGYGGNGCNGTNMGNTAYTCNGTNGARGCNCCNTCNCAYYTNGAYGTNATHAAR TGYAAYTGYAGYATHTGYACNAARAARCARAAYCAYCAYTTYATHGTNCCNAARTCNMGN TTYAAYYTNYTNCARGGNGARAAYTGYYTNACNACNTAYACNTTYAAYACNCAYAARGGN AARCAYACNTTYTGYAARGTNTGYGGNGTNCARTCNTTYTAYTCNCCNMGNTCNAAYCCN GAYGGNTAYGGNATHATGCCNCAYTGYYTNGAYCARGGNACNGTNAARTCNATHAARTAY ACNACNTTYGAYGGNACNCARTGGGARGARACNATGAARACNTCNAAYATHGCNGARMGN TCNAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TCNTAY CARCARCAYACNAAYGARGARGTNAAYATGGARGAYYTNTCNGTNMGNCCNGAYAAYGAR GCNAGYGCNTCNACNTCN---------------CARYTNACNGAYTCNATGTCNGCNMGN CARMGNTCNYTNYTNAAYATHGTNACNAARGARCARAARAARTGGAARGGNACNGTNCAR GARCARMGNMGNAAYATHTAYGAYMGNCAYTCNATGYTNAAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNGGNYTNAAYGCNAGYMGNAARGCNYTN TCNACNGCNYTNYTNCCNTTYAAYTCNYTNMGNGTNCCNGTNTAYCAYATHATGGGNAAY CAYGARTTYTAYAAYTTYTCNMGNTCNTTYTGYYTNAARTCNCCNYTNAAYAGYTTYYTN TCNACNGARATHACNTGYCARACNGAYTGY------------------GTNTAYMGNACN TTYYTNTCNCAYCCNAARYTNMGNGTNGTNYTNYTNGAYACNTAYGARGTNAGYGTNYTN GGNTAYACNGAYGAYYTNGARAAYGARAAYTAYGTNAARGCNYTNTCNYTNYTNCARTCN AAYAAYCCNAAYACNGARAARAAYGAYACNACNGGNYTNGARGGNGTNGARMGNMGNTGG GCNGCNTTYAAYGGNGGNATHAGYGARAARCARYTNGARTGGTTYGCNCARGTNYTNGAR AARGCNCARAARAARGARGARAAYGTNATHGTNGCNACNCAYGTNGGNATHTAYCCNTCN YTNCCNGARAAYTAYTCNATHTGYYTNGCNTGGAAYTTYCARGARATHYTNGAYGTNATH TAYAARTAYAAYTGYGTNGTNGCNGTNYTNGCNGGNCAYCARCAYGCNGGNTTYCARCAY YTNGAYGAYCAYAARGTNCARCAYATHTCNTTYCARGGNGTNGTNGARACNCCNCCNGGN GAYAAYGCNTAYGCNACNGCNMGNYTNTGGAAYAAYTCNYTNACNATHACNGGNGTNGGN AARGTN------------------------------------------ATHYTNAAYGAY TGGACNAARMGNYTNGARGCNGARAAYGTNCCNAAYGCNACNYTNAGYGTNGARTCNATH GCNGCNMGNGCNATHGGNATGAARACNYTNCARGAYGTNGAY---YTNACNCARTGYGTN AGYGARGARGCNGTNGCNTCNATHAAYAAYATGTGYGARATGMGNMGNGARMGNACNCCN YTNCCNTAYATHGTNGGNGARTGYGARTTYGAYGGNYTNACNYTNAARATGAARMGNCCN GTNYTNATHCCNMGNCCNGAYACNGARGAYYTNGTNGAYYTNTGYMGNCAYACNATGAAY AARGAY------AARTCNYTNYTNGAYGARTAYCCNGTNTTYYTNGARYTNGGNGGNGGN ACNGGNGCNATHACNYTNGCNYTNYTNAAYTCNTAYAARCARATGTCNGCNGTNTGYGTN GAYTAYTCNYTNGARGCNTGYGARYTNACNAGYGARAAYGCNGAYAAYYTNGGNYTNGCN GAYMGNYTNGTNGTNYTNCARMGNGAYTTYACNCARGCNGARGCNATHAARGARTTYMGN AAYATGTCNCCNTAYAGYTTYYTNATHGCNAAYCCNCCNTAYYTNACNTCNGAYGARATG AAYCAYTTYCCNACNGARGTNATHAARTTYGARGAYCAYYTNGCNYTNCARGGNGGNGCN GAYGGNYTNGARYTNATHACNTCNATHYTNAAYAAYGCNGCNGAYTGGGTNACNCCNGGN GGNCAYGTNTTYYTNAARGTNGGNAARAAYCARCCNYTNCARGTNCARGAYTAYGTNATH AARAAYAARGAYYTNGTNMGNATGGAYTAYYTNCARACNGTNAGYGAYMGNTTYAGYMGN GARMGNTTYTGYCAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNCCNYTNTTYAARGARGAR GTNGAYGTNCARGGNGCNGAYGGNCAYATHTAYAARGGNMGNATGGAYTCNAAYMGNYTN GARGCNAARYTNCCNGTNAAYYTNATGGCNAARCARACNCCNCAYCCNGCNTAYATGGAR CCNAARGCNCCNTCNCCNCCNCCNYTNAAYMGNCCNGTNTCNGCNMGNYTNCCNMGNCCN GGNTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GTNTAYTTYYTNGGNYTNGTNCCNGAYATH AAYTTYACNAAYTCNAARAARMGNGAYACNGARGCNCARYTNATHGAYATHGTNGARGAR TAYCARATHGAYGGNAARYTNCARGTNAARGCNACNGAYGARAAYAARGTNGTNATGAAY ATHTCNMGNCAYGGNATHAARGTNYTNGAYATHGCNGGNAARGARGTNYTNCARMGNCAY CCNYTNCAYACNATHGCNCARYTNACNGARTAYAAYGAYGGNTTYGGNCARCARAAYATH GCNGTNAARATHGGNCARGTNGGNAARACNGTNTAYCAYTGYTAYGTNTTYCARTGYCAY TCNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYAARGCNACNYTNGCNMGNMGNGARAARCARATHCARTAYGGNAARGCNACN CAYTCNTAYAARATGTAYAAYGARACNGTNGCNMGNAAYGARMGNYTNCCNGAYMGNAAR GTNCAYCCNMGNACNCCNGTNAARTCNCARAARTCNAGYMGNMGNAAYTGGGAYGCNCAR ATHAARGCNTGGAARAARTAYGTNCAYCARTGGGCNAAYGCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARCCNCARGAYACNATGGARCCNCCN CCNYTNCCNCCNCCNAARGCNCCNACNCCNCARCCNCCNCCNCCNCCNAARAAR---GAR GARAARAARGARGARATHAARCCNATGGTNCCNGAYATHCCNCCNGARCARGCNGARCAR TAYMGNAARYTNMGNGARAARGCNCARAARCAYGCNAARAARCARYTNMGNAARCARGAR CAYCARGCNAARGGNGARCCNGARAGYAGY------GAYGAYGAYGARGARATHACNAAR AARAARGARGAYGARGCNAARYTNGCNGCNGARATGAARGARATGGARGARGCNTCNATH YTNGCNGCNCARGGNGTNGARAAR------GTNGARGARAGYGGNGCNATHYTNGTNCCN ACNTCNCCNTCNCCNYTN---GTNCARCARCARGCNGTNTAYATHCARCARCAR------ ------CCNGTNGCNGCNGCN---------TAYGGNATGGTNTCNACNCCNCAYYTNGTN CAYGCNACNCAYCCNGCNYTNCARGCNGCNTCNTCNCARGCNGCNGCNTCNCAYCAYGCN GCNCAYACNTCNYTNCARCCNCARYTNGTNCARYTNCCNAAYGGNCARGTNGCNTAYGCN ACNCCNGCNAARCAYCARGCNGTNCCNATGCARGCNGGNGCNCCNGTNATHGCNATG--- CCNCCNCAYGCNGTNCCNACNGCNGGN---------GGNCAYCARTTYGTNTTYTCNCAR GGNGGNATHCCNYTNCARATG---GCNCAYGCNGCNGTNCCNGGNGCNCARTAYATGTCN CAYYTNATGGCNGCNCARGCNCARGCNCARGCNCARGCNCARGCNCAYGCNCARGCNCAY GCNCARGCNGCNCAYATHCARGCNGCNCARATGGCNCARGCNCARGCNCARGCNGCNCAR GCNCARGCNGCNCARYTNCAYGGN---------------YTNCAYGCNGTNCCNGCNGGN GTNCAYCCNATHACNCARCARGTNYTNCCNGCNGCNGCNYTNGCNGGNCARCARGGNCAR ATHATHYTNGTNCCNMGN---TAYMGNCCNCARATG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARATHAARMGNAARTTYGGNGTNCCNGCNAGYGARATGYTN ATHACNCCNGTNGTNGARTAYCAYGCNGAYAAYTCNTAYCARTTYAARCARCAYGTNTCN GTNAARYTNCCNCAYGCNYTNCCNGAYGAYATHCARCCNACNGAYATHCARTAYTAYACN TTYACNGTNGAYGAYTGYGGNAAYGTNTCNYTNGARYTNYTNCCNYTNAARACNAARGAY AAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGGAR GCNAGYAARATHTCNMGNYTNMGNCAYGARCARGARAARGCNTTYTCNGARACNGARGAR CARATHAARAARTTYGCNCARTTYAARTCNGAYTAYAARATHYTNCARTCNMGNYTNAAY ACNYTNCCNGAYAARYTNTCNCAYGAYGTNATGGTNCCNTTYGGNAARATGGCNTTYATG CCNGGNAARATHGTNAARACNAAYGARATHYTNGTNYTNYTNGGNGAYAAYTGGTTYGCN GARCARTCNGCNAARCARGCNAGYCARATHGCNGAYMGNMGNATHACNGARYTNGAYAAR MGNATHAARTCNYTNAARCARCARCARAARYTNYTNGARTCNMGNTTYGGNTTYACNTCN GARYTNAARGAYATGGCNGARGGNAARGGNGAYTAYAARGARATHGTNGARGARTAYGAY GARGARAARGARAARYTNTGGGAYGARAARCAYMGNGARAGYGTNMGNMGNGARAARGAY TGYCCNAARYTNGTNAAYGCNAARGGNGAYTGYGGNATHCARTCNCCNGCNYTNCCNATG CCNTCNACNACNGAYGAYGAYATHTGGTCNMGNYTNGAYGCNYTNGARGARCARGARGAY GARMGNGGNGARYTNAAYAGYTCNTTYGAYTCNTCNGAYGAYGARMGNGGNTCNAAYMGN GARGAYAARACNGTNATGAGYACNCARCAYMGNAAYGTNGTNTGGCARGAYGAR------ ------------------------------MGNGARATHGGNAARGAYTCNTCNTCNTCN TCNTCNTCNAAYGAYAGYGAYGAYGGNGARGARGARGARGARGAYGARGAYGGNGAYGAR GARGGNGARGARGARCAYGARAARMGNAARACNATHACNTTYTCNCAYAGYAARGTNCCN GCNACNAAYAAYAARCCNGTNCCNGAYTCNTCNGCNATHACNAGYCCNGGNGARATHTAY AARYTNTTYTGYCCNAARTCNATHYTNMGNAARAGY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGGTNTTYTCNGGNTCNAGYTAYAAYGARMGNGTNGGNAAYGARGAY GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TTYATHATHACN GCNATHTTYGTNGCNAGYTTYYTNCCNCAYYTNATHYTNAARGCNYTNCARGCNGTNAAR AARGAYTTYCCNTCNAAYGAYTCNCAYAGYCARGTNATHYTNTAYAAYGTNTTYGTNMGN TCNTAYTTYTTYAAYAGYATHGCNAAYTGYTTYATHTAYGGNTTYTGYAGYCCNAARTTY MGNMGNGARACNAAR--------------------------------------------- ------------TTYGCNGAYAARYTNAARTCNTCNGGNYTNACNGTNTGGTTYAGYCAR CCNGGNGGNGAYGGNAARAARACNAGYGARGCNATHYTNGGNTGYAARGTNTAYYTNCCN GTNYTNACNGARCARTCNGCNATHGAYAARAGYATHCAYGARCARYTNTCNYTNGCNTAY ATHTCNAAYTCNGCNATHTAYCCNYTNGGNMGNATHMGNTTYAAYYTNYTNGCNTCNAAR YTNAAYGGNGGNGCNMGNYTNATGYTNGCNAARATHAAYTGGTCNTTYATHTTYAARGAY GARGAYTTYGARGARAARACNGARACNATHATHMGNTGYATHAARAARGAYATHGARAAY ATHGARAARATHTTYGARGCNCCNCARGAYGAYTCNGGNTAYGTNGCNACNCAYGGNATG MGNATHCCNYTNACNYTNTCNCAYATHCCNCCNACNGGNGAYGARGARCCNGARTTYGTN ACNTTYAGYAARGGNATHGAYYTNAAYTCNATHAGYCARGAYACNCCNTTYTGGGAYMGN CAYTTYMGNGGNAARAGYGARATHTCNTGGATHGARTTYMGNGAYAARTTYYTNAARGAY TAYGGNGARAARATHATHGARGGNTTYTCNGARGGNATHGARGAYMGNAARAAYYTNTTY ATHAAYYTNATGTAYAARGAYGTNYTNMGNGGNAARAARATHGTNGARTAYTCNACNTAY GARAARTTYTGYGGNAARCCNCAYCCNCAYGCNTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHGAR GARGTNGARAARATGGTNAARGARTAYGARGARAARATHGARGAYATGGARMGNAARCAR MGNYTNACNGAYYTNAARGAYGARGARMGNGARGARATGAARAARGARAARGARACNATG AGYAARCARGTNCARMGNTAYAARAAYGARYTNATHGGNYTNMGNTGGCARAAYTGGAAR AGYACNGTNGTNTCNTTYGTNATHTTYGCNATHTGYTAYTTYATHTAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARMGNMGNMGNTAYGAYTCNGGNAGYTCNTGGYTNACNTCNGAR GAYGGNGAYGARTAYGAYACNYTNCAYAAYGARTAYGAR------------TCNGAYGAY GAYAAYTCNGAYYTNGAYGCNGAYYTNGCNCAYYTNAARCCNGGNAAYTGYGARTCNYTN ATHGARCAYGGNAARAARCARAARCARTAYTTYTGGCARTAYAAYGTNCARGCNAARGGN CCNAARGGNACNMGNYTNAARYTNTGYGTNGARTCNCCNACNGAYCCNCAYGTNYTNGGN GGNTTYGARGAYCCNGTNTTYGAYGARGGNAAYACNATHGTNGCNGGNATHMGNCAYGGN GGNAARGCNMGNAARGGNGAYGGNAAYGARGTNACNCCNAAYCCNYTNAARYTNTTYAAR ATHGGNCAYCARYTNYTNMGNYTNAGYAARAARATHAAYGCNTGYCARYTNGGNTCNGAY GTNCCNATHGARCARMGNAAYGARGCNMGNMGNGARAARAAYAARYTNGCNTCNMGNGCN TGYMGNYTNAARAARAARGCNCARCAYGARGCNAAYAARATHAARYTNMGNGGNYTNGAR ATGGARCAYGGNCARATHAAYACNATHYTNMGNCAYATHTGGCCNGARYTNMGNGARAAR GCNAAR---------------YTNYTNCARCARAGYGTNAAYCCNAARCCNGAYACNGAY AAYAAYYTNACNAAYAARATHACNAGYYTNATHTCNTCNAAYYTNAARAGYMGNGTNGCN TGYAAYACNACNGAYTTYGTNAAYAAYGTNATHATGAAYGTNGARAAYAAYGAYYTNAGY GGNGGNYTNGAYATHATHAARGCNMGNAARACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARGGNCARCAYTTYMGNGAYYTNATHACNAAYGARACNGAYMGNYTNACNAARYTN TCNAAYACNTGGAAYGAYYTNGCNACNGARGCNGCNGARYTNACNGARGARGTNYTNGGN CARATHMGNTCNACNGTNGGNAARGCNYTNYTNYTNATHGARCARMGNTTYAARCARTTY TCNGGNYTNGTNGAYAAYTAYGTNTTYGAYYTNGGNGARAARAARACNACNCCNACNGAY YTNCARGGNTTYTGGGARATGATHTAYTAYCARGTNGARGAYGTNGAYGCNCARTTYAAR ACNYTNGARCARYTNAARGARTCNAAYTGGCARGTNAARTCNAAYTCNCCN--------- ---------GTNAARAARAARATHGCNAARGARAARCCNMGNCCNAARGGNGTN------ ------AARTCNAAYTTYGCNGCNTTYAARGCNCARYTNCARAARAARAARGCNCARACN GCNTCN---------ATGGARGAYYTNAARAARYTNAARGTNCCNGARYTNMGNGARTCN YTNAARGARAARGGNYTNCCNACNTCNGGNACNAARGTNGARYTNATHAAYMGNYTNATH GARGCNGCNAAYGGNAGYACNCARAGY------GAYGCNGCNATHGAYGAR--------- ------GAYGARATHYTNAARGAYGAYATHGTNCCNGAYGTNCCNAARATGACNCCNATH GTNGCNCCNCARCARACNGAYAAYYTNAAYAAYAGYGGNGTNGARGCNGARAGYACNGAR GARGCNTCNTCNTCNCARTCN--------------------------------------- ---------------CCNGAYTCNTCNGTNGCNAARCCNGCNGARGTNAARATHYTNACN GARGCNGARMGNYTNAARYTNMGNGCNGAYAARTTYGGNATHACNGCNGARAARACNAAR AARGARATGMGNGCNCARMGNTTYGGNACNGCNYTNAGYGARAGYAARTCNGGNAAYATH TCNATGGCNGCNCCNACNGCNAAYYTNGAYAARYTNCARAARMGNGCNGAYMGNTTYGGN GTN------------TCNACNAGYTCNGTNACNGARGAYGARAARAARMGNAARMGNGCN GARMGNTTYGGNAGYAGYTCNGCNACNACNAAY---------AARATHACNYTNAAYTCN ACNGAYAGYGAYYTNGAYGCNAARAARMGNAARMGNGCNGARMGNTTYGGNYTNACN--- GTNCAYTGYAARTGGMGNGGNTGYTCNYTNGAYCCNTGYGAYYTNYTNGAYCAYGTNMGN AARCAYGCNGAYAGYCARATHTCNAARAARTCNTAYGCNTGYYTNTGGAARGARTGYAAR GTNTAYAAYCARCCNGCNYTNTCNGGNTCNTGGYTNGARMGNCAYGTNGTNTGYCAYAGY GGNCAYMGNCCNTAYAARTGYATHYTNCCNAARTGYGGNCARMGNTTYCAYACNCARGCN GCNYTNCARMGNCAYGTNAAYGGNCAYTTYGCNGGNTCNGCNCAYGAYGGNATGAARAAY GGNAARACNMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CCNAGYMGNGTNACNGCNGARYTNYTNGARTCNACNYTNTCNYTNTTYAARGGNAAR TAYGCNYTNATHCARAARCAYYTNGARACNYTNGARGTNGCNYTNGCNACNAGYCARACN YTNAARGAYCCNAARACNAAYMGNYTNGAYAAYYTNGTNGCNAARGARAARAAYATHGTN CARTCNATHGCNGAYATHGARATGGGNGAY------GAR---------------GARGAR AGYGTNTAYCCNTCNGCNYTNACNATGYTNTCNAARATHATHGTNTCNGARYTNGARAAY ACNGAYGAYAAYMGNGARTAYACNGTNGAYGAYYTNATHTAYYTNYTNGTNTAYATHTAY TCNYTNTCNGAYGGNAGYAAYGARAAYCARGCNGARATHAARCARYTNCARGARMGNYTN GTNGAYGTNATHATHAARGAYAARGAYACNYTNTCNCCNGTNGCNCARGGNATHGTNGGN GAYAARGTNAAYGARACNATHYTNGGNGAYCARYTNGARAAYATGTGGGARAARYTNGAR TCNYTNYTNGAYGCNMGNMGNGAYYTNAARCARTTYGGNACNYTNGTNGAYCCNGGNGAY GARATGAGYCCNGCNAGYGTNCARCCNYTNYTNAARCARATHATGGARAARATHYTNGAY CCNGCNAARCCNGARYTNGCNGAYATHGARTGYAARTCNGGNGGNYTNAARGAYYTNYTN AARTCNGGNTTYGGNTTYTTYAARAGYAGYGGNAARCCNMGNCCNGGNGAYGCNCCNATH YTNATGATHTTYGTNATHGGNGGNATHACNACNAGYGARGTNAARCARGTNAARGAYGTN GTNACNAGYGCNAARTCNGGNATHGARGTNATHGTNGGNGGNACNMGNATHAGYGAYATH GARAGYACNYTNATGTCNYTNYTNGTNAAYGAYAAYATHAAYATH--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TTYAAYGAYYTNYTNGTNTCNYTNACNMGNMGNGCNTGYMGNMGNGGNGARAGY ATHAARTAYGTNGTNCARGAYGCNGTNATHGAYTAYATHAARGARCAYMGNYTNTAYGGN TAYCCNGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CCNGAYGAY TGYCAYCAYTTYATHCARTGYGAYTCNATGAARTCNTAYATHATGCCNTGYCCNGGNGAY YTNYTNTTYCAYCCNYTNACNYTNACNTGY---GTNMGNCCNCARGARGCNCCNAARTAY TGYMGNACNCARACNACNACNGGNACNCCNYTNGTNTTYGAYGTNAAYAAYACNTGYGCN AAYAAYGAYYTNCCNGAYGGNATHCAYACNYTNCCNGAYGAYTGYCAYCAYTTYATHCAR TGYGAYTCNATGAARTCNTAYATHATGCCNTGYCCNGGNGAYYTNYTNTTYCAYCCNYTN ACNYTNACNTGY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYGGNCARGTNYTNGTNACNYTNTGY AARGGNCARGGNGGNACNCCNGCNGAYCARCCNATHMGNTCNTGGCAYGAYAGYTGGCAR GTNGTNGCNATGGCNACNAAYGCNAGYTTYYTNYTNMGNCARGTNYTNCCNTTYGAYCCN TCNGAYTTYCCNGARTAYCAYAGYGTNGGNTTYMGNTTYCARGAYAARAGYTTYAAYGTN TCNGGNGCNATHACNCAYGTNTTYGARCARGGNGAYAGYGTNGAYGCNGAYATHAGYGCN ACNMGNGGNATHGTNCAYTAYGAYGGNAAYGAYTAYTCNTGYTCNAARTAYGTNATGAAY GCNTTYAARMGNGAYYTNTCNAARGARACNGGNAAYCCNGTNAGYATHYTNMGNGARATG YTNGARCAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNACNGGNGCNATHGTN CARGCNCARGGNAGYGAYTTYGARAARMGNYTNAARAARYTNCCNGARACNGCNYTNGGN CAYGCNYTNYTNGARTCNGCNCARTCNYTNCAYACNGARTCNYTNYTNGGNCARGCNTGY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGAGYCARGGNGAYCCN ACNTCNTAYTCNGARCCNGARAARTGYGAYATGAARMGNYTNAAYTGGAAYGTNAARYTN GAYTTYAAYGCNCARACNATHAARGGNATHGCNAGYYTNTAYTTYGARAARAARTCNGAY GAY---YTNAAYCARGTNYTNGAYGTNMGNGAYYTNAGYATHGARAAYGTNAARYTNCAR GAYACNAARCARGAYYTNAARTTYAARATHGAYAAYCCNGCNAAYGTNGAYTAYGGNTCN MGNYTNTTYATHGARYTNCCNYTNYTNCARAGYAARAGYTTYACNYTNGAYATHACNTAY TCNACNTCNGCNTCNTCNACNGCNYTNCARTGGATGACNCCNGARCARACNGCNGGNAAR MGNCARCCNTAYYTNTAYAGYCARTGYCARGCNATHCAYGCNMGNAGYYTNTTYCCNTGY CARGAYACNCCNGCNGTNMGNTTYACNTAYAARGCNCARGTNGARGCNCCNAARGARATH ACNGTNYTNATGAGYGCNAAYMGN---------GGNGAYGTNGTNTCNAARCARACNTCN MGNATHACNCAYTTYACNYTNGAYATHCCNATHCCNAGYTAYYTNYTNGCNATHGTNGCN GGNGAYYTNGARTCNMGNGAYATHGGNCCNMGNTCNAARGTNTGGTCNGARMGNGARATG GTNGAYGCNGCNAARTAYGARTTYGCNGARACNGARTCNATGYTNCARGCNGCNGARGGN YTNATGGGNCCNTAYGTNTGGGGNCARTAYGAYYTNYTNGTNYTNCCNCCNTCNTTYCCN TAYGGNGGNATGGARAAYCCNTGYYTNACNTTYGTNACNCCNACNYTNYTNGCNGGNGAY MGNTCNYTNGTNAAYGTNGTNGCNCAYGARATHTCNCAYAGYTGGACNGGNAAYYTNGTN ACNAAYGCNAAYTTYGARCAYTTYTGGYTNAAYGARGGNCAYACNGTNTTYTTYGARMGN AARATHCAYAGYAARYTNTAYGGNGARCCNATG---MGNCARYTNCAYGCNCAYGARGGN TGGYTNGCNYTNAAYAARACNGTNGARACNYTNACNGARGAYGGNCAYGCNCCNTAYACN AARYTNGTNCCNGARYTNTGYGGNGTNGAYCCNGAYGARGCNTTYTCNAGYGTNCCNTAY GARAARGGNTTYGCNYTNYTNGARTAYYTNGARMGNATGYTNGGNGGNCCNGAYGTNTTY AAYAARTTYYTNMGNGCNTAYATHGARCAYTTYAARTAYAARTCNATHYTNACNCARGAY TGGAARGAYTTYYTNTTYAARCAYTTYTCNTCNACNGARGAYCARGARAARYTNGARAGY GTNAAYTGGGAYCARTGGTTYTAYGGNGARGGNYTNCCNCCNTTYACNCCNAAYTAYGAY YTNAGYYTNGCNGARGCNAGYMGNAAYYTNAGYCARMGNTGGATHAGYGGNGCNGAYAAY ------GAYAARTTYTCNGCNGCNGAYATHAARGAYATGAGYAGYGAYYTNATHAAYAAY TTYYTNACNTCNGTNYTNYTNGCNAARCCNGCNGTNCCNYTNAGYACNGTNCARCARATG GARTCNGTNTAYCAYTTYAAYGAYGTNAARAAYTCNGARATHMGNTTYACNTGGYTNCAR YTNTGYATHCARTGYMGNTGGGAYGAYGCNATHGGNMGNGTNATHAGYTTYYTNAAYGAR CARGGNMGNATGAARTTYGTNGTNCCNYTNTAYMGNTCNATGAGYAARTGGGARGARGGN MGNAARYTNGCNTGGAARAAYTTYGTNGAYCAYAARGCNGARATGCAYAGYACNACNGCN AARAARGTNGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGAYAAYCAYGAR GARATHYTNGAYGCNYTNACNGCNYTNGGNAARAAYCCNACNCCNCARGARATHCCNCAR ATHYTNGARCARTAYYTNAARTCNGTNTCNAARAGYGGNGARACNYTNTTYCCNTGGTCN CARYTNAARCCNYTNATHYTNMGNAARATGGARYTNGTNATHYTNGARYTNMGNMGNAAY YTNGCNACNGARAAYATHCCNACNMGNCCNAAYGTNGARAAYGTNMGNTTYGAYGTNATG CAYGCNMGNATHATHGAYTCNYTNCAYAARTTYAAYGGNGCNCCNTTYACNATHCARMGN YTNTGYGARYTNYTNATHGARCCNAARMGNCAYTAYAARMGNAGYGAYAARTTYATGMGN GGNYTNGARAARAAYGTNYTNGTNGTNAGYACNGTNGAYCCNTTYGGNMGNAARGTNGTN TGYGARTCNGGNAAYAARCCNGTNYTNAAYGGNGTNYTN---GAYGTNAAYGGNTCN--- ------------------TAYYTNTCNGTNCCNYTNCCNCCNGTNCCNGGNTGGGTNACN TCNACNAAYACNATHACNTCNCAYAGYCAYAAYTCNCARAAYTCNGAYAARGCNGAY--- ------------------------------------------------------------ ---------GTN------TCNCAYAGYGARTTYACNCARCARGGNGAYGCNYTNCCNGTN CARTCNGARGARGTNGTNGARGARACNGTNGTNACNATGGAYACNGARGTNAGYTCNGAY GTN------GAYGCNGGNGARGCNATGGCNGAYMGNGARGGNGARGAR---------YTN GCNGARGAYMGNGARGCNTCNTTYTCNTCNTCNTCNTCNTCNTCNTCNTCNGAYTCNGTN GARCAYATGCAYATHTCNCCNTTYGGNAAYGARAGYGGNMGNGGNGAYGAYTCNGTNAAR GARGAR------------AAYMGNCCNTGGGCNGCNTTYGCNCARACNTCNAARCARGAY MGN---GAYGAYTCNCARYTNTTYTCNACNAAYAAYCARTCNGARACNGARCCN------ ------------GARGGNAARGARTCNTCNAAYGTNTCNTCNTCNTCNATHCCNACNATH TCNCCNTCNCCNTCNTCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNAAYYTNTTYTAYAGYGGNTGYATHATHGTNGARGTNMGNGAY TAYMGNMGNTCNACNATHGGNTCNTAYCARAGYCAYCAYGTNYTNYTNMGNCCNTCNTCN CARTCNYTNYTNMGNGAYATHACNGCNYTNAGYTGYGAYGGNCAYACNTGGAGYCARGAY GAYYTNTTYCAYYTNGARAGYGARYTNYTNYTNGCNACNGARGARCCNYTNTGYYTNGAY CCNTCNCCNGCNGTNATGTTYATHGAYAAYGCNYTNCARTAYCARGARAARGTNYTNAAY CAYCCNGTNYTNAARMGNGCNGCNAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TTYAAYTCNAARGARGCNTTYGARYTNATHTCNCARTTYGGNYTN TCNTAYGCNATHTTYGCNCCNGGNTGGGTNTAYGARTGYYTNGGNGTNGARTCNTTYACN GAYAAYGARATHAARTTYTGGMGNYTNYTNAARGAYTAYYTNCCNTGGMGNCCNMGNGAR GTNCCNTTYCARACNTCNTTYTGYCARGGNCARGGNCARAARCAYTAYYTNCAYGGNAAR GTNATGAGYGAYMGNCCNTGGCAYAAYGTNGGNYTNCARCARATHCARCCNTGYTAYTCN TTYAAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARTGGGGNGAYTCNGGNCCNYTN CAYCCNAARCAYYTNMGNGARGCNGTNMGNATHYTNCAYGARAARGGNAGYATGCCNTCN ACNAARAGYAARAARCAYYTNTTY------------GCNGCNACNAARGTNAAYATHCCN AGYGCNAAYAARYTNGGNGCNATHCCNGCNATGGTNACNGGNGAYCCNACNAARATGACN MGNGGNYTNATHGTNYTNCARGARTGGTGGGGNATGAAYGAYCARATHCARGAYTGYGGN AARGARYTNTCN---GCNCARGGNAAYYTNGTNACNGTNGTNCCNGAYYTNTAYMGNGGN AARGTNACNAARGAYAAYGARGARGCNGGNCAYTTYATGGGNGAYYTNGAYTGGAARGGN GCNGTNGAYGAYATHCARGGNGTNGCNMGNTAYYTNAARMGNCARGGNGTNAARAARGTN GCNGTNACNGGNTTYTGYATGGGNGGNGCNYTNTCNYTNGCNGGNGCNGCNYTNGTNCCN GARATHGAYGTNGCNGTNCCNTTYTAYGGNATHCCNTCNGCNGARYTNTGYGAYGTNACN AARATHAARATHCCNYTNCARTGYCAYTAYGCNYTNAAYGAYGARTCNGCNGGNTTYGCN TCNCCNGCNGARTGGMGNCCNYTNAARGARAARYTNACNAARGCNATHAARGTNYTNGAR TTYTAYGARTAYGAYGCNGGNCAYGCNTTYACNAGYAARACNAGYCCNAAYTAYAAYAAR CARTGYTGYGAYYTNGCNTTYACNMGNATGTTYGARTTYYTNAARAARCAYYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TCNGCN ACNGAYYTNAGYAAYGTNTGYCAYYTNATHGCNGARAGYTAYTAYCARGAYAARGCNATH AARTCNGAYGARGTNGTNGAYTCNTGGTCNYTNGARGARTGGTGGCARGTNAARGCNTTY YTNYTNAAYGTNATHAARCARGCNGTNMGNCARGARTGGACNCARGAYAARATHACNTCN GARYTNGGNCCNATHACNGARTCNYTNAARACNGTNATHGCNGAYGCNATHAAYATHCAY MGNGAYTCNTTYAARMGNAARYTNYTNCARAAYACNACNGCNATHTCNCAYGCNGTNYTN TCNGAYTTYGAYTGGAARYTNCARYTNGCNYTNTCNAGYGAYAARATGTCNAGYYTNCAY CARCCNYTNGTNTCNYTNGGNYTNGAYATHMGNCARGCNGAYGGNCARAARAARCAYGTN AAYYTNGARATGGAYAARGCNGARYTNGCNMGNYTNATHGGNTCNYTNGARCARTGYAGY AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYTCNGARTTYYTNGGNGARYTNGGNCARGAR GCNAARATGGTNATGYTNCARTAYTCNCARACNTTYAAYGARAGYGARCAYTAYGARCAR CARGGNYTNCARGCNGTNAARGAYYTNTCNGCNCAYGCNGCNTGYYTNGARCARMGNYTN AARYTNCARAARGARATGYTNTGYAAYMGNYTNCARGTNATHACNCAYAAYYTNAARGTN GARYTNCAYGGNAAYCAYGGNCAYGGN---GAYGGNAARCCNYTNGARTTYGCNTCNGAR GTNCAYAAYAARGAYCAYATHYTNGARCAYYTNCARAAYGTNATHTCNACNAARCCNAAR GARCARATGACNGAYGARGARYTNGARTTYCAYTAYTTYAARYTNCAYGAYTAYGAYAAY AAYAAYAARYTNGAYGGNGTNGARATHGGNAARGCNYTNACNCAYTTYCAYGAYGARGGN GTNCAYGGNAGYAARAARYTNGGNAARGAYGAR------------ATHCCNGTNGCNTCN GAYAARGTNYTNTCNACNTCNGTNGAYACNGTNYTNMGNAAYTAYGAYAARGAYGAYGAY GGNTAYATHTCNTAYTTYGARTTY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARTTYGCNGAYAGYGTNGCN TCNATHGARACNGAYGAYTTYATHCCNGCNTCNTTYAARTCNTCNGGNGCNMGNGTNAAR ACNGAR---CCNTCNGAR---YTNYTNCARTCNCAYGAYGARGCNATHTTYGGNTCNYTN TCNACNGTNGGNTTYACNATHAARCCNGAYATHGAYGTNAARCCNGTNTCNATGGAYGCN GCNTCNATHATGCAYCCNMGNYTNTTYTGYAAY--------------------------- ------------------------------------------------ATGGAYATHGTN GTNGTNGGNAGYTGYATGACNGAYYTNATHAGYTAYGCNCCNMGNYTNCCNATGGTNGGN GARACNYTNACNGGNCAYAARTTYACNGTNGGNTTYGGNGGNAARGGNGCNAAYCARTGY ATHACNGCNGTNMGNYTNGGNGCNCARGTNGCNATGGTNGGNAARYTNGGNGAYGAYACN TTYGGNCAYGAYTAYYTNAARAAYATGGARAARCAYAAYGTNAAYTGYGAYCAYYTNCAR ATHGTNCCNGAYGTNTCNAAYGGNGTNGCNTCNATHYTNGTNGCNGCNAAYGGNGCNAAY TGYATHGTNACNGTNCCNGGNGCNAAYAAYCAYYTNACNGTNAAYGAYGTNAAYGARGCN GARCAYYTNATHAARAAYTGYMGNGTNYTNGTNTGYCARAAYGARATHCCNCAYGARATH TCNGTNGCNGCNATGAARYTNGCNAARAARCAYAAYGTNAARGTNGTNTAYAAYCCNGCN CCNGCNTCNCARGCNYTNMGNTCNGARYTNTTYCARYTNCCNGAYTAYTTYTGYCCNAAY GARACNGARGCNGARATGATHACNGGNATHCCNGTNAARTCNATHACNAAYGCNATGAAR GCNTGYAARATHYTNCARGARAGYAARGGNTGYAGYTCNGTNATHATHACNYTNGGNGAR TAYGGNGCNGTNTTYAARGCNTCNACNGAYGTNGAYGCNGTNCAYATHGTNACNACNCCN GTNAARGCNGTNGAYACNACNATGTCNTTYCCNGGNMGNACNCCNATGGCNATGCCNGGN ACNATGCCNGGNATGGCNCCNMGNATGATG---ACNCCNGGNTAYGCNTTYACNTCNATG GGNATGACNMGNATGAAYCCNATGATGCCNATGCARATGGGNATGATGGCNCCNATGATG CARCCNATGATG---CARCCNCARATGCARATGCARCCN---CAR------ATGAARCAR GCNCCNMGNTTYATHCCNCARGAYTTYTCNAARACNGGNACNACNGGNGARMGNCCNCCN GTNACNACNGTNTTYGTNGGNAAYATHAGYGARMGNGCNCCNGAYATGATGGTNAARCAR ATGYTNCARMGNTGYGGNAAYGTNYTNAGYTGGAARMGNGTNCARGGNGCNTCNGGNAAR YTNCARGCNTTYGGNTTYTGYGARTAYGARGAYCCNGARGCNACNYTNMGNTGYATHMGN YTNYTNAAYGAYTGGTCNATHGCNCARAARAAYYTNGTNGTNAARGTNGAYGCNAARACN AARACNYTNYTNGAYGARTAYMGNAARAARAARCARGCNTCNGCNGARTCNACNGAYAAR AARGAYACNGAYGCNAARAGYGARAARAARGARGARAAYGGNGARGAYAARGAYACNGAY TCNGARAARGGNGARAARGAR------------------AAY---GGNYTNGAYGARAAY ACNCARMGNGARGAYMGNGTNGCNCAYGCNGGNYTNGARGCNATHATGMGNGARTAYGCN TTYGARYTNAAYAARGARCCNGCNAARTCNTCNGAR---CCNGTNCARGARAARAARGAR CARCARCCNAARAARGARAARGAYATHTTYATGCAYGCNAARGAYACNGGNTTYGARGAY ATGGARATGGARGAYGARAARMGNCARATHATHAAYMGNGARATHAAYAARTTYMGNGAY MGNCAYAARGAYGCNGAYGARGCNAARGARAARGAR------AAYAARGARMGNAGYYTN GCNMGNGARMGNGARMGNMGNCARGARGARAARMGNCARMGNGARMGNYTNGARAARATG MGNATHGARMGNGAR---------------------AAYMGNCARAARGARMGNGTNAGY GTNMGNGTNTCNMGNTCNAARTCNMGNTCNGCNTCNCCNGCNCCNTCNMGNTCNMGNMGN MGNTCNMGNTCN------------MGNGAYMGNAAYAGYMGNGAYMGNTCNMGNGARMGN AARAARGARMGNGARATHGARGARGARGARGARYTNTAYGARMGNMGNAARYTNGARAAR AARYTNMGNGARAARGARGCNGCNTAYCARGARMGNYTNAARAAYTGGGARGGNMGNGAR MGNAARAARGCNMGNGARTAYGARAARGARAGYGARMGNGARGAYGARMGNAARGTNGAR GARACNMGNGARGGNMGNMGNYTNAARGARTTYYTNGARGAYTAYGAYGAYYTNMGNGAY GAYCCNAARTTYTAYAARGGNAGYGCNYTNCARMGNMGNCARAARGARMGNGARAARGAR AARGARYTNGAYAAYMGNGAYMGNCARMGNGARAARGARGARTTYGARGARATHAARMGN AARYTNTTYGAYGARGGNCAYCCNGAYGCNGARACNGARGTNGCNMGNATGGARMGNGAR MGNGARGARCAYYTNCARCCNCARYTNAARYTNCCNGARCCNAARCARCCNTCNCCNCCN CAYAAYAGYCAYGARTCNGAYTCNGARAAYTCNMGNCARGCNGAYACNMGNYTNTCNCCN ---------------------CCNAARCCNCCNGARCAYAAYTCNTCNACNAARAAYAGY CAYCCN---------------------------------------------GARCAYMGN AAYTCNCCNTCNYTNTCNACNTCNCCNATHTCNACNGAYTCNMGNGTN---AGYGCNCCN GGNYTNTGYYTNGAYGARTCNTCNCARTCNTCNYTNCCNTCNGTNCCNYTNCCN---ATG TCNCARGARGAR---AAYAARGTNGGNATHAARTCNTCN--------------------- TCNAARMGNYTNGCNCCNGTNGTNAGYCCNGAYTCNTCNAGYYTNCCNGGNCCNACNACN GCNTCNGAYGGNAARMGNAARAARYTNACNGTNGGNGAYGTNTTYAAYCARGAYGAYGAY GAYAGYAAYGARCCNAARAARMGNAARYTNATHCCNYTNGAYTAYGAYGAYGAYAARTCN AGYCCNACNGARAARAARGGNTCNACNGCNGARGARAARMGNCARMGNATHAARCARYTN ATHGARAAYATHCCNACNGCNAARGARGARYTNTAYGCNTAYACNGTNGAYTGGGAYATH GTNGAYCARGCNYTNATGGAYAARMGNATHAARCCNTGGGTNACNAARAARATHGTNGAR TAYATHGGNGARGARGARCCNACNYTNACNGARTTYATHTGYTCNAARGTNGTNGCNAAR AGYACNCCNCARAGYATHCARAAYGAYGTNGCNATGATHYTNGAYGARGARGCNGARGTN TTYGTNGTNAARATGTGGMGNYTNYTNGTNTAYGARACNGARGCNAARAARATGGGNYTN GTNAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CCNGAYTTYAGYTTYGAR MGNATGTCNTGGATHAARCCNAAYTTYATGTGGATGATGTAYMGNTGYGGNTGGGCNCAR AARGCNAAYCARGARMGNGTNYTNGCNATHTGGYTNACNMGNGCNGGNTTYGAYCAYATH YTNGCNACNGCNAARYTNGGNGGN------GARGGNGAYGCNGTNTCNMGNAARTCNGAY GARGTNMGNATHCARTGGGAYCCNGAYCAYGAYCCNCAY---GGNACNTCNGTNCCNMGN MGNGCNATHCARYTNGGNYTNMGNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNMGNGGNTTYATHCCNAARMGNMGNCCNATHGCNMGNYTNGGNCARTTY GGNACNACNGGNMGNTTYTGYYTNATHGTNGAYGCNGARAGYTGYYTNGAYMGNYTNTAY GGNGGNTAYTAYTCNGAYTGGGTNTGYGGNGGNCARTGGAAYMGNATGACNGCNTTYYTN ACNAAYYTNGTNCARGCNTGYCAYAAYGGNAAYATGGARYTNGTNGTNTAYTTYAAYGGN GCNYTNGARAAYCARAARATHAAYGAYTGGATGTCNCARCARYTNTCNCARMGNGAYAAR GTNMGNTAYGTNYTNMGNCAYATHGCNAAYAARGGNACNCCNCCNCCNAARATHTGGTGG AAYCARCCNGTNTTYYTNAARGARGCNYTNAARATGGCNYTNMGNCARYTNGCNGTNACN ATHGCNTGYTCNYTNGAYGAYCAYCARYTNGARGTNATHAAYATGTGYMGNGARCAYACN YTNCARGGNATHYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATGGCNGAYGAYTCNGAYATHCCNCCNYTNGARGAYATGACNGAYATHYTNCAR AARGCNGARYTNATHMGNGARCAYMGNAAYCARGAYAARAAYAGYACNCCNMGNAARATH GARACNGARGAYGCNAARAARMGNGCNAARGTNACNAARAARACNTCNGGNGTNTCN--- ------------------AARCCNGTNGCNCARACNGARCARAAYGCNAGYGAYYTNCAR MGNTCNAARGAYGARACNAARATHGTNCCNGAR--------------------------- ------------AARACNAARACNGCNAGYCARGGNATGTTYGGNGGNATGAARAARGGN TTYYTNTTYGGNGGNCCNAGYAARAARCCNYTNAARACNACNGCNAAYGGNAGYYTNAAY CARCARACNTCNAARATHCARACNGGNGARACNGTNTCNTGY------------------ ACNGCNACNAARTCNACNAARGARGAYYTNACNTAYATHTCNCCNTCNGGNAARACNGAR TCNGGNYTNGCNTTYAAYGARGTNCARCARGCNATGTCNGARGCNAARGGNYTNYTNGAY AAYCARGARTGGATHACNGAYGAYTTYYTNAGYAARATHGARAARAAYGARTCNYTNYTN AARMGNTTYAGYGAYCCNCARTTYATGTCNGCNYTNCARGAYTTYCARACNAAYCCNCAR GCNGCNATGGCNAARTAYAARGGNAAYACNGARGTNGARAARTTYYTNATGGARTTYTGY GGNGTNYTNGGNGAYCAYTTYACNAARYTN---------GGNGAYAAYGARACNGCNACN GAYGCNAAYAARAARTCNAGYCARCARTCNACNGCNGCNCCNAAYGTNYTNAAYAARTCN ACNTCNCARAARGTN------------------------------GARAARCARTCNCCN AARATHGTNGARATHAAYGAY--------------------------------------- ---------------------GGNGAYAAYGAYAAYGTNMGNYTNCARTCNAAYCAYACN TCNTCNGAYGCNTAYGTNAARACNTCNCAYACNACNGARAARGGNAARGCNTCNATHCAR ATHCAYGAYCCNCARAARCARGCNGARATHCARGARATHAAR---------------CAR ATGGARGAYGARGAYGTNAARCARGTNYTNAAYGAYCCNAARGTNATGGARACNYTNATG GAYCCNAAYATHATGGCNYTNATHMGNACNYTNAARGARGAYCCNGARAARGCNCARAAR YTNATHGAYAAYGCNGAYGCNGAYTTYAARAARAARATHCARYTNYTNGTNTCNAARGGN YTNYTNCARTTYCARATGAAYCARAAYMGNTCNAARCCNACNAAYGTNCCNTCNYTNYTN YTNCARGAYCAYGARAAYGAYGCNYTNTTYCARACNYTNGGNMGNYTNTGYGTNACNYTN GCNACNGGNGTNGTNCARYTNTAYYTNGCNGAYCARCCNGAYMGNACNMGNTGGAAYAAR MGNTGYTGYGGNGTNGCNTGYTTYGTNAARGAYAGYCCNAARMGNTCNTTYTTYATHAAR GTNYTNGAYATHAARAARCARCARGTNYTNTGGGAYCARGARYTNTAYAAYCARTTYGTN TAYAARACNCCNMGNGARTAYTTYCAYACNTTYGARGCNCARAGYTGYCARGCNGGNYTN AAYTTYGCNTCNGARGAYGARGCNATHAARTTYAARGARGCNGTNGARGGNAARYTNAAY GARMGNMGNCARAARAARATGGAYMGNAAR---------------CARAARGTNTCN--- ------AAYMGNGGNACNGTNAAYCARGGNCARCCNCCNCARMGNACN---GGNCCNAGY GCNACNCCNAGYCCNGCNCCNACNAGYGTNGARTCNAAYMGNCCNGCNATHAAYACNGCN AAYCARAARAARGARAARGARAARAARAAR------GAYGGNAARAARAARYTNACNAAR GCNGAYATHGGNACNCCNTCNAAYTTYATHCAYATHAGYCAYGTNGGNTGGGAYCCNGAY AARGGNTTYGAYATGAAYAAYYTNGARCCNGAYATGAARACNYTNTTYCARTCNGTNGGN ATHAARCCNGARGAYAAYGTNGAYAARGARACNYTNGAYTTYATHTAYGAYTTYGTNGAR AARCARGGNGGNATGGARGCNTTYAAYAARGARYTNMGNAGYAAYGAR------AARCAR CCNCCNCCNCCNCCNCCNGCNAAYATGCCNMGNGGNGGNCARCCNCCNCCNCCNCCNGCN MGNCCNGGNGGNGCNCCNCCNCCNCCNTCNMGNGCNCCNCCNCCNCCNCCNCCNCCNCCN TCNMGNGGNGGNGCNCCNCCNAAYATGMGNGGNGCNATHCCNCCNCCNCCNCCN---MGN AAYATGGGNGCNGCNCCNMGNGCNCCNGCNGCNGCNCCNCCN------------------ ---CCNCCNCCNCCNCCNCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYYTNGTNTCNCARGARCCNTAYGCNCARTTYAAYGCN TGGTTYGARGARGCNAARGCNACNCCNGGNATHATGGARGCNAAYGCNATGTCNYTNGCN ACNGCNACNAARGAYGGNATHCCNTCNGTNMGNATGGTNYTNATGAARGGNGTNTCNAAR GAYGGNATHGARTTYTAYACNAAYTAYAAYAGYMGNAARTCNCARGARYTNATHGAYAAY CCNCARTGYAGYYTNATGTTYTAYTGGGARCCNYTNATGAARTCNGTNMGNATHGARGGN AARGTNCAYAARYTNTCNGTNGAYCAYTCNAGYAAYTAYTTYCAYTCNMGNCCNMGNTCN AGYCARATHGGNGCNTGYGTNAGYGARMGN---CARAGYTCNGTNATHCCNTCNMGNGAY GTNYTNGAYAARMGNAARGARGARYTNGARYTNAARTAYAGYGAYGARTCNGTNGARATH CCNAARCCNGAYTAYTGGGGNGGNTTYMGNGTNGTNCCNCAYAARTTYGARTTYTGGCAR GGNCARACNAAYMGNATHCAYGAYMGNATHGTNTTYMGNAARYTNAAYGARGGNGARGTN ATHGAYTCNTCNGTNACNTTYCAYGGNYTNGARGGNTGGGTNTAYGARMGNYTNCARCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TCN MGNTAYTCNCCNYTNCARTCNTTYTCNMGNCAYTTYMGNAGY------MGNAARACNAAR YTNGTNAAYAAYTCNAAYGGNGGNAAYTCNTCNGGNACNCAYTCNYTNGCNAARTCNGCN GTNTTYGTNACNGGNGTNTGYGGNTGYAAYTTYYTNGGNGCNATGATHTGGAAYTAYGAR AAYGTNMGNCARACNTAYAARGARYTNGCNAAY---GARGGNTCNGCNCCNMGNCAYCAY MGNTTYATHCAYGARAARGTNTTYGGNTTYMGNAARCAYYTNAGYGCNGTNTGGGCNAAY YTNGAYGCNTCNACNAARYTNACNTTYGGNATHGTNGTNGCNAAYGCNGCNGTNTGGYTN YTNTGGAARGTNCCNMGNYTNCARTAYACNATGATHAGYTAYTTYTCNTCNGCNGCNGCN CAYCCNMGNACNTCNATGATHYTNAGYAGYTTYAGYCAYATHAAYTTYTTYCAYYTNGCN ATHAAYATGTAYGTNYTNYTNTCNTTYGCNCCNGTNGCNGGNAARATHTTYGGNCAYGAR CARTTYTCNGCNTTYTAYYTNAGYGCNGGNACNATGTCNGCNTTYGTNAGYATHGCNTGY CARCARYTNYTNAARMGNCCNYTNGCNATHTCNGTNGGNGCNTCNGGNGCNATHATGGGN YTNYTNGGNGTNACNGGNGTNGTNTAYCCNAAYGCNCARYTNCARATHGCNTTYGTNTCN GARATHTTYCCNCAYTCNTTYTCNGCNGARTCNGGNATHAARGCNATHATHYTNTTYGAY YTNYTNGGNYTNTTYATGGGNTGGAARGTNYTNGAYCAYGCNGGNCAYYTNGGNGGNATG YTNTTYGGNATHYTNTAYGCNAARTAYGGNAAYAARTAYATHTGGGGNGARMGNGARTCN ATHGTNAARTTYTGGCAYAARTTYMGNGGNCARCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TTYAAYCARCARATGAARGCNAAYGARGCNCARYTNGARGCNATG AARMGNCARAARGARGAYMGNCARAARMGNGARGARGARGARATGGTNGCNCARYTNMGN CARGARGCNGTNCAYAARGCNACNGGNATHAARNNNTAYAARGCNGTNAAYCCNCARCCN AGYGAYAARGTNYTNACNACNGCNGARTCNCCNTGYYTNMGNACNAARYTNMGNTCNCAR MGNAAYTTYAGY---CAYCAYGGNTCNAARACNGAYAARCAYGGNGGNGTNCCNATGGGN GTNCCNAAYCAYTTYTGYGAYGAYGCNACNAAYTTYACNTCNATHGAYTGGAAYAAYGCN TCNACNGARGARTAYACNTGYCAYGGNGGN---------------ATHGAYYTNGAYATH YTNMGNGAYAGYTAYCARAGYTGYGARAARMGNGCNAARAGYCCNATHCAYGTNTGYTTY CCNCAYGTNATHCAYTAY---GARGARATHCCNACNAGYGGNTCNCAYMGNCCNYTNTGG CCNAARTAYGGNGARTAYACNTAYYTNCCNCCNCARMGNTGGGTNCAYTCNYTNGARCAY GGNTCNGCNGTNTTYYTNTAYAAYCCNTGYGCNAAYCCNGARCARATHATGAARTTYAAR GCNGTNGCNMGNAGYTGYYTNMGNMGNCAYATHATHACNCCNAGYAARMGNATHCCNCCN CCNCAYATGTTYGCNATHGCNACNTGGAARTGYAARYTNGTNATGACNCAYCCNGGNGTN GCNGARATGGTNGAYTTYATHMGNACNCAYGCNATGCAYGCNCCNGARAAYGGNGCNATH TCNGAYGGNCARTAYAARCARGCNYTNACNAARCCNGCNCARATHGTNAGYGAYYTNAAR GARTCNAAYATHTGYCCNCARATGTCNATGYTNGARTGYGARCCNTTYGAYACNAAYAAR AARACNCARATHGAYGAYGTNYTNATHCCNGARYTNCARGAYGCNATGGTNMGNGTNGCN MGNATHMGNAARAAYCARGTNCCNAARTGYGTNAARGARGCNCAYGTNATHGCNTCNTGY TAYGTNAAYTAYTAYAGYAARGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARGAYGARGTNCARACNYTNYTNACNTCNAARGTNTCNCCN CARYTNAARGARGARGTNACNGAYACNYTNMGNGARATHAARYTNAARAAYYTNYTNAAR AARGCNGTNTCNAARTCNAARAARCCNGGNAARACNGGNYTNCARCARGARGTNGARGCN GCNYTNGCNMGNTCNGCNCARYTNYTNGARAARGTNACNMGNGAYGAYATHYTNTCNGAY GTNAGYGAYGTNAGYYTNTCNACNCARYTNYTNYTNACNGAYGCNGGNAGYAGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TTYGTNGGNMGNGAR GGNCARGTNGCNTGYTCNYTNTCNAAYAARGTNTAYGTNTTYGGNGGNGTNGARCARGGN CARGGNGARGARCCNAARGARACNAAYGARYTNYTNGTNTTYGAYATHGCNTCNCARACN TGGTCNAARCCNGTNGTNTCNGGNTCNCCNCCNCCNTCNMGNTCNGCNGCNTCNYTNGTN GCNGTNGGNACNAARYTNTAYYTNTTYGGNGGNYTNAGYCAYATHTGYGGNTGGTTYGAY GAYGTNCAYACNTTYGAYACNGTNACNAARACNTGGTCNATHATHGARACNGAYGGNTCN AARCCNMGNGCNMGNGAYAARYTNCARGCNGTNGCNATHGAYACNAGYATHTAYTAYTTY GGNGGNTTYGGNCCNAARTCNGAYGARGCNGARGTNGAYGAYYTNGCNGGNGAY---GAY GAYGAY---GARGAYTTYGARGAYATHCCNGARAGYMGNGARCARGAYGGNGCNGARTTY GGNTGGTTYAAYGAYYTNTGGATHYTNGAYACNYTNACNYTNAARTGGTTYCARCCNATG CARATGAAYYTNGGNGTNCCNAGYGARMGNGCNGCNCAYGGNATGTGYGCNATHGGNMGN AARYTNGTNATHTTYGGNGGNMGNGAYAGYGARAAYMGNCARAAYGAYATHCAYATHTTY AAYATHGAYACNAARAARTGGGARGCNGAYYTNAGYTTYAGYGGNCARACNCCNGCNCCN MGNTCNTTYCAYACNYTNACNGCNGTNGGNAAYAARGCNGTNGTNTTYGGNGGNMGNGGN MGNGAYAAYAAYCAYTTYAGYGAYTTYGAYATHYTNGAYYTNGARAARAARGARTGGTCN MGNGCNTCNGTNGARGGNTAYCARCCNCCNGCNMGNGGNCARCAYTGYTCNYTNGTNGTN GGNGAYGAYTTYYTNGTNTTYGGNGGNTCNGGNAAYTTYAGYGCNGARATHATGCAYTGY CARACNTTYTAYACNGAYACNTTYYTNTTYAARACNGAYTCNATH------TCNAGYGCN AARAGYAAYGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TCNTAYATHAARAAYTCNTCNTCNCARGTNYTNGGNCCNTCNYTN GTNTAYCCNCAYATHCAYCCNTCNCARYTNATHGTNCCNTCNGGNGARAARACNTAYGAR YTNATHGGN--------------------------------------------------- CCNGARACNCARAAYGARGARYTNGARGARCAYAARATHTCNACNTGGMGNGARGTNYTN MGNGGNMGNCARAARCCNTTYGTNTAYATHTCNCCNGAYGCNAGYYTNTTYGAYGCNATH AARAARYTNATHGAYAAYCARGTNCAYMGNYTNCCNGTNGTNGAYGARACNACNGGNAAY GCNYTNTAYATHYTNACNCAYAARMGNATHYTNMGNTTYATGCAYYTNTAYTTYAARGAY YTNCCNCAYCCNGCNTAYATGMGNAARTCNATHAARGARYTNGGNATHGGNACNTAYGAR AAYGTNATHACNGCNACNYTNGAYATGACNYTNATHATGGTNYTNAAYYTNTTYTGYAAY CAYMGNATHTCNGCNYTNCCNGTNGTNGAY---AAYCAYGGNAARATHATGGGNATHTAY GCNAARTTYGAYGTNATHAAYYTNGCNGCNGARAARACNTAYAAYAAYYTNGAYATHACN YTNMGNGARGTNYTNGGNGGNAARAAYGAYAAYAAYTCNGARGARGGNGARAAYGTNGTN TCNTGYYTNCCNACNGAYYTNYTNGARACNGTNYTNGAYAARATHGTNAARGCNGARGTN CAYMGNYTNGTNGTNGTNAAYAARGARGGNGGNGTNGARGGNATHATHTCNYTNTCNGAY YTNYTNAAYTAYACNGTNYTNMGNCCNATHGAYGAR------------------------ ------------------------------------------------------------ ---------------------------GGNMGNMGNMGNTTYCAYGGNGCNTTYACNGGN GGNTTYTCNGCNGGNTAYTTYAAYACNGTNGGNTCNAARGARGGNTTYACNCCNTCNACN TTYGTNTCNTCNMGNAGYCARAARTAYGAYGAYGAYMGNTCNTTYMGNCCNGARGAYTTY ATGGAYGAYGARGAYYTNGGNGARCAYGGNATHGCNCCNMGNAARTTYGCNACNGCNGCN AAYTTYACNTCNGARGARMGNAARMGNAARGTNGARGAYGTNGCNACNAGYYTNACNGCN TCNTCNACNYTNAAYYTNGGNAAYACNYTNAAYGAYYTNGTNATHCCNCARTAYYTNCCN ATHGGNATHAARYTNYTNMGNAARATGGGNTGGMGNGARGGNCARGGNYTNGGNCCNMGN ATHAARACNAARAARAARAARAARGCNGAYGCNTCNTCNACNGCNGCNGCNMGNATHTAY GGNTGYGCNMGNCCNCCNTCN---TCNTCNGAYTCNGAYTCNGAYAAYTTYYTNCCNTCN AAYATGGCNGAYATHACNTTYGCNCCNAGYGAYGTNAGYCCNYTNACNYTNACNGCNAAR AAYGAYGTNAARGGNYTNGGNTAYMGNGGNYTNGAYTCNTCNYTNGCNYTNCCNACNGCN CAYGTNAAYYTNTTYAGYGARCCNGTNMGNGTNAARGGNMGNGGNAARGCNATHMGNGGN CARGCNTTYGGNGTNGGNGCNYTNGARGAYGCNGAYGAYGAYGTNTAYGGNATGGAYAGY ATHGCNAAYTAYAAYACNACNYTNMGNGAYGAYGAYGAYGAYAAYGAYGGNCAYTTYGGN TGGACNGCNCCNMGNTCNCAYGGNAARCARAARGTNCCNGTNTCNTAYGTNGGNAARYTN YTNGARGGNTTYACNYTNTCNTCNAARCCNYTNAARCCNTCNAARMGNTTYCCNCCNCCN GTNYTNCCNGCNGGNTTYAARCCNTTYCAYTGGACNMGNMGNMGNAAR------------ ---AARAAYGARGGNGARGCNACNCAYGGNYTNAAYGCNGTNGAYMGNGGNYTNYTNYTN GAYGARAARCCNATHATGGARTCNGTNTTYGAYYTNGTNCCNGCNGCNGAYAARAGYMGN GTNGCNGCNACNCARGARGCNATHMGNATGACNCARTCNYTN------------------ CARTCNAARCARTCNGAYCAR--------------------------------------- ---GARGTNGARAARGTNGTNGARAARCARAARTCNATHGGNCCNTCNTTYGTNTCNAAR TTYACNCCNGCNGTNGARGAYCCNGARGAR---------------------ATHCCNGCN TCNAARCCNACNACNTTYTCNACNTCNTTYTCNGTNMGNCCNTTYCAYAARGAYCCNGTN AARCARGGNMGNTTYGAYAGYTAYYTNGCNAAYGTNCARGARMGNYTNTCNGAYCCNTAY ACNTCNYTNTCNACNAAYGAYATGACNGARTGGGARMGNGCNMGNGARAARGARGARTTY ACNMGNTCNGCNAARYTNTAYMGNCCNATGTCNGCNATGATGGCNTCNMGNTTYGTNGAR GGNTCNATGYTNGAYGAYAARACNGARGARMGNGAYACNAARGTNAARGAYGTNTGYACN GAYGARTTYAARGCNGTNGARATGMGNATGTTYGGNAARYTNACNMGNGARGARGTNGAR TGGCAYCCNGAYAARYTNGTNTGYAARMGNTTYAAYGTNCCNAAYCCNTAYCCNGGNTCN GAYATHGTNGGNYTNCCNAAYGTNAARMGNGAYAARTTYTCNATHTTYAAYTTYYTNAGY ATHGGNGAYTTYMGNCCNAARGAY---CCNGTNCCNACNCCNGCNCCNGAYAARGARGAY GARMGNGAYGCNGARACNCCNMGNGGNGAYGCNGAYYTNAARMGN------AARAARAAR GCNACNYTNTCNTCNATHTTYAARGTNYTNGAYGAYCCNGAYTTYCAYCAR--------- ---------AARMGNAAYACNTCNYTNCCNATHACNCARGAYAARCARGARAARTCNGCN CARGARGARAARGARGARGARGARGARGTNGAYGAYGARGARGAYGTNGAYYTNTTYMGN GCNATHTTYAARAAYTCNGAYTCNGARGAYTCN------------------GAYGAYAAY GGNGCNGCNGTNATHTCNGAYGAYTCNYTNAAYGARTCNATGGAYGGNATHAARGAYGGN CARATHGARGAYAAYAGYAAYGARCAY---AGYGGNATGGAYMGNCCNACNAARTCNAGY GARTGYTTYGGNTCNGAYGARGARAARAARGARACNTCNCCNCARCARCAYYTNGARGAR GTNGAYGGNAARCCNCARGARGCNTCNTCN---------CCNCCNCAYAGYCCNCCNGAY AARAGYCCNCCNGTN---GGNMGNCAYTCNMGNTGGGAYAAYMGNCCNAARTCNATHTTY AGYGTNYTNGAYCARYTN---------------AAYACNAAYCCNGCNACNTCNGAYCAY CCN------------------------CARGAYGAYACNGAYGARTAYGGNCCNTCNYTN CCNCCNCCNCCNCCNTCNTCNCCNTCNCCNTCNYTNCAYAARGGNATHGAYAAYAARAGY MGNCARAARGARAGYTGGMGN------GARACNAARGARMGNAAYTCNMGNGARAARMGN AARAARGAYAARAARMGNAARTCNMGNCAYAARAGYAARAGYAARAARGARAARAARTCN AARAARTCNTCNAARTCNAARAARTCNMGNMGNGAYAGYTCNGGNAGYGAYGCNGAYACN GARTCNAGYGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNATHCCNTCNAGYGARGARGGNTGG MGNATHGCNACNCARGTNYTNAARGARAGYGGNGGNYTNYTNCAYATHCAYCARAAYGTN ACNGTNGARCCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARYTNGARAGYGTNMGNGCNTAY TAYGGNYTNMGNMGNGAYATGYTNGARMGNATHACNCAYMGNGARGARYTNTTYAARAAR ATGGTNGARTTYGAYACNAARGCNAGYGAYCCNAAYMGNTTYTTYAAYGAYMGNGGNGGN AARYTNYTNCARGARGARAARCARMGNAARAARGTNYTNAARGAYYTNCCNAARYTNGAR GARGARATHGCNGARTTYATHGTNAARCARGARCARGCNACNGGNAAYGARTTYTAYGTN AAYGGNYTNMGNTTYCCNCARTAYGTNATHMGNCARTGGGARGAYTTYCAYTCNAAYAAR GARAARGAYAARGTNGAYMGNATGAARGCNMGNGCNAARCARACNCARGARGARATGATG TTYGGNAGYAARTCNGCNATHTGYACNCCNGGNAARMGNAAR---CCNGGNGCNTCNACN CCNATGMGNACNCCNYTNAARGCNMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CARGAYGTNCARGGNGTNCARGARGCNCARAARGARTGYYTNAAY GARTTYMGNTCNCARYTNYTNACNYTNACNGAYGCNYTNCARTCNYTNCARATGGCNACN GGNCARTCNTCNGARATGGAYGARGARGARAARYTNAARYTNGAYCARYTNTCNACNYTN YTNGGNGTNCCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGTNGGNTTYATHGTNCARAGYTCN AGYYTNAAYTCNTTYGGNTCNATHTGYTAYTGYATHATHGTNYTNGGNATHCAYATHTAY GCNAGYTAYAARGAYATHACNMGNTAYCARGAYGCNMGNGAYMGNGCNTGGCCNAGYAAY TGYGGNGAYCCNCCNTCNGARGTNTCNCAYYTNYTNGCNTGGACNATHATHTCNYTNYTN ATHATGCCNATHTTYTGYGTNACNGCNTTYATHAARGTNGGNAAYYTNGCNAAYGAYGGN GTNAARYTNGGNMGNGAYCARAAYGARMGNCCNACNGGNGAYAAYGARGAYTCNACNAAR AARGGNAARGAYGARCAYAARAARAARYTNMGNTAYYTNTGGAARCAYTTYTGYCCNGTN GCNCARACNYTNCAYYTNYTNGCNGCNTTYYTNYTNYTNYTNCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AGY TAYCARGGNGAYGGNGCNGCNGTNYTNYTNMGNGCNYTNGARCCNATGGARGGNCAYGAY YTNATG---------AARAARGGNMGNGTNACNAARGAYAARAGYATHAARCCNATGAAR GAYAARGAYYTNTGYAAYGGNCCNTCNAARYTNTGYCARGCNYTNCAYATHACNAARACN AARTTYAAYCARATHGAYYTNACNACNTGYACNGAYATGTGGYTNGARAARGGNCCNTCN ATHGAYGCNGAYTGYATHGTNAGYTGYCCNMGNATHAAYATHGGNTAYGCNCAYGAYTGG ATHCARAARCCNYTNMGNTTYTAYATHYTNGGNAAYACNTGYGTNAGYGTNMGNGAYAAR AARGTNGAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARCARAARTTYACNYTNYTNYTNCARGARACNATGGCNGCN TTYAARCAYGARGCNGCNACNACNAAYAARCCNMGNYTNTCNYTNTCNGCNGCNGTNGGN GCNGGNAARGAYGTNATHGAYGCNGCNTAYGARATHGARAARATHTCNCARGCNYTNGAY TAYGTNATGYTNATGTCNTAYGAYTAYTTYGGNGCNTGGAAYCCNTAYACNGGNYTNGTN AGYCCNYTNTAYCCNCCNAARAAYGCNACN---GGNATHGAYAARATHTTYAAYGTNAAR TTYTCNGTNGAYTAYTGGGTNTCNAARGGNTGYCCNAARAAYAARYTNGTNATHGGNGTN ATHGCNTAYGGNMGNTCNTTYACNYTNAARAAYAARTCNGAYACNGGNYTNAARGCNCCN ACNAAYGGNGCNGGNACNACNGGNCARTAYACNMGNGARGCNGGNTTYYTNGCNTAYTAY GARGTNTGYAARATGATHAARMGNGGNGCNAARATHGTNCAYYTNGARCARGARAARGTN CCNTAYYTNGTNYTNGGNAAYCARTGGGTNACNTAYGARGAYCARGCNAGYYTNGCNGTN AARGCNGAYTAYATHAAYGCNGGNGGNTAYGCNGGNGCNGGNATHTGGACNTCNGCNYTN GAYGAYTTYAARGGNACNTTYTGYGGNCARGGNGAYTAYCCNGCNATGAARGTNTTYTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CCNMGNTGGMGNMGNAAYGTNAAYMGN YTNTGGCARGTNYTNYTNTAYGCNAARAARGTNTTYTAYACNATHGARACNTCNGTNCCN TCNAAYCCNGARGCNGCNGTNYTNTAYGAYCARGARCCNGARYTNTTYAARAAYMGNGTN YTNGARTCNGTNAARGCNGCNAARGARMGNYTNGAYCARCCNCCNTCNTTYGAYGAYCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CARCCNGARGCNMGNTTYCARGARGGNCAR CCNACNCARYTNCAYTTYTTYYTNCCNCARYTNGCNGAYACNTCNGGNGARATGGCNGGN GCNATHACNTCNMGNAGYTAYTAYCARGARCARMGNATHGAYYTNYTNTCNAARACNGAY AAYTCNCAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNGCNYTNGARACNGTNATGGAYGARYTNATH GAYGARGTNACNYTNGGNYTNTGYTTYGARATHCAYMGNTCNTGYAARATHGGNTTYTTY YTNYTNGAYGCNGGNGAYGARGCNTCNGARACNGARTAYGCNGTNATHGARMGNCCNGGN GTNGAYGTNYTNGGNCARATHCCNTCNAARAARAAYTTYGARTGYGTNTGYCCNAAYTGY CARMGNCAYYTNGCNGCNTCNMGNTTYGCNCCNCAYYTNGARAARTGYATGGGNATGGGN MGNAAYTCNTCNMGNATHGCNAGYMGNMGNATHGCNAAYAAYCARAARCAYGGNAGYGAY GARAGYGGNCARGAYGAYGARAAYGAYAAYGAYTGGAAYTAYGCNCCNGAYTCNAARMGN YTNMGNAARYTNAARAARGAYAARATGTCNGGNTCNCCNMGNAAYMGNMGNYTNGCNAAR YTNMGNACNAAYAAYYTNMGNAARYTNMGNAAYGGNGCNAAYCCNGGNCAYCARCARAAY GCNGCNACNACNAAYCCNYTNATHAAYCCNGTNGAYGCNGGNGTN------------GGN GAYYTNAAYCCNGGNACNYTNGAYACNCARGAYGTNACNTTYAGY---------TAYGAR AGYATGAGYYTNGARGARMGNAARGCNYTNYTNYTNACNAARTGYGGNGTNATHTCNGAY ATHACNAARAARATGTGYACNMGNTCNACNAARTGYGCNCARCAYTCNGAYGARCARMGN MGNCARGTNMGNCARYTNYTNYTNMGNCARGGNACNAGYAAYGARYTNGARGAYATHCAY GTNGAYATHGAYACNTAYGAYGAYGTNGARTCNCARTCNYTNMGNGARTCNYTNCARTGG GARGCNTCNTCNAAYTCNTCN---------------------AAYAAYAGYACNAGYAGY TCNYTNAARMGNGCNCCNACNAARGCN------------------TCNAGYAGYAARCCN AGYAARAGYAARAARTCNAARACNGGNAARGGNAGY------------------------ ------------------------------------------TGGATHTGYTCNTGYTTY TTYTCNAARAAYATHTAYGTNAARCARTAYAARYTNCAYGTNACNTTYATHGAYGARAAY CARTTYTAYCARGAYTTYMGNCARGTNYTNMGNATGAARGGNTGYTCNTCNGARAARCAR TAYCARGAYGTNYTNGARGGNGTNAARAARGARGTNGAYMGNMGNMGNACNTAYCAYTTY GAYGCNAAYGARMGNMGNCARYTNATHGCNTCNACNTAYAAYGTNYTNCAYCCNACNYTN TGGACNTTYCAYGARTCNTTYATHGAYGARMGNYTNATHACNATHGTNCARTCNYTN--- CARAARACNAGYAAYMGNCARGARGCNGARAARATHATHCARAAYAAYGGNGCNATHCAY GGNAAYTAYYTNTAYMGNGTNCCNGTNTTYAARCCNGAYTTYTGYGARAARYTNGTNGAR GARYTNCARAAYTTYGARCAYAGYTCNAGYCCNAARGARMGNCCNAAYACNATGTCNAGY TAYGGNGTNTCNYTNGAYGARATGGGNYTNTCNTCNGGNYTNYTNACNCCNGTNATGGAY AAYTAYATHCARCCNYTNACNGAYGCNYTNTTYTAYGARTGGTGYTGYGARAARYTNGAY TCNTTYMGNGCNTTYTCNGTNYTNTAYAGYAAYGAYAARGAYAARAARYTNAGYYTNCAY TAYGAYAAYGCNGARYTNACNYTNAAYATHTGYYTNACNACNCAYTTYGAYGGNGGNGAR YTNGARTTYMGNCARYTNTGGGGNGAR------------CCNTCNACNGARYTNGARAAY ACNATHGTNCARCAYAARATGGGNACNGGNATHYTNCAYATHGGNAARCAYATGCAYCAR GCNYTNCCNATHAARTCNGGNACNMGNTGYAAYYTNATHATGTGGATGMGNAGYTCNAAR ATHMGNAAYAARYTNTGYATGATGTGYGGNTCNMGNCCNGAYYTNMGNTCNGTNCCNATH GCNGGNGAYGGNTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TTYTCNATHGARAARACNTGGGAY AAYAARMGNTTYAGYCAYGAYCCNATHAARYTNACNTTYAGYGARGCNCCNTGYGGNAAY YTNAARYTNTCNGTNAAYGCNCCNTTYTTYAAYAGYCCNGCNAARCCNGAYGGNCCNGCN GGNCARCCNTTYCCNCARYTNTGGGAYTAYGARGTNGTNGARGCNTTYTTYYTNAAYGCN AAYGAYCARTAYYTNGARGTNGARYTNAGYCCNCAYGGNCARCAYYTNGTNYTNYTNYTN AAYGGNMGNMGNAARATGGTNAARCARYTNYTNCCNYTNACNTTYGCNGCNTCNATHGAY GGNGAYCAYTGGACNGGNGARGCNATHATHCCNACNGCNTAYYTNCCNTCNGCNGTNACN AARTTYAAYGCNTAYGCNATHCAYGGNGARGGNGAYAARMGNCARTAYGARGCNYTNTAY CCNGTN---------AAR---------GARGGNATGCARCCNGAYTTYCAYMGNYTNGAR CARTTYCARCCNYTNGAYATHGAYTCNGTNYTNAGYGGNTAYGAYTCNACNACNGTNTCN ACNATHTGGAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARGAY GARGAYGGNGGNAAYAAYGAYGAYGAYGAYGGNTAYCCNAGYGAYGGNATHGTNCARGTN GARGARGARGARGARGARAAYGAYACNGAYAAYGGNACNTAYACNATHGARGCNGAYGCN MGNCARMGNAARAAYATGMGNCARACNGCNAAYATGGGNATHGGNGCNMGNCCNAARACN TCNMGNGGNMGNCARACNTTYCCNCARCCNGCNTAYATHGAYCARACNAAYAARAARACN ACNAARAARAAYAARMGNAAYACNCARAGYAAYCARMGNGAYAAYAARATGMGNCARGAR AAYTAYMGNTCNGCNGARGARYTNATHCARGARAGYGARGTNAARGGNAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ACNCARGARGCNGTNTTYTCNATHGTNGGNAARCARATHATHGARAGYTGY GTNGCNGGNTAYAAYGGNACNATHTTYGCNTAYGGNCARACNGGNTCNGGNAARACNTTY ACNATGYTNGGNCCNTCNGARAAYGCNGAYAGYTTYCARCAYGARYTNMGNGGNGTNATH CCNMGNAGYTTYGARTAYYTNTTYAGYYTNATHGCNCAYCARCARGARYTNCAYGGNAAY AARMGNCARTTYYTNTGYMGNTGYTCNTTYYTNGARATHTAYCARGARCARATHTTYGAY YTNYTNGAYCCNACNTCNCARGGNYTNCAYYTNMGNGARAAYATHAAYAARGGNGTNTTY GTNGAYGGNYTNATHGARCARGTNACNTGYAGYCCNAGYGAYGCNTAYCARGTNYTNATH ATGGGNTGGYTNAAYMGNMGNGTNGCNGCNACNTCNATGAAYMGNGARAGYTCNMGNTCN CAYGCNGTNTTYACNGTNACNATHGARTCNAARGARGARGTNGAYGGNGTNCARAAYATH MGNACNTCNCARYTNAAYYTNGTNGAYYTNGCNGGNAGYGARMGNCARAARGAYACNAAY ACNGTNGGNACNMGNYTNAARGARGCNGGNAGYATHAAYAARTCNYTNTCNATGAGYAGY GAYTCNATHTGGYTNAARAAYTTYYTNGARGCNATGCAYTTYMGNGARGTNTCNGARAAY GARAARMGNGCNYTNCARGAYGTNGTNAAYCAYYTNCAYGARYTNTGYAAYAARAARGAY TCNTAYATHCARTCNGCNAARATGATHATHAARTTYMGNGARGARACNATHTCNACNYTN AARAARCARCAYCCNGGNCAYGARGARYTNGARMGNGARGARYTNGTNAARTCNYTNMGN TCNGARATHMGNGTNATHCARCARCARYTNGARTCNAAYCCNCARATGGCNAARYTNTCN GGNGARAAYMGNCAYYTNMGNAAYGARYTNAARCARYTNAARGCNCAYAGYTCNGTNGAR GGNATGYTNAGYGAYACNCARCAYATHGCNMGNYTNGARAARATHTTYMGNGARYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CCNGARGAYYTNAARGAYGAYMGNTAYTGGGCNMGNMGNGTNAARAAYAAYTTYGCN GCNAARMGNTCNMGNGAYGCNMGNMGNGTNAARGARAAYCARATHGCNYTNMGNGCNGCN TAYYTNGARAARGARAAYAARTGYYTNAARGAYGARATGACNAARYTNCARAARGARAAY ACNAARYTNAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYGTNGCNTAYYTNGAYTTYMGNYTN CCNYTNCCNYTNATHAAYATGGGNGGNCCNGGNCCNTAYACNGARGAYGTNTGGCCNGCN GARGARGGNTCNCARYTNTGYMGNGGNGCNYTNACNGCNTAYTAYACNYTNAARTTYTGG CARTTYATHCAYMGNGARCARTAYCARCCNATGAARGAYCAYAARGGNATGCCNATGTGY ATGTAYCARTTYMGNMGNGTNTTYAAYGGNTGYMGNATHCCNGGNGTNTTYCARGAYAAR YTNGTNAGYCAYTTYAARACNGARTCNGARGGNGARTGYCCNTCNCAYATHATHGTNTCN TGYAARGGNCAYYTNTTYYTNATGAAYGTNYTNGAYGARGCNGGNGARATHATHACNCCN ATGGARYTNGARATGCARTTYATHMGNGTNMGNGAYGARGCNGARMGNYTNGGNGCNGCN CARGGNGTNAAYTAYYTNACNAGYATGCCNMGNACNGCNTGGGCNCARTAYMGNAAYCAR YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GCN GCNMGNGGNATHTAYATHCCNGGNCARAAYCCNTAYGCNCARYTNCCNCCNGCNCCNCCN ACNCARTCNGTNYTNCCNAAYGGNATGACNGCNMGNTTYGTNCAYGCNCCNCARCAYTTY GCNGTNGTNTCNACNCCNGGNGGNCAYCCNCAYCAYYTNGCNGCNGCNCARTAYGCNACN TCNATGCCNTAYCCNGGNGTNGCNGCNATHCCNACNTCNACNGCNGCNTAYYTNCCNACN CAYCARTAYCCNGGNGGNATGGGNTTYCARGGNGCNGCNYTNGCNGGNMGNTCNATGCCN CCNACNCARTAYGCNATHCCNACNCCNYTNCARGCNGGNGCNCCNYTN---TTYGCNGCN GGNTAYTCNCAYCCNGTNCARGCNGGNATHCARGCNGGNGCNMGNCAYYTNCARATGGGN CCNATGGCNGGNYTNCCNCCNGGNTAY--------------------------------- ------------------GTNGTNATHACNTGYGGNGGNACNATHGAYAARCAYTAYCCN CARGGNCCNGGNGCNTAYGCNTTYGARTTYGGNGAYGCNGCNGTNGAYAARATHYTNCAR MGNGTNAGYTCNACNMGNACNTAYACNATHGARACNATHTGYGCNAARGAYAGYCARGAY ATGACNGARGAYGAYMGNAARTCNATHYTNAGYTCNGTNACNGARAARAARCARTCNYTN TTYYTNATHACNCAYGGNACNGAYACNYTNTGYGCNACNGCNCARTAYYTNATHCARGCN GGNGTNGGNCARGGNGAYCARTTY------CAYAAYGGNGARAARACNGTNGTNYTNACN GGNGCNTTYAARCCNGARACNATGAARGAYTCNGAYGCNGAYTTYAAYGTNGGNTTYGCN YTNGGNGTNYTNCAR---TAYTCNCCNCCNGGNGTNTTYATHGCNATGGARGGNGTNYTN ATHGAYGGNGCNCAYGCNACNMGNAGYAARCARGGNAARTTYATGGAYGCNMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATGATHCCNGGNCARTTYAARAARGAYTCNMGNGTNTGG YTNCAYAARAAYTCNAARCAYCCNGARACNGARYTNTCNMGNGARTAYMGNAAYGAYTGY TAYMGNCAYGARACNMGNATHTGYCCNGCNTAYGARGAYGARGGNTGGGAYMGNACNCCN AAYATHACNGGNGCNGAYGGNAARCCNTAYAARAARGAYAGYMGNACNTGGYTNCAYAAR TGYTCNACNAARATGYTNTCNMGNTCNGGNMGNGCNGARACNMGNAGYMGNGCNAARGAR GAYATHAARMGNGTNATHAAYGCNATHGAYAARGTNMGNAARTGGGARAARAARTGGGTN ACNYTNGGNGAYACNTCNGTNACNATHYTNAARTGGGTNCCNGTNACNGCNCARGARAAY CCNGGNGCNYTNMGNAARATHCCNGGNGTNAARACNAARACNTAYTCNAARGCNMGNGTN GARMGNGARMGNGARYTNTAYAAYGCNGARACNAAYGGNACNCCNMGNGCNAGYTCNCCN GCNGAYTCNCCN------CCNACNAAYYTNTCNAAYACNAGYTCNCCNTCNTCNAARGCN GCNACNTCN------GAYAARGCNMGNAAYGGNGTNGTNAARAAYTCNCARGGNTCNGTN GTNTAYACNGARGARAAYACNCARCARTCNGTNGGNTCNTTYGGNTCNGARAAYYTNAAY GARGAYTCNAAYATGTCNTTYCCNGARAAYAGYGARYTNAGYGARCAYGCNGARAAY--- GARTTYTCNCAYGAYAGYAAYGAYGGNGAYCCNGGNATGMGNGTNGCNATGAGYATGATH GGNGAYGARGAR------------------------------------------------ ------------------------------------------------------------ ATGTCNGARAARCAYAGYTTYGGNATHGCNCCNGTNACNTGYCAYGCNTTYAAYAARGAR MGNAAYGGNYTNGCNATGTCNYTNAAYGAYTCNGAYGTNAARGTNTAYAARAARTCNGGN GCNMGNTGGGARGARACNGAYACNYTNATHGARCAYGGNCARMGNGTNACNAGYATHGAY TGGGCNCCNAAYAGYAAYMGNATHGTNACNTGYTCNGCNGAYMGNAAYGCNTTYGTNTGG ATGYTNCARGARGGNAARTGGAARCARGTNYTNGTNATHCCNMGNATHAAYMGNGCNGCN ACNTGYGTNAARTGGTCNCCNAARGARAAYAARTTYGCNGTNGGNAGYGGNTCNMGNYTN ATHGCNATHTGYTAYTAYGAYGTNGARAAYAAYTGGTGGGTNAGYMGNCAYATHAARAAR CCNATHMGNTCNACNGTNACNTGYYTNGAYTGGCAYCCNAAYAAYGTNYTNYTNGCNGCN GGNTCNACNGAYTTYAARTGYMGNGTNTTYTCNGCNTAYCARAARGARGTNGAYGARMGN CCNGGNTCNTGYTCNTGGGGNTCNAARATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GAYATGTTYACNAARTTYTCNACNACNTTYACNTTYATHACNCCNAAYGTN ATHTCNTTYGCNCAYYTNTTYYTNGCNYTNGTNTCNGGNAARTTYGTNGCNTCNGARAAY YTNCAYGAYMGNMGNATHGGNGTNGTNYTNTTYCARTTYMGNACNTGGYTNGAYGCNTTY GAYGGNGTNGTNTAYMGNTCNCARTCNAAYACNCAYYTNCARTTYCARTCNGTNMGNTCN ACNYTNGGNTAYTAYGTNGAYACNAAYTGYGAYGTNYTNGGNGGNGTNTTYYTNTGYTTY GGNGTNYTNTTYTAYYTNTGGAARMGNTTYGAYCCNCAYAARCARGAR------YTNCCN TCNTGGAAYAARGGNCARGARGCNGCNYTNGTNGGNAAYGGNATHCAYCAYGGNGCNACN GGN------MGNGARACNCAYAGYAARAARTAYGTNTTYTGGNNNGTNYTNTGBTAYGGN YTNTGYYTNGCNTTYGCNGGNAARTCNTGGGAYYTNATGGTNGGNGAYTTYMGNCARGTN TTYCARGARGAYYTNAARGAYCCNCARAARTCNYTNYTNCARTTYCARATGTGYCAYTCN ACNATHGCNATHTTYYTNYTNCARATGTGGMGNATHYTNGARGGNCARGCNYTNYTNCAR TAYYTNYTNATHCCNGTNTTYYTNGAYAARGTNTGGGARTTYYTNAAYTAYACNCARTAY ATHYTNYTNAGYATHYTNGTNGGNYTNTAYGTN--------------------------- ------------------CCNAARYTNATHGTNTTYGAYYTNGAYTAYACNYTNTGGCCN TTYTGGGTNGAYACNCAYGTNGAYCCNCCNTTYAARYTNGGNAARGAYAAYAARATHTAY GAYAGYMGNAARCAYCARGTNAARCAYTAYCCNGAYGTNCCNCARATHYTNTCNAAYYTN CAYGCNCARGGNATHAARYTNGGNATHGCNTCNMGNACNGGNGCNATHGAYGAYGCNAAY GAYYTNGTNMGNYTNTTYGAYTGGGAYAARTAYTTYCAYTAYMGNCARATHTAYCCNGGN TGYAARGTNACNCAYTTYAARAARYTNCARAARYTNAGYGGNYTNCCNTTYGARGARATG YTNTTYTTYGAYGAYGARCAYMGNAAYATHTCNGAYGTNTCNGCNYTNGGNGTNACNTGY ATGTTYGTNGARGAY---GGNGTNTCNCARAGYTGYTTYACNAARGGNATHGARYTNTTY CAYAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARACNAAYCAYTGGGARGTNGAYCCNATGAARGAYMGNGTNCARTAYATH YTNAAYAARCCNGAYACNAAYTGYGGNAGYTAYMGNAGYCARACNAGYYTNGAYCAYAAR CCNAARAAYAARYTNTCNYTNCARGAYGCNTTYGTNYTNAARMGNCARAAYTTYATHTCN AARTCNTCNGARMGNCARAARMGNYTNMGNYTNTCNACNGARAAYMGNCARYTNCARGAR TGYTTYMGNYTNGARMGNGARGCNATHTTYGCNGARCARGAYMGNYTNCCNGCNCCNAAY YTNTAYGCNCAYCCNTAYAGYGAYAAYYTNTAYCARCCNAARCAYMGNATHTTYACNAAR AARGARATGAARGAYATHACNTCNAARAARTAYCARMGNYTNCCNGARGTNGTNGGNAAR AARGARGARGAYAARAARAARATHGARGCNGARYTNAAYMGNYTNMGNGCNAGYYTNTTY ACNAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TGGGTNCAYTGYAAYGGNTGYTAYTGYCARCCNGARACNGGNGTNGTNMGNTTYTTYATH ACNAAYTGYAGYCAYATHTAYTGYGARAARTGYGTNAAYGARTGYACNAARGARMGNTGY AARGTNTGYCARTCNCARTGYACNACNYTNGARYTNGGNGCNAARYTNCARAARGARGTN GARAGYYTNTTYGARGARCCNTCNACNATGGTNCARAARTGYYTNAARAARATHAAYCAR ACNATHGARTTYCARAARAGYCAYCARMGNMGNTGGTGYMGNCAYYTNAARGARGTNYTN MGNCARCARACNAGYCARYTNAARGAYGTNAARAARYTNGTNACNCARTAYMGNAGYYTN GARAARGARGTNATGGAYYTNAARAARGARAAYAGYTAYYTNAARTGYYTNYTNGCNAAR AAYGAYCCNGGNYTNMGNGCNGCNTCNMGNGCNGGNYTNGARATGACNACNAARTCNTGY ACNCCNYTNTCNGTNCCNMGNCCNATHTAYYTNTCNAAYTCNGAR---ATGATHGTNTAY AARTGYATHATHACNGGNGAYGARTTYTTYAAYGAYAGYTTYGAYTTYAARGAYGARGGN GGNTTYTAYGTNYTNAARGGNAARTTYGTNACNAARAAR---ACNGAYGAYATHGAYGAY TCNGCNYTNGGNGGNAAYCCNAGYGCNGARGARGCNTCNGAR---GGNACNGARGGNGGN ACNGARTCNGGNATHGAYATHGTNATGGCNAGYMGNYTNGTNGARACNGGNTTYGGNACN AARAARGARTAYCARGTNTAYATGAARGAYTAYACNAARYTNYTNTTYAARGCNYTNGAR GGNACNAARTCNGCNGARGARYTNGTNGARATHAARGCNGGNTAYCARGARGCNTAYAAR GCNGCNTGYGGNMGNTTYAARGARTAYCARTTYTTYGTNGGNGARACNATGAGYCCNGAR GGNYTNACNGCNYTNATHGAYTGGAARGAYGARGTNGTNGAYGGNAGYACNGTNAAYGTN CCNTAYTTYTAYGTNTAYAARGCNGGNGTNGTNGCNGAYAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ACNTAYMGNAAR TTYTAYGGNMGNMGNCCNGAYGGNYTNAAYGGNGCNATG--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGAARGTNAGYGGNAARCCNATH GCNAARAARCARAGYYTNGGNAGYCARAGYCCNYTNGTNGAYTCNATGTCNGAYGTNMGN ATHGARGAYGGNMGNYTNTGGTAYGAYAARAARTGGTTYCARMGNAAYAGYATGGTNCAR ATHGAYAAYAARGARACNGGNTCNMGNATHCAYGGNACNATHACNAAYATHATGAAYAAY CARATHTCNATHAARAARAGYGGNGAYAGYTCNAARYTNMGNATHTGYGTNTCNCAYATH CARMGNGGNAARTAYACNATGAARAARMGNGCNACN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTCNMGNGCNGGNGCNTCNAARGCN MGNGGNGCNGAYAARACNAARCCNCCNGCNTCNCARACNCCNGTNATHGCNCAYGARATH GTNCCNGGNAARTTYAAYGAYAAYGAYTGGAAYTTYATGYTNGARMGNGAYGGNGGNGAR GARTTYGTNYTNGAYATHGTNGAYGARYTNATGGARAARACNATGGAYACNATHTAYGAY AAYTAYATHGARMGNCARYTNYTNCCNTTYACNATHACNCARGCNMGNGAYGCNATHATH GARATHATHGARTGGCARTTYYTNGCNMGNGAYGARGGNGARGAYAAYATHACNACNGAY YTNGGNTGGATGCARGAYGARGARCCNGARCCNGCNGARACNGAYTGYTGGGCNCARGGN TCNGTNCCNMGNAGYATHYTNYTNGCNCCNACNCCNGARYTNGARGARATHCCNGARGAR CCNGARGARATHCCNYTNGARGCNGARGAYYTNGCNACNACNGARGARACNGTNCCN--- ------------CARGARCCNGARGARYTNGARGAYGTNGTNTCNGARCCNGAYGARACN CCNGARATHGTNGCNTCNGCNGARGARATHGARATHAARGTNCCNTCNCCNCCNACNATH TGYACNTCNAARTCNAARATGTCNAARACNAARTTYMGNCCNTAYMGNGGNAARYTNAAR TCNGCNGGNGTNAGYAARATGACNGARTCNYTNGARGARACNGARATGAARATHATHTAY AAYGARATHGTNGCNTCNYTNCCNCCNAAYGARGARAARCCNAGYACNYTNYTNAAYATG CCNGCNTCNTGYACNAGYATHYTNAARGTNCARACNGGNMGNCCNCCNGGNAAYAARGAY GTNATHTAYGAYGARATGGGNAAYGTNGTNGCNGTNATGAARYTNGAYCCNGARAARYTN CCNACNCAYAARGTNAAYGTNAARTAYCAYGTNGTNGAYCCNGCNGTNGARGCNGCNCAR GCNMGNYTNGAYGCNATGMGNAARGGNAARTCNACNGGNAGYMGNATHMGNAARATHAAR ACNACNAARAGYATHTCNGTNGCNACNGCNGGNGGNACNGCNAARAGYAARGCNACNATH ACNGGNGCNTCNGTNGCNCCNYTNCCNCCNCCNYTNGTNGARGAYMGNGAYAGYATHYTN AARGGNGARTCN---ATHGTNMGNATGCCNMGNATHGARGARATGGARGCNGCNAAYGGN GTNATHATHMGNGGNGGNGGNMGNGTNAARAARGGNCCNGGNMGNTAYTAYGGNAARYTN GAYATHYTNGARGAYCAYCARAARGGNATGAARCCNGTNACNGTNMGNYTNACNAAYAAY GGNATHACNGTNAAYGAYYTNYTNGAYMGNAAYACNCCNATHYTNMGNCCNYTNACNGAY ACNGCNCCNYTNCCNCCNATHATHTCNGCNMGNCAYTCNCCNCCNTCN---CARGTNTCN ---------------------GGNGCNGGNGTNGTNGGNYTNAGYTCNGCNATHAAYGTN YTNGCNTCNATHCCNAAYGCNACNGTNACNGTNATHGCNGAYYTNTTYGGNCCNCARACN GTNAGYTAYGGNGCNGGNGGNYTNTAYMGNCCNGAYATGGARAARYTNGTNGAYAAYTCN AAYTAYGAYACNATGGTNCARTGYYTNMGNGAYTCNTGGAAYCAYTTYTCNAGYYTNGCN ATGTCNGARGARGCNCARCAYAGYGGNCARATGYTNGTNCCNGGNATHYTNGGNCAYMGN AARAAYATGGAYAARGGNTAYACNYTNATGAARGAYACNGCNTTYAAYTTYMGNCARYTN ACNGARAARGARACNAARMGNATGGGNTAYCCNGARGARTTYAARTAYGTNTAYACNTGY GTNACNGTNGTNTCNCARGGNAGYGTNTAYATGGAYTGGYTNCARACNAARTTYGTNTCN AARGGNGGNAARATHGARMGNMGNACNGTNGGNAAYTTYGCNGARYTNTAYGGNAARTAY GAYGTNGTNATHAAYTGYTGYGGNYTNMGNGCNAARACNTTYYTNTCNGAYAARGARTGY TTYCCNACNMGNGGNCARYTNGCNATGYTNAARGCNCCNTGGTTYAARTAYTTYAAYTAY YTNGAYACNGAYGTNTAYGTNATHCCNCAYATGGAYAARGTNATHGTNGGNGGNATHMGN ATHAAYGAYGAYCCNGAYACNTCNGTNAARCCNGARGTNACNAARTCNATHYTNCARAAR GCNGARGCNATHTTYCCNCARYTNAARGGNGCNGARYTNATHGGNGARTGGGCNAAYTCN MGNCCNGGNMGNACNTCNATHMGNYTNGARACNGARATGGTNAARACNGGNGAYAAYCAR TTYYTNCCNGTNGTNCAYAAYTAYGGNCAYGGNGGNAAYGGNATHACNYTNAGYTGGGGN ACNGCNGTNCAYGCNGCNYTNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ACNGAYTCNATHCARGAYYTNGARGCNGCNGAYMGNGCNATHCARTTYAARYTN GGNTGGTTYGGNAAYCCNATHTAYGGNGGNACNGGNGAYTAYCCNCARGTNATGAARGAY TCNGTNGCNAARAARAGYAARGAYCARGGNYTNYTNAARTCNMGNYTNCCNGCNTTYACN GARGARGARAARAARYTNAAYCARGGNGCNTAYGAYTTYYTNGGNATHAAYCAYTAYACN ACNAAYYTNGTNGCNGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGGMGNGTN GCNAAYTTYATHATGTGYGCNTTYTTYTTYYTNGCNGCNTTYGCNAAYATGAAYGAYGGN GAYTGGTAYTTYTGGGCNCCNATHTAYYTNTGYCCNGGNYTNYTNTCNYTNAARGCNGCN YTNCARCCNYTNTCNATHGGNCAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TGYTCNATHTGYTCNAARYTNYTNAGYGAYMGNAARGCNYTNAGYAAYCAYATHGCNYTN CAYCCNMGNGARAARAAYTAYGARTGYACNGCNTGYTCNAARAARTAYTTYTGGTTYGAR TCNYTNAARAARCAYGARAARATHCAYGCNAARGGNAARTTYTAYAAYTGYAAYATGTGY GARMGNTCNTTYATHTCNAAYTTYATGYTNCARYTNCAYAARAAYGTNAARCAYAARAGY YTNGTNTTYAAYTGYACNATHTGYAGYAARTCNGTNTAYAGYTCNGCNACNYTNAARMGN CAYYTNAARAGYCAYGGNTTYATHAARCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AAYTTYCARMGNATHAARMGN CCNACNGCNGAR---GAYAGYGAYGAYGAYTTYGGNAARGGNAGYGGNATHAARGTNGAY MGNGARCARYTNGARAARYTNAARGAYATGTTYCCNAAYGCNGAYNNNAARAARYTNAAR GCNGCNYTNTTYGCNTAYGGNAARAAYTTYCARMGNGCNGTNGARTAYGTNMGNAAYGCN GARMGNGCNAARMGNCCNGCNCCNGARGARGGNTAYGAYGARYTNCCNGTNATHACNGCN AGYMGNAARMGNATHAARATGATGCCNCARACNCCNTCNCCNACNAGYGARAARGARTTY ACNYTNACNACNTCNGARCCNAAYGAYGGNAGYACNATGGAYTTYYTNAARACNTGYTTY CCNAGYAARTCNGARGARGCNATHAARACNGCNYTNAARGAYAGYGGNGGNGAYGTNGAR AARGCNTCNATHATGYTNACNYTNAAYAAYAARACNATHGTNAAR------TCNACNTCN GAYAAYTCNAARYTNATGAARGCNGTNAGYGAYCARAARGCNAARGCNAAYAAYAGYAAR AAY------------CARCARMGNGAYGAYGCNAGYGAYGAYGAYGAYGCNGARTAYAGY GAYGAYTAYGAYAGYGGNGAYAGYGAYGAYAGYGARAAYTTYGAYAAYAARACNYTNAGY GARATHGARYTNCAYYTNCARTTYTTYAAYGARGCNACNYTNGARGARYTNGCNGCNATG CCNGGNTGYTCNAARAARAARGCNGARACNATHATHAAYCARMGNMGNTTYGARTCNTGG GAYGAYYTNTGYYTNAARTTYGAYACNAAR---------------CCNYTNYTNTCNGGN TGYAARGARATHATGMGNGTNMGNAAYATHATHCAYMGNYTNATGGTNMGNTGYGARAGY ATGTCNCARAARATGGARACNGTNGTNTCNACNYTNACN---GGNCARAARAGYCARGAY ATGAGYGARTCNGGNAGYATHGGNMGNCARCCNGARYTNYTNAAYAAYGARTTYTCNYTN AARCAYTAYCARYTNATHGGNYTNAGYTGGYTNMGNYTNATGCAYGARCARGARYTNAAY GGNATHYTNGCNGAYGARATGGGNYTNGGNAARACNATHCARGCNATHTCNTTYATHGCN CAYYTNYTNGARGARGGNGARGGNGGNCCNCAYGTNATHATHGTNCCNTCNTCNACNATH GARAAYTGGYTNMGNGARATHCARYTNTGGTGYCCNGCNATHAARATHATHGTNTAYTAY GGNTCNCARGARGARMGNMGNGCNGTNMGNCAYTCNATHTTYGTNGAYGARGARGAYTTY AAYGTNYTNYTNACNACNTAYAAYATGGCNACNGGN---------GAYMGNGTNTTYTTY AARAARTAYCARTTYCAYTAYGCNATHTTYGAYGARGGNCAYATGYTNAARAAYATGTCN TCNYTNMGNTTYCARAAYYTNATGAARATHGTNGCNGARMGNMGNYTNYTNYTNACNGGN ACNCCNYTNCARAAYAAYYTNYTNGARYTNATGTCNYTNYTNTGYTTYGTNATGCCNGAR ATHTTYCARGGNAARACNGAYTCNYTNAARAARATGTTYACNATGATHTCNAARTCNGAR GAYAAYAARAARAGYMGNTTYGARTCNGARMGNATHGCNCARGCNAARMGNATHATGAAR CCNTTYGTNYTNMGNMGNYTNAARAARGAYGTNYTNTCNCARYTNCCNAARAARACNGAR AARYTNATHAARTGYTCNYTNACNGARTCNCARMGNCARYTNTAYGAYGGNATGGTNTCN MGNTAYGCNCARGARGTNGARGAYMGNAARGAYGGNGAYACNTCNGGNGGNGTNGGNGTN TTYATGCARTTYMGNAARGTNGCNAAYCAYCCNYTNYTNGTNMGNAAYYTNTTYACNGAY GAYGTNYTNGARAARATGGCNAARAARYTNTCNACNGARCCNTCNCAYMGNGARMGNGGN GCNATHCCNAARYTNATHCARGARGAYATGTCNGTNATGAAYGAYTAYGARYTNATHTCN YTNTGYAARCARTAYAARAARTAYYTNGGNMGNTTYATGCCNGAYCCNGAYGTNATGTAY CARTCNGGNAARATGGARAARYTNGAYGARYTNYTNCCNGARATGAARGARMGNGGNGAY MGNGTNYTNYTNTTYAGYCARTTYACNATGATGYTNGAYGTNTTYGARCARTAYYTNGAR AARMGNAARCAYAARTTYATHMGNYTNGAYGGNCARACNCCNGTNCCNGAYMGNYTNCAR YTNATHGAYMGNTTYACNAAYGARCCNGAYATHTTYATHTTYYTNYTNTCNACNMGNGCN GGNGGNYTNGGNATHAAYYTNGTNGCNGCNAAYACNATHATHYTNCAYGAYATHGAYTTY AAYCCNTAYAAYGAYAARCARGCNGARGAYMGNTGYCAYMGNYTNGGNCARAARMGNGAR GTNTCNGTNATHAARYTNATHGGNGARGAYACNGTNGAYGARTCNATGYTNMGNTGYGCN AAYAGYAARYTNAARYTNGARAARGAYATHACNGGNGCNGAYCARGAYGARGAYGARAAR AAYAARAARGAYGTNGCNAAYYTNYTNAARGARGTNYTNAARCARMGNCARAARCARAAR GCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGGCNGAYTCNAARTCN AGYYTNGCNMGNGAYGGNACNATGCARGTNACNGCNAARGARGGNATHGAYTAYYTNAAR TCNTCNAAYAARGAYACNYTNYTNAARGCNCARGGNYTNGTNAARGAYAARCCNGCNGTN CARMGNGAYGGNACNATGGTNTCNACNGCNAARGARGCNGAYMGNYTNYTNGAYGGNAAY AARCCNGAYGCNGAYGCNCARACNMGNGGNCARCARAARCARATHGARGARYTNAARAAY GARAARGTNGARCCNAARGCNAARAARGCNAARYTNGCNAARGAYGGNACNATGGCNGTN ACNGCNAARGARGCNAARGCNYTNYTNGCNGGNGARAARYTNGGNGAYACNMGNCARGAY ACNTCN------AARAGYAARTCNAARACNCCNYTNMGNAARAGYAAYACNATGGCNAAR ACNGTNGARGARGCNAARGGNGTNYTNGAYGGNGCNGTNGAYGTNAAYGARGGNMGNAAR ACNMGNTCNCARAGYMGNGGNGAYGCNCCNAARCCNTCNATHAARAARCARGGNACNATG CARCARACNGCNAARGAYGGNAARGCNTTYYTNAARMGNACNAARGGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGCCNAGYYTNCCN ATH---GTNAARCAYACNGTNACNGCNATGGGNGCNAAYACNGCNMGNGCNGCNTCNATH YTN------------CAYATHGTNAARCCNCAYATHCCNYTNATHCARTTYCCNMGNMGN ACNCCNGGNGTN------------YTNTCNGCNGAYATHAGYAAYCCNAAYACNGTNGAR TCNYTNGTNTCNCARGCNGTN---------GCNTCNAARTCNAARCCNAAYGCNGTNAAR TCNAARGGNTCNCCNGTNGAYTCNAGYGARYTNCCNYTNMGNTTYMGNMGNAARCCNATH TCNAGYGARGARATGGARTTYATHGARAARGGNGGNCARGTNATHATGAARATHGTNYTN GCNYTNGTNYTNATHTTYGCNACNGTNAAYTGYCARCARAARMGNCARATHGGNATHTGY GTNGARGARTGYAGYYTNACNMGNAGYCCNYTNYTNAARTCNCARTGYCCNGAYGGNCAR ATHTGYAARTCNAAYGGNTGYGGNCAYACNTGYCAR---------------CCNGCNTTY GAYGCNACNAARTGYCCNGGNGTNATGTGYGCNATGTAYTGYGARAAYGGNTTYGARACN GGNAARGAYGGNTGYCCNGTNTGYMGNTGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARAARACNGAYCCNGCN ATHGCNGCNGCNMGNACNCARAARMGNYTNAARMGNATHGAYAARGARATHAARMGNYTN TCNMGNTTYGGNAARATHYTNAARCCNGTNGAYGARATHGARGTNGAYMGNMGNAARYTN ATGGGNTCNGGNGARMGNAARMGNGAYGTNGCNGTNYTNACNTTYGARGARTCNGARGGN MGNGCNYTNYTNCAYAARAARTGGCAYTCNTAYMGNAAYAAYMGNTAYAGYGARATGYTN TCNACNTTYGCNAARGTNGARGAYGCNCARGARGARGCNYTNGARGARYTNMGNGCNGAR TCNGARGCNYTNTAYYTNGCNGCNATHCARAARAAYGAYGAYTTYYTNCCNYTNGTNTTY GAYGGNCCNACNGARACNCCNCCNATHAARGGNTAYGCNGCNCCNGAYGGNGARTAYGTN GAYACNACNMGNAARTTYATGGGNYTNAGYTGYGARYTNGAYTGGAAYATHGAYATGGAR GTNAAYYTNTTYCAYGCNATGMGNGGNCAYAARCCNGCNGGNGTNAAYMGNCAYTTYCAR ATGATHGCNATHCAYGAYAARYTNAGYTCNTCNTCNAARAARATHACNTCNGGNGAYGTN TGGAARCAYYTNYTNACNYTNTAYGAYYTNCARGCNYTNAAYGARTCNGARATHGTNCCN TTYCCNAAYAARAAYGGNGAYTTYTCNTTYCCNGARAARGARATGGTNGARYTNAGYTCN AARTCNTTYCCNMGNTCNTCNCAYATHAAYACNGTNACNGCNGAYTCNACNAARACNGAR GCNTTYGGNAARAAYATHTCNAARYTNAAYACNAARYTNGARACNAARCCNGCNTGYCAR ACNCCNAARYTNGARTCNAARYTNGAYCCNAARTCNGAYAGYMGNTCN------------ ------------AGYACNCCNAAYMGNATHGARCCNAARTCNTCNCAY------------ ------------TCNAAYAGYAGYTCNAARTCNCAYCARACNACNCCNTCNTCNGTNCCN TCNCCNTCNCCNAARMGNACNAARMGNACNMGNAAYGTNAAYTCNGCNACNGCNAGYCCN GCNACNCCNACNGARCCNCARGTNAARMGNMGNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGGATHYTN GCNTAYACNYTNAARTCNAGYGTNAARGAYYTNGTNYTNYTNYTNYTNTTYYTNTGYGTN GGNACNYTNATHTTYTCNACNYTNGTNTAYTTYGCNGARMGNTAYCAYCARCCNAGYTTY TCNAGYATHCCNAARTGYTTYTGGTGGAGYGTNATHACNATGACNACNGTNGGNTAYGGN GAYATGGCNCCNCARACNMGNTGGGGNTAYYTNATHGGNACN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CAYYTNAAY GAYCARATHMGNCARYTNAARGAYGARAAYGGNMGNYTNTAYAARYTNYTNAAYGARAAR GAYTTYGARATHMGNCAYTTYAARAARAARAARGAYGARAARACNGCNAAYGCNATHGAY ATHAAYGTNACNAAYGARACNGCNTCNACNAARATHGTNGARYTNAGYAARAARGTNMGN GARYTNACNGCNGARAARGARTCNGARAARACNMGNTGYMGNCARTTYCARAARAARTGY CAYGAYYTNCARYTNCARYTNCARTCNCARAAYTCNGCNTCNGAYAAYCARTCNGTNACN GGNTCNATGGTNAGYYTNMGNTCNGCNGTNTCNACNAARGARGAYGAYGGNGTNGAYGTN AARGCNYTNCARGAYMGNYTNAARCARTCNGARTCNMGNYTNACNGAYTTYMGNAAYCAR TGYCARCARYTNMGNCARGARYTNAARGTNGCNAAYAARGTNYTNTCNCARGARATHGGN GARAAYGTNAAYATHCARTCNYTNYTNAAYGARACNAGYCARTGGMGNGGNMGNGCNCAR CARATHATHGCNYTNAAYCARAARGTNGARGARYTNAARGTNMGNTAYGARGGNATHCCN CCNCCNGGNGARACNACNGGNATGGARAARGTNTCNACNGCNMGNMGNMGNCARGARGAR AARTAYMGNGARGARYTNMGNAARGCNGARAARGARMGNAARGARGCNCARGARACNAAY ATHAAYMGNYTNAARAARYTNGARGARGAYTAYTCNCARGTNAARAAYAARYTNGAYGCN TCNAARACNMGNAAYAARGTNYTNTCNAAYGARATGAARGGNCAYAARGCNCARGTNCAR ACNYTNYTNAARAARAGYCAYAAYGAYGAYGARTTYATHGARGCNYTNATGMGNCARCAR AARCARYTNAARGARATGATGGARACNACNACNTCNAARCARTCNGCNGCNCAYCARGAR CARCARCARCAYYTNYTNGCNATGAAYATGAARTTYCARCARGAYAAYAAYGTNGTNGAR CARYTNAARATGATHGCNGCNCARAARGARTCNCARGTNAARYTNYTNGARATGGARYTN GARCARYTNMGNAAYTCNCAYAAYAARCCNCARGCNTGGTCNGARAAYAAYTCNACNTCN CCNTCNCARACNACNGARGCNTCNGCNACNCCNYTNCCNCCNACNGGNAGYAAYAAYAAY AGYGGNACNTTYATHMGNYTNMGNGAR------AAYAGYCARYTNTCNAGYGCNMGNTCN AAYAGYMGNTCNATGTCNMGNYTNTCNGGNCAR---GCNACNCCNACNCARCARMGNGGN ACNACNCCNACNAAYGGNGTNAARTCNCARGARATGGARYTNMGNTAYCARATHCARGAR YTNACNGTNATGTCNMGNGCNATHGARGTNGARAARGAYAARATGACNGARYTNGTNCAR GTNYTNCARAAYMGNYTNTCNGARGARGTNGARMGNCAYAAYAARACNCARCARGARYTN CARACNCARAARMGNACNGGNATHGARYTNGARAARYTNYTNGGNMGNAARAAYATGGAR GCNATGMGNGGNGGNGAYACNAARTGYYTNGAYTCNATHMGNGGNGAYGAYGAYGARGAR GAYGAYGARAAYTGYAARTCNACNAARAARGARYTNATGACNMGNYTNCARATHCARAAR GAYGARATGCAYTCNYTNAARYTNTCNYTNCARMGNAGYATGAARGCNAARGARGAYGAY YTNAARGTNTAYAGYAARACNYTNGAYGARACNAARCARGTNTTYYTNYTNGCNYTNMGN CARATGAARGAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARGCN MGNGAYCARMGNGARCARGARGCNYTNAARGARCARCARATGGCNACNYTNAAYAARGTN YTNGCNACNACNYTNGAYYTNACNGAYGARGCNAARCARMGNATHATHCARGARCAYGAR CARAAYATGCARAGYYTNTCNAAYAARYTNGTNMGNAGYAARYTNMGNCARCARAARAGY YTNGARATHAARYTNAGYCARMGNAARGCNAARYTNGCNGARYTNAARCARAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNGAYGCNGGNGARTAYAARGTNGGNTGYGTNGCNGARGGNAGYAAYCCNAAR GCN---GAYGTNAGYYTNGAYTTYCAYGGNGTNGCNATH---GARGGNAGYACNGTNGAY GCNAARYTNATGGARCAYGARTTYMGNMGNTAYMGNACNGCNTCNTCNGCNAAYYTNAAY YTNATGGTNAGYAAYTCNGGNCARGARYTNAGYTGY------CARGGNACNGAYGCNACN GGNACNTCNYTNACNGTNAARACNGCNATHGARGTNAAYATHTAYGARGCNACNATHATG TGYAAYGAYACNGAYGCNTAYATHGGNCARAARAAYCCNATHGTNTCNTGYGTNGTNAAY CAYACNGAYYTNCARGTNACNGGNTTYGCNTTYCARGTNGGNGAYACNGGNGARATHATH AARGARGGNCARAARAAY---------GGNCARAAYATGTTYGTNAAYGTNACNAAYGTN GARGARGGNATHAGYATHGTNTCNYTNGAYYTNCAYAARGCNAARCAYGARTAYYTNAAY AARAAYTAYTAYGTNYTNATHGAYATHAARGGNGGNCAYACNAGYAARGARAGYGTNMGN YTNAAYAARATHCARGGNAAYGAYGGNYTNGAYGARAAYGARAAYCCNGGNGGNAAYGGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AARTTY CAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNTGGGAYGTNATGTTYGAYTTYAAYYTN TTY---TGGAAYGGNACNYTNTGGGAYCCNAGYAAYGCNGARACNTTYYTNAARTAYTCN GCNGAYMGNMGNTAYCCNYTNCAYGCNTTYCARYTNGGNAAYGARCCNAAYTCNTTYCAY TAYAAYTTYAAYTTYACNATHTCNCCNGCNACNYTNGCNGARGAYTTY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CCNGARCCNGTNCARATHCCNGTNGCNCCNGTNGTNTCNAAYMGNCCN GGNGCNACNCCNATGMGNCCNCCNACNGTNGGNCCNGGNMGNAAYCCNAAYCCN------ ATHCCNATHMGNCCNAGYGCNCCNYTNATHGCNMGNACNYTN------------------ ------------------------------------------------------------ ------TCNGAYCCNTTYGAYGAYCCNMGNTGGGCNGCNATGAARGGNYTNYTNGARTCN GAYMGNACNGARGARATHGTNYTNGAYGAYAARCCNTTYGARYTNMGNATGGGNAGYTCN MGNAARYTNACNYTNTAYGGNCARYTNTTYGARGTNGGNGTNAAYYTNAARGAYMGNGGN ATHTAYYTNAAYGGNCARYTNGTNTAYMGNYTNGGNGARYTNATHAARGARGTNMGNYTN AAYGGNMGNCCNATHMGNYTNTAYTAYCAYGGNCARTCNMGNCCNATHTGGYTNGAYGGN CARTAYCAYGARATGMGNYTNGAYGCNCCNCCNMGNAAYTTYYTNATHGAYGGNAGYCAR MGNGGNTTYCARATHGAYGGNMGNGAYATGATGYTNYTNGTNGAYMGNATHGARAARGGN AGYTAYGGNGGNCCNCCNMGNAARATHMGNATHGCNGGNGTNGARCAYCAYATHAGYTTY CARTTYCCNCCNAARACNATHYTNATHGAYGGNGARCCNTGYGARYTNAARYTNGAYAGY AARATHCCNTTYGTNATHATHMGNGGNAARMGNCAYGGNATHMGNTTYGAYGGNGARCCN MGNACNATHTAYATHAAYAAYCARCCNTAYGTNATHCCNYTNGAYMGNGCNGARAARATH MGNATHGGNTCNMGNCCNACNTAYATHGCNTTYGGNGGNCCNGCNCAYGARATHATHATH GAYGGNAARTGGTTYGARGTNMGNTTYGAYAAYATHCCNAARGAYATHCAYYTNGGNAAY MGNMGNTTYMGNATHMGNATHCCNGGNCCNCARCCNMGNGTNAARATHYTNGGNGARYTN AAYATGAAYTTYGAYTGYTCNMGNYTNATGACNGCNAAYACNGARGCNCAYMGNGTNATG CCNTCNACNACNYTNCARCARCCNATHCARGGNATGCCN--------------------- ---------------------------------------CCNAGYGTNTCNATHAAYGCN GAYAAYCCNMGNTTYATGCAYCCNGGNYTNCAYGCNACNGCNGGNCCNGTNCARACNCCN AAYGTNGCNAGYCAR--------------------------------------------- ------------------------------------------------------------ ---------------------------------------CCNYTNCARGGNCCNCAYACN GTNATGTCNAAYYTNGGNCCN--------------------------------------- ---------------------------GGNYTNGGNATGGTNCCNCARACNGCNAGYTCN ATGMGNCCNYTNCARGCNGTNGGNATHGGNCARACNTCNCARACNGCNGCNGTNYTNCCN CARCARATHGCNCAYCAYATHACNAAYATHGGNATHCARCARGCNATGTCNACNGTNCCN GCNATHTCNACN------------------CARCCNYTNCARGCNACNATHACNAAY--- ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNGGNATHCCN------------------------GGNYTNYTNYTNAAY CARAGYGCNGCNATHTCNCAYCCNAAYYTN------------------------------ ---------------TCNCARGTNCCNCARCCNTCNATHACNGTNACNTCNGCNGCNCCN GTNCCNTCNGCN---AAYTCNGGNTTYGAYATHAAYAAYYTNYTNAGYAAYYTNYTNAAR GTNGGNYTNATHAARAARGAYTCNGARACNGARATHTCNCCNCARCCNGGNGCNACNAAY CARTCNACNTCNGCNCARGTNCCNATHGTNAARAGYGARAARCCNTTY------------ CCNTGGATHACNAAYAARAARGAYACNATHCCNGAYYTNTCNGAYTTYGAYTCNGAYYTN YTNAARATHTCNTAYMGNAGYGTNATHGARGAYYTNCAYCARGGNATHCARTGYCAYACN TGYTCNGCNMGNTTYACNTCNGARGAYAAYGARAARTAYMGNGCNCAYYTNGAYTGGCAY TTYMGNCARAAYAARYTNGARCARGARATGGTNAARGTNGCNAARAAYMGNAARTGGTTY TAYTCNATHGCNGAYTGGATHCARTAYGARGARYTNGARGAYATHAARGARTCNTCNMGN AGYGCNATHTTYGARCARATGMGNTTYGGNGAYCARAAYATH---------GARCARCAR CAR------------YTNTAYGCNYTNGARGGNAARGARGTNACNAARAAYCCNGTNGCN TCNGGNGTNGARGGNGARGAYATHTGYACNACNTGYGGNGAYCCNTTYGAYCARCARTGG AAYGARGARACNGARGARTGGATHYTNAARAAYGCNGTNAARGTNGAYGGNAARACNTAY CAYCCNATHTGYTAYGARGAYYTNCARGARACNCCNACNCCNGGNCCNGGNGTNGARTCN AAYCCNYTNACNCARGCNATHGCNTCNATHAARCARGARCARACNGARGAR--------- GAYGTNAARCCNGAYATHGARCAYATHAAR------------------------ATHGAR CCNCARGARTAYAGYGTNGTNATHAARAARGARGTNGARGAYATHAGYGGNGARTCNATH TCNAGYATHGAYGCNGTNYTNMGNCCN---------------------------TTYTCN AAYAGYAAYAAYAGYTCNATHCCNGGNATHTCNCCNTCNGTNCCNAAYGTNGCNGCNAAR GGNGARTAYGAYCARACNGCNYTNCARTTYACNTCNGCNYTNACNAAYCCNAARCARGTN ATHTCNATHTCNCARGARGAYCCNAAYGCNCCNTGGGARATGGAYTCNAAYCCNACNCCN GARYTNTCNMGNACNCCNAGYCCNYTNCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GAYAGYGARGARGAR GAYAGYGAYGARTTYACNGARGARGARATHGCNAAYGAYCCNTGYAARMGNATHYTNTGG GCNGCNGARAAYAAYAARGTNGAYATHGTNCARGCNYTNYTNCARGARGAYGCNAARYTN GCNYTNGTNAARGAYAGYGAYGGNTAYACNCCNYTNCAYMGNTCNGCNTAYAAYAAYCAY GCNGAYGTNGCNMGNYTNATHYTNTCNCAYCCNGAYGGNATHAAYGAYMGNACNGTNGAY GGNTGGCARCCNYTNCAYAGYGCNGCNMGNTGGAAYTCNGTNGARACNGCNCARYTNYTN ATHTCNAGYGAYGCNGAYGTNAAYGCNAARTCNAAYGGNAAYYTNACNCCNYTNCAYATG GCNGCNTCNGARMGNAAYAAYAAYAARATGYTNGARYTNYTNYTNAAYAAYCCNTTYATH GAYGTNAAYGTNATHTCNAARGCNGGNGARACNGCNGTNCARATHTGYAARMGNACNAGY GCNCAYTAYTCNATGTTYGAYATGACNGAYATHAGYATGCAYAARYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TGGGAYAGYATHCAYYTNYTNTGYYTNGCNAARACNGAYYTN AARAARGCNACNCARYTNATHGTNAARAARTAYCCNACNGTNATHGCNAAYTTYGCNTCN YTNTGYTTYCARGGNGAYATHGCNAAYTAYGCNTAYGTNYTNACNTGYATGGARAGYATH YTNAARGARTGYATHTCNCARCCNAAYGARAAYGARACNYTNTAYATGAARGCNTAYAAR GAYYTNYTNACNMGNYTNTCNGARYTNTTYCCNCCNTCNCARTTYATHCARYTNYTNCCN AARGAYGGNAGYYTNATHTTYYTNYTNCCNTTYATHACNMGNAAYATHGARYTNGARAGY AGYAAYTCNYTNAARCARGAYATHATHGAYATGGGNAARCARYTNYTNTCNCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GARYTNAARACNAARMGNYTNCCNAARMGNYTNYTNTAYATHYTNMGN TAYGGNGCNYTNAARGARGGNYTNAAYGTNGAYTCNAAYGGNTAYGTNGAYGTNAAYGAR YTNCCNACNYTNAAYYTNYTNAARTGYTAYCCNGTNGAYGARATHYTNAGYGARATHAAR TCNTCNYTNTCNTAYMGNAAYGTNGCNMGNTAYGARTGGAARGARAARAAYGCNACNACN TTYGTNMGNGCNTCNTAYYTNMGNMGNTTYGARCCNAAYCCNTTYCAYCAYGGNACNAAR GTNAARACNYTNYTNGARTCNAGYATGACNTGYATHYTNGAYAAYYTNAGYATGTAYGAY YTNGARGAYTTYCARGAYGARTAYATHATHAARMGNATGATHCAYMGNYTNAARMGNGAR AARACNATHACNAAYCARTCNYTNTCNGTNYTNYTNGTNCCNACNYTNACNMGNGTNGAY YTNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYACNGARTTYGAYTTYGARACNTCNAAYGCN CARTTYGAYAARGAYCAYATHGARAARGARAAYYTNAGYYTNAGYACNAGYGAYAARTCN GTNAAYGGNGAY---ACNGARGAYGAYCCNGARATHGARGARGARGARGGNGARGARGAR GAYCCNGARTCNGTNTAYTAYGAYAARAARAARTCNTTYTTYGAYAAYATHAGYTGYGAR GCNACNGARAARAGYAARGGNCARMGNGTNACNTGGMGNGARGARMGNAARYTNAAYAGY GARACNTTYGGNATHTCNGARAAYTTYMGNMGNAAYTTYMGNGGNMGNGGNGGNTGGMGN GGNGGNAAY---MGNGGNGGNTGGMGNGGNMGNGGNMGNGGNGGNCARGGNGCNMGNGAY GGNGGNTAYGGNGGNGGNCAYMGNGGNGGNGGNGGNMGNMGNCCNGARTGGAGYTAYGGN GAYMGNMGNMGNATGGAYGCNCCNYTNATHYTNGTNCAYACNAAYATHYTNTAYGGNGAR GTNATGATGGARGCNGTNCAYYTNCCNTTYYTNAARAARYTNGTNTTYCAYGAYYTNCAY TCNAGYYTNYTNGAYCAYMGNCARGARAGYAARMGNATGTAYAAYAARMGNGCNACNATH CARYTNTCNATGCAYTGYACNCARYTNGARTGGGTNGARYTNTTYACNATHTGGTCNGAY YTNGAYAAYGAYGTNTAYMGNAGYTTYACNAARAAYTGY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TTYTAYAAYGCNTTYATHAARYTNYTNYTNTCNTCNAGYTCNGAYAAR ACNAAYATHYTNTTYGTNGAYGCNCAYCCNMGNGGNAGYYTNGAYGAYGTNTGGTCNACN YTNTTYGGNAAYTTYTAYMGNGCNGGNMGNYTNCAYAAYCCNGTNAGYTTYGAYAARYTN GTNTGGGGNATGYTNGGNTAYTCNAGYCCNYTNAAYAARCAYGARYTNGARCAYGTNCCN TAYYTNGARGARTTYMGNGAYTTYTTYYTNACNCARCAYGGNATHGAYACNTCNCAYAAY ATHACNTGYAARMGNYTNAARGTNYTNGTNATHTTYMGNMGNAAYTAYGCNGCNCAYCCN MGNAAYCCNAAYGGNAAYATHGTNMGNAARTTYACNAAYGARTAYGARATHGTNGARACN ATHTCNMGNACNYTNGGNTCNCCNGCNTCNGTNATHGGNYTNGCNYTNGAYTCNYTNCCN ATGAARAARCARYTNGARATHGTNGGNGAYACNGAYTAYCCNGCNGAYGTNGARGTNTCN TAYGAYGAYTTYAARTAYGTNGARGCNGTNYTNCCNAARTCNACNGTNCCNGARATHCCN CAYCAYCCNTCNTAYCCNACNCCNTCNGGNTGGGTNCCNCCNAAYGAYGARYTNMGNAGY CARCARCCNTAYYTNGTNMGNMGNACNAARAAYCAYGTNYTNCCNGTNTAYGCNGTNCAR AARGARCARTGGGGNMGNATHATGCAYCAYATHYTNGTNAARMGNATHGARGGNGAYATH TGGACNYTNGARGCNGARYTNMGNCARTTYYTNATHGARAARTAYGGNYTNGAYAAYYTN TAYACNCARGTNCAYGARGTNAGYMGNTGYGTNMGNGTNMGNGGNCARTAYCAYGARGAY ATHGCNCARTTYYTNYTNGAYMGNGGNATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CCN GTNATHATGYTNAARCARCARTAYMGNATGCAYCCNGARATHYTNAARYTNCCNAAYGCN TAYTTYTAYMGNAAYCARYTNGTNACNGCNGARTCNTGYATHYTNTCNMGNAGYTCNGGN YTNMGNCCNTAYYTNGTNTTYGAYGTNGTNGAYGGNGTNGARAAYACNGGNAAYCARGGN TCNAARTCNAAYAARAARGARGCNATGTGYGTNGCNGTNYTNTGYCARMGNGTNATHAAR ATHYTNAARAARACNTCNMGNCAYAARGARMGNCAYATGCARGAYAARATHGGNGTNATH TGYTTYTAYTCNGARCARMGNMGNGARATHCARGARAGYYTNMGNCARMGNTCNYTNTTY CAYATHACNGTNAAYACNGTNGAYAGYTTYCARGGNCARGARAARGAYGTNATHATHYTN TCNTGYGTNMGNGCNCARGGNAAYCCNCARTCNGTNGGNTTYGTNGARGAYAGYAARMGN ATGAAYGTNGCNYTNACNMGNGCNAARYTNGCNYTNTAYATHYTNGGNCAYGGNAARACN YTNGCNACNGCNGAYYTNTGGAARTTYYTNTAYCARGAYGCNGCNAARMGNAARGTNYTN GTNCARGTNGARAARACNGARAARTTYGARGARATHGCN------------AGYAARAAR MGNMGNMGNACNTTYGARYTNGARGARGCNACNYTNAARGGNAAYAAYACNCCNGTNATH GARAAYGARCARCCNMGNGARACNMGNGAYMGNACNTCNAARACNCCNCARACNGARCCN TCNMGNAAYTCN------GCNAARMGNATHMGNMGNGGNACNTAY--------------- ------------AGYAAYAARGTNTCNCCNTCNCAYCARGAYMGNTCNAGYGGNGGNYTN AGYACNCARTCNATHATHGAYTCNGTNAGYAGYGGNTGYTCNAGYGCNGARMGNAARGAR AARYTNYTNTCNGCNATHGAYAARAARGTNCARATGAARATGGCNTCNAGYCCNGCNAAY GTNYTNAARAAYCARAGYAGYCARATHCCNMGNTTYATGGCNTTYYTNAAYAARAARAAR GAYGARACNGTNAAR------ACNCCNGGNGGNAARAAYTGGAARAARATHCAYAARAAR GARTTYTCNAARTTYGAYTCNATHGAYGTNTAYYTNGAYAARAARACNCARMGNAARGAR AAYATGTCNTCNAGYTCNAARAARATHCCNGCNATHAARTCNTCNTCNGCNGTNAAYTCN CAYACNAARYTNGTNAARCCNGTNACNAARATHCCNGARTCNTCNACNATGTTYAARCCN ACNGTNATHTCNACNAARAAYYTNGAYYTNAAYTTYTCNAAR---CCNACNTCN---AAY TCNAARACNCCNGCNAARTCNAARTCNMGNAARCARGCNTTYACNTCNMGNAARCARGCN TTYACNCCNTCNMGNAARCARATHTCNGCNTCNAARAARGTNAARGAYACNAARGCNCCN GCNTCNCCNTTYAARTTYACNGGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGTTYTTY GGNTCNAARTTYGTNTAYYTNGGNAAYGARCARGARGAYGARGARGARGTNAARGTNTCN ACNGTNGAYGAYGTNGTNYTNTCNGAYAGYGAYGTNAGYGAYGAYGAYGGNGARACNTGY YTNYTNGAYATHYTNGAYACNGCNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYGTNGGNTCNAARATHTCNAARATGAARGAYTGYCARMGNTCNAGY TTYAGYGGNAGYCCNGCNYTNAGYCAYCARTCNTCNYTNGTNCARGARTAYGTNGAYYTN YTNGARMGNCARMGNCCNATHGARGAYTCNGAYGCNAARCARGARGCNAGYGGNCARAAY MGNYTNTTYAARGAYTTYCCNMGNMGNACNTCNYTNGTNGAYATGTCNGTNATHACNACN YTNTAYTAYTGYTCNYTNTAYCAYTTYGAYYTNACNGARAAYTCNYTNGGNAGYCCNYTN GCNATHAARAARMGNCAYCARATHACNGARAARCARTTYGTNTGGACNTCNATHTCNGCN MGNGCNAARYTNCAYCARTGGAARGAYATHGARGCNATHYTNACNACNAARGGNTGGTTY GGNGGNACNAARYTNAARTCNGTNATHGGNTTYGAYAARATHGTNGGNATHYTNGAYAAR TAYAARGCNCCNCCNGAYGTNYTNGAYAARTAYYTNGCNYTNATGGAYGAYCCNCARGAR MGNYTNACNYTNGCNYTNAARGTNCARTGYCAYAARACNGTNATHGAYACNTAYGCNGGN YTNAARGAYMGNGGNTCNYTNGARACNTAYGCNTCNAARYTNGAYMGNTAYTCNAARGAY GGNYTNTAYGCNTTYGAYGTNYTNAAYGGNTCNGTNATHAARTGGAAR------------ ---GGNYTNTCNACNTTYATHAARGARACNAARCCNGGNGTNGAYGTNGARACNACNCCN GCNGTNCCNGCNCCNYTNGTNGTNGARMGNAARAARGCNATHGTNAARCCNCARGTNATH ACNCAYGTNATHGARGGNTAYGTNATHCARGARGGNYTNCARCCNTTYCCNGTNCARCAR ACNTGYYTNYTNCARGARTTYATHTGYCCNAAYAARATGAAYGGNYTNGARAARGARTCN GARGARGAYGGNACNAGYCAYGAYGAYGARCCNCCNACNYTNYTNCCNCARATGGAY--- ------------------GTNTGYAGYCCN---------------------------CAR ACNATHATHCAYTCNCCNCAYAARGARGCNGARTGYGARTCNTGYCAYAARACNGCNATH GTNTCNGCNCARATHGGNTCNCAYTCNTTYTGYTCNYTNTCNTGYTCNMGNMGNTTY--- GCNTCNCARTCNMGNMGNGCNGAYYTNYTNAARGCNAARGGNYTNTCNMGNAARMGNAAR CARATHACN---GGNCAYAARGARTGGTCNGGNAARAAYGAYACNTCNCCNTCNTAYTCN YTN------------ATGGARGCNAGYGARCARGARGCNACNCARATGCAYCARGCNCAR GAYGARATGAGYAGYTGYAAYTCNGTNCARGARACNAGYTCNTGYGCNACNTCNCCNTCN CCNYTNTCNATGACNGGNTCNCAYGTNGAYGCNGARACNTAYCCNAAYACNGAYCCNTCN AARTGGACNGTNATGGAYGTNTAYCAYTTYGTNAAYTCNYTNCCNGGNTGYGCNGAYCAY GCNGAYGAYTTYMGNTCNCARGARATHGAYGGNCARGCNYTNYTNYTNYTNAARGARGAY CAYYTNATGACNGCNATGAAYATHAARYTNGGNCCNGCNYTNAARATHTGYGCNAARATH AAYTCNYTNMGNGTNGAYCCNYTNCCNTTYCAYACNTCNAARCCNACNGAYGTNAAYMGN MGNAARGAYMGNGCNGTNATHAARCAYYTNTAYTAYAARGAYCAYGARAARACNYTNAGY CAYGCNTAYAGYCCNYTNGTNGARYTNCCNGAYTAYACNTAYYTNGAYGGNMGNCCNACN GARATHACNYTNGCNGARAARAAYAARCARACNAAYAAYTAYAAYYTNGCNAGYCARGTN GTNAARYTNGTNGAYGARGTNAARYTNGCNCARAAYGARTTYGTNTCNCARCARCARGCN GCNGARCARTAYGARCARGAYMGNCARAAYTCNCARYTNAARGARAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGTCNYTNGARYTNGTNTCNAARTGYYTNGAYYTNGARGAYYTNGCNAARGTNTCNGCN ACNGAYAARACNGGNAARAARAARAAR---GTNAARACNAAYGAYGCNATGAARATHATH AARACNGAYMGNCARGGNGTNTGGAARGARYTNMGNAARGTNMGNAARCARCARYTNAAR GARYTNGCNAARAARMGNAARACNGARAARTTYAARTCNGCNATHGARAGYTAYAARGAY GARCAYGAYGTNGAYCAYACNGAYAGYAAYGTNGARATHYTNYTNAARATGTCNAARYTN GGNAARGTNAARAARGAYCAYGCNCAYAARATHYTNTAYCARCARCCNTGYMGNYTNTCN MGNGAYGTNGARCARCCNGCNGARGARACNGARCCNACNTCNYTNTTYACNGAYGARGAY TTYGARAARTTYGCNAARGARTAYCAYCCN---ATGTCNGTNCCNCCN------GTNGCN GGNGGN------------AAYCARCAR---------------------GAYMGNCARAAR MGNAARYTNYTNYTNGARCAYATHCARGARCARAARAARMGNYTNCARCAYGGNCARCAY TCNTCNGTNGCNACNCCN---CCNCCNGCNGTNAAYACNAGYCCNGGNATGATHGGNACN AGYCARCCN---GCNGGNTCNGGNATHTCNTCNGCNGARTAYGCNACNATHAGYAAYCCN MGNCARMGNACNGCNYTNCARCAYGCNCAYGCNAAYTCNGTNGGNTAYTTYATHACNCAR GAYTCNTCNTTYGGNAAYYTNATHYTNCCNGTNYTNCCNMGNATGCCNGARACNAARACN GAYGTNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GGNGTNATHYTNTAYAARAARATGGAR GAYCCN---TGYGAYATHTGGYTNCARGTNACNYTNYTNGAYATHGAYACNCCNYTNAAR TAYGGNGCNCCNMGNTAYGTNTAYYTNCAYTAYTCNAAR------CAYGCNGGNYTNGAY ATHACNYTNACNGTNGCNAAYAARTCNATGTCNMGNYTNCCNGARTCNYTNTCNTTYGCN TTYACNCCNAARTCNTTYAAYCAYCAYTGGYTNATGGARAARATGGGNTTYAAYATHGAY CCNTGYGAYGTNGTNYTNAAYGGNAGYCARTAYGTNCAYGCNGTNAGYTCNTCNGTNMGN TTYTAYAAYAARACNAAYCARGGNATGAARATHGTNGCNCAYGAYTCNCCNYTNATHCAR TGGGGNACNTCNTTYMGNMGNCCNTCNCCNTTYCCNGTNCCNYTNAARCCNATHCCNTGY GAYGAYATHACNTCNGTNGCNTTYAAYYTNCAYAAYAAYATHTGGAAYACNAAYTAYATH TAYTGGTAYCCNTAYTCNAGYGAYGAYGGNAGYTTYAARTCNMGNTTYAGYATHMGNTTY YTNGCNTCNGCNGAYTTYTTYMGNGARAGYCARMGNMGNACNAGYAARACNGGNGTNGAR TCNACNYTNACNTCNTAYTAYAARGARYTNCARTAYGAYAGYGTNGGNGAYGCNGAYATH CARTCNMGNAARACNTCNTCNTTYGTNMGNGGNGGNATGAARTCNATHYTNCARCCNYTN ACNAARCAYTTYAARCCNGAYACNGTNCARTAYAAYAGYTAYGTNACNCARATHGAYTTY TCNACNTTYAAYAARAARTAYGTNMGNGAYGGNCCNAARCCNGCNGTNATHGTNACNTGY ACNGGNGGNMGNAARYTNGARGCNAGYCAYGTNATHGTNGCNATHCCNYTNGGNCAYYTN AARAAYAARGCNMGNTCNATHTTYMGNCCNTCNYTNTCNCARCARAARYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CCNCAYGTNAARACNTCNCCN AGYCAYACNGCNCCNAGYATHAGYGTNACNGCNGCNGCNCCNAGYTCN------------ ------------GARGAYGGNACNGCNGCNCCNMGNACNACNGGNGTNAAYCARGGNATH TCNAARGARGARTAYAARGCNAARATGGCNGARAARMGNMGNGARGCNMGNGARAARGCN GARAARGARGCNGARGARGAYMGNATHAARCARGARGARGARMGNYTNGCNGARGARGAR MGNCARMGNCARGARGARGARGARCARMGNMGNTAYGARGARGARACNATHMGNYTNTCN CARGARGCNMGNAARGCNGARGARGARMGNYTNCARAARGCNATHGARGCNGARGARMGN MGNAARAARGAYGARGCNGAYMGNYTNGARCARGARMGNAARGTNAARGARGARGCNGAY MGNAARGCNAARGARGARGCNGARMGNATHGARAARGARAARCARGARMGNGCNAARAAR GARGARGARGARMGNYTNGARMGNAARAARAARYTNGARATGATHATGAARMGNGTNAAR ACNGAYCCNACNCAR---------GAYAAYAAYAGYGGNAGYAAYAGYTCNYTNAARYTN GARAGYCCNGCNAARTCNGCNAGYAGYTCNCCNAAYMGNAGYACNGTN------------ ACNTCNCCNGAYATHCARGARGTNCCNCCNTTYGGNGCNGCNTCNTCNAAYCARGAYCAR GAY--------------------------------------------------------- AAYTCNTCNGGNTCNGARGAYGGNCAYGAYAAYAARCARCARAARAGYGCNACNGGNAGY GGNATHACN---------TCNTCNACNGAYAGYYTNGAYAAYGAYTCNTCNGCNCCNTCN TCNCARCAYGTNCCNGTNGTNMGNAGYGCNTCNTCNGGNGAYATHATHGAY------TCN ACNGAYGAYGAYAAYMGNYTNGARAAYGGNGGNAGYYTNGGNTCNYTNAAYGCNAGYAAY AGYACNCCNGTNCAYTCNGARTCNACNAAYTCNCCNGCN---------------GARGTN AARTCNMGNTTYAARTCNCCNYTNYTNCARCAYYTNGTNGARAAYAARGGNTCNGAY--- ---TCNTCNGGNACNCCNAARTTYAARTCNCCNYTNYTNCARAAYYTNYTNGGNAARAAR AARGTNGGNGCNMGNATGAGYYTNTCNGCNAGYYTNGGNGAYYTNAGYYTNAAYAARGAR ------GGNAAYACNAGYGCNAAYTCNGCNAGYGCNAGYACNYTNGGNGCNACNAGYCCN TCNYTNAGYCCNGCNACNTCNAGYAARGARATHTCNAARGCNGGNCARGAYGARGAYAAR GAYGTNGAYGARTCNAAYACNAAYACNACNTCNACNGCNGTNTCNCCNTCNTCNTCNGCN GARTCNTTYAARYTNGARTCNAAYAAYGAYCAYGTNGTNTTYACNAAYGGNGAYAAYTCN GAYGAYGARAARYTNACNCARGAYAGYGGNAGYGGNACNATGGCNGAYTCNGCNYTNGGN GCNAGYATHGAYCCN------------------GCNGAYACNGGNTCNATHTCNGTNATG TAYAAYGGNCAYGGNGGNAARGAYYTNCARCAYACNATGGARGAYTCNAGYATHGGNYTN CAYTCNCCNGTNGARGARGAYAARCCNYTNGGNGTNMGNACNACNACNTCNTCNCARTCN GGNCAYTCNTCNTCNCARGARGARACNGARGGNGGNMGNTTYGARGARTAYATHGAYYTN ATGGARGGNAAYACNCCNAGYAARGTNGCNAAYGTN------TCNCCNATHATHGCNTTY GARGAYAAYTCNYTNMGNACNGCNGAYGTNAGYGARTCNYTNTCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNAAYTCNGARGGNCARATGYTNGARTCNMGNTCNCCNTGGMGN YTNTCNTTYATHACNGAYGGNATHTGGGGNTTYATHAAYTTYATHGTNYTNTTYTTYCAR ACNYTNATHAAYCCNAAYAARAAYAGYMGNGGNGARAAYTAYACNTCNGAYTAYMGNAAR CCNGGNGGNGGNGGNCCNCCNACNMGNMGNATGGGNGGNGTN------MGNMGNGGNGGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNAAYCARATHTAYGARAAYGARAAYAARAAYMGN ACNMGNCCNTGYGTNCARAGYMGNACNGAYGTNTTYMGNATHATGAARTAYGAYATHAAY ACNGCNGGNGARGGNTCNGAYCAYACNCARCCNYTNYTNYTNACNMGNCAYAAYATHGTN CCNGGNATGTTYYTNATHTAYGCNGAYGGNAARYTNYTNTTYTGYGAYCAYATHTTYAAY GGNTAYGGNAAYACNAARACNGAYTTYMGNAARCARGTNATGAARTCNMGNTTYGAYTAY ATHAARGGNTTYTCNYTNCCNCARGAYTTYMGNTTYAGYCCNTCNCARGGNGTNCAYGGN CCNMGNGCNCCNTGGGGNGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNCAYAGYMGNTTYATGMGNGTNCARAAYGAYAAYAAYGGNAARAGYTCN TAYTGGGTNATHAAYCCNGAYGCNAARCCNGGNAARTCNAGYMGNMGNMGNGCNGGNTCN GTNGAYGGNCARCCNAARGAYAARAARMGNGCNMGNAAYAARAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNACNGARAARCAYGARACN TAYCARGCNTCNACNGAYCCNGGNCARATHGGNCCNCARCAYGGNTAYYTNACNGAYCCN AARGGNATHYTNMGNATHGCNGARACNATHYTNGGNYTNATHATGYTNATHTGYGCNTCN ATHGAYTAYTGGTCNCAYYTNGGNGGNGGNTGGGTNCARTTYGTNGCNGTNGCNGCNATG TTYGGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TAYAAYACNGCNYTNGAYYTNYTNYTN TGYTGYTCNTCNGTNATHYTNGCNGCNCCNAARTCNCARACNACNGGNYTNMGNMGNAAY YTNTCNTTYCARACNAARGAYTCNGCNAARAAYGCNGTNATGAARGCNMGNAGYGGNTCN AGYTAYGCNAAYGGNYTNGAYAGYYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TGYCCNACNTGYAARTGYATHCAYGGNGARAARCAYGGNAAYTGYCCNGCNGGNGAR ATGGARTGGTCNYTNATHAARGAYYTNTCNYTNGCNGGNTAYGARAAYTAYGAYACNYTN CARGTNYTNTAYACNATHTCNCAYGGNATHCARGGN------------------------ ---------------------------AARAGYCAYGAYTGYGAYAARGGNMGNATHGTN YTNAARYTNYTNATGGTNACNGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYTCNYTNACNGAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MGNAAYMGNGARCCNMGNGARATHMGNGAYAAYGAYAAYGAYAARMGNCCNCCN MGNMGNCARGGN------------------------------------------------ ------CCNMGNGAYAAYAARGAYYTNAARGCNGGNGAYGARAAYGTNCCNCCNGARTTY MGNGARMGNCCN---GAYAGYGGNTTYAARMGNMGNGARGAYMGNGGNGARMGNMGNGGN GGNTTYGGNGGNGARMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNGGNMGNGGNMGNGGN GGNGARMGNGGNGGNAGYGGNTTY---GGNCCNMGN------------------GGNGAY MGNAARMGNGARTTYGAYMGNCAYAGYGGNACNGGN---GGNGGNATHAARCCNGTNGAR AARAARGARGGNAGYGGNGCNCAYAAYTGGGGNAGYTTYMGNGAYGAYATHGARGARCAR GGNCARGTNAAYCCNGCNGAYGARTCNACNGAYTGGGCNAAYCARCAR------------ GARAARCCNGAYYTNAAYGARAGYGGNGAYGTNGARGTNGTNAAYGARGARGAYGCNCAR CCNCARCARYTNACNYTNGAYGARTGGAARGCNYTNAARACNCARGGNCCNMGN---AAR CCNGARTTYAAYATHMGNCARGCNGGNGARGGNGTNGAYTCNGGNCARTGGAARGARGGN GTNGARTAYCARAARAARATHGARGARGARGARGARGAY---CARGAYGAYGARTAYGAR GARGGNGAYCAYAGYGAYCAYCAYATHMGNAAYAGYAARCARYTNGTNACNGAYATHMGN ATHACNTTYAAYGAYAAYCCNMGNMGNGGNMGNGGNMGNMGNGGNGGNGGNMGN---GGN ATGGARMGNGGNGGN------------------MGNGGNGGNGGNGGNMGNGGN------ ------MGNGGNTTYGGNAAYAAR---AARGARGCNGCNCCNMGNTTYGAYGAYGARTCN GAYTTYCCNTCNYTNYTNAARTCNGCNGCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ACNAARCARTTY TTYATHATHGGNATHAGYGGNACNACNAAYAGYGGNAARTCNTCNATHGGNTCNAARYTN ACNAARTTYYTNCCNAAYTCNACNTGGATHTGYCARGAYCAYTAYTTYYTNGCNGCNGAY GAYCCNMGNGTNGARGTNGARTCNAAYGGNATGCARAAYTGGGARAARYTNAGYGCNYTN GAYATGGAYACNATGYTNAGYGAYGTNTTYMGNTGGATHGAYCARCAYAARTCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNCAYGTNMGNTAYAARAAYAGYAARCARMGNGTNAARGAYCCNAARGTNCAR GTNGAYAARAAYAARAARTAYATHTCNAARAARTCNAARAARAARMGNTCNCARYTNGGN ATHGGNGCNGTNGARGAYAARAGYACNATHATHGCNGAYAARCCNYTNGAYAAYGTNTGG GTNMGNAARTAYTAYCCNCARCCNMGNTTYGARATHGARGARGCNYTNGAYMGNCAYAAR GCNTTYGCNCARCCNGCNATGYTNGAYAAYATGCARGGNGTNACNTAYYTNAAYATGATH YTNGAYTTYMGNACNAARAARCARACNAARTTYATGAARAAYATHMGNTCNACNYTNYTN YTNCCNTTYCCNTTYAGYTGGGGNAAYTCNCCNTCNATHYTNGTNTTYTGYAARGARGAR GARCAYACNAAYYTNGCNATGTCNYTNGGNGCNMGNCAYGCNGGNACNCCNGCNGARGTN ATHAARTCNATHGARACNGGNGTNGTNAAYCCNAARGAYTTYGAYCAYGTNYTNGCNACN GCNGAYTGYGGNATGGARATHGCNCCNGCNMGNTCNTAYTTYMGNGAYAARTTYCCNCAR MGNGCNAARGGNAAYATGGGNACNGAYYTNAAYGARATGTTYMGNYTNTTYTAYACNGGN TAYACNTAYGARTCNCARAGYYTNTCNGAYGCNCARGGNAARYTNCARGTNCCNGTNGGN CARYTNCAYCARCCNACNAAYGARYTNGTNGCNAAYTTYGARGCNTAYATHGCNTCNATH TGYAARCAYMGNAGYATHGCNYTNGGNCCNTTYATHCARTCNATGAGYGTNGTNGCNCCN CCNTCNCCNGARGARTTYYTNGTNMGNGTNGARGARTAYGTNCCNGGNTAYAARAAYGAR GARGTNGAYTCNGAYGAYGARGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARACNCAYGARATGTCNGARTCNGARGAYTCNGAYGCNTCNGCNGAYYTNTTYGARGAY TAYAARAARCCNAARCAYCARMGNGARYTNAARTCNAARGGNATGGARAGYMGNGARAAR GARTAYGARGTNGAYACNGAYATHGAYGARTCNTCNAAYTGYAAYGARGARGGNAARAAR CCNYTNTGYAARTAYGGNAGYAARTGYTTYMGNAARAAYCCNTCNCAYYTNCARGARTTY TAYCAYCCNAARAARMGNAARCAYGARTCNYTNGARACNAGYGCNTCNAGYCCNTGYAAR AARAARTGYYTNAGYGAYGARAARACNYTNCARGCNGTNTTYGARGARGTNCARCCNTTY AGYYTNTTYYTNACNAARGTNCAYGGNATHTCNCARCAYTAYAAYGAYGTNGCNGCNTTY AGYYTNAARGAYYTNYTNTCNCCNGARTGGGGNGARYTNAARTCNTCNTGYCAYTTYAAY TTYATGTTYGAYATHCCNTGGYTNATGGGNCARTAYCCNMGNCARTTYMGNACNYTNCCN GTNYTNYTNGTNCAYGGNGAYCARGGNMGNGCNGARYTNGAYYTNAARGARGCNGCNTCN AAYTTYCCNAAYATHTCNYTNTGYMGNGCNMGNYTNGAYATHCCNTAYGGNACNCAYCAY ACNAARATGATGYTNYTNYTNTAYACNAARGGNYTNMGNGTNATHGTNCAYACNTCNAAY YTNYTNTCNCAYGAYTGGCAYCARAARACNCARGGNATGTGGGTNAGYMGNATHTTYCCN MGNMGN---GCNGAY---AGYTCNAAYGGNGARTCNCARACNAARTTYAARGCNTCNYTN YTNCARTAYTTYGCNGCNTAYGGNACNGCNAARYTNGCNTCNTGGGARMGNATHATHGCN GARCAYGAYATGTCNTCNGCNAAYGTNCAYYTNGTNGGNTCNGTNCCNGGNMGNCAYGTN YTNGARMGNAARCAYGCNTGGGGNCAYTTYMGNGTNAARAARATHYTNTCNAGYGTNGGN CCNGAYCARGGNGTNGTNAARAAYTGGCCNGTNGTNGGNCARTTYTCNAGYATHGGNTCN YTNGGNCCNAAYCCNGARTCNTGGYTNYTNACNGARTGGGGNCARTCNATGTCNGGNTAY MGNAARACNYTNGCNACNAAYYTNCARGCNTCNAARYTNCAYYTNATHTTYCCNTCNAAR GAYAAYATHMGNYTNAGYYTNGARGGNTAYAAYGGNGGNGGNTGYGTNCCNTAYTCNATH AARACNGCNAGYAARCARCCNTGGYTNACNCCNTTYYTNAGYCARTGGAARTCNGARGGN MGNGGNMGNTCNCCNGCNGTNCCNCAYATHAARACNTAYAGYMGNATGTCNCCNGAYGGN TCNCARGTNGCNTGGTTYYTNYTNACNAGYGCNAAYYTNTCNAARGCNGCNTGGGGNGCN YTNGARAARAARGGNAGYCARYTNATGATHMGNTCNTAYGARYTNGGNATHYTNTTYATG CCNTCNGAYTTYGGNAAYAARACNTCNTTYAARGCNAGYAGYCARYTNAAYAARATHACN GAYAARGAYAAYTCNGTNTTYCCNYTNCCNTAYGAYYTNCCNCCNACNACNTAYATHAAR GGNACNAARAARTCNGTNGARYTNTTYTAYGAYGTNGTNTCNCCNTAYACNTGGTTYGCN TTYGARGTNATGTGYMGNTAYAARTCNMGNTGGAAYATHGAYYTNAARYTNMGNCCNTTY TTYYTNGGNGGNGTNATGCARGCNTCNGGNAAYMGNCCNCCNGCNATGGTNCCNAAYAAR GGNATGCAYYTNAAYGARGAYGTNAARMGNTGYGCNAARTAYTTYGARGTNCCNYTNMGN ATHCCNAARAAYCCNGCNGARYTNATGTTYGARAARGGNTCNYTNAARGCNCARMGNTTY YTNACNGCNGTNGAYYTNAARTGYCCNGARAAYGTNGARGCNGTNTCNMGNGARTTYTGG ATGMGNGCNTGGTGYMGNGAYGARGAYYTNTCNGARGAYGARAGYYTNGCNGARGCNGCN AGYAARGCNGGNYTNGAYCARCARGARATHCAYCARYTNATGGCNMGNYTNAARGAYCCN GAYGTNAARGAYMGNYTNAARTCNGTNACNGAYGARGCNYTNGARYTNGGNGCNTTYGGN TCNCCNATGATHGTNGTNAAYGAYAGYGGNGCNAARGARTGGGTNTTYGGNAGYGAYMGN TTYCCNATHYTNGCNCARATHYTNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATHATHTCNCARGCNYTNACNCAYACNYTNATG CCNGCNGCNGCNAARGCNGTNMGNGCNGAYAARTTYGARACNACNCARGARAAYGGNGAR GGNYTNGCNCARCAYACNCARTAYYTNGAYGCNYTNAAYTTYCCNGCNTAYYTNACNCAR CAYAAYTCNATGCCNGGNATHATGCCNGCNTAYAARMGNATHGCNGTNGGNGAYACNATH AAYAARGGNGGNATHCCNYTNTAYCCNGCNGGNCCNYTNATGCAYCCNTAYCARCAR--- ---CCNTCNYTNGTNCCNTTYCARCARCAYCCNTCNTAYATHCCNATGCCNTTY------ ------------------ACNGGNCAYCCNCCNGGNYTNCCNMGNTTYGCNTGYATHGAY YTNACNMGNGAYMGNGAYGTN---GARGTNATHGAYYTNACNCARATGAAYAAYAGYATG GGNTCNCCNGTNGTNATHYTNAAYGCNATGTAYGARGTNGAYCCNAAYMGNMGNCARMGN GGNAGYGGNMGNMGNGGNGTNCAYMGNTCNMGNAGYAGY------------------MGN MGNMGNYTNGCNMGNATHGARYTNCCNACNTCNCCNCCNGTNTCNGCNCCNTCNTCNTCN ACNMGNGAYAAYAGYGARGAYGARGARYTNCCNGAYATHCCNTTYGAYATHCCNCARAAR AGYAARGARGCNAAYGCNAGYTTYGTNAARTCNCCNCCNYTNTCNATHTCNTGYCCNATH TGYYTNGAYGAYYTNAARCARYTNAARTCNGAYAARAARAARATHATGTCNACNGTNTGY GGNCAYATHTTYTGYCARGAYTGYATHAARGGNGCNATHTCNMGNCARAARGCNTGYCCN ACNTGYMGNAARACNYTNAARCCNTCNATGATHCAYCCNYTNTTYYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TGYMGN ATHGGNYTNTAYYTNGAYGCNYTNGAYGCNMGNCCNGAYAARACNACNACNGTNGGNTCN CARCAYGCNTTYATGATGTCNGTNATGGAYMGNYTNCARGARTTYYTNAARGCNATHGAY YTNACNMGNGTNAARGGNGGNATGGARGCNMGNCAYATHGGNGAYGGNGTNATHYTNGAR GGNGTNAARCAYAGYTGYATHATHGCNYTNACNTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNGCNGGNAARATGAARYTNAAYATHCCNAARCARYTNGGNTGYAARYTNACNGTN GARAGYYTNTCNYTNATHAARTCNAAYGARAARATHGAYMGNAARGGNMGNGTNTGGGAR GAYGGNGARGTNCCNTCNTCNCAYAGYGARGAYTCNAAYAARGARGAYAGYGAYTCNGAY AAYGAYGGNGGNGTN---TCNGARACNGGNTCNATHAAYTCNGARAARGAYTGGAARCAR AGYTCNTCNTCNAARCAYAARAAR------AARCAYAARCAYAARCAYAARMGNAARAAR AARAARAARTCNAGYAARGARAARGAYAARGARAARAAR--------------------- ------------------------------------------------------------ ---------GAYGTNGARGGNAARGAYGGNAARAARGAYAARGARAARGAYAARGAYAGY AARACNGAYAARGAY---------GARGGNATHAARTCNGAYAARGAYATHTCNTCNGCN AGYTCNAARGAYAARTCNACNTCNGAYAGYGGNAARACNAARGGNAARAGYTCNAGYAAR MGNACNGAYAARATHGAYAAYAARAARAARGAYAARGARMGNMGNAARCAYGARMGNTCN MGNTCNMGNTCNCCNAARAARTCNAARAARTCNMGNTCNAARAGYAARMGN--------- TCNMGNAARAGYGCNAGYCCNAARMGNTAYMGNTAYGAYGARTGGGAYGCNMGNMGNTAY AGYGAYAGYTCNAARMGNTCNMGNTCNCARMGNAAYGAYMGNTCNAARGARMGNGAYMGN TCNAARGARGAYGGNGCNCAYGAYYTNMGNYTNCARATHGAYAARGCNAARYTNMGNAAR ATHGCNATHGCNAAYACNYTNAAYACNATGAARATGGGNCARCCNGTNCCNGTNCARGTN GAYGTNGCNACNGTNAARTCNGGNGGNAARTCNGTNGARGARYTNACNGAYTTYTGYAAR MGNATHTCNGARAARGAYCAYGARMGNCARGARAAYGCNATHAGYGAYAGYAGYGARGAR GAR---CCNGTNCCNAGYGARGAYGAYACNYTNATHCAYCAYCCNTTYAARGTNAARGAR GCNACNACNAAYATHGTNATGAAYATHMGNAAYGCNAARCARYTNCCNGTNYTNACNCCN TCNGARAARCARGCNCARCARGCNACNYTNMGNATHGCNTTYCCNGTNTCNAGYGGNACN CAYCAYMGNGCNAGYGARTCNGARTGGGTNCCNGTNGARAARACNACNGCNCCNGCNACN TCNATHACNACNATHGCNACNATGTCNCARGCNTCNACNACNGCNAAR------------ ---CCNGARACNACNAAYAGYATHTTYCARACNCCNGGNCCNAAYGTNGAYATHGGNAGY ATHATHTCNGARMGNYTNCARGCNGTNMGNAARYTNCARCARAAYCCNTAYGAYGTNCAR GCNYTNAGYTCNATGCAYAARTCNCARGARAARGCNAGYMGNTGGGCNCARTCNAARTTY YTNCCNGGNCARTTYACNGGNAGYACNGGNGCNCARGTNATGTCNCARCARGARATHATH GGNGAYAARMGNCAYCARGCNTGGGTNAARAAR------------------------ACN CAR------------------------------TTYGGNTGGAARCAR------------ ------------------------------------------------------------ ---------------------GGNMGNAARGGNYTNGCNACNGCNGCNGAYAAYCCNMGN GCNMGNCCNCARCARGGNCCNMGNGCNYTNTCNCAYAARCAYCCNGTNTCNGCNYTNATG GARYTNTGYAAYAARMGNCAYTGGTAYCCNCCNTCNTTYACNGTNGTNTCNGARATHGGN CCNGCNCAYAARAARTGYTTYATGTTYAARGTN---AAYYTNACNGCNACNGTNGGNGAY ACNGTNAARYTNCCNTGYGTNGTNMGN---AAYGCNGAYGAYAARGTNGTNTGGYTNGAY GARAAYGARATHYTNYTNACNTTYCARGAYAARMGNYTNATHGAYGAYGAYMGNTTYAGY GTNATHMGNCCNGCNATGTCNTTYTGGAAYYTNMGNATHMGNAAYGTNMGNYTNAAYGAY CARGGNTAYTAYTAYTGYCARACNAARATGGTNCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYACNTCNYTNMGNATHTTY ACNTGYCCNATHMGNGAYGCNMGNTCNTGGAGYGARACNGGNATHTAYCCNGGNACNGTN YTNTAYGARATHTTYGGNGTNATHATHTCNGGNCCNACNAAYACNAGYTGYGGNATHGGN AARGARTTYTAYATHMGNGAYCARTCNGCNACNATHYTNTGYGTNTTYTAYGARATHGAY MGNGARATHCCNACNATHGARAARGGNCARGTNCAYMGNGTNGTNGGNTCNATGGTNATH AARCAYGGNGAYYTNAARATHGTNTCNYTNMGNCARGCNGAYAARAARGAYAARYTNATH TGYCARCARTCNACNGARYTNTCNYTNGAYGARATGGAYAARTGYGARMGNCCNGGNYTN CAYTTYTGYAAYTTYGAYMGNGAYGGNAAYCCNMGNATHCARTCNYTNATGCARGARGGN GAYACNTCNATHTTYGAYATHGCNAARTCNYTNTTYGCNCAYCCNTGGAAYTAYGARACN ACNTTYTCNTTYTCNTTYCARTTYAARATHTCNAARGTNATGTAYGAYMGNAGYATHCCN AARCARGAYYTNYTNTTYAARTCNAARYTNACNTAYATHGGNAARACNTCNTTYCARATG GCNCARCARTTYTTYGTNAARTCNATHGARGARCCNGTNYTNGARTCNYTNCAYTAYATH GTNTGYATGAAYGARGARACNMGNYTNCCNMGNCARYTNCCNTCNTGGATGGCNCAYMGN TTYCARCARTCNGGNYTNCCNGTNCARATHCCNAARATHGARACNTTYGCNMGNCCNCAR CARACNTTYGTNTAYMGNGTNTGYGTNGCNTGGTCNGAYACNGAYATGAAYAAYCAYTGY AAYTTYGCNAGYTAYGCNAARTAYGCNGAYGAYGCNGTNCAYGCNGCNGTNMGNCARMGN GARMGNGGNAGY------------AAYCARGCNTCNGAYGAYMGNACNGARGGNAAYCCN GCNACNACNYTNCAYGGNGTNACNAGYCARCAYYTNAAYAAYGGNGTNAARCAYTTYMGN GTNGGNTTYTTYAARGARTGYYTNGARGAYGAYGTNYTNGAYGTNCAYATHTGGCARGAR GCNGGNAAYGGNAGYGAYACNAARTCNTCNGTNGARAARAAYGAYGTNGTNCARATGGTN YTNGARTAYTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CARGCNGARGARYTNGGNTGY GARGGNAARGTNGARGARTCNCARGGNGTNATGAARYTNGTNGAYCARYTNAARGAYGAR MGNCARTGYYTNGARATGCARGCN---CAYAAYGARGAYGGN---GGNCCNATGATGAAR CARATGGARGTNTGYGARGTNTGYGGNGCNTTYYTNATHGTNGGNGAYGCNCCNCARMGN CARGAYGARCAYYTNATGGGNAARCARCAYGCNGGNTAYGCNCARGTNMGNAAYGARATH GARMGNMGNAARCARAARACNMGNGARGARATHGARYTNMGNGARGCNAAYGARAAYAAR GTNAARYTNGARMGNGARGGNMGNGARAARGARMGNCARMGNGARMGNGARGARMGNMGN GTNAARGARAARGAYTCNGGNMGNGGNGAYMGNGAYMGNAAYGAYMGNGAYAARGAYACN AAYACNMGNGAYMGN------------GAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNAAYCARYTNGTNGARTGYCARGARTGYCAYAGYYTNTAYCAYCARGAR TGYCAYAARCCNCCNGTNACNGGNCARGAYGTNAGYGAYCCNMGNTTYGTNTGGTAYTGY TCNMGNTGYACNAARAGYTTYAARAARATGYTNGCNCARAARCCNGTNAAR---CCNGCN AARCCNACNATHCCNYTNTCNTCNTCNATHAARGARTCNACNTCNTCNATHTCNAARCAY AAYAARGCNGARTCNGAYACNGGNAGYCARGCNTTYMGNMGNATHGAYCCNAARGCNATH GTNACNCCNAARGAYACN------------MGNCCNTCNAARGGNATGGTNGGNYTNGCN GGNYTNGCNGCNAAYYTNACNAARCCNMGNGGNGARTCNAARATHTCNTCNTCNYTNAAR AARTCNGARCAYAARGGNGAYACNGCNAARTCNTCNMGNCCNGAYACNGGNACNAARACN YTNYTNTCNTCNTCNATHAARAAYGARAAYMGNAARGCNGAYYTNAAYACNAARTCNTCN ACNAAYAARGARGARGGNAARAARAARTCNGARTCN---------GTNAARYTNAARCAY GAYGAR---------AARAARACNACNGAYAGYTTYACNAGY---------AARAARGAR GARAARAARGARAARACNAGYYTNATGAGYAARAARGARGARAARAARGARACNACNGAY AGYYTNATHAGYAARAARGARGARAARAARGARAARACNGARYTNCCNGCNGGNAARTCN CCNAARTCNGGNTCNTCNCCNGGNAGYAGYGGNGGNGGNTCNAAYTCNCCN--------- AGYAGYGGNGARTCNYTNAGYAGYAARAGYAGYAAYAARCARGCNATGGCNAAYYTNTCN ATGGTNACNGCNAAYAARMGNYTNCARATGATGAARAARAARGCNCARACNAARCCNCAY GARAARATHGTNCAYATHAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYCAYGTNGTNATHGTNGGNCCNGAYACNGCNAAYAAR ATGTCNTTYGTNTTYCARGCNGCNGTNTCNGCNGCNACNAGYGGNTCNAARGTNGTNCAY ATHTGYACNCAYCCNATHTCNMGNYTNCCNACNCCNATHCAYGGNATGCCNATHCCNGAR CCNGCNGTNATGAARAAYGTNGAYTTYYTNTAYTTYGARGARAGYACNGARYTNATHTCN TAYTTYGCNGGNATHCAYGTNMGNAARAARYTNCCNAGYTTYATHATHGTNGARGAYATH YTNTCNTAYGCNTCNCARAARCARGAYAARCCNGTNGARAARAGYYTNGCNCAYYTNYTN GCNYTNATHTCNGAYGCNMGNAGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNATHCARATHAARACN GCNGAYGARGAYGARGTNTTYMGNMGNATHGARTCNTTYATHMGNAAYAARMGNAAYGAR GTNAAYGARMGNAAYATHMGNGARTTYATHTCNCCNTCNGAYTCNGAY---GAYAAYAGY TGYGCNMGNGTNGAYGCNGTNTAYATHCAYMGNGARGGNATGAARAGYCAYATHAAYYTN AARACNGTNGARAAYGCNTAYGGNCCNCARACNMGNYTNMGNCCNCAYATHAAYCCNGAR ACNCARGCNTGGGARATGCCNGCNGAYGTNCARMGNGCNGARGCNYTNGARGARMGNATH GCNAAYATGGARGCNCAYYTNAAYATG---TCNGAYATHYTNGGNCCNAGYAGYMGNATH AARACNYTNGARGARMGNATHAGYTTYYTNGARGGNATHTCNCCNGARTAYTTYACNAAY GGNYTNCCN---------------------------------------------TCNATH ATHCCNACNAARCARACNCARTTYGARATHGGNGGNCAYAAYACNGAYATHGTNGTNAAY AARTTYGARGAYMGNYTNTTYATHATHGTNACNCARTAYCARAARATHGGNACNYTNATH GARGTNTCNMGNGAYGTNATHTCNGAYGARGTNCARGGNYTNATHCCNATGTTYTCNACN AAYGTNATHYTNGGNAARGAYGARCCNYTNACNCAYGTNATGGCNAARACNATHGTNACN GCNYTNAAYCCNCCNGTNCCNGTNYTNYTNGGNYTNGCNYTNAARGTNACNTCNMGNGAR GCNATHCARACNATHATHGARCARATHAARTCNTGYYTNATGGCNACNAAYATGCAYTTY GARGCNMGNMGNMGNCARATGGTNATHGAYAARGCNCARATHGCNAARGARAARATGACN TTYGCNCARCARTCNAAYAARAAYGCNGCNGTNGAYGARTCNTCNTCNAAR---CCNGAR ACNATHGTNTGYACNGAYCARGGNCARTTYTAYCARACNMGN------------------ ------------------------------------------------------------ ------------------------------------------------------GCNGGN TAYAARGTNCCNCAYAARACNYTNATHTCNYTNATGTTYMGNTTYGCNGAYGARMGNGGN CARATHAGYYTNGAYAAYTTYYTNGCNYTNATGGCNMGNYTNATGAARACNTTYAAYACN TTYAARACNTCNCARMGNGARGGNGTNGCNTCNTTYTCNYTNGAYCARTGGYTNGAYMGN TCNYTN------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGCCNAAR TTYTAYGARGAYGTNGAYGAYCCNAAYACNAARCCNAARMGNGCNTGYGARGGNATHMGN GAYGAYYTNYTNGAYTGYYTNYTNAARAGYGAYTGYTGYMGNAARGARAARAARACNCCN MGNGARTGYATG---------AAYMGNGTNGAYGAYCCNTCNGTNCCNGAYGARTGYTAY MGNYTNMGNGTNGCNTTYTTYGARTGYAARMGNTCNATGYTNGAYATGMGNACNMGNTTY MGNGGNMGNAARGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARGGNGGNGAYGGNGAYGGNAGYYTNTCNAGYGGNGAR GGNGCNGCNATHGGNATHTTYGTNATHATHTGYATHYTNGGNGCNGGNATHGGNATHTTY GTNTGYTAYMGNMGNAAYAAYATGACNACNMGNAGYTTYMGNGARTTYATHACNGGNGGN GTNMGNTAYAARACNTAYACNAAYGCNACNTAYAARGAYGAYGARGTNGTNATGAGYTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY GARCARGGNYTNGTNAAYCAYATHCAYYTNATGTGYGAYMGNCAYYTNGAYCARYTNATH ATGTGYTCNYTNTAYYTNATHGCNAARGTNACNGAYACNGCNYTNACNTTYCARAAYATH ATGAARTGYTAYMGNYTNCARCCNCARGCNCARAGYCAYGTNTAYMGNAGYGTNYTNYTN CARGAYMGNCAYMGNCAYAGYTCNGGNAGYAGYGAYAGYAGYAARAGYAAYTCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNTTYGTNGCNGCNCAYGCNGGNGCNGGNAAYCAYTCN AARAARGAYGARGCNCAYGTNMGNTGYYTNTGYAARYTNACNTGYCARTAYGCNGCNGAY YTNATGACNAAYAARAARAGYGCNATGGARGCNGCNGARGARGCNATHATGTCNYTNGAR AAYGAYGARAARACNAAYGCNGGNTTYGGNTCNAGYATGACNGARMGNGGNGAYGTNGAR TGYGARGCNAGYATHATGGAYGGNMGNACNYTNMGNTAYGGNGCNGTNGCNGCNYTNACN GGNGTNAARAAYGCNATHACNGCNGCNACNYTNYTNGTNACNGAYCAYGAYAARGGNCCN YTNCCNTAYGGNMGNATHMGNCCNAGYATHYTNGTNGGNAARGGNGCNAARMGNTTYTGY CARGAYMGNGGNATHGAYACNAARTAYAAYAAYATHTCNAARGCNGCNYTNAARACNTAY ACNMGNTAYAARMGNAARTGYCAYYTNCCNGAY---------MGNCCNCCNGARAARMGN MGN--------------------------------------------------------- ---------------------------------------GGNGARGGNMGNYTNAARTCN ------CAYGAYACNGTNGGNGTNATHTGYATHGAYGARGARGGNAAYATHGCNGCNGGN TCNTCNAGYGGNGGNATHTGGYTNAARYTNCCNGGNMGNGTNGGNTCNGCNTCNGTNTTY GGNGCNGGNTGYTGGGCNCARAAYCARACNGAYYTNGGNGARCCNGGNGTNGCNGTNGTN ACNTCNGGNTGYGGNGARCARATHATHCCNACNYTNYTNGCNAARACNTGYGCNGARAGY ATHCARCAYGCNGARTAYACNTCNGARGCNYTNTCNGARACNTTYAARGAYGARTTYYTN GARTCNAARTTYYTNACNTCNTAYCCNAARAARATGGGNGGNGTNYTNGCNGTNAARTAY ACNGAYTTYCCNGARGGNMGNAARGTNGARGTNACNTGGGCNCAYTCNACNCAYTCNTTY TGYATHGCNTTYGTNGGNGGNGAYCARAARTAYGCNCAYGGNYTNATGTCNMGNATGGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AAYCCNYTNATHMGNTTYATHATHACNAGYGCNGCNGGNATHATHTTY GGNATHGCNYTNGARAARGGNMGNGTNTTYGARCCNCARGTNATHMGNGAYCARATGYTN TTYAARMGNTTYGGNATGYTNAARATGTTYYTNTCNGCNACNGCNATHGGNATGYTNTGY TTYTCNYTNYTNGCNGCNYTNCCNCARACNATGMGNAARTTYGGNYTNGCNYTNCARAAY TTYCCNGAYAARAGYGGNTTYAARACNGTNTAYGGNGTNATGGCNGGNTCNGCNYTNYTN GGNTCNGGNATGTCNATHGCNGGNGCNTGYCCNGGNACNATHYTNGTNCARGTNGGNACN GGNGTNCCNAAYGCNTGGYTNACNGTNGTNGGNGGNYTNTTYGGNGCNACNYTNTAYGCN TTYACNGAYTCNTCNYTNTCNTTYTTYAARCARAGYMGNMGNCCNAAR---TGYYTNTAY ATGAAYGAYTAYTTYCARGTNTCNTAYYTNCARYTNGCNATHCCNYTNTCNTGYGTNATG GCNTTYGTNGTNYTNGGNYTNGARTAYTTYTCNCCNTGGGARACNGARGTNGAYGARTCN YTNYTNACNCCNGGNYTNATGAAYGCNGGNGTNTGGCCNCCNTTYYTNGCNGGNATGATH ATHGGNTCNYTNCARATHCCNACNATHYTNGCNAAYGARGAYGGNYTNGGNTCNGCNAAY AGYTAYGTNACNGTNGTNTCNCARATH------GTNCCNCCNGCNATHAAYAAYCARTCN AGYCARMGNTAYTTYAAYCAYTTYAAYGCNGGNATHTCNAAYTGGTGGCARGTNTTYCAY GTNGGNTTYGCNGTNYTNGGNGGNTAYATHTCNTCNCARTCNTCNGGNACNTTYGCNACN GTNGARGGNGTNGARGCNTCNGARGCNTTYATHGGNGGNATGATGATGYTNTAYGGNGCN MGNYTNGCNGGNGGNTGYACNAGYGGNCAYGGNYTNAGYGGNTTYGGNYTNYTNTTYATG ACNTCNTTYGCNGCNGTNCCNGCNATGTTYGGNGGNGGNATHYTNACNGCNTTYTTYATG AARAAYGTNYTNGGNATGTCNATG------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CAYAAYGTNTGYMGNYTNYTNGARCARGARAARTCNAAY CAYAARGARYTNAARCARACNTGGACNYTNGCNAAYGARCARTTYATHTCNACNCAYACN YTNATGCAYGAYGARATHACNMGNATGMGNAARATHATGAGYGCNCARCARYTNGARCAR YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TCNYTNGAYTCNCAYCCNACNATHGAYYTNTCNGAYTTYCCNACNYTNAGYAGYMGNGCN TCNACNACNCCNAAYCCNYTNCCNTCNACNMGNAAYTAYGTNGGNATGGTNAGYAARCCN GCNCARGAYTCNGCNCCNGARTTYAAYATHTCNCARGARGARTTYCCNGCNYTNCCNGGN TCNCARAAYCCNCCNGTNAAYTCNGGN---AGYGARTTYMGNGGNMGNGGN------GGN GGNMGNGGNMGN---GGNCCNCCNMGN---GGNGGNTTYMGNGGNGGNMGNGGNGGNGGN AGYATGGAYMGNGAYAGYGGN---GGNGGNMGNGGNGGNTAYMGNGGNGGNTTYTCNMGN GGNMGNGGNGGNCCNCCNMGNAGYMGNGAYGAYTTYTCNCCNCCNMGN------ATGTCN MGNAGYTTYGARGTNTCNGAYMGNGARMGNGGNCCNCCNGCNGARMGNMGN---GAYMGN TTYGAYGAYAGYTTYGAYMGNGGNACNACNATHMGN---------------TAYACNTCN CCNYTNMGNGAYACNGGNMGNAGYTTYGAYMGNCAYTCNTCNCCNCCNCCNCCNMGNMGN GAYMGNGAYTTYATGCCNMGNAGYGAYMGNGAYTAYACNACNACNTCNTCNMGNTTYTCN CCN------------CCNCCNGCNMGNGAYTCNYTNTAY---TCNTCNTAYAARGAYACN TAYACNTCNGTNMGNMGNGARGARMGNMGNCCNCCNMGNGAYTAYCCNCCNMGN------ ------------ACNACNGAYTAY---GARMGNMGNGAYTTYMGNGAYGCNCCNAAR--- GARTAYACNGCN---CCNMGNGAYTAYGCNCCNTCNTCNAGYMGNAAYGGNGAYTAYMGN GAYTCNYTNAGYAGYMGNGAYTTYMGNGAYTCNTCNMGNGGNGAYMGNTAYAGY------ ------------GGNGGNGGNGGNGGNAGYMGNGGNGGNMGNGGN---MGNCCNAGYTAY GAYGAY---------------------------------------------------MGN CCNCCNMGNGAYTAYGGNGGNMGNGGNGGNGGNMGNGAYGAYMGNGGNGGNMGN---GAY GAYMGNGGNTCNAGYMGNGTNAGYTAYATGAAYGGNTTYACN------AGYACNMGNGAY MGN---------MGNTCNAAYAGYMGNGARGGNGCNGGN--------------------- ------------GGNAARMGNGCNMGNATGGAYGGNGGNGAYTAYMGNMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARATHGARYTNYTNTGGGARGAY AARGCNTCNAAYCARYTNYTNGCNAGYATHMGNYTNTAYTTYMGNCCNGARCAYACNCCN GARGGNMGNCARGAYGAYTCNGGNGARGAYGARATHGTNGTNYTNGGNGARMGNYTNGTN YTNMGNYTNGAYGAYYTNYTNCCNYTNYTNGTNGARGAYTTYAARTGGTGYTAYGGNTTY AARGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR MGNCARAAYAARATHTCNAAYYTNGGNACNYTNGCNAARYTNCARGARYTNGTNCCNYTN ACNAARTCNGTNGCNGAYATHAARCARATHGTNACNGCNTTYACNMGNMGNGTNYTNTCN YTNYTNGAR------GARGTNYTNGARGAYCARCARGTNTCNCARGARYTNYTNAARTGY GTNAARGCNTTYTGGTCNATHGTNTCNAGYCARCARTCNGCNYTNTCNTCNYTNCARGGN TGYGTNGGNTGGAAYGGNYTNYTNATHGAYGTNGCNACNTCNYTNGCNTCNGTNTGYGTN GAYYTNTTYATHACNGCNAAYGGNACNAARGARAAYCARTCNYTN------TGGTCNMGN MGNYTNTAYAGYTGGYTNAAYTTYGAYYTNCCNGTNMGNTCNATHAARGTNGCNYTNYTN GARGTNACNGGNCAYGARMGNGAYGGNGCNCARGTNGTNGGNCCNYTNATHAGYCARYTN YTNCARACNGTNTTYGAYAGYGAYTCNAAYCCNGARTAYYTNYTNCAYTTYYTNGTNTTY AARAARTGGCARCAYYTN---GCNGAYGTNGCNAARYTNGARGCNATGTGYMGNTCNATH AARGCNCCNCCNCARTTYGTNGCNTGGYTNAARACNTAYTGGTCNCCNGCNAAYGAYTAY GTNCCNGAYGAYAARAGYYTNGCNGGNTCNAARGTNAGYCARTTYYTNYTNGAYYTNGAY ACNAARGAYGTNTTYGARTCNYTNACNGAYGTNYTNCARATHGTNATHGARGARGTNGAR GARGGNGCNCAYGTNGAYGTNACNGCNGAYACNCCNYTNTTYGTNGTNGAYAARATGGGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARMGNYTNGGNCAYTTYGGNMGNAGYCARTTYTAYATHGCNYTNAARYTNGTN GCNATHGCNCARGCNGGNYTNCCNATHAARYTNGAYTCNYTNAAYTCNGTNAARGARGTN GCNYTNCCNAARTTYGARCARGGNYTNTCNGAYMGNAARAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARTTYACNGAYGARGARATH MGNCAYGARYTNGCNYTNYTNGGNTAYAAYAGYGTNCCNCARGAYAARYTNGARGAYTTY AARMGNGAYYTNATGCAYYTNATHTCNAARGARMGNAGYCARACNAAYTCNYTNAAYAGY AGY---------------------------MGNGTNTCNGAYCCNGAYGTNGARGARGAR AARCAYAAYYTNGARACNGARAGYTAYAAYAAYCAYGCNAGYCARACNGAY---GGNAAR ACNTAYAAYGARAAYTGGTAYTAYCARGGNATHMGNGCNGCNACNTAYAAYGARAAYTGG CAYTAYCARGGNATH---------------------------CARTCNGCNGARACNAGY CCNACNTTYTCNMGNMGNAAY------------------AAYTAYTAYAAYYTNCCNTCN MGNCCNAARACNTCNCAYTCNMGNGARAAYCARAGYAAYTGYATGMGNGAYGAYATHTCN TCNAGYTCNGAYAGYMGNTCNATGAARMGNAARACNTCNMGNAARGCNTCNGAYGGNTGY MGNCARGTNGAYGARTCNTTYTCNGAYACNAAYGCNGGNYTNTTYGARATHTAYGARMGN ATHMGNAAYYTNGCNYTNMGNGARTGYGARTGYGGN------MGNAARGGNAARAAYGAR YTNGARCCNCCNTAYMGNATHAAYGGN---AARAAYAARAAYCCNTCNGTNATHMGNAAR AARGARCCNCCNCAYACNMGNAAYYTNATHMGNACNAAYATHAAYGARMGNCAYAARATG TAYAAYGAYGTNTGGAARGCNCARCCNCCNGTNGGNGAYGAYMGNMGNYTNAARYTNMGN AARGCNATHCAYGCNAARATGATGAARCAYCARGAYATHAARYTNAARCARAARATHTAY GTNCCNAAYTCNTAYGTNCCNCCNCAYGARAARYTNMGNAARGAYGTNMGNTGGAARGTN AARCARGCNTTYGARAAYTAYGARYTNCCNAAYACNGGNTTYTAYCAYGAY--------- ------------ACNYTNAGYTCNAARACNAARCARYTNCAYAARGCNAAYAARGAYTGG AAYGAYCARTGGAAYACNYTNAARMGNCARACNGARGARGARAAYGTNAARYTNAARGCN CARGTNAARCARYTNGTNCARGARAAYGAYCARYTNMGNMGNCAR------------YTN GARTCNCARAAYGAYGARYTNYTNCAYYTNAAYYTNGCNAARAARGARYTNGARAARTCN AAYAAYGTNYTNATGTCNGGNMGNACNCARGARAARCARYTNYTNGARAARYTNMGNCAR GAYTAYGGNACNYTNCAYCARCARAARMGNGCNYTNGARGTNAARYTNGARGGNYTNATH TCNAARAAYAARGCNGAYCCNMGNCARGARGAYAGYTAYAAYAARACNAARGARACNGAR YTNGCNGTNATHAARMGNCARGTNACNYTNTTYATGGARGAYTTYAAYAARGARCAYGCN GARMGNYTNTCNYTNGARAARAARYTNAARAARGARAARGARACNAAYCAYAGY------ ------YTNGAYTCNAARYTNAARMGNACNCAYGAYYTNYTNAARTCNMGNGAYGARGAY YTNMGNGTNAARTCNAARAARGCNGCNGAYYTNCARTAYCARATHGAYGAYYTNAARYTN AARYTNGARATHGARCARMGNMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNAGYAAY GARGARTAYAARTGYCCNTCNMGNYTNACNGARAARTTYGCNCARYTNGTNATHYTNGAY AARCARACNAAYATHTAYGAYTAYCAYYTNCCNYTNTCNTCN---CCNGTNGTNTCNATH ATHGAYCCNAARAGYTCNAAYAAYTTYTCNGARATHCARGAYCCN---------GARYTN CCNCARCARTCNAAYGCNAARGARGCNAARGARATHATGMGNATHMGNCAYAARAARATG AARAARCAYAARYTNAARAARYTNMGNAARMGNATGTAYTTYGTNTGGAARAARCARAAR ATGGCNMGNMGNTCNAARMGNGAYGCNATHTAYTGGAARGGNATHTCNGAYATHAARAAR GARGGNGAYGAYTTYGAYGCNGARAARTTYGTNAAYAAYCARYTNGAYAARGCNMGNMGN GGNGGNTAYTAYGTNAAYGTNTTYCARTCNAARATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARMGNTAYAGYAARAGY GTNYTNACNGGNGGNTGGAAYCARGTNTAYYTNACNATHGGNCARGAYTCNTAYYTNAAR ATGTAYAARAARCARGGNGAYTAYACNCCNCARYTNACNATHTGYATGAARGAYGTNGCN AARTAYTTYGCNTAYGGNGARTAYACNAAYGGNATGCCNGAYMGNCCNGCNYTNCCNCCN GGNACNTCNACNAGYTGYATHATGGGNATHCCNACNAARCCNAGY--------------- ------------------------------------------------------------ ------------------------------------------------CARATGATGTCN ATGGTNAARGGNYTNTTYYTNYTNATHGTNGCNAGYYTNATHTTYCAYTGYGTNGTNGTN YTNTTYGGNGCNCCNGTNTAYACNTCNGTNACNGARACNTTYCAYTTYGCNGTNATGYTN ACNGTNYTNGTNGTNYTNCCNTGYTAYGCNGTNACNGGNAAYAARYTNGAYAARYTNGTN CAYATHTTYACNTCNGARAGYMGNGAYCCNGGNYTNGARACNGTNGTNTAYYTNACNACN ATHGGNTCNGTNYTNGGNGCNTGGYTNGGNGCNGTNCCNATHCCNYTNGAYTGGGAYMGN CCNTGGCARGTNTGGCCNATHAGYTGYTCNATHGGNAGYGTNTGYGGNTAYTGYYTNGGN YTNTTYATGTCNTCNYTNTAYYTNCCNCAYCARTAYAARATHGCNGTNAARCARAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNGTNCAYAARCAYYTNGAYATHYTNAGYTTYTAYTAYGGNGGN TGYGAYYTNTGGTGYCCNMGNCARTAYTAYAARGARATHATGGARGARTTYCCNACNYTN GAYGCNMGNYTNTGYGAYYTNAAYATGAARCAYGCNTTYGTNATGYTNMGNAARGARGGN CAYAARATGGCNGAYATHYTNTGGGARTGG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATGGCNMGNGGNATGAARAGYAARAARYTNCAYGARGTNTCNMGNATGGCNTCNGTN GTNGCNAAYATHGCNAARCARACNAAYTGYGAYATHGTNATHGAYGTNGGNTCNGGNYTN GGNTAYYTNGAYCAYGTNYTNCAYCARYTNTAYGGNYTNGTNGTNYTNGGNYTNGARTCN GARCARAGYCAYGCNTCNGCNGCNGARAAYMGNGCNGTNAGYCARGGNATHACNTGYGGN GGNATHAARAGYATGCARTGYCAYATHGAYGAYAAYGARGARTCNTAYACNAAYTTYGTN AARAAYATHGARGARGTNYTNCCNAGYYTNAGYTGYGARTGYGARAARMGNGTNCARAAY CARAGYGAYMGNGGNGGNMGN---MGNGCNTGYYTNATHGGNYTNCAYTGYTGYGGNGAY YTNTCNACNACNYTNATGTCNTAYTTYAAYTCNTGYCARTTYATHAARGCNATHTGYTGY GTNTGYTGYTGYTAYCAYAARATGATGTAYTCNAAYGAYACNTTYCCNAARTTYCCNYTN AGYTCNAARGGNAARAARTCNTAYCARCARTCNATHGAYGARCAYGGNAARCCNTTYATH TCNCCNTTYTCNYTNMGNYTNGGNGCNCARGARACNMGNTAYMGNTGGCARCARCARTCN GARGCNGAYCAYCAYTCNCAYACNAAYCAYGTNGGNTTYMGNGGNATHYTNAGYTTYACN AAYGARAGYGAYGCNCARATHMGNCARAARGTNMGNCAYTGYAAYTTYGARTCNATHAAY AGYTTYGTNGARTCNTAYTAYGAYTCNTCNGARGTNGAYAARMGNTCNCAY--------- ------YTNYTNTCNGTNTAYGARGAYTAYAARACNCAYTTYGAYGGNATHGARATHYTN ACNYTNYTNCARGTNATHYTNCARCCNGTNATHGARACNYTNATHTAYCARGAYMGNTGY GARTGGYTNAARGARCARGGNCAYACNGAYGTNMGNATHATGCCN--------------- ---------------------------------------GTNTGYCARCARTGYGTNCAR AAYGTNTCNAARGCNGAYGGNYTNGGNATGAGYAARYTNYTNTCNAARGARTTYAGYGAY CARYTNMGNGAYGCNGCNAARAAYGTNACNCARAARYTNGAYYTNATHTCNGARATGYTN TCNAARCARTGYAAYGCNGTNYTNGCNCARMGNATHMGNMGNTCNTAYCARATGYTNYTN YTNTAYMGNAAYYTNTAYGGNGARMGNYTNYTNAARGARAARGTNAGYACNCARATHAAY MGNATHAARAARAARCCNYTNATHGCNGTNYTNTCNGCNTCNATHTTYAAYTGGGAYMGN GARMGNATHTCNGAYGARGARGTNAARMGNTGYTAYAARGARGTNGAYGARGTNCAYMGN YTNGTNAGYGCNCCNGTNMGNAARCARGGNGCNAAYAARACNGTNACN------------ ---------------------------AAYTCNCARGGNCARTGGGARCARGTNGTNGAY AARGARGAYTTYAARGTNTGGMGNCAYCARYTNCCNAAYTCNGARYTNTAYCARTAYMGN GTNYTNGGNCAYTTYAARGAYYTNCCNGCNMGNGCNTTYTAYAAYACNCARGTNGAYGTN CAYTAYTGGAARGAYTGGGAYACNCARACNATGGAYGTNMGNGTNGTNGAYAARGAYACN CCNTCNGGNACNGARGTNATHCAYTGGYTNTAYTCNTTYCCNTAYCCNATGTAYCCNMGN GARTAYGTNTAYGTNMGNMGNTGYATGGTNTAYCCNGAYAARAAYTGYATGATHATHACN GCNMGNGCNACNAARCAYCCNAARTGYCCNACNAAYAARACNTCNGTNMGNATHGARACN TAYAARTCNCARATGATHATHACNCCNAAYAAYAAYTTYGAYGARAAYGGNTTYACNTAY GTNATGTCNTAYTAYGAYGAYCCNCARACNAAYTTYCCNCCNATGTGGTAYAAYTGGGTN GCNAGYGCNGGNGTNCAYGARTTYYTNCARMGNYTNCAYAGYGCNGCNYTNAARAARCAY AAR------AAY---GTNMGNYTNACNGCNAGYACNACNGAYCCNAAYTCNTCNATHTAY TCNGGNATGCCNCAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGCNGAYMGNGTN GARCCNCCNCCNTTYGAYAAYGAYGARGAYGARATHAARGAYGARGAYGAYYTNTTYGCN GAYGCNAARGARAAR---ACNTCNCARGAYGCNAGYCCN------GTNGARGCNATGAAY GGNGAYGTNTCNGAYACNYTN---GARAARGAY---GAYGAYGAYGAYYTNTTYAARGGN GGNAGYTCNGARGTNAARYTNGARTCNGAYGARGARGARGARGCNCCNGTNGCNAAYAAY AAYGCN---------------------------------------------TCNAARGTN GARCARCCNGCNGCNGCNGCNAARGARGTNACNCCNGARATHTCNGTNTCNGARGTNATH ACNGCNAARACNAARATHGCNGCNCCNTCNYTNAARGCNGAYGARTTYTCNGAYGAYAAY ---GAYGARAARGARCARTAYGARYTNGARATHMGNATHACNGARAAYYTNAARATGGGN GAYGGNATGTCNGCNTAYATGGTNTTYAARATHGTNTCNAARACNTCNAAYCCNGCNTTY MGNACNCCNGARAAYACNGTNYTNMGNMGNTTYAGYGAYTTYYTNGGNYTNTAYGCNAAR YTNGCNGARAARCAYGTNCCNYTNGGNATHATHGTNCCNCCNGCNCCNGARAARAGYGTN ATHGGNATGACNAARGTNAARATGTCNAARGARGAYACNGCNTCNATHGAYTTYATHGAR MGNMGNAARAARGCNYTNGARMGNTAYYTNATHMGNACNGCNGCNCAYCCNGARYTNGCN GCNGAYCCNGAYTTYATHGARTTYYTNGARAARGAYGGNGAYYTNCCNAARGCNACNAGY ACNTCNGCNYTNAGYGGNGCNGGNGTNATGMGNYTNTTYCAYAARGTNGGNGARTCNATH GARAARATHACNYTNAARGTNGAYGARAGYGAYGARTGGTTYGARGARAARCAYCARCAR GTNGARGCNYTNGAYAGYCARYTNAARAARYTNCAYTCNAGYYTNGARACNYTNGCNGCN CAYMGNMGNGARYTNTCNGGNTCNACNGCNGTNTTYGCNAARAGYGCNGCNATGYTNGGN AAYGTNGARGARCAYACNGCNYTNTCNMGNGCNYTNTCNCARYTNGCNGARACNGARGAR AARATHGARATHGTNCAYAARGAYCARGCNGARGTNGAYTTYTAYACNATGTCNGARYTN ATGAARGAYTAYGTNGCNYTNATGGGNGCNGTNAARGGNGCNTTYCAYGARMGNATHAAR GTNTAYAARAAYTGGAARGAYAGYGARACNATGYTNGGNAARAARMGNGARAAYAARGCN AARYTNGARYTNGCNGGNAARTCNGAYAARYTNCCNCARGCNMGNACNGARATHACNGAR TGGGARCARAARGTNGARAARGGNCARGARGAYTTYGARAARATHTCNAARACNATHMGN AARGARGTNGCNMGNTTYGARAARYTNMGNGTNTCNGAYTTYAARGCNAAYGTNATHAAR TAYYTNGARGTNYTNATGGARAAYCARGARAARYTNATHAARTAYTGGGARACNTTYYTN CCNGARGCNCARGCNATHGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARGGNMGNMGNGTNTAYTTYTTYMGNAAYGGNGAYATHCAYTAYAARCCNAARCAR GTNYTNATHAGYAGYMGNACNTAYCARAAYTTYGARAARYTNYTNGTNGAYYTNAGYTCN ATHGTNGARACNTCNACNGGNGTNAARTAYATHTTY------------------------ ------------------------------------------------------------ ------------GARGGNTGYGAYAARAGYTTYMGNTTYCCNGCNGTNYTNAARAARCAY ATGAARATHCAYACNGGNTAYAARTGYGAYYTN------TGYGAYGAYGTNGTNGARACN TGGACNYTNYTNMGNAARCAYAARTCNGARATHCAYTCNTCNGAYCAYGTNTGYTAYACN TGYCARATGGTNTTYTCNTCNAARTCNAAYYTNACNGTNCAYYTNCARTGYCAYTAYAGY CARGCNGARTCNTTYGARTGYCCNMGNGARGGNTGYACNMGNACNTTYAARTAYAARAAR AAYATGAAYCARCAYATHMGNGCNTAYCAYGARGGNGARMGNGTNTTYCCNTCNAARGAY AARGTNGARMGNGARMGNAARMGNYTNACNGCN---TCNAGYTAYMGNAARATHAGYCCN GCNGCNMGNYTNAGYGGNATHGAYGAYMGNYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CCNCCNGGNTAYCAYCCN---------------GGNGCN YTNGCNCCNGTNCAYCCNAAYTAYACNCCNGTNCCNCCNCARTCNMGNTGGGCNMGNYTN MGNGAYGTNACNTTYGCNTCNGTNATHGTNGCNGGNGTNTCNTAYGGNYTNTAYCARYTN TTYAARAARTAYATHATGCCNYTNATHGCNGGNTCNAARMGNCARGARAARMGNATHGAY MGNYTNGARYTNGARGTNGCNGARATHCAYAARTCNGTNAAYCARTCNYTNTCNGARATH AGYMGNACNYTNGCNGCNATHCARYTNAGYATH---AAYAGYCARGAYCARCARCCNGCN GCNTCNCARGTNGGNMGNGGNATHACNGAYYTNAARGCNGAYATHTCNTCNYTNMGNAGY YTNYTNYTNAGYAAR---------------------CARACNACNGAYATHTCNGCNAAR ATHGCNMGNTGGTGGMGNCARAARMGNATGCARGGNYTNGCNGTNGARYTNCCNAARTGY AAYCCNAAYTCNATHYTNTAYCAYATHTCNMGNYTNCCNGARTGYCARGGNTTYYTNYTN AARGARAARAARMGNYTNYTNCAYYTNYTNCARACNGGNMGN---AARGARTCNGAYATH TAYGCNGCNYTNGCNAAYYTNGARGAYTAYGTNGGNAAYACNTCNTCNAGYYTNGTNTAY ATHCARCARGGNYTNGARYTNGAYCCNACNAAYMGNAAYAAYYTNTGGYTNAARGARAAR ATHTCNMGNCARTGYGAYACNYTNMGNAARCARACNGTNGCNAARGARAARYTNAARAAR GAYCARYTNTAYTTYCCNCARATHACNCARGTNCARMGNGTNTCNGCNAGYGGNATHAGY ATGGCNGARTTYAARGAYAARTAYYTNAARGCNGGNACNCCNGTNATHYTNACNGAYGTN GTNCARAAYATGTCNAARGTNACNTTYGAYTAYTCNYTNATHGAYGARCAYGCNGGNAAR ACNGTNGTNTCNACNAARCARACNGTNAARGARTCNACNACNTGGGCNAARYTNGARAAY AARMGNGARATHACNGTNGCNCARGTNATHAARGAYATHCARGAYGGNTGYGCNAGYGAY TGYYTNTTYGAYTGGAGYYTNCCNYTNCAYTGYCCNAGYYTNAAYCARYTNATHACNYTN CCNGAYTTYTTYAARGAYAAYGTNYTNYTNCARACNTCNCCNGGNTCNYTNTAYMGNCAY AGYTGGCCNAGYYTNTTYATHGCNCCNAARGGNGTNATHACNCARYTNCAYGTNGAYGCN TTYCAYTCNCAYTTYTGGATGGCNYTNTTYAARGGNCARAARMGNTGGACNTTYTTYGAY GARAGYGAYACNTCNYTNYTNTAYCCNCARYTNTTYCARTCNATGGAYCCNGTNTTYCAR GTNGAYYTNACNAARCCNGAYYTNGAYMGNTTYCCNYTNYTNTCNYTNACNATHCCNCAR CARTGYGTNYTNCARCCNGGNGARYTNYTNTTYGTNCCNGCNGGNAGYCCNCAYATGGTN GARAAYYTNACNAAYTCNYTNGCNATHTCNTCNAAYTAYGTNGAYCARTCNAAYYTNAAR AARGTNTGYCARCARYTNMGNATHAAYTCNYTNCARGAYGARMGNGCNGCNGAYYTNYTN TCNCARYTN---------------------------------AARCARMGNGCNGTNATH GARTTYYTNTCNTAYGARGGNTCNAARCCNYTNGAYATHCARGTNMGNYTNAAYAAYGTN TAYGGNGAYGCNGCNGTNGGNATHGAYACNGCNMGNMGNTGGGTNAARAARYTNAAYGGN GGNGAYCCNGARACNACNGAYYTNNNNAAYYTNGARMGNGTNNNNMGNCCNYTNACNGCN ACNGAYCAYCARCARCARYTNNNNGTNGAYNNNYTNATHCARAAYAAYMGNMGNATHACN CARMGNACNATHTCNCARCARGTNGGNATHTCNYTNGGNAGYGCNAAYAGYATHATHAAY AAYGTNYTNAARTAYAARAARGTNTGYTCNMGNTGGGTNCCNMGNAARYTNACNGARGAR ATGAARCARAAYMGNAARMGNATGTGYNNNNNNNNNNNNNNNNNNNNNNNNNNNAARGTN AAR---------AARYTNYTNAARTGGAARATGAGYCCNATHACNCCNYTNGTNGTNAAR ACNGCNYTNTCNMGNGTNGGNTTYMGNATHACNAARMGNAAYCAYGAYTGGYTNGGNTGY TTYGGNAARCAYATGAARGCNYTNTGYTTYAARCCNYTNMGNGARTAYCARAARYTNAAY CAYTTYCCNGGNTCNTTYCARATHGGNMGNAARGAYMGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CARGARGARTCNTTYGARTTY ATGMGNGGNGTNATGGAYGARTGYACNCAYYTNGGNAAYTTYTCNGTNCCNGTNGAYCCN GARYTNGTNATHATHGTNGCNGCNACNCARGAYGCNTAYATHCCNMGNGAYGGNGTNYTN CCNYTNGAYAARYTNTGGCCNGGNAGYGARGTNMGNTAYATHGAYCARGGNCAYGTNGGN GCNGTNYTNYTNCAYCARGGNGTNTTYMGN------------------------------ ------------YTNGAYCCNAAYATGYTNCAYGAYTGYMGNGAYTAYTCNAGYGAYACN GGNATHAGYAARMGNGTNTTYTCNAARGARAGYMGNGTNMGNYTNATHGAYMGNGTNAAR AGYAGYATHTCNCCNGAYYTNMGNTCNMGNYTNYTNTCNGAYAAYAARAAYATHTCNATH CCNGCNAGY--------------------------------------------------- ------GARAAYGCNTCNTGYAARTAYAGYCAYMGNGAYTGYACNCARCCNTGYYTNGAY GGNTAYAAYTAYTGYYTNMGNCAYATHYTNGARGAYAARACNGCNCCNTAYMGNCCNTGY GCNTAYGTNACNAARTCNGGNMGNAARTGYACNTCNGCNGCNCCNAARYTNGAYAARAAR GARGTNTTYTGYGCNTCNCAYACNAARAARGCNATHYTNGCNMGNCARMGNTTYTCNMGN AARMGNMGNCCNAARGARACNTCNGAYACNYTNYTNGARGAYYTNGTNTCNTCNACNTCN TCNYTNGAYTCNAAYCAYTCNGTNGARCAYMGNMGNGGNAARATHCAYAGYGAYAGYYTN GCNGCNAARTCNYTNGARTAYGCNAGYTCNACNGAYTCNGARTCNGARTCNATGYTNGTN GARCAYGCNTGGMGNGAYTCNGGNGAYAGYGAYGCNGAYAGYATHGAYAGYGAYCARGAR GAYATHYTNAARTAYGCNGGNATHTAYACNACNGARGARGCNGCNCARATHYTNMGNGAY AARYTNATHMGNYTNCARGCNYTNTAYATHGAYCARTTYAARMGNYTNAARCAYATHYTN YTNACNAARMGNAARAARTAYYTNGARGCNMGNAARATHGARAAYAARYTNTAYGGNAGY ATGAAYMGNTAYAARGARGAYCCNGARCARMGNGARYTNTAYGAYAARYTNTGYGCNATG AARMGNTAYCAYAARAARTTYGGNATHGARMGNYTNGTNAARCARCARTCNACNCARMGN MGNYTNAARGTNACNGARGGNATGGAYGAYAARYTNACNACNCARATHAARTGYACNTTY ACNGAYGARGGNGTNGGNTGYTCNCARCCNGTNGTNCCNYTNAGYAARTTYTGYCARAAR CAYATHYTNCAYGAYCARCAYCARGTNYTNTAYCARCCNTGYCCNTTYGCNGAYAGYCAR TGYGGNMGNCCNGTNGCNACNYTNYTNGGNAGYCCNTTYTGYTCNYTNCAYCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CARGARTTYCCNGTNATHACNGARCARGTNGARATHGAYAARCAY GTNYTNATHGARMGNATHGTNMGNYTNCARAARTCNCAYGCNMGNAARAAYGARAARYTN GARTTYYTNGGNGARCAYATHCARCARYTNYTNACNGARATHAARAARAARACNAARATH ATHCARAGYTAYGTNATGMGNGARGARGCNGGNACNYTNTCNTCNGARGAYTCNGAYGCN AAYAARYTNYTNTCNMGNAARGGNGGNATHATGGCNTCNGTNTAYTCNYTNCAYCARCAR ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARGCNCAR GGNGGNAARGAYGARACNTTYCARACNTTYGTNYTNCAYGAYGARGAYCAYACNATHGGN AAYGCNYTNAARTAYATHYTNAAYAARAGYCCNGAYGTNACNTTYGTNGGNTAYAGYATH ACNCAYCCNTCNGARAGYAARATHAAYYTNMGNATHCARACNTCNGGNAARCCNGCNGTN CARGTNTTYAARCARGGNYTNAARGAYYTNAARCARYTNTGYGGNCAYATGYTNACNACN TTYGARTCNTCNACNAARTAYTAYAARGARAAYCAYYTNGAY---------GARATGGAY CARTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TCNAARTCNAARTCN GCNCCNACNAGYAARCAYGAYMGNMGNTCNAARMGNCARTCNAARGTNGAYACNAGYATH GARACNCAYTCNGARTGYTCNAAYGARATHACNGARGGNGCNAARTCNTGYAARAGYMGN CARAARYTNGCNATH---CCNYTNGCNATGTGGGAYTTYGARCAYTGYGAYCCNAARAAR TGYAGYGGNAARAARYTNAGYMGNYTNGGNTTYGTNMGNACNYTNMGNYTNAAYCARMGN TTYGGNGGNYTNATHYTNTCNCCNATGGGNTCNAARTGYGTNGCNCCNGAYGAYMGNCAR TTYGTNGARGCNAAYGGNATHGCNGTNATHGAYTGYAGYTGGGCNAARYTNCARGARACN CCNTTYGGNAARATGAARGGNGAYAARYTNMGNYTNYTNCCNTAYYTNATHGCNGCNAAY CCNATHAAYTAYGGNMGNCCNTGYAARYTNTCNTGYGTNGARGCNTTYGCNGCNACNYTN TAYATHACNGGNTTYGTNGAYGARGCNGARATHYTNYTNGGNAARTTYAARTGGGGNCAY ACNTTYTTYTCNATHAAYACNGARYTNYTNGARAGYTAYAGYAARTGYATHACNAGYCAR GAYGTNGTNAAYGARCARACNAARGTNYTNGCNMGNTTYCARCARGAYAGYGTNGAYGAY AARATGAARGAYTGGATGYTNATGGAYGCNGAYGTNGAYGTNTGYAAYCCNAAYMGNCCN YTNTAYCCNCCNTCNGAYTCNAGYTCNGARGARGARTCNGAYGARGARGARGARGAYGAY GARGARGAYGARGAYGARGARGARGARGAYGAR------------------GARACNGTN CARAARATGGCNATGGARTGYGCNAGY------CAYGAYYTNTCNTTYATGATGCARYTN GGNGARYTNGCNCARAARCARGAYGTNAARGARMGNACNAAYTTYGTNTGYGAYCAYGTN CCNAARYTNACNGAYYTNGCNATGTGYATGATHAARAARGTNTCNGCNTGYGTNCCNGCN GARGCNAARCCNATGATG---AARGCNATHCCNAAYAARGAYMGNATHATGGAYGCNYTN AAYTAYATGTGYGARGAYMGNTCNGTNGTNTCNGAYCARTGYYTNGCN---AAYAAYGTN YTNGCNATHTCNCARTGYTAYCARCARAAR---------ATHACNCARATHGTNTCNGTN ATHTCNCCNGCNGAYAAYCCNATHAARACNGTNTGYACNATHATHCAYGCNGARGARAAR TGYTTYACNGARAAYAARGGNACNTGYAGYGAYTAYTAYATHTCN---------MGNYTN GTNGGNACNGTNGARAARYTN------TTYCCNAARTCNGTNTGYGGNAAYGTNAARAAY AARAAYATHYTNAAYAGYATHYTNATHCAYGGNCARCCN---ATH--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYTCNYTNTTYYTNTTY ATHGCNGCNGTNYTNAAYGTNGTNTCNYTNATHTAYATGCAYCARTGGCARCCNACNACN GARTCNYTNATGCCNTAYTTYATHATHATGGGNACNTGGGGNGTNACNGAYGGNTTYTGG ACNGCNCARGTNAAYAGYYTNATGGGNGTNATHTTYCCNGARAARTTYGARGARGCNTAY AGYGGNYTNMGNATHACNCARGGNYTNAGYGTNGCNGTNGCNTTYGGNTAYTCNAGYATG YTNTGYATGACNGCNAARATHTAYATHACNGCNGCNGTNTGYGTNGTNGGNYTNATHGGN TAYYTNATHATGGARGGNYTNGTNAARTTYGGNAGYAARAAYAARGCNATHYTNYTNAAR CARACNTCNGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNCCNCAYTAYAARGGN MGNAARMGNYTNCAYYTNGARTTYAARGARGCNGTNACNMGNTAYGGNTCNGAYATHAAR CARMGNATHATGGAYTCNYTNAARAGYACNTGGACNAGYATHAAYGAYTTYGCNAARGCN CAYAARTCNGARGGNAARGARATGGAYACNCARGTNCARTCNGARGTNGAYCARATGATG AARCARATHTCNCARCARCAYGTNGAYGAYGAYACNGCNTCNGTNTCNTCNATGGCNGAR GARGARATHCARATHGGNCARYTNAAYGARGGNCARMGNGTNGAYCAYCARYTNCARGAR GGNCCNYTNGARTCNTTYAAYGAYTAYYTNTTYGCNYTNACNTCNCAYTCNTCNTAYTGG GAYTCNGARGAYACNGCNYTNYTNATGYTNAARGARATHTAYATGCCNMGNATHGTNGGN CCNCCNCCNCCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GGNTAYGCNAARATHAARCCNCAR TTYYTNYTNGTNAARGAYAARCCNCARATHCARCCNGARAAYYTNAGYGCNGAY------ ------------GAYAARAARMGNAARYTNGARGTNTCNAAYGAYGCNAAYGARTCNGCN AAYAARAARAARGCN---------------------------------------AARGGN MGNAAYAARAARMGNCCNCAYACNGTNAARATHGARAGYAAYGAYAARYTNTGYCCNGCN ATHAARGAYGGNAARGAYTGYAARTAYGGNGAYAAYTGYAARTAYAAYCAYGAYYTNAAR GTNTAYATHGARCARAARATGCCNGAYATHGAYGGNAARTGYCCNGTNTTYGARAARYTN GGNTTYTGYMGNTTYGGNATHACNTGYMGNTTYTCNAGYAGYCAYATHGGNGARAAYATG GARAAYYTNGTNAAYAAYGAYATHTAYGAYAARATHAARGAYAARCCNYTNTCNYTNAAY GCNYTNACNGARGARGTNMGNAAYAARYTNTGGAARMGNAARTAYGAYTTYTCNAARGCN YTNACNTCNGTNAARGARGCNCAYCAYGTNMGNAAYGGN--------------------- ------------------------------------------------------------ ---------------AGYCARAARGTNGARATHGARGCNCCNYTNGARGTNGARGCNCCN YTNGTNYTNGAYACNGARCCNAARAAY--------------------------------- ------------------------------------------------------------ ------------------ATHGAYGAYGTNTAYATHCARCCNACNCCNMGNGARGTNAAR AARATHGAYTTYMGNAAYAARATHTCNYTNGCNCCNYTNACNACNGTNGGNAAYYTNCCN TTYMGNMGNGTNTGYAARTCNTAYGGNGCNGAYATHACNTGYAGYGARATGGCNYTNGCN TCNCARYTNYTNAARGGNAARGGNGCNGARTGGTCNYTNATHAARMGNCAYGCNAGYGAR GAYYTNTTYGGNGTNCARYTNTGYGGNGCNTTYCCNGAYATGATGTCNAARTGYGCNCAR GTNYTNGTNGARACNTCNGAYATHGAYTTYATHGAYATHAAYTGYGGNTGYCCNATHGAY YTNATHTTYAAYAARGGNAAYGGNAGYGCNYTNATGGGNAARGCNACNAARYTNGARCAR ATHTGYMGNAGYATGAARGGNGTNATGGGNGARAARCCNYTNACNGTNAARGTNMGNACN GGNATHATGGAYCAYAARAAYAAYGCNCAYAAYYTNATHCCNMGNYTNMGNGAYGCNGGN GTNTCNYTNGTNACNATHCAYGGNMGNTCNMGNGARCARMGNTAYACNAARYTNGCNGAY TGGAAYTAYATHGAYGARTGYTCNGARATHGGNAAYCCNATGCCNGTNTTYGGNAAYGGN GAYGTNYTNTCNTAYGARGAYGCNAAYYTNCAYATGAGYMGNAAYAARGTNTCNGGNGTN ATGATHGCNMGNGGNGCNYTNATHAARCCNTGGATHTTYACNGARATHAARGARCARMGN CAYTGGGAYATHTCNTCNTCNGARMGNTTYGAYATHYTNAARTCNTAYACNAAYTAYGGN YTNGARCAYTGGGGNTCNGAYCAYCARGGNGTNGARAAYACNMGNMGNTTYATGYTNGAR TGGYTNTCNTTYYTNCAYMGNTAYATHCCNGTNGGNGTNYTNGAYCARGTNCCNCARAAR ATHAAYGARAARCCNCCNTAYTAYATHGGNMGNAAYGAYYTNGARACNATGATGGCNAGY ACNAAYTGYGCNGAYTGGGTNAARATHAGYGARATGYTNYTNGGNCCNGTNCCNGAYAAY TTYYTNTTYYTNCCNAARCAYAARGCNAAYTCNTAYCAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GGNATHACNGGNTCNGGNAARACNTAYACNATGACN GGNTTYCCNCARGAYCARGGNATHYTNCCNMGNTGYYTNGAYGTNYTNTTYAAYAGYATH GGNGARMGNCARGCNAARAARTAYGTNTTYMGNCCNGAYCAYATGAAYGGNTTYGAYGTN CARAGYGARGCNGAYGCNATGYTNGARMGNCARAARAARGAYATHYTNCCNGGNYTNACN TCNGGNAGYAARACNTCNYTNAARMGNGGNGAYAGYGGNGAYACNGAYMGNYTNATHGAY CCNACNGTNGTNGARGGNGTNGARGAYGAYAAYAAYTAYTCNGTNTTYGTNTCNTAYATH GARATHTAYAAYAAYCAYGTNTAYGAYYTNYTNGARGAYYTNCCNTAYAAYGCNATHACN GGNTAYAARCCNCCNCARTCNAARATHYTNMGNTCNGAYTCNTCNGAYAAYATGTAYGTN CAYAAYTGYACNGARATHGARGTNAARCARCCNCARGAYGCNATHGAYGTNTTYTAYMGN GGNCARMGNMGNMGNAARGTNGCNCAYACNGCNYTNAAYGCNGARTCNAGYMGNAGYCAY AGYGTNTTYAAYATHMGNYTNGTNCARGCNCCNYTNGAYAAYMGNAGYGARGARGTNGTN CARGAYTCNAAYMGNATGTGYACNTCNCARYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARGARCARYTNGCNACN YTNAAYTCNGTNYTNCARAAYCARAARGGNGARCARGGNCARGTNTCNCARYTNATHMGN GAYCAYGARTCNGCNYTNGCNATHAAYMGNCARYTNCARCARGARAARGAYTCNAGYYTN ATGYTNGCNGARCARMGNYTNCARGARTGYCARGCNYTNAARACNGARYTNTCNGCNCAY AARGAYAARGTNTTYAARYTNGARMGNGARYTNGARMGNYTNMGNAGYCAYYTNATHGAR ATHGARGARGGNTAYACNATHGARGCNYTNGGNGCNGARGARMGNGARAARGARYTNMGN AAYMGNYTNGCNGTNGCNGARGARCAYYTNTCNTCNACNTCNTCNCAYGTNAARYTNGCN AGYCARGARGCNCARMGNMGNATHGARAGYYTNGARTCNCARYTNCAYCAYATHGCNAGY CARMGNGAYGCNGCNTAYATGCARGTNGCNCAYACNCARGARCARTGYCARCARTAYGCN TCNTCNYTNACNAAYYTNCARYTNGTNYTNGARCAYTTYCARAARGARAARAAYTCNGCN GTNGCNYTNGARACNGARAARTAYCARGARCARGCNAARACNYTNGAYGGNAARGTNAAR AAYYTNGARAARGARYTNGAYGCNACNMGNACNGAYYTNTCNGAYGCNYTNGAYGGNYTN GARGCNGCNTCNMGNYTNAGYGARCARATHGAYMGNAARGARGARGCNYTNAARGCNYTN AARGARGARGTNCARYTNMGNGARCARTCNYTNAAYGCNGCNGARGARGARATHMGNCAR YTNAAYGCNAARMGNGARGCNAARGTNGAYAARGARYTNATGCAYAAYATGGTNATGACN TGGYTNACNTCNCCNGARAARAARMGNCARGARATHGTNCARYTNATHGGNCAYGTNYTN GGNTTYAGYCCNGARGAYTTYTCNMGNATHCARTCNGCNCAYAGYCARAAYAGYYTNTGG ATHGGNTTYTTYAAYMGNTCNGGNAAYACNGARCCNACNACNCCNACNTCN------AGY CARACNTTYTCNCARYTNTTYGTNAARTTYYTNGARAARGARTCNTCNCCNGCNCCNGCN CCNGTNCARYTNCCNGTNGARGCNATGGCNGCNGARGCNCARAGYMGNCAYAARCARACN TTYAAYCCNTTYATGGCNCCNMGNCAYGTNTCNCAYTCNAGYGAYGGNGCNAARTCNTCN YTNGTNGGNTCNTCNCAYYTNYTNYTNCCNCARGAYAAYATHCAYCCNTCNCCNYTNTTY GCNCCNGTNACN------AGYGGNTAYGGNGARAGYGCNATHYTNAARGAYGTNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARAAYMGN YTNYTNGAYGARGARGGNTCNGGNAGYAARGGNTTYATGGTNGAYCARACNTCNGGNAGY GGNTCNGGNCARGCNAARYTNGTNTGYMGNACNGTNGGNAARGARATHCARYTNATHGAR AARATHGGNAAYGGNMGNTTYGGNGAYGTNTGGMGNGGNAARTGGYTNGGNGAYGAYGTN GCNGTNAARATHTTYACNTCNYTNGARGARACNAGYTGGMGNCARGARATGGARATHTAY AAYACNGGNATGYTNMGNAAYGARAAYATHYTNGTNTTYCAYGCNTCNGAYACNATHGGN MGNTTYTCNTGYACNCARAAYYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGYTNTTYGAYYTNCAYGAYTGGCARCARGGNGCNGAYYTNYTNTGYGAYGAYYTNAAY ---------YTNTTYMGNAAYCAYTTYGAYTGYYTNAGYCARTAYTCNAAYMGNATHTCN MGNTGYATHYTNAAYAGYACNATHATGTTYMGNGARAARYTNCARGAYGCNGGNATGGCN GCNCARAARACNYTNCAYGAYATHACNTGYAAYTTYGCNGARAAYATHGTNAAYTGYYTN GARACNCCNYTNAGYAARCAYTGYCCNATGGCNGTNGTNGAYACNATGGTNATGGCNYTN CAYMGNTTYYTNCCNCCNGCNTGYGCNCCNYTNCAYGCNGCNGGNAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGYTNCARGAYMGNYTNGAYMGNYTNCARGAYGCNYTNAAYGCN TAYGGNCCNAAYTCNCARCAYTTYYTNAARGAYTCNGTNTCNAGYCCNTGGGARMGNGCN GTNGCNGCNAAYAARGTNCCNTAYTAYATHAAYCAYGAYTCNGARACNACNCARTGGGAY CAYCCNCARYTNACNGCNYTNATGGAYGCNYTNATHGAYYTNAAYAARATHMGNTTYGCN GCNTAYMGNACNGGNATGAARYTNMGNATGYTNCARAARACNYTNTGYYTNGAYACNGTN TCNYTNCARATGGCNATGGARTCNTTYGAYAAYCAYGGNYTNMGNGGNMGNAAYGAYAAR YTNATGGAYGTNGGNGARATGATHGARTGYYTNTCNACNATGYTNGARTCNTCNGCNAGY CAYCAYCCNGARYTNGTNAGYGTNCCNGTNAGYGTNGAYYTNACNYTNAAYTGGATHYTN GAYGTNTAYGAYAGYGTNMGNAGYGGNAARATHMGNGTNYTNTCNTTYAARGTNGCNATH GTNATGYTNTGYMGNGCNCARYTNGARGAYAARTAYMGNTAYYTNTTYMGNYTNATHGCN GAYACNAAYGCNTTYGCNGAYCARMGNAARYTNGGNYTNYTNYTNCAYGAYTGYATGCAR ATHCCNMGNCARYTNGGNGARATHGCNTCNTTYGGNGGNAGYAAYATHGARCCNAGYGTN MGNAGYTGYTTYGARAARGCNAAYGGNMGNCCNGARATHGARGCNTAYCAYTTYYTNGAY TGGYTNAARYTNGARCCNCARTCNATGGTNTGGYTNCCNGTNYTNCAYMGNYTNGCNGCN TCNGARACNGCNAARCAYCARGCNAARTGYAAYATHTGYAARGARTTYCCNATHGTNGGN TTYMGNTAYMGNTGYYTNAARTGYTTYAAYTTYGAYGTNTGYCARAGYTGYTTYTTYTCN GGNMGNAARGCNAARAAYCAYAARYTNACNCAYCCNATGCARGARTAYTGYACNACNACN ACNTCNGGNGARGAYGTNMGNGAYTTYTCNAARGTNTTYAARAAYAARTTYAARTCNAAR MGNCAYTTYAARAARCAYCCNMGNMGNGGNTAYYTNCCNGTNGAYTCNCAYYTNGARGGN GAYAGYYTNGARAGYCCNAAYCCNTCNCCNCARCAYAGYATHTCNCARGAYATGCAYTCN MGNYTNGARATGYTNACNAGYMGNATHGCNGARGTNGARCARMGNCARGGNGGNGCNGGN GAYYTN------------------------------------------GARGAYGARCAY CAYYTNATHGCNCARTAYTGYTCNAGYYTNAAYGGNGARCCNAAYTGYCAYGCNYTNAAR AGYCCNATGCARATHATGATGGCNGTNGAYGCNGAYCARMGNCAYGARYTNGARGCNATG ATHCARGAYYTNGARGAYGARAAYAARACNYTNCARGARGARTAYGAYMGNYTNCARATG GCNGCNTCNGARMGNGTNTCNGAYCARTTYMGNYTNTCNGGNAGYGAYMGNGGNAAYACN TCN---------------MGNGAYGAYGAYATGATHGARGARGCNAARYTNYTNMGNCAY CAYAARGGNMGNYTNGARGCNMGNATGMGNGTNYTNGARGAYCAYAAYGCNCARYTNGAR TCNCARYTNGCNMGNYTNMGNCAYYTNYTNCARCARGCNCCNGGNGAYAARAGYTTYATH TCNYTNGAYTCNTCN---MGNGCNACNCCNYTNAGYACNCCNTCNTCNTCNCARAGYTCN TTYAAYATGGGNTCNACNAAYTAYMGNYTNGCNCCNCARATGGARTCNACNCCNCARTCN AAYGGNCAYATH------AGYYTNACNGAYGAYCCNGAYYTNAGYGGNATHATHGGNAAR GTNAAYAGYCCNCCNCARTAYAAYGCNAARACNAARCCNGGN---AAYGTNGGNGAYYTN TTYAAYATHGCNGGNGARYTNGGNGARGCNGTNGGNTCNYTNGTNACNGTNATGACNGAY GARGAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGGCNGCN CCNATGGAYAAYACNTCNTAYYTNCCNTGYGAYGAYTTYATGAARTTYCARGAYGCNYTN AARAAYYTNMGNATHYTNGAYGAYMGNATHATHCAYGCNYTNAAYAARAAYATHCCNACN CARTCNTTYMGNGGNCARGTNGAYGTNGCNGCNAAYTGYAARCAYATHTAYGARGAYATH GARAARTCNTAYAAYCARMGNGARAARTCNATHCARCAYTGYATHMGNYTNGTNGGNGAY GAYGTNMGNAARYTNAAYGAYAARMGNCARCARGAYCCNGAYAAYYTNACNGTNATGAAR TCNYTNMGNMGNGARCARACNAARYTNMGNYTNATGCARCARGARATGAAYATHGARGAR GTNGTNAARGAYMGNACNYTNAARGTN------------ATGGTNMGNTCNYTNMGNYTN TGYGTNYTNGCNGGNYTNTGYCAY------------GAYYTNGGNCAYGGNCCNCAYTCN CAYATGTTYGAYGGNAARTTYATGCCNGTNGARGARGCNATG---AAYTGGACNCAYGAR CARGCNTCNYTNACNATGTTYGAYTAYATGATHGARGTNAAYGGNYTNATGAARTCNATH GGNGCNYTNCAYAARAAYGGNYTNMGNGARAARGAYATHAARTTYATHAARGARYTNTTY TTYGGNCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNAARCAYTTYGARATHCCNGAYCAYYTNGAYYTNGGNAAY CAYCAYACNTTYGARGTNAARGAYYTNGARAAYYTNATHAARAARACNACNGCNGAYYTN GAYAARYTNGARGARCARMGNAARACNGARTTYAARGARTAYGARATGGARAARAARTTY GARCARGCNGARCAYYTNAARGARYTNAGYGARGARGAYAARAARAARGARYTNGARMGN ATGCARGARAARCARAARAARCAYAARGAYCAYGARAARGTNAAYCAYCCNGGNAGYAAR GAYCARTTYGARGARGTNTGGGARAARGAYGAYGAYYTNAARGAYCARGARTTYGAYCCN MGNACNTTYTTYTTYAGYCAYGAYATHAAYGGNGAYATGTTYTGGGAYGARCARGARGTN GARGCNGTNYTNCARMGNGARYTNGAYAARGTNTAYGAYTCNAARGAY---CCNGARGAR GAYGAYCCNATHGARMGNGARGARGARATGMGNMGNATGMGNACNCAYATHTTYTCNGAR ATGGAYGCNGAYAARAAYAARATHATHTCNTAYGAYGARTTYATGGCNAARACNGGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGGTNGCNTTYGGNYTNCAYYTNGGNGCNTGY TCNGCNTGYGTNGCNGTNTAYAARGAYGGNAARACNGARGTNATHGCNAAYGAYYTNGGN GAYMGNGTNACNCCNGCNGTNGTNGCNTTYACNGAYCAYGAYATHGCNGTNGGNGCNGGN GCNAARCARGGNGCNATHMGNAAYCCNACNAAYACNGTNATGCAYGTNAARCAYATHATH GGNTGYGARGGNGARGARGCNGARGTNCARGARTAYATHCARAARCAYCARGTNAAYGTN AGYTTYTCNAAYAARGCNGCNGTNTTYAAYGTNGARTAYCARGGNAARAARACNCARTTY ACNTCNGAYAARATHYTNGCNATGATHTAYGGNAARATGYTNGARACNGCNCARAGYCAY AGYGGNAGYGGNATHAARGAYGCNGTNATHGCNGTNCCNTCNGAYTTYACNTCNAAYCAR MGNGAYGTNYTNAGYGAYGCNGCNACNAARGCNGGNTTYAARGTNYTNMGNGTNATHAAY GARCCNTCNTCNGCNATGYTNGCNTTYGAYGTNGGNCARTTYGAYGARACNGARCAR--- TTYAARGTNYTNGTNTAYMGNTTYGGNGGNACNTCNCAYGAYGCNACNGTNGTNAGYGTN GAYCAYGGNATGTTYTGYATHGARAAYMGNTGYGCNGAYAAYCANTTYGGNGCNGAYAAR YTNACNGARGTNYTNCARAAYTTYYTNGCNACNGARTTYAAYMGNCARTTYMGNTGYGAY GTNMGNGARAGYAARMGNTCNYTNGGNAARYTNYTNYTNGCNGCNGARMGNTGYAARCAY TCNYTNACNACNYTNCCNAAYGCNCARTGYAGYGTNGAYTCNYTNTAYGAYGGNATGGAY TTYTCNTAYAAYATGTCNMGNGCNMGNTTYGAYATGYTNGCNACNCCNYTNYTNTCNCAR TGYACNCARYTNGTNCARCARGTNYTNGAYAGYTCNGGNTAYACNAARGARGAYGTNTCN AARGTNATHYTNTGYGGNGGNGGNGCNAARTCNACNATHGTNAARAARATHATGGCNGAY TTYYTNCCNTCNGCNACNATGYTNAAYTCNATHTCNGARGAYGARATHATHGCNATHGGN GCNGCNAARGARGCNGCNYTNATGGARGGNTTYGARGAYGAYAARCARAARATHYTNGAR GARAARAGYTTYACNTTYMGNTCNYTNTCNAARGCNATHGCNGTNMGNGTNAAYTCNCCN GARYTNCARGTNGTNYTNCCNCARMGNTGYYTNATHCCNGCNMGNMGNCARCAYACNYTN ACNYTNCCNTCNGCNCARACNAGYGTNAARYTNGARATHGTNCARGTNGAYGARAGYGCN GGNGAYTCNCAR---GARCARYTNYTNGCNAARATHATHYTNMGNGAYYTNCCNCCNGGN TCNAGYATHAARTCNAGYTTYCAYYTNACNMGNCCNACNCCNCAYTCNTTYCCNGAYTCN TTYAGYGTNTCNTTYACNGARGTN---------------------ATHCAYTTYTAYAAR YTNATHAGYACNAAYAAYGGNACNTGGTAYTAYGAYTTYCCNAAYAARMGNGCNMGNTAY GAYCAYGAYGARGGNCARACNAAYAAYTTYTGYGAYGGNCARAAYYTNAGY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNATHCARATHGGNCCNGGNGGNGAYGCNGAYATHGARGGNAGYTCNGTNNNN TCNGCNTCNCCNAARAARGTNMGNTTYGARGAYAGYGTNATGACNAAYGCNTAYATHMGN CCNCCNATGCARGAYTCNACNATHTGGACNGGNCARCCNGAYTAYGAYMGNTTYYTNTAY ATHMGNATHTTYTGYCCNGARGGNYTNGARCARATHGGNACNGGNATHAARTGYTCNYTN TCNTAYGAYGGNAAYATGYTNAARACNCCNATHYTNGAYAAYCCNGARGARGAR------ GARATHGARGARCCNGARCCNATHGAYGARMGNCCNACNCARMGNCCNCARGCNGCNMGN AARTCNGAYGAYMGNGCNAAYATHGAYYTNTCN------ACNGAYTCNGCNAARAGYAAR ACNAARMGNTAYTTYGARTTYGAYATHCCNYTNCCNGAYGARATGACNGARGGNATHYTN CARYTNGGNGARMGNCCNGCNCCNGARCCNGAYAAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYCCNAGYGAYCARAAYGCNGTNGTNAAYACNTTY TAYYTNACNAGYMGNAGYGAYTGYGAYGCNGGNYTNAARCARATHTAYGAYAAYGARGCN ATHATHCARGGNTTYGAYATHTCNGARACNACNCCNGGNCCNMGNTCNTGYACNATHACN ATHTCNTCNGCNTCNATHTAYCCNGGNGTNCARYTNAARATHACNATHATHAGYATGAAY ATHMGNGAYTGYACNACNTCNYTNTCNGTNTAYGAYGGNCARGGNACNCARAARYTNGGN GCNTTYGAYTGYMGNAGYAGYACNGARATHAAYMGNATGCAYYTNGTNACNAGYGGNGAY ACNGTNACNTTYATHATGAGYMGNGAYAAYCCNGARAAYMGNCAYTTYGAYATHGARATH MGNGTNAAYCCNATHMGNGGNGGNATHAAYCCNGAYTAYGAYAARAAY------AAYTTY TTYAGYTTYCARAARTTYGAYCARGAYGCNATHGTNGGNATGATHGGNGGNYTNTAYGGN YTNGTNATHGTNATHTGYYTNGGNYTNACNTTYTAYTTYYTNACNMGNTAYMGNGGNATG AAYAARAARTGGGARACNCAYCARYTNGCNACNATGAARACNGAYACNGCNTTYGARATG MGNAGYCARGCNTCNCARCCNCCNTTYTCN------------GTNGTNGGNCARCARGGN GCNACNAGYCARTAYTCNMGNTCNTAYACNGAYCCNTAYTCNMGNAARGGNGCNGGNGCN MGNAGYGARGAYGGN---TCNAGYGTNTAYGAYCAYGAYACNAARTTYTCNCARMGNAAY YTNATGAAYGAYGARMGNGAYMGNMGNMGNGAYMGNGAYMGNATHGCNTCNCARAAYACN ACNTAYGAYGAYGAYGARGARGAYCCNAAYAAYTTYAARGARAARGTNATHACNCCNMGN TGGAARCCNGARAARTCNMGNAAYMGNMGNCCNCCNTCNTTYGARGARGCNACNMGNGAR MGNTCNTCNGARGARGARTCNGAYGAYACNGARACNGARGAYGARTCNAGYGAYGAYTCN ACNMGNAARMGNYTNACNACNTCNAGYGAYTAYAGYGARACNGCNTCN------------ ---------------------GARTCNACNCARTCNGAYAAYAGYAGYAAYMGNGCNACN GGNGCNMGNGCN---MGNMGNAAYAARAARAGYAARAARAARCCNTCNAARGCNMGNMGN MGNMGNCARAAYTCNTCNGAYGAYGCNTCNTCNCARMGNACNGARMGNACNGARCCNMGN MGNAARCCNCAYCCNCCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARAAYTCNCCNCCNATHAARATHTCNAARACNGARAAYACNYTNCARTCNGARTAY CCNAARTGYGTNGGNGARYTNGTNCAYGCNYTNCCNCAYGTNCCNYTNGCNTCNTTYGTN GARTGGTTYATHGARACNTCNTAYCCNGGNCARTTYGTNGGNTAYGAYCAYTCNGCNTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GGNMGNTTYTTYATGGCNTCNATHGAY CAYAGYATHTGGTTYCAYCAYCCNATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNCARGAYATGTCNCARGARTCNGAYAGYTCNTCN GARTCNTCNGGNGAY---AAYYTNCCNYTNYTNATHGGNYTNCCNACNTGYGCNYTNYTN ATHATHATHYTNATHATHGTNTTYYTNYTNCARMGNAGYAAYGGNTGYAARMGNTCNACN ACNAAYACNAARGTNCCNMGNACNCCNGTNCCNCCNGCNGARMGNGARGCNCAYTAYTAY AGYAAYTGYCARCARCARCAYATGCARCARTCNGTNAAYCCNYTNYTNYTNTCNMGNGAY AARYTNCCNAARACNCCNACNCCNTCNGTNGAYATG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYATH TGYMGNYTNGCNMGNMGNCARAARMGNYTNTGYGAYGAYCCNACNATHCAYMGNCAYGTN GARCAYTTYATGAAYGARCARATHGAYCAYYTNCAYTGYACNTGYACNTCNYTNTAYGAR GAYYTNMGNCAYGGNCAYGAYGAYYTNTCNACNACNGCNYTNATHGGNATHGGNGCNGGN GCNATHYTNTTYYTNTGYATHTTYTTYGGNGTNYTNTTYTGYTGYTGGMGNMGNAARMGN AAYAARAARAARMGNMGNAARGGNCCNAAYGTNATHTAYYTNCCNGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGYTNGAYGARGGNAGYGGNGTNATGGAR AARAARAGYTGYMGNCAR------CCNGCNTCNACNCARTGYMGNAAY---GGNGCNAAY GGNGARAARAARTCNGAYTTYGTNCCNAAYAARMGNGGNTTYGGNMGNMGNCARGGNACN YTNGCNACNGGNAARGTNTCNGAYGGNCARGCNCCNMGNCCNGTN------CCNATHCAR AARTGGGAYMGNCCNATGGGNGAYMGNMGNCARMGNCARMGNATHGGNTAYGAYTAYMGN CARMGNGARGARGTNGTNGARAGYGGNGAYGGNGTNGAYGTNYTNACNACNGGNTCNMGN AARGGNAAYGCNAAYCAYYTNYTNAAYTTYCAYTAYGAYGAYCAY--------------- ---------MGNTGGTGYAARTCNMGNGGNGGNGTNGGN---------------TCNMGN AARGCNAARMGNTAYAARAARGARCARTTYYTNCARGCNTGYTGYCARTTYGTNGTNMGN GAYTCNGGNGAYTAYACNGARCARACNATHAAYTGYGAYACNYTNGTNGAYTGGAAYATG ATHGARYTNGTNMGNAGYTTYTCNGTNGARCCNGTNCAYTGYCCNATHTGYYTNCARTAY CCNATHGCNGGNAARATHACNAARTGYGGNCAYACNTAYTGYTGGGCNTGYATHYTNCAY TAYATHAARYTNGGNCARGAYGARGCNMGNAARTGYCCNATHTGYTAYGARAAYGTNGAR ATHGAYGARYTNMGNAGYGTNMGNTGGATHGAYGTNCCNAGYTTYAARGTNGGNGAYGAR ATHACNATGAARYTNATGMGNAARACNAARGGNAGYGTNATHGCNYTNCCNAARGARCAR TGGAARGAYATGCARGGNAARCAYATGAAYATHGARGGNGGNCCNAAYACNAARTAYATG AARYTNYTNGTNGCNTCNYTNCARCARATHAARAARGARGTNATHTGGGARGARMGNAAY GARYTNACNGCNCARYTNYTNGAYGCNGARGARTCNGARGTNTGYTTYATHCARATGGCN YTNGAYGAYYTNGCNGARMGNGARACNAAYYTNAARACNGGNATGCAYAAYGCNGTNTAY ATHCCNTCNGTNGARGCNTGYAARCCNGAYCARGTNGCNGTNAGYACNGARAARGAYATH ACNAAYTCNGTN---------------------ATHACNACNTAYGCNGAYGCNTTYGAR GGN--------------------------------------------------------- ---------------------------GARGTNYTNAAYACNTCNGAYACNACNGARAAY GGNGTNGTNGARGAY---GCNTCNYTN---------GCNATHGAY--------------- ------------------------------------------------------------ ---------ATHTCNAAYMGNCARMGNATHGAYAGYGARAAYTCNYTNCCNTTYGGNTCN CCNCCNTGYCCNTTYCCNYTNATHCCNGAYCARGARGTNAAYCCNGTNCCNYTNAGYYTN GARGARACNTCNGAYCAYYTNGARYTNCCN------ATGAAYCARTCNCCNCARAGYTCN MGNAAYGTNCCNYTNYTNAAYACNTCNGAYACNTAYTAYTTYTAYCARGCNTCNACNGGN CARCAYATHTAYATGAAYTCNYTNAAYGCNCARTGYYTNGCNAARGARTAYGGNTCNYTN GARGAYAGYCCNGAYYTNATHAAYGCNTCNATHGTNGCNATHGARMGNATHTTYATGACN GARGAYGTNMGNAARMGNYTNMGNTAYYTNGAYCAYATHCCNYTNACNAGYGARGTNCAY GTNGTNGARYTNAAYATHAARCCNCCNACNATHAGYAARGARACNYTNAARTTYTAYGAR GGNGCNYTNAAYAARAARMGNAARCARMGNCARCARAARGARAARGARGAYAARMGNMGN GCNAARAARTTYGARATHGARCAYAARAARAGYTTYGGNATHTAYCCNGARGTNCARYTN CCNYTNGAYAAYGTNTAYCARTTYCCNGCNCCNYTN------------------------ ---GTNCARGARTGGYTNAARGCNTCNTAYAAYATHAAYATHTCNGARGAYTGGYTNTCN TCNTGYATHGARTTYATHCARCARGARTCNCARACNMGN---YTNGAYYTNAARGAYATG AARMGNCAYGTNTTYGAYCARTGGYTNATGTCNGAYYTNACNGARATHGGNAAYCCNGTN ATHCCNGAYGARGTNTTYTCNGGNGAYAARCAYGTNYTNCCNGCNATHTAYCCNYTNCAR ATGATHTCNATHGTNGAYGTNGCNAGYCCNTTYTAYGGNCARYTNCARAARTTYGARACN AAYGGNYTNACNTCNGAYYTNATHACNTTYTCNGAYACNTCNTTYAAYAAYAAYTAYAGY AAY------------------AARTCNTCNMGNATGYTNAARYTNGARYTNTCNGAYGGN CARMGNAAYYTNCARGCNATHGARTAYACNCCNATHMGNGCNYTNAAYAARGAYYTNTCN TCNGGNACNAARATHYTNATHAARGGNCCNGTNGTNTGYMGNMGNCARATGYTNYTNYTN CARGARGARAAYGTNTGYYTNATGGGNGGNGARGTNGAYGAYYTNATHGTNGTNAAYAAY CCNYTNATGAAYYTNCARTCNGARYTNGARMGNAAYMGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYAAR GTNGTNYTNTAYAGYTAYTTYMGNAGYTCNGCNAGYTGGMGNGTNMGNATHGGNYTNGCN YTNAARAAYGTNGCNTAYGARTAYGARCCNGTNCAYYTNGTNAARGGNCARCARCAYACN GARGARAAYAARAARYTNAAYCCNATGGGNGCNATHCCNACNYTNAARATHAAYGGNCAY GTNYTNCAYCARTCNYTNCCNATHYTNGARTAYYTNGAYGARATHTTYCCNGAYAAYCCN YTNYTNCCNAARGAYCCNGCNGCNAARGCNCARGTNMGNGCNATHGCNGARATHGTNAAY AGYGGNATGCARCCNYTNCARAAYYTNAARGTNYTNYTNAARGTNGGNGARACNAARATH GARTGGGCNAAYCAYTTYYTNACNCARGGNTTYCAYGCNYTNGARTCNATHYTNAARAAR ACNGCNGGNACNTGYTGYTAYGGNGAYCARGTNACNYTNGCNGAYATHTGYYTNGTNCCN CARGTNGCNAGYGGN---CCNMGNTTYAAYGTNGAYATGAGYCARTTYCCNACNGTNGAR AARGTNAAYAARCAYYTNGTNGARYTNCCNGCNTTYAARGCNGCNGAYTCNMGNMGNCAR CCNGAYACNCCNGARGAYATGMGNATHGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATGCAYTCNCCNGGNTCNCAYGCNGCNCAYTGYYTNCCN GTNGCNGGNYTNMGNCCNCCNGTNGAYATHGAYGTNTAYMGNCAYAAYMGNGTNGTNCCN GTNTAYACNCCNGAYCCNTGYATHGGNCCNAAYTCNACNCARYTNYTNTGYCCNCCNGAY TGYGGNCARTCNAARMGNAAYGAYYTNATGGARCCNGCNGGNATGAARACNCCNATHGAR ATGCARTTYCARTTYTAYCARCCNMGNCCNTCNMGNCCNGARCCNAARYTNGCNTGYAAY TGYCCNGCNTTYGCNAAYMGNCARCCNTGYAAYATGYTNGGNCCNGTNACNGAYMGNYTN AAYTGYCCNTGYATHAAYATGTCNGAYAARYTNTCNACNAARGTNATHCARGTNACNAAY ATHGCNCCNAGYTGYACNAARGARCARYTNMGNACNYTNTTYGGNTAYYTNGGNMGNATH MGNGAYYTNGCNATGTAYCCNCCNGARGGNGCNGAYACNTCN---TCNACNTCNMGNGTN TCNTAYATHGARTTYGARGAYTCNCARACNACNGGNGTNGCNYTNCAYYTNAGYAGYACN GTNTTYATHGAYMGNGCNATHYTNGTNGTNCCNGTNATGGAYGGNAARATHCCNGARGAR AGYGCNGCNYTNCARYTNACNCCNTCNGCNGTNGCNGGNATGYTNCCNGGNCARCCNACN TGGCCNGCNAAYGTNGTNTCNCARGTNACNGGNYTNGGNGCNAAYCARGTNATHATGACN AAYGAYCCNMGNYTNACNTCNYTNGGNYTNCCNCARTAYCCNCCNYTNCCNGCNACNACN GAYCCNAGYAARATHGARGARATHMGNMGNACNGTNTAYGTNTCNGARYTNGAYGCNAAR GTNTCNCCNGARATGYTNYTNTCNTTYTTYTCNCARACNGGNGARATHAARTAYATHMGN ATGGCNGGNGAYGARAAYGCNCCNACNMGNAGYGCNTAYATHGARTTYACNGAYCARMGN TGYATHGCNCARGCNYTNAGYTAYAAYAAYATHGTNTTYCARGGNMGNACNGTNAGYGTN AARCAYGCNACNACNAGYATHGTNAARCCNACNCCNAARTCNGARGCNTCNCARMGNGAR ATHGAYGAYGCNATGAARAARGTNAARGARGCNTCNAARYTNATHTCNGCNGCNGCNAAY AGYGARMGNGARGGNTCNMGNTCNCCNAGYMGNAAR------MGNTCNAARTCNMGNGGN MGNAGYMGNTCNCAYTCNAARTCNMGNAARTCNMGNTCNMGNTCNMGN---GGNMGNMGN MGNMGNAGYATHTCNMGNACNMGNMGNMGNTCNMGNTCNMGNMGNMGNTCNCCNMGNMGN TCNMGNACNCCNGTNMGNMGNMGNMGNTCNMGNTCNMGNGGNCARGARGCNCCNCCNGCN CCNCCNYTN------------------TCNMGNMGNMGNTCNAARACNMGNTCNCCNATH MGNAARMGNMGNTCNMGNAGYMGNTCNAARTCNAARCCNMGNMGNTCNMGNACNCCNCCN AARTCNTAYAGYMGNGGNMGNMGNTCNMGNTCNMGNGGNMGNAARAGYMGNTCNMGNGAY MGNAARGARMGNAARGARAARAARAARAGYMGNTCNCCNTCNCCNCCNACNYTNGTNMGN GARGCNACNGTNGCNGAYGAYGGNGAYAARTCNCCNGTNAARGCNAAY------GCNMGN TCNCCNAGYCCNGCNAARATHAARAARMGNAGYCCNTCNYTNAARMGNMGNAGYMGNTCN AARTCNCCNAGYAAYMGNMGNAARAARMGNCAYMGNTCNMGNTCNACNTCN---MGNAAR MGNTCNMGNTCNMGNAGYGGNTCNMGNCAYMGNGTNMGNMGNGAYMGNMGNMGNAGYMGN AGYCAYGAY---------ATH---ATHMGNAARAARACNAGYMGNGAYAARGAYGAYMGN MGNMGNGAY------TCNAGYTCNAARATHAARMGNGAYTAYGAYGARGARGARAARGGN TTYACNAGYGAYMGNAGYGAYGAYAARGAYAAYAGYGARGCNGARGGNGTNAARGTNYTN GAYTCN------CCNGTNAAYCAYTCNYTNGARAARGAYACNGAYCAYCARTCNGTNGAY ATGGAYATGAGYGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TAYGGNAARATHGCNCARAARYTNYTNAARATHGCNGAY TCNTAYAGYYTNGAYATGTCNGAYTCNGARGCNMGNGGNATHGARGAY---------GCN CCNYTNACNGAYYTNGARAARGARATHATHGCNTGYYTNMGNTCNGGNGGNGAYAARTAY GGNAARAARATGGARGAYCARYTNGAYGCNYTNAARTCNGCNGTNGCNGARGAYACNTAY GGNMGNTTYMGNAGYACNGTNCARAAYTCNATGGGNCAYGARYTNAGYTGGAAYACNYTN GCNYTNYTNTTYTAYGCNACNAARGGNGTNGTNTCNGCNGTNGGNAARAGYTCNCARGTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------MGNATG AARYTNCARCAYGARCARGCNAARYTNYTNGAYTAYTCNYTNCARGTNTGYYTNGGNATG GARTAYYTNAAYAARAARCARATHATHCAYMGNGAYYTNGCNGCNMGNAAYTGYYTNGTN GGNAARAAYGARGTNGTNAARGTNGGNGAYTTYGGNYTNGCNMGNGARGTNYTNCCNGAY TTYGARTAYCARATGTCNGARYTNTCNAARTTYCCNTTYAARTGGTCNCCNCCNGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CAYYTNTGYATGTTYAGYCCNCCN CARMGNGGNTCNYTNGTNGGNATHAAYAARCCNGCNGCNGCNGAYTGYATGYTNGTNGCN GGNCCNTGYGGNGGNMGNTCNAARTCNMGNACNGTNYTNGARATHCCNGGNGGNTCNACN TTYACNGTNGCNTTYCARAARAAYYTNGAYCAYTTYAAYAARAAYAARCCNGGNCARTTY GTNGTNTCNATHGGNCCNAAYACNGAYTCNATGATHAARYTNGAYACNATHCCNGAYACN GAYACNCCNTCNYTNACNGTNTAYGCNGTNAAYGTNACNATHCCNGCNAARATHGGNGAY ATGGTNYTNCARAGYCARTAYATHACNTCNAAYCCNAARGCNCCNCCNAGYTTYTAYCAR TGYGCNGAYYTNMGNATHGTNCCN------GCNMGNTAYMGNGTNYTNCARYTNCARATH YTNYTNCCNTTYYTNTGYYTNYTNYTNMGNCARTAYGAYYTNCCNGARATHACNGTNGAY TTYATHMGNAARTTYGGNCAYGTNGAYCAYCAYATHGARCARYTNACNGAYGAYGCNATH GCNAGYATGAAYGARACNGARYTNATHGTNACNGTNCAYAGYTAYYTNGAYAAYGCNGAY ATHYTNTGYMGNMGNAARYTNMGNATGGGNCARGTNGGNGAYGGNGGNTGGGARATHTGY GAYGAYCARGAYATHMGNCCNCARGTNCCNTTYTGYACNGTNTAYTCNTTYAGYTTYGTN GCNGAYTAYGCNTTYGARGAYGAYATHTCNMGNATHTAYAAYTGYGARGTNCAYTCNTTY AAYCCNAAYYTNCCNGGNCCNGAYTAYAAYMGNTCNTCNAARGTNTAYGTNCAYCCNTAY GGNGCNGGNMGNAAYACNGARATHACNCCNAAYGGNAARGARYTNTAYACNYTNGARGAY ATHCARACNATHYTNGGNCAYAGYGAYAARAGYATHGAYATHATHAARATGGAYATHGAR AGYACNGARTGGAAYGCNYTNACNCAYATGGCNTCNTCNAARCARYTNAARAARGTNMGN CARYTNYTNGTNGARTTYCAYATHGGNTAYCCNCCNAAYATHTAYAARYTNACNMGNGCN GTNMGNGTNYTNMGNTCNYTNAGYGTNYTNGGNTTYMGNAARTTYTAYGTNCAYAARAAY CCNAARGGNTCNTTYCAYCAYCCNGGNTTYCCNGTNATHMGNGCNMGNAAYTAYGARGTN CAYTAYATHAAYTCNAAYTTYATH------------------------------------ ---------------------TGGGTNMGNYTNAARMGNMGNGARTCNYTNGGNYTNGCN GAYTAYATHAGYGGNMGNGCNCCNCARAGYCCNAAYACNGTNAARYTNGCNCCNGTNGAR TCNTCNGGNYTNCAYGCNGCNCCNAGYTTYMGNAGYAAYTCNYTNATHGTNACNACNGAR GCN---MGNGGNAARATGGTNGAYACNCARACNGTNGTNTCNGCNYTNMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARATHTCNCAY ATGATHGCNTTYATHGAYCARGARGCNTCNGARAARGTNGARGARATHGAYYTNAARGCN GARGARGARTTYAAYATHGARAARGGNMGNYTNGTNCARCARTCNMGNGTNCARATHATH GAYTTYTAYGAYAARAARATHAARAAYGTNGARYTNCARAARAARATHCARAAYTCNAAY ATGCARAAYAAYGCNMGNYTNGARGTNYTNMGNAARAARGARGAYTAYGTNAARGARGTN YTNAAYGAYGCNMGNGARCARYTNAARAARAGYGCNMGNGAYGAYCCNGARGARTAYAAR CAYYTNYTNYTNYTNYTNATHTCNCARGCNYTNGCNMGNYTNGTNGARCARGARGTNACN ATHMGNTGYAARCARGARGAYGTNCARATGATHAARAAYGCNATHCCNGCNYTNACNAAR GARTAYCARGARGTNATGAARGGNAARTAYACNGTNAARYTNAARGTNGAYGARGAYAAR TTYYTNTCNTCNGARATHACNGGNGGNGTNGARYTNCAYGCNATGAAYGGNAARATHGTN GTNGTNAAYACNYTNGAYGARMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHCCNCARATGYTNTTYYTNAAYCARGTNACNATHAAYGGNCARACN TCNTTYGTNYTNGTNGAYGTNGAYAAYAARCCNATHCARYTNCCNCARGGNATHCARGTN ATHAAYYTNCCNCAYCARCARYTNTCNGGNCARTCNGTNCARATGCCNGGNGCNGAYACN GGNGAYGARCCNYTNTAYGTNAAYGCNAARCARTAYCAYMGNATHYTNAARMGNMGNCAR GCNMGNGCNAARYTNGARTCNGARGGNAARATHCCNAARGARMGNCARAARTAYYTNTAY GARTCNMGNCAYMGNCAYGCNYTNAAYMGNGCNMGNGGNACNGGNGGNATHTTYGTNGGN CAR------TCNYTNGAYGTNGTNYTNGTNTTYGGNAARAAYAARATHYTNGTNACNGTN CARTCNCCNCARGGNGAYGCNMGNGAYAAYYTNYTNACNGTNAAYGAYYTNTGYMGNATG ATHGARGARCAYACNAAYATHCARCCNAAYGCNCARAARYTNATHTAYMGNGGNMGNACN YTNTTYAARAARTAYGAYCCNGAYGAYGAYGCNYTNCARAARAGYYTNCAYTCNATHGGN ATHAARAAYGGNGARMGNATHATGGTNTTYGGNAARGTNTCNAGYGAYGARMGNGARAAY GGNAGYAAYGAYGCNGARGTNGCNYTNATG------AARYTNYTNGAYCARCAYCARGCN AARATHGAYGARATHTGYAAYYTNTGYGCNGAYATGATHAGYAARATHMGNAAYCCNGGN ACN---ATHGARGAYTGGAARAARTAYAARAARTTYTTYYTNGGNCARTCNGARTAYTCN ATGCARGARYTNACNMGNYTNGAYGCNACNCCNGGNGAYYTNTCNCARMGNCAYGARTAY AARACNMGNMGNAARGCNYTNGTNAAYCARYTNYTNGARAAYGTNTCNYTNTGYGAYAAY CARGTNGGNAARTGGACNGARTCNATHCARAARTAYGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TCNMGN AAYGGNACNATGTCNTTYAAYTTYCAYATHCCNGGNAARGAYGGNMGNGARTCNGAYCAR CCNGCNYTNAARTTYAAYGCNAAYGARACNYTNTTYGARTTYACNYTNAAYAAYTAYACN CCNATGTAYAAYAAYACNMGNTTYGGNYTNCARGCNATGGTNGTNACNCARGGNGGNAAY TCNAARATGTCNGTNGARACNAGYMGNACNATHGAYGAYGARTAYTCNCCNGGNGTNTTY CARGTNACNAAYTGGATGACNMGNGARGAYCAYCARAGYCARTCNGGNTTYATGCARTGG AARCCNGTNGCNTAYTTYGGNAARCCNMGNGGNMGNCARACNTCNACNAARGTNAARCAY TAYGAYYTNGARACNGGNGAYGAYGTNMGNATGYTNAAYYTNACNYTNGTNTCNGCNYTN TTYGAYGARTCNYTNTAYGAYGGNACNTCNACNATHMGNAARATG---AAYATHACNTTY GGNCARCCNAARGAYGGNTTYTAYAAYGARAAYAAYTTYACNGTNTGGAAYGGNGCNATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHAARGTNYTNGARTTYGTNYTNGCNATHTTYGCNTTYGCN ACNACNACNAGYCCNGAYACNTCNACNACNATHACNGTNAARAAYTGYAGYGCNACNACN AAYAAYACNAAYAARGAYCCNGCNTCNTAYACNTAYTCNTAYAGYTAYCCNTTYGAYYTN GARAGYGTNTGYYTNCCNGTNCCNYTNTGYGCNCARAGYYTNCCNAAR---------TCN ACNTTYTGYYTNYTNGARGGNTCNCARTCNGCNGCNCARTTYTAYGTNTTYATHGGNGTN ATHGTNTTYYTNTAYTGYYTNGGNGCNATHATHYTNTAYGTNTTYTTYGAYGARYTNTAY MGNMGNAAYACNMGNGTNGTNYTNGCNGAYTTYYTNATHTCNTGYGGNYTNACNYTNYTN TGGATHATHGCNTCNTCNGCNTGGGCNTCNGGNYTNAGYGAYGTNAARYTNTAYACNGAY CCNACNGAYGGNGARGTNTTY---ATGAAYATHCCNGARTGY---AAYGCNAARGGNGCN TGYTAYATGGCNAARGARGGNAAYTTYGCNAGYYTNAAYGTNTCNATHATHTTYGGNTTY YTNAAYTTYGTNGTNTGGGTNGGNAAYYTNTGGTTYYTNTAYAARGARACNCCNTGGTTY AARGTNCARGCNAARCCNCCNACNGAYCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CCNMGNTGYGTNACNGAYYTNCCNCARCCNTTYGAYTTYCAYTGGTCNTCN TCN------YTNAAYGAYGTNGTNATHCARTTYGARGCNGTNYTNGARYTNTAYCARGAR TTYTGGAAYATGYTNGAYGARATHGAYAARAAYACNTGGGTNYTNGARCCNGARTCNCCN AGYTTYTCNTGYACNCAYMGNMGNATHGCNATHGGNCARAAYYTNTCNYTNCAYATHGTN ATHAAYCARYTNCARCCNTCNACNYTNCCNGARTGYMGNTTYYTNGGNGCNGARTTYGCN GTNGCNCCNYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYTCNGAYAAYAGYAAYGAYGGNMGNCAYCARCAYCCNTCNCAY ATGTCNGARMGNCCNMGNCAYCAYMGNMGNCARCAYTAYGAYTCNTAYAAYCAYGAYATG GGNMGNMGNGAYMGNGAYTCNTTYGGNGCNGGNGCNCCNGAYYTNGCNCARCARACNTCN GGNYTNGAYGCNGCNAARMGNMGNGCNYTNCCNYTNTGGYTNMGNGARGGNYTNGARAAR ATGGARAARGAYAARCARAARCARYTNGAYAARGARCARYTNAARAARCARCARGARACN AARAAYAARGAYGTNAARGARGARGARGARGARGARGAYGAYGGNCARCCN--------- ------------AARGTNCCNMGNAARAGYMGNTTYGAYTCNGAYGAYGARGAY------ ---GARGTNAARGARGAYGARGTNAARGARGGNGGNGAYAAYGAYGTNGGNGAYACNACN CARCCNCCNAARCCNGARYTNTCNTCNACNAARGARTCNCCNGTN------------MGN AARAGYCCNTCNCCNACNCARTTYATGACNGARGARGARAARGARGTNGCNYTNATGATG AARGTNAARMGNYTNYTNACNGARACNYTNYTNGAYGTNACNGAYMGNGARYTNAARAGY ATHGCNAARGARGTNTAYGARAARGARAARAARAARGCNCARAARGCNCCNGCNAARCAR YTNGCNAARTCNTCNGCNYTNGCNTCNYTNTCNACNYTNGGNYTNGGNTAYGGNTCNGGN AGYGAY---------------------AGYGAYCARGARCARGAYTCNGAYTCNGAYYTN GARGARMGNATHMGNCARAARAARGCNGAYTTYGCNAARMGNCARAAYATHTTYAGYGAR TCNGARGAYGAYGGNGARAARACNTCN---------CCNAGYAARMGNMGNAGYGARGAR GAYAARCAYAGYAGYAARMGNGTNAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTAYAAYGGNATHGGNYTNCARACN CCNMGNGGNAGYGGNACNAAYGGNTAYGTNCARMGNAAYYTNGCNTTYGTNAARGGNAAR AARGAYMGNGTNGAYTAYAARAAYGARGAYGARYTNAARAARYTNGARCARTCNYTNCAY AARCCNCCNAAYCARGARATHYTNGAYCAYGARMGNAARMGNAARGTNGARYTNAARTGY ATGGARATGCARGARYTNATGGARGARCARGGNTAYACNAGYAARGARGTNGTNGAYAAR GTNAAYATGTTYMGNAARATGYTNATGGCNAARGARGGNGTNTCNGAYACNTCN---ATH GARAARGAYGARCAYGGNMGNCCNATHGCNAARGARACNCAYCARYTNGCNGARGCNAAY CARGTNAARAAYGAYMGNYTNAARGARGCNTTYGGNYTNTCNGAYTAYGTNGARGGNAGY GCNTTYGAYCCNGAYMGNAARGCNAARGARGARCARGCNAARGCNYTNGCNYTNGCNCAR AARAARTAYAGYATHGTNAAYAGYTCNGAYGARGAYAAR---------GARAGYTCNCCN ACNCCNAARAARAARAARAARAARTCNMGNCAYGARGAYGCNTCNTCNCCNGARMGNAGY AARGARAARMGNAARAARAGYMGNAARCAYAGYAARMGNGAYMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GCNGAYYTNAGYACNYTNMGNCARCARATHGGNGAYGAYAGYYTNGGN AAYCCNAAYACN---GAYAARCAYGARCAYGGNAARGCNGCNAARTAYGTNGCNATGGAY AARTTYGARAARGTNTGYYTNGARYTNTCNGGNGCNYTNMGNMGNGARCARAARGCNCAR YTNYTNYTNCARGARCARAGYAAYCARYTNGCNGARYTNACNACNMGNYTNGAYYTNTGY GCNTCNGAYGGNGTNAAYAARGARCARAGYYTNGTNAAYATHCARGARGGNYTNTCNGAR ATGCARGGNCAYYTNMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNATHAARACNACNACN ACNGARAAYCCNTTYCARGARGCNGAYTTYATHCAYGAYCAYCAYGTNTAYTAYAAYTCN AGYGCNGARAARGARAARAAYGARACNCAYTAY---GTNGAYYTNTCNTCNGGNTCNMGN CAYGARATHYTNTCNAAYAGYCAYMGNGTNGCNGCNATHATHAARYTNAARTTYAARTTY CCNTTYTAYGGNCAYCCNATHACNAAYGTNACNGTNGCNACNGGNGGNTTYATGTAYATG AGYCCNTTYYTNCAYCARTGGYTNACNGCNACNCARTAYATHGCNCCNYTNATGGCNAAY TTYGAYCCNTCNGTNAGYAGYGAYTCNCAYATHTAYTAYYTNGGNGARGARGARMGNTTY ACNGTNGARTGGMGNGARGTNATHYTNAARGAYCARCARGAYYTNGGNAAYTTYACNTTY CARGCNTCNYTNCAYGTNGAYGGNAGYATHAAYTTYGCNTAYAARCARATHCCNTCNGAY GTNAAYAGYATHTCNGAYGAYAAYCAYCCNGTNAARATHGGNYTNTCNGAYGCNTAYTAY AAYGAYACNTAYYTNCCNGARTGGGGNATHMGNMGNMGNACNATHTAYGARTAYCAYCAR GTNAARYTNMGNAARAGYTTYGCNCARACNGGNGCNGTNATHACNGTNAAYCCNYTNCCN ACN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AAYMGNCAYMGNTCNCCNAARACNAAYGGNYTNCCNTCN TAYTCNTAYMGNMGNGTNTCNGCNCCNCCNGGNAGYYTNYTNTAYGCNGARCCNYTNTAY GGNTGYAARTGYTCNGCNTGYGARGARGCNATGAGYAGYGAYATHCAYTCNGCNYTNAGY GCNGCNYTNAAYGARAARYTNCARAARTTYCCNATHMGNYTNGARGTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNGCNAAYAARGAYGTNAARATGTTYAAYYTNTTYTGYCCN ATGAGYGGNATHGAYTCNGARGTNTGYTAYGGNATGTTYAARYTNTTYGGNTGGCCNYTN ATHGCNGGNGGNTTYGCNCAYAARMGNATHYTNMGNGAYTCNCARGGNGARTTYCAYAAY TCNAGYGARTCNTGYYTNGTNTCNGGNYTNTCNTTYTGYGGNGAYAAYGTNCARGTNGCN TCNGTNATHYTNMGNAGYTAYATHCARMGNCCNGAYGARGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARGARGCNGARATHACNTCNTGGYTN TCNCARYTNTTYGGNAAYGARGAYATHCCNGARTAYGARAARAAYYTNCARACNTTYGAR YTNYTNCAYCARYTNGCNTCNAARAGYYTNMGNAAYGARAGYAAYATGCARYTNTAYGTN GARGAYYTNAARMGNAARGCNGAYGARTAYGAYGCNGAYGCNCAYMGNYTNGARAGYGTN YTNACNMGNYTNTCNATGGGNTCNAAYAGYTGYTCNACNACNGCNYTNTCNCAYACNMGN GCNYTNGCNCARTGYGGNGCNYTNYTNGGNGTNAARAAYGCNTCNGAYACNAGYTAYATG YTNTGYATGCARGARYTNAAYTCNGAYATGCAYGAYGTNACNGARAARATGGARGAYGAR TCNAARGCNGTNCARAAYATHTCNAARMGNGCNCARAAYATHYTNYTNAARCAYAGYACN YTNAARMGNGCNYTNAARGAYGTNGARAARAARTCNACNMGNGAYGTNGCNCARATGAAR ACNAARAARAARGARATHGARAARYTNAARGGNTCNGCNGARGARTCNGARCAYAARTCN ACNAARYTNAARACNGARYTNACNAARACNGGNYTNAGYGARTCNTAYTAYCAYGAYMGN YTNGTNAARAARAARGARAARYTNGAYAGYYTNCARGARGARYTNGTNCCNYTNCARGCN AARYTNAARTCNTAYGCNATHYTNCCNCCNAAYCCNGTNGARGCNAARGTNAARATHGCN GARYTNAARATGGARYTNGAYGTNYTNAARGCNCARATGTCNGARTGYGTN--------- ------ACNATGGARTGYGGNACNTCNTCNGTNGTNTTYGCNATHYTNYTNTCNYTNTGY ACNTCNGTNGARGCNTTYYTNGTNTTYTCNGCNGGNGTNTGYCCNGARGTNGAYGTNAAR CARGAYTTYAAYGTNTCNGCNTAYGTNGGNAARTGGTTYAGYTAYGARAAYTTYGAYGCN CCNTAYCARTTYGGNATGTCNTGYGTNACNGCNAAYTAYMGNMGNYTNCCNGAYAAYACN ATHGARGTNAARAAYGARGGNTTYAGYGCNATHMGNGTNTTYGGNATGTAYYTNAAYMGN MGNCCNATHGTNGCNYTNGGNTCNGCNMGNGTNYTNGAYTGGTCNGAYCCNGCNMGNYTN MGNGTNGGNTTYGGNCARCCNGAYTTYATHGGNGCNCCNAARCCNAAYTAYCARGTNATH GAYACNGAYTAYAARACNTAYAGYYTNGTNTAYTCNTGYAGYAGYYTN---ATHATHCCN TTYAARYTNGARGGNGCNTGGATHYTNACNMGNACNMGNGGNGCNMGNCCNGTNAAYACN AAYGARYTNAARAGYAARYTNGCNTCNTAYGGNGTNAARACNAARTAYTTYAARCCNGTN GAYCAYAAYAAYTGY--------------------------------------------- ------------------------------------------------------------ ------------------------AARAARAARAARAARAARAARAARAARTGGYTNTGY ATHTGYYTNACNAAYTGYAARTAYGAYGTNGTNMGNMGNACNTCNMGNAARTTYGGNTTY AARGARGTNCARGAYGAYGARGAYTGGACNYTNTAYTGGACNGAYTTYTCNGTNGCNYTN GARMGNGTNATGGARATGAARAAYTAYCARAARATHAAYCAYTTYCCNGGNATGAAYGAR ATHTGYMGNAARGAYATGYTNGCNMGNAAYYTNAAYMGNATGCARAARYTNTTYCCNAAR GARTAYAGYGTNTTYCCNAARACNTGGTGYYTNCCNGCNGAYTAYGGNGAYTTYCARGCN TAYACNMGNCARAARAARAAYAARACNTAYATHYTNAARCCNGGNTCNGGNTGYCARGGN MGNGGNATHTGGGTNACNAARAAYCCNAARGAYATHAARCCNCAYGARCAYATGATHTGY CARGTNTAYATHAGYAARCCNTTYYTNATHGAYGGNTTYAARTTYGAYYTNMGNATHTAY ACNYTNGTNACNTCNTGYGAYCCNYTNMGNATHTTYGTNTTYAARGAYGGNYTNGCNMGN TTYGCNACNAAYAARTAYGTNGARCCNAGYCAYAAYAAYACNGAYAAYGTNTAYATGCAY YTNACNAAYTAYGCNATHAAYAARCAYAGYGARGAYTTYATHMGNGAYGAYGARGCNGGN AGYAARMGNMGNATHAGYACNATHAAYMGNTAYYTNAAYGARAARGGNTAYGAYGTNGAR MGNATGTGGTCNGAYATHGAYGAYGTNATHATHAARACNGTNATHTCNGCNCAYTCNGTN YTNAARCAYAAYTAYMGNTCNTGYTTYCCNAAYCAYATHMGNGGNTCNGCNTGYTTYGAR ATHYTNGGNATHGAYATHYTNYTNGAYAARAARYTNAARCCNAGYATHYTNGARGTNAAY CAYTCNCCNAGYTTYACNACNGAYGCNGAYYTNGAYMGNGARATHAARGGNACNYTNGTN TAYGAYACNYTNMGNYTNATHAAYTTYGGNGCNGTNGAYMGNMGNAARTGYYTNGAYGAR GARMGNAARMGNATHAARGAYMGNYTNYTNGGNAARTAYGTNAARAARGARACNAARGAR GARYTNGARGCNGCNCARACNCARTAYATHGARCARYTNGARMGNTAYGARGAYGGNCAY YTNGGNAAYTTYMGNMGNATHTTYCCNYTNCCNGGNACNGARAARTAYGAYAARTAYTTY CAYAGYAGYGGNACNYTNTTYCARGARACNGCNGCNTTYMGNGCNMGNCARGARYTNGCN MGNCARCARMGNGARGARATHYTNMGNAARAARGARAARAAYGARATGATGYTNAARGGN AARGCNAARAARGAYGGNYTNMGNCCNGARAGYCCNGGNMGNAARMGNMGNYTNAGYCAR MGNCCNACNYTNCCNYTNMGNCAYATHACNCARMGN------GAYTCNAARGAYTGYGAR CCNGTNGAYACNACNAARCCNCARGAYATHGTNGARGAYGARGARYTNGARMGNYTNTCN GGNYTNYTNCARMGNGAYAAYYTNGTNMGNGGNYTNGGNATHGTNGARCAYGTNTAYMGN YTNYTNCAYTGYACNCCNGGNACNATGGGNGTNGTNMGNCARGAYCARMGNGCNAAYCAR GGNGGNGCNGGNCARAGYCAYACNYTN---MGNGCNMGNMGNGTNGCNGGNGGNCAYCCN CAYGAYMGNAAYGGNTGGCCNTGGYTNGCNTCNATHGARGTNMGNTGGAAYYTNACNAAY GAYGTNTCNCCNGAYTAYMGNCAYTAYTGYGGNGGNAGYYTNGTNAAYCCNCARTGGGTN YTNTCNGCNATHCAYTGY------TTYATGGGNCAYTCNCCNCCNTAYAAYAAYATGTCN AAYTGGMGNGTNGTNYTNGGNGAYTAYGAYAARAARGCNAAYGAYGGNACNGARCARCAR ATHTAYYTNGAYCAYATHMGNYTNCARCARATHTAYGAYGAYCAYGGNCARTTYGGNGCN GAYATHGTNYTNGTNCAYYTNACNGARCCNGTNAAYATHACNGAYGCNGTNCARCCNGTN GTNYTNGAYAARMGNGAYTGGYTNGGNCAYGGNCCNCARTGYCARATGGTNGGNTGG--- ------------GAYACNATHACNMGNCCN------GGNYTNGCNACNTTYGTNCCNTAY GARGTNAAYGTNMGNCARMGNMGNATHAARTGGTGYAARCARCARTTYMGNGTNGTNCCN GTNMGNATHGAYGARMGNGTNATHTGYTTYMGNGARAAYGGNAAYCCNATHTCNACNAAR GGNGAYTCNGGNGGNCCNYTNYTNTGYMGNAAYAAYAARACNGAYGCNTAYGTNTCNGGN ATHATHTCNYTNGARGTNAAYMGNACNYTNGTN---------------GTNACNMGNGTN TCNAARTAYTTYAAYTGGATHMGNGARACNYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGNCARGARCCNTCNMGNTTYYTNATHCARGGNYTNGAY GCNGCNGGNAARACNAGYYTNYTNTAYMGNYTNAARYTNGGNGARGTNGTNACNACNATH CCNACNATHGGNTTYAAYGTNGARACNATHAARACNGTNGGNGGNACNGARYTNACNGGN TGGGAYYTNGGNGGNMGNGAYAARATGMGNCCNYTNTTYMGNCAYTAYTAYGCNAAYACN GCNGGNYTNATHTAYGTNATHGAYAGYGCNGAYMGNGARMGNYTNGARGAYACNTTYGAY GARYTNAAYMGNCARGTNYTNTCNTGYGARGARYTNCARAAYATHGTNGTNATGGTNYTN GCNAAYAARCARGAYYTNAARGAYGCNYTNAGYCCNGCNGARATHGARGTNCARYTNMGN AARCARTGYMGNATHGGNTAYGGNATHACNGTNTTYGTNATGCCNACNTCNGTNATH--- GAYGTN------GGNGTNTTYGAYGCNTTYGARAARTTYGCNMGNATHGTNAARGAYAAR AAR--------------------------------------------------------- ---------AAYGGNAAR------------------------------------------ ------------------------TTYTGYCAYGCNTGYTGYATGYTNACNTAYGGNTGY TGYTAYAAYGGNGCNYTNGAYCAYYTNMGNATGCARATHTGGAAYATGTGGTAYTTYTGG TTYTTYATHATHTTYACNATGATGTCNTGYTTYGGNGCNTGYGGNTAYTAYMGNMGNCAY MGNATGGCNYTNTTYACNTTYMGNCCNACNTCNATGGGNAARTTYTCNGCNGTNTGYAAY GCNGTNAAYACNGCNAAYTCNAAYATHAGYATGGTNGAYGTNTAYGARCCNCCNYTNAAY MGNCCNGTNATHACNYTNAAYGGNGARGTNAGYGAYGGNAAYGTNGARCARATHACNAAY MGNCARCARGCNCARGTNTCNTGYMGNATHGAYGGNGGNTAYCCNGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNACNTGGTGYMGNAAYATHACNATGACNMGNYTNYTNMGNCAR GARGAYAAYGCNGAYGAYGTNGCNACNGARGARGAYACNAARCCNAARMGNAARATHGTN GAYGTNGARACNAGYATHMGNTAYYTNAAYAGYAARGCNTTYGTNGARGGNTAYGGNGAY AARCCNGTNTGGTTYCAYTAYMGNMGNAAYTTYAARGGNACNATHATGCCNCCNACNMGN AARMGNTGYATHMGNAARGGNGARATHGCNACNTCNAGYCCNTGYCCNGTNTGYMGNGAY GARTAYYTNYTNYTNGAYGCNAARAAYACNAARYTNYTNGARCARTTYATHTCNCCNTAY ACNGGNGAYATHYTNGARTCNATGAARACNGGNYTNTGYCARCARCARCARMGNACNYTN ACNYTNGARGTNYTNMGNGCNTGGGAYCARGGNTAYYTNGARATGAARGTNCCNTTYMGN TCNTAYGAYTAYAAYGAYTAYAARAGY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GTNGAY TCNGARGTNGAYCAYGAYCARATHCCNAAYCCNYTNGAYGARYTNTTYGAYGARYTNGAY GAYTCNGAYTCNGGNCCNGARYTNGAYACNATGAGYGTNATGTCNACNCCNAARCCNAAR YTNMGNCCNTTYTTYGCNAAYMGNGGNACNACNCCN---GCNYTNGCNYTNCCNAARACN ACNTCNCARGARGCNTTY---------------------------GARGGNGARAAYCCN TTYYTNGAYYTNGTNYTNGCNAAYTCNTCNTTYYTNGAYGAYAGYTCNTCNMGNACNAAR TGYATHCARTGYAAYAARTCNMGNAARTAYTAYTGYTAYACNTGYAAYATHCCNYTNCCN CAYATHCARGAYAARYTNCCNAARGTNAARYTNCCNYTNAARGTNGAYATHATHAARCAY CCNAARGARYTNGAYGGNAARAGYACNGCNCCNCAYGCNTCNATHYTNGCNCCNGAYGAY GTNACNATHTAYACNTAYCCNTGYATHCCNGAYTAYGAYTAYCARAARGTNATHGTNATH TTYCCNGGNAARGAYTCNATHAAYYTNGAYCARTTYAARTCNACNAAYGAYGARACNTCN ------------------------------------------------MGNGAYAAYGAR GARGGNGCNAARGCNYTNTCNAAYGGNAAYGAYGAYYTNAARCCNATGTCNACNAGYAGY CARTGYACNGTNGGNACNACNYTNACNAAYTCNTCNGGNACNACNACNACNGARTCNAAY CCNACNGAYGAR---YTNCARCCNTCNAAYATHGCNTGYAARTCNAAYAGYAARMGNAAR YTNATHYTNACNGARGTNTAYGAYGARATHTCNGAYACNGARCCNACNGARGAYAAYGTN AARTGYTCNMGNAGYTGYYTNAAR------------TCNTGYCCNTTYGARAARGTNATH TTYATHGAYTGYACNTGGAAYCARACNAARCARATHGTNGARGAYGARMGNYTNAARGGN YTNAARAARYTNGARYTNAAYTCNCARACNACNAAYTTYTGGMGNAGYCARGARGGNATG CCNAARACNTAYYTNTCNACNATHGARGCNATHTAYTAYTTYTTYAARCARTTYCAYACN ATHTTYYTNGARCCNGTNTAYMGNCAYCARTAYGAYAAYYTNYTNYTNTTYTTYTGYTTY ATGCAYTCNAARATHAARAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AAYTGGACNTTYGCNYTNTAYGGNGCNATHAAR CAYCCNTCNGAYTTYGCNAGYTAYYTNYTNGCNATHTTYATHGGNAAYYTNYTNYTNTAY TGYATGTTYTAYGTNATHATGAARYTNYTNAGYGGNGARMGNATHAGYYTNTTYGTNATH TGYGTNATGTTYATHTCNYTNATHTCNTGGGGNTTYTCNYTNTAYTTYTTYTTYCARCAY GTNACNACNTGGCARAARACNCCNGCNGGNTCNMGNGARGGNAAYMGNCCNTGYATHYTN TTYGGNTTYTAY------------------------------------------------ ------------------------------------------------------------ ---------GAYTCNMGNGCNGARACNGCNACNGTNGAYCCNGCNCCNGTNYTNCCNGAY GARCCNCAYAARYTNGAYGAYMGNAGYAGYYTNTCNGAYGTNAARGARACNGGNGARMGN GGNGARGAYMGNAAYGAYGCNGCNCARCCNGAYGGNACNGARGAYAGYMGNGGNCARGGN CARTGGAARAGYGCNGARCARCARTAYATHGCNTCNGCNGTNYTNGCNCARAARAGYGAR ---------------------CARGARGCNYTN--------------------------- ------------------------------------------------------------ ------AARGARGTNGARGARGARMGNGAYAARATGGTN--------------------- ------------------GTNGARAARACNTCNYTNCARATHAARGAYYTNCARGARMGN YTNGCNGTNYTNGCNMGNGARGGNGARGARAARGAYAARAARATHCARCAYYTNGARGAY GARYTNMGNTCNACNAARMGNGAYYTNCAYCARMGNGARGAYCARYTNAARGCNYTNGCN GCNGCNGCNTCNGGNGGNGGNGAYGCNCCNAARTCNAARACNTGYGTNGTNATG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNTTYAARAGYGAYYTNTCN YTNGARAARYTNTAYCCNAAYTCNAAYACNGAYTTYATGMGNCARTCN---GARTCNAAR CARGCNTCNACNGAYACNGAYAARTTYTCNGGNTTYATHCCNGTNGARCARYTNGARATH ACNCAYAAYMGNAGYAGYGGNCCNGGNGGNCARAAYGTNAAYAARGTNAAYAGYAARGTN GARGTNMGNTTYCAYGTNGARTCNGCNCCNTGGATHCCNCARTGGGTNAARCCNMGNYTN ATHGAYCARGARCARAAYMGNATHACNAARGARGGNTTYYTNATHATHAARTCNGAYATG ACNMGNAARCARATHYTNAAYCARGCNGAYTGYYTNAAYAARATHMGNAAYATGATHCAY CARGCNTCNGTNYTNCCNAARGARYTNACNGARGAYCARATGMGNATHAARGARCARMGN YTNATGAARGCNAARTCNGGNATHYTNAARGARAARMGNAAYMGNTCNYTNYTNAARAAR TCNMGNTCNGCNCARGAYYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNGARTTY CAYGGNYTNTTYCCNYTNGCNTCNTCNYTNAAYCAYTCNTGYTTYCCNAAYGCNGTNGTN GARAGYGCNGARGTNGGNCCNAARCCNGGNATHGTNGTNMGNGCNYTNMGNGAYATHAAR GAYGGNGARGARATHGARATHGCNTAYGTNGAYCCNYTNATHGARMGNGGNGARMGNMGN ACNYTNYTNTGGMGNAARTAYMGNATHACNTGYGAYTGYYTNMGNTGYATHCAYGARGGN ATGGGNCCNCAYMGNTGYACNAAYTGYGGNAARAAYGCNAAYAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TAYTTYAARACN YTNATGGGNGAYGCNGCNGTNTCNGAYTGGATGTCNTCNATHATHGARYTNAARAAYAGY GTNATHGGNAGYAAYMGNGARAARACNAARGTNATHCARMGNGGNYTNGTNCCNMGNYTN YTNAAYTGGGTNGARGAYGARAAYTGYCCNGCNGAYYTNAARACNGARTCNGTNATHGTN YTNGGNAGYYTNGCNAARGGNGGNAARGAYACNGTNACNCARYTNGTNCARTTYAARGTN GTNCCNACNYTNYTNYTNTCNYTNTCNAAYCCNAGYYTNAARTAYAGYGARGCNGTNYTN MGNTGYYTNMGNTCNATHTTYATGGARAAYACNGAYTGYATHGARYTNYTNTAYCARGAR TCNAGYTTYGGNTCNTCNTAYATHCCNACNTTYYTNGCNATGACNCARCARTCNGARGTN TGYCARGARTGYGTNACNAAYATHYTNGCNTGYGCNTGYGARACNAARTCNCAYCARYTN GTNYTNCAYATGAAYGARGCNGTNTCNATHYTNTCNCCNYTNYTN---CARTCNAARMGN TTYAARATHCARATGCCNACNYTNAARTTYTTYGCNAARYTNTCNTAYMGNAAYGTNCAY GTNTGYYTNGAYATGGTNMGNGCNTAYGARYTNGTNCCNATHTAYGARGAYYTNATHGGN MGNGAYAARCCNCCNGARATGCARATGGCNGCNGCNGARGTNATGACNAAYYTNCAYMGN TGYGGNGCNATHCCNGCNAGYGAYTTYATHATHAGYMGNAARACNYTNGGNACNYTNGTN MGNATGTGYYTNCAYGAYMGNACNGTNCARGARAAYGTNMGNGGNGCNGARYTNYTNGCN TAYYTNGTNGARATGGAYCCNGARYTNCARYTNACNGCNAGYTAYACNTTYCAYYTNATH AGYGCNYTNTCNTAYTGYYTNGAYGARAARAAYYTNGCNGCNMGNYTNTCNYTNTCNGAY CARGAYGTNGAYTGGACNGGNGARATGMGNMGNGCNGCNTTYYTNGCNTTYGCNTCNATH AGYGCNAAYGAYGARGARATHMGNGARAARGTNATHAARCARAARGAYYTNATHTCNAAY YTNCARAARGCNGTNGGNAGYTCNGAYGAYMGNGARGTNGCNGCNGGNYTNAARTGYYTN CARTCNYTNACNMGNTCNGTNCARCARATHMGNACNGTNYTNCAYGAYAAYGCNGTNTGG AARCCNYTNYTNGARAARYTNMGNGCNGGN---------------AAYMGNGARATHATG ATHYTNTCNATGGCNTGYYTNTGYAAYYTNGTNYTNGARTTYTCNCCNAGYAARGARGCN YTNGTNGARAAYCAYGCNGTNGAYGTNYTNTGYGAYYTNTGYMGNAGYGAYGAYACNGTN GTNMGNYTNAAYGCNACNTGGAGYATHATGTCNATGTCNTAYTGYGCNTCNGAYAARYTN MGNATGAARATHATHGARAARYTNGGNACNGARACNATHGTNAARMGNATHCARGAYCCN GTNYTNYTNATHMGNGARAARGCNYTNTGYATHGTNMGNAAYYTNYTNACNACNAARATG TCNATHGAYAAYACNYTNAARYTNYTNGGNAAYGARGTNATGGARGCNGTNTTYGGNATH YTNATGGAYCCNGAYATGCCNCCNCAYATHGTNTCNCARGCNYTNTGYGCNGTNAGYAAY ATGGCNGAYGGNCCNTCNTGYAARAGYTAYATHATHTCNAARACNGAYGARGTNAAYTCN GTNATHAARTAYYTNCARTAYCCNGAYAARGAYYTNCARYTNCCNGCNATHCARTTYGTN AGYAAYYTNGTNGAYCCNACNGAYGAYGGNTTYGGNCCNTTYCCNGGNGCNAAYTCNTGY CARMGNATGTAYCARYTNAARACNYTNGGNGTNCARTCNYTNYTNGARTCNYTNYTNGGN ACNGGNGTNGAYGARGTNGARYTNAARGCNCARCARACNYTNAARTAYTTYGCNATGTCN ACNTAYATHMGNMGNTAYGCNAARTAYYTNAAYGARAARGCNGTNTCNTAYMGNYTNATG GCNTTYGAYTTYTGYAARGTNAARMGNGGNAARGAYGAYGGNYTNYTNMGNACNATGAAY ACNGARAARYTNYTNAARACNYTNCCNATHYTNCARCARCARYTNGAYGCNYTNYTNGAR TTYGAYTGYTCNCCNAAYGARYTNACNAAYGGNGTNATHACNGCNTGYTTYATGYTNYTN TTYAARGAYYTNATHMGNYTNTTYGCNTGYTAYAAYGAYGGNATHATHAAYYTNYTNGAR AARTAYTTYGARATGAAYAARAARCARTGYAARGAYGCNYTNGAYYTNTAYAARAARTTY YTNGTNMGNATGGAYAARGTNTCNGARTTYYTNAARGTNGCNGARAAYATGGGNATHGAY AARGGNGAYATHCCNGAYYTNGCNAARGCNCCNGCNAGYYTNYTNGAYGCNYTNGARCAR CAYYTNGCNTCNYTNGARGGNAARAAR---ACNGCNACNACNCCNACNGGNGCNAGYAAR CCNTCNGGNTTYACNACNGCNYTNAAYAAYATGTCNAGYAAYACNTTYAAYYTNAGYGAR GCNGAYAARMGNAARATHYTNGAYGAYGARAAYCARCARYTNCARMGNCAYAARGGNYTN CARGAY---GARCAYAARATHCARACNGAYATHTCNCCNCAR------AARGCNGCNCCN ACNAAYAAYCCNTTYTCNAGYCCNAAY---TCNTCNTCNGCNCARCARCARGAYYTNTTY GGNTCNCCNGTN------------GCNGCNAAYAARGCNAGYGAYGAYYTNYTNAGYYTN AGYGCNAAYCCNTTYGCNGAYAGYGTNTCNAAYGCN------------------TAYCCN GCNCCNACNGCNAAYAGYAAYCCNTTYGGNACNCCNGCNTTYCARACNAAYGGNTAYTCN GCNGCNGGNAAYAAYTTY------GAYGCNGAYTTYGCNAGYGCNTTYAAYAAYTCNGGN GCNAAYTCNCARCCNACNTCNAGYATHACNGCNCCNACNTCNACNGCNCCNCCNGCNGGN TTYGAYGCNTTYGGNGARGTNATGATGCCNATGAAYAARTCNCCNTCNCAYCARGCNCAR GGNGGNCARGCNAGYMGNTCNYTNGGNGGNGAYYTNGAYTCNTCNYTNGCNTCNYTNGCN TCNAAYYTNTCNGTNAGYGGNGGNACNGGNCARYTNAARAARGAYCAYCARTGGCAYCCN AARGGNGARAGYAARYTNACNGGNGGNCARTCNTTYCARMGNCCNCCNATHGCNACNTCN ACNACNCCNGCNGCNCCNCARTGGGGNCARCARCCNGGNTTYCARCAR---------CAR CCNATGGGNGTNCCNGGNGGNCARATGATGTAYGGNCARCARATGGGNATGCCNATGGGN CARCCNATGATGCARCCNATGGGNATGATGGCNATGCARCARCARCCNATGCARGCNCCN CARATGGTNGGNAAYCCNGCNTCNTTYGGNCARATGGCNCCNCARACNCARCARATGGCN CARCARCCNCCNCAR------------TCNAARATHAAYGAYCCNTTYGGNGCNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CCNCCNCCNGARCCNACNTTYAAYCCNYTNTCNGAYTGG MGNMGNAGYAGYGGNTCNGAYAGYMGNAARGARGGNTTYGARMGNCAYGAYMGNCCNGAY AAYAARMGNCAYCCNMGNAAYTAYGGNGGNGGNTCNGAYYTNTCNAARGTNAARGAYAAY ATHAARAAYATGMGNGARAARGARMGNGARMGNCCNGGNGGNAAYAARCCNYTNGARATH GCNATGACNGGNMGNGARMGNAARAAYCAYGARCARTGGAARCAYGARMGNGAYMGNTTY GAYAAYGARMGNATHCARMGNCARYTNACNGAYGGNGGN---TGGAARMGNGARTGGGAY CARGAYAARGTNACNYTNGAYTAYGAYGAYAAYTCNTAY------GGNAARTCNGARCCN CARAARMGNCCN------------------------------------------------ ------------------------------GCNGGNMGNATHGGNAGYGGNMGNTTYGAY MGNGGNGAYAGYMGNGARGAYMGNCCNCARGCNCCNACNMGNGARGGNAARGGNATGTCN CARCCNAAYTCNCARCCNCARCARCAYAAYGCNAAYAGYCARTAY---CARGCNCCNATH AGYCCNCARCAYTCNACNCCNTCNMGNCCNAARGGNMGNGGNMGNGGNMGNGGNMGNGGN MGNGGN---GTNGGNGGNCARGGNGGNAGYAGYGGNCCNGGNGAYAARTCNCCNMGNCCN MGNACNTGGTCNGGNGGNGAYGAYMGNTTYGTNGARTGYCARAARGARATGYTNGTNGTN AARTTYGAYAAYACNGTNGGNGAYGAYTCNGTNGARGTNGARTAYGARAAYGGNGCNCCN YTNTCNCCNACNCCNTCNTCNAARTCNTCNGGNTCNACNCARGGNMGNGGNCCNACNGGN MGNACNTCNAAYCARGGNACNAAYMGNAAYAARGCNGGNMGNCARAAYAAYCCNAARTCN GARMGNGCNCCNAARGCNAARGTNGGNAGYGGNMGNATGACNGGNCAYCARACNGGNAAY GAR---------------GGNGAYGTNTCNAAYATHACNAAYCAYMGNCAYTCNTAYCCN GCN---GGNTCNAARGCNMGNACNTGYTCNTCNCAYTCNCARAGYCARGGNGAYAGYGAR GARTGGGARGAYTGYACNCARTCNTCNGGNGCNCCNGARGAYGAYATHAAY--------- ---------AAYCCNYTNYTNCAYGTNGAYTGYCARYTNAAYCCNGAYGCNCCNGARTTY YTNCCNACNTCNCCNGAYTTYYTNAARACNCCNCCNGGNCAYGTNAARGTNYTNAAYTGG GCNGGNCCNCCNACNTCNCCNCARTCNAAYYTNACNCARCCNAGYYTNACNTCNCCNTCN YTN------------------------TCNCCNMGNCCNCARTCNCAR------CCNGAY GARGCNTCNAAYCAYTCNTCNGTNTCNTCNCCNGGNTCNTCNGCNTCNACNMGNGCNAAR ACNMGNMGNGARGARATGGAYATGATGCCNCARCCNGAYGARCCNATGCCNCCNCCNTTY YTNYTNGARATG---------------AAYGGNACNCAYAARCARGARGTNAARGGNGTN GARAAYGARGTNATHGCNAAYGAYGCNGTNATHGAYGAYGARGAYGAYGGNGARAARTTY GTNGAY------------------------------------------------------ ------------------YTNACNGAYGTNGCNAAYGTNMGNACNATGGARCAYGGNYTN YTNAGYYTNYTNAAYGAYTTYCAYTCNGGNAARYTNCARGCNTTYGGNAGYAAYGCNACN TTYAAYAARATGGAYGCNATHMGNYTNCARCARGARCARYTNGCNAARCARCAYTTYGAR YTNGAYYTNYTNCCNMGNTCNGCNTCNAGYMGNYTNAAYTCNGARGARACNMGNAARGAR AAYAGYGARAARATGGAYAARYTNATHGARCAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNAARAAYTTYAARAAR TTYAARAARACNATHCAYTCNGGNAGYCARGGNYTNCCNACNATHATHGGNGGNMGNGAY YTNGARCCNCAYAARAGYAAYMGNYTNAAYCAYATHGAYGARATG--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TCNAARCAYCCNCAYGGNACNAGYCCNACNACN AAYAGYCAYCCNCAYACNGGNCARGCNMGNCCNYTNGTNTAYGGNAAYGAYAAYAGYACN GTNAAYMGNCARTCNMGNACNCARACNACNMGNCCNGAYCCNATHCCNGGNCARCCNTAY GCNGGNGCNCCNGCNCARMGNATHGGNAGYGCNCCNYTNMGNAARATGGGN---AAYCAR GGNACNATHMGNCARGCNGCNGGNAGYMGNGCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------MGNCARTTYCARGGNATGCCNATGCCNTCNGCNCCNGGNMGNCCNGAYATH GGN---CARCCNAARAARYTNTGGGAYGAYGAYGCNCAYAARCCNGGNGAYCCNAAYCAR TCNGGNATGTTYCAYCAYGGNTGGACNACNMGNGAYGAYTCNTGGATGTCNGGNCCNTCN GARACNAGYAAYCARATHGGNGTNAAYATGGTNGARTAYGTNYTNGGNGGNGGNTCNCCN AAYAARATHGAYGCNGGNACNATGGGNMGNATHAARCCNTTYGARAARAARAAYCCNGAY ATHCCNTCNCARTTYGARGARGGNGTNGAYGAYGGNAARGAYGTNYTNCARGGNAAYGGN YTNYTNCAYAAYGGNYTNGAYGAYACNGGNTTYMGNGGNAGYMGNCARAAYTCNCCNACN GAYGARGARMGNCARGGNGTNGTNGGNYTNCCNATGGAYCCNCARGAYYTNCAYATHMGN GAYGCNGGNAAYTTYYTNGAYACNGGNCAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AAYAAYTCNCARCCNATGGAYGGN------CCNGARATH GAYACNTGGACNAAYGARACNGCNGARACNAARGTNACNAAYAARGAYACNGAYTGGAAY AGYTGGAAYGAYTCNTGGGTNAAYGAYGARGAYCARTGGACNGGNACNYTNGARGARACN AARGTNTTYACNCCNTCNCAYGTNAARATGCCNGARCCNGAYCCNGTNAAYAAYGARCCN CCNAGYTCNYTNGGNCARMGNYTNGAYGTNGGNAGYYTNTTYGARAGYGCNAARTTYTCN AARGCNCCNGAYTAYAGYAARCCNACNGGNGAYTCNTAYATHACNCARTTYAAYCARGCN GCNACNGARTCNATHAARAAYTCNATHGGNATHGGNTCNTCNCCNMGN------------ ---CARCARATGGGNATGTCNCCNCARAAYTCNTCNACNTCNYTNGGNYTNTCNAGYYTN TGYCARAAYACNGGNCARGTNCARGGNAGYTCNGTNYTNTCNTCNYTN---CARCARACN AGYTCNCARCCNAAYACNATHCCNCAYGGNATGAGYCARYTNTCNCARATHTCNCAR--- ---------------------TCN------------GGNCCNAAYCCNAGYYTNTCNCAR ATHGGNATGGGNAAYGCNTCNGCNACNGGN------------------------------ AAYCCNTCNCCNCARCARTCNMGNATHCCNTCNGTNGTNCAYCARCARCARCAR------ ------------YTNCCNCARTCNACNATH---AAYAGYATGCAYCARMGNAAYAARCCN CARMGNTCNAARYTNCCNCCNCCNTCNAARATHCCNTCNACNGCNGTNGARATGCCNGGN CAYATHCCNMGNAAYCCNCARYTNGAYGTNCARTTYGGNYTNGAYTTYGGNTCNGARCCN TCNGTNCARTTYGGNTTYGGNGGNAGYGGNGAYAGYCCNGCNATHACNACNTCNTAYACN AAYGTNTCNAAYGGN---CCNGAYGTNATHCCNAAYCAYYTNAAYCARAGYCAYGTNACN CARTCNGCNGGNGAYGGNAAY------TCNACNATHATGCCNTCNCCNACNGTNAAYTCN GGNAARCCNCCNCCNGGNATHGARTCNCARGCNCCNAAYMGNTCNGGNGCN---TAYCAY AAYTCNGTNTAYCCNGCNCCNTCNCCNAAYTCNGARAGYCARTCNCAYGARYTNGAYCAR AGYAARGTNAAYGARGCNATHCCNTTYYTNCCNACNCARYTNGARMGNAARTCNAGYCCN ---ATGTCNGCNCARMGNCARGGNCARTCNAAYCARAAYYTNAGYTCNGGNTCNATHACN CCNAGYAARAGYGARTCNACNAGY---GCNGCNGCNAAYAGYTAYTCNTCNGCNAAYGGN TAYTCNGTNTCNTCNTAYCARAGYCAYCCNAARGGNTCN---------ATHTCNCAYGCN CCNAAYTCNCARCCNTCNCARACNTCNTCNTTYCCNGGNCCNTAYCCNGTNAAYCARTCN TAYCCNCCN------CCNCARACNCARTTYCCNACNCCNCCNAAYGCNGCNCCNTTYCCN ACNTCNCARCARCCNTCNCARTAY---------AAYACNAAYGTNTCNCARAAYCARTTY TCNTCNGGNCARAAYCARTAYTCNGTNGGNACNTCNACN---------YTNTCNCAYCAR ACNCARTAYTCNGGNGGNGGNCARAAYACNTAYGGNAGY---GGNCCNTCNCARTAYGCN GCNTAYCARAAYAGYAAYTCNTTYCCNCCNCAYCCNCARTCNCARTCNAAYTAYTCNAAY CARAAY------------GGNGCNAAYYTNTAYCCNACNTCNACNCCNTCNAGYGTNCCN ACNTAYTCNTCNCARTCNAAYTCNTAYCARTCNCCNTCNGCNGGNTCNTAYCAYACNTCN MGNGARGGNCCNACNAGYGTNGCNGTNAGYACNCARTCNAGYTCNAGYATGCCNTTYCCN AGYCARCCNCARGCNTCNAAYYTNAARCCNACNTCNTCNCARAAYCCNTCNAAYTTYAAY ACNCARAAYTAYAAYGCNAAYCCNGCNCCNYTNCARCCNTCNTCNYTNGCNAAYAARYTN GGNGARAGYYTNTCNAARATGACNYTNAARGAY---ACNGCNGTNYTNGAYAAYCAYCCN TCNGCNCARTTYGARCAYCCNTCNTCNACNTCNACNGTNCCNACNACNGTNAGYYTNCCN TCNAGYTCNTCNCCNGCNTCNYTNTCNACNGGNACNAAYACNATHTCNTCNACNTCNACN GTNACNTCNGTNTCNTCNAAYTCNMGNGTNACNTCNATGCCNTCNACNTCNGGNAARGTN CCNCCNAAYYTNCCNCCNGGNGTNCCNYTNGTNGGNCARTAYATHATGGGNCARAAYACN ATHCCNCCNTTYTAYAGYGTNCARCCNCCNYTNTAYGGNTAYGARGAYATGCARYTNYTN CARCARMGNATGCCNATG---ACNGGNAGYTAYTAYGAYGTNAGYGCNTTYCCN---GCN CCNGCNGGNTCNGCNYTNCCNACNGGNMGNGAYCARCARCCNCCNATHCCNAGYGTNCCN TTYTCNGGNACNTCNGAYACNAARYTNACNMGNGTNGAYGCNCARAGYCCNAAYGCNTCN AAYCARCCNCARAAYGCNCAYTCNGCNCARCARCCN---YTNTTYAAYTTYCAYTAYGGN TAYTAYTAYCCNTCNATGTTYCCNGGNGCNGCNGGNYTNCARTAYCCNACNACNGTNTAY CCNATHCCNCCNGTNACNAAYACNGCNGCNCAYCCNGGNACNACNTCNAGYACNCARTTY CARAARTCNTAYCCNTCNCAYGTNTAYACNACNAARGGNTAYGAYGARATGAAYCARGTN CCNGAYTTYTCNAARACNGGNTAYGGNAGYGCNCARACNGCNGGNAARGCNGCNGGNACN MGNATGTCNACNMGNTCNGGNACNAAYGARATHACNCCNAAYGCNTAYAGYAARTCNCAY GCNCAR---GGNTTYGAYAARCARGGNTAYCAYGGNGGNACNCCNCCNCCNTTYAAYYTN CCNATGGCNTCNGCNGCNCARACNGGNCCNATGGGNGCNCCNACNACNCCNTAYGGNGCN CCNTTYYTNCCNGTNATGGCNGCNCAYCARCCNCAYTCNCARATGATGCAYCAYCCNATG CARCARGAYTCNAAYACNAGYAGYTCNMGNGGNATGAAYCCNGCNGGNGGNCARGGNAAR TCNGGNGCNGCNAARTCNTTYGGNGGN---CCNCCNTAYTGGAAY--------------- ---TAYYTNCCNYTNCCNCARYTNTGGGGNGTNYTNTTYTTYYTNATGYTNTTYACNYTN GGNYTNGAYTCNATGTTYAGYAGYGTNGARACNATHAAYACNGTNGTNATGGAYGTNTGG CCNTCNYTNGTNAARMGNTGGMGNGGNGGNTTYTCNGCNGCNACNATGYTNGTNATHACN YTNGCNGGNYTNATHTTYGTNACNMGNGGNGGNATGTAYTGGTTYCARYTNTGYGAYTGG TAYATHGCNGCNTTYGCNATHYTNYTNCARGCNGCNATGGARTGYYTNGCNATHGCNTGG ATHTAYGGNATGGARMGNTTYAGYMGNGAYATHGARYTNATGATHGGNMGNGARCCNYTN ACNTTYTTYGTNGTNTCNTGGAARATHGTNACNCCNACNATHYTNYTNATHATHTGGGTN GTNACNYTNGTNACNTAYAARCCNCCNACNTAYGARGGNTAYGTNTTYAGYMGNGGNGCN GARATHGGNGGNTGGGTNTTYGCNGTNATGCCNTTYATGGCNGTNGTNGTNTAYGCNGTN TAYGARGTNATGAARCAYCCNGGNACNYTNMGNCARMGNYTNGARGCNGCNACNACNCCN ACNGCNGARTGGGTNCCNAAYATGCCNGAYTCNAARGAYACNTAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TCNYTNGTNYTNGTNATGYTNGGNAARTTYACNCCNGAYATGGTNYTNTTYTCNGAYATG GCNGARTTYATHTAYGTNATHGTNGAYATHGTNGCNGGNTTYYTNATHTTYYTNGCNGCN TGYATHYTNTCNGCNGGNACNAAYTCNACNTGYGAYGCNATHGARTGYGAYAAYTCNGTN TTYTCNGAYACNATHTCNGCNTCNMGNGCNGCNCARGCNGGNGCNTGGATHAGYACNTTY YTNTGGATHTTYGTNGCNATHTGYGGNTTYATHACNYTNTGGMGNGCNGGNAARATHCCN TTYYTNTCNGGNGGNGGNGCNAARCCNTCNGAYCARGGNCARGGNCCNGCNGAYCCNAAY CARCCNCCNATHGARACNCCNCCNAAYAAYCCNGAYGARGGNCCNAARTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TTYAARTAYMGNATHCARMGNMGNYTNTAYCAYGGNTGY--------------------- AGYGARAARGCN---ATHTCNACNGCNTCNTTYCCNYTNACNGARGTNGCNATGGARTAY TTYCARGAYAGYTTY---GAYTGYGARGGNYTNGGNMGNYTNGAYATGCCNACNACNTCN ACNGTNACNAARAARAAYAARGTNTCNCCNTGYTCNATGGTNYTNTCNATGYTNTAYGCN AARMGNYTNMGNCARMGNAAYAARGARTAYYTNCARTCNATGTCNTCNACNGAYGTNTTY TTYATHTCNATGATGATGGCNAGYAARTAYYTNTAYGAYGARGGNGTNGAYGARGARGTN TAYAAYGAYGARTGGGCNGAYAGYATHGGNCARGAYGTNGARGAYGTNAAYCAYATGGAR ATGGAYTTYYTNMGNGARATGGAYTGGCARYTNTTYGTNAARCCNGARGARTTYGAYTCN GCNYTNACNGAYGTNGARMGNMGNYTNGCNYTNMGNGARGGNYTNAARMGNGGNTGGTTY AGYTAYACNGARATGGCNGTNYTNYTNGAYTGGGAYCCNGTNTAYCARATGTGGAGYCAR TTYAGYACNGAYTGYACNAARGTNGTNTCNGTNATGTCNGCNGTNTAYGTNGCNAGYYTN YTNAGYATGATGGGNTCNGCNGCNATHGCNYTNCARYTNTCNGGNCCNYTNGCNACNGCN ACNATHTCNGTNYTNTCN------------------------------------------ ---AARTGYTGYCCNMGNTCNTGGAAYTAYGGNTGYMGNCAYACNCAYATHMGNATGCCN TGYTTYMGNAAYTAYTAYCAYGGNMGNMGNGARACNTGYTGYCCNTTYTAYCCNACN--- ---ATHTAYACNGCNMGNTGYYTNTGYGAYAARTGYCAYATHCARACNAAYGCNTGYGTN CAYCCNGGNMGNTGYAGYAARMGNTAYACNAARMGNAAYTTYATHGCNATHTGY---TAY AAYTAYYTNGGNTGGAAYYTNMGNTTYTTY---MGNAARTGGYTNCCNTCNAGYTGYTAY TGYMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGTNTGYGTN CCNTGYTTYYTNATHCCNGTNATHYTNTGGGTNTTYCAYAARTTYATHCARCCNTGGYTN TCNAARYTNTGGAGYGGNTCNGARAAYTAYGTNACNAGYAAYYTNACNTGYCCNYTNCCN CARAARAARAAR------------------------------------------------ ------------------------------TAYTAYTCNGGNACNAAYGCNGARCARGAY ATHMGNTTYGCNGAYAARCARAARAARYTNATGAARTCNATGMGNTTYGGNGARAAYATH AAYGTNAARATHGAYATGACNAARGTNACNGTNGAYAGYATHAARCCNTGGATHGCNCAR MGNGTNACNCARYTNYTNGGNYTNGARGAYGAYGTNATHGTNYTNGAYACNMGN------ ------------CAYCCNGAYGGNAARGAYATGCARATHYTNYTNACNGGNTTYYTNAAY AGYAARAAYGCNMGNATHTTYGTNACNGARYTNTGGAARCAYYTNTGYAGYGCNCARGAR AAYATHACNGGNATHCCNTCNGARTTYATHGARCARAARAARAAYGARATHAARCARMGN CARGARGARCARGARMGNYTNCARGARGARATGAARAARAAYGARGARYTNATHAARGAR CARYTNYTNAARGARMGNMGNGARATHGARAARAARGAYYTNGAYAAYYTNTCNCCNGAY MGNCCNAARACNGTNGAYGGN------------------------AAYATHAARCCNYTN ATGGAYATHGGNGAYGGNCARGAYGGNAARAARGARGARGAR---------AARTCNGAR CCNAGYGARGAYAARGARAARAARGARTCNAARGAYMGNCARAARGAYAARTCNCCNGAY MGNAARAARGAYAGYMGNGAYAARGARMGNMGNAARTCNMGNTCNCCNGAYAAR------ ---------------GARMGNMGNMGNCAYTCNMGNTCNCCNGAYMGNCAYMGN---GGN MGNTCNMGNACNCCNGARMGNCAYMGNMGNGARMGNGAYMGNGARMGNTCNMGNCAYGAY CAYGGNMGNCAYTCNCCNGCN------MGNMGNAARTCNMGNTCNCCNMGNMGNMGNTCN CCNCCNMGNCAYMGNTCNCCNAGYCCNMGNCCNGCNTCNCCN------------------ ------------------------------------------------CAYAARMGNAAR TCNCCNMGNAARGCNGCNCCNCCNAARMGNAAYAARTCNGGNAGYTCNAGYAGYTCNAGY GAYTCNGARGAY---------GGNTCNGGNAARGARGGNTCNGTNGAYAARTCNGGNGTN CARCARMGNMGNAAYTAYMGNAARCAYGAYGARGGNAGYGGNAARGARTCNTCNTCNGAY TCNTCNGAYAAYCARAARAAYAARMGNMGNGGNCCNCCNCCN------------MGNGAY MGNMGN------------TAYATHMGNMGNAGYCCNTCNCCN---------MGN------ ---MGNMGNTCNCCN---CCNCCNMGNMGNTCNCCNCCN--------------------- ------MGNMGNTTYAGYCCNCCNMGNMGNMGNTAYCCNTCNCCNCCNMGNMGNMGNAGY CCNCCNMGNAGYATGTCNCCNMGNMGNMGNTCNCCNCCNCCNCCNMGNMGNMGNAGYCCN CCNCCNCCNCCNMGNMGNMGNATGTCNGTNTCNCCNMGNMGNMGNMGNTCNCCNTCNCCN ATGAGYMGN---MGNMGNCAYTCNMGNTCNCCNTCNAAYTCNCCNGTNAARMGNMGNMGN CCNTCNCCNCCNMGNGCNTCNTCNCCNCCNGCNAARGCNAARMGNAARGARTCNCCNGCN GCNTCNGARTCN---------GGNAGYTCNAGYTCNGGNGARTCNTCNCCNTCNCCNCCN CCNGTNAARMGNAARAGYAARGARGCNCCNCCNCCNAARMGNAARGTNCCNCCNCCNAAR CCNGCNCARTCNGAYAGYGAYAGYTCNTCNTCNGGNTCNGARGARAGYGARGAR------ ------GAYTCNGAYTCNGARGARAARTCNGARTGGAARGARGCNAGYCCNCCNMGNATH GTNAARGCNCCNCARAARTCNCARACNCCNGTN---------------GAYAGYAAR--- ------------MGNTCNMGNTCNMGNTCNCCNAARAAYMGNAGYGAYAAYMGNCCNAGY CCNCCNMGNMGNAARCARAAYTCNMGNTCNCCNTCNCCNATHAARCARMGNAARMGNACN TCNTCNCCNCCNCCNCARMGNMGNMGNGGNGGNTCNCCNMGNTCNCCNCCNCCN------ ------------CCNMGNMGNCARMGNMGNAAYACNGAYACNTCN---GAYCAYGARCCN GTNAARMGNGAYMGNAAY---------------TCNAGYCCNMGN---------AARAAR MGNYTNMGNTCNCCNTCNCCNMGNAAYGAYATHGGNMGNCCNGCNMGN------------ ---------CCNMGNTCNCCNCCNMGNGAYAARMGN---------------MGNGARACN GARAGYGGNAARAARAARGGNAARMGNCCNCCNTCNTCNGAYAGYAGYAGYGGNAGYAGY TCNGAR---------------GARGARGARGTNCCNAAR------------CARAGYAAR MGNATGGCNGCNGCNCARCCNCARMGNAARMGNTCNTCNAGYCCN--------------- ------------------------------------------------------------ ------------------------------------------------TCNMGNCCN--- ------------------------------------CCNCCNTCNCAYCARTCNMGNTCN TCNMGNAARGARGAYCAY---TCNCCNCCNMGNAAYGGNAAR------------------ ------------------------------------------------------------ GTNAAYGAYGTNAARGGNAARAARGARAARCCNGTNCARTCNAGYAGYAGYGARTCNGAR GAY---TCNGAYTCNGAY---GCNTCNMGNAARAARAARAARAARAARGARAARAARCAY AARAARCAYAARAARCAYAARAARCAYAARCAYAARAAR---------GARGCNCAYGAR AARGGNGAYGAYYTNGARCARMGNYTNMGNGARAARGCNYTNATGTCNYTN------AAY MGNAARAARGARAARAGYTCNGARGCNCCNGAYTCNGGN---AGYGGNAGYAGYAGYGGN GARGARTCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARGAYYTNGTNGAYYTNGGNTTYTTYTAYGCNGGNTAYTCNGAY TGYGCNMGNTGYTTYTAYTGYGGNYTNGGNYTNAARTAYTGGMGNCCNGARGAYATHGCN GCNTAYCARCAYGCNMGNTTYMGNCCNCAYTGYYTNTAYAAYAARTAYGTNAARGGNCAR GAYTAYATHGAYMGNGTNYTNMGNGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------GAYGARYTNAAYTTYYTNYTNGTNGGNGCNGGNGAYATHMGNCAYATHYTNATG ACNATHGCNMGNMGNTAYMGNCAYAARAARMGNAARYTNAAYTTYTAYGTNGTNGARAAY TCNYTNGARYTNTAYGCNMGNGAYGTNYTNYTNATGATGGTNGTNYTNGARYTNCARGAR CAYATGGGNYTNCARGARAARACNGARGTNTTYYTNGARATHCAYGGNAAYACNYTNYTN MGNCARCARACNAGYGAYTAYATHCARAARATGTCNCARCARYTNATHMGNATGGTNACN AAYTTYGAYTAYATGGARAARAARYTNTCNATHTTYGAYTTYACNCARYTNAARTAYAAR GARMGNGAYTTYYTNGARGGNATHTTYAARTTYTGGMGNGAYAARGARAARGTNAARATG CCNTTYGAYATHACNAARTGYTGGGAYYTNMGNYTNMGNCARYTNYTNGGNGTNMGNTAY GAYAGYMGNCCNAAYACNTTYGAYTGGGAYTAYAAYATGGARATGYTNGARMGNGGNGGN TCNATHATHCAYYTNMGNCARTAYAARTCNTGGMGNGARGAYGGNATHGCNTAYACNATH MGNGARGGNACNTAYGAYATHCCNAAYMGNACNYTNTCNTCNGCNATGGTNTTYAARCAY GCNGGNGARMGNCAYCCNMGNMGNGGNTTYTGGGGNGAYATGYTNGTNTCNCCNTAYGTN ACNTTYGGNGTNGARACNGARGARAARTCNYTNTAYAARAARCARAAYGAYCARCAYACN AARACNGCNGARGAYGTNGCNGARTTYAAYATGYTNTCNYTNYTNCAYGARYTNACNACN AAYACNAARTAYGARCCNCCNACNGTN------ACNCCNCCNACNAARGARGAYAAYTCN GAYAGYAARACNGCNACNYTNGARGARATHATHGARGARAAYGTNAARGGNGAYGGNTCN ACNGARAAYGTNGAYCARACNGTNGAYAARCARGARGTNGARATHACNCCNAARGTNGCN GTNGAYAGYGAR---GAYTAYGARTGGATGTCNYTNGAYGAYATHAARATHACNTTYYTN CCNGCNGCNTGYATHAAYGAYATHGCNAARAARAGYAARTAYCARAARYTNTTYAAYGCN GCNTTYTTYTCNAAYAGYATGGCNCAYYTNYTNACNGARGARGTNACNCCNATGTTYGCN GAYACNTGYTCNGTNGTNATGGARACNGCNYTNTTYATGYTNAGYYTNAARAARCCNGAR GTNAARGARTTYGTNCARAARATHACNGGNATHGCNCARACNGCNGGNTGYGTNCCNYTN GAYGTNGTNGAYGAYYTNCARGAYTCNTAYACNACNTTYTGYTTYCARMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNGTNAAR MGNCCNMGNGGNGTNTCNYTNGARAARGCNTCNTTYTAYCARGCNGAYMGNGAYTTYMGN TGYYTNACNGAYGGNAARATHYTNCCNTTYGAYCAYGTNAAYGAYGAYTAYTGYGAYTGY GAYGAYGGNTCNGAYGARCCNGGNACNTCNGCNTGYGCNAAYGGNYTNTTYTAYTGYGAR AAYAARGCNTAYAARGGNATHTAYATGATHTCNTCNMGNGTNAAYGAYGGNATHTGYGAY TGYTGYGAYGGNAGYGAYGARTTYAAYGGNATHATHGCNTGYCCNAAYACNTGYGTNGAR YTNCARCARAARGARCARGCNGARCARGARGTNTTYMGNCARGCNCARTCNGARGGNTAY AARGTNAARCARGARTAYATGCARCARGGNAARMGNGCNAARGAYGARAARYTNTCNAAR YTNAGYGARYTNGAYMGNGARAARGARACNYTNGCNAARGARAARGAYGCNGCNGARGCN GCNAARAAYGCNGCNGARGARCCNGARAARATHGCNYTNGARGARCAYAARAARGCNTGG GARYTNAARAARGARGARAARAARAARGCNAARGARGCNYTNGAYGCNGCNCARGCNTTY ACNATHYTNGAYTCNAAYGARGAYGGNAARGTNGAYTAYCCNGARYTNATGAARCAYAAR GARTTYGAYATHGAYTCNGAYGGNACNGTNAGYGARGARGARGCNMGNGARTAYYTNGAR GARAGYGARGARGTNGAYYTNACNGTNTTYACNGARAARATHTGGCCNAAYATHAARGAR ATHTAYAARNNNNNNNNNATHCCNGARGARNNNNNNNNNNNNNNNNNNGARNNNNNNNNN NNNNNNNNNGANGARGARAARNNN---------NNNGGNGGNNNNNNN---GARNNNNNN NNNAAYNNNGAYGAY--------------------------------------------- ---------------GARGAYAARGARCCNCCNTAYGAYGARGGNACNGARAARYTNGTN GCNGCNGCNGAYYTNGCNMGNTCNAAYTTYAAYGAYGCNGARAGYAARTTYAARGAYATH GARAARGARATHAGYGAYATHAARAARTAYYTNGARATHGAYTTYGGNGCNAAYCARGAR TTYGCNGCNYTNAARGAYAAYTGYTTYGARTAYGTNGAYMGNGARTAYAARTAYMGNYTN TGYCCNTTYGARAARACNTCNCARGGNAAYAARAAYGGNGGNATGGARACNTCNATHGGN GTNTGGGGNMGNTGGCAYGGNCCNGAYAAYGAYAARTAYGAYACNATGAARTTYGARAAY GGNCARGGNTGYTGGAAYGGNCCNAGYMGNTCNACNATHGTNACNYTNCAYTGYGGNGCN ACNAAYGARYTNACNAGYGCNAGYGARCCNAAYMGNTGYGARTAYCAYTTYGAYTTYACN ACNCCNGCNMGNTGYGAYCCNCCNTCNCCNGTNGAYATHAAYAAYACNCAYGAYGARYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN GGNTTYAARGTNGTNACNYTNYTNAAYYTNAAYAARAARGARATGYTNTCNGCNATHGAY AAYTTYAARGAYYTNGTNGGNGARGGNGTNTAYTGYGTNTTYTAYTTYTGYGGNCAYGGN TAYGARGCNTCNGGNCARTGYTAYYTNYTNCCNCCNGAYGCNCCNCARGGNTAYACNCAY GAYTAYAGYYTNTCNGCNGAYGTNATHYTNTTYAAYGTNYTNYTNCCNMGNAAYCCNMGN TTYTGYTGYATGATHYTNGAYATHTGY---MGNYTNMGNMGNAAYGGNCARCCNGARMGN YTNMGN---------CCNGCNAGYGCNGAYTAYATHATGTGYTAYGCNACNTGYTCNGGN GAYTTYGCNTAYGARCARCCNACNTCNGGNATHYTNGTNMGNCAYYTNAARGAYATHYTN YTNTCNAAYATHGGNGTNGARGCNGTNTTYCARGARYTNMGNAARAAYATH---AARGAY GAYCCNATHYTNMGNGAYAAY------------AAYMGNCARGCNCCNGARATHMGNACN GCNYTNTCNGAYCCNAAYATHTCNTTYCAYGAYYTNATHGAYTAYAARGGNTAYACNCAR TAYTAYAAYGAYMGNCARYTNCARTGGGARGARGCNCAYAAYYTNCCNCARTCNATHGAY AARGTNGTNAAYTTYCCNGGNTTYCARGTNAARYTNGARYTNGAYTTYCARGCNMGNTTY TCNAAYGCNYTNACNATHTTYACNACNATHGTNGAYGCNGGNCCNGCNAARTGYTGYAAR GCNTTYGTNAGYMGNATHCCNGCNGAYGTNGCNGGNAAR------GCNAARATHACNTGY ATHAAYGAYGAYGTNTTYATHAGYAARAAYMGNGTNACNYTNTAYGAYYTNCARMGNYTN CARTCNGAYATGMGNGTNGARATGYTNGTNACNTGYACNATGGARGAYGGNCARGARYTN AARGTNTCNTTYATHGARAAYYTNMGNAARCCNYTNGTNTCNGTNYTNCCN---TGGMGN GAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GAYMGNMGNCAR GCNTCNTGGYTNAAYGGNTTYATGATGTAYAGYMGNGTNCAYMGNAARAGYTTYATHMGN TCNAAYCCNGGNGTNCAYACNGCNCAYATHAGYAARYTNYTNGGNCARGCNTGGMGNCAR ATGACNTGYGAYGARCARCAYATHTAYMGNGARCAYGCNMGNATHTGYGCNCARGARYTN CARCARGTNYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATHTGGGCNCCNGAYAAYGARGGNGTNGTNTTY TGYGCNTGGGARCARGARMGNAAYMGNYTNGGNYTNMGNCAYTGYTGYCARMGNATGGGN GGNYTNTAYTAYYTNGAYYTNCARAARAGYTCNGTNGARMGNYTNTTYGARGARGGNMGN ACNCCNMGNTTYCCNMGNTTYAGYCCNGAYATGTCNAARYTNGTNTAYATHGAYTCNCCN ACNGGNGGNCCNCAYTAYMGNTGYGCNCARYTNGTNATGYTNGAYTGGGCNAGYAARAAR GARAARATHGTNGTNGARGTNGTNAARAGYGCNCCNGCNACNTCNTTYCARGGNATHTTY ACNGCNGGNATGAGYMGNGAYATHTGGTTYGARGAYGGNGTNCAYATHGCNTTYTCNACN GCNTGGMGNAGYAAYACNGTNGTNGTNATHGTNAAYACNGARACNGGNGCNGTNAARMGN YTNTCNMGNGGNGAYGAR------AGYYTNATHGTNYTNCARGTNCAYAARTCNAGYATH YTNATGTCNTGYTCNTCNTTYTGYACNCCNCCNTAYYTNTCNATHGCNCARYTNTCNGAY YTNGARAAYCCNGAYTCNGTNAARTGGATHAAYCCNGAYGGNATHCCNGAYAARYTNGAY YTNTTY---TCNTGGCARATGYTNTAYCAYACNCCNTCNGTNGAYMGNCCNGCNGCNAGY AAYGGNTTYGTNGAYTAYGARAGYATHYTNTGYYTNCCNCCNGCNGARAARGAYGGNTCN YTNCCNCCNYTNATHGTNTTYTCNCAYGGNGGNCCNCAYGGNGCNTTYGAYACNGGNTTY AARTCNGAYATHAAYTTYTTYTGYYTNTGYGGNTAYGCNGTNYTNATGATHAAYTAYMGN GGNTCNTGGGGNTTYGGNCARGAYGGNATHGARTCNYTNCCNGGNGCNATHGGNGAYYTN GAYGTNAARGAYGTNGARAGYGCNATGYTNACNGCNATHGCNAARGGNAARGTNGAYGGN AAYMGNGTNGTNGCNTTYGGNGGNTCNCAYGGNGGNTTYYTNACNACNCAYYTNATHGGN CARTAYCCNAARACNTTYAARGCNGCNTCNACNMGNAAYCCNGTNACNAAYYTNGTNTCN ATGGCNTCNACNACNGAYATHAARGAYTGGGTNTTYATHGARGCNGGNYTNCCNTTYAAY ATGGCNGCNYTNGCNGAYGAYAARATHYTNCCNACNYTNTGGCARTGYTCNCCNATHTCN CAYATHGAYCARGTNTCNCAYATHGARTAYTAYAARCARYTNCCNACNMGNTGYYTNACN TAYCCNAARAGYAAYCAYAGYYTNGCNGARGTNGAYGTNGARAGYGAYTCNYTNATHAAY ACNATHMGNTGGTTY--------------------------------------------- ------------------------------------------------------------ ------------------------GTNACNGAYGGNGTNTCNCCNTCNATGMGNGAYCAR YTNTCNTCNYTNTTYGAYGARGTNGTNACNGTNGAYATHYTNGAYAGYTCNGAYACNTGY AAYYTNGAYYTNYTNGGNMGNCCNGAYYTNAGYGTNACNTTYACNAARYTNCAYTGYTGG MGNYTNACNCARTAYAAYAARTGYGTNTTYYTNGAYGCNGAYACNYTNGCNYTNCARAAY GTNGAYGAYYTNTTYGAYMGNGARGARYTNTCNGCNGCNCCNGAYGCNGGNTGGCCNGAY TGYTTYAAYTCNGGNGTNTTYGTNTTYGTNCCNTCNGARAAYACNTAYAAYAAYYTNYTN CARYTNGCNGTNTCNCAYGGNTCNTTYGAYGGNGGNGAYCARGGNYTNYTNAAYYTNTAY TTYAGYGGNTGGGCNACNGARGAYATHMGNAARCAYYTNCCNTTYACNTAYAAYGTNGTN TCNCARGCNTTYTAYAGYTAYYTNCCNGCNTTYAAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TAYGCNTCNACNAAYAGYYTN GCNGAYGCNGCNGCNTAYTCNYTNYTNGGNTCNAAYMGNCAYMGNTGGGCNAARCARMGN ATHTGGGGNAGYYTNGGNATHGCNATHTTYGTNACNACNGCNGTNAGYATHAARCARAAY ACNGAYATHACNGCNATHTTYACNGTNTGYYTNATHYTNGCNGTNYTNGCNAGYYTNGTN GTNGTNTTYAARYTNAAYACNGCNAARATHAARACNTCNAAYYTNTCNAARGAYYTNAAY AGYATHYTNTCNAAYCCNACNTTYMGNYTNYTNYTNTGYAARYTNATHYTNTTYGGNTTY ATGACNGGNTCNGCNCARAAYTTYATGYTNTGGTTYGTNTAYTAYYTNGGNGGNTCNCCN YTNAAYYTNGCNATGGTNGTNGTNATHAAYAGYTTYTCNTCNGTNGTNGTNYTNMGNTTY ACNGGNATGATGYTNAARAARYTNGGNCCNCARTGGACNATGAGYATGGTNYTNGTNGCN CAYATHGTNMGNTAYYTNTGYACNTCNTTYGTNGARTCNCCNTGGATHYTNYTNGTNACN GARGTNATGCAYGGNYTNGTNTAYTCNACNYTNTGGGCNGCNGCNTCNGGNTCNACNAGY YTNATHGCNCCNTCNGGNACNCARGCNACNTGYCARAGYATHGCNGGNGCNGTNTAYTGG GAYYTNGGNMGNGGNYTNGGNAGYYTNGTNACNGGNCARYTNATHCARGTNYTNGGNCCN MGNTGGACNTTYMGNGCNTAYGCNGCNATHTGYGCNGTNGCNTTYGTNYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CAYTAYATHTAYCARGGNGAY ATHTAYTCNYTNCCNGAYAARCCNAAYAAYAAYAAYMGNAGYGARAAYGAYGARAAYCCN ATHATHTCNMGNATGAARGARATGGTNATHGARAARTCNMGNACNAAYAGYACNAARTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGATHGCNMGN---GAYGCNGARATHCARGCNYTNCARYTNTTYYTNTCN ATHTAYGGNAAYGAYYTNCCNCCNGAYGAYYTNGAYTTYTCNGAYYTNAAYTTYACNTCN ACNGARTTYGARCARYTNYTNGTNCARAAYYTNAARGAYATHCCNYTNTCNYTNGAYGGN ---YTNTCNGTNGAYTGYGAYCCNCCNGCNTGYTAY------GAYGTNCCNCARGARATH ACNMGNGGNGTNTCNCARCAYTCNYTNCARCARACNCAYCCNCARTCNCAYCAYGAYGAR TCNAAYYTNGCNGCNTTYTTYGAYAGYYTNTCNGGNTCNCAYGCNTCNAAYAAYGGNAGY GTNACNCCNACNTTYTCNGGNGGNAGYACNCCNCARGGNCCNTCNMGNGCNCCNTCNCCN GCNTGGAGYGARAGYAGYGGNAGYATGAGYACNAGYAGYGTNTCNGGNGTNTCNTGYCCN MGNAARYTNYTNCARGGNAGYTCNTCNATGGTNCCNMGNCAYATGMGNCCNTCNCAYAAR MGNGCNGARGTNAARMGNMGNGAYAARATHAARACNTCNYTNGAYGAYATHMGNGCNGCN GTNCCNAGYYTNCARGAYAARGGNAARYTNAGYGARTCNGCNATHYTNGARAARGCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNACNGTNMGNGTNAARGTNAARTTYACN AGYYTNAARMGNCCNGAYTCNGAYGCNTGYGCNAARCAYMGNGGNACNMGNTTYGCNMGN ACNGCNTCNGGNTAYGTNYTNGAYAAY------CCNCAYMGNTTYCARCCNACNGCNTGY ACNGTNCCNAAYTGYACNCAYGAYYTNGGNGTNAAYCAYTCNGTNTAYGGNGAYYTNAAR ATHTTYACNAAYAARCAYGTNGTNTTYGAYGARGARGARYTNAARAARACNACNATHGAY TTYTTYTAYAAYAGYGAYAARAARGGNATHGTNCARGARTAYGCNGTNCARYTNTTYTAY YTNAAYGCNAARTCNGAYAARGCNTTYATHAARGTNACNATHCAYGAYCARGAYATGTTY CARMGNYTNTAYCARYTNGAYTGYGAYMGNGCNTTYCCNAARTCNGTNATHGAYAARTGG GCNCCNTAYGCNATHYTNATHTCNCAYCCNCAYGGNATGCCNAARAARGTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNATHATHGAYAARYTNGGNCCNAARTTYGGNCAYCCNTCNATHGTNTTYAAR GCNAARCCNCCNGCNCAYCARTGYCCNCCNGCNAAYTCNTCNTCNAGYATHGCNTCNGCN YTNTCNAARGTNGAYCARGGNGAYGTNYTNGGNACNGGNGCNAAYCAYGTNYTNTCNACN TCNCAYYTNGARTCNMGNGARGCNATGTTYGARAAYCARCAYCAYAAYYTNYTNGARTAY YTNCCNAARGARGARTCNGARAARTCNATHATGGTNACNTTYCAYTTYYTNAAYCCNAGY CAYATGYTNCCNAGYGGNYTNGAYCAYGCNCAYCCNCARAAYAARCCNGTNTCNATHATG YTNTGGTGGTCNGGNACNCARCAYGTNTGYCAYTAYTCNYTNTTYAARACNGCN---AAR GAYYTNGARTTYAARCCNGARATHGTNTGGCCNTGYTCNAARACNATHACNTGYTCNGAY GTNAGYCCNTGYGGNTCNCAYATHGCNTTYGGNYTNGAYAAYGGNAAYYTNATGYTNTGG AAYTAYCARATNGGNYTNCCNAARGCNGTNYTNACNGTNTCNGGNAAYGGNGGNGTNMGN AGYGTNMGNTTYYTNGAYCCNAGYYTNTTYCCNTCNGAYCCNCCNCAYTAYCCNCCNTAY CCNGTNAAYTCNGCNACNTTYGTNYTNGCNGARTAYAAYGAYGGNACNCARGCNYTNTTY GAYACNTGYGAYGGNAGYCARCARATHCCNMGNATHATHGCNTCNAARCCNGARTAYGAR GARGAYAARCARACNYTNATHAARYTNATHCCNGARYTNCCNGAYYTNGTNTTYTAYGTN AARAARGAYGGNTCNATGTAYATHAARAAYATHGGNACNGGNGCNGCNYTNTGYGARGTN GTNYTNCCNGAYACNCAYAAYATHCARACNCCNTGGAAYCCNATHATHGCNYTNGGNAAY GARGGNCAYACNYTNTTYYTNAARGGNGARGGNAARCAYGTNAGYGARGARGGNGARGTN AGYGAYATHTCNTGYYTNTTYAARTTYAAYYTNMGNGARTAYTCNATHYTNGARGARTAY TGGACNMGNGTNAARGARACNTCNGAYYTNATHGTNTTYACNACNTGYGARCARMGNYTN GAYAAYYTNATGAARGARMGNYTNCARCARCARGCNATGMGNAARCCNMGNATGCARAAR CAYTGGGGNCARYTNMGNGGNGCNYTNGAYATHATHCARAAYGCNMGNGARGTNCCNGTN GARTCNYTNMGNYTNACN---GTNGGNCAYATHATGCARATGTAYGARGAYYTNGTNGGN YTNACNGARGTNAARTCNGCNCARTGYAAYGTNGTNGARGCNGARMGNGAYTTYYTNAAR GTNCARGAYGARMGNMGNTGYYTNCARCARGARYTNATGGARGTNCARACNGARGCNMGN TCNGTNGCNATGGARYTNGARAARACNCAYMGNACNGAYCCNAGYTAYATHGARYTNGTN AARAARGARCAYGGNATHYTNGTNGTNGARAARGARATGTCNAAYMGNGTNAARTAYYTN GAYMGNTCNGARMGNGAYYTNTTYTCNGTNYTNAGYATGMGNGTNMGNGARAGYCAYGAR AARGARMGNGCNMGNGCNGARMGNACNAARTAYTGGTCNATHGTNGGNTCNGTNATHGGN GCNATHATHGGNATHACNGGNTCNACNGTNAAYAAYCAYMGNMGNYTNMGNGARATGMGN TCNATHGTNCARGAYAGYGTNGARACN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNCCNGCNTAYGCNACNCCNCCNGCNTGYYTN CAYMGNGTNGGNYTNGARTCNAGYTCNACNGGNTCNTCNTTYCCNGCNGAYTTYACNAAR CCNGTNCCNYTNGCNGTNGTNTCNCCNGAYGGNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYGAYGAYGAYGAYGAR TAYTAYMGNGAYATHCCNGAYTAYCCNACNCARACNAARTGGGAYAAYGGNACNCCNACN ATHGGNAGYMGNGGNTAYAGYGGNCARGGNAARAAYATHGTNACNAARCAYGAYAARGTN YTNTGYGGNMGNMGNAAYGCNCARMGNYTNATGCARTTYCCNCCNGAYTTYGGNTGYGGN GAYGGNGARGGNATGGAYATGCARYTNCCNAAYCARGTNTAYAAYAARYTNAARCARCAY TCNYTNTCNGARGGNCARAARMGNCAYAARGTNYTNGAYAARAARGAYCAYTCNACNGCN ATHAARGCNGTNGAYGARAARACNMGNATHYTNATHTAYAARATGGTNAAYTCNGARTTY YTNACNTCNGTNGAYGGNGTNGTNAGYGARGGNAARGARGCNGTNGTNTTYAARGCNAAY GGNGGNAARAARGAYGAYGTNGARGTNCCNAARGAYGTNATHYTNAARGTNTAYAARACN TCNATGAAYGARTTYAARACNMGNCAYAARTAYGTNAGYGGNGAYTAYMGNYTNTCNAAR GAYGTNTTYAARAARTTYAAYCCNMGNAARATGATGMGNATHTGGGCNGARAARGARTAY YTNAAYYTNAARAARYTNMGNMGNAAYGGNATHMGNTGYCCNGCNCCNYTNGCNYTNAAR AARCAYATHYTNGCNATGACNTGYGTNGGNGGNGARAARCCNGCNCCNAARYTNMGNGAR GTNGTNYTNAGYACNGARGAYTCNCARGAYGCNTTYGARCARACNGTNGARYTNATGAAR GGNATGTAYCAYAARTGYAAYATGGTNCAYTCNGAYTTYTCNGCNTAYAAYYTNYTNTGG CAYGAYAARAARGTNTGGGTNATHGAYGTNGGNCARGCNGTNGAYMGNGAYAAYGCNAGY TCNTCNAAYTTYYTNYTNMGNGAYTGYAARAAYATHTGYGAYTTYTTYAARCARGCNGGN GTNTAYGGNGTNCCNTCNGCNGARGARYTNTTYAAYCARATHACNAAYTAYTCNTAYACN GGNAARGGNAARGTNTTYGARTCNCARGTNCARMGNTAYGARAARGARGARTAYGCNTTY GAYTAYTTYTTYGARYTNTCNGARTCNTCNMGNTCNCARGAYYTNGAYAGYGAYAGYAGY AGYGGNAGYGARGAYGAYGARGAYGTNGTNGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNTCNGARAARGAYGTN GGNATHACNGARTTYATGGGNGCNGAYGTNAARCCNTTYAGYGCNATHATHAARCARMGN TAYTCNGAYTTYATHGTNAAYGARATHGAYYTNGAYGGNAAYGARGTNCAYYTNAARTCN YTNACNCAYAAYGAYAARGARGARAARGARGARGARGARGARGARGARAARGARGAYGCN TCNAGYYTNYTNAGYGARGCNGAYMGNGARATHATHCARAARATGGTNAARGAYAARAAY AARTCNGAYACNCAYAAYATHCARGCNCCNGARGAYAARGCNYTNMGNACNAARATHCAY ATGGCNGTNAARAARAGYTTYTCNCARYTNGARACNATHACNGGNGARGAYGARCARGGN AAYAARGTNATHAARGTNACNTGGMGNAARGGNAARAAYMGNGAYGTNAAYMGNGAYGAR TGGCCNAARTCNAARAARTCNTGYMGNTAYGTNMGNTTYGTNYTNTAYAARGARAAYAAR GAYACNATGGAYGCNATHGGNYTNATHGCNAARAAYATHAARGTNAARGARAGYATGTTY CARTTYGCNGGNACNAARGAYAARMGNGCNAARACNACNCARGARATHACNGCNCAYMGN GTNCAYCCNAARAARYTNGTNGGNYTNAAYAARGTNYTNTGGAAYATGGGNYTNGGNGAY TTYMGNTAYGTNCARGARCCNYTNAARYTNGGNCARYTNTCNGGNAAYCAYTTYACNATH GTNYTNMGNAAYGTNGCNGCNGCNAARGAYACNGTNGAYACNGCNATGACNTCNYTNAAR GARAARGGNTTYATHAAYTAYTTYGGNATGCARMGNTTYGGNACNACNTCNATHCCNACN CAYACNATHGGNAGYGCNYTNYTNAARGGNGAYTGGCARAARGCNATHGAYYTNATHYTN GCNCCNMGNAAYGAYGTNCCNGTNAARGAYAARTTYCARCARAARTGGGCNGARACNAAR GAYGCNGCNGCNACNYTNGAYGTNACNCCNMGNTTYTGYGGNYTNGARMGNAAYATHYTN GARGCNYTNGTNAARAARGCNAARCCNTTYAAYGTNYTNGARAARYTNCCNMGNAAYACN MGNYTNYTNTAYYTNCAYAGYTAYCARTCNYTNGTNTGGAAYAARATGACNTCNMGNMGN YTNTCNGARYTNGGNCARGTNATHYTNCCNGGNGAYYTNGTNATG---MGNMGNAGYACN CAYTGYCAYACNGAYGARCCNGTNCCNACNAARCCNYTNGTNGTNACNGARGAYAAYATH AARGAYTAYACNYTNACNGAYGTNGTNYTNCCNYTNCCNGGNCAYGAYGTNATHTAYCCN AAYAAYCARGTNGGNGARTGGTAYAARGARYTNATGACNGCNGAYGGNYTNGAYATHAAY AAYATGAARMGNCCNCARAARGAYTAYTCNYTNCCNGGNGCNTAYMGNCAYGTNGCNGTN ATHCCNAARAGYGTNTGYTGGGGNCAYCAYMGNTAYAAYGAYTAYACNCARCCNYTNACN YTNAGYGAYTTYGAYGTNATHCARGGNGTNCARYTNAARCCN---GCNGARGAYGARGGN ACNYTNTCNGCNGTNGTNYTNMGNATGTCNYTNCCNTCNTCNTGYTAYGCNACNATGGCN YTNMGNGARGTNATGMGNATHGAYACNTCNAGYGGNCAYCARACNACNYTNAAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TGGAAYMGNYTNAARMGNAAR CCNAAYYTNTCNTCNTCNGAYGARYTNTGYGARGTNATHAAYGCNACNYTNGARTCNTAY ATHAARTCNTCNGAYAARACNGARYTNCARTAYGTNACNGARGTNTAYAARATHAAYACN GARAAYGTNGARGTNATHGAYGARAGYGARMGNGGNGAYATHAARATHACNGTNAARYTN TTYATHTGYAAYTCNCARCCNGCNTCNGTNGTNGCNGARTCNYTNAAYAARGTNYTNAAY GARYTNGARACNACNTTYGTNGARAAYYTNTTYYTNGCNATHTCNCCNAGYGTNTCNGAY GAYCARGARCCNGAR---CCNGTNTCNYTNACNACNATHCARAGYTAYTGGCARGCNATG GARGARYTNGTNGCNAARGAYAARGTNYTNCAYYTNGGNATHTGYGAYATGGGNAARGAR GGNYTNGARGCNYTNTAYAAYTGGGCNCARGTNAARCCNAGYGTNAAYCARGTNAAYYTN GARTCNTGYTGYGTNYTNCCNAARGAYYTNACNGARTAYGCNAARGGNGTNAAYATHCAR YTNYTNACNCAYAAYGAYMGNCCNGTNTTYATHACNAARGARTCNYTNCARGAYAARATH CARTCNGTNACNACNGARMGNGAYAGYGAYGCNTGGTCNCCNGARTGGGTNATHMGNTAY TCNGGNYTNATHAARTGYMGNGGNATHATHAARATGAARGGNTAYATHTTYCAYGCNATH MGNGAYAAYMGNAARMGNATHYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GGN GAYAAYCARGCNCAYGCNGAYAAYGAYGCNGCNGARMGNMGNAARAARMGNMGNAGYMGN TGGAAYACNGARAAYGAYGAYAARACNGTNATHCCNGGNATGCCNACNGTNYTNCCNGGN AAYYTNTCNGARACNCARCARMGNCARTAYGTNGTNCARYTNCARATHGARGARTTYACN MGNAARYTNMGNACNGGNGARYTNGGNATHCCNTCNAAYCCNGARCARMGNTCNCCNTCN CCNGARCCNATHTAYAAYAAYGARGGNAARMGNYTNAAYACNMGNGARTAYMGNACNMGN AARAARYTNGARGARGARMGNCAYMGNYTNATHCARGARGCNATGAARYTNAAYACNGAY TTYAARCCNCCNAGYGAYTAYAARCCNCCNATHATHMGNGTNAAYGAYAARGTNATGATH CCNCARGAYGARCAYCCNGARATHAAYTTYGTNGGNYTNYTNATHGGNCCNMGNGGNAAY ACNYTNAARACNYTNGARAARGAYACNGGNGCNAARATHATHATHMGNGGNAARGGNTCN GTNAARGAYGGNAARATHGGNMGNAARGAYGGNCARCCNYTNCCNGGNGARGAYGARCCN YTNCAYGCNTAYGTNACNGCNAAYAAYCCNGARAAYGTNAARAARGCNGTNGARCARATH AARGARATHATHAARCARGGNATHGARGTNCCNGARGGNCARAAYGAYYTNMGNMGNCAR CARYTNMGNGARYTNGCNYTNYTNAAYGGNACNYTNMGNGARAAYGAYGGNYTNCARAAR YTNMGNCARATHGCNGARAGYCARACNATHGTNACNAAYACNATHATHTGYACNATGTGY GGNGGNACNGGNCAYATHGCNCARGAYTGYAARCARAARMGNCCNGGNGAYACNTTYMGN ATGCARCARATGCARAAYCCNGCNGAYMGNGCNAARATGGAYAGYGARTAYATGTCNYTN ATGGCNGARYTNGGNGARGGNCCNGCNCCNTCNAARTCNGAYGGNGGNAAYTCNGGNCAR ---------------AAYCARCCNCCNTTYAAYMGNTCNATGYTNACNAAYCCNCCNCCN AAYCCNATGGCNATGAAYCARCCNTGGCARATG---CCN---CCNAAYMGNCCN------ ------------------------------CAYATGGGNAAYCARGGNCCNCCNCCNATG GGNATGCAYTCNGCNCCNCARCAR---------ATGGGNMGNATGCCNATGCCNYTNATG TCNTCNCARGGNCARGGNCCNCCNGGNATGCAR------------------CCNCARAAY TCNATGATGCCNCCNCARCARTCNATGGGNAAYATGCARCARCCNCCNCCNCCN------ ------------------------CCNCARCARCAR------------GTNMGNCCNTGG CAYCARACNGCN------------------------------ACNAGYCARTCNCARGGN ATGATGCCNCCNAAYTCNAAYTCNGGNYTNGGN---------ATHCCNCCNCCNCCNTCN TCNATGATGAGYGCNCCNCCNCCNCCNCCNAGYTCN---------CARGGNCAR---CAR GCNCCNCCNCCNTGGATGCARCARCARCARCAR---------GGNATGGGNCARCARCCN CCNCCNCCNCCNCCNCCN------------TCNTCNACNGCNCCNTGGCARCARGCNCAR CAYTCNCAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARCARYTNMGNAARTTYGTNGTNCAYGAYYTNTAYMGNGGNTGYMGNCARACNCCN GARMGNCAYGAYYTNACNGTNTTYCCNACNGTNAAYGAYYTNAARAAYCAYATHCAYCAR GCNYTNMGNGAYATHCARAAYGGNACNYTNGARYTNCARTCNGGNGTN------------ ---------------------------------------------CARGAYGAYGAYAAR CCNAARTCNACNYTNTGGTCNGGNACNGTNATGCCNGARACNGTNACNGTNACNYTNTCN CARAAYCCNGAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNCCNAAYAGYATHGCNTTYTCNACNTAY CCNACNTGYGAYYTNATHTCNAAYTCNAARYTNCCNGAYAAYTTYCCNGTNGTNAGYCAR GAYGAYGTNAGYGGNGCNGCNTCNTCNAARCAYTAYMGNMGNACNMGNTCNTCNYTNAGY CCNGAYACNCCNTAYCAYAAYGGNAARTCNTCNTGGGCNAGYCAYTCNGARMGNGARATH TAYMGNCARATHACNGCNGCNATGGARAGYGCNATGYTNAARACNCARGCNTAYYTNCCN AGYGTNCARTCNCAYCAYTCNGAYMGNYTNTCNCARCAYTCNAARACNTCNMGNAARTCN MGNAGYYTNGAYAAYATHYTNGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNTTYYTN TGYTAYCCNGCNGTNATHTAYYTNATGYTNTTYMGNGTNACNATHMGNCCNYTNTAYCAR AARCAYYTNGCNTGGCCNMGNCCNTCNTAYACNATGGAYMGNCCNGCNGGNCCNATGMGN ATGAARYTNAARGAYGAYGCNCCNYTNTGYCAYACNTGYACNYTNACNCCNGAYATHGTN MGNGARGARGTNGAYATHYTNAARAARGAYTTYAAYAGYMGNYTNAARCARATHYTNTTY AAYTCNYTNACNACNTCNTTYTAYGCNACNGGNGTNCCNGTNTGGTTYTCNCAR---AAY ACNYTNTAYTAYGAYTCNTGGTGGATGTGGCARCAYGTNTCNYTNACNTGGYTNAGYGCN YTNYTNATGYTNACNGCNCAYTTYYTNCCNCCNCAYTAYYTNCAYYTNYTNCAYAARAGY GCNMGNCAYYTNGGNMGNTGGCARMGNATGGARGCNMGNCAYGCNCAYGTNCCNTAYAAY GCNTGGTCNGARYTNCARGTNTGGCCNCARGGNGCNYTNGTNAARCAYGTNMGNGGNYTN TTYAARGCNGARGGNATHAAYGTNACNGCNGARCCNGGNAAYAAYYTNCAYAGYMGNTTY TTYATGYTNTTYCAYCCNCCNATGMGNGTNATGAAYTGGYTNGTNTTYYTNACNTGYYTN GTNATGGCNTAYCARGGNTTYMGNYTNYTNCARAGYTCNGARTGGAGYCAYATHATHTCN YTNGCNYTNYTNATGTTYTGYAAYTTYTAYACNYTNTTYAARYTNATGMGNGAYTGGTTY ATHATGGGNAARGTNTAYAARGARCAYGAYTAYGCNATGTCNAAYYTNGAYGAYAAYGAY GAYGARTTYGTNGAYGCNGCNGARYTNACNGARACNGARACNGARACNGARTCNCCNGAR GTNYTNGAYGAYYTNYTNAARGARYTNGAYGARAARGAYATHGARGARAAYATHGAYGAR YTNAARTCNAAYTAYATGCARYTNCAYGAYYTNATHAARMGNCAYCCNCAYGARGAYAAR ATHTAYTGGMGNATHTCNCARGCNGCNTAYYTNYTNGCNCARAARMGNAAYYTNGTNGAY GCNGARCARMGNMGN---------AARGARTTYATGGAYGARGCNMGNGARGCNGCNCAY ACNGCNGTNAARYTNGAYCCNCARTCNGGNGARGCNCAYMGNTGGATGGCNATHATHYTN GGNAGYGARACNCARCAYYTNCCNGTNGGNGARCARATHAARAAYGCNTTYATHATHMGN GARCAYATHGARAGYGCNYTNMGNYTNAARCCNAAYGAYTCNYTNGTNTAYCAYATGATG GGNMGNTGGTGYTAYTCNGCNTAYATGYTNACNTGGATGGARMGNAARYTNGCNTCNGCN YTNTTYGGNACNCCNCCNACNTCNACNYTNGARGARGCNYTNACNAAYTTYAARAARGCN GARGARYTNAAYCCNYTNTCNTCNATHTCNAAYCARYTNTAYYTNTCNAARTGYTAYATH GCNAARGGNAAYTAYAARACNGCNGTNCARCAYYTNCAYAAYGGNATGGCNATHAARCCN AARATHTCNGAYGAYYTNGARGCNCARGARGARGTNGCNGCNGAYYTNAARTAYTAYCAR TCNTAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TCNAGY YTNAGYCARACNCCNTAYYTNCCNACNCCNGGNCCNTCNTCNMGNGAYAAYGAYACNTAY TCNCAYTAYYTNMGNMGNYTNTCNYTNCCNTCNTCNAAYTGGCCNATGACNATHGAYCAR ATGTGGTAYAGYATHGAYATHGGNCCNATHCAYGTNATHAGYTAYTCNACNGARGTN--- CARGGNCARCARAARTAYGCNCARGCNCARCAYACNTGGYTNATHGARGAYYTNACNMGN GCNAARGCNAAYMGNAARAAYGTNCCNTGGATHGTNGCNTTYGGNAAYCARCCNATGTAY TGYACNAGYGARGAYCCNTCNCARATGTGYAAYCARGAYATHYTNCARGGNACNAARGAR YTNGARGAYYTNATGTAYACNTAYGGNGTNGARYTNGTNATHTCNTCNTCNCCNAAYGGN AAYATGGCNTCNTAYCCNATGTAYAARGGNGTNAARYTNGGNGAYGAYCAYGARAARCCN TTYGGNCCNACNCAYATHAGYATHGCNGCNGGNACNMGNTGGACNAGYAARTAYAAY--- ---ACNTCNGARGARGARTGGGTNTGYTAYCARGAYGAYGAYAARGCNCCNYTNACNTTY GGNMGNYTNTCNGTNCAYAAYTCNAGYMGNYTNCAYTAYGARATHGTNGCNTTYGARGGN GAYMGNGTNYTNCAYTCNTTYCAYATHGAYGTNAAYGARCAYCARGGNTTYTCNAARGAY CARYTNCCNGTNAAYYTNACNYTNAARATHGAYGARCARATHAARYTNGCNGGNGGNGAY CCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AAYGTNGCNGCNTCNTCNGGNGGNGGNYTNCCNGAYTTY YTNTCNGAY---GGNCCNYTNYTNGGNGARAAYCAYCAYTCNTCNAAYMGNCCNGTNGAY CARGGNMGNMGNGARGAY---------GAYYTNATGAAYCARATHCARATHYTNCARGAR GARAAYAGYAARYTNMGNAARGAYYTNTCNCARTCNAARCARAARTGYGAYGAYAARAAY CARMGNATHTCNCARYTNAARACNGAYYTNGARMGNCARAARAARAARGARGTNGARGAR ACNGCNGTNATGGARAARGCNGTNATGCARGTNGARGARAAYYTNGTNACNACNACNCAR MGNGCNGTNCARGCNGARTCNAGYGGNACNAARYTNAARCARGARGTNAARTCNYTNCAR GGNCARYTNMGNAGYYTNTCNGCNGARYTNCARGTNTAYCARAGYGGNGAYAGYGGNYTN AGYGAYATHMGNGARMGNACNAARTAYACNTCNGARCARYTNAARACNGCNGCNGARGTN GCNGARAARAAYYTNAARGAYYTNYTNYTNGGNGTNGAYAARATGAARYTNYTNTCNCAR GTNYTNTCNAGYTGGGARAARATHACNGARGTNAARCCNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MGNYTNAAYTCNTCNCAYTGGCCN GTNAAYCCNTAYGARGTNGCNMGNGCNYTNATHCCNAARGCNCAYMGNYTNTAYTAYAAR TGYTCNGARTTYCAYGARGAYTTYMGNTTYAGYYTNAGYTTYATHGARAAYTGYGTNGAR ATHCCNGCNTCNMGNTCNYTNTGYGARMGNYTNTGGCARTTYMGNAGYMGNYTNAARMGN AARAAYGGNACNATGMGNATGAGYAGYMGNGARYTNGCNGAYGGNATHGGNATHATGATH CARTTYGTNTCNYTNCCNTCNTTYGCNGTNAAYTCNCAYACNATHGARMGNYTNAARTCN YTNCARATHGAYGAYGAYGARGARGAYGARGGNTGYTGYGTNATG--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GAYGAYGGNCAR TCNAGYAARAAYAARGAYGTNGGNMGNTTYTAYAARYTNAARGCNGGNATGTTYYTNACN ACNGTNACNGGNTGYTCNGTNYTNGCNGGNTTYGGNYTNACNYTNGGNATGGCNAARAAR CAYGAYCCNAARAAYTTYGCNAARGGNGTNATHGGNTCNMGNGARYTNCCNGARAGYGGN GTNGCNYTNGCNACNMGNGCNYTNGGNMGNGCNACNYTNTAYTCNGTNACNGGNTTYGGN YTNGTNTGYTTYGCNGTNTGGAARATHATHGGNGCNCAYAAYATGGCNGARTTYMGNGAR AARGTNGGNAAYGCNYTNCCNMGNGTNAARMGNAARGARAGYACNGGNMGNAAYGARTTY GCNACNATHMGNGAYYTNTTYAAYTAYATHATHGAYGARGAYAARAARGCNAARGCNGGN AARGAYGAYAARGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------GARATHTCNATHTCNATHYTNCARAARMGNYTNGARAARCAYGGNYTN TCNAAYAGYGTNTAYACNCARGARACNGARYTNTTYGTNCCNGGNGCNTCNAARCARACN YTNGAYAAYYTNGTNAARGARAAYACNMGNYTNMGNACNYTNYTNAARCARGAYAAYGCN CAYTCNCCNAARAARCCNTCNGAYGARACNGARGARATHAARACNTCNYTNGARGAYGCN MGNATHGARATHGARCARYTNAARAAYAARYTNAARGAYGCNGAYGGNATHAARYTNAAY YTNGTNAARGARTAYGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TTYGAYAAYATHGAYAAYTGYCARTTYTGYAARAAY GCNGCNGAYAARATGTCNACNTTYGARTTYAGYAAYGTNACNMGNGTNAARGARTTYATH GARTCNATHAARYTNGCNTTYGTNCAYAAYYTNAAYAARYTNAARMGNTTYYTNAARCAR GCNGARYTNGAYCAYTAYGCNYTNTAYAGYGCNYTNTCNTTYYTNAARAARTGYGGNTGY GGNAAYYTNYTNYTNMGNTAYGTNAARYTNGAYGCNGGNTCNGAR--------------- ------------------------------------------AGYAGYATHAAYTGYCAY GGNTGY---------CARTAYGAYAARTGYGGNGAYGAYTAYGAYGTNCARAARTAYAGY GGN------AAYYTNGGNGAYTGYGGNGAYGGNATGTAYTGYGTNAARTAYAARACNATH GTNTGGATHCARGAYTCNGGNGARATHYTNGGNAAYTTYMGNAARTCNCAYGTNGTNACN MGNACNTGYGARTCNAARAARGGNAARAARGARGGNTGYACNGGNTGGCARAAYAAYGGN GGNYTNACNYTNAARTGYTGGTGYGGNCARGAYGGNTGYAAYAGYGGNACNTCNGCNAAR CCNGTNGCNGTNTCNATH------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYMGNTGYGARTCNGARAAR MGNGARTTYAAYAAYMGNYTNAARTCNYTNAAYCARAARCAYAGYYTNATGCARAGYCAR AAYACNGARATHGARGCNGAYTAYATGAARYTNAARCARGAYATGGARAAYYTNMGNGCN GARCAYATGCARACNGARAGYCARCAYGCNCARGARTAYCARACNYTNAARCARACNAAR GARAARGARATHTCNGAYYTNAAYGAYCARYTNTCNACNYTNAARCARGARAAYGARGAY YTNCAYAAYTCNATHACNACNYTNCARCARATGATHGARAAYYTNCARAAYGCNAARAAR TCNYTNCARGAYAARAAYGCNGARYTNCARCARTAYCARCARCARAARCARYTNGARYTN CARAARCARAAYGAYGARAAYGCNAARAARGCNGCNCARCARCARATGAARGTNGCNYTN CARAAYAAYAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYATHAARCCNGAYATHAARYTNYTNCARCARYTNGCN GCNAARAARTAYGCNGGN------------TCNGGNCCNAGYTCNTCNACNAARGGNMGN AGYTCNYTNAAYCCNGCNGTN------CARGARTCNTAYGCNATHAARYTNAARMGNYTN AARGGNACNATHAARGARTAYATHTTYATHAAYGGNGCNGTNTGYGAYGARGTNCARMGN ACNGARGARAARYTNGCNMGNGTNAARGARGARMGNMGNTTYYTNYTNMGNAARYTNYTN CARTTYCARTCNATHTCNGAYCCNACNGGNACNGCNCAYAARGCNGAYACNCCNGCNGCN ATGGTNMGNAGYYTNAARGCNGCNTAYGARAGYAAYAAYGAYGCNACNCCNCCNACNACN TCNAARGGNGGNAARGGNGTNAARMGNAARYTN------------------GCNTCNACN CCNACNCCNTCNTCNGCNGGNATHGCNGGNGGNGCNAGYAAYGCNGGNAGYTCNATHCCN TCNGARGGNMGNAARAARAARGGNCARGCNACNAARGAYGCNACNGAYTCNGTNCARGGN MGNCCNAARAARAGYAARTCNGGNGGNAARAARAGYATHCCNCCNYTNATGYTNGAYTCN YTNGGNMGNCCNATGATHCCNATGATGYTNGGNGARATHACNYTNCAYAGYATGGGNGAR ATHGTNACNGAYMGNAAYAGYTTYCAYTGYCARGARGCNATHTAYCCNGCNGGNTAYTGY ATHACNMGNGTNTTYGTNAGYYTNTGYCCNCCNGAYAAYMGNTGYYTNTAYACNTGYAAR ATHTCNGARGGNGARGAYGTNCCNYTNTTYGARATHGCNCCNGARGAYAAYTCNGAYATH GTNTTYAARGCNAGYACNCCNGTNGARTGYCAYMGNYTNYTNYTNCARGCNGTNAAYGAY GARMGNTCN---GARGTNGTNACNACNAAYACNAAYGGNYTNGAYTTYTTYGGNYTNTCN CAYTCNGTNATHCARAAYYTNATHCARTCNATHCCNGGNGCNMGNAARTGYTCNAARTAY AARTGGGTNAARTTYGARATHGAYAARTCNCARACNAAYGCNAAYTTYGCNATHGGNAAR AAYGAYCCNACNATHAGYTTYGARGCNTTYATGACNCAY--------------------- ------------------------------------------------------------ ------------ATGAAYTTYAAYATHGARTCNATHYTNGARGCNGGNGGNMGNYTNGGN AARYTNACNCARYTNGTNCARGGNAARGTNGTNACNATHGARACNCCNATGTGYACNYTN TTYACNAARGGNGGNAGYGCNCCNCAYYTNAGYYTNAGYATGYTNGARMGNATHAARTAY GCNCCNGARYTNGCNACNATGAGYATHAAYTCNTTYGTNGARCAYGTNGAYAGYATHAAR GGNAGYGGNAARMGNYTNGCNGAYTTYGCNTCNATGAARAAYAARATGGTNTTYTCNACN YTNCAYGAYGCNAGYYTNCCNYTNAAYACNGGNAARAAYGARAARTCNGGNATHGCNATH TGGGGNAARGGNGGNAARACNYTNYTNAAYCCNGCNACNTTYATGACNATHCARGAYACN YTNCARGCNGAYTGGGTNATGGCNYTNAGYGAYGGNGAYACNGAYAARAAYAGYACNGAY AARMGNAAYGGNAARGCNGTNGAYMGNACNYTNGAYTTYYTNGAYGARATHGTNTCNGCN TGGAARGARAGYGARGTNYTNAARAAYTCNAGYYTNYTNGGNGCNGTNGTNGGNGGNTTY AGYGARMGNCAYMGNATHMGNAGYGCNACNGARACNGCNACNMGNCCNGTNCAYGGNTTY YTNYTNGARGGNTTYCARAARGGNCAYGCNGARAARACNYTNTTYGAYGAYAAYTCNTTY ACNGAYATHYTNTCNAARACNYTNAGYCAYYTNCCNGARAAYAARCCNMGNATHATGGAR ACNGCNTGGTCNCCNYTNGAYATHATHCARGCNTTYAARYTNGGNATHGAYGTNTTYTCN AGYGCNTAYCCNCAYACNYTNACNGARAARGGNCARGCNATGACNACNGARTTYACNYTN CCNCCNGCNTCNTCNACNGARAAYYTNGARCARGARGGNAGYACNGCNAAYAARACNAAY TCN------GTNATHAAYYTNAAYGARAARAARTAYTTYGARGAYTTYGAYCCNGTNYTN GCNGGNTGYCARTGYTAYACNTGYMGNACNTTYACNMGNTCNTAYATHCAYCAYYTNYTN AAYACNTCNGARYTNYTNGCNTAYGTNYTNYTNACNATHCAYAAYTTYGARMGNTAYTTY YTNTTYTTYCAYACNYTNMGNCARACNATHAARGAYAAYMGNYTNGAYCARYTNGARCAR ATGATHMGNAARCAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYAGYGAR--------- ---------------------ATHTGGMGNCARMGNAAYTTYGGNTTYYTNTGYGCNGGN MGNTAYTCNGAYMGNAARNNNMGNGARTTYYTNGARMGNGTNTTYYTNCAYGCNGTNGAY TTYTTYYTNCCNCCNTAYCARTTYCARGTNMGNGTNGGNGGNYTNTAYYTNYTNTAYGCN ATHTAYGTNACNCARCCNGTNGCNCCNMGNGTNAARGTNMGNYTNACNACNAAYCARTGG AARGARACNGTNCARTTYYTNCARGARGCNAGYCAYCARAGYCAYYTNGAYGTNGTNTAY GTNTTYAAYMGNATGYTNGARGARGGNGCNTTYCAYTTYGTNTAYACNCCNATGGARATG TGYGARAARTCNACNAAYYTNGARMGNGAYGAYGAYGARATHAAYYTNGCNGAYGARATG AARGARGARMGNMGNGARATHAAYMGNYTNTTYAAYTAYGARTCNATGGARCARYTNTCN TAYYTNYTNGGNCAYTAYAAYCARATGAARATHAAYYTNGCNGGNCCNAARTCNGCNAAR CCNGAYAARTCNYTNGAYGTNGTNCARGGNTCNATGGTNGARGAYYTNATHTCNYTNYTN CARGAYTTYAARCAYAAYGTNACNAARATHTAYAARCAYGGNTCNTCNAAYCARTCNGGN CCNAGYACNTCNTCNCARGARATG------AGYATHTAYGARAARMGNCARGCNATHAAR AAYMGNYTNTAYGARGAYATGACNACN--------------------------------- ------------------------------------------------------------ ------MGN--------------------------------------------------- ------------------------------------------------------------ ------AARACNAARAARAAYAARCARGGNAGYATHAGYTTYGAYGTNATHYTNAARCCN GCNGCNCCN---TCNCCNMGNCCNTCNYTNCCNYTNTCNCCNMGNGAYAAYAARCARAAR GARYTNTCNGARGARCARATHGCNATGAARYTNAARAARGCNGARCARMGNMGNAGYYTN ATHGARCARGARAARATGGARCARYTNGCNAARGARMGNCARAARGCNATHGARGTNATH AAYAARGCNCARACNGARAGYGTNGARTTYTCNAARAARACNGARCARAARYTNMGNMGN TCNATGGARATHMGNMGNGARAAYMGNGARACNCARATHMGNGCNYTNCARGARMGNYTN MGNGARCAYTCNGTNMGNGTNCAYGAYGTNCARATGACNGGNATGGAYATGGTNAARGAR TTYGARGCNAARGCNGARCARAARYTNAAYCARAARATGGARACNTAYGARGARAAYMGN AARAGYCARYTNTGYTCNATGYTNCARAARYTNCARGARCAYGCNTTYCAYATHAAYGAR GTNTGYAAYGCNAGYGARAAYMGNGGNATGAAYACNGAYGARYTNCARGARCARYTNGTN CAYAARATGGARAAYGCNYTNAARAAYMGNGARGARCARYTNMGNYTNATHCARGAYMGN YTNGCNGARCAYGARAAYMGNATHAARGARGTNCARAARAARAARGGNATGGTNTCNTCN GGNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGTAYMGNCARCARTAYCARGGNGCNGARCCNCCNCCNTAYCAY CCNTCNTCNATHAARCARTGGGCNAGYAARGTNYTNAAYTAYTCNTCNCARTAYAAYTGY ACNGGNTGGTCNGCNAGYCARGTNGTNGGNCARCCNAARGTNTAYCCNMGNTAYGGNGAY ATHCARGGNTCNTGGGCNCARGGNAGYTTYGAYMGNCARGARTTYGTNGARATHGARTTY GAYGTNCCNGTNMGNCCNTCNAARATHAAYATHTAYGARACNTAYAAYCCNGGNGCNGTN GTNAARATHCARGGNMGNAAYGGNTCNGGNTCNTGGTCNAAYYTNTGGCARACNGAYMGN CCNGTNMGNYTNTCNGTNAGYMGNATHTTYTCNCCNCCNYTNACNGGNTCNATHCARAAR ATHAAYCARYTNMGNATHGARYTNGAYTGYTCNGTNACNMGNACNTGGTGYGARYTNGAY GCNGTNGARYTNGTNGGNATHMGNGAYGGNGCNGTNCCNCCNGTNGAYGAYACNCARTTY TTYGARGAYATGMGNATGYTNGTNAAYAGYGARTTYTTYAGYGAYGTNACNTTYAARYTN GARGGNAARAARGTNCAYGGNCAYAARGCNATHATHGCNGCNMGNTCNCCNTAYYTNGCN AARYTNYTNAARAARAGYAARGARGAYACNATHAARYTNGAYATHCCNTGYYTNGAYCAY AARGAYTTYATHGTNGCNTTYAARTTYATHTAYACNAAYMGNYTNCCNMGNGAYYTNTCN ACNTCNACNYTNGCNGCNYTNTGYAARGCNTCNTCNATHYTNGARATHCCNGARATGAAR ACNGCNTCNATGTAYAARYTNGTNGCNGGNYTNAARACNGAYAAYGTNGTNGCNATHYTN CAYCARACNGGNGAYGAYCCNTTYTTYGCNGARATHAARAGYYTNTGYATGGCNTTYATG GCNTCNCAYYTNAARGARATGTCNAARGARCCNTCNTTYGARAARYTNCCNCARAGYACN ATHGTNGCNGTNGTNCARGARGCNACNYTNTCNYTNCARYTNAAYGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GTN GTNTGGMGNGAYTGYCARCARYTNATHGARAAYTAYTGYCARGARGARTTYTCNAAYACN CARAARCARGTNTCNAAYMGNGCNAARAGYTTYATHACNCARCARMGNCARYTNYTNAAR AAYCAYYTNATGAARGAYTCNTTYATGGAYGARGARACNATGAARAGYYTNGTNTCNGGN CAYAARACNTCNAARGARAARGTNYTNTGYCAYMGNTGYAARMGNGARMGNTGYACNTGY GAYGARTGYACNATHACNCAYATGATHACNTGYGGNATHATHAAYACNGAYAARGGNACN ACNYTNCCNCCNCCNCCNAGYTCNTTYAAYTTYGCNYTNGAYCARGCNCARAAYGTNATG GAYATHACNCCNCCNTCNATGTCNAGYACNACNTCNAGYAGYGGNTCNGTNTCNCCNATH AAYGTNGARGAYAARATHACNGCNTGYGAYACNGARAARMGNGARGCNATGYTNTGYGAR GAYMGNMGNYTNGAYGAYATHGAYGGNAAYGCNGGNGAYGAYGARGAY---GAYGGNGTN GAYGAYGCNGAYAAYTGYGTNGAYCARCAYGGNAGYGAYGARCCNCAYAGYATGCAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGGGGNGGNATGMGNTCN TCNMGNACNCARGCNGTNCCNMGNCAYTCNYTNTTYGGNACNGCNYTNGARAAYGTNGAY MGNGARCARYTNAARGARATHGARGGNMGNTAYGTNCCNGARGGNYTNGTNAARAARAGY CCNAAYMGNTAYCCNYTNCCNTCNTAYATHAARGAYAAYATHCCNGGNMGNGARAAYGTN CARACNTCNCARAARMGNYTNGCNACNCARCARGAYGCNYTNTCNCARGCNGAYAAYGAR YTNAARACNAARCAYACNAARGCNTTYACNTTY---CARCCNGAYTCNAAYCCNAAYGCN AGYCAYACNGGNGTNCAYTCNAAYMGNCCNAAYTGGYTNACNGARAARGAYYTNGARCAY TCNAARGAYATHAAYATHYTNGGNYTNAAYGARCAYGGNAGYTAYAAYMGNGAYAARTAY GGNAARAARCCNCARGTNCAYAAYTAYAGYYTNATHGGNGAYGTNYTNGCNCCNAARATG GAYTTYAAYTCNGCNMGNAAYGTNGARGARGARAGYAARCCNCARGGNGTNAARACNAAY ATH------GCNTGGGGNCCNGGNMGNCAYYTNCCNCAYGARYTNATGGAR---AARCAR CARAARGARTCNAARTCNAARGCNAARAGYGTNATHGAYYTNCCNCCNAAYATHMGNCAY YTNTTYGGNAGYMGNGTNTGYGAYTCNYTNYTNTCNGAYCAYGCNATHGTNTCNYTNGCN YTNGARMGNCARAARTCNAARATGGGNCCNYTNMGNCCNTCNAARATHCARAAYATHGAR GGNYTNCCNGTNGAYYTNGGNAAYACNTAYGARAGYYTNGGNCAYACNACNMGNCAYAAY GTNTGYCCNGGNGTNAGYTCNGGNCAYYTNATHAGYMGNACNAARGAYGARTTYAAYGAY GARGTNCAYCARMGNMGNGTNCCNAAYACNGAYGARTTYMGNTAYCARMGNGAYGARYTN AGYACN---TGGTCNGARCAYAAYGTNYTNMGNGARMGNATGAARAARGCNTGG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARGAY TGYTAYGTNATGAARGAYCCNTTYTCNTCNAGYGGNGGNTTYGTNTCNGTNGGNGGNAAY TGYTCNCARTGYAARMGNACNGTNTGYATGGCNACNACNTGYAGYTTYTTYTAYACNACN MGNTTYTGYYTNAARTGYGCNGAYAARGARATHGTNGARTTYCCNACNGARYTNCAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARYTNAARGTNYTNCARATHTCNTTYCCNAAYCARAARTCNMGNTTYTGGACNACN ATHYTNGCNTCNGCNMGNCARGTNTTYTTYCCNMGNGAYCCNTGYTAYCCNAGYGTNATH YTNGTNGCNTCNAAYGAYAARCAYAARAARYTNACNTCNTGYATHGCNAARAARGTNGCN GCNATHTTYTCNGAYTCNCARGGNTCNCAYTCNACNTCNYTNGAYACNGAYATHGAYGAY ATHAARCAYTAYCCNTCNTCNAARCARAARGARGARYTNGAYGARAARYTNAAYYTNGCN TTYACNAARGCNGGNAARAARTCNATHGTNATHAGYAAYGTNCAYGCNYTNGARCCNCAR GCNGCNYTNYTNYTNCAYGGNTAYTGYGAYGGNGAYAAYGCNCCNTTYMGNGAYGTNATG ATHATHYTNACNTTYGTNGTN---------GAYGAYTCNGTNGTNATHTCNTCNGARMGN CARGTNGARCARAGYYTNACNCARATHTGGGARTCNGGN--------------------- ------------------------------------------------------------ ---------------ATGGCNACNAARACNGARAARTGGYTNTGYATHGARYTNGGNAAR YTNGGNATHGAYTCNACNGARGARAGYGCNMGNTAYATHYTNTCNATGGARACNAGYGAY GAYYTNGARGARTAYATGYTNGARYTNYTNGAYGGNTCNAGYACNAARGTNMGNTTYTTY ATHCARGARYTNAARGAYMGNTTYTCNTCNAARMGNGCNAGYAGYAAYATHCARGCNTAY MGNAARGAYAARGTNYTNGARCCNTGGGARGARAARTCNAARMGNAARAGYAARTCNACN CCNAAYCARATHAAYCARAAYGCNCARGCNACNACNAARAAYAAYTCN------TCNAGY CARCCNAGYGARAARAGYGTNTCNAAYTAYCARAAYAAYGTN---------TCNCARCAY TCNGGNGARATHGGNGTNGGNGCNAARAARAARACNAARTAYGTNCCNYTNTTYGGNAAR GARGGNCARGARAARTCNGTNGTNCARYTNCCNGGNMGNCAYMGNTGYGAYTGYCARGCN TCNAARCAYMGNYTNGTNAAYAAYTGYGTNCARTGYGGNMGNATHGTNTGYTCNCARGAR GGNTCNGGNCCNTGYATHTTYTGYGGNACNYTNGTNTGYAGYCCNGARGARCARGARGTN YTNGARMGNGGNTCNMGNAARGCNGARMGNYTNMGNGARCARYTNATGAAR---GGNGGN AAYAARAARYTNAAYGGNYTNAGYGARACNGGNCARTCNYTNYTNCCNATHGGN---TTY AAYGAYCARTCNMGNGAYGAYAARGCNYTNAARCAYMGNGAYAARYTNYTNGARTAYGAY AARACNAGYGTNMGNMGNACNCARGTNATHGAYGAYGARTGYGAYTAYTAYGCNACNGAY TCNAAYMGNTGGYTNAARAARGARGARMGNGARAARYTNMGNAARMGNGARGARGARYTN MGNCARTCNMGNTTYGGNTCNMGNMGNGAYMGNAARATHACNTTYGAYATHGCNGGNMGN AAYGTNCARGTNYTNGAYGCNGAYGARGAYTCNAGYAARACNATGTAYGAYAARGARGAY GCNGTNATHCARGAYGTNCAYTTYGGNAARTCNATHAAYAGYGTNCARCARTCN---AGY YTNGCNAAYCCNTCNTAYGARTTYGARCCNAARTTYYTNYTNGARAGYGARCCNGTNGAR TGGGGNCCNTCN------AARCCNATHTCNAAYAAYCAYYTNAAYCCNCARGCNATGTCN AARMGNATHCARGAYMGNGARYTNCARGARATGAGYGAYGARGGNATGTGYYTNAGYATG CAYCARCCNTGGGCNTCNYTNYTNATHTGYGGNATHAARATGCAYGARGGNMGNTCNTGG TAYTCNCARCAYMGNGGNMGNYTNTGGATHGCNGCNACNGCNAARATHCCNGAYAARGAR GARATHATGGAYYTNGARCARTTYTAYAARAAYTAYTTYAARGGNTCNCARYTNAAYTTY CCNAARGAYTAYCCNAAYGGNTGYYTNYTNGGNTGYGTNAAYGTNGAYGAYTGYYTNGAR CARGGNCARTAYMGNGARAARTAYCCNAAYGGNGAYTCNACNTCNCCNTAYGTNTTYATH TGYTCNAAYCCNTCNCARYTNYTNYTNAARTTYCCNATGAARGGNAARCAYAARATHTAY AARYTNGAYGCNCAYATHCAYCARGCNGCNAARAARGGNYTNMGNTGGAARGCNMGNTGY AARYTNTGGGARAAYAARGARGGNAAYYTNTAYTCNTGYTCNGGNACNGCNCCNGCNCCN TCNAARAAYTTYGTNCARGTNGTNGTNACNGAYATHGARGTNATHTTYMGNGTNTGGAAR ATHATGCCNCCNACNMGNTCNGARTCNAAYGCNGCNCCNACNCARACNMGNTGYCCNTAY GGNGARTTYYTNGARGAYACNMGNYTNMGNGGNGARATHGARMGNACNYTNGGNAARAAY GARYTNMGNTTYYTNGAYMGNYTNGTNGARAARCARATHAAYTTYATHGTNMGNYTNCCN MGNAAYYTNATHYTNAARGTNYTNTTYTAYYTNGAYYTNGTNTCNATHGCNAARYTNAGY ATGACNTGYAARTAYTTYAARGARYTNTGYTCNTGYGAYGCNYTNTGGTCNAARATHTAY ATGGARACNACNAARAARGCNATHACNCARGARYTNYTNATGGTNGTNGAYCARAARGGN TGGAARGARGTNTTYTTYATGAAYAARYTNCARYTNCARATGCARATGMGNMGN---GTN GGNGARCCNTCNAARGARTCNMGNTTYTTYTAYGGNAAYAARTTY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNGCNTGGCCNYTNGTNAAYAAYGAYTAYYTNATHGTNCARGTNACN AAYAAYCARATHGARGGNAAYCCNGAYGCNACNGCNACNAGYAARYTNACNGTNATHGTN AARGGNAAYCCNGARTGYACNTCNAARAAYTTYCARACNTAYCARGCNCARACNAAYGAY YTNCCNGGNGCNTTYGARGAYGGNCAYGTNACNTAYGGNCCNTAYGGNAGYGTNGARYTN ATHGARGTNGAYCCNGGNAARCAYATHGARYTNCAYATHMGNTAYATHGARACNGTNGTN GTNATHMGNCARATHGGNMGNTAYTTYACNTTYTCNATHAARATGCCNGARGARYTNATH AAY---------TCNAAYAGYYTNCARYTNTGYGCNMGNGGNTGYCCNAAYTCNGARYTN ATHAAYTAYCARAARTAYYTNGCNGAYMGNAARTCNMGNGARGAYGCNGARGTNGTNTGY MGNGARGCNAARYTNGTNGGNTTYTAYTTYGAYTCNTGYGTNTTYGAYYTNATGGCNACN GGNGAYGARAAYTTYACNYTNTCNGCNATHAGYTCNYTNCARGAYGTNYTNAARYTNCAR CCNTCNGARTCNAARTCNATHGGNAAYMGNACNACNYTNCARACNTAYGAYAARCARTAY GCNGGNGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARGAY GARGAYACNGTNCCNYTNGAYTCNATHATHGGNYTNATGAGYGTNGGNYTNYTNTGGAAR AGYTAYYTNATHTCNTTYYTNTTYACNTTYGCNATGGCNTTYACNTTYTCNYTNATHAAR ATHTTYCAYACNGARMGNYTNGARYTNCCNGTNGTNAGYCARATGGARTAYTCNAGYGAR AARACNYTNCCNGAYGCNYTNGCNTGYACNTAYTCNCCNYTNYTNCARCAYYTNGCNTAY TAYGAYYTNGCNAGYYTNAGYAARTAYGTNTCNCARMGNATHGARGAYYTNYTNAGYYTN AGYCARCCNGGNGGNCAYCCNAARGTNTGGATGCARGTNAGYGGNTCNGCNYTNTCNACN ATHCARGARYTNACNAAYCARGTNMGNGARGARAAYTGGTCNATHATGTCNMGNGTNCCN ATHAGYCARCAYAAYGGNATGGCNAAYGGNAAYGGNTCNTCNGGNGAYMGNTTYGARTCN TCNYTNGTNTAYMGNGGNGARGTNAAYTCNGAYGGNTCNCARACNGAYATHCCNMGNAGY GAYGCNGTNGCNAARCCNAGYATGTCNCARYTNGTNGTNAARYTNTCNTCNYTNCCNATH YTNTCNCAYYTNYTNGTNCARAAYCCNGAYATHAGYAGYMGNMGNYTNTTYGCNGCNTGY CARATHCAYATHTGGGCNGTNGARAGYYTNTCNCAYATHGCNGTNMGNGCNTAYACNGAR GAYMGNTAYGGNGTNGTNCARAGYTCNYTNCCNATHATHTTYATGTCNYTNTTYGARYTN TAYGARTGYATGGARAARCAYTTYAARYTNAGYACNTCNGCNMGNMGNTCNAAYGGNTCN ATHCAYTCNTCNACNGAYAGYGTNAAYMGNTAYAARYTNCAYGCNACNYTNAARTCNTCN YTNTAYMGNATGGTNGAYACNTAYAARGAYCAYYTNGARGAYATHAARYTNAARCCNGAR GARATHAARAARYTNGGNTCNTTYATHCARTAYTGGYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNGGNTTYATHATHAAYMGNTGGGCNGAYTGGAARYTNMGNTCNYTNMGNCAY AARAARGGN------------------AGYAARGGNTAYTAYATHCCNTAYGGNGGNYTN TTYAAYYTNGTNGTNAAYCCNAAYTAYTTYGGNGARYTNGTNCARTGGATHGGN------ ------------------------------------------------------------ ------------------------TGGACNATHGCNACNTTY---------------TCN YTNTCNGGNYTNGTNTGGGCNYTNTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GAYGARGGNATHTCNGGNACNTCNCCNGCNCARGAYGARTTYGTNAGYGAY GCNTTYGARGGNAGYGGNGTNACNGARGARGAYATHMGNMGNGARATGGARCARATHMGN GTNGARGGNACNAARGCNGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARAARCARTTYGARAARGGNAGYGTNGAYAARTTYMGNTTY AGYATHAARGAYATHGGNACNATHCARTCNYTNMGNGTNGARCAYGAYGGNMGNGGNATH GCNGCNGGNTGGTTYYTNGAYMGNATHATHYTNCARAAYGTNCAYCAYCCNAAYGCNATH TTYTAYTTYYTNYTNAAYGGNTGGYTNGCNMGNGAYGTNGGNGAYGGNCARYTNTGGMGN GAYATHCCNGCNAARAARAARYTNGTNAARGARGTNATHGGNGGNAARCCNGTNAAYTAY CARGTNACNGTNAARACNGGNGAYGTNAARTAYGCNGGNACNGAYGCNAAYGTNTTYATH ATHATHCARGGNAARAARGGNATHACNAARAARYTNCCNATGGAYGAYTCNAARGAYAAY TTYGARMGNGGNATGACNGARGTNTTYGARYTNAAYACNGTNGAYGTNGGNCCNATHCAR CARATHCAYATHGGNCAYGAYAAYGCNGGNCCNGGNGCNGGNTGGTAYTGYGARGAYATH ACNATHAARAARTTYYTNCAYCAYGARGAYATHGTNGTNTTYYTNAARGAYYTNAARAAR AARMGNAARCCNAARGAYCARAARMGNAARMGNYTNTCNGARAARYTNAARCARAAYGCN GARMGNGAYGTNGAYTCNGAYAARGARGAYYTNGAYTCNGARGARGAYCARACNGAYGAR GARAAYGARGARTAYMGNGAYGTNTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGCCNYTNTTYMGNATHGARACNAAYYTNACNAARAGYGARATHCCN GARAARTTYYTNCARGARGCNACNGAYYTNYTNTCNTCNGARYTNGGNAARCCNGCNTCN TAYATHTGYATHCARGTNTGYCCNGAYCARGTNATGAGYTTYGGNGGNTCNAARGARCCN TGYGCNAAYATHACNYTNAAYTGYATHGGNGTNGTNGGNCCNGAYAARAAYMGNAARGTN GCNCCNGTNYTNTCNAARTTYATHGARCARCAYYTNGGNATHAARCARGARMGNTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CCNGARAAYAARCCNAGYACNGGNATGTCNGARGGNYTN GTNATGGCNTGGGARYTNTAYGGNAAYGARAARGCNGCNATHGCNTTYGTNGTNAAYCAR MGNGARMGNAAYGGNCCNGAYCARMGNGCNATGGARTTYAAYGTNTAYGARMGNAAYCCN AARATHMGNTGYGTNTTYACNACNATGYTNGCNTTYGCNGARMGNGGNGTNYTNGAYGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GGNTGGCAYGGNGTNAAYTGYTCNACN CCNTGYTTYAAYGGNTTYTAYGGNCARAAYTGYAGYAAYMGNTGYYTNTGYGGNAAYTAY GGNAAYTGYAAYACNATHAAYGGNGARTGYCAYTGYCAYCCNGGNTAYAARGGNGARTTY TGYCAYGARCAYTGYMGNTAYGGNTTYTTYGGNCARAAYTGYYTNCARGTNTGYTAYTGY GGNGAYAGYTGYTTYTGYGAYCAYGTNACNGGNAGYTGYAAYAAYTCNGAYATHCARTCN GAYTAYATHAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ACNATHGARTGYYTNYTNGCNAAYGTNCCN GGNYTNAARGARAAYYTNGARAARGGNATHGARTGYATHGARTAYGGNTGYGGNAAYGCN TAYCAYTTYTCNGTNYTNGCNTCNMGNTTYCCNAAYAGYAAYTTYACNGCNACNGARGTN TCNGCNGAYYTNYTNGARCCNATHAARAARMGNTAYTCNCAYATHCCNAAYYTNAARTTY GAYGTNGTNGAYYTNAAYAARATHTCNGAYYTNCAYTCNAAYAARTAYCAYTGGATHTAY GTNAAYGAYGTNATHCAYGAYYTNCCNCAYCCNGTNGARGCNATGAARGARATHAARAAR ACNYTNAARAARCCNGAYGGNGTNTTYACNTAYGTNGAYAARGCNGGNAGYGGNAGYCAR CARAARGAYGTNGGNGAYYTNGTNGCNGCNTTYAAYTAYGTNACNGCNACNTTYGTNTGY ATHCCNGARAGYTAYCARATGGARGAYGGNGARGCNCAYGGNGCNTCNATHGGNAARGAY ACNAAYGARGGNTTYGCNATHGCNGCNGGNTTYAARACNACNACNATHATGGTNGGNATG GGNAAYGGNYTNTAYATHGCNAAR------------------------------------ ------------------------------------------GCNGCNTCNTTYCARGAR GCNCCNCCNTCNTAYGAYTCNYTNTTYGGNAARGTNAARGCNTGYAARCARGARTCNTCN GGNATHYTNGAYTTYTTYAARAAYTTYYTNATHATHATHYTNTCNACNATHGGNGTNACN ATHYTNATHGGNATHTTYATGGCNGTNCCNGTNTCNATGATHATHATGGGNGCNGTNTAY AARGAYGAYTGYCCNGCNGARMGNATGATHCCNATHTAYYTNATHGTNGCNGGNAGYTTY GGNTGYGCNAARAAYYTNTGGAGYYTNGTNAAYMGNTGYMGNAARACNGARGARGARMGN CARGARGAYCARAARAARGTNAAYCCNYTNGARAGYATHGTNAAYTGYTTYYTNTTYGCN TGGTTYATHGCNGGNTGYGTNTAYATHTAYMGNACN---AARGAYGAYTTYCARTCNAGY AARCCNGARGAYTCNGAYTAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNGARGGNMGNGAYGTNYTNAGYYTNAARMGNYTNMGNMGNGARGAR ATHAARCARATHYTNTGGACNGCNMGNGAYYTNAARACNMGNATHAGYGTNAAYGGNGAR ATHTAYCARCCNYTNGCNGGNMGNACNGCNGTNATGYTNTTYAARGARGAYAAYTCNGTN AARAARGTNTCNATGGARYTNGGNYTNTCNAARYTNGGNGGNCARGCNGTNTAYTGYGGN CCNATGGAYATHGAYGTNTCNGGNAGYGCN------AARGAYACNGCNMGNGARTTYTCN GGNGCNACNGAYTGYATHYTNGCNAGYGGNTTYATGCARACNTCNGTNGAYTGYYTNGCN AAYGARTCNTCNACNCCNGTNGTNGCNGGNCAYACNGAYGARGARTAYCCNYTNCARGCN YTNGCNTAYYTNYTNACNYTNCARGARCAYTTYAAYTAYYTNATGGGNTGYAARGTNGCN TGGATHGGNGAYGGNAAYGCNGTNYTNAAYTCNYTNATGTAYGGNTGYGCNAARYTNGGN ATGGAYYTNGGNATHGCNACNCCNATHGGNCAYGARCCNAAYACNGARYTNATGYTNGAR GCNATHAARATHGCNGGNAGYACNTCNGCNTCNATHCARTTYAGYAAYAARCCNYTNGAY GCNGTNTAYMGNGCNGAYGCNATHATHACNGAYCCNTGG---------------GAYGAY GAYATGAAYCARGCNMGNGAYAARTCNTTYCARGGNTTYGARGTNAAYMGNAARATGYTN AARGARGCNGGNGGNAGYTGGGTNACNYTNCAYMGNYTNCCNMGNCARCAYGGNGARATG ACNGAYGAYYTNTTYTAYGGNAAYGARTCNYTNGTNTGGCARGCNGCNGARAAYMGNATG TGGGTNAGYATGGCNGTNYTNYTNAAYYTNATHACNGCNTAYACNCCNTCNATHCCNATG CCNAARTTYGTNAARGGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNAARATGATHTCNTCNGGNMGNACNGCNMGNYTNGARGGNGARATH TCNYTNCAYAARGCNYTNGTNGCNGARATGAARAARAAYCARAARGARYTNGAYGARTTY GTNGGNGARYTNGARGARGAYGTNGARGGNATGCARGGNYTNATHYTNATGYTNCARCAR CARYTNAARGARGCNMGNGARCARATHACNMGNYTNCARCAYGARAAYGARCARYTNMGN ACNYTNCARTCNCCNTCNGARYTNGAYCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARGAYGAY------TCNTCNGAR GAYGARACNGGNACNTGGATHCARTGYTCNGTNCAYCAYTGYGGNAARTGGMGNTAYGTN GARAGYATHATHGAYCCNATHCARGTNCCNGAYTAYTGGGAYTGYACNATGAAYCCNGAY AARGTNCAYAAYAGYTGYGAYGCNGCNGARGTNGARTAYGAYGARAGYGARCAYATHYTN ACNMGNTTYACNYTNGGNTCNGTNGTNTGGGCNAARATGGAYGGNTTYCCNTGG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TCNGAYYTNGARGAYTTYGTNYTNMGNCCNGCNCCNCARGGNGTNACN ATGAARTGYMGNATHACNMGNGAYAARMGNGGNGTNGAYMGNAAYATHTAYCCNACNTAY TTYYTNCAYYTNGARYTNGAYAAYGGNMGNAARGTNTTYYTNYTNGCNGGNMGNAARMGN AARAARAGYGCNACNTCNAAYTAYYTNATHTCNACNGAYCCNACNGAYYTNACNMGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG GCNTCNTCNTCNTCNTGGGARGTNGTNAGYAAR---AARAARAGYAARGGNGARTCN--- AAYYTNTCNCCNAAYAARGARAARGARYTNTTYGAYAAYATGCCNMGNATHGCNMGNACN GAYCCNGTNCARYTNGAYGAYACNGTNTAYTCNGCNTTYATGGGNAARGARAAYAARAAR CCNTCNAAY---AAYAAYGCNAARGCNGAYGTNAARCARAAYGGNACNAARAAR------ AAYGAYAARAARAARAARCCNGAR---GARCAYAARAARAARCARAARYTNGTNGAYYTN AAYGTNGCNYTNTCNTCNYTNGAYGCNAARGAYYTNGGNGGNATGYTNACNCARTCNGAR GCNTAYTTYCCNGAYCAYCCNGTNGTNTGGYTNAARGAYYTNGCNTCNTAYYTNAAYATH AARYTNGARAAYACNMGNGAYAAYGAYCCNATHTAYAARGGNAARTCNGTNAAYTAYCCN YTNGAYGCNGTNTCNAAYGCNTGYTCNAARGTNYTNCAYTCNTTYATGAARAARTTYTCN AARCARACNYTNGAYAAYGTNTTYTAYTAYGGNATHCARACNATGTTYCARGAYTCNGCN AARGGNATHCCNGTNCAYGGNTAYMGNYTNTTYYTNCARYTNYTNTCNCAYGCNAARCCN GAYATHATHGCNGARAAYYTNCCNCARTAYYTNGARYTNYTNMGNACNCAYCARAAYAAY CCNTCNAARTGYYTNAGYYTNYTNTGGGTNTTYGGNCARTGYGGNTTYAARAAYTTYAAY TGYGGNYTNAARGTNTGGYTNGAYYTNATGYTNCCNGCNYTNGARGTNMGNCARGCNGCN CAYTAYCCNGTNGARTAYYTNGARGCNYTNATHAARTCNAAYAARAARTCNACNAARAAR ------------AGYTAYGGNYTNGTNACNYTNMGNGARTAYTTYCARGTNYTNGAYGTN TTYTTYTGYCCNAARTTYACNYTNGCNAAYGAYYTNAARAAYMGNYTNCAYYTNYTNTAY CCNTTYATHAARACNYTNGCNTTYGGNGARACNCCNTCNCAYAAYYTNMGNACNTTYTTY CCNTCNTAYYTNAGYMGNTTYAGYAGYACNAAYTCNAARGCNATGAARGARGARYTNYTN GAYTGYYTNACNCAYTGYYTNATHACNGAYAARCARTCNTTYAGYGTNTGGTGYCARYTN TAYACNAARAAYYTNACNGCNTCNGCNTAYYTNYTNTGYCAYATHGAYGARAARTGGTCN ACNYTNTCNGGNAARYTNGAYAARAARATHYTNACNGARACNYTNMGNTCNTTYACNGTN ACNAAYGARGARYTNGARYTNCARTAYAARGGNAARYTNGAYGGNYTNAARYTNTCNCAR AAYGCNACNAARGARYTNATGGTNAARYTNAAYGGNACNTCNTTYCCNTGGAGYYTNYTN GTNTTYTTYATGGTNTCNATHTTYGCNGCNATHGTNATHTAYGAYATHACNTCNAGYTCN ACNTTYMGNTCNTCNAARTCNATGCARTTYYTNGARCAYTAYGGNATHYTNTCNYTNYTN GAYAARACNTAYCARGGNATHAAYAAYGTNATHGTNYTNTCNGTNCARTGGYTNAARACN AAYTTYCCNATHATHTTYGCNTCNGTNMGNGAYACNGTNGTNCCNTTYGTNACNACNACN TGGAARAAYTCNAARGAYTTYGTNYTNAAYGCNGARGTNGARTCNMGNCCNTAYMGNGCN YTNYTNGTNGCNAARGTNATHCARYTNTAYCAYTGGGTNTAYGAYYTNTCNCCNGARTTY TGGYTNMGNTGYGARGARYTNYTNTCNYTNTCNTGGGARTTYTCNAARGAYTAYTCNTAY MGNATHTGGGTNGTNYTNGTNGAYYTNYTNGTNCARGCNGAYCAYTGGYTNACNGARCAY GTNTTYACNGGNTCNYTNTCNAARGARGCNATHAARGAYACNGCNYTNMGNGGNGTNGAR CAYTTYAARAAYAGYACNTCNYTNYTNYTNTCNTGGGAYGAYTTYTTYCARGCNTTYATH CAYTCNYTNMGNGCNACNTGYTTYCARTTYYTNCAYTTYMGNGAYCAYGTNAAYATHMGN GGNTTYATHTCNGTNGARGTNGAYGGNACNGGNCARMGNCAYATGGTNYTNGCNGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GGNMGNGCNTAYTTYYTNTAYAARCCNAARGGNAARAARCARACNATHGGNGTN ACNTCNGARATGGCNYTNCARAARTTYAARTCNGGNYTNTCNGAYMGNAAYACNACNTTY ATHTAYCAYTGYCAYAAYCAYTAYTTYACNCCNATHGGNTAYGARGAYTCNCCNCARTAY CCNTCNGARGCNTAYAGYAAYAARYTNACNCCNGARACNACNGARAARACNTGGATHTTY GTNGGNGAYACNAGYMGNMGNTAYGTNCCNATHCAYTGYAARAGYTGGGARGARATHTGY YTNGAYYTNAAYTGYGARAGYCCNGAYTAYTTYAAYATHMGNGARTCNTGGAARGGNGTN AARCARMGNGGNGTN---AARAARACNGGNAAYAAYYTNCAYTGYATHATGTGYTAYCAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYGARAARATHGCNCARYTNGAYATHGCNGARTCNGAR ACNAARAARAAYYTNACNAARGCNTGYTCNAAYAARYTNTCNGTNGTNCARAARYTNAAR TCNGARGARGCNTCNYTNTAYTCNCARATHTCNTCNCAYCARAARACNATHAAYYTNYTN CARCAYGARYTNGAYCAYYTNGCNAARGARAARGCNATGYTNGAYAAYGTNTCNAAYAAY GAYACNGAY---GCN---AARGTNAAYCARYTNGARGCNGARGARYTNATGTTYMGNAAR TAYYTNGGNATGGARATHMGNAARGTNAARGGNGGNTGYYTNCARATHGCNTTYAGYCAR ATHGAYCARAARCARCCNAAYTCNYTNTTYYTNTTYTCNYTNCARATHGAYGARAAYMGN CARTAYATHGTNACNGAYTGYAARCCNAAYATHCCNGAYYTNGARACNATHACNAAYGAR YTNAAYAAYACNAAYAAYTTYCARAARTTYGTNMGNACNATGMGNAARAARTTYAARGAY TCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNAARMGNMGNTAYAGYGAYGTNYTNAAR---GAYCCNTAYAARGGNCCNCARGAR TTYATGGARGCNGGNGTNMGNGGNTTYYTNATHYTNTGYCARCCNGAYMGNGARGARCAY GCNATHGAYGARTCNATHAARATHYTNMGNAARACNTGYYTNAARYTNTAYGGNGGNATG AARCCNCCNAARGARGCNACNTTYGCN------AARGGNTAYGTNATGTGYGAYTTYATG MGNYTNGAYGAYGTNCARACNTTYCCNCAYCCNGAYGCNGARAARGARAARCCNGTNGAR GARGARCCNGCNAARGARACNGAR------------------------------------ ------------GARGCNGCNGCNGARGTNACNCCNGCNGARGCNGARGGNGARGCNAAR ACNGARGAYGCNGTNGCNGARGGNGARGARACNAARACNGARGARGTNGARAAR------ ---------------------------------CCNCARGARGARGARAARGGNAARGAR GAYGTNCCNAAR------------------------------------------------ ---------------------------------------------------AARCCNMGN MGNGAYGGNGGNMGNCAYMGNYTNATGYTNGCNACNMGNAARTTYCARGGNTAYMGNACN GARYTNMGNAAYATGATGTTYGTNAARTCNGAYATHGCNGAYCCNGTNGARGTNYTNACN GARGCNTTYGAYYTNATGTCNAARAARAARCCNYTNATHGCNGAYGTNGTNAAYCARTTY YTNCCNGTNCARGGNATHTGYGAYAAYGAYTAYAARCARYTNGARATHATGTGYMGNMGN GTNYTNGAYCCNTAYTTYTCNGARCARYTNGARGARGCNCCNAGYTTYGGNGTNYTNTTY ATHGAYAARATGTGYGARCCNGGNGCNGARGTNYTNYTNGARGTNGTNMGNAGYGCNATH TGGAGYATHAAYCCNACNGCNTGGCARGCNTCNCCNTGGACNGARCCNGAYGTNGTNATH CAYGTNGARATHATHGGNAGYAARATHGTNYTNTGYGCNATGCCNCAYTAYATGAARTTY MGNCARTAYAGYCCNYTNGCNGTNCAYGARYTNGGNTAYGGNCARCCNGARGAYGARGAY YTNGTNAARGTNYTNACNAARTCNGARGARGAYGARGARAAYMGNMGN------------ ------------------------------------------------------------ ------------------------------------------------------AARAAR AARGCNGCNAARAAYAARGAYAARGCNGAR---GARAARCCNGARGARGARAARAAYGAR ACNGAYCARCCNGCN------GARGGNGCNACNGARGGNGARACNGTNGARGCNAGYGAR GARACNGCNACNGARCCNGAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGYATHGAYGTNYTNGCN GTNGCNGAYCARTAYYTNYTNCAYGAYYTNGTNCARTTYATHAGYTCNGTNYTNTCNCAY MGNTGYYTNTTYACNCAYACNAGYCARGAYATHYTNTGYYTNGCNTAYACNTAYAARYTN CCNGAYYTNGCNTCNGAYTGY---------ACNTAYAARGCNCAYGARGGNAGYMGNTTY ATGCARAARYTNATHAAYAARAARGGNGCNAARAAYAARAARCARTGGTAYAARCCNCAY YTNGGNGARCCNYTNGARGTNGGNCARAARAARYTNAARAARGGNATHTCNCCNGCNCAY AGYATHMGNYTNMGNCARYTNAGYCAYGTNYTNTAYGAYAARATHGCNGARATHATHAAY ACNGGNGARYTNTCNCARGARATHYTNGAYACNCARGTNGCNATHACNTCNGCNGTNATG AGYAARGAYYTNCAYAGYYTNAAYGTNTAYTGGGAYGCNGAYMGNCCNGAYTGGGARYTN GTNGARCARACNYTNCAYGCNCAYGGNGGNAARYTNMGNAGYYTNYTNATHTCNTAYCAY ATHYTNGGNMGNATHCCNCAYATHGTNTTYGTNAARAAYAARGCN---GGNGCNAAYYTN AGYCAYYTNAAYCARYTNTTYGAYATHGCNGAYTAYGGNCCNGAYTAYATHTGYMGNGGN YTNATGAARACNAGYACNGTNACNYTNACNYTNACNGAYACNATGGAYCAYATHAAYYTN GARACNTCNTTYGTNTCNAARGGNYTNGARGAYGTNATHATHAAYTCNGCNGTNAARCAR CARGARAGYATHGAYTCNMGNYTNGARGTNAAYGARTCNAGY---MGNAAYGAYATGTAY GTNGTNGAYTCNACNCAYGARATHYTNGGNGAYAAYGARGTNGGN---ACNTCNAAYYTN TAYGGNYTNAAYMGNGAYGARATGATGAARAARGTNGTNGCNAARAARTCNAARGTNAGY TTYAAYATHGAY------------------CCNATGCCNCCNGGNTGGGARGCNMGNTGG GTNMGNGARCARAAYMGNTAYTTYTAYATHAAYCAYCARACNAARTCNACNCARTGGGAY GAYCCNMGNYTNACNGCNCARCCNCARGCNCAYGCNGCNGCNGCNTCNYTNACNCCNCAR MGNGAYCCNMGNCARGCNCAYCAYCARCARGCNTAYCCNATGCARGAYAAYCARAAYCCN TCNCARGCNYTNYTNGCNAARYTNCAYAARGAYTTYCCNAAYGCNACNAARGCNYTNYTN TCNGAYATGYTNGTNGGNTGYTTYAAYAAYGARMGNGARACNMGNGARCARYTNGCNGAY YTNGGNTTY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGNTTYCCN GARGGNGCNGGNYTNAGYTCNCAYACNGCNTCNATGYTNAAYAAYAGYGAYATHYTNGTN ATHGGNMGNGARGGNAGYYTNMGNATHCARMGNAARTAYGGNAAYGCNTAYATHYTNCAY GGNAGYGTNYTNTCNGGNAAYTTYACNTAYMGNGARTAYAGYGAYAAYGTNACNTCNMGN TCNGGNCAYACNTCNAAYGTNATHAGYAAYTCNGTNTTYATHGTNGGNGGNMGNAAYGAY AARYTNYTNGARAARGCNTCNGGNTTYMGNCCNGCNACNCARCARACNTGYTCNATHYTN TCNTCNGTNGTNAAYAAYATHATGYTNAAYAAYCCNMGNCCNATGACNAARYTNCCNTGY GGNMGNAARAAYCAYATHTCNGCNTCNGAYCARCAYTGYATHYTNYTNCAYGGNGGNGAR ACNTTYGAYGGNMGNAGYMGNGARCCNGTNGGNGARATGTAYATHATHACNYTNGCNTCN CCNACNAAYTTYTAYAARYTNAAYACNACNAAYYTNCARMGNGCNGGNCAYGTNTGYTGY GTNTCNCARGARGAYGTNTTYATHCAYGGNGGNTTYAGYGGNMGNTCNATGGTNAAYTCN GAYYTNTAYMGNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AARAGYGTNAAR ATHAAYGCNTCNATHTAYACNAARTCNAARTTYATGGGNATGTCNATHGGNGTNGCNATG GTNGGNAARYTNCAYYTNMGNYTNGARGARTTYGAYGARGARTAYGTNTTYAGYYTNCCN AGYGCNTAYGCNMGNTCNATHYTNACNGTNCCNTGGGTNGARYTNGGNGAYAARGTNTCN YTNACNTGYGAYAARACNGGNTAYAAYGCNAGYATHGTNTTYAAYACNAARCCNTTYTAY GGNGGNAARYTNCAYCAYATHACNGCNGARGCNAARAAYACNMGNACNGGNGARAGYGTN TGYAARGTNCARGGNCARTGGAAYGGNATHATGGARTTYAGYTAYGCNAAYGGNGAYTCN CAYTCNGTNGAYGTNTCNGARYTNCARGTNACNMGNAARTCNGTNMGNCCNATGGAYAAR CARGAYGARCAYGARTCNMGNMGNYTNTGGCAYCAYGTNTCNAAYGCNYTNAARYTNAAY GAYGTNAAYACNGCNACNGARCAYAARMGNCARYTNGARGARGTNCARMGNGARMGNGAR MGNCAYMGNAARGCNATGAAYAGYCCNTAYATHGGNAARTTYTTYGAYAGYGTNGAYGAY ACNTGGATHCAYAARAARTTYCCN---------------------------AARAARGTN YTNCCNAARAAYGARAARGARTGGGAYTGGTGGGTNAARYTNMGNGAYCCNAARGARATH YTNAARCARCAYGARTCNTTYYTNTAYTGYGARGTNGTNTTYTAYATHYTNAGYTTYTTY ACNTTYGTNCAYGCNTTYAARAAYGGNGGNMGNTAYAARTGGYTNTGGYTNGCNACNYTN GCNCAYGGNYTNACNGTNGARTGYGTNTCNTAYTAYGTNCCNGAYATHGAYAAYTTYTGG CAYGCNCARAGYATGGTNATGTTYYTNGGNCARMGNYTNCCNYTNCAYATHATHYTNYTN TAYCCNGTNTTYATHTAYACNGCNGTNGTNGCNGTNTCNCAYATGAAYYTNMGNTGGTGG GCNGARCCNTTYGCNGTNGGNYTNTCNGTNGTNYTNATHGAYGTNCCNTTYGAYATHATG GGNGTNAARYTNYTNTGGTGGTCNTGGCAYGAYGAYGAYCCNAAYGTNTAYGAYMGNCAY TAYTAYGTNCCNTGGACNTCNTAYTAYTTYCAYGCNGCNTTYGCNTCNTCNTTYGCNTTY ATHTTYTTYAAYYTNAARAARYTNGTNTGYTCNAARGCNYTNAARTTYCARAGYAGYGGN TTYTTYYTNGARYTNCCNGTNGTNATHYTNACNGGNYTNTTYTCNATGCCNYTNGGNGTN YTNCARTTYGTNCCNATHTAYCAYCCNYTNCAYGAYACNYTNGGNATHCAYTCNGARGTN TGYGTNYTNYTNTAYYTNGCNATGTTYGTNTTYATHGTNTGGAGYGCNGAYMGNMGNCCN YTNGARYTNGCNMGNCAYAARAGYGGNGGNATGTTYAGYYTNYTNTTYYTNAAYGTNYTN ATHCAYTAYGCNYTNTAYATHTAYYTNGTNTTYACNGCNAAYCCNACNAARATHMGNTCN TCNGGNYTNCAYCARCCNATHGGNCCNTGYAAYAARAGYGTNAARGTNCARACNCCNATG GGNCAYGTNYTNAARAARACNCARTAYYTNTGYYTNAARAAYTAYTCNGARGAYTAYTTY ACNYTNGAYTGYYTNAARAARCCNCCNGCNGAYAARACNGARTGGTAYACNATHTGYGGN ACNGCNTAYCCNAAYCAYAARGARTAYATGGTNATHGTNTCNGCNTTYTGYGCNATHGGN YTNTTYTGGTTYATHCARATGTTYTAYMGNTCNGGNATHCARCCNMGNATHGARTCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY GAYGARGAY---------YTNCCNCCNGGNGTNMGNAARCARAAYMGNTGYCAYAGYAGY AGYTCNGARTCNGARAAYGARGCNGAYAAYAARATGGARTCNMGNGAYTCNTCNGAYTCN GAYTCNGAYAARTCNGAYCAYAGYTGYTCNAAYAARGAYAARGTNGTNGARCARACNAAY ACNGTNACNGCNTCNGARGARAARAAYGAYAAYGTNGCNACNAAYACNAARAAYAARCAY AGYMGNTCNMGNTCNCAYTCNAARTCNMGNTCNMGNTCNGCNTCNCCNMGN------AAR MGNAGYMGNCARTCNMGNTCNMGNTCNMGNGAYMGNMGNCAYAARMGNGAYMGNAARCAY MGNTCNAAYMGNTCNAARTCNAARGARMGNMGNMGNTCNMGNGAYMGNCAYMGNCAYAAR AARGAYMGNAARMGNAGYMGNAGYMGNAGYMGNAGYMGNGAYMGNMGNGAYMGNAGYAAR GAYMGNMGNMGNMGNAGYMGNAGYMGNAGYMGNMGNAGYMGNAGYMGNGAY--------- ------------------GAYMGNAGYMGNAGYMGNMGNCARAGYACNMGNAGYCCNAGY CCNMGNAAR------GTNATHAARTTYGGNGAYAARGTNATHAARCCNGGNGCNAGYTTY GGNMGNCCNATHTCNAAYTCN------TCNAARCCNATHACNTTYAARGARAARATGMGN CARGARYTNATHAARGCNATHGARGAYGGNGCNGAYACNGCNGARGTNYTNGCNAAYAAR GGNGGNTCNAARATHTGYACNCARTCNGCNGGN---GTNCARCAR------GCNCCNACN AARGCNAARCCNCCNYTNCCNYTNATGGAYAARATHATHTCNTGYCCNGGNGGNATGCCN CCNAAYACNGTNACNGCNTCNGARGCNGTNATGCARTCNATGYTNGCNYTNCARAARGAR ACNACNGARAARACNGGNATHGARATHCCNAARTAYTAYAAYCCNGCNGCNATHAAYCCN ATGAARTAYGCNGARCARGTNCARAARMGNAARYTNYTNTGGTCNAARGCNAARGAYAAR GAYGTNAAYTCNCARTGGCAYGCNACNGGNYTNACNGGNGAYGCNGAYGAYAARTCNAAR GARAARTTYMGNAARYTNATGGGNATHAARGCNGAYGGNGGNAAYGGNTCNGGN------ ------------GARGGNGARCARGARGARAARCAYAARCARYTNTTYGAYCARYTNAAY AARGARTAYGARTTYGCNMGNATGACNACNCAYACNCAYMGNGGNGTNGGNYTNGGNTTY GGNTCNYTNGGNTTYCARCCNCARCCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GTNATH MGNGTNGARGGNGGNTCNTCNGTNCCNACNATHYTNTCNTCNAARTGYTCNTTYCAYCCN GARTTYYTNGARAARTTYCCNGAYGGNCARGTNCCNTCNTAYATGCARGTNCCNGAYATH CCNACNAAYAARAARGAYATHYTNTGGAAYAARAARMGN------AGYGARCARGARAAY GTNGAYTCNGTNCARGARTCNAARATHATHACNGCNATGGCNAGYTTYMGNYTNCCNTCN CARAAYGTNCCNGAYTGGGCNAARCAYATGTCNGAYAAYCARTGG--------------- ------------------------------------------------------------ ------------------------------------GGNTCNCCNTTYYTNTTYGAYGAY CCNTCNGCNAGYGARACNGGNCCNYTNMGNGTNGCNAGYTTYAAYATHMGNCAYTTYGGN AARACNYTNATGAGYCAYGAYGAYATHGTNTCNAAYATHGTNAARATHTTYCARMGNTAY GAYGTNGTNYTNGTNATGGARGTNMGNGAYTCNACNCAYAAYGCNYTNAAYATHYTNAAR TCNMGNYTNAAYTCNACN---AGYTCNTGGGAYTAYATHAGYAGYGCNCCNATHGGNMGN ACNAGY---TAYAARGARCARTAYGTNTTYTTYTAYMGNCCNAAYTCNGTNAARGTNATH TCNTCNTAYCARGTNTCNGAYAGYGCNACNGAYGTNTAYGARMGNGARCCNTAYGCNGTN GARTTYGARTAYATHTCNATGCAYAGYGAYGCNAARACNMGNATHGTNTTYATGGGNATH CAYACNAARCCNACNYTNGCNYTNAGYGARYTNCARGCNYTNCCNAAYGAYGTNAARAAR GTNGCNTCNCAYTAYTCNGAYTCNATGGGNGTNATHACNATGGGNGAYTAYAAYGCNGAY TGYTCNTAYGTNAAYCARAARGARCARAAYGCNYTNGARATHTTYCAYGGNCARGGN--- TTYMGNAGYCARATHCCNGAYGAYGCNGAYACNACNGTNTCNMGNAAYACNGAYTGYGCN TAYGAYMGNATHGTNGTNTAYGGNGAYAARATHGAYATHMGNAAYAGYAAYGTNTTYAAY TTYGARTCNYTNYTNCAYATGACNAARGARGARGCNAAYMGNATHAGYGAYCAYTAYCCN GTNGARTTYYTNYTNTAYMGNTTYAGYATHAAYYTNTGYAAYGGNCCNACNTAYGAYTCN GGNTGYGCNYTNCAYTTYAAYCCNMGNTTYGAYCARAAYCARGTNGTNMGNACNCAYYTN CARGAYGGNAAYTGGGGNCCNGARGARAARGCNGGNGGNTTYCCNTTYAARMGNGGNCAY GTNTTYGARATHCAYYTNAARGCNACNCAYCAYGGNTAYAAYATHYTNGTNAAYAAYMGN CAYTTYTGYGAYTTYAAYCAYMGNATHGCNAARGARAGYATHCARTAYATHTAYATHGAR GGNGARGTNGTNATHCAYTTYATHCARTTYMGNGGNGGNGGNTAYGCNCCNGCNCCNAGY TAYCCNCCNGCNCCN---------------GTNCCNGGNTAYCCNCCNGCNCCNGTN--- ---------CCNGGNTAYCCNCCNGCNCCNGGNTAYCCNCCNGCNCCNGCNTAYCCNTCN ATGGGNGGNGCNCCNATHTAYAAYCCNCCNGTNCCNTTYACNACNCCNATHCARGGNGGN ATHGTNCCNGGNAARATHGTNTAYATHTCNGGNATHCCNAAYTCNAAYCCNAGYMGNTTY ACNGTNAAYYTNCARTGYGGNCCNTAYGARTCNGGNGAYTTYGCNATGCAYTTYGAYGTN MGNTTYAAYTAYGGNGAYAGYTAYAAYAARATHGTNMGNACNCAYAARCARGGNGGNAAY TAYGGNAAYGARGARACNACNYTNGGNCAYTTYCCNTTYTTYCCNAAYACNCCNTTYGAR ATGATGATHYTNATHGARCCNACNTCNTTYAARATHGCNGTNAAYAAYCARCAYYTNYTN GARTTYTTYCAYMGNATHCAYCCNTTYAAYMGNGCNGAYCAYGTNAGYATHGTNGGNGAY GTNMGNYTNACNCARGTNMGNTTYCAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AGYAAYMGNATHACNGARGTNGTNGARAAYGTN CCNGARYTNGARAARAARMGNAARATHGGNGARCARMGNYTNCAYGAYTGGYTNCARAAR GTNGGNAARCCNAARMGNGTNATHAARAGYCARGTNCARGTNACNMGNTCNAAYGAYYTN AARGTNAAYGAYTTYATHMGNCARYTNCARGARAAYTTYTCNATHYTNTCNGARATHGCN AGYCARGTNAAYAARATGGARGTNATGATGCCNGARGCNGAYMGNTCNAAYTGGCARCAR GGNTGYAAYATHGTNGARCARYTNAARGCNAARCAYGCNGAYATHCARGAYGTNATHGAY GARMGNAARATHAARGAYGCNCARTGYAARTTYAAYMGNATHAARGTNAARAARMGNMGN YTNAARMGNTCNGCNCARACNAARTTYCARGTNMGNCARGARATGACNAGYGTNMGNATH GTNAARGARMGNGARATHGAYGAYTGGCARAAYAAYYTNMGNAAYGAYATGAARGARGAR AGYYTNAARMGNAARMGNAARCARGARATGGAYMGNTCNYTNAGYGARATHACNAARAAR ATHAAYGAYGCNAAYMGNYTNATHGARACNATGACNGCNYTNGARAARYTNMGNYTNATH MGNCARGAYGCNGCNAARAARMGNGGNGAYGCNGAYYTNGGNGARTCNMGNGAYAGYTTY GARCARAARATHTCNGAYATGACNMGNYTNGTNMGNTGYCARYTNGARGTNTAYAARGAR GARGARGARAGYATHMGNAAYGTNATHCARTCNGARCARGAYGCNACNAGYGARAARGAR MGNAARYTNCARCARCARCAYGARGTNGARGTNGARCARCARAARAAYGTNGAYYTNTAY AARAARYTNTTYGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AARCAYGAYTGGAARAAYGGN YTNMGNGARYTNGTNCCNAARTCNCAYMGNMGNTGGGCNAARGCNTTYATHCARAAYTGG MGNAARGARAAYYTNAARAAYTCNACNAGY------------------------------ ------------------------------YTNCAYAARTGYMGNAARAAYTAYCCNGAY YTNAARATGGCNGTNTGYCCNTAYAAYGCNAAYCAYGARGTNAARGCNCCNGARYTNAAR TAYCAYATGACNCAYTGYCCNAAYMGNACNYTNATHGARMGNGAYATGGAYCAYAAYGCN ATHAARAAYGCNAAYGAYGAYTAYAARATH------ATHAARGGNAAYACNGAYYTNCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNGAYGAYTCNAAYCAYTAYGTNGAYCCNCCNAARAARGARGARGGNTTYGARATHYTN GARYTNACNGTNCARYTNACNGTNCAYTCNCAYTCNAARTTYAAYGTNCCNGCNYTNTTY ATHCARTGGGARGCNGTNATHTCNMGNTCNGGNACNYTNCAYTCNTCNYTNCCNGARGTN TGYCARAAYTGGATHACNCARAAYCCNCAYGGNAARATHGTNYTNGTNAAYGAYGGNAAR AAYAGYCCNAARAAYGGNTTYGTNGAY---------AGYAARAARATHTAYCARCARTTY AARTCNYTNTCNAAYAARATHCAYTAYCCNATHTTYATHYTNAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGGAR AAYAAYAAYGCNATHGCNGCNAARCCNGARYTNGAYGGNGARTCNAARATHGARGAYGTN AARCCNACNGTNGARGAYACNGAYTCNTCNCCNAAYAAYMGNMGNTAYAAYAAYMGNMGN MGNMGNCCNATHMGNMGNGAYGTNAAYCCNGARGAYGARACNCCNAARGCNGCNATHMGN MGNAARGTNTGGGAYCAYTTYGARGAYGARAAYYTNGTNAAYGCNCCNMGNCCNTGYCAY TTYMGNATHCCNAAYTTYGARGGNGCNACNGARGCNGCNGAYAARYTNACNAGYYTNGAY GARTTYAAYGAYGCNAARACNGTNAARGTNAAYTCNGAYAARGCNCARGARCARATHMGN TTYYTNGTNYTNGARGCNGGNAARGARYTNGTNYTNYTNAAYCARAAYGARAARGAYYTN ATGGTNCCNACNCCNGARYTNAARTGYGGNYTNYTNAAYMGNGTNGARGCNCCNGARGGN GCNAAYAARGARGARYTNAARCAYTGYTGYACNACNCARGGNGTNAARGARAAYAGYAAR GARATHGGNYTNGARGAYAARGTNAARYTNGAYATHATHGTNGTNGGNAGYGTNGCNGTN TCNMGNAAYGGNGAYMGNATHGGNAARGGNAARGGNTAYGCNGAYYTNGARTAYGCNATG ATGMGNACNATGGGNGCNGCNAAYGCNAAYACNGTNGTNGTNACNTCNGTNCAYGAYTCN CARGTNGTNGAYATHGAYGARGARYTNGTNGGNGARCAYGAYATHGCNGTNGAYTAYATH YTNACNCCNACNGARGTNATHAARACNAAYTGYAARMGNCARMGNCCNTCNGGNGTNATH TGGAAYCAYYTNGARGTNAAYAARTTYTAYCARATHCCNGTNYTNMGNCARYTNMGNAAR AAYGARAARGAYGAYGGNAARGAYGTNYTNYTNAARGAYCARAARGARGARGAYGARGAY CCNGTNGAYACNATGGARCCNCCNMGNCCNMGNMGNTTYGTNMGNAAYTAYMGNAAYGCN GGNGGNTTYMGNGGNMGNGGNMGNTCNTAYGGNGGN---TAYMGNMGNGGNGGNAGYMGN MGNMGNCARTAYGAY---GGNGARGAYAGYAAYAARGARAAYMGNGAYGGNGGNGARGAY TCNGGNGCNGAYGGNGAYAAYGARGGNMGNTCNAAYMGNMGNAAY--------------- AAYTAYMGNAAYMGNMGNTTYMGNMGNGGNGGN---------MGNCCNMGNGCNTCNGAR TCNGARCAYAGYGAYGGNGGNGCNGAYGARAAYMGNGARGAYGGNGAYGARAARCCNMGN CARMGNGGNTTYAAY---AAYCCNMGNMGNTTY------------AAYCARMGNMGNMGN TAYGAYAAYMGNMGNGAYAAYMGNMGNGAY------------GAYCARTCNGGNAGYGAY GGNGARCARAARAAYTCNGCNGAYGARGAYGGNGARAAYMGNMGNCCNMGNMGNAAYMGN ATHCARACNAAYCCNGAYGCNGTNGTNTGGGTNGGNTCNYTNTCNMGNACNYTNMGNGTN AGYCARYTNAARGTNGARYTNMGNAARCAYGARGTNAAYCCNATHMGNYTNYTNTGGMGN GGNGGNCAYGGNTTYGCNTTYYTNTTYTTYATGGARGTNGARGGNGCNAARGARGCNGTN AARGTNYTNTCNGGNMGNGARYTNTGYGGNMGNGARATGAARGTNGARATGGCNAAYAAY GAY---------MGNMGNMGNTCNAAYTCNAAYMGNAAYGARAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GTNGARAARGARAARTAYATGATGGARTGGAAY---GTNCARGAYTAY TTYCARTCNYTNCCNTCNCCNMGNGTNYTNAAYAAYCAYYTNCCNTTYAAYMGNCARCCN AARGAYYTNYTNGTNACNAARCCNAARGTNGTNTAYYTNTAYMGNAAYYTNAARGAYGTN GCNGTNTCNTAYTTYCAYCAYCAYAARGGNATHGCNGARTCNTGYTAYAARGGNGAYGAY TTYAAYTCNTAYGTNCARMGNYTNGTN--------------------------------- ------------------------------------------------------------ ------------------GAYGGNYTNGTNGARTAYGGNAAYCCNTTYAARTTYYTNMGN GARTGGGAYGARGCNATGMGNAAYCAYCCNGAYYTNCCNGTNTAYTGYTGYMGNTTYGAR GAYATGAARCARGAYCCNGTNTCNCARATGMGNAARATHAGYGARTTYYTNGGNAARAAY TAYGAYGAYGCNTTYYTNCARAGYGCNTGYACNAARACNAAYTTYAARAAYATGAARGAR ACN---------------ATGGGNAARGCNATGCCNGTNTTYTAYMGNAARGGNGTNGTN GGNGAYTGGAARAAYCAYTTYACNGTNGCNYTNAAYGARTGGTAYGAYGAYGTNATHGAR AARGARATGCCNGGNATHGGNYTNAARTTYMGNTAYACNYTNYTNATHGGNTAYGGNATH GGNMGNTTYTCNTCNTGYCCNATHGCNMGNTAYCARYTNGCNTTYYTNYTNYTNYTNCAR GARAARYTNCARACNGARCCNCCNYTNYTNTAYGAYCCNGTNTTYTCNGCNGARGARATH AARTTYYTNGARGARYTNGGNTGYGARYTNATHCCNTTYAAYGARGARGGNAARCAYGTN TGYCCNGTNCCNACNATHGTNTTYATGCCNCAYTGYGGNAARGCNYTNTAYAAYAAYGTN YTNTGGGCNAAYATGACNMGNYTNCCNAAYYTNTTYATHATHGGNAAYAGYTTYTCNMGN ATGATGGARAGYACNCCNGGNAARCAYYTNATGAARACNGCNAAYTAYGTNATGAARGTN TCNCCNTAYATGACNGARACNATHAAR---TCNTCNACNTTYACNCAYTGYGAYGTNTTY AAYGAYYTNTCNYTNCAYGTNTTYCAYCCNTCNACNYTNAARAAYGCNAGYCARMGNTTY TGGGARGARAAYGCNGARCCNGARTAYGAYGARGARGAYGTNGARATHATHCARAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AGYYTNTGGAAYGAYATHCAYAARTTYGTNGAYAARGGN CARTTYATHCCNGTNGGNGGNACNTGG--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TCNACNCARTCNGARGCNGARYTNGCNYTNAGYGTNAARACNGGNTTYAGYTAYCARGAR YTNAARGARTCNACNYTNAAYTTYAGYGAYGAYAAYATHYTNGGNGARGGNGGNTTYGGN GTNGTNTAYTAYGGNCARYTNMGNGGNYTNGAYTGYGCNGTNAARMGNTTYAANNNNAAR GAYGAYAARGCNACNGAYTCNAAYGARCARATHAAYAGYGARYTNACNGCNYTNYTNAAR TTYCARCAYGARAAYATHGTNACNYTNTAYGGNTAYGCNGTNGAYGGNCCNGAYYTNTGY YTNGTNTAYCARTAYYTNTCNAAYGGNTCNYTNGARGAYMGNYTNATGMGNAARAAYAAY TCNGCNCCNYTNTCNTGGGARMGNMGNYTNAAYATHYTNGTNGGNTCNTGYCARGCNATH AGYTTYYTNCAYAARTGGGGNGAYACNCCNYTNATHCAYGGNGAYGTNAARAGYGCNAAY ATHYTNYTNGAYCARCAYYTNGARGCNAARYTNGCNGAYYTNGGNCARTCNMGNTAYGCN AAYAGYMGNACNTCNATGACNGGNAGYTTYACNCAYATHACNYTNGCNGARACNAAYACN MGNCARTAYGGNACNMGNCCNTAYYTNGCNCCNGARGTNAARACNGGNTCNMGNYTNTCN ------ATHCARTCNGAYATHTTYGCNATGGGNGTNGTNATGYTNGARGTNGCNAGYGGN TTYCCNGCNTAYGAYAAYAARMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GGNACNAAYYTNYTNGGNGTNGAYCCNATHGCNAAR AARYTNYTNAAR------GAYAAYYTNAAYGGNGCNTCNYTNGARGAYMGNATGGTNGCN GARCARTGGYTNGARTTY------------AGYCAYGAYGTNYTNAAYATHGARAARAGY GGNGAYAARGARMGNATGAAYGTNATHYTNAARGAYYTNAAYTGYTAYATHAARGARMGN GTNTAYTTYGTNMGNCARGARTGYACNGCNGTNGAYGTNTTYYTNTAYCAYAGYYTNTTY CCNGTNTTYGARAARYTNACNTTYCARGARAARGARAARGTNATHCAYYTNTCNMGNTGG TTYTCNCAYATHCARGCNGAYGARAARGCNMGNCARTCNYTNCARCCNYTNATGTTYYTN MGNACNATGYTNTAYACNGGNGTNTCNACNCAYATGACNTCNATHGAYACNATHYTNGCN TGYYTNCARMGNATHGCNCCNYTNTCNYTNGCNGARAARTGGGAYAAYGTNGGNYTNYTN GTNGARCCNTCNGGNCCNAARTTYATHAGYAARATHATGYTNACNAAYGAYYTNACNACN CCNGTNATGGARGARGCNAARGAYAARACNGTNGAYYTNATHGTNGCNTAYCAYCCNYTN ATHTTYACNCCNATGAARMGNYTNTGYCARGAYAGYTGGAARAAYMGNATHGTNATHGAY TGYYTNGARAAYMGNATHGGNGTNTAYTCNCCNCAYACNTCNYTNGAYGCNGCNCARGAY GGNATHAAYGAYTGGYTNYTNTCNGCNTTYGAYGTNGAYAARGARTCNATHYTNCCNGTN GARGCNACNGARTCNTTYGTNGAYTGYMGNTCNCAYGTNYTNGARGTNGAYYTNGAYCCN GGNAAYATGAGYGAYGTNTGGAARACNATH---ACNTCNAAYGTNTCNAARGAYTCNMGN YTNMGNMGNGAYAARAGYTGYTTYTCNACNCAYGTNATHMGNACNGGNTCNYTNGARAAR TGGMGNYTNMGNYTNGARTGYAGYAARTCNGARYTNAAYGAYGTNATGAARGGNGTNGTN AGYTGYCAYACNYTNGAYAARTAYTCNGTNTCNAGYYTNTCNAARGCNGTNGTNAGYAAR TGYGGNATGGGNMGNCARGCNGTNYTNAARGCNTCNYTNACNYTNGARGARGCNGTNCAR CAYGTNAARMGNCAYYTNAARYTNGARTAYGTNTGYYTNGCNAARGCNAAYGGNGCNGAY GAYATGMGNATHAAYACNGTNGCNGTNTGYGCNGGNTCNGGNTCNAGYGTNYTNAARAAY GCNAARGCNGAYYTNYTNYTNACNGGNGARATGTCNCAYCAYCARGTNYTNGAYGCNGTN CAYGCNGGNAGYAAYGTNATHYTNTGYTTYCAYAGYAAYACNGARMGNGGNTTYYTNACN CAYYTNCARCARMGNYTNAARGAYGGNATHGGNTCNTCNGTNGARGTNYTNGTNTCNGAR AARGAYMGNGAYCCNYTNGARGTNGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNAARGTNGTNCCNYTNCARTCNGGNGAYTGYYTNGGNTGYAARYTNGTNGGN ACNTCNGTNTTYATHACNAGYGGNGTNATHGTNATGACNTCNGCNATHGCNGGNAARAAR MGN--------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------CAYCARACNAAYMGN MGNYTNTCNATHCAYACNGCNGGNTCNACNYTNCCNCAYGARCCNAAYCCNAARTAYYTN GGNGTNACNYTNGAYMGNTCNYTNACNTAYMGNAARCAYATHGARAAYACNGCNAAYAAR YTNCARAARMGNAAYGGNATHGTNMGNAARYTNGCNGGNACNACNTGGGGNGCNACNCCN ACNGTNYTNMGNACNTCNTCNYTNGCNYTNTGYTAYAGYGTNGCNGARTAYTGYGCNCCN GCNTGG------ACNMGNTCNTCNCAYACNAAYAARATHGAYACNAARYTNAAYGAYACN ATGMGNACNATHACNGGNACNYTNMGNTCNACNCCNACNGCNTGGYTNCCNGTNATGAGY TCNATHGCNCCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GAYATGTCNGAYTCNGAYGCNYTN AARTCNCAYMGNAGYTCNAARGGNCAYAARAGYGTNGAYYTNATGGAYACNATGYTNGAR ACNMGNAARAARAGYYTNGAYTAYTAYGTNTTYCCNGGNTTYTTYCAYGGNGARTTYATH GARYTNCCNGCNCARYTNGARGCNCCNCCNGTNYTNCAYMGNATHACNAAYGCNCARGAY TTYAAYCCNGGNTTYAARAARTTYTGGAARAARYTNTTYYTNTCNGARGCNTCNTCNGCN GTNYTNCARGAYTCNTTYTGGTGGATHTTYYTNGAYAARTTYAAYAARACNCARGGNGTN GARGARGAYAARGAYTGYYTNTTYGAYMGNATHTCNGAYAGYTAYGTNGCNYTNTTYACN AGYATHAAYACNGAYGTNAARGAYAARTTYYTNTCNGTNTAYCCNAGYTGYYTNTCNCAR GCNYTNTAYTAYACNTAYCARGARGCNTTYCCNGARTCNAARTGGMGNTTYGAYGARAGY TTYAARCARTAYYTNGTNAAYYTNGTNTAYGARTGGGTNACNGGNYTNMGNCCNGTNCCN GGNGTNTGGAARGCNTGGAAYGARGARGGNYTNGARGGNAGYCAYACNGGNMGNGARAAY GARACNGCNAARAARATGYTNGARGCNGCNGCNYTNAAYAARAARGTNGARATHAGYYTN GAYATGGAYTCNTTYGCNAARGTNATHGAYAARYTNGGNCAYGAYTCNGARGCNAAYYTN CARGGNCAYATGTCNMGNGARGTNACNAARACNTCNAAYMGN------ATH------TCN GCNCCNTCNMGNGGNMGNTTYAAY---CARGARTCNCAYCARATHGGNCCNGGNCCNGAY TAYGARMGNGTNAARTTYAAYACNTCNGGNMGNAGYCCNYTNATHTCNCAYTAYYTNCAY ATGMGNCARYTNMGNAGYTAYAARCARCCNGGNATGAARGTNMGNMGNACNGARATHYTN AARYTNCCNCCNGAYGGNCCNACNTAYCARCARTTYATHGCNGAYACNYTNAAYAARGCN GARTCNYTNGARAARGARTAYACNMGNATHTGYGAYCARACNTCNTCNGCNATHYTNGAR YTNGARAARTAYAARMGNGAYTCNAAYAARGARATHGGNGARATGAARAARGCNYTNAAY AAYATHAARACNATHCCNGARMGNMGNYTNYTNATGGAYAARATHTCNGARTAYAARGAY YTNGTNATHAARGARAARCCNGTNTTYGARACNTCNATHTCNCARACNGAYATHAAYTCN TCNACNTCNTAYTCNTCNGAYGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CCNCARATGATGCCNGAYTAYYTNTGGCCNYTNTCNCARTTYGGNCARTAYATG GCNGCNAAYCARTTYAAYTTYTGYATHGCNTGYTGYTAYATHGTNATHATHTCNCAYAGY YTNGARGCNGCNTAYGCNGGNAARGTNTGYAGYGAYMGNGGNTAYGCNGTNTCNACNAGY ATHAARTGGGTNGTNTCNATHTTYATHATGGGNTTYCCNTTYATGYTNMGNYTNYTNCCN CAYAARCCNGARYTNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYGTNACNAARGGNTAY ATGYTNCCNCCNGAYYTNCARGTNAARMGNGARAARGCNCARMGNGCNGTNGARYTNTCN TAYAARAAYTTYGCNGAYTCNACNYTNTCNTCNMGNTCNAAR---YTNGCNTCNCARCCN MGNCCNAGYTCNGCNCCNTCNCCNTCNMGNAARAARGARGTNAAYTTYGAYYTNMGNGAR GAYAARMGNATGTAYYTNCCNTGGATHCCNGCNGGNTGYGCNCCN------TGYAARCCN MGNCARMGNTCNTCNAGYGCNGAYMGNAGYCCNTTYTAYGTNMGNTCNYTNGARGAYCAR GAYTCNTGGYTNTCNATGTCNGARMGNCARGARCAYAGYACNGCNATGCAYGAYGGNTCN CCNAGYGARGCNGCNTAYGGNTAYMGNTCNYTNCCNACNGAYMGNCARYTNMGNTCNTGY GAYGTNTCNGARTCNTTYGTNGAYYTNATHGARAARMGNATHYTNTAYMGNATGYTNAAY AARAARGCNGGNTCNACN---------------GGNMGNATGTCNMGNAARGAYGAYGAR GCNYTNGAYATHACNGAYYTNACNGTNGAYAARTCNTAYGAYGCNTCNAGYYTNAAYACN ACN---------------------GCNGARGCNGCNGGNATGATGGAYGCNCCNACNYTN GARAAYATHMGNYTNAARYTNGAYGAYATGGARMGNAARMGNMGNGARATHMGNCARMGN TGGGGNACNYTNAARTTYGTNGAYACN------------CAYMGNMGNACNAARGTNGAR YTN---AAYGARTGYCCNGAYGARCCNACNGCNATHGAYTTYAAYACNATHACNCAYCAR GAYAARTAYCARTGGAAYACNGGNTCNATGAAYAARGAYTGGGCNGARGARCCNYTNYTN TTYACNAARTCNAGYAARAARTCNAARCAYCAYTTYAAYCAYCCNTCNATHCAYTCNAAR MGN---------------------------------ATHCARYTNGTNGAYATHAAYCAR GCNTGYYTNGAYMGNATHYTNGARGAYMGNGAYMGNYTNGCNTAYCAYCAYCARAARCAR TCNCAYCAYCCNACNGGNAARTTYAAYCCNTGGACNYTNATGGARCARATHTCNGARGAR ATHYTNAAYGAYTGYYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CARCAYGARATHATGTCNATGYTNATHCARCARGGNGCNGAYGTNCAYGCNGCNAAYAAR TTYGGNAGYACNGCNYTNTGGAAYGCNGTNTAYCARTCNTCNCCNAARTGYGTNYTNYTN YTNYTNAGYCARAAYGCNTCNATGGAYGTNGTNAGYCARGGNACNTAYCCNTTYTCNAAY GARGARMGNGTNYTNCAYCARGARGGNATHGTNAAR---ATHTAYCCNGAYAARCCNAAR TCNYTNYTNTGGGTNGCNGTNGAYMGNATHGGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CARATGACNGTNTAYTCNGCNAAY ACNYTNTCNAARTCNAAYTTYTTYATHCCNAGYGCNACNACNTAYGCNAAYCAYGCNGTN TGYACNYTNGGNCARTCNYTNCAYACNACNGGNTAYTAYCCNCAYACNYTNYTNYTNTGG ATHTCNMGNAGYYTNCCNAAYTCNATHTGGATGTGGGCNGCNGAYAARTTYAAYAGYTCN YTNMGNMGNCARGCNAARYTNMGNATGGCNYTNACNACNTCNTTYYTNGTNGCNYTNGTN GCNGCNGTNGGNYTNGTN------------------------------------------ ---------------------------------------CARTGYCARMGNACNMGNCCN GCNGARGGNTGYACNGGNAARGTNATGGAYATHTTYTTYGTNYTNGAYTCNTCNTCNTCN ATHTAYATHAAYGAYTAYATGTCNCARCAYMGNATHACNMGNGAYATHATHGGNAARTTY GAYGTNAGYGCNAGYAAYACNMGNGTNGGNYTNYTNACNTTYAGYGAYGAYYTNGARMGN CCNGTNATHGGNYTNAAYMGNTAYAAYAAYATGAAYGARYTNYTNAAYGCNATHTCNGTN CARAAYYTNCCNTAYMGNACNGGNGTNACNAAYACNGAYYTNGCNATHMGNTAYGTNMGN CARYTNAAYGARTTYMGNACNGAYATHACNAARGTNATHGTNGTNATGACNGAYGGNGGN TCNMGNAAYCCNGGNAGYACNTCNMGNGARGCNGARYTNGCNMGNGCNGCNGGNTTYTAY YTNTAYGTNGTNGGNATHGGNCARTAYYTNGARGARMGNGARTGGMGNGCNATHGCNAGY GAYCCNGAYGAYAGYTTYGTNTTYAAYATHACNTCNCCNMGNYTNYTNGARGAYGTNCCN TTYTCNYTNCCNACNMGNGCNTGYGARYTNCCNCCNATHATHYTNGGNGGNTCNTGYGAR GTNAAYMGNGCNTCNGARYTNTAYTTYGTNGGNGGNMGNAGYACNACNAAYCARGCNGTN GAYGTNATHGAYTAYTTYACNMGNMGNACNMGNGAYMGNMGNGAYCARYTNMGNGCNACN TAYYTNATHGARGGNTGYAAYCARATHAAYAAYATHGTNYTNGTNAAYAAYGARCCNTTY ATHTGYGARMGNTTYAAYCCNGARACNAGYGARCCNATHGCNCCNATHAGYGTNGAYGAR YTNTTYCARCARGCNATHACNGAYATHMGNAAYTCNGGNCARGARACNAAYAARGTNATH ATGYTNTTYGCNGAYGAYGARATHYTNAGYTCNAGYMGNTTYCARYTNGCNAAYYTNGCN MGNAAYGCNGARAGYTTYGARGGNGCNACNGTNGTNYTNGTNGAYATHGGNATHMGNACN TAYMGNGAYTTYGCNYTNMGNATGGTNCARAGYMGNGARAAYATHATHTCNTTYAAYAGY GGNGCNATHTCNACNCARTCNGGNGCNCARGCNMGNGTNATHAAYACNGCNTGY------ ATGGCNGAYAGYTCNAAY---CAYCCNGAYYTNTTYGAYGCNCARCCNGARGGNYTNGGN TTYCCNAAYGAYGAYTTYGARAARGTNGAYGCNCCN---GCNGGNYTNGAYGAYGTNAAY GCNGCNGCNTCNGGNGCNTAY------------GAYCAYGAYCARGAYGCNGARATHTCN ACNACNACNGAYGCN------GAYGTNGCNGGNGARGARGARGARGAYMGNTTYACNACN GAYTTYCCNGAYGTNACN---------TCNCAYCAYCCNGARCCNYTNATHTCNTGGGGN GAY------------------GAYGGNGAYGGNGCNTCNGARTCNGAR---------ATH CARATHCARCCNTCNGCNCCNGTN------TCNGARAGYATHGAYCCNYTNGTNAGYTTY ---GAYGAYGAYTTYTCNGGNCARGAYAAY---YTNCARTCNTTYAAYTCNCCNATHCCN CCNACNAGYACNACNCCNGARCCNAARTTYCCNTCNTCNACNCCNAAYCCNATHCAYTCN CARYTNGTNGAYGARTTYYTNGTNAGYGARAGYAARGARAARGTNAARGARAGYAARCAR GTNTCNGAYGARACN------GCNGTNGARACNGCNAARGGNTCNTGGATHAARGGNGTN GAYCCNMGN---------------------------------GTNATHGAYYTNATHTAY TGGMGNGAYGTNAARACNACNGGNATGGTNTTYGGNGCNATGATGGTNGTNYTNYTNTCN TTYGCNATHTGYTCNYTNYTNAGYGTNATHGCNTAYYTNTCNYTNGCNATHYTNGTNGTN ACNTTYAGYTTYACNGTNTAYAARAARATHATGAGYGCNGTNCARAARACNAAYGARGGN CAYCCNTTYAARCARYTNATHGAYATGGAYATHGCNYTNAGYGARGAYAARYTNAARTGY GTNATHCARTCNGTNYTNAARAAYGCNAAYTGYACNGCNAGYGARYTNMGNMGNYTNTTY YTNATHGARGAYATGGTNGAYTCNATHAARTTYGGNYTNYTNYTNTGGGTNYTNACNTAY GTNGGNGCNTGGTTYAAYGGNATGACNYTNGTNATHYTNYTNGTNATHTCNATHTTYACN TTYCCNAARGTNTAYGARACNTAYAARGTNCARATHGAYAAYTAYATHGGNYTNGCNAAR GCNCARGTNGAYAAYGTNATHAGYATHATHCARAGYAARYTNCCNTTYYTNAARAARAAR GARAARGCNCAR------------TTYACNTGGYTNAAYMGNCAYGGNCCNGARTTYCAY ATHMGNGGNGAYCARGTNCARATHATHACNGARCCNCARCARTTYTAYGARATHYTNAAR ATHAARTCNMGNAARGCNMGNAARMGNGTNACNYTNGCNTCNYTNTAYATHGGNAAYGGN CARYTNGARCARGAYYTNGTNTCNTGYATHGAYGARGCNTGYYTNGCNACNTCNCARAGY ACNTCNTCNGAYYTNGARGTNAAYGTNYTNYTNGAYTTYACNMGNGGNTCNMGNGGNGAR CAYAAYTCNMGNACNATGYTNMGNCCNYTNATGAARMGNTGGCCNAAYGTNAARGTNGCN YTNTAYCAYACNCCNGAYYTNMGNGGNYTNYTNAARAARYTNACNCCNGARMGNTTYAAY GARACNATHGGNYTNACNCAYATGAARGTNTAYYTNTTYGAYGAYAGYTTYATHATHAGY GGNGCNAAYYTNAGYAAYGAYTAYTTYACNAAYMGNCARGAYMGNTAYATHYTNTTYAAY AAYTGYGARAGYATGTCNGAYTTYTTYCARCAYYTNGTNAARACNGTNATGTCNTTYTCN YTNCARYTNGARYTNGAYGAYACNYTNCAYYTNGCNCCNGAYTGGAAYATHCAYCCNTAY YTNGAYTCNGAYAAYGGNATHAAYTTYAARYTNGCNGCNMGNGARMGNATHAAYCARTGY YTNAARTCNGARGARTTYGTNACNGAYGAYTAYGARGAYAAYAAYAAYTAYGTNTTYAAR GARGARTAYGCN------------------------------GAYACNGTNGTNTAYCCN YTNGTNCARATGGGNCCNTTYGGNGTNCARAAYGAYGARAARGCNACNGTNGAYYTNTTY YTNMGNTCNGAYCARMGNGAYYTNATHYTNYTNACNTCNGGNTAYTTYAAYYTNACNGAY CARTAYTCNGAYGTNATHYTNTGYGAYGCNGARGCNAARTTYAARATHYTNATGGCNGCN CCNAARGCNAAYGGNTTYYTNGGNGCNAARGGNGTNGCNGGNGCNATHCCNTAYGCNTAY ATHTAYYTNGCNAAYAARTTYTAYAGYAAYGTNATGMGNYTNGGNCARTCNCARMGNATH CARATGYTNGARTAYGARMGNGARGGNTGGACNTTYCAYAGYAARGGNYTNTGGTAYTAY YTNCAYAAYGARTCNYTNCCNMGNYTNACNYTNATHGGNTCNCCNAAYTTYGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TCNTCNTCNGGNTCN---ATGTCNAGYGTNACNTCNTCNACN---GAYCARGAYYTN ACNGAYYTNYTNAAYCARYTNCARGAYGARTTYMGNCARYTNAGYAGYGAYCAYCARGAY YTNGTNCARCARYTNGAYMGNGCNATGGAYAARATGGARMGNYTNGAYATHGARCARGAR ATHGARGTNYTNACNTCNMGNATGGARTCNAARGCNCARCARATHGAYAARATGMGNAAY CAYCAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TCNCCNTCNACNCARCARCARCARCARCARYTNCARCCNCCNTCNAAYYTNCCNACNACN GGNATGCCNACNGTNGAYAGYAGYGGNTCNAGYACNGARTCNCCNACNCARAGY------ TCNGCNCCNTCNYTNCARAAYAARYTNGCNATGGCNTAYMGNGARACNACNTCNGGNMGN YTNTCNMGNGGNGGNGAYAARCCNACNTCNTCNACNAAY---------CARYTNTAYAAR CCNGCNGGNGGNYTNCARTCNTCNGARGTNGAYGAYGCNTCNGGNAGYACNGARTCN--- ---------------------YTNCARTCNGCNGGNGGNAAYMGNAARCARMGNGGNATH GGNMGNGTNMGNGGNMGNCAYGARGARACNGGNAGYGGNGCNGGNATHTCNTCNTCNTCN TCNTCNTCNGCNGCNAARTCNTCNTCNTCNTCNATGTCNATGCCNAARGCNYTNGCNACN TCNTCNGCNCCNAGYGTNTCNGARATGGCNMGNMGNGGNTCNCAYGGNAARGGNACNGGN ---------------------------GAYAARTCNGGNMGNYTNTCNGCNTAYGAYTTY CCNGAYGAYAGYCCNGAYGARGAYCCNGTNAAYTAYAARGCNYTNGCN------MGNACN GGNMGNAARTGYCCNGTNGAYAGYTCNGARAAYAAR---AGYTCNTGGACNGGNCCNGAY ACNCARGGNGCNGARGAYGGNACNGGNGAYAARAAYGARGCNCAR------------CAR TCNCARGAYTCNCCNGGNTTYTCNGARGCNAARYTNYTNAARCCNMGNTTYGGNAGYMGN GTNAGYCAY---GARGCNGAYTCNGGNACN---------CCNGCNGTNGAYAGYAGYTCN MGNGAYAAR---GCNCCNGARGCNGGNGAR---GTNGAYAGYTCNACNTCNTCNCCNMGN GGNTCNACNGGNGGNGGNCAY---------GGNCARGGNTCNTCNGAYTCNGGNCARTCN GCNGAYTCNCAYGCNCAR---GGNAGYCARGARTCNYTNCCNCCNGGNGAYGAYGTNGGN GGNTCNTCNAGYCARTCNGTNGCNAGYCCNTCN---------------------TAYTCN TCNGGNCARCCNGTNGTNTCNAGYATGATHMGNGAYCCNGARCARACNACNYTNTGYTCN MGNGAYCARGARCCNACNCCNYTNYTNTCNGCNCARTAYGARACNYTNTCNGAYGAYGAY ---ATHGARAGYCARCCNTCN---ACNACNCAYAAYTGYACNGTNTAYMGNTCNGTNGTN AARATHAARGCNTCNACNTCNGTNGTNGAYGAYACNYTNCCNYTNTGYCCNTTYAAYAAR TAYAARGARTGGGCNACNGAYGTNAARGAYGTNAARATGATHGARTCNYTNGGNGARGAY GCNATHATHTAYCARACNACNACNAAYAARATHGCNAARGTNATHTCNTCNMGNAGYTTY GTNACNGCNGGNAARAARGARTCNGAYGGNGAYAAYTTYTTYMGNTGYGGNGTNGGNATH GARTAYAAYAARCCNYTNGARGARGARGGNATGGTNMGNGGNATHTAYGGNCCNTGYGGN TAYMGNATHGTNCCNGAYCCNCARAAYCCNAAYCAYACNGTNTGYGARATGYTNATGCAR ATHGAYTTYGCNGGNAGYATHCCNAARMGNGTNATHAAYGGNTGYATGGCNAGYACNATH ACNTCNACNCAYGAYATGTAYATHGCNTAYATGAARAARAAYGGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARGARYTNGARGCNAARGCNGAYAAYGCNGCNYTNGARGTNGTNATHGARAAR YTNYTNGARTCNGGNCARAAYTGGGTNGCNGARGCNGCNAARGCNCARYTNGAYGTNGCN AARGCNACNAARAAYCAYAGYYTNYTNYTNAARAARGCNATGGAYGARACNTCNAAYATH YTNGAYAARGAYTCNGARTGGGARGCNGTNACNGTNGCNTTYAARGARMGNGAYAAYGCN GTNGCNMGNGCNAAYGARYTNGTNGAYGARGCNMGNAARAGYGTNGARAARYTNAARAAR GTNYTNGAYGARGCNAARTCNAAYAARGTNACNATGAARAAYCAYTCNATHTTYACNGCN ACNAARAARYTNTCNGAYTTYAGYAARGARATGTCNGCNGCNGGNTCNCARGTNMGNCAY GCNGAYGCNGAYGCNAARGTNATHYTNAARTAYAARGAYYTNGTNGAYAARGGNMGNAAR CARTTYCARGARGARYTNGAYAGYYTNYTNCCNGAYATHAARMGNGGNAARAAYAGYMGN AARYTNAGYGARGARGARYTNAAYGCNYTNATHGCNCAYGCNCAYMGNMGNATHGARCAR YTNCARAARCARATHGCNGARCAYYTNGCNATGGARCARAARMGNYTNACNGCNTCNYTN GARGARCARAARAARGARAAYAARAGYYTNACNGARTCNGCNATHGGNGAYGARMGNGCN CARYTNTTYGCNGARTTYGARATGGARMGNCARAARATGGARATHGARTTYTCNGCNTGG ATGGARGCNGAYGTNMGNAARCARYTNAGYMGNCARGCNGCNGCNCAYAGYGAYCAYYTN MGNGAYGTNYTNGCNGTNCARGARGAYCARYTNAAYAARGAYTTYGARMGNAARATGAAY ATHAARYTNYTNGARGARMGNGARAARTTYCARGCNGARACNACNGGNTGGATHTCNMGN YTNAARGGNATHGARGCNGCNGTNGAYGCNMGNGCNGCNAGYGARAARYTNGCNCAYACN GCNCARGAYYTNTGGYTNGCNTGYATHGCNYTNAAYTCNACNATHCARTTYGGNGARGAY GAY------GARGAYCCNATHCCNYTNCARCARCARGTNGAYACNGTNGTNAARTCNTCN GAYMGNCAYCCNTTYGTNGARACNGTNGTNAARACNATHCCNCARACNGCNYTNGARMGN GGNATHTAYACNGARAAYGARYTNMGNGAYMGNTTYGTNMGNGTNTCNCARGTNAGYMGN MGNYTNGGNYTNGTNGARGARTCNAGYGCNTCNYTNTAYAARTAYYTNGTNTCNTTYYTN CAYTCNTTYTTYACNGTNAAYAAYGTNGCNGCNTAYTCNGARAARGAYYTNGTNTCNYTN GARGARATGGAYAAYTTYAARYTNGTNGCNAAYGCNCARTAYTGGATGGAYAARGGNAAY YTNGAYATGGCNGTNMGNTTYATGTCNCARYTNGAYGGNCARTCNAARATHGCNGCNGGN GAYTGGATHGCNGARGCNAARYTNYTNYTNGARACNMGNCARGCNGCNAARACNATHYTN TCNTTYGCNTCNGCNACNGGNYTNGCNGCNACNTTYGARGAYYTNAAYGTNATHGARYTN YTNTGGAARCARGAYGTNGAYYTNGGNTGYGGNAARGARGTNTAYGAYTCNTCNTAYMGN GARGARYTNGARMGNAARMGNGARCARGARTAYATHAARCARCARGARCARMGNAARGCN GARGTNGCNGCNMGNGARAARGARGAYMGNAAYMGNCARYTNGARGCNAGYMGNTGGYTN AAYCARAAYTAYTCNMGNGAYGGNGARACNGGNGARTGGGTNMGNMGNCARAGYMGNACN AAYGCNAAYAAYGARGCNGTNGARGTNCARACNACNGTNCARAAYGARAAYGARGARATH YTNACNYTNGARGCNGCNYTNGAYTAYYTNYTNAARAAYGTNGTNAAYACN--------- ------AGYCARGARAAYGAYGGNGAYMGNGTNGTNCCNGTNGCNGARAAYTTYTCNCAR TCNTTYAAYTTYGAYAAYGAYGTNACNGARYTNCARCCNACNATHACNGCNGAYAGYYTN CARACNGARAAYGTNTCNCCNGCNCARAGYCCNCARGAYYTNGARCAYCAR--------- ------TGGTTYGARATGGAYCARTAYYTNAAYGGNACNGTNCARGARTCN--------- ------------CARCCNYTNCARGCNGTNGCNGCN------------------------ ---YTNCCNGCNCARGARCCNAGYCARGAYGAYGTNAAYGAYTCNCCNAARYTNGGNATG ATHGAYCCNYTNTTYAAYCAYCARGCNAAYGAYAAYYTNYTNCARAAYGCNTCNYTNCAY ACNACNGAYATGGARTAYTCNYTNGARTTYGAYAAYATGACNATGAAYAAYYTNAGYGGN TCNTCNYTNGARCCNATGACNYTNAAYYTNGAYTGGGAYTCNCARYTNGGNTGGGAYGCN GGNAAYGTNACNYTNTTYGAYAAYYTNACNACNYTNACNCARGAYCCNGCNGCNGAYGTN GAYYTNGARGGNATGGARGAYYTNTTYAAYAGYATG---------GAYAAYGCNTCNAAY YTNTTYACNACNTCNAGYAAYAGYGGNGAYATHTCNAAYATGATGATHTCNAAYGGNGCN GARGCNATGGTNATGCCNACNAARTCNTTYACN--------------------------- ---------GARGARYTNAAYGARACNTTYGAYGGNYTNGARGGNGCNACNGGNGGNGCN GAYTAYGAY------------------AGYCCNCCNYTNAARAARATHTCNMGNYTNTCN GARTCNTCNTCNGAYTCNGGNTAYAGY---AARGGNACNTTYAGYTCNTCNTCNTCNACN ---------TCNTCNTCNTAYGCNGGNAGYCCNGCNGAYAGYAAYATGATGAAYAAYGAR ACNAGYTCNAAYGAYACNGARCAYAAYCCNCAYGGNACNGARGCNYTNGCNCAYCARGTN GCNCAYAAYCAYACNTAYAAYACNYTNCCNGGNCAYACNCCNMGNGARGTNAARAARTAY GCNCAYAARGARCCNTCNAARAARGGNCCNCARTGYMGNGAYGCNMGNMGNGCNCARGAR YTNAARGTNCCNTTYACNATHGAYGARATHGTNAAYTCNCCNGTNGARACNTTYAAYGAY ATHYTNACNAARCAYACNYTNACNGARGARCARYTNACNYTNGTNMGNGAYATHMGNMGN MGNGGNAARAAYAARYTNGCNGCNCARAAYTGYMGNAARMGNAARGTNGGNGTNATHGTN ACNYTNGARGAYGARATGGAYGARYTNCARAARGCNMGNGAYMGNYTNMGNGARGARMGN GCNGCNATGGARAARGARACNMGNATGATGAARGAYAARTTYTCNCAYYTNTAYTCNCAY ATHTTYCARTCNYTNMGNGAYGARCAYGGNCARCCNTAYGAYMGNAAYYTNTAYTCNYTN CARCARTCNAGYGAYGGNAAYATHTTYYTNGTNCCNMGNAAYGTNAGYACNAAYGGNGAY ATGAAYGGNACNCAYAGYAAYGGNAGYAGYTCNGGNAAYGGNAGYAGYAAYGAYAGYGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CCNGTNYTNYTNATHTGGGGNTGYMGNGAYYTNGCNYTN GARACNGGNYTNGCNGARAGYTGYAARGCNTAYGCNTAYGAYYTNACNATHAARTAYYTN AARGAYGCNAGYCAYTGGGTNGARATGGAYGAYCCNAARCARGTNAAYGCNYTNATGAAR GARTTYATHAGY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGYTNAAYAARATHTCNACNTTY TGYMGNTTYGTNCCNMGNATGMGNAAYACNMGN---------YTNGGNCAYGGNGTNCCN GCNCAYTTYAARCCNYTNMGNCARGTNTGYGARGARAAYAARAGYCAYATGAAYTGYATG CCNATHCCNCARGGNTCNTGGCARGARGCNAAYAGYGCNMGNGCNTCNCARAAYAAYATG YTNYTNYTNGGNAGYYTNGCNAGYYTNATHGGNACNTTYGCNTTYYTNTAYGCNACNGGN ACNATHTAYTTYCAYGGNGCNCCNCCN---------YTNAARGAYAARAGYTCNAARYTN AARGTNCCNTCNMGNYTNGCNAARYTNGCNTCNGARAAYCAYACNYTNTTYGARAARTGY ACNACNGCNCARYTNGTNAARAARTCNCCNCARGCNGAYGCNGCNACNAAYTTYGTNAAR CAYYTNGARGARTCNAAY---GARATHAGYCCNGARYTNTAYGCNMGNGCNAARGCNYTN TCNTGYYTNCARAGYCAYAGYTTYATGATGCARACNYTNAARTCNYTNGARYTNCARAAR ATGTCNGARACNACNCCNTTYGARACNGCNTAYMGNGCNAARMGNYTNYTNGARTTYATH YTNTCNAARTTYGCNCARAGYCARAAYGARGTNGAYTAYTTYACNAARGTNCARTTYAAR TCNGCNGTNATHAAYCARGGNACNGARACNMGNCAYGGNAGYMGNAAYAGYGTNAGYATG GCNAARTCNYTNTTYACNAARCCNGAYGARAGYTCNACNACNAARCCNTCNGAYGTNMGN AAYGCNYTNACNTAYTCNAARTCNTGGAAYCAYYTNCARTTYGARAARAAYYTNTCNYTN YTNCAYCARCAYYTNATGACNYTNTCNCARGTNGARTGGYTNGAYGTNATHGCNCARCAR CCNGARGAYCARGCNATGGTNCARYTNGTNCAYAGYYTNYTNACNTCNAGYGGNCARTTY TTYTCNGCNGTNGTNAARAAYCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARGTNYTNAAR TCNACNCCNGGNGARGAYTAYGTNTCNTGYGTNGTNGARATHTAYMGNGTNTCNTGYMGN GTNATGGCNGCNATGMGNTCNACNGCNATHACNAGYGARGAYYTNGARCAYACNYTNAAR GAYATHGAYYTNATGTGGAAYAAYYTNTCNGCNTTYYTNGTNGGNGCNTCNYTNYTNCCN GAYCCNTCNTCNYTNTCNTTYTCNGAYGCNGTNGTNAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYTCNAGYATHGCNYTNGAYCAYTCNATHAGYGAY CCNATHAAYGAYYTNCCNGARCAYATHTTYGTNGCNYTNGARTGYYTNYTNGAYGAYAAY AAYGAYCARGTNCARAARGCNGCNGCNATHACNYTNTAYTCNYTNGAYMGNCCNTCNGAR AARGCNATGGGNMGNYTNMGNGAYATGYTNCAYAGYGAYAAYGCNATHGAYMGNTGGGCN GGNGCNCARTGYYTNGCNCAYTAYGGNGARTGYGAYTCNGAYGTNGTNGCNGARATHATH AARCARATHYTNGAYTCNGARTCNGCNATHAARCAYGARCARGGNATGGCNYTNYTNGCN AARATHAGYAAYAGYAGYACNYTNGTNCAYTGYATGGTNGCNGARCARYTNAAYAGYAGY AGYTGGMGNTAYMGNGTNATHGCNTGYAARATHYTNCCNACNYTNTTYGGNACNATHAAY MGNGAYATHACNCAYAARYTNTCNGARYTNATGTGGCAYGAYTGGCAYGTNGARGTNMGN AARGCNGCNGCNCARTGYYTNGGNAARACNAGYCAYGGNCARGAYGTNCAYGAYGAYATH MGNGAYMGNATHYTNAAYGGNACNGARMGNACNAARATGGARGCNATHAAYAARYTNGGN CARYTNGGNATHATGACNGCNAARYTNYTNCCNGCNTTYYTNYTNTGYTTYTCNGAYGCN TAYGTNTCNATHMGNTGYGARGTNTGYATHACNTGYGGNAAYYTNCARATHAARGAYGAR CARATHYTNGAYMGNYTNGTNCAYYTNGCNACNTTYGAYCCNATHTGGAARGTNAARGCN YTNGCNATHCARGCNYTNGGNAARATHGGNGARGTNACNGAYGARATHAARGARTGYYTN YTNTGGGCNATGMGNTAYGARGARAARCCNGGNGTNMGNGCNGARGCNTGYCAYTCNYTN GCNGARYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ACNTAYAAYGGNGAYGTNYTNGAYAARMGN TCNTAYTGYTTYACNGARCCNGARAARCCNTTYACNCCNMGNACNYTNAARAGYAAYCAY CARTCNMGNYTNAARAAYTCNAARAAYTAYAAYGCNCCNAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGGCNGCN TCNAGYTCNGAYGAYTTYATHATHMGNCCNYTN---AARGARGAYGARTGYAGYAARGTN GTNGARGARYTNGCNACNTTYGARAARATGCCNGARMGNGTNAAYATHACNCCNGARGGN YTNAARGARGAYGTNTTYGGNCARCCNCCNMGNTGYGCNTGYYTNGTNACNGARYTNCCN AAYGCNGGN------GARATHGTNGGNTAYGCNYTNTAYTAYTGGTCNTAYTCNACNTGG GARMGNACNTAYYTNCAYYTNGARGAYYTNTAYGTNAARCCNGARCAYMGNGGNAARGGN ATGGGNAARAARATGTAYCARACNGTNGCNCARGTNGCNYTNACNAARGGNTAYAARMGN YTNCARYTNGAYGTNYTNGGNTGGAAYAARCCNGCNAARGARTTYTAYGARAARATHGGN AAYCARGAYATGACNGARTCNGARGARTGGCAYAARATGMGNATGGGNCCNGAYGCNATG AARAARTTYATH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GCNCCNTCNAAYCAYGTNAARATHTAYGARGAYAGYAGYATH GCNGARAAYGGNCARAAYGTNMGNTGYTCNMGNGCNGTNCARACNGARGAYGTNYTNYTN GARGCNTAYATHCARCAYMGNCARYTNCARTGYGTNAAYGTNTCNACNGAYAGYGGNAAY YTNTCNGARTCNTTYGAYCARGGNGCNTTYGARYTNATGGCNAGYGAYAAYATHCCNGAR ACNTAYTGGAARGAYYTNGCNGARCARMGNMGNCARGCNYTNAAYGAYACNYTNGARGAR AAYAARAAYYTNTCNTTYGARATHGARACNYTNAARGARGARAAYMGNMGNYTNTCNGGN ATHGCNGCNAARGCNGARCARYTNGARAAYYTNYTNCARAAYGTNYTNTCNGAYGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATGCAYCCNTAYTAYTAYGTNCARTAYGTNCCNATHCCNYTNAARCARGAYYTNGAR ATGAARGTNAAYTGGGCNGCNTCNCCNAGYACNGCNCCNAARCARGAYACNAGYAARCAY CAYCAYGTNTTYGTNGGNGAYYTNAGYGCNGAYATHGARCARCAYCARYTNMGNGARGCN TTYGCNGGNTGYGGNGARATHTCNGAYTGYAARATHATHMGNGAYCCNACNACNATGAAR TCNAARGGNTAYGGNTTYGTNTCNTTYATHAAYAARCARGARGCNGARTAYGCNATHGGN CARATGAAYAAYCARTGGYTNGGNTCNMGNCCNATHMGNACNAAYTGGGCNACNMGNAAR CCNYTNGCNCCNGTNCCNAARGARAAYGCNAARCCNYTNGCNTAYGAYGARGTNTTYGGN CARTCNAGYTCNACNAAYTGYACNGTNTAYTGYGGNGGNGTNTCNAAYGGNYTNACNGAR GARGTNATGMGNAARACNTTYACNCARTTYGGNACNATHCARGARGTNMGNGTNTTYAAR GAYAARGGNTAYGCNTTYATHMGNTTYAGYACNAARGARGCNGCNACNCARGCNATHTGY TCNGTNCAYGGNACNACNATHAAYGARCARTCNGTNAARTGYTCNTGGGGNAARGARTCN AAYGARGGNAGYCARACNAAYCARCARTCNAAYAGYCCNCCNGTNGTNATGYTNCARTCN CARCARCARCARCCNYTNGCNGCNACNCCNGCNGCNGCNCARTAYGGN---CARTTYTAY AAYATGAAYTAYTAYCAYGGNACNCCNTAYGCNGCNGGNACNCCNACNTAYCARAGYGCN ATGCCNGCNCARGGNCARTTYATHCCNGCNGGNGCNGGNCARTGGCCN---CARTAYTCN AAYTAYCARGCNTAYGGNAGYATGAAYGTNCCNGTNGGNCARTAYGCNGGNYTNCARATG CARCCNGGNGCNCARCARCARCARTTYAGYGGNCARACNCARGGNATGGTNGGNTAYCCN ATGCARCARGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYTGYGARGGNGGNMGNYTNATGATGYTNGAY GGNGTNAAYGARACNACNATHGGNACNGAYGGNATGTTYATGTGYACNTTYTTYATHTCN TTYYTNTTYAAYTGGYTNGGNTTYYTNYTNTCNYTNTGYYTNTCNAAYACNATHGCNGGN MGNTGYGGNGCNYTNTCNGGNYTNGGNYTNTCNATHGTNAARTGGGTNGTNATHGCNAAR ------------------------------------------------------------ ------------------------------------------------------------ ------GTNCCNGARGCNCARAARACNYTNAARGTNAGYACNACNCARGTNGTNAARAAR GAYGCNTCNACNGARCAYTCNGTNYTNTTYYTNCAYGGNATGMGNTTYTCNTCNCARAAY TGGATGGAYATHGGNTCNYTNTAYCAYGTNGCNAAYTGGGGNTGGAARGCNGTNGCNGTN GAYYTNCCNGGNTTYGGNAARACNAARGAYACNYTNGAYGTNAARCAYAAYGGNTAYTTY YTNTCNTCNYTNATHTCNGCNYTNGGNYTNCAYAARCCNGTNATHGTNTCNCCNTCNATG AGYGGNTCNTTYTCNYTNCCNTTYYTNTTYGGNGAYGGNGTNAAYAGYYTNGAYMGNGCN YTNGGNTAYATHCCNGTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARAAYTCNTTYTAYYTNAAR GARATGGARGTNCARAAYAARAAYYTNYTNGAYTCNGTNAARAARYTNATGGAYGCNAAR GARGAYYTNGARACNAARGTNAARGAYYTNTCNTCNMGNYTNAARTCNMGNTCNGCNGAR YTNACNAAYCARACNYTNGARGTNTCNMGNYTNACNGAYCARATHAARYTNCARGARACN AAYYTNACNGARTTYAARGARGTNAAYMGNAAYYTNAARACNGARACNGTNGCNTGGAAR AGYMGNTAYTGYYTNTCNMGNGAYGARAGYGAYMGNYTNAAYGARGARAAYAARMGNAAR GAYGARCARATHCARACNYTNACNGTNCARYTNCAYGARACNYTNCARCARACNTCNGCN YTNCARAARGCNYTNTTYACNAGYTGYGAYMGNGARAARTGYAARGAYGARGTNATGACN TCNYTNAARAARCARMGNAARMGNACNATGCARGARATGGCNAGYYTNMGNAARYTNTAY GARATGCARTCNAARGAYYTNACNYTNTAYCAYYTNAGYGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TGG AGYAAYTCNTAYAARTGYTTYAAYTGYTGGAARTCNTGYTGYTAYAAYYTNYTNACNATH YTNTGYGCNATHCCNATHTCNATGTGYTGGGGNTGYGARTTYGCNTAYATHACNTTYACN CAYGTNTGGCARGTNACNCCNTGYATGMGNGCNTAYATGATHCARTGYGGNTGYATGCAR AARTTYTAYGGNACNTGYYTNCARTGYTGYATGCARCCNTGYTTYGARTCNATGGGNTAY TTYTTYAAYAAYATHAARGTNACNAAYGTNAGY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AGYAARTCNTTYTCNGARYTN GAYAAYYTNTCNGAYTTYTCNGCNTAYAARGARTGGMGNCCNMGNTCNMGNTCNYTNACN MGNAAYAARAGYTGGGCNAGYGAYGAYMGNGAYTCNACNCAYAAYTTYTCNGCNGTNACN ---------------GAYACNTCNCAYYTNAGYCARTCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TCNAAY TGGAAYCARGARACNAARTCNMGNYTNAAYGARAARGTNACNTCNAAYGTNAAYGAYYTN GGNTCNYTNATHMGNCARGTNATHMGNTCNTCNAARACNAAYGAR--------------- ------------------------------------------------------------ ---------------------------TTYYTNGCNCARGCNGCNAARGGNTGYTCNACN GARACNATGAARAARATGAAYGTNGTNAARTCNCARTCNTCNATHTCNMGNAGYGAYCAR YTNGCNACNYTN------------------------CARCAY------------GCNYTN GARTGGTAYYTNGAYACNGTNGCNMGNCCNAGYGAYCAYGTNYTNYTNTTYCAYTGYTCN CARTGGGARYTNCAYGTNGGNYTNCCNGGNATHGCNGTNAAYGTNGARCAYGTNAGYAAR CARGTNCARAARGCNAARGAYGAYGCNGARGCNATHATHMGNGCNGCNACNGAYATHYTN MGNCAYAARTCNATHCARTGYTAYTCNGTNATHGARCAYAARCCNAARCCNCAYGARGCN ATHYTNGANGTNATHGARMGNGARAAYGTNGAYTAYGTNGTNATGGGNACNMGNGAYYTN GGNACNGTNAARMGNGCNTTYGTNGGNAGYGTNAGYACNGARGTNGTNMGNCAYGCNCAY GTNCCNGTNACNGTNGTNAARCAYAARGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TCNMGNYTNGTNTGGATHGAYYTNGARATGACNGGNYTN GAYATHGAYAGYGAYGTNATHYTNGARATHGCNTGYYTNGTNACNGAYAARCARYTNAAY ATHGTNGCNGARGGNCCNGAYYTNGTNATHCAYCARACNGAYGGNGTNYTNAAYGGNATG AAYGARTGGTGYATHGARCAYCAYGGNCARTCNGGNYTNACNGAYGCNTGYMGNAAYTCN AARATHAAYACNCARGARGCNGARAARATGGTNGTNAAYTTYYTNGARCARCAYGTNAAY AARGGNACNTGYCCNATHGCNGGNAAYTCNGTNGGNACNGAYAARCARTTYATHACNAAR TAYATGCCNYTNYTNGCNGARCARYTNCAYTAYMGNGTNGTNGAYGTNAGYACNGTNAAR GARYTNTGYMGN---------------------------------MGNTGGTAYCCNGAR GAYTTYAARGGNACNCCNCAYAARAARYTNTCNCAYMGNGCNATGGAYGAYATHMGNGAR AGYATHCARGARYTNAARTTYTAYMGNGARAGYATHTTYAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYAARTAYGTNATHAGYGGN TCNGAYTGYGGNCAYATGTTYGTNTGGGARMGNYTNACNGGNMGNYTNGTNATGTAYYTN GARGCNGAYAARCAYGTNGTNAAYTGYGTNCARCCNAAYCCNCAYYTNCCNGTNATHGCN ACNAGYGGNATHGAYTAYGAYATHAARATHTGGTCNCCNYTNGCNGARGARTCNATGTTY GAYCCNGAYGTNGCNCAYTGYATHGTNCARMGNAAYGARYTNATGYTNGTNGARACNMGN GAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AARTCNTTYGARGARMGNAAY ACNTAYTAYGTNAARATHTCNTCNAARACNGAYAARGARAARAARCCNYTNATHTTYATH GAYGCNGGNATHCAYGGNMGNGARTGGATHTCNCCNGCNATGGCN---------ATGGAR ATHATHTAYCARYTNACNYTNAAYCCNGAYAAYGAYCCNGARGTNYTNYTNTCNAARTTY GAYTGGGTNATHGTNCCNGTNGTNAAYACNGAYGGNTAYGTNTTYACNTTYTCNMGNTCN YTNACNMGNYTNTGGMGNAARTCNMGNACNTCNGAYMGNCCNGARTGYTAYGGNGTNGAY YTNAAYMGNAAYTTYGAYACNTTYTTYGGNGGNAGYAGY------GAYCCNTGY---AGY ATGACNTAYTCNGGNCCNAGYAGYTTYTCNGARCCNGARTCNMGNAAYYTNMGNGAYYTN ATGATHCARAAYYTNCCNAAYATGAARGCNTAYTTYTCNYTNCAYGCNTTYGGNCARTTY TTYYTNTAYCCNTGGGGNTTYAGY---GGNYTNGTNGAYYTNGAYGAYGARACNGAYYTN CAYCARGTNGCNACNTCNTTYGCNACNACNATGMGNAARMGNGAYTAYGARTAYCAYGTN GGNGGNACNGCN------AARYTNYTNTAYCCNGCNGCNGGNGGNTCNGAYGAYTAYGTN AARGGNCARYTNGGNGTNAARTAYGCNTAYACNATHGARYTNCCNCCNYTNGARGGNTCN AARTTYGGNTTYYTNYTNCCNGARGARCARGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARTGYATHYTNGCNCCNGCNAAYTGGACNYTNTCNGARAARMGNATHAARTGYCCNACN MGNTGYATHATHAAYGCNMGNTTYGAYGCNAARACNYTNGTNCCNACNTTYTTYTAYMGN GGNTGYCARGAYACNAARGCN------AARGAYGGNTGYACNAARACNGCNGAYYTNTTY GARTGYATGTAYTCNTGYGGNGAYGGNGAYGAYTAYTGYAAYGAYAARACN--------- ------------------------------------------------------------ ---GARGCNTGYAARATGGCNGCNGARGGNATHGGNAARGAYTGGAARTCNGTNTAYTTY MGNYTNCCNTTYGAYCCNCCNMGNGAYCCNGCNMGNYTNCARMGNGAYGTNTCNGTNYTN GAYCAYATHGCNTTYMGNAGYGAYGTNCCNGARGAYAARCARGCNYTNAARTGYYTNCAR MGNTGGMGNACNYTNCAYMGNAARGGNGAYATHCAYGARYTNATHCARGCNYTNAARGAY GTNAARAARMGNAARYTNGCNMGNCARYTNTCNAAYMGNTTYGTN--------------- ------------------------------------------------------------ ---------------------------------------------ATHCCNACNAAYMGN ATHTTYCARCARYTNTTYYTNACNGTNYTNGTNCCNYTNYTNGTNGGNCARATGYTNMGN AAYTAYCARTAYCARTGGATHCARCARCARMGNATHCCNTTYGGNGAYATHGGNAARGTN YTNATHYTNTTYATHATHTAYACNACNTTYTGYGAYACNTTYTCNMGNACNGAYTTYCAR YTNAAYATGACNGARYTNATHGTNATHATHAGYYTNATHTTYGTNGTNCARATHGCNTTY ATGACNATHYTNYTNTAYACNAGYTCNGCNAAYTAYAGYGCNAARGAYTGYATHACNATH ATGTAYAGYGGNACNCAYAARTCNYTNACNYTNGGNATHCCNATGATHGARATHATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGTTYAARAARGARAAYYTNMGNAARAAYTTYYTNMGNGTN AARCARAAYATHGAYCARAAYYTNGGNMGNTCNGARAARTCNGARGTNYTNTCNGARGAY CARCARGARAAYGARAARMGNGTNGARGTNGTNAARCAYGCNTTYYTNAAYATHTGYAAR MGNACNGGNGCNATHGTNCARGCNCARGGNAGYGAYTTYGARAARMGNYTNAARAARYTN CCNGARACNGCNYTNGGNCAYGCNYTNYTNGARTCNGCNCARTCNYTNCAYACNGARTCN YTNYTNGGNCARGCNTGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGNTAYGTN YTNYTNGAYGARAARGGNGGNGARTAYCCNGCNGTNGTNGARTTYGCNCCNTTYCAYAAR GTNCCNAARMGNAARCCNAARAARGTNGAYTCNAARTGYGGNATHATHGARCARGAYACN GAYTAYAARAARTTYYTNGARYTNATHACNAAYCCNCCNGARGCNGCNCCNGTNTCNYTN GAYGCNATHGTNGARGARGTNGARGCNAARGARYTNMGNYTNGCNTCNAARGGNTCNACN AARACNAGYACNCCNYTNYTNGAYTAYYTNMGNMGNMGNMGNGARGARMGNMGNATGAAY AAYGTNAARYTNAARGARGARMGNAARMGNGGN------------------TTYGAYMGN MGNMGNTCNGGNAARGARGAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARACNATHMGNGGNGGNGGNGARATGTTYAARTTYCCNTGGACNACNTAY TCNAARYTNCARCARTTYCCNTTYAARTTYTAYTGGAARCAYGGNMGNYTNTTYMGNTAY YTNTTYTAYTCNTCNGTNYTNATHYTNCCNYTNATGGCNAARYTNACNAARGCNACN--- ------------------------------------------------------------ ---------------------------------------------------ATGCCNACN YTNGTNCCNGTNAGYGGNGCNMGNCARATHGGNGAYGAYCARCAYMGNTTYYTNGCNCAR CCNYTNGGNATHTCNATGCARMGNCCNGGNCARCCNTTY------ATHYTNGCNGCNCCN MGNYTNCCNCCNCCNACNGTNGTNGCNTCNTCNCARGCNAAYATGAAYGGN---GGNGCN CCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNGTNACNTAYAARGAYTGGAARTCNGGNAAR ATGMGNMGNMGNTCNATGCCNYTNMGNAAYTTYACNAARCAYAGYGGNGTNGARMGNGTN TAYGCNGAYYTNAAYGARAAYCCNMGNCAYGGNAARTAYGTNMGNYTNATHTCNCCNMGN CARYTNCARMGNYTNYTNACNATHATHAARGAYAARATHAGYGGNYTNAGYYTNGARGCN AGYGTNGCNMGNAAYAAYGARATGGARTCNYTNAAYCCNGAYGARAAYYTNAAYAARGTN GAYGARGARACNYTNAARMGNAARAARYTNGTNATGAAYTCNTCNTTYGARAARAAYCAR AARAARYTNGGNGAYCCNGAYTTYGARTAYAAYGTNGARGTNGAYTTYGAYGCNGGNGCN ATHGARACNTGYGGNTGGGAYTCNGGNGARTCNGAYGTNGAYTTY >crassicornis YTNYTNATHGCNCCNYTNYTNYTNGGNGTNGCNTCNGCNGGNTAYGAYCCNTAYACNGAY ATHGCNCARYTNTAYAARATGCARYTNYTNGCNGAYGCNTTYGGNGAYTAYYTNCCNGAR AAYYTNCCNGTNGAYAAYAAYGAYGTNGAR------ATHMGNTCNTAYTGGCCNGARTTY ---------------GCNGAYTCNYTNGARGAYGARGAYTCNGAYGAYGAYATGTAYGGN TCNCCNYTNTAYAGYGGNGCNCAYATHMGNGAYCARGARCAYATHGARCAYAGYGCNYTN CAYGGNTAYCARTCNGTNTCNGGNGGNACNGTNGARGGNCCNGCNAAYAAYAARATGCAR AARAGYGAYAARCCNYTNCCNGCNTAYTGYAAYCCNCCNAAYCCNTGYCCNATHGGNAAR ACNGCNAARGAYAAYTGYGTNGARAAYTTYGARAAYTCNGCNGAYAAYAAYAARAARYTN YTNAGYGARCARGAYTGYCCNTGYGAYACNGARCAYATGTTYAGYTGYCCNGCNGGNMGN GARACNGTNTCNTCNAARGGNAAYTCNGGNTAYCARCARACNYTNAAYAARGTNATHGAY CARYTNAGYAARATGGGNGCNGARGARGAR------GARAAYAGYGGNYTNYTNAAYCCN ACNCARAARMGNATHCCNATGGTNGCNAARAARTCNCCNCAYATHATHCAYAARMGNTCN GARMGNGCNAAYGAYGARAAYCCNTAYYTNCARGGNACNCCNATGGAYATHGCNGCNAAR AARGAYAGYGTNTCNTCNCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TTYATHGTN ATHGTNATHGCNACNTCNATHYTNATHATHACNYTNCARAARAARTCNAGYTGGMGNAAR ACNTCNGCNGGNAARGARTCNTCNTCNTCNTCNTCNGGNTCNAARGARACNAARATHTCN AARATGYTNACNATGGTNGCNTCNYTNTTYATHGGNTGYAAYATHCCNTGYACNGCNATH TTYYTNYTNTTYTAYYTNGAYCCNAGYTTYMGNATHCAYGGNGCNAAYGCNCAYTTYTAY YTNATGATGACNTAYATHTCNTTYYTNTTYGTNGGNATHAAYTCNAGYTTYAAYGCNYTN ATHTAYTAYAARAAYAGYTAYAAYTAYMGNGARGCNTTYGAYAARACNTTYGGNTAYATH AGYAGYATHTGYTTYYTNGCNGGNYTNATHCARGTNYTNTAYGGNGCNAGYATHGARGAY AARTAYGARCCNATGGTNGCNTTYATHTGYGAYMGNCCNGCNATGCAYMGNGGNATHAAY GGNTGGATHGCNGAYAARTCNCARGAYTGYCCNGAYACNYTNGARGAYGTNYTNGCNTAY TGYAARAARGTNTAYCCNGAYCAYAAYATHAGYAAYGTNGTNGARTCNTCNACNTTYTAY AAYATHTCNAAYTGGCCNATGGGNAAYGCNGGNMGNCARCAYACNCAYCAYGTNMGNCCN TTYMGNTGYYTNGTNGGNGGNTTYCARTCNGAYGCNYTNYTNGTNCCNCARCAYTGYGAR TTYGAYCAYMGNCAYGAYATHACNCARTGYAARGARTTYTCNCAYTGGAAYMGNGTNGCN GAYGAYGCNTGYGTNGAYAARGGNATGCAYYTNGARTCNTTYGGNATGYTNYTNTAYTGY AAYACNYTNGGNCAYTTYAAYGGNGTNGARTAYGTNTGYTGYCCNCAYAARACNGAYCCN MGNGTNCAYCCNGARCCN---AARAAYGCNGAYGAYAARCCNGAYAAYTGG---GAYAGY ACNGARGARGAYGARGAYGARGAYGARTAYGAYGAYAGYGAYGARGARTAYGAYTAYTAY TCNACNTCNACNTCNTCNTCNTCNAGYAGY------------------------------ ---------------GARGARTTYCCNGARGARAAYGTNGTNGAYYTNTAYGARGCNTAY YTNMGNGGNCARACNTTYCCNGCNCARTAYAAYAAYGARCAYAARAARTTYYTNGCNGCN AARGARMGNATGAARATGAAYCARAARAARAARGTNGCNAARYTNYTNCARGARTGGGAR AARGCNMGNGARCAYGTNAAYGARGTNMGNAARACNGAYCCNAARACNGCNGAYMGNATG AAYGAYGARATHGCNCARMGNTTYAARCAYYTNTAYGCNTCNTTYAARCARGARGAYGCN TCNGARAAYATGCARYTNGCNGCNYTNCAYCARCARCAYATHCARGCNTTYYTNAAYGAR AARAARMGNGARAAYATGGAYMGNTAYATGAAYGCNYTNGARAGYGGNAAYACNGCNATG GTNAARAARTAYYTNCAYAGYTAYATHAARGCNGARGARAARGAYMGNATGCAYACNGTN AAYCAYTTYGARCAYATHMGNAAYTCNAAYCCNAARGARGCNYTNMGNGTNCAYMGNCAY ATHATHAAYCAYYTNAARYTNTCNGARATGMGNATHGAYCARGCNATGGARATGYTNACN CAYTAYCCNGCNGTNGARAAYGARGTNMGNCCNGARATHGARGARTTYYTNAARMGNTTY AAYGARATHGCNACNAGYATHAARAAYGTNGTNYTNCCNGTNCCNGARGTNGAYAGYCAR GARGAYACNAGYGCNAGYAGY---------------GAYTCNGAYAGYAGYTAYACNACN TCNAAYGAYATHAGYTTYGAYGAYAAYACNAARTAYGAYACNAGYAGYGARCARCARGAR GARACN---------------------------------------GGNAARGARGCN--- ---GARTCNGAYTCNGGNATHATHGAYGAYGARGTNCARGARGAYGARCAYAGYTAYGAR MGNGAYGAYCARTTYGCNGCNAAYGCNCARTCNGAYACNCARAGYGCNAAYCAYGGNYTN CAYTCNGTNGCNAGYTCNGGNGCNCARATGGGNAGYACNATHGGNATHGCNYTNGGNAGY GTNAGYGTNTTYGTNATHGTNATHGTNGCNGTNATGATGGTNMGNCAYAAYAARAAYMGN CARTCNGTNTCNCAYGGNTAYGTNGARGTNGAYCCNTCNGCNAGYCCNGARGARMGNCAY YTNGCNAAYATGCARATGAAYGGNTAYGARAAYCCNACNTAYAARTAYTTYGAR------ ---AARGAYAARYTNTAYMGNCARATHACNGTNGARGTNAARGGNCAYGAYCCNGCNGTN YTNAAYAGYTAYCARAARTTYACNACNYTNGCNGCNGARAARYTNGGNGTNAAYYTNGCN AAYGTNTCNGARCCNCCNAARGTNTTYACNMGNMGNAGYYTNYTNAARTCNGTNTTYATH TTYAARAARCAYCARCAYCARTAYGARAAYGTNACNYTNTTYMGNGARTTYGARTTYAAR CAYYTNACNGARTCNACNGCNYTNACNTTYYTNGARTAYATHCARMGNAAYYTNCCNGAR GGNATGGCNATGAARGTNACNAARCAYGARYTNCAYTCNYTNCCNGAYCAYYTNAARCCN CCNAARCARTCNCARCCNTCNGCN------------GAYTAYTTYAAYGTNATGYTNGGN ACNCARYTNYTNTAYAARTTYGARMGNCCNCARTAYGGNGARATHYTNGCNGARAAYAAR GAYAARCCNATGTCNAGYATHTAYGGNGCNACNCAYYTNYTNMGNYTNTTYGTNMGNYTN GGNGCNATGYTNGCNTTYACNTCNYTNGAYGARMGNACNGTNCAYATHYTNYTNAAYCAY GTNCAYGAYTTYYTNAARTAYATHTCNAARAAYGGNGGNACNYTNTTYAARACNTCNAAY TAYGARATHGCNACNCCNGAYTAYCAYMGNAARGCNATH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATHGAYATH ACNTAYTTYCCNTTYGAYGAYCARATHTGYGARYTNAARTTYGGNTCNTGGACNTAYGAY GGNTTYCARGTNGAYATHACNAAYMGNTCNGCNACNGTNGAYYTNCARAAYTAYGTNYTN AGYGGNGARTGGGARYTNGTNAARGTNGGNYTNAARMGNACNGARGTNACNTAYGCNTGY TGYAARGARCCNTAYCCNGAYGTNMGNTTYACNATHGTNATHMGNMGNAARACNYTNTTY TAYYTNTTYAAYATHATHTTYCCNTGYYTNTGGYTNACNATHYTNAGYYTNYTNGGNTTY TGGYTNCCNCCNGAYTCNGGNGARAARATHACNYTNGGNATHACNGTNYTNYTNGCNTTY TCNGTNTTYATGYTNYTNATHGCNGARAGYATGCCNGCNACNTCNGAYTTYGTNCCNYTN ATHGGNATHTAYYTNACNGTNACNATGGGNATGACNTCNYTNTCNATHATHYTNACNGTN TTYGTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TCNAARCARMGNTGGATHCCNYTNGAR TCNAAYCCNACNACNYTNAAYAARTAYGTNCAYGGNYTNGGNATGGAYAARTCNTGGAAY TTYGTNGAYGTNTTYGGNYTNGAYCCNGARYTNYTNGCNATGGTNCCNMGNCCNGTNGCN GCNATHGTNYTNYTNTTYCCNGAYATHAARACN------------GARAAYGCNATHGGN GARTAYATGAARGARTCNCCNGARGAYYTNTAYTAYACNAARCARACNATHGGNAAYGCN TGYGGNACNGTNGCNYTNGTNCAYGCNYTNGCNAAYAAYCARGAYMGNATHACNTTYGAY GARAAYAARGCNTTYTCNAAYTTYYTNAARGCNACNAARATGATGAAYCCNGARGAYAAR GCNAARCAYYTNGARCARGAYATGGARATGGGNGCNGCNCAYGARGAYTGYGCNCARGAR GGNGAYACNGCNGCNCCNGCNGCNGCNGAYAARGTNAARTGYCAYTTYATHGCNYTNGTN CAYTTYAARGGNAAYYTNGTNGARYTNGAYGGNTGYAARGARGGNCCNGTNTCNCAYGGN GARACNACNGARGAYAAYYTNYTNGARGAYGCNGCNGTNGTNGTNAARAARTTYATHGAR AAYAGYCCNTAYGAYGCNGAYMGNCARYTNYTNYTNAARAARGAYCARATGACNGTNATH GGNTCNAGYYTNTCNYTNGAYACNGCNGARCARTAYGTNTCNGAYGCNATGAARAARGAR AARACNACNYTNATGGARAAYAGYMGNCAYAARMGNGARGAYTAYTCNCCNTCNTGGAGY TTYTTYMGNTCNAARCCNATHATGGARMGNACNATGYTNTTYAARYTNATHACNATGATG CCNAARGGNGCNGCNYTNCAYYTNCAYGAYATGGCNATHACNAGYYTNGAYTGGGTNGTN AARAAYGCNACNTAYMGNAARGAYYTNTAYATGTGYGTNAAYAGYGAYCAYYTNATGYTN TTYAARTAYTCNGCNAARAARCCNACNAARGAYTGYGAYTCNTGGAAYTCNGTNGCNCAR GARMGNTCNATGGCNAARAGYGTNAAYGTNTTYGAYGARAAYATHAARAARAAYYTNAGY ATGYTNAGYACNGAYCCNYTNGTNACNTAYCCNACNATHACNCARGTNTGGGAYMGNTTY ATGGGNTAYTTYGGNCARGTNGGNCARATHATHTTYTAYAARCCNGTNTTYMGNGAYTAY TTYTGGCARGCNYTNCARGARTTYCAYGAYGAYAAYGTNCARTAYATHGARYTNMGNGGN YTNATGAAYGGNATGTAYGAYYTNGCNGGNACNGCNTAYACNMGNAARGAYATGTTYGAY ATHTAYATGCARGTNGCNAARGARTTYACNGAYAGYCAYCCNGGNTTYACNGGNGCNAAR TTYATHATGTCNGGNATHMGNGTNTTYGCNAARTCNGARATHYTNAARGARATHAARGAR ACNATGGAYATGMGNGAYAARCAYCCNGAYTAYATGYTNGGNTAYGAYYTNGTNGGNCAR GARGAYCCNAAYTAYTCNYTNYTNCAYTAYMGNGAYGARYTNYTNTAYCCNGGNCARYTN AGYCCNCCNAARAARYTNCCNTAYTTYTTYCAYGCNGCNGARACNAAYTTYCARCARGTN GARACNGAYTAYAAYYTNATHGAYGCNATHATHYTNAAYACNACNMGNATHGGNCAYGGN TAYGCNYTNGGNAARCAYCCNCAYYTNATGGARATHATHAARACNMGNGAYATHGCNGTN GARGTNAAYCCNATHTCNAAYCARGTNYTNGGNYTNGTNAARGAYCCNMGNAAYCAYGCN GCNGTNCCNYTNYTNGCNGAYGAYTTYCCNATHGTNATHAGYTCNGAYGAYCCNGCNCCN TGGGARGCNAARCCNYTNTCNAGYGAYTTYTAYGTNACNTAYATGAAYATGYTNGGNGAR GAYTCNAAYYTNAARAGYYTNAARCARYTNGCNATHAAYTCNATHAARTAYAGYGGNATG AGYGGNGTNGARAARGCNGCNGCNATGTCNAAYTGGGARGTNYTNTGGAARAARTTYATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GARAGYGAYAAYGARAARMGNAAYATGAAYACNYTNMGNYTNGGNAAR MGNCARATGAGYTCNYTNGGNCARGAYAGYAARMGNTTYCCNATGYTNMGNGTNGGNAAR MGN---------GARAGYGARGAYGARAARMGNAAYYTNAAYATGYTNMGNYTNGGNAAR MGNCARATGAAYATGYTNMGNYTNGGNAARMGNCARATGAAYATGYTNMGNYTNGGNAAR MGNCARYTNAAYATGYTNMGNYTNGGNAARMGNCARYTNAAYATGYTNMGNYTNGGNAAR MGNGAYGCNGAYGAYAAYACNGCNGCNAARMGNAAYYTNCARATGYTNMGNYTNGGNAAR MGNCARGARGAYGAYGTNGARAARMGNAAYYTNCAYATG--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CAYGARGARGTNYTNAARATGATGAARCARATHCAYGARATGTGYCCNAAYATH ACNMGNYTNTAYAAYYTNACNGARCCNTCNGTNCARAARMGNAGYYTNACNGTNYTNGAR ATHACNGARAAYCCNGGNGTNCAYAARCCNGGNAARCCNGARTTYAARTAYGTNGGNAAY ATGCAYGGNAAYGARGTNACNGGNAARGARATGYTNYTNTAYYTNATGYTNGCNATGTGY GARGARTAYACNAAYGGNAAYGAYYTNGTNMGNTTYATHGTNAARGARACNMGNGTNCAY ATHYTNCCNACNATGAAYCCNGAYGGNTGGAAYGCNGCNAAYGARTAYMGNAARGARCAY GGNAARTCNGAYTGGYTNACNGGNMGNGCNAAYGCNAAYAAYGTNGAYYTNAAYMGNAAY TTYCCNGAYYTNAAYGCNAARATGTAYGARAAYGARAARGARCARMGNGGNMGNAAYAAY CAYYTNGTNAARGTNGARAAYGCNATHGARAAYGAYAARTCNYTNCARCCNGARACNMGN GCNGTNATGMGNTGGYTNGCNAGYATHGGNTTYGTNYTNTCNGCNAAYYTNCAYGGNGGN GAYYTNGTNGCNAAYTAYCCNTAYGAYGARACNMGNTCNGGNAARCCNCARGARTAYACN TCNTGYCCNGAYGAYCAYACNTTYGTNTTYYTNGCNAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYGAYMGNTAYAARCAYATHCAYAAYGCN ATGTAYTAYGAYYTNTGGATGACNACNAARAARGCNYTNTTYTTYATHGCNTCNGTNTGG ATHYTNTCNATHYTNATHTCNTTYYTNCCNATHCAYYTNGGNTGG--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNTCNATHAAYATGTTYYTNGARAARATGTAYYTNATHYTNTGGTTYTGGYTN ATGATGATGYTNGTNTTYAAYTCNGTNAAYYTNYTNCARTGGYTNTAYMGNGGNATGGTN CCNAGYAARGGNGAYGAYTTYATGMGNAARTAYYTNYTNYTNYTNGGNATHGAYTCNAAR TCNCARMGNAARYTNTTYATHAARTTYGTNMGNAARTAYYTNMGNACNGAYGGNGTNTTY ATGYTNMGNATHGTNGCNTCNAAYACNAGYGARATHYTNACNACNGAYYTNYTNAARCAR YTNTGGATHAARTTYAARGTNGTNCAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------AGYYTN GTNTCNTGYYTNCCNAARMGNTCNGCNGARGAYATHYTNCARGAYACNTCNGGNATGGTN YTNGAYAARMGNCCNAARTAYATGGAYACNMGNMGNGAYYTNGAYGTNTTYAARGAYYTN GTNYTNATGAGYYTNCARGARYTNGTNGAYGARGGNMGNYTNGARCCNTCNACNYTNCCN GARGAR------GAYMGNGARACNAGYAARCCNGTNGARAARMGNMGNTAYATGGGNYTN TGYATGCAYMGNCARGCNAAYCARTAYATHCCNTTYCCNTGYYTNMGNACNGGNMGNATG AAYGCNGTNYTNTGYYTNYTNYTNATHGGNTGYGCNACNGTNYTNGCNGAYAAYTAYYTN TGYCCNCCNNNNGANGGNNNNGARTTYNNNTGYTTYGARTCNGAYCCNNNNNNNNNNGCN TGYYTNACNGAYGGNMGNMGNGGNGAYGCNTAYGTNGTNTGYTCNAARTGYAARMGNAAR TGGGARTTYTGYGTNACNCAYGGNNNNTTYCARGARTCNAARAAYCCNGARMGNGAYTGY GGNGCNGAYTAYNNNAGYACNNNNTGYNNNCCNGARAAYTCN------------------ ------------------------------------TAYMGNCCNTAYMGNACNTTYATH CCNAAYGGNYTNYTNGTNCCNGAYCCNTGYAAYCCNGAYTCNATHTGGCARGGNGTNGGN CAYYTNAAYTCNCARGGNGGNGGNGTNMGNAAYCCNTTYGGNACNGAYTTYGCNAAYGCN GGNCAYCARTGGACNGTNGCNYTNTGYCARCARGAYTCNGAYGGNGAYGGNYTNTCNAAY GGNGTNGARYTNGGNGAYCCNGAYTGYACNTGGACNMGNGGNAARACNCCNATHCCNACN ACNGGNYTNTCNCAYCCNGGNATHAAYAAYACNACNCCNGGNTGYGTNAGYACNATHATG TCNAARCCNTAYGTNMGNGARTAYGAYAAYMGNMGNTAYGARGGNTTYYTNAARGARYTN YTNGAYYTNATHTCNAARMGNGCNGGNTTYGAYTAYMGNTTYGTNGARCCNGAYMGNMGN GTNTAYGGNTCNGAYACNTCNGARGGNTGGACNGGNGTNATGGGNGAYGTNTAYTCNGGN GTNGCNTCNATHGGNGCNCCNYTNACNGTNACNCCNGARMGNGARAAYGAYGTNGAYTTY ACNAARCCNTTYATHGCNGAYGGNGTNAAYYTNYTNGTNMGNAARCCNACNTTYTTYGAY YTNGGNYTNGGNTAYYTNGTNMGNCCNYTNTCNTCNGAYTTYTGGATHATGYTNATGGTN GTNYTNYTNYTNATHGGNYTNGTNTTYTTYATHATHGGNAARTTYAGYCCNTAYGARTGG GGNAAYGTNGCNGCNGAYMGNGAYCCNMGNGGNGCNMGNAAYAGYTTYACNYTNAARAAY AGYTAYYTNTTYGCNTTYACNACNYTNTCNTGGCARGGNTTYMGNGARGCNCCNAARTCN ATHTCNGGNMGNATHATGGCNGCNTTYTGGYTNYTNTTYGTNYTNTTYACNYTNATHGCN TAYTCNGCNAAYYTNACNGCNTAYTTY---YTNGCNMGNCCNGARCARATHCCNAAYTCN TAYGARGARYTN---YTNGARTCNGAYATHMGNGTNATGGTNACNGAYTTYAGYTCNACN GARTCNTTYYTNMGNAAYAGYMGNAGYCARACNYTNMGNGARYTNTGGGGNAARATGTCN AGYACNGGNGCNATHGTNCARACNGARAAYGARGGNATHACNAARGTNMGNTCNGAYGGN GCNGAYTAYGCNATGTTYATGGARACNAARAARGCNGARTAYACNGCNATGAAYAARGAY TGYAARYTNYTNGTNTAYGGNGARTCNYTNTTYCCNAGYACNCARGCNTTYGCNGTNGCN AARGGNTCNGCNTGGMGNGAYATHATHAGYGARAARATHGARGARYTNMGNACNAGYGGN YTNYTNGARGARYTNAARAAYMGNTAYTGGAARTTYGGNGGNMGNTGY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNGTNACNYTNAGYYTNYTNGCNGGNAGYACNTGYGCNGTN TTYTAYATHCCNGGNTCNGTNGTNAGYTAYCCNAARATGGGNAARMGNGCNTTYTAYACN AAYGCNACNGGNAAYMGNTAYCCNYTNATGGGNMGNMGNACNTCNCCNGGNCARTCNCAR GGNCARAAYGCNGARATGGCNGCNGTNGCNGCNGGN---GCNYTNGTNCARAAYGGNGAY GARTTYAAYAARMGNGGNGTNTTYACNAARGGNCCNCAYMGNAGYTTYCCNMGNGTNGGN MGNTCNGAYGCNTCNAGYGAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAY CCNYTNAAYATGTCNGTNGAYYTNAGYYTNGTNAARATHAAYAGYGTNGAYACNGARACN AAYGTNGTNTCNATHGAYGCNTGGATHACNTAYAGYTGGAAYGGNGGNATHAGYTTYAAY CCNGARGAYTAYAAYAAYGTNACNCAYGTNMGNYTNCCNAGYTCNAARATHTGGYTNCCN GAYYTNACNGTNTAYAAYGGNGAYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTN GTNGTNTCNTCNTCNGGNCARGTNACNTGGGTNCCNCCNGTNAARATHMGNYTNTCNTGY AAYATGGCNGAYNNNNNNNNNNNNNNNAAYAAYACNTGYATHATHAARATGGGNTCNTGG GTNTAYTCNGGNYTNGAYYTNACNYTNGAY---GARACNCCNMGNTTYGAYYTNAGYGAR TAYGGNATGCAYCCNAGYTAYGARGTNYTNGAYGTNTCNGCNAARAARCARACNAGYMGN TAYGCNTGYTGYCCNGARACNTAYGARAAYATHAAYTTYTCNYTNACNTTYMGNGARMGN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYYTNGTNGGNYTNGCN GCNYTNYTNATHTCNCAYGCNCCNTCNACNTGGGCNAAYTAYGARCAYTTYTGYAGY--- TCNGCNGAYTTYGARTAYCARMGNGGNGTNTGYGGNGAYGGNYTNGTNAAYACNATHAGY ATGGCNTGYCARTTYYTNAAYMGNAAYAGYMGN------GGNAARTAYYTNGTNAARMGN AGYYTNCCNAAYGARATHGAYMGNCARATHMGNGAYYTNYTNGTNGARAARAARGAYGCN TTYTCNTTYYTNTCNAARMGNCARAGYAGYCARAAYATHATHTGYGARTGYTGYGTNAAY AGYTGYAAYATHATGGARYTNTAYCARTAYTGYGARYTNCCNAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GCNAARYTNAARAAR---AGYGGNGGNAAR YTNGTNTAYGAYMGNGCNTAYYTNATGGARYTNMGNGARTGYGCNTCNTCNCARGCNAAR CCNGAYGGNYTNCCNGCNYTNGARATHATHYTNGAYCARCCNAGYCCNTAYATGTCNMGN ACNTCNYTN---GGNCCNGCNGAYTTYACNCCNGCNTTYTTYCARACNGGN---GCNAAY CARMGNCAYGCNCCNCCNATHGGNAARAGYAGYAGYMGNGGNMGNCCNMGNCCNGGNGAY ATGCCNGGNACNCCNMGNGTNATHAARAGYATHTCNATGTCNAAYGAYACNAARCARYTN CAYCARAGYGAYAAYCCNTGGAAR---------CCNACNAARAARGAYGARAARGAYGAR AARATGACNTTYGARGGNAARATHYTNTTYATHATGAAYMGNYTNACNCCNACNAAYTTY GARAARYTNGCNGCNGARATGAARGGNYTNAGYATHAARACNTAYGARGAYYTNCARTTY ATGGTNAARGTNTTYTTYGAYAARGTNACNYTNGARACNAARTTYGTNGARGCNTAYGCN CARYTNTGYAARGTNATGTCNGGNYTNAARGTNCCNCCNCCNACNGAYGGNACNGTNAAR GARAAYATGGCNACNTTYMGNGTNGTNATGYTNACNAARTGYCARCARGARTTYGARGCN GAYAARTCNATHATHTTYGARGAYCCNGARGARAARMGNMGNAARYTNGCNGCNGARAAY TCNGAYCCNGCN---GARMGNGAYGTNYTNATHGARCARACNYTNTAYCARATGAARYTN AARMGNATGAARTTYTAYGGNAAYATHMGNTTYATHGGNGARYTNTTYAARYTNGGNATG YTNACNGARAGYATHATGCAYGAYTGYATHTAYMGNYTNYTNAARGCNMGNGAYGAYGAY TCNYTNGTNTCNYTNTGYAAYYTNYTNACNACNGTNGGNMGNAAYYTNGAYACNGAYAAR GCNMGNCCNMGNATGGAYCARTAYTTYTCNCARATGTCNAARATHGCNGAYGARMGNAAR TCNMGNATHAARTTYACNYTNMGNGAYGTNATHGARYTNMGNCARAAYAAYTGGATHCCN MGNAARCARGCNACNGGNCCNAARAARATHGAYGARGTNCAYAARGAYTTYGCNCARGAR CARYTNMGNAAYCARTAYYTNGCNTCNCARCCNCCNCCNCCNMGNAAYGAYAAYTCNCAR GCNGGNAGYMGNMGNGGNAGYMGNCARMGNCCNGAYGARACNAARATGGGNGARGAYGGN TGGAAYACNGTNGGNAAYCCNAARTCNTTYMGN---ATHGAYGCNTCNAARATGAARATH TCNTCNAARAAYGTNGTNGAYGAYAAYATHCARYTNGGNCCNGGNGGNGGNGCNAAYMGN ---CCNATHTGGAGYMGNGGNAGYCAYGGNGGNACNCARCARCCNAAYCCNGAYGAYMGN CCNGCN---YTNGGNAAYMGNTTYTCNGCNYTNACNAGYGAYGAYGCNMGNMGNTCNTTY CCNMGNTCNCCNTCNMGNGGNGARGGNTCNGCNGGNMGNAGYYTNMGNCARGGNCARTCN GCNGGNCAYGGNMGNGGNAARATHATHTCNMGNTCNAGYCARGAYGGNGARMGNMGNGAY GCNATHGCNAAYACNMGNTCNTTYATGGGNGGNMGNTCNCARAAYTCNAGYMGNGAYAAY AGYTGGAAYMGNGAYGAYMGNMGNCARATHACNGGNCCNMGNAGYTCNTGGGARMGNGAR AAYCCNATGACNMGNAGYGAYAGYGCNGTNMGN---ACNGARGARTTYAARACNCCNGCN CCNCCN------GCNGTNAARCARATGTCNGARTCNGARGTNGARACNAARGCNGTNAAY ATHYTNGAYGARTAYYTNAAYATHMGNGAYYTNTCNGARGCNAARYTNTGYATGAARGAR YTNGGNGGNCARAAYCAYATHCAYYTNGTNGTNACNGCNAGYATHAAYAAYGTNYTNGAR AARMGNGAYGARGCNMGNCAYATGACNGGNACNTTYTTYAAYGARYTNGTNAARAGYAAY ATHATHTCNYTNAAYTCNTAYATHAARGGNYTNAAYGARGTNYTNGARTAYGCNAGYGAY ATGGTNGTNGAYATHCCNACNYTNTGGAAYTGYYTNGCNCARGTNATHTCNCCNYTNYTN GTNGGNGGNACNYTNCCNTGGTCNAARYTNAARCARGCNTTYTCNCCNCAYYTNAAYAAY MGNGAYGGNGCNAARYTNATGGCNTTYYTNYTNTCNCAYTCNGTNGARATHCARGGNGAR AARGARATHTCNAARGARTGGCARAAYAGYGGNYTNAGYTGGTCNACNTAYYTNAARGCN GAYGARYTNAAYTCNTTYGTNGCNGAYAARAAYYTNGGNTTY------------------ ------------------------ACNYTNGGNGCNCCN---------------TCNGGN GAYGTNGARAARATGATHTGYAGYMGNGCNTCNAAYAAYGARYTNGTNTCNTAYATHGAR AARACNGTNCCNGGNAGYAARAARGAYTCNAGYTTYATHMGNGCNYTNACNACNGCNGTN GTNAGYGCNTCNATHAAY---------GARAAYAARAAYATHAAYGTNGAYGTNATHAAR AAYAAYAARGAYATHYTNCARMGNTAYYTNGGNAAYGCNGTN---GAYYTNCARYTNCAR GCNYTNTAYGCNATHCARACNYTNATGGTNAARYTNGARCAYCCNTCNGGNGCNYTNAGY AARYTNTTYGARYTNYTNTAYGAYGARATHTCNATGGARGARGARGCNTTYTAYAARTGG GARAARTGYAAYGAYCCNCARGARCARGAYGGNAARGGNTCNTGYGTNATGCARGTNMGN CAYTTYTTYATHTGGYTNMGNGARAAYGARGARCCNGAYGCNGARTCNGGNTTYGCNGGN GAYGTNGAYTTYATHACNAGYCCNGGNYTNAAYGCNCCNGTNGCNGAYYTNGGNATGAAY GAYCAYCAYCARYTNTAYGGNACNACNGGNGGNAAYGAYAGYTGGTTYGAYGAYYTNGAY CCNGAYYTNTCN---GGNGAYCCNYTNGGNGAYGAYAGYATGGARGCNTTYATHAAYYTN GAYAARTTYYTNAAYGGNAAYTCNTTYTTYGAYGAR------GAYGGNAAYYTNACN--- GTNCCNGARGGNGCNGARGTNGCNCCNGTNATHAAYTTY---GTNAAYGARACNGGNGCN GGNAGYYTNAAYACNGGNATHGARGGNGGNGAYCARGAYTTYYTNYTNTCNCCNGGNACN MGNTCNTCNMGNAARMGNCCNGCN---GGNTCNMGNGGNGGNYTNACNACNAGYYTNTAY GARATHCCNGCNMGN---------------GGNGARGARGARGGNTCN------GCNYTN ACNYTNTCNGAYACNGARYTNGAYCAYGAYTAYAGYACNAARMGNCARMGNATGCAY--- ---------------GARCCNACNGGNAAYAAYAAYAGYACNCCNTCNTCNACNAGYGGN ACNATGGGNGCNGGNMGNAGYTTYGAYGCNGCNAGYATHATHCCNCARACNGTNGTNATH GCNTCNGTNGAYGAYGGNAAYTGYCCNGTNGAYAARCARACNATHMGNMGNATHAARAAY AAYCAYGCNTCNAARMGNTCNMGNGARCARMGNAARCARAARTTYGTNGAYATGGAYACN GARGCNGAYGARYTNGTNGTNMGNAAYGAYMGNYTNMGNGARAARATHGTNGARYTNGAR AARYTNGCNAARGARATGAARGCNGTNYTNGTNGCNAARATGGCNGGNAARGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARAAYGARGARGAYGGNACNGAY TCNGCNGAYTCNAARGTNTCNTCNTCNTTY---------GTNGCNCAYGCNMGNCCNTAY TCNGAYTCNGCNGCNTCNGCNCARGAYGGNAAYCARGARGTNAGYAGYTCNGAYATHACN GARTCNTCNCAYCCNCCNAARGTNCCNGGNGCNTCNTCNATGAGYCCNTAYAGYAGYAAY GCNTTY------TAYGGNAAYACNCAYAAYGCNGGNATGTAYACNAAYCCNTTYGTNCCN MGNGCNCCNYTNAARTCNGAYGTNGTNTCNTCNAAYAGYAGYGARAGYMGNGAR---GGN GCNGGNYTNATHGCNCCNAGYMGNYTNAAYGCNGCNGTNAAY---AAYMGNGAYAGYTCN GARGTNGARGGNAAYMGNTCNTTYCCNAARCARTCNGTNYTNGCNCCNCCNAARYTNACN GGNGCNGTNTTYGGNGGNGGNAGYGCNAGYCAYGAYACNCCNAGYTCNACNTTYAAYTCN TTYAAYTCNTAY---ATHMGNCCNTCNGTNTTYTCNGGNCCNTTYGAYTCNAGYMGNGGN GGNGCNACNGCNCCNYTNYTNAARCCNGCNAARYTNCCNGAYCCNACNAARTCNTGYGAY AGYAARGCNGAYTCNGCNAGYGARGCNGAR------GTNYTNAGYGCNAAYGCNAARTCN GGNGARGCNTCNTCNGCNAGYGAYMGNYTNAGYGGNGCNGAYGGNACNTCNGGNGGNAGY GARGTNTCNTCNTCNTCNGCNTCNTCNTCNYTNCCNCCNCCNGTNCCNCARCCNATGCCN GAYGCNGARGGNGCNGTNGGNGGNGARAAYACNCCNTAYAAYCARGAYATHGTNCCNGAY ATHAAYAARAAYAAYMGNYTNAARGAYACNTCNGGNGTNTCNAGYAGYTCNCARTCNTTY GTNTTYGGNAGYAAYYTNCAYCARMGNGTNACNGGNATHYTNTCNTCNCCNGTNATHGAR AAYGARGCNTCNGCNTCNCCNGGNTTYGTNTTYGGNGARTCNYTNGGNTCNMGNGCNGTN GTNGARACNAAYGGNGCNGCNYTNCCNCAYAARGAYGAYGARAGYGAYTCNGAYTCNGGN AAYAARGCNAAYCARACNYTNGARGARTCNGCNMGNGARTAYCARGCNAARCAYGAYATG MGNACNGARYTNGCNGARGTNGARACNATHACNGGNGARGARGARGARTCNAAYGTNYTN CARGCNAAYGGNAARYTNTTYTTYTTYGARACNAGYAAYGARTCNTGGGTNGARMGNGGN MGNGGNAGYATHMGNYTNAAYGAYATGTCNGCNMGNGAYGARACNAAYTTYCARTCNMGN YTNGTNATGMGNACNCARGGNAGYYTNMGNGTNGTNYTNAAYGCNAARATHTGGCCNGGN ATGTCNYTNGARMGNGCNTCNTCNMGNTCNATHMGNATHACNGCNATGGAYACNGAYGAR TCNATHAARATHTTYYTNATHACNACNAAYGTNAARGAYTCNGARAAYYTNYTNMGNGCN ATHGAYTGGMGNATHCARCARYTNAARATHCARGARGAYCCNGTNMGNCARCAYTCNGTN TCNMGNACNGGNGAYAARMGNAARGCN---GAYTCNGAYTTYGARYTNCCNGTNAARAGY AARAARGTNAAYAGYTCNCCNGAYCARGGNATHTCNATGACNAARAARGARGARTCNGAY AGYAGYGTNCARGAYCCNGARACNGARGCNTCNTGYGARAGYCAYTCNTCNTCNYTNACN ATHAARTCNGARTCNGAYTTYCARTGYATHCAYTGYGGNTGYGARAGYGARAARYTNTAY CAYGAYTTYAARGCNGGNATHACNAARGTNACNAAYTGYAARGCNTGYGGNAAYATHGTN GAYAARTAYGTNGARTAYGAYTCNGCNATHATHYTNYTNGAYATHYTNYTNYTNCAYMGN CARGCNTAYGCNCAYYTNYTNATHAAYGTNGARGTNAARTCNCAYTGGMGNTTYGCNGTN YTNYTNTGGGTNGTNGARGCNTTYATHAARYTNATHCARCARMGNTCNGAY--------- AAYGCNGAYACNAAYCCNAGYGGNGCNMGNCAYTCNTTYGTNGGNGTNGARYTNTAYTTY AAYTAYTTYGGNGCNGCNGTNGARYTNATGAGYTTYYTNYTNTGYGTNYTNGCNYTNYTN ACNATHMGNAGYYTNGTNYTNACNMGNGGNYTNAARYTNYTNAAYATGTTYYTNATHACN AARGCNATHYTNYTNTCNAAYYTNGGNTCNYTNYTNGCNATGCCNGCNYTNYTNTGGGGN AARTCNTGYAGYCCNTGGTTYYTNTGGYTNGGNCARGCNTTYGTNTGYYTNTCNTCNYTN CARGCNYTNMGNGTNGTNYTN---GTNGGNCCNCAYMGNACNYTNGTNGCNGCNGTNGCN GTNGCNTCNGGNTTYTGGTTYCARTCNGTNTCNTCNGAYGCNYTNAAYGGNTGGYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARMGNGGNAARTCNGAYTAYATGGGNTAYYTNYTNGTNGCNTGY AAYYTNGTNCCNAARTCNGARGARGAYAARGAYCARTTYTTYMGNMGNTCNGTNMGNTCN ACNGAYTCNGCNAARAARGTNAARATGCARCCNTGGAGYGGNATHGTNAAYGTNGTNYTN ATHGARGGNTCNCAYYTNGTNCCNATGGAYGAYAAYGGNYTNAGYGAYCCNTAYGTNAAR TTYAARYTNGGNCARGARAARTAYMGNAGYAARCAYAARTCNAARTCNYTNAAYCCNMGN TGGYTNGARCARTTYGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGCNTCNTCN AAYGTNTCNMGNACNYTNGTNAARTCNYTNAARGGNMGNTCNTTY---TCNGCNGCNGCN GCNCARGCNGAYMGNGCNCARACN---GAYAGYTCNCCNAARTGYTCNGTNAARAARYTN AGYAAYGGNGTNTCNGTNGGNGTNATHCCNTCNAAYTCNCCNGTNGCNMGNGTNGCNGTN GTNGCNAAYGCNGGNTCNMGNTTYGARAGYGGNGAYAAYYTNGGNATHTCNCAYTTYYTN MGNATGTCNACNMGNATHMGNACNGARAAYATGACNAGYYTNAAYGTNACNMGNACNATH CARCARYTNGGNGGNGAYATHACNATHATGGGNACNMGNGARTAYATHTAYTTYAARAGY AGYGTNACNMGNAAYTCNGCNGAYAARGCNATHAARATHYTNCARGARYTNACNACNAAR CARTCNTAYAARCCNTGGGARTTYACNAAYGTNCARAAYGAYCAYAAYGGNATGGCNYTN GAYYTNGCNYTNTAYGARACNMGNCAYGAYGTNMGNGCNATGGARYTNYTNCAYTCNGCN GCNTTYMGNAAYACNYTNGGNAAYTCNYTNTAYGCNCCNGARCAYATGATHGGNGCNTAY AGYCCNGARCARGTNATGCARTAYGTNAARACNTAYTTYAGYGGNGGNMGNYTNGCNYTN GTNGGNATHGGNGTNGAYGGNGGNYTNYTNGARGARYTNGCNTCNACNTTYGARCCNTAY GCNTCNTCNGGNGTNCCNGTNGARAARGCNTCNTAYTAYGGNGGNGGNGARAAYMGNGAR AAYACNGGNGGNGARGTNTCNTAYGTNGCNGTNGGNTTYGGNGGNCCNAGYYTNGCNAGY AARGAYYTNYTNGCNTCNGARGTNYTNMGNMGNATHGTNGGNACNGGNCCNCAYGTNAAR TAYAGYAGYGGNACNATHGGNGCNCAYATGGCNAARGCNGTNGCNGGNGCNGTNGAYGCN CCNTTYCAYGTNTCNGCNATGAAYGCNAAYTAYAGYGAYAAYGGNYTNTTYGGNTTYACN GCNGTNGCNCAYTCNTCNAAYATHGARAARGTNYTNCARACNGCNGGNAAYCARTTYAAR GGNYTNYTNTCNGGNAGYATHAARGAYCAYGAYGTNACNAARGGNAARAAYCARYTNAAR TCNGARATHTGYATGCARTTYGARAAYCCNGARGTNYTNYTNAAYTGGYTNGGNGARCAR GCNATGAGYAGYGAYCARGTNATHAGYCCNGARGAYATHTAYAARATGGTNGAYAAYATH TCNACNAAYGAYGTNAARACNGCNGCNAARGGNATHYTNAAYACNAARCCNTCNATGGCN GCNACNGGNAAYATHGCNAAYGTNCCNTAYYTNGAYAARYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TCNAAYATGMGNCAYCCNGGNGCNGTNGTNYTNACNTTYYTNYTN TGGTTYTAYCCNYTNATGACNYTNGAYMGNGTNYTNYTNGCNTCNGTNTTYACNTCNTAY ACNTTYTGGMGNCAYAGYYTNGARGAYTCNCAYTAYCARTAYGCNGARAARCAYTTYTCN TCNTCNCARTCNCARMGNAARTCNMGNTGYGCNGTNTCNTAYGARTAYGTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GAYMGNTCNTAYMGNMGNGCNMGN MGNGGNMGNGARACNTGYCAYTCNGCNCCNGGNACNYTNCARMGNCARCAYMGNAAYMGN CAYTCNGTNYTNGAYGAYCARGCN------------------------------------ ---CCNGCNCARCCNCCNCCNCCNCCNTAYAAYYTNTTYTCNGARGAYYTNTCNTTYGGN TCNGARTTYYTNCCNGGNGCNGAYATGCARACNAGYGTNCARTCNGAYTAYACNCCNGAR MGNAAYGGNAAYGGNGCNCARCCNYTNYTN------AGYCARGARCAYCCNTCNATHMGN ATHYTNTCNGTNGCNAGYGCNATHGAYGCNGTNAAYTCNCCNACNAARCCNACNAAYTAY ATHATHACNTCNTCNTCNCAYTCNCCNYTNAARTCNCARACNTAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARCCNTAYGCNTCNCCNACNCAYGCNGGNGGNYTNYTNGCNATGGAYAGYGCNTAY TTYTTYGARATGGGNGCNTAYGAYCCNGGNYTNAARATHTGGGGNGGNGARAAYTAYGAR YTNGCNTTYAARGTNTGGATGTGYGGNGGNAGYTCNGARTGGGTNCCNTGYTCNCAYGTN GGNCAYATHTAYMGNYTNMGNGGNGCNCCNTAYGGNGAYGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TGGCARACNAARTGYATGAARYTNGARAARGTNATHAARACN YTNTCNAAYCAYTGYGTNMGNGTNGTNGARCAYCAYGARGAYYTNYTNGTNAARTTYAAR ACNAAYCARGAYCARTAYGCNGCNYTNAARACNAARTGYAARGARMGNGGNGARCARATH AARCARGCNMGNGARGTNYTNATHCCNGTNTCNAAYGARYTNAARATGYTNMGNGARAAR TAYGARGTNGCNGTNMGNTGYCARGTNCARGCNGARTCNTTYGCNATHGARACNACNAGY CARAAYAARAARYTNAARMGNCARAGYCARAARATHATGGCNAAYYTNGGNACNGTNAAY GTNGTNGAYATHAAYATHGAYGAYGAYGTNGAYCARGAYGARGARGARAARAARTAYATH GARMGNYTNGGNCARCARATHGARGARYTNGARGARGARAARAGYACNYTNAARATHCAR GTNCARGARATGACNGARACNATHCARGAYGARAARGARACNAGYGGNMGNYTNAARGAR MGNATHGAYACNATGAARGARGARYTNCARCARGCNGARACNACNGTNAARGARCARACN GARYTNYTNCARAARGTNGCNGTNACNTCNGARATGGCNTAYAARGARTAYMGNGAYATG GARCARACNTAYMGNAARGARTAYACNGTNMGNAAYGARGCNGARMGNTTYGCNAARAAR YTNTGYACNGARMGNGAYCARGCNMGNMGNGARAGYTCNATGGCNYTNAGYCAYGTNGCN GAYAAYAARAARYTNATGGAYGCNATGYTNGARATHCARGARYTNAAYTCNAARTCNGTN CARATGMGNGARGAYTTYGAYAARCARACNCAYGAYYTNAARGARCARYTNAARGCNGCN AARGARGTNTAYAAYGCNGARAAYYTNGARGCNGARAAYGARGARYTNAGYGTNGARAAR GAYACNYTNCARGGNAARYTNGAYAARAGYGARACNGAYATGGCNGARYTNMGNACNAAR TAYGCNGAYYTNCARGARACNTAYAARGTNYTNGARACNAARTAYGARAARGCNACNGCN ATHCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNTCNGCNAARGTNGGNGGN TTYYTNTCNAARATHGTNGGNMGNAARGGNCARMGNGARMGNGCNAARGARCARYTNAAR AARGGNGGNGTNGCNYTNGAYGAYAAYCAYTCNAARGCNGTNGAYGARATGATGAARMGN ATHAARAGYGGNAAYGTNGGNYTNMGNCCNGTNYTNCARAARMGNACN---------CAR TCNYTNCCNGARAARGARGARCCNAGYGCNATGAAYGARYTNCARGGNYTNYTNAGYAAR ATGAARAARGCNMGNAGYGARGAYGAYYTNTCNGTNTTY---GGNGAYACNGGNGTNAGY GARAAYTCNGARYTNGGNAARATHYTNAARMGN---MGNCAR------------------ ---------CARYTNAGYCARGGNCCNCCNGARCARGARMGNAAY--------------- ------MGNCCNAARCCNGCNCCNMGNAARYTNTCNACNATHCARGAYGAYGCNGARGAY TGYTCNATHYTNMGNACNAAYTCNGAYTTYATGGCNATGGARGCNTTYGTNAAYAGYGTN AAYCAYYTNMGNGARMGNACNGGNGTNGAYTAYGGNTAYYTNGTNATHGAYGAYTGYTAY AGYCCNGTNMGNGCNTCNAARYTNYTNYTNGAYGTNYTNGGNMGNGAYATHCARGTNGTN GAYGARGTNACNGGNGARGTNYTNGAYCCNGAYACNATHTGGGTNGTNATHGGNGCNGTN TCNAGYCCNAGYACNATGGCNYTNYTNAGYTAYYTNAARGAYGTNCAYATHCCNGTNATH TCNTAYCARGCNACNACNCCNAGYYTNAGYAAYAGYYTNYTNTAYCCNTAYTTYTCNMGN ACNATHGCNAGYGAYACNYTNCARGCNGARGGNGTNGTNMGNATHYTNCARGGNATGAAR GTNACNCAYGTNGGNGCNYTNGTNGTNGAYAAYACNTAYGGNYTNGARYTNTTYMGNYTN TTYAARGARAARGCNGARACNAAYMGNATHTGYGTNGARGAYCCNTTYAARATGACNGCN GAYACNGGNACNCARGAYATHGARAGYGTNTTYGGNYTNYTNCAYGCNAARCARATHGCN GTNGTNGTNACNTTYGTNAGYTCNTCNCAYATHAARAAYGTNYTNGARGTNGGNAARGAY AARAAYTTYCAYTAYGTNGCNAGYGAYACNTGGATHCCNTCNMGNAARATGYTNGARGAY GGNMGNGGNAAYMGNGCNAARGGNTCNTTYGTNYTNGARCCNACNTCNCCNAAYTTYGAY TTYMGNYTNGARAAYCAYYTNMGNAGYYTNAAYTCNTTYAGYAAYAAYGCNACNGTNTGG YTNMGNGAYTTYTGGGAYGAYTAYTTYGGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYACNAGYGAYATHAGYTTYYTNGAYCCNATHAAYCCNAAY YTNATH---YTNGCNAAYCARGTNGAYAAYTCNYTNMGNATHAAYATHYTNCCNGGNGGN YTNTCNCARCCNATGTCNGTNGARGARAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AARATGAARMGN TCNGARMGNCAYATGATGMGNYTNAARAGYATHATHGCNAARGTNYTNACNGARAARGGN GTNGARMGNGAYAAYCCNATHTAYCARGCNTGYTCNAARAAYYTNYTNAAYGTNAGYATH GTNYTNYTNAARAGYYTNCCNAAYTCNMGNAAYYTNACNGAYGARATGAARTCNGTNGTN TAYGGNCARGTNCARCARATHATHAAYYTNGARAARMGNMGNTCNGGNATHGCNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TCNTTY ATHCCNTGGCCNMGNCAYAARAGYATHTAYGGNMGNAAYGGNCAYATHGAYGARAGYYTN ATGAGYAGYATHYTNGARGGNAGYGAYGARCAYGTNGTNGGNTGGTAYAGYTTYMGNCAY CARACNAGYCARATGCCNTCNATGAARGARTTYTCNATHCAYAGYAARYTNGCNCARCAY GGNGCNAARCCNGARGAYGCNGTNTTYTTYYTNTGYACNTCNYTNGCNAGYMGNAAYYTN TCNACNCAYTCNACNGAYCAYACNTTYATGGTNTAYMGNGAYGARMGNTTYATGAAYATH CARATGGARGTNAARAAYYTNGGNGAYACNTCNMGNATGGARTAYATHATHGARAAYTCN TCNCCNGCNACNTCNAARGTNATHAAYGCNACNATGGGNAAYTCNGGNAARAAYTTYATH GGNGCNTCNGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------MGNAARMGNAGYMGNAGYMGNGARAAR--------------- ---MGNMGNTCNMGNAGY---------------------MGNGAYMGNAARTCNMGNAGY MGNAGYAARGARMGNMGNMGN---MGNGARMGNGARAARGGNMGNMGNMGNAGYMGNAGY AARAGYMGNGARMGNAARMGNAAYAGYMGNAGYAARAGYGARMGNMGNMGNAAYAGYMGN AGYAARAGYMGNMGNGARMGNYTNCCNGARYTNACNGTNGARGARMGNGAYGTNMGNACN ATHTTYTGYATGCARYTNTCNGCNMGNATHMGNCCNMGNGAYYTNGARGARTTYTTYTCN TCNGTNGGNAARGTNMGNGAYGTNMGNYTNATHACNGAYAAYAARACNMGNMGNTCNAAR GGNATHGCNTAYGTNGARTTYGCNGAYCCNGARTCNGTNACNYTNGCNATGGGNYTNACN GGNCARAARYTNYTNGGNGTNCCNATHATGGTNCARCCNTCNCARGCNGARAARAAYMGN GCNCARCCNGCNACN---GCNGCNCCNACNCARAARCARGCNCCNGARGGNCCNYTNMGN YTNTAYGTNGGNTCNYTNCAYTTYAAYATHAAYGARGAYATGYTNMGNGGNATHTTYGAR CCNTTYGGNAARATHGTNGAYATHAARATHATGMGNGAYCAYGAYACNCARMGNTCNYTN GGNTTYGGNTTYATHAGYTTYGCNAAYGCNGAYGAYGCNAARAARGCNYTNGAYCARYTN AAYGGNTTYGARYTNGCNGGNMGNCCNATGAARGTNGGNCAYGTNACNGARMGNACNGGN GARCARGGNCARGGN------GCNCARAAYGGNGTNGGNGGNCARYTNGAYACNGAYGAR ATGGAYMGNGCNGGNATHGAYYTNGGNGCNACNGGNMGNYTNCARYTNATGGCNAARYTN GCNGARGGNACNGGNTTYCARATHCCNCARTAYGCNGCNAGYGCNYTNAAYAAYATGTCN ACNCCNGCNGCNGTNCCNGGN---------------GTNCARACNGCNGCNGCNGCNATH GCNGCNCCNACNGCNCCNATHGTNGCNAAYGCNATGGCNATHCCNCCNGCNGTNCCNACN ACNGTNGCNACNAAYGCNCCNCCNATHGCNACNCARTGYTTYATGYTNTCNAAYATGTTY GAYCCNACNTCNGARCCNMGNYTNACNTGGGAYCARGARGTNMGNGAYGAYGTNATHGAY GARTGYAAYAARCAYGGNGGNGTNYTNCAYATHTAYGTNGAYAARAAYTCNCCNTCNGGN AAYGTNTAYGTNAARTGYCCNAGYATHTCNGCNGCNGTNGCNTCNGTNAAYTCNYTNCAY GGNMGNTAYTTYGCNGGNMGNGTNATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AAYTTYATHGCNACNGAYGAYAAYATHCAY AARYTNCCNACNGAYCAYMGNGTNGTNCARYTNATGGAYTTYGTNAAYCAYACNGARMGN TAYACNATHTCNTTYTGYTCNAARCAYAAYYTNCARCCNYTNAAYTTYTTYTGYGARCCN TGYGTNMGNCCNGTNTGYMGNGAYTGYACNAARGCNGAYCAYAARGARACNGAYGGNCAY YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNTTYATHGAYTTYGAYTAY YTNGAYTCNYTNATHTCNACNAAYGCNAGYCARTAYGCNTCNACNATGTCNYTNGCNCAR TCNACNTCNAARTCNTCNACNGTNTCNAAYATHGGN---CCNGCNMGNAARCCNMGNATG CAYGCNMGNATHAGYAAR---CARCAYAARCCNTTYATHMGNACNTCNTCNCCNAAYAAR ACNCAYCCNCCNAAYTTYTCNCARGAY---AAYYTNATHGAYGTNGTNGCNGAYGCNCAR AAYAGYCCNMGNTAYAARGGNMGNGARACNAARMGNGGNAGYGCNGAYTCNYTNACNCCN GCNAARGAYYTNAARMGNCARAGYGAYGCNYTNACNCCNATHMGNGARATGACNAGYGAR GAYGARGAYGARGAYTTYGGNAARAARGTNTCNCARGTNTCNATGAGYCARATHMGNGAY AGYMGNAAYAARAARGARTTYGCNATGGARTCNCAYCCNATGGGNMGNGGNTGYGAYTTY ATHMGNACNGCNTTYAAYGTNGARGGNMGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNGARGARGARAARCARGTN CAYTCNGAYTTYTTYGAYGGNMGNCCNCCNAARACNCCNGARMGNTAYATHAARATHMGN AGYTAYATHATHGAYTGYTGGGTNAARAAYAARCCNATHTAYYTNAAYAARACNTCNGTN MGNCCNGGNYTNAARAAYTGYGGNGAYGTNAAYTGYATHGGNMGNATHCAYGCNTAYYTN GARTGYGTNGGNGCNATHAAYTTYGGNTGYGARCARGTNGCNTAYMGNAAYCCNCARMGN CAYGCNAAYGGNGGNCCNAAYAGYMGNGCNAARGGNATGAAYAARGARYTNATGGCNTCN TTYCCNGTNGTNAARTCNGARTTYATGMGNCCNMGNAARMGNMGNATHMGNGAYGARAGY GGNYTNTGGGTNGAYGARAARGARYTNGARGGNAARACNATHGAYCAYAAYGTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GCNGAYATHAGYGGNTCNATHACNGAYAGY GAYCARGAYGTNTGGAAYATHAAYMGNYTNGGNTCNATHYTNGAYCAYGTNACNAAYGAY TAYAAYATHAARATHGARGGNGTNTCNACNGCNTAYYTNTAYTTYGGNATGTGGAARACN ACNTTYGCNTGGCAYACNGARGAYATGGAYYTNTAYAGYATHAAYTAYYTNCAYTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GCNGAY ATGGTNGCNGGNYTNACNGTNGGNYTNACNGTNATHCCNCARGGNYTNGCNTAYGCNCAR ATHGCNGGNYTNCCNGCNCARTAYGGNYTNTAYTCNGCNTTYATGGGNTGYTTYATHTAY TGYYTNATGGGNACNTCNAARGAYATHACNYTNGGNCCNACNGCNATHATGTCNYTNATG ACNGCNACNTTYGGNGAYCCNAAY---CCNGARGTNGCNGTNACNTGYGCNATHGTNYTN ACNYTNGTNTCNGGNGTNGTNCARTTYACNATGGGNATHYTNAARYTNGGNATHYTNGTN AGYTAYATHTCNTAYCCNGTNATHAAYGCNTTYACNTCNGCNGCNGCNATHACNATHGCN TTYGGNCARATHAARAAYATHYTNGGNYTNACNGAYATHGAYMGN--------------- ---------------------------------ATGGCNGARACNGARYTNCARAARYTN YTNGAYATHCAYMGNTCNYTNGTNTAYGAYAARGARGCNCARAARATHAARTGYATHYTN ACNACNCAYGARATGCCNGCNMGNCCNAGYGCNATHGARAGYTAYGTNAGYGGNAARAAR TAYAARMGNGTNGARGAYCAYAARGARCAYATHGTNCAR--------------------- ---------AAYMGNAARAARGARAARGARYTNTTYTGYAAYYTNACNATGMGNCAYYTN GARAARACNCCNAARGCNATHCARMGNCAYATHTCNGGNMGNAARTAYAARAAYGCNYTN GCNMGNTGGAARGARTGYCARMGNGARGGNACNACNTTYACNCCN--------------- ---------------------------------------------AAYAAYTAYMGNAAR GCNAARAARAARGAYACNGARGAYGGNGAYGAY--------------------------- ---------AARGARGCNGGNGAYGARGAYAARGAYGAYGARGAYGAYCARGAYGAYGAR GARGAYGAY--------------------------------------------------- ------------------------------------------------------------ ---------CCNYTNCCNCCNGGNAGYATGGGNTTYCCNATHGTNGGNGARACNYTNCAR TTYYTNTGGAARGGNACNGARTAYTAYTCNGARAARTTYAARGARTAYGGNAAYGTNTTY AARTGYAAYGTNYTNGGNAGYCCNACNGTNMGNGTNTCNGGNGCNGARAAYATHMGNACN YTNATHGAYMGNGARCCNMGNCARYTNACNATGAARTGGCCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNYTNGCNGCNTTYMGNAAYYTNCAYMGNGCNMGNMGN GARGTNTTYGCNGGNGAYGARMGNGCNYTNAAYGARGTNMGNAAYCARATGAAYTCNGAR TTYMGNGARAARYTNCARGARACNGAYGAYTCNAARATHAARGARAAYTTYGTNYTNGCN AARGAYGTNGCNTAYYTNYTNMGNACNACNGTNGTNCARYTNCARCARAAR------GAY GCNGAYACNTTYGARATGMGNATHACNAARNNNACNCAYYTNCCNGAYAAYTCNCCNTTY GAYCCNACNAARGARATHCCNGCNMGNMGNMGNAARAARAARAAYTCNGGNTGYGCNGAY TCNACN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARYTNYTNCCNYTNYTNAARTCN---ACNGAYGCNTCN TTYTAYYTNCARCAYGCNGTNYTNAGYACNYTNMGNAAYYTNGCNATHCCNGCNCCNAAY AARCCNMGNYTNYTNGARCARGGNGTNATGGAYGCNTGYYTNTGYYTNAARAAYTCNGAR GTNATGGCNGTNATHTTYAARYTNYTNGGNYTNYTNMGNATGYTNATHGARGGNCARGCN TGYGCNGCNATHAARYTNGGNCARGARMGNGGNTTYYTNGAYTGYYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGACNAAYGTN CAYMGNATGTTYYTNCARAAYTTYATGTCNAAYGCNGTNATGAAYTAYACNGARGTNAAR GCNTGYTAYGCNCARTGYAARAAYMGNTTYTCNGARCCNTTYGAYGCNGARAAYATHAGY GCNCARATHGTNGCN---------------TTYGTNMGNACNATHAAYACNGCNATHTCN GCNTTYAAYYTNGARATHMGNAARGGNATHCARGARCAYGAYGGNTCNAGYGTNTAYTGY YTNGTNAAYACNGTNGARAGYGTNGTNTCNMGNYTNTCNACNACNTAYACNCARAAYGAR YTNGARYTNTTYAARAARYTNGTNGARCAYATHGTNGARTCNGAYGAYGGNAARATHGGN TCNMGNATHGCNYTNAAYYTNACNGARAARYTNGAYAARMGNATGGGNAARGARGARGCN CARAAYTTYYTNGAYAGYYTNGAYMGNGARAARTGGATHATHAARGAYGAYAAYGGNAAR ATHGCNYTNTCNGCNMGNACNYTNYTNGARYTNGAYCARTAYATHAARGAYATHTAYCCN GAYTTYGTNAARATHTGYAAYATHTGYAGYAARYTNGCNATGCARGGNGARYTNTGYYTN AAYTGYGGNGTNMGNATHCAYTTYAARTGYGCNAARACNTTYTTYCARACN--------- GAYAARAARTGYCCNAGY------TGYAARTCNGCNTGGAAYGAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNAARGARGARGTNAAYYTNATGGTNTGYYTNATHATGAARGTNTCNGTN GAYTCNTCNTTYCARAAYYTNGARYTNCARCAYACNTTYCARGAYYTNYTNTCNTCNYTN YTNGARTGYTAYAARGARTCNGAYTGGYTNTCNGTNGTNCCNTCNYTNTGYCAYGARYTN ACNACNATHCCNCAYCAYCAYMGNAGYTCNGTNTAYYTNGCNGAYYTNATGCCNYTNAGY GCNMGNGGNAAYTAYATHCARATHMGNTTYAGYTTYYTNYTNYTNTGYYTNACNYTNGAY CCNGAYMGNAARGAYGARCAYTCNYTNCARYTNGAYTCNATHMGNCCNTCNMGNATHTCN CAYYTNGGNMGNGARCCNCCNGARACNCARTCNACNTCNTGYYTNTAYTCNTGYYTNCAY GGNYTNATHAARGARGAYATHAAYCARYTNGAYTCNGCNATHACNYTNYTNGAYMGNGCN GTNGGNGAYGARACNAAYMGNATGGCNCARCCNAARGAYGARYTNGAYTTYYTNACNAAY CARGTNAARATGGTNATHAARGAYATHMGNGAYAGYATHAAYACNYTNGAYYTNTCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MGNAARGTNAARGTNTGGGGNMGNYTNMGNCCNACNTCNAAYTTYTCNCAYGAR AAYGTNGARGTNYTNCCNGAYAAYAARGGNATHAAYATHCAYATGMGNMGNGAYCCNAAR AARGGNGTNGTNAAYAAYCARATHYTNGAYTGGTCNTTYAARYTNGAYGGNATHTTYAAY AAYGCNGAYCARGAYGTNGTNTAYAAYACNGTNACNTCNGAYATHGTNTCNAGYTCNYTN GAYGGNTAYAAYGGNACNYTNATGTGYTAYGGNCARACNGGNGCNGGNAARACNTTYACN ATGACNGGNGCNACNGARAGYTAYMGNCAYMGNGGNYTNATHCCNMGNGCNATHTCNCAR YTNTTYMGNCARATHGARGAYMGNYTNGARTAYAGYATHACNGTNMGNGCNTCNTAYATG GARATHTAYAAYGARCARATGTTYGAYYTNYTNGGNACNTTYCCNGARGCNTCNTGG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNTCNTCNTCNTTYGARTGGACNATHACNAAY TAYTTYGARAARYTNGARYTNGARMGNTGGGGNAARAAYCCNAGYYTNCAYTCNGARCCN TTYTAYACNGARCARTCNGGNTAYMGNGCNAGYYTNGARYTNTAYYTNAAYGGNAAYGGN TCNGGNCAYGAYAARMGNATGTCNGTNTTYYTNAGYATHATHAARAGYCAYCAYGAYGAR CAYYTNCARTGGCCNGTNACNTTYTTYYTNTCNTTYATHYTNYTNAAYCARGARGARAAY AAYGTNGAYTCNYTNATGCAYGARGCN------------ACNTTYCARTAYAAYAARCCN TCNGGNGAYTCNCAYGAYAARAGYGAYACNTGGGGNGTNATHGARTTYGTNCCNCAYTCN GTNATGAARNNNMGNAARTAYATHAARGAYGAYGCNATHACNYTNAARATHMGNATGATG GAYTTYGAYTCNTCNGCNAARTTYATHTCNTCNYTNGCNAARTTYYTNCARTCNYTNTGY AAYGGNTAYGTNGARTTYGAYAAYGGNGTNGARGTNATHGGNCAYATHTAYYTNAAYGTN GAYACNGGNAARAARATHGAYTAYGTNYTNAAYGARAARGTNTGYAARACNGAYGARAAY AGYGTNACNTTYATHAGYAAYAGYTTYCAYGCNCARCCNGCNGARAARCCNAARCCNGTN GAR---------CCNAARCCNAARGCNCCNACNCCNATHGARCARGARAAYGAYGARATH ATHGTNATGGAYGAYTCNGAYCARAAYTAYAAYGAYCARCARTAYAGYAAYGAYAAYGTN CARYTNCCNTCNACNCARCARCCNMGNCCNCCNCAYGCNTCNAARMGNTCNTAYAGYCAR TCNTTYTCNTCNTCNAAYMGNCCNYTNAARTCNTCNAARTTYAAYTCNTCNTCNTCNAAY CCNAAYGGNGCNCAYYTNCCNTCN------GCNAAYGAYAGYTCNTTYAAYGTNGCNGGN AAYATHACNGCNGCNACNGARTCNGAYYTNTCNCAYYTNTCNCARGTNTTYCCNGARAGY ATHGAYCCNTCNGAYCCNCARAGYGAYATHAARCCNATHYTNGAYAARGAYYTNCAYGTN ATHGGNGTNAARCARGARTAYGAYCCNTCNGCNCAYCARGGNGARGGNAGYACNTAYGAY GAYCCNGGNGAYACNAGYTAYTAYTCNMGNAAR------TTYCCNATGTAYATHGTNGAY GCNTTYACNAARAARGCNYTNAGYGGNAAYCARGCNGCNATHTGYYTNGTNCCNTCNGAY GTNACNYTNCARGARGAYGARATGGTNAARATHGGNGCNGARATGAAYYTNTCNGARACN GCNTAY------ATHYTNGAYAARGARAGYGAYTTYGARTCNGGNAGYAARTTYTCNYTN MGNTGGTTYACNCCNACNAAYGARGTNAAYYTNTGYGGNCAYGCNACNYTNGCNTCNGCN GCNGTNYTNATHGAYGGNGTNGGNAAYTCNAAYAARGTNATHCARTTYTCNACNAARAGY GGNACNYTNTCNGTNAGYMGNCAYCCNGAYAARACNGGNTTYYTNACNATGGAYTTYCCN AARAAYGARCCNAARCCNCARGAYACNGAYATHYTNGARAARYTNYTNYTNAGYYTNGTN GGNGAYMGNGAYATGATHCARGARGTNCARTAYTCN---GCNACNACNAARAARYTNGTN GTNMGNTTYAARGAYCAYATHCAYMGNAARGARYTNGARMGNYTNAGYCCNAARCCNAGY ATHYTNATGGARGCNGARCCNTCNGGNYTNGTNATGGGNGTNGGNGTNACNYTNAARGGN TGYCAYGCNAAYGGNTGYGCNGAYGAYGARGGNAAYGTNTAYGAYTTYGTNTCNMGNTAY TGGGCNCCNTGGAAYGGNATHCCNGARGAYCCNGTNACNGGNTCNTGGCAYACNGTNATH GGNCCNTAYTGGGCNAARGARYTNGAYAARACNATGYTNTAYGCNMGNCARTGYTCNCCN MGNGGNGGNGAYATHYTNGTNGARGTNAARGAYACNMGNGTNACNYTNATGGGNCARTCN GTNATHAAYYTNAARGGNACNTTYCARYTNATGGGNAGYAAYCCNAARAARCARTCNAAR TCNTTYAARGTNYTNCARTGGATGACNGARACNGARAARGAYGARGGNAARGCNGARGAR AARGTNAARGARTCNACNCCNACNAGYGCNGGNCCNMGNMGNCAYMGNGAYCCNGAYYTN MGNCAYAAYGCNGAYGAYGAYGARATGMGNTTYACNGGNYTNCAYGCNAARTCNGARATH CCNTCNAARACNTTYGAYMGNYTNAARAARACNCCNGARGARAAYGGNGAYGAYATHCCN CARAAYGAYGARGAYGAYACNGAY------------------GARGTNGGNAAYTAYAAY GARGCNTCNATHMGNTAYACNGGNAARAGYATHCCNTCNCCNGCNTTYMGNGTNYTNCAR ACNTGGGCNGARCAYGAYCCNGAY---------AARGGNGGNCAYGARGGNCAYYTNCCN AARYTNYTNGARAARTGYYTNAARAARTTYCARCCNGARAGYAARTAYGCNGAYGAYCCN MGNTTYATHAARATGTGGATHGARTAYTCNAAYTTYATHGAYTCNCCNGCNGARGTNTTY TCNTAYATGTTYGAYAAYGGNATHGGNACNAARGTNTCNCARYTNTAYATHGARTGGGCN ATHAARYTNGARATGGCNGGNAAYATGAARAARGCNGAYAGYATHTAYACNGARGGNATH AAYMGNATGGCNGARCCNMGNGAYYTNYTNATGCARAARCARGARCARTTYCARCAYMGN YTNGCNAARAAYATHACNYTNCARGTNGCNGAYCCNACNAARCCNGARGCNATGGARGAR CCNGARGARAARMGNCARGCNYTNACNMGNYTNAARCCNGCNGGNGGNGGNCAYAARGTN GGNACNAGYMGNACNGGNGCNGTNACNGCNGGNTCNGCNGGNMGNYTNAARGAYGGNMGN CCNGTNGCNCCNAARCARGTNCARTCNCARMGNTTYGCNGTNTTYAAYGAYGARAAYGCN GCNCCNCARYTNATGCARACNAAYGARTGGGTNTCNATGCCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGCARTGYCARAGYYTNMGNGARCARYTNCARGCNAARGCNGGN MGNGAYCCNGTNGGNYTNCCNGCNGARCCNAAYTCNAGYGTNGAYTTYGARTCNCAYTCN GAYAAYGCNAGYGAYGAYCCNGTNYTNGARATHAGYATHTCNTGYTCNAAYYTNCCNTGY GAYAGYTCNGAYGCNYTNCCNAAYCCNYTNGTNGTNGTNCAYACNATGYTNCCNCCNCAR CARCARATHTGGYTNCAYCAYAAYCAYACNGARATHGTNGARMGNTCNAGYAGYCCNYTN TTYYTNAARACNATHGGNTTYGGNGAYMGNTAYGGNGTNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARACNAARYTNTGYACNAAYTGYAARMGNGAYATHGCN GCNAAYAAYTTYGTNATGCAYGARATGCAYTGYMGNMGNCAYATHGTNYTNTGYGAYCAR TGYGAYGARCCNATHCCNMGNTCNGARYTNGARCARCAYTTYAAYGAYATGCAYCARAAR GTNCCNTGYGARYTNTGYAARACNGARATHGARAARGAYAARATGGARGAYCAYATGGAR AAYATHTGYYTNAARAARCARATGACNTGYGARTTYTGYGARYTNTCNTAYGCNAARGAY GGNATGGARGCNCAYGTNGAYTAYTGY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNAARTCNGARCAYGTNAARGTNGARGAR GTNGCNMGNGCNAARTGGATHTGYYTNAAYAARATHACNTAYAARGAYCCNCAYGGNAAR GARMGNATHTGGGARGGNGTNTCNMGNACNACNAARAAYGTNGGNGARGCNGAYGCNGTN GGNATGATGTCNGTNTTYCAYGAYCCNATHACNGAYYTNCARAGYGTNATHYTNATHMGN CARTAYMGNCCNCCNATGGARACNTAYACNATHGARTTYCCNGCNGGNYTNATHGAYAAR GGNGARACNGCNGCNACNGCNGCNATHMGNGARATGAARGARGARACNGGNTAYGAYGTN ACNGTNGTNGAYGTNTCNCCNGGNACNTCNYTNGAYCCNGGNGTNGGNAGYACNACNYTN AARATHGCNACNTGYAARGTNGAYATGAGYAARGAYAAR---GARGARMGNCCNAARCCN ACNGGNGGNGAYTCNGAYGARTTYGTNCARGTNGTNGTNCARCCNATGAAYACNYTNATG GARAARYTNAARGARTTYTCNGAYCARGGNGAYTGYGTNGAYTCNMGNGTNTAYTGYTGG GCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GTNGARGARAARATG GAYGARGARGARGTNGTNGARAARGARGTNGARAAYGGNGGNGGNGARGAYTCNGARGAY GAYTTYGAYYTNGAYGAYYTNGAYAAYATHGAYMGNGTNYTNGARAARGCNYTNGARAAR AARMGNGAYCARAARAARTCNGGNGAYCARACNTCNCAYGTNCCNTCNACNACNCCNTCN YTNGCNGCNGCNGCNGCNGARACNATHAARACNGARACNGAYMGNGARGCNGTNGARTCN TCNTCNGTNGAYGGNTCNGCNATGAGYGARACNGAYATGAARMGNYTNAARTAYGCNGTN AARGAYTCNGCNGARYTNGCNYTNCAYAARYTNCARTTYYTNGAYATHTCNACNAARAAY YTNTCNAARYTNCARGTNYTNYTNGTNGARYTNCARACNMGNTAYAAYGAYTGGCARTCN GGNGGNYTNTCNACNCARTAYTTYCAYAAYCARYTNAARTCNTCNGARGCNYTNYTNTCN CARTAYGARGARAGYGCNGTNCCNCCNGGNTGGTCNTGYCARTGGGAYMGNTAYGAYCAR TCNCCNTTYTAYYTNCAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARCARATHGTNCARGAYACNGCNGTNACNTGY ATGGAYMGNGGNAARGTNTCNTCNTTYGTNCARCAYMGNGGNTCNGTNCCNYTNTTYTGG TCNCARGAYATHTCNAARATGGTNCCNAARCCNCCNATHTCNYTNGAYCARMGNGAYCCN TAYTGYAGYGCNGCNGGNATGCAYTTYAAYGARATGYTNTCNMGNTAYGGNTCNCCNATH ATHGTNTTYAAYYTNGTNAARACNMGNGARAARAARMGNCAYGARTGYATHYTNAGYGAR GAYTAYATHCAYACNATHGARTAYYTNAAYCARTTYYTNCCNGCNGARCAYAARATGAAR TAYATHGGNTTYGAYATGGCNMGNGTNAAYAARMGNAARGAYGCNGAYGTNATGYTNMGN YTNAAYMGNATHGCNMGNTCNTGYYTNAARCARACNGGNTTYTTYYTNMGNGTNCARCCN CCNCARGCNCARTAYYTNATGAARGAYAGYGARYTNGARAGYYTNAARGGNYTNTGGGGN CCNAAYGGNATGMGNCARACNGGNGCNGTNMGNACNAAYTGYGTNGAYTGYYTNGAYMGN ACNAAYACNGCNCARTTYGCNATGGGNMGNAGYGCNYTNGCNTAYCARYTNTAYGCNATG GGNYTNATGGARMGNCCNCARYTNGARTTYGAYACNGAYTGYGTNAARYTNYTNGARGAR YTNTAYGARGAYCAYGGNGAYACNYTNGCNYTNCARTAYGGNGGNAGYCARYTNGTNCAY MGNATHAARACNTAYMGNAARATHTCNCCNTGGACNTCNCAYAGYMGNGAYATHATGCAR ACNYTNTCNMGNTAYTAYAGYAAYGCNTTYTCNGAYYTNGARAARCARCARGCNTTYAAY YTNTTYYTNGGNGTNTAYATHCCNCARGTNGGNGARCCNAAYYTNTGGGAYYTNCCNACN GAYTAYTAYYTNCAYAAYAARGCNTGYYTNGGNAARCCNATGCCNMGNCARAAYTAYTGY CARTGGTGGGAYGCNGAYGTNTGGGARACNYTNCCNYTNCCNMGNGAYGARGTNAAYAAR CCNAARGTNGTNCAYCCNGCNATGYTNACNACNAGYCARMGNGAYGARCAYGTNAAYTCN TTYTAYGARCAYTAYMGNCCNGARGARYTNTCNGTNTTYGAYGARATGTAYCARATGTAY YTNTCNCARGCNTGYTGGAARCAYYTNCCNAARCAYGCNAAYGAYTTYAGYCCNTTYTGY GTNMGNCAYGTNGTNGCNGARATHGARTCNAAYCCNAGYATHTCNGCNAARGAYTCNACN TCNTCNACNACNTCNTTYGGNTCNGARGGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CARGARTCNYTNMGNAARYTNCARCARGCNCARAARGAR CARYTNGCNAAYATGCARYTNCCNGCNGCNAGYAAYTGGGCNAARCAYGCNTCN---CAR GGNAGYGTNGGNCAYTCNAARTCNYTNACNGARATHCARGARGARGARGCNMGNMGNGAR AARGARMGNCARAARGARCARCAYGCNATGAARCARMGNATGCARGARCARGCNGCNATH YTNCARCARCARCARCARCARAARTCNTGGGCNTCNCARGTNTCNMGNGGNATGTCNMGN GGNCCNTCNYTNYTNGAYATHCARCARCARGARAARGARAAYGCNAARAARGCNGARAAR GARMGNGGNAARGCNAAYCAYCARGCNAARTCNGGNYTNGGNAGYGGNAGYGCNMGNCCN ACNAGYGCNGCNACNAAYTCNACNTGGAGYGTNATGACNCCNTCNCCNGTNGCNGCNCCN GTNAGYACNGGNGGNATHTGGGAYATGGGNGTNCCNCARTCNGTNAARAARCCNCARCAR GGNAARAAYGGN------------YTNGCNGCNTCNTCNATHCCNGGNYTNCARCAYCAR CARCARCARTCNAARAARAARGCNGCNGARACNAAYAARGCNGCNGCNCCNGCNAARCAR AARCARGTNGARTCNGTNCARAARYTNTTYCAYAAYAARAARCARGAYGGNTTYTCNTCN TGGGTNACNGARAARYTNTCNMGNTTYTCNTCNGTNATHGAYATHCCNACNTTYGTNTCN TTYATHGTNGARGTNGAYAGYCCNCAYGAYGTNYTNGAYTAYGTNAARACNTAYYTNGGN GAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------MGNGAR TAYAAYCARYTNYTNCARCARAARGCNAAYCCNMGNGGNMGNCARMGNGARGAYGARATH GAYAAYCCNTCNATHATHCCNTTYAAYMGNGCNGARCARGARMGNGTNAARGCNAARATH YTNGARGARGARMGNCAYMGNGARTAYAAYGAYAGYYTNGCNAARCARGTNCARGAYMGN TCNAARMGNGARGTNACNCCNGTNCCNAAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARCCNACNYTNACNGARYTNMGNGARGARMGNACNTCNYTN GARAARGARYTNYTNATGACNGAYAAYYTNACNTAYACNCCNCAYGTNGAYAARCCNYTN TTYAAYAAYTTYMGNAARCCNYTNYTNGCNAAYCCNYTNAGYGCNACNGCNGCNGCNMGN ACNTCNMGNCARAGYCCNGTNAARGCNAAYCAYTTYATH--------------------- ------GCNAAYGARGARTAYGTNGARGARAAYTAYCARAARGCNATHGAYYTNTAYACN GARGCNYTNGTNGTNGARGAYACNMGNGAYGAYATHTAYTGYTTYMGNGCNCARGCNAAR YTNTCNYTNGGNAAYATGTCNGAYGCNATHAARGAYTAYGAYGARGCNYTNMGNYTNAAY ATGAAYAAYCARAARGCNTAYATHAARAARGGNTCNGTNYTNYTNAARATGGGNGARGTN YTNCARGCNCARAGYGTNTTYATHGARGGNCARAARCAYTGY---GGNGARAARGAYTTY GARGAYTGGYTNGARAARTGYMGNATGAARGARYTNGGNATHAGYCARTCNACNGARACN TCNAAYGTNCCNCARYTNGTN------------------------ACNTCNATHAARCAY AAYTGGTAYCARACNCAYACNCAYGTNATHGTNACNGTNATGGTNAARAAYGTNAARAAR GARGARYTNACNYTNGAYGTNGARGAYMGNTCNYTNMGNATHAGYATHAAYMGN---GGN GGNGARTCNAGYGAYYTNAAYATGACNYTNGCNCAYCCNGTNGTNCCNGAYCARACNCAR TCNAARYTNTTYTCNACNAARATHGARATHAARYTNAARAARTTYGARGGNATHCARTGG GCNAARYTNGARGGNTCNCCNGAYAARGCNGAYACNAGYGTNYTNCCNGTNTGYGCNGCN CCNGTNAAYACNAGYGARGCNCCNMGNTAYCCNAGYTCNTCNCAYTTYTCNMGNGAYTGG GAYAARYTNGCNGCNGARGTNACNGARGARGARAARAAYGARAARYTNGARGGNGAYGCN GCNYTNAAYCARTTYTTYCARAARATHTAYGCNGAYGCNACNGAYGARACNAARAARGCN ATGATGAARTCNTTYTCNGARTCNGGNGGNACNGTNYTNAGYACNAAYTGGGAYGARGTN GGNAGYAARAARGTNGAYGTNAARCCNCCNGAYGGNATGGARTAYAARAARTGGGAR--- ------ATGCCNAARMGNAARTCNGARGARGCNCCN------------------------ ------AARAARGTNGARGARCCNGCNAARAARGCNAAR------GCNGARCCNGTNCCN ---GARAARMGNGGNMGNGGNMGNCCNCCNYTNTCNGCNGARGARAARGCNAARMGNGTN GAR---AARAARCARCCNTCNGGNMGNGGNMGNGGNMGNCCNAARGGNTCNACNAARGCN TCNAARAARGGNAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNGARAAYGAYTTYGTNAAYGTNGTNGARTTY TCNGARACNGCNAARTTYGTNAGYAARTGYTTYAAYCAYACNGCNTTYGTNCARGCNAAY TTYMGNAAYAARAARCARYTNGARAARGAYGTNGAYAARGTNGARGCNYTNGGNCARGCN GAYTTYAGYGTNGCNATHAARTTYGARAARTTYMGNGARTTYGCNMGNAAYGARACNAAY GAYGARAAYAAYATH--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYGARGAYMGNACNAAR YTNGAYGAYYTNATGGCNGCNAGYACNACNATHMGNTGYGGNTCNMGNCARCCNACNTCN ATHGAYGAYGAYGTNAARACNAARGCNGARAARAARAARGCNATGTCNYTNTCNYTNYTN MGNCCNGAYYTNGTNCARAAYGAYCCNAARAARGAYGAYMGNGAYACNGCNTTYGCNCAR AARTAYTTYAAYMGNGTNAARGARACNYTNTCNTCNGAYCCNGARMGNTTYTAYAARTTY YTNTCNYTNYTNAARGAYYTNAAYAARGAYCAYACNAGYCCNGTNGARYTNTAYYTNGAY GTNGTNTCNYTNYTNTCNGAYCAYCARCARYTNGTNGARGAYTTYGCNGGNTTYYTNYTN TCNTTYCARGCNGTNGARTGYCARTGYTTYTCNACNAAYTTYCARTAYTCNCARATHMGN CARTTYYTNMGNCARGTNGARGTNCAYTGYGGNTCNTCN---ACNGCNACNTAYMGNAAR GTNYTNAARGCNYTNTCNACNTGGAGYATHATGTGYCARGARGGNAARYTNGARGGNGGN YTNMGNGTNAARATGYTNGGNATHYTNAARAAYGTNCCNGGNGTNYTNGAYAAYYTNATH AGYTAYTTYYTNGAYGGNGCNGTNTCNGARTGYCAYAARATGGAYTTYGARGAYGTNTGY YTNGAYGARGARGAYGAYCARATGATHGARGGNGAYGGNTTYGARAAYGTNGTNYTNCCN GAYGARCCNGARGAYTAYAAYACNAARACNTGYACNTGYGARTGYCAYAGYAGYAAYACN CARGAYGARMGNTAYCARMGNMGNATGAARCAYTGYATHTCNTGYAGYYTNCARGTNTAY GARGGNCARCCNGTNYTNAARATGTCNMGNTAYGARTTYMGNCCNGTNTCNATHGTNTAY CCN---------TCNGARGARGARGAYAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARYTNGTNGCNGTNATHAARACNTAYCCNTGGCARTGY ATGGARTGYAARACNTGYGTNCARTGYATGGAYCCNTAYGAYGARGAYAARATGATGTTY TGYGAYMGNTGYGAYMGNGGNTAYCAYACNTTYTGYATHGGNYTNGAYGCNYTNCCNACN GGNCAYTGGGARTGYMGNAGYTGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNMGNTTYATHTCNGCNGAYGARGTNAARGARGGNTCNTGGATG TCNAARACNAARGTNYTNTGYGTNGGNGGNGGNTAYGAYYTNGGNTAYATHGARTCNYTN GGNTCNTCNGGNATGMGNAAYATHMGNGARTTYGTNAAYGGNGGNGGNGGNTAYYTNGGN ATHTGYGCNGGNGCNTAYTTYGCNTGYGAYTTYATHGARTTYGAYAARAAYGGNCCNYTN GARGTNGTNGGNGARMGNAGYYTNAARTTYTTYCARGGNAARTGYATHGGNCCNGCNTTY GCNGGNTTYGAYTAYAAYTCNMGNAARGGNGTNCAYGCNGTNCCNGTNYTNTAYCAYAAY YTNGARGTNCARGCNTAYGCNGARGGNGGNGGNTAYTTYATGCCNTAYGAYCAYTCNTCN TCNTCNTCNCARTCNCARGAYYTNGGNMGNTAYACNACNYTNGAYGAYTCNCCNGCNGCN ATHGTNAARTCNCARTAYGGNCARGGNTCNGTNGTNYTNTCNGGNGTNCAYATHGARTAY CCNGTNAARTGYYTNGAYTGYAARGAYAARTAYATHTCNAARATGYTNCCNCAYTTYTTY ------------------------------------------------------------ ------ATGGCNAARMGNGGNCCNCARTCNGARYTNACNGAYMGNAAYTGGGAYGAYGAR GARGARGTNGARGARGCNGGNGTNTTYACNCARGCNACNGCNGAYGCNATGCARACNMGN GTNATHAARAARGCNAARMGNMGNGGNGGNGGNGARGARAARGGNGCNTTYGGNGGNTTY GGNGGNTTYGGNGGNYTN---------GCNTCNAARGCNGCNGCNYTNCCNAARCCNTCN CARATGTTYGGNATGGGNGGNCCNTTYGGNTTYAARCCNTTYTCNGGNGCNGCNGCNACN TCNTTYATHGAYYTNGCNGCNGCNAGYAGYAARAGYGCNTCNTCNACNAARGAYAAYACN TCNTAYYTNCAYTCNYTNAARGCNYTNAAYGARAGYGTNYTNGCNTGGATHAARCARCAY GTNGAYAARAAYCCNTTYATHATHYTNACNCCNATHTTYAARGAYTAYGARAARTAYGTN GCNAGYYTNGARGCNAARAARACNACNACNGTNGCNGCNAAYGGNTCNGGNTCNGCNTTY TCNCCNTCNTCNTCNYTNGGNGCNTTYGCNCARAARAARTCNACNACNTGYGAYTCNGAY YTNGAYAARGAYGGNAARAARGAYGGNGAYAARGAYACNGARTCNACNCCNAARGCNTCN ACN---------TTYACNTTYGGN---ACNGCNTCNGCNGCNAAYGGNGAYGGNTTYAAR TTYTCNACNGCNACNGCNACNACNTCNAAYTCNGGNTTYAGYTTY---------GGNAAR ACNGCNACNTCNCCNGGNTTYTCNTTYGGNCARAGYAGYTCNTCNTCNTCNTCNACNACN GCNGCNGCNGCNACNGGNTTYTCNTTYGGNAGYAGY------------GGNACNACNACN ACNTCNGCNCCNTTYGGNGCNTCNGGNTTYTCNTTYGGNTCNYTNGCNACNGCNAARGCN GCNTCNGAYAARGCNCARGCNGGNAAY---TCNCARGGNGGNGGNGAYGAYGAYGARTAY GTNCCNCCNAARCCNGARGTNAARGARATHAARGARGARGGNTCNYTNTTYTCNAARMGN TGYAARYTNTTYCAYCARAARGAYGGNAGYTGGGTNGARMGNGGNGTNGGNAAYGTNCAY GTNAARCCNYTNGAYGARCCNAARACNCARYTNYTNATHMGNGCNGAYACNAAYYTNGGN AAYATHYTNYTNAAYATHAAYGTNACNTCNGCNYTNCCNACNTCNMGNCARGGNAARAAY AAYGTNYTNYTNGTNTGYGTNCCNAAYCCNCCNYTN------------AARGARGGNTCN ACNGAYCARACNCCNATHCCNATGYTNATHMGNGTNAARACNGCNCARGARGCNGAYGAR YTNYTNGCNAARYTNGARGARMGNAARGCNYTNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CAYCCNMGNGGNGTNMGNCCNGARGCNCARTCNAAYGCNTAYAGYAAY AARGGNGGNAAYATGAARAAYYTNATGGARAAYTAYGGNAAYYTNACNGTNTCNCCNAAR MGNGARCCNAARGTNAARGGNAGYGARGCNCARGARTAYAARGARMGNGARCARGGNAGY ACNAARGTNYTNYTNGAYCAYTAYAGYMGNGAYCCNYTNCCNGARAGYACNATGCCNCCN CCNCCNMGNYTNGGNCAYGGNGCNGARGARATHGCNATHAARCAYAARGGNGARCARATG GGNCCNYTNATGMGNYTNGARGGNAARAARACNCCNMGNTCNCCNAARCARGGNCCNYTN CAYCARACNTCNACNGGNGCNGGNTGGGAYGARAAYCCNCCNCAYAAYMGNTGYMGNCCN GARGGNGARAGYATHGCNCARAARAAYAGYGCNGAYTCNATGGGNGCNATHYTNYTNCAR AAYAAYGTNCCNCCNCCNCARAARAARGARGGNAARGTNYTNAARCAYYTNCARCARTCN GAYATGTCNAGYAARGTNCCNCCNCAYMGNGTNMGNGAYGAYGGNYTNCARAAYTTYGAR AARGCNCAYAAYMGNGARGARATGACNGCNATHATGMGNGGNAGYCCNAAYGTNAGYGAR GTNMGNCCNMGNAGYGGNAARAARGTNATGCCNCAYYTNCARAARTCNGARYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNATGAARCARATHGCNTTYMGNACNGTNGGN YTNYTNTCNACNGTNMGNGTNTGGTCNATGYTNCARCCNMGNGTNGARGTNMGNAAYYTN CAYGAYGCNACNGTNGCNACNGCNMGNAGYTTYACNGARATHATHATHTCNCCNCAYCAR GCNGARGTNYTNAARMGNGARGAYMGNTTYYTNTAYATHTGGGGNACNGCNGGNACNGGN AARACNYTNYTNYTNTCNYTNAARGGNMGNGCNTGGYTNMGNAARAAYMGNACNGTNATH ATHYTNAAYACNMGNTCNTAYTGGGTNTGGGGNCAYTCNTAYACNTGYGAYTGGACNGTN GTNTGGACNGCNAARGGNGCNGTNATHACNTCNTGGGCNGTNGGNTGYATHATGTTYGTN ATHTTYYTNGCNTTYGAYCCNYTNGGNGCNYTNGARGAYMGNAARTCNGTNMGNYTNMGN GTNGGNGGNGAYGGNGARGARCAYGTNATGATHGGNAGYACNTCNGCNAAYAARGTNTGG GARACNMGNTGYMGNYTNATGTGYTGYTGYATH--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MGN GCNGTNAARMGNACNGAYAARGTNGCNTCNCCNTTYACNCCNATGGCNCCNTAYGAYGAY ATGAAYACNCCNGAYYTNAARAARGCNGTNGGNAARGTNGGNGTNMGNCCNATGGGNAAR AARMGNATGMGNGAYYTNYTNAARCAYATHTAYAARGARACNCAYCARTAYGARACNGAY TCNGAYGAYGGNATHACNCCNGTNAARMGN------------------------------ ---------------CCNAAYCCNAAYGCNCCNMGNAARGARGCNYTNGARTTYACNGAY YTNGCNAAR------------------------MGNCARYTNYTNYTNTCNACNAARTCN CCNGARAARGGNATHCCNCAR------------GGNTCNGGNAGYGGNAGYGGNCAYMGN YTNGARAARGGNTTYCCNAAR--------------------------------------- ------------------------CCNTCNACNTCNTCNTCNGTNACNGAYTTYAAYGAY ---GARCARGGNGGNGGNGARGAYGAYATHYTNAGYTCNCARGAYTCNAGYTTYAGYGAY GGNCCNGAYTTYCCNGARGARAGYATGYTNCARGTNYTNCCNGARGARGARGAYGTNGAY GCNCCNTGYACNCARYTNACNCARACNAGYATGGARGTNYTNAAYAAYMGNYTNATGGAY TTYYTNAARGAYAAYCCNAARATHTAYGARCARATHYTNATGTAYGARGCNYTNGARYTN GAYGTNYTNAARAARCARATHTCNGAYGCNGGNATHMGNGTNGGNTAYCCNAARYTNCAR GAYTTYYTNGAYGARMGNTGYATHACNTTYTCNATGAARAAYATGAGYAAYMGNAAYAAY MGNCARMGNCAR------------------------------------------------ ------------------AGYGTNTCNGCNATGGGNGTNAARYTNGAYGGNTTYYTNGAY GTNYTNAARGARAAYGTNYTNGAYGARYTNAARGCNTCNYTNATGTCNGCNYTNMGNGCN CARCAYGGNGAYCAYATGAAYTCNYTNGARGGNYTNCARGCNGAYAARYTNGCNTTYCAR AARGARGTNAAYAARYTNAAYGARAARYTNAAYAGYYTNGARYTNAAYGTNCARCARAAR TGYACNGTNATHAARAAYYTNACNGAYTCNYTNGTNGCNCARAARAARAARGTNGARATG GCNAARCAYTTYTTYCAYTGGAARGCNGAYCAYCAYGAYAARCARMGNGARATHTTYACN GARAARYTNGCNACNCARCAYCAYGARMGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG GGNMGNAARAARATHCARATHGCNMGNATHAAYGAYGARMGNAAYMGNCARGTNACNTTY ACNAARMGNAARTTYGGNYTNATGAARAARGCNTAYGARYTNAGYGTNYTNTGYGAYTGY GARATHGCNYTNATHATHTTYACNAGYAAYAAYAARYTNTAYCARTAYGCNAGYTCNGAY ATGGAYAARGTNYTNYTNAARTAYACNGARTAYAAYGAYTCNGTNGTNAGYCARACNAAY AARGAYATHATGGAYATGYTNAGYAARAARGARAGYAARGGNGGNGAYTAYGAYGGNGAY GAYGAYGAYTTYCCNYTNTCNCCNMGNACNGAYGARAGYTAYMGNAARATHGAYGCNGAR TTYGCNMGNGCNATGAAYGAYGGNGGNYTNAARTCN---ACNGTNCARTAYCARATHCCN GTNCARACNCCNGCNGCNCARTAYACNGCNGCNCCNGCNAGYATGGCNAGYGGNGGNTCN GTNATHGTNYTNCARCCNTCNGGNGCNATHGGNAAYCCNGTNAGYMGNCCNCARGGNACN CARATHAGYACNTCNTCNGGNYTNACNGCNCARAARATHACNYTNAAYACNAAYGTNTCN AGYGGNGGNGCNCARGCNCAYCCNGTNGCNYTNCAYATGGCNGGNGARATHCCNMGNGTN ATHGCNACNTCNTCNACNTCNTCNAGYCCNCARTCNACNGCNACN------AARAARCCN GGNYTNAARGTNGTNATHCCNGAYMGNGGNCCNGCNGTNACNCARGTNCAYAARATHCAR GGNACNGCNYTNGAYACNCCNAGYGTNTCNATHGCNACNCCNAAY---AGYCARAAYGCN CARGGNGCNATHCARGCNATHYTNCARTCNGGNGAYYTNYTNAAYAGYGCNGAYATHGCN GGNYTNTCNCCNYTNGTNTAYCARYTNACNAAYCARGGNTCNGGNCCNGGNCCNYTNACN GCNGCNYTNCARGCNTCNGGNGTNTTYACNCCNGGNGGNTCNYTNTCNATGTCNACNACN CCNATH---------ATHACNYTNCCNCCNCARAARTCNGARYTNGTNAARCARGARCCN CCNGGNTCNCCNAGYMGNCAYGAYCAY------------TCNTCNATHACNCCNCCNCCN GCNTCNAAYCARGGNGARCCNCCNGARAARMGNCARMGNTAYGAYACNGAY--------- ------------------------------------------------------------ ------------------------GAYGGNGGNGGNCCN------------MGNGGNGGN TTYTCNGGNCARAARTGYTAYAARTGYAAYMGNACNGGNCAYTTYGCNMGNGARTGYACN CARGAYCARGARMGNTGYTAYAARTGYAAYGGNYTNGGNCAYATHGCNAARGAYTGYGAR AARCARATHTCN---ACNGGNGCNTGYTAYAAYTGYGGNAGYAGYGARCAYYTNCARMGN GAYTGYCCNGARGCNATHGTNAARTCNTGYTAYMGNTGYGGNGARTCNGGNCAYYTNGCN AARGARTGYCCNGCNGAYATHCCNGGNAARCCNTTYGCN------------GAYGAYMGN AARTGYTAYACNTGYGGNGGNGTNGGNCAYYTNGCNAARGAYTGYCCN------------ TCNCCNMGNAARGARTGYTAYMGNTGYAAYCARACNGGNCAYYTNCARAARGAYTGYCCN AAYGGN---CCNCARAAYGCNCARTGYTAYAAYTGYAAYGARGTNGGNCAYATHGCNMGN GAYTGYACNGCNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TCNACNGCNTCNCCNCCN YTNCCNCCNCCNCCNTCNTCNGARATHCCNGAYCARTTYGAYTAYCCNGCNCCNCCNCCN CCNCCNGAYTTYAGYGAYGARMGNGARGGNCCNCCNAGYATGMGNGAYGGNGTNGCNCAR CCNYTNGARAAYGAYATHTAYGGNACNGCNATGGGNYTNGGNGAYGAYCCNTAYGCNGCN ACNGGNCCNCARTTYYTNGCNCARACNTCNTGGGTNCCNAARCAYTAYYTNGARAARGTN ATHGCNATHTAYGAYTAYCARGCNAAYAARGGNGAYGARYTNTCNTTYGCNGARAAYGCN ATHGTNTAYGTNATHCAYAARAAYGAYGAYGGNTGGTGGGARGGNGTNATGGAYGGNAAR ACNGGNYTNTTYCCNTAYAAYTAYGTNGARCCNTGYATG--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CCNGCNGTNGCNCCNATHTTYTCNTCNGCNYTNCARGCN CAYAARATHTGYGCNACNMGNYTNCCNGTNGARYTNTCNYTNGARTGYAARGGNTGGATH AARCCNGCNGTNGTNCCNTTYTAYAARCARGTNATGGCNGAYGCNGARAARTGYAARTCN AAYTTYAAYACNTGYGGNGTNMGNTAYACNGAYGCNTTYGTNGGNYTNTCNACNATGGGN GCNGAYATGACNGARGCNMGNYTNCARTCNAGYATHYTNAARGGNTTYCARGAYGCNGAR AARCARCAYATHGARTCNCCNMGNTCNTTYGTNACNTGYGARGTNATGTGYCAYCCNGGN TAYGCNACNGGNAARGAYGCNGGNGGNTTYGAYGGNCAYTCNGAYGARTTYGGNTGYTCN MGNGAYMGNGARCAYGARATHMGNGTNYTNAGYTCNAARGARATGCARGARTTYTAYGAR AARAAYAAYATHCAYYTNGTNTCNCAYGARTTYYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNCAYCARCARGTNGAYGAYYTNMGN GARMGNYTNTGGAAYGTNTGYGAYGAYMGNAARGARYTNGCNGARMGNGARMGNGARACN AAYATGAAYGAYGGNTGGYTNGARGAYMGNYTNGGNATHYTNAGYAAYCAYTAYYTNACN YTNATGCARTCNGARGTNGAYMGNYTNCARGAYACNGTNMGNATGYTNAARGAYTAYTAY MGNGGNATGGAYGGNCARGTNCCNGAYGARYTNAAYCCNGAYTAYGAYMGNATHCCNYTN ATHGARYTNCCNGTNGARMGNCCNGARACNCCNGARGGNGCNMGNAGYGARACNGCNCAR TCNCCNGTNGAYGAYGCNMGNTCNGARMGNGGNTCNTCNACNCAYTCNAARTCNCCNMGN GGNGGNMGNMGNTCNAARTCNCCNAARGAYMGNGCNAARTCNCCNAARGGNTCNMGNTCN TCNMGNACNGCNTCNGGNAARAARAARAGYAARGGNGGNAARGARACNCCNGTNCCNGAY GGNCCNAARTCNTCNGARGGNATHGGNMGNMGNATHGTNATHCCNYTNGTNCCNMGNMGN CCNGCNTCNCCNGAYAAYGAYGTNAARGTNGGNGCNACNCCNAGYAARGARAARMGNGAY AARAARTCNYTNAARAARGGNGTNTCNGCNGTNGAYGAYYTNCCNAGYGCNGARAGYCCN GCNCCNCCNCARGAYATGGAYGARAARYTNATHTAYGAYGGNTAYAGYTTYGCNGTNAAY GGNYTNACNCARATGATHCARTTYGARATGCARGCNMGNGARGCNGARGARGARGCNGAR MGNYTNMGNGARCARGARMGNGARMGNGARAARGARAARGCNAARGGNGCNAARGCNGCN AARGGNGGNAARAARGGNAARAGYMGNAGYCCNTCNCCNAARAARGGNGGNAARGGNAAR GARTCNGARACNTCNGCNACNCCNCCNCCNGTNCCNTCNGARATHAGYGARGARGAYGTN CARAARAARTCNTCNAARGARMGNGCNMGNGARGARTAYTAYTTYTCNATHCARGARGAR GARCARGCNTCNAARATHMGNYTNGAYYTNATHMGNATHYTNGCNTGYGCNATHYTNCAR GAYYTNAARTCNAARGGNGARGARGCNTTYAARGAYATGAAYGAYTGGYTNGGNTCNMGN TAYYTNAARGARATGGARAGYATHGAYCARATGTCNGARGTNGTNMGNAAYGCNATHGAR GTNAARGARAARYTNGCNAARGARGTNYTNYTNGARCARGAYAAYTTYATHGTNGAYGAR GAYYTNAARGTNYTNMGNACNCCNAGYCCNCCNATHCCNCCNCCNCCNGTNGARCARCCN ACNCCNGARCAYTTYACNGTNAAYCARYTNACNTCNYTNTAYGARCARTTYMGNGCNTCN GCNCCNACNGGNATHATHTCNAAYAARGCNTTYGTNGARATGTTYGARAAYATHGTNTCN GTNACNCAYGGNATGGARGCNYTNCCNGAYGTNTGGACNCAYYTNTCNCCNTCNCARATH CARGAYYTNGCNTCNATGYTNTCNTCNGARACNGAYTAYGTNGAYTGGMGNMGNYTNYTN GTNGCNYTNAGYCAYCCNGTNCCNACNCCNACNCARCARCARYTNYTNGAYACNYTNGCN MGNTTYAARAAYATGGAYCARAARAAYACNGGNACNGTNACNMGNGARCARTGGCARMGN ATHGCNYTNTGGTTYGAYGCNGARCCNGCNTCNGAYCAYGCNTAYAAYMGNYTNGCNCAY YTNCAYMGNGCNYTNTTYGARATGTTYGCNGAYCAYACNGGNTCNATHTCNCAYYTNCAY TAYAAYAGYTTYAGYATGTAYTTYTCNGCNGTNGCNAAYTAYCAYGARGGNTTYYTNMGN GCNYTNAGYATHGCNACNTGYCARCAYATGCCNMGNYTNGGNAARCCNTCNYTNGCNTCN CARACNACNCAYYTNGGNGARMGNGCNACNAGYGCNGTNGAYAGYTTYATHCARGARGCN GCNGARTAYAARGAYGAYGARAARCCNCAYTCNGARCCNCCNATGTCNGAYGARGTNATH CCNCCNGARGCNAAYGARGCNGTNGTNTCNGTNGARGCNYTNTTYCARGTNYTNCAYCAY GGNGARATHTCNAARGGNGAYAGYCAYMGNTTYAGYGTNACNGCNGAYCCNGARGARCAR ACNTCNTTYGARMGNYTNAGYGCNGTNTTYCARGARYTNAAYGARGAYGAYAGYACNTCN CCNATHTCNTAYAARATHYTNATHGAYCAYCCNYTNATHCARGAYGTNGTNGTNGCNTGY AARCAYTTYAARGCNYTNGAYATHAARAGYYTNATGGCNTCNACNTCNAAYGAYGTNGCN GARATHACNAGYYTNAARACNATGGAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNYTNMGNCCNATHGCN---TTYGGNYTNTAYGCNAARACNGGNAARTCNGTNCAYACN ACNTCNAARAARTAYGCNCARGCNYTNTAYMGNGARCARATGTAYGAYTTY------AAR GARCCNAARTAYATHCAYAAYGCNGGNACNGCNTTYAGYGCNTTYYTNTGGTAYTGGATH YTNTAYCAYTGYTAYTTYGARTGGGARCAYYTNGTNACNAARAAYTGGGCNTCNYTNCAR ATGACNAARAGY---------------------------------TTYYTNAAYAARYTN GGNGARATHCCNGTNYTNAGYGAYGGNTGGTTYGCNGCNGCNGAYTAYTAYTCNAARGTN MGNGAYTAYAAYGCNYTNATGMGNATGACNTTYTCNGTNGCNGARTCNGGNGTNAARGTN GCNGGNCARYTNTCNTCNCCNGTNYTNAAYCAYTAYCARCCNCARATHAAYAAYYTNAAY GAYATHGCNTGYAARACNYTNGAYAAYYTNGARACNAARTAYCCNGCNATHAARCARCCN ACNGARCARTGGAARGARACNTGYGCNGAYTAYGTNGARCCNGTNATGGGNMGNGTNAAR CCNGTNATHTCNCARGTNCARGGNATHGTNGAYAGYGGNAARCARMGNATHAAYGGNATH AARACNGCNAGYACNAAYATGATGGARGGNGCNAARAAYMGNGGNGTNGGNACNGTNACN CAYGTNGTNAAYACNACNTTYGGNACNGTNCCNGGNMGNTTYGTNACNMGNACNGTNGAY AGYGCNYTNGAYATGGCNGAYAAYYTNGTNGAYMGNTAYYTNCCNGAR------GARAAR GARCARGAR---------------------------------GARGAYATGAARGAYGAR GARTCNGARGCNGARTAYGARAARATGGTNGARATGGAYCCNACNCCNAARMGNGTNYTN GTNCAYGCNGGNTCNGTNACNGAYAARATHMGNAARMGNATGTAYMGNMGNGCNATGAAR GAYYTNACNTAYGCNMGNGCNMGNACNGCNACNGCNYTNAARAARATGACNAAYACNGTN GARYTNATGGAYATGGCNAARGARAAYGCNAAYGCNGCNAARGARAARGCNAAYCAYYTN TGGACNGARATHGTNAARGAYACNGAYGTNTCNGAYGARAAR------------AGYYTN TTYGTNGGNACNGTNGARGAYMGNATHGTNGCNYTNGGNMGNGTNATGGCNMGNCARGTN MGNTCNGGNGTNACNGCNTTYGARAARGCNTAYTCNGARYTNGGNGARTTYAGYAARAAY CCNATHTCNAARTCNAARGARTAYAARGARYTNATHGCNACNTTYYTNACNGTNGAYTCN ATHAARAAYATGACNTCNCARAAYYTNCARMGNGCNMGNGARTCNYTNAARTAYYTNCAR GAYMGNYTNAARAAYATHGTNAAYYTNACNCCNGCNYTNAAYTGGATGGCNGTNGAYATH AAYATGGARGAYATHCCNATHAAYGARGCNGAYATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNATGTGGTAYMGNATGGCNACNACNCARGAR ACNTAYMGNYTNTCNGAYCARYTNATHMGNGCNATHGGNAARGGNAARCCNCAYGAYMGN GARGAYGAYATHAAYYTNYTNATHGAYAARGGNGCNGAYATHAAYMGNMGNCAYGGNTCN YTNYTNCCNYTNCARTAYGCNTGYTGYYTNMGNGAYTGGCAYGTNYTNCARATHYTNATH CARMGNGGNGCNAARGTNAAYGARCCNGAYGGNTAYAAYMGNACNGCNYTNCAYTAYGCN TCNGARCARGAYCARAAYTGYGTNMGNATHYTNYTNGARAAYGGNGCNYTNGCNGAYCAR GGNGAYGGNAAYGGNGAYACNGCNYTNCAYTGGGCNGCNTAYAARAAYAAYACNYTNTGY GTNCAYMGNYTNYTNGARCAYGGNGCNAAYGTNAAYGCNGCNGAYTTYAAYAAYGAYACN CCNGTNAGYTGGGCNGCNMGNAARGGNAAYYTNGAYGTNATHCARGTNYTNYTNAAYTAY AAYGCNGAYGTNGAYATHMGNAAYATHCAYGGNCARACNGCNYTNAARAARTCNGCNGCN YTNCARGCNAGYGGNYTNAAYAAYGARGARGAYGAYGCNTGYYTNGARYTNYTNATHAAR GCNTCNGGNCARTTYGAYYTNACNAAYYTNAARGGNGARYTNYTNCCNGTNATGGCNMGN GAYAAYMGNYTNAAYGARATHYTNMGNCCNYTNGTNACNAARCCNMGNCCNYTNYTNGAR CARTGYMGNAARMGNATHMGNCAYGCNATHGGNCARGCNTAYYTNCCNGAYGCNATHCCN MGNYTNCCNGTNCCNMGNAARYTNCAYGARTTYYTNYTNYTNAARAARACNGCNTTYGTN ACNGGNGGNGCNCARGGNYTNGGNCAYGCNTAYGTNCARAARTTYYTNGARGARGGNGCN AAYGTNTTYTTYGGNGAYGTNAAYGCNGARGTNGGNACNCCNGCNGARCARAARYTNCAR GARAARTAYGGNAARGAYMGNGTNATGTTYTCNGCNTTYGAYGTNACNAAYGGNGARAAR TTYAARGARGCNTTYGAYAARGCNGTNTCNCAYTTYGGNAAYATHGAYGTNTTYGTNAAY AAYGCNGGNATHYTNAAYGARGCNGTNTGGGARAARATGATHGARATHAAYTAYACNGGN ACNGTNMGNGGNACNAAYYTNGCNATGGARCAYATGMGNAARGAYAARGGNGGNAARGGN GGNMGNATHATHAAYATHAGYTCNGTNATHGGNYTNACNGAYCAYCCNTCNGCNTCNGTN TAYTGYGGNACNAARCAYGCNGTNMGNTCNTAYTCNACNAGYATGTCNATGATHCCNGGN YTNGARTCNGCNYTNGGNATHGARATHGGNATHATHTGYCCNGAYCCNACNAAYACNGCN YTNATGACNGARYTNGAYGAYGAYAARYTNCAYGGNTTYGCN---------------ATH AARGAYAARYTNCAYGAYATHATGATHTCNGTNTCNYTNGTNGTNGAYGGNYTNTTYTCN YTNYTNAARMGNGARGAYAGYATHAAYGGNGCNATHYTNYTNGTNAARAARACNGGNGCN ACNTTYCARAARATGGARAARGTNGAYYTNGGNAGYGARTGGCCNATHCCN------GGN AARGTNTGYTCNGARAAYTCNCARTGYCARCCNGGNGARTGYTGYCARATHATGAGYGAR TTYAARATHGTNAGYAARMGNAARGTN---------------GCNATHAAYGGNATHATG CCNATHAARGGNACNTGYGARCCNTAYAARYTNGARGGNGAYTCNTGYGGNACNTTYGCN MGNGCNAAYGGNTAYTGYAGYTGYGARCCNGGNACNMGNTGYMGNAAYTTYGARGTNTCN ACNGAY---AGYCCNMGNYTNTCNMGNMGNAARATGGCNGCNGCNMGNCCNGGNTAYCAR TGGATHAGYAARTGYACNAAR--------------------------------------- ---------------------GTNTAYGAYTTYGGNTGYCAYYTNYTNGCNCCNCARCAY TCNYTNGTNYTNTTYCCNTCNACNGTNCAYTTYYTNGAYYTNAARYTNTCNGTNATGAAY AARGCNGGNYTNACNATHGGNYTNGAYGTNTAYYTNCARTAYTTYYTNMGNCCNAGYGAR YTNTCNYTNATGTAYMGNMGNTAYAAYMGNGARTAYGARTCNGTNGTNMGNMGNATGGCN GARAGYACNGTNAARAAYATGGCNATGGAYTTYAGYYTNGARGARTAYAARATGGARMGN CCNATGGTNGARGCNAARYTNTTYACNAARYTNMGNMGNGTNYTNTCNGGNGAYTGYTGY TGGCAYAARMGNCCNCARAGYAAYAAYACNAAYACNAAYACNAGYTTY---------GAR TGYAAYACNACNACNTCNTGYGAYCARGGNTAYCAYGTNGAYYTNGCNTAYTTYCARATG GGNGCNATHAAYATHCCNGAYAARATHATGCARTTYTAYYTNAARMGNATHATHYTNGAR GARGARACNAARMGNGARYTNTTYATHCARAARAARGCNATHGTNGTNAARCAYACNAGY YTNYTNGTNCARAAYATHTCNAAYCARGCNAAYGARATHATHCARGARGCNMGNGCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ACNGCNTCNYTNGCNGTNATGGCNYTNGTNYTNCCNGGNGTNTCNGCNYTNAGYGAYMGN ATHCCNGTNATHGCNTCNGCNGCNGTNGCNYTNTTYATGYTNYTNATHYTNATHGTNGCN ATHGTNTTYGCNTCNTGYTAYGCNCAYACNTGGATHMGNAGYAAYATGAARMGNAAYGGN AARGTNAARATGCCNMGNTCNTAYTTYGARAARAARAARGARGCNAARMGNMGNYTNGTN GCNGARTCNGTNMGNTCNTCNMGNYTNACNCARGAYACNTAYGTNCCNCCNGCNCCNATG GTNAAYGGNGGNCCNGCNATGGAYAARGARACNYTNGTNCARGGNTGGCARCARGAYACN MGN---------MGNGTNTAYGARGARAARGGNTAYACNYTNGARATGGGNGAYGARAAY GARGARGARTTYCARATHGARACNACNYTNGTNGAYAAYGARGTNYTNGAYGTNGGNCCN TAYAARAAYYTNTCNTCN---ACNAAYGCNAARCCNGTNGAYGGNAAYGTNTAYTCNAAY CCNTAYATHTAYTCNAAYAAYGAYMGNGTN------------------------------ ---ATGGCNTCNTAYYTNCARAARGARGAYGCNYTNMGNYTNGTNTCNAGYGTNGAYAAY TTYYTNTTYGAYTGYGAYGGNGTNYTNTGGGARMGNGAYCARCCNATHGCNGGNAGYYTN GAYACNATHYTNAARYTNAARGARATGGGNAARMGNATHTAYTAYGTNACNAAYAAYAGY TCNAARACNMGNGCNGAYTAYYTNAARAARTGYCARGAYYTNGGNTTYCCNGCNGARGAR GAYGAYATHYTNTGYACNGCNTAYATGGCNGCNCARTAYYTNAARATGCARCARTTYAAR GGNAARGTNTAYYTNGTNGGNAARGAYGARAGYYTNGGNAARGARYTNAAYGAYGCNGGN ATHMGNTAYACNGGNACNGGNCCNGAYCCNATHTCNATH---GARCARGCNGAYTAYYTN AAYACNAARYTNGAYCCNGARGTNAAYTGYGTNYTNGTNGGNTTYGAYCCNTAYATHAGY TAYTCNAARGTNYTNAARGCNAGYAGYTAYYTNAARAAYCCNGAYTGYYTNTTYGTNGGN ACNAAYGARGAYCCNTGYYTNCCNACNAAYGGNCCNATHAARYTNCCNGGNACNGGNACN ATGGTNGCNTTYGTNAARGCNGGNGCNGARMGNGARCCNGTNATHGTNGGNAARCCNGAR GTNGGNATGTTYGAYATHYTNCARAARYTNCAYAAYYTNGAYCCNTCNMGNTGYYTNATG ACNGGNGAYMGNYTNGARTCNGAYATHGTNTTYGCNAARAARTGYGGNYTNAARTCNTTY YTNGTNYTNACNGGNAAYGAYTGYAARGARGAYATGGARAARMGNGGNATH------ACN CCNGAYTTYTAYGGNGAYTGYYTNGGNACNYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNGARGAYTAYGAYCCNGCNGARCCNACNGAR GAYGAYGAY------GAYGGNAARGAYAARGAY---TCNAAYYTNTAYTGYCAYGTNTGY TCNGTNTCNGTNTAYGAYGARGARAGYTTYCARMGNCAYYTNAAYGGNYTNAARCAYAAR GCNMGNATGGARAGYATHGCNTCNGTNCAYAAYGTNMGNTCNTCNCARATGAAYTTYMGN YTNAARGCNGARGARCAYYTNMGNAAYATHGARMGNAARGGNGGNMGNGAYCCNGAYTAY TTYTGYAARATHTGYAAYAAYGAYYTNGCNATHCCNTGGGARAARCAYMGNTAYTCNAAY ATHCAYAARCARMGNYTNYTNCARGTNMGNAARGGNTGYGGNTGGTGYAARGTNCAYGAY TTYACNAAYTTYACNGARGTNYTNGARCAYMGNGARACNGAYGARCAYAARAARAAYGCN GAYYTNTAYGGNAARAARGARGAYGARAARGAYGAYTCNMGNCARMGNATHAARGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TAYGAYCCNGTNACNAARGAYYTN AARAARGTNTGGATGTGYAARATGCCNGTNCAYGGNGCNYTNYTNAGYTAYMGNGARCAY YTNYTNTCNYTNGGNGAYAARATHAAYAARATGGGNGTNGAYMGNGTNGARACNGCNYTN YTNTGYGCNATHAGYATGACNAGYATHGAYTGYCCNGGNYTNGTNAARCCNGCNACNGTN TCNGARGTNCARAGYGTNYTNATHGAR--------------------------------- ---------------------------------------------AARATHGGNGGNCAR CCNGTNTGGATGACNAAYTCNAARTCNACNGCNGTNCARAARTGYCCNGGNTGYTCNGTN GCNYTNACNYTNGTNGTNCARYTNTAYTGYCCNYTNTCNAAYTCNGCNTAYCAYMGNTGY YTNTAYATHYTNGTNTGYACNTCNACNGGNTGYCCNCARCAYAAYAGYTGGAARGTNTAY MGNGGNATGCARTAYGAYGARACNTAYGCNCCNGCNAARTCNAARAARGARGCNTCNCCN GAYAAYGARATGTGGACNGAYGAYCARGAYGAYTGGGGNGAYGGNGAYGAYGAYTGGGGN ACNTGYMGNYTNGAYCARYTNGCNTCNGTNYTNAAYACNAARTAYAARGAYTCNCARCCN TCNTCNMGN---------------MGNCCNGTNYTNYTNAARCCNTAYTAYYTNTCNGTN GTNGARGGNAGYGGNCAYATHTCNCAYAAYGCNACNGARGAYGGNCAYATHGCNAGYYTN ATHMGNAAYTAYGARGARGTNGARGGNAARAARATGAARGAYATHATHAGYGARMGNGCN CARACNAARGTNAARGGNGGNTCNGARGTNTAYGARAARTCNAAYGTNAARCAYGGNGAY AARGTNTTYCAYAARTTYTGGAARGARATHCARAARTTYCCNGARCARTGYATHMGNTAY GAYMGNTGYGGNCARCCNYTNYTNGTNCARAGYYTNAGYCCNATHCARTCNATHGTNCCN CCNTGYACNAARTGYGGNTCNAGYMGNGTNTTYGARTTYCARYTNGTNCCNGCNYTNATH CCNTGGYTNTGYTCNCARGARGGNAARCAYTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATHCCNCCNAARGTNCARGARMGNTAYYTNTCNGTNGTN AARGARTTYATHGARCARGGNTTYYTNGAYTTYATHCAYGGNYTNAARYTNGCNGTNATG AARGARTTYGGNAGYATHTCNYTNAARGARCARYTNGGNYTNGAYAAYYTNGCNTCNATH TTYGGNCAYGTNMGNGARMGNGTNGARTGYGGNGTNGAYAARCCNACNATHTCNYTNTAY CCNTAYYTNATHMGNTGYGARCARGTNGCNGTNCCNGAYGCNCARAAYGTNGTNAGYCCN GAYGAYGARYTNTAYGAYAARYTNATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARGAYCCNGAYGGNAAYGAYTCN TTYTTYMGNAGYTGYAGYTGYMGNATGAAYMGNYTNTCNCARCARGCNCARTCNYTNYTN MGNYTNCARATHTCNCARYTNTTYTTYAAYGCNGARAAYCCNGAYATHCCNGAYYTNGCN ATHACNTTYYTNATGGCNCARTAYATHCARGTNGTNGARGAYGARAAYGAYGARACNATH GARATHCCNAGYGARYTNAAYGGNACNYTNYTNYTNACNACNYTNTCNGCNCARTTYCCN GGNGCNTGYGGNYTNAARTAYMGNAAYCCNGARACNMGNGCNTTYMGNGGNATHMGNYTN GTNGAYGGNGTNYTNCAYCCNGARAAYGGNTCNTGGGGNAAYCAYYTNTAYGTNGCNGTN TTYCCNAARGARAAYAARMGNAARGGNGARGAYGGNTTYGAYAAYCCNGCNGCNAARACN AARMGNYTNGAYAGYCARAARTGYTCNGAYYTNATHGTNYTNGGNYTNCCNTGGAARAGY AAYGARGAYGAYYTNAARAARCAYTTYAGYCARTTYGGNGAYYTNGTNYTNGTNCARGTN AARMGNGAYATGAARTCNGGNCARTCNAARGGNTTYGGNTTYATHMGNTTYTCNAGYTAY GARGCNCARGTNAARTGYTGYGCNCARMGNCAYAAYATHGAYGGNMGNTGGTGYGAYGTN ACNATHCCNAAYTCNAAR------------GTNGGNAAYCARGGNTAYGAYTTYTCNCAR TAYGCNCARGGN------GGNTCNAGYMGNAAYTAYAAYTAYAAYCARGAYGARGGNMGN TAYCARGARGGNAAYAAYCCNATGATGAGYMGNAARGTNTTYATHGGNMGNGTNAGYGAR GAYYTNACNGTNGAYGAYYTNMGNGCNTAYTTYTCNAARTAYGGNGARGTNGTNGAYGTN TTYATHCCNAARCCNCAYMGNGCNTTYGCNTTYGTNACNTTYGCNGAYGCNGAYAGYGCN CARGGNYTNTGYGGNGARGAYCAYATHGTNAARGGNACNAGYGTNCAYGTNAGYAAYGCN GCNCCNAARACNTCNTAYGARMGNGGNGCNGAYMGNAARGGNTTYGGNGGNCAYATHGGN CARGGNGGNGGNTAYATGCARCCNTTYGGNGCNMGNGGNCCNGGNCCNGTNGGNGGNAAR ACNAAYGGNGCNGAYGGNAGYATGGCNGCNAAYAAYATHGGNATGAAYYTNATHAAYTCN GCNATGYTNGCNGCNGCNCARGCNATGYTNGCNAAYCCNAAYAGYTGGAGYGGNATGAAY CARGGNACNCARGGNGGNACNGGNGGNAGYATGGGNGGNGGNGAYCAYCCNTCNTCNATG GGNCARGTNTCNAGYCARGGNGGNTTYGGNAGYATGGCNGCNGGNACNGGNGGNAAYACN GGNACNGGNGCNTGGTGGGGNAAYGARGGNAGYTCNTCNTCNGGNGGNCAYTAYAGYGGN TGGGGNGGNTCNCAYGGNGGNMGNGGN---GCNAAYTGGAGYATGGCNGCNGGNGGNATG AGYYTNGAYAAYCCNGCNTTYMGNTCNTTYATHGGNTAYGCNGCNGTNGTNYTNYTNAAR ACNGTNYTNATGAGYGGNGTNACNGCNTTYTAYGGNATHACNAARAARGTNTTYGCNTCN GAYGARGAYGTNTCNTAYTTYAARGARAAYAAR------AARGGNATGGTNYTN---AAY GAYCCNGAYGTNGARMGNGTNMGNMGNGCNCAYMGNAAYGAYYTNGARAAYATHYTNCCN TTYGTNYTNYTNGGNGCNATHTAYTGYACNACNGGNCCNGTNYTNTCNACNGCNYTNYTN CAYTTYMGNATHTTYACNGCNGCNMGNATHYTNCAYACNGTNGTNTAYYTNYTNAARATH CCNCARCCNGCNMGNGTNATHGCNTTYTCNGTNGGNYTNGGNGTNAAYYTNTCNYTNGTN TAYMGNATHYTNATGCARGCNGCNTTYGGNATHTTYCARCCNCAYATHCARCAYYTNYTN TGYYTNGCNACNTCNGTNGAYATHGTNYTNYTNGGNGTNAGYTTYTCNAARACNATGGAY GGNGAYGAYMGNGARATGCAYYTNYTNCCNGAYCCNYTNTTYTCNATHCCNACNGAYGGN ATHTAYTTYACNTCNATHGTNGGNTGYAAYAAYGGNMGNGTNTTYATGGCNYTNGTNTAY CARGCNAARGAYGGNTGGTTYAGYGARAARTGYTAYAARGTNAAYCAYTCNACNAGYTCN TTYTCNTTYYTNGTNCCNTCNTTYYTNAAYTTYTCNTTYGGNGARGAYGAYGCNYTNGTN CARATHTGYATHGAYGAYTCNMGNGGNATHYTNTAYGGNMGNACNCARAAYGGNTCNATH CARGTNTTYGAYYTNGGNGARAGYAARAARGGNYTNAGYAARGTNGCNTAYCARTCNCAR GCNTCNATHYTNAAYTCNGCNTCNGCNATHGCNMGNACNATHGARAARTCNAAYTTYAAR TCNATHATGCAYATHTCNGCNATHACNCAYMGNGARGCNGARAGYGTNCAYYTNGTNGCN ATHACNGARACNGGNGTNMGNYTNTAYTTYTCNACNGTNCCNTCNAARCARYTNGAYTAY MGNCCNTGYACNYTNAGYYTNATHCAYGTNMGNYTNCCNCCNGGNTTYTCNGCNACNTCN ACNCCNGARMGNCCNACNAGYGTNCAYACNGCNTTYTAYAARAARGAYACNYTNATGYTN GTNTCNTCNCARAGYCARGAYMGNGAYATHYTNTGGTGYATHAGYCCNGAYTCNTTYCCN TTYCARAARCARYTNATGGARGCNCAYACNATHATHTCNTGYGGNGGNAARACNTGGGCN ATHGARGARGTNAAYCCNCARTCNTCNCCNATGMGNCAYATHACN--------------- ---------GAYCCNCCNTGYGTNGTNAGYCARCAYGCNTAYCCNCCNMGNMGNTTYGTN GTNYTNAGYACNCAYGGNGTNCAYATHGTNCARAARYTNMGNCCNGTNGARCARYTNMGN GTNYTNYTNYTNGARTGYGGNGGNCCNGAYTCNGARCARGTNAARGCNTTYTTYMGNYTN CAYAARYTNGAYCARGCNTGYGCNATHTGYYTNGTNYTNGCNTGYTCNMGNGCNGCNGCN GAYCARCARGTNTCNGAYTGGGCNMGNATGGCNTTYTTYATGTAYGGNGGNGARGCNCAR TGYAAYTTYGCNAGYATGMGNCCN------------------GGNAGYCCNYTNCCNAAY ATGTAYAGYCCNGGN------ATGYTNCCNAAYAGYCCNYTNCCNAGYATGYTNACNTCN ACNCCNGCNCCNGGNGCNATGGTN---------------GGNGGNAAYCCNAAYGCNYTN CARCARGARGTNATHTAYTCNGGNAARCAYAAYGGNATHTTYATHTTYTTYAGYMGNATH YTNMGNCCNTTYTGGGAYTAYCCNGTNACNACNGARTTYATHCAYGAYTCNAARCARGGN AARGTNTCNTTYYTNACNTCNAAYTTYAGYGTNGARGARYTNMGNACNGCNYTNGARATG GTNMGNGAYYTNTCNGAYTTYGTNGAYTTYAAYTCNAARTTYGAYGTNGAYTCNCAYATH GAYATHATGAAYACNGGNMGNGGNMGNYTNGAYGGNAGYATHGAYGARCARAGYMGNAAR MGNATGCARATGGARGTNCARMGNATGGARAARATGTCNYTNCARCAYYTNCARGARYTN YTNCAYMGNACNGAYGARGTNYTNGGNYTNTGGMGNYTNYTNATHGAYCAYCARTTYCAY ATHYTNGCNGCNGCNATGGCNCCNGAYATHCARAAYCARYTNMGNCAYATGACNTTYAAR ACNYTNGTNACNAGYGGNAARGAYGTNTGYAGYACNYTNATHGTNTGYYTNGTNAGYMGN TAYYTNAAYGAYAAYGCNACNATHGAYGCNATHAAYGAYMGNYTNMGNGARGTNTGYCCN ACNYTNTAYAGYACNGAYGAYGCNACNTGYTCNAARTCNAAYGARYTNYTNCARGCNGCN AARATHAAYCCNAAYAARYTNGARAARGARCARCARYTNYTNGARGCNYTNCARYTNYTN AARGGNGTNTCNCARCCNYTNAAYYTNTCNGTNATHTGYTCNCARYTNGCNAGYGTNCAR TTYTAYYTNGGNATHGTNGARYTNGCNYTNAAYGARGCNGGNAARYTNGAYCCNCARGGN ATGGCNGTNCAYTTYTTYAAYAAYGGNGARCCNCARGARGAYATHCARGGNATGCARGCN TAYATHGCNMGNATGGAYTGYTAYAARTGYATHACNGAYACNYTNTCNTAYYTNAGYGCN GCNAGYACNAGYCARGCNCARGTNCCNAAYAAYCCNTTYATGACNTCN---ACNAGYACN GTNGAYCCNAAYAARATHGARCCNCARCARGCNGARTAYTTYAARGARGARGTNTTYAAY ACNGCNYTNMGNTGYGAYGAYTCNYTNTTYCAYGCNTCNYTNTAYGARTGGYTNTTYAGY ACNAAYCARGCNGARAARYTNYTNGARATHAAYACNCCNTAYGTNGARCARTAYYTNMGN MGNAARGTNAAYYTNCARACNGAYAAYACNGGNGCNYTNGAYATGYTNTGGMGNTAYTAY GARAARGTNGARAAYTTYCCNGCNGCNACNMGNATHYTNTCNCARYTNGCNGARMGNCCN GGNACNAAYGTNAAYYTNACNCARMGNYTNGARTAYYTNTCNMGNGCNGTNGTNTGYGCN AARAGYTCNACNTCNMGNYTNGGNACNTCNGCNGGNGGNGARACNYTNCAYGARYTNGAR GARAARATGGARGTNGCNMGNYTNCARATGCARATHTAYMGNTGYYTNTGYAAYATGATG GCNGCNCCNCCNGTNGARAGYTCNAARGCNMGNYTNGAYGCNGARYTNATGGAYATHACN ACNYTNTAYGARGARTTYGCNGAYCCNTTYGAYYTNCAYGARATGAARYTNGCNATHGTN CAYTGYGCNGGNYTNTAYGAYGCNGCNYTNATHGARGAYYTNTGGMGNAAYATHATHGAY AARGARATHAGYAGYACNTCNCARATGTCNGGNTCNGAYMGNATHGGNACNATHGGNACN AARYTNACNACNGTNGCNAARYTNTAYGTNAGYGCNGARMGNTAYTTYCCNGTNGCNYTN ATHYTNMGNCAYYTNGARCARAARTCNTGYGARYTNGCNYTNGAYYTNGARTGGGTNTTY AARATGATGYTNGAYGTNGGNGTNGCNCCNGCNMGNYTNYTNGARYTNTAYGAYMGNYTN TAYAARTCNAARGAYGTNATHTGGCARACNYTNGGNMGNCCNYTNCAYGTNYTNATGGTN YTNMGNGCNTTYATHGAYCAYYTNGCNMGNAAYCCNATHYTNYTNAARGGNGTNAGYCCN CCNATGCARGTN---TGGTGYYTNGAYYTNGTNGCNTCNTAYYTNGTNGAYYTNGGNGCN YTNGGNACNTCNACNMGNGAYGTNCCNCCNYTNATGGCNGGNTTYAARGCNACNCARGCN AARYTNGARMGNYTNYTNTCNGAYATHATHGARAAYTTYGARAAYGTNGGNAAYAAYGAR GARYTNYTNYTNTTYACNCCNACNACNCCNAGYCCNGARGAYGTNAAYTGYCAYGTNGAR ATHCCNGTNACNMGNCARGTNGGNGGNMGNTGYGTNAAYYTNGGNACNTTYATHGGNTGY CARGCNGGNATHTAYYTNGCNTTYGAYGCNTCNTGY------------GAYCARMGNYTN TCNGGNCARGAYGGNTCNGCNCARCARCAYGGNAAYCARGGNCCNMGNMGNGGNCCNTTY YTNMGNMGNMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNAARGAYTTYCAYYTNGCNATHACNGTNGTNAARGGNMGNGARAARGTNMGNGARATG TTYYTNAARAAYAARCAYGTNACNGAYATHMGNGTNATHGAYATGYTNGTNATHAARGGN CARATGGARYTNGTNGARGCNGCNAAYATHTGGAARCARAARCAYCAYATHATGGCNTAY TTYCARGAYACNGTNAAYCCNAARCCNACNGAYTTYYTNGGNAARTTYTAYGARGGNCAR GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARTTYCCN YTNCCNCCNTGYMGNATHTGYAGYGCNCCNGGNGCNGGNTTYCAYTAYGGNGTNAAYACN TGYGARGCNTGYAARGGNTTYTTYCAYMGNAGYYTNAAYCAYTGGTCNMGNTAYAARTGY YTNAAYAARGGNAARTGYYTNATHCARCAYGGNCARGGNAARATGTGYMGNYTNTGYMGN TAYCARAARTGYYTNGARATGGGNATGTCNAARTCNGCNATHAARACNGGNMGNTAYAAY TAYAARAARAARACNGAYGAYATHYTNGARGTNAAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNATHCCNGTNGCNAAYTCN---TTYGCNYTNYTNAARCCN GARGARGARYTNGARGARGARMGNMGNGCNMGNMGNAARYTNGARCARAARCARCAYGAY GCNTCNGCNAARAARAARGAYGARAARAARCCNAARAARTCNAGYGARAARGARMGNYTN CARCARYTNGCNTTYGGNTTYGCNMGNCCNGGNTCNGCNAAYCCNGARCCNGCNAARCCN GCNTCN------GCNGGNAARAARAARGGNGAYTGGCARCARTGGAARGARCAYGAYAAR GARGTNGTNGARGAYCARTTYMGNGAYGAYYTNGARAARGCNYTNACNGARAGY------ CARCARGARCARAARAARACNGAYGAYAARCARAARAARGAYCARATGAAYGGNGGNCAR GARGCNTCNGCNCCNGARGARCARGGNAARAARAARAARAARAARGAYAARGCNAARACN ATGTCNYTNGARGARTTYAAYAAYYTNCARAAYCCNAARGCNCARAARGCNTCNGAYGAY CAYGAR---------------GARGTNTCNMGNCCNCCNATHCAYCAYMGNGTNCCNGCN AARGAYAARGAYTCNAARTTYTTYAAYAGYGCNCARCAYGARGCNAARCARATHYTNAAR AARGAYAARATGCARGARGARTAYMGNAARACNTGYGCNGTNGAYAAYGCNGTNGTNGCN AARYTNAARAAYGAYATHGAYACNMGNGAYAARACNATHAARGAYYTNAARCARAAYATH GARAARATGGARAAYGARATGAARCARGTNAARCAYMGNAAYAARCARYTNTGYGTNATH YTNGCNCARGGNGARATGAARGAYAARGCNCARGTNYTNYTNCARGTNGAYGARYTNAAY AAYGTNAARGAYGARYTNATGGARCARGTNACNTCNYTNACNGCNGARYTNGARAARGAR AARTCNAARAAYMGNGCNYTNAARACNGARGGNGAYMGNGCNAARACNGGNAARCAR--- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARTTYTGY CCNTAYGARTCNTTYTGYMGNTCNGAYGTNYTNMGNCAYATGGGNAARAARCAYGARGAR TTYGARGARYTNTCNAAYAAYYTNAAYTAYTGYACNTTYYTNTCNGAYTAYGTNMGNTGY AARATHMGNGCNGARGGNAARGARAAYAAYCARGCNGTNGAYCARGAYGAYGAYGTNGGN GARGTNGAYACNGAYACNATGAARGCNCAYGCNGARAAYAARCAYGARGGNGARGGNAAR TCNMGNAARAGYCARAAYCCNMGNMGNCAYCCNCARGTNAAYGARAARGAYTAYGAYACN TTYGARATGGARGTNGARGARATHGAYGARAAYGGNGAYTCNCAYTCNGARMGNATHYTN TAYCCNTCNTCNAAYTCNAGYGAYAAYMGNAAYCARTCNATGGGNTCNCAYATGCARYTN ATHCCNTCNYTNCARGAYGGNCCNCAYGGNTAYACNGCNACNCAYGTNTCNMGNCCNACN CARCCNCCNATHMGNGCNGGNMGNCCNAAYMGNGGNAAYAAYMGNGGNMGNACNGCNAGY GCNTCNAGYYTNTAYTGGAGYTGYGGNTAYTGYGAYTTYCARAGYAGYAGYCARGCNGAR ATHAARGARCAYTCNAAYMGNACNCAYCCNGGNAARCCNCAYMGNTAYGTNGCNYTNATH AARAAYATGACNCCNGAYTCNATHATHAAYAARAAYACNAAYTCNTCNCCNTCNYTNMGN AAYTCNGCN------------MGNTCNTCNTCNTCNTTYTCNTCNGTNAARYTNGAYAAY GTNGCNAAYMGNTTYGAYTCNGARGGNGCNGGNATGTCNGAYGAYATHGTNAAYYTNTCN AAYAAYGCNGAYGARACNACNYTNAARGTNAARATHGGNACNCCNMGNGGNCCNAARAAR GAYAAYACNACNTAYAARTGYTAYCAYTGYACNTAYACNGCNAARMGNCAYTCNTCNATG AARTCNCAYATHTAYTAYAARCAYMGNGGNAARGGNYTNYTNGCNGTNGAYGARGAYACN AGYACNGGNGGNCARGTNTTYTTYTGYGCNMGNGAYGAYTGYTCNTTYAARTCNACNAGY CCNACNTCNTAYYTNAAYCAYGTNGARCARTGYACNCCNTGGCAYAARCCNGARYTNGCN GAYGTNGARGTNGARCCNCAYATHMGNGARTGYYTNCAYCARACNGTNACNTTYGCNGAR ATGGCNYTNGAYAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CAYGAYATHGTNGCNYTNGCNAAYYTNMGNCCN GARCAYAARGAYGARYTNGAYAGYTAYATGTAYCARACNGTNGGNCAYCAYGCNATHGAY YTNTAYGCNGARGCNATGGAYYTNCCNYTNTAYGTNMGNACNATHCAYGGNTCNAGYYTN TCNATHGGNMGNGAYTAYCARCCNCAYGARGGNGAYGARGTNGARGAYYTNTTYCARYTN YTNTCNCARATHAARTCNGARMGNGAYATHGAYGCNGTNAGYGTNGGNGCNATHYTNTCN GAYTAYCARMGNGTNMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ACNAGYGCNGCNCAYYTNATGYTNAAYYTNAARCARACNAARGARAAY CARMGNAAYCCNGGNMGNCCNCCNYTNACNTGGATHACNCAYGAYACNAARMGNYTNTCN TTYGTNMGNAAYGAYYTNACNTAYACNAARGGNMGNATHGTNGTNCARTCNACNGGNGTN TAYCAYYTNTAYAGYCAYATGACNTTYTCNTCNCARGGNAAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TTYMGNATGTCNGARGAYGARAAYGCNTCNYTNMGNMGNAARATG GARYTNGTNAARAAYGARTTYGARGCNCARAGYCARYTNGCNGARGAYGAYYTNAAYMGN GTNTGYMGNYTNGARAGYCARYTNAAYGGNGCNCARACNGARYTNGARAARYTNGARAAR CARCARATHAAYYTNGTNCAYGARATHGCNATHGARATHGAYGCNYTNGTNGARACNGCN TCNATHGAYGCNACNAGYMGNTGYCARCCNATHAAYGGNYTNAARAAYYTNGCNACNATH MGNTCNGGNATHCCNAAYCAYYTNYTNACNGARATHAARAAYAARYTNAARTGGYTNMGN TCNGARTTYMGNGARMGNYTNGCNMGNGARMGNMGNYTNMGNAGYGARTTYMGNACNGCN YTNTCNTCNTCNGARGCNGAYMGNCARTTYYTNAGYGGNCARYTNGCNMGNAARGAYGAR GARYTNGAYGAYYTNGCNYTNGARAARCARGARATHGCNTAYAARGARATHCARTCNTCN AGYTTYGCNGARGARYTNGARGARCARGTNYTNGAYYTNTCNGAYGARYTNCARYTNMGN AARATHMGNGARGAYGARCARMGNAARATGTTYGTNMGNGARAARCARAAYATHYTNGAR GARATGGGNGAYATHATGGAYGCNGARAARGARAARGCNAARATHGARGAYMGNTAYMGN MGNYTNCARGARACNYTNAARTCNYTNCAYCAYGAYYTNAAY---ACNAARGTNGARAAR GGNAARMGNACNAAYGGNATHYTNMGNTCNCCNTCNCCNAAYGGNTCNTCNAARAARMGN AAYCAYGTNMGNATHTCNTCNACNACNCCNACNAARGARTTYGAYGCNGAYGARCCNATH YTNGCNACNCCNTGYCAYACNCCNCCNCCNATGGCNYTNACNGAYGAYGARTTYMGNTCN MGNTTYATGCCNCARACNCCNCARGAYATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG AGYGAYGARGAYMGNGARATHGAYATHGARAGYGAYGCNGAYGAYGARGAYGGNYTNAGY GCNTTYGCNTCNGTNGAYGAYAARMGNGCNCAYCAYAAYGCNYTNGARMGNAARMGNMGN GAYCAYATHAARGAYAGYTTYCAYAGYYTNMGNGAYTGYGTNCCNCARGAYGAYAAYAAR ACNAAYTCNAAYCCNGAYTCNAARACNTCNMGNGCNCARATHYTNMGNCARGCNTCNGAY TAYATHATHMGNATGMGNGAYAARACNTCNCARAAYGAYMGNCAYATHCARATHYTNAAR CARCARAAYGAYGARYTNCARGCNCARATHAARGCNYTNCARAARTCNCARTCNAGYGGN AARGCNYTNATHAAYTCNAAYTTYYTNGAYGAYMGNGAYGAYGAYGAYTAYGARAGYTAY GARGAYGARCCNGTNGTNGCNTCNCCNCCNAARMGNAARAARGCNAARACNAGYCAYAGY ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYATGATHGTNGGNYTNGGNAAYTTY CCNTAYCCNGAYACNMGNCAYAGYGTNGGNATGAARGCNYTNGAYGAYTTYACNAGYAAR YTNGGNYTNAGYTGGGARAARGTNCARGGNMGNCARGGNGGNCARYTNTGYAARACNGAR ATGGAYTTYTCNGAYCARGARYTNACNCAYATHTAYYTNTTYAARCCNAARTCNYTNATG AAYATHTGYGGNGGNAAYGTNGCNMGNACNGCNAARTCNYTNGGNGTNATGTCNGAYTCN ATHTAYYTNATHCAYGAYGARYTNGAYYTNGCNYTNGGNAARGTNTCNATHAARAAYGGN GGNAGYGCNAAYGGNCAYMGNGGNGTNYTNTCNTGYGTNAAYTGYTCNGAYGGN------ ---------------ATHATH---------------------------------YTNCCN MGNYTNMGNATHGGNATHGGNMGNCCNTCNTCNAARGCNGARGTNGTNCCNTAYGTNYTN AGYTCNATHCCNGTNCAYGARGTNAARGTNACNGARTCNGCNGTNGAYMGNGGNATGAGY YTNYTNYTNGAYCAYATGGCNAARMGNGTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARCARGCNCARGGNGTNAARGCNCARCAR CCNAARGARAARCCNACNGCNGCNMGNMGNGARGAY---AARGTNGGNGTNTCNGTNATG AAYGARTCNGTNCARACNAAYATGAARAARGGNGTNGCNCARGCNGCNCCNGARGCNCCN GCNGARTAYGCNYTNAARTAYAARGCNGGNGTNGCNCCNTCNMGNGTNATHAARAARTTY TCNGARTAYCARAARCARTTYCARTGGAARAAYGGNATGAARGCNTCNCCNYTNYTNGCN GCNGARCARATHGTNTAYACNAGYAAYACNGARYTNGGNCCNTAYAARAAYGARGCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYAAYTAYTTYGGNTAY GGNAGYAAYATGYTNGARGARMGNATHCAYATHAARAAYCCNTCNGCNAARTAYATHGGN AAYGGNACNYTNAARAAYTAYMGNTTYGGNTTYGARAARACNGTNGGNATGGCNGARGAY ---GTNGGNGCNATHGCNACNGTNMGNCCNACNGARAAYGAYGARGTNAARGGNTGYGTN TGG--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARTCNGGN GCNAARCARTGGYTNCAYCCNTCNACNGCNYTNYTNAARGGNCAYATHYTNTAYACNGTN AARTTYYTNGGNGARTGYAARGTNGAYCAYCCNAARGGNACNGAYGTNGTNAARGCNGCN ATHACNAARATGAARTTYAAYAARCAYATHAARMGNGCNGARGGNCARAARCCNCCNAAR GTNGARYTNACN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CARAARAAR AAYGTNMGNTCNGGNGGNGGNAARATGGAYTCNAARCAYTTYTCNTCNMGNTCNACNACN GAYAAYYTNCCNAGYTCNYTNAGYACNCCNGGNGARMGNGCNGGNYTNTCNTCNACNTCN CCNGCNACNGTNGAYACNTCNGTNACNACNTCNTCNGCNAAYTCN---AAYACNYTNTCN CCNCAYGTNGCNAGYCCNGCNGAYATHACNTCNCAYTCNACNAAYCCN------GTNATH GCNACNGARGCNGARGTNGAYACNTCNMGNYTNCCNCCNGAYGCNAAYGAYTCNGARTCN TCNCAYTCNTCNACNAGYGAYAARTCNTAYGAYCCNAARAAYGAY---CCNAGYYTNTGY TCNTCNTCNTCNAAYTCNTGYTCNAGYYTNGCNAGYTCNGCNGTNATHTCNTCNTCNTCN AARGGNCAYTCNAGYACNACNGAYGGNCCNAGY--------------------------- ---------------YTNTCNYTNCCNACNGCNAARAAYTCNATHACNTCNTCNAAYAAY GCNATHAAYAAYGGNCARAAYACNGCNGTNGTNGAYTCNATHGTNGGNAAYACNATHACN TCNTCNTCNAAYTCNAAYAARGAYAAYGTNTCNTCNGCNATHGARMGNACNGARGAYCAR AGYYTNTCNTCNTCNTCNATHCARCAYCCNAARTCNCARTCNTCNCARCCNCARTCNMGN CCNGCNGCNTGYATHGARGARTCNTCNCARCCNTCNCCNTCNGCNMGNGGNGTNAARMGN TCNCAYGARGARATHGARGAYATHAGYGAYTGYTCNAAYTCNCCNAARCCNTCNCCNCAR AARAAYAARAARMGNTGYTTYACNTGYAGYTGYMGNYTNGARYTNGCNCARMGNACNATH GGNAARTGYMGNTGYGAYCAYGTNTTYTGYCCNATGCAYMGNYTNCCNGARYTNCAYGAY TGYGARTTYAAYCAYAARGARGAYGGNMGNMGNGARGCNMGNGARAARATGGTNAARCCN ACNMGNCAYATGGGNACNTCNTTYMGNMGNGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGTCNGGNATHACNTGYYTNGCNTGYAAYGTNGCNTTYGARGAY GTNGARYTNGGNMGNATHCAYTAYAARACNGAYTGGCAYMGNTAYAAYYTNAARMGNAAR GTNGCNAGYYTNCCNCCNGTNACNYTNGARAARTTYGARGARMGN---------CARMGN GCNCARGARCARYTNGAYGCNGCNACNAARCARGARMGNTGYGCNTGYAARCCNTGYAAY AARTGGTTYAAYACNACNAAYGCNTTYGARAAYCAYYTNCARTCNAARAARCAYAARGAY GTNATHTCNGGNGTNGAYAARYTNAARAARGAYCARAARAARAARCCNGGNATHTCNCAR GTNYTNAARAAYAARGGNMGN---------------AARGGNGARGARGAYATGTCNGAR GAYGARGAYGAYTCNGAYGCNGARTCNTGGGAYAGYTAYGAYGARAARGTNATHGCNYTN GARGARTGYYTNTTYTGYTCNYTNGTNAGYCCNTCNATGGARGAYAGYYTNACNCAYATG ACNTCNAAYCAYGGNTTYTTYATHCCNGAYGCNGARTAYATHTGYGAYYTNGARGGNYTN ATGTCNTAYYTNGGNGARAARGTNGGNGCNGGNTGYGTNTGYYTNTGGTGYAAYGARAAR GGNAARMGNTTYCAYGAYTCNAARGAYGTNCARAARCAYATGGTNGAYAARGGNCAYTGY AARATHTTYCAYGARCARGARACNYTNTAYGARTTYACNGAYTTYTAYGAYTAYTCNAAR AGYTAYCCNGCNGTNGARGGNGARGAYCCNGARACNCARTCNGAR---AGYGTN---GAY ATHYTNGARYTNGAYGGNGAYGGNTAYTCNYTNACNYTNCCNTCNGGNACNGTNATHGGN CAYMGNTCNYTNGTNMGNTAYTAYMGNCARAAYYTNGCNCCNTAYMGNCAYGARAARACN AARACNGTNYTNCCNAARATGYTNGCNCAYTAYAARGCNYTNGGNTGGACNGGNGCNACN GGNCCNYTNGTNGARMGNMGNGCNAARGAYYTNCARTAYATGCARMGNGTNMGNAAYAAR CAYTTYATGMGNYTNGGNACNAARGGNAAYAAYYTNACNYTNMGNYTNMGNYTNCARAAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GTNGGNGGN AAYTTYYTNYTNCARMGNGTNATGAARGAYGTNACNCCNGGNYTNTCNGTNTTYATGCAR AARCARGCNAAYATHAGYTGYGAYTCNMGNTCNACNTAYATHCAYACNGCNAGYTTYAAR YTNCARYTNGCNATHYTNGAYACNYTNGGNCCNYTNGCNGARAARYTNGARYTNMGNGAR MGNAAYYTNGAYGTNATGGCNAARATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------TTYCARTTYCCNGGNGARGAYTAYGGNCCNGTNGAYTTYCCNAGYACN YTNCCNGCNGAYYTNCARGCNGGNATGGCNTTYGCNGGNGGNGGNCCNGTNTTYCCNCAR AAYCARMGNGGNGGNTCNTAYGGNATGCCNCCNTTYCAYATGAAYTAYTCNCARCARGCN TCNATGCCNTCNATGTCNAGYYTNAAYTCNAGYTCNTTYMGNAGYMGNTTYAGYGARTTY CCNTCNGAYCARAGYCCNCAYYTNCCNATGCCNATHCCNTCNCCNGCNTCNGGNATGATH ---GAYMGNYTNCCNAGYTTYAGYACNATHGTNTCNAGYAGYGGNGGNAGYGARYTNTCN AARAGYAGYCARGCNYTNTAYTCNAGYATHGCNACNTCNYTNTCNACNCARCARCAYTCN TTYCARCCNTCNTCNMGNAGYAGYYTNCARTCNCAYTTYGAYGCNTCNTTYCARGAYCAR GCNTCNTCNAARAGYTAYAGYAARTCNTCNCCNYTNGGNTCNACNTCNCCNGGNATGAGY AGYAGYAAYAAYAAYATHCCNCAYTCNTCNGTNATGCARGGNTCNTCNCAYAAYGGNAGY AGYCAYYTNCCNACNYTNTCNCCNMGNTCNTAYAARGTNGARAGYATHTCNCARCARGCN TAYYTNGGNGCNATGAAYYTNGARMGNCAYTCNGCNTTYCCNCAYGGNTCNYTNTCNGGN TCNCAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARGCNGARAAR---GCNAARAARATHCCNAAR MGNGCNCCNACNGCNTAYATGYTNTTYTGYAAYTCNCAYMGNCCNGCNATHGTNGCNGAR AAYCCNGGNATHGARTTYGCNGGNATHAGYMGNAARYTNGGNGARYTNTGGCARACNCAR TCNAAYAARCARAARYTNCARTGGMGNMGNAARGCNCARMGNMGNYTNAARAARTCNAAY YTNATHTCNACNGGNAARGTNGGNGGNAARGARTCNCAR---------GGNGGNCCNYTN ACNATGGCNGTNGCNCCNCCNYTNAGYTCNAAYAARAARYTNGCNYTNATGYTNCARMGN AGYAARCCNCCNGTNGGNGGNGGNGGNCCNYTNAGYCCNACNAARAAYTTYAGYATHGAR CCNYTNGAYGTNGCNGCNCAYYTNAARYTNYTNGGNGARTCNYTNAGYATHATHGGNATG MGNYTNCARGARCAYAARGGNATGATHGCNGTNCARGGNAGYYTNTCNGTNYTNYTNGAY TCNYTNYTNTGYGCNTGYGGNCCNYTNYTNTGYYTNACNCARCARGTNCCNGGNATGGAY GGNTGYTCNCCNATGGTNCAYGCNCARACNYTNGAYAGYGTNGCNTAYGTNATGCCNGGN YTNGARYTNTGYGCNTAYGCNGTNCARTCNGARYTNGGNGAYTTYGAYCCNMGNATGAAY ACNCCNGGNTAYGTNTCNGARTTYAGYTTYGTNCCNAAYCARACNGARGARYTNGARAAY AGYATHGCNGCNATGCAYMGNMGNTGYGTNGGNGCNACNCCNYTNATGGCNGARCAYMGN TTYYTNGARAARTCNAARTGGYTNGARATGTAYGGNGTNGAYYTNCAYCCNGTNAARGGN GARAGYTGYGTNGARTAYTTYYTNGGNYTNACNCCNACNGGNATHGTNGTNTAYAARCAY AARACNAARGTNGCNAGYTAYTTYTGGCCNMGNGTNACNAARGCNTCNCAYAARACNAAR YTNTTYATGGTNAARGTNAARGAYAARAGYAAYGAYGARCAYGTNTAYGCNTTYGARYTN TCNTCNAARTCNGCNTGYAARCAYYTNTGGAARTGYTGYATGGARCAYCAYACNTTYTTY MGNMGNCARCARMGNMGNGTNAAYTCNGARTCNMGNYTNAAYACNGAYMGNYTNTAYGAY AAYTCNGARGGNGGNYTNATHACNTCNATGGGNCARCCNCARCCNGTNMGNGCNTCNMGN CAYMGNTCNYTNCCNGARYTNCARGGNAARGARTCNCCNMGNAGYGTNAARTCNGCNCCN TGGGARTCNAARTAYGAYTGYGGNYTNTAYACNTCNGGNCAYGARTCNGARAAYGCNCAY CAYTCNMGNMGNATHMGNGCNATGTCNGGNAGYGAYAGYGARAGYGGNATHAGYCARMGN AARAARTAYTTY---AARATGAGYAGYATHCAYCCNAAYGCNCCNCCNCCNCCNTAYACN GGNGGNGAYCCNTCNTAYCCNCCN---CCNCCNGCNGGNTAYTAYGGNGCNCCNCCNCCN CARGCNTAYGGNGCN---GCNGGNTAYGCNCCNCCNCCNGTNGGNTAYGGNGCNCCNCCN CCNCCNGGNTAYGGNGCNCCNCCNCCNCARGGNTAYGGNGCNCCNCCNCCNCARGGNTAY GGNCCNGGNTAYGGNCARGGN---------TCNTAYCCNCARCARCARTAYCAYCCNCAR ------------GGNCAYTAYCARCARCARCCN---CARCARGTNGTNTAYGTNMGNGAR GARMGNMGN------GARAARGAYAAYAGYGCNGARACNTGYTGYYTNATHGGNYTNTGY AGYGCNATHYTNTGYTGYTGYYTNATG---ATGGCNGAYAGYAAYYTNCCNMGNCARGAY TTYGCNCCNCCNTGGYTNAARTTYCCNTCNGARACNGCNAARTCNGCNAAYCARAARTCN AAYTCNTAYCARGGNGAYMGNAAYMGNCCNMGNMGNGARGAYCCNTAYTAYTCNMGNTCN GAYTTYAAYMGNYTNCAYMGNCARAAYTCNTTYGAYTTYCAYGARGGNAARMGNTAYCCN CCNGGNCCNAGYAARTAYMGNCAYCAYTCNGTNGAYGAYGAYTAYGGNGGNTAYTCNTAY GGNTAYGGNTAYTAYCCNTCNACNTAYAAYTAYGARAARTAYGGNATGCAYTTYAGYTCN CARCCNTCNYTNGCNMGNTCNGGNAGYMGNGAYGGNAARTAYCCNCCNCCNGARCCNTAY TAYCARCAR--------------------------------------------------- ---GGNTCNMGNMGNGGNTAYCARGAYMGNGAYTCNCAYMGNGARGTNMGNAAYGGNGAY ACNAARGAYAARGAYAARGCNTCNGARAARGAYMGNCCNTTYAAYGAYGAYTTYCCNTCN YTNAAYGGNTCNGGNGARTCNTCNGTNGAYTCNAARGCNAARCCNGCNTCNGGNGTNTGG GARAAYCCNCCNAARTCNTCN---AAYAARAAYGARGARTCNACNGAYYTNYTNAARAAY ACNTCNCCNGGNATHTAYAARGCNYTNGTNCCNAGYAARAGYGTNCARCCNAARAARTCN GTNAARGAYGTNCCNMGNGTNAAYGGNAGYGTNMGNGARATHTCNCCNYTNAGYCCNTCN AAYAARGCNGGNCAYMGNGARGGNTCNMGNTAYAGYCCNACNCCNGAYYTNGCNATHGTN ACNCARCCNAARAARYTNGGNGAYAARAARAGYGAYTTYYTNMGNGCNATHMGNAAYGAR AGYTCNATHMGNAAYGGNGARATGTGYCARAAYCARAAYCARAAYGTNGAYMGNAARTCN GARYTNAARCARGAYTCNAAYGAYAAYAAYGTNAGYGAYGARAGYCARAGYTAYAAYCAY ATHAAYGGNGAYMGNCAYGTNGAYACNAAYGARAAY---YTNGTNAAYATGAARAARGGN GTNAAYGGNGARGTNAARGAYGARTTYATHAAYGGNGAY---------GCNYTNATHAAY CAYGTNGAYCAYATHACNYTNTCNGGNGARGARGARGARMGNMGNYTNYTNYTNTCNATG GGNTGGGTNGARGARGAYAAYACNGARTAYGARATHACNGARGAYGARATHMGNGARTTY CARAAYYTNYTNCARAAYCAYTGYCAYGGNCARAARAAYGGNYTNAARTCNTCNYTNMGN AGYGCNYTNGAYMGNAARTCNGGN------ACNGAYGGNATGYTNAAYGGNATHTCNTCN GCNGARGARAAR---------------ATHAGYCCNAARAGYTAYGCNGCNGGNAGYTCN TGYCCNGARYTNGCNAARGGNGTNYTNMGNYTNTAYAGYATGMGNTTYTGYCCNTAYGCN CARMGNACNMGNYTNGTNYTNGARCAYAARAARATHCCNTAYGARACNGTNAAYGTNCAY YTNMGNAAYAARCCNGAYTGGYTNYTNGARAARAAYCCNTTYGGNYTNGTNCCNATHYTN GARAARGAYGGNCARATHATHTAYGARTCNACNTCNACNTGYGARTGGYTNGAYGARGTN TAYCCNGAYCAYAARYTNGTNCCNGAYGAYCCNTAYAARAARGCNTGGGAYMGNACNYTN TTYGARAAYTTYGGNACNYTNACNGCNMGNTTYMGNATHYTNTTYAARCCNGARACNAAR GCNGARGCNYTNCCNAARYTNCAYAARAAYYTNAARTAYTAYGARGAYGCNYTNMGNCAR MGNGGNGGNCCNTTYTTYGGNGGNCCNGARCCNTCNATGYTNGAYTTYTAYYTNTGGCCN CAYATGGARMGNGTNCCNGCNATGGCNACNGTNGAYCCNATHATHGCNATHAGYGGNMGN GARTTYCCNCARYTNCARGCNTGGTTYGAYGCNATGTAYCARYTNCCNGCNGTNAARGCN ACNATGTTYGAYATHCCNACNCAYYTNCARTTYATGAARACNYTNGGNCARGGNAAYGCN GAYTAYGAYTAYGGNYTNTTYGGNMGNTAYCCNMGNGARTAYAAYCCNAARGTNCAYGGN CCNTAYATGCCNGGNMGNTTYTAYGGNAARCCNGAYACNCCNTTYGGNCARGTNAARYTN GCNGAYATGGGNGCNTGGYTNGGNMGNMGNAAYAARACNCCNGARGGNYTNTGGAGYGCN GCNCAYMGNACNTAYTGGMGNTGGGCNGCNAAYAAYYTNCAYGTNMGNTCNAGYGGNTTY GTNCCNGTNGGNCARGCNGCNATGGTNYTNTCNATHACNTTYTTYGCNYTNYTNTAYGGN GARMGNAGYYTNCARCARGARYTNGCNGAYYTNMGNGARGAYYTNGARTCNACNAARGAY GARYTNACNGARAGYMGNMGNGAYGTNGCNGARYTNAARTCNACNATHTCNGGNYTNGGN GAYGAYYTNAAYAARTAYAARCAYYTNCARGAYGARAGYACNGCNGAYYTNMGNYTNAAR AAYGARCAYYTNAAYGAYATGGARGCNGTNYTNTCNGARACNMGNCARCARYTNGTNATH GCNGARAGYCARYTNGARGTNTCNAAYGARAARACNGARGARYTNGARTCNGCNYTNGTN GGNYTNMGNCARAARTAYAGYCARGCNAGYACNCARATHGGNCAYYTNGARACNACNGTN AAYACNYTNCARGAYAARYTNACNGARAGYMGNAGYMGNGARATHGAYAARGARCARACN GGNGARCARYTNMGNTCNGARYTNGARGGNYTNGAYMGNGCNTAYTCNGARAGYAARGAR GARYTNAGYAARTGYGARGAYATGATHCAYCARYTNACNACNGARYTNGAYTCNTCNCAR AARGARATHAGYTCNTCNCAYAARMGNATHAARGAYYTNGARGAYACNGGNMGNGARYTN MGNGARCARATGCARAAYGCNCARCAYCARGCNYTNCARAAYGAYGARMGNGCNCAYAAY TTYGARAAYAARYTNYTNTCNTAYCARGGNGARCAYAGYCAYTCNGAYMGNGARTTYYTN CARAARGARGARCARATHAAYTCNYTNGARTAYACNYTNGARGARACNAARAGYGAYGTN GARATGMGNCARTCNACNATHGAYCARATGAARTCNGAYYTNGCNATHACNCARTCNGAY YTNACNCARGCNMGNGARGAYAARAGYGCNGCNYTNAARGARATHGAYMGNYTNGARCAR CARAGYCARCARYTNCARYTNAAYYTNGCNTCNGCNCAYCARMGNCAYAARAGYGARACN GTNMGNTTYGARGARCARGTNTCNTCNYTNGARMGNCARGTNYTNGARACNCARACNGCN YTNMGNAGYGCNGARTGYGARATHAAYAAYAARGARGARCARATHAARMGNAAYGARGCN GARATHGCNACNTGYMGNGAYGAYATHMGNAGYAARGTNGARGARATHGARMGNYTNGAR MGNACNYTNCAYGAYATHMGNYTNGARATGAAYCARACNAAYGTNCARTGYAARCARYTN GARAAYGTNATHGCNGARYTNAARTCNGAYGGNGARAAYYTNMGNAARGAYYTNAAYGAR GCNMGNYTNCARTAYAARGAYTGYGCNCARGARYTNGCNCAYCAYGARGARAARYTNAAY YTNATGGARCAYAGYYTNCARTCNACNCARGAYCARYTNAGYCARMGNGTNACNGARATH GTNMGNCAYGARCARAAYACNMGNAARYTNCARGCNGARYTNAARGCNATHAARGARMGN GCNGARGCNTAYGARGARGARATGGARGAYCARAARGGNATGATHGAYAARYTNMGNAAR GAYYTNGTNATGTCNAARGARGARTAYCAYTCNTCNGTNCARGARGGNATHGCNTAYAAR CARCARGCNCAYAARAAYGARYTNGARYTNAGYGGNAGYMGNGARCARGARAARATGYTN TCNGAYCARGTNGARCARCARGARCARATHYTNAAYCARYTNCARACNGARYTNMGNGCN GARMGNGARMGNCAYGGNGAYACNGTNCARCARYTNAGYGCNAGYAARAARAAYGGNYTN GAYYTNCARTCNGAYYTNGARGCNATGCARAARCARACNMGNGARYTNCARGAYMGNGTN AARGTNMGNGARGAYACNATGGTNMGNYTNMGNCAYGARATHGAYAAYATGCAYCARAAR AAYMGNGARAGYAAYGARATGATGGCNGARAARGAYGGNCARYTNMGNYTNGCNGARATG AAYYTNCARACNGCNCARAARCARTCNAARCAYCAYGCNCARGARATHGCNMGNTAYGAR GAYACNYTNGCNCARYTNCARACNGAYYTNGARAARYTNCARGARCARTAYMGNCAYTCN TCNTCNAAYYTNATGGARGCNGAYAGYAARGTNCAYGARYTNAARGTNCARYTNACNACN YTNCARGGNCAYCAYAARGARGCNATGGAYCARYTNACNGAYAARGCNMGNCARYTNGCN GGNATHAARACNGARGCNGCNAARATGGCNCARCARAAYAAYTCNATGAARGAYGARATH ATGATHTAYGAYGARAARGTNMGNAARYTNCARCAYGARYTNMGNAARTCNCARGARATH AAYAARGCNACNGARGARGARYTNCARCAYTTYGARGARMGNTAYACNAGYYTNCARGTN GAYYTNGTNTCNAGYCARGARAARCARAARCAYTCNYTNCARGARYTNTCNTCNAARGAR GARGARAAYGTNGTNGTNAARGTNGARYTNAGYTCNYTNCAYGARAARTAYAARAAYGTN AAYGAYGARGTNCAYAARYTNACNAGYGARYTNGARYTNACNAARCARAAYTAYMGNAGY GCNACNGARGARATHTCNGGNYTNMGNGTNGCNYTNGARGARTCNMGNGCNAAYGGNGAY MGNYTNCAYMGNGARAGYGARYTNGTNGTNCAYAAYGTNAAYACNTGGGTNCARGARCAR AARATGGCNAAYGARAARYTNGGNAAYAARATHMGNGARCARAGYAARTCNATHATGGCN YTNACNTCNGARAARGARTCNYTNYTNGARCARGTNTCNAARYTNCAYAARAAYTAYAGY MGNACNMGNACNGARYTNGARGAYAARACNATHGARGGNGARAARYTNMGNGCNYTNCAR TCNCAYTCNGCNCAYCARCARGTNATHYTNAAYCARYTNAARAGYMGNYTNGARGARCAY GARYTNGAYAARGAYTCNGAYYTNAARACNAARGTNGCNACNATHGARGAYYTNCAYAAY MGNYTNAARTCNAAYATHGARAGYATHCAYCARYTNAAYCARCARYTNAGYACNYTNCAR AARGAYAAYATHMGNYTNMGNAGYGARYTNGAYMGNGARATHTCNACNMGNCARAGYYTN GARATGCAYATHCARGGNAARGAYCARYTNGTNGARTCNYTNMGNTCNCARYTNGAYTCN AAYTCNTAYAARAARYTNYTNGARAARGCNGARAGYTAYAARGAYCCNGARAARYTNGTN MGNTCNACNYTNAGYAARACNGCNGARGARACNGGNGTNGCNGAYCCNCAYAAYYTNGAY AARTCNTAYTGGATHCARMGNGTNGGNGARNNNCARYTNTCNATHCARYTNCARCARAGY AGYGARTAYTGGTCNGAYAARGTNMGNGAYYTNTCNGARCARYTNGARAARACNMGNACN ATGTCNACN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATHATHTAYMGNAARATHCARGARGTNCARCARCARCARGARYTN CAYMGNCARMGNGARCARTTYCARCAYCAYMGNAGYYTNCAYAGYCARMGNAARGARGAR YTNYTNGARACNYTNMGNGTNYTNAARGAYAARYTNGARGARCARAGYAARACNYTN--- ATGGCNTCNACNTCNCCNAARCCNAARAARGGNATHYTNAARAGYTCNAAYAGYATHGAY CAYAGYAARAARGARATHGARTGGGAYGARATGAAYATHYTNGCNACNCAYCAYCCNCCN GAYAARGAYTAYGGNTTYATGAARGTNGAYGARCCNCCNACNCCNTAYAGYCARGCNGCN ATHTCNGAYGAYGARGARGGNTCNTCNACNMGNGARMGNAARGGNAGYACNGARMGNGAY YTNGGNYTNGAYCCNGGNGAYYTNGCNTCNMGNYTN---CARTCNGGNTAYGARGAYAAR GAYAARAARTAYGTNGAYGAYGAYGAYGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYYTNMGNATHAAYCARTTYGAYATHGGNGAR ACNATHGCNCARMGNMGNMGNMGNGCNGGNGTNTTYAARAGYCARTCNGGNCCN------ ---------------------------YTNCCNACNAGYAGYTAYCARGTNACNMGNATG MGNAAYYTNTCNGGNGGNAGYAGYGGNAGYACNGCNAGYGGNAGYAGYAGYGGNAGYTCN GTNCARYTNGAYAAYCARTAYTCNTCNACNGAYAAYAAYCAYYTNTAYTTYAAYTGYTAY ATHCCNCCNTTYGCNAAYTCNTCNGCNGTNCCNAARAAY------GARGAYTCNGCNTCN GCNTCNCAYMGNAARYTNGAYMGNAGYYTNAGYGAYAGYGAYAGYGAYMGN--------- ---------------------------TCNGGNAGYMGNTAYAARACNGARYTNTGYMGN CCNTTYGARGARAGYGGNTCNTGYAARTAYGGNGAYAARTGYCARTTYGCNCAYGGNGGN CAYGARYTNMGNAAYYTNGCNMGNCAYCCNAARTAYAARACNGARYTNTGYMGNACNTTY CAYACNATHGGNTTYTGYCCNTAYGGNCCNMGNTGYCAYTTYATHCAYGARGAYGAY--- ------AARGGNGARCCNTCNCCNAAR--------------------------------- ---CARAGYAGYAGYGGNAGYAGYAGYCCNTCNYTNAGYCCN------ACNYTNAAYGAY CARAAYAAYTTYTCNTAYTCNTCNGARTCNTCN------------CARYTNAAYAAYGAY AAYACNCARATHAAYTCNYTNACNGTNAAYATHAAY---TAYGGN---------AAYGTN GARYTNCARTCNYTNGARCAYCAR---TTYAGYTCNGCNYTNAAYYTNAAYMGNAAYTCN MGNAAYGTNTAYAAYAAYAAYAAY------------------------------------ ---------AARTCNGAYGARTAYGAYATHTTYAGYTCNATHTCNGTNTTYAAYGCNGAY GARGTNGTNGAYAAYGCNCAYCCNAARTCNTCNAAYTCNTAYTCNTCNTCNCAYTGYAAY CARAGYYTNGAYAAYTAYCCNGGN---TAYMGNAAYAGYACNAGYTCNCAYTAYAAYTGG CCNTCNACNATGTCNTCNCARAGYATHGCNCCNGTNGAYCCNTTYAAYTAYTCNCCNACN GGNTCNACNGGNTCNACNACNTCNTCNGGNTCNTCNGAYTCNGGNAGYGGNAGYGAYTGY AGYGGNAGYACNGARAGYYTNGTNAGYTCNGGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYTTYAARGTNATHGTN ATHGARACNGARGAYGGNCARYTNGARYTNGARTCNTAYATGYTNCCNAAYAAYTCNGGN GAYGGNGGNGGNGARACNAAYYTNGAYGAYYTNYTNACNCCNYTNTGYCARATHGARCAY CAYTCNGGNYTNATHTTYTTYCCNGAYAARAAR---TGYTTYAGYAGYAAYAAYAARMGN MGNGGNGCNAARYTNCAYGCNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARACNTTYCAYGTNATHCCNCCNCCNCCNCCNYTNATGGARAAY GTNTTYGCNGGNMGNMGNGAYGTNMGNGAYCCNAARTCNGTNCCNGARAARGARATHGTN AGYAAYAARGGNACNGTNMGNGGNTTYACNAAYMGNGTNMGNGCNGGNATHGCNACNTTY TGGGCNCARCCNGARGAYGARMGNAAYTAYMGNCARCARGARAARGGNAARATHATHGTN TAYGCNACNTCNATGAGYGTNGTNMGNGARACNAGYGARMGNTGYAARTCNGTNMGNAAY ATHYTNCARAAYCAYATGGTNMGNTAYGARGARMGNGAYYTNTAYATGAGYMGNGARATH CARTCNGARYTNAARCAYMGNYTNAGYCARGARGGNATGACNGARATHAARYTNCCNCAY ATHTTYGCNGAYGGNATHMGNATHGGNGGNGCNGGNGARYTNGARMGNYTNAAYGARGCN GGNGARYTNMGNGCNYTNYTNGARGGNTAYCARAARATHAAYGTNMGNTTYGCNTGY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TAYTGYAARAAY ATHYTNYTNAAYCARGTNGTNGARYTNAAYTCNYTNATHGGNYTNTCNTCNTAYAARYTN TCNAARGTNTAYGGNGTNACNCAYACNMGNATHYTNAARATHAAYTGYAARAAYAGYACN CARTCNGGNATHATHACNGARTCNACNAARTTYCAYATHTCNGCNGTNCAYAGYGARGAR TTYCAY------MGNYTNTCNYTNGARACNGARCAYGTNGAYYTNGGNGGNYTNGAYGCN GARTTYGARAARATHAARMGNYTNTTY---TTYGTNAAYMGNTCNACNACNAARTTYTAY MGNCCNCAYGGNATHYTNYTNCAYGGNCCNCCNGGNTGYGGNAARACNTCNTTYGCNMGN GGNYTNGCNAARAARTGYGGNGCNACNTTYTAYAAYGTNGARTCNTCNGAYYTNYTNACN TCNGAYTTYGGNAGYGGNGCNAAYACNYTNMGNGAYACNTTYCARAARGCNGTNGCNYTN GTNGARGARGGNCCNGTNATHYTNTTYYTNGAYGARATHGAYATGYTNTGYCCNMGNCCN GARGTNGCNAGYYTNGGNAAYMGNCARYTNAGYAAYTCNYTNATGACNGARATGGAYGAY ATHCAYAGYAAYAAYATHTCNAGYYTNYTNATHYTNGCNGCNACNAAYTCNGTNTCNAGY GTNGAYCCNTGYYTNMGNMGNCCNGGNMGNTTYGAYCARGARATHYTNATHAAYGTNCCN TCNGARGCNCARMGNYTNTCNATHYTNCARGTNYTNACNGCNAARYTNCCNYTNGCNTCN GAYGTNTCNTGYAARGCNYTNGCNCARATGACNCCNGGNTTYGTNGGNGCNGAYYTNMGN GGNYTNTGYGARGARGCNGTNAAYCAYACNCARAGYCARGAYTCNGARGARTCNACN--- ---GCNYTNAGYATGGARGAYTTYTAYCARGCNYTNCAYAARACNATHCCNTCNYTNAAR AARGGNACNGARTGYGCNGTNGAYTTYAARMGNGTNGARTGGGAYGAYATHGGNAGYYTN GAYGARATHAARGCNGARATHAARCARTCNATHGARTGGCCNYTNAARTAYCCNGARATH YTNGARMGNATGGAYATHCCNCCNGCNAARGGNATHYTNYTNTAYGGNCCNCCNGGNTGY TGYAARACNACNYTNGTNMGNGCNGCNGCNACNTCNTGYAAYGTNTCNTTYYTNTCNYTN AGYGGNGCNCARGTNTAYTCNGCNTAYGTNGGNGARTCNGARMGNYTNATHTCNCARGCN TTYCARAARGCNMGNGCNYTNGCNCCNTCNATHYTNTTYTTYGAYGARATHGARACNYTN GTNGGNAARMGNGTNGCNAAYGTNGGNAAYAAYMGNGTNCARGARMGNATHYTNTCNACN ATGYTNAAYGARATGGAYGGNGTNGGNAAYAARTTYGAYTTYAARATGGAYTCNGCNATH TCNGTNGARAGY---------------TCNGGNTCNGGNACNCARAARACNGARGARAGY AAYAAYATGGGNAGYGGNMGNAGYAAYAGYAAYAGYAAYAGYAGYAGYAGYGTNAGYYTN AAR---------GTNATHGTNGTNGGNGCNACNAAYMGNCCNGAYATGYTNGAYTCNGCN ATHYTNMGNCCNGGNMGNYTNGAYAARCAYATHTAYGTNCCNCCNCCNGAYGARCARGCN MGNAARGCNATHYTNAARATHTAYACNTCNAARATGTCNTGYAAYGAYGTNGAYGTNGAY YTNYTNGTNAAYAARACNGARATGTAYAGYGGNGCNGAYYTNAARAAYYTNTGYAARGAR GCNGGNYTNCARGCNGTNMGNGGNCARYTNGCNAAYAGYAARCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNGTNGCNYTNACNGAYGTNGTNCAY GARAARGARGARTCNYTNGCNCARCARAARYTNGCNGCNCARGTNYTNGCNAAYAARYTN AAYGARYTNGARAAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARCARATGAAYAAYMGNMGNAAYCARGARGCNAARYTNAARGAYGAYYTN GCNMGNMGNAARMGNGARTGGGARCARAARAARGARCARGARMGNAARGARCARAARGAR YTNMGNGARCAYGARGCNGARATHGTNGAYAARYTNYTNAGYAGYCARGTNTCNATHTCN GARACNGARAARGAYMGNATHATGAARGARCAYGARAARCARATGGTNAARYTNGARAAY AGYYTNACNYTNTCNAARYTNAARCARMGNMGNATGYTNGARGARAARATHGCNCARAAR MGNTCNMGNCARATGGAYGARYTNGARAARAARCARGCNATGGARYTNGARAARCARMGN MGNATHGCNGARAAYAAYGGNGARGAYGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARGTNGARCARGGNATGAGYGTNTTYYTNGAYGTNTTYMGN MGNGCNGAYAARAAYGAYGAYGGNTTYATHTCNTGGGARGARTTYGTNTCNTAYTTYGCN GAYGGNGTNATGGGNAARGARGARYTNCARACNYTNTTYAAYGARATHGAYTCNCAYAAY ACNGAYAAYATHGAYGTNGGNGARYTNTCNGCNTAYTTYTCNCARAARYTNGGNAAYTTY CARCARATHTTYGGNYTNGTNGARGARATGAAYAARAARATGACNGAYGTNYTNTTYAGY ACNGCNAARGTNTAYAARGAYTCNTCNMGNACNGAYAARTTYGTNAGYMGNTTYYTNATG MGNGARATHYTNAAYCARATGGGNGCNATGCARMGNCCNYTNGAYGCNGCNTCNGARGCN YTNGAYCARCARGCNMGNGARGARMGNTCNGAYATHCARCCNYTNGARGTNTCNGAYATH GTNAARAAR---TCNAGYGAYAGYGGNATHGTNCCNGGNMGNATHGTNMGNMGNGCNAAR MGNCARGTNAGYAAY------------------AAYAAYAGYACNYTNGGNAGYGAYGGN CARAGYATHYTNAAYGGNCARYTNGARAARYTNGCNAGYYTNGTNGAYAARYTNGARTGY AARATHAARTTYGARAAYTTYMGNGAYGARGARGTNGTNATGGCNMGNGAYGAYACNGTN YTNYTNGTNCARMGNGARTTYATHGTNAAYGARGARGGNATGGGNGARTTYMGNTCNCAR YTNMGNTCNTAYGTNGAYYTNACNCARGGNTTYMGNGGNTGYTTYAAYGTNAGYGTNMGN GAYYTNMGNTCNAGYCAYTCNTTYCAYGTNTAYGARGTNTGGTGYGAYGARGARCAYTAY YTNCARAAYTGYGGNAGYGARGCNACNTCNTGYYTNGTNAAYAARACNGCNGARYTNYTN GARAARCCNGARACNGTNAARTCNATGGTNATHCCNGGNACNTGGTGGAAYACNGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TCN GCNGCNACNGAYACNAAYAAYATHMGNCCNTGYMGNTCNTAYGARYTNATGGAYGCNACN AGYACNYTNGCNCAYCAYCCNGAYATHMGNYTNAGYGCNTCNAGYCCNGGNATHTAYGTN CCNCAYCAYGCN---MGNAGYCCNGTNMGNTCNGCNAAYGCNAGYAGYGAYGAYGGNAGY AGYGGNCAYGTNGCNAARGCNTCNTCNMGNATGGTNGAYGCNYTNACNGARGARAAYMGN ACNYTNMGNGAYGARYTNGCNGTNGCNACNGTNAARGTNTCNMGNYTNTCNAARTTYGAR ATGGARGTNCAYAARATGCAYGARGGNCAYGARTCNYTNYTNCARTCNCAYCARAARMGN GARAGYYTNTGGYTNGCNATGMGNMGNAARYTNGARGARMGNATHMGNTGYYTNGARGAR TCNAAYGCNGGNGGNCAYACNGAYGTNACNAARGCN------ACNTCNTCNGTNACNGAR TCNGAYYTNMGNTCNMGNYTNACNGARAARGARTCNYTNATHACNMGNYTNYTNACNCAR AAYCARGARYTNYTNGCNAAYMGNAAYCARYTNGARGCNGARAAYYTNCARATGACNYTN ACNYTNTCNGARCARMGNGCNCAYGTNGAYATHGTNGARAARGCNYTNGTNGGNTGYCAR GCNAARGTNYTNATGATGGCNGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYTTYGGNTCNTCNATH YTNGGNACNCARAARTAYTGGGARGAYGCNTAYGARAARGARYTNGARAAYTTYGARGAR ATHGGNGAYGTNGGNGARATHTGGTTYGGNGARGAYGCNCARGARMGNATGGTNAARTGG ATGTGYAAR---AARTCNATHCCNGARTCNTCNAARATHATHGAYYTNGGNTGYGGNAAY GGNATGYTNYTNYTNGCNYTNMGNCARGARGGNTAYACNGCNYTNACNGGNGTNGAYTAY TCNGARTCNTCNGTNAARYTNGCNCAYAARGTNTGYGARGCNGARGGNGTNAARGAYATH ACNTTYGARGTNTGYGAYATHYTNTCNTCN------GAYGARGCNAGYMGNMGNAARAGY GCNTAYGAYGTNTGYYTNGAYAARGGNACNTAYGAYGCNATHAGYYTNAARAAYACNGAR GAYCCNACNGAYMGNCARACNTAYGTNGAYCAYGTNMGNTCNYTNYTNAARCCNAARGGN CARYTNATHATHACNTCNTGYAAYTGGACNAARGAYGARYTNACNCARCAYTTYTGYAAR GCNTTYTAYYTNACNGAYGARATHCCNGCNCCNACNTTYACNTTYGGNGGNCARACNGGN CARAARGTNACNACNYTNATHTTY---------------ATHATHGGNTTYCCNGARGAY GGNATHTAYGGNTAYMGNTTY---AAYMGNAARTCNATHYTNCAYTTYYTNGARAARATH CCNGAYCCNAARGTNACNAARTGGAGYCCNTGYTCNGAYCCNACNMGNTAYGCNGAYTCN GARGTNCARCAYGCNATHAGYTGYATGGCNAARGARAAYAAYATGTAYGTNGTNGCNAAY ATGGGNGAYAAYGTNCCNTGYAAYGCNAGYGAYGAYCCNAARTGYCCNCCNGAYGGNCAY TAYCARTAYAAYACNGAYGTNGCNTTYGAYCCNGAYGGNAAYYTNGTNGCNAARTAYCAY AARACNAAYYTNTTYTAYGARTCNCARTTYGAYACNCCNAARCCNGARGTNGTNTAYTTY GAYACNCCNTTYGGNMGNTTYGGNATGYTNATHTGYTTYGAYYTNYTNTTYAARGARCCN GCNGTNACNATGGTNACNGARCAYAAYATHACNAAYGTNGTNTTYYTNACNGCNTGGATG GAYGCNYTNCCNYTNYTNTCNGCNATHGGNTAYCAYTCNTCNTTYGCNMGNGGNYTNGGN GTNAAYTTYYTNTCNGCNAAYYTNCAYATHCCNGCNTTYCAYTTYCAYGGNAGYGGNATH TTYACNCCNAAYGGNATGGCNAAYTTYTAYTAYAAYAAYAGYYTNAAYTCNCCNGGNAAR YTNYTNGTNTCNACNATHGAYGTNATG---AARACNAAYACNAAYATHAARAARGAYAAR AARYTNGARAARAARAAYTTY--------------------------------------- ------------------------------------------------------------ ---------------------------AAYGCNACNGGNGAYGARTTYCARGCNAARYTN TTYGAYGAY---ATGTTYACNTTYAARGCNYTNGARAAYACNTCNGGNAAYYTNAGYGTN TGYCARMGNAAYGTNTGYTGYTCNYTNACNTAYAGYYTNYTNGAYMGNCARCAY---CAR GAYYTNTTYGCNTTYGGNGTNTAYGAYGGNYTNCAYACNTAYCARGGNCARTAYTAYTTY CARATHTGYACNYTNGTNAARTGYGCN---AAYAAYGAYGAYMGNCARTCNTGYGGNTCN CCNACNAARGTNTCNAAYACNAARTTYAARTCNYTNTCNATGACNGGNAAYTTYCARACN AARTTYGTNTAYCCNCARATHATHYTNTCNAARAAYGARCARYTNYTNYTNGGNGAYGAR AARTCNTGGAGYTTYCAYGAY---ACNACNYTNACNTCNGGNTCNGAYYTNGAYGAYCCN GTNYTNAGYGCNACNYTNTAYGGNMGNTAYTAYTGYMGNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MGNMGNGAYATHACNTTYTGYCAY GAYTAYCARAAYAAYGGNTGYACNMGNGGNAAYTGYAARTAYYTNCAYTGYACNMGNGAY GARCARGARTGGTTYCAYMGNACNGGNYTNYTNCCNGCNMGNYTNAAYCARACNTTYAAY TAYGGNAGYCCNGARCCNCCNMGNGTNGAYACNCCNTTYTGYAARGAYTAYYTNCAYGGN GARTGYAARMGNGGNAAYAARTGYMGNTAYMGNCAYTGYMGNGGNGARTAYGAYTGYAGY ATGAARMGNGGNGGNCARTGYAARTAYMGNCAYATGTCNGAYCAYGGNTTYGAYMGNGGN AGYGARATHAARMGNMGNMGNYTNGAYGAYGAYTAYGAYMGNGAYMGNTCNGAYYTNAGY TAYTCNTAYYTNGARGARGARAAYGGNACNYTNMGNAARAARGTNGAYGARYTNAARAAR CARGTNGTNGAYYTNACNGCNATH------------------------------------ ---------------------------------------------TAYCAYAGYYTNTCN YTNGCNTCNMGNGARTTYATHGAYMGNGTNACNTCNATGGGNTTYATHMGNGCNAARGTN GCNMGNGCNGTNGARAARTTYGGNCARGAYGARAARGARGTNYTNGAYCAYYTNTTYGCN GTNGAYATGYTNGTNGARAARAARTAYGCNCCNATHCAYGTNGARGCNGCNYTNCARTCN TGYAARAAYGAYYTNGARAARGCNGARAAYTTYYTNAARYTNCARGCNCARTTYGARCAR YTNGGNTAYAGYAGYGARACNGTNMGNGAYGCNYTNGTNTCNTCNGGNATGGAYCAYGAY AARGCNYTNGAYATHYTNACN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AGYGAYATHGCNTAYCAYYTN ATGAGYTAYTTYYTNATHTTYMGNTTYAAYTAYYTNGAYYTNATHCCNMGNGAYYTNATH AARAARATHYTNCARAGYTTYACNTCNYTNMGNAAYMGNAGYMGNATHGGNCARACNGCN GARATHATHGCNACNCCNTTYGGNTCNYTNTGYCCNGCNGTNTTYTTYAAYGGNTAYAGY MGNGGNGTNGTNAGYAAYGTNAGYGGNGTNAAYCAYTGYTGGATHGTNACNGAYGCNMGN TGYATHCCNGGNTGYGARGGNGGNCCNYTNTAYACNAARMGNAAYYTNAAYGGNACNGAR AGYTTYYTNACNGGNATHATHACNTCNCCNYTNTGYTGGAARAAYAAYGARTGGGTNGGN TTYTCNGTNGCNTGYAGYATHGAYAGYGTNYTNAARTCNYTNACNCARCAY---CARGAR ATHATHCCNAARMGNAGYCAYAARTAYYTNACNACNMGNAARCARAAYAAYGAYAAYYTN CCNGAYMGNGAYGCNGTNCAR---------------------------GCNMGNGCNATG ACNGTNYTNGTNCARTGYGGNAAYACNTGGGGNACNGGNGTNATHATHGAYMGNGAYCAR GGNGTNATHYTNACNTGYAGYCAYGTNGTNAARGGNAARAAYTCNAAYTCNGTNACNGTN ACNCCNTCNGARAGYACNMGNCARCAYMGNGCNGARGTNGTNTAYMGNCARGAYCCNYTN MGNACNCCNTAYGAYATHGCNGTNATHAARTGYGTNCCNGCNACNCARCAYYTNCCNAAR GGNTGGTGYGTNGAYGTNGCNCARGCNTGYATHGGNGARGAYATHGTNYTNTCNGGNCAY GCNGTNTTYAGYACNGAYATGCAYYTNGARCCNTCNATHTGYCARGGNGTNGTNTCNAAR GTNYTNMGNAGYAARAGYCARCCNGTNATGGTNCARACNACNTGYGCNGTNCAYGCNGGN TCNAGYGGNGGNCCNYTNYTNACNCCNGAYGGNMGNYTNGTNGGNATHGTNGTNTGYAAY ACNMGNGAYGCNTCNAGYAARACNAGYTTYCCNCAYYTNAAYYTNTGYGTNCCNATHTCN ACNGTNTGGCCNGTNATHTCNGAYTAYYTNGCNAAYGGNGAYAARCARGGNYTNTCNMGN YTNAARGTNCARGAYGTNGARYTNAAYCARYTNTGGGCNYTNGGN---------ATGGCN GAYYTNTCNYTNGAYGARTTYATHMGNCARAARAAYGTNAARGTNCARATHMGNAAYCCN CARCARAAYCARGCNMGNGGNCCNCARAAYCAR---MGNAARGGNGTNGGNGTNAAYACN AARCCNCARGCNAARCCNGTNCARMGNACNTTYGAYGCNMGNTCNAARYTNGCNCCNAAR ACNGTNGTNGAYGCNMGNGAYAARATHATHATHAAYAARAARAGYGGNAARGGNGAYGCN MGNAAYAARATHGTNCARAARCARGTNCARAARGGNACNTTYGAYGCNMGNTCNYTNYTN AARAAYCCNAARCAR---------ACNAARAAYAARCARAAYGGNGCNGTNAARAAYCCN CCNMGNCCN---------YTNYTNGGNTTYCCNGGNCCNYTNACNMGNACNYTNTCNAAY CCN------------------GGNAAYYTNCARGTNACNMGNCARGTNCCNGGNACNGAR GTNACNYTNACNMGNGAYTCNATGCARATHACNAARMGNGGNGTNGGNCCNCCNCCNYTN GCNCCNTCNATHGGNGAYGCNGTNCCNATHATHCARATHMGNAAYGAYMGNTAYCARCAR CCNCCNCCNCCNCCNCARCCNTCNTGGTCN---------------AGYCARCCNTCNCAR CAYGCNCCNCARCCNGCNCAYGTNGGNATGCARTAYTCNCAYCAYCAYAGYAGYTCNTCN GCNMGNCCNTCNTAYATGTCNTCNTCNCARGCNCAYMGNTAYCARGAYYTNGAYAAYCCN GARTAYAAYAAYAARTCNTCNATHGGNGTNCAYAAYATHCCNAARATGCAYATHTCNAAY ATHAARGCNGTNGARGCNGCNGGNATGMGNCCNGTNTCNTCNTCNTCNACNMGNTCNMGN CCNGCNCCNATGCARCCNMGNGCNCCNCCNGGNGCNGCNACNYTNTCN------------ GCNAARCARCCNATHTCNYTNTCNCARCARTCNTCNTCNGGNGCNYTNAARMGNMGNCAR CARGTNGCNCARGARGTNGTNGGNGGNCCNYTNMGNYTNGGNAARGGNGGNGGNCCNGGN YTNCARGTNGGNATHGGNGARGTNTCNCCNCCNAARMGNGTNAARCCNGGNGCNATHTCN ------GTNGARCCNATHGARATHYTNGAY---GARGAYTAYTCNAARTTYGTNAGYCCN ATHCARGGNTTYMGNGTNGTNGTNACNAAYYTNTTYTCNGGNGTNACNCARGAYGAYATH ATHGARYTNTTYGGNGTNGTNGGNCCNYTNAARAARGCNMGNYTNYTNAARGCNGGNTCN GCNGARGTNGTNTAYACNGTNMGNGARGAYGCNTCNAARGCNGTNCARAARTAYCAYGGN MGNGARYTNGAYGGNCARCCNATGTAYGTNAARATGACNACNCCNTCNACNGCNGTNGTN AARACNCCNCARGGN---TAYGAYCCNGAYATHACNGGNGARGCNYTNAARYTNTAYAAR AARCCNAGYAGYYTNGGNGCNYTNCCNGARGCNCCNATHGARGTNCCNACNATHCAYMGN GCNYTNTTYAARGTNGGNCCNCCNGCNCCNAAYAARTCNGTNAARTTYACNGTNAARATH ---------------------CAYYTNYTNMGNGARAGYATHYTNTCNCAYCARTGGACN GAYGCNATHAARATHGTNCAYACNYTNGTNAARGARGAYAGYATGGCNGARATH---ATH TGGAARGCNGGNATGGCNTCNYTNATHMGNGARAARAARATHAARTCNATHGAYYTNTAY GCNMGNCARYTNTGYAGYAAYACNAARYTNACNCAYGTNGARGTNYTNTTYGAYTAYYTN YTNTAYYTNYTNACNGARGGNAAYYTNGAYACNGCNAARAAYYTNACNCARGAYYTN--- ------AGYGARATGAARGARGTNAAYAGYGCNGARATHGARTAYYTNAARYTNYTNTTY MGNGCNTAYYTNGGNYTNATHGAYTAYATHCARTGGAARGARACNGTNCARGARGAYGCN GARGAYGARACNGCNGTNGAYTTYATHTCNTCNCARYTNTCNCARGGNTTYTCNCAYCAR TCNTCNAARGTNAARGCNGARAARGCNATHCAYAAYYTNTCNTGYGTNMGNGGNATHCCN GGNGTNTGGGAYATHTTYATHGTNAARATGGTNGARATHCAYGARTTYTAYAAYGARYTN GARACNGCNMGNTCNYTNYTNAARGAYTAYAARGCNACNAAYCCNGAYAAYYTNAAYGCN CAYMGNTAYYTNTAYAARTTYGARATGAARCAYAARGARAAYGCNGAYGARAARYTNCAR AGYYTNAARAGYATHATHMGNYTNGAYCCNAGYAAYCCNYTNGCNYTNGARYTNTAYAAR GAYYTNGARTCNTCNGAYCCNGARGCNGTNTCNATHYTNTTYGAYTAYYTNGAYTTYCAY CAYTGYAARAAYGAYYTNCARGCNTGGAARYTNYTNAARACNCAYYTNTCNGARGTNAAR GGNAAYGAYCARACNCAYGARGCNGTNACNMGNTGYTGGGCNYTNMGNGTNGAYTGGTGG ------------------------------------------------------------ ---AARAARTCNCCNGAYTGYAARACNTGYAARGARATHGTNGAYAAYTTYCAYAARGGN YTNTCNGCNACNGCNAARTCNAAYTAYGGNGGNGGNAAYACNAAYTGGGARGARAARTCN YTNGGNTCNTAYGCNTTYAGYGARGTNMGNYTNGTNGARATHATHGARAAYYTNTGYAAR GAYAARTCNAARGARTGYAAYACNATGYTNGARGARCAYGARGAYYTNATHGARAGYTTY TGGTTYAARGARTAYACNAARAARTCNGGNAARGAYTTYCAYTCNTTYYTNTGYATHGAR AAYATHAARGCNTGYTGYTCNCARAAYACNTAYGGNAARGAYTGYCARCCNTGYCCNGGN GGNGTNGARMGNCCNTGYCAYGGNAAYGGNAARTGYAAYGGNGARGGNACNMGNYTNGGN ACNGGNAARTGYMGNTGYAGYTCNGGNTAYAARGGNGARYTNTGYGAYGARTGYAAYGAY GGNTAYTAYGARGARAGYAARAAYGARACNCAYAAYGTNTGYAARGTNTGYCAYATHGCN TGYAARGGNAGYTGYTCNGGNGARGGNCCNAARGCNTGYGARGARTGYAARGAYGGNTAY GTNCARGAYCCNCARCAYGGNTGYAARGAYACNGAYGARTGYYTNGARGARCCNTGYGAY GAYGARCARTAYTGYACNAAYACNATGGGNTCNTAYTCNTGYTTYAGYTGYAAYGCNGCN TGYGCNTCNTGYACNGGNTCNGGNCCNGAYAARTGYAAYGARTGYAGYACNGGNTTYTAY AARYTNGAYAGYGGNMGN---TGYGARGAYGARGAYGARTGYAGYYTNGAYCCNACNYTN TGYACNAARTCNAAYGARGARTGYYTNAAYATHGCNGGNAGYTAYGARTGYATHTGYTCN TCNGGNTAYGARTAYAAYAARGAYAARGARTGYATHAARACNCCNAARGAR--------- ------------------------------------------------ATGGGNGGNACN GARAGYAARMGNMGNGTNGTNGTNGARAAYGTNAAYGGNGARGCNGTNGTNCARYTNACN GAY---GCNGTNGTNMGNMGNGTNAARGGNCARCCNGAYCCNCCNGTNCARAARGCNCCN MGNGARTTYAARCARGARAARGARCCNTCNAAYAAYGARCAYMGNCCNCCNMGNGAYGGN GARMGNTTYAAYTCNATGAGYAARGARATHGARGAYTTYTAYATGGARAARYTNAAYGAY YTNCARMGNAARAGYCARGCNYTNCARGAYACNTCNAAYGARCARTTYGCNAAYGCNGTN AARGARGTNGARCARAARTTYATGAARTAYACNTCNTCNCCNGTNTGYCARGAYYTNCAR AGYAARGTNYTNGARTGYTAYCARACNAARCCNGAYTCNATHYTNGAYTGYTCNTCNGTN GTNAAYGCNTTYACNACNTGYGTNGAYMGNGCNMGNATGACNGTNTCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYCCNMGNYTNGCNTCNGTNATHTAYCARAAYYTNGGNGCN ATHTAYAAYTAYATGGGNMGNTTYGARGAYGCNGTNAARTTYCAYGARAARGCNTGYCAY ACNTTYGCNAARYTNGGNATGMGNACNAAYCARGGNCAYTGYTTYACNAAYATGGGNTAY GCNTAYAGYCARYTNAARGAYATGGAYAARGCNGGNGARTGYTTYYTNCAYGGNYTNCAR GCNGCNMGNGAYTGYGGNGAYMGNAARACNGARTGGCARAAYYTNGARGCNYTNGCNAGY GTNGCNTTYCAYAARAARAAYYTNAARAARGCNGARCARCAYTAYCARCARGCNATHGCN GTNYTNTCNCARTCNCCNGARACNGCNGAYCCNGCNGTNCAYGARMGNYTNGTNACNAAR YTNAARAGYGTNATHAARGCNCARGCNCCNCCNCCNCCNCCNMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TGGCAYCAYCARATGGTNTAYGGNGTN AGYCAYCARGGNYTNTAYYTNACNAAYCCNYTNGARATHGTNTCNGARMGNTCNGCNGTN AARCARYTNCAYAGYGAYTCNGTNYTNYTNGTNMGNMGNCARGAYATHATHTCNMGNTTY MGNGARTCNACNGAYYTNGGNCARYTNYTNGAYCAYCCNGAYCCNMGNTGG--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TTYGAYGTNAAYGAYGTNTCNAAYYTNMGNCAYGTNATHATHGAYGGN AGYAAYGTNGCNATGAGYCAYGGNCARAARGTNTTYTCNTGYYTNGGNATHAARATHGTN GTNGAYTGGTTYAARAGYMGNGGNCAYAARAAYATHACNGTNTTYGTNCCNCARTGGMGN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GARYTNTCNYTNGAYTGYGAYGAYGAYGAY GAYGCNGTNTCNAAYATGACNMGNGAYGTNTGYGCNGAYATGYTNGARTCNATHCARAAR YTNMGNGARYTNGARCCNAAYAGYTCNAAYATGAARAARTTYYTNGARATGGARAAYCAR ATGAAYGCNYTNCARAGYTCNYTNGGNAAR---------TCNMGNMGNTCNAGYTCNAAY GARCCNGARMGNGARGGNCCNAARCARACNAARYTNACN--------------------- ------------------CCNGCNGARAARMGNCARMGNGARATGAARTAYYTNGARGAR MGNYTNGAYGARGCNGCNAARACNGARMGNYTNAARGARGARCARMGNMGNCARCARMGN GARYTNGAYYTNCARAARAARAARGARTTYGAYCARAARAARAARTCNCARTGGGTNAAR AAYATHYTNTCNGAYTTYAARAARGARGARGGNATGGTNGGNGARMGNATHAGYGCN--- ------GAYGCNGARAARATHYTNMGNCARMGNGARCAR------MGN------------ ---ATHCARGARAARGARGARGARGARAARCARMGNAARGCNGARGARATHMGNAARMGN GARGARGARGARMGNYTNCARMGNGARCARGARGARAARTAYAARGARGCNGARMGNAAR MGNYTNATHGARAARATHGARGARACNMGNYTNMGNGAYTCNAARAARTTYTCNTCNTCN CARYTNYTNTGGAAYCCNTCNTCNAGYAARGCNGTNAGYMGNAARATHGAYCAYGGNGCN YTNGCNTCNTCNACNTCNAGYMGNTCNGCNGAYMGNCARTAYTCNTCNAAYMGNGAYGAR TTYGAYAARGGNMGNATHYTNTCNGARAARGARTAYAARTGYYTNGCNGCNAAYGAYCAR YTNCAYACNATHCCNGARGGNAGYYTNAARGTNCARGTNGCNAGYTAYCCNAAYMGNYTN TGYCCNGTNCAYGGNTGYCCNTCNAARACNAAYTTYMGNGAYATGGTNTCNTTYATGGAY CAYTGGGTNATHTTYCAYCARGCNCARACNGCNATGAARTTYTGYCCNMGNTGYTCNGCN TAYTTYATGAAYCARAAYGARYTNGARAAYCAYATHATGAARCAYCAYTCNTCNAARGAR GCNAAYGARYTNATG---------MGNAAYGCNMGNGTNAARGTNATHCCNAAYCCNAGY TAYMGNGAYCCNTAYCCNTTY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AAYATGATH GAYMGNTTYGAYGTNMGNGCNAAYYTNGAYTTYATHACNGARTAYGAYCCNAARAAR--- TCNTCNAGYACNACNAAYGTNCAYGARCARGARGARMGNYTNTCNAAYTAYGARMGNTAY MGNACNYTNGTNGARAAYGARGCNTCNGGNYTNTCNGARGARCARTCNYTNCAYCARATH TAYYTNGAYGARCAYTTYGGNACNATHAAYAARCCNAAYGARGARGARAARAARAARAAY GCNGAYAARAARGCNGCNATHGGNTAYGTNTAYGARGAYAGYACNCCNGTNGARAARAAR GARGARGARAGYGARGARGARGARGARAGYGARGAYGAYYTNGAYATGGCNGAYYTNGAY GTNACNATHGAYGTNGAYACNYTNACNCCNGAYGTNTGYAARGCNGTNAAYGGNATHGCN GGNCARTAYGGNATGGTNGAYGAYGAYTTYGTNMGNYTNYTNMGNAARGAYAARGARGAR YTNGARGCNYTNAARGARGCNMGNCARYTNGARGARGCNAARGCNCARTTYTCNGGNMGN AARTCNMGNMGNGARMGNMGNGCNATHAAYGARAARMGNCARAAYCCNCARMGNTTYTGY MGNCCNAGYTAYGCNGCNMGNGAYAGYCCNAARTAYGARCCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNYTNTGYGCNATHYTNAAR YTNGARCAYCAYGARAARGCNAGYAARCARACNGGNGARTGYYTNGTNTCNYTNAGYGGN GTNGARGCNMGNATHGARGAYMGNYTNAARGCNTAYAARGCNAARAGYGTNACNGAR--- ------AGYYTNGAYTAYAGYACNYTNMGNGARGCNGGNATGGCNTGYCAYCARATGMGN ACNTGYYTNAAYGAYATHTCNMGNATHATHTCNYTNGCNTGGATHACNGARYTNCCNTCN GCNGGNGAYCARAGYMGNGAYTTYGAYCCN------------GARACNGARAARYTNMGN GGNGARYTNTCNGARYTNCARTCNAARTAYAGYGTNYTNGARACNACNYTNAARGARCAR CARGGNAARYTNAAYGTNTCNAARCARMGNCARAARGAYTGGGARCAYTCNGTNTGYMGN CAR---------AARAGYAARMGNTCNMGNAGYYTNTCNGARTCNTTYGAYGAYYTNAAY GTNATGGARAARGARYTNGGNGARTCNTCNGARGAYMGN------------GARATHACN GAYTGYMGNGAYGTNGAYMGNGAYAARATHYTNCARATHAAYAAYACNAARATHYTNAAY CCNGARGARMGNGGNCARTAYGARCARATHAARMGNGCNTAYGCNAAYATHYTNTAYAAR TGGGGNYTNYTNAAYCARMGNGCNCARGTNYTNAARCAYACNGTNTCN------GTNCAR AGYAARAARATHGARTTYTCNATHCCNTGYTCNAAYTGYTCNGAYACNGTNAARCARGTN CARTGYGAYMGNTGYMGNTAYCCNTCNYTNAAYTGYGCNATHTGYCAYATHGGNGTNMGN GGNACNGCNAAYGTNTGYCARGCNTGYGGNCAYGGNGGNCAYGCNAGYCAYATGATGGAY TGGTTYCAYAGYAAYACNYTNTGYCCNAGYGGNTGYGGNTGYYTNTGYYTNCARGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AARGAYMGNATHMGNMGNATG GARGARAARGARGAYMGNYTNCARGARGCNYTNACNGCNACNAGYCARGARMGNGAYGAY YTNYTNGAYCARYTNTCNTCNATGGARACNTCNYTNGCNTCNCARGARGCNCARATHAAY MGNYTNYTNAAYGAYGTNAAYTCNGARGAYGCNMGNTGYCARGARYTNGARGTNTCNAAY MGNCARYTNAARGARCARYTNGARYTNATGACNGARCARYTNGTNGGNYTNGARAARGGN AARTTYGAYAGYATGGARGTNAARMGNGARMGNGAYGAYYTNMGNYTNGARYTNAARGGN CAYMGNGCNATGGCNAARGAYYTNATGGCNYTNYTNAARGCNYTNCARCARGCNAGYACN CCNAAYYTNGCNGAYGAYAGYGGNAAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GGNGGNAGYGGNTAYGGNGGNGGNCAR AGYGGNGGNAGYTAYGGNAGYTAYGGNGGNGGNTCNAGYTAYGGNGGNGGNTAYGGNGGN AGYGGNAGYTTYGGNCAYGGNGGNAGYGGNATHGGNGGNGGNATHGGNGGNGGNYTNGGN YTNGGNGGNAGYGGNGGNCAYGGNAARGGNYTNCAYYTNCCNAGYAARGTNAGYTAYAGY CAYGGNTAYACNAARTCNCCNYTNATHTCNTTYGTNAARGGNTTYAARCCNGGNAARATH TAYGTNGAYAARGGNCAYGTNATHMGNAAYTAYTTYMGNCAYGGNACNTAYAAYGTNGCN GTNCARCAYTAYAARYTNATHCCNACNGTNAARGTNGTNCCNTAYACNACNTAYAARAAR ATHGGNGTNGGNCARAARGTNCARGCNAARTAYCARTAYAARGCNGTNATHTGYAARTAY TGYTAYCAYGGNTAYCCNAARATHGAYGTNTAYGARATGAARAARCCNTAYAGYTAYGCN GTNAARMGNTTYGTNTAYYTNCCNAAYGAYTAYAAYYTNGGNGGNAAYGGNCAYGGNAGY GGNTAYGGN---------AGYTAYGGNGGNCARGGNTAYGGNAAYNNNNNNNNNGGNNNN GGNCARGGNGGNGGNCARAGYTAYGGNGGNCARGGNTAYGGNTAYGGNCARAGYTAYGGN GGNCARAGYTAYGGNAGYTAYGGNNNNGGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNGCNGAYGTNATHGTNACNGARMGNGARGARGCNYTNTCNTTYYTN GARACNGCNATHTCNACNAAYAARGTNGGNAARAAYTGGMGNGTNAARGCNGARGTNYTN GAYTGGACNCAYMGNATHGAYATHTCNAAR------TGGAGYCAYTTYGAYYTNGTNATH GGNGCNGAYATHGTNTAYATHGARAGYACNTTYCCNCAYYTNYTNMGNACNATHAARTCN GTNGCNGCNTCNTCNAARACNCARGTNYTNYTNTCNTGYMGNATHMGNTAYGAYMGNGAY YTNMGNTTYYTNCAYATGYTNMGNAARTTYTAYTCNGTNGARGARATHTTYTAYAAYTCN GARYTNGAYATHAARATHTTYYTNGCNATHTCNAARGARYTNGTNACNCAYYTNGGNGGN TGYCAYTGYGGNGCNGTNMGNTTYTCNGTNGARGCNCCNGCNCAYYTNGAYGTNGTNCAR TGYAAYTGYAGYGTNTGYYTNAARAARCARAAYCAYCAYTTYATHGTNCCNAARTCNMGN TTYACNYTNYTNCARGGNTCNGAYTTYYTNACNACNTAYACNTTYAAYACNCAYAARGCN AARCAYACNTTYTGYAARACNTGYGGNGTNCARAGYTTYTAYACNCCNMGNTCNAAYCCN GAYGGNTAYGGNGTNATGCCNCAYTGYYTNGARCCNGGNACNGTNAARTCNACNACNGTN TCNACNTTYGARGGNAGYCARTGGGARGARTCNATHAARAAYTCNAAYYTNGCNCARTAY TCNAARAGYCCNTCNTAYGTNGTNTTYACNTAYGGNACNYTNAARMGNGGNGARCCNAAY TAYMGNCARATGGAYAAYCARGARGGNMGNTTYGCNGARTTYYTNGGNTGYGGNGARACN GCNGARAARTAYCCNYTNGTNGTNCAYTCNGCNTAYAAYGTNCCNTTYYTNATGAARGTN GARGGNCARGGNCAYAAYGTNAARGGNGARYTNTAYMGNGTNAAYGARGARATGYTNAAR CAYYTNGAYATHTTYGARTTYCAYCCNCARYTNTAYYTNMGNCARGARGCNACNATHTCN GTNACNGARGAYAARGAYGAYAARGGNATHGTNCCNCCNGARTCNAARAARTGYTGGGTN TAYTTYYTNTCNAARGCNAARGAYGARATGYTNAARYTNAARTAYYTNTCNGARTAYAAR TCNGARTCNAARGARCAYGCNCCNTAYYTNCCNMGNGTNGAYMGN---GAYAGYGCNAGY TTYGARGAYACNMGNTGYAARTGYGTNTGYTCNAARACNAARGAYGCNAGYGGNAARGAR TCNMGNACNGTNTTYMGNAAYACNACNMGNAGYGARCARTGYGAYTGYGARCAYGTNGTN MGNCCNYTNGCNCCNACNYTNTCNTGYTCNYTNTGYCARTGYAARACNGARACNMGNAAY ACNACNACNATHAARGTNGTNGTNATHTTYATHATHTGYGTNGTNTCNYTNYTNTTYGTN TAYATGYTNTTYYTNYTNTGYYTNGAYCCNYTNYTNCARAARMGNCCNGCNAARTCNTAY CARCARCAYACNAAYGARGARCCNCARGARGARGAYYTNTCNCARTCNCARMGNACNGAR GARTCNGCNGGNCCNTCN---------CARGGNCARYTNACNGARTCNYTNTCNGCNMGN CARMGNTCNYTNYTNAAYATHGTNACNAARGARCARAARAARTGGAARGGNACNGTNCAR GARCARMGNMGNAAYATHTAYGAYMGNCAYTCNATGYTNAAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNGGNTTYYTNGGNAGYCARAARGCNYTN ACNACNGCNYTNCARCCNTTYAAYTCNYTNMGNATHCCNGTNTAYCAYYTNATHGGNAAY CAYGARYTNTAYAAYTTYAGYMGNTCNTTYTGYYTNAARTGYCCNYTNAAYAGYGTNYTN ACNACNGAYATHCARTAYGARCCNAAY------------------MGNYTNTAYTAYACN TTYYTNCCNCAYCCNAARYTNMGNGTNGTNYTNYTNGAYTCNTAYGARGTNGGNGTNYTN GGNTAYTCNGAYGAYCCNGARAAYGARAAYTAYAARAARGGNCARGCNATGYTNMGNGAR AAYAAYCCNAAYCCNGGNGARAAYGAYACNACNGGNYTNGARGGNACNACNAARMGNTGG GCNGCNTTYAAYGGNGGNYTNGGNGARAARCARYTNCARTGGYTNTCNCARATHYTNGAR AARGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNATHAAYGTNYTNAAYGAY TGGACNAARMGNTTYGARGCNAAYGGNATHYTNGAYGCNTCNTCNAGYGCNGARTAYATH AGYGCNCAYGTNYTNGGNAARAARACNYTNCAYAAYGTNAAY---ACNGARTAYCARGTN GAYAAYMGNGAYGTNGCNGARATHGCNAAYYTNAGYMGNYTNMGNYTNGARMGNATGCCN GTNCARTAYATHYTNGARGARTGGGAYTTYGAYGAYATGACNYTNAARATGGCNCCNCCN GTNTTYATHCCNMGNCCNGARACNGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------YTNMGNTCNGTNTGYGTN GAYATHYTNCCNGARGCNTGYGCNYTNACNAARMGNAAYGCNGARATHGTNGGNGTNGAR GGNMGNGTNCAYGTNATHAAYGGNGAYTTYACNMGNYTNGCNGTNATHTCNGARYTNYTN CCNYTNGGNCCNTTYTGYYTNYTNGTNAGYAAYCCNCCNTAYGTNACNYTNGAYGARATG AARGAYYTNTCNCCNGARATHAARMGNTAYGARAGYCCNGTNGCNYTNAAYGGNGGNGTN GAYGGNYTNGAYATHGTNMGNCAYATHYTNTAYCARGCNGARAAYYTNYTNATGCCNGAY GGNCAYYTNTTYYTNGARGTNGGNGARAGYCAYCCNGCNATHATHGARAAYTTYGTNAAY AAYCARMGNMGNGAYYTNMGNYTNMGNTTYATHAGYAGYAARAARGAYGTNTAYCARMGN AAYMGNTTYTGYCAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CCNMGNCCNTAYACNACNTTYGARYTNGAYCAR ATHMGNCARCAYGCNMGNAGYYTNGGNATGAGYCCNGARYTNGCNGAYTAYTAYGCNCAR GCNMGNCARTGYGGNGGNCARCAYACNATGACNTAYCCNAAYAARMGNACNACNAARYTN AAYAAYYTNGGNCARGTNATHMGNGARGARGARACNATHYTNCCNYTNTAYAARGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGTTYAARAAR CARAARTCNAARGTNYTNCARAAYGGNAGYMGNGARTCNGTNGAYAGYCARGTNAGYAAY AGY------AGY---GARAAYYTNTCNCCNGGNACNAARGAYGCNAARGAYACNGTNGAY AARATHYTNCAYCARMGNGTNCAYTTYCARGTNTAYTAYYTNGGNYTNGTNCCNGAYATH AAYYTNACNAAYTCNAARAARMGNGAYACNGARGCNCARYTNATHGAYGTNGTNGARGAR AGYCARATHGAYGGNAARYTNCARGTNACNGCNACNGAYGARAAYAARGTNGTNATGAAY ATHTCNMGNCAYGGNATHAARGTNYTNGAYATHGCNGGNAARGARGTNYTNCARMGNCAY CCNYTNCAYACNATHGCNCARYTNACNGARTAYAAYGAYGGNTTYGGNMGNCARAAYATH GCNGTNAARATHGGNCARGTNGGNAARAAYGTNTAYCARTGYTAYGTNTTYCARTGYCAY TCNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARGARCAYGCNGGNTTYYTNGAY CCNATHGARGARGAYMGNATHACNMGNMGNGARAARCARATHGTNTAYGGNAARAGYACN GARTCNTAYAARYTNTAYATHAARACNGTNCCNAARGAYGARMGNTCNGTNGAYMGNMGN AARCAYCCNMGNACNCCNGTNAARAAYGTNMGNYTNAGYMGNMGNAAYTGGGAYGCNCAR ATHAARGCNTGGAARAARCAYGTNCAYCARTGGGCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ACNACN--------------------------------- ------GGNACNAAYAARGCNAGYAGYGGNAGYTCNCCNGAYGAYATHCCNYTNCCNGGN AARGAYGCNTCNTCNTCNGCNTCNACNTCNGCNAGYCCNAARAARGAYGARGARAARTCN GTNYTNACNGAYATHCCNYTNCCNACNACNTCNACNGGNAARCCNGCNGAYGGNAARGAR AAYGCNAAYTCNGARGGNGCNCCNGTNGCNAAYAAYAAYAAYGGNGARGCNGCNGTNGCN GCNACNGTNCCNTCN---------------------------------------GCNGAY CCNCAYTCNGCNGTNAAYCCNTCNAGYGGNGGNGGNGGNGGNAAYCCNATHGGNGAYGGN GGNGARAAYAGYAAYAAYYTNCCNGARGARATGGGNCCNGGNGGNGGNCCNGAYATGYTN GGNTAYGAYCARGARTCNTAYAAYCARATGGGNTAYGGNAAYCAYGAYGCNGCNTTYTGY GARGAYACNGGNTAYGAYAAYTTYGAYTTYGAYGGNAGYGGNGAYTAYGAYCARCARGGN GGNGGNTAYGAYGAYGARCAYCAYGAYTAYGAYTAYAAYCCNGAYCCNTAYCAYCAYCCN CCNYTNMGNCAYCARGGNCCNCCNCAYGGNCAYCAYATGMGNGGNCCNCCNCCNCCNGGN TAYMGNGGNCCNCAYCCNMGNATGTTYCCNCCNGAYATGMGNTTYGGNCCNCCNMGNCCN GGNATGGGNCCNCCNMGNATGMGNCCNCCNAAYGGNCCNATGGGNCCNCAYCAYCCNATG GGNCCNMGNGGNCCNMGNCCNCCNATGGGNCCNGGNGGNCCNATGGGNCCNCCNGGNATG MGNGGNCCNCCNCCNMGNGGNCCNCCNCCNMGNGGNCCNCCNGGNATGMGNGGNCCNCCN GGNATGCCNGGNCCNMGNGGNYTNCCNCCNMGNCCNGGNATGATGGGNCCNCCNCAYGGN GGNCCNATGGGNCCNAAYGGNCCNMGNCCNMGNATGGGN---CCNCCNCCNMGNATGGGN CCNCCN---CCNGGNCARGGN------------CCN------------------------ ---CARGGNCCNATGCCNCCNCARGGNGGNCCNMGNAGYMGN---------ATGCCNCCN CCNGGNCAYATGCARCCNCCNGGNCARMGNCCNGGNATGCCNCCNCAYCARGTNMGNGGN CCN---CCNAAYATGGCNCAYCCNCCNCCNAAYTAYAAYATGCCNCCNCCNTCNTCNTCN GCNGARGGNTCN---------------------AARCCNCCNGAYTCNATGGARCCNCCN CCNYTNCCNCCNCCNAARGCNCCNACNCCNCARCCNCCNCCNCCNCCNAARAARGARGAR GARAARAARGARGARATHAARCCNATGGTNCCNGAYATHCCNCCNGARCARGCNGARCAR TAYMGNAARYTNMGNGARAARGCNCARAARCAYGCNAARAARCARYTNMGNAARGCNGAR CAYCARGCNAARGGNGARCCNGARAGYAGYGAYGAYGAYGAYGAYGARGARATGGCNAAR AARAARGARGAYGCNGCNAARYTNYTNGCNGARCARAARGARATGGARGARGCNGCNYTN YTNGCNGCNCARGGNAGYGARAARGTNGCNGTNGARGAYGGNGGNGCNATHYTNGTNCCN TCNTCNACNACNCCNYTNGCNGTNCARCARCARGCNGTNTAYATHCARCARCARCCNATG GCNGCNGCNGCNGCNGCNGCNCAYTCNCCNTAYGGNATGGTNTCNACNCCNCAYYTNGTN CAYGCNTCNCAYCCNGCNYTNCARGCNGGNCAYCCNCAY---CAYGCNCAYCAYCARGCN YTNGCNGCNGCNGGNCARCCNCARYTNGTNCARYTNCCNAAYGGNCARGTNGCNTAYGCN ACNCCNGCNAARCCNCARCARGTNCCNATGCARGCNGGNGCNCCNGTNATHGCNATGTCN CCNCARGCNYTNGCNGCNGCNTCNCARTCNCARATGCAYCARCARYTNGTNYTNCARTCN GGNGGNGTNCCNGGNCARGTNCARATGGCNCAYGCNGTNCCNGGNGCNCARTAYATGTCN CAYATHATGGCNGCNCARGCNCARGCNCARGCNCARGCNCAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNTTYGGNACNAARTGG CARTTYAGYGGNACNTTYTCNGGNGAYGGNGGNGTNYTNCARMGNGAYAAYTCNGAYGTN ACNYTNGTNGTNGGNMGNGARGCNGTNCCNTCNGGNAGYTAYGTNACNATHCARGGNGCN ATHTTYACNGAYGCNTCNGARATHMGNGGNAARTTYGGNGTNGCNTCNAAYGARATGYTN ATHACNCCNYTNGTNGARTAYCAYGCNGARGAYTCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATGGGNYTNMGNGARYTNTGGAAYATHYTNGARGAY GTNGGNGARGCNAARACNYTNGCNGCNTTYMGNGGNAARAARYTNGCNGTNGAYYTNAGY ATHTGGYTNACNCARTGYAARACNGCNGTNCCNYTNCAYTAYGARMGNGCNYTNTTYTTY AARATHYTNCAYYTNATGMGNCAYGGNATHACNCCNGTNTTYATHYTNGAYAGYGCNGAR GCNATHCARATHAARGAYMGNCARMGNGGNGCNGARTTYTTYAARYTNAGYTCNCARTGG GARGARYTNYTNMGNACNATGGGNTTYCCNGTNATGMGNGCNAGYGGNGARGCNGARAAR GCNTGYGCNCARYTNAAYTCNTAYAARTTYGTNGAYGGNGTNATHACNGAYGAYGGNGAY GCNTTYGCNTAYGGNGCNACNACNGTNYTNAARAAY---TAYAAYGTNAARAAYAARAAR GTNCAYGTNTCNGTNTAYGARATGTCNAAYATHGCNGARAARYTNGGNYTNGGNCARAAR GARATHATHGCNGCNGCNATHYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARACNAGYYTNGARMGNCARMGNACNAGYAARYTNAARCARYTNCAYGAYCAYGCNAAY MGNYTNMGNCAYGARGTNAARYTNYTNGAYYTNGAYMGNCARMGNCAYACNGTNGARGTN MGNAARMGNYTNGARCCNGGNAARGAYTAYAGYTAYGAYGARGTNCARATHCAYAAYACN GARMGNMGNYTNGGNGCNAAYATHGCNTCNTTYTAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGGAR GCNAGYAARYTNTCNMGNYTNMGNGARGARCARYTNAARGCNGTNTCNGARACNGARGAR AARYTNACNCARTTYGARAARTTYAARGGNGAYTAYAARGCNYTNCARAARMGNYTNGAR ACNYTNCCNGAYAARGTNACNCAYGAYGTNATGGTNCCNTTYGGNAARYTNGCNTTYATG CCNGGNCARYTNGTNCAYACNAAYGARATHYTNGTNYTNYTNGGNGAYAAYTGGTTYGCN GARMGNTCNGCNAARCARGCNAGYGARATHACNGAYMGNMGNATHMGNGARYTNGAYAAY MGNATHTCNGARYTNAARAARCARAARAGYYTNYTNGARCCNMGNYTNGGNATGACNTCN GARYTNCARGAYGTNGCNGARGGNATHGGNGAYTAYAARGARATHATHGARGARTAYGAY GARGARAARGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYGGNGGNGARACNTCNTCNAGYAAYGCNACNGTNCCNAARCCNGAR ---GARCCNCARAARMGNTCNGCNATHGGNTCNTTYYTNGTNYTNGCNATHAARCARAGY TAYATHYTNTCNYTNGTNGGNATGATGGCNTGGAGYATHACNTAYCAYTCNTGGYTNACN TTYGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYGTNGTNATHGGNTAYCAYGARGAYGAYYTNGAR TTYGTNAAYAARYTNGCNGGNAARYTNMGNTCNGCNGGNYTNAGYGTNTGGTAYAARAAY CCNGGNGAYGAYGCNAARAARACNAGYGARGCNATHYTNGGNTGYAARATHTAYYTNCCN GTNYTNACNGARYTNTCNGCNGTNGAYAARGGNATHCAYGARCARYTNTCNYTNGCNTAY ATHTCNAAYTCNGCNATHTAYCCNYTNGGNAARATHTGYTTYAAYYTNYTNGCNCCNAAR YTNAAYGGNGGNGCNMGNYTNATGYTNGCNAARATHAAYTGGTCNTTYATHYTNAARGAY TCNCAYTTYGAYGARMGNACNGAYACNATHATHNNNTGYATGAARAARGAYATHCARAAY ATGGAYAARACNTTYGARTCNCCNGGNGAYGAYTCNGGNTAYGTNGTNACNCAYGGNATG MGNATHCCNATHAGYACNTCNCAYYTNCCNAGYTCNGGNAAYGARGARCCNGARTTYYTN ACNTTYTCNMGNGGNATHGAYYTNAGYTCNATHAGYCARGAYACNCCNTTYTGGGAYMGN CAYTTYAARGGNAARAGYGARGTNACNTGGATHGARTAYMGNGAYAARTTYYTNCARGAY TAYGCNGCNAARATHATHGARGGNTTYTCNGAYAAYGCNGARGARMGNAARAARTTYTTY GTNAAYYTNATGTAYAARGAYGTNTTYTCNYTNAGYAARATHGTNAARMGNTCNGTNTAY GAYAARTTYTGYGGNAARCCNCAYCCNCAYGCNTTYTTYACNGGNATGCARGAYTAYGTN ATGGCNTAYGCNTCNYTNMGNGARGTNYTNAGYATGGAYAGYAGYYTNMGNATHCCNACN ATHCARAAYYTNGGNMGNTTYCARTTYCCNGCNATHGTNTCNGGNYTNTCNGAYATGYTN AARGAYGARGAYCCNAAYGTNMGNGCNGTNGCNGCNATHGCNYTNGCNCAYGCNGGNTAY AARATGGCNCCNACNGCNGAYAARATHATHGGNYTNYTNGARGAYGARGAYMGNYTNGTN MGNGARAGYGCNTGYYTNAGYYTNGGNTAYYTNMGNTCNACNMGNGCNGTNACNCAYGTN GTNGAYMGNTGGMGNAAYGAYCCNATHTCNACNGTNMGNGARGCNGCNGARYTNGCNYTN AGYMGNATGGAYGCNCCNGAYGCNGTNCARTGYATGAARGTNACNAARGTNYTNTCNTCN GARATGAAYGCNYTNAARCCNACNGCNTTYAAYYTNGAYYTNAARACNGCNGTNATHCAY GARGGNAARAAYGGNAGYATGTTYGGNTAYTCNGTNGCNCARCAYGTNGAYCARTCNACN CAYTGGYTNYTNATHGGNGCNCCNMGNGCNCARACNMGNCARACNGAYGTNGTNMGNGGN GGNGCNGTNTAYMGNTGYAARACNGAYMGNGTNAAYTCNTGYCARCARGTNCCNTTYGAY ACNAARGGNAAYAAYATHMGNTAYGARCARAAYTCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TTYGCNTCNAGYCCNYTNTCNYTNTCNATHTAYGAYCARGARMGN CCNAGYATGTAY------TGYGGNAGYTCNAARGCNAAYTAYAAYAAYYTNGAYGTNTGY GCNAGYATGGCNGARGARAGYGGNYTNYTNGAYGAYAAYTTYGARGAYAGYTCNYTNAAR AAYATHYTNACNCCNGARATGYTNAGYTCNATGGCNACNTCNTCNTCNGGNTTYACNTCN ACNGAYYTNTGGAGYACNAARGTNACNATGGAYGAYTCNGTN------TCNCARGAYCAR AGYGTNGAYGCNCCNTTYATHCCN---YTNGGNATGGAYTCNGAYATGTTYATH---TCN ACNYTNYTNAAYATHGAYTCNAAYGAYAGY------AARTTYTCNTTYCCNGAYYTNGAR AGYATHATGAGYAAYCCNCCNTCNTCNTGYCAYACNCCNACNCCNYTNTCNTCNGARTCN MGNCCNGARTTYGTNGARCAYCCNACNYTNTCNGGNACNGGNMGNATHAAYTTYGCNTCN MGNAAYAARGARTCNACNACNAAYGTNGCNGAYACNATHATHGGNCARGAYTTYGTNCAR AARAARTTYACNACNATGAARCCNAAYTTYCCNCCNMGNAARTCNGARCCNCCNGTNGGN GTNGTNGCNCCNGTNAARATHYTNGARGAY------------------------------ ---------------MGNAARMGNTTYATGAGYCAYCARCCNGTNAARATGGARGTNACN GAYYTNAAR------------------------TCNAGYAAYGCNAARTCNTGYGCNGTN GAYATGGCNGARYTNTCNCCNCARACNGTNCCNTCNTTYAAYGTNTCNAARCARGARATH GGNTGYAGYCCNATHAARYTNGARCCNAARTCNCCNGARATGAARGCNMGNCARTGYATG AARMGNTCNTCNACNGARGAYAARTGGGARGAYGTNAARCAYTTYATGCAR------GGN GAYGGNACNAARGGNAARMGNMGNMGNTGYGAYTCNGGNAGYTCNGGNATHACNTCNGAR GAYGGNGAYGAYGAYGAYAAYGAYTAYGGNTAYCARAAYGAYTAYGAYAGYGAYGAYGAY ---------GAYYTNGAYGCNGAYYTNGCNCAYATGAARCCNGGNAGYTGYGARTCNYTN ATHGGNGGNGGNAARAARCARAARCARTAYTTYTGGCARTAYAAYGTNCARGCNAARGGN CCNAARGGNACNMGNYTNAARYTNGCNGTNGARTCNCCNACNGAYCCNCAYATHYTNAAY GGNTTYGARGAYCCNGTNTTYGAYGARGGNAAYACNACNGTNGCNGGNATHMGNCAYGGN GGNAARGCNMGNAARGGNGAYGGNAAYGARGTNACNCCNAAYCCNCAYAARYTNTTYAAR ATHGGNCAYCARYTNYTNMGNYTNAAYAARAARATHAAYGCNTGYCARYTNGGNTCNGAY GTNCCNYTNGCNCARMGNAAYGARTCNMGNAARGARAARAAYAARYTNGCNTCNMGNGCN TGYMGNYTNAARAARAARGCNCARCAYGARGCNAAYAARATHAARYTNAAYGGNYTNGAR ATGGARCAYGGNCARATHAAYAAYGTNYTNMGNYTNYTNTGGCCNGARYTNMGNGARMGN GCNAARMGNYTN------CARAAYGAYGAYCAYCAYGTNGAYGTNAARCCNGARCCNGAR AAYAAYYTNTTYAAYAARYTNACNGGNTAYATHAGYTCNAAYYTNAARACNATGGTNGCN GCNCAYACNACNGAYTAYGTNAAYGAYGTNATHATGACNGTNGARAARGGNGAYYTNTCN GGNGGNYTNAAYATHMGN---------------TCNMGNMGNTCNTCNACNCCNAAYTCN GTNATHAARAARGARAAYATHCCN---------MGNMGNMGNTCNACNGTNATHAGYGTN AGYGAYGARGGNACNGCNGTNGGNMGNGARYTNGARCCNGCNYTNGCNTAYAARGTNGAR ACNGTNMGNMGNTCNGCNMGNGCNTCNMGNATHYTNAAYGARYTNGTNATHGARAARGTN GAYGGNGARAARAGYTTYNNNGARGTNTCNTTYGARAGYAGYMGNAAYAAYTCNATGAAY ATHCARAARTCNAARTGYAAYACNCCNYTNGGNYTNCARTCNAAYACNACNTCNCCNTTY ACNCCNMGNAARTCNAAYGARGTNACNGTNTCNAGYGGNAAYAAYTCNTCNAAY------ ---ATHACNACNCCNACNAGYGCNYTNMGNGCNMGNCAYTCNATGGCNATHTCNTCNTCN GGNTTYAARGARCCNGGNYTNCCNYTNTCNGCNYTNMGNCARCCNGGNTCNCAYCARMGN MGNMGNACNTGYACNCCNAARTCNAARACNCCNGARCAYATGATHGGNATHYTNAARAAR AGYCCNATGGTNGARATGTCNMGNMGNMGNTCNMGNCAYGTNTCNTCNCCNGGN---GCN CCNAARGGNCARTAYTTYMGNGAYYTNATHTCNAAYGARACNGARMGNYTNGCNAAYYTN TCNCARAARTGGAAYGCNGTNGCNTCNMGNGARGTNGGNYTNCARGARGARGTNYTNGGN CARATHMGNTCNACNGTNGGNAARGCNYTNYTNYTNATHGARCARMGNTTYAARCARTTY TCNGGNYTNGTNGAYAAYTAYGCNTTYGAYYTNGGNGARAARAARACNACNCCNACNGAY YTNCARGGNTTYTGGGAYATGATHTAYTTYCARGTNGARGAYGTNAAYAAYCARTTYAAR GARYTNGAYGARYTNCARCARTCNGGNTGGCARGTNAARMGNAAYACNCCNAARGCNGCN AGYYTNCARYTNAARAARAARGTNATHAARGGNAARCCNAARGCNAARGGNGTN------ ------AARTCNAAYTTYGCNGCNTTYMGNGCNGARYTNCARAARAARAARGCNGCNCAR GCNACN------------GARGARYTNAARAARATGAARGTNCCNGARYTNAARCARGCN YTNAARGAYAARGGNYTNTCNACNACNGGNACNAARCCNGAYYTNATHAARMGNYTNGTN GARTCNGTNGGNGCNGCNGGNGAY---GGNGCNGAYCCNGTNATHGAYGAR--------- ------GAYGARATHYTNAARGAYGAYTCNACNCCN------------------------ ------GTNGCNGCNGCNGTNCCNCCNGARCCNGCNGCNGTN---------TCNTCNACN GARAARTCNGARACNGCNAGYAAYGGNGTNGTNCCNACNAGYCCNCARCCNACNCAR--- ------ATGGCNGCNGAYACNACNGTNTCNGCNAARCCNGCNGARGTNAGYAARYTNACN GARGCNGARMGNYTNAARATGMGNGCNGAYAARTTYGGNGCNACNTCNGARAARGCNAAR AARNNNYTNMGNGCNCARMGNTTYGGNATHGCNYTNAGYGARAAYAARTCNGGNAAYATH AGYTCNTCNACNGARCCNGTNGAYGTNGARAARYTNAARAARMGNGCNGARMGNTTYGGN GTN------------TCNACNAGYTCNGTNACNGARGAYGARAARAARMGNAARMGNGCN GARMGNTTYGGNTCNAGYACNGCNACNTCNTCNACNTCNAARAGYGTNAGYYTNAAYTCN ACNGAYAGYGARYTNGARGCNAARAARMGNAARMGNGCNGARMGNTTYGGNYTNACN--- GTNGARTGYAARTGGMGNGGNTGYGCNYTNGAYCCNAGYGAYYTNYTNGARCAYGTNMGN AARCAYGCNGAYACNCARATHACNAARAARAARTAYGCNTGYYTNTGGACNGAYTGYAAR GTNTAYAAYCARCCNTCNYTNTCNGGNTCNTGGYTNGARMGNCAYGTNGTNTGYCAYAGY GGNCARMGNCCNTTYAARTGYATHGTNCCNAARTGYGGNCARMGNTTYCAYTCNCARGTN ACNYTNGARMGNCAYGTNAAYGGNCAYTTYGCNTCNACNGCNGCNAAYGGNTCNMGNCCN GGNMGNAGYMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GCNTCNGGNGTNACNATGCARGCNGAYGTNYTNYTNGAYAARATHTTYAAYACNYTNCCN GCNYTNGGNACNAAYCAYTCNGAYMGNYTNGTNGAYATGMGNGAYYTNTGYCAYTGYTTY AAYAAYAARTCNAGYCARAAYATGATHYTNCCNGGNTGYYTNGCNCCNCCNMGNYTNAAR GAYTCNGCNACNCAYYTNACNGCNACNGTNATGAARAARCAYAARGARGCNYTNATGGAY ATHAAYMGNMGNYTNGTNGARACNGCNACNTCNGARAARYTNCCNYTNGAYYTNTCNMGN MGNCCNAGYMGNGTNACNGCNGAYYTNYTNGAYTCNACNYTNGCNYTNTTYAARGGNAAR TAYGCNYTNATHMGNAARCAYYTNGAYACNYTNCARGTNGGNATGGCNACNTGYCARACN YTNAARCAYCCNTCNGCNGCNCAYCAYGAYAGYGTNATHGCNAARGARAARAAYYTNYTN CARGCNATHGCN------------------------GAYGGNGARGGNGARAAYGARGAR AAYGTNTAYCCNTCNGCNTTYGCNYTNYTNTCNAARYTNATGGTNACNGARYTNGARAAR GAYMGNGARAAYMGNGARTTYACNYTNGAYGAYATHYTNCAYYTNYTNGTNTAYATHTAY TCNGTNTCNGAYGGNAGYAGYGARAAYCARGARGARGTNAARGTNYTNCARGAYCAYYTN GTNCARGGNGTNATHAARGAYAARGAYTGYYTNCCNCCNATHATGAARGTNATHGTNGGN GAYAARGTNACNGARTCNATHYTNCCNGAYCARATHGARAGYATGTGGGARAARYTNGAY GCNGTNATGGARGCNMGNMGNGAYYTNAARGARTTYGGNAAYGTNYTNAAYCCNGGNGGN GAYATGAGYCCNGCNTCNGTNAAYTCNYTNYTNMGNCARGTNATGGARAARATHYTNGAY CCNGCNAARCCNGARATGCCNGAYGTNGARTGYAARTCNGGNGGNYTNAARGAYYTNYTN AARTCNGGNTTYGGNTTYTTYAARAGYTCNGCNAARCCNMGNCCNGGNGAYGCNCCNYTN YTNATGATHATGGTNATHGGNGGNATHACNGGNTCNGARGTNAARATGATHAARGAYATG GTNAGYAGYGCNAARCCNGGNTTYGARGTNATHGTNGGNGGNACNMGNATHAAYAGYACN GARTCNACNYTNAARTCNYTNYTNGTNGAYGAYAAYATHAAYATH---ATGYTNAARGCN GCNYTNAARACNAGYGAYTGGATHAARYTNGAYACNTGGGARTGYGARCARAGYTCNTGG YTNGARACNATHAARGTNYTNMGNCAYATHAARCARCARGTNGAYAAYCARTAYYTNTCN AAYGTNMGNCCNTCNCCNAARMGNMGNAARAARCARCAR---GTNTCNGAYYTNACNCAR AAYAARYTNCCNAARGTNGARGTNGARGAYGARCARGTNCCNYTNGTNMGNTTYYTNTGY GGNGCNGAYYTNYTNGARTCNTTYTCNGTNCCNGGNYTNTGGAARGAYGARGAYGTNGAR AAYATHGTNAARAAYCAYGGNYTNGTNGTNATHAAYMGNGARGGNTCNAAYGCNGAYAAR TTYATHTAYGARTCNGAYGTNYTNACNAARTAYMGNGARAAYATHGTNYTNGTNAAYGAR TGGYTNAGYYTNGAYATHAGYTCNACNAARATHMGNMGNGCNTGYMGNMGNGGNGARAGY YTNAARTAYGTNGTNCARGAYACNGTNATHGAYTAYATHCARGARCARMGNYTNTAYGGN YTNCCNGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNTTYACNGCNATGGARTGYMGNAAYYTN ATGAARGARAARTCNTAYGCNATGGCNATGCARAARYTNCAYGCNGTNYTNACNYTNTGY YTNGAYTCNYTNCAYAARTGYMGNYTNYTNTGYYTNTTYGCNGAYTGYTAYTTYCAYATG GGNTGYCCNCARYTNTCNATHCARACNTAYMGNGAYGCNYTNCARACNAAYTCNACNCAY TAYCCNGTNYTNTAYCARYTNTCNYTNGTNTAYCARAGYYTNGAYYTNCCNGARYTNGAR YTNGARTCNYTNAAYYTNTGYGTNATGGCNYTNGCNGAYGTNGARAARMGNAARAARGAY ---AARTTYCCNGTNATGGAYGTNGAYGARYTNGTNTGGTCNGTNGCNCCNCCNGTNACN CCNGTNTCNTAYATHMGNGTNAARGTNACNTTYGCNMGNMGNTGYYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYTGYGTNGAYCAYGTN TGGGGNACNAGYACNCAYGCNCAYCCNGAYYTNTGYCAYAARTAYATHGARTGYTCNAAY GGNYTNGCNTAYGTNATGGAYTGYCCNGCNGGNYTNGCNTTYAAYGAYGCNATHGAYACN TGYGAYGAYGCNGGNAARGTN---------AAYTGYGGNACNGCNATHACNACNGGNGAY GTNAAYGAYATHTGYMGNGAYCARAAYYTNCCNAAYGGNCCNCAYGCNCAYCCNTTYGAR TGYCAYAARTAYATHGARTGYTCNAAYAARYTNACNACNGTNACNGAYTGYCCNATHGGN CARGTNTAYAAYGARAAYYTNAARACNTGY---GCNGTNGCNCCNTAYTGYAARACNTCN ATHGTNGGNGGNAARACN------ACNGCNTCNCCNACNAAYGARGGNACNGTNTGYACN GAYTAYAAYYTNGCNGCNGGNATHCAYCCNCAYCCNTAYMGNTGYGAYMGNTTYATHGAR TGYAGYAAYGGNCARTCNTAYACNYTNGCNTGYCCNGAYGGNYTNCAYTAYCAYATHGTN GARAARACNTGYGAYGAYCCNCAYAARGTNGAYTGYCARGAYAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GTNAARATHGAYGGN ATHGARGARACNCAYYTNATHGGNCARGTNAAYYTNCCNMGNYTNMGNAGYGARGARGAY TCNCARTGYTCNAARATGGGNMGNTGYTCNTAYCAYGTNACNGTNYTNGAYYTNCARCAR ATHGTNTGYMGNYTNTGYMGNATHGAYGAYTGGMGNYTNYTNTGGTCNGAYAGYGAYAAR TTYATHAAYCARTTYAARTCNTCNAAYTTYTCNYTNTGYTTYCAYCCNTTYAGYYTNTAY CCNATGAARTTYGTNCAYGAYYTNAGYTTYTGGGARCARAAYTCNTCN---GCNACNTTY GAYGARYTNGCNYTNTGYGAYACNATHMGNTGYGTNGCNGGNGAYYTNGTNACNAAYGTN TCNYTNATHGAYGTNTAYGARGAYACNGARTCNAARMGNAARAGYMGNTGYTAYMGNYTN CAYTTYYTNTCNTCNGAYAARTGYYTNCCNTAYGTNACNTCNTGGAARATGCARAGYAAR ATHMGNATGGARGTNGCNMGNAGYYTNGGNGTNCARYTNMGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TAYGTNGTNTGYGTNTGGTGYTTYATGACNTGGAARTGGGGN TTYYTNYTNYTNATHTAYTCNMGNTCNTAYYTNMGNGTNTAYATGAGYCARTCNGAYCCN ACNTCNTAYTCNGARCCNGARAARTGYATGATGAARCARYTNGAYTGGAAYGTNAARYTN GAYTTYAARACNCARACNATHAGYGGNGTNGCNAGYYTNTCNTTYGARAARAARCARGAY GARYTNGAYYTNYTNYTNYTNGAYATHMGNGAYYTNAARATHGAYAGYGTNAARYTNCAR GARAAYAAYAARGAYYTNACNTTYACNGTNGAYAAYCCNGCNAARGTNGAYTAYGGNTCN MGNYTNTGYATHCARYTNCCNGTNACNCARAGYAARAGYTTYACNYTNGAYATHACNTAY AGYACNTCNAARGARTCNACNGCNYTNTGYTGGATGACNCCNGARCARACNGCNGGNAAR MGNCARCCNTAYYTNTAYAGYCARTGYCARGCNATHCAYGCNMGNAGYYTNTAYCCNTGY CARGAYACNCCNGCNGTNAARTTYCCNTAYAAYGCNCARGTNGARGCNCCNAAYGARATH ACNGTNYTNATGAGYGCNAAYMGNGGNGARGTNAARCCN------GGNTCNAARGGNCAY AGYGTNACNAGYTTYTCNYTNAARATHCCNATHCCNAGYTAYYTNYTNGCNATHGTNGCN GGNGAYYTNGARTCNMGNGAYATHGGNCCNMGNTCNAARGTNTGGTCNGARAARGARYTN GTNGARCARGGNGCNTAYGARTTYGCNGARACNGARTCNATGYTNCARGTNGCNGARGAY YTNATGGGNCCNTAYGAYTGGGGNCARTAYGAYYTNYTNGTNYTNCCNCCNTCNTTYCCN TAYGGNGGNATGGARAAYCCNTGYYTNACNTTYGTNACNCCNACNYTNYTNGCNGGNGAY MGNTCNYTNGTNAGYGTNGTNGCNCAYGARATHTCNCAYAGYTGGACNGGNAAYYTNGTN ACNAAYGCNAAYTTYGARCAYTTYTGGYTNAAYGARGGNCAYACNGTNTTYYTNGARMGN AARATHCAYGGNMGNYTNTAYGGNGARGCN---TGGAARCARYTNCAYGCNAAYGCNGGN TGGACNGGNYTNAARGAYACNATHAARGAYYTNACNGARGAYGGNCAYGCNCCNTAYACN MGNYTNGTNCCNGAYYTNTGYGGNGTNGAYCCNGAYGARGCNTTYTCNAARGTNCCNTAY GARAARGGNTAYGCNYTNYTNGARCAYYTNGARMGNYTNYTNGGNGGNCCNGAYGTNTTY AAYGTNTTYYTNMGNGCNTAYATHGARMGNTTYAARTTYCARGCNATHYTNACNAARGAY TGGAARGAYTTYYTNTTYGGNTAYTTYTCNTCNACNGARGAYCARAARAARYTNAAYAGY GTNGAYTGGGAYAARTGGYTNTAYGGNGARGGNGTNCCNCCNTTYGARGCNGAYTAYGAY YTNAGYYTNGCNCARGCNAGYCAYGAYYTNAGYAARMGNTGGACNAAYGCN------AGY GGNGARGAYTCNTTYTCNCCNGGNGAYATHAARGAYATGAGYAGYGAYGTNGTNMGNGAY TTYYTNYTNAARYTNCAR------GARGCNAARYTNGCNYTNTCNAARGTNCARAARYTN GARTCNGTNTAYCAYTTYCAYGCNGTNAARAAYTCNGARATHMGNYTNGTNTGGYTNCAR YTNTGYATHCARGCNCARTGGGCNGAYGCNATHCCNCAYGTNYTNAGYTTYYTNAAYGAR CARGGNMGNATGAARTTYGTNATHCCNYTNTAYAARTCNATGAGYAARTGGGARGCNGGN MGNAARCCNGCNCAYGAYAAYTTYYTNAARCAYAARGAYGARATGCAYACNACNACNATG AARAARGTNGAR------------------------------------------------ ---------------------------------------------------TCNCCNAAR TCNCARCARYTNAAYGAYAARMGNGTNMGNMGNGARATHGCNAAYGGNAAYGARMGNMGN MGNATGCARTGYATHAAYGCNGGNTTYACNTCNYTNMGNGCNYTNATHCCNCAYYTNGAR GGNGARAARYTNAGYAARGCNGCNATHYTNCARCARAGYATHGAYTAYATHAGYGGNATG GARAARGAYAARAAYMGNATHCARATGCARYTNGARMGNACNACNMGNYTNYTNGCNGAR YTNGGNCARCARGAYMGNATGATHGTNGARTCNTAYGTNACNAAYACNCCNCCNCCNACN AARMGNAARAARMGNGAYACNGARTCNTCNGAYGARGGNGTNGGNTCNYTNTCNGAYGGN TCNGAYGAYTGYGGNACNGAYYTNMGNCARAARAAYGARGCNYTNMGNCAYCARATGGAY MGNGARAARAARMGNGGNGAYTCNYTNGARGARGARAAYAAYAGYYTNMGNAAYYTNATH TTY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGAYAAYCAYGAR GARATHYTNGAYGCNYTNACNGTNTTYGGNAARAAYCCNAAYCCNCARGARATHCCNACN GTNYTNGARCARTAYYTNAAYTCNGTNGCNAARAAYGGNGARACNYTNTTYCCNTGGTCN CARYTNAARCCNYTNATHYTNMGNAARATGGARYTNGTNATHATGGARYTNMGNMGNAAY YTNGCNTCNGARAAYATHCCNACNMGNCCNAAYGTNGARAAYGTNMGNTTYGAYGTNATH CAYGCNMGNATHATHGAYTCNYTNCAYAARTTYAAYGGNGCNCCNTTYACNATHCARMGN YTNTGYGARYTNYTNACNGAYCCNAARMGNCAYTAYAARMGNAGYGAYAARTTYATGMGN GGNYTNGARAARAAYGTNYTNGTNGTNAGYACNGTNGAYCCNTTYGGNMGNAARGTNGTN TCNGARYTNGGNAAYAARCCNGTNYTNAAYGGNATHYTN---GAYATHAAYGGNTCN--- TTYCCNCCNMGNGAYTCNGCNYTNAGYGTNCCNYTNCCNCCNGTNCCNGGNTGGGTNAAY ACNGCNGCNGTNAAYMGNAAYGTNACNACNGGNTCNACNACNATGCARTCNGCNYTNYTN GAYAARACNGGNTCNACNYTNGAYAARGAYTCNGAYGGNGTNGTNTCNAAYAGYATGGCN GGNTCN---GGN------ACNCARGTNTTYTCNGAYCARGGNGAY---CCNYTNGCNGTN CARTCNGARGARGTNGTNGARGARACNGTNGTNACNATGGAYACNGGNGARGTNACNTCN GTNGTNACNGAYGGNGGNGARTCNYTNGCNGARMGNGARATHGARGCNGAY------ATH GGNGARGAYMGNGAYGCNTCNTCNTCNTCNTCNTCNTCNTCNTCNTCNTCNGARGARYTN TCNACNTCNTCNGAYTCNGARAAYGGNGCNTCNCCNYTNGAYATGGCNGCNAAYAAYYTN AAYGARGARGAYACNGARAAYMGNCCNTGGGCNGCNTTYGCNCARGAYTCNTCNAAYCAR CCNYTNGCNGARGARAAYCARACNTCNGGNGTNTCN------TCNTCNTCNCCNCAYAAY ACNTCNACNGCNGAYACNCCNTCNTCNTCNTCNYTNTCNTCNTCNTCNTCNCCNGCNTCN TCNGARACNCARTCNTCNYTNYTNTCNACNTCNACNACNATHACNTCNAARGTNGARGAR GAYCARCARCARGARGAYGAYAGYCCNATHGCNTGYGTNGCNAAYCARCARACNACNACN CCNTCNGAYCAR---------------------------------------TCNTGYGAY GARTCNTCNACNGCNGAYAGYAAYCARAGYYTNGGNTTYGAYCCNATHGTNACNTCNCCN CARCAYACNAAYGARATGACNACNGCNACN---------------------------GTN ACNGAYAARYTNATHTCNTCNTCNACNAGYACNGTNATHCCNACNACNACNTCNACNACN AAYACNAGYTAYAAYACNTCNTCNGAYGTNCAYACNTCNTCNTCNTCN------------ ---------TCNTCNGCNTCNGCNAGYGAYGGNGTNGCNGCNCCNCARCCNCCN------ ------------ACNTAYGCNCARGTNGTNGCNTCNTCNACNTCNTCNCCNCCNTCNATH CARCAYATHTCNCCNTAYGAYTCNGTNGCNGARCCNGTNCCNGCNTGYGAYAGYGTNGCN GGNYTNGARMGNYTNGTNGGNTCNGTNGARCARTCNYTNTCNTCNTCNTCNTCNTCNTCN ATHGTNTGY------CCNTCNTCNTCNTCNACNTCNTCNTCNTCNCCNTCNTCNTCNCAY CCNTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AGYATHAGYAAYYTNGGNCARYTNTCNTCNAAYYTNAAYYTNCARGGN YTNGCNGGNYTNTCNGGNGTNAAYATHGCNAAYYTNAGYGGNYTNCARCARATGCARGTN TCNYTNGCNCARATHGCNGTNCCNATHACNATGATHAAYGCNAAYGCNAAYYTNYTNCAR GGNCARACNGGNATHYTNGCNAAYAGYTCNTCNTCNACNGGNAGYTCNACNGCNACNYTN GTNCCNATGGTNACNGCNTTYCCNGCNTCNTCNACNAAYACNACNACNACNACNTCNGTN ACNGGNTCNTCNCARGTNGCNGTNTCNACNGGNTCNAAYATGYTNTCNTTYCCNGTNGGN YTNAGYGGNYTNACNCARYTNATGCCNGTNACNTCNAARGGNCARGGNGGNCARACNATH MGNCCNACNGCNATGCCNYTNYTNCARYTNCARGGNCARCARGGNATHCARYTNYTNAGY YTNCARCARMGNGGNGGNGTNAAR------ACNAGYAGYTCNAAYACNGCNCARGGNATH ACNMGNYTNGCNCARGCNGGNACNACNACNGTNCCNYTNTCNACNGTNYTNGCNGGNCCN CARATGACNGCNYTNGGNATGGGNAGYAARCCNGGNCARGGNGGNAGYACNGCNATHACN GCNCARCARYTNATHCARYTNACNGGNGGNCARCARGCNGCNGCNGGNGGNGGNAAYCAR CARMGNGCNACNCAYATHACNTTYGGNAARGGNCARCARGGNYTNCARTTYCAYTCNGTN CARYTNAARCARGCNGGNGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AGYCCNAAYTCNACNTCNGAYAARCCNAGYGGNMGNAARGAYAGYGGNAGY--- ---GGNAGYCARTCNGAYAARCARGARCARAGYCCNAARTCNAGYMGNGARAAYACNCCN GARAARAARAGYTCN------------CCNMGNGAYAARGARAARACNCCNGARAARGGN AGYAARAARACNAARGTNTCNGARTCNCCNGARGARCCNCARCCNTCNACNTCNGCNTCN ACNTCNAARGARGTNCCNTCNACNTCNTCNGCNCCNCCNCAR------AARAARMGNAGY GCNGARTCNGARGARGARYTNMGNCARGCNATHAARMGNTAYMGNMGNCARGAYGARGAY MGNATGAARATGCARGTNYTNGTNTCNAAYTTYTCNGARGARCARYTNAAYMGNTAYGAR ATGTAYMGNMGNGCNACNTTYCCNMGNGCNTCNATHAARMGNYTNATGCARAAYATHACN GGNTCNGCNGTNTCNCARAAYGTNGTNATHGCNATGTCNGGNATHGCNAARGTNTTYGTN GGNGARGTNYTNGARACNTCNYTNGAYGTNAGYGARAARTGGGGNGAYACNGGNCCNYTN CAYCCNAARCAYYTNMGNGARGCNGTNMGNATHYTNAAYTCNAARGGNATGATGCCNTCN ACNAARACNAARAARTCNATGTTY---------ATGGCNGCNAARMGNGTNGAYATHCCN AGYGARAAYAARYTNGGNACNGTNCCNGCNATGATGGCNGGNGAYCCNACNACNATGAAR CARGGNYTNATHGTNYTNCARGARTGGTGGGGNATGAAYGAYCARATHCARGAYTGYGGN AARGAYYTNTGY---GGNCARGGNAARATHGTNACNYTNGTNCCNGAYYTNTAYMGNGGN AARGTNACNACNGAYAAYGARGARGCNGGNCAYTTYATGGGNGAYYTNGAYTGGMGNGGN GCNGTNAGYGAYATHCARGGNTGYGCNAARTTYYTNAARAGYCARGGNGTNYTNAARGTN GCNGTNACNGGNTTYTGYATGGGNGGNGCNYTNTCNATGGCNGGNGCNGCNYTNGTNCCN GARATHGAYGCNGCNGTNCCNTTYTAYGGNATHCCNTCNGCNCARYTNTGYGAYGTNACN TCNATHAARGTNCCNATGCARTGYCAYTTYGCNAAYAAYGAYCARACNGCNGGNTTYGCN TCNCCNGCNGARTGGAARCCNYTNAARAARAARYTNGARGARAARYTNGAYATGYTNGAR TTYTAYGARTAYGARGCNGGNCAYGCNTTYACNAAYAARACNGGNGAYAAYTAYAAYAAR AARYTNTGYGAYYTNGCNTTYTCNMGNATGTTYATHTTYYTNGARAARCAYYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AAYCCN GCNGARAARAAYCARCCNCCNYTNACNCCNACNYTNYTNGAYACNAGYAARCCNGARGAR ------CCNAARAARTCNYTNGAYATHCCNCCNGTNGAYTTYGAYTGGGGNTCNAGYGGN YTNACNAAYCCNYTNAARGTNTTYAARAAYGAYAGYTTYAAYAAYGGNYTNTCNGCNYTN GARCCNTTYTCNGAYGTNYTNAARAAYATHGARCCNACNAARGAR---YTNAGYAGYGAR GCNAARAGYATHYTNTCNAARATHCCNAAYYTNAAYTTYATG------------------ ---------------------TGGAGYTCNGTNGCNGTNYTNATHAGYAARGCNTCNACN AGYGAYATHAGYAAYGTNTGYCAYYTNATHGCNGAYAGYTTYTGYCARGAYAARGCNATH AARTCNGAYCARYTNATHTCNTCNTGGTCNYTNGARGARTGGTGGGAYGTNMGNGGNGCN YTNATHGARYTNATHAARAARGCNGTNCARCARGAYATGACNMGNGARCARATHCAYAAY GARYTNACNTCNGTNGAYGAYGCNTAYAARACNATHATHTCNGARGCNATHTCNGTNCAY MGNGGNGCNYTNAARMGNAARYTNYTNCARAAYACNGCNTCNATHTCNCAYGCNGTNYTN TCNGAYTTYGAYTGGAARYTNCARYTNGCNYTNTCNAGYGAYAARATGTCNAGYYTNCAY CARCCNYTNYTNACNYTNGAYYTNGAYATHMGNCAYGCNAAYGGNGAYMGNAARGARGTN GCNYTNGARATGAGYAARGAYGARYTNGCNMGNYTNATHACNTCNYTNGARAGYTGYAGY AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNTGGGGNCAYGGNGGNCAYCAYGARGGNGCNCCNYTNAARTTYTCNGCNGAR ATHCAYAAYAARGAYCAYATHATHGARCAYYTNCARMGNCARATHGCNACNAARCCNAAR GAYCARATGTCNGAYGARGARYTNGARTTYCAYTAYTTYAARYTNCAYGAYTAYGAYAAY AAYAAYAARYTNGAYGGNGTNGARATHGGNAARGCNYTNACNCAYTTYCAYGAYGARGAY GCNGAYAGYGCNAARAARGAY---------------------CCNCCNAARGTNTTYGCN GAYGAYGARATHTCNAAYATHGTNGAYTCNGTNATHGAYGARAAYGAYACNAAYAARGAY GGNTAYATHGARTAY--------------------------------------------- ------------------------------ATGGGNAARGCNMGNTCNAGYGGNTCNGAY GAYTCNTAYTCNMGNTCNTCNMGNAARAARAARAARGARMGNMGNMGNMGNTCNMGNACN MGNTCNAAYAGYTCNAGYMGNGGNGGNACNAGYMGNAARTCNAARAARAGYAGYAGYAAR CAYTCNTCNAGYMGNMGNTCNCCNGCN---AGYCCNGAYMGNCAYMGNGGNGGNGGNGGN CAYTCNMGNMGNTCNMGNTCNMGNTCNGCNGAYMGNMGNACNTCNMGNMGNTCNMGNTCN AARTCNMGNTCNCCNTCNCAYMGNAGYMGNMGNMGNTCNMGNTCNGCNTCNGGNTCNMGN AAYTAYAAYTAYAGY---AGYAGYAGYMGNMGNTCNMGNTCNGGNTCNMGNGGNCAYACN AGY------------MGNMGNTCNMGNTCNGAYTCNMGNGGNCCNAGYGGNAGYMGNTCN TCNAARGGNGAYAGYMGNMGNTCNMGNTCNAARTCNAAYTCNMGNGGNACNACNGAYMGN TCNMGNCAYGGNAGYCCNGAYAARCARAARTCNGARCAYTCNMGNGGNGGNATGACNTCN CARGARAARGTNGARYTNMGNATGMGNAARGCNYTNCARGCNGCNGCNGCNGCNGAYGAR MGNYTNAARAAYYTNMGNGAYCARGAYTCNCCNTCNMGNATGTCNTCNTCNTCNCCNYTN TCNYTNTCNTCNTCNGCNYTNGCNATGACNGCNACNAARGAYTTYGCNGAYTCNGTNGCN GCNATHGAYTCNGGNMGNTTYGTNCARTCNTCNTTYAARTCNGGNGGNATHGTNTGYAAR GAYGARGCNCCNGAYCCN---YTNATGTCNAGYCAYGAYGAYGCNATHTTYGGNTCNYTN TCNTCNATGGGNTTYACNATHAARCCNGAYYTNGAYYTNAARCCNGTNGCNYTNGAYGCN GAYTCNATHATGCAYCCNMGNYTNTTYTGYAAYGCNGARGAYAARATGGARCARTGGATH GAYMGNYTNGCNCARYTNMGNAARMGNAARATHGARGGNGARGCNATG------------ ------------------------------------------------------------ ---------------------------------TTYGGNGGNAARGGNGCNAAYCARTGY ATHACNGCNGTNAAYYTNGGNGCNCARGTNGCNATGGTNGGNAARYTNGGNGAYGAYACN TTYGGNAARGARTAYATGATGAAYATGCARACNAAYAAYGTNAAYTGYGAYCAYYTNAAY ATHGTNCCNGGNGTNTCNAAYGGNGTNGCNTCNATHCARGTNGCNGAYAAYGGNGCNAAY TGYATHGTNATHGTNCCNGGNGCNAAYAAYCAYYTNACNGARGARGAYGTNAAYAAYGCN GARAAYACNATHAARAAYTGYCARGTNYTNATHTGYCARAAYGARGTNCCNCARGAYATH TCNYTNTCNGCNGTNMGNATHGCNAARAARCAYAAYGTNAARGTNATHTAYAAYCCNGCN CCNGCNTCNTCNAGYYTNYTNCCNGARYTNTTYTCNYTNCCNGAYTAYTTYTGYCCNAAY GARACNGARGTNGARATHYTNACNGGNACNACNGTNAARTCNATHGARGAYGCNTTYGAR GCNTGYAARACNYTNCARAGYACNAARGGNTGYAARTCNGTNATHATHACNYTNGGNGAR AARGGNGCNGTNTTYAARGAYGCNTCNTCNAAYGARGTNGTNCAYGTNACNACNTCNCCN GTNAARGCNGTNGAYACNACNATGTCNTTYCCNGGNMGNACNCCNATGGCNATGCCNGGN GGNATGCCNGGNATGCCNCCNMGNATGATGACNACNCCNGGNTAYGCNTTYACNTCNATG GGNATGACNMGNATGAAYCCNATGATGCCNATGCARATGGGNATGATGACNCCNATGATG CARCCNATGATG---CARCCNCARATGCARATGCARCCNCARCARCARCAYATGAARCAR AAYCCNAARTTYGTNCCNCARGARATHCCNAARAGYGAYCCNAARGGNGARAARCCNCCN GTNACNACNGTNTTYGTNGGNAAYATHAGYGAYMGNGCNCCNGAYATGATGATHAARCAR ATGYTNCARMGNTGYGGNAAYGTNYTNAGYTGGAARMGNGTNCARGGNGCNTCNGGNAAR YTNCARGCNTTYGGNTTYTGYGARTAYGARGAYCCNGARGCNACNYTNMGNTGYATHMGN YTNYTNAAYGAYTGGCCNATHTCNAAYAARAAYYTNGTNGTNAARGTNGAYGCNAARACN AARACNYTNYTNGAYGAYTAYMGNAARAARAARCARGGNAGYGAR---GARGGNGCNAAR AARGAYACNGAYTCNAGYGAYAARGAYAARAGYGARGAR---GARAAYGGNGARGTNAAR GAYGAYTCNGARGCNGGNAARGARGAYTCNGARGAYAARGARGGNGAYYTNGAYGARAAY ACNMGNMGNGARGAYMGNYTNGCNCARGCNGGNYTNGARGCNATHATGAARGARTAYGCN TTYGARYTNGCNAARGARCCNGCNAARACNTCNGAYGGNGGNGAYCARGAYAARGARAAR CARATGCCNAARAARGAYAARGARATHTAYATGCAYGCNAARGAYACNGGNTTYGAYGAY ATGGARATGGARGAYGARAARMGNCARATHATHAAYMGNGARATHAAYAARTTYMGNGAY MGNCAYAARGAYGCNGAYGARGARAARGARAARGAYAAYMGNGARAARGARMGNAGYYTN GCNMGNGARMGNGAYMGNMGNCARGARGARAARMGNCAYMGNGARMGNYTNGARAARATG MGNGARCARMGNGARMGN---------MGN---------------------CCNTCNACN ACNMGNGTNTCNMGNTCNAARTCNMGNTCNGCNTCNCCNGTNCCNTCNMGNTCNMGNMGN MGNTCNMGNTCN------------MGNGARMGNACNAGYMGNGAYMGNTCNMGNGARMGN MGNAARGARMGNGARATHGARGARGARGARGARYTNTAYGARMGNMGNAARYTNGARAAR AARYTNMGNGARAARGARGCNGCNTAYCARGARMGNYTNAARAAYTGGGARGGNMGNGAR MGNAARAARACNMGNGARTAYGARAARGARAAYGAYMGNGARGARGARMGNAARGTNGAR GARGGNMGNGARGCNMGNMGNYTNAARGARTTYYTNGARGAYTAYGAYGAYYTNMGNGAY GAYCCNAARTTYTAYAARGGNAGYGCNYTNCARMGNMGNCARAARGARMGNGARAARGAR AARGARYTNGAYAAYMGNGAYMGNCARMGNGARAARGARGARTTYGARGARATHAARMGN AARYTNTTYGAYGARGGNCAYCCNGAYGCNGARACNGARGTNGCNMGNATGGARMGNGAR MGNGARGARCAYYTNCARCCNMGNYTNCAYYTNCARGARYTNAARCARCCNCCNCARCCN GTNGCNACNMGNGARTAYGARTCNGAYGAYGARCCNCCNACNTCNGGNMGN------GCN GARGCNMGNCARCCNCCNTCNCCNAARCARATHGARCAYCAYCCNTCNMGNAAYGGNACN CARCARCARCAYCCNYTNGTNCCNGAYCAYCAYCCNCCNCCNCARCARCARCARCAYMGN CCNTCNCCNTCNYTNTCNACNTCNCCNATHTCNACNGAYTCNMGNGTNAGYAGYNNNNNN NNNYTNTGYATGGAYGARCCNTCNCARTCNTCNTTYCCNCCNACNGTNGCNCCNCCNGTN CCNACNTCNTAY---GGNGARGCNMGNYTNGGNCARAARCAYTCNTCNGCNACNACNTCN TCNYTNAAYYTNGCNCCNGGNATHAGYCCNGAYTCNTCNAGYYTNCCNGGNATHACNAAY ATHTCNGAYGGNAARMGNAARAARYTNACNGTNGGNGAYGTNTTYAAYCARGAYGAYGAY GAYAGYAAYGARCCNAARAARMGNAARYTNATHCCNYTNGAYTAYGAYGAYGARAARTCN ACNCCNACNGAYAARAARGGNGGNACNGCNGARGARAARMGNCARAARATHAARCARYTN ATHGARAAYATHCCNACNGCNAARGAYGARYTNTAYGCNTAYACNGTNGAYTGGGAYATH GTNGAYCARGCNYTNATGGAYAARMGNATHAARCCNTGGGTNACNAARAARATHGTNGAR TAYATHGGNGARGARGARCCNACNYTNACNGARTTYATHTGYCARAARGTNATHGCNMGN AGYACNCCNCARAGYATHCARAAYGAYGTNGCNATGATHYTNGAYGARGARGCNGARGTN TTYGTNGTNAARATGTGGMGNYTNYTNGTNTAYGARACNGARGCNAARAARATGGGNYTN GTNAARYTNGTNACNGARGARTAYAAYCARCARGCNTCN---YTNTGGCCNCARGARGGN MGNCAYATHATGGCNCAYTAYGAYGAYGARACNGTNGTNGTNTAYCARGCNTAYAAYGCN AARATHGCNAGYCAYGCNGTNAARTAYCARCARTTYGGNGGNCCNGAYTTYAARTAYGAR MGNATGTCNTGGATHAARCCNAAYTTYATGTGGATGATGTAYMGNTGYGGNTGGGCNCAR AARCAYAAYCARGARMGNGTNYTNGCNGTNACNYTNACNAARCARGGNTTYGARAAYATH YTNGCNGCNGCNAARACN---------GGNAARGARGGNGGNATHGGNGGNGGNAARGAY GARGTNMGNATHCARTGGGAYCCNGAYCAYAAYCCNCAY---GGNACNAGYYTNACNMGN MGNGCNATHCARYTNGGNYTNMGNGGNATGGGNAAYTGYGTNCAYMGNTGYTTYGGNGTN ATHGAYMGNMGNAARMGNTAYYTNMGNTCNAARTAYAGYGARGARCARAAYTTYTCNATH GARTTYGARAAYYTNATGGARGARGARCCNCARGAYGARATGTCNMGNYTNYTNACNGAY MGNGARCARCARYTNYTNAARACNAARCARTTYACNGCNYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN GCNAAYYTNGTNTCNGCNTGYCAYAAYGGNAAYATGGARYTNGTNGTNTTYTTYAAYGGN GCNYTNGARAAYCARAARATHAAYGARTGGATGTCNCAYCARYTNTCNCARMGNGAYAAR GTNMGNTAYGTNYTNMGNCAYATHTCNAAYAARGGNACNCCNCCNCCNAARATHTGGTGG AAYCARCCNGTNTTYYTNAARGARGCNYTNAARATGGCNYTNMGNCARYTNGGNGTNACN GTNGCNTGYTCNYTNGAYGAYCAYCAYCARGARGTNATHAARTTYTGYMGNGARCAYACN YTNCARGGNATHATHGCNCARGARTCNGTNTAYACNATHTTYGAYCCNCCNMGNTAYTTY TCNTCNAAYAAYYTNAARYTNACNTAYAARGGNTCNYTNGARACNAARGARTAYATHATG GAYGARGTNGCNAARTGYATGAAYYTNAAYCCNAAYMGNTTYTGYGTNTTYGCNGCNYTN YTNGGNAAYCAYATHYTNACNGAYGARGAYYTNGTNCCNTTYMGNGARGGNYTNCCNGCN CCNGAYAGYGGNAARCCNMGNMGNCCNMGNGAYAARYTNGAYGCNCCNATGATHAARGCN ACNTGYGAYTAYGTNMGNAAYYTNCARTCNGTNGARAAYTGGGARTCNGTNGGNAAYGAY GCNTTYAARYTNGCNAARAAYAAYAARTCNGAYYTNGTNGAYMGNTTYAARAARAGYGTN AARTAYTAYGTNAGYGGNACNCARGARGGNTAYTTYAARTAYGTNYTNAAYMGNGGNCCN YTNATGTCNCARCCNATGTAYAGYGGNGGNCAYCCNCCNATHCAYGCNTAYGAYGAYCAY AARCAYCAYGGNAAYGCNATGGGNGAYGCNGCNCCNGCNMGNAGYGCNGGNYTNCCNCAR GTNTCNAAYGARATHATGMGNGTNGCNATHGAYMGNCAYCARAARGGNYTNATGCAYCCN YTNATHTAYCARGTNYTNACNCARGGNGARGTNAARYTNCCNGTNATHYTNGARGAYGAY ACNCCNMGNGAYYTNCCNAGYTAYATHGAYYTNTAYMGNCCNGTNMGNGGNACNATHTAY TCNGTNYTNYTNAAYYTNAAYAARCARAARATHGTNCAYGARATHCARGCNAARGARAAR TCNAAYAAYAARCARGGNGAYTTYACNGCNCARGTNAARGARTGGGTNGTNMGNMGNGGN TCNGGNMGNGCNGCNTAYGARGTNGTNACNGCNMGNCCNGTNGARTGGAARACNCCNAGY GTNCARMGNATGTGGYTNGGNCARCARGAYGGNGAYAARGAYMGNMGNYTNMGNGCNTTY YTNACNATHATGATGAGYGAYTCNAGYYTNATGYTNAAYACNAAYTAYATHCCNTCNCAY YTNYTNGTNATGTGYTGYGTNYTNMGNTAYATGYTNCARTAYGGNMGNATHYTNCARMGN CCNGARYTNGAYGCNTTYYTNGCNATGTCNGTNTCNCCNYTNYTNMGNGAYATHCARACN ATGCARGAYYTNAARYTNCCNCARATHATGCCNMGNGGNAGYCARYTNGCNTCNYTNTTY ATGGCNGGNATHGARACNGCNTGYATGGCNAAYGAYGTNTGYGGNGCNCCNATHCCNTGG ACNATGATHTGYCCNTGGYTNTAYATGGAYGGNAARYTNTTYCAYTAYAARYTNYTNAAR GCNAAYAAYAAYACNCCNYTNATHGAYGTNTGYGAYGGNCARATGGARCARGTNYTNMGN GTNGARMGNATGMGNCARGCNATHYTNGARAAYYTNCAYGTNGAYTTYGCNAARCCNYTN ATGGCNGGNTAYTTYTAYCCNTAYCCNGGNCARCAYGGNCCNGCNGGNCAYATGCCNTAY CCNCCNGCNGGNTCNGGNATGACNMGNGGNGGNMGNGGNGGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARAARAAYGAYACNYTNYTN AARMGNTTYAGYGAYCCNAARTTYATGTCNGCNYTNCARGARTTYCARACNAAYCCNCAR GCNGCNATGGARAARTAYAARGGNAAYAARGARGTNGARACNTTYYTNATGGAYTTYTGY GGNYTNYTNGGNGAYCAYTTYACNAARYTNGGNAGYAGYAAYGAYACNCCNAARTCNAGY CARACNCCNGGNTCNAAYGCNCARGCNGCNGCN--------------------------- ------------------------------------------------------------ ------------------------AARYTNAARCCNCARAGYGARTCNTCNAARTCNACN ACNCCNAARATHGTNGARYTNGGNAGYGGNGAYGTNCARACNACNAARCCNCCNAARTCN GARCCNATHAARTCNTCNAAYYTNAAYACNATHCCNAARCCNGGNGCNTCNCAYATHCAR ATHCAYGAYTCNCARAAYAARGCNGAYATHCARGARATHCCNCAYACNCARGAYGTNCAR CARACNGAYGAYGCNGTNMGNGARGTNYTNAAYGAYCCNAARGTNATGGARACNYTNATG GAYCCNAARATHATGGCNYTNATHAARACNYTNMGNGARGAYCCNGARAARGGNCARAGY YTNATHGAYAARGCNGAYGTNGAYYTNAARGARAARGTNMGNTTYYTNGTNGCNMGNGGN YTNYTNCARTTYCAR------CAYAAYAARGGNAARCCNTCNAAYGTNCCNTCNYTNGTN YTNCARGAYCAYGARAAYGARGTNYTNTTYCARACNYTNGGNMGNYTNTGYGTNACNYTN GCNACNGGNGTNGTNCARYTNTAYYTNGCNGAYCARAGYGAYMGNGCNMGNTGGAAYAAR MGNTGYTGYGGNGTNGCNTGYTTYGTNAARGAYAGYTCNAARMGNTCNTTYTTYATHAAR GTNTTYGAYATHAARAARCARCARATGATHTGGGARCARGARYTNTAYAAYCARTTYGTN TAYAARACNCCNMGNGARTAYTTYCAYACNTTYGARGCNGARAAYTGYCARGCNGGNYTN AAYTTYGCNCAYGARGAYGARGCNATHAARTTYAARAARGCNGTNGAYGGNAARYTNAAY GARMGNMGNCARAARAARATHGAYMGNAARCARAARTCNGTNTAYCAYAARGGNGAY--- ------AAYGGNCCNGCNAAYCCN------------CCNCARMGNATG---GGNAAYAGY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AAYGTNGCNGGNATGMGNAARGCNTAYAARGGNAAR CARGAYGTNTTYGAYGTNAARGAYYTNGCNTCNAARGARCCNTTYGARCARTTYAGYGCN TGGTTYGARGARGCNAARTCNACNCCNGARATHTAYGARGCNAAYGCNATGGCNYTNGCN ACNGCNAGYAGYGAYGGNAARCCNTCNGTNMGNATGGTNYTNATGAARGGNYTNAGYAAR GAYGGNATHGAYTTYTAYACNAAYTAYCAYAGYMGNAARTCNCARAAYYTNGAYGARAAY CCNTTYGTNTCNYTNYTNTTYTGGTGGAAYGTNMGNAGYMGNCARGTNMGNATHGARGGN AARGTNGARAARYTNTCNCARGARCAYTCNGARCARTAYTTYCAYTCNMGNCCNMGNTCN AGYCARATHGGNGCNTGYGTNAGYGARMGN---CARAGYTCNGCNATHACNTCNMGNGAR GTNYTNGAYAARMGNAARGARGAYYTNGARTCNCARTAYAGYGAYGARAGYATHACNATH CCNAARCCNGAYTAYTGGGGNGGNTTYMGNGTNGTNCCNGAYMGNTAYGARTTYTGGCAR GGNCARACNAAYMGNATHCAYGAYMGNATHGTNTTYMGNAARCCNCARACNGGNGARACN ATHGAYCCNTCNGTNACNTCNCARGGNAGYGARGGNTGGGTNTAYGARMGNYTNCARCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATHATHTCNGTNACNMGNGARGTN CARCAYACNAGYAAYCCNTGYTTYAAYATGCAYCAYAARTGYMGNGTNAAYAGYAGYGAY GAYYTNAGYTAYGCNGAYTTYMGNATHGGNCCNTGGAARGARAGYCARCCNGARGTNTCN GARMGNGTNTAYYTNMGNGCNATHATHMGNGARYTNGARTAYMGNGGNTTYACNGTNACN TTYTCNAARGCNGARATHTTYATHACNGARYTNGAYCCNATHATGGAYTAYCCNMGNCCN ACNYTNCCNAAYACNAARYTNATHGGNGGNACNGCNGTNAARGARGCNAARCCNYTNAAR GAYCCNTTYAARAGYTAYGTNGARAAYTCNAARAAYGGNATHATHGTNGTNTCNTTYGGN AGYACNYTNGTNAAYTTYCCNAARTAYATHTTYCAYAARATHAAYGCNGCNTGYGARGCN ACNGGNATGAAYATHATHTGGMGNACNGAYGARCCNTCNCCNAAYCCNAARATHATHYTN ACNGAYGARTGGATHCCNCARAAYGAYATHYTNGGNAAYAARAAYACNAARYTNTTYATH TCNCAYTGYGGNAARAAYGGNCARTAYGARTCNYTNTAYCAYGGNGTNCCNATHYTNTGY YTNCCNATHTTYGGNGAYCARAAYTAYAAYGCNGARMGNGTNAARACNAARGGNTAYGGN YTNAARGCNGAYATGMGNTAYATHTCNATGGARGARYTNTCNGAYATGATHMGNGARYTN GTNTCNAAYGTNACNTAYAARGAYAAYATHACNAARGCNTCNAARYTNTTYMGNYTNYTN TAYAARTCNCCNATGAARGARGCNGCNTTYTGGYTNGAYCAYGTNATHGARTTYGGNGGN GGNTAYATGMGN------------------------------------------------ ---------------------------------------------------------MGN AAYTTYCARCCNAGYAARATHYTNYTNMGNGGNTTYMGNAGYAARAARCCNACNTCNGAY YTNTCNAAYCARGTNCAYTCNGCNGARTCNGARGGNAGYTTYTCNYTNATHAARTCNGCN GCNTTYGCNACNGGNGTNTGYAGYTGYGGNTTYYTNGGNGCNATGATHTGGAAYTAYGAR MGNATHMGNAARATGTAY------ATGAARCCNAAYTCNGARGTNTCNAAYCARCAYCCN GARAARGCN------------TTYGGNATHAARGARCARYTNAARGCNATGTGGATHTAY MGNGARTGYTCNTCNAARYTNGTNTTYGGNATHGTNGCNGCNAAYATHGCNGTNTGYGCN YTNTGGAARGTNCCNMGNYTNCARGCNMGNATGATHCARTAYTTYTCNTCNTCNCCNGGN CAYCCNAARATHTCNATGGTNYTNAGYAGYTTYAGYCAYATHAGYATHYTNCAYYTNTTY GTNAAYATGTAYGTNYTNYTNTCNTTYGCNCCNGTNATHACNMGNGCNTAYGGNCCNGAR CARTTYTCNGCNTTYTAYATHGGNGCNGGNACNATGTCNGCNTTYGCNAGYATHATGTGY CARMGNYTNYTNAARMGNCCNYTNGCNATHTCNGTNGGNGCNTCNGGNGCNATHATGGGN YTNYTNGGNGTNACNGGNATHYTNTAYCCNAARGCNCARYTNCARATHGCNTTYGTNTCN GARATHTTYCCNCAYTCNTTYTCNGCNGARTCNGGNYTNAARGCNATHGTNYTNTTYGAY YTNYTNGGNYTNTTYATGGGNTGGAARGTNYTNGAYCAYGCNGGNCAYYTNGGNGGNATG YTNTTYGGNATHYTNTAYGCNAARTAYGGNAGYAARYTNGTNTGGGARAAYMGNGARTCN GTNYTNMGNGTNTGGCAYAGYATHMGNGGNCCNCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CCNAAYYTNAGYACNMGNGGNMGNTCNMGNTCNCARAARCAYYTN ACNMGNGARGARGARGARGARATHGARTAYGARAARCAYMGNCARCARCARTTYAARGCN CAYGGNGTNAAYCAYAARATHTTYCARGARTCNCARYTNGGNGTNCCNAARGTNCCNTCN AARCCNCCNACNACNGTNAARGARTTYAAYYTNCAYACNAGYAGYTCNGTNTAYMGNAAR GGNTCNAAYGAYYTNACNGAY---GARAARGCNGGNGARTTYCAYGCNAAYCCNGTNAAY CAYAARATHYTNGAYGGNCCNATHGGNATHAARCCNGTNGARAARMGNTCNATHACNGTN CCNCARTCNCCNGCNTTYACNYTNAARAAYMGNYTNMGNACNMGNGARMGNCAYCARCCN ATGGARGARGTNGCNCCNAARGTNTCNTCNMGNTCNGTNCCNCAYATGGGNGTNCCNTTY MGNCCNCARYTNGARCAYAARTAYACNGTNACNAARCCNTTYGCNGTNGARCARCAYAGY AARGAYATGYTNAARAARAARGARCARAARATHCARCARGTNTTYGAYGARGARAARAAR GCNMGNGARTTYACNGCNAAYYTNYTNCCNAGYGAYAGYCCNGAYCARYTNCCNCCNMGN AARACNAARCCNGTNACNTCNGTNGARCCNTTYAARYTNACNGTNGAYGARMGNGGNAAY AARTAYCARCARGARTGGAARTCNAARCARATHGARGARCARGARGARCARGCNMGNTCN AARGCNCARTTYCAYGCNTCNGCNAAYMGNGTNGTNTTYAARGCNCCNTTYGTNCCNGAY AARTCNGAYMGNCCNYTNACNGARATGAGYAGYTTYACNYTNAAYACNGAYCARMGNGCN GTNAARMGNGARTTYTTYAAYCARCARGTNAARAAYAAYGARGCNCARYTNGARGCNYTN AARMGNCARMGNGARGAYMGNAARGTNAARGARGARAARGAYGCNGTNACNCARYTNMGN CARGARATGGTNCCNAARGCNACNACNATHAARAARTAYAARCAYGTNACNCCNCARCCN AGYGAYAARCCNYTNACNATGGCNCARTCNCCNTGYYTN--------------------- ---------------CAYAGYAGYACNACNGARGAYCCNCAYGGNGGNGTNGTNATGGGN GTNCCNAAYAARTTYTGYGAYGAYGGNCARAGYTAYYTNTCNATHGAYTGGGAYCCNTCN GTNATGGAYGARCAYACNTGYTAYGAYGAY------MGNGAYYTNGAYATHYTNMGNGAY ---------AGYCAYGARGARTGYGARGTNATHGCNCARMGNCCNATHCAYGTNTGYTAY CCNGARAARATHGARTAYACNGARGAYYTNCCNACNAGYGGNMGNCAYMGNCCNYTNTGG CCNCARTAYGGNGARTAYMGNTAYYTNCCNCCNCARMGNTGGYTNCAYTCNYTNGARCAY GGNGCNGTNGTNTTYYTNTAYCAYCCNTGYGCNAARCARACNCARATHGAYGARTTYAAR GCNYTNGCNMGNGGNTGYATGMGNMGNCAYATHATHTCNCCNTCNAARMGNATHCCNYTN CCNAAYATGTTYGCNGTNYTNGCNTGGAARTGYAARATGGTNATGACNCAYGTNGAYGTN CCNAARATHGTNAAYTTYGTNMGNACNCAYGCNYTNCAYTCNCCNGARAGYACNGTNTTY GTNGAYGGNCARTAYAAYYTNACNYTNACNMGNCAYGCNGARYTNGTNTCNGAYYTNGCN GARACNAAYYTNTGYCCNAARATGTCNYTNATG---TAYGARCCNATHGAYTCNAAYAAR AARAGYMGNATHGAYGAYGARYTNYTNCCNGAYYTNGAYGAYGCNGTNYTNMGNATHGCN MGNATGMGNAARAAYCARGTNTCNAARTGYAARTCNGTNGCNMGNAAYACNGTNGCNAAY TCNGTNAARTAYTAYAGYCAYTGYACNGTNCARTGYGARGTNGGNGAYGARGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNTCNGAY GGNYTNGAYGGNGAYMGNTCNTGGGARAARCAYACNAAYACNTTYAARCCNCCNGTNCCN GTNGGNAAYAGYGAYTGYYTNGGNAAYGAYTTYAGYGARAAYGCN------AARAARAAY TCNTGYTCNAGYYTNTCNGGNGGNAAYCARCCNGGNACNATGGARACNYTNAARAAYATG YTNTTYAARYTNCARAARGARGARACNTCNACNGCNAGYAAYTCNAAYGAYAGYGTN--- ------------------------------------------------------------ ------------------------------ACNATGAAYGGNGARTCNTGYAGYAARAGY GGNCCNGTNYTNGTNMGNAARYTNGAYGAYGARTCNGCNTTYCCNTAYGTNGGNMGNGAR GGNCARGTNGCNTGYAGYGTNTCNAAYAARGTNTAYGTNTTYGGNGGNGTNGARCARGGN CARGGNGAYGARCCNAARGARACNAAYGARYTNYTNGTNTTYGAYYTNGGNTCNCARAAR TGGTCNAARCCNYTNGTNYTNGGNTCNCCNCCNGCNGCNMGNTCNGCNGCNTCNYTNACN GCNGTNGGNACNAARYTNTTYYTNTTYGGNGGNYTNAGYCAYATHTGYGGNTGGTTYGAY GAYGTNCAYGTNTTYGAYACNGTNTCNAGYACNTGGTCNYTNYTNGAYACNGAYGGNACN AARCCNMGNGCNMGNGAYAARYTNCARGCNGTNGCNTTYGAYTCNACNATHTAYTAYTTY GGNGGNTTYGGNCCNAARTCNGAYGARGCNGARGTNGAYGAYYTNGCNGGNGAYGAYGAY GAYGAY---GAYGAYTTYGARGAYATHCCNGARAGYMGNGARCARGAYGGNGCNGARTTY GGNTGGTTYAAYGAYYTNTGGGTNYTNGAYACNYTNACNYTNAARTGGTTYCARCCNATG CARATGAAYYTNGGNGTNCCNACNCARMGNGCNGCNCAYGGNATGTGYGCNGTNGGNMGN AAYATHGTNATHTTYGGNGGNMGNGAYATHGARGAYMGNCARAAYGAYGTNCAYATHTTY AAYATHGAYTCNMGNAARTGGGAYACNGAYYTNAARYTNAGYGGNYTNTCNCCNGCNCCN MGNTCNTTYCAYAGYGTNACNGCNGTNGGNGAYAARGTNGTNGTNTTYGGNGGNMGNGGN MGNGAYAAYAARCAYTTYTGYGAYTTYGAYATHYTNGAYYTNGARAARAARGARTGGTCN MGNGCNTCNGTNGARGGNTAYCARCCNCCNGCNMGNGGNCARCAYTGYGCNYTNACNGTN GGNGAYACNTTYYTNGTNTTYTGYGGNTCNGGNAAYTTYAGYCCNGARATHATGCARTGY CARACNTTYYTNACNGAYACNTTYTTYATHAARGCNGAYYTNTTY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GGNYTNTGGATHGAYATGAAYGAR CCNTCNTCNTTYGTNCCNCCNTCNTCNATGGGNTGY---CARAAYAAYACNTGGAAYTAY CCNCAYTAYTGYCCNAAYATHGARAAYTGYGTNATGTTYGAYAARACNATHTGYATGGAY TCNMGNCARAAYATHAGYYTNCAYTAYAAYGTNCAYAGYYTNTAYGCNCAYACNATGGCN ATGAARACNCAYGAYGCNYTNGCNTCNATHACNGAYAARMGNCCNTGGGCNATGACNMGN TCNTCNTTYGTNGGNACNGGNAAYTAYGTNACNAARTGGACNGGNGAYAAYCARGCNACN TGGCARGAYATGMGNAAYTCNATHATHTCNATHATGGARTTYGGNATHTTYGGNTTYGCN YTNAAYGGNGCNGAYATHTGYGGNTTYTGGYTNGARCCNTCNTAYGARYTNTGYGTNMGN TGGCAYCARYTNGGNGCNTTYTAYCCNTTYGCNAARAAYCAYAAYGGNGAYAAYTTYAAR GAYCARGAYCCNGCNTCNTTYGGNCARGAYTTYGTNGAYYTNATHAARCCNGCNYTNYTN ACNMGNTAYMGNATHYTNCCNTAYYTNTAYACNGCNATGTAYAAYGCNCAYACNGARGGN MGNYTNGTNATGCARCCNYTNTTYTTYCARTTYCCNGARGAYAARAAYACNYTNACNATH GAYMGNCARTTYATGYTNGGNGAYGCNATGYTNGTNTCNCCNGTNYTNGARGARGGNTCN GTNAGYGTNGARGCNTAYTTYCCNAARGGNMGNTGGTTYGAYTAYTCNACNGGNGARGAR ATHACNAGYGGNGGNAARACNGTNGAYYTNGCNACNCCNYTNAAYAARTTYAAYYTNCAY ATHMGNGGNGGNCAYGTNATHCCNTGGCARCARCCNAGYGTNAAYACNTAYCARAGYMGN YTNAAYGGNYTNGGNYTNATHGTNGCNYTNGAYGARACNGGNAARGCNAGYGGNGARYTN TTYTGGGAYAAYGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYCARGARTTYGGNATGTCNGARYTN GGNGTNGCNCCNGGNGAYMGNCCNYTNACNTGYGTNYTNAAYGAYCAYCCNGGNGARYTN GTNAARACNGGNAGYCCNAAYTTYYTNTGYTCNGTNYTNCCNTCNCAYTGGMGNTCNAAY AARACNYTNCCNGTNCCNTTYAARGTNGTNTCNYTNGGNGAYATHAARGAYGGNACNAAR GTNATHATHACNGCNGGNAAYGAYGARAAYTTYTGYTCNGARYTNMGNAAYAAYAAYGCN TCNATGAARAAYCARGTNGCNAARTTYAAYGAYYTNMGNTTYGTNGGNMGNAGYGGNMGN GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGYTNACNATHACNGAYTTYATHAAYATHYTNAARCARTAYTAYAARACN TCNGGNAARAARATHGARGARYTNGARGARCAYAARATHTCNACNTGGMGNGARGTNYTN AARGGNAARCARAARCCNTTYGTNTCNATHTGYCCNGAYCARAGYYTNTTYGAYGCNGTN AARACNYTNGTNGAYCAYCARGTNCAYMGNYTNCCNGTNATHGAYGARACNACNGGNAAY GCNYTNTAYATHYTNACNCAYAARMGNATHYTNMGNTTYATGCAYYTNTTYTTYAARGAR YTNCCNCAYCCNGCNTAYATGAARAARTCNATHAARGARYTNGGNATHGGNACNTAYGAR AAYGTNATHACNGCNACNCCNGAYATGTCNYTNATHGCNGTNYTNAAYYTNTTYTCNGAY CAYMGNATHTCNGCNYTNCCNGTNGTNGAY------TCNGGNAARATHATHGGNATHTAY GCNAARTTYGAYGTNATHAAYYTNGCNGCNGARAARACNTAYAAYAAYYTNGAYATHACN YTNAARGARGCNYTNGAYMGNMGN---TTYGAYAAYCAYGARGCNGGNGARAARGTNGTN TCNTGYCARTCNTCNGAYAARYTNGARGAYGTNGTNAAYAARATHGTNAARGCNGARGTN CAYMGNYTNGTNGTNGTNGAYGCNTCNGGNGCNGTNGARGGNATHGTNTCNYTNTCNGAY YTNYTNAAYTAYACNGTNYTNMGNCCNGTNGARGARGTNTCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYGGNGGNMGNGGN------GGNAAYTTYGGN TGGACNGCNCCNMGNACNCAYGARAARCARAARYTNCCNGTNTCNTAYGTNGGNAARYTN YTNGARGGNTTYTGYYTNTCNTCNAARCCNYTNCARCARMGNAARAARTTYCCNYTNCCN AARYTNCCNTCNGAYTTYAARCCNMGNCAYTGGTCNMGNMGNMGNAAR------GAYGAY GAYTCNGGNGGNMGNMGNMGNCARGAYCARATGACNGCNGTNGAYMGNGGNYTNATGYTN GGNGARACNCCNATHATGACNTCNGTNTTYGAYYTNGTNGGNTCNAARGAYAARTCNMGN ATGGARTGYGCNAARGAYGCNATHCARATGACNAARTCNYTNCARGCNTCN--------- ---------------AAYCARCAR---------ACNCAYGARGGNTCNGCNGAYGGNATH AARAARGAYAAYTCNTCNAAYGAYAARAGYCAR---CARCCNTCNAARTTYYTNTCNMGN TTYACNGARGCNACNACNTCNAAYACNGAYAAYGGNATHGTNGARAARAGYGGNGAYGCN CCNAARGCNCCNYTNTTYAARAGYTCNYTNACNATGCARCCNTTYMGNAARGARCCNTCN AARCARGCNMGNTTYGAYCARTTYYTNAAYGGNGTNCARCARAARGTNCARGAYCCNTAY AGYCARGTNTCNAAYAAYMGNATGACNGARTGGGARMGNTCNMGNGARMGNGAYGARTTY AGYMGNTCNGCNAARYTNTAYMGNCCNATGTCNGCNATGATGTCNGCNMGNTTYGTNCAR GTNTCNATGYTNGAYGAYAARAAYCARGAYTCNAARATGGARGCNGGNGGNGAYATHCCN GAYGARGTNAARGCNTCNGARATGMGNATGTTYGGNAARYTNACNMGNGARGAYTTYGAR TGGCAYCCNGAYAARYTNGTNTGYAARMGNTTYAAYGTNCCNAAYCCNTAYCCNGGNTCN GAYATHGTNGGNYTNACNACNGTNAARMGNGAYAARTTYTCNGTNTTYAAYTTYYTNAGY TTYGGNGAYTAYMGNCCNAARGARTCNGAYATHACNGTNAAYCARACNGARAARGAYGTN TCNGARAARGCNYTNTCNAARACNGCNGARTCNTCNAAYCAYAAR------AARAARAAR GCNACNYTNTCNTCNATHTTYAARGTNYTNGAYGAYCCNGAYTTYCAYAARCCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTN------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARGAYGCNGTNMGNAARYTNGTNMGN TCNMGNGAYATGTCNGAYGCNTTYYTNCARGARGTNCCNMGNAARTGGGARMGNCAYGGN GAYYTNGTNYTNYTNCCNTCNTCNACNTTYTCNTCNCCNGAYTGGAGYGTNYTNGGNGAY GARYTNTGGGARACNATHGCNTCNGTNYTNTGYTGYCAYMGNYTNGCNAARYTNTCNAGY GTNTCNGAYAAYGGNTTYMGNACNCCNCARGTNTCNATGYTNYTNGGNCAYGAYGGNAAR GTNGTNACNACNGAYAAYGGNATHAARTAYAGYTTYGAYGTNACNAARTGYATGTTYAGY TCNGGNAAYATHACNGARAARYTNMGNGTNGCNTCNTGGGAYTGYTCNGGNGARACNGTN GTNGAYYTNTAYGCNGGNATHGGNTAYTTYACNYTNCCNTAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TAYGTNGGNCAYCAYTAYGCNGGNCCNGGNAAYCAYTTYTGGAARTAY GAYGAYTTYAARYTNCCNAARTTYGGNATHGGNTTYACNAAYATHTGYCCNMGNACNACN MGNGGNAGYTCNGAYYTNMGNAARAGYGARATHAARGARGGNGGNGARGTNYTNAARMGN AARATHYTNAARTAYMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNGARGCNCAYGTNAGYMGNYTNGCN GTNGARAARGAYAARMGNACNAGYGARTTYAAYGAYYTNAARGGNAARGTNTGYGAYYTN TAYAAYATGATGGARGTNGAYCCNGARTCNTCNTTYGCNCAYGAYGTNGTNTGYGARGAY GTNGAYACNTTYACNYTNTCNACNACNAARYTNAGYAAYYTNAARATGYTNTAYGAYGAR YTNGTNMGNMGNGAYGAYCARATGAARYTNGAYGTNGARGAYYTNTGGGAYMGNYTNAAR GCNYTNTGGAAYMGNYTNGARACNCCNGARATHGARMGNGARGCNTTYTCNYTNGAYAAR ACNGGNCAYGGNCARAARGTNATHAGYGAYATHAARTCNGARATHGCNGTNTGYGARGAR YTNAARYTNCARAAYATHCARAARTTYATHGARGGNATHMGNACNGARYTNGTNTCNTGG TGGGAYAARTGYTTYTTYGAYCCNCARGARMGNAGYAGYTTYACNYTNTAYTAYGARGAY AAYTTYACNGARTCNYTNYTNGARGCNCAYGARMGNGARYTNGARAARGTNMGNGAYTAY TTYAARGARCAYMGNGARATGYTNGAYAARGTNTCNMGNMGNGARGTNATGTTYAARACN ATGGTNGARTTYGAYAAYAARGCNAGYGAYCCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATHGTNCCNAAYTCN AGYYTNAAYTCNTTYGGNTCNATHTGYTAYTGYGTNATHACNATGGGNATHCAYGCNTAY GCNTGYTAYAARGAYATHGTNMGNTAYCARGARGCNGAYGARMGNGCNTGGCCNAGYAAY GGNGGNGARCCNCCNACNGARGTNTCNGCNYTNYTNGGNTTYACNATHYTNTCNYTNYTN GTNACNCCNYTNTTYTGYGTNGCNTCNTTYATHAARGTNGGNAAYYTNGCNAAYGAYGGN GTNAARYTNGGNMGNGAYCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNTTYGGNAARTAYACNCCNGARAAYYTNGAYGCNTCNYTNTGYAGY CAYATGCAYTAYGCNTTYGCNAARTTYAAYCCNGAYCAYACNATHGCNCCNTAYGARTGG AAYGAYGARAGYACNGARTGGAGYGARGGNATGTAYGARAARTTYAAYGAYYTNAARAGY TCNCAYCCNGGNYTNAARACNGTNYTNTCNYTNGGNGGNTGGAAYYTNGCNTCNGCNCCN TTYTCNAGYATGGTNGCNTCNCARCARAAYMGNGCNGTNTTYATHAARAGYGTNGTNGCN TTYYTNMGNAARTGGAAYTTYGAYGGNATHGGNATHGAYTGGGARTAYCCNGGNAAYMGN GGNAGYCCNGCNGGNGAYAARGARYTNTTYACNGCNYTNGTNCARGARACNATGGCNGCN TTYCARCARGARTCNGTNYTNACNAAYMGNCCNMGNYTNTCNYTNTCNGCNGCNGTNTCN GCNGGNAARAGYACNATHGAYTCNGCNTAYGARGTNGAYAARGTNACNAGYGTNYTNGAY TAYGTNGTNGTNATGACNTAYGAYTTYTTYGGNGCNTGGGAYCCNTAYACNGGNYTNGTN GCNCCNYTNTAYCCNCCNAARAAYGCNACN---GGNATHCAYGCNATHTTYAAYACNGAY TAYGCNGTNAARTAYTGGGTNTCNAARGGNTGYCCNAARAAYAARYTNGTNGTNGGNGTN ATHTCNTAYGGNMGNTCNTAYACNYTNACNAGYACNTCNCARACNGGNYTNAAYGCNCCN GCNAAYGGNGCNGGNACNCCNGGNACNTAYACNMGNGARGCNGGNTTYYTNTCNTAYTAY GARGTNTGYAARATGATHAARCARGGNGCNAARATHGTNMGNYTNGCNGAYGARAARGTN CCNTAYYTNGTNYTNGGNMGNCARTGGGTNACNTAYGARGAYAARGCNAGYYTNATGATH AARGGNAAYTAYATHAAYAGYGGNGGNTAYGCNGGNGCNGCNATHTGGTCNGCNCCNYTN GAYGAYTTYAAYGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TAYGCNATGCCNTCNTCNAARTCNCCNYTNATHTGGACNGGNGTNATHTTYATHMGN CARGGNYTNTAYCARGGNGCNGCNYTNMGNTTYACNYTNACNATHCCNCAYAAYTAYCCN GAYGGNAAYTGYCCNACNYTNGTNTTYGARCAYCCNGTNTTYCAYCCNYTNGTNGAYCCN GAYACNGGNGARYTNGAYGTNAARMGNGCNTTYCCNMGNTGGMGNMGNAAYGTNAAYCAY YTNTGGCARGTNYTNYTNTTYNNNAARAARGTNTTYTAYAAYATHGAYACNAARATGCCN TCNAAYCCNGARGCNGCNGTNYTNTAYGARCARGARCCNGARYTNTTYAARAGYAARGTN TCNGARTCNGTNGARGCNGCNMGNGARMGNYTNTAYCARCCNCCNTCNYTNGAYGAYCCN TTYGCNYTNMGNTTYAGYCCNTGGAAYGARGCNGTNCAYCCNGAYACNMGNMGNCARATG GTNCARACNTCNAARAARAARTGYGARGGNGAYAGYTCNGCNAAYCCNTCNGAYYTNGGN YTNAGYTGGATGGARTCN------ACNCAYATHTTYGCNACNGAY--------------- ------------CCNYTNTTYYTNTAYYTNGCN--------------------------- ---------------------------------TAYCARTCNGTNCAYGCNCCNYTNCAR GTNCCNCAR---AARTAYTCN---------AARAAYCAYAARMGN---------MGNACN TAY------------------------------GCNGGNATGGTNTCNGCNATGGAYGAR GGNGTNGGNAAYYTNACNCARGCNYTNAARGAYGARGGNYTNTGGGAYAAYACNGTNTTY GTNTTYTCNACNGAYAAYGGNGGNCARGTNCAYGARGGNGGNAAYAAYTTYCCNYTNMGN GGNTGGAARGGNTCNYTNTGGGARGGNGGNTTYCAYGGNATHGGNTTYGTNTCNGGNCCN AARGTNAARTCNCCNGGNACNGTNACNAARGARYTNATHCAYGTNACNGAYTGGTAYCCN ACNYTNGTNAARYTNGCNGGNGGNAGYYTNAAYGGNACNAARCCNYTNGAYGGNTAYGAY CARTGGGAYACNATHAGYTCNGGNAARCCNGGNAARMGNCAYGTNYTNYTNCAYAAYATH GAYATHYTNTCNAARAARAGYGGNGARMGNYTNTAYAAYAAYACNTTYGAYACNMGNGTN MGNGCNGCNATHMGNGTNGGNGAYATGAARYTNATHACNGGNAAYCCNGGNAAYGGNTCN TGG--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CAYCAYMGNYTNTCNGGNCARAGYTAYGARTCNGGNGTN TCNTCNMGNCARAGYTAYCAYTCNACNTCNTCNTCNTCNCAYGGNAGYYTNGAYMGNYTN GARGAYCCNGGNYTNCCNTCNACNATHAAYGTNACNCARYTNTTYCARGCNGGNGTNCCN GAYTCNGARGTNYTNCAYGCNTGGYTNCAYGAYYTNGGNTTYGARGARGTNTTYCCNYTN TTYYTNCARGCNGGNTAYGAYATGCCNACNATHTCNMGNATGACNCCNGARGAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATHGARAARGARATHTCNMGNMGNAARAAYTTYCAYCAY AAYGCNTTYGARMGNTAYCARGTNGTNTCNGAYACNTAYCARCCNYTNCAYTCNCAYYTN TGGGAYTTYAARCCNTCNTTYATGGAYGAYMGNYTNCCNAARATHGTNGCNATHYTN--- CAYACNTCNAAYATHGARGAYGTNGARMGNGCNATHATHCARAAYGGNGGNAAYGTNYTN GGNGCNCAYYTNTAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNCCNCCNATHTGYACNAAYAAYTAYGARMGNGAYCCNAARGGNACNACNTAY GGNTAYTTYTTYTGYCCNATHYTNAAYGARACNGARTCNCARMGNTAYTGYTGYGGNCCN MGNAARMGNGARCAYTGYTGYGAYYTNACNGARGCNAARATHTAYTAYGGNACNCAYCAY TCNAAYAARGGNGGNATGGCNGCNGGNGCNATHGGNGCNATHGTNGTNGCNYTNATHGTN GTNATHGTNTGYGTNGTNTGYTGYTGYAARAARAARAARCARYTNGGNTCNATHATHMGN MGNGGNTCNAGYAARGARGARGGNTCNCCNGGN--------------------------- ---------CARCCNCCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GCNGGNGAYGAYMGNAAYTTYTCNATHGARACNACNTGGGAY GGNCARTGYTTYTGYCAYGAYCCNGTNAARATHTTYYTNGGNCARAGYGCNAAYGGNGAY YTNYTNYTNAARGTNGAYGCNCCNTTYTTYAAYAGYCCNGCNAARCCNAAYGGNCCNGCN GGNCARCCNTTYCCNCARYTNTGGGAYTAYGARGTNGTNGARGCNTTYTTYYTNAAYGAY CARGAYCARTAYYTNGARGTNGARYTNAGYCCNCAYGGNCARCAYYTNYTNYTNYTNYTN AAYGGNMGNMGNAARATGGTNAARGAYAARYTNCCNYTNAAYTTYACNGCNACNATHACN GGNGAYAARTGGAGYGGNGARGCNGTNATHCCNMGNGAYTAYYTNCCNTCNGCNGTNACN AARTTYAAYGCNTAYGCNATHCAYGGNGARGGNGCNGARMGNCARTAYGARGCNYTNTAY CCNGTNACNGARATHAAR---------GARGGNATGCARCCNGAYTTYCAYMGNYTNGAR YTNTTYMGNCCNATHGAYATGAGYGCNATHYTNAGYAAYTAYGTNCCNTCNCAYGTNTCN ACNYTNTGG--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYGCNTCNAAYGAYGARYTNTAYAGY AARATGMGNMGNCARMGNATHYTNMGNGARGARYTNMGNTCNAARAARAARGARYTNGAR GCNATHATGAARAARGAYMGNAAYAARMGNCARTAYTCNMGNAAYCARGAYAAYCARAGY GAYACNGTNTCNYTNAAYACNGAYACNTTYGGNATHCCNGCNAGYGTNGAYGCNGARGAY GARGAYGGNAAYGCNGAYGARGAYGARGAYGGNTAYCCNAGYGAYGGNATHGTNCARGTN GARGARGARGARGARGARAAYGAYACNGAYAAYGGNACNTAYACNATHGARGCNGAYGCN MGNCARMGNAARCAYATGMGNAARCCNGGNCAYATGGGNATHGGNGCNMGNCCNAARACN TCNMGNGGNMGNCARACNTTYCCNCARCCNGCNTAYTCNGAYCARGCNACNAARAARGTN TCNAARAARACNAARMGNAAYGCNCARAGYAARCARMGNGARTCNAARATHMGNCARGAR AAYTAYMGNTCNGCNGARGAYYTNATHCAYGARGARGARGTNAARGGNAARAAYCCNGAR TGGTTYMGNCAYATGGARAGYMGNATGAAYAAYYTNAGYTCNTCNGTNGARTCNYTNGTN AARAARYTNGAYACNGGNGGNMGNCARYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GCNCAYCARCARGARYTNCAYGGNAGY AARMGNCARTTYYTNTGYMGNTGYTCNTTYYTNGARATHTAYCARGARCARATHTTYGAY YTNYTNGAYCCNACNTCNCARGGNYTNCAYYTNMGNGARAAYATGAAYAARGGNGTNTTY GTNGAYGGNYTNATHGARCARGTNACNTGYAGYCCNAGYGAYGCNTAYCARGTNYTNATH ATGGGNTGGYTNAAYMGNMGNGTNGCNGCNACNTCNATGAAYMGNGARAGYTCNMGNTCN CAYGCNGTNTTYACNGTNACNATHGARTCNAARGARGARGTNGAYGGNGTNCARAAYATH MGNACNTCNCARYTNAAYYTNGTNGAYYTNGCNGGNTCNGARMGNCARAARGAYACNAAY ACNGTNGGNACNMGNYTNAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CCN CAYTTYTTYGGNTCNATGACNYTNAARGCNYTNYTNGARGAYCCNAAYYTNAARAAYCCN CCNATHATHGGNCARTCNAAYAAYYTNGCNAARGTNAARAARGARGAYGGNTCNTCNGAY GGNGTNMGNTAYAAYTAYGGNTCNGCNTTYYTNGGNCCNACNYTNTGGGAYAARTCNTAY GGNATGGAYYTNAAYYTNGARTAYATGGAYYTNGAYGARTTYYTNTCNGARAAYGAYATH CCNGTNGCNGGNGARGARCARGARGGNYTNGCNGGNYTNGAYGCNAGYAARGAYGAYGAR ---GAYTCNYTNYTNTGYGGNGTNAAYACNCCNCCNAAYCCNGTNGTNAGYTCNCCNMGN CARTAYYTNMGNACNCCNCCNATHAGYCCNTCNCAYTTYAGYGCNCARCCNCCNGTNGCN TTYCCNACNCAYTCNMGNTCNCCNYTNCCNACNGCNTCNCCNTCNTCNCCNACNACNTCN CCNCCNMGNAGYCCNTCNTTYAARGTNGAYTTYCARGTNTCNGAYCARGAYYTNGCNYTN ACNTCNATHCCNGAYTAYGAYGAY------------CCNMGNTAYTAYCCNGGNGGNTGG ATGCARGGNGGNGARGGNCAYMGNCCNAARATGGGNGCNAGYTTYGAYCCNMGNAARMGN AAYTTYTCNGARGARGARYTNAARCCNCARCCNATHATHAARAARTCNAARAARATHTTY GTNCCNGARGAYYTNAARGAYGAYAARTAYTGGGCNMGNMGNYTNAARAAYAAYTAYGCN GCNAARMGNTCNMGNGAYGCNMGNMGNGTNAARGARAAYCARATHGCNYTNMGNGCNGCN TAYYTNGARAARGARAAYACNTGYATGAARGARGARATGGCNAARATGMGNAARGARAAY GCNAARYTNAARACNATHGTNGARAARTAYGARCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN MGNGAYGCNGAYGCNGCNMGNTCNMGNCCNMGNTCNGGNTCNTTYTCNAARYTNCAR--- GGNCAR---GCNTTYATHACNCARAARAAYGARMGNTCNYTNMGNTAYGARTCNACNAAR CCNGTNTAYGTNTTYCCNAARCARTCNCCNACNAARCCNMGNMGNAAYTCNGAYGAYMGN ATHTCNCARYTNGTNMGNTCNAAYAGYCAYTCNGGNYTNATGTCNCARACNGAYGTNATH AGYGCNCAYAGYGCNGCNAARGTNCAY---------------------TCNTCNAAYAAY AAYAAYCARACNATGTCNCARGAYAAYTTYGGNGTNGARAGYTTYACNGAYAAYGCNCAY AAYTAYAAYGGNGAYAAYGGNGAYTTYGARAAYGCNGARATHGAYTCNGTNCARAGYAAR CCNCCNATHTCNATHMGNGTNAARTCNGCNCAYACNMGNMGNCCNGCNCAYATHGAYGAR TTYGCNGAYGARGARMGNGCNYTNMGNGAYATGGARGCNGAYTTYAARAARACNGCNYTN ACNYTNCARAARMGNYTNGGNYTNCARGARACNGGNATHATHACNYTNGAYAARAGYTAY YTNGARTCNGTNAARCCNGTNGTNACNGAYGARGARTTYMGNCARACNGARTTYYTNTGY CARCARTTYGCNTCNGGNGTNGGNAARGARYTNCARCARATGYTNCAYGARMGNGCNAAR GGNAARMGNAAYTGGYTNGARAARTGGTGGGARGAYGCNGCNTAYYTNGARYTNMGNATG CCNYTNTCNYTNATHAAYATGGGNGGNCCNGGNTCNTAYATGGARGAYATHTGGCCNCCN CARGARGGNACNCARYTNTTYMGNGCNGCNATGTCNGCNTAYCAYACNGTNAARTTYTGG CARTAYGTNCAYMGNGARCARTAYMGNCCNATGAARGAYGGNAAYGGNMGNCCNATGTGY ATGTAYCARTTYMGNMGNGTNTTYAAYGCNTGYMGNGTNCCNGGNGTNTTYMGNGAYAAR YTNATHGARTAYTTYAARACNGARTCNGARGGNGARTGYCCNTCNCAYATHATHGTNATG TGYAARGGNCAYATGTTYATGATGAAYACNYTNGAYGAYGCNGGNGARGTNYTNACNCCN YTNGARTTYGARGGNCARTTYMGNMGNGTNMGNCARGARGCNGARAARYTNGGNGCNCCN CARGARGTNAAYTAYYTNACNACNYTNCCNMGNACNGCNTGGGCNGARTAYMGNAAYATG YTNYTNGCNAGYCAYCCNCAYAAYTAYGARGTNYTNGARAARATHCARAGYTCNATGAAY TTYTAYAGYYTNGAYGAYGARAAYGCNGTNGAYYTNACNGAYYTNGCNAAYAARTCNATH YTNGGNAGYGTNCARAAYMGNTGGTGYGAYAARTCNYTNTCNATGGTNACNTAYAAYAAY GGNACNYTNYTNTGYAAYGCNGAYCAYTCNTTYTGYGARGGNATHATGATGGTNTAYGTN TGYGGNTAYGTNCAYCARAARYTNMGNGARTCNAAYGGNYTNTGGCARGGNACNAARGCN GTNMGNCCNCARCCNCCNCCNGTNCCNYTNAARTTYGTNGTNCCNGAYGARGCNMGNCAY GGNATHGARATHGCNAARACNGCNTAYAARGARYTNCARAARTGYGCNGAYTGYGTNATH TTYAARTAYAARGGNTAYGGNAARACNTAYTGYAARCARAAYAARYTNCAYCCNGAYGCN TTYTGYCARYTNGCNYTNCAYYTNACNTTYTAYACNYTNCAYGGNMGNATGGCNCCNGCN TAYGARACNGCNGCNATHAARCARTTYTAYCAYGGNMGNACNGARACNYTNMGNTCNTGY ACNATGGARGCNTTYGAYTGGTGYMGNAGYATGTCNGAYAGYTCNTGYTCNAAYACNGAR MGNTTYAARYTNYTNTCNAARGCNGCNGCNAARCAYAAYAARAARATGTCNGAYGCNTGY GARATGAARGCNTGYGAYMGNCAYYTNATGGGNYTNGCNYTNGTNGCNAARGARGARAAY YTNCCNATGCCNATGYTNTTYCARGAYCCNTCNTTYGTNAARAGYGGNGGNGGNGGNAAY TTYYTNYTNTCNACNAGYACNGTNGGNTAYTCNACNATHATGGGNGGNGTNYTNCCNATG TGYGARAAYTGYTAYGGNTGYTTYTAYMGNATHAAYAAYAAYATGATGACNTTYTTYATH TCNACNTGGAAYGCNGAYAARATGACNAGYAGYMGNGGNTTYGARGARGCNYTNGGNAAR AGYYTNGAYMGNATGAARGARGTNATHGAYCARGCNACNAGYACNGCNAARGCNMGNYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GTNCCNGGNGARCAY GARCCNGCNTAYAARGTNAAYATHATHATGACNTGYCAYGCNTAYGGNCCNGARGAYTAY GTNTTYAAYTGGAARCAY---TGYGTNMGNMGNGAYAAYMGNGAYYTNGGNATGCARCCN TGGYTNGTNCARAAYGAYATHACNACNGARACNCCNCARCARATHGGNGAYGGNTCNTGY GGNGGNTAYMGNCAYTCNGARTCNYTNAARTTY------ACNGTNACNGAYGAR------ ATGCARMGNTGYACNGTNTTYTGYGARTTYGGNGGNGARYTN------------GAYGCN AAYTTYACNTAYATHATHGARGAYATHGCNACNCCNATHCCNGGNAAYGGNAARGCNGGN CARAAYAARGCNTCNAGYGGNTCNGTNATHGGNYTNACNGTNTCNYTNYTNYTNGTNATH ATHGTNGTN---GCNGTNYTNGTNTAYGTNTGYTGGTGGMGNAARMGNACNCCNAGYCAR GAYAARTAYAARGAYGARCCNGAYGTNGGNCAYAAYAARGAYCARGAR---------GTN CCNCCNGTNTTYTAYTCNAARCCNCAYAARGCNCCNAARGTNGAYGAYATHGARGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNACNTGYGGNGGNACNATHGAYAARCARTAYCCN CARGGNCCNGGNGCNTAYGCNTTYGARTTYGGNAAYGCNGCNGTNGARAARATHTTYCAR MGNATHTGYCCNTCNTTYCARTAYAARGTNGAYACNATHTGYGCNAARGAYAGYCARGAR ATGACNGAYCAYGAYMGNGARGCNGTNYTNMGNGCNATHYTNGAYGCNTCNCARCARYTN ATHYTNATHACNCAYGGNACNGAYACNYTNTGYGAYACNGCNCAYTAYYTNAGYAARGCN GGNGTNGGNCARAGYGGNCARTTYGGNTCNGARGCNGCNGGNAARACNGTNATHYTNACN GGNGCNTTYAARCCNGARGCNATGAARGAYTCNGAYGCNGAYTTYAAYATHGGNTTYGCN YTNGGNTTY---GCNAGYTCNTCNATHCCNGGNGTNTTYGTNGCNATGGCNGGNAGYATH YTNGAYGGNAAYCAYGTNATGMGNTGYGARGAYGGNMGNTTYGTNGAYGARMGNTTYGTN YTNAARMGNTTYGAYACNATHGGNGAYTTYGTNTAYATHAARYTNCAYTGYCCNTTYAAR MGNATHTGYGTNGARGCNGARMGNGTNCAYATHGARATGCCNYTNMGNGAYTGYGARGTN CCNGARACNGTNATHMGNAAYCCNATHATGMGNTTYATGGAYGARAARYTNGAYGCNGAR AAYGAYGTNAAYGAYTTYGTNAGYGCNCARTTYATHATGGAYAARATHCAYYTNTTYGAR GGNTAYGARGAYCCNACNAARTTYTTYMGNCCNGCNATHMGNTCNYTNYTNGTNCAYCAY ATHYTNATHAAYYTNGAYATHMGNACNGCNCARGARATHGARGARGAYGAYGCNAGYGAR AAYGARAAYGARGAYACNAGYTGYATGTGYYTNCCNGCNGCNTGYMGNAGY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGYTNTCNMGNTCNGGNMGNGCNGARACNMGNAGYMGNGCNAARGAR GAYATHAARMGNGTNATHAAYGCNATHGAYAARGTNMGNAARTGGGARAARAARTGGGTN ACNYTNGGNGAYACNTCNGTNACNATHYTNAARTGGGTNCCNGTNACNGCNCARGARAAY CCNGGNGCNYTNMGNAARATHCCNGGNGTNAARACNAARACNTAYTCNAARGCNMGNGTN GARMGNGARMGNGARYTNTAYAAYGCNGARACNAAYTCNTCNYTNMGNGCNAAYTCNCCN GCNGAYTCNACNAGYAAYAAYACNAAYATGTCNAAYACNAGYTCNCCNTCNTCNAARAAY CAYAAYACNGARAARAAYAARAAYGGNAAYGGNAAYGTNACNAAYAGYCARAAYTCNGTN GTNTAYTCNGARGARAAYACNCARCARTCNATHGGNTCNTTYGGNTCNGARAAYYTNAAY GARGAYTCNAAYATGTCNTTYCCNGARAAYAGYGGNATGAGYGARCARGGNGAYCAYAAY GARTTYTCNCAYGAYAGYAAYGAYGCNGAYCCNGGNATGMGNGTNGCNATGAGYATGGTN GGNGAYGARGARGARGARGGNGARAAYAARGCNGCNACNAARACNGAYGARGGNCCNCCN GARCARGAYAARGAYTCNTCNTCNGARGARCCNCARCCNAARAARGCNAARACNCCNTCN ATGTCNGARAARCAYAGYTTYGGNATHGCNCCNGTNACNTGYCAYGCNTTYAGYAARGAY MGNAAYGGNYTNGCNATGTCNYTNAAYGAYTCNAAYGTNAARATHTAYAARAARGCNGGN AAYAARTGGGAYGARACNGAYACNYTNAGYGARCAYGGNCARMGNGTNACNAGYATHGAY TGGGCNCCNAAYAGYAAYMGNATHGTNACNTGYTCNGCNGAYMGNAAYGCNTTYGTNTGG ATGYTNGARGAYGGNAARTGGAARCARGTNYTNGTNATHCCNMGNATHAAYMGNGCNGCN ACNTGYGTNAARTGGTCNCCNAARGARAAYAARTTYGCNGTNGGNAGYGGNTCNMGNYTN ATHGCNATHTGYTAYTAYGAYGAYGARAAYAAYTGGTGGGTNAGYMGNCAYATHAARAAR CCNATHMGNTCNACNGTNACNTGYYTNGAYTGGCAYCCNAAYAAYGTNYTNYTNGCNGCN GGNTCNACNGAYTTYAARTGYMGNGTNTTYTCNGCNTAYCARAARGARGTNGAYGARMGN CCNGGNGCNTGYAGYTGGGGNACNAARATGCCNTTYGGNGCNYTNATGGCNGARTTYAGY AAYGGNGGNGGNGGNTGGGTNCAYTCNGTNTCNTTYTCNCCNAGYGGNACNYTNGTNGCN TGGGTNGGNCAYGAYTCNAGYGTNTCNATHGTNGAYTCNTCNAARGGNAAYGARYTNGCN YTNATHAARGARAGYTTYYTNCCNTTYATGAGYATHTCNTTYGTNACNGARAAYTCNYTN GTNGCNGCNGGNTAYGAYTGYAAYCCNATGGTNTTYTCNTTYGCNGGNGGNAARATHACN TCNCARGGNAARYTNGAYGTNCCNCARGARAARGCNTCNGGNACNATGAGYGCNATGAAY MGNTTYAARAAYYTNGAYAARAARGCNACNGAYAGYGAYAGYTCNCCNGARATGAAYACN CARCAYCARAAYACNATHACNCARGTNTCNATHCAYACNGGNGAYAARCARGAYGCNAGY AARATHGCNACNAGYGGNGTNGAYGGNAAYYTNATHATHTGGGAYYTNAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TGYGAYYTNTGYCCNTGYCCNTCNYTN ACNGCNTAYTGGACNAAYCCNCCNTCNTGYCCNMGNMGNGTNTGYTGYGARAGYAARTCN TCNTGYTGYGCNTTYAGYTGYTTYMGNGAYACNMGNACNGTNTCNGTNTTYGTNGCNACN GTNTTYATHACNTAYTTYATHTTYATGGAYATHYTNYTNTAYTGYTAYTAYATGAARGCN AAYYTNGTNGARGGNTCNAARGGNGGNGGNGCNGAYGARATHTAYACNCCNTTYACNCAY YTNTCNGTNAARGCNYTNYTNAAYGAYCARCCNAGYCARTAYYTNATHGCNCCNAGYACN GARTGGYTNGARTAYTTYACNAAYTTYGCNACNACNTTYTAYTTYATHACNCCNAAYGTN GTNTCNTTYACNCAYYTNATHGTNGGNTTYATHTCNGGNAARTTYGTNTCNTCNGAYAGY YTNAAYGAYMGNMGNATHGGNGTNATHYTNTTYGARTTYMGNACNTGGYTNGAYGCNTTY GAYGGNACNATHTTYMGNGCNCARCCNGGNAAYCAYYTNAARTAYAAYTCNGTNCAYAGY ACNYTNGGNTAYTAYATHGAYTCNGTNTTYGAYAGYYTNGGNGGNGCNTTYYTNTGYTTY GGNATHTAYTTYTAYYTNATGAARMGNTTYGGNCCNCCNMGNTTYCARTGYGTNYTNCCN TTYTGGTCNTCNTCNTCNGARAGYCARAAYAARGTNCCNYTNGTNAGY------------ GARGGNGGNAARGARAGYTAYTCNTCNYTNTAYYTNTTYTGGAARGCNTTYTCNTTYGGN ATGGTNYTNYTNGTNTCNGCNGGNGCNTGGGAYAAYATHGTNGTNCARTTYTCNGARGTN TTYCARACNGARYTNGCNGAYCCNAARYTNGCNGCNGTNCARYTNGARTGGTCNCAYTGY AAYACNACNGTNTTYATHTTYCARYTNTGGMGNYTNATHGGNTCNCARTGYATGYTNAAY TAYATHYTNATHATHYTNTTYTGYGAYAARGTNTGGGARTTYYTNAARGGNACNCARTAY YTNYTNATGGTNATGATHGTNAGYYTNTAYATHATGTCNACNATHTAYGTNAAYCARATH MGNAGYCARYTNAAYYTNCCNAARATGATHGTNTTYGAYYTNGAYTAYACNYTNTGGCCN TTYTGGATHGAYACNCAYGTNAGYCCNCCNTTYAARAARAAYCCNGAYGGNAARATHMGN GAYGCNMGNAAYGARCAYGTNAARTAYTTYCCNGAYGTNCCNGARATHYTNGCNAARYTN CAYTCNGAYGGNTAYATHYTNGGNATHGCNTCNMGNACNGGNGCNATHAARGAYGCNGAR GAYYTNGTNMGNYTNTTYGGNTGGGAYAARTAYTTYAGYTAYAGYCARATHTTYCCNGAY TGYAARATHACNCAYTTYAARGCNYTNCAYAARACNAGYAARATHCCNTAYACNGAYATG YTNTTYTTYGAYGAYGARCAYMGNAAYATHAARGAYGTNTCNTCNYTNGGNGTNACNTGY ATGTTYGTNCCNGAY---GGNGTNACNCAYGARTCNYTNCARGARGGNATGGAYYTNTTY AARTCNAAYAGYTCNAARMGN--------------------------------------- ------------------------------------------------------------ GGNYTNATGGCNGARATHTCNYTNGAYACNMGNTCNAGYTCNAAYMGNCCNTCNACNGAR AAR---CCNTAYAAYTCNGAYGGNGAYGARACNMGNACNTCNGARAGYAGYGCNMGNAAY GARGAYCAYGCNGAYGCNGAYCARGCNYTNGCNGAYATGTGYGARATHYTNCCNCCNTCN ATGMGNAAYYTNGAYACNTCNACNGAYGTNGAYAARATGGTNTCNACNTTYCARAAYCAR MGNMGNCARYTNGARTCNMGNTAYCARGARYTNAAYAAYCARGGNYTNGCNCARAARGTN TTYMGNATHYTNACNAAYCARGAYCCNGARTCNCAYGCNAAYGGNATHYTNTCNGARATH AGYGCNGAYGARAARGAYATGMGNACNMGNATGGTNYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNGAYTCNTGGTCNGTNATHYTNAAYGGNGARGTNGARATHGTNMGNCCNGGN GGNGTNMGNGARMGNYTNCARATGGGNGAYAGYTTYGGNATHAGYCCNACNATGGARAAR YTNCAYCAYCARGGNGTNATGMGNACNATHGTNAAYGAYTGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TGGYTNCAYTGYAAYGGNTGYTAYTGYCARCCNGARCCNGGNGARYTNMGNTTYCAYATH ACNAAYTGYAGYCAYATHTAYTGYGARAARTGYGTNACNGARTGYACNAARGARMGNTGY AARGTNTGYCARTCNCARTGYGCNAGYYTNGARYTNTCNGGNAARYTNCARAARGARGTN GARAAYYTNTTYGAYGARCCNAGYAAYATHYTNGARAARGCNGTNAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGATHYTNTAY CARTGYATHATHTCNGGNGAYGARATGTTYACNGAYACNTAYAAYATHGARGARAARGAY GGNTTYTAYGTNYTNAARGGNAARTTYATHACNAARAAR---GCNGAYGAYGTNGAYGAR TCNYTNYTNGGNGCNAAYCCNAGYGCNGARGARGCNTCNGAY---GAYGTNGARGGNAGY GTNGARTCNGGNGTNGAYGTNATHATHAAYAAYMGNYTNAARGARACNGGNTTYGGNGGN AARAARGAYTAYCARGTNTAYATGAARGARTAYATGAARACNGTNTTYGCNAARYTNGCN TCNAARATGTCNGCNGARGAYGTNGCNAARGCNAARGCNGARGCNACNGARGCNTTYAAR CARGCNGTNAGYAARTTYAARGAYTGGCARTAYTAYACNGGNGARAGYCARAAYCCNGAY GGNCAYATHGCNYTNATHGARTGGYTNGAYGARAARGTNGAYGGNAARGAYGTNCARACN CCNTAYTGYTAYTTYTAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ACNTAYMGNAAR TTYTAYGGNMGNMGNCCNGAYGGNYTNAAYGGNGCNATG--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNCCNMGNCAYGCNMGNGARTAYGAYGGNGCNGAYAGYTCNGAYYTNGAR GARAARGAYCCNGAYGGNAAYATHTCNGAYGARGAYACNGCNGAYGCNAGYGARACNGAR GAYAARAAR---TCNCAYAARCARAGYYTNCCNCCNAAY---GGNAAYCARMGNACNGAR ATHAARGARCARATGTAYCARGAYAARYTNGCNCARATHAARAARCAYATHCARATGYTN GARGARGGNACNYTNCARGARTTYYTNAARMGNACNAARNNNATHGARYTNAAYTAYMGN GARMGNYTNMGNGAYAAYGARATHTGYAARAARGTNGAYATHGARAARGCNGARCARAAY TAYYTNGTNGAYTGYGARAAYGCNCARAARGARTTYGARGARAARMGNGTNGCNATGAAR GARAGYYTNATHAAYCAYATGAARGARAARAARGTNGAYYTNAARGARACNYTNGTNGTN GAYYTNAARGARAARMGNAGYGTNATHGARYTNGARMGNCARGTNYTNGAYYTNAAYGGN GCNGAYTTYATGGARGTNAARCCNACNATGACNMGNAARYTNMGNMGNMGNCCNAAYGAY CCNATHCCNATHCCNGARAARMGNMGNAARCCNTCNCCNGCNCARGTNAAYATHYTNYTN GAYGAYGAYYTNATHYTNGCNGAYYTNMGNYTNATHATGAARGTNAGYGGNAARCCNATH GCNAARAARCARGGNYTNGGNACNCAYAGYCCNYTNATHGAYACNTCNTCNGAYGTNMGN ATHGARGAYGGNMGNYTNTGGTAYGAYAARAARTGGTTYCARMGNAAYACNATGGTNCAR ATHGAYAAYAARGARACNGGNTCNMGNATHCAYGGNACNATHACNAAYATHYTNAAYCAR GARATHTGGGTNAARAARGGNGGNGAYAAYTCNAARYTNMGNATHTGYYTNAAYCARTTY CARAARGGNAARTAYAAYATGAARAARMGNACNACNACNYTNGGNMGNACNGAYTAYCCN TCNGGNATGAARCARATHGTNYTNAGYTTYTTYACNAARYTNYTNTCNMGNATHGCNCAY CCNYTNYTNCCNCAYATHAAYGTNCAYMGNGCNGTNCARMGNATGGTNAARACNTGYGGN GARACNMGNGCN------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTCNMGNGCNGTNGCNTCNAARACN MGNGGNGCNGAYAARACNAARCCNCCNGCNTCNCARACNCCNGTNATHGCNCAYGARATH GTNCCNGGNAARTTYAAYGAYAAYGAYTGGAAYGTNATGYTNGARMGNGAYGGNGGNGAY GARTTYGTNATGGAYGTNATGGAYGARYTNATGGARAARACNATGGCNTCNATHTAYGAY AARTAYATHGARMGNCARYTNYTNCCNTTYACNATHACNCARGCNMGNGAYGCNATHATH GARATHATHGARTGGCARTTYYTNACNMGNGAYGARGGNGARGARAARYTNGARGCNGAY YTNGGNTGGACNCARGAYGARGARCCNGARCCNGCNGARACNGAYTGYTGGGCNCARGGN TCNGTNCCNMGNAAYGTNATHYTNGCNCCNACNCCN------GAR---YTNCCNGARATH CCNGARGARGCNGARGARGTNTCNCARCARCARGARGARGARAAYGARACNCAR---GAR GARGCNGCNGCNCARGARCCNCCNGARYTNGARGAYGTNGTNTCNGARCCNGARGARTCN GARACNCAYTCNGARAARGARGARAARGARATHTCNAARGCNCCNTCN---------CCN CCNAARGTNTCNACNTCNAAYTCNAARAARAARTTYMGNCCNTAYMGNGGNAARYTNAAR TCNGCNGGNATHAGYAARATGACNGARTCNYTNGAYGAYACNGARATHAARATGATHTAY GAYGARATHTCNGCNTCNATGCCNCCNAAYGARGARAARCCNAGYACNYTNYTNAAYATG CCNGCNTCNTGYACNAGYATHYTNAARGTNCARACNGGNMGNCCNCCNGGNAAYAARGAY GTNGTNTAYGAYGARYTNGGNAAYGTNGTNGCNGTNATGAARYTNGAYCCNGARAARYTN CCNACNCAYAARGTNAAYGTNAARTAYCAYGTNGTNGAYCCNGCNGTNGARGCNGCNCAR GCNMGNYTNGAYGCNATGMGNAARGGNAARTCNACNGGNAGYAARATGMGNAARYTNAAR TCNAAYAARACNGTNGARGCNACNAGYCARACNGGNGCNGCNAARGCNAARGCNTCNCAY CARTCNAAYACNGTNGCNCCNYTNCCNCCNCCNYTN------------------------ ---------------------------------ATHGARGARATGGARGTNTCNCAYGGN GTNATHGTNMGNGARGGNGGNMGNGTNAARAARGGNCCNGGNMGNTAYTAYMGNAARYTN GAYGTNYTNGARGARAAYCARAARGGNATGAARCARGTNAGYGTNMGNATHAARAAYGCN GGNATHACNGTNAAYGAYYTNYTNGAYMGNAAYACNCCNATHYTNMGNCCNTTYGCNGAR CARTCNCCNYTNCCNCCNATHATHCCNCARCCNCCNCCNCARYTNCAR---CAR------ ------------------------------------------------------------ ---------------------------------------------TTYGARGARGARYTN GTNAGYTAYGGNGCNGGNGGNAGYTTYMGNCCNGARYTNGGNAARYTNGTNAARGGNGAY AAYGCNGAYATGATHGARMGNTGYATHMGNGAYTCNTGGGAYCAYTAYACNAARYTNGCN ACNTCNGARCAYGCNAARGAYTCNGGNCARTCNATGGTNTTYACNYTNGCNTCNCAYCAR AARCCNAARGAYGCNGAYTAYGCNGTNYTNMGNGAYYTNACNTGGGAYTTYMGNYTNYTN TCNGARACNGARATHMGNCARMGNGGNATHCCNAARGARTTYAARTAYACNTAYGGNTTY ACNACNGTNATHTCNCARGTNAAYATHTAYYTNCCNTGGYTNAARAARCARTTYATHGCN AARGGNGGNAARATHCARAARMGNACNGTNAAYAARYTNGARGARYTNTAYGGNGARTAY CARYTNGTNATHAAYTGYTGYGGNGAYMGNGCNMGNACNTTYGTNGGNGAYGARGARTCN TTYCCNACNMGNGGNCARYTNGTNMGNGTNAARGCNCCNTGGTTYAARCAYTCNCAYTAY TTYGAYACNGAYAAYTAYATGATHCCNCAYTCNGAYAARYTNAAYATHGGNGGNATHMGN ATHCAYGGNGAYGGNAAYMGNAARATHGARCCNGARGTNACNGTNGAYATHATGAARMGN GCNGARGCNYTNTAYCCNCARYTNAARGGNGCNGARMGNATHGGNGARTGGGCNCAYTCN MGNCCNGGNMGNACNMGNCCNMGNATHGARAARGARGTNYTNAAYYTNGGNGGNAAYMGN MGNYTNCCNGTNATHCAYAAYTAYGGNCAYGGNGGNAAYGGNATHACNYTNAGYTGGGGN TGYGGNAARTAYGTNGCNGARYTNGCNAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYGTNGARGCNGCNGAYMGNGGNATHCARTTYTTYATG GGNTGGTAYGCNCAYCCNATHYTNGTN---GAYGGNGAYTAYCCNCARGTNATGAARGAY TAYGTN---AARAAYGCNACNTCNCCNTTYYTNACNAARTCNMGNYTNCCNGARTTYACN GAYTAYGARAARGCNMGNATHGCNAARACNGCNGAYTTYYTNGGNYTNAAYCAYTAYACN TCNGTNYTNGCNGAR---------GARGGNGTNAGYGGNGAYGGNTAYTTYGGNGAYMGN GAYATHYTNGAYTCNAARGAYCCNAGYTGGYTNACNTCNGGNTCNGTNTGGYTNMGNTCN AAYCCNATHGGNATHMGNAARAAYYTNAAYTGGATHMGNCAYCARTTYGGNGAYATHCCN ATHTAYATHACNGARAAYGGNGTNTCNGAYAAYAGYACNYTNGAYGAYGAYTAYMGNGTN GGNTAYTAYCARAGYTAYATHAAYGARGTNYTNAARGCNATHMGNYTNGAYGGNATHGAY GTNMGNGGNTAYACNGGNTGGTCNYTNATGGAYAAYTTYGARTGGGCNMGNGGNTAYTCN GARAARTTYGGNGTNTAYYTNGTNGAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARGARGGNMGNGARATGGGNGGNATHATHATHATHYTN GCNTGGACNGGNATHTCNMGNTTYTCNCCNTTYAARAGYTCNMGNTCNGGNTCNTCNACN AAYYTNATGACNGGNYTNYTNGTNGTNTCNYTNACNYTNGCNGTNGTNCCNYTNGTNACN TGGTCNYTNTGYTTYGTNGGNGAYTGGCAYAARMGNYTNGGNCAYTGYTCNGGNATGTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CCNTTYGAYTCNTGG GARGAYYTNTGYGTNAARTTYGAYAGYAAYAARCCNYTNTCNACNGCNYTNATHTCNGGN TGYAARGARATHATGMGNGTNMGNAAYATHATHMGNMGNYTNATGGTNMGNTGYGARAGY ATGTCNCARCARATGGARAARGTNGTNGCNACNYTNAAYGARAGYCARAAYAGY------ ------GAYAAYGGNMGNATHGTNMGNCARCCNGGNYTNYTNAAYAGYAAYTTYTCNYTN AARCCNTAYCARYTNATHGGNYTNAGYTGGYTNMGNYTNATGCAYGARCARGARYTNAAY GGNATHYTNGCNGAYGARATGGGNYTNGGNAARACNATHCARGCNATHTCNTTYYTNGCN CAYYTNYTNGARGARGAYGARGARGGNCCNCAYGTNATHATHGTNCCNTCNTCNACNATH GARAAYTGGYTNMGNGARYTNCARACNTGGTGYCCNGCNYTNAARGTNATHGTNTAYTAY GGNTCNCARGARGARMGNMGNGCNGTNMGNCAYTCNATHTTYGTNGARCARGARGARTTY AAYGTNYTNYTNACNACNTAYAAYATGGCNACNGGNGGNGTNGARGAYMGNGTNYTNTTY AARAARTTYGARTTYCAYTAYGCNATHTTYGAYGARGGNCAYATGYTNAARAAYATGTCN TCNYTNMGNTTYCARAAYYTNATGAARATHGTNGCNGARMGNMGNYTNYTNYTNACNGGN ACNCCNYTNCARAAYAAYYTNYTNGARYTNATGTCNYTNYTNTGYTTYGTNATGCCNGAR ATHTTYCARGGNAARACNGAYCCNYTNAARAARATGTTYACNATGATHTCNMGNTCNGAR GAYAAYAARAARAGYMGNTTYGARTCNGARMGNATHGCNCARGCNAARMGNATHATGAAR CCNTTYATHYTNMGNMGNYTNAARAARGAYGTNYTNAGYCARYTNCCNAARAARACNGAR AARATHATHACNTGYMGNYTNACNGARACNCARAARMGNYTNTAYGAYGGNYTNGTNTCN AARTAYGCNYTNGARGTNGARAARTCNAAYGARGARTCNTCNAAYGGNAGYGTNGGNGTN TTYATGCARTTYMGNAARGCNGCNAAYCAYCCNYTNYTNGTNMGNAAYYTNTAYACNGAY GAYATHYTNGARCARATGTCNAARAARATHGCNMGNGARCCNACNCAYMGNGAYMGNGGN GCNYTNCCNAARYTNATHCARGARGAYATGTCNTAYATGAAYGAYTTYGARYTNATHGGN YTNTGYAARCARTAYAARAARTAYYTNGGNAARTTYGARYTNGAYCCNTCNGTNATHGAR GAYTCNGGNAARTTYAARAARYTNGAYGARYTNYTNCCNTCNATGAARGARMGNGGNGAY MGNGTNYTNYTNTTYAGYCARTTYACNATGYTNYTNGAYGTNGCNGARCAYTAYYTNGAR AARMGNCARCAYAARTTYATHMGNYTNGAYGGNCARACNCCNGTNCCNGAYMGNYTNCAR YTNATHGAYMGNTTYAAYAAYGARCCNGAYATHTTYATHTTYYTNYTNTCNACNMGNGCN GGNGGNYTNGGNATHAAYYTNGTNACNGCNAAYACNATHATHYTNCAYGAYATHGAYTTY AAYCCNTAYAAYGAYAARCARGCNGARGAYMGNTGYCAYMGNYTNGGNCARAARMGNGAR GTNAAYGTNATHMGNYTNATHTGYGARGAYACNGTNGAYGARTCNATGYTNMGNTGYGCN AAYAGYAARYTNGCNYTNGARAARGAYYTNACNGGNGCNGGNGARGARGARAGYGARGAR GGNACNAARGAYGTNGCNAAYYTNYTNAARGARGTNYTNAARCARMGNCARAARAGYAAR AAYGAYTAYAAYATHGGNATHYTNGAYGTNAARAARCCNYTNGAYTGYAGYTGYCARGAR YTNYTNTCNATGCCNAAYATHGTNATGAGYGGNTGGYTNMGNAARMGNGCNYTNMGNAAY AAR------TTYATHACNATGAAYTGGCCNAARGARTAYGTNATHGTNGCNAAYMGNTCN YTNTAYTAYTTYTCNAGYGARACNGCNAARAARGCNTCNGGNTCNTTYTCNYTNTAYGGN TTYAAYMGNATHMGNMGNGARCAYGGNYTNAARGTNAARGAYAARGTNTGGGCNTTYAAR YTNGARCAYATHCARCCNACNATHMGNTCNYTNTAYTTYTCNGCNTCNTCNGARAARGAR ATGGTNATHTGGATGMGNGCNATHAARAARGARATGYTNCARGCNAAYGGNAARACNTCN TAYAGYACNGCNGCNGAYTCNCARTAYGGNGARTCNATHGCNTCNGARGAYTCNTGGGGN TCNTCNGAYTAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TGYGTNMGNCARTAYYTNMGNTGYGARGAYACNGTNTGGAAYMGNGCNATHTGY GTNGGNGGNTAYTTYAAYAGYACNATGAARGARTGYGTNCCNGCNGAYGAYCAYTGYCAR CARMGNAGYMGNMGNCARGCNACNACNAGYTGYGAYCARTCNTAYAGYTGYCCNGARGAY YTNATHCARGARTTYATHTAYCCNGAYTGGMGNGAYTGYGAYACNTAYTAYAARTGYYTN AARGGNGTNYTNAARYTNCAYTCNTGYGARAGYGGNATHTAYAARTAYTAYAAYCCNMGN ACNTTYAGYTGYGARGARTAYCCNTCNGTNACNAAYACNTGYYTNMGNMGNTAYGARACN ------------------------------------------------------------ ------------------------------------------ATGGCNGAYTCNAARTCN AGYYTNGCNMGNGAYGGNACNATGCARGTNACNGCNAARGARGGNATHGAYTAYYTNAAR GCNGCNAAYMGNGAYACNYTNYTNAARGCNCARGGNYTNATHAARGAYAARCCNGCNGTN CARMGNGAYGGNACNATGGTNTCNACNGCNAARGARGCNGARMGNYTNYTNGAYGGNAAY AARCCNGAYGCNGAYGCNCARACNMGNGGNCARCARAARCARATHGARGAYYTNAARACN GCN---GARGCNCCNAARGCNAARAARGCNMGNYTNGCNAARGAYGGNACNATGGCNGTN ACNGCNAARGARGCNAARGCNYTNYTNGCNGGNGARAARYTNGGNGAYACNMGNCARGAR ACNAARTCNAAR------CCNGTNAARACNCCNYTNAARAARGCNAAYACNATGGCNMGN ACNGTNGARGARGCNAARAGYGTNYTNGAYGGNAARGTNGAYYTNAGYGARGGNMGNAAR ACNMGNTCNCARAGYMGNGGNGARGCNCCNAARCCNTCNATHAARAARCARGGNACNATG CARCARACNGCNAARGAYGGNAARGCNTTYYTNAARMGNTCNAARGGNAARAAR------ ---MGNGCNGCNAARGCNGAYGAYGAYGARYTNTCNGAYTAYGARGAYGTNAAYTAYCAR GAYYTNCCNGCNGAYGARGGNTGYTGGYTNTAYACNCCNTCNAAYTCNAAYAGYTGYTCN TGGTCNGARGARGARYTNATHTCNTGGATHMGNCARGAYTTYGAYCAYCCNACNCCNGAR MGNGARTCNTCNAARMGNGCNYTNATHCAYTTYATHGARGARGCNTCNMGNATGAARCCN TCNAGYMGNYTNGCNYTNGAYACNAAYACNTTYACNMGNCCNAARMGNCCNGCNGTNTCN GCNGGNCCNYTNCAYGGNGARGGNGAYCARGCNCAYAAYGTNCCNAAYGCNGCNGAYATH GARAAYYTNGCNAARCARCARGARGARAGYYTNMGNCARAGYGTNACNCCNGCNAARAAY ACNYTNMGNAGYAARCAYCCNYTNATHGARGGNGAYAAYGGNGCNMGNACNAGYCCNAGY MGNTTYGAYGCNGARGGNTCNTAYATGACNCARCAYMGNGGNAGYTTYAGYTCNGAYCCN AGYACNCCNCCNGAYAGYCCNCAYAAYAGYCARCAYTTYCARYTNAAYCCNAAYAAYGAY GGNMGNGTNMGNMGNACNYTNCCNACNGGNTCNGGNYTNCARTAYMGNTCNCAYAAYTCN AGYGAYTCNAGYYTNGARMGNCAYAGYGTNGAYACNAAYGGNAGYGAYGARGCNAAYYTN GCNCCNGARGCNATGMGNGCNCCNTCNTCNMGNYTNCARCCNCCNMGNAAYAARAGYACN TCNTCNCCNAARMGNGGNTTYTCNGGNYTNGCNCCNGGNYTNGCNAARCCNCARCARMGN GGNGTNTCNCCNCARMGNCARACNGGNYTNCCNACNCCNMGNMGNCARATHGCNMGNCCN TCNACNGCNCCNMGNTCNTCNYTNCCNCARTTYMGNMGNCCNGTNACNCCNTCNTCNGGN GGNCCNAAYCARTCNCARGARGCNAGYTGGMGNGARGGNTGYTTYATGCCNAGYYTNCCN YTNATH---------------------AARCAYACNATGGCNGCNGCNGGNGCNAGYACN GCN------------MGNGCNATHMGNCCNCAYGTNCCNTCNATHMGNTTYCCNAARMGN GARCCNYTNAGYGARATGCAR------GCNMGNCCNATHGGNAAYCCNAAYTCNATHGAY GCNYTNATHACNAARAAYGTNACNTCNGGNCARTCNGCNCCNGCNTCNAGYGGNTCNACN GCNAARGGNCCNTCNATHGAYTCNTCNGARGTNCCNACNMGNTTYCARMGNAARCCNYTN TCNAAYGARGARATHGARTAYATHGARAARGGNGGNCCNGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGNCCNGCNCCNGARGAYCCNAARCAYATGGAYTCNATHCCNGGNGAR GTNGTNYTNTGGACNAAYCAYMGNGTNATGGARTGGYTNMGNACNATHGAYYTNTCNGAR TAYGCNCCNAAYYTNMGNGGNAGYGGNGTNCAYGGNGCNYTNATGATHYTNGARCCNMGN TTYAAYGCNGARYTNTTYGCNGTNYTNYTNTCNATHCCNGCNAGYAARACNYTNYTNMGN MGNCAYYTNAAYTCNCAYTTYATHGGNYTNATHGGNGCNGARACNCARCARMGNAARMGN GARYTNGARTCNACNTCNGGNTTYACNCCNYTNYTNCAYAAYAAYAARATHAARAARGGN AARTTYGGNYTNTTYAAYCAYAARMGNAGYMGNTCNGARCCNGARATGGAYAGYYTNATH TGYCCNCCNGAYYTNAAYGGNTAYACNCAYATHCAYACNCARGCNTCNCCNYTNYTNTTY CAYGCNTCNGARAARYTNTGYGGNATGCCNATGAARMGNMGNAARGCNATGGAYCCNCAR ATHGCNGTNGCNMGNACNCARAARMGNATHAARAARATHGAYAARGARATHAARMGNYTN TCNMGNGTNGGNAARATHYTNAARCCNGTNGARGARATHGAR---GTNGAYAARMGNATH YTNATGGCNCCNGARMGNMGNMGNGCNTCNACNGTNYTNAGYTTYGAYGARTCNGARTCN MGNGCNTCNYTNCAYAARMGNTGGTCNGTNTAYMGNACNAAYMGNTAYGTNGARATGGTN TCNGTNTTYTCNAARGTNGTNGARGCNCARCARGARGCNYTNGAYGARYTNMGNGCNGAR TCNGARGARYTNTAYCARGCNGCNATHCARAARGAYGARAGYYTNYTNCCNYTNACNTTY TCNGGNCCNAARGARACNCCNCCNATHAARAAYTAYACNCCNCCNGAYGGNGARTAYGTN GAYACNACNMGNAARTTY---------AGYGGNGARATGGARTGGAAYATHGAYATGGAR GTNAAYYTNTTYCAYGCNATGMGNGGNCAYAARCCNGCNGGNGTNAAYMGNCAYTTYCAR ATGATHGCNATHCAYGAYAARTTYAGYTCNTCNACNAARAARGTNACNTCNAAYGAYGTN TGGAARCAYYTNTCNACNYTNTAYGAYYTNCARGCNYTNTAYGARTCNGARATHGTNCCN TTYCCNAAYAARAAYGGNGAYTTYGCNYTNGTNGAYAARGAYATGYTNGAYYTNTGYACN AARTCNTTYCCNMGNTCNTCNTAYATHAAYAGY---------GARCCNGCNAARCCNGAR GCNCCNGGNAARAAYATHTCNAARTTYAGYACNAARCARGAYGGNAARATHGGNTCNCAY ACNCCNAARACNGARTCNAARAGYGARCAYAAR---TCNTCNAGYGCNTCNAARTCNGAY AGYMGNTCNAAYACNCCNTCNAGYMGNTCNGARTCNAARTCNTCNCAYCAYCAYAGYAGY AGYAGYGGN---CAYAGYAGYTCNAARTCNTCNCAYCARAGYACNCCNACNTCNATHCCN TCNCCNTCNCCNAARMGNGCNAARMGNACNMGNAAYGTNAAYTCNGCNTCNGCNAGYCCN GCNACNCCNACNGARCCNCARTCNAARMGNMGNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARGAYGAYGCNATHGAYGTN AARGCNYTNCARGAYMGNYTNAARCARTCNGARATGMGNYTNYTNGAYTTYMGNAAYCAR TGYCARCARYTNMGNCARGARYTNAARGTNGCNCAYAARGTNATGTCNCARGARATHGGN GARACNGTNAAYATHCARTCNYTNYTNAAYGARACNAGYCARTGGMGNGGNMGNGCNCAR CARATHATHGGNYTNCARCARGARGTNGAYGARYTNAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TAYGAYTTYGAYTTYTGYYTNCCNGTNGGNGTNGAYAARGAYCARGAYGAR TTYACNATHCAYAARGGNTGGATHGCNGGNGCNTTYTTYYTNGGNYTNYTNATHGGNGTN GGNATHGTNYTNYTNYTNGCNMGNCCNTTYYTNAAYTCNTGGGARAARAARAARMGNCAR GAYGARGARTAYATGYTNGARACNGTNAARGCNGARYTNGCNGARGARAARGGNAARAAR GGNMGNMGNAARTCNAARGCNGTNAARGARAARGARATHAARGTNGGNGCNATHMGNACN AAR------------------TCNMGNTTYTGGMGNMGNAARCCNAARGGNGGNGGNAAR GAYGAYGTNGTNAARGARGGNGAYGTNGAYCCNGCNCAYGCNMGNGGNATGGTNGAYGTN ATGYTNCAYACNACNAGYACNGGNGARGAYGTNGARYTNGCNGAYCARGAYATGGCNTCN ATHATHTCNATGGARMGNGGNYTNGARGARGARAARACNACNYTNATGYTNAARACNYTN GCNATHYTNYTNMGNAARAARGCNGARAARMGNGARATHACNCARAAYTTYTAYACNGAY TTYATGAARAARACNGARGARGAYYTNAARGAYATGGGNACNATGATHGAYMGNGARAAR GARGARGCNGARGARAARYTNAARAAYGAYCCNAARYTNAGYAARGAYACNCARACNATG GARACNGARATGCARAARYTNCARACNCARTTYAAYCAYAARCARGCNMGNYTNCARAAR GAYTTYMGNGAYAARATHMGNYTNGAYYTNYTNMGNTCNTCNGGNATGCCNGARTCNGAR GTNGARGARGTNATHTCNGGNYTNATGGGNAAYATGGCNCAYGTNGARGARAARYTNGGN YTNGARCARGCNMGNCARMGNMGNTCNTTYGARGARMGNYTNGCNAARMGNMGNCARGCN ATGGARTAYCARCARATHGAYAARGARGARAARGCNAARGARCARGARGARMGNGTNAAR GTNTTYMGNTCNYTNYTNGARCAYCAYACNAARGAYGGNTCNYTNYTNGARAARCARTGY GAYAGYATHGTNTCNGAYTAYGGNAAYGARYTNGAYCARYTNAARAARTAYAAYGCNGAR GARTTYAAYCARYTNMGNYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGAYATHYTNTAYTTYTCNYTNTGYTTYATHGCNYTNTTYGCNTCNTCNTTYGGNCAR GAYCCNCCNYTNGCN---GTNACNTTYGARAAYATGACNMGNGTNGAYGCNGTNGARGGN ACNGARATGGTNTAYTTYAARTGYCAYGTNAAYMGNGGNGCNATGTTYGTNYTNMGNAAY AARGTNGARATHATHCAYATHCAYCCNYTNACNAARGAR------------------GAR ACNATHYTNAGYTCNGCNGGNGAYYTNCARGARGGNAARCCNGCNTTYTAYGAYGTN--- AARATHGAYAGYCAYCCNGAYAARMGNGAYCAYATGGTNGTNTTYATHATHAARAARGTN MGNTAYCARGAYGAYGGNATHTTYAARTGYCAYGTNCAYTCNGGNGGNAARGGNGAYTCN TCN------------------GARGAYGCNTTYATHGARMGNGARGTN---GTNGTNCAY MGNCCNTTYTCNTCNYTNACNYTNAARATHGGNGAYTTYGAYCCNYTNACNGARTCNCCN TTYTTYATHGAYCAYGGNAAYTAYAARGTNGCNTGYATHGCNGARGGNAGYAAYCCNTCN ACNGARGARATHCAYYTNTAYTTYGAYGGNAAYCCNYTN---GARCAYAGYGARAAYTTY ATHACNGCNATGAGYGGNCCNGAYMGNATGTTYAARACNGARATHAAYGGNACNYTNAAY YTNGTNGTNAGYAAYTCNGGNAARAARYTNGTNTGY------CARGCNGARGAYTCNACN GGNCARTCNAARACNGTNTTYYTNATHCCNGAYATHAAYGTNTAYGAYCCNGTNGTNTTY TGYAAYGAYACNGARGCNCAYATHGGNCARGAYAAYCCNACNATHATHTGYACNGTNAAY TAYACNGAYCARGARGTNGAYGGNTAYTCNTAYCARATHGGNGAYAGYGGNMGNATHTTY AARGARGGNGAYCARAAYGAR---------GAYAAYGTNGTNGTNTCNGTNTCNAAYGTN GCNCCNGGNGTNTCNGTNGTNGCNYTNGAYYTNCAYAARGCNCARGARATGTAYYTNGAY AARGAYTAYTAYYTNYTNATHGAYYTNGTNGGNGGNCAYTCNGTNMGNGARAARGTNMGN YTNTCNAARAARGARGCNCCNGTNACNGAYAARGGNAAYAAYGAYGGNGGNAAYCARGGN GGNGARATH--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------AAYGGNGARYTNMGNMGN MGNAGYAGYCARACNTCNACNCAYAGYGAYCARYTNCCNTTYGCNGTNATHAAYMGNAAY GTNATGMGNMGNGAYTCNTTYGARATGCCNCARMGNACNATHATHGAYTCNCCNMGNCCN ACNMGNTCNMGNTCNYTNCAYAARTCNCCNGTNGARGCNGCNGCNATGCCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GGNGCNCCNGGNYTNTCNGAYGCNTAYGTNGCNGGNTTYYTNTGGYTNGAYAARYTNGGN YTNGCNGCNAARTAYGGNGTNACNMGNGTNTTYMGNCARACNTTYTAYGGNGGNCAYTAY GCNYTNYTNTCNCCNACNYTNGAYCCNAAYCCNGAYTAYTTYYTNTCNYTNYTNCAYAAR MGNYTNATHGARGGNCCNGTNTTYAAYGCNACNGTNCARCCNAGYATGCCNCARYTNMGN ATHTAYGCNCAYTGY---ACNMGNAAYYTNGGNATGTAYAARAARGGNGCNATHACNYTN GCNTAYYTNAAYACNAARAAYGAYTCNACNACNGTNAGYYTNCCNCARTTYGCNACNYTN CAYTTYGAYYTNTAYATHYTNACNCCNGGNGAYTCNGCNGGNYTNAARTCNAARGTNGTN AARYTNAAYGGNGARGTNYTNAARATGTCNGGNTCNTCNYTNCCNTCNYTNAAYCCNAAR YTNTGGAARGGNGAYATHGTNYTNCCNCCNYTNTCNTTYGGNTTYATHGTNGTNCCNGAY GCNAARGTNTCNYTNTGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNCCNCCNMGNAARATHYTNGTNGCNGGNGTNGARCAYGAYATHAGYTTY CARTTYCCNCCNMGNACNATHYTNATHGAYGGNAARCCNTGYGARYTNAARYTNGAYAGY AARATHCCNTAYGTNGTNATHGARGGNAARCCNCAYGGNATHMGNTTYGARGGNGARCCN MGNACNATHTTYATHAAYGAYCARCCNTTYATHATHCCNYTNGAYAARGCNGARAARATH MGNATHGGNCARMGNCCNACNTAYATHGCNTTYGGNGGNCCNGCNCAYGARATHATHATH GAYGGNAARTGGTTYGARGTNAARTTYGAYAAYACNATHAARGAYATHCAYYTNGGNAAY MGNCAYTTYMGNATHMGNATHCCNGGNCCNYTNCCNMGNGTNAARATHYTNGAYCARYTN CCNATGAAYTTYGAYGTNTCNAGYYTNATGATGAARAAYTCNATGGARGTNCARMGNCAR ATGCCNTCNACNGTNYTNMGNCCNGCNGGNGTNGGNCCNCARMGNCCNGGNCARATGCAR YTNAAYCCNYTNGGNCCNGGNCCNAAYACNGGNCARATHAARAAY---ATHCARCARGCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TGYGGNAARACNTTYAGYMGNAARTTYGTNYTNGAY GGNCAYATHAARACNCAYACNGGNGARAARCCNTAYTCNTGYTTYGARTGYGGNTCNGCN TTYTCNCARAARAGYAAYYTNYTNMGNCAYATHAARACNCAYACNGGNGARAARCARTAY GARTGYCAYACNTGYGGNMGNACNTTYTCNACNAAYTAYGTNYTNAARMGNCAYATHAAR GTNCAYACNGGNGARAARCCNCAYTGYTGYYTNACNTGYGGNAARACNTTYCCNMGNAAR AGYACNYTNGAYATHCAYATHMGNAAYCAYACNGGNGARACNCCNTAYGCNTGYACNGAY TGYGGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GARGAYGAYGARGAY GAYGTNGAYGARTTYACNGARGAYGARATHGCNAAYGAYCCNTCNAARMGNATHYTNTGG GCNTCNGARAAYAAYAARATHGARATHGTNGARGARYTNGTNAARGARGAYCCNGGNYTN GTNTCNGTNTGYGAYGGNGAYGGNTAYACNCCNYTNCAYMGNTGYTCNTAYAAYAAYCAY CCNGAYGTNGCNAARATHYTNYTNTCNTAYCAYGCNAGYGTNAGYGCNAARACNGTNGAY GGNTGGCARCCNYTNCAYAGYGCNGCNMGNTGGAAYTCNGTNGARACNGCNCARATHYTN ATHCAYAAYGGNGCNGAYGTNAAYGCNCARACNAAYGGNTGYYTNACNCCNYTNCAYATG GCNGCNTCNGAR---AGYAAYGGNGARATGYTNGARYTNYTNYTNCAYAAYCCNTTYATH GAYATHAGYATHGTNTCNAARGGNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNYTNTCNYTNGAYTCN GTNYTNGTNYTNYTNCARAGYCARAAYCARTCNGARATHCAYYTNAAYTCNCAYGTNAAR CARGTNYTNGARYTNATHYTNACNGAYACNAARMGNAAYAAYGTNTTYGARGARGCNGTN AAYYTNYTNTGYGARATHTAYATHTCNYTNYTNAARGARAARMGNTCNAAYTCNTCNCAR YTNAAYCARAAYTCNCARACNAARYTNTCNGCNYTNCARGGNAAYGGNCAYTTYGCNATH MGNTAYGGNTGGYTNGAYGARYTNCCNCCNTTYTAYGGNGCNGARGARATGYTNMGNCCN TGYCARAAYYTNGARGTNAARMGNGCNTTYGGNCARGGNCCNMGNGGNGCNACNYTNTCN TCNAAYTCNYTNGTNAAYCCNGAYGARAARGGNCARTGYCCNTGYYTNYTNTGYAAYGGN AAYYTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARACNACNTTYCARCCNGAYAARCARGARYTNGARAAYAAYTTYGTNYTN TTYGCNTTYTGYACNTTYATGAGYATGGCNGAYGTNAGYYTNGAYGTNCARAARATHGAY ACNMGNGCNCARTAYMGNTGYMGNTGYMGNGCNAARAARGGNGTNAGYTAYAARACNTGY ACNYTNCAYTAYTGGYTNTGYCCNMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARGARACNAARGARCARATHATGAARMGNYTNCCNAARMGNYTNYTNTAYYTNYTNMGN TAYGGNGCNGTNAARGARGGNYTNGARGTNGAYGAYAAYGGNTTYGTNGAYGTNGARCAR GTNATGACNGTNCCNYTNYTNAGYGARTAYTCNCAYGAYGARYTNATGAAYGARGTNAAR ACNTCNGTNTCNTAYMGNGAYACNCAYMGNTAYGARTGGAARGARAARGAYAARAARATH TTYATHMGNGCNACNTAYYTNMGNMGNTTYGARGCNAGYCCNGTNCAYCCNGGNACNMGN GTNAARACNYTNACNGARACNAGYATGATGTGYGTNYTNGAYAAYYTNGAYATGTTYGAY YTNGARGAYTTYCARGAYGARTAYACNATHAARYTNATGATHMGNMGNYTNATHMGNAAR AARGCNGTNACNAAYAARGCNYTNTCNGTNYTNYTNATHCCNACNATHACNMGNATHGAY ATGGARGGNATHTAYYTNACNAAYAAYACNYTNMGNATGYTNTGGACNCARTGYCCNCAY YTNATHGGNATHAAYYTNAARAAYTGYGGNTAYATHATHACNGAYACNATGYTNACNCAR YTNGCNAARAAYYTNCCNATGYTNGARCARYTNAAYYTNAGYMGNTGYGCNCAYYTNACN GAYAARTGYYTNGCNATHATGTCNAARMGNYTNYTNCAYYTNMGNGTNYTNCAYATHGCN GGNGTNCCNTCNATHAARCCNAARGTNGTNCAYACNTTYYTNGAYTCNGCNAARAARYTN ACNTTYYTNGAYGTNTTYTAYATGAARACNACNCARGARGARTTYGAYTCNYTNATGAAR AARGCNGARAGYYTNGAYGTNMGNYTNATHYTNCAYTCNCCNAARATGAARYTNCCNGTN AARGARGARTAYTTYTCNGARGARGAYGARGARGARGARGGNAAYGAR------ATGAAY GAYGARGARGAYGAYGAYGAYGAYCARTAYAAYGGNTGGACNGTNGTNCARAARMGNCAR GAYGGNAGYGTNGAYTTYTAYMGNGGNTGGGARGAYTAYMGNMGNGGNTTYGGNAGYYTN GARGGNGARTTYTGGYTNGGNAAYGAYAAYATHCAYTAYYTNACNAGYCARGARCCNACN ATGYTNMGNATHGARATGGARGAYTGGAAYGGNAAYTTYCAYTAYGCNGTNTAYGAYTAY TTYMGNGTNGARGGNYTNAARGAYAAYTAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNCCNTAYYTNGGNAGY AARATHAGYYTNATHTCNAARGCNGARATHMGNTAYGARGGNACNYTNTAYACNATHGAY CCNAAYGARGCNACNGTNGCNYTNGCNAARGTNMGNTCNTTYGGNACNGARGAYMGNCCN ACNGAYMGNCCNYTNCCNGCNMGNAAYGARGTNTTYGARTTYATHATHTTYMGNGGNCAY GAYATHAARGAYYTNCAYGTNTGYGARCCNCCNAARCAYTGYCAYACNGARGGNGGNGTN CCNCCNGAYCCNGCNATHGTNAARTCNTCNCARCCNCCNCCNGGNCCNGCNGGNGCNGCN TTYCAY------CCNGGNGCNGGNGGNTTYCARCCNGGNCARCARTAYCARCCNTTYACN CCNCARCCNATGTTYTAYGGNCARGGNGGNCARCCNGCNCCNGGNTAYCCNCCNCCNCAY CAYGGNCARCCNGGNTCNCARGARGARGTNTCNTCNATHGTNGARCARTCNCCNGARCAR AAYATHCAYGGNTCNATHGCNGCNATHGGNACNMGNCCNATHTCNGGNTCNCARACNTCN ACNCCNCCNYTNAGYMGNAARTCNCCNACNTCNGAYCARGGNGTNCARGTNCARCCNMGN AGYCCNGARAARTCNAGYAAYGARAGYATHCARCAYAGYCAYAAYTAYCAYAAYCARCAR AAYCAYCAYCAYCAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CAYTGYACNGAYYTNGARTGGGTNGARYTNTAYACNATHTGGGCNGAY YTNGAYAAYGAYGTNATHCARCARTTYACNAARAAYTGYCCNAARYTNMGNMGNYTNTTY YTNACNTGGTCNACNCAYYTNACNACNTGYGCNTTYGTNAAYACNYTNGCNTGYTCNAAY ATHACNCAYYTNGGNYTNGCNGAYMGNCARGARMGNGARCCNTAYYTNAAYTTYGTNYTN CCNAAYTTYCCNCAYYTNGTNTCNYTNGCNGTNAAYGGNMGNGAYATHCAYTCNGAYGAY TGYGTNGCNYTNAGYACNTTYTGYCCNAARYTNCARGARYTNGTNTTYGARYTNAARTCN ATGMGNGAYCAYGAYTGYYTNTTYGAYTTYTAYYTNCAYCARCAYAAYTCNYTNTCNGGN YTNAAYYTNCARCARATHGCNGARGCNTGYMGNCARYTNMGNAARYTNCAYGCNCCNTGY TCNMGNGTNGAYGAYGAYAGYATHGARAARYTNTCNYTNAAYTGYCCNTTYYTNGARGAY GTNAAYTTYATGCAYTGYCCNYTNYTNTCNGCNCARTCNYTNATGGCNYTNTCNGARAAY TGYCCNYTNATGAARTTYGCNAAYTTYCARCAYACNTTYAAYCCNCAYGAYTAYYTNCAR GARTTYYTNCARAARTGYMGNYTNYTNCARGARATHAAYTTYGAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYTAYCCNGCNGAYGTNGARGTNTCN TAYGAYGARTTYMGNTTYGTNGARCARATHYTNCCNAARAARATHGTNCCNGARATHCCN CAYCAYTCNTCNTAYCCNACNCCNTCNGGNTGGGTNCCNCCNAAYGAYGARYTNMGNTCN CARGARACNTAYYTNGTNMGNMGNACNAARAAYCAYGTNYTNCCNGTNTAYGCNGCNAAR ACNGARGCNTGGAARCARATHAARCAYCAYGTNATHATHAARAAYATHGARGGNGAYATH TGGAARYTNGARTCNGAYYTNMGNAARCAYYTNCARGARGTNACNCARAARAAYAARATH AAYACNCARGTNCAYGARGTNAGYMGNATHATHMGNATHMGNGGNGARYTNMGNGCNGAR ATHGCNACNTTYYTNATGGAYAARGGNATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNGARAARYTNGARTAY AARTTYAGYATHCARGGNMGNGARGAYATHGGNGTN---------TGYAARACNGARATH GTNATHAARGGNACNTCNGTNYTNTCNGGNYTNAARCARYTNGCNAAYAARGGNTTYATG AARTTYCCNYTNCCNMGNCAYYTNACNAGYGTNYTNGCNGAYCARMGNAAYAGYTTYTCN GTNGARATGGAYTGYYTNATHCCNYTNCARCAYCAYATHAGYAARYTNGTNYTNGTNGGN GAYCARGARCARYTNCCNGCNACNGTNYTNTCNCARGARGCNAARAAYTGYMGNTTYGAY TCNTCNYTNTTYCARMGNYTNCAYGAYAARTTYGARTGYAARGARGAYGTNTCNACNCCN GTNATGATGYTNAARGARCARTAYMGNATGCAYCCNGARATHYTNAARYTNCCNAAYTCN TAYTTYTAYMGNAAYYTNYTNACNACNCCNMGNCCNTGYATHAARYTNMGNACNTCNGAY YTNAGYCCNTAYYTNGTNTTYGAYATHYTNGAYGGNATHGARTCNTCNGGNAAYAGYGGN TCNAARTCNAAYAARAARGARGCNACNTGYGTNGCNYTNYTNTGYCARCAYGTNATHAGY YTN------ATGGCNACNAARAAYACNAAYTCNCARMGNCARAARAARATHGGNGTNATH TGYCCNTAYACNGAYCARAARMGNGCNATHMGNGAYAGYYTNGGNAARYTNGGNYTNTAY AAYATHGTNGTNAAYACNGTNGAYGGNTTYCARGGNCARGARAARGAYGTNATHATHYTN TCNTGYGTNMGNGCNCARGGNAAYCCNCARTCNGTNGGNTTYGTNGAYGAYAGYAARMGN ATGAAYGTNTCNYTNACNMGNGCNAARYTNGCNATGTAYATHGTNGGNCAYGGNAARACN YTNGGNACNTCNGAYYTNTGGAARYTNYTNTAYCARGAYGCNAARGAYMGNGGNYTNYTN GTNACNGTNCCNMGNACNGAYMGNTTYGCNGARATHGCNTCNAAR---------AARAAR MGNAARMGNACNTTYGARYTNGARGARCCNACNYTNAGYGGNGAYAGYACNCCNGTNATH GARAAYGAYCARCCNMGNMGNYTNMGNACNTCNMGNAAYAAYACNCCNCARAGYGARATH TCNGARAAYCARCCNGTN---AARMGNATGMGNMGNAGYACNTAYGAYAARTCNCCNTCN ATHCARGGNAARGAYAAR------------------------CAYTCNGAYGGNAGYCCN AGYACNMGNGCNATHYTNGAYTCNATHAAYGGNGAYTGYTCNAGYGCNGARMGNMGNGAR AARYTNYTNTCNGCNATHGAYAARAARGTNCARYTNAARATGGTNTCNAGYCCNTCNAAY CCNACNAARAAYCARCCNAGYCARATHCCNMGNTTYATGGCNTTYYTNACNAAYAARAAR AARGAYACNCARAAYTCNTCNACNCCNGGNAGYAARAGYTGGAAYAARATHCAYAARAAR GARTTYGCNAARTTYGAYTCNATHGAYGTNTAYYTNGARAARAARCARACNMGNAARGAR AAYYTNTCNGCNAGYACNAARAARCARYTNGCNAARCARTCNCCNGCNGTNAAYCCNTCN ---TCNMGNGCNGCNAARYTNCCNTCNATHGARCARGAYAGYTCNAARATHTTYAARCCN ACNGTNATGTCNGCNAARAAYATHAAYTTYGAYTTYTCNAARTCN---YTNTCNAAYTCN AGYAARATGCCNCCNTCNGTNAARGAYTCNTCNAARATHTTYGCNGTNACNGCNCCNAGY AAYACNCCNAARTCNMGNGCNGTNAAYACNCCNTCNMGNTCNACNAARAARGCNACNCAY ACNACNCCNTTYAARTTY---------ACNGGNAAYTCNAGYATGYTNAAYACNACNACN TCNTCNAARAARCAR---ACNTTYGAYYTNAARGCNAGYYTNGCNAARCCNYTNACNTGG AARCCNCAYACNGGNAARYTNCARTGYGTNGAYGTNAAY------GCNAARCCNAAYGCN CCNGTNTCNMGNTCNTCNGTNMGNAARGTNYTNAGYMGNGAYTCN------------GCN AAYAARAARMGNCCNGCNCARGCNAARAAYGTNMGNMGNGCNGCNCARYTNGAYMGNMGN AGYAAYCARAARTAYATHGAYATGATGAARMGNMGNGGNYTNATGGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNATGGARGARATGACNGAYATGCAR AARGGNMGNGTNMGNYTNGAYGTNGGNGGNCAYCARGTNACNCARGARGARGAYGGNACN ATHTTYATHGAYMGNGAYGGNACNCAYTTYMGNTAYATHYTNAAYTAYYTNMGNGAYGGN GGNGTNAAYCARGAYAGYYTNCCNMGNGAYMGNCARGTNYTNAARGARYTNATGCAYTTY GGNTCNAARTAYGTNTAYYTNGGNAAYGARCARGARGAYGARGARGARGTNAARGTNTCN ACNGTNGAYGAYGTNGTNYTNTCNGAYAGYGAYGTNAGYGAYGAYGAYGGNGARACNTGY YTNYTNGAYATHYTNGAYACNGCNGGNCARGARGARTAYTCNTCNYTNAARGAYCARTAY GTNMGNGAYGGNAAYGGNTTYGTNATHATHTAYAGYATHGTNGAYGCNGARAGYTTYAAR GARGCNGARGCNGTNTTYMGNTGGYTNAARMGNYTNMGNGAY---GARAAYTGYCAYGCN ATHYTNGTNGCNAAYAARCARGAYYTN------AARAGYGARGCNAARGTNAGYGARCAR GAYGGNAARGAYYTNGCNGGNMGNYTNGGNATHCCNTTYTTYGARACNTCNGCNAARGAR GGNACNGGNGTNGTNAAYGCNATGAARGGNYTNGTNMGNACNATHCCNMGNACNGGNAAY GAYTAYAARATHGTNATGYTNGGNAGYGGNGCNGTNGGNAARTCNAGYATHACNATHMGN TTYGTNAAYAAYGTNTTYGTNGAYGAYTAYGAYCCNACNATHGARGAYTCNTAYMGNAAR ATGATHAAYGTNGAYGGNYTNTCNGCNGTNAGYAARGAYACNMGNAARGCNGCNAARAAR GCNAARAARTCNAARAARAARTCNGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTCNNNNNNNNNNNNNNNNNNNNNNYTNNNN NNNNNNNNNNNNATGCCNACNTCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCN CCNNNNCCNGCNCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTNAAR MGNAARGCNGAYGCNAAYGTNGTNYTNATHTCNYTNMGNCARYTNGARGARGARCCNAAY YTNGTNACNGGNGAYGCNATHCAYTGYAARAAYTGYGARGCNATHYTNACNGARACNGCN ATHYTNGARGCNGAYGGNGAYAARAARATHTGGAARTGYGARTTYTGYGGNCAYACNAAY MGNGAYYTNGARATHGCNGAYGAYGARATHCCNAARGGNGARTGYYTNGAYTAYATGYTN TCNCCNGCNACNCARCCNGAYGTNGARGAR---GARGCNGCNGCNTCNGAYGAYTGYAAR AARGARAARGTNACNCCNGGNGTNATHGTNTAYTGYATGGAYATHAGYAGYTCNATGGCN GCNTGYTGYGARATHCCNGARTCNCARAGYTCNTGGMGNCARGARMGNYTNGGNGTNTCN GAYTCNAAYMGNGTNTCNMGNYTNGARTGYATHCARACNGCNGTNGARMGNYTNGCNGAR CARYTNAARGGNGARCARCCNGARAARCARATHATGYTNGTNGTNTTYAGYTCNTCNGTN ATGGTNAARGCNGGNGGNTCNACNGAYAAYYTNGCNACNTAYGCNGAYGTNGCNAAYACN ACNTTYGARCARYTNYTNGARAARGGNGTNAGYYTNTGYAAYMGNTAYCCNYTNAARCCN YTNTCNGAYTCNTAYGAYGAYGTNACNGCNGCNGTNAARGCNYTNMGNACNACNGGNTGY ACNGCNYTNGGNCCNGCNYTNTCNATHTGYYTNGGNTTYGTNAGYGCNATHCCNAGYTCN GARATHGTNYTNTGYACNGAYGGNGARCCNAAYGTNGGNGTNGGNACN------GGNGGN GCNGTNTTYTAYGARCARGTNGGNACNTAYGCNMGNTCNAARAAYATHACNATHAAYATH YTNGCNGTNGARGGNGCNTCNTGYGGNYTNCARTCNGTNAGYGCNGCNGCNGARCAYTCN GGNGGNACNACNAAYAARYTNAAYCCNGCNGARATHGTNMGNCARYTNMGNTCNATHGCN CARAAYGARGTNGTNGCNACNTCNGTNACNGTNNNNTTYTTYYTNCAYCCNGAYTTYGTN TTYGAYGARCCNGARTAYGGNGARAAYYTNAGYCARYTNGARAARGARGTNGGNTCNGCN MGNYTNGARACNGAYYTNACNTTYMGNTTYAARYTNMGNGAYCCNAGYAARAGYAAYATH AARTCNGTNCCNTTYCARGTNCARATHAAYTAYACNAARAARAAYGGNATGMGNTGYYTN MGNGTNYTNAGYAARMGNAAYGARGCNACNATGTCNMGNCARGARATGGARCARAAYATH AGYGCNACNGTNYTNAGYGTNTCNGCNATGAARACNACNGCNCARYTNGCNAARGGNGGN AARGGNGTNGARGCNCARCAYATGYTNAARAAYTTYAARMGNATGGTNAAYMGNGGNGCN AARACNGCNGARCARAARGARGCNAARYTNGCNTTYAAYAAYGARYTNGARCARTGGGAY GAYCAYYTNACNTAYAARAAYAARGCNTTYACNGCNCCN--------------------- TCNCAYATGCARTCNGAYATGGCNACNAAYATGATHCARCAYGTNGGNMGNAGYAARTTY AGYCARGCNATGTCNMGNAARAARATGGGNGCNTCNAGYAARGCNGCNTAYTAYTCNTAY AARAAYGAYYTNGTNTTYGGNACNYTNTAYCCNGCNTAYGCNTCNTAYAARGCNGTNMGN ACNAARAAYGTNAARGARTAYGTNAARTGGATGATGTAYTGGATHGTNTTYGCNYTNTTY TGYAGYATHGARACNTTYTCNGAYGTNTTYYTNTCNTGGYTNCCNTTYTAYTAYGARYTN AARATHGTNTTYGTNGTNTGGATGYTNTCNCCNYTNACNCARGGNTCNAGYTTYATHTTY AARAARTTYGTNCAYCCNCARYTNGCNMGNMGNGARAARGARATHGAYGARATGATHGCN CARGCNAGYAARCARGGNTAYAGYACNYTNYTNACNYTNGGNTCNAARGGNGTNAAYTAY GCNTCNCARATGGTNATGMGNACNGCNATHATGGGNCARTCNAARYTNGTNGAYCAYYTN MGNMGNAGYTAYAGYACNAGYGAYYTNACNGAYGAYGGNCARTCNGTNATGCARMGNCAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GTNGAYATGCCNGTNATHACNACN YTNTAYTAYTGYTCNYTNTAYCAYTTYGAYYTNTCNGARAAYTCNYTNGGNAGYCCNGCN GCNATHMGNAARMGNCAYCAYATHTCNGARAARCARTTYGTNTGGACNAGYATHGGNGCN MGNGCNAARYTNMGNCARTGGAARGAYATHGARACNATHYTNACNACNAARGGNTGGTTY GGNGGNACNAARYTNAARGCNGTNATHGGNTTYGAYAARATHGTNATGATHYTNCARAAR TAYAAYTCNCCNCCNGAYATHYTNGAYAARTAYYTNGCNYTNATGGAYGAYCCNGARGCN MGNYTNGAYYTNGCNAARAARGTNAAYTGYCAYAARGCNGTNATHGAYACNTAYGCNTCN YTNAARGAYMGNCARTCNYTNGARAAYTAYGCNTCNAARYTNGAYMGNTAYTCNAARGAY GGNYTNTAYGCNTAYGAYGTNYTNAAYGGNTCNGTNATHAARTGGMGN---------GCN GCNGGNYTNACNACNATHATHAARGARGCNAARCCNATGACNGCNGTNGGNCCNTCNCCN GTNAAYCCNCARGCNGTNGTNGTNGARAARCARAARGCNATHGTNAARCCNCARATHATH ACNCAYATHATHGARGGNTAYGTNGTNCAYGAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYCAYACNTCNACNMGNTGYCCNGTNAAYCAY ACNAARGARAARGCNATHGTNAARCAYYTNAAYTAYATHGAYCAYGARAARTCNYTNAAR CAYGCNCARAGYCCNYTNGTNGCNYTNCCNGAYTAYACNTAYCARGAYGGNMGNCCNACN GARYTNACNGTNTGYTAYAARMGNMGNCARGARAARAAYTAYAGYYTNGCNAARCARGTN GTNAARYTNGTNGAYGARGTNMGNTTYGCNCARAAYCARYTNGCNTCNCARGARGARGCN GAYATGAARMGNGARGCNGAYMGNMGNAARGCNCARYTNAARCAYAARTTYAAYGARAAY TCNTCNACNTTYYTNTCNTAYGCNGGNYTNYTNGTNAARTCNTTYACNTCNGAYGARCCN GCNYTNACNCARTGGTGGMGNGGNAAYCARTCNGGNATHYTNGAYYTNACNAAYCCNAAR GCNATHGAYTGGTAYYTNAAYAARACNAARAGYYTNCARAARGARTTYAAYGTNACNTCN TTYAARTTYGAYGGNGGNGARACNCAYYTNYTNCCNGARAARTAYMGNYTNGARAAYCCN GTNGTNAGYCCNAAYTTYTTYTCNAARYTNTAYGCNCARATGGCNTTYGARTCNCARMGN MGNCARGARGTNMGNACNGGNTTYMGNAGYCARCAYYTNCCNATHYTNGTNMGNATGATG GAYMGNGAYAGYAAYTGGGGNGGNAAYGCNTAYGAYTCNGGNGAYATHGAYAARACNGTN ATHCCNGAYCCNGARYTNTTYGTNMGNTGGYTNCARGCNACNACNYTNATGCCNAGYATH CARTTYTCNATHCCNCCNTGGTCNTAYAAYGAYACNGTNATHAGYATHTCNMGNAARTTY ACNGCNYTNCAYGCNTCNTTYGCNGAYAARATHATHGCNYTNGCNAARAAYGCNGCNAAR ACNGGNGARCCNATHYTNMGNCCNATHTGGTGGYTNGCNCCNGAYGAYTCNGARGCNYTN AARATHGAYTCNGARTTYATGYTNGGNAAYGAYGTNYTNGTNGCNCCNGTNYTNGAYAGY GGNAARGCNAARMGNGAYATHTAYYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGTCNATHGARYTNGTNTCNAARTGYYTNGAYYTNACN------GTNACNGGNACNGGN AARGGNTCNAARGGNAARAARAAYMGNAARYTNAARACNAAYGAYGCNATGGARATHATH CCNACNAAYMGNCAYGGNGTNTGGAARGARYTNMGNAARGTNMGNAARAARCARYTNAAR GARATHAARAARAARMGNAARGCNGARATHTTYAARTCNGCNATHGARGTNTAYAARGAY AARCAYGAYATHGAYCAYACNGAYAGYAAYGTNGARACNYTNYTNAARATHTCNAARYTN GGNAARGTNGAYTCNAARTGYGCNGARAARATHYTNTAYCAYCARCCNTGYMGNYTNTCN MGNGAYATHAARCCNGGNACNGARGTNTCNGARCCNACNACNGTNTTYACNGARGAYGAY TTYGARGCNTTYGCNAARGAYTAYCARCCNAAR------ATGTCNGCNCCNCAYGGNGGN GGNAAY------------CAR---CAR---------------------GAYMGNCARAAY MGNAARYTNYTNYTNGARCAYATHCARGARCARAARAARMGNYTNCARCAYGGNCAYCAY TCNTCNACNACNAGYCCN---GCNCCNTCNATGAGYTCNACNCCNGCNACNYTNATHAAY AAY---CCNTCNTCNATHCCNGGNYTNTCNGCNGCNGARTAYGCNACNATHAGYAAYCCN CARCARMGNGCNGCNYTNCARCAYGCNCAYGCNAAYTCNGTNGGNTTYTTYATHACNCAR GAYTCNTCNTTYGGNAAYYTNATHYTNCCNGTNYTNCCNMGNGCNCCNGAYACNAARGCN GARACNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CAYGARCARMGNCARTTYATHTAYYTNGCNATGAARGCNYTNGGNGAYCAYCCNGTN GTNAARCARATHGARAARGCNATGGCNGARYTNCARACNAAYMGNCCNGAYYTNAARGAY TAYGTNCCNTCNAAYATHAGYCARGAYTTYACNTGYGARGAYGGNAARATHYTNMGNTTY TCNGTNGAYGGNTCNYTNGARMGNYTNTAYGAYCCNTTYAAYAARGTNGARTGGGCNTCN CCNATHAAYMGNYTNGGNCARYTNAGYTAYAAYACNTTYGTNGARGCNGAYTTYGTNGCN ATGGCNAARCARTAYAAYTAYATGGCNGGNGTNGGNTTYGAYAARCCNAAYGTNACNGCN AAYGCNCAYCCNGARAARAARYTNTGGGAYATGGGNGTNATHAGYTTYCAYMGNAARAAY GAYTTYTCNTGYGAYTTYTGGYTNGARYTNAARACNTTYGAYATHGARACNGAYATHAAR TAYGGNGCNCCNATHAGYTTYTTYYTNAAYTAYGTNTCNGTNCCNAAYMGNGGNYTNAAY GTNTCNGTNYTNYTNYTNAAYAARACNACNACNMGNYTNCCNGARTCNGTNTCNYTNAAY TTYACNCCNMGNGAYYTNGAYACNMGNTGGACNATGACNAARATGGGNTAYGAYYTNGAY CCNTGYTAYGTNGTNYTNAAYGGNAGYCARTAYGTNCAYGCNGTNTCNACNGTNAARATH TCNAGYAAYAGYTAYAARAGYGGNYTNATHATHGCNGGNCAYGAYTCNCCNYTNATHTTY TGGGGNACNACNGAYMGNGCNCCNTCNCCNTTYCCNGTNCCNYTNCARCCNTTYAAYTGY YTNACNYTNAAYTCNGTNGCNTTYAAYYTNTAYAAYAAYATHTGGAAYACNAAYTAYATH TAYTAYTAYCCNTAYAGYGAYTAYGAYTCNAGYTTYAARTCNMGNTTYAGYATHTAYTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNGGNTTYGGNAGYTCNGCNCCNMGNGGN GGNCCNAAYTCNTCNACN------------------------------------------ TCNCCNTGYGCNTCNATHTCNTCNTCNTTYCAYAAYAGYGCNACNGTNCCNCARTCNAGY CCNGTNMGNATGMGNGAYMGNTCNTCNCCNMGNAARCCNMGNCCNGCNAGYGTNGGNACN TCNATGCCNAGYTTYGTNGGNGCNGARCCNGCNAARGCNTCNMGNAGYAARAGYTCNGAY MGNATGGCNMGNGAYMGNTCNAARGCNMGNCCNGGNMGNMGNAARGAYAARGTNGCNAAR GAYGCNAARGGNAARGAYAARAARGARGARGCNGARGAYGARAARGAYGGN--------- ---------GGNACNACNACNACNACNAARAARGGNMGNGTNTCNYTNTCNTTYTTYGAY MGNYTNGCNACNCCNAARTTYCAYMGN---AAYCARGAYGARCARAARGAYACNTCNTCN GCNAARAARGARTCNCCNATNGTNMGNYTNTCNCCNMGNAARGCNTAYTCNACNACNAAY YTNTCNACNATHAARAARAARACNTCNTTYMGNGARAAR--------------------- TCNAARGGNGAYTCNAGYTCNACNAGYAGYACNCCNMGNCAYACNCCNMGNMGNGAYCAY TCNGCNTCNTCNMGNGTNTCNGGNGTNTCNCCNGCNCCNGGNGGNATHATGTCNAARTCN ATGTCNTCNGCNATHTCN---CCNMGNGTNACNCCNCCNCCNACNTCNTCNTCNCCNCAY CCNCCNACNCCNAGYATHAGYGTNAGYTCNCAYCARGGNGGNGGNAGYAGYGCNACNCAR GCNCCNAGYTCNGARGAYGGNACNTCNACNTCNMGNACNGGNGGNGGNGGNCARGAYATH TCNAARGARGARTAYAARGCNAARATHGCNGARAARMGNMGNCARGCNMGNGARAARGCN GARAARGARGCNGARGARGARMGNAARMGNCARGARGARGARMGNYTNGCNGARGARGAR MGNATGMGNCARGARGAYGARGARCARCARMGNYTNGARGARGARAGYATHMGNYTNGCN GCNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGGAYAAYCARTTYTCNCAYYTNCCNGCNCCNCCNCCNTAYTCNGARTAY CCNATHATHAAYGARGTNGAYMGNGAYACNYTNAARATHATHAARACNGCNGAYATHACN AARTAYYTNAGYGTNCAYTCNGGNACNGCNCAYCCNCAYATHGARMGNGAYGGNACNGTN TAYTAYTAYGGNACNYTNTAYGAYTAYAARAARGCNTAYAAYATHATHAARGTNCCNMGN CCNAARCARGAYGARGGNYTNATGACNAAYTGYCARATHGTNGGNACNATHCCNAGYMGN TGGAARGTNAAYATHGCNTAYAAYCAYTCNTTYGGNATGTCNGARAAYTAYTTYATHTTY YTNGARYTNCCNTTYGTNGTNGAYACNATGMGNACNYTNACNAARGGNYTNMGNGCNGCN YTNGCNGAYGCNATGAARTCNTAYCCNGAYGARGAYATHYTNATHCAYGTNATGGARAAR AARACNGGNAARMGNYTNCCNATHACNTAYCARGCNCCNCAYGGNTTYGCNTTYCAYTTY ATHAAYTGYTAYGARGARGARGAYCAYYTNATHGTNGAYGTNTGYYTNTCNGAYAARTCN GTNAARGAYYTNTAYYTNGARACNYTNGTN------GCNAAYGARYTNACNGCNACNAGY GGNTTYGCNMGNTAYGTNYTNCCNYTNAAYGTNGAYGGNGCNAARGTNGGNGAYAAYGTN AAYMGNYTNTCNGGNAGYGARGCNGTNGCNGTNYTN---TCNAARGARAAYYTNGTNAAR GTNAARGCNGAYAARCCNTTYGGNGAYGAYYTNTTYTTYGARYTNCCNCARATHAAYTAY AGYGTNAAYGGNYTNAARTAYMGNTAYATGTAYGGNTCNACNTTYTTYAARAAYTGYGAY AARAARGTNYTNAARYTNGAYYTNGTNAAYAAYACNGCNAARACNTGGATGTGYGGNGAR AAYCAYGARCCNTCNGARCCNGTNTTYGTNCCNMGNCCNGAYGCNACNGAYGARGAYGAY GGNGTNATHYTNTGYCCNATHGTNTCNAARACNTCNGAYMGNGARTCNTTYYTNYTNATH YTNGAYGCNGCNACNTTYCARGARATHGCNMGNGCNTCNYTNCCNACNGAYGTNMGNATG AGYTAYACNYTNCAYGGNATGTTY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNCCNCCNATHGGNCCNMGNCCNGARTAYGTNAARTCNMGN AAYGGNATHYTNAARATHGCNGARGTNATHYTNTGYATHYTNGTNYTNATHTGYTCNTCN GTNGTNTAYTGGTCNCAYYTNGGNGGNGGNTGGGTNCARTTYGTNGCNGCNTCNGGNTTY ATHTCNACNGCNATHYTNTTYYTNYTNCAYTTYYTNACNATHGTNCCNMGNATHCCNGGN CCNTGGACNTTYATHGARTTYATGTTYTAYTGYATHTAYTGYYTNYTNTTYATHATHGCN GCNATHGTNTGYTCNGTNMGNGCNCAYYTNCAYGAYGCNATHGGNGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ACNATHAAYYTNMGNGTNAARCCNAARGARCCN GGNACNYTNAARGTNCARGGNTAYTCNACNGTNGTNTGYGGNGTNAARAGYAAYTGYMGN YTNMGNGAYYTNATGGGNYTNAARCCNTCNCCNYTNACNGAYATHACNATHCARGTNATH CCNMGNYTNCCNTAYGTNAAYATGTCNTGYTCNYTNCCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TGYCCNGTNTGYAARTGYGTNCAYGGNCARAARGTNGGNAAYTGYCCNGCNGGNACN ATGGTNTGGMGNGCNATHAARGAYYTNACNYTNGGNTAYGARMGNTCNMGNGGNACNATH GARGTNACNTAYAAYATHAGYMGNGGNAARCARGCNCCNGGNCAYCCNAAYCCNGGNMGN CCNTTYAAYGCNMGNGGNTTYCCNMGNCCNGGNTAYYTNGARAAY--------------- ---------------GTNACNGCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARYTN CARGCNCARGGNGTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR YTNTTYGGNAAYMGNTCNCAYAGYCCNGCNATGGAYGARTTYYTNGAYATGATHGGNCAR MGNGTNCARYTNMGNGAYTTYAARGGNTTYMGNGGNGGNYTNGAYACNGTNCAYAGYCAR ACNGGNGARGARAGYGTNTAYACNAARTAYAAYGGNAARGARGTNATGTTYCAYGTNTCN ACNYTNYTNCCNTAYACNGARGGNGAYCCNCARCARYTNGTNTTYCARGARGARAAYACN CCNTTYGTNCCNGAYATGATHGCNTCNCAYTTYYTNCAYTGYTTYATHGTNGTNTGYCCN YTNCAYAARCARGGNGARACNCCNMGNTAYCARATHTCNGTNGCNGCNMGNAARGAYGTN CCNMGNTTYTAYCCNCARYTNCCNCARCCNGCNGARTTYTCNAARGGNGAYGARTTYMGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGAYCAYCAYTAYGGNGTNGCNGTN ACNAAYAARTTYGCNYTNTTYACNGAYGAYGAYGARGAYCCNATHGARATHAAYGCNCAR AARGAYGARGAYAARAARGCNAARGCNAARGARGARGCNGAYAARAARACNGAYAARCCN GCNGCNCCNCARACNGAYGAYGTNGARCARAAR--------------------------- GARGTNGGN---------GAYAARCARNNNGGNAARMGNAARAARAGYMGNGGN---AGY ---GCNMGNAAYMGNGARCCNMGNGARYTNMGNGARAAYGAYGGNGAYMGNMGNTCNMGN ---MGNCARGGNCCNMGNGAYTTYAARGAYGGNAARCCNCCNMGNGAYTAYAARGAYGGN AARGCNCCNMGNGAYTAYAARGAYGGNAARGCNGGNGAYGARAAYGTNCCNCCNGARTTY MGNGARCARCCNCARGGN---GGNTTYAARMGNMGNGARGAYMGN------GARGGNAGY GGNTTYGGNGGNGARMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNAGYMGNGGN GGNGARMGNGGNGGNGGNTTY------GGNCCNMGN------------------GGNGAY CARAARMGNGARTTYGAYMGNCAYAGYGGNACNGAYMGNACNGGNATHAARTCNATHGAR AARAARGARGGNCAYGGNGCNCAYAAYTGGGGNAGYTTYMGNGAYGAYATHGARGARCAR GGNCARGTNAAY---------GCNTCNGARGAR---ACNACNGARAARGARAGYCARCCN GARAARACNGARYTNAAYGARAGYGTNGARGGNGTNGCNGTNACNGARGARGARGCNCAR CCNCARCARATGACNYTNGAYGARTGGAARGCNYTN------CARGTNAAYAARCCNAAR CCNAARTTYAARATHMGNCARGCNGGNGARGGNGTNGAYTCNGGNCARTGGAARCARGGN GTNGARTAYCARAARAARCCNGAYGARAGYCARGCNCAYGGNGARCAYGARGARGGNGAY CAYAAYGAYCCNAAYCAYGAYAAY------------AARCARYTNYTNTCNGAYATHMGN ATHACNTTYAAYGAYAAYCCNMGNMGNGGNMGNGGNMGNMGNGGNGCNMGNGGNGGNGGN ATGGARMGNGGNGCNGGNGGNMGNGGNGGNCCNMGNGGNAGYGGNGGNMGN------GGN GCNCCNMGNGGNTTYGTNAAYAAR---AARGARGCNGCNCCNMGNTTY---GAYGARACN GAYTTYCCNTCNYTNYTNAARACNGCNGCN------------GGNGGNMGNAARAARTTY YTNTAYTCNGGNCCNGTNAAYAAYAAR------MGNCCNGARGARTGGTCNTTYGTNCCN AARGCNACNAGYCAYGARCCNAGYCCNMGNGCNGGNGTNCCNGTNGAYYTNGAYAAYGTN TGGAGYATHMGNAAYGTNTCNATHGGNGGNACNGCNACNTCNGTNMGNTCNGARCCNGTN TCNTTYAARCCNGARGGNYTNACNAARACNTCNCAYTCNTCNTTYTAYTCNMGNCAYGGN GGNATGAAY---GGNMGNACNGGNAGYCCNAAR------GTNAAYAAYCARGARAAYGAY CARAARTCNTCNTCNYTNTGGTCNAGYTCNGGNCAYAARYTNGGNCCNACNTCNCARMGN YTNCAYCCNCCNACNTTYCARAAYCCNACNGARAAYGCNTTYMGNAAYCCNMGNTCNAAR MGNCARAAYCCNTCNCCNTTYGAYTAYGAYATGAAYGAYTTYATGGARGCNAARCARTTY TTYGTNATHGGNYTNAGYGGNGTNACNAAYAGYGGNAARTCNACNATHGGNTCNMGNYTN TCNAARACNYTNCCNAAYTGYACNTGGATHTGYCARGAYCAYTAYTAYYTNGCNGCNGAY GAYCCNMGNGTNGARATHGARTCNAAYGGNATGCARAAYTGGGARAARYTNAGYTCNYTN GAYATGGAYACNATGYTNAGYGAYGTNTTYGGNTGGATHGARMGNCAYAARTCNYTNGCN CCNCCNTCNAARGCNTTYYTNGTNATHGARGGNTTYACNATHTTYAAYCAYMGNCCNYTN TCNAAYYTNTGYGAYAARAARTAYTTYYTNCARGTNGAYAARGAYACNGCNTAYGAYMGN MGNTGYACNMGNGTNTAYGAYCCNCCNGAYATHCCNGGNTAYTAYTCNGARATHGTNTGG CCNATGTAYYTNAARAAYYTNACNGAYYTNGARGAYCARAARGAYATHGARTAYGTNGAY GGNYTNTTYGAYYTNGAYACNYTNTAYCARCARATHYTNMGNGARGCNGCNAARYTNTAY GGNGTNCCNCAYAAYACNYTNMGNGAYMGNATHMGNGGNAARACNCCNATGMGNATGGTN MGNMGNACNGTNYTNTCNCCNGCNAAYGARGGNAARYTNGTNTCNTGGYTNGARGAYTCN GCNMGNYTNCAYGTNMGNCAYMGNAAYAARAARCARCAYGTNMGNGAYGTNAARGTNACN GCNGAYAARGARAARGTNTTYATHTCNAARAARAGYAARAARAARYTNCARTCN---GCN ATHYTNGARGTNGARGAYAARAGYATGATHATHGCNGAYAARCCNGTNGAYAAYGTNTGG GTNMGNAARTTYTAYCCNACNCCNAARTTYTCNATHGAYACNGCNATGGARMGNCAYAAR AAYTTYGCNCARCCNGCNATGYTNGAYAAYATGGAYGGNYTNGTNTAYATHGAYATGYTN YTNGAYTTYTCNACNAARAARAARACNAARTTYATGAARAAYATHCARTCNACNATGYTN YTNCCNCAYCCNTTYTCNTGGGGNTCNCCNCCNTCNATHYTNGTNTTYTGYAARGARGAR GARCAYGCNAAYATGGCNYTNTCNATGGGNGCNAARCAYGCNGGNACNCCNGARGAYGTN ATHAARATGATHGARAAYGGNGTNYTNGAYCCNAARGAYTTYCAYCAYGTNYTNGCNACN GCNGAYTGYACNGTNGARATHACNCCNGCNMGNTCNTAYTTYAARGARAARTTYCCNCAR MGNGCNAARGGNAAYYTNGGNACNGAYYTNAAYGCNATGTGGAAYYTNTTYTAYACNGGN TAYACNTAYCARTCNATGAGYYTNTCNGARTCNCARGGNAARYTNCARGTNCCNGTNGGN CARYTNAAYCARCCNACNAGYGARYTNGTNGCNAAYGTNGARGCNTTYATHGARTCNGTN TGYAARCAYMGNAGYGTNGCNYTNGGNCCNTTYATHCARCARATHTCNGTNGTNGCNCCN CCNTCNCCNGARGARTTYYTNATHAARGTNGARGAYTGYGTNCCNGGNTAYAARAAYGAR GARGTNGAYTCNGAYGAYGARGAYGTNGCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TTYGARATGTGGCAYGGNYTNGTN YTNATHTTYGCNYTNATHATHYTNYTNGTNATHGTNGTNGTNTTYGTNAARAARMGNAAR AAYAARAARYTNATHTTYGTNGAYGAYACNYTNCCNCCNCCNTCNACNACNATHATHGTN AAYGGNGGNCAYYTNGCNTTYGARAAYAGYATGTAYGTNGARACNAAYMGNAAYAAYACN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNTCNCCNGAYATGGGNMGNYTNAARTGYTCNTGYCAYTTYAAY TTYATGTTYGAYGTNTCNTGGYTNGTNCARCARTAYTCNCAYAGYGAYMGNACNYTNCCN ATGYTNYTNGTNCAYGGNGAYCARGGNMGNGCNGARAAYGAYYTNAARAAYAARGCNTCN CCNTAYCCNAAYATHTCNYTNTGYMGNGCNMGNYTNGAYATHCCNTAYGGNACNCAYCAY ACNAARATGATGTTYYTNYTNTAYCAYACNGGNYTNMGNATHGTNATHCAYACNGCNAAY YTNATHTCNAAYGAYTGGCAYCARAARACNCARGGNYTNTGGATHAGYCCNACNTTYCCN MGNYTNAARAGYCCN---TCNGAYCCNGGNGARTCNMGNACNAARTTYAARGCNAAYYTN YTNCARTAYGTNTCNGCNTAYAARTCNGCNAARYTNACNACNTGGAARAARATHATHTCN GARCAYGAYATGTCNTCNGCNAAYGTNCAYATHATHGCNTCNGTNCCNGGNMGNCAYACN ATGAAYGAYAARCAYATGTGGGGNCAYYTNAARYTNAARAARATHYTNTCNGCNGTNGGN CCNGAYCARGGNYTNGTNAARAAYTGGCCNGTNACNGGNCARTTYTCNAGYATHGGNTCN YTNGGNGCNAAYCARGAYGCNTGGYTNYTNAGYGARTGGGGNCARTCNATGTCNACNTGY MGNAARTCNYTNCCNTCNTCNATHCCNGCNTCNAARYTNCAYYTNATGTTYCCNTCNAAR GAYAAYATHMGNYTNAGYYTNGARGGNTAYAAYGGNGGNGGNTGYGTNCCNTAYTCNATH AARACNGCNTGYAARCARCCNTGGYTNACNCCNTTYTTYTGYCARTGGMGNTCNGARGGN MGNGGNMGNTCNAARGCNGTNCCNCAYATHAARACNTAYACNMGNTCNTCNCCNGAYGGN ACNGARGCNGCNTGGTTYATGGTNACNAGYGCNAAYYTNTCNAARGCNGCNTGGGGNGCN TCNGARAARAARGGNAGYCARYTNATGATHMGNTCNTAYGARATGGGNGTNYTNTTYYTN CCNGARGAYTTYGGNTAYAARAAYTCNTTYAARGTNAGYAGYCARYTNGAYAARYTNACN GAYCCNGARGTNAARATHTTYCCNYTNCCNTTYGAYYTNCCNACNACNACNTAYATHAAR GGN---AARAARTCNGTNGARYTNTTYTAYGAYGTNGTNTCNCCNTAYTCNTGGTTYGCN TTYGARGTNATHYTNMGNTAYCARAAYMGNTGGAAYATHAAYYTNAARYTNMGNCCNTTY TTYYTNGGNGGNGTNATGCARCARGCNGGNAAYMGNCCNCCNGCNATGGTNCCNAAYAAR GGNATGCAYYTNACNACNGAYGTNGARMGNTGYGCNMGNTAYTAYGARGTNCCNYTNATH ATHCCNAARAAYCCNGGNGARYTNATGTTYGARAARGGNTCNYTNAARGCNCARMGNTTY YTNACNGTNYTNGAYATGAARAGYCCNGARAARGTNGARGCNGTNTCNMGNGARTTYTGG ATGMGNGGNTGGTCNMGNGAYGARGAYYTNTCNGAYGAYACNAGYYTNGCNGARGCNGCN AAYAARGCNGGNYTNAGYCARCARGAYATHMGNGAYTGYYTNTCNMGNYTNAARGAYCAR GAYGTNAARGAYMGNYTNAARAAYGCNACNGAYGARGCNATGGARYTNGGNGCNTTYGGN TCNCCNATGATHGTNACNGARGTNGAYGGNAARAARGARTGGGTNTTYGGNAGYGAYMGN TTYCCNATHYTNGCNCARATHYTNGGN--------------------------------- ------------------------------------------------------------ ------------------------------YTNAARGCNGCNMGNAGYYTNGCNATHYTN GGNGCNGTNATHYTNGTNAARTGYTCNGTNGGNAGYGTNYTNACNYTNATHGTNGCNAGY MGNGGNGAYMGNCARAARTAYYTNCCNTAYATHATHTGYGGNTTYTGYTTYGCNGGNGGN TTYTTYTCNTTYGTNGGNGAYATGGTNGTNGCNGCNAAYTAYAARGCNATH---AARTTY GCNCAYATHGGNGARMGNTCNGARGCNTTYMGNGAYGARTTYGGNGAYGCNTTYTCNYTN GGNTGGAGYTTYAGYYTNGAYYTNYTNGTNCCNATHYTNGCNGTNATHTGYGGNGTNTGY CAYYTNYTNGGNCAYMGNTAYAAYYTNYTNGCNGARGARTAYTCNACNGCNACNAAYGTN GCNMGNGTNYTNGCNATHACNTCNGTNGCNYTNGTNTTYYTNTAYMGNGGNTCNATHCAR GGNCAYATHGAYAAYYTNTGGACNTAYYTNMGNCARGAYACNYTNTTYCARTCNGCNCAY TAYGARACNATHTAYGTNACNATHGTNTAYACNATHYTNATGATHTTYTAYCCNTTYGCN ATGCAYCAYATHCCNTAYTTYMGNCARTTYAARGTNTCNGARGAYGTNAARTAYGTNAAY CARACNGTNYTNGGNATGGGNGTNGAYYTNGTNTTYCAYYTNAGYCCNYTNYTNGTNGCN GAYATGYTNATHATHAARMGNTAYCCNGGNGTNCCNTAYTCNGARATHCAYACNMGNAAR CARGAYTGGGTNGTNMGNACNMGNCCNYTNCCNMGNGAYCCNCCNGARGTNATH------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GCNTGYATHGAY YTNACNGTNAAYATHGGNGGNGAYGARGTNATHGAYYTNACNCAYAAYAAYAGYATHATG GAYTCNCCNGTNGTNGTNATHAGYGCNGCNGAYGAYGTNGGNCCNATHMGNMGNCARMGN GGNAGYGGNMGNCARGGNMGNMGNMGNTCNAAYGTNMGNGCNAGYCCNCCNCARGGNGCN GTNTCNTCNTCNTCNATHCAYTCNCCNACNCCNTCNTCNTCNMGNGCNGGNMGNATHCCN ATHGAY---GAYAGYGAY---GAYGARYTNCCNGAYATHCCNTTYGARATHCCNGCNGAR AGYTCNAARGCNAAYGCNAGYTTYTGYAARTCNCCNCCNYTNCARATHCARTGYCCNGTN TGYYTNGAYGAYYTNAARCARATHAARTCNAGYAARAARMGNGTNATGTCNACNATHTGY GGNCAYATHTTYTGYGARGARTGYATHGTNAAYGCNATHAARACNTAYMGNTCNTGYCCN ACNTGYMGNAARCAYYTNGCNCARAAYAARATHCAYCCNYTNTTYYTN------------ TCNYTNAARGTNTCNGAYCCNGAYTCNGAYGTNACNYTNTCNCCNMGNGARGAYTAYAAR YTNAARMGNCARAAYMGNAGYAARACNYTNCCNGGNAGYGCNGARGAR------GAYAGY TCNAGYAARATHCARMGNGCNAGYTCNCAYMGN---GCNCCNGTNTCNAAYTCNCCNTCN GARGAYAARCCN------AGYATHGCNCCNGCNTCNTCNAGYGTNAARAARYTNGGNGCN ACNMGNTTYAGYCARTTYGCNTCNAGYGCNTCNTCNGARCCNTCNTGGGTNAAYAARGCN AARCARAARAARTCNGARGAYGTNGARGARCARGARCARAARAARCCNTCNTCNGARGAY AAYGTNMGNMGNCARAGYCAYGARAAYGTNYTNGCNTCNGCNTCNAARTCNCARGARCCN GCNTCNCARTCNAARAAYGTNCCNTCNTCNTCNGGNTCNAARGAYACNAARAARGGNAGY ACNGAYATHAAYTCNAGYAARGTNACNGARTCNGARAAR---------------GAYAAR CCNAAYAGYAARMGNCCNAGYATHGAYATHTCNAGYATGAARMGNACNAGYATHGAYATH GAYGTNAARGARYTNAGYATHAARCARMGNACNGCNTCNTTYAAYAAYACNGGNAARGTN GARGCNTCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNTGYACNATHAARATHYTNTCNATHGAYATHACNAAYGAYCARTAYGCNTGY TCNYTNGTNYTNGAYGARGCNATGGGNATHGGNMGNGCNATHGCNMGNTGGATHACNCAR AARTTYGTNAGYGAYATGACNAARGAR---------------GARGAYACNACNAAYMGN CCNGTNTGYAARATHAARGGNMGNATGAAYGAYGTNCARAARATGAARGAYAARTTYAAY GAYYTNMGNATHAARGAYCARMGNAAYATHYTNTTYTCNCCNGAYAARMGNGGNACNATG GAYTTYATHAARCAYGCNTCNGAYTGYAGYAAYCARTTYCCNCCNTCNTGGAARYTNGAY GAYTTYAAYAARGGNCARCARAARACNGARTTYCAYATGGTNGAYAGYAGYGTNTAYCAR AARATHGARGGNYTNGTNYTNAAYACNTGGGARACNGGNATGGTNGGNMGNGGNGCNGAY GCNMGNAAYATHGTNCCNAAY---TCNGTNAARGTNGTNAAYGTNGARMGNATHGARAAY CCNATHYTNTTYYTNAARTAYTTYGCNAARMGNTCNACNATHYTNAAYGARATGAARACN MGNGAYYTNYTNTGYGCNGAYYTNGGNCARYTNCCNGGN---AGYAARGGNCARTCNAAR GCNATGACNCAYYTNGAYGAYGCNATGAARCARGARYTNGTN---CAYGARATHAAYGAR CARTAYYTNTTYCAYGGNACNAARCARGARATHGTNAAYAGYATHGTNGARCARGGNYTN GAYAAYMGNYTNTCNAGYTCNGGNGGNATGYTNGGNCARGGNGTNTAYACNGCNGARAGY TCNACNAARGCNGAYCARTAYACNGAYGAYMGNGGNAAYMGNYTNCCNAAYGGNTCNAAY YTNACNATGTTYYTNATHMGNGTNGTNYTNGGNGARGTNTTYATHYTNGGNGAYAAYCAY GARAGYGTNCARGCNAARGAYTCNGTNAARYTNAARMGNCCNCCNTGYATGAGYTGYYTN AARGAYATGTGYMGNGGNMGNMGNGARTTYGTNGTNTAYAAYATHCARTGYTAYCCNGAR TAYMGNATHACNTAYCARMGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GARAAYCARTTYGARCAYAARYTNGGNGAR TTYATGYTNACNATHAARCARATHYTNCCNCARAAYACNCARGTNATHAARACNATHAAR GARTTYCAYACNAAYYTNAARATGGCNMGNGGNGTNAARAARGGNAAYTAYGAYAAYATH GAYCAYTAYYTNMGNTCNYTNGARTTYTTYMGNAARTGYTTYCARGARATHGARMGNGAR ATHGTNCAYCCNATHTGYCARATHCARGCNATHTGYGARAAYGARAARCARMGNACNYTN AARAARACNATHAARAARTGYGCNTCNGARATGYTNGGNTAYYTNAARCCNGAYGTNGAY YTNCARAARGTNMGNCAYAARGARTGGGARGGNAARGTNYTNGCNMGNGARCARGCNYTN TTYTAYGGNYTNATHAGYYTNATHCCNATGAGYGTNGAYMGNYTNACNACNATHGAYTAY AGYGCNGAYGARTAYATHAAYGAYTTYCCNGAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GCNAARYTNMGNAAR ATHGCNATHGCNAAYGCNYTNAAYTCNATGAARTCNGGNCARCCNGTNCCNGTNCARYTN GAYGTNGCNACNGTNAARTCNGGNGGNAARTCNGTNGARGARYTNACNGAYTTYTGYAAR MGNATHTCNGARAARGARCARGARAARGTNGAYAAYGCNATHAGYGAYAGYAGYGARGAR GARGCNCCNCAYAGYGAYGARGARGARCCNYTNATHCAYCAYCCNTTYAARGTNAARGAY ACNTCNGCNAAYATHGTNATGAAYATHMGNAAYGCNAARCARYTNCCNGTNYTNACNCCN TCNGARAARCARGCNCARCARGCNTCNYTNMGNYTNGCNTTYCCNGTNTCNAGYGGNACN CAYCAYMGNGCNAGYGARTCNGARTGGGTNCCNGTNGAR------------------AAR ACNACNGCNYTNGCNGTNCCNACNACNAGYAARCCNGTNAAYTCNAARAGYACNACNGAR CARCCNGARAARAARGAYAGYATHTTYCCNACNACNACNTCNAAYGTNGAYATHGGNGCN ATHATHTCNGARMGNYTNCARGCNGTNMGNAARYTNCARGCNAAYCCNTAYGAYGTNCAR GCNYTNAGYACNATGCAYAARGCNCARGARAARGCNAGYCARTGGGCNCARTCNAARCAY YTNCCNGGNCARTTYGTNGGNAGYACNGGNGCNCARGTNATGTCNCARGARGARYTNATG GGNGAYAARMGNMGNCARGCNTGGGTNAARAARACNCARTTYAGYACNGCNACNCCNGTN AGYGGNGGNATHGGNATGTTYYTNYTNCARAARATGGGNTGGAARCARGGNGARGGNYTN GGNAARAAYAAYGARGGNAGYACNCARCCNYTNCARYTNGAYATHAARATHGAYMGNAAR GGNYTNCARAGYGCNGCNGAYAAYCCNAARTCNAARCCNCARATHGCNCAYGTNCCNCAR GCNAARGAYYTNTCNCAY------------------AARCAYCCNGTNTCNGCNYTNATG GARYTNTGYAAYAARMGNMGNTGGGGNCCNCCNAAYTTYACNGTNGTNCARGARGAYGGN CCNGCNCAYAARAARTGYTTYYTNTTYAARGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNGTNGTNCARGCNGARGARYTNGGNTGY GARGGNAARGTNGARGARTCNCARGGNGTNATGAARYTNGTNGAYCARYTNAARGARGAR MGNCAYCARYTNGARATGMGNCCN---ATGATGCARGAYGAYGGNGGNCCNYTNATGAAR CARATGGARGTNTGYGAYGTNTGYGGNGCNTTYYTNATHGTNGGNGAYGCNCCNCARMGN CARGAYGARCAYYTNATGGGNAARCARCAYGCNGGNTAYGCNCARGTNMGNGCNGARATH GAYMGNMGNAARCARMGNGTNMGNGAYGARACNGARGCNMGNGARGCNAAYGARAAYMGN YTNMGNYTNGARMGNGARGARMGNGARAARGARMGNCARMGNGARMGNGAYGARAARMGN CARAARGARAARGAYGTNGARMGNMGNMGNGAYMGNGAYMGNMGNMGNMGNAGYMGNTCN MGNAGYMGNGAYMGN------GGNAARGAYMGNMGNMGNTCNMGNAGYMGNGAYMGNMGN MGNCARMGNAGYTCNAGYMGNGAYMGNMGNACNMGNMGNAGYMGNAGYMGNAAYMGNGAY ------------------GGNTCNGGNMGNAGYAARMGNTCNMGNMGNTCNTCNAGYMGN GAYMGNAARMGNGAYCAYMGNMGNTCNMGNGAYMGNAARTCN------------MGNAGY MGNTCNMGNGAYMGNAARGAYATGAGY---------MGNGAYAARGAYYTNAAYGGNGGN AGYYTNAGYAGYMGNGAYGARAAYAGYMGN------------------------------ ---------YTNGTNATHTCNTGYCCNAARGARTTYATHGCNYTNATHTCNTCNCAYYTN AAYGGNAARGAYGGNCARAAYTGGGARCAYYTNYTNAGYYTNTAYGGNTGGAAYTAYAAR TCNATHYTNYTNTTYCARAAYAARGARCAYCCNMGNGGNTAYTTYTGYAGYATHYTNAAY GARTCNGARTTYCARGAYTAYACNATHGGNTTYYTNAARGARGAYYTNTAYAAYYTNCCN AARAARGAYACNYTNAGYGAYATHATHGARTGGATHGARAAYTAYAAYATGGAYTTYGAY TCNTCNTCNAARTTYATHGCNTCNYTNGCNMGNTTYYTNCARTCNYTNTGYAAYGGNTAY GTNGARTTYGAYAARGGNGTNGARGTNATHGGNCAYATHTAYYTNAGYGTNGAYAGYGAY ACNGGNMGNAARATHGAYTAYGTNYTNAAYGARAARGTNTGYAARAAYGAYAAYTCNGTN ACNTTYATHAGYAAYAGYTTYCAYGCNCARCCNGCNGARAARCCNCARCCNGTNCCNAAR AARCCNGARACNGAYAAYMGNAAYGARGAYACNGCN------GAYGAYTCNGGNCARTCN GTNCCNAAYAGYACNAAYGTNGGNACNATHGGNGCNCARMGN------------------ ---------GAYGGNYTNAAYAARMGNCCNMGNTCNCCNACNCARMGNMGNATGGGNATG GGNMGNGGNTCNGGNGGNCCNTCNGCNAARTCNCCNMGNTAYCARGAYCARTCNAGYGCN TCNTCNAARTCNATGCAYGAYACNACNTCNGCNAAYAAYAAYYTNAAYAGYGGNGARGAY TAYGARGGNGCNTAY------------GGNGGNGAYGARGAYAAYTAYAGYCARGAYTAY TCNAAYTCNGAR------------------YTNGAYCARAARCCNGTNYTNGARCCNGAY ATHAGYATHGTNAARGARGARTAYATGGCNAGYCARCARCARCCNGGNGCNTCNTAYCAR AAYAAYCARCCNTCNGGNCCNGGNMGNGGNMGNCCNCCNCCNTCNCARCCNTCNTAYCCN ------ATGCAYCARAAYTCNTCNGCNTTYTCNTCNCCNGGNGAY--------------- ------TAYTCNGGNTCNTCNATHGARCCNMGNGAYCCNTCNGARYTNACNMGNGCNCAR CARGARGARYTNGARATGTAYTAYMGNAARGGNACNGAYCARCAYYTNACNTTYYTNMGN AAYATGMGNGARGCNCAYGCNATGTAYCCNTTYACNGGNAARMGNGAYAARGARYTNTTY GAYAARGCNYTNGCNGARYTNYTNAAYMGNYTNCCNYTNATG------------------ ------------------------------------------------------------ MGNYTNTTYGCNTGYTAYAAYGAYGGNATHATHAAYYTNYTNGARAARTAYTTYGAYATG AAYAARAARCARTGYAARGAYGCNYTNGAYYTNTAYAARMGNTTYYTNGTNMGNATGGAY AARGTNTCNGARTTYYTNAARGTNGCNGARAAYATGGGNATHGAYAARGGNGAYATHCCN GAYYTNGCNAARGCNCCNGCNAGYYTNYTNGAYGCNYTNGARCARCAYYTNGCNTCNYTN GARGGNAARAARTCNACNACNCCNACNGGNTCNAGYAARCCNTCNGGNTTYACNACNGCN YTNAAYAAYATGTCNAGYAAYACNTTYACNGTNAGYGARGCNGARAARAARMGNATHYTN GARGARGARAAYCARCARYTNCARMGNCAYAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARGGNCARGCNTTYATHAAYAAYTTYAAYYTNGGNMGNTAYTGGCCNAGYMGNGGNCCN CARATHMGNYTNTAYGTNCCNAARCCNGTNTTYYTNTCNMGNCCNACNGTNAAYMGNYTN TTYYTNTTYGARYTNGARAGYGCNCCNTGYCARACNTCNTCNGAYTGYAGYGTNTCNYTN GTNGAYACNCCNTAYYTNGAYGGNCCNAAYGCNCCNGAYATGGCNGCNGTNGARYTNGAY CCNYTNTTYGCNAARGCNYTNAARYTNYTNCARTCNAARGCNAARGAYAGYAGYTCNCAR YTNAARYTNATGYTNGAYGAYGCNATHGCNGGNMGNAARGGNYTNAARYTNCCNAGYCAR TCNGGNGAYCAYGARAARTCNAGYYTNTCNAARACNAARAGYGAYACNGAYYTNAARMGN AARGARGGNGARAARMGNCCNCAYGAYAARTCNACNAARGAYCCNTTYGARCCNGAYGTN AARMGNTCNAARTTYGAR------------CARATHAARCARCARAARGARAARGARGCN AARGARAARGARMGNGARAARGTNAARAARGARAARGARMGNAARGARAARGAR------ GARGCNCARMGNCARAARGAYAARGCNGARAARGARMGNAARGARAARGARYTNGCNGCN GTNAARCARGAYCCNGAR------ATHYTNAGYGAYGARGARGARACNGCNCARCARATG GAYGCNGGNGAYTTYGCNATHGAYYTNGGNATHGCNTGYGTNGTNTGYMGNCARTTYGAY GTNAGYTCNGGNAAYCARYTNGTNGARTGYCARGARTGYCAYAGYYTNTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TGGACNGCNAAYCAYAAYGARACNGGNAARTGYAGY GTNYTNYTNACNGCNCCNTCNMGNATHAARTCNATHCARAAYGTNYTNMGNCARTTYGAY TAYGARGTNGCNACNTAYGARGGNCCNACNAARGAYGAYGTNAAYTCNAARYTNTCNTTY ACNTGYAAYACNGGNCARATHTCNATHTCNTTYCARMGN--------------------- ------------------------------GTNAAYAARGAYYTNATHCARATHAARACN ACNGAYGARMGNGARGTNCARMGNMGNATHGAYTCNTTYATHATHAAYAARMGNAAYGAR GTNAAYGARMGNAAYATHMGNGARTTYATHTCNCCNTTYTGYTCNGAYCCNGGNAAYAGY TGYGCNMGNGTNGARGCNGTNTAYATHCAYMGNGARGGNATGAARAGYCAYATHAAYYTN AARCAYGTNGAYAAYGCNTAYGGNCCNCARACNMGNMGNMGNCCNGARGAYATGGAYGGN MGNCARCCNTGGATGATGCCNGCNGAYGTNCARMGNGCNGARGCNGTNGAYGARMGNYTN TCNAAYATGGARCAYCAYYTNAAYATHGTNGAYGAYGGNGGNGAYATHTAYAARMGNATH AARGCNYTNGARGARMGNATHAGYTTYYTNGARGGNGTNTCNCCNGARTAYTTYACNMGN GGNATHCCN---------------------------------------ATHMGNCCNATH GTNCCNATHAARCARAAYACNGGNGARATHGGNGGNCAYCCNACNAAYGTNATHGTNAAY AARTTYGARGAYCAYYTNTTYATHATHGTNACNCARTAYCARAARYTNGGNACNATHGTN GARGTNTCNMGNGAYGTNGTNAGYGAYGARGTNCARGGNCCNATHCCNATGTTYTCNACN AGYGTNYTNYTNGGNAARGAYGARCCNYTNACNCAYGTNATGGCNAARACNATHGTNGCN GCNYTNAAYCCNCCNATHCCNGTNATHYTNAGYYTNGCNCARAARGARACNTCNTAYGAY TCNATHCARGCNATHATHGARYTNATHAARTCNTCNYTNATGGCNACNAAYATHCAYTTY GARGCNMGNMGNMGNCARMGNGTNATHGAYMGNGCNTGYCARGCNMGNAARGAYATGGCN YTNGGNCARACNTCNGAYMGNGCNGCNCCNGTNGARGARGGNCCNAAR------CCNGAR ACNATHATGTGYACNGAYCARGGNCARTTYTAYCARACNMGN---AGYATHCAYGTNTGG ACNGGNTCNGARMGNAAYMGNMGNACNTAYGAYMGNAGYMGNGARGGNCCNGTNYTNGGN AGYTCNTGGMGNCARYTNGARMGNGARATGAAYTTYMGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGCCNAAR TAYTAYGARGAYGTNGARGARAARCCNACNMGNACNAARTAYGCNTGYGARGGNATHMGN GAYGAYYTNYTNGAYTGYYTNYTNAARAGYGAYTGYTGYAARAARGARAARNNNACNCCN MGNGARTGYATGAAYMGNATHGGN---------GAYCCNTCNGTNCCNAAYGARTGYCAR YTNYTNMGNCAYTCNTTYTTYGTNTGYMGNMGNTCNATGYTNGAYATGMGNACNMGNTTY MGNGGNMGNAARGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GCNTCNCCNCARAARAARTCNGGNAGYTCN---GGNYTNTCNACNAGYGAR GGNGCNGGNATHGGNYTNYTNGTNATHGTNTGYGTNGCNGGNGTNGCNATHGGNATHTTY GCNGTNTAYMGNMGNAGYAAYATGACNAGYMGNAGYTTYAARGCNTTYYTNACNGGNGGN GTNMGNTAYAARACNTAYACNAAYGCN--------------------------------- GARGAYAARTCNMGNAARAAYGCNATHCARGCNAARATHAAYMGNGARAARAARAARGCN TAYATHAAYACNYTNGARGARGARACNAARTCNYTNAARAGYGAYAAYACNAARYTNAAR TCNGARAAYCARAARATGAARAGYAGYATHTCNGARYTNGARGARGARGTNGARTAYYTN AARTCNGTNYTNGTNAAYTCNAGYTCNYTNTCNGGNYTNYTNAARAAYATHTCNAAYGTN CCNGARGTNAARYTNTCNGCNACNGTNGCNGGNMGNAARMGNTCNGTNGCN------GAY GAYCAYAGYTAYGAY---TTYGAYTCNGCNCCNGTNAARMGNGCNMGNMGNATHCARGAR AAYYTNAARAARGCNGGNGTNTGYYTNCAYGTNAAYGGNTCNTCNGCNAGYYTNGARTTY TGYGCNCAYTGYTCNAARYTNGCNCAYAARACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY GARCAYGGNYTNGTNAAYCAYATHCAYYTNATGTGYGAYMGNCAYYTNGAYCARYTNATH ATGTGYTCNYTNTAYYTNATHGCNAARGTNACNGAYAARGAYYTNACNTTYCARAAYATH ATGAARTGYTAYMGNYTNCARCCNCARGCNCARAGYCAYGTNTAYMGNAGYGTNYTNYTN CARGAYMGNCARMGNCAYAGYTCNGGNAGYAGYGAYGGNAGYAGYAARAGYAGYAGYACN YTNCCNTCNTCNGTNGGNGCNCAYGTNGAYCAYAGYAAYCCNGGNGGNACNAGYTAYGGN GTNCAYGCNAGYCAYACNTGGTCNCAYAGYGGNGGNAGYAARACNACNGTNTCNGGNGGN TTYGAYCAYAAYTCNCAYGGNGGNAAYAGYGGNGGNATHAGYGTNACNCAYCAYTTYGGN AARMGNATGMGNGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GCN TCNTCNAGYGGNGGNATHTGGYTNAARCAYCCNGGNMGNYTNGGNCCNATHTCNGTNTAY GGNGCNGGNTGYTGGGCNCARAAYCARTCNTCNGAYACNAARCCNGGNGTNGCNGTNGTN ACNTCNGGNTGYGGNGARCAYATHATGCARACNATHYTNGCNAARACNTGYTCNGAYGGN ATHMGNTCNCCNGGNAAYYTNTCNCARTCNYTNCCNCARGTNTTYAARAGYGAYTTYYTN GARTCNGARTTYYTNTCNACNAARCCNGARAARCAYGGNGGNGTNYTNGCNYTNAARTTY AGYGARGCNCCNGAYGGNAARGARGTNGARYTNGGNTGGATHCAYTCNACNAAYAAYTTY TGYTTYGCNTTYATGGGNGGNGAYCARAARACNCCNAARGCNYTNATGTCNTCNYTNGAR GARCAYTGYAAYCCNGGNAARTCNTAYACNATGGGNGGNCAYGTNGTNTTYYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARTTYTGYTAYGGNAARTCNGTNMGNCARTAYCAYATG GARGAYGGNGCNATHAARGGNAAYGTNATHCAYYTNGGNTTYTAYGARAGYGAYTTYGAY TGGAGYAAYGARACNGCNAARGARGARMGNYTN------AARATGAGYYTNGCNAGYTAY CAYTCNCARTCNTTYACNCARGGNGAYAARTGYGAYYTNACNGGNCARCCNMGNATGGTN GARGTNMGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GTNATHMGNATHATHATHAGYTGYGCNACNGGNYTNYTNTTY GGNATHGCNYTNGARAARGGNMGNGTNTTYGARCCNCARGTNATHMGNGAYCARYTNYTN YTNMGNMGNTTYGGNATGYTNAARATGTTYYTNTCNGCNTCNGCNGTNGGNATGATHTCN TTYTCNTTYYTNTAYGGNATGCCNCAYACNATGMGNAARATGGGNYTNGCNATHCARAAY TTYCCNGARAARCCNYTNGTNAARACNGGNYTNGGNGTNYTNATHGGNGCNGCNYTNYTN GGNAGYGGNATGGCNATHTCNGGNGCNTGYCCNGGNACNTCNATHGTNCARYTNGGNGCN GGNGTNGARAAYGCNTAYATHACNATHYTNGGNGGNYTNTTYGGNAGYYTNGCNTAYGCN ATGACNCAYGCNGAYYTNTTYTCNACNTAYAARACNAARYTNYTNCCNAARTAYTCNATG YTNCAYAARTAYYTNGARYTNCCNTAYTCNTCNATHGCNATHCCNYTNTCNTGYGTNYTN GCNGGNGCNGTNTTYGGNYTNGARGTNTTYTCNCCNTGGCAYAARGARATHGAYTCNTCN YTNGTNACNGARGGNATHATGAARGCNGGNGCNTGGCCNCCNTTYATHGCNGGNATGATH ATHGGNACNYTNCARGTNCCNATHGTNYTNACNAAYGARGAYACNYTNGGNTCNGCNTCN GCNTAYGTNACNGTNYTNTCNTAYYTNTGGCCNTCNCCNTAY---------ATHAAYAAY GARGARGAYTAYYTNAARAARTAYMGNTCNGGNCCNGGNAAYTGGTGGCARGTNYTNTAY ATGACNAGYGCNATGGTNGGNGGNGCNYTNTCNGCNACNGCNTCNGGNACNATHGGNACN GTNCCNGGNYTNCCNTGGCAYCAYGCNTTYGGNGGNGGNTTYYTNATGYTNTTYGGNGCN MGNYTNGCNGGNGGNTGYACNAGYGGNCAYGGNYTNTCNGGNTTYGGNYTNYTNTCNYTN ACNTCNTTYATHGCNGTNCCNGCNATGTTYGGNAGYGGNATHGCNACNGCNTTYTTYATG AARTAYGTNGTNGGNGTNGARATG------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNATHGGNAARYTNCARGARMGNGTNGAR GARGARGAYAARAARMGNAGYAARYTNGARTCNGAYTAYCAYCAYYTNAARGGNAARGTN CARTCNYTNCARGTNGAYYTNGAYAAYAGYGARGCNGTNCARMGNGAYTTYGTNAARYTN TCNCARTCNYTNCARATHCARYTNGARAARATHMGNCARGCNGARACNGARGTNMGNTGG ------------------------------------------------------------ ---------------ATGTTYMGNCCNGAYAARGAYYTNCCNTCNGGNATGYTNCCNTCN CARCCNTCNTCNCARATHTCNGGNTTYAAYGGNAGYACNAAYTTYTAYGGNCARGGNAAY YTNTCNYTNCARCAYMGNGCNATHGGNGCNAAYCAYTTYMGNGGNGGNAAYAAYACNGGN CAYATHACNCCNACNAGYATHAAYACNGGNTTYCCNYTNGGNYTNCAYCARCCNCARCAR CARCCNCARCARCARCARCARCAYTCNCCNAAYAGYYTNGCNGCNATHGGNTCNMGNAAY GTNYTNAAYGTNCCNAGYCARGGNGGNCARCARAGYYTNGTNAAYATGCARAARMGNCCN TTYAGYTCNTCNGGNCCNATGCCNAAYTTYGCNACNTCNTAYGGNTTYGGNGGNTCN--- TCNATGGARCCNCAYCCNGCNATHGAYYTNTCNGAYTTYCCNACNYTNAGYAGYMGNTCN TCNGCNACNCCNAAYCCNYTNCCNTCNACNMGNAAYTAYGTNGGNATGGTNAGYAARCCN GCNCARGAYTCNGCNCCNGARTTYAAYATHTCNCARGARGARTTYCCNGCNYTNCCNGGN TCNCARAAYCCNCCNGTNCARTCNGGN---TCNGARTAYMGNGGNMGNGGN---MGNAGY AGYAGYTGGMGNGGNGGNCCNCCNMGNGGNGGNGGNTTYMGNGGNGGNMGNGGNGGNTAY ATGATHGAYMGNGARGGNGGNMGNGGNGGNGGNGGNMGNGGNMGNGGNGGNTTYTCNMGN GGNMGNGGNGGNCCNCCNMGNAGYMGNGAYGAYATGTCNCCNCCNMGN------ATGTCN MGNAGYTAYGAY---ACNGAYMGNGTNMGNGGNCCNCCNCCNAGYMGNMGNCCNGAYMGN TAYGARGAYAGYTTYGAYMGNGCNCCNCCNTCNATGMGNATGAARGAYATGTAYTCNTCN CCNCCNMGNGAYTCNGGNMGNAGYTTYGAYMGNCAYTCNCCNCCN------CCNMGNMGN GARMGNGAYTAYCCNCCN---MGNCAYAGYGAYCAYATGAGYTCNMGN---GAYTAYYTN TCNCCNMGNAGYTAYTCNCCNCCNMGNGAYTCNGGNTAY---AGYTCNTAYAARGAYTCN TAYAGYTCNGCNCCNMGNGARGARMGNMGNCCNATHMGNGAYTAYCCNCCNCCNMGNGGN TCNAGYGAYTAYGAYAGYCAYMGNGGNAGYAGYMGNGAYTTYMGNGAYGCNCCNMGN--- GGNGGNGAYTAYAGYTCNMGNGAYTAYCCNCCNTCNTCNTCNMGNAAYGGNGAYTTYMGN GARTCNYTNAGYAGYMGNGARTTYMGNGAYGCNCCNMGNGGNGGNGAYMGNTAYGGNAGY GGNGGNGGNMGNGGNGGNAGYAGYMGNGGNMGNTCNMGNTTYGARGAYAGYMGNGGNCCN CCNCCNMGNGARTAYAGYTCNMGN------GGNMGNGGNGGNGAYMGNGAYGAYGAYMGN GGNAGYMGNGGNTTYMGNGGNMGNGGNGCNCCNMGNGGN------MGNGGNMGN---GAY TTYTCNGGNGGNMGNGGNGGNGAYMGNMGNTCNCCNAGYMGN------GARGGNGCNGGN GGN---------AARMGNCCNMGNYTNGAYTCNGGNGAY--------------------- ------------------------------------------TAYMGNMGN------TCN ATHYTNGARACNAGYATHGGNAARGAYGCNGAYTGYGARMGNGTNTTYAARMGNTTYACN TAYAARTGYYTNCARATHATHGTNCARTCNMGNATHGARMGNCCNGTNYTNCARGGNAAR GAYACNTCNAAYGAYTAYTTYAGYATHAAYYTNTCNGAYAGYGGNYTNATHGAYGARCAR ATHAARTAYACNYTNGARGGNATHAARTCNTTYCCNGTNAARGAYMGNCCNATHTGYGTN GARATHGCNYTNMGNACNAAYGAYGGNGAYCAYATGTTYYTNGARACNTGGGAYATHAGY TTYAAYYTNAGYAGYYTNGAYATGTCNGCNAGYAARGTNCARCAYATHTTYACNMGNATG GGNYTNACNYTNAARTCNYTNATGGCNGCNACNMGNGCNACNCCNGCNTAYMGNYTNGCN AARAAYCARGGNGARAARGGNGGNGGNTAYAARYTNAAYTAYMGNTTYTAYYTNGGNCCN CCNAARACNCAYATGYTNGGNGARGGNTTYAARAGYATGMGNGCNGGNGCNGTNCCNTCN GCNTTYGGNYTNYTNAGYGTNGGNGTNTCNTAYMGNACNAARYTNYTNYTNTCNCCNGAY ACNACNGCNCCNTCNTCNAGYGTNATGCARGTNACNGAYGAYTAYTTYATGAARGARAAY MGNGCNCAYTCNAGYTGYCARGGNTAYTCNGAYCCNAARCCNTGYCAYTCNTCNGTNMGN MGNMGNCCNTCNYTNTCN------------------AGYCCNGARCAYATGGCNGCNACN CCNTAYAAYTAYACNATHTCNCCNTCNTCNCARGGNACNGAYGARGAY---ATGATGTCN AARYTNTCNGCNGAYAGYAAYCCNYTNCCNTGGCCNYTNGCNAGYATHYTNAAYATHGAY GARYTNCCNGARCCNGCNGTNGGNGCNTTYTCNGTNCARMGNCCNAAYCCNYTNMGNGTN GARGARAAYGAYYTNCCNTTYGARGGNYTNATGAARMGNAGYATGATGGCNMGNYTNGAR CARAAR------------CARMGNCARGARYTNAGYGARMGNACNATHGAYAGYGGNTTY GARMGNTCNAGYGARYTNMGNCARCARGGNACNAGYGARGAYGARAARGARAAYYTNGGN GTNYTNAAY---------AAYAARATGCCNTTYGARGAYGAYTTYGTNATHGTNGAYCCN CCNTTYGCNTGYGAYGAYGAYCCNMGNGAYGTNAARTCNTTYYTNGGNGTNATGTTYMGN GCNCCNCAYYTNTAYGAYGTNTCNGAYACNMGNCCNACNATHAAYGAYTAYYTNAAYGAY GTNGGNCARATGGTNTCNMGNYTNGARGARGAYATGCCNATGYTNGAYGARTTYTGYCAR TCNGTNATHGARTTYACNAGYACNGARGAYGARGAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TTYGCNGGNMGNGGNCCNGGNTGYMGNGTNATGTTYTGYMGNGAYGCNTTYTAY CAYTCNGARATHGAYGAYYTNGAYATHMGNATGGAYCAYATGATGCCNACNYTNAARAAY MGNCCNMGNGGNAARAARAARAARGARYTNTGYMGNAARGAYTCNCARCAYGAYTCNGAY AGYACNGARGARYTNTTYGCNAAYATHGCNCCNACNATHTCNTCNTCNTCNMGNCCN--- ------------------------------------------------------------ ---------------------------------------------------------GAR ACNAGYMGNTCNYTNAARGAYTTYGARATHYTNACNMGNATHTCNGARYTNATHCCNYTN GCNAARTCNATHYTNATGATHAARAARATHATHTCNGCNTTYGCNMGNAARYTNGTNAGY YTNYTNGARGARMGNAAYGTNYTNCAYAAYGCNGARTCNTCNCARAAYATHYTNGARTGY YTNAARAARTTYTGGTCNYTNTGYTCNMGNCARCARAAYGTNATHTCNTCNTCNMGNTGY TTYGGNAARTGGCAYCCNATHYTNYTNGARGARATHACNCCNYTNGCNTCNYTNTTYATH GAYYTNTTYATHTCNGCNCAYGGNCAYTGY------AARAAYAARATGAARTGGTCNAAR AARYTNTAYAGYTGGYTNAAYTTYGAYYTNCCNGAYMGNGCNATHMGNATHGCNYTNYTN GARGCNGARGGNCAYGGNAARGARGGNGCNGARATHGTNGGNCCNYTNYTNAGYCAYATH YTNMGNMGNAARACNAAYGAYYTNTCNGAYGCNGAYTAYYTNYTNCAYTTYYTNYTNYTN AARAARTGGCARGGNYTN---GCNGTNGTNTCNGAYYTNYTNGARGARTCNAARYTNATH AARGCNCCNCCNACNTTYYTNCCNTGGGTNAARACNTAYYTNAARGAYGGNTGYCAYTTY ATHCCNGARGAYACNACNATGATGGGNGCNTCNGTNAGYCARTTYYTNATGGAYYTNAAY ACNTGYGAYGTNYTNGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNGAYCCNTGYCCNGTN ATHCCNMGNGGNTTYCARATGTCNCARTGYACNGCNAARAAYTTYACNTGYACNAGYAAR MGNCARTGYATHYTNTCNGGNCARAARTGYGAYGAYAARGTNCARTGYCAYGAYGGNTCN GAYGARAGYGGNTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GCNGARAGYGTNGAYGAYATHTGGTCNATHAAYGAYGARCARMGNGARTAYTAYATH ATGCARCCNGAYYTNAAYAAYGTNATHACNGGNCCNGTNGCNAARCAYTTYTTYGARAAR TCNAARYTNCCNGTNATHGARYTNTCNAARATHTGGCARYTNTCNGAYYTNAAYTGYGAY GGNGCNYTNTCNATGGARGARTTYTGYATHGCNATGCAYYTNGTNGTNYTNMGNMGNAAY GARATHGARYTNCCNGAYMGNYTNCCNYTNGAYGAYGGNAARCCNGTNGTNGARAARGAY GARMGNGGNATGCCNGTNTTYAARGTNCAYTTYAAYATGAARGAYTAYMGNCCNGARGAR GTNAAYGTNAARATGGAYAGYAGYAARATHATGGTNTCNGCNAARCAYGARGARAARTGY AGYGGNTCNACNGTNAGYMGNGARTAYAAYMGNGARGTNAAYGTNCCNGTNGARGTNGAY CCNYTNGCNYTNCARTGYYTNTTYCARCCNGAYGGNGTNYTNGTNTTYACNGCNCCNYTN CCNGCNCCNAARTAYGAYGCNATHAARGARGCNTCNCCNGTNCAYCAYGCNCCNCARAGY ACNTGYTCNTCNTCNTCNTCNAARTTYTCNGARCAYCCNGAYATHATHGTNCCNACNTTY MGNGCNCCNCCNGAYATHAAYAARYTNYTNGAYACNCCNGCNTCNATHCCNCCNYTNCAY TCNTCNCCN------ATGCCNAARCCNCCNCCNTTYACNAAYYTNAGYTCNACNTTYCCN AAYGGNCCNATHTTYACNGAYTCNTCNCARCARATHCARYTNAGYGTNCCNACNGTNACN TCNCAYGAYGGNAARTTYCARYTNACNATGCCNATHGAYGAYTTYAARCCNGARGARYTN ACNGTNAARACNCARGAYAARAARGTNATHATHTGYGCNAARMGNGARGTNYTNAGYGGN AGYMGNAAYCAYACNATGGARATGAAYMGNGARCAYAGYYTNCCNGAYAAYGTNGAYCCN YTNACNGTNAARGCNTTYTTYACNGAYACNAAYATGYTNATHGTNGARGCNCCNYTNYTN MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------GAYCCNTCNMGNCCNCAYACNATHAGYTCNGCNTAYGARAAR GGNCAYGGNMGNCCNGCNYTNAARGCNGAYATGTTYGARCCNCCNGGNGGNGCNGTNGAR ATGMGNCCNMGNCCNGCNMGNCARGAYMGNCAYCAYTCNGARTTYACNGAYGAYGARATH MGNCARGARYTNGCNCARYTNGGNTAYCAYAAYGTNCCNCARGAYAARYTNGARGARTTY AARAARGAYYTNATGACNYTNATHTCNAARGARMGNAGYAARTCNAAYTCNYTNAAYAGY AGY---------------TGYAAYACNGARCCNGAYGGNGGNAGYAARCCNTCNCARGAR TAYCAYCARTTYGCNGAYGARAGYTTYTCNAAYAAYGGNGAYCARTGGGTNGGNCARTCN MGNTTYATHGARAAYTGGGAYTAYMGNGGN------------------------------ ------------------GARMGNGAYATHGGNCARMGNCCNCARACNGCN--------- ------------------------------------------------------CCNGGN GARMGNTAYMGNGAYTAYGGNGARMGNAAYCARAGYTGYCAYYTNGAYGAYGTNTCNGAR TCNGGNTCNGARAGYMGNTTYATGAARMGNAARACNGCNMGNAARACNCCNAGYGGNTGY MGNYTNGTNGAYGARTCNTTYACNGAYACNGARTCNGGNGTNTTYGARATHTAYGARAAR ATHAARAAYYTNGCNATGMGNGARTGYGARTGYGGNAARACNAARCCNAARTCNGGNGAY GTNGARCCNCCNTAYMGNATHAARGGNAARGTNAAYAARACNCCNTCNGTNATHMGNAAR YTNGARCCNCCNCAYACNMGNAAYYTNGTNAARACNGAYGTNAAYGARMGNCAYAARATG TAYAARGARGCNTGGAARACNCARCCNGCNATHGGNGARGAYCAYMGNATHCCNYTNMGN AARGCNATGCAYTCNAARYTNATGAARCAYGARCARGTNMGNATGAARTCNAARGTNTAY ATHCCNAAYYTNTAYACNCCNCCNCAYGARAARYTNMGNAARGAYGTNMGNTGGAAYGTN MGNGARGCNTTYGARAARTAYGARYTNCCNACNCAYGGNTTYTAYCAYGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CAYGAYCCNMGNATHTCNACNCAYGAYCAY TAYTAYMGNGGNATGYTNYTNMGNTCNGGNAGYCAYATHAARGGNGCNTCNMGNGCNGCN ACNATGYTNYTNATHGARATGGARTCNAARMGNMGNMGNMGNMGNGGNTGYTGYYTNTGY ATHATHCCNTTYYTNYTNYTNYTNCCNYTNGCNYTNYTNGCNGGNCAYTAYGCNAGYCCN CCNGGNYTNACNTCNGAYCARGTNMGNGCNATHGTNCARGCNATGATHTCNGCNCARATG GGNTCNACNCARACNGARATHGAYTCNCAYATHAAYTCNGTNTCNGGNATHYTNAARGAR GAYATHTCNGGNATHAARACNAAYYTNGTNGGNYTNCARGCNCARATHCAYGAYGCNATH MGNGARACNCARGTNGTNGCNGGNGTNGARAARACNAARGCNTCNGTNCARAGYACNAGY CARGARCARGGNACNGARTGGYTNGCNGCNTCNCARATGYTNGARACNAARTTYYTNGAY YTNMGNAAYGAYGTNAAYCARYTNGCNAAYCARAAYACNGCNYTNGTNGCNATGYTNAAR TCNTGYTGYCARAAYAAYACNGCNYTN---GCNACNGTNMGNGCNCAYATGGTNTCNATH YTNTCNGARYTNGGNGARGAYGAYAARGAYTCNGCNYTNGGNGGNYTNATGGCNTGGATG CARGARAARTAYGTNGGNMGNGCNGARYTNGAYGARAARYTNTCNYTNGTNGCNGCNAGY GTNACNGARAAYYTNCARTCNYTNYTNGCNGCNAARYTNGCNGCNGARACNCARAARACN ATHGTNTCNGCNAGYATHGAYGARYTNGCNGTNAARTCNATHGTNGARGARGCNYTNGTN CARTTYAGYGCNGAYMGNGTNGGNATGCCNGAYTTYGCNYTNGARTCNGCNGGNGGNAGY GTNYTNAGYGTNMGNTGYTCNGARACNTAYTAYMGNAARACNGCNYTNGTNAGYGTNTTY GGNGTNCCNYTNTAYTAYACNTCNAAYTCNCCNMGNACNGTNATHCARCCNAAYGTNCAY CCNGGNGARTGYTGGGCNTTYAARGGNAGYTCNGGNTTYATHGTNATHCARYTNTCNCAR CCNATHCARCCNACNGGNTTYACNYTNGARCAYATHCCNAARAGYYTNGCNCCNTCNGGN ACNATHGAYAGYGCNCCNAARTCNTTYACNATHYTNGGNYTNAARTCNGARGARGAYYTN GARGGNAGYAAYATGGGNAAYTTYAGYTAYYTNGAYAAYGGNAARCCNATHCARCAYTTY CARGTNCARACNCARCAYCARGGNGTNTTYCARTTYATHGARYTNMGNGTNYTNACNAAY CAYGGNAAYCCNGARTAYACNTGYATHTAYMGNGTNMGNGTNCAYGGNYTN--------- MGNGARTAYCARTGYCCNTCNMGNYTNACNGARAARTTYTCNGARATGGTNATHGTNGAY AARCARACNAAYAARTCNGAYTAYCAYYTNCCNATHGCNACNAAYATHATHAGYTCNYTN ATHGAYCCNGARCARAAYAAR---ATGTCNGARATHAARGAYCCNGTNTCNCARCAY--- ------ACNCCNGCNGCNAARGARGCNAARATHATHATGMGNATHMGNCAYAARAARATG AARAARCAYAARYTNAARAARYTNMGNAARMGNATGTAYTTYYTNTGGMGNAARCARAAR YTNACNMGNAARGGNAARMGNGAYACNATHTAYTGGAARGGNATHTCNGAYATHAARAAR GARGGNGAYGAYTTYGAYGCNGARACNTTYGTNAARGARCARYTNCAYAAYGCNMGNMGN GGNGGNTAYCAYATHAAYGTNTTYGARTCNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATHGGNTTYAGYTTYATHTCNGCNYTNYTNTTYACNATHACNTAYATGGTNATGGAR GARYTNTGGCAYGARAAYTCNYTNTTY---AARGARAARGTNAARACNCARATHATHGCN GCNYTNAARTCNGCNGCNYTNYTNYTNATHYTNAGYTTYATGTAYCAYTTYATGGCNGTN YTNTTYGGNGCNCCNGTNYTNATGYTNGTNTCNGARACNTAYCAYTTYGCNATHYTNYTN ACNGTNYTNACNGGNYTNCCNATGTGYGCNGTNGCNGGNCCNMGNYTNGAYAARTGGATG GAYATHYTNACNACNGAY---MGNGARCCNGGNYTNCARACNGTNGTNTAYYTNACNACN GTNGGNGCNYTNYTNGGNGCNTGGGTNGGNGCNATHCCNATHCCNYTNGAYTGGGAYMGN CCNTGGCARAAYTGGCCNATHAGYTGYTCNATHGGNTGYGTNTCNGGNTAYTCNGTNGGN YTNTTYATHGCNTCNGTNTAYYTNCCNCAYCARTTYAARGCNYTNTTYAARCARAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CAYTCNATHGGNTGYTAYTTYATHYTNAAYGTNYTNGAY AARYTNCCNATHCAYCAYATHCARMGNTCNTTYTTYYTNTTYCCNACNATHGARMGNATG GCNYTNTCNCCNAAYGGNYTNAAYYTNACNCCNGTNTTYMGNTAYYTNMGNTGGATHATH GTNYTNYTNGCNTTYTTYTGYATHYTNATHCCNMGNACNYTNMGNCARATHATHGTNCAR TTYATHTAYMGNAARGTNGCNTAYCCNCCNTGYATGATGCCNTCNATHATGAAYACNGTN AAYCCNTGGACNGCNAAYTTYTCNACNTTYYTNGCNAARACNGARATGAAYAARGTNACN GCNYTNCARAARGAYYTNGTNGGNAARCAYYTNGAYAARYTNAGYYTNTAYTAYGGNGCN AARGAYYTNTGGTGYCCNGTNGARTAYTTYAAYGGNATHATGGARGARTTYCCNATGYTN GAYGCNMGNYTNTGYGARYTNAAYATGACNCAYGCNTTY--------------------- ---------------------------------------------MGNMGNCAYGGNTTY TCNTGYYTNACNYTNGAYGCNACNMGNTCNMGNYTNTTYGCNAGYTGYACNGAYGAYAAY ATHTAYGARTAYAAYATGAARTCNGCNGARGAYAARCCNGTNCAYMGNTTYMGNGGNCAY AARAAYTCNACNTTYTAYGTNAARACNGCNATHAGYCCNTAYGTNTGGCARATHAAYAAR MGNGARGCNCCNCCNYTNYTNYTNAARGCNCAYGAYAGYGARGTNACNTCNGTNGCNTGG TGYCCNATHGAYYTNACNAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TAYGGNACNAARGTNYTNGGNATGGARACN GTNCARAGYCAYGCNTCNGCNGCNGARAARMGNGCNGTNAARCARGGNATHGCNTGYGAY GGNGTNAARAGYYTNCARTGYCAYYTNGARGAYAARGARGARTCNTAYAARGCNTTYGTN GGNAAYGTNGARTCNGTNTTYCARACNYTNAARTGYGAYTGYGCNGARMGNYTNACNGGN GARACN------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNCARCCNTCNTTYGARAARTTYCCNYTN AGYGAYYTNGGNAARMGNYTNCAYACNCARCAYACNCARGARAARGGNCAYCCNTTYATH ACNCCNTTYACNYTNMGNYTNGGNGCNCARGARACNMGNAGYMGNTGG------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNTTYTAYGARAARYTNAGYAAY MGNGTNAARYTNACNACNAARAAYATGTGYMGNCAYYTNGAYATHYTNTCNGARYTNTTY TCNAARCARTGYAAYYTNGTNYTNGCNCARMGNATHMGNMGNTCNTAYCARATHYTNYTN YTNTAYMGNAAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNTAYGGNGARCAYYTN YTNAARGARAGYTCNCAYAARAARAARGAYGAYGARATHAARAAYTGYCAYMGNGARGTN GTNGARGTNAARTCNYTNYTNAARCAYCCNGARAAYCCNGAYTGGGARACNATHGTNGAY AARGTNGAYTTYAARGTNTGGMGNTAYAARATHCCNAAYACNACNYTNTTYAARTAYMGN GTNYTNGGNCAYTTYAARGAYATHCCNGCNMGNGCNTTYTAYAAYACNCARGTNGAYGTN CAYTAYTGGAARGAYTGGGAYAAYCARACNATHGAYGTNAGYATHATHGAYMGNGAYGCN AARACNGGNTCNGARGTNATHCAYTGGYTNTAYMGNTTYCCNTAYCCNATGAAYCCNMGN GARTAYGTNTAYGTNMGNMGNTGYACNATHTTYCCNGARAARAAYGCNATGATHATHACN GCNMGNGCNACNAARCAYCCNACNTGYCCNTAYMGNTCNAARAAYGTNMGNGTNGARACN TAYATGTCNCARATGGTNATHACNCCNTAYACNTTYTTYGAYGARGAYGGNTTYTCNTAY ATHATGTCNTAYTGYGAYGAYCCNCARACNAAYTTYCCNCCNGTNTGGTAYAAYTGGATG GCNAGYGCNGGNGTNCAYGARTTYYTNGARMGNATGCAYMGNGCNGCNYTNAARAARCAY GARAARAGYGTN---GARAAYGCNACNAAYGTNATGGAYAGYGGNGCNCARACNYTNTAY CCNGGNATGGTNCAYATGYTNYTNMGNYTNAARGARGTNGTNCARTGGACNMGNATGACN GCNYTNGARYTNATGYTNCAYYTNGTNTCNGTNYTNATGTTYTCNYTNYTNGTNGCNACN AARGTNGARGGNGAYGTNACNGTNTCNTGGCCNGTNATHTTYTCNCCNYTNTTYATHTGY GAYGGNYTNAAYGCNTAYYTNTGYGTNATHATHTTYGTNMGNCARTAYMGNGARTAYGAR YTNAARCARGCNTGYYTNMGNYTNTCNAAYTCNYTNTCNGTNATHGCNYTNATHTTYACN TTYAARYTNYTNYTNTGYCARAARYTNGARAAYGGNGGNYTNAAYTGYTCNGARGTNTTY GCNCCNGTNTTYGTNYTNTCNCARGTNTTYATGTTYMGNGCNTGYMGNATGCAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CCNGTNGARAAYGARGARGAYGARGTNAARGARGARGAYGAYYTNTTYTCN GAYGCNAARGARAARACNTCNTCNCCNGAYACNTCNAGYCCN------------TTYAAY GGNACNGAYGAYAAYCARTTY---GGNAGYGAYGARGARGARGAYGAYYTNTTYAARGGN GGNAGYTCNGARATHAARYTNGARTCNGAYGAYGARGARGTNCCNGAYGTNAAYAAY--- ---------------AGYCARTCNGCNGARGCNGARGARGARGARGARCCNGCNGCNAAY ---------GCNTCNGCNAARAARGARGTNACNCCNGARATHTCNGTNTCNGARGTNATH ACNGCNAARACNAARATHGCNGCNCCNTCNYTNAARACNGAYGAYGTNCCNGARGARAAY GAYGAYGARAARGARCARTAYGARYTNGAYATHAARATHACNGARAAYYTNAARATHGGN GAYGGNATGTCNGCNTAYATGGTNTTYAARATHGTNTCNAARACNACNAAYCCNGCNTTY MGNCAYCCNGARAAYGCNGTNYTNMGNMGNTTYAGYGAYTTYYTNGGNYTNTAYTCNAAR YTNGCNGARAARCAYGTNCCNYTNGGNATHATHGTNCCNCCNGCNCCNGARAARAGYGTN ATHGGNATGACNAARGTNAARATGTCNAARGARGAYACNGGNTCNATHGAYTTYATHGAR MGNMGNAARGCNGCNYTNGARMGNTAYYTNATHMGNACNGCNGCNCAYCCNYTNYTNGCN GCNGAYTCNGAYTTYATHGARTTYYTNGARAARGAYGGNGAYYTNCCNAARGCNACNAGY ACNTCNGCNYTNAGYGGNGCNGGNGTNATGMGNYTNTTYCAYAARGTNGGNGARTCNYTN GARAARATHACNYTNAARGTNGAYGARAGYGAYGARTGGTTYGARGARAARCAYCARCAR ATHGARGCNYTNGAYYTNCARYTNAARAARYTNCAYATHAGYYTNGARACNYTNGCNGCN CAYMGNMGNGARYTNTCNGGNAGYACNGCNACNTTYGCNAARAGYGCNGCNATGYTNGGN AAYGTNGARGARCAYACNGCNYTNTCNMGNGCNYTNTCNCARYTNGCNGARACNGARGAR AARATHGARYTNGTNCAYMGNGAYCARGCNGARGTNGAYTTYTTYACNATGTCNGARYTN ATGAARGAYTAYGTNGCNYTNATGGGNGCNGTNAARGGNGTNTTYCAYGARMGNATHAAR ACNTAYAARCARTGGAARGAYGCNGARACNATGYTNGGNAARAARMGNGARAAYAARGCN AARYTNGARATGCARGGNAARGCNGAYAARYTNTCNCARGCNMGNACNGARATHACNGAR TGGGARCAYAARGTNGARAARGGNCARGARGAYTTYGARAARATHTCNAARACNATHMGN AARGARGTNGCNMGNTTYGARAARYTNMGNGTNTCNGAYTTYAARACNAAYGTNATHAAR TAYYTNGARGTNYTNATGGARAAYCARGARAARYTNATHAARTAYTGGGARACNTTYYTN CCNGARGCNAARGCNATHGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARTGYCCNTAYGARGGNTGYGGNAARACNTTYCCNTTYCCNACNGTNYTNMGNMGNCAY ATGAARGTNCAYCARGGNTAYACNTGYGARGARGAYGGNTGYGGNGARGTNTTYGARACN TAYYTNAARYTNMGNAARCAYAARGCNGTNGAYCAYGGNCCNGAYYTNATHTGYMGNCAR TGYCARACNCARTTYAARTCNMGNCARACNYTNGTNCARCAYYTNAARACNCAYYTNTTY GTNAARGARGTNTTYGCNTGYACNGARCCNGGNTGYGARMGNACNTTYYTNTAYAARAAR AAYYTNACNCARCAYATHMGNTCNTAYCAYYTNGGNGARMGNGTNTTYGTNMGNAARAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARGGNCCNMGNGARGARYTNATHAGYACNGCNATGAARTTYYTNCARAAYCCNAARGTN ATGGGNAGYCCNYTNCAYCARAARAARGCNTTYYTNACNAARAARGGNYTNACNCARGAR GARATHAAYYTNGCNGTNGARMGNTCNGGNGTNACNGAR------ACNACNGGNGTNGCN ATGGAYCARGCNMGNCCNCCNCCNCCNGGNTAYCARCCNGGNATGATG------------ ---GTNCCNTAYAAYCARATGYTNCCNCCNATHCCNCCNCARTCNMGNTGGGCNCARGTN MGNGAYYTNACNYTNACNACNGCNGTNGTNGCNAGYATHTCNTAYGCNATGTAYCAYYTN TAYAARACNTAYATHGARCCNYTNATHMGNGGNAARACNGCNCARGARAARMGNYTNGAY MGNYTNGARYTNCARGTNGAYGARATHCAYAARTCNGTNAAYGAYTCNYTNTCNGAYATH AGYMGNACNYTNGCNGCNATHCARYTNACNATHAAYAAYCARAGYCARCARCCNTCNGCN AGYCARACNGTNGGNMGNGGNATHACNGAYYTNAARGCNGAYATHTCNTCNYTNMGNAGY YTNYTNYTNAGYAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNAAYTAY ATHGAYAARGCNYTNAARATHGARTCNGAYAGYGCNGARCAYYTNTGGYTNMGNGARAAR YTNTTYMGNCARTGYMGNGTNYTNGARGARCARAAYACNGCNAARATGAAYATHGAYGAR AARCARATGAARTTYCCNTCNATGAAYGARGTNCCNMGNATHTCNGGNAARACNYTNAGY GTNGCNAAYTTYGARAARAAYTTYYTNMGNGCNAGYAARCCNGTNATHATHACNGAYATH GTNTCNGAYATGACN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARCARMGNTCNGTNATH GAYTTYGTNGTNTTYGARGGNNNNACNYTNATHAAYATHCAYAARMGNYTNGARCARTTY TAYAARGARGARACNATHGAYYTNAGYAAYGTNTAYMGNTGGTGYAAYTGYYTNAGYACN MGNAAYCARGGNGAYCCNTCNYTNTCNGAYATGTCNMGNTCNGGNMGNCCNTGYGGNAGY GTNAAYGTNAAYAAYGCNGARAARGTNGAYGCNCCNGCNMGNTCNGAYMGNMGNACNTCN GTNGCNAARATHGCNTCNAAYYTNGAYGTNAGYGTNGGNAGYGCNGTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CCNMGNGARGARCCNMGNATHGGNCARAAYAGYAARTCNCCNMGN ACNCCNAARTCNCCNGCNGCNCARYTNGAYAAYGGNTCNGTNCAYCCNTCNGAYYTNCCN GGNCARTAYCARCCNCARAAYGARCCNCAYGTNTTYGARTCNAAYCCNGARCAYAAYCCN GAYGCNYTNMGNGARGCNGAYACNGAYAARAGYCARGGNYTNCCNAARAARAAYCARGCN AARAARATGYTNGCNMGNTTYCARAGYATHCARGCNGARGCNAAYAARGARYTNCCNAAR CCNGTNCCNAARAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GCNATGCARGAYGCNTAYATHCCNMGNGAYGGNGTNYTN GCNYTNGAYAARYTNTGGCCNGGNTGYGARGTNMGNTTYGTNGAYCARGGNCAYGTNGGN GCNGTNYTNYTNCAYCARAAYGTNTTYMGNAARGCNGTNGTNGAYGCNTTYGAYAARCAR ATHCARAARTAYAARGARGGNMGNYTNCCNACNGAYTTYMGNGAYTAYYTNAGYGAYTCN GARGTNCAYAARMGNGTNTTYTCNAARGARACNMGNGGNMGNYTNATHAGYMGNGTNGAR AAYGCNATH--------------------------------------------------- ---------ATGAAYMGNACNGGNAAYACNAARYTNGTNGCNTCNGTNGCNTCNCCNATG AGYCARACNAGYGTNTTYTGYAARTAYAGYCAYMGNGAYTGYACNCARAAYTGYYTNGAR GGNTAYGAYTAYTGYATHMGNCAYATHYTNGARGAYAARACNGCNCCNTAYMGNCARTGY GCNTAYATHACNAARGCNGGNMGNAARTGYCCNTCNGCNGCNCCNAARYTNGARAARAAR GARGGNTTYTGYGCNTTYCAYACNAARAARGCNYTNYTNGCNMGNCARMGNYTNTCNMGN AARMGNMGNYTNAARGARACNCCNGAYAGYATGYTNGARGAYYTNGTNGTNACNACNTCN GCNATGGARGCNAAYCAYAGYTCNGARCCNMGNMGNGGNAARGTNCAYAAYGAYAGYATH GCNTCNMGNGCNYTNGAYTAYGCNAGYTCNAGYGAYTCNGARGCNGARCCNCCNYTNGTN GARCAYGCNTGGMGNGAYTCNGGNGAYAGYGAYGCNGARAGYATHGAYAGYGAYCARGAR GAYGTNYTNAARTAYGCNGGNGTNTAYACNACNGARGARGTNGCNCARATHYTNMGNGAY AARYTNATHMGNYTNCARGCNYTNTAYATHGAYCARTTYAARMGNYTNAARCAYATHYTN TTYACNAARAARMGNAARTAYYTNGTNGCNCARAARAARGARAARGARYTNTTYGGNAGY ATHAARMGNTAYAARGAYGAYCCNCARCARMGNGARAARTAYAARAARYTNTGYGCNATG AARMGNTAYCAYAARAARTTYGGNYTNGAYGCNYTNATGCARCAYAARTCNACNCARMGN MGNYTNAARGTNACNGARGGNATGAGYCAYAARATHCCNACNCCNGTNCARTGYAGYTTY GTNGAYGARGGNYTNMGNTGYGCNCARACNGTNGTNCCNYTNAGYAARTAYTGYCARAAR CAYATHYTNCAYGAYCARAAYCARGTNYTNTAYMGNCCNTGYCCNTTYGCNGAYAGYCAR TGYGGNMGNCCNGTNCCNTCNYTNYTNGGNACNCCNTTYTGYTCNYTNCAYCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATHAGYCARTCNAAY GARYTNYTNAAYAARCARAARGCNGAYATHACNGGNATHCAYTCNAARYTNAARGARAAR CARAAYYTNGAYGAYGAYTTYAAYMGNGCNCARGARATGATHAARTCNYTNGAYAARGAY GTNTCNGARYTNAARATHAGYAAYMGNGAYYTNCARAARGAYATGGARTCNTGYMGNGAR MGNGARTCNAARATGYTNGCNYTNCARTCNGARYTNAGYMGNACNAAYGCNTGYYTNMGN TCNGARAAYACNACNYTNAGYAAYAARTCNACNAAYCARACNGCNGARGTNGARMGNYTN AARATGGARATHCARGARYTNGARACNACNGTNAARCAYYTNACNGAYTCNGTNGARGAY GARAARAARAAYAAYACNCARGCNATHGCNAARYTNAARGCNTCNYTNGARGARAAYACN AARGARAGYAGYGAYTTYAARCARAARTGGGARGAYGARATHGAYTCNAAYAARACNYTN AARMGNMGNCAYGCNAAYAAYGTNAARGAYYTNACNMGNCARYTNCARCARACNAARMGN MGNYTNGARGTNGTNGARGGNAGYMGNAARGAYAGYTCNGGNAGYATGGGNTCNMGNACN AAYTCNAAYGGNAGYYTNAAYTCNATGCAYCAYCAYAAYGCNCAYTCNGGNTCNTCNGGN ACNTCNGCNAAYTCNCARGARTTYCCNGTNATHACNGARCARGTNGARATHGAYAARCAR GTNYTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARTCNAAR AARGAYGGNGAYGARACNTAYCARACNTTYATHYTNCAYGAYGARGAYCAYACNYTNGGN AAYTCNYTNAARTAYATHYTNAAYAARAAYCCNGARGTNACNTTYGTNGGNTAYAGYATH ACNCAYCCNTCNGARAGYAARATHAAYYTNMGNATHCARACNACNGGNAARCCNGCNATG CARGTNYTNAARCARGGNYTNAARGAYYTNAARCARYTNTGYGGNCAYATHYTNACNACN TTYGARTCNTCNACNAARTAYTAYAARGARAAYCAYATGGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGNYTNGTNGARGGNTTYGGNCARAGYGTNAGYMGNTCNGGNGTNATG AARACNYTNGGNGGNGTNMGNAGYGTNGTNGGNACNCCNGARTGGACNAARTCNTCNGTN TGGATGCARGARAAYACNGTNTCNAARTGYMGNGTNTGYYTNGARGCNTTYGGNYTNATG AARGCNAARCARTTYTGYGTNGTNTGYGGNYTNGCNGTNTGYAARGCNTGYTCNGGNAAR GARYTNYTNYTNTAYYTNCCNGAYGTNGGNGGNGAYMGNAARATGGCNATHATHMGNATH GTNGGNTGYCCNGARMGNGARCCNGARATHAGYYTNCAYYTNMGNGTNTGYCCNATGTGY AARGARAARYTNATHTCNCARCARGTNGARGARGARGARGARGCNGARCAYGGNGTNMGN AARCARYTNCCNAAYTAYMGNAAYGTNGTNGARTCNYTNGARGAYGGNTCNMGNAARACN CCNGARMGNAGYAAYATGAARGTNYTNGCNAARGCNCARGARGAYYTNGCNGAYGCNYTN GCNGGNCAYGTNACNYTNGTNCARCARYTNAARAARYTNTCNCCNGGNACNAAYACN--- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AAYGCNTCNAARGGN AARCARACNGCNAARCAYGAYMGNMGNACNAARCAYCARTCNAARATGAGYTCNTCNGCN GCNGAYTCNGAYGCNYTNCAYAGYTGYGAYGARGAYGARGCNGTNGCNTGYGGNCARAGY GTNAARYTNTCNGTN---CCNYTNGCNATGTGGGAYTTYGARCAYTGYGAYCCNAARAAR TGYACNGGNAARAARYTNAGYMGNYTNGGNTTYGTNMGNACNYTNMGNYTNAAYCARMGN TTYAAYGGNYTNATHYTNTCNCCNGTNGGNACNAARTGYGTNGCNCCNGAYGAYMGNGAY ATHGTNGARYTNAAYGGNGTNGCNGTNATHGAYTGYAGYTGGGCNAARYTNCARGARACN CCNTTYGCNMGNATGAARGGNGAYCARYTNMGNYTNYTNCCNTAYYTNATHGCNGCNAAY CCNATHAAYTAYGGNAARCCNTGYAARYTNTCNTGYGTNGARGCNTTYGCNGCNACNYTN TAYATHACNGGNTTYGCNGARGARGCNGAYACNYTNYTNCARAARTTYAARTGGGGNMGN TCNTTYTCNACNYTNAAYAARGARYTNYTNGAYTCNTAYAGYAARTGYCAYACNAGYCAR GARGTNGTNTCNGARCARGAYAARATHYTNGCNGARYTNGARGARGAYGGNMGNCARAAY AARYTNAARGAYTGGATGGARATGGAYYTNAAYACNGAYGTNTGYAAYCCNAAYMGNCCN ---------ATHTCNGARTCNAGYTCNGARGARGARACNGGNGAYGARAGYGAYGARGAY GAYGAYGCNGAYGARGAYYTNGARCAYGARGAY---------------CARGARGARTTY MGNCARGCNGGNATGAARTGYGCNYTN------CARCAYCCNGARTTYATGYTNGARYTN ACNTCNCAYATGGGNAAYCCNGARGARATGGARCAYCCNTAYTTYYTNTGYAAYCAYCAR AARGTNYTNGTNAGYATHGTNGARTGYYTNAARGTNGARYTNATHAARTGYGTNCCNGAR GARTAYAGYGCNATGGTNATGGARYTNTTYCCNACNAARGARMGNYTNGCNGAYGGNTTY AARTAYATGTGYGAYCAYAARGARCAYTTYCARGAYAARTGYYTNCARGAYAGY------ ------GTNATGGAYATHTAYACNTGYTAYATGGGNAARGTNGCNCARYTNCARCCNCAR GCNGCNACNTCNCAYGAYATHAARGGNYTNTTYTGYAARGTNATHMGNTCNGARGARCAR TGYTTYMGNGAYAAYMGNGGNACNTGYAGYAARGARTAYATHGARTTYYTNGTNGGNATG ATHGARAARTTYTTYCCNACNACNGCNTGYAGYAGYTAYAARGCN---GTNACNCAYGAY AAYAAYGCNYTNGCNAAYACNATHYTNGGNAGYYTNYTN---GTNCAYGGNCARCCNCAR GGNCCNYTNAARTAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TCNYTNCARGTNTAYAARYTNCARCAR GAYCARAARGCNATGTCNGGNGARAARGAYAAYATHGTNGARGAYMGNGAYTCNYTNAAR ACNCARYTNGARCARGCNAAYTCNGARATHTCNAAYYTNMGNAAYCARYTNGARYTNAAR GCNAARATHMGNGARAGYYTNGCNYTNGCNGARTCNCCNGAYTCNAAYGARGARYTNGCN ATHAARAAYAARGARGTNATHAAYYTNCAYACNCARYTNCAYTCNTAYCARATHGAYGTN GAYAARAARAAYAARGARYTNGGNGARAARGCNAARGARYTNATHGGNTGYAARGARGAR GTNGARAARYTNAARYTNGARYTNGGNMGNYTNMGNAAYCCNCCNYTNGTNTGYGARGTN TCNAGYCARACNCAYGCNYTNAGYGARGTNTCNGCNYTNGARAAYGTNAARCCNTCNYTN ATGGGNGARMGNGARMGNACNATHCARACNYTNCARGARGARYTNAAYGARYTNMGNACN CARGTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYTCNYTNTGYCCNYTN YTNGCNGCNGTNYTNAAYYTNGTNTGYYTNGTNTAYATGYTNCARTGGYTNCCNACNGCN GARTCNTTYGTNCCNTAYTTYGTNATHATGGGNYTNTGGGGNGTNACNGAYGGNTTYTGG ACNGCNCARGTNACNAGYYTNATGGGNATHATHTTYCCNGAYAARATHGARGARGCNTAY GCNGGNYTNMGNATGACNCARGGNYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHGAYAGYACNCARYTNGTNGCNTTYAAYATGMGNYTNAARGARTCN CCNCARAAYACNATHGTNATHACNAAYGGNGGNMGNTAYGARGTNAAYGTNGGNACNMGN GTNMGNACNTCNGTNTTYTGGGAYCARGARCCNAARTCNGTNMGNMGNTGYTCNTGGTTY TTYAARMGNGARGGNGAYAAYMGNTAYATHCCNTAYGAYGARGARTTYTGYYTNAARYTN GARAAYGARTAYAARAARGCNYTNGARACNAAYGGNTGGCAYMGNMGNYTNGARTTYCCN GGNAARGARATHATHGTNATGCAYAGYGCNAGYGTNATHYTNCARTTYCCNTCNTCNTCN AAYYTNGAYGARTGGGGNAAYGTNYTNGGNGAYCARATGMGNCCNMGNGTNGTNAARMGN GGNGTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNCARGAYTAYAARCCNAARATHCARACNGARTAYYTNAGYGARGAYAGYAAR MGNAARATHGCNGTNAAY---------GARGARAAYGGNACNGARGARGAY--------- ---------------------ACNTCNGARCCNCCNAAYAARAARCARAARYTNAARGGN MGNAAYAARCARMGNCCNMGNAAYGARMGNATHGARCARAARGAYAARYTNTGYCCNTCN GTNAARAGYGGNAARACNTGYAAYTAYGGNGAYAGYTGYAARTTYAAYCAYGAYGTNAAY GAYTTYYTNGARAARAARMGNCCNGAYATHCARGARAARTGYCCNGTNTTYGCNMGNYTN GGNTTYTGYAARTTYGGNGTNACNTGYMGNTTYGCNAGYAGYCAYYTNGGNGAYAAYCAY GARAAYYTNGTNAAYAAYGAYYTNTAYGAYACNYTNAARGARAARCCNYTNTTYYTNAAY ACNYTNAGYGAYGAYGTNMGNMGNAARYTNTGGAARMGNAARTAYGAYTTYTCNAARGCN ATGAARTCNGTNAAYCAYGTNCARAARACNTTYMGN---AAYAARGGNGCNACNCARGTN TGYGAYAARCARAARGARGGNAGYAGYGCNGGNACNACNCAYGARAARMGNGAYGARTCN AARYTNGTNACNGARGCNGCNACNGTNAAYGAY------------GAYGTNAGYCCNACN GARCCNGCNCCNAGYAARAGYYTNGCNGARGAYGTNTCNGTNTCNGAYAARGTN------ ------------------------------ATHACNACNGAYAAYAAYGAYATHGARGCN MGN------------------------------------YTNACNCCNMGNGARGTNAAR AARATHGAYTTYCAYGAYAARYTNTAYYTNGCNCCNYTNACNACNGTNGGNAAYYTNCCN TTYMGNMGNGTNTGYAARGAYTAYGGNGTNGAYATHACNTGYAGYGARATGGCNYTNGCN TCNCARYTNYTNAARGCNAARGCNTCNGARTGGTCNYTNATHAARMGNCAYCCNTGYGAR GAYATHTTYGGNGTNCARGTNTGYGGNGCNTAYCCNGAYATGATGAGYAARTGYGCNCAR GTNYTNACNGARACNAGYGAYATHGAYTTYATHGAYATHAAYTGYGGNTGYCCNATHGAY YTNGTNTTYAARAARGGNAGYGGNAGYGCNYTNATGGGNAARGTNACNAARYTNGARCAR ATHTGYMGNAGYATGMGNGGNGTNATGGGNGARACNCCNYTNACNGTNAARYTNMGNACN GGNGTNTTYGAYAAYAARAGYACNGCNCAYACNATHATHCCNMGNYTNMGNGAYGCNGGN GTNTCNYTNGTNACNATHCAYGGNMGNTCNMGNGARCARMGNTAYACNAARYTNGCNGAY TGGGAYTAYATHGAYCAYTGYGCNAGYYTNGGNGGNTCNATGCCNGTNTTYGGNAAYGGN GAYATHYTNTCNTAYGARGAYGCNAAYYTNCARATGGCNMGNAGYGGNGTNTCNGGNGTN ATGATHGCNMGNGGNGCNYTNATHAARCCNTGGATHTTYACNGARATHAARGARCARMGN CAYTGGGAYATHTCNTCNTCNGARMGNTTYGAYATHYTNMGNTCNTAYACNAAYTAYGGN YTNGARCAYTGGGGNTCNGAYCAYCARGGNGTNGARACNACNMGNMGNTTYYTNYTNGAR TGGATHTCNTTYYTNCAYMGNTAYATHCCNGTNGGNGTNYTNGARCARGTNCCNCARMGN ATHAAYGARMGNCCNCCNTAYTAYATHGGNMGNAAYGAYYTNGARACNATGATGGCNAGY GCNAAYTGYGCNGAYTGGATHAARATHAGYGARATGYTNYTNGGNCCNGTNCCNTCNAGY TTYCARTTYYTNCCNAARCAYAARGCNAAYGCNTAYCAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARCCNGTNTCNGTNTAYTGYMGNATHMGNCCNYTNGAYGAYCCNAAYGARCCNACN TGYATHAARCCNYTNAAYGARGCNGTNGTNCARGTNCARACNCCNGARAAYGCNCCNACN MGNAAYGGNCARTTYAARGARTAYCARTAYACNTTYCARCAYGTNTTYGAYGAYTTYACN TCNCARAARACNGTNTTYGAYAARGCNGCNYTNCCNATHGTNGARGAYYTNYTNTCNGGN AARAAYGGNYTNYTNTTYACNTAYGGNATHACNGGNTCNGGNAARACNTAYACNATGACN GGNGTNCCNCARGAYCARGGNATHYTNCCNMGNTGYYTNGAYGTNYTNTTYAAYAGYATH GGNGAYMGNCARGCNAARAARTAYGTNTTYMGNCCNGAYCAYATGAAYGCNTTYGAYGTN CARAGYGARGCNGAYGCNATGATGGARMGNCARAARAARGAYATHYTNCCNGGNYTNACN TCNGGNAGYAARACNTCNYTNAARMGNGGNGAYAAYGAYGAYACNGARMGNATHATHGAY CCNACNACNGTNGARGGNGTNGARGAYGAYAAYAAYTAYTCNGTNTTYGTNTCNTAYATH GARATHTAYAAYAAYTAYGTNTAYGAYYTNYTNGARGAYYTNCCNTAYAAYACNATHACN GGNTAYAARCCNCCNCARTCNAARATHYTNMGNTCNGAYCCNTCNGARAAYATGTAYGTN CAYAAYTGYACNGARGTNGARGTNAARCARCCNCARGAYGCNATHGAYGTNTTYTAYAAR GGNCARMGNMGNMGNAARGTNGCNCAYACNACNYTNAAYGCNGARTCNAGYMGNAGYCAY AGYGTNTTYAAYATHMGNYTNGTNCARGCNCCNYTNGAYAAYMGNGGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GTNCARYTNMGNGARCARGCNYTNAARGGNGCNGARGARGARATHATGAAR YTNAARTCNAGYAARGARGCNAARGTNGAYAARACNYTNATGCAYAAYATGGTNYTNACN TGGYTNACNTCNCCNGARAARAARMGNCAYGARATHGTNCARYTNATHGGNCAYGTNYTN GAYTTYAGYTCNGAYGAYTTYTCNAARATHGCNTCNGCNCAYAGYCARGAYAAYYTNTGG ATHGGNTTYTTYAARMGNTCNGCNTCNAARTCNACNCCNACNACNCCNAGYAARGTNGAY CARTCNTTYTCNCARYTNTTYGTNAARTTYYTNGARAARGARTCNYTNCCNACNCCNTCN CCNGTNGARYTNCCNGTNGARGCNATGGCNGCNGARGCNCARCARMGNCAYAARGCNGCN TTYAAYCCNTTYATGGCNCCNMGNCAYGTNACNCAY---GGNAAYGARGCNCCNGGNTCN TCNGGNTCNTCNTCNCAYYTNYTNATHCCNCAYGAYAAYCCNCAYCCNTCNCCNYTNTTY GCNCCNGTNACNAGYGTNTCNAGYGCNGGNGARAGYGCNATHYTNAARGAYGTNYTNTGY TAYGTNTAYYTNGCNAARATHMGNTCNTGYACNGARCARTCNGGNAAYATGYTNTGYCAY TCNCAYGCNTCNMGNTAYTTYTGYTGYAAYGGNTAYMGNTGYAAYGARAAYYTNACNACN CCNTCNCCNCCNYTNACNTCNGCNGARGARAARGARTCNACNAAYMGNATGGTNYTNACN GTNTCNGCNGTNGCNGGNGTNGTNATGYTNYTNYTNGTNYTNACNYTNGGNGCNGTNTGY TTYGTNCAYMGNGTNMGNMGNAAYAARGAYMGNMGNYTNAGYTCNYTNATGGARAAYMGN YTNYTNGAYGARGARGGNTCNGGNTCNAARGTNTTYGGNGAYCAR---TCNTCNGGNAGY GGNTCNGGNCARGCNAARYTNGTNACNMGNACNGTNGGNAARGARGTNCAYYTNATHGAR AARATHGGNAAYGGNMGNTTYGGNGARGTNTGGMGNGGNAARTGGYTNGGNGAYGAYGTN GCNGTNAARATHTTYACNTCNYTNGARGARTCNAGYTGGMGNCARGARATGGARATHTAY AAYACNGGNATGYTNAGYCAYGARAAYATHYTNGTNTTYCAYGCNTCNGAYACNATHGGN MGNTTYTCNTGYACNCARAAYYTNYTNATHGTNCARTAYCAYCCNAAYGGNTCNYTNTAY GAYTAYYTNCAYMGNAGYGAYATHGAYATGGARGARATGYTNATGYTNGCNAGYTCNGCN GCNGCNGGNATHAGYCAYYTNCAYTAYGARATHAARCARGGNACNGGNACNCAYGARAAR CCNTCNATHGCNCAYMGNGAYATHAARTCNAARAAYATHYTNGTNAARYTNAGYGGNGAR TGYTGYATHGGNGAYYTNGGNCAYGCNATHAARAAYACNAARGARTGGGAYMGNGGNMGN GARMGNCCNTGGGTNGGNACNAARMGNTAYATGGCNCCNGARYTNYTNTCNAARACNYTN AAYCAYGCNCAYTTYGARTCNTTYMGNTGYGCNGAYGTNTAYGCNTTYGGNYTNGTNYTN TGGGARATHGCNMGNMGNGCNMGNCCNTAYTGYGAYGAYTAYMGNGTNCCNTTYTGGGAY YTNGTNCCNCCNGAYCCNAGYYTNGARGARATGAARGARGTNGTNGTNGAYMGNGGNYTN MGNCCNGCNATHCCNAAYAAYTGGTCNCARGARCARYTNATGYTNGARATGGARAARYTN ATHGCNGGNTGYTGGGCNCARCAYCCNTCNAAYMGNYTNAAYATHYTNMGNGTNAARAAR AAYYTN---CARGCNYTNMGNTCNCAYAAYGARCARATGATGGARAARMGNGARAARYTN ACNGGNAARATHYTNGAYGGNAGYACNACNACNAAYAGYGTNGTNACNACNTCNAGYAAY ATGYTNTTYAAYYTNGAYGAYTGGAARCARGGNATGGAYYTNYTNTGYGAYGAYYTNAAY MGNAARYTNGTNTTYMGNGARCAYTTYGAYTGYYTNTCNAARTTYGCNCCNMGNATHTCN GGNTGYATHATGACNAARACNCAYYTNTTYMGNACNGCNATHYTNGAYGCNGGNATGGCN ACNCAYMGNACNYTNCAYGAYATHACNTGYAAYTTYGCNGARAAYATHGTNAAYTGYYTN GARMGNCCNYTNAGYAARAARTGYCCNGTNMGNGTNGTNGAYACNATGGTNACNGCNYTN CAYMGNTTYYTNCCNCCNGCNTGYGCNCCNYTNCCNGCN------------ACNGAYGTN AAY---------------------GARGCNACNGTNATGGARGCNGTNATHYTNGARGGN GGNGGNGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CARCARCAYAAYTTYATG CARGCNTCNAGYAGYGCNCCNGAYCCNGAYATGTCNAGYCCNYTNGTNGAYGGNTCNYTN GGNGGNGCNGARTTYATHCCNACNAAYTAYGAYYTNYTNGGNGAYTTYTGYTCNGTNGAR CARYTNGARYTNAAYGGNTTYYTNAAYGAYAGYGAYYTNATHGARYTNCARCCNTCNYTN GGNACNGARGGNYTNAAYCARTCNGGNYTNGTNTCNGGNTAYGAYGGNYTNGARCCNGAY GGNACNYTNTCNATGTCNCAR---------ACNGCNACNGTNGGNGTNAGYCARTCNTCN GAYYTNTCNCAY---------ATHTCNGTNCARGAYGARATGTGGMGNAARGARMGNATH AARAARGAYAAYCAYAAYATGATHGARMGNMGNMGNMGNTTYAAYATHAAYGAYMGNATH AARGARYTNGGNGGNYTNYTNCCNAARACNATGGAYCCNGAYAAYMGNCARAAYAARGGN ACNATHYTNAARGCNTCNGTNGAYTAYATHAARGCNYTNCARTCNGARCARAAYMGNTTY MGNGTNATGYTNGAYGARAARAARAARGCNGARYTNGAYYTNMGNAARGTNYTNATHMGN YTNAAYCARATGAAYYTNGTNATGAARTCNCAYGGNATHGARTCNGGNACNYTNGAYGAY YTNGARYTN---GCNTCNAGYGTNGCNACNAGYCCNATGACNYTNACNCCNTCNTCNCAY AGYGCNCCNGTNGTNACNATHATGTCNAAYAGYAGYCARGTNTTYYTNACNAGYACNYTN ATGTCNCCNGTNGAYGAYYTNATGGAYGAY------TCNCCNGTNAGYGGNGAYCCNATG YTNATGTCNGCNCCNGTNAGYCCNGAYGCNGAYGARGTNGGNTTYCAYTTY--------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNCARGAYGCNYTNAAYGCN TAYGGNCCNAAYTCNCARCAYTTYYTNAARGAYTCNGTNGTNACNCCNTGGGARMGNGCN GTNGCNGTNAAYAARGTNCCNTAYTAYATHAAYCAYGAYACNGARACNACNCARTGGGAY CAYCCNCARYTNACNGTNATHATGGAYCARYTNATHGAYATGAAYAARATHMGNTTYGCN GCNTAYMGNACNGGNATGAARYTNMGNTGGYTNCARAARGARYTNCAYYTNCAYACNGTN ACNYTNCARATGGCNATGGAYTCNTTYGAYAGYCAYGGNYTNMGNGGNMGNAAYGAYAAR YTNATGGAYGTNGGNGARATHATHGARTGYYTNTCNTCNATGATGGARGCNGCNGCNGGN CARCAYCCNGAYGTNGTNAAYGTNCCNATGTGYGTNGAYYTNACNYTNAAYTGGATHYTN GAYGTNTAYGAYAGYGTNMGNAGYGGNAARATHMGNGTNYTNTCNTTYAARGTNGCNGTN GTNYTNYTNTGYCARGCNCARYTNGARGAYAARTAYMGNTAYATHTTYMGNYTNATHGCN GAYGCNAAYGCNTTYGCNGAYCARMGNAARATGGGNYTNYTNYTNCAYGAYTGYATGCAR ATHCCNMGNCARYTNGGNGARATHGCNTCNTTYGGNGGNAGYAAYATHGARCCNAGYGTN MGNAGYTGYTTYGARAARGCNAAYGGNMGNCCNGARATHGARGCNTAYCAYTTYYTNGAY TGGYTNAARYTNGARCCNCARTCNATGGTNTGGYTNCCNGTNYTNCAYMGNGTNGCNGCN TCNGARACNTCNAARCAYCARGCNAARTGYAAYGTNTGYAARGAYTTYCCNATHYTNGGN TTYMGNTAYMGNTGYYTNAARTGYTTYAAYTTYGAYGTNTGYCARAAYTGYTTYTTYTCN GGNMGNAARGCNAARAGYCAYAARYTNACNCAYCCNATGCARGARTAYTGYACNACNACN ACNTCNGGNGARGAYGTNMGNGAYTTYTCNAARGTNTTYAARAAYAARTTYAARTCNAAR MGNCAYTTYAARAARCAYCCNMGNMGNGGNTAYYTNCCNGTNGAYTCNCAYYTNGARGGN GAYAGYYTNGARAGYCCNAAYCCNTCNCCNCARCAYAGYATHTCNCARGAYATGCAYTCN MGNYTNGARATGYTNACNAGYMGNATHGCNGARGTNGARCARMGNCARGGNGGNCCNACN GAYYTN------------------------------------------GARGAYGARCAY CAYYTNATHGCNCARTAYTGYTCNAGYYTNAAYGGNGARCCNAAYTCNCAYGCNYTNAAR AGYCCNATGCARATHATGATGGCNGTNGAYGCNGAYCARMGNTCNGARYTNGARTCNATG ATHCARGAYYTNGARGAYGARAAYAARACNYTNCARGCNGARTAYGAYMGNYTNCARATG GCNGCNCAYGARMGNGCNTCNGAYCCNTTYMGNYTNTCNGGNTCNGGNGAYAGYAAYGGN GGNCARGGNCAYGTNAGYMGNGAYGAYGARATGATHGARGARGCNAARYTNYTNMGNCAY CAYAARGGNMGNYTNGARGCNMGNATGMGNGTNYTNGARGAYCAYAAYTCNCARYTNGAR TCNCARYTNACNAARYTNMGNCARYTNYTNGARCARGCNCCNGGNGAYACNCCNCAYATH TCNYTNGAYTCNTCN---MGNACNACNCCNYTNACNACNCCNTCNTCNTCNCARAGYTCN TTYCAYATGGGNACNYTNAAYTAYMGNATGGCNCCNCARATGGARTCNTCNCCNCARYTN AAYGGNCAYAGYGCNATGAGYYTNACNGAYGAYCCNGAYYTNAGYGGNATHATHGARAAR GTNGGNAGYCCNCCNCCNCARTAYAAYGCNATHAARAGYAARCCNAAYGTNGGNGAYYTN TTYCAYATHGCNGGNGARYTNGGNGARGCNGTNGGNTCNYTNGTNACNGTN--------- ------AARMGNACNAARAARACNAARAARAARAARGARYTNAARAGYAAYACNAAYAAR GARGARAAYAAYGAYTCNGARTCNGARAARGARAARAARACNAARAARAARGCNAARGAR TCNAARGAYAGYTCNGAYAARGARGARGAYGARAAYGAY---AARACNAARAARGGNAAR AARAARGGNAARGARGCNTCNTCNTTYGGNGTNGTNGAYACNAARYTNYTNAARGAYCAY GGNGARGAYGCNGARACNAGYGAYACNAARAARAARGGNAARMGNAAR------------ ------------------------------------------CCNAAYCARGTNAAYMGN GCNYTNAAYTAYYTNMGNYTNTGGAARAAYAAYTTYMGNTCNTGGAARTTYAGYAARYTN TAYCARGCNMGNYTNATHAARATHATGTAYGAYGAYTCNGCNGTNACNGARGARGAYTTY GARATHTGYYTNCARTAYTTYGARAARAGYYTNGGNAARGTNMGNGARCARYTNAARTCN GAYGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TAYYTNCCNTGYGAYGAYTTYATGAARTTYCARGAYGCNYTN AARAARYTNMGNATHATHGAYGAYMGNATHATHCAYGCNYTNAAYAARAAYATHCCNACN CARTCNTTYCARCARCARGTNGAYGTNGCNTCNAAYTGYMGNCAYATHTAYGAYGAYATH CARACNTCNTAYAGYCARMGNGARAARTCNATHCARCARTGYATHMGNATHGTNAGYAGY GAYGTNAARAARYTNAAYGAYAARMGNCARCARGAYCCNGAYAAYYTNGAYGTNATHMGN CAYYTNMGNAAYGARCARACNAARYTNMGNYTNATGCARCARGARATGAAYGTNGARGAR GTNGTNAARGAYMGNACNYTNAARGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GCNGTNYTNGCNYTNYTNGTNTGY TCNATGGCNAARCCNGTNYTNAARGAYCCNCAYCCNGGNGAYCCNGTNGARGGNAAYTCN CCNGAYGARAARCARGAYGARCCNYTNGGNYTNGCNTAYGARCAYTAYYTNAARGARGTN GTNGAYGTNYTNGARAGYGAYGCNGCNTTYAARAARAARYTNGARACNGCNAAYGTNACN GAYATHAARAGYGGNAARATHGCNATGTAYYTNGARYTNGTNAAYCAYACNGTNMGNGAY ATGYTNCAYGARYTNAARMGNAARGARYTNTCNMGNYTNTCNCARYTNGCNMGNYTNCAR ATGAARGCNAARACNGGNATGAARCAYTTYGARATHCCNGAYCAYYTNGAYYTNGGNAAY CARMGNACNTTYGARATHAARGAYYTNGARAAYYTNATHAARAARACNACNTCNGAYYTN GARAARYTNGAYGARCARMGNMGNAARGARTTYAARGARTAYGARATGGARAARAARTTY GARGARGARGARCAYYTNAARGARYTNAGYGARGAYGAYMGNAARAARGARACNGARCAY YTNGARGARGCNAARAARAARCAYAARGARCAYCCNAARYTNCAYCAYCCNGGNAGYAAR GAYCARTTYGARGARGTNTGGGAYAARGAYGAYCAYYTNGARGARATGGAYTTYGAYCCN AARACNTTYTTYATGACNCAYGAYATHAAYGGNGAYTTYGARTGGAGYATHGAYGARGTN GAYGCNGTNYTNCARMGNGARYTNGAYAARGTNTAYGAYCCNAAYGGNGAYCCNAARGAR GAYGAYCCNATGGARMGNGARGARGARATGAAYMGNATGMGNGARCAYATHTTYACNGAR ATGGAYAARGAYAARAAYYTNMGNATHTCNATGTCNGARTTYYTNATHTAYACNGGNCCN MGNGGNGARAAYAARGAYTTYCARAARGAYGARGGNTGGAARACNYTNGAYGARGARCCN GTNTTYGAYGARGAYGARTAYATGGARTAYGTNMGNCARTTYCAYCCNCARCCNGGNGTN GTNGAYCCNCCNGAYCCNAAYYTNCAYTTYAAYTCNGARAAYCAY---CARCARCARCAR TTYGAYCAR---------CAYCARCARCAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GCNTCNTCNAARAARATGGCNAARCARGAYGCNGCNAARGARACNYTNAARATHYTN ATHCCNAGYYTNTGYAAYAARATHTCNGAYCARGARYTNAARAAYACNGTNACNGAYYTN TCNTTYTTYGAYGAYATHCARGTNGARGAYCCNMGNATHYTNGAYYTNGGNAAYAARGTN GGNCARCCNACNCCNTTYCARYTNYTNMGNGARTGYYTNMGNMGNAAYTTYGGNTGGGGN GCNACNGARTGYGCNGTNAARACNACNGCNYTNAARAAYCARAARTGYGARTTYACNYTN ACNGTNGGNAARCAYGARGCNACNGTNGTNGCNAARAAYAARMGNGAYGGNAARCARCAR GCNGCNCARTGYATHYTNGCNAARYTNCAYCCNCAYGTNCCNAGYTGGGGNTCNYTNYTN MGNYTNTAYGCNACNAAYGTNGARAARCCNATGGARAARGTNGARGARATGAAYGARATH AARACNCAYGTNCCNAAYAARGCNGTNYTNGARAAYYTNMGNGARGARATGMGNAARYTN CAYAARCARAARGARTCNATHCCNGTNAARGGNAARATGATHATHTCNACNAARGAYYTN CCNAGYAARATGTCNTGYGTNGAYYTNATGGTNGCNTTYGGNYTNCAYYTNGGNGCNTGY TCNGCNTGYYTNGCNGTNCAYMGNGAYGGNAARACNGARGTNATHGCNAAYGAYYTNGGN GAYMGNGTNACNCCNACNGTNGTNGCNTTYACNGAYCAYGARATHGCNGTNGGNYTNAGY GCNAARCARGGNGCNGTNMGNAAYGCNGCNAAYACNATHGCNCAYGTNAARCAYATHGTN GGNTGYGAYAGYGAYGAYGTNYTNGTNAARGARTAYATHCARAAYCAYCARGTNGARGTN GGNGAYCARAARGGNGARGTNATHTTYAAYGTNGARTAYCARGGNAARAARGCNCARTAY ACNACNAGYAARATHYTNGARYTNATHTAYACNAARATGYTNGARACNGCNCARAGYCAY GGNGGNAGYGGNACNMGNGAYGCNGTNYTNGCNGTNCCNTCNAAYTTYACNCARGARCAR MGNAAYGTNYTNAGYGARGCNGCNACNAARGCNGGNTTYAARGTNYTNMGNATGATHAAY GARCCNTCNTCNGCNATGYTNGCNTTYGAYGTNGGNCARTTYGAYGARTCNGARCARGAR TTYAARACNYTNGTNTAYMGNTTYGGNGGNACNTCNCAYGAYGCNACNYTNGTNAGYGTN CARCAYGGNATGTAYTAYATHYTNGCNAARGCNTCNGAYAGYCARTTYGGNAGYGAYAAR YTNTCNGARGTNYTNCARGGNTTYYTNGCNAARGARTGYAGYMGNCARYTNCAYTGYGAY ATHACNGARAGYAARMGNTCNATGGGNAARYTNAARYTNGCNGCNGARMGNTGYAARCAY CARYTNAGYTCNGTNCCNAAYGCNCARTGYAGYGTNGARTCNYTNTTYGAYGGNYTNGAY TTYTCNTAYAAYGTNTCNMGNGCNMGNTTYGARYTNYTNTGYACNCCNYTNATGTCNCAR TGYACNCARYTNGTNCARCARGTNYTNGAYATHGCNGGNTGYACNAARGARGAYGTNTCN AARGTNATHYTNTGYGGNGGNGGNGCNAARTTYCCNYTNGTNAARAARGTNATGGGNGAY TTYYTNCCNTCNTCNTCNYTNYTNAAYTCNATGATHGARGAYGARATHATHGCNGTNGGN GCNGCNAARGARGCNGCNATGYTNGARGTNGAYGAYGAYGARGARGTNAARGTNCARGAR GARGGNTCNAAYGCNTTYAARTCNYTNTCNAARGCNATHTGYGTNMGNGTNAAYTCNGAR GARYTNAAYGTNATHYTNCCNCARCAYTGYYTNATHCCNACNMGNMGNCARCAYACNYTN ACNYTNCCNGCNACNCARTCNTGYGTNAARYTNGARATHYTNCARGCNCARGARCCNATH ACNTCNGAYACNGARGCNCARYTNYTNGCNAARATHGTNYTNMGNGAYYTNCCNCCNGGN TCNAGYATHAARACNAGYTTYCAYYTNACNMGNCCNACNCCNCCNGCNTTYCCNAAYGCN TTYAGYATHTCNTTYAAYGAR------------------ATHGARAARYTNTTYGTNAAR GTNYTNAGYATGAAYAAYGGNTCNTGGCAYTTYGAYTTYGCNAAYMGNMGNGCNMGNTTY GAYCAYAAYMGNGGNCARACNAAYAAYTTYTGYGAYAAYCARAAYYTNAGYCAYAARGAY CCNAARGCNGGNTGYCARYTNTTYTTYACNCCNGARGAYGAYATGATHGTNTAYTAYCCN GGNGCNCARAGYTGYTGYMGNYTNTGYGGNAARCAYGARGGNTGYACNATHYTNAARCCN AAYTGGYTN---CARGARTCNAARYTNATHTCNATHGARGARATHAAYGGNATGAARTGY TAYGGNTGGGCNAARAARGGNGCNGTNGCNGCNGCNGAYACNTGGTTYGCNACNGCNGAY GGNGTNCCNTGYMGNTAYCAYGARGTNGTNCAYCARATHGAYCAYAAYYTNACNTTYATH CCNCARACNTAYAARATHGGNCCNCARGAYCCNTCNYTNTTYCAYGTNCCNTCNTAYTGY AAYAARACNTGYCCNCAYCCNTAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHMGN CCNCCNATGAARGAYTCNACNACNTGGACNGGNCARGCNGAYTAYGAYMGNTTYYTNTTY ATHMGNATHTTYTGYCCNGARGGNYTNGARCARYTNGGNACNGGNATHAARTGYTCNYTN TCNTAYGAYGGNAAYATGTTYAARACNCCNGTNYTNGAYTCNCCNGAYGAYGAR------ YTNTCNGARGARACNGAYGTNGTNGARGARMGNACNAGYCARMGNCCNCARGCNGCNMGN AARTCNGAYGARMGNTCNAAYAAYGAYGTNACNCARGARACNGAYTCNGCNAARTCNAAR TCNAARAARTAYTAYGARTTYGARATHCCNYTNCCNGAYGARATHACNGARGGNATHYTN YTNYTNGGNGARAARCCNGGNCCNGARCCNGARAAYATHMGNATHGCNATHCAYCAYGGN CARTTYGARGARATHATHGCNATGGCNACNATHGAYTTYCARGAYATHAARGARYTNACN YTNGARACNATHTGGYTNCCNGCNCCNACNGGNGAYGAYGAYGTNGCNGCNATHAARTCN MGNTCNAAYTCNYTNAGYGGNGCNTCNAGYYTNGGNGGNGARTCNYTNAAYGAYTCNATG GAYATHCCNATHATGATGGAYGAYAAYCARTCNGAY---GGNGGNGGNYTNGTNTCNTCN ACNCCNMGNGAYGAYATGTTYAARGCNAARGAYCCNYTNCCNTTYCCNYTNTAYCCNYTN CAYGGNGGNAARACNGAYTCNYTNCAYGTNCCNTGYGGNAAYGTNCCNYTNTTYATGTAY TGGGGNAARMGNCCNMGNCCNYTNAAYTTYAAYMGNCARTGYGGNACNYTNGGNATHTAY GAYATHGTNTAYGAYATHACNGGNTAYGAYATGACNACNACNACNAARGARGAYYTNCAY AARGARATGGTNGAYGARGCNYTNTCNGTNGCNGCNTTYACNCCNGAYCCNGARACNGAR GAYAARTCNACNAGYGTNGARGARACNGTNTCNAARTCNGARTAYGAYMGNYTNGTNGAR AARCAYCARGARGARATGATHTAYYTNCARGARGARTAYGARAARMGNYTNCARGARYTN GTNCARAAYYTNCARACNATGCAR------------------GCNGARAAYGARCAYGTN CCNCARCCNCARCCNMGNCCNYTNTCNCARGCNTCNMGNGTNAGYACNACNCCNGGNGCN ATGACNCCNATHACNTCNAARMGNTCNGARMGNTCNGAYCCNTCNTTYTAYGARAGYATG ACNYTNCCNCARACNGGNCARAGYATGMGNACNTTYAGYMGNGAYAARACNAGYGTNGGN GARATGGAYMGNGARAARAGYCAYYTNTCNCARAGYACNGGNAGYACNMGNYTNAARCCN YTNCCNCCNMGNAAYATGAARCCNAGYAARAAYTTYMGNATHGGNAARCCNYTNCCNAAR TGGGGNGARACNYTNCCNCARGAYTTYTTYGAYMGNYTNMGNYTNTGGGARGARGARMGN AARCARCAYAARCARGARYTNAAYGARAARACNYTNAARGAYATHAARGAYAAYYTNGAR AARAARYTNGCNGGNCARCAYAARYTNAGYAARMGNGARGARCARATHTAYGAYGCNYTN AARGAYGTNAGYYTNCCNGCNYTNTCNATGCCNTAYAARTCNGGNAAYATHTAYAAYCCN MGNGCNCAYCAYTAYTTYCAYCCNACNGGNTCNTCNGARGTNMGNYTNACNCARCCNCCN TCNATGTTYACNYTNCCNCCNYTNCCNAAYAGYAARYTNTCNATHGTNAAYYTNTTYGAR YTNAGYAARAAYTTYTGYAAYMGNGGNCCNGCNTGGYTNGTNGARMGNTAYATHCARCAR CARCARCCNTCNCAYGARGAYTGYCCNCARACNCCNGCNCCNACNTCNGCNGTNCCNCAR GTNACNACNACNTCNGGNCAYACNCCNATHAAYGARCARGTNGCNACNCCNACNAGYCAR MGNAGYYTNCARCCNGARYTNGAR------------------------------------ ------------------------------------------------------------ ------------------------------------GGNCCNACNTCNTGYACNATHMGN ATHACNTCNCARTCNACNTTYCCNGGNATHTAYYTNMGNYTNACNATHGTNGCNATGGAY ATHCARGAYTGYMGNACNCARYTNACNATHTTYGAYGGNGARACNACNCARATHYTNGGN TCNTAYGAYTGYMGNAGYAGYAARAAYGARAAYYTNAAYCCNATHCCNACNAGYGGNGAY ACNGTNACNTTYATHATGACNMGNGCNAAYCCNGAYAAYCAYCARTTYGAYATHGARGTN MGNGTNCARCCNATHMGNAGYGGNGTNGAYCCNGAYAAYGAYTAYAAYTAY--------- TTYAGYTTYCARAARTTYGAYCARGARGCNATHGTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR GARAAYMGNTTYAARMGNACNGCNGAYGCNYTNCARAARTCNGGNYTNTGGGAYATHGCN ATGAARACNGGNCAYYTNATHAARMGNAAYCARGARYTNCARAARGAYYTNGAYGARTTY AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ACNACNATHGTNCCNATHAARGTNCCNYTNMGNGARGGN YTNACNAGYTCNYTNCCNTAYGARGARMGNTTYCCNCCNTCNGCNYTNYTNGARYTNGTN GARGARAAYGAYYTNAARYTNGGNGGNGTNGTNGAYYTNACNTTYACNACNAARTAYTAY GAYCCNCARTTYTTYACNAGYCAYGAYATHGGNTAYCARAARGTNTTYACNGCNGGNCAY GTNATHCCNAAYGAYAARACNTTYATGCARTTYGCNAGYGCNATHAARACNYTNGARAAR GARGGNAARGTNATHTGYGTNCAYTGYACNCAYGGNYTNAAYMGNTCNGGNTAYATGATH TGYMGNTAYATGATHGARGTNYTNAAYATHGARCCNCARACNGCNATHMGNYTNTTYGAR CARGCNMGNGGNCAYAARATGGARMGNCARAAYTAYATHGAYGAYYTNATGMGNMGNACN CCNGGN------------------------------------------------------ ---------------------GTNGTNTGYYTNGCNAAYAGYCCNCCNTCNYTNTCNGGN AARGTNGTNTCNMGNGTNATHGCNAARGTNGGNAARAAYACNAARYTNYTNTGYCCNGCN AAYTCNGAYCCNACNYTNACNCARTGGAARAARAAYGGNCARGCNYTNAAYCCNGGNTGG GARMGNTTYAARGTNTCNMGNGARGGNCAYYTNMGNATHMGNAAYGTNCAYYTNGCNGAY GCNGGNYTNTAYACNTGYGTNGCNACNAAYGGNTTYGGNAGYATGAAYATHAAYTAYACN GTNATHGTNYTNGAYGARGARAAYAAYGTNTTYCARGARGCNGAYAARYTNATHAARCAR TCNCCNAAYGARGAYATHTAYMGNGARGGNTCNGCNCCNGTNTTYGARGARATGTCNAAR ATGMGNGARATGATGACNYTNAARMGNCCNMGNGGNTCNACNYTNMGNYTNATHTGYAAR GCNGGNGGNAAYCCNCARCCNCARATHCARTGGTAYAARGGNTCNGARYTNTAYAAYCAR MGNMGNGCNCAYGCNACNYTNAARATHTAYCARGTNACNGGNAARGAYAGYGGNMGNTAY ACNTGYGTNGCNAGYAAYMGNYTNGGNCARACNAAYTTYACNTAYAAYGTNCARATHATH GAYGARATHACNCARGCNMGNYTNATHGCNCCNCAYCCNATGAAYAARACNGTNCAYGTN GGNGAYTCNGTNTCNTTYCARTGYTTYATHGARAGYGTNGTNMGNCCNAAYGTNCARTGG YTNAARMGNGTNGAYGCNACNGAYAARATHTCNGAYCCNAAYATHAARYTNTTYCAYTAY AAYAARCARACNTTYATGGTNYTNAAYAAYGCNGGNATHCARCARGCNAARCCNGAYGGN TCNTAYYTNAAYAARYTNAAYATHAARTCNGTNACNYTNCARGAYGCNGGNATGTTYGTN TGYATHGCNACNAAYMGNAARGGNTTYGTNMGNMGNCAYGCNTTYYTNCAYGTNGTNGAR GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGNGGNMGN GCNAGYCCNGTNTCNGAR---AGYMGNAGYTCNAGYGGNAGYCCNACNCCNAGYGAYAGY AGYAGYCARAAYGCNGCNATHAGYCARCARGCNYTNATHGCNGCNATGCCNATGAARAAY GARGARACNTCNAARYTNACNGCNTCNYTNTCNAAYTAYTAYAAYGARTCNYTNATHGGN CAYGTNYTNGGNTGGCARGCNGAYGCNTTYGARAARCARGCNTCNAARYTNTGGGARGAR ACNATHGTNAAYGGNAGYYTNCARTGYAGYCARATHTCNGTNCARYTNAARAARGCNMGN TCNYTNGTNMGNATHGCNGARATHCARTCNACNYTNCAYGARCARMGNATHATGTCNTCN GAYCARCARMGN---AARACNTTYATHGCNGAYACNAARCARTAYTAYMGNATHACNTCN GGNYTNTGGAGYGGNGARAGYATGAGYMGNTTYACNMGNMGNGARYTNGARYTNTAYAAR CARTTYTCNTCNGAYYTNCCNGTNATGGGNATGGTNYTNATHATHGCNTTYGCNCCNGGN GGNGTNTTYATHTTYCCNYTNGCNTAYATGTTYCCNMGNTAYYTNYTNTCNCAYCAYTTY TGGACNMGNGARCARAARGARGARTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARTGYTCNTAYCAYGTNMGNAAYGAYATHMGN GTNGAYGTNGARAAYCAYATHAARGAYAARATGGARAARMGNGGNAGYTGGGAYGARGTN GCNGTNTGYYTNGARAAYAAYTAYGGNGAYAAYGARMGNACNACNTAYGTNAGYGAYATH TGYGGNATHGTNGARMGNAAYGAYGGNATHGTNTGYMGNTAYGGNATHGGNAARCARGTN GARMGNTTYATHAAYGARCARATHGARCAYYTNCARTGYACNTGYAARGCNYTNCARACN TCNAAYACNGARGAYCAYGAYCAYGGNYTNTCNACNGCNGTNATGGGNATHGGNGCNGGN GCNYTNGTNYTNYTNTTYATHYTNTTYYTNGTNTTYTAYTGYTGGMGNMGNAARMGNMGN AAYMGNAARAARAARAAR---GTNCCNAAYGTNATHTAYYTNCCNGCNGCNAAYTCNGAR AAYTAYCCNGTNTAYCARGARATHTTYGAYCARMGNTCNCCNCCNTCN---------AAY CCNCCNACNYTNCCNAGYMGNTAY------------GGNTCNMGNCCNYTNCCNGGNCAY CCNATHGAYGAYGTNGARTAYYTNGARCCNGTNCARGCNCARGCNGCNGGNAGYTAYMGN AARGCNCCNACNCARYTNMGNGGNGTNGTNAAYAAYCCNGGNTAYAAYGTNGAYGCN--- ---CCNCCNGARTAYAGYGARACNGAYCARATGTAYGARGAYGCNGTNYTNATGACNCCN GARGARGTNAAYGTNTAYATHGAYCCNATHGTNACNCCNAARGARAAYAARAGYGGNGGN TAYGAYTCNYTNGAYATHMGNGAYGAYGAYAAYCARGCNGARTAYCARCCNYTNGARGAY GTNGAYMGNAAYAARAARYTNGGNCCNGAYCCNGCNGAYMGNACNAARAARGAYGAYMGN GARACNGARTCNGARTAYTTYGARYTNGARATGYTNGARGARGGNAGYTTYACNATGGAR AARAARGCNATHACNMGNCARTCNCCNGCNCCNAGYCARTCNMGNAAYGGNGGNGTNGCN AGYGARMGNAARTCNGAYTTYACNCCNAAYMGNMGNGGNAAYAAYMGNMGNTCNGGN--- ---TCNAAYGGNGGNGCNAARGCNCARGAYGGNCARACNCCNMGNCCNAGYCCNATHAGY AARTGGGAYMGNTCNGTNGGNAAYMGNMGNCARMGNCARMGNAAYGGNTAYGAYTAYMGN CARMGNGARGARGTNGARGARCCNGAYGAYGTNTTYGAYGTNYTNAGYACNGGNTCNMGN AARGGNAAYYTNAAYCAYYTNYTNAAYTTYAARTTYYTNCCNMGNMGNCARAGYCAYCAY GAYGAYTCNMGNTGGAAYAGYCAYTAYAGYTCNCAYGGNCAYGGNGGN------TAYMGN AARMGNAARMGNTAYAARAARGARCARTTYYTNCARGCNAGYTGYCARTTYGTNGTNMGN GAYACNGGNGAYTAYACNGARCARGCNATHAGYTCNGAYGCNYTNGTNGAYTGGAAYYTN ATHGARYTNGTNMGNAGYTTYTCNACNGARACNGTNAAYTGYCCNATHTGYYTNGARATG CCNACNGCNGGNAARATHACNAARTGYGGNCAYACNTAYTGYTGGGCNTGYATHYTNCAY TAYYTNAARYTNGGNGARGGNGARGCNMGNAARTGYCCNATHTGYTAYGARACNGTNGAY ACNGARGAYYTNAARAGYGTNCARTGGATHGAYGTNCCNAAYTTYAARGTNGGNGAYACN ATHGAYATGMGNYTNATGMGNAARACNAARGGNAGYGTNATHACNYTNCCNAARGAYCAR TGGGARGAYMGNYTNGGNAARCCNATGAAYATHCARGARGGNCCNAAYACNGARTAYATG AARYTNYTNGTNGCNTCNTCNGAYCARATHCARACNGARGTNATHGARYTNGARMGNGTN GCNYTNACNTTYCARYTNGARGARGCNGARGARTCNGARGCNTGYTTYATHCARATGGCN YTNGARTAYYTNGARGCNMGNGARAARTCNYTNCARGTNTTYCARCARACNGCNCARACN AARCCNGGNYTNTGGTCNAAYGAYGCNGAYAARGCNCARGAYGARGCNGARYTNACNCCN TCNTCN---------YTNACNTCNGCNGARGAYAAYTCNAAYGARAAYATHGARAAYGAR GGNATGAARAAYAARACNACNGAYYTNTCNGCNTCNGCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GAYTCNCARTCNYTNMGNCARMGNCAYGAYAGYGARTGYTCNYTNCCNTTYGGNTCN CCNCCNTCNCCNTTYCCNYTNATGCCNGAYCARGARGTNAAYCCNGTNCCNYTNAGYYTN GARGARACNGCNGAYCAYYTNGARYTNCCN------ATHGAYATHCCNCARATGGCNACN AARCARTTYCARAARAAYAAYGCNAARGAYGAYTAYATHTTYTAYCARGCNTCNACNGGN CARCARATHTAYYTNAAYTCNYTNAAYGCNCARTGYATGGCNMGNGARTAYGGNTCNYTN GARGAYAGYCCNAAYACNATHCARGGNTCNATHGTNGCNATHGARMGNATHTTYATGACN GARGAYGTNMGNAARMGNYTNMGNTAYYTNGAYCAYATHCCNYTNACNTGYGARGTNCAY ATHGTNGARYTNAARYTNAARCCNCCNGTNGTNAGYAARGARACNYTNAARYTNTTYGAR GCNGCNTTYGAYAARAARMGNMGNCAYMGNCARCARAARGAYMGNGARGAYAARCARMGN GCNAARAARATHGARATHGARCAYMGNAARAGYATHGGNATHTAYCCNGARGTNCARATH CCNYTNGAYAGYTAYGARCARTTYCCNTCNCAYYTNTCNGCNAGYATGAAYGTNYTNGCN CCNATHMGNCARTGGYTNMGNCARTCNTAYAAYGTNGARGTNGCNGARGAYTGGYTNACN ACNTGYGTNGARTTYYTNCAYCARGARACNCARAGYTCNAGYCCNAGYYTNGARGARTTY AARGGNYTNGTNTTYGARCARTGGYTNGGNTCNGAYYTNGCNGARATHGGNAARCCNTCN YTNCCNGAYAAYGTNTTYACNTGYGARAARTGYTTYYTNGAYCAYATGTAYCCNYTNCAR ATHATHTCNATHATHGAYGTNGCNACNCCNYTNTTYGGNCARYTNCARAARTTYCARACN TCNGAYATGCCNCARACNCARAAYACN---TTYAAYAAYTCNTCNGCNCCN--------- ---------------------MGNGCNTCNMGNATGYTNAARYTNGARYTNACNGAYGGN ACNMGNACNGTNCARGCNATHGARTAYMGNCCNATHCAYACNYTNAAYTCNGAYYTNCCN GCNGGNACNAARGTNGTNATHAARGGNGGNGTNYTNTGYMGNMGNCARGTNYTNYTNYTN GARGCNGAYAAYGTNTGYGTNYTNGGNGGNGARGTNGAYGAYYTNATGATGGTNAAYAAY CCNYTNGAYAAYYTNCARGCNGARATGGAYMGNAAYMGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATHACNYTNYTNGAYYTN CCNTGGGARCARGTNYTNTGYMGNAAYGTNYTNCCNCAYYTNAGYATHACNCARYTNTTY MGNYTNMGNGCNGTNAGYCAYGGNTGYATGTGYYTNGTNGAYACNTAYTTYAGYYTNCAR TTYCAYYTNAAYATHTGYCAYYTNGGNAARAARYTNACNTCNACNGCNTTYTCNYTNATG ACNMGNGAYAGYMGNTGYYTNAARACNYTNYTNYTNMGNGGNGCNAARTAYGGNYTNAAY AAYGAYGTNTTYYTNCCNGTNYTNTCNAAYAAYTCNMGNYTNGARAARATHGAYATHAGY GGNTGYACNTCNYTNTCNGGNTGYGTNYTNTAYGCNATHGGNGTNAAYTGYCCNAARYTN AARCARYTNATHGTNMGNGAYTGYGTNACNTTYGTNGARGARAGYTTYYTNTCNTTYYTN TGYGTNAARCARCCNGTNAAYYTNGARTAYYTNGAYATHTCNGGNTGYTGGAAYYTNGGN GAYGAYYTNYTNATHAARYTNGTNGARMGNTGYCCNAAYATHAARCAYYTNYTNYTNGGN AAYYTNTAYGGNYTNACNGAYMGNACNATHTGYGCNATHGCNCAYTCNTGYACNGAYYTN GTNTCNYTNAGYATHGTNGGNTGYTGGMGNATHACNGAYCAYTCNATHAGYYTNATHGCN GCNTAYTGYCCNAAYYTNAARYTNYTNGAYGTNAARGARTGYMGNGAYATHACNGARGAR AGYYTNGGNCCNYTNMGNAARMGNCARGTNAARATHGAYAARCCNGGNCCNCCNCCNTCN TAYATHAAYMGNYTNGARTTYYTNAAYAARGCNCAYAARATHAAYGTNATGYTNGAYAAR GTNGTNYTNTAYAGYTAYTTYMGNAGYTCNTGYAGYTGGMGNGTNMGNATHGCNYTNGCN YTNAARAARATHCCNTAYGARTAYGARGCNGTNCAYYTNGTNAARGGNCARCARMGNACN GAYGARTAYAARATGATGAAYTCNTCNGGNTAYYTNCCNACNYTNAARATHGAYGGNYTN ACNYTNACNCARTCNYTNCCNATHYTNGARTAYYTNGAYGARMGNAAYCCNGARCCNGCN TTYYTNCCNAAYAAYAARGCNGAYMGNGCNCARGTNMGNGCNATHGCNGARATHGTNAAY AGYGGNATHCARCCNYTNCARAAYYTNAARGTNYTNCARAARGTNGGNGARACNAARATG GARTGGGCNAAYCAYTTYGTNACNGCNGGNATGGARGCNYTNGARCCNGTNYTNGARAAR ACNGCNGGNACNTAYTGYTTYGGNGAYCARGTNACNYTNGCNGAYYTNTGYYTNGTNCCN CARGTNGCNAGYGCNGTN---MGNTTYAAYGTNGAYATGTCNMGNTTYCCNACNATHTCN MGNGTNAAYAARGCNYTNGARGARYTNCCNGCNTTYAARGTNGCNGAYTCNMGNMGNCAR CCNGAYACNCCNGARGARATGAARATHGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGTCNGAYAARYTNAGYACNMGNGTNATHCARGTNACNAAY ATHGCNCCNAGYTGYTCNAARGARCARYTNMGNACNYTNTTYGGNTGYYTNGGNMGNATH AARGARYTNGARATGTAYCCNCCNGAYGGNGCNGAR---GGNGTNGTNACNGCNMGNGTN TCNTAYATHGARTTYGARGAYTCNGTNACNACNGGNGTNGCNYTNCAYYTNAAYAGYACN GTNTTYATHGAYMGNGCNATHATGATHGTNCCNGTNATGGAYGGNAARATHCCNGAYGAR AGYTCNGCNYTNCARYTNACNCCNTCNGCNGTNGCNGGNATGYTNCCNGGNCARCCNACN TGGCCNGCNAAYGTNGTNTCNCARGTNACNGGNYTNGGNGCNAAYCARATHATHATGACN AAYGAYCCNMGNYTNACNTCNYTNGGNYTNCCNCARTAYCCNCCNYTNCCNGCNACNACN GAYCCNAGYAARATHGARGARATHMGNMGNACNGTNTTYATHTCNGAYYTNGAYGCNAAR GTNACNCCNGARATGYTNYTNTCNTTYTTYTCNCARACNGGNGARATHAARTAYATHMGN ATGGCNGGNGAYGARAAYGCNCCNACNMGNAGYGCNTAYATHGARTTYACNGAYCARMGN TGYATHGCNCARGCNYTNAGYTAYAAYAAYGTNGTNTTYCARGGNMGNACNGTNAGYGTN AARCAYGCNACNACNAGYATHGTNAARCCNACNCCNMGNTCNGARGCNTCNCARMGNGAR ATHGAYGAYGCNATGAARAARGTNAARGARGCNTCNAARYTNATHTCNGCNGCNGCNAAY AGYGAYMGNGARAGYTCNMGNTCNCCNGCNMGNAARMGNTCNMGNTCNAARGGNMGNAGY MGNTCNMGNTCNMGNTCNMGN---MGNMGNTCNMGNTCNMGNTCN---CCNMGNMGNMGN MGNMGNAGYAGYTCNMGNTCNMGNMGNMGNTCNMGNTCNMGNMGNMGNTCNCCNAARMGN TCNMGNACNCCNGTNMGNMGNMGNMGNTCNMGNTCNMGNGGNMGNGTNCCNCCNCCNGCN CCNACNGTN------------GCNMGNGAYMGNMGNMGNTCNMGNACNMGNTCNCCNGTN MGNMGNMGNMGNTCNMGNTCNAARTCNMGN---------MGN---TCNMGNACNCCNCCN AARTCNTAYAGYMGNGGNMGNMGNTCNCAYTCNMGNAGYMGNMGNAGYMGNTCNMGNGAY MGNMGNGAYAARAARGARMGNAARAARAGYAARTCNATGTCNCCNCCNACNYTNATHMGN GARGGNTCNGCNTCNCAYGARGARGAYMGNGAYAARACNAARGCNAAY------GCNGGN TCNCCNAGYCCNCCNMGNCCNAARAARMGNAGYYTNACNCCNAARMGNMGNAGYAARTCN MGNTCNCCNAGYMGNMGN---AARAARMGNMGNCAYTCNMGNTCNCCNTCN---MGNAAR MGNTCNMGNTCNMGNAGYGGNTCNAARCAYMGNTCNMGNMGNGAYMGNAARMGNAGYMGN AGYMGNGAYMGNAARCAYGAY---AGYAARAARAARAGYAGYMGNGAYAARGARGAYMGN AARAARGAR------AGYAGYTCNAARATHAARMGNGAYTAYGAYGARGARGARAARGGN TTYGCNAGYGAYMGNAGYGAYGARMGNGAYAAYAGYGARGGNCCNMGNTCNMGNGCNGAY TCNCCNAAYGARCCNCCNYTN------YTNGARAARGAYACNGAYAAYCARCCNGTNGAY ATGGARATGAGYGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GAYGCNTAY GAYMGNTTYMGNAGYACNGTNGARAAYTCNATGGGNCAYGARYTNAGYTGGAAYACNATH GCNYTNYTNTTYTAYGCNACNAARGGNGTNGTNTCNGCNGTNGGNAARAGYTCNAARGTN GCNACNCARGCNAARGARTTYACNYTNAARTAYATHAGYGAYACNTTYGTNTCNTGGATH ATGGARCARGGNGGNTTYGAYAGYATGYTNAGYGGNAGYGARTCNAAYTCNGAYYTNGAY TAYGAYGGNGAYYTNCARAAYCAYGGNAARYTNAARGGNTCNYTNTCNYTNAAYTCNATG AARATHGTNMGNGARGTNGAYGAYAARAARYTNGARGAYMGNTGYAAYGTNTTYCARATH GTNTAYGARGAYAARAARGAYTTYCCNATHYTNTAYATHATHGCNAARACNGAYATHGAY MGNCARGCNTGGYTNAARGCNATHGARGARGARGCNGCNMGNTGYGGNGCNCARTTYTTY GAYAARTAYCAYCCNGGNGTNTGGACNAARAARYTNGGNTAYTAYAAYTGYTGYGAYCAR TGYGAYMGNAAYGCNATHGGNTGYAARAGYGAYMGNATHGTNCARAARGGNCCNYTNCCN CCNATHCCNCCNCCNMGNCCNGARTCNAGYAGYMGNYTNGARTAYATHGCNYTNTTYGAY TAYGAYCCNCCNGARGTNGGNGAYYTNGARYTNYTNCARGGNGARAARTAYATHATHYTN GAYAARAGYGCNGARAAYTGGTGGTAYGCNGARAAYMGNGARGGNMGNAARGGNTAYATH CCNGCNAAYTAYGTNAARATHAARTTYGGNYTNGARCARTAYGARTGGTAYTAYAARGAY TGYAGYMGNGARMGNGGNACNTAYATHYTNATGCARMGNGGNAARGAYGGNTGYTTYYTN GTNMGNGAYTCNATHAGYTGYCCNGGNTCNTAYTCNYTNTCNATHTAYACNACNGARMGN GARGGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGYTNTCNGTNGTN YTNGTNGCNTCNATGYTNTTYGGNGTNGGNACNTCNCAYYTNTGYATGATHACNCCNCCN CARMGNGGNTCNATHGTNGGNATHAAYCARCCNGGNGCNCCNAAYTGYATHYTNYTNAAR TCNCCNTGYGGNGGNMGNGGN---ACNGGNCCNATHYTNGARYTNATHGCNGGNCARACN TAYACNGTNAAYYTNYTNAARAAYYTNAGYCAYTTYAAYAARGCNAAYCCNGGNAAYTTY ACNATHTCNATHGCNCAYGTNGAYGGNCCNTTYCARTCNYTNACNTCNTTYCCNGAYGAY TCNGARCCNTCNYTNTCNYTNTAYTCNACNAAYGTNACNATGCCNAARGCNATGGGNGAR ATGGTNYTNCARTCNGTNTAYTAYACNAAYAAYGCNAARGCNCCNGCNGCNTTYTAYCAR TGYAGYGAYYTNMGNYTNGTNAGYAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNTCNGCN CCNGTNTTYGGNGCNGGNGCNCAR---AAYTCNACNGCNTTYGGNTCNGCN--------- ------------GGNGGNTTYGGNACNGGNGGNAARCCNCCNGCN--------------- ---------------------------------------------------------AAY CCNTTYGGNGCNCARGGNGCNAAYACNACNCARGGNGGNGCNTTYAGYTTYACNGGNAAY ---CARCCNTTYGGNGCNTCNACNACNAGYACNGCNTCNTCNGGNTTYAAYTTYGGNCAR GCNGCNCARCCNGGNGCNGCNCCNTCNGGNGGNTTYAAYTTYTCNGCNGCNCCNTCNACN CCNGCNAAYAAYGGNGGNTTYAAYTTY---ACNCCNGGNGGNGTNTCNACNCCNTCNTTY AAYTTYGCNGCNGCNCCNGGNACNCCNAAYATGTTYACNCCNCARAAYCCNGGNAAYGCN ACNMGNCCNMGNGTNGCNGCNMGNMGNGGNACNMGNMGNGGN------CARATHTCNCAY ATGATHGCNTTYATHGAYCARGARGCNTCNGARAARGTNGARGARATHGAYYTNAARGCN GARGARGARTTYAAYATHGARAARGGNMGNYTNGTNCARCARTCNMGNGTNCARATHATH GAYTTYTAYGAYAARAARATHAARAAYGTNGARYTNCARAARAARATHCARAAYTCNAAY ATGCARAAYAAYGCNMGNYTNGARGTNYTNMGNAARAARGARGARTAYGTNAARGARGTN YTNGARGARGCNMGNGARCARYTNAARMGNGTNGCNMGNGAYAAYCCNGARGARTAYAAR CAYYTNYTNYTNAARYTNATHATGCARGCNYTNGCNMGNYTNATHGARTCNAARGTNACN ATHMGNTGYMGNMGNGARGAYGTNCARATGATHAARAAYGCNGCNCCNGGNYTNGTNAAR GARTAYAARGARYTNYTNAARGGNAARTAYAGYYTNGARYTNGTNGTNGARGARGARAAR TTYYTNTCNCARGARATHTGYGGNGGNGTNGARYTNCAYGCNATGAGYGGNAARATHGTN ATHGTNAAYACNYTNGAYGARMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNATHGTNTTYATHCARMGNACNGARTCNTTYAGY GCNTGYCAYMGNYTNCAYAGYCCNTAYYTNAGYGAYGARAARAAYGGNATHATHTTYGGN AARTGYAAYCAYCCNAAYGGNCAYGGNCAYAAYTAYAARGTNGARGTNGTNYTNAARGGN CCNGTNGAYMGNGAYACNGGNATGGTNATHAAYATHGTNGAYYTNAARAARTAYATGGAR ATGGCNGARAGYGAYCARCARTAYACNATHTAYGAYGCN---AAYCARCCNYTNACNYTN ACNGTNAGYAAYGTNAAYCARGGNACNGARGARGCNCARGCNGTNCARAGYATHCARTAY ATHTCNCCNGAYGGNGTNCCNGTNACNCARYTNGAYGGNAAYGAYGTNATHCARGTNGCN CARAAYGCNGAYGGNACNTTYCARCARGCNACNACNGCNTTYCARAAYATHCAR---TCN GTNCARCCNCARGTNATHACNAAYGCNGCNTCNGTNCCNATGGTNGCNGCNACNTCNCAR GGNGGNACNATHYTNCARTCNAAYAAYGTNYTNMGNAAYGTNGTNCARCARCARACNGCN CARGTNACNCARCARCARACNATHCARACNGCNGGNACNTCNACNCCNCCNGTNGGNACN AAYGCNGCNGGNATHCCNCARATGYTNTTYYTNAAYCARGTNACNATHAAYGGNCARACN TCNTTYGTNYTNGTNGAYGCNAAYAAYAARCCNATHCARYTNCCNCARGGNATHCARGTN ATHAAYYTNCCNCAYCARCARYTNCCNGGNCARTCNATHCARATGCCNGGNAGYGAYACN GGNGAYGARCCNYTNTAYGTNAAYGCNAARCARTAYCAYMGNATHYTNAARMGNMGNCAR GCNMGNGCNAARYTNGARTCNGARGGNAARATHCCNAARGARMGNCARAARTAYYTNTAY GARTCNMGNCAYAARCAYGCNYTNAAYMGNGCNMGNGGNTCNGGNGGNATHTTY------ ------------------------------------------------------------ ---------------------------GAYMGNYTNACNGTNAAYCAYYTNTGYYTNACN ATHCARCARCAYACNAAYATHGARCCNCARGCNCARAARATHATHTAYMGNGGNMGNACN YTNTTYAARACNTTYAAYCCNGARGAYCCNAAYYTNAARAARAGYYTNTCNTCNYTNGGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GCNGGNGGNGGN AGYACNMGNYTNTTYMGNAARATHAARGAYMGNAGYAGYGTNTAYYTNMGNTTYTGYAAR GTNMGNTCNAARGGNTCNTAYYTNTAYGARGAYTTYATGCCNACNGAYGGNACNGAYGTN AARGTNTAYACNGTNGGNCCNGAYTAYCARCAYGCNGARGCNMGNAARTCNCCNGCNYTN GAYGGNAARGTNGARMGNGAYAARGARGGNAARGARATHMGNTAYCCNGTNYTNYTNGCN AAYMGNGARAARATGATHGCNMGNAAYGTNTGYAARACNTTYAARCARAAYGTNTGYGGN TTYGAYYTNYTNMGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGGGNAARAARCAYAARCAYGGNMGNCAYTCN TCNTCNTCNTCNTCNTCNTCNTCNAGYAGYGAYTCNTCNGAYGAYGARTGGMGNCAYYTN CCNAARCAYGARAARAARCARMGNAARAARTGGAARAARCARATGMGNAARGGNCAYATH AGYCAYGGNACNYTNCCNCCNTGGCARGGNGGNCCNCAYTGGGCNCCNCCNATGAARGGN GGNAARAARGGNGGNAARGCNGGNAARGGNTAYCCNACNGGNGTNCAYCCNCCNCCNGCN GGNTAYCCNGGNCARCCNGGNTAYCCNGCNCCNGGNTAYCCNGGNCARCARCCNGGNTAY CCNGGN---------------CARCARCAYGGN---TAYCCNGGNCARCARCCNGGN--- TAYCCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNGARYTNGAYGARACNAGYGAYYTNATGMGNGGNATHGARTGYGAY MGNGCNAAYYTNTCNCARTCNYTNGARCARCARAGYCARCARYTNGARAGYYTNGAYAAY GAYMGNCARAAYATHYTNAARGARYTNGARTCNGCNTCNGCNGARMGNACNTCNYTNAAY CARGARAAYAARTCNYTNTCNCARCAYGCNGARGTNYTNCARGCNGARYTNCARAGYATH GARGAYAARACNYTNGCNATHCAYGARGARAARTCNACNACNGARGAYAARYTNMGNGAY AAYYTNGARMGNYTNGAYCARYTNGARTTYGARAARACNATGATHTCNGARCAYGCNTCN GARYTNCARGGNACNATHCARGAYYTNGTNTCNCARAARGARATGACNGARAARGARYTN AARGARGARATHMGNGCNMGNATHTCNGCNGARGGNMGNYTNAARGARGCNGARMGNTCN YTNACNTCNYTNGAYCAYGCNGTNCARACNCARTCNCAYMGNATHGARGAYGARGCNAAR GARGARATGAAYGTNAGYGTNMGNAARYTNAARCAYTTYTTYGARGAYYTNGCNGARGAR GCNAARATHTCNTCNGAYAARCCNATHGTNATHMGNAAYGGNYTNATGGCNMGNAARACN YTNGCNMGNMGNGCNAARACNGTNMGNTAYGARAAYMGNMGNMGNTCNTCNYTNTAYATH GGNACNGTNATHGGNAGYATGTTYTGGGGNTGGGTNGCNGAYACNAARGGNMGNAARATH GTNYTNGTNYTNTGYTCNATHYTNGGNGGNYTNAGYATHGTNGGNTTYGGNTTYTCNGCN AAYATHCCNATGGCNYTNGCNATGAARTTYTGYYTNGGNGCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR YTNATHTAYTTYGAYYTNAARGGNMGNGCNCARATHTCNMGNYTNYTNTTYGCNGTNGCN GGNGTNGARTAYGARGAYTGYMGNATHCCNTTYGCNGAYTGGCCNGCNYTNAARGCNACN ATGCCNTTYAARCARATGCCNGCNYTNGARATHAAYGGNAARAARCAYGCNCARAGYTAY GCNATHGCNMGNTAYYTNGCNAAYGARTTYGGNTTYTAYGGNAARGAYAAYYTNGARMGN YTNGARATHGAYCARATHGTNGARCARYTNAARGAYTTYATHTTYTAYYTNGAYMGNTCN TTYMGNGARTCNGAYCARGAYAARAARGCNGARTTYATGAARGARGCNATHGARGTNCAY AGYYTNGCNGCNYTNCAYGTNTTYGARGAYYTNATGAARGCNAGYACNACNGGNTTYTTY GTNGGNTCNAARYTNAGYYTNGCNGAYYTNTCNGTNTTYGAYATHATGGAYTAYATHACN GARMGNAAYGCNACNGCNYTNGAYGAYTGYCCNCAYYTNAARTCNTTYMGNGARAARATH GARAGYATHGAYGCNGTNMGNGCNTAYATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CCNMGNTAYMGNACNMGNTTYCARTCNCCNATGTTYGCNTCNCCNTCN MGNTTYYTNGAYMGNCCNMGNTAYGCNTGGGAYGAYAAYGAYATHMGNGCNTAYMGNTCN GCNTCNACNYTNGCNAAYYTNCCNACNCCNAARCCNGGNTAYGGNCCNTCNTAYATGGCN CCNMGNGCNGCNACNYTNCCNYTNGCNGGNGCNTAYGGNGCNMGNGAYGAYTGGMGNTTY TTYGARTTYGAYGARACNGAYGAYMGNCCNAAYACNAAYYTNTCNTCNTCNACNYTNACN GGNGAYAGYAGYTCNMGNMGNCAYGAYTCNTCNTTYACNGGNTAYGARGGNCCNAAYATH TCNYTNYTNAARYTNCARAARAGYACNTGGCAYGCNGARATHGARCCNGCNATHTAYGAY TAYGARMGNYTNAARATHACNAAYTTYGAYYTNCCNAARGAYGTNGAYACNAAYCAYYTN GARATHCAYYTNACNAAYGARGAYTTYGARGARYTNTTYAARATGCCNMGNGAYMGNTTY TAYMGNATGGCNGARTGGAARMGNAAYGAYGTNAARMGNAARYTNAAYYTNTAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY AARAARATGGAYGTNGAYACNATHAARACNATHGAYGAYGARTAYTCNCCNGGNGTNTTY YTNYTNACNAAYTGGYTNACNGAYCCNTCNCAYACNTCNACNTCNGGNTTYGTNCARTGG AARCCNGTNTCNTAYTTYGGNAARACNMGNGGNMGNAARACNGTNACNAARGTNAARCAY TAYGAYYTNTTYGARYTNGARGARGCNGAYACNYTNAAYGCNACNYTNGTNTCNGCNYTN TTYGGNGAYAAYYTNTTYGGNAARTCNGAYATHAARAAR------ATGAAYATHTCNTTY GGNCARCCNAARGAYGGNTAYTAYYTNAARAAYAAYTAYACNGTNTGGGAYGCNGCNATH GGNTAYGGNACNCCNCCNAARGAYGARATHTCNYTNACNGTNATHATHATHATHGCNACN GGNYTNGGNATHCCNGTNYTNYTNTGYATHGTNGGNGGNGTNTAYACNATH---TCNAAR GTNGTNMGNAARAARAARTCNCARTAYGARGCNATHAAYGGNAGYAGYTCNATHAAYCAR GAYMGNACNCARGTNAAYATHAARATHYTNGARTTYGTNYTNTCNATHTTYGCNTTYGCN ACNACNACNAGYCCNGAYGARTCNACNACNTTYACNGTN---GCNAAYTGYAGYAARTGG ACNYTNAAYAAYACNGGNCCNGTNGCNGTNTCNCAYACNTAYTCNTAYAGYTAYGARYTN GARGARGTNTGYYTNAARYTNCCNYTNTGYAARCARGTN---CCNGTN---------GGN GARGTNTGYYTNYTNGARGGNTCNAARTCNTCNGCNCARTTYTAYGTNTTYGTNGGNGTN ATHGTNTTYYTNTAYTGYYTNGCNACNYTNGTNYTNTAYGTNTTYTTYGAYGARYTNTAY MGNMGNAAYTCNMGNATHGTNYTNGTNGAYTTYATHATHTCNTGYGTNYTNACNYTNTTY TGGATHATHTCNTCNTCNGCNTGGGCNTCNGGNGTNGCNGAYGTNAARATGTAYACNGAY CCNTAYGAYGGNGGNATHYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CCNAGYTGYATHACNGAYYTNCCNCARGAYTTYGAYTTYCAYTGGTCNTCN ACNAAYCARYTNGGNGAYYTNGTNATHCARTTYGARGCNAAYYTNGGNAAYTAYCARGAR TTYTGGAAYATGGCNGARGARATHGAYAARAAYACNTGGGTNYTNGARCCNGARCAYCCN ACNTAYTCNTGYGCNTAYMGNMGNATHGCNYTNGGNCARAAYYTNTCNYTNCAYATHGTN ATHAAYCCNYTNCARCCNTCNAGYYTNCCNGARTGYMGNATHYTNGGNGCNGARTCNGTN GTNGCNCCNYTNMGNGARAARYTNAAYGTNAAYYTNCAYYTNTGGGAYYTNGAYMGNTCN YTNYTNAAYAAYYTNCARGARGTNYTNGARATHGAYTTYCCNTCNCCNTCNGAYACNAAY AARGARGARYTNAGYGTNGAYTGYGGNATHTGYTAYTGYCAYCAYYTNGARGARGARATH CCNGAYATHGTNTGYCARTAYGTNCAYTGYAGYCARTCNTTYCAYTAYACNTGYYTNTAY GARTGGYTNMGNAAYTCNTCNTCNMGNCARAGYTTYAAYTAYATHTTYGGNGARTGYCCN TTYTGYAGYAARCCNATHMGNGTNAARATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CAYCAYCAYCAYCAYCAYCAYMGNCCNCCNCAYCAYTAYYTN CAYCARMGNGAYMGNGCNGGNGAYATGCAYGGNCCNGGNATGGGNGGNGGNGAYGTNTCN GGNYTNGAYGCNGCNAARMGNAARGCNYTNCCNYTNTGGYTNMGNGARGGNYTNGARAAR ATGGARMGNGARAARCARAARYTNATHGARAARGARCARYTNAARAARAARCARAARGAR YTNTAYGCNATGCARGARGAYTCNGTNAARGARAARGGNACNGARGARGARGARGAYGAY GAYGGNCARCCNAARGTNCCNMGNAARAGYMGNTTYGAYTCNGAYGAYGAYGAY------ ---GAYGARGAYAARAARGARGAYGARGAYGARGTNGAYGGNAAYAGYGAYGTNGARGCN TCNAARCCNCARCARCARCARCARCARGARCARGTNTCNAARYTNTCNCCNCCNMGNAAR MGNAGYCCNTCNCCNTCNGARTAYATGACNGARGARGARMGNGARGCNGCNATGATGATG AARGTNAARMGNATGYTNACNGARACNYTNYTNGARGTNACNGAYAARGARATHMGNAGY ATHGCNTCNGARGTNTAYCARAARGARMGNAARAARGCNCARAARGCNCCNGCNAARCAR YTNGCNAARTCNTCNGCNYTNGCNTCNATHTCNAGYYTNGGNYTNGGNTAYGGNTCNGGN TCNGAYAGYGAYGARGAYGAR---------------AARGARGAYTCNGAYAAYGAYYTN GARGAYMGNATHAARMGNMGNAARGCNGARTTYGCNAARAGYCARAAYATHTTYAGYGAY TCNGARGAYGAYGAYATGAARGCNGAY---MGNGAYAAYMGNAGYAARAAYAAYMGNGAR GAYGTNAARTCNGARAARGTNMGNGAYAARGAYGAYMGNMGNCARTCNGAYMGNMGNGAY TCNAARAGYGAYMGNMGNGAYAGYAARGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTAYAAYGGNATHGGNYTNCARACN CCNMGNGGNAGYGGNACNAAYGGNTAYGTNCARMGNAAYYTNGCNTTYGTNAARTCNAAR AARGAYMGNGTNGAYTAYAARGAYGARGARGARYTNAARAARYTNGARCARTCNATGAAY AARCARCCNAAYCARGARATHYTNGAYCAYGARMGNAARMGNAARGTNGARYTNAARTGY ATGGARATGCARGARYTNATGGARGARCARGGNTAYACNAAYAARGARGTNATGGAYAAR GTNAAYATGTTYMGNAARATGYTNATGGCNAARGARGGNGTNTCNGAY---ACNCCNATH GARAARGAYGARCAYGGNMGNCCNATHGCNAARGARACNCAYCARYTNGCNGARGCNAAY CARATHAARAAYGAYAARYTNAARGARGCNTTYGGNYTNTCNGARTAYACNGARGGNAGY GCNTTYGAYCCNGAYMGNAARGCNAARGARGARCARGCNAARGCNYTNGCNYTNGCNCAR AARAARTAYAGYATHGTNAAYAGYTCNGAYGARGAYAAYGCNAAR---GARAGYTCNCCN GTNCCNAARAARAARAARAARAARTCNMGNCAYGAYGAYGCNTCNTCNCCNGARMGNAGY AARGARAARMGNAARAARAGYMGNAARCAYAGYAARMGNGAYMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGATHTCNGAYYTNCARTCNCARTCN AARAARAAYCARGCNATHGCNGAYCARGCNTGGGAYAARGTNMGNGCNACNGGNAGYGTN CARCAYGGNYTNGARACNGARGTNGTNGARYTNMGNMGNGARYTNGCNGARTCNCARGTN CARGCNTCNTCNYTNYTNTCNGCNTGYGCNYTNYTNAGYGGNGCNYTNTAYCCNYTNTAY ACNAARGCNGCNATGYTNTCNTCNCARMGNCAYATHYTNGARGAYYTNTTYTGYAAYTGG GARAAYTGYMGNGAYMGNGCNATGTAYYTNTGYTCNGTNYTNAGYTCNGGNMGNGARAGY GARCARGAYCARCCNGARMGNGAYAGYMGNTTYCARMGNAARMGNAAYCCNATHYTNMGN TTYMGNATGGGNGTNATHGCNGTNATHGCNGCNCAYMGNYTNGCNTAYYTNGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GAYAAYCCNTTYATHAAYGCNGAYATHATHCAYGAYTAYCAYGAYTAYTAYAAYACN AARGCNGTNAAR---GAYGARGGNAAYAAYTAYTAYGTNGAYATHTCNACNGCNGGNAAR CAYGARACNYTNTCNAARAAYCAYMGNGTNGCNGCNGTNATHCCNYTNAARTTYGAYTTY CCNTTYTAYGGNCAYCCNGTNATHAAYGTNACNGTNGCNACNGGNGGNTTYATHTAYATG AGYCCNTTYYTNCAYCARTGGYTNACNGCNACNCARTAYATHGCNCCNYTNATGGCNAAY TTYGAYCCNTCNYTNAGYGCNACNTCNAAYATHTTYTAYYTNAGYGARGAYGARATHTTY ACNGTNGARTGGMGNGAYGTNYTNYTNCARGAYCARGARGAYGTNGGNGGNTTYACNTTY CARACNTCNYTNCAYAGYAAYGGNACNATHAGYTTYGTNTAYAARAAYATHCCNYTNCAY GCNGAYAARATHTCNGAYGARAAYCAYCCNGTNAARGTNGGNYTNTCNGAYGCNTAYTAY AAYGAYACNTAYYTNMGNCARTTYGGNATHMGNMGNMGNACNATHTAYGARTAYCAYCAR GTNGTNYTNGARAARGGNYTNGTNAARACNGGNGCNGTNATHTTYATHGAYCCNGTNCCN ACNTGYAAYACNYTNAGYGAYTGYGARACNTGYACNGCNCAYGTNAAYGTNGARTTYGAY TGYYTNTGGTGYAAYACNATHGGNMGNTGYTCNGAYGGNYTNGAYTGGTAYMGNCARCAY TGGGAYAARTAYTCNTGYCAYAARYTNAGYACNAAYCARACNATGGARTGYGCNGGNYTN CCNCCNCCNACNATGCAYATHGCNCAYCCNATHACNCCNYTNGARCCNGARAARAARACN TGYAARGGNGGNAARTGYGGNGAYGGNAARGAYGTNCCNGTNGCNGTNATHGTNGTN--- GTNYTNYTNYTNGTNYTNGTNYTNATHGGNTCNGTNGGNGGNTGGGTNTAYTAYGCNTAY ACNCAYCCNACNTCNAARTCNGGNATGTGGYTNATHCARCAYMGNCCNAGYCARATGAAR GCNAARATHCARTTYTGGAARAGYAGYAGYAGYAGYTCNGCNAARTAYMGNACNGARACN GAYGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYATHMGNAARCARMGNGCNGARATHTCNACNTGGYTN TCNTCNGTNYTNGARCAYGARCCNATHCCNGAYTTYGARATGACNGCNCARACNYTNCAR ATHYTNCAYMGNYTNTCNGTNGTNAGYCARTTYAAYGARAARAAYGCNCAYYTNTGYATH GARGAYYTNAARAARAARTCNGARGARTAYAAYGCNGAYGCNCARMGNATHGGNAGYGTN YTNGAYMGNYTNACNYTNGGNCARAAYAGYYTNTCNMGNTCNGGNTCNTCNTGYATHCAR GCNYTNTCNMGNACNGGNGCNTCNYTNGGNGTNGTNGAYGCNTCNGAYACNTGYTAYYTN YTNTCNYTNMGNGARYTNMGNTCNAGYGTNAAYGARYTNGCNGARAARYTNCARTCNGAR AAYCARGARATGCARMGNYTNTCNMGNAARACNCARTCNGTNYTNATGCARCAYAAYTCN YTNGARAARGCNYTNGARGTNYTNGARAARMGNGCNACNCARAARACNGCNCARATGGCN GARMGNAARAARGARACNGCNATHYTNAARAARGTNACNGCNGARAAYGARATHACNGTN GARAARYTNAARACNAARYTNGCNAARTCNGGNGTNAGYAARTCNGAYTTYCAYGAYGTN YTNGTNAARAARAARGARAARYTNGAYGCNACNGARAAYGARYTNGCNCCNYTNMGNYTN GARYTNCARTCNTAYACNAGYYTNCCNCCNGAYGCNGTNGARACNAARGTNAARATHGAR CARYTNAARMGNGARYTNTCNCARYTNCARGCNCARATHGCNGARAGYGTNGAYGTN--- ------------------------------------------------------------ ---------------------------------------TGYCCNAGYCCNGGNAGYCAR GAYAGYTTYGAYYTNAAYCARTAYYTNGGNAARTGGTAYGARTAYGARMGNTTYAGYGCN TGGTTYGARYTNGGNGTNGTNTGYGGNAGYGCNGARTAYGGNYTNAAYGAYGAYGGNTCN GTNAGYGTNACNAAYGGNGGNTAYMGN------AAYGTNTTYGGNTAYAARATH------ ---CCNACNTCNATHACNGGNAARGCNACNATHCCNGAYCCNTCNMGNCCNTCNGARYTN MGNGTNTCNTTYTCNMGNTTYGAYMGNTCNACNGGN---GGNCCNAAYTAYTTYGTNGTN GARACNGAYTAYACNAGYTAYACNGTNGTNTAYTCNTGYACNGAYYTNCCN---YTNGGN TTYAGYAGYCARYTNGCNTGGATHYTNACNMGNGAYMGNGGNGTNGTNCCNTCNAAYATG GCNGCNATHAARTCNATGYTNCARTCNAARGGNGTNGAYGTNACNAARTTYAAYTCNGTN GAYCARTCNGAYTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYGAYTGGACNYTNTAYTGGACNGAYTTYTCNGTNGCNYTN GARMGNGTNATGGARATGAARAAYTAYCARAARATHAAYCAYTTYCCNGGNATGAAYGAR ATHTGYMGNAARGAYATGYTNGCNMGNAAYYTNAAYMGNATGCARAARATGTTYCCNAAR GARTAYAAYGTNTTYCCNAARACNTGGTGYYTNCCNGCNGAYTAYGGNGAYTTYCARGCN TAYACNMGNCARAARAARAAYAARACNTAYATHYTNAARCCNGARTCNGGNTGYCARGGN MGNGGNATH--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNATHMGNMGNYTNGTNGGNGGNCARCCN YTNTCNMGNGGNGCNTGGCCNTGGYTNGTNTCNYTNAAYTAYYTNGGNCAYCAYGCNTAY ATGGARYTNCARGGNYTNGAYCAYYTNTGYGCNGGNGCNYTNATHGARCCNCARTGGGTN YTNACNGTNGCNCAYTGYGCNCAYTCNYTNYTNGGN---GCNGGNATHGARGAYCCNTCN AAYTGGATHGCNGTNGTNGGNGARTAYCAYMGNMGNMGNGTNGARTCNACNGARCARMGN ATHGARGTNGARGCNAAYTTYYTNAGYCCNGTNTTYTCNTAYCAYCCNAAYTTYACNGGN GAYATHGCNYTNYTNAARYTNMGNCAYCCNGCNMGNATGAAYMGNGAYGTNGCNACNATH CCNYTNGAYTAYGGNATGATHATHGGNAAYGGNGAYTCNTGYCARGTNGCNGGNTGGGGN CARACNCARGARGCNAAYGARGGNGAYCCNCARTTYGGNAAYGGNACNATGATHCCNTAY GTNGCNACNYTNMGNMGNGAYGAYCARCARGAYTGYMGNAARCARTAYAGYCCNACNTTY TTYAARATHGAYGAYTCNATHYTNTGYTTYTCNTCNGAYGAYATGAGYGAYACNTGYCAR GGNGAYTCNGGNGGNCCNYTNYTNTGYCARACNGGNAGYGGNAAYAGYGTNYTNGCNGGN GTNGTNTCNGCNGGNGCNGGNTGYGGNMGNAARGCNATGCCNGGNATHTAYACNMGNGTN TCNCAYTAYGCNGAYTGGATHMGNGGNACNATH--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARATHCARGAR AARAAYATHMGNYTNTGGCAYGTNTGGCARGAYCCNAARGAYCAYMGNCCNAAYGAYTGG ACNTTYCCNGGNGARACNATHAARMGNGTNAGYYTNTAYAARMGNGAYGCNMGNGCNGCN TTYYTNTAYGTN---TGYAGYMGNGTNAARCCNNNNNNNGTNNNNYTNCARGGNYTNGAY NNNGCNGGNAARACNACNYTNYTNTAYNNNYTNAARYTNGGNGARNNNGTNACNACNATN CCNACNNNNGGNTTYAAYNNNGARACNYTN---CARAGYTCNNNNYTNGARGTNACNGCN TGGGAYNNNGGNGGNMGNNNNNNNNNNMGNNNNYTNNNNMGNCAYNNNTAYNNNNNNNNN GAYGGNTTYATHNNNNNNYTNGAYAGYNNNGAYGTNGANMGNYTNGAYGAYGCNTTYGAR GARYTNNNNNNNNNNATHYTNAARGAYGAYGANNNNMGNGAYNNNGTNGTNATGGTNYTN GCNAAYAARCARGAYYTNGARAAYGCNYTNACNCCNGCNGARATHGARNNNMGNYTNNNN AARNNNNNNNNNNNNNNNNNNNNNACNYTNTTYGTNATGCCNTGYAGYTCNACNTCNGAY GAYAAR------NNNATNNNNYTNGCNTTYNNNNNNTTYGTNNNNATGATHNNNNNNAAR AARGARGGNACNYTNGARAAYNNNTTYATHCCNTCNGCNNNNNNNNNNNNNCANGANNNN NNNAANNNNNNNACNNNNNNNNNNNNNNNNNNNAAYTCNNNNTTYAARNNNCCNTTYCAY NNNATNAARTCNGTNYTNTTYTAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AGYGGNYTNATH GGNMGNAGYTTYACNATGATHTTYGCNAGYGCNGGNTAYGAYGTNACNATHTTYGAYYTN GARCCNAARCARACNTCNGCNGCNAARGCNGAYATHCARGCNCARYTNTCNAAYYTNGAR AGYCARGGNYTNYTNMGNGGNGCNYTNTCNAARGARGARCARTTYAAYAARATHTCNACN ACNGARAGYYTNGARGARTGYGTNAARCAYGCNTTYTTYATHCARGARTGYGTNCCNGAR CARYTNGARATHAARMGNTCNGTNTGGTCNAARATHGAYAARATGGTNGCNGGNGAYGTN ATHATGTCNTCNTCNACNAGYGCNYTNYTNCCNTCNGCNATHTCNGAYGGNYTNGARCAY AARAAYMGNTTYATHATHTCNCAYCCNACNAAYCCNCCNTAYTAYGCNCCNGCNACNGAR GTNGTNCCNGCNGGNTGGACNGAYGCNGARGTNACNACNMGNACNATGGARGTNYTNMGN GARGTNGGNCARGTNCCNATHYTNGTNAARAARGARATHGAYGGNTTYGTNYTNAAYMGN YTNCARTAYGCNATHATGGGNGARGCNTAYAARYTNATHCARGAYGGNGTNGTNAGYGCN ACNGAYYTNGAYYTNATHATGTCNCARGGNYTNGGNATGMGNTAYGCNTTYATGGGNCCN TGGGARACNGCNCAYYTNAAYGCNGARGGNATGYTNGTNTAYGGNGAYMGNTAYGCNGAY ATGATHATGGGNATHCARCARACNTTYACNCCNCCNCARMGNATGGARGGNGARACNYTN AARGCNATHCAYGARGAYATGYTNAARACNGCNGGNCCNYTNGARGAYATHCARGCNMGN MGNCARTGGMGNGAYMGNMGNYTNGTNGGNYTNGCNCARYTNAARMGNAARYTNGAYAAR GCNGAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNACNTGGTGYMGNAAYGTNGTNYTNACNMGNGCNYTNMGNCAR GAYGCNGAYYTNGAYYTNCCNCARGAYCCNGAYAGYGGNAARCCNCAYMGNYTNGTNGTN GAYGCNGARACNAGYATHMGNTAYATGGAYAGYCARGCNTTYGTNGARGGNTAYGGNGCN AARCCNGTNTGGTTYCAYTAYMGNMGNAAYTTYAARGGNGGNTTYATGCCNCCNACNMGN AARAARTGYGTNMGNAARGGNGTNYTNGCNACNTCNAGYCCNTGYCCNGTNTGYMGNGAY GARTAYYTNGTNYTNGAYGCNAARAAYACNAARYTNYTNTCNCARTTYGTNAAYCCNAAY ACNGGNGARATHYTNGAYTCNATGAARACNGGNYTNTGYCARGARCARCAYMGNAARYTN ACNGTNGARGTNATGMGNGCNTGGGAYCARGGNTAYATHGARATGGARGTNCCNTTYMGN ACNTAYGAYTAYGAYGAYTAYAARACN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MGNAAYATH AARCARAARTTYMGNGCNYTNYTNAARAARTTYAARATHTCNGARGAYGCNYTNGTNGAY TCNGARGCNGAYCAYGAYCARATGCCNAAYCCNYTNGAYGARYTNTTYGAYGARYTNGAY GAYTCNGAYTCNGGNCCNGARYTNGAYACNATGAGYGTNATGTCNACNCCNAARCCNAAR YTNMGNCCNTTYTTYGCNAAYMGNGGNAAYACNCCNGGNATHGCNGARATHCCNAARACN ACNTCNCARGARGCNTTYMGNTCNCARGARGARACNCCNGTNAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CCNTAYGARMGNGTNGTN TTYGTNGAYTGYAARTGGAAYCARACNAARCARATHGTNAAYGAYGARMGNYTNCARGGN YTNAARAARGTNGARYTNAARTCNCARTTYACNAAYTTYTGGMGNAGYCARGARGGNATG CCNAARACNTAYYTNTCNACNATHGARGCNATHTAYTTYTTYTTYAARGAYTTYCAYTCN ATHTTYGTNGAYCCNATHTAYMGNCAYGARTAYGAYAAYYTNYTNATGTTYTTYTGYTTY ATGTAYCAYAARATHAARMGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TTYAARCAYTAY ATHYTNTTYYTNATHCAYGAYTGYMGNAGYMGNTCNGCNCCNGTNAGYCCNAAYMGNTTY ATHATGYTNGTNATHGGNAAYATHATHAAYTGGACNTTYGCNYTNTAYGGNGCNATHAAY CARCCNTCNGAYTTYGCNAGYTAYYTNYTNGCNATHTTYATHGGNAAYYTNYTNYTNTAY TGYYTNTTYTAYGTNATHATGAARYTNYTNAAYGGNGARAARATHAAYYTNYTNGTNATG GTNGTNATGYTNATHTGYYTNGCNYTNTGGGGNGTNTCNYTNTAYTTYTTYTTYCARCAY GTNACNTCNTGGCARAARACNCCNTCNGGNTCNMGNGARGGNAAYMGNGARTGYATHYTN YTNAAYTTYTAYGAYTCNCAYGAYGTNTGGCAYTTYYTNTCNGCNTTYAGYYTNTTYTTY TCNTTYATGATHYTNYTNYTNYTNGAYGAYGAYATHTCNYTNMGNCCNMGNACNCARATH CCNGTNTTY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNAARGARGTNCARGARGARMGN GAYAARYTNYTNACN------GAYCARGARAGYATGAARATHAARGAYYTNCARGARMGN ATGGCNGTNYTNGCNMGNGARAAYGARGARAARGARCARATGATHTAYAARYTNAAYGAY GARYTNAARGCNACNAAYYTNAARYTNMGNGAY--------------------------- ------------------------------------------------------ATGTCN AAYACNCARAGYACNTAYGCNYTNTTYTAYAARGCNYTNAAYACNTTYTCNAARGAYATH CCNYTNCAYYTNAARTCNGAYGCNCCNGCNGTNYTNTCNTCNAAYATHGGNGCNGTNGCN TAYATHATHACNCCNTCNGAYAGYGTNTTYGAYGAYTAYGAYGTNGARGARATHAGYAAR MGNGTNATGYTNATHACNGARGGNTAYGTNAARMGNYTNGAR---GAYTGYCAYCAYGTN YTNGAYGAYAGYATHAGYTGGTTYAAYAGYCARAARGARGCNYTNATGTTYACNACNACN ATGACNAARATGTCNYTNAGYAGYYTNGGNYTNGGNGAR---CAYGAYGTNAARGTNGGN GAYGCNGGNATGGGNGGNYTNAAYACNGGNGTNTCNAAYAGYATHTCNCCNGCNGTNYTN GGNCARYTNAARGAYYTNATHGAYGGNYTNCARYTNTCNACNTTYAARAGYAAYYTNAGY YTNGAYAARATGTAYCCNGAYTCNAAYYTNGAYTAYYTNMGNMGNAAY---CARCARAAY GARACN---GGNGAYGGNGARACNTTYTCNGGNCAYGTNCCNGTNGARCARYTNGARATH AGYTAYAGYMGNAGYGGNGGNCCNGGNGGNCARAAYGTNAAYAARGTNAAYAGYAARGTN GARGTNMGNTTYCAYATHGAYTCNGCNTCNTGGATHCCNGGNTGGATHAARCCNMGNYTN TCNGARCARGARCARAAYMGNATHACNAARGAYGGNTTYYTNATHATHAARTCNGAYATG ACNMGNAARCARATGYTNAAYCARGCNGAYTGYGTNAAYAARYTNMGNAAYGTNATHTAY CARGCNTCNYTNYTNCCNAARGARCCNACNGARGARGARYTNAARACNAARGARAARMGN ATGATGAARGCNAARGCNAAYATHYTNMGNGARAARMGNMGNMGNTCNCARGARAAYAAR GCNMGNTCN------------TCNACNCARGCNATHAAYCARYTNAARTAYAAYCCNTAY CAYAARTCNTCNYTNGCNTCNGCNTCNGARGAYGGNGGNGTNGCNTTYTGGGAYACNAAY ACNMGNAGYMGNATHCAYGCNTTYAGYGCNAGYCAYCARGCNCCNGCNATHGAYATHGCN TTYTCNCCNGTNAAYGAYCAYYTNATGGTNTCNGTNGGN--------------------- ------------------------------------------------------------ ------------------------------------------------TCNAAYCCNGAR TCNACNGCNGCNATGYTNTAYGAYGTNMGNMGNTCNTTYMGNGAYGTNATGGCNGCNGAY GGNTCNACNTGGCARGGNTGGTGGAAYACNGARTTYAGYCCNACNYTNYTNTCNMGNATG ATGGCNGTNGTNYTNTGYAARGCNAAYYTNYTNGCNGAYYTNMGNACNCARGARAGYTAY GGNGAYGCNCAYTGGTCNATGTGYGARTCNATHYTNGARAARTAYTCNTCNTGYGAYAAR ATGAARGCNGCNGAYCARGTNCCNAARATHCARGARYTNYTNAAYAAYATHTTYAARMGN TCNAARTTYYTNMGNTAYGAYGTNACNAARGAYGTNTTYAAYAARMGNTTYTCNCARGCN ATHACNAAYGTNATHCARTTYCAYGAYACNACNCAYCCNATGAAYAAYTTY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TTYAARAAYATHCCN YTNAAYCCNTAYGARATHGARATHMGNAARYTNCARGAYYTNYTNCARCARACNAARATH CARCARACNATHGAYGAYATHCAYTTYGARYTNCAYGARCCNGARTCNAARYTNYTNAAR GAYGTNGARCAYGAYGARACNGARYTNMGNTCNGARGCNAARGCNGTNAARYTNGARACN GGNGGNAGYYTNTAYAGYAGYACNGARTCNATHAAYAARGTNGCNACNGAYGCNAARGAR ATHCARYTNGARGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNGARGCNGCNATHGTN YTNGGNAGYYTNGCNAARGGNGGNCARGARACNGTNCARAARYTNGTNGAYGCNAARGCN GTNTCNGTNATGYTNCARTCNYTNAAYACNTCNAAYYTNAARTAYTGYGARGCNGTNYTN MGNTGYYTNMGNTCNATHTTYATGCARAAYACNGAYTGYATHGAYGTNYTNTAYGARGAR AAYAGYTTYGGNCCNTCNTAYATHCCNACNYTNYTNTCNATHACNCARCARTCNYTNGTN TGYCARGARTGYGTNACNAAYATHYTNGTNTGYTGYTGYAARACNMGNGAYCAYCARAAY TGYYTNYTNAAYAGYCARGCNYTNCCNATHYTNTCNCCNYTNYTNCARTCNAGY---CAR TAYAARATHCARATGCCNACNYTNMGNTTYTTYGCNAARYTNTGYCAYAARAAYTGYGAR GTNTGYACNGCNGTNGCNAARGARGAYAARYTNGTNGARACNTTYGTNCAYYTNATGGGN MGNGAYAARCCNACNGARATGCARATGGCNGCNGCNGARATGYTNACNAAYYTNCAYMGN TGYGGNGTNATHCCNGCNMGNGAYTTYATHATHAGYMGNAARACNYTNGGNACNYTNGTN MGNATGTGYATGMGNGAYMGNAGYGTNGARGARAAYGTNAARGGNGCNGARATHYTNGCN TAYYTNATHGARATHGARCCNGAYYTNCARYTNACNGCNAGYTAYACNTTYCAYYTNATH GGNGCNYTNGCNAAYTGYYTNCAYTAYCARGAYTCNGAYAARATGTCNTCNAGYGGNAAY AARGAYGTNGAYTGGGGNAGYGARATGMGNMGNGCNGCNTTYYTNGCNTTYGCNTCNATH AGYGCNAAYGAYGARGARATHMGNGARAARGTNATHAARCARGARGGNATGATHGARCAY ATHCARACNTCNYTNTCNAGYAGYAGYGAYGGNGARGTNGCNGCNAGYYTNMGNTGYYTN CARTCNYTNACNMGNTCNGTNCARCARATHMGNACNGTNYTNCAYGAYAAYGCNGTNTGG AARCCNYTNYTNGARAARGTNMGNTCNGGNAAYAARGARATHATG--------------- GTNYTNGCNATGTCNTGYYTNTGYAAYYTNGTNYTNGARTTYTCNCCNAGYAARGARGCN YTNGTNGARAAYCAYGCNGTNGAYGTNYTNTGYGGNYTNTGYCARAGYGARGAYAAYATH GTNMGNYTNAAYGCNGTNTGGGGNATHATGTCNATGTCNTAYTAYGCNTCNGARGAYYTN MGNACNAAYGTNATHAAYAARYTNGGNACNGAYACNYTNGTNMGNMGNATHCARGAYCCN GTNGTNYTNATHMGNGARAARGCNYTNTGYATHGTNMGNAAYYTNYTNGCNGGNAARATG ACNATHGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGTCN ACNTAYATHMGNMGNTAYGCNAARTAYYTNAAYGARAARGCNGTNTCNTAYMGNTCNATG GCNTTYGAYTTYTGYAARGTNAARMGNGGNAARGAYGAYGGNYTNYTNMGNACNATGAAY TCNGARAARYTNYTNAARACNYTNCCNGTNYTNCARCARCARYTNGAYGCNYTNYTNGAR TTYGAYTGYACNCCNAAYGARYTNACNAAYGGNGTNATHACNGCNTGYTTYATGYTNYTN TTYAARGAYYTNATHMGNYTNTTYGCNTGYTAYAAYGAYGGNATHATHAAYYTNYTNGAR AARTAYTTYGAYATGAAYAARAARCARTGYAARGAYGCNYTNGAYYTNTAYAARMGNTTY YTNGTNMGNATGGAYAARGTNTCNGARTTYYTNAARGTNGCNGARAAYATGGGNATHGAY AARGGNGAYATHCCNGAYYTNGCNAARGCNCCNGCNAGYYTNYTNGAYGCNYTNGARCAR CAYYTNGCNTCNYTNGARGGNAARAARTCN---GCNACNACNCCNACNGGNTCNAGYAAR CCNTCNGGNTTYACNACNGCNYTNAAYAAYATGTCNAGYAAYACNTTYACNGTNAGYGAR GCNGARAARAARMGNATHYTNGARGARGARAAYCARCARYTNCARMGNCAYAAR------ ---------GARCARAARYTNAARGAYAAYACNTCNCCNCARAARGCNGGNGCNCCNACN GCNAAYAAYCCNTTYTCNAGYCCNTCNTCNGGNCARCCNCARCARCARCARGAYYTNTTY GGNTCNCCNGTNAAYAAYACN---------GCNAARGCNAGYGAYGAYYTNYTNAGYYTN ACNTCNAAYCCNTTYGCNAGYAAYGTNCARGAYGTNATGGCNACNGCNTAYCARCCNCCN GCNAAYAGYGCNCCNAAYAAYCCNTTYGGNACNCCNGCNTTYCARACNAAYGGNGTNGGN GCNGCN------------AAYTTYGAYGCNGAYTTYGCNAAYGCNTTY---AAYACNGGN ACNAAYGCNCARGGN--------------------------------------------- TTYGAYGCNTTYGGNGAYGTNATGGCNCCNATGAAYAARTCNCCNTCNCAYCARGCNCAY AAYAGYCARGGNGGNAARCCNATGGGNGGNGAYYTNGAYTCNTCNYTNGCNTCNYTNGCN TCNAAYYTNAAYGTNAGYGGNGGNACNGGNCARYTNAARAARGAYCAYCARTGGCARCCN AARGGNGARAAYMGNATGACNGGNGGNAAYCARTTYCARMGNCARCCNATHGCNGCNTCN ACNACNAAYCCNGCNCCNCCNCARTGGGGNCARCCNGGNTTYCARCARCARCCNAAYATG ATGACNGGNGTNCCNGGNGGNCCNATGATGTAYGGNCAR---------CARCARATGGGN ATGCCNATGGGNCARCCN------ATGATGGGNATGACNCCNCARCCNATGGGNATGCCN GGNATGATGGGNATGGGNCARCARCCNATGATGTAYGGNGCNGGNTTYGGNCARCCNGCN GCNCCNCARCARGCNCCNGCNTCNCARACNAARATHAAYGAYCCNTTYGGNGCNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGGCNGGNMGNCCNAARTCNGGNATHACNGCNGAYACNGAYGTN AAYYTNGAYTTYYTNACNAARGARGARAARGAYGCNYTNYTNTCNAARAARATGGAYATG ATHMGNCARMGNAAYAARATGATHAGYGARMGNCAYGARYTNATHGARGCNGAYMGNMGN AARGCNGARGARTCNGGNAAYGCNGTNAARGCNATGGAYAGYAARACNYTNCCNGCNGAR GGNGCNCCNAAY---AARCCNMGNGGNMGNGGNMGNGGNCARCCNTCN------------ CAYMGNGAYGGNAAYMGNATHGGNMGNGAYMGNCCNAARTCNCAYGGNGAYACNTCNTCN TAYGARCCNATHGTNGAYGTNAGYGAYTTYACNGTNCAYMGNACNGTNACNGAYAGYMGN AAYMGNGGNGGNGGNGGNCARCARCARCARCAYCARCAYCAYCAYTAYCARGAYMGNGAR GGNCCNACNTCNACNCCNAARAAYMGNMGNAARCCNCAYCARAARGAYGARGCNGGNTTY CARCARCAYTCNACNGTNTCNCCNCCNGCNATGGCNTTYGAYTAYGARCCNATHGTNGAY YTNAAYGAYYTNGAYCAYMGNTTYGGNGTNMGNGGNTCNTCNTCNTCNTCNTCNTCNAAR CARACNAARCAYACNGAYGGNNNNNNNNNNNNNNNNCAYNNNNNNNNNAAYNNNMGNNNN NNNNNNNNNNNNNNNNNNNNNAARMGNTCNAAYMGNMGNTCNAARCCN---TAYGAYGGN MGNYTNAARTCNGAYNNNAAYCCNCCNCCNGAYCCNACNTTYAAYCCNYTNTCNGAYTGG MGNMGN------------GARMGNGGNGGNGAR------------AARAARGARGGNGAY CAYAARMGNCAYCCNMGNAAYTAYGGNGGNGGNGCNGAYYTNTCNAARGTNAARGAYAGY ATGAARACNATGMGNGARMGNGARAARGARMGNCCNGCNACNTCNMGNAAYYTNGARATG GTNATGACNGGNMGNGARMGNAARAAYCAYGARCARTGGAARCARGAYMGNGAYMGNTAY GAYAAYGARMGNATHCARMGNCARATGGGNGAYGCNGGNTCNTGGAARMGNGARTGGGAY CAYGAYAARATG------GAYTAYGARGAYCAR------CAYCAYGCNMGNGTNGARCCN GGNAARMGNCCN------------------------------------------------ ------------------------------GCNGGNMGNATHGGNAGYGGNMGNTTYGAY MGNGGNGAYAGYMGNGARGAYMGNCCNAARGCNGTNGTNMGN---------------GAY GGNGGNCARTCNCARCARGTNCARTCNCARCARGGNCAYCAYCAY---CAYCAYCCNCAR CARCARCAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CARTCNGGNMGNAARGTNTCNGTNAAYMGNCCN GCNAARGARCAYACNTTYYTNACNGAYGTNGCNAAYGTNMGNACNATGGARCAYGGNYTN YTNACNYTNYTNAAYGAYTTYCAYTCNGGNAARYTNCARGCNTTYGGNAGYAAYGCNACN TTYAAYAARATGGAYGCNATHMGNATHCARCARGARCARYTNGCNAARCARCAYTTYGAR YTNGAYYTNYTNCCNMGNTCNGCNTCNAGYMGNYTNAAYGCNGARGARTCNMGNAARGAR AAYAGYGARAARATGGAYAARYTNATHGARCAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNAARGAYCARTGYCAR ACNAGYYTNMGNGAYAARTAYYTNAARATHYTNGAYGAYACNTGYTAYTAYTTYAAYYTN AARTCNAARATGGARTTYTCNGCNGCNCARGARGARTGYGARAGYYTNTCNGGNMGNYTN GCNYTNATHAARACNMGNAARATHTCNAARTAYYTNTGGAARCARYTNAARTCNAARTCN CARGGNGTNTTYTGGATHGGNYTNMGNTAYGTNGAYATGGARGGNGCNTTYGTNTGGATH GAYGGNTCNATGATHGAYGCNAAYGGNCCNMGNCCNGARCCNGTNTAYYTNMGNMGNGAR AARCARCARCCNCCNACNYTNACNGCNTCNAARCAYCCNCAYGGNGCNAGYCCNACNAAY GGNAGYCAYCCNCAYACNGGNCARGCNMGNCCNYTNTAYTAYGGNAAYGAYAAYAGYAGY GTNAAYMGNCARTCNMGNACNCARACNATHMGNCCNGAYCCNATHCCNGGNCARCCNTAY GCNGGNGCNCCNGCNCARMGNGTNGGNAGYGCNCCNYTNMGNAARATGGCN---AAYCAR GGNACNYTN---------MGNACNAAYGTNGCNAAYMGNTCNACNYTNGAYGCNGARACN GGNYTNGARCARGTNCARTCN--------------------------------------- CARCAYCAYCCNAAYTTYYTNCCN------------------CCNATGCCNMGNCCNCCN CARGCNACNGTNGGNGAYGAYTCNATGYTNGARCARAGYMGNCARATGACNTCNGTNCAR GAYYTNGARMGNCARTTYCARGGNATGCAYATGCCNTCNGCNCCNGGNMGNCCNGAYATH GGNTCNCARTCNAARAARATHTGGGARGAYGAYACNAAYAARCCNGGNGAYCAYAGYCAY TCNGGNATGTTYCAYCAYGGNTGGACNACNMGNGAYGAYACNTGGATGACNGGNGGNGCN AARTCNAGYAAYCARATHGGNGTNAAYATGGTNGARTAYGTNYTNGGNGGNGGNTCNCCN AAYAARATGGAYCCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGAGYACN TCNGTNAGYACNATGMGNGCNGGNGCNAAYAARYTNCCNGGNCCNAAYGAYAARACNACN AAR---------------AGYCCNCARTCNGCNACNACNGTNAARACNGAYGTNCAYCCN AARAARATGCARCCNACNCARGARCARYTNMGNYTNGCNCARATGATGAGYATHAAYCAY AAYGAYGCNGAYCCNAAYACNGTNAARCARYTNATGGAYATGACNGGNAARAGYGARGAY GTNGTNGTNATHGCNYTNCAYGAYGCNGGNAAYGAYGCNGAYMGNGCNGTNATGACNYTN YTNGARGGNGGNGARGARCARGAYGARTGGMGNGARTGYGGN------AARAARAARAAR AARAGYACNCARAARGAYAAYACNAAYAAY------GARGAYCAYTCNGAYGTNMGNAAY MGNGAYMGNGGNGAY------------------------------CARGAYATHCCNCCN MGNMGNGGNMGNMGNAAYGGNGTNCCNCCNCCNMGNYTNGCNMGNGGNMGNGGNMGNGAR MGNGGNAAYTTYGGNGAYMGNGAYAAYCARMGNAAYAAYACNTCNTCNGARGAYTGGGAY AAYGAYAARGARGAY------------------MGNGGNTCNMGNGGNGAYMGNGGNGAY MGNGGNMGNTTYMGNGGNMGNGGNGGNTTYAGYAGYMGNMGNCCNGTNGGNGCNYTNAAY AGYAGYMGNGGNGGNMGNTTYAGYAAY------GAYMGNGARAAYMGNGGNTTYACNMGN CCNMGNMGNTTYGARAARATGAAYAAYTCNCARCCNYTNGAYGGNCCNGARCCNGARATH GAYACNTGGACNAAYGARACNGCNGARACNAAR---ACNACNAARGAYACNGAYTGGAAY AGYTGGAAYGAYTCNTGGGTNAAYGARGARGAYCARTGGACNGGNACNYTNGARGARACN AARGTNTTYACNCCNTCNCAYGTNAARACNCCNGARGCNGAYCCNGTNAGYAAYGARCCN CCNAGYTCNYTNGGNCARMGNYTNGAYGTNGGNAGYYTNTTYGARAGYGCNAARTTYACN AARGCNCCNGAYTAYAGYAARCCNAGYGGNGAYTCNTAYATHAAYCARTTYAAYCARGCN GCNACNGARTCNATHAARAAYACNATHGGNATHGGNAAYACNTCNMGNCCNCARATHCCN YTNTCN---------------CCNCCNGAYACNTCNGGNTCNYTNGGNYTNTCNAAYYTN GGNCARAARGCNGCNCARTCNCAYGGNAGYTCNGTNYTNCCNTCNYTN------CARCAR TCNGCNCARCARAAYTCNYTNCCNCAYGCNATGGCNCARYTNTCNCARATHTCNCARCCN GCNTCNCARTCNACNACNATGTCNCARATGGGNATGGGNTCNCCN--------------- ------------------------CCNGGN---------------CARGCNACNGCNAAY CARGCN---CCNCARCARTCNMGNATHCCNGCNGTNGTNCARCARCARCARCARAGYYTN CCNCARTCNAGYATG------------------AAYAAYATGCCNCARMGNCCNAARACN CARMGNTCNAARYTNCCNCCNCCNTCNAARATHCCNTCNACNGCNGTNGARATGCCNGGN CAYATHCCNMGNAAYCCNCARYTNGAYGTNCARTTYGGNYTNGAYTTYGGNTCNGARACN TCNGTNCARTTYGGNTTYGGNGGNAGYGGNGAYAAYACNGCNGTNACNAGYTCNTAYTCN ACNACNACNAAYGGN---ACNACNGTNATGTCNAAYCAYYTNAAYCARAGYCAYATGACN CARTCNGCNGGNGAYGGNAAYTCNGTNTCNCCNATHATGCCNTCNCCNTCNGCNGGNTCN GCNAAYGTNCCNACNGGNATHGARTCNCARGGNCCNAAYMGN---ACNGGNGTNTTYCAY AAYTCNATGTAYTCNTCNTCNCARCARAARAAYGARAGYCARTCNYTNGARYTNGAYCAR AAYAARGTNAAYGAYTCNATHCCNTTYYTNTCNTCNCARYTNGARMGNAARTCNAGYCCN ATGGCNTCN---CARMGNCCNGGNCARACNAAYCARAAYYTNACNTCNGGNCCNATGACN TCNAGYAARAGYGAYTCNACNAGYGCNGTNGCNAAYAAYAGYTTYTCNGCNGCNAAYGGN TAY---CCNACNTCNTAYCARAGYCAYCCNAARGGNTCNTCNATHTCN------CAYACN GCNAGYTCNCARCCNTCNCARACNTCNTCNTTYCAYGGNCARTAYCCNGTNAAYCARTCN CCNTTYCCNTCNACNGGNCARACNCARTTYCCNGCNCCNCCNAAYGCNACNGCNTTY--- CCNTCNGCNCARCCNTCNCARTAYAAYACNTCNAAYACN------TCNCARAAYCARTTY TCNTCNGGNCARAAYCARTAYTCNGTNGGNACNTCNACNYTNAAYCAY------CARAAY AAYCARTTYCCNTCNACNGGNCARAAYAAYTAYGGNAGYGGNTCNTCNTCNCARTAYTCN GGNTAYCARAAYAAYAGYTCNTTYCCNCCNCAYCCNCARTCNCARACNAAYTTYCCNTCN AGYCARAAYGGNGGNACNGGNGCNGTNYTNTAYCCNACNTCNACNCARTCNAAYGTNTCN GCNTAYACNACNCARTCNAGYTCNTAYCARTCNCCNTCNGCNGGNTCNTAYCAYTCNTCN MGNGAYGGNTCNACNAAYATGACNGTNAGYACNCARTCNAGYAGYGGNATGGCNTTYCCN AGYCARCCNCARAAYTCNAAYYTNAARCCNGCNACNACNCARAAYAAYCCNAGYTAYAAY TCNCARAGYTAY---ACNACNCCNACNCCNYTNCARCCNTCNTCNYTNGCNAAYAARYTN GGNGARAGYYTNTCNAARATHTCNATGAARGAY---ACNTCNGTNYTNGAYAAYCAYCAR TCNTCNCARTAYGARCAYACNCCNTCNCCNGCNAGYGTNCCNACNAGYGTNAGYYTNCCN TCNGCNTCNAGYTCNGCNTCNATGTCNACNGGNTCNAGYGCNATHTCNTCNACNTCNACN GTNACNTCNGCNTCNCCNGCNTCNMGNGTNGCNTCNATGCCNTCNACNTCNGGNAARGCN CCNCCNAAYYTNCCNCCNGGNGTNCCNYTNATGGGNCARTAYATHATGGGNCARAGYACN ATHCCNCCNTTYTAYAGYGTNCARCCNCCNYTNTAYGGNTAYGARGAYGTNCARYTNYTN CARCARMGNATGCCNATGCCNAGYGGNAGYTTYTAYGAYGTNGGNGCNTTYCCNGCNGCN CCNGCNGGNTCNACNYTNCCNACNGGNMGNGAYCCNCARCCNCCNATHCCNAAYGTNCCN TTYTCNGGNACNTCNGAYACNAARYTNACNMGNGTNGAYGCNCARAGYCCNAAYGCNTCN AGYCARCCNCARAGYGCNCAYTCNGCNGCNCARCARCCNYTNTTYAAYTTYCAYTAYGGN TAYTAYTAYCCNTCNATGTTYCCNGGNGCNGCNGGNYTNCARTAYCCNACNACNGTNTAY CCNATHCCNCCNGTNACNAAYGCNGCNGCNCAYCARGGNACNACNGCNACNACNCARTTY CARAARACNTAYCCNTCNCAYGTNTAYACNACNAARGGN--------------------- ------------------------------------------------------------ ---------------TCNGGNACNAGYGARATHACNCCNAAYGCNTAYAGYAARTCNCAY GGNCARGCNGGNTTYGAYAARCARGGNTAYCAYGGNGGNACNCCNCCNCCNTTYAAYYTN CCNYTNGCNTCNGCNACNCARACNGGNCCNATGGGNGCNCCNACNACNCCNTAYGGNGCN CCNTTYYTNCCNGTNATGGCNGCNCAYCARCCNCAYTCNCARATGATGCAYCAYCCNATH CARCARGAYAAYACNACNACNAAYTCNMGNGGNYTNAAYCCNGCNGGNGGNCARGGNAAR TCNGGNGCNGCNAARTCNTTYGGNGGN---CCNCCNTAYTGGAAYAAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGGNATHYTNGAY ATGYTNAAYCCNGCNYTNGTNYTNAARYTNMGNYTNATHGTNTAYGGNGTNYTNATHTTY TTYTCNTTYTTYATHTTYAGYGGNATGGAY------------------------TCNTTY TGYCCNYTNTAYYTNGAYYTNAAYGGNGGNYTNGAYAARGGNCCN---GARTCNAAYTGY GGNTAYCCNATGGCNATHTCNATHATGTAYCARYTNYTNTAYYTNYTNTTYMGNATHGGN ACNYTNGTNYTNGTNYTNYTNGGNAARTTYACNGCNGAYATGGTNYTNTTYTCNGAYYTN GCNGARYTNGTNTAYGTNATHGTNGAYYTNTCNGCNTTYTTYYTNATHTTYATHGCNGCN TGYATHYTNTCNGCNGGNACNAAYTCNACNTGYGAYAAYTAYAARTGYGAYTCNGAYGTN TCN---------ATHTCNGCNTCNAARGCNGCNCARGCNGGNGCNTGGATHAGYACNTTY YTNTGGYTNTTYATHGGNATHTGYGGNTTYATHACNYTNTGGMGNGCNGGNAARATHCCN TTYYTNCCNGGNGGNGGNGCNGCNAARTCNGAYCCNAGYACNACNGGNCCNGAY---CCN GGNCARCCNCARGARACNCCNCCNTAYAAYCCNGAYGARGCNCCNAARTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CCNCARGCNGCNAARGAYGARGARCAYATH GCNAAYGCNGTNAAYCARATHYTNGCNCARGCNGTNCARCARCARMGNGARYTNACNYTN GCNGCNCARAAYGCNCCNCCNCCNCCNCCNAARAGYMGNAAYAARAARATGGAYTCNAAR TTYAARAARMGNATHCARCAYMGNYTNTAYCAY--------------------------- GCNTGYACNAAYGARTGYGAYAGYTCNTCNYTNCCNYTNACNGARACNTGYATGGARTAY TTYCARGAYAGYTTYCCNGGNTCNGARGGNYTNGGNMGNYTNGAYATGCCNATGGCNGCN ACNATHACNAARMGNAAYCARGTNTCNCCNTGYTCNGTNGTNYTNTCNATGATGTAYGCN AARMGNYTNMGNCARCARAAYAARCARTAYYTNCAYTCNATGTCNTCNACNGAYGTNTTY TTYATHTCNATGATGATGGCNAGYAARTAYYTNTAYGAYGARGGNGTNGAYGARGARGTN TAYAAYGAYGARTGGGCNGCNAGYGTNGGNCAYGARACNGAYGAYGTNAAYCARATGGAR ATGGAYTTYYTNAARGARATGGAYTGGCAYYTNTTYGCNACNCAYGARGAYTTYGAYAAR GCNYTNACNGCNGTNGARMGNMGNYTNGCNYTNACNGARGGNGTNAARMGNGGNTGGTTY ACNTAYACNGARATGGCNGTNYTNYTNGAYTGGGAYCCNGTNTGGAAYYTNTGGAAYCAR GTNGGNGTNGAYTGYACNAARATGGTNTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNTGYTGYCCNMGNTCNTGGAAYTAYCARTGYMGNAGYACNAAYACNMGNYTNCCN TGYTTYMGNCARTTYTAYGGNAGYACNATGGARTGGTGYTGYCCNATHTGGCCNTCN--- ---GTNTAYATHMGNMGNTGYGCNTGYAGYCARTGYGCNGTNYTNACNTCNACNTGYGCN AAYGARGGNMGNTGYMGNAGYMGNTAYACNMGNMGNAGYTTYYTNGCNGTNTGY---TAY MGNAAYCAYCARTGGGGNTAYYTNMGNTAYYTNAAYMGNTAYYTNCCNTCNAGYTGYTAY TGYMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGTNTGYGTN CCNTGYTTYYTNATHCCNGTNATHYTNTGGGTNTTYCAYAARTTYATHMGNCCNTGGYTN TCNAARATHTGGGGNAAYTCNGARAAYTAYGTNACNAGYAAYYTNACNTGYCCNATGCCN CARAARAARAAR------------------------------------------------ ---------------------------------------GGNACNACNGCNCARCARGAY ACNMGNTTYTCNGAYAARAARAARAARYTNATGAARACNATGAARTTYGGNGARAGYYTN GARAARAARGTNGAYATGACNAARGTNAAYGTNGAYAGYYTNAARCCNTGGATHGCNCAR MGNGTNACNGAYYTNYTNGGNATGGARGAYGAYGTNGTNGTNGTNTGYGTNCAR------ ------------CAYCCNGAYGGNAARGARATGCARATHAAYYTNACNGGNTTYYTNAAY GGNAARAAYGCNMGNGTNTTYGTNGCNGARYTNTGGACNCAYYTNTGYAGYGCNCARGAR AAYATHACNGGNATHCCNAAYGARTTYYTNGARCARAARAARAAYGARATHAARCARMGN CARGARGARCARGARMGNYTNCARGARCARYTNAARAARAARGARGARCARATHAARGAR CARYTNTCNMGNGARMGNMGNGARYTNGARAARAARGAYATGAAYAAYYTNTCNCCNGAY MGNACNAARCCNATH---------------------GARACNAAYGGNATHAARCCNYTN ATGGAYGGNGGNGAYGGNGTNGAYACN------------AARACNGAYATHAARCCNGAR CCNAAYCARGARGGNGAYGCNAAYGCNGAYACNGAYGTNAARAARGARGARAAR------ AARGAYMGNTCNCCNGAYMGNMGNMGNGAYAAYMGNGAYMGN------------GAY--- ------------MGNGAYMGNMGNMGNCAYTCNMGNTCNCCNGAYMGNCAYMGN---CCN MGNTCNMGNACNCCNGAYMGN---CAYMGNMGNGAYMGNGAYMGNMGNCCNGAYCAYGGN CAYMGNMGNTAYTCNCCN------------------------------------------ ---CCNMGNMGNMGNTCNMGNTCNCCNMGNMGNMGNTCNCCNCCNCCNAARMGNMGNTCN CCNCCNMGNMGNTCNCCNTCNCCNCCN---------MGNAARMGNTCNCCNAARAARGCN GARGCNTCNAARMGNGAY---------MGNTCNAGYAGYGGNAGYAGYTCNAGYGGNTCN GARGAYGAR------------TCNGGNAARGARGGNTCNTCNCCNGARAARAGYGGNATH CARCARMGNMGNAAYTAYMGNAARCAYGAYGARGARAGYGGNAARGARTCNTCNTCN--- ------GAYTCNTCNGAYGGNGARAAR---------------------GGNMGNAAYAAR MGNMGN------------GAYMGNMGNAAYGCNMGNAGYCCNTCNCCNMGNMGN------ ---MGNMGNTCNCCNCCNCCNTAYMGNMGNCCNAGYCCN--------------------- ------MGNMGNCARAGYCCNCCNMGNMGNMGNMGNAGYCCNTCNCCNMGNMGNMGNTCN CCNGCNMGNYTNTCNCCNMGNMGNMGN---------AGYCCNCCNMGNMGNMGNCARGCN TCNGTNTCNCCNMGNMGNMGNMGNTCNGCNTCNCCNCCNMGNMGN---CCNCCNTCNCCN TTYCARGGNMGNMGNMGNMGNCCNTCNMGNTCNCCNTCNGAYTCNCCNGTNAARMGNMGN MGNCARTCNCCNCCNCCNTCNCCNCCNCCNAARTCNAARAARAARMGNGTNTCNCCNCCN CARTCNGARTCNGARGARAGYTCNAGYTCNGARGARTCNTCNTCNTCNCCN---CCNCCN GCNTCNAARMGNCCN---ACNAARGGNAARGARGARCAR------CCNCCNTCNAARMGN GCNGCNCCNCCNGCNAARCARCCNGCNAARCCNTCNAGYGAYGARAGYTCNTCNTCNGGN TCNGARGAYAGYGAYGARGAYTCNGARTCNGAYCARCCNTCNTCNCCNCCNCCNACNCCN CCNMGNCARMGNCARAARCARTCNTCNCCNCCN---------------TCNTCNAAYCCN TCNAAYAGYTCNMGNACNMGNTCNMGNTCNCCNGCNACNMGNMGNGAYMGNMGNCCNAGY CCNCCNCCNMGNAARMGNGCNTCNCAYTCNMGNTCNCCN---GCNCARMGNMGNGAYAAR CCNAGYTCNCCNTCNMGNMGNMGNAGYTCNMGNTCNCCNCCNGCNMGNTCNCCN------ ------------CCNMGNMGNMGNCARMGNGAYACNGAYCCNTCN---GAYCARGARYTN AAYMGNAARGAYMGNMGNCCNMGNGAYGCNTCNAGYCCNCCN---------AARAARMGN CARGTNMGNTCNCCNTCN------CCNMGNMGNGARMGNGGNAGYAARGARCARMGNGGN MGNMGNTCNCCNCARCARACNCARMGNMGNMGNGARGCNCCNGAYAARCARGAYMGN--- ------------MGNAARGARAARMGNCCNCCNTCNTCNGAYAGYAGYAGYGAYAGYAGY TCNGAYGAYGAYGAYGAYGAYAARGAYTAYAARGAYAARTCNAARGCNTCNCARGCNAAR CCNTCNGCNGARAGY---AGYMGNCCNGGNMGNMGNCCNTCNCCNAGYGCNCCNTCNAAR MGNMGNMGNTCNGCNAGYCCNTCNCCN------------------CCNCCNGCNAARTCN GCN---------------------------------------------MGNMGNGGNGAR GCNAARGAY------GARGARMGNCARMGNAGYGAYAARCCN------------------ ------MGNCAYMGNTCNGTNAGYCCNAAYMGN--------------------------- ------------------CAYGCNATHTCNCCNMGNAAYGGNMGNGGNTCNTCNCCNCCN TCNTCN------AARCCNAARAARGAYAARCCNGTNGARTCNGCNAGYAAYAGYGAYTCN GARGGNTCNGAYTCNGAYAAYGCNTCNAARAARAARAARAARAARAARGAYAARAARCAY AARAARCAYAARAARCAYAARAARCAYAARCAYAARAARGARGTNGGN---------GAR AARGGNGARGAYYTNGARCARMGNYTNMGNGARAARGCNYTNATGTCNATG------CAR MGNAARAARACNCARGARTCNCARGAYCCNGAYGARTCNGGNAGYGGNAGYAGYAGY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNYTNYTNATHTCNTGGTTYATHYTNTGYATHTCNGTNTCN---GCNATHGAY MGNCCNMGNGGNGTNCCNYTNGARAARGCNTCNTTYTAYCARYTNGARACNGGNTTYMGN TGYYTNACNAGYGGNAARGCNATHCCNGCNGAYCAYGTNAAYGAYGAYTAYTGYGAYTGY GARGAYGGNTCNGAYGARCCNGGNACNTCNGCNTGYTCNAAYGGNYTNTTYTAYTGYGAR AGYAARCCNTAYAARGGNCAYTAYATHAARTCNACNMGNGTNAAYGAYGGNATHTGYGAY TGYTGYGAYGGNTCNGAYGARTTYGAYGAYATHATHTCNTGYCCNAAYACNTGYGTNGAR AARTAYGARCARGARMGNGTNCARCARGARGCNYTNMGNGTNCARCARTCNGARGGNTAY AARGTNAARCARGARCAYATGCARCARGGNAARMGNGCNAARGAYGARAARMGNTCNAAR YTNAGYGARYTNGARMGNGARMGNGAYATHYTNACNAARGARAARGARGCNGCNGARGTN GTNAARGARGARGCNGARGARCCNGARAARGCNGCNATHGARGARCAYAARAARGCNTGG GARYTNGTNAARGARGARMGNCARAARGCNGARGAYGCNATHAARGCNGCNTTYGCNTTY TCNACNYTNGAYATGAAYAARGAYGGNACNGTNGAYTAYCCNGARYTNATGAARCAYCAR GARTTYGAYATHGAYTCNGAYGGNTCNGTNAGYGARGAYGARGCNAARGARTAYYTNGAR GAYAAYGARCARGTNGAYGTNACNATHTTYACNGARAARATHTGGCCNAAYATHAARGAR ATHTAYAAR--------------------------------------------------- ---AAYGCNCARGARGARAARCCN---------GARGGNTCNGTNCCN---GAYGARCCN AARGGNGAYNNNNNN---------------------------GARGCNGAYCCNYTNGAY GAYAARAGYCCN---GARGARNNNGANCCNNNNNNNNNNGARNNNNNNAANNNNNNNATH NNNGTNNNNNNNNNNNNNNNNNNNNNNNNNNNNGAYNNNNNNNNNNNNNNNAANNNNNNN GANNNNNNNNNNAGYGANNNNNNNAAYTAYNNNGARNNNGAYNNNNNNNNNNNNGARGAN TTYGCNTTYATGAARGGNCARTGYTAYGARTAYACNGAYMGNGARTAYACNTAYMGNYTN TGYCCNTTYGAYAARAGYACNCARAARAAYAARAAYGGNGGNATHGARACNTCNYTNGGN ACNTGGGGNAARTGGCAYGGNCCNGAYGTNGAYNNNNNNGAYACNATGAARTAYGARAAY GGNCARGGNTGYTGGAAYGGNCCNAGYMGNTCNACNCAYGTNAAYYTNCAYTGYGGNTCN ACNACNACNYTNACNGGNGCNTCNGARCCNAGYMGNTGYGARTAYCARTTYGARTTYACN ACNCCNGCNMGNTGYGARGARCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CARGCNCCNGARATHMGNACN ACNYTNTCNCARGCNAAYMGNTCNTTYMGNGAYAARATHAAYTCNAARGGNTAYACNCAR GARTCNGCNGAYMGNCARTCNCARTGGGARGAYGCNCAYTGGCARCCNGCNTCNMGNACN ATHACNGTNAAYTTYCARAAYTTYGAYGTNAARYTNAARYTNGARTTYCARTCNGGNATH TCNAAYATGYTNACNATHTTYTGYTCNGTNGTNGAYCCNGGNGAYTCNATHTCNTGYAAR AGYMGNATHMGNGARATHCCNYTNGAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ACN ATGGARGARGTNGCNYTNYTNAARCARAAYAARAAYGTNGCNATHACNYTNTTYATHGTN YTNGCNACNTTYGTNATHATGGCNYTNCCNTAYCAYGTNTAYGCNACNTAYGTNTCNATH AARACNGAYAARAARAAYTTYTCNACNTAYATGAAYCCNATHGCNTAYTGYTTYYTNTAY YTNAAYTCNATGTGYAAYCCNATHATHTAYGCNYTNMGNTCNCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNGAYGTNGGNTTYGAYGARMGNGARATH YTNCCNGAYGARGGNCAYYTNGAYGAYGGNYTNTAYAARACNGCNGARGARGARGAYMGN GARGARGCNGGNAGYAAY---CAYMGNGGNGAYGGNATGGARGAYAARGARAARCCNATG GAYATHGAYYTNCCNCCNCCNGTNGTNGGNGAYGGNTTYGGNGAYGGNTTYATGGAYGAY GAYGAYGGNTGYGARGAYGAYAAYGAYAAYTTYGGNGAYGTNGAYCARGAYTTYTTYGGN CARGAYTTYATGGGNACNGGNGGNYTNTTYGARGAYCCNCCNGTNATGCCNGCNGARTCN ACNGCNCCNGARTCNGTNCARCCNCCNTCNTCNCCNAARGARGAYGCNTCNTCNAGYAAR CCNGAYAAYGARGCNGARGAYACNGTNAAYYTNCARGCNACNAAYGCNGGNGTNTCNGCN GTNTCNAGYGTNACNGGNGARCARACNACNYTNGTNCAYAAYGARGARGARGCNTTYGCN YTNGARCCNYTNGAYATHACNACNGTNCCNGGNACNGARMGNAARGGNAARMGNAARMGN AARYTNATHGTNGAYGARCARAARGGNATHCCNAGYGARACNATGAARYTNCARYTNTCN GAYACNTCNGAYATHGTNACNTCNYTNGAYYTNGCNCCNCCNACNAARAARYTNATGYTN TGGAARGARACNGGNGGNGTNGARAARATHTTYGTNYTNCCNGGNMGNCCNATHATHTCN AARATHAGYAARCAYYTNTTYTCNATHAAYYTNGTNTGYAARTCNGTNGCNGAYGAYTAY GARCCNGGNGCNAGYMGNATHGAYYTNGAYATGGCNCCNGARATHGCNMGNGARAAYGAR MGNAAYAGYACNYTNCARGAYACNMGNYTNTCNGARATGTCNACNATHGTNGARGARCCN TCNTCNMGNTCNTCNMGNTCNTCNMGNCAYCARTCNATHGTNGAYACNTCNMGNMGNTCN GARCCNTCNGTNACNGCNGAYCARTCNYTNTTYGAYCARATHCCNGAYACNATHCARCCN GTNGAYATHCCNACNGAYCCNAAYAGYATGGTNCCNACNATHAAYTCNATGYTNGAYGAR GGNCCNCCNTCNGTNGCNCCNTTYTCNGTNCCNCCNCCNCCNTGYGTNACNTTYGAYCCN GARCARGAYCARGAYAAYGAYCARATGCCNGARGAYGCNGARCARGARGARAARMGNTGG AGYAARMGNACNCARGTNATGCARGAYYTNTTYGAYMGNGGNTTYAAYGAYCARGAYACN YTNAGYTTYAARGAYATGGCNMGNAAYYTNCAYMGNAARCARGCNGCNTCNMGNTTYTAY ACNYTNYTNGTNYTNAARAARCAYCARGCNATHTGYACNGARCARCCNGARTCNTTYGGN GAYATHTAYATHTCNMGNGGNCCNCARTTYGGNATHGCNTGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CARGTNATGYTNYTNGTN GCNAGYGARACNGGNCAYGTNTAYACNTTYGCNACNMGNAARYTNCARCCNATGATHACN AGYGARAGYGGNAARGCNYTNATHCARACNTGYYTNAAYTCNCCNGAYCCNCCNCCNGGN TCN---TCNGCNACNAAYACNYTNGARCARMGNATGAAYCCNTCNGGNTTYGARGARACN GARYTNTCNTGYGTNGTNCCNGARGAYGARCARAARGTNGGNACNACNAGYAGYGGNAAR CCNGTNTTYCCNACNGGNACNCAYGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTNYTNTCNCARYTNGTNGAY GTNAGYAAYYTNGARACNGCNAARTGGATHTTYCCNGAYGGNACNCCNGARCAYGTNGAY TGGYTNTCNTCNTAYAARGTNYTNACNCAYAARCCNACNGAYGCNMGNGTNAGYCCNGTN AAYGCNAAYYTNGAYTAYGARAGYATHYTNTGYATGCCNAARGARACNAARGAYGGNAGY YTNCCNCCNYTNATHGTNTTYTCNCAYGGNGGNCCNCAYGTNGCNTTYGAYTCNTCNTTY AAYGTNYTNACNAAYTTYTAYTGYYTNTGYGGNTAYGCNGTNGTNATGGTNAAYTAYMGN GGNTCNTGGGGNTTYGGNCARGAYGGNATHGARTCNGTNYTNGGNGCNGTNGGNGAYGTN GAYGTNAARGAYGTNGARGGNGCNATGCARGCNGTNATHACNACNGGNYTNGTNGAYAGY AGYMGNGTNTTYYTNGCNGGNGGNTCNCAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CCNGAYGCNGGNTGGCCNGAY TGYTTYAAYTCNGGNGTNTTYGTNTTYAARCCNTCNGARCARACNTAYGTNAGYYTNYTN CARYTNGCNGTNACNTCNGGNTCNTTYGAYGGNGGNGAYCARGGNYTNYTNAAYYTNTAY TTYAAYACNTGGGCNACNGARGAYATHGGNAARCAYYTNCCNTTYACNTAYAAYGTNGTN TCNCARGCNTTYTAYAGYTAYYTNCCNGCNTTYAARCARTTYCARAGYCARATHAARATH GTNCAYTTYATHGGNGCNGTNAARCCNTGGCAYCAYCCNTAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ACNTCNGCNACNGAYAGYATGAARYTNYTNGCNAARAAYAARACNGAY GAYCARAARACN---------------------GTNGTNGTNGTNGGNAARTCNCCNCCN TCNTCNGGNATHAAYGGNGARGAYAAYCAYGAYCAYGTNCAYTAYAGYTAYCARGGNGAY ATHTAYGCNYTNCCNGAYAAR---AAYACNAGYCCNMGNGAYGAYYTNAAYGARAAYCCN ATHATHTCNMGNATGAARGARATGGTNGTNGARAARTCNMGNACNAAYAGYACNMGNTCN ATGTCNGARGAYYTNMGNAAYAAYACNCCNMGNTCNTTYAAYACNACNACNTCNGCNGGN GAYACNATHAAYGAYGAYGTNAARAAYGGNGTNTCNATHTCNAAYYTNGTNGAYGGNYTN GCNGAYAGYAGYAGYGGNGCNCARTCNGTNCCNATGTCNCCNGTNAARACNMGNGARGCN GAYACNACNTTYGARGARATHAAYAAYGCNGGNAARMGNATHACNGCNTCNGCNTTYGAR TTYYTNAAYACNTAYYTNTCNGAYGAYGARGGNGGNGAYGGNCAR--------------- ---------ATGYTNMGNGAYGCNGARCCNCARGCNYTNCARGTNGAYTTYCARACNACN TCNTTYGGNGAYGARYTNCCNTCNGTNAAYTGYGAYYTNGCNGAYATGAAYATHACNAGY AAYGARTTYGAYCARYTNYTNYTNCARAGYYTNAARGAYATHCCNYTNTCNTTYGAYAGY ---------------------YTNTCNATGGAYTAYGARGGNTGYTCNACNACNAAYYTN AAYGGNTTYACNTCNGTNAAYACNGCNCCNTCNGARYTNACNAAYGTNYTNCCNATHGCN GAYYTNGGNTCNGTNCCNTTYCARACNTCNGCNTCNAGYGARMGNCCNMGNGAYGGNGAY GCNACNCCNCCNTTYTCNGGNGGNAGYACNCCNCARAGYCARTCNMGNGCNCCNTCNCCN GCNTGGAGYGARAGYAGYGGNAAYATGAGYACNAGYAGYGTNTCNAGYYTNTCNMGNAGY ---------YTNACNCARGGNAAYAAYCCNGTNCCNMGNCAYAARMGNCCNTCNCAYMGN MGNGCNGARGTNAARMGNMGNGAYAARATHAARACNACNYTNGAYGARATHAARAGYAGY GTNCCNTCNYTNCARGARAARGGNAARYTNAGYGARTCNGCNATHYTNTTYAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGACNTAYGAY TCNAARCARAARAGYYTNTAYCARTTYTCNTTYTAYTGGGTNGCNYTNGTNYTNTGYGCN YTNCCNYTNTTYGCNACNGTNTTYTGYGTNACNTGGTCNGTNYTNTTYAAYTTYGARGAY TCNACNAARACNCAYTGYMGNGTNMGNAAYTAYYTNCCNTCNGTNAGYGCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ---AGYTCNTCNTCNYTNTGYATHATHGCNAGYGTNYTNGTNYTNATHATHGGNTTYYTN GGNGTNATHCARGARGARYTNACNGGNGGNATHMGNTAYGAYTAYMGNACNGARGTNCAR YTNGARGCNGAYYTNACNCAYMGNMGNYTNATHTGYACNAARAAYCCNGGNCAYGARCAR TTYATHCCNATHAARGARGTNTGYYTNGGNGAYYTNCCNGARTCNYTNAARCAYGAYGAR GTNYTNCARTAYATHAARGARYTNGGNAARYTNGTNGTNMGNATHCARGCNAARCAYACN AGYAARGARMGNCAYAARGAYGAYCCNTAYCAYTCNATGATHGGNMGNCARGTNTAYMGN GGNGCNACNGGNAGYGTNGCNCARGTNAGYGAYCAYYTNCARGTNCARGARATHCCNTGY AARGAYGAYTCNTGYATHATGGGN------CCNGARCAYTGYATGTAYGGNTTYATHGAR ATHMGNACNAAYMGNCAYGTNATH------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TTYGTNAAYACN ATHAGYYTNGAYTTYCAYAGYTGYCCNGGNCCNGTNTAYMGNAARGTNYTNAGYGCNYTN TGGGAYTTYGCNAARATHGTNYTNTTYYTNTTYTTYGTNYTNGTNATHGTNYTNGCNTTY GGNGAYGCNTAYMGNATHTCNTCNACNAAYCARYTNYTNGCNACNGTNGTNGGNGGNTTY GTNCCNTTYTTYTTYAGYCAYTTYTTYACN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AGYACNYTNTTYCARGTNYTNGTNGCNGGNGTNMGNATHGTNCCNAGYTCN TGGGGNATHATHGGNATHATGGAYMGNYTNCAYGAYCAYTTYGAYGAYCCNACNATHCAR ATGTCNTCNTGGAAYTTYGCNAAYMGNYTNCCNGGNCAYTGYMGNGAYAARYTNGCNTCN ATHTCNAARTGYGCNYTNTCNYTNTAYGCNACNGTNGARGARGTNTGYAAYYTNCCNACN MGNGARGARMGNGARAARMGNACNATHAAYYTNTTYAAYGCNAGYTCNACNTTYGAYYTN GARYTNATGGARGGNGTNAARGTNATGATGYTNYTNCARYTNGTNTCNYTNMGNCARMGN ATGYTNGAYGGNGARGAYGTNCCNATHTTYGGNCAYYTNYTNTTYGCNMGNGAYACNTCN GARTCNGTNGCNGAYTTYATHAARAAYCAYYTNAAYTGYYTNGGNGAYTCNGGNGGNYTN GARCARGTNGARATGTGYYTNYTNGGNTAYACNYTNGGNGTNAGYATHAARGTNYTNMGN YTNTCNCARGTNGGNCARGARGAYTTYGARTGYAGYTTYCCNGAYGAYATGCCNTCNAAY ACNCCNCARGTNGTNYTNYTNGCNGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AAYCAYGTNYTNAGYGCN GCNCAYYTNGARTCNMGNGAYGCNATGTTYAGYCAYMGNCAYGCNAGYYTNTTYGARTAY YTNCCNAARGARGARATGGAYAAYCARACNACNATHACNTTYCAYTTYACNAAYACNAGY MGNATGATHCCNAGYGGNATGGARCAYGCNGCNCCNCCNAAYAARCCNGTNTCNGTNYTN YTNTGGTGGTCNGGNACNCARCAYATHTGYCAYTAYTCNYTNYTNAARTCNGCN---AAR GAYATHGARTTYAARCCNGAYATHGTNTGGCCNTGYTCNGAYACNATHACNTGYTCNACN ATHAGYCCNTGYGGNTCNCAYYTNGCNYTNGGNYTNGCNAAYGGNAAYGTNGCNYTNTGG GAYTAYCARATGGGNYTNCCNAARGCNGTNYTNACNGTNTGYGGNAAYGGNGGNGTNAAR GARYTNMGNTTYYTNGAYCCNACNYTNTTYCCNTCNGAYCCNCCNGARTAYCCNCCNTAY CCNGTNTCNTCNGCNACNTTYATHYTNGCNGARTAYTGYGAYGGNACNCARGCNYTNTTY GAYACNTGYGAYGGNAGYCARCARATHCCNMGNGTNATHGCNACNGTNCCNGARAAYGAY GAYGAYGTNCARACNYTNATGAARGTNATHCCNGAYYTNCCNGARYTNATGYTNTTYGTN AARAARAAYGGNTCNATGTAYATHAARGAYGTNGGNACNGGNGCNTCNYTNTGYCARGTN CAYYTNCCNATHCCNCAYACNATHGARACNCCNTGGAAYCCNATHTTYGCNYTNGGNGTN GGNGGNCARGTNYTNTAYYTNAARGGNGARGCNMGNGAYGTNAGYGARGAYGGNGARGTN AGYGAYATHTCNTGYYTNTTYAARTTYAAYYTNMGNGARTTYCCNYTNYTNGAYGARTAY TGGTCNMGNCCNMGNCARAARTCNAAYYTNATHGTNTAYACNACNTAYCARCARMGNYTN GAYTCNYTNATGAARGARMGNYTNGARCARCARGCNATGMGNAARCCNMGNATGCARAAR CAYTGGGGNCARYTNMGNGGNGARYTNGAYATHATHCARAAYGCNMGNGARGTNCCNGTN GAYACNYTNMGNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNACNGCNTAYGCNACNCCNCCNACNYTNYTN CAYMGNGTNGGNYTNGARTCNAGYTCNACNGGNTCNTCNTTYCCNGCNGAYTTYACNAAR CCNGTNCCNYTNGCNGTNATHTCNCCNGGNMGNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AGYGTNGGNGARTAYAARAARGGNMGNMGN---MGNGAYAARTCNCARCARGCNACNGTN GARYTNGTNYTNGAYCCNMGNACNMGNATGATHYTNTAYMGNATGYTNAGYAARGGNACN YTNTCNGARATHAAYGGNTGYATHAGYACNGGNAARGARGCNAAYGTNTAYCAYGCNACN GCNAARGAYGGNTCNGAYAAR------------------GCNATHAARATHTAYAARACN TCNATHYTNATHTTYAARGAYMGNGAYMGNTAYGTNACNGGNGARTTYMGNTTY---MGN CAYGGNTAYTGYAARTCNAAYCCNMGNAARATGGTNMGNGTNTGGGCNGARAARGARATG MGNAAYYTNYTNMGNYTNCAYMGNGCNCARATHCCNTGYCCNGARCCNATHYTNGTNAAR AAYAAYGTNYTNYTNATGGGNTTYATHGGNGARGAYGTNGCNGCNCCNYTNYTNAARGAY GTNGAYATHACNGARTCNAARGCNMGNGARYTNTAYYTNGAYATHYTNYTNATGGTNMGN AARATGTAYCAYCARTGYAARYTNATHCAYGGNGAYYTNAGYGARTTYAAYATGYTNTAY TGYCAYGGNCARGTNTAYTTYATHGAYGTNTCNCARTCNGTNGARCAYGAYCAYCCNAAY TCNATGYTNTTYYTNMGNAARGAYYTNACNAAYATHACNGTNTTYTTYMGNAARAARAAY GTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GARMGNGTNTCNAGY MGNAAYGTNGCNYTNCARGAYGARYTNGAYAARMGNTTYGGNAGYGAYCAYMGNTCNGCN TCNAARGTNYTNGAYCARGTNATGTCNYTNMGNACNAARGARTTYCARAARTCNCARGCN CAYAARGCNAAYAAYATHCAYCAYYTNGCNCARGARMGNCARMGNATHYTNGARGCNMGN AAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARGGNGARGARAGYCARAAYAARGCNGAYGARACN TCNGGNATHYTNAGYGARACNGAYYTNACNGCNATHCARAARATHGTNAAYGAYYTNAGY AARGARGCNTCNCAYACNATHGCNGCNCCNCARGAYAARGCNYTNMGNACNAARATHCAY ATGGCNGTNAARCARMGNTTYTCNCARATGGARACNTCNACNACNGARGAYGARAARGGN AAYAARGTNATHAARGTNGCNTGGMGNAARGGNAARTCNMGNAAYGTNATHMGNGAYGAR TGGCCNCARTCNAARAARTCNTGYMGNTAYGTNMGNTTYGTNYTNTAYAARGARAAYAAR GAYACNATGGAYGCNATHGGNYTNATHGCNAARAAYYTNMGNGTNMGNGARGGNATGTTY CARTAYGCNGGNAGYAARGAYAARMGNGCNAARACNACNCARGARATHACNGCNCAYMGN ATHCAYCCNAARAARYTNGTNAAYYTNAAYAARGTNYTNTGGAAYATGGGNYTNGGNGAY TTYMGNTAYGTNGARCARCCNYTNCARYTNGGNCARYTNTCNGGNAAYMGNTTYACNATH GTNYTNMGNAAYATHCARGCNAGYCAYGARGTNGTNAAYTCNGCNYTNACNTCNYTNAAR GTNACNGGNTTYATHAAYTAYTTYGGNATGCARMGNTTYGGNACNACNGCNGTNCCNACN CAYMGNATHGGNAGYGCNYTNYTNAARGGNGAYTGGGAYMGNGCNATHGAYYTNATHYTN GCNCCNMGNAAYGAYYTNCCNGCNAARGAYAARTTYCARACNAARTGGGCNGARACNAAR GAYCCNTGGGCNACNYTNGCNYTNACNCCNMGNTTYTGYGGNYTNGARMGNAAYATHYTN GARGCNYTNGGNAARAARCARAARCCNTTYAAYGCNYTNGARMGNYTNCCNMGNAAYACN MGNYTNYTNTAYYTNCAYAGYTAYCARTCNYTNGTNTGGAAYAARATGGCNTCNAARMGN YTNACNTGYYTNGGNCAYGGNGTNGTNTCNGGNGAYYTNGTNATGGAYMGNCARCCNCCN GGNGCNAARGGNCAR------GAYTGYCCNCCNCCNGTNGTNGTNACNGARGCNAAYGCN AGYAGYTAYAARYTNATGGAYGTNGTNYTNCCNYTNCCNGGNTTYGAYGTNYTNTAYCCN AAYAAYGCNGTNGGNGAYTGGTAYAARGAYYTNYTNTCNTCNGAYGGNYTNGAYATHGAY AAYATGAARMGNTCNCARAARGAYTAYTCNYTNTCNGGNGCNTAYMGNCAYYTNGTNGTN ATHCCNCARGAYGTNTCNTGGTCNCARCCNACNTAYGAYGAYTAYACNYTNGCNYTNACN MGNAGYGAYYTNGAYYTNATHAARGARGARACNYTN---CAYGAYTGYGGNGARGCNGGN TCNCAYMGNGCNGTNGTNYTNCAYATGTCNYTNCCNTCNTCNTGYTAYGCNACNATGGCN YTNMGNGARGCNATGMGNATHGAYACNTCNTCNTTYCAYCARGCNTCNYTNAAYATGAAY CCNAGYMGNTCNYTNGGNAGYGCNGTNGCNTCNGARGARTGGGAYGAYCAYTGGATHTAY TGGATHGCNCCNATHACNGGNGGNGTNYTNGCNTCNATHGTNTAYAARTTYATHYTNAAY CCNTAYMGNGGNGCNGTNAGYATGGAYGARGCNGTNCARAARATGAAY------------ ------------------------------------------------------------ ------------------------------ATGGCNGAYGARYTNCCNYTNTTYCCNAAR GCNACNTCNATGTAYYTNCAYAGYGGNAAYATGATHAAYTGGAAYMGNYTNAARMGNMGN CCNAAYYTNTCNTCNTCNGAYGARYTNTGYGARGTNATHGCNGAYACNYTNAAYGCNTAY GTNGARGCNGCNGAYAARACNGARYTNCARTAYGTNACNGARGTNTAYAARGTNAARTCN GARAAYGTNGARGTNATHGARGARAGYGARMGNGGNGAYGTNAARATHACNGTNAARGTN TTYATHTGYGAYTCNCARCCNCCNAGYGTNATHGGNGAYGCNGTNACNAARGTNYTNAAY GARYTNGGNACNACNTTYATHGARACNYTNYTNYTNGCNGTNGGNCCNACNGGNGGNGAR GARCAYGAYCCNGARGARGTNGTNAGYYTNTCNACNGTNGARGGNTAYTGGAARGCNATG GARGARYTNGTNGCNAAYGAYAARGTNYTNTCNYTNGGNATHTGYGAYTTYGGNAARGAR GGNYTNGARGCNYTNTAYAAYTGGGCNCARGTNAARCCNTGYGTNGAYCARGTNAAYYTN GARTCNTGYTGYGTNYTNCCNAARGAYYTNACNGARTAYGCNAARTCNATHAAYGTNCAR YTNYTNACNCAYAAYGAYMGNCCNGCNTTYATHACNAARGARYTNYTNCARGARAARATG CARAGYGTNACNACNGARMGNGAYAGYGAYGCNTGGACNCCNGARTGGGTNGTNMGNTAY TCNGGNATHYTNAARTGYMGNGGNATHATHAARACNAARGGNTAYATHTTYCAYGCNGCN MGNGAYAAYAARAARMGNATHYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CARCARGGNYTNATHYTNGARAGYTTYTTYAGYACNGAYACNGAYCAYGGNCCNGCNMGN TTYYTNATHTTYTCNYTNYTNATHCCNTTYATHCAYMGNGARGGNCCNGTNGGNCARAAR GCNMGNGAYGCNYTNYTNYTNATHATGACNYTNAGYAAYMGNCAYCCNCAYATHGGNCAY TAYATHGCNAAYAAYTCNCAYTTYTGYCCNGTNYTNGCNACNGGNYTNAAYGGNYTNTAY TCNTCNYTNCCNMGNMGNATH--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AAYGGNAGYTCNGAYMGNAARAARAARMGNMGNAGYMGN TGGAAYACNGAYAAYGAYGAYAARACNGTNATHCCNGGNATGCCNACNGTNATHCCNGCN AAYYTNTCNGARGCNCARCARMGNCARTAYGTNGTNCARYTNCARATHGARGARATHACN MGNAARYTNMGNACNGGNGARYTNGGNATHCCNTCNAAYCCNGARCARMGNTCNCCNTCN CCNGARCCNATHTAYAAYAAYGARGGNAARMGNYTNAAYACNMGNGARTAYMGNACNMGN AARAARYTNGARGARGARMGNCAYMGNYTNATHCARGARGCNYTNAARYTNAAYACNGAY TTYAARCCNCCNAGYGAYTAYAARCCNCCNATHGTNMGNGTNAAYGAYAARGTNATGATH CCNCARGARGARCAYCCNGARATHAAYTTYGTNGGNYTNYTNATHGGNCCNMGNGGNAAY ACNYTNAARACNYTNGARAARGAYACNGGNGCNAARATHATHATHMGNGGNAARGGNTCN GTNAARGAYGGNAARATHGGNMGNAARGAYGGNCARCCNYTNCCNGGNGARGAYGARCCN YTNCAYGCNTAYGTNACNGCNAAYAAYCCNGARAAYGTNAARAARGCNGTNGARCARATH AARGARATHATHAARCARGGNATHGARGTNCCNGARGGNCARAAYGAYYTNMGNMGNCAR CARYTNMGNGARYTNGCNYTNYTNAAYGGNACNYTNMGNGARAAYGAYGGNYTNCARAAR YTNMGNCARATHGCNGARAGYCARACNATHGTNACNAAYACNATHATHTGYACNGTNTGY GGNGGNACNGGNCAYATHGCNCARGAYTGYAARCARAARMGNCCNGGNGAYACNTTYMGN ATGCARCARATGCARAAYCCNGCNGAYMGNGCNAARATGGAYAGYGARTAYATGTCNYTN ATGGCNGARYTNGGNGARGGNCCNCCNCCNCCNAARTCNGARCARCAR------GCNCCN AAYAAYTTYGGNCARAAYCARTCNCCNTTYAAYMGNCCNYTNYTNTCNAAYCCNCCNCCN AAYCCNATGGCNATGAAYTCNCCNTGGCARATG---CCNGGNAAYMGNCCNCCNATGTCN AAYCCNGTNCCNCCNCCNCCNAAYTCN---GGNCCNCCNYTNYTNAAYMGNCCNGGN--- ---ATGCARTCNACNGCNCCNCARATHAAYCCNATGGGNMGNYTNCCNATGCCNYTNATG TCNAAYCCNGTNCARTCNCCNGCNGGNATGCARCARGGNCCNATGYTNCCNCCNCCNCCN GGNCARCCNCCNCARCARATGGGNAAYCAR------------------------ATGGGN AAYATGCARCARCCNCCNCCNCCNCARCARCARCARCARCARCARCCNYTNMGNCCNTGG CARCAR---------------------------------CCNACNAGYCARGCNCARTCN ATGATGAAYCARGGNGGNATGTCNTCNAAYGCNGGNATGGGNATHCCNCCNCCNCCNCCN TCNATGATGTCNGCNCCNCCNCCNCCNCCNGTNAGYACNCARGGNCAR---GTNCARCAR GCNCCNCCNCCNTGGATGCARCARCARCARCARCARCCNGGNAAYATGGGNYTNCARCAR CARCARCCNCCNCCNCCNCCNCCNCCNTCNACNAAYGCNGCNCCNTGGCARCARCARCAR CARCARCARCARCARGGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNCARYTNCCNACNGARGARGCNCAYGAYTAYCAYGARCCNCCN GTNGCNAARCCNGARCCNAGYCCNCARGARGARYTNGTNATGTCNGCNMGNATHAAYCCN MGNGTNYTNGARAARATHMGNTCNYTNGTNGCNTCNGGNGARACNAARYTNTAYGCNATH MGNAARCARYTNMGNAARTTYGTNGTNMGNGARYTNTAYMGNGGNTCNMGNCARGCNCCN GARMGNCAYGAYYTNACNGTNTTYCCNACNGTNAAYGAYYTNAARAAYCAYATHCAYCAR GCNYTNACNGAYATHCARAAYGGNAAYYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CCNGTNTCN GCNTTYYTNACNTCNCCNATHYTNTCNAARTTYMGNCCNAARMGNTTYGGNTAYYTNMGN AAYAARCARGCNGARGAYTTYGGNTTYGGNCARCARGARTTYTAYATHCCNGAYAARATG AAYCARTAYATHCARACNYTNGAYAARGAYTTYACNAGYGTNATGATHATGGARTTYTTY GAYGARTCNYTNATHYTNYTNMGNCAYAARYTNTGYTGGGGNATGAARGAYATHYTNTAY ATHCCNAARAAYAARAAYAARCAYAARCCNAAYMGNTGGGAYAARGTNGTNCAYAARMGN AAYACNAARGARATGATHGGNGGNTGYTGYGTNTGYTCNGAYGARMGNGGNTGGAGYGAR AAYCCNYTNGTNTAYTGYGAYGGNCAYGGNTGYAAYGTNGCNGTNCAYCARGCNTGYTAY GGNATHGTNCARGTNCCNACNGGNCCNTGGTTYTGYAARAARTGYGARTCNCARGARMGN ATHGCNMGNGTNAARTGYGARYTNTGYCCNCARMGNGAYGGNGCNYTNAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATGGCNGGNGGNMGNMGNATHYTNTCNMGNATHCARTCN AAYGGNCCNTAYTCNTCNGCNGGNAAR---GGNTCNAGYAGYGGNAGYCAYGGNCCNGAY GAYMGNGAYGGNAAYGTNGTNCCNYTNGCNTCNATGGTNGTNYTNCCNAARCAYAGYCAR YTNCCNGAYATHCCNGGNGAYGGNAAYYTNTAYTTYGARTGYATGYTNTTYGTNTTYGGN ATHATHATGATGTGYYTNCARTAYATHAAYYTNTAYAARACNGTNTGGTGGYTNCCNCAR TCNCAYGCNCARTAYGCNYTNAAYTTYTAYYTNATHGAYTTYAAYYTNGCNGCNYTNATH TGYGTNATHYTNGTNATHMGNTTYYTNATHTGYTTYGTNCARGARGTNCAYAGYAAYMGN ATGYTNTAYTGGCCNYTNTTYTGYYTNAARTCNTCNATGGTNGGNTTYTCNGTNATHGTN YTNGTNTAYACNGGNTAYAARGTNATHATGGARCAYGGNGTNGTNACNAGYYTNTTYYTN TGYTAYCCNGCNGTNATHTAYYTNGTNYTNTTYGGNYTNGCNATHAARCCNYTNTAYCAR MGNAAYCARGCNTGGCCNMGNCCNGCNTAYGGNATGGAYMGNCCNGCNGGNCCNATGMGN ATGAARATGAARGAYGAYACNCCNYTNTGYCAYACNTGYACNYTNACNCCNGAYATHGTN MGNGARGARGTNGAYGTNYTNAARAARGAYTTYAAYAGYMGNYTNAARCARATHYTNTTY AAYTCNYTNACNACNTCNTTYTAYGCNACNGGNGTNCCNGTNTGGTTYTCNCARATGAAY ACNYTNTAYTAYGAYTCNTGGTGGATGTGGCARCAYGTNTCNYTNACNTGGYTNAGYGCN YTNYTNATGYTNACNGCNCAYTTYYTNCCNCCNCAYTAYYTNCAYYTNYTNCAYAARAGY GCNMGNCAYYTNGGNMGNTGGCARMGNATGGARGCNMGNCAYGCNCAYGTNCCNTAYAAY GCNTGGTCNGARYTNCARGTNTGGCCNCARGGNGCNYTNGTNAARCAYGTNMGNGGNYTN TTYAARGCNGARGGNATHAAYGTNACNGCNGARCCNGGNAAYAGYYTNCAYAGYMGNTTY TTYYTNYTNTTYCAYCARCCNYTNMGNGTNATGAAYTGGYTNGTNYTNYTNACNTGYYTN GTNATGGCNTAYCARGCNTTYMGNYTNGTNCARAGYTCNGARTGGAGYCAYATHATHTCN YTNGCNYTNYTNATGTTYTGYAAYTTYTAYACNYTNTTYAARYTNATGMGNGAYTGGTTY ATHATGGGNAARATHTAYAARGAYCAYGAYTAYGTNGTNTCNAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TCNGTNTAYATGYTNTCNTGGGTNGARMGNAARGTNGCNTCNGCN YTNTTYGCNACNCCNCCNACNGCNACNYTNGARGARGCNYTNGGNAAYTTYCARAARGCN GARAAYYTNAAYCCNYTNTCNTCNATHTCNAAYCARYTNTAYYTNGCNAARTCNTTYATH GARAARMGNGAYTAYAARGGNGCNGTNGAYTAYATGAARAGYGGNAARGARYTNYTNAGY AARACNGCNGAYGAYMGNATHGCNAARGAYGARATHCARAARYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYATHTAYGAYGAYGCNGTNTCNATG TCNGARAAYYTNTCNGGNTAYGAYTGGTTYCAYGGNAARATHGAYMGNAARGARGGNGAY MGNMGNATHACNTCNATGGGNYTNGTNGGNGCNTTYYTNATHMGNGARAGYMGNGGNAAY GCN---------AAYCCNTAYACNYTNGTNGTNAARACNGARATHGARGTNAARAAYYTN MGNATHMGNCARMGNCCN---GAYYTNCARTAYGCNATHGGNACNACNAARGCNGAYGAR ATHTGYTTYTCNCARGTNTAYGAYYTNGTNGAYCAYCAYMGNGAYAAYTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR ACNGCNGTNATGGARAARGCNGTNYTNCARGTNGARGARAAYYTNGTNACNACNACNCAR MGNGCNGTNCARGCNGARTCNGCNGCNYTNAARYTNAARCARGARGTNAARGGNYTNCAR AAYCARGTNMGNTGYYTNACNGCNGARAAYGARGCNTTYMGNAGYGGNGAYGARGGNYTN GCNGCNATHMGNGARMGNACNAARTAYACNTCNGARCARYTNGAYATHGGNGCNAARTCN GCNGARNNNAAYYTNAARGARYTNYTNCARGGNGTNGARCARATGAARYTNYTNTCNCAR GTNYTNGCNAGYTGGGARAARGTNACNGARGTNAARCCNGAR------------------ ------------------------------------------------------------ ------------------------------------------------------CCNTCN GAYTAYGARCCNGCNGTNGTNYTNGAYAAYCARAAYCCNGAYGTNTAYTGYATHMGNGCN YTNGTNMGNAAYTGYAARAAYGARGAYMGNYTNGCNYTNAARGAYYTNGAYTAYGCNYTN TCNTTYAGYCCNAAYCAYGTNAGYTGYYTNGTNGTNMGNGGNGCNATHACNMGNCCNTGG TCNCCNAARTAYCCNGGNGAYATHCCNMGNCARAAYAARTAYYTNMGNAARGCNGARMGN YTNAAYCCNGAYTCNCARTCNTAYTTYAAYGTNGAYAGYTTYAAYCAYCCNTGYGTNCAR GAYTTYTAYGAYMGNATGYTNTTYACNYTNYTNGTNCCNCAYACNATGACNGARATHAAY YTNACNCCNGAYAARCCNAGYAARAARCARATGGAYTCNAGYCCNGAYCARTCNMGNAGY GARTCNAGYMGNTCNGGNAAYTCNCARATGGGNTCNCCNACNMGNATGGGNTCNCCNACN GARAARGTNGAYCCNTTYMGNTGYGGNACNCCNTCNGTNCAYGAYAAYMGNCAYGCNACN MGNMGNMGNYTNGAYTAYGGNGARGCNGTNMGNAARCAYAAYTCNMGNCCNAARACNGCN ACNGARTAYATGGCNGTNYTNGARAARGARMGNMGNAARMGNATHGARGCNTCNACNMGN GCNCARTCNGCNAGYATHACNGGNCARMGN------TGYCARTCNGCNCAYAARTCNGTN GGNCARTCNTCNTCNACNAAYACNAGYGGNMGNACNACNAARACNMGNGCNACNAARGCN TTYGTNTTYGARACNCCNAAYAAYTAYTCNATHCCNGTNTTYCARCCNATGAAYATHGCN GAYGCNCCNMGNATGTAYTAYMGNCCNTGGMGNGGNGAYAARYTNCCNYTNGGNGARGTN ATHCAYCCNCARCCNTCNCCNGCNTTYTAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AGYMGNYTNAAYMGNAAYYTNGAYCAYAARATHTCNGAYGAR TCNTCNCAYATGCARGAYGTNTGYGTNTCNMGNGCNGTNCARAARGGNATGYTNGCNYTN ATHAARGCNATHATHCAYGGNYTNGGNCARACNATHACNAAYCAYGGNYTNGGNGGNATG GCNTCNGCNTAYATGGTNYTNGARGTNGCNCAYACNCAYTTY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TCNTCNCARTGGCCN CAYAAYCCNTAYGARGTNGCNMGNGCNYTNATHCCNAARGCNCAYMGNYTNTAYTAYAAR TGYTCNGARTTYCAYGARGAYTTYMGNTTYAGYYTNAGYTTYATHGARAAYTGYACNGAR ATHCCNGTNTCNMGNTCNYTNTGYGARAARTCNTGGCARTTYMGNAGYMGNYTNAARMGN AARAAYAAYACNATGMGNATGAGYYTNGGNGAYYTNGARGAYGGNATHTCNTCNATGATH TCNYTNGTNTCNYTNCCNGCNYTNGGNGGNAAYGGNAAYACNGTNGARAARYTNMGNACN YTNACNAGYGAYGARGAYAAYTCNAAYGARGGNTGYTGYGTNATG--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNATGCCNGAYGTNACNAGYATHGGNYTN GGNGGNGGNTCNTAYGTNTCNGARAARAARGAYAGYGAYGGNCAYTGYGTNGCNATHGAR ATHGGNCCNTGYAGYGCNGGNTAYAAYYTNAARAAYGARGCNYTNGTNTAYAAYGARACN GARAAYAAYCARGGNMGNTTYYTNACNACNACNGAYATHGCNGTNGCNTTYGGNYTNTGY GAYYTNGGNTCNMGNGARMGNGTNGCNCAYYTNGAYAARGCNTTYGTNCARAARGCNGTN GAYAARATHCAYGARATGYTNGARAAYATHGTNGAYGAYATHAARYTNMGNCARGARGAY ATGCCNGTNATHATHGTNGGNGGNGGNAGYATHYTNGTNGAYACNAARMGNMGNTTYGAR GGNGCNTCNGARYTNATHATHCCNAARTAYTTYGGNGTNGCNAAYGCNATHGGNGCNGCN YTNAGYAARGTNTCNGCNACNGCNGAYACNGTNGTNAAYYTNATGGCNYTNGTNGAYAAR GARYTNATGGAYGCNMGNGTNCARGARGCNAARGARAGYYTNGARTCNCCNACNGAYMGN GAYATHAARYTNGCNACNGARAGYGCNAARAARCCNTTYATHGARAARGCNMGNGAYCAR GCNATHGARGARGTNATHCARCARGCNAARTCNCARGCNATHAARYTNGGNGCNAARGAR AAYGARGTNGARGTNYTNGARAARTCNGAYTCNGTNYTNGCNTAYATHGARGGNMGN--- YTNAAYATHAARGTNAARGTNGTNGGNGAYATG--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYAARTGGTAYAARATHAARGCNGGNATGTTYYTNACN TCNGTNACNGCNTTYTCNGTNYTNTCNGGNTTYGGNATGACNYTNGGNATGGCNAARAAR CARGAYCCNMGNCAYTTYGCNAARGGNYTNGTNGGNTCNAARGARATHCCNGARAGYGGN GTNGCNYTNGCNACNMGNGCNYTNGGNMGNGCNTCNGTNTAYACNATHACNGGNTAYGGN YTNTTYTGYTTYGGNGTNTGGAARYTNATGGGNGTNCAYAGYTTYGCNGARTTYMGNGAR AARGTNGGNAAYGCNYTNCCNMGNYTNAARMGNACNGARAGYACNGGNMGNAAYGARTTY AGYTCNATHMGNGAYYTNTTYCARTAYYTNATHGAYGARGAYGARAARTCNAARGCNYTN AARGCNGARAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CARGTNTGYACNGARGAYTTYAAYACNGARMGNAARGAYMGNGARCARGCNGTNCARAAR GCNMGNGCNYTNCARGARGAYGTNACNAARYTNACNACNGARATHACNGGNYTNAARMGN CARGTNGARCARYTNAARAAR--------------------------------------- ------------------------TTYGAYMGNATHGAYAGYTGYCARTTYTGYAARAAY GCNGCNGAYAARYTNACNTCNTTYGAYTCNMGNGAYGTNACNMGNATHAARGARTTYYTN GARTCNATHAARYTNGCNTTYATHCAYAAYYTNAAYAARYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GGNATHYTNTGYCAY TCNTGY---------CARTAYTCNAARTGYACNGAYAARTAYGAYGTNGARAARTAYGCN GGN------AAYYTNGGNGAYTGYGGNGAYGAYATGTAYTGYGTNAARTAYAARACNATH GTNTGGATHMGNGAYTCNGGNGARATHAARGGNAAYTCNMGNGARTCNTCNGTNGTNTCN MGNACNTGYGARGCNAARAARGGNMGNAARGARGGNTGYATHGGNTGGCARAAYAAYGGN GGNGTNACNYTNAARTGYTGGTGYGGNACNGAYGGNTGYAAY------------------ ------------------ATGAAYACNMGNGGNGGNYTNCCNGTNAARAAYATHGTNACN GCNATHTTYATHYTNYTNTCNGTNTAYYTNYTNTAYATHTAYAAYGTNGCNCARAAYCAY YTNCAYGAYGCNGARATGACNGGNTCNMGNTAYMGNMGNGARGCNGARGARAARGCNAAY GARATHCARGGNYTNATHTCNGCNAARGAYGAYTTYCARGARMGNTCNGARACNGARAAR MGNGARYTNAAYAAYMGNYTNAARTCNATHAAYCARAARCAYAGYATGYTNCARAGYCAR AAYACNGARGTNGARGCNGAYTTYATGAARYTNAARCARGAYATGGARAAYYTNMGNGCN GARCAYATGCARMGNGARACN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ACNYTNTCNTCNGGNACNTCNACN TCNGARAARAARAARAARCARCCNCARTCNGCNAARGAYATHYTNGAYTCNYTNCARGGN MGNCCNAARAARAGYAARTCNGCNGGNAARAARACNATHCCNCCNYTNATGYTNGAYTCN YTNGGNMGNCCNATGATHCCNATGATGYTNGGNGAYATHACNYTNCAYAGYATGGGNGAR ATHGTNATGGAYMGNACNAGYTTYCAYTGYCCNGARGCNATHTTYCCNGCNGGNTAYTGY ATHACNMGNGTNTTYATHAGYYTNCAYAARGCNGAYTGYAARTGYYTNTAYACNTGYAAR ATHTCNGARGGNGAYAAYGARCCNYTNTTYGARATHGCNCCNGARGAYAGYTCNGAYATH GTNTTYMGNGCNAAYACNCCNGCNGARTGYCAYAGYYTNYTNYTNMGNGCNGTNAAYAAR TCNMGNGGNGCNGAYGTNYTNCCNACNGARACNCAYGGNYTNGAYTTYTTYGGNYTNTCN AAYTCNGTNATHCARAAYYTNATHCARTCNATHCCNGGNGCNMGNAARTGYTCNMGNTAY AARTGGGTNAARTTYGARATHGAYMGNTCNGARACNAAYGARAGYTTYGCNATHGGNAAR AAYGAYCCNACNATHAGYTAYGAYGCNTTYYTNAARCAYYTNGCNGCNYTNACNCARGCN MGNCCNGGN---YTNGCNTCNCARATGGARAARTCNACNAGYYTNMGNTCNYTNYTNACN AAR---------ATGAAYTTYAAYGTNGARYTNGTNYTNACNTCNGGNGGNMGNYTNGGN MGNATHATHCARATHGCNCAYGGNMGNACNGTNACNYTNGAYACNCCNYTNTGYACNYTN TTYACNMGNGGNGGNAGYGTNCCNTAYYTNAGYYTNAGYATGYTNGGNAARGTNAARAGY GTNCCNGARYTNGCNACNATGAGYATGAAYTCNTTYGTNGARCAYGTNGAYAGYYTNMGN GGNAGYGGNAARMGNYTNGCNGARTTYACNTCNATGAARGAYAARYTNGTNTTYTCNTCN YTNCAYGAYGCNAGYYTNCCNYTNTCNTCNGGNAARAAYGAYAARTCNGGNGTNGCNGTN TGGGGNAARGGNGGNAARACNATGYTNGAYCCNGGNYTNTAYATGAARATHCARGARTCN ATHCARCCNGAYTGGYTNATGGCNYTNAGYGAYGGNGAYACNGAYAARGARAGYACNGAR AARMGNGCNGGNAARGCNGTNGAYMGNACNYTNGAYTTYYTNGAYGARATHGTNTCNGCN MGNGARAARTCNGARGTNYTNCARAGYTCNAGYYTNATHGGNGCNGTNGTNGGNGGNTTY AGYGARMGNCAYMGNCARMGNAGYGCNACNGARACNTCNACNMGNCCNGTNCAYGGNTTY YTNYTNGARGGNTTYCARAARGGNCAYAAYAARACNGAYAAYYTNGTNGAYGARTCNYTN CARAARATHYTNACNAARACNATHAGYCAYYTNCCNGARAGYAARCCNMGNYTNATGGAR ACNCCNTGGTCNCCNYTNCARGTNATHCARGCNGTNAARYTNGGNATHGAYGTNTTYTCN AGYGCNTAYCCNCAYACNYTNGCNGARAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYAARGCNGARTCNGGN AARGARGGNGAYATGGAYYTNGCNGAYGAYGAYAGYTCNGGNGTNGGNGAYGARTCNYTN ATHGGNYTNGAYCCNTCNCCNACNAARCCNGGNATGGTNGCN------------------ ------------------------------TAYYTNTAYTTYAARAGYGAR--------- ---------------------ATGTGGMGNAARMGNCARTTYAGYTAYYTNTGYGCNGGN MGNTGYACNGAYMGNGARACNMGNGARTTYYTNGARMGNATHYTNYTNATHGCNGCNGAR TTYTTYYTNCCNCCNTAYCARTTYCARGTNMGNGTNGGNGGNYTNTAYYTNYTNTAYGGN ATHTTYATGACNCARCCNATHGCNCCNAARGTNAARGTNMGNYTNACNGTNAAYCARTGG GARGAYACNATHCARTTYCARCARGARGCNAAYGARCARAAYCAYYTNGAYGTNGTNTAY GTNTTYAAYMGNATGYTNGARGARCAYGCNTTYCARTTYTGYTAYACNCCNACNGARATG AGYGARAAYACNCARAAYGCNGARMGNGARGAYGAYGARATHAAYYTNGCNGAYGAYATG AARGAYGARCARMGNGARATHGAYMGNYTNTTYGAYTAYGARTCNATGGARCARYTNTCN TAYYTNYTNGAYCAYTAYCAYCARATGAARGTNGGNATGTCNAGYTCNAARGCNAGYAAR CCNGAYAARTCNYTNGAYGTNGTNCARGGNTCNATGGTNGARGAYYTNGTNGTNATGYTN CARTCNTTYAARGCNAGYTGYTCNAAYATHTAYAARCAYGGNACN---------GCNAAR GCNCAYGARACNACNCARGARGARGCNGGNCCNTCNGGNAAYAARMGNCARGCNATHAAR TCNAARATHTTYGGNGARGTNGAYGAR--------------------------------- ------------------------------------------------------------ ATGACNACNGTNTGYGGNTGGYTNAAYTTYTTYTGYYTNMGNGARGTNAAYAARAARAAR GCNGTNCARCAYMGNATHCAYCCNAAYMGNCARCAYTAYGAYGCNGTNGTNGTNTGGAAY GGN---AARGARAAYAARAARACNAARGGNAGYATHAGYTTYGAYGTNATHYTNAARCCN GCNGCN------TCN---GAYTCNCCNMGNCCNTCNYTNCCNGTNACNCCNMGNCARAAR GARYTNTCNGARGARAARATHGCNATGAARYTNAARAARGCNGARCARMGNMGNAGYYTN ATHGARCAYGARMGNATGGARCARYTNGCNAARGARMGNCARAARGCNATHGARGTNATH ACNAARGCNCARTCNGARAGYCARGARTTYTCNAARAARACNGARGARAARYTNMGNMGN TCNATGGARGTNMGNMGNGARAAYMGNGARACNCARATHMGNGCNYTNCARGARMGNYTN MGNGARCAYTCNGTNAARGTNCAYGAYGTNCARAARTCNGGNATGGARATGGTNAARGAR TTYGARGCNAARGCNGARATGAARYTNACNCARAARATGGGNACNTAYGARGARAAYMGN AARAGYCARYTNTGYAAYATGYTNTCNAARYTNCARGARCAYGCNAGYCAYATHAAYGAR GTNTGYGTNGCNAGYGARAAYMGNAGYGGNAAYACNGAYGARYTNCARGARCARYTNGTN YTNAARATGGARAAYGCNYTNAARAAYMGNGARGARCARYTNMGNCARATHCARGAYMGN YTNTCNGARCAYGARAAYMGNATHAARGARGTNCARAARAARAARGGNATGGTNTCNTCN GGNGAR---------------------------------------------------TTY YTNMGNAAYCAYYTNGCNAARCAYGGNGGNTTYAARCAYACNTCNACNYTNTCNCCNCAR GAYGGNYTNYTNATHTGYGCNTAYTGYGGNTAYATHGCNCAYAGYAAYATHGAYYTNGTN AAYCAYGTNGCNAGYCAYGCNACNGAYMGNMGNTAYAARTGYACNYTNTGYAAYTGGGAR AGYCAYCAYAARAARNNNGTNTCNAAYCAYATHGARAARMGNCAYAARGGNGAR---ACN GGNAARGTNATGGAYMGNGARAARMGNMGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNYTNTAYTTYYTNTAYACNAAYMGNYTNCCNGARGAYATHTCN YTNAGYMGNYTNGCNAAYATGTGYAARGCNTCNTCNACNTTYGARATHCCNGARYTNAAR TCNACNGCNATHTAYMGNYTNGTNGARGGNATGMGNTGYGAYAAYGTNGTNCCNGTNTTY ATG--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------GAYGARCCNGCN YTNTCNCAYGARCARGGNGARMGNYTNAARYTNYTNATHCAYAARYTNTGYCARAARGAY CCNCAYCARYTNTTYYTNMGNYTNGARTCNCARGTNMGNGARATGGTNATHGARATHAAR ACNGGNYTNYTNCARAARYTNAAYGARAAYGGNGTNAAYAAYCCNGCNYTNGCNYTNGAY TTYACNAGYACNYTNYTNTAYCAYTAYGAYYTNATHACNAARAARGCNCAYYTNYTNGCN CARTAYYTNGGNGGNYTNATHGAYCAYYTNAARCARTTYCARGTNACNTGGGARYTNYTN AAYAARCAYYTNTTYCAYTCNATHGCNCAYAAYGAYCCNGCNATHAGYTGYGTNGGNCCN ACNATHYTNGARCARYTNMGNCARGGNTCNYTNCARTAYGARAARTCNMGNGARGAYCCN TTYTGYAGYGTNMGNAARMGNYTNYTNAARTTYCARGARGARATGTCNGTNGTNGTNGTN GTNTGGMGNGAYTGYCARCARYTNATHGARAAYTAYTGYCARGARGARTTYACNAAYACN CARAARCARGTNTCNCAYMGNGCNAARAGYTTYATHACNCARCARMGNCARYTNYTNAAR AAYCAYYTNATGAARGAYTCNTTYATGGAYGARGARACNATGAARAGYYTNGTNTCNGGN CAYAARTCNTCNAARGARAARGTNYTNTGYCAYMGNTGYAARMGNGARMGNTGYACNTGY GAYGARTGYACNATHACNCAYATGATHACNTGYGGNATHATHAAYACNGARAARGGNACN ACNYTNCCNCCNCCNCCNAGYTCNTTYAAYTTYGCNYTNGAYCAYACNCAYAAYGTNATG GAYATHACNCCNCCNTCNATGTCNAGYACNACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGGGGNTCNATGMGNTCN AARCCNACNGARGCNATGCCNAARCAYTCNYTNTTYGGNACNGCNYTNGARAARGTNGAY MGNGAYGGNYTNGARGAYATHCARGGNMGNTAYATHCCNGARGGNYTNGTNAARGARTCN CCNAAYMGNTAYCCNYTNCCNCCNCAYATHAARGARCARATHCCNGGNMGNGARGGNYTN GARACNTCNMGNAARGARTGGGCNGCNCARMGNGARGCNYTNTCNCARGCNAAYAGYCAR YTNAARAAYAARTCNCARAARGTNTTYGCNTTYAARGCNGAYGGNGCNAARCCNGGNTCN AGYCAYGGNAGYYTNCAYTCNAGYMGNCCNACNTGGYTNTCNGARAARGAYYTNGARCAY TCNAARGAYATHAAYATHYTNGGNYTNGCNCARCAYGGNAGYTAYAAYMGNGAYAARTAY GGNAARAARCCNCARGTNCAYAAYTAYAGYYTNATHGGNGAYATHYTNGCNCCNAARATG GAYTTYAAYTCNCCNMGNGTNGGNATHGARGGNAAYTCNGGNCCNGARGGNACNAARACN AAY---GTNATHTAYGGNCCNGGNMGNCARYTNCCNTAYGAYYTNATGGAYAARTCNCAR AAYTCNAARAARMGNAAYCARCCNCARAGYGTNATHGAYYTNCCNCCNAAYATHMGNCAY CARTTYGGNAGYMGNGTNTGYGAYGCNYTNYTNTCNGAYCARGGNATHGTNACNYTNGCN YTNGARMGNCARAARTCNAARATGGGNCCNGTNMGNCCNTCNAARATHGARAAYGTNAAR GGNYTNCCNGTNAAYYTNGCNAAYACNTAYGAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CCNTTYYTN CARMGNYTNGGNAARMGNMGNTGYYTNCARATHGTNGTNGTNTGYTGGGTNYTNGCNTTY YTNACNAAR---ACNTTYCCNAGYATHAARTTYAAYTGYTAYTCNTGYGAYTTYATHGTN GAYTGYCARTAYAARGGNACNAARCCNCCNTTYGCNAARCARTTYGTNYTNCAYGARGAY TGYTTYGTNATGAARGAYCCNTTYTCNACNACNGGNGGNTTYATHAAYGTNGGNGCNATH TGYTCNYTNTGYAARCARAAYGTNTGYATGTCNAGYGGNTGYAGYYTNTTYTAYACNCAR MGNTTYTGYATHAARTGYGCNTCNGAYAAYATHGCNGAYTTYCCNGCNGARYTNCAYGGN TTYYTNAGYTTYYTNGGNATHATHYTNTTYATGATHATGACNTCNGARGTNGTNTCNCAY GGNGCNMGNTAYTCNTGGGGNTTYGCNYTNTCNTTYTCNGGNGGNTTYAAYACNYTNGAR GTNTGGGTNGCNGAYGCNACNAARATHAGYGAYMGNGARTTYYTNYTNGARAAYAARAAY TAYAARYTNTGYTTYACNTTYACNGGNGGNGGNTCNACNACNAARGAYTAYGCNAARGCN YTNGGNAARTCNATHYTNTTYTAYGAYGCNCARMGNTCNGGNAARYTNCCNGCNAAYAAY CCNATHTCNTGGMGNGGNGAYTCNGCNGTNAAYGAYTGYGTNCCNGGNGGNTGGTAYGAY GCNGGNGAYCAYGTNAARTTYGGNYTNCCNATGGCNTCNTCNACNAAYYTNYTNYTNTGG TCNATHAAYAARTTYAARGAYGGNTAYGTNAARGCNGGNGARYTNGAYATGATGTAYGAY ATGATHAARTGGCCNYTNGAYTAYTTYYTNAARGCNTGGAAYCCNACNAARAARGAYYTN GTNGTNCARGTNGGNGAYGGNAAYAARGAYCAYAGYTTYTGGGGNMGNCCNGARGAYATG AARATGGAYMGNCCNTGYYTNCAYGTNAAYACNGGNACNAARGGNAGYGAYATHGCNGCN GARACNGCNGCNGCNYTNGCNYTNGGNTAYYTNGTNTTYAARGAYAARGAYACNCARTAY GCNACNCARYTNYTNACNGCNTCNGARAGYYTNTAYGCNTTYGCNAARAGYAAYMGNGGN GTNTTYGGNGGNTCNTCNCARTTYTAYGGNTCNAGYGGNGAYAARGAYGARATGTGYGAR GCNAGYGTNTGGYTNTAYAARGCNACNAAYAAYAARCARTAYYTNAAYGAYGCNAARACN TTYGTNGARACNGCNTGGGGNTGGGCNYTNAGYTGGGAYGAYAARAARATHGCNTGYCAR GCNYTNYTNTAYGARACNACNAARGAYGCNAGYTAYAARGAYGCNGTNGTNGGNTTYTTY CARGGNTGGYTNCCNGGN---GGNGTNACNTAYACNCCNTGYGGNYTNGCNTGGMGNGAY AARTGGGGNGCNAAYMGNTAYGCNGGNAAYGCNGCNTTYATGGCNYTNGTNGCNGCNGAR ATGGGNATHAAYACNAARACNTAYMGNACNTGGGCNGTNGARCARATHAAYTAYYTNYTN GGNGAYAAYAAYCAYGAYGGNGGNTGYTTYAGYTAYGARATHGGNTAYGGNAGYAARTAY CCNAARCARCCNCAYCAYMGNGGNGCNTCNTGYAGYCCNCARATHYTNCARGGNGCNYTN GTNGGNGGNCCNGAYGCNAGYGAYAAYTAYMGNGAYGTNMGNACNGAYTAYGTNCARAAY GARGTNGCNACNGAYTAYAAYTCNGGNTTYCARGGNGCNYTNGCNGGNATHGTNCAYYTN GTNGCNACNAAYAAYYTNCCNGTNACNCAYAAYAARTGYCCNTGY---------TTYGAR GAYGARATHAARACNYTNAARGAYTCNTTYCCNAGYCARACNAAYMGNTTYTGGACNACN YTNTCNGCNTCNGCNYTNCAYGTNTTYGARCARCARGAYCCNTGYTAYCCNAGYGTNATH YTNATGGCNTCNCARAAYMGNCAYAARCARYTNAAYACNTGYYTNGCNAARAARATHGCN TCNACNTTYTCNTCNTCNTTYGGNMGNAAYTCNTCNGCNGTNGGNACNGAYGTNGARGAY TTYAARCAYATGAAYGCNGCNGARCARAARYTNTAYYTNGAYAAYACNATGCARAARGCN TTYCARCARGARGGNGGNAARGCNTTYGTNATHAGYAAYGTNCAYTCNYTNTCNCCNAAR GCNGCNYTNYTNYTNCAYGGNTTYTGYGAYGGNGAYAAYGCNCCNTTYAARGAYGTNATG ATHATHYTNACNTTYCARGTNGAYGAYGGNATHACNTTYACNTCNGTN---------AAR GARGTNGARMGNTTYYTNACNGAYATHTGGAGYAAR------------------------ ------------------------------------------------------------ ------------------------------------------------GARYTNGGNAAR YTNGGNATHGAYTCNAAYGAYGAYAGYGCNMGNTAYATHYTNTCNATGGARAGYTCNAGY GAYYTNGARGARTAYATGYTNGARYTNYTNGAYGGNTCNAAYCCNAARGTNMGNTTYTTY YTNCARGARYTNAARGAYMGNGCNAARGGNAARGGNAARGCNGCNCCNTTYCARGTNTAY MGNAARGAYATGGCNTCNGARCCNAARGARGARAARTCNAARAARAARAAYAARCCNGCN TCNAAYAAYACNAARAGYAAYTCNAARGCNTCNAAYCCNAAYCARCARATHGTNAAYGGN AAYGTNTCNGARAARTCNTCNGGNGCNAARCARAAYTCNCCNGTNGGNACNACNCARAAR GCNGGNGARATHGGNGTNGGNGCNAARAARAARCCNAARTAYGTNCCNTTYTAYAGYCAR GARGGNCARGGNAARGCNATGGTNCARYTNGCNGGNMGNCAYMGNTGYGAYTGYCARGCN TCNAARCAYAARYTNATHAAYAAYTGYACNCARTGYGGNMGNATHGTNTGYGAYCARGAR GGNGCNGGNCCNTGYGTNTTYTGYGGNAAYYTNGTNTGYACNCCNGARGARATGGARATH YTNGAYMGNGGNACNAARAARGCNGARAARYTNMGNGARCARYTNATGAARGARGGNTCN AARAAYTCNAARTCNAGYGARGCNGCNCARTCNATHYTNCCNATHGGNTTYAGY---AAY CARTCNAARGARGARAARGARAARGCNYTNAARCAYMGNGAYAARYTNYTNGARTAYGAY MGNACNAGYGTNMGNMGNACNCARGTNATHGAYGAYGARTGYGAYTAYTAYGCNACNGAY GCNAAYMGNTGGYTNAARAAYGARGAYMGNGARAARYTNMGNAARMGNGARGARGARYTN MGNGARTCNMGNCAYGGNTCNMGNMGNAAYMGNAARATHACNTTYGAYATHGCNGGNMGN GAYGTNMGNATHYTNGAYGCNGARGAYGAYTCNGGNAARAAYATGTAYAAYMGNGARGAY GCNGTNATHCARGARGTNCAYTAYGGNAARTCNYTNCCNAAYGGNGCNGGNAAY---GAY YTNGTNAAYCCNYTNYTNGGNTTYGARCCNCCNACNTAYATGGAYACNCARCCNGTNAAR TGGGGNCCNGAYACNTTYAARCCNTCNAAYGAR---CAYTTYAAYCCNCARGTNTCNTCN MGNMGNAAYCARGAYAARGARYTNCARGARATGAGYGAYGARGGNATGTGYYTNAGYATG CAYCARCCNTGGGCNTCNYTNYTNGTNTGYGGNATHAARATGCAYGARGGNMGNACNTGG TAYTCNCCNYTNMGNGGNMGNYTNTGGATHGCNGCNACNGCNAARGARTGYGAYATGGAR GARGTNAGYGAYYTNCARCARTTYTAYAARCAYTTYTAYGGNGAYTTYAARATGAARTTY CCNAARGARTAYCCNACNGGNTGYYTNYTNGGNTGYGTNAGYGTNGAYGARTGYYTNGAY CARGTNCARTAYMGNGARAARTAYCCNGAYGGNGARTCNMGNTCNCCNTAYGTNTTYGTN TGYTCNAAYCCNYTNAAYYTNYTNGTNAARTTYCCNYTNAARGGNAARCAYAARATHTAY AARYTNGARTCNCARATHCAYCARGCNGCNAARAARGGNATHMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CCNCCNTCNTTYACN TTYCCNTCNYTNAARYTNTTYATHYTNATHACNGTNYTNTTYATGTCNGTNTTYCCNGCN GCNGGNCARGTNGGNGTNTGYACNGAYGARTAYCARACNGCNAARCARAGYYTNAAYATH TCNGARTCNGGNGCNCCNGAYTCNCARTCNCAYTGYACNGCNYTNMGNACNTAYAARCAY TGYATHGCNGGNTGYCARGGNTGYCARGGNAAYATHATGTAYTAYAGYATHMGNAAYATH GTNGARMGNCARATGAGYGTNTAYAAYTGYAAYAARACNGGNATHATHGTNAARCCNGCN GARAARAARTGGYTNCCN---GTNCCNGCNGTNTGYCARTAYACNGGNAARAARGTNTAY MGNCAYTGYGGNYTNTTYGGNGAYCCNCAYYTNMGNACNTTYAAYAGYGAYTTYCARACN TGYMGNGTNAARGGNGCNTGGCCNYTNGTNAAYAAYGAYCAYYTNATHGTNCARGTNACN AAYGAYCCNGTNGARGGNAAYGCNGAYGCNACNGCNACNAGYAARYTNACNGTNATHGTN AARGGNAAYAARYTNTGYACNTCNAARGAYTTYCARACNTAYCARGCNCARACNAAYAAY YTNCCNGGNGCNTTYGARGAYGGNCAYGTNACNTAYGGNCCNTAYMGNAGYYTNGARYTN GTNGARGTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGGCNTCNCCNGTNTAYATGTGGTAYACNAARGARGTNTTYTAYTGGMGN AGYYTNGCNGCNACNYTNTGGTCNGTNATHTGYGTNCCNGTNATGATHTTYYTNATGTCN YTNATHYTNAAYATHTCNYTNACNAGYCCNYTNAAYTGGATHTCNGGNGCNGTNACNGGN ATGYTNACNCCNAAYTTYYTNTGGACNYTNATGGCNTTYACNATHGCNGTNGTNTCNGTN ACNTGGTTYTCNYTNCCNTAYYTNACNGTNAARCARGARATHAGYACNTCNMGNYTNTCN AGYGTNYTNAGYYTNTTYMGNTGGTCNMGNYTNCCNYTNYTNGTNATHTGYYTNYTNAAY GGNTCNYTNTGYGCNTGGAGYGTNACNAGYTTYACNGGNTCN---GCNTTYACNGAYTTY GTNAGYACNCCNGARTAYGARAARACNGTNYTNAAYGARAGYTGYYTNTTYATHGTNGGN TGYGGNATGTTYACNGGNTTYTGYTAYTAYTGYCARTTYTTYGCNMGNCARGARTTYCAY YTNGGNTTYCCNGGNATHCARMGNCARAARGTNTTYCARGTNMGNAGYGARACNAARATH ATGGCNGARMGNATHTCNTGGCAYACNYTNCAYGTNATGAARTAYTAYTAYATHYTNTAY TTYYTNTTYGGNTCNYTNCCNMGNGCNTGGATHTGYACNTCNTTYGGNATHAGYGARGAY ACNGARTCNTCNCCNYTNGAYTCNYTNGTNGGNYTNATGAGYYTNTCNYTNYTNTGGAAY TCNTAYYTNACNTCNTTYGTNATGACNTTYGCNYTNTCNTTYACNYTNGCNYTNACNMGN ATHTAYCAYACNGARCARYTNGARTTYCCNGTNACNAGYYTNATGGARTAYTCNAAYGGN MGNACNYTNCCNGAYGCNYTNGCNTGYTCNTAYTCNCCNYTNYTNCARCAYYTNGCNTTY TAYGAYYTNGCNTGYYTNGGNAARTAYATHTCNCCNMGNATGCARGARYTNYTNAGYYTN AGYCARCCNGGNGGNCAYCCNAARGTNTGGATGGCNGTNAGYCARTCNGCNYTNTCNGCN ATHCARGARYTNACNAAYCARGTNAARGARGARAAYTGGTTYATHATGTCNAARGTNCCN ATHAGYCAYCAYAAYGGNGTNGCNAAYGGNAAYGGNAAYGCNACNCAYATHYTNGAYGGN GARMGNYTNGAYTCNTAYMGNGGNGARGGNAAYCCNGAYGTNGTNCARGCNGTNAARGAR GARCCNGARAARCCNGGNTTYATGGCNCARYTNAGYCAYMGNYTNTCNTCNATHCCNATH YTNTCNCAYYTNGTNACNCARAGYCARGAYTCNAAYAGYMGNMGNYTNTTYGTNTCNTGY CARAARCARATHTGGGCNGTNGARAGYYTNTCNCAYATHGCNGTNMGNGCNTAYACNGAR GAYAARTAYGGNATHGTNCARACNTCNYTNCCNATHATHTTYATGTGYYTNYTNGARYTN CAYGARTCNATHGARAARCAYTTYAARYTNAGYACNTCNCCNMGNMGNTCNAAYGGNTCN GTNCAYTCNTCNACNGAYTGYGTNATHMGNTAYAARYTNCARTCNGTNYTNAARTCNTCN YTNTAYMGNATGGTNAAYACNTAYMGNTCNCAYYTNGARGAYATHAARYTNMGNCCNGAR GARATGAARAARYTNACNCCNTTYATHCAYTAYACNYTNTTYGARGCNATHCCNTAYACN TTYTAYGARCCNGGNACNACNTAYTTYTGGGTNCAYTTYGGNYTNGTNATHYTNGGNTTY GTNYTNGCNGTNGTNACNTGYATHGCNCARTGGMGNAARCCNGCNCCNTAYGGNAARCAY GAYTCNAAYGARGARAAYTGGGGNCCNYTNATHCAYCARMGNYTNTCNCAYTTYATHTCN GAYGCNYTNTCNGGNGTNATHATGTTYTCNYTNGTNTTYTTYYTNTAYAGYMGNGARGAR AGYGAYAARAARGCNYTNAAYTAYGTNTTYTTYGGNYTNTTYYTNGTNCAYACNGTNCAY MGNGGNATHATHCAYCCNYTNATHATGMGNTAYAARAGYGCNAARGTNTCNYTNGGNATH TGYATHGGNGGNGGNYTNCCNAAYGTNYTNTAYCARTGGYTNATHGCNAAYCAYATHGGN GTNGCNAARTAYAAYGAYTCNTAYCCNTAYGAYCCNMGNTTYATHYTNGGNGTNTTYYTN TAYATHGCNGGNTTYATHATHAAYMGNTGGGCNGAYTGGAARYTNMGNTCNYTNMGNGAR YTNGTNGGN------------------AGYAARGGNTAYTAYATHCCNTAYGGNGGNYTN TTYAAYTAYGTNTCNTGYCCNAAYTAYTTYGGNGARYTNGTNCARTGGATHGGNTGGGCN ATHGCNACNTGGTCNYTNTCNGGNTTYGTNTGGGCNTGYTTYGGNGCNGCNACNTTYYTN GCNMGNTCNMGNCAYAAYCAYAARTGGTAYCARGARCAYTTYGAYGARTAYCCNTCNCAR MGNAARGCNYTNATHCCNTTYATHTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CAYMGNATHATHGARAARMGNMGNMGNGAYMGNATGAAYAAYTGY YTNGCNGAYYTNAGYMGNYTNATHCCNGCNAGYTAYCAYAARCARGGNCARGGNMGNATH GARAARACNGARATHATHGARATGGCNATHAARCAYATHAAYATGYTNCARCARMGNGTN GARGARYTNGARAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNGCNMGNGAYATHGGNGAYGGNACNYTNTGGMGN GAYATHCCNGCNAARMGNAARYTNGCNAARGARGTNACNTCNGGNAARCCNGTNAAYTAY CARGTNTCNGTNACNACNGGNGAYGTNMGNTAYGCNGGNACNGAYGCNAAYGTNTAYATH GTNATHCARGGNAARAARGGNACNACNAARAARATGTTYATGGAYGAYACNMGNGAYAAY TTYGARMGNGGNATGACNGARGTNTTYGARYTNAAYGCNYTNGAYGTNGGNCCNGTNACN CARATHMGNATHGGNCAYGAYAAYGCNGGNCCNGGNGCNGGNTGGTAYTGYGARAAYYTN ACNATHAARAARTAYYTNCAYCAYGAYGAYATGGTNGCNTTYYTNAARAAYYTNAARAAR AARMGNAARCCNAARGAYAARAARAARAARMGNYTNTCNGAYAARYTNAARGARMGNCAR ATGAARGGNYTNCAYGARGARGARTCNGAYAARGARGARTCNGAYGARGARGARGARGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGCCNYTNYTNAARATHGARACNAAYYTNCCNMGNGAYCARATHCCN GARAAYTTYYTNAARGARGCNACNGAYYTNYTNTCNTCNGARYTNGCNAARCCNTCNTCN TAYGTNTGYGTNCARGTNTCNCCNGAYCARGTNATGAGYTTYGGNGGNACNACNGARCCN TGYGCNAAYATHACNYTNAAYTGYATHGGNGTNGTNGGNCCNGAYAARAAYMGNCARYTN GCNCCNGTNYTNTCNAARTTYGTNGARAARCARYTNGGNATHAARCARGARMGNTTYTAY ATHAAYATHTTYAGYGGNGTNCAYYTNTCNGAYGARMGNGTNAAYGARATHYTNMGNGTN GCNAARGARTGGTGYYTNTCNAAYGGNGTNGGNATHAARTGYGGNTAYGAYGARCCNGAR TCNTCNAARGTNAGYTAYGCNCCNATHTCNYTNTTYCCNAGYGTNGTNCCNTCNGCNATH ATHAAYACNGCNAARTCNACNATGATHCAYTTYAAYMGNYTNATGCAYAARGTNGCNATG AAYCAYCARTTYYTNGARGAYTCNYTNAARAAYGTNATHCARGTNGAYGARTTYATGYTN AAYYTNTGGAAYATHTAYATGAARGTNAARGARGAYGGNATHAARCARCCNATHATGATG GGNYTNTTYMGNAAYGAYTTYATGATHAAYTGYCARAAYCARGARGARACNAGYGAYAAR TAYGAYGTNGARAAYYTNCARATHAARCARATHGARTTYAAYACNATHGCNTCNAGYTTY GCNGGNYTNACNCARAARATHGGNGAYYTNCAYMGNYTNACNYTNGGNATGTCNGGNAAR AARTTYACNMGNGAYCARACNCCNACNAAYYTNCCNGCNTCNGGNYTNGCNTCNGGNYTN GCNAARGCNTGGGARYTNTAYAAYAAYCCNAARGCNATHATHGTNTTYATHGTNAGYAAY TTYGARMGNAAYGTNYTNGAYCARTGYGCNYTNGARTTYGGNGTNTAYAARMGNAAYCCN CARATHMGNGTNYTNMGNAARACNATHYTNGAYATHGARGARACNGGNAGYYTNGAYGGN GARAGYMGNYTNTTYGTNAAYGGNGAYGARGTNGCNGTNYTNTAYYTNMGNGAYGGNTAY ACNATHGAYAAYTAYCCNTCNCARAARGARTGGGAYGGNMGNYTNAARATGGARYTNTCN MGNGCNATHAARTGYCCNTCNGTNCARTAYCARYTNGCNGGNGCNAARAARATHCARCAR GARYTNGCNMGNCCNGGNGCNYTNGARMGNTTYATHGAYGAYCCNAGYATHGTNAARGAY YTNMGNACNACNTTYGCNGAYCARTAYAGYYTNGAYYTNGGNCCNGARGGNGAYGARGCN GTNGCNYTNGCNYTNTCNTCNCCNGGNAAYTTYGTNYTNAARCCNCARMGNGARGGNGGN GGNAAYAAYYTNTAYGGNGARGAYATHGTNCARTTYYTNACNCARCAYAARGARAGYAAR GARMGNAAYGCNTAYATHYTNATGCARMGNATHTTYCCNYTNCARCAYCARAAYTAYYTN TTYAARGARGGNGTNCCNTTYMGNYTNTCNACNGTNGTNAGYGARYTNGGNATHTAYGGN GTNTAYATHGGNACNGARGAYYTNGARGARGTNGARAAYMGNGARTGYGGNCAYATGATG MGNACNAARATHGCNGGNACNGAYGARGGNGGNATHGTNGCNGGNTTYGCNGTNYTNGAY ACNCCNATGGTNATH------------------AGYATGAARGTNGARTGYCCNGAYACN GARGARACNGGNACNYTNGARMGNTTYGTNAAYGTNATHTCNGCNAGYACNGCNATHGGN CAYGAYAARCARGGNAARGTNCAYATHGTNCARGTNAAYGGNATGACNGAYMGNGCNGGN GTNAAYYTNCAYGARTTYTCNCARYTNYTNATHGARYTNGGNATHATHAAYGCNATHAAY YTNGAYGGNGGNGGNTCNGTNACNTCNGTNATHAAYGGNACNGTNGCNAAYTTYCCNAGY GAYAARTGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGGCNGARAARTAYAARACNYTNYTNAGYCARGTNGCNGTNTAYAGY GCNACNTCNTTYTGYTTYTCNYTNGCNAARGARACNGGNATGTTYAARACNYTNYTNGAY GCNGCNAARCCNYTNACNTCNGARGARATHGCNGGNGARAAYAARATHAARGARMGNTAY GCNMGNGARATGYTNGGNTGYYTNTCNGCNATHGARYTNGCNAARGTNTCNACNAAYGAR GAYGGNGTNAAYGTNTAYTAYYTNGARGARACNGCNAARGARGCNYTNAAYGGNYTNGAY TTYTCNYTNGCNGARATGAAYTTYCCNGTNATHTAYGGNTCNTAYGARGCNGTNAARGAR TGYYTNGGNGCNGAYAARTGYGGNGCNGTNMGNTAYCARCARTCNTTYATHAAYGCNYTN GAYGAYCAYAARATHAARYTNACNGAYGCNACNATHGAYTGYYTNYTNAARAAYGTNCCN GGNYTNAARGARAAYYTNGARAARGGNATHGAYGTNATHGARTTYGGNTGYGGNAAYGCN TAYCAYYTNTCNGTNYTNGCNACNATGTTYCCNAARAGYCARTTYGTNGCNACNGAYGTN AAYCCNGCNTTYYTNGARCCNYTNAARAARMGNTAYAGYCAYATHYTNAAYYTNAARTAY GAYGTNGTNGAYYTNTGYGCNATHCCNGARGCNGTNGARAARAARTAYGAYYTNATGTAY YTNAAYGAYGTNGTNCAYGAYYTNCCNCAYCCNGCNGARTCNYTNAARGGNATHAARMGN ATGATGAARGARACNGAYAGYTAYTGYACNTTYGTNGAYTTYGCNGGNACNGGNAGYCAY ATHCARGAYGTNGGNAAYYTNCAYGCNGCNTTYAARTAYGCNGCNGCNACNYTNYTNTGY ATHCCNGARAGYTAYCARAAYCCNGAYAGYGARGCNCAYGGNGCNGGNATHGGNAARGAY ACNATGATGGGNTTYATGAARTCNGCNGGNTTYGARACNGARTTYGCNCCNATGGGNGAR GAYGTNGGNATHTAYATHGGNAAR------GARAAYCCNCCNGCNTAYACNGARMGNACN AAYGTNGCNACNGTNTCNGGNGCNACNCCNCCNGAYTAYAGYACNGCNTCNTTYCARGAR CCNCCNCCNACNTAYGAYTCNYTNTAYGGNMGNGTNAARGCNGCNAARGCNTCNTCNGAY GGNCAYGTNGAYTTYTTYAARACNATHATGGTNATHATHYTNGGNACNATHGGNTTYACN ATHYTNYTNGCNATHTTYATGGCNGTNCCNGTNTCNATGATHGTNATGGGNTCNGTNTAY ATHGAYGAYTGYAARGCNGARMGNATGATHCCNATHTAYYTNATHGTNGCNGGNTGYTTY GGNTGYYTNAARAAYYTNTTYAGYYTNGTNCARMGNTGYMGNAARAAYGARGARGARMGN CARGARGAYCARAARAARGTNCAYCCNGTNGARGCNATHGTNAAYTGYTTYATHTTYGCN TGGTTYATHGCNGGNTGYGTNTTYATHTAYMGNACNAARGAYGAY------TTYCARTCN CAYGAYACNGARGCNAAYTAYTGYGAYTAYACNYTNTAYTGGTTYTCNTTYTGGATHACN ACNTCNGTNTAYATHYTNATGGCNGCNAGYTGYYTNTGYGTNTGYTGYGTNGGNTGYGTN GCNTCNTGYTTYTCNCARAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYYTNATHAARATHATH GGNCCNAARAAYGAYCCNCCNCARATHATHCARGARAARGTNYTNGCNATGATHCARACN TGGGCNGAYGCNTTYMGNGGNAAYCCNGARYTNAARGARATGGARAARGTNTAYYTNGAR YTNAARCARAARGGNATHGARTTYCCNATGACNGAYYTNGAYAAYATGGCNCCNATHCAY ACNCCNGCNMGNAGYGTNCCNGAYMGNGARCARCCNGCNYTNAGYCAYGAYMGNGGNGGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARTCNCCNTCNATH AARGCNGCNAAYCCNTTYYTNCCNGARMGNCCNCCNAAYCCNCCNCCNYTNAGYGCNGCN MGNACNTCNTCNYTNMGNAAYGARACNACNTCNGARAAYCAYGARAAYTCNCCNCCNGGN CCNCCNAARAGYYTNAAYCCNTTYYTNTCNGAYAAYGARGARGAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TAYYTNMGNGGNAGYCARGTNTCN TGGATHGGNGAYTCNAAYAGYGTNYTNCAYTCNYTNATGCAYGGNTGYGCNMGNYTNGGN ATHGAYYTNAAYATHGCNACNCCNGTNGGNTAYGARCCNGAYGGNGAYATHACNATHGAR GCNATHAARATHGCNGGNAARACNGGNGCNTCNATHCARATGACNAAYAAYCCNGTNGAR GCNGCNTAYMGNGCNGAYGTNGTNGTNACNGAYACNTGGTTYMGNTCNGGNACNGGNAAR ACNGAYAARGAYAARAARYTNGGNGAYTTYCARGAYTAYAARGTNAAYMGNAARATGYTN AARGARGCNGGNGGNAAYTGGGTNTTYATGCAYTGYYTNCCNMGNGCNCARGARGARGTN ACNGAYGAYYTNTTYTAYAGYGAYGARTCNYTNGTNTGGCARYTNGTNGARAAYMGNATG TGGACNATHATGTCNYTNATGYTNAAYCARYTNCARGTNTAYACNCCNACNATHCCNATG CCNAARTAYGTNMGNGGNATGTCNGARGGNTCNGCNTCNCCNAARMGNCCNMGNYTNGAR TTYGAYGAYAGYTCNAARGAYGAYYTNCAYGAYAARTCNTCNAARAAYMGNGAYCARGAY GAYCARGGNAGYTAYAGYAAYTCNMGNAARMGNMGNGCNGAYACNGGNGAYGAYGAYGAY GAYGTNAARGAYTGYGAYGAYYTNAARTCNAARGCNGTNGTNGTNGAYGCNGGNMGNMGN GARCAYACNYTNGTNATGMGNYTNACNAAYAARGARCARGARGTNCARGARTGYATGAAY CARATHCARGARATGAARCAR---------------------------------CARYTN GAYCCNGCNATHAAYYTN------------GTNTTYCARMGNATG--------------- ---------------------------------------------------TCNAARGAR ATGGARGARCAYAARGARAARYTNAARCARAARCARAAYGARYTNAAYGCNTGGAARTTY ACNCCNGAYAGYCARACNGGNATGMGNYTNATGGGNAARTGYMGNATGYTNYTNCARGAR AAYGGNGARYTNGGNAARATGATHTCNTCNGGNMGNACNGCNMGNYTNGARGGNGARATH TCNYTNCAYAARGCNYTNGTNACNGARATGAARAARAAYCARAARGARYTNGAYGARTTY GTNGGNGARYTNGARGARGAYGTNGARGGNATGCARGGNATGATHTTYATGYTNCARCAR CARYTNAARGARGCNMGNGARCARATHACNMGNYTNCARCARGARAAYGARCARYTNMGN ACNYTNCARYTNCCNACNGARCCNGARCCNGGNGGN------------------------ ------------------------------------------------------------ ------------------GARMGNGGNGARGAYAARATHGARAGYATGGARYTNCAYMGN GGNCARGTNCCNGAYGARCARAAYAARYTNYTNAARGTNAARGTNGARMGNGGNGAYGAY ACNCCNMGNACNATGGCNGCNAARGGNMGNYTNACNAARTCNGCNAARGGNMGNGGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ACNTGYGAYGCNACNGARGTNGAYTAYGAYGARAGYGARCAYATHYTN ACNACNTTYACNYTNGGNTCNATHGTNTGGGCNAARATGGAYGGNTTYCCNNNNTAY--- ------------------------------------------------------------ ------------ATGTAYCAYGTNACNTTYATHGAYGARCAYGTNTCNMGNGCNTGGGTN MGNTCNCAYYTNATHACNTCNTAYGAYCCNMGNTCNGCNCCNGTNAAYAARGCNACNGCN AARTCNCARTCNTAYAARMGNGAYYTNMGNACNGCNATHTCNAAYGCNGARYTNGCNYTN AARYTNAAYYTNCARGAYMGNATHGAYAARTAYAGYTTYGTNAARMGNTAYTCNAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG GCNTCNTCNAAYAARTGGGARGTNGTNGCNAARGGNAARAARAAYACNGGNGARTCNCAR AARATGTCNCCNAARMGNMGNAGYGARTTYATHGARAAYATGCCNMGNYTNACNATHAAR GAYCCNATHGARYTNGAYTCNACNATGTAYTCNGCNTTYYTNCCNAARGARCARCCNCAR CARGCNGCNGTNGAYAAYTCNAARGAYGCNAAYAGYAARCARAAYGGNAAYAARAARGCN CCNAGYAAYAARAARAAYAAYAARGAYGAR------AARAARGCNAARACNGTNGAYATH AAYTTYGCNYTNTCNCARYTNGAYCCNAARGARYTNAARTCNGTNYTNGAYAARACNCAR TCNATGTTYCCNAGYCAYGARGTNATHTGGYTNAARGAYYTNGCNTCNTTYYTNAAYAAY AARYTNGARAAYGTNAARGAYTTYGAYCCNGTNTAYAAYGAYAARTCNTCNGGNTTYCCN YTNGAYGCNGTNCCNTCNGCNGTNGCNAARGAYYTNMGNACNTTYATGAARCARTTYTCN AARGARACNYTNGAYAGYATHTTYTTYTAYGGNATHAARACNATGTGYCARGGNATHGGN MGNGGNACNCCNGTNCAYGGNTTYAARGTNTTYYTNCARYTNATHACNCARACNAARTCN GAYACNGGNYTNGAYCAYATHCCNCARTAYYTNGARYTNYTNAARACNCAYCARAAYAGY CCNTCNAARTGYYTNTCNATHATGTGGGCNYTNGGNCARTGYGGNATGAARCAYTTYCAY TTYGGNYTNAARGTNTGGYTNGARYTNATGYTNCCNGCNYTNGARGTNMGNCARATHGCN CAYTAYCCNGTNGARTAYYTNGARAAYYTN---------TTYAARAARTAYTCN---AAY YTNCCNAARAARAGYTAYGGNYTNATHTCNYTNMGNGARTAYTTYCARGTNYTNGAYGTN TTYTTYTCNCCNAARTTYACNYTNGCNAAYGAYYTNAARGCNMGNYTNATHGCNGTNTAY CCNACNATHAARACNYTNGCNTTYGGNGARGCNCCNTCNGARACNYTNMGNAAYTTYTTY CCNTCNTAYTTYTCNMGNYTNGCNACNGCNAARGCNAARGAYACNMGNGARGARYTNYTN GTNTGYATGACNGARTGYYTNATHACNGAYAARCARTCNTTYGGNGTNTGGTGYCARYTN TAYACNAARCAYYTNGTNTCNTCNAGYMGNYTNYTNAGYCAYATHAAYAAYAAYTGGCCN AARYTNTCNTCNMGNTTYAAYAARAARATHYTNMGNGARACNYTNMGNTCNTTYTCNGTN ACNAAYGARGARCARGARGTNCARACNAARGAYAAYCARAAYGAYYTNAARYTNTGYCAR ---ACNACNAARGAYYTNACNATGAARGTNAAYGCNGCNCAYTTYCCNTGGGGNYTNYTN GTNTTYATHYTNGTNTCNGTNATHGCNGGNATHGTNACNTAYGAYATGACNTCNAGYCCN ACNTTYMGNTCNTCNAARAGYATGCARTTYYTNGARCAYTAYGGNATHYTNGCNYTNYTN GARAARGCNTAYCAYAAYGTNCAYCAYTTYTCNACNYTNTCNGTNAAYTGGGTNAARGTN AAYTTYCCNATHTTYTAYAAYCARGTNMGNGARACNGTNGTNCCNTTYTCNGTNACNGTN TGGAAYACNTCNMGNGARTTYYTNATHAAYGCNGARGTNCAYTCNMGNCCNTAYMGNGCN YTNGCNATGGARAARYTNATHCARTTYTAYTAYTGGGTNTAYGARYTNTCNCCNGARTTY TGGATHMGNTGYGARGARYTNGTNTGGYTNTCNTGGGAYYTNACNAARGAYTAYTCNTTY MGNGTNTGGACNCAYACNCARCAYTTYGCNGGNGARGCNCAYCAYTGGYTNACNGARCAY GTNYTNACNGGNTCNYTNTCNAARGARGCNATHAARGAYACNGCNYTNTGGGGNGTNGAR CAYATHCARAAYTGYACNACNYTNTTYGTNACNTGG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GGNMGNCCNGTNMGNGTNGCNACNTCNYTNTCNAAYGTNATGACNATGAAYGGNAAR MGNCCNCCNATHATHAAYAARTAYAARGCNGGNGTNGAYAGYGAYGGNAARATHCARTTY ATHCARATGGARTAYTAYATGGAYTGYGGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYACNGGNGCNTCNATHTCNCAYCAY YTNMGNGARGCNGARGAYMGNYTNAARGARTTYGGNAGYGTNATHTCNAGYGTNACNAGY CAYGGNCCNCARGAYGARATHTTYGARCARATHAARCAYYTNGAYAAYGARATHGARATG AARYTNAARACNYTNGARAGYGTNACNTCNAAYAAYCARAARGCNGTNCARGAYYTNGAR GAYGARAARGARGARYTNATHYTNAARATHAAYYTNTTYAARAARAGYATHAAYYTNTCN GARGAYGARYTNAGYCAYYTNYTNAARGARAARATGCARYTNGARAAYGTNCCNGAYGGN GARATHAAR---GCNYTNAARGTNAARCARYTNGARGCNGARGAYYTNATGTTYMGNAAR CAYYTNGGNATGGARATHMGNAARGTNAARGGNGGNTGYYTNCARGTNGCNTTYAGYCAR ATHGAYCARAARCARCCNAAYTCNYTNTTYYTNTTYTCNYTNAARTTYGAYGARAAYMGN CARTAYATHGCNTCNGAYTGYAARCCNCCNGTNTCNGAYYTNGGNGAYATHGTNCAYAAR YTNAAYAGYGAYAAYGAYTTYGGNAARTTYATHMGNACNATGMGNMGNAARTTYCARGCN TCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNAARMGNMGNTAYAGYGAYGTN------ACNGAYYTNTAYAARGGNCCNCARGAR TTYATGGARGCNGGNACNMGNGGNTTYYTNATHACNTCNATHCCNGAYMGNGARGARCAY TCNATHGAYGARACNGTNAARGTNYTNMGNAARACNTGYGTNAARYTNTAYGGNGGNGTN AARCCNYTNMGNMGNGARGAYGCNTCNTTYGCNAARGGNTAYATHATGATHGAYTTYATG GAYCCNGARACNGTNGTNTGYYTNCCNAAYCCNGAYGCNGARAARGTNGCNGARGARGAR GARGARGARGCNACNAARGARGARGGNAARGAR------------------ACNGARGAR ATGGARCAYGAR------------------------------AAYAARCARGARCARGAR GARGARGCNAARCCNGARGGNGARCCNGARGTNGARGGNGCNGGNGAYGARAARGARAAR ACNGARGCNGARGGNGAYGCNGARACNACNACNGAYGARGCNAARGARACNAARCCNGTN GARGARAARGARAARGAYGARAARAARAARAARGAR------------------------ ---------------------------------------------GAYACNMGNMGNMGN MGNGAYGARGARAARAARCCNYTNATGYTNGCNCCNTAYAARTTYAAYGCNTAYMGNACN GARYTNMGNAAYATHATGTTYATHAARTCNGAYATHCCNGAYCCNGTNGARGTNGTNAAY GCNTGYTTYGAYATGATGYTNGCNMGNAARCCNYTNTAYACNGAYTGYGTNAAYCARYTN YTNCCNGTNCARGGNGTNTGYGAYAAYGAYTAYAARCARYTNGARATHATGTGYMGNMGN GTNYTNGTNCCNTAYTTYGGNGARCAYYTNGARGARCCNCCNAGYTTYGGNGTNATGYTN ATHAAYAARATGTGYGARCCNGGNGCNGARGTNYTNYTNGARGTNGTNMGNAGYGCNATH TGGTGYYTNAAYCCNTGYGCNTGGCARTGYTCNCCNTGGGCNGARCCNGAYGTNGTNGTN CAYATHGARATHATHGGNAGYAARATHATHYTNAGYGCNATGCCNCAYTAYATGAARTAY MGNCARTAYAGYCCNTTYGCNGTNCAYGARYTNGGNTCNGGNAARCCNGARGAY------ ------------------GARGARCARYTNYTNAARGARATHAARGARGARAAYAAYTCN AARGARAAYAARGARAARGGNGGNMGNAGYGGNAARGGNMGNGAYMGNAARGAYGGNMGN GGNAARGAYMGNGARGAYAARAARAARCARCCNGAR---AARGAYCARGARGARAARAAR GARGCNGGNGAR---------------GARGCNAAYAARGAYACNGARAAYMGNGARAAY GTNGARAARGARCARGGNGTNGARGARGTNAARGARGARYTNCCNGARGARTCNGCNGAR CCN------------------------------ATGGCNGARGAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AARTAY ATGCARAARYTNYTNTTYAARAARGGNGCNAARACNMGNAARCAYTGGTAYAARCCNTAY YTNGGNGARGCNYTNGARGTNGARACNAARAARACNAARMGNACNGTNTCNCAYAGYCAY AAYATHMGNYTNMGNCARYTNAGYCAYGTNYTNTAYGAYAARGTNATHGAYATHATHAAY ACNGGNGARYTNTCNCARGARATGYTNGAYAARCARGTNTCNATHACNGCNGTNACNGTN ACNAARGAYGTNAAYAGYATHAAYATHTTYTGGGARGCNGAYMGNAARGAYTGGAARGAR GTNGARGAYYTNYTNGCNTCNCAYAGYGGNAARYTNMGNAGYYTNYTNATHTCNTAYCAY GTNYTNGGNMGNGTNCCNCAYATHGTNTTYGTNAARGAYAARTCN---CCNTCNAAYYTN CAYGARYTNACNGARYTNTTYGARAARGCNGAYTAYGGNCCNGAYTAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TGGCARAGYATHMGNACNCCNGGNAGYCCNACNYTNAGYCAYCAYGCNTGYGTNGTN GGNGARGAYMGNTAYATGATHYTNGTNGGNGGNTGGAAYGGNAARMGNMGNAGYGCNGAY GTNCAYGTNTAYGAYACNCARGARGAYAARTGGYTNCCNATHAARCARACNGGNTTYCAY GARGARGCNGGNYTNAGYTCNCAYACNGCNTCNATGYTNYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AGYGCNTAYGCNMGNTCNATHYTNACNGTNCCNTGGGTNGARATGGGNGAYAARGTNTCN YTNAAYTGYGAYAARACNGGNTAYCARGCNAGYATHATHTTYCAYACNAARCCNTTYTAY GGNGGNAARYTNCAYCAYATHACNGCNGAYGCNAARAAYACNAARACNGGNGARAGYATH TGYAARGTNCARGGNCARTGGAAYGGNGTNATGGAYTTYACNTAYACNAGYGGNGAYAGY CARTCNGTNGAYGTNACNCARYTNCAYGTNACNMGNAARTCNGTNMGNCCNATHGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARAARATH ATHCCNAARAAYGAYAARGARTGGGARTGGTGGATHAARTTYMGNAAYCCNCARGAYATH CARMGNCARCAYGARTCNTAYYTNTAYTGYGARATHGCNTTYTAYGTNYTNGGNTTYYTN ACNTTYTGYCAYGCNGTNTCNAGYGGNGGNMGNTAYAARTGGYTNTGGYTNGCNACNATH GCNCAYGGNYTNACNGTNGARTGYGTNAGYTAYTTYYTNCCNGAYATHGAYAAYTTYTGG CAYGGNCARTCNATGGTNGTNYTNATHGGNCARMGNYTNCCNYTNCAYATHYTNYTNGTN TAYCCNGTNTTYATHTAYACNGCNGCNGTNGCNGTNTCNCAYATGAAYYTNAAYTGGTGG GCNGARCCNTTYGCNGTNGGNYTNTCNACNGTNYTNYTNGAYATHCCNTTYGAYATHATG GGNATHAARYTNYTNTGGTGGACNTGGCAYGAYGAYGAYCCNAAYATHTAYGAYMGNCAY TAYTGGGTNCCNTGGACNTCNTAYTAYTTYCAYGCNGCNTTYGCNTCNTCNTTYGCNTTY ATHTTYTTYGGNACNAARMGNYTNTTYTCNMGN---GCNYTNAARTTYCARAGYAGYGGN TTYTTYGTNGARATGYTNYTNGTNYTNATGACNGGNYTNTTYTCNATGCCNYTNGGNGTN YTNCARTTYATHCCNATHTAYCAYCCNYTNCAYGAYACNYTNGGNATHCAYTCNGARGTN TGYGTNYTNYTNTTYYTNGGNTTYTTYGCNTTYGTNGTNTGGTGYTCNGAYMGNMGNCCN YTNGARTTYGCNMGNCAYAARGGNGGNAGYTTYTTYAGYYTNCCNATGYTNGTNGTNGTN YTNCAYTAYGGNYTNTAYGTNTTYYTNGTNTTYACNGCNAAYCCNAGYAARATHMGNGCN GTNGGNYTNCAYCARCCNGTNGGNCCNTGYAAYAARCARGTNAARGTNCARACNCCNTTY GGNCAYGTNYTNAARAARACNCAYTAYYTNTGYYTNAARAGYTAYTCNGARGAYTAYTTY ACNYTNGAYTGYYTNAARAARCCNCCNGCNAAYAARACNGARTGGTAYACNATHTGYGGN ACNCCNTAYCCNAAYCAYAARGARTAYATGATHGTNGTNAGYGCNTTYTGYATGYTNGGN YTNYTNTGGTTYTAYCARGCNYTNTGYMGNTCNGGNCCNCARCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ACNTCNATH GAYATHTCNATHATGAARCARTCNYTNATGACNTGGAARGAYTGGYTNMGNGARCAYCAR TTYTAYCARATHGGNYTNYTNTAYATGTTYACNMGNYTNTTYTTYAAYATHAGYCARGTN TAYTTYGGNATHTAYYTNACNAARACNATHMGNATGAARAARATGTAYGTNGCNATHYTN CCNYTNGTNYTNTAYGGNTCNAGYTTYATGGCNTCNATHTTYGCNCCNAGYYTNAAYAAR GCNGTNGGNMGNAARYTNGCNTAYGTNGTNGGNGTNGTNTTYGGNGTNAGYGCNAAYGTN TGGYTNTTYTTYATGGCNGARGGNAGYGAYCARGTNTAYGGNGCNGCNATGTTYYTNGGN ATHACNGAYTCNYTNATHYTNATHACNTCNYTNTCNATGGTNTCNGAYYTNATHGCNTCN AAYGTNGARAGYGGNGCNTTYGTNTTYGGNGCNATGAGYTTYACNGAYAARYTNTCNAAY GGNYTNACNATHYTNATHATHCARAARTAYGAYCCNTGYAGYTCNCARTGYGGNGGNGCN GCNGGNTAYTAYMGNTAYGTNGARTCNYTNGTNCCNGGNGGNGCNATHYTNTCNGCNTTY GTNATHYTNYTNACNYTNATHCCNCARACNATHGGNACNMGNMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGCNCCNATHCCNGARGAYAAYCAR GARAARCCNCCN---CCNMGNGAYGAYGAYGARTTYGAYTCNTTYCCNAAYGGNAAYYTN ---GCNCCNATHACNTTYGGNTCNGAYTCNAGYGAYGARAAYGAYGAYAAYTAYCCNGAY ACNACNGGNTAYATGYTNYTNCCNCARGARCCNGGNGTNGAYATHGAYGAYTAYGAYAGY GAYAAYAAYAAYGARAAYATHGARAAYCAYACNGAYAGYGAYMGNCARTCNGARYTNGTN GAYAAYGCNAGYGGNAAYAGYAAYAGYGTNATHCCNGAYCAYYTNCCNGAYGARGTNATH CARTCNGARGGNGGNGCNATHGCNCCNACNGTNACNGCNTCNAGYACNTCNYTNCAYCCN GARTTYYTNGCNAARTTYCCNGAYGGNAARGTNCCNTCNTAYATGCARGTNCCNGAYATH CCNTCNAARAGYAARGAYGCNYTNTGGAAYAARAARMGN---ACNGARAAYAAYTCNTCN YTNGARACNGCNGARGARAARAAYATHATHAARGCNATGTCNGGNTTYTCNYTNCCNACN GARAAYGTNCCNGAYTGGGCNAARAAYATHTCNGARGAYCARTGGAAYAAYGTNATHTCN AAYCARATHAARCCNTCNGARGARATHTCNGAYTCNTCNTCNCCNACNGTNCAR------ ---AARCARGARGAYTGGGTNGCNGARTTYCCNGAY------CCNGCNCAYGGNTTYYTN GCN---GGNGARAARYTNGARCCNYTNAARGTNGCNACNTTYAAYGTNCARCAYTTYGGN MGNGGNTAYYTNAARGAYAARCCNGARGCNAARCAYYTNGTNAARATHYTNCARMGNTAY GAYATHGTNYTNATHGARGARACNMGNGAYAGYACNAAYACNGCNYTNAAYACNYTNAAR AARAARYTNACNGARGCNGGNGARACNTGGGCNYTNGCNGTNAGYAARGARYTNGGNMGN AGYAARGCNTAYYTNGARCARTAYGCNTTYTTYTAYMGNGTNAARTCNGCNCARYTNGTN ACNTCNTAYCARATHAAYGAYACN---ACNGAYGAYTAYGCNMGNGCNCCNTTYTGYGTN GARTTYGCNTAYACNTCNYTNTCNAARAARTTYMGNGARTCNGTNGTNYTNATGGCNATH CAYACNCCNCCNGARGARACNMGNAARGARYTNAARGARYTNCCNGAYACNATHMGNTCN GTNGCNGCNATHTTYCCNMGNGCNGCNGGNGTNATHGCNYTNGGNGAYATGAAYGCNGAY TGYMGNTAYYTNTCNGGNAARTGGMGNAARTCNTTYGARYTNTTYAAYGGNGAY---GAY TTYAARAGYYTNATHGCNGAYACNGCNGAYACNACN---ACNGARAGYTCNGAYTGYGCN TAYGAYMGNGTNGTNYTNTTYGGNGAYTAYYTNCARGTNACNAAYGCNAARGTNTTYGAY TAYMGNAARTGGYTNCAYYTNAGYGARAARGARGCNYTNGCNGTNAGYGAYCAYTAYCCN GTNGARTTYGTNYTNCAYAGYTTYAGYYTNAAYYTNTGYGTNGGNCCNACNTAYGAYCAR GAYTGYGCNYTNCAYTTYAAYCCNMGNATHGAYGAYAAYAARGTNGTNMGNAAYCAYATG CARGGNGGNAGYTGGGGNACNGARGARACNGCNGGNGGNAAYCCNTTYMGNAARGGNCAR CAYTTYGARATHCAYATGAARGCNCAYCAYCAYGGNTAYAARATHACNGTNAAYAAYMGN CAYTTYTGYGAYTTYGGNAAYMGNYTNCCNMGNGARAGYATHCARTAYATHTAYATHGAR GGNGARGTNATGATHACNTAYATHCARTTYMGNGGNGGNAAY------CCNTCNTAYGGN CCNCCNGGNGTNCCNGGNTAYCCNCCNGCNGTNCCNAGYTAYCCNCCNGCNCCNAGYTAY CCNCCNGCNCCNAGYTAYCCNCCNGCNCCNTCNTAYCCNGCNGCNCCNGGNTAYCCNGGN CARGGN---GGNCCNATHTAYAAYCCNCCNGTNCCNTTYACNACNGCNATHCARGGNGGN GTNATGCCNGGNAARATHGTNTTYATHTCNGGNGTNCCNAAYCCNAAYCCNAGYMGNTTY ACNYTNAAYATGCARTGYGGNCCNTAYGAYTCNGGNGAYTTYGCNATGCAYTTYGAYGTN MGNTTYAAYTAYGGNAAYGAYTAYAAYCARATHATHMGNACNCAYAARCARGGNGGNAAY TAYGGNAAYGARGARAARCARYTNGGNCARTTYCCNTTYTAYCCNAAYACNCCNTTYCAR ATGATGATHYTNATHGARCCNGCNTCNTTYAARATHGCNGTNAAYAAYCARCAYTGYGTN GARTTYTAYCAYMGNATHCARCCNTTYAAYMGNGCNGAYCAYATHAAYATHGTNGGNGAY YTNMGNYTNACNGARGTNMGNTTYCAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNCARGARATHGARGARGTNMGNCAR ACNAARGARAARGARATHAGYGAYTGGCARCARMGNYTNYTNTCNGARATGAARGARGAY YTNATGAARAARAARMGNAARCARGARATGGAYCARACNYTNAGYGARGTNACNAARAAR ATHAAYGAYGCNAAYMGNYTNATHGAYACNATGACNGCNYTNGARAARYTNMGNYTNATH MGNCARGAYGCNGCNAARAARMGNGGNGAYAGYGAYYTNGGNGARTCNMGNCARAGYTTY GARCARAARATHTCNGAYATGACNMGNYTNGTNMGNTCNCARYTNGARGTNTAYAARGAR GARGARGAYAARYTNMGNGGNGTNYTNMGNTCNGARCARGARGARACNAGYAARAARGAR AARCARYTNCARGARAAYAARGAYYTNGARGARCARMGNCARAARAAYGARGAYYTNMGN AARATGYTNTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYTTYMGNGTNTGYTTYTTYGAYGAYTTYTCNTGGAARMGNGARACN ACNTAYYTNTTYYTNMGNAAYAAYGTNCCNGAYTTYCARAARYTNAARTCNAAYYTNMGN AARCARAARGGNTGYMGNGCNTAYTGYTGYCARTGYGCNTGGMGNGAYGTNACNTCNYTN CARGARATGTCNGAYCCNAARYTNAARTGGGTNTGYGGNAARCAYGAYTCNCCNGCNAGY GTNATHGARGCNYTNATHTGYTTYTTYTCNATHTGGTCNGTNGTNGGNYTNGCNGGNTTY CAYTCNTAYYTNACNGCNTCNGARATHACNACNAAYGARGAYATHAARGGNACNTTYACN TCNAARMGNGGNCARGAYAAYTTYAAYCCNTTYAGYAARGGNTCNYTNTTYAGYAAYTGY ATGGGNATHYTNTGYGGNCCNGTNCCNCCNAGYYTNYTNGAYMGNMGNAARYTNATHGTN CCNGARYTNGARTCNCCNGTNCCNAAYAAYATHGTNGGNATGMGNGCNGTNAGYGAYMGN ACNGTNACNGTNGTNACNGAYCARATGAGYCAYGAYCARATHAARAARCAYAGYATGATH AGYTAYCARGGNCCNGAYGGNTCNATHTCNAAYAARGTNCCNAAYGTNAAYGGNACNGTN GGNGGNATHGGNCAYMGNGTNAAYATHTAYCCNACNAGYCARGGNGARGTNAAYTAYTAY MGNGAYCCNCARGGNATGGGNCCNCCNAGYAAYCCNTAYATHCCNGCNACNGGNTAYGAR AARGAYAGYCAYAARTAYCAYGCNTCNMGNGGNGTNTCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CAYYTNATHAARTGYMGNGTNAAYCAYMGNGGN TGYAARATGACNGTNTGYCCNYTNGAYCAYACNCAYGTNGTNCCNAARCCNGARYTNAGY CAYCAYYTNACNCARTGYGAYAARMGNAGYYTNATGGAYMGNGAYYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATHTTYGARACNACNGAYCAYATGAAR ATGGCNCARGCNGCNGGNATHMGNTTYGTNAARAGYAGYAARGCNTAYMGNTAYCCNGAR AARACNYTNAGYAGYYTNTGYGTNATHCCNCCNGTNCCNTCNATGYTNMGNGAYGTNTCN GARGTNAAR------MGNGAYYTNACNACNCCNGTNTCNYTNCCNYTN---ATHGAYAAR TGYATHAAYAGYGAYGARGGNTTYGCNTTYCARTCNTAYCAYAAYGGNYTNGARGARTTY GTNTTYATHTCNGAYGTNGCNCARATHYTNAARGTNCARGARAGYTTYGCNAGYCAYGTN ACNCCNACNGAYATGCCNGGNAGYAARATGGCNACNAAYACNAARGARGAYGAYAGYGTN CCNTCNTAYACNAGYAGYMGNACNAARGAYACNGAYMGNCCNGARTCNTTYAARMGNGAY GGNTCNATHCARAAYYTNCCNGTNTGGATG---ACNMGNYTNAAYMGNAARTCNACNGAR TCNTCNGTNTCNAGYYTNGARAGYGAYGARCCNGARTCNTCNTTYAARTTYACNAARACN GTNTAYYTNATGAGYGARAARGARYTNAARGARATGGCNATHCARGTNATGAARCARGCN GGNMGN------------------------------------------------------ ------ATHMGNACNGCNTCNGGNGCNAAYTCNMGNTAYGTNYTNYTNCCNGARGTNCCN CCNGAYACNGCNGARACNAAYGCNGTNATGMGNACNGAYCARYTNCCNCARTTYTCNCAR ATHACNCCNTAYTCNTGYATHACNGGNTGYGCNAARYTNTCNATHGARTAYGARACNAAR YTNGARAARCAYATHGAYACNYTNAARGAYCCNAARGTNGARAARACNTTYGAYAGYGTN TAYYTNCCNATHGARGARATHGCNGTNCCNYTNAAYACNGCNTGGTCNACNGTNAARAAY YTNCAYTAYGTNGCNGCNAGYGAYGAYTAYMGNMGNGCNTTYTCNAARGTNCAYCCNCAR GTNGARMGNGTNAARAAYGARMGNTGGGTNAGYCARCCNYTNTAYTAYTCNTTYGARGAR YTNGARGCNAAYGGNGCNAAYYTNACNGAYTAYCARAARMGNYTNGTNAAYYTNTAYYTN YTNGARGGNAARYTNAAYGGNGTNCAYYTNTCNGCNGARGGNAGYTCNCARYTNGTNGAY MGNYTNAARYTNATHGCNAARGARAGYCARAAYTTYMGNAAYAARGTNMGNATHTGYACN GAYATHTTYTCNCAYGAYGTNATGAAYTTYAAYGARATHGAYGARATGCCNTGGCCNYTN YTNGCNCARATGTCNAARGAYMGNTCNAAYCCNACNMGNGGNCCNTGGMGNGCNACNYTN CARCCNGCNATGTAYCARGCNATGATGAGYTAYTGYAGYCAYMGNATGACNMGNTGGAAY YTNTGGAAYGCNCARCAYAAYMGNGCNTCNCAYAAYCAYGCNAGYGARTAYYTNAAYAAY AAYATHYTNGTNGARAGYYTNMGNTCNTAYMGNTCNGAYGTNGCNACNATGYTNGGNTAY GAYAAYTTYGCNGARATGTCNATGGARACNAARATGGCNGGNTCNGTNGARAAYGTNYTN ACNATGATHGARACNYTNMGNGCNMGNTTYGCNCCNGCNGTNTGGGARGAYGTNGCNCAR YTNCARGAYTTYGCNACNGCNGARGGNTTYAARCAYTCNYTNGARATGTGGGAYGTNGCN TAYTGGMGNMGNMGNCARMGNGARCARYTNTAYAGYGTNAARAARGAYGCNATHAARGAR TAYTTYCCNGTNAAYTCNGTNYTNYTNGGNYTNTTYGAYYTNTGYACNAAYYTNTTYGGN GTNAAYTTYGARGARGTNACNCCNGARGTNGARGTNTGGAAYCAYGAYGTNMGNTTYTTY AAYGTNACNGAYAGYGARACNGGNGARCAYATHAGYTCNTTYTAYTTYGAYCCNTTYGAY MGNCCNGGNAARATHTCNTCNGGNTAYATGGAYYTNGGNMGNGAYAAYAGYGARCAYGTN GGNACNTGGCCNTAYTCNTAYYTNTGYYTNMGNATHCCNMGNCCNAARTCNTCNTCNGAR CCNGCNYTNATGMGNTTYGARGAYATHGARACNATGTTYACNGARTTYGGNCAYGGNYTN CARCARATGYTNACNAARGTNCCNTAYAGYGARATHGCNGGNCARAARAAYGTNGARTGG GAYGCNGTNCAYATHTGYGCNAARTTYATGAARYTNTGGYTNTCNAAYCCNAAYGTNATH AARAGYYTNAGYAGYCAYTAYAGYACNAARGARACNATHCCNGAYGGNATGGTNTCNGAY ATGYTNAARGCNTCNMGNCAYTGGAGYAAYTTYGAYACNATGCAYCARYTNTAYGTNTCN GCNTTYGAYATGGARGTNCAYATGACNAAYACNCAYTGGCAYAGYGTNATGAARCARYTN TGGGARAGYTTYATHCCNYTNCCNYTNTCNGARGARGAYAAYYTNCCNTGYTCNATGATH CCNATHTTYTGYGARYTNTAYCCNGCNGCNTAYTAYTCNCAYATHTGGTCNGARATGGTN GCNGCNGAYATHTTYTCNGCNTTYCARGARGCNGGNYTNGARGAYCARGARAARATGAAR GCNYTNGGNMGNMGNTTYMGNGARACNTAYYTNACNYTNGGNGGNGGNGTNCCNTCNTGY GAYGTNTTYMGNCARTTYMGNGGNMGNGAYCCNTCNACNCARGCNYTNCAYCCNATGGAR AAYAAYAAYGCNATHGCNGCNAARACNGARCCNGARGAYGARGCNAARATHGARGAYGTN AARCCNACNGTNGCN------GARGAYAAYGAYTCNTCNCCNACNAAYAAYATGAARGGN GGNMGNGGNTAYMGNAARGAYGCNAAYCCNGARACNGARACNGCNAARGGNGCNATHMGN MGNAARATHTGGGAYAAYYTNGARGAYAAYAAYYTNGTNTCNATHCCNMGNCCNTGYCAY TAYMGNATHCCNAAYTTYGARGGNGCNTCNGCNGCNGCNGAYCARYTNTCNACNYTNGAR GARTTYAARACNGCNCARACNATHAARGTNAAYCCNGAYAARGCNCARGARCAYGCNMGN TTYYTNGTNYTNGARGGNGARAARGAYYTNGTNYTNYTNAAYCARAAYCARAARGAYYTN ATGGTNCCNACNCCNGARYTNAARTCNGGNYTNYTNAAYMGNGTNGTNCCNCCNGARGGN GCNAAYAARGARGARYTNMGNCAYTGYTGYACNACNCARGGNGTNAARGARAAYAGYAAR GARATHGGNATHGARGAYAARGTNAARYTNGAYYTNATHGTNGTNGGNAGYGTNGCNGTN TCNMGNAAYGGNTAYMGNATHGGNAARGGNAARGGNTAYGCNGAYYTNGARTAYGCNATG ATGMGNACNATGGGNGCNGCNAGYGCNGAYACNGTNGTNGTNACNACNGTNCAYGAYTCN CARGTNGTNGAYATHGCNGAYGAYYTNGTNGAYGARCAYGAYATHACNGTNGAYTAYATH YTNACNCCNACNGARGTNATHAARACNAAYGCNACNMGNCCNMGNCCNTCNGGNGTNATH TGGGAYCAYYTNGARGTNGCNAARTTYTAYCARATHCCNGTNYTNMGNCARYTNMGNAAR AAYGARMGNGAYGAYGGNAARACNGTNYTNYTNAARGAYCARAARGARGARGAYGARGAY CCNGTNGAYGCNATGGARCCNCCNCARCCNMGNMGNTAYGTNMGNTAYTAYAARAAYGAY GGNGGNTAYMGNGGNMGNGGNMGNTAYTAYGGNGGN---MGNTAYMGNMGNGGNGGNMGN MGNMGNCARTAYGAY---------------------GARAAYGGNGARGTN------GAY TCNGGNGCNGAYGGNGAYAAYGARGGNMGNGGNGGNAAYMGNMGNCCNCCNCCNMGNAAY AAYTTYMGNAAYMGNMGNTTYMGNMGNGGNGGN---------AARGCNMGNGCNTCNGAR TCNGARCAYAGYGAYGGNGGNAAYAARGAYGGN---GGNGAYGGNGARGAYMGNCCNMGN CARMGNMGNTAYAAYACNAAYMGNMGNMGNTAYAAYCCNAAYAAYGAYMGNMGNMGNMGN TTYGAYAAYMGNMGNGARAAYMGNMGNGAY------------GAYCAYTCNGGNAGYGAY GGNGARCARAARTAYTCNGCNGAYGARGGNGGNGARGGNMGNMGNCCNCARMGNCARMGN TTYMGNACNAAYCCNGARGCNGTNGTNTTYGTNGGNGCNYTNTCNMGNAAYYTNMGNGTN AGYGARYTNAARACNGARYTNMGNAGYCAYAAYGTNAAYCCNGTNMGNYTNYTNTGGMGN GGNGCNAAYGGNTAYGCNTTYYTNTTYTTYATGGARCCNGAYAAYGCNAARCARGCNGTN GGNGCNYTNACNGGNMGNGARYTNAAYGGNMGNGARATGAARGTNGARATGGCNAAYATG GAYMGNGAYMGNMGNMGNTCNAAYMGNAAYGAYMGNGGNMGNGARGARGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNACNGAYAARTCNGGNMGNAGY--- ---YTNTGGYTNMGNCCNGTNAARGGNTAYTAYTTYTCN---CCNCARTTYAAYCARTTY GCNGTNGARAAYACNGTNGAYTTYCCNATGMGNGARGAYGAYGTNYTNYTNGTNACNTAY CCNAARACNGGNGTNCAYTGGTCNTGGGARATHYTNMGNATHYTNGTNACNGGNGARATG GARAAYAARGAYATHGGNAARGARAAYTAYATGATHGARTGGAAYCAY---CCNGAYCAR TAYGARTCNYTNCCNAGYCCNMGNGTNYTNAAYAAYCAYYTNCCNTTYCAYYTNCARCCN ACNGAYYTNYTNAARAARAARCCNAARGTNGTNYTNTTYTAYMGNAAYTTYAARGAYGTN GCNGTNTCNTTYTAYCAYCAYCAYTGYGGNATHAARGARTAYGGNTAYGARGCNGGNGAY TTYGGNGCNTAYYTNGGNMGNYTNYTNGARGGNYTNATGGARGGNGGNAAYCCNTTYAAY TTYCAYAARGARTGGGARGARGGNATGAARAAYCAYCCNGAYYTNCCNGTNTAYTGYTGY GCNTAYGARGAYATGAARGAR--------------------------------------- ------------------------------------------------------------ ------------GAYCCNGTNTCNGARATGMGNAARGTNTGYGARTTYYTNGGNAARAAY CAYGAYGAYAGYTTYYTNCARGARGCNGCNMGNACNACNAGYTTYGAYCARATGAARAAR ACNTTYGGNCCNGCNAAR---------------CCNGTNTTYTAYMGNAARGGNCARGTN GGNGAYTGGAARAAYCAYTTYACNGTNGCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARACNTTYYTNCAYAARCARMGNMGNACNYTNAARCARMGNCAR TCNGCNYTNACNGCNGCNAARCARGARYTNAAYAARGAYAGYAGYATHYTNCARCAYTCN AAYCCNACNAAYGARGCNACNGARGTNYTNGAYAARGTNMGNGAYACNYTNGARTCNGAR ATGYTNCAYGTNGAYGCNYTNCARTCNAARTTYGAYACNGAYTCNAARYTNYTNAARGAR AARGARGARAAYTAYAAYMGNYTNGARGGNATGGCNAARGARAAYGARAGYGARGAYGAR TCNGARTAYAGYCCNTTYGGNMGNCCNTTYCAYGGNGTNAARATHCCNAAYATHGAYYTN AGYGARGAYGARAGYAGYGGNGTNAGYAGYTCNGARGCNAGYATHGAYGGNTAYTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TTYGGN GTNGTNTAYCAYGGNCARYTNMGNACNYTNGAYTGYGCNGTNAARGTNCARMGNMGNTCN GARGARMGN---AARGAYTCNACNGARCARATHAAYAGYGARYTNTCNGCNYTNYTNMGN TAYCARCAYGARAAYATHGTNACNYTNTAYGGNTAYGCNYTNGAYGGNCCNCAYYTNTGY YTNGTNTAYCARTAYYTNMGNAAYGGNTCNYTNGARGAYMGNYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GCNACNTTYYTNAARAARACNTAYGGN------AAYAARATHAARAGYTCNAARAAY AAYGTNTCNYTNCARYTNGGNAARGGNGTNTCNYTNACNAGYTCNATHAGYATHGCNAAR AAYYTNCARMGN------GARAAYAGYAAYGGNATGAGYYTNGARGAYMGNATGTCNGTN GARCARTGGYTNGAYTAY------------AGYGGN------------TAYGARAAYGCN GGNGAYMGNGARMGNATGGGNYTNGTNGTNAARGAYYTNAAYAGYTTYATGAARGAYAAR GCNTAYTTYGTNGGNGCNACNTCNACNGTNGCNGAYGTNTTYYTNTAYCAYAGYYTNTTY CCNGTNTTYGARMGNATGACNTTYCAYGARAARGARAARTTYATHAAYYTNTCNMGNTGG TTYAAYYTNATHCARAGYGAYGARAARGCNMGNCARTCNYTNYTNCCNATHACNTTYYTN MGNACNATGATHTAYTCNAGYATHGGNCAYCAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNCAYGTNYTNGARGTNGARYTNGAYCCN TCNAAYYTNGCNGARGTNTGGAARGCNATH---ACNGCNTTYATHCCNAARGAYTCNMGN ATGAARMGNGAYAARACNTGYTTYTCNACNCAYGTNGTNMGNACNGGNTCNTCNGARAAR TGGMGNYTNMGNYTNGARTGYAGYAAYTCNGARYTNGTNGAYYTNATGAARGGNGTNGTN ACNTGYYTNAGYGTNGARAARTAYACNGTNTCNTCNYTNAAYAARGTNGCNCARAGYAAR TGYGGNATGGGNMGNAARGCNAARYTNGCNGARCCNATHTCNYTNGAYAARGCNGTNGAR TGYGTNAARAAYCAYYTNGARYTNAARCAYGTNAGYYTNGCNAARGTNGAYGGNAARGAY GAYGAYYTNATHAARACNGTNGCNGTNTGYGCNGGNTCNGGNTCNAGYGTNYTNAARAAY GTNAARGCNGAYYTNYTNGTNACNGGNGARATGTCNCAYCAYCARGTNYTNGAYGCNGTN CAYGCNGGNAGYCAYGTNATHYTNTGYCAYCAYAGYAAYTCNGARMGNGGNTTYYTNAAR GAYYTNCARAARMGNYTNAGYAARTCNATGGARAARTCNGTNCAYGTNTTYGTNTCNGAR TGYGAYMGNGAYCCNYTNGARATHGTNGARCAYCARTCNGARACNYTNTGYATGTAYTGY YTNTCNTGYAARYTNCCNGTNTGYACNACNTGYTCNACNGAYGGNMGNCAYATGACNCAY GARGTNCARCCNYTNCCNACNYTNTGYAARTCNCARAARAGYGARYTNTCNCARAAYYTN CARTCNYTNTCNGARAARGCNAARTCNGGNACNGARTTYATHCARMGNYTNAARAARATG GCNGAYAGYGTNAGYGCNMGNGTNAARGCNCAYAAYCAYGCNGGNGARTCNGGNTAYAGY GAYATHGTNAAYYTNCARACNGCNGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TCNAARYTNGARAAR YTNATGYTNAARGTNGTNCCNYTNGARCCNGGNGAYTGYYTNGGNTGYAARATHGTNGGN ACNTCNGTNATGATHGCNAGYGGNATHATHGTNYTNACNTCNGCNATGGCNGGNMGNAAR MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AARAARCCNCCNACNAAYYTNGARGARTTYYTNGAR GCNGARGGNYTNGAYGAYTGGCCNYTNCCNATGAGYYTNGARGGNCCNYTNCAYATHGAR TCNGARGGNYTNTTYATHGGNAAYCARGAYGAYATHGCNGAYATHYTNAAYGARGCNGCN CCNYTNGGNYTNCAYATGYTNGARGCNATGGARGAYMGNYTNTCNACNYTNGARGGNAAR ATGAAYTTYTAYTCNGAYCARATHGTNACNGAYACNAARMGNCCNTCNMGNYTNGCNGAR MGNYTNTTYCAYTCNCCNACNAARACNTTYATGACNGAYATGTCNGAYTCNGAYGCNYTN AARTCNCAYMGNAGYTCNAARGGNCAYMGNAGYGTNGAYYTNATGGAYACNATGATGGAR ACNMGNAARMGNAGYYTNGAYTAYTAYGTNTTYCCNGGNTTYGCNCAYGGNGARTTYATH GARYTNCCNGCNCARYTNGARGCNCCNCCNATHYTNCAYMGNATHACNAAYGCNCARGAY TTYAAYTCNGGNTTYAARAARTTYTGGAARAARYTNTTYYTNTCNGARGCNTCNTCNGCN GTNATGCARGAYGCNTTYTGGTGGATHTTYYTNGAYATGTTYAAYAARACNGARGGNTTY GARGARGAYAARGAYTGYATHTTYGAYMGNATHGCNGAYAGYTAYGTNGCNYTNTTYACN AGYATHAAYACNGAYGTNAARGAYAARTTYYTNTCNGTNTAYCCNAGYTGYYTNTCNCAR GCNYTNTAYTAYACNTTYMGNGARGCNTTYCCNGARTCNAARTGGMGNTTYGAYGARACN TTYAARCARTAYYTNGTNAAYYTNGTNTAYGARTGGGTNACNGGNYTNMGNCCNYTNCCN GGNGTNTGGAARTCNTGGAGYGARGAYGGNYTNGAYGGNAAYCARACNAGYMGNGARAAY GARACNGCNAARAARATGYTNGARGCNGCNGCNYTNAAYAARAARGTNGARYTNAGYYTN GAYATGGAYTCNTTYGCNAARGTNATHGAYAARYTNGGNACNGARCCNGAYCCNACNCCN ATGGGNCAYATGTCNMGNGARATHACNAARACNAGYAAYMGN------ATHTCNGCNCCN TCNMGNGGNAARTCNCAYATGTTYAARCARGARTCNCAYCARATHGGNCCNGGNCCNGAY TAYGARMGNGTNAARTTYAAYACNTCNGGNMGNAGYCCNYTNATHGCNCAYTAYYTNCAY ATGMGNCARYTNMGNAGYTAYAARCARCCNGGNATGAARGTNMGNMGNACNGARATHYTN AARYTNCCNCCNGAYGGNCCNACNTAYCARCARTTYATHGCNAAYACNYTNAAYAARGCN GARTCNYTNGARAARCARTAYACNMGNATHTGYGAYCARACNTCNACNGCNATHYTNGAR YTNGARMGNTAYAARMGNGAYTCNAAYAARGARATHGGNGARYTNAARAARGCNYTNACN AAYATHAARAGYATHCCNGARMGNMGNTCNYTNATGGARAARATHTCNGARTAYAARGAY YTNATGATHAARGARMGNCCNYTNATGGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TAYGGNTCNCCN GTNCCNAAYAGYTTYACNAARAAYACNYTNMGNGTNGTNAAYGTNTGGATGGAYGGNTTY AARAARTAYTAYYTNCAYATHAAYCCNMGNGCNAARGAYATHGARTTYGGNGAYATHAGY GARMGNYTNGCNYTNMGNAARAARYTNAAYTGYMGNTCNTTYGARTAYTAYYTNAARAAY GTNTAYCCNGARATHYTNAAYAARTTYCCNGAYATGAGYAAYTCNYTNAAYGGNAAYGGN GGNGAYGAYAARGGNACNTTYYTNCCNGARYTNCCNATHMGNGCNAARGGNATHYTNAAR CAYAARGGNTCNGGNYTNTGYGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNCCNCAYTCNGCNCCNTCNCCNGCNMGNAARAARGARGTNAAYTTYGAYYTNGAYMGN ------MGNTCNCAYCARCCNTGGATHCCNGCNGGNTAYGCNCCNTGYAARCARCAR--- MGNGCNMGNTCNTCNAGYGCNGARMGNAGYCCNTTYTAYGTNAARACNATGGGNGAYCAR GARYTNTGGGAYTAYYTNCCNGARMGNMGNAGYGTNACNGTNCARGAYAARCAYMGNGAR GCNGCN---------TAYGGNTAYMGNTCNYTNCCNACNGARMGNCARYTNMGNTCNTGY GAYGTNTCNGAYTCNTTYGTNGAYYTNATHGARAARMGNATHYTNCAYMGNATGYTNCAR GARAARMGNGGNGGNGGNCARATGMGNCARTCNMGNAARATGYTNTAYAGYAGYAAYGAR GCNYTNGAYATHACNGAYYTNACNGTNGAYAARTCNTAYGAY------------------ ---GAYACNAGYYTNAAYACNACNGCNGARGCNGCNAGYATGGTNGAYGCNCCNACNYTN GARAAYATHCARYTNAARYTNGCNGAYATGGARMGNACNMGNMGNGARATHMGNCARMGN TGGTCNTCNYTNAARTTYATGGAYACNAAYAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TTYGCNTCNYTN MGNATGGAYMGNMGNGAYAGYGAYGAYTTYGAYGAYGAYYTNMGNTCNYTNGARTGGYTN CARAGYGARGAYYTNYTNAARAAYATHGGNGGNGARAARYTNGAYAARGARGAYGGNTGY GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TCN GAYGTNAAYACNCARGAYTCNGAYCAYGAYACNCCNYTNATGTTYGCNGCNTGGAAYAAY GCNCCNMGNATHGTNGCNTCNYTNATHAARCAYGGNGCNGAYGTNAAYAARAARAAYMGN TAYGGNAGYACNCCNATHTGGAAYGCNGTNTAYCARTCNTCNGCNGARTGYGTNYTNATH YTNYTNAGYAAYAAYTCNACNATGGAYGCNCCNTGYGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TCNTTYTTYYTNYTNGCN------------YTN ATHGGN---------GCNATHGGNYTNGTNAAYTGYCARTTYGAYMGNGAYAAYAGYMGN GAY---------MGNGAYTTYGAYMGNGARMGNGGNMGNGARGARMGNTTYGCNMGNCCN GCNGARGGNTGYACNGGNAARGTNATGGAYATHTTYTTYYTNATGGAYTCNTCNTCNTCN ATHTAYATHAAYGAYTAYATGTCNCARCAYMGNTTYGTNAGYAAYATHATHMGNAARTTY GAYATHAGYAGYGARGCNACNMGNGTNGGNATGYTNACNTTYAGYGAYGAYYTNGARMGN CCNGTNYTNGGNYTNGAYCARTAYAAYGGNMGNGCNGARYTNYTNAAYAGYATHTCNGTN CARAAYYTNCCNTAYMGNACNGGNGTNACNAAYACNGAYATGGCNATHMGNTAYGTNMGN CARYTNACNAAYTTYMGNCARGAYATHACNAARGTNATGGTNYTNYTNACNGAYGGNGGN TCNMGNTCNCCNAGYTCNACNGCNMGNGARGCNGARYTNGCNMGNAAYTCNGGNTTYTAY ATGTAYGTNGTNGGNATHGGNCARTAYYTNGARGARMGNGARTGGMGNGCNATHGCNACN GAYCCNGAYGAYAGYTTYGTNTTYAAYATHACNAAYCCNMGNTTYYTNGARGAYGTNCAR TTYACNYTNCCNACNMGNGCNTGYGCNYTNCCNCCNATHATHYTNGGNGGNTCNTGYGAY ATHAGYMGNATGTCNGARATHTAYTTYGTNGCNGGNMGNGGNGCNCARAAYGAYGCNCAR ACNTTYYTNGARAAYTTYGGNMGNMGNACNMGNGAYCARMGNGAYGTNYTNMGNGTNAAY TAYYTNGTNGAYGGNTGYGTNGCNGTNGARGAYATGACNYTNYTNAAYGARGARCCNTTY YTNTGYGARMGNTAYGAYMGNGCNGGNAAYGTNGTNAGYCCNGTNGGNGCNTCNGARATG TTYTCNMGNGCNGTNMGNTCNATHACNGARAGYMGNGGNMGNGAYACNAAYCAYGTNATH GTNYTNTTYGTNGAYGARGAYACNATGAGYGTNGAYMGNTTYGARYTNGCNAAYAGYGCN MGNAAYGCNCARAAYTTYCARGGNGCNACNGTNGTNGTNGCNGAYYTNGGNGTNMGNACN TAYMGNGARTTYGCNCARMGNATHGCNGGNGGNMGNAAYAAYTTYATHAGYTTYAAYAGY GGNAGYYTNTCNAGYCARTCNAAYGCNCARATGAAYYTNYTNAAYTCNATHTGY------ ATGGCNGAYAGYACNAAYAAYCCNGAYYTNYTNYTNGAYAGYCARCCNGARATHACNGGN TTYGCNAAYGAYGAYTTYGARAARGTNGAYGCNCCNGGNAGYGGNTTYGCNCAYGAYGAY GTNTCNGCNGCNGCNTCNGGNGCNTAYGARTAYGAYGTNGAYCARGAYGCNGARATHTCN ACNACNGCNGAYGCNGAYGTNGTNGGNGARGARGARGCNGARGCNGAYMGNTTY------ ---TCNGGNTCNCAYGAYGARCCNGCNTAYCCNTCNGCNGARCCNYTNATHTCNTGGGGN GAYGAY---------------------------------GARAAYGAYGARGTNTCNGCN CARGTNCARCCNTCNGCNCCNGTN------CCNGARAAYAAYGARCCNYTNGTNAAYTTY GAYGAYAGYTCN---CCNGGNCAYGAY---TAYATGCARTCNTTYATGCCNTCNGTNCCN CCNACNAGYGARATH------GAR---ACNTCNGARCCNAAYYTNTCNTCNTCNAGYAAY CCNYTNCARACNCARYTNGAYGARTTYGARGARAGYGARAGYGTNAARGARCAYAARCAR GAYTCNGAYCARACN------ACNGTNGARTCNGCNAARGGNTCNTGGYTNAARGGNGTN GAYCCNMGNAAYACNGAYATHGAYGAYTCNTTYTCNAAYGTNYTNATHGAYYTNATHTAY TGGMGNGAYGTNAARACNACNGGNATGGTNTTYGGNACNATGYTNGTNGTNYTNYTNTCN YTNGCNATHTTYTCNYTNYTNAGYGTNYTNGCNTAYYTNTCNYTNGCNGTNYTNGTNGTN ACNTTYAGYTTYACNGTNTAYAARAARATHATGGGNGCNGTNCARAARTCNAAYGARGGN CAYCCNTTYAARCARTTYATHGAYATGGAYATHACNYTNAGYGARGAYAARYTNAARAGY GTNATHCARACNGTNYTNAARAAYGTNAAYTGYACNGTNAGYGARYTNMGNMGNYTNTTY YTNATHGARGAYATGGTNGAYTCNATHAARTTYGGNYTNYTNYTNTGGGTNTTYACNTAY GTNGGNGCNTGGTTYAAYGGNATGTCNYTNATHATHYTNGTNGTNGTNAGYATHTTYACN YTNCCNAARGTNTAYGARACNTAYAARGTNCARATHGAYAAYTAYATHGCNATGGCNAAR GGNCAYGTNGAYAAYGCNATGACNATHGCNCARAGYAARYTNCCNTTYYTNAARAARAAR GARAARGCNCARGTNAGYAARMGNTTYTCNTGGYTNAARMGNTAYGGNCCNGARTTYCAY ATHMGNGGNGAYCARGTNCARATHATHTCNGARCCNMGNCARTTYTAYGARATHYTNAAR GTNAARATHAARAARGCNAARMGNMGNGTNACNYTNGCNTCNYTNTAYYTNGGNAAYGGN CARYTNGARCARGAYYTNGTNACNAGYATHGAYGAYGCNTGYCARGCNGTNYTNTCNCAY GGNTCNTCNGAYYTNGAYGTNAAYATHYTNYTNGAYTAYACNMGNGGNTCNMGNGGNACN GTNAAYTCNMGNACNATGYTNTGYCCNYTNYTNGARAARTGGCCNAAYGTNAARGTNGCN YTNTAYCAYACNCCNGAYYTNMGNGGNTGGYTNAARAARATHYTNCCNGARMGNTTYAAY GARACNATHGGNYTNACNCAYATGAARGTNTAYYTNATHGAYGAYAGYTTYATHATHAGY GGNGCNAAYYTNAGYAAYGAYTAYTTYACNAAYMGNCARGAYMGNAAYATHYTNTTYAAY GAYTGYCCNCARYTNGCNGAYTTYTTYAAYAAYYTNGTNAARTGYTCNATGTCNTTYTCN YTNCARYTNCAYGGNGAYGAYTCNYTNCAYYTNGCNCCNGAYTGGAAYATHCAYCCNTTY YTNGAYTCNGAYAAYGGNTTYAAYTTYAARYTNGCNGCNAARAARAARATHGARCARTGY YTNCAR------------TCNCAYCCNATHTTYGARMGNGAYGARACNTCNGAYTAYGAR GGNAAY------GARAGYAAYYTNATHAARGAYATHGGNACNGAYACNGTNGTNTAYCCN YTNGTNCARATGGGNCCNTTYGGNGTNCARAAYGAYGARATGGCNACNGTNGARYTNTTY YTNMGNTCNGARCCNTCNGAYYTNATHYTNYTNTCNTCNGGNTAYTTYAAYYTNACNGAY CARTAYACNGAYGTNATHGTNGAYGAYGCNGAYTCNMGNTTYAARATHYTNATGGCNTCN CCNAARGCNAAYGGNTTYYTNGGNGCNAARGGNATHGCNGGNGCNGTNCCNTAYTCNTAY ATHTAYYTNGCNAAYCARTTYTAYAAYAARGTNTTYAARGCNGGNCARTCNCAYMGNATH AAYATGYTNGARTAYGARMGNGARGGNTGGACNTTYCAYAGYAARGGNYTNTGGTAYTAY YTNAARAAYGAYCCNYTNCCNMGNYTNACNYTNATHGGNTCNCCNAAYTTYGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AARACNAARAARYTNCCNAAR AARAARAARAARAARCCNGTNACNTCNCARACNCAYMGNCCNGTNAGYAAYCCNAGYTCN GARTCNTCNMGNCAYTAYMGNYTNAAYYTNGCNGARATHCCNTTYGTNGCNGGNAARTCN ACNACNGCNAGYCAYTCNYTNGGNGCNAAYGTNCARAARGTNYTNTCNATGATGAARTCN CAYAAYACNGCNYTNTGYTCNAAYCARCAYCARCAYCAYCCNGAYTCNGGNCARMGNTCN GCNAGYCCNTCNTCNTCNMGNTCNGGNTCNAGYGCNACNTCNTCNATHGAYCARGAYYTN ACNGAYYTNYTNAAYCARYTNCARGARGARTTYMGNCARYTNAGYAGYGAYCAYCARGAY YTNGCNCARCARYTNAAYTGYGCNACNGAYAARGGNGARAARYTNGAYYTNGARCARGAR ATHGARGTNATGGTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TCNTCNGCNTCNTCNCCNCARCAYCCNCARCAYCARTCNGARGGNGTNTAYGGNGCNAGY GGNGTNCCNACNGTNGAYAGYAGYGGNTCNAGYACNGARTCNCCNTCNCARAGYGCNGCN GAYTCNYTN---CARCARACNAARATGGGNYTNTCNTTYMGNGAYGGNTCNGTNAGYMGN TCNGTNMGNGCN---GAYAARCCNTCNTCNTCNACNCARTCNTCNCCNCCNGARGGNYTN GGNCCNAAYTTYGTNCARTCNTCNGAYGTNGARGAYGTNTCNGGNGGNATHGGNGGNAAY ACNGAYTCNGCNYTNTCNCCNTCNTCNAGYYTNCARGCNTCNAAYMGNAARMGNGGNATG GGNMGNGTNMGNGGNCAYGARGAYGCNAGYGGNGGNGGNGGNGGNGGNCARTCNTCNTCN TCNTCNTCNTCNGCNCCNAARTCNTCNTCNTCNYTNCCNAARTCNTCNGCNTCNTCNTCN TCNCARMGNCCNGCNCCNAGYTCNACNGCNGCNGARGTNCCNAGYGGNMGNGGNTCNCAY AARATHCCNGGN---------------GAYAARTCNGGNMGNYTNTCNGCNTAYGAYTTY CCNGAYGAYAGYCCNGAYGARGAY------AAYTAYATGGCNYTNGCNGCNMGNTCNAAY MGNAGYAARTGYCCNGTNGAYAGYTCNGARAGYAAR---ACN------------------ GCNGCNGCNGCNGAYGAYGGNGGNAARGTNGGNGAYAARAGYGARGGNYTNGARTCNTCN TCNTCNTCNTCNTAYCCNGAY---GGNGCNAARCCNCCNAARGCNMGNTTYGCNGGNMGN YTNAGYAGYGGNGARGCN---GTNGAYGCNGGNGTNTCNTCNGTNGAYAGYAGYACNMGN TCNGAYAAYAARCCNGGNCCNGAYGGNGCNGGNGTNGAYAGYTCNACNTCNTCNTCNCCN MGNGAY---------------ACNGCNGAYGGNCARGCNTCNGAYGTNGTNGAYTCNGAY ---------TTYAAYCARGGNGGNGAYGGNGAYGTNGGNAGYGGNGGNCARTCNGCN--- ---------------------------TCNACNTCNGCNTCNAGYCCNTCNTAYTCNTCN TCNGGNCARCCNGTNGTNTCNAGYATGATHMGNGAYCCNGAYCARACNACNATGTGYTCN MGNGAYCARGARCCNACNCCNYTNYTNTCNGCNCARTAYGARACNYTNTCNGAYGAYGAY ------------------------------------------------------------ ------------------------------------------YTNTGYCCNTTYAAYAAR CAYAARGARTGGGCNCCNGAYATHGAYGAYGTNTAYATGGTNGARGAYYTNGGNAARGGN GTNGTNGTNTAYCAYGTNAARACNCARAGYATHGGN---GTNATHTCNCCNMGNAGYTTY GTNGCNGTNGGNGGNCAYGAYCAYGAYGCNYTNCCNATHYTNMGNTAYGGNGTNAGYGTN GAYTAYCCNAARCCNATHAARGARGAYGGNATGGTNMGNGGNATHTAYGGNCCNTAYGGN ATHMGNYTNGAYGARCAYCARGGNAAYCCNAAYCARACNMGNGCNGARGTNATHYTNCAR ATHGAYTTYAARGGNMGNYTNCCNAARAARYTNGTNGAYAARAGYATHCCNAGYTCNATH ATHACNTCNTTYAAYCAYTAYATGGARTAYATGAARAARAAYGGNYTNYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARACNTCNAAYTCNGCNGGN YTNGCNYTNGARAARGAYTCNGGNAARAARGARACNYTNACNYTNGARCARCARATHMGN AAY---AARCARATGGARGARAARGCNGAYAAYGCNGCNYTNGARGTNGTNATHAAYAAR YTNYTNGARTCNGGNCARAAYTGGGTNTCNGARGCNGCNMGNGCNCARYTNGAYGTNGCN AARGCNACNAARAGYCAYAGYACNYTNYTNAARAARGCNATGGAYGARACNTCNAAYATH YTNGAYAARGAYTCNGARTGGGARGCNGTNACNGTNGCNTAYAARGARMGNGARAAYGCN GTNACNMGNGCNAAYGARYTNGTNGAYGARGCNMGNMGNAGYATHGARAARYTNAARAAR GTNYTNGAYGARGCNAARGGNAARAARATHACNTCNAARAAYCCNGCNATHTAYCCNGCN ACNAARAARYTNGTNGAYTTYACNGARGARATGTCNAAYGCNGGNGCNCARGTNMGNAAR GCNGAYGCNGAYGCNAARGTNATGYTNAARTAYAARGAYYTNGTNGARAARGGNMGNAAR CARTTYCARYTNGARYTNGARAGYYTNACNCCNAAYGTNAARGTNGGNGGNAARAGYMGN AARYTNACNGAYGARGARYTNAAYGCNYTNATHGCNCAYGCNCAYMGNMGNATHGARCAR YTNCARAARCARATHTCNGARCAYYTNGCNATGGARMGNAARMGNYTNAAYATGGCNYTN GARGTNCARAARGARGARAAYAARGGNATHACNTCNTCNGCNGTNTGYGAYGARMGNGCN MGNYTNGTNACNGARTTYGARYTNGARAARCARAARATGGARATHGARTTYGCNTCNTGG ATGGARGCNGAYGTNMGNAARCARYTNAGYMGNCARGCNGCNGCNCAYAGYGAYCAYYTN AARGAYGTNYTNTCNGTNCARGARCARGARYTNAGYAARGAYTTYGAYMGNAARATHAAY ATHAARYTNYTNGARGARMGNGARAARTTYCARGCNGARACNGCNAGYTGGATHTCNMGN YTNAARGGNATHGARTCNGCNGTNGAYGCNMGNGCNGCNAGYGARAARYTNGCNCAYTCN GCNCARGAYYTNTGGYTNGCNTGYATHGCNYTNAAYTCNACNATHCARTTYGGNGAYGAR GARGARGAYCAYGCNCCNATHCCNYTNCARCARCAYGTNGARACNATGYTNATHTCNGCN AAYAARCAYCCNTTYGTNGARACNGTNGCNAAYACNATHCCNGARYTNGCNYTNGARMGN GGNATHTAYACNGARAAYAAYYTNMGNGAYMGNTTYGTNAARGTNGCNAARGTNAGYMGN MGNYTNGGNYTNGTNCARGARTCNAAYGCNTCNYTNTAYAARTAYYTNGTNTCNTTYYTN CAYTCNTTYTTYACNGTNAAYAAYGTNGCNGCNTAYTCNGARAARGAYTTYGTNTCNYTN GAYGARATGGAYAAYTTYAARYTNGTNGCNAAYGCNCARTAYTGGATGGARAARGGNAAY YTNGAYATGGCNGTNMGNTTYATGAGYCARYTNACNGGNGARTCNMGNAAYGCNGCNAGY GAYTGGATHACNGARGCNAARYTNYTNYTNGARACNMGNCARGCNGCNCAYACNATHYTN ACNTTYGCNTCNGCNACNGGNYTNGCNGCNACNTTYGARGAYYTNAAYYTNATHGARYTN YTNTGGAARCARGAYGTNGAYYTNGGNGTNGGNAARGARGTNTAYGAYCAYTCNYTNMGN GARGARYTNGARAARCARAARGARCARGARTAYTTYAARACNCARGARAARATHAARGCN CARGTNGCNGCNMGNGARAARGARGARAARAAYAARCARGARGARGCNAGYMGNTGGYTN AAYCARAAYTAYTCNMGNGAYGGNGARACNGGNGARTGGGTNAARMGNCARAAYAARGCN GCNACNAARGGNACNAGYAGYGCNAGYGGNTCNACNACNGTNGAYGARAAYGAYGAYTTY YTNACNYTNGARGCNGCNYTNGAYTAYATHTGYACNMGNGTNGAYTCNGAYGARTTYCAR TCNYTNGAYGGN------------------GTNGTNCCNGTNGCNAAYTCNTTYGCNAAY AAYYTNACNGCNTTYGAYTCNCCNACNGARYTN---------------CARCCNYTNYTN CCNGCNCARAAYGCNCARCARAGYYTNTGYYTNGARAAYCCNCARTCNTCNAAYATGGAR AAYGARTGGGAYCARGTNGARAAYTAYYTNAAYGTN------------TCNYTNAAYGCN CCNCCNATGACNGARGCNCCNCCNATGGCNGCNGCNGTNYTNGAYGARGCNYTNTCNGTN TCNGCNCARGAYTTYGAYYTNGAYGTNAARGCNGARATGYTNTCNCCNYTNGAYTCNGGN GTNGAYGAYGGNATHTTYACNAGYGCNAAYYTNCCNYTNATHCARGAYGTNTCNYTNTCN TCNTCNGAYATGGARCCNGTNCCNGAR---------YTNGGNCCNGTNACNYTNACNAAY TCNAGYATGCCNCCNCARCCNTGYGCN------ATGAAYACNTCNYTNGAYTGGGARGCN GGNAAYATGACNATHTTYGGNAAYYTNAGYGCNYTNCARCARGAYAAYATHGAYGAYATH GAYYTNGARAAYATGGAYGAYYTNTTYAAYACNATG------------------------ ACNGARGCNAAYGAYYTNYTNGGNAAYGTNACNAGYCCNGAY---------------GTN GAYAGYYTN---GTNYTNTCNACNACNCAYAAYGAYACNGTNAAYTCNYTNCCNTCNACN TCNTTYTCNGARCARYTNGCNGAYACNTTYGAYGGNYTNGARGGNGCNACNGGNGGNGCN GAYTAYAGYGGNCCNACNGAYGGNYTNGAYGCNCCNTAYMGNAARATHTCNMGNYTNTCN GARTCNGGNTCNGAYTCNGGNTTYAGYGGNAARGGNGCNTTYAGYTCNTCNTCNTCN--- ---TCNGCNTCNTCNTCNTAYACNGGNAGYCCNACNGAYTCNTCNATGGGNAAYAAYYTN ACNAAYTCNAAYGAYACNGAYCAYGAYCCNCAYGGNACNAARGTNTTYGCNCAYCARGTN GCNCAYAAYCAYACNTAYAAYACNYTNCCNGGNCAYGTNCCNMGNGARGTNAARAARTAY GCNCCNAARCARCAYTCNAARAARGGNCCNCARTGYMGNGAYGARAARAARGCNAAYGAR YTNAARATHCCNATGAGYGTNGAYGARATHGTNGARTCNCCNGTNGARACNTTYAAYGAY YTNYTNACNAARTAYAGYYTNAGYGARGARCARYTNACNYTNATHMGNGAYATHMGNMGN MGNGGNAARAAYAARYTNGCNGCNCARAAYTGYMGNAARMGNAARGTNGGNGCNATHGTN AAYYTNTCNGAYGARATGGTNGAYYTNCARAARGCNMGNGAYMGNYTNGTNGARGARMGN GCNGARATGGARMGNGARTCNMGNMGNATGMGNGARAARTTYGGNCAYYTNTAYACNCAY ATHTTYGARTCNYTNMGNGAYGARCAYGGNCARCCNTAYGAYCCNAGYYTNTAYTCNYTN CARCARTCNAGYGAYGGNAAYGTNTTYYTNGTNCCNMGNAAYGTNACNACNACN---ACN TCNTCNACNACNGAYATHAAYGGNAAYGGNTCNACNAAYGGNACNGGNAGYGTNGARMGN AAYGGNMGNATHAARAARMGNMGNGCNATHTCNTCNYTNGTNYTNTTYGCNATHGGNYTN GTNTTYGCNATHYTNACNYTNYTNAAYYTNGCNTAYATGYTNATHMGNAARGGNCCNAAR AARATGTTYTAYAARAARAARMGNGAYGARGARCCNGCNTGYYTNMGNGAYCCNATHTAY GGNGARCAYGGNTAYYTNCAYYTNGARGARGTNMGNATHCAYTAYGTNATHAGYGGNCCN TCNGARAARCCNYTNATGYTNTTYYTNCAYGGNTTYCCNGARTCNTGGTAYTCNTGGMGN CAYCARATHAARCAYTTYTCNAARGAYTAYMGNGTNGTNGCNATHGAYATGMGNGGNTAY GGNGAYTCNAGYMGNCCNGTNGGNGTNAAYMGNTAYAARYTNGARTGYYTNGTNAARGAY GTNAARCARATHATHACNGCNYTNGGNTAYAGYTCNTGYATHYTNATGGGNCAYGAYTGG GGNGGNGCNGTNGCNTGGTCNTTYGCNGGNTGYTAYCCNGARATGGTNGARAARGTNATH ATHATGAAYTGYCCNCAYGTNMGNGTNTTYAARAARTAYYTNCARAGYCAYYTNGCNCAR TTYAARAARAGYTGGTAYATGTTYTTYTTYYTNGTNCCNTTYYTNCCNGARATHTAYATG GGNYTNAAYGAYTAYAARCCNTTYGAYGTNATGTTYAARGGNMGNMGNCARGGNGTNCAR ACNGAYGCNACNACNACNGARGAYGTNGARGTNTAYAARTAYYTNTAYCCNAAYMGNCAY GCNTTYAAYGGNCCNATHAAYTAYATHMGNGCNGCNYTNTTYAAYGGNTCNTCNTCNTGG YTNTCNCARAARGTNACNAARCCNGTNYTNYTNATHTGGGGNTGYMGNGAYYTNGCNYTN GARACNGGNYTNGCNGCNTGYTGYAARGAYTAYGCNTAYGAYYTNAARATHGAYTAYYTN AARGAYTCNAGYCAYTGGGTNCARATGGAYCAYGCNGARCARGTNAAYTCNTCNATHMGN AARTTYGTNACNACNAAYGTNTGYAAYATHGTNATGTTYTGYAARATHGGNTTYAARGAY ACNTTYAAYATHTCNYTNATGGCNYTNTCNGTNTCNGAYYTNGGNAGYTCNATHGTNYTN TTYTGGATGGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGYTNAAYAARATHACNACNYTN TCNMGNTTYATHCCNMGNGTNMGNAAYGCNMGNTGYATG---GGN------GGNGTNCCN GCNAAYTTYAARCCNYTNACNCARGTNTGYYTNGARACNAARAGYCAYATGAAYTTYATG CCNGTNCCNCARGGNTCNTGGCARGCNGCNCAYAGYGCNAARAAYTCNMGNTAYAAYATG YTNYTNYTNGGNTCNATHGCNTCNACNATHGCNACNTTYACNACNYTNTAYGCNACNGAY TGYATHTAYYTNCAYGGNCCNCCNCCNTAYTGYAAYYTNAARGAYAARAGYTCNAARATH AARGTNCCNCARMGNTTYCAYAARYTNGTNTCNGARAAYCAYACNYTNYTNGARAARTGY TCNACNGCNAARYTNGTNAARAARATGCCNAAYTCNGAYGCNGCNCAYAAYTTYATHGAR MGNYTNAAYCARTCN---AGYGARGTNAGYCARGARYTNTGGGCNAARACNAARGCNATG ACNTGYYTNCARAGYCAYAAYYTNATGYTNAARTCNYTNAARTCNYTNGGNATHGARGCN ATGTCNGARACNTCNTCNTTYGAYACNGTNTAYMGNGCNAARMGNYTNYTNGARTTYATH YTNTCNAARTTYGCNCARACNCARGARGARGCNGAYTAYTTYTCNAARGTNCARTTYMGN CCNTCNCCNCARCCNTCNGTNATHGAYAARGGNGTNMGNGARTCNYTNTTYAARAAYCAR GCNCCNGAYACN------------CARATHGTNAARCARMGNAAYGAYTAYTTYGTNGTN GAYGCNYTNATGAAYTCNAARACNTGGGCNMGNYTNCARTTYGARAARGAYYTNTAYCAR YTNCARYTNCARATHYTNTCNYTNTCNGARTCNGAYTGGTGGGARTTYYTNACNCARGAY CCNGARAAYGGNGGNACNGTNCARATGATHCAYAGYYTNYTNACNTCNAGYGGNGARTTY TTYCCNGCNATHGTNGGNAAYCCNTAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AGYTCNGTNCAYGAY CCNATHAAYGAYYTNCCNGARCARATHTTYGTNGCNYTNGARTGYYTNYTNGAYGAYAAY AAYGAYCARGTNMGNAARGCNGCNGCNATHACNYTNTAYTCNYTNGAYMGNCCNTCNGAR AARGCNAARGTNMGNYTNMGNGARATGYTNAAYGCNGARAAYGCNGTNGAYMGNTGGGCN GGNTCNCARTGYYTNGCNCAYTAYGGNGARTGYGAYTCNGAYGTNGTNGCNGARATHATH AARCARATHYTNGAYTCNGARTCNGCNATHAARCAYGARCARGGNATGGCNYTNYTNGCN AARATHAGYAAYAGYAGYACNYTNGTNCAYTGYATGGTNGCNGARCAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNCARGAYAGYCCNGTNAGYYTNMGNGGNCAYAAYAAYGAYGTNGTNTGYTGYTGYTTY AGYCCNGAYTCNGCNATHYTNGCNACNGCNGCNTTYGAYACNAARGTNATHYTNTGGAAY ACNGAYACNCAYGARCARYTNAARGTNYTNGGNCAYYTNCAYCCNAGYCCNAGYYTNATH TAYGCNGGNGGNGCNAAYGAYCAYTAYGTNCARAGYGTNACNTTYTCNCCNAAYGCNYTN ATHGTNGGNTCNGTNTGYGAYGAYGGNTTYGTNMGNTTYTGGAAYYTNAAYGARGAYAAY GAYCCNGTNTCNATHTCNTCNGTNGGNGAYGCNATHTCNTGYTCNTTYTCNTCNGGNGGN GGNGTNYTNGCNACNGGNTGYMGNGAYGGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNGAYTCNTGYGTNMGNATGCAYAARGAYTTYATHTTYATGCCNGAYYTNATHGAY GCNACNTAYMGNTCNGAYACNGCNTGYAGYTTYGGNMGNMGNTCNYTNAAYAGYGARACN TAYTTYCARATHGGNYTNCCNMGNGGNGGNAAYCCNGGNGARMGNACNTTYCAYYTNGAR CARACNGCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNCCNATGTCNGCNMGNTCNGGNCAYTCNGTNTCNAGYATHAAYGGNACNCARMGNGTN CCNATHACNTCNCAYGAYCARAARAARATHACNTAYAAYGGNGAYYTNYTNGAYAARMGN TCNTAYTGYTTYACNGARCCNGAYMGNCCNTTYACNCCNMGNACNYTNAARACNAAYCAY CARTCNMGNYTNAARAGYTCNAARTGYTAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TTYAAYATHMGNCCNATHAARGAR GAYGARTGYGARCARGTNATGGARATGGTN------------------------------ ---TAYGARYTNGCNGARTTYGARAARATGAARGARMGNGTNMGNAAYACNCCNGARGGN YTNAARCARGAYATHTTYGGNCARCCNCARMGNTGYCARTGYYTNGTNGCNGARGAYACN AARAAYAARGARGCNGGNATHGTNGGNTAYGCNYTNTAYTTYTTYCCNTAYTCNACNTGG GARMGNACNTTYATGCAYYTNGARGAYYTNTAYGTNAARCCNGAYTAYMGNATHAARGGN ATHGGNAARAARATGTAYCARGCNTGYGTNCARATHGCNATHGAYATGGAYTGYGCNMGN GTNCARYTNGARGTNYTNGGNTGGAAYACNCCNGCNAARGARTTYTAYGARMGNATHGGN AAYGARAAYAAYACNGARGTNGARGGNTGGCAYAARATGMGNATGAARMGNGARGARATG GARAARTTYGTNAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CAYCAYCAYCAYCAYCAYCAYCARTCNCCNMGNCCNTTYACNTCNTCN GTNGCNCCNTCNCCNTCNTCNGCNYTNYTNCARCARAARAAYGARAAYATHACNCARYTN GARAARCARYTNGARAARGARMGNGARGARAAYMGNMGNYTNAARCARGARATGGARGAR AARGAYAARAARATHGCNGARYTNCARAARTCNGTNGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGYGCNCAY YTNTCNATHGAYACNGCNCCNGARTCNGTNYTNGAYACNYTNACNGAYGTNTGYCARGAR TTYTTYTCNCARGTNACNMGNCAYYTNGGNGCNGCNACNGAYMGNMGNGCNYTNTAYGAY AGYAAYGGNTTYCCNGAYTCNATHGARMGNGTNYTNCAYGARATHGGNGTNGGNAGYACN ACNGARYTNCAYTCNTTYTAYCARCARMGNATHATHGCNTAYCAYAGYMGNATGGARMGN CAYTGYCAYTCNYTNGTNACNGARTAYAAYACNYTNGTNAARCARCCNCAYTCNTCNTCN AARCARGTNTCNAGYTCNCCNAAYATGACNGGNGAYACNYTNCARGTNATHMGNATHAAR GARGARCCNAAYACNGGNATHCARTTYCCNYTNYTNGAYGAYAARGAYGAYGTNGCNGAR GCNGARMGNYTNYTNAAYATHGARAAYYTNGGNCCNTTYGARATHGTNGARCARGARATH CCNACNGGNYTNACNACNGARATGAARGCNAARGGNATGCARGCNAARGGNATHGCNTCN GARAGYMGNGTNTCNAARATGTCNATHTGGAGYTCNGTNGAYGARTCNAGYGAYAAYCCN AGYAGY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNGTNAGYGGNYTNCARGARGGNCARAAYGTNACNYTNCARACNTTYGTN GAYGARGGNAGYAARAGYTTYGGNTCNTGYGGNCAYTAYGTNGCNGAYMGNGAYGGNAAY GTNAAYYTNTTYAARGAYCARTGYCAYGGNGGNACNTTYGAYGGNYTNGARCCNATGGGN YTNTTYTGGAGYATGCARTCNYTNCCNGGNCARMGNCCNMGNMGNATHYTNAAYACNGAY ATHACNMGNCCNTTYGAYGTNCARATHGCNYTNCAYCCNAAYCAYGTNGAYTTYAARGAY YTNCCNTGGCCNGGNTGYCAYACNTCNYTNGCNTCNTGYCAYTTYTAYCARMGNTTYATG AGYCCNGARGTNAARGTNATHCCNGTNAAYGARGAYGGNATHGTNGGNACNTTYTAYATH CCNGAYGGNGARGGNCCNTTYCCNACNGTNATHGAYGTNTTY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CARTCNYTNAARAARGTNATGGTNTTYATHCAY GGNGGNGGNTTYTTYATGGGNTGYGCNAAYCARCAYGTNCCNGGNGAYYTNGTNGTNCAR GGNGAYGTNATHGTNGTNACNTTYAAYTAYMGNYTNTCNTGGYTNGGNTTYGCNAARGGN CCNACNGAYGARGTNAARGGNAAYATGGGNYTNTGGGAYCARYTNGARGCNYTNAARTGG GTNAAYMGNAAYATHMGNTCNTTYGGNGGNGAYCCNGAYGAYGTNACNYTNGCNGGNCAR TCNATGGGNGGNGARAGYGTNTCNGCNTTYAGYGTNYTNAARCARGCNAARCAYYTNTTY GCNAARGGNATHYTNATGAGYGGNACNATGTTYTCNAAYAARTCNACNGCNGGNTCNTCN GAYYTNYTNYTNGAYTGGYTNGTNAARAARACNGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATHGAYGAYYTNCARAARAARATG GGNGGNTTYGGNMGNTAYCARATHYTNATHTAYTTYYTNATGGGNATHGTNTAYATGMGN GGNTGYTGGCAYGCNTTYGTNAGYATHTTYCARGGNGCNGAYCCNGGNTAYCAYTGYMGN GCNGCNCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GARYTNTTYMGNGGNTTYYTNGTNTCN GARCAYAGYGAYGARAAYATHGARTTYTGGATHGCNTGYGARAARTAYAARYTNGTNAAR TCNCAYAARCARYTNGCNCCNYTNGCNAAYAARATHTTYAAYGAYTAYGTNGCNGTNCAR TCNMGNMGNGARGTNAAYYTNGAYTCNACNACNMGNAAYGCNACNGARAGYGTNACNTCN AAYCCNAAYMGNCARACNTTYGAYGAYGCNCARAARMGNGTNCARGCNYTNATGGARAAR GAYTCNTAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGGCNMGNTCNAAYGTNMGNTAYGARGTNYTNCCNTGYGARGARCAR AAYGTNGCNGCNGARCCNGTNGAYGTNGCNYTNGTNGTNCCNCCNCCNAGYTAYACNGAR AAYGCNGTNATGGARCARGAYGGNGAYCAYCCNGCNTTYGGNCCNGCNAARYTNCCNAAY TAYGTNGAYGCNACNACNYTNCCNTCNTAYGARGARGCNGARMGNACNAARGCNGAR--- GARTCNGCNGCNTCNTCNAGYAAYMGNGAYTGYGARACNGGNMGNATGAGYACNATHGAY GGNGTNAAYGARGCNACNATHGGNACNGAYGGNATGTTYATHTGYACNTTYTTYATHTCN TTYYTNTTYAAYTGGYTNGGNTTYYTNYTNTCNYTNTGYYTNTCNAAYACNATHGCNGGN MGNTGYGGNGCNYTNTCNGGNYTNGGNYTNTCNATHGTNAARTGGGTNGTNATHGCNAAR MGNAAYAAYTGGGGNACNGAYTTYGCNGAYGGNGAYTCNTGGYTNAAYYTNACNCARYTN CCNGAYCCNCCNGTNYTNGAYGARGARGGNAARAARAARYTNGCNAARAARTCNGARATG TTYGAYATHGAYGTNTCNGGNACNAARGTNCCNATHTAYGTNCARCARACNATHAAYAAY GARYTNAARACNTCNGGNACNATHYTNTTYYTNCAYGGNGCNGTNTTYTCNTCNCARAAY TGGCARGAYATHGGNGCNATGGAYCARGTNGCNAGYTGGGGNTAYMGNGCNGTNGCNATH GAYYTNCCNGGNAARGGNAARAGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TTYAARACNTTYCAYMGNATHTGGGCNGGNGCNTTYACNCCNGTNYTNNNNTGYTAY CAYCCNTCNACNGTNAARGCNGTNYTNAARTCNTCNGCNCCNAARCCNMGNGGNGGNATH ATHAGYACNCCNTAYGAYATGGGNTTYMGNTGGATHGGNGAYGGNYTNYTNATHGCNAAY GGNGCNAARTGGAGYMGNAAYMGNMGNYTNYTNACNCCNGCNTTYCAYTTYGAYATHYTN AARCCNTAYATHGAYGTNTAYAAYTCNTGYACNCARYTNYTNYTNAAYAARYTN---TCN YTNGARGGNAARTCNTTYGAYGTNTTYCARCCNGTNTCNAAYTGYACNYTNGAYGTNATH YTNMGNACNGCNTTYTCNTAYATGTCNGAYTGYCARACNGTNAGYGARCARAAYCARTAY GTNAARAAYYTNACNGARYTNATHTAYYTNTGGACNAAYMGNACNTAYAGYCCNCARYTN TAYAAYGARTAYGTNTAYAGYTGGACNGCNAAYGGNCARMGNTTYTAYAARYTNTGYGAY GAYGTNCAYMGNTTYTCNGARGARGTNATHAAYAARMGNMGNYTNGCNYTNGARGARYTN GARMGNAAYGGNTGYGARAAYAARTCNAARGTNAARGAYTTYYTNGAYATHYTNYTNACN GCNAARGAYGARAGYGGNGAYGGNATGACNCCNYTNGARATHMGNAAYGARGTNGAYACN TTYYTNTTYGARGGNTTYGAYACNACNACNAGYGGNGTNTCNTGGACNYTNTAYAGYYTN GCNTCNCAYCCNGARTGYCARGCNMGNGTNTAYGCNGARGTNATGGARGTNYTNGAYGGN MGNCARGARATHGARTGGGCNGAYATGACNAARYTNGARTAYACNACNATGTGYATHAAR GARGCNATGMGNATGCAYACNGTNGTNCCNTTYATHGARMGNAARYTNAAYGARCCNYTN GTNTTYGAYGGNCAYYTNATHCCNGARGAYACNYTNGTNGCNGTNCAYATHTGGGAYYTN CAYCAYAAYCCNCAYGTNTGGGARAARCCNCAYGARTAYGAYCCNGARMGNTTYAAYGCN GARAAYCARATHAARCARGAYCCNTTYCARTTYYTNCCNTTYTCNGCNGGNTCNMGNAAY TGYATHGGNCARAAYTTYGCNATGAAYGARATGMGNGTNYTNGTNTCNTCNGTNATHAAR AAYTTYGARYTNGTNAGYGAYAARGARAAYYTNCCNMGNAARTTYTAYGCNGTNACNATH AARTCNGARAAYGGNGCNAAYATHTAYGCNAARCCNMGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGTCN TCNGAY---GARATHGAYYTNATHAAYMGNGAYCCNAAYAAYYTNAAYGAYCAYGTNAAR GTNTGYTTYGAYGARGTNATHGGNGARCCNGAYGGNGCNCAYTCNATHAAYTGYGTNTGG ACNTGYAGYCAYTCNTGYTTYAAYTGYTGGAARAGYTGYTGYTAYAAYATHYTNACNATH YTNTGYGCNATHCCNYTNTCNATGTGYTGGGGNTGYGARTTYGCNTAYATHACNTTYTTY CAYGTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TTYACNGAYTTYTCNMGNYTNAGYCAYTCNGTNGGNAGYCAYAARGARCCN ACNGCNACNTCNAGYGGN---------------GTNCCNGAYACNAARGARYTNTGYMGN MGNYTNGARGAYAARATHAAYAGYYTNACNMGNATGGGNGGNAAYYTNCARAARGARAAY MGNGARATGGCNAAYYTNATHGAYMGNCARGGNGARAARYTNGAYACN------------ ------------------------ATGTCNACNTCNAARATHTCNGCNAARGTNTCNAAY TGGAAYCARGARACNAARACNMGNYTNAAYGARAARATHACNTCNAAYGTNAAYGAYGTN GGNTCNYTNGTNMGNCARYTNATHMGNGGNTCNAARACNAAYGARTTYYTN--------- ------GCNCARGCNGCNAARAAYTTY---GCNTCNCARGARAGYTAYATHCARAAYTCN ACNGARACNATGAARAARATGAAYCAYGTNMGNTCNCARYTNGARTTYCAR--------- ---------------------------------CARTCNGCNATHTCNMGNAGYYTNCAR CAYYTNGAYGARGTNCARGAYCARYTNTCNACNYTNCARCAYCCNGCNGAYAGYGCNYTN GAYTGGTAYYTNGARAAYATGAAYAARCCNGGNGAYCAYGTNGTNYTNGTNCAYGTNTCN CARTTYCARYTNCAYGTNGGNYTNCCNGGNGTNGCNGTNAAYGTNGARCAYGTNAGYAAR CARGTNYTNCARGCNAARGARCARTCNGARGCNATHATGAAYAARGCNYTNGAYATHYTN MGNGGNAARGAYATHCARGCNTAYACNGTNATHAARTCNTCNGCNAARCCNCARGAYGCN YTNATHGARGTNGCNGAYGARGARAARGTNGAYCAYATHGTNATGGGNACNMGNGAYYTN GGNACNATHAARMGNGCNYTNGTNGGNAGYGTNAGYACNGARGTNGTNMGNCAYGCNGCN ATGCCNGTNACNATHGTNAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARCARGAY AGYAAYAARGGNGGNGGNAAYTCNGAYGAYGAYAGYGAYGAYGAYGARGAYGAYGARGAY AARGAY---GARAAYGARAAYYTNAARGCNCCNACNGARYTNYTNATGGARTTYATHGAY TGYYTNATGAARAARGAYTAYCCNAAYGCNAGYAARYTNTGYAARATGATHYTNYTNTAY GARCCNGARAAYGARGARGCNYTNAARTTYCARCCNYTNATHGARGARAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------GARAAYGAYCARATHYTNGARATHGCNTGYYTNATHACNGARAARGAYYTNTCN ATHGTNGCNGARGGNCCNGAYYTNGTNATHCAYCARAGYGAYGCNGTNYTNGARGGNATG AAYGARTGGTGYGTNCARCAYCAYGGNGARTCNGGNYTNACNTCNGCNTCNMGNAAYTCN AARATHGAYYTNAARGARGCNGARAARATGGTNYTNGAYTTYGTNGARCARCAYACNCCN AARGGNAARTGYCCNATHGCNGGNAAYTCNGTNGGNATGGAYAARCARTTYATHGAYMGN TAYATGCCNAARGTNTCNGGNCAYYTNCAYTAYMGNGTNGTNGAYGTNAGYACNATHAAR GARGTNTGYMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNTAYAARYTNGTNTCNGTNTCNGCNAARTCNAARAARGARGTNGAYTTY YTNTAYCARYTNGARAARGAYTTYGARGARGTNGAYTTYTGGACNGGNCCNGTNYTNTTY CAYCCNAGYACNGTNYTNYTNCCNCCNCAYYTNYTNCAYGTNGTNGARACNAAYATGACN ACNGARGGNATHGGNTGGAARGARYTNGAYTAYGAYGTNCARCARATHGTNCARGAYGGN ATGAARAARACNCCNTCNAGYCCNMGNAARGTNMGNMGNGCNGAYGAYAGYGAYGTNATH GAYCAYACNAAYTAYCAYAGYTAYGGNGARATHGTNTCNTCNYTNMGNGARYTNAARGTN AARTAYCCNTTYAAYGTNGARATHTCNGARATGMGNTTYCCNACNCAYGARGGNMGNGCN GTNGTNATGGTNAARATHAGYGCNAARGAYTTYATHYTNAARMGNCCNTCNATHYTNATH GARGCNGGNATHCAYGCNMGNGARTGGATHTCNCCNGCNGCNACNYTNTTYAGYATHGAR AARTTYYTNAARAARTAYTAYAARGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNATGGGNMGNCARATGTGYTAYACNTGYCARTAYGTNYTNAAYGGNCCNGGNATH GARTGYGTNACNGCNCCNYTNAAYTGGACNGGNGGNGARCCNMGNATGAARTGYCCNCAR MGNTGYACNATHYTNGCNGARTAYGAYGCNAARACNTGYMGNCCNACNTTYTTYTTYMGN GGNTGYGCNGCNCCNACNGCNGGNCAYAARGAYGGNTGYAAYGARAAYGGNGCNMGNCAY AGYTGYATHTAYTCNTGYGGNGAYGGNGAYGAYTAYTGYAAYGAYCARTCNATHGCNMGN TCNCCNAAYTGYAARTCNAARGCNGGNGAYGGNGCNGAYGGN------------------ ------------------------------------------------------TAYTTY MGNYTNCCNTTYGAYCCNCCNMGNGAYTCNACNMGNYTNCARMGNGAYGTNTCNGTNYTN GAYCAYATHGCNTAYMGNAGYGAYATHCCNCCNGARAARCARGCNYTNAARTGYYTNGAR MGNTGGMGNACNYTNCAYMGNAARGGNGAYATHAAYCARYTNATHCARGTNYTNMGNGAY GTNAARAARAARMGNYTNGCNGCNGARYTNMGNAAYMGNTTYATHATHACNGTNAARTAY ATGGCNGTNTTYATHATHTTYYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNYTNGGNCAYACNTGYAAYGTNTGYGGNGAYTGYCARGGNAAYYTNGCNAARGARMGN GTNCARTTYGARTCNGTNATGGARCARGARTTYATHAARCCNYTNAAYAAYATHGTNGAY GTNGAYATHCCNAGYATHATHAARCARMGNAARGTNYTNAAYAARTCNATHYTNGAYATG GAYTCNGCNAARAGYMGNTTYCAYCARGCNGTNMGNCARTCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MGNGCNTAY GTNAAYTTYYTNAAYGCNGARGAYGTNTTYATHTTYMGNGAYAARTTYGAYGGNTAYGTN TTYYTNGAYGARAARGGNGGNGARTAYCCNGCNGTNGTNGARTTYGCNCCNTTYCAYAAR GTNACNAARAARMGNCARMGNAARGTNGAYTCNAARTGYGGNATGYTNGARCARGAYTCN GAYTAYAARMGNTTYYTNGARGTNYTNGCNAAYCCNCCNGARACNCCNTCNGTNTCNYTN GAYGCNATHGTNGARGARGTNGARGCNAARGARTCNMGNYTNGCNAAYATGGGNTCNATH AARACNAAYACNCCNYTNYTNGARTAYYTNAARMGNMGNAARGARGARAARMGNATGAAY ATGGTNAARYTNMGNGAYGARMGNMGNMGNGGNGGNGAYMGNGAYMGNGAYTAYGAYMGN MGNMGNTCNGCNAARGAYGARGGNGGNMGNAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARCARATHMGNGGNGGNGGNGARYTNTTYAARTTYCCNTGGACNTCNTTY TCNAARGTNCARCARTTYCCNTTYAARTTYTAYTGGAARCAYGTNMGNGTNTTYMGNTTY TTYTTYTAYACNAAYGCNYTNYTNYTNCCNYTNTAYGTNAARYTNACNAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNGCNGTNCCNAARATGMGNMGNACNYTNGARGGNGTNMGN GGNCAYCCNTAYACNMGNGTNTCNYTNTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------- >festiva ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHYTNTTYGGNYTNGTNCARYTNYTNTCNGGNGCNAGYGTNGARGAY AARTAYGARCCNATGGTNGCNTTYATHTGYGARMGNCCNGCNATGCAYMGNGGNGTNAAY GGNTGGYTNTCNGAYAARACNCARGGNTGYCCNGAYACNYTNGARGAYGTNYTNACNTAY TGYAARAARGTNTAYCCNGAYCAYAAYATHACNAAYGTNGTNGARTCNTCNMGNTTYTAY GAYATHCCNAAYTGGCCNATGGGNAAYGCNGGNMGNAARCAYACNCAYCAYGTNMGNCCN TTYMGNTGYYTNGTNGGNGAYTTYCARTCNGAYGCNYTNYTNGTNCCNCARCAYTGYGAR TTYGAYCAYMGNCAYGAYATHACNYTNTGYAARGARTTYTCNCAYTGGAAYMGNATHGCN GAYACNGCNTGYACNGCNAARCARATGCAYYTNGARTCNTTYGGNATGYTNYTNTAYTGY AARACNYTNGGNCAYTTYAAYGGNGTNGARTAYGTNTGYTGYCCNAAYAGYACNACNCCN MGNATHCAY------CCNGGNCCNCARAGYGAYGAYAARCCNGAYAGYTGGACN---AGY TCNGARGARGAYGAYGAYGAYAGYGAYGARACNGARGAYGARGAY--------------- ------------------GARGAYGARGAYGAYTCNAGYATH------------------ CCNGTNTCNTCNTCNGAYGARYTNCCNGAYGARAGYATHGTNGAYYTNTAYGARGCNTAY YTNMGNGAYCARCCNTTYCCNATGGARTAYAAYAAYGARCAYACNMGNTAYYTNGCNGCN AARGAYMGNATGAARAARAAYCARAARAARMGNGTNGCNAARYTNYTNCARGARTGGGAR AARGCNMGNGARAARGTNAGYATHGTNMGNAARACNGAYCCNAARAARGCNAAYMGNATG AAYGCNGAYATHGCNAARMGNTTYCARGAYYTNTAYGGNTCNTTYAARCARGARGAYGTN GCNGARMGNMGNCARYTNYTNGCNYTNCAYCARCARCAYATHCARGCNATHYTNAAYGAR MGNAARMGNGARGCNATGGAYCARTAYATGCARGCNYTNGARACNGGNGAYGTNGARAAR ATHATHAARTAYYTNCAYAGYTAYATHAARGCNGARGARAARGAYMGNATGCAYACNGTN AAYCAYTTYGARCAYATHMGNTAYTCNGCNCCNAARGARGCNYTNMGNATHCAYMGNCAY ATHATHAAYCAYYTNAARYTNTCNGARYTNMGNATHGAYCARGCNYTNGARATGYTNACN CAYTAYCCNTCNGTNGARACNCARGTNMGNCCNGARATHGARGARTTYATGAARMGNTTY AAYGCNATHGCNACNAGYATHAARAAYGTNGTNYTNCCNGTNCCNGTNATHGARGAYGAY AGYCARGARGARGARAGYAGYGAY---------AGYGAYGAYAGYGAYAGYACNAGY--- ------GAYATHAAYATHGAYGAYACNAGYGAYTTYGAYTCNAGYAGYGARGARGCNGAY AGYACN---------------------------------------TCNCARCARACNGAR GGNCARGCNAAYACNAAYGTNGTNGTNGAYGARGTNAARGARGAYGARCAYAGYTAYGAR ACNAAYCAYCAYTTYTCNGCNAAYGCNCARTCNGAYACNCAYAGYGTNAAYCAYGGNYTN CAYAAYACNGCNACNGCNGGNACNCARATHGGNAGYACNGTNGGNATHGCNYTNGGNAGY GTNAGYGTNTTYGTNATHATHGTNGTNGCNGTNATGATGATHCAYMGN---AAYMGNAAY AARGTNCCNGCNCAYGGNTAYGTNGARGTNGAYCCNTCNGCNACNCCNGARGARMGNCAY YTNGCNAAYATGCARATGAAYGGNTAYGARAAYCCNACNTAYAARTAYTTYGARGAYAAR CCNAARGAYAARYTNTAYAARCARATHACNGTNGARGTNACNGGNCAYGAYMGNGCNGTN YTNAAYAGYTAYCARAARTTYACNACNACNGCNGCNGARCARYTNGGNGTNCARATHGCN AGYATHTCNGARCCNCCNAARGTNATHACNMGNAARAGYYTNYTNAARTCNGTNTTYATH TTYAARAARCAYCARCAYCARTAYGARATHMGNACNYTNTTYMGNGTNTTYGARTTYAAR CAYYTNACNGARTCNACNGCNYTNACNTTYYTNGARTAYATHCARMGNAAYYTNCCNGAR GGNATHGCNATGAARGTNACNAARCAYGARYTNCARCCNYTNCCNGARCAYYTNAARCCN CCNGCNCARTCN------------------------GAYTAYTTYAAYGTNATGYTNGGN TCNCARYTNYTNTAYAARTTYGARMGNCCNCARTAYAGYGARATHYTNACNGARAAYACN GAYAARCCNATGTCNAGYATHTAYGGNGCNAAYCAYYTNYTNMGNYTNTTYGTNMGNYTN GGNGCNATGYTNGCNTAYACNTCNYTNGAYGARMGNACNGTNCAYATHYTNYTNAAYCAY GTNCAYGAYTTYYTNAARTAYYTNTCNAARAAYGGNCCNAGYYTNTTYAARACNTCNAAY TAYGARATHGCNACNCCNGAYTAYCAYMGNAARGCNATHMGNYTNGTNGARTAYATGGAR MGNGARTCNAAYCCNGAYGTNATHCCNCARAARTCNYTNGAYACNCCNGTNAARYTNGGN YTNTCNATGACNYTNATHGAYATHAARGAYGTNGAYCARMGNAARAAYGARGTNGARATH GAYGCNTGGYTNCARATGAGYTGG---AAYTGYGGNATHACNTTYGAYCCNACNGARTTY AAYAAYYTNCARGAYGTNMGNYTNCCNCCNTCNAARGTNTGGYTNCCNGAYYTNGCNGTN TAYAAYGGNGAYATHGAYYTNYTNGAYTAYATHGGNCAYCARAAYGTNYTNYTNCARTAY AAYGGNAAYGCNYTNTGGATHCCNCCNTCNAARATHMGNGTNTCNTGY------GAYYTN ACN------------GAYGAYAARACNTGYMGNATGAARATHGGNTCNTGGACNTAYAGY GCNCAYCAYGTNTAYYTNAAYGAYGARACN---AGYGTNGAYATHAGYTCNTAYAAYCAR GAYTCNAARTAYAAYGTNACNAAYGTNTCNGCNAARAARGTNGCNMGNACNTAYAGYTGY TGYCCNGARGARTAYCAYCAYATHYTNTTYACNTTYTCNTTYGTNAARAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ACNAARCARMGNTGGATHCCNYTNGAR TCNAAYCCNACNGTNYTNAAYAARTAYGTNCAYAAYYTNGGNATGGAYAARGCNTGGAGY TTYGTNGAYGTNTAYGGNYTNGAYCCNGARYTNYTNGCNATGGTNCCNMGNCCNGTNGCN GCNATHGTNYTNYTNTTYCCNGAYTCNAARTCNGARACNGTNGTNGGNAAYCCNATHGGN GARATHATGAARGARAGYCCNAGYGAYYTNTAYTAYACNAARCARACNATHGGNAAYGCN TGYGGNACNGTNGCNATHGTNCAYGCNYTNGCNAAYAAYCARGAYAARATHACNTTYGAY GARAAYAARCAYTTYTCNGCNTTYYTNAARGCNAGYTCNACNYTNAAYCCNGARGARAAR GCNAARTAYYTNGARGARGAYYTNAARATGGGNGCNGCNCAYGARGAYTGYGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TAYATGGARGCNMGNGAYGARATGYTNAARGCNGAYMGNAARACNAGYGTN GGNCARGGNYTNACNYTNACNAGYGTNGARCARGTNGTNTCNGAYGTNYTNGTNAARGAR AARAARAARYTNATGGARAGYAGYMGNYTNGGNGGNCCNGARTAYTTYCCNGCNACNAGY TTYTAYMGNTCNAARCCNYTNYTNGARAARACNACNATHTAYMGNYTNATHCARCARATG CCNAARGGNGCNGCNYTNCAYYTNCAYGAYATGGCNATHGCNAGYATHGAYTGGYTNGTN AARAAYGTNACNTAYMGNGARAAYYTNTAYATGTGYGTNAAYAARAARACNTCNTTYATG GTNTTYGGNTTYTCNAARAAYCCNAARAARTCNTCNTGYGTNTGGACNTCNGTNAARGAR GARMGNAARMGNGCNAGYAAYATHGAYGAYTTYGAYGARAGYATHAARMGNAAYATHAGY ATGYTNTCNTCNGAYCCNYTNGTNACNTAYCCNACNATHGAYGCNGTNTGGGGNMGNTTY TTYACNTAYTTYGGNCARGTNCAYGAYATGATHTTYTAYMGNCCNGTNTTYAARGAYTAY TTYAARCARGCNYTNAARGARTTYGCNGCNGAYAAYGTNCARTAYATHGARYTNMGNGGN ---YTNTTYGGNATHTTYGARYTNGAYGGNACNAARCAYGAYGCNGARTTYACNATHCAR CARTAYYTNGARGGNATHAARGARTTYGTNGCNGARAAYCCNGAYTTYTCNGGNGCNAAR TTYATHTGGAGYGCNATHMGNAAYAARCCNGARAARGCNYTNYTNGARAAYYTNAARAGY GCNATGAARYTNCAYGARAARTAYCCNAAYTCNGTNYTNGGNTAYGAYYTNGTNGGNCAR GARGAYCCNAAYAARTCNYTNYTNTAYTAYCAYAARGARYTNYTNTAYCCNAGYCARYTN ACNCCNCCNAARAARYTNCCNTAYTTYTTYCAYGCNGCNGARACNAAYTGGCARGGNACN CCNGTNGAYTAYAAYYTNYTNGAYGCNATHYTNYTNAAYACNACNMGNATHGGNCAYGGN TAYGGNYTNGAYAARCAYCCNAGYYTNGTNAARYTNGTNAARGARAARGGNATHGCNGTN GARGTNAAYCCNATHTCNAAYCARATHYTNGGNYTNGTNAARGAYYTNMGNAAYCAYGCN ATGGTNCCNYTNATGGCNGAYAAYGTNCCNATHGTNATHAGYTCNGAYGAYCCNGCNGCN TGGGAYGCNGCNCCNYTNTCNCAYGAYTTYTAYATGGCNTTYATGAAYATGTGYGGNGAR GAYGCNGAYYTNMGNTTYYTNAARCARYTNGCNATHAAYTCNATHCARTAYAGYGCNATG AAYATHGCNGARAARCARAARGCNATGAARYTNTGGCARCARAARTGGGAYAARTTYATH ---------------------------------------------------------TCN MGNGTNAARMGNGGNAAYTAYGAYATGYTNMGNYTNACNMGNGGNYTNAAYATGYTNMGN YTNGGNAARMGNGCNGGNTCNACNGAY---GAYCCNGARTTYAAYTCNGAYCARATHYTN ACNYTNGARGAYGARTAYCCNGARTCNTAYYTNTAYCARCCNTCNCCNGAYGAYCARAAR GCNYTNGCNGCNYTNAAYGGNGARTAYTAYACNTCNMGNGGNYTNMGNTAYMGNMGNTCN ACNCCNTCNGAYGAYCARATGGTNACNGCNGTNCCNGCNYTNGARGARGGNGAYGTNATH GARGAYGGNAAYATGAARYTNCCNAGYGAYYTNGARGAYGARTTYCCNTCNTAYTAYCCN ---AARYTNGCNTAYGCNGTNGTNGAYGAY---------------------GGNGARGGN GAYGARATHMGNTCN---------------------AARMGNCARTGGCAYATGYTNAAR GTNGGNGARAGYGARGAYGARGARGGNYTNAARATGTCNGARGARAARMGNGAYMGNYTN AAY---------------------------------------ATGYTNMGNYTNGGNAAR MGN---------CARTCNGARGARGARAARAARAAYATHAAYATGYTNMGNYTNGGNAAR MGNCAYYTNAAYATGYTNMGNYTNGGNAARMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNCCNACNMGNACNGCNGAYGAYATHYTNCARGAYTCNTCNGGNYTNGTN YTNGAYAARMGNCCNAARTAYATGGAYACNMGNMGNGAYYTNGAYGTNTTYAARGAYYTN GTNYTNATGAGYATHCARGARYTNGTNGAYGARGGNMGNYTNGARTCNGCNGTNYTNTCN GARGAR------GAY------AGYAGYAARACNGTNGARAARMGNMGNTAYATGGGNYTN TGYATGCAYMGNCARGCNAAYCARTTYATHCCNTTYCCNTGYYTNMGNGCNGGNMGNATG ATGAARTCNGTNYTNYTNYTNGTNYTNGTNGGNGCNGCNGTNYTNGCNGAYAAYTAYYTN TGY---CCNGAYGAYGGNCARAARTTYGARTGYTTYGARTCNAARCCNGARTAYMGNGCN TGYYTNACNAAYGGNMGN------MGNGARAGYGTNACNTGYTCNAARTGYAARMGNAAR TAYGARTTYTGY------AARACNCAYTTYAGYGARGCNGAYAAYCCNACNAGYGAYTGY GGNGAYGAYTAYGARGAYACNCCNTGYACNAARGCNAAYTCN------------------ YTNGCNATHYTNYTNCARTGYCAYGGNGCNTCNGCNTAYCCNGGNTAYATGGCNMGNATH CCNAAYGGNTAYAGYGTNCCNGAYCCNTGYMGNCCNGGNAARYTNTGGCAYGGNGTNGGN CAYYTNGCNCCNGGNGGNGCNGGNCCNMGNAAYCARTTYGGNAARGAYTTYGCNGARGCN GGNMGNAARTGGACNACNGCNYTNTGYCARGCNGAYTCNGAYGGNGAYAAYATHTCNAAY GGNAAYGARYTNGGNGAYCCNGAYTGYACNTGGGARGCNGGNAARGCNCCNTCNMGNACN TCNGGNATHACNCAYCCNGGNATHAAYAAYGAYAAYCCNAAYTGY--------------- ------------------------------------TAYGTNGGNTTYYTNAARGAYYTN ATGGAYGARATHGCNMGNAARGCNAARTTYACNTAYAGYTTYCARGAYGCNACNAAYGAY AARTAYGGN---GARTTYGTNTCNGGNTGGACNGGNATHATGGGNGAYGTNGTNAGYGGN AARGCNGAYGTNGGNGGNAGYYTNGTNGTNACNCCNACNMGNGARGAYAGYGTNGAYTTY ACNCARCCNTTYATHTCNAAYGGNGTNAAYYTNYTNGTNGGNAARCCNTCNTGGTAYGAY YTNGGNYTNGGNTAYYTNGTNMGNCCNYTNTCNTCNGAYTAYTGGATHATGYTNYTNGTN GTNYTNYTNYTNATHGGNATHGTNTTYTTYATHATHGGNAARTTYAGYCCNTAYGARTGG GGNAAYGTNGCNGCNGAYAARGAYCCNMGNGGNGCNAARAAYAGYTTYACNYTNMGNAAY AGYTAYYTNTTYGCNYTNACNACNYTNTCNTGGCARGGNTTYMGNGARGCNCCNAARTCN YTNTCNGGNMGNATHATGGCNGCNTTYTGGYTNYTNTTYGTNYTNTTYACNYTNATHGCN TAYACNGCNAAYYTNACNGCNTAYTTYATGGCNCARATHCCNAAYYTNAARTTYAARAGY TAYGARGARYTNYTNYTNAAYTCNGARGTNGAYGTNTAYGCNYTNCARTCNGGNTCNACN GARGARTAYYTNMGNACNAGYMGNAGYAARACNYTNMGNAGYYTNTGGTCNAARATGAAY AAYMGNGGNACNTTYGCNMGNTCNGARATHGARGGNATHGCNMGNGTNAARTCNACNGGN AARGAYAAYGTNTTYTTYATGGARTCNAARACNGCNGARTAYGCNAGYCAYGCNGARGAY TGYAAYYTNATGGTNTAYGGNGARACNYTNTTYCCNAGYGCNTCNGCNTTYGCNGTNGCN AARGGNTCNGTNTTYMGNAARAARATHAGYGAYGCNATHGARGARYTNMGNGTNATHGGN TAYATHGAYCARYTNGARAARAARTAYTGGGAYTTYGAYGTNCARTGY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNTTYACNYTNTGYYTNTTYGCNGGNACNACNTAYGCNGTN TTYTAYATHCCNGGNTCNGTNGTNAGYTAYCCNAARATGGGNAARMGNGCNTTYTAYACN AAYGCNACNGGNAAYMGNTAYCCNYTNATGGGNMGNMGNTCNAGYCCNGCNGAYAARMGN GAYACNGARCCNCARGARCCNGCNGTNGGNGCNATGGTNGARGARAGYAAYGARTAYAAY ---------AARMGNGGNGTNTTYACNCARGGNCCNCAYMGNAGYTTYCCNMGNGTNGGN MGNGCNGGN---------------GTNAGYGARTCNCCNYTNAAYACNGTNAGYGGNMGN ATHMGNAGYGARYTNGARGGN---GGNGAYGGNAGYGAYGTNMGNAAYYTNYTNGARGGN CARGGNGARAARCCNGTNGARGAYAAYTCNTAYAAYTCN---CARTTYYTNTTYYTNATH TTYGAYCARGAYGGNGAYAGYCARYTNAGYAARTCNGARTTYTAYGCNGGNGTNGCNAAR ATHGTNGARCARAAYYTNYTNTGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GCNAAYYTNGARCAYGTNTGYAGYCCN AGYCAYTTYGARAAYCARCARATHGGNATHTGYGGNGAYMGNYTNGCNACNTCNGTNCAR TTYATHTGYCARTAYGCNGTNAGYACNGCNMGNTAYYTNGTNAARMGNAGYTAYCCNMGN GAY---------ATHGAYAARGAR---ATHCAYGAYATHATGYTNAAYAARAARGAYGCN YTNTCNTAYYTNACNAARMGNTCNGGNTAYCARGGNATHGTNTGYGARTGYTGYATHAAY TCNTGYTCNYTNAAYGARYTNGTNCARTAYTGYGARCCNCCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY GARTAYAGYAAYGAYGAYGCNGARGAYGCNTCNGCNTAYGGNGARAARMGNAARGGNACN MGNTCNCCNCCNMGNTTYGTNGGNAARMGNGGNGTNCCNMGNTTYGTNGGNAARMGNTTY MGNCCNMGNTTYGTNGGNMGNMGNGGNGCNCCNMGNTTYGTNGGNAARMGNGGNATHCCN MGNTTYGTNGGNAARMGN------------------------GARTCNGAYATHGAYGGN AAYGAYTAYATHTTYCARTGGGARGCNTTYAAYGAYGTNAARMGNAGYGCNCCNMGNTTY GTNGGNAARAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYATGGARATHGCNYTNGAY ACNTCNAAYTAYYTNAAYAARGARYTNAGYTAYGTNCCNTGGGTNGCNGCNAAYMGNGAR YTNGGNTAYGTNGGNMGNATGATHTCNYTNACNTCNACNTAYGGNCCNTTYCARGARTTY ATGAARGARAARTCNGGNCARGCNTTYGCNATHTAYGGNYTNGAYAAYACNGGNGCNTCN CAYGARACNYTNTCNMGNACNACNATHGCNTCNATHGCNTGYGGNTAYGGNGTNGARAAY TGYACNTCNAARGCNATHCARCARTAYAARGCNTGGATGAAYAAYGAYAAYAARATHGAY CCNAAYYTNAARTCNATHATHTAYTGYACNGCNATHGGNGARGGNGGNTGGAARGARTGG GCNTTYGCNYTNAARATGTAYGARATHTCNATHGTNGCNTCNGARCARATHAARYTNYTN GGNGCNATGGCNTGYTCNTCNAARCCNTGGATHYTNAGYCAYTAYYTNAARYTNGTNGTN CARCCNAAYTCNATHMGNAARCARGAYGCNYTNAGYGTNATHGGNAGYATHGGNTCNTCN ACNATHGGNMGNTCNYTNGCNTGGGARTTYTAYMGNGARAAYTTYGAYCARYTNAGYGAY TAYTTYTCNGGNTCNYTNTTYACNTGGGGNMGNYTNGTNGGNACNYTNACNMGNTCNYTN AAYACNGARTTYAARYTNTCNGARYTNAARGCNTTYATGGARACNAAYGCNAAYAARACN GCNCARMGNGCNTTYGAYCARGCNATHGARAARGTNMGNAGYAAYATHAARTGGATGGAY AARAAYTAYCAYGTNGTNACN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GTNCCNCCNGTNCCNGTNGCNCCNGCNCCNGTNTCN ACNTCNGTNCCNGTNCCNGCNCCNCARCCNCCNGTNTCNAAYGCNGTNACNGCNCCNGTN GARACNAARGAYAGYCCNGTNGTNAAYTCNGTNCCNGARGARAAYCCNGCNAAYGAYCAR CARATG------------GAYGARGARGARYTNYTNGARGARAAYGGNACNTCNCARATH GARGARATHGARYTNTCNCARGCNGARGTNTTYACNAAYATHAARAARAGYGGNGGNAAR YTNGTNTAYGAYMGNGCNTAYYTNATHGGNYTNMGNGARTGYGTNTCNTCNCARACNAAR CCNGAYGGNYTNCCNGARYTNGAYATHATHYTNGAYAARCCNAAYCCNGCNYTNTCNMGN ---CARACNGGNGGNCCNGCNGAYTTYACNCCNGCNTTYTTYCAR---ACNGCNACNAAY CARMGNCAYCCNCCNCCNATHGGNAARAGYAGYAGYMGNGGNMGNCARMGNCCNGGNGAY ATGCCNGGNACNACNMGNATHATHAARAGYATHTCNATGTCNAAYGAYAGYAARACNYTN CAYCARAGYGARAAYCCNTGGAAR---------CCNTCNACNAARACNGARAARGAYGAR AARAARACNYTNGAYGGNGARATHYTNTTYATHATGAAYMGNATHACNCCNACNAAYTTY GARAARATGGCNGTNGARATGAARAARYTNGAYGTNAARACNTAYGAYGAYYTNAARTTY ATGGTNAARATHTTYTTYGAYAARGTNACNATHGARACNAARTTYGTNGARGCNTAYGCN CARYTNTGYAARGTNATGTCNGGNYTNAARGTNACNCCNCCNGCNGAYGGNAGYGTNAAR GAYCAYATGGCNACNTTYMGNGTNGTNATGYTNACNAARTGYCARCARGARTTYGARGCN GAYAARGCNATHATHTTYGARGAYCCNGCNGARAARAARAARAARYTNGARGCNGARTAY CCNGARAARACNCCNGARMGNAAYGARAARATHGARGCNATHYTNTAYCARATGAARYTN AARMGNATGAARTTYTAYGGNAAYATHMGNTTYATHGGNGARYTNTTYAARYTNGGNATG YTNACNGARAGYATHATGCAYGAYTGYATHTTYMGNYTNYTNAARGCNMGNGAYGAYGAY TCNYTNGTNTCNYTNTGYAAYYTNYTNACNACNGTNGGNMGNAAYYTNGAYACNGARAAR GCNAARCCNMGNATGGAYCARTAYTTYTCNCARATGGGNAARATHGCNGAYGARMGNAAR TCNMGNATHAARTTYACNYTNMGNGAYGTNATHGARYTNMGNCARAARTGYTGGGTNCCN MGNAARGARATHACNGGNCCNAARAARATHGAYGARGTNCAYAARGAYTTYGCNCARGAR CARGCNMGNAAYCARTTYYTNGCNTCNCARCCNYTNCCNCCNMGNAAYGAYAAYAAYCAR GCNGGNAGYMGNAARGGNAGYMGNCARMGNCARGAYGAYAAYAARGCNAAYGAYGARGGN TGGAAYACNGTNAGYTCN---AARTCNGTNMGNATGATHGAYGCNTCNAARATGAARATH TCNAAR---AAYGTNGTNGAYGAYAAYATHCARYTNGGNCCNGGNGGNGGNATHCAYAAR CARGCNYTNTGGGGNMGNGGNAGYCAYGGNGGNGCNCARTCNTCNTCNCARGAYGAYMGN TCNACNTCNGGNTCNAAYMGNTTYTCNGCNYTNGGNGAYGAY---TCNMGNMGNCCNTTY CCNMGNTCNCCNTCNMGNGGNGARGGNTCNGCNGGNMGNAGYYTNMGNCARGGNCCNACN GCNGGNCAYGGNMGNGGNAARATHATGTCNMGNTCNAGYCARGARGGNGARMGNMGNGAR GCNATHGCNAAYGCNMGNTCNTTYATGGGNGGNMGNTCNCARAAYTCNAGYMGNGAYAAY AGYTGGAAYMGNGAYGAYMGNMGNCAYGTNATGGGNCCNCARAGYTCNGGNGARMGNGAY AAYCCNATGACNMGNAGYGAYAGYGGNGTNMGN---ACNGARGARTTYMGNGCNCCNGCN CCNCCN------GCNGTNAARCARATGTCNGARTCNGARGTNGARACNAARGCNGTNAAY ATHATHGAYGARTAYATHAAYATHMGNGAYYTNGGNGARGCNAARYTNTGYGTNAARGAR YTNACNGGNCARAAYCAYYTNTAYYTNATGGTNACNGCNTGYATGAAYAGYGTNYTNGAR AARMGNGAYGARGCNMGNACNYTNACNGGNAGYTTYTTYCAYGARYTNGTNAGYAGYAAY ATHATHACNGCNAAYATGTAYATHAARGGNYTNAAYGARGTNYTNCARTAYGCNAGYGAY ATGGTNGTNGAYATHCCNACNYTNTGGAAYTGYYTNGCNCARYTNATHTGYCCNYTNYTN ATHGGNGGNTCNYTNCARTGGTCNATGYTNAARCARGCNTGGACNCCNCAYYTNGAYAAY AARGAYGGNGCNAARYTNATGGCNTCNGTNATHTCNCARTGYGTNGARAARCARGGNGAR AARGARGTNGCNCARAARTGGCARAGYAGYGGNYTNAGYTGGTCNAAYTAYYTNAARGGN GAYGARGTNACNACNTTYGTNAAYGAYAARAARYTNGGNTTYACNYTNGGNGGNTCNTCN TCNGCNGGN---------------------------------------------AGYYTN GAYYTNGARAARATGATHMGNAGYMGNGTNCCNAAYAARGAYYTNATHTCNTAYATHGAR AARACNGTNCCNGGNAGYAARACNGAYAAYAGYTTYATHMGNGCNYTNACNACNGCNGTN GTNACNGCNTCNATHACN---------GARAAYAARAAYYTNAAYGARGARGTNATHAAR TTYTAYAARGAYGTNYTNCARAARTAYATH---GGNAAYAARGTNGAYYTNCARYTNCAR GCNYTNTTYGCNATHCARACNYTNATGGCNMGNYTNGARCAYCCNTCNGARGTNYTNCAY AARYTNTTYGARYTNYTNTAYTAYGAYGTNTGYATGGARGARGARGCNTTYTAYAARTGG AARAAYTGYGAYGAYCCNCARGARCARGARTCNAARGGNACNTGYYTNYTNCARGTNMGN CARTTYTTYGTNTGGYTNAGYGARAAYGARGARCCNGAR--------------------- ------------------------------------------------------------ ------------------------------------TGGAAYGTNYTNGAYGARYTNGAY GAYYTNTCN------GGNGAYCCNYTNGGNGAYGAYAGYATGGARGCNTTYATHAAYYTN GAYAARTTYTTYAAYGGNAAYTCNTTYTTYGAYGARGAYGGNAAYYTNATHGTNCCN--- GAYGARAARGARGCNGARGTNAARCCNGTNATHAAYTTYGGNCCNCARCARACNTCNGGN GTNTTYGAYTCNGCNYTNCCNACNTTYATHACNCARACNCARACNATHCARACNACNGAR AARCCNMGNMGNAARMGNTCNGCNMGN---------GGNGCNATHAARACNAGYYTNTAY GARATHCCNGCNGCN------------------------TCNGTNATH------CCNGAR ATHGCNGGNGAYGGNGARYTNGAYCAYGAYTAYAGYTCNAARMGNCARMGNATGTCNTCN ATGCCNGARATHYTNACNTCNACNAGYGGNGCNATGAAR---ACNTCNACNCARGGNMGN AARGAYACNYTNACNTCNTGYTCNGAY---------------------------GTNTTY GAYGAYGAYAAYGAYYTNTCNATGTCNGCNGAYAARCARACNATHMGNMGNATHAARAAY AAYCAYGCNTCNAARMGNTCNMGNGARCARMGNAARCARAARTTYGARGAYATGGAYGTN GARGCNGARGARYTNATHGTNAARAAYCARGARYTNMGNGARAARATHGTNMGNYTNGAR CARYTNGCNAARGARATGAARCARGTNYTNGTNGCNAARATGGCNGGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CCNAARYTNTCN GGNGCNGTNTTYGGNAGYGGNTCN------CAYGAYACNCCNAGYTCNACNTTYAAYTCN TTYAAYTCNTTYCAYATHMGNCCNTCNGTNTTYTCNGGNCCNTTYGAYTCNGGNATHGGN MGNGGNGCNGCNCCNYTNYTNAARCCNGCNAARYTNCCNGAYCCNACNAARTCNTGYGAY TGYAARGCNGAYTCNGCNAGYGARGCNGAR------ATHGCNGCNGCNGCNGCNAARTCN AGYGARGCNACNTCNGTNAGYGARMGNYTNGGNGGNGCNGAYGGNACNTCNGGNGGNAGY GARGTNTCNTCNTCNTCNTCNACNTCNTCNGCNYTNCCNCCNCCNCARTCNYTNCCNTCN GAYGCNGARGGNGCNGTNGCNGGNGARAGYACNCCNTAYAAYCARGAYATHGTNCCNGAY ATHAAYAARAAYAGYMGNYTNAARGAYTCNTCNGGNGTNACNAGYAGYTCNCARTCNTTY GTNTTYGGNMGNAAYYTNTCNCARMGNGTNACNGGNATHTCNTCN---TCNCCNGGNGAR AAYGARGCNTCNGCNTCNTCNGGNTTYGTNTTYGGNGARTCNATGGGNTCNMGNGCNACN GTNGARACNAAYGGNTCNTCNCARTCNCAYGAYGAYGAYGAYAGYGAYTCNGAYTCNGGN AAYAARYTNAAYCARACNYTNGARGARTCNGCNMGNGARTAYCARGCNAARCAYGARAAY AARACNGARYTNAARGTNGTNGAYACNATHACNGGNGARGARGARGARTCNAAYGTNYTN CARGCNAAYGCNAARYTNTTYTTYTTYGARACNAGYAAYGARTCNTGGGTNGARMGNGGN MGNGGNACNATHMGNYTNAAYGAYATGTCNGCNMGNGAYAAYACNAAYTTYCARTCNMGN YTNGTNATGMGNACNCARGGNAGYYTNMGNGTNGTNYTNAAYACNAARATHTGGCCNGGN ATGTCNYTNGARAARGCNTCNACNAARTCNATHMGNATHACNGCNATGGAYACNGAYGAR TCNATHAARGTNTTYYTNATHACNTCNAGYACNAARGAYTCNGARAAYYTNYTNMGNGCN ATHGAYTGGMGNATHCARCARYTNAARATHCARGARGARGTNMGNMGNGAYCARTCNGAY GTNMGNGCNGGNGAYAARMGNMGNGCNGAYGAYTCNGAYTTYGARYTNCCNYTNAARAAY AARAARGTNAAYAGYTCNCCNGAYCARGGNATHTCNATHACNAARAARGARGARTCNGAY AGYAGYGTNCARGAYCCNGARACNGARGCNTCNTGYGARAGYCAYTCNTCNTCNYTNACN ATHAARTCNGARTCNGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AAYCCNAARTGGGAYGARCARTTYATHATHCCNATHGAY GAYGTNAGYAARCCNYTNAAYGTNAARGTNTTYGAYTAYGAYMGNGCNTGGAAYGAYGAY CCNATGGGNAGYGCNGAYYTNGAYYTNTCNACNYTNGARATHGAYAARGARGCNGARYTN AARYTNATGYTNAGYGARMGNGGNAARTCNGAYTAYATGGGNAAYYTNYTNGTNACNTGY AGYYTNGTNCCNAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYGGNTAYAARYTNAAYGTNGARAAYCCNCAYMGNCCNATG AARACNYTNTCNGCNATHATGACNTTYTTYGTNCARACNTCNGGNATHYTNACNACNGCN CCNATGACNTGYAAYAAYYTNCCNAARATHGGNATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGCNTCNTCN AAYYTNTCNMGNACNGTNYTNAARTCNYTNAARGGNMGNTCNTTY---TCNGCNGCNGCN GCNCARGCNGAR---AARGCNCAYGCNGARAGYYTNGAYAARTGYACNGTNAARAARYTN AAYAAYGGNATGYTNGTNGGNACNGTNCCNTCNAARTCNCCNATHGCNMGNATHGCNGTN GTNGCNAAYGCNGGNTCNMGNTTYGARAAYGGNGAYAAYYTNGGNGTNTCNCAYTTYYTN MGNATGTCNTCNMGNYTNMGNACNGARAAYATGTCNAGYYTNGCNGTNACNMGNACNGCN CARCARTTYGGNAGYGAYATHACNATHATGGGNACNMGNGARTAYATHTAYTTYAARAGY AAYGTNACNMGNGAYTGGGCNGAYCARATGGTNAARGTNYTNCARGARYTNACNACNAAY CARACNTAYGTNCCNTGGGARTTYTCNGAYGTNCARAGYGAYGCNGAYGGNATGYTNYTN GAYYTNGCNATHTAYAAYACNMGNCCNCAYATHMGNGCNGTNGARYTNYTNCAYTCNGCN GCNTAYMGNACNACNYTNGGNAAYTCNYTNTAYGCNCCNGAYCAYATGGTNGGNAARTAY TCNCCNGARCARGTNYTNCARTAYGTNAARAGYACNTTYACNGCNGGNMGNATGGCNYTN ATHGGNGTNGGNATGGAYCARGCNCARYTNGARGAYATHGCNTCNGAYTTYAARCCNCAY GAYGGNCARGGNGCNCCNGCNGGNAARGCNACNTAYTTY---GGNGGNGARYTNMGNGAR AAYACNGGNGGNGARGTNTCNTAYGTNGCNGTNGGNTTYGARGCNCCNAGYYTNACNAGY AARGAYYTNYTNGCNTCNGARGTNYTNMGNMGNATHATGGGNACNGGNCCNCAYATHAAR TAYAGYAGYGGNACNGCNACNGCNCAYYTNCCNAARGCNGTNGCNGARGCNACNAGYGGN CCNTTYTTYGTNTCNGCNCARAAYCAYACNTAYACNGAYAGYGGNYTNTTYGGNTTYAAY GCNGTNGCNCAYGCNTCNCARATHGARAARGTNYTNCARGTNGCNGCNGAYAARGTNAAR GGNYTNGGNTCNGGNAGYATHTCNGAYGARGAYGTNACNMGNGGNAARATGCARYTNAAR GCNGARATHTGYATGCARTTYGARAAYCCNGAYGTNYTNYTNAAYTGGYTNGGNGARCAR GCNYTNAAYGGNGGNGARATHGTNACNCCNGARGAYGTNTGYAARATGGTNGAYAGYGTN ACNACNAAYAAYGTNAARACNGTNGCNAARACNATHGTNAGYTCNMGNCCNTCNATHGCN TCNGTNGGNAAYACNGCNAAYGTNCCNTAYYTNGAYAARYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AGYTCNCARGGNGGNAGYCARGARAGYGCNCCNGCNACNCCNTCNGARACNGCN GARACNGGNGCNGCN---------GAYGGNTCNGCNGCNGARACNGGNGARACNGCNGCN CCNAGYCARGARTCNGCNCCNTCNGCNGTNMGNACNGARTTYAARTGGGARAAYGGNGGN GARACNGTNYTNGTNAGYGGNACNTTYAAYAGYTGGCARGARAARATHGCNYTNTCNAAR ACNGGNGAYGTNTTYACNGGNTTYGTNGAYYTNCCNGTNGGNGARTAYYTNTGYAARTTY ATHGTNGAYGARGARTGGGTNGTNAAYAARAAYYTNCCNATHAARGCNGGNGARGAYGGN CARGAYAAYAAYGTNATHYTNGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TAY AAYACNATHMGNMGNGCNTCNGCNACNYTNMGNCAYATGTCNCAYAAYMGNGARACNCCN ATHATGGGNAGYMGNGCNGGN---TCNATGACNYTNGAYAGYTCNTAYMGNMGNACNMGN MGNGGNMGNGARGTNTGYCAYTCNGCNCCNGGNACNYTNCARMGNCARCAYMGNAAYMGN CAYTCNGGNYTNGAR------------------------------------------GAR CARGARGCN---CCNCCNCCNCCNGCNTAYAGYATGCAYTCNGGNGAYGTNTTYTTYGGN TCNGAYTTYYTNTCNCCNGTNGARATGCARTCNAGYGTNCAYTAYGAYGAYAAYCCNGAY CARAAYGGNAGYGGNGCNCARCCNYTNYTNCARCAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TGGMGNACNAARTGYYTNAARYTNGARAARGTNATHAARACN YTNTCNAAYCAYTGYGTNMGNGTNGTNGARAARCAYGARGAYYTNYTNGAYAARTTYAAR AARAAYCARGAYCARTAYAAYACNYTNAARYTNAARTTYAARGAYAARGGNGARCARATH AARAARGCNMGNGAYGTNYTNATHCCNGTNTCNAAYGARYTNAARTCNYTNMGNGARAAR TAYGAYATHGCNGTNMGNTGYCARATGGARGCNGARTCNTTYGCNGTNAARACNACNAAY AARAAYAARGARYTNAARMGNCARAGYCARATGYTNYTNCARAAYCARGGNTCNYTNAAY GTNGTNGARATHAAYTTYGAYGAYYTNGGNCARGARGAYGARGARGARAARGARTAYATH GARAARYTNGGNCARCARATHGAYGARYTNGARGARCARAARAGYACNYTNAGYATHCAR GTNAARGARYTNAGYGARAAYTTYCARGAYGARAARGARACNAAYGGNMGNYTNAARGAR AARAAYGARYTNATGAARGARGARYTNMGNCARGCNMGNGTNGCNYTNAARCARCARGAR GARYTNYTNCARCARGTNGCNACNACNTCNGARAARGCNGTNAARGARTAYGARGAYATG GARCARACNTAYMGNAARGARTAYGTNGTNMGNAAYGARGCNGARMGNGTNGCNCARMGN YTNTTYACNGARMGNGAYCARGCNMGNMGNGARAGYGCNYTNGCNYTNAGYAARGTNGCN GAYAAYAARAARYTNATGGAYGCNATGYTNGARATHCARGARYTNAAYGCNAARACNGCN CARATHAARGARGAYTAYGAYMGNAARATHGGNGARYTNGARAGYCARYTNGARGCNGCN AARGARGTNTTYAAYCCNGARACNYTNGARTCNGARAAYGARGARYTNACNGARGARMGN AAYTCNYTNCARGTNAARGTNGARAARAGYGARTCNGARATHMGNGARYTNCARTCNAAR TAYACNGCNYTNYTNGARACNTAYAARAAYYTNGARACNAARTAYGARAAYGCN---ACN MGNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNATGGCNAARTCNGGNGGN TTYYTNCARMGNATHATHGGNMGNAARGGNCARMGNGARAARGCNAARGARCAYYTNAAR AARGGNGGNGTNACNYTNGAYGAYAAYCAYTCNAARGCNGTNGAYGARATGATGAARMGN ATHMGNAGYGGNAAYATHGGNYTNAARCCNGTNYTNGGNAARACNMGN------GCNCAR TCNYTNCCNGARAAYGAYGARCCNAAYGCNATGAARGARYTNCARGGNYTNYTNACNAAR ATGMGNAARTCNAARAGYGARGAYGAYYTNTCNGTNTTY---GGNGAYACNGGNGTNGAY GARGARTCNGARYTNGGNAARATHYTNAARMGN---MGNCAR---ATG------------ ---------GCNATHCARGARACN------------------AAYTCNTCNCCNCCNCCN ACNGCNMGNCCNGTNCCNYTNCCNMGNAARYTNTCNACNATHCARGAYGARGCNGARGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CARGCNATGGGNTCNYTNTCNGCNTCNGCN YTNTCNGCNACNATHCARCARGTNTCNTCNAARATGAAYGGNCCNATGGTNTCNCARTCN AGYGTNAAYGGNGGNGGNCCNCCNATGGARAAYGTNGGNATHCARMGNTGGTTYAGYTCN GAYATHYTNAARACNCARYTNCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GAYAGYGCNGGNAAYCCNYTNCCNGTNCAR GARAGYTTYAARCCNTCNAAYAARYTNCCNTAYCCNGGNATHYTNTGYGGNTCNTTYTAY MGNGAYGTNYTNMGNCARTGYTTYCCNCARACNYTNATHAGYTCNGTNTTYTGYTTYGAR ATGTTYYTNATGCAYGTNGGNAGYGTNCAYCCNCARTAYATHGCNTCNCAYTGYAARAAR YTNGCNGTNGARYTNTGGGARATGTCNGGNGAYGCNTAYTCNACNYTNAAYYTNTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGNCARAGYGARTCNACNGARAGYAGYAARATGAARMGN TCNGARMGNCAYATGATGMGNYTNAARAGYATHATHGCNAAYGTNYTNAARGARAARGGN GTNACNAARGGNGAYCCNATHTAYGAYGCNTGYTCNAARAAYYTNYTNAAYGTNAGYATH ATHYTNYTNAARACNYTNCCNAAYTCNAARAAYYTNACNGAYGARATGAARTCNGTNGTN TAYGARCARGTNCARCARATHATHAAYYTNGARAARMGNMGNTCNGGNATHGCNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TCNGARAARTCNAGYTCNTCNTCN TCNMGNAARGAYAARAARMGNAARMGNAGYMGNAGYMGNGARMGN--------------- ---MGNMGNTCNMGNAGY---------------------MGNGAYMGNAARTCNAARAGY MGNAGYMGNGARMGNAARMGN---MGNGARAARGAYAARGGNMGNMGNAARAGYMGNAGY MGNAGYMGNGAYAARGAYMGNMGNMGNMGNAGYMGNTCNCCNGGNAARMGNMGNAGYMGN AGYCCNATHMGN---GARMGNYTNCCNGARYTNTCNGTNGARGARMGNGAYGTNMGNACN ATHTTYTGYATGCARYTNTCNGCNMGNATHMGNCCNMGNGAYYTNGARGARTTYTTYTCN TCNGTNGGNAARGTNMGNGAYGTNMGNYTNATHACNGAYAAYAARACNMGNMGNTCNAAR GGNATHTCNTAYGTNGARTTYGCNGAYCCNGARTCNGTNACNYTNGCNATGGGNYTNACN GGNCARAARYTNYTNGGNGTNCCNATHATGGTNCARCCNTCNCARGCNGARAARAAYMGN GCNCARCCNGCNGTNCCNGCNCARGCNCARAARCAR---GCNACNGARGGNCCNYTNMGN YTNTAYGTNGGNTCNYTNCAYTTYAAYATHAAYGARGAYATGYTNMGNGGNATHTTYGAR CCNTTYGGNAARATHGTNGAYATHAARATHATGMGNGAYCAYGAYTCNCARMGNTCNYTN GGNTTYGGNTTYATHAGYTTYGCNAAYGCNGAYGAYGCNAARAARGCNYTNGAYCARYTN AAYGGNTTYGARYTNGCNGGNMGNCCNATGAARGTNGGNCAYGTNACNGARMGNTCNGGN GARGGNGGNCARGGNCCNCARAAY------GGNGTNGGNGGNCARYTNGAYACNGAYGAR ATGGAYMGNGCNGGNATHGAYYTNGGNGCNACNGGNMGNYTNCARYTNATGGCNAARYTN GCNGARGGNACNGGNTTYCARATHCCNCARTAYGCNGCNAGYGCNYTNAAYAAYATHTCN ------------ACNCCNGCNGCNGTNCCNGGNATGCCNGCNACNCCNCAYAAYAAYAAY TTYGGNATGCCNCCNGCNATHCCNACNACNGTNTCNGCNCARCCN------------ACN GCNACNGTNACNAAYGCNCCNCCNATHGCNACNCARTGYTTYATGYTNTCNAAYATGTTY GAYCCNACNTCNGARGCNMGNYTNACNTGGGAYCARGARGTNMGNGAYGAYGTNATHGAY GARTGYAAYAARCAYGGNGGNGTNYTNCAYATHTAYGTNGAYAARAAYTCNCCNCARGGN AAYGTNTAYGTNAARTGYCCNAGYATHTCNGCNGCNGTNGCNTCNGTNAAYTCNYTNCAY GGNMGNTAYTTYGCNGGNMGNGTNATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNGAYATHAARMGNCARAGYGAYGCNYTNACNCCNATHMGNGARATGACNAGYGAR GAYGARGAYGARGTNATHGGNAARAARTTYTCNCARGTNTCNATGAGYCARATHMGNGAR AAYMGNACNAARAAYGARTAYGTNATGGARTCNCAYCCNGTNGGNMGNGGNTGYGARTTY GTNMGNACNGCNTTYAAYGTNGARGGNMGNAGYCCNYTNGTNGCNCAYTTYYTNAAYATG AARGGNYTNACNCARGAYGTNGGNCARAARATHYTNATHCARMGNGTNGARGTNGARGAY YTNCCNGCNYTNGAYGCNACNACNTAYAARAAYGTNATHMGNGARTCNTCNAARACNATH MGNAARYTNGARACNGGNTTYCARGAYATGTAYCARAARAAYTTYAARGARAGYCARAAR TTYATGAARCARCARCARAARATGATGMGNGARCAYATGCAYAARCARTCNGCNYTNYTN GCNAAYGARAARGARGTNAARGTNYTNTGYGAYYTNATHATHYTNGARCARMGNAARAGY CARGAYTCNGTNTCNGCNGGNGCNAGYGCNGCNATHGARGCNGCNYTNATGGCNCARGAR ATHCCNGARGARGARAARATHYTNCCNCCNGAYYTNATHTCNGARGARGARAARMGNGTN CAYGCNGAYTTYTTYGAYGGNMGNCCNCCNAARACNCCNGARMGNTAYYTNAARATHMGN AGYTAYATHGTNGAYTGYTGGATHAARAGYAARCCNGCNTAYYTNAAYAARACNTCNGTN MGNCCNGGNYTNAARAAYTGYGGNGAYGTNAAYTGYATHGGNMGNATHCAYGCNTAYYTN GARTGYATHGGNGCNATHAAYTTYGGNTGYGARCARGCNGCNTAYMGNAAYCCNCAYAAR AAYGTNAAYGGNGGNCCNAAYAGYMGNGCNAARGGNATGAAYAARGAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TGYATHCARTGYTCN CAYGGNMGNTGYACNACNGCNTTYCAYGTNTCNTGYGCNTTYATGGCNGGNATHAARTTY GARATGAGYGAYTGGCCNGTNCCNATHTAYGTNTCNTGYMGNAARCAYYTNACNACNMGN AGYAARGTNGARMGNTCNMGNGAYATGCCNGARYTNGAYATHCAYTGYCCNGCNYTNGCN AARCAYAARAAYAARMGNTTYTAYTGGGCNMGNGTNGTNCAYGTNGAYMGNATGAARYTN TAYGARGTNGAYTTYGAYGAYGGNTCNTTYAGYGARGAYYTNYTNCCNGARGAYATHGAR AGYMGNGAYTGYGTNMGNGAYGGNCCNCCNMGNAARGGNGARCAYGTNYTNATHAARTGG GARGAYGGNAGYYTNTAYGGNGCNACNTTYMGNMGNGTNAAYAAYAARGAYATGTAYACN GTNGARTTYGARGAYGGNTCNYTNTCNCAYGCNMGNMGNGAYGARYTNTGGAGYGARACN GARGARATHCCNGTNCAYATHMGNAAYMGNATGTCNCARGCNACNGARCARMGNTTYGAY ATGTGYGTNGARGAR---GCNCAYGAYGGNMGNMGNAAYAARAARAARGTNAAYTAYYTN MGNATGYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGCCNATHCCNGARATHCARMGNYTN YTNGAYAGYCAYAARTCNYTNTCNTTYGAYGARAAYACNCARAARGTNAARTGYAAYYTN ACNAAYCAYGARATGCCNGCNAAYGTNACNGCNATHGARAGYTAYYTNAAYGGNAARAAR TAYAARMGNYTNTCNGAYYTNGARGCNYTNGAYTAYGARGAYCAYAARAARCAYATHGTN CCNAAYGAYAARAARAARAARGARAAYGARATGTTYTGYMGNYTNACNYTNMGNCAYYTN GARAARACNTCNAARGCNATHCARMGNCAYATHAAYGGNMGNAARTAYAARAAYTCNYTN GCNMGNTGGAAYGARTGYAARAARACNGGNGCNAARTTYATHGCNCAYATHMGNMGNMGN GCNAARGGNCCNGAYGAYTCNGAYAAYGARAGYGTNGTNAGYGCNGARAGY------GGN GARGAYGCNAARGARGAYGARGTNGAYGAYGAYATGAGYGAYYTNTAYCCNGARGCNGAY TTYCARGAR------------GARAAYGAYTCNGGNGAYGGNATGGARGARGARGAY--- ------------------------------------------------------------ ---------------------------------------------ATGACNAGYCCNAGY GAYMGNAARCCNYTNCCNCCNGGNACNATGGGNYTNCCNATHATHGGNGARACNTTYCAR TTYATHMGNAARGGNGCNGCNTTYTAYACNGARAARTTYAARCARTAYGGNAAYATHTTY AARACNAAYATHYTNGGNACNAARACNATHMGNGTNGCNGGNTCNGARAAYYTNAGYACN YTNATHAARMGNGARACNGARCARYTNAGYATGAARTGGCCNACNGTNGTNAAYGTNYTN ATGGGNGCNAARAGYYTNCCNACNGTNGTNGGNCCNGARCAYCCNACNYTNAARAARAAY YTNCARMGNGCNTTYACNCCNATHMGNYTNGCNGAYTAYTTYCCNTGYGTNCARCARCAY ATHMGNGCNCAYTTYCARAARTGGGCNGARGARCAR------------GARATGYTNGCN TTYCCNGCNTGYGARAGYYTNATGGCNGAYATHATGYTNGARYTNGTNYTNGGNTGYAGY AARGARAARGAYGARGAYGGNMGNGTNMGNGCNGCNTTYMGNGAYATHAAYCAYAAYYTN TTYTCNGTNCCNATHAARTTYCCNGGNGGNGGNTTYAGYAARGCNTGYCAYGCNMGNGAR GTNATHYTNGAYTTYGTNCARCARMGNATGTCNGARAAYGGNAGYGARAARGAYCAYGTN AGYATGATGGAYGTNYTNYTNTCNYTNCAY---GGNCARGAYGAYGTNYTNGAYGARGAR CARGTNAARGAYAAYGCNATHGGNYTNYTNATGGCNGGNGCNGCNAGYACNTCNGGNGCN GTNACNTGYYTNYTNYTNYTNYTNGGNACNCAYCCNGAYGTNYTNGARAARGTNMGNGAR GARYTNCARGCNGTNGGNTCNTTYGGNAARGAYGCNGTNACNGAYYTNAGYTAYGAYYTN YTNCARAARYTNGARTAYGTNCAYTGYGTNGARAARGARTCNYTNMGNTAYYTNCCNCCN GTNGGNGGNTGYTTYMGNAARGCNGARAAYGAYATGGARYTNGAYAAYTAYCARATHCCN AARGAYTGGACNGTNYTNTAYAGYATHMGNGAYACNCARGCNYTNGCNTCNAARYTNATH CCNGAYGGNGAYGTNTTYMGNCCNTCNMGNTGGCARGARAARGARCARGGNGGNGGNGGN GGNGAYGGNTTYTCNTGYCARTAYATGCCNTTYGGNTTYGGNCCNMGNATGTGYYTNGGN MGNCARYTNGCNMGNATGATHATGCAYACNTTYATHGTNGARYTNGCNYTNTCNGCNMGN TGGGARGTNATHAAYCCNGAYTGYCCNYTNGTNTAYYTNCCNATHACNAARCCNAGYGAY GAYYTNCCNATHMGNTTYCAYGTNYTNTCNGCNTTYMGNAAYYTNCAYMGNGCNMGNAAR GARGTNTTYGCNGGNGAYGARMGNGCNYTNAAYGARGTNMGNCARMGNATHAAYTCNGAY TTYMGNGARAARYTNGARGARACNGAYACNGCNAARATHGAYGARTCNYTNGTNGTNGCN AAYGAYGTNGCNTAYYTNYTNMGNTCNTCNGTNGTNCARYTNAARCCNAAR------GAY GARGARACNTAYGARATGMGNATHACNAARAAYACNATHYTNCCNAARAAYACNCCNTAY GAYCCNAGYAARGARATGCCNGCNATHMGNMGNAARAARAARTGYTCNGAYTCNGCNGAR TCNACN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TGGAARMGNGAR MGNTGGYTNCAYCAYGCNGGNGCNATHMGNGARTAYATGAARGAYCCNAARGAYAAYGGN ATGCCNMGNGGNCCNGAYGCNAGYCCNYTNTTYTGYCCNGARTGYGAYATHACNGAYAGY CARTAYGAYTCNGCNAGYCCNAAYAGYYTNAGYTGGATHATHTCNCCNTGYGARTCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGMGNGAYAGY CAYMGNATGTTYYTNCARGCNTTYATGTCNAARGGNGTNATGAAYACNAGYGARGTNAAR GAYACNTTYYTNCARAGYAARAAYAARTTYGCNGARCCNTTYGARGCNGAR--------- ------AAYGTNACNGGNCARATHCCNCAYTTYGTNMGNACNATHAAYYTNGCNATHGCN CCNTTYAAYYTNGARATHMGNAARGGNATHCARGARCAYGAYGGNAGYAGYGTNTAYTGY YTNGTNAAYACNGTNGARAGYGTNATHTCNMGNYTNTCNTCNAGYTAYACNCCNAAYGAR YTNGARYTNTTYAARAARGTNATHGARCAYATHGTNGARTCNGAYGAYGGNAARATHGGN TCNMGNATHGCNYTNAAYYTNACNGARAARYTNGARAARMGNATGGGNAARGARGARGCN CARAAYTTYYTNAAYAGYYTNGARGARAARAARTGGATHATGAARGGNGARGAYGGNAAR ATHACNYTNTCNGTNMGNACNATHYTNGARYTNGAYCARTAYYTNCARGARATGTAYCCN GCNYTNATHAARAARTGYAAYATHTGYAAYATGATHTCNYTNCARGGNGARTCNTGYGGN MGNTGYGGNATHAARATHCAYTAYMGNTGYTCNGARAARYTNTTYTCNAARCARACN--- GARMGNAARTGYCCNGTNCCNAAYTGYMGNGCNCCNTGGGGN------GARATHMGNATH AARCAYTAYAARMGNCARAARTCNACNTAYGTNAAYCARCARTGYTGYMGNYTNYTNTTY CARYTNAARGTNTCNTTYTTYGGNMGNGAYTGGGARATGAARGCNAARTCNYTNCCNTTY TTYTGYTAYTCNGGNTCNACNCARYTNYTNGARYTNACNGGNACNMGNYTNTGGTAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNATHAAYGTNCAYATGMGNMGNGAYCCNAAR AARGGNGTNGTNAAYAAYCARATHYTNGAYTGGTCNTTYAARYTNGAYGGNATHTTYAGY AAYGCNGAYCARGARGTNGTNTAYAAYACNGTNGCNGCNGAYATHGTNTCNGGNTCNGTN GARGGNTAYAAYGGNACNYTNATGTGYTAYGGNCARACNGGNGCNGGNAARACNTTYACN ATG--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATHGARTCNACNTTYGARTGGGAYATHCCNCAY TAYTCNGARAARYTNGARATGGARMGNACNGGNAARCARCAYTGYACNGTNTCNGAYYTN TTYGARATHGGNCAYCCNGGNTAYYTNGGNMGNYTNGARATHTAYYTNAAYGGNAAYGGN ACNGGNMGNAAYAARTGYATGTCNTTYTTYYTNMGNATHACNAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY GCNTTYACNAAYAARGCNYTNAGYGGNAAYCCNGCNGCNATHTGYYTNGTNCCNCCNGAR ATHGTNYTNTCNGAYGAYGARATGCARAARATHGGNGCNGARATGAAYYTNTCNGARACN GCNTTYYTNCAYGTNYTNGAYAARGAYYTNAAYTTYACNTCNGGNMGNCARTTYTCNYTN MGNTGGTTYACNCCNACNACNGARGTNAAYYTNTGYGGNCAYGCNACNYTNGCNTCNGCN GCNGTNATHTAYGAYACNGCNGGNAAYGARAAYAGYGTNATHGAYTTYGARACNMGNAGY GGNAARYTNTCNGTNACNMGNCAYCCNGAYAARCCNGGNTTYYTNACNATGGAYTTYCCN AARAAYGARCCNGTNTCNYTNGAYTCNGGNAARYTNGARAARYTNYTNCARAGYTGYGTN AARGAYYTNGAYTCNATHCARGARGTNCARTAYTCN---TCNACNACNAARAARYTNGTN GTNMGNYTNAARGAYCAYATHCARMGNCARGARYTNGARAAYYTNTGYCCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGGGNAAYAAYCCNAARAARCARTCNAAR TCNTTYAARGTNYTNCARTGGATGACNGARACNGARAARGAYGARGARGGNGCNGARGAY GAYACNGGNAAYGGNAAYGAYTCNAARCCNAARCCNMGNMGNTCNAARGAYCCNGAYYTN MGNCAYAAYGCNGAYGAYGAYGARATGMGNTTYTCNGGNYTNCAYTCNAARGCNGAYATH CCNTCNAARACNTTYGAYMGNYTNAAR------------------MGNTCNACNCCNAAY GARAAYGGNCARGAYTCNCCNCCNGTNGARGAYGAYACNGAYGCNGTNGGNAAYTAYAAY GARGCNTCNATHMGNTAYACNGGNAARAAYATHCCNTCNCCNGCNTTYMGNGTNYTNCAR ACNTGGGCNGARCAYGAYCCNGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TTYGGNTTYCARAARCARYTNCARGCNTAYGAYTCNGARCAYGTNGTNGAR GARMGNAARAARTTYAARAARAARTTYCCNGAYAAYCCNTTYAAYGAYGARGARGARTGY MGNTAYAAYATGCAYTGYTAYCARCARTTYATHYTNACNGGNACNACNCCNACNMGNTCN AAYGAYYTNTAYCCNYTNCCNTAYAARGCNTAYCAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GTNTCNMGNACNACNAARCARGCNGGNGARGCNGAYGCNGTN GGNATGGTNGCNGTNTTYYTNGAYCCNGTNACNGAYYTNMGNAGYATHATHYTNATHMGN CARTAYMGNCCNCCNATGGARACNTAYACNATHGARTTYCCNGCNGGNYTNATHGAYGCN GCNGARACNGCNAGYCARGCNGCNATHMGNGARATGAARGARGARACNGGNTAYGAYGTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CARTCNTCNMGNGCNAGYAGY MGNTAYTTYTAYCARAAYMGNYTNACNAAYCAYTCNCARTGGGARTAYCCNGAR------ ---GAYGGNGGNGARTCNAARGGNAARGCNGARGAYAARGARGCNGTNGTNCARAARAAR MGNMGNAGYAARGARGARGARMGNGARGARGTNAARAGYMGNAGYAGYMGNCAYMGNAGY AARAARACNCARGAYAARGAYMGN------------------AGYAARMGNGAYMGNCAY AGY---AGYGCNCAYCAYCAYMGNAARAARAARMGNMGNMGNMGNGAYCAYAGYAGYAGY AGY---AGYAGYAGYGARGAYGARAGYAGYCARTCNMGNCAYMGNCAYMGNAGYAARMGN AARAARMGNTCNAARTCNGAYAARTCNCCNAGYYTNGARGTNATHGGNGARYTNGAYGTN ATHGARGAYAGYCCNCCNCCNTCNTCNCAYCAYYTNGCNGGNTCNGARGCNTCNGCNYTN GGNGTNGARAGYGARGGNACNAGYCAYAARGAYCCNTCNCAYGGNCCNCCNTCNCCNCCN TCNATHYTNGTNGCNGAYTAYGGNGARGARGGNGARGTNGARGAYGARAARATGAARGAR CARGCNAAYCCNGAYGTNTCNGCNGAYGTNGCNGARGCNGARGGNGGNGARTCNYTNGAY GGNGARGARATGGARAARGARGGNGGNGCNGARGARGAR------------GARGARGTN ---AAYACNGCNGTNATHATHMGNGCNCCNCARATHATHGTNCCNCCNTAYGTNGCNGCN ATGAAYCARCCNCARATGTAYACNGCNCCNGCNTTY---CCNTCNGCNTCNATHTCNTCN TCNCCNCCNGCNGTNCARGAYAARGARGGNGARACNACNCARACNTCNGARGAYGTNGAY AARGGNAGYAARAARAARAARAARGAYAARGGNGGNAARGARAARTCNYTNTCNGCNAAY TCNAGYATHATGATGAARAARAARMGNGTNTCNTCNATGGTNCARAARTGGCARCARGTN AARAARGARGTNGARAARGARGAYMGNGCNAARGARYTNMGNCARGCNGCNATHMGNGAR AARATHAAYCARYTNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARAARGTNCCNCCNGGNATHGAYATHTTY CCNATHTCNGCNTTYAARYTNGAYAGYACNTTYTAYGTNGARCCNCCNCCNGTNAGYMGN CARTCNAARGAYATHTAYACNGCNTAYGTNAAYMGNGGNTAYCARGGNGCNCARACNGTN TCNGAYGARAAYMGNCAYGCNTAYATHMGNTAYMGNGARGARATGYTNGCNYTNTAYAAY GARAAYTAYAGYCCNCCNGAYCARYTNMGNAARCAYCAYATHATHTTYTCNAAYGARAAY YTNMGNCCNATHTCNATGACNCCNTTYTCNGARGAYGARCARMGNYTNATGTCNCARGGN ATHAAYAGYCAYGTNGTNYTNMGNGGNGGNMGNGGNGGNATHTCNGAYMGNGGNMGNGGN MGNGGNMGNGGNMGNGGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MGNGCNAAY TAYTTYTAYTGYGTNMGNGTNACNGAYCCNGAYGTNCAYAARAAYATHGARAARGCNYTN GARTGGATHATHGAYAARGARCCNACNTTYGGNAAYTTYTGYTAYACNAARGARATGYTN CAYGTNACNYTNTGYGARGTNTCNYTNCARAAYGARGAYGARATHGCNGTNGCNTCNAAR GTNYTNCARGAYTAYCARTCNAAYYTNMGNAARATHACNCCNACNACNCCNYTNTGYTTY MGNGGNYTNTCNGAYTTYCAYGARAARGTNATGATHGCNAARGTNGARCAYGGNAAYGAY YTNATHACNTTYGCNGARATGYTNACNGCNTGGGCNAARGAYGCNGGNGTNAARGTNGTN CARAAYCAYGAYTTYAAYCCNCAYATGACNATHYTNAARGTN------------------ ------AARTTYAAYTAYCARGARCARMGNAARCARYTNGCNGARGARMGNMGNMGNGAR TAYAAYGARYTNYTNCARACNAARACNCARACNMGNAAYCCNCARMGNGARCARGARATH GAYAAYCCNTCNATHATHCCNTTYAAYMGNGTNGARCARGARAARATGAARACNMGNATH ATGGARGARGARMGNCARMGNGARTAYAAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TGY AAYAARGCNAAYGARGARTAYGTNGARGARAAYTAYCARAARGCNATHGAYYTNTAYACN GARGCNYTNGCNYTNGAYGARGCNMGNGAYGAYATHTAYAGYCAYMGNGCNCARGCNCAY YTNTCNYTNGGNAAYACNTCNGCNGCNATHAARGAYTGYGAYGARGCNATHMGNYTNAAY AARAAYAAYCARAARGCNTAYATHAARAARGGNTCNATHYTNYTNAARATHGAYGAYGTN YTNCARGCNCARAAYGTNTTYAARGARGGNCAR---CARYTNTGYGGNGAYAARGAYTTY GARGAYTGGYTNAGYAARGTNGARAAYMGNATG---------AARGARYTNGGNATHAGY CARCARATHCARGTNCCN------------------------------ACNYTNAARTAY AAYTGGTAYCARACNCAYACNCAYGTNATHGTNACNGTNYTNATGAARAAYGTNAARAAR GARGARYTNACNYTNAAYGTNGARGARMGNTCNYTNGGNATHACNYTNAARMGNGGNGAY CARACNAGY---GAYYTNAAYGTNATHYTNGCNCAYCCNATHATHGCNGARCARACNCAR TCNAARYTNYTNTCNACNAARATHGARATHAARYTNAARAARCARGARGGNATHCARTGG GTNAARYTNGARGGNGAYCCNGAYGARATHGAR---ACNACNATHYTNGCNCCNTGYGCN GCNCCNCARGAYACNGARGCNCCNMGNTAYCCNAGYTCNTCNCAYTAYACNMGNGAYTGG GAYAARYTNGCNGCNGARGTNACNGARGARGARAARAAYGARAARYTNGARGGNGAYGCN GCNYTNAAYCARTTYTTYCARAARATHTAYTCNGAYGCNTCNGAYGAYACNAARAARGCN ATGATGAARTCNTTYTCNGARTCNGGNGGNACNGTNYTNAGYACNAAYTGGTCNGARGTN GGNGCNAARCARGTNGAYGTNAARCCNCCNGAYGGNATGGARTAYAARAARTGGGARTTY ATHAAYATGCCNAARMGNAARGCNACNGCNGTNGCNGAYTCNCCNAARAARACNAARGTN GARCCNAARGTNGCNGARTCNCCNCARAARGCN------AARGCNGARCCNGCNAARGCN CCNGCNAARAARGGNMGNGGNMGNCCNACNYTNTCNGAYGARGARMGNGCNAARMGNGCN ---GCNGCNAARGCNTCNACNGGNMGNGGNMGNGGNMGNCCNAARGGNTCNACNAARAAR TCNAARTCNAARAARGTNATHTGYGAYMGNATHAARTCNGGNAGYATHAARMGNAARGAY ATHTTYATHACNTCNAARGTNCCNMGNAAYAGYYTNMGNGARAARGAYGTNATHGCNTGY GCNCARAARTCNYTNGARGARYTNAARATGTCNTCNYTNGAYATGYTNYTNATHCAYAGY CCNTGG------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATHGTNACNGARTAY YTNMGNAARCARCAYGCNYTNTGYCCNCARCCNATHTCNACNTGYCCNACNATGTCNYTN TTYATGCCNCAYCARTGYCCNGARCCNYTNGGNAARGAYAGYGCNTCNYTNTCNATHACN AGYMGNATGTTYGAYMGNCARYTNYTNCCNCCNCAYGGNGGNCCNAAYGGNCARMGNYTN AAYMGNMGNTAYYTNCAYAGYCARATGTCNYTNYTNGCNAAYTAYMGNGAYACNTCNGGN GAYGGNYTNGCNTGYTGYGCNTTYGAYTGYGCNGARGAYACNATHTTYATGGGNTCNTTY GCNGGNGARYTNMGNGCNATGCCNATHGCNTCNTCNAAYGAYGAYTTYGTNAGYACNGTN TGYCAYTCNTCNCCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYGARGAYMGNGTNAAR YTNGAYGAYYTNATGGCNGCNAGYACNACNATHAGYTTYGGNTCNAARCARCAYGCNATG TCNGAYGARGAYATHAARACNAARGCNAARAARAARMGNGCNATGTCNYTNTCNYTNTTY CARCCNGAYYTNGTNCARACNGAYCCNAARAARGAYGAYMGNGAYACNGCNTTYGCNCAR CARTAYTTYAAYCARGTNAARGARACNYTNTCNTCNGAYCCNGAYMGNTTYTAYAARTTY YTNTCNYTNYTNAARGAYYTNAAYAARGAYCAYACNAGYCCNGTNGARYTNTAYYTNGAY ATGGTNTCNYTNYTNTCNGAYCAYCAYCARYTNGTNGARGAYTTYTCNGGNTTYYTNYTN TCNTTYCARGCNYTNGARTGYCARTGYTTYTCNACNAAYTTYCARTAYGCNCARATHMGN CARTTYYTNMGNCARGTNGARACNCAYTGYGGNGCNTCNGCNAAY---ACNTAYCAYAAR GTNYTNMGNGCNATGTCNACNTGGTCNAAYATGTGYCARGARGGNAARYTNGARGGNAAY YTNMGNGAYAARATGYTNGCNATHYTNAARAAYGTNCCNGGNGTNYTNGAYAAYYTNATH AGYTAYTTYYTNGAYGGNGTNGTNACNAAYTGYCAYMGNATHGAYTTYGARGAYGTNTGY YTNGAYGARGARATGGAR---------GARGCNGAYGARTTYGARTGYGTNGTNYTNCCN AAYGARMGNGARGAYTAYAAYACNAARAGYTGYTCNTGYCARTGYCAY---AGYAAYCCN CARGAYGARMGNTTYTAYMGNMGNATHAARCAYTGYATHTCNTGYAGYYTNCARATGTAY GARGGNCARCCNGTNYTNAARATGTCNMGNAAYGARTAYMGNCCNATGTCNATHATHTAY CCNTCNGAYGARCARGARGARAARGARAARATHGCNAARGCNAARAARGARGCNGCNCAR ATHGCNYTNGCNAARGCNAARGTNCARCARCARCARAARGGNAARAARMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AARMGN TGYAARYTNTTYTAYCARAARGARGGNCARTGGGTNGARAARGGNGTNGGNAAYGTNCAY ATHAARCCNATHGARGARTCNAARACNCARYTNYTNATHMGNGCNGAYACNAAYYTNGGN AAYATHYTNYTNAAYATHATGYTNTCNTCNGGNYTNCCNACNTCNMGNCARGGNAARAAY AAYGTNATGYTNGTNTGYACNCCNAAYCCNYTNATG---AARGAYGGNAARGAYGARGAY CARACN------CCNATHCCNATGYTNATHMGNGTNAARACNGGNGAYGARGCNGAYGAR YTNYTNTCNACNYTNGARGARMGNAARGCNYTNYTN------------------------ ------------------------------------------GARGCNGCNMGNGARAAY GCNYTNAARAAYMGNGGNTCNGTNGGNGARACNATGGGNGGNTAYGCNAAYCCNGTNCAR GAYMGNACNGTNCAYCCNMGNGGNGTNMGNCCNGARGCNCARTCNAAYGCNTCNGGNAAY ATGGGNGGNAAYATGAARACNYTNATGGARAAYTAYGGNAAYYTNACNGTNGCNCCNAAR CCNGARCCNAARGTNAARGGNTTYGARGCNCARGARTAYAARGARMGNGARCARGGNAGY ACNAARYTNYTNYTNAAYCAYTAYAGYACNGAYCCNATHCCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GGNTGGCCNGAYGARATG------GAR GCNCCNTGYACNCARYTNACNCARACNAGYACNGAYGTNYTNAAYGAYMGNYTNATGACN TTYYTNMGNGGNAAYCCNAARATHTAYGARMGNATHYTNATGTAYGARCCNYTNGARYTN GAYGTNYTNAARAARCARATHTCNGAYGGNGGNATHMGNATHGGNYTNGCNMGNYTNCAR GAYTTYYTNGAYGARMGNTAYATHACNTTYTCNATGAARAAYATGAGYAAYMGNAAYAAY MGNTAYCCNCCNCCNMGNAARGCNGCNATGAARMGNAAYTCNCCNYTNAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TGG TAYGGNYTNATHCARAAYMGNTGGMGNGGNCAYGTNGARMGNAARTGYCARTCNCARGCN CARAGYATGTGYYTNGARYTNACNAAYGAYTAYGARGCNAARATHTGYGCNYTNAAYGCN AARATHTCNTCNYTNGARGGNACNGTNTCNACNYTNCARGCNGARMGNGARATGTAYTCN GARCARGTNAARAARGCNTTYATGMGNGGNATGTGYGCNYTNAAYATGGARACNATGTCN GTNTTY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNCARTAYCARATHCCN GTNCARACNTCNGCNGCNCARTAYACNGCNGCNCCNGCNAGYATGGCNAGYGGNGGNTCN GTNATHGTNYTNCARCCNTCNGGNGCNATGGCNGGNTCNGTNACNMGNCARCARGGNGTN AGYCARGCNCCNAGYATGACNAAYAARATHATHACNGTNAAYACNAAYGCNTCNAAYGTN GCNCAY---------------CCNGTNGCNYTNCAYATGGCNGGNGARYTNCCNMGNGTN ATHACNACNGCNTCNACNTCNAAYCARCARTCN---------TCNGGNAAYAARAARCCN AGYYTNAARGTNGTNATHCCNGAYMGNGGNCCNGCNGTNAGYTCNGGNAARAAYCAR--- GGNACNGCNYTNGAYACNCCNAAYGTNTCNATHGCNACNCCNAAY--------------- ---AGYCARATHCARGCNATHYTNCARTCNGGNGAYYTNYTNAAYAGYGCNGAYATGGCN GGNYTNTCNCCNYTNGTNTAYCARYTNACNAAYCARGGNCAYGGNCCNGGNCCNYTNACN GCNGCNYTNCARGCNTCNGGNGTNTTYACNCCNGGNGGNTCNYTNTCNATGTCNACNACN CCNATH---------ATHACNYTNCCNGCNCARAARCARGARYTNGTNAARCARGAR--- CCNGGNTCNCCNCAYAARCAYGAYAAYGCNGCNGCNGAYMGNTCN--------------- ---------------------------------------------------ATGAGYTCN AGYGAYTGYTAYAARTGYGGNGTNMGNGGNCAYTTYGCNMGNGAYTGYMGNAAYTCNATH GGNGGNGGNCCNGGNGGNGGN---------------------------------GGNTTY ACNACNTCNCARAARTGYTAYAARTGYAGYMGNGTNGGNCAYTTYGCNMGNGARTGYCCN CARGAYGARGARMGNTGYTAYAARTGYAAYGGNTTYGGNCAYATHGCNAARGAYTGYGAR AARGCNATHTCN---ACNGGNGCNTGYTAYAAYTGYGGNAGYAGYGAYCAYYTNCARMGN GAYTGYCCNCARGCNATHGTNAARACNTGYTAYMGNTGYGGNCARTCNGGNCAYYTNGCN AARGAYTGYGGNGCNGAYATHGCN------------ACNAARGCNTTYGTNGAYGAYMGN AARTGYTAYACNTGYGGNGGNATHGGNCAYYTNGCNAARGAYTGYCCNACNCCN------ ------MGNAARGARTGYTAYMGNTGYAAYCARACNGGNCAYYTNCARAARGAYTGYCCN ACNGGN------TCNGAYACNCARTGYTAYAAYTGYAAYGGNAARGGNCAYATGGCNMGN GAYTGYACNGCNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYATHTAYGGN---ACNGCNGGNAGYAAYGAYGAYCCNTAYGCNGCN ACNGGNCCNCARTTYYTNCCNCARAAYTCNTGGGTNCCNAARCAYTAYYTNGARAARGTN GTNGCNATHTAYGAYTAYCARGCNAAYAARGGNGAYGARYTNTCNTTYGCNGARAAYGCN ATHGTNTAYGTNATHCAYAARAAYGAYGAYGGNTGGTGGGARGGNGTNATGGAYGGNAAR ACNGGNYTNTTYCCNTAYAAYTAYGTNGARCCNTGYATG--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CAYGTNCCNGAYGARYTNAAYCCNGAYTAYGARMGNATHCCNYTN ATHGARYTNCCNGTNGARMGNCCNGARACNCCNGARGGNGCNMGNAGYGARACNGCNCAR TCNCCNATHGAYGAYGCNAARTCNGAYMGNTCNGCNTCNGCNMGNTCNAARTCNCCNMGN GGNGGNMGNMGNTCNAARTCNCCNAARGAYMGNGCNAARTCNCCNAARGGNTCNMGNTCN TCNMGNACNGCNTCNGGNAARAARAARGGNAARGGNGGNAARGARACNCCNCARCCNGAR GCNCCNAARTCNTCNGARGGNATHGGNMGNMGNATHATH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNGCNGTNGTNGCNMGN MGNYTNMGNCCNYTNGCNATHGGNTTYTTYMGNAARACNGGNAAYYTNAAYYTNCAYACN AGYTCNMGNAARTCNGGNGARGCNYTNTAYMGNGARAARATH------TTYGARTAYAAR GARCCNMGNTTYATHCAYCAYGCNGGNACNGCNTTYAGYGCNTTYYTNTGGTAYTGGATH YTNTAYCAYTGYTAYTTYGARTTYGARCAYYTNGTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ACNCAYATHGAYAAYTAYAARTTY GTNCARAAYYTNYTNTCNCARACNGGNGCNTCNCAYAARMGNTTYGARGGNTTYGARCCN GAYATHTTYYTNAAYATHAARCARCCNTTYYTNGAYGCNGTNAARGTNACNYTNGGNGAY MGNTAYACNGARAAYATGCARAAYATHTAYACNATHGCNATHAAYTTYYTNGTNGAYACN ATGGTNGARGGNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATHCARGCNAGYGGNYTNAAYACNATGGARGAYGAYGCNTGYGCNAARYTNTTYATHAAR GCNTCNGGNCARTTYAAYYTNAGYAAYTTYAARGGNGAYYTNTTYCCNGTNATGGAYGGN GAYAAYGARYTNAAYGARATGGTNCARCCNYTNGTNAAYATGCCNMGNTCNYTNYTNGAR CARTGYMGNAARMGNGTN------------------------------------------ ------------------------------------------------------------ ------------------YTNGGNCAYGCNTAYGTNCARMGNTTYYTNGARGARGGNGCN AAYGTNTTYTAYGGNGAYGTNAAYGARACNGTNGGNMGNTCNACNGARGCNGARTTYGTN AGYAARTTYGGNAARGAYMGNGTNGTNTTYTTYCCNTTYGAYGTNACNGAYGGNGAYAAR TTYAARGARGCNTTYGAYAARGCNGTNTCNAARTTYGGNCAYATHGAYGTNATGATHAAY AAYGCNGGNGTNATGAAYGARGGNATHTGGAAYAARATGATHCARATHAAYTGYAAYGCN YTNGTNCARGGNACNATGYTNGCNATGGAYCAYATGMGNAARGAYAARGGNGGNAARGGN GGNMGNATHATHAAYNNNAGYTCNNNNNNNGGNYTNAAYNNNCAYCCNNNNNNNCCNGTN TAYNNNGGNACNAARCAYTTYGTNMGNNNNTAYTCNTCNTCNATHGCNATGACNCCNGGN NNNGARTCNGANATGGGNATHGANATHGCNNNNYTNTGYCCNNNNNNNACNGAYACNNNN YTNATNNNNAANYTNGAYNNNTCNAARTTYYTN---------TAYTCNGARGARTCN--- AARMGNTAYYTNGAYGARMGNTGYAAYCCNGTNTCNCAYGTNGTNGAYGGNYTNTTYTCN YTNYTNCAYAARGARAAR---GTNAAYGGNGCNATHYTNGCNTCNACNAARGAYGGNAAY TCNTTYAARAARATGAARAGYGARGAYYTNGGNACNGARTGGCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GCNATHAGYGAR ATHGCNCCNGCNATHGCNGCNGGNGCNGTNGCNYTNTTYATGYTNYTNATHGTNATHGTN GTNATHGTNTGGGCNGCNTCNTCNAAYACNTTYACNAARGGNTCNATGAARMGNGAYGGN AARGTNAARATGCCNMGNTGGTAYTTYGAYAARAARAARGARATGCARMGNMGNYTNYTN GCNACNACNGCNTCNYTNAARCCNACNCCNYTNGCNAAYGGNAGYCCNCCNGTNGTNCCN GTN---------------GCNGAYAARGARTCNATGGTNMGNGGNTGGAAYMGNGAYACN MGN---------AARATHTAYGARGARAARGGNTAYACNATGGARYTNGGNAAYGARCAR GAYGAYGARTTYGTNATHGARACNACNYTNGTNGAYAAYGARGTNYTNGAYGTNGGNCCN TAYMGNAARYTNGGNTCN---ACNACNGCNACNCCNGTNGARGGNAAYGTNTAYAAYAAR CCNTAYATHTAYAGYAGYAAYGAYMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CAYATHAGY TAYATGAARATGYTNAARGCNGCNAGYTAYYTNAARGAYCCNGAYTGYYTNTTYATHGGN ACNAAYGARGAYGGNTGYYTNCCNYTNAARTCNAAYYTNGTNATHCCNGGNACNGGNTGY ATGGTNGCNCCNGTNAGYGTNGCNACNGARMGNAARCCNATHATHATGGGNAARCCNGAR GTNGGNATGTTYGARGTNYTNMGNGAYYTNCAYCARGTNGAYCCNTCNMGNAGYYTNATG GTNGGNGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GARGAYYTNACNATHCCNGARTAYAAYGCN GARACNCCNGTNGGNYTNGAYTAYGTNATHCCNGTNACNGGNTAYTTYTGYAARYTNTGY CAYAARTTYTAYAAYAARAARTCNGCNAARGCNACNCAYTGYCARACNYTNCCNCAYTAY GGNAARTTYAARGARGCNATGGARGTNAARGTNGCNGCNMGNGARAARAARAARGARGAR GARMGNYTNMGNMGNGARAARGAR---GCNGARGARGCNATGGARGARGGNGAYGTNGAY GARGGNAARGAYGGNGARGARGGNCARGAYGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARATHGGNGGNYTN CCNGTNTGGATGTCNAAYTCNAARGAYATHGGNATHCCNCARTGYAAYGGNTGYGCNGTN GAYATGACNYTNGGNGTNCARYTNTAYTGYCCNYTNGGNAAYTCNGCNTTYCAYMGNTGY YTNTAYYTNTTYGTNTGYTCNTCNCCNGGNTGYCCNMGNYTNAAYTGYTGGMGNGTNTTY MGNAGYGTNYTNTAYGAYGARACNTAYTCNACNGARAARGARGTNCCNGCNAARGARTTY AAYGAYGAYATGTGGACNGAYGGNCARGAYGAYTGGGGNGAYTCNGAYGARGARTGGGGN GARGARGAYGTNAAYATGCCNAARGTNYTNGAYCAYYTNGCNGTNYTNAAYATHCCNTCN GGNYTNGAYCCNTGYGCNTCNMGNTGYCCNYTNGTNYTNAARCCNTAYTAYYTNACNGTN TTYGAYGAYACNCARCCNTCNCAYCAYTCNACNGAYGAY---GGNCAYATHGCNAAYYTN ATHAARGAYTAYGARAARYTNGARGGNMGNCARYTNCARGAYYTNATHACNGAYTCNAAR GCNAARGGNAARGGNTCNTCNTCNGARAGYTAYGARAARGCNAAYATHAARCAYGGNGAY AARATHTTYCAYAARTTYYTNAARGTNYTNCARAARTTYCCNGARCARTGYGTNMGNTAY GAYMGNTGYGGNCARCCNYTNYTNGTNCARGGNYTNAGYCCNGTNGARTCNGTNGTNCCN GTNTGYACNMGNTGYGGNTGYGTNMGNGTNTTYGARYTNCARYTNGTNCCNGCNYTNATH CCNTGGYTNMGNTCNCAYCARGGNGAYTCNTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNATHGTN AARGTNTTYATHGARCARGGNYTNYTNGAYTTYATHCAYGGNYTNAARYTNTCNGTNATH AARGARTTYGGNAGYATHTCNYTNAARGARCARYTNGGNYTNGAYAAYYTNGCNTCNATH ATHGGNCAYATHMGNGARMGNGTNGARTGYGGNGTNGAYAARTCNACNATHTCNYTNTAY CCNTAYYTNATHAARAGYGARCARGTNGCNGTNTCNGAYTCNAARAGYGTNATHGAYCCN GAYGAYGARYTNTAYGARMGNYTNATHGCNGAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AAYYTNATHGARYTN GTNAARCAYAAYCCNCCNYTNTAYGAYCCNTCNGARGARTAYAARGAYCAYATHYTNCAY MGNCAYATHTGGAARAARATHGCNCARGARATGAAYGARACNGAYATGACNTGGAARGAY TGGAARAARGTNTGGMGNYTNAARMGNGAYGARTTYACNMGNAARMGNMGNGARATHACN AARCAR---CCNACNGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGGCNGCNGCNGGNYTN AGYYTNGARAAYCCNGTNTTYAARGCNTTYYTNTTYTAYGCNGGNATHATHYTNATHAAR ACNATHTTYATGTCNYTNATHACNGTNTTYTAYMGNGTNACNMGNAARGTNTAYGTNACN GARAARGAYGCNATHTTYTTYACNCARAAYAARAARAAY------TGYAARGTN---GAY ---CCNATHGTNGARACNGTNMGNMGNGCNCARYTNAAYGAYYTNGARAAYATHATHCCN TTYACNYTNYTNGGNYTNYTNTAYTCNACNATHGAYCCNAAYYTNTCNYTNGCNATHYTN CAYTTYCARATHTTYACNATHGCNMGNATHYTNTAYACNATHTTYTAYYTNTTYTCNGCN CCNTCNCCNTCNMGNGCNGTNGTNTTYAGYGTNGGNATHTGYGTNAAYYTNTCNYTNGCN GTNCARGTNATHTGGCAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TAYTCNGGNAARCAYAAYGGNATHTAYATHTAYYTNAGYMGNATH YTNMGNCCNTTYTGGGAYAGYCCNGTNACNACNGARTTYGTNCAYGAYACNAARCARGGN MGNGTNACNTAYYTNACNTCNAAYTTYAGYGTNGARGARYTNTGYMGNGCNYTNGARATG GTNMGNGAYYTNYTNGAYTTYGTNGAYTTYAAYTCNAARTTYGGNGTNGAYTCNCAYGTN GAYATHATGAGYGCNGGNMGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNAARGAYTTYCAYGTNCCNATHACNATHGCNAARGGNMGNGARAARGTNMGNGARATG TTYYTNAARAAYAARCAYGTNACNGAYATHMGNGTNATGGAYATGYTNGTNATHAARGGN CARATGGARYTNGTNGARACNGCNAAYATHTGGAARCARMGNCAYCAYGTNATGATGTAY TTYAAYGAYACNGTNAAYCCNAARCCNACNGAYTTYYTNAGYAARTTYTAYGARGGNCAR GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARYTNAARGTNTAYAARGGNGTNGARMGNTGYTGGCARTGYTCNATGGAYYTN GARAAYTCNACNYTNMGNCARAGYYTNGAYYTNATHTTYAAYTTYYTNGCNAARTTYCAR YTNATGAAYYTNACNTAYACNGARGGNGTNATHYTNCARGCNYTNGGNATHATGGCNCCN GAYMGNTCNAAYCCNGTNACNACNCCNACNATHCCN---GCNATHTAYCAYAARYTNGTN GAYYTNYTNGTNTAYCARTTYGAYAARMGNATGGAYMGNCCNATGYTNCAYTTYGCNAAR ATHATG------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGNGAYAARACNATHACNGARYTNACNGGNCARGTN GARAAYATHCARGCNGARATGAARCARGTNAARCARMGNAAYAARCARYTNTGYYTNATH YTNGCNCARGGNGARATGAARGAYAARGCNMGNGTNYTNATHCARGTNGAYGARYTNAAY ACNGTNAARGAYGARYTNATGGARCARGTNACNACNYTNACNGCNGARYTNGARMGNGAR AARTCNAARAGYMGNGCNYTNAARGTNGAR------------------------------ ---GAYGARYTNATHGARAARATHTTYAARGTNCARCAYCAYGARYTNGTNTGYGCNGTN TCNTCNAARCCNTAYATHTTYGAYAARGARAARACNGTNGTNGCNTCNYTNGAYAAYAAY TAYTTYTGGTGYAAYTTYTGYTCNTTYTCNTCNTCNAAYAARTCNYTNATH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNATHTCNGGNACNGTNGCNYTNATHCCNTCN AAYYTNAARYTNATHGAYGGNGGNATHACNATHCARAGYAARGTNGCNYTNATHCAYGTN GTNGARAARYTNGTNGCNATGAARTCNYTNTGYACNYTNGCNCAYTGYCCNYTNGTNAAY TGYTAYGTNACNAARAARGARCAYATHCCNGTNGCNMGNGGNGCNTTYAAYTCNYTNYTN CARGARACNAAYGAYYTNAAYGGNTCNGTNCAYYTNTCNCCNGCNATHCARTTYTGYGTN GTNCCNMGNYTNCCNAARGGNGCNTCNGTNGARTGGCARGTNTAYGCNTGGATHTTYAGY AAYYTNGAYAAY---------------AGYMGNCAYTTYACNAARACNTAYCCNTTYTAY ACNATHMGNTTYGAYTGYACNTGGTTYCARGARYTNTTYTCNTGYMGNATHGARGTNTGY TCNACNGGNACNGAYGGNGTNGAYGTNAARGARYTNYTNCAYAAYYTNYTNAAYGARTAY TAYTGYYTNATGGARTCNCAYACNGARGTNTGYGARCARAAYYTNGCNAARATHTTYTTY TCNGCNAAYAARTTYTCNTGYMGNGARYTNGAYAGYTGYACNCARGAYGTNYTNGGN--- ---GTNGAYATGAARAARATGCCNACNTTYTCNTTYATHCCNGTNATHTCNYTNGARTCN GAYMGNCAYYTNYTNGTNTGGTGYCAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARAARAARGARATHGCNTAYAARGARATHTAYTCNCAR AAYGCNGTNGARGARYTNGARGARCARGTNYTNGAYYTNTCNGAYGARYTNCARYTNMGN AARATHMGNGARGAYGARCARMGNAARATGTTYGTNMGNGARAARCARAAYATHATHGAR GARATGGARGAYATHATGGAYGCNGARAARGARAARGCNAARATHGARGAYMGNTAYMGN MGNYTNCARGAYACNYTNAARTCNYTNCAYCAYGAYYTNMGNACNACNAARACNGAYAAR GGNAARAARTCNAAYGGNATHYTNMGNTCNCCNTCNCCNAAYGGNACNCCNAARAARMGN AAYCAYGTNMGNATHTCNTCNACNACNCCNACNAARGARTTYGAYGCNGAYGARCCNATH ------GTNAGYTCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG AGYGAYGARGAYMGNGARATHGAYATHGARAGYGAYGCNGAYGAYGARGAYGGNYTNAAY CCNTTYAGYTCNGTNGAYGAYAARMGNGCNCAYCAYAAYGCNYTNGARMGNAARMGNMGN GAYCAYATHAARGAYAGYTTYCAYAGYYTNMGNGAYTGYGTNCCNCARGAYGAYCARAAR TCNAAYGCNAAYGCNTCNAGYAARACNTCNMGNGCNCARATHYTNMGNCARGCNTCNGAY TAYATHATHMGNATGMGNGAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TAYYTNYTNGTNGGNYTNGGNAAYCAY CCNTAYCCNGARACNMGNCAYAGYATHGGNATGAARGCNGTNGAYMGNYTNGCNTTYAAR YTNGGNYTNCARTGGGARAAYTCNCAYGGNAARCAYGGNGGNTTYYTNTGYMGNACNGAY YTN---------AAYGCNGGNGCNGCNAARGTNTTYYTNTTYAARCCNMGNGCNYTNATG AAYGTNAAYGGNGGNAAYGTNTCNAARACNGCNGCNATGYTNGGNGTNAGYGCNGAYAAY ATHTAYYTNATHCAYGAYGARYTNGAYATGGCNGTNGGNAARTGYGGNYTNAARGAYGGN GGNAGYGCNMGNGGNCAYAARGGNGTNCARTCNTGYATHTCNTCNYTNAARTCNMGNGGN YTNTGGCCNAARGARAARGGN---------------------------------ATGCCN MGNYTNMGNATHGGNATHGGNMGNCCNTCNTCNAARTCNCARGTNGTNTCNTAYGTNYTN AGYCCNGTNCCNTGYGARGARYTNAARTCNATHTCNACNGCNATHGAYCARGGNATGGAY YTNGTNYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AGYGAYGARGAYAARGARAAYGCNCCNAGYAARAARAGYAARAGYAARACNTCN AARCCNAGYMGNYTNACNCCNGTNCARGARGGNGGNGGNAARACNTTY---CAYCCNAAR GCNTTYYTNACNYTNGAYGAYYTNCAYACNAAYGARGCNAAYGGNCAYGAYGAYGAYGTN ATGTCNGTNTCNATGATGTCNGTNGCNTCNAGYTCNTCNYTNGCNTCNGARGTNYTNGAR MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR ATHGARYTNACNATHTCNGCNGARGCNGTNAARATHYTNGAYCCNAARAAYAARATGATH YTNCAYCARTAYCCNYTNCAYMGNATHTCNTAYTGYGCNGAYGAYAARTCNGAYAARMGN ATGTTYACNTTYATHGCNAARGCNGCNGAYAAYAAYGAYCAYTTYTGYTAYGTNTTYGAY AGYGARAARTGYGCNGARGARATHACNYTNACNATHGGNCARGCNTTYGARYTNGCNTAY AARAARTTYATHGARTCNTCNACNCARGAYGTNGAYYTNMGNAARCARTTYYTNYTNYTN CARAARAARGTNAAYTCNYTNCARTTYGARAAYGAYGTNYTNAARAARMGNYTNGCNGAR YTNGARAARYTNAARGAYAGYTCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARATHGARGARCCNTGYGARAGYTCNCCNTCNCCNAARCCNTCNCCNCAR AARAAYAARAARMGNTGYTTYATHTGYAGYTGYAARYTNGARYTNGCNCARMGNACNATH GGNMGNTGYMGNTGYGARCAYGTNTTYTGYCCNATHCAYMGNYTNCCNGARYTNCAYGAY TGYGARTTYAAYCAYAARGARGAYGGNMGNMGNGARGCNMGNGARNNNATGGTNAARCCN ACNMGNCAYATGGGNACNTCNTTYMGNMGNGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GGNATH GARGARTGYYTNTTYTGYTCNTTYATHAGYTCNTCNYTNGARGARAAYGTNACNCAYATG ACNTCNGARCAYGGNTTYTTYYTNCCNGAYGCNGARTAYATHTGYGAYYTNGARGGNYTN GCNACNTAYYTNGGNGARAARGTNGGNGCNGGNCAYATGTGYYTNTGGTGYAAYGARAAR GGNAARMGNTTYCAYAAYAGYAARGAYGTNCARMGNCAYATGGTNGAYAARGGNCAYTGY AARATHYTNCAYGTNACNGAYACNATHTAYGARTTYGCNGAYTTYTAYGAYTAYTCNAAR AGYTAYCCN------GAY---GCNGAYGGNGARAAYGCNCCNGAYATGGARTCNGTNGAY ATHAARGARYTNGAYGGNGAYGGNTAYTCNGTNACNYTNCCNTCNGGNTCNGTNATHGGN CAYMGNTCNYTNATGMGNTAYTAYMGNCARAAYYTNGTNCCNCARATGMGNGTNMGNACN AGYAAYGTNYTNCCNAARATGYTNGCNCAYTAYAARTCNYTNGGNTGGACNGGNGCNACN GGNYTNCARGTNGARCARMGNGCNAARGAYYTNCARTAYATGCARMGNYTNMGNAAYMGN CAYTTYATGAARYTNGGNGTNAARGGNAAYAAYYTNMGNCAYCAYTTYMGNGAYTCNAAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNATGMGNGTNAARAAYYTNYTNTCNTCNCAYGAYGCNMGNATH MGNGTNCARTCNYTNGARGTNGTNGCNCARGCNTGYAARGAYYTNGCNGAYCAYGARMGN GARYTNYTNCCNCARATHCAYCARYTNTGGCCNGGNTTYTAYCCNMGNTTYCAYAGYGAR GARAARTAYGTNGTNATHAARGCNYTNCAYACNYTNMGNGTNATGGCNGAYGTNGGNGGN AAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ACNTGYGTNGCNAAYAARGCNACNATHGTN ACNGTNGGNATHGTNAGYMGNCCNGCNAAYYTNGGNAGY---GARATHACNCAYAGYACN CCNMGNGAYATHATGGCNACNGGNAAYGGNTAYTCNGARCARCAYTAYAAYMGNCARAAY GARAAYTAYGARCARATHATGGARGARMGNAARGCNAARGCNMGNGAYYTNGARCARGAR MGNATGGARGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TCNGCNAGYCCNAARGARGARAARGCNAARAARATHCCNAAR MGNGCNCCNACNGCNTAYATGYTNTTYTGYAAYACNCAYMGNCCNTCNATHGTNGCNGAY AAYCCNGGNATHGCNTTYGCNGGNATHAGYMGNAARYTNGGNGARYTNTGGCARACNCAR TCNAAYAARCARAARYTNCARTGGMGNMGNAARGCNCARMGNMGNYTNAARAARTCNAAY YTNATHTCNACNGGNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CCNYTNAGYCCNTCN AAYAARCCNAGYCAYAARGARGGNTCNMGNTAYAGYCCNACNCCNGAYYTNGCNATHGTN ACNCARCCNAARMGNYTNGGNGAYAARAARAGYGAYTTYYTNMGNGCNATHMGNAAYAAR AGYTCNGTNCARAAYGGNGARGTNTGYCARAAYCARAAYCARAAY---GTNGARAARMGN ACNGARYTNAARCARGAYAGYGAYGTNGAYGTNAARAAYGARAAYTCNAGYTAYAAYCAY ATGAAYGGNGARMGNCARGTNGAYACNAAYGARAAY---YTNYTNAGYGTNAARACNGGN GGNYTNAAYGGNGARATGAARGAYGGNGTNAAYGGNGAY---------TAYYTNATHAAR CAYGTNGAYCAYATHACNYTNTCNGGNGARGAYGARGARMGNMGNYTNYTNYTNTCNATG GGNTGGGARGARGARGAYAAYACNGARTAYGTNATHTCNGARGAYGARATHMGNGARTTY CARAAYYTNGTNCARAAYCAYTGYCAYGGNCARAARAAYGGNYTNAARTCNTCNYTNMGN AGYGCNYTNGAYMGNAARTTYGGN------GCNGAYACNGTNYTNAAYGGNATHCCNTCN GARGARGARAARATHGAYAARAARYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYGGNMGNTAYCCNAGYGARTAYAAYCCNAARGTNCAYGGN CCNTAYATGCCNGGNMGNTTYTAYGGNAARCCNGAYACNCCNTTYGGNCARGTNAARYTN GGNGARYTNGGNTCNTGGTTYGGNMGNMGNAAYAARAGYCCNCAYGCNGTNTGGGGNTCN GTNCAYMGNGCNTAYTGGMGNTGGGCNGCNAAYAAYYTNCAYGTNMGNCAYAGYGGNTTY GTNCCNATHGGNCARGCNGCNATGGTNYTNTCNATHACNTTYTTYGTNYTNYTNTAYAAR GARMGNAGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARGARTCNMGNGCNAAYGGNGAY MGNYTNCAYMGNGARAGYGARYTNGTNGTNCAYAAYGTNAAYACNTGGGTNCARGARCAR AARYTNGCNAAYGARAARYTNGGNAAYAARATHMGNGAYCARAGYAARTCNATHATGGCN YTNACNTCNGARAARGARAAYYTNYTNGAYCARGTNACNAARYTNCARAARAAYTAYAGY AARACNMGNACNGARYTNGARGAYAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARTGYTCNATGGARAGYTCNATHCCNMGNGCNGCNGGNTCNMGNGARGGNGARGTN GAYAAYAGYCAYYTNGARACNGCNTCNYTNTCNGGNTAYGAYTCNGAYGTNGCNAARAAY MGNTCNGGNMGNTCNMGNTCNMGNATHAARACNAAYCCNTGGYTNCCNTCNCCNCARCCN TCNYTNGCNATGGGNMGNMGNTTYGARAAYTGYCAYTTYMGNGARTCNCAYGARGAYGTN ATGTTYTTYCCNMGNTCNGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MGNAARGCNAGYGCNGAYGAYGTN YTNGGNGTNGAYCCNGAYGAYYTNGCNTCNMGNYTNAARTCNGGNGAYGAYYTNGARAAR AARTTYGTNGAYGGNGAYGGNGARGAYGAYGAYTCNGARGAYGAYTCNACNYTNACNGAR GARGARMGNGTNCAYAARAARGTNTTYYTNAARAARMGNAARATGCAYTAYAAYGARTTY CARGCNGTNCARYTNGCNAARAARYTNATGGCNCARGAYAARGAYGAYGAYGAYGARGAY GGNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNAGYMGNTAYAARACNGARYTNTGYMGN CCNTTYGARGARAGYGGNTCNTGYAARTAYGGNGAYAARTGYCARTTYGCNCAYGGNTCN CAYGARYTNMGNAAYYTNGCNMGNCAYCCNAARTAYAARACNGARYTNTGYMGNACNTTY CAYACNATHGGNTTYTGYCCNTAYGGNCCNMGNTGYCAYTTYGTNCAYGARGAYGAR--- ------AARATHGARGGNACNCCNAAR--------------------------------- ---YTNGCNGARAGYGARAGYAGYAGYCCNTCNYTNAGYCCNACNGGNAAYGARAAYAAY ---------TTYTCNTAYTGYTCNGARTCNACNTCNCARATGAAYATHGAYAAYGCNCAR ATHAAYAAY------TCNYTNACNGTNCAYATHAAY------------TAYAAYGGNGTN GAYYTNCARTCNYTNGAR---CARMGNTTYAAYTCNGCNYTNAAYYTN---AAYAAYAAY TGYAAYGARTCNTCNMGNAAY------------------GTNTCNAAYTCNTCNTGYAAR ------------GCNGARGARTAYGAYATHTTYAGYTCNATHTCNGTNTTYAAYGCNGAY GARGTNGTNGCNAAYAAYGCNTCNAARCCNTCNACNTCNACNTAYTCNTCNTAYTCNAAY AARCARACNYTNGAYAAYTAYCCN---ACNTAYGTNGAYACNAAYTGYTAYTGGCARCCN AGYGTNTCNTCNCARAAYATGGCN------CCNGTNGAYCCNTTYCAYTAYTCNCCNACN GGNTCNACNGGNTCNTCNAGYTCNTCNGGNTCNGAY---TCNGGNAGYAGYAGYGAYTGY TGYGGNAGYACNGARAGYYTNGCNGGNTCNGGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GGNMGNTCNAGYGTNCARTCNGAY MGNTTYGARAARAGYATHATHAARTTYTGYCAYCAYTTYTCNGARTTYGAYGCNTGGGAR GTNGARAGYTAYGGNTAYAARCAYGCNAAYYTNAARACNAARYTNMGNATHYTNAARAAY YTNYTNGARTGYCARTTYGAYTTYAAYATHAARTTYAARGARAARGTNAAYGARAGYGAR GCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ACNTCNATGAGYGTNGTNMGNGARACNAGYGARMGNTGYAARGTNGTNMGNAAY ATHYTNCAYAAYCAYATGGTNMGNTAYGARGARMGNGAYYTNTAYATGAGYMGNGARATG CARYTNGARYTNAARCAYMGNYTNCAYCARGARGGNATHGAYGAYYTNAARYTNCCNCAR GTNTTYGCNGAYGGNATHCAYATHGGNGGNGCNGGNCCNYTNGARMGNYTNAAYGARGCN GGNGARYTNMGNGCNYTNYTNGARAGYTAYCARAARATHAAYGTNMGNTTYGCNTGYGAR MGNTGYGGNGGNTAYMGNTTYGTNCCNTGYGARTTYTGYCAYGGNAGYAARMGNTCNYTN ATHMGNAAYCAYTTYACNGARGARTTYTGYGCNYTNMGNTGYATGCAYTGYGAYGARAAY GGNYTNMGNMGNTGYGARCARTGYAARGAYCARCARGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARAGYMGNCARATGAGYCARGARYTNGCNACNATHTCNACN YTNACNTCNMGNTCNGTNAARGCNAARGCNGCNATGAARTTYYTNYTNAARTCNYTNAGY GAYGAYGARGARAAYCCNAARCCNACNGARAAYCAYCAYGARGAYAGYAGYYTNTCNCAR CCNAAYACNTCNACNATGACNYTNCARGARYTNGTNCARGCNYTNACNGAYGTNGTNCAY AARAARGARGARGCNYTNGCNCARCARAARYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CAYGTNCARCARAARATHGCNYTNGCNCARGGNCARCARYTNGAYATG GAYGARGARYTNGARGARATHMGNGTNGARATGACNAARGAYMGNGCNYTNGCNYTNAAR GAYCARGARGARMGNYTNGGNGCNYTNATHGCNTCNYTNCARATGGAYAARGCNMGNGAR YTNGCNAARATHGARGARCARCARMGNGCNATHAAYAAYYTNAARTCNAAYYTNATGGAY GAYYTNAAYGCNMGNGGNATHYTNTCNACNCCNGARTGYCARAARATHYTNAAYATHCAY AARGARGARCARGAYACNATHAAYCARAARYTNGAYGGNCARMGNGCNAARCARGARAAR GCNYTNAARCARAARYTNCARGCNMGNATGGARCARMGNGARCARACNATHYTNTTYCAR CARGAYGARGARATGCARACNYTNATHAARAARGTNACNAAYAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNAGYYTNGAYTTYCCNAAYYTNATHAARATHAAYGGNATH TCNGGNGAYTTYAAYYTNTCNGTNGAYATHTAYGGNATGAGYATHTCNMGNGARATGACN AARGAYAARAARAARAARACNCCNAARAARGGNAARGGNTAYGCNATGGCNYTNGARAGY CCNGGNGGNCCNAGYGCNGTNMGNACNACNAGYTTYAGYCAYGTNTCNTCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AGYGAYTCNGGNAGYGAR GAYGTNAGYATGGTNTAYGARGGN---TCNGGNMGNAARYTNAAYGGNCARTAYGAYGAY GAYGTNTGYMGNGAYTAYATGMGNAAYGTNTGYACNMGNGGNAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNATGGGNYTNACNGAYCCNTAYAAYAGYYTNTCN CAYGARGCNCARGTNTTYACNGAYGGNATHACNTCNATGGGNTTYYTNMGNGCNAARGTN GCNMGNGCNGTNGARAARTTYGGNCARGAYGARAARGARGTNATHGAYCAYYTNTTYGCN GTNGAYGTNYTNGTNGARAARAARTTYGCNCCNATHCAYGCNGARGCNGCNYTNCARTCN TGYAARAAYGAYYTNGARAARGCNGARCAYYTNYTNGARYTNCARGTNCARYTNGARCAR YTNGGNTTYAGYAGYGARMGNGTNMGNGAYGCNYTNGTNACNTCNGAYATGGAYCAYGAY AARGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TGYGGNGTNGARGGNGGNTAYCCNCARGTNAGY AAYGTNACNYTNCAYTGY---GGNGTNGARAARAAYGARTCNGTNGGNATHGARTCNTCN YTNAAYYTNGAYYTNGAYMGNGAR---TGGAAYCARGARATGTGYGTNTGYCARGCNGCN CAYATHACNGGNTGYTAYAAYYTNACNTCNACNTTYACNYTNGAYGTNCARTAYGGNCCN GAYAAYGTNACN---GCNGGNCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGGCN GAYYTNTCNYTNGAYGARTTYATHMGNCARAARAAYGTNAARGTNCARATHMGNAAY--- ACNGCNCARCCNMGNGGNCARATHCARMGNAARACNTCNGCN---------GTNAAYACN AARTTYCARACNAARTCNGTNCARMGNACNTTYGAYGCNMGNTCNAARYTNGGNCCNAAR CCNGTNACNGAYGCNMGNAAYAARATHGTNATHAAYAARAARAAYGGNAARGGNGAYGCN MGNAAYAARATHGTNCARAARCARGTNCARAARGGNACNTTYGAYGCNMGNTCNYTNYTN AAYMGNCCNGGNAARAARACNAAYGGNGCNAAYAAYCCNCARGGNCARGGNCCNCARATG AAYCCNCCNGGNGTN------------------CARCARATHACNMGNACNYTNTCNAAY CCNGTNAAYATGGGNCARATHGGNAGYTTYCARGTNACNMGNCCNGTNCCNGGNACNGAR GTNACNYTNTCNGGNGAYTCNYTNCARGTNACNAARAGYGGNYTNGGNGCNGCNCCNCCN GTNYTNCCNATHGGNGAYTCNGTNCCNATHATHCARATHMGNAAYGAYMGNTAYMGNCAR GARATGCCNCCNTCNCARCCNAGYTGGTCNAAYCARTCNTCNCARMGNYTNCCNCARCCN GCNCAYGTNGARCARTAYTCNCAYCAYAAYCCNTCNTAY--------------------- ------------CCNCCNCCNTAYCCNTCNCARCAYMGNTAYAAYGAYTTYGAYAAYTCN GARYTNCAY---AARCCNYTNYTNAGYGTNCAYGARATHCCNAARATGMGNATHTCNAAY ATHMGNGCNGTNGARGCNGCNGGNATGMGNCCNGTNTCNACNMGNCCNGCNCCNYTNCAR ---------------CCNMGNGCNCCNCCNGGNGCNGCNACN---------------YTN TCNGCNAARCARCCNATHGCNATGTCNMGNTCNTCNTCNATHGGNYTNAARMGNMGN--- CARCCNCCNACNCARGARGTNGGNGGNCCNYTNMGNYTNGGNMGNGGNGGNGGNCCNGGN ATHCARATGGGNATHGGNGARAGYTCNCCNCCNAARAARGCNAAR------TCNGGNATH YTNGCNTCNGAYCCNATHGARATHYTNGAYYTNGARGAYACNTCNAARTTYGTNAGYCCN YTNCARGGNTTYMGNGTNGTNGTNACNAAYYTNTTYAAYGGNGTNACNCARGAYGAYATH ATHGARYTNTTYGGNGTNGTNGGNCCNYTNAARAARGCNMGNYTNYTNAARGCNGGNTCN GCNGARGTNGTNTAYTCNATHMGNGARGAYGCNATHAARGCNGTNCARAARTAYCAYGGN MGNGARYTNGAYGGNCARCCNATGTAYGTNAARATGACNACNCCNTCNACNGCNGTNGTN AARACNCCNYTNGGN---YTNGAYCCNGAYATHACNGGNGARGCNYTNMGNYTNTAYAAR AARCCNAGYAGYYTNGGNGCNYTNCCNGARGCNCCNATH--------------------- ------------------------------------------------------------ GAYTTYGTNCCNMGNTTYATHCARTCNATHMGNGARTAYGTNYTNACNCAYGARTGGACN TGGACNYTNAARATHATHCAYGCNYTNACNTAYGARGAYGGNAAYGCNGAYACN---YTN TGGAARGCNGGNTTYATGTCNYTNATHYTNGARAARAARCARMGNYTNATHGAYCARTTY GTNMGNCARYTNTAYATGYTNCCNMGNYTNTCNTGYGTNGARGTNYTNYTNGAYTAYYTN YTNTAYYTNYTNACNCAYGGNGAYYTNAARMGNGCNGARGAYYTNTCNGARGAYATGAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGNAGYTCN GARAGYAARMGNMGNGTNGTNGTNGARGAYGTNGAYGGNGARGGNGTN------------ ------GTNMGNGTNMGNATGGCNTCNAARAARGARGTNCCNTTYGTNGCNGGNCAYCAR ACNGTNMGNCCNGAYGARAAR------TAY------------------------------ ---------CARGCNATGAGYAARGAYATHGARGAYTTYTAYGTNGARAARYTNAAYGAY YTNCARAARMGNAGYGARGARYTNCARCARCAYTCNAAYGARCARTTYGCNAAYGCNGTN AARGARGTNGARCARAARTTYATGAARTAYACNTCNTCNCCNGTNTGYCARGAYYTNCAR ACNAARGTNYTNGARTGYTAYCARACNAAYCCNGAYTCNATHYTNGAYTGYTCNCCNYTN GTNAAYGCNTTYTCNACNTGYGTNGARMGNGCNMGNYTNACNGTNTCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYACNAAYATGGGNTAY GCNTAYAGYCARYTNAARGAYATGGAYAARGCNGGNGARTGYTTYYTNCAYGGNYTNMGN GCNGCNAARGAYTGYGCNGAYCAYAARACNGARTGGCARAAYYTNGARGCNYTNGCNAGY GTNGARTTYAAYAARAARTCNTAYAARAARGCNGARCARTAYTAYCARCARGCNATHTCN GTNYTNGCNCARGCNCCN---TAYGGNGAYCCNTCNGTNCAYGARMGNYTNGTNACNAAR YTNCARCAYGTNATHCARGTNCARGCNCCNMGN---CCNGCNATHGCNCCNAARGARAAY YTNTCNACNYTNGTNMGNCAY---------GCNAGYAGYCARCARGARAAYGTNAARTAY AARGAYYTNAARTCNATHGCNACNMGNATGGARTCNGGNCAYATHAARGTNATHMGNAAR GGNGAYCARGTNAARTAYYTNAARGTNMGNMGNTCNGGNACNYTNMGNMGNTTYCARAAR GTNGCNYTNGGNYTNGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TTYGAYGCNAAYGAYAGYMGNAAYYTNMGNCAYATHGTNATHGAYGGN AGYAAYGTNGCNATGAGYCAYGGNCAYAARGTNTTYTCNTGYAARGGNATHAARATHGTN GTNGAYTGGTTYAARAARMGNGGNCAYGARAGYATHACNGTNTTYGTNCCNCARTGGMGN AARGARGCNTCNMGNCCNGAYGCNCCNATHTCNAAYCARGARATHYTNACNGARYTNGAR CARGARMGNATHGTNGTNTTYACNCCNGCNMGNMGNGTNGGNGGNACNMGNATHGTNTGY TAYGAYGAYMGNTAYGTNYTNCARYTNGCNGCNGARMGNAAYGGNATHGTNGTNTCNAAY GAYGTNTAYMGNGAYYTNGTNMGNGARMGNGAYGAYTTYMGNGARGTNGTNGAYAARMGN YTNYTNATGTAYTCNTTYGTNAGYGAYACNTTYATGCCNCCNGARGAYCCNYTNGGNMGN CARGGNCCNTCNYTNGAYAAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GAYGAYGAY GAYCCNGTNTCNAAYATGACNMGNGAYGTNTGYGCNGAYATGYTNGARTCNATHMGNAAR YTNAARGARYTNGARTCNGAYAAYCCNAAYATGAARMGNATHYTNGARATGCARGCNCAR YTNACNGAYYTNCARAARTCNYTNATHAARCCN--------------------------- ---------------------------------------------------GGNACNACN AGYAGYAAYAGYAARYTNCCNGGNGARAARMGNCARAARGAYYTNGCNAAYYTNGARGAR ATGTTYGARGARGCNGAYMGNGCNGARMGNCARMGNGARGARGARATHAARCARCARMGN GARGCNGARYTNAARAAYAARMGNGARYTNGARYTNAARMGNAARTTYCARTGGGCNMGN AARGTNATHYTNGAYTAYAARCAR------GARAAYGTNAARGGNGARATGAGY------ ---GARGARGCNGGNAARATGYTNAARCARMGNGARCARMGNATHAARGARGARGARGAR AARYTNCARGARAARGGNGARGARGARMGNAARGARGCNGARMGNAARMGNYTNATHCAR AARATHGARGARGCNMGN---------------YTNAARGAYTCNCARAARGCNGAYAAR YTNTCNACNTCNCARYTNYTNTGGAAYACNTCNGAYCAYGAYGGNTCNCCNAGYMGNCAY ------GGNTCNGARGCNACNAGYGAYAAYYTNTAYATH--------------------- ------------------------------------------CCNGARGCNGARGGNGAY GARGTNGARGAYTTYACNGTNGTNYTNGARAAYGAYTAYCARGAYYTNTGGGCNCARAAR YTNYTNCAYACNYTNCCNGTNAAYTAYMGNGTNMGNYTNTCNAGYATGGTNAAYMGNTAY TGYCCNATHCARAGYTGYCCNGCNAARACNTGYTTYMGNGAYGARACNGCNTAYCARGAR CAYTGGTCNATHTTYCAYGARCCNCAYACNACNATGMGNTTYTGYCARAARTGYTCNGCN TAYTTYATGAAYTGYGARGARYTNGARAARCAYATGATGAAYCAYCAYCAYYTNACNTCN ---YTNGARGCNAAYAAYYTNTCNYTNMGNTCNMGNATHAARGTNGTNCCNAAYCCNAGY TTYMGNGAYCCNYTNCCNTTY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNCAYTCNAGYTCNTCN TCNMGNTCNACNAGYMGNTCNAARTCNMGNTCNMGNACNCARTCN--------------- ------------------------------------------------------------ ---CCNMGNAARGAYTCNAARMGNTCNMGNTCNAARAGYGTNGAYAARATHCCNGTNAAR MGNTAYMGNMGNGARAGYYTNTCNAGY---TCNGGNYTNAGYGAYYTNGARTCNGAYGAY GAYCAR---TCNTCNCAYTCNTCNACNTCNMGNTCNAARCCNGGNGAYCARTCNAARACN AGYYTNGTNACNGGNGGNAARYTNAAYAGYAARAGYAAYCCNCARGCNGTNAARGARTCN CCNCARGARMGNYTNAARMGNMGNATGCARGCNCARYTNAAYAARCARTTYMGNGCNGAY AARAARGCNGARATHACNAARACNTCNAARCARGARCARGARMGNYTNGAYMGNGARGAR GARATHAARACNATGGCNATHGARATGMGNMGNMGNGARMGNGARMGNMGNCAYMGNGAR AARGARGAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AGYGTNGAYTAYAGYACNYTNMGNGARGCNGGNATGGCNTGYCARCARATGMGN ACNTGYYTNAAYGARATHTGYACNATHATHTCNYTNGCNTGGATHACNGARYTNCCNCCN GTNAAYGAYCARGGNMGNTTYTAYGAYCCNGARTCNACNCARGARAAYGARAARYTNACN TTYGARYTNAAYGARYTNCARTCNAARTAYGCNGTNYTNGAYGTNACNGTNAARGAYCAR CARGARAARYTNAAYGTNTCNAARCARMGNCARAARGAYYTNGARCAYTCNGTNTGYMGN CARGTNATGAAYAARGGNAARCARACNMGNAGYYTNTCNGCNTCNTTYGAYGAYGARMGN GAYYTNACNGARTCN---------------GAYGAYMGNGTNACNATGATGGAY------ ------MGNGAYATGGARAGYGARAARAAYACNACNGAYGAYTGYAGYAARATGYTNAAY CCNGARYTNMGNGGNCARTAYGARCARATHAARAARTCNTAYGCNGAYYTNYTNTAYAAR TGGGGNYTNYTNAAYCARMGNACNCARGTNYTNAARCAYACNYTNTCNGTN---CARGGN GAYAARAARATHGARTTYCCNATHCCNTGYTCNAGYTGYTAYGAYGCNGCNYTNAAYGTN CARTGYAAYAARTGYCAYCAYCCNTCNYTNAAYTGYTCNATHTGYCAYGTNGGNGTNMGN GGNCCNGCNAAYGTNTGYYTNGTNTGYGGNCAYGGNGGNCAYTCNAGYCAYATGATGAAR TGGTTYCAYACNAAYAARYTNTGYCCNTCNGGNTGYGGNTGYAAYTGYYTNCARGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNAARGARCARYTNAGYAAR TGYMGNGARGARAAYAARTGYAARTCNACNATGYTNTGYGARTGYGARGARGCNTTYAAR MGNTGYCARYTNYTNAGYCARGAYAARGAYGAYGARATHCARYTNYTNCARTGYCARATH GARACNYTNAAYAGYAARYTNTCNGARMGNATHGCNMGNGTNGAYGARYTNGARMGNGGN ATHGARAAYYTNCAYAARGAYGTNGARMGNMGNATGATGMGNGTNGAYGARCARYTNAAR AARTAYGARTCNGARYTNGTNGAYMGNYTNCARGARATHGCNGARYTNAARGARGTNGTN AAYACNTGYCARYTNAAYYTNGCNGARAAYATGGAYGARATHCAYCARCARGARCARAAR ATHTGYYTNYTNACNGGNGARYTNCARTCNYTNAARYTNAARYTNAARGARGCNGARGAY GCNMGNGAYCAYYTNAGYAGYCARYTNYTNGAYAARAARTCNGARGTNGCNGARYTNACN CARCARYTNMGNATHAAYMGNGARCARATGCARAARCARCAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CAYATHGGNGGNCARGARTTYCAYATHAARCARGAYTGGTAYGCNGGNGGNGTN GCNGCNGTNGTNTGGGAYGCNGCNATHGTNYTNGGNGARTTYYTNGCNTCNAAYAAYGTN YTNGTNAARGAYAARMGNGTNYTNGARYTNGGNGCNGGNACNGGNYTNGCNGGNATGGTN GCNGCNACNYTNGGNGGNGAYGTNATHGTNACNGARMGNGARGARGCNYTNACNTAYYTN AARACNGCNATHGTNAARAAYMGNYTNGGNMGNGAYTGGAARATHAARGCNGCNGTNYTN GAYTGG------ACNCARGAYATGGAYGTNGAYACNTGGGGNGARGTNGAYYTNGTNATH GGNGCNGAYATHATHTAYATHGARGAYACNTTYTCNCAYYTNYTNAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTNGTNACNCAYTTYGGNGGN TGYCAYTGYGGNGCNGTNMGNTTYTCNGTNCARGCNCCNGCNCAYYTNGAYGTNGTNGAR TGYAAYTGYAGYATHTGYACNAARAARCARAAYYTNCAYTTYATHGTNCCNAARTCNMGN TTYAARATGATHCARGGNGARAAYACNYTNACNACNTAYACNTTYAAYACNCAYAARGCN AARCAYATGTTYTGYAARGTNTGYGGNGTNCARAGYTTYTAYAGYCCNMGNTCNAAYCCN GAYGGNTAYGGNATHATGCCNCAYTGYATHGAYCCNGGNACNATHGARTCNACNAARATH GTNACNTTYGAYGGNAGYCARTGGGARAARTCNTTYGARAARTCNAAYATHACNGARTAY TCNAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARAARTTYAARAARGARGGNATHTCNGAYGCNGCNTCNAGYGCNGARTAYATH ACNGCNCAYGTNYTNGGNAARAARACNYTNCAYAAYGTNAAYAARAAYGAYYTNGTNYTN GARAARGAYGAYGTNGCNGCNATHCAYCARYTNTGYAARYTNMGNYTNAARMGNATGCCN GTNCARTAYATHYTNGGNGARTGGGAYTTYCAYGAYATGACNYTNAARATGGTNCCNCCN GTNTTYATHCCNMGNCCNGARACNGARGARYTNGTNGARCAYTGYAARCAYATHATG--- ---GARTCNTAYTGGTCNMGNTGYGARCAYCARCCNTTYGTNYTNGARGTNGGNTGYGGN AGYGGNGCNATHACNYTNGCNYTNYTNAARCAYTTYAARCARYTNAARTCNGTNTGYGTN GARATHTCNCCNGTNGCNTGYGCNYTNACNCARGCNAAYGCNAARAARGTNGGNGTNGAR GAYMGNATHACNATHTTYAAYGARGAYTTYACNAAYMGNGARGTNYTNTCNGARYTNCAR TCNYTNGGNCCNTTYTCNYTNTTYGTNAGYAAYCCNCCNTAYGTNACNACNGARGARATG AARAGYYTNTCNTCNGARATHGTNMGNTTYGARGAYCCNGTNGCNYTNGAYGGNGGNYTN GAYGGNYTNGAYYTNGTNMGNTAYATHYTNCARCAYGCNGCNCARYTNYTNATHCCNCAR GGNCAYYTNYTNYTNGARGTNGGNGCNGAYCAYCCNGAYGTNATHAARGAYTAYGTNACN AARACNTCNGAYACN---AGYYTNCARTTYATGGARACNATHAARGAYATGCAYAAYMGN ACNMGNTTYTGYCAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARMGNYTNATGGARYTNAARGCNGAYAARGGNGAYYTN GARGGNYTNGGNYTNCCNGAYCAYYTNYTNTCNTCNYTNCARAAYYTNCARGARGCNGTN CARTCNYTNCARGARGGNCARTCNAARGAYGGNGCNGCNATHMGNMGNYTNCARGARYTN YTNAAYAARATHCARACNGAYYTNGARCARYTNMGNAGYGCNYTNGARAAYGCNYTNGGN GARAAYGAYGAYMGNAARAARGARATHAARGAYYTNAAYGARMGNTGYGGNAAYYTNGAY AARACNAARGCNGAYAARCARTAYGTNGAYATGGARGTNGARGTNAARGCNGAYMGNAAY CARYTNGARGGNAARGTNAAYCAYAGYYTNTTYGAYACNACNACNAAYGARYTNAAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGTTYAARAAR ACNAARTCNAARGTNGTNCARAAYGGNAGYMGNGARTCNGTNGAYAGYCARGTNAGYAGY TCNAGYGCNAGYAAYGARAAYYTNTCNCCNAGYACNAARGARATHAARGARACNGTNGAY AARATHYTNCAYCARMGNGTNCAYTTYCARGTNTAYTTYYTNGGNYTNGTNCCNGARATH AAYYTNACNAAYTCNAARAARMGNGAYGCNGARGCNCARYTNATHGAYGTNGTNGARGAR AAYCARATHGARGGNMGNYTNCARGTNACNGCNACNGAYGARAAYAARGTNGTNATGAAY GTNTCNMGNCAYGGNATHAARGTNYTNGAYATHGCNGGNAARGARGTNYTNCARMGNCAY CCNYTNCAYACNATHGCNCARYTNACNGARTAYAAYGAYGGNTTYGGNMGNCARAAYATH GCNGTNAARATHGGNCARGTNGGNAARAAYGTNTAYCARTGYTAYGTNTTYCARTGYCAY TCNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNCCNTGYMGNTCNMGNAARMGNCAYMGN MGNAAYAGYAGYCAYAARGARGTNACNGARGARAGYGCNATHAARCCNGARGAYCARGTN ACNGAYGARYTNAAYATHACNTTYAARACNCAYAARAAR------YTNCARGARTCNACN TCNGGN------YTNGCNGARGTNACNAARACNGGNGTNAAYAARTCNACNGCNGCNAGY AARGAYAARGARACNCARTCNAAYACNACNCCNAAYGGNGAYATHGCNGGNAGYMGNAAR MGNGGNGCNAGYATHTCNAGYACNGAYGGNACNACNCCNGCNAARGCNAGYAARGTNGAR AARGTNGARGCNGCNGARGAYACNTGGAGYAARATGGARGGNYTNTAYGARGCNAARGAR GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TAYGARAARTCNGARATHGTNGARAAYYTNGGNYTNGAYCARMGN GARATGGTNGCNGCNGCNYTNYTNACNGGNTGYGAYTTYTGYTCNGGNGTNGAYGGNATH GGNATHAARAARTTYYTNCAYYTNGTNAARGARYTNAARMGNAAYCAYGTNGAYGAYATH YTNGAYTGGATGMGNTCNYTNMGNACNAGYGARCARYTNCARTCNYTNAARGARACNATG GTNATGAARAAYAGYATGAARAARGARGCNCAYTGYTCNACNTGYTCNCAYYTNGGNTCN GTNAGYAARCAYAAYAARAAYGGNTGYGTNATGTGYTCNACNCAYGARGGNTGYAARAAR CARAAYAGYYTNTCNTCNGAYAAY------------ATHGCNTGYTCNTGYMGNTTYCAY ACNYTNGARGAYGARGTNGAYCCNTTYYTNACNCARYTNAARGTNTCNGARGCNGCNYTN AARCARCCNAAYTTYCCNAGYGAYGARGTNATHGCNGARTTYYTNAGYGARGAYAARAGY ATHTCNAARGAYACNGAYATGGAYGCNAARAARCCNAARTCNCARGARGTNATHMGNYTN YTNACNGARTCNYTNGGNATHAGYCARAARGAYACNAARCARTTYTTYCCNGCNYTNGTN AARATGTGYYTNTAYGGNCARYTNCCNGTNGTNGARATHTCNCCNGTNAARGTNGTNMGN AARTGYMGNAARGAYAARGARCARTGYTAYYTNGTNGARTTYAARAARTTYGARTTYGAY AGYAGYGGNGARAARGAYGTNTAYGARATHCAYGTNGCNCARAGYATHTTYGAYGARAAR TTYCCNCARTGG------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGGAY ACNACNGARATHTCNMGNYTNMGNGARGARCARYTNAARGCNGTNACNGARACNACNGAR AARATHACNCARTTYGARAARTAYAARTCNGAYTAYCARGCNYTNCARAARAARYTNAAR ACNYTNCCNGAYAARYTNTCNCAYGAYGTNATGATHCCNTTYGGNAARYTNGCNTTYATG CCNGGNCARATHGTNCAYACNAAYGARGTNYTNGTNYTNYTNGGNGAYAAYTGGTTYGCN GARMGNTCNGCNAARCARGCNCAYGARATHGCNAGYMGNMGNATHAARGARYTNAAYAAR MGNATHAARGAYYTNAARGARCARCARAGYYTNYTNGARCCNMGNYTNCARATHACNTCN GARYTNCARGCNCARGCNGARGGNACNGGNGARTAYCAYGARATHGTNGARGARTAYGAY GARGARAARGARMGNYTNTGGGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CCNGTNAARMGNAARGCNTGGATHTCNTTYYTNATHYTNGTNGTNAARCARAGY TAYGTNYTNTCNYTNATHGGNATGATGGCNTGGAGYATHACNTAYCAYTCNTGGYTNACN TTYGCNYTNYTNYTNGCNGCNTGYGTNYTNTGGATGATGCCNAAYTCNMGNAARTGGTGY YTNMGNGCNTCNCCNTGYATHYTNGTNTAYGCNGARYTNYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNGTNGAYYTNTCNTCNATHAGYCARGAYACNCCNTTYTGGGAYMGN CAYTTYAARGGNAARACNGARGTNACNTGGATHGARTTYMGNGAYAARTTYYTNAAYGAY TAYGGNTCNAARATHATHGARGGNTTYTCNAAYAAYCARGARGARMGNAARAARTTYTTY ATHAAYYTNATGTAYAARGAYGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TCNGCNTTYAAYGTNGAYYTNMGNACNGCNGTNATHCAY GARGGNAARAAYGGNAGYATGTTYGGNTAYGCNGTNGCNCARCAYATHGAYCARTCNACN AAYTGGGTNYTNATHGGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GTNACNAARTCNGAYAARAARATGGAYACNTGYGTNCCNAAYCCNAGY YTNATHAAYACNCCNTGGGCNACNAGYCCNCAYTCNTTYTCNATHTAYGAYCARGARMGN CCNAGYAAYGTNTTYTGYMGNGGNTCNAARGTNAAYACNYTN---------------GAY ATHGGNGGNYTNAAYGARGARGGNGGNYTNGAYGAYAAYTTYGARGAYAGYTCNYTNAAR AGYATHYTNACNCCNGARYTNATHAAYTCNATGTCNTCNTCNTCNGGNYTNACNACNCCN TCNTTYCARTGGGGNATHAAR------------AAYAAYCARGARGARACNCCNAAYCCN GCNATHGCNATGGARTCNTTYATGCARYTNGGNATGGAYCCNGAYYTNYTNATHNNNCAR TCNTTYTTYAAYATHGAYTCNAAYGAYAGYAARTTYTCNTTYCCNACNTTYGAYYTNGAY TCNATGACNAGYAAYCCNCCNTCN------------------------TCNTGYCAYACN CCNGTNCCNTCNGARTCNMGNACNGAYTTYYTNGARACNTCNTTYGAYMGNMGN------ AAYTCNATGTCNCARAGYAARGARACNCCNYTNAARGAYAAYATHGGNACNGAYTTYYTN CARAARAARTTYCCNATGAARACNAAYTTYCCNCCNMGNACNTCNCARCCNCCNGTNGGN GTNGTNGCNCCNGTNAARATHCCNGARGAY------------------------------ ---------------------------------------------------------AAY YTNATHTTYAAYGCNCAYATGGARATGGGNATGAARGAYTCNAARYTNAAYATHGCNATG GAYGTNGCNGAYYTNGCNCCNCARACNGTN---CCNTCNTTYGGNGAYGAYTCNACNCAY YTN---------GTNAARYTNGARCCNGCNTCNCCNGAR---TTYAGYAAYAARMGNGGN TCNAARMGNTCNGTNGAYGAYACNTGGGARGAYGTNAAYCAYYTNATHTCNAGYGAYYTN GCNACNACNACNAARAARMGNMGNMGNTGYGAYTCNGGNAGYTCNGGNCAYACNTCNGAR GAY---GTNGAYGAYGAYGARAAYGAYTTYGTNTAYAAYATGGAYGAYGAYAGYGAYGAY ---------GAYYTNGAYGCNGAYYTNGCNTAYATGAARCCNGGNTGYTGYGARTCNYTN ATHGARGGNGGNAARAARCARAARCARTAYTTYTGGCARTAYAAYGTNCARGCNAARGGN CCNAARGGNACNMGNYTNAARYTNGCNGTNGARGCNCCNACNGAYCCNCAYGTNYTNAAY GGNTTYGARGAYCCNGTNTTYGAYGARGGNAAYACNCARGTNGCNGGNATHMGNCAYGGN GGNAARGCNMGNAARGGNGAYGGNAAYGARGTNACNCCNAAYCCNCAYAARYTNTTYMGN ATHGGNCAYCARYTNYTNMGNYTNAGYAARGARATHAAYGCNTGYCARYTNGGNTCNGAY GTNCCNYTNGCNAARMGNAAYGARTCNMGNAARGARAARAAYAARYTNGCNTCNMGNGCN TGYMGNYTNAARAARAARGCNCARCAYGARGCNAAYAARATHAARYTNCAYGGNYTNGAR ACNGARCAYAGYCARATHAAYAAYGTNYTNMGNYTNATHYTNCCNAARYTNMGNGARMGN GCNAARGCNYTNCAR------------AAYAAYCAYGTNACNGARAARCCNGAYCCNGAR AAYAGYYTNACNAAYATGYTNACNGGNATHATHTCNTCNAAYYTNAARACNATGGTNGCN ACNCAYACNACNGAYTAYGTNAAYAAYGTNATHYTNACNGTNGARMGNGGNGAYYTNGGN GGNGGNYTNAAY---YTNAARACNMGNAARACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MGNTTYAARCARTTY ACNGGNYTNGTNGAYAAYTAYGTNTAYGAYYTNGGNGARAARGARACNACNCCNACNGAY YTNCARGGNTTYTGGGAYATGATHTAYTTYCARGTNGARGAYGTNGAYTCNCARTTYAAR CARYTNGARGTNYTNAARGARTCNAAYTGGCARYTNAARACNGAYTCNCCN--------- ---------AARGTNAARGTNGGNYTNAARAARAARGCNGTNCCNAARGGNGTNAARTCN AARGGNAARTCNAAYTTYGCNGCNTTYMGNGCNGARATGYTNAARAARAARGCN------ ------------------GARGAYYTNAARAARATGAARGTNCCNGARYTNAARCARGCN YTNAARGARAARAGYYTNTCNACNTCNGGNACNAARCCNGARYTNATHAARMGNYTNGTN GARGCNATGGGNTCNTCNGTN---AGYGGNAGYGAYCCNGTNYTNGAYGAR--------- ------GAYGARATHYTNAARGAYGAY--------------------------------- ------CCNGCNCCNTCNGAYACNCCNGTNCCNTCNAARCCNTCNACNCARTCNCCNACN GTNACNTCNGAYAGYAARCCNAAYGGNGTN---------ACNAAYGAYCCNYTNCCN--- ------ACNGCNGCNGAYACNACNGTNATHGCNAARCCNACNGARGTNAGYAARYTNTCN GARGCNGARMGNYTNAARYTNMGNGCNGAYAARTTYGGNYTNTCNTCNGARCARTCNAAR AARGAYTCNMGNGCNCARMGNTTYGGNATHCCNACNAAYGARACNAARTCNGGNAGYATH AGYACNTCNGCNGARCCNGTNGAYGTNGARAARYTNAARAARMGNGCNGARMGNTTYGGN GTN------------TCNACNAGYTCNGTNACNCARGAYGARYTNAARMGNAARMGNGCN GTNATHTTY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GARATHAARYTNYTNCARGAYCARYTN GTNCARGCNGTNATHAARGAYAARAAYAGYYTNCCNCCNYTNATGCARTCNATHGTNGGN GARAARGTNACNGARACNATHYTNCCNGAYCARATGGARAGYYTNTGGGAYAARYTNGAY TCNATHATGGARGCNMGNMGNGAYYTNAARGARTTYGGNTAYYTNGTNGAYCCNGGNGGN GCNATGAGYCCNGCNACNATHAARCCNYTNYTNMGNCARGTNATHGAYAARATHGTNGAY CCNTCNAARCCNGARYTNCCNGAYATHGARTGYAARTCNGGNGGNYTNAARGAYYTNYTN AARTCNGGNTTYGGNTTYTTYAARAGYTCNGCNAARCCNMGNCCNGGNGAYGCNCCNYTN YTNATHGTNATHGTNATHGGNGGNGTNACNGCNTCNGARGTNAARCARGTNAARGAYGTN GTNAGYAGYGCNAARCCNGGNTTYGARATHGTNGTNGGNGGNACNMGNATHATHAGYATH GAYTCNACNYTNACNTCNYTNYTNGTNAARGAYAAYATHAAYATH--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TAYGARTCNGAYATHYTNACNAARTAYAARGARAAYATHTTYYTNGTNACNGAR TGGYTNCAYAGYGAYATHAGYTCNACNAARATHMGNMGNGCNTGYMGNMGNGGNGARAGY ATHAARTAYGTNGTNCARGAYTCNGTNATHGAYTAYATHMGNGARCARMGNYTNTAYGGN TTYCCNGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATHGARGAYGTNATHTGYYTNTTYYTNGTNACNTTYCARMGNCCNTGYCCNCAY YTNGTNATGGGNCAYCARCCNTGGAARTGGYTNTTYGCNTCNATGGARTGYCARAARYTN GTNAARGARGGNCAYTTYGCNTCNGCNYTNCARAARYTNCAYYTNTCNGTNAARGAYTGY CARGARCCNGTNTAYAARTGYMGNYTNYTNTGYYTNTTYGCNGAYTGYTAYTTYCAYATG GGNTGYCCNCARYTNGCNATHCARACNTAYMGNGAYGCNYTNCAYGTNGAYAAYAARTGY TTYTCNATHYTNTAYCAYYTNTCNYTNATHTAYCARAGYYTNAAYYTNCCNGAYYTNGAR YTNGARTCNYTNAAYYTNTGYGTNATGGCNYTNGCNGAYGARCARAAYMGNAARAARGAY MGNATHCCNGTNATG---GAYATGGAYGARYTNATHTGGTCNGTNCAYCCNGCNACNCCN CCNGTNACNTTYYTNAARTCNAARGTNGCNTTYGCNAARMGNTGYYTNCARYTNCARMGN TTYCARGARGCNGCNGARCARTAYTCNAGYYTNATHCARATGYTNCARCARGAYGAY--- ------GAYGAYGTNYTNGARTTYGARATHCAYGARATHAAYATHGCNGARATHYTNGTN GARGCNGCNGARGTNYTNYTNATHACNMGNCARTTYCARGAYTGYYTNAARATHTGYAAY CARACNCARCCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNCAYCCNACNGAYTGYCAYAARTTYYTNGTNTGYGAYCAY GGNCARCARGTNACNATGGAYTGYCCNGTNCARYTNGTNTTYAAYGARACNGCNCARGTN TGYGAYTAYAARTCNAAYGTNCCNMGNTGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNYTNAAYYTNGAYMGN YTNGTNTGYTAYYTNTGYGGNATHGAYAAYCCNMGNYTNYTNTAYTCNGARAGYGARAAR TTYYTNGGNCARTTYCARGGNGAYYTNTCNCCNAAYCARTAYMGNCCNTTYAAYYTNTAY CCNATGAARTTYGTNCAYGAYYTNAGYTTYTGGGARMGNGAYGTNGAYTCNGARCCNTTY GAYGTNTTYAGYYTNTAYGARACNGTNMGNAAYATHGCNGGNGAYGTNGTNGAYAGYGTN TGYYTNATHGAYGTNTAYGARGARCCNGAYACNMGNMGNMGNAGYMGNTGYTAYMGNYTN TAYTTYCARTCNGTNGAYAARTGYYTNTCNTAYGTNATGTCNTGGAARYTNCARAGYCAR ATHMGNATGGARGTNTCNMGNAGYYTNGGNGTNCARYTNMGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GCNCCNAARGARATH ACNGTNYTNATGAGYGCNAAYMGNGGNGARGTNACNTCNGTNCARGGNTCNCCNGAYYTN MGNGTNACNAAYTTYTCNYTNGAYATHCCNATHCCNAGYTAYYTNYTNGCNATHGTNGCN GGNGAYYTNGARTCNMGNGAYATHGGNCCNMGNTCNAARGTNTGGTCNGARAARGARTAY GTNGAYATGGCNGCNTAYGARTTYGCNGARACNGARTCNATGYTNCARGTNGCNGARGAR YTNATGGGNCCNTAYYTNTGGGGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARAARGAYAARAGYMGNYTNCARATGCARYTNGARMGNACNACNMGNYTNYTNACNGAR YTNGGNCARCARGAYMGNGTNYTNGTNGAYTCNTTYGTNACNAGYTCNCCNCCNCCNTCN AARMGNAARAARMGNGAYACNGARTCNTCNGAYGARGGNGTNGGNTCNYTNTCNGAYGCN TCNGAYGAYATHAGYACNGAYYTNTGYCARAARCAYGARGCNYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARATHCCNTCN GTNYTNGARCARTAYYTNAAYTGYGTNGCNAARAAYGGNGARACNYTNTTYCCNTGGTCN CARYTNAARCCNYTNATHYTNMGNAARATGGARYTNGTNATHATGGARYTNMGNMGNAGY YTNGCNTCNGARAAYATHCCNAAYMGNCCNAAYGTNGARAAYGTNMGNTTYGAYGTNATG CAYGCNMGNATHATHGAYTCNYTNCAYAARTTYAAYGGNGCNCCNTTYACNATHCARMGN YTNTGYGARYTNYTNATHGAYCCNAARMGNCAYTAYAARMGNACNGAYAARTTYATGMGN GGNYTNGARAARAAYGTNYTNGTNGTNAGYACNGTNGAYCCNTTYGGNMGNAARGTNGTN TGYGARTCNGGNAAYAARCCNATGYTNAAYGGNATHATG---GAYATHAAYGGNTCN--- TAYCCNCCNMGNGAYTCNGCNYTNAGYGTNCCNYTNCCNCCNGTNCCNGGNTGGGTNACN ACNTCNTCNGCNGCNCCNTCNMGNACNGCNGCNACNGTNYTNCCNCCNGAYTCNAARGTN GGNACNGGNACNCCNGTNGARAGYYTNAARGAYGCNGAYGTNGTNTCNAAYGGNGTNCCN GGNGGNATGTCN------AGYTCNGTNTTYACNGAYCAR---GAYGAYCCNYTNGCNGTN CARTCNGARGARGTNGTNGARGARACNGTNGTNACNATGGAYACNGGNGARGTNAGYTCN GTNGTNACNGAYGGNGGNGARTCNATGGCNGARGGNGARGCNATGGARGGNGARATG--- GCNGAYGAYMGNGAYGCNTCNTCNTTYTCNTCNTCNTCNTCNTCNTCNTCNGARGARYTN TCNACNTCNTCNGAYTCNATHTCNCCNTTYGGNGTNGTNATHAAYAAYAAYTTYAAYGAY GARGCNTCNYTNGAYGARAAYMGNCCNTGGGCNGCNTTYGCNGAYGTNAARCAYCAYGAR GAYGTNACN------TCNCAYCCNTCNGGNAGYCARCCNGTNAARAAYATHCCNGAYGAR AAYCARACN---------------------CCNGCNGCNTCNTCNTCNTCNCCNTCNACN AGYACNGARGCNTCNTCNTCNYTNTCNTCNTCNTCNYTNCCNTCNTCNGARACNCARTCN ---------------------------------------TCNYTNYTNTCNACNACNACN TCNTCNAARGCNGARGAYAARATHGARAGYCARGAYYTNAAYCARTCNACNCCNTCNTGG GTNCCNACNGAYGAYTCNGCNAAYGARAGYYTNGGNTTYGARCCNGTNAARTCNGCNTCN GAYCAYGTN---------------------YTNTCNTCNCCNGARGAYACNCCNAAYTCN GTNTCNGARCARGCNTCNTCNACNACNACNACNGARACNACNATHACNAAYAAYCCNACN CCNGAYCCNACNAAYACNGCNTCNTCNYTNTCNTCNTCNTCNCARAGYGTNCCNACNTAY GCNCARGTN--------------------------------------------------- ---------------------------GTNGCNTCNTCNACNGAYATHCAYYTNACNCCN TAYGAYTCNTCN---------------------GARACNGTNCCNTGYGAYAGYGTNGCN GGNYTNGARMGNYTNGTNGGNTCNATGGARCARTCNYTNTCNTCNTCNCCNTCNTCNTCN GCNTCNATHGCNMGNATHTCNTCNTCNTCNTCNTCNCAYCCNGAYATHACNCCNAGY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MGN MGNTGYMGNTTYGTNATHGGNTCNMGNCARTGYGTNAAYMGNTAYYTNCARCARTTYAAR GAYYTNTTYACNGARGARGGNAARYTNCARATGAARATHACNATHMGNAARGCNAAYGAR CCNTCNCCNACNATHACNTAYACNCARGGNYTNGCNAAYGCNCCNGTNGCNCCNCCNGTN CCNCCNAGYACNATHGCNATHAAYACNGCNCARGCNGCNYTNATGAARCARGTNGCNATH AAYCARCARGCNGTNAARGCNGARATGGGNCCNGCNGTNGCNGGNYTNGCNACNAARMGN AAYTTYCCNATH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYYTNGAYYTNTCNAGYCCNAAYTCNTCNTCNGGNAARAARAGYTCNCAYAAR GAYGGNGGNAGYTCNAGYAARCARGGNCCNAGYCCNAARTCNAGYMGNGARAAYACNCCN GARAARMGNTCNTCNGARMGNGARAARTCNTCNGAYMGNGARAARACNCCNGARGGNAGY GAYAARGAYAARMGNYTNTCNGARTCNCCNGAYGAYACNAARCCNTCNACNTCNGCNCCN TCNACN------------TCNCCNTCNGCNTCNCCNTCNCCNGARAARAARMGNAARAGY GCNTTYACNGARGARGARYTNAARCARGCNATHAARMGNCAYAARAARCARGAYGARGAR MGNATGAARATGCARGTNYTNGTNTCNAAYTTYTCNGARGARCARYTNAAYMGNTAYGAR ATGTTYMGNMGNGCNACNTTYCCNMGNGCNGCNATHAARMGNYTNATGCARAAYATHACN GCNACNACNGTNTCNCARAAYGTNGTNATHGCNATGTCNGGNATHTCNAARGTNTTYGTN GGNGARGTNYTNGARACNGCNYTNGAYGTNAGYGARAARTGGGGNGAYTCNGGNCCNYTN CARCCNAARCAYYTNMGNGARGCNGTNMGNGTNYTNAAYTCNAARGGNATGATGCCNTCN ACNAARAGYAARAARTGYYTNTTYACNACNATGTCNGCNAAYACNAARATHGAYATHCCN AGYGARAAYGCNYTNGGNGCNGTNCCNGCNYTNATHAGYGGNGAYCCNAGYAARYTNACN MGNGGNYTNATHGTNYTNCARGARTGGTGGGGNATGAAYCARCARATHCARGAYTGYGGN AARGAYYTNTGYAGYMGNGGNAAR---YTNGTNACNGTNGTNCCNGAYYTNTAYMGNGGN AARGTNGCNAARGAYCAYGARGARGCNGGNCAYCAYATGGGNAAYYTNGAYTGGAARGGN GCNGTNGCNGAYATHCARGCNTGYGCNAARTAYYTNAARAGYAARGGNGTNAARAARGTN GCNGTNACNGGNTTYTGYATGGGNGGNGCNYTNTCNATGGCNGCNGCNGCNYTNGTNCCN GARGTNGAYGCNGCNGTNCCNTTYTAYGGNATHCCNTCNCCNTCNYTNTGYGAYGTNACN ACNATHAARGTNCCNYTNCARTGYCAYTTYGCNYTNCAYGAYCARACNGCNGGNTTYGCN TCNCCNGCNGARTGGAARCCNYTNMGNACNAARYTNGARGGNAARYTNAARCARYTNGAR TTYTAYGARTAYGAYGCNGGNCAYGCNTTYACNAGYAARTCNGGNGAYAAYTAYAAYGAR AARYTNTGYGARCARGCNTTYGGNMGNATGTTYACNTTYYTNGAYAARCAYYTNAGY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNAARCARAARYTNYTNAARACNACNACNGCNATHTCNCAYGCNGTNYTN TCNGAYTTYGAYTGGAARYTNCARYTNGCNYTNTCNAGYGAYAARATGTCNAGYYTNCAY CARCCNTTYYTNATGYTNGAYYTNGAYGTNMGNCARGCNGAYGGNGARMGNAARCARGTN ACNYTNGARYTNGAYAARGARGARYTNGCNAARYTNATHACNTCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY AGYGAYCAYTCNMGNTCNMGNMGNAARAARAARGARAARAARAARGCNMGNTCNMGNTCN AAYAGYTCNAGYGCNTCNAGYMGNCAYTCNAGYAGYMGNCAYAARAARTCNAARAARAAR CAY------TCNAGYMGNAARGCNTCNCCNAGYCCNGAYMGNCAYMGNCAYTAYMGNGAR MGNTCNMGNMGNTCNMGNTCNMGNTCNYTNGARMGNMGNACNTCNTCNMGN--------- MGNTCNMGNTCNCCN---GARGTNTCNMGNMGNMGNTCNMGNTCNCCNTCN--------- ---------------TAYTCNMGNGAYMGNMGNTCNMGNTCNGGNTCNMGNGGNCAYMGN TCNAARGGNCAYAAYCARMGNTCNMGNTCNAAYTCNMGNGGNCAYGAYAGYYTNMGNTCN TCNTCNMGNYTNGARMGNGARCAYTCNTCNACNMGNTAYGGNAGY--------------- ------------------CARGARMGNCAYAARTCNGAYCARGCNCAYGGNATGACNTCN TCNGARYTNGCNGARATGMGNATGMGNAARGCNYTNCARGCNGCNGCNYTNGCNGAYAAR AARYTNAARGGNYTNGGNGGNCAYGGNTCNCCNTCNAAYGGNTCNAGYAAYGGNCARGGN CARGAYTCNGCNYTNTCNMGNTCNCCNCAYATHCAYMGNGARTTYGCNGAYTCNGTNGCN ACNATHGARTCNGAYAGYTTYGTNCCNTCNGCNTTYAARTCNTCNMGNAAYAAYGTNAAR GARGAR---CCNGTNGAYCCNYTNATGTCNAGYCAYGAYGAYGCNATHTTYGGNTCNYTN TCNTCNATGGGNTTYACNATHAARCCNGAYYTNGAYAGYAARCCNGTNTCNATGGAYCCN GAYTCNATHATGCAYCCNAGYYTNTTYTGYAAYGTNGARGARAARATGGAYMGNTGGATH GARMGNYTNTCNCARYTNMGNMGNMGNAARYTNGARGGNGAYGTNATG------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GTNAAYAAYGCN GARGAYATGATHAARAARTGYAARGTNYTNATHTGYCARAAYGARATHCCNCARGAYATH TCNGTNGCNGCNATHMGNATHGCNAARAAYCAYGAYGTNAARGTNATHTAYAAYCCNGCN CCNGCNGCNGCNACNYTNAAYCCNGARYTNTTYTCNYTNCCNGAYTAYTTYTGYCCNAAY GARACNGARGCNCARATHYTNACNGARAAYCCNGTNAGYTCNGTNGARGAYGCNAARAAR GCNTGYAARATHYTN--------------------------------------------- ------------------------------------------------------------ ---------------------ATGTCNTTYCCNGGNMGNACNCCNATGGCNATGCCNGGN GGNATGCCNGGNATGGCNCCNMGNATGATG---ACNCCNGGNTAYGCNTTYACNTCNATG GGNATGACNMGNATGAAYCCNATGATGCCNATGCARATGGGNATGATGACNCCNATGATG CARCCNATGATGCARCCNCARATGCARATGCARCARCAR---CARCARCARYTNAARCAR AAYACNAARTTYGTNCCNCARGARATHCCNAARACNGAYACNAARGGNGARAARCCNCCN GTNACNACNGTNTTYGTNGGNAAYATHAGYGARMGNGCNCCNGAYATGATGATHAARCAR ATGYTNCARMGNTGYGGNAAYGTNYTNAGYTGGAARMGNGTNCARGGNGCNTCNGGNAAR YTNCARGCNTTYGGNTTYTGYGARTAYGARGAYCCNGARGCNACNYTNMGNTGYATHMGN YTNYTNAAYGAYTGGCCNATHTCNGGNAARGCNYTNGTNGTNAARGTNGAYGCNAARACN AARACNYTNYTNGAYGARTAYMGNAARAARAARCARGARACNGARGGNGTNACNGAYAAR AARGARTCNGAYGCNAGYGGNAARAARGARAAYGGNGARGARGARAAYGGNGARGARAAR GARAARACNGARGARTCNAARGGNGARGARGAYAARGARAGY---AARYTNGAYGARAAY ACNAARMGNGARGAYMGNGTNGCNCAYGCNGGNYTNGARGCNATHATGMGNGARTAYGCN TTYGARYTNGCNAARGARCCNACNAARTCNTCNGAYGGNGGNGAYCARGAYAARGARAAR CARYTNCCNAARAARGAYAARGARYTNTTYATGCAYGCNAARGAYACNGGNTTYGAYGAY ATGGARATGGARGAYGARAARMGNGARATHATHAAYMGNGARATHAAYAARTTYMGNGAY MGNCAYAARGAYGAYGAYGARGARAARGARAARGAYAAYMGNGARAARGARMGNAGYYTN GCNMGNGARMGNGARMGNMGNCARGARGARAARMGNCARMGNGARAARYTNGARAARYTN MGNGARCAR------------------MGNGARMGNGARMGN---------TCNTCNAAY ACNMGNGTNTCNMGNTCNAARTCNMGNTCNCARTCNCCNGTNGTNTCNMGNTCNMGNMGN MGNTCNMGNTCN------------MGNGARMGNAGYAGYMGNGAYMGNTCNMGNGARMGN MGNAARGARMGNGARATHGARGARGARGARGARYTNTAYGARMGNMGNAARYTNGARAAR AARYTNMGNGARAARGARGCNGCNTAYCARGARMGNYTNAARAAYTGGGARGGNMGNGAR MGNAARAARTCNMGNGARTAYGARAARGARAAYGARMGNGARGAYGAYMGNAARGTNGAR GARGGNMGNGARGCNMGNMGNYTNAARGARTTYYTNGARGAYTAYGAYGAYYTNMGNGAY GAYCCNAARTTYTAYAARGGNAGYGCNYTNCARMGNMGNCARAARGARMGNGARAARGAR AARGARYTNGAYAAYMGNGAYMGNCARMGNGARAARGARGARTTYGARGARATHAARMGN AARYTNTTYGAYGARGGNCAYCCNGAYGCNGARACNGARGTNGCNMGNATGGARMGNGAR MGNGARGARCAYYTNCARCCNMGNYTNCAYYTNCARGARYTNAARCARCCNCCNCARCCN CCNGGNCCNGARGARTTYGTNTCNGAYGARGARGCNTCNGGNGCNGCNGARGTN------ ---------MGNCARACNTCNCCNAARCARTCNGARTAYCARCARTCNMGNAAYGTNTCN AAYAAYGCNCAYTAYCARCARCAYATHACNGTN---------------CCNGARCARMGN CCNTCNCCNTCNYTNTCNACNTCNCCNATHTCNACNGAYTCNMGNGTN---AGYGCNCCN GGNYTNTGYATGGAYGARTCNTCNCARTCNTCNYTNCCNACNGTN------CCNCCNYTN TCN---TCNAAY---GARGARACNMGNYTNGGNACNMGN--------------------- ACNACNAGYYTNGCNCCNGGNGTNAGYCCNGAYTCNTCNAGYYTNCCNGGNGTNACNAAY GCNTCNGAYGGNAARMGNAARAARYTNACNGTNGGNGAYGTNTTYAAYCARGAYGAYGAY GAYAGYAAYGARCCNAARAARMGNAARYTNATHCCNYTNGAYTAYGAYGAYGAYAARTCN ACNCCNACNGARAARAARGGNGCNACNGCNGARGARAARMGNCARAARATHAARCARYTN ATHGARAAYATHCCNACNGCNAARGAYGARYTNTAYGCNTAYACNGTNGAYTGGGAYATH GTNGAYCARGGNYTNATGGAYAARMGNATHAARCCNTGGGTNACNAARAARATHGTNGAR TAYATHGGNGARGARGARCCNACNYTNACNGARTTYATHTGYCARAARGTNATHGCNMGN AGYACNCCNCARAGYATHCARAAYGAYGTNGCNATGATHYTNGAYGARGARGCNGARGTN TTYGTNGTNAARATGTGGMGNYTNYTNGTNTAYGARACNGARGCNAARAARATGGGNYTN GTNAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGGGNAAYTGYGTNCAYMGNTGYTTYGGNGTN ATHGAYMGNMGNAARMGNTAYYTNMGNTCNAARTAYATHACNGARCARAAYTTYTCNATH GARTTYCARAAYYTNATGGARGARGARCCNCARGAYGARATGTCNMGNYTNYTNACNGAY MGNGARMGNCARYTNYTNAGYTCNAARCARTTYTCNGCNYTNGCNCARGARCARACNCAR ATHGAYACNGARATHGAYGTNAARYTNAARCAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNGTNGTNTTYTTYAAYGGN GCNYTNGARAAYCARNNNATHAAYGARTGGATGTCNTAYCARYTNTCNCARMGNGAYAAR GTNMGNTAYGTNYTNMGNCAYATHGCNAAYAARGGNACNCCNCCNCCNAARATHTGGTGG AAYCARCCNGTNTTYYTNAARGARGCNYTNAARATGGCNYTNMGNCARYTNGGNGTNACN GTNGCNTGYTCNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AAYCCNCAR GCNGCNATGGARAARTAYAARGGNAAYACNGARGTNGARAARTTYYTNYTNGAYTTYTGY GGNYTNYTNGGNAAYCAYTTYACNGGNYTNGGNAGYAGYAAYACNAAYCCNGARTCNAGY CARCCNCCNAARGARTCNTCNCCNTCNACNATGACNGARTCNAARTCNCARAARGARAAR CCNTCNCCN------------------------------------------------GCN AARATHGTNGARYTNGGNAAYGGNGAYMGNAGYAAYGAYGARAARAARACN--------- ---CCNAARATHGTNGARYTNTCNGAYGARAAR---------------GAYAAYTCNACN AGYGCNATHGAYMGNYTNGGN---ACNGTNCCNAARGARAARTCNGGNTCNCAYATHMGN GTNCAYGAYCCNCARAAYGGNGCNGAYATHGARYTNCCNCCN---------------CCN ACNGAYGAYGARGARGTNAARGARGTNYTNAAYGAYCCNAARGTNATGGARACNYTNATG GAYCCNAARGTNATGGGNYTNATHAARACNYTNMGNGARGAYCCNGTNGARGGNCARMGN ATHGTNGAYAARGCNGAYCCNGGNYTNAARGAYAARATHMGNTTYYTNGTNTCNMGNGGN YTNYTNCARTTYCAR---------------------------AAYGTNCCNTCNYTNYTN YTNCARGAYCAYGARAAYGARATGYTNTTYCARACNYTNGGNMGNYTNTGYGTNACNYTN GCNACNGGNGTNGTNCARYTNTAYYTNGCNGAYCARACNGAYMGNACNMGNTGGAAYAAR MGNTGYTGYGGNGTNGCNTGYTTYGTNAARGAYAGYTCNAARAARTCNTTYTTYATHAAR GTNTAYGAYATHAARAARCARYTNYTNYTNTGGGARCARGARYTNTAYAAYCARTTYATG TAYAARACNCCNMGNGARTAYTTYCAYACNTTYGARGCNCAYGGNTGYCARGCNGGNATG AAYTTYGCNGAYGARGAYGARGCNCAYAARTTYAARAARGCNGTNGAYGGNAARYTNAAY GAYMGNMGNCARAARAARATHGARMGNMGNCARAARTCNGTNTCNCAYAARCAY------ ------------AAYGCNGAYCCNGGNTCNAAYCCNCCNCARMGNATG---GGNCARAAY GCNGCNCCNGCNACNCARACNGTNAARGTNGAYGCNAAYMGNGGNAAY------ACNAAY AAYCARAARAARGARAARGARAARAAYAARAARGAY---GCNAARAARAARYTNACNAAR GCNGAYATHGGNACNCCNTCNAAYTTYGTNCAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNGAYATHGCNGGNATGMGNAARCCNTAYAARGAYAAR CARGAYGTNTTYGAYGTNAARGAYTTYGTNTCNTCNGARCCNTTYCARCARTTYTCNGCN TGGTTYGARGARGCNAARGCNTGYCCNGGNATHATGGARGCNAAYGCNATGGCNYTNGCN ACNGCNGAYMGNGAYGGNMGNCCNTCNGTNMGNATGGTNYTNYTNAARGGNATGAGYAAR GARGGNTTYGAYTTYTAYACNAAYTAYYTNAGYMGNAARTCNCARGARYTNATGGARAAY CCNCARTGYAAYYTNATGTTYTAYTGGGARCCNYTNATGMGNTCNGTNMGNATHGARGGN AARGTNCAYAARYTNTCNAARGARCARTCNGARGARTAYTTYCAYTCNMGNCCNMGNTCN AGYCARATHGGNGCNTGYGTNAGY---CARMGNCARAGYTCNGCNGTNCCNTCNMGNGAR GTNYTNGAYAARMGNAAYGARGARYTNCARGCNYTNTAYGGNGAYGARAAYACNCCNATH CCNAARCCNGAYTAYTGGGGNGGNTTYMGNGTNGTNCCNCAYMGNTTYGARTTYTGGCAR GGNCARAGYAAYMGNATHCAYGAYMGNATHATHTTYMGNAARCCNGARGARGGNGARACN ATHGAYCCNACNGTNACNTTYCARGGNCAYGARGGNTGGGTNTAYGARMGNYTNCARCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GTNTCNTTYGGN AGYACNGTNYTNCAYGCNCCNGARTAYATHTTYGAYAARATHAAYGCNGCNTGYATGGCN ACNGGNYTNAAYGTNGTNTGGMGNTCNGAYMGNTCNTCNCCNGAYCCNAARMGNATHYTN ACNAARGARTGGATHCCNCARAAYGAYATGYTNGGNCAYGTNAAYACNAARYTNTTYATH TCNCAYTGYGGNAARAAYGGNCARTAYGARGCNYTNTAYCAYGGNGTNCCNATHYTNTGY YTNCCNATHTCNGTNGAYCARCCNTAYAAYTCNGARMGNATHMGNACNAARGGNTAYGGN YTNAARGCNGAYATGMGNTTYATHTCNCARGARGAYYTNACNGARYTNGTNAGYGARYTN ATHACNAAYACNACNTAYAARCAYAAYATHGTNAAYGCNTCNAARYTNTTYMGNYTNYTN TAYAARTCNCCNATGAARGARGCNGCNTTYTGGYTNGAYCAYGTNATGGARTAYGGNGGN GAYTAYATGMGNGCNTCNAGYCARAARATGCCNYTNTAYCARTTYYTNATGYTNGAYGTN YTNGCNGTNGTNTTYGCNGCNYTNTTYATHGTNTAYTAYYTNATHMGNTCNTGYGTN--- ---------CCNTTYCARAGYCAYTCNMGNGGNTTYMGNAAYMGNMGNACNGAYAAYAAR ACNAAYCARATHTCNACNGCNGARTCNCARGGNAAYTCNTTYTCNGTNYTNAARTCNACN GCNTTYGTNACNGGNGTNTGYAGYTGYAGYTTYGTNGGNGCNATGATHTGGAAYTAYGAR AAYGTNMGNCARGTNTAYAARGAYATGGCNACNGARAARCCNACNCCNCAYCAR------ MGNTTYTCNATGGARAARGCNYTNGGNTTYMGNCARCAYYTNAGYGCNATGTGGTCNMGN YTNGAYACNTCNACNAARYTNACNTTYGGNATHATHGCNATHAAYGCNGCNGTNTGGGCN YTNTGGAARGTNCCNMGNYTNCARCAYGGNATGGTNMGNTTYTTYTCNTCNTCNCCNGCN CAYCCNMGNTCNTCNATGGTNYTNAGYAGYTTYAGYCAYATHAGYTTYYTNCAYYTNGCN GTNAAYATGTAYGTNYTNYTNTCNTTYGCNCCNGTNGCNACNMGNYTNTTYGGNCAYGAR CARTTYTCNGCNTTYTAYATHAGYGCNGGNACNATHTCNGCNYTNGCNAGYATHYTNTGY CARCARYTNYTNMGNMGNCCNYTNGCNATHTCNGTNGGNGCNTCNGGNGCNATHATGGGN YTNYTNGGNGTNACNGGNATHGTNTAYCCNAAYGCNCARYTNCARATHGCNTTYGTNTCN GARATHATHCCNCAYTCNTTYTCNGCNGARACNGGNATHAARGCNATHATHYTNTTYGAY YTNYTNGGNYTNTTYYTNGGNTGGAARGTNYTNGAYCAYGCNGGNCAYYTNGGNGGNATG YTNTTYGGNATHYTNTAYGCNAARTAYGGNAGYAARYTNATHTGGGGNAAYMGNGAYTCN GTNGTNAARACNTGGCAYGAYATGMGNGGNAARCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGNGARMGNYTNCARCCNCCNGARGARGTNCCNACN GCNGCNGCNCCNAARGTNTCNACNAAR------CCNGCNCCNCAYATGGGNGTNCCNTTY MGNCCNCAYYTNGARCAYAARTGYACNGTNCCNGARCCNTTYGGNGTNGARCARCAYAGY MGNGARATGYTNAARAARAARGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CAYCARCAYGGNAGYGCNGAYGAYCCNCAYGGNGGNGTNCCNATGGGN ATHCCNAAYTCNTTYTGYGAYGAYGGNCAYAAYTAYACNTAYATHGAYTGGGAYCCNGCN TCNTCNGTNGARTAYACNTGYCARGAYGAY------ATHGAYYTNGGNGGNCCNACNTAY ---------ACNTAYGARCAYTGYGARCARGARTCNAARMGNCCNATHCAYATHTGYTAY CCNCARGARATHTCNTAYGCNGARGAYATHCCNACNAGYGGNCCNCAYMGNCCNYTNTGG CCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GARTAYGARCCNTTYGAYTCNGCNAAR AARAGYMGNATHGAYGAYGTNYTNATHCCNGAYYTNGAYGAYGCNGTNATHMGNATHGCN MGNATGMGNAARGCNCARGTNTCNAARTGYAARTGYGARGCNMGNAAYGTNGTNACNAAY TCNGTNAARTAYTAYAGYAAYGTN---------ACNGTNGARAGYGARCCNGTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CCNCCNGCNMGNTCNGCNGCNTCNYTNGTN GCNGTNGGNACNAARYTNTAYYTNTTYGGNGGNYTNAGYCAYATHTGYGGNTGGTTYGAY GAYGTNCAYGTNTTYGAYATHGTNACNAAYACNTGGTCNATHYTNGARACNGAYGGNTCN AARCCNMGNGCNMGNGAYAARYTNCARGCNGTNGCNATHGAYACNAAYATHTAYTAYTTY GGNGGNTTYGGNCCNYTNTCNGAYGARGCNGARGTNGAYGAYYTNGCNGGNGAYGAYGAY GAYGARTGYGARGAYGARGARGAYATHCCNGARAGYMGNGARCARGARGGNGCNAAYTTY GGNTGGTTYAAYGAYATHTGGGTNYTNGAYACNYTNACNYTNAARTGGTTYCARCCNATG CARATGAAYYTNGGNGTNCCNACNCARMGNGCNGCNCAYGGNATGTGYGCNGTNGGNMGN AAYYTNYTNATHTTYGGNGGNMGNGAYATHGARGAYMGNCARAAYGAYGTNCAYATHTTY AAYATHGAYTCNAARAARTGGGAYACNCARYTNCARATHAGYGGNCARCCNCCNGCNCCN MGNTCNTTYCAYAGYYTNACNACNGTNGGNGAYAARGTNGTNGTNTTYGGNGGNMGNGGN MGNGAYAAYAAYCAYTTYGAYGAYTTYGAYGTNYTNGAYYTNGARAAYAARAARTGGATH MGNTCNTCNGTNGARGGNTAYAARCCNCCNGCNMGNGGNCARCAYTGYGCNYTNACNGTN GGNGAYACNTTYYTNGTNTTYGGNGGNTCNGGNAAYTTYAGYCCNGARATHATGCARTGY CARTCNTTYTTYACNGAYACNTTYTTYGTNAARACNGAYGTNTTYTCNAARGARTGYAAR AARTCNAAYGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGYTNACNATHACNGAYTTYATHAAYATHYTNAARCARTAYTAYAARTCN GCNGARACNAARATHGARGARYTNGARGAYCAYAARATHGARACNTGGMGNGAYGTNYTN AARGGNAARCARAARCCNTTYGTNTCNATHGGNCCNGAYAGYAGYYTNTTYGARGCNGTN AARACNYTNGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY AGYMGNTCNTCNAARYTNTTYMGNCCNATGTCNGCNATGATGTCNACNMGNTTYGTNCAY GGNGCNATGATGGAYGGNGGNAARGARGARTCNGGNYTNGARGARAARGARGAYGTNTCN GAYGARGTNAARGCNGCNGARATGAARATGTTYGGNAARYTNACNMGNGARGARTTYGAR TGGCAYCCNGAYAARYTNYTNTGYMGNMGNTTYAAYGTNCCNAAYCCNTAYCCNGGNTCN GAYATHGTNGGNYTNCCNAAYGTNAARMGNGAYAARTAYTCNATHTTYGAYTTYYTNTCN ATHGGNGAYTAYCARMGNAARGAYGARATGGAYTCNAARGCNGGNTCNMGNMGNACNAAY AAYGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGGMGNCARYTNGGNGAR AARYTNTGGCARACNGTNGCNACNGCNYTNTCNTGYAARMGNYTNGCNCARCAYTCNMGN GTNGCNGAYGAYGGNTTYMGNTCNCCNCARGTNTCNATGYTNYTNGGNCAYGAYGGNMGN GTNYTNCAYGTNGAYAAYGGNATHAARTAYAGYTTYGAYGTNACNAARTGYATGTTYAGY TCNGGNAAYGTNACNGARAARYTNMGNGTNGCNAGYTGGGAYTGYTCNAAYGARACNGTN GTNGAYYTNTAYGCNGGNATHGGNTAYTTYACNYTNCCNTAYYTNGTNCAYGCNAAYGCN AAYCAYGTNCAYGCNTGYGARTGGAAYCCNGAYGCNGTNGCNGCNYTNMGNAAYAAYYTN GCNYTNAAYGGNGTNGARGAYMGNTGYTCNGTNCAYGCNGGNGAYAAYMGNMGNYTNAAR YTNTCNGGNGTNGCNGAYMGNGTNAAYYTNGGNYTNATHCCNAGYAGYGARGAYGGNTGG CCNGTNGCNGTNMGNGTNYTNAARGCNAGYGGNGGNGTNYTNCAYATHCAYGCNAAYGTN ACN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNTCNCAYACNACNGTNAGYAGYGARAAYCAYACNACNTCNACNYTNGCNTCNACN TGYTCNTAYAAYGARTTYGCNACNGGNYTNTCNMGNCCNAAYTGYMGNAGYAGYGTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARGCNYTNGCNYTNGTNTTYGCNTTYCARYTNGTNACNATGGTNYTNGAY TCNATHTTYGGNTTYAAYAGYTTYGCNACNYTNTAYTGYGTNTGYTAYAAYCARAARATH TAYCCNAAYATHCAYYTNTCNAAYGGNTGYGGNGTNGAYYTNGCNYTNTAYYTNYTNAGY GGNTGYATHYTNYTNYTNTCNACNATHACNYTNTTYGARTAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY TAYAAYGTNCCNTGYAGYGTNYTNGCNMGNAAYYTNYTNGGNCARCAYGTNGTNMGNTCN ATHGGNACNCARMGNATHAARGGNMGNATHGTNGARACNGARGCNTAYCARGGNTTYGAR GAYAARGCNGCNCAYAGYTAYCARGGNAARAARACNCCNMGNAAYGARGCNATGTTYATG AGYCCNGGNACNTGYTAYGTNTAYAAYATHTAYGGNATGTAYTGYTGYATGAAYATHTCN AGYCARGGNCAYGGNGCNGCNGTNYTNATHMGNGCNYTNGARCCNATHGARGGNCARGAY YTNATGAGYGARGGNMGNMGNAAYAARGARAAYAAR------AGYGCNAARCCNYTNAAR GARAARGAYYTNGCNAAYGGNCCNTCNAARYTNTGYCARGCNYTNCAYATHTCNAARAAY GAYTTYAAYAARGTNGAYYTNACNTCNTCNGAYACNYTNTGGYTNGARACNGGNGAYTGY GTNGAYGAYAGYYTNGTNGTNAGYTGYCCNMGNATHAAYATHGGNTAYGCNGARGAYTGG AARGARAARCCNYTNMGNTTYTAYATHYTNGGNAAYTCNTGYGTNAGYGTNAARGAYAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARGCNTCNYTNACNGGNMGNCCNMGNYTNYTNYTNACNGCNGCNGTNGCN GCNGGNAARAAYATHATHGAYTCNGGNTAYGAYGTNCCNYTNYTNAAYTCNAARYTNGAY TTYATHAGYYTNATGACNTAYGAYYTNCAYGGNTCNTGGGARAGYAARACNGGNCAYAAY AGYCCNYTNTAY---TCNGGNAGYTGGGARGAYGGNGAYGAYAARTTYYTNAAYGTNGAY TGGGCNGCNAAYTAYTGGGTNCARAARGGNGCNAGYMGNGAYAARYTNGTNATHGGNYTN TCNYTNTAYGCNMGNACNTTYMGNYTNYTNTCNACNTCNCAYACNGGNGTNGGNGCNCCN GTNYTNGGNGGNGGNAAYCCNGGNACNTAYACNMGNGARAGYGGNGTNYTNTCNTAYTAY GARGTNTGYGGNATGYTNAARGCNGGNGCNGCNAGYCAYTTYATHATHGGNCARMGNGTN CCNTAYYTNGTNCARGGNGAYCARTGGGTNGGNTAYGARGAYMGNCCNAGYYTNMGNGAR AARGTNMGNTAYATHMGNCARAAYAAYTAYGGNGGNGTNATGGTNTGGGAYACNAAYYTN GAYGAYATGAARGGNGAYTTYTGYGGNCARGGNACNTAYCCNYTNYTNACNGCNATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHYTN TCNCAYATGGCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GTN GTNGARTCNGTNGARGCNTCNMGNGARMGNYTNTAYGARCCNCCNTCNYTNGAYGAYCCN TTYGCNYTNMGNTTYAGYCCNTGGAAYGARGCNGTNCAYCCNGAYACNMGNMGNCARATG GTNCAYACNTCNAARAAR---GARGGNGAYACNTCNTCNGCNAAYCCNTCNGAYYTNGGN YTNTCNTGGATGGAYCCNACNCAYCCNCARATHTTYGCNACNGAYGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGGTNGARGCNGAYGTNTCN CCNGGNGAYGTNGAYCCNGAYATGAGYTCNGCNYTNCARAGYATHATGGARGARYTNATH GAYGARGTNTCNYTNGGNYTNTGYTTYGARATHCAYMGNTCNTGYAARATHGGNTCNTTY TTYYTNGAYGGNTGYGAYGAYAARTCNGAYACNGARTAYGCNATHATHGARMGNTCNGGN GTNGAYGTNYTNGGNCARGTNTCNTCNAARAARAAYTAYGARTGYGTNTGYCCNAAYTGY CARMGNCAYYTNGCNGCNTCNMGNTTYGCNCCNCAYYTNGARAARTGYATGGGNATGGGN MGNAAYTCNTCNMGNATHGCNAGYMGNMGNATHGCNAAYAAYCARAARCAYGGNAGYGAY GARAGYGGNCARGAYGAYGARAAYGAYAAYGAYTGGAAYTAYGCNCCNGARTCNAARMGN YTNMGNAARGTNAARAARGAYAARYTNGCNAAYTCNCCNMGNAAYMGNMGNYTNGCNAAR YTNMGNAAYAAYMGNAAYGGNGCNAAYGGNGARYTNCCNAAYGGNACNGCNACNACNGTN GCNGCNGCNGTNTCNACNACNACNCCNGCNACNTCNGCNACNACNACNGAYYTNCCN--- ---------------------GAYAGYCARGARCCNGCNCCNAAY---------TAYGAR ACNATGACNYTNGARGARMGNAARGCNYTNYTNYTNACNMGNTGYGGNGTNATHTCNGAR CAYACNAARAARATGTGYACNMGNTCNGGNAARTGYGCNCARCAYACNGAYGARCARMGN MGNCARGTNMGNCARTAYYTNYTNMGNCARAAYMGNAGYCAYGAYYTNGARGAYATHCAY ATHGAYATHGAYACNTAYGAYGAYGCNGARTCNCARTCNYTNMGNGARTCNYTNCARTGG GARGCNTCNTCNAAYTCNTCNCCNGCNGAYTCNACNTCNACNAAYAAYAGYACNACN--- ------------------------------AARACNTCNACNAARTCNTCNGCNAARCCN AGYAARAGYAARAARTCNAARGCNATHAARACNAGYGTNTCNAGYTCNAGYAGYGCNAGY AGYAAYAARGAYYTNGCNACNGTNAGYYTNTTYGAYTTY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ACNYTNATHCARAAYGGNGGNAAYGTNYTN GGNAGYYTNYTNTAYMGNATHCCNGTNTTYTCNACNGAYTTYTGYAGYCARYTNGTNGAR GARYTNTCNCAYTTYGARGAYAGYCCNTGYCCNAARGGNMGNCCNAAYACNATGTCNAAY TTYGGNATHTCNYTNGAYGARATGGGNYTNTAYGARGGNYTNATH---CCNYTNATHGTN GAYTAYATHCARCCNYTNTCNGAYGTNYTNTTYGGNCARTGGMGNMGNGARAARYTNGAY TCNTTYAARTCNTTYTCNGTNYTNTAYGGNCCNGGNAARGAYMGNGARYTNTCNATGCAY TTYGAYAAYGCNGARGTNACNYTNAAYATHTGYYTNTCNTCNGARTTYGAYGGNGGNGAR YTNGARTTYGGNAAYYTNTGGAAYGAYACNAAYACNCARYTNGCNAARGAR--------- ---ACNGTNAARCAYCARATHGGNACNGGNGTNYTNCAYYTNGGNCARCAYACNCAYMGN GCNYTNCCNATHATHTCNGGNTCNMGNTGYAAYYTNATHGTNTGGATGMGNAGYTCNGCN ATHMGNAAYGARGGNTGYAARATGTGYGGNYTNATHCCNGAYYTNGTNGARGTNCCNTTY GCNGGNGAYGGNTTYACNGTNACN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNMGNAAYTTYGCNATHMGNAGYACNTGGGAY GGNCARTGYTTYTGYCAYAAYCCNGTNGARATHTCNYTNGGNCARTCNGCNAGYGGNGAY YTNYTNYTNAARGTNGAYGCNCCNTTYTTYAAYAGYCCNGCNAARCCNGAYGGNCCNGCN GGNCARCCNTTYCCNCARYTNTGGGAYTAYGARGTNGTNGARGCNTTYTTYYTNAAYGAY CARAAYCARTAYYTNGARGTNGARYTNAGYCCNCAYGGNCARCAYYTNYTNYTNYTNYTN AAYGGNMGNMGNAAYATGGTNAARGAYAARYTNCCNYTNAAYTTYGTNGCNGCNATHCAY GGNGAYACNTGGACNGGNGARGCNATHATHCCNMGNGAYTAYYTNCCNCCNTCNGTNACN AARTTYAAYGCNTAYGCNATHCAYGGNGARGGNGAYGARMGNCARTAYGARTCNYTNTAY CCNGTN---------AAR---GARATGGARGGNATGCARCCNGAYTTYCAYMGNYTNGAR YTNTTYGARCCNYTNAAYATGAGYTCNATHYTNACNGAYTTYATHCCNTCNTTYACNTCN ACNYTNTGGGCNGARGTNYTNAARTCN--------------------------------- ---------------------------------YTNAARCAYYTNCARAAYGTNGTNGGN GGNAAYAARAAYGAYCARGARGARGGNMGNGARGARATHTGYGAYAAYGARAARACNGAR ACNGARCARGCNCCNAAYGCNACNGTNGTNACNTTYGCNTCNAAYGAYGARYTNTAYAGY AARATGMGNMGNCARMGNATHYTNMGNGARGARYTNMGNTCNAARAARAARGARYTNGAR GCNATHATGAARAARGAYMGNAAYAARMGNCARTAYTCNMGNAAYCARGAYAAYCARAGY GAYACNGTNTCNYTNAAYACNGAYACNTTYGGNATHCCNGCNAGYGTNGAYGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AAYTTYGAYCCNMGNAARMGN AAYTTYTCNGARGARGARYTNAARCCNCARCCNATHATGAARAARTCNAARAARATHTTY GTNCCNGARGAYYTNAARGAYGAYMGNTAYTGGGCNMGNMGNGTNAARAAYAAYTAYGCN GCNAARMGNTCNMGNGAYGCNMGNMGNGTNAARGARAAYCARATHGCNYTNMGNGCNGCN TAYYTNGARAARGARAAYAARTGYYTNAARGAYGARATGTCNAARYTNMGNAARGARAAY GCNAARYTNAARTCNGTNGTNGAYAARTAYGARGGNAGY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR AARCARGGNGTNTAYATHCCNGGNCARGGNCCNTAYGCNCAYGTNCCNCCNGGNTTYCCN GCNCARCARGTNYTNCARAAYGGNYTNGGNGCNMGNTAYACNCAYGGNCCNCARGCNTAY GCNGTNGTNTCNACNGCNGGNCAYCCNGCNTAYGCNTCNACNTCNATGCCNTAYCCNGGN YTNGCN------------------GGNATHCCNACNTCNAGYCAYGCNTAYYTNTCNGCN GCNCARTAYCARGCNAGYYTNAGYTAYCARGCNGCNGCNYTNGCNGGNMGNACNGCNCCN CCNCARCAYTAYAGYATGCCNACNCCNGTNCARGCNGGNGCNCCNYTNTTYGCNGCNGGN TAYACNCCNGTNCCN---GCNGGNATGGCNAGYCCNGGNGCNMGNTCNGTNCCNYTNGGN CARGTNGCNGCNTAYCCNCCNGGNTTYGCNTTYCCNGCNCCNTCNACNGARGGNAAYCCN CARATGGGN---------------------------------ATHGAYAARMGNTAYCCN ACNGGNCCNGGNGCNTAYGCNTTYGARTTYGGNGARCCNGCNGTNGARAARATHYTNGGN MGNGTNTGYCCNAAYTTYATGTAYMGNATHGARAGYGTNTGYACNAARGAYAGYCARGAR ATHACNGAYATHGAYMGNGARGAYATGYTNMGNGCNGTNGTNGAYGGNAAYGARGARYTN GTNYTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYACNGTNGGNGARTTYGTNTAYGTNAARYTNCAYTGYCCNTTYAAR MGNATGTGYGTNGARGCNGARAARGTNCARYTNGARATGCCNYTNMGNGAYTGYGARATH CCNGARGCNAARAGYMGNAAYCCNATHYTNAARAARATHGAYGAYCAYTTYGAYACNGAR AAYGAYGTNAGYGAYTTYGTNAGYGCNCARTTYYTNATGGAYAARATHCAYYTNTTYGAR GGNTAYGARGAYCCNACNAAYTTYTTYMGNCCNGCNGTNMGNTCNYTNYTNGTNCAYCAY ATGYTNATHAAYYTNGAYATHMGNACNATHCARGARATHAARGARGAYGARGCNAGYGAY GAYGARAAYGARGAYCCNAGYTGYTCNTGYTGYCCNGGNATHTGYMGNAAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGYTNTCNMGNTCNGGNMGNGCNGARACNMGNAGYMGNGCNAARGAR GAYATHAARMGNGTNATHAAYGCNATHGAYAARGTNMGNAARTGGGARAARAARTGGGTN ACNYTNGGNGAYACNTCNGTNACNATHYTNAARTGGGTNCCNGTNACNGCNCARGARAAY CCNGGNGCNYTNMGNAARATHCCNGGNGTNAARACNAARACNTAYTCNAARGCNMGNGTN GARMGNGARMGNGARYTNTAYGTNGCNGARACNAAYGGNCARCAYMGNGCNAAYTCNCCN GCNGAYTCN---AGYAAYAAYACNAAYGCNTCNAAYACNAGYTCNCCNTCNTCNMGNAAY CAY------AAYGGNGAYAARCCNAARAAYGGNAAYGTNACNAAYAGYCARGGNTCNGTN GTNTAYCCNGARGARAAYACNCARCARTCNATHGGNTCNTAYGGNTCNGARAAYYTNAAY GARGAYTCNAAYATGTCNTTYCCNGARAAYAGYGARYTNAGYGARCAYGCNGAYCAYAAY GARTTYTCNCAYGAYAGYAAYGAYGCNGAYCCNGGNATGMGNGTNGCNATGAGYATGGTN GGNGAYGARGAR------------------------------------------------ ------------------------------------------------------------ ATGTCNGAYAARCAYAAYTTYGGNGTNGCNCCNYTNACNTGYCAYGCNTTYAGYAARGAY MGNAAYGGNYTNGCNATGTCNYTNAAYGAYTCNAAYGTNAARATHTAYAAYAARTCNGGN AAYAARTGGGAYGARYTNGAYACNYTNAGYGARCAYGGNCARMGNGTNACNAGYATHGAY TGGGCNCCNAAYAGYAAYMGNATHGTNACNTGYTCNGCNGAYMGNAAYGCNTTYGTNTGG AARYTNGARGARGGNAARTGGMGNCARATGYTNGTNATHCCNMGNATHAAYMGNGCNGCN ACNTGYGTNMGNTGGTCNCCNAGYGARAAYAARTTYGCNGTNGGNAGYGGNTCNMGNYTN ATHGCNGTNTGYTAYTAYGAYAAYGARAAYAAYTGGTGGGTNAGYMGNCAYATHAARAAR CCNATHMGNTCNACNGTNACNTGYYTNGAYTGGCAYCCNAAYAAYGTNYTNYTNGCNGCN GGNTCNACNGAYTTYAARTGYMGNGTNTTYTCNGCNTAYCARAARGARGTNGAYACNAAR CCNTCNGCNTGYTCNTGGGGNTCNAARATGCCNTTYGGNGCNYTNATGGCNGARTTYAGY AAYGGNGGNGGNGGNTGGGTNCAYTCNGTNTCNTTYTCNCAYAAYGGNACNYTNGTNGCN TGGGTNGGNCAYGAYTCNAGYGTNTCNGTNGTNGAYTCNACNAAYGARAAYGCNYTNGTN ATHATHAARGARAGYTTYYTNCCNTTYATGAGYATHTCNTGGATHACNGARAAYTCNYTN GTNGCNGCNGGNTAYGAYTGYAAYCCNATGGTNTTYTCNTTYGGNGGNGGNAARATHACN AGYCARGGNMGNYTNGAYGTNCCNCARGARAARGARGCNGGNACNATGAGYGCNATGAAY MGNTTYMGNAAYYTNGAYMGNAARGCNACNACNAGYGAYAGYTCNTCNGAYATGAARACN CARCAYCARAAYACNATHACNCAYGTNTCNATHCAYACNGGNACNAARGARAAYGCNAGY AARATHGCNACNAGYGGNGTNGAYGGNAAYYTNATHATHTGGGAYYTNAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CAYTCN TCNACNTCNATHTTYYTNTTYTAYATGTGGMGNATHYTNGARGGNCARGCNYTNYTNCAR TAYTTYYTNATHCCNATHTTYYTNGAYAARGTNTGGGARTTYYTNAAYTAYACNCARTAY ATHYTNYTNGGNATHATHGTNGGNYTNTAYGTNGTNAGYYTNATHTAYGTNCARCAYGTN MGNACNGTNYTNAAYYTNCCNAARYTNATHGTNTTYGAYYTNGAYTAYACNYTNTGGCCN TTYTGGGTNGAYACNCAYGTNGAYCCNCCNTTYAARATGGGNTCNAAYGGNAARGTNTAY GAYTCNMGNAAYCARCAYGTNAARCAYTAYCCNGAYGTNCCNGARGTNYTNTCNAARYTN CAYTCNGARGGNTAYACNYTNGGNATHGCNTCNMGNACNGGNGCNATHCARGAYGCNACN GAYYTNATHMGNYTNTTYAAYTGGGAYAGYTTYTTYCARTAYMGNCARATHTTYCCNGGN TGYAARATHACNCAYTTYAARAARYTNCAYAGYYTNAGYGGNATHCCNTAYAARGAYATG ATHTTYTTYGAYGAYGARCAYMGNAAYATHCARGAYGTNTCNTCNYTNGGNGTNACNTGY ATGTTYGTNCCNGAYGCNGGNGTNACNCAYGAYTCNYTNMGNGARGGNTTYGARYTNTTY CARAGYMGNMGNTCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TCNGARAAYGAYYTNCCNMGNAAYGAYGARGAYCARATHATGGGNTCNGTNGCNTGG CARATHCCNATGGAYYTNCAYCCNAGYCARTGGAARGARCCNYTNCCNAARCARCARCCN YTNMGNGARGTNACNACNAAYAARCCNMGNAARCARAARCAYGCNAAYGCNTTYCAYMGN GTNGCNATGGGNGAYMGNAARGGNGGNCARGAYTAYTAYAAYGTNACNATHTGGACNAAR CCNAAYCAYCCNCCNGGNATHCCNAARYTNCARTGGGARAARGTNGTNAGYAGYGAYGCN YTNGCNAGYAARAGYAAYCAYTGGGARGTNGAYCCNYTNATGGAYMGNGTNCARTAYATH YTNAAYAARCARGAYGGNGAYCARAGYCARCARAGYGGNGAYGGNGAYAAYTAYAARAAR CCNATHCCNAARYTNTCNYTNCARGAYGCNTTYTAYTCNAARAARCARAAYTTYATHTCN AARTCNTCNGARMGNCARAARMGNATGAARYTNGCNAARGAYGAYMGNCAYYTNCARGAR TGYYTNMGNYTNGARMGNGARGCNATHTTYGCNGARCARGARMGNYTNGCNCCNCCNAAY YTNTAYGCNCAYCCNTAYAGYGAYAAYYTNTAYCARCCNAARCAYMGNATHYTNACNAAR CARGARATGAARACNYTNACNGCNMGNMGNTAYAAYAARYTNCCNGARGTNATHGARAAR AARGARGARGAYAARAARAARATHGARGCNMGNYTNAAYAARYTNMGNGCNAAYYTNTTY AAYAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARAARATGATGGGNCARYTN AGYYTNYTNAAYATGGCNTGYGCNGCNAARGCNMGNCARTGGTGYTCNGCNATHAAYTGY AARAAYAAYMGNTTYAGYAAYAGYGAYATHTCNTTYTTYMGNTTYCCNAARGAYGARGAR MGNTGYAARAARTGGGTNATHAAYTCNMGNMGNGARGAYYTNCAYAARAARACNGCNAAR GARYTNTTYAAYGGNAAYGTNYTNTGYGCNTAYCAYTTYGARGARTCNCARTTYACNTCN ------------AARAARAAYMGNYTNCCNTGYAARGCNATHCCNACNYTNTTYAAYGTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGAARGTNTAY CARTGYYTNATGTCNGGNGAYGARATGTTYACNGARACNACNCCNATGACNGARACNGAY GGNTTYTAYATHYTNAARGGNAARTTYGTNACN---AAR---GCNGAYGGNGTNGAYGAR AGYYTNYTNGGNGCNAAYCCNAGYGCNGARGARGCNGCNGARGGNACNGARGAYGGNACN ATGGARTCNGGNGTNGAYGTNATHATHTAYCARMGNYTNCARGARACNGGNTTYGGNTCN AARAARGAYTAYCARATHTAYATGAARGAYTAYATHAARAAYGTNTTYTCNAARYTNGCN GARAGYGGNAARTCNGCNGAYGARYTNGCNATGAARGARAAYGTNGCNATHGCNTTYAAR GARGCNTGYGCNAAYTTYAARGARTGGCARTTYTAYTCNGGNGCNAGYATGGAYCCNGAY GGNCAYATHGCNYTNGTNGAYTGGAARGAYGARGARGTNGAYGGNAARACNGTNAGYACN CCNTAYYTNTAYTTYTAYAARGCNGGNATHAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTNGTNGTNTTYYTNYTNYTN GTNAAYGTNGCNCCNGTNGCNATGACNTCNGAYCCNGGNGCNATGATGTGYGARMGNGTN TGYTGGGAYGARAAYACNYTNGCNGARCARTGYGARCARGAYAAYGGNTGYGAYGCNGGN ------GTNCARTCNAGYGAYGCNTAYATGCAYTGYATHGAYCCNTGYTAYGTNGARGCN GCNTCNTGYTTYATGATGTGYCAYACNAAYTTYCARMGNATHYTNAAYGTNTGYMGNGAR GTNTGYACNGAYACNACNTAYTCNCARTGYGCNAAYAAYTGYTTYATHGAYMGNGCNYTN MGNYTNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GCNAARAARGTNGAYATHGARAARGCNGARATGAAY TAYYTNATHGAYTGYGAYAAYGCNCARAARGARTTYGARGARAARMGNGTNACNYTNAAR GAYAGYYTNATHAAYCAYYTNAARGARAARAARGTNGAYYTNAARGARACNYTNATHACN GAYYTNAARGARAARMGNAGYATGATHGARYTNGARMGNCARACNGTNGAYYTNAAYGGN GCNGAYTTYATGGARGTNAARCCNACNATGACNMGNAARYTNMGNMGNMGNCCNAAYGAY CCNATHCCNATHCCNGARAARMGNMGNAARCCNTCNCCNGCNCARGTNAAYATHYTNYTN GGNGAYGAYCARATHATGTCNGAYYTNMGNYTNATHATGAARGTNAGYGGNAARCCNGTN GCNAARAARCAYGGNCCNGGNTCNCAYAGYCCNATHACNGARTCNTCNTCNGARGTNMGN ATHGARGARGGNMGNYTNTGGTAYGAYAARAARTGGTTYCARMGNAAYAGYATGGTNCAR ATHGAYAAYAARGARGGNGGNTCNMGNATHTAYGGNACNATHACNAAYATHGGNAAYCAR GARATHTGGGTNAARAARAGYGGNGAYAAYTCNAARYTNMGNATHTAYGTNTCNCARTTY CARMGNGGNAARTAYGTNATGAARAARMGNACNACN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GARGCNGARAARGARATHGARCCNCAR GARGAYGTNTCNAARGARCCNGCNGARYTNGAYGAYGTNGTNTCNGARGCNGARGARACN CCNGARATHATGGCNCARCARGARAARGAYGARGARGARATHGARAARGGNCCNACNCCN CCNTCNAAYTCNAARTCNTCNTCNAARACNAARTTYMGNCCNTAYMGNGGNAARYTNAAR TCNGCNGGNGTNAGYAARATGACNGARTCNYTNGARGARMGNGARATGCARATGATHTAY AAYGARATHGTNGCNTCNATGCCNCCNAGYGARGAYAARCCNAGYACNYTNTTYAAYATG CCNGCNTCNTGYACNAGYATHYTNAARGTNCARACNGGNMGNCCNCCNGGNAAYAARGAY GTNYTNTAYGAYGAYYTNGGNAAYGTNATHGCNGTNATGAARYTNGAYGCNGARAARYTN CCNACNCAYAARGTNAAYGTNAARTAYCAYGTNGTNGAYCCNGCNGTNGARGCNGCNCAR GCNMGNYTNGAYGCNATGMGNAARGGNAARTCNACNGGNAGYAARATGMGNAARYTNAAR TCNACNAARTCNYTNACNACNGARGCNGTNGCNACNGGNGCNAARAAYAARYTNCARATG GCNACNAGYACNGTNGCNCCNYTNCCNCCNCCNYTN------------------------ ---------------------------------ATHGARGARATGGARGTNTCNCAYGGN GTNATHATHMGNGARGGNGGNMGNGTNAARAARGGNCCNGGNMGNTAYTAYMGNAARYTN GAYGTNYTNGARGARCAYCARAARGGNATGAARCCNGTNAGYGTNMGNYTNAGYAAYTCN GGNATHACNGTNAAYGAYYTNYTNGAYMGNAAYACNCCNATHYTNMGNTCNATHGGNGAY TCNTCNCCNYTNCCNCCNATHGTNCCNAARCCNCCNCCNCARCCNCARTCNCARGTNTCN ATGYTNNNNATHGCNGTNATHGGNGCNGGNATHNNNGGNYTNAGYTCNGCNYTNAAYATH CARCARACNTTYCCNAAYGCNAARGTNNNNNNNATHGCNGAYNNNNNNGGNNNNGARACN GTNAGYNNNGGNGCNGGNGGNYTNTTYMGNCCNGAYNNNNNNCAYTTYNNNNNNGAYGAY AAYGCNNNNGTNATGAARCARTGYGTNMGNGAYTCNTGGNNNNNNNNNAGYGGNYTNGCN ATGTCNGARAANGCNAARGARAGYGGNCARNNNYTNNNNNNNGGNTGGNNNGTNNNNNNN NNNCCNAARGAYGCNGGNTAYGARGTNATGAARGANTGYACNTTYGAYTTYCAYNNNNNN ---NNNACNAGYGARYTNCARMGNMGNGGNATH---CCNTTYAARTAYGGNTAYTCNTGY ATHNNNGTNATHTCNCARNNNNNNATHTAYNNNGGNTGGYTNATGGARCARNNNAARYTN NNNGGNGGNGARGTNCARNNNMGNACNGTNAARNNNATHGARGARYTNTAYGGNGARTAY GARYTNGTNATHAAYTGYTGYGGNYTNMGNGCNYTNACNTTYYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARGCNTTYTCNGTNAAYAAYATHYTNGTNAARCAYATH------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGMGNTAYCAYACNGGNGARMGNCCNTTYATHTGYACNGCNTGY GGNAARGCNTTYATHGAYAAYTCNTCNYTNACNATHCAYATHMGNGTNCAYACNGGNGAR MGNCCNTAYAARTGYACNGTNTGYGCNAARACNTTYGAYTAYAAYTCNGAYYTNACNMGN CAYATGMGNGTNCAYACNGGNGTNMGNCCNTAYAARTGYACNGTNTGYGARAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGGCNGAYTCNAARTCN AGYYTNGCNMGNGAYGGNACNATGCARGTNACNGCNAARGARGGNATHGAYTAYYTNAAR TCNGCNCAYAARGAYACNYTNYTNAARYTNCARGGNYTNGTNAARGAYAARCCNGCNGTN CARMGNGAYGGNACNATGGTNTCNACNGCNAARGARGCNGAYMGNYTNYTNGAYGGNAAY AARCCNGAYGCNGAYGCNCARACNMGNGGNCARCARAARCARATHGAYGAYATHAARAAY GAYAARTCNGARCCNMGNGCNAARAARGCNAARYTNGCNAARGAYGGNACNATGGCNGTN ACNGCNAARGARGCNAARGCNYTNYTNGCNGGNGARAARYTNGGNGAYACNMGNCARGAR ACN---------AARAGYAARCCNAARACNCCNYTNAARAARAAYATGACNATGGCNMGN ACNYTNGARGARGCNAARAGYGTNYTNGAYGGNAAYYTNGAYGTNAAYGARGGNMGNAAR ACNMGNTCNCARAGYMGNGGNGAYCCNCCNAARCCNCCNGTNAARMGNGCNGGNACNATG ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGCCNAGYYTNCCN YTNATH------------AARCARAGYATGGCNGCNGTNGGNATGAAYACNGCNMGNACN YTN---------AARCARATGATGAARCCNCAYATHCCNATGATHAARTTYCCNMGNMGN GARACNCCNAARYTNTCNCAR---GCNGARCARATHGTNGGNAAYCCNAAYTCNCARGAY TCNGTNYTNATGAARAAYCCNGGNAAYGTNGCNACNCCNAGY---TTYACNGGNTCNAAR TCNMGNGGNCCNTCNATHGAYTCNTCNGARYTNGCNTTYMGNTTYAARMGNAARCCNATG TCNYTNGARGARATGGARTTYATHGARAARGGNGGNCCNGTN---ATGAARGTNGCNYTN GCNYTNYTNTGYYTNGCNGCNGCNACNGCNGTNGAYGAYGTNGGNMGNATHGGNATHTGY GCNGAYYTNTGYAGYATGAARYTNMGNTCNATHGGNGCNGGNCARTGYCCNAARGGNCAR GTNTGYGCNTCNAAYGGNTGYGGNCAYACNTGYCARACNGTNGTN---------GCNGTN ACNAARTCNAARTGYTCNAARTAYATGTGYYTNMGNTTYTGYGARAAYGGNTTYAARATH GGNTCNGAYGGNTGYCCNATHTGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GGNGAR GTNGTNYTNTGGACNAAYCAYMGNGTNATGGARTGGYTNMGNACNATHGAYYTNTCNGAR TAYGCNCCNAAYYTNMGNGGNAGYGGNGTNCAYGGNGCNYTNATGGTNTTYGARCCNMGN TTYAAYGCNGARYTNTTYGCNATHYTNYTNTCNATHCCNCCNAGYAARACNYTNYTNMGN MGNCAYYTNAAYTCNCAYTTYATHAAYYTNATHGGNCCNGARACNCARCARGGNAARMGN GARCARGARTCNCAR--------------------------------------------- ------------------------------------------------------------ ------------------------------ATHCAYACNCARGTNTCNCCNYTNYTNTTY CARGTNTCNGARAARYTNTGYGCNGARCCNATGAARAARMGNAARMGNYTNGAYCCNGGN YTNGCNGCNGCNAARACNCARAARAARATHAARAARATHGAYAARGARATHAARMGNYTN TCNMGNTTYGGNAARATHYTNAARCCNGTNGARGARATHGARGGNGAYMGNMGNAARYTN ATGGCNTCNGGNGARMGNMGNMGNGARCCNACNGTNYTNACNTTYGARGARTCNGARTCN MGNGCNYTNYTNCAYAARGAYTGGTCNGGNTAYMGNACNAARMGNTAYCAYGARATGYTN ACNGTNTTYTCNAARGTNGARGCNGCNCARCARGARGCNYTNAARGARYTNMGNGCNGAR TCNGARGARYTNTAYCARGCNGCNATHGARMGNGAYGAYCARYTNYTNCCNYTNAGYTTY GAYGGNCCNAARGARACNCCNCCNATHGARGCNTAYGARGCNCCNGAYGGNGARTAYGTN GAYACNACNMGNAARTTYATGGCNATGAGYGGNGARATGGARTGGAAYATHGAYATGGAR GTNAAYYTNTTYCAYGCNATGMGNGGNCAYAARCCNGCNGGNGTNAAYMGNCAYTTYCAR ATGATHGCNATHCAYGAYAARYTNAGYTCNTCNGCNAARAARATGACNTCNAGYGAYGTN TGGMGNCAYYTNTCNACNYTNTAYGAYYTNCARGCNYTNAAYGARTCNGARATHGTNCCN TTYCCNAAYAARATGGGNGAYTTYGCNYTNGCNGAYAARGARATGYTNGARYTNTGYGCN AARTCNTTYCCNMGNTCNTCNTAYATHAAYGCN---ATHTCNGAYTTYGCNAARGCNGAR GGNGGNGGNAARACNATHTCNAARYTNAGYAGYAARCCNGARCCNAARTCNGGNTCNCAR ACNCCNAARCCNGARTCNAARACNGARCAYAAR---CCNAGYAGYACNTCNAARGCNGAY MGNCARTCNACNACNCCNTCNAGYMGNTCNGARTCNAARTCNTCNCAY------------ ------------AGYAGYAGYAGYAAYACNTCNTCNCAYAGYTCNTCNTCNMGNGCNCCN TCNCCNTCNCCNAARMGNACNAARMGNACNMGNAAYGTNAAYGCNGCNTCNGCNAGYCCN TCNACNCCNACNGARCCNCARTCNAARMGNMGNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AAYCAYGARTGGTTYACNGGNAARAARMGNGARCAYGGNAAYGTNYTNAAR ATGATGAARGARTTYMGNGARGARCARGAR---GTNGARMGNACNGCNAARAAYGARAGY AGYATGAAYAGYGCNATHAAYGGNYTNGARGARGAYATHCCNTCNGARATHCCNAGYGCN ACNGCNAAYGGNACNGGNAARAARGARACNMGNAARGGNTCN------------------ ------------------------------------------------AARAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNAAYAARGTN YTNGCNACNAAYYTNGAYYTNTCNGARGARGCNAARGARMGNATHYTNMGNGARCAYGAR CARAAYATGCARTCNYTNTCNAAYCARYTNATGMGNAGYAARATHMGNCARCARAARAGY YTNGARATHAARYTNAAYCARMGNAARGCNAARYTNGCNGARYTNAARCARAARMGNGCN GARATGGGNGARGCNMGNCCNGAYAGYAGYAARAARGARAARGCNAAYATHGARACNAGY ------YTNGAYCARCARATHGCNAARGARGARGARGGNTTYGARGARGCNMGNYTNTCN GCNGTNGCNGARYTNMGNMGNCARYTNTCNCARGARACNGARGAYGCNYTNAARCARCAR GAYGARGARATHGGNYTNYTNATHGGNMGNYTNCARGTNGGNCARGCNMGNMGNAARGCN GTNYTNGARAARCARGAYGCNGTNYTNAARGAYYTNCARGAYAAYYTNGARMGNCARGTN ACNTCNGCNAGYGGNYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGAYATHYTNTAYATHTCNGTNTGYYTNGCNTTYYTNACNTGYCCNTCNTTYGGNCAR GAY------GTNTAYGARGTNACNTTYGGNAAYGARACNCARTTYGAYGTNTCNGARGGN GCNGARYTNGTNAARTTYACNTGYGARGTNACNGGNGARGGNYTNAAYGTNTTYACNCAY CCNGTNGARAAYCCN------------GTNTCNAARGAR------------------GAR YTNGTNATGTCNAARAAYGARGCNYTNGARGAYGGNAARCCNGARTTYTAYGCNGCNAAR GCNATHATHACNAGYGARATHAAYTCNAARTTYGCNYTNGTNTTYACNATHYTNAARGTN MGNCAYCARGAYGAYGGNACNTTYGGNTGYMGN---------TAYMGNGAYAARAARACN GAR------------------YTNGARGTNGTNGTNCAYMGNTCNYTNGAYGCNYTNAAR GTNAARTTYGGNGAYAARGARCCNGTNTCNGTNACNCCNGARGAY------------CCN ATHGTNATHGAYCCNGGNAARTAYTCNGTNAGYTGYATHGCNGARGGNAGYAAYCCNGCN ACNAARGARGTNCAYYTNTTYTTYAAYGGNATGATGGTN---GARCAYGGNGARCCNGTN ATHACNCARATGGARACNCCNGARMGNAARTTYMGNACNACNYTNACNGCNGAYGTNAAY ATHATGGTNAARGAYTCNGGNAARGARTTYGAYTGYCARGCNAAR------GAYTCNCAR GGNYTNGCNTCNTCNACNAARYTNGGNATHGAYGTNACNATHTAYGAYCCNGARGTNTTY TGYAAYGAYACNACNGCNTTYCAYGGNCARGCNAAYCCNATHATHTCNTGYACNGTNAAY CAYACNAAYYTNGARGTNACNGGNTAYGCNTAYCARATHGGNGARACNGGNGARATHATH AARCARGGNGAYCARCAYGAY---------AARAAYATHCARGTNYTNGTNTCNGAYGTN GCNCCNGGNGTNTCNATHGTNTCNYTNGAYYTNCAYAARGCNMGNCCNGARTAYYTNGAY AARGAYTAYTAYATHYTNATHGAYYTNGARGGNGGNCAYACNAGYAARGARAGYGTNMGN YTNCAYAGYGTNATHGGN---------------------GAYAAYCCNGGNGAYGAYGCN ACNMGNATH--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNTTYTTYGGNGGNAAYTAY GCNYTNYTNTCNYTNAAYYTNGAYCCNAAYCCNGAYTAYTTYYTNTCNGTNYTNCAYAAR MGNYTNATHGARGGNCCNGTNTTYGAYGCNACNGTNCARCCNAGYACNGAYGARYTNMGN ATHTAYGCNCAYTGY---ACNMGNGARTTYGGNYTNTAYAARAARGGNGCNATHACNYTN GCNTTYYTNAAYACNAARAARGAYAAYGTNACNGTNAGYYTNGGNCARTTYTCNGCNTCN TAYGTNGAYYTNTAYATHYTNACNCCNGGNGAYTCNGCNGGNYTNAARTCNMGNTTYGTN AARYTNAAYGGNGARACNYTNAARATGTCNGGNTCNTCNYTNCCNGCNYTNAARCCNAAR YTNCAYAARGGNGAYATHACNTTYCCNGCNYTNTCNTTYGGNTTYGTNGTNGTNTCNGGN GCNAARGTNCCNYTNTGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GCNCCNGTNGAYATHAGYAGYYTNYTNAGYAAYYTNATHAAR GCNGGNYTNATHAARGAYGGNAARACNGCNGAYGCNATGCCN------------------ ---------------AAYGTNTCNGGNTCNAGYTCNGARAAYGARATGCCNAARCCNCAR CCNAARTTYGTNAARAARMGNAARGAYATHCCNATHYTNTCNGAYTTYGAYACNGAYMGN ATGAARATHGTNTAYAARMGNGTNATHGARGARYTNCAYGARGGNATHCARTGYCAYACN TGYTCNGCNMGNTTYACNGCNGAYGAYCARGARAARTAYMGNGCNCAYYTNGAYTGGCAY TTYMGNCARAAYAARYTNGARCARGARATGGTNAARGTNGCNAARAAYMGNAARTGGTTY TAYACNATHGCNGAYTGGATHCARTAYGARGARYTNGARGAYYTNGARGARACNTCNMGN AGYGARATHTTYGARCARATGMGNYTNGGNAGYGARCARTCNGGNGCNGGNATGYTNGGN YTNGAYTCNYTNMGNYTNMGNGCNYTNGARGGNAARGAYTAYATHAARAAYCCNGTNGCN TCNGGNGTNGARGGNGARGAYGTNTGYGCNACNTGYGGNGAYCCNTTYGAYCARATGTGG AAYGARGARACNGARGARTGGATHYTNAARAAYACNATHAARGTNGAYGGNAARACNTAY CAYCCNATHTGYTTYGARGAYYTNCARGARACNCCNACNCCNGTNGCNGAYATH---CAR AAYCCNYTNGAYCAYGARATHTCNTCNCAYATGGAYCARCCNTCNGAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GARGARGAYGARGAY GAYGTNGAYGARTTYACNGARGARGARATHGCNAAYGAYCCNATHAARMGNATHYTNTGG GCNTCNGARAAYAAYAARYTNGAYATHGTNACNGARYTNATGMGNACNAAYCCNGARYTN GTNTCNGTNTGYGAYAGYGAYGGNTAYACNCCNYTNCAYMGNTGYTCNTAYAAYAAYCAY CCNGAYGTNGCNAARYTNYTNATHTCNCAYCARGCNAGYGTNCAYGCNAARACNGTNGAY GGNTGGCAYCCNYTNCAYAGYGCNGCNMGNTGGAAYTCNGTNGARACNGCNCARYTNYTN ATHYTNAGYGGNGCNGAYATHAAYGCNCARACNAAYGGNGGNYTNACNCCNYTNCAYATG GCNGCNTCNGARYTNGAYAAYGGNCARATGYTNGARYTNYTNYTNAAYAAYCCNTTYATH AAYACNACNATHGTNTCNMGNGTNGGNGARACNGCNAARCARATHTGYCARMGNACNAGY CCNCAYCAYCAYYTNTTYGARYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNYTNTCNYTNGAYTCN YTNYTNGTNYTNYTNMGNAGYCARGAYCARTCNGAYATHCAYYTNAAYTCNCAYGTNAAR CARGTNYTNGARYTNATHYTNACNGAYGARAARMGNAAYTAYATHTTYGARGARGCNGTN AAYYTNYTNTGYGARATHTAYATHTCNYTNYTNAARGARMGNAARACNAAYAGYACNMGN CARATHAGYCARAARGGNCARAARTTYTCNYTNCCNCARGGNAAYGGNCAYTTYTCNCCN MGNTAYGGNTGGYTNGAYCARYTNCCNCCNTTYTAYGGNTCNGARGARATGYTNMGNCCN TGYMGNAAYYTNTAYATGAARMGNGTNYTNAGYCARGGNACNMGNATGAAYTCNAARCCN ATHTCNATHTCNCCNAARCCNGAYGARAARATHGARTGYCCNTGYTGYYTNTGYAAYGAR AAYYTNYTNAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CAYGCN GTNTAYAGYAAYTTYAARYTNGARGGNGARMGNGAYMGNTAYMGNYTNCAYGTNTCNGGN TTYTCNGGNAGYGCNAARGAYTCNYTNAAYMGNCAYAAYAAYAARCCNTTYTCNACNGAR GAYMGNGAYAAYGAYAAYMGNMGNGAYGCNAAYTGYGCNGTNGARTGGGARGCNGGNTGG TGGTTYGAYAARTGYTGGTTYGCNYTNYTNAAYGGNCCNTAYCARAGYGAYGTNMGNTAY AARGGNATHGCNTGGAARAGY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARACNATHACNGTNCCNGGNCAYYTNCCNTGYYTNACN TCNYTNACNACNGTNAARGCNATHAARGGNYTNYTNYTNYTNACNGCNTCNTGGMGNGTN GARGARATGGGNGAYTGYGGNGGNGTNATHGTNYTNAAYCCNGTNACNGGNCARGTNTAY AARACNGTNGTNTGYAAYATHCCNAAYGCNGGNTGGMGNMGNTCNGARAARGCNMGNGAR GARAARAAYCAYGTNTAYGCNGTNAGYAGYTCNGGNTCNGTNTCNTGGTGGAAYAGYMGN AAYGGNAAYATHGTNGGNTAYMGNCARTCNAAYATHGCNACN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNMGNGGNGTNAGYYTNAAYAAYTGYGGNTAYATHGTNACNGAYACNGTNYTNACNCAR YTNGCNAARAAYATHCCNAARYTNGARCARYTNAAYYTNAGYMGNTGYGCNCAYYTNACN GAYAARTGYYTNCCNATHYTNTCNAARMGNYTNCCNAAYYTNAARGTNYTNCAYATHGCN GGNGTNCCNTCNATHAARCARACNTCNGTNCAYACNTTYYTNAAYTCNGCNAARGARYTN ACNTTYYTNGAYGTNTAYTAYATGAARACNACNMGNGARGARTAYGAYTCNYTNATGCAR MGNGCNAARGAYTGYGGNGTNGARYTNATHYTNMGNCCNCCNMGNCAYGGNMGNGGNGAY AAYYTNGARAAYGARGAYACNGARGAYTCNAGYGGNGAR--------------------- GARGGNGAYGAYGAYGARGARGARGARGARGAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNCCNTAYYTNGGNAGY AARATHAGYYTNATHTCNAARGCNGARATHMGNTAYGARGGNACNYTNTAYACNATHGAY CCNAAYGARGCNACNGTNGCNYTNGCNAARGTNMGNTCNTTYGGNACNGARGAYMGNCCN ACNGAYMGNCCNYTNCCNGCNMGNAAYGARGTNTTYGARTTYATHATHTTYMGNGGNCAY GAYATHAARGAYYTNCAYGTNTGYGARCCNCCNAARCAYTGYCAYACNGARGGNGGNGTN CCNCCNGAYCCNGCNATHGTNAARTCNTCNCARCCNCCNCCNGGNCCNGCNGGNGCNGCN TTYCAYGGN---CCNCCNGCNGGNGGNTTYGCNGGNGGNCCNTCNTAYCARCCNTTYACN CARCCNATG---TTYTAYAAYCARGGNCARCCNGCNCCNGGNTAYCCN---CCNCCNCAY CAYGGNCARCCNGGNTCNCARGARGARATHTCNTCNATGGTNGARCARTCNCCNGARCAR ATHACNCAYCCNTCNGTNACNGCNATHGGNACNMGNCCNATHTCNGGNTCNCARAGYTCN ACNCCNCCNYTNAGYMGNAARTCNCCNACNTCNGAYCARGGNGTNCARGTNCARCCNMGN AGYCCNGARAARTCNAGYAAYGARAAYCARCARAARCARGTNCCNTCNCAYCARCAYCAY CARCAYCAYCARCAYCCNMGNGGNCARGGNGGNATGMGN---CAYGTNGGNCAYAAYAGY GGNGGNCARMGNGAYMGNGGNGAYAAYMGNAAYGAYGGNMGNGCNACNGAYCCNMGNGGN GARMGNAAYGTNACN---TCNTTYGTNMGNGGNMGNGGNGGNAAYMGNGGNCARCAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYTAYCCNGCNGARGTNGARGTNTCN TAYGARGARTTYGARAAYGTNAARCAYYTNYTNCCNMGNTCNACNGTNCCNGARGTNCCN CARCAYCCNTCNTAYCCNACNCCNTCNGGNTGGATGCCNCCNAAYGAYGARATHMGNTCN CARCARCCNTAYYTNGTNMGNMGNACNAARAAYCAYGTNYTNCCNGTNTAYCCNGARCAR MGNGARGTNTGGAGYMGNATHATGCAYCAYGAYATHGTNAARAAYATHGARGGNGAYATH TGGACNYTNGARTCNGARYTNMGNMGNTTYYTNCARGAYAARAAYCARGARGAYAARATH ATHACNCARGTNCAYGARGTNAGYMGNTGYATHMGNATHMGNGGNCARCAYMGNGCNGAY ATHGCNCARTTYYTNATGGAYAARGGNATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TAYAAYCAYAAYAGYTCNGTNTTYATHYTNCAYTTYCARGGNTCNCCN CAYYTNATHATHAGYAAYACNMGNGTNAARGARGCNACNGCNYTNACNGARTCNYTNGTN CAYGTNTTYAAYGCNCARAGYYTNTCNTAYATGCARYTNTCNGAYMGNCAYGTNTTYTCN YTNGCNGAYATHGCNYTNMGNAAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARATGGAYTGYYTNATHCCNYTNCARCAYCAYATHAAYAARYTNGTNYTNGTNGGN GAYCARGCNCARYTNCCNGCNACNGTNYTNTCNCARGARGCNMGNGAYAAYMGNYTNGAY MGNTCNYTNTTYGARMGNYTNCAYTCNAARTTY---------TCNTAYAAYGARAAYYTN GTNATGATGYTNAARGARCARTAYMGNATGCAYCCNGARATHGTNAARYTNCCNAAYGCN TAYTTYTAYGAYAAYCARYTNACNACNGCNGARTCNTGYGTNAARTCNMGNACNTCNCAY YTNMGNCCNTAYYTNGTNTTYGAYGTNGTNGAYAGYATGGARTGYGGNAGYCAYMGNAGY TCNAARTCNAAYYTNAAYGARGCNAARTGYGTNGTNTCNYTNTGYAARYTNGTNGTNGAY GTNYTNTCNCAYTCNAARAARAAYAGYGGNGGNCARMGNCARMGNAARATHGGNGTNATH TGYCCNTAYTCNGAYCARMGNTCNYTNATHGGNAARAARYTNAAYGAYGTNGGNYTNTCN AAYATHGCNGTNAAYACNGTNGAYAGYTTYCARGGNCARGARAARGAYGTNATHATHATG TCNTGYGTNMGNGCNCAYGARAAYCCNCARTCNGTNGGNTTYATHGAYGAYAGYAARMGN ATGAAYGTNGCNYTNACNMGNGCNMGNYTNGCNCAYTAYATHATHGGNAAYTAYMGNACN YTNMGNACNTCNGAYYTNTGGTCNTAYYTNTAYCARGAYGCNAARGARMGNAAYYTNYTN ATHACNGTNAAYAARACNGARMGNTTYAARCARATGGCN------------GGNAARAAR MGNMGNMGNACNTTYGARYTNGARGARCCNACNYTNAARGGNGAYGGNACNCCNACNATH GARAAYGAYCARCCNMGNACNMGNYTNAARACNTCNMGNAAYTCNACNCCNCARAGYGAR ACNCARGGNCARCCNGTN---AARMGNYTNMGNMGNGGNACNTTYGAYAARAAYTCNCCN ------GCNCCNCARGAYAAY------------AARTCNTCNGTNCCNGAYAGYAGYCCN AGYACNYTNGCNATHATHGAYTCNATHCARGGNGAYTGYTCNAGYGCNGARMGNAARCAR AARYTNATGTCNGCNATHGAYAARAARGTNCARYTNAARATGGCNTCNAGYCCNTCNAAY CAYATHAARTCNCARCCNAGYCARATHCCNMGNTTYATGGCNTTYYTNAAYAARAARAAR ---GARAAYCARAAYACNYTNACNCCNGGNAAYAARGAYTGGAAYAARATHCAYAARAAR GARTTYTCNAARTTYGAYTCNATHGAYGTNTAYYTNGARAARMGNGTNCARMGNAARAAY AAYYTNTCNGCNAGYGGNAARAARCARYTNCCNAARAARTTYCCNGCNGTNCARAARTCN TCNGCNMGNATHGTNAARCCNGTNCARAARGARACNGTNTCNTCNAARATHTTYAARCCN ACNATHATHTCNACNAARAAYATHAAYTTYGAYTTYTCNAARATG---GCNTCNGAYTCN AGYAARACNCCN---------------------------------AARGCNAARGCNGTN AAYACNCCNTCNMGNAARAAYGTNCCNACNTCNACNAARAAYAGYGTNTCNACNAAYMGN GCNACNCCNTAYAARTTYACNGGNAAYACN---------ACNTCNYTNAAYACNACNGTN ACNTCNTCNAARAARGCNGCNTTYGAYYTNAARGCNAGYYTNGCNMGNCCNYTNACNTGG AARCCNCAYACNGGNAARYTNCAYACNGTNGAYTTYAAYATHGGNAARTCNTCNAGYGTN ACNACNACNACNACNACNAGYAGYAARCCNMGNAARGTNGTNAGYMGNGAYAAY---GCN AGYAARATGMGNCCNYTNCARGCNAARGAYATHMGNMGNGCNGCNCAYYTNGAYMGNMGN ACNAAYCARAARTAYGTNGAYATGATGAARMGNMGNGGNYTNATGGCNTTYGTNTAYGAY CAYGGNMGNCCNCAYTGGTCNCARGGNGGNCCNYTNTTYTAYCCNGCNCCNCARATGAAY AAYTTYCCNAAYCCNCCNATHCARGGNCCNTCNCCNCARTGGYTNMGNGGNCCNYTNATH GGNGGNCCNGGNCCNAAYCARCARCARTTYGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGNNNTTY GGNTCNAARTAYGTNTAYYTNGGNAAYNNNNNNGARGAYGARGARGARGTNAARGTNNNN GARNNNGAYGAYGTNGTNYTNTCNGAYAGYGAYGTNAGYGAYGAYGAYGGNGARACNTGY YTNYTNGAYATHYTNGAYACNGCNGGNCARGARGARTAYTCNTCNYTNAARGAYCARTAY GTNMGNAGYGGNAAYGGNTTYGTNATHATHTAYAGYATHATHGAYCARGARAGYTTYAAR GARGCNGARGCNNNNTAYMGNTGGYTNAARMGNATGAAR---GARGAYGAYTGYCAYGTN ATHYTNGTNGCNAAYAARCARGAYYTN------AARGCNGARGCNACNGTNAGYACNCAR GARGGNCARGAYYTNGCNGGNMGNYTNGGNGTNCCNTTYNNNGARACNTCNGCNYTNGAY GGNTCNGGNGTNACNAAYGCNATGAARGGNYTNGTNMGNATHATHCCNMGNGCNAGYAAY GAYTAYAARATHGTNATGYTNGGNAGYGGNGCNGTNGGNAARTCNAGYATHACNATHMGN TTYGTNAAYGAYACNTTYGTNGAYGAYTAYGAYCCNACNATHGARGAYTCNTAYMGNAAR ATGATHAAYGTNGAYGGNYTNCARGCNGTNAGYAARGAYACNMGNAARGCNGCNAARAAR GCNAARAARGCNAARAARAARACN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNYTNTTYGGNACNYTNTAYCCNGCNTAYGCNTCNTAYAARGCNGTNMGN ACNAARAAYGTNAARGARTAYGTNAARTGGATGATGTAYTGGATHGTNTTYGCNYTNTTY TGYTGYGTNGARACNTTYTCNGAYGTNTTYYTNTCNTGGYTNCCNTTYTAYTAYGARYTN AARATHGTNTTYGTNATHTGGATGYTNTCNCCNYTNACNCARGGNTCNAGYTTYATHTTY AARAARTTYGTNCAYCCNCARYTNGCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AARAGY CCNYTNTTYAAYGARTTYCCNMGNAARMGNTCNYTNGTNGAYATGCCNGTNGTNACNACN YTNTAYTAYTGYTCNYTNTAYCAYTTYGAYYTNTCNGARAAYTCNYTNGGNTGYCCNGCN GCNATHMGNAARMGNCAYCARATHTCNGARAARCARTAYGTNTGGACNGCNGTNGCNGCN MGNGCNAARYTNAARCARTGGAARGAYATHGAYTCNATHYTNACNACNAARGGNTGGTTY GGNGGNACNAARATGAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GCNTCNACNTTYAAYAAYTCNMGNMGNTTYTGYTCNYTNTCNTGYTCNMGNMGNCAYAAY GTNAGYCAYACNMGNMGNGTNGGNYTNTTYAARTCNAARGGNTCNTCNMGNAARMGNAAR CARATGATGGTNGGNMGNAARGGNTGGMGNTCNTCNMGNGGNGGNMGNYTNCCNTAYTCN ATGAAYAAR---AAYATGGAYGARACNACNAARGAYCCNAAYGAYGTN---CCNCAYGGN GAYGARATGAGYAGYTCNAAYAGYACNCARGAYACNAGYTCNTCNGCNGCNTCNCCNCAY TCNGTNCCNGARTAYAAYATGGARGTNGAR---GGNAAYTTYCCNGTNACNGAYCCNGCN AARTGGACNGTNACNGARGTNTAYGAYTTYGTNYTNAAYYTNCCNGGNTGYTCNGAYTAY GCNGARGAYTTYMGNTCNCARGARATHGAYGGNCARGCNYTNYTNYTNYTN--------- ------------------------------------------------------------ ---------------------------TTYCAYACNGCNAGYGTNTCNAAYGTNAAYCAY MGNAARGARMGNGCNATHGTNAARCAYYTNTAYTAYMGNAAYCAYGARAAYAGYYTNAAR CAYTCNTAYAGYCCNATHGTNGARYTNCCNGAYTAYACNTAYATHGAYGGNMGNCCNACN GARATGACNYTNTCNTAYAARGARAARCARGARAARAAYGAYAAYYTNGCNAARCARGTN GTNAARYTNGTNAAYGARGTNAARTTYGCNMGNAGYGARYTNTCNMGNCARCARGARGCN AARGCNCARTAYGARYTNAAYMGNAARAARGGNGGNYTNAARGARAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGTCNATHGARYTNGTNTCNAARTGYYTNGAYYTNGGN------GAYCAYACNACNATH ACNAGYACNAARGGNAARAARAARAARAARCCNAARACNAAYGAYGCNATGCARGTNATH AARACNGAYMGNCAYGGNGTNTGGAARGARYTNMGNAARGTNMGNAARCARCARYTNAAR GARATHACNAARAARAARAARAARGARAARTTYAARTCNGCNATHGARATHTAYAARGAR GTNCAYGAYGTNGAYTAYACNGAYMGNAAYGTNGARACNYTNYTNAARGTNTCNAARYTN GGNAARGTNAARGARGGNGAYGCNMGNAARATHYTNTAYCARCARCCNTGYMGNYTNTCN MGNGAYATHCARGARAARGARGARGCNCCNGARCCNACNTCNATHTTYACNGARGARGAY TTY---------------------------------------ATGTCN------GTNCCN CAYGCN------------CCN---CCNYTNGGNGGNGGNAAYCARCARGAYMGNCARAAY MGNAARYTNYTNYTNGARCAYATHCARGARCARAARAARMGNYTNCARCAYGGNCAYCAY TCNTCNTCNAGYAGYCCN---ACNCCNTCNATGAGYACNAGYCCNGCNACNATHYTNAGY AAY---CCNTCNTCNGTNCCNGGNYTNACNGCNGCNGARTAYGCNACNATHAGYAAYCCN CARCARMGNGCNGCNYTNCARCAYGCNCAYGTNAAYTCNGTNGGNTTYTTYATHACNCAR GAYTCNTCNTTYGGNAAYYTNATHYTNCCNGTNYTNCCNMGNGTNCCNGAYGTNAARACN GARACNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CARCCNYTNGARTGY TCNTCNYTNACNTCNGTNGCNTTYAAYYTNTTYAAYAAYATHTGGAAYACNAAYTAYATH TAYTGGTAYCCNTAYAGYGAYGCNGAYGCNAAYTTYATGTCNMGNTTYCARATHCAYTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GCNGGNATGYTN GCNGAYCCNGTNAARATHGCNAARGARMGNGARMGNGARGARMGNGTNMGNCARGCNMGN GARMGNYTNGARGGNGARMGNAARAARAARYTNGARGARYTNAARGARCARCARMGNYTN GCNCARGARAAYMGNGARMGNCARYTNGARATGMGNMGNCARAARATHGARGAYYTNMGN MGNMGNGAYACNGARMGNMGNGCNGCNGTNGARGARMGNMGNMGNATGAARGARGARATH GARMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATHGGNTCNAAYGGNCARGTNYTNGARTCNCARTCNCCNTGGMGN YTNTCNTTYATHACNGARGCNTTYTGGGGNYTNATHAAYTTYATHGTNYTNTTYTTYCAR ACNATGTTYAAYCCNGAYAARAAYGCNAARGGNGAYAARTAYTCNACNGAYTAYMGNAAR CCNGGNGGNGGNGGNCCNCCNACNMGNMGNATGGGNGGNTTY------MGNMGNGGNGGN GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CARCCNCARYTNYTNACNMGNCAYAAYGTNGTN CCNGGNATGTTYYTNATHTAYGCNGAYGGNMGNYTNYTNTTYTGYGAYCAYATHTTYAAY GGNTAYGGNAAYACNAARACNGAYTTYMGNAARCARGTNATGAARTCNMGNCAYGAYTTY ATHCAYGGNTTYTCNYTNCCNCARGAYTTYMGNTTYAGYCCNTCNMGNGGNATGYTNGGN CCNMGNGCNCCNTGGGGNGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GCNAGYAGYTGYGGNMGNYTNTCNCCN ATHCAYGCNGTNGCNGARCCNGAYYTNCAYGAYAAYCARGTNCCNCCNATGTCNCCNAGY YTNTGGAAYACNGAYATGAAYCARTCNCCNACNYTNTAYCCNGGNGAYTGYTAYTCNGAY YTNGTNGAYTCNYTNGGNGAYGGNATGAARYTNTCNTCNCCNGARAGYATGAAYATHATG AGYAAYATHMGNGAYCCNTAYATHTCNGGN------------------------------ ------------------------------------------------------------ ---------------------------------------------------GAYGTNMGN AAYAAYGTNGCNGTNCAYATGGGNACNGCNCAYCCNCAYTTYGARAARGAYGGNACNGTN YTNTAYTAYGGNACNAAYATGGAYTAYMGNAARGCNTAYAAYATHGTNMGNGCNTCNYTN CCNGCNAAYAAYGARGCNCCNATGAARGAYGCNGARATHATHGCNAGYATHCCNAGYMGN TGGAARATGAAYATHGGNTAYAAYCAYTCNTTYGGNATGTCNGARAAYTAYATHGTNGTN ATGGARYTNCCNGTNACNATHAAYYTNYTNAARATHATHACNYTNTCNATGMGNTCNGAY ATHTCNAGYGCNATGGAYACNCAYCCNGAYGARAARATHYTNATHCAYGTNGTNGARAAR AARACNGGNAARCAYYTNCCNGTNACNTTYMGNGCNCCNCAYGGNTTYGTNTTYCAYTTY ATHAAYTGYTAYGARGARGARAAYCAYYTNATHGTNGAYGTNTGYYTNTCNGAY------ ---MGNTTYGTNGTNAARGAYYTNGAYATGAARTTYYTNGCNAGYAAYGAYGARTCNTCN AAYTTYGCNMGNTTYGTNYTNCCNYTNAAYGTNGAYGGNGCNCARATHGGNGARAAYGTN AAYCAYYTNCCNGGNAGYCARGCNAARGCNGTNATG---TTYAGYAARACNATHGTNGAR GTNGARGCNGARGCNATGTTYGGNACNAARYTNAARTTYGAYGTNCCNMGNATHAAYTAY GAYYTNAAYGGNGTNAARTAYMGNTAYYTNTAYGGNGCNACNYTNYTNACNCAYTCNGAY AARAARGTNYTNAARYTNGAYGTNGTNGAYAARACNGTNAARGARTGGAAYTGYGGNGAY GAYTAYGARCCNGGNGARCCNGTNTTYATHCCNCAYCCNGAYGCNAGYGARGARGAYGAY GGNGTNGTNYTNTGYCCNATHGTNTCNACNGTNGCNGARYTNGARTCNTAYYTNYTNATH YTNGAYGCNTCNACNTTYAARGARYTNGCNACNGCNTTYGTNCCNACNGAYATHAARATG AGYYTNTCNTTYCAYGGNTCNTTY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GCNGCNTCNGCNATG GTNACNACNGCNATHYTNTTYYTNYTNCAYYTNYTNAAYYTNACNCCNMGNATHCCNGGN CCNTGGYTNYTNATHGARTTYYTNTAYTAYTGYGTNTAYTGYATHYTNATHATHATHGCN GCNATHGTNTGYGCNGTNMGNGCNCAYTAYTCNGAYGCNATHGGNGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GCNAARMGNAARAARCAYACNGARAARCARGCNGARTCNTTYCARAGYMGN ATGAARGAYAARTTYAAYGAYMGNCARYTNGARAARGAYYTNTGGACNGCNCARAARGCN TGYYTNCARYTNGAYCARCARGCNGGNYTNYTNGARCCNTCNGARCCNTTYTTYTGGCCN GCNAAYAGYYTNCCNATHCARTCNGARAARMGNGAYGARGARACNATHGARCCNTCNAAY AGYCCNTAYGAYGAYGCNTAYAAYAAYCAYCCNTAYGARGARTCNGARGAYGAYYTNGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AAYATH ACNYTNYTNCCNGTNGAYGTNATHGTNAAYGCNGCNAAYTAYMGNYTNAAYACNGGNGGN GTNGCNAARGTNATHGCNAARGCNGCNAARYTNMGNGARGARTGYGARAARTAYATHTCN AAYTAYACNAARATHGAYGTNACNGARCAYTTYGCNTCNAGYGGNGGNAAYYTNAAYGCN AARCARGTNTAYCAYGCNGTNGGNCCNAARTTYTCNTTYTAYAARACNMGNMGNGAYGAY TGYAARCARGAYYTNMGNYTNACNATHYTNAARTGYYTNTGYCAYGCNGARGCNCARGGN TAYMGNTCNATHGCNTTYCCNTCNATHAGYGCNTCNYTNTTYCARGTNCCNAARGARATH TGYGTNGARAGYTAYATGAARGCNGTNCARCAYTTYGARMGNATHMGNAAYCAYCAYAAR YTNGARGARGTNTAYTTYGTNGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GTN ATHAAYCCNGGNAARTAYCARATHGARACNTGYMGNTGYYTNYTNTCNGCNGCNCAYTCN GAYACNGARTCNGGNYTNGCNACNAARGARCARGTNMGNAARGCNGTNAARAAYYTNAAR AAYYTNAAYMGNGTNTTYAARYTNACNGAYAGYAAYAAYACNAARTCNGTNGAYAARAAR GARYTNMGNYTNYTNTTYCARATHYTNGARTAYTAYGTNAAYGARGAYGTNGTNAAYGCN ATHATGACNMGNTAYGGNGARMGNCARGGNCAYYTNGGNYTNGARGAYTTYATHCAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CAYTGYTTYATHGTNGTNCARCCN ATHCAYAARGARGGNGARGCNGTNMGNTAYCARATHTCNGTNGCNGCNMGNMGNGAYGTN CCNMGNTTYTAYCCNCARYTNCCNCARCCNGCNGARTTYTCNAARGGNGARGARTTYMGN GARTTYYTNYTNACNAARYTNATHAAYGCNGARYTNGCNTGYTAYAARGCNGAYCARTTY GCNAARYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGAYCAYCARTAYGGNATHGCNGTN ACNAAYAARTTYGCNYTNTTYATHGAYGARGAYGARGAYCCNTTYGAYGCNGTNTCN--- ---------------AARAAYAARGGNAARAARGAYGCNGARAARAARACNAARTTYAAR CARAARAARATHACNCCNGTNGTNGARGARAARCCNGCNGCNCCNGARAAYGARGGNGCN AARAARAARGARGGNGGNGAYAARCCNGTN---TCNMGNCARAAYGAYMGNGGNAARGGN AGYGCNMGNAGYMGNGARCCNMGNGARYTNMGNGARAAYGAYGGNGAYAARMGNCCNCCN MGNMGNCARGGN------------------------------------------------ ------CCNMGNGARAAYAARGAYGGNMGNGTNGGNGAYGARAAYGTNCCNCCNGARTTY MGNGARMGNCCN---GAR---GGNTTYAARMGNMGNGARGAYMGN---GARGGNAGYGGN TTYGCNGGNGGNGARMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNGGNMGNGGN GGNGARMGNGGNGGNAGYACNGGN---GGNAGYACNGGNGGNTTYGGNCCNMGNGGNGAY MGNAARMGNGARTTYGAYMGNCAYAGYGGNACNGAYMGNACNGGNATHAARCCNGTNGAR AARAARGARGGNGGNGGNGCNCAYAAYTGGGGNAGYTTYMGNGAYGAYATHGARGARCAY GGNCARGTNAAYGCNTCNGARGARTCNACNGARTGGGGNAAYCARCARGAR--------- AARCCNGGNGARYTNAAYGARAGYGTNGARGCNGAYAAYGTNACNGARGARGARGCNCAR CCNCARCARATGACNYTNGAYGARTGGAARGCNYTNCARACN---CARGCNAARCCNAAR CCNGARTTYAAYATHMGNCARGCNGGNGARGGNGTNGAYTCNGGNCARTGGAARAARGGN GTNGARTAYCARAARAARCARGARGCNTCNGAYCARGARGAYGAYTAYGARGARGGNGAR CAYAGYGAYCAYCAYAGYMGN---------------AARCARYTNGTNACNGAYATHMGN ATHACNTTYAAYGAYAAYCCNMGNMGNGGNMGNGGNMGN---MGNGGNGGNMGNGGNGGN ATGGARMGNGGNGGNGGNGGNGGNCCNGGN------GGNMGNGGNGGNMGN------GGN AGYGCNMGNGGNTTYGGNGGNAAYAARAARGARGCNGCNCCNMGNTTYGAYGAYGARTCN GAYTTYCCNTCNYTNYTNAARACNGCNGCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNCAYGTNMGNTAYAARAAYAGYAARCARMGNATHAARGAYGCNAARGTNCAR GTNGARAARAGYATGMGNTAYATHAARAARAAR---------AARTCNMGNCAR---CCN AGYAGYYTNAGYGGNAARAGYACNATH---YTNGCNGARAARCCNGTNGAYAAYGTNTGG GTNMGNAARTTYTAYCCNAARCCNMGNTTYTCNATHGARGARGCNGTNAAYMGNCAYCAR GCNTTYGCNCARCCNGCNATGYTNGAYAAYATGGAYGGNYTNGTNTAYYTNGAYATGCAR YTNGAYTTYMGNACNAARAARCARACNAARTTYATGAARAAYATHAARTCNACNYTNYTN YTNCCNTTYCCNTTYACNTGGGGNACNCCNCCNTCNATHYTNGTNTTYTGYAARGARGAR GARCAYACNAAYYTNGCNYTNTCNYTNGGNGCNMGNCARGCNGGNTCNCCNGCNGARATH ATHAARATGGTNGARAAYGGNGTNYTNAAYCCNAARGAYTTYGARCAYGTNYTNGCNACN GCNGAYTGYGCNGCNGAYATHACNCCNGCNMGNTCNTAYTTYMGNGAYAARTTYCCNCAR MGNGCNAARGGNAAYYTNGGNACNGAYYTNAAYGCNATGTGGACNYTNTTYTAYACNGGN TAYACNTAYGARTCNCARAAYGTNACNGARGCNGARGGNAARYTNCARGTNCCNYTNGGN CARYTNAARCARCCNACNAGYCARYTNGTNGCNAAYTTYGARGCNTAYATHGARTCNGTN TGYAARCAYMGNAGYATHGCNYTNGGNCCNTTYATHCCNTCNATGAGYGTNGTNGCNCCN CCNTCNCCNGARGARTTYATHGTNCARGTNGARGAYTAYGTNCCNGGNTAYAARAAYGAR GARGTNGAYTCNGAYGAYGARGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CARTTYTCNAGYATHGGNTCN YTNGGNGCNAAYCARGAYATHTGGYTNYTNGGNGARTTYGGNCARTCNYTNTCNCARTGY AARAARACNATGTCNAGYTCNATHCCNGCNTCNAARYTNCAYYTNATHTTYCCNTCNATG AAYAAYATHMGNYTNAGYYTNGARGGNTAYAAYGGNGGNGGNTGYGTNCCNTAYAGYATH AARACNGCNTCNAARCARCCNTGGYTNACNCCNTTYTTYAGYCARTGGAARTCNGARGGN MGNGGNMGNTCNGGNGCNGTNCCNCAYATHAARTCNTAYACNMGNTGYTCNCCNGAYGGN TCNCARGCNGCNTGGTTYGTNGTNACNAGYGCNAAYYTNTCNAARGCNGCNTGGGGNTCN YTNGARAARAARGGNAGYCARYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARAARTCNGTNGARYTNTTYTAYGAYGTNGTNTCNCCNTAYTCNTGGTTYGCN TTYGARGTNATGTGYMGNTAYCARAGYMGNTGGAAYATHAAYYTNAARYTNMGNCCNTTY TTYYTNGGNGGNGTNATGCARGCNTCNGGNAAYMGNCCNCCNGCNATGGTNCCNAAYAAR GGNAARTAYAGYTTYATHGAYGTNCARMGNTGYAGYCARTAYTTYGAYGTNCCNYTNATH ATHCCNCARAAYCCNTTYGARYTNATGTTYGARAARGGNACNYTNAARGCNCARMGNTTY YTNATHGCNYTNGAYATGAARTGYCCNGARAARGTNGARGCNGTNTCNMGNGARTTYTGG ATGMGNGGNTGGAAYMGNGAYGARGAYYTNTCNGAYGAYGARAGYATHGCNGARGCNGCN AAYAARGCNGGNYTNAAYCARGARGAYATHAARTTYYTNYTNTCNMGNGTNCARGAYAAR GARGTNAARGAYMGNYTNAARAGYACNACNGAYGARGCNATGGARYTNGGNGCNTTYGGN TCNCCNATGGTNGTNGTNGAYGTNAAYGGNAARAARGARATGATHTTYGGNAGYGAYMGN TTYCCNATHYTNGCNCARATHYTNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CCNGCNAAYCCNTAYAAYCCNTAYATHACNACNTCNATGCCNGCNCAYTCNGTNGCNATG ACNACNAAYGGNGAYGCNAAYTCNCCNATHATHTCNCARGCNYTNCARCAYACNATGATH CCNGCNACNCCNAARGCNGTNMGNGCNGAYAARTTYGARGCNTCNCARGARAAYGGNGAR TGYYTNGCNTCNCAYTCNCCNYTNYTNGAYACNTTYAAYATHCCNACNTAYYTN---GCN CARAGYTCNGTNCCNGGNATHGTNCCNGCNTAYAARMGNATHGCNGTNGGNGAYGCNATH GGNAARGGNGGNATHCCNTTYTAYCCNAGYAGYCAYYTNATGTCNCCNTAYCARCARCAR GCNCAYTCNYTNGTNCCNYTNCARCARCAYCCNTCNTAYATHCCNATGCCNTAYCAYYTN TCNTAYAAYCARCCNYTNGCNGGNCAYCCNCCNAGYGTNCCNMGNTTY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNCAYCCNYTNTGYCARATHCARGCNGTNTGYGARAAYGARAARCARMGNAAYYTN AARAARACNATHAARAARTCNTGYYTNGARATGYTNGGNTAYYTNMGNCCNGARGTNGAY YTNCARAARGTNMGNCAYAARGARTGGGARGGNAARGTNYTNACNMGNGARCARGGNYTN TTYTAYGGNYTNATHAGYYTNATHCCNATGAGYGTNGAYMGNYTNACNACNATHGAYTAY AGYACNGAYGARTAYATHAAYGAYTTYCCNGARATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CARGTNCARCARGCNTCNYTNMGNYTNGCNTAYCCNGTNTCNAGYGGNTCN CAYCAYMGNGCNAGYGARTCNGARTGGGTNCCNGTNGAR------------------MGN ACNACNGCNCCNGCNACNACNACNGTNAAYAARGTNACNAAYTCNYTNCCNCCNTCNGAR CARCCNGARCCNCCNACNAGYATHTTYCCNGCNTCNAGYGAYAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNAAYATHACNGTNAARGARACNATG ACNGCNGTNYTNCCNTGYGARGTNACNAAYYTNGGNYTNCAYAARGTNGTNTGGACNGAY GARYTNTCNACNYTNYTNACNTAYCARGARMGNMGNGTNGTNGAYGAYATGMGNATHAGY ATHGARMGNCCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TTYAGYMGNCCNCCN AAYACNTTYATHCAYCCNATHMGNATHATGTGGTCNGAYACNGAYTTYAAYGCNCAYTGY AAYATHGGNAGYTAYGCNMGNTTYGCNGAYGAYGCNYTNMGNACNGCNYTNMGNYTNAAR ACNCCNTCNCARCAYTCNCCNATGAAYYTNTCNAGYGARAARAARGAY---GGNAGYCCN TCNGCNGCNYTNAARGGNATHTCNCARMGNGTNATHAARGARGGNGTNAARCAYTTYAAR ATHAAYTTYTTYCARGARTGYCAYGARGGNCARATGYTNAAYGTNCAYATHTGGCARGAY GGNGTNAARGAYACNGTNGTNTAYTGYTCNATHGARMGN--------------------- ------------YTNAARCARTTYCCNAARATHGCNGAYATHCCNGAYYTNATGAARGTN TTYMGNACNGCNTGGTTYGARAARYTNAARGARGTNMGNMGNGTNGARAARMGNGAYGAR GARTAYATGAARGARATGTTYMGNCARGTNTTYATGGARTCNGTNTAYCCNGTNCAYAAY YTNTCNACNYTNTCNTCNTAYMGNATGGGNGAYGARGAYAAYGAYMGNATHMGNCARGAR AAYYTNYTNMGNTAYAGYGARGTNMGNMGNACNAAYAARAGYGCNYTNGCNGCNYTNYTN TCNCCNAAYYTNACNTTYCARCCNTTYYTNYTNGARGARGTNGCNTAYTCNGTNATHGGN CCNAAYTGYGTNAGYAARTCNCCNACNGCNYTNGTNGTNCARGCNGARGARYTNGGNTGY GARGGNAARGTNGARGARGCNCARGGNGTNATGAARYTNGTNGAYCARYTNAARGARGAR MGNCAYCARATGGAR------ATH---CCNTCNCARGARGAY---GGNCCNYTNATGAAR CARATGGARGTNTGYGAYGTNTGYGGNGCNTTYYTNATHGTNGGNGAYGCNCCNCARMGN CARGAYGARCAYYTNATGGGNAARCARCAYGCNGGNTAYGCNCARGTNMGNGCNGARATH GARMGNMGNAARCARAARGTNAARGAYGARACNGARGCNMGNGARGCNAAYGARAAYAAR YTNMGNGTNGARMGNGARGARMGNGAYAARGARMGNCARMGNGARMGNGAYGARMGNMGN CARAARGAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGAYTTYGAY TCNTCNTCNAARTTYATHGCNTCNYTNGCNMGNTTYYTNCARTCNYTNTGYAAYGGNTAY GTNGARTTYGAYAARGGNGTNGARGTNATHGGNCAYATHTAYYTNAGYGTNGAYAGYGAY ACNGGNMGNAARATHGAYTAYGTNYTNAAYGARAARGTNTGYAARAAYGAYAAYTCNGTN ACNTTYATHAGYAAYAGYTTYCAYGCNCARCCNGCNGARAARCCNAARGCNATHCCNAAR AARTCNGAYTCNGARAAYMGNAAYGARGAYTCNGTNGTNATGGAYGAYTCNGGNMGNTCN GTNCCNAAYAGYACNAAYGTNGGNACNATGGGNTCN---------------TCNCARGAY MGNTCN------------AAYAARMGNCCNMGNTCNCCNTTYCARMGNMGN--------- ------------ATGGGNGTNGGNGGNGCNTCNCCNMGNTAYCAYGARTCN---GGNCAR GCNAARTCNGCNCAYACNGAYATHCCNCCNTCNGGNAAYAAYYTNAAYAGYGGNGARGAY TAYGAYGGNGAYGGNTTYCAYGGNGGNGAYGARGAYAGYCARAAYTAYCCNTCNAAYTTY YTNAGYCARGAY---TAYTCNAAYTCNGARATHGAYCARAARCCNGTNATHGARCCNGAY ATHAGYATHGTNAARGARGARTAYATGTCNAGYCARCARAGYGGNTCNTCNTAYYTNGGN AGYAGYCARCCNACNGGNCCNGGNMGNGGNGCNCCNAGYTCNTCNCARTCNTCNTCNTAY CCNATGATGCAYCARAAY---------------------------TCNTCNTAYTCNCCN GGNGAYTAYTCNGGNTCNTCNATHGARCCNMGNGAYCCNTCNGARYTNACNMGNGCNCAR CARGARGARYTNGARATGTAYTAYMGNAARGGNACNGAYCARCAYYTNACNTTYYTNMGN AAYATGMGNGARGCNCAYGCNATGTAYCCNTTYACNGGNAARMGNGAYAARGARYTNTTY GAYAARGCNYTNGCNGARTTYYTNGAYCAYYTNCCNATHTTY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CCNYTNTCNTCNAGYAARCCNYTNACNCAYGTNACNAAR AGYMGNCCNAARCCNCCNAARTGYGTNMGNCCNACNMGNCCNATHYTNGAYACNGGNACN ACNGARATHGAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AGYGGNTCNAARGTNGTNCAY ATHTGYACNCAYCCNATHTCNMGNYTNCCNACNCCNGTNCAYGGNATGCCNAGYCCNGAR CCNTCNGTNATGAARAAYGTNGAYTTYYTNTAYTTYGARGARTGYGCNGGNYTNATHGCN TAYTTYGCNGGNATHCAYATGAARAARAARYTNCCNAGYTTYATHATHGTNGARGAYATH YTNTCNTAYGCNTCNCARMGNCARGAYAARCCNGTNGARAARACNYTNGCNATGYTNYTN GCNYTNATHTCNAAYGCNTGYACNTGG--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNATHCARATHAARACN GCNGAYGARAARGARGTNCARMGNMGNATHGAYTCNTTYATHMGNAAYAARMGNAAYGAR GTNAAYGARMGNAAYATHMGNGARTTYATHTCNCCNTTYGGNTCNGAYCCNATHAAYAGY TGYGCNMGNGTNGARGCNGTNTAYGTNCAYMGNGARGGNATGAARAGYCAYATHAAYYTN AARAAYGTNGARAAYGCNTAYGGNCCNCARACNMGNYTNMGNCCNGAYACNAGYGARGAR ACNCCNTCNTGGATGAARTCNGCNGAYGTNCARMGNGCNGARGCNGTNGARGARMGNYTN YTNAAYATGGARTCNCAYYTNAAYATHGGNAAYAAYGGNGGNGAYATHTAYMGNMGNATH AARTCNYTNGARGARMGNATHAGYTTYYTNGARGGNATHTCNCCNGARTAYTTYTCNAAY GGNYTNCCNCCNACNAARCARMGNAAR------------------------------ATH GTNCCNACNAARCARACNAGYGCNGARATHGCNGGNCAYCCNACNGAYATHGTNGTNAAY AARTTYGARGAYCAYYTNTTYATHATHGCNACNCARTAYCARAARYTNGGNACNGTNATH GARGTNTCNMGNGARGTNATHAGYGAYGARGTNCARGGNCAYATHCCNATGTTYTCNACN AAYGTNYTNYTNGGNAARGAYGARCCNYTNACNCAYGTNATGGCNAARACNATHGTNACN TCNYTNAAYCCNCCNATGCCNGTNATHYTNACNYTNGCNYTNAARGTNACNACNCCNGAY GCNGTNCARGCNATHATHGARYTNATHAARTCNTGYYTNATGGCNACNAAYATHCAYTTY GARGCNMGNMGNMGNCARMGNGTNGTNGAYAARGCNTGYAARGCNMGNAARGARATGGCN YTNYTNGCNCARAGYTCNGAYGGNGTNGCNCCNTCNGCNCARAAYGCNACNAARCCNGAY ACNATHATGTGYACNGAYCARGGNCARTTYTAYCARACNMGNCCNAGYGTNCAYGTNTGG ACNGGNCCNGARMGNAAYMGNMGNACNTAYGAYCARAGYMGNGARGGNCCNATHYTNGGN ACNTCNMGNMGNCARYTNCARMGNGARATGAAYTTYMGNGARAARAGYYTNAGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGCCNAAR TTYTAYGARGAYGTNGARGAYAARAGYAGYCAYAARAARATGGCNTGYGARGGNATHMGN GAYGAYYTNYTNGARTGYYTNYTNAARAGYGAYTGYTGYAARMGNGAYAARAAYACNCCN MGNGARTGYATG---------AGYAARGTNGGNGAYCCNTCNGTNCCNGAYGARTGYCAY AARYTNMGNATHGCNTTYYTNGARTGYMGNMGNTCNATGYTNGAYATGMGNACNMGNTTY MGNGGNMGNAARGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AAYGAYMGNTCNAARAARAAYGCNGTNCARGCNAARATHAAYMGNGARAARAARAARGCN TAYATHAARAGYYTNGARGAYGARATHAAYGCNYTNAARAGYGAYAAYACNAARYTNGCN TCNGARAAYACNMGNATGCARCARTCNACNGCNGAYYTNCARGARGARGTNGARTAYYTN AARTCNGTNYTNATHAAYTCNAGYCCNYTNTCNGAYYTNYTNAARAAYATHTCNAAYGTN AARGARGTNAARYTNTCNGCNACNATHGTNGGNAARAARMGN------TCNGCNGARGAY GAYCAYAAYTAYAAYATHTTYGARAGYGTNCCNGARAARMGNGCNMGNMGNATHAAYGAR AAYYTNMGNAARGCNGGNGTNTGYYTNCAYGTNAAYGGNGGNTCNGCNTGYYTNGARTTY TGYGCNCAYTGYTCNAARYTNGCNCARAARTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARGCNATGGAR YTNYTNAARTCNAAYMGNTCNGCNATHGAYGCNGTNACNGCNGCNGTNGTNMGNYTNGAR GAYGAYGARTGYACNAAYGCNGGNTAYGGNTCNAAYYTNAAYATHCARGGNAAYGTNGAR TGYGARGCNTCNGTNATGGAYGGNGCNTCNYTNTAYTTYGGNGGNGTNGGNGCNYTNTCN GGNGTNMGNAAYCCNGTNAARGTNGCNAAYATHYTNGTNAARGARCARGCNGARGGNCCN YTNCCNTAYGGNMGNGTNMGNCCNAGYGTNYTNGTNGGNAARGGNGCNMGNACNTTYTGY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARATHGGNGAYATHAARGARMGNTTYCARAAR AGYAARAARMGNYTNGCNMGNATHAARCARAARYTNGCNGAYGARAARAGYTGGGARTCN AAYATHGARMGNGCNATHAARGARGCNGARGARGARYTNGGNGTNAARYTNGAYMGNACN CCNGTNTCNGGNYTNTCNAGYACNYTNAAYAARYTNGTNAAYAARYTNCARGAYACNGAR GARGARYTNACNACNATGGAYAARGARATHAAYGGNYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TTYTCNTTYYTNGGNTCNYTNCCNATGACNATGMGNAARATGGARGCNGCNGTNCARGCN TTYACNCCNGGNYTNAGYTCNAARAAYYTNGTNGGNGTNATHYTNGGNGGNGTNYTNYTN GGNTGYGGNATGACNATHGCNGGNGCNTGYCCNGGNACNGTNYTNGTNCARYTNGGNGCN MGNGTNCCNAAYGCNTGGGCNACNGTNGCNGGNGGNYTNTGYGGNGCNYTNTTYTAYGCN ATGACNAAYTCNATHGTNACNAARGTNTTYAARGARGGNMGNAARCCNAARGCNTAYTTY YTNGAYMGNTAYYTNGGNATHCCNTAYYTNAAYYTNGCNTTYCCNYTNTCNTCNGTNYTN GCNYTNGCNGTNYTNGGNYTNGARCARTAYTCNCCNTGGCAYACNGARGTNTCNGARACN YTNYTNACNGARGGNYTNATGMGNGCNGGNGCNTGGCCNCCNTTYGTNGCNGGNATGATH ATHGGNACNYTNCARATHCCNATHGTNYTNGCNAAYGARGAYACNYTNGGNTCNGCNTCN AGYTAYGTNACNATHGCNTCNCARGTNGTN---------CCN---------TCNAARCAR GCNGGNTCNTAYYTNAAYAARTAYMGNAGYGGNATGAAYAAYTGGTGGCARGTNATHTAY GTNGGNGGNGCNGTNGTNGGNAGYTAYATHTCNGCNYTNGCNTCNGGNACNYTNGGNACN GTNGARGGNGTNCCNTGGTAYCARGCNTTYGGNGGNGGNYTNYTNYTNGTNTAYGGNTCN MGNYTNGCNGGNGGNTGYACNAGYGGNCAYGGNYTNTCNGGNATGGGNYTNYTNGCNYTN ATGTCNTTYGCNGTNGTNCCNGCNATGTTYGGNGGNGGNATHGCNACNGCNYTNTTYATG AARTAYATHYTNCARGTNGARATG------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGTTYMGNTCNGAYAARGAYYTNCCNTCNGGNATGYTNCCNTCN CARCCNTCNTCNCARATHTCNGGNTTYAAYGGNGGNACNAAYTTYTAYGGNCARGGNAAY YTNTCNYTNCARCAYMGNGCNATHGGNGCNAAYCAYTTYMGNGGNGGNAAYAAYACNGGN CAYATHACNCCNACNAGYATHAAYCCNGGNTTYCCNYTNGGNYTNCARCARCCNCARCCN CARCARCARCARCARCARCARCAYTCNCCNAAYAGYYTNGCNGCNATHGGNTCNMGNAAY GTNYTNGGNGTNCARAGYCARAGYGGNCARCARAAYATHGTNAAYATGCARAARMGNCCN TTYAGYTCNGCNGGNCCNATGCCNAAYTTYGCNTCNAGYTAYGGNTTYGGNGGNGCNGGN TCNATHGAYTCNCAYCCNACNATHGAYYTNTCNGAYTTYCCNACNYTNAGYAGYMGNTCN TCNGCNACNCCNAAYCCNYTNCCNTCNACNMGNAAYTAYGTNGGNATGGTNAGYAARCCN GCNCARGAYTCNGCNCCNGARTTYAAYATHTCNCARGARGARTTYCCNGCNYTNCCNGGN TCNCARAAYCCNCCNGTNCARTCNGGN---TCNGARTAYMGNCCNMGNGGNGGNMGNAGY AGYMGNGGNMGNGGNGGNCCNCCNMGN---GGNGGNTTYMGNGGNMGNGGNAGYTAYYTN GAYMGNGAYAGYGGNAGYAGYMGNGGNAGYTTY---------MGNGGNTTYTCNTCNMGN GGNMGNGGNGGNCCNCCNMGNAGYMGNGAYGAYYTNTCNCCNCCNMGN------ATHTCN MGNAGYTAYGARACNACNGAYMGNGGNMGNGGNCCNCCNCCNAGYMGNMGNCAYGAYMGN TAYGARGAYAGYTTYGAR---ACNMGNCCNTCNATHMGNATGAARGAYYTNTCNGCNTCN CCNCCNMGNGARTCNACNMGNACNTAYGAYMGNCAYTCNCCNCCN------CCNMGNMGN GARMGNGAYTAYYTNCCN---MGNCAYAGYGAYCAYCCNTCNTCNMGNGGNGAYTAYYTN CCNCCNMGNAGYTAYTCNCCNYTNMGNGAYTCNGGNTAYTCNACNTCNTAYAARGAYTCN TAYAGYTCNGGNCCNMGNGARGARMGNMGNCCNATGMGNGAYTAYCCNCCNMGN------ ------------TCNAGYGAYTAY---GAYMGNMGNGAYTTYMGNGARACNCCNMGN--- GAYTAY------AGYTCNAARGAYTAYCCNTCN---------MGNAAYGGNGARTTYMGN GAYTCNTTYAGYAGYMGNGARTTYMGNGAYCCNCCNMGNAGYGAYMGNTAYAGYGGN--- ---------------------------GGNGGNAGYGGNAGYAGYAGYMGN--------- ---------------GGNAGYMGNGGNAARTCNMGNTTYGAYGAYMGNGGNCCNGGNMGN GGNAGYMGNGAYGAYMGNGGNMGNGGNTTYATHAAYGGNTCNMGNGGNTCNMGN---GGN CCNCCNMGNGGNMGNGGNMGNGAYTTYGGNGGNAGYMGNGTN------GAYMGNMGNTCN CCN---------AGYCCNGARMGNGCNGGNGCNAARMGN--------------------- ---------------------CCNMGNYTNGAYTCNGGNGAYTAYMGNMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNACNAARYTNYTNYTNTCNCCNGAY ACNGCNGCNTCNTCNTCNAGYATHATGCARGTNACNGAYGAYCAYTTYATGAARGARCAY MGNAAYAARCAYAGYGGNCAYATGTAYTCNGAYCCNAARCCNTGY--------------- ---CAYTCNTCNGTNAARMGNMGNACNTCNYTNTCNAGYCCNGARAAYATGGCNGCNGCN CCNTAYTAYTAYACNGTNTCNCCNTCNTCNCARGGNACNGAYGARGAYATGATGTCNAAR ATGTCNACNGAYAAYCCNATH------ACNTGGCCNYTNTCNAGYATHYTNAAYATGGAY GARYTNCCNGARCCNGCNGTNGGNGCNTTYTCNGTNCARMGNCCNAAYGTNYTNAARGTN GARGARMGNGAYYTNCCNTTYGARGGNYTNATGAARMGNAGYATGATGGCNMGNYTNGAR CARAARCARAARCARGARTCNMGNGARAARGAR---------GAYAGYGGNTTYGARATH TCNAAYGARATGMGNAAR------GGNGGNACNAAYGARGAYGARAARGARAAYYTNGAY GTNYTNAAYACNTTYTCNAAYAAYGTNCCNYTNGARGARGARTAYGTNATHGTNGAYCCN CCNTTYGCNAGYGARGAYGAYCCNMGNGAYGTNAARTCNTTYYTNGGNGTNATGTTYMGN GCNCCNCAYYTNTAYGAYACNCCNGAYGTNMGNYTNAGYGTNGAYGAYTAYYTNAGYGAY GTNGGNGCNATGATGTCNMGNYTNGARGARGAYATGCCNGTNYTNGAYGARTTYTGYCAR TCNATHATHAAYTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CCNTCNCCNAAYGGNGCNATHCCNCCNCCNGCNCAYGTNCAYCCNMGN AARMGNTCNTAYCCNACNGAYCCNTCNCARGGNGTNTTYCCNAGYCCNGAYATGGTN--- ------------------------------------------------YTNYTNCCNYTN GCNACNTCNYTNYTNTCNATHAARCARATHGTNACNGTNTTYGTNTGGAARYTNATHTCN YTNYTNGAY------GARYTNGARAARAGYACNGARYTNTCNCARGARTGYTCNCAYTGY GTNAARAAYTTYTGGTCNYTNTGYTCNTGYCARCARAGYGCNGTNACNTCNTCNCARATG TTYGGNMGNTGGGAYGCNGTNYTNGTNGARTCNATHYTNCCNYTNGCNTCNATHATGATG GAYYTNTTYATHGTNGCNCAYCARGAYAARGARAARMGNYTNGTN------TGGTCNAAR AARYTNTAYAGYTGYYTNACNYTNGAYYTNCCNGAYMGNGCNGTNAARYTNTCNYTNYTN GARATHACNTGYGAYACNCAYGAYGGNGTNGAYATHGTNGTNCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYTTYACNCCNTTYTTYCARGGNCARAAYCCNACNAGYGTNCCNAAYATHACN TGYAARACNTTYAAYAAYGGNAGYAGYCCNAAYGCNGCNACNAGYCARTCNACNCCNAAR GCNAGYTCNTCNAAYTCNTCNTCNGGNAGYCCNGGNGARCARAARMGNCCNGTNAARGTN ATHAAYATHCCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGGARGGNYTNAARYTNGGNGARACNGARCARCARTAYTAYGCN GARYTNTTYCARGCNTGYGAYGTNGARGGNAGYGGNAARATHACNGGNCCNAARGCNTCN GAYYTNTTYMGNGCNTCNGGNYTNAAYTCNGARATGYTNMGNCARATHACNGARYTNTGY GGNGCNAARMGNYTNGGNCAYTTYGGNMGNAGYCARTTYTAYATHGCNYTNAARYTNGTN GCNATHGCNCARGCNGGNYTNCCNATHAARYTNGAYGCNYTNAAYCCNGGNAARGARATH TCNYTNCCNAARTTYGAYCARGCNGTNTCNGAYMGNAARAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARTTYACNGAYAAYGARATH MGNGARGARYTNGCNCARYTNGGNTAYCAYGAYGTNCCNAARGAYAARYTNGARGAYTTY AARAARGAYYTNATGMGNYTNATHTCNATHGARMGNAGYAARTCNAAYTCNYTNAAYAGY AGYCARACNACNGARCCNGARMGNGARGAYAARGGNTCNMGNCCNMGNCARTAYATHAAY ACNGGNTCNGTNGARGARGARAAYTTYACNAAYCAYGGNAAYCARTGGATH---GAYAGY CARTTYAAYGARGAYTGGCARTAYCARGGN------------------------------ ------------------AARAARGARAGYCARYTNMGNCCNCARACNGCNCCNGARCAR CAYGGNMGNCCNMGNMGNGGNATHYTNACNGGNGGNTAYTCNAGYTAYGARTCNTCNAAY GAYGTNGARMGN---------------AAYCARAGYTGYCAYMGNGARGAYGTNTCNGAR TCNGGNTCNGARAGYMGNATG---AARMGNAARACNTCNMGNAARACNGCNGGNGGNTGY MGNCARATHGAYGARTCNTTYACNGAYAGYGARTCNGGNGTNTTYGARATHTAYGARAAR ATHAARAARYTNGCNATGMGNGARTGYGARTGYGGNAARTCNAARTGYAARTCNGGNGAY GTNGARCCNCCNTAYMGNATHAARGGN---AARAAYAARAAYCCNTCNGTNATHAARAAR YTNGAYCCNCCNCAYAAYMGNAAYYTNGTNMGNATGGAYATGTAYCARMGNYTNAARATG TAYAARGARATHTGGAARGTNCARCCNCCNGTNAGYGARAAYGARMGNTCNTCNGTNMGN AAYGCNACNCAYGCNAARATGYTNMGNCAYGAYGARGTNAARYTNAARCCNAARGTNTTY GTNCCNAAYYTNTAYGTNCCNCCNCAYGARAARMGNMGNYTNGAYGTNMGNTGGAAYGTN MGNMGNGCNTTYGARGCNTAYGARYTNCCNGARCAYGGNCAYTAYCAYGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TAYAARTGYCCNTCNAGYYTNACNCAYMGNTTYTCNAAYYTNGTNATHYTNGAY AARCAYATH---AARACNGAYTAYCAYYTNCCNGARGCNAAYTCNTTYATHACNCCNYTN GTNGAYCCNCARATHMGNCCN------GARGARATHAARGAYCCNGTNCCNACN------ ---GTNCAYCARCCNYTNAARGARGCNAARGARATHYTNAARATHMGNCAYAARAARATG AARAARCAYAARYTNAARAARYTNMGNAARMGNATGTAYTTYGTNTGGMGNAARCARAAR ATGACNMGNAARGCNAARMGNGAYGCNGARTAYTGGAARGGNATHGGNGARATHAARAAR GAYGGNGARGAYTTYGARGCNGARGCNTTYGTNAARGARCARYTNGARAARGCNMGNMGN GGNGGNTAYTTYATHAAYGTNTTYAAYTCNAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARATHATGATH GTNYTNAARTCNGCNYTNYTNYTNTTYATHATGAGYYTNGCNYTNCAYTTYGTNGCNATH YTNTTYGGNGCNCCNGTNTCNACNTCNACNAARGARACNTTYCAYTTYGCNGCNYTNATG ACNGTNTTYATHGGNYTNCCNTGYTGYYTNGTNGCNGGNCCNAARTTYGAYAARTGGGTN GAYATHTTYACNTCNGAY---MGNGARCCNGGNYTNGARACNGTNGTNTAYYTNGCNAGY GTNGGNGCNYTNYTNGGNGCNTGGYTNGGNGCNATHCCNATHCCNYTNGAYTGGGAYMGN CCNTGGCARAARTGGCCNGTNAGYTGYTCNGTNGGNTGYATHTCNGGNTAYTCNYTNGGN YTNTTYGTNGCNTCNYTNTAYYTNCCNCAYCARTAYAARGCNYTNYTNAARCCNAAR--- ------------------------------------------GARGAYTTYATGMGNGAR YTNTAYGAYCARTCNGGNGGNMGNATHCCNGTNTGGGCNATHGGNCAYGCNGGNCAYACN MGNCCNCCNAAYMGNAAYYTNTCNYTNAARGAYATHGTNGAYACNGAYGARAARACNTAY GGNYTNCARGCNCARATHGAYCAYAARGTNACNTTYATHAARGARCAYATHCCNTCNGAY GTNCARYTNATHYTNATHGGNCAYTCNATHGGNTGYTAYTTYATHYTNAAYYTNYTNGAR AARATHTCNTCNCAYTGYGTNCAYMGNTGYTTYATGYTNTTYCCNACNYTNGARMGNATG GCNATHTCNCCNAAYGGNATHAAYYTNACNCCNATHTTYMGNCAYTTYMGNTGGATHATH ATHYTNYTNGCNTTYTTYTGYTTYYTNYTNCCNCARAAYGTNMGNMGNGCNYTNATHCAY TTYATHTAYMGNAARGTNGAYCAYCCNGARTGYATGATHCCNGCNATHATGACNACNGTN ACNCCNTGGACNGTNAAYTTYTCNACNTTYYTNGCNAARATGGARATGGARATHGTNACN GAYYTNCARAARGAYYTNGTNMGNAARCAYYTNGAYAARYTNAGYTTYTAYTAYGGNGCN AGYGAYYTNTGGTGYCCNATHCARTAYTAYAARGAYATGGTNGARGARTTYCCNYTNYTN GAYAARMGNYTNTGYGARYTNGAYYTNAARCAYGCNTTYGTNATGGTNMGNCCNCARGGN CARCARATGGCNGCNYTNATHTGGCARTGGYTNMGNACNCAYCAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GGNYTN GGNTAYYTNGAYCAYGTNYTNCAYCARAARTAYGGNYTNAARATHYTNGGNATGGARACN GTNCARAGYCAYGCNTCNGCNGCNGARAARMGNGCNGTNAARCARGGNATHACNTGYGAY GGNATHAARAGYYTNCARTGYCAYATHGARGAYAAYGAYGAYTCNTAYACNGCNTTYGTN TCNACNGTNAARACNGTNTAYCCNACNYTNCAYTGYGAYTGYGAYAARAARAARACNCAR CAYACNGARGCNGGNTAYTCNCCNAARATHTGYYTNATHGGNYTNCAYTGYTGYGGNGAY YTNTCNACNACNATGATGTCNTAYTTYTCNACNTGYGARTAYATHMGNGCNATHTGYTGY GTNTGYTGYTGYTAYCAYAARATGACNTAYTCNAAYGARAARTTYGCNAARTTYCCNYTN AGYGARGARGGNAARACNGTNTGYMGNCARTTYACNCARAARYTNGGNAARCCNTTYATH ACNCCNTTYACNYTNMGNYTNGGNGCNCARGARACNMGNTGYMGNTGGMGNCARCARACN AARACNGAYCAYGARTCNCAYATHAAYCAYGTNGCNTTYMGNGGNYTNYTNTCNTTYACN GAYGARGARGAYGGNCAYATHMGNCARAARGTNMGNCAYTCNAARTTYGAYTCNATHCAY GAYTTYATHGAYTCNTTYTAYGGNTCNTCNGTNGAYAAYCCNTCNACNGCNGARAARMGN TCNMGNYTNYTNTCNYTNTAYGAYCARTAYAARAARGAYTTYGAYGCNATHGARATHYTN ACNYTNYTNCARGTNATHYTNCARCCNGTNATHGARACNYTNATHTAYCARGAYMGNGAR CARTGGGTNAARGARCARGGNCAYGGNAAYGTNAARATHGTNACNGTNTTYGAYGARATG ATHTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GGNCAYTTYCARGAYATHCCNGCNMGNGCNTTYTAYAAYACNCARGTNGAYGTN ACNTAYTGGAARGAYTGGGAYAAYCARACNATGGAYGTNAGYATHGTNGAYMGNGAYTCN YTNACNGGNTCNGARGTNATHMGNTGGYTNTAYAARTTYCCNTAYCCNATGTAYCCNMGN GARTAYGTNTAYGTNMGNMGNTGYATGGTNGAYCARGGNAARAARTCNATGATHATHACN GCNMGNGCNACNAAYCAYCCNAARTGYCCNACNAAYAGYTCNAGYGTNMGNATHGARACN TAYACNTCNCARATGGTNATHACNCCNGAYACNGGNTTYGAYGARAARGGNTTYTCNTAY GTNATGTCNTAYTAYGAYGAYCCNCARACNAAYTTYCCNCCNATGTGYTAYAAYTGGATG GCNAGYGCNGGNGTNCAYGARTTYYTNGARMGNGTNCAYMGNGCNGCNYTNAAYAARCAY GARAAYAGYATH---GAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ACNTCNGCNYTNAGYGGNGCNGGNGTNATGMGNYTNTTYCAYAARGTNGGNGARTCNYTN GARAARATHACNYTNAARGTNGAYGARAGYGAYGARTGGTTYGARGARAARCAYCARCAR ATHGARGCNYTNGAYCARCARYTNMGNAARYTNCAYTCNAGYYTNGARGTNYTNGCNTCN CAYMGNMGNGARYTNTCNAGYAGYACNGCNGTNTTYGCNAARAGYGCNGCNATGYTNGGN AAYGTNGARGARCAYACNGCNYTNTCNMGNGCNYTNTCNCARYTNGCNGARACNGARGAR AARATHGARATHGTNCAYAARGAYCARGCNGARGTNGAYTTYTAYACNATGTCNGARYTN ATGAARGAYTAYGTNGGNYTNATGGGNGCNGTNAARGAYGTNTTYCAYGARMGNATHAAR TGYTAYAARCARTGGAARGAYGCNGARACNACNYTNGGNAARAARMGNGARAAYAARGCN AARATGGARGCNCARGGNAARGCNGAYAARATHTCNACNGCNMGNGCNGARATHACNGAR TGGGARCARAARGTNGARAARGGNCARGARGAYTTYGARAARATHTCNAARAAYATHMGN AARGARGTNYTNMGNTTYGARAARYTNMGNGTNTCNGAYTTYAARACNAAYGTNATHAAR TAYYTNGARGTNYTNATGGAYAAYCARGARAARYTNATHAARTAYTGGGARACNTTYYTN CCNGARGCNAARGCNATHGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARTGYCCNCAYGARGGNTGYAAYAARAGYTTYYTNTTYCCNGCNATHYTNAARMGNCAY ATGAARGTNCAYCARGGNTAYCCNTGYGAYGTNGAYGGNTGYTGYGARGTNYTNTCNACN TGGACNAARYTNMGNAARCAYAARGCNGTNGAYCAYGTNCCNAGYYTNGTNTGYGARATH TGYGARAAYGTNTTYAARACNMGNCARATHYTNGTNCARCAYATGAARATHCAYACNTCN ATHCARGARCCNGTNATGTGYCCNAARGAYGGNTGYCAYMGNACNTTYYTNTAYAARAAR AAYYTNACNCARCAYATHMGNGCNTTYCAYGARGGNAARYTNGTNTTY---ATHAARAAR MGNAARGARMGNGARMGNGTNCARAARAAYCARMGN---GTNCCNAARMGNAAYAGYGCN GCNGCNMGNYTNTGYGGNYTNCARGAYMGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARCCNGTNATHATHACNGGNGTN GTNTCNGGNYTNACNCCNGTNCCNTTYGAYTAYTCNYTNGTNATHGARCAYGCNGGNAGY ATHAAYATHACNACNAARGARGCNYTNAGYAAYTCNGTNACNTGGGCNAARYTNGARAAY AARMGNGARACNACNGTNTCNGARYTNATHCAYGGNGTNMGNACNGGNTCNGTNAAYGAY TTYYTNTTYGAYTGGAGYYTNCCNYTNCAYTGYCCNAGYYTNGCNGGNCARATHTCNYTN CCNTCNTAYTTYAARGAYAAYGTNYTNYTNCARACNGCNCCNGGNTCNYTNTAYMGNGAY AGYTGGCCNAGYYTNTTYATHTCNCCNAARGCNGCNACNACNCAYYTNCAYGTNGAYGCN TTYCAYTCNCAYTTYTGGATGGCNYTNTTYCARGGNGARAARMGNTGGACNTTYTTYGAY CARMGNGAYACNGCNYTNYTNTAYCCNMGNYTNTTYCARTCNYTNGAYCCNGTNTTYGAR GTNGAYYTNAGYGAYCCNGAYYTNGARAARTTYCCNYTNYTNGCNYTNACNMGNCCNCAR CARTGYGTNYTNGGNCCNGGNGARYTNYTNTTYGTNCCNGCNGGNAGYCCNCAYTAYGTN GARAAYYTNACNCCNACNYTNGCNATHTCNTCNAAYTAYGTNGAYCAYACNAAYTTYCAY AARGTNTGYGARGARYTNMGNATHAAYGCNYTNCARGAYCARMGNGCNAARGAYYTNYTN GTNCARYTNCARGAYCCNGCNTTYYTNAGYMGNATHCARTCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TCNGGNCCNCCN GARCCNGCNCCNMGNCARCARCARCARTTYGARGAYGAYGAYGAYGARGARGARGARGGN GTNTAYGARAAYGARCCNGTNAARMGNGAYGAYGTNGCNMGNGARTCNGAYAARAARGAY GAYGTNAAYYTNCCNTCNCCNGGNYTNGCNCARAAYYTNYTNGCNAARTTYACNTCNGGN CARGCNGARGGNCCNACNCCNMGNGCNAARMGNGARATHACNCCNCCNAAYCCNACNATG GGNGGNGGNGARTAYGTNTCNGARCCNMGNGTNGTNTTYGARAARTAYGARGGNAARGCN GARTCNGGNGTNTTYGARAGYGARCCNCARCAYGAYCCNGCNATHGTNMGNTCNGAYTCN TAYCARGARGARTCNYTNCCNGARCARGGNTAYGCNAARAARTTYGCNGCNMGNTAYACN CARATHGAYAARGARMGNAARAGYACNGTNATGACNAGYAAYMGNGAYATHGCNGCNGAR MGNGGNACNGAYCARGTNGARTAYGTNTCNGARCCNMGNGGNCARGTNGARMGNTAYGAR GGNAARGCNGARTCNGGNGTNTTYGARAGYGARCCNGARCAYATGCCNGAYGTNGTNMGN GCNGTNGAYAAYGTNAARGARGARGTNGTNCCNGARMGNGGNACNGCNMGNAAYYTNGCN GARMGNTTYCAYCARATHTCNATHGAYGCNGCNTCNCCNCARGCNAGYMGNAAYAARMGN GARATHACNCCNGAYTCNTCNGCNMGNACNGARTTYGTNAGYGARCCNMGNGGNCAYGTN GARCARTAYGARGCNAARACNGARTCNGGNGTNTTYGARAAYACNCCNCARGARGAYCCN GAYGTNGTNAARGCNGGNAAYGCNGCNGARGARTAYATHCCNGARMGNGGNTAYGCNMGN AAYGTNGCNGCNAARTTYAARGARYTNGARAAYACNGCNAARTCNCCNCCNYTNTCNCCN GGNMGNMGNAARGARATHACNCCNCCNMGNGARGAYATHAAYAAYGGNACNTCNGGNGTN TAYGARAGYTCNCCNGARATHAARCCNGAYGTNGTNACNTCNGCNGARGCNCARCARGAR GTNYTNCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGAAYMGNGGNYTNAARACNCARYTNATHMGNGCNTCNATHAGYCARAAY GTNMGNGARGGNGCNTTYTGYAARTAYAGYCAYMGNGAYTGYACNCARAAYTGYYTNGAR GGNTAYGCNTAYTGYATHMGNCAYATHYTNGARGAYAARCARGCNCCNTAYMGNCARTGY GCNTAYATHACNAARGCNGGNMGNAARTGYCCNTCNGCNGCNCCNAARYTNGARAARAAR GARGGNTAYTGYGCNTTYCAYACNAARAARGCNYTNATGACNMGNCARMGNATGGCNMGN AARMGNMGNCCNMGNGARACNCCNGAYAGYYTNYTNGARGAYYTNGTNGTNACNACNTCN TCNATGGAYTCNCARCAYAGYATHGARCAYMGNMGNGGNAARATGCAYAGYGAYAGYATH GCNACNMGNGCNYTNGARTAYGCNAGYTCNAGYGAYTCNGARACNGARYTNYTNYTNGTN GARCAYGCNTGGMGNGAYTCNGGNGAYAGYGAYGCNGARAGYATHGAYAGYGAYCARGAR GAYGTNYTNAARTAYGCNGGNGTNTAYACNACNGARGARGTNGCNCARATHYTNMGNGAY AARYTNATHMGNYTNCARGCNYTNTAYATHGAYCARTTYAARMGNYTNAARCAYGTNYTN YTNMGNAARMGNMGNAARTAYYTNCARACNCARAARATGGARAARGARYTNTAYGGNAGY ATHAARMGNTAYAARGAYGAYCCNCARCARMGNGARAARTAYGARAARYTNTGYGCNATG AARMGNTAYCAYAARAARTTYGGNGTNGARGCNYTNATGCARMGNAARTCNACNCAYMGN MGNATHAARGTNACNGARGGNATGAGYCAYAARYTNCCNACNCCNGTNAARTGYACNTTY GTNGAYGARGGNYTNMGNTGYTGYCARGCNGTNGTNCCNYTNAGYAARTTYTGYCARAAR CAYATHYTNCAYGAYCARAAYCARGTNYTNTAYMGNCCNTGYCCNTTYGCNGAYAGYCAR TGYGGNMGNCCNGTNCCNACNYTNYTNGGNAGYCARTTYTGYTCNYTNCAYCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNGAYGARGAYTTYACNMGNGCNCARGARATGATHATGACNYTNGAYAARGAY ATHTCNGARYTNAARATHAGYAAYMGNGAYYTNCARAARGAYATGGAYTCNTGYMGNGAR MGNGARTCNAARATGYTNGCNYTNCARTCNGARYTNAGYMGNACNAAYGCNTGYYTNMGN TCNGARAAYACNACNYTNAGYAAYAARGTNACNAAYCARACNGCNGAYGTNGARMGNYTN AARATGGARATHCARGARATGGARACNACNGTNAARCAYYTNACNGAYTCNATHGARGAY GARAARAARAAYAAYACNCARACNYTNACNAARYTNAARGGNTCNYTNGARGARAARACN AARGARAAYTCNGAYTTYAARCARAARTGGGARGAYGARATHGAYAAYAAYAARACNYTN AARMGNMGNCAYGCNAAYAAYATHAARGAYYTNACNMGNCARYTNCAYCARACNAARMGN MGNYTNGARACNYTNGARGGNAGYMGNAARGAYAGYGGNGAYAGYATGGGNTCNMGNACN AAYTCNAAYGGNAGYYTNAAYTCNGTNGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARGCNAAR ACNGGNGGNGCNGGNAAYTAYCARACNTTYATHYTNCAYGAYGARGAYCAYACNYTNGGN AAYTCNATGAARTAYATHYTNAAYAARAAYCCNGAYGCNACNTTYGTNGGNTAYAGYATH ACNCAYCCNTCNGARAGYAARATHAAYYTNMGNATHCARACNTCNGGNAAYTCNTCNYTN CARGTNYTNAARGARGGNTTYAARGAYYTNMGNCARYTNTAYGAYCAYATGYTNACNACN TTYGARTCNTCNACNAARTAYTAYAARGARAAYCAYATGGAYGTN---AGYGAYGGNACN CARTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARCAYGAYMGNMGNTCNAARCAYCARTCNAARGTNGAYTTYTCNAAY TCNGTNGCNGAYGAYYTN------------------TCNTTYGARCCNTGYGARGAYGAR YTNGCNGCNACNGCNTTYCCNYTNGCNATGTGGGAYYTNGARCAYTGYGAYCCNAARAAR TGYTCNGGNAARAARYTNAGYMGNYTNGGNTTYGTNAARACNYTNMGNYTNAAYCAYMGN TTYGGNGGNYTNATHYTNTCNCCNGTNGGNACNAARTGYATHTCNCCNGAYGAYMGNACN YTNGTNGARGARAAYGGNGTNGCNGTNATHGAYTGYAGYTGGGCNAARYTNCARGARACN CCNTTYGCNMGNATGAARGGNGAYCARCCNMGNYTNYTNCCNTAYYTNATHGCNGCNAAY CCNATHAAYTAYGGNMGNCCNTGYAARYTNTCNTGYGTNGARGCNTTYGCNGCNACNYTN TTYATHACNGGNTTYTCNAARGARGCNGARYTNYTNYTNGGNAARTTYAARTGGGGNTCN TCNTTYATHTCNYTNAAYAARGARYTNYTNGAYGCNTAYAGYGGNTGYCARACNAGYCAR GAYGTNGTNTCNGARCARGARACNATHYTNGCNMGNTTYCARGARGAYAGYMGNCARGAY AARYTNACNGAYTGGTTYTCNGTNGAYYTNGAYGTNGAYGTNTGYAAYCCNAAYMGNCCN YTNTAYTCNTCNAGYTCNGCNGARGAYACNGAYGARGAYTCNGARGARGAYGARGAYGAY AGYGAYAAYGARAGYGARCCNGTNGARAAYGARTCNGAYGGN------------------ ------------ATGCARTGYGCNGCN------AARAGYCCNGARYTNTTYYTNGARATG GCNATGAAYATGCARAARGAYAAYGAYGAYAARGTNTTYAAYATHTTYTGYAAYCAYAAR CCNGCNGTNGTNGAYATHGCNYTNTGYATGATGGAYAARATGGARGAYTGYTTYCCNGAR GCNAARCCNGTNATG------AARYTNATHGGNTCNAARGAYMGNTGGYTNAGYGCNATG AARYTNATHTGYGAYAAYAARGARACNYTNATGGAYACNTGYATGGAYGAYAAYATHGGN ---TCNTTYATGACNTGYTAYATGGGNAARGTNACNACNYTNGCNAAR------------ TCNGGNYTNAAYGGNAARCCNAARGARATHGTNTGYMGNGTNATHCAYTCNGARGARAAY TGYYTNGTNGARAAYAARGGNTCNTGYAGYGAYAARTAYGTNCARGTNYTNAARGAYTTY YTNGARACNATHTTYCCNGTNGARCAYTGYCCNGCNGTNATHAARAAYCAYGGNGAYYTN GCNAAYTCNYTNGGNAGYATHYTNGTNCAYGGNCARCCNGGNYTNAARTTYAARCCNTAY GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CARGARGAYYTNACNGARYTNAARAAY CARGTNYTNGGNATGGAYGAYMGNCAYGARAARGARAARGAYCARTGGYTNCARGARAAR AAYAARGTNATHMGNTAYCARAARCARYTNCARYTNAAYTAYGTNCARATGCARMGNAAR AAYTCNACNYTNGARACNGARGTNCARCARYTNACNYTNGARYTNGARAAYMGNGAYATG AARYTNATHGCNYTNAGYGGNGARGARAGYGTNTGYTCNTTYTTYYTNCCNTTYTTYCCN YTNGCNGTNATHYTNAAYYTNGGNTCNYTNATHTAYATGYTNCARTGGCARCCNGTNCCN GGNTCNYTNGTNCCNTAYTTYGTNATHATGGGNATHTGGGGNATHAGYGAYGGNTTYTGG AAYACNCARGTNAAYAGYYTNGTNGGNGTNATHTTYTCNGAYAARTTYGARGARGCNTAY GCNGGNYTNMGNATGYTNCARGGNYTNAGYGTNGCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNCCNACNTCNGCNATG ACNCCNCCNMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNACNAAYGARTGYGARAGY GTNCCNATHGGNGARACNATHGAYGAYGTNCCNATHMGNGTNACNTCNMGNGARGTNAAR AARATHGAYTTYCAYAAYAARYTNTAYYTNGCNCCNYTNACNACNGTNGGNAAYYTNCCN TTYMGNMGNGTNTGYAARAAYTAYGGNGCNGARATHACNTGYGGNGARATGGCNYTNGCN ACNCARYTNYTNAARGCNAARGCNTCNGARTGGTCNYTNATHAARMGNCAYCCNTGYGAR GAYATHTTYGGNGTNCARGTNTGYGGNGCNTAYCCNGAYATGATGACNAARTGYGCNCAR GTNYTNACNGARACNACNGAYATHGAYTTYATHGAYATHAAYTGYGGNTGYCCNATHGAY YTNGTNTTYAARAARGGNAGYGGNAGYGCNYTNATGGGNAARGCNTCNAARYTNGARCAR ATHTGYMGNAGYATGATHGGNGTNATGGGNGARACNCCNYTNACNGTNAARYTNMGNACN GGNGTNTTYGAYAAYAARAAYGTNGCNCAYAAYATHATHCCNMGNYTNMGNGAYGCNGGN GTNTCNYTNGTNACNATHCAYGGNMGNTCNMGNGARCARMGNTAYACNAARYTNGCNGAY TGGCARTAYATHGAYGARTGYGCNAARYTNGGNCARCCNATGCCNGTNTAYGGNAAYGGN GAYATHYTNTCNTTYGARGAYGCNAAYYTNCAYATGGARMGNAAYGGNGTNTCNGGNGTN ATGYTNGCNMGNGGNGCNYTNATHAARCCNTGGATHTTYACNGARATHAARGARCARMGN CAYTGGGAYATHTCNTCNTCNGARMGNYTNGAYATHYTNMGNTCNTAYGCNAAYTAYGGN YTNGARCAYTGGGGNTCNGAYCAYCARGGNGTNGARTCNACNMGNMGNTTYYTNYTNGAR TGGYTNTCNTTYYTNCAYMGNTAYATHCCNGTNGGNGTNYTNGARCARGTNCCNCARAAR ATHAAYGARMGNCCNCCNTAYTAYATHGGNMGNGAYGAYYTNGARACNYTNATGGCNAGY GCNAAYTGYGCNGAYTGGGTNAARATHAGYGARATGYTNYTNGGNCCNGTNCCNCCNACN TTYCARTTYYTNCCNAARCAYAARGCNAAYGCNTAYCAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------GARAARYTNGTNGAYGCNGARGTNGTNATHAARGTNGAYTAYAARGGNAGYACN AGYTAYMGNAAYGCNTCNAARTGGMGNAARAGYATGATHGGNTGYGCNGTNCARAAYTCN ACNACNGTNTCNACNAARATHATHGARGCNATHYTNGTNYTNTCNAARACN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CARYTNYTNACNTCNTCNTCNCAYGTNCARYTNGCN AGYCARGARTCNCAYMGNCAYATHGARAGYYTNCARGARCARYTNCAYCAYYTNGCNAGY CARMGNGAYTCNGCNTAYATGCARGTNGCNACNACNCARGAYCARTGYGARCARTAYGCN GCNTCNYTNAGYAAYYTNCARYTNGTNYTNGARCAYTTYCARAARGARAARGAYTCNGCN ATHGCNATGGARACNGARMGNTAYCARGAYCARGCNAARTCNYTNTCNTCNAARGTNAAR GARYTNCARGCNGARYTNGARMGNACNMGNACNGAYYTNACNGARGCNYTNGAYGGNYTN GAYGCNGCNTCNMGNYTNAGYGARCARYTNGAYMGNAARGARGARGCNYTNATGGCNYTN AARGARGARGTNCARATGMGNGARGAYGCNYTNAARATGGCNGARGAYGARATHTCNAAR YTNAAYTCNAGYACNGARGCNAARGTNGAYAARACNYTNATGCAYAAYATGGTNYTNACN TGGYTNACNTCNCCNGARAARAARMGNCAYGARATHGTNCARYTNATHGGNCAYGTNYTN GAYTTYAGYCAYGAYGAYTTYTCNAARATHGARTCNGCNCAYGGNCARGAYAGYYTNTGG ATHGGNTTYTTYAARCAR---AARGCNGAYTCNGAYACNAAYAARCCNAGYAARGGNAGY CARTCNTTYTCNCARYTNTTYGTNAARTTYYTNGARAARGARTCNTCNCCNCCNCCNACN CCNGTNAARYTNCCNGTNGARGCNATGGCNGCNGARGCNCARYTNMGNCAYAARACNGCN TTYAAYCCNTTYACNGCNCCNMGNCAYGTNACNCAYGGNAAYGARAGYYTNGGNATGTCN TCNGGNTCNTCNTCNCAYYTNYTNATGCCNCARGAYACNCCNCAYCCNTCNCCNYTNTTY GCNCCNGTNACNACNGTNTCNAAYGCNGGNGARAGYGCNATHYTNAARGAYGTNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGYTNTTYAAYYTNGARGAYTGGAARCARGGNATGGAYYTNYTNTGYGARGAYYTNAAY MGNAARYTNGTNTTYAGYGAYCAYTTYGGNTGYYTNTCNCARTTYACNCCNMGNATHGCN AGYTGYATHYTNATHMGNACNCARATGTTYAARAARGCNGTNATGGAYGCNGGNATGGCN ACNCAYAARACNYTNCAYGAYATHACNTGYAAYTAYGCNGARAAYATHGTNAAYTGYYTN GARAGYCCNYTNGCNAARTCNTGYCCNATHYTNGTNGTNGAYACNATGGTNACNGCNYTN CAYMGNTTYYTNCCNCCNGCNTGYGCNCCNGTNCCNGCNATH---------AAYCCNMGN AARGGNGARGCNAARAAYTCNCAYGAYGCN---GTNYTNGARACNGTNATHYTNGARGGN GGNGGNGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CAYAAYATGATHGARMGNMGNMGNMGNTTYAAYATHAAYGAYMGNATH AARGARYTNGGNGGNYTNYTNCCNAARACNGTNGAYCCNGAYTCNMGNCARAAYAARGGN TCNATHYTNAARGCNTCNGTNGAYTAYATHAARGCNYTNCARGAYGAYCARMGNMGNTTY MGNGGNATGATHGAYGARAARAARAARGCNGARYTNGAYYTNMGNAARGTNYTNATHMGN GTNAAYCARATGAAYYTNGTNATGAARTCNCAYGGNATHGAYTCNTGYGGNYTNGGNGAR YTNGARYTNAGYTCNAGYGTNGCNAGYAAYCCNTCNAAYTTYYTNACNTCNCCNYTNACN ATGACNCCNATGAGYGTNGTNCARAAYACNATHGTNAAYAGYCAYGCNTTYYTNAGYAGY GCNATGTCNCCNGTNGAYGAYYTNATGGAYGARTCNTCNCCNGTNAGYGGNGAYCCNATG YTNATGTCNGCNCCNGTNAGYCCNGARCARGAYGARGTNGGNTTYCAYTTY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGYATGCAR GTNCCNMGNCARYTNGGNGARATHGCNTCNTTYGGNGGNAGYAAYATHGARCCNAGYGTN MGNAGYTGYTTYGARAARGCNAAYGGNMGNCCNGARATHGARGCNTAYCAYTTYYTNGAY TGGYTNAARYTNGARCCNCARTCNYTNGTNTGGYTNCCNGTNYTNCAYMGNYTNGCNGCN GCNGARACNGCNAARCAYCARGCNAARTGYAAYGTNTGYAARGAYTTYCCNATHGTNGGN TTYMGNTAYMGNTGYYTNAARTGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GCNGGNYTNAARYTNGCNTAYATHGAR GGNTGGAARYTNATHAAYYTNGCNAAYGARACNTTYGGNTTYACNGGNTGGTCNCAYTCN GTNAGYAAYCARGTNGTNGAYTTYGTNGAYCAYGTNAAYGGNAARTAYTAYGTNGGNGTN AGYGCNTCNGTNMGNGTNACNYTNAARAGYGGNGCNTAYCAYGARGAYGTNGGNTAYGGN GTNAGYGARGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGTCNGCN CCN---ACNGARAAYAAYTTYYTNCCNTGYGAYGAYTTYATGAARTTYCARGAYGCNYTN AARAARYTNMGNYTNATGGAYGAYMGNATHATHCAYGCNYTNAAYMGNAAYATHCCNACN CARTCNTTYCARGAYAARGGNAAYGTNAAYACNAAYTGYAARCAYGTNTAYGAYGAYATH CARACNTCNTAYGAYCAYMGNGARAARTCNATHCAYCAYTGYATHMGNYTNGTNAGYGAY GAYGTNAARAARYTNAAYGARAARMGNCARCARGAYCCNGAYAAYYTNAAYGTNATHAAR TCNYTNMGNATGGARCARACNAARYTNMGNYTNATGCARCARGARYTNAGYATHGARGAR GTNGTNAARGAYMGNACNYTNAARGTN--------------------------------- ---------------GTNTGYCAYYTNGCNGGNYTNGTNMGNGGNCAYGGNCCNCAYTCN CAYATGTTYGAYGGNAARTTYATHCCNYTNGTNMGNGGNAAYATGGAYTGGAARCAYGAR AARGCNACNYTNAARATGTTYGAYTTYYTNGTNGAYGAYAAYGGNYTN------AARGAY GGNATHTTYGAYAARTAYGGNYTNGGNCCNYTNGAYATHAARTTYATHAARGARYTNATH TAYGGNCCNYTNAAYGAYAAYGGNCARYTNTGGCCNTAYGARGGNMGNGARGARAARAAR TCNTTYYTNTAYGARATHGTNTCNAAYAARCCNACNGGNATHGAYGTNGAYAARTGGGAY TAYTTYGCNMGNGAYTGYCAYCAYYTNGGNATHGTNAAYAAYTTYGAYCAYAARMGNTTY ATHAARTTYGCNMGNGTNYTNAARGTNGAYGGNMGNTTYMGNATHTGYGCNMGNGAYAAR GARATHGGNAAYYTNTAYCARATGTTYTAYACNMGNTAYAAYYTNCAYMGNACNGCNTAY CARCAYAARGTNTCNTTYGCNTGYGARATHATGGCNGTNGAYGCNYTNGTNAARGCNAAY AAYCAYATGYTNTTYCCNGGNAARAAYGTNGARYTNAARATHTCNGARTGYATHGAYGAY ATGACNGCNTAYATHCARYTNACNGAYGAYATHATHTGGCARATHTAYATHTCNCARGAY CCNAARYTNGARGARGCNAARAARATHGTNAARMGNATHTAYTCNMGNGAYYTNTAYMGN TGYYTNGAYGARAGYAARMGNYTNCARGARCARGGNGGNAAYATGGTNATGGCNACNATG AARAARYTNGAYGARMGNYTNATHAAYATHTCNGARACNGTNGCNGARCCNGGNACNGAY TTYMGNYTNYTNATHGTNTAYATGGAYTTYGGNAARAARGAYAARGAYCCNYTNAARGCN ATGMGNTAYTAYTCNAARTCNGARCCNAAYAARCCNATHGARGGNCAYGCNGCNGGNYTN YTN---CCNCCNMGNTTYAAYGAYAAYYTNATHMGNGTNTAYAGY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GGNATGAARAARTTYGARATHCCNGAYCAYYTNGAYYTNGGNAAY CARCAYTCNTTYGARATHAARGAYYTNGARAAYYTNATHAARAARACNACNTCNGAYYTN GARAARYTNGAYCARCARMGNAARGARGARTTYAARGARTAYGARATGGARAARAARTTY GARCARGARGAYCAYYTNAARCARATGAARGARGAYGARMGNAARAARGARGARGARMGN YTNTCNGARYTNAARAARAARCAYAARGARCAYCCNAARATHCAYCAYCCNGCNAGYAAR GAYCARTTYGARGARGTNTGGGARAARGAYGAYCAYYTN---GAYCARGARTTYGAYCCN MGNACNTTYTTYTTYACNCAYGAYYTNAAYGGNGAYATGGARTGGAGYATHGAYGARGTN GAYGCNGTNYTNCARMGNGARYTNGAYAARGTNTAYGAYGARMGNAAYTCNCCNGAYGAR GAYGAYCCNATGGARMGNGARGARGARATGAAYMGNATGMGNGARCAYGTNTTYACNGAR ATGGAYAARGAYAAYAAYAARMGNATHTCNTAYGAYGARTTYATHYTNTAYACNGGNGCN CAYGGNGARAAYCCNGARTTYAARAARGAYGARGGNTGGAARACNYTNGAYGARGARCCN GTNTTYGAYGAYGAYGARTAYGARMGNTTYATHMGNGARCAYCAYGCNCARCCNGGNGAR GTNAAYCCNCCN---GCNGAYYTNCAYTTYAAYCCNGAR---------CAYCARGGNCAR TTYGAYCARCARCAYCAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGACNAAYGCNCARTGYAGYGTNGAYTCNYTNTTYGAYGGNATGGAY TTYTCNTAYAAYATGTCNMGNGCNMGNTTYGARAGYYTNGTNGTNCCNYTNATGTCNCAY TGYACNCARYTNGCNCARCARGTNYTNGAYAARGCNGGNTGYACNAARCARGAYATHTCN AARGTNATHYTNTGYGGNGGNGGNGCNAARTCNCCNATHGTNAARAARGTNATGACNGAR TTYTTYCCNTCNTCNTCNYTNYTNAAYTCNATHCCNGARGAYGARATHATHGCNATHGGN GCNGCNAARGARGCNGCNYTNYTNGARGGNGAYGARGARGARAARGTNAARATGGGNGAR GARAAYACNATHACNTTYAARTCNYTNTCNAARGCNGTNTGYYTNMGNGTNAAYTCNCCN GARGTNCARGTNATHYTNCCNCARCAYTGYYTNATHCCNGCNMGNMGNCARCAYACNYTN ACNYTNCCNCARTCNCARACNAGYGTNGCNYTNGARATHYTNCARGCNGAYGARCCNATH ACNTCNGAYGAR---GCNCARYTNYTNGCNAARGTNGTNYTNAARGAYYTNCCNCCNGGN TCNACNATHAARTCNAGYTTYCAYYTNACNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARACNYTNAARGAYATHAARGAYAAYYTNGAR AARAARYTNGCNGGNCARCAYAARYTNAGYAARGGNGARGARYTNATHTAYGAYGCNYTN AARGAYGTNAGYYTNCCNGCNYTNTTYATGCCNTAYAARACNGGNAAYATHTTYAAYCCN MGNGCNCAYYTNTAYTTYCAYCCNACNGGNTCNTCNGAYGTNMGNYTNACNCARCCNCCN TCNATGTTYACNYTNCCNCCNYTNCCNAAYAGYAARYTNTCNGTNGTNAAYYTNTTYGAR YTNAGYAARAAYTTYCAYAAYTGGGGNCCNGCNTGGYTNGTNGARMGNTAYATHCARCAR CARCARCCNTCNCAYGARGAYTGYCCNCARACNCCNGCNCCNACNTCNGCNGTNCCNCAR GTNACNACNACNTCNGGNCARAGYCCNATHAAYGARMGNATGACNTCNCCNACNAGYYTN MGNAGYATHCARCCNGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CCNMGNMGNMGNCARCCN--- CARGCNGCNCARMGNYTNCCNTTYCARGGNGGNGTNCCNTAYGGNGCNTAYCCNGCN--- CCNGGNGGNCARTTYGTNCCNGTNATGGCNGGNCCNCCNCCNCARTTYCARCCNGTNCAY ATGGTNCCNCCNAAYTAYCCNCCNCCNCAYTAYCCNGTNGARGCNTCNCAYCCNCCNACN TCNCAYTCNAAYGTNCARCCNACNGAYCCNCCNGTNTAYTCNTAYYTNGTNMGNMGNGGN TAYACNCCNYTNGAYCCNCAYAAYGGNAGYGCNGGNAGYGCNAAYTCNAGYCARMGNAAY GGNCCNACNCARMGNGARGARCCNGAYACNCCNYTNCARAGYGGNATHGAYTAYATGMGN MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TGYAGYGARTGYATHCCNAARGTNCAYTCNCARCAYGARAGYGARATHGGNCAR YTNACNGAYGCNGTNTTYAARAAYAARGARACNYTNYTNAARTTYGGNGAYGARTGYGGN AARAARYTNGARGGNTGYCARAARATGAAYTCNAAYYTNAAYYTNGCNTTYGARGARYTN GARATGCARAARGAYAAYACNAARGGNYTNATHGARGARACNTTYCARAGYTAYAARGTN ATHYTNGARGARGCNMGNGAYGCNTGYYTNAARGARYTNGAYGAYYTNCAYGARAARMGN GARATHGGNYTNATGGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CCNAARMGNTGGGARGCNTAYTCNAAR ATGGGNAARGTNATHYTNGGNACNACNATHATGCCNATHAARGCNCCNYTNMGNGARAGY ATHACNAGYTCNYTNCCNCCNGARGARMGNTTYTCNCCNTCNTCNYTNYTNYTNYTNYTN CARAARGAYAAYYTNAARYTNGGNGGNGTNGTNGAYYTNACNTAYACNACNMGNTAYTAY GAYAGYCARTTYTTYACNGARAGYGGNATHGGNTAYMGNAARATHTTYACNGCNGGNMGN GTNATHCCNGAYAAYAARACNTAYTAYCARTTYGCNAGYGCNATHAARGARYTNGARAAR GARGGNGARGTNACNTGYGTNCAYTGYACNCAYGGNYTNAAYMGNTCNGGNTAYYTNATH TGYMGNTAYATGATHGARTTYYTNAAYATGGARCCNCARAARGCNATHAARYTNTTYGAR GAYGCNMGNGGNTAYAARATGGARMGNCCNAAYTAYATHGAYGAYYTNATGACNMGNAAR CCN------------------GGNGAYTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TCNATGTTYATHGAYGAYACNAARCARTTYTAYGGNGTNACNACN MGNYTNTGGGGNGGNGARAGYYTNAGYTGYTTYACNMGNMGNGARYTNGARYTNTAYMGN CARTTYTCNTCNGAYYTNCCNGTNATGGGNGTNGTNYTNATHYTNGCNTTYGCNCCNGGN GGNGTNYTNATHTTYCCNYTNGCNTAYATGTTYCCNMGNCAYYTNYTNTCNTCNCAYTTY TGGACNAARCARCARAARGARGARTTYGGNCARYTNGARYTNAARAARMGNYTNAARCAY TAYCCNAGYATHYTNGAYAAYATGTAY---GAYMGNTGYAGYMGNAARCARYTNGTNAAR AARGTNGTNAAYAARYTNGAYACNTCNTGGCAYYTNAGYAARTCNYTNGGNTTYTCNATH MGNGARMGNAARYTNGTNAARGARGCNYTNYTNYTNCAYTTYATHGAYAAYGCNYTNCAR MGNGARGGNATHCAYAAYYTNACNGAYGAYGAYYTNGAYAARGCNTGYACNTGGMGNGGN YTNAAYCCNMGNGGNATGAAYMGNGAYGCNAARYTNTCNCAYYTNAARAGYTGGACNGAY ATHACNACNCAYGTNCAYGARTCNAGYGTNTCNYTNYTNYTNCAYYTNCCNGTNYTNYTN AGYTAYTGYCARCCNTCNAAYMGNAARYTNATGGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGYTNGARGARGARAGYGTNACNATGGAR AARAARNNNCCNGCNMGN------CARTCNCCNAGYCARTGYMGNAAY---GGNGTNTCN GGNGARMGNAARTCNGAYTTYACNCARAAYMGNTAYGGNMGNGTNMGN------MGNCCN GTNTCNAAYGGNGGNACNAARACNCCNGAYGTNCARACNCCNMGNCCNATHCCNATGCAR AARTGGGAYAARTCNATGGGNGAYMGNMGNCARMGNCARMGNGGNTAYTAYGAYTAYMGN CARMGNGARGARGTNGTNGAR---AGYGAYACNTAYGAYGTNYTNAGYACNGGNTCNMGN AARGGNAAYGCNAAYCAYYTNYTNAAYTTYAARTTYTAYCCNMGN---CARAGYCARYTN GGNGARCAYMGNTGGTAYGAYAARAGYCAYTCNAGYGCNCAYGGNMGNGGNGGNTAYMGN AARACNACNMGNTAYAARAARGARCARTTYYTNCARGCNAGYTGYCARTTYGTNGTNMGN GAYACNGARGARTAYACNGARCARGCNATHAAYCCNGAYGTNYTNGTNGAYTGGAAYATG ATHGARYTNGTNMGNAGYTTYTCNACNGARTCNGTNACNTGYCCNATHTGYYTNCARGTN CCNTCNGCNGGNAARATHACNAARTGYGGNCAYATHTAYTGYTGGGCNTGYATHYTNCAY TAYYTNAARYTNGGNGARAARGAYATHMGNAARTGYCCNATHTGYTAYGAYACNATHGAR YTNGGNGAYYTNAARAGYGTNGARYTNATHGAYGTNCCNGAYTAYAARATHGGNGAYACN ATHGARATGMGNYTNATGCARAARGCNAARGGNAGYATHTTYGTNGTNCCNAARGAYCAR TGGGARGAYMGNAARGGNAARCCNATGAAYATHGARGARGGNAAYAAYACNAARTAYATG AARYTNYTNGTNGCNTCNTAYGAYCARATHCARACNGGNGTNATHGAYMGNGARMGNATH ACNYTNACNAAYCARYTNATHGAYGCNGARGARTAYGARACNTGYTTYATHCARATGGCN YTNGAYTAYYTNMGNACNMGNGARYTNTCNYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AAYATHTGYGARTTYGGNAARGAYYTNACNCCNGGNGCNTTYTCNATHATH ACNMGNGARAGYGCNAGYYTNAARACNYTNATHYTNMGNGGNGCNAARTAYGGNYTNACN AAYGARGTNTTYYTNCCNGTNGTNTCNAAYAAYTCNMGNYTNGARAARATHGAYYTNAGY GGNTGYATHTCNYTNACNGGNTGYGTNYTNTAYGCNATHGGNGCNAAYTGYCCNAARGTN AARCARYTNATHYTNMGNGAYTGYGTNTCNTTYACNGAYGAYAAYTTYYTNTCNTTYYTN TGYGCNCARCARCCNYTNAGYYTNGARTAYYTNGAYGTNTCNGGNTGYTGGAAYYTNGGN GAYGARYTNYTNATHAARYTNGTNCARTGYTGYGGNAARYTNAARCAYYTNYTNYTNGGN AARYTNTAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYAAR ATHGTNYTNTAYAAYTAYTTYMGNAGYTCNGCNAGYTGGMGNGTNMGNATHGGNYTNGCN YTNAARGGNYTNAARTAYGARTAYGARGCNGTNCAYYTNGTNAARGGNCARCARAARACN GAYGARTAYAARAARATGAAYCCNATGGGNTAYGTNCCNTCNYTNAARATHGAYGGNYTN ACNYTNAAYCARTCNATHCCNATHYTNGARTAYYTNGAYGARMGNAAYCCNGAYCCNCCN ATGYTNCCNAARGAYAGYGCNGGNMGNGCNAARGTNMGNGCNYTNGCNGARATHGTNAAY AGYGGNATHCARCCNYTNCARAAYYTNAARGTNYTNCARAARATHGGNGAYACNAARATG GARTGGGCNAAYTAYTTYATHAAYGARGGNTTYGGNGCNYTNGARGTNATGYTNAARGAR ACNTCNGGNATHTAYTGYTAYGGNGAYGARGTNACNYTNGCNGAYGTNTGYYTNGTNCCN CARGTN---GCNGCNGCNCCNMGNTTYAAYGTNGAYATGTCNCARTAYCCNACNATHAGY MGNATHCAYAARGCNYTNGARGARYTNCCNTCNTTYAARGCNGCNGAYTTYMGNMGNCAR CCNGAYACNCCNGARGAYYTNMGNATHAAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGTCNGAYAARYTNAAYACNMGNGTNATHCARGTNACNAAY ATHGCNCCNAGYTGYTCNAARGAYCARYTNMGNACNYTNTTYGGNTAYYTNGGNMGNATH AARGARYTNGARATGTTYCCNCCNGAYGGNGCNGAR---GGNGTNGTNACNGCNMGNGTN GGNTAYATHGARTTYGARGAYTCNGTNACNACNGGNGTNGCNYTNCAYYTNAGYAGYACN GTNTTYATHGAYMGNGCNATHATGATHGTNCCNGTNATGGAYGGNAARATHCCNGAYGAR AGYTCNGCNYTNAAYYTNACNCCNTCNGCNGTNGCNGGNATGYTNCCNGGNCARCCNACN TGGCCNGCNAAYGTNGTNTCNCARGTNACNGGNYTNGGNGCNAAYCARATHATHATGACN AAYGAYCCNMGNYTNACNTCNYTNGGNYTNCCNCARTAYCCNCCNYTNCCNGCNACNACN GAYCCNAGYAARATHGARGARATHMGNMGNACNGTNTAYYTNTCNGAYYTNGAYCCNAAR GTNACNCCNGARATGYTNYTNTCNTTYTTYTCNCARACNGGNGARATHAARTAYATHMGN YTNGCNGGNGAYGARAAYGGNCCNACNMGNAGYGCNTAYATHGARTTYACNGAYCARMGN TGYATHGCNCARGCNYTNAGYTAYAAYAAYGTNGTNTTYCARGGNMGNACNGTNAGYGTN AARCAYGCNACNACNAGYATHGTNAARCCNACNCCNMGNTCNGARGCNTCNCARMGNGAR ATHGAYGAYGCNATGAARAARGTNAARGARGCNTCNAARYTNATHTCNGCNGCNGCNAAY AGYGAYMGNGAYGGNTCNATHTCNCCNAGYMGNAAR------MGNTCNAARTCNAARGGN MGNAGYMGNTCNCAYTCNAARTCNMGNMGNTCNMGNTCNMGNTCNMGN---GGNMGNMGN MGNMGNAGYATHTCNAARCCNMGNMGNMGNTCNMGNTCNMGNMGNMGNTCNCCNAARMGN TCNMGNTCNCCNGTNMGNMGNMGNMGNTCNMGNTCNMGNGGNMGNGTNCCNCCNCCNGCN CCNCCNGTNACNMGNAGYMGNGGNMGNMGNTCNMGNTCNMGNTCNMGNMGNAGYMGNTCN MGNGARMGNAARGARAARGTNAARGARMGN---------AARAARAGYMGNTCNTCNCCN CCNACNYTNATHMGNGARGARTCNGCN--------------------------------- ------------------------------------------------------------ ------AAYGCNGGNGAYGARMGNGAYGTNTCNCCNGTNAARGGNATH------GARAAR TCNCCNAGYCCNCCNAARGCNMGNAARMGNAGYATGACNCCNAARAARMGNAGYMGNTCN AARTCNCCNAGYMGNMGN---AARAARMGNMGNCAYTCNMGNTCNACNTCN---MGNAAR MGNTCNMGNTCNMGNAGYGGNTCNMGNCAYMGNTCNMGNAARGAYMGNAARCARAGYMGN AGYCAYGAY---------AGY---AGYAARAARAARAGYAGYMGNGAYAARGAYGAYAAR AARAARGARTCNTCNTCNTCNTCNAARATHAARMGNGAYTAYGAYGARGARGARAARGGN TTYGCNAGYGARGGNAGYGAYGGNGAYAAYAAYAGYGARGGNGGNGGNTCNGGNGGNGAY TCNCCNACN---GARCARCCNCCNGTNYTNGARAARGAYACNGAYCAYCARACNGTNGAY ATGGAYATGAGYGAYYTNATHMGNACNTTYCARMGNGAYCARAARGAYGGNTTYGGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNYTNGAYTTYTGYYTNCARGTNTGYTGYGGNATG GARTAYYTNAAYCARMGNCARATHTTYCAYMGNGAYYTNGCNGCNMGNAAYTGYYTNGTN GGNAARGARGARGTNGTNAARGTNGGNGAYTTYGGNYTNGCNMGNAAYGTNYTNATGGAY AAYGARTAYCAYATGTCNGARMGNTCNAARTTYCCNTGYAARTGGTCNCCNCCNGARGTN YTNCAYTAYMGNAARTAYACNAAYACNTCNGAYGTNTGGGCNTAYGGNATHYTNYTNTGG GARATHTAYTCNTTYGGNGARATGCCNTAYCARGGNYTNAARAAYCCNGARGTNACNAAR TTYGTNGCNGARAARAARMGNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNAGYGTNATGYTNGGNGTNGCNGCNGGNCAYATGTGYYTNYTNAAYCCNATH CARMGNGGNTCNATGTCNGGNATHAAYAARGCNGGNGCNGTNGAYTGYATHYTNYTNAAR GGNGCNTGYGGNGGNMGNTCNGGNTCNGARCCNACNGTNCARYTNGTNGCNGGNCARAAR CAYACNGTNATHATHCARAARAAYYTNTCNCAYTTYAAYGCNGCNGCNCCNGGNAAYTTY ACNGTNTCNATHGGNCAYAAYGAYGAYTCNTTYAARYTNYTNGCNTCNGTNGCNGAYGAY AAYGCNGCNTCNYTNTCNATHTAYTCNATHAGYGTNACNATHCCNGCNATGAARGGNMGN ATGGTNATHCARACNYTNTAYAAYACNAAYAAYGCNAARGCNCCNCCNGTNTTYCAYCAR TGYAGYGAYGTNMGNGTNGTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARATHTCNCAY ATGATHTCNTTYATHGAYCARGARGCNTGYGARAARGTNGARGARATHGAYYTNAARGCN GARGARGARTTYAAYATHGARAARGGNMGNYTNGTNCARCARTCNMGNGTNCARATHATH GAYTAYTAYGAYAARAARATHAARAAYGTNGARYTNCARAARAARATHCARAAYTCNAAY ATGCARAAYAAYGCNMGNYTNGARATHYTNMGNMGNAARGARGARTAYGTNAARGARGTN CARGARGARGCNMGNGARAARYTNAARAARGTNATHMGNGAYAAYCCNAARGARTAYGAR MGNYTNYTNTCNMGNYTNATHATGCARGCNYTNGCNMGNYTNATHGARAGYAARGTNACN ATHMGNTGYMGNMGNGARGAYGTNAARYTNATHGARAGYTTYGTNCCNGGNYTNCARAAR GARTAYAARGARYTNYTNAARGGNAARTTYTCNYTNGARYTNGTNGTNGAYCARGARAAR TTYYTNTCNCCNGARATHTGYGGNGGNGTNGARYTNCAYGCNATGAGYGGNAARATHGTN GTNGTNAAYACNYTNGAYGARMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CARCARGGNATHCARACNGCNGGNAGYTCNAGYCCNGCNGCNGGNACN GCN---GCNGGNATHCCNCARATGYTNTTYYTNAAYCARGTNACNATHAAYGGNCARACN TCNTTYGTNYTNGTNGAYGCNCARAAYAARCCNATHCARYTNCCNCARGGNATHCARGTN ATHAAYTTYCCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGGGNAARAARCAYAARTAYGGNAARCAYTCN TCNTCNTCNAGYAGYTCNTCNAGYAGYAGYGAYTCNTCNGAYGAYGARTGGMGNCAYYTN CCNAARCAYGARAARAARATGMGNAARAARTGGAARAARAGYATGMGNACNGGNAARGTN CCNCAYGGNCARATGCCNCCNTGGAGYGGNGGNCCNGCNTGGGCNCCNCCNATGMGNGCN GGNAARAARGGNCAYAARGGNAARGGNGGNGCNGTNCAYGGNGGNGCNTAYCCNGCNGGN GGNGCNGCNGGN------GGNTAYCCNGCNCCNGGNTAYCCNGGNCCNCARCCNGGNTAY CCNGCNCARCARCCNGGNTAYCCNGCNCARCARGGNTAYCCNGCNCCNCARCCNGGN--- TAYCCNGCNCCNGGNTAYCCNGCNCARGGNTAYCCNCCNCARCARCARGGNTAYCCN--- ---GCNCCNCARGGNGCNTAYCCN---GGNGCNGCNCCNCCNGGNGGNTAYCCNGCNGGN GGNCCNCCNCCNCCNGGNCAYTAY---GCNCCNCCNGGNGGNGCNTAYGGNGGNCAYGGN GCNCCNGCNGGNCCNTTYCARCCNCCNCCNGGNGGNGCNTAYCCNCARCCN------GGN TAYCCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARATHTCNTCNGAYAARCCNATHGTNYTNMGNAAYGGNYTNGTNGCNMGNAARACN YTNGCNMGNMGNGCNAARACNGTNMGNTAYGARAAYMGNAARMGNTCNTCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARGGNTGYCCNATHCCNTTYMGNYTNATG MGNGARTGYGARGGNGTNAARGARGGNGTNGTNCCNYTNTCNMGNGAYGGNYTNGTNTGY ATHAARGARAAYMGNTGYTAYAGYCCNGTNTGYACNGTNGGNGARTTYGAYGTNAARACN GGNTTYTGYCCNYTNTCNGAYATHTAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------MGNATHCARMGNGARYTNCAR GARATHTCNAARATHAARAAYGARAGYGGNATHGGNCARGTNATHTAYAARGARYTNGAR GGNYTNMGNGCNAARCCNCAYCARCCNYTNGAYCCNTGGAARGCNTCNMGNGCNCCNAGY GCNAARTTYGARCCNMGNTAYMGNACNMGNTTYCARTCNCCNATGTTYGCNTCNCCNTCN MGNTTYYTNGAYMGNCCNMGNTAYGCNTGGGAYGAYAAYGAYATHMGNGCNTAYMGNTCN GCNTCNACNYTNGCNAAYYTNCCNACNCCNAARCCNGGNTAYGGNCCNTCNTAY---ACN CCNMGNGCNGCNACNYTNCCNYTNTCNGGNGCNTAYGGNGCNMGNGAYGAYTTYMGNTTY TTYGARTTYGAYGARTCNGAYGAYMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNTTYGCNYTN TTYGGNAAYGAYYTNTAYGAYGGNAARTCNGAYGCNAARGCNATG---AAYATHTCNTTY GGNCARMGNGAYGAYGGNGGNTAYGTNAARTAYAAYTAYACNGTNTGGACNGCNGCNGTN GGNTAYGGNACNCCNCCNAARGAYGARATHTCNATGACNGTNATHATHATHATHTCNGCN GGNYTNGGNYTNCCNGTNYTNATHATHATHYTNGGNGGNATHTTYACNTTYGTNMGNMGN MGNMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GGN ACNTTYTGYYTNYTNGARGGNTCNCARTCNGCNGCNCARTTYTAYGTNTTYGTNGGNGTN ATHGTNTTYYTNTAYTGYYTNGGNGCNYTNGTNYTNTAYGTNTTYTTYGAYGARYTNTAY MGNMGNAAYACNMGNATHGTNGTNATHGAYTTYGTNATHTCNTGYGTNYTNACNYTNTTY TGGATHATHGCNTCNTCNGCNTGGGCNGCNGGNYTNGAYGAYGTNAARYTNTAYACNGAY CCNTCNGAYGGNGGNATHTTY---GGNTCNGTNCARGARTGYCARGARAARAAYGCN--- TGYTTYACNGCNAAYGGNGGNAAYTTYGCNAGYYTNAAYGTNTCNATHATHTTYGGNTTY YTNAAYTTYGTNGTNTGGATHGGNAAYYTNTGGTTYYTNTTYAARGARACNCCNTGGTTY AARGTNCARGCNAARCCNCCNAGYCARCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ACNTAYTCNTGYGTNTAYMGNMGNATHGCNTTYGGNCARAAYYTNTCNYTNCAYATHGTN ATHAAYCCNYTNCARCCNTCNGGNYTNCCNGARTGYMGNYTNYTNGGNGCNGARCCNGCN GTNGCNCCNYTNMGNGARAARYTNAAYGTNAAYYTNCAYCARTGGGAYYTNGAYMGNTCN YTNYTNAAYAAYYTNCARGARGTNYTNGARATHGAYTTYCCNACNCCNTCNGAYACNATG AARGARGARYTNAGYGTNGARTGYGGNATHTGYTAYAGYCAYCARYTNGARGARGARATH CCNGAYATHGTNTGYCARTAYCCNCARTGYAGYCARGCNTTYCAYTAYACNTGYYTNTAY GARTGGYTNMGNAAYTCNTCNTGYMGNCARAGYTTYAAYTAYATHTTYGGNGARTGYCCN TTYTGYAGYAARCCNATGMGNGTNAARATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CARCAYCAYYTNGAYCAYCAYCAYCAYTCNTCNCAYTTYGAYCAY CAYTCNMGNCAYCAYGAYAARACNAGYGARGGNGGNTAYGGNGCNTCNTAYAGYGAYTCN GGNYTNGAYGCNGCNAARMGNMGNACNYTNCCNYTNTGGYTNMGNGARGGNYTNGARAAR ATGGARMGNGARAARCARAARAAYYTNGARAARGARCARATGAARCARAARCARAARGAR ATGYTNGAYATGCARGARAARGARNNNACNGARGAYGAYGARGARGARGARGAY---GAY GAYGGNCARCCNAARGTNCCNMGNAARAGYMGNTTYGARTCNGAYGAYGARGAYGARGTN GCNGAYAAYAARGCNGCNGARGARGAYGAYGTNGTNAAYGAYAGYGGNGGNGARGCNTCN MGN------------------TCNCARTCNCARGARMGNTCNTCNAARGCNTCNCCNAAR MGNAGYCCNTCNCCNACNGARTAYATGACNGARGARGARAARGARYTNGCNYTNATGATG AARGTNAARMGNYTNYTNACNGARACNYTNYTNGCNGTNACNGAYCARGARATGMGNAGY ATHGCNTCNGARGTNTAYCARMGNGARAARAARAARGCNYTNAARGCNCCNGCNAARCAR YTNGCNAARTCNTCNGCNYTNGCNTCNYTNTCNACNYTNGGNYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNTCNGGNGCNAARTAYGTNGCNATGGAY AARTTYGARAARGTNTGYGTNGARYTNTCNGGNGCNYTNMGNMGNGARCARAARGCNCAR GTNYTNYTNCARGARCARAGYAAYCARYTNACNGARYTNACNTCNMGNYTNGAYATGTGY GCNTCNGAYGGNGTNCAYAARGARAARAGYYTNGTNCARGTNCARGARGGNATGAGYGAR ATGCARGGNCARYTNMGNCAYAARGAYCARAAYYTNMGNCARATHGGNAARCARYTNGCN CAYATHGARTAYGARMGNGAYTCNYTNCARAGYAAYYTNAARGAYGCNGARAGYGCNYTN MGNACNGCNGCNMGNGAYAARGARATHGTNGCNCARTAYATHAARAGYGTNGGNAAYGCN YTNGARTCNGCNAARAARCARTTYYTNATHATHAGYGARCCNCCNCCNYTNTCNAARGAY GTNTCNYTNTCNMGNYTNYTNYTNGAYGCNGAYYTNATHCCNYTNGAYATHGGNAARGCN GGNCCNGARYTNATHGCNYTNCARAAYYTNGTNGGNGGNTTYGTNGAYGCNCARCAYCAR GCNGTNAAYAARATHMGNTCNYTNGARGARGARATHGCNTCNCAYMGNAGYCAYATHGAR TCNYTNAARAARGARYTNAGYAAYGCNGTNCARMGNGARTTYAGYCARCARYTNGCNTCN GCNACNGAYGGNGAYTTYTCNCARTTYACNGAYCARGARGARGAYYTNGTNCCNYTNAAR GARGAYCCNGAYATHTCNTTYGARAGYYTNCCNACNCCNMGNAARATGACNCCNCCNATH TCNACNACNYTNAGYCAYCCNTCNATHCARCAYAARAARTCNGCNTTYCAYTCNGTNAAR TCNAGYAGYTCNATHACNYTNAGYGCNATGGTNGCNGGNGCNGCNGCNTAYAAYCCNTTY ATHACNTTYTAYATHAAYCCNCAYAAYYTNTCNCCNGAYTAYACNTTYCARGAYACNCAR TAYTTYTCNGAYAARGAYYTNYTNGAYMGNGTNCCNTCNACNTTYYTNATHYTNGGNACN GTNTCNYTNGTNATGCARATHGTNGGNTTYTGYATGYTNMGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYCCNATHCCNTCNGARCAYGGNAGYAARAARAAR TGYGCNGAYGGNAARTGYGGNAARGGNTCNGAYACNCCNGTNGCNGTNATHGTNGTN--- GTNGTNYTNYTNATHYTNACNYTNGTNTGYGGNGTNGCNGGNTGGGTNTTYTAYGCNTAY ACNCAYCCNACNTCNMGNTCNGGNATGTGGYTNATGGARCAYMGNCCNAGYCARATHAAR GCNAARATHAARTTYTGGAARAGYAGYAGYAGYTCNGGNGCNAARTAYMGNGCNGARACN GAYGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHGGN MGNGGNCARCAYYTNTAYAAYAARCARAAYYTNGARTCNTCNATHTTYAARAARTAYTTY CCNAAYACNCCNYTNGTNGGNTTYTTYGGNAAYGGNGARATHGGNTGYACNTTYCCNCAR CCNGGNYTNATGCCNGCNCARAARAARGTNGAYAARAARGTNGCNAAYGCNGARGGNAAR ---------------YTNTCNTCNGCNCARATGAARMGNCAYYTNGCNGAYGTNAAR--- ------------------------------------------------------------ ---------------------------------------------------YTNTCNYTN CARGARYTNTGYTCNAGY------ATHCAYGARCARAARCARAAYYTNCARACN------ ---------------------------------CARGAYCARGAYGTNCARMGNYTNTCN MGNAARACNCARAAYGTNYTNATGAARCAYAAYACNYTNGARMGNGCNYTNGARGCNGTN GARAGYMGNTCNTCNAARGAYGARGGNCARAAYGCNGAYMGNAARGARGARACNATHYTN AARATHGCNAARYTNCARACNGARYTNGCNAARACNGGNGTNACNGARTCNAAYTTYCAY GAYAARYTNATGAARAARMGNGARMGNYTNGARAAYYTNGAR------------------ ---------------------AGYGARYTNTCNCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARATGGCNYTNGCNTCNGTNGCNGCNAGYTTYGTNYTNYTNYTNGCNYTNACN GTNTCNAAYACNMGNACNYTNGTNTTY------TCNAGYTGYCCNAAYCCNGGNAGYCAR GAYAGYTTYGAYGTNAAYCARTAYYTNGGNAARTGGTAYGARYTNGARMGNTTYAGYGCN ATHTTYGARYTNGGNGTNATHTGYGGNACNGCNGAYTAYAGYYTNAAYGAYGAYGGNAGY ATHAARGTNATHAAYGGNGGNAARMGN------MGNATHYTNGGN---------ATGGAR AGYCCNACNTCNGTNACNGGNAARGCNACNGTNCCNGAYTCNTCNMGNCCNGCNGARYTN MGNGTNTCNTTYTCNMGNTTYGAY---CCNGGNACNGGNCCNGCNAAYTAYTTYGTNGTN GAYACNGAYTAYACNACNTAYACNGTNGTNTTYTCNTGYACNGAYYTNYTNGGN---CCN YTNAGYATHCARTAYGCNTGGATHYTNACNMGNGARMGNGGNGTNGCNCCNGGNAAYYTN GCNGCNYTNAARTCNAAYYTNGARTCNCAYGGNGTNCAYYTNAGYAAYTTYAAYCAYGTN GAYCARTCNGAYTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MGNAARTTYGGNTTY AARGARGTNTCNGAYGAYGARGAYTGGACNYTNTAYTGGACNGAYTTYTCNGTNGCNYTN GARMGNGTNATGGARATGAARAAYTAYCARAARATHAAYCAYTTYCCNGGNATGAAYGAR ATHTGYMGNAARGAYATGYTNGCNMGNAAYYTNAAYMGNATGCARAARGCNTAYCCNAAR GARTAYAAYGTNTTYCCNAARACNTGGTGYYTNCCNGCNGAYTAYGGNGAYTTYCARGCN TAYACNMGNCARAARAARAAYAARACNTAYATHYTNAARCCNGARTCNGGNTGYCARGGN AARGGNATHTGGGTNACNAARAAYCCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GTNGAYTCNGAY TTYGARGAYCARGAYGCNYTNCAYAAYGCNATHGAYTGGTAYMGNAARGGNTTYGARGTN CARCCNAAYGARTAYGCNGGNATHAAYYTNGCNACNYTNYTNGTNATHTCNGGNAARGAY TTYTCNACNTGYGCNGARYTNCARMGNATHGGNATHACNYTNAAYAAYYTNATHGGNAAR AARGGNAGYYTNTCNTCNYTNACNAAYTAYTGGGAYGTNGCNACNTTYTTYGARATHAGY GTNYTNGCNGARGAYTAYAAYAARGCNGTNCARGCNGCNGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNACNTGGTGYMGNAGYATGATGYTNACNMGNACNYTNMGNCAR GARGARGGNGARGCNGARGARGTNACNGAR---------GCNCCNAARMGNAARGTNGTN GAYGTNGARACNAGYATHMGNTAYYTNAAYAGYAARGCNTTYGTNGARGGNTAYGGNGAR AARCCNGTNTGGTTYTAYTAYMGNMGNAAYTTYAARGGNACNYTNATGCCNCCNACNMGN AARACNTGYATHMGNAARGGNGARYTNGCNACNTCNAGYCCNTGYCCNGTNTGYMGNGAY GARTAYYTNGTNYTNGGNGCNAARAAYACNAARYTNYTNGAYCARTTYATHTCNCCNCAY ACNGGNGARATHTTYGAYTCNATGGAYACNGGNYTNTGYCARATHCARCARMGNAARYTN ATGGTNGARGTNATGAARGCNTGGGAYCARGGNTAYYTNGARATGAARGTNCCNTTYMGN ACNTAYAAYTAYGAYGAYTAYAARAGY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TAYYTNTCNACNATHGARGCNATHTAYTAYTTYTTYAARGAYTTYCAYACN ATHTTYYTNGAYCCNGTNTAYMGNAAYGARTAYGAYAAYYTNYTNTTYTTYTTYTGYTTY TTYTTYGAYAARATHAAYMGNCCNAARAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNAARGARATGGARGARGARMGN GAYCARYTNGTN------AARGAYCARAARGAYATHCARATHAARGAYYTNCARGARMGN YTNGCNATHYTNGCNMGNGARAAYGARGARAARGAYGARMGNATHAGYAARYTNACNGAY AARYTNAAYGARACNTCNAAYAARYTNAARGARACNGARMGNMGNYTNATHATHTCNGAR GARGCNAAYGCNGCNAAYCCNGARGCNCCNAARTCNAARACNTGYGCNATHATG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNTTYAARAGYGAYGTNAGY YTNGAYAARYTNTAYCCNAAYTCNAAYCCNGAYTAYYTNMGNCCNAARCAYGAYMGNAAR GAYCCNATHACNAAYGCNGARYTNTTYTCNGGNCAYATHCCNGTNGARCARYTNGAYGTN AGYCAYAGYMGNAGYTGYGGNCCNGGNGGNCARAAYGTNAAYAARGTNAAYAGYAARGTN GAYATGMGNTTYCAYYTNGGNTCNGCNTCNTGGATHCCNGARTGGATHAARCCNAARYTN GCNGAYCARGARCARAAYMGNATHAAYAARGAYGGNTTYYTNATHGTNAARTCNGAYATG ACNMGNAARCARATGYTNAAYCARGCNGAYTGYYTNAAYAARYTNMGNAAYATGATHTAY AARGCNTCNGTNGTNCCNGARGARCCNTCNAARGARGAYATHGCNAARMGNGARAARMGN ATHATGAARGCNAARTCNGARGCNYTNAARGGNAARAARMGNAARTCNYTNYTNAARMGN TCNMGNTCNAAYCCNGARYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNGARTTY CAYGGNYTNTTYCCNYTNGCNTGYTGYYTNAAYCAYTCNTGYTTYCCNAAYGCNGARATH GARAGYGCNGAYGTNGARGGNMGNCCNGGNATHGTNYTNAARGCNGTNMGNGAYATHAAR GCNAAYGARGARGTNGTNGTNTCNTAYGTNGARCCNYTNGARGARMGNCAYGARMGNMGN GGNAARYTNTGGMGNAARTAYAARYTNATHTGYGAYTGYCCNMGNTGYTGGTAYGARGGN GTNGGNCCNCAYGTNTGYACNAAYTGYGCNAARCARGCNAARGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AARGCN GTNCCNATHYTNYTNAARTCNATGAAYACNTCNAAYYTNAARTAYACNGARGCNGTNYTN MGNTGYYTNMGNTCNATHTTYATHGARAAYACNGAYGGNATHGAYTAYYTNTAYGARGAR AAYACNTAYGGNACNTCNTAYATHCCNACNTTYYTNGCNATGACNCARCARTCNGCNGTN TGYCARGARTGYGTNACNAAYATHYTNGTNTGYGGNTGYAARACNMGNGARCAYCARATH TGYYTNYTNAAYAGYCARGCNYTNCCNACNYTNTCNCCNYTNYTNCARTCNAAY---CAR TAYAARATHCARATGCCNACNYTNMGNTTYTTYGCNAARATGTGYTAYAARAAYCAYGAR GTNTGYTCNGCNATHGCNCARGAYAAYAARYTNATHTCNACNTTYGTNMGNYTNATGGGN MGNGAYAARCCNACNGARATGCARATGTCNGCNGCNGARATGYTNACNAAYYTNCAYMGN TGYGGNGTNATHCCNTCNAGYGAYTTYATHATHAGYMGNAARACNYTNGGNACNYTNGTN MGNATGTGYATGMGNGAYCAYACNGTNGARGARAAYGTNMGNGGNGCNGARGTNYTNGCN TAYYTNGTNGARATHGARCCNGAYYTNCARGTNACNGCNAGYTAYACNGTNCAYYTNATH GGNGCNYTNTCNACNTGYYTNCAYTAYCARGAY---------------AAYAGYAGYCAR CARGAYGTNGAYTGGGGNAGYGARATGMGNMGNGCNGCNTTYYTNGCNTTYGCNTCNATH AGYGCNAAYGAYGARGARATHMGNGARAARGTNATHAARCARGAYGGNATGATHGARCAY ATHCARACNGCNYTNTCNAGYAAYCAYGARGGNGARGTNGCNGCNAGYYTNMGNTGY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TTYATGYTNYTN TTYAARGAYYTNATHMGNYTNTTYGCNTGYTAYAAYGAYGGNATHATHAAYYTNYTNGAR AARTAYTTYGAYATGAAYAARAARCARTGYAARGAYGCNYTNGAYGTNTAYAARMGNTTY YTNGTNMGNATGGAYAARGTNTCNGARTTYYTNAARGTNGCNGARAAYATGGGNATHGAY AARGGNGAYATHCCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGGCNGGNCARCCNAARTCNGGNATHACNGCNCAYTCNGAYGTN AAYYTNGAYTTYYTNACNAARGARGARMGNGARGCNYTNYTNTCNAARAARATGGAYATG ATHMGNCARMGNAAYMGNATGATHACNGARMGNCAYGARATGATHGARGCNGAYMGNMGN AARGCNGARGARTCNGGNAAYGCNGTNAARGCNYTNGAYAGYAARACNYTNCCNGCNGAR GGNGCNTCNAAY---AARCCNMGNGGNMGNGGNMGNGGNCARGTNCAR------GGNGCN CAYAARGAYAGYAAYMGNCCNATGAARGAYMGNCCNAARTCNCAYGGNGAYGCNTCNTCN TAYGARCCNATHGTNGAYGTNAGYGAYYTNAGYGGNCARMGNACNGARAAYMGNAAYMGN GGNMGNGGN------CARCAYCAYYTNGAYMGN------------------GAY---GGN GGNCAYGTNTCNACNCCNAARAAYMGNMGNAARCCNCARTCNAARGAYGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHGAYGCNAAYGGNCCNMGNCCNGARCCNGTNTAYYTNMGNMGNGAR AARCARCARCCNCCNAGYYTNGTNGCNTCNAARCAYCCNCAYGGNACNAGYCCNACNAAY GGNAGYCAYCCNCAYACNGGNCARCCNMGNCCNYTNMGNTAYGGNAAYGAYAAYAGYAGY GTNAAYMGNCARTCNMGNACNCARAGYACNMGNCCNGAYCCNATHCCNGGNCARCCNTAY GCNGGNGCNCCNGCNCARMGNYTNGGNAGYGCNCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNGTNMGNGGNCAYGTNYTNCCNYTNGCNYTNCARATGTAYGGNTGYMGNGTNATHCAR AARGCNYTNGARTCNATHCCNTCNGAYATGCARGTNGARATHGTNAARGARYTNGAYGGN CAYGTNYTNAARTGYGTNAARGAYCARAAYGGNAAYCAYGTNGTNCARAARTGYATHGAR TGYGTNGAYCCNGARTAYYTNCARTTYATHATHGAYGCNTTYAARGGNCARGTNTAYAAY YTNTCNACNCAYCCNTAYGGNTGYMGNGTNATHCARMGNATHYTNGARCAYTGYACNGTN GARCARACNCARCCNGTNYTNGAYGARYTNCAYGARAAYACNGAR--------------- ---------------------------------------------------ATGAGYACN TCNGTNGGNACNATGMGNGCNGGNTCNAAYAARATHCCNGGNCCNAARGAYAARCCNGCN AARGGNGAYAARAAYACNGCNTCNCARCARGCNACNGTNGTNAARTCNGARGTNCAYTCN AAYAARATGCARCCNACNCARGARCARYTNMGNYTNGCNCARATGATGAGYACNAAYCAR ACNGAYGCNGAYCCNAAYACNGTNAARCARYTNATGGAYATGACNGGNAARAGYGARGAY GTNGTNGTNATHGCNYTNCAYGAYGCNGGNAAYGAYGCNGAYMGNGCNGTNATGYTNYTN YTNGARGGNGGNAAYGARCARGGNGARTGGYTNGARCARGGNGGNAARAARAARAARAAR ---AAYACNCARAARGAR------AAYACNGTNAAYGARGAYCARACNGARGGNMGNAAY AARGAYMGNGGN------------GCNGAYAARAGYGGNGAYCAYCARGAYYTNCCNCCN MGNMGNGGNMGNMGNAAYGGNGGNCCNCCNCCNMGNYTNGCNMGNGGNMGNGGNMGNGAY AARGGNACNTTYGGNGAYMGNGAYAARGAYAARGARMGNAAYAAYGCNGARGAYTGGGAY AAYGAYAARGAYGAY------AARGGNCCNMGNAAYGAYMGNGAYMGNAGYGGNGGNGAY MGNGGNMGNTCNMGNGGNMGNGGNGGNTTYGGNGGNAGYAARCCNGGNGGN--------- GGNGGNMGN---GGNMGNTTYAAYAAYAGYAAYGAYMGNGARAAYMGNGGNTAYAAYAAY MGNCCNMGNTTYGARAARATGAAYAAYTCNCARCCNTCNGARGGN------CCNGARATH GAYACNTGGATHAAYGARGCNGCNGARACNAAYGTNACNAAYAARGAYACNGAYTGGAAY AGYTGGAGYGAYACNTGGGTNAAYGARGARGAYCARTGGACNGGNACNYTNGARGARACN AARGTNTTYACNCCNTCNCAYGTNAARATHCCNGARCCNGARCCNATHAAYAAYGARCCN CCNAGYTCNYTNGGNCARMGNYTNGAYGTNGGNAGYYTNTTYGARAAYGCNAARTTYACN AARGCNCCNGAYTAYAGYAARCCNAGYGGNGAYTCNTAYATHACNCARTTYAAYCARGCN GCNACNGARTCNATHAARAAYACNATHGGNATHGGNAGYACNTCNMGN---CCNCAR--- ---------ATGGGNATHTCNCCNCARAAYTCNTCNAGYTCNYTNGGNYTNTCNAAYYTN GGNCARAGYCCNGGNAARGTNCARGGNAGYGCNGTNYTNYTNCCNYTNCARCARTCNAGY TCNCARAAY------TCNATGCCNCAYGCNATHGCNCARYTNACNCARATHTCNCARCCN GCNTCNCARTCNCCNAGYATGTCNCARATGGGNATGGGNTCN---CARCCNAGYCARGTN AGY------------------------------------------------------AAY AAYCARGCNCCNCARCARTCNMGNATHCCNACNGTNATH------------------CAR CARCARCARAAYYTNCCNCARACNAGYATG---AAYAGYATGCARCARMGNCCNAARCCN CARMGNTCNAARYTNCCNCCNCCNTCNAARATHCCNTCNACNGCNGTNGARATGCCNGGN CAYATHCCNMGNAAYCCNCARYTNGAYGTNCARTTYGGNYTNGAYTTYGGNTCNGARCCN TCNGTNCARTTYGGNTTYGGNGGNAGYGGNGAYAGYACNGCNGTNACNAGYTCNTAYTCN ACNACNTCNAAYGGN---ACNACNGTNATHTCNAAYCAYYTNAAYCARGGNCAYGTNAGY CARTCNGCNGGNGAYGGNAAYTCNGTNCCNAGYATHATGCCNTCNCCNTCNGCNGGNTCN GCNAARGTNCCNTCNGGNATGGARCCNCARGTNTCNAAYMGN---CCNGGNGTNTTYCAY AAYTCNGTNTAYTCNTCNCCNCARCARAARAAYGARAGYCARGCNYTNGARMGNGAYCAR AAYAARGTNAAYGAYTCNATHCCNTTYYTNTCNTCNCARATGGARMGNAARACNAGYCCN ATGACNTCN---CARMGNCCNGGNCARACNAAYCARAAYYTNAAYACNGGNCCNATGACN TCNAAYAARAAYGAYCCNCCNAGY---GCNGTNGCNAAYAGYTAYTCNTCNGCNAAYGGN TAY---ACNTCNTCNTAYCARAGYCAYCCNAARGGNTCN---------------CAYACN GCNAAYTCNCARCCNTCNCARACNTCNTCNTTYCCNGGNCARTAYCCNGTNAAYCARTCN ---TAYCCNACNGCNGGNCARACNCARTTYCCNGCNCCNCCNAAYACNACNCCNTTYCCN TCNGCNCARCARGCNCARTAYAAY---------TCNAAY------TCNTCNCARAAYCAR TTYTCNGGNCARAAYCARTAYTCNGTNGGNACNTCNACN---------ATHGCNCAYCAR AAYCARTAYCCNCCNAGYGGNCARAAYAAYTAYGGNAGY---GGNCCNTCNCARTAYTCN GCNTAYCARAAYAAYACNTCNTTYCCNTCNCAYCCNCARACNCARTCNAAYTAYCCNTCN AAYCARAAYGGNGGNACNGGNGCNGTNYTNTAYCCNACNTCNACNCARTCNGGNGTNCCN TCNTAYACNGCNCARTCNAAYTCNTAYCARTCNCCNTCNGCNGGNTCNTAYCAYTCNTCN MGNGAYGGNCCNACNAAYGTNGCNGTNAGYACNCARTCNAAYAGYGGNATHTCNTTYCCN AGYCARCCNCARAAYTCNAAYYTNAARCCNGTNGTNACNCARAGYAAYTCNAGYTTYAAY TCNCARAGYTAYAAYGCNACNCCNACNCCNATGCARCCNTCNTCNYTNGCNAAYAARYTN GGNGARGGNYTNTCNAARATHTCNATHAARGAYTCNTCNACNGTNYTNGAYAGYCAYCAR TCNTCNCARTAYGARCAYACNCCNTCNGCNGCNAGYGTNCCNACNAGYGTNAGYYTNCCN TCNGCNTCNGGNTCNGCNTCNYTNTCNACNGGNACNAAYACNATHYTNTCNACNTCNACN GTNACNTCNGTNTCNTCNAAYTCNMGNGTNGCNTCNATGCCNTCNACNTCNGGNAARGCN CCNCCNAAYYTNCCNCCNGGNGTNCCNYTNATGGGNCARTAYATHATGGGNCARAGYACN ATHCCNCCNTTYTAYAGYGTNCARCCNCCNYTNTAYGGNTAYGARGAYGTNCARYTNYTN CARCARMGNATGCCNATGCARACNGGNAGYTTYTAYGAYGTNAGYGCNTTYCCN---GGN CCNGCNGGNTCNACNYTNTCNGCNAGYMGNGARCARCARCCNCCNATHCCNAAYGTNCCN TTYTCNGGNACNTCNGAYACNAARATGACNMGNGTNGAYGCNCARAGYCCNAAYGCNGCN AGYCARCCNCARAGYGCNCAYTCNGCNGCNCARCARCCNYTNTTYAAYTTYCAYTAYGGN TAYTAYTAYCCNTCNATGTTYCCNGGNGCNGCNGGNYTNCARTAYCCN---GCNGTNTAY CCNATHCCNCCNGTNACNAAYGCNGCNGCNCAYCCNGGNACNACNTCNACNACNCARTTY CARAARTCNTAYCCNTCNCAYGTNTAYACNACNAARGGN--------------------- ------------------------------------------------------------ ---------------TCNGGNACNAAYGARATHACNGCNAAYGCNTAYAGYAARTCNCAY GGNCAR---GGNTTYGAYAARCARGGNTAYCAYGGNGGNACNCCNCCNCCNTTYAAYYTN CCNYTNGCNTCNGCNGCNCARACNGGNCCNATGGGNGCNCCNGGNACNCCNTAYGGNGCN CCNTTYYTNCCNGTNATGGCNGCNCAYCARCCNCAYTCNCARATGATGCAYCAYCCNATH CARCARGAYTCNAAYAGYAGYAGYTCNMGNGGNYTNAAYCCNGCNGGNGGNCARGGNAAR TCNGGNACNGCNAARTCNTTY------GCNCCNCCNTAYTGGAAYAAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARTTYGTNTAYGTNGTNGTNGAYATHACNGCNTTYTTYYTNATHTTYGTNGCNGCN TGYATHYTNTCNGCNGGNACNAAYGAYACNTGYGAYYTNGTNAAYTGYGAYCAYGAYTCN TTYTCNGAYGCNTAYTCNGCNTCNAARGCNGCNCARGCNGGNGCNTGGATHAGYACNTTY YTNTGGYTNTTYATHGCNGTNGCNGGNTTYATHACNYTNTGGMGNGCNGGNAARATHCCN TTYYTNGGNGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CCNCARGTNGCNAARGAYGARGARCAYATH GCNAAYGCNGTNAAYCARATHYTNGCNCARGCNGTNCARCARCARMGNGARYTNAGYYTN GCNGCNCARAAYCARCCNCCNCCNCCNCCNAARAGYMGNAAYMGNAARATGGAYTCNAAR TTYCARTAYMGNATHMGNMGNMGNYTNTAYCAY--------------------------- GGNGAYGARGCNAAYYTNAAYACNCCNTCNYTNCCNYTNACNGARGCNTCNGTNGARTAY TTYCARGAYAGYTTYCCNGGNGCNGARGGNYTNGGNMGNYTNGAYATGCCNATGGCNGCN AAYGTNAGYAARMGNAAYAARGTNTCNCCNTGYTCNGTNGTNATGTCNATGYTNTAYGCN AARMGNYTNMGNCARMGNAAYAARGARTAYYTNCARTCNATGTCNTCNACNGAYGTNTTY TTYATHTCNATGATGATGGCNAGYAARTAYATGTAYGAYGARGGNATHGAYGARGARGTN TAYAAYGAYGARTGGGCNGAYAGYGTNGGNCARGARGTNGARGAYGTNAAYCARATGGAR ATGGAYTTYYTNAARGARATGGAYTGGCAYYTNTTYGTNAARCCNGARGARTTYGAYCAR GCNYTNACNGCNATHGARMGNMGNYTNGCNYTNAARGARGGNGTNAARMGNGGNTGGTTY ACNTAYACNGARYTNGCNGTNYTNYTNGAYTGGGAYCCNGTNTTYAAYYTNTGGAAYCAR GTNGGNYTNGAYTGYACNAARGTNGTNTCNYTNTTYTCNGCNGTNTAYGTNGCNAGYYTN GTNAGYATGATGGGNTCNGCNGCNATHGCNYTNCARYTNTCNGGNCCNATGGCNACNGCN ACNYTNGCNGTNYTNTCNTTYCARTCNTCNCAYYTN------------------YTNGCN TGGAARTGYTGYCCNMGNTCNTGGAAYTAYCARTGYYTNAGYAGYAGYGTNMGNCARCCN TGYTTYTCNTAYTAYTAYCARGGNGTNMGNGARTGGTGYTGYCCNATHTGGCCNTCN--- ---GTNTTYATHMGNAARTGYAAYTGYAGYCARTGYGCNATHYTNACNTCNACNTGYGCN AAYGARGGNMGNTGYCARMGNMGNTAYTCNAARMGNAGYTTYYTNGCNGTNTGY---TAY MGNAAYTAYCARTGGGGNTTYYTNMGNTAYATHACNAARTAYYTNCCNTCNAGYTGYTAY TGYMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGTNTGYGTN CCNTGYTTYYTNATHCCNYTNATHYTNTGGGTNTTYCAYAARTTYATHCARCCNTGGYTN TCNAARATHTGGGGNAAYTCNGARAAYTAYGTNACNAGYAAYYTNACNTGYCCNYTNCCN AARAARAARAARCCNGTNAAYAGYCCNGARACNAARGAYGGNGARACNAGYAARGARAGY GTNGARGARAAYGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CAYCCNGAYGGNAARGARATGCARATHAAYYTNACNGGNTTYYTNAAY GGNAARAAYGCNMGNATHTTYGTNGCNGARYTNTGGGARCAYYTNTGYAGYGCNCARGAR AAYATHACNGGNATHCCNAAYGARTTYYTNGARCARAARAARAAYGARATHAARCARMGN CARGARGARCARGARMGNYTNCARGARCAYYTNAARAARAARGARGARCARATHAARGAR CARYTNTCNMGNGARMGNMGNGARYTNGARAARAGYATGAAYAAYCARTCNCCNGAYMGN CCNCCNAARAGY------------------------GARAGYAAYGGNGTNAARCCNYTN ------GAYGGNGGNGAYGCNGTNGAYTCNAARACNGARACN------------------ ---------AARACNGARCARAARGAYGGNACNGARGCNGARGGNGARCCNCARGCNGAR GCNAARAARGARTCN------------AARGARMGNGARAARACNCCNGARAARAARNNN GARCAYMGNGAYMGNGAYMGNMGNMGNCAYTCNAARACNCCNGARMGNCAYMGNMGN--- ------CARAGYCCNGAYMGNCAYMGNMGNGAYMGNGARMGNGAYMGNCCNAAYTTYAAY MGNGGNMGNTAYTCNCCNATH------------------------MGNMGNMGNTCNMGN TCNCCNMGNMGNMGNTCNCCN------------------CCNCCNCCNMGNMGNMGNAGY CCNCCNCCNMGNTCNGCNTCNCCNCCNCCNMGNMGN------MGNTCNCCNAARAARGCN GAYGAYGCNAARAARAAY---------MGNTCNAGYTCNGGNAGYAGYTCNAGYGGNTCN GAR------------AARTCNGCNAARGARGAY---TCNTCNCCNGAYAARGGNGGNATH CARCARMGNMGNAAYTAYMGNAARCAYGAYGAR---AGYGGNAARGARTCNAGYTCNGAY TCNTCNGGNGAYGARAARCARMGNAARAARCCNTTYCCNCCNCCNAARGAYMGNMGNTTY AAYMGNAGYCCNTCNCCNMGNMGNMGNMGNAGYCCNMGNCCNAGYCCNMGNMGN------ ---CARAGYCCNCCNMGNMGNMGNTTYCARTCNCCNCCNMGN------------------ ------MGNMGNATGAGYCCNATGMGNCAYMGNTGGAGYCCNTCNCCNMGNMGNMGNTCN CCNCCNMGNCAYTCNCCNCCNMGNMGNMGNAGYCCNCCNCCNCCNMGNMGNMGNATGTCN ATHTCNCCNMGNMGNMGNMGNAAYTCNGGNTCNCCNCCNMGNCARATGTCNCCN---CCN MGNMGNGAY---MGNMGNCCNGCNTCNMGNTCNCCNTCNGGNTCNCCNGTNAARMGNMGN CCNTCNCCNCCNCCNGTNTCNCCNCCNGCNMGNTCNAARAARAARCARGCNCCNGCNCAY CARTCNGARTCNGARGGNAGYTCNAGYTCNGARGAYTCNTCNTCNTCNCCNCCNCCNCCN GCNAARMGNGCNGTNCCNGGNAARGAYCARCCNTCNAARMGNCCNATHCCNCCNGCNAAR CCNGCNAGYGAYAGY------------------------------------GARAGYGGN TCNTCNTCNTCNGARTCNGARGAY---AGYGARGARGGNTCNGCNTCNGARAAYGARTCN CCNCARAARCARTGGMGNGARGCNACNCCNCCNMGNYTNGTNAAR---CCNTCNCAR--- ------------AARCARMGNCARTCNTCNTCNACNGAYAAYAAR---MGNAARCCNYTN ---------------------MGNGGNTCNMGNTCNCCNCCNCARMGNMGNMGNGGNAAY TCNMGNTCNCCNCCNMGNMGNTCNCCNAARCARGARACNTCNGTN--------------- ------------CCNMGNMGNCARMGNAARGAYACNGAYTCNTCN---GAYCARGARGCN ATHAARMGNGAYMGNMGNMGNMGNGAYAAYYTNAGYCCNCCNMGNAARMGN--------- CCNGCNMGNTCNCCNTCNCCNMGNMGNGARMGNGAYGGNGGNAAYMGN---------AGY YTNCARMGNCARTCNACNCCNCCNGCNAAYGARAARTCNMGNGAYAARTCNGAYMGNAAR CCN------------CARCCNGTNMGNAAYGARAARCARGCNTCNTCNTCNGAYAGYAGY AGYGGNAGYAGYTCNGGNGARGARGARAARGCNCCNAAR--------------------- ------------------------------------AGYAARCCNAARGCNGCNYTNAAR CCNCCNGTNGAYAGYAAYMGNTCNGGN---------MGNMGNGCNTCNCCNGCNGCNCCN TCNAARMGNTCNYTNAGYCARTCNCCNCCNCCNCARGCNTCNAARTCNTCNMGNMGNGAR GCNAARGAYGTNMGNGAYGARGARAAR--------------------------------- ---------YTNMGNAAYCARTCNCCNAGYAARGGNGGNAAYGARMGNGAYGGNACNCCN ACNMGNAAYGGNAARGTNTCNGCN---------------------------------TCN GCNAARCCNCCNAAR------AARGAYAARCCNGCNCARTCNGCNAGYAAYAGYGARTCN GARTCNAAYTCNGAYGAY---GGNTCNAARAARAARAARAARAARAARGARAARAARCAY AARAARCAYAARAARCAYAARAARCAYAARCAYAARAARGARGTNGGNGTNCCN---GAR AARGGNGARGAYYTNGARATGMGNYTNMGNGARAARGCNYTNATGTCNYTN------YTN CAYMGN---------AARAARCARACNTCNCARCCNCCNGAYAGYGGNAGYAGYAGYGAR GARGARACN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARAGYGAYAAR GARAAYACNGAYGCNYTNAARGARAGYAARGARGARGAYGARAARYTNCARGARTCNAAR CCNTCNGAYAGYGARGAYTAYGARTGGYTNAGYYTNGARGAYGTNAARGTNACNTTYYTN CCNYTNTCNTGYGTNCCNGARYTNTCNAARAARAGYAARTAYCARAARTTYTTYAAYGCN GTNTTYTTYTCNAAYAGYACNGTNCAYYTNTTYAARCCNGARGTNTCNTCNATGTTYGCN GAYAARTGYGCNGTNGTNYTNGARACNGCNYTNTTYATGYTNCAYATHAARAARAAYGAR GTNCARGARTTYTTYAARMGNATHTCNGGNATGGCNGTNAGYGCNGGNTGYAARCCNGTN GARGARGTNGAYGAYYTNCARGAYTCNTAYGCNGCNTTYTAYTAYGARMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNAARGARGARAGYAARAARGTNAARGARGCNGARTCNGCNGGNAARGCNTTY GCNACNYTNGAYGTNAAYGGNGAYGGNAARGTNGAYTAYCCNGARYTNATGAARCAYAAR GARTTYGAYATHGAYTCNGAYGGNACNGTNAGYGAYGARGARGCNAARGARTAYYTNGAR GARTAYGARGARGTNGAYYTNGCNACNTTYACNGARAARATHTGGCCNAAYATHAARGAR ATHTAYAARCARCCNAARGGNGAYAGYGARGARCCNGCNCCNGARGARAARGAYGGNGAR GTNGCNCCNCCNGARGAYATHCCNGAYGTNGTNGARGGNGGNGCNCCN---GAYMGNGTN GARGARGARGAYGAY--------------------------------------------- ---------------GARGAYAARGARCCNGAYTAYAAYGAYGARACNAARGCNYTNATH GCNGCNGCNGAYGTNGARMGNAAYAARTTYAAYGARGCNGARMGNAARYTNCARGAYAAY GARMGNGARATHAGYGAYATHAARAARTAYYTNGARYTNGAYTTYGGNCCNAAYCARGAR TTYTCNGCNYTNAARGGNCARTGYTTYGARTAYACNGAYMGNGARTAYACNTAYMGNYTN TGYCCNTTYGAYAARAGYACNCARAARAGYAARAAYGGNGGNATGGARACNTCNYTNGGN AAYTGGGGNAARTGGCAYGGNCCNGAYGARGAYAARTAYGAYACNATGAARTAYGARAAY GGNCARGGNTGYTGGAAYGGNCCNGCNMGNTCNACNCAYGTNAAYYTNCAYTGYGGNTCN ATHAAYGCNGTNACNAGYGCNTCNGARCCNAGYMGNTGYGARTAYCARTTYGARTTYACN ACNCCNGCNMGNTGYGAYTCNCCNAAYTCNGARGAYATGAARGAYGTNCAYGAYGARYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TTYCCNGGNTTYAAYGTNYTNGTNAARYTNGARTTYMGNGCNGARTTY TCNAAYGARYTNACNGTNTTYACNTCNGTNGARAAYAARGGNGAYGCNAARATHTGYCAR GCNMGNGTNAGYGARATHTCNGCNGARGTNGCNGAYAAYGCNCARGTNCAYYTNATHCAR GARGGNACNGARACNTCNYTNTGYMGNAAYTAYYTNACNYTNCAYAAYYTNCARAGYYTN AARACNCAYYTNACNATHMGNGTNACNGTNACNTGYATHYTNCAYGAYAAYACNAARGAR GARMGNTCNCARAARYTNGAYYTNCARCARCCNYTNGTNGCNMGNYTNTGYYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNAARCARGARGAYGAR TCNTTYATHAARATGTTY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNACNCCNACNCARAAYYTNCAYGAYMGNACN ATHTTYAAYTTYTCNCARCCNCCNGCNGCNATHTCNATGACNCARGCNGAYCARYTNGCN GGNCARCARTTYATHACNATHCCNGTNCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GAYGAYATGTAYMGNTCNCCNYTNGAYTTYGCNAARGAYATHGGNAAYGCNATHACN GGNYTNGCNGAYTAYTTYGAYGCNGAYYTNYTNGARAAYGARGARGCNTTYAARGCNGAY YTNTAYCCNYTNGAYCCNGARGAYATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYAGYCCNAAYATGAGYMGNYTNATHTAYYTNGAYACNCCN GTNGGNGGNGGNCAYCAYCARTGYTCNMGNYTNGTNGCNATHGAYTGGGCNACNMGNAAR AGYMGNGTNGTNGTNGAYATHGTNAARCAYGCNMGNGCNTCNTCNTTYCARGGNATHTTY ACNGCNGCNGTNCCNMGNAAYGTNTGGTTYGARGAYAAYATHCAYYTNGCNYTNACNACN GCNTGGMGNAGYATGACNACNGTNGTNATHATHGAYACNGAYAGYGGNACNGTNAARMGN YTNCCNAARGAYGARAAYCARAARAGYGTNTCNYTNYTNGGNGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNGGNAAYTCNYTNMGNMGNGTNGGN ACNACNMGNCARYTNGTNGTNATGATHACNGAYGGNGTNTCNTCNTCNATGMGNYTNCAR YTNGGNGCNYTNTTYGAYCAYGTNATHCARGTNAAYATHYTNGAYAGYTCNGAYACNTGY AAYYTNAAYYTNYTNGGNMGNCCNGAYYTNAGYTGYACNTTYACNAARYTNCAYTGYTGG MGNYTNACNCARTTYAGYAARTGYGTNTTYATGGAYGCNGAYACNYTNGTNATHAARAAY GTNGAYGAYYTNTTYGARMGNGARGARYTNGCNGCNGCNCCNGAYGCNGGNTGGCCNGAY TGYTTYAAYTCNGGNGTNTTYGTNTAYAARCCNTCNGAYGCNACNTAYACNAGYYTNYTN CARYTNGCNGTNTCNCAYGGNTCNTTYGAYGGNGGNGAYCARGGNYTNYTNAAYYTNTAY TTYAGYACNTGGGCNACNGCNGAYATHGGNAARCAYYTNCCNTTYACNTAYAAYGTNGTN GCNCARGCNTTYTAYAGYTAYYTNCCNGCNTTYAARCARTTYGARGAYCARATHAARATH GTNCAYTTYATHGGNGCNGTNAARCCNTGGCAYCAYCCNTAYAAYATGAAYACNGGNACN GTNAGYGTNYTNCARGAYACNGGNCAYAAYCARAARTTYYTNCARATHTGGTGGGAYYTN TTYATGGAYAARGTNCAYCARCAYYTNGAYGCNGARYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GAYGCNACNAGYGARGAYATGAAYAGYGCNGGNAARMGNGTNACNGAYTCNGCNTTYGAR TTYYTNAAYACNTAYYTNTCNGAYGARGARGGN------GARMGNGTNGAYAGYCCNCCN GTNTCNCCNATGATHGCNMGN---GARGCNGAYTCNCARGCNYTNAARYTNAAYTCNTCN YTNGTNGAYAAYGARYTNCCNTCNGTNAGYTGYGAYYTNGCNGAYYTNAAYATHACNTCN AAYGAYTTYGARCARYTNYTNYTNCARAGYYTNGGNGAYATGCCNGTNTCNYTNGAYGGN YTNTCNATGGAYTGYGAYGARTCNYTNCARAAYGCNACNGCNCARCCNYTNTGYGARYTN ACNAGYATGATHGARGAYACNAARTGGCCNMGNGAYTTYGAYATHTCNTTYCCNATGGAY GCNAAYYTNGTNTCNTTYTTYCARAGYGCNGCNGARTCNGARGCNAAYYTNAARGGNGGN GTNACNCCNCCNTTYTCNGGNGGNAGYACNCCNCARAGYCARTCNMGNGCNGCNTCNCCN GCNTGGAGYGARAGYAGYGGNAAYACNAGYGCNAGYAGYATHTCNGGNCCNTCNTCNGGN ACN---------YTNAAYAAYGGNAAYYTNATHCCNMGNCAYAARMGNCCNTCNCAYMGN MGNGCNGARGTNAARMGNMGNGAYAARATHAARACNTGYYTNGAYGAYATHAARGARCAY ATHCCNTCNYTNCARGARAARGGNAARYTNAGYGARTCNACNATHYTNNNNAARAGY--- ------------------------------------------------------------ ------------------------------------TCNGTNCARGARACNYTNCCNGCN AGYGGNYTNAARGAYGARGCNAARGTNCAYCCNMGNYTNGAYGAYYTNTAYACNAAYTGG GTNGCNGARCARAGYAARATHTCNACNAARCAYCAYATHTTYACNTTYATHACNTCNAGY ATGTTYGARTCNTTYAARGAYATHGTNGGNCCNGCNAGYTCNAGYGAYTCNYTNGTNTAY AARATHAARGARTGGCARACNAARTAYYTNAGYYTNCCNGTNYTNMGNAARCARATHYTN AGYGGNATGYTNAARYTNACNAARAARAGYAAYATGGTNACNYTNCCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARGGNGTNMGNYTNMGNCCNAARTCNTCNTCNMGN AAYAARTCNCCNTCNCCNTGYTCNGAYAARGAYTCNGCNATHGGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARAAYACNAGYACNAARGARGTNTGGTTYGARGTNCAY AARYTNCCNGTNGARAAYTGGATHAARGARYTNGARACNYTNCARGCNGCNATHACNAAR CARAARGAYGARAAYGARAARGCNYTNACNGAYTTYGTNGCNCARGGNGGNGARTCNGAR CARGAYGCNYTNCCNAARGGNCARCCNCCNAARACNGAYGARGTNGTNGCNAGYGTN--- ---GAYTCNGTNATHGARAARGTNGGNACNAARTTYAGYCAYCCNTCNYTNACNTTYAAR GCNAARCCNCCNACNAAYMGNTTYCCNACNGCNAAYTCNTCNTCNAGYATHGCNTCNGCN GTNTCNAARGTNGAYCARGGNGAYGTNYTNGGNACNGGNACNAAYCAYGTNYTNAGYGCN GCNCAYYTNGARTCNMGNGARGCNATGTTYAAYCAYMGNTAYGAYGAYYTNYTNAARTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNCCNGCNTAYGCNACNCCNCCNGCNTGYYTN CAYMGNGTNGGNYTNGARTCNAGYTCNACNGGNTCNTCNTTYCCNGCNGAYTTYACNAAR CCNGTNCCNYTNGCNGTNGTNTCNCCNGAYGGNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATHAARATHTAYAARACN TCNATHYTNATHTTYAARAAYMGNGAYMGNTAYGTNACNGGNGARTAYMGNTTY---MGN CAYGGNTAYTGYAARTCNAAYCCNMGNAARATGATHMGNGTNTGGGCNGARAARGARATG MGNAAYYTNTCNMGNYTNCAYAARGCNCARATHCCNTGYCCNGARCCNATHYTNYTNAAR AGYAAYGTNYTNYTNATGACNTTYATHGGNGARGAYYTNGCNGCNCCNYTNYTNAARGAY GTNGAYYTNYTNGARTCNAARGCNMGNGARYTNTAYYTNGAYGTNATHYTNATGGTNMGN MGNATHTAYCAYGAYTGYMGNYTNATHCAYGGNGAYYTNAGYGARTTYAAYATGYTNTAY TTYCAYGGNCARGTNTAYATHATHGAYGTNTCNCARTCNGTNGARCAYGAYCAYCCNCAY GCNATGGARTTYYTNMGNAARGAYYTNACNAAYGTNACNGARTAYTTYMGNAARAARAAY GTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TCNGCNGAYGTNAGYCARGTNTAYGGNCCNACNGGNTCNGAYTAY YTNTTYATHACNYTNGGNGGNGARTTYCAYTGYGTNTCNYTNAAYACNGGNTGYGGNGTN YTNGTNYTNGAYAAYCCNGCNMGNCCNMGNGTNCCNTCNTTYMGNGGNYTNGTNATHGAY GAYAARCCNTTYGGNYTNTCNMGNACNCARAARGTNTCNTTYGTNGGNAAYATGGGNTCN YTNAAYATHGTNTTYTAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MGNAAYATHYTN GARGCNYTNGTNAARAARGCNAARCCNYTNAAYGCNYTNGARAARYTNTCNMGNAAYACN MGNYTNYTNTAYATHCAYAGYTAYCARTCNYTNGTNTGGAAYACNATGGTNTCNAARMGN YTNAARCAYTTYGGNCAYCAYATHGTNCCNGGNGAYYTNGTNATGGARAARAARGARMGN ACNAARGGN---------CARGAYGCNCCNAGYCCNACNGTNGTNACNGARGCNAAYATH GCNGAYTAYACNYTNACNGAYGTNGTNYTNCCNYTNCCNGGNTAYGAYGTNTGYTAYCCN CARAAYCARGTNGCNGARTGGTAYMGNGARYTNYTNACNGCNGAYGGNYTNGAYATHGAY AAYATGAARMGNCCNCARAARGAYTAYTCNYTNTCNGGNGCNTAYMGNCAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARATGGCNGAYGARYTNCCNYTNTTYCCNAAR GCNTCNTCNATGTAYYTNCAYAGYGGNAAYATGATHAAYTGGAAYAGYYTNAARMGNAAR ACNAAYYTNTCNTCNTCNGAYGARYTNTAYGARGTNATHACNGCNACNYTNGGNTCNTAY YTNACNGCNGCNGAYAARACNGARYTNCARTAYGTNACNGARGTNCAYAARACNAARGCN GARAAYGTNGARGTNATHGAYGARAAYGARMGNGGNGAYATHAARGTNACNGTNAARATH TTYATHTGYGAYTCNCARTCNACNAGYGTNGTNGGNGAYGCNGTNAGYMGNGTNYTNAAY GARYTNGGNACNAAYTTYATHGARACNYTNYTNYTNGCNATHTGYCCNAAYGGNGGNGAY GAYCARGAYACNGARGARGTNGTNAGYYTNTCNACNATHCARAARTAYTGGCARGCNATG GARGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNGARGCNCARCARMGNCARTAYGTNGTNCARYTNCARATHGARGARATHACN MGNAARYTNMGNACNGGNGARYTNGGNATHCCNTCNAAYCCNGARCARMGNTCNCCNTCN CCNGARCCNATHTAYAAYAAYGARGGNAARMGNYTNAAYACNMGNGARTAYMGNACNMGN AARAARYTNGARGARGARMGNCAYAARYTNATHCARGARGCNYTNAARYTNAAYACNGAY TTYAARCCNCCNAGYGAYTAYAARCCNCCNATHGTNMGNGTNAAYGAYAARGTNATGATH CCNCARGARGARCAYCCNGAYATHAAYTTYGTNGGNYTNYTNATHGGNCCNMGNGGNAAY ACNYTNAARACNYTNGARAARGAYACNGGNGCNAARATHATHATHMGNGGNAARGGNTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TCNCCNATHGTNTCNTCNTCNTAYTGYATHATGAGYGTNTCNTCNTCN TCNYTNATGYTNTCNTCNGCNGCNACNGCNGCNCCNCCNGTNTCNTCNAARGTNGTNYTN MGNAARGAYAARAAYMGNMGNGTNYTNGAYMGNCCNAAYAGYATHGCNTTYTCNTCNTAY CCNATHTGYGAYYTNATHCCNAARGCNAAYGARAAYCARAAYGGNGCNATHCCNAGYCAY GAYGAYACNAGYAGYGCNGGNGCNCCNGGNYTNGCNMGNMGNTCNMGNTCNTCNYTNAGY CCNGAYGTNCCNTAYCAYMGNGGNMGNACNTCNTGGAGYTGYTAYTCNGARMGNGARGTN TAYMGNCARATHACNGCNGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY CCNYTNACNATGGARCARYTNYTNGARCARCARTGGGARCAYGGNGCNCARTTYYTNATG GARCARAGYGAYCAYTTYGAYATHTCNTCNYTNYTNAAYTGYYTNCAYMGNYTNAARTCN GARAAYCARCARYTNGARGAYCARGTNCARGAYYTNACNTCNMGNMGNAGYCAYYTNATG ACNGTNAAYGCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNAAYGCNYTNTGGAARGARATGGCNGCNAARCARGTNACN GGNCAYATGAGYCARAGYATGMGNTCNMGNTTYYTNGARAGYATHATGCCNAAYYTNGAY MGNTAYGAYYTNCCNCCNGAYMGNAARGAYAARYTNAARMGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR ATHYTNMGNGARGGNGGNAARAAYAARYTNATHATHGGNGTNAGYGTNGGNGGNGCNGTN YTNYTNATHATHATHGCNGTNYTNATHGTNMGNAARGTNATGMGNGGNMGNMGNMGNCAR TCNTCNMGNMGNTGGGARAAYATGGAYATHAAYTAYGGNAARMGNTAYTAYAAYAARGCN CCNGAYAARGAYGAY--------------------------------------------- ---------------------GARCCNAGYGGNACNTCNCCNGGNATHYTNCCNGAYTTY YTNTCNGAYGGNCCNYTNYTNAGY------------GGNAARCAYGCNGTNCCNGAYGAY MGNGGNAARACN---------GAYGARGAYYTNYTNAGYCARATHCAYATHYTNCARGAR GARAAYAGYMGNYTNCAYAARGAYYTNACNMGNATGAARCAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNGTNYTNACNGGNCARACNAGYGAYAAY ATHTCNTCNYTNGTNATGCAYGARGTNMGNGARYTNGARACNTGGATHYTNMGNYTNYTN AGYTCNCCNGTNCCNGTNCCNGGNAARACNMGNGTNGARGTNCAYATHYTNCCNAARGAY YTNCARCCNCCNYTNYTNTTYGCNYTNCCNGAYAAYACNMGNTTYAGYYTNGTNGAYTTY CCNYTNCAYYTNCCNYTNGARYTNYTNGGNGTNGARAARTGYYTNACNGCNYTNACNGCN ATHATGYTNGARCAYAARGTNATHYTNCARTCNMGNGAYTAYAAYTCNYTNTCNATGTCN GTNATGGCNTTYGTNTCNATGYTNTAYCCNYTNGARTAYATGTTYCCNGTNATHCCNYTN YTNCCNACNTGYATGGCNTCNGCNGARCARYTNYTNATGGCNCCNACNCCNTAYYTNATH GGNGTNCCNGCNAGYTTYTTYGGNTAYAARAARGAYTTYYTNYTNCCNGAYGAYGTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYAARTGGTAYMGNGTNAARGCNGGNYTNTTYYTNGCN TCNGTNACNGGNTGYTCNATHYTNGCNGGNTTYGGNYTNACNGTNGGNATGGCNAARAAR AGYGAYCCNAGYAAYTTYGCNAARGGNYTNGTNGGNTCNMGNGARYTNCCNGARAGYGGN GTNGCNYTNGCNACNMGNGCNYTNACNMGNGCNTCNYTNTAYTCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARGARGARTGYGARTAYTAYMGNCARMGNTAYAAYAGYYTNMGN ATHATHTAYGARGARATHGAYGGNMGNYTNACNATGTAYAARAAYMGNTGYYTNGGNGTN GAYACNGTNGTNYTNACNYTNCARGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GGNATHYTNTGYCAY AGYTGY---------CARTAYGTNAARTGYAARGAYAARTAY------------GAYTAY GAYCCNAAYAAYYTNGGNGAYTGYGGNGAYGGNCARTAYTGYGTNAARTAYAARACNATH GCNTGGATHCAYGAYTCNGGNGARATHACNGGNTCNYTNMGNGARTCNCAYGTNGTNACN MGNACNTGYGARCCNAARAARGGNMGNAARGARGGNTGYACNGGNTGGCARAAYAAYGGN GGNATHACNYTNAARTGYTGGTGYGGNTCNGAYGGNTGYAAYGGNGGNMGNTCNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TTYTTYATHATHGTNGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARAAYGARAARCARTCNGCNAARGAYATHYTNAAYTCNYTNCARGGN MGNCCNAARAARAGYAARTCNGCNGGNAARAARACNATHCCNCCNYTNATGYTNGAYTCN YTNGGNMGNCCNATGATHCCNATGATGYTNGGNGARATHACNYTNCAYAGYATGGGNGAR ATHGTNACNGAYMGNACNGGNTTYCAYTGYGCNGARGCNATHTTYCCNGCNGGNTAYTGY ATHACNMGNGTNTAYGTNAGYYTNCAYAARCARGAYGCNAARTGYYTNTAYACNTGYAAR ATHTCNGAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGAAYTTYAAYATHGARYTNGCNYTNGCNTCNGGNGGNMGNATHGGN AARATHACNCCNATHGCNCAYGGNMGNACNGTNTCNYTNCCNACNCCNATGTGYACNYTN TTYACNAARGGNGGNAGYNNNCCNTAYYTNAGYYTNAGYATGYTNGAYAARATHAARMGN GTNCCNCARYTNGCNACNATGAGYGTNAAYTCNTTYGTNGAYCAYTTYGAYAGYATHAAR GARAAYGGNAARGGNYTNGCNAGYTTYACNTCNATGAARGAYAARYTNGTNTTYTCNACN YTNCAYGAYGCNAGYYTNCCNGTNCARTCNGGNAARAAYGAYMGNTCNGGNGTNGCNGTN TGGGGNAARGGNGGNAARACNAARYTNGAYCCNAGYCARTAYATGAARATHCARGARGCN YTNAARGCNGAYTGGATHYTNGCNYTNAAYGAYGGNGAYACNGAYCARGARAGYGGNGAR AARMGNTCNGGNAARGCNGTNGAYMGNACNYTNGAYTTYYTNGAYGARATGGTNGCNCAR TGGAARAARAGYGARGARYTNAARAAYTCNAGYYTNATHGGNGTNATHGTNGGNGGNTAY AGYGGNMGNCARMGNGARMGNAGYGCNAARGARACNTCNGCNMGNCCNGTNCAYGGNTTY ATGYTNGGNGGNTTYCARAARGGNAAYACNCARGARAAYATHYTNGAYAAYGARTCNTTY ACNAARATHYTNACNGARACNYTNACNCAYYTNCCNGARAAYAARCCNMGNATHATGGAR AAYCCNTGGTCNCCNYTNCARGTNGTNAARGCNTTYMGNYTNGGNGTNGAYGTNTTYTCN AGYGCNTAYCCNCAYACNYTNGCNGARAARGGNATGGTNATGATGGARGAYTTYAGYYTN CCNCCNCCNTCNCARCCNGCNGTNYTNGARAARGGNGARTCNGGNGCNGAYTCNATH--- ---GGNCAYGTNATGGAYATHAARGARAARMGNTTYTTYGAYGAYTTYMGNCCNGTNYTN GAYGGNTGYCCNTGYTAYACNTGYGCNACNTTYACNMGNTCNTAYATHCAYCAYYTNYTN AAYACNTCNGARYTNYTNGCNAAYGTNYTNYTNACNATHCAYAAYTTYGARMGNTAYTTY GARTTYTTYCAYTCNYTNMGNGAYGCNGCNCARACNGAYMGNYTNGAYGARYTNGARAAR AARYTNTCNAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATGAARGTNAAYYTNGCNGGNCCNAARTCNAGYAAR CCNGAYMGNTCNYTNGAYGTNGTNAARGGNTCNATGGTNGARGAYYTNGTNGGNATGYTN CARTCNTTYAARGARAGYGTNACNAAYATHTAYAARCAYGGNMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MGNAGYYTN ATHGARCARGAYMGNYTNGARCARYTNGCNAARGARMGNCARAARGCNATHGARGTNATH ACNAARGCNCARTCNGARAGYCARGARTTYTCNAARAARACNGARGARAARYTNAARMGN TCNATGGARACNMGNMGNGARAAYMGNGARGCNCARATHMGNGCNYTNCARGARMGNYTN MGNGARCAYTCNGTNAARGTNCAYGAYGTNCARAARACNGGNATGGARATGGTNAARGAR TTYGARGCNAARGCNGARCARAARYTNACNCARAARATGGGNACNTAYGARGARAAYMGN AARAAYCARYTNTGYAAYATGYTNTCNAARYTNCARGARCAYGCNAGYCAYATHAAYGAR GTNTGYGTNGCNAGYGARAAYMGNGGNGCNAAYACNGAYGARYTNCARGARCARYTNGTN CARAARATGGARAAYGCNYTNAARAAYMGNGARGARCARYTNMGNGTNATHCARGAYMGN YTNGCNGARCAYGARAAYMGNATHAARGARGTNCARMGNAARAARGGNATGGTNTCNTCN GGNGARCCNTCNTGYTAYAAYTGYCAYYTNTGYTCNGCNAARYTNAGYACNGARTTYTTY YTNMGNCAYCAYYTNGCNAARCAYAARGGNTTYMGNCAYATGTCNACNYTNTCNACNYTN GAYGGNGTNYTNATHTGYTCNCAYTGYAGYTAYATHGCNAGYAGYAAYYTNGAYYTNGCN AAYCAYGTNTCNYTNCAYGTNACNGAYMGNMGNTAYAARTGYTCNYTNTGYGAYTTYGAR AGYCAYMGNAARAARTCNATHGAYTTYCAYATHYTNAARCARCAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNAARYTNCCNYTNYTNTCNTAY GAYGAYYTNATHGCNGTNYTNCAYTTYYTNTAYACNAAYMGNYTNCCNTCNGAYTGYCCN YTNGAYAARYTNGCNMGNYTNTGYAAYAAYGCNTCNTCNTTYGARGTNCCNGARYTNAAR ACNGCNGCNATGTAYAARATGGTNGARGGNYTNACNTGYGCNAAYGTNGTNTCNGTNTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CARCCNATHCCNACNTCNTGYGCNAAYGCNAGYGTNCCNTCN GCNATHGTNAAYAAYATHGGNGTNGGNACNACNGCNCCNTGYGTNGAYGTNGARTGYAAR GTNCAYCAYGAYGARAAYTGYGAYAGYGTNGAYGAYAGYTGYTCNGARMGNAGYTCNAGY ACNTCNTCNAAYCARAARGARGGNAARTAYTGYGAYTGYTGYTAYTGYGARTTYTTYGGN CAYAAYAAYCCNCARGGNGCNAARACNAGYCCNAAYTAYTTYGARATGAARGAYMGNYTN MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGGGGNGCNATGMGNCCN TCNMGNACNCARGCNATGCCNAARCAYTCNYTNTTYGGNACNGCNYTNGARCAYGTNGAY MGNGARGGNYTNAARGAYATHGARGGNMGNTAYATHCCNGARGGNYTNGTNAARGARAAR CCNGAYMGNTAYCCNYTNCCNCCNCAYATHATGGARGGNATHCCNGGNMGNGAYMGNYTN GARACNTCNMGNAARGARYTNGCNGCNCARMGNAAYGCNTTYTCNCARGCNGAYCARAAR YTNAARTCNAARTCNGCNAARGTNTTYGCNTTYAARCCNTCNGARCAR---------CAR AAYCARGGNAGYYTNCCNTCNAAYMGNCCNACNTGGYTNTCNGARAARGAYYTNGARCAY TCNAARGAYATHAAYATHYTNGGNYTNTCNCARCAYGGNAGYTAYAAYMGNGAYAARTAY GGNAARAARCCNCARGTNCAYAAYTAYAGYYTNATHGGNGAYATHYTNGCNCARAARATG GAYTTYAAYTCNGCNMGNACNAGYGARGAYAARAGYAARGTNGGNATHGAYAGYAGYAAR ACNAAYGTNACNTGGGGNCCNGGNMGNCAYYTNCCNTAYGAYATGATGGARCARGARAAR AAYTCNAARAARAARACNGAYTAYAARAGYGTNATHGAYYTNCCNCCNAAYATHMGNCAY CARTTYGGNAGYMGNGTNTGYGAYACNYTNYTNTCNGAYCARAAYYTNGTNTCNYTNGCN YTNGARMGNCARAARTCNAARATGGGNCCNYTNMGNCCNTCNAARAARGARAAYGTNCAR GGNYTNCCNGTNAAYYTNAAYAAYAAYTAYGARAGYYTNGGNCAYACNACNMGNTAYAAY GTNTGYCCNGGNGTNAGYTCNGGNCAYACNATHAGYMGNACNAARGAYGARTTYAAYGAY GARGTNCAYYTNAARMGNGTNCCNAAYCCNGAYGARTAYMGNTAYCARMGNGAYGARYTN AGYNNNATHTGGGTNGARCARGAYGTNYTNMGNAARMGNATGGARAAYAARTGGACNTCN TAYTTYGARAARATGCCNAARGCNGCNAARMGNCCNCCNCCNTCNAARCCNAARCCNAAR ATHCARMGNAARTCNAARCCNAARCCNGARGARGTN---CCN---GTNGAYAAYGARATG GAYATHGTNTTYGTNACNCCNCCNYTNACNCCNCCNCCNCCNCCNCARGARTTYGTNGAR YTNCCNAARGCNTTYGARAARGAYGAYGCNTTYTGGAGYTTYTAYGAYCAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TCNCARTGYMGNGARACNGTNTGYATGTCNGGNAAYTGYAGYYTNTTYTAYACNCAR MGNTTYTGYYTNAARTGYGCNTTYGAYCARYTNTCNGARTTYCCNCCNGARYTNCAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MGNGTNYTNGAYGCNGARGARGAYGTNAGYAARACNATGTAYAGYAARGARGAY ACNGTNATHCARGARGTNCAYTAYGGNAARACNYTNTCNAAYGGNGTNAGYAAYCCNGCN YTNGTNAAYCCNACNTAYGARMGNGARCCNCCNACNTTYYTNGAYACNCARCCNGTNCAR TGGGGNCCNGAYATHCAYAARCCNACNTCNGCNGAYCAYYTNAAYCCNYTNACNTCNTCN MGNMGNATHCARGAYMGNGARYTNCARGARATGAGYGAYGARGGNATGTGYATGAGYATG CAYCARCCNYTNGCNTCNYTNYTNGTNTGYGGNATHAARATGCAYGARGGNMGNACNTGG TAYACNGCNCAYMGNGGNMGNYTNTGGATHGCNGCNACNGCNAARACNCCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGAYCAYACNMGNCARCCNGTNACNCARGARYTNYTNATGYTNGTNGAYGARAARGGN TGGMGNGARGTNTTYTTYATGAAYAARYTNCARYTNCARGTNCARATGMGNMGNCAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CARACNTAYCARGCNCARACNAAYAAY YTNCCNGGNGCNTTYGARGAYGGNCAYGTNTCNTAYGGNCCNTAYCAYAGYYTNGARGTN GTNGARGTNGAYCCNGGNAARCAYGTNGARATHCAYATHGGNTAYATHGARACNGTNGTN GTNATHMGNCARATHGGNMGNTAYTTYACNTTYTCNATHAARATGCCNGARGARYTNATH AAYTCNAGYMGNAGYGGNGAYYTNCARYTNTGYGCNMGNGGNTGYCCNAGYTCNGARYTN ATHAAYTAYAARGARTAYYTNGCNAAYMGNAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGCCNACNTTYAARATHGARACNAAYYTNCARAARGAYCARATHCCN GARAARTTYYTNCARGARGCNACNAAYYTNATHTCNTCNGARYTNGGNAARCCNGGNACN TAYGTNTGYATHCARGTNTGYCCNGAYCARGTNATGAGYTTYGGNGGNACNACNGAYCCN TGYGCNAAYATHACNYTNAGYTGYATHGGNATHGTNGGNCCNGAYAARAAYAARAARYTN GCNCCNYTNYTNTCNAAYTTYATHGARGARCARYTNGGNATHAARCARGAYMGNTTYTAY ATHAAYATHTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------MGNAAYTAYGTNAAYGARAGYATGAARGTNGARTGYCCNGTNGCN CARGARGCNGGNAGYATGMGNMGNTTYGTNGGNTTYGARTCNGCNMGNACNGCNATHGGN CAYGAYMGNATHGGNAARGTNCAYGTNGTNCARGTNAGYGGNTGGTCNGARCAYATHGGN ATHAAYATHTTYGARTTYAGYGAYYTNYTNGTNAGYYTNGGNATHGTNAAYGCNATHAAY YTNGAYGGNGGNGGNTCNTCNACNTCNATHATHAAYGAYACNYTNGCNGGNTTYACNAGY AAYAARTGYGAYGARATHTAYAGYTGYGARMGNGAYGTNTCNACNGTNATHTGYGTNCAY TAYCCNGARTGYTCNCCNCCNAAYTGYTCNAAYCAYGGNGTNTGYAGYAAYGGNAARTGY CARTGYMGNGAYCCNTGGATGGGNGAYGARTGY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ACNGTNTCNTTYYTNYTNGARAGYGTNCCN GGNYTNAARGARAARYTNGARAARGGNATHGARGTNATHGARTTYGGNTGYGGNMGNGCN CAYGTNYTNTCNYTNYTNGCNTCNAARTTYCCNAAYAGYACNTTYACNGCNTCNGARGTN YTNCCNCAYYTNGTNGARACNATHAARACNAARYTNGGNCAYYTNCCNAAYATGAARTTY GARGTNGTNGAYATHTGYTCNYTNCCNCAYACNGTNGAYAARAARTAYGAYTGGGCNYTN TCNATHGAYGTNATHCAYGAYYTNCCNCAYCCNGGNGARGCNYTNAARGGNATHMGNMGN ---YTNGTNGCNYTNGAYGGNGTNTTYACNTTYYTNGAYATGGCNGGNACNGGNAGYCAY GARAARGAYGTNGGNGAYCAYCARGCNGCNAGYYTNTAYTCNYTNAGYACNTTYYTNTGY YTNCCNGARAGYTTYCARAGYGARGAYAGYGARGGNCAYGGNGCNAAYTGGGCNAARGAR ACNGCNYTNGARTTYGCNMGNYTNGCNGGNTTYGAYACNTCNGTNATHCCNATGGAYGGN AARATGGCNYTNTAYYTNGCNAARGAYCCNGARAAYCCNCCNGARTAYACNGARMGNTCN AAYGTNGCNACNGGNGCNTCNGAYYTNCCNGAYTAYAAYACNGCNACNGAYCAYGARCCN CCNCCNCCNTCNTAYGAYTCNYTNTAYGGNMGNYTNAARTCNGCNAARGCNGARTCNGAY GGNACNYTNAGYTTYTTYAARACNTTYYTNGTNATHATHTTYTCNACNGTNGGNTTYACN ATHYTNYTNGGNYTNATHATGGCNGTNCCNGTNTCNATGATHGTNATGGGNTCNATHCAY YTNGAYGAYTGYGAYGCNGARMGNATGATHCCNATHTAYYTNATHGTNGCNGGNACNTTY GGNTGYGCNAARAAYYTNTTYAGYYTNATHCARMGNTGYMGNAARACNGARGARGARMGN CARGARGAYCARAARAARGTNAAYCCNGTNTCNAGYATHGTNGAYTGYTTYYTNTTYGCN TGGTTYATHGCNGGNTGYGTNTTYATHTAYMGNACNAARGAYTTY------CARTCNAGY GAYAARAGYYTNCCNGARTAYTGYGAYTAYGAYYTNTAYTGGTTYGCNTTYTGGATGACN ACNGCNATGTAYATHATHGCNGCNGCNAGYTGYYTNTGYGCNTGYGTNTCNGGNTGYTTY GTNGCNGTNTGYGCNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNAAYAAYGTNTTYYTN MGNTAYGARMGNTTYGARMGNTAYMGNACNGGNCARTCNGGNCARGCNACNACNCCNGTN TCNGARGTNCCNCCNAAYGAYTCNYTNCCNCCNGCNTAYGAYCARYTNCCNGCNGCNAGY AAYCCNAARGTNGGNAAYYTNATHGAYYTNAGYGAYGAYCCNGTNCCNAAY------TCN ATHAAYTCNCARYTNGCNGGNYTNAGYYTNAAYTCNACNACNGCNACNAAYGCNGCNCCN CCN---CCNCARMGNGGNGAYGAYGAYTTYGAYATGTTYGCNCARTCNMGNCARTCNTTY GAYCARAGYMGNCARGCNGTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNAAYAAYGTNYTNAAYTCNYTNATGTAYGGNTGYGCNMGNYTNGGN GTNGAYYTNAGYGTNGCNACNCCNCCNGGNTAYGARCCNGAYGTNGAYATHATGTTYGAY GCNATGAARATHGCNGGNAARACNGGNGCNTCNTTYCARATGGGNAAYAAYCCNYTNGAR TCNGTNTAYMGNGCNGAYGCNATHATHGCNGAYGCNTGGYTNACNAARGGNCARACNGAR GARGGNMGNGARAARYTNGTNACNGAYTTYCARGGNTTYCARGTNAAYMGNAARATGYTN AARGARGCNGGNGGNAGYTGGGTNTTYYTNCAYTGYYTNCCNMGNAARCCNGARGARGTN CCNGAYGAYGTNTTYTAYGGNGARGARTCNYTNGTNTGGCARCARACNGARAAYTGYATG TGGACNGCNATGTCNGTNATGYTNCAYGTNYTNGARCCNTAYACNCCNACNACNCCNATG CCNAARTAYGTNMGNGGN------------------------------------------ ------------------------------------------------------------ ---CARACN------CARAAYACNGCNCARYTNMGNTCNATGYTN--------------- ------------------------------------------YTNGAYCCNGCNATH--- ------AAYYTNGTNTTYCARMGNATGTCNAARGAR------------------ATGGAY GARCAYAARGARYTNAARCAR---------------------------------AARCAR AAY------------------------------------GARYTN--------------- ---------------------------------------------------AAY------ ------------------------------------------------GCNTGGAARTTY ACNCCNGAYAGYCARACNGGNATGMGNYTNATGGGNAARTGYMGNATGYTNYTNCARGAR AAYGGNGARYTNGGNAARATGATHTCNTCNGGNMGNACNGCNMGNYTNGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ACNYTNTCNGCNGCNAARGARAARGARYTNYTNGAYAARATGCCNMGNATHGARAGYAGY GAYCCNGTNCCNYTNGAYGARACNGTNTAYTCNGCNTTYATGCCNAARGARAAYAARCAR AARGCNAAYGCNGCNAGYGCNAARGCNGAYGCNAGYCARAAYGGNAAYAARAARACNATH AAYCARAARAARAARAARCCNGAYCARGARCCNAARAARAARAARAARCCNGTNGCNYTN GARACNGCNYTNTCNACNYTNAARGCNAARGAYYTNGARTTYGTNYTNAGYCARTCNCAR AGYTTYTTYCCNGAYCAYCCNGTNGTNTGGYTNAARGAYYTNGCNTCNTAYYTNAAYYTN CARYTNGARGAYACNATHGAYACNGAYCCNGCNTAYAARGGNAARTCNTCNGGNTTYCCN YTNGAYGCNATHTCNACNGCNTAYGCNACNGTNYTNCAYACNTTYATGAARAARTTYTCN AARCARACNYTNGAYAGYATHTAYTAYTAYGGNATHCARACNATGYTNCARGARYTNGCN AARGGNAAYCCNGTNCAYGGNTTYAARYTNTAYYTNCARYTNYTNGCNTTYACNAARCCN GAYATHGTNGTNGAYAARYTNCCNCARTAYYTNGARYTNYTNAARATGCAYCARAAYAAY CCNGCNCARTGYYTNTCNGTNYTNTGGGCNYTNGGNCARTGYGGNTTYAARAAYTTYAAY TGYGGNYTNAARGTNTGGYTNGAYYTNATGYTNCCNGCNYTNGARGTNMGNCARGTNGCN CAYTAYCCNGTNGARTAYYTNGARGCNYTNATHCARTCNAAYAARAARACNACNAARAAR ------------AGYTTYGGNYTNGTNACNYTNMGNGARTAYTTYCARGTNYTNGAYGTN TTYTTYTGYCCNAARTTYACNYTNGCNACNGAYYTNAARAARMGNYTNACNGCNATGTAY CCNTTYATHAARACNYTNGCNTAYGGNGARGARCCNTCNCAYAAYYTNMGNACNTTYTTY CCNTCNTAYYTNGCNMGNTTYTCNTCNACNAAYTCNCARCCNYTNAARAAYGARYTNYTN CARTGYYTNACNCAYTGYYTNATHACNGAYAARCARTCNTTYAGYGTNTGGTGYCARYTN TAYACNAARCAYYTNTCNGCNTCNAGYCAYYTNYTNAAYCAYATHAAYGGNGARTGGCCN AARYTNTCNTCNAARTTYGAYAARAARATHYTNAAYGARACNYTNMGNTCNTTYTCNGTN ACNAAYGARGARYTNGARATHCARAGYAARGGNAARCARGAYGGNYTNAARYTNTGYCAR TCNGCNACNAARGAYYTNATGGTNAARYTNAAYGGNACNCAYTTYCCNTGGAGYTTYYTN GTNGCNTTYYTNGTNACNGTNTTYGCNGCNATHGTNGTNTAYGAYATHATGTCNAGYCCN AGYTTYMGNTCNTCNAARTCNATGCARTTYYTNGARCAYTAYGGNATHYTNTCNYTNYTN GGNAARACNTAYCARTTYATHAAYAAYGCNTTYACNYTNTCNATHAAYTGGYTNAARGTN AAYTTYCCNATHTTYTAYGCNTCNGTNMGNGAYACNGTNGGNCCNTTYYTNATHYTNGTN TGGGARTCNTCNMGNGAYTTYTTYATHAARGCNGARGTNGTNTCNMGNCCNTAYMGNGCN YTNATGGTNGARAARGTNGTNCARYTNTAYTTYTGGATHTAYGARYTNTCNCCNGARTTY TGGCAYMGNTGYGARGARYTNTCNTGGATGATGTGGGARATHYTNAARGAYTTYACNTTY AARATHTGGAAYCAYACNGTNCAYTTYGCNGGNGARGCNGARCAYTGGATHACNGARCAY GTNYTNACNGGNTCNTTYTCNAARAARGCNATHAARGAYACNGCNATGTGGGGNGTNGAR CAYYTNCARAAYTGYACNTCNTAYYTNGTNTCNTGG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARTTYGGNAGYGTNATHTCNAAYGTNMGNAAY TAYGGNAAYCARGAYGARYTNTTYGARCARATGAAYCAYATHGARGCNGAYATHGAYAAR AARYTNGARACNAARGARCAYGTNACNTGYAAYAARCARAARGCNGTNCARGAYYTNGAR GCNGARTCNGARGCNYTNTCNTTYAARATHAAYTCNTAYAARAARAGYATHAARYTNYTN CARGARGARYTNAGYCAYYTNYTNAARGARAARTCNYTNYTNAAYAAYGTNCCNGAYGGN GAYATHATGACNACN---AARATHAARCARYTNGARGCNGARGAYYTNATGTTYMGNAAR CARYTNGGNATGGARATHMGNAARGTNAARGGNGGNTGYYTNCARATHGCNTTYAAYCAR ATHGAYCAYAARCARCCNAAYTCNYTNTTYYTNTTYTCNYTNAARYTNGAYGARAAYMGN CARTAYATHGTNTCNGAYTGYAARCCNGCNATHTCNGAYGTNGAYAAYATHGTNCARCAR YTNAAYAAYGAYAAYGAYTTYCAYAARTTYATGCAYACNATGMGNCARAARTTY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNAARMGNMGNCAYAGYGAYGTNYTNCAR---GAYCCNTAYAARGGNCCNCARGAR TTYATGGARGCNGGNGTNMGNGGNTTYYTNATHAAYTCNGTNCCNGAYMGNGARGARCAY TCNYTNGAYGARGCNGTNAARTGYYTNMGNAARGCNTGYGTNAARYTNTAYGGNGGNATH MGNCCNYTNAARAARGARGAYGCNTCNTTYGCNAARGGNTAYGTNATGATHGAYTTYATG GARCCNGAYGAYGTNGTNCCNYTNCCNCAYCCNGAYGCNGAYAARGCNGCNGARGARAAR GTNAARGCNGARGCNGARCARGCNGCNAARGARGCNGGNAAR------------------ ---------------------------------------------------------GGN AAYGARGARATGGARGARGARAAYAARGARAARGARGARGCNACNGARGAYCARGCNAAR ACNGARAAYGTNGARACNGARGARACNAARGCNGTNGARACNAARGARGARAARACNAAR GARGARGARGGNGAYGARACNAARACNAARGARGARAARGAYAARGARGARCARAAR--- ------------------------AARAARGARGAYYTNAARAARAARAARAARGARGAR GARGARAARGCNAARCCNCCNYTNATGYTNGCNCCNCAYAARTTYAARAGYTTYMGNACN GARYTNMGNAAYATHATGTTYATHAARTCNGAYGTNGTNGAYCCNGTNGCNGTNATHAAY GCNGCNTTYGAYYTNATHATGGARAARAARCCNYTNTTYACNGAYAGYATHAAYMGNATH YTNCCNGTNCARGGNGTNTGYGAYAAYGAYTAYAARCARYTNGARATHATGTGYMGNMGN GTNYTNGCNCCNTAYGTNGGNGARCAYYTNGARGARCCNCCNAGYTTYGGNGTNATGYTN ATHGAYAARATGTGYGARCCNGGNGCNGARGTNYTNYTNGARGTNGTNMGNAGYGTNATH TGGTGYYTNAAYCCNATGGCNTGGCARAGYTCNCCNTGGTGYGARCCNGAYGTNACNATH CAYYTNGARATHATHGGNAGYAARATHATHYTNAGYGCNATGCCNCARTAYATGAARTAY MGNCARTAYAGYCCNTTYGCNYTNCAYGARYTNGGNCAYGGNAARCCNGARGAYGARGAY ------------------------------------------AARYTNGCNMGNGARMGN AARGAYGAYGAYGAYMGNGARAARGAYAARGGNAARGAYMGNGAYMGN------------ ---------------GGNMGNAARAARAARGAYTCNAAYAARAARMGNGAYGAYAARAAR AARGARGAYAARGARAARAARAARGAYGAYGTNGARAARAARGAYGARGGNGARAARAAR ACNGAY------------------------------GAYACNACNGARGARGCNAGYAAR ---------------------------------GARGARGARAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------MGNAARTCNGAYGTNTTYTCN GCNATGYTNGGNGGNGGNTAYGCNGARGCNGAYAARGTNGAYATHGARTTYTCNGAYGTN GGNYTNTCNGGNTTYGARTAYATHATHCAYTAYYTNCAYGGNTGYGARACNGGNTGYGGN GTNATHGAYTCNGTNATGCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ACNTAYGARGCNCAYCARAAYAGYAARTTY ATGCARAARYTNATHAAYAARAARGGNGCNAARACNAARAARCARTGGTAYAARCCNCAY YTNGGNGARCCNYTNGARGTNGARTCNAARAARACNAARAARGGNATHTCNCAYAGYCAY AGYGTNMGNYTNMGNCARCAYAGYCAYGTNYTNTAYGGNAARATHACNGARATHYTNAAY ACNGGNGARYTNTCNCARGARATHYTNGAYAARCARGTNTCNATHGTNTCNGTNAARATG CAYAARGAYATGAAYAAYYTNAGYATHTAYTGGGAYGCNGAYMGNAARGAYTCNGARTCN GTNGARCARYTNYTNCARGCNCAYTGYGGNAARYTNMGNAGYYTNYTNATHTCNTAYCAY ATHYTNGGNMGNATHCCNCAYATHGTNTTYGTNCARGAYAAR---ACNAGYGCNAAYYTN AAYCARYTNACNCARYTNTTYACNGTNGCNGAYTAYGGNCCNGAYTAYYTNCCNGGNAAY YTNCAYAARMGNACNCAYGGNGAYCARACNYTNAAYAGYYTNAAYATGCCNGARTCNGAY GAY------------------TTYYTNAARGARAARGTNGAYAAYGAYGAYTGYYTNAAY AAYTCNGTNGGNAGYMGNYTNGAYTGYACNGAYYTNYTNGAYGGNCAYGAYAAYAAYYTN AAYYTNGARATGCCNGCN---------ACNGCNAARGARYTNCAYTTYMGNTCNGAYYTN TAYGGNYTNAGYMGNGAYGARATGATGAARAARGTNYTNGCNAARAARAARAARCCNGAY ATGTCNGARGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNGGNCCN TCNGCNGCNTAYCAYGTNGGNTGYTTYATHMGNGGNAAYYTNTTYGTNCAYGGNGGNATH TCNGARATHAARACNTCNGTNCCNTCNGCNCARYTNTAYAARYTNAAYMGNCAYACNACN YTNTGGGARAAYATHMGNACNCCNGGNAGYCCNGCNYTNAGYCAYCAYGCNTGYGTNGTN AGYGARGAYMGNTAYATGATHYTNATHGGNGGNTGGAAYGGNAARMGNMGNTGYGCNGAY GTNCAYGCNTAYGAYACNCARGARGAYMGNTGGATHTCNATGAARCAYTCNGGNTTYCCN GAYGGNGCNGGNYTNAGYTCNCAYACNGCNTCNATGYTNYTNAAYGGNGAYATHYTNATH GTNGGNMGNGARGGNAGYYTNMGNATHCARMGNAARAAYGGNAAYGCNTAYATHYTNTCN GGNAGYGTNYTNTCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYTTYCARGCNGCNGARGARGCNMGNTTY------ATHAAYAAR ACNCARCCNGGNTCN---MGNCARCCNATGGARGGNYTNATHYTNAARTTYACNAAYGTN ATGAARGGNTAYCARTAYMGNTGGYTNGTNYTNGAYCCNGARTCNGGNATGYTNGARTAY TTYGARAARGARGARCAYAARAARCARMGNCCNMGNGGNTCNGTNCAYYTNGCNGCNGCN GTNGTNTCNCCNTCNGARGARGAYTCNCARACNTTYATHGTNAAYGCNGCNAAYGGNGAR ATHTAYAARYTNMGNGCNTCNGAYGCNAARGARMGNCARTCNTGGGTNGAYMGNATHMGN TCNACNGCNGARCAYCAYACNGCNAAYATHGCNCARCAYTCNCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARTGGTGGGTNAARTTYMGNAAYCCNCARGAYATH YTNAARCAYCAYGARTCNTAYYTNTAYTGYGARATHGCNTTYTAYGTNYTNGCNTTYATH ACNTTYTGYCAYGCNYTNGCNAGYGGNGGNMGNTAYAARTGGYTNTGGTTYGCNACNGTN GCNCAYGGNATHACNGTNGARTGYGTNAGYTAYTTYYTNCCNGAYATHGAYAAYTTYTGG CAYGGNCARTCNATGGTNATGYTNATHGGNCARMGNYTNCCNYTNCAYATHATGYTNGTN TAYCCNGTNTTYATHTAYACNGGNGTNGTNGCNGTNTCNTAYATGAAYYTNMGNTGGTGG GCNGARCCNTTYGCNGTNGGNYTNTCNGCNGTNYTNATHGAYGTNCCNTTYGAYATHATG GGNATHAARYTNGTNTGGTGGACNTGGCAYGAYGAYGAYCCNAAYATHTAYGAYMGNCAY TAYTGGGTNCCNTGGACNTCNTAYTAYTTYCAYGCNGCNTTYGCNTCNTCNTTYGCNTTY ATHTTYTTYGGNATHAARAARYTNTTYTGYTGYMGNGGNYTNAARTTYCARAGYAAYGGN TTYTTYATHGARYTNCCNGCNYTNATHYTNACNGGNYTNTTYTCNATGCCNYTNGGNGTN YTNCARTTYATHCCNGTNTAYCAYTCNYTNCAYGAYYTNYTNAARATHCAYTCNGARGTN AGYGTNYTNYTNTTYYTNGCNTTYTAYGCNYTNGTNGTNTGGAGYTCNGAYMGNMGNCCN TCNGARATHGCNMGNYTNAARMGNGGNGGNYTNTTYAAYCCNATGATGYTNGTNATHTTY TTYCAYTAYGCNTTYTAYGTNTTYYTNGTNTTYACNGCNGAYCCNACNTCNATHAARGCN ATHGGNYTNCAYCARCCNGTNGGNCCNTGYAAYAARACNGTNAARGTNCARACNCCNACN GGNCAYATGYTNAGYAARACNCAYTAYYTNTGYYTNAARAAYTAYTCNGARGAYTAYTTY ACNYTNGAYTGYYTNAARAARCCNCCNGCNGAYAARACNGARTGGTAYACNATHTGYGGN ACNGCNTAYCCNAAYCAYAARGARTAYATHGTNGTNGTNTGYGCNTTYTGYGCNYTNGGN YTNYTNTGGTTYTAYCARGCNYTNTGYMGNTCNGGNATHCARCCNMGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY ATHCCNACNATHTTYCAYACNGCNTCNATHTGGYTNACNATGGCNYTNGCNATHCARMGN TAYATHTAYGTNTGYCAYTCNTTYAARGCNMGNGCNTGGTGYACNATHMGNAAYGTNATH TAYGGNACNATHGCNATHTAYGTNGTNTCNATHYTNAGYCAYATHATHMGNTTYTCNGAR TCNTAYCCNGTNCCNACNTAYMGNCCNTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AGYMGNAGYCCNAGY CCNMGNGAYGGNAARGTNATHAARTTYGGNGAYAARGTNATHAARCCNGGNGCNAGYTTY GGNMGNCCN------TCNTCNAAYTTYTCNAARCCNYTNACNTTYAARGARAARATGMGN CARCARYTNATHAARGCNATHGARGAYGGNGCNGAYACNAAYGARGTNYTNGCNAAYAAR GGNGGNTCNACNATHTGYACNCARAGYGCNGGN---GTNATGCARCARGTNATHCCNAAR CCNAARGGNCCNCCNATHCCNYTNATGGAYGCNATHGTNTCNTCNACN---AAYYTNTCN GCNATGACNGTNACNGCNTCNGARGCNGCNATGCARTCNATGYTNGCNYTNCARAARGAR GCNACNGARAARACNGGNATHGARATHCCNAARTAYTAYAAYCCNGCNGCNATHAAYCCN ATGAARTAYGCNGARCARGTNCARAARMGNAARYTNYTNTGGTCNAARGCNAARGAYAAR GAYGTNAAYTCNCARTGGCAYGCNACNAGYYTNTCNGGNGAYGCNGAYGAYAARTCNAAR GARAARTTYMGNAARYTNATGGGNATHAAR---------------GARGAYCCNGTNAGY AGYTCNGCNGCNGARGGNGARCARGARGARAARCARAARCARATHTTYGAYCARYTNAAY AARGARTAYGARTTYGCNMGNATGACNACNCAYACNCAYMGNGGNGTNGGNYTNGGNTTY GGNTCNACNGGNTAYCARCCNCCNCCNACNACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GGNAARGTNCCNGCNTAYATGCARGTNCCNGAYATH CCNTCNAGYCAYAARGAYTGYYTNTGGAAYAARAARMGNGCNGAYAARAGYGTNTCNGCN YTNGAYTCNACNGARGARAGYAARATHYTNAARGCNATGTCNGGNTTYTCNYTNCCNGTN GARAAYGTNCCNGARTGGGCNMGNGAYATGTCNGARGAYGARTGGAAYCARCAYATHGTN CARCARATHAARCCNGGNGARGARAGYGGNCAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TTYAGYYTNAAYYTNTGYGTNGGNCCNACNTAYGAYCAR GARTGYGCNYTNCAYTTYAAYCCNMGNYTNGAYGAYAAYAARGTNGTNMGNAAYAGYYTN CARAAYGGNTCNTGGGGNAGYGARGARACNGCNGGNGGNTGYCCNTTYMGNMGNGGNCAY GGNTTYGARATHCAYATGAARGTNCARCAYCAYGGNTAYAAYGTNACNATHAAYCAYMGN CAYTTYTGYGAYTTYAAYCAYMGNATGCCNAARGARAGYGTNCARTAYATHTAYATHGAR GGNGAYGTNGCNATHAAYTTYATHCARTTYMGNGGNGGNCAYTCNCARCAYTCNGCN--- ---CCNGCNGTNCCNGGNTAY------------CCNGCNTAYCCNCCNCCNCCNTCNTTY CCNTCNGGNCCNTCNTAYCCNCCNGCNCARNNNTAYCCNCCNACNCCNGGNTAYCCNGGN GCNGGNAGYGGNCCNGTNTAYAAYCCNCCNGTNCCNTTYACNTCNCCNATHGCNGGNGGN YTNTAYCCNGGNAARATHATHTAYATHACNGGNGTNCCNAAYCCNAAYCCNAGYMGNTTY ACNGTNAAYYTNCARTGYGGNCCNTAYGAYTCNGGNGAYTTYGCNATGCAYTTYGAYGTN MGNTTYAAYTAYGGNAGYGAYMGNAAYCARGTNATHMGNACNCAYAARCARGGNGGNAAY TAYGGNGGNGARGARAARGGNATHACNCAYTTYCCNTTYTAYCCNAAYGCNAAYTTYGAR ATGATGATHYTNACNGARCCNTCNGGNTTYAARATHGCNGTNAAYAAYCARCAYTTYGTN GARTTYAAYCAYMGNYTN---CCNTTYAAYTGYGCNGAYCAYATHAAYATHGTNGGNGAY GTNMGNYTNTCNCARGTNMGNTTYCAR---------TTYGTNCCNAAYTTYYTNATHAGY TCNGGNACNGGNYTNACNCCNACNYTNACNCCNACNACNYTNGCNACNATHGARCARTCN TTYATGGARATGCARCAYTCNGGNGCNMGNGAYCCNGTNACNCARAGYGGNTTYGTNCCN CCNGTNGTNGARCCNACNAAYAAYAAYAGYGCNGAYCARTCNCARGAYAGYTAYGAYAAY TCNTCNTCNGAYTCNGARTGGGARCCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GAYCARACNYTNGGNGAYGTNACNAARAAR ATHAAYGAYGCNAAYMGNYTNATHGARACNATGACNGCNYTNGARAARYTNMGNYTNATH MGNCARGAYGCNGCNAARAARMGNGGNGAYAAYGAYATHGGNGARTCNMGNCARAGYTTY GARCARAARATHGCNGAYATGACNMGNYTNGTNMGNTCNCARYTNGARGTNTAYAARGAR GARGARCARCARYTNMGNAARATGATHAARTCNGARCAYGARGARTCNAGYAARAARGAR AARCARYTNCARGARGARAARGAYCARCARGARCARGARCARAARGAYGARGAYYTNMGN AARATGTTYTTYGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TAYYTNTAYTGYCCNTAYGAYGAYACNCAY GARATHYTNGCNAARAGYTTYAGYGCNCAYYTNATHAARTGYMGNMGNAAYCAYAGYGGN CAYAARYTNGTNTCNTGYCCNYTNGAYAGYACNCAYAARATHCCNAARCCNGARATGCCN TAYCAYYTNTCNGTNTGYGAYAARMGNTGYYTNATGGAYMGNGARATG------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CARCAY YTNATHAAYYTNCARGCNAARCAYACNGTNTAYATHTTYGARACNACNGAYCAYATGAAR ATGGCNCAYGCNGCNGGNGTNAARCAYATHAARAGYACNAARGCNTTYMGNAAYTCNGAR CARATHYTNAGYAGYYTNTGYGTNAAYCCNTCNGTNCCNGTNATGYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATHGARACNYTNMGNGGNMGNTTYGCNCCNGTNGTNTGGGARGARATGGCNCAR YTNCARCARTTYGCNACNTCNGARGGNTTYGARCAYTCNYTNGARATGTGGGAYATHAGY TAYTGGMGNMGNMGNCAYMGNGARCAYYTNTAYAGYGTNGAYAARAAYGCNGTNAARCAR TAYTTYCCNGTNAAYTCNGTNYTNYTNGGNYTNTTYGAYYTNTGYACNAAYYTNTTYGGN ATHAAYTTYGARGARGTNACNCCNGARGTNGARATGTGGCAYTCNGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGGAR AAYAAYAAYGCNATHGCNGCNAAR---TCNYTNGARGGNGARACNAARATHGARAAYGTN AARCCNACNGCNGAR------GARAAYTCNGGNAAYMGNGGNTTYMGNTAYAAYMGNMGN MGNCARCARTTYMGNMGNGARGTNAAYCCNGARGAYGARACNGGNAARGCNGCNATHMGN MGNAARATHTGGGAYAAYYTNGARGAYAAYAAYYTNGTNTCNGCNCCNMGNCCNTGYCAY TAYMGNATHCCNAAYTTYGARGGNGCNTCNGCNGCNGCNGAYCAYYTNAARTCNYTNGAY GARTTYAARAAYGCNMGNACNATHAARGTNAAYCCNGAYAARGCNCARGARCAYGCNMGN TTYYTNGTNYTNGARGAYGARAARGARYTNGTNYTNYTNAAYCARAAYCARAARGAYYTN ATGGTNCCNACNCCNGARYTNAARTCNGGNYTNYTNAAYMGNGTNGTNCCNCCNGARGGN GCNAAYAARGARGARYTNMGNCAYTGYTGYACNACNCARGGNGTNAARGARAAYAGYAAR GARATHGCNYTNGARGAYAARATHAGYYTNGAYYTNATHATHGTNGGNAGYGTNGCNGTN TCNMGNAAYGGNTCNMGNATHGGNAARGGNAARGGNTAYGCNGAYYTNGARTAYGCNATG ATGMGNACNATGGGNGCNGCNAAYGCNAAYACNGTNGTNGTNACNTCNGTNCAYGAYTCN CARGTNGTNGARATHCCNGAYGAYYTNGTNGAYGARCAYGAYATHACNGTNGAYTAYATH ATGACNCCNACNGARYTNATHAARACNAAYGCNAGYMGNCCNMGNCCNTCNGGNGTNACN TGGAGYCAYYTNGCNGTNAAYAARTTYTAYCARATHCCNGTNYTNMGNCARYTNMGNAAR AAYGARMGNGAYGAYGGNAARGAYGTNYTNYTNAARGAYCARAARGARGARGAYGARGAY CCNGTNGAYGCNATGGARCCNCCNMGNCCNMGNMGNTAYGTNMGNTAYTAYCARAAYGCN GGNGGNTTYMGNGGNGGNGGNMGNCCNTTYGGNGGNMGNTTYMGNMGNGGNAGYGGNMGN MGNMGNCARGAYGAYAAYGGNGARGAYAGYAAYAARGARAAYATHGAYGGNGGNGARGAY TCNGGNGCNGAYGGNGAYAAYGARGGNMGNGTNGGNAAYMGNMGN--------------- CCNCCNCCNMGNAAYAAYTAYMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARCARMGNYTNGARCARMGNCCNCARGAYGTNAGYGAY YTNGARMGNCARTAYYTNGCNCARTGYACNAGYGARGARCARMGNCARGCNYTNATGGCN TCNGGNGCNTTYGGNAAYGAYTCNACNGCNATGGCNGCNYTNAGYGCNTTYTAYGGNCAR YTNGGNATGGAYATHGCNATGCCNGTNACNAARGTNGTNGAYACNTCNGGNMGNGGNATH AAYYTNGTNCCNTTYMGN---------GARYTNTTYATHTCNCCNCARTTYAAYGARGAY GCNGTNAAYAARATHGGNGAYTTYCCNYTNMGNGARGARGAYGTNYTNYTNGTNAGYTAY CCNAARTCNGGNTGYCAYTGGGGNTGGGARATHYTNMGNATHYTNGARTCNGGNAARATH AARGAYGAYGCNGTNAGYAARGARGAYTTYATGATGGARTGGCARCCNTCN--------- ATGGARTCNYTNCCNAGYACNMGNGTNYTNAAYAAYCAYATGCCNTTYCAYYTNCARCCN YTNGAYYTNYTNACNAARAARCCNAARGTNGTNYTNYTNTAYMGNAAYTTYAARGAYGTN GCNGTNTCNTTYTTYCAYCAYCAYGTNGCNATHGARGAYTAYGARTAYMGNGGNGAYGAY TTYGGNTCNTAYYTNCARMGNYTNYTN--------------------------------- ------------------------------------------------------------ ------------------GAYGGNCARGTNGARAGYGGNAAYCCNTTYGTNTTYACNAAY GGNTGGGARAARGGNATGMGNGAYAAYCCNGAYYTNCCNGTNTAYTGYYTNGCNTAYGAR GARATGMGNCARAAYCCNATGTCNGARATGMGNMGNYTNTGYGAYTTYYTNGGNAARGAY TAYGAYGAYGAYTTYYTNCARCARGCNTGYGAYGTNACNAGYTTYGAYTAYATGAARAAR ACNAARGGNGTNGCNAAR---------------CCNATHTTYTAYMGNAARGGNCARGTN GGNGAYTGGAARAAYYTNTTYACNGTNACNATGAAYGARTGGTTYGAYGAYATHATHCAR ACNGARATGGCNGAYACNCARYTNAARTTYMGNTAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNAGYAARACNGCNAAYTAYGTNATHAARGTN GCNCCNTTYATGACNGARACNCCNYTNAARTCNTCNTCNTTYTTYCAYTCNGAYGTNTTY AAYGAYYTNGCNGTNCAYACNTTYCCNMGNTCNAARYTNGAYACNGCNCCNACNGARTTY TGGGARTCNAAYGCNGARCCNAARTAYAGYGAYGAYGAYGTNGARATHGTNMGNAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ACNGAYMGNAGYGGNATHAARGARTAYYTNCARAARGARGGNYTN GTNATHACNMGNGCNAARACNTTYYTNCARAARCARMGNMGNACNYTNAARCARMGNCAR TCNGCNYTNGCNGCNGCNAARCARGARYTNGTNAARGAYAGYAGYATHYTNCARCARGGN AAYCCNACNGARGGNGCNACNGARATGYTNGARAARGTNMGNGAYACNYTNGARTCNGAR MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CARCAYGARAAYATHGTNACNYTNTAYGGNTAYGCNYTNGAYGGNCCNGARYTNTGY YTNGTNTAYCARTAYYTNAGYAAYGGNTCNYTNGARGAYMGNYTNYTNMGNAARAAYGGN ACNYTNTCNYTNTCNTGGCARTGYMGNYTNAAYATHYTNGTNGGNTCNTGYAARGCNATH AGYTTYYTNCAYACNATGGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GTNTGYGCNGGNTCNGGNTCNAGYGTNYTNAARCAY GCNAARGCNGAYYTNTTYYTNACNGGNGARATGTCNCAYCAYCARGTNYTNGAYGCNGTN CAYGCNGAYAGYCAYGTNATHYTNTGYCAYCAYTCNAAYACNGARMGNGGNTAYYTNAAR GARYTNGARAARMGNYTNGCNAARATHYTNGAYAARTCNGTNAARATHTTYATHGCNGAR AGYGAYMGNGARCCNYTNGARATHGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GCNYTNMGNGGNCARCCNYTNCARCCNGGNGAYTGYYTNGGNTGYAARYTNGTNGGN ACNTCNGTNATGGTNGCNAGYGGNATHATHGTNYTNACNTCNGCNACNGTNGGNMGNAAR MGNATHTAYGCNGAYGAYYTNTGYYTNGCNACNCARTCNCARGAYTTYAARACNATHGAR GAYMGNYTNTCNTCNTCNYTNAAYTCNYTNACNACNTAYTAYAARCARAAYTCNYTNAAY GCNAAYCCNGGNAARACNCARGTNTGYGCNTTYCAYYTNAAYAAYCAYCARGCNAAYMGN AARYTNAAYATHACNTGGAAYGAYAARGCNYTNGARTAYAAYACNTCNCCNGTNTAYYTN GGNGTNACNYTNGAYMGNACNYTNTCNTTYTCNCARCAYATHACNAARGTNMGNGCNAAR GTNGCNACNMGNAAYAGYYTNYTNGGNAARYTNGCNAAYACNAARTGGGGNGCNGAYCCN ACNACNYTNMGNACNACNGCNYTNGCNYTNTGYTAYTCNTCNGCNGARTAYTGYTCNCCN GTNTGG------GCNMGNTCNAGYCAYGCNAGYAARATHGAYCCNCARYTNAAYAAYGCN TGYCAYATHATHACNGGNACNYTNAARCCNACNCCNGTNCCNGCNGTNTAYMGNATGGCN GGNATHGCNCCNCCNCAYATHMGNMGNGAYACNCARACNAARGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARMGNGTNAARTTYAAYACNTCNGGNMGNAGYCCNYTNATHGCNCAYTAYYTNCAY ATGMGNCARYTNMGNAAYTAYAARCARCCNGGNGTNAARGTNMGNMGNACNGARATHYTN AARYTNCCNCCNGAYGGNCCNACNTAYCARCARTTYATHGCNAAYACNYTNAGYAARGCN GARTCNYTNGARMGNGARTAYACNMGNATHTGYGARCARACNTCNACNGCNATHYTNGAR YTNGARMGNCAYAARMGNGAYTCNAAYMGNGARATHGCNGARYTNAARAAYGCNYTNACN AAYATHAARAGYATHCCNGARMGNMGNTCNYTNATGGAYAARATHTCNGARTAYAARGAY YTNGTNATHAARGARAARCCNYTNYTNGARGTNTCNATHTCNCARACNMGNACNAGYTCN TCNTAYTCNTCNGAYGARGARGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARTCNACNCAYTCNTCNMGNYTNAARACN---TCNTCNCCNTCN MGNCCNGGNTCNGCNCCNTCNCCNGGNMGNAARAARGARGTNAAYTTYGAYYTNGAYMGN ------AARTCNCCNYTNCCNTGGATHCCNGCNGGNTGYMGNCCN------TAYAARCCN AGYCCNMGNTCNTCNAGYGCNGARMGNATHCCNTTYTTYGTNMGNTCNYTNGARGGNCAR GAYGTNMGNGAYGTNATGCCNGARMGNMGNAGYGTNACNATHCARGAYAGYCAYAARGAR GGNGCN---------TTYGGNTAYMGNTCNYTNCCNACNGAYMGNCARYTNMGNTCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNCARAGYGGNAAYACNGCN YTNTCNYTNTCNATHGCNTAYMGNCAYGAYCAYYTNYTNCCNYTNTTYYTNCAYCARTCN AAYGTNAAYACNMGNGAYTTYGAYCAYGAYACNCCNYTNATGTTYGCNGCNTGGAAYAAR CARCCNMGNATHYTNTCNACNYTNATHCARTGGGGNGGNGAYGTNAAYGCNGTNAGYAAR TAYGGNACNACNGCNYTNTGGAAYGCNGTNTAYMGNTCNTCNCCNGARAGYGTNYTNGTN YTNYTNAGYCAYAAYTCNMGNATGGAYGTNGARTGYGARGGNACNCAYYTNTTYTCNGAY GAR------GAYGAYTGYAAYGARGARAARGTNMGNAARATHTAYCCNGGNCAYAARMGN TCNGTNYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATGGCNTCNTCNACNTTYYTNYTNYTNGTN---YTN GTNGGN---------GCNYTNGGNYTNGTNACNTGYCARMGNGAYMGNYTN--------- ---TTYGARMGNYTNGAYMGNGARMGNGGNMGNGARMGNGAYMGNGARTTYGTNAGYATH GGNGARGGNTGYACNGGNAARGTNATGGAYGTNTTYTTYATHATGGAYTCNTCNTCNTCN ATHTAYATHAAYGAYTAYATGTCNCARCAYAGYTTYGTNMGNGAYGTNATHAGYMGNTTY GAYGTNAGYCCNGARAGYACNMGNGTNGGNATGYTNACNTAYAGYGAYGAYYTNGARMGN CCNGTNATHTCNYTNAAYMGNTAYACNGAYAARAAYGARYTNYTNAAYGCNATHTCNATH AGYAAYYTNCCNTAYMGNACNGGNATHACNAAYACNGAYYTNGCNATHMGNTAYGCNMGN CARATHTCNGARTTYMGNCARGAYATHACNAARGTNYTNGTNGTNATGACNGAYGGNGGN TCNAAYTCNCCNGCNTCNACNGCNMGNGARGCNGARYTNGCNMGNAAYGCNGGNTTYTAY YTNTTYGTNGTNGGNATHGGNCARTAYMGNGARGARMGNGARTGGMGNTCNATHGCNAGY GAYCCNGAYTCNAGYTTYGTNTAYAAYATHACNACNCCNMGNTTYATGGARGAYGTNAAR TTYACNYTNCCNCCNCARGCNTGYTCNYTNCCNCCNATHATHATHGGNGGNTCNTGYAAY GTNAAYCARYTNTCNGARGTNTAYTTYGTNGCNTCNMGNAGYGCNAGYAAYAARGCNATH GAYYTNATHGARAAYTTYAARMGNMGNACNMGNGAYCARMGNGAYAGYYTNMGNYTNAAY TAYATGATHGARGCNTGYGGNTCNGTNACNAAYGCNGCNYTNGAYGAYGARGAYGTNATH ---TGYGAYMGNTTYGGNMGNMGNAGYGGNGAYACNAARGARTCNGTNGAYGCNYTNTTY GTNMGNGCNMGNGCNACNGARTCNMGNAAYGAYGGNGGNMGNGAYGCNGCNCARGTNATH GTNYTNTTYGCNGAYGAYCCNACNATGAGYYTNAGYMGNTTYTCNTGGTCNGAYAAYGCN MGNAGYTCNGARAAYTTYGAYGAYGTNACNGTNATHATHGTNGAYYTNGGNATGMGNACN TAYGGNGAYTTYGTNCARMGNATGYTNCCNAAYMGNAAYAAYATHATHMGNTTYYTNGGN GGNGCNYTNGAYAAYCARTCNAAYATHCARMGNCARTTYYTNGAYACNACNTGYTCNGCN ------------------------------------------------------------ ---------GAYGAYTTYGARAARGTNGAYGCNCCNGGNGGNGGNTTYGGNCAYGAYGAY ATGACNGCNGCNGCNTCNGGNGCNTAY------GAYYTNGAYCARGAYGCNGARATHTCN ACNACNACNGAYGTN------GCNGGNGARGARGARGCNGARGCNGAYMGNTTY---GCN ATGGGNTCNCARGAYACNAAYGCNTAYCAYCCNTCN---GARCCNYTNATHTCNTGGGGN GAYGAR---------------------------------GAYGAYGAYGARGTNACNTCN CARGTNCARCCNTCNGCNCCNGTNCCNGARAGYATHGAR---GARCCNYTNYTNAAYTTY ---GAYGAYAGY---CCNTCNGTNGAY------GAYTTYATGCCNTCNGTNAARCARCCN GTNCCNCCNTCNAGYACNACNCCN---GARCCNAAYAGYTAYCCNYTNCCNACNCARYTN GAYGARTTYATHGARCCNAARMGNGARGARAGYGARACNGTNAARGARGARAGYAARCCN GTNTCNGAYCARACN------ACNGTNGARGCNGCNGARGGNTCNTGGYTNAARGGNGTN GAYCCNMGNGARGCNGAYGTNGGNGARGCNGTNTCNCARGGNYTNATHGAYYTNATHTAY TGGMGNGAYGTNAARACNACNGGNGTNGTNTTYGGNGCNATGYTNGTNGTNYTNYTNTCN YTNGCNATHTTYTCNYTNYTNAGYGTNYTNGCNTAYYTNTCNYTNGCNGTNYTNACNGTN ACNTTYAGYTTYACNGTNTAYAARAARATHATGGGNGCNGTNCARAARTCNAAYGAYGGN CAYCCNTTYAGYCARYTNATHAAYATGGAYYTNACNYTNAGYGARGAYAARYTNAARAGY ATHATHCARAGYTTYYTNAARAAYGTNAAYTGYACNGTNAGYGARYTNMGNMGNYTNTTY YTNATHGARGAYATGGTNGAYTCNATHAARTTYGGNYTNYTNYTNTGGGTNYTNACNTAY GTNGGNGCNTGGTTYAAYGGNATGACNYTNGTNATHYTNGTNGTNATHTGYGTNTTYACN YTNCCNAARGTNTAYGARACNTAYAARGTNCARATHGAYAAYTAYYTNGCNYTNGCNAAR GCNCAYGTNGAYAAYGTNYTNAAYATHGTNCARAGYAARYTNCCNTTYYTNAARAARAAR GARAARGCNCAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYGAYTCNTGYCAYYTNGCNCCNGAYTGGAAYATHCAYCCNTTY YTNGCNTCNGAYCARGGNYTNTCNTTYAARYTNGCNGCNMGNGARMGNATHCARAGYTGY YTNAARTCNCAYACNTTYTCNCAYGAY------------------------GARMGNGAY GAYCARGARAAYGARATHTTYCAYYTNCCNGARATHAGYACNGAYACNGTNATHTAYCCN YTNATHCARATGGGNCCNYTNGGNATHCARAAYGAYGARAGYGCNACNGTNGAYYTNTTY YTNMGNTCNGARCARCCNGAYYTNATHYTNYTNACNTCNGGNTAYTTYAAYYTNACNAAY CARTAYGCNGAYGTNATHGTNGAYGAYGCNGAYGCNAARTTYAARATHYTNATGGCNTCN CCNAARGCNAAYGGNTTYYTNGGNGCNMGNGGNATHGCNGGNGCNGTNCCNTAYTCNTAY ATHTAYYTNGCNCAYCARTTYTAYAAYAARGTNGTNAARGCNGGNCAYTCNCAYMGNATH CAYATGYTNGARTAYGARMGNGARGGNTGGACNTTYCAYAGYAARGGNYTNTGGTAYTAY YTNAARAAYGARCAYYTNCCNMGNYTNACNYTNATHGGNTCNCCNAAYTTYGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATHATHGARTCNAARCCNTCNGARACN---AAYAAYTGYAAYGTNTAYMGNTCNACNATH TCNYTNGAYGCNCCNYTNAARGTNGTNGAYGARACNTTYCCNYTNTGYCCNTTYACNACN CAYAARGARTGGGCNCCNGAYATHGCNGAYGTNATHYTNYTNGARTCNYTNGARGAYGGN ATGATHGTNTTYCARACNACNACNCCNMGNATHGCNMGNATHATHTCNCCNMGNAGYTTY GTNACNGTNGGNGGNTCNGAYMGNGAYGGNACNMGNGTNGTNMGNTAYGCNGTNAGYATH GAYTAYCCNAARMGNYTNGAYGARGARGGNATGGTNMGNGGNATHAAYGGNCCNTAYGGN GCNMGNTTYACNYTNGAYTCNAARAAYACNAARAARACNMGNGCNGARYTNATHATGCAR ATHGAYTTYCARGGNAARATHCCNMGNAARTTYGTNGARACNAGYATHCCNGCNTCNATH GTNAAYTCNTAYGARGCNTAYAARACNTAYATGAAYAARAAYGAYYTNTTY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARGAYTCNGARTGGGARGCNGTNACNATHGCNTTYAARGARMGNGARATHGCN GTNAAYMGNGCNAGYGARYTNGTNGAYGARGCNMGNAARAGYATHGARAARATGAARMGN GTNGTNGAYGARGCNAARAGYAAYAARGTNACNATGAARAAYTCNGCNATHTAYCCNGCN ACNAARAARYTNTCNGAYTTYAAYAARGARATGTCNACNGCNGCNGCNCARGTNMGNCAR GCNGARTCNGAYGCNAARGTNATGYTNAARTAYAARGAYYTNATHGAYAARGGNAARMGN CARTTYCARYTNGARGTNGARAGYYTNATGCCNGAYAGYAARGGNGGNAARGCNGGNMGN AARATGACNGAYGARGARYTNAAYGCNYTNATHGCNCAYGCNCAYMGNMGNATHGARCAR YTNCARAARCARATHGCNGARCAYYTNGCNATGGARCARAARMGNYTNGCNCARTCNYTN GARGCNCARAARCARGARGAYMGNTGYATHACNGARTCNGCNGTNAARGAYGARCAYGAY MGNYTNAAYCARGARTTYGAYYTNGARAARCARAARATGGARYTNGARTTYTAYGCNMGN ATGGARACNGAYGTNMGNAARCARYTNAGYMGNCARGCNGCNGCNCAYAGYGAYCAYYTN AARGAYGTNYTNGCNATHCARGARAARGARYTNAAYGTNGAYTTYGARMGNCARATGAAY GTNAARYTNYTNGARGARMGNGARAARTTYCARACNGARACNTCNAGYTGGATHTCNMGN YTNAARGGNATHGARGCNGCNGTNGAYGCNMGNGCNGCNAGYGARAARYTNGCNMGNACN GCNCARGAYYTNTGGYTNGCNTGYATHGCNYTNAAYTCNACNATHYTNTTYGGNAAYGAR GAYGARAGYCARTCNYTNACNCCNYTNCARCAYCARGTNGARGCNGTNGTNAAYTCNGCN AAYAARCAYCCNTTYGTNGARACNGTNGCNAAYTCNATHTCNCCNGTNGCNYTNGAYMGN GGNATHTAYACNGARAGYGAYYTNMGNGAYMGNTTYGTNMGNGTNGCNCARGTNAGYMGN MGNYTNGGNYTNATHYTNGARTCNAAYGCNTCNYTNTAYAARTAYYTNGTNTCNTTYYTN CAYTCNTTYATGCAYATGAAYACNGTNGCNGCNTAYTCNGARAARGAYYTNATHTCNYTN GAYGARATGGAYAAYTTYGARYTNGTNGCNAAYGCNCARTAYTGGATGGARAARGGNAAY YTNGARATGGCNGTNMGNTTYATGTGYCARYTNAGYGGNGARTCNCARGTNGCNGCNAAR GAYTGGATHACNGARGCNATGYTNYTNYTNGARACNMGNCARGCNGCNAAYACNATHATH GCNTTYGCNTCNGCNACNGGNYTNGCNGCNACNTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARTCNTCNTCNGAYTCNGGNTTYGGNGGNAARGGNGGNTTYAGYTCNCCNTCNTCNTCN ---TCNTCNTCNCCNTCNTAYGCNGGNAGYCCNGTNGAYTCNAGYATGGCNCAYAAYTCN ACNAAYTCNAAYGAYACNGAYCAYGAYCCNCAYGGNACNMGNACNYTNGCNCAYCARGTN GCNCAYAAYCAYACNTAYAAYACNYTNCCNGGNCAYGTNCCNMGNGARGTNAARAARTAY GCNCCNAARGARAAYAGYAARAARGGNCCNCARTGYMGNGAYGARAARMGNGCNCARGAR YTNAARATHCCNTTYACNGTNGARCARATHGTNGARTCNCCNGTNGARACNTTYAAYGAY ATHYTNACNAARTAYAAYYTNAAYGARGARCARYTNTCNYTNGTNMGNGAYATHMGNMGN MGNGGNAARAAYAARYTNGCNGCNCARAAYTGYMGNAARMGNAARGTNGGNGCNATHGTN ACNYTNTCNGAYGARATGACNGAYYTNCARAARGCNMGNGAYMGNYTNAARGCNGARMGN GCNGARATGGARAARGARACNMGNAARATGAARGARAARTTYGGNCAYYTNTAYACNCAY ATHTTYCARTCNYTNMGNGAYGARCAYGGNCARCCNTAYGAYCCNAAYYTNTAYTCNYTN CARCARTCNAGYGAYGGNAAYGTNTTYYTNGTNCCNMGNAAYGTNACNAAYGGNATGAAY ACNAGYMGNACN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGYTNAAYAARGTNACNCCNYTN YTNMGNATHGTNCCNMGNGTNMGNAAYGTNMGNTCNATGAGYGGNGGNCAYGAYGTNCCN GCNCAYTTYAARACNATHMGNCARATHTGYGARGARAAYAARAGYCAYATGAAYTTYATG CCNGTNCCNGCNGGNTCNTGGCARGARGCNCAYAAYGCNACNCAYGCNAARAAYAAYAAR YTNYTNATHGCNAGYGTNGTNGCNGTNGTNGGNACNTTYACNATGYTNTAYTCNACNGGN TGYTTYTAYYTNCAYGGNGCNCCNCCN---------YTNAARGAYAARGGNTCNAARATH AARGTNCCNCCNAARYTNGGNAARYTNGTNGCNGARAAYTAYGCNYTNTCNGARAARTGY TCNACNGCNAARYTNGTNAARAARGTNCCNGAYGCNGAYGTNGCNCARAAYTTYATHGAY MGNYTN---AAYGCNCARAAYGAYGTNAGYCARGARATGTGGGCNMGNGCNAARGCNATG TCNTGYYTNCARAGYCAYCARYTNATGYTNAARTCNYTNCAYTCNYTNGGNATGGCNAAY YTNACNGARAAYGCNTCNTTYGARACNATHTAYMGNACNAARMGNYTNYTNGARTTYATH YTNTCNACNTTYGCNCARACNCARGARGARGCNGAYTAYTTYTCNMGNGTNCARTTYMGN CARACNAAYGGNGCNAGYCARACNGTNTCNTCNCAYMGNGAYAAYTTYGTNAARTAYYTN TTYTCNAAYCARGAYAAYGARTCNCARAARCAYCAR------MGNGAYMGNTTYGTNAAR GCNGCNYTNCARTGYACNAAYATHTGGACNCAYYTNCARTTYGARMGNGAYYTNTGYGAR YTNCARYTNCAYYTNYTNTCNYTNACNGAYGTNGARTGGTGGGAYACNYTN---TCNAGY CAYCCNGARCAYMGNATHYTNCARATGGTNCAYGGNYTNYTNACNTCNGGNGGNGARTTY TTYCCNGCNATHGTNGARAAYCCNTAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TGYCARACNGARCARGAYATHGARYTNYTNAAYGARMGNAARGAR ATHATHYTNMGNMGNATHMGNTCNCARGCNMGNAGYAAY---------------GAYAGY ATHAGYTCNTCNCCNCCNCCNMGNACNTCNACNCCNYTNCCNAARGTNAARATHGGNTCN GARAGYAGYAGYACNACNCCNGARCCNGTNAGYMGNGARGGNACNGTNTTYACNCCNTCN GCNGAYAARGARYTNGARGCNATHYTNAAYCAR---GAYGARGAYGCNAGYGTNAGYGGN TCNACNAGYGGNAARTCNMGNCCNGTNACNGAYGGNTCNYTNGARYTNGARGCNGARGAR AAYAGYGARGARAAYGTNAARGARGARGARGAYGARAAYATGAARGTNATHTCNMGNATH ACNGTNACNAARGCNGAYGAYAAYGARGAR---------------------ACNGGNAAR AGYAGYAAYAAYCARGTNGARAARCARCARYTNATHATHCCNMGNAGYCARGCNGGNTTY YTNACNCCNATGGGNTCNGTNGGNGAYTTYAARGGNTCNMGNYTNACNGTNAGYCARTTY TCNGGNAARMGNTCNATHATGAGYMGNGAYAGYATGMGNGARMGNGARAARATGAAYGCN GARGTNAAYACNATHTAYGCNGAYYTNAAYGCNMGNTAYGARGAYATGATHCARCAYYTN GCNAARATHGAYAARGGNYTNAAYACNAARGGNTCNTCNGCNGARTCNAGYGCNGTNGAY AGYYTNAAYGTNTCNATHGTNGGNCCNAAYCAYATHGCNMGNYTNAGYCAYCARGARATH GTNGAYACNATHAARGARYTNGARCAYATHCARTCNGCNMGNCARGAYAARAAYTGYCAR GCNGAR---------YTNGCNGARGGNATHAAYAAYCCNAGYGAYCARGGNAARGTNGAY GARGARGGNGARGARGARGTNACNGTNGAYGGNGARAGYGARGCNGTNGAYGAYCCNAAY ACNGARTGGAARTCNTTYGTNGARACNYTNTCNCARGAYAAYACNGARGAYAAYGARACN ACNTAYCCNTTYTGYGARGARAAYGGNATHTCNYTNYTNAGYACNGARGGNAAYACNGAY GTNCARAGYTCNCARGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNTCNGTNATGATGCCNATHACNAGYYTNGCNAAYGAR ATGGTNGAYTCNTGYGTNYTNATGCAYAARGAYTTYYTNTAYATGCCNGAYYTNATHGAR GCNACNTAYMGNTCNCAYACNGCNTGYAGYGTNGGNAARMGNTCNGTNAAYAAYGARACN TAYTAYCARATHGGNYTNCCNMGNGGNGGNAAYCCNGGNGARMGNACNTTYCAYYTNGAR AARGARGCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TTYAAYATHMGNCCNGTNAARGARGARTGYGGNCARGTNATHCARATG ATHAAYGARYTNGCNGAYTTYGARGARATGGCNGGNMGNAAYGARAAYACNCCNGAYGGN YTNMGNCARGAYATHTTYGAYGARCCNAARMGNTGYTCNTGYYTNGTNGTNGARAAYGTN CARAAYAARGARYTNGGNYTNATHGGNTAYGCNATHTAYTTYCCNGCNTAYTCNACNTGG GARMGNACNATHYTNCAYYTNGARGAYYTNTAYGTNAARCCNGARTTYMGNAGYAARGGN ATHGGNAARMGNYTNTAYCARGCNGTNACNCARATHGGNATHGAYATGGGNGTNGCNMGN YTNGARYTNGAYGTNYTNCARTGGAAYAARAARGCNAARGAYTTYTAYGARAARATHGGN AAYGTNGAYATHACNGARAARGARTCNTGGCAYMGNATGMGNYTNMGNAARGARCAYATG AARAARTTYGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CAYCARTCNCCNMGNCCNTTYACNTCNTCN GTNGCNCCNCCNCCNTCNAAYACNYTNYTNCARCARCARACNGARAAYATHTCNCARYTN GARAARCARYTNGARAARGARMGNGARGARAAYMGNMGNYTNAARCARGARATGGARGAR AARGAYAARAARATHGCNGARYTNGARAARTCNGTNGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYGGNTCNTGYGGNCAYTAYGTNGCNGAYGGNGAYGGNAAY GTNAAYACNTTYCARGAYAARAGYCAYGGNGGNACNTTYGAYGGNGTNGARCCNATGGGN YTNTTYTGGAGYATHAARTCNTCNCCNGGNYTNAARCCNACNMGNATHYTNAARTCNGAY YTNACNAAYCCNTAYCAYGTNMGNATHGCNGTNCAYCARGGNTTYGTNGAYTTYAAYGAR YTNCCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GCNTAY MGNGGNATHCCNTTYGCNYTNCCNCCNGTNGGNCCNYTNMGNTTYGARMGNCCNGARCCN CARCCNAARYTNGARGGNGTNTAYGAYGCNACNAARGARGGNCCNATHAGYATHCARCCN TGYGGNATHMGNATGGGNCCNAARCARCARGARGAYTGYYTNTAYYTNAAYGTNTTYATH CCNGTNCCNACNTCNGTNGCNACNACNAARACNYTNAARAARGTNYTNGTNTTYATHCAY GGNGGNGGNTTYTTYATHGGNTGYGCNAAYCARCAYGTNCCNGGNGAYYTNGTNGCNCAR GGNAAYGTNATHGTNGTNACNTTYAAYTAYMGNYTNTCNTGGYTNGGNTTYYTNAARGGN CCNACNGAYGARGTNAARGGNAAYATGGGNYTNTGGGAYCARYTNGARGCNYTNAARTGG GTNAAYAARAAYATHTGYGCNTTYGGNGGNGAYCCNAARAGYGTNACNYTNATGGGNCAR TCNATGGGNGGNGARAGYGTNTCNGGNYTNAGYATHATGAARCARGCNAARGAYYTNTTY ACNAARGGNATHATHATGAGYGGNACNATGTTYACNTGYMGNTCNACNGTNGGNTCNTCN GAYGTNYTNYTNGAYTGGYTNATHGAYAARACNGGNYTNTCNTAYTCNGAR--------- ---YTNATHCARGARYTNMGNAAYYTNCCNGARGARMGNTTYATHYTNCCNAGYCARAAY GARATHACNAAYAARTTYACNACNATHGAYGGNGARYTNTTYCCNGCNTCNTTYTCNGTN ATGAARCARGAYGARGARTAYYTNACNMGNGTNGGNTTYTAYGAYMGNGAYTAYYTNGTN ACNYTNACNAAYAAYGARGGNCARYTNGTNTCNACNGGNCCNTTY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNYTNACNYTNGGNGAYMGNMGNGTNGTNGAYGAYAARMGNATHAGY ATHGARMGNCCNGAYATHAARGAYTGGAAYYTNCAYATHMGNGAYGTNAARAGYAGYGAY CARGGNGARTAYACNTGYCARATHAAYACNAAYCCNGTNACNACNAARAARGTNTTYYTN CAYATHCCNGTNAARAARAARGTNYTNGAYGAYCARACNGTNAAYATHACNGTNAARGAR ACNATGACNGCNGTNYTNCCNTGYAARGGNYTNGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNAARCARGAYYTNGAR ATGAARGTNAAYTGGGCNGCNTCNCCNAGYACNGCNCCNAARCARGAYACNAGYAARCAY TTYCAYGTNTTYGTNGGNGAYYTNAGYTCNGAYATHGARCARCAYCARYTNMGNGAYGCN TTYGCNGCNTAYGGNGARATHTCNGAYTGYAARATHATHMGNGAYCCNGCNACNATGAAR TCNMGNGGNTAYGGNTTYGTNTCNTTYGTNAAYAARCARGARGCNGARTTYGCNATHAGY AGYATGAAYAAYCARTGGYTNGGNACNMGNCCNATHMGNACNAAYTGGGCNACNMGNAAR CCNYTNGCNCCNGTNGCNAARGARAAYGCNAARCCNYTNGCNTAYGAYGARGTNTTYAGY CARTCNAGYTCNACNAAYTGYACNGTNTAYTGYGGNGGNGTNGCNAAYGGNYTNACNGAR GARGTNATGMGNAARACNTTYGCNCARTTYGGNACNATHCARGARGTNMGNGTNTTYAAR GAYAARGGNTAYGCNTTYATHMGNTTYAGYACNAARGARGCNGCNACNCARGCNATHTGY GGNGTNCAYGGNTCNGCNGTNAAYGAYCARGTNGTNAARTGYTCNTGGGGNAARGARTCN AAYGARTCNAGYCARACNAGYCARCARTCNAAYAGYCCNCCNGTNGTNATGGTNCCNTCN CARCARCARCARCCNATHGCNGCNAGYCCNGCNGCNGCNCCNTAYGGNCAYCARTTYTAY AAYATGAAYTAYTAYCAYGGNGCNCCNTAYGCNGCNGGNACNCCNGCNTAYCARAGYACN GTNCCNACNCARGGNCARTTYATHCCNGCNTCN---GGNCARTGGCCN---AGYTAYTCN ACNTAYCARGCNTAYGGNAGYATGAAYGTNCCNGTNGGNGGNTAYGCNGGNYTNCARATG CARCCNGGNAGYCARCARCARCARTTYACNGGNCARACNCARGGNATGGTNGGNTAYCCN ATGCARCARGGNATGTCNMGNTCNAAYGTNMGNTAYGARGTNYTNCCNTCNGARGARCAR AGYGTNGCNGCNGARCCNGTNGARATGGCNATGGTNGTNCCNCCNCCNGGNTAYTCNGAR ACNGCNGTNATGGARCARAAYGGNGAYGAYCCNGCNTTYGGNCCNGCNAARYTNCCNAAY TAYGARGARGCNACNACNYTNCCNACNTAYGARGARGCNGARMGNACNAARYTNGARCAR GAYACNTCNGGNGGNAAYGCN---AAYGAYTGYGARTCNGGNMGNYTNACNTCNYTNGAY GGNATHAAYGARACNAAYATHGGNACNGAYGGNATGTTYATHTGYACNTTYTTYATHTCN TTYYTNTTYAAYTGGYTNGGNTTYYTNYTNTCNYTNTGYYTNTCNAAYACNATHGCNGGN MGNTGYGGNGCNYTNTCNGGNYTNGGNYTNTCNATHGTNAARTGGGTNGTNATHGCNAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TTYACNTCNCARACN TGGATHGARATHCARTCNATHTTYCAYGTNGCNAAYTGGGGNTGGMGNGCNGTNGCNATH GAYYTNCCNGGNTAYGGNCARACNAARGAYACNATHCCNGTNAARTAYTAYTCNGARTTY YTNTCNTCNGTNATHACNAARYTNGGNYTNAARMGNCCNATHATHGTNTCNCCNTCNATG AGYGGNYTNTTYTCNYTNCCNTTYYTNTTYGGNCAYGGNGTNGARAGYYTNGAYMGNGCN ACNGCNTAYGTNCCNGTNGCNCCNGTNAGYACNAGYCARTTYGTNAARTGYTAYTCNGAR AGYCARYTNCCNACNATGATHGTNTAYGGNACNAARGAYGTNMGNATHGGNGCNATHAGY AAYAARGAYYTNGGNCAYYTNCCNMGNGGNCARTAYGCNCCNATHGARGAYGCNGGNCAY GCNTGYTAYATGAAYAAYCCNGARGCNTTYCAYAARTAYYTNTAYTAYTTYYTNAAYAAR YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNGAYATGTCNAAYMGNGAYCCNAAYAAYYTNAAYGAYCAYGTNAAR GTNGCNTTYGAYGARGTNATHGGNGARCCNGAYGGNGCNCAYTCNATHGAYTGYGTNTGG ACNAAYTCNTAYAARTGYTTYAGYTGYTGGAARTCNTGYTGYTAYAAYYTNYTNACNATH TTYTGYGCNATHCCNATHTCNATGTGYTGGGGNTGYGARTTYGCNTAYATHACNTTYACN CAYGTNTGGCARATHACNCCNTGYATGMGNGCNTAYATGATHCARTGYGGNTGYATGCAR AARTTYTAYGGNACNTGYYTNCARTGYTGYATGCARCCNTGYTTYGARGCNATGGGNTTY ATHYTNAAYAAYATHAARGTNACNAAYGTNAGY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ACN MGNMGNCAYAARAGYTGGGGNAGYGAYYTNGAYACNACNTAYAAYACNACNTTYGTNTCN AARGGNAGYCAYACNGAYYTNTCNMGNYTNACNCARTCNGTNGGNAGYCCNCARMGNGAY TTYACNAGYACNAGYGGNGAYATHCAYAGYGCNYTNCCNGAYACNAARGARYTNTGYMGN MGNYTNGARGAYAARATHAAYAGYYTNACNMGNATGGGNGGNAAYYTNCARAARGARAAY MGNGARATGGCNAGYYTNATHGAYMGNCARGGNGARAARYTNGAYACNGTNAARYTNATH GARCARAARACNMGNGGNTCNMGN------GCNTCNCARGARAGYTAYATH---CARAAY ---TCNTTYGARACNATGAARAARATGGAY------------------------------ ------------------ATGATHMGNTCNCARYTNGARTTYCAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CARTCNGCNATHTCNMGNAGYYTNCAR CAYYTNGAYGARGTNCARGAYCARYTNTCNACNYTNCARCAY------------------ ------------------ATGAAYAARCCNGGNGAYCAYGTNATHYTNTTYCAYTGYTCN CARTTYCARYTNAARATHGGNYTNCCNGGNGTNGCNGTNAAYCARGAYGCNGTNGCNAAR CARGTNYTNCARGCNAARGARMGNGCNGAYCAYATHYTNGGNAARGCNATGGAYGTNYTN AARGCNAARGARATHGTNGGNTAYTCNATHATGGGNAGYGGNGAYAARCCNCAYAAYGTN ATHYTNCARACNGCNACNGCNGARAARGTNGAYCAYATHGTNGTNGGNACNMGNGAYYTN GGNGCNATHAARMGNGCNTTYYTNGGNAGYGTNAGYACNGARGTNGTNMGNAAYGCNACN GTNCCNGTNACNATHGTNAAR---------ATGGAYACNYTNTCNYTNGTNGAYAARGTN GCNATHATHACNGGNGGNAGYTCNGGNATGGGNGARGCNACNGCNATHYTNTTYGTNMGN MGNGGNGCNAARGTNACNATHAAYGGNMGNAAYATGGAYMGNYTNAARGCNGTNGCNGAR AARTGYAARAARGCNTGYGGNAARAGYGAYMGNGTNYTNATHGTNGCNGGNGAYYTNACN ACNGARAGYTGYMGNCARGAYATHGTNGAYAARACNGTNGAYCAYTTYGGNMGNYTNGAY GTNYTNGTNAAYAAYGCNGGNGCNYTNGCNGCNGARCCNYTNMGNAAYATHACNGARGCN GGNATHGAYGCNATGATGGAYYTNATGTTYAARGCNCCNATHTTYYTNTCNAARTTYGCN YTNCCNCAYYTNAARAARTCNCARGGNAAYATHGTNAAYGTNTCNACNACNATHACNACN GARAAYATGCCNAAYTTYTTYTCNTAYGCN---ACNAARGCNGCNYTNGAYACNTTYACN GARTAYGCNGCNYTNGARTTYMGNCARGTNGGNATHMGNGTNAAYTCNGTNAARCCNGGN ATHACNGARACNGCNATHTTYGAY---------GGNGGNGAYAARGARAARGTNMGNGGN TTYYTNGAYGGNCARAARAAYCAYACNATGCARGGNMGNAAYGGNCARCCNGARGAYATG GCNGARATGATHGCNTTYYTNGCNTCNGAYGCNGCNAGYCAYGTNACNGCNCARTAYATG AARGTNGAYGGNGGNMGNAGYAARTAYTTYCAYCAYGGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARTTYGTNGAY TGYYTNATGAARAARGAYTAYCCNAAYGCNAGYAARYTNTGYAARATGATHYTNYTNTTY GARCCNGARAAYGARGARGCNYTNAARTTYCARCCNYTNATHGARGARAARATGMGNYTN GAYGCNGARGCNGARGARGARGARGGNAGYAGYGAYGARGAYGAYGAYGAYGAYAGYGAY GAYAGYGAYGARGAYTCN---AGYMGNATHGTNTGGGTNGAYYTNGARATGACNGGNYTN GAYGTNGARAAYGAYCARATHYTNGARATHGCNTGYYTNATHACNGARAARGAYYTNAAR CCNGTNGCNGARGGNCCNAAYYTNGTNATHCAYCARAGYGAYAGYGTNYTNGAYGGNATG AAYGARTGGTGYGTNAARCAYCAYGGNGARTCNGGNYTNACNGARGCNTCNMGNAAYTCN AARATHGAYATHATHGARGCNGARAARATHGTNYTNGARTTYGTNCARCARCAYACNTCN AARGGNAARTGYCCNATHGGNGGNAAYTCNGTNGGNACNGAYAARCARTTYATHATHAAR AAYATGCCNGGNYTNGCNGARCAYYTNCAYTAYMGNATHATHGAYGTNAGYACNGTNAAR GARYTNTGYMGN---------------------------------MGNTGGTAYCCNGAY GARTTY---AARACNGCNGCNAARAARYTNCAYCAYMGNGCNATGGAYGAYATHAARGAR AGYATHGARGARYTNMGNTAYTAYMGNCARGGNATHTTYAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARATHATHMGN AAYTAYCARTAYMGNTGGYTNATGMGNCARAAYATHCCNTTYAARACNACNGGNCARGTN YTNATHYTNTTYATHATHTAYACNACNTTYTGYGAYACNTTYTCNCARACNAAYTTYCAR YTNAARCCNYTNGARYTNGTNTTYGTNGCNGTNYTNATHYTNTGYYTNCARGTNYTNTTY ATGGTNTTYYTNYTNTTYTCNAGYTCNTTYAAYTTYACNTCNMGNGAYGTNATHACNATH GTNTAYTGYGGNACNCAYAARTCNYTNACNYTNGGNATHCCNGTNATHGARATHATHTTY GARGGNTCNCCNAAYYTNAGYTTYYTNACNATHCCNYTNYTNATHTAYAAYCCNGCNCAR ATHGTNTTYGGNGCNATHTAYATHGGNATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CCNGARAARATHMGNGGNGGNGGNGARGCNTTYAARTTYCCNTGGACNGCNTAY TCNAARGCNCARCARTTYCCNTTYAARTTYTAYTGGAARTAYGGNMGNYTNTTYMGNTAY TTYTTYTAYACNTCNGCNATHATGTTYCCNYTNATGGTNAARYTNACNAARGCNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNGCNGTNCCNAARATGMGNMGNACNYTNGARGGNGTNMGN GGNCAYCCNTAYACNMGNGTNTCNYTNTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------- >frydis TTYYTNATHGCNCCNYTNATHGTNGGNGTNGTNTTYGGNMGNTAYGAYCCNTAYAAYGAY ATGGCNCARTAYTAYCARATGCARYTNYTNGCNGAYGTNYTNGAYGARTAYYTNCCNGAR AAYTTYCARYTNGAYAAYAAYGAYAAYGAYATHGCNATHMGNTCNTAYTGGCCNGARYTN GCNGCNTCNYTNGARGAYGAYAGYGCNAARTCNCCNGAYGAY---------ATGTAYGGN AAYGARATGTAYAGYGGNGCNCAYATHMGNGAYCARGARCAYATHGARCAYAGYGCNYTN CAYGGNTAYCARTCNGTNGCNGGNGGNACNGCNGARGGNCCNAARAAY---AARTTYCAR AARAGYGAYAARCCNYTNCCNGCNTAYTGYAAYCCNCCNAAYCCNTGYCCNYTNGGNAAR ACN------GARAAYTGYGTNGARGAYTTYGARAAYTCNGCNGARAAYAAYAARAARYTN YTNAGYGARCARGAYTGYCCNTGYGAYACNGARCAYATGTTYAGYTGYCCNGCNGGNMGN GARACNGTNTCNTCNAARGGNCARACNGGNTAYCARCARACNYTNAAYAARGTNYTNAAY CARYTNTCNAARTCNGGNGTNGAYATGGAR------GARGGNGAYGGNGCNATHAGYCCN GCNMGNAARMGNGTNACNYTNGTNGCNAARAARTCNCCNCAYATHATHCAYAARMGNGCN GARAAR------ATHATGAAYCCNTAYTTYGCNGGNACNAARATGGAYATHGCNGCNAAR AARAAYCAYCARYTNGCNCARAGYGTNATGTAYYTNACNACNGGNCAYCCNTAYGTNATG TTYAAYAGYGTNACNTGYGCNATHTCNGCNTAYATHGCNATHGARMGNTGYATHTGYGTN GTNTTYCCNTTYAARGTNAARACNYTNTTYTCNCCNGGNMGNTCNYTNATHATHGTNTGY GGNATHTTYYTNTAYTAYGCNYTNTGYMGNYTNCCNGTNTTYYTNACNYTNMGNYTNGGN TGG--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARAARMGNCARYTNGTNGCNYTNCAYCARCARCAYATHCARGCNATHYTNAAYGAR MGNAARMGNGARGCNATGGAYAAYTAYATGNNNGCNYTNGARACNGGNGARGTNGAYAAR ATHACNAARTAYYTNCAYAAYTAYATHAARGCNGARGARAARGAYMGNATGCAYACNGTN AAYCAYTTYGARCAYATHMGNTAYGCNGCNCCNAARGARGCNYTNMGNATHCAYMGNCAY ATHATHAAYCAYYTNAARYTNTCNGARYTNMGNATHGAYCARGCNYTNGAYATGYTNACN CAYTAYCCNGCNGTNGARGCNCARGTNMGNCCNGARATHGARGARTTYATGAARAGYTTY AAYGCNATHGCNACNAGYATHAARAAYGTNGTNYTNCCNGTNCCNGTNGTNGARGARGAY AGYGAR---GARGAYGARAGYAGYGAYAGYGAYGARGAYATHGAYGAYAGYACNGGN--- ------AAYATHGAYATHGAYGAYAGYACNGARTTYGAYTCNAGYAGYGARGARGTNCAR ACNGAR---------------------------------------GGN---------CAY GCNGAYACNAAYAAYGTNGTNATHGAYGAYGARGTNGARGARAAYGARCAYAGYTAYGAR ATGAAYCAYCAYTTYTCNGCNAAYGCNAARGCNGAYACNCAYAAYGTNMGNCAYGGNYTN CARAAYTCNGCNACNGCNAGYACNGCNATHGGNAGYACNGTNGGNATHGCNYTNGGNAGY GTNAGYGTNTTYGTNATHATHGTNGTNGCNGTNATGATGATHCAYMGNAAYMGNAAYMGN CARTCNGTNGCNCAYGGNTAYGTNGARGTNGAYCCNTCNGCNACNCCNGARGARMGNCAY YTNGCNAAYATGCARATGAAYGGNTAYGARAAYCCNACNTAYAARTAYTTYGARGAYACN CCNAARGAYAARYTNTAYAARCARATHACNGTNGARGTNAARGGNCAYGAYCCNGCNGTN YTNAAYAGYTAYCARAARTTYACNACNACNGCNGCNGARCAYYTNGGNGTNCARATHGCN AAYATHTCNACNCCNCCNAARGTNATHACNMGNAARAGYYTNYTNAARTCNGTNTTYATH TTYAARAARCAYCARCAYCARTAYGARACNMGNACNYTNTTYMGNATHTTYGARYTNAAR CAYYTNACNGARTCNACNGCNYTNACNTTYYTNGARTAYATH------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GTNCAYAAYYTNGGNATHGAYGARGCNTGGATHCCNAGYGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNTAYTAYACNAARCARACNATHGGNAAYGCN TGYGGNACNATHGCNATHGTNCAYGCNYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TAYGARGCNGARMGNGAYAARTTYGTNMGNGARGARTTYGCNYTNMGNYTN GGNGCNGGNYTNACNATGAAYTAYAARGARGCNATGGTNAGYGARAARATGATGACNYTN AARMGNGCNYTNGCNGAYMGNAGYMGNCARACNTCNTAYCCNTAYCCNCCNTCNGTNCAY TTYTTYAARGTNAARCARGARATHGGNMGNTCNGARATHTTYCARATGATHCARAARATG CCNAARGGNGGNGCNYTNCAYTAYCAYGCNGARGGNATGACNTCNATGAAYTGGYTNATH CAYAAYATHACNTAYGAYCCNACNYTNTAY---------TCNMGNTAYGAYGARTCNGGN ACNMGNCARTTYYTNTTYMGNGAYGARGCNCCNGGNGGNGGNTAYMGNAGYGTNGARMGN GARMGNAAYAGYTAYGCNATHCCNAGYATGTAYGAYGAYMGNYTNATHGCNGAYYTNAGY TGGACNGAYGARGAYCCNGCNGTNMGNTAYCCNTCNATHAAYGAYGTNTGGGCNAARTAY CAYCARTTYTTYMGNTCNMGNACNAGYYTNYTNGCNGAYCCNGAYMGNGARATHMGNTAY ATHATGCARGGNATHTAYGARGCNTAYCARGAYGGNYTNCARTAYYTNGARYTNMGN--- ---------------------------YTNGCNCCNMGNAGYGARGARTTYTTYGAYAAR YTNYTNGTNGARGTN---GAYAARTTYAARGCNGTNCAYCCNAGYTTYATHGGNATHAAR ATHATHATHGCNAARATHMGNTTYATHCCNGTNGCNGAYCARYTNGARTGGGTNAARTCN GCNYTNAAYYTNMGNAARAARTTYCCNAAYYTNATHAARGGNTTYGAYYTNGTNGGNCAR GARGAYACNGGNGGNACNYTNYTNTAYTAYATHGARGCNYTNYTNTAYCCNACNGARCAY GARAAYACN---ACNYTNCCNTTYTTYYTNAAYGCNGGNGARACNGAYTGGACNCAYGCN ---ACNGAYATGAAYYTNATHGAYGCNATHYTNYTNAAYACNACNMGNATHGGNAAYGGN YTNGCNGCNYTNAARCAYCCNAARGTNATGGAYGCNATHMGNAARMGNGGNATHGTNATH GARYTNAAYCCNGTNTCNAAYCARGTNYTNGGNYTNGTNTCNGAYYTNMGNAAYCAYCCN GGNACNATHYTNTTYGCNAAYAAYGAYMGNGTNGTNGTNTCNTCNGAYGTNCCNCAYYTN TGGAAYGCNTGYCCNATGTCNCAYGAYTTYTAYATGGCNTTYATGGCNYTNGGNGGNGTN GGNGAYGAYYTNMGNYTNYTNAARCARYTNGCNATHAAYTCNATHATGTAYAGYACNATG AGYGAYACNGARAARGARCAYGCNATGGCNAARTGGCARACNMGNTGGGAYGCNTAYATH GAYGAYATGGTNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARMGNAAYATHAAYATGYTNMGNYTNGGNAAR MGNCAYYTNAAYATGYTNMGNYTNGGNAARMGNCARYTNAAYATGYTNMGNYTNGGNAAR MGNCARYTNAAYATGYTNMGNYTNGGNAARMGNCARYTNAAYATGYTNMGNYTNGGNAAR AARTCNGAYGAY---AGYGARAARMGNMGNYTNAAYATGYTNMGNYTNGGNAARMGNTGY CCNTCNTTYACNTCNTGYCCNAARGARGCNGCNGARAGYTTYTGGGGNGCNGCNTCNAAR ACNTTYGCNAGYCARGCNAARGGNGARGTNACNATHATGYTNGAYGGNTCNAAYCCNACN GCNTAYMGNAARGAYAGYTTYTTYGCNAARTAYGARYTNCCNAAYYTNAAYGTNMGNGTN CCNTCNYTNAAYGTNYTNYTNGTNCAYAGYYTNTCNGARCCNGTNMGNGARAGYTGYGGN ACNGGNAGYYTNGTNCARYTNGCNTCNGCNGTNAARGCNMGNGGNYTNAARTTYACNTGY CARGAYAAYCCNACNGCNGTNYTNTAYYTNYTNTGYGCNGAYGAYCCNCARAGYACNCAY TGYGAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARYTNTGGAAYAARGTNCARGARGARACN CARAARGAYGAYMGNGAYYTNYTNYTNTCNGTNYTNTCNTAYYTNGARCCNGGNTAYAAR TGGTCNTTYTAYGCNCAYCARATGACNACNYTNCARYTNTAYGTNCAYYTNACNGARGTN YTNAARCARYTNGARCCNGAYGARATGMGNGCNGTNYTNCAYATGYTNCCNMGNGCNATH CARGARCARYTNGARYTNGTNATH------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNCCNACNMGNACNGCNGAYGAYATHYTNCARGAYTCNTCNGGNYTNGTN YTNGAYAARMGNCCNAARTAYATGGAYACNMGNMGNGAYYTNGAYGTNTTYAARGAYYTN GTNYTNATGAGYATHCARGARYTNGTNGAYGARGGNMGNYTNGAYTCNGTNGTNYTNTCN GARGAYGARMGNGAY------TCNGGNAARACNGTNGARAARMGNMGNTAYATGGGNYTN TGYATGCAYMGNCARGCNAAYCARTTYATHCCNTTYCCNTGYYTNMGNGCNGGNMGN--- ATGAARYTNATHATHYTNYTNGTNATHGTNGGNGCNGCNGTNTTYGCNGAYAAYTAYYTN TGY---CCNAAYGARGGNGARAARTTYGARTGYTAYGARTCNAARTCNGAYYTNMGNACN TGYATHACNAAYGGNMGN------MGNGARAGYGTNATHTGYTCNAARTGYAARAARAAR TGGGARTTYTGY------AARACNAARTTYCARAGYTCNGAYTAYCCNGAYMGNGAYTGY GGNGCNGAYTAYGARAGYACNGARTGYACNAARGCNAAYTCNGARGTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GGNTTYYTNAARGAYYTN ATGGAYGARATHTCNMGNAARGCNAARTTYACNTAYGAYTTYCARGAYTCNYTNGAYGAY AARTAYGGN---CARYTNATHTCNGGNTGGTCNGGNATHATGGGNGAYGTNGTNAGYGGN MGNGCNGAYGTNGGNGGNGGNYTNGTNGTNACNGCNACNMGNGARGAYAGYGTNGAYTTY ACNCARCCNTAYYTNTCNAAYGGNGTNAAYYTNYTNGTNMGNAARCCNTCNTGGTAYGAY YTNGGNYTNGGNTAYYTNGTNMGNCCNYTNTCNTCNGAYTAYTGGATHATGYTNYTNGTN GTNYTNYTNYTNATHGGNATHGTNTTYTTYATHATHGGNAARTTYAGYCCNTAYGARTGG GGNAAYGTNGCNGCNGAYMGNGAYCCNMGNGGNGCNAARAAYAGYTTYACNYTNMGNAAY AGYTAYYTNTTYGCNYTNACNACNYTNTCNTGGCARGGNTTYMGNGARGCNCCNAARTCN YTNTCNGGNMGNATHATGGCNGCNTTYTGGYTNYTNTTYGTNYTNTTYACNYTNATHGCN TAYACNGCNAAYYTNACNGCNTAYTTYATGGCNCARATHCCNGAYYTNAARTTYACNACN TAYGARGARYTNYTNYTNGARGAYGAYGTNGGNGTNTAYGCNYTNCARTCNGGNTCNACN GARGARTAYYTNMGNACNAGYMGNAGYAARACNYTNCARAGYYTNTGGTCNAARATGAAY GAYGARGGNACNTTYGCNMGNTCNGARATHGARGGNATHGCNMGNGTNAARTCNAARGGN AARGAYAAYGTNTTYTTYATGGARTCNAARAARGCNGCNTAYGARGCNGCNCAYGARGAY TGYGARYTNATGGTNTAYGGNGARACNYTNTTYCCNAGYGCNACNGCNTTYGCNGTNGCN MGNGGNTCNGTNTTYAARAARAARATHAGYGAYGCNATHGARCAYYTNMGNGTNATGGGN TAYYTNGAYCARYTNGARAARAARTAYTGGGAYTTYGAYGTNCARTGY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNTGYYTNTTYGCNGGNACNACNTAYGCNGTN TTYTAYATHCCNGGNTCNGTNGTNAGYTAYCCNAARATGGGNAARMGNGCNTTYTAYACN AAYGCNACNGGNAAYMGNTAYCCNYTNATGGGNMGNMGNTCNTCNCCNTCNGAYAARMGN GARGCNGAR---------CCNCARGARCCNGCNGTNAAYGCNATGGTNGARGARGGNAAY GARTAYAAYAARMGNGGNGTNTTYACNCARGGNCCNCAYMGNAGYTTYCCNMGNGTNGGN MGNACNAAYGCNGTNGGNGGNMGNATHMGNAGYGARTTYYTNAARAGYYTNGCNGARMGN YTNAAYMGNAAYGTNGARGGN---GGNGARGGNAAYGAYGTNMGNAGYYTNYTNGGNGGN CARGGNGARAARTCNGTNGARGAYAAYTCNTAYAGYTCN---CARYTNYTNTTYYTNATH TTYGAYGARGAYGGNGAYAGYCARYTNAGYAARTCNGARTTYTAYGCNGGNGCNACNAAR ATHATGGARCARAAYYTNYTNTGY------------------------------------ CCNGTNGARGTNAARATHGGNYTNAAYYTNATHGAYATHAARGARATHAGYMGNYTNMGN AAYGARGTNGARATHGAYGCNTGGATHACNYTNAGYTGGAARAGYGGNATHMGNTGGTCN CCNTCNMGNTTYTAYAAYYTNAGYGAYGTNMGNYTNCCNGTNTCNCARATHTGGGTNCCN GAYATGGCNGTNTAYAAYGGNGARATHAGYTAYYTNGARACNATGAGYCAYGGNCARGCN GTNTTYTTYCAYGAYGGNTCNGCNYTNTGGATHCCNCARTGYMGNYTNMGNGTNATGTGY GAYYTNAGYGAYGAYGTNGTNYTNACNAAYGCNACNTGYTCNATHAARATHGGNTCNTGG ACNTAYAAYGGNCAYCARATHTCNTTYGAY---GAYGGNCCNACNTTYGAYYTNAAYGAY TAYTTYGCNGGNTCNAAYTAYAAYATHYTNGGNGCNTCNGCNAARGTNGARGTNAARCAY TAYCCNTGYTGYCCNGARCCNTAYCCNAAYGTNYTNTTYACNTTYTCNTTYAAYMGNAAR AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GCNAAYYTNGARCAYGTNTGYAAY--- CCNCAYTTYGARATGCARCARATGGGNATHTGYGGNGAYMGNYTNGTNACNACNGTNCAR TAYATHTGYCARTTYGCNATHAGYACNGCNMGNTAYYTNGTNAARMGNAGYTAYCCNMGN GAY---------ATHGAYMGNGGN---ATHCARGAYATHATGYTNAARAARAARGAYGCN YTNTCNTAYYTNTCNAARMGNTCNGGNTCNCARGGNATHATHTGYGARTGYTGYATHAAY TCNTGYACNATGAAYGARYTNGTNCARTAYTGYGARCCNCCNAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR MGNGGNCCNCCNMGNTTYGTNGGNAARMGNGGNGTNCCNMGNTTYGTNGGNAARMGNTAY MGNCCNMGNTTYGTNGGNMGNMGNGGNGCNCCNMGNTTYGTNGGNAARMGNAARGTNCCN MGNTTYGTNGGNAARMGNGAYAAYGAY------ATHGAYGCNGAYGAYTAYATHTTYCAR TGGGARGCNTTYAAYGAYGTNTAYGAY------------AARMGNGAYGCNCCNMGNTTY GTNGGNAARAARMGNATHCAYGAYAARAARATHMGNGAY---------YTNYTNAGYGAY TGGAGYMGNGCNATHGCNATHCARCAR---------MGNATHGAYAAYGAYAARMGNTGG ACNAGYCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARMGNMGNGAR GCNATHGCNAAYACNMGNTCNTTYATGGGNGGNMGNTCNCARAAYTCNAGYMGNGAYAAY AGYTGGAAYMGNGAYGAYMGNMGNCARTTYATGGGNCCNMGNAGYTCNGGNGARMGNGAY AAYCCNATGACNMGNAGYGAYAGYGGNGTNMGN---ATGGARGARTTYMGNGCNCCNGCN CCNCCN------GCNGTNAARCARATGACNGARACNGARATHGARACNAARGCNTCNACN ATHYTNGAYGARTAYYTNAAYATHMGNGAYYTNAGYGARGCNAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TGGAAYGTNYTNGAYGARYTNGAY GAYYTNTCN------GGNGAYCCNYTNGGNGAYGAYAGYATGGARGCNTTYGTNAAYYTN GAYAARTTYTTYAGYGGNAAYTCNTTYTTYGAYGARGARGGNAAYYTNATHGTNCCN--- GAYGARAARGTNGCNGARGTNMGNCCNGTNATHAAYTTYACNCARCCNCARACNTCNGCN GARGTNTCNGAYCCNACNCCNTCNCARCCNATHAARACN---------------ACNGAR AARCCNTCNMGNAARMGNTCNGCNMGN---------GGNGGNACNAARACNAGYYTNTAY GARATHCCNGCNGTNTCNATHATHCCNGAYATHGTNGARGAYGTNTCN------CARCAY YTNGCNATHGAYACNGARYTNGAYCAYGAYTAYAGYTCNAARMGNCARMGNATGTCNTCN GTNTCNGARATGGTNGCNTCNACNAGYGGNACNATGAARACNTCNACNCARGGNAARAAR GTNACNYTNACNCCNAGYGCNTCNGAYAGYAAYGAYYTNCCNATH--------------- ------------------AAYGARTCNATGGAYMGNCARACNACNMGNMGNATHAARAAY AAYCAYGCNTCNAARMGNTCNMGNGARCARMGNAARCARAARTTYGTNGAYATGGTNGCN GARGCNGARGARYTNGTNGTNAARAAYCARGARYTNMGNGARAARATHGTNMGNYTNGAR CARYTNGCNAARGARATGAARCARGTNYTNGTNGCNAARATGGCNGGN------------ ---------------------------------------------AAYCAYGAYTGYYTN YTNTGYCCNGGNAAYYTNGAYATHACNATGCCNGAYGAYTCNGGNCAYTCNATGGTNGTN GAYTTYYTNGCNCCNCCNACNCARGAYGGNTTYTAYTCNGCNGCNGCNGARTTYGTNGAR ACNTTYAARTCNGARAARATHMGNCCNCAYTGGGCNAARMGNTAYGAYAAYATHGAYGGN ATHATGCAYCAYATHCARAAYGTNTTYGGNTCNAAYYTNGARGARTTYAGYMGNCARAAR MGNYTNGCNGGNGTNGAYCCNTGYGAYATGTTYATGAAYAGYTAYYTNATHGCNATHTTY GGNMGNAAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CCNGAY ATHAAYAARAAYAAYMGNYTNAARGAYTCNTCNGGNGTNTCNAGYAGYTCNCARTCNTTY GTNTTYGGNMGNAAYYTNTCNCARMGNGTNACNGGNATHTCNTCN---TCNCCNGTNGAR AAYGARGCNTCNGCNTCNTCNGGNTTYGTNTTYGGNGARTCNATGAGYTCNMGNGCNACN GTNGARACNAAYGGNTCNTCNCARTCNCAYAARGAYGAYGARAGYGAYTCNGAYTCNGGN AAYAARYTNAAYCARACNYTNGARGARTCNGCNMGNGARTAYCARGCNAARCAYGARACN AARACNGARYTNAARGARGTNGARACNATHACNGGNGARGARGARGARTCNAAYGTNYTN CARGCNAAYGCNAARYTNTTYTTYTTYGARACNAGYAAYGARACNTGGATHGARMGNGGN MGNGGNACNATHMGNYTNAAYGAYATGTCNGCNMGNGAYAAYACNAAYTTYCARTCNMGN YTNGTNATG--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYGGNTAYAARYTNAAYGTNGAYAAYCCNCAYMGNCCNATG AARACNYTNACNGCNATHATGAAYTTYTTYGTNCARACNTCNGGNATHTTYACNACNGCN CCNATGACNTGYAAYAAYYTNCARAARATHGGNATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGCNTCNTCN AAYYTNTCNMGNACNGTNYTNAARTCNYTNAARGGNMGNCCNTTY---TCNGCNGCNGCN GCNCARGCNGAR---AARGCNCAYGTNGARACNGTNGAYAARTGYACNGTNAARAARYTN AAYAAYGGNYTNYTNGTNGGNACNGTNCCNTCNGCNTCNCCNATHGCNMGNYTNGCNGTN GTNGCNCAYGCNGGNTCNMGNTTYGARGAYGGNGAYAAYYTNGGNGTNTCNCAYTTYYTN MGNYTNTCNTCNMGNYTNMGNACNGARAAYATGTCNAGYYTNGCNGTNACNMGNACNGCN CARCARTTYGGNAGYGAYATHACNATHACNGGNACNMGNGARTAYATHTAYTTYAARAGY AAYGTNACNMGNGAYTGGGCNGAYCARATGGTNAARGTNYTNCARGARYTNACNACNAAY CARATGTGYGARCCNTGGGARGTNTCNGAYGTNCARAGYGAYGARGAYGGNATGYTNYTN GAYYTNGCNYTNTAYGAYACNMGNCCNCAYATHMGNGCNGTNGARYTNYTNCAYTCNGCN GCNTAYMGNACNGGNYTNGGNAAYTCNYTNTAYGCNCCNAGYCAYATHGTNGGNCARATH TCNCCNCARCARGTNATGCARTAYGTNAARGCNAAYTTYACNGCNGGNMGNATGGCNYTN ATHGGNGTNGGNGTNGAYCARGCNCARYTNGARGARTAYGCNTCNGAYTTYAARYTNCAY GAYGGNCARGGNGCNCCNGTNGARAARGCNACNTAYTTYGGNGGNGGNGARATHMGNAAR AAYATHGGNGGNGARGTNTCNTAYGTNGCNGTNGGNTTYGARGGNCCNAGYYTNACNAGY AARGAYYTNYTNGCNTCNGARGTNYTNMGNCAYATHATGGGNACNGGNCCNCAYATHAAR TAYAGYAAYGGNACNGCNACNGCNCARYTNACNAARGCNGTNGCNGARGCNACNAGYGGN CCNTTYTTYGTNTCNGCNCARAAYYTNACNTAYACNGAYAGYGGNYTNTTYGGNTTYAAY GCNGTNGCNCAYACNTCNCARGTNGARCARGTNGTNCARGCNGCNGCNAAYAARYTNAAR AGYYTNGGNTCNGGNAAYATHTCNGAYGARGAYGTNAAYMGNGGNAARCARCARYTNAAR GCNGARATHTGYATGCARTTYGARAAYCCNGAYGTNYTNYTNAAYTGGYTNGGNGARCAR GCNYTNAAYGGNTCNGARATHGTNACNCCNGARGAYGTNTGYAARATGGTNGAYAGYATH AARACNAAYGAYGTNAARACNGTNGCNAARACNATHGTNAGYTCNMGNCCNTCNATHGCN TCNGTNGGNAAYACNGCNAAYGTNCCNTAYYTNGAYAARYTN------------------ AARCARAARAGYAARAARAAYAARAARGGNGARGARGGNGARGCNACNGARGARGCNCAR GARCAR---------CARCCNGARGCNGGNGAYGCN---GCNGARCARAARGTNGARGAR AAYGGNAAYGCNGCNAARYTNGARGCNGGNGARAGYGAYGTNGARGCNGCNGCNGARTCN CCNGARCCNGCNAARGARGARGARAARCCNGARGARGCNCCNGCNTCNTCNGARCARGCN CCNGTNAGYGARGARCCNGCNTCNTCNGCNGCNATHGARGARGCNTCNGCNCCNGARCCN GTNAARGCNGAR------------GARCCNGCNCCNGTNGCNGCNGARGARAGYAARGAR GARGARAARGTNGCNGAR------------------------------------------ ------------------------------------GARAARAARGARCCNGARGAR--- CCNGCNAARGARGARGARCCNGTNGTNCARGARGARCCNGCNAARGARGARGARAARCCN GCNGARCCNGARCCNGAR------------------CCNGCNGCNCCNGTNGARGARTCN GCNGCN---------CCNGARCCNGARACNGCNGARCCNCCNCCNGCNGARGARGAR--- ------------------AARCCNGCNGARAARGTNCARACNAARGTNAARAARACNCCN AARYTNGCNCARACNGTNTAYGCNGCNMGNGGNATHYTN------AGYYTNTCNAARGAY AARGARGGNTCNATGGGNGGNAGYGARGARAGYGCNCCNGCNACNCCNTCNGARACNGCN GARACNGGNGCNGCN---------GAYGGNTCNGCNGCNGARACNGGNGARACNGCNGCN CCNAGYCARGARTCNGCNCCNTCNACNGTNMGNACNGARTTYAARTGGGARAAYGGNGGN GARACNGTNYTNGTNAGYGGNACNTTYAAYAGYTGGCARGARAARATHGCNYTNTCNAAR AAYGGNGAYGTNTTYACNGGNTTYATGGAYYTNCCNGTNGGNGARTAYYTNTGYAARTTY ATHGTNGAYGARGARTGGGTNGTNAAYAARAAYYTNCCNATHAARTCNGGNGARGAYGGN CARGARAAYAAYGTNATHYTNGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHYTNTAYTGGTAYTCNATHCCNGAYGTNTAYYTNTGGTAY ATHGAYACNAARCAYMGNACNTTYYTNTGGACNTTYTTYYTNYTNTGYCAYTTYGTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GCNAGY TAYATHCCNGGNYTNMGNTCNCARMGNGARTAYATHGTNACNCCNATGMGNAGYAGYGTN CCNTAYTTYTGGMGNATGGTNTGGGARCARMGNAGYGCNGTNATHGTNATGYTNTCNGAY YTNACNGARGAYAARACNMGNGTNAAYCCNTAYTGGCCNCARAAYATGAARAGYCCNGTN MGNTAYGGNGAYATHGTNGTNGARATGATHAAYYTNTCNAARYTNAAYAARTGYATHACN MGNGAYTTYAARATHTCNGTNAAYAARATGAGYMGNACNGTNACNCARGTNTTYATHCAR GCNTGGTGYGAYTTYGGNGTNAAYYTNTCNTTYGAYGAYGTNATHGARTTYYTNCAYYTN GTNMGNGGNAARATHACNGCNCARAAYTCNGGNCCNCCNGTNATHCARTGYAGYGCNGGN GTNGGNAARACNGGNACNTTYATHGCNYTNGAYTAYTTYYTNCARTAYATHGARGGNCAY AGYYTNGAYGAYACNATHAAYGTNTTYGAYTAYGTNYTNGARATGMGNAARAGYMGNCCN MGNATGGTNCARGCNGARACNCARTAYATHTTYATHTTYGAYGTNYTNGTNGARGTNATH MGNAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYYTNGARGARCARAARAGYGCNYTNAGYATHCAR GTNAARGARYTNAGYGARAAYTTYCARGAYGARAARGARGCNAAYAGYMGNYTNAARGAR AARAAYAARYTNATGAARGARGARYTNMGNCARGCNMGNGTNGCNYTNAARCARCARGAR GARYTNYTNCARCARGTNGCNACNACNTCNGARAARGCNGCNAARGARTAYGARGAYATG GARCARACNTAYMGNAARGARATHGTNGTNMGNAAYGARGCNGARMGNGTNGCNCARMGN YTNTTYACNGARMGNGAYCARGCNMGNMGNGARAGYGCNYTNGCNYTNAGYAARGTNGCN GAYAAYAARAARYTNATGGAYGCNATGYTNGARATHCARGARYTNAAYACNAARATHGCN CARAAYAARGARGAYTAYGAYMGNAARATHGGNGARYTNGARATHCARYTNAAYGCNGCN AARGARGTNTTYAAYCCNGARACNYTNGARTCNGARAAYGARGARYTNATHGARGARAAR AAYTCNYTNCARGTNAARYTNGARAARAGYGARTCNGARATHAARGARYTNYTNTCNAAR TAYACNGCNYTNATGGARTCNTAYAAYAARYTNGARACNAARTAYGARAGYGCNACNMGN CCNCCNCCNCCNCCNCCNCCNCCNGTNCCNCCNCCNYTNCCNACNACNAARTCNGGNGGN TTYYTNCARMGNATHGTNGGNMGNAARGGNCARMGNGARAARGCNAARGARCAYYTNAAR AARGGNGGNGTNACNYTNGAYGAYAAYCAYACNAARGCNGTNGARGARATGATGAARMGN ATHAARAGYGGNAAYATHGGNYTNMGNCCNGTNYTNCAYAARCARGCN---------CAR TCNYTNCCNGARCARGAYGARCCNAAYGCNATGAARGARYTNCARGGNYTNYTNACNAAR ATGMGNAARTCNMGNAGYGARGAYGAYYTNTCNGTNTTY---GGNGAYAGYGGNGTNGAY GARGARTCNGARYTNGGNAARATHYTNAARAARMGNATHCAR------------------ ---------GARAARGARACNTCNCCNCCNGCNATHAAYAAYGCN--------------- ------MGNCCNGTNCCNYTNCCNMGNAARYTNTCNACNATHCARGAYGARGCNGARGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATHCAYCCNTCNCARYTN TCNCCNGCNTCNYTNAAYMGNTCNCCNGTNYTNAARMGNGGNATHAGYCCNCARGARYTN GCNGTNCAYGCNCARGCNGTNATGCARAGYGCNYTNYTNAARACNCARYTNCARAAYCAR AGYGARMGNTTYATHAARAARCARCARGARMGNGCNAARTCNCCNAGYMGNCAR------ GTNGTNAARCCNCARCCNGCNGCNCARCCNGTNYTNCCNCCNACNCCNCARCCNAARGGN AAYACNGTNAAYACNTTYACNCCNACNTCNGTNYTNGTNAARATGCAYTCNGAYAARGCN ATHGARAARGARAARCARGCNCARGARGTNGGNGAYMGNAARCCNATGGARTAYATGCCN TCNATGGARGARYTNAGYGGNAAYCCNATGGTNCAYAAYATHGGNGAYATGAAYCAYGGN AARAAYATHTCNATHGAYGTNYTNAAYGAYATHAGYTTYYTNGAYCCNATHAAYCCNAGY YTNATHGCNYTNGARAAYCARATHGAYTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AGYAARATGAARMGN TCNGARMGNCAYATGATGMGNYTNAARAGYATHATHTGYAAYGTNYTNAARGARAARGGN GTNAARAARGGNGAYTCNATHTAYGARGCNTGYTCNAARAAYYTNYTNAAYGTNAGYATH ATHYTNYTNAARACNYTNCCNAAYTCNAARAAYYTNACNGAYGARATGAARTCNGTNGTN TAYGARCARGTNCARCARATHATHAAYYTNGARAARMGNMGNTCNGGNATHGCNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TCNGARAARTCNAGYTCNTCNTCN TCNMGNAARGAYAARAARMGNAARMGNAGYMGNAGYMGNGARMGN--------------- ---MGNMGNTCNMGNAGY---------------------MGNGAYMGNMGNTCNMGNAGY MGNAGYMGNGARMGNMGNMGN---MGNGARMGNGARAARGGNMGNMGNMGNAGYMGNAGY MGNAGYMGNGAYAARGAYMGNAARMGNMGNAGYAARTCNCCNGGNAARMGNTAYAGYAAR AGYCCNCARMGN---GARMGNYTNCCNGARYTNACNGTNGARGARMGNGAYGTNMGNACN ATHTTYTGYATGCARYTNTCNGCNMGNATHMGNCCNMGNGAYYTNGARGARTTYTTYTCN TCNGTNGGNAARGTNMGNGAYGTNMGNYTNATHACNGAYAAYAARACNMGNMGNTCNAAR GGNATHGCNTAYGTNGARTTYGCNGAYCCNGARTCNGTNACNYTNGCNATGGGNYTNACN GGNCARMGNYTNYTNGGNGTNCCNATHATGGTNCARCCNTCNCARGCNGARAARAAYMGN GCNCARCCNGCNGCNCCNGCNCARGCNCARAARCAR---GCNACNGARGGNCCNYTNMGN YTNTAYGTNGGNTCNYTNCAYTTYAAYATHACNGARGAYATGYTNMGNGGNATHTTYGAR CCNTTYGGNAARATHGTNGAYATHAARATHATGMGNGAYCAYGAYTCNCARMGNTCNYTN GGNTTYGGNTTYATHAGYTTYGCNAAYGCNGAYGAYGCNAARAARGCNYTNGAYCARYTN AAYGGNTTYGARYTNGCNGGNMGNCCNATGAARGTNGGNCAYGTNACNGARMGNACNGGN GARGGNGGNCCNGGNCCNCARAAY------GGNGTNGGNGGNCARYTNGAYACNGAYGAR ATGGAYMGNGCNGGNATHGAYYTNGGNGCNACNGGNMGNYTNCARYTNATGGCNAARYTN GCNGARGGNACNGGNTTYCARATHCCNCARTAYGCNGCNAGYGCNYTNAAYAAYATHAGY ACNCCNGCNACNATHCCNGGNATHCCNCCNGCNGTNCCN------CCNCCNACNACNCAR TTYGGNATGCCNCCNGTNGTNCCNACNCCNATHACNACNCARCCNCCNGCNCCN------ ------GTNACNAAYGCNCCNCCNATHGCNACNCARTGYTTYATGYTNTCNAAYATGTTY GAYCCNACNTCNGARCCNMGNYTNACNTGGGAYCARGARGTNMGNGAYGAYGTNATHGAY GARTGYAAYAARCAYGGNGGNGTNYTNCAYATHTAYGTNGAYAARAAYTCNCCNCARGGN AAYGTNTAYGTNAARTGYCCNAGYATHTCNGCNGCNGTNGCNTCNGTNAAYTCNYTNCAY GGNMGNTAYTTYGCNGGNMGNGTNATHATGGCNAARGCNGCNCARTTYGAYGAYCCNTTY TAYGGNCARAARCCNGAYATGGCNCCNTCNAARGCNCAYTTYAAYGTNAGYGARGARYTN MGNTCNTCNAGYYTNTCNYTNAAYAARAGYMGNATGGTNATGGAYGARGAYMGNTTYGAR GAYCARTTYYTNMGNTGYGGNATHTGYAARACNMGNTTYAGYATGTCNTCNYTNCCNMGN YTNYTNCCNTGYCAYCAYTCNTAYTGYCARCCNTGYGTNYTNMGNYTNTAYCARACNGCN AARGARCAYMGNCARAGYTTYCARTCNTCNYTNMGNACNGTNACNCCNCCNYTNACNACN GTNAGYGTNAAYTGYCCNACNTGYMGNACNAAYTTYGTNGCNACNGAYGARAAYATHYTN AARYTNCCNGCNGAYCAYMGNGTNGTNCARYTNATGGAYTTYGTNAARCAYACNGARMGN TAYACNATHTCNTTYTGYTCNAARCAYAAYYTNCARCCNYTNAAYTTYTTYTGYGARCCN TGYATHMGNCCNGTNTGYMGNGAYTGYACNGTNGTNGAYCAYAARGARAGYGAYGGNCAY YTNGTNATGGAYYTNGARGARGCNATGTCNAARTAYACNCCNYTNYTNGAYACNGCNATH GCNGARATGGAYTCNGARGTNYTNGGNATGGARGARAARATGGCNGCNYTNGARACNYTN ACNAARGGNGTNGAYAARGTNAARAGYGARYTNATHGCNGARAAYMGNGCNTGYATGGCN MGNYTNMGNAAYYTNATHACNGARMGNGARAARACNYTNGARGCNAARATHCAYYTNGAR ATHGARAARGARAARACNAARYTNMGNGARAARAARGARTCNYTNGTNTCNCARAARGAR AARGTNGARACNCARACNGGNMGNYTNAARAARGCNAARGARGARAGYAAYGTNGARGAY ATHTTYCAYATHCAYCARGARGTNAARGARTAYATGAARAAY---TCNGTNAARATHMGN GAYGTNAAYGARGGNAGYYTNGCNTCNATHTCNYTNAAYACNMGNGAYGARTCNYTNYTN GCNTCNMGNATHAAYAGYTTYGGNGAYGTNATHACNAARGAYGAYACNACNGTNTCNMGN CCNAARTCNATHYTNMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TAYGCNTCNTTYTGYTTYTGYTTYCCNGAYTCNTAYMGNCARTTYGGNGAR AARTTYAARGAYGARYTNGTNTAYYTNGTNTAYGGNTGGATGGCNGGNATHMGNCCNGCN CCNMGNAGYTGGATGGCNTGGGAYATGTGYCAYYTNGARCCNCCNAAYYTNAARATGMGN GARGAYATGATGCARAARAARAAYAGYAARAARATGACNTCNTTYATHGAYTTYGAYTAY YTNGAYTCNYTNATHTCNGCNAAYGCNAGYCARTAYGCNTCNACNATGTCNYTNGCNCAR TCNACNTCNAARTCNTCNACNATHTCNAAYATGGGN---GCN---MGNAARACNMGNAAY CAYGCNMGNATGAGY------------AARCCNYTNTTYMGNACNTCNTCNCCNAAYAAR ACNCARTCNCCNACNTCNTCNCARGAYTCNAAYYTNATHGAYGCNGTNGCNGAYGCNCAR AAYAGYCCNMGNAAYMGNGGNAARGAYGGNAAR---AARGGNGGNGARTCNYTNACNCCN GCNMGNGAYATGAARMGNCARAGYGAYGCNYTNACNCCNATHMGNGARATGACNAGYGAR GAYGARGAYGARGAYATHGGNAARAARTTYTCNCARGTNTCNATGAGYCARATHMGNGAR AAYMGNGCNAARGAYGARTAYGTNATGGARTCNCAYCCNGTNGGNMGNGGNTAYGARTTY GTNMGNACNGCNTTYAAYGTNGARGGNMGNAGYCCNYTNGTNGCNCAYTTYYTNAAYATG AARGGNYTNACNCARGAYGTNGGNCARAAYGTNTGGATHCARMGNGTNGARGTNGAYGAY YTNCCNTCNYTNGAYGCNACNACNTAYAARAAYGTNATHAGYGARTCNTCNAARACNATH AARAARYTNGARACNGGNTTYCARGAYATGTAYCARAARAAYTAYAARGAYAGYCARAAR TTYATGAARCARCARCARAARATGYTNMGNGARCAYATGMGNAARCARTCNGCNYTNYTN GCNAAYGARAARGARGTNAARGTNYTNTGYGAYYTNATHATHYTNGARCARMGNAARAGY CARGAYTCNGTNTCNGCNGGNGCNAGYGCNGCNATHGARGCNGCNYTNATGGCNCARGAR ATHCCNGARGARGARAARYTNYTNCCNCCNGAYTTYATHTCNGAYGARGARAARMGNGTN CAYACNGAYTTYTTYGAYGGNMGNCCNCCNAARACNCCNGARMGNTAYYTNAARATHMGN AGYTAYATHGTNGAYTGYTGGATGAARAGYAARCCNGCNTAYYTNAAYAARACNTCNGTN MGNCCNGGNYTNAARAAYTGY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CCNATGTCNYTNACNGTN CCNGARTCNTGGGCNAARCCNATHAAYCAYYTNTGGCARTTYTCNCCNMGNACNGARGAY GCNGTNAGYAARTTYAAYGARACNATGTCNCAYMGNAGYCCNCAYTGYTCNGTNTGYTCN YTNTTYCARMGNYTNGAYCCNGAYGCNGARTGGCCNGAYYTNCARGCNGGN------YTN GGNGAYMGNGCNGTNATHCCNTCNMGNTCNYTNCCNATGATHCCNGARGCNTCNTTYGCN GTNAGYGCNTCNAAYMGNACNCCNTTYTGYGARTAYTCNCCNYTNGAYCARGAYGGNYTN AGYGCNYTNYTNGTNTGYTCNTCNTGYAGYGTNTGYGTNCAYGCNAGYTGYTAYGGNGAR ATGMGNAARACNGAYAAYGAYTCNTGGAARTGYGTNGCNTGYGTNTCNYTNGARCARTCN GGNAGYCCNACNTGYGARYTNTGYTAYYTNMGNGGNGGNGCNYTNAARCARACNYTNGAY GGNCAYTGGGCNCAYATHGCNTGYGCNYTNGTNATHAGYGAYGCNTCNTTYAARAAYGTN MGNGGNMGNTCNCCNATHGTNACNTCNMGNATHGAYCCNGARMGNTTYAARYTNAARTGY TCNYTNTGY---------------GGNGTNGCNTCNCARTAYGCNTGYATHCARTGYTCN CAYGGNMGNTGYACNACNGCNTTYCAYGTNTCNTGYGCNTTYATGGCNGGNATHAARTTY GARATGAGYGAYTGGCCNGTNCCNATHTAYGTNTCNTGYMGNAARCAYYTNGCNACNAAR AGYAARGTNGARMGNTCNMGNGARATGCARGAYYTNGAYGTNCAYTGYYTNGCNYTNGCN AARCAYAARAAYAARMGNTTYTAYTGGGCNAARGTNYTNCAYGTNGARMGNATGAARYTN TAYGARGTNGAYTTYGAYGAYGGNTCNTTYAGYGARGAYYTNYTNCCNGARGAYATHGAR AGYMGNGAYTGYYTNMGNGAYGGNCCNCCNAAYAARGGNGARCAYGTNYTNATHAARTGG GARGAYGGNAGYTCNTAYGGNGCNACNTTYMGNMGNGTNAAYAAYAARGAYGTNTAYACN GTNGARTTYGARGAYGGNTCNYTNTGYCAYGCNMGNMGNGARGARYTNTGGAGYGARACN GARGARATHCCNACNCAYATHMGNAAYMGNATGTCNCARGCNACNGARCARMGNTTYGAY ATGTAYGAY---AARGARTCNCAYGAYGGNMGNMGNAAYAARAARAARGTNAAYTAYYTN MGNATGYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTCNGTNCCNGARATHCARMGNYTN YTNGAYTGYCAYMGNTCNYTNTCNTTYGAYGARAAYACNCARAARGTNAARTGYAGYYTN ACNAAYCAYGARATGCCNGCNAAYGTNAGYGCNATHGARAGYTAYGTNAGYGGNAARAAR TAYAARMGNYTNGCNGAYYTNGARGCNYTNGAYTAYGARGAYCAYAARATGCAYATHGTN CCNAGYAGYAARAARGAR------AAYGARYTNTTYTGYMGNYTNACNYTNMGNCAYYTN GARAARACNGCNAARGCNATHCARMGNCAYATHAAYGGNMGNAARTAYAARAAYTCNYTN TCNMGNTGGAAYGARTGYCARAARACNGGNACNAARTTYATHGCNCAYATHMGNMGNAAR GCNAARGGNCCNGAYGARTCNGAYAAYGAYAGYGTNGTNAGYAAYGAYGAYGCNGAYGAY GARGAYAAYGCNGARGGNGAYGAY---GAYGAYATGAGYGAYYTNTAYCCNGARGCNGAY TTYCARGARGARAAYGGNTCNGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CCNATGCCNCCNGGNTCNATGGGNTGGCCNATHATHGGNGARACNATHCAR TTYYTNMGNAARGGNTCNGAYTAYTAYGCNGARAARTTYAARGARTAYGGNAAYATHTTY AARGTNAAYGTNYTNGGNACNAARATGATHMGNGTNACNGGNTCNGARAAYATHAARACN YTNGTNAAYMGNGARACNAARCARYTNAGYATGAARTGGCCNACNGCNGTNAAYGTNYTN ATGGGNGCNAARAGYYTNCCNACNGTNGTNGGNCCNGARCAYCCNACNYTNAARAARAAY YTNCARMGNGCNTTYACNTCNATHMGNYTNGCNGAYTAYTTYCCNTGYGTNCARAARAAY ATHMGNGCNCAYTTYCARAARTGGGCNAAYGARGAR------------CARATGYTNGCN TAYCCNGCNTGYGARAGYYTNATHGCNGAYATHATGYTNGARYTNGTNYTNGGNTGYAGY AARGARGAYGAYGTNGAYGGNAGYGTNMGNGCNGCNTTYMGNGAYATHAAYCAYAAYYTN TTYTCNATHCCNATHAARTTYCCNGGNGGNGGNTTYAGYMGNGCNTGYGARGCNMGNAAR GTNATHYTNGAYTTYGTNCARTCNMGNATGAAYGGNGARAAY---GARAARGAYMGNGTN AGYATGATGGAYATHYTNACNTCNYTNCAY---GGNCARAAYGARAAYATGGAYGARGGN AARGTNAARGAYAAYGCNYTNGGNYTNYTNATHGCNGGNGCNGCNAGYACNTCNGGNGCN ATGACNTGYYTNYTNYTNYTNYTNGGNACNCAYCCNGARGTNYTNGARAARGTNMGNGAR GARYTNMGNGCNGCNGAYYTNTTYGGNAARGAYGCNGTNGTNGAYGTNAGYTAYGAYYTN YTNCARAARYTNGARTAYGTNCAYTGYGTNGARAARGARGCNYTNMGNTAYYTNCCNCCN GTNAGYGGNTGYTTYMGNAARGCNGARAAYGAYATGGANYTNGAYAANTAYNNNATHCCN AARGAYTGGACNGTNNNNTAYAGYATHMGNGAYACNCARGCNYTNGARNNNAARYTNATH NNNGAYGGNGAYNNNTTYMGNCCNTCNMGNTGGCARCAYAANGARCARNNNNNNGAYNNN NNNGAYATGTAYTCNTGYMGNTAYATGCCNTTYGGNTTYGGNCCNMGNATGTGYYTNGGN MGNCARYTNGCNMGNATGATHATGCAYACNTTYATHGTNGARYTNGCNYTNTCNGCNMGN TGGGARGTNATHAAYCCNGAYTGYCCNYTNGTNTTYYTNCCNATHGCNAARCCNAGYGAY GAYATGCCNATHMGNTTYCAYGTNYTNTCNGCNTTYMGNAAYYTNCAYMGNGCNMGNAAR GARGTNTTYGCNGGNGAYGARMGNGCNYTNAAYGARYTNMGNCAYMGNATHAAYTCNGAR TTYMGNGARAARYTNGARGARACNGAYACNGCNAARATHGAYGAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGMGNGAYAGY CAYMGNYTNTTYYTNCARGCNTTYATGTCNAARGGNGTNATGAAYACNAGYGARGTNAAR GCNACNTAYYTNCARAGYATGAAYMGNTTYGGNGARACNTTYGAYGCNGAR--------- ------AAYATHACNGGNCARATHCCNCARTTYGTNMGNACNATHAAYYTNGCNATHGCN CCNTTYAAYYTNGARATHMGNAARGGNATHCARGARCAYGAYGGNAGYAGYGTNTAYTGY YTNGTNAAYTCNGTNGARAGYGTNATHTCNMGNYTNTCNTCNACNTAYACNCCNTGYGAR YTNGARYTNTTYAARAARATHATHGARCARATHGTNGARTCNGAYGARGGNAARATHGGN TCNMGNGTNGCNYTNAAYYTNACNGARAARYTNGARAARMGNATGGGNAARGARGARGCN CARAAYTTYYTNAAYAGYYTNGARCARGARAARTGGATHACNAARGGNGGNGAYGGNAAR ATHGCNYTNTCNGTNMGNACNATHYTNGARYTNGAYCARTAYYTNCARGAYATGTAYCCN GCNYTNATHAARAARTGYAAYATHTGYAAYATGATHTCNYTNCARGGNGARYTNTGYAAY AAYTGYGGNATHAARATHCAYTTYMGNTGYYTNGARAARYTNTTYTCNAARCARACN--- GARMGNAARTGYCCNGTNCCNAGYTGYMGNGCNCCNTGGGGNCARTGY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNGTNAAYAAYCARATHYTNGAYTGGTCNTTYAARYTNGAYGGNATHTTYAGY AAYGCNGAYCARGARGTNGTNTAYAGYACNGTNGCNTCNGAYATHGTNTCNGGNTCNYTN GAYGGNTAYAAYGGNACNYTNATGTGYTAYGGNCARACNGGNGCNGGNAARACNTTYACN ATGACNGGNGCNACNGARAGYTAYMGNCAYMGNGGNYTNATHCCNMGNGCNATHTCNCAR YTNTTYMGNCARATHGARGAYMGNYTNGARTAYAGYATHACNGTNMGNGTNTCNTAYATG GARATHTAYAAYGARCARATG--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AGYGAYGTNCARCARATHGARTCNATHTTYGARTGGGAYATHCARMGN TAYTCNGARAARYTNGARATGGARAARAAYGGNACNCARGARTGYGCNGTNTCNGAYTTY TTYCARATHGGNTAYCCNGGNTAYAARGCNMGNYTNGARATHTAYYTNAAYGGNAAYGGN TCNGGNCAYAAYAARTGYATGTCNTTYTTYATGMGNGTNAGYAARGGNMGNTAYGAYGAY TTYYTNCARTGGCCNGCNAARTTYACNYTNAARTTYATHYTNATHAAYCARGAYGAYAAR AARGCNGAYTCNYTNATHTTYGGNMGNGAYGAYAAR---GTNTTYAARTAYGAYMGNCCN MGNGGNGAYTCNGAYGAYGARAGYGAYTCNTGGGGNYTNGTNGARTTYGTNTCNCAYAAR ATGATGGTNACNMGNAARTAYATHAARGAYGAYGCNATH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AAYYTNGARYTNATHCARGAYGTNCARTAYTCN---GCNACNACNAARAARYTNYTN GTNMGNYTNAARGAYCARGTNCARMGNMGNGAYYTNGARGAYYTNCAYCCNGTNGCNGGN GARYTNATGGARGCNGARCCNACNGGNYTNGTNTCNGGNGTNGGNATHACNYTNAARGGN TGYMGNGAYAAYGGNTGYYTNGAYGAYCARGGNAAYGTNTAYGAYTTYGTNTCNMGNTAY TTYCCNCCNTGGYTNGGNATHTCNGARGAYCCNGTNACNGGNTCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGGGNAAYAAYCCNAARAARCARTCNAAR TCNTTYAARGTNYTNCARTGGATGACNGARACNGARAARGAY---------GAYGARGAY TCNGARGCNGAYTCN---------AARTCNMGNCCNMGNMGNTCNAARGAYCCNGAYYTN MGNCAYAAYGCNGAYGAYGAYGARATGMGNTTYACNGGNYTNCAYTCNAARGCNGAYATH CCNTCNMGNACNTTYGAYMGNYTNAARAAR------------------TCNACNCCNAAY GARAAYGGNCARGAYTCNCCNCARGCNGARGAYGARACNGAYGARGTNGGNAAYTAYAAY GARGCNTCNATHMGNTAYACNGGNAARAAYATHCCNTCNCCNGCNTTYMGNGTNYTNCAR ACNTGGGCNGARCAYGAYCCNGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GTN GGNATGGTNGCNGTNTTYYTNGAYCCNATGACNGAYYTNCARAGYGTNATHYTNATHMGN CARTAYMGNCCNCCNATGGARACNTAYACNATHGARTTYCCNGCNGGNYTNATHGAYGCN GCNGARACNGCNAGYCARGCNGCNATGMGNGARATGAARGARGARACNGGNTAYGAYGTN ACNGTNATGGAYGTNTCNCCNGCNACNTCNYTNGAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MGNGCNAGYAGY MGNTAYTTYTAYCARAAYMGNYTNACNGAYCAYACNCARTGGGARTAYCCNGARGTNCAR GARGAYAARGGNGTNGTNMGNAARAARMGNMGNAGYAARGARGARGARMGNGARGARGGN AARACNMGNGGNAGYAGY---------------TCNAGYMGNACNAGYMGNCAYMGNAGY AARAARACNCARGAYAARGARMGN------------------AGYAARMGNGAYMGNCAY AGY---AGYAGYCAYCAYCAYMGNAARAARAARMGNMGNMGNMGNGAYCAYAGYAGYAGY AGYAGYAGYAGYGARGARGARGARAGYAGYCARTCNMGNCAYMGNCAYMGNAGYAARMGN AARAARMGNTCNAARTCNGAYAARTCNCCNAGYYTNGARYTNATHGGNGARTCNGAYGTN ATHGARGAYAGYCCNCCNTCNTCNTCNAAYYTNGCNGGN---CCNGARGCNTCNACNYTN GARATHACNAAYACNGARGGNAAYGARGARAARAAYGTNTTYACNAGYGGNAARGAYCCN CCNACNCCNCCNTCNGTNGAYAARGARGARGARGARAAYAARGCNGAR---------GAR GARAAYGTNGARGARCARGCNAAYCCNGARGGNACNGCNGAYGTNGCNGARTCNATHGAY GGNGARGARATGGCNGARGGNGARGGNGARATGGARGARGAR---------GARGARGTN ---AAYACNGCNGTNATHATHMGNGCNCCNCARATHATHGTNCCNTCNTAYGTNGCNGCN ATGAAYCARCCNCARATGTAYGCNGCNCCNCCNATG---TCNTCNTCNGCNACNGTNTCN GCNCCNGCNGCNGTNGCNGARAARGARGCNGAYACNACNCAYTCNYTNGARGAYACNGAY AARGGNAGYAARAARAARAARAARGAYAARGCNGGNAARGARAARTCNYTNTCNGCNAAY TCNAGYATHATGATGAARAARAARMGNGTNTCNTCNATGGTNCARAARTGGCARCARGTN AARAARGARGTNGARAARGARGAYMGNGCNAARGARYTNMGNCARGCNGCNATHMGNGAR AARATHAAYCARYTNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CAYAAYAARGCNTCNYTNGGNYTNCCNATGCCNMGNAARAAYTAYTGY CARTGGTGGGAYTCNGARGTNTGGGARACNYTNCCNYTNCCNMGNGAYGARGTNAAYAAR GCNAARGTNGTNCAYACNGCNGTNYTNACNGCNCCNCARMGNGAYGARCAYGTNAAYTCN TTYTAYGARCAYTAYMGNCCNGARGARYTNTCNGTNTTYGAYGARATGTAYCARATGTAY YTNTCNCARGCNTGYTGGAARCAYYTNCCNAARCAYTCNAGYGAYTTYAGYCCNTTYTGY GTNMGNCAYGTNGCNGARACNGTNGARTCNAAYCCNAGYATHTCNGGNAARGAYTCNACN TCNTCNACNACNTCNTTYGGNTCNGARGGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CARCCNTCNTCNATGTGGGAY GCNAAYGCNATGAAYGARGCNACNCARACNGCNCAYAARATHCARATGGARAARATGAAR AARGARMGNGARGARGARAARYTNAARGARGARGARMGNATGCARCARGAR--------- ---YTNCARAAYGARATHMGNAARCARCARACNGARYTNGARMGNCARMGNGARCARGTN MGNMGNGARAARGARGARYTNGARMGNGARMGN---ATHAARYTNGARGARGTNMGNMGN GARGARGARMGNYTNGCNCARYTNGARATGGAYMGN---------CARAARAARGARMGN YTN---------------------------------GARCARGARMGNAAR--------- ---------MGNCARGARGAYGARAARAARMGNGARMGNGARYTNAARAARCARGARGAR AARMGNMGNAAR---------------GARGARGARAARCARYTNTTYGARGARCARAAR MGNCARGARGARGCNMGNMGNATHCARGARGARATGMGNCARMGNCARGARATGCARMGN CARCARGARGARYTNCARMGNCARATGGARYTNCARCAR------------ATHCARGAR GARGARGARMGNATGAARMGNGARGCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MGNGCNAAY TAYTTYTAYTGYGTNMGNGTNACNGAYYTNGAYGTNTAYAARAAYATHGARAAYGCNYTN GARTGGATHGTNGAYAARGARCCNAARTTYGGNGAYTTYTGYTAYACNAARGARATGYTN CAYGTNACNYTNTGYGARGTNTCNYTNCARAAYGARGAYGARATHGCNYTNGCNTCNAAR GTNYTNCAYGAYCAYCARGCNGAYYTNMGNAARATHACNCCNACNACNCCNYTNTGYTTY MGNGGNATHTCNGAYTTYCAYCARAARGTNATGATHGCNAARGTNGARCAYGGNGAYGAY TTYGTNACNTTYGCNGAYAARYTNACNTCNYTNGCNAARGAYGCNGGNGTNAAYGTNGTN CARAAYCAYGAYTTYAAYCCNCAYATGACNATHYTNAARGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATHYTNAARAARCAYAAYAAY AAYGTNATHGARTAYGCNTCNGAYYTNAGYMGNCCNGGNTCNTCNATHGGNMGNTCNTCN MGNTCNTCNGAYGGNMGNGARACNCCNATGATGGCNGCNTCNCCNGAYMGNATHTCNMGN GCNTTYGARGTNACNGAYCARGTNGARGCNGTNAAYAARCARYTNAAYGTNAAYAARTTY GAYGARGTNTGYGCNCAYYTNMGNTCNACNYTNGARAARGARGTNGAYTGYYTNYTNGCN GAYATHGARTTYYTNCARAARTGYYTNGAYAAYGARGCNAAYATHMGNGAYTCNATHGAY ACNCCNCARATHTCNMGNGARCCNACNYTNAGY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GCNTCNGARYTNTGY AAYAARGCNAAYGARGARTAYGTNGARGARAAYTAYCARAARGCNATHGAYYTNTAYACN GARGCNYTNGCNYTNGAYGARGGNMGNGAYGAYATHTAYTGYCAYMGNGCNCARGCNTAY YTNTCNYTNGGNAAYACNACNGCNGCNATHAARGAYTAYGAYGARGCNATHAARYTNAAY AARAGYAAYCARAARGCNTAYATHAARAARGGNTCNATHYTNYTNAARATHGAYGAYGTN YTNCARGCNCARAAYGTNTTYAARGARGGNCARCARCAYTGY---GGNGAYAARGAYTTY GARGAYTGGYTNAGYAARGTNGARAAYMGNATG---------------------AARGAR YTNGGNATHTGYCARCCNACNCARGCN------------------CCNACNYTNAARTAY AAYTGGTAYCARACNCAYACNCAYGTNGTNGTNACNGTNYTNGTNAARAGYGTNAARAAR GARGARYTNACNYTNAAYGTNGARGARMGNTCNYTNGGNYTNACNATHMGNAARGGNAAY CAYACNAGY---GAYYTNAAYGTNATHYTNGCNCAYCCNATHATHGTNGARCARACNCAR TCNAARYTNYTNTCNACNAARATHGARATHAARYTNAARAARCARGARGGNATHCARTGG GCNAARYTNGARGGNGAYCCNGAYGARATHGARACNACNGTNYTNCCNCCNTGYGCNGCN CCN---CARAAYGCNGARGCNCCNMGNTAYCCNAGYTCNTCNCAYTAYACNMGNGAYTGG GAYAARYTNGCNGCNGARGTNACNGARGARGARAARAAYGARAARYTNGARGGNGAYGCN GCNYTNAAYCARTTYTTYCARAARATHTAYGCNGAYGCNTCNGAYGAYACNAARAARGCN ATGATGAARTCNTTYTCNGARTCNGGNGGNACNGTNYTNAGYACNAAYTGGAAYGARGTN GGNTCNAARAARGTNGAYGTNAARCCNCCNGAYGGNATGGARTAYAARAARTGGGARTCN ATHAARATGCCNAARMGNAARTCNGARGCNAAYACNGCNGCNGAYTCNCCNAARAARGCN AARGCNGARCCNAARGCNGCNGARTCNCCNAARAARGCNAARGCNGARCCNGCNAARGGN TCNGGNAARMGNGGNMGNGGNMGNCCNTCNYTNACNGAYGARGARMGNGCNAARMGNGCN GCNGCNAAR------GTNTCNGGNMGNGGNMGNGGNMGNCCNAARGGNTCNACNTCNAAR TCNAARAARAGYAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ACNGTN TGYCAYTCNTCNCCNYTNATHAAYATHAGYACNTCNATGGTNGAYCCNAAYYTNATHATH ACNGGNACNTGGGGNGCNTCNCARAAYTGYGCNYTNTGGGGNTAYAARMGNAGYAGYGAY ACNTGYGTNYTNAARTAYMGNTTYGAYGARCAYCAYGCNACNATGGCNAAYYTNAGYCAY GAYMGNTTYATHGGNACNAARGAYACNGTNGCNACNATHTAYGAYACNGCNACNGGNAAY AARGTNCARACNYTNTAYGAYGARAGYAARGCNAAYAAYTAYAARTTYAAYGARGCNTCN TTYAAYCCNACNGAYGAYYTNGTNYTNAAYGAYGGNAAYYTNTGGGAYGTNMGNTCNAAY AARYTNATHTAYAARTTYGAYAARTTYAAYCARTAYACNAGYGGNTGYTTYCAYCCNMGN GGNYTNGARGTNGTNATHAAYTCNGARATHTGGGAYATHMGNTCNTTYMGNYTNYTNCAY ACNGTNCCNGCNYTNGAYCARTGYCARATHATGTTYAAYCAYGGNGGNGAYGTNATHTAY GCNATHAARGTNGAYGAYGARCCNTCNGGNGAYATHTTYATGMGNMGNGAYTAYGCNTCN ACNYTNMGNACNTTYGAYGCNYTNCAYTAYACNGGNATHGGNACNTTYGAYYTNAARACN AAYAGYATHTTYGAYYTNGCNATHGAYMGNAAYGAYCARYTNGTNGGNATHATHGARAAY TCNTCNCAY---GARACNGARGCNGARGARTCNYTNTGYMGNGTNTAYGARYTNGGNAAR GTNMGNGTNCCNGARGAYAARGCNGARGARGARGARGAY---CCNCARAAYGAYAARGGN GAYTAYGAYGAYGAYGAYGAYGAYGAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNCCNGGNGTNYTNGAYGARYTNATH AGYTAYTTYYTNGAYGGNACNATHCCNAAYTGYCAYGGNATGGAYTTYGARGAYGTNTGY YTNGAYGARGAYGTNGAR---------GARATGGAYGARTTYGARAAYGTNGTNYTNCCN AAYATGMGNGARGAYTAYAAYACNAARAAYTGYTCNTGYCARTGYCAY---AGYAARCCN GARGAYGTNCARTTYCAYMGNMGNATHAARCAYTGYATHTCNTGYAGYYTNAARGTNTAY GAYGGNCARCCNGTNYTNAARGTNTCNMGNAAYGARTAYAARCCNATHTCNATHATHTAY CCNTCNGARGARCARGARGARAARGARAARYTNGCNAARGCNGARAAYGARGCNACNCAR GTNGCNYTNGCNAARGCNAARGTNCAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARAAYACNCARGGNCARGAYGGNGGNAAYGAYGAYGAYGARTAY GTNCCNCCNAARCCNGARGTNAARGARATHAARGARGARGGNTCNYTNTTYTCNAARMGN TGYAARYTNTTYTAYCARAARGARGGNCARTGGATHGAYAARGGNGTNGGNAAYGTNCAY GTNAARCCNATHGARGARTCNAAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AARGARCAYAARATHYTNAARCAYYTNGARCARTCN GAYAAYTCNAAYMGNGTNCCNGCNCAYMGNGTNMGNGARGAYGGNGTNCAYAAYTTYGAR AARGCNAAYAAYMGNGARGARATGAAYGCNATHATGMGNGGNTCNCCNGCNTCNAGYGAY GTNMGNCCNMGNAGYGGNAARAARATHATGCCNCAYYTNCARAARTCNGARYTNTGG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNACNCAYYTNCARGGNAAYGCN GGNYTNATGATHACNGGNCAYAGYYTNGGNGCNGGNGTNGCNTCNATHYTNTCNGTNYTN ATGMGNCCNCARTAYCCNGAYYTNATGTGYTTYGCNTTYTCNCCNCCNGGNGGNYTNATG ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNATGGGNAAYCCNAARATHTAYGARMGNATHYTNATGTAYGARGCNYTNGARYTN GAYGTNYTNAARAARCARATHTCNGAYGCNGGNATHMGNATHGGNATGGCNMGNYTNCAR GAYTTYYTNGAYGARMGNTGYATHACNTTYTCNATGAARAAYATGAGYAAYMGNAAYAAY MGNCAYCCNMGNAARGCNGGNAAYAARMGNAAYCCNYTNAARMGNAARCARGTNTCNCAY TCNGCNATHGTNGAYACNMGNATGGTNTCNATGGCNGARAARYTNGAYGGNTGGYTNGGN AARYTNAARGARAAYATHYTNGARGARYTNYTNACNTCNYTNATGGCNTCNYTNGAYTCN CARCARGAYGARCAYAARAARGCNACNYTNGARYTNCAYACNGARAARGCNTCNYTNCAR AARGARGTNAAYMGNYTNAAYGARCARATHAAYAGYYTNGARTGYAGYYTNCARCARAAR TCNACNGTNGTNAARAAYYTNACNGAYTCNYTNGCNGCNCARAARAARAARGTNGARATG GCNAARAAYTTYTAYTCNTGGAARGCNGGNCAYTCNGAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TGYTAYAARTGYGGNGGNMGNGGNCAYTTYGCNMGNGAYTGYMGNAAYAGYTCN GGNGGNGGNGCNGGNTTY------------------------------------------ ---ACNCCNCARAARTGYTAYAARTGYAGYMGNGTNGGNCAYTTYGCNMGNGARTGYCCN CARGAYCARGARMGNTGYTAYAARTGYAAYGGNYTNGGNCAYATHGCNAARGAYTGYGAR AARCCNATH---ACNACNGGNGCNTGYTAYAAYTGYGGNAGYAGYGAYCAYYTNCARMGN GAYTGYCCNCARGCNATHGTNAARTCNTGYTAYMGNTGYGGNGARTCNGGNCAYYTNGCN AARGAYTGYGGNGGNCCNATHGCN------------AAYAARTCNTTYATHGAYGAYMGN AARTGYTAYACNTGYGGNGGNATHGGNCAYYTNGCNAARGARTGYCCNACNCCN------ ------MGNAARGARTGYTAYMGNNNNNNNNNNNNNGGNCAYYTNCARAARGAYTGYCCN GGNTCN---CARAAYGAYACNCARTGYTAYAAYTGYAAYGGNATGGGNCAYATGGCNMGN GAYTGYCCNGCNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATGACNGCNACNMGNYTNCARTCNAGYATHYTNGARGGNTTYCARAAYGCNGAR AARTGYCCNCARGTNAARGCNAARTCNATHGTNACNTGYGARYTNATGACNCAYCCNGGN TAYGCNACNGGNGTNCAYGAYGGNGGNTTYAAYGGNTCNTCNGAYGARTTYGGNTGYTCN CARGAYMGNGARCAYGARATHGGNGTNYTNAGYTCNCARCARATGTTYCARTTYTAYMGN GARAAYAAYATH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNCCNGARCCNGARCCNGAR CCNGARCCNGARATHCCNACNGGNCCNCCNCCNCCNAARCCNGGNGAYGARGARTGGGAY TTYGTNGAYYTNGAYATHGAYAAYGARYTNGCNAARGTNYTNGTNYTNCAYTGGGARGAR ACNGARAARACNTAYGTNAAYAGYTGYAARCAYATHTTYMGNAAYGTNMGNCARGARMGN GARGAYATHTAYMGNTAYTAYTTYCARATHMGNAARGAYTTYYTNCAYTAYYTNMGNMGN CCNGAYTGYAARCARGAYTAYGTNTCNCARTGGCARAARACNTAYAAYGARGTNTCNGAY GAYATGMGNGAYGAYGARGARACNAARGCNGARYTNCAYCARCARGTNGAYGAYYTNMGN GARMGNYTNTGGAAYATHTGYGAYGAYMGNAARGARCARGCNGARAARGARMGNGARACN ATHATHAAYGAYGGNTGGYTNGARGAYMGNYTNGGNGTNYTNAGYAAYCAYTAYYTNACN GTNATGCARTCNGARGTNGAYMGNYTNCARGAYACNGTNMGNATGYTNAARGAYTAYTAY MGNGGNATGGAYGGNCAYGTNCCNGAYGARYTNAAYCCNGAYTAYGARMGNATHCCNYTN ATHGARYTNCCNGTNGARMGNCCNGARACNCCNGARGGNGCNMGNAGYGARACNGCNCAR TCNCCNATHGAYGAYGCNAARTCNGAYMGNTCNGCNTCNGCNMGNTCNAARTCNCCNMGN GGNGGNMGNMGNTCNAARTCNCCNAARGAYMGNGCNAARTCNCCNAARGGNTCNMGNTCN TCNMGNACNGCNTCNGGNAARAARAARGGNAARGGNGGNAARGARACNCCNCARCCNGAR GCNCCNAARTCNTCNGARGGNATHGGNMGNMGNATHATHATHCCNYTNGTNCCNMGNMGN CCNGCNTCNCCNGAYGCNGAYGCNAARACNGGNGCNACNCCNAGYAARGAYAARAARGAY AARAARGGNGTNAARAARGGNCCNTCNGCNACNGAYGARGTNGTNGGNACNGARAGYCCN GTNCCNCCNCARGAYYTNGAYGARAARYTNATHTTYGAYGGNTAYACNTTYGCNGTNAAY GGNYTNACNCARYTNATHCARTCNGARATGCARGCNAARGARGCNGARGARGARGCNGAR MGNYTNAARGARCARGARAARGARAARGARAARGARAARGCNAARGGNCCNAARGCNGCN AARGGNGGNAARAARGCNAARAGYMGNAGYCCNTCNCCNAARAARGGNGGNAARGGNAAR GAYTCNGARACNTCNGCNACNCCNCCNCCNGCNCCNTCNGARATHAGYGARGARGAYCAR CARAARAARTCNTCNAARGARMGNGCNMGNGARGARTAYTAYTTYTCNATHCARGARGAR GARCARGCNGCNAARGTNMGNYTNGARYTNGTNMGNYTNYTNGCNTGYGCNGTNYTNCAR GAYYTNAARGCNAARGCNGARGARGCNTTYAARGAYATGAAYGAYTGGYTNGGNGCNMGN TAYYTNAARGARATGGARAGYATHGAYCARATGTCNGARGTNATGMGNAAYGGNATHGAR ATGAARGARAARYTNACNAARGARATHYTNYTNGARCARGAYAAYTTYGTNGTNGAYGAR GAYYTNAARGTNYTNMGNACNCCNAGYCCNCCNCCNYTNCCNCCNCCNATGGARCARCCN ACNGCNGARCAYTTYACNGTNGCNCARYTNTCNTCNYTNTAYGARCARTTYMGNTCNTCN GCNCCNACNGGNATHATHTCNAGYAARGCNTTYGTNGARATGTTYGARAAYYTNGTNTCN GTNACNCAYGGNATGGARGCNYTNCCNGAYGTNTGGACNCAYATGTCNYTNTCNCARATH CARGAYYTNGCNGCNATGYTNTCNTCNGARAGYGAYTAYGTNGAYTGGMGNMGNYTNYTN GTNGCNYTNAGYCAYCCNATHCCNACNCCNACNCARCARCARYTNYTNGAYACNYTNGTN MGNTTYAARGARATGGAYCARAARAAYACNGGNAAYGTNACNMGNGARCARTGGCARMGN ATHCCNYTNTGGTTYACNATGGARTCNATGCARGARAAYGCNTAYGAYMGNYTNGCNAAY YTNGAYMGNGCNYTNTTYGARATGTTYGCNGAYCAYTCNGGNCCNATHTCNCAYYTNCAY TAYGARACNTTYYTNATGTAYTTYTCNGCNACNGCNAAYTAYCAYGARGGNTTYYTNMGN GCNYTNAGYATHGCNACNTCNCARCAYATGCCNMGNYTNGGNAARCCNTCNYTNGTNTCN CARGCNACNCARYTNGGNGARMGNGCNTCNAGYATHGTNGAYAGYTTYATHCARGARGGN ACNGARTAYAARGAYGARGAYAARCCNCCNTCNGARCCNCCNATGTCNGAYGARAAYGTN CCNCCNGARGCNAAYGAYGCNGTNGTNTCNGTNGAYGCNYTNTTYMGNGTNYTNCAYCAY GGNGARATHTCNAARGGNGAYAGYCAYMGNTTYAGYGTNACNGCNGAYCCNGARGARCAR ACNTCNTAYGARMGNYTNTGYGCNGTNTTYCARGARYTNAAYGARGAYGAYAGYACNTCN CCNATHYTNTAYAARATHYTNATHGAYCAYCCNYTNGTNCARGAYGTNGTNGTNGCNTGY AARCAYTTYAARGGNYTNGAYATHAARACNYTNYTNAGYGGNTCNTCNCAYGAYGTNGCN GARATHACNAGYYTNAARACNATGGAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GTNTGYGGN MGNYTNMGNCCNYTNGCNATHGGNTTYTTYMGNAARACNGCNAARGCNTCNYTNCAYACN ACNTCNMGNAARTCNGGNGARGCNYTNTAYMGNGARAARATH------TTYGARTAYAAR GARCCNMGNTGGATHCAYCAYGCNGGNACNGCNTTYAGYGCNTTYYTNTGGTAYTGGATH YTNTAYCAYTGYTAYTTYGARTTYGARCAYYTNGTN------------------------ ---------------------ATGGGNGARGARGTN------ACNYTNYTNAAYAARYTN GGNGARATHCCNGTNYTNAAYGAYGGNTGGTCNACNGCNGCNGGNTAYTAYTTYMGNYTN MGNGARTAYAAYGCNYTNATGMGNYTNACNYTNTCNATGGCNGARACNAGYGTNAARGTN GCNGGNCARATGTCNACNCCNGTNYTNAAYCAYTAYCARCCNCARATHACNAAYATHAAY GAYTAYGCNTGYAARAARYTNGAYGARYTNGARAGYAARTAYCCNATHATHAARCARCCN ACNGARCARTGGAARGARACNTGYACNGAYYTNGCNGARCCNGTNTTYGTNMGNGTNAAR CCNGTNTTYACNCARGTNCARGGNATHGTNGAYAAYGGNAARCARAARATHGTNMGNYTN AARGARGAYGGNACNAAYAARATHGARGARGCNAARMGNYTNGGNGTNGGNACNATHACN CAYGTNTTYAAYTCNACNTTYGARACNGCNCCNGGNMGNYTNGTNACNMGNACNGTNGAY GGNGCNYTNAAYATGGCNGARGGNYTNGTNGAYAARTAYYTNCCNGARGARAARAGYAAY ATGAAYGAR---------------------GARGARAGYAARTCNGAYGGNGARGAYTCN GAYAAYGAYCAYAARGTNGARGARATGCARGARATGGAYCCNACNCCNCARMGNGTNATH GTNCAYGCNGGNTGYGTNACNCARAARATHMGNAARMGNYTNTTYAGYATHGCNATGAAR GAYYTNACNTAYGCNAARGCNMGNACNGCNTCNGCNYTNAGYMGNATGCARAGYACNGTN CAYYTNATHGAYTAYGCNAARGARAAYYTNGGNACNGCNAARGAYAARGTNGARCARATG TGG------------ACNGAYATHGTNAARGARGARGAYACNGCNGARGARAARACNYTN TTYGCNGGNACNATHGARAAYMGNATHATHGCNYTNGGNMGNACNGTNGCNYTNCARGTN MGNAAYGGNGTNACNGCNTTYGARMGNGCNTCNTCNGARYTNGGNAARTTYGGNMGNAAY CCNATHTCNAARTCNMGNGARTAYAARGARYTNYTNCARACNTTYYTNACNATHGARTCN ATHCARAAYTTYTCNTCNCARAGYYTNGCNAARGCNAGYGCNTCNYTNMGNTTYATHCAR ACNCARATHCARAAYATHGTNAGYGGNTCNGCNTCNATGGAYTGGATGGCNGTNGAYATH GAYATGGAYAAYATHCCNYTNCARGARAAYGAYYTN------------------------ ---CARATHTTYAARYTNAARAARAAYTGGAARGGNATHAARMGNMGNYTNGARGAYACN GGNGTNGARATGYTNATHMGNYTNTTYMGNGTNGCNCCNTCNACNCARGCNCAR------ ---TAYMGNCAYYTNGARACNGARGARAARYTNMGNATGAGYGARGARYTNGARAARCAY GCNGGNAARATGATGTCNACNYTNGAYGAYATHGTNAAYAAYATHGAYGAYGTNGAYTAY GCNYTNGGNCARATHTCNAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARACNGCNTTYGTN ACNGGNGGNGCNCARGGNYTNGGNCAYGGNTAYGTNACNMGNTTYYTNGARGARGGNGCN AAYGTNTTYTAYGGNGAYATHAAYGARACNYTNGGNMGNTCNACNGARGARGARTTYGCN AAYAARTTYGGNAARGARMGNGTNATHTTYTTYCCNTTYGAYGTNACNAAYAGYGAYAAR TTYACNGARGCNTTYGCNAARGCNGTNTCNCAYTTYGGNCARGTNGAYATHATHATHAAY AAYGCNGGNGTNATGAAYGARGGNATHTGGATGAARATGATHCARATHAAYTGYACNGCN GTNGTNCARGGNACNACNYTNGCNATHGAYCAYATGMGNAARGAYAARGGNGGNAARGGN GGNMGNATHATHAAYGTNAGYTCNATGATHGGNYTNAAYGAYCAYCCNTCNGTNCCNGTN TAYACNGGNACNAARCAYTTYGTNMGNAGYTAYACNTCNTCNATGGCNATGACNCCNGGN YTNGARACNGAYATGGGNATHGCNATHGCNTGYYTNTGYCCNGAYGTNGCNGAYACNGAY YTNATHACNAARYTNGAYAGYTCNAARTTY------------YTNGAYTAYGARAARTGG AARGAYAARYTNGARAARGCNATHAAYCCNATHTCNATHATHGTNGAYGGNYTNTTYTCN ATGYTNCAYMGNGARAAY---ATHAAYGGNGCNATHTAYYTNCCNTCNAAYMGNGGNAGY TCNTTYAARAARATGGARTGYGTNGAYYTNGGNGARGARTGGCCNCCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CCNMGNTGGATHMGNAARGGNATGTGYTCNMGNCARTCN CCNGAYTCNTCNTCNTCNTCNTCNTCNCCNCCNTCNTCNGCNTCNTCNTCNTCNTCNATH CCNTCNACNTCNTCNTGYTCNTGGCCNCCNGGNATGCAYTGYGTNCCNGCNAARGARAAR AARYTNAARGTNYTNMGNTGGACNTGYMGNAAYGTNAAYMGNTCNMGNCAYCAYGGNMGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNATGGTNCARGGNTGGAAYMGNGAYACN MGN---------MGNATHTAYGARGARAARGGNTAYACNYTNGAYYTNGGNAAYGARCAR GAYGAYGARTTYGTNATHGARACNACNYTNGTNGAYAAYGARGTNYTNGAYGTNGGNCCN TAYAARCAYYTNGGNTCN---ACNACNGCNAARCCNGTNGARGGNAAYGTNTAYGCNAAR CCNTAYATHTAYAGYAAYTCNGAYMGNGGNGTNACNGTNACNAARAGYTCNGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CCNGGNCCNGGNACN ATGGTNAAYGCNATHGARATGTCNACNAARACNGARGCNCARGTNTTYGGNAARCCNAAY AAYTTYGCNGGNAAYYTNATHTCNCARYTNTAYGGNATHAARGCNGARGARACNYTNATG ATHGGNGAYAGYYTNAARACNGAYATHAARTTYGCNAAYAAYTGYGGNTTYGAYGCNTGY TTYGTNYTNAGYGGNGTNAAYTCNAARGARGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CARYTNGCNYTNGCNCARTCNYTNATHCARCARCARCARYTNAAYATGAAYGCNGGN TTYGCNGGN------GCNGAYTTYGGNTCNYTNGGNGCNYTNACNGGNGGN--------- ATGAAYTTYYTNCARCARCAR------------CARCARATGMGNGGNCCNCCNCCNATG GTNGGNGGNATGGGNGGNATGYTNAAYGAYMGNAARMGNAGYGGNGGNCARYTNAARMGN GAYAGYGAYGGNAARMGNGGNMGNMGNGAYTCNTGGGGNMGNGGNGARMGNGAYMGNTCN ---CAYGGNAAYAAYAGYMGNAGYGGNCARGAYMGNGAYMGNAAYMGNTCNAGYMGNTGG GARTCNGAYAARGARAARAARMGNMGNGGNGARGAYTAYGAYCCNGCNGARCCNACNGAR GAYGAYGAYGARGGNGGNACNAARGGNAAYGAY---TCNAAYYTNTAYTGYCAYGTNTGY AGYGTNTCNGTNTAYGAYGARGARAGYTTYCARMGNCAYYTNAAYGGNYTNAARCAYAAR GCNMGNATGGARAGYATHGCNTCNGCNCAYCARATGMGNTCNACNCARATGACNTCNMGN ATGAARGCNGARGARCAYYTNMGNAGYATHGARMGNAARGGNGGNMGNGAYCCNGAYTTY TTYTGYAARATHTGYAAYAAYGAYYTNGCNATHCCNTGGGARAARCAYMGNTAYTCNAAY ATHCAYAARCARMGNYTNYTNCARGTNMGNAARGGNTGYGGNTGGTGYAARGTNCAYGAY TTYACNAAYTTYACNGARGTNYTNGARCAYMGNGARACNGARCARCAYAARAARAAYTCN GARYTNTAYGGNAARAARGAYGARGAYAAR---GARMGNMGNTCNAGYAARGAYGGNAAR GARGGNGAYMGNACNMGNACNTCNTCNGGNAGYAARAARGAYGARGCNGAYGARGAR--- ------------------------GARGARGARGAYYTNACNATHCCNGARTAYAAYGCN GARAGYGCNGTNGGNYTNGAYTAYGTNATHCCNGTNACNGGNTAYTTYTGYAARYTNTGY CAYAARTTYTAYAAYAARAARTCNGCNAARGCNACNCAYTGYCARACNATGCCNCAYTAY ACNAARTTYAARGARGCNATGGARGTNAARATHGCNGCNMGNGARAARMGNMGNGARGAR GARMGNYTNMGNAARGARAARGARGCNGARGAR---------------------GCNATG GARGARGGNGAYGAYATHGARGARGGNAARGAYGGNGARGARGTNGARGARAAYGGNGAR GAYGGNGAYAARAGYGGNAAYGARGAYGGNGAYCARGAYAAYAAYCARGARGARGAYGAR CAYGAYGAYACNATHYTNGAYGARGAYGTNGAYGARGARGAYGARGGNGAYCARYTNGAY GAYCARGAYYTNTCNGGNAGYGTNGGNGGNGAYGAYGGN---------YTNATHAGYTTY GCNAAYGARACNATGGARAGYTCNAGYTTYATGTAYYTNCCNGGNAAYACNGCNCARGCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARTTYATHGAYYTN GTNTGYCARCAYCCNYTNYTNTAYGAYCCNACNGCNAARCAYAGYGAYGTNCARTCNACN AARACNGTNTGGCARTTYATHTCNTCNGARATGGGNTCNCARCARATGTCNGTNGCNGAY TGGAARAAYAARTGGAARTGYYTNMGNGAYACNTTYGTNAARAARAARMGNGARATHMGN YTNGCNGAYACNCARGARAARATHGARAARCARTGGMGNTTYTAYCAYAAYATGACNTTY YTNGAYGCNCCNATHCCNMGNAGYGGNATHGAYTAYCARCAYTAYACNATHATHAARAAY GAYCARGARYTNGGNGARGARGGNGARGARTAYAGYACNGTNTCNTAYGARAARCARTCN TCNTCNACNACNMGNCARYTNMGNAARMGNAARAARMGNTCNTAYGCNTAYGARYTNGCN GARTCNTCNGCNGCNGGNGCNGAYGGNGARGARGARAGYGARGCNTAYGARGARGARAGY TTYTTYGARTCNTGYGCNTAYMGNATGGAYAARYTNCCNGARMGNATHCARTCNTTYYTN CARYTNCARATHTCNCARYTNTTYTTYAAYGCNGARAAYCCNGAYGTNCCNTCNYTNCCN ATHATGCCNYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN ACNYTNACNAAYCCNGTNTTYMGNTCNTTYATHGGNTAYGCNGCNGTNGTNGTNYTNAAR ACNYTNYTNATGAGYYTNYTNACNACNTTYMGNMGNGTNACNAARAARGTNTAYACNACN GARGARGAYACNACNTAYTTY---------AARYTNAARCARGGNCCNGTNTTY---GAY ---CCNGAYGTNGARMGNGTNMGNMGNGCNCAYCARAAYGAYYTNGARAAYATHATHCCN TTYGTNYTNYTNGGNYTNYTNTAYTCNTGYACNAAYCCNGTNYTNTCNGTNGCNYTNYTN CAYTTYMGNATHTTYACNGCNACNMGNATHYTNCAYACNGTNGTNTAYYTNTTYAARGTN CCNCARCCNGCNMGNGTNATHGCNTTYYTNATHGGNATGATHGTNAAYATGTCNYTNGTN TAYCARATHATGAARCARGCNGCNTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYCAYGCNGCNYTNTAYGARTGGYTNTTYAGY ACNAAYCARGCNGARAARYTNYTNGARATHAAYACNCCNTAYGTNGARCARTAYYTNMGN MGNAARGTNAAYYTNCARGCNGAYAAYACNAGYGCNYTNGAYATGYTNTGGMGNCAYTAY GARAARGTNGARAAYTTYCCNGCNGCNACNMGNATHYTNTCNCARYTNGCNGARMGNCAY GGNACNAAYGTNAAYYTNACNCARMGNYTNGARTAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNAARGAYTTYCAYGTNCCNATHACNATHGCNAARGGNMGNGARAARGTNMGNGARATG TTYYTNAARAAYAARCAYGTNACNGAYATHMGNGTNATHGAYATGYTNGTNATHAARGGN CARATGGARYTNGTNGARACNGCNAAYATHTGGAARCARMGNCAYCAYGTNATGATGTAY TTYAAYGAYACNGTNAAYCCNAARCCNACNGAYTTYYTNAGYAARTTYTAYGARGGNCAR GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGCAYGCN GGNGAYAAYYTNTAYAARAARATGTCNGGNCARTCNYTNTAYAARGAYAGY---GTNGAY CCNGARYTNGAYCAYAARGTNAARMGNGTNTCNGARAARTTYTCNGARACNGTNAAYACN ATHGCNAAYGARCCNTCNYTNGCNTTYTTYMGNATHCARGARCAYGTNMGNAARACNYTN CCNCARYTNGTNGAYACNAARCAYGARGTNGARGAYGTNCARTCNAARGTNCARGGNACN TGYTTYGAYACNGAYTAYGCNATHAAYGCNGTNAARGCNATGCARAGYAGYGCNATHCAY TTYCARAAYATHCARGAYYTNYTNAARAAYGCNATGTTYATGAARCARCARATHTCNTAY GARGAYAAYMGNMGNAARCAYGGNMGNAGYAGYCCNATGACNGGNGARMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GAYGGNMGNAARGARAGYYTNYTNGCNTTYGCNAARGCNATGGARGARATHATHCAY GGNATGGTNATHTTYGCNAARGTNATHCCNGGNTTYTCNAARYTNACNACNGARGARAAR ACNAAYYTNATHAARTAYTCNMGNCARGARTTYTAYTTYYTNAAYYTNTTYAARTAYGTN AAYYTNGARYTNAARACNTAYAARGGNCCNGARMGNTGYTGGCARTGYTCNYTNGAY--- GARAAYTCNACNYTNMGNCAYAAYYTNGAYATHACNTAYCAYTTYYTNGCNAARTTYCAR CARATGAAYYTNACNTAYACNGARTGYGTNYTNYTNCARGCNTCNGTNATHATGGCNCCN GAYMGNTCNAAYCCNGTNACNATGTCNGCNATHCCN---GCNATHTAYCAYGARYTNGTN GAYYTNYTNGTNTAYGARYTNAGYAARMGNATGGAYMGNCCNATGYTNCAYTTYGCNAAR YTNATGGGNYTNATHACNGARTGYMGNACNAARGCNGAYGAYYTNACNGCNATGTTYMGN MGNGARGAYTAYATHMGNTAYACNCCNATHGARGAYAARCCNTTYYTNCARGARATGTTY GCNGGNATHTAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MGNGTNCCNTCN ACNGARCARGAYTCNAARTTYTTYAAYAAYGTNCARAAYGARGCNAARCARATHYTNMGN CARGAYAARATHCARGARGAYTAYMGNAARGCNTAYGCNGCNGAYAAYGCNGTNGTNGCN AARYTNAARAAYGAYATHGARGARMGNGAYAARACNATHGCNGARYTNAARGGNCARGTN GARAARATGGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------MGNTAYGARTGYYTNTAYTGYACNGARCAYTTYTCNCAYAGYACN YTNGCNGGNATHAARCAYCAYTAYGCNGCNGARCAYCCNGGNCARYTNYTNGTNGTNMGN GAYGTNGARGCNAARAARGARAARYTNGCNTCNMGNATH--------------------- ---------------------GARGGNCAYGAYATHGTNGCNYTNGCNAAYYTNMGNCCN GARAAYAARGAYGARYTNGAYAGYTAYATGTAYCARACNGTNGGNCAYCAYGCNATHGAY YTNTAYTCNGARGCNATGCARYTNCCNYTNTAYGTNMGNACNATHAARGGNTCNAGYYTN TGYGTNAARCARGAYTAYYTNCCNGTNGARGGNGAYGARGTNGARGAYYTNTAYCAYYTN YTNTCNCARATHAARGTNGARMGNGAYATHGAYGCNGTNAGYGTNGGNGCNATHYTNTCN GAYTAYCARMGNGTNMGNGTNGARAAYGTNTGYCARMGNYTNAAYYTNAARGTNYTNGCN TTYYTNTGGMGNMGNAAYCARGARGAYYTNYTNMGNGARATGATHTCNTGYGAYYTNMGN GCNATHGTNATHAARGTNGCNGCNYTNGGNYTNYTNCCNGCNAARCAYYTNGGNATGGAR YTNAARGARATHTTYCCNCAYATGYTNAARATGAARGARMGNTAYGGNYTNAAYGARTGY GGNGARGGNGGNGARTAYGARACNTTYGTNTTYGAYTGYCCNYTNTTYAARAARTCNATH GTNATHGARGARAARGARYTNGTNATHCAYTCNGAYGAYGCNTTYGCNCCNGTNGGNTAY YTNAAYYTNAARAARTGYCAYYTNCARGARAARCCNGGNTAYGAYGTNGCNTCNTTYYTN AARAAYGTNGAYAARTTYCCNATHACNACNACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYCARGTNGTNGGNYTNGGNAAYCAY CCNTAYCCNGAYACNMGNCAYAGYATHGGNATGACNGCNGTNGAYMGNYTNGCNTTYMGN YTNGGNYTNCARTGGGARAARATHCAYGGNAARCAYGGNGGNTTYTTYTGYAARACNGGN ATHGARGCNACNGARAAYAAYGTNGCNGARGTNTTYYTNTTYAARCCNMGNGCNYTNATG AAYATHAGYGGNGGNAAYGTNGCNAARACNGCNTCNATGYTNGGNGTNAGYGCNGAYAAY GTNTAYYTNGTNCAYGAYGARYTNGAYATGGCNATHGGNAARTGYGGNYTNAARGAYGGN GGNAGYGCNAARGGNCAYAARGGNGTNCARTCNTGYGTNYTNTCNTTYAARTCNCAYGGN ATGTGGCCNAARGARAARGGN---------------------------------ATGCCN MGNYTNMGNATHGGNATHGGNMGNCCNTTYTCNAARTCNCARGTNGTNTCNTAYGTNYTN AGYCCNGTNCCNTCNCAYGARATGAARTCNATHTCNACNGCNATHGAYCARGGNATGGAY YTNGTNYTNAARCAYATHACNGCNMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CARMGNAARYTNAARGARAARGCNMGNAARGARGARGARTCNGARATGGGNGAYGAY GAYGAYTTYGAYGTNGTNGARGAYGAYGARGGNMGNCARCCNACNCCN---AARYTNAAR GARAARACNTCNGGNTCNMGNCAYCAYYTNGAYYTNACNACNCCNGCNGTNGGNGGNGCN YTNYTNACNTGYCCNCCNTCNAARAAYAAYAARATHATHGTNACNTCNMGNTCNGGNGAY AGYTAYGTNACNGCNTCNGAYAAYATGGARGTNCCNCARGTNCAYAARAARATHGAYATG GARAAYYTNAAYACNMGNCCNATHYTNGGNCARCCNTCNGGNGAYAGYCAYGCNYTNMGN GAYGAYGAYGCNTCNACNGAYMGNGCNYTNAAYACNMGNTAYGTNCCNTCNCCNGCNYTN ATHAAYAGYGAYGARGAYAARGARAAYAGYAAYAARAGYAARAARTCNAGYAARACNTCN AARCCNAGYMGNYTNACNCCNGTNCARGARGGNGCNGGNAARACNTTY---CAYTCNAAR GCNTTYYTNACNYTNGAYGAYATHAAYGARGCNAARGGNCAYAAYGTNGAYGARGAYGTN ATHTCNGTNTCNATGATGTCNGTNGCNTCNAGYGCNTCNYTNGCNTCNGARGTNYTNGAR MGNGCNMGNMGNMGNCARAARGARTTYTGGGGNAARGGNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TAYYTNGGNGARAARGTNGGNGCNGGNCAYATGTGYYTNTGGTGYAAYGARAAR GGNAARMGNTTYCAYAAYAGYMGNGAYGTNCARMGNCAYATGGTNGAYAARGGNCAYTGY AARATHYTNCAYGTNTCNGARACNATHTAYGARTTYGCNGAYTTYTAYGAYTAYTCNAAR AGYTAYCCN------GAY---GCNGAYGGNGARAAYCCNCCNGAYCCNGARTCNGTNGAY ATHATGGARYTNGAYGGNGAYGGNTAYTCNGTNACNYTNCCNTCNGGNTCNGTNATHGGN CAYMGNTCNYTNATGMGNTAYTAYMGNCARAAYYTNGTNCCNCARATGMGNGARMGNACN AGYAAYGCNYTNCCNAARATGYTNGCNCAYTAYAARTCNYTNGGNTGGACNGGNGCNACN GGNACNCARGTNGARCARMGNGCNAARGAYYTNCAYTAYATGMGNMGNYTNMGNAGYMGN CAYTAYATGCARYTNGGNGTNAARGGNAAYAAYYTNMGNCAYMGNTTYMGNGAYTCNAAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYGAYYTNGTNYTNTTY ATGCCNGTNYTNYTNGARYTNACNTCNGCNATHGGNMGNTGGTTYCCNTCNAGYACNCAR ACNAAR---------AAYGTNGAYACNAARATHACNACNCARAARATHGCNTCNGTNGTN TCNTAYYTNGARGARTAYGTNAARYTNAARMGNATHGCN------------GAYGGNAAY YTNACNGAYGAYGAYGARAGYYTNAARAARGARMGNACNCARGARGARATHGARAARGAY TTYCARAAYYTN------------MGNAARGARMGNGARAARGARAAYGAYAGYGARGCN ATGGARGARGARGGNGARGAYGARGARGARAARCARAARGARTGYCCNAARCAYATHCAR GTNGTNAARGARATHYTNTCNMGNGTNAARAAYYTNYTNTCNTCNCAYGAYGCNMGNGTN MGNGTNCARTCNYTNGARATHGTNGCNCARGCNTGYAARGAYYTNGCNGAYCAYGARMGN GARYTNYTNCCNCARATHCAYCARATHTGGCCNGGNTTYTAYCCNMGNTTYCAYAGYGAR GARAARTTYGTNATHATHAARGCNYTNTGYAGYYTNMGNGTNATGGCNGAYGTNGGNGGN AGYTTYATHCARCAYMGNGTNATGAARGAYGTNGTNCCNTGYYTNTCNCARTAYATGGAR AARCARGCNAAYATHAGYTGYGARAGYMGNTCNACNTAYATHAAYACNGCNAGYTTYAAR YTNCARYTNGCNATHYTNGAYACNYTNGGNCCNYTNGCNGARMGNYTNGARGTNAARGAR CAYAGYYTNGAYACNGTNGCNAARATHTGYYTNCCNTAYYTNAGYGAYYTNCARCCNYTN AARYTNCARAARGCNAGYGTNTCNGCNTTYTCNTCNTTYATHTCNYTNGAYCCNGAYGCN ATGTGGYTNYTNYTNTGYCARGTNTAYTGYCCNTGGCARTAYAAYYTNCCNGGNAAYGAR TTY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AGY GAYYTNGTNATGGAYTTYGARGTNGGNGAYATGGAYGARGAYGARGCNGGNGARTCNACN YTNGTNATHGCNGARACNGARAARAARAARAARAARAGYACNGGNAARAARAARGGNCAR AARGARAARGAYGARACNACNCCN---AARGARGARAARCCN---AARAARATHCCNAAR MGNGCNCCNACNGCNTAYATGYTNTTYTGYAAYACNCAYMGNCCNTCNATHGTNCARGAR AAYCCNGGNATHGCNTTYGCNAGYATHAGYMGNAARYTNGGNGARYTNTGGCARACNCAR TCNAAYAARCARAARYTNCARTGGMGNMGNAARGCNCARMGNMGNATGAARAARTCNAAY YTNATHTCNACNGGNAARGCN---TCNACNGCNGCNGCNGAYGTNTCNCARGGNGCNGCN ACNYTNAAYTCNACNAAYCAR---------------AARYTNGCNYTNATGYTNCARAAR AGYAARACNGCNGCNGCNGAYGARGGNCCNYTNAGYCCNACNAARAAYTTYAGYATHGAR CCNYTNGAYGTNGCNGCNCAYYTNAARYTNYTNGGNGARTCNYTNAGYATHATHGGNATG MGNYTNCARGARCAYAARGGNATGATHGCNGTNCARGGNAGYYTNTCNGTNYTNYTNGAY TCNYTNYTNTGYGCNTGYGGNCCNYTNYTNTGYYTNACNCARCARGTNCCNGGNATGGAY GGNTGYTCNCCNYTNGTNCAYGCNAARACNYTNGAYAGYATHGCNTAYGTNATGCCNGGN YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CAYAARGARGGNTCNMGNTAYAGYCCNACNCCNGAYYTNGCNATHGTN ACNCARCCNAARMGNYTNGGNGAYAARAARAGYGAYTTYYTNMGNGCNATHMGNAAYGAR AGYTCNGTNMGNAAYGGNGARGTNTGYCARAAYCARAAYCARAAYGTNGARMGNAARGGN GARTCNAARCARGAYAAYAAYGARAAYCCNATGTAYCAYAAYATGAAYGGNGARMGNCAY GTNGAYACNAAY------GARAAY---------------TTYGTNTGYGTNAARACNGGN GGNYTNAAYGGNGARATGCARGAYGCNATHAAYGGNGAY---------GCNYTNATHAAY CAYGTNGAYCAYATHTCNYTNTCNGGNGARGAYGARGARMGNMGNYTNYTNYTNYTNATG GGNTGGGARGARGARGAYAAYACNGARTAYGTNATHACNGARGAYGARATHMGNGARTTY CARAAYYTNGTNCARAARAAYTGYCAYGGNCARAARAAYGGNYTNAARTCNTCNYTNMGN AGYGCNYTNGAYMGNAARTTYGGNGCNGAYAAYATG------YTNAAYGGNATHCCNTCN GARGARGARAARATHGAYAARAARYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYGGNMGNTAYCCNMGNGARTAYAAYCCNAARGTNCAYGGN CCNTAYATGCCNGGNMGNTTYTAYGGNAARCCNGAYACNCCNGTNGGNGARGTNAARYTN GGNGARYTNGGNTCNTGGTTYGGNMGNMGNAAYAARAGYCCNCARGCNATGTGGGCNTGY GTNCAYMGNGCNTAYTGGMGNTGGGCNGCNAAYAAYYTNCAYGTNMGNCARAGYGGNTTY AARCCNATHGGNCARGCNGCNATGGTNATGTCNTTYACNTTYTTYYTNYTNYTNCAYAAR GARMGNAGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARATHGCNMGNTAYGAR GAYACNYTNGCNCARYTNCARACNGAYCARGARAARYTNCARGARCARTAYMGNCARTCN TCNTCNAAYYTNATGGARGCNGAYAGYAARGTNCAYGARYTNAARGTNCARYTNACNACN YTNCARGGNCAYCAYAARGARGCNATGGAYCARYTNACNGAYAARGCNMGNCAYYTNGCN GCNATHAARACNGARGCNGCNAARATGGCNCARCARAAYAAYTCNATGAARGAYGARATH ATGATHTAYGAYGARAARGTNMGNAARYTNCARCARGARYTNMGNAARTCNCARGARYTN AAYAARGCNACNGARGARGARYTNCARCAYTTYGARGARMGNTAYACNAGYYTNCARGTN GAYYTNGTNGCNAGYCARGARAARCARAARCARTCNYTNCARGARYTNTCNTCNAAYGAR GARGARATGGTNGTNGTNAARGTNGARYTNAGYTCNYTNCARGARAARTAYAARGCNTCN AAYGAYGARGTNCAYAARYTNACNAGYGARYTNGARYTNACNAARCARAAYTAYMGNAGY GCNACNGARGARATHTCNGGNYTNMGNGTNGCNYTNGARGARTCNMGNGCNAAYGGNGAY MGNYTNCAYMGNGARAGYGARYTNGTNGTNCAYAAYGTNAAYACNTGGGTNCARGARCAR AARYTNGCNAAYGARAARYTNGGNAAYAARATHMGNGAYCARAGYAARTCNATHATGGCN YTNACNTCNGARAARGARAAYYTNYTNGAYCARGTNGCNAARYTNCARAARAGYTAYAGY AARACNMGNACNGARYTNGARGAYAARGGNYTNGARGCNGARAARYTNMGNGCNYTNCAR TCNCAYTCNGTNCAYCARCARGTNGTNYTNAAYCARYTNAARAGYMGNYTNGARGARCAY GARYTNGAYAARGAYCARGAYYTNAARACNAARGTNGCNACNATHGARGAYYTNCAYCAY MGNYTNAARTCNAAYATHGARAGYATHCAYCARYTNAAYCARCARYTNAGYACNYTNCAR AARGAYAAYATHMGNYTNMGNAGYGARYTNGAYMGNGARATHGCNACNMGNCARAGYYTN GARATGCARATGCARAGYAARGAYCARYTNGTNGARAGYYTNMGNACNCARYTNGAYTCN AAYTCNTAYAARCAYYTNYTNGARAARGCNGARAGYTAYAARGAYCCNGARAARYTNACN MGNTCNGCNTTYAGYAARGCNACNGARGAYGCNGGNGTNCCNGAYCCNCARAAYYTNGAY AARTCNTAYTGGATHACNMGNGTNGGNGAR------YTNTCNATHCARYTNCARCARAGY AGYGAYTAYTGGTCNGAYAARGTNMGNGAYYTNTCNGARCARYTNGARAARGCNMGNAGY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNATHATHTGYATGAARYTNGAYYTNYTN GARAAYGTNGARATHYTNAARGCNCARCCNACNYTNTCNCARGGNMGNTAYMGNYTNYTN CCNGAYTCNGARMGNCCNTCNYTNAAYGAYGTNGCNGGNGARATHGCNGTNAAYGARTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GAYATHGGNGAR ACNATHGCNCARMGNMGNMGNMGNGCNGGNGTNTAYAARAAYAAYTCNGGNCCNCCNCCN GARMGNMGNAGYACNATHAGYACNATGACNAGYAAYAGYAGYTAYCARGTNACNMGNATH MGNAAYYTNTCNGGNGGNAGYAAYGGNAGYACNGCNAGYGGNAGYAGYAGYGGNAGYTCN ACNCARYTNGAYAAYCARTAYTCN------ACNGAYAAYCARYTNTAYTTYCCNYTNGAY ATHTCNCCNTTYGCN---AAYTCNAAYGCNGAYCCNCAYCAYMGNGAYGAYTCNYTNTCN TCNTCNCAYMGNAARYTNGAYMGNAGYYTNAGYGAYAGYGAYAGYGARMGN------TCN GGNCAYGTNTCNTCNCAYAARTCNGTNAAYTCNAGYMGNTAYAARACNGARYTNTGYMGN CCNTTYGARGARAGYGGNTCNTGYAARTAYGGNGAYAARTGYCARTTYGCNCAYGGNTCN CAYGARYTNMGNAAYYTNGCNMGNCAYCCNAARTAYAARACNGARYTNTGYMGNACNTTY CAYACNATHGGNTTYTGYCCNTAYGGNCCNMGNTGYCAYTTYATHCAYGARGAYGAY--- ---AARAAYGAYGGNGCNACNCCNAAR--------------------------------- ---ATHACNGARAGYGGNAGYAGYAGYCCNTCNYTNAGYCCNACNGGNAAYGAYAAYAAY ---------TTYTCNTAYTGYTCNGARTCNACNTCNCARATGAAYATHGARAAYGCNCAR ATHAAYAAY------TCNYTNACNGTNCAYATHAAYAAYTAYAGY--------------- GAYYTNCARTCNYTNGAR---CARCAYTTYAAYTCNGCNYTNAAYYTNAAYMGNAAY--- TGYAAYGARTCNTCNMGNAAYGTNYTNAAYTCNAGYTGYAARACN--------------- ---------------GARGARTAYGAYATHTTYAGYTCNATHTCNGTNTTYAAYGCNGAY GARGTN---GTNGAYAAYGCNCCNAAR---CCNTCNAAYTCNTAYTCNTCNTAYTCNAAY AARCARACNYTNGAYAAYTAYCCN---ACNTAYGTNGAYACNAGYTGYTTYTGGCCNTCN AGYGTNTCNTCNTCNCARAAYATG---GCNCCNGTNGAYCCNTTYCAYTAYTCNCCNACN GGNTCNACNGGNTCN---AGYTCNTCNGGNTCNGAY---TCNGGNAGYAGYAGYGAYTGY AGYGGNAGYACNGARAGYYTNGTNAGYTCNGGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY CCNCARCCNACNGCNTGYTGYAARCCNYTNMGNTTYAARGAYTTYATHATHTCNTAYGAY TCNMGNAAYMGNATHCCNAAYTGGGTNTAYGARCAYYTNAAYAARTTYAAYYTNTTYAAY GARGAYCCNTGYAAYCARATGAARAARATH---AGYMGNCARGAYAARGAYMGNCCNAAR TTYACNCCNGAYTGYMGNATHCAYGGNTAYCAYMGNGCNGAYGCNAARGAYTAYTGYGAY ACNGARTAYGARATGGGNYTNATGGCNAAYCCNGARAAYTAYCCNTTYTGYCARGARGCN TAYTGYGARGGNTTYACNATGACNAAYGTNGTNCCNCAYGTNCCNGGNTTYAGYTGYGGN CCNTGGTAYGAYYTNGARACNTAYATHMGNGARAARYTNGTNMGNAGYAAYAARAGYGTN TAYATHTGYTCNGGNCCNYTNTTYYTNCCNGTNGARGAYGGNGAYAARATGGTNAARTGY TTYGAYGTNYTNGGNGAYGGNGARGTNTCNGTNCCNACNCAYTTYTTYAARGTNATHGTN ATHGARACNGARGAYGGNCARYTNGARYTNGARACNTAYATGGTNCCNAAY---GCNCCN GGNGAYGGNAAYGARACNAAYYTNGAYGAYTGGYTNACNCCNYTNTGYCARATHGARCAY CAYTCNGGNYTNATHTTYTTYCCNGAYAARAAR---TGYTTYAGYAGYAAYAAYAARMGN MGNGGNGCNAARYTNCAYGCNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARACNTTYCAYGTNATHCCNYTNCCNCCNCCNYTNGARGAYAGY GTNTTYGTNGGNMGNMGNGAYGTNMGNAAYCCNCARTCNGTNCCNGARAARAARATHATH AGYGARAARGGNACNGTNMGNGGNTTYACNAAYMGNGTNMGNGCNGGNATHGCNACNTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATHACNGGNYTNYTNATHGTNGCNACNACNAAYTCNATHTCNAAY GTNGAYCCNMGNYTNMGNMGNCCNGGNCAYTTYGAYCARGARGTNYTNATHAAYGTNCCN ACNCARACNCARMGNATHTCNATHYTNMGNGTNYTNACNGCNGAYYTNAGYYTNGCNTCN AAYGCNTCNTGYGARACNYTNGCNCARATGACNCCNGGNTTYGTNGGNGCNGAYATHMGN GGNYTNTGYGARGARGCNATHAGYCAYTCNCARTCNTCNCARGARTCN------------ ACNGARATHACNATGGAYGAYTTYAAYTAYGCNTTYCAYAARATGATHCCNTCNYTNAAR AARGGNATGGARTGYGTNGTNGAYYTNAARCCNGTNGCNTGGTCNGARATHGGNGGNYTN CAYGARGTNAARTCNGARATHAARCARTCNYTNGARTGGCCNYTNAARTAYCCNGARGTN YTNMGNMGNATGGAYATHCCNCCNACNAAYGGNATHYTNYTNTAYGGNCCNCCNGGNTGY TGYAARACNACNYTNGTNMGNGCNGCNGCNACNTCNTGYAAYGTNTCNTTYYTNTCNYTN AGYGGNGCNCARGTNTAYTCNGCNTAYGTNGGNGARTCNGARMGNYTNATHTCNAARGCN TTYCARAARGCNMGNGCNYTNGCNCCNTCNATHYTNTTYYTNGAYGARATHGARTCNYTN GTNGGNAARMGNAARGCNGAYGTNGGNCARAAYMGNGTNCARGARMGNATHYTNTCNACN ATGYTNAAYGARATGGAYGGNGTNGGNAAYMGNYTNGAYTTYAARYTNTGYTCNTCNYTN TCNGARGAR---------------------ACNTCNAGYAAYTCNGGNATGCARMGNACN TTYGARTAYACNGGNGARAAYGCNGAYATHCCNGARAAYTCNAARGAYTCNGGNACNAGY AAYAGYYTNMGNGTNATGGTNGTNGGNGCNACNAAYMGNCCNGAYATGYTNGAYGCNGCN ATHYTNMGNCCNGGNMGNYTNGAYAARCAYATHTAYGTNCCNCAYCCNGAYGARGARGCN MGNAARGCNATHYTNCARATHTAYACNTCNAARATGTCNAGYAGYGAYATHGAYYTNAAY YTNYTNGCNGCNACNACNGAYYTNTAYAGYGGNGCNGAYYTNATGAAYYTNTGYAARGAR GCNGGNYTNCARGTNYTNMGNCARCARYTNTTYCAYTCNGARAGYCARAAYGAYYTNACN GTNTCNCAYCAYCAYTTYCARCARGCNYTNGAYAARGTNAARCCNTCNYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AARATHGCNYTNGCNCARGGNCARCARYTNGAYATG GARGARGARYTNGARGARATHMGNGTNGARATGACNAARGAYMGNGCNYTNGCNYTNAAR GAYCARGARGARMGNYTNGGNGCNYTNATHGCNTCNYTNCARATGGAYAARGCNMGNGAR YTNGCNAARATHGARGARCARCARMGNGCNATHAAYAAYYTNAARTCNAAYYTNATGGAY GAYYTNAAYGCNMGNGGNATHYTNTCNACNCCNGARTGYCARAARATHYTNAAYATHCAY AARGARGARCARGAYACNATHAAYCAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ACN CARACNATHGAYATHTAYCARGGNTCNMGNACNCARYTNATHCARYTNCAYGAYYTNYTN GARGGNMGNAGYTAYACNATGTTYYTNACNTGYGAYGGNACNATGAARACNAARGARGTN AGYTTYGTNGTNGGNGAYYTNTGYGGNAAYGGNGAYMGNCAYACNTTYATH------AAY GTNACNACNGCNAARGCNGAYGAYCCNACNAAYTCNGTNCARATHTAYAARACNAAYGTN AGYGCNGTNGAYTGGYTNAGYGCNGTNATHTTYTCNTGYYTNGGNGTNACNYTNATHGCN GTNGTNGGNTAYTAYACNTGGAARAARTAYCARCAYMGNMGNMGNATHYTNMGNATHTTY MGNCAYGARCARAAYGAYCCNTTYCARGCNYTNTAYAGYCCNAGYCARGAYTCNTAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYTTYGARTCNTCNGAR YTNGGNACNCARAARCAYTGGGAYGAYGCNTAYCARAARGARYTNGARAAYTTYACNAAR YTNGGNATHGCNGGNGARATHTGGTTYGGNGARGARAGYCARGAYMGNATGGTNMGNTGG ATHTCNGARAARTCNAAYYTNCCNYTNTCNGCNAAYATGATHGAYYTNGGNTGYGGNAAY GGNATGYTNATGYTNGCNYTNMGNGARGARGGNTTYACNAAYYTNACNGGNGTNGAYTAY TCNAARTAYTCNGTNCARYTNGCNCARAARATGGCNGARTCNGARGGNGTNAAYGAYYTN ATHTTYGARGARTGYGAYATHYTNTCNCCNGAR------GARGCNAGYAARMGNAGYGAY YTNTAYGAYGCNTGYYTNGAYAARGGNACNTAYGAYGCNATHAGYYTNAARGAYACNACN GAYCCNACNGAYMGNAARYTNTAYATHMGNCAYGTNCAYTCNATGYTNAARGCNAAYGGN YTNYTNATHYTNACNTCNTGYAAYTGGACNAARAGYGARYTNGARCARCAYTTYTCNCAY GAYTTYGTNYTNACNCAYGARATHCCNGCNCCNAARTTYACNTTYGGNGGNCARACNGGN CARACNGTNACNTCNGTNATHTTYACNMGNAARGCNCARATHATHGTNTTYCCNGARGAY GGNYTNTAYGGNAGYGAYTTY---ACNMGNAARTCNATHTTYCCNTTYYTNGARAARATH CCNGAYCAYAARAARGCNMGNTGGTCNCCNTGYTCNCARCCNGGNMGNTTYMGNGAYACN CCNGTNCARAARGCNYTNAGYTGYATGGCNCARGARAAYAARATGTAYGTNGTNGCNAAY ATGGGNGAYATGGTNCCNTGYAAYMGNTCNTCNGAYCCNAAYTGYCCNTCNGAYAAYCAY TAYCARTAYAAYACNAAYGTNGCNTAYGGNCCNGAYGGNACNYTNYTNGCNAARTAYCAY AARACNCAYYTNTTYTTYGARATHCARTTYGAYCCNGCNAARCCNGARGTNGTNTTYTTY GAYACNCCNTTYGGNMGNGTNGGNATGYTNATHTGYTTYGAYYTNATHTTYAARGAYCCN TCNGTNGAYATHGTNACNAARTAYAAYATHACNAAYATHGCNTAYTCNGTNGCNTGGATH GAYTTYYTNCCNYTNYTNTCNGCNATHGGNTAYCAYTCNTCNTTYGCNMGNGGNYTNGGN GTNAAYGTNYTNACNGCNAAYYTNCAYATHCCNTCNGGNMGNTCNCAYGGNAGYGGNATH TAYACNCCNAARGGNATGTCNGCNTTYTAYTAYGAYAAYGAYAAYYTNTCNCCNGGNAAR YTNYTNGTN------------------------------TCNACNATHACNTCNYTNCAR CARCCNAAYYTNGTN------------ACNYTNMGNGCNAARCCNATGACNCARAAYTCN AAYGAY------------------------------------------------------ ------------------------------------GTNAGYGAYGARTTYGARTCNATH ATGTTYCAYGAYAARTAYACNTTYAARYTNYTNAGYGAYTCNACNGGNGARYTNAAYGTN TGYCARMGNAAYGTNTGYTGYTCNYTNGARTAYAGYTTYGTNAAYCARACNTCN---MGN GAYYTNTTYGCNTTYGGNGCNTTYGAYGGNYTN------CAYCAYGGNCARGCNTAYTTY CARACNTGYGCNYTNGTNAARTGY---------GCN---AAYCAYMGNACNTGYGGNTCN CCNGTNAGYGTNTCNTCNACNAAYTTYAARTCNTTYTCNATHACNGGNCAYTTYCARACN AARTTYGTNTAYCCNCARGTNATHYTNAGYAARTCNGGNCARYTNGCNYTNGCNGAYCAR AAYTCNTGGAGYTTYGARAAYAGYAARYTNACNACNTCNGGNTCNAGYYTNGGNTCNCCN GTNYTNTCNGCNGCNYTNGTNGGNMGNTAYTAYMGNMGNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CAYNNNYTNACNTGYGARGCNNNNAAYCCNGCNGAYACN GGNAARACNGTNTCNNNNNNNMGNNNNTCNNNNGTNGTNNNNNNNCCNCCNNNNYTNCCN CCNTCNATNACNATNGAYAAYGGNNNNNNNGTNNNNGAYATGAGYGANCARGTN---TTY CARNNNGGNCARNNNYTNGAYATHMGNTGYTCNGTNNNNGGNGGNTAYCCNNNNGTNAGY AAYGTNNNNNNNGANTGYACNNNNNNNNNNNNNNNNNNNGGNNNNNNNNNNNNNNNNNNN YTNACNTCNYTNACNGTNAAYAARACNATGNNNCARAAYNNNTGYACNTGYNNNGCNTCN CAYNNNNNNNNNTGYTAYAAYAARNNNACNCARTTYACNNNNNNNNNNMGNTAYNNNNNN GANNNNNNNAGYTTYAAYTCNCARGTNCARCARMGNTGGACNAAYYTNMGNAAYTGYTTY YTNMGNGARYTNMGNGARCARAARMGNAGYGTNTCNGGNCARGCNGCNAARAARMGNMGN AARTAYATHTAYTTYGAYCARATGYTNTTYYTNYTNCCNACNYTNGGNGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNYTNGAYGAYTTYATHMGNCARAARAAYGTNAARGTNCARATHMGNAAY--- ---ACNGCNCARCCNMGNGGNCARGTNCARMGNAARACNACNGCNGTNAAYAAYAARTTY CCNAAYAARCCNGTNCAR------MGNACNTTYGAYGCNMGNTCNAARYTNGGNCCNAAR TCNGTNACNGAYGCNMGNAAYAARATHATHATHAAYAARAARAAYGGNAARGGNGAYGCN MGNAAYAARATHGTNCARAARCARGTNCARAARGGNACNTTYGAYGCNMGNTCNYTNYTN AARMGNACNGCNAARAARACNAAYGGNGCNAAYAAYCCNCARGGNCCNCARATGAAYCCN CCNGGNGTNCARCAYATH------------------------ACNMGNACNYTNTCNAAY CCNATGACNATGGGNCARATHGGNAAYTTYCARATHACNMGNCARATHCCNGGNACNGAR GTNACNYTNTCNMGNGAYTCNYTNCARGTNACNAARAAYGTNYTNGGNGGNCCNCCNCCN ATGACNCCNATGGGNGARGCNGTNCCNATHATHCARATHMGNAAYGAYMGNTAYMGNCAR GARATGCCNCCNCCNCARCCNGGNTGGTCNAAYCARTTYCCNCARMGNYTNCCNCARCCN CARTAYCCN------------CAYCAYAAYCCNTCNTAY--------------------- ------------CCNCCNCCNAAYCCNTCNCARCCNMGNTAYCAYGAYTTYGAYAAYCCN GARYTNAAY---AARCCNCCNYTNAGYGTNCAYGARATHCCNAARATGCAYATHTCNAAY ATHAARGCNGTNGARGCNGCNGGNATGMGNCCNGTNTCNTCNMGNCCNGCNCCNYTNCAR ---------------CCNMGNGTNCCNCCNGGNGCNGCNACNYTNTCNGCNAARCARCCN ATHGGNYTNTCNCARTCNTCNTCNATH---------------GGNYTNAARMGNMGN--- CARCCNCCNTCNCARGARGTNGGNGGNCCNYTNMGNYTNGGNAARGGNGGNGGNCCNGGN YTNCARGTNGGNATHGGNGARAGYTCNCCNCCNAARAARGCNAAR------TCNGGNATH YTNGCNTCNGAYCCNATHGARATHATHGAYYTNGARGAYACNTCNAARTTYGTNAGYCCN YTNCARGGNTTYMGNGTNGTNGTNACNAAYYTNTTYTCNGGNGTNACNCARGAYGAYATH ATHGARYTNTTYGGNGTNGTNGGNCCNYTNAARAARGCNMGNYTNYTNAARGCNGGNTCN GCNGARGTNGTNTAYTCNATHMGNGARGAYGCNATHAARGCNGTNCARAARTAYCAYGGN MGNGARYTNGAYGGNCARCCNATGTAYGTNAARATGACNACNCCNTCNGCNGCNGTNGTN AARACNCCNCARGGN---ATHGAYCCNGAYATHACNGGNGARGCNYTNMGNYTNTAYAAR AARCCNAGYAGYYTNGGNGCNYTNCCNGARGCNCCNATHGARGTNCCNACNATHCAYMGN GCNYTNTTYAARGTNGGNCCNCCNGCNCCNAAYAARTCNGTNAARTTYACNGTNAARATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNGTNTGYACNGTNTAYYTNYTNYTNGGNYTNYTNATGAAYTGYGTNGAYAGY AARAARTCN---CCNGARTGYTCNACNTGYAARGARATHGTNGARAAYTTYCAYAARGGN YTNTCNGAYACNGAYAARTCNGGNTAYGGNGGNGGNAAYACNAAYTGGGARGARAARTCN YTNGGNTCNTAYTGYCAYAGYGARGTNMGNYTNACNGARATHATHGARAARYTNTGYGAR GGNAARTCNAARGARTGYCAYACNYTNYTNGARGARCAYGARGARYTNGTNGARACNTTY TGGTTYAARCAYTTYACNCARGGNAARMGNACNGAYTTYYTNACNTTYYTNTGYATHGAR AAYATHCARGCNTGYTGYCAYAAYAAYACNTAYGGNAARGAYTGYAARGCNTGYCCNGGN GGNGTNGAYAAYCCNTGYCAYGGNAAYGGNAARTGYGAYGGNGCNGGNACNMGNAARGGN ACNGGNAARTGYCAYTGYTCNGCNGGNTAYACNGGNGAYYTNTGYACNGAYTGYMGNGGN GGNTAYTTYAARGCNAGYAARAAYGAYACNCAYGAYGTNTGYAARGTNTGYCAYATHTCN TGYAARGGNAAYTGYTCNGGNGARGGNCCNAARGCNTGYGARGARTGYAARGAYGGNTGG GARYTNAAYGAYAARGAYGGNTGYCARGAYATHAAYGARTGYYTNGAYGARCCNTGYGAR GAYAAYCARTAYTGYACNAAYACNCARGGNTCNTAYACNTGYTTYAGYTGYGAYTCNGCN TGYGTNTCNTGYACNGGNGCNGGNCCNCAYAARTGYAAYGAYTGYAARGARGGNTAYAAY AARYTNGARGAYGGNAAR---TGYGARGAYCARGAYGARTGYATHGCNGAYTCNAGYYTN TGYACNAARYTNAAYGARGARTGYGTNAAYACNCCNGGNAGYTAYAARTGYATHTGYTCN TCNGGNTAY---GARTAYAARGAYAAYGARTGYGTNAARGTNCCNGARGAR--------- ------------------------------------------------ATGGGNATHTCN GARAGYAARMGNMGNGTNGTNGTNGARGAYGTNAAYGGNGARGGNGTNGTNCARGTNACN GAR---GCNGTNGTNMGNMGNGTNAARGGNTCNGAYACNCCNCCNCCNGTN--------- ------------------------------------------------------------ ---------GAYGARATGTTYCARACNATHGARGGNTTYTAYATGGARAARYTNAAYGAY YTNCARAARMGNAGYGARCARYTNCARCARCAYACNAAYGARCAYTTYGCNAAYGCNGTN AARGARGTNGARCARAARTTYATGAARTAYACNTCNTCNCCNGTNTGYCARGAYYTNCAR ACNAARGTNYTNGARTGYTAYCARACNAARCCNGAYTCNATHYTNCAYTGYTCNCCNGTN GTNAAYGCNTTYTCNACNTGYGTNGARMGNGCNMGNYTNACNGTNTCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GTNMGNAAR GGNAAYCARGTNMGNTAYYTNAARGTNMGNMGNTCNGGNACNYTNMGNMGNTTYCARAAR GTNGCNYTNGGNYTNGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GTNTCNMGNTTY MGNGARTCNACNGAYYTNGGNCARYTNYTNGAYCAYCCNGAYCCNMGNTGGATGTCNATG AAYGTNYTNGGNCARGTNGTNAAYGTNYTNMGNGARTGYAAYATGCCNTCNGTNCCNGGN TAYMGNYTNCARGTNACNTCNCAYGTNYTNATHCCNGCNATHTAYGARGCNGGNATHACN YTNTTYATGMGNAARGAYAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------MGNCAYATHGTNATHGAYGGN AGYAAYGTNGCNATGAGYCAYGGNYTNAAYGTNTTYTCNTGYYTNGGNATHAARATHGTN GTNGAYTGGTTYAARAARMGNGGNCAYAARAAYATHACNGTNTTYGTNCCNCARTGGMGN AARGARGCNTCNMGNCCNGAYGCNCCNATHTCNAAYCARGARATHYTNAAYGARYTNGAR CARGARMGNATHGTNGTNTTYACNCCNGCNMGNMGNGTNGGNGGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNGCNGAYCARATGTTYGAY MGNGTNMGNCARAARATGAAYAARACNTCNTCNTCNCARTAYACNGTNAARGTNTCNCCN YTNGARATGTCNGAYYTNGCNCARCCNTCNTTYYTNCARATHATHCARYTNCAYCCNTCN ACNACNGTNTTYTTYCARCAYCARGCNGTNAARTTYMGNAARAARAARGGNTTYGCNGAR GCNACNTTYTAYACNATGACNGARYTNAARGARTTYGTNTAYCARYTNACNCARYTNAAR YTNTGYGARAARMGNATHGAYGTNGTNATHACNGCNYTNMGNCCNAAYCARAAYCCNGAY GTNYTNTCNTTYGTNYTNCAYYTNAAYMGNAAYGGNAARYTNYTNAARYTNATHGAYAGY GGNGARGAYCCNAARATHAAYAARCCNATHCCNGTNGGNYTNGAYACNCCNAARATGGAR TTYGARTGYGTNCCNTCNTCNAGYAAYGGNGCNTAYATGCAYAGYATGTTYCCNTTYACN AAYAAYGTNYTNATHAARMGNTCNCARGTNGGNAARGARACNAAYCCNGTNTAYCAYGGN CCNYTNTCNGTNTTYTAYGTNAAYGARAARTGGATGGARGCNGTNGCNGARTGYTGYACN GAYTTYAARATHAAYAAYTAYCCNYTN------ACNCCNGTNGGNAAY------------ ---------------------------------------AARACNGAYAARAARCCNGTN GARTCNGCNACNGGNCARAARCARAGYGAYGAYGARMGNATG---GARTTYGARGAYGAY GAYCCNGTNTCNAAYATGACNMGNGAYGTNTGYGCNGAYATGYTNGARTCNATHAARAAR YTNAARGARYTNGARTCNGAYAAYCCNAAYATGGARAARATHYTNGARATGCARGCNCAR YTNAAYGARYTNCARAARTCNYTNATHAARCCNGGNAARACNTCNMGNAGYAARGAYAAR GARGAYGAYMGNAGYACNGAYCCN------------------------------------ ------------YTNGCNTCNGGNGARAARAARCARCARAARATGGGNAGYYTNGARGAR TTYGTNGARGARGCNGAYMGNTCNGARMGNCARMGNGARGARCARATGAARCARCARMGN GARGAYGARYTNCARAARAARMGNGAYTCNGARYTNMGNMGNAARTCNCARTGGGCNAAR AARGTNATHTCNGAYTAYAARCARGARGGN------GTNAARGGNGARATHAGY------ ---GARGARGCNGARMGNATGYTNMGNCARMGNGARCARMGNATHAAR------------ ---GARAARGARGARGARGARAARMGNAARGARCARGARMGNCARMGNMGNYTNMGNGAR AARGARGARGARGARMGNAARGARGCNGCNMGNYTNAARGAYTCNCARAARGCNGAYAAR GCNTCNGCNTCNMGNYTNYTNTGGAAYACNTCNGGNCAYGAYACNTCNACNAAYMGNCAY MGN---TCNGCNGAYTCNACNAGYGGNAARMGNGAYMGNGAYMGNGAYCARMGN------ ------------TCNAARMGNGARAAYGTNMGNCCNMGNGARGARGARMGNCAYTTYACN CCNGARGARGARCCNGARTAYACNGTNGTNATGGARAAYGAYTAYCARGAYYTNTGGGCN MGNAAYCAYACNYTNCCNGTNAAYTAYMGNGTNMGNYTNACNAGYGTNGTNAAYMGNTTY TGYCCNATHCARGGNTGYCCNGCNAARACNTGYTTYMGNGAYGARGARTCNTAYCARGAR CAYTGGTCNATHTTYCAYGARCCNCAYACNACNATGMGNTTYTGYCARAARTGYTCNGCN TAYTTYATGAAYTAYGAYGARYTNGARAARCAYATGATHAARMGNCAYCAYTTYAAYTCN TTY---GARGCNAARMGNYTNGCNMGNAGYTCNMGNATHAARGTNGTNGGNAAYCCNAGY TTYMGNGAYCCNYTNCCNTTY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNYTNTCNGCNGTNTAYAAR YTNGAYCARCAYGARAARGCNMGNAARGARGCNGGNGARTGYYTNGTNTCNYTNMGNGGN GTNGARGCNMGNGTNGTNGAYMGNYTNAARGCNTAYAARACNAARAGYGTNACNGARMGN ATGMGNAGYGTNGAYTAYAGYACNYTNMGNGARGCNGGNATHGCNTGYCARCARATGMGN ACNTGYYTNAAYGARATHTGYACNATHATHTCNYTNGCNTGGATHACNGARYTNCCNCCN GTNAAYGAYCARGGNTGYTTYTAYATHCCNGARTCNGARCARGARAAYGARAARYTNAAR TTYGARYTNAAYGARYTNCARTCN------------------------------------ ------------------------------------------------------------ ---GTNATGAAYAARGGNAARCARACNMGNAGYYTNTCNGCNTCNTTYGAYGAYGARMGN GAYYTNACNGARTCN---------------GAYGAYMGNGTNACNACNATGGAY------ ------MGNGARYTNGARATHGARMGNAAYTCNACNGAYGAYTGYAGYAARATGYTNAAY CCNGARTTYMGNGGNCARTAYGARCARATHAARAARTCNTAYGCNGAYYTNYTNTAYAAR TGGGGNYTNYTNAAYCARMGNACNCARGTNYTNAARCAYACNYTNTCN---GCNCARGGN GAYAARAARATHGARTTYTCNATHCCNTGYTCNAAYTGYTGYGAYGTNGTNYTNAAYGTN CARTGYAAYAARTGYCAYTAYCCNTCNYTNAAYTGYTCNATHTGYCAYGTNGGNGTNMGN GGNCCNGCNAAYATGTGYYTNGCNTGYGGNCAYGGNGGNCAYTCNAGYCAYATGATGAAR TGGTTYCAYACNAAYGTNYTNTGYCCNTCNGGNTGYGGNTGYAAYTGYYTNCARGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AARATHAARGCNGCNGTNYTN GAYTGG------ACNYTNGAYATGGAYATHAAYGCNTGGGGNCAYTTYGAYYTNGTNATH GGNGCNGAYATHATHTAYATHGARGAYACNTTYACNTAYYTNYTNAARACNYTNAARTTY GTNGCNCCNTCNTCNAARACNCARGTNYTNYTNTCNTGYMGNATHMGNTAYGAYMGNGAY YTNAARTTY--------------------------------------------------- ---------------------------------------YTNGTNACNCAYTTYGGNGGN TGYCAYTGYGGNGCNGTNMGNTTYTCNGTNCARGCNCCNGCNCAYATHGAYGTNGTNCAR TGYAAYTGYAGYATHTGYACNAARAARCARAAYCAYCAYTTYATHATHCCNAARTCNMGN TTYAARYTNATHCARGGNGARGAYTCNYTNACNACNTAYACNTTYAAYACNAAYAARGCN AARCAYACNTTYTGYAARGTNTGYGGNGTNCARAGYTTYTAYAGYCCNMGNTCNAAYCCN GAYGGNTAYGGNATHATGCCNCAYTGYATHGAYCCNGGNTCNATHCARTCNACNAARATH ATHACNTTYGAYGGNAAYCARTGGGARAARGCNTTYGARAARTCNGAYATHACNGARTAY TCNAAR---------------------------------------------------AAY CAYATHGCNATGGARACNGGNCCNAAYGGNTCNTGYAARTTYGTNGGNTGYGGNGARACN GTNGAYAARTAYCCNYTNGTNGTNGGNACNGARTAYAAYTGYCCNTTYYTNATGAARYTN GARAAYAARGGNCAYATHATHMGNGGNGARYTNTAYGARGTNGAYACNGARATGYTNGCN TAYYTNGAYAARYTNGARAARCAYCCNAARGTNTAYMGNMGNCARCARATHGAYGTNMGN YTNACNGARGAYAARGAYGAYCAYCCNYTNTCNCCNACNCCNGTNTAYAARAGYTGGGTN TAYTTYTTYCAYGAYGTNMGNGARGAYATGATHCARYTNAARTGGATHTCNGAYTAYCAY TCNAARTCNGTNGAYAAYCCNGARTAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNAARTCNGTNTGYGTN GARATHTCNCCNAAYGCNTGYGAYYTNACNGARTTYAAYGCNAARAARGTNGGNGTNGAR GAYMGNYTNAARATHATHAAYGARGAYTTYACNAAYTGYAARGTNYTNGCNCARYTNAAR TCNYTNGGNCCNTTYTCNYTNTTYGTNAGYAAYCCNCCNTAYGTNACNACNAARGARATG AAYTGYYTNCCNCCNGARATHGCNMGNTTYGARGAYCCNGTNGCNYTNGAYGGNGGNYTN GAYGGNYTNGAYYTNGTNMGNTAYATHYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGGARTCNGCNMGNYTN GTNGCNAARYTNCCNACNAAYTTYTCNACNAARCAYAAY---CAYCCNGTNTAYATGGAR CCNAARGCNCCNTCNCCNCARCCNCCNAAYMGNCCNYTNTCNGCNMGNGTNCCNMGNCCN GGNTCNGCNMGNCCNGARTCNTCNAGYTCNCAYCAYMGNGCNCARTCNGCNATGCCNATG MGNGGNGARGARACNATGACNGCNCCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNTCNMGNCAYGGNATHAARGTNYTNGAYATHGCNGGNAARGARGTNYTNCARMGNCAY CCNYTNCAYACNATHGCNCARYTNACNGARTAYAAYGAYGGNTTYGGNMGNCARAAYATH GCNGTNAARATHGGNCARGTNGGNAARAAYGTNTAYCARTGYTAYGTNTTYCARTGYCAY TCNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNGAYTCNCARACNATHGARMGNMGNCARAARAAYATHTCNTTYGGNAARTCNACN GCNTCNTAYCARMGNTAYATHGCNGTNGTNCCNAARGAYAARMGNGAYTCNATGAGYGGN YTNCAYCCNACNACNCCNGAYATHTGGCARATGTGYAGYMGNMGNAGYTGGGAYCARCAR ATHAARAAYTGGAARAARTCNYTNCAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARGARGTN---GTNGAR GTNGGNAARGGNAGYGTNTGYTTYTCNTTYCAYAARACNACNAGYAARATHGCNACNACN TCNGCNTTYAAYCARGARGARTCNGAYCCNATHGARGTNCCNCCNTCNMGNCCNYTNACN YTNYTNGAYAGYATHGARGARGARAARAARYTNATGACNYTNGGNYTNGTNGAR------ ------GGNTCNGARGTNACNCCNTCNTCNAGY--------------------------- ------GARGAYGTNGAYACNAARCAYTCNAARCCNMGNYTNYTNGARGAYTTYGTNCAR GTNAAYYTNATGAARGARGGNGGNGGNGARATHCCNTGGCCNGCNGARACNATHAARTAY ACNTCNACNCARCCNTCNATHCAYTAYGCNTGYAAYCCNATGCARTTYGAYTTYAARGAY ATGYTNAARGCNGCNGGNGGNGGNGGNTCNGTNGCNACNGGNGAYGCNAARGAYGCNAAR AAY---------GARGCNGARAARAARGARGGNAGYAARGARGAY---------AARGAR AARAARAARCAY---TCNMGNAARAARMGNAARMGNAARAARAGYAAYAARGAYGAYGGN ACNGAYAARAAYGCNGGNAARGARGGNGARGARAARAAYCCNGARGGN------AARGAR GGNGARGARGAYAARAARGARAARAARAARAARMGNAARAARAARAARAARAGYAGYAAR CAYMGNCAYAARGGNAARAARGARGGNGARGARGCNGGNGGNGAYYTNACNAARGGNAAY AARGARGARGGNGTNGARAARGGNGAYGAYGTNAAYAARTCNMGNMGNMGNTCNCAYMGN AARMGNACNCAYACNGCNGARGARAARGAYAARCCNGGNGARGARAARGTNGGNGARAAY GARGTNATGGTNAAYGGNAARAARMGNTCNTCNCAYAARCAYGCNGGNAGYAARCAY--- ---AARMGNAARMGNAARCAYMGNMGNMGNMGNCCNGARMGNTCNGARAARGCNAARGCN YTNAGYGCNTCNGARAARGCNAARGTNGARAARAAYGTNGAYACNGTNAAYGCNAARGAR CCNAARGTNAARATHGAYTAYGAYGAYGARGARGARACNCAYATHCCNACNGAYAARGAR GAYGARGCNGTN---GARCCNAARATHAARMGNCCNTGYMGNTCNMGNAARMGNCAYMGN MGNAAYAGYAAYCAYAARGAYACNGGNGAYGARAGYACNATHAARACNGARGAYCARTGY TCNGAYGARYTNAAYATHACNTTYAARACNCAYAARAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GGNATH GGNATHAARACNTTYYTNCARYTNATHAARGARYTNAARMGNAAYAAYGCNGAYGAYATH YTNGAYTGGATGMGNTCNYTNMGNACNAAYCARCARYTNAGYTCNYTNAARGARACNGTN GARACNAARAAYGGNATGAARMGNGARACNCAYTGYTCNMGNTGYTCNCAYYTNGGNTCN GTNAGYAARCAYAAYAARAAYGGNTGYGTNATHTGYTCNACNCAYGARGGNTGYAARGAR GARAAYAGY---------------------------ATHTCNTGYTCNTGYCARTTYCAY GTNTTYGARGARMGNGTNGAYCCNTTYYTNATHCARYTNAARGTNCAYGGNGCNGCNYTN AARATGTCNAAYTTYCCNAAYGARGARGTNATHGCNGARTTYYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGGAY ACNGCNGARATHTCNMGNYTNMGNGARGARCARCARAARGCNATHGCNGARACNGCNGAR AARATHATGCARTTYGARAARTAYAARTCNGAYTAYCARACNYTNCARAARMGNYTNAAR ACNYTNCCNGAYAARYTNTCNCAYGAYGTNATGGTNCCNTTYGGNAARYTNGCNTTYATG CCNGGNCARATHGTNCAYACNAAYGARGTNYTNGTNYTNYTNGGNGAYAAYTGGTTYGCN GARMGNTCNGCNAARCARGCNCAYGAYATHGCNAGYMGNMGNATHAARGARYTNGAYAAR MGNATHGARGAYYTNAARGARCARCARAGYYTNYTNGARCCNMGNYTNCARATHACNTCN GARYTNCARGCNCARGCNAARGGNACNGGNGGNTAYCAYGARATHGTNGARGARTAYGAY GARGARAARGARMGNYTNTGGGAYGARCARCAYAARGARAAYGTNMGNMGNCAYCAYGAR AARAARMGNYTNMGNAAYGCNCCNAARAAYAARACNCCNACNACNCAR---------GGN AAYGTNATHAGYGAYGARGARYTNTGGTCNMGNYTNGAYGCNYTNGARATHCARGARGAR GARMGNMGNGARYTNAAYAGYTCNGAYTCNGAYACNTCNGAYGGNGARGAYMGNYTNAGY ACNATHGAYGTNGAYGARGAYATHGAYATGAARMGNGTNAGYTGGGTNGAY--------- ---------------------------------------GARGARGARGCNACNCAYGGN GGNGTNGAYGARGAYTCNGAYAAYGAYGAYGARGAR------------GARGAYGARGAY GARGARGGNAARAAYAARCCNGTNGTNAARACNATHTTYTTYAGYCAYTCNGCNACNCCN GCNGCNAARYTNTTYCCNAARCCNGARGCNCCNAGYATHAAYAGYCCNTCNGAYATHTAY AARYTNTTYTCNCCNAARCCNATHYTNAARAARACN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNTTYCAYTCNGGNAAR ACNAARGCNTCNACNGTNGAYAARATHATHAARATHGTNGARGAYGARGAYMGNYTNGTN MGNGARAGYGCNTGYYTNAGYYTNGGNTAYYTNMGNTCNTCNAARGCNGTNTCNTAYGTN GTNGAYMGNTGGMGNAAYGAYCCNATHTCNACNGTNMGNGARGCNGCNGARYTNGCNYTN AGYMGNATGGAYGCNCCNGAYGCNGTNCARTGYATGAARGTNACNAARGTNYTNTCNTCN GARATGAAYGCNYTNAARCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYACNAARGAYACNAAYAARATGGAYACNTGYGTNCCNAAYCCNAGY YTNATHAAYACNCCNTGGGCNACNAGYCCNCAYTCNTTYTCNATHTAYGAYCARGARMGN CCNAGY------------------AAYGTNTTYTGYGGNGGNTCNAARYTNCCNACNYTN GAYATHGGNYTNACNGARGARGGNGGNYTNGAYGAYAAYATHGARGAYAGYTCNYTNAAR AGYATHYTNACNCCNGARYTNATHAAYTCNATGTCNTCNTCNTCNGGNYTNAAYACNTCN TCNTTYCARTGGGGN---------------ATHAARAGYAAYCARGARGARACN------ ------CCNACNCCNACNTTYGCNCARYTNGGNATGGAYTCNGAYYTN---YTNATHCCN GAYTTYTTYAAYATHGAYTCNAAYGAYAGYAARTTYTCNTTYCCNACNTTYGAYYTNGAY TCNATGACNAGYAAYCCNCCNTCN------------------------TCNTGYCAYACN CCNGTNCCNTCNGARTCNAARACNGAYTAYCCNGARACNTCNTTYGAYMGNMGNATH--- ------------TCNATGCCNCARAGYAARGARAARGAYATHATHGGNGCNGAYTTYYTN CARAARAARTTYCCNATGAARACNAAYTTYCCNCCNMGNACNACNCARCCNCCNGTNGGN GTNGTNACNCCNGTNAARATHCCNGARGAY------------------------------ AAYTCNATHTTYAAYAAYCAYGCNGCNCAYGTNGARATGAARYTNAARAARGAYACNGCN AAYATH------------------------------------------------GCNYTN GAYGTNGCNGAYYTNGCNCCNCARATGGTNCCN------------TCNTAYMGNGARGAR TCNACNGAYGTNGTNAARYTNGARCCNGGNTCNCCNGAR---YTNATHAARAARMGNGAR TCNAARMGNTCNTTYGARGAYACNTGGGARGAYGTNAAYCAYYTNATHTCNAGYGAYYTN GCNGCNGCNACNAARAARMGNMGNMGNTGYGAYTCNGGNAGYTCNGGNCAYACNTCNGAR GAY---GTNGAYGARGAYGARAAYGAYTTYATGTAYAAYATGGAYGAYGAYAGYGAYGAY ---------GAYYTNGAYGAYGAYYTNGCNTAYATGAARCCNGGNGGNTGYGARTCNYTN ATHGAYGTNGGNAARAARCARAARCARTAYTTYTGGCARTAYAAYGTNCARGCNAARGGN CCNAARGGNACNMGNYTNAARYTNGCNGTNGARGCNCCNTCNGAYCCNCAYGTNYTNAAY GGNTTYGARGAYCCNGTNTTYGAYGARGGNAAYACNCARGTNGCNGGNATHMGNCAYGGN GGNAARGCNMGNAARGGNGAYGGNAAYGARGTNACNCCNAAYCCNCAYAARYTNTTYAAR ATHGGNCAYCARYTNYTNMGNYTNAAYAARGARATHAAYGCNTGYCARYTNGGNTCNGAY GTNCCNYTNGCNAARMGNAAYGARTCNMGNAARGARAARAAYAARYTNGCNTCNMGNGCN TGYMGNYTNAARAARAARGCNCARCAYGARGCNAAYAARATHAARYTNCAYGGNYTNGAR ATGGARCAYGGNCARATHAAYAAYGTNYTNMGNYTNATHYTNCCNAARYTNMGNGARMGN GCNAARGARYTNCARAARAAYCARCAYGCNACNGARAARGTNGARAARCCNGAYCCNGAR AAYAGYYTNACNAAYATGYTNACNGGNYTNATHGCNTCNAAYYTNAARACNATGGTNGCN AAYCAYACNACNGAYTAYGTNAAYAAYGTNATHYTNACNGTNGARMGNGGNGAYYTNMGN GGNGGNYTNAAY---YTNMGNACNMGNAARACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARGAYYTNAARAARATGAARGTNCCNGARYTNAARCARGCN YTNAARGARAARGGNYTNTCNACNTCNGGNACNAARCCNGARYTNATHAARMGNYTNGTN GARGCN------GGNTCNCCNGTNACNAGYAGYGAYCCNGTNYTNGAYGAR--------- ------GAYGARATHYTNAARGAYGAYCCNGCNCCNTCN--------------------- GCNGCNCCNGTNCCNTCNAARCCNTCNTCNACNGTNAARTCNGAYAGYCARGCNAAYGGN GARACNAARAARCCNGARACNAAYGCN------------------------AAYATH--- ------CARATGCCNGCNGAYACNACNGTNGCNAARCCNACNGARATGTCNAARYTNTCN GAYGCNGARMGNYTNAARYTNMGNGCNGAYAARTTYGGNATHTCNTCNGARCARGCNAAR AARGAYYTNMGNGCNCARMGNTTYGGNATHTCNCCNAAYGARAAYAARTCNGGNAGYATH AGYACNTCNGGNACNTCNGTNGAYGTNGARAARYTNAARAARMGNGCNGARMGNTTYGGN GTN------------TCNACNAGYTCNGTNTCNCARGAYGARYTNAARMGNAARMGNGCN GARMGNTTYGGNACNACNYTNAAYGCNTCNTCN---------AAYGTNAAYGTNAAYTCN ACNGAYAGYGARYTNGARGCNAARAARAARAARMGNGCNGARMGNTTYGGNYTNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AAYGCNTAYCCNTCNCCNYTNTCNYTNYTNTCNAARATGTTYATGACNGARATGGAYAAR GCNTCNGARGARMGNGARTAYACNYTNGAYTAYTTYYTNCAYYTNYTNGTNTAYATHTAY TCNYTNTCNGAYGGNAGYAGYGARAAYCARGAYGARATHAARYTNYTNCARGAYCARYTN ATHCARGCNGTNATHAARAAYAARAAYAAYYTNTCNCCNATHATGCARTAYACNGTNGGN GARAARGTNTCNGARACNATHYTNTCNGAYCARATGGARACNYTNTGGGAYAARYTNGAY TCNATGATGGARGCNMGNMGNGAYYTNAARGARTTYGGNTGYYTNGTNGAYCCNGGNGGN GCNATGAGYCCNGCNGCNATHAARCCNYTNYTNMGNCARGTNATHGAYMGNATHGTNGAY CCNGCNAARCCNGARYTNCCNGAYATHGARTGYAARTCNGGNGGNYTNAARGAYYTNYTN AARTCNGGNTTYGGNTTYTTYAARAGYTCNGCNAARCCNMGNCCNGGNGAYGCNCCNYTN YTNATGATHTTYGTNGTNGGNGGNGTNACNGCNTCNGARGTNMGNCAYATHAARGARGCN GTNAGYAGYTCNAARCCNGAYTTYGARGTNGTNGTNGGNGGNACNMGNYTNAGYAGYATH GARTCNACNYTNACNTCNYTNYTNGTNAARGAYAAYATHAAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNTTYYTNACNACNTTYCARCARCCNAGYCCNAAY YTNGTNATGGGNCAYCARCCNTGGAARTGGYTNTTYGTNTCNATGGARTGYMGNAARYTN GTNAARGARAARCAYTTYGCNTCNGCNYTNCARAARYTNCAYGCNTCNGTNAARGAYTGY CARGARCCNACNAAYAARTGYMGNYTNYTNTGYYTNTTYGCNGARTGYTAYTTYCAYATG GGNTGYCCNCARYTNGCNATHCARACNTAYMGNGAYGCNYTNMGNGTNGAYAGYTCNTGY GTNTCNGTNYTNTAYCAYYTNTCNYTNATHTAYCARAGYYTNAAYYTNCCNGAYCARGAR YTNGARTCNYTNAAYYTNTTYGTNATGGCNYTNGCN------GARGAYAARAARMGNAAR GARACNATHCCNGTNATHGAYYTNGAYGARYTNATHTGGTCNGTNCAYCCNCCNACNCCN GTNGTNTCNTTYYTNGGNGCNAARGTNACNTTYGCNAARMGNTGYYTNCARYTNCARMGN TTYCAYGARGCNGCNGARCARTAYTCNAGYYTNATHCARATGTTYCARGAYGTNYTN--- ------GARTTYGARAAYMGNGCNAAYATHCARCARATHAAYATHGCNGARATHYTNGTN GAYGCNGCNGARGTNYTNYTNATHACNCARCARTTYCARGAYTGYYTNAARATHTGYGAY CARACNYTNCCNTCNYTNYTNGCNCAYAAYACNCARACNYTNGAYAAYTCNTCNYTNGGN AGYTTYGAYAARTCNCAR------------------------------------------ ---------------ACNGAYTTYTTYAGYGAYYTNGCNATGTCNCARACNGAYGAYGAY GARCCNATHGAYYTNTCNTCNACNCCNAARAARAAYACNAARGCNACNMGNAARGGNGAR TCNYTNGTNGAYYTNCAYGTNTCNYTNGAR------------------MGNTCNMGNAAR MGNYTNMGNTCNAAYAAYGGNGARCAYTGYAGYGAYGAYGCNGAYAGYGTNGAR------ ---------------GAYATHYTNATGACNMGNYTNYTNYTNTGYAARGCNGAYGCNYTN ATHYTNTCNGCNGGNTTYACNGAYCARGCNGTNAAYTGYYTNCARCARGCNYTNGAYATH YTNYTNTGYTAYCCNACNCCNACNGTNGTNGAYGARTCNGGNGCNGAYACNCCNCAYGCN AARMGNCARMGNATH---------------AAYTCNGAYGGNAARGCNTCNGGNCCNCCN ATGTCNGAYGGNGGNCAYTCNAAYTCNTCNTGGTCNAARYTNYTNATHGAYACNGCNYTN MGNATGGCNMGNGCNTCNTGGGARMGNAGYMGNTTYCCNTCNGTNYTNAAYAGYTGYMGN YTNYTNGARCARATHGAYAARGAYAAYYTNAAYGCNYTNTAY------------------ ---------------TAYCCNCAY---CARAAYTGYATGAARTTYGAYGTNTGYGAYCAY GGNACNMGNGTNACNATGAAYTGYCCNGTNCARYTNGTNTTYAAYTCNGARAARCARGTN TGYGAYTAYGTNCARAAYGTNCCNMGNTGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNYTNAAYYTNGAYMGN YTNGCNTGYTAYYTNTTYGGNATHGAYAAYCCNMGNYTNYTNTAYTCNGARAGYGARAAR TTYATHAGYCARTTYCAYAGYGAYYTNTCNATHTGYCARTAYMGNCCNTTYAAYYTNTAY CCNATGAARTTYGTNCAYGAYYTNAGYTTYTGGGARAARGAYGTNGAYTCNGAYCARTTY GAYGTNTTYAGYYTNTAYGARACNATHMGNAAYATHGCNGGNGAYGTNGTNGTNAGYGTN AAYYTNATHGAYATHTAYGARGAYCCNGAYTCNAARMGNMGNAGYMGNTGYTAYMGNYTN TAYTTYCARTCNTTYGAYAARTGYYTNTCNTAYGTNATGTCNTGGAARYTNCARAGYAAR ATHMGNATGGARGCNGCNMGNAGYYTNGGNGTNCARYTNMGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNGCNGAY YTNGGNCARCARGAYMGNGTNYTNGTNGAYCCNTTYGTNACNAGYACNCCNCCNCCNTCN AARMGNAARAARMGNGAYACNGARTCNTCNGAYGARGGNGTNGGNTCNYTNTCNGAYGCN TCNGAYGAYGGNGGNGTNGAYYTNMGNCARAARCAYGARGCNYTNAARCAYCARATGGAR MGNGARAARCARMGNGGNGAYTCNYTNGARGARGARAAYMGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGAYAAYCAYGAR GARATHYTNGAYGCNYTNACNGCNTTYGGNAARAGYCCNAAYYTNCARGARATHCCNTCN GTNYTNGARCARTAYYTNAAYTGYGTNGCNAARAAYGGNGARACNYTNTTYCCNTGGTCN CARYTNAARCCNYTNATHYTNMGNAARATGGARYTNGTNATHATGGARYTNMGNMGNAGY YTNGCNTCNGARAAYATHCCNAAYMGNCCNAAYGTNGARAAYGTNMGNTTYGAYGTNATG CAYGCNMGNATHATHGAYTCNYTNCAYAARTTYAAYGGNGCNCCNTTYACNATHCARMGN YTNTGYGARYTNYTNATHGAYCCNAARMGNCAYTAYAARMGNAGYGAYAARTTYATGMGN GGNYTNGARAARAAYGTNYTNGTNGTNAGYACNGTNGAYCCNTTYGGNMGNAARGTNGTN TGYGARTCNGGNAAYAARCCNATGYTNAAYGGNATHYTN---GAYATHAAYGGNTCN--- TAYCCNCCNMGNGAYTCNGCNATGAGYGTNCCNYTNCCNCCNGTNCCNGGNTGGGTNACN ACNTCNTCNGGNTCNTCNGCNACNTCNMGNACNGCNGCNACNGTNACNCCNCCNGAYTCN AARGTNGGNACNAGYGARAAYMGNAAYAARGAYTCNGAYGTNGTNTCNAAYGGNATGTCN GGNGGNATGACNGTNTCNAGYTCNGTNTTYACNGAYCAR---GAYGAYCCNYTNGCNGTN CARTCNGARGARGTNGTNGARGARACNGTNGTNACNATGGAYACNGGNGARGTNAGYTCN GTNGTNACNGAYGGNGGNGARGCNATGGCNGARGARGCNATGGARGGNGAR------ATG GCNGAYGAYMGNGAYGCNTCNTCNTTYTCNTCNTCNTCNTCNTCNTCNTCNGARGARYTN TCN---------ACNTCNTCNGAYTCNATHTCNCCNTTYGGNGTNGTNATHAAYAGYTTY AAYGAYGARGCNGCNGARAAYMGNCCNTGGGCNGCNTTYGCNCARGAYGTNAAR------ ------TGYCAYGARGAYGTNACNTCNCAYCCNTCNAAYAGYGARCCNGTNAARAAYATH TCNGARGARAAYCARACNCCNCARGCNTCNTCNTCNTCNCCNTCNACNAGYATHGARACN TCNTCNTCNYTNYTNTCNTCNTCNYTNGARACNCARTCNTCNYTNYTNTCNACNACNACN TCNTCNAARGGNGARGAYAAYATHGARAGYCARGAYTTYYTNAAYCARTCN--------- ---------------------------GCNTCNGARCARACNTCNTGGYTNTCNACNGAY AAYTCNTCNACNGCNAAY------GARAGYTTYGGNTTYGARCCNGTNCARTCNGCNTCN GAYCAYGTN---------------------YTNTCNYTNCCNGARGARACNYTNAAYTCN GTNTCNGAR--------------------------------------------------- ---CARGCNTCNTCNACNACNACNACNGTNACNACNACNGCNAAYAAYCCNACNCCNGAY CCNACNAAYACNGTNTCNCCNTCN------------------YTNTCNCCNTCNTCNTCN CARAGYGTNCCNACNTAYGCNCARGTNGTNGCNTCNTCNACNGAYATHCAYYTNACNCCN TAYGAYTCNTCN---------------------GAYACNGTNCCNTGYGAYAGYGTNGCN GGNYTNGARMGNYTNGTNGGNTCNATGGARCARTCNYTNTCNTCNTCNCCNTCNTCNTCN GCNCCNATHGCNCAYATHTCNTCNTCNTCNTCNTCNCAYCCNGAYYTNTCNCCNAGYATH AAYTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CARATHGCNGTNCCNATHTCNATGATHAAYGCNAAYGCNAAYYTNYTNCAR GCNCARCCNGGNGTNYTNGCNAAYTCNACNTCNACNAGY------TCNACNGCNACNYTN GTNACNATGGTNACNGCNYTNCCNGCNTCNTCNACNAAYACNACNACNACNACNACNATG ACNGGNTCNTCNCARGTNGCNGTNTCNACNGGNTCNAAYATGYTNTCNTTYCCNGTNGGN YTNAGYGGNYTNACNCARYTNATGCCNGTNACNTCNAARGGNCARGCNGGNCARGCNATH MGNCCNACNGCNATGCCNYTNYTNCARYTNCARGGNCARCARGGNATHCARYTNYTNAGY YTNCARCARMGNGGNCARGTNAARCARGGNACNAGYAGYTCNAAYACNGCNCARGGNATH ACNMGNYTNGCNCARGCNGGNACNACNACNGTNCCNYTNTCNACNGTNYTNGCNGGNCAR CARATGACNGCNYTNGGNATGGGNAAYAARGCNGGNCARGGNGGNGGNACNGCNATHACN GCNCARCARYTNATHCARYTNACNGGNGGNCARGGNGCNTCNYTNGGNCARGCNAAYGCN CARMGNGCNGCNCAYATHACNYTNGGNAARGGNCARCARGGNYTNCARTTYCAYTCNYTN CARYTNAARCARGGNGGNGCNACNYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ACNAAYATGTCNGCNAAYACNAARGTNAGYATHTCN AGYGARAAYAAYGTNGGNGAYYTNCCNGTNYTNGTNAGYGGNGAYCCNACNAARYTNGAR MGNGGNYTNATHGTNYTNCARGARTGGTGGGGNATGAAYGARCARATHCARGAYTGYGGN AARGAYYTNTGYAGYMGNGGNAAR---ATGGTNACNATHGTNCCNGAYYTNTAYMGNGGN AARGTNACNACNGAYAAYGARGARGCNGGNCAYTTYATGGGNAAYYTNGAYTGGCARGGN GCNGTNAARGAYATHCARGCNTGYGCNAARTAYYTNAARTCNAARGGNGTNAARAARGTN GCNGTNACNGGNTTYTGYATGGGNGGNGCNYTNTCNATGGCNGGNGCNGCNYTNGTNCCN GARATHGAYGCNGCNGTNCCNTTYTAYGGNATHCCNTCNCCNGARYTNTGYGAYGTNACN ACNATHAARGTNCCNYTNCARTGYCAYTTYGCNGARCAYGAYCARACNGTNGGNTTYGCN TCNCCNGCNGARTGGAARCCNYTNAARTCNAARYTNGARGGNAARYTNAARGAYYTNGAR TTYTAYGARTAYGAYGCNGGNCAYGCNTTYACNAAYAARAARGGNGAYAAYTAYAAYGAR AARYTNTGYGARCARGCNTTYAGYMGNATGTTYGGNTTYYTNAAYAARCAYYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TAYACNACNGGNYTNGGNATHYTNGARCCNATHMGNGGNGGNGGNCCNAAYCCN GCNGARAARCAYCARCCNTCNATHCARCCNACNYTNYTNGAYACNAGYAARCCNGARGAR ACN------AAYAARGTNYTNGAYATHCCNCCNGTNGAYTTYGAYTGGGGNTCNAGYGGN YTNACNAAYCCNYTNAARGTNTTYAARAAYGARAGYTTYAAYACNGGNYTNTCNTCNYTN GARCCNTTYTCNGAYGTNYTNCARAARAAYGCNGAYCCNCCNAARGARYTNAGYAAYGAR GCNAARAGYATHYTNTCNAARATHCCNAAYYTNAAYTTYATGMGNTCNAAYGTNYTNATG TTYCCNATHAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AAYAARGAYCAYATHYTNGARCAYYTNCARCAYGTNATHTCNACNAARCCNAAR GAYCARYTNTCNGAYGARGARYTNGARTTYCAYTAYTTYAARYTNCAYGAYTAYGAYAAY AAYAAYAARYTNGAYGGNGTNGARATHGGNAARGCNYTNACNCAYTAY------------ ------------------GAYGCNGTNGCNTCNGAYGCNCARAARGCNTAYGTNTAYACN GAYATHGARYTNGGNAAYGCNATHGAYGARGCNYTNAAYGAY---GAYYTNAAYGAYGAY GGNTAYGTN--------------------------------------------------- ------------------------------ATGGGNMGNCAYMGNTCNAGYGAYTCNGAY GGNGAYTAYTCNMGNTCNAARAARAARGARAARAARAARGCNMGNTCNMGNACNMGNTCN AAYAGYTCNAGYGAYTCNAGYMGNMGNTCNAGYACNMGNCAYAARAARTCNAARAARAAR CAY------TCNAGYMGNAARGCNTCNCCNAGYCCNGAYMGNCARAGYCAYTAYMGNGAR MGNTCNMGNMGNTCNMGNTCNCCNTCNTCNGAYMGNMGNGCNCCNMGNMGNTCNMGNTCN ---------------CCNGARGTNTCNMGNMGNMGNTCNMGNTCNCCNTCNMGNMGNMGN TCNMGNTCNCCNTCNTAYACNMGNGAYMGNMGNTCNMGNTCNGGNTCNMGNGGNTAYMGN TCNAARGGNCAYCARMGNMGNTCNMGNTCNAGYTCNMGNGGNCAYGAYMGNTCNMGNTCN GCNTCNMGNCAYMGNCAYGAYAAYTCNTCNAGYMGNTAYGGNAGY--------------- ------------------CARGARMGNCAYAGYTGYGAYCARACNCAYACNATGACNTCN CARGARYTNGCNGARATHMGNATGMGNAARGCNYTNCARGCNGCNGCNATHGCNGAYMGN AARYTNAARGGNYTNGARGGNCAYGGNTCNCCNTCNAAYGGNTCNAGYAAYGGNCARGGN CARGGNTCNMGNTCNCCNCAYATHCAYATGTCNTCNMGNAARTTYGCNGAYTCNGTNGCN TCNATHGARTCNGAYAGYTTYGTNCARTCNACNTTYAARTCNTCNMGNAGYAAYGTNAAR GARGAR---CCNYTNGAYCCNYTNATGTCNAGYCAYGAYGAYGCNATHTTYGGNTCNYTN TCNTCNATHGGNTTYACNATHAARCCNGAYYTNGAYAGYAARCCNGTNTCNATGGAYCCN GAYTCNATHATGCAYCCNAGYYTNTTYTGYAAYGCNGARGARAARATGGARMGNTGGATH GARMGNYTNTCNCARATHMGNMGNMGNAARYTNGARGGNGAYATHATG------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GAYGAYGAYGARGARAARGARAARGAYAAYMGNGARAARGARMGNAGYYTN GCNMGNGARMGNGARMGNMGNCARGARGARAARMGNCARMGNGARAARYTNGARAARYTN MGNGARCAR------------------------MGNGAYMGNGARMGNGARMGNGTNAAY GTNMGNGTNTCNMGNTCNAARTCNMGNTCNTCNTCNCCNGTNATHTCNMGNTCNMGNMGN MGNTCNMGNTCNMGNGARMGNGARMGNGARMGNAGYAGYMGNGAYMGNTCNMGNGARMGN MGNAARGARMGNGARATHGARGARGARGARGARYTNTAYGARMGNMGNAARYTNGARAAR AARYTNMGNGARAARGARGCNGCNTAYCARGARMGNYTNAARAAYTGGGARGGNMGNGAR MGNAARAARTCNMGNGARTAYGARAARGARAAYGARMGNGARGAYGARMGNAARGTNGAR GARGGNMGNGARGCNMGNMGNYTNAARGARTTYYTNGARGAYTAYGAYGAYYTNMGNGAY GAYCCNAARTTYTAYAARGGNAGYGCNYTNCARMGNMGNCARAARGARMGNGARAARGAR AARGARYTNGAYAAYMGNGAYMGNCARMGNGARAARGARGARTTYGARGARATHAARMGN AARYTNTTYGAYGARGGNCAYCCNGAYGCNGARACNGARGTNGCNMGNATGGARMGNGAR MGNGARGARCAYYTNCARCCNMGNYTNCAYYTNCARGARYTNAARCARCCNCCNCARCCN CCNGGNCCNGARGARTCNGCNTCNGAYGARGARCCN---------------CCNGGNCCN YTNGARATHCAYCARGCNTCNCCNAARCARTCNGAYTAYCARCARTCNMGNAAYATHTCN ---------------AAYAAYGCNCAYCAYCARCARCAYATHCCNGTNCCNGARCARMGN GCNTCNCCNTCNYTNTCNACNTCNCCNATHTCNACNGAYTCNMGNGTN---AGYGCNCCN GGNYTNTGYATGGAYGARTCNTCNCARTCNTCNYTNCCN------ACNGCNCCNCCNTCN TCNTAYGARGAR---AGYMGNYTNGGNACNAGYACNACN--------------------- ACNYTNAGYYTNGCNCCNGGNGCNAGYCCNGAYTCNTCNAGYYTNCCNGGNGCNACNAAY GTNTCNGAYGGNAARMGNAARAARYTNACNGTNGGNGAYGTNTTYAAYCARGAYGAYGAY GAYAGYAAYGARCCNAARAARMGNAARYTNATHCCNYTNGAYTAYGAYGAYGAYAARTCN ACNCCNACNGARAARAARGGNGCNACNGCNGARGARAARMGNCARAARATHAARCARYTN ATHGARAAYATHCCNACNGCNAARGAYGARYTNTAYGCNTAYACNGTNGAYTGGGAYATH GTNGAYCARGGNYTNATGGAYAARMGNATHAARCCNTGGGTNACNAARAARATHGTNGAR TAYATHGGNGARGARGARCCNACNYTNACNGARTTYATHTGYCARAARGTNATHGCNMGN AGYACNCCNCARAGYATHCARAAYGAYGTNGCNATGATHYTNGAYGARGARGCNGARGTN TTYGTNGTNAARATGTGGMGNYTNYTNGTNTAYGARACNGARGCNAARAARATGGGNYTN GTNAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGTTYGGNGGNATGMGNAARGGN TTYYTNTTYGGNAGYTCNAGYAARCARCCNTCNAARACNMGNTCNGAYGAYACNAARAAY GTNGGNAARGAYACNAARTCNAARTCNGCNCARATHAGYCCN------------------ GCNACNGAYTCNMGNCCNAARGARGARATGCCNTAYATHACNCCNTCNGGNAARACNGAR TCNGGNYTNACNTTYACNGARGTNCARCARGCNATGTCNGARGCNAARGGNYTNYTNGAY AAYCARGAYTGGATHACNGAYGAYYTNYTNAAYAARATHGARAARAAYGAYAAYYTNGTN AARMGNTTYAGYGAYCCNCAYTTYATGTCNGCNYTNCARGARTTYCARACNAAYCCNCAR GCNGCNATGGARAARTAYAARGGNAAYACNGARGTNGARAARTTYYTNYTNGAYTTYTGY GGNYTNYTNGGNAAYCAYTTYACNGAYYTNGGNAGYAGYGAYGCNAARTCNCCNTCNCAR CARCARCARCCNAAYTCNCCNTCNTCNACNGCNACNGCNTCNAARTCNMGNACNGARAAR ACNTCNGCNGCNAARATHGTNGARYTNGAYGAYGGNGTNGGNAAYGARAAYAARCCNCCN AARATHGTNGARATH------------------------------------TCNGGNGAR AARGAYAAYGGNAGYAAYGCNACNGAYCARATGAAYACNGTNCCNCAYCARAARTCNACN TCNCARATHMGNGTN--------------------------------------------- ---CAYGAYCCNCARAAYGGNGCNGAYATHCARGARYTNCCN---------------CCN GCNACNGAYGAYGAYGTNAARGARGTNYTNAAYGAYCCNAARGTNATGGARACNYTNATG GAYCCNAARGTNATGGGNYTNATHAARATGYTNMGNGARGAYCCNGCNAARGGNCARMGN ATHGTNGAYAARGCNGAYTCNGAYYTNAARGAYAARATHCARTTYYTNGTNTCNMGNGGN YTNYTNCARTTYCAR------CAYAAYMGNCCNAARCCNACNAAYGTNGCNTCNYTNYTN YTNCARGAYCAYGARAAYGARATGYTNTTYCARACNYTNGGNMGNYTNTGYGTNACNYTN GCNACNGGNGTNGTNCARYTNTAYYTNGCNGAYCARTCNGAYMGNACNMGNTGGAAYAAR MGNTGYTGYGGNGTNGCNTGYTTYGTNAARGAYAGYTCNAARAARTCNTTYTTYATHAAR GTNTAYGAYATHAARAARCARCARYTNYTNTGGGARCARGARYTNTAYAAYCARTTYGTN TAYAARAGYCCNMGNGARTAYTTYCAYACNTTYGARGCNCAYAAYTGYCARGCNGGNATG AAYTTYGCNGAYGARGAYGARGCNAAYAARTTYAARAARGCNGTNGARGGNAARYTNAAY GAYMGNMGNCARAARAARATGGARMGNMGNCARAARTCNGTNTCNCAYAARCAY------ ------------AAYGTNGAYCARAGYTCNAAYGCNCCNCARMGNATG---GGNCARAGY GCNGCNCCNGCNACNMGNGCNGTNAARYTNGAYGCNAAYMGNAGYAAYACNACNAAYACN ACNAAYACNCARAARAARGARAARGAYAARAARAARGAYGCNAARAARAARYTNACNAAR GCNGAYATHGGNACNCCNTCNAAYTTYGTNCAYGTNAGYCAYGTNGGNTGGGAYCCNGAY AARGGNTTYGAYATGAAYAAYYTNGARCCNGAYATGCARACNYTNTTYCARTCNGTNGGN ATHAARCCNGARGAYGTNGTNGAYAARGARACNGTNGARTTYATHTAYGAYTTYGTNGAR AARMGNGGNGGNATGGARGCNTTYAGYAARGARYTNMGNAGYAAYAAR------------ ---CCNCCNCCNCCNCCNGCNATHGGNGGNGGNAGYATHCARCCNCCNCCNCCNCCNGCN MGNCCNCCNGGNGCNYTNCCNCCNMGNAGYGTNGCN---------CCNCCNCCNCCNCCN TCNMGNGGNCCNCCNCCNCCNGGNATGMGNGGNGCNGCNCCNCCNCCNCCNCCNTCNMGN GTNATGCCNACNCCNCCNMGNGCNCCNGCNGCNGCNCCNCCNCCNCCNCCNCCNCCNTCN TCNGTNCCNCCNCCNCCNCCNGGNTCNGCNCCNCCNCCNCCN---------CCNCCNCCN CCNCCNCCNCCNTCNGGNGGN------------------------CCNCCNCCNCCNCCN CCNCCNGGNCCNCCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYGGNGAYCCNYTNAARCARGARYTNGTN GARMGNTAYTCNATHAGYGTNATHCCNAARYTNATHGTNATHCARCCNGAYGGNGARGTN ATHAGYAGYAARGGNMGNAARGAYGTNCARGAYMGNGGNGTNATHTGYATGMGNATGTGG CARGCNGGNTTYGAYMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AAYATHCCNATH CCNAARCCNGAYTAYTGGGGNGGNTTYMGNGTNATHCCNCAYMGNTAYGARTTYTGGCAR GGNCARAGYAAYMGNATHCAYGAYMGNATHGTNTTYMGNAARCCNGARGARGGNGARACN ATHGAYCCNACNGTNACNTTYCARGGNYTNGAYGGNTGGGTNTAYGARMGNYTNCARCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CCNTTYAARAAYCAYTCNMGNGGNTTYMGNAAYMGNMGNAARTCNGAYGAY GTNTCNACNGTNGARTCNCARGGN---------AAYTCNTTYTCNGTNYTNAARTCNACN GCNTTYGTNACNGGNGTNTGYAGYTGYAGYTTYGTNGGNGCNATGATHTGGAAYTAYGAR AAYGTNMGNCARGTNTAYAARGAYYTN------GCNACNGARAARCCNGCNCCNCAYCAR MGNCCNGCNTTYGARAARGCNTTYGGNTTYMGNCARCAYYTNAAYGCNATGTGGTCNAGY YTNGAYACNTCNACNAARATHACNTTYGGNATHATHGCNATHAAYGCNGCNGTNTGGGCN YTNTGGAARGTNCCNMGNYTNCARCAYGGNATGATHMGNTTYTTYTCNTCNTCNGCNGCN CAYCCNMGNTCNTCNATGGTNYTNAGYAGYTTYAGYCAYATHAGYTTYYTNCAYTTYGCN GTNAAYATGTAYGTNYTNATGTCNTTYGCNCCNGTNGCNACNMGNYTNTTYGGNCAYGCN CARTTYTCNGCNTTYTAYATHAGYGCNGGNACNATHTCNGCNTTYGCNAGYATHYTNTGY CARCAYYTNYTNMGNMGNCCNYTNTCNATHTCNGTNGGNGCNTCNGGNGCNATHATGGGN YTNYTNGGNGTNACNGGNGTNGTNTAYCCNAAYGCNGARYTNCARATHGCNTTYGTNTCN GARATHTTYCCNCAYTCNTTYTCNGCNCARACNGGNATHAARGCNYTNATHYTNTTYGAY YTNYTNGGNYTNTTYATGGGNTGGMGNTTYYTNGAYCAYGCNGGNCAYYTNGGNGGNATG TTYTTYGGNATHYTNTAYGCNAARTAYGGNAAYAARTTYATHTGGGGNAAYMGNGAYCAY ATHGTNAARTAYTGGCAYGAYATHMGNGGNAARCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNCCNGCNYTNCARGAYTAYGAYTTYCARACNGARCCNGGNGGNCAYTCNYTNGAR AARGCNYTNCAYCAYYTNGAYMGNYTNAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNAARCARGGNGTNCCNGAYCCNTAY AGYGGNGTNGCNAAYAGYTCNATGACNGARTGGGARAARGCNMGNGARMGNGARGARTTY AGYMGNTCNGCNAARYTNTTYMGNCCNATGTCNGCNATGATGGCNACNMGNTTYGTNCAR GGNGCNATGATGGAYGGNGGNACNGARGAYTCNAARATGGARGARAARGARCAYCARTCN GAYGARGCNAARGCNGCNGARATGAARATGTTYGGNAARYTNACNMGNGARGARTTYGAR TGGCAYCCNGAYAARYTNGTNTGYMGNMGNTTYAAYGTNCCNAAYCCNTAYCCNGGNTCN GAYATHGTNGGNYTNCCNAAYGTNAARMGNGAYAARTAYTCNATHTTYAAYTTYYTNTCN ATGGGNGAYTTYCARCCNAARGAYGAYATGGTNGAYAARGCNGARTCNMGNCARMGNCAY MGNGARCCNGARAARGARACNATHCCNAAYACN------CCNGCN------AARAARAAR GCNACNYTNGCNTCNATHTTYAARGTNYTNGAYGAYCCNGAYTTYCAYAARCCNGCNYTN AARGARACNACNGTNGARGTNGCNAARGCNGARACNGAYGAYGTNGGNGAY--------- ------------GAYGARAARGARGARGARGARGCNGCNGCNGAYGTNGAYYTNTTYMGN GCNATHTTYAARAAYTCNGAYTCNGARGAYACNGARGAR------AARGARGAYGAYAAY AAYTCNATGAGYGARGAYGAYGAYGARAAYGTNAAYAARAAYGAYGAYGTNGAYGAYYTN CCNGTNATHGTNAGYCAYGTNAARGARYTNACNGGNGARAGYGARGGNYTNMGNGTNAAY AARGARMGNGAYGARGAYACNAGYACNCCNATGAARACNCCNGTNCARCCNGCNATGAGY ---------------------------------------AAYGCNTTYGGNAGYGTNTTY MGNGAYCCNGGNGTNAARTCNMGNMGNTCNGARTCNMGNTGGGGNCCNAARTCNATHTTY AGYGTNYTNGAYGAYATHGARACNGARAGYCARAAYGAYGAYGAYGTN------------ ---------------------------------------------TAYGGNCCNGCNYTN CCNCCNCCNCCNTCNTCNGARCCNTCN---TCNCARTCNCARCCNGCNCARGAYMGNGTN AARTAYGTNGARTCNCARMGNGCNGTNMGNCAYCAYCARTAYMGNGAYAARTAYAARCAY AARAARGARAARAARAARMGNTCNAARCAYAARAARGARAARAARCAYAARAAR---AGY AARAARTCNTCNAARTCNAARAARACNAARCCNGAYAAYTCNAGYAGYGARGCNGAYACN GARACNTGYGAYGARTCNGAYGTNTCNGAYAGYGARYTNYTNGARMGNYTNAARCARGTN TCNMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNTCNTGYAARMGNYTNGCNCARCAYTCNTGY GTNGCNGAYGAYGGNTTYMGNAGYCCNCARGTNTCNATGYTNYTNGGNACNGAYGGNAAR GTNGTNCAYGTNGAYAAYGGNATHAARTAYAGYTTYGAYGTNACNAARTGYATGTTYAGY TCNGGNAAYGTNACNGARAARYTNMGNATHGCNGGNTGGGAYTGYTCNAAYGARACNGTN GTNGAYYTNTAYGCNGGNATHGGNTAYTTYACNYTNCCNTAYYTNGTNCAYGCNCARGCN AAYCAYGTNCAYGCNTGYGARTGGAAYCCNGAYGCNGTNGCNGCNYTNMGNAAYAAYYTN TCNYTNAAYMGNGTNCARGARMGNTGYACNATHCAYGARGGNGAYAAYMGNCARYTNAAR YTNTCNGGNGTNGCNGAYMGNGTNAAYYTNGGNYTNATHCCNAGYAGYCARGAYGGNTGG CCNGTNGCNGTNMGNGTNYTNAARCCNAGYGGNGGNGTNYTNCAYATHCAYGCNAAYGTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNATHTGGCCNAGYGCN GAYGGNGCN---CCNTCNGARGTNTCNYTNYTNYTNGGNYTNACNATHYTNTCNYTNYTN GTNATGCCNTTYTTYTGYGTNGCNTCNTTYATHAARGTNGGNAARYTNGCNAAYGAYGGN GTNAARYTNGGNMGNGAYCARGAYGARAARCCNGCNTCNGGNGAYGAYGAYTCNGCNAAR GAYAARGARTTYATHACNAARAARAARGCNAARTAYYTNTGGAARCAYTTYTGYCCNGTN GCNCARACNYTNCAYYTNATHGCNGCNTTYYTNYTNYTNYTNCCNGARGTNYTNYTNACN GCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNYTNGGNCARTAYATHGTNMGNGTN AGYGGNGCNCARMGNATGGTNGGNMGNATHGTNGARACNGARGCNTAYCARGGNCCNGAR GAYAARGCNGCNCAYAGYTAYCARGGNAARAARACNCCNAARAAYGARGCNATGTTYATG TGYCCNGGNACNTGYTAYGTNTAYAAYATHTAYGGNATGTAYTGYTGYATGAAYATHTCN AGYCARGARGAYGGNGCNGCNGTNYTNATHMGNGCNYTNGARCCNATHGARGGNCARGAY YTNATG---------MGNGARGGNMGNAAYAAYAAR------AGYACNAARCCNYTNAAR GARAARGAYYTNGCNAAYGGNCCNTCNAARYTNTGYCARGCNYTNCAYATHACNAARAAY GAYTTYAAYAARGTNGAYYTNACNTCNTCNAAYACNYTNTGGYTNGARACNGGNGAYTGY ATGGAYGAYAGYYTNGTNGTNTGYTGYCCNMGNATHAAYATHGGNTAYGCNGARGAYTGG AARGARAARCCNYTNMGNTTYTAYATHYTNGGNAAYTCNTGYGTNAGYGTNAARGAYAAR AARGCNGAR------------------AARAARTTYGTNTGYTAYTAYACNAAYTGGGCN CARTAYMGNCCNGGNTTYGCNAARTTYACNCCNAARAAYATHGAYCCNMGNYTNTGYACN CAYTTYCAYTAYGCNTTYGCNAARYTNTAYTCNAAYCAYACNYTNGCNCCNTAYGARTGG AAYGAYGARAGYACNCCNTGGATGGARGGNATGTAYGTNAARTTYACNAAYYTNAARCAR CARTAYCCNAAYYTNAARATGATGYTNTCNYTNGGNGGNTGGAAYYTNGCNTCNGGNCCN TTYACNMGNATGGCNCARTCNAARCARACNMGNAARGTNTTYATHGAYAGYGCNATHGTN TTYYTNMGNCAYTGGAAYTTYGAYGGNYTNGGNATHGAYTGGGARTAYCCNGGNTCNMGN GGNAGYCCNGCNGGNGAYAARGARAARTTYACNYTNYTNGTNCARGARACNATGGCNGCN TTYGARGAYGARTCNCARAGYACNAAYAARCCNMGNYTNYTNYTNTCNGCNGCNGTNTCN GCNGGNAARAGYACNATHGAYCARGCNTAYGARGTNCCNAARATHGCNAGYGCNGTNGAY TAYTTYGTNYTNATGACNTAYGAYTTYTTYGGNGCNTGGGAYCCNTAYACNGGNYTNGTN AGYCCNYTNTAYCCNCCNAARAAYGCNAAR---GGNYTNGAYGCNATHTTYAAYGTNCAR TAYGCNACNAAYTAYTGGGTNTCNAARGGNTGYCCNAARGAYAARYTNGTNGTNGGNGTN ATHTCNTAYGGNMGNTCNTAYACNYTNACNAAYACNTCNGAYACNGGNYTNAARGCNCCN ACNAAYGGNCCNGGNACNAGYGGNACNTAYACNMGNGARGCNGGNTTYYTNTCNTAYTAY GARGTNTGYAGYATGATHCARMGNGGNGCNAARATHGTNCAYYTNGARGAYGARAARGTN CCNTAYYTNGTNYTNGGNAAYCARTGGGTNAGYTAYGARGAYCARTCNAGYATHMGNATH AARTCNAARTAYATHYTNGAYGARGGNTTYGCNGGNGCNGCNATHTGGAGYGTNCCNYTN GAYGAYTTYACNGGNAGYGTNTGYGGNCARGGNGCNTAYCCNYTNATGACNATHGTNTCN AAYGCNATG--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CCNYTNCARGTNCCNGARMGNTAYACNAARMGNTAYCCNTTYATHMGNAAYMGNAARMGN ---------------------CARATHTAYGCN--------------------------- ------------------------------------GGNATGGTNTCNGTNYTNGAYGAR GGNGTNGGNAAYYTNACNCARGCNYTNAARAARACNGGNYTNTGGGARAAYACNGTNGTN ATHTTYTCNACNGAYAAYGGNGGNCARATHCAYAAYGGNGGNAAYAAYTAYCCNYTNMGN GGNTGGAARGGNACNYTNTGGGARGGNGGNYTNCAYGGNGTNGGNTTYGTNACNGGNCCN AARGTNATGTCNCCNGGNACNGTNAAYMGNGARYTNATHCAYGTNTCNGAYTGGTAYCCN ACNYTNGTNAARYTNGCNGGNGGNAAYYTNAAYGGNACNAARCCNYTNGAYGGNTAYGAY CARTGGGARACNATHAGYTCNGGNACNYTNAGYAARMGNAARGTNYTNYTNCAYAAYATH GAYATHYTNCAYGGNAARAARGGNAAYCARYTNTAYAAYGAYACNTTYGAYACNMGNGTN MGNGCNGCNATHMGNATGGGNGAYATGAARYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CAYGTNTAYGARTCN AAYYTNGTNGTNCCNCCNGGNAAYGAYAGYTTYGCNGCNTTYYTNYTNGCNAAYAARAAY GARTGGATHCAYYTNMGNYTNCARAAYGCNTGGGARGGNGAYGTNACNYTNACNAAYATH GARYTNCCNATHTGGGARGTNTCNCCNAGYMGNGARYTNGTNTAYGARCCNGGNCARAAY ATHAGYGTNAARATGYTNCARAARMGNGGNCCNGGNGAYYTNMGNMGNGAYGAYAAYTAY MGNYTNGARTAYAAYTTYYTNYTNCCNGGNAGYGCNGARGTNATHTCNATHTTYAAYCAY AARGAYGAYTTYTTYACNAARGARAARGTNGARAARTTYYTNGAYMGNCARMGNTTYGAR GCNGARYTNAAYACNGAYGARTAYCCNYTNATGGGNYTNTTYGARYTNACNACNGGNACN CCNAGYGGNTTYGTNGCNATHGARTAYGGNCAR---------CARYTNGTNYTNMGNCCN TCNACNCARCARGGNGCNTTYCCNTAYGGNCARYTNTAYATGCCNGAYTAYAAYTGGYTN GAYAARAAYGAYAAYGGNGARTAYGARAARTTYTGYGGNTAYGGNGARYTNTGYGGNATH CAYTGYAAYGTNGTNGGNGAYCARGTNACNACNYTNAARYTNTAYGARACNYTNAAYGGN CARACNAARYTNYTNCCNATGGTNACNYTNGGNGCNGARGAYCCNGGNTCNTAYMGNATH AGYACNATGMGNTCNAAYCCNGGNTCNCCNTCNGCNGTNACNTAYACNTGYGTNGGNTCN AAYGCNGTNGGNMGNMGNGTNTCNMGNAARGTNGTNGTNTAYACNGGNCARMGNGCNACN ATHGCNMGNAAYGARACNGGNYTNAARYTNYTNGARAAYGGNAAYGCNGTNGTNAAYTGY ACNGCNTCNGGNYTNCCNMGNCCNCARATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATHYTNGGNTCNGCNCCNAARTCNAGYGCNAARATHTAYGCNMGNGARCCN TTYGTNTGYCAYGAYGARTTYGTNTTYYTNGCNGCNGAYTTYCARCARATHGARYTNMGN YTNYTNGCNCAYYTNTCNAAYGAYAARGTNYTNYTNTCNYTNTTYTGGAAYCCNGCNAGY ATHGAYATHGCNGAYTAYYTNAARGTNAARCCNAAYGARGCNAARGARATHATGAAYAAR TTYYTNGCNMGNTTYCCNGCNATHGAYTCNTTYACNAARGARTGYTGYTCNTAYGCNMGN GAYAAYGGNTTYACNAARACNATHTGYGGNMGNMGNMGNTAYTTYCCNTAYATHAAYAGY CCNTCNCCNGCNYTNMGNTCNCARGCNCARMGNCARGCNGTNAAYTTYTGYGTNCARGGN TCNGCNGCNGAYATHTGYAARYTNGCNATGYTNGARGTNGARTCNAGYYTNAGYCARCAY CCNCAYYTNAARTGYMGNYTNYTNYTNCARATHCAYGAYGARYTNYTNTGGGARGTNGCN GARGAYCARGTNTAYGARGTNAARGGNATHATHGARGAYGTNATGGARAAYGCNAARACN YTNTGYMGNAARTTYTGYTCNYTNCARGTNCCNYTNACNGTNTCNTTYAGYAARGGNAAR TCNTGGGCNCAYYTNAAYCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARYTNAGYCCNCAYGGNCARCAYYTNYTNYTNYTNYTN AAYGGNMGNMGNAAYATGGTNAARGAYAARYTNCCNYTNAAYTTYGTNGCNGCNATHCAY GGNGAYAGYTGGACNGGNGARGCNACNATHCCNAARGAYTAYYTNCCNCCNTCNGTNACN AARTTYAAYGCNTAYGCNATHCAYGGNGARGGNGAYGARMGNCARTAYGARTCNYTNTAY CCNGTNAARGARYTNAAR---------GAYGGNATGCARCCNGAYTTYCAYMGNYTNGAR YTNTTYGARCCNATHGAYATGAGYTCNATHYTNACNGAYTAYATHCCNTCNCAYACNTCN ACNYTNTGGGCNGARGTNYTNAARTCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TCNAGYCARYTNYTNGCNTAYATHAARMGNYTNGTNYTN TCNYTNACNGCNCARACNGGNAGYCARGARTTYGCNMGNTTYTTYCAYMGNCARYTNTCN TCNATHYTNCARGAYACNYTNGARAARTAYGARGGNMGNAARATGMGNGARTGYGGNGAR GAYYTNYTNGTNGARATHTCNGAYGTNYTNTTYAAYGARYTNGCNTTYTTYMGNYTNATG CARGAYATHGARGAYCCNAAYGARGTNGARAARYTNMGNAGYACNACNGGNYTNTCNTAY CARGGNMGNAARCAYGAYGAYMGNGGNGARGAYGARGAYAGYAGYTTYAAYGARGAYGGN GARGTNGAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARTTYYTNTCNGARAAYAAYATH CCNATHAAYGARGARGAY---------YTNATHYTNGGNATGGGNAAYAARTCNGGNCAR AGYCCNCCNCARACNGGNGTNAAYACNCCNCCNCAYCCN---ACNATGGAYTCNCCNMGN CARTAYYTNMGNACNCCNCCNGTNAGYCCNTCNCARTTYATHACNGGNACNGTNATGGCN CCNGTNACNCCNTAYCCNTCNAARTCNCCNGGNCAYGARGCNAGYAGYTCNACNCCNCCN TCNCCNGGNAGYCCN---TTYAARGTNGAYTTYCARGTNTCNGARCARGAYYTNGCNYTN ACNACNATHCCNGAYTAYAARGAYCCNMGNTAYTAYTCNAAYGCNCARGGNTGGAAYMGN GAYGAYCAYMGNCCNAARYTNGGNGCNAGY------------TTYGAYCCNMGNAARMGN AAYTTYTCNGARGARGARYTNAARCCNCARCCNATHATGAARAARTCNAARAARATHTTY GTNCCNGARGAYYTNAARGAYGAYAARTAYTGGGCNMGNMGNGTNAARAAYAAYTAYGCN GCNAARMGNTCNMGNGAYGCNMGNMGNGTNAARGARAAYCARATHGCNYTNMGNGCNGCN TAYYTNGARAARGARAAYAARTGYYTNAARGAYGARATGTCNAARYTNMGNAARGARAAY GCNMGNYTNAARAGYGTNGTNGARAARTAYGARGGNAGYGCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------MGNMGNCCNCARACNTCNCAY GTN---MGNTAYGCNCCNAAYACNTAYAAYGAYCCNGGNMGNTAYGGNAARGGNGAYYTN TAYGAYGTNMGNGARGGNGAYGGNGTNAARAARCCNMGNCCNGTNAGYGCNTCNAGYYTN MGNGARGGNGAYGCNGCNMGNGCNMGNCCNCAYTCNGGNTCNATGGTNMGNGGNGAYMGN GGNGCNCCNACNTTYYTNACNCARAARAAYGARMGNTCNYTNAARTAYGARTCNACNAAR CCNGTNTAYGTNCAYCCNAAR------CARGCNAARAAYMGNMGNAAYTCNGAYGGNCAR GTNTCNAARYTNACNMGNTCNAAYAGYCAYCCNGGNYTNATGTCNCARACNGAYGTNATH AGYGCNTCNAGYGCNTCNAARATHCARACNCAYACNGGNTCNGCNAAYCAY--------- ------CARATHGCNTCNGAYGGNAAYTGYGGNACNGCNATGGTNGARAAYGAYATHGGN TAYGTNGAY---------------------------GAYTTYGCNAAYGTNGARACNAAR CCNCCNATHTCNATHMGNGTNAARTCNGCNCAYTGYMGNMGNCCNGCNCAYATHGAYAAR TTYGCNGAYGARGARMGNGCNYTNMGNGARATGGARGCNGAYTTYAARAARACNGCNATH ACNYTNCARAARAARYTNGGNATHGARGAYACNGGNATHATHYTNYTNGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNTGYGAYMGNCAYYTNATGGGNYTNGCNYTNATHGCNAARGARGARAAY YTNCCNATHCCNATGYTNTTYCARGAYCCNGCNTTYGTNAARAGYGGNGGNGGNGGNAAY TAYYTNYTNTCNACNAGYACNATHGGNTAYACNTCNATHATGGGNGGNGTNYTNCCNATG TGYGARAAYTGYTAYGGNTGYTTYTAYMGNATHGGNGAYGAYAARYTNACNTTYTTYATH TCNACNTGGAAYTCNGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CCNAGYTTYGAYTAYMGNATHGARTGYATHTGYACNAARGAYAGYCARGAR ATHACNGAYATHGAYMGNGARGAYATGYTNMGNGCNGTNGTNGAYGGNGAYGARGARYTN ATHYTNATHACNCAYGGNACNGAYACNYTNTGYGAYACNGCNMGNTTYYTNGTNMGNGCN GGNGTNGGNCARGGNTCNYTNTTYGARCCNGGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AAYACNAAYGCNTCNAAYACNAGYTCNCCNTCNTCNMGNAAY CAY------AAYGGNGAYAARACNAARAAYGGNACNGCNGCNAAYAGYCARGGNTCNGTN GTNTAYCCNGARGARAAYACNCARCARTCNATHGGNTCNTAYGGNTCNGARAAYYTNAAY GARGAYTCNAAYATGTCNTTYCCNGARAAYAGYGARYTNAGYGARCAYGCNGAYCAYAAY GARTTYTCNCAYGAYAGYAAYGAYGCNGAYCCNGGNATGMGNGTNGCNATGAGYATGGTN GGNGAYGARGARGARGGN------------------------------------------ ------------------------------------------------------------ ATGTCNGAYAARCAYAGYTTYGGNGTNGCNCCNGTNACNTGYCAYGCNTTYAGYAARGAY MGNAAYGGNYTNGCNYTNTCNYTNAAYGAYTCNGAYGTNAARGTNTAYAARAARTCNGGN GCNAARTGGGAYGARCARGCNACNYTNAGYGARCAYGGNCARMGNGTNACNAGYATHGAY TGGGCNCCNGARAGYAAYMGNATHGTNACNTGYTCNGCNGAYMGNAAYGCNTTYGTNTGG AARYTNGARGARGGNAARTGGAARCARATGYTNGTNATHCCNMGNATHAAYMGNGCNGCN ACNTGYGTNMGNTGGTCNCCNAAYGARACNAARTTYGCNGTNGGNAGYGGNTCNMGNYTN ATHGCNGTNTGYTAYTAYGAYAAYGARAAYAAYTGGTGGGTNAGYMGNCAYATHAARAAR CCNATHMGNTCNACNGTNACNTGYYTNGAYTGGCAYCCNAAYAAYGTNYTNYTNGCNGCN GGNTCNACNGAYTTYAARTGYMGNGTNTTYTCNGCNTAYCARAARGARGTNGAYAGYAAR CCNTCNCCNTGYTCNTGGGGNTCNAARATGCCNTTYGGNGCNYTNATGGCNGARTTYAGY AAYGGNGGNGGNGGNTGGGTNCAYTCNGTNTCNTTYTCNGARAGYGGNAGYYTNGTNGCN TGGGTNGGNCAYGAYTCNAGYGTNTCNGTNGTNGAYTCNACNAAYGAYAAYGCNYTNGTN ATHATHAARGAYAGYTTYYTNCCNTTYATGAGYATHTCNTGGATHACNGARAAYTCNYTN GTNGCNGCNGGNTAYGAYTGYAAYCCNATGGTNTTYTCNTTYGGNGGNGGNAARATHACN TCNCARGGNAARYTNGAYGTNCCNCARGARAARGARTCNGGNACNATGAGYGCNATGAGY MGNTTYMGNAAYYTNGAYMGNAARGCNACNGCNAGYGAYAGYTCNTCNGARATGAARACN CARCAYCARAAYACNATHACNCARGTNTCNATHCAYACNGGNACNAARGGNAAYGCNTCN AARATHGCNACNAGYGGNGTNGAYGGNAAYYTNATHATHTGGGAYYTNAARYTNGAYAAY GCNGGNCAYGTNGCNGGNGGNGGNGAYAARAARATHGARATGGTNAARACNGAYTGGACN GCNAARTCNAARATHGGNTCNYTNGAYAARGTNAAYCAYCARCCNGGNGGNGGNGAYAAR AARATHGARGTNGTNAARACNGARTGGACNGCNAARTCNAARATHGGNTCNATGGAYAAR GTNAAYCAYMGNCCNGGNGGNGGNGAYGTNAARATHGARACNGCNAARACNGAYTGGAGY GCNAARTCNAARATHGGNTCNYTNGAYAARGTNCAYCAYCARCCNGGNGGNGGNGAYAAR AARATHGARACNGTNAARACNGARTGGAAYGTNCARTCNAARATHGGNTCNYTNGAYAAY GTNAARCAYCARCCNGGNGGNGGNGAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARATHTAYACNCCNTTYACNCAY YTNTCNGTNAARGCNYTNYTNAAYGAYCARCCNAGYCARTAYYTNATHGCNCCNAGYACN GARTGGYTNGARTAYTTYACNAAYTTYGCNAARATHTTYTAYTTYATHACNCCNAAYGTN GTNTCNTTYACNCAYYTNTTYGTNGGNTTYATHTCNGGNAARTTYGTNGCNTCNGARAAY YTNAAYGAYMGNMGNATHGCNGTNGTNYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GTNGCNTGG CAYATHCCNATGGAYYTNCAYCCNAGYCARTGGAARGARCCNACNAAYAARCCNAARMGN CAR---GARMGNGTN------------------------------GARAARTCNCAYMGN GCNCCNAARGGNGAYMGNMGNGCNGGNMGNGARTAYGARCAYMGN---ATHTGGACNAAR CCNACNCAYCCNCCNGGNATHCCNAARYTNCARTGGGARCARGTNGTNAGYAGYGAYGCN YTNGCNAGYAARATHAAYCAYTGGGARGTNGAYCCNYTNATGGAYMGNGTNCARTAYATH YTNAAYAARCARGAYGGNGARCARAGYMGNCARAGYAAYATGAGYGAYGAYGAYMGNAAR CCNTCNTCNAARYTNTCNYTNCARGARGCNTTYTAYTCNAARAARCARAAYTTYATHTCN AARTGYTCNGARMGNCARAARMGNYTNAARYTNGCNAARGARGAYMGNCAYYTNCARGAR TGYYTNMGNYTNGARMGNGARGCNATHTTYGCNGARCARGARMGNYTNGCNCCNCCNAAY YTNTAYGCNCAYCCNTAYAGYGAYAAYYTNTAYCARCCNAARCAYMGNATHYTNACNAAR CARGARATGAARACNATHACNGCNMGNMGNTAYAAYAARYTNCCNGARGTNGTNGARAAR AARGARGARGAYAARAARAARATHGARGCNMGNYTNAAYMGNYTNMGNGCNAAYYTNTTY AAYAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGATHGTNTAY AARTGYATHATHACNGGNGAYGARTTYTTYAAYGAYAGYTTYGAYTTYAARGAYGARGGN GGNTTYTAYGTNYTNAARGGNAARTTYGTNACNAARAAR---ACNGAYGAYATHGAYGAY TCNGCNYTNGGNGGNAAYCCNAGYGCNGARGARGCNTCNGAR---GGNACNGARGGNGGN ACNGARTCNGGNATHGAYATHGTNATGGCNAGYMGNYTNGTNGARACNGGNTTYGGNACN AARAARGARTAYCARGTNTAYATGAARGAYTAYACNAARYTNYTNTTYAARGCNYTNGAR GGNACN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CARAAYGARYTNATHAAYATHATGGARGARGTNAARGCNGGNAAYTTYACNATGCAR GAYGCNGARATGYTNTTYAARGCNTGGAARGARMGNTAYCARCARGGNAAYACNTCN--- AGYTTYMGNGARAARCARGCNGCNYTN--------------------------------- ---------------------------------------GTNGTNGTNGTNATHYTNYTN GCNAAYGTNGAYCCNGTNGCNATGACNTCNGAYCCNMGNGTNMGNYTNTGYGCNMGNGTN TGYTGGGAYGARAAYACNYTNGCNGARCARTGYGTNCAYGAYAARGGNTGYGAYGTNAAY ACNCARMGN------ACNMGNCARTAYGTNMGNTGYATHGAYCCNTGYTAYGTNCARGCN GCNTCNTGYTTYATGATGTGYCAYGGNAAYTAYCARMGNYTNTTYGAYGARTGYMGNCAR GARTGYACNAAYATGACNGGNTAYMGNTGYGARAAYAAYTGYTTYATGAAYMGNGCNYTN ACNYTNAAR------------------GAYTAYGAYGGNGCNGAYAGYTCNGAYYTNGAY GARAARGARCCNGAYGGNAAYGTNTCNGAYGARGAYACNGCNGAYGCNAGYGARACNGAR GARAARACNCCNAARGCNCAYAARCAYAGYYTNCCNAAYAGYGGNAGYCARMGNACNGAR ATHAARGARCARATGTAYCARGAYAARYTNGCNCARATHAARAARCARATHYTNATGYTN GARGARGGNACNYTNCARGARTTYYTNAARMGNACNAARAARATHGARATHAAYTAYMGN GARMGNYTNMGNCAYAAYGARATHTGYAARAARGTNGAYATHGARAARGCNGARMGNAAY TAYYTNATHGAYTGYGAYAAYGCNCARAARGARTTYGAR--------------------- ------------------------GARAARAARATHGAYYTNAARGARACNYTNATHAGY GAYYTNAARGARAARMGNGGNATGATHGARYTNGARMGNCARACNGTNGAYYTNAAYGGN GCNGAYTTYATGGARGTNAARCCNACNATGACNMGNAARYTNMGNMGNMGNCCNAAYGAY CCNATHCCNATHCCNGARAARMGNMGNAARCCNTCNCCNGCNCARGTNAAYATHYTNYTN GGNGAYGAYCARATHYTNTCNGAYYTNMGNYTNATHATGAARGTNAGYGGNAARCCNGTN GCNAARAARCAYGGNCCNGGNTCNCAYAGYCCNGTNACNGARTCNTCNTCNGARGTNMGN ATHGARGARGGNMGNYTNTGGTAYGAYAARAARTGGTTYCARMGNAAYAGYATGGTNCAR ATHGAYAAYAARGARGGNGGNTCNMGNATHTAYGGNACNATHACNAAYATHGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTTYMGNGCNGGNCCNGCNAARGCN MGNGGNGCNGAYAARACNAARCCNCCNGCNGCNCARACNCCNGTNATHGCNCAYGARATH GTNCCNGGNAARTTYAAYGARAAYGAYTGGAAYACNATGYTNGARMGNGAYGGNGGNGAY GARTTYGTNATGGAYATHATGGAYGAYYTNATGGGNMGNACNATGACNACNATHTAYGAR AARTAYATHGARMGNCARYTNYTNCCNTTYACNATHACNCARGCNMGNGAYGCNATHATH GARATHATHGARTGGCARTTYYTNGCNMGNGAYGARGGNGARGARAAYATHGAYGCNGAY YTNGGNTGGACNCARGAYGARGARCCNGARCCNGCNGARACNGAYTGYTGGGCNCARGGN TCNGTNCCNMGNAAYGTNGTNYTNGCNCCNACNCCN------------CCNYTNGARGAR ATHCARGARGARGTNGAR---GAYGTNTCNCARGARGCNGARAARGARGTNGARCCNCAR GARGARGTNTCNCARGARCCNCCNGARYTNGAYGAYGTNGTNTCNGARGCNGAYGARACN GCNGARATHATGGCNCARCARGARAAR---GAYGARAARGCNGTNGARAARGTNCCNTCN CCNCCNAAYTCNAARACNTCNYTNAARACNAARTTYMGNCCNTAYMGNGGNAARYTNAAR TCNGCNGGNGTNAGYAARATGACNGARTCNYTNGARGARMGNGARATGCARATGATHTAY GAYGARATHGTNGCNTCNATGCCNCCNAGYGARGAYAARCCNAGYACNYTNYTNAAYATG CCNGCNTCNTGYACNAGYATHYTNAARGTNCARACNGGNMGNCCNCCNGGNAAYAARGAY GTNGTNTAYGAYGAYYTNGGNAAYGTNATHGCNGTNATGAARYTNGAYGCNGARAARYTN CCNACNCAYAARGTNAAYGTNAARTAYCAYGTNGTNGAYCCNGCNGTNGARGCNGCNCAR GCNMGNYTNGAYGCNATGMGNAARGGNAARTCNACNGGNAGYAARATGMGNAARYTNAAR TCNATHAARAGYYTNAAYACNGAYTCNGTNGCNACNTCNTCNAARAAYAARGTNCARACN TCNACNGGNACNGTNGCNCCNYTNCCNCCNCCNYTN------------------------ ---------------------------------ATHGARGARATGGARGTNTCNCAYGGN GTNATHATHMGNGARGGNGGNMGNGTNAARAARGGNCCNGGNMGNTAYTAYMGNAARYTN GAYATHYTNGARGARCAYCARAARGGNATGAARCCNGTNAGYGTNCAYYTNACNAAYTCN GGNATHACNGTNAAYGAYYTNYTNGAYMGNAAYACNCCNATHYTNMGNCCNATHGGNGAY TCNTCNCCNYTNCCNCCNATHGTNCCNCARCCNCCNCCNCARCCNCARTCNCARGTNTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TAYAAYTTYGAYTTYGAYAAY YTNGAYGARTTYTCNAAYCCNTTYGARTCNAARAAY------AARYTNGGNTCNTCNCCN CCNATHCARTCNAAYGCNAAYTCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AAYCCNAARGGNYTNMGNCARATGYTNAAYYTNATHMGNMGNMGNTAYGAYAAYCCNCCN GTNGTNATHACNGGNAAYGGNGTNTGGGAYGAYGAYGGNGCNGTNGAYGAYGCNMGNTCN CAYTAYATHACNCARCAYGTNAAYGARGTNYTNAARGCNATHMGNATHGAYGGNTGYGAY GTNMGNGAYTAYACNTAYMGNTCNYTNTTYGAYGAYTAYGAYTAYAAYTAYGGNACNCAR MGNAARTTYGGNYTNGTNAARGTNGAYTTYTCNTCNCARGAYYTNAARMGNACNYTNAAR AARTCNGCNACNACNTAYAARGAYATHATHGCNAGYAARGGNATHYTNAAR--------- ------------------------------------------------------------ ------------------CCNATGTAYYTNTGYCCNTCNGTNYTNTGYYTNGTNGCNTTY ATHCAYCCNACNGCNATHAGYAAYCAYATHTGGCARTGYATHYTNTCNATHCARTTYGGN GTNGCNATHATHATGATGYTNTAYCARGTNTCNAARGTNTTYGCNATHTCNAGYCARATG GARGTNAAYCCNYTNGTNCAYGARGARGGNMGNGARATGGGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TGYAAYYTNTGYMGNAARACNTTYATHACNAARTCNGGNYTNGARMGNCAYATGAAYCAR CAYGCNGARCARAARGARTTYAARTGYAAYGTNTGYGGNAARTCNTTYCCNYTNAAYTGY YTNYTNAAYAARCAYGCNMGNTAYCAYGARATHGARAARCCNTTYAARTGYACNGTNTGY CARAARACNTTYGCNTAYAAYGCNGARYTNAAYMGNCAYATGAAYAARCAYACNGGNGAR AARCARTAYGARTGYGAYATHTGYCAYAARTCNTTYTAYAGYMGNTCNATHYTNACNACN CAYAARAARATHCAYACNGGNATHAARCCNTTYGARTGYGAYATHTGYCAYAARGCNTTY GGNYTNGTNCARCAYYTNGCNATHCAYAARMGNMGNCAYACNGGNGARAARCCNTTYAAR TGYACNGTNTGYGAYMGNGCNTTYTCNCAYAARGGNAAYYTNTCNAARCAYTTYAARGTN CAYACNGGNGARAARGCNTTYAARTGYGGNATHTGYGGNTGGTCNTTYTCNGARAAYTTY AAYYTNCARAARCAYATHGTNYTNCAYYTNGGNGARAARGCNTTYAARTGYGGNGTNTGY GGNMGNGGNTTYAAYMGNAARTAYAAYGTNACNATHCAYATGAARGTNCAYACNAARGAR AARCCNTAYAARTGYGAYGARTGYGGNAARGARTTYACNGAYAARACNTAYTTYMGNAAR CAYGTNAARTCNCAYGCNGGNAGYAARCCNCAYAARTGYGAYGARTGYAAYGARGCNTTY ACNTGYACNTCNAGYYTNGAYMGNCAYATGYTNACNCAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNTTYYTNMGNCARMGNACNGTNACNAAR TTYATH------AARGCNGTNAARTGGMGNCAYMGNTTYGTNGTNYTNGCNCARAAYGCN YTNTAYGTNTAYGARAAYGARATGTCNMGNTCNCCNGARACNTCNATHCCNYTNYTNGGN TAY---------ATHGCNGTNAARMGNGAYAARAGYCCNACNTGYACNTGGGTNTTYGCN YTNGTNCCNGGNGTNCCNTCNYTNACNCCNMGNGTNTTYGCNTGYTCNAAYGAYGCNGAY MGNAARGAYTGGATGMGNMGNATHAARMGNAAYYTNTAYTCNGCNAAYAAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TGYCCNMGNATHTAYTAYMGNTGYGARGAYCAYGTNTGGATHAARTCNTTYTGY GCNGCNGGNATHTAYAAYAARACNYTNAARGARTGYGTNCCNTTYTCNGAYAARTGYYTN ACNMGNYTNAARMGNCARGCNACNATGAARTGYGCNGAYCARTTYATHTGYCCNGCNGGN YTNACNCAYGARTTYACNTAYCCNGAYTGGGARAAYTGYGAYACNTTYTAYYTNTGYTCN AGYGGNGTNYTNACNAARCARTCNTGYAARGGNGAR---TAYAARTAYTAYAAYCCNMGN ACNYTNAGYTGYGARGARMGNGCNTCNAARACNAAYACNTGYATHMGNMGNGARTTYACN ------------------------------------------------------------ ------------------------------------------ATGGCNGAYTCNAARTCN AGYYTNGCNMGNGAYGGNACNATGCARGTNACNGCNAARGARGGNATHGAYTAYYTNAAR TCNGCNCAYAARGAYACNYTNYTNAARGTNCARGGNYTNGTNAARGAYAARCCNGCNGTN CARMGNGAYGGNACNATGGTNTCNACNGCNAARGARGCNGARMGNYTNYTNGAYGGNAAY AARCCNGAYGCNGAYGCNCARACNMGNGGNCARCARAARCARATHGAYGAYATHAARAAY GARAARTCNGARCCNMGNGCNAARAARGCNAARYTNGCNAARGAYGGNACNATGGCNGTN ACNGCNAARGARGCNAARGCNYTNYTNGCNGGNGARAARYTNGGNGAYACNMGNCARGAR ACNAARAAY---------AARCCNAARACNCCNYTNAARAARAAYATGACNATGGCNMGN ACNYTNGARGARGCNAARGGNGTNYTNGAYGGNAAYYTNGAYGTNAAYGARGGNMGNAAR ACNMGNTCNCARAGYMGNGGNGAYCCNCCNAARCCNCCNGTNAARMGNGCNGGNACNATG CARAARACNGCNAARGAYGGNAARGCNTTYYTNAAYMGNAGYAAR---GGNAARAARGCN GCNAARGTNGTNGARGARGARAARGARGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGCCNAGYYTNCCN YTNATH------------AARCARAGYATGGCNGCNGTNGGNGCNAAYACNGCNMGNACN YTN---------AARCARATGATGAARCCNCAYATHCCNATGATHAARTTYCCNMGNMGN GARGAYCCNAARYTNTCNGAR---GCNMGNCARGTNGTNGGNAAYCCNAAYTCNCARGAR TCNYTNACNAGYAGYGTNAAYCCNGGNAAYATHGTNACNTCNAGYTCNACNGGNTCNAAR TCNAARGGNCCNTAYATHGAYTCNTCNGARYTNCCNYTNMGNTTYAARMGNAARCCNYTN TCNYTNGARGARATGGARTTYATHGARAARGGNGGNCCNGTN------------------ ------------------------------------------------GTNGGNATHTGY GTNGARGCNTGYAGYATGAARATHMGNTCNATHGGNGTNAGYCARTGYCCNGAYGGNCAR GTNTGYGCNTCNAAYGGNTGYGGNCAYACNTGYCARCCNGTNAARAAYGCN---GCNYTN ATHAARTCNAARTGYTCNAARTAYATGTGYCAYYTNTTYTGYGARAAYGGNTTYAARACN GGNTCNGAYGGNTGYCCNATHTGYGTNTGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATHCAYACNCARGTNTCNCCNYTNYTNTTY CARGTNTCNGARAARYTNTGYGGNCARCCNATGAARAARMGNAARMGNYTNGAYCCNGCN YTNGCNGCNGCNAARACNCARAARAARATHAARAARATHGAYAARGARATHAARMGNYTN TCNMGNTTYGGNAARATHYTNAARCCNGTNGARGARATHGARGGNGAYMGNMGNAARYTN ATGGCNGCNGTNGARMGNMGNMGNGAYCCNACNGTNYTNACNTTYGARGARTCNGARTCN MGNGCNYTNYTNCAYAARGARTGGTCNTGGTAYMGNACNACNMGNTAYCAYGARATGATG ACNGTNTTYACNAARGTNGARGCNGCNCARCARGARGCNYTNGARGARYTNMGNGCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGGCNATHAGYGAYGARATGGARTGGAAYATHGAYATGGAR GTNAAYYTNTTYCAYGCNATGMGNGGNCAYAARCCNGCNGGNGTNAAYMGNCAYTTYCAR ATGATHGCNATHCAYGAYAARYTNAAYTCNTCNGCNAARAARATGACNTCNAGYGAYGTN TGGCARCAYYTNTCNACNYTNTAYGAYYTNCARGCNYTNAAYGARTCNGARATHGTNCCN TTYCCNAAYAARGCNGGNGAYTTYACNYTNGCNGAYAARGARATGYTNGARYTNTGYGCN AARTCNTTYCCNMGNTCNTCNTAYATHAAYACN---ATHTCNGAYTCNGCNAARGCNGAR GGNGCNGGNAARACNATHTCNAARYTNAGYAGYAARCCNGAYGCNAARCCNGTNCCNCAR ACNCCNAARYTNGARTCNAARGTNGARCCNAARAGYAGYACNTCNAARGCNGAYMGNCAR CCNATHACNCAYACNCCNTCNAGYMGNTCNGARTCNAARTCNTCNCAY------AGYAGY ------------AGYAGYAGYTCNAARTCNTCNCAYAAYACNTCNTCNTCNMGNGCNCCN TCNCCNTCNCCNAARMGNACNAARMGNACNMGNAAYGTNAAYTCNACNTCNGCNAGYCCN TCNACNCCNACNGARCCNCARTCNAARMGNMGNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARGAR AARTAYMGNGARGARYTNMGNMGNGCNGARAARGARMGNAARGARGCNYTNGARACNTCN ATGATGAARYTNMGNACNYTNGARGAYGARAAYGGNCARATGAARAAYAARYTNGAYGCN TCNAARACNMGNAAYAARGTNYTNTCNAAYGARYTNAARGGNYTNAARGCNCARGTNCAR ACNYTNYTNMGNAARAGYCARAAYGAYGAYGARTTYATHGARGCNYTNATGAARCARCAR AARCARYTNAARGARATGATGGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CAYAAYGTNGAYCARTCNGGNAARTCNATHATHGTN ACNMGNTCNGCNAARACNMGNATHCCNGARYTNAARYTNTAYGARGGNAARAARGARGAY GARGTNGGNGARAARCCNAARMGNAARATHYTNYTNAARAARCCNGCNAGYYTNGAYGAR AARCAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATGCARGCNYTNTCNAAYCARYTNATGMGNAGYAARYTNMGNCARCARAARAGY YTNGARATHAARYTNAAYCARMGNAARGCNAARYTNGARGARYTNAARCARAARMGNGCN GARYTNGGNGARGCNMGNCCNGAYAGYAGYAARAARGARAARTCNAAYATHGARACNAGY ------YTNGAYCARCARATHGCNAARGARGARGARGGNTTYGARGARGCNMGNCARTCN GCNGTNGCNGARYTNMGNMGNCARYTNTCNCARGARACNGARAAYGCNYTNAARCARCAR GAYGARGARATHGGNYTNYTNATHGGNMGNYTNCARGTNGGNCARGCNMGNMGNAARGCN GTNYTNGARAARCARGAYGCNGTNYTNAARGAYYTNCARGAYAAYYTNGARMGNCARGTN TCNTCNGCNAGYGGNYTNAARCCNTCNATGACNGAYACNATHYTNAAYCARCAYTAYGCN AARGTNTCNCAYYTNAAYGARCARYTNCARMGNCAYMGNGAYAAYCAYGARAARMGNATH YTNGARAARYTNTCNCAYAARMGNGCNGARAARGARGARATHATHGARTCNCARYTNGAR CARGARGCNCAYACNGARTAYACNGARAARCARAARMGNGGNGCNGGNTAYGCNAGYYTN GCNYTNATGCARTCNTTYYTNGARCARMGNCAYGCNAARGCNYTNGGNGARYTNGARYTN GARATGAARGCNGARYTNGARAARAGYAARAAYGARYTNAAYTCNCARYTNGARGTNGAR YTNMGNMGNGARYTNGAYGCNCARMGNCARAAYYTNYTNACNCARYTNGCNGCNGTNAGY GAYATHTCNGCNGCNGAYYTNCARAAYGCNGTNAARGCNAARGGNTCNGGNCARACNGAY AGYAARGTNGCNAARMGNYTNGCNAARGAYYTNAARGAYAAYGTNGARMGNGCNAARTCN TCNATG------AGYCAYGGNGAYCCNMGNGAYGAYGAYYTNGGNTTYMGNMGNAGYAAY ACNGAYTTYGAYAGYAARCARCCN---GCNMGNTCNAARGCNMGNAARGGNTCNGCNGCN TCNACNMGNCARMGNGGNAAYGCNMGNACNGCNTTYGTNGAYGARGARGARGAYGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNCARGTNATHGTNCAYMGNCCNYTNGARGCNYTNAAR YTNAARTTYGGNGAYGARGAYGCNATHACNAARACNCCNTCNGAY------------CCN ATGACNATHGAYCCNGGNAARTAYACNGTNAARTGYATHGGNGARGGNAGYAAYCCNGGN ACNGARGAYGTNCAYYTNTTYTTYAAYGGNGTNATGGTNCARCAYGARAARCCNGTNGTN GTNCAR---ATGGARACNCCNGARMGNAARTTYATGACNACNYTNACNGGNAAYGTNGAY ATHATGGTNAARGAYTCNGGNAAYGARTTYGAYTGYCARGCNAAR------GAYTCNGAR GGNCAYGCNTAYTCNACNAARYTNGCNATHGTNGTNAAYACNTAYGAYCCNGARGTNACN TGYAAYGAYACNGAYGCNTAYCAYGGNCARGAYAAYCCNATHATHTCNTGYACNGTNAAY CAYACNGAYATHGAYGTNGARGGNTAYMGNTAYCARATHGGNGARACNGGNGARATHTTY AARGARGGNGARCARCAYGARAAYAAYGTNAARGTNATHGTN---------TCNAAYGTN GCNGARGGNATHAGYATHGTNTCNYTNGAYYTNCAYAARGCNMGNAARGARTAYYTNGAY AARGAYTAYTAYATHYTNATHGAYATHAARGGNGGNCAYACNAGYAARGARAGYGTNMGN YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GCNAARGARYTNYTNAARTAYTCN GCNCARMGNGAYTAYAARATHCAYGCNTTYCARYTNGGNAAYGARCCNAAYGCNTTYAAR CAYAAYTTYAAYTTYAGYATHCCNGCNTCNACNYTNGTNACNGAYTTYCAYACNYTNAAR GAYGTNYTNAAYGARTAYCCNCARTAYMGNAGYAARAARYTNTAYGGNCCNGAYGTNACN AAYYTNGAYMGNCAYTCNTCNTCNMGNAAYTAYYTNCARGAYTTYGTNACNTCNGGNGGN TCNYTNGCNGTNAGYGARATHTCNYTNCAYCAYTAYTAYYTNAAYGGNMGNACNGCNAAR GTNAGYGAYTTYTAYGAYGTNTCNGTNYTNGAYTCNYTNGARMGNGARTTYAAYYTNGCN CARGGNATGGTNGGNGGNACNCCNATHMGNYTNACNGARACNTCNTCNTGYTAYGGNGGN GGNGCNCARGGNYTNTCNGAYGCNTAYGTNGCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNGTNGARGGNATGGTNMGNGGNCCNGGNCCNATGATH--- ---MGNCCNCAR------GCNCCNAARGAYAAYATHGTNMGNGGNCCNGGNCCNGCNAAY CCNGGNYTNTTYCARGGNCARCCNMGNGGNCCNGGNCCNGTNCCNGTNMGNCCNGGNYTN CCNGGNATHGGNGAR------------------------------------ACNCCNGTN AARATHTCNGAYCCNYTNGAYGAYCCNMGNTGGTCNGCNATGAARGGNYTNYTNATHTCN GAYGGNACNGARGARGTNGTNYTNGAYGAYAARCCNTTYGARYTNMGNATGGGNACNTCN MGNAARYTNCAYATGAAYAAYCARGTNTTYGARGTNGGNGTNGAYYTNAARGARMGNGGN ATHMGNGTNAAYGGNCARYTNYTNTAYACNYTNGGNGARCCNATHAARCARGTNAAYATH AAYGGNAARYTNACNMGNYTNTAYTAYCAYGGNYTNCCNAARCCNGTNTGGYTNGAYGGN CARTAYCAYGARATGMGNATHGAYGCNCCNCCNMGNAAYGTNATGATHGAYGAYAARCAR MGNGGNTTYCARATHGAYGGNMGNGAYATGATGYTNYTNATHGAYMGNATHGARAARGGN CCNTAYGGNGGNCCNCCNMGNAARATHYTNATHGCNGGNGCNGARCAYGAYATHAGYTTY CARTTYCCNCCNMGNCARATHYTNATHGAYGGNAARCCNTGYCARYTNAARYTNGAYAGY AARATHCCNTAYATHATGATHAAYGGNAARCCNCAYGGNATHMGNTTYGAYGGNGARCCN MGNACNGTNTAYATHAAYGAYCARCCNTTYACNATHCCNYTNGAYAARGCNGARAARATH MGNATHGGNCCNMGNCCNACNTAYATHGCNTTYGGNGGNCCNGCNCAYGARATHATHATH GAYGGNAARTGGTTYGARGTNCARTTYGAYAAYACNCCNAARAAYATHCARYTNGGNAAY MGNCAYTTYTGYGTNMGNATHCCNGGNCCNTCNCCNMGNGTNAARATHYTNGAYCARYTN CCNATGAAYTTYGAYGTNTCNMGNYTNYTNATHTCNCAYGCNGARAGYCARMGNAARATG CCN---TCNTCNGTNGTNCARCCN------GTNAAYCCN--------------------- ------------------------------------------------GCNATHCARACN AAYMGNCCNGGNAAYATGTCNACNATGAAYMGNGGNCARAAYCCNACNGCNCAR------ ------------------------------------MGNYTNYTNAAYCCNAAYCARGTN CAR------------------------GTNCARGGNACNYTNCAYGCNTCNATGGAYCAR AARCARGTNACNCCNCARGTNCARGGNTCNAAYATHTCNCARYTNTCNCARAAYATHTCN AAYYTNYTNCAR---CARCCNGGNATGGCNYTNGGNTTYGTNCAYCCNMGNATGATGMGN CCNCARGGNCAR------------------------AAYAAYCCNCARACNGGNGGN--- ------------YTNMGNGGNTCNYTNACNAAYATGATGAAYYTNCARTCNAAYTCNGGN GCNATGGGNACNATHGCNCAR---------GGNYTNYTNAAYMGNGTNGCNAAYACNGCN ATH---------------------------------AGYYTNTCNGCNATHTCNAAYATH GCNGAYTCNYTNGCNYTNGGNCARGCNATHGGNCARYTNCCNACNCARTCNGTNACNGAR CARCCNAAYACNGAYTCNGCNGCNATGGCNTCNGGNATGCARGGNGTNATGMGNCAYCCN ATGATGGCNTCNGGNAGYACNGGNYTNAGYGTNCCNTCNTCNGCNACNAGYGTNGGNAGY ACNGTNAGYTCNGARCCNGARCCNTAYYTNCCNCARATHTCNACNTCNGGNYTNTCNGCN CCNACNGGNYTNTCNGAYGCNATHACNACNTCNGCNACNAAYGARAGYACNTCNGCNGCN CCNACNTCNGCNCCN---GCNCCNGTNGAYATHAAYAGYYTNYTNAGYAAYYTNATHAAR GCNGGNYTNATHAARAAYGARCCNTCNTCNGARTCNGARTCNACNTCNAGYGTNATGCCN AARACNGARCCNACNATHGTNAARGCNGARAARCCN------------------------ ------------------AARGARGAYATHCCNGAYYTNTCNGAYTTYGAYACNGAYMGN ATGAARACNTTYTAYGARAGYGTNATHGARGARYTNCAYCARGGNATHCARTGYCAYACN TGYTCNGCNMGNTTYACNACNGAYGAYCARGARAARTAYMGNGCNCAYYTNGAYTGGCAY TTYMGNCARAAYAARYTNGARCARGARATGGTNAARGTNGCNAARAAYMGNAARTGGTTY TAYACNATHGCNGAYTGGATHCARTAYGARGARYTNGARGAYYTNGARGARAARTCNMGN AGYGARATHTTYGARCARATGMGNYTNGGNAGYGCNCAR---------CCNGTNACNGGN ATGGAYTCNYTNMGNYTNMGNGCNYTNGARGGNAARGARTAYGTNAARAAYCCNGTNGCN TCNGGNGTNGARGGNGARGAYGTNTGYGCNACNTGYGGNGAYCCNTTYGAYCARATGTGG AAYGARGARACNGARGARTGGATHYTNAARAAYACNATHAARGTNGAYGGNAARACNTAY CAYCCNATHTGYTTYGARGAYATGCAYGARACNCCNACNCCNATHTCNGTNGAYGGNCAR AAYCCNYTNGCNCAYGARATHTCNTCNCARATGGARYTNCCNATHAARACNGARAAYYTN TCNGTNAARCCNGARCCNGARAARATHGTNAGYTCNACNAGYGARGTNAGYAAYGTNATH CCNACNGARTGYAAYATHGCNATHAARCARGARGTNGTNGAYCCNGARGARCARGTNATH TCNTCN---GARTCNTCNCARATHAARTCNGARGTNATHGARGAYATHCCNGTNAARAGY GARTAYTGYGARCCNAARTCNCCNGTNTTYGTNTCNGCNYTNAAYAAYCCNGGNACNGGN ------------------------------------------------GTNMGNAAYGTN ATHTCNGTNTGYGCNGARGAYCCNAAYTCNCCNTGGGARATGGAYTCNAAYCCNACNCCN GARYTNTCNMGNACNCCNAGYCCNYTNCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGGGARGARGAYGARGAY GAYGTNGAYGARTTYACNGARGARGARATHGCNNNNGAYCCNTCNAARMGNATHYTNTGG GCNTCNGARAAYAAYAARYTNGAYATHGTNACNGARYTNYTNAGYACNAAYCCNGARYTN GTNTCNGTNTGYGAYAGYGAYTTYTAYACNCCNYTNCAYMGNTGYTCNTAYAAYAAYCAY CCNGARGTNGCNAARGTNYTNATHTCNCAYAARGCNAAYGTNCAYGCNAARACNGTNGAY GGNTGGCARCCNYTNCAYAGYGCNGCNMGNTGGAAYTCNGTNGARACNGCNCARYTNYTN ATHCAYAGYGGNGCNGAYGTNAAYGCNCARACNAAYGGNGGNYTNACNCCNYTNCAYATG GCNGCNTCNGARGTNGAYAAYGGNCARATGYTNGARYTNTTYYTNAAYAAYCCNTTYGTN GAYATHACNATHGTNTCNAARGTNGGNGARACNGCNAARCARATHTGYCARMGNACNAGY CCNCAYTAYCAYYTNTTYGARYTNAARGAYAARAGYYTNAAYCAYYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CAYGCN YTNTAYAGYAAYTTYAARATHGAYGGNGARMGNGAYMGNTAYMGNYTNCAYGTNTCNGGN TTYTCNGGNAGYGCNAARGAYTCNYTNAAYMGNCAYAAYAAYAARCCNTTYTCNACNGAR GAYMGNGAYCAYGAYAAYMGNMGNGAYGCNAGYTGYGCNGTNGARTGGGARGCNGGNTGG TGGTTYGAYAARTGYTGGTAYGCNYTNYTNAAYGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GARGARGCNGCNAARMGNYTNMGNAARMGNYTNYTNTAYGTNTTYMGN TAYGGNGTNYTNAARGARGGNYTNGAYGTNGAYTCNAAYGGNTAYGTNGAYYTNAARGAR GCNATGCARATHCCNYTNYTNTGYGARTAYTCNCARGARGAYGTNYTNAAYGARATHAAR AAYTCNATHTCNTAYMGNAARATGCAYMGNTTYGAYTGGAARGARCARAAYAARAARYTN TAYGTNMGNGCNGCNTAYYTNMGNAAYTTYGARAARAGYCCNTTYCAYMGNGGNACNAAR GTNAARACNYTNATGGARTCNTCNATGACNTGYGTNYTNGAYAAYYTNGAYATGTTYGAY YTNGARGARTTYCARGAYGARTAYACNATHAARYTNATGATHCAYMGNYTNAARMGNAAR AARGCNATHACNAAYAARGCNYTNTCNGTNYTNTTYGTNCCNACNYTNACNMGNATHGAR YTNGAYGGNATHTTYYTNACNAAYAAYACNYTNMGNYTNYTNTGGACNCARTGYCCNCAY YTNMGNGGNGTNAGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AGYTGYGAR GCNACNGAYAARTCNMGNGGNCARMGNGGNACNTGGMGNGARGARMGNAARYTNAAYAGY GARACNTTYGGNATHTCNGARAAYTAYMGNMGNAAYTAYMGNGGNMGNAGYAAYTGGMGN GGNGGNAAYCARMGNGGNGGNTGGMGNGGNMGNGGNMGNGGNGGNTAYGGNAAYMGNGAY GGNGGNTAYGGNGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYTAYCCNGCNGARGTNGARGTNTCN TAYGARGARTTYGGNCAYGTNAARCAYYTNYTNCCNCARTCNACNGTNCCNGARGTNCCN CARCAYTCNTCNTAYCCNACNCCNTCNGGNTGGATGCCNCCNAAYGAYGARATHMGNTCN CARCARCCNTAYYTNGTNMGNMGNACNAARAAYCAYGTNYTNCCNGTNTAYCCNGARCAR AAYGARGTNTGGGGNMGNATHYTNCAYCAYGAYACNATHAARAAYATHGARGGNGAYATH TGGGCNYTNGARTCNGARYTNMGNCAYTTYYTNCARGAYAARAAYAARGARGTNAARGTN ATHACNCARGTNCAYGARGTNAGYMGNTGYATHMGNATHMGNGGNCARAAYMGNGCNGAY ATHGCNCARTTYYTNATGGAYAARGGNATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARCCNTCNAGYGTN ACNACNACNAAYAGYAARCARMGNAARGTNGTNAGYMGNGAYTCN------------GCN AAYMGNATGAARCCNMGNCARGCNAARGAYATHMGNMGNGCNGCNCAYYTNGAYMGNMGN AAYAAYCARAARTAYGTNGAYATGATGMGNMGNMGNGGNYTNYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGTAYTTY GGNTCNAARTAYGTNTAYYTNGGNAAYCARAAYGARGAYGARGARGARGTNAARGTNTCN GARGTNGAYGAYGTNGTNYTNTCNGAYAGYGAYGTNAGYGAYGAYGAYGGNGARACNTGY YTNYTNGAYATHYTNGAYACNGCNGGNCARGARGARTAYTCNTCNYTNAARGAYCARTAY GTNMGNACNGGNAAYGGNTTYYTNATHATHTAYAGYATHACNGAYCARGARAGYTTYAAR GARGCNGARGCNATHTAYMGNTGGYTNAARMGNATGAAR---GARGAYGAYTGYCAYGTN ATHYTNGTNGCNAAYAARCARGAYYTNAARGGN------GARGCNACNGTNAGYGCNCAR GAYGGNCARGAYYTNGCNGGNMGNYTNGGNATHCCNTTYTTYGARACNTCNGCNYTNGAY GGNTCNGGNATHACNGAYGCNATGAARGGNYTNGTNMGNATHATHCCNMGNACNGGNAGY GAYTAYAARATHGTNATGYTNGGNAGYGGNGCNGTNGGNAARTCNAGYATHACNATHMGN TTYGTNAAYGGNACNTTYGTNGAYGAYTAYGAYCCNACNATHGARGAYTCNTAYMGNAAR ATGATHAAYGTNGAYGGNYTNCARGCNGTNAGYAARGAYACNMGNAARGCNGCNAARAAR GCNAARAARGCNAARAARAARCCNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CARGAYATHMGNYTNATHTCNACNTCNATHGAYTAY ATHCARGCNCAYAGYGGNAAYAGYCARGARGCNTGGMGNCCNCAYACNGCNATHCCNGAY AAYACNGARGAYGARAAYAARTCNGARGGNCCNTGYTTYATGTAYGGNGARMGNATHATH AGYMGNAARAARMGNMGNTAYGCNMGNCCNATGTCNGCNGTNGAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ACNGCNGCNGTN YTNYTNATGAARCAYACNACNAGYAARCARATHTTYACNMGNGARYTNMGNCARMGNCCN GGNGCNGCNAAYCAYTAYYTNCAYTAYYTNAARGARCAYTTYGAYTTYACNGARTAYATH GAYACNYTNTGYYTNYTNGGNMGNACNGARGARGCNGCNATHTTYAARTTYAARYTNGCN ATHCCNACNCCNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN ATHTCNTCNTTYACNGTNACNTCNMGNACNGGNCCNTCNAARACNCCNTGYCAYATGATG GAYMGNAARTCNACNTGGACNCAYGARGAYCCNMGNGGNTAYTTYTAYAARGGNAARTTY CARTCNTTYYTNTGYACNGGNCCNCARATGMGNAARTGYYTNGARAAYAARTAYATHGTN ATHYTNGGNGAYTCNAAYGCNMGNACNCAYTAYAGYAARYTNTCNGARGTNGTNAARTGY AARCARGTNYTNCCNTGGCCNAARGARAARTGGCAYGCNCCNYTNMGNTGYGARCAYAAR GARAARAAYATHACNATHACNTGGAAYCCNCAYTCNCARCCNTTYYTNTCNTAYCARGAY MGNTGGACNAARGAYGARGAYYTNATGTCNTCNACNATHATHYTNGAYAARYTNCCNAGY MGNCARCAYATHYTNCAYCAYTAYATHCAYATHTCNTTYTTYCAYATHAGYGTNTTYGAR GCNAARTAYMGNTCNYTNAARGARGCNGTNGTNMGNYTNYTNGCNMGNMGNCCNGAYACN MGNATHYTNATHMGNGGNAGYCAYATHGCNTGGATHGGNMGNGAYCCNCAYYTNGGNGGN GAYCAYYTNGGNAARTTYATHTCNMGNATHCARGARGAYGTNTTYAARGAYYTNCARGAY AARGTNTTYTTYGTNTCNTTYTGGGAYYTNACNATHGCNATHGARAAYAARAGYTTYCAY ATGTCNATHGARYTNGTNTCNAARTGYYTNGARATGGARGAYYTNGGNGAYACNTCNATH ACNAGYACNAARAAYAARAARAARAARAARCCNAARACNAAYGAYGCNATGCARATHATH AARACNGAYMGNCAYGGNGTNTGGAARGARYTNMGNAARGTNMGNAARCARCARYTNAAR GARATHACNAARAARAARAARAARGARAARTTYAARTCNGCNATHGARATHTAYAARGAR GARCAYGAYGTNGAYTAYACNGAYMGNAAYGTNGARACNYTNYTNAARATHTCNCARYTN GGNAARGTNAARGGNGAYGAYGCNCARAARATHYTNTAYCARCARCCNTGYMGNYTNTCN MGNGAYGTNAGYGARAARGARGARGARCCNGARCCNACNTCNATHTTYACNGARGARGAY TTYGCNAARTTYGCNAARGARTAYCAYCCN---ATGTCNATGCCNCAY------GCNCCN CCNYTNAGYGGNGGNAAYCAR---CAR---------------------GAYMGNCARAAY MGNAARYTNYTNYTNGARCAYATHCARGARCARAARAARMGNYTNCARCAYGGNCAYCAY TCN------AGYAGYCCN---ACNCCNTCNATGAGYACNAGYCCNGCNACNATGYTNAGY AAY---CCNTCNTCNGTNCCNGGNYTNACNGCNGCNGARTAYGCNACNATHAGYAAYCCN CARCARMGNGCNGCNYTNCARCAYGCNCAYGTNAAYTCNGTNGGNTAYTTYATHACNCAR GAYTCNTCNTTYGGNAAYYTNATHYTNCCNGTNYTNCCNMGNATHCCNGAYGTNAARACN GARACNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MGNGCNAARAAR GARGARGARGARMGNYTNGARMGNAARAARAARYTNGARATGATHATGAARMGNGTNAAR ACNGAY------------------CCNGCNTCN------CARGAYAGYTCNYTNAARYTN GARAGYCCNACNAARTCNACNGGNAGYTCNCCNAAYMGNAGYGCNYTNGCN--------- ---TCNCCNGARGTNCARGARYTNCCNCCNTTYGCNCARGARACNGARAAYTCNTCNGGN TCNGARGAYAAYACNAARCARGARGARGARGCNGTNCCNGTNGARAGYMGNGTNGARAAY CCNGARCCNGTNYTNACN------------------------------------------ ------------------------------------------------------------ ------------CCNGTNGTNMGNAGYGCNTCNTCNGGNGAYATHYTNGAYAGYGCNGCN GCNGAYGAYGAYAARAARGARATGGARAARGGNGAY---------AGYYTNACNGARYTN AGYACNCCNGTNMGN---CARTCNACNAAYGGNACNGCNTCNGARCCNTCNTCNGARGTN AARTCNMGNTTYAARTCNCCNYTNYTNCARCARYTNGTNGARAAYAARGGNGGN---TCN GAYTCNCCNGGNACNCCNAARTTYAARTCNCCNYTNYTNCARAAYYTNYTNGGNAARACN AARGTNGGNGCNMGNATGGGNYTNTCNGCNAGYATGGGNGAYYTNAGYYTNAAYAARGGN ------------------------------------GCNAAYCARTCNAGYACNAGYCCN TCNYTNAGYCCNGCNAGYTCNACNAARGARATHTCNAARGCNGGNCARGAYGARGAYAAR GAYGTNGAYGAR---TCNGTNGGNTCNTCNTCNGGNGTNTCNTCNTCNACNGCNACNGGN AAYGAYCARGARTCN------------TTYAGYCAYACNYTNACNAAYGGNGTNGCNGAR GAYAAYGTNACNACNGCNTAYAARTCNTCNCCNGARYTNATGATHGAYTCNGCNYTNGGN ACNAGYATHGARCCNCAR---------------GGNGGNGAYYTNGAYAAYACNGCNACN ACNAAYGGNCAYGCN------AARAAYAARCARGARATGGAYGAYTCNAGYATHGGNYTN CAYTAYCCNGARGARGAYAARACNYTNTCNGCNAGYGTNCCNGARCARTAYCARTCNGGN CARTCNTCNTCNCARGARGARACNGGNGGNAGYGGNCARTTYGARGAYTAYATHGARYTN YTNGAYTCNGGNAARGCNGGNGTNTCN---------YTNACNACNCCNATHATHGCNTTY GARGARAAYAGYMGNMGNACNGCNGAYGTNGGNGARTCNYTNTCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATHGGNTCNGAYGGNCARGTNYTNGARTCNCARTCNCCNTGGMGN YTNTCNTTYATHACNGAYGCNTTYTGGGGNATHATHAAYTTYATHGTNYTNTTYTTYCAR ACNATGTTYAAYCCNGAYAARAAYGCNAARGGNGAYAARTAYTCNACNGAYTAYMGNMGN CCNGGNGGNGGNGGNCCNCCNACNMGNMGNATGGGNGGNTTY------MGNMGNGGNGGN GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARTGGATHYTNTTYMGNTTYCCNAGYGGNGAYAAR ACNCCNYTNGARGGNYTNYTNTAYAARYTNYTNGARTAYGTNATHTTYYTNACNATGGCN GCNGTNGCNATGGARATGCARTGYMGNTAYYTNATGYTNYTNCARGGNACNTGGYTNTGG CARTGYGCNTTYATHYTNTGGMGNCCNTTYGGNYTNCCNTGGAARCAYGAYGAYGARGGN GAYYTNATHYTNGCNAGYYTNTTYTTYGCNTGGCAYTGYGGNGGNAAYATHATHGTNGTN YTNGGNATHTCNGGNGCNGTNACNTTYAARGGNAARAGY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYATH ACNAAYYTNGAYGTNGAYGTNATHGTNAAYGCNGCNAAYGGNMGNYTNGTNGCNAARGCN ATHGCNGARGCN---------------AARYTNCARGCNGARTGYGARAARCAYATHGAR CARAGYGGNACNATHTGYGARTCNTAYCAYTTYGCNTCNAGYGGNGGNAAYYTNAARGCN AARCARGTNTTYCAYGCNGTNGGNCCNAARTGGAARAAYTAYTCNTAYAGYGARGAYGAR TGYAARAARGTNYTNMGNCARACNYTNYTNMGNTGYYTNYTNCAYGCNGARAARGARGGN TTYMGNTCNATHGCNTTYCCNTCNATHAGYGCNGCNATHTTYGCNGTNCCNATHTAYATH TGYGTNGARAGYTAYYTNAAYGCNGTNYTNCAYTTYGARAARYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGAYCAYCARTAYGGNATHGCNGTN ACNAAYAARTTYGCNYTNTTYATHGAYGARGAYGARGAYCCNTTYGARGCNATHTCN--- ---------------AARAAYAARAGYAARAARGAYGCNGARAARAARGCNAARTCNAAR CARAARAARAAYACNCCNATHGTNGAYGARAARCCNGCNGCNCCNGARAAYGAYAGYACN AARAARAARGARGGNGGNGAYAARCCNGTN---TCNMGNCARGGNGAYMGNGGNMGNGGN AGYGCNMGNGGNMGNGARCCNMGNGARYTNMGNGARAAYGAYGGNGAYAARMGNCCNCCN MGNMGNCARGGN------------------------------------------------ ------CCNMGNGARAAYAARGARGGNMGNGTNGGNGAYGARAAYGTNCCNCCNGARTTY MGNGAYMGNCCN---GARGGNGGNTTYAARMGNMGNGARGAYMGN------GARGGNAGY GGNTTYGCNGGNGARMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNGGNMGNGGN GGNGARMGNGGNGCNAGYACNGGN------------GGNGGNTTYGGNCCNMGNGGNGAY MGNAARMGNGARTTYGAYMGNCAYAGYGGNACNGAYMGNACNGGNATHAARTCNGTNGAR AARAARGARGGNGGNGGNGCNCAYAAYTGGGGNAGYTTYMGNGAYGAYATHGARGARCAR GGNCARGTNAAYGCNTCNGARGARTCNGGNGARTGGGGNAAYCARCCNGAR--------- AARAGYGGNGAYYTNAAYGARAGYGTNGARGCNGARAAYGTNCCNGARGARGARGCNCAR CCNCARCARATGACNYTNGAYGARTGGAARGCNYTNMGNACN---CARAGYAARCCNAAR CCNGARTTYAAYACNMGNCARGCNGGNGARGGNGTNGAYTCNGCNCARTGGAARAARGGN GTNGARTAYCARAARAARCARGARGCNTCNGAYGARGAYGCNGAYTAYGARGARAGYGAR CAYATHGAYCAYCAYAGYMGNAAY---------AGYAARCARYTNGTNACNGAYATHMGN ATHACNTTYAAYGAYAAYCCNMGNMGNGGNMGNGGNMGN---MGNGGNGGNMGNGGNGGN ATGGARMGNGGNGCN---------------------GGNMGNGGNGGNMGN------GGN AGYGCNMGNGGNTTYGGNGGNAAYAARAARGARGCNGCNCCNMGNTTYGAYGAYGARTCN GAYTTYCCNTCNYTNYTNAARACNGCNGCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNCAYGTNMGNTTYAARAAYAGYAARCARMGNGTNAARGAYGCNAARGTNCAR GTNGARAARAARGCNMGNTTYATHCAYAARAAR---------AARTCNMGNCAR---ATH ---AAYAGYCCNACNGARMGNAGYACNATHYTNGCNGARAARCCNATHGAYAAYGTNTGG ATHMGNAARTTYTAYCCNCARCCNMGNTTYTCNATHGARGARGCNATHAAYMGNCAYCAR GCNTTYGCNCARCCNGCNATGYTNGAYAAYATGGAYGGNYTNGTNTAYYTNGAYATGCAR YTNGAYTTYAARACNAARAARCARACNAARTTYATGAARAAYATHMGNTCNACNYTNYTN YTNCCNTTYCCNTTYACNTGGGGNGCNCCNCCNTCNATHYTNGTNTTYTGYAARGARGAR GARCAYACNAAYYTNGCNYTNTCNYTNGGNGCNAARCAYGCNGGNTCNCCNGCNGARATH ATHAARATGGTNGARAAYGGNGTNYTNAAYCCNAARGAYTAYGARCAYGTNYTNGCNACN GCNGAYTGYGGNGCNGAYATHACNCCNGCNMGNTCNTAYTTYMGNGAYAARTTYCCNCAR MGNGCNAARGGNAAYYTNGGNACNGAYYTNATGGCNATGTGGACNYTNTTYTAYACNGGN TAYACNTAYGARTCNCARAAYATHACNGARGCNYTNGGNAARYTNCARGTNCCNYTNGGN CARYTNAARCARTCNACNAGYCARYTNGTNGCNAAYTTYGARGCNTAYATHGARTCNGTN TGYAARCAYMGNAGYATHGCNYTNGGNCCNTTYATHCARTCNATHAGYGTNGTNGCNCCN CCNTCNCCNGARCARTTYYTNGTNCARGTNGARGAYTAYGTNCCNGGNTAYAARAAYGAR GARATHGAYTCNGAYGAYGARGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNAARAAYGCNTCNCAYYTNGARGAYTTY TTYCAYCCNGGNAARACNGAYCAYMGNACNGARAARACNGAYTCNTTYTCNGARTTYAAR AARCARAARTCNAAYATHGARAGYTCNMGNCARAGYGTNTTYAARGARTTYCARCCNTTY AGYTTYTTYYTNACNAARGTNTCNGGNATHGARAARCARTTYAAYAAYACNGGNGCNATG AGYYTNAARGAYATHYTNTCNCCNGARATGGGNCARYTNAARTCNTCNTGYCAYTTYAAY TTYATGTTYGAYGTNCARTGGYTNATGAARCARTAYGCNCARGAYGAYMGNAARYTNCCN GTNYTNYTNGTNCAYGGNGAYCARGGNMGNGCNGARATGGAYYTNAARGAYGARGCNTCN CCNTAYCCNAAYATHTCNYTNTGYMGNGCNMGNYTNGAYATHCCNTAYGGNACNCAYCAY ACNAARATGATGYTNYTNYTNTAYACNACNGGNYTNMGNGTNGTNATHCAYACNGCNAAY YTNATHCCNAAYGAYTGGCAYCARAARACNCARGGNATHTGGATHAGYAAYATHTTYCCN CAYACN---ACNAAYCCNTCNGAYCCNGGNGAYTCNCCNACNMGNTTYAARGCNGAYYTN YTNCARTAYYTNGCNGCNTAYGTNTCNCCNAARATGACNGTNTGGGARMGNYTNATHAAR GARCAYGAYATGTCNTCNGCNAAYGTNCAYATHGTNGCNTCNGTNCCNGGNMGNCAYACN ATGAAYAGYAARCAYTAYTGGGGNCAYYTNAARYTNAARAARGTNYTNYTNGAYCARGGN CCNGARGARGGNATHGTNMGNAAYTGGCCNGTNGTNGGNCARTTYTCNAGYATHGGNTCN YTNGGNGCNAAYCARGAYGTNTGGYTNYTNAGYGARTTYGGNCARTCNYTNTCNCARTGY AARAARAGYATGTCNMGNTCNATHCCNGCNTCNAARYTNAAYYTNATHTTYCCNTCNATG AAYAAYATHMGNYTNAGYYTNGARGGNTAYAAYGGNGGNGGNTGYGTNCCNTAYAGYATH AARACNGCNTCNAARCARCCNTGGYTNACNCCNTTYTTYAGYCARTGGAARTCNGARGGN MGNGGNMGNTCNGGNGCNGTNCCNCAYATHAARTCNTAYACNMGNTGYTCNCCNGAYGGN TCNCARGCNGCNTGGTTYGTNGTNACNAGYGCNAAYYTNTCNAARGCNGCNTGGGGNTCN YTNGARAARAARGGNAGYCARYTNATGATHMGNTCNTAYGARATGGGNGTNYTNTTYYTN CCNGCNAGYTTYGGNTGYAARCAYTCNTTYAGYGTNAGYAGYCAYATHGAYCARGTNACN GAYCCNGAYMGNAARGTNTTYCCNYTNCCNTAYGAYYTNCCNCCNACNACNTAYATHMGN GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYGARGAYYTNTCNGAYGAYGARAGYYTNGCNGARGCNGCN AAYAARGCNGGNYTNAGYCARGARGARATHAAYTTYYTNYTNTCNMGNGTNAARGAYCCN GARGTNAARGAYMGNYTNAARAGYAAYACNGAYGARGCNATGGARYTNGGNGCNTTYGGN TCNCCNATGATHGTNYTNGAYGTNAAYGGNGARAARGARATGATHTTYGGNAGYGAYMGN TTYCCNATHYTNGCNCARATGYTNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TTYGGNTGYCAYCCNYTNACNMGNYTNGTNTTYGTN CCNGTNTTYYTNTGGYTNYTNATHGARAAYCAYACNGGNATHGAYYTNCCNTGGGCNYTN CAYMGNYTNTGYCCNGGNCARYTNATGGGNGGNCCNGCNAARCAYCAYGCNCAYCAYACN CARGGNCAYGGNCAYTAYCARCCNTTYTTYACNTAYYTNGAYAAYTGGYTNGAR------ CCNGCNAGYCCNTAYAAYCCNTAYATHACNACNTCNATGCCNGCNCAYTCNGTNGGNATG ACNACNAAYGGNGAYGCNAAYTCNCCNATHATHTCNCARGCNYTNCCNCAYACNATGATH CCNGCNACNCCNAARGCNGTNMGNGCNGAYAARTTYGARGCNACN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARATHTCNTGYCCNGTN TGYYTNGAYGAYYTNAARCARATHAARTCNAGYAARMGNMGNGTNATGTCNACNATHTGY GGNCAYATHTTYTGYGARGARTGYATHACNAAYGCNATHMGNTCNYTNMGNTCNTGYCCN TCNTGYMGNAARTCNYTNACNYTNAAYAARATHCAYCCNATHTTYYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------MGNGTNYTNAGYGARGCNAAR ATGGAYYTNTCNAAYATHAARGAYGAYTCNMGNCCNGCNTTYCCNMGNCCNCCNTGYTGY ATHGGNYTNTAYATHGAYGCNYTNGAYGCNMGNCCNGAYAARAAYACNACNGTNGGNTCN CARCAYGCNTTYATGATGAGYGTNATGGAYAARATGCARGAYTAYYTNMGNACNCAYGAY YTNTCNAARGTNAARGGNGCNYTNGARTCNMGNMGNGTNGCNGAYGGNGTNATHYTNGAR GGNTCNAARCAYAGYTGYATHGTNGCNYTNACNTTYGAYCAYYTNGAYGCNYTNGARGAY ATGTGGACNYTNAAYAARAARAAYMGNYTNTCNGTNYTNTTYCARGAYGTNYTNGTNGAY AARCARYTNYTNAARGCNACNAAYTGYGCNAARYTNACNYTNMGNGTNAARYTNTGGGAR GAYGARGTNAARGGNTGYMGNGARGAYYTNMGNTCNMGNCCNGAYACNMGNYTNAARYTN TCNTCNTCNGAYMGNGAYTTYTCNATGGTNMGNMGNGTNCARGARCAYCARAAYGTNATG CCNGARTGYGTNGCNAARGCNMGNGAYGCNGARAGYAARTTYGARCAYAAYYTNGGNGAR TTYATGYTNACNATHAARCARATHYTNCCNGARAAYACNCARGTNATHAARTCNATHAAR GARTTYATHACNAAYGTNAARATGGCNMGNGGNGTNAARAARATHCARTTYGAYAARATH GAYCAYTAYYTNCARTCNYTNGARTAYTTYMGNAARACNTTYCARGARATHGARMGNGAR ATHGTNCAYCCNYTNTGYCARATHCARGCNGTNTGYGARAAYGARAARCARMGNAAYYTN AARAARACNATHAARAARTCNTGYCARGARATGYTNGAYTAYYTNMGNCCNGARGTNGAY YTNGARAARGTNMGNCAYAARGARTGGGARGGNAARGTNYTNACNMGNGARCARGGNYTN TTYTAYGGNYTNATHAGYYTNATHCCNATGTGYGTNGAYMGNYTNACNACNATHGAYTAY AGYACNGAYGARTAYATHAAYGAYTTYCCNGARGTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GCNCARAGYGARGAYGARGARCCNYTNATHCAYCAYCCNTTYAARGTNAARGAY ACNTCNTCNAAYATHGTNATGAAYATHMGNAAYGCNAARCARYTNCCNGTNYTNACNCCN TCNGARAARCARGTNCARCARGCNTCNYTNMGNYTNGCNTAYCCNGTNTCNAGYGGNTCN CAYCAYMGNGCNAAYGARTCNGARTGGGTNCCNGTNMGNACNACNGCNGCNCCNACNTCN ACNGTNAAYAARGCNACNAAYTCN---YTNCCNTCNACNGTNTCNCARCCN------GAR CCNCCNAAR---------AGYATHTTYCCNAARGCNAGYGAYAARGTNGAYATHGGNACN ATHATHTCNGARMGNYTNCARGCNGTNMGNAARYTNCARGCNAAYCCNTAYGAYGTNCAR GCNYTNAGYACNATGCAYAARGCNCARGARAARGCNAGYCARTGGGCNCARTCNAARCAY YTNCCNGGNCARTTYATHGGNACNACNGGNGCNCARATHATGTCNCARCARGARATHATG GGNGAYAARMGNCAYCARGCNTGGGTNAARAAR------------------------TCN CAR------------------------------TTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CCNGGNATH AGYTAYGCNGGNACNGAYMGNCAYGGNAARTCNTCNGTNCARGGNYTNYTNGCNATHGCN TGGGTNGAYGARGTNGARACNGAYAARTCNYTNTTYYTNGAYTGGACNAAYMGNGARATG ATHTTYATHGCNGAYTTYGARATGAAYGTNTCNAARGCNATHTAYAGYAARGAYTTYMGN AARGARAGYTTYACNTGYCAYTCNGTNTGYACNGAYYTNGGNMGNTCNTCNATGACNATH GARGTNTGYYTNYTNGCNGCNAAYGARACNGARCCNGTNATHAGYGCNACNCAYMGNTCN GTNAAYGTNGAYCCNCAYAGYMGNAARGCNAGYCCNTGGCCNTCNTGGYTNTCNGAYAAR TTYAARAGYAARYTNTCNTAYGCNGCNMGNTCNCARAAYMGNCARTTYGGNMGNCCNCAR AAYAGYTTYATHCARAGYGTNATHGTNGTNCCNTCNGAYACNGAYGCNAAYGGNCAYTGY AAYTTYGCNAGYTAYGCNAARTTYGCNGAYGAYGCNYTNCAYACNGCNYTNMGNYTNMGN GGNAGYAAYTCNYTNACNMGNACNYTNTCNAGYGARGARAARGAYTTYTGYGGNAGYCCN TCNGCNGCNYTNAARGGNATHTCNCCNCARGCNGTNAARGGNGGNATHAARAAYTTYAAR ATHMGNTTYTTYCARGARTGYCAYGARGGNCARMGNYTNAAYGTNCAYATHTGGCARGAY GGNATHAARGAYACNGTNGTNTAYTCNTCNATHGARAARGARGAYGTNATHCARATHGTN ATGGARTTYTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AGYCARYTNATHATHGCNGGNCCNGAYACNGCNAAYAAR ACNTCNYTNGTNTTYCARGCNGCNGTNACNGTNGCNACNAGYGGNTAYAAYGTNGTNCAY ATHTGYACNCAYCCNATHTCNMGNYTNCCNACNCCNGTNCAYGGNATGCCNAAYCCNAAR CCNACNGTNATGAARAAYGTNGAYTTYYTNTAYTTYGARGAYTGYGCNGAYYTNATHGCN TAYTTYGCNGGNATHCAYATGAARAARAARYTNCCNACNTTYGTNATHGTNGARGAYATH YTNTCNTAYGCNTCNCARMGNCARGAYAARCCNATGGARAARTCNYTNGCNATGYTNYTN GCNGTNATHTCNAAYGCNTCNACNTGGACNGCNGCNCAYAAYGARACNGGNAARTGYCAY GTNYTNYTNACNGCNCCNACNMGNATHAARTCNATGCARAAYATHYTNAARCARTTYGAY TAYAARYTNGCNATHTAYGARGGNCCNACNAAYGAYAAYAGYYTNTCNAARATHTCNTGY AGYAARACNCARATHACNATGTCNGTNACNTTYCARMGNYTNAARGAYTGYYTNTTYYTN AAYGAY------------------------------------YTNATHCARATHAARACN GCNGAYGARAARGARGTNCARMGNMGNATHGAYTCNTTYATHMGNAAYAARMGNAAYGAY ATHAAYGARMGNAAYATHMGNGARTTYATHTCNCCNTTYGGNTCNGAYCCNGGNAAYAGY TGYGCNMGNGTNGARGCNGTNTAYGTNCAYMGNGARGGNATGAARAGYCAYATHAAYYTN AARAAYGTNGARAAYGTNTCNGGNCCNCARACNMGNYTNMGNCCNGAYACNAGYGARGAR ACNCCNTCNTGGATGAARCCNGCNGAYGTNCARMGNGCNGARGCNATHGARGARMGNYTN TCNAAYATGGARTCNCAYYTNGAYATGGGNAGYAAYGGNGGNGAYATHTAYMGNMGNATH AARTCNYTNGARGARMGNATHAGYTTYYTNGARGGNATHTCNCCNGARTAYTTYGCNCAY GGNYTNCCNCCNACNATGGARAARAARTCNACNTAYCCNAARCAYGAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGGCNACNAAYATHCAYTTY GARGCNMGNMGNMGNCARATGGTNYTNGAYAARGCNTGYAARGCNMGNAARGARATGGCN YTNGTNCARAGYTCNGAYGGNGGNGCNTCNTCNGTNCARAAYGGNGCNAAR---CCNGAR ACNATHATGTGYACNGAYCARGGNCARTTYTAYCARACNMGNCCNAGYATHCAYGTNTGG ACNGGNCCNGARMGNAAYMGNMGNACNTAYGAYCARAGYMGNGARGGNCCNATHYTNGGN ACNTCNAARMGNCARYTNCARMGNGARATGAAYTTYMGNGARAARTGYYTNAGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGCCNAAR TTYTAYGARGAYGTNGARGAYAARAGYAGYCAYAARAARATGGCNTGYGARGGNATHMGN GAYGAYYTNYTNGARTGYYTNYTNAARAGYGAYTGYTGYMGNMGNGAYAARAAYACNCCN MGNGARTGYATG---------AGYAARGTNGGNGAYCCNTCNGTNCCNGAYGARTGYCAY AARYTNMGNGTNGCNTTYYTNGARTGYMGNMGNTCNATGYTNGAYATGMGNACNMGNTTY MGNGGNMGNAARGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GAYGAYMGNTCNAARAARAAYGCNATHCARGCNAARATHAAYMGNGARAARAARAARGCN TAYATHAARAGYYTNGARGAYGARATHAARACNYTNAARAGYGAYAAYGCNAARYTNGCN GCNGARAAYACNMGNATGCARCARTCNACNACNGAYYTNCARGARGARGTNGARTAYYTN AARTCNGTNYTNGTNAAYTCNAGYGCNYTNTCNGAYYTNYTNAARAAYATHTCNAAYGTN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CARGAYACNGTNGGNGCNATHTGYGTNGAYCAYGARGGNAAYGTNGCNGCNGCN TCNTCNAGYGGNGGNATHTGGYTNAARCAYCCNGGNMGNYTNGGNCCNATHTCNATGTAY GGNGCNGGNTGYTGGGCNCARAAYAARACNTCN---GAYAARCCNGGNGTNGCNGTNYTN ACNTCNGGNTGYGGNGARCAYATGATGCARACNATHYTNGCNAARACNTGYGCNGAYGGN ATHMGNTCNTCNGARAAYYTNGCNCARTCNYTNTCNCARGTNTTYAARACNGAYTTYYTN GARTCNGARTTYYTNTCNTCNAARTCNGARAARATGGGNGGNGTNYTNGCNGTNAARTTY AAYGAYYTNTCNGAYTCNAARGAYGTNGARYTNTGYTGGATHCAYTCNACNGCNAGYTTY TGYTTYGCNTTYATGGGNGGNGAYCARAARGCNCCNAARGCNGTNATGTCNCAYYTNGAR GARCARTGYATHCCNGGNCAYTCNTTYTCNATGGGNGGNCAYYTNGTNTGYYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GGNAGYTCNACN AGYTAYGTNACNYTNATHTCNCARATH------GTNCCNTCN---------YTNCARMGN ACN---TCNTAYYTNGAYAARTAYMGNAAYGGNATGAARAAYTGGTGGCARGTNATHTAY ATHGGNGGNGCNGTNYTNGGNGGNTAYGTNTCNGCNYTNGCNTCNGGNACNYTNGGNAGY GTNGARGGNGTNCCNTGGMGNCARGGNTTYGGNGGNGGNYTNYTNATHATHTAYGGNTCN MGNYTNGCNGGNGGNTGYACNAGYGGNCAYGGNYTNTCNGGNATGGGNYTNYTNGCNYTN GTNTCNTTYGCNGTNGTNCCNGCNATGTTY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CARCARCARCARCARCARCARCAYTCNCCNAAYAGYYTNGCNGCNATHGGNTCNMGNAAY GTNYTNAGYGTNCARAGYCARAGYGGNCARCARAGYYTNGTNAGYATGCARAARMGNCCN TTYAGYTCNGCNGGNCCNATGCCNAAYTTYGCNTCNAGYTAYGGNTTYGGNGGNGCNGGN TCNATHGAYTCNCAYCCNACNATHGAYYTNTCNGAYTTYCCNACNYTNAGYAGYMGNTCN TCNGCNACNCCNAAYCCNYTNCCNTCNACNMGNAAYTAYGTNGGNATGGTNAGYAARCCN GCNCARGAYTCNGCNCCNGARTTYAAYATHTCNCARGARGARTTYCCNGCNYTNCCN--- ------------------------------TCNGAYTAYMGNCCNMGNGGNGGNMGNAGY AGYMGNGGNMGNGGNGGNCCNCCNMGN---GGNGGNGGNTTYMGNGGNMGNGGNAGYTAY ---YTNGAYMGNGAYAGYGGNMGNGGNGGNTTY---MGNGGNMGNGGNGGNTTYTCNMGN GGNMGNGGNGGNCCNCCNMGNAGYMGNGAYGGNYTNTCNCCNCCNMGN------YTNTCN MGNAGYTAYGAYAGYGGNGAYMGNGGNMGNGGNCCNCCNCCNAGYMGNMGN---GAYMGN TAYGAYGAYAGYTTYGAY------TCNMGNCCNYTNMGNATGAARGAYYTNTAYTCNTCN CCNCCNMGNGAYTCNGGNMGNTCNTTYGAYMGNCAYTCNCCNCCN------CCNMGNMGN GARMGNGAYTAYGCNCCN---MGNCAYAGYGAYCAYAGYTCNTCNMGNGGNGAYTAYYTN TCNCCNMGNAGYTAYTCNCCNCCNMGNGAYACNGGNTAYGGNTCNTCNTAYAARGAYTCN TAYAGYTCNGGNYTNMGNGARGARMGNMGNCCNATGMGNGAYTAYCCNCCNMGN------ ------------TCNAGYGAYTAY---GAYMGNMGNGAYTTYMGNGAYACNGCNMGN--- GAYTAY------AGYTCNMGNGAYTAYCCNTCN---------MGNAAYGGNGAYTTYMGN GAYTCNYTNGGNAGYMGNGAYTTYMGNGARCCNYTNMGNAGYGAYMGNTAYAGYGAYMGN GGNAGYAGYMGNGGNMGNGGNGGNMGNTCNMGNTTYGARGAYMGNGGNCCNCCN------ ------MGNGARTAYGGNGGNMGN------------------------------GGNMGN GGN---MGNGAYGAYMGNGGNMGNGGNTTYATGAAYGGNTCNMGNGGNCCNMGN---GGN AGYCCNMGNGGNMGNGGNMGNGAYTTY---GGNGGNAGYMGN------MGNTCNCCNAGY CCN------------------------GARMGNGCNGGN--------------------- ------------GGNAARMGNCCNMGNYTNGAYTCNGGNGAYTAYMGNMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AGYCCNGARAAYATGGCNGCNGCN CCNTAYTAYTAYACNGTNTCNCCNTCNTCNCARGGNACNGAYGARGAYATGATGTCNAAR ATGTCNACNGAYAAYCCNACN------AARTGGCCNYTNTCNAGYATHYTNAAYATGGAY GARYTNCCNGARCCNGCNGTNGGNGCNTTYTCNGCNCARMGNCCNAAYGCNYTNAARGTN GARGARAARGAYYTNCCNTTYGARGGNYTNATGAARMGNAGYATGATGGCNMGNYTNGAR CARAARCARAARCARGARTCNMGNGARAARGAR---------GAYAGYGGNGTNGAYATH TCNAAYGARGTNMGNAARGTNGGN------GCNAAYGARGAYGARAARGARAAYCAYGTN YTNAGYGCNTTYTCNAAY---AAYATGTCNYTNGARGARGARTAYGTNATHGTNGAYCCN CCNTTYGCNAGYGAYGAYGAYCCNMGNGAYGTNAARTCNTTYYTNGGNGTNATGTTYMGN GCNCCNCAYYTNTAYGAYAAYCCNGAYGTNMGNYTNAGYGTNGAYGAYTAYYTNAGYGAY GTNGGNGCNATGATGTCNMGNYTNGARGARGAYATGCCNGTNYTNGAYGARTTYTGYCAR TCNATHATHAAYTTYAAYAGYACNGARGAYGARGAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARTTYACNGAYGCNGARATH MGNGARGARYTNGCNCAYYTNGGNTAYCAYGAYGTNCCNCARGAYAARYTNGARGAYTTY AARAARGAYYTNATGMGNYTNATHTCNACNGARMGNAGYAARACNAAYTCNYTNAAYAGY AGYMGNACNACNGARCCNGARAARGARGTNAARGARTCNCAYCCNMGNCAYCARTAYTCN AGYGCNGGNTTYGTNGARGARGAYTTYACNAAYCAYGGNAAYCARTGGATH---GGNAGY CARTTYAAYGARGAYTGGCARTAYCARGGNGARAARGARAGYCARCCN------------ ------------------------------------MGNCCNMGNACNGCNCCNGARCAY CAYAGYCAYCCNMGNAARGGNATHYTNACNAGYGGNTAYTCNAGYTAYAARGCNCCNATH TCNTCNTCNACNMGNGAYATGGARMGNAAYCARAGYTGYCAYMGNGAYGAYGTNTCNGAR TCNGGNTCNGAYAGYMGNTGYATGAARMGNAARACNTCNMGNAARACNGCNAGYGGNTGY MGNCARGTNGAYGARTCNTTYACNGAYAGYGAYTCNGGNGTNTTYGARATHTAYGARMGN ATHAARACNYTNGCNATGMGNGARTGYGARTGYGGNAARTCNAARTCNAARTCNGGNGAY GTNGARCCNCCNTAYMGNATHAARGGN---AARAAYAARAAYCCNTCNGTNATHAARAAR YTNGCNCCNCCNCAYAAYMGNAAYYTNGTNMGNATGAAYATGTAYGAYMGNYTNAAYATG TAYAARGARATGTGGAARGCNCARCCNCCNATHGGNGARGAYGARMGNGTNGGNGTNMGN AARGCNACNCARGCNMGNYTNATGCAYTTYGAYGGNATHAARYTNAARCCNAARGTNTTY GTNCCNAAYYTNTAYGTNCCNCCNCAYGARAARAARMGNYTNGAYYTNMGNTGGAARGTN MGNMGNGCNTTYGARGCNTAYGARYTNCCNGARCAYGGNTAYTAYCAYGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ACNATH CAYGARTAYAARTGYCCNTCNACNYTNATHCAYMGNTTYTCNAAYYTNGTNATHYTNGAY AAYCAYATH---AARACNGAYTAYCAYYTNCCNGTNGAYAARATHATHATHTAYCCNYTN GTNGAYCCNCARATHAARCCN------GAYGARATHAARGAYCCN---------GCNYTN ACNYTNCARCARCCNYTNAARGARGCNAARGARATHATGAARATHMGNCAYAARAARATG AARAARCAYAARYTNAARAARYTNMGNAARMGNATGTAYTTYGTNTGGAARAARCARAAR ATGACNMGNAARGCNAARMGNGAYGGNGTNTAYTGGAARGARATHGARGARATHAARAAR GAYGGNGAYGAYTTYGARGCNGARGTNTTYGTNAARGARCARYTNGARMGNGCNMGNMGN GGNGGNTAYTTYATHAAYGTNTTYGAYTCNAAR---TGGCARGCNGCNAARACNGAYTGY GCNMGNCARGGNGCNAARYTNGCNAARATHACNGAYGGNTCNATGATGTCNTTYGTNAGY GCNYTNGAYTGYAAYMGNTGYTGGATHGGNYTNCAYGAYMGNGAYGARGAYGGNGTNTGG ACNTGGGTN---GAYAAYMGNCCNACNAAYTTYACNTTYTGGYTNCCNAGYCARCCNCAR AGYAAY---AAYGAYCARCAYTGYGTNGARATHATHCAR---TCNATGTGYTCNGGNTGG AAYGAYCARGTNTGYGARGCNGARMGNAAYTAYATHTGYCAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYATHATGGARGARTTYCCNYTNYTN GAYGCNMGNYTNTGYGARYTNGAYYTNAARCAYGCNTTYGTNATGGTNCARCCNCARGGN CAYAARATGGCNGARYTNATHTGGGARTGGYTNYTNGCNCAYCARMGNAARCAYGGNTTY TCNTGYYTNACNYTNGAYGAYACNAARACNMGNYTNTTYGCNAGYTGYACNGAYGAYACN ATHTAYGARTAYAAYATGAARTCNGAYGARGAYAARCCNATHGGNTGYTTYAARGGNCAY AARAAYTCNACNTTYTAYGTNAARACNGCNATHAGYCCN--------------------- ------------------------------------------------------------ ---------------------------TTYGARYTNYTNYTNAARTGYGARTGGATHCAY AAYTTYCARGTNACNGAYGTNTTYAARGAYGARGTNATHTCNAARYTNCCNGARAAYTGG TAYTTYTGYYTNGCNGARYTNAGYATHGARGAYYTNAAYGARGTNCCNTTYYTNGARGGN AARAGYMGNTCNAARTAYCCNGARTGGCCNACNTCNYTNCAYGAYTTYYTNAGYCARYTN GCNAGYTTYMGNAAYGARGGNTCNGARGAYTCNGARATHMGNCCNGTNGAYATHAGYGCN AAYATGGCNMGNGGNATGAAYTCNAARAARMGNCAYGARGTNACNMGNATGGCNTCNYTN GTNTAYGAYGTNGTNATGGARACNGAYTGYGAYATHGTNATHGAYATHGGNTCNGGNYTN GGNTAYYTNGAYCAYGTNYTNCAYCARACNTAYGGNYTNAARGTNYTNGGNATGGARACN GTNCARAGYCAYGCNTCNGCNGCNGARMGNMGNGCNGTNAARCARGGNATHACNTGYGAY GGNATHAARAGYYTNCARTGYCAYATHGCNGAYAAYGARGCNTCNTAYACNGARTTYGTN TCNGCNGTNCARACNGCNTAYCCNACNYTNCARTGYGAYTGY---GAYAARMGNYTNAAR GAYAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------ACNCAYTCNACNTTYGCNAARTTYCCNYTN AGYGARGARGGNAARGCNYTNTAYAARCARTTYACNYTNAARCAYGGNMGNCCNTTYATH ACNCCNTTYACNYTNMGNYTNGGNGCNCARGARACNMGNTGYMGNTGGMGNCAYCARACN AAYGCNGAYCAYGARTCNCAYATHAAYCAYGTNGCNTTYMGNGGNYTNYTNTCNTTYACN AAYGARGARGAYMGNGAYATHMGNCARAARGTNMGNCAYTGYAGYTTYGAYTCNATHCAY GGNTTYATHGAYTCNTTYTAYGGNAARYTNAGYGAYAAYCCNTCNACNGCNGARAARMGN TCNMGNYTNYTNTCNYTNTAYGAYAARTAYAARAARGAYTTYGAYGCNATHGARATHYTN ACNYTNTTYCARGTNATHYTNCARCCNGTNATHGARACNYTNYTNTAYYTNGAYMGNAAR CARTGGYTNCARGARCARGGNCAYMGNGTNGTNAARGTNGTNCCNGCNTTYGAYGARATG ATHTCNCCNMGNAAYYTNTGYYTNTTYGCNACNAAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNAGYGTNTCNTGGCCNGTNATHTTYGCNCCNYTNTTYATHTGY GAYGGNYTNAAYGCNTAYYTNTGYGTNATHATHTTYGTNMGNCARTAYMGNGARTAYGAR YTNAARCARGCNTGYYTNMGNYTNTCNAAYTCNYTNTCNGTNATHACNYTNATHTTYACN TTYAARYTNYTNYTNTGYCARAARYTNGCNAAYGGNGGNYTNACNTGYTCNGARGTNTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GTNATGYTNAAYGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARAAYYTNAARATGGGN GAYGGNATGTCNGCNTAYATGGTNTTYAARATHGTNACNAARACNACNAAYCCNGCNTTY MGNACNCCNGARAAYACNGTNYTNMGNMGNTTYAGYGAYTTYYTNGGNYTNCAYGCNAAR YTNGCNGARAARCAYGTNCCNYTNGGNATHATHGTNCCNCCNGCNCCNGARAARAGYGTN ATHGGNATGACNAARGTNAARATGTCNAARGARGAYTCNGGNAAYATHGAYTTYATHGAR MGNMGNAARGCNGCNYTNGARMGNTAYYTNATHMGNACNGCNGCNCAYCCNACNYTNGCN GCNGAYGCNGAYTTYATHGARTTYYTNGARAARGAYGGNGAYYTNCCNAARGCNACNAAY ACNTCNGCNYTNAGYGGNGCNGGNGTNATGMGNYTNTTYCAYAARGTNGGNGARTCNYTN GARAARATHACNYTNAARGTNGAYGARAGYGAYGARTGGTTYGARGARAARCAYCARCAR ATHGARGCNYTNGAYCARCARYTNMGNAARYTNCAYTCNAGYYTNGARATHYTNGCNTCN CAYMGNMGNGARYTNTCNGGNAGYACNGCNGTNTTYGCNAARAGYGCNGCNATGYTNGGN AAYGTNGARGARCAYACNGCNYTNTCNMGNGCNYTNTCNCARYTNGCNGARACNGARGAR AARATHGARATHGTNCAYAARGAYCARGCNGARGTNGAYTTYTAYACNATGTCNGARYTN ATGAARGAYTAYGTNGGNYTNATGGGNGCNGTNAARGAYGTNTTYCAYGARMGNATHAAR TGYTAYAARCARTGGAARGAYGCNGARACNACNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGNGCNACNYTNGGNCARCAYATGAARATHCAYYTNTCN CCNAARGARCCNGTNGTNTGYCCNAARGARGGNTGYGAYMGNACNTTYYTNTAYAARAAR AAYYTNMGNCARCAYATHMGNGCNTTYCAYGARGGNAARCARGTNTTYGTNAARMGNGAY AARGARGGNAAR---MGNGCNGARGGNAARAARTGYMGNGGNTCNAARAGYAAYAGYGCN GCNGCNMGNYTNTGYGGNYTNCARGAYMGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARTCNGGNATHACNGCNAAR ATHGCNMGNTGGTGGMGNCARAARMGNGCNGAYGGNTTYGAYCAYCARATHCCNAARTGY AGYCCNGAYTCNATGYTNYTNCAYATHTCNMGNYTNCCNGARTGYTAYAGYTTYYTNCAR AAYGARMGNAARMGNYTN---YTNAGYYTNATGGARTTYCAYTCNGARAGYGCNGAYYTN TTYGCNTCNYTNGCNAGYYTNGAYGAYTTYATHGGNAAYTTYTCNTCNGCNYTNAAYTTY GTNACNCARGCNATHGARYTNYTNCCNGAYTCNGCNGAYCAYCARTGGYTNMGNGARAAR ATHTCNMGNCARTGYGARATGYTNMGNMGNCARACNGAYTCNAARGARYTNATHGARAAR TCNAGYYTNMGNTTYCCNACNGCNATHGARGTNCCNMGNGARTCNGGNMGNACNYTNACN GTNYTNGAYTTYMGNGARAARTAYYTNAARCCNGGNAARCCNGTNATHATHACNGAYGTN GTNTCNGGNYTNACNTCNGAYCCNTTYGAYTTYTCNYTNGTNGTNAARCAYGCNGGNAGY ATHAAYATHACNACNAARGARGCNGTNAGYAAYTCNGTNACNTGGGCNAARYTNGARCCN AARMGNCARATGACNGTNTCNGARYTNATHGAYTGYGTNCARACNGGNTCNGTNAAYGAY GTNYTNTTYGAYTGGAGYYTNCCNYTNCAYTGYCCNAGYYTNGCNAGYYTNATHTCNYTN CCNTCNTAYTTYACNGGNAAYATHYTNYTNCARACNGCNCCNGGNTCNYTNTAYMGNCAY AGYTGGCCNAGYYTNTTYATHGCNCCNAARGGNGCNATHACNCARYTNCAYGTNGAYGCN TTYCAYTCNCAYTTYTGGATGGCNYTNTTYCARGGNAARAARMGNTGGACNTTYTTYGAY CARMGNGAYACNGCNYTNYTNTAYCCNMGNTTYTTYCARTCNATGGAYCCNGTNTTYGAR GTNGAYYTNTGYGAYCCNGAYATGGARAARTTYCCNYTNYTNGCNYTNACNMGNCCNCAR CARTGYGTNYTNTGYCARGGNGARYTNYTNTTYGTNCCNGCNGGNAGYCCNCAYTAYGTN GARAAYMGNAGYCCNACNYTNGCNATHTCNTCNAAYTAYGTNGAYCAYACNAAYYTNCAY AARGTNTGYGARGARYTNAARATHAAYGGNTGGCARGAYCARMGNGCNAARGAYYTNYTN GCNCARYTNCARGAYCCNGCNTTYYTNAGYMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AARMGNAARAGYYTNCARGARGARTCNTAYGARTTY ATGMGNGGNGTNATGGAYGARTGYACNCAYYTNGCNAAYTTYTCNGTNCCNGTNGAYCCN GARYTNGTNATHATHGTNTCNGCNACNCARGAYGCNTAYATHCCNMGNGAYGGNGTNGTN CCNYTNGAYAARYTNTGGCCNGGNTCNGARATHMGNACNGTNGAYCARGGNCAYGTNGGN GCNGTNYTNYTNCAYCARGAYGTNTTYMGNCARGCNGTNATHGAYGCNTTYGAYAARCAR ATHAARAARTAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGAAYMGNGGNYTNAARACNCARYTNYTNMGNGCNTCNATGAGYCARAAY GTNMGNGARAGYGCNTTYTGYAARTAYAGYCAYMGNGAYTGYACNCARAAYTGYYTNGAR GGNTAYACNTAYTGYATHMGNCAYATHYTNGARGAYAARCARGCNCCNTAYMGNCARTGY GCNTAYATHACNAARGCNGGNMGNAARTGYCCNGCNGCNGCNCCNAARYTNGARAARAAR GARGGNTAYTGYGCNTTYCAYACNAARAARGCNYTNATGACNMGNCARMGNATGGCNMGN AARMGNMGNCCNMGNGARACNCCNGARAGYYTNYTNGARGAYYTNGTNGTNACNACNTCN TCNATGGAYTCNCARCAYAGYATHGARCAYMGNMGNGGNAARATGCAYAGYGAYAGYATH GCNACNMGNGCNYTNGARTAYGCNAGYTCNAGYGAYTCNGARACNGARCCNYTNYTNGTN GARCAYGCNTGGMGNGAYTCNGGNGAYAGYGAYGCNGARAGYATHGAYAGYGAYCARGAR GAYGTNYTNAARCAYGCNGGNGTNTAYACNACNGARGARGTNGCNCARATHYTNMGNGAY AARYTNATHMGNYTNCARGCNYTNTAYATHGAYCARTTYAARMGNYTNAARCAYATHYTN YTNTCNAARMGNMGNAARTAYYTNYTNACNCARAARATGGARAARGARYTNTAYGGNAGY ATHAARMGNTAYAARGARGAYCCNCARATGMGNGARAARTAYGARAARYTNTGYGCNATG AARMGNTAYCAYAARAARTTYGGNATGGARGCNYTNATGCARCAYAARTCNACNCARMGN MGNATHAARGTNACNGARGGNATGAGYCAYAARATHCCNACNCCNGTNAARTGYATHTTY GTNGAYGARGGNYTNMGNTGYAGYCARGCNGTNGTNCCNYTNAGYAARTTYTGYCARAAR CAYATHYTNCAYGAYCARAAYCARGTNYTNTAYMGNCCNTGYCCNTTYGCNGAYAGYCAR TGYGGNMGNCCNGTNCCNACNYTNYTNGGNAGYCARTTYTGYTCNYTNCAYCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARGCNAAR ACNGAYAGYATHGGNAAYTAYCARACNTTYATHYTNCAYGAYGARGAYCAYACNYTNGGN AAYGCNATGAARTAYATHYTNAAYAARAAYCCNGARGCNACNTTYGTNGGNTAYAGYATH ACNCAYCCNTCNGARAGYAARATHAAYYTNMGNGTNCARACNACNGGNAAYTCNTCNGCN CARGTNYTNAARCARGGNTTYAARGAYYTNMGNCARYTNTAYGAYCAYATGYTNACNACN TTYGARTCNTCNACNAARTAYTAYAARGARAAYCAYATGGAYGTN---TGYGAYGARAAY CARTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARCAYGAYMGNMGNACNAARCAYCARTCNAAR------GTNGAYYTN TCNACNGAYTCNGCNGCNGAYGAYYTNTCNTTYTTYGARTTYGARCCNTGYGARGAYGAR ACNGCNGCNACNGCNTTYCCNYTNGCNATGTGGGAYYTNGARCAYTGYGAYCCNAARAAR TGYTCNGGNAARAARYTNAGYCAYYTNGGNYTNGTNAARACNYTNMGNYTNAAYAAYMGN TTYGGNGGNYTNATHYTNTCNCCNGTNGGNACNAARTGYGTNGCNCCNGAYGAYMGNACN ATHGTNGARGARAAYGGNGTNGCNGTNATHGAYTGYAGYTGGGCNAARYTNCARGAYACN CCNTTYGCNMGNATGAARGGNGAYCARCCNMGNYTNYTNCCNTAYYTNATHGCNGCNAAY CCNATHAAYTAYGGNMGNCCNTGYAARYTNTCNTGYGTNGARGCNTTYGCNGCNACNYTN TTYATHACNGGNTTYTCNAARGARGCNGARYTNYTNYTNGGNAARTTYAARTGGGGNTCN TCNTTYATHTCNYTNAAYAARGARYTNYTNGAYGCNTAYAGYAARTGYCAYACNAGYCAR GAYGTNGTNTCNGARCARGARAARATHYTNGCNMGNTTYCARGARGAYAGYMGNCARGAY AARYTNACNGAYTGGYTNTCNATHGAYCCNGAYGTNGAYGTNTGYAAYCCNAAYMGNCCN ------YTNTAYCCNCCNTCN------------GAYTCNTCNACNGARAGYTCNGAYGAR GAYACNGAYGARGTNGARAGYGAYAGYGAYGAY---------------------GARGGN GARAARATHGGNATGCARTGYGCNGCN------AARCAYCCNGARYTNTTYTTYGARATG ACNGCNGAYATGACNAAYCCNGAYAGYACNAARGTNYTNAAYGTNYTNTGYGARCAYCAR TCNGCNGTNGCNGAYATHATHYTNTGYGGNYTNAAYAARATGGGNGAYTGYTTYCCNGAR GCNAARCCNGTNATG------AARYTNATHACNTCNAARGAYCARTGGAARAARGCNYTN AARYTNGTNTGYAARAAYAARGARATHYTNAARGAYACNTGYATGGARGAYAAYATGGCN CCN---TTYATGACNTGYTAYATGGGNCARYTNACNAARYTNGARAAR------TCNGGN YTNAGYGGNGTNTCNAAYCCNAARGAYATHGTNTGYAARGTNATHCAYTCNGARGARAAY TGYYTNGTNGCNAAYMGNGGNTCNTGYAGYAAYAARTAYATHCARGTNYTNAARGAYATG YTNGARGCNATHTTYCCNGTNGARGAYTGYACNATHCARAGYAGYGGNAARACNGAYYTN GCNAAYTCNYTNCAYAGYATHYTNGTNCAYGGNGARCCNGCNYTNAARTTYAARCCNTAY GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARMGNAARYTNAARATHCAR AGYMGNAARTCNTAYAARACNGARCARGTNYTNTCNYTNCARGTNTAYAARYTNCARCAR GARCARAARACNYTNTCNGAYGARAAYGARAARGCNGTNGAYGARMGNGAYGCNYTNAAR TCNCARYTNGARGARGCNCARTGYGARGTNTCNMGNYTNMGNAGYCARYTNGARYTNAAR TCNCARTCN------------GARGGNCAYGARTCNCCNAAYTCNAAYGARGARYTNGCN ATGAARAAYAARGARGTNATHAAYYTNCAYACNCARGTNCARTCNTAYCARGTNGAYGTN GARAARAARAAYAARGARYTNGGNGARAARGCNAARGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GCNGTNATHYTNAAYYTNGGNTGYYTNATHTTYATGYTNCARTGGCARCCNGTNYTN GGNTCNYTNACNCCNTAYTTYGTNATHATGGGNATHTGGGGNATHAGYGAYGGNTTYTGG AAYACNCARGTNAAYAGYYTNGTNGGNATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARAARCCNGGNTAYGCNCAYATHAARTCNGAR TAYYTNYTNYTNGAYTAYAARCCNAARYTNCARACNGARTAYYTNAGYMGNGARGTNAAR GARAARYTN------ACNGCNTCNAARGARGARTGYCARACNCARGARGARGARGTNACN ---------------------------GARCCNCCNAAYAARAARGCNAARYTNAARGGN MGNAAYAARCAYMGNCCNMGNAAYGARMGNATHGARCARAARGAYAARYTNTGYCCNTCN ATHAARGARGGNMGNGARTGYAARTAYGGNACNGGNTGYAARTTYAAYCAYGAYGTNAAR GAYTTYYTNGARAARAARMGNCCNGAYATHCARGAYAARTGYCCNATHTTYGARACNYTN GGNTTYTGYMGNTCNGGNGTNACNTGYMGNTTYGCNAGYAGYCAYYTNGGNGARAAYAAY GARAAYYTNGTNAAYACNGARYTNTAYCARAARATGAARGARAARCCNMGNTGYYTNAAY AAYYTNAGYGAYAAYGCNMGNCARAARYTNTGGAARMGNAARTAYGAYTTYAGYMGNTCN ATGAARTCNYTNAARGAYGTNCARAAYTCNTTY---------AAYACNCCNAAYAGYAAR AAYGAYTGYGAR------------------------------------TGYAARGCNGAR GCNGCNAAYACNATGGAYTCNYTNGGNGAYAARGTNAAYCCNGAYAARGARGAYTTYTCN CCNYTNAARAAYGTNGARACNGTNAAYAAYAAYAGY------------------------ ---AAYYTNCARATHAAYGAYCCNAAYGTNGGNACNAGYAAYGAYYTNGARAAYGAYGCN ATGGGNTCNACNGCNAAYATHGAYAGYTCNCCNATHMGNYTNACNTCNMGNGARGTNAAR AARATHGAYTTYCAYAAYAARYTNTAYYTNGCNCCNYTNACNACNGTNGGNAAYYTNCCN TTYMGNMGNATHTGYAARAAYTAYGGNGCNGARATHACNTGYGGNGARATGGCNYTNGCN TCNCARYTNYTNAARGCNAARGCNTCNGARTGGTCNYTNATHAARMGNCAYCCNTGYGAR GAYATHTTYGGNGTNCARGTNTGYGGNGCNTAYCCNGAYATGATGACNAARTGYGCNCAR GTNYTNACNGARACNACNGAYATHGAYTTYATHGAYATHAAYTGYGGNTGYCCNATHGAY YTNATHTTYAARAARGGNAGYGGNAGYGCNYTNATGGGNAARGCNACNAARYTNGARCAR ATHTGYMGNAGYATGATHGGNGTNATGGGNGARAARCCNYTNACNGTNAARYTNMGNACN GGNGTNTTYGAYCAYAARAAYGTNGCNCAYAAYATHATHCCNMGNYTNMGNGAYGCNGGN GTNTCNYTNGTNACNATHCAYGGNMGNTCNMGNGARCARMGNTAYACNAARYTNGCNGAY TGGCARTAYATHGAYGARTGYGCNMGNYTNGGNCARCCNATGCCNGTNTAYGGNAAYGGN GAYATHYTNTCNTAYGARGAYGCNAAYYTNCAYATGGARMGNAAYGGNGTNTCNGGNGTN ATGYTNGCNMGNGGNGCNYTNATHAARCCNTGGATHTTYACNGARATHAARGARCARMGN CAYTGGGAYATHTCNTCNTCNGARMGNYTNGAYATHYTNMGNTCNTTYGCNAAYTAYGGN YTNGARCAYTGGGGNTCNGAYCAYCARGGNGTNGARACNACNMGNMGNTTYYTNYTNGAR TGGYTNTCNTTYYTNCAYMGNTAYATHCCNGTNGGNGTNYTNGARCARGTNCCNCARAAR ATHAAYGARMGNCCNCCNTAYTAYATHGGNMGNAAYGAYYTNGARACNYTNATGGCNAGY GCNAAYTGYGCNGAYTGGGTNAARATHAGYGARATGYTNYTNGGNCCNGTNCCNCARAGY TTYCARTTYYTNCCNAARCAYAARGCNAAYGCNTAYCAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNTTYGTNAAYYTNAARAGYCCNYTNAAYGTNGTNYTN AARMGNGARATHGAYGCNGGNMGNATHAARAARATHGAYAGYGGNMGNTTYACNATHTCN AGYGCNCARAARGARGARYTNGARAAYGAYGCNATHAARYTNGAYGCNAAYAARAARACN GAYTCNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GAYGTNGGNAAYGTN GAYMGNTTYGTNATHYTNGARCARGARATGGARGARYTNMGNTGYMGNYTNAGYGARAAR GAYGGNATHGTNYTNGAYYTNCARMGNTCNAAYGCNTCNYTNYTNGARYTNYTNGAR--- ---------AARAARGCNGAYGGNGAYAAYAGYGTNGCNACNCAYAARYTNGARGCNGAR YTNMGNAAYYTNMGNGGNGARMGNGARCAYATGGTNGCNGTNGTNAGYGARAARTCNMGN GARAAYTCNTCNYTNAARTCNGARATHCAYMGNYTNATGGAYYTNGTNTCNGCNGGNCAR ACNGCNYTNCARAARGCNCARCARGAYAAYYTNAAYYTNGARCARMGNCARAAYTCNCCN CCNMGNGAY---GARGARGAYGARGAYGARATGAARMGNGARGCNYTNAAYAAYATGGCN MGNYTNGTNMGNGAYMGNGAYACNGARATHGARGCNYTNACNCARAARAAYAAYACNYTN YTNGCNGTNYTNCARGAR---TCNTCNGARTCNCARGCNGCNGARCAYYTNGTNCCNYTN YTNAARGARAARGARGCNYTNAAYCARCARATGACNATHATGATGTCNGARMGNGARCAR YTNATHGCNGTNGTNCARCARAARCAYTCNGARTCNYTNGCNTTYCAYACNGARGTNCAR MGNYTNACNGCNYTNYTNGTNGARACNCARGAYTCNGCNGARAARGTNAARGCNGARTAY GCNACNYTNATHCCNTCNTTYGARGGNAARACNCARGCNYTNATHACNACNCARCARGAR YTNGTNGARTGYAARCARAARYTNACNGARATGGARATHMGNCAYGGNGARYTNYTNCAR MGNTCNAAYAGYCARCARAAYGTNCCNGAYTCNGCN------------GARGTN------ ------------------GARAARTAYAARMGNYTNGARTCNGAYTAYAARTCNATGGTN ATGGARMGNGAYGGNCARATHCAYTCNYTNTCNCARAARATHAARACNTTYGARGARGTN GCNGCNTCNAARGARAGYGARTGYYTNCAYYTNMGNAARCARYTNGAYAAYTCNAARTTY CARYTNACNGGNYTNATGGCNGARATHGCNGARGCNAARTCNGARMGNGARYTNGTNCAR CARAARAGYAAYACNCARAAYGARGARTCNTCNAGYYTNMGNCAYAGYYTNAGYCARATG ACNYTNGCNATGAARGAYMGNGAYGTNGARATHATGTCNYTNAARGAYCARATHTCNACN YTNAAYTCNGTNYTNCARAAYCARAARGGNGARAARGAYCARGTNGCNYTNYTNATHMGN GARCAYGARTCNGCNGTNGCNGCNAGYMGNCARYTNCARCARGARMGNGAYTAYAAYGCN ATGGTNGCNGARCARMGNCARCARGARTGYGAYGCNGCNAARACNGARYTNTCNGCNATG AARGAYAARGTNTTYAARCARGGNMGNGARYTNGARMGNYTNMGNAGYCAYYTNATHGAR ATHGARGARGGNTAYACNAARGARGCNYTNGARGCNGARGARMGNGARAARGAYYTNMGN AAYAARYTNGCNGTNGCNGARGARCARYTNYTNACNTCNTCNTCNCAYGTNCARYTNGCN AGYCARGARTCNCAYMGNCARATHGARAGYYTNCARGARCARYTNCAYCAYYTNGCNAGY CARMGNGAYTCNGCNTAYATGCARGTNGCNACNACNCARGAYCARTGYGARCARTAYGCN GCNTCNYTNAGYAAYYTNCARYTNGTNYTNGARCAYTTYCARAARGARAARGAYTCNGCN ATHGCNATGGARACNGARAARTAYCARGAYCARGCNAARTCNYTNTCNTCNAARGTNAAR GARYTNGARACNGARYTNGARGCNACNMGNAGYGAYYTNACNGARGCNYTNGAYGGNYTN GARGCNGCNTCNMGNYTNAGYGARCARYTNGAYMGNAARGARGARGCNATGATGGCNYTN AARGARGARGTNCARYTNMGNGARGAYGCNYTNAARACNGCNGARGARGARATHGCNAAR YTNAAYTCNAGYACNGARGCNAARGTNGAYAARACNYTNATGCAYAAYATGGTNYTNACN TGGYTNACNTCNCCNGARAARAARMGNCAYGARATHGTNCARYTNATHGGNCAYATHYTN GAYTTYAGYCCNGARGAYTTYYTNAARATHGAYTCNGCNCAYAGYCARGARAGYYTNTGG ATHGGNTTYTTYAARCARAARACNGAYTCNACNCCNAAYAARCCNAGYGGN------AAY CARTCNTTYTCNCARYTNTTYGTNAARTTYYTNGARAARGARTCNTCNCCNCCNCCNACN CCNGTNAARYTNCCNGTNGARGCNATGGCNGCNGARGCNCARYTNMGNCAYAARACNACN TTYAAYCCNTTYACNGCNCCNMGNCAYGTNACNCAYGGNAAYGARACNYTNGGNATHTCN ACNGGNTCNTCNTCNCAYYTNYTNATGCCNCARGAYACNCCNCAYCCNTCNCCNYTNTTY GCNCCNGTNACNTCNGTNTCNAAYGCNGGNGARAGYGCNATHYTNAARGAYGTNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AAYACNTGGGCNCARGARCARGTNATGATHGARATHGARAARYTN ATHMGNGGNTGYTGGGCNCARMGNCCNTCNTAYMGNYTNAAYATHYTNMGNGTNAARAAR AAYYTNCARGCNYTNMGNTCNCARTCNGARCARATHATGATGGARAARMGNGARAARYTN ACNGGNAARATHATGGAYGGNAGYACNACNACNAAYAGYGTNGTNACNACNTCNAGYAAY ATGYTNTTYAAYYTNGARGAYTGGAARCARGGNATGGAYYTNYTNTGYGARGAYYTNAAY MGNAARYTNGTNTTYMGNAAYCAYTTYGGNTGYYTNTCNMGNTTYTCNCCNMGNATHGCN AGYTGYATHYTNATHMGNACNCARATGTTYAARAARGCNGTNATGGAYGCNGGNATGGCN ACNCAYAARACNYTNCAYGAYATHACNTGYAAYTAYGCNGARAAYATHGTNAAYTGYYTN GARAGYCCNYTNGCNAARGCNTGYCCNATHYTNGTNGTNGAYACNATGGTNACNGCNYTN CAYMGNTTYYTNCCNCCNGCNTGYGCNCCNGTNCCNGCNATHAAYCCNMGNGTNGGNGAR GCNAARAAYGCNCAYGAYACN------------GTNYTNGARACNGTNATHYTNGARGGN GGNGGNGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MGNAARTTY MGNGGNATGGTNGAYGARAARAARAARGCNGARYTNGAYYTNMGNAARGTNYTNATHMGN YTNAAYCARATGAAYYTNGTNATGAARTCNCAYGGNATHGAYTCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYGARGARATGYTNGARGARGCNAARYTNYTNMGNCAY CAYAARGGNMGNYTNGARGCNMGNATGMGNGTNYTNGARGAYCAYAAYACNCARYTNGAR TCNCARYTNGCNMGNYTNMGNCARYTNYTNGARCARGCNCCNGGNGAYMGNAGYTTYATH TCNYTNGAYTCNTCNTCNMGNACNACNCCNATGACNACNCCNTCNTCNTCNCARAGYTCN TTYCARTTYGGNCCNAGYMGNTAYMGNATGGCNCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AGYMGNATHAAYMGN GCNGTNGAYTAYYTNMGNYTNTGGAARAAYGAYMGNAARTCNTGGAARTTYAAYAARGGN TTYCARTCNYTNYTNYTNAARGCNATHTAYAAYCCNGTNATHATHGAYGARGAYGAYTTY GARACNTCNYTNYTNTAYTTYGARGAYTCNCARGGNGGNGCNMGNGARAARYTNMGNACN GAYGCNATGGCNYTNATHAARGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGTCNGCN CCN---AGYGARAAYAARTAYYTNCCNTGYGAYGAYTTYATGAARTTYCARGAYGCNYTN MGNAAYYTNMGNGTNATHGAYGAYMGNATHATHCAYGCNYTNAAYMGNAAYYTNCCNACN CARTCNTTYCARGAYAARGTNGAYATHACNACNAAYTGYAARCAYGTNTAYGAYGAYATH CARACNTCNTAYAGYCAYMGNGARAARTCNATHYTNCAYTGYATHMGNYTNGTNAGYGAY GAYGTNAARAARYTNAAYGARAARAARCARCARAAYCCNGAYGAYYTNAGYGTNATHAAR TCNYTNMGNATGGARCARACNAARYTNMGNYTNATGCARCARGARYTNAAYGTNGARGAR GTNGTNAARGAYMGNACNYTNAARGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CCNTCNTAYCCNAARTGGCCNGAYACN TTYCARATHGAYTTYGCNGARGTNYTNTAYYTNCCNGTNGARGGNTAYCAYAAY------ ------------ACNACNGGNATHTAYTCNTAYGAYTAYCCNTCNAARMGNTAYMGNATH GAYMGNAARGAYGGNAARACNGAYMGNTAYTGY---GGNYTNAAYGGNTCNAARATHTTY TCNCAYACNCCNTGYTCNCARATHGTNAAY---GAYGGNGARMGNTAYATHTAYTAYCCN GARAARAAYNNNTGYTGYTAYTGYTGYTCNGARGARCAYGGNTGYGGNATHYTNAARCCN GAYTGGATG---AAYGGNGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNCCNGARGGNAGYMGNAAYGARGAYGARGAYGARGARGAY GGNCARGARGAYGAR------------------GGNMGNGGNGGNGARGGNGARGARATH GARTCNMGNGCNAGYGGNGARAGYGTNGTNTTYGAYGAYCARGTN---GARGAYATHCCN ATHGTNTCNGTNCAYATHGGNCCNGGNGAYGAYGTNGAYATHGARGGNAGYTCNGTNMGN TCNGCNTCNCCNAARAARGTNMGNTTYGARGARAGYGTNACNAARACNGCNTAYATHMGN CCNCCNTCNCAYGAYTCNTCNACNTGGACNGGNCARCCNGAYTAYGAYMGNTTYYTNTTY GTNMGNATHTTYTGYCCNGAYGGNYTNGARGARYTNGGNACNGGNATHAARTGYTCNYTN TCNTAYGAYGGNAAYATGYTNAARACNCCNATGYTNGAYGARATHGARGAYGARACNTCN GARGGNAAY------GAYGARYTNGAYGARMGNCCNACNCARMGNCCNCARGCNGCNAAR AARTCNGAYGARMGNTCNAAYCCNGAYGCNTCNCARGAYACNGARTCNACNAARACNAAR TCNAARAARTAYTTYGARYTNGARATHCCNYTNCCNGAYGARGTNGTNGARGGNATHYTN YTNATGGGNGARAARCCNCCNCCNGARCCNGARAAYYTNMGNATHGCNGTNCAYCARGGN CARTTYGARGARATHATHGCNATGGCNACNATHGAYTTYCARGAYATHAARGCNYTNAGY YTNGARACNATHTGGYTNCCNGCNCCNAGYGGNGAYGARGGNGTNGCNGAYGTNAARTCN MGNTCNAAYTCNYTNAGYGGNGCNTCNAGYGTNGGNGGNGARTCNYTNTCNGAYTCNATG GAYATHCCNATHATGYTNGAYGAYGAYCARCAYGCN---GGNGGNGGNYTNGTNTCNTCN ACNCCNMGNGAYGAYYTNYTNAARTCNAARGAYCCNYTNCCNTTYCCNYTNTAYCCNYTN CAYGGNGGNAARACNGAYTCNYTNCAYGTNCCNTGYGGNAAYGTNCCNYTNTTYYTNTAY TGGGGNAARMGNCCNMGNCCNYTNACNTTYGAYMGNCARTGYGGNACNYTNGGNATHTAY GAYATHGTNTAYGAYATHACNGGNTAYGAYATGACNACNACNACNAARGARGAYYTNCAY AARGARATGGTNGAYGARGCNYTNTCNGTNGCNGCNTTYACNCCNGAYCCNAAY------ ------------------GARGARACNGTNYTNAARTCNGARTAYGAYAARYTNGTNGAY MGNCAYCARGARGARATGATHTAYYTNCARGARGARTAYGARAARMGNYTNCARGARYTN GTNCARAAYYTNCARACNATGCARGCNGARAAYGARCARYTNCCNCARYTNATHTCNCAR CARTCNTCNCARCCNMGNCCNYTNTCNCARGCNTCNMGNGTNAGYTCNACNCCNGGNGCN ATHACNCCNATGACNGCNAARMGNTCNGARMGNTCNGAYCCNTCNTTYTAYGARAGYATH ---YTNCCNCARACNGGNCAYAGYATGMGNACNATHAGYMGNGAYAARGCN---AGYACN GARGTNGARMGNGARAARAGYATHATGTCNCARAGYACNACNAGYAAYMGNYTNAARCCN YTNCCNTCNMGNAAYCARAARCCNTCNAARAAYTTYMGNATHGGNAARCCNYTNCCNAAR TGGGGNGARACNYTNCCNCARGAYTTYTTYGAYMGNYTNMGNYTNTGGGARGARGARAAR AARCARCAYAARCARGARYTNAAYGARAARACNYTNAARGAYATHAARGAYAAYYTNGAR AARAARYTNGCNGGNCARCAYAARYTNAGYAARMGNGARGARYTNATHTAYGAYGCNYTN AARGAYGTNAGYYTNCCNGCNYTNTTYATGCCNTAYAARACNGGNAAYATHTTYAAYCCN MGNGCNCAYCAYTAYTTYCAYCCNACNGGNTCNTCNGAYGTNMGNYTNACNCARCCNCCN TCNGTNTTYACNYTNCCNCCNYTNCCNAAYAGYAARYTNTCNGTNGTNAAYYTNTTYGAR YTNAGYAARAAYTTYMGNAAYMGNGGNCCNGCNTGGYTNGTNGARMGNTAYATHCARCAR CARCARCCNTCNCAYGARGAYTAYCCNCARACNCCNGCNCCNACNTCNGCNGTNCCNCAR GTNACNACNACNTCNGGNCARAGYCCNATHAAYGAYMGNATGACNTCNCCNAAYAGYCAR MGNAGYATHCARCCNGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------MGNAARACNAARAAYAGYAARMGNAARGGNAARGGNAARCCN AARAARMGNMGNGARTCNYTNTCNGAYGAYGCNTCNTCNCCNMGNMGNMGNCARCCN--- CARGCNGCNCARCCNCCNCCNTTYCARAGYGGNGTNCCNTAYGGNGCNTAYCCNCCN--- CCNGGNGGNCARTTYGTNCCNGTNGTNGCNGGN---CARCCNCARTTYCARCCNGTNCCN ATGGTNCCNCCNAAYTAYCCNCCNCCNCARTAYCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNGGNTAYMGNAARATHTTYACNGCNGGNMGN GTNATHCCNGAYAAYAAYACNTAYAAYCARTTYGCNAGYGCNATHAARGARYTNGARAAR GARGGNGARGTNATHTGYGTNCAYTGYACNCAYGGNYTNAAYMGNTCNGGNTAYYTNATH TGYMGNTAYATGATHGARTTYYTNAAYATGGARCCNCARAARGCNATHAARYTNTTYGAR GAYGCNMGNGGNTAYAARATGGARMGNCCNAAYTAYATHGAYGAYYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARGGNATGAARMGNGAYGCNAARYTNTCNTAYYTNAARAAYTGGACNGAY ATHACNACNCAYYTNCAYGARCCNAGYATHTCNYTNYTNYTNCAYYTNCCNGTNYTNYTN GGNTAYTCNGARCCNTCNAAYMGNAARYTNATHGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARGARGARAGYTCNATHATGGAR AARAARGTNCCNGCNMGN------CARTCNCCNAGYCARTGYMGNAAY---GGNGTNACN GGNGARAARAARTCNGAYTTYACNCARAGYAARTAYGGNMGNTTYMGN------MGNCCN GTNTCNAAYGGNGGNACNAARACNCCNGAYGTNCARTCNCCNMGNCCNATHCCNYTNCAR AARTGGGAYAARTCNTTYGGNGAYMGNMGNCARMGNCARMGNGGNTAYTAYGAYTAYMGN CARMGNGARGARGTNGTNGAR---AGYGAYACNTAYGAYGTNYTNAGYACNGGNTCNMGN AARGGNAAYGCNAAYCAYYTNYTNAAYTTYAARTTYAGYCARCAYGARGAR--------- ------CAYMGNTGGTAYGAYAARAGYMGNTCNAAYGCNCAYAGYMGNGGNGGNTAYMGN AARACNACNMGNTAYAARAARGARCARTTYYTNCARGCNAGYTGYCARTTYGTNGTNMGN GAYACNGARGARTAYACNGARCARGCNATHAAYCCNGAYGTNYTNGTNGAYTGGAAYATG ATHGARYTNGTNMGNAGYTTYTCNACNGARTAYGTNAAYTGYCCNATHTGYYTNCARATH CCNACNGCNGGNAARATHACNAARTGYGGNCAYACNTAYTGYTGGGCNTGYATHYTNCAY TAYYTNAARYTNGGNGARAARGAYATHMGNAARTGYCCNATHTGYTAYGAYACNATHGAR YTNGGNGAYYTNAARAGYGTNGARTGGATHGAYGTNCCNGAYTAYAARATHGGNGAYACN ATHGARATGAARYTNATGCARAARGCNAARGGNAGYATHTTYGTNGTNCCNAARGAYCAR TGGGARGAYMGNAARGGNAARCCNATGAAYATHGARGARGGNTAYAAYACNAARTAYATG AARYTNYTNGTNGCNTCNTAYGAYCARATHCARACNGGNGTNATHGAYMGNGARMGNATH GCNYTNACNAAYCARYTNYTNGAYGCNGARGARTCNGARACNTGYTTYATHCARATGGCN YTNGAYTAYYTNMGNACNMGNGARYTNTCNYTNAARNNNAARTCNTCNAGYAARGARGTN AARAARAAYAARYTNTAYATHCCNGGNYTNAGYTCNGCNGAY------------GTNAAY AARGCNMGNGAYTCNATHCARGARMGNAAYGARATHACNGTNTAYGARGAYGCNTTYGAR GAYAARACNGAR------------------------------------------------ ------------------------------------GCNTAYGAYGAYATHGAYTTYAAY TCNGTN------------------------------------GAYGTNGARGARATHCAR AARGARGAYGAYGCNACN------GTNACNAGYGARYTNGGNGCNTCNGTN--------- ---------GAYAARTTYMGNMGNMGNAAYGAYAGYGGNGAYTCNYTNCCNTTYGGNTCN CCNCCNTGYCCNTTYCCNYTNGTNYTNGAYCARGARGTNAAYTCNGTNGCNYTNAGYYTN GARGARACNGCNGARCAYYTNGARYTNCCNATGGAYGTNCCNCARGCNCARCARCARTCN AARAARGCNTAYACNATGAAYACNAARGAYACNTAYTAYTTYTAYCARGCNTCNACNGGN CARCAYATHTAYYTNAGYTCNYTNAAYGCNCARTGYYTNGCNAARGARTAYGARTCNYTN GARGAYAGYCCNACNACNATHAGYGGNACNGTNGTNGCNATHGARMGNATHTTYATGACN GARGAYGTNMGNAARMGNYTNMGNTAYYTNGGNCAYATHCCNYTNACNTGYGARTTYCAY GTNGTNGARYTNAARATGAARCCNCCNGTNGTNAGYAARGARACNYTNAARTTYTTYGAR GCNGCNTTYGARAARAARMGNAARYTNMGNCARCARAARGCNAARGARGARAARMGNMGN GCNAARAARTAYGARATGGARCAYAARAARTCNTTYGGNATHTAYCCNGARGTNCARATH CCNYTNGAYAAYYTNAAYCARTTYCCNTCNCAYYTNACN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATHACNYTNYTNGAYYTN CCNTGGGARCARGTNYTNTGYMGNAGYGTNYTNCCNTAYYTNAGYATHCCNCARYTNTTY MGNYTNMGNGCNGTNAGYCAYACNTCNYTNTGYYTNGTNGARACNTAYTTYAGYYTNCAR TTYCAYYTNAAYATHTGYGARTTYGGNAARGAYYTNACNCCNGGNGCNTTYTCNATHGTN ACNMGNGARAGYACNAGYYTNAARACNYTNATHYTNMGNGGNGCNAARTAYGGNYTNACN AAYGARGTNTTYYTNCCNGTNATHTCNAAYAAYTCNMGNYTNGARAARATHGAYYTNAGY GGNTGYATHTCNYTNACNGGNTGYGTNYTNTAYGCNATHGGNGCNAAYTGYCCNAARGTN AARCARYTNATHYTNMGNGAYTGYGTNACNTTYACNGAYGAYAAYTTYYTNTCNTTYYTN TGYGCNCARCARCCNYTNAGYYTNGARTAYYTNGAYATHTCNGGNTGYTGGAAYYTNGGN GAYGARYTNYTNGTNAARYTNGTNCARTGYTGYMGNAARYTNAARCAYYTNYTNYTNGGN AARYTNTAYGGNYTNTCNGAYMGNGCNGTNTGYGCNATHGCNCAYTCNTGYCCNAAYYTN GARTCNYTNAGYYTNTGYGGNTGYTGGMGNGTNACNGAYGAYTCNATHAGYYTNATHACN GCNTAYTGYCCNAARYTNMGNYTNYTNCAYGTNAARGARTGYMGNGAYATHACNGARAAR AGYYTNAGYCCNYTNMGNGARAARCAYGTNCARATHGAYAARCCNTCNCCNCCNCCNTCN TTYYTNAAYMGNYTNGARTAYYTNAAYAAYGCNCARMGNATHAAYGTNATGYTNGARAAR ATHGTNYTNTAYAAYTAYTTYMGNAGYTCNGCNAGYTGGMGNGTNMGNATHGGNYTNGCN YTNAARGGNYTNAARTAYGARTAYGARGCNGTNCAYYTNGTNAARGGNCARCARAARACN GARGARTAYAARAARATGAAYCCNATGGGNTGYGTNCCNACNYTNAARATHGAYGGNYTN ACNYTNAAYCARTCNATGCCNATHYTNGARTAYYTNGAYGARMGNAGYCCNGARCCNCCN YTNYTNCCNAARGAYAGYGCNGGNMGNGCNMGNGTNMGNGCNATHGCNGARGTNGTNAAY AGYGGNATHCARCCNYTNCARAAYYTNAARGTNYTNCARAARATHGGNGAYACNAARGTN GARTGGGCNAAYTTYTTYATHACNGARGGNTTYGGNGCNYTNGARGCNATGYTNAARGAR ACNTCNGGNACNTAYTGYTAYGGNGAYGARGTNACNYTNGCNGAYGCNTGYYTNGTNCCN CARGTN---GCNGCNGCNTCNMGNTTYAAYGTNGAYATGTCNCARTTYCCNACNATHAGY MGNGTNAAYAARGCNYTNGARGARYTNCCNGCNTTYAARGCNGCNGAYTTYMGNMGNCAR CCNGAYACNCCNGARGAYYTNMGNATHGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------MGNAAR TCNMGNACNCCNCCNAAR---------TCNTAYAGYMGNGGN------------------ ---------MGNMGNTCNMGNTCNMGNTCNMGN---------------MGNAGYMGNTCN MGNGAYMGNAARGARAARGTNAARGARMGN---------AARAARAGYMGNTCNCCNCCN CCNACNYTNGTNMGNGARGGNTCNGCN--------------------------------- ------------------------------------------------------------ ------ACNGCNGGNGAYGARMGNGARACNTCNCCNGCNAARGGNAAY------GARMGN TCNCCNAGYCCNCCNAARGCNMGNAARMGNAGYYTNACNCCNAARMGNMGNAGYMGNTCN MGNTCNCCNAGYMGNMGN---AARAARMGNMGNCAYTCNMGNTCNACNTCN---MGNAAR MGNTCNMGNTCNMGNAGYGGNTCNMGNCAYMGNTCNMGNAARGAYMGNAARMGNAGYMGN AGYMGNGAYMGNAARCAYGAY---AGYAARAARAARAGYAGYMGNGARAARGAYGAYAAR AARAARGARTCNTCNTCNTCNTCNAARATHAARMGNGAYTAYGAYGARGARGARAARGGN TTYGCNAGYGGNAGYGARGARMGNGAYAAYAAYAGYGAYGGNGGNGGNTCNGGNGAYTCN CCNACNGARCCNCCNGTNYTN---------GARAARGAYACNGAYCAYCARACNGTNGAY ATGGAYATGAGYGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARATHTCNCAY ATGATHGCNTTYATHGAYCARGARGCNTGYGARAARGTNGARGARATHGAYYTNAARGCN GARGARGARTTYAAYATHGARAARGGNMGNYTNGTNCARCARTCNMGNGTNCARATHATH GAYTAYTAYGAYAARAARATHAARAAYGTNGARYTNCARAARAARATHCARAAYTCNAAY ATGCARAAYAAYGCNMGNYTNGARATHYTNMGNAARAARGARGARTAYGTNAARGARGTN ATGGARGARGCNMGNGARAARYTNAARAARGTNATHMGNGARAAYCCNAARGARTAYGAR MGNYTNYTNTCNMGNYTNATHATGCARGCNYTNGCNMGNYTNATHGARAGYAARGTNACN ATHMGNTGYMGNMGNGARGAYGTNAARYTNATHGARAGYTTYATHCCNGGNYTNCARAAR GARTAYAARGARYTNYTNAARGGNAARTAYTCNYTNGARYTNGTNATHGAYCARGAYAAR TTYYTNTCNACNGARATHTGYGGNGGNGTNGARYTNCAYGCNATGAGYGGNAARATHGTN GTNGTNAAYACNYTNGAYGARMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGGGNAARAARCAYAARCAYGGNAARCAY--- TCNTCNTCNTCNTCNAGYAGYTCNAGYAGYGAYTCNTCNGAYGAYGARTGGMGNCAYYTN CCNAARCAYGARAARAARATGMGNAARAARTGGAARAARAAYATGMGNACNGGNAARATH CCNCAYGGNCARATGCCNCCNTGGCAYGGNGGNCCNGCNTGGGCNCCNCCNATGAARGCN GGNAARAARGGNCAYAARGGN---------------GGNGCNGTNCAYTAYCCNGCNGGN GGNCCNGCNGGN------GGNTAYACNGCNCCNGGNTAYCCNGCNCCNCARCCNGGNTAY CCNGCNCARCARGGNTAYCCNCCNCCNCARGCNGCNTAYCCNCCNCCNCARGCNGCN--- TAYCCNCCN---------CCNCARGCNGCNTAYCCNCCNCCNCCNGGNGCNTAYCCNGGN GCNCCNCCNCCNGGNGGNTAYCCNGCNAGYGCNTAYCCNCCN------------------ ------CCNCCNGCNGCNCARTAY---GCNCCNCCNGGNGGNGCNTAYGGNACNCAYGGN GCNCCNTCNGGNCCNTTYCARCCNCCNCCNGGNGGNGCNTAYCCNCARCCN------GGN TAYCCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AARACN YTNGCNMGNMGNGCNAARACNGTNMGNTAYGARAAYMGNAARMGNTCNTCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARGARGARATHTGYMGN ATGTGYGAYMGNTGYTTYCARYTNMGNTGYTGYMGNYTNTTYACNAAYTCNAGYYTNCAY AARYTNYTNMGNYTNMGNGAYGCNTGGGCNACNTCNATGATGTTYTCNATGYTNTCNACN ATHACNATHGTNATHGAYGARYTNTTYCCNGTNTTYGCNTCNACNMGNACNGAYTGYGGN GGNYTNGGNTTYTCNAGYAAYAARATHGGNATGGCNATHGGNATHYTNACNATHCCNYTN GTNACNGTNCARATHAARYTNTTYCCNTTYYTNGTNAAYAARYTNGGNATHMGNAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARGGNTGYCCNATHCCNTTYMGNYTNATG MGNGARTGYGARGGNGTNAARGARGGNGTNGTNCCNYTNTCNMGNGAYGGNYTNGTNTGY ATHAARGARAAYAARTGYTAYMGNCCNGCNTGYACNGTNGGNAARTTYGAYGTNAARACN GGNTTYTGYCCNYTNTCNGAYAAYTAYAGYYTNCARCCNTAYYTNTTYAARGAYCCNGAR GARMGNMGNCAYTAYMGNAARCAYYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGNATHGTNGTNGTNGAYTTYGTNATHTCNTGYGTNYTNACNYTNTTY TGGATHATHGCNTCNTCNGCNTGGGCNGCNGGNYTNGAYGAYGTNAARYTNTAYACNGAY CCNTCNGAYGGNGGNATHTTYCCNAARGGNATHGARGARTGYMGNGARAARAAYGCN--- TGYTAYACNAAYAGYGGNGGNAAYTTYGCNAGYYTNAAYGTNTCNATHATHTTYGGNTTY YTNAAYTTYGTNGTNTGGATHGGNAAYYTNTGGTTYYTNTTYAARGARACNCCNTGGTTY AARGTNCARGCNAARCCNCCNAGYCARCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TTYCAYTGGTCNTCN ACNGCNCCNYTNAAYGAYYTNATHYTNCARTTYGARGARACNYTNTCNAGYTAYCARCAR TTYTGGGAYTAYYTNGARGAYATHGAYAARAAYACNTGGGTNATGGARCCNGARCARCCN ACNTAYTCNTGYGTNTAYMGNMGNATHGCNTTYGGNCAYAAYYTNTCNYTNCAYATHGTN ATHAAYCCNATGCARCCNTCNGGNYTNCCNGARTGYMGNYTNYTNGGNGCNGARTCNGCN GTNGCNCCNYTNMGNGARAARYTNAAYATHAAYYTNCAYCARTGGGAYYTNGAYMGNTCN YTNYTNAAYAAYYTNCARGARGTNYTNGARATHGAYTTYCCNTCNCCNTCNGAYACNATG AARGARGARYTNAGYGTNGARTGYGGNATHTGYTAYAGYCAYCARYTNGGNGARGARATH CCNGAYATHGTNTGYCARCAYCCNCARTGYAGYCARGTNTTYCAYTAYACNTGYYTNTAY GARTGGYTNMGNAAYTCNTCNTGYMGNCARAGYTTYAAYTAYATHTTYGGNGARTGYCCN TTYTGYAGYAARCCNATGMGNGTNAARATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARAARAARGCNYTNAARGCNCCNGCNAARCAR YTNGCNAARTCNTCNGCNYTNGCNTCNYTNTCNTCNYTNGGNYTNGGNTAYGGNTCNGGN AGYGAY---------AGYGAYGARGARAAYGARAARGAYGARGAYTCNGAYAGYGAYYTN GARGARACNATHMGNMGNAARAARGCNGARTTYGCNAARMGNCARMGNATHTTYAGYGAY GCNGAYGAYAAYGAYGCNMGNGGNGAYMGNACNMGNGAYGGNAARACNAGYGCNCARTCN GGNAARGAYAGYGARAARAGYAAYAARMGNCARAAYGAY---------MGNMGNGAYTCN GAYMGNAGYGTNAARTCNGARMGNMGNGAYAGYAARGARAAYAAYGCNAARAARGAR--- GTNCCNAAYMGNMGNTGGGAYTCNAARTCNAARCCNGTNAGYCARACNGAYACNGAYAAR YTNATHGAY---------------------AARGCNGARAAYATHAGYAARCARACNGAR ATHGAYACNGARAARACN------------------------------------GTNAAR AARGARGARAARAGYAARGARMGNACNATHGAYAARAARGARGTN--------------- ------------GTNAAYGTNGAYAARAGYAGYAGYAGYAGYAGYGGNACNAGYAGYAGY AGYGGNAGYAGYGGNGAYAGYAGYAGYGGNTCNTCNAGYGCNGAYTCNGARGAYAGYGAY ACNGGNAGYAGYAGYGCNGGNGARGGNGGNAGYTCNTCNTCNTCNTCNTCNTCNTCNTCN TCNATHTCNAARCCNAARAARGAYATHAARAARTCNMGNCARCARGTNAARATHGAYAAR AARGARAARTTYGAYATHGARAARAARAARGAYGAYMGNAARGAYTAYACNAARATGTCN MGNTCNGGNAARAAYACNGARGCNAARTCNCCNMGN------------AARGARAARGTN GARCAYAARGARAARACNAARMGNAARAGYMGNGARAARMGNAARMGNAGYAGYTGGGAR GARGARAGYACNAARGAYTCNATGACNGGNAARAARATHAARTCNGAYAGYMGNGARTAY GARGAYAGYGARGARMGNMGNMGNAGYMGNAGYAAYTCNAARGAYGTNTCNMGNMGNAAR MGNYTNMGNAGYGAYTCNAARGAR---YTNTTYGAYMGNAARMGNGGNMGNAGYMGNAGY GARTCNMGNGAYTAYYTNMGNGCNAARMGNCARMGNAGYMGNAGYAGYTCNMGNGAYAAR MGNMGNCAYMGNAGYMGNAGYAAYTCNTTYGARGTNTCNMGNGAYMGNAGYTAY------ ------AARAGYAARAARTCNMGNMGNGAYTCNYTNTAYAGYGARGARGARAARGAYMGN MGNMGNTTYGAYMGNAGYGCNAGYMGNGARGAYAAYMGNMGNAGYMGNAGYATHGAYAAR ACNMGNAARMGNAGYMGNAGYAARGARAGYYTNAARTAYGARAARTCNTCNMGNAARTCN GGNGGNGGNGAYMGNTAYMGN------------GTNAARTCNGARAARAARMGNAARGCN CAYTCNGARTCNTCNGARAGYGARGGNTCN------MGNAARYTNAARAARAARAARTCN AARTCNAARCAYMGNMGNCCNAGYTCNGARGARGTNTAYMGNGARGAYGGNAARACNGCN AARAAYAARMGNCAYGGNGGNMGNTCNMGNTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARAARAARAGYYTNGTNCARGTNCARGARGGNYTNACNGAR GTNCARGGNCARYTNMGNCAYAARGAYCARAAYYTNMGNCARATHGGNAARCARYTNGCN CAYATHGARTAYGARMGNGAYTCNYTNCARAGYAAYYTNAARGAYGCNGARAAYGCNYTN MGNACNGCNGCNMGNGAYAARGARATHGTNGCNCARTAYATHAARAGYGTNGGNAGYGCN YTNGARTCNGCNAARAARCARTTYYTNATHATHAGYGARCCNCCNCCNYTNTCNAARGAY GTNTCNYTNTCNMGNYTNYTNYTNGAYGCNGAYYTNATHCCNYTNGAYATHGGNAARGCN GGNCCNGARYTNATHGCNYTNCARAAYYTNGTNGGNGGNTTYGTNGAYGCNCARCAYCAR GCNGTNAAYAARATHMGNTCNYTNGARGARGARATHGCNTCNCAYMGNAGYCAYATHGAR TCNYTNAARAARGARYTNAGYAAYGCNGTNCARMGNGARTTYAGYCARCARYTNGCNTCN GCNACNGAYGGNGCNTTYTCNGARGCNACNGAYCARGARGAYGAYYTNGTNCCNYTNAAR GARGAYCCNGAYATHTCNTTYGARAGYYTNCCNACN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TGYGCNGAYGGNAARTGYGAYAAYGGNTCNAAYGCNCCNGTNGCNGTNATHGTNGTN--- GTNGTNGTNYTNATHGCNACNYTNGTNTGYGGNGTNTCNGGNTGGGTNTAYTAYGCNTAY ACNCAYCCNACNTCNMGNTCNGGNATGTGGYTNATGGARCAYMGNCCNAGYCARATHAAR GCNAARATHAARTTYTGGAARGGNAGYAGYAGYTCNGGNGCNAARTAYMGNGCNGARGCN GAYGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TGYCCNAAYCCNGGNAGYCAR GAYAAYTTYGARACNAGYGARTAYYTNGGNAARTGGTAYGARYTNGARMGNTTYAGYGCN TGGTTYGARYTNGGNGTNGTNTGYGGNAGYGCNAAYTAYAGYATGAAYGAYGAYGGNAGY ATHAARGTNATHAAYGGNGGNAARMGNATHATH---------------YTNGGNATGGAR TCNCCNACNTCNATHGTNGGNAARGCNACNGTNCCNGAYCCNACNMGNCCNTCNGARYTN MGNGTNTCNTTYTCNAARTTYGAY---CCNGGNACNGGNCCNGCNAAYTAYTTYGTNGTN GAYACNGAYTAYACNACNTAYACNGTNATHTTYTCNTGYACNGAYYTNATHGGN---CCN TTYAGYATHCARTAYGCNTGGATHYTNACNMGNGAYMGNGGNGTNCCNCCNGCNAAYYTN GARGCNYTNAARTCNAAYYTNGCNTCNCAYGGNGTNAAYYTNGAYAAYTTYAAYCAYGTN GAYCARTCNGAYTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARTAYGAYAARTTYTTY CAYAGYAGYGGNACNYTNTTYCARGARACNGCNGCNTTYMGNGCNMGNCARGARYTNGCN MGNCARCARMGNGARGARYTNYTNMGNAARNNNGARAARAAYGARATGATGYTNAARGGN AARGGNAARAARGAYGGNYTNMGNCCNGARAGYCCNGGNMGNAARMGNMGNYTNAGYCAR MGNCCNACNYTNCCNYTNMGNCAYYTNGGNCARMGNCAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNGTNMGNMGNGTNGTNGGNGGNGARCAR ATGGCNATGGGNGCNTGGCCNTGGYTNGTNTCNYTNAAYTAYAARGARCAYCAYGTNTAY YTNGARYTNCARGGNYTNGAYCAYYTNTGYGGNGCNACNYTNATHCAYCCNTCNTGGGTN ATHACNGCNGCNCAYTGYGTNCAYTAYATGTCNGGNAGYGARGGNYTNGGNATHGCNTCN AAYTGGGTNGCNGTNYTNGGNGARTAYAAYMGNMGNGTNGARGARCARTCNGARCARMGN YTNCARGTNGARGARATHTAYGTNAAYCCNAAYTAYACNYTNTTYCCNAAYYTNACNGGN GAYATHGCNYTNYTNAARYTNMGNCAYCCNGCNMGNGTNACNGGNGCNGTNMGNCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TGYAGYMGNCARAARCCNATHAARTTYYTNATHCARGGNYTNGAY GCNGCNGGNAARACNAGYYTNYTNTAYAARYTNAARYTNGGNGARATHGTNACNACNATH CCNACNATHGGNTTYAAYGTNGARTCNYTN---TAYAGYCAYMGNGTNGARATHGTNGCN TGGGAYGTNGGNGGNMGNGAYAARATGMGNGCNYTNTAYMGNCAYTAYTAYCCNGGNACN GAYGGNTAYATHTAYGTNATHGAYTCNGCNGAYGTNGARMGNYTNGAYCARTCNYTNGAR GARYTNAAYGAYTTYYTNYTNAARAGYGARGARGTNGAYGGN---GTNYTNATGATHYTN GCNAAYAARCARGAYYTNAARATGGCNYTNAGYCCNGCNCARATHCARGCNAARGTNGAR GARAAYTGYAAYACNTCNGCNAAYYTNTCNGTNTTYGTNATGCCNTGYAGYGTNGTNACN GGNGAY------GGNYTNTGGGAYTCNTTYCAYTAYYTNGTNCARCARGTNAARYTNMGN AARGAR------------------------------------------------------ ------------GGNAARYTNCCNAAYGGNYTNATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYTCNYTNCARGARTGYGTNCCNGAR YTNYTNAARGTNAARATHGAYGTNTGGTCNAARGTNGAYAARATGGTNGAYAGYAARGTN ATHATGTCNACNTCNACNAGYGCNYTNYTNCCNTCNGCNATHTCNCARGAYYTNGARCAY AARAAYMGNTTYATHGTNTCNCAYCCNACNAAYCCNCCNTAYTAYGCNCCNGCNACNGAR GTNGTNCCNTCNAARTGGACNGAYCARGCNGTNGTNACNAARACNATGGCNYTNYTNGAR GARGTNGGNCARGTNCCNATHYTNGTNAARAARGARATHAAYGGNTTYGTNYTNAAYMGN ATHCARTAYGCNATHATGGGNGARGCNTAYMGNYTNATHCARGAYGGNGTNGTNAGYCCN MGNGAYGTNGAYYTNATHATGTCNCARGGNYTNGGNATGMGNTAYGCNTTYATGGGNCCN TGGGARACNGGNTAYYTNAAYGCNGARGGNATGATHGTNTAYGGNGARMGNTAYTCNGAY ATGATHYTNGGNATHCARGARACNTTYAARAGYCCNGARMGNATGGARGGNGARACNYTN AARYTNATHCAYGARGAYATHGCNAARGTNGCNGGNCCNGTNGARGAYATHCARAARMGN MGNGAYTGGMGNGAYMGNMGNYTNGTNGCNYTNGCNMGNYTNAARGCNGARATGGAYCAR AARGAYGCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GCNCARATHCCNGAYYTNGTNACNTGYCCNTTYTGYCCN TTYGCNACNATHATGCCNAAYCCNGAYGAYAARGTNYTNAARTGYYTNAAYCCNGARTGY YTNAARGARTCNTGYMGNYTNTGYMGNGARGAYAAYCAYATHCCNYTNAARTGYAAYGAR GTNGARAGYMGNGCNGGNACNMGNATGMGNACNTAYATHGARAAYAARGTNGCNGARGCN GTNATGMGNAARTGYCAYMGNTGYGGNAARMGNTTYYTNAARGAYGCNGGNTGYAAYAAR ATGACNTGYGTNTGYGGNGCNACNAGYTGYTAYTAYTGYAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNACNYTNTGYMGNAAYYTNATGGTNACN---MGNACNYTNCAR CARGARGGNGARAARGTNCCNGARACNGAYGARGTNGTNACNCCNAARMGNAARGTNGTN GAYGTNGARACNAGYATHMGNTAYYTNAAYAGYAARGCNTTYGTNGARGGNTAYGGNGAY AARCCNGTNTGGTTYCAYTAYMGNMGNAAYTTYAARGGNACNATHATGCCNCCNACNMGN AARACNTGYATHMGNAARGGNGARATHTCNACNTCNAGYCCNTGYCCNATHTGYMGNGAY GARTAYYTNATHYTNGAYGCNAARAAYACNAARYTNYTNGARCARTTYATHTCNCCNCAY ACNGGNGARATGTAYGAYTCNATGAARACNGGNYTNTGYAARAARCARCARMGNACNYTN GTNGTNGARGTNATGAARGCNTGGGAYCARGGNTAYYTNGARATGAARGTNCCNTTYMGN ACNTAYGAYTAYGAYGARTAYMGNAGY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AGYGAYYTNAAYCCN TTYGCNGGNYTNGTNATHGCNGAYTCNTCNTTYYTNGAYGAYAGYTCNTTYMGNACNAAR TGYGTNAAYTGYAGYAARTCNMGNAARTAYTAYTGYTAYAGYTGYTGYATHGCNYTNCCN CAYYTNCARGGNMGNYTNCCNATHGTNAARYTNCCNYTNAARGTNGAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GAYTTYMGNGCNGARGCNGGNGCNGTNGTNTCNGTNCCNGTNGTNGAYGAY GARAARGTN------GAYGGNMGNAGYAGYGTNGARGTNAARGARAAYGGNGARTAYMGN GGNGARGAYMGNAAYGARGTNTCNYTNCCNGAYGGNACNGARGAYAGYMGNGGNCARGGN CARTGGCARTCNGCNGARCARCARTAYTTYGCNTCNGCNATHCARGTNCARAARAGYGAR ------------AARGAYGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------TTYAARGARGTNGARGARGAYMGN GAYMGNYTNYTN------GARGAYCARAARGAYATGAARATHAARGAYYTNCARGARMGN YTNGCNATHYTNGCNMGNGARAAYGARGARAARGAYGARMGNATHAAYAARYTNACNGCN ACNYTNGAYGARACNTCNTCNMGNYTNAARGARACNGARMGNMGNYTNATHATHTCNGAR CARGCNAAYGCNGARMGNCCNGARGCNCCNAARTCNAARACNTGYGTNATHATG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNTTYAARAGYGAYGTNAGY YTNGAYAARYTNTAYCCNAAYTCNAAYCCNGAYTAYYTNMGNCCNMGN---GAYCAYCAR AARCARAAYGARACNACNGARATGTTYTCNGGNCAYATHCCNGTNGARCARYTNGARATH AGYCAYAGYMGNAGYGGNGGNCCNGGNGGNCARAAYGTNAAYACNGTNAAYAGYAARGTN GARATGMGNTTYCAYYTNGAYTCNGCNTCNTGGATHCCNGAYTGGATHAARCCNMGNYTN GCNGAYCARGARGARAAYMGNATHACNAARAAYGGNTTYYTNATHGTNAARTCNGAYATG ACNMGNAARMGNATGYTNAAYCARGCNGAYTGYYTNAAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CAYCAYAARGTNGTNTGYCCNTCNAAYMGNGAR TCNACNGCNGCNATGYTNTAYGAYGTNMGNMGNTCNTTYMGNGAYGTNATHGCNGCNGAY GGNTCNTCNTGGCARGGNTGGTGGAAYGCNGARTTYAGYCCNACNYTNYTNTCNMGNATG ATHGCNATHGTNYTNTGYAAYGCNAAYYTNYTNGCNGAYYTNMGNACNAARGARTCNTAY ACNGAYAGYCAYTGGTCNATGTGYGARGCNATHYTNGARAARTAYTCNCCNTGYGAYAAR ATHCARGCNGCNGAYAAYATHCCNAARATGCARGARYTNYTNAAYAAYYTNTTYAARMGN TCNAARTTYYTNMGNTAYAAYYTNACNAARACNGAYTTYAAYAARMGNTAYTCNCARGCN GCNACNAAYGCNATHGGNTTYCAYGAYAAYACNAAYCCNATGAAYAAYTTYTCNGARTTY CAYGGNYTNTTYCCNYTNGCNTGYTGYYTNAAYCAYTCNTGYTTYCCNAAYGCNAARATH GARTGYGCNGARGTNGARGCNMGNCCNGGNATHGTNGTNAARGCNGTNMGNGAYATHAAR GCNGAYGARGARATHGTNGTNTCNTAYGTNGARCCNYTNGARGARMGNCAYGARMGNMGN GGNAARYTNTGGMGNAARTAYAARYTNATHTGYGAYTGYCCNMGNTGYYTNCAYGARGGN GTNGGNCCNCAYGTNTGYACNAAYTGYGCNAARAARGCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GCNTAYYTNAARATH YTNATGGARAGYTCNAAYGCNGAY---TGGYTNTCNTCNATHATHGAYYTNAARAAYGCN GTNATHGGNAGYAAYAARGARAARTGYMGNGTNGTNCARCARGGNYTNGTNTCNMGNYTN YTNAGYTGGGTNGARGARGARTCNTGYCCNATGGAYYTNAARACNGARTCNGCNATHGTN YTNGGNAGYYTNGCNAARGGNGGNMGNGARACNGTNAAYAARYTNGTNCARGCNAARGCN GTNCCNATHYTNYTNAARTCNATHAAYACNTCNAAYYTNAARTAYACNGARGCNGTNYTN MGNTGYYTNMGNTCNATHTTYATHGARAAYACNGAYGGNACNGAYTAYYTNTAYGARGAR AAYACNTAYAGYACNTCNTAYATHCCNACNTTYYTNGCNATGACNCARCARTCNACNGTN TGYCARGARTGYGTNACNAAYATHYTNGTNTGYGGNTGYAARACNMGNGAYCAYCARATG TGYYTNYTNAAYAGYCARGCNYTNCCNATHYTNTCNCCNYTNYTNCARTCNAAY---CAR TAYAARATHCARATGCCNACNYTNMGNTTYTTYGCNAARATGTGYTAYAARAAYCAYGAR GTNTGYTCNGCNATHGCNCARGAYATHAARYTNATHACNACNTTYGTNMGNYTNATGGGN MGNGAYAARCCNACNGARATGCARATGGCNGCNGCNGARATGYTNACNAAYYTNCAYMGN TGYGGNGTNATHCCNGCNAGYGAYTTYATHATHAGYMGNAARACNYTNGGNACNYTNGTN MGNATGTGYATGMGNGAYMGNACNGTNGARGARAAYGTNMGNGGNGCNGARGTNYTNGCN TAYYTNGTNGARATHGARCCNGAYYTNCARGTNATGGCNAGYTAYACNGTNCAYYTNATH GGNGCNYTNTCNACNTGYYTNAAYTAYCARGAYAAYAGYMGN---------------CAR CARGAYGTNGAYTGGGGNAGYGARATGMGNMGNGCNGCNTTYYTNGCNTTYGCNTCNATH AGYGCNAAYGAYGARGARATHMGNGARAARGTNATHAARCARGAYGGNATGATHGARCAY ATHCARACNGCNYTNTCNAGYAAYCAYGARGGNGARGTNGCNGCNAGYYTNMGNTGYYTN CARTCNYTNACNMGNTCNGTNCARCARATHMGNACNGTNYTNCAYGAYAAYACNGTNTGG AARCCNYTNYTNGARAARGTNMGNTCN------------------AAYMGNGARATHATG GTNYTNGCNATGTCNTGYYTNTGYAAYYTNGTNYTNGARTTYTCNCCNAGYAARGARGCN YTNGTNGARAAYCAYGCNGTNGAYGTNYTNTGYGARYTNTGYAAYAGYGAYGAYAAYATH GTNMGNYTNAAYGCNACNTGGGGNATGATGTCNATGTCNTAYTGYGCNTCNGARGARYTN GGNATHAAYATHATHAAYAARATGGGNCCNGARACNATGGTNCARMGNATHCARGAYCAY ATHYTNYTNATHMGNGARAARGCNYTNTGYYTNGTNMGNAAYYTNYTNACNGGNAARATG AAYATHGAYAAYACNGTNAARYTNYTNGGNACNGARGTNATHAARGCNGTNTTYCARATH YTNTCNGAYCCNGARATGCCNTGYAAYATHGTNACNCARGCNYTNTGYGCNYTNAGYAAY ATGGCNGAYGGNCCNTCNTGYAARGCNTAYATHATHGGNAARACNGAYGARATHAAYTCN GTNGTNAARTAYYTNCARTAYCCNGARAARAAYYTNCARYTNCCNGCNATHCARTTYGTN AGYAAYYTNGTNGAYACNAGYGAYGAYGAYTTYGGNCCNTTYCCNGGNGCNGGNTCNTAY CARMGNATGYTNCARYTNAARACNYTNGGNGTNCARACNYTNYTNGARAGYYTNGTNGGN ACNGGNATGGARGARGTNGARYTNMGNGCNCARCARGCNYTNAARTTYTTYGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY TAYAARMGNCAYCCNMGNAAYTAYGGNGGNGGNGCNGAYYTNACNAARGTNAARGAYACN ATGAARACNATGMGNGARAARGARMGNGARMGNCCNGCNTCNAAYAARCCNYTNGAYATH GTNATGACNGGNMGNGARMGNMGNAAYCAYGARCARTGGAARCARGARMGNGARMGNTAY GAYAAYGARMGNATHCARMGNCARYTNGGNGARGGNGGNCAYTGGAARMGNGARTGGGAY CAYGAYAARGTNGTNYTNGARTAYGAYGAYTCNCCNTAY------TCNAARATGGARCCN GCNAARMGNCCNGCNGGNMGNATHGGNAGYGGNMGNTTYGAYMGNGGNGAYMGNGAYGAY MGNCCNMGNGCNCCNAAYMGNGAYGGNAARGGNGGN------------------------ ---------------------------------------------------------CCN CARCARCAYCAYCCNAAYCARGCNGGNCCNGCNAAYCAYCAYCAY---CCNCCNCCNCAR AGYCCNCARCCNGGNGAYGGNAARGTNCCNMGNGGNAARGGNMGNGGNMGNGGNMGNGGN MGNGGNMGNGGNGTNACNCARGGNACNGGNATGGGN------GAYAARTCNCCNMGNCCN MGNACNTGGTCNGGNGGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHGAYGCNAAYGGNCCNMGNCCNGARCCNGTNTAYYTNMGNMGNGAR AARCARCARCCNCCNAGYYTNGTNGCNTCNAARCAYCCNCAYGGNACNAGYCCNACNAAY GGNAGYCAYCCNCAYACNGGNCARCCNMGNCCNYTNMGNTAYGGNAAYGAYAAYAGYAGY GTNAAYMGNCARTCNMGNACNCARAGYACNMGNCCNGAYCCNATHCARGGNCARCCNTAY GCNGGNGCNCCNGCNCARMGNGTNGGNAGYGCNCCNYTNMGNAARATGGGN---AAYCAR TCN---------MGNACNAAYGGNGGNGTNATHAAYMGNTCNACNYTNACNAGYGARACN GGNYTNGARCARGTNCARTCN--------------------------------------- CARCAYCAYCCNAAYTTYYTNCCN------------------CCNATGCCNMGNCCNCCN CARGCNTCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GAYACNGAYTGGAAY AGYTGGAGYGAYACNTGGGTNAAYGARGARGAYCARTGGACNGGNACNYTNGARGARACN AARGTNTTYACNCCNTCNCAYGTNAARATHCCNGARCCNGAYCCNATHAGYAAYGARCCN CCNAGYTCNYTNGGNCARMGNYTNGAYGTNGGNAGYYTNTTYGARAAYGCNAARTTYACN AARGCNCCNGAYTAYAGYAARCCNAGYGGNGAYTCNTAYATHACNCARTTYAAYCARGCN GCNACNGARTCNATHAARAAYACNATHGGNATHGGNAGYACNTCNMGN---CCNCAR--- ---------ATGGGNYTNTCNCCNCARAAYTCNTCNAGYTCNYTNGGNYTNTCNAAYYTN GGNCARAGYTCNGGNCARGTNCARGGNAAYGCNGTNYTNTCNCCNYTN---CARCARTCN GGNACNCAR---AAYTCNATGCCNCAYGCNATGGCNCARYTNTCNCARATHTCNCARCCN GCNTCNCARACNCCNAGYATGTCNCARATGGGNATHGGNTCN---CARTCNAGYCARGTN AGYAGY------------------------------------------------------ AGYCARGCNCCNCARCARTCNMGNATHCCNGCNGTNGTNCARCARCARAGYYTNCCNTCN CARACNAGY---------------------ATGAAYAAYATGCARCARMGNCCNAARCCN CARMGNTCNAARYTNCCNCCNCCNTCNAARATHCCNTCNACNGCNGTNGARATGCCNGGN CAYATHCCNMGNAAYCCNCARYTNGAYGTNCARTTYGGNYTNGAYTTYGGNCCNGARCCN TCNGTNCARTTYGGNTTYGGNGGNAGYGGNGAYAGYCCNGCNGTNACNAGYTCNTAYTCN ACNACNTCNAAYGGN---ACNACNGTNATHTCNAAYCAYYTNAAYCARGGNCAYGTNAGY CARTCNGCNGGNGAYGGNAAYGCNGTNTCNAGYATHATGCCNTCNCCNTCNGCNGGNACN GCNAARGTNCCNTCNGGNATGGARCCNCCNCARGTNTCNAAYMGNCCNGGNGTNTTYCAY AAYTCNGTNTAYTCNTCNCCNCARCARAARAAYGARAGYCARGCNYTNGARMGNGARCAR AAYAARGTNAAYGAYTCNATHCCNTTYYTNTCNTCNCARYTNGARMGNAARACNAGYCCN ---ATGTCNTCNCARMGNCCNGGNCCNACNAAYCARAAYYTNAAYGCNGGNCCNATGACN TCNAAYAARAAYGAYTCNCCNTCNTCNGCNAAYGCNAAYAGYTAYTCNTCNGCNAAYTGY TAYACNTCNTCNTCNTAYCARAGYCAYCCNAARGGNTCN---------------CAYACN GTNAAYTCNCARCCNCCNCARGCNTCNTCNTTYCCNGGNCARTAYCCNGTNAAYCARTCN ---TAYCCNACNGCNGGNCARACNCARTTYCCNGCNCCNCCNAAYGCNACNTCNTTY--- CCNACNGCNCARCCNGCNCARTAY---------AAYCCN------AGYCCNTCNCARAAY CARTCNGCNCARAAYCARTAYTCNGTNGGNACNTCNACN---------ATHGCNCAYCAR AAYCARTAYCCNCCNAGYGGNCARAAYAAYTAYGGNAGY---AGYCCNTCNCARTAYTCN GCNTAYCARAAYAAYACNTCNTTYCCNTCNCAYCCNCARACNCARTCNAAYTAYCCNTCN AAYCARAAYGGNGGNACNGGNGCNGTNYTNTAYCCNACNTCNACNCARTCNGGNGTNCCN TCNTAYACNTCNCARTCNAAYTCNTAYCARTCNCCNTCNGCNGGNTCNTAYCAYTCNTCN MGNGAYGGNCCNACNAAYGTNGCNGTNAGYACNCARTCNAAYAGYGGNATHTCNTTYCCN AGYCARCCNCARAAYTCNAAYYTNAARCCNGTNGCNACNCARAGYAAYTCNAGYTTYAAY TCNCARAGYTAYAAYGCNACNCCNACNCARYTNCARCCNTCNGCNYTNGCNAAYAARYTN GGNGARGGNYTNTCNAARATHTCNATHAARGAYTCNTCNACNGTNYTNGAYGGNCAYCAR TCNTCNCARTAYGAYCAYACNCCNTCNCCNGCNAGYGTNCCNACNAGYGTNAGYYTNCCN TCNGCNTCNAGYTCNGCNTCNYTNTCNACNGGNACNAAYACNATHTCNTCNACNTCNACN GTNACNTCNGTNTCNTCNAAYTCNMGNGTNGCNTCNATGCCNTCNACNTCNGGNAARGCN CCNCCNAAYYTNCCNCCNGGNGTNCCNYTNATGGGNCARTAYATHATGGGNCARAGYACN ATHCCNCCNTTYTAYAGYGTNCARCCNCCNYTNTAYGGNTAYGARGAYATGCARYTNYTN CARCARMGNATGCCNATGCARACNGGNAGYTAYTAYGAYGTNAGYGCNTTYCCN---GCN CCNGCNGGNTCNACNYTNTCNGCNGGNMGNGAYCCNCARCCNCCNATHCCNAGYGTNCCN TTYTCNGGNACNTCNGAYACNAARYTNACNMGNGTNGAYGCNCARAGYCCNAAYGCNTCN AGYCARCCNCARAGYGCNCAYTCNGCNGCNCARCARCCNYTNTTYAAYATHCAYTAYGGN TAYTAYTAYCCNTCNGCNATGTAYGGNGCNGCNGGNYTNCARTAYCCN---ACNGTNTTY CCNATHCCNCCNGTNACNAAYGCNGCNGGNCAYCCNGGNACNACNTCNACNTCNCARTTY CARAARTCNTTYCARTCNCAYGTNTAYACNACNAARGGN--------------------- ------------------------------------------------------------ ---------------TCNGGNACNAAYGARATGACNCCNAAYGCNTAYAGYAARTCNCAY GGNCAR---GGNTTYGAYAARCARGGNTAYCAYGGNGGNACNCCNCCNCCNTTYAAYYTN CCNYTNGCNTCNGCNACNCARACNGGNCCNATGGGNGCNCCNGCNACNCCNTAYGGNGCN CCNTTYYTNCCNGTNATGGCNGCNCAYCARCCNCAYTCNCARATGATGCAYCAYCCNATH CARCARGAYTCNAAYAGYACNAGYTCNMGNGGNYTNAAYCCNGCNGGNGGNCARGGNAAR TCNGGNACNACNAARTCNTTY---GGNGCNCCNCCNTAYTGGAAYAAY------------ ------YTNCCNYTNCCNCARYTNTGGGGNATHYTNTTYTTYYTNATGYTNTTYAGYYTN GGNYTNGAYACNCARTTYTGYAAYGTNGARACNGTNATGACNTCNGCNYTNGAYYTNTGG CCNMGNYTNGTNTCNMGNCAYMGNATHATGYTNACNAGYGTNGTNATGYTNYTNGTNTTY ATHGTNTCNYTNCCNTTYACNGCNMGNGGNGGNATHTAYATHTTYCARYTNGTNGAYTGG TAYATHGCNGCNTTYAGYATHYTNTTYATHGGNAGYYTNGARTGYYTNGTNGTNGCNTGG ATHTAYGGNACNGARMGNATHTTYATGGAYATHGARATGATGACNGGNMGNAARCCNCCN TAYTTYTTYTAYYTNGCNTGGAARTTYTTYACNCCNGTNYTNYTNYTNTGYGTNYTNGTN GCNACNYTNGTNACNTAYGARGCNCCNAARTAYGGNAARTAYMGNTAYTCNACNTGGGGN YTNGTNATHGGNTGGTCNATHGCNATHGTNTCNTTYYTNCCNATHCCNGTNACNGCNGTN TGGGARATHTAYAARACNACNGGNACNYTNMGNGARMGNATHMGNAARGTNTGYGARCCN TCNGCNGAYTGGGTNCCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARTTYGTNTAYGTNGTNGTNGAYATHTGYGCNTGYTTYYTNATHTTYATHGCNGCN TGYATHYTNTCNGCNGGNACNAAYGARACNTGYGAYCAYGTNGAYTGYGAYMGNAAYGAY GCN---------GTNTCNGCNTCNAARGCNGCNCARGCNGGNGCNTGGATHAGYACNTTY YTNTGGYTNTTYATHGCNGTNGCNGGNTTYATHACNYTNTGGMGNACNGGNAARATHCCN TTYYTNGGNGGNGGNGGNGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ACN TAYAARTGYTGYCCNMGNTCNTGGAAYTAYCARTGYMGNAGYTCNAGYGTNMGNCARCCN TGYTTYACNTAYTAYTAYCARGGNGTNMGNGARTGGTGYTGYCCNATHTGGCCNTCN--- ---GTNTTYATHMGNAARTGYAAYTGYAGYCARTGYGCNGTNYTNACNTCNACNTGYGCN NNNGARGGNMGNTGYMGNMGNMGNTAYTCNMGNMGNAGYTTYYTNGCNGTNTGYTAYNNN NNNAAYAGYCARTGGGGNTTYYTNMGNTAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGTNTGYGTN CCNTGYTTYYTNATHCCNATHATHYTNTGGGTNTTYCAYAARTTYATHCARCCNTGGYTN TCNAARATHTGGAGYAAYTCNGARAAYTAYGTNACNAGYAAYYTNACNTGYCCNATGCCN CARAAYAARAARAARCCNGTNAAYAGYCCNGARACNAARGARGGNGARACNAGYAARGAR ACNGTNGARGARAAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CAYCCNGAYGGNAARGAYATGCARATHAAYYTNACNGGNTTYYTNAAY GGNAARAAYGCNMGNATHTTYGTNGCNGARYTNTGGGARCAYYTNTGYAGYGCNCARGAR AAYATHACNGGNATHCCNAAYGARTTYYTNGARCARAARAARAAYGARATHAARCARMGN CARGARGARCARGARMGNYTNCARGARCARYTNAARAARAARGARGARCARATHAARGAR CARYTNTCNMGNGARMGNAARGARATHGARAARAARACNYTNAAYAAYYTNTCNCCNGAY MGNCCNAAR---------------AGYGARAGYAAYGGNGTNAARCCNGGNGAYGGNGGN GAYGARGAYGAYTCNAARACNGARGARGCNAAR---------TCNGARCCNAARGARGAR ACNGCNGCNGARGGNGARCCNGAYTCNACNACNGARGTNAARAARGARTCNAAR---GAR AARGARAARACNCCNGARAARAARAARGARCAYMGNGAY--------------------- ------------AARGAYMGNMGNMGNCAYTCNMGNACNCCNGAYAARCAYMGN---GCN MGNTCNAARAGYCCNGAYMGN---MGNGARAGYCCNGARMGNGAYMGNCCNAGYTTYAAY MGNAGYMGNTAYTCNCCN------------------------CCNMGNMGNMGNTCNMGN TCNCCNMGNMGNMGNTCNCCN------------------CCNCCNCCNMGNMGNMGNAGY CCNCCNCCNMGNTCNGCNACNCCNCCNCCNMGNMGN------MGNTCNCCNAARAARGCN GARGCNAARMGNGAY------------MGNTCNAGYTCNGAR------AGYAGYTCNAGY GGNTCNGAYGARAAR------TCNGCNAARGARGGNTCNTCNCCNGARAARGGNGGNGTN CARCARMGNMGNAAYTAYMGNAARCAYGAYGAY---AGYGGNAARGARTCNAGYTCNGAY TCNTCNGAYGGNGGNAARGARMGNAARMGNCCNCCNCCNTCNTTYAARGAYMGNMGN--- ---------------------ATHAAYMGNAGYCCNTCNCCNMGNMGNMGNMGNAGYCCN CCNAAYMGNMGNCCNAGYCCNMGNMGNYTNAGYCCNCCNMGNTGGMGNTTYCCNTCNCCN CCNMGNMGNMGNATGAGYCCNATHCAYCAYMGNMGNAGYCCNTCNCCNMGNMGNMGNTCN CCNCCNMGNCAYTCNCCNCCNMGNMGNMGNAGYCCNCCNCCNCCNCCNMGNMGNMGNATG TCNATHTCNCCNMGNMGNMGNMGNAGYTCNGGNCCNMGNMGNCCNATHTCNCCN---CCN MGNMGNGGN---MGNMGNCCNTCNTCNMGNTCNCCNTCNGGNTCNCCNGTNAARMGNMGN ------------CCNATHTCNCCNCCNCCNMGNACNAARAARAARAARGCNGCNCCNCCN CCNCCNCARTCNGAYTCNGAYGGNAGYTCNAGYTCNGARGARTCNTCNTCNTCNCCNCCN CCN---------CCNGCNAARAARGCNCCNCCNCCNTCNAARMGNATHCCNCCNGCNAAR CCNGCNAARCCNGTNAGYGARAGY------------------------------TCNTCN TCNTCNGAYTCNGARGARAGYGGNGARTCNGCNTCNGARAAYGARTCN------------ CCNAARAARCARTGGMGNGARGCNACNCCNCCNMGNCAYGTNAAR---CCNTCNCAR--- ------------AARCARMGNCARTCNTCNTCNGCNGAYAAYAAR---AARAARCCNTCN ---------------------MGNAGYTCNMGNTCNCCNTCNMGNTCNMGNMGNGAYATH AARCCNAGYCCNCCNCCNCARMGNAARMGNMGNAGYTCNMGNTCNCCNCCNCCNMGNTCN CCNCCNAARCARCCNMGNMGNCARMGNAARGAYACNGAYTCNTCN---GAYCARGARGCN ATHAARMGNGAYMGNMGNCCNMGNGAYGTNTCNAGYCCNCCNMGNAARMGNCCNGCNMGN ---------------TCNCCNTCNCCNMGNMGNGAYMGNAAYAGYGGNAAYMGNAGYGCN AARMGNCARTCNACNCCNCCNTCNAGYGAYAARTCNMGNGARMGNGTNAAYMGNAARCAR CARATHAAYGARAARMGNGCNTCNTCNTCNGARAGYAGYAGYAGYGGNAGYAGYTCNGGN GARGAR------------------------------------------------------ AARGTNGCNAARAGYAARCCNAARGCNGCNYTNAARCCN---CCNGTNGAYAGYAAYMGN TCNGGNMGNMGNTCN------TCNCCNACNCCNACNTCNAAR------------------ ---------MGNAGYCCNTCNYTNAGYCARTCNCCNCCNCCNCAYACNTCNAARGTNATG AARCARGAYGTNMGNGAYGARGARAARGTNMGNAARMGNCCNAGYAARGGNCCNCAYGAR ------------AARGAYGGNTCNCCNCCNMGNAAYGGNAAR------------------ ------------------------------------------------------GTNCCN ACNTCNGCNAARYTNTCNAARAARGAYAARCCNGCNCARTCNGCNAGYAAYAGYGARTCN GARTCNAAYTCNGAYGAY---GGNTCNAARAARAARAARAARAARAARGARAARAARCAY AARAARCAYAARAARCAYAARAARCAYAARCAYAARAARGARGTNCCN---------GAR AARGGNGARGAYYTNGARATGMGNYTNMGNGARAARGCNYTNATGTCNYTN------YTN CAYMGNAARAARCARTCNTCNGARGCNCCNGAYAGY------AGYGGNAGYAGYAGYGAR GARGARACN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGGTNCAYYTNYTNAARCCNGARGTNTCNTCNATGTTYGCN GAYAARTGYGCNGTNYTNYTNGARACNGCNYTNTTYATGYTNCAYYTNAARAARACNGAY GTNCARGARTTYTAYAARMGNGTNTCNGGNATGGCNYTNAGYGCNGGNTGYAARCCNGTN GARGARGTNGAYGAYYTNCARGAYTCNTAYGCNACNTTYTAYTTYGARMGN--------- ------------------------------------------------CCNYTNTTYYTN TAYYTNCCNTTYCARGCNGTNCAYAGYGGNATGGAYGGNACNCAYYTNGARGCNCCNCAR GCNTAYATHGAYAARTTYAARTAYATHGARAAYAARCARMGNMGNATHTAYGCNGCNATG GTNTCNGCNYTNGAYGAYGCNGTNGGNGARATHTAYAAYACNYTNAAYGCNACNGGNYTN YTNTCNAAYTCNATHATHGTNTTYACNACNGAYAAYGGNGGNCCNGCNAAYGGNTTYGAY GGNAAYGCNGCNAGYAAYTTYCCNYTNMGNGGNGTNAARGCNACNYTNTGGGARGGNGGN YTNMGNGGNGTNGGNYTNGTNCAYAGYCCNYTNYTNAARCARAARGGNTAYGTNGCNAAY CARATGYTNCAYGTNTGYGAYTGGYTNCCNACNYTNTAYAGYGCNGCNGGNGGNAAYGCN TCNGCNYTNAARAAYYTNGAYGGNTAYGAYTCNTGGAAYATGYTNAGYAAYAAYGGNCCN GCNATHMGNGAYGARATGYTNCAYAAYATHGAYCCNATHMGNAARATHGCNGCNATHMGN GTNGGNGAYTAYAARYTNYTNGTNGGNAARATHAAYCARAARTGGGAYGGNTGGTAYCCN CCNTGGCARYTNGAYAARGAYGARCARTTYYTNCAYTAYYTNAAYTTYACNGAYAAYTTY ATGGARACNAARGARAARAGYATHYTNMGNCARGARYTNAAYTCNCARTAYCAYACNCAR TGGCAYYTNGAYGTNCAYGARMGNYTNCAYGTNYTNTAYTCNGARTCNAGYAAYAAYATH GCNTCNAGYACNCAYCARCAYGAYYTNYTNGTNGGNAAYAARGGNTCNCCNGTNAARATH GARTGYGGNCCNAARCCNGCNAAYGCNAGYACNAAYTGYCARCCNMGNGTNTTYCCNTGY YTNTAYAARATHTCNGARGAYCCNTGYGARTAYAAYAAYATHGCNAARGAYCAYYTNGAY ATHGTN---------------------------------------------GCNGTNAAR MGNCCNMGNGGNGTNTCNYTNGARAARGCNTCNTTYTAYCARGAYCCNAAYGGNTTYAAY TGYYTNTCNGAYGGNAARMGNATHGAYGTNGARCAYGTNAAYGAYGAYTAYTGYGAYTGY GTNGAYGGNTCNGAYGARCCNGGNACNTCNGCNTGYTCNAAYGGNYTNTTYTAYTGYGAR AAYTCNGGNTTYMGNGGNAAYTAYGTNAARTCNTCNMGNGTNAARGAYGGNATHTGYGAY TGYTGYGAYGGNTCNGAYGARTAYGAYGAYAAYATHTCNTGYCCNAAYACNTGYGCNYTN AARTTYGARCARGARMGNGCNGARAARGARAARYTNMGNYTNAGYCARGARGARGGNTAY AARGTNAARCARGARTAYATGCARCARGGNAARMGNGCNAARGAYGARAARYTNTCNAAR YTNAGYGARYTNGARAGYGARAARGARGTNYTNACNMGNGARAARGARACNGCNGARGCN GCNAARACNGCNGCNGARGARCCNGARAARGCNGCNATHGAYGARCAYAARAARGCNTGG GARYTNGTNAARGARGARMGNAARAARGTNCARGARGCNGARTCNGCNAGYAARGCNTTY GCNACNYTNGAYATHAAYGGNGAYGGNAARGTNGAYTAYCCNGARYTNATGAARCAYAAR GARTTYGAYATHGAYTCNGAYGGNACNGTNAGYGAYGARGARGCNAARGARTAYYTNGAR GARTAYGARGARGTNGAYYTNGCNATHTTYACNGARAARATHTGGCCNAAYATHAARGAR ATHTAYAARAAYCCNGARCARGGNGARGARGARCCNAARGGNGAYAGYGARGARCCNGCN CCNGCNGTNGCNGARGAR---------------GARGARAARGAYCCN---YTNGAYGAY AAYGCNTCNGAYGAY--------------------------------------------- ------------------GAYAARGARCCNGAYTAYAAYGAYGARACNAARGCNYTNATH GCNGCNGCNGAYGCNGARMGNAAYAARTTYAAYGARGCNGARAARAARYTNCARGAYAAY GARMGNGARATHAGYGAYATHAARAARTAYYTNGARATHGAYTTYGGNCCNAAYGARGAR TTYGCNGCNYTNAARGGNCARTGYTTYGARTAYACNGAYMGNGARTAYACNTAYMGNYTN TGYCCNTTYGAYAARAGYACNCARAARAGYAARAAYGGNGGNATGGARACNTCNYTNGGN ACNTGGGGNAARTGGCAYGGNCCNGAYGARGAYAARTAYGAYACNATGAARTAYGARAAY GGNCARGGNTGYTGGAAYGGNCCNTCNMGNTCNACNCAYGTNAAYYTNCAYTGYGGNTCN GTNAAYGCNGTNACNAGYGCNTCNGARCCNAGYMGNTGYGARTAYCARTTYGARTTYACN ACNCCNGCNMGNTGYGARCCNCCNAARTCNGARGAYATGAARGAYGTNCAYGAYGARYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TCNTCNAARYTNGAYYTNMGNAAR TCNTCNTGGYTNAAYGGNTTYATGATGTAYAGYMGNGTNCAYMGNMGNAARTTYATHMGN GAYAAYCCNGGNGTNCAYACNGCNCAYATHAGYAARATGATGGGNCARGCNTGGMGNCAR ATGTCNAAYGARCARCARCAYYTNTAYAARGARCAYGCNAARYTNTGYTCNCARGARYTN CARCAYGTNYTNGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CARTAYATHTCNGTNYTNTTYATHGCNTGGTTYATGGGNTTY GGNATHGGNATHATHTTYACNTTYYTNTTYTGGCAYYTNCARGAYYTNGGNGGNTCNCCN ACNYTNTTYGGNGTNGCNTCNGTNATHAAYCAYATHTCNGARYTNYTNGCNTAYTTYATG ACNGGNAAYTTYATHGCNAARTAYGGNCAYGTNAARYTNYTNTAYGCNGGNYTNGTNGGN AAYATHTTYMGNTTYATGTAYATHTCNYTNYTNAARAAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CCNTCNGCNACNGAYAGYATGAARYTNYTNGARAARAAYAARACNGAY GAYCARAARMGNGTNATHTCNCCNTCNAAYATHATHYTNTCNTCNAARGAYGAYAAYGCN AAYYTNGTNGAYGAYAARGAYYTNAGYGAYGGNCAYATHCAYTAYTTYTAYCARGGNGAY ATHTAYAGYYTNCCNGARAAR------------GAYGCNGAYGARACNGGNCARAAYCCN ATHYTNTCNMGNYTNAARGARATGGTNATHGARAARTCNMGNAGYGGNAGYACNAARTCN CARACNTCNMGNGAYGCNGAYYTNGGNAARTCNACNTCNTCNTCNTTYGTNAAYGARAAY CARGGNGAYGTNTCNYTNCCNGGNTTYGGNTCNGCNGCNACNCARGGNYTNGTNAARCAY MGNGAYAAYATHTCNATHGGNATHACNGAYGCNGCNAGY--------------------- ------------GARGAYATGAAYAGYGCNGGNAARMGNATHACNGAYTCNGCNTTYGAR TTYYTNAAYACNTAYYTNTCNGAYGARGARGGN---GAYGGNCARGTNGAYAGYCCNCCN ATHTCNCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TCNMGNGCNGCNTCNCCN GCNTGGAGYGARAGYAGYGGNAAYACNAGYGCNAGYAGY---------GTNTCNGGNCCN TCNTCNGTNAARYTNAGYAAYGGNAAYATHATHCCNMGNCAYAARMGNCCNTCNCAYMGN MGNGCNGARGTNAARMGNMGNGAYAARATHAARACNTGYYTNGAYGAYATHAARGARCAY ATHCCNTCNYTNCARAARAARGGNAARYTNAGYGARTCNGCNATHYTNTTYAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYTAYYTNCARCAYTAYCARTGGTAYGGN TAYYTNACNCCNATGACNTCNATGTGGCCNATHTCNAAYGTNTAYYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GCNATG TGGGAYYTNTCNAARATHGTNYTNTTYYTNYTNTTYATHTTYATHATHGTNATGGCNTTY GGNGAYGCNTAYAGYATHTCNTCNACNAAYCARYTNYTNGCNACNGTNGTNGGNGGNATH GTNCCNTTYTTYGTNMGNAAYTTYTTYAARTCNAAYACNTGYGTNGCNGGNTTYGAYACN ACNAGYGTNCARTTYAARACNGARTTYCAYACNGCNATHAAYCARTTYGARCARGCNTGG CCNGTNTAYGAYATHATHCCNGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GARATHATHCARGCNGCNATHACNAAR CARAARGARGARAAYGARAARGCNYTNACNGAYYTNGTNACNCARGGNGGNGARGARCAR GAYGGNCARCCNAARGCNYTNACNGGNGARGARGGNAARAGYGAYGARGTNGCNGTNGCN AGYGARTCNGTNATHGARAARGTNGGNACNAARTTYAGYCAYCCNACNYTNACNTTYAAR GCNAARCCNCCNGCNAAYMGNTTYCCNCCNGCNAAYCCNTCNTCNAGYATHGGNTCNGCN GTNTCNAARGTNGAYCARGGNGAYGTNYTNGGNACNGGNGTNAAYCAYGTNYTNAGYGCN GCNCAYYTNGARTCNMGNGARGCNATGTTYAAYCAYMGNTAYGAYGAYYTNYTNAARTTY CAYAGYACNGARGARGARGARGTNCCNATHTCNGTNACNTTYCAYTTYGCNAAYACNAGY MGNATGATHCCNTCNGGNATGGARCCNTCNATHCCNGCNAAYAARCCNGTNACNGTNATH YTNTGGTGGTCNGGNACNCARCAYGTNTGYCAYTAYTCNYTNYTNAAR---ACNGGNAAR GAYYTNGARATGAARCCNGAYATHGTNTGGCCNTGYTCNGAYGTNATHACNTGYTCNAAY YTNAGYCCNTGYGGNTCNCAYYTNGTNGTNGGNYTNGCNAAYGGNAAYYTNACNYTNTGG GAYTAYCARATGGGNYTNCCNAARGCNGTNYTNAAYGTNTCNAGYAARTGYGGNGTNAAR GAYYTNMGNTTYYTNGAYCCNAGYYTNTTYCCNTCNGAYCCNCCNCAYTAYCCNCCNTAY CCNGTNTCNGCNGCNACNTTYATHYTNGCNGARGCNTTYGAYGGNACNCARGCNYTNTTY GAYACNTGYGAYGGNAGYCARCARATHCCNMGNTCNATHGCNACNATHCCNGARAAYGAY GAYGAYATHCARACNYTNYTNAARGTNATHCCNGAYYTNCCNGARYTNATGYTNTAYGTN AARAARAARGGNAAYATGTAYATHAARGAYATHGGNACNGGNAARTCNYTNTGYCARATH YTNGTNCCNCCNACNCAYAGYATHCARACNCCNTGGAAYCCNATHTTYGCNYTNGGNGCN CARGGNCARGTNYTNTAYYTNAARGCNGARGGNCARGAYGTNAGYGARGARGGNGARGTN AGYGAYATHTCNTGYYTNTAYAARTAYAAYYTNMGNGAYTAYTCNYTNYTNGARGARTAY TGGGCNMGNCCNMGNGTNCARTCNGAYYTNATHGTNTAYACNACNTGYCARCARMGNATH GAYACNYTNATGAARGARMGNYTNCARCARCARGCNYTNMGNAARCCNMGNATGCARAAR CAYTGGGGNCARYTNMGNGGNGARYTNGAYATHATHCARAAYGCNMGNGARATHCCNATH GAYACNYTNMGNYTNTCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNCCNGCNTAYGCNACNCCNCCNGCNTGYYTN CAYMGNGTNGGNYTNGARTCNAGYTCNACNGGNTCNTCNTTYCCNGCNGAYTTYACNAAR CCNGTNCCNYTNGCNGTNGTNTCNCCNGAYGGNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GCNATHTGYACNGGNAAYGAY YTNACNGAYGCNGARYTNGCNGCNAARYTNGCNGARGARGARYTNACNGGNGAYCCNAAY GAYGARYTNATHGCNCARATGYTNCARMGNGARTTYGAYAARGARTAYGAYGCNGCNGTN TCNAARAARGARCARAARTAYAAYGGNAAYAGYAARGTNTAYATHTCNTTYGARAAYTAY AAR---------MGNMGNAAYCARGARGARTCNCARGAYATHGARGAYGAYGAYGAYGAY GARYTNYTNGARGGNCCNGARTAYCCNACNCCNTCNCAYTGGGARCAYGGNCCNACNACN ATHGGNAAYMGNGGNTAYAGYGGNCARGGNAARAAYATHGTNACNAARCAYGAYAARAAY ATHTGYGGNMGNMGNAAYGCNGARMGNYTNATGGARTTYCCNCCNGAYTTYGGNTGYGGN GAYGGNGARGGNATGAAYATGMGNYTNCCNAAYCARGTNTAYAAYAARYTNAARYTNCAY TCNCARTCNGAYAAYAARMGNGCNAAYAARGTNCAYGARAARAARGAYCAYTCNACNGCN ATHAARGCNGTNGAYGARAARACNMGNATHYTNATHTTYAARATGATHAAYTCNGARTTY YTNTCNTCNGTNGAYGGNGTNGTNAGYGARGGNAARGARGCNGTNGTNTTYAARGCNACN GGNGGNMGNAARGAYGAYGTNGARYTNCCNAARGAYGTNATHATHAARGTNTAYAARACN TCNATGAGYGARTTYAARAAYMGNYTNAARTAYATHAGYGGNGAYTTYMGNYTNTCNAAR GAYGCNTTYAARAARTAYAAYCCNMGNAARYTNATGAARATHTGGGCNGARAARGARTGY YTNAAYYTNAARAARATGMGNMGNAARAAYATHYTNTGYCCNACNGTNYTNAAYYTNAAR AARCAYATHYTNGCNATGACNTGYATHGGNGGNGARACNCCNGCNCCNAARATHMGNAAY ATHAARYTNAGYCCNGARGAYYTNCARGAYGCNTAYGARCARACNGTNGARYTNATGAAR ATGATGTAYCAYAARTGYAAYYTNGTNCAYGCNGAYYTNAGYGCNTAYAAYYTNYTNTGG CAYGARGARAARGTNTGGGTNATHGAYGTNGGNCARGCNGTNGAYMGNGAYAAYGCNAAY TCNGCNACNTTYYTNYTNMGNGAYTGYAARAAYATHACNGGNTAYTTYAARCARGCNGGN GTNCAYGGNGTNTCNACNGCNGARGGNYTNTTYAAYGARGTNACNAAYTAYATHYTNCAR GGNGARGGNAARGTNTTYGARTCNCARGTNCAYMGNTAYGCNAARGARGARTAYGCNTTY GAYTTYTTYTTYGARATGACNGARTCNTCNMGNYTNCARMGNYTNGAYGTNGAYAGYAGY GGNGARAGYGARGARGAR------------GAYGGNGGNGARGAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CAYMGNGAYYTNGTN GCNAAYMGNATHTCNTCNGCNGAYGTNAGYCARGTNTAYGGNCCNACNGGNTCNGAYTAY YTNTTYATHGCNYTNGGNGGNGARTTYCAYTGYGTNTCNYTNAAYACNGGNTGYGGNGTN YTNGCNATHGAYAAYCCNGCNMGNCCNMGNGTNCCNTCNTTYMGNGGNYTNGTNATHGAY GARAARCARTTYGGNYTNTCNMGNACNCARAARGTNTCNTTYGTNGGNAAYATGGGNTCN YTNTAYATHATHATHTAYGAYCARAAYTCNACNGGNYTNAARATHYTNMGNYTNGARGAY GGNAAYAGYCAYGARGAYTCNGTNATGGTNTGGAARGCNTTYCARCARTGGGARMGNTAY GARGCNACNCCNATHGARATGMGNATHAAYCCNGTNGAYTGGGCNYTNCCNGAYATGAAR CAYAARCAYGCNGARATGMGNAGYYTNGTNYTNTCNYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNYTNAGYGARGCNGAYAARACNGCNATHGARAARATHATHGCNGAYMGNGAY AARGARGCNTCNCAYAAYATHAARGCNCCNGAYGAYAARGAYYTNMGNACNAARATHCAY YTNGCNGTNAARCARAGYTTYTCNCARYTNGARACNAARACNATHGARGAYAARCARGGN AAYAARGTNATHCARGTNACNTGGMGNAARGGNAARAGYMGNGAYACNAAYMGNGAYGAR TGGCCNAARTCNAARAARTCNTGYMGNTAYGTNMGNTTYGTNYTNTAYAARGARAAYAAR GAYACNATGGAYGCNATHGGNYTNATHGCNAARAAYYTNAARGTNMGNGARAGYATGTTY CARTAYGCNGGNACNAARGAYAARMGNGCNAARACNACNCARGARATHACNGCNCAYMGN GTNCAYCCNAARAARYTNGTNGGNYTNAAYAARGTNYTNTGGAAYATGGGNYTNGGNAAY TTYMGNTAYGTNCARCARCCNYTNCARYTNGGNCARYTNTCNGGNAAYMGNTTYGTNATH GTNYTNMGNAAYGTNMGNGGNAGYMGNGARGTNGTNGAYACNGCNYTNACNTCNYTNAAR GAYAAYGGNTTYATHAAYTAYTTYGGNATGCARMGNTTYGGNACNACNTCNATHCCNACN CAYAARATHGGNAGYGCNYTNYTNCARTGGGAYTGGGARAARGCNATHGAYYTNATHYTN GCNCCNMGNAAYGAYGTNCCNGCNAARGAYAARTTYCARAARATGTGGGCNAARACNMGN GAYCCNTCNGCNACNYTNGARGTNACNCCNMGNTTYTGYGGNYTNGARMGNAAYATHYTN GAYGCNYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGAAY CCNAGYMGNTCNYTNGGNTCNGCNGTNGCNTCNGARTCNTGGGAYGAYCAYTGGATHTAY TGGGTNGCNCCNATHGCNGGNGGNGTNYTNGCNTCNGTNGTNTAYAARTTYGTNYTNAAY CCNTAYMGNGGNATHATHAAYATGGAYGARGCNGTNAAYAARYTNAAYGGNGCNGARGAY TTYGTNGTNATHCCNMGNGAYTAYTTYAARGAYAAYYTNAARGCNGTNGAYACNCAYATG ---------------------------AARATGGCNGARGARYTNCCNYTNTTYCCNAAR GCNTCNTCNATGTAYYTNCAYAGYGGNAAYATGATHAAYTGGAAYAGYYTNAARMGNAAR CCNAAYYTNTCNTCNTCNGAYGARYTNTAYGARGTNYTNACNGCNACNYTNGGNTCNTAY YTNTCNGARGCNGAYAARACNGARYTNCARTAYGTNACNGARGTNTAYAARACNAAYGCN GARAAYGTNGARYTNATHGAYGARAAYGARMGNGGNGAYATHAARGTNACNGTNAARATH TTYATHTGYGAYTCNCARTCNACNAGYGCNATHGGNGAYGCNGTNAAYMGNGTNYTNAAY GARYTNGGNACNCCNTTYGTNGARACNYTNYTNYTNGCNGTNAGYCCNAAYTGGGGNGAR GARCARGAYACNGARCCNGTNGTNAGYYTNGCNTCNATHCARAARTAYTGGCAYGCNATG GARGARYTNGTNGCNAARGAYAARGTNYTNTCNYTNGGNGTNTGYGAYYTNGGNAARGAR GGNYTNGARACNYTNTAYAAYTGGGCNCARGTNAARCCNTGYGTNAAYCARGTNAAYYTN GARTCNTGYTGYGTNYTNCCNAARGAYYTNACNGARTAYGCNAARGCNATHAAYGTNCAR YTNYTNACNCAYAAYGAYAGYCCNGCNTTYATHACNAARGAYYTNYTNCARGARAARATH CARAGYGTNTCNACNGARMGNGAYAGYGAYGCNTGGGTNCCNGARTGGGTNGCNMGNTAY TCNGGNATHYTNAARTGYMGNGGNATHATHAARATGAARGGNTAYGTNTTYCAYGCNACN MGNGAYAAYAARAARMGNATHYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CCNGGN------ ------------------------------TCNTCNCCNYTNYTNACNMGNCCNCCN--- ---ATGCARTCNACNGGNCCNCARATHAAYCCNATGGGNMGNYTNCCNATGCCNYTNATG TCNACNCCNGTNCAYCCNCCNCCNGGNATGCARGCNCCNCCNGGNYTNATHCAYCCNCCN GGNCAR------CARCCNCCNCARCARYTNGGNACNATHCARCARCCNCCN--------- ---------------CCNCARCARCARCARCARCARAAYCCN------------------ CARCAR------CARCARGCNYTNMGNCCNTGGCARCARGCNGCNAGYCARTCNCARCCN YTNATGAAYATGAAYCARGGNGCNTCNAGYTCNAGYATGGGNATHCCNCCNCCNCCNCCN TCNATGATGAGYCCNCCNCCNCCNCCNCCNGCNAGYACNCARGGNCAR---GTN---CAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TCNCCNATHTGYTCNAGYYTNTCNACNGTNATGAGYGTNTCNTCNTCN TCNYTNATGYTNTCNTCNGCNGCNGCNACNYTNGCNCCNGTNTCNAAYAARGTNGTNYTN MGNAARGAYAARAAYAARMGNGTNYTNGAYMGNCCNAAYAGYATHGCNTTYTCNTCNTAY CCNATHTGYGAYYTNAGYCCNAARGCNAAYGARGCNAAYGGNGCNATHCCNAGYCAYCAY GAYGAYTCNAGYAGYGGNAGYGCNCAYGGNYTNGCNMGNMGNTCNMGNTCNTCNYTNAGY CCNGAYGTNCCNTAYCAYMGNGGNMGNACNTCNTGGAGYTGYTAYTCNGARMGNGARGTN TAYMGNCARATHACNGCNGCNATGGARAGYGCNATGYTNMGNACNCARGTNTAYYTNCCN CAYCARTCNCCNAAYTCNGGNGGNMGNAAYACNGAYTCNGGNGCNTCNTCNMGNAARGCN MGNAGYYTNGAYAAYATHATHGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNCARTAYATHAAYYTNTAYAARACNGTNTGGTGGYTNCCNCAR TCNCAYGCNCARTAYGCNYTNAAYTTYTAYYTNATHGAYTTYAAYYTNGCNTTYYTNATH TGYGTNATHYTNGCNGTNMGNTTYYTNATHTGYTTYATGCARGARGTNCAYAGYAAYMGN ATHYTNTAYTGGCCNYTNTTYTGYYTNAARATHTTYATGGTNGCNTTYGCNGTNGTNGTN YTNGTNTAYACNGGNTAYAARGTNATHATGGARCAYGGNGTNGTNACNAGYYTNTTYYTN TGYTAYCCNGCNGTNATHTAYYTNGTNYTNTTYGGNYTNGCNATHAARCCNYTNTAYCAR MGNCAYCARGCNTGGCCNMGNCCNGCNTAYGGNYTNGAYMGNCCNGCNGGNCCNATGMGN ATHAARATGAARGAYGAYGCNCCNYTNTGYCAYACNTGYACNYTNACNCCNGAYATHGTN MGNGARGARGTNGAYATHYTNAARMGNGAYTTYAAYAGYMGNYTNAARCARATHYTNTTY AAYTCNYTNACNACNTCNTTY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ACNGTN GAYGCNGARACNGCNGTNGTNYTNGAYAAYATGAAYCCNGAYGTNTAYTGYATHMGNGCN YTNGTNMGNAGYTGYMGNAAYGARGAYAARYTNGCNYTNAARGAYYTNGAYTAYGCNYTN ACNTTYAGYCCNAAYCAYGTNGCNTGYYTNGTNGTNMGNGGNGCNATHACNMGNCCNTGG TCNCCNAARTTYCCNGGNGAYATHCCNMGNCARAAYAARTAYYTNMGNAARGCNGARMGN YTNAAYCCNGAYTCNCARTCNTAYTTYAAYGTNGAYAGYTTYAAYCAYCCNTAYGTNYTN GAYTTYTAYGAYMGNATGYTNTTYACNYTNYTNGTNCCNCAYACNATGACNGARATHAAY YTNAAYCCNGAYAARCCNAGYAARAARCARYTNGARTCNAGYCCNGARYTNTCNMGNCCN GARTCNTCN------------------------TCNAGYTCNMGNGTNGGNTCN---ACN GARMGNYTNGAYCCNTTYMGNTGYGGNACNCCNTCNGTNAGYGAYAARGGNTGYTCNACN MGNMGNMGNYTNGAYTAYGGNGARGCNGTNMGNAARCAYAAYTCNMGNCCNAARACNGCN TCNGARTAYATGGCNGTNYTNGARAARGARMGNMGNYTNMGNYTNGARGCNTCNACNMGN ATHCARTCNGCNMGNAAYGTNMGNTTYGCNGCNTCNACNGAYMGNTGYCARTCNGCNAAY CCNAARTCNAGYCARTCNTCNTCNAGYGGNMGNGTNACNAARACNMGNCCNACNAARGCN TTYGTNTTYGARACNCCNAARAAYTAYTCNATHCCNGTNTTYCARCCNATGAAYATHGCN GARGCNCCNMGNATGTAYTAYMGNCCNTGGMGNGGNGAYAARYTNCCNATHGGNGARGTN CCNCAYCCNCARCCNGCNCCNGCNTTYTAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GGNGARTTYCCNGTNCARGAYYTNAARACNAARGARGGNGGNYTN YTNCARGTNTGYATGGARGGNATHGGNYTNYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GCNGAYCCNGAYYTNGAY YTNGTNTTYTCNCCNGGNYTNATHGGNTCNCCNGTNGTNGCNTAYGARCARGGNATHAGY GTNTCNGAYATGAARAARGCNGTNACNTGYYTNACNGARYTNTAYACNYTNGGNGGNTAY AARGAYGGNAARYTNCARAAYACNGAYGGNGTNAARATHGARGARAAYGARYTNGGNTGY MGNTAYATHTCNGAYTAYMGNCCNTCNTCNTCNACNAARAARCARGAYTGYMGNGARGTN GCNTGYATGGCNGCNGARTTYGGNGGNTGYAAYGCNATHTAYCCNTTYYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYAARTGGTAYMGNGTNAARGCNGGNYTNTTYYTNGCN TCNGTNACNGGNTGYTCNATHYTNGCNGGNTTYGGNYTNACNGTNGGNATGGCNAARAAR AGYGAYCCNAGYAAYTTYGCNAARGGNYTNGGNGGNTCNAARGARYTNCCNGARAGYGGN GTNGCNYTNGCNACNMGNGCNYTNACNMGNGCNTCNYTNTAYTCNGTNACNGGNTTYGGN ATHTTYTGYTTYGCNGTNTGGAARATGATGGGNGTNCAYAGYATGGTNGARTTYMGNGAR AARGTNGGNAAYGCNYTNCCNMGNYTNAARMGNAARGARAGYACNGGNMGNAAYGARTTY GCNACNATHMGNGAYYTNTTYGARTAYATHATHGCNGARGAYGARAARGCNAARGGNMGN AARATGGARAARGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARGAYGCN GARYTNYTNGARYTNMGNAARCARATHCAYGGNYTNTCNAARGAYYTNACNGAYGCN--- ---------MGNAARYTNCARCARGARAAYAGYACNGTNGARATHYTNAARCARCARATH CARGTNTGYACNGARGAYTTYAAYACNGARMGNMGNGAYMGNGARCARGCNGTNCARAAR GCNMGNGCNYTNCARGAYGARAAYGAYAARATHAARGCNGARAAYAAYAAYYTNAARAAR CARATHGAYGGNYTNAARMGNATHGCNGARCARCAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AGYGGNYTNCARTGYCAY AAYTGY---------CARTAYGTNACNTGYGGNGAYAARTAY------------AGYAAY GAYCCNGCNAAYYTNGCNGAYTGYGAYGAYGGNTCNTAYTGYGTNAARTAYAARACNATH TCNTGGATHCAYGAYTCNGGNGARATHACNGGNTCNYTNAARGARTCNCAYGTNGTNTCN MGNGCNTGYGARTCNAARAARGGNAARAARGARGGNTGYATHGGNTGGCARAAYAAYGGN GGNGTNACNYTNAARTGYTGGTGYGGNACNGAYGGNTGYAAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARAGYAARTCNGCNGGNAARAARACNATHCCNCCNYTNATGYTNGAYTCN YTNGGNMGNCCNATGATHCCNATGATGYTNGGNGAYATHACNYTNCAYAGYATGGGNGAR ATHGTNACNGAYAARTCNGGNTTYCAYTGYGCNGARGCNATHTTYCCNGCNGGNTAYTGY ATHACNMGNGTNTAYGTNAGYYTNCAYAARCCNGAYGCNAARTGYYTNTAYACNTGYAAR ATHTCNGARGGNGAYCAYGGNCCNYTNTTYGARYTNGCNCCNGARGAYAGYTCNGAYATH GTNTTYMGNGCNAGYAAYCCNTCNGARTGYCAYAGYYTNYTNYTNCARGCNGTNAAYAAR TCNMGNGGNGCNGARGTNYTNCCNACNGARACNACNGGNYTNGAYTTYTTYGGNYTNTCN CAYTCNGTNATHCARAAYYTNATHCARTCNATHCCNGGNGCNMGNAARTGYTCNMGNTAY AARTGGGTNAARTTYGARATHGAYAARACNGARTCNAAYGARAAYTTYGCNATHGGNAAR ACNGAYCCNACNATHAGYTAYGARGCNTTYATGAARCAYYTNTCNAAYYTNGGNCARGGN MGNTCNGGN---YTNGCNTCNCARACNGARAARTCNACNAGYYTNMGNTCNYTNYTNACN AAR---------ATGAAYTTYAGYATHGARYTNGTNYTNGCNTCNGGNGGNMGNATHGGN AAYATHACNCARATGGTNCARGGNMGNACNGTNTCNYTNAAYACNCCNATGTGYTCNYTN TTYACNAARGGNGGNAGYGTNCCNTAYYTNAGYYTNAGYATGYTNGAYAARATHTCNMGN GTNCCNCARYTNGCNACNATGAGYGTNAAYTCNTTYGTNGAYCAYTAYGARAGYATHAAR GARAAYGGNAARGGNYTNGTNGGNTTYACNTCNATGAARGAYMGNYTNGTNTTYTCNACN YTNCAYGAYGCNAGYYTNCCNGTNCCNTCNGGNAARAAYGAYAARTTYGGNGTNGCNGTN TGGGGNAARGGNGGNAARACNAARYTNGAYCCNAGYCARTAYATGAARATHCARGARGCN YTNAARCCNGAYTGGATHYTNGCNYTNGGNGAYGCNGAYACNGAYCARGARAGYGGNGAR AARMGNGCNGGNAARGCNGTNGAYMGNACNYTNGAYTTYYTNGAYGAYGTNGTNACNGAR TGGGARAARAGYGARAAYYTNAARACNTGYAGYYTNATHGGNGTNATHGTNGGNGGNTAY AGYGARAARCARMGNGARMGNAGYGCNAARGARACNTCNTCNMGNCCNGTNAAYGGNTTY YTNYTNGGNGGNTTYCARAARGGNAAYACNCARGARAAYGTNTTYGAYAGYGAYTCNTTY ACNCAYATHYTNCARGCNACNATGGCNCAYYTNCCNGARAAYAARCCNMGNATHATGGAR AAYCCNTGGTCNCCNYTNCARGTNATHAARGCNTTYAARYTNGGNGTNGAYGTNTTYTCN AGYGCNTAYCCNCAYACNYTNACNGARCARGGNATGGCNATGATGGARGAYTTYAGYYTN CCNCCNAARTCNCCNGCNGCNGGNYTNGARGCNGARGAYTGYGAYGAYAAYAAY---TCN GTNGGNCCNGTNATGAAYYTNAARGARAARMGNTTYTTYGAYGAYTTYGGNCCNGTNYTN GAYGGNTGYAGYTGYTAYACNTGYGCNACNTTYACNMGNTCNTAYATHCAYCAYYTNYTN AAYACNTCNGARYTNYTNGCNTAYGTNYTNYTNACNATHCAYAAYTTYGARMGNTAYTTY GAYTTYTTYCAYGCNYTNMGNGARGCNGCNMGNAAYGAYMGNYTNGAYGARYTNGARAAR AARYTNTCNACNCAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGACNACNGTNTGYAGYTGGYTNAGYTTYYTNTGYATGMGNGARGTNCAYAARAARAAR GCNGTNCARCAYMGNATHCAYCCNAAYMGNCARGCNTAYGAYGCNGTNGTNGTNTGGAAY GGNAARGARAAYCARAARACNAARCARGGNAGYATHAGYTTYGAYGTNATHYTNAARCCN GCN---------TCNGCNGAYTCNCCNMGNCCNTCNYTNCCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CCNTCNATHTAYAAYTGYCAYYTNTGYTCNGCNAARYTNAGYACNGARTTYTTY YTNMGNYTNCAYYTNGCNAARCAYAAYGGNTTYMGNCAYATGTCNACNYTNTCNACNTCN GAYGGNGTNYTNATHTGYTCNAAYTGYAGYTAYATHGCNAGYAGYAAYYTNGAYYTNGCN AAYCAYGTNTCNACNCAYGTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CCNACNTCNTGYACNAAYGCNAAYGTNTCNCCN GCNATHGTNAAYAAYATHGGNGTNGGNACNACNGTNCCNTGYGTNGAYGTNGARTGYAAR GTNCAYCAYGARGARAAYTGYGAYAGYGTNGAYGAYAGYTGYTCNGARMGNAGYTCNAGY ACNTCNTCNAAYCARAARGARGGNAARTAYTGYGAYTGYTGYTAYTGYGARTTYTTYGGN CAYAAYAAYCCNCARGGNGCNAARACNAGYCCNAAYTAYTTYGARATGAARGAYMGNYTN MGNAARAARYTNAARAARAARAAYGARAAYAARCAYAAR---CCNGCNCCNGTNCAYGAR MGNCCNCARGTNGARGGNAARAARGARGARCCNGCNGARAARMGNGGNYTNGAYGARYTN YTNAGYTTYATHAAYGGNACNGAYGAYAGYAAYMGNACNACNAARGCNGCNAARMGNGCN MGNCARAARCARMGNAARYTNGARGARAARGCNMGNCARGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGGGGNGCNATGMGNTCN TCNMGNACNCARGCNATGCCNMGNCAYTCNYTNTTYGGNACNGCNYTNGARCAYGTNGAY MGNGARGGNYTNAARGAYATHGARGGNMGNTAYATHCCNGARGGNGCNGTNAARGARATH CCNAAYMGNTAYCCNYTNCCNCCNCAYATHAARGARGGNATHCCNGGNMGNGAYMGNYTN GARACNTCNMGNAARGCNTTYTCNGCNCARMGNGAYGCNYTNTCNCARGCNGAYGARAAR YTNAARTCNAARTCNGCNAARGTNTTYGCNTTYAARCCNTCNGARCAR---------CAR TGYCAYGGNGGNYTNCCNTCNAAYMGNCCNGCNTGGYTNTCNGARAARGAYYTNGARCAY TCNAARGAYATHAAYATHYTNGGNYTNTCNCAYCAYGGNAGYTAYAAYMGNGAYAARTAY GGNAARAARCCNCARGTNCAYAAYTAYAGYYTNATHGGNGAYATHYTNGCNCCNAARATG GAYTTYAAYTCNGCNMGNACNGGN------------GARGAYAARAGYAARGTNGGNACN GAY---TGYGCNTGGGGNCCNGGNMGNCAYYTNCCNTAYGAYATGATGGARCARCARAAR AAYTCNCARAARAARACNCAYTAYAARAGYGTNATHGAYYTNCCNCCNAAYATHMGNCAY CARTTYGGNAGYMGNGTNTGYGAYACNYTNYTNTCNGAYCARAAYYTNGTNTCNYTNGCN YTNGARMGNCARAARTCNAARATGGGNCCNCCNMGNCCNTCNAARAARGARAAYGTNCAR GGNYTNCCNGTNAAYYTNAGYAAYAAYTAYGARAGYYTNGGNCAYACNACNMGNTAYAAY GTNTGYCCNGGNGTNAGYTCNGGNCAYAARATHAGYMGNACNAARGAYGARTTYAAYGAY GARGTNCAYYTNAARMGNGTNCCNAAYCCNGAYGARTAYMGNTAYCARMGNGAYGARYTN AGYNNNATHTGGGTNGARCARGAYGTNYTNMGNAARMGNATGGARCAYAARTGGACNTCN TAYTTYAARCARAARCCNAARATHCARMGNAARCCN------------------------ ---------------AARCARAARCCNGARGARGTN---CCN---GTNGAYAAYGARATG GAYATHGTNTTYGTNACNCCNCCNYTNACNCCNCCNCCNCCNCARCARGARATHGTNGAR YTNCCNAARGCNTTYGARMGNGAYGAYGARTTYTGGAGYTTYTAYGAYCAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARCAYYTNGAYCCNGARCARCARAARYTNGARYTNGAYGAYACNATGAARYTNGCN TTYCARAARMGNGGNGARAARGCNTTYGTNATHAGYAAYGTNCARYTNYTNGCNCCNAAR GCNGCNYTNYTNYTNCAYGGNTTYTGYGAYGGNGAYAAYGCNCCNTAYAARGAYGTNATG ATHYTNYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYCAYYTNYTNTCNGGNCARATHGAYTAYATHAAYMGNYTNTCN MGNAARATHYTNYTNMGNATHYTNTTYAAYYTNGAYYTNGTNTCNYTNTCNAARATGGGN MGNGTNAAYMGNYTNTTYMGNGARYTNTGYACNTGYGAYACNATHTGGTCNAARATHTAY ATGGAYAAYACNAARCARCCNGTNTCNCARGARYTNYTNATGYTNGTNGAYCARAARGGN TGGMGNGARGTNTTYTTY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TTYGARGCNATHCCNTAYACN TTYTAYAARCCNGGNACNACNTAYTTYTGGGTNCAYTTYGGNYTNGTNATHTTYGGNTTY GTNATHGCNGTNGCNACNYTNATHGGNCARTGGMGNAARCCNGCNCCNTAYGGNAARCAY GARGCNTAYGARCCNAAYTGGGGNCCNYTNATHCCNCARMGNYTNGCNCAYTTYYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATHCARCCNMGN TTYGCNTCNTTYGGNACNAARYTNGCNCCNAAYMGNAARYTNGGNAAYGGNGGNTCNACN YTNYTNMGNTAYGGNMGNAGY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYAAY TTYGARMGNGGNCARACNGARGTNTTYGARYTNAAYGCNYTNGAYGTNGGNGCNATHACN MGNATHCARATHGGNCAYGAYAAYTCNGGNCCNGGNGCNGGNTGGTAYTGYGARCAYATH ACNGTNAARAARTTYYTNCAYCAYGARGAYATHGTNGCNTTYYTNAARAAYATHAARAAR AARCARAARCCNAARGARCARAARMGNAARMGNYTNTCNCARAARYTNAARGARMGNGAR YTNAARYTNMGNGAYGAYGAYAGYGAYAARGARGAYGARAGYGARGARGARAGYGAYGAY GARGAYAARGARTAYAARAAYGTNTTYGAYATHGAYGGNAARGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TGYCCNTTYTCN CAYGAYGCNTCNGARCAYAARATGCCNGTNTGYYTNTAYTAYYTNMGNGGNGTNTGYTCN MGNCARGAYTGYYTNTAYYTNCAYGTNAARGTNAAYCCNGAYGCNCCNGTNTGYCARGAY TTYYTNCAYGGNTAYTGYCCNMGNGGNMGNCARTGYAARAARYTNCAYTCNTCNGTNTGY CCNTCNTAYGCNGTNTGYGGNAARTGYCCNAAYGGNGARAARTGYTCNATGYTNCAYMGN MGNAAYAAR---ATGCCNACNTTYAARATHGARACNAAYYTNMGNAARGAYCARATHCCN GARAARTTYTGYCARGARGCNACNAAYYTNATHTCNTCNGARYTNGGNAARCCNGGNACN TAYGTNTGYGTNCARGTNTGYCCNGAYCARGTNATGAGYTTYGGNGGNACNTCNGARCCN TGYGCNAAYATHACNYTNAGYTGYATHGGNGTNGTNGGNCCNGARAARAAYMGNYTNYTN GCNCCNATHYTNTCNGAYTTYATHGARAARCARYTNGGNATHAARCARGAYMGNTTYTAY ATHAAYATHTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GGNYTNATHGARMGNACNTGYGAYYTNCAYMGNYTNACNYTNGGNYTNGCNGGNAAR GARTTYACNCCNGAYCARACNCCNGARAAYAARCCNGCNACNGCNYTNGCNTCNGGNYTN GTNAARGCNTGGGARYTNTAYAAYAAYTCNAARGCNGTNATHYTNTTYYTNATHAGYGAY AARGARMGNAAYATHYTNGAYCARMGNGCNYTNGARYTNMGNGTNTAYGARAGYAAYCCN CAYGTNMGNGTNGTNMGNAARTCNYTNYTNGAYATHTAYGARAAYGGNAGYYTNGAYAAY GAYAGYAAYYTNGTNGTNGAYGGNGAYGARGTNGCNGTNYTNTAYYTNMGNCAYGGNTAY ACNGCNGAYAAYTAYCCNTCNCARAARGARTGGGAYGCNMGNYTNAARATGGARYTNTCN MGNGCNATHAARTGYCCNTCNATHCARCAYCARYTNGCNGGNGCNAARAARATHCARCAR GARYTNGCNMGNCCNGGNGCNYTNGARMGNTTYATHGARGAYCCNAARGTNGTNAAYGAR YTNMGNGCNACNTTYGCNGAYCARTAYAGYYTNGAYYTNGGNGARCARGGNGAYAARGCN GTNGCNYTNGCNYTNGARTCNCCNCAYAARTTYGTNYTNAARCCNCARMGNGARGGNGGN GGNAAYAAYYTNTAYGGNGAYGAYATHGTNAARTTYTTYAARGARCAYGCNAAYTCNAAR GARMGNAAYGCNTAYATHYTNATGGARMGNATHTTYCCNYTNCARCARCARAAYTAYYTN TAYAARGAYGGNGTNCCNTTYGTNYTNTCNAGYGTNGTNAGYGARYTNGGNATHTAYGGN GTNTAYATHGGNTCNACNGAYATGACNGARGTNGARAAYAARGARTGYCAYCAYATGATG MGNACNAARGTNYTNGGNACNGAYGARGGNGGNATHTGYGCNGGNTTYGCNGTNYTNGAY ACNCCNYTNGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNGGNATGGTNAAYGCNATHAAY YTNGAYGGNGGNGGNTCNACNACNTCNATHATHAAYGAYACNYTNGCNGGNTTYACNAGY AAYAARTGYAAYGARATHTAYACNTGYGARMGNGAYGTNTCNACNGTNATHTGYGTNCAY TAYCCNGARTGYTCNCCNCCNGAYTGYTCNAAYCAYGGNGTNTGYAAYAARGGNAARTGY YTNTGYMGNGARCCNTGGACNGGNGAYGGNTGY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATGATHCCNATHTAYYTNATHGTNGCNGGNAGYTTY GGNTGYGCNAARAAYYTNTTYAGYYTNATHCARMGNTGYMGNAARACNGARGARGARMGN CARGARGAYCARAARAARGTNAAYCCNGTNACNAGYATHGTNGAYTGYTTYYTNTTYGCN TGGTTYATHGCNGGNTGYGTNTTYATHTAYMGNACN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY GAYCARAGYMGNCARGCNGTNTCNCAYTCNAAYTAYAAYAAYCARCAYCCNGAYACNTTY AGYGGNGGNYTNGGNCARGCNGTNAGY---------------GCNMGNACNAAYYTNCAR GARAARGARACNGAYTAYGAYGARATGGARCARTGGYTNGCNACNCAYGARGGNCARCAR TCNGAYGCNAARACNCARGARCCNATHACNAGYTCNGARTTYGAYMGNTTYYTNTCNGAR MGNGCNACNGCNTCNGAYACNGTNCCNAGYATHTCNGCNCARACNGGNMGNTCNTCNMGN ACNYTNCARAARAARGAYGARGAYGARAAYCCNYTNTTYGCNYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNAAYGCNYTNATGTAYGGNTGYGCNMGNYTNGGN GTNGAYYTNAGYGTNGCNACNCCNCCNGGNTAYGARCCNGAYGTNGAYATHACNTTYGAY GTNATGAARATHGCNGGNAARACNGGNGCNTCNTTYCARATGGGNAAYAAYCCNGTNGAR GCNGTNTAYMGNGCNGAYGCNATHATHGCNGAYGCNTGGYTNGAYACNGCNMGNACNGAY GARGGNMGNCARAARYTNGTNACNGAYTTYCARGGNTTYCARGTNAAYMGNAARATGYTN AARGARGCNGGNGGNAGYTGGGTNTTYYTNCAYCAYYTNCCNMGNAARCCNGARGARGTN ACNGAYGAYATHTTYAAYGCNGARGARTCNYTNGTNTGGCARCARGCNGARAAYTCNATG TGGACNGCNATGTCNGTNYTNYTNCAYGTNYTNGARCCNTAYGCNCCNACNATHGTNATG CCNAARTAYGTNMGNGGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TCNGAYGARCAYAAYGAYTCNGAR GAYGARACNGGNACNTGGATHCARTGYTGYATHTCNGAYTGYGGNAARTGGMGNTAYGCN GCNGAYATHCCNGAYCCNATHCARGTNCCNGARCAYTGGAAYTGYAGYATGAAYTCNGAY AARGAYCAYAAYAGYTGYGAYGCNCCNGARGCNGARTAYGAYGARAGYGARCAYATHYTN ACNAARTTYACNYTNGGNTCNGTNGTNTGGGCNAARATHGAYGGNTTYCCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHATHMGNGAYAARAARGGNTTYAAYMGN---TGGCAYCCNAARTAY GARYTNATGYTN---------AGYGGNTGYTTYMGNTTYYTNATGAAYGGNAARAARMGN CCNCAYAAYMGNACNTCNAAYTAYYTNATHACNACNNNNACNAARAARYTNAARAARAAR CARCAYGGNACNYTNGGNAARYTNMGNTCNAAYTTYYTNGGNACNNNNTTYACNATHTAY GAYNNNGGNGARAAYCCNAARAARAARYTNCCNGCNGCNATHMGNAARCARTAYGGNGTN ATHYTNTAYGARACNAAYATHYTNGGNTCNMGNGGNCCNMGNAARATGAARGTNYTNATH CCNGCNATHGAYAGYCARGGNMGNMGNGCNGTNTGGMGNCCNATGAAYGAYAARGARGGN ATGYTNCARAGYTAYAARAAYGGNGARMGNNNNYTNGTNATGACNTTYATGAAYAARCCN CCNGARTGGAARGARNNNYTNCARGCNTAYGTNYTNAAYTTYAAYGGNMGNGTNGARAAR GCNTCNGTNAARAAYTTYCARYTNATHGAYAARAAYGARCCNGAYTCNATHYTNATGCAR TTYGGNMGNGTNACNAARCAYGARTTYTCNATGGAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARATHAARGAYCARATGTTYGAYTAYYTNAAYCARYTNGAY GAYAAYYTNGTNAARGCNCARTGYTTYGCNATGYTNTTYTGYGCNTAYGARYTNTTYYTN CARTTYACNCARGAYATHYTNMGNGTNCARAARAARYTNACNGCNTCNGCNTGGTCNTCN ATHAARACNAAYYTNGCNMGNGARMGNAGYGAYGARGTNATHTCNGCNGCNATHCAYTAY ATHGTNTCNGTNAARTTYGAYGTNGAYAARTGYTCNGCNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GCNTCNGCNACNTCNTGGGARGTNGTNGGNAARAGYAAR------AARGGNAARAARGAR AGYYTNTCNGTNGCNAARGARAARGARYTNYTNGAYAARATGCCNAARATHGARAAYAAY GAYCCNGTNAARYTNGAYGARACNGTNTAYTCNGCNTTYATGCCNAARGARAARCARAAR GARAAYAAYGCNAGYGTNAARATHGAYGCNCAYGARCARAAYGGNAAYAARAARACNACN AAYCARAARAARAARAARCCNGAYCARGARCAYAARAARAARAARAARCCNGTNCCNYTN GARACNGCNYTNGCNTCNYTNAARCCNAARGAYYTNGARTTYGTNYTNAAYCARTCNCAR AGYTTYTTYCCNAAYCAYCCNGTNGTNTGGYTNAARGAYYTNGCNTCNTTYYTNAAYATG CARYTNGARGAYACNATHGAYACNGAYCCNGCNTAYAARGGNAARTCNTCNGGNTTYCCN YTNGAYGCNGTNTCNACNGTNTAYGCNACNGTNYTNCAYACNTTYATGAARAARTTYTCN AARCARACNYTNGAYGGNATHTTYTAYTAYGGNATHCARACNATGYTNCARGARYTNGCN AARGGNAAYAAYGTNCAYGGNTTYAARYTNTTYYTNCARYTNYTNGCNCAYACNAARCCN GAYATHGTNGTNGAYAARYTNCCNCARTAYYTNGARYTNYTNAARACNCAYCARAAYAAY CCNGCNAARTGYYTNTCNGTNYTNTGGGCNYTNGGNCARTGYGGNTTYAARAAYTTYAAY TGYGGNYTNAARGTNTGGYTNGAYYTNATGYTNCCNGCNYTNGARGTNMGNCARGTNGCN CAYTAYCCNGTNGARTAYYTNGARGCNYTNGTNAARTCNAAYAARAGYACNAAR---AAR ------------AGYTTYGGNYTNGTNACNYTNMGNGARTAYTTYCARGTNYTNGAYGTN TTYTTYTGYCCNAARTTYACNYTNGCNAAYGAYYTNAARAARMGNYTNACNTCNATGTAY CCNTTYATHAARACNYTNGCNTAYGGNGARGARCCNTCNCAYAAYYTNMGNACNTTYTTY CCNTCNTAYYTNGCNMGNTTYTCNTCNACNAAYTCNCARCCNYTNAARAARGARYTNYTN YTNTGYYTNACNCAYTGYYTNATHACNGAYAARCARTCNTTYAGYGTNTGGTGYCARYTN TAYACNAARCAYYTNTCNGCNTCNAGYCAYYTNYTNGAYCAYATHAAYAAYGARTGGCCN AARYTNTCNTCNAARTTYAAYAARAARATHYTNAAYGARACNYTNMGNTCNTTYTCNGTN ACNAAYGARGARYTNGARGTNCARAGYAARGGNAARCARGAYGGNYTNAARYTNTGYCAR TCNGCNACNAARAAYYTNATGGTNAARATGAAYGGNACNCAYTTYCCNTGGAGYATHYTN GTNGCNTTYYTNGTNACNGTNTTYGCNGCNATHGTNATHTAYGAYATHGTNTCNAGYCCN AGYTTYAAYTCNTCNAARACNATGCARTTYYTNGARCAYTAYGGNATHYTNGCNYTNYTN GGNAARACNTAYCARTTYATHTAYAAYGCNTTYACNYTNTCNGTNAAYTGGYTNAARGTN AAYTTYCCNATHTTYTAYGCNTAYGTNMGNGAYACNATGGGNCCNTTYYTNATHYTNGTN TGGGARTCNTCNMGNGAYTTYGTNGTNAARGCNGARATHGTNTCNMGNCCNTAYMGNGCN YTNATGGTNGARAARGTNGTNCARYTNTAYTTYTGGATHTAYGARYTNTCNCCNGAYTTY TGGCAYMGNTGYGARGARYTNTCNTGGATGACNTGGGARATHYTNAARGAYTTYGCNTTY MGNATHTGGAGYCAYACNGTNCAYTTYGCNGGNGARGCNGAYCAYTGGATHACNGARCAY GTNYTNACNGGNTCNTTYTCNAARAARGCNATHAARGAYACNGCNATGTGGGGNGTNGAR CAYYTNCARAAYTGYACNTCNTAYYTNGTNTCNTGGAAYGGNTTYTTYCCNGCNTTYGTN CAYTCNYTNMGNTCNTCNTGYYTNCARTTYATHGAYTTYMGNGAYAAYGTNTCNATHMGN GGNTAYYTNTCNGTNGAYGTNGAYGGNGGNMGNCARGARCAYTAYGTNYTNGCNGARMGN ATHTCNMGNGGNAARAARGAYAAYACN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TCNTTYTCNAARCAY YTNAARGARGCNGARGAYMGNYTNAARGARTTYGGNAGYTTYATHTCNAAYATHGGNAAY CAYAGYTAYCAYGAYGARYTNATHGARCARATGAAYCAYYTNGARACNGAYATHGAYAAR AARATHGARACNAARGARAAYGCNTCNTGYAAYAARCARAARGCNGTNCARGAYYTNGAR GCNGARTCNGARGCNYTNTCNTGYAARATHAAYTCNTAYAARAARAGYATHACNYTNYTN CARGARGARYTNAGYCAYYTNACNAARGARAARTCNYTNATGAAYAAYGTNCCNGAYGGN GAYATHATGACNGCN---AARATHAARCARYTNGARGCNGARGAYYTNATGTTYMGNAAR CARYTNGGNATGGARATHMGNAARGTNAARGGNGGNTGYYTNCARATHGCNTTYAAYCAR ATHGAYCCNAARCARCCNAAYTCNYTNTTYYTNTTYTCNYTNAARYTNGAYGARAAYMGN CARTAYATHATHTCNGAYTGYCARCCNGCNATHGCNAAYGTNGAYCAYATHGTNYTNCAR YTNAAYAAYGAYAAYAAYTTYCAYAARTTYATGCAYACNATGMGNCARAARTTY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNAARMGNMGNCAYAGYGAYGTNYTNCAR---GAYCCNTAYAARGGNCCNCARGAR TTYATGGARGCNGGNGTNMGNGGNTTYYTNGTNACNTCNGTNCCNGAYMGNGARGARCAY GCNYTNGAYGARGCNATGAARTGYYTNMGNAARTCNTGYGTNAARYTNTAYGGNGGNATH AARCCNYTNAARAARACNACNTTYGCN------AARGGNTGYGTNATGGTNGAYTTYATG GAYCCNAGYGAYGTNGTNGCNYTNCCNCAYCCNGAYGCN------GAYAARTTYGCNGCN GARGARAARGCNAARGCNGARGCNGCNAARGGNGARGCNAARGARAAYGARGAYATGGAR GARGARAAYAARGCNAAR------GTNGARGAYGTNGCN--------------------- GARGAYCARGARAARAAYGARAAYATGGARGGNGARGARGCNAARGCNGARGARACNAAR GGNGTNGARGGNAAYGARAGYAARGCNAARGARGARAARGARAARGARCARAAYAARAAR GARGARYTNAARAARAARAARMGNGARGARGARGARAARGCN------------------ ------------------------------------------------------------ ------------AARCCNCCNYTNYTNYTNGCNCCNCAYAARTTYAARTGYTTYMGNACN GARYTNMGNAAYATHATGTTYATHAARTCNGAYGTNGTNGAYCCNGTNGARGTNATHCAY GCNGCNTTYGAYYTNATHGTNGAYMGNAARCCNYTNTTYTCNGAYTGYATGAAYCARYTN YTNCCNATHCARGGNGTNTGYGAYAAYGAYTAYAARCARYTNGARATHATGTGYMGNMGN GTNYTNGCNCCNGTNGGNGARCAYYTNGAR---GARCCNCCNAAYTTYGGNGTNATGYTN ATHGAYAARATGTGYGARCCNGGNTCNGARGTNYTNYTNGARGTNGTNMGNAGYTCNATH TGGTGYYTNAAYCCNATGGCNTGGCARAGYTCNCCNTGGTCNGARCCNGAYTTYGTNATH CAYYTNGARGTNATHGGNAGYAARATHATHYTNAGYGTNATGCCNGAYTAYATGAARTAY MGNCARTAYAGYCCNTTYGCNYTNCAYGARATGGGNCAYGGNAARCCNCARGAYGARGAR AARATHYTNMGNGARGCNAARGARGARGARGARMGNGARMGNGARAARGARGARAARAGY MGNGARGGNAARAGYMGNAARAARAARGAYTGGGGNAARAARAARGAYGAYAARGAYAAR AARAARGARGAYAARGARACNAARCARGARGAYGGNGARAARAARGAYGAYGGNGARAAR AARACNGARGARTCNGARGARTCNAGYAARCARCCNGARGCNGCNGARGGN------GAR ACNGTNGARYTNAARGARGARGTNACNGTNACNGARGARCCNACNGAR------GCNGCN CCNGARGARAARAARAGYACNCCNGAYGCNAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TTYGARTCNYTNYTNYTNGARCARGCNCCNACNYTNATHGTNAARTAYYTNATH YTNGAYCARGAYGGNACNTTYCCNGCNYTNYTNTTYAARMGNTCNTTYGGNGTNAAYATH AGYMGNMGN------------ATHAAYTTYGAYGARATGTTYCCNTCNTCNCARAGYTCN GAYACNACNTCNGARTTYGGNYTNAARATGGAYTTYGARTTYGGNGGNGAYGCNTAYAGY MGNATHATGTCNTCNTCNTGYCAYTTYCCNCCNGGNATHATGMGNMGNAGYYTNTCNGTN GAYAGYCARTGYGCNMGNGAYAAYACNGCNGAYATHACNGAYAAYCCNGARGAYAARATH AARACNMGNGTNGGNATHGGNATHAGYYTNATGAARGTN------ATHACNACNYTNGCN YTNTCNAARTAYGGNGAYGGNGARATHCARMGNYTNTGGYTNMGNGGNAGYAARTCNGAY MGNYTNGCNTGYGCNGTNAGYYTNYTNCAYATGTCNYTNGGNTGYGGNCCNYTNCAYMGN MGNCARATHGCNTTYAARCARGAYACNYTNMGNGARGTNYTNCCNATGYTNTTYGTNGAY MGNGCNCCNYTNATHMGNGARAGYATHGTNACNGCNYTNTCNYTNYTNGCNCAYYTNYTN GGNATHATGAARMGNACNCCNAARATHTCNAARGTNGARCCNTGYCCNGAYTCNCARTTY GTNYTNCCNGCNAAYAAYAGYTCNAARCARGAYCAYAARAARGAYAARMGNCAYACNATH GTNTGYGTNTAYGARAGYATHTCNAARGARCAYGAYYTNAAYYTNATHGTNACNGAYGGN GARMGNMGNGTNTTYMGNGCNTGYAARCARATHYTNATGMGNAARTCNGAYGTNTTYTCN GCNATGYTNGGNGGNGGNTAYGCNGARGCNGARAARGTNGAYATHGARTTYTCNGAYATH GGNYTNTCNGGNTTYGARTAYATHATHCAYTAYYTNCAYGGNTGYGARACNGGNTGYTCN GTNATHGAYTCNATHGTNCCNYTNTAYTCNACNYTNGAYAARTGYGARGAYATHYTNACN GTNGCNGAYMGNTTYYTNYTNCAYGARYTNACNAARCAYGTNACNTCNGTNYTNTCNCAY YTNTGYATGTAYCCNCARACNTGYCARGAYATHYTNTAYGTNGCNTCNTAYTAYAARYTN GAYAAYYTNGCNTGYGAYTGYGTNYTNGAR------------------------------ ------------------------------------MGNAARCARTGGTAYAARCCNCAY YTNGGNCARCCNYTNGAYGTNCARTCNMGNAARGCNAARAARGARATHTCNCAYAGYCAY AGYGTNMGNYTNMGNCARYTNAAYCAYGTNYTNTAYGAYAARATHACNGARATHATHAAY ACNGGNGARYTNTCNCARGARATHYTNGAYAARCARGTNTCNATHGTNTCNATGAARATG CAYAARGAYACNAAYAAYYTNAGYATHTAYTGGGAYGCNGAYMGNAARGAYTCNGAYTTY GTNGAYCARYTNYTNCARGCNCAYTCNGGNAARYTNMGNAGYYTNYTNATHTCNTAYCAY ATHYTNGGNMGNATHCCNCAYATHGCNTTYGTNCARGAYAAR---ACNAGYTCNAAYATH AAYCARYTNGARCARYTNTTYGTNGTNGCNGAYTAYGGNCCNGAYTAYGTNCCNGGNTCN AGYGTNGAYGGNAAYACNCAYAARGAYGAYYTNGAYAAYCCNATHGTNACNGARTCNGAY GAYAAYGAYGAYATHYTNTAYAGYYTNACNGARAAYAAYYTNGAYGTNAGYAARCARTCN CARGTNYTNAAYGARCARMGNGAYCARGTNGAYGAYTTYGGNAAYMGN------------ ---------YTNAAYTGYGARAAYTTYTCNGCNAARGARYTNGGNTTYMGNTCNGAYATG TAYGGNYTNAGYMGNGAYGARATGATGAARAARGTNYTNGCNAARAARAARMGNACNGAY GTNTCNGARGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATH TCNGARATGAARACNTTYCARCCNTCNGCNCARYTNTAYAARYTNAAYMGNCAYACNACN ATGTGGGARAAYATHMGNACNCCNGGNAGYCCNCCNYTNAGYCAYCAYGCNTGYGTNGTN AGYGARGAYMGNTAYATGATHYTNATHGGNGGNTGGAAYGGNAARMGNMGNTGYGCNGAY GTNCAYGCNTAYGAYACNCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYTTYCARGCNGCNGARGAYGCNMGNTTY------GTNAAYAAR ACNCARTCNGGNTCN---AARCARCCNATGGARGGNYTNATHYTNAARTTYACNAAYGTN ATGAARGGNTAYCARTAYMGNTGGYTNGTNYTNGAYCCNGARTCNGGNATGYTNGARTAY TTYGARAARGARGARCAYAARAARCARMGNCCNMGNGGNTCNGTNCAYYTNGCNGCNGCN GTNGTNTCNCCNTCNGARGARGAYTCNCARACNTTYATHGTNAAYGCNGCNAAYGGNGAR ATHTAYAARYTNMGNGCNTCNGAYGCNAARGARMGNCARTCNTGGGTNGAYMGNATHMGN TCNACNGCNGARCAYCAYACNGCNAAYATHGCNCAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CAYCARCCNGTNGGNCCNTGYAAYAARACNGTNAARGTNCARACNCCNTTY GGNCARGTNYTNAGYAARACNMGNTAYYTNTGYYTNAARAAYTAYTCNGARGAYTAYTTY ACNYTNGAYTGYYTNAARAARCCNCCNGCNGAYAARACNGARTGGTAYAARATHTGYGGN ACNCCNTAYCCNAAYCAYAARGARTAYATHGTNATHGTNTGYAGYGCNTGYATHYTNGGN YTNACNTGGTTYTAYCARGTNYTNTGYMGNTCNGGNACNCARCCNAARACN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNATHAARTTYGGNGAYAARGTNATHAARGCNGGNGCNAGYTTY GGNMGNCCN------GCNTCNAAYTAYACNAARCCNYTNACNTTYAARGARAARATGMGN CARCAYYTNATHAARGCNATHGARGAYGGNGCNGAYCARAAYGARGTNYTNGCNAAYAAR GGNGGNTCNACNATHTGYACNCARAGYGCNGGN---GTNATGCARCARGTNATGCCNAAR CCNAARGGNCCNCCNATHCCNYTNATGGAYGCNATHGTNTCNTCNACNGCNGGNYTNGCN GCNATGACNGTNACNGCNTCNGARGCNGCNATGCARTCNATGYTNGCNYTNCARAARGAR GCNACNGARAARACNGGNATHGARATHCCNAARTAYTAYAAYCCNGCNGCNATHAAYCCN ATGAARTAYGCNGARCARGTNCARAARMGNAARYTNYTNTGG------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGCNCCNATHCCNGARGAYAAYCAR GARAARCCNCCN---CCNAARGAYGAYTCNGAYYTNAAYTCNTTYTCNACNYTNAAYGTN GGNATGAAYACNGCNGGNTCNGAYTCNAGYGAYGAYAAYGAY---GAYAAYTTYCCNGAY ACNTCNGGNTAYATGYTNYTNCCNCARGARCCNGAYAAYGAYGAYAAYGGNAAYGARAAY TAYATHCAYGAYGAYGAYTCNTAYGARYTNAGYTCNACNATHACNGARACNGAYAGYGAY GGNATHCAYAAYTCNGTNATHAAYGGNACNAAYGGNGCNACNATHCCNAAYGARGTNATH GARTCNGARGGNGGNGCNTCNACNCCNACNGTNGCNGCNTCNGCNTCNTCNTTYCAYCCN GAYTTYYTNGCNAARTTYCCNGAYGGNAARGTNCCNTCNTAYATGCARGTNCCNGAYGTN CCNTCNAGYCAYAARGAYTGYYTNTGGAAYAARAARMGNACNGAYAARAAYATGTCNGCN YTNGAYTCNGCNGARGARAGYAARATHATHAARGCNATGTCNGGNTTY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TTYAGYYTNAAYYTNTGYGTNGGNCCNACNTAYGAYCAR GARTGYGCNYTNCAYTTYAAYCCNMGNYTNGAYGAYAAYAARGTNGTNMGNAAYAGYYTN ATHAAYGGNTCNTGGGGNAAYGARGARACNTCNGGNGGNTGYCCNTTYMGNMGNGGNCAY GGNTTYGARYTNCAYATGAARGTNCAYCAYCAYGGNTAYCARGTNACNGTNAAYCAYMGN CAYTTYTGYGARTTYAAYCAYMGNATHCCNAARGARAGYGTNCARTTYATHTAYATHGAR GGNGAYGTNGCNATHAAYTAYATHCARTTYMGNGGNGGNCAYTCNCAYCAYGCNCCN--- ---CCNGCNGCNGCNGGNTAY------------CCNGCNTAYCCNCCNCCNCCNTCNTTY CCNGGNGGNCCNTCNTAYCCNCCNGCNCCNCCNTAYCCNCCNACNCCNGGNTAYCCNGGN GCNGGNAGYGGNCCNGCNTAYAAYCCNCCNGTNCCNTTYACNTCNCCNATHCCNGGNGGN YTNTAYCCNGGNAARATHATHTAYATHACNGGNGTNCCNAAYCCNAAYCCNAGYMGNTTY ACNGTNAAYYTNCARTGYGGNCCNTAYGAYTCNGGNGAYTTYGCNATGCAYTTYGAYGTN MGNTTYAAYTAYGGNAGYGAYMGNAAYCARGTNGTNMGNACNCAYAARCARGGNGGNAAY TAYGGNGGNGARGARAARGGNATHAGYCAYTTYCCNTTYTAYCCNAAYACNAAYTTYGAR ATGATGATHYTNACNGARCCNTCNAGYTTYAARATHGCNGTNAAYAAYCARCAYTTYGTN GARTTYAAYCAYMGNYTN---CCNTTYAAYTGYGCNGAYCAYGTNAAYATHGTNGGNGAY GTNMGNYTNTCNCARGTNMGNTTYCARACNAGYACNTTYGTNCCNAAYTTYYTNATHAGY TCNGGNACNGGNYTNACNCCNACNYTNACNCCNACNACNYTNGCNACNATHGARCARTCN TTYATGGARATGCARCAYTCNGGNGCNMGNGAYCCNGTNACNCARAGYGGNTTYGTNCCN CCNGTNGTNGARCCN------GCNAAYAGYGCNGAYCAYTCNCARGAYAGYTTYGARAAY TCNTCNTCNGAYCCNGARTGGGARCCNAARCCNAARAAR---TTYYTNAARGARGGNGTN AAYGGNGTNGAYTAYATHGTNACNTCNACNGGNACNGTNAAYGTNGCNCCNCARMGNAAR TAYACNMGNMGNAAYAARGAYGARAAR--------------------------------- ---------------AARMGNAARGTNGGNGARAAYCAYYTNAAYTCNTGGYTNCARAAR ATHGGNMGNGGNAARAARAARACNAAYATHGTNGARGGNGARAARGAYCAYTCNGAYATH AARATHAGYCAYTAYYTNTGYCARYTNCARAAYTTYATGGGNATHATHMGNAGYATGTCN TCNCARGTNGAYACNATGGARGGNATGATHTAYGAYGCNGAYAARTCNACNTGGYTNAAR GARTAYGAYTCNGTNGARYTNYTNAARTCNAARCAYAARAGYYTNCARAAYGTNATHAAR AARTCNACNGTNGARMGNGTNAARAARAARYTNGAYGGNATHMGNAARAARMGNACNMGN YTNAARAARTCNMGNCAYYTNMGNCAYYTNGARAARCARGARGTNGARGAYGCNMGNCAR GTNAARGARAARGARATHAGYGAYTGGCARCARAARMGNYTNACNYTNATGAARGARGAY YTNYTNMGNACNAARMGNAARGARGARATGGAYCARACNYTNGGNGAYGTNACNAARAAR ATHAAYGAYGCNAAYMGNYTNATHGARACNATGATGGCNYTNGARAARYTNMGNYTNATH MGNCARGAYGCNGCNAARAARMGNGGNGAYAAYGAYATHGGNGARTCNMGNCARAGYTTY GARCARAARATHGCNGAYATGACNMGNYTNGTNMGNTCNCARYTNGARGTNTAYAARGAR GARGARCARCARYTNMGNAARATGATHAARTCNGARCAYGARGARTCNAGYAARAARGAR AARCARYTNCARGARAARAARGAYCARGARGARCARGARCARAARGAYGARGARYTNMGN AARYTNYTNTTYGGN------GAYGAYATHGAYGAYYTNYTNGAYGARGTNGARACNAAR TAYGTN---------------AAYMGNAAYAARAARCCNGARTCNAARYTNAARTGYACN GTNCCNCCNAARCCNACNGCNGTNGAYGAYGCNATHAAYGAYATHYTNGAYYTNGAYYTN GARGAYGAYGTNTCNAARACNCARGTNTCNAGYAAYAGYAAYCCNTCNGGNTCNTCNGTN AAYGGN---------MGNAARGARGCNACNAARAARTGYTTYCCNGTNTTYYTNGGNGGN AGYAARGAYGARGTNGGNYTNGGNACNACNGTNAARACNMGNGCNTGYGAYCARYTNMGN TGYACNGCNTGYGAYTTYMGNGTNTGYTAYTTYGARGAYTTYTCNTGGAARAARGAYACN AAYTAYYTNTTYYTNMGNAAYAAYGTNCCNGAYTTYCARAARYTNAARTCNAAYYTNTGY MGNCARAARGGNTGYMGNGCNTAYTGYTGYCARTGYAGYTGGMGNGAYATHCAYYTNYTN AARGARYTNTCNGAYCCNGCNYTNAARTGGGTNTGYGGNAARCAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TAYYTNTAYTGYCCNTAYGAYGAYACNCAY GARATHYTNGCNAARAGYTTYAGYGCNCAYYTNATHAARTGYMGNAARAAYTAYCCNGGN CARAARYTNGTNTCNTGYCCNYTNGAYAGYACNCAYAARATHCCNAARCCNGARATHCCN TAYCAYGTNTCNGTNTGYGAYAARMGNTAYYTNATGGAYMGNGAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------AAYYTNGTNTTYATGTTYGGNCCNCCNATHYTNGAYAARYTNAGY TAYYTNCCNGARTCNTGGTTYMGNGAYGAYCAYATHGARATHGTNCCNYTNTTYGARGAY AAYCCNGCNTTYGGNYTNMGNGAYYTNTCNYTNCARATHATHTCNGARYTNAARAARGGN ACNCARGTNTTYGTNGAYGAYGARYTNCAYTGYCARAAYGCNMGNAARAGYATHYTNAGY ACNGTNAARAARAARGTNCCNGAYTGYMGNGTNYTNYTNGTNAARGTNGTNCCNGCNCAY GGNYTNTTYCARGTNYTNTGGACN---------CAYCARAAYGCNAAYGGNYTNCAYAAR TAYTCNTGYCARATHAARAAYGCNAAYATHCARMGNTGGTTYGAYTCNTCNTCNATHYTN ATHGAYTAYCARTCNGGNTAYGTNGAYGARCCNGAYCARACNGARGGNTTYAARATHAAR GARATHAAYGCNTCNTTYCARATHCARTCNAAYTTYAARTTYGARATHCCNGCNYTNTTY ATHCARTGGGARGCNGCNATGTCNGAYTCNAGYGAYGTNGAYAARATHYTNTGYGARGTN TGYGAYAARTGGACNGCNYTNAAYAGYCAYGGNMGNATHATHYTNATHTAYAGYGGNAGY AARGAYYTNAARYTNGAR------------GAYAARGARMGNTGYGTNYTNCARAAYYTN AARMGNTTYGCNATHMGNATHCAYCARYTNGTNTAYYTNGTNAARYTNATHAARTCNAAY GTNAAYAGYTTYTGYGTNCCNCCNCARCCNGGNATHYTNGCNTTYYTNCARGCNCARCAY YTNATHAAYYTNCARGCNAARCAYACNATGTAYATHTTYGARAGYACNGAYCAYATGAAR ATGGCNCARGCNGCNGGNATHAARCAYATHAARGTNACNAARGCNYTNAARAAYCCNCAR CARATHYTNAGYAGYYTNTGYATHAAYCCNCCNGTNCCNGCNATGYTNAARGAYGTNMGN TTYGTNAARAGY---GGNGAY------GGNAARGCNTCNATHCCNYTNYTNGAYGARTAY GARGAYAAYCAYCAYMGNTTY---ATHTCNCAYTCNTAYCARGAYGGNYTNGARGARTTY GTNTTYYTNCCNTCNGCNGGNGARTTYTCNAARGTNCARGARAAYTTYGCNAGYTTYGCN AAYCCNACNGGN------------------AGYAARGCNATHTCNCARGARYTNGAYATH YTNACNGGNACNAGYAARACNAGYCAYAARAARYTNGARTCNACNAARGCNACNTCNYTN CARACNCAYCCNAAYYTNCCNGTNTGGATGAARMGNCARYTNAARMGNAARTCNACNGAR TCNTCNYTNTCNGAYYTNGAYAGYAAYGAYCARGARTCNTCNTTYMGNTTYATHAARACN GTNTAYATHATGAGYGARAARGARYTNAARGARATGGCNGTNCARGTNATHAAYCARGCN GGNAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGGAR AAYAAYAAYGCNATHGCNGCNAAR---TCNYTNGAYGGNGARACNAARATHGARAAYGTN AARCCNACNGCNGAR------GAYAAYTCNMGNAAYMGNGGNTAYMGNTAYAAYMGNMGN MGNCARCARTTYMGNMGNGARGTNAAYCCNGARGAYGARACNGGNAARGCNGCNATHMGN MGNAARATHTGGGAYAAYYTNGARGAYAAYAAYYTNGTNTCNGCNCCNMGNCCNTGYCAY TAYMGNATHCCNAAYTTYGARGGNGCNTCNGARGCNGCNGAYMGNYTNAARTCNYTNGAY GARTTYAAYAARGCNMGNACNATHAARGTNAAYCCNGAYAARGCNCARGARCAYGCNMGN TTYYTNGTNYTNGARGARGARAARGARYTNGTNYTNYTNAAYCARAAYCARAARGAYYTN ATGGTNCCNACNCCNGARYTNAARTCNAGYYTNYTNAAYMGNGTNGTNCCNCCNGARGGN GCNAAYAARGARGARYTNMGNCAYTGYTGYACNACNCARGGNGTNAARGARAAYAGYAAR GARATHGGNYTNGAYGAYAARACNAAYYTNGAYYTNATHATHGTNGGNAGYGTNGCNGTN TCNMGNAAYGGNTAYMGNATHGGNAARGGNAARGGNTAYGCNGAYYTNGARTAYGCNATG ATGMGNACNYTNGGNGCNGCNAAYGCNAARACNGTNGTNGTNACNTCNGTNCAYGAYTCN CARGTNGTNGARATHCCNGAYGAYYTNGTNGAYGARCAYGAYATHACNGTNGAYTAYATH YTNACNCCNACNGARYTNATHAARACNAAYGCNAGYMGNCCNMGNCCNTCNGGNGTNATH TGGAAYCAYYTNGCNGTNAAYAARTTYTAYCARATHCCNGTNYTNMGNCARYTNMGNAAR AAYGARMGNGAYAAYGGNAARGAYGTNYTNYTNAARGAYCARAARGARGARGAYGARGAY CCNGTNGAYTCNATGGARCCNCCNMGNCCNMGNMGNTAYGTNMGNTAYTAYCARAAYGCN GGNGGNTAYMGNGGNMGNGGNMGNCCNTAYGGNMGN---TTYMGNMGNGGNGGNGGNMGN MGNMGNCARTAYGAYGAYGGNGARGAYAGYAAYAARGARAAYTTYGAYGGNGGNGARGAY TCNGGNGCNGAYGGNGAYAAYGARGGNMGNGTNMGNAAYMGNMGNCCNCCNCCNMGNAAY AAYTAYMGNAAYMGNMGNTTYMGNMGNGGNGGNGGNGGNAARGTN---MGNGCNTCNGAR TCNGARCAYAGYGAYGGNGGNGGNGARAGYAAYMGNGAYGAYGGNGAYGAYMGNMGNCCN MGNMGNTAYAAYCCN---AAYMGNMGNMGNTTYAAYCCNAAY---AAYMGNMGNMGNMGN TAYAAYGGNAAYMGN------MGNGAYAAYMGNAAYTCNGCNGAYCAYTCNGGNAGYGAY GGNGARCARAARAAYTCNGGNGAYGARGAYGGNGARGGNMGNMGNCCNCARMGNCARMGN TAYMGNACNAAYCCNGAYGCNGTNGTNTTYATHGGNGCNYTNGCNMGNGAYYTNMGNGTN AGYGCNYTNAARACNGARYTNMGNAGYCAYAAYGTNAAYCCNATHMGNYTNYTNTGGMGN GGNGGNMGNGGNTAYGCNTTYYTNTTYTTYATGGARACNGAYAAYGCNAARGARGCNGTN GAYGTNYTNACNGGNMGNGARYTNAAYGGNMGNGARATGAARGTNGARATGGCNAAYATG GAYMGNGAYTCNMGNMGNMGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGCCNGTNAGYAARGTNGTNGAYAARTCNGGNMGNGGNATH AAYYTNGTNCCNTTYCAR---------GARATHTTYATHTCNCCNCARTTYAGYGARCAY GCNGTNAAYAGYATGGGNGAYTTYCCNYTNMGNGARGAYGAYGTNATHYTNGTNAGYTAY CCNAARTCNGGNTGYCAYTGGGGNTGGGARATHYTNMGNATHYTNGTNTCNGGNAARATH ACNGAYGAYTCNYTNAGYAARGARGAYTAYATGATGGARTGGMGN---CCNGCNCARGAR ATGGCNTCNYTNCCNAGYCCNMGNGTNYTNAAYAAYCAYATGCCNTTYCAYTCNCARCCN MGNGAYYTNYTNACNAARAARCCNAARGTNGTNYTNYTNTAYMGNAAYTTYAARGAYGTN GCNGTNTCNTTYTTYCAYCAYCAYGTNGCNATHACNGAYTAYGARTAYCCNGGNGAYGAY TTYGGNTCNTAYYTNCARMGNYTNATH--------------------------------- ------------------------------------------------------------ ------------------GAYGGNCARGTNGARTCNGGNAAYCCNTTYAAYTTYACNAAY GGNTGGGARAARGGNATGMGNGAYAAYCCNGAYYTNCCNGTNTAYTGYYTNGCNTAYGAR GARATGMGNCARAAYCCNATGTCNGARATGMGNMGNYTNTGYGARTTYYTNGGNAARGAR CAYCAYGAYAAYTTYYTNCARCARGCNTGYGAYGTNACNAGYTTYGAYTAYATGAARAAR ACNAARGGNGTNGTNAAR---------------CCNGTNTTYTAYMGNAARGGNCARGTN GGNGAYTGGAARAAYCAYTTYACNGTNACNYTNAAYGARTGGTTYGAYGAYATHATHMGN TCNGARATGTCNGAYACNMGNYTNAARTTYCARTAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CCNACNATHYTNTTYATGCCNCAYTGYGGNAARGCNYTNTAYAAYAAYYTN GTNTGGGCNAAYYTNACNACNYTNGAYAAYYTNGTNATHATHGGNAAYAGYTTYTCNGCN ATGYTNGARMGNATGCCNCAYMGNYTNYTNAGYAARACNGCNAAYTAYGTNATHAARGTN GCNCCNTTYATGYTNGARACNCCNYTNAARACNTCNTCNTTYGTNCAYTCNGAYGTNTTY AAYGAYYTNGCNGTNCAYACNTTYCCNMGNTCNAARYTNGAYACNGCNCCNACNGAYTTY TGGGARYTNAAYGAYGARCCNAARTAYAGYCARGARGAYGTNGARATHATH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNGGNACNAARGTNTCNAGYYTNGGN ACNGCNGARYTNGARMGNATGMGNGARGARMGNMGNCARYTNTCNCARGARYTNMGNGAR GARCARAAYCARYTNGAYMGNGTNAARCARGAYAARAARACNYTNGARGGNGAYGTNACN MGNYTNAARATGGCNMGNGARCARCARAAYAARAARYTNAGYGARATGMGNGARMGNGTN GARGGNAARYTNAARGARTTYGARGGNYTNCARGAYMGNTTYACNCAYGARGTNGARGGN CARMGN------------------GCNMGNGCNGTNMGNTCNGAYYTNTCNACNGCNCCN CCNTCNCCNGTNAARYTNACNATGAAYGAYYTNCARTCNYTNCCNTCNGAYTCNAAYGCN MGNYTNAGYGAYGARGAY---GAYGAYGARGAYCCNYTNMGNGGNYTNCAYMGNAGYAAR TCNTTYAARCCNTCNAGYYTNTGGTAYGAYAGYYTNTCNATGGARCCNGAYGCNATGGGN ATHCAYYTNGCNGGNACNGAYMGNAGYGGNATHAARGARTAYYTNCAYAARGARGGNYTN ATHATHACNMGNGCNAARGCNTTYYTNCARAARCARMGNMGNACNYTNAARCARMGNCAR TCNGCNYTNGCNGCNGCNAARCARGARYTNGTNAARGAYAGYAGYATHYTNCARCARGGN AAYCCNACNGARGARGCNACNGARATGYTNGARAARGTNMGNGAYACNYTNGARACNGAR MGNGCNCARATHGAYGCNATHGARTCNMGNTTYAAYTCNGAYTCNAARYTNYTNCARGAR AARGARGARAARTAYCARMGNYTNCARGGNYTNGCNAARGARAAYGARAGYGARGAYGAR TCNGARTAYAGYCCNTTYGCNCAYCCNTTYCAYAARGTNAARATHCCNACNATGGAYYTN AGYGARGAYGARAGYAGYGGNGTNAGYAGYTCNAAYGCNAGYYTNGAYGARTAYTTYCAR GGNMGNCAYAARCARTTYACNAGYACNACNMGNGCNAGYGARATGCCNGGNAGYGCNGGN GAYGAYYTNTCNACNGTNYTNCAYMGNATHAAYCAYGARYTNTCNCAYGTNYTNAGYGTN ATHGGNAARGAYGGNAAYTCNTCNYTNGCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ACNACNGTNCAYACNATGGAYGTNGCNTAYGAYATHCARAGYGGNTTY YTNMGNMGNCCNAAYCAYTTYAAYACNTCNTGGGAYTCNGCNMGNTTYGARGTNTAYGGN CAYAARTGGGCNGAYATHTCNGARCAYGGNTTYGGNGTNAGYATHYTNAAYGAYTGYAAR TAYGGNTAYTCNGCNGTNGAYGGNATHATHMGNYTNTCNYTNYTNMGNTCNCCNAARAGY CCNGAYCCNACNGCNGAYATGGGNGTNCAYACNTTYTCNTAYGCNATGATGCCNCAYGTN GGNAGYTTYCARGAYGCNGGNGTNATHCARCARGCNYTNGCNTTYAAYTGYCCNYTNMGN ACN---------------GGNGTNGGNYTNGAYCARGGNATHYTNCCNTCNTCNYTNTTY MGNACNAGYAGYCCNCARGTNGCNGTNCARACNGTNAARATGGCNGARGAYAARAGYTCN ACNATHATHYTNMGNYTNAAYGARGTNTTYGGNGGNAGYGTNGARGTNTCNATHTTYTCN AGYGCNGTNATHTCNGAYATHGARGTNTGYAAYGGNYTNGAR------GAYGTNATHGAR GAYTAYGAYYTNCARYTNAARACNGTNGARATHGARACNGGNTCNCARATHTGYYTNTTY ATGAARCCNTTYCARATHGTNAGYYTNMGNTGYACNYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARGARAAYCCNAAYYTN---ACNTGYATGATHTGYYTNGAR GARTAYMGNGARGGNGAYAARATHMGNACNYTNCCNTGYATHCAYTGYTTYCAYGARAAR TGYATHGAYGAYTGGYTNNNNMGNGCNACNACNTGYCCNYTNTGYAARYTNGAYYTNATG ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GCNMGNGTNAARGCNCAYAAYCAYGCNGGNGARAGYGARTAYAGY GAYGTNGTNAAYYTNCARACNGCNGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARACN TTYAARCARTAYGTNGTNAAYYTNATHTAYGARTGGGTNACNGGNYTNCAYCCNGTNCCN GGNGTNTGGAARGTNTGGAAYGARGARGGNYTNGARGGNAGYCARACNAAYMGNGARAAY GARACNGCNAARAARATGYTNGARGCNGCNGCNYTNAAYAARAARGTNGARYTNAGYYTN GAYATGGARTCNTTYGCNAARGTNATHGAYAARYTNGGNATHGARCCNGAYACNACNCCN CARGGNAAYYTNTCNMGNGARATHACNAARACNACNAAYMGNATHTCNYTN------CAY TCNMGNGGNAARCCNYTNATHTCNAARCARGARTCNCAYCARATHGGNCCNGGNCCNGAY TAYGARMGNGTNAARTTYAAYACNTCNGGNMGNAGYCCNYTNATHGCNCAYTAYYTNCAY ATGMGNCARYTNMGNAAYTAYAARCARCCNGGNATHAARGTNMGNMGNACNGARATHYTN AARYTNCCNCCNGAYGGNCCNACNTAYCARCARTTYATHGCNAAYACNYTNAGYAARGCN GARTCNYTNGARMGNGARTAYACNMGNATHTGYGARCARACNTCNACNGCNATHYTNGAR YTNGARMGNCAYAARMGNGAYTCNAAYMGNGARATHGCNGARYTNAARAAYGCNYTNACN AAYATHAARAGYATHCCNGARMGNMGNTCNYTNATGGARAARATHTCNGARTAYAARGAY YTNGTNATHAARGARAARCCNYTNYTNGARCARAARAGYTCNTCNTAYTCNACNGAYGAR GARGAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNAARYTNGCNGAYATGGARMGNACNMGNMGNGARATHMGNCARMGN TGGTCNACNYTNAARTTYATGGAYACNCARCAYAAYTCNMGNCAY------------CAY YTNATHAAYGAYTGYCCNGARTCNCCNACNACNATHAAYGTNCCNGGNATGACNACNTCN AARATHAAYGGNAAYAAYCARGARCCNAAYAAYAARGGNTGGACNGARGARCCNYTNYTN TTYACNAARCCNAARAGYAARCCNGTNATHTAYTAYCCNTAYAGYGCN------------ ---AAYGAYYTN---CARACNGTNAAYGTNCCNGGNMGNCARCAYGTNACNYTNAAYCAR GGNACNYTNGAYMGNATHYTNGARGAYMGNGGNMGNTTYGARGARCAYYTNMGNAARMGN TCNCAYCAYCCNGCNGGNAARTTYGAYCCNTGGMGNYTNGTNGARGARATHTCNGAYGAR ATHYTNGCNGARTGYYTNCARGARGTNTCNGARGARGTNGARAARGTNAGYGARGARATH GCNAAYCARATGTAYAARTCNGARTTYATGATHACNGGNMGNCCNTCNGARACN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATHYTNAAYACNYTN GAYGTNGAYGGNTAYTCNTCNYTNCAYYTNTCNGTNATHAAYGGNGAYGTNAGYGCNACN AARYTNYTNYTNAARYTNGGNTCNGAYTGYGAYAARNNNTCNCAYAGYGGNAAYACNGCN YTNTCNYTNTCNATHGCNTAYCARCAYCAYCAYYTNYTNCCNYTNTTYYTNCAYCAYTCN AAYGTNAAYACNCARGAYTTYGAYCAYGAYACNCCNYTNATGTTYGCNGCNTGGAAYAAR CARCCNCARATHYTNTCNACNYTNATHCARTGYGGNGCNGAYYTNAAYTCNGTNAAYAAR TAYGGNACNACNGCNYTNTGGAAYGCNGTNTAYTCNTCNTCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGGCN TCNTCNACNATHYTNYTNYTNGTNYTNGTNGGNGCNYTNGGNYTNGTNACNTCNCARMGN GAYTTYGAYMGNGAYMGNYTNGAYMGNGARMGNGARMGNGARTTYGTNMGN------CCN GCNGARGGNTGYATHGGNAARGTNATGGAYATHTTYTTYATHYTNGAYTCNTCNTCNTCN ATHTAYATHAAYGAYTAYATGTCNCARCAYGGNTTYATHMGNGAYGTNATHAGYMGNTTY GAYGTNAGYCCNNNNAGYACNMGNGTNGGNNNNNNNACNTAYAGYGAYGAYNNNGARMGN CCNNNNATHTCNYTNAAYNNNNNNACNGAYAARAAYNNNYTNYTNAAYAGYATHTCNNNN NNNAAYYTNCCNTAYMGNACNGGNNNNACNAAYACNGAYNNNGCNATHMGNTAYNNNMGN CANYTNNNNGARYTNMGNCARGANNNNNNNAARGTNNNNGTNNNNNNNACNNNNGGNGGN TCNMGNNNNCCNNNNTCNNNNNNNMGNGARGCNGARYTNGCNMGNNNNNNNGGNTTYTAY NNNTTYGTNGTNGGNNNNGGNNNNTAYNNNGANGARMGNGARTGGMGNGCNNNNGCNNNN GAYCCNGAYTCNAGYTTYGTNTAYAAYATHACNNNNCCNMGNTTYATGGARNNNNNNAAR YTNNNNYTNCCNCCNCARGCNTGYTCNYTNCCNNNNNNNNNNNNNNNNNNNNNNTGYAAY GTNAAYCARYTNTCNGARGTNTAYTTYGTNGCNNNNMGNAGYGCNAGYNNNAARGCNATH GANYTNATHNNNNNNTTYAARMGNMGNACNNNNGAYCARNNNNNNNNNYTNMGNYTNNNN TAYATGATHGARGCNTGYNNNNNNNNNACNGAYNNNNNNNNNGAYGAYNNNGAYNNNNNN ---TGYGAYMGNNNNGGNCCNAGYMGNGGNGAYACNNNNGARTCNGTNNNNGCNYTNTTY ACNMGNNNNMGNTCNGTNGCNMGNMGNNNNNNNNNNNNNNNNNNNNNNNNNCARGTNNNN GTNYTNTTYGTNGAYGAYNNNACNATGAGYYTNNNNMGNNNNTCNTGGNNNNNNAAYGCN MGNNNNGCNNNNNNNNNNGANGAYGTNACNNNNATHGTNGTNGAYYTNGGNACNMGNACN TAYNNNNNNTTYNNNNNNMGNATNNNNNNNAAYMGNAAYAAYATHATHMGNTTYYTNNNN GGNNNNYTNGAYAAYCARNNNNNNTCNCARMGNYTNTTYNNNNNNNNNACNTGYTCNGCN ATGGCNGAYACNAGY------CCNGAYYTNYTNTTYGAYAGYCARCCNGARAGYTCNGGN TAYTCNAAYGAYGAYTTYGARAARGTNGAYGCNCCNGGNGGNGGNTTYAGYCAYGAYGAY GTNACNGCNGCNGCNTCNGGNGCNTAY------GAYYTNGAYCARGAYGCNGARATHTCN ACNACNACNGAYGTN------GCNGGNGARGARGARGCNGARGCNGAYMGNTTY---GCN ATGGGNTCNCARGAYATGAAYGCNTAYCCNTCN------GARCCNYTNATHTCNTGGGGN GAYGAR------------------------------------------GARGTNACNTCN CARGTNCARCCNTCNGCNCCNGTNCCNGARAGYGARCCNYTNGTNAAYTTYGTNGAY--- ---GAYAGYYTN---TCNGTNGAYGAY------TTYATGCCNATHAARGARCCNGTNCCN CCNTAYAGYACNACNCCNGARCCN---AGYTTYTCNTCNGTNAGYAAYACNYTNCCNACN CAYGAYYTNGAYGARTTYYTNGARCCNAARMGNGARGARAGYGARACNGARAGYAARCCN GTNTCNGAYCARACN------ACNGTNGARGCNGCNGARGGNTCNTGGYTNAARGGNGTN GAYCCNMGN---------------------------------GTNATHGAYYTNATHTAY TGGMGNGAYGTNAARACNACNGGNGTNGTNTTYGGNGCNATGYTNGTNGTNYTNYTNTCN YTNGCNATHTTYTCNYTNYTNAGYGTNYTNGCNTAYYTNTCNYTNGCNGTNYTNACNGTN ACNTTYAGYTTYACNGTNTAYAARAARATHATGGGNGCNGTNCARAARTCNAAYGAYGGN CAYCCNTTYAGYCARYTNATHAAYATGGAYYTNACNYTNAGYGARGAYAARYTNAARAGY GTNATHCARAGYTTYYTNAARAAYGTNAAYTGYACNGTNAGYGARYTNMGNMGNYTNTTY YTNATHGARGAYATGGTNGAYTCNATHAARTTYGGNYTNYTNYTNTGGGTNYTNACNTAY GTNGGNGCNTGGTTYAAYGGNATGACNYTNGTNATHYTNATHGTNATHCAYGTNTTYACN YTNCCNAARATHTAYGARACNTAYAARGTNCARATHGAYAAYTAYYTNGCNYTNGCNAAR GCNCARGTNGAYAAYGTNYTNAAYATHATHCARAGYAARYTNCCNTTYYTNAARAARAAR GARAARGCNCAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARTAYGARMGNGARGGNTGGACNTTYCAYAGYAARGGNYTNTGGTAYTAY YTNAARAAYGARCAYYTNCCNMGNYTNACNYTNATHGGNTCNCCNAAYTTYGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AGYATHGCNAARATHATHTCNCCNMGNAGYTTY GTNACNGTNGGNGGNTCNGAYMGNGAYTCNGCNMGNGTNGTNMGNTAYGCNGTNAGYATH GAYTAYCCNAARCCNYTNAARGARGARGGNATGGCNMGNGGNATHAAYGGNCCNTAYGGN GCNMGNYTNACNCARGAYCCNCARAAYTCNGARAARACNMGNGCNGARYTNATHATGCAR ATHGAYTTYCARGGNAARATHCCNMGNAARTTYGTNGARAGYAAYATHCCNGGNTCNATH GTNAAYTCNTAYGARGCNTAYAARACNTAYATGAAYAARAAYGGNYTNTTYATGTGGMGN TCNMGNCAYYTNMGNAARGGNMGNCARATHYTNAAYYTNGTNCARMGNCARYTNGCNACN GARGCNGGNGGNGCNAGYAAYGTNCCNCCN---CCNYTNCCNCCNCCNAARTCNMGNGGN TTYGGNYTNGTNAARTTYYTNGGNYTNGGNATHCCNYTNGCNACNGGNGGNATHGTNGGN TAYGCNTGGTAYGAYAARGAYTTYMGNAARCARYTNGARGARAAYGTNCCNTAYTCNAAR GARYTNYTNGARAAYGTNYTNCCNCCNYTNGARCCN---GCNACNCCNAGYAGYCCNTCN AARAARMGNGARAARCCNCCNYTNTTYGAYTCNAARTCNYTNCCNGTNCAR--------- ------CARTCNTCNTCNGTNGARGTNMGNGGNAARCCNGAYGGNYTNGCNGTNTCNAAR CARGAYGTNGARAARGAYAARAARATHAGYYTNGARCARCAR------------YTNAAR AAY---AARCARGAYGARGARAARGCNGAYAAYGCNGCNYTNGARGTNGTNATHGAYAAR YTNYTNGARTCNGCNCAYAAYTGGGTNTCNGARGCNGCNMGNGCNCARGTNGAYGTNGCN AARGCNACNAARAAYCAYACNGCNYTNYTNAARAARGCNATGGAYGAYTCNACNGAYATH YTNCAYAARGAYTCNGARTGGGARGCNGTNACNATHGCNTTYAARGARMGNGARATHGCN GTNAAYMGNGCNAAYGARYTNGTNGAYGARGCNMGNAARAGYATHGARAARATGAARMGN GTNYTNGAYGARGCNAARGCNAAYAARGTNACNATGAARAAYTCNGCNATHTTYCCNGCN ACNAARAARYTNTCNGAYTTYACNAARGARATGTCNACNGCNGCNGCNCARGTNMGNCAR GCNGARTCNGAYGCNAARGTNATGYTNAARTAYAARGAYYTNATHGAYAARGGNAARMGN CARTTYCARYTNGARYTNGARAGYYTNATGCCNGAYGTNAARTCNGGN---AARGGNMGN AARYTNACNGARGARGARYTNAAYGCNYTNATHGCNCAYGCNCAYMGNMGNATHGARCAR YTNCARAARCARATHGCNGARCAYYTNGCNATGGARCARAARMGNYTNACNCARTCNYTN GARGCNCARAARGARCARGAYMGNYTNATHACNGARTCNGCNGTNAARGAYGARTGYAGY MGNYTNAGYCARGARTTYGAYYTNGARAARCARAARATGGARYTNGAYTTYTAYGCNMGN ATGGARACNGAYGTNMGNAARCARYTNAGYMGNCARGCNGCNGCNCAYAGYGAYCAYYTN AARGAYGTNYTNGCNGTNCARGARAARGARYTNAAYGCNGAYTTYGARMGNAARATGAAY GTNAARYTNYTNGARGARMGNGARAARTTYCARACNGARACNTCNAGYTGGATHTCNMGN YTNAARGGNATHGARGCNGCNGTNGAYGCNMGNGCNGCNAGYGARAARYTNGCNMGNACN GCNCARGAYYTNTGGYTNGCNTGYATHGCNYTNAAYTCNACNATHYTNTTYGGNAAYGAR GAYGARGGNCARTCNYTNACNCCNYTNCARCAYCARGTNGARGCNGTNATHAAYTCNTCN AAYAARCAYCCNTTYGTNGARACNGTNGCNAAYACNATHTCNCCNATHGCNYTNGARMGN GGNATHTAYACNGARAAYGAYYTNMGNGAYMGNTTYGTNCAYGTNGCNCARGTNAGYMGN MGNYTNGGNYTNATHCARGARTCNAAYGCNTCNYTNTAYAARTAYYTNGTNTCNTTYYTN CAYTCNTTYTTYACNGTNAAYAAYGTNGCNGCNTAYTCNGARAARGAYYTNGTNTCNYTN GAYGAYATGGAYAAYTTYGARYTNGTNGCNAAYGCNCARTAYTGGATGGARAARGGNAAY YTNGARATHGCNGTNMGNTTYATGTGYCARYTNACNGGNGARTCNCARAAYGCNGCNAAR GAYTGGATHACNGARGCNATGYTNYTNYTNGARACNMGNCARGCNGCNAAYACNATHATH GCNTTYGCNTCNGCNACNGGNYTNGCNGCNACNTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYGARAARMGNGCNATHGAR YTNAARATHCCNTTYACNATHGARCARATHGTNGAYTCNCCNGTNGARACNTTYAAYGAY ATHYTNACNAARTAYAAYYTNAAYGARGARCARYTNTCNYTNGTNMGNGAYATHMGNMGN MGNGGNAARAAYAARYTNGCNGCNCARAAYTGYMGNAARMGNAARGTNGGNGCNATHGTN ACNYTNTCNGAYGARATGGTNGARYTNCARAARGTNMGNGAYMGNYTNAARGCNGARMGN GCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGYTNAAYAARGTNACNCCNYTN YTNMGNTTYGCNCCNMGNGTNMGNAAYATHMGNTGYATGAGYGGNGGNCAYGAYGTNCCN GCNCAYTTYAARCCNATHMGNCARATHTGYGARGARAAYAARAGYCAYATGAAYTTYATG CCNGTNCCNGARGGNTCNTGGCARGARGCNTAYAAYGCNACNAAYGCNAARAAYAAYAAR YTNYTNATHGCNAGYGTNGTNGCNGTNATHGGNACNTTYGCNATGYTNTAYTCNTCNGGN TGYATHTAYYTNCAYGGNGCNCCNCCN---------YTNAARGAYAARGGNACNMGNATH AARGTNCCNCCNAARYTNGGNAARYTNATHGCNGARAAYTAYGCNYTNTCNGARAARTGY TCNACNGGNAARYTNGTNAARAARGTNCCNGAYTCNGAYATHGCNCARAAYTTYATHGAY MGNYTN---AAYGCNCARAAYGAYGTNAGYCARGARYTNTGGGCNMGNGCNAARGCNYTN TCNTGYYTNCARAGYCAYCARYTNATGYTNAARTCNYTNCAYTCNYTNGGNATGGARAAY YTNACNGARAAYTCNCCNATHGAYATHGTNTAYMGNACNAARMGNYTNYTNGARTTYATH YTNACNACNTTYGCNCARACNCARGARGARGCNGAYTAYTTYTCNAARGTNCARTTYMGN CAYTCNCCNCAYGGNGARAAYTTYGTNAARTCN---------------------YTNTTY TCNAGYCARGAYAAYGARTCNCARAARYTNCARMGNGAYMGN---------TTYGTNAAR GCNGCNYTNGARTGYACNTAYYTNTGGACNMGNYTNCARTTYGARMGNGAYYTNCAYGCN YTNCARYTNCAYYTNGTNTCNYTNACNGARGCNGARTGGTGGGAYGCNYTNTCNAGYCAY CCNGARAAYCAYAGYATHYTNCARATHGTNCAYGGNYTNYTNACNTCNAGYGGNGARTTY TTYYTNGGNATHGTNGARAAYCCNTAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATHACNYTNTAYTCNYTNGAYMGNCCNTCNGAY AARGCNAARGTNMGNYTNMGNGARATGYTNTCNTCNGARAAYGCNGTNGAYMGNTGGGCN GGNGCNCARTGYYTNGCNCAYTAYGGNGARTGYGAYTCNGAYGTNGTNGCNGARATHATH AARCARATHYTNGAYTCNGARTCNGCNATHAARCAYGARCARGGNATGGCNYTNYTNGCN AARATHAGYAAYAGYAGYACNYTNGTNCAYTGYATGGTNGCNGARCARYTNAAYAGYAGY AGYTGGMGNTAYMGNGTNATHGCNTGYAARATHYTNCCNATGYTNTTYGGNTCNATHAAY MGNGAYATHACNCARAARYTNTCNGARYTNATGTGGCAYGAYTGGCAYGTNGARGTNMGN AARGCNGCNGCNCARTGYYTNGGNAARACNAGYCAYGGNMGNGAYGTNCAYGAYGAYATH MGNGAYMGNATHYTNAAYGGNACNGARMGNACNAARATGGARGCNATHAAYAARYTNGGN CARYTNGGNATHATGACNGCNAARYTNYTNCCNGCNTTYYTNAARTGYTTYTCNGAYTCN TAYGTNTCNATHMGNTGYGARGTNTGYATHACNTGYGGNAAYYTNCARATHAARGARGAY CARGTNYTNGARCAYYTNATHCAYYTNGCNACNTTYGAYCCNATHTGGAARGTNAARGCN YTNGCNATHCARGCNYTNGGNAARATHGGNGARATHAAYGARGAYATHAARGARTGYYTN YTNTGGGCNATGMGNTAYGARGARAARCCNGGNGTNMGNGCNGARGCNTGYCAYTCNYTN GTNGGNYTNAAYGTNCARGAYGARGAYGTNATHGARATHYTNCARGAYMGNYTNYTNGTN GARTCNAGYCARYTNGTNMGNGARGARATGATHGARGCNYTNTCNGGNTTYGGNTAYAGY ACNTCNGARGAYATGGAYACNGTNGCNCARATHAARGCNGARGTNMGNAARYTNTGYACN MGNAAYATHATHGCNTCNCARGTNATHGTNAAYGARAAYGAYGAYACNAARMGNGARCAR YTNAARMGNATGGTNTGYCARACNGARAARGAYATHGARATGYTNAAYGARMGNAARGAR ATHATHYTNMGNMGNATHMGNTCNCARGCNMGNAGYAAY---------------GAYAGY GTNAGYTCNTCNCCNCCNCCNMGNACNTCNACNCCNYTNCCNAARGTNAARATHGGNTCN GARAGYAGYAGYACNACNCCNGARCCNGTNAGYMGNGARGGNACNGTNTTYACNCCNTCN GCNGAYAARGARYTNGARGCNATHYTNAAYCARGAYGARGARGTNGARAGYGTNAGYGGN TCNACNAGYGGNAARTCNMGNCCNGTNACNGAYGGNTCNYTNGARYTNGARACNCARGAR GARAAYGAYGARAAYYTNAARGARGARGARGAYGAYAAYGTNAARGTNATHTCNMGNATH ACNGTNACNAARGTN---------------GAYGAYAAYGTNAARGARGARCARAAYAGY ACNAGYAAYCARYTNGAYAARCCNAAYCARYTNGAYYTNCCNAARAGYCARGCNGGNTTY YTNACNCCNATGGGNTCNGTNGCNGAYTTYAARGGNTCNMGNYTNACNYTNAGYCARTTY TCNGGNAARMGNTCNATHATHAGYMGNGAYAGYATGMGNGARMGNGARAARYTNAAYGCN GARGTNAAYACNATHTAYGCNGAYYTNAAYGCNMGNTAYGCNGAYATGATHCARCAYYTN GCNAARATHGAYAARGGNYTNAAYACNAARGGNTCNTCNGCNGARTCNAGYACNGTNGAY AGYYTNAAYGTNTCNMGNGTNGGNTCNAAYCAYATHGCNMGNYTNAGYCAYCARGARATH GTNGAYACNATHAARGARYTNGARGCNATHCAR------TCNGCNMGNCARGARAARGAY TGYCARGCNGARYTNGARGAYAAYAAYAAYCAYAAYGGNGAYYTNAAYGGNAAYATHGAY GTNGARGGNGAYGARAAYYTNACNATHGAYGARGARAARGARGCNGTNGAYGAYCCNAAY ACNGARTGGAARTCNTTYGTNGAYACNYTNTCNCAYGAYAAYACNGARGAYAAYGARACN ACNTAYCCNTTYTGYGARGARAAYGGNATHTCNYTNATHAGYACNGAYGCNAAYACNGAY GAYCARAGYTCNGARGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYAAYATHMGNGAY---GTNAARGARGAYGTNATHCARATG ATHAAYGARYTNGCNGAYTTYGARGARATGTCNGGNMGNGTNGARAAYACNCCNAGYGGN YTNMGNCAYGAYATHTTYGGNGARCCNAARMGNTGYTCNTGYYTNGTNGTNGARCAYAAR GARAAYAARGARYTNGGNYTNGTNGGNTTYGCNATHTAYTTYCCNGCNTAYTCNACNTGG CARGGNCCNTTYYTNCAYYTNGARGAYYTNTAYGTNAARCCNGAYTTYMGNGGNTGYGGN ATHGGNAARMGNYTNTAYCARGCNGTNGCNCARATHGGNATHGAYATGGAYGTNCCNMGN YTNGARYTNGAYGTNYTNGAYTGGAAYAARAARGCNAARGAYTTYTAYGARAARGTNGGN AAYATGGAYATGACNGARAARGARTCNTGGCAYAARATGMGNATGYTNMGNGCNGARATG GARAARTTYGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG TCNGCNACNATGTAYTGGGGNGARATHCCNGARATHTCNGAYACNGAYTCNGGNATHGCN GCNYTNGARMGNGARCARATHACNMGNCCNAARCCNATGGARGTNGARGGNCAYYTNYTN CAYCARCCNTCNAAYMGNCAYCAYCCNCCNACNAAYGARYTNYTNTCNAGYGARCAYTTY AARATGGAYCCNGTNGTNYTNCAYACNATHMGNYTNYTNCARCAYATHAARAARGTNMGN GCNGCNGTNGARGTNYTNCARCARGAYATHAARTCNGAYACNGARCCNACNAGYATHAAY GTNGGNCCNATHCCNGARTAYGAYGGNCCNCARATHAARGAYMGNTCNMGNCARAARTAY TTYYTNCARAARGARTAYGARAGYGAYTTYGTNAARGGNGTNGCNAARCCNCARCCNCCN ATHGAYGAYGTNACNTGYMGNMGNYTNYTNMGNMGNTCNACNGCNGCNATHTGYGCNCAY YTNTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYGTNGAYTTYGAYAAR YTNCCNTGGACNGAYGAYTTYYTNTCNYTNGCNTCNTGYGAYTTYTAYCARTCNTTYATG TCNCCNGGNGTNAARTGYATHCCNGTNAAYGARGAYGGNATHYTNGGNACNYTNTTYYTN CCNGARGGNGAYGGNCCNTTYCCNGCNGTNATHGAYATHTTYGGNYTNACNTCNATGTAY CCNGGNCAYMGNTCNGCNYTNYTNGCNTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATHCCNYTNAARCARGAYYTNGAR ATGAARGTNAAYTGGGCNGCNTCNCCNAGYACNGCNCCNAARCARGAYACNAGYAARCAY TTYCAYGTNTTYGTNGGNGAYYTNAGYTCNGAYATHGARCARCAYCARYTNMGNGAYGCN TTYGCNGCNTAYGGNGARATHTCNGAYTGYAARATHATHMGNGAYCCNGCNACNATGAAR TCNAARGGNTAYGGNTTYGTNTCNTTYGTNAAYAARGCNGARGCNGARTTYGCNATHTCN AGYATGAAYAAYCARTGGYTNGGNACNMGNCCNATHMGNACNAAYTGGGCNACNMGNAAR CCNYTNGCNCCNGTNGCNAARGARAAYGCNAARCCNYTNGCNTAYGAYGARGTNTTYAGY CARTCNAGYTCNACNAAYTGYACNGTNTAYTGYGGNGGNGTNACNAAYGGNYTNACNGAR GARGTNATGMGNAARACNTTYGCNCARTAYGGNACNATHCARGARGTNMGNGTNTTYAAR GAYAARGGNTAYGCNTTYATHMGNTTYAGYACNAARGARGCNGCNACNCARGCNATHTGY GGNATHCAYGGNACNGCNATHAAYGARCARGTNGTNAARTGYTCNTGGGGNAARGARTCN AAYGARTCNAGYCARACNAAYCARCARTCNAAYAGYCCNCCNGTNGTNATGGTNCCNTCN CARCARCARCARCCNATHGCNGCNAGYCCNGCNGCNGCNCCNTAYGGNCAYCARTTYTAY AAYATGAAYTAYTAYCAYGGNGCNCCNTAYGCNGCNGGNACNCCNGCNTAYCARAGYACN GTNCCNACNCARGGNCARTTYATHCCNGCNTCN---GGNCARTGGCCN---AGYTAYTCN ACNTAYCARGCNTAYGGNAGYATGAAYGTNCCNGTNGGNGGNTAYGCNGGNYTNCARATG CARCCNGGNAGYCARCARCARCARTTYACNGGNCARACNCARGGNATGGTNGGNTAYCCN ATGCARCARGGNATGTCNMGNTCNAAYGTNMGNTAYGARGTNYTNCCNTCNGARGARCAR AAYGTNGCNGCNGARCCNGTNGARATGGCNATGGTNGTNCCNCCNCCNGGNTAYTCNGAR ACNGCNGTNATGGARCARAAYGGNGAYGAYCCNGCNTTYGGNCCNGCNAARYTNCCNAAY TAYGARGARGCNACNACNYTNCCNACNTAYGARGARGCNGARMGNACNAARYTNGARCAR GARACNTCNGGNGGNAAYACN---AAYGAYTGYGARTCNGGNMGNYTNACNTCNYTNGAY GGNATHAAYGARACNAAYATHGGNACNGAYGGNATGTTYATHTGYACNTTYNNNATHTCN TTYYTNTTYAAYTGGYTNGGNTTYYTNYTNTCNYTNTGYYTNTCNAAYACNATHGCNGGN MGNTGYGGNGCNYTNTCNGGNYTNGGNYTNTCNATHGTNAARTGGGTNGTNATHGCNAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNCCNGTNATHGTNTCNCCNTCNATG AGYGGNTCNTTYTCNYTNCCNTTYYTNTTYAARGARGGNGTNAAYAGYGTNGAYMGNGCN ATHGCNTTYGTNCCNGTNGCNCCNGTNAGYACNAGYCARTTYGTNAARCAYTAYTCNGAR AGYCARYTNCCNACNATGATHGTNTAYGGNACNAAYGAYGAYMGNATHGGNACNGTNAGY AAYAARGAYYTNGGNCAYYTNCCNMGNGGNCARTAYGCNCCNATHCARGAYGCNGGNCAY GCNTGYTAYATGAAYAAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN ACNMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GCNGAYYTNTCNAARYTNGARTAYACNACNATGTGYATHAAR GARGCNATGMGNTTYCAYACNGTNGTNCCNTTYATHGARMGNATHYTNAAYGARCCNYTN GARYTNGAYGGNCAYAARATHCCNAARGGNACNYTNGTNGCNGTNAARYTNTGGGAYYTN CAYCAYAAYCCNCAYGTNTGGGAYMGNCCNCAYGARTAYGAYCCNGARMGNTTYAAYGCN GARAAYTCNYTNAARATGGAYCCNTTYCARTTYYTNCCNTTYTCNGCNGGNTCNMGNAAY TGYATHGGNCARAAYTTYGCNATGAAYGARATGMGNATHATHGTNTCNTCNGTNATHAAR AAYTTYAARYTNGARATHGAYACNACNGARAARGCNMGNAARTTYTAYGCNGTNACNATH MGNACNGARAAYGGNGCNAARGTNTAYGCNACNCCNMGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNGAYATGACNAAYMGNGAYCCNAAYAAYYTNAAYGAYCAYGTNAAR GTNGCNTTYGARGARGTNATHGGNGARCCNGAYGGNCARCAYTCNATHGAYTGYGTNTGG AGYAAYTCNTAYAARTGYTTYAAYTGYTGGAARTCNTGYTGYTAYAAYYTNYTNACNATH TTYTGYGCNATHCCNATHTCNATGTGYTGGGGNTGYGARTTYGCNTAYATHACNTTYYTN CAYGTNTGGGARGTNACNCCNTGYATGMGNGCNTAYATGATHCARTGYGGNTGYATGCAR AARTTYTAYGGNACNTGYYTNCARTGYTGYATGCARCCNTGYTTYGARGCNATGGGNTTY TTYTTYAAYAAYATHAARGTNACNAAYYTNAGY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AGYAARTCNTTYTCNGARATH GAYAAYYTNTCNGAYTTYTCNGTNTAYAARGARTGGMGNCCNMGNTCNCAYTCNYTNACN MGNAARCAYAARAGYTGGGGNAGYGAYYTNGAYACNACNTAYAAYTCNACNTTYGTNTCN AARGGNAGYCAYTCNGAYYTNTCNMGNYTNACNCARTCNGTNGGNACNCCNCAYAARGAY TTYACNGGNACNAGYGTNGAYGTNMGNAGYGCNYTNCCNGAYACNAAYGARYTNTGYMGN MGNYTNGARGAYAARATHAAYAGYYTNACNMGNATGGGNGGNAAYYTNCARAARGARAAY MGNGARATGGCNAGYYTNATHGAYMGNCARGGNGARAARYTNGAYACNGTNAARYTNATH GARCARAARGCNMGNGGNTCNMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGAAYAARCCNGGNGAYCAYGTNYTNYTNTTYCAYTGYTCN CARTTYGARYTNCAYGTNGGNYTNCCNGGNYTNGGNGTNAAYGTNGARCAYGTNACNCAR CARGTNACNAARGCNAARGARAARGCNGARGCNATHYTNGGNAARGCNATGGAYGTNYTN AARGCNAARGARATHAARGGNTAYATHGTNTGYYTNAAYCARGAYAARGCNCAYGAYGCN ATHYTNACNACNGCNAARGAYGARAAYGTNGAYCAYATHGTNATGGGNACNMGNGAYYTN GGNGCNGTNMGNMGNGCNTTYGTNGGNAGYGTNAGYACNGARGTNGTNMGNCAYGCNACN GTNCCNTGYACNATHGTNAARTAYCAYGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AGYMGNATHATHTGGGTNGAYYTNGARATGACNGGNYTN GAYGTNGARAAYGAYMGNATHYTNGARATHGCNTGYYTNATHACNGARAARGAYYTNAAY MGNGTNGCNGARGGNCCNAAYYTNATHATHCAYCARAGYGAYAGYGTNYTNGAYGGNATG AAYGARTGGTGYGTNCARCAYCAYGGNGARTCNGGNYTNACNGARGCNTCNMGNAARTCN AARATHGAYATHAARGAYGCNGARAARATGGTNYTNGARTTYGTNCARCARCAYACNTCN AARGGNAARTGYCCNATHGGNGGNAAYTCNGTNGGNACNGAYAARCARTTYATHGCNAAR TAYATGCCNGARYTNGCNGARCAYYTNCAYTAYMGNATHATHGAYGTNAGYACNGTNAAR GARYTNTGYMGN---------------------------------MGNTGGTAYCCNGAY GARTTYAARGCNGTNCCNGCNAARAARYTNAAYCAYMGNGCNATGGAYGAYATHMGNGAR AGYATHGARGARYTNMGNTAYTAYCARCARGGNATHTTYAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CCNGTNATHGCN TCNAGYGGNATHGAYTAYAAYATHAARGTNTGGTCNCCNTGYGARGARGARTCNCARTTY GAYCCNGAYGTNGCNCAYATGATHATGCARMGNAAYGARYTNATGYTNGTNGARACNMGN GAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNYTNTAYCAY---CARGARAAYATHCCN GAYATHMGNGARTTYTCNATHATHGAYGAYYTNAARMGNCAYTAYAGYYTNACNTGYYTN GCNGTNTGYGGNATHYTNACNTGGYTNCCNATHGCNGTNATGYTNACNYTNCARAARTCN GGNGTNCCNGTNAGYGARGCNACNYTNGTNTAYTCNAAYATHGCNACNTCNYTNCCNTGY YTNYTNAAYCCNYTNYTNTAYAGYYTNGTNYTNGCNMGNTAYMGNGARGGNTAYAARGTN ATHYTNGARMGNTGYTGYMGNAARAAR--------------------------------- ------------------------------------------------------------ ---------------------------------------GTNTTYTTYTCNGTNTTYGGN CCNGTNATGAGYMGNCARATGTGYTAYACNTGYCARTTYGTNYTNAAYGGNCCNGGNATH GARTGYGTNACNGAYCCNYTNGARTGGAARGGNGGNGARCCNMGNATGAARTGYCCNAAY AARTGYACNATHYTNGCNGARTTYGAYGCNACNACNGGNGAYCCNACNTTYTTYCAYMGN GGNTGYGGNGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GCNGTNGTNGARTTYTCNCCNTTYCARAAR GTNCCNAARAARAARCCNMGNMGNGTNGAYTCNAARTGYGGNATHYTNGARCARGAYTCN GAYTAYAARAARTTYYTNGARATHYTNGCNAAYCCNCCNGARCCNCCNTCNATHTCNYTN GAYGCNATHGTNGARGARGTNGARGCNAARGARYTNMGNYTNGCNAARATGGGNTCNATH AARACNAGYACNCCNYTNYTNGARTAYYTNAARMGNMGNAARGARGARAARMGNATGAAY ATGGTNAARYTNMGNGAYGARMGNMGNMGNGGN---GCNMGNGAYMGNGAYTAYGAYMGN MGNMGNTCNGCNAARGAYGAYYTNGAYAAR------------------------------ ------MGNGAYMGNGAYMGNCARAARGARMGNGAYMGNMGNMGNGARMGNGARAARGAR MGNTCNMGNGARAARGARAARGARMGNAARMGNGARMGNGGNGGNGGNGGNMGNGAYMGN ---------GAYMGNMGNCCNGARAGYCAYGGNAGYAARCCNGARGAYGAYGARAAYCCN AARCCNATHATGYTNYTNAARAAYCARGAYMGNGARGGNCAR------GGNAARGARCCN CARTCNAAYTCNCCNTCNAAYAARTCNMGNAAYGTNAARGARGARGTNGARGARAGYAAR TCNGGNMGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CCNGARAARATHMGNGGNGGNGGNGARGTNTTYAARTTYCCNTGGACNGCNTAY TCNAARGTNCARCARTTYCCNTTYAARTTYTAYTGGAARCAYGGNMGNYTNTTYMGNTAY TTYTTYTAYACNGCNGGNATHGTNGTNCCNYTNATGYTNAARYTNACNAARGCNACN--- ------------------------------------------------------------ ------------------------------------------------------------ YTNGTNCCNGTNACNGGNACN---CCNMGNTCNGAYGARCARCCNMGNTTYYTNGCNCAR CCNYTNGGN------ATGCCNYTNCCNMGNCCNGCNCARCCNTTYATHYTNGCNGCNCCN MGNYTNCCNCCNCCNACNGTNGTNGCNTCNAGYCARGCNAAYATGAAYGGN---GCNCCN CCNCCNYTNGTNTCNCCNCCNCAYGARGCNACNGGNYTNGTNTAYAAYCCNTAYGCNATG AGY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNAARGARAAYCCNMGNCAYGCNAARTTYATHMGNYTNATHTCNCCNGCN CARYTNCARMGNYTNYTNACNATHGTNAARGAYAARATHAAYGGNYTNAGYYTNGARGCN AGYATHGCNMGNAAYAAYGARATGGAYAGYYTNAAYCCNGARGARAAYYTNAAYAARGTN GAYGARGARACNYTNMGNMGNAARAARYTNGTNATGAAYACNTCNTTYGARAARAAYCAR AARAARYTNGGNGAYCCNGAYTTYGARTAYAAYGTNGARGTNGAYTTYGARGCNGGNGCN GTNGARACNAGYGGNTGGGAYTCNGAYAAYTCNGAYATGGAYTTY >iodinea YTNYTNATHACNCCNYTNTTYYTNGGNGTNGCNYTNGCNGGNTAYGAYCCNTAYAAYGAY YTNGCNCARTAYTAYMGNATGCARYTNYTNGCNGAYGCNTTYGGNGAYTAYATHCCNGAR AAYYTNCARYTNGAYAAYAAYGAYGTNGAR------ATHMGNTCNTAYTGGCCNGARTTY ---------------GCNGCNTCNYTNGARGAYGGNGCNAARTCNGAYAAYGTNTAYGGN TCNCARGCNTAYAGYGGNGCNCAYATHMGNGAYCARGARCAYATHGARCAYAGYGCNYTN CAYGGNTAYCARTCNGTNTCNGGNGGNACNGCNGARGGNCCNGCNAAYAAYAARATGCAR AARAGYGAYAARCCNYTNCCNGCNTAYTGYAAYCCNCCNAAYCCNTGYCCNYTNGGNAAR ACNGCNAARGAYAAYTGYGTNGARGAYTTYGARAAYTCNGCNGARAAYAAYAARAARYTN YTNAGYGARCARGAYTGYCCNTGYGAYACNGARCAYATGTTYAGYTGYCCNGCNGGNAAR GARACNGTNTCNTCNAARGGNCARTCNGGNTAYCARCARACNYTNAAYAARGTNATHGAY CARYTNAGYAARATGGGNGCNGTNGAYGAR------GARAAYGGNGGNYTNYTNAAYCCN GARATGAARMGNGTNAARYTNGTNGCNAARAARTCNCCNCAYATHATHCAYAARMGNTTY GARAARCCNGAYACNGTNAAYCCNTAYYTNGTNGGNACNCCNATGGGNATHGCNGCNAAR AARAAYCAYGARAAYTCNCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNAAYGAR MGNAARMGNATHGCNATGGAYMGNTAYATGCARGCNYTNGARAGYGGNGAYGTNGCNATG GTNAAYAARTAYYTNCAYAAYTAYATHAARGCNGARGARAARGAYMGNATGCAYACNGTN AAYCAYTTYAAYCAYATHMGNAAYTCNAAYCCNAARGARGCNYTNMGNATHCAYMGNCAY ATHATHMGNCAYYTNCARACNTCNGARYTNMGNATHGAYCARGCNATGGARATGYTNACN CAYTAYCCNCARYTNGARGCNACNGTNMGNCCNGARATHGARGARTTYYTNAARMGNTTY AAYGARATHGCNACNAGYATHAARAAYGTNGTNYTNCCNGTNCCNGTNGTNGARGARGAY ------------------GAYGARGAYAGYGARGARGARTCNAGYGAYAGYAGYGAYTCN GAYGAYAAYTAYTCNTCNGAYGARCCNAAYAARTAYGAYACNAGYAGYGARGARAARGAR GARACN---------------------------------------GGNCARGARACNTAY CAYGARGTNGAYTCNACNGTNATHGAYGAYGARGTNCARGARGAYGARCAYAGYTAYGAR MGNAARCARCCNTAYGCNGCNAAYGCNATGTCNGAYACNCAYAGYGCNAGYCAYGGNYTN AARTCNGCNGCNACNTCNGGNTCNCARYTNGGNAGYACNGTNGGNATHGCNYTNGGNAGY GTNAGYGTNTTYGTNATHATHGTNGTNGCNGTNATGATGATHMGNCAYAAYAARCAYMGN CARACNGTNTCNCAYGGNTAYGTNGARGTNGAYCCNTCNGCNTCNCCNGARGARMGNCAY YTNGCNAAYATGCARATGAAYGGNTAYGARAAYCCNACNTAYAARTAYTTYGAR------ ---AARGAYAARYTNTAYMGNCARYTNACNATHGARATHAARGGNCAYGAYCCNGCNGTN ATHAAYAGYTAYCARAARTTYACNACNYTNGCNGCNGARCAYYTNGGNGTNCARATHGCN AAYATHTCNGARCCNCCNMGNGTNATHACNMGNAARAGYYTNYTNAARTCNGTNTTYATH TTYAARAARCAYCARCAYCARTAYGARACNMGNACNYTNTTYMGNGTNTTYGARTTYAAR CAYYTNACNGARTCNACNGCNAGYACNTTYYTNGARTAYATHCARMGNAAYYTNCCNGAR GGNATGGCNATGAARGTNACNAARCAYGARYTNCARCARATHCCNGAYCAYYTNAARCCN CCNGARCARTCN------------------------GAYTAYTTYAAYGTNATGYTNGGN TCNCARYTNYTNTAYAARTTYGARMGNCCNCARTAYGGNGARATHYTNGCNGARTAYCCN GAYAARCCNGTNTCNAGYATHTAYGGNGCNACNCAYYTNYTNMGNYTNTTYGTNMGNYTN GGNGCNATGYTNGCNTTYACNTCNYTNGAYGARMGNACNGTNCAYATHYTNYTNAAYCAY GTNCAYGAYTTYYTNAARTAYATGTCNAARAAYGGNCCNAGYYTNTTYAARACNTCNAAY TAYGARATHGCNACNCCNGAYTAYCAYMGNAARGCNATHMGNYTNATHGAYGCNATHATG CARGAYTAYAAYCCNGCNTCNMGNCCNGTNTAYAAYGCNTCNAARACNGTNACNGTNAAR TTYGGNATHACNYTNACNCARATHTCNGAYATGGAYGARGTNAAYCARGTNYTNACNYTN AAYGTNTGGYTNGARCARGARTGGGTNGAYGARMGNYTNACNTGGGAYCCNAARGAYTAY AAYAAYYTNCAYAARYTNMGNATHCCNTGYGARAARYTNTGGYTNCCNGAYATHGTNYTN TAYAAYAGYGCNGAYGAYTTYACNGCNGGNTAYATGAAYAGYAARGCNATGGTNGGNTAY GAYGGNAAYGTNTTYTGGCCNCCNCCNGCNAARTTYMGNAGYTCNTGYACNATHGAYATH ACNTAYTTYCCNTTYGAYGAYCARATHTGYGARYTNAARTTYGGNTCNTGGACNTAYGAY GGNTTYCARGTNGAYATHACNAAYMGNTCNGCNAARGTNGAYYTNCARAAYTAYGTNYTN AGYGGNGARTGGGARYTNATHAARGTNGGNYTNAARMGNACNGARGTNACNTAYGCNTGY TGYAARGARCCNTAYCCNGAYGTNMGNTTYACNATHGTNATHMGNMGNAARACNYTNTTY TAYYTNTTYAAYATHATHTTYCCNTGYYTNTGGYTNACNATHYTNAGYYTNYTNGGNTTY TGGYTNCCNCCNGAYTCNGGNGARAARATHACNYTNGGNATHACNGTNYTNYTNGCNTTY TCNGTNTTYATGYTNYTNATHGCNGARAGYATGCCNGCNACNTCNGAYTTYGTNCCNYTN ATHGGNATHTAYYTNACNGTNACNATGGGNATGACNTCNYTNTCNATHATHYTNACNGTN TTYGTNYTNCARYTNCAYCAYATHGGNCCNCAYCARAARCCNGTNCCNMGNTGGYTNMGN AGYYTNGTNTTYAAYTTYYTNGCNMGNYTNGTNTGYYTNTGYTGGGARYTNYTNGGNACN AARTGYATHMGNAGYGTNATHTTYTAYACNTGYTGYCCNGARCCNTTYATHGAYGTNACN TTYTAYATHYTNATHMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TCNAARCARMGNTGGATHCCNYTNGAR TCNAAYCCNACNATHYTNAAYAARTAYGTNCAYGGNYTNGGNATGGAYAARAGYTGGAAY TTYGTNGAYGTNTAYGGNYTNGAYCCNGAYYTNYTNGCNATGGTNCCNCAYCCNGTNGCN GCNGTNGTNYTNYTNTTYCCNGAYGCNAARGCN------------GARGAYGCNATHGGN GARTAYATGAARGARAGYCCNGARGAYYTNTAYTAYACNAARCARACNATHGGNAAYGCN TGYGGNACNGTNGCNYTNGTNCAYGCNYTNGCNAAYAAYCARGAYAARATHACNTTYGAR GARAAYAARCCNTTYGCNAAYTTYYTNAARGCNACNAARTCNATGAAYCCNGARGAYAAR GCNAARCAYYTNGARGARGAYATGCARATGGGNGCNGCNCAYGARGAYTGYGCNCARGAR GGNGTNACNGCNGTNCCNGCNGCNACNGAYAARGTNAARTAYCAYTTYATHGCNYTNGTN CAYTTYGGNGGNACNYTNGTNGARYTNGAYGGNMGNAARGAYGGNCCNGTNAGYCAYGGN ACNACNACNGCNGAYAGYYTNYTNGARGAYGCNGCNAGYGTNGTNAARAARTTYATHGAR AARAGYCCNTAYATGTCNGARMGNAGYGCNATGYTNAARAAYGAYMGNMGNTCNAGYATH GGNCARCARYTNTCNYTNTCNGARAAYGARAARYTNGTNTCNGGNTCNATGGTNAARGAR AARGCNGCNYTNATGAAYGARAGYMGNCARGGNGGNACNCCNTAYTTYCCNGCNAGYAGY TTYTAYGTNTCNAARCCNCARATGGARAARACNCAYYTNTTYAARYTNATHAARTCNATG CCNAARGGNGCNGCNYTNCAYYTNCAYGAYCARGCNATHACNAGYYTNGAYTGGYTNGTN AARAAYGTNACNTAYMGNGAYCAYYTNTAYATGTGYGTNAAYAARGARTCNYTNATGATH TTYAARTTYTTYAARACNCCNCCNGCNGAYCCNTAYTGYATHTGGACNTCNGTNCARAAR GARMGNAARAARGCNGGNAAYCCNGAYGAYTTYGAYAAYAGYATHAARMGNAAYYTNAGY YTNYTNTCNACNGAYCCNYTNGTNACNTAYCCNACNATHACNAARGTNTGGCAYMGNTTY ATGGGNTAYTTYGGNCARGTNTAYGGNATGATHTTYTAYGCNCCNGTNTTYAARGAYTAY TTYCAYCARGCNYTNAARGARTTYCAYGCNGAYAAYGTNCARTAYTTYGARYTNMGNGGN ATGATGGGNGGNATHTAYGAYYTNGAYGGNGCNACNTAYGGNATGGARCAYGGNYTNAAY ATHTAYMGNACNGTNACNCARCARTTYGTNAARGARAAYCCNACNTTYYTNGGNGTNAAR TTYATHATGTCNGGNYTNMGNAAYAGYCARACNAAYGCNATHYTNAARGARATHAARGAY ACNGTNATGYTNMGNGARAARTAYCCNAGYGAYYTNYTNGGNTAYGAYYTNGTNGGNCAR GARGAYCCNAAYTTYTCNYTNYTNCAYTAYMGNGAYGARYTNYTNTAYCCNAGYCAYATG ACNCCNGCNCARAARYTNCCNTAYTTYTTYCAYGCNGCNGARACNAAYTGGCARGGNACN GAYACNGAYTAYAAYYTNATHGAYGCNATHYTNYTNAAYACNACNMGNATHGGNCAYGGN TTYGGNYTNGTNAARCAYCCNAGYYTNGTNGARAARGTNAARGARGARAGYATHGCNATH GARGTNAAYCCNATHTCNAAYCARYTNYTNGGNYTNGTNAARGAYYTNMGNAAYCAYGCN ATGGTNCCNYTNATGGCNGAYAAYYTNCCNYTNGTNATHAGYTCNGAYGAYCCNGGNTGY TGGGARGCNGAYCCNYTNTCNCAYGAYTTYTAYYTNGCNTTYATGAAYATGTGYGGNGAR GAYGCNGAYYTNMGNTTYYTNAARCARYTNGCNYTNAAYTCNATHCARTAYAGYGCNATG AGYAARGCNGARAARGAYGCNGCNATGAARYTNTGGYTNTCNGARTGGAAYAARTTYATH GARACNGARGCNCAYACNAARGARACNATHGCNACNGTNTCNGGNAARCARGARCARTCN MGNGTNAARMGNGGNAGYTAYGAYATGYTNMGNYTNACNMGNGGNYTNAAYATGYTNMGN YTNGGNAARMGNGCN------GTNGARCCNTCNAAYCARGARGARYTNTTYACNYTNGAR GAYAAYATHCCNGGNYTNCARGCNTCNGTNAAYGAYATHTAYCCNGARGARTAYTAYAAR GCNYTNGCNCCNAAYGARGAYATHTAYGAYATGGARCCNCAYAGYMGNTAYMGNMGNTCN ACNCCNTCNGAYCAYYTNATGGTNACNGCNGAYYTNATHGGNAAYGAYAAYTCNGGNATH TCNGAYGGNYTNAARATHGAYGAYGAYGAYGAYGAYGAYGCNTAYYTNATGTAYCCNGAR TGGGAYTAYGGNGTNGGNGAYGGNGGNGAYAARGTNTGGGAYGARAARGAYGGNGARGGN AAYGARGARMGNACNCCNTCNATGYTNATGYTNGGNAARMGNCARYTNGCNATGYTNMGN YTNGGNAARMGNYTNGAYGTNGGNGARGAYMGNYTNGGNAARMGNCARMGNGARAAYYTN AAYAGYGAYTTYACNGAYAGYGAYCARAARMGNACNYTNTCNATGYTNMGNYTNGGNAAR ---------------------------AARMGNAAYYTNAAYATGYTNMGNYTNGGNAAR MGN------------TAYCCNTTYGGNAAYAARAARYTNAAYATGYTNMGNATGGGNAAR ---------------------------AARMGNAAYYTNAAYATGYTNMGNYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYGAYMGNTAYAARCAYATHCAYAAYGCN ATGTAYTAYGAYYTNTGGATGACNACNGGNAARGCNYTNTTYTTYATHGCNTCNGTNTGG ATHYTNTCNGCNYTNATHTCNTTYYTNCCNATHCAYYTNGGNTGG--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GTNTTYYTNATHCARGCNTTYYTN TTYAARTTYCCNAAYATHGTNTGGACNGARATGAARAAYTAYTCNGGNYTNAAYGTNTCN AARGTNGTNGGNATGGCNTGGGARACNTCNATGATGACNCARGARGARMGNGAYAARACN ATGAGYCAYATHGCNATHTTYATHGAYMGNTGGYTNAARACNTAYTCNCARTAYMGNTTY AGYGCNATHACNGARTTYMGNGAYAARTTYTCNMGNATHATGTTYTGY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATHAAYATHYTNYTNATHGTNYTNGGNTCNYTNATHTGY GCNTCNTGYYTNCCNAARMGNTCNGCNGARGAYATHYTNCARGAYACNTCNGGNYTNGTN YTNGAYAARMGNCCNAARTAYATGGAYACNMGNMGNGAYYTNGAYGTNTTYAARGAYYTN GTNYTNATHAGYGTNCARGARYTNGTNGAYGARGGNMGNYTNGAYTCNTCNGTNYTNCCN GARGGN------GAYAARGARACNAGYAARCCNGTNGARAARMGNMGNTAYATGGGNYTN TGYATGCAYMGNCARGCNAAYCARTAYATHCCNTTYCCNTGYYTNMGNGCNGGNMGN--- ATGAARGCNGTNYTNTGYYTNGTNYTNATHGGNTGYGCNGTNTTYGCNGAYAAYTAYYTN TGY---CCNAARGARGGNGAYYTNTTYGARTGYTAYGARTAYGGNYTNACNGCNMGNGCN TGYYTNACNGAYGGNMGN------GGNACNTCNGTNATHTGYTCNAARTGYAARMGNAAR TGGGARTTYTGYGCNTCNCAYGGNAARTAYCARGARTCNAARCAYCCNGARMGNGAYTGY GGNGAYGAYTAYGARAGYACNCCNTGYACNAARGAYAAYTCN------------------ YTNGTNGTNGTNTGYACNTCNGCNYTNAGYTAYGCNTAYCCNATGTAYCARACNMGNATH CCNAAYGGNGCNGTNGCNCARCAYCCNTGYYTNCCNYTNATHGARTGGCCNGGNYTNGGN CAYTCNAGYCCNTCNGGNTAYAGYCCNYTNAAYGCNTTYGGNGARGCNTTYYTNGCNGCN GGNAAYCARTGGACNCCNGAYYTNTGYCARGCNGAYTCNGAYGGNGAYGGNGARTCNAAY GGNCARGARYTNGGNGAYCCNGAYTGYATHTGGMGNGARGGNGAYACNCCNTCNMGNACN ACNGCNATHACNCAYCCNGGNTTY---------------------ATHAGYACNATHGAY TCNAARCCNTTYGTNMGNGARGTNAARAAYGTNMGNTAYGCNGGNTTYYTNAARGAYYTN ATGGAYCARGTNGGNATGMGNGCNGGNTTYACNTAYGAYTTYMGNCARCCNGAYAARGCN GTNTAYGGNTCNGARMGNTCNGAYGGNTGGACNGGNGTNATGGGNGAYGTNATHAGYGGN AARGCNGAYGTNGGNGGNCARYTNACNGTNACNCCNACNMGNGARGAYGCNGTNGAYTTY ACNAARCCNTTYYTNTCNGAYGGNGTNAAYYTNYTNGTNAARAARCCNTCNTGGTTYGAY YTNGGNYTNGGNTAYYTNGTNMGNCCNYTNTCNTCNGAYTAYTGGATHATGYTNYTNGTN GTNYTNYTNYTNATHGGNATHGTNTTYTTYATHATHGGNAARTTYAGYCCNTAYGARTGG GGNAAYGTNGCNGCNGAYAARGAYCCNMGNGGNGCNAARAAYAGYTTYACNYTNAARAAY AGYTAYYTNTTYGCNYTNACNACNYTNTCNTGGCARGGNTTYMGNGARGCNCCNAARTCN YTNTCNGGNMGNATHATGGCNGCNTTYTGGYTNYTNTTYGTNYTNTTYACNYTNATHGCN TAYACNGCNAAYYTNACNGCNTAYTTYCCNGARCARATHCCNGAYYTNCCNTTYAARACN TAYGARGARYTN---YTNGARTCNGAYATHGGNGTNATGGCNYTNGARTTYGGNGCNACN GARAGYTCNYTNMGNACNAGYMGNAGYAARACNATGMGNGCNYTNTGGGGNAARATGTCN AAYAAR------TTYGTNAGYACNGARGARGARGGNGTNAARMGNGTNAARTCNGARGGN TCNACNAAYGTNTTYTTYATGGAYACNMGNACNGCNGARTAYGCNAGYCAYGCNGAYAAR TGYGAYATGATGYTNTAYGGNGARACNYTNTTYCCNAGYTCNYTNGCNATGGCNGTNACN AARGGNTCNGTNTGGMGNGARAARATHAGYGCNGCNATHGARGARYTNMGNAGYYTNGGN ATHATHGAYGARYTNAARGAYAARTAYTGGMGNTTYGGNGGNAARTGY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNGTNACNYTNTCNYTNTTYGCNGGNACNACNTGYGCNGTN TTYTAYATHCCNGGNTCNGTNGTNAGYTAYCCNAARATGGGNAARMGNGCNTTYTAYACN AAYGCNACNGGNAAYMGNTAYCCNYTNATGGGNMGNMGNTCNTCNCCNACNAAYGCNCAR GAYTCNGGNAAYAGYCAYGCNGARGGNGTNATGGGN---GCNATGATGCARGAYAGYAAY GARTAYAAYAARMGNGGNGTNTTYACNCARGGNCCNCAYMGNAGYTTYCCNMGNGTNGGN MGNTCNGGNCARGCNAGYGARACNTCNGAYGCNACNGTNACNGGNAARATHMGNAGYGAR ATHYTNAARGARATHMGNAGY---YTNGTNGARGAYCCNAGYGGNCAYTCNGGNGARAGY AGYAGYYTNTCNYTNAARGGNATGAGYGCNCARYTNCCN---CARTTYYTNTTYYTNATH TTYGAYGARGAYGGNGAYAAYCARYTNAGYAARGARGARTTYACNACNGGNGTNGCNAAR ATHATGGARCARAAYYTNYTNTGY------------------------------GAYAAR CCNGTNGAYGTNTCNGTNAGYYTNTCNYTNATHAAYATHAAYGARGTNGAYGTNAAYACN AARAAYGTNTAYYTNGAYGCNTGGATGTCNYTNAGYTGGAAYAGYGGNYTNACNTTYGAY CCNTCNAARTTYAAYAAYATHACNGAYGTNMGNGTNCCNMGNTCNGCNATHTGGGTNCCN GAYYTNGCNGTNTAYAAYGGN---GARYTNTCNYTNCCNATHAAYAGYTCNGAYAARGCN GTNGTNTTYAAYACNGGNYTNGTNTAYTGGATHCCNCARTCNAARATHMGNGTNYTNTGY GAYGCNACNGARGGNTCNGAYGTNGCNAAYGCNACNTGYGARATHAARATHGGNTCNTGG ACNTAYAGYGGNAAYCAYYTNGCNYTN---GGNGAYACNCCNAGYTTYGAYYTNAAYAGY TAYTTYCCNGGNTCNGCNTTYGTNGTNACNGAYACNTCNGCNAARAARGARAGYAARYTN TAYTCNTGYTGYCCNGAYACNTAYGARGAYATHYTNTTYTCNTTYACNTTYMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------YTNYTNAGYYTNGCN YTNGTNTTYGTNTAYAARGTNCCNACNATHTCNGCNAAYTAYGARCAYTTYTGYGAYCCN GAYTCNTTYACNMGNCARCCNYTNGGNCAYTGYGGNGAYCARYTNGCNGAYAAYATHAAY TTYYTNTGYGARCAYTTYTCNGGNGGN------TTYYTNGGNAARTAYGTNGTNAARMGN AGYCCNMGNAAYGTNGAYAARGAR---YTNAAYGAYYTNYTNGTNAAYAARAARGAYGCN TTYTCNTTYYTNGCNAARMGNCARAGYGTNCARAAYGTNGTNTGYGARTGYTGYATHAAY TCNTGYAGYGTNATGGARYTNYTNCARTAYTGYGARYTNCCNAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR MGNGGNATHCCNMGNTTYGTNGGNAARMGNGGNCCNCCNMGNTTYGTNGGNAARMGNGGN MGNCCNMGNTTYGTNGGNMGNMGNGGNGCNCCNMGNTTYGTNGGNAARMGNGGNGTNCCN MGNTTYGTNGGNAARMGN---------------------------AGYGAYAAYTTYGAY TTYAGYGAYTAYYTNYTNMGNYTNGARGCNYTNAAYCARAARMGNAARGCNCCNMGNTTY ATHGGNAARAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TAYAAYGAYTTYTTYGGNATHGCNTAYCCN YTNGCNAARCARGAYYTNATHGCNATHCCNAAYTTYGCNGCNGGNGCNATGGARAAYTGG GGNYTNATHACNTAYMGNGAYACNGARGTNYTNTAYGAYCCNAARGARTCNACNGCNTCN ACNAARAARMGNGTNGCNGARGTNGTNGCNCAYGARYTNGCNCAYCARTGGTTYGGNAAY YTNGTNACNATGAARTGGTGGAAYGAYYTNTGGYTNAAYGARGGNTTYGCNTCNTAYGTN GARAAYATHGGNGCNCARACNGTNGAYCCNAGYTTYCAYATGTTYGAR---TCNATGGCN TCNAAYGGNMGNMGNGCNYTNGTNATHGAYAGYYTNAGYTCNTCNCAYCCNATHGARGTN AARGTNAGYGAYCCNGTNGARGTNGARGCNGCNTTYAAYACNATHACNTAYAAYAARGGN TCNAAYYTNGTNCAYATGYTNAARGGNGCNATHGGNGCNGARGARTTYCAYAARGGNYTN AAYTAYTAYYTNAARGTNCAYGCNTAYAGYAAYGCNGARACNAARCARYTNTGGGARGCN TTYGARAARAGYCAYYTNGAYAARYTNAGYGTNGCNGAYTTYATGGAYACNTGGACNCAR CARATGGGNTAYCCNGTNGTNACNGTNACNMGNAAYAARGAYYTNATHTAYYTNACNCAR GARMGNTTYYTNYTNAAYAAYGAYTCNGAYTCNTCNAAR--------------------- TAYAGYTGGCAYATHCCNTTYAARTAYAARYTNTCNGAYAAYACNAAYGARACNATGATG GTNTGGATGAARMGNGGNGAYGCNTCNATHCAYYTNCCNACNTCNTCNACNTGGATHAAR GGNAAYGCNAAYAGYGARGGNTTYTAYMGNGTNAAYTAYGAYGCNCARGGNTGGAARGCN ATHATHGTNCARYTNATGAAYGAYCAYACNGTNTTYTCNGTNYTNGAYMGNATGAGYYTN ATHGAYGAYGCNTTYAAYYTNGCNCARTCNGGNMGNYTNGGNTAYTCNACNGTNYTNGAY YTNTGYAARTAYYTNGTNAARGARACNGAYTAYTAYGTNTGGCARMGNGCNTTYACNAAY TTYTAYTTYYTNMGNCAYMGNYTNTTYYTNCAYGARGTNTTYGAYGAYYTNAARGCNTAY ATHYTNCAYYTNGCNCARCCNYTNGTNGAYMGNATHGGNTGGGARCCNAARGARTCNTTY ACNCARMGNYTNYTNCARACNTCNATHATHTCNGCNGCNGTNTCNYTNGARTAYCARCCN GCNGTNCAYCARGCNMGNGGNTGGTTYCARAARTGGATHGAYAAYGARAAYGARYTNAAY AAYGAYATGMGNAAYGTNATHTAYCAYGCNGGNGTNAGYTAYAGYACNAARGCNGARTGG GAYATHGTNTAYGARMGNTAYATGACNAGYATHGTNCCNTCNAAYAARCAYATGYTNATG ACNGCNYTNTCNTAYTCNMGNGAYGCNMGNGTNYTNCARATHYTNYTNGAYMGNAGYYTN GAYACNAGYCARGTNAARTCNCARTCNACNGTNACNGTNYTNTCNGAYATHTCNGCNAAY CCNAAYGGNAARYTNTAYGCNTGGMGNTTYYTNMGNCARCAYTGGGAYCARYTNTTYGAR MGNTAYGGNTCNGGNTCNTTYACNYTNTCNAGYYTNATHAARAAYATHYTNGARCAYTTY AGYACNCARTTYGAYYTNGAYGARGTNACNTCNTTYTTYCARGAYAARGAYYTNGGNAGY GCNAARAAYGCNTAYCARCARGCNAARGAYGTNATHAARGCNAARATHACNTGGGARCAR CAYCAYYTNGCNTCNGTNACNGCNTGGYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GAYAGYCCNACNGTNAAYCCNGTNCCNGARGARATHCCNCCNGAYATHAGY GAYAAYCARCARGTNAAYGAYCARCAYGAYGAYCCNGARGARAAYGGNTCNACNATGGTN GARGARATHGARCCNTCNGCNGARATGTTYGCNAARYTNAARAAR---AGYGGNGGNAAR YTNGTNTAYGAYMGNGCNTAYYTNYTNGARYTNMGNGAYTGYTCNTCNTCNCARACNAAR CCNGAYGGNYTNCCNGCNYTNGAYATHATHYTNGAYAAYCCNCCNCCNTTYATGCCNMGN CCNTCN---GCNGGNCCNGCNGAYTTYACNCCNGCNTTYTTYCARACNGGN---ACNAAY CARMGNCAYGCNCCNCCNATHGGNAARAGYAGYAGYMGNGGNMGNTCNMGNCCN---GGN TCNGGN---ACNCCNMGNGTNATHAARAGYATHTCNATGTCNCAYGAYACNAARACNYTN CAYCARAGYGARAAYCCNTGGAARCCNTCNAARGAYAARGARGGN--------------- ---AARGGNYTNGARGGNGARATHYTNTTYATHATGAAYMGNYTNACNCCNACNAAYTTY GARAARATGGCNAAYGARATGAARCARYTNAAYGTNAARACNTAYAARGAYYTNCARTTY ATGGTNAARGTNTTYTTYGARAARGTNACNYTNGARACNAARTTYGTNCARGCNTAYGCN CARYTNTGYAARGTNATGTCNGGNYTNAARGTNACNCCNCCNACNGAYGGNAGYGTNAAR GARAAYATGGCNACNTTYMGNGTNGTNATGYTNACNAARTGYCARCARGARTTYGARGCN GAYAARTCNATHGTNTTYGARGAYCCNGARGARAARAARAARAARYTNGARGCNGARAAY CCNGARAARACNCCNGARMGNGAYGAYATGATHGARAARACNYTNTAYCAYATGAARYTN AARMGNATGAARTTYTAYGGNAAYATHMGNTTYATHGGNGARYTNTTYAARYTNAAYATG YTNACNGARAAYATHATGCAYGAYTGYATHTTYMGNYTNYTNAARGCNMGNGAYGAYGAY TCNYTNGTNTCNYTNTGYAAYYTNYTNACNACNGTNGGNMGNAAYYTNGAYATHGARAAR GCNAARCCNMGNATGGAYCARTAYTTYTCNCARATGGTNAARATHGCNGAYGARMGNAAR TCNMGNATHAARTTYACNYTNMGNGAYGTNATHGARYTNMGNCARAAYAAYTGGGTNCCN MGNAARGARACNACNGGNCCNAARAARATHGAYGARGTNCAYAARGAYTAYGCNCARGAR CARYTNMGNAAYCARTAYYTNGCNTCNCARCCNCCNCCNCCNMGNAAYGAYAAY---CAR CCNGGNAGYMGNMGNGGNAGYMGNCARMGNCARGAYGAY---AARACNAAYGARGAYGGN TGGAAYACNGTNAGYTCN---AARTCNGTNMGNATGATHGAYGCNTCNAARATGAARATH TCNAARAAYGTNATGGTNGAYGAYAAYATHCARYTNGGNCCNGGNGGNGGNGCNCAYAAR ---CCNGTNTGGAGYMGNGGNAGYCAYGGNGGNACN---CARCCNTCNCARGAYGAYMGN CCNGCNGTNGGNTCNAAYMGNTTYTCNGCNYTNGGNGGNGAYGAYGGNMGNMGNTCNTAY CCNMGNTCNCCNTCNMGNGGNGARGGNTCNGCNGGNMGNGGNYTNMGNCARGGNCARACN GCNGGNCAYGGNMGNGGNAARATHATGGCNMGNTCNAGYCARGARGGNGARMGNMGNGAY GCNATHGCNAAYGCNMGNTCNTTYATGGGNGGNMGNTCNCARAAYTCNAGYMGNGARAAY AGYTGGAAYMGNGAYGAYMGNMGNCARYTNATGGGNCCNMGNAGYTCNTAYGARMGNGAY AAYCCNATGACNMGNAGYGAY---------AGYGCNGCNCARGARTTYMGNGCNCCNGCN CCNCCN------GCNGTNAARCARATGTCNGARTCNGARATHGARACNAARGCNGTNAAY ATHYTNGAYGARTAYYTNAAYATHMGNGAYYTNGCNGARGCNAARYTNTGYATGAARGAR YTNGCNGGNCARAAYCAYYTNTAYYTNGTNGTNACNGCNTGYATHAAYAGYGTNYTNGAR AARAARGAYACNACNMGNCAYATGACNGGNGAYYTNTTYCAYGARATHGTNGGNAAYAAY ATHATHGCNYTNGAYATHTAYGTNAARGGNYTNAAYGARGTNYTNCARTAYGCNAGYGAY ATGGTNGTNGAYATHCCNACNYTNTGGAAYTGYYTNGCNCARGTNATHYTNCCNYTNYTN GTNGGNGGNTCNYTNCCNTGGTCNAARYTNAARCARGCNTTYACNCCNTAYYTNGAYAAY AARGAYGGNGCNAARYTNATGGCNTCNYTNYTNTCNCARTGYGTNGARAARCARGGNGAR AARCARGTNGTNCAYCARTGGCARAAYAGYGGNYTNAGYTGGTCNACNTAYYTNAARCAR GAYGARYTNAGYTCNTTYGTNGCNGAYAARAARNNNGAYTTY------------------ ------------------------ACNYTNGGNACNGGNAGYAAYGTNGGNATHYTNCCN GAYYTNGARGARATGATHCAYGCNAARGCNTCNAAYAGYGAYYTNATHTCNTAYATHGAR AARACNGTNTCNGGNAGYAARACNGAYTCNTCNTTYATHMGNGCNYTNACNACNGCNTTY GTNAGYTCNTCNATHACN---------GAYAARAARAGYGTNAAYGARGAYGTNATHAAR AAYCAYAARGAYGTNYTNCARMGNTAYYTN---GGNAGYAARGTNGAYYTNCARYTNCAR GCNYTNTAYGCNATHCARACNYTNATGGCNAARYTNGARCAYCCNTCNGGNGTNYTNYTN CARYTNTTYGARYTNTTYTAYTAYGARATHTCNGTNGARGARGARGCNYTNTAYMGNTGG GARAARTGYAAYGAYCCNCARGARCARGARAGYAARGGNACNTGYYTNATGCARGTNMGN CARTTYTTYACNTAYYTNMGNGARAAYGARGARCCNGAR--------------------- ------------------------------------------------------------ ------------------------------CCNGAYAGYTGGTTYGAYGAY---YTNGAY CCNGAYATGTCN---GGNGAYCCNYTNGGNGAYGAYAGYATGGARGCNTTYATHAAYYTN GAYAARTTYYTNAAYGGNAAYTCNTTYTTYGAYGAR------GAYGGNAAYYTNACN--- GTNCCNGAYGARGCNGARGTNACNCCNGTNATHAAYTTYACNCCNAARACNGARGTNGTN GTNACNGARGAYGAYCARGAYTTYYTNYTNTCNTCNGTNCARTCNACNAARACNGCNGCN AARCCNTCNMGNAARMGN---------ACNGTNAARGGNGGNATHAARACNAGYYTNTAY GARATHCCNCCNACNTCNGTNATHCCNGAYATHTTYCARGAYACNYTN------ACNCAR GTNGCNGTNGAYACNGARYTNGAYCAYGAYTAYAGYACNAARMGNCARMGNATGTCNYTN CCNGTNGGN---------------------AAYGAYAARCCNTCNACNAGYGGNACNATG AARAARATHACNCARAARGAYYTNCCNCARAAYGTNGTNAAYGAR------------TGY GAYAAYGTNCARTCNYTNGAYGARAGYYTNGAYAARCARACNATHMGNMGNATHAARAAY AAYCAYGCNTCNAARMGNTCNMGNGARCARMGNAARCARAARTTYGTNGARATGGAYATG GARGCNGAYGARYTNGTNATHAARAAYAARGARYTNMGNGARAARATHGTNGARYTNGAR AARYTNGCNAARGARATGAARGCNGTNYTNGTNGCNAARATGGCNGGN------AARGGN AAYGGNACNACNCCNYTNAAYGCNYTNYTNCCNMGNTTYTTYAARAAYCAYGAYTGYYTN YTNTGYCCNGGNAAYYTNGAYATHGCNATGCCNGAYGAYTCNGGNCAYACNATHGTNGTN GAYTTYYTNGCNCCNCCNACNCARGAYGGNTTYTAYTCNGCNGCNGCNGAYTTYATGAAY GARTTYAARTCNGARAARATHMGNCCNCAYTGGGCNAARMGNCAYGAYAAYATHGAYGGN ATHGCNCARTAYATHMGNGAYGTNTAYGGNAARAAYYTNGARGARTTYAAYMGNCARAAR MGNYTNGCNGAYGTNGAYTCNTGYGAYATGTTYATGAAYAGYTAYYTNYTNACNATHTTY GGNMGNAGYATGGCNGAYAAYGCNGTNGAYTCNACNAARAAYGARGARGAYGGNACNGAY TCNACNGAYTCNAARGTNTCNTCNTCNTTYGGNGCNMGNCARTAYTCNGAYTCN------ ------ACNAAYTCNTCNGCNYTNGAYAGYAAYCARGARGTNAGY---AGYTCNGAYATH ACNGARTCNGGNTGYYTNTCNAAYCCNCCNAARGTNCCNGGNACNTCNATGAGYCCNTAY AAYAAYGCNTTYTAYGGNAAYACNCAYAAYGCNGGNATGTAYACNAAYCCNTTYGTNTCN MGNACNCCNYTNAARTCNGAYGTNGTNTCNACNGAYCARTCNAAYAGYGGNGAYTCNMGN GARGGNYTNATHGCNCCNAGYMGNYTNAAYGCNGCNGTNAAYMGNGAYAAY---AAYTCN GARGTNGARGGNAAYMGNTCNTTYCCNAARCARTCNGTNYTNGCNCCNCCNAARYTNACN GGNGCNGTNTTYGGNAGYGGNGGNGGNAGYCAYGAYGCNCCNAGYTCNACNTTYAAYTCN TTYAAYTCNTAY---ATHMGNCCNTCNGTNTTYTCNGGNTCNTTYGAYTCNGGNATHTGY MGNGGN---GCNCCNYTNYTNAARCCNGCNAARYTNCCNGAYCCNACNAARTCNGGNGAY AGYAARGCNGAYTCNGCNAAYGARGCNGAR------GTN---------GTNGCNAARTCN GTNGARACNCCNGTNGCNAGYGAYMGNYTNAGYGGNGCNGAYGGNACNTCNGGNGGNAGY GARGTNTCNTCNTCNTCNACNTCNTCNTCNATHCCNCCNCCNTGYCCNCCN--------- GAYGCNGARGGNGGNGTNGGNGGNGARGGNACNCCNTAYAAYCARGAYATHGTNCCNGAY ATHAAYAARAAYAAYMGNYTNAARGAYTCNTCNGGNGTNTCNAGYAGYTCNCARACNTTY GTNTTYGGNAGYAAYYTNTCNCARMGNGTNACNGGNATHYTNTCNTCNCCNGAY---GGN AAYGARGCNTCNGCNTCNCCNGCNTTYGTNTTYGGNGARTCNYTNAGYTCNMGNGTNGTN GTNGARACNAAYGGNTCNACNCARCCNCAYAARGAYGAYGARAGYGAYTCNGAYTCNGGN AAYAARYTNAAYCARACNYTNGARGARTCNGCNMGNGARTAYCARGCNAARCAYGAYAAY AARACNGARYTNGARGTNGTNGARACNATHACNGGNGARGARGARGARTCNAAYGTNYTN CARGCNAAYGCNAARYTNTTYTTYTTYGARACNAGYAAYGARTCNTGGATHGARMGNGGN MGNGGNACNATHMGNYTNAAYGAYATGTCNGCNMGNGAYAAYACNAAYTTYCARTCNMGN YTNGTNATGMGNACNCARGGNAGYYTNMGNGTNGTNYTNAAYACNAARATHTGGCCNGGN ATGTCNYTNGARMGNGCNTCNTCNAARTCNYTNMGNATHACNGCNATGGAYACNGAYGAR TCNATHAARATHTTYYTNATHACNACNACNYTNAARGAYTCNGARAAYYTNYTNMGNGCN ATHGAYTGGMGNATHCARCARYTNAARATHCARGARGARCCNYTNMGNCAYCAYTCNGAY GCNMGNACNGGNGAYAARMGNAARGCN---GAYGAYGAYTTYGARYTNCCNYTNAARAGY AARAARGTNAAYAGYTCNCCNGAYCARGGNATHTCNATHAGYAARAARGARGARTCNGAY AGYAGYGTNCARGAYCCNGARACNGARGCNTCNTGYGARAGYCAYTCNTCNTCNYTNACN ATHAARTCNGARTCNGAYTAYCARTGYATHCAYTGYGGNTGYGARACNGAYAARYTNTAY CARGAYTTYAARGCNGGNATHACNAARGTNACNAAYTGYCARMGNTGYGGNAAYATHGTN GAYAARTAYGTNGARTAYGAYTCNGCNATHATHYTNYTNGAYGTNYTNYTNYTNCARAAR TCNGCNTAYGCNCAYYTNYTNATHAAYGTNGARGTNAARTCNCAYTGGAARTCNGCNGTN TGYYTNTGGACNGTNGGNGCNTTYATHAARYTNATHCARCARMGNTCNGARCAYTCN--- ------AAYGAYTCNCCNGGNATHGCNAGYTAYTCNTAYGTNGGNGTNGARYTNTAYYTN AAYTAYATHGTNACNGCNGTNGARYTNATGAGYTTYYTNYTNTGYGTNYTNGTNGTNYTN GCNATHMGNAGYTTYGTNYTNACNMGNAGYYTNAARYTNYTNAAYACNTTYTTYATHACN AARGCNATHYTNYTNTCNAGYYTNGGNTCNYTNYTNGCNATGCCNGCNYTNYTNTGGGGN AARTCNTAYAGYCCNATGTTYGTNTGGYTNGGNCARGCNTTYGTNTAYATGTCNTCNATG CARGCNYTNMGNGTNGTNYTNACN---GGNCCNTAYAARACNYTNYTNGCNGCNATHGCN GTNGCNTCNGGNATHACNGTNCARGTNGTNYTNTCNGARGCNYTNAGYGTNTGGYTNCAY CCNTTYTAYATGYTNCAYGTNACNYTNAARGARGGNMGNGAYYTNGTNGTNMGNGAYAGY TGYGGNACNAGYGAYCCNTAYGTNAARTTYAARTAYGGNGGNAARCARGTNCAYAARAGY MGNACNATHYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATHAARCARMGNGCNGTNATH GARTTYGTNAAYGCNGARMGNTGYACNCCNATHAAYGTNCAYGARMGNYTNAARTGYGTN TAYGGNGAYCCNTGYGTNGGNATHNNNACNGTNCARMGNTGGGTNAARGGNYTNACNGGN ACNAAYGCNGTNTCNTCNAAYATHAAYGAYCARGGNMGNAGYGGNCAYATGGCNTCNTCN AAYGTNTCNMGNACNYTNGTNAARTCNGTNAARGGNMGNACNTTY---TCNGCNGCNACN GCNGCNMGNGCNGAYAARGCNCAYATHGAYAAYGCNCCNAARTGYTCNATHAARAARYTN AGYAAYGGNATGATGGTNGGNGCNATHAAYTCNAAYTCNCCNGTNGCNMGNYTNGCNGTN GTNGCNAAYGCNGGNTCNMGNTTYGARGAYGGNGAYAAYYTNGGNGTNTCNCAYTTYYTN MGNATGTCNTCNMGNYTNMGNACNGAYAAYATGACNAGYYTNGGNATGACNMGNACNGTN CARCARYTNGGNAGYGAYATHACNATHATGGGNACNMGNGARTAYATHTAYTTYAARAGY AGYGTNACNMGNAAYTGYGCNGAYAAYATHGCNCARGTNYTNAARGARYTNACNACNAAR CARAGYTAYAARGCNTGGGARGTNTCNGAYGTNCARGCNGAYAARAGYGGNATGYTNYTN GAYYTNGCNYTNTAYCARTCNMGNCCNCAYGTNMGNGCNGTNGAYYTNYTNCAYTCNGCN GCNTTYMGNAARACNYTNGGNAAYTCNYTNTAYGCNCCNGARCAYGTNATHGGNAARATH ACNCCNGARCARGTNYTNCARTAYGTNAARACNTAYTTYAGYACNGGNMGNATGGCNYTN GTNGGNATHGGNATHGAYCARGCNCARYTNGARGAYATHGGNTCNTCNTTYGARCCNTTY GCNTCNGCNGGNGTNCCNGTNGARAARGCNACNTAYTAYGGNGGNGGNGARATHMGNGAR AAYAGYGGNGGNGAYGTNAGYTAYGTNGCNYTNGGNTTYGGNGGNGCNAGYYTNACNAGY AARGAYYTNATGGCNTCNGARGTNYTNMGNCAYATHATGGGNACNGGNCCNCAYYTNAAR TAYAGYAGYGGNACNGCNGCNGCNTAYYTNGCNAARGCNGCNGCNGGNGCNACNGAYGCN CCNTTYCARGTNTCNTGYYTNAAYGCNACNTAYACNGAYAAYGGNYTNTTYGGNTTYACN GCNGTNTCNCAYGCNTCNCARATHGARAARGTNYTNCARGCNGCNGTNAARCARTTYAAY GGNYTNGCNTCNGCNAAYATHACNGAYCARGAYGTNGCNAARGGNAARAAYCARYTNAAR GCNGARATHTGYATGCARTTYGARAAYCCNGAYGTNYTNYTNAAYTGGYTNGGNGARCAR GCNYTNAAYAGYGARGARYTNGTNACNCCNGARGAYATHTAYAARATGGTNGAYAAYATH AAYACNAAYGARGTNAARAAYGTNGCNAARAGYATHYTNMGNTCNMGNCCNTCNATGGCN GCNGTNGGNAAYGTNGCNGAYGTNCCNTAYYTNGAYAARYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARAGYGCNCCNGCNACNCCNTCNGARACNGCN GARACNGGNGCNGCN---------GAYGGNTCNTCNGCNGARACNGGNGARGTNGCNGCN CCNAGYGARGARTCNGCNCCNTCNACNGTNMGNACNGARTTYAARTGGGARAAYGGNGGN GARACNGTNYTNGTNAGYGGNACNTTYAAYAGYTGGCARGARAAYATHGCNYTNTCNAAR GAYGGNGAYGTNTTYAARGGNTTYATGGAYYTNCCNGTNGGNGARTAYYTNTGYAARTTY ATHGTNGAYGARCARTGGGTNGTNAAYAARAAYYTNCCNATHAARTCNGGNGAYGAYGGN CARGARAAYAAYGTNATHYTNGTN---------AARTTYTGYCAYTAYTTYYTNTGYAGY YTNGTNTTYYTNYTNACNATHTCNACNATHGGNAAYTTYCARYTNTTYGTNTCNAARCAR ACNYTNAARTAYTGGGAYGARGAYTCNACNGTNATHGGNTGYTTYYTNTGGGAYTTYGCN YTNATHTGYYTNTTYATHGTNCARCAYTCNGTNATGGCNACNTCNTGGTTYAARAAYCAY YTNAAYTCNTGGTTYMGNATHTCNGTNTCNGARMGNYTNYTNTAYYTNATHYTNACNTGY ACNTGYYTNATGATHATGATHYTNAAYTGGCARAGYATHCCNGAYGTNTAYYTNTGGTAY ATHGAYATGCAYGAYMGNACNTTYYTNTGGACNTTYTTYYTNYTNTGYCAYTTYGTNGGN TGGYTNYTNATHGGNYTNGARGCNATGYTNATGGAYGTNGGNGAYYTNTTYGGNTTYACN CARGTNTAYAAYTAYCAYAAYGGNYTNACNCARCCNYTNYTNAARAARAARGCNACNAAR YTNMGNGARATHTAYTCNMGNATGMGNCAYCCNGGNGTNGTNGTNYTNACNGTNYTNYTN TGGYTNTAYCCNYTNATGACNYTNGAYMGNGTNYTNYTNGCNTCNGTNTTYACNTCNTAY ATGGTNTGGMGNCAYAGYYTNGARGAYTCNCAYTGYGARTAYGGNGARAARTAYTTYTAY ACNGARGTNTCNMGNAARACNACNMGNCARTCNGTNACNTAYGARCAYGTNACNCARYTN ACNATHGAYACNACNATHACNGAYYTNTCNYTNTCNTAYGAYGAYAGYCAYATGAAYACN ACNYTNYTNATHACNACNATHACNGGNAAYCARTGGCAYYTNYTNYTNGARACNMGNACN TCNGARACNAGYTTYTCNCCNGAYTCNGAYYTNAGYGAYYTNGGNTAYGAYCAYATHGAR GGNMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATGGARAGYGAYATGAARATGATHMGNYTNTAYCARCCNCCNCAYGAYTGYCCN GARGGNMGNTGYGARGAYAARYTNCCNACNTTYYTNTAYTGYGTNGCNATHCCNGTNATH TTYYTNGCNTTYTGYYTNGTNATHYTNTCNAGYATHATGTGYTGYTCNMGNAARTCNTGY AARTGYAARAARTAYTCNTCNYTNACNGCNGARACNAAYGAYATHCARATGGARAGYTAY AAYACNATHMGNMGNGCNACNGCNAGYYTNMGNCAYATGTCNCARAAYMGNGARACNCCN GCNATGGGNAGYMGNGCNGGNTCNTCNGCNACNYTNGAYMGNTCNTAYMGNMGNACNMGN MGNGGNMGNGARTCNTGYCAYTCNGCNCCNGGNACNYTNCARMGNCARTAYMGN------ ---------------------------------------------AAYMGNTAYTCNGGN YTNGCNGARCARCCNCCNCCNCCNGCNTAYAGYATGCAYTCNGAYGAYGTNTTYTTYGGN TCNCARTAYYTNGGNGGNGAY---ATGCARACNAGYGTNCARTCNGAYTAYAAYCCNGAR MGNAAYGGNAAYGGNGCNCARCCNYTNYTNAAYCARAAYCCNGARCAYTCNTCNATHMGN ATHYTNTCNGTNGCNGGNGCNTTYGAYGCNGTNAAYTCNCCNTCNAARCCNGCNAAYTTY ATHATHACNTCNACNMGNGAYTCNCCNYTNAARTCNCARACNTTYGTNYTNAAYACNGCN AAYGGNGTNYTNACNCCNGGNGAYAGYATHTCNACNGTNTCNCARMGNTCNGTNYTNGCN TCNCCNCARYTNTCNCCNTCNCARGCNTCNCCNGTNYTNYTNGGNCAYYTNCARACNGGN GTNGGNGTNCARCARCARGTNTTYCARACNGCNAAYGGNATHACNTCNACNCARTGYTCN GAYACNGGNACNGTNTCNACNAAYTAYGGNGAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TGGMGNACNAARTGYATGAARATGGARAARGTNATHAARACN YTNTCNAAYCAYTGYGTNMGNGTNGTNGARCAYCAYGARGAYYTNYTNATHAARTTYATG AARAAYCARGAYCARTAYGARAARYTNAARGCNAARTGYAARGARMGNGGNGARCARATH AARCARGCNMGNCARGTNYTNATHCCNGTNTCNAAYGARYTNAARYTNYTNMGNGARAAR TAYGARACNGCNGTNCARTGYCARGTNAARGCNGARTCNTTYGCNATHGARACNACNACN AARAAYAARAARYTNAAYMGNCARAGYCAYATGYTNATGGCNAAYYTNGGNTCNATGAAY ATHACNGAYATHGAYATHAAYGAYGAYATGAGYGARGARGARGARGARAARAARTAYATH GARAARYTNGGNCARCARATHGAYGARYTNGARAAYGARAARATHGCNYTNMGNATHCAR GTNAARGARYTNGCNGARAGYGTNGARGAYGARAARGARTCNAARGARTAYYTNATHMGN AARATHGAYATHATGAARGARGARYTNCARAARACNAARGCNACNATHAARCAYCARGAR GARYTNYTNGARAARGTNGCNGCNACNTCNGARAARGTNTAYAARGARTAYCARGAYATG GARCARACNTGYMGNAARGARTTYMGNGTNMGNAAYGARGCNGARMGNGTNGCNCARMGN YTNTTYACNGARMGNGAYCARGCNMGNMGNGARAGYGCNATGGCNYTNGGNAARGTNGCN GAYAAYMGNAARYTNATGGAYGCNATGYTNGARATHCARGARYTNAAYGCNAARTCNGCN GARATGAARGAYGAYTTYGCNMGNAARATHYTNGARYTNGARGARCARGTNATGGCNGCN AARGARGTNTAYAAYGCNGARAAYYTNGARGCNGARAAYGARGARYTNAAYGTNGARAAR AAYACNYTNCARGARAARYTNGAYCAYAGYGARGCNGARATGGCNCARYTNCAYACNAAR TAYGARGAYYTNYTNGCNACNTAYAARACNYTNGARATHAARTTYGARACNGCNATHCCN CCNCCNCCNCCNCCNCCNGCNCCNCCNCCNCCNCCNCCNTCNACNTCNAARGTNGGNGGN YTNYTNCARMGNATHGTNGGNMGNAARGGNCARMGNGARMGNGCNAARGARTGYYTNACN AARGGNGGNGTNGCNYTNAGYGARAAYCAYTCNAARGCNGTNGAYGARATGATGCARMGN ATHAARAGYGGNAGYATHGGNYTNMGNCCNGTNYTNCAYAGYMGNACNCAR--------- ---------AARGAYAAYCARCCNAGYGCNATGAAYGARYTNCARGGNYTNYTNACNAAR ATGAARAARTCNAARAGYGARGAYGARATHTCNGTNTTY---GARGARACNGGNGTNGAY GARGARTCNGARYTNGGNAARATGYTNAARAAR---MGNMGNCARYTNTAYCARGARAAR GTNGTNCCNGARGCNCARATHGAY------------------ACN--------------- ------MGNCCNGTNCCNATGCCNMGNAARATGTCNACNATHYTNGAYGAYGCNGARGAR ------------------------------------------------------------ ------------AARGARACNGGNATHGARTTYGGNTAYYTNATHATHGAYGAYTGYTAY AGYCCNGTNAARGCNTCNAARATHYTNATGAAYGTNYTNGGNAARGAYATHACNATHAAR GAYCCNGTNACNAARGARGARYTNAARCCNGARAAYGTNTGGGTNGTNATHGGNGCNYTN ACNAGYGAYAGYACNATGGCNATGYTNTCNCAYYTNAARAAYYTNCAYMGNCCNGTNATH TCNTAYGGNGCNACNACNCCNAGYYTNGAYAAYMGNGGNATHTAYCCNTAYTTYTCNMGN ACNGTNCCNAGYGAYAARYTNCARGCNCARGCNGTNGTNGARATHYTNAARAGYATHAAR GCNTCNCAYGTNGGNGCNYTNGTNATHGAYAAYATHTAYGGNYTNGARYTNTTYMGNYTN TTYAARGTNAARGCNGARAARGARGARATHTGYGTNGARGAYGCNTTYAARATHGAYGAY TAYACNGAYGARCARAARATHGARAAYAAYYTNTGGGARYTNMGNGGNAAYMGNGTNAAR GTNATHGTNYTNTTYGTNAGYTCNACNATHGTNAAYAARATHYTNTCNCCNACNATGAAR AAYAAYTTYYTNTTYGTNGCNAGYGAYGCNTGGGGNYTNAAYCARAARATHTTYGARTAY GAYTTYGGNGARMGNGCNMGNGGNTCNYTNATHYTNGTNCCNAGYYTNCCNAARATHGAY TTYGAYYTNMGNACNCAYYTNCAYAGYYTNAAYGCNTTYAGYGAYGAYGCNTCNTTYTGG YTNMGNGARTTYTGGCARAGYTAYTTYCAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNAAY CCNCARGCNATGTCNACNCCNAAYGCNACNACNATGTCNTCNGAYCCNATHTTYAAYATG ATHCARCAYAAYCCNGCNATHATHATGAARCCNGCNTCNCCNGCNCCNGGNMGNGCNGCN ATHTTYGCNTCNCARGCNTCNGGNATGCCNGCNTCNGCNMGNGTNCCNTCNCCNYTNATG TTYAGYCARCARCCNCCNYTNCAYYTNAAYGCNCCNTCNCCNATHCAYCCNTCNCARYTN TCNCCNGCNCCNYTNAAYMGNTCNCCNGTNYTNAARMGNGGNATGAGYCCNCARGARYTN GCNGTNCAYACNCARGCNGTNATGCARAGYGCNYTNATHAARAARCARYTNCARAAYCAR AGYGARMGNTAYATHAARAARCARCARGARMGNTCNAARTCNCCNAAYAAYCARATHAAR GTNGTNAARCCNCARCCNGCNGCNCARACNGTNYTNCCNCCNACNCCNCARCCNAARGGN TCNACNGTNAAYACNTTYACNCCNACNTCNGTNYTNGTNAARATGCAYTCNGAYAARGCN ATHGARAARGARAARCARGCNYTNGARATHGGNGAYAAYAARCCNGTNGARTAYATGCCN TCNATGGARGARYTNAGYGCNGTNMGNACNTTYCAYCARGGNGGNGGNCARGGNCCNGGN TGYACNCCNACNCCNCCNGAYGCNAGYGAYATHAGYTTYYTNGAYCCNATHAAYCCNAGY YTNATHGCNYTNACNAGYCARATHGAYAAYACNYTNMGNATHAAYATHYTNCCNGGNAGY YTNTCNCARCCNATGTCNGTNGARGARAARCARGCNATGGGNTCNYTNTCNGCNGCNGCN YTNTCNGCNACNATHCARCARGTNTCNTCNAARATGAAYGGNCCNATGATHCCNTCNTCN AGYGTNAAYGGNGGNGGNGGNGGNGGNGGNAAYGCNGGNATHCARMGNTGGTTYGGNTCN GAYATHYTNAARACNCARYTNCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNTTYYTNGARACNTCNACNTGYAAYTAYTCNCCNCAYAAYGTNCAYACNGCN CARATHYTNCCNGGNGTNACNYTNGTNYTNYTNTCNCARGCNCCNMGNCAYATHYTNGCN GAYCCNYTNTAYCARGTNATGAGYAAYATHCARGAYYTNATHTAYGGNMGNMGNACNAAR YTNYTNMGNCARMGNAGYYTNCAYGTNTAYGARATHATHAAYTCNYTNYTNGGNAARYTN CAYAAYAGYYTNMGNAARTTYAARGGNMGNGARMGNACNYTNATHTCNGAYATHCAYGGN MGNTGGGAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TGG TCNAAYGAYGAYAARTCNAAYGGNAARMGNCAYGAYATHTAYMGNTAYAAYACNGARGAR GAYTTYAAYTCNGARATHCARTAYGCNCARATHMGNGAYCARGGNAGYTTYCARGAYACN CARAGYTCNTTYGTNACNCCNCARAARMGNGGNAAYMGNCARTTY---MGNGCNGTNYTN CCNACNMGNTCNTCNCCNMGNACNAARYTNTTYAGYMGNACNCCNTCNTCNCCNACNAAR ACNYTNGGNCAYAAYMGNTCNACNTTYAARCAYCCNCARTCNYTNCAYGGNAGYTCNAGY AGYCARMGNAARMGNCCNGCNTCN------------------------------------ ------TCNGAYCAYTCNCARTCNATGYTNGAYAGY------------------------ TCNMGNAGYCARMGNAARTGYMGNGCNTCNTCNYTNACNCCNGARCARTCNTTYCAYAGY AGYTCNAGYAGYCARCARAARTTYTCNACNTCNCARAARTCNYTNCAYAGYAGYTCNAGY AGYGARMGNAARTGYAGYGAYTCNTCNYTNACNCCNGARCARTAYCARTCNATHAGYCAR MGNAARMGNCCNGCNTCNTCNTTYACNCCNGAYTCNGARTCNTGYCARCCNYTNAAYTCN YTNACNCCNGTNATHAARMGNGTNCCNTTYACNACNGTNYTNGAYCCNCCNGARGCNACN GTNMGNMGNTCNCCNMGNAARYTNTCNYTNTCNAARGAYCCNAARCCNATGGARTCNACN YTNAARACNATGGAYTCNACNTCNAGYGAYTCNGGNGTN--------------------- ------------------------------------------------AARATGAARMGN TCNGARMGNCAYATGATGMGNYTNAARAGYATHATHGCNMGNGTNYTNGCNGARAARGGN GTNGARAARGAYAAYCCNATHTAYCARGCNTGYTCNAARAAYYTNYTNAAYGTNAGYATH ATHYTNYTNAARGCNYTNCCNAAYTCNAARAAYYTNACNGAYGARATGAARTCNGTNGTN TAYAAYCARGTNCARCARATHATHAAYYTNGARAARMGNMGNTCNGGNATHGTNYTNGAR TCNTTYGCNTAYCCNACNATGAARGAYMGNATHCCNATHATHATHTCNAARATHGCNGAY TAYYTNAAYMGNAAYMGNGAYTCNYTNAAYCARAARTTYAAYGGNCCNAAYTCNGARGAR GARYTNAARACNATHATHGGNGCNATGTCNTGYYTNMGNCAYGARGTNATGACNAAYAAR CCNGCNGTNCCNYTNAARGAYTCNGGNTCNGAYGCNAARGCNTGGAAYYTNCARMGNCAR ATHGARTTYAAYGGNGGNGARTCNCCNAARTGGTTYCAYAGYCCNTGGYTNTGGATGGAR TGYTAYATGTAYMGNMGNATHCAYGARGCNACNYTNATGAGYTCNTGYTTYMGNTCNYTN GAYGTNTTYGARGARCARAARCARAARGCNTTYCAYGGNTCNTAYAARTCNATHTCNACN YTNACNGTNCAYYTNTAYGARACNAARAAYATHGGNGCNYTNTGGGGNAAYAARTGYGAY YTNTCNATHTCNYTNGGNYTNGARAAYAAYCARGCNGAYAAYCCNYTNGAYCARYTNCCN AAYYTNGCNCCNAAYATHYTNGTNGARGAYACNGAYGAYGTNYTNAARYTNYTNMGNCAR CAYYTNAGYGCN---------GGNGGNGCNAARGTNTCNATHGTNYTNGAYAAYGCNGGN TTYGARGTNATGACNGAYYTNTGYYTNGCNGARTTYYTNYTNTCNTCNGGNYTNGCNTCN TGYATHAAYTTYCAYGGNAARGCNYTNCCNTGGTTYGTNTCNGAYGTNACNGARMGNGAY GTNTCNTGGYTNYTNGAYCARATGGCNTCNATGAAYCAYATHGCNATHAGYCAYYTNTGY CARACNYTNMGNAARCAYYTNTAYGAYGGNTCNATGACNTTYGARTAYAAYCCNTTYTGG ACNATGGCNCAYCCNTTYAGYCARATGGARTCNGTNTGYYTNGARYTNTAYTCNAARYTN AGYCARAGYGAYYTNGTNATHTTYAARGGNGAYYTNAAYTAYMGNAARYTNGTNGGNGAY YTNAGYTGGGAYACNACNACNGARTTYTCNCARAGYYTNCARGGNTTYMGNCCNACNGCN GTNTGYTCNYTNMGNACNYTNAARGCNGAYGTNGTNGTNGGNYTNAARCCNGGNCARGCN GAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNTTYYTNTTYTCNYTNTTYTTYACNNNNMGNNNNNNNNNNNNNMGNNNN MGNAGYMGNAGYMGNGAYMGNMGNMGNTCNMGNAGYMGNGAYAARMGNTCN--------- ------MGNAGYMGNAGYMGNGARMGN------------------MGNMGNAARGARGAR MGNGARAARGGNMGNMGNMGNAGYMGNAGYAARAGYMGNGAYAARMGNMGNAGYMGNAGY MGNGAY------------AARAARMGNMGNAGYMGNTCNCCNMGNMGNMGNTAYAGYMGN AGYCCNYTNMGN---GARMGNYTNCCNGARYTNACNGTNGARGARMGNGAYATHMGNACN ATHTTYTGYATGCARYTNTCNGCNMGNATHMGNCCNMGNGAYYTNGARGARTTYTTYTCN TCNGTNGGNAARGTNMGNGAYGTNMGNYTNATHACNGAYAAYAARACNMGNMGNTCNAAR GGNATHGCNTAYGTNGARTTYGCNGAYCCNGARTCNGTNACNYTNGCNATGGGNYTNACN GGNCARAARYTNYTNGGNGTNCCNATHATGGTNCARCCNTCNCARGCNGARAARAAYMGN GCNCARCCNGCNACN---CARGCNCARACNCARAARCARGCNACNGARGGNCCNYTNMGN YTNTAYGTNGGNTCNYTNCAYTTYAAYATHAAYGARGAYATGYTNMGNGGNATHTTYGAR CCNTTYGGNAARATHGTNGAYATHAARATHATGMGNGAYCAYGAYACNCARMGNTCNYTN GGNTTYGGNTTYATHAGYTTYGCNAAYGCNGAYGAYGCNAARAARNNNYTNGAYCARYTN AAYGGNTTYGARYTNGCNGGNMGNCCNATGAARGTNGGNCAYGTNACNGARMGNTCNGGN GARGCNGGNCARGGNCCNCARAAY------GGNGTNGGNGGNCARYTNGAYACNGAYGAR ATGGAYMGNGCNGGNATHGAYYTNGGNGCNACNGGNMGNYTNCARYTNATGGCNAARYTN GCNGARGGNACNGGNTTYCARATHCCNCARTAYGCNGCNAGYGCNYTNAAYAAYATHACN CCNGCNCCNGCNCCNGGNGTNCCNGCNGCNGTNTCNCCNGCNGCNAAYAAYATHGCNYTN CCNCCNGTNATHCCNACNACNGTNGCNGCNCCNCCNCCNCCNCCNGCNGCNGCNGCNCCN CCNGTNGTNGCNAAYGCNCCNCCNATHGCNACNCARTGYTTYATGYTNTCNAAYATGTTY GAYCCNACNTCNGARCCNMGNYTNACNTGGGAYCARGARGTNMGNGAYGAYGTNATHGAY GARTGYAAYAARCAYGGNGGNGTNYTNCAYATHTAYGTNGAYAARAAYTCNCCNCARGGN AAYGTNTAYGTNAARTGYCCNAGYATHTCNGCNGCNGTNGCNTCNGTNAAYTCNYTNCAY GGNMGNTAYTTYGCNGGNMGNGTNATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARYTNCCNACNGAYCAYMGNATHGTNCARYTNATGGAYTTYGTNAAYCAYACNGARMGN TAYACNATHTCNTTYTGYTCNAARCAYAAYYTNCARCCNYTNAAYTTYTTYTGYGARCCN TGYATHMGNCCNGTNTGYMGNGAYTGYACNGTNYTNGAYCAYAARGARGTNGAYGGNCAY YTNGTNATGGAYATHGARGARGCNATGGCNAARTAYACNCCNGTNYTNGARACNGCNATG GCNGARATGGAYGCNGARGCNATHAGYYTNGARGARAARMGNGTNGCNYTNGARAAYGTN ACNCARACNATHGAYAARGTNAARATHGARYTNYTNGCNGAYACNMGNGCNTGYATGGCN MGNYTNMGNAAYYTNATHAAYGARMGNGARAARGCNYTNGARGCNAARATHCAYCARGAR GTNGARAARGARAARACNAARYTNAAYGARAARGGNGARGCNYTNATGACNMGNAGYAAR ATGYTNGARATHCARATHGGNMGNYTNAARCAYGCNAARGAYGARAGYAAYGTNGARGAY ATHTTYCAYATHCAYCARGARGTNAARGARTAYATGGCNATHCCNCCNYTNAARATHMGN GARGTNGAYGAYGGNATHATGACNTCNTTYACNATHAAYACNMGNGAYGARCCNYTNYTN GCNTCNMGNATHAAYAAYTTYGGNGAYGTNGGNAGYAARGTNGARACNGCNGCNTCNMGN ACNAARTCNACNYTNMGNGAYATHTTYTGGTAYYTNTTYYTNGAYAARTTYCARCAYAGY CARAAYTAYCARGCNAARYTNTTYAAYMGNATHTCNCAYAAYTAYGTNAARYTNATGATG ATGTCNGCNGAYCCNATHGCNAARGAYACNTTYTTYAARGAYTAYCCNAARYTNATHTCN CARGCNGTNTAYGCNTCNTTYTGYTTYTGYTTYCCNGAYTCNTAYMGNCARTTYGGNGAR AAYTTYAARGAYAAYYTNGTNTAYYTNGTNTAYGGNTGGATGGCNGGNATHCARCCNGCN CCNMGNACNTGGYTNACNTGGGAYATGACNAAYYTNGARCCNCARAAYYTNAARATGMGN GARGARATGATGCARAARAARAAYAAYAARAARATGACNTCNTTYATHGAYTTYGAYTAY YTNGAYTCNYTNATHTCNACNAAYGCNAGYCARTAYGCNTCNACNATGTCNYTNGCNCAR TCNACNTCNAARTCNTCNACNACNTCNAAYYTNGGNACNACN---MGNAARCCNMGNATG CAYGCNMGNATHAGYAAR---TCNCAYAARCCNYTNTTYMGNACNTCNTCNCCNAAYAAR GCNCAYTCNCCNAAYACNACNCARGAYTCNACNYTNATHGAYGTNGTNGCNGAYGCNCAR AAYAGYCCNMGNATHMGNGTNAARGAYACNAAR---MGNGGNAAYGAYYTNYTNACNCCN GCNMGNGAYYTNAARMGNCARAGYGAYGCNYTNACNCCNATHMGNGARATGACNAGYGAR GAYGARGARGARGAYTTYGGNAARAARTTYTCNCARGTNTCNATGAGYCARATHMGNGAR AGYMGNAAYAARAARGARTAYGTNATGGARTCNCAYCCNATGGGNMGNGGNTGYGARTTY GTNMGNACNGCNTTYAAYGTNGARGGNMGNAGYCCNYTNGTNGCNCAYTTYYTNAAYATG AARGGNYTNACNCARGAYTCNGGNCARAGYATHTGGATHCARMGNGTNGARGTNGAYGAY YTNCCNCCNYTNGAYGCNACNACNTAYAARGAYGTNATHAGYGARTCNTCNAARACNATH AARAARYTNGARYTNGGNTTYCARGARYTNTAYCARAARAAYTAYAARCAYAGYCARYTN TTYATGMGNCARCARCARAARATGYTNMGNGARCAYATGCAYAARCARTCNGCNYTNYTN GCNAAYAARGARGARGTNAARGTNYTNTGYGAYYTNATHATHYTNGARCARMGNAARAGY CARGAYTCNGTNTCNGCNGGNGCNGCNGCNGCNATHGARGCNGCNYTNATGGCNCARGAR GTNCCNGARGARGARMGNATHYTNCCNTCNGARTTYATHTCNCARGARGARAARMGNGTN CAYTCNGAYTTYTTYGAYGGNMGNCCNCCNAARACNCCNGARMGNTAYYTNAARATHMGN AGYTAYATHGTNGAYTGYTGGGTNAARAAYAARCCNATHTAYYTNAAYAARACNTGYGTN MGNCCNGGNYTNAARAAYTGYGGNGAYGTNAAYTGYATHGGNMGNATHCAYGCNTAYYTN GARTGYGTNGGNGCNATHAAYTTYGGNTGYGARCARGCNGCNTAYMGNAAYCCNCARMGN GGNATHAAYGGNGGNCCNAAYAGYMGNGCNAARGGNATHAAYAARGARYTNATGGCNGCN TTYCCNGCNTCNAARTCNGARTTYGTNMGNCCNMGNAARMGNMGNATHMGNGAYGARACN GGNGTNTGGGTNGAYGARAARGARYTNGARGGNAARACNATHGARCAYAGYATHGCNGAY AARAARAARMGNAARATHMGNAAYCCNAARCARATGAARCARATHTAYAAYCCNTTYAAR YTNGTNCCNTGYYTNTCNTTYACNAAYGARAAYCARGARCCNTAYAARATGGARATHTTY AAYACNGCNYTNTCNATHATGGAYATHCAYTCNCAYATHTCNAARACNGARGTNATHGGN ATGYTNGGNGGNCARTTYAAYGCNGAYACNAARTGYYTNACNATHAGYATGGCNGTNCCN TGYAARAGYATGAGYACNGGNATGCARTGYGARATGGAYCCNGTNTCNCARACNYTNGCN AGYGARCARATHGARGAYGTNGGNATGTCNGTNGTNGGNTGGTAYCAYTCNCAYCCNACN TTYAGYCCNGAYCCNTCNGTNMGNGAYATHGARACNCARCARAARTTYCARTAYTGGTTY TCNAARGGNGGNAAYCAYTTYGTNGGNGTNATHATHAGYCCNTAYAAYACNTCNGGNAAY TCNACNTTYTCNGAYATHMGNTGYYTNACNATHAGYGAYGARCAYAGYCARGARTTYYTN TGYAAYATHCCNTAYAARTTYGARTAYCARATHGTNTAYAARGAYAAYYTNMGNGARATH YTNGGNCCNGCNAGYGARYTNGCNGAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN TCNGARCCNTGGGCNAARCCNATHAAYCAYYTNTGGCARTTYTCNACNTAYGAYGGNGAR GCNGTNAARMGNTTYAAYCAYMGNATGTCNYTNMGNAGYCCNCAYTGYTCNGTNTGYTCN YTNTTYAARCCNTTYGARCCNGAYACNGARTGGTCNGTNYTN------GAYGCNATHGAR AAYAAYGGNGCNACNATHCCNACNMGNTCNYTNCCNATGATHCCNGARTCNTCNTTYGCN GTNAGYGCNGCNAAYMGNACNCCNTTYTGYGAYTAYTCNCCNGTNGAYGARGAYGGNYTN AGYTCNYTNYTNGTNTGYTCNTCNTGYAAYACNTGYGTNCAYGCNAGYTGYTAYGGNGAR TTYMGNMGNATHAGYCCNGARGAYTGGMGNTGYGAYGCNTGYATHTCNMGNGARCAYTCN AGYGAYCAYGARTGYGTNYTNTGYTAYYTNMGNGGNGGNGCNYTNAARCARACNTCNGAR GGNCARTGGGCNCAYGTNGCNTGYGCNYTNGCNATHAGYGAYGTNTCNTTYAARAAYATH MGNTAYMGNGCNCCNATHGTNACNGARAARATHGAYAARGARMGNTAYAAYYTNAARTGY TCNYTNTGYGGNCCNATHTCNCARTAYGCNACNAAYAAYMGNCCNTGYATHCARTGYTCN CAYGGNMGNTGYACNACNTCNTTYCAYGTNTCNTGYGCNTTYYTNGCNGGNATHAARTTY GARATGAGYGAYTGGCCNGTNCCNATHTAYATHTCNTGYMGNAARCAYYTNGTNYTNMGN CARAARGTNGARTCNMGNMGNGAYATGCCNGAYYTNGARYTNTTYAGYCCNGTNYTNGCN AARCAYAARAAYAARMGNTTYTAYTGGGCNAARGTNGTNMGNGTNGAYMGNAARAARYTN TAYGARGTNGAYTTYGAYGAYGGNTCNTAYAGYGARGAYYTNYTNCCNGARGAYATHGAR AGYMGNGAYTGYYTNCARCAYGGNCCNCCNATGAARGGNGAYCAYGTNYTNATHAARTGG GARGAYGGNAGYYTNTAYGGNGCNACNTTYMGNAARGTNAAYAAYAARGAYYTNTAYACN GTNGARTTYGARGAYGGNTCNYTNATGCARGCNMGNMGNGAYGARYTNTGGGGNGARAAY GARGARATHCCNMGNCAYGTNMGNAAYMGNATGTCNCARGCNACNGAYCARMGNTTYGAY YTNTTYGAY---AARGARGCNCARGAYGGNMGNMGNAAYAARAARAARGTNGAYTAYYTN AARATGYTNGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGCNGAYCCNGARGTNCARMGNYTN YTNGAYCARCAYMGNTCNYTNATHTTYGAYGARYTNACNCARAARGTNAARTGYAGYYTN ACNAAYCAYGARATGCCNGCNAARGTNACNGCNATHGARAGYTAYGTNAARGGNAARAAR TAYAARMGNYTNGCNGAYYTNGAYGARYTNTCNTAYGAYGAYCAYAARTCNCAYATHGTN TCNAGYAGYAARAARGAR------AAYGARATGTTYTGYMGNYTNACNYTNCAYCAYYTN GARAARACNGCNAARGCNATHCARMGNCAYATHAAYGGNAARAARTAYAARAAYGCNYTN GTNMGNTGGGAYGARTGYAARMGNACNGGNNNNAARTTYATHGCNCAYATHMGNMGNAAR GCNAARMGNCCNGARCARTCNGARGAYGAYGCNACNAGYAAYGGNGARAGYGGNGAYGAY GAYTCNAAYAAYGAYGCNGARGAYAAYGAYGAYATGAGYGAYYTNTAYCCNGARGCNGAY TTYCAR---------------------------GAYGARGARAGYGAYGARGAYGARATH GARAGY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNYTNTCNGCNTTYMGNAAYYTNCAYMGNGCNMGNAAR GARGTNTTYGCNGGNGAYGARMGNGCNYTNAAYGARGTNMGNCAYCARATHAAYTCNGAR TTYMGNGARAARYTNAARGARACNGAYGCNTCNAARATHGAYGARAAYTTYATHYTNGCN AAYGAYGTNGCNTAYYTNYTNMGNTCNACNGTNGTNCARYTNAARCARAAR------GAY GARGARACNTAYGARYTNMGNGTNACNAARAAYACNCAYATGCCNAARAAYACNCCNTTY GAYCCNAGYAARGARATHCCNATGAARCCNMGNAARAARTCNAGYACNGGNTGYGCNGAY ACNACN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHATHAAYATHGARCCNGAYAAYATHYTNTGGAARMGNGAR MGNGGNYTNCAYCAYGCNGGNGCNYTNMGNGGNTAYATGAARGAYCCNMGNGAYACNGGN GTNCCNMGNGGNCCNGAYGCNAGYCCNYTNYTNTGYYTNGARTGYGAYGCNTCNGAYAGY CARTAYGAYTCNTCNAGYCCNAAYAGYYTNAAYTGGYTNATHTCNGCN---GAYYTNTCN CCNTGYGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGACNGAYAGY CAYMGNATGTTYYTNCARAGYTTYATGTCNMGNGGNGTNATGAARGCNAAYGARATHAAR GCNTGYTAYGTNCARTGYAARAAYMGNTTYTCNGAYCARTTYGAYGARGAR--------- ------AAYTTYACNGCNCARTTYCCNAARTTYGTNCARACNATHAAYYTNGCNATHTCN GCNTTYAAYYTNGARATHAARAARGGNATHCARGARCAYGAYGGNYTNAGYGTNTAYTGY YTNGTNAAYACNGTNGARAGYGTNATHTCNMGNYTNTCNTCNACNTAYTCNACNAAYGAR YTNGARYTNTTYAARAARYTNATHGARTAYATHGTNGARTCNGAYGAYGGNAARATHGGN TCNMGNATHGCNYTNAAYYTNACNGARAARYTNGARAARMGNATGGGNAARGARGARGCN CARAAYTTYTTYAAYAAYYTNGARAARGARAARTGGATHGTNAARAAYGARGAYGGNAAR ATHGCNYTNTCNGTNMGNACNYTNYTNGARYTNGAYCARTAYYTNCARGAYATGTAYCCN GCNYTNGTNAARAARTGYAAYATGTGYAAYAARGTNTGYATGCARGGNATHTCNTGYCCN AGYTGYGGNATHAARATHCAYTTYAARTGYTCNAARACNTTYTTYTCNMGNCARCCNGAY GAYAARAARTGYCCNGTNTCNAAYTGYMGNGCNTCNTGG--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNYTNGAYGCNYTNYTNACNACNCAY AARGARGARGTNCARAARGAYGARATHCAYCARAARATHAARAGYGARYTNTTYCAYTCN ATHGARCARGGNTTYCARTTYGAYTCNYTNAAYGGNGARTTYGCNGARTAYATHGARCAR YTNGARGTNGCNACNCCNACNYTNYTNACNGAYCAYYTNTCNATGACNGTNTTYACNCCN AAYAARTTYTGYTGYYTNTTYAARGARACNATHAAYCCNTTYTCNTGYGGNTTYTCNMGN TCNCAYTTYTCNAARATHGAYAARGTNYTNGCNACNTAYAARTTYGAYGAYYTNGCNCCN YTNYTNATGTCNAAYATHYTNCCNACNTGYTTYCAYCARGTNTCNAGYCCNCAYTGYGTN YTNGTNTGGYTNATHMGNATHYTNTCNATHCAYCCNTCNTCNATGGTNGTNAAYYTNTGY AGYCARAAYYTNATHAAYATHATHCARAAYACNAGYGCNMGN---ATGGARGAYAGYGAR TCNACNGARCARTTYTGGTGYCCNAARCCNATHGARATHATHMGNATHYTNYTNAAYATG GGNGTNAAYCCNGTNTAYYTNYTNGGNGAYCARTCNATHTAYTCNGAYGARGAYATHAAR GARCAYYTNTCNGTNGARAAYGAYGARAAYGAYTCNATGCCNACNMGNTCNTCNGGNCAR GTNCARYTNGARAAYTGYCARMGNYTNYTNGARGTNYTNACNAARTGYTTYCARACNMGN CCNGAYTTYACNCAYCARGARATHAGYYTNACNGTNTGYATHATHATHAARATHTCNYTN GAYTCNTCNTTYCARAGYYTNGARYTNCAYCAYACNTTYCARGCNYTNYTNTCNGCNATH YTNGARTGYTAYAARGARTCNGARTGGAARTCNGTNGTNCCNCAYATGTGYCAYCARYTN AGYACNGTNCCNCAYCAYCAYAGYTGYTCNGTNTAYATHACNAAYATGATGCCNYTNAGY ATHMGNGGNAAYTAYGTNCARACNMGNYTNAGYTTYYTNYTNYTNTGYTCNACNYTNGAR CCNATGMGNAGYGAYATHCCNYTNGAYTCNYTNCCNCCNTCNMGN---------ATHGCN CAYYTNGGNMGNACNCARGAYCAYTCNCARYTN---TCNCCNYTNTAYATHTGYYTNMGN CARYTNATHATHGARGAYGTNAAYAARATGAAYTCNGCNYTNACNYTNYTNGAYMGNGCN GTNGGNGAYGARACNAAYMGNACNGCNCARCCNAARGARGARYTNCARTTYYTNACNAAY CARGTNAARATGGCNATHAAYGAYATHMGNGAYAGYATHAAYACNTTYGAYYTNTCNMGN YTNAARGAYAARATGATGGTNATGACNGTNAARTGGATGATGATGTCNTCNCARAAYACN AARAGYGTNCARMGNAGYATHTTYTCNTGGYTNACNTCNACNCCNCAYACNACNGTNMGN GARGARAARYTNCARGAYAGYGCNTCNTCNATHGCNGAYGARGARATHAAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------AAYAAYCARATHYTNGAYTGGTCNTTYAARYTNGAYGGNYTNTTYACN AAYGCNGAYCARGARGTNGTNTAYAAYACNGTNACNTCNGAYGTNGTNTCNAGYTCNYTN GARGGNTAYAAYGGNACNYTNATGTGYTAYGGNCARACNGGNTCNGGNAARACNTTYACN ATGACNGGNGCNACNGARAGYTAYMGNCAYMGNGGNYTNATHCCNMGNGCNATHTCNCAR YTNTTYMGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATHTAYGCN CARATHGARCARYTNTAYGCNAAYYTNTGYTGYATHAAYTTYCCNTTYCARCARAARGTN CCNACNAARTGYGTNACNCARMGNAAYATHTAYTCNTCNCCNTCNTGYGAYYTNYTNATG GARAAYAARAARYTNCARGAYAARATHGCNATHYTNGARCAYAAYATHGARCARYTNAAR TAYCCNGGNGARAGYGTNGAYACNGCNGAYCCNGARAGYGARCARTCNCAYMGNCCNGTN CCNGTNYTNAAR---GAYGTNMGNCARATHGARGCNATGTTYGARTGGACNGTNTCNAAY TAYTTYCARAARYTNGARYTNGARAARYTNMGNAARYTNACNCAYACNGCNTCNGARCCN TTYTAYATHGARCCNTGYGGNTAYYTNGCNACNYTNGARACNTTYYTNAAYGGNAAYGGN ACNGGNTGYGARAAYTCNATGTCNGTNTTYYTNMGNATHATHAARGGNGARTAYGAYACN YTNYTNAAYTGGCCNGCNATGYTNTCNYTNACNTTYATHYTNGTNAAYCARGAYAAYAAR MGNACNGGNAGYYTNATHTAYGCNGAR------GAYAARATHTTYCARTTYAARAARCCN TCNGGNACNACNTAYGAYGARAGYGAYTCNTGGGGNYTNATHGARTTYGTNCCNCAYCAR ACNATHAAYAGYAARAGYTAYATHAARAAYGGNACNATHAARYTNMGNATHAARATHATG GAYTTYGAYTCNTCNGCNAARTTYATHTCNTCNYTNGCNAARTTYYTNCARTCNYTNTGY AAYGGNTAYGTNGARTTYGAYAAYGGNGTNGARGTNATHGGNCAYATHTAYYTNAAYGTN GAYACNGGNAARAARATHGAYTAYGTNYTNAAYGARAARGTNTGYAARACNGAYGARAAY AGYGTNACNTTYATHAGYAAYAGYTTYCAYGCNCARCCNGCNGARAARCCNAARCCNAAR CCNATHGARATHGARCARGARACN------------------------GAYAAYGARATH ATHYTNATGGARGAYTCNGAYAARAGYTAYGARCARTAYGGNGAYAAYGTNCARCAYAAY TCNAGYCCNCAYCCNAARCCNCCNMGNTCNCAYGGNGCNTCNAARMGNTCNTAYAGYCAR TCNTTYGCNTCNAAYMGNTCN---TCNAARGCNGTNAARTTYGAYTCNACNTCNTCNAAY CCNAAYGGNGCNCAYYTNCCNTCNCCNTCNACNAAYGAYAGYTCNTTYAAYGTNTCNGGN AAYATHACNGCNGCNTCNGARTCNGAYYTNTCNCAYYTNTCNCARGTNTTYCCNGARACN GTNGAYCCNTCNAAYGCNCAR---GAYATHAARCCNATHYTNGAYAARGAYYTNAAYGTN ATHAAYGTNAARCARGARTAYGAYCCNTCNGGNGAYGGNGGNACNTAYGAYGAYCARGGN GAYTCNCARGAYCARATGTAYGARTCNMGNAAR------TTYCCNATGTAYATHGTNGAY GCNTTYACNGGNAARGCNYTNAGYGGNAAYCCNGCNGCNATHTGYYTNGTNCCNTCNGAY ATHACNYTNTCNGAYGAYGARATGCARAARATHGGNGCNGARATGAAYYTNTCNGARACN GCNTAYYTNCARATHATHGAYGCNGAYACNGAYTTYACNTCNGGNAGYAAYTTYTCNYTN MGNTGGTTYACNCCNACNTCNGARGTNGAYYTNTGYGGNCAYGCNACNYTNGCNTCNGCN GCNGTNYTNATHGAYGCNGTNGGNAAYGARAGYAARGTNATHGAYTTYTGYACNMGNAGY GGNACNYTNTCNGTNAGYMGNCAYCCNGAYAARGARGGNTTYYTNGCNATGGAYTTYCCN AARAAYGARCCNATHCCNCARGAYACNGARAARYTNGARAARYTNYTNATHAGYTGYGTN GGNGAYYTNGAYYTNGTNCARGARGTNYTNYTNTCNCCNACNACNAAR---AARYTNGTN GTNMGNYTNAARGAYCAYGTNCAYMGNAARGARYTNGARMGNYTNAGYCCNAARGCNAGY GARYTNYTNGARGCNGARCCNTCNGGNATGGTNATGGGNGTNGGNGTNACNYTNAARGGN TGYCAYGCNAAYGGNTGYYTNGAYGAYAARGGNACNGCNTAYGAYTTYGTNTCNMGNTAY TTYGCNCCNTGGMGNGGNATHCCNGARGAYCCNGTNACNGGNTCNTGGCAYACNGTNGTN GGNTCNTAYTGGGCNAARGARYTNAAYAARACNCARYTNTTYGCNMGNCARTGYTCNTCN MGNGGNGGNGAYYTN---YTNGTNGARAARGAYACNMGNGTNACNYTNATGGGNCARGCN GTNATHAAYYTNAGYGGNACNTTY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TAYGTNTCNAGYYTNCAR CCNCCNYTNTCNTCNTAYAARAAYTAYYTNAARATHGAYGARGAYGTNCARGCNGTNTCN GCNAAYGAYATHATHGCNGTNAAYGARTGYYTNGGNGARGGNGGNTAYGCNCARGTNTAY AARATGTAYAARGAYTTYTTYGCNATGAARGTNCARAARCCNCCNTGYTAYTGGGARTTY TAYATHTCNTGYGARATHCARMGNMGNYTNACNGCNYTNAARACNTCNATGGAYGTNMGN CCNTCNATHATGTCNATHAAYTAYGGNTAYTTYAAYGAYACNYTNAGYATHYTNGTNATG AARYTNYTNGARCAYGGNTCNYTNYTNAAYYTNGTNAAYYTNTAYAARYTNGAYTCNAAR YTNYTNGTNCARGCNGARCCNTTYGTNTGYYTNGCNACNATHGARYTNYTNCAYYTNTTY GARCARYTNCAYAARTGYGAYATHATHCAYGGNGAYGTNAARCCNGAYAAYTTYYTNYTN ATGGARYTNCCNGTNGTNTCNGAYAGYAARTGYACNAAYCARGTNTTYGGNTCNCAYYTN MGNGTNTTYTGYYTNACNGAYTTYGGNCARACNATHGAYATGCAYATGTTYCCNAARGGN ACNACNTTYMGNACNAARACNAAYACNGARGGNTTYGARTGYATHGARATGMGNACNGAY MGNTCNTGGACNTAYCARGCNGAYYTNTTYGGNYTNGCNGGNACNATHCAYGTNYTNYTN TTYGGNTCNTAYATGAARGTNTTYGTNGARAARGAYGTNTGGAARATHACNGGNAAYTTY GTNMGNAARTGGAAYGTNCCNYTNTGGAARAARYTNTTYCAYCARYTNYTNAAYGTNCCN TCNTGYGAYAGYYTNCCNGAYYTNGCNTCNYTNMGNGCNGARTTYGARGARTAYTTYTGY TCNAGYYTNATHACNTCNTAYAAYGARTGGGCNGCNAARATHAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CARGCNYTNCAYATHGCNAGY CAYGARTGYYTNAARATGCARTTYCARAGYYTNMGNGARCARYTNCARGCNAARACNGGN MGNGAYCCNGTNGGNYTNCCNGCNGARCCNAAYTCNAGYGTNGAYTTYGARTCNCAYTCN GARAAYGCNAGYGARGAYCCNGTNYTNGARATHACNATHTCNTGYTCNAAYYTNCCNTGY GAYGGNTCNGAYGTNCCNCCNAAYCCNYTNGTNGTNGTNCAYACNATGYTNCCNCCNCAR CARCARATHTGGYTNCAYCAYAAYCAYACNGARATHGTNGARMGNAGYAGYAAYCCNCAR TTYYTNAARACNATHGGNTTYGGNGAYMGNTAYGGNATHGAYACNAGYACNMGNATHMGN YTNACNGTNCAYCAYGTNGTNGARMGNATGACNATGTCNCARATHGGNCARGCNATHTTY ACNYTNCARGAYGTNYTNYTNAAYCCNGARYTNACNYTNGARYTNAAYYTNAARTCNCAY GAYGGNAAYATHAARATHACNGCNTGGATHAAYGAYGARMGNGTNTCNYTNTCNCARYTN AARACNCARCARACNGGNTGYTAYAAYMGNMGNTCNAARAGYATGTCNYTNGGNAARCAY AGYCAYAARYTNCARGAYCAYTTYACNAARGTNATHAARMGNTCNTTYMGNTTYGCNACN AAYGAYGARAARTCNYTNCARGTNTCNGARTTYATGGGNGARAGYYTNTGGACNTAYGAR YTNCCNGTNCARYTNYTNAARYTNTGGGTNAARGARGARAARATGATGGTNAARATGYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYAAR AAYGARACNGCNAGYCARGCNGCNATHMGNGARATGAARGARGARACNGGNTAYGAYGTN ACNGTNGTNGAYGTNTCNCCNCCNACNTCNYTNGAYCCNGGNGTNGGNAAYACNACNYTN AARATHGTNAAYTGYGARGTNGAYACNAGYAAYYTNAGY---AARGARMGNCCNAARCCN ACNGGNGGNGAYGCNGAYGARTTYATHCARGTNYTNGTNCARCCNATHAAYACNYTNATG GARAARYTNAARGARTAYGCNGCNCARGGNGAYTGYATHGAYTCNMGNGTNTAYACNTGG ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CCNCCNAGYGAYATH GCNTTYAGYAARGCNGAYCCNGTNCARYTNAAYATGTTYYTNAARYTNGTNMGNTTYGCN TGYGARGGNAARGAYYTNCCNGAYAARACNYTNAGYATHYTNGCNCCNGTNTCNATHAAR CARGTNGARAARCCNGTNACNTGYYTNGTNATHTCNAARCCNTCNGARTAYCCNATGTCN ATGCCNAARTCNYTNGARAARYTNACNATHAAYGARTGYYTNYTNMGNMGNGTNAGYCCN CARATHGTNTCNYTNTCNGGNYTNAARGARYTNGAYYTNGGNTAYAAYCARYTNACNACN YTNCCNGAYTCNTTYGCNCARYTNACNAAYYTNMGNAGYYTNYTNYTNCCNTGYAAYAAR ATHACNACNTTYCCNAGYGTNYTNYTNACNGARMGNYTNCARACNACNYTNTGYATHYTN GAYYTNMGNCARAAYGARATHGAYMGNYTNCCNYTNGAYGTNGTNAARYTNAARTCNYTN YTNACNYTNAGYATHAGYGAYAAYCARYTNMGNTGYYTNCCNGARTCNYTNGGNATGATG GCNTCNYTNMGNAAYGTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ACNGAR GAYYTNGAYTTYGAYGAYYTNGAYAAYATHGAYMGNGTNYTNGARATGGCNYTNCARAAR AARMGNGARCARAARACNGARAGYAARCARGARGAYGAYAARATHACNAGYGARATHATH GARTCNAARCCNTCNTCNATHAARGCNAARACNGARGCNGARAGYGAYGARAGYGTNMGN CCNGTNTCNGARGCNTCNGGNATGAGYGARACNGAYATGAARATGYTNAARTAYACNGTN AARGAYTCNGCNGARYTNGCNYTNCAYAARYTNCARTTYYTNGAYATHTCNACNAARAAY YTNTCNAARYTNCARGTNYTNYTNGTNGARYTNCARACNMGNTAYAAYGAYTGGCARGCN GGNGGNYTNTCNACNTCNTAYTTYCAYAGYCARYTNCARTCNTCNGARGCNYTNYTNTCN CARTAYGARGARAGYGCNGTNCCNTCNGGNTGGYTNTGYCARTGGGAYMGNGCNAGYTGY MGNTAYTTYTAYMGNCAYAARCAYAGYGAYCAYACNCARTGGGARTAYCCNCARAARGCN AAYAAYAARACNGARGTNAARGAYMGNMGNAGYGGNAARAARMGNMGNAGYAARGAYACN GARGARMGNGAYGARAGYGTNACNAARTCNMGNGGNAGYAAYTCNAGYAGYCAYMGNAGY AARAARAAYCARGARAARGAYMGN------------------GGNAARMGNGAYMGNCAY AGY---AGYAGYCAYCAYCAYMGNAARAARAARMGNMGNMGNMGNGAYCAYAGYAGYAGY AGYAGYAGYAGYGARGAYGARAGYACNCARTCNTCNTCNMGNCAYMGNMGNAGYAARMGN AARAARMGNGGNMGNTCNGAYAARTCNCCNAGYYTNGARGTNYTNGAYGGNCCNGARCCN GTNCAYGTNATHGARGARAGYCCNCCNCCNTCNATHGCNGAYAGYYTNAAYMGNCCNATH GAYYTNGAYGARGARAARACNATGGAYGARGAYGARGTNGTNGARGARGARGGNMGNAAR MGNGTNATGGARCARGAYYTNYTNGAYGAYGGNAARAAYCARCCNGCNGCNACNGCNACN GTNAAYGCNGGNGARTTYTGYGAY------AARCAYYTNGGNGGNGGNGARTCNATHGAY GGNGARGARATGAARGARGARGAYGGNGARAARGARGARGARGARGARGARGARGGNGAR ---AAYAAYGCNGTNATHATHMGNCCNCCNCARATHACNGTNCCNCCNTAYGTNGCNGCN ATHAAYGARCCNCARATGTAYTCNGCNACNTCNYTNTAYCCNTCNTCNATGATHCCNGCN GCNCCNCCNGTNGGNCARGARAAYGARGGNGARGCNACNCARGTNTCNGARGARGCNGAY AARGCNGGNAARAARAARAARAARGARAARTCNGGNAARGARAARTCNYTNAGYGCNAAY TCNAGYATHATGATGAARAARAARMGNGTNTCNTCNATGGTNCARAARTGGCARCARGTN AARAARGARGTNGARAARGARAAYMGNGAYAARGARYTNMGNCARGCNGCNATHMGNGAR AARATHAAYCARYTNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TAY AGYMGNGGNGARATHMGNAGYGTNYTNTCNATGATHGAYGGNGGNAAYAARAGYAARAAR CARGGNAAYAAYATHACNGGNYTNTCNAARAAYATHTCNGCNTTYGGNATHGCNGGNTTY GTNMGNTTYATGGARGGNTAYTAYATGATHYTNATHACNAARMGNAARAARGCNGCNATG ATHGGNCAYCAYACNGTNTAYAARATHGARGAYACNTCNATGYTNTAYATHCCNAAYGAY ACNGTNMGNCAYACNCAYCCNGAYGARAGYMGNTAYATGAARATGTTYCARAAYGTNGAY YTNTCNAGYAAYTTYTAYTTYAGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARAARMGNMGNCARGAR ---------------GARGARMGNMGNAARMGNGAYCARGARYTNAARAARCARGARGAR AARMGNMGNAAR---------------GARGARGARAARYTNYTNTAYGARGARCARAAR AARCARGARGARGCNMGNMGNATHAARGARGARATGMGNMGNMGNCARGARATGGARGCN ATHGARGCNMGNMGNAARGARCARCARCARATGGARYTNCARCARATHCARGARGARGAR GARMGNATGAARYTNGARACNGTNGARAARGARAARCARCARCARGCNGCNAARAARCAR CARYTNGARYTNCARMGNCARCARGARTCNYTNMGNAARYTNCARCARGCNCARAARGAR CARYTNGCNAAYATHCARYTNCCNGCNTCNAGYAAYTGGGCNAARCAYGCNTCN---CAR GGNGGNGTNGGNCAYTCNAARTCNYTNACNGARATHCARGARGARGARGCNMGNMGNGAR MGNGARMGNCARAARGARCARCARGCNCARAARGARMGNATGCARGARCARGCNGCNATH YTNCARCARATHCARATGCARAARTCNTGGGCNTCNCARGCNTCNAARGGNGCNAAYMGN GGNYTNTCNYTNYTNGAYATHCARCARCARGARAARGARAAYGCNAARAARGCNGGNAAR GCNCARAAY---------CAYCARGCNAARCCNAGYYTNGGNAGYGGNAGYACNTGGACN GGN------------------------------------------TCNAAYACNGGNYTN TGGGGNACNAAYTCNACNTGGGARAAYCCNACNCCNGTNCCNACNGGNGGNGGNGTNCCN CARTCNATHAARCCNCARYTNGGNAARAAYGGNYTNGCNGCNTCNCARAAYCARAGYCAR CARCARTCN------AARAARAAYGAYAARACNAAYAARGCNGCNGCNCCNACNAARCAR AARGARGTNGARACNGTNCARAARYTNTTYCARAAYAARAARCARGAYGGNTTYTCNGCN TGGGTNACNGARAARYTNTCNCARTTYTCNTCNGAYATHGAYATHCCNACNTTYGTNTCN TTYATHGTNGARGTNGAYAGYCCNGAYGAYGTNATHGAYTAYGTNAARACNTAYYTNGGN GAYACNAARGARACNCARGAYTTYTCNMGNCARTTYYTNGARAARMGNAAYCARTAYAAR AAYCARATGMGNYTNCARAARCARYTNGARGARGAYAGYATHTGGGGNCCNGCNCCNGCN ATHAAYCCNCAYAARACNTCNTCNTCNGAYCCNYTNAARGCNGGN---GARGGNGGNCAR GGNAARTCNAARAAYAARAARAARAARAARGCNCARAARYTNGAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AGYCARMGN AARACNTGGAAYGCNCCNTCNGAYATHATHYTNTCNCCNMGNGGNCARYTNGAYACNGAR GCNATHATHAARCARGTNCARMGNGARAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GCNTAYGARGTNACNGAYGARGTNGARGCNGTNAGYGARCARYTNAAYGTNAAYAARTTY GAYCARGTNTGYGCNCAYYTNMGNYTNACNYTNGARAARGARGTNGAYCARYTNYTNGCN GAYATHGARTTYYTNCARGGNTGYYTNTAYGAYGARGCNAAYATHMGNGAYTCNGTNAAY ACNCCNCARTTYTCNMGNGARCCNACNYTNACNGARYTNMGNGARGARMGNACNYTNYTN GARAARGARYTNYTNTTYACNGAYAAYYTNAARTAYACNCCNCARGTNGAYMGNCCN--- ------------------------------------------------------------ ---------------------------------------------GCNACNGGNATHTGY AAYAARGCNAAYGARGARTAYGTNGARGARAAYTAYCARAARGCNGTNGAYYTNTAYACN GARGCNYTNGCNYTNGARGAYACNMGNGAYGAYATHTAYTGYTTYMGNGCNCARGCNCAY YTNTCNYTNGGNAAYATHACNGGNGCNATHAAYGAYTGYGAYGARGCNATHMGNYTNAAY MGNAARAAYCARAARGCNTAYATHAARAARGGNTCNATHYTNYTNAARATGGAYGAYGTN YTNCAYGCNCARAAYGTNTTYAARGARGGNCARGARCAYTGY---GGNGAYAARACNTTY GARGAYTGGYTNGGNAARGTNGARAGYMGNATG---------------------AARGAR YTNGARATHGGNCARCCNACNCARCARCARGCN------------CCNAAYYTNAARCAY AAYTGGTAYCARACNCAYACNCAYGTNATHGTNACNGTNYTNATHAARAAYGTNAARAAR GARGARYTNACNYTNGAYGTNGARGAYMGNYTNYTNAARATHGCNATHAARATGGGNGAY ACNTCN---AAYGAYYTNAARTTYATHYTNGCNCAYCCNATHGTNCCNGARCARACNCAR TCNAARYTNTTYTCNACNAARATHGARATHAARYTNAARAARTCNGARGGNATHCARTGG ATHAARYTNGARGGNACNYTNGAYGARGTNGARTCNAGYATHYTNCCNCCNTGYGCNGCN CCN---GCNGAYACNGAYYTNCCNMGNTAYCCNAGYTCNTCNCAYTAYACNMGNGAYTGG GAYAARYTNGCNGCNGARGTNACNGARGARGARAARAGYGARAARYTNGARGGNGAYGCN GCNYTNAAYCARTTYTTYCARAARATHTAYGCNGAYGCNTCNGAYGAYACNAARAARGCN ATGATGAARTCNTTYTCNGARTCNGGNGGNACNGTNYTNAGYACNAAYTGGTCNGARGTN GGNAGYAARAARGTNGAYGTNAARCCNCCNGAYGGNATGGARTAYAAR---------ATH ACNAARATGCCNAARMGNAARTCNGARGARGCN--------------------------- ---------GCNTCNGCNTCNCCNAARAARGCN------AARACNGARCCNAARAARGCN ACNACNGTNAARGGNMGNGGNMGNCCNCCNYTNTCNGCNGARGARAARGCNAARMGNGCN ACNTCNAARAARCCNTCN---GGNMGNGGNMGNGGNMGNCCNAARGGNTCNACNAARGCN TCNAARGCNAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CAYGGNGGNCCNAAYGGNCARMGNYTN AAYMGNMGNTAYYTNCAYTCNAARATHTCNYTNYTNGCNAAYTAYMGNGAYAAYTCNAGY GAYGGNYTNGCNTGYTGYGCNTTYGAYTGYGCNGGNGAYACNATHTTYACNGGNACNTTY GCNGGNGARYTNMGNGCNATGCCNATHGCNTCNTCNAAYGAYGAYTTYGTNGGNACNGTN TGYCAYTCNTCNCCNGTNATHCAYATHAGYACNTCNATGGTNGAYCCNAAYYTNATHGTN ACNGGNACNTGGGGNGCNTCNCARAAYTGYGCNYTNTGGGGNTTYAARMGNAGYACNGAY ACNTGYGTNYTNAARTAYMGNTTYGAYGARTAYCAYGCNACNYTNGCNAAYYTNAGYCAY GAYMGNTTYATHGGNACNAARGAYACNGTNGCNACNATHTAYGAYACNGCNACNGGNACN AARYTNCARACNYTNTAYGAYGARAGYAARGCNAAYAAYTAYAARTTYAAYGARGCNTCN TTYAAYCCNACNGAYGAYYTNGTNYTNAAYGAYGGNAAYYTNTGGGAYGTNMGNTCNAAY AARATGATHTAYAARTTYGAYAARTTYAAYCARTAYACNAGYGGNTGYTTYCAYCCNAGY GGNYTNGARGTNGTNATHAAYTCNGARATHTGGGAYATHMGNACNTTYMGNYTNYTNCAY ACNGTNCCNGCNYTNGAYCARTGYCARATHYTNTTYAAYCAYGGNGGNGAYGTNATHTAY GCNATHMGNGTNGAYGAYGARYTNTCNGGNGAYGARTTYYTNMGNMGNGAYTAYGCNTCN ACNYTNMGNACNTTYGAYGCNYTNAAYTAYAGYGGNATHGGNACNTTYGAYYTNAARACN AAYAGYATHTTYGAYYTNGCNGTNGAYMGNAAYGAYCARYTNATHGGNGTNATHGARAAY ACNTCNCARCAYGAYTCNGAYCCNGARGARTCNATHTGYMGNGTNTAYGARYTNGGNAAR TTYMGNGTNCCNGARGAYCARGCNGAYGARGARGARGAYAAYCCNCARAAYGAYAAYGGN GAYTAYGAYGAYGAYGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------MGNTCNCCNTCNAARYTNCARCCNATHGCNCCNAARACNTCNCCN TGYCCNAARTCNGTNCCNTAYGTNCCNYTNCCNMGNATHAGYCCNAARMGNAARGARYTN AAYMGNCARGTNMGNCAYATHYTNCCNAARTCNTTYGTNTTYGARACNAARATHCCNTCN CCNACNAARACNACNGCNYTNAAYYTNAARAARAARGCNACNYTNYTNTAYCARAARAAY CCNGTNAARATHCCNCCNMGNCCNGTNAGYGCNTCNACN------GAYGAYGGNAAYACN MGNACNAARTCNTCNATGYTNACNMGNTCNCARMGNGGNMGNACNAARTCNAARAAYGGN GARGARAGYYTNCAYATHTCNGTNAARMGNATGAARAARACNGARGARGAYTAYGARAGY GCNAARGARACNGAR------------------------------------------AGY GARGCNAGYGARTTYGARGARTCNTGYYTNTCNCARGARGARGAYGARGAYMGNACNAAR YTNGAYGAYYTNATGGCNGCNAGYACNACNATHMGNTTYGGNTCNAARCARCAYGCNGTN GTNGAYGAYGAYGTNAARACNAARGCNGARAARAARAARGCNYTNTCNYTNTCNYTNYTN CARCCNGAYYTNGTNCARAAYGAYCCNAARAARGAYGAYMGNGAYACNGCNTTYGCNCAR YTNTAYTTYAAYCARGTNAARGARACNYTNTCNTCNGAYCCNGARMGNTTYTAYAARTTY YTNTCNYTNYTNAARGAYYTNAAYAARGAYCAYACNAAYCCNGTNGARYTNTAYYTNGAY ATGGTNGCNYTNYTNTCNGGNCAYCAYCARYTNGTNGARGAYTTYGCNGGNTTYYTNYTN TCNTTYCARGCNGTNGARTGYCARTGYTTYTCNACNAAYTTYCARTAYAGYCARATHMGN CARTTYYTNMGNCARGTNGARATHAAYTGYGGNTCNTCNACNAAY---ACNTAYMGNAAR GTNYTNAARGCNATGTCNACNTGGTCNAGYATGTGYCARGARGGNAARYTNGARGGNAGY YTNMGNGARAARATGYTNGGNATHYTNAARAAYGTNCCNGGNGTNYTNGAYAAYYTNATH AGYTAYTTYYTNGAYGGNACNGTNACNGAYTGYCAYTCNATGGAYTTYGARGAYGTNTGY YTNGAYGARGAR---GARATGMGNGARGGNAAYGAYGARTTYGARAAYATHATHYTNCCN CAYGARMGNGARGAYTAYAAYACNAARACNTGYACNTGYAARTGYCAY---TAYAAYTCN CARGAYGGNAARTTYCARMGNMGNATHAARCAYTGYGTNTCNTGYAGYYTNCARGTNTAY GARGGNMGNCCNGTNYTNAARATGTCNMGNAAYGARATHMGNCCNATGTGYGTNGTNTAY CCNTCNGARGARYTNGARGARAARGARAAYYTNACNGARGTNAARAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GAYGGNGGN GAYTGGCAYATGYTNCARGARCAYATHAGYGARTTYYTNAARGTNAARTCNTTYAARMGN AARTAYCCNGAYYTNTAYMGNMGNGTNTGYGAYAARGARGARAARGAYTTYYTNMGNGAR AARGGNGTNGTNTCNGARACNCARTCNGAYYTNGGNYTNACNGCNYTNMGNAGYGARGAR GTNTAYGAYYTNATGATGAARGAYTAYAAYGAYMGNTAYCARGARTAYYTNTCNGTNYTN CARGARAARCARAARMGNGTNATGMGNGARAARCAYAARGARTAYGGNGTNGCNAARYTN GAYAARTCNAARATGGARGCNTAYAGYAARAARGCNGCNMGNYTNGCNGCNGARTTYAAY GCNAGYYTNATGMGNGARAARMGNGARGARMGNCARGCNTAYTTYGAYYTNCARACNTAY ACNATHCAYCAYACNAARAAYMGNTAYMGNTCNYTNCCNCCNGARAARACNAARGTNGGN TCNTAYCCNGTNGCNYTNATHACNGGNCARTAYCARGARAARTTYMGNCARTAYCAYCCN GAYGARYTNTGYAAYTTYCCNYTNAARACNGCNYTNACNGAYCCNCCNCAYMGNGTNAAR TAYCCNAARCARATHCAYGGNYTNGARAARTGYMGNATHTGYAARCARMGNTCNTCNAAR GARGAYMGNYTNAARGAYMGNYTNATHMGNTGYGCNCARTGYYTNAARATHGGNCAYATG AGYTGYYTNGAYYTNACNGAYGAYYTNGTNGCNGTNATHAARACNTAYCCNTGGCARTGY ATGGARTGYAARACNTGYGTNCARTGYATGGAYCCNTAYGAYGARGAYAARATGATGTTY TGYGAYMGNTGYGAYMGNGGNTAYCAYACNTTYTGYATHGGNYTNAAYGCNYTNCCNACN GGNCAYTGGGARTGYMGNAGYTGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AGYATGGCNAARMGNGGNCCNCARMGNGARYTNAAYGAYMGNAAYTGGGAYGAYGAR GARGARCCNGARGARGCNGGNATHTTYAARAARGCNTCNACNGAYACNATGCARCAYMGN GTNATHAARAARGCNAARMGNMGNGGNGGNCARGARGARGGNGGNATGAARACNGCNTTY GGNGGNTTYGGNGGNYTNATHACNAARTCNYTNYTNACNCARGCNACNGAYAARACNACN GGNAGYYTNAARGCNCCNTCNYTNGGNGAYTCNGGNTTYTTYACNGGNGGNGCNACNTCN TCNGTNGAYAAYAAYATHGARTCNTCNAARAGYGARATGACN------AARGAYAAYTCN GCNTAYYTNCAYGCNYTNAARTCNYTNAAYGARAGYGTNYTNGCNTGGATHAARCARCAY GTNGAYAARAAYCCNTAYATHATHYTNACNCCNATHTTYAARGAYTAYGARAARTAYCAY GCNACNYTNGARGCNAARAARACNACNACNAAYGGNTCNAGYTCNGCNTTYTCNGGNTCN GGNAARCARAGYGARATGAARACNTTYTCNTCNATHACNCCNATHAARTCNYTNGAYGAR AARGAYYTNAARAARGAYGCNGGNAARGARGARGAYAAR------------GARGCNACN AARACNCCNYTNTTYGCNTTYGGN---TCNGTNTCNTCNTCNAAYGGNGAYGGNTTYAAR TTYTCNTCNGCNGCNGCNACNACNACNACNTCNGGNTTYACNTTYGGNAARACNACNACN TCNTCNATHTCNACNGGNTTYTCNTTYGCNAGYATHTCNTCNTCNGCNACNAARACNACN GCNGCNGARACNACNGGNTTYTCNTTYGGNGGNACNAARCCNACNYTNACNCCNTCNYTN ------------------GGNACNGGNTTYTCNTTYAARGGNYTNGCNGCNGCNAARGCN ACNGCNGAYAAYGCNCARGCNGGN---GGNTCNCARGAY------GAYGAYGCNGARTAY GTNCCNCCNAARCCNGAYGTNAARGARATHAARGARGARGGNTCNYTNTTYTCNAARMGN TGYAARYTNTTYTAYCARAARGARGGNAAYTGGACNGARMGNGGNGTNGGNAAYGTNCAY GTNAARCCNYTNGARGGNTCNAARACNCARYTNYTNGTNMGNGCNGAYACNAAYYTNGGN AAYATHYTNYTNAAYATHAAYYTNACNTCNGGNYTNCCNACNTCNMGNCARGGNAARAAY AAYGTNYTNYTNGTNTGYGTNCCNAAYCCNCCNYTNAARGGNGAYGGNGARAARACN--- ------------CCNATHCCNATGYTNATHMGNGTNAARACNGCNGAYGARGCNGAYGAR YTNYTNGCNAARYTNGARGARMGNAARGCNYTNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GGN ATHATGGCNAARAARGCNATHAARGTNMGNACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GCNGARGGNGCNGTNYTNGARATH CCNGGNATHGAYAAYAGYTAYTGYCAYGARGCNATGYTNGAYTGYGCNAARTAYATHAAR MGNCARGTNGARACNYTNMGNYTNATHGARCAYGCNTTYACNYTNATHCARCCNGAYGCN GGNYTNGTNGTNACNGGNCAYAGYYTNGGNGCNGGNGTNGCNTCNATHYTNGCNGTNYTN YTNAARCCNTCNTAYCCNAAYYTNYTNTGYTTYGCNTTYTCNCCNCCNGGNGGNYTNATG AGYCCNTCNGCNAGYMGNTAYAGYCARGAYTTYATHTGYTCNATHGTNYTNGGNAARGAY YTNGTNCCNMGNYTNGGNATGTAYACNYTNYTNGAYYTNAARGTNAARATHYTNMGNTCN YTNTGYMGNTGYAAYAARCCNAARTAYCARATHYTNGCNTCNGGNTTYTTYMGNYTNYTN TGYTGYAAR------GCNTCNCARGAYGARTCNGARMGNGAYGCNAGYYTNGTNCCNMGN TAYGTNCARGAYCARMGNTGYGTNYTNGARGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATH CCNGGNAARAARGTNCARMGNAAYCCNTCNCCNTTYACNCCNATGCCNYTNTAYGAYGAY ATGAAYACNCCNGAYYTNAARAARGCNGTNCAYAARATHGGNGTNMGNCCNATGGGNAAR AARMGNATGAARCARYTNYTNAARCAYGTNTAYGARGARACNCAYCARTAYGARACNGAY TCNGAYAAYGCNGCNACNCCNGTNAAR---AGYCAYCAYCARYTNGCNCCNMGNMGNGAR CCNCARCARCARMGN---------------CARCARCARCARMGNMGNCARCARCARCAY CARCARCARATGAARACNTCNYTNACNGGNAAYMGNCARGAR------------------ ---------------------------GCNGGNAGYTCNAGYAGYGGN------------ ---------------------------------TCNGGNGAYAAYAAYGAYATHGGNAAR AGYAARAAYATGACNAARAGYAGYGGNGGNATHGGNAARCCN------------------ ACNGAYTGYGTNAAYGARGARGAYGAYGTNYTNGGNTCNCARGAYTCNAGYTTYAGYGAY GGNCCNGAYYTNCCNGARGARAGYATHYTNCARATHTGGCCNGAYGARGAYGAYATHGAR ATHCCNTGYACNCARYTNACNCARACNAGYATHGARGCNYTNAAYGAYMGNYTNATGAAY TTYYTNCARGAYCAYCCNCARACNTAYAARCARATHYTNATGTAYGARCCNYTNGARYTN GAYGTNYTNAARAARGCNATHTCNGARGCNGGNATHMGNATHGGNYTNGCNMGNYTNCAR GAYTTYYTNGAYGARMGNTGYATHACNTTYTCNATGAARAAYATGAGYAAYMGNAAYACN MGNCARGTNCARMGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNAAYYTNMGNGTNYTNAARGCNTGG TAYGGNYTNATHCARACNMGNTGGMGNGGNMGNGTNGARMGNAARTGYCARTCNCARGCN AARGARATHTGYYTNAAYYTNACNAGYGAYTAYGARAAYAARATHGGNATGYTNAAYAAR AAYATHGCNGCNYTNGARGARAARGTNTCNGTNYTNCARGCNGARMGNGARGTNTAYTCN GARCARGTNAARAARGCNTTYYTNMGNGGNATGTGYGCNYTNAAYATGGARACNATG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGAGYAAY GAYACNTGYTAYAARTGYGGNGGNMGNGGNCAYTTYGCNMGNGAYTGYMGNAAYGGNCCN MGNACNGGNGGNTTYATGGCNCCNAGYACNGGN------------------------GGN TTYTCNGGNCARAARTGYTAYAARTGYAAYMGNGTNGGNCAYTTYGCNMGNGARTGYCAR CARGAYCARGARMGNTGYTAYAARTGYAAYGGNYTNGGNCAYATHGCNAARGAYTGYGAR AARCARATH---ACNACNGGNGCNTGYTAYAAYTGYGGNAGYAGYGAYCAYYTNCARMGN GAYTGYCCNGARGCNATHGTNAARAGYTGYTAYMGNTGYGGNCARTCNGGNCAYYTNGCN AARGARTGYGCNGCNGAYATHCCN------------AAYAARCCNTTYGCNGAYGAYMGN AARTGYTAYACNTGYGGNGGNATHGGNCAYYTNGCNAARGAYTGYCCN------------ TCNCCNMGNAARGARTGYTAYMGNTGYAAYCARATGGGNCAYYTNCARAARGAYTGYCCN AAYGGN---TCNCCNAAYACNCAYTGYTAYAAYTGYAAYGARGTNGGNCAYATHGCNMGN GAYTGYAARGCNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TGGGTN AARCCNAAYYTNATGCCNTTYTTYTTYCARATGATHAARGAYTCNGARAAYTGYAARTCN ATHTTYGAYTCNTAYGGNATHMGNTAYTCNGAYACNTTYACNGGNYTNTCNACNATGGGN TCNGAYATGACNYTNACNMGNYTNCARTCNAAYATHYTNGARGCNTTYCARCAYGCNGAR AARCAY---TGYGAYAARTCNAARTCNTAYGTNACNTGYGARYTNATGACNCAYCCNGGN TAYGCNACNGGNAARCAYGAYGGNGGNTTY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------MGNGAYGARGAYMGNGGNGARCCNATHCAYATGYTNAARACNGCN TCNAAYGAYGARTAYATHGGNAARATHMGNAARMGNYTNCARGARGAYGCNTCNGCNMGN GARGARMGNGARAARMGNMGNMGNAARGTNYTNGGNGAYCARATGAAYGCNCAYCARGCN CARGARGARGCNMGNMGNGARGARATGATGGTNAAYMGNYTNATGMGNCARTCNCARCAR GARMGNMGNATHGCNGTNCARYTNYTNCARGCNMGNCAYGARAARGARGTNATHMGNCAR AAYMGNATHYTNMGNGARAARCARTAYCARGARMGNMGNYTNAARAAYTTYGARGAYGCN YTNGAYYTNGARGCNGARYTNGCNGCNYTNCAYAARATHGARTAYGCNGTNCARATHAAR CARGAYCARGARYTNCAYGAYCARATHGCNGCNCARAARGCNGARCARMGNTAYAARAAY CAYTAYGAYATGTGYGCNGARATGGTNGGNAGYATHGTNGAYTTYTCNTGYAARATHGCN GARTAYMGNGARYTNACNACNAAYYTNYTNCCNCCNAARYTNATGMGNGARTGGAARYTN YTNTTYACNAGYGGNCARCCNYTNTTYGARGCNGARGAYGTNGTNAGYACNGARYTNACN CCNGARCARGTNYTNGARGARGAYMGNCARCARYTNYTNGAYGARGGNGAYTTYATGGAR TAYAARGGNATGGCNGGNGARTGGAAYCCNCCNGARGAYGGNGARATHGCNGGNCCNCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TTYGGN TGYAARCARGGNGARMGNMGNCAYGARCCNACNAGYACNGGNCARMGNACNMGNCARMGN TCNYTNAARGTNGGNTGYCCNGCNAARYTNMGNGTNMGNGTNAARGAYAARAGYNNNCAR CCNTTYYTNAARYTNACNGTNTGYAAYYTNGARCAYAGYGGNCAYCARGTNAAYAARAAR ATHTGYCARYTNTAYCCNGARAAYMGNMGNGTNGAYYTNGAYGAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ MGNYTNMGNCCNTTYGCN---ATHGARTTYCAYMGNAARACNGGNAARYTNATHCAYACN ACNCCNAARAARTGYGGNGARGCNYTNTAYMGNGARAARATG------TTYGARTAYAAR GARCCNACNTAYATHCAYCAYGCNGGNACNGCNTTYGGNGCNTTYATGTGGTAYTGGATH YTNTAYCAYTGYTAYTTYGARTTYGAYCAYYTNGTNGCNAGYAARAGYTGGGARTTYYTN YTNACNATGAARAGYGAY---------------GAR------GTNTTYYTNAAYAARYTN GGNGARATHCCNGTNYTNAAYGAYGGNTGGTTYGTNGCNGCNGAYTAYTAYTCNMGNGTN AARGAYTAYAAYGCNYTNATGMGNATGACNYTNTCNATGGCNGARTCNAGYGTNAARGTN GCNGGNCARYTNTCNACNCCNGTNYTNAAYMGNTAYCARCCNCARYTNGAYAAYATHAAY GAYTAYGCNTGYAARAARYTNGAYGARYTNGARGAYAARTAYCCNGCNATHAARCARCCN ACNGARCARTGGAARGARACNTGYACNGAYYTNGTNGARCCNGTNGTNGTNMGNGTNAAR CCNGTNATHTCNCARGTNCARGGNATHGTNAGYAGYAGYAARCARAARATHTCNGGNATH AARACNGCNAGYTCNAAYATGGTNGTNGARGTNAARAAYMGNGGNGTNGGNACNGTNAAY CAYGTNGTNAAYTCNACNTTYGARACNGTNCCNGGNMGNTTYATHACNMGNACNGTNGAY GGNGCNYTNAAYGTNGCNGAYAAYYTNGTNGAYAARTAYATGCCNGAR------------ ---------------GARGARAGYGAYTCNAARACNAAYGGNGARGAYTCNGAYAARGAR AGYAGYACNGGNGAYATHGARGARATGGARGARATGGAYCCNACNCCNAAYMGNGTNYTN ATHCAYGCNCARTCNGTNACNGARAARATHMGNACNMGNATGTAYMGNAARGCNATGAAR GAYYTNACNTAYGCNMGNGCNMGNACNGTNTCNGCNYTNAAYMGNATGACNAARACNGTN GARYTNATHGAYTAYGCNAARAARAAYYTNAAYACNGCNAARGAYAARGTNGAYCAYATG TGGACNGAYATHGTNAARGAY---------------GAYCCNGCNGAYGARMGNACNGTN TTYGCNGGNACNATHGARGAYMGNATHGTNGCNYTNGGNMGNYTNGTNGCNMGNCARGTN AARTCNGGNGTNACNTCNTTYGARAARGCNTAYTCNGARTTYGGNGARTTYGGNAARCAY CCNATHTCNAARTCNMGNGARTAYAARGARTTYATHGCNACNTTYYTNACNATHGARTCN ATHCARAAYATHTCNTCNCARAGYYTNGARAARGCNAARGAYTCNYTNAARTTYATGCAR GAYAAYTTYCARAGYGTNATHAGYGTNACNCCNACNYTNAARTGGATGGCNGTNGAYATH AAYATGGARGAYATHCCNYTNAAYGARTCNGAYYTNAAYAAYMGNTGYGGNYTNTCNGTN MGNCARGCNTTYYTNYTNAARCARAAYTGGAARGGNGTNATGMGNAAY---GARGAYTTY GGNGTNGAYTTYCAYYTNMGNYTNTTYAARACNAAYGARGGNYTNCARTCNATGTTYCAR GAYTTYAARCAYATHCARTCNGAYGAYGAYYTNMGNTCNAAYGARGCNYTNGARTAYCAY GCNACNATGGTNATGAAYACNYTNGAYGAYGCNATHACNCAYATHGAYAAYTTYGARTTY GTNAAYACNYTNYTNTGYCARACNGGNGCNTCNCAYAARMGNTTYTCNGGNTTYGARCCN AGYACNTTYYTNAAYATHAARCARCCNTTYYTNGAYGCNGTNAARGTNACNYTNGGNGAY MGNTAYACNGARAAYATGGARAAYATHTAYACNATHGCNATHAAYTTYYTNGTNGAYACN ATGGTNGARGGNATGCARGCNTCNYTNGGNATGMGNTAYCAYATGGARMGNACNCARGAR ACNTAYMGNYTNTCNGAYCARYTNATHMGNGCNATHGGNAAR---GGNAARYTNCAYGAY YTNGAYGAYATHAAYGCNYTNATHGAYCARGGNGCNGAYATHAAYMGNMGNCAYGGNACN YTNYTNCCNYTNCARTAYGCNTGYTGYYTNGGNGAYTGGCARATHYTNCARATHYTNATH CARMGNGGNGCNAARGTNAAYGARCCNGAYGGNTAYAAYMGNACNGCNYTNCAYTAYGCN GCNGARCARGAYGARATHTGYGTNNNNYTNYTNYTNGARAAYGGNGCNYTNGCNGAYAAY GGNGAYGGNAAYGGNGAYACNGCNYTNCAYTGGGCNGCNTAYAARAAYAAYACNYTNTGY GTNCARMGNYTNYTNCARCAYGGNGCNAAYGTNAAYGCNGTNGAYYTNAAYAAYGAYACN TGYNNNAGYTGGGCNGCNMGNAARGGNAAYYTNGAYGTNGTNMGNGTNYTNYTNGAYTAY AAYGCNGAYGTNAAYATHMGNAAYATHCAYGGNCARACNGCNYTNAARAARTCNGCNGCN GTNCARGCNAGYGGNYTNAAYAAYGAYGARGAYGAYGCNTGYYTNGARYTNYTNATHCAR GCNTCNGGNCARTTYGAYYTNACNAAYATHAARGGNGARYTNYTNCCNYTNATGGCNMGN GAYAAYMGNYTNAAYGARGTNYTNMGNCCNYTNGTNAGYATGCCNMGNTCNYTNYTNGAR CARTGYMGNAARCARATHMGNCAYAGYATHGGNCARAARTAYYTNCCNGAYGTNGTNCCN GAYYTNCCNYTNCCNMGNAARYTNCARGAYTTYGTNYTNYTNAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TCN YTNYTNYTNGGNTTYCAYGTNYTNCAYGGNYTNYTNGCNGGNATHCAYACNAGYCCNCAY AAYMGNAAYACNMGNGCNTAYGARCCNAAYGCNTTYACNCARGTNMGNGTNGAYATHMGN AARYTNGTNCCNMGNAARAARAAYYTNAARYTNCAYMGNYTNATGMGNAARYTNGGNAAR GAYTTYGAYACNTTYTGGATGTCNCARMGNYTNCCNAAYGAYTTYTCNCAYATHYTNACN AARAARAAYGTNGAYGCNTCNYTNMGNTCNAARACNGCNTCNYTNGAYYTNTCNACNTTY GCNAARGARGTNTAYGCNGCNAAYMGNACNGGNAAYAAYGAYTCNAAYTCNGTNCARACN TCNAAYACNACNACNCCNAAYATHGAYGAYYTNYTNGAYTCNGARMGNTCNAAYATHGTN TAYAGYYTNGARTCNTGGYTNGTNCAYGTNGGNTCNTGYCCNGTNTAYTAYMGNTGGGAR GAYYTNGGNCCNYTNTAYTGGCCNMGNTGGGTNMGNMGNGGNTCNTGYTCNMGNMGNGAY ACNGGNAAYTAYGGNCCNYTNMGNCARTCNTTYMGNAARMGNAARAARAARCARYTNACN GARTCNTCNACNCCNTGYTCNTGGCCNCCNGGNATGCAYTGYATHCCNGCNAAYGARAAR AARATHAARGTNYTNMGNTGGACNTGYACNCAYTCNAARTTYTAYGARGCNTTYGCNAAR ---GCNTCNYTNGCNGTNGTNATGGTNYTNGTNCCNGGNGTNTCNGCNYTNAGYGAYMGN ATHCCNGTNATHGCNTCNAGYGCNGTNGCNYTNTTYATGYTNYTNATHYTNATHGTNGTN GTNGTNTTYGCNACNTGYTTYGCNCARTCNTGGATHAARTCNAGYATGMGNAGYAAYGGN AARGTNAARATGCCNAARTCNTAYTTYMGNAARAARCARGARATHMGNMGNMGNYTNYTN GCNGARTCNMGNTCNTCNGCNAARCCNCCNYTNGCNAAYGGNAAYGCNGCNCCNTCNGCN GTNCCNGTNGTNGAYAARGGNAAYACNGARACNATGGTNCARGGNTGGAAYCARGAYACN MGN---------MGNATHTAYGARGARAARGGNTAYACNATGGARYTNGGNGAYGARAAY GARGARGARTTYMGNATHGARACNACNATHGTNGAYAAYGARATHYTNGAYGTNGGNCCN TAYMGNAAYATG---GARTCNACNAGYGCNMGNCCNGTNGAYGGNAAYGTNTAYACNAAR CCNTAYYTNTAYACNAAYAAYGAYMGNGTNACNGTNACNAARAGYGCNAAY---MGNAGY AAYATGGCNAARYTNYTNGARAARGARGAYGCNYTNMGNYTNATHTCNAGYATHGAYAAY TTYYTNTTYGAYTGYGAYGGNGTNYTNTGGGAYGGNAGYGGNCCNATGGARAARAGYMGN GARACNATHYTNAARYTNAARGARYTNGGNAARMGNGTNTAYTAYGTNACNAAYAAYAGY TCNAARAGYMGNAARGAYTAYGTNGAYAARTGYMGNGARTGGGGNTTYCCNGCNGARGAR GAYGAYATHGTNTGYACNGCNTAYATGGCNGCNCARTTYYTNAARATGAARGGNTTYCAR GGNAARGTNTAYGTNATGGGNAARGARGARGGNYTNGGNAARGARYTNAARGAYGCNGGN ATHCCNTAYACNGGNCCNGGNCCNGAYCCNATHACNTCNACNGAYTCNACNGAYCAYATH AARACNGARYTNGAYCCNGARGTNAAYTGYGTNATHGTNGGNTTYGAYCCNCAYATHAGY TTYATGAARATHYTNAARGCNTCNAGYTAYYTNAARAAYCCNGAYTGYYTNTTYATHGGN ACNAAYGARGAYCCNTGYYTNCCNGTNAAYAGYAARATHMGNYTNCCNGGNGCNGGNAGY ATHGTNGCNCCNGTNAARGTNGCNAGYCARMGNGCNCCNATHATHGTNGGNAARCCNGAR YTNGGNATGTTYGAYGTNYTNMGNGAYYTNCAYCARYTNGAYCCNTCNMGNAGYATGATG ACNGGNGAYMGNYTNGARACNGAYATHGTNTTYGCNCARAARAGYGGNATGAARTCNTTY YTNGTNYTNTCNGGNCARAGYACNCAYGARGARATGATGGCNAARGARGCNGGNATHACN CCNGAYTTYTAYGCNGAYTGYYTNGGNGTNYTN------ATGAAYMGNAAYMGNCCNMGN AAYMGNAGYMGNGGNGGNMGNGGNAAYTTYATHATGGGNGGNGAYGGNYTNYTNGGNGAR GGNCCNCCNGCNGGNGGNCCNGGNCCNATGATGGGNGGNAAYCCNATHGGNYTNMGNGAY ACNCARYTNGCNYTNGCNCARTCNYTNYTNCARCARCARCARYTN---ATGAAYTCNGGN TTYGGNGGNACNGGNGGNGAYTTYGGNTCNYTNGGNGCNYTNGCNGGNGGN--------- ATGCAYTTYYTNCARCARCAR------CARATGMGNCCNCCNATGGGNGGNGGNGGNATG GGNGGNGGNATGGGNGGNATGMGNAAYGAYMGNAARMGNAGYGGNGGNCARYTNMGNMGN GAYAAYGAYGARAARMGNGGNMGNMGNGAYTCNTGGGGNMGNGGNGARMGNGAYMGNTCN ---CAYGGNAAYAGYAGYMGNAGYGGNCARGAYMGNGAYMGNAAYMGNTCNAGYMGNMGN GAYTCNGAYAARGAYAARAARAARCARGGNGARGAYTAYGAYCCNGCNGARCCNACNGAR GAYGAYGAR------GAYGGNAARAARAAYGAYGGNTCNAAYYTNTAYTGYCAYGTNTGY GGNGTNTCNGTNTAYGAYGARGARAGYTTYCARMGNCAYYTNAAYGGNYTNAARCAYAAR GCNMGNATGGARAGYATHGCNTCNGTNCAYACNATGMGNTCNTCNCARYTNAAYTCNMGN YTNAARGCNGARGARCAYYTNMGNAAYATHGARMGNAARGGNGGNMGNGAYCCNGAYTAY TTYTGYAARATHTGYAAYAAYGAYYTNGCNATHCCNTGGGARAARCAYMGNTAYTCNAAY ATHCAYAARCARMGNYTNYTNCARGTNMGNAARGGNTGYGGNTGGTGYAARGTNCAYGAY TTYACNAAYTTYACNGARGTNYTNGARCAYMGNGARACNGAYGARCAYAARAARAAYGCN GAYYTNTAYGGNAARAARGARGARGAYAAR---GAYGAYTCNMGNMGNMGNYTNAARGAY GGNAARGARMGNGARMGNAGYAARTCNTCN---------------GARAARGGNAAY--- ------GAYACNAARGAYGARGAYGARGARGARGAYYTNACNATHCCNGARTAYAAYGCN GARGTNCCNGTNGGNYTNGAYTAYGTNATHCCNGTNACNGGNTAYTTYTGYAARYTNTGY CAYAARTTYTAYAAYAARAARTCNGCNAARGCNACNCAYTGYCARAGYACNATGCAYTAY GARAARTTYAARGARGCNACNGARGTNAARATHGCNGCNMGNGARAARMGNYTNGARGAR GARMGNYTNMGNAARGARAARGARGCNGARGARGARGAYGGNGAYGARGGNMGNAARGAR GARCARGARGARACNAAYGAYGAYGAYGARGAYGCNAGYGGNGCNGARGAYGARGARGAY CAYGGNGGNGARAAYGARGARAARGARGCNATGGARGARGAYGARGAYGARCARGAYGAY ---------------ACNATHYTNGARGARGARGGNGCNGARGAYGTNGGNGARGARGAY GAYGAYGAYCARYTNGAYGAYGARCARGAYYTNTCNGGNAGYATHGGNGGNTCNGGNYTN ATHGAYGGNACNATGGARAGYTCNAGYTTYATGTAYATGGCNGGNGAYYTNGCNCARGCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CAYCCN AGYCCNCCNTCNCAYCCNTCNTCNCARCCNATHYTNYTNAARCCNTAYTAYYTNTCNGTN GTNGARAGYACNCARCARTCNCAYAAYGCNTCNGCNGAYGAYGGNCAYATHGCNAGYYTN ATHCARAAYTAYGARGARGTNGARGGNMGNMGNATHAARGARYTNGTNTCNAGYMGNAAY CARCAYAARAGYAARGGNAGYTCNGARATGTAYGARAARTCNGAYGTNAARCAYGGNGAY MGNATGTTYCAYAARTTYYTNAARGARYTNCARAARTTYCCNGGNCARTGYATHMGNTAY GAYMGNTGYGGNCARCCNYTNYTNGTNCARGGNYTNAAYCCNGTNGARTCNGTNATHCCN YTNTGYTCNAARTGYGGNGCNAGYMGNGTNTTYGARYTNCARYTNGTNCCNGGNYTNATH CCNTGGYTNTCNTCNCARGAYGAYACNCARTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGGCNCARTAYATHCARGTNGTNGARGAYGARAAYGAYGARACNATH GARATHCCNAGYGARYTNAAYGGNACNYTNYTNYTNACNACNYTNGCNGCNCARTTYCCN GGNGCNTGYGGNYTNAARTAYMGNAAYCCNGARACNMGNGCNTTYMGNGGNATHMGNYTN GTNGAYGGNATHYTNCAYCCNGARAAYGGNATHTGGGGNAAYCAYCARTAYGTNGCNGTN TTYCCNAARGARAAYAARMGNAARGGNGARGAYGGNTTYGAYAAYCCNGCNGCNAARACN AARMGNYTNGARAAYCARAARTGYTCNGAYYTNATHGTNYTNGGNYTNCCNTGGAARAGY ACNGARGAYGAYYTNAARAARCAYTTYTCNCARTTYGGNGAYYTNGTNYTNGTNCARGTN AARMGNGAYATGAARAGYGGNCARTCNAARGGNTTYGGNTTYATHMGNTTYTCNAAYTAY GAYGCNCARAAYAARTGYTGYGCNCARMGNCAYAAYATHGAYGGNMGNTGGTGYGAYGTN ACNATHCCNAAYTCNAARGTNAGYTCNTCNTAYGGNGGNGCNGAYTAYGAYTAYGAR--- ---------------------------------------------GAYMGNGAYGGNMGN TAYCARGARGGNAAYAAYCARATGATGAGYMGNAARGTNTTYATHGGNMGNGTNAGYGAR GAYYTNAAYGTNGARGAYYTNMGNGCNCAYTTYTCNAARTAYGGNGARGTNGTNGAYGTN TTYATHCCNAARCCNCAYMGNGCNTTYGCNTTYGTNACNTTYTCNGAYGCNGAYACNGCN CARTCNYTNTGYGGNGARGAYCAYATHATHAARGGNACNAGYGTNCAYGTNAGYAAYGCN GCNCCNAARACNTCNTAYGAYMGNGGNCARGARMGNGGNAGYAARTCNTAYGGNGGNCAY GGNCARGGNGGNGGNTAYATGCARCAYGCNGGNMGNGGNCCNGGNCCNATHGGNGGNAAR GCNAAYGGNGCNGAYGCNGGNYTNAAYAGYAGYAGYYTNGGNATHAAYYTNATHAAYCAY GCNATGATHGCNGCNGCNCARGCNATGYTNTCNAAYAGYAAYAGYTGGAGYGGN------ ---CAYAGYCARGGNGCNACNGGNGGNAGYATGGGNGGNGGNGAYCAYCCNACNTCNATG GGNCARGTNTCNAGYCARGGNGGNTTYGGNAGYATGGCNGGNGGNAGYGGNGGNGGNGGN GGNAGYGGNAGYTTYTGGCCNAAYGARGGNAAYTCNGCNTCNGGNGGNCAYTAYGGNGGN TGGGGNGGNTCNCAYGGNGGNMGNGGNGGNACNGGNTGG---------GCNGTNGGNYTN AGYYTNGAYAAYCCNGTNTTYMGNGCNTTYYTNGGNTAYTCNGCNGTNGTNYTNGGNAAR ACNGTNYTNATGAGYGCNATHACNGCNTAYCAYMGNGTNACNAARCARGTNTTYGTNACN GARGARGAYGTNACNATHTTY---------AARGCNAARAARGGNGTNGTNYTN---AAY GAYCCNGAYATHGARMGNGCNMGNMGNGCNCAYCARAAYGAYYTNGARAAYATHGTNCCN TTYATHYTNYTNGGNYTNYTNTAYGTNACNACNGGNCCNGCNYTNTCNACNGCNYTNYTN CAYTTYMGNATHTTYACNGCNGCNMGNYTNYTNCAYACNATHGTNTAYYTNGGNAARGTN CCNCARCCNGCNMGNGGNGTNACNTTYTTYATHGGNTTYTTYGTNAAYGTNTCNYTNGTN TGYCAYATHATHAARGARGCNGCNTTYGGNATHTTYCARCCNCAYATHCARCAYYTNYTN TGYYTNGCNACNTCNGTNGAYATHGTNYTNYTNGGNGTNAGYTTYTCNAARACNATGGAY GGNGAYGAYMGNGARATGCAYYTNYTNCCNGAYCCNYTNTTYTCNATHCCNACNGAYGGN ATHTAYTTYACNTCNATHGTNGGNTGYGAYAAYGGNMGNGTNTTYATGGCNYTNATHTAY CARGCNAARGAYGGNTGGTTYAGYGAYAARTGYTAYAARGTNAAYCAYTCNACNAGYTCN TTYTCNTTYYTNGTNCCNTCNTTYYTNAAYTTYTCNTTYGGNGARGAYGAYGCNYTNGTN CARATHTGYATHGAYGAYTCNMGNGGNATHYTNTTYGCNMGNACNCARAAYGGNTCNATH CARGTNTTYGAYYTNGGNGCNAAYAARAARGGNYTNAGYAARGTNGCNTAYCARTCNCAR GCNTCNATHYTNAAYACNGCNTCNGCNATHGCNMGNACNATHGARAARTCNAAYTTYAAR TCNATHATGCAYATHTCNGCNATHACNCARMGNGARGCNGAYAGYGTNCAYYTNGTNGCN ATHACNGARACNGGNGTNMGNYTNTAYTTYTCNACNGTNCCNTCNAARCARYTNGAYTAY MGNCCNTGYACNYTNAGYYTNATHCAYGTNMGNYTNCCNCCNGGNTTYTCNGCNACNTCN ACNCCNGARMGNCCNACNAGYGTNCAYACNGCNTTYTAYAARAARGAYACNYTNATGYTN GTNTCNTCNCARAGYCARGAYMGNGAYACNYTNTGGTGYATHAGYCCNGAYTCNTTYCCN TTYCARAARCARYTNATGGARGCNCAYACNATHATHTCNTCNGGNGGNAARACNTGGGCN ATHGARGARGTNCCNTCNAARGCNCCNCCNGCNMGNTCNYTNATHCARTCNTCNTCNACN MGNCCNGTNGAYCCNCCNTGYGTNGTNACNCARCAYGCNTTYCCNCCNMGNMGNTTYGTN GTNYTNAGYACNCAYGGNGTNCAYATHGTNCARAARYTNMGNCCNGTNGARCARYTNAAR GTNYTNYTNYTNGARTGYGGNGGNCCNGAYTCNGARCARGTNAARGCNTTYTTYMGNYTN CAYAARYTNGAYCARGCNTGYGCNATHTGYYTNGTNYTNGCNTGYTCNMGNGCNACNGCN GAYCARCARGTNTCNGAYTGGGCNMGNATGGCNTTYTTYATGTAYGGNGGNGARGCNCAY TGYAAYTTYTCNAGYATGMGNCCN------------GGNAGYCCNYTNCCNGGNTCNGTN ATGTAYAGYCCNGGNTCNATGATGYTNCCNAAYAGYCCNYTNCCNAAYATGATGACNTCN ACNCCNGCNCCNGGNGCNATGGCNGGNTCNCCNGCNGTNCCNGGNATHGGNGGNGGNCCN YTNCARGARGTNATHTAYTCNGGNAARCAYAAYGGNATHTAYATHTTYYTNAGYMGNATH YTNMGNCCNTTYTGGGAYAGYCCNGTNACNACNGARTTYYTNCAYGAYTCNAARCARGGN AARGTNTCNTTYYTNACNTCNAAYTTYAGYGTNGARGARYTNTGYACNGCNYTNGARATG GTNMGNGAYYTNTCNGAYTTYGTNGAYTTYAAYTCNAARTTYGAYYTNGAYTCNCAYATH GAYATHATGAAYACNGGNMGNGGNMGNYTNGAYGGNAGYATHGAYGARCARAGYMGNAAR MGNYTNCARATHGARGTNCARMGNATGGARAARATGTCNYTNCARCAYYTNCARGAYYTN YTNCAYMGNACNGARGARGTNYTNGGNYTNTGGMGNYTNYTNATHGAYCAYCARTTYCAY ATHYTNGCNGCNGCNATGGCNCCNGAYATHCARAAYCARYTNMGNAAYATGACNTTYAAR ATHYTNGTNACNAGYGGNAARGAYGTNTGYAGYACNYTNATHATHTGYYTNGTNAGYMGN TAYYTNAAYGAYAAYGCNACNATHGAYGCNATHAAYGAYMGNYTNMGNGARGTNTGYCCN ACNYTNTAYAGYACNGAYGAYGCNACNTGYTCNAARTCNAAYGARYTNYTNCARGCNGCN AARYTNAAYCCNAAYAARYTNGARAARGARYTNCARYTNCARGARGCNYTNCARYTNYTN AARGGNGTNTCNCARCCNYTNAAYYTNTCNGTNATHTGYTCNCARYTNGCNAGYGTNCAY TTYTAYYTNGGNATHGTNGARYTNGGNYTNAAYGARGCNGTNAARYTNGAYCCNCARGGN GTNGCNGTNCAYTTYTAYAAYAGYGGNGARCCNCARGARGAYATHCARGGNATGCARGCN TAYATHACNMGNATGGARTGYTAYAARTGYATHACNGAYACNYTNACNTAYYTNAGYGCN GCNAGYACNAGYCARGCNCARGTNCCNAAYATHCCNTTYATGGCNACNACNAAYCCNGTN GARCCNAAYMGN---ATGGARCCNCARCARGCNGARTAYTTYAARGARGARGTNTTYAAY ACNGCNYTNMGNTGYGAYGAYTCNYTNTTYCAYGCNGCNYTNTAYGARTGGYTNTTYGGN ACNAAYCARGCNGARAARYTNYTNGARATHAAYACNCCNTAYGTNGARCARTAYYTNMGN MGNAARGTNAAYYTNCARACNGAYAAYACNAGYGCNYTNGAYATGYTNTGGMGNTAYTAY GARAARGTNGARAAYTTYCCNGCNGCNACNMGNATHYTNTCNCARYTNGCNGARMGNCAY GGNACNAAYGTNAGYYTNACNCARMGNYTNGARTAYYTNTCNMGNGCNGTNGTNTGYGCN AARAGYTCNACNTCNMGNYTNGGNACNTCNGCNGGNGGNGARACNYTNCAYGARYTNGAR GARAARATGGARGTNGCNMGNYTNCARATGCARATHTAYMGNAGYYTNTGYAAYATGATG GGNYTNYTNCCNGTNAARAAYGCNAARGCNAARYTNGAYGCNGARYTNYTNGAYATHACN ACNYTNTAYGARGARTTYGCNGAYCCNTTYGARYTNCARGARATGAARYTNGCNATHGTN CAYTGYGCNGGNYTNTAYGAYGCNGCNYTNATHGARGAYYTNTGGMGNAAYATHATHGAY AARGARATHAGYAAYACNTCNCARATGTCNGGNYTNGAYMGNATHAAYACNATHGGNACN AARYTNTCNACNGTNGCNAARYTNTAYGTNAGYGCNGARMGNTAYTTYCCNGTNGCNYTN ATHYTNMGNCAYYTNGARCARAARTCNTGYGARYTNAAYYTNGAYYTNGARTGGGTNTTY AARATGATGYTNGAYGTNGGNGTNGCNCCNGCNMGNYTNYTNGARYTNTAYGAYMGNYTN TAYAARTCNAARGAYGTNATHTGGCARAAYYTNCAYMGNCCNYTNCAYGTNYTNATHGTN YTNCAYGCNTTYATHGAYCAYATGGCNAARAAYCCN---GTNYTNYTNAARACNGTNAGY CCNCCNATGCARGTNTGGTGYYTNGAYYTNGTNGCNTCNTAYYTNGTNGAYYTNGGNGCN YTNGGNGCNTCNACNMGNGAYGTNCCNCCNYTNATGACNGGNTTYAARGCNACNCARGCN MGNYTNGARMGNYTNTTYAAY---ATHYTNCAYGARTAYGARACNAAYCAYGGNAAYGCN GAYYTNYTNYTNTAYACNCCNACNACNCCNAGYCCNGARGAYGTNAAYTGYCAYGTNGAR ATHCCNGTNACNMGNMGNGTNGGNGGNAARTGYGTNAAYYTNGGNTCNTTYATHGGNTGY CARGCNGGNATHTAYYTNGCNTTYGAYTCNATGTGYAAYACNCARATGGGNATHCCNTCN GGNCARTCNGGNYTNGCNTCNCARGCNGAY---AAYMGNCCNMGNAGYMGNAAYCCNTTY CCNAAYMGNMGNATGAAYCCNTTYMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GCNTAYGGNCCNACNACNGTNACNGCNAAYMGN------CCNGCNAAY ACNTCNTTYAAYATGTGYCCNGAYGARAAYYTNATHATHTAYTGYGARGTNGCNGTNAGY GAYGTNGCNCCNATGGCNGAYGTNACNYTNMGNGGNYTNCCNGGNGGNGAYCCNAAYTAY AAYTCNACNCARTCNGGNAAYTAYMGNTAYACNTTYTCNTTYMGNCCNCAYACNGGNGGN AAYYTNCCNTTYACNTGYGTNGCNGARAAYGTNATHTTYMGNGARGTNGGNMGNGARAGY GARYTNTCNGTNYTNATHAAYATHCCNCCNGARGAYGCNCCNGTNATHAARYTNAAYGGN GARATHATHGCNAAYGAYTCNGTNAAYACN---------TTYMGNGTNGGNATGGAYATH AAYGTNAAYTGYAARGTNGAYGGNGGNTTYCCNAGYGTNAGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNAARGAYTTYCAYGTNCCNATHACNATHACNAARGGNMGNGCNAARGTNMGNGARYTN TTYATGAARAAYAARCAYGTNACNGAYATHMGNGTNATHGAYATGYTNGTNATHAARGGN CARATGGARYTNGTNGARACNGCNAAYATHTGGAARCARMGNCAYCAYGTNATGACNTAY TTYAARGAYACNGTNAAYCCNAARCCNACNGAYTTYYTNAGYAARTTYTAYGARGGNCAR GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGAAYTCN GGNGAYAAYATHTAYMGNMGNATGTCNGGNCARCCNYTNTAYAARGAYAGYCAYGTNGAR CARGARYTNGAYCAYMGNGTNAARMGNGTNTCNGAYAARTTYTCNGARACNGTNAAYATG GTNGCNAAYGARCCNTCNYTNGCNTTYTTYMGNATHCARGARCAYGTNMGNAARACNYTN CCNCARYTNGTNGAYACNAARCAYGARGTNGARGAYGTNCARTCNAARGTNCARGGNTCN TGYTTYGAYGCNGAYTAYGCNATHAAYGCNGTNAARGCNATGCARAGYAGYGCNATHCAY TTYCARAAYATHCARGAYYTNYTNAARAAYGCNATGTTYATGAARCARCARATHACNTAY GARGAYAAYAARMGNAARCARGGNMGNAGYAGYCCNATGGCNGGNGAYMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARGCNGTNGTNAARAAY YTNGTNGARGCNTAYGARACNTAYATHYTNCCNCAYTTYGARGARYTNCCNAARGARGAR ATHGARAARCARCARMGNGARCAYTAYGARTCNTGYYTNYTNMGNMGNGARATGTTYGGN AAYATHCAYMGNYTNCCNGAYCAYGARTAYGAYCARATHYTNGGNGARACNGGNATHGAY GCNGAYGGNMGNYTNAARAARYTNCARYTNTAYGCNGARGCNATGGAYAARATGATHAAR GAYATHGTNTCNTTYGCNATGGCNATHCCNGGNTTYYTNGARATHCCNCARGARYTNAAR ATHAAYYTNGTNAARTAYTCNMGNCARGARTTYTGYYTNYTNAAYYTNTTYAARTAYGTN AAYGCNGARYTNATGGTNTAYAARGGNGTNGARYTNCAYTGGCARTGYTCNYTNGARATG GARAAYTCNGARTAYMGNACNATHYTNGAYACNACNTTYTGYTTYYTNAARAARTTYCAR YTNYTNAAYYTNTCNCAYGARGARTGYGTNYTNYTNMGNGCNYTNGCNATHATGGCNCCN GAYMGNGTNAGYCCNGTNAAR---TCNCARATHGTNCCNGTNATHTAYGAYAARYTNGTN AAYGTNYTNATHTAYYTNYTNAGYAARMGNTTYGAYCARCCNATGCARTTYTTYGCNAAR ATHATGAGYYTNGCNACNGARTGYMGNAGYAARGARGARGAYYTNACNTCNATGTTYAAR MGNYTNAAYYTNATHMGNTAYATHCCNYTNAGYGAYAARCCNTTYYTNTAYYTNATGTAY TCNGGNATHTAYGCNGGNGGNATHCCNATGACNAAYTCNATGTTYGCNTGYYTNAARYTN GARGAYGARTTYGARGARGARAARAARTCNMGNMGNAARAAYCARAAYCARGAYGARAAY ACNAAYACNAARAARAARGARGARAARAARAARAARAGYGCNATHGARAGYAARCARYTN CARCARYTNGCNTTYGGNAARCCNGGNTCNGCNGGNAARAARAARTCNGGNAARAAYACN AAYTCNAAYAAYCCNAARCAYCAYGAYCARGARTTYGCNCARTGGAARCARCAYGAYAAR GARGTNGTNGARGAYCARTTYAARGAYGAYYTNGARAARGCNYTNYTNGARAGYMGNYTN CARATGGARCARAARAARACNGARGAYAARGARAARCARGARMGNATHGAYGCNGGNGTN GARGTNCCNAARACNMGNGARGARMGNAARAARAARAARCARAARGAYAARGCNAARCCN ATGTCNYTNGARGARTTYAARCARYTNCCN------AARCCNACNTCNAARGCNYTNAAY TCNGAYGGNTCNGAR---GARGARTCNTCNCCNCCNCCNGTNCAYTAYMGNYTNCCNTCN TCNGARCARGAYTCNAARTTYTTYAAYAAYGTNCAYAGYGARGCNGARCARATHYTNMGN CARGAYAARATGCARGARGARTAYMGNAARACNTAYGCNGTNGAYAAYGCNGTNGTNGCN AARYTNAARAAYGAYATHGARGTNMGNGAYAARACNATHGARGARYTNAAYAGYAARATG GARAARATGGARGCNGARATGAARCARGTNAARCAYMGNAAYAARCARYTNTGYGTNATH YTNGCNCARGGNGARATGAARGAYAARGCNCARGTNYTNYTNCARGTNGAYGARYTNAAY ACNGTNAARGAYGARYTNATGGARCARGTNACNTCNYTNACNGCNGARYTNGARAARGAR AARTCNAARAAYAGYGCNYTNAARACNGARTCNGAYAARYTNAARGGNGGNMGNCAYGGN AARGAYAARGCNATHGARAARATHTTYAARGTNCARCAYCAYGARYTNGTNTGYGCNGTN TCNTCNAARCCNTAYATHTTYGAYAARGARAARAARGTNGTNGCNTCNYTNGAYAAYAAY TAYTTYTGGTGYAAYTTYTGYTCNTTYTCNTCNTCNAAYAARTCNYTNATHAARTTYTGY CCNTAYGARTCNTTYTGYMGNTCNGAYATHYTNMGNCAYATGGGNAARATGCAYGARGAR TTYGARGARATGTCNAAYAAYYTNAGYTAYTGYACNTTYYTNTCNGAYTAYATHMGNTGY AARACNMGNGCNGAYGGNAARGARAAYAAYGARCCNGTNGAYCARGAYGARGAYATHGGN GAYYTNGAYTCNGAYACNATG--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GGNGGNAARGAYAGYTGYTTY AAYATGATGACNTGYATHGCNGARGGNCAYGAYATHGTNGCNYTNGCNAAYYTNMGNCCN GARAAYAARGAYGARYTNGAYAGYTAYATGTAYCARACNGTNGGNCAYCAYGCNATHGAY YTNTAYGCNGARGCNATGGARYTNCCNYTNTAYGTNMGNACNATHAARGGNTCNAGYYTN TGYATHGGNMGNGAYTAYYTNCCNCARGARGGNGAYGARGTNGARGAYYTNTTYCARYTN YTNTCNCARATHAARACNGARAARGAYATHGARGCNGTNAGYGTNGGNGCNATHYTNTCN GAYTAYCARMGNGTNMGNGTNGARAAYGTNTGYCARMGNYTNGGNYTNAARGTNYTNGCN TTYYTNTGGAARMGNAARCARGARGARYTNYTNAARGARATGATHGAYTGYGAYYTNAAR GCNATHATHATHAARGTNGCNGCNYTNGGNYTNYTNCCNGAYAARCAYYTNGGNATGGAR YTNAARGAYATHTTYCCNCAYATGATHAARATGMGNGARAARTTYGGNYTNAAYGARTGY GGNGARGGNGGNGARTAYGARACNTTYGTNTAYGAYTGYCCNYTNTTYAARAARTCNATH GTNATHGARGARAARGARYTNGTNATHCAYTCNGAYGAYGCNTTYGCNCCNGTNGGNTAY YTNAAYYTNAARAARTGYCAYYTNCARGARAARCCNGGNCAYGAYGTNGCNTCNTTYYTN AARCAYGTNGAYGARATHCCNYTNTCNACNACNTCNAARTGGYTNTCNAARTAYYTNACN CARGAYGAYAAYGAYGAYCAYTCNCARYTNGGNATHAAYATGGGNGCNGCNGTNAAYACN YTNGARCAYGGNGTNTCNACNGARAARGARTTYCCNCCNTTYTGYGCNAGYGAYGGNATH AAYTTYCARGTNGCNGGNATHMGNTCNACNATHGGNATHACNTCNGAYGTNTCNGTNGCN GCNACNATGTCNATGGAYTCNYTNAARGARTGYGTNGARAARYTNGGNCAYCARATGTCN GAYATHACNTCNGTNTCNGTNTAYGTNGGNAAYATGTCNAAYTTYGCNYTNATHAAYGCN GTNTAYAARAARTAYTTYGARGTNAAYCCNCCNATHMGNATHTGYATHCARGTNTGYYTN TCNCCNTCNGTNYTNTTYCARYTNGAYTGYGARGGNACNAARAGYGARAARGARGAYMGN AARACNATGTAYGTNCARAGYYTNTCNYTNTGGGCNCCNGCNAAYYTNGGNCCNTTYAGY CARGCNACNTCNGTNAARGGNACNATHTTYGTNTCNGGNACNACNGCNYTNGTNCCNTCN ACNYTNAARYTNATHAGYGGNGGNATHTCNGTNCARAGYMGNGTNGCNYTNATHCAYYTN ATGGARAARTTYGARGGNYTNTGGTCNGCNTGYACNYTNAGYAAYTGYCCNYTNGTNAAY TGYTAYGTNACNCARMGNGARCAYATHCCNATGGCNAARATHGARTTYGAYATGATHYTN GARGARAGYAARCARAARYTNGGNACNGTNGGNYTNTCNCCNTCNGTNCARTAYTGYGTN GTNCCNMGNYTNCCNCARGGNGCNYTNGTNGARTGGCARGCNTAYGCNTGGGTNTTYACN GAYTCNGAYGARGARAGYATHCAY---AGYTCNCARTTYACNAARACNTTYCAYCAYTAY AGYYTNGARTTYGTNTGY---------ACNAAYCAYTTYTCNTGYMGNATHGARGCNTGY TCNTCNACNCCNGAYAGYGTNGAYGTNCARGARATGGCNTGYAAYYTNYTNMGNGARTAY AGYACNGTNATGGGNACNCAYGAYGGNGTNACNMGNGGNGGNYTNGCNAARATHTTYTAY ACNGCNGGNMGNTTYTCNAAYACNGARYTNGTNGARAGYTTY------ACNATGACNTCN CCNGTNAAYMGNGAYAARATHCCNGCNYTNTCNTTYATHCCNGTNATHGGNYTNAARACN GARCARAAYYTNYTNGTNTGGTGYCARTGYGTNCCNTGYTCNAARAAYGTNCARGTNAAR ATHMGNAGYAARAAYAAYTTYTGYTGYACNGAYGTNAARACNCCNGAYGTNGGNGGNGCN TCNMGNYTNGCNACNAGYGCNGCNCAYYTNATGYTNAAYGTNAARCARACNAARGARAAY CARYTNMGNAAYGTNGARMGNCCNYTNGCNTGGATHACNCAYGAYCCNAARAARMGNTCN TTYGTNMGNAAYGAYYTNACNTAYACNAARGGNCAYATHGTNGTNCARTCNACNGGNGTN TAYCAYGTNTAYAGYCAYATGACNYTNAGYTCNGTNGGNAAYACNGAYTTYAARAARACN GTNGTNCAYTCNATHACNAARTAYTAYAARGAYAAYCAYMGNACNYTNYTNATHACNCAR ATHAGYYTNGAYGARGAYGAYYTNAARACNACNAAYYTNGARGGNTCNTTYGARYTNAAR GAYGGNGAYGARYTNTAYGTNTAYGTNAGYTAYCCNTCNYTNYTNAAYGAYGAYYTNACN GCNAAYGTNTTYGGNYTNTTYMGNYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AARAGYGARGGN CARMGNACNCARYTNTCNGAYCAYATHGARACNYTNGTNAARGAYYTNGARAAYMGNGAR MGNCARAGYGCNAARGTNATHAAYCARYTNAARGARATGTCNGAYAARTAYGAYGAYTCN GAYMGNCAYMGNTCNYTNATGTCNACNCARYTNGARGAYATHCAYCARAARYTNAARGAY GTNACNMGNGARYTNGARAARACNACNCAYGARYTNMGNAAYACNCARYTNYTNYTNGCN GARACNGARAARAARAARGAYGARTTYAARGGNMGNGCNCARGARACNGTNMGNCARTGG AARACNAARGTNAARCARYTNGARMGNGAYYTNGAYMGNCARAARTAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------MGNTTY GGNGAYMGNGTNTCNGGNGAYYTNTTYGAYYTNTCNGTNCARATGGARGCNGARCARCCN MGNYTNGARCARTTYAAYGCNTGGGGNCAYMGNGTNGAYMGNYTNATHACNTCNAGYGCN TGGAARAARATGAARGARGTNTCNGCNGARGARGGNYTNGTNGCNTCNGGNTAYGARMGN AARTTYGGNGARTGGAGYMGNYTNTAYCARTTYTCNAARTTYTAYYTNTTYGARCCNTCN GCNGGNYTNTAYACNTGYCCNYTNGCNATGACNAAYGGNGCNGCNMGNACNATHGARATG AGYGAYGARGAYMGNGARATHGAYATHGARAGYGAYGCNGAYGAYGARGAYGGNYTNAGY GCNTTYAGYTCNGTNGAYGAYAARMGNGCNCAYCAYAAYGCNYTNGARMGNAARMGNMGN GAYCAYATHAARGAYAGYTTYCAYAGYYTNMGNGAYTGYGTNCCNCAYGARGAYAAYAAR GTNAARAGYAAYTCNTCNAGYAARACNTCNMGNGCNCARATHYTNMGNCARGCNTCNGAY TAYATHATHMGNATGMGNGAYAARACNTCNCARAAYGAYMGNCAYATHCARATHYTNAAR CARCARAAYGAYGARYTNCARGCNCAR--------------------------------- ------------------------------------------------ATHAARGCNYTN CARAARTCNCARGTNGGNGGNAARGGNYTNATHAAYTCNAGYTTYYTNGAYGAYMGNGGN GAYGCNGAYTAYGAYAGYTAYGAYGAYGARCCNGTNGTNGCNTCNCCNCCNAARMGNAAR AAR------------------YTNAARTCNCCNTCNTCNGGNYTNMGNYTNGGNYTNTCN MGNAAYCARMGNGTNAARCCNYTNCAYAGYTCNTTYYTNATHGCNGGNYTNGGNAAYTCN CCNTAYCCNAAYACNMGNCAYAGYGTNGGNYTNAARTCNATGGAYAAYYTNGCNYTNMGN TTYGGNYTNAGYTGGGARAARYTNCARGGNMGNYTNGGNGGNYTNYTNTGYAARATHGTN ATGGAYGTNACNACNGAYAAYMGNACNGARATHTAYYTNTTYAARCCNAARTCNYTNATG AAYGTNTGYGGNGGNAAYGTNGCNAARACNGCNAARTCNYTNGGNGTNAARGCNGAYTCN ATHTAYYTNGTNCAYGAYGARYTNGAYATGGCNGTNGGNAARGCNGCNATHAARAGYGGN GGNAGYGCNMGNGGNCAYMGNGGNGTNATHTCNTGYGTNTCNTCNYTNMGNTCN------ ---------------ACNGTN---------------------------------YTNCCN MGNYTNMGNATHGGNATHGGNMGNCCNTCNGCNAARTCNGARGTNGTNAAYTAYGTNYTN AGYCCNGTNCCNGTNGARGARGTNAARGTNATHGARYTNTCNATHGARMGNGGNYTNGAY ATGATGYTNAARCAYATHGCNGAYMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AAYAAYAAYAAYAAYAAYGCNGTNAAYACNGTNCCN YTNTCNAAYTGGTTYGCNGARGTNGTNGARYTNMGNMGNMGNGCNGARGARTAYMGNAAR MGNGCNCARGGNACNCAYTTYTCNMGNGARCAYYTNGTNCARYTNATGGCNAARCARAAY GARTGYTGGGAYGTNCAYTCNCARGCNTCNTCNACNGTNMGNGCNYTNAAYYTNGARCCN CCNAARATHAAYAAYMGNCCNGTNAARGAR------------------------------ ---------------------------CARMGNAAYTCNCCNGTNYTNTCNGAYATHGAR GARGAYGTNGARGARYTNGTNGARTCNTCNAAYAARGARGTNAARAARAAYTAYAARTCN GTNGGNTGYMGNATHTCNMGN------------ATGAARGARAAYAARGCNGCNGTNTCN CARCARCARMGNAARATGAARGARCARGCNMGNAARGARAARGARATHGARYTNGGNGAR AAYGAYGAYGAYGGNGTNGAYGCNGAYGARGGNMGNCARCCNACNCCN---AARYTNAAR ACNAARACNTCNGTNTCNMGNCAYCAYYTNGAYYTNACNACNCCNGCNGTNGGNGGNGCN YTNYTNACNTGYCCNCCNTCNAARAGYAGYAARATGATHGTNACNTCNMGNTCNGGNGAY AGYTAYGTNACNGCNTCNGAYAAYATGGARGTNTCNCARCARCARAARAARYTNGAYATG GAYAAYYTNAARACNMGNCCNATHYTNGGNCARCCNTCNGGNGAYAGYCAYACNYTNMGN GAYGAYGAYGCNTCNTCNGAYMGNCCNYTNCAYACNMGNTAYGTNCCNTCNCCNGCNYTN GTNGGNAGYGAYGARGAYAARGARAAYGCNCCNACNAARAARAARYTNTCNAARACNACN MGNCCNAGYAGYYTNACNCCNGTNCARGARGGNGTNGGNAARACNCAYGTNAARTCNAAR CCNTTYYTNACNYTNGAYGAYATHMGNGCNAAYGGNAGYGGNGCNGTNGAYGAYGAYGTN ATGTCNGTNTCNATGATGTCNATHGCNTCNAGYTCNTCNYTNGCNTCNGARGTNYTNGAR MGNGCNMGNMGNMGNCARAARGARTTYTGGGGNAARGGNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARTCNGGN MGNAARCARTGGYTNCAYCCNTCNAGYGCNYTNGTNAARGGNCAYATHYTNTAYACNGTN AARTTYYTNGGNGARTGYAARGTNGAYAAYCCNAARGGNACNGAYGTNGTNAARGCNGCN ATHACNAARATGAARTTYAAYAARCAYATHAARMGNGCNGARGGNCARAARACNCCNAAR ATHGARYTNACNATHTCNGTNGAYGCNGTNAARATHATHGAYCCNAARGCNAARGTNATH YTNCAYCARTAYCCNYTNCAYMGNATHTCNTAYTGYGCNGAYGAYAARTCNGAYAARMGN ATGTTYACNTTYATHGGNAARTCNGCNGARAAYAAYGAYCAYTTYTGYTAYGTNTTYGAY AGYGARAARTGYGCNGARGARATHACNYTNACNATHGGNCARGCNTTYGARYTNGCNTAY AARMGNTTYATHGARTCNTCNACNCARGAYYTNGAYYTNAARAARCARTTYYTNGTNYTN CARAARAARGTNAAYTCNYTNCARTTYGARAAYGAYGCNYTNAARAARMGNYTNGTNGAR YTNGARAARYTNAARGAYMGNTCNGAYGTNGARCARTAYAARYTNAAYAAYCARYTNAGY GAYATHACNACNGTNAARYTNAAYYTNMGNGARAGYTCNACNGAYGARGAYGAYAGY--- CCNGTNGCNTAYGARCCNAAYACNCARGTNTCNGTNGTNGGNMGNMGNYTNGARAAYYTN GTNATGACNGARGARAAYGCNAGY---------------------CCNCAYACNAAYGGN AAYTAYACNTCNGCNGAYCARACNGGNGCN------------CCNATHYTNAGYCCNCCN CCNCCNAAYTCNMGNCCNTCNMGNAGYTCNAGY---------TAYTCNAGYACNMGNATG AAYGCNGTNAAYAGYGCNAAYAAYAAYACNACNGCN---------ATGACNGGNMGNCAR AAYCAYACNGAYGCNTTYGGNATGCARGCNTTYAAYCCNGCN---CCNCARTCNGARCAR GARYTNATGGAYATHMGNGAYGGNTTYAGYMGNGGNYTNTCNTTYGGNACNGAYGAYTTY AAYYTNGAYGAYYTNGAYCCNYTNAAYCARMGNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARGAYCCNTCNCARCARTCNCCNYTNTCNMGNGGNGTNAARMGN ACNCAYGARGARATHGARGAYACNAGYGARAGYTCNACNTCNCCNAARGCNTCNCCNCAR AARAAYAARAARMGNTGYTAYACNTGYAGYTGYAARYTNGARYTNGCNCARMGNACNATH GGNMGNTGYMGNTGYGAYCAYGTNTTYTGYCCNATGCAYMGNYTNCCNGARYTNCAYGAY TGYGARTTYAAYCAYAARGARGAYGGNMGNMGNGARGCNMGNGARAARATGGTNAARCCN ACNMGNCAYATGGGNACNTCNTTYMGNMGNGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGYTN GTNYTNCAYACNCAYGCNGTNCAYMGNATHTCNTTYATHTCNMGNGAYACNACNGAYAAY MGNGCNTTYGGNTAYATHATHGGNAGYGGNGAYGGNAAYCAYACNTTYTTYGCNATHAAR ACNGCNGCNGCNGCNGARCARYTNGTNYTNACNYTNMGNGAYYTNTTYCARGTNGTNTAY GARATGAARAARAARGARGTNGAYGARGCNAARGARAARYTNGARAGYGAYACNTCNAAR GAYGAYACNGTNGCNGARAAYGARAARCCNTCNGGNGARGGNTCNACNTCNGARGGNGTN CARACNCARGARGCNCARGCNGCNGARGGNGAYGGNATHTAYCAYGTNCCNCCNAAYAAY GCNCCNGTNAAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNAGYACNATHACNATGTCNGGNATHACNTGYYTNGCNTGYAAYGTNGGNTTYGARGAY GTNGARYTNGGNMGNATHCAYTAYAARACNGAYTGGCAYMGNTAYAAYYTNAARMGNAAR GTNGCNGGNYTNGCNCCNGTNACNYTNGARAARTTYGARGARMGNCARAARGCNCARGAR ------CARCAR---GAYTCNGCNACNAAYCAYGARAGYTGYGTNTGYAARCCNTGYAAY AARTCNTTYAGYACNTCNAAYGCNTAYGARAAYCAYYTNCARTCNAARAARCAYAARGAR GTNACNTCNGGNACNGCNAARTCNAARAARAARAGYAARAARAARATHGGNACNGCNTCN GCNAGYGGNYTNTCNTCNGTNYTNAARTGYCARAARGAYGTNGARGARAAYATGTCNGAR GAYGARGAYGAYTCNGAYGTNGARTCNTGGGAYAGYTAYGAYGARAGYATHATHGGNYTN GARGARTGYYTNTTYTGYTCNTAYATHAGYCCNTCNATGGARATHAAYYTNGARCAYATG ACNYTNGAYCAYGGNTTYTTYYTNCCNGAYGCNGARTAYATHTGYGAYYTNGARGGNYTN ATGTCNTAYYTNGGNGARAARGTNGGNGCNGGNCAYGTNTGYYTNTGGTGYAAYGARAAR GGNAARMGNTTYCAYAGYTGYAARGAYGTNCARMGNCAYATGGTNGAYAARTGYCAYTGY AARATHYTNCAYGTNGGNGARACNATHTAYGARTTYGCNGAYTTYTAYAAYTAYTCNAAR AGYTAYCCNACNACNGARMGNGARAAYCCNGARGCNGAYCCNATG---GARTCNGTNGAY ATHATGGARYTNGAYGGNGAYGGNTAYTCNATHACNYTNCCNTCNGGNGCNGTNATHGGN CAYMGNTCNYTNATGMGNTAYTAYMGNCARAAYYTNGTNCCNCARACNCAYGARMGNACN AARAAYATGYTNCCNAARATGYTNGCNCARTAYAARGCNYTNGGNTGGACNGGNGCNACN GGNTCNCARGTNGARCARMGNGCNAARGAYYTNCAYTAYATGMGNMGNGTNMGNGAYAAR CAYTTYATGAARYTNGGNGTNAARGGNAAYAAYYTNMGNCAYMGNTTYMGNAAYCCNAAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GCNTTYGAYACNYTNACN CARATHTGYTCNGCNTGYTGYTAYMGNTCNYTNGAYAAYYTNATHCARGAYAAYGCNGAY TAYYTNGTNAAYAGYGTNTCNYTNMGNYTNMGNCAYTTYAAYCARAAYCARMGNACNCCN MGNYTNYTNTGYGTNATGYTNMGNTAYTGYTCNCARGAYYTNYTNCCNYTNGTNGARCAY AGYATHGGNGARATHYTNGAYACNYTNGAYGAYCAYTAYTCNGAYGAYYTNGTNYTNTTY ATGCCNGTNYTNYTNGARYTNACNTCNGCNATHGGNMGNTGGTTY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GAYTTYCCNAGYACN YTNCCNGCNGAYYTNCARGCNGGNATGGCNTTYGCNGGNGGNGGNCCNGTNTTYCCNCAR AAYCARMGNGGNGGNACNTAYGGNATGCCNCCNTTYCAYATGAAYTAYTCNCARCARGCN TCNATGCCNTCNATGTCNAGYYTNCCNTCNAGYTCNTTYMGNAGYMGNTTYAGYGAYTTY CCNTCNGAYCARAGYCCNCAYYTNCCNATGCCNATHCCNTCNCCNGCNTCNGGNATGATH GCNGAYMGNYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AARATGAARATHGARATHATGTCNCCNTCNGARATH GGNCCNCCNGTNTCNACNGTNACNTCNACNGARCCNAARGGNCCNAGYYTNAARATGAAR ATHATGTCNGGNTCNAAYCCNATGGCNGCNCARGTNGCNATGGARTCN---CARGAYGTN GGNGCNAGYCCNACNCCNAARGGNAARAARTCNTCNAARAARGCNAARGCNGCNACNGAR AAY---------------AGYGAYGTNTCN---------------------------AGY GCNGGNGAYAGYGARAARGCNCARAARAARAARAARGTNTCNAARAARAARGARAARYTN ATHCARGAYGCNATHAGYGCNGCNAARCARATGCCNAAYYTNGCNGCNYTNGTNTCNTCN CCNCARACNCCNGCNYTNGGNYTNGGNGARTCNCCNTCNGTNGTNGTNAARCCNAGY--- ---------AARAARAARGCNAARACNACNTCNGGNTCNGCNAARAARGAYAAYACNAGY GAYTCNYTNGTN---------ATGGAYTTYGAYGAYGGNGGNATGGARGAYGARGCNACN YTNGTNATHGCNGARACNGARAARAARAARAARAARGCNGGNATGAARAARAARAGYCCN AARGARAARGARGGNATGTCNAGYCCNAARGTNGARAARCCN---AARAARATHCCNAAR MGNGCNCCNACNGCNTAYATGYTNTTYTGYAAYTCNCAYMGNCCNTCNATHGTNGCNGAR AAYCCNGGNATHGARTTYGCNAGYATHAGYMGNMGNYTNGGNGARYTNTGGCARACNCAR TCNAAYAARCARAARYTNCARTGGMGNMGNAARGCNCARMGNMGNATGAARAARTCNAAY YTNATHTCNACNGGNAARGTN---GGNAARGARTCNCARTCNACNACNGCNCCNCCNACN TCNCAYGGNGTNGGNACNYTNACNTCNACNAAYAARAARYTNGCNYTNATGYTNCARAAR AGYCCNGTNTCNACNATGGAYGARGGNCCNYTNAGYCCNACNAARAAYTTYAGYATHGAR CCNYTNGAYGTNGCNGCNCAYYTNAARYTNYTNGGNGARTCNYTNAGYATHATHGGNATG MGNYTNCARGARCAYAARGGNATGATHGCNGTNCARGGNAGYYTNTCNGTNYTNYTNGAY TCNYTNYTNTGYGCNTGYGGNCCNYTNYTNTGYYTNACNCARCARGTNCCNGGNATGGAY GGNTGYTCNCCNYTNATHCAYGCNCARACNYTNGAYAGYGTNGCNTAYGTNATGCCNGGN YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GGNTAYGGNGCNCCNCCN CCN---GGNTAYGGNGCNCCNCCNCCNCARGGNTAYGGNGGNCCNGCNCARCCNGGNTAY GGN------------------------------------CARGCNCCNTAYCCNCARCAR CCNTAYCARCCNGGNCARTAYCARCARMGNCCN---CARCARGTNGTNTAYATHMGNGAR GARMGNMGN------GARAARGAYAAYTCNGCNGARACNTGYTGYATHATHGCNYTNTGY AGYGCNYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGACNCARAARGCNTAYAGYAAYGGNTCNGCN TAYCCNGARYTNCARAARGAYACNYTNMGNYTNTAYAGYTCNMGNACNTGYCCNTAYGCN GARMGNGCNMGNYTNGTNYTNGCNCAYAARAAYATHCCNCAYCARGTNGTNAAYATHAAY YTNMGNGAYAARCCNGAYTGGTTYYTNGARAARTCNCCNYTNGGNAARGTNCCNGTNATH GARCAYAAYGGNMGNGTNYTNTGYGARTCNACNGCNGTNTGYGARTAYYTNGAYGAYGTN TTYCCNGGNGARAARYTNCARGCNCARGARCCNTAYMGNAARGCNTGYGAYMGNATHYTN YTNGARCARTAYGGNCARGTNACNTCNGGNTTYTAYGGNGTNYTNYTNAGYGCNGGNAAR GCNTCNAARGTNGARCARYTNATGAARGGNATHGGNTAYTAYGARMGNGTNYTNGTNAAR MGNGGNACNYTNTTYTTYGGNGGNGARAARCCNAGYATGYTNGAYTTYTAYYTNTGGCCN CAYYTNGARMGNATHCCNACN---AARATGATGGGNCCNTCNGTNGCNYTNGAYCARAAY AAYTTYCCNAARATG---GCNTGGTGGGARGCNATGACNCARGTNGCNGCNATHAARACN GARATG------------------------------------------------------ ------------------TTYGGNMGNTAYCCNMGNGARTAYAAYCCNAARGTNCAYGGN CCNTAYATGCCNGGNMGNTTYTAYGGNAARCCNGAYACNCCNTTYGGNCARGTNAARYTN GGNGARYTNGGNTCNTGGTTYGGNMGNMGNAAYAARAGYCCNCAYGCNGCNTGGGGNTCN GTNCAYMGNGCNTAYTGGMGNTGGGCNGCNAAYAAYYTNCAYGTNMGNCAYAGYGGNTTY GTNCCNATHGGNCARGCNGCNATGGTNYTNTCNATHACNTTYTTYGTNYTNYTNTAYAAR GARMGNAGYYTNCARCARGARYTNGCNGAYGTNMGNGARGAYATGGAYTCNACNAARGAR GARYTNACNGAYAGYMGNMGNACNGTNGCNGARYTNAARACNACNATHTGYGGNYTNGGN GAYGAYYTNAAYAARTAYAARCAYYTNCARGAYGARAGYACNGCNGAYATHMGNYTNAAR AAYGARCAYYTNAARGAYCARGARGCNGTNYTNGCNGARACNMGNCARCARYTNGTNATH TCNGARAGYCARYTNGARGTNGCNAAYGARAARACNGAYCARYTNGARTCNGCNGTNGCN GCNYTNAARCARAARTAYAGYCARGCNAGYACNCARATGGGNCAYYTNGARGCNACNGTN AAYACNYTNCARGAYAARYTNACNGARAGYMGNAGYMGNGARATHGAYAARGARCARACN GTNGARCARYTNMGNTCNGARYTNGARGGNYTNGAYMGNGCNTAYTCNGAYAGYAARGAY GARYTNAGYAARTGYGARGAYATGATHCAYCARYTNACNACNGARYTNGAYTCNTCNCAR AARGARATHATHTCNTCNCAYAARMGNATHAARGAYYTNGARGARACNGGNMGNGAYYTN MGNGARCARATGCARAAYGCNCARCAYCARGCNYTNCARAAYGAYGARMGNGCNCAYAAY TTYGARAAYAARYTNYTNTCNTAYCARGGNGARCAYAGYCAYTCNGAYMGNGARTTYYTN CARAARGARGARCARATHAAYTCNYTNGARTAYCARYTNGARGARYTNMGNAGYGARGTN GARTCNMGNCARTCNACNGTNGAYCARYTNAARTCNGAYYTNAGYATHACNCARTCNGAY YTNACNCARGCNMGNGARGAYAARAGYGCNGCNYTNAAYGARATHGAYMGNYTNGARCAR CARAGYCARCARYTNCARYTNAAYYTNGCNTCNGCNCAYCARMGNCAYAARAGYGARACN TGYMGNTTYGARGARCARGTNGCNTCNYTNGARMGNCARYTNTCNGARACNCARGCNGCN YTNMGNAAYGCNGARTGYGARATHAAYAAYAARGARGARCARGTNAARMGNAAYGARGCN GARATHGCNACNTGYMGNGAYGAYATHMGNAGYAARGTNGAYGARATHGARMGNYTNGAR MGNTCNYTNCAYGARACNMGNYTNGARATGAAYCARACNAGYATHCARTGYAARCARYTN GARAAYGTNATHGCNGARATGAARTCNGAYGCNGARAAYTTYMGNAARGAYYTNAAYGAR GCNMGNYTNCARTAYAARGAYTGYGCNCARGARYTNGCNCAYCAYGARGARAARYTNAGY YTNATGGARAAYAGYYTNCARTCNACNCARGAYCARYTNAGYCARMGNGTNACNGARATH GTNMGNCAYGARCARACNACNMGNAARCARCARGCNGARYTNAARGCNATHAARGARMGN GCNGARGCNTAYGARGARGARATGGARGARCARAARGTNATGATHGAYAARYTNMGNAAR GAYYTNGTNATGTCNAARGARGARTAYCAYCAYTCNGTNCARGARGGNATHGCNTAYAAR CARCARGCNCAYAARAAYGARYTNGARYTNAAYGGNAGYMGNGARCARGARAARATGYTN TCNGAYCARGTNGARCARCARGARCARATHYTNAAYCARYTNCARACNGARYTNMGNGCN GARMGNGARMGNCAYGGNGAYACNGTNCARCARYTNAGYGCNAGYAARAARAAYGGNYTN GAYYTNCARGCNGAYYTNGARGCNATGCARAARCARGCNMGNGARYTNCARGAYMGNGTN AARGCNMGNGARGARCARATGGTNMGNYTNMGNCAYGARATHGAYAAYYTNCAYCARAAR AAYMGNGARAGYAAYGARYTNATGGCNGARAARGAYGGNCARYTNMGNYTNGCNGARATG AAYYTNCAYACNGCNCARAARCARGCNAARCAYCAYGCNCARGARATHGGNMGNTAYGAR GAYACNYTNGCNCARYTNCARACNGAYCARGARAARYTNCARGARCARTAYMGNCARTCN TCNTCNAAYYTNATGGARGCNGAYAGYAARGTNCAYGARYTNAARGTNCARYTNACNACN YTNCARGGNCAYCAYAARGARGCNATGGAYCARYTNACNGAYAARGCNMGNCARYTNGCN GGNATHAARACNGARGCNGCNAARATGGCNCARCARAAYAAYTCNATGAARGAYGARATH ATGATHTAYGAYGARAARGTNMGNAARYTNCARCAYGARYTNMGNAARTCNCARGARATH AAYAARGCNATHGARGARGARYTNCARCAYTTYGARGARMGNTAYACNAGYYTNCARGTN GAYYTNGTNTCNAGYCARGARAARCARAARCAYTCNYTNCARGARYTNTCNTCNAARGAR GARGARAAYGTNGTNYTNAARGTNGARYTNAGYTCNYTNCARGARAARTAYAARACNGTN AAYGAYGARGTNCAYAARYTNACNAGYGARYTNGARYTNACNAARCARAAYTAYMGNAGY GCNACNGARGARATHTCNGGNYTNMGNGTNGCNYTNGARGARTCNMGNGCNAAYGGNGAY MGNYTNCAYMGNGARAGYGARYTNGTNGTNCAYAAYGTNAAYACNTGGGTNCARGARCAR AARATGGCNAAYGARAARYTNGGNAAYAARATHMGNGARCARAGYAARTCNATHATGGCN YTNACNTCNGARAARGARACNYTNYTNGARCARGTNACNAARYTNCARAARCAYTAYAGY AARACNMGNACNGARYTNGARGAYAARACNATHGARGGNGARAARYTNMGNGCNYTNCAR TCNCAYTCNGCNCAYCARCARATHATHYTNAAYCARYTNAARAGYMGNYTNGARGARCAY GARYTNGAYAARGAYCARGAYYTNAARACNAARGTNGCNACNATHGGNGAYYTNCAYAAY MGNYTNAARTCNAAYATHGARAGYATHCAYCARYTNAAYCARCARYTNAGYACNYTNCAR AARGAYAAYATHMGNYTNMGNAGYGARYTNGAYMGNGARATHTCNACNMGNCARAGYYTN GARATGCARGTNCARGGNAARGAYCARYTNGTNGARTCNYTNMGNTCNCARYTNGAYTCN AAYTCNTAYAARYTNYTNYTNGARAARGCNGARAGYTAYAARGAYCCNGARAARYTNGTN MGNACNACNYTNAGYAARACNGCNGARGARACNGGNGTNCCNGAYCCNCAYAAYYTNGAY AARTCNTAYTGGGTNCARMGNGTNGGNGAR------YTNTCNATHCARYTNCARCARAGY AGYGARTAYTGGTCNGAYAARGTNMGNGAYYTNTCNGARCARYTNGARAARGCNMGNACN GTNACNTCN---YTNAAYTAYGTNYTNMGNMGNTCNGARGAYGAYCARGAYGTNGARAAR GTNGCNGCNATHYTNGARAGYGTNGARMGNYTNMGNAARAGYCARGARTCNGARAARGAR GTNATHMGNAGYYTNATHGARACNAAYAAYYTNGTNGAYAARCARATHCCNTCNCAYTTY TTYMGNYTNMGNGARGTNTTYGARGGNYTNATHGGNCAYATGTCNYTNCCNTCNYTNGTN AARAGYGTNCCNAARATGGCNGARYTNGGNYTNYTNGAYCCNMGNTCNCCNGAYGCNGAR AARGTNATHGAYMGNYTNAARGAYGCNAARGCNTTYGARCARGARMGNGTNTCNCCNGTN GCNGCNTTYGTNTCNATGMGNAARTAY---------------------AAYGTNCCNACN GARYTNGTNGTNMGNAARMGNACNMGNGGNCARMGNGAYMGNYTNMGNCARATGMGNCAY GAYAAYMGNMGNGTNACNGTNCARGGNYTNGCNAAYCAYCAYCARGCN------TCNTCN GGNYTNTAYGAYGAYAGYYTNTCNGAYTTYAGYGAYAGYTCNMGNACNGARGTNTCNGAR AAYYTNGTNTCNGCNTAYAARAAYATGACNAARGARGARYTNYTNMGNGTNGCNATHCAR ACNAARGCNCARATGATHMGNAARGAYCARTAYATHAARGAYYTNGARAAYTAYATHGAY GAYYTNYTNGTNMGNGTNATGGARACNACNCCNMGNYTNYTNACNMGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AARGCN GARCCNGGNTTYTTYMGNAARTCNTTYGCNTCNTTYMGNGCNATGMGNAARCARGCNAGY MGNAAYAARGARAARGAYAAYMGNCARAAYGARCCNATGGAYGARAAYGAYAARTGYYTN GTNTGYCCNTAYCCNCAR---TCNCARATHGTNGAYAARAAYGGNTCNCAYAARAARCCN TCNAARCARTCNAARAARGARTTYAARAGYTTYATGAARTCNAARAARAGYAARCARCAY TCNTCNTCNACNCARGAYGTNTCNTGGTAYTCNGAYAARGAYAGYAARATHATHCAYMGN AGYCAYCAYGCNTGYAAYYTNGARAGYACNCCNTAYGGNGCNTGGAAYCARTTYCCNGTN MGNGARTGYTCNATGGARACNTCNATHTCNMGNCARAAYGGNTCNMGNGAYGCN---ATG GAYCARCARCAYYTNGARACNGCNTCNYTNTCNGGNTAYGAYTCNGAYGTNACNAARAAY AARACNAGYMGNTCNMGNTCNMGNATHAARACNAAYCCNTGGYTNCCNTCNCCNCARCCN TCNYTNACNATGGGNMGNMGNGTNGAYAAYTGYMGNTCNMGNGAYTTYAAYGAYGAYTCN ATGTGYTTYCCNMGNTCNGCNYTNAAYGAYYTNAAYACNAARYTNACNAARAGYMGNCCN AAYTCNATHATHTCNCCNAAYACNGARTTYATHGCNYTNGCNGAYAAYATHGARCARYTN GCNAAYAAYATHAGYTTYGARTAYGARGAYAAYTTYAAYGCNTCNYTNGGNAGYAGYCAR GCNTTYGGNATGGTNGGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNGAYCCNAGYGAYYTNGCNTCNMGNYTNACNTCNGARGGNGARAARMGNTTY GGNGAYGARTCNGTNGAYGARGAYGAYGARTCNGARGARGAYGAYATHGAYYTNACNGAR GARGARAARGCNMGNAARAARGCNTTYATGATGAARMGNAARATGCAYTAYAAYGARTTY CARGCNGTNCARYTNGCNAARAARYTNATGGCNGARGAYAARGAYGAYGAYGAYGAYGAR GAYGARATGGAYACNMGNTGYGCNGGNGAYATGMGNATHAAYCAYTTYGAYATHGGNGAR ACNATHGCNCARMGNMGNMGNMGNGCNGGNGTNTAYAARAAYAAYTCN------------ ---------------------------GTNCCNACNAGYAGYTAYCARGTNACNMGNATG MGNAAYYTNTCNGGNGGNAGYAGYGGNAGYACNGCNAGYGGNAGYAGYAGYGGNAGYTCN GTNCARYTNGAYAAYCARTAYTCNTCNACNGAYAAYCAYYTNTAYTTY---TCNYTNGAR ATHTCNCCNTTYGCN---AAYTCNTCNGCNGTNCCNCARCAYAGYGAYGAYTCNGCNTCN ACNTCNCAYMGNAARYTNGAYMGNAGYYTNAGYGAYAGYGAYAGYGAYMGNTCNGGNAAY GGN---------TCNCARMGNTCNGTNAAYTCNAGYMGNTAYAARACNGARYTNTGYMGN CCNTTYGARGARAGYGGNTCNTGYAARTAYGGNGAYAARTGYCARTTYGCNCAYGGNGCN CAYGARYTNMGNAAYYTNGCNMGNCAYCCNAARTAYAARACNGARYTNTGYMGNACNTTY CAYACNATHGGNTTYTGYCCNTAYGGNCCNMGNTGYCAYTTYATHCAYGARGAYGAY--- ---------------------------------------------AARGGNGARTGYGCN CCNAARAGYAAYAGYGGNACNAGYAGYCCNTCNYTNAGYCCN------ACNGTNAAYGAY CAYAAYGAYTTYTCNTAYTGYTCNGARTCNTCNCARYTNAAYATHGARAAYACNCARATH AAYAAY---------TCNYTNACNGTNAAYATHAAY---TAYGGN---------AAYGCN GAYYTNCARCARGARCAR---CAR---TTYAAYTCNGCNYTNAAYYTNAAYMGNAAY--- ------------------AAYAAYGARTCNMGNAAYGTNTTYAAYAAYAAYTCNACNTGY AAR------GCNTCNGAYGARTAYGAYATHTTYAGYTCNATHTCNGTNTTYAAYGCNGAY GARGTNGTNGTNGAYAAYGCNCCNAARCCNTCNAAYTCNTCNTAYTCNTCNCAYTGYAAY CAR------AAYYTNGAYAAYCAYCCNGGNTAYGTNAAYACNTCNTGYTAYTGGCCNTCN ------AAYATGTCNTCNCARAGYATGGCNCCNGTNGAYCCNTAYAAYTAYTCNCCNACN GGNTCNACNGGNTCN------------------------AGYAGYAGYGGNAGYGAYTGY AGYGGNAGYACNGARAGYYTNGTNAGYTCNGGNTAYAAYAAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AGYGTN TAYGTNTGYTCNGGNCCNYTNTTYYTNCCNGTNGARGAYGGNAGYAARATGGTNAARTCN TTYGAYGTNYTNGGNGAYGGNGARGTNTCNGTNCCNACNCAYTTYTTYAARGTNATHGTN ATHGARACNGARGAYGGNCARYTNGARYTNGARTCNTAYATGYTNCCNAAYAAYAAYGGN GARGGNGGNGGNGARACNAAYYTNGAYGARYTNYTNACNCCNYTNTGYCARATHGARCAY CAYTCNGGNYTNATHTTYTTYCCNGAYAARAAR---TGYTTYAGYAGYAAYAAYAARMGN MGNGGNGCNAARYTNCAYGCNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARTAYTTYCAYGTNATHCCNCCNCCNCCNCCNYTNATGGARAAY GTNTTYGCNGGNMGNMGNGAYGTNMGNGAYCCNAGYTCNGTNCCNGARAARGARATHGTN AGYCAYAARGGNACNGTNMGNGGNTTYACNAAYMGNGTNMGNGCNGGNATHGCNACNTTY TGGGCNCARCCNGARGAYGARMGNAAYTAYMGNAARCARGARAARGGNAARATHGTNGTN TAYGCNACNTCNATGAGYGTNGTNMGNCARACNAGYGARMGNTGYAARACNGTNMGNAAY ATHYTNCARAAYCAYATGGTNMGNTAYGARGARMGNGAYYTNTAYATGAGYMGNGARAAY CARYTNGARYTNAARCAYMGNYTNAAYCARGARGGNGTNGGNAAYATHMGNYTNCCNCAY ATHTTYGCNGAYGGNATHYTNYTNGGNGGNGCNGGNGARYTNGARMGNYTNAAYGARATH GGNGARYTNMGNGTNYTNYTNGARGGNTAYCARAARATHGAYGTNAARYTNGCNTGYGAR MGNTGYGGNGGNTAYMGNTTYGTNCCNTGYGAYGTNTGYCAYGGNAGYAARMGNTCNYTN ATHMGNAAYCAYTTYACNGCNGAYTTYTTYGCNYTNMGNTGYATGCAYTGYGAYGAYAGY GGNYTNMGNMGNTGYGARYTNTGYAARGARCARCARGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TAY MGNCCNCAYGGNGTNYTNYTNCAYGGNCCNCCNGGNTGYGGNAARTCNTCNTTYGGNAAR AGYTTYGCNMGNAARTGYGCNGCNATHTTYTAYAAYGTNGAYTCNTCNAGYYTNYTNAGY TCNGAYTTYGGNAGYGGNGCNAAYGCNYTNAARAAYATHTTYCARAARGCNATHTCNYTN ATHGARGARGGNCCNGTNATHYTNTTYYTNGAYGARATHGAYACNYTNTGYCCNMGNCAR GARGTNGCNAGYYTNGGNAAYMGNCARYTNAGYAAYGCNYTNATGAAYGARATGGAYGCN ATGCARAGYCARAAYATHTCNGGNYTNYTNGTNYTNGCNGCNACNAAYTCNATHTCNAGY GTNGAYCCNCAYYTNMGNMGNCCNGGNMGNTTYGAYCARGARATHYTNATHAAYGTNCCN ACNGARGTNCARMGNYTNTCNATHATHCARGTNACNACNGCNCAYYTNTGYYTNGCNTCN GAYGTNTCNTGYAARACNYTNGCNCARATGACNCCNGGNTTYGTNGGNGCNGAYYTNAAR AGYYTNTGYGARGARGCNATHAGYCAYGCNCAYAAYAARAAYTCN---------CARGAR CCNGTNATHAGYATGGARGAYTTYGAYTAYGCNYTNCAYAARACNATHCCNTCNYTNAAR AARGGNGCNGARTGYGTNGTNGAYYTNAARCCNGTNAARTGGGCNGARATHGGNAGYYTN GAYGAYGTNAARGCNGARYTNAARCARTCNATHGARTGGCCNYTNAARTAYCCNGAYGTN YTNMGNAARATGGAYATHCCNCCNCCNAARGGNATHYTNYTNTAYGGNCCNCCNGGNTGY TGYAARACNACNYTNGTNMGNGCNGCNGCNACNTCNTGYAAYGTNACNTTYYTNTCNYTN AGYGGNGCNCARGTNTAYTCNGCNTAYGTNGGNGARTCNGARMGNYTNATHTCNCARGCN TTYCARAARGCNMGNGCNYTNGCNCCNTCNATHYTNTTYTTYGAYGARATGGARTCNYTN GTNGGNAARMGNATGGCNAAYGTNGGNAAYAAYMGNGTNCARGARMGNATHYTNTCNACN ATGYTNAAYGARATGGAYGGNGTNGGNAAYAARYTNGAYTTYAARATGGAYTCNACNACN GTNCARGCNGAYGGNAAYGGNTCNGCN---------------------ATGCARAARACN YTNGGNAAYAAYATGAAYGAYACNAGYTTYCCNGCNGARYTNACNGARTAYAGYAAYAGY AGYAGYYTNMGNGTNATHGTNGTNGGNGCNACNAAYMGNCCNGAYATGYTNGAYCCNGCN ATHYTNMGNCCNGGNMGNYTNGAYAARCAYATHTAYGTNCCNCCNCCNGAYGCNCARGCN MGNAARACNATHYTNGARATHTTYACNTCNAARATGTCNTGYACNGAYGTNGAYATHGAY TCNYTNGTNGGNAARACNGAYYTNTAYAGYGGNGCNGAYYTNAARAAYYTNTGYAARGAR GCNGGNYTNCARGCNGTNMGNGGNCARYTNGCNTCNAGYGAYAAYCARCAYCAYTTYGTN ATHACNGAYCAYCAYTTYCARCARGCNYTNGARAARATHAARCCNTCNYTN--------- ------------------------------------------------------------ ------------------MGNGTNTGYMGNGAYAAYGCNYTNYTNACNACNAARYTNGAR GARMGNAAYGARGARATGMGNMGNATGATHGCNCAYAARACNGCNATHGCNMGNGARMGN GAYGARYTNYTNGCNYTNYTNGAYGTNACNGARMGNATGAARTAYGARCARGGNAARAGY ATGATHGCNGARGARGARTAYGGNTCNTTYTCNTCNACNGARYTNGCNGTNYTNGGNGCN TGYAARTGYMGNGGNGCNAAYCCNGARCCNTGYGGNTGYGCNCAYGCNGCNGCNAAYYTN MGNAARGARGTNGTNAARYTNMGNGARGARATHATHATGACNAAYAARMGNMGNCARGAR GCNGARGARCARATGGCNAARAGYMGNCARATGAGYCARCARYTNGCNTCNATHTCNACN YTNACNTCNMGNTCNGTNAARGCNAARGCNGCNATGAARTTYYTNYTNAARACNYTNAGY AGYGAYGAYGARGARGCNTTYCCNTCNATHACNACNAAYCAYTAYGARGARAGYMGNAAY GTNTCNCARGAYMGNATGACNYTNCARGARYTNGTNCARGCNYTNACNGAYGTNGTNCAY GARAARGARGARGCNYTNGCNCARCARAARYTNGCNGCNCARGTNYTNGCNAAYAARYTN GGNGARYTNGARAAY---------------------------------------YTNTAY TAYAAYCAYYTNYTNGCNACNAAYATHATHACNTGYGGNAGYYTNYTNGGNGTNGGNGAY TTYATGGTNCARAARATHGGNTCNYTNTAYGAY---AARACN---GARTAYAAYTAYGCN MGNACNGGNMGNATGATHGTNGTNGGNTTYGGNYTNGGNCCNTTYAAYCAYTAYTGGTAY TCNTTYYTNGAYAARTTYGTNAARGGNMGNGGNATGAARGTNGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARCARCARGAR YTNMGNGARCAYGARGCNGARATHGTNGAYAARYTNATHGGNAGYCARGTNTCNATHTCN CARAGYGARAARGAYMGNATHATGAARGARCAYGARAARCARATGGTNAARYTNGARAAY AGYYTNACNYTNTCNAARYTNAARCARMGNMGNATGYTNGARGARAARATHGCNCARAAR MGNGGNMGNCARATGGARGARYTNGARAARMGNCARAAYGCNGARYTNCARAARCARMGN MGNATHGCNGARAAYAAYGGNGARGAYGARGAYGARGAYATHCARMGN---CARGTNGAR ACNATGAARAARCAYGTNCARCARAARATHGAYYTNGCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TCNGARGARGARAARGGNATGTCNATHTTYYTNGAYGTNTTYMGN MGNGCNGAYAARAAYGAYGAYGGNTCNATHTCNTGGGARGARTTYGTNTCNTAYTTYGCN GAYGGNGTNATGGGNAARGARGARYTNCARGARYTNTTYAAYGARATHGAYTCNCAYAAY ACNAAYAAYATHGAYGTNGGNGARYTNTGYGCNTAYTTYTCNCARCAYYTNGGNGARTTY CARGARGTNTTYGGNYTNGTNGARGARATGAAYAARAARYTNACNAGYGTNYTNTTYAAY ACNTCNAARGTNTAYAARGAYTCNTCNMGNACNGAYAARTTYATHACNMGNTTYYTNATG MGNGARAAYYTNAAYCARYTNYTNGCNYTNCARMGNCCNYTNGAYGCNGCNGCNGARGCN YTNGAYCARCARGCNMGNGARGARMGNTCNGAYATHCARCCNATGGCNGTNGGNGAYATH ATHAARAAR---TCNGGNAAYAGYGGNATHATHCCNGGNMGNYTNGTNMGNMGNGCNAAR MGNCARGTNAGYAAYATGAGYAAY---------------AAYTCNYTNGTNCCNGAYGGN CARGCNATHYTNTCNGGNCARYTNGAYAARYTNGCNAGYYTNATGGAYAARYTNGARTCN AARATHAARTTYGARAAYTTYMGNGAYGARGARGTNGTNACNTCNGGNAAYGAYACNGTN YTNYTNGTNCARMGNGAYTTYGTNGTNAARGARGAYGGNATGACNGAYTTYMGNGCNCAY YTNMGNTCNTAYGTNGAYYTNACNCARGGNTTYMGNGGNTGYTTYAAYGTNAGYGTNMGN GAYYTNMGNCCNTCNCAYTCNTTYCAYATHTAYGARGTNTGGTGYGAYGARGARCAYTAY YTNCARAAYTGYGGNAGYGARACNACNTCNTCNYTNGTNAAYAAYACNGCNGCNYTNYTN GARAARCCNGARACNGTNAARTCNATGGTNATHCCNGGNTCNTGGTGGAAYCARGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHTTY MGNCAYGARCARAAYGAYCCNTTYCARGCNYTNTAYAGYCCNACNCARGAYTCNTAYAAY TCNACNAAYTCNTCNGGNGAYATHMGNACNTGYMGNTCNTAYGARACNATGGAYAARATG GAYGCNAAYYTNACNCAYCCNGAYATHMGNYTNTGYGCNTCNAGYCCNGGNATHTAYATH AARGAYCCNAAYGGNMGNAGYCCNGCNMGNTCNACNAAYACNAGYTCNGAYGAYAGYAGY CARGCNTCNGTNGCNGCNAARGCNAGYMGNATGGTNGAYATGYTNACNGAYGARAAYMGN ACNYTNMGNGARGARYTNGCNACNGCNACNGTNAARGTNTCNMGNYTNYTNAARTTYGAR ATHGARGTNCARAARATGCAYGARGCNCAYGARTCNYTNYTNCARTCNCAYCARAARMGN GARACNYTNTGGYTNGCNATHMGNMGNAARYTNGARGARMGNATHCAYTCNYTNGARGCN GARGGNCCNGGNGGNAARGGNGCNGGNCCNGARAGYCAYAARYTNATGTCNATGACNGAR ACNGAYYTNMGNACNAARYTNGCNGARAARGARTCNYTNATHAGYMGNYTNYTNACNCAR AAYCARGARYTNYTNAGYGGNMGNAARCARYTNGARGCNGARAAYGTNCARYTNAAYGTN AGYYTNGCNGARCARAARGCNCAYGTNGARATHGTNGARAARGCNYTNGTNAAYAGYCAR GCNAARGTNYTNATGMGNGAYGARGTNTAYCARAARAARYTNTCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNCARCARCAYAGYCARTCNAGYYTNGAYAGYTAYGAYGAYGARGAYGGNCAR CARACNAAYATGAARATGGAYTAYMGNCCNGAYGAYGAYGAYGAYAAYGARGARGAYGAR AGYAAYCAYGGNGAYGTNGGNGAYYTNYTNGAYGARGCNATGGARTCNGAYTAYGAYCCN GAYATGGAYCCNAAYCAYGTNGTNYTNMGNAARAARCARGCNATHACNCARCARGARGAR TAYGAYCCNGAYATGGAYATHAAYAAYGTNGTNYTNMGNMGNAARCCNMGNCCNGCNAAR AARACNMGNAGYCAYGCNATGGCNYTNTCNACNGAYGAYGAYGARGAYGAYGAYMGNCCN TAYAGYYTNTCNGCNTAYMGNAARAGYGTNAAYGTNAAYCARTAYCAYATGGAYCCNATH GTNMGNCARAGYAARTAYTGYGGNCARAAYATHGTNGARGARGAYATHCARATGCCNTCN CCNACNMGNACNAARMGNGAYGAYMGNYTNGCNGTNCARGARMGNACNAARGAYYTNCAR GARYTNGTNCAYCARGARCARAAYGTNATHATGCARACNAGYAAYGCNYTNAAYAARTGY TGYATHGGNAAYGCNTAYTTYGCNGGNTCNGCNGARCARGTNGARTGYAAYMGNYTNYTN YTNATHGCNTGYCARAARMGNCARGTNTAYATGAARGARATHCARMGNYTNAARCARACN GGNGCNATHGAYGCNTCNGCNCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GCNCARATHATHGTNTTYCCNGARGAY GGNATHTAYGGNATGTTYTTY---AAYMGNAAYTCNATHYTNCAYTTYYTNGARAARATH CCNGAYCCNACNTCNATHTCNTGGAGYCCNTGYTCNGAYCCNATGMGNTTYTCNGGNACN GARGTNCARCAYGCNYTNAGYTGYATHGCNCARGARAAYAGYYTNTAYGTNGTNGCNAAY ATHGGNGAYTTYGTNCCNTGYAAYACNACNGTNGAYCCNAARTGYCCNGCNGAYGAYCAY TAYCARTAYAAYACNGAYGTNGCNTTYGAYCCNGAYGGNAARYTNGTNGCNAARTAYCAY AARTCNCAYYTNTTYTAYGARTTYCARTTYGAYACNCCNAAYCCNGARGTNGTNTAYTTY GAYACNCCNTTYGGNMGNTTYGGNATGYTNACNTGYTTYGAYYTNYTNTTYAARGAYCCN GCNGTNGTNATGGTNACNGAYAAYAAYATHACNAAYATHGCNTTYCCNACNGCNTGGATG GAYGCNYTNCCNTCNYTNTCNGCNATHGGNTAYCAYTCNTCNTTYGCNMGNGGNYTNGGN GTNAAYTTYYTNGCNGCNAAYGTNCAYYTNCCNAARMGNGGNTTYCAYGGNAGYGGNGTN TAYACNCCNGAYGGNATGTCNAGYTTYTAYTAYAAYAAYCAYYTNYTNTCNCCNGGNAAR YTNYTNGTNTCNACNGTNAAYATHGTN---------------------------CARMGN AARGARAAYGGNGTN------------------------------------------GGN AARGAYAAYYTNAARGTNAARAGYYTNGCNMGNGAR------------------------ ---------------GTNAAYAGYGTNMGN---------GCNGARTTYCARGCNGARYTN TTYGGNGAY---YTNTAYACNTTYMGNTCNYTNGAYGAYTCNTCNGGNAGYYTNAAYGTN TGYCARMGNAAYGTNTGYTGYTCNYTNACNTAYAAYATHTCNGGNCARYTNCAR---TAY GARYTNTTYGCNYTNGGNGTNTTYGAYGGNYTNCAYACNYTNGARGGNCAYTAYTAYTTY CARGTNTGYACNYTNGTNAARTGYGGNGAYMGNAAY---AAYAARTCNTCNTGYGGNTCN GGNACNAARATHTCNTAYACNAARTTYAARACNYTNTCNYTNACNGGNCAYTTYCARACN AARTTYGTNTAYCCNCARATHGTNYTNGCNAARGAYAARCARYTNYTNYTNGCNGAYCAR AGYTCNTGGAGYTTY---CARAARAAYACNYTNAARGCNGARTCNGGNYTNAAYGARCCN YTNYTNTCNGTNACNYTNYTNGGNMGNTAYTAYTGYMGNGAYAGYGAYTCNGGNAGYGAR GAYGTNGGNATGGGNTAYGAYGGN---CCNGGNAARMGNATGAAYGGNCAYTAYGAYGAY GAYGTNTGYMGNGAYTAYATGMGNAAYGTNTGYACNMGNGGNAARMGNTGYMGNTAYMGN CAYCCNGTNGCNGAYGAYCARCCNGAYCCNCCNCARMGNMGNGAYATHACNTTYTGYCAY GAYTAYCARAAYAAYGGNTGYAAYMGNAAYAAYTGYAARTTYYTNCAYTGYACNMGNGAY GARGARGARTGGTTYCAYMGNACNGGNYTNYTNCCNGTNMGNYTNAAYCAYGGNAAYAAY AAYGGNAGYTCNAAYCAYMGNGGNGGNGAYACNCCNYTNTGYAARGAYTAYYTNAAYGGN GAYTGYAARMGNGGNAGYAARTGYMGNTAYMGNCAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TAYAAYAGYYTNACN TGYGARGCNCARGARTTYATHAAYMGNATHGCNTCNATGGGNTTYYTNMGNGCNAARGTN TCNMGNGCNGTNCARAARTTYGGNCARGAYGARAARGARGTNYTNGAYCAYYTNTTYGCN GTNGAYYTNYTNGTNGARAARAARTAYGCNCCNATHCAYGCNGARGCNGCNYTNCARTCN TTYAARAAYGAYYTNGARAARGCNGARTCNTTYYTNAARATGCARACNCARYTNGARGAR YTNGGNTTYAAYAGYGARAGYGTNMGNGAYGCNYTNATHACNTCNAGYYTNGAYCAYGAY AARGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATHCARCARMGNTGGGCNAAYYTNCAYTCNTGYTTY ACNMGNGARGTNMGNGARCARAARAARAGYACNTCNGGNCARGCNGTNCCNAARMGNMGN AARTAYGTNTAYTTYAAYCARYTNYTNTCNMGNYTNCCNACNATHGARGAYACNAAYTTY ACNGAYGTNGGNTGYCARYTNATHGGNGCNTTYMGNAAYAARGAYTTYCAYAARACNYTN AAYGARATGATGCCNAAYAGYTCNTGGTCNTTYAAYGAYGCNATHGTNGAYGCNCAYGAY TCNAAYAAYYTNCARCAYAARAARCARGARGGNTAYGAYAGYGAYGTNGGNTGYCAYYTN YTNAGYTAYTTYYTNATHYTNAARYTNAAYYTNGGNTTYYTNAAYCARAAYCCNGTNCCN TAYAAYTTYYTNCCNGTN---------AARACNAAYMGNTGYATHATHGGNGARACNGCN GARATHATHGCNACNCCNTTYGGNAGYYTNTGYCCNGGNGTNTTYTTYAAYGCNTAYAGY MGNGGNGTNATHAGYAAYGTNAGYGGNGCNGAYAGYTGYTGGATHGTNACNGAYGCNMGN TGYATHCCNGGNTGYGARGGNGGNCCNYTNTAYACNAARMGNAARCCNACNGARTCNACN MGNTAYYTNACNGGNATHATHGCNTCNTCNYTNTGYTGGAARAAYAGYGARTGGGTNGGN TTYTCNATHGTNTGYGGNATHCAYAGYATHYTNAAYTCNGTN---ATGCAYTAYMGNAAR YTNTTYCCN------------------------MGNGAYAAYATHGGNTCNYTNACNACN ACNMGNAARCARCARATHAGYCAYTTYGTNMGN---GAYCARGAYCARGTNCARGCNGCN ACNGTNYTNATHCARTGYGGNAGYACNTGGGGNACNGGNGTNATHGTNGAYMGNAAYCAR GGNGTNYTNYTNACNTGYAGYCAYGTNGTNAARGAYGCNAAYTCNYTNTCNGTNACNGTN ACNCCNTCNAARAGYMGNTCNACNTAYACNGGNAARGTNGTNTAYATGCARGAYCCNGTN MGNACNCCNTAYGAYYTNGCNGTNATHAARTGYGCNGARGCNACNCARCAYYTNCCNAGY GAYTGGTCNATHCARGTNTCNAARGCNTTYGTNGGNCARGARGTNATHGTNTCNGGNCAY GCNGTNTTYAAYACNGAYTGYCAYYTNGARCCNTCNGTNTGYCARGGNGTNGTNTCNAAR GTNATHACNMGNMGNCAYCARCCNGTNATGGTNCARACNACNTGYGCNATHCAYGCNGGN GCNAGYGGNGGNCCNYTNYTNACNCCNGARGGNTGYYTNGTNGGNATHGTNGTNTGYAAY ACNMGNGAYTCNGCNAGYAAYTCNAAYTTYCCNCAYGTNAAYYTNTGYATHCCNGTNGGN ACNGTNTGGCCNGTNATHCARAARTAYYTNTCNACNMGNGAYAARCAYTGYYTNAAYCAR YTNCARGTNCARGAYYTNGARYTNACNCARYTNTGGGCNYTNGGNACNAARTGY------ ------------------------------AARAAYGTNAARGTNCARATHMGNGGNCAR AGYCARATHCARMGNAARAAY------------------------YTNGGNGCNAAYACN AARTTYCARAGYAARCCNGCNCARMGNACNTTYGAYGCNMGNTCNAARYTNGGNCCNAAR CCNATHGTNGAYGCNMGNGAYAARATHATHATHAAYAARAARAGYGGNAARGGNGAYGCN MGNAAYAARATHGTNCARAARCARGTNCARAARGGNACNTTYGAYGCNMGNTCNYTNYTN AARAAYCARGCN------------AARAAYAARACNAAYGGNGCNGTNAARCAYCCNCAR MGNCCNCCNATH------CCNGGNATHCARCCNYTNTCNYTNACNMGNACNYTNTCNAAY CCNGTNAAYATGGGNCARATHGGNAAYATHCARGTNACNMGNCARGTNCCNAGYACNGAR GTNTCNTTYTCNMGNGAYTCNATGCARATHACNAARMGNGGNGGNCCNCCNCCNCCNTCN GCNCCNACNATHGGNGAYGCNGTNCCNATHATHCARATHMGNAAYGAYMGNTAYCARCAR CCNCCNCCNCCNCCNCARCCNGCNTGGTCN---------------CAYCARCCNTCNCAR MGNYTNCCNCARCCNGCNCARTAYTCNCAYCAYAGYTCNTCNCCNTAYACNGCNACNAGY MGNCCNTTYAAYTCNTCNTCNACNCAYTCNCAYMGNMGNTAYCARGAYYTNGAYGAYCCN GCNTTYAAYAAYTCNTCNTCNATHGGNGTNCAYGAYATHCCNAARATGCAYATHTCNAAY ATHAARGCNGTNGARGCNGCNGGNATGMGNCCNGTNTCNTCNTCNACNACNAAYMGNTCN GCN---------CCNTAYMGNGCNCCNCCNGGNGCNGCNACN---------------YTN TCNTCNAARCARTCNATHCCNATGTCNCARCARTCNCARTCNGGNGCNYTNAARMGN--- MGNCARCCNGTNCARGARGTNGGNGGNCCNYTNMGNYTNGGNAARGGNGGNGGNCCNGGN YTNCARGTNGGNATHGGNGARGTNTCNCCNCCNAARMGNGCNAAR------GCNGGNACN YTNCCNTCNGARCCNATHGARATHATHGAY---GARGAYACNTCNAARTTYGTNAGYCCN ATHCARGGNTTYMGNGTNGTNGTNACNAAYYTNTTYTCNGGNGTNACNCARGAYGAYATH ATHGARYTNTTYGGNGTNGTNGGNCCNYTNAARAARGCNMGNYTNYTNAARGCNGGNTCN GCNGARGTNGTNTAYACNGTNMGNGARGAYGCNYTNAARGCNGTNCARAARTAYCAYGGN MGNGARYTNGAYGGNCARCCNATGTAYGTNAARATGACNACNCCNTCNACNGCNGTNGTN AARGCNCCNCARGGNCAY---GAYCCNGAYATHACNGGNGARGCNYTNMGNYTNTAYAAR AARCCNAGYAGYYTNGGNGCNYTNCCNGARGCNCCNATHGARGTNCCNACNATHCAYMGN GCNYTNTTYAARGTNGGNCCNCCNGCNCCNAAYAARTCNGTNAARTTYACNGTNAARATH GAYTTYATHCCNGGNTTYGTNCARYTNGTNMGNGARTGYATHYTNTCNCAYCARTGGACN AAYGCNYTNAARGTNGTNCAYGCNYTNGTNAAYGARGGNAAYAARGTNTCNAAYACNYTN TGGAARGCNGGNYTNGCNTCNYTNGGNAARAARCCNMGN------YTNATHGAYCARTAY GTNMGNCARYTNTAYAARATGTCNAARYTNTCNTGYGTNGARATHYTNYTNGAYTAYYTN YTNTAYYTNYTNGCNGARGGNAAYYTNTCNMGNGCNGARGAYYTNYTNCARGAYYTNAAR ------ATGTAYCAYYTNTAYGTNACNAAYGARAAYMGNGARTAYGARMGNATHYTNTTY YTNGCNTAYCARGGNATGACNAAYTAYYTNCAYTGGAARGCNGGNATHGTNGARACNCAY ATGGARAAYGAYGARAARGAYTTYATHAAYACNAARYTNTCNGARGAYTCNATGGTNAAR TCNTCNAARGTNACNGCNGARAARGCNCAYGAYAAYYTNTCNTGYATHGTNMGNATHCCN GGNGTNTGGGAYATHTTYATHGTNAARATGGTNGARATGCAYGARTTYTAYGAYGAYYTN GARACNGCNAARTCNYTNYTNAARGAYTAYMGNACNGARAAYYTNTGYAAYCCNAAYGCN CAYYTNTAYYTNTAYAAYTTYGARAARGAYCAYGARGGNAAYACNGAYGAYAARATHCAR AGYYTNACNAGYGTNATHAARYTNGAYCCNAGYAAYCCNYTNGCNYTNAAYYTNTAYAAR GARYTNGARTCNTCNGAYCCNMGNGCNATHTCNATHYTNTTYGAYTAYYTNGAYTTYGGN CAYTGYAARGAYGARATHGAYGCNTGGGARYTNYTNGARAARMGNYTNGCNCARAARACN CAYGGNAGYGARACNGARACNATHGTNAAYAAYTGYTGGATGTCNMGNAARGAYTGGTGG CCN--------------------------------------------------------- ---AARMGNTCNCCNGAYTGYTCNACNTGYAARGARATHGTNGAYAAYTTYCAYAARGGN YTNYTNGCNACNGCNAARTCNAAYTAYGGNGGNGGNAAYACNAAYTGGGARGARAARTCN YTNGGNTCNTAYGCNTTYAGYGARGTNMGNYTNGTNGARATHATGGARAAYYTNTGYAAR GAYAARTCNAARGARTGYCAYACNATGYTNGARGARCAYGARGAYYTNGTNGARAGYTTY TGGTTYAARGARTTYACNAARAAYACNCAYAARGAYTTYCAYATGTTYYTNTGYATHGAR AAYGTNAARGCNTGYTGYCCNAAYAAYACNTTYGGNAARGAYTGYYTNCCNTGYCCNGGN GGNGTNGAYACNACNTGYCAYGGNAAYGGNMGNTGYGAYGGNGARGGNACNMGNGGNGGN ACNGGNAARTGYMGNTGYAAYTCNGGNTAYACNGGNGAYGTNTGYACNGARTGYCARGAY GGNCAYTAYCARYTNGAYACNGAYGAYTCNAARACNGTNTGYAARGTNTGYCAYATHTCN TGYAARGGNAAYTGYGAYGGNGARGGNCCNGCNGCNTGYGAYGARTGYAARGAYGGNTGG YTNTCNGAYGAYACNCARGGNTGYATHGAYGTNGAYGARTGYYTNACNGARCCNTGYGAY GAYAAYCARTAYTGYGCNAAYACNCARGGNTCNTAYTCNTGYTTYACNTGYAAYGCNGCN TGYACNTCNTGYACNGGNGCNGGNCCNGAYAARTGYAAYGAYTGYAGYGARGGNTAYGTN MGNYTNGAYAAYGGNAAR---TGYGARGAYAARGAYGARTGYAGYYTNGAYAGYACNYTN TGYTCNAARCARAAYGARGARTGYATHAAYAARCCNGGNGGNTAYGAYTGYATHTGYACN ACNGGNTAY---GARTAYAARGAYGAYGARTGYGTNAARACNCCNAARGAR--------- ------------------------------------------------ATGGGNGGNACN GARAGYAARMGNMGNGTNGTNGTNGARGAYGTNAAYGGNGARGGNGTNGTNCARGTNACN GARGCNGTNGTNMGNMGNATGGAYTCNAARAGYGARATHACNAAYGCNGTNGARCARCAY MGNATHCARAAYGAYGAYCARYTNAARTCN------------------------------ ---------------ACNACNAARGARATHGARGAYTTYTAYATGGARAARYTNAAYGAY YTNCARAARMGNAAYCARGARYTNCARCARCAYTCNAAYGARCARTTYGCNAGYGCNGTN AARGARGTNGARCARAARTTYATGAARTAYACNTCNTCNCCNGTNTGYCARGAYYTNCAR ACNAARGTNYTNGARTGYTAYCARACNAAYCCNGAYTCNATHYTNGAYTGYTCNTCNGTN GTNAAYGCNTTYACNACNTGYGTNGAYMGNGCNMGNATGACNGTNTCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GAYYTNTCNGTNGCN TAYACNCARATHYTNCAYTAYGAYAARGCNGTNCARTGYAGYGARAARGCNYTNCCNYTN GTNGARGAYCCNAGYGGNGAYCCNMGNTTYGCNTCNATHATHTAYCARAAYYTNGGNGCN ATHTAYAAYTAYATGGGNMGNTAYGAYGAYGCNGTNAARTTYCAYCARAARGCNTGYCAY ACNTTYGCNAARYTNGGNATGMGNGCNAAYCARGGNCAYTGYTTYACNAAYATGGGNTAY GCNTAYAGYCARYTNAARGAYATGGAYAARGCNGGNGARTGYTTYYTNCAYGGNYTNCAR GCNGCNMGNGAYTGYGGNGAYCAYAARACNGARTGGCARAAYYTNGARGCNYTNGCNAGY GTNGCNTTYAAYAARAAYTCNYTNAARAARGCNGARCARTAYTAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TCNMGNGGNGAYTGYYTNAARGTNGAYMGNGTNATGATHTGG AAYGARTAYGARGCNTAYGTNGTNCARTAYAARCARATHGCNGTNTCNGCNTGYGGNCAR ACNGCNGTNYTNAAYGTNYTNAARGCNYTNAARTTYCARTGYGARAARTCNGTNGTNTGY AARGTNATHATHACNAAYYTNMGNAARGAYGAYMGNGAYATHCCNGAYTAYYTNTTYTCN MGNGCNTGYGCNGGNACNACNGCNGTNGARYTNATGTCNGGNGTNGARAARYTNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CAYTCNGAYTAYGARGARTCNGARGARGAYAAYATHYTNGCNGAYGARMGNTTYAAR AARMGNATHGAYCARGCNACNAARTGYGGNTAYTCNGAYGGNCARGTNACNAARGTNYTN AARMGNYTNGGNGTNGAYTCNAGYATGGAYGAYATGATGMGNGARYTNYTN---AARGAR CCNCARGAYGTNAGYGCNTAYGAYAAYATGGARCARACNGARACNAAYGTNYTNAAR--- ---------------------------------GGNGARGAYAGYGAYGAYAGY------ ------GARGGNTTYGAYGTNGAYGAYAGYTCNAAYYTNMGNCAYATHATHATHGAYGGN AGYAAYGTNGCNATGAGYCAYGGNCARAARGTNTTYTCNTGYYTNGGNATHAARATHGTN GTNGAYTGGTTYAARTCNMGNGGNCAYACNAAYATHACNGCNTTYGTNCCNCARTGGMGN AARGARGCNTCNMGNCCNGAYGCNCCNATHACNAAYCARGARATHYTNACNGARYTNGAR TCNGARAARATHGTNGTNTTYACNCCNTCNMGNMGNATHGGNAGYACNMGNATHGTNTGY TAYGAYGAYMGNTAYGTNYTNAAYYTNGCNGCNCARACNAARGGNATHGTNGTNTCNAAY GAYATHTAYMGNGAYYTNGTNMGNGARMGNGAYGAYTTYMGNCARGTNGTNGCNGARMGN YTNYTNATGTAYTCNTTYGTNCARGAYACNTTYATGCCNCCNGARGAYCCNYTNGGNMGN CARGGNCCNTCNYTNGAYAAYTTYYTNMGNATHAARCCNTCNGARCCNAARAARAARCCN CARAAYTGYCCNTAYGGNAARAARTGYACNTAYGGNAAYAARTGYMGNTAYTAYCAYCCN GARMGNMGNTAYGCNCCNCARAARATGGTNGCNGARAARYTNAARGARAAYGCNGARCAY AARGCNGCNAARGCNGTNGARAGYTTYAARGARAARGGNMGNMGNCCNAARCARAARYTN TCNMGNACNATHTCNATGYTNCCNCARGARTCNTTYGAYAARACNTCN------GAYGAY ATHTTYAARAARCCNCARYTNCAYCAYTCNCARTCNYTNGTNTAYCCNAGYAGYTAYYTN AGYGAYYTNMGNATGAARATGGAR---------GARGCNGARYTNGCNGARGARTAYAAR CCNGCNCAYTTYACNYTNAAYATGGGNCARGAYYTNAAYCCNCAYAGYAARCARTAYAGY AAYAGYTGYGAYCCNAAYTCNCARCCNTTYAARCCNGARTCNATHYTNTCNCCNGTNCCN AAYCCNTCNTCNCCNMGNGTNACNGTNCARTCNTCNYTNAAYATHCCNAAYTCNGAYTCN CARGAYMGNTAYYTNAGYGGNCAYYTNYTNGTNGTNAARAARYTNTCNGAYGARGAYAAY ACNAAYTTYTTYTCNCARCAYACNTCN--------------------------------- ------ACNGARGARGAYTAYAARAGYATGGAYAAYTTYYTNGCNGAYCARATGYTNGAY AARGCNMGNCARAARGCN---ACNAARACNGGNGTNAARTAYACNGTNCARGTNTCNCCN YTNGARATHGCNGAYYTNGCNGAYCCNTCNGTNCARCARATHATHMGNYTNCAY---GCN GTNAAYGTNACNTTYAARCAYCARGCNGTNAARTTYMGNAARAARAARGGNTTYGCNACN GCNTCNTTYGCNACNGTNACNGARYTNAARGARTTYGTNTAYCARYTNACNCARATHAAR GTNATHGARAARMGNATHGAYGTNGTNATHTCNYTNAAYCARCCNGAY------------ ACNYTNTCNTTYGTNATHCAYYTNGAYMGNAAYGGNAARYTNYTNAAYYTNATHAAYAGY GAYGARGAYCCNAARATHAAYAARCCNATHCCNGTNGGNCARAAYCCNCAYAARGTNGAR TTYGTNAARGTNCCNTGYGGNGCNAAYGGNGCNTTYATGCAYAGYATGTTYCCNTTYACN AAYAAYGTNYTNATHACNMGNTCNCARGTNGGNAARGARACNAAYCCNGTNTGYCAYGGN CCNGTNTCNGTNTTYTAYATHAAYTCNAARTGGYTNGARGCNGTNATGGAYTGYTGYTCN GAYTTYTCNGTNAAYGGNTTYACNYTNTCNGTN---------------AARAGYCAYTCN GARAAYAARGTNGARAARCCNATHACNACNGARACNGAYCARTCNAARMGNACNAARTCN TCNATGGAYGTNGAYGARTGYGGNTGYGAY------------------AAYGAYGCNGAY GAYTCNGTNACNAAYATGACNMGNGAYGTNTGYGCNGAYATGYTNGARTCNATHCARAAR YTNAARGARYTNGARCCNAAYAAYCCNAAYATGAARAARATHGTNGARATGCARAARCAR YTNAAYGCNYTNCARAAYTCNYTNMGNAARCCNYTNGGNTCNGTNAARAAYYTNCCNYTN AARGAYGAYAARYTNGCN---CCNYTNACN------------------------------ ------------------CCNGCNATHAARAARCARAARCARATGCARAAYYTNGARGAR ATHTTYGARGARACNGARMGNGCNGARMGNCARAARGARGAYCARATGCARCARCARMGN GARATGGARATGCARMGNGARAARGAYCARGARCARAARMGNMGNTCNCARTGGGCNMGN AAYATHYTNTCNGAYTAYAARMGNCARGGN------------GTNATHGGNGARAARGTN AGYGARGAYGCNGARAARATHYTNMGNCARMGNGAYCARMGNYTNAAR------------ ---GARCARMGNATHGCNGARGCNYTNAARMGNAARGARMGNGARAARYTNMGNYTNGAR MGNGARGARGARGARAARTGYAARGARATGGARAARMGNMGNYTNATHCARAARATH--- ---------GARGARACNMGNYTNMGNGAYTCNCARAARAARGAYAARTTYATGAAYCAY YTNYTNTGGGAYMGNCCNAGYTCNGAYAAYGARGCNTCNTCNCCNAGYMGNTAYGTNTCN GARTCNAARGGNAGYMGNMGNGAYAARGAYAGYTAYAARMGNGARAGYAGYMGNYTNAAR TCNGARGARGARTAYCARAARATHGTNGCNCARAAYYTNYTNCAY--------------- ---------ACNATHCCNACNAAYTTYAARGTNMGNGTNACNAGYATHGCNAAYMGNYTN TGYCCNGTNCARGGNTGYCCNGCNAARGTNTGYTTYMGNGAYATGGARTCNTTYATGGAY CAYTGGTCNATHTTYCAYCARGCNMGNACNACNATGMGNTTYTGYCCNAARTGYACNGCN TAYTTYATGGAYGCNGARGARYTNGARAAYCAYATHATGAARCAYCAYTGGYTNTCNTCN ---AAYGARGCNATHGARYTNGTNTGYAAYGCNMGNGTNAARGTNATHCCNAAYCCNAGY TTYMGNGAYCCNTTYCCNTTY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARTGGCARAAYGCNGTNAARAGYTAYYTNCAYCCNAARGCNCAR AARGTNAARTCNGTNMGNYTNGTNGGNATGATGYTNYTNGTNTAYATHCARGARAARCAY GTNCCNCAYATHAGYGCNATHGCNATGGAYTCNGTNGCNACNGGNATHATGGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNGAYTTYATHACNGARTAYAAYCCNAAYAAR--- TCNTCNAGYTCNACNAAYGTNTAYGARCARGAYGARMGNYTNGCNAAYTAYGARMGNTAY MGNACNYTNGTNGARAAYGARGCNTCNGGNYTNACNGARGARCARTGYYTNCAYCARATH TAYYTNGAYGARCAYTTYGGNACNATHAAYAARTCNAAYGARGARGAYAARAARAARAAY GCNGAYAARAARGCNGCNATHGGNTAYGTNTAYGARGAYAGYACNCCNGTNAARAAYGAR TCNATHGAYAAYAGYGARGARGARGARAGYGAYGAYGAYYTNGAYATGGCNGAYYTNGAY GTNACNATHGAYGTNGAYGCNYTNACNCCNGAYYTNTGYAARGARGTNAAYYTNATHGCN GGNCARTAYGGNATGGCNGAYGAYGAYTTYGTNMGNYTNYTNMGNAARGAYAARCARGAR YTNGARGCNYTNAARGARGCNMGNCARYTNGARGARGCNAARGCNCARTTYTCNGGNMGN AARTCNMGNMGNGARMGNMGNGCNATHAAYGARMGNMGNCARAAYCCNCARMGNTTYGGN MGNCCNAGYTAYGCNGCNMGNGAYAGYCCNAARTAYGARCCNTAYAARMGNCCNGGNTCN TCNTCNMGNTCNMGNTCNMGNTCNMGNTCNMGNTCNTCNGARMGNGCNGARGTNAARTTY ATHACNAGYTTYGGNGGNAAYGAYAGYGAYGARGAR------GCNATHATHCARGGNCCN TCNYTNCCNGCN---------ATGACNACNAAYMGNAAYCARAARAARAAYTCNGARTCN TCNAARTGYGARACNCCNTGGYTNGCNTCN---------ACNTCNAARAGYGARTCNAAR CARGCNACNGGNTCNAGYTCNMGNTCNTTYMGNCARMGNTAY---------------AGY AGYMGNTCN---------------TCNACNAGYMGNTCNMGNTCNMGNTCNMGNTCNAAR TCN---MGNTCNGAYAGYMGNMGNMGNTCNAGYTCNTCNTCNMGNTCNMGNAGYMGNTCN CCNACNCCNGCNMGNAAYGARTCNAARMGNTCNMGNTCNGTNGAYAARYTNCCNGTNAAR MGNTAYMGNMGNGARAGYYTNTCNTCNAGYTCNGGNYTNAGYAAYYTNGAYTCNGAYGAY GAY---TCNCARTCNTCNGCNTCNMGNCAYAARGCNGGNAGY------GAYAARMGNTCN AAYYTNGTNACNGGNGGNAARYTNAGYAGYAARAGYTAYTCNCARNNNAGYGTNGARACN CCNCARGARMGNYTNAARMGNMGNATGCARGCNCARYTNAAYAARCARTTYMGNGCNGAY AARAARGCNGARATHACNMGNATHACNAARCARGARCARGARMGNYTNGAYMGNGARGAR GARATHMGNACNYTNGCNATHGARATGMGNMGNMGNGARMGNGARMGNMGNCAYMGNGAR MGNGARGARGARGARAGYGARMGNMGNGCNMGNMGNAGYCARMGNCAYGTNAGYTCNAGY AGYGAYAGYAGYTCNMGNGAYAGYTCNMGNAGY--------------------------- ---------MGNAGYCCNCCNAARMGNMGNGAYGAYACNGAYTCNMGNMGNYTNAGYACN GGNGAYAGYMGNGAYAARAGYMGNGARMGNMGN------TCNYTNTGYGCNATHYTNAAR YTNGARCARCAYGARAARTCNAGYAARCARGCNGGNGARTGYYTNGTNYTNYTNAGYGGN GTNGARGCNMGNATHGARGAYMGNATGAARGCNTAYAARGCNAARACNGTNACNGARMGN ATHMGNAGYYTNGAYTAYAGYACNYTNMGNGARGCNGGNATHGCNTGYCAYCARATHMGN ACNTGYYTNAAYGARGTNTCNMGNATHATHTCNYTNGCNTGGATHACNGARYTNCCNYTN GTNACNGARGARGGNMGNTTYTAYGAYCCN------------GARACNGARAAYYTNAAR TCNGARYTNTCNGARYTNCARTTYAARTAYGAYYTNYTNGAYACNACNGTNAARGARCAR AARGGNAARYTNAGYGTNTCNAARCARMGNCARAARGAYTGGGARCAYTCNGTNTGYMGN CAR---------AARGGNAARMGNTCNMGNAGYYTNTCNGARTCNTTYGARGAYTTYAAY GGNYTNGAYGAYMGN---------------GAYATGYTN------------GAY------ ------AGYGAYATHGAYCAYGARAARATHGTNCAYATHAAYAAYTGYAARATHYTNAAY CCNGAYYTNAARGGNCARTAYGARCARATHAARMGNTCNTAYGCNAAYATHYTNTAYAAR TGGGGNYTNYTNAAYCARMGNACNCARATHYTNAARCAYACNGTNTCNATHCARGCN--- AGYAARAARGTNGARTTYTCNATHCCNTGYTCNAAYTGYTCNGAYACNGTNATGAGYGTN CARTGYAAYMGNTGYMGNTAYCCNTCNATHAAYTGYTCNATHTGYCAYATHGGNGTNMGN GGNCCNGCNAAYGTNTGYYTNGCNTGYGGNCAYGGNGGNCAYTCNAGYCAYATGATGACN TGGTTYCAYAAYAAYAGYCARTGYCCNTCNGGNTGYGGNTGYAAYTGYYTNCARGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AAYYTNTCNGARAARGTNGARGARYTNAAYCARCARGARCARAAR GCNTGYYTNYTNACNGGNGARYTNCAYTCNYTNAGYYTNAARYTNAARGAYGCNGARGAY ACNMGNGAYCAYYTNGGNTCNATGYTNTCNGARAARAARGGNGARGTNGCNGARYTNACN CARCARYTNMGNYTNAAYMGNGARCARATGCARAGYCARCAYGAYGAYYTNGTNCARTGY MGNCARTCNTTYTCNTGYGCNCARMGNGAYGGNGAYAARYTNMGNMGNGARATGGAYAAY GCNYTNGCNAAYYTNGARCAYMGNGARTGYGARYTNAGYMGNYTNAAYGARGARMGNAAR AAYYTNATGGARAARGTNGCNATGYTNACNTGYCARATGGARCARGARACNACNATGTAY MGNCARCARYTNTCNGARACNAARTGYMGNYTNGARAARGARYTNGARTGYYTNMGNAAY TAYTCNTGYCARYTNGARTCNACNAAYAGYACNYTNACNAAYAARYTNTCNYTNTGYCAR MGNCARGTNYTNCARGTNGARAARTGYTGYAAYCAYAARYTNGARTCNYTNAGYMGNAGY YTNGARGAYYTNAAYCAYAARYTNACNGTNMGNAAYGAYGARYTNATGTCNTGYMGNGAY AGYYTNGGNYTNAARGAYTCNGARATHTGYMGNYTNAARAARMGNYTNTGYAGYTGYGAR AARCCNTGYATGAAYGAYGGNAAYCAYAAYAAYAAYAGYGGNGARGCNGAYGARGGNAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AGYGAYAGYACN GCNYTNGCNGTNGTNYTNTAYAARGARGARAAYYTNYTNCCNCAYGARAARMGNAAYMGN AGYTTYACNATHGCNGGNCAYAAYTTYTAYATHGARCARGAYTGGMGNGCNGGNGGNGTN GCNGCNGTNGTNTGGGAYGCNGCNYTNGTNYTNGGNGARTAYYTNGCNATGAAYGTNCAY YTNGTNCARAAYMGNMGNATHYTNGARYTNGGNGCNGGNACNGGNYTNGCNGGNATGGTN GCNTCNTCNYTNGGNGGNGAYGTNATHGTNACNGARMGNGARGARGCNYTNTCNTAYYTN AARACNGCNGTNTCNTCNAAYAARGCNGGNAARAAYTGGAARATHAARGCNGCNGTNYTN GAYTGGATHCAYAGY------GTNGAYTCNAAYAARTGGAGYAAYTTYGAYYTNGTNATH GGNGCNGAYATHATHTAYATHGARAGYACNTTYTCNCAYYTNYTNAARACNYTNAARTCN GTNGCNAGYTCNCCNAARACNCARGTNYTNYTNTCNTGYMGNATHMGNTAYGAYMGNGAY YTNCAYTTYATHAAYATGYTNAARGARATHTTYATHGTNGARGARATHTTYTAYAAYGCN CARTTYGAYATHAARATHTTYTCNGCNATHTCNAAR---YTNGTNACNCAYTAYGGNGGN TGYCAYTGYGGNGCNGTNMGNTTYTCNGTNATGACNTCNGCNAAYYTNGAYGTNGTNGAY TGYAAYTGYAGYATHTGYACNAARAARCARAAYAGYCAYTTYATHGTNCCNAARGCNMGN TTYAARYTNACNCARGGNAARGAYTCNYTNACNACNTAYACNTAYAAYACNCAYAARGCN AARCAYACNTTYTGYAARATHTGYGGNGTNCARAGYTTYTAYACNCCNMGNTCNAAYCAR GAYGGNTAYGGNATHATGCCNCAYTGYYTNGAYCCNGGNACNGTNAARTCNACNAARATH TTYAARTTYGAYGGNAAYCARTGGGARAAYTCNATHAARCAYTCNAGYATHGCNGARTAY TCNAAR------------------TTYTGYTAYGGNACNYTNAARMGNGGNGARCCNAAY TAYGARCARATHACNAAYGGNGARAAYGGNGTNGCNATHTTYATGGGNTGYGGNGARACN GTNGARAARTAYCCNYTNGTNGTNGGNACNYTNTAYAAYGTNCCNTTYYTNATGAARYTN GARAAYCARGGNAAYAAYGTNCARGGNGARYTNTTYAARGTNGAYGAYAARATGYTNGCN CAYYTNGAYAARTTYGARTCNCAYCCNCAYYTNTAYYTNMGNCARGARGTNGTNATHAAY YTNACNGARGAYGARGAYGGNAAYCAYYTNGCNACNCCNMGNMGNGTNATHTGYTGGGTN TAYTTYATGACNAARAAYAAYAARAAYATGYTNCARYTNAARTGGATHTCNGAYTAYMGN GCNYTNTCNACNGAYTAYCCNGCNTAYGTNAARMGNTGYGAYMGNAAY---GCNGCNAGY TTYGARGAYACNMGNTGYAARTGYGTNTGYTCNAARACNAARGAYAAYAGYGGNAARGAR TCNMGNACNGTNTTYMGNAAYACNACNMGNAGYGARCARTGYGAYTGYGAYCAYGTNGTN MGNCCNYTNGCNCCNACNYTNTCNTGYTCNYTNTGYCARTGYAARACNGARACNMGNAAY ACNACNACNATHAARGTNGTNGTNATHTTYATHATHTGYGTNGTNTCNYTNYTNTTYGTN TAYATGYTNTTYYTNYTNTGYYTNGAYCCNYTNYTNCARAARMGNCCNGCNAARTCNTAY CARCARCAYACNAAYGARGARGTNAAYATGGARGAYYTNTCNCARMGNCCNGARCARGAR ---------------------------GCNGGNCCNTCNACNGARTCNYTNTCNGCNMGN CARMGNTCNYTNYTNAAYATHGTNACNAARGARCARAARAARTGGAARGGNACNGTNCAR GARCARMGNMGNAAYATHTAYGAYMGNCAYTCNATGYTNAAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MGNYTNGAYGAYYTNYTNAAYGAR TGGACNAAYAARTTYYTNGCNGARGGNATHACNGAYGCNGCNTCNAGYGCNGARTAYATH AGYGCNCAYGTNYTNGGNAARAARACNYTNCAYGAYAAYGAR---AARGAYGTNTAYYTN GAYAGYGAYGARGTNGCNTCNATHCAYAAYYTNTGYMGNYTNMGNTTYAARMGNATGCCN GTNCARTAYYTNYTNGGNGARTGGGAYTTYGAYGGNYTNACNYTNAARATGGCNCCNCCN GTNTTYATHCCNMGNCCNGTNACNGARGARYTNGTNGGNCAYTGYAAYGCNGTNYTNGAR TCNAAY------TGGTCNGTNTGYAARCARTAYCCNGTNTTYYTNGARATHGGNTGYGGN AGYGGNGCNATHAGYGTNTCNYTNYTNAARMGNTTYCARGARYTNAARGCNGTNTGYGTN GAYATHTCNTCNAARGCNTGYTCNYTNACNGARACNAAYGCNAARAAYATHGGNGTNAAR GAYMGNATHCARATHTTYCAYGGNAAYTTYACNCAYCAYGARGTNYTNTCNAARYTNCAY TCNYTNAGYCCNTTYTGYYTNYTNGTNAGYAAYCCNCCNTAYGTNACNTCNGARCARATG AARCAYYTNTCNCCNGARATHGARMGNTTYGARGAYYTNGTNGCNYTNGAYGGNGGNTGY GAYGGNTTYGAYYTNGTNAARCAYATHYTNCAYCARGCNGCNTTYYTNGTNATGTCNAGY GGNCAYYTNYTNATGGARGTNGGNGAYCAYCAYCCNGARATGATHAAYAAYTAY---GCN YTNGARAAYAARCARYTNAGYYTNCARTTYATHAAYGGNAARMGNGAYATGTTYGGNAGY AAYMGNTTYTGYCAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GGNACNGGNGTNCCNGARGAYYTNYTNGCNACNYTNAAYAGYYTNCARGARGARYTN AARGCNYTNCARGARGGNCARATGAARGAYGGNGCNGCNATHAARMGNYTNCARGAYGCN YTNCARAARYTNCARAAYGAYATHGARAAYYTNMGNGGNGCNGTNGAYAAYYTNTCNAGY GARAAYTCNGARMGNATHAARGARACNACNGAYYTNAAYCAYTAYTGYGAYAARYTNGAY AARAAYAARGCNGAYAARGARTAYGTNGAYACNGARGTNGAYACNAARGCNGAYMGNMGN CARYTNGCNTCNAARGTNAAYCAYAGYYTNTTYGAYGARACNACNAAYGARYTNAAYMGN ATGATHAARGAYATHYTNGAYAARYTNAAYGGNCAYGARGARGGNTGGAARTCNGCNYTN GCNAARGCNATGGARGARYTNGAYGGNAARYTNGAYMGNATGGARYTNMGNAAYYTNAAR GAYTGGYTNGARAARCARYTNAARGCNATHAAYAAYAARATHAARACNATGGGNCCNGGN TTYCARYTNGAYGAYGARGCNGCNGGNATGAARAARCARYTNATHCARMGNTTYAAYTGY YTNTCNTGYGAYAARCCNGTNGAYGTNATHCCNCARGGNCCNATHCCNTCNATHCCNGGN AAYTAYGGNATGCCNMGNTCNAARTCNCCNMGNCCNTAYACNACNTTYGARYTNGAYCAR ATHMGNCARCAYGCNMGNGAYYTNGGNATGAGYCCNGARYTNGCNGAYTAYTAYGCNCAR GCNMGNCARTGYGGNGGNCAYCAYACNATGACNTAYCCNAAYAARMGNACNACNAARYTN AAYCAYYTNGGNCARATHTCNMGNGARGARGARACNATHYTNCCNYTNTAYAARGAYGAR ATHGAYGTNCARGGNGCNGAYGGNCAYATHTAYAARGGNMGNATGGARTCNGCNMGNYTN GARGCNAARYTNCCNGTNAAYYTNACNGCNCARCAYTCN---CAYCCNGTNTAYATGGAR CCNAARTCNCCNTCNCCNCARCCNCCNAAYMGNCCNATGTCNACNMGNGTNCCNMGNCCN AAYTCNGCNMGNCCNGGNTCNGCNCAYTCNCARCARMGNGCNCARTCNGCNGTNCCNATG ACNMGNGARGAYTCNGTNCCNGTNCCNCARAAYAGYCARATHGGNGGNTCNMGNGCNACN ACNCCNATGCARGARGARGARGTNGCNGCNGTNGAYYTNGTNGCNAAYCARGTNGCNGTN GARAAYCARGTNCCNGARGAYGARMGNGCNGGNCARGARACNATGGTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TGYTCNATHATGMGNGAYTTYGTNATHGGNYTNTGYYTNGCNGTNAGYTCNTCN ATHTTYATHGGNTCNAGYTTYATHYTNAARAARYTNGGNYTNYTNMGNTAYGCNMGNAAR GTNAGYGTNMGNGCNGGNCARGGNGGNYTNGGNTAYYTNMGNGARTGGATGTGGTGGGCN GGNATGATHYTNATGACNGTNGGNGARTTYGCNAAYTTYGCNGCNTAYGCNTTYGCNCCN GCNACNYTNGTNACNCCNYTNGGNGCNYTNAGYGTNATHGTNAGYGCNGTNYTNTCNGCN MGNGTNYTNAAYGARAARYTNAAYATHYTNGGNAARGTNGGNTGYGTNYTNTGYGTNYTN GGNTCNACNYTNATGGTNATHCAYTCNCCNAARGARCARGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNTCN TCNMGNGAYAARATHACNYTNGCNMGNMGNGARAARCARATHYTNTAYGGNAARAGYACN GAYTCNTAYAARATGTAYATHGCNACNGTNCCNGARGAYGAYMGNAGYGTNGAYMGNAAR AARCAYCCNMGNACNCCNACNAARTGGYTNMGNTGYAGYMGNMGNAAYTGGGAYGCNCAR ATHAARGCNTGGAARAARCAYATHCAYAAYTGGGCN------ATGCCNGGNGAYAGYGCN ACNTCNCCNACNAGYGARATHAARCCNYTNATHAARGCNYTNATHACNACNGCNGCNTCN TCNAGYTCNACNTCNGCNACNACNACNGTNTTYTCNGAYGCNTCNAARCCNTTYMGNCCN AARYTNAAYAGYGTNAARATHAARGGNGCNGARTCNGTNTGYCAYGARGTNAAYATGTCN GARATHATHATHCCNCCNCCNATHAARACNGARGAYGTNCCNYTNCCNCCNGGNAGYCCN AARACNACNGCNACNGGNACNAARCCNGAYCAYCARGCNATHACNGARGARCCNACNAAY ATHTCNYTNCCNGGNAAYCCNCCNACNTCNGAYGAYAARAGYACNAARGARACNATGGAR YTNGGNAARGGNAGYGTNTCNTTYTCNTTYAAYAARACNACNAGYAARATHGCNACNACN TCNGCNTTYAAYCARGARGARCCNGAYTCNATHGARGTNCCNCCNACNMGNCCNYTNACN YTNATGGAYAGYATHGARGARGARAARMGNYTNATGAAYGAYGCNTCNCARGAYGGNYTN GAYGCNACNAAYGARAGYAARCCN------------------------------------ ------------------GCNGCNGCNACNAARCCNMGNYTNYTNGARGAYTTYGTNCAR GTNTCNYTNYTNAARGARGGNGCNGGNGARATHCARTGGCCNGCNGARACNATHAARTAY ACNAAYACNCARCCNAGYATHCAYTAYTCNTGYAAYCCNATGCARTTYGAYTTYAARGAY ATHATGAARATHGGNGGNGGNGGNGGNGGNGGNGGNGAYGCNAARAARGARGGNGCNGGN GGNTCNACNAARGARGARGARAARGTNGAR------AARGARACNAARGAYGGNAARGAY AARAARAARCAYTCNTCNMGNAARAARMGNAARMGNAARAARAGYGGNGGNAARGGNGGN GAYGGNGARAARGARGGNAARGARGGNGARACNGAY---AARGARAAYACNGTNGGNGAR GGNGARGARAGYAAYAARAARGARMGNAARAARAARMGNAARAARMGNAARAARGGNAAR CAYMGNCAYAARAGYAARAARGAYGGNGARGARGCNGGNGAYAARGCNGTNAGYAAYAAR GARGGNAAYGGNGGNGAYAARAAYGARGARAAR------TCNMGNMGNMGNTCNCAYMGN AARMGNACNCAYAARGARMGNGAYGGNGCNTCNGARGTNGARAGYAARGARGGNGARAAY GARGGNGTNYTNAAYGGNAARAARMGNGCNTCN---------TCNCARAARTAYAGYAAR CAYAARCAYAARMGNAARCAYMGNMGNMGNMGNCAYGAYMGNTCNGARAARGCNAARGCN ATGAGYGCNTCNGARAARGCNAARGTNGARAARAAYGTNGARATGGTNAAYGCNAARGAR CCNAARGTNAARATHGAYTAYGAYGARGARGARGARACNCAYATHCCNTCNGAYAAYGAR CARGAY---ACNYTNGARCCNAARATHAARMGNCCNTGYMGNTCNMGNAARMGNCAYAAY MGNAAYAGYGGNCAYAARGARACNCCNGARGARAAYGTNATHAARACNGARGAYCARGGN ATGGAYCARYTNAAYATHACNTTYAARACNCAYAARAAR------ATGCARGARAAYGTN GCN------AGYYTNCCNGARATGACNAARGGNGGNYTNAAYAARYTNACNGTNCCNACN AARGARAAYGARTCNCARCARAAYAARACNCCNAAYGGNGAYATHAGY---GGNMGNAAR MGNGGNACNAGYATHTCNAGYGCNGAYGGNACNACNCCNGCNAARGTNAGYAARGTNGAR AARGTNTCNACNACNGARGAYACNTGGAGYAARATGGARGGNYTNTAYGARGCNAARGGN GARGARGGNTCNAARAGYAARTGGGAYACNAGYGAYAGYGARGGNGARGAYGCNYTNCAR AARACNYTNGAYGCNAAYGCNAAYGARGARAAYGTNAARGGNGAYGGNAAYCAYCAYAAR YTNAARCARAARCCNACNAAYGGNAARATHCCNYTNGCNAARTCNYTNYTNYTNACNAAY ---------------------------------GGNATGAAYCARATHAARYTNCAYACN YTNCCNACNAAYGAYAAYCCNATGAARCAYAAYAGYACNAARAGYGAYAARGGNGAY--- GARGGNAGYGAYCCNAARGAYAARTCNAGYTCNAAYAARCARTCNCARMGNGARGGNMGN TCNAARAAYMGNAGYACNMGNMGNTCNTAYACNTCNTCNGARTAYTCNTCNCAYTCNMGN TCNTAYTCNMGNTCNMGNTCNGGNTCNTAYMGNAGYTAYTCNGAYGAYTCNMGNTAYTCN GAYTCNAGYMGNTCNCAYAGYMGNTCNTCNMGNAGYTAYAGYMGNAGYMGNTCNMGNCAY MGNTAYMGNMGNMGNTCNTCNTCNAGYMGNGGNMGNAGYMGNAGYTAYAGYTAYAGYAGY MGNAGYAGYTCNGGNMGNTTYMGNTCNMGNTCNTAYTCNMGNTCNMGNAGYTAYACNMGN TCNMGNTCNMGNAAYMGNAAYTAYCAYAGYTCN---TCNMGNAGYCCN---TCNMGNMGN AGYACNAARYTNAARMGNATHYTNAARTCNCCNYTNGCNATHGTNCCNGTNACNACNYTN ACNGTNGCNCCNGTNACNGGNTGYACN--------------------------------- ------AGYGGNGGN---GGNGCNGGNGGNGCNCCNCCNAAYGAYATHCCNYTNCCNGGN AARGAYGCNCCNTCNGCNGCNGCNTCNACNAAYGTNACNAGYCCNAARAARGARGARGCN GTNYTNATHGAYATHCCNYTNCCNACNACNTCNGGNAARCCNACNYTNGAYGGNAARGAR AAYTCNAAYTCNGGNGARACNAGYYTNACNGCNGGNGGNGAYCCNGCNAAYATHCCNAAY CCNATHGTNAARCCNTCNGAYCCNGCNTCNACNAAYCAY---AAYCCNGCNAAYGGNAAY AAYACNGAYTCNYTNGGNAAYCCNGTNGARAAYAGYAAYYTNCCNCCN------------ ---------------------GAYGARATGAGYGGNATGGTNAAYCCNAAYGAYATGYTN GGNTAYGAYCARGARTCNTTYCAYCARATGGGNAAYAAYCAYCAYGAYCCNTCNTTYTGY GARGAYACNGGNTAYGAYAAYTTYGARTTYGAYGGNGCNTCNGAYTAYGAYCAR------ ---CARGGNGGNTAYGAYGARCARGARTAYGARTAYAAYCCNGAYCCNTAYCAYCAYCCN CCNYTNMGNCAYCARGGNCCNCAYCAYGGNCAYGGNCCNMGNGGNCCNCCNCCNCAYGGN TAYMGNGGNCCNCAYCCNMGNATGTTYCAYCCNGAYATGMGNTTYGGNCCNCCNMGNCCN GGNATGGGNCCNCCNMGNATGMGNCCNAGY---GGNCCNATGGGNCCNCAYCCNCCNATG GGNCCNMGNGGNCCNMGNCCNCCNATGGGNCCNGGNGGNCCNATGGGNCCNCCNGGNATG MGNGGN---CCNCCNMGNGGN---CCNCCNMGNTGYCCNCCNGGNATGMGNGGNCCNCCN GGNATGCCNGGNYTNMGNGGN---CCNCCNMGNCCNGGNATGATGGGNCCNCCNCAR--- GGNCCNATGGGNCCNAAYGGNCCNMGNCCNMGNATGGGNCCNCCNCCNCCNMGNATGGGN CCNCCN---CCNGGNCARGGNCARGGNCCNATGCCNCCN---CCNGGNGGNCCNMGNAAY MGNATGCCNCCNCCNGGNCAYATGTCNGGNCCNCCNATGMGNGARGGNCAYCCNCCNCCN CARMGNCCNGGNATGCCNCCNCARGTNMGNGGNCCNATGCCNCCNCAYATGMGNGGNCCN ATGCCNCCNCAYYTNACNCAYCCNCCNCCNAAYTTYAAYATGCCNCCNCCNTCNTCNGGN GCNGGNGTNGTN---------------------AARCCNCCNGAYTCNATGGARCCNCCN CCNYTNCCNCCNCCNAARGCNCCNACNCCNCARCCNCCNCCNCCNCCNAARAARGARGAR GARAARAARGARGARATHAARCCNATGGTNCCNGAYATHCCNCCNGARCARGCNGARCAR TAYMGNAARYTNMGNGARAARGCNCARAARCAYGCNAARAARCARYTNMGNAARCARGAR CAYCARGCNAARGGNGARCCNGARAGYAGY------GAYGAYGAYGARGARACNGCNAAR AARAARGARGAYGCNGCNAARYTNGCNGCNGARCARAARGARATGGARGARGCNGCNYTN YTNGCNGCNCARTGYCCNGAYAARGTNGCNGTNGARGARGGNGGNGCNATHYTNGTNCCN ACNTCNCCNACNCCNYTN---GTNCARCARCARGCNGTNTAYATHCARCARCAR------ ------CCNATGGCNGCNGCNCCNTCNGCNTAYAGYATHGTNTCNACNCCNCAYYTNGTN CAYGGNGGNCAYCCNGCNYTNCARGCNGTNGCNGCNTCNTCNGCNGGNCAYCAYGCNCAY CCNCAYGCNYTNGCNCARCCNCARYTNGTNCARYTNCCNAAYGGNCARGTNGCNTAYGCN ACNCCNGCNAARCCNCARTCNGTNCCNYTNCARGCNGGNGCNCCNGTNATHGCNATGGGN CCNCARGCNATGGCNGCNGCNTCNCARGCNGGNATHCCNCAYCARYTNYTNYTNTCNTCN GGNGGNGTNCCNGGNCAYGTNCARGTNTCNCAYGCNATGCCNGGNGCNCARTAYGTNTCN CAYGTNATGGCNGCNCARGCNCARGCNCARGCNCARGCNCAYGCNCARGCNCARGCNCAY ATHCARGCNGCNCARGCNCARGCN------------CARGCNCARGCNCARGCNCARGCN CARGCNCARGCNCARGCNCARGCNGCNCAYYTNCAYGGNYTNCAYGCNATHCCNGCNGGN GTNCAYCCNYTNGCNCARCARGTNATHCCN---GGNCARCCNYTNCARCARCARGGNCAR ATHATHYTNGTNCCNMGNATHGCNMGNCCNCAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATGGGNATHGTNGAYYTNTGGGAYATHYTNGAYCCN GTNAARCARGCNGGNAGYYTNGCNGAYTTYMGNGGNAARAARYTNGCNGTNGAYYTNAGY ACNTGGYTNGTNCARTGYAARACNACN------CCNTTYTCNAAYMGNGCNATHTTYTCN MGNATHYTNGAYYTNATGTCNTAYGGNATHACNCCNGTNTTYGTNYTNGAYAGYATHGAR GCNCCNGTNYTNAARTTYMGNAARMGNGGNATHYTNTTYTCNAAYYTNAAYTCNAARTGG GARGARYTNYTNAARGCNATGGGNTTYCARGTNATHTGGGCNAGYGGNGARGCNGARAAR ACNTGYGCNCARYTNAAYTGYTCNGGNACNGTNGAYGGNTGYATHACNAAYGAYGGNGAY GTNTTYGCNTAYGGNGCNACNGTNGTNYTNAARGAYTAYAGYGCNAAYAGYAARAARNNN NNNACNATHCAYATHTAYGARATGGCNAAYATHGARGARGARYTNAGYYTNGGNMGNAAR GARATGATHGCNGCNGCNGTNYTNATHGGNTGYGAYTAYTGYTCNGGNGTNGARGGNGTN GGNAARAARACNTTYYTNGAYYTNATHAARGARATGAARGCNAAYAAYATHAAYGAYATH YTNGAYMGNYTNACNTCNTGGCARACNAAYAGYCARYTNAARTCNATHYTNGARGARAAR TTYATHYTNACNAGYTGYAARAARGGNAARCAYTGYTCNMGNTGYTCNCAYYTNGGNTCN ATHGAYAARCAYGARAARGAYGGNTGYCCNAARTGYTGYAARACNAARAAYTGYAAR--- ------GARTGGAARAGYGAR------MGNAAYATGGTNCCNTGYTCNTGYGARTTYCAY GTNYTNGARAAYAARGTNAARCCNTTYTTYAARGARYTNAARGTNTAYGARTCNGCNYTN AAYAARCCNAARTTYAAYGAY------GTNATHGCNGARTTYYTNAGYCCNGARAARATH GAYYTNAARCCNGAYGAYATHATHATGAARGARCCNGAYTTYACNCARGTNAGYGTNYTN TCNAARAAYTCNTTYGGNYTNAAYTCNATGGAYTTYMGNMGNTTYTTYCCNGCNGTNATH AARATGTGGYTNTAYGGNCARGGNCCNGAYYTNGGNATHGARCCNYTNGARGTNYTNAAR ACNTGYAARMGNAAYGGNGARACNTGYTAYYTNGTNAARTTYAARAARTTYGARTTYCAY AGYACNGAYGAYGARAAYGGNTAYGARYTNGARGTNYTNAARACNGCNTTYGAYTCNAAR TTYCCNATHTAYATHAARYTNGARGGNAAYTTYTTYATHATGGAYTCNGARCARYTNGTN TCNAAYCCNTTYCARGARYTNCARCARGARGCNGTNAAYGARGCNAGYAARAARAAYAGY ATGACNGARAARYTNACNAGYGTNAARAAYAAYGTNTGYGARAAYCAYTAYCARATGGCN AARAGYTCNYTNGARMGNCARMGNACNAGYAARYTNAARCARYTNCAYGAYCAYGCNAAY MGNYTNMGNCAYGARGTNAARYTNYTNGAYYTNGAYMGNCARMGNCAYACNGTNGARGTN AARAARMGNYTNGARCCNGAYAARGAYTAYAGYTAYGAYGAYGTNCARATHCAYAAYACN GARAARMGNYTNGGNGCNAAYATHGCNTCNTTYTAYYTNGAYAARAARYTNAARTAYCCN ATGMGNYTNMGNTCNATGAARGAYATHMGNGTNACNCCNACNATHTCNAARGCNMGNGCN AARATHMGNACNAGYGAYGTNAAYAARACNYTNGARGARGARACNAGYTTYTCNMGNCAR GARMGNGCNCARACNGCNAARAAYTCNTCNACNGCNCARACNGGNTCNATHAAYACNGCN MGNMGNMGNGGNTCNMGNTCNGCNCCNATHYTNAAYAGYTGYAGYAARACNYTNTTYCCN GCNATHGCNTCNAAYAAYAAYAARGARGGNAGYGTNGCNGGNAGYGARAARGAYGCNCAY CARCAYCARGTNAARTTYGCNTTYGARAAYCCNYTNAARATHYTNGCNTCNAAYGARGAR AGYGCNAAYATGTTYGCNMGNTCNTGYTCNTAYTAYCCNGGNTCNACNMGNGCNATGGAY GCNAGYAARATHTCNMGNYTNMGNGARGARCARCARAARGCNATHYTNGARACNCARGAR CARYTNMGNCARYTNGARAAYTAYAARTCNGAYTAYCARACNYTNCARAARMGNYTNGAR ACNYTNCCNGAYAARYTNTCNCAYGAYGTNATGGTNCCNTTYGGNAARYTNGCNTAYATG CCNGGNMGNYTNGTNCAYACNAAYGARATHYTNGTNYTNYTNGGNGAYAAYTGGTTYGTN GARMGNTCNGCNAARCARGCNTGYGAYATHGCNAGYMGNMGNATGACNGARYTNGAYAAR MGNATHAARGARYTNAARGAYCARCARAARYTNYTNGARCCNMGNYTNGGNATHACNTCN GARYTNCARGTNGCNGCNGARGGNAARGGNGAYTAYMGNGARATHATHGARGARTAYGAY GARGARAARGARATHATHTGGGAYGARCARCAYAARGTNAAYGTNMGNMGNCAYCAYGAR AARATGMGN---AARYTNAARAGYTCNTCNAARACNAAYATGAARAGYGGNGCNGARAGY ACNAARACNAGYGAYGAYGAYATHTGGTCNMGNYTNGAYGCNYTNGARAARCARGARGAY GARMGNGGNGARYTNAAYAGY---------------TCNTGYGARTCNGAYAAYGAYTCN GTNGARGAYMGNGGNCARCCNGAYAAY---------ACNGGNTCNAARMGNCARAAYAAR GTNTAYACNTCNGTNAAYTGGATGGAYGARGARATHAAYGARAGYGAYGGNGAYACNGAR GARGAYGAYTAYGAYAAYGAYGAYGARGARGARGAYGARAGYGAY--------------- ---GARAGYAAYAGYMGNCCNGTNGTNAARACNATHACNTTYAGYCAYACNAARACNCCN GCNYTNCCNCCNGCNGCNTCNAGYGAYGCNACNAARATHACNAGYCCNGGNGARATHTAY AARYTNTTYTCNCCNAARCCNATHYTNAARAAR---AAYTGYTCNAAYYTNAAYTTYTAY GTNGTNCCNCARCAYYTNAAYACNAAYATHGAYGGNYTNGAYYTNTCNMGNAAYTAYATH GARACNYTNGAYGGNAAYACNTTYCARAAYTAYCCNAARYTNAARTAYYTNTCNYTNCAR CAYAAYTTYGTNGAYCAYYTNTGYGTNGAYTCNTTYMGNGGNYTNAAYCARYTNGTNGCN YTNGAYYTNMGNAAYAAYATHYTNTCNATGACNAAYGGNACNTAYCCNGTNGGNGTNTTY AGYCAYATGCAYTCNYTNGTNGCNYTNMGNATHAAYMGNAAYATHAARCARATGGAYGAY CCNGAYYTNYTNTAYCCNGAYACNGCNYTNGCNGAYYTNAARTCNYTNMGNYTNYTNTCN ATGGAYGGNATHAARAAYAARACNTTYGGNAARGGNTTYGARACNYTNAARCAYYTNGAR ACNYTNATHYTNAGYGGNTTYAARGAYGGNAAYTGYAAYATHGCNGCNYTNTCNAAYAAY ACNTTYCARTAYYTNACNCARYTNAARATGYTNAAYATHAGYGAYTGYCAYGTNGAYGGN MGNAAYACNGARCCNAAYGCNYTNTTYCCNYTNAARAAYYTNCAYACNATHGAYYTNACN TGGAAYGARGAYYTNACNATHMGNAARYTNGCNGARATHATHGGNGTNYTNMGNCAYTCN ---AAYYTNAARGARYTNTTYATHAARMGNGTNGARTGGMGNTTYTCNCCNGGNATHACN ATHYTNCARAAYCAYACNAARMGNYTNCCNMGNAARYTNTCNTGYYTNGTNGCNGGNGGN AAYAGYATHAAYATHYTNGGNCCNYTNGCNYTNTCNTAYYTNCCNTCNTCNYTNMGNTAY GTNGAYTTYTCNGGNAAYMGNYTNGTNTTYGGNAARTAYYTNAARCARGTNTAYYTNYTN AARAAYYTNGARAARYTNAARYTNAAYGGNGCNGARTAYACNTTYMGNATHCCNATGAAY TAYCCNAARGAYACNGGNCARGTNATHGGNAARAARTAYAAYGARCAYYTNAGY------ ------MGNAARGTNTTYCAYGAYAAYYTNATHYTNAAYYTNCCNCCNAAYYTNMGNGTN YTNGARATGMGNAAYGCNGGNYTNTGGTAYTAYYTNACNAARYTNCAYGTNTCNGARAAY AAYTCNYTNGARGARYTNGAYYTNGCNTCNAAYTAYTTYCCNTCNATHAGYGGNCCNTTY AARGGNTTYGARAARYTNAARAARYTNGTNYTNMGNAAYTGYAARATHGARCAYATGAAY ACNGAYTTYTTYMGNTAYTTYCCNAAYYTNGARTAYYTNGAYYTNTAYGGNAAYTAYATH ---GGNATGTAYTCNAGYYTNTTYMGN---CARCCNTTYMGNCAYYTNTCNAGYYTNAAR TTYYTNGAYATHAGYTTYAAYGTNGTNYTNGAYYTNAARAAYGAYACNTTYGTNGGNYTN TAYAAYYTNMGNGARYTNCAYATHGCNAAYAAYTCNATHTAYATGTTYAAYTCNAAYATH ACNAAYATGTCNAARYTNGARATHYTNGAYYTNGARACNACNTCNATHCCNACNYTNCCN GAYACNMGNAARTAYATHGAYTCNMGNAARAAYATHAARYTNTAYGTNTCNGGNTCNCCN YTNGAYTGYACNTGYAGYAAYATHGAYTTYYTNAAYTGGATGACNMGNMGNAAYAAYAAR GCNATHCCNACNGTNTCNTAYATHTGYATHYTNAAYMGNGCNAGYGTNCAYAGYCARTTY ATHTCNCARGTNAARACNATHAAYMGNGARTGYGCNGCNAAYTAYAGYYTNTTYYTNGCN GTNYTNGGNGGNACNYTNTTYYTNYTNGTNYTNATHACNGGNAGYGTNATGTAYMGNTTY MGNTGGMGNYTNMGNTAYYTNAGYAARAGYATHGTNTCNGTNATHYTNGCNATHTGYCAR AAYYTNGCNYTNGCNGCNGCNGGNACNATHGTNCCNTCNGTNYTNGGNTCNGTNTAYYTN YTNGTNTTYYTNATHATHYTNACNYTNTGGGCNTGYTAYAARTCNYTNGGNYTNACNTAY GGNTTYGTNMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNATHACNYTNYTNCCN GCNATHATHATHATHAGYATHGTNATGATHATHTCNTGYATHGGNAAYACNATGGTNTTY TAYGTNTAYYTNAARAARTTYAAYGCNAGYTCNACNMGNTCNGCNATHYTNGCNYTNGCN YTNYTNGAYYTNATHGCNGGNTGYATHGCNATGCCNGGNGARATHATHGAYATHMGNTTY TCNTTYAAYTTYAARAGYGARATHACNTGYAARTGYATHMGNTTYGGNACNACNGCNGTN YTNATHGCNTCNGGNTTYACNYTNYTNGTNGTNGCNATHGAYMGNTAYMGNMGNATHTGY CAYCCNACNAAYGAYCARYTNACNGCNAGYCARGCNAARAARTGGGTNYTNGGNTGYTTY ATHGCNGCNATHGTNTGYTCNGTNCCNGCNGCNATHATHTAYGGNYTNGCNTGGATHGAR GGNGTNCAYGGNYTNGARTGYTCNATHGAYCAYMGNTAYCAYAAYCAYATHYTNCCNYTN ATHTAYAAYATHATHCARTGYTCNATHTTYGGNTCNGTNGTNATHGCNATHATHGTNYTN TAYAGYYTNYTNGGNMGNCARGTNYTNCARCARAAYAARTTYCARGCNGAYCAYTCNATH ACNGAYGGNACNMGNGAYGGNGARAAYATHTCNCCNGARCCNTAYTTYAAYCCNATHATH AGYAARGGNTAYCARACNMGNMGNTTYTCNTTYTTYAARAGY------------AAYMGN AARGCNACNAAYGGNGAYGTNMGNACNMGNAARACNACNYTNATGYTNTTYTTYATHTCN ATHTTYTTYGTNGCNAGYTTYYTNCCNCAYYTNATHYTNAARGGNATHCARGCNATHAAY AARGAYTAYCCNMGNAAYTCNTCNACNTCNGAYATHGTNYTNTAYAAYATHTTYGTNMGN TCNTAYTTYTTYAAYAGYATGGCNAAYTGYTTYATHTAYGGNTTYTGYAGYGCNAARTTY MGNAARGARAGYAARACNYTNGGNGARGTNGTNATHGGNTAYCAYGARGAYGAYYTNGAR TTYGTNAARAARYTNGCNGAYAARYTNCARTCNAARGGNYTNAGYGTNTGGTAYAGYCAR CCNGGNGARGAYGARAARAARACNGGNGARGCNATHYTNGGNTGYAARGTNTAYYTNCCN YTNYTNACNGARGTNTCNGCNGTNGAYAARAGYATHCAYGARCARYTNTCNYTNGCNTAY ATHTCNAAYTCNGCNATHTAYCCNYTNGGNYTNATHTGYTTYCAYCARYTNGCNCCNAAR YTNAAYGGNGGNTCNMGNYTNATGYTNGCNAARATHAAYTGGTCNTTYATHYTNAARGAY GAYGAYTTYGARCCNMGNACNGAYACNATHATHGARTGYATHGARAARGAYYTNAAYAAY ATHGAYAARTCNGCNGAYCCNYTNGTNGAYGAYTCNAAYTAYGTNATHACNCAYGGNATH MGNGTNCCNGTNAGYYTNGGNCAYYTNCCNAGYCCNGARAAYGAYGARCCNGARTTYGTN ACNTTYTCNCARGGNGTNGAYYTNAGYTCNATHAGYCARAAYACNTCNTTYTGGGAYMGN CAYTTYGARGGNGARAGYGARGTNGAYTGGATHGTNTTYAARGAYAARTTYYTNCARGAY TAYGGNGCNAARATHATGGARGGNTTYTCNGAYGGNGARGARGAYMGNAARAARYTNTTY ACNAAYYTNATGTTYAARGAYGTNTTYTTYYTNAGYAARATHGTNAARCARGCNGTNTAY GCNMGNTTYTGYGGNAARGTNGARCCNCAYGCNTTYTTYACNAARATGCARGARTAYGTN ATGGCNTAYACNTCNYTNMGNGARGTNYTNAGYATGGAYAGYAGYYTNMGNATHTCNACN ATHCARAAYYTNGGNMGNTAYAARTTYCCNGCNATHGTNTCNGGNYTNTCNGAYATGYTN GARGAYGAYGAYCCNAAYATHMGNGCNGTNGCNGCNATHGCNYTNGCNCAYGCNGGNAAR CAYAAYYTNTTYACNGCNGAYYTNATHATHAARYTNTGYGARGAYGARGAYMGNYTNGTN MGNGARAGYGCNTGYYTNAGYYTNGGNTAYYTNMGNTCNACNMGNGCNGTNACNCAYGTN GTNGAYMGNTGGMGNAAYGAYCCNATHTCN---------------ACN---GTNMGNGTN ACNCARGTNYTNTCNTCNGAR---------------------ATG--------------- ---------GAYGCNYTNATH--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHGAR GAYATHGARAARATGATHGARMGNMGNGARAARGARYTNGAYGARYTNGARMGNAARGGN MGNYTNGTNGARATGTCNGAYGARCARTGGCARGARYTNAARAGYGAYAARAARYTNYTN GARAARCARATHAARAARTAYMGNAGYGARYTNMGNGGNYTNMGNTGGAARAAYTGGAAR AGYATGYTNATHTCNGTNTGYATHTTYGGNGCNTTYTAYATHGTNTAYATHGTNGTNTTY GAYTCNGGNTCN---------TCNGGNMGNAARATGGAYACNTGYGTNCCNAAYCCNCAY YTNATGAAYACNCCNTTYGCNYTNAGYCCNCARTCNTCN---ATHTAYGARCARGARMGN CARAGYGCNTTYTGYGGNGGNTCNAARATHAAYAAYAAYYTNGAYGTNTGYGGNACN--- ---------ATHGARGARAGYTGYYTNYTNGAYGAYAARTAYGARGAYAGYTCNYTNAAR AAYATHYTNACNGARGARYTNYTNAAYTCNATGGCNTCNTCNTCNTCNGGNTCNGGNTTY ACNTCNACNAGYGTNTGGAGYAGYAGYAARYTNAAYYTNGARGARTCNTCNCAYGAYCCN TGYGCNGAYTCN---TCNYTNATHCCNYTNAGYATGGAYTCNGAYTTY---ATHTTYCCN GAYYTNYTNAAYGTNGAYTCNAAYGAYAGYAARTTYTCNYTNCCNAAYTTYGAYTTYGAR AGYATHATGAGYAAYCCNCCNTCNTCNTGYCAYACNCCNACNCCNTCNGARACNAARCCN GAYTTYATGGARCCNTCNACNGAYMGNATHAAYTTYATHCCNMGNAGYAARGARACNGTN TCNTCN------------------------TCNACNGARAGYATHGARCARGAYTAYAAR CARAARAARTTYACNATGAARTCNAAYTTYCCNCCNMGNAARTCNGARCCNCCNGTNGGN ATHGTNGCNCCNGTNAARATHCCNGARGAR------------------------------ ------------------CAYAARMGNTTYGAYCAYCAYCCNGTNAARATGGGNYTNAAR ACNAAYAAYACN------------------------------TCNAAYACNGTNGCNATG GARATGGCNGARYTNCCNCCNCARACNGTNCCNTCNTTYACNATHTCNAARCARAARGAR TTYAAY---CCNGTNAARACNGARCCNYTNTCNCCNGARTTYAAYAARAARGAYTGYYTN AARMGNCCNTCNTTYCARGAYAARTGGGARGARGTNAARCAYTTYATHAAYGGNGAYTCN TCNGCNACNAARAGYAARMGNMGNMGNTGYGAYTCNGGNAGYTCNGGNCAYACNTCNGAR GAYGCNGAYGAYGAYGAYAAYGAYTAYGCNTAYCAYAAYGAYGAYGAYAGYGAYGAY--- ---------GAYYTNGAYGCNGAYYTNGCNCAYATGAARCCNGGNGGNTGYGARTCNYTN ATHGGNGGNGGNAARAARCARAARCARTAYTTYTGGCARTAYAAYGTNCARGCNAARGGN CCNAARGGNACNMGNYTNAARYTNGCNGTNGARTCNCCNGTNGAYCCNCAYATHYTNAAY GGNTTYGARGAYCCNGTNTTYGAYGARGGNAAYACNACNGTNGCNGGNATHMGNCAYGGN GGNAARGCNMGNAARGGNGAYGGNAAYGARGTNACNCCNAAYCCNATHAARYTNTTYCAR ATHGGNCAYCARYTNYTNMGNYTNAAYAARACNATHAAYGCNTGYCARYTNGGNTCNGAY GTNCCNATHGCNAARMGNAAYGARTCNMGNAARAARAARAAYAARYTNGCNTCNMGNGCN TGYMGNYTNAARAARAARGCNCARCAYGARGCNAAYAARATHAARYTNCAYGGNYTNGAR ATGGARCAYGGNCARATHAAYAAYGTNYTNMGNYTNYTNTGGCCNAARYTNMGNGAYAGY GCNAARMGNYTNCARAAY---------GARCAYYTNGTNGAYGARAARCAYGAYCCNGAY GAYAGYYTNACNAARAARYTNACNGARTAYATHTCNTCNAGYYTNAARATHATGGTNGCN GGNAAYACNACNGAYTAYGTNAAYAAYGTNATHATGACNGTNGARAARGGNGAYYTNGAY GGNGGNYTNAAYGTN---AARGCNMGNAARACN--------------------------- ------------------------MGNMGNAGYATH---MGNTCNACNGTNATHAGYGTN AGYGAYGARGGNACNGCNGTNGGNMGNGARYTNGARCCNGCNYTNGCNTAYAARGTNGAR AARGCNCCNYTNTCNGCNAARGCNTCNMGNATHYTNAARGARYTNGTNATHGARAARGTN GAYGGNGARAARAGYTTYTTYGARGTNTCNTTYGAYGARTCNTTYATHAAYYTNCCNGGN TCNAARTCNTGYAAYTCNCARAGYGCNAAYACNCCNCARTCNACNACNACNTCNCCNTTY ACNCCNMGNAARTCNAAYGARGTNACNGTNTCNGGNAGYAGYAGYAGYAGYGGNYTNAAY TCNYTNACNACNCCNACNTCNGCNCAYMGNACNMGNCAYTCNATGYTNTCNTTYGGNTCN GGNTTYAARGARCCNGGNYTNCCNYTNTCNGCNYTNMGNAARGCNGGNTCNYTNMGNMGN AARACNGARTAYACNCCNAARTCNAARACNCCNGARCARATGATHAAYATHYTNAARAAR AGYCCNATGGTNGARATGTCNMGNMGNMGNTCNMGNCAYGTNTCNTCNCCNGCN---CCN CCNAARGAYCARTAYTTYMGNGAYYTNATHCARAAYGARACNGAYMGNYTNACNATHYTN TGYAAYAARTGGAAYGAYGTNGTNACNMGNGARATHGGNYTNCCNGARGAYGTNYTNGGN CARATHMGNTCNACNGTNGGNAARGCNYTNYTNYTNATHGARCARMGNTTYAARCARTTY TCNGGNYTNGTNGAYAAYTAYATHTAYGAYYTNGGNGARAARAARACNACNCCNACNGAY YTNCARGGNTTYTGGGARATGATHTAYTTYCARGTNAARGAYGTNGAYGARATGTTYAAR GARYTNGARGARYTNCARGARTCNAAYTGGCARATGAARAGYAARACNCCNAARGCNGTN GGN------CCNAARAARAARGCNACNAARAGYAARCCNGTNGTNAARGGNGTNAARTCN AAR------------TTYGCNGCNTTYMGNGCNGARYTNCARAARAARAAYGCNGCNCAR GCNGCNGCN------ATGGARGAYYTNAARAARATGAARGTNCCNGARYTNAARCARGCN YTNAARGAYAARGGNYTNTCNACNACNGGNACNAARCCNGAYYTNATHAARMGNYTNGTN GARGCN---GGNGGNTGYGTNGAYAAYAGY---GAYCCNGTNYTNGAYGAR--------- ------GAYGARATHYTNAARGAYGAYTCN---------------------ACNTCNGCN GTNGCNGCNGTNCCNCCNAARCCNGCNAGYACNYTNCCNACNGARAAYCCNGARAAY--- ---------------GCNAGYAAYGGNATHGTNCCNAARTCNGAYTCNAAYGTNCAR--- ------ATGGCNGCNGAYACNACNGTNATHGCNAARCCNACNGARGCNAARAARYTNACN GAYGCNGARMGNYTNAARYTNMGNGCNGARAARTTYGGNGCNTCNTCNGARCARGCNAAR AARGAYYTNMGNGCNCARMGNTTYGGNATHGCNYTNAGYGARAAYAAR---TCNGGNAAY ATHAAYTCNTCNGARCCNGTNGAYYTNGAYAARYTNAARAARMGNGCNGARMGNTTYGGN GTN------------TCNACNAGYTCNGTNTCNGARGAYGARAARAARMGNAARMGNGCN GARMGNTTYGGNACNAGYTCNGCNTCNTCNAAR---------ACNATHAGYYTNAAYTCN ACNGAYAGYGARATHGARGCNAARAARMGNAARMGNGCNGARMGNTTYGGNMGNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TCNGGNTCNTGGYTNGARMGNCAYGTNGTNACNCAYAGY GGNCAYMGNCCNTTYMGNTGYATHYTNCCNAARTGYGGNCARMGNTTYCAYTCNCARATG GCNYTNGARMGNCAYGTNAAYGGNCAYTTYGCNTCNGGNACNCCNGGNGTNTCNAARGCN GGNMGNACNMGN------AARGTNAARMGNGCNYTNGTNTTYTGYGAYGCNAARATGGCN GARGTNYTNCAYTGGGTNGGNGGNATGGGNACNYTNYTNGAYGCNGGNGCNGTNGAYGTN MGNGARTTYTCNTCNTTYGARAGYGGNGGNGARGARCARAARAARGGNGTNTTYYTNGTN AGYGGNCCNYTNGARGGNGTNACNGARCARATHYTNCARGAYATHATHATGCARAGYCAY TTYCARTTYGTNGTNGTNYTNACNACNGCNCAYCCNYTNYTNCAYCCNMGNYTNTCNGCN ACNAGYACNGARAGYGGNTCNGCNTTYGARGGNTTYGARGAYYTNYTNYTNGARTGGATG GGNAAYATGAAYTAYACNGCNGARGTNCARCARGTNAAYYTNTTYAGYTGYGARGTNTCN CCNGGNTTYTTYATHACNCCNGCNTTYTCNGARYTNTTYCCNYTNYTNCCNTCNGAYYTN CARCARATHAAYTAYCARYTNGGN---------YTNGCNAARGTNGCNGCNACNTGYACN ACNYTNAAYGAYGTNGAYATGTCNCAYYTNCCNGAYAAYYTNCARATGCARATHMGNYTN TTYTCNACNTCNYTNGAYGGNYTNTTYCARTCNATGAAYATHAARGARGAYATHTAYTCN ATGGGNTGYYTNAGYMGNATHATHGCNACNGAYYTNGAYAGYTTYCCNCCNGCNAARGCN MGNMGNAARGCNTGYCARTCNMGNYTNTCNYTNGTNYTNATHGAYMGNAGYYTNGAYYTN GCNTCNGGNATHACNMGNCARGCNGAYGTNYTNYTNGAYAARATHATHAAYACNYTNCCN CCNYTNGCNGGNCAYGCNACNGAYMGNYTNGTNGAYATGAGYGAYYTNTGYCAYACN--- ---AARTCNACNAGYCARAGYGTNGTNYTNCCNGGNTGYYTNGCNCCNTCNAARATHGCN GAYTCNTCNACNCAYYTNGTNGCNAGYGTNATGAARAARCARAARGARGCNYTNATGGAY ATHAAYMGNMGNYTNGTNGARACNGCNGCNGCNGARAARYTNCCNYTNGAYYTNTCNMGN AARCCNAGYMGNGTNACNGCNGAYYTNYTNGAYTCNACNYTNACNYTNTTYAARGGNAAR TAYTCNYTNATHCAYAARCAYYTNGAYATGYTNCARGTNGCNATGGCNACNAGYCARACN YTNAARCAYMGNTCNGGNCCNCAYCAYGAYAGYGTNGTNGCNMGNGARAARAAYYTNATH CARGCNYTNGCNGAYACNGARAARGGNGARGARGAYGAR---------------GARGAR AGYGTNTAYCCNACNGCNTTYGCNGTNYTNTCNAARYTNATGGTNATGGARATGGAYAAR CCNGARGAYGAYMGNGARTTYACNYTNGAYGAYTTYYTNCAYYTNYTNGTNTAYYTNTAY ACNGTNTCNGAYGGNAGYAGYGARAAYCARGAYGARATHAARCARYTNCARGAYCARYTN GTNCARATGATHATHAARGAYAARAARAAYYTNCCNCCNYTNGTNCARGCNATHGTNGGN GAYAARGTNACNGARTCNATHYTNCCNGAYCARATHGARAGYGTNTGGGARMGNYTNGAY TCNATHATGGARACNMGNMGNGAYYTNAARCAYTTYGGNAAYYTNYTNGAYCCNGGNGGN ACNATGAGYCCNGCNGCNGTNAARCCNYTNYTNMGNCARGTNATGGAYAARATHYTNGAY CCNTCNMGNCCNGARYTNCCNGAYATHGARTGYAARTCNGGNGGNYTNAARGAYYTNYTN AARTCNGGNTTYGGNYTNTTYAARAGYTCNGCNAARCCNMGNCCNGGNGAYGCNCCNYTN YTNATGGTNGTNGTNATHGGNGGNATHACNGGNTCNGARGTNAARCARGTNAARGAYATG GTNTCNAGYGCNAARCCNGGNTTYGARGTNATHGTNGGNGGNACNMGNYTNTGYAGYACN GARTCNACNYTNAARTCNYTNYTNGTNAAYGAYAAYATHAAYATH--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGCARMGNATHTCNAARYTNYTNGARAAYCCNATHTTYCAYTTYAARTCN YTNGCNATHYTNGGNMGNYTNYTNYTNYTNGTNACNGTNGTNTGYYTNTAYMGNTAYTCN TCNTTYYTNGTNAARTTYACNGARYTNGCNGGNGTNCCNGTNYTNAARGARAARTGYCAY TAYCAYCAYGGNYTNYTNGTNTGYYTNCCNATHGARYTNAARGGNGARTCNGTNAARGCN YTNACNATHGARGAYGTNGTNTGYTTYTTYYTNGCNACNTTYCARMGNCCNGTNCAYCAY TTYGCNATGGTNTAYCARCCNTGGAARTGGYTNTTYACNACNATHGARTGYMGNAAYYTN ATGAARGARAARTCNTAYTCNYTNGCNATGCARAARYTNCARTCNGCNYTNAARGARTGY MGNGARCCNCAYCARAARTGYAARYTNYTNTGYYTNTTYGCNGARTGYTAYTTYCAYATG AAYTGYCCNCARYTNGCNATHCARACNTAYMGNGAYGCNYTNCAYGCNGAYAAYAAYTGY TAYTCNATHYTNTAYCARYTNGCNYTNATHTAYCARAGYATGGARGTNCCNGAYYTNGAR YTNGARTCNYTNAAYYTNTGYGTNATGGCNYTNACNGAYGGNAARAARMGNGARAARGAY ---AARGTNCCNGTNATGGARGTNGAYGARYTNGTNTGGTCNGTNATHCCNCCNATHGAR CCNATHACNYTNGTNATGTCNAARGTNACNTTYGCNAARMGNTGYYTNAARYTNAARMGN TAYCARGARGCNGCNGAYCARTAYTCNAGYATHATHCARATGYTNCARCARGAYGARACN YTNYTNGARTTYGARMGNCAYGARACNAARAARCARYTNGAYATHGCNGARYTNYTNGTN GARGCNGCNGARATHYTNYTNATHACNMGNCARTAYCARGARTGYATHMGNYTNTGYAAY AAYACNCARCCNTCNYTNTCNGTNAAYGAYCCNATGGTNAARAAYAGYCAR--------- ------YTNATHAAYGARTCNCARACNGAYAAYGTNTCNACNAAYTCNAAYAGYTCNCAR ---------------TCNGARTTYTTYAAYATGYTNAAYAGYTCNCARAAYGAYYTNAGY YTNAAYCARYTNTCNAGYTCNMGNAARAARYTNAAYYTNYTNACNAGYGGNAAYGAYTCN TCNGCNGAYYTNGCNGTNTCNTTYGARMGN------------TCNMGNMGNAARMGNYTN MGNTCNGGNGAR------------------GTNYTNAAYGGNGARAGYYTNTGYCARACN GAYGAYAAYATHGAYGAYATHYTNATGACNMGNYTNYTNATHTGYAARGCNGAYGCNYTN GTNYTNTCNTCNGGNTTYACNGAYCARGCNGTNAAYTGYYTNCARCARGCNATGGAYACN YTNYTNMGNCAYCCNYTNCARGCNTCNGAYGARGAYCARCCNYTNCARTCNCCNCAYYTN AARMGNCARMGNYTNAAYTCNGAY---------------------------GGNAARGCN TCNGGNAAYGGNGGNGTNCAYTCNTCNGTNTGGTCNAARYTNYTNACNGAYACNGCNYTN MGNATGGCNAARGCNTCNGGNAARMGNAARMGNGTNTCNTCNGTNATHAAYAGYTGYMGN YTNGTNGAYCARYTNGAYAAYGGN------------------ATHTGYYTNAARAAYAAY TGGGCNACNGGNYTNTAYCCNCAYCCNACNGARTGYCAYAARTTYATHGARTGYTCNAAY GGNGAYGCNAGYGARATGACNTGYCCNAGYAARYTNGCNTAYAAYCCNGCNATHATGGAR TGYGAYGGNTCNACNAAYGCNCCNATH---ACNTGGGGNCCN---------AAYGARGAY GTNAAYGARTTYTGYMGNATHACNTAYYTNTTYAAYGGNATHCAYTCNCAYCCNTAYGAY TGYACNAARTTYATHGARTGYTCNTTYYTNMGNACNACNATHATGAGYTGYCCNCCNGGN YTNTTYTAYGAYTCNMGNAAYGARACNTGYGARTCNATHGCNCCNYTNTGYATGGGNGGN ACNGTNTCNCCNACNAAR------------------TCNACNTTYAGYGGNATHTGYGGN TAYCAYMGNYTNACNGTNGGNATHCAYCCNCAYCCNAARTAYTGYGAYAARTTYATHGAR TGYACNGGNGGNAARACNGTNGARATGTCNTGYCARCCNGGNYTNTTYTAYAAYGTNGGN ATHGCNTCNTGYGAYGAYGTNCAYACNGTNGAYTGYAAYGAYAAYTGYGAYGGNAARATH YTNATHGTNGGNGAYGGNGAYTTYTCNTTYACNGTNGCNYTNATGAARCAYTCNGARTTY AAYCCNCAYCARGTNTAYACNTCNAAYYTNGARTCNGARACNTCNATHYTNCAYCAYGTN CARGCNYTNGARAAYACNACNAGYYTNAARGAYCARGGNGTNTTYGTNTTYYTNGARACN GAYGCNMGNGAYYTNCAYAAYCAYCCNGTNATHAGYAARGARMGNTTYGAYMGNATHGTN TTYAAYTTYCCNYTNGCNGAYMGNCAYAAYATHAARAARAAYMGNTCNYTNYTNGCNGAY TTYTTYYTNAGYTGYMGNTCNGTNYTNACNTCNAARGGNMGNGTNYTNGTNACNYTNTGY AARGGNCARGGNGGNACNCCNGCNGAYCARCCNGTNMGNTCNTGGCAYGAYAGYTGGCAR ATHGTNGCNATGGCNACNAAYGCNAGYTTYYTNYTNMGNGARGTNYTNCCNTTYGAYCCN GCNTAYTTYCCNGARTAYCAYAGYGTNGGNTTYMGNTTYCARGAYAARAGYTTYAAYGTN ACNGGNGCNYTNACNCAYGTNTTYGARACNGGNACNYTNATHGARGAYTGYGAYTTYAAY ATGMGNGGNACNGTNCAYTGGGAYGGNATHTCNTAYTCNTGYGCNAAYTAYGTNGCNTCN MGNATHAAYMGNAAYYTNYTNGARGARCCNGGNAAYCCNGTNAAY------------ATH YTNMGNCAR------------GAYYTNTGYCCNTCNGCNAARAGYYTNATHATHGARATG GGNACNMGNGAYGARACNAARAAYTGYTCNGAYAARAARAAYTGYACNAARCARCARYTN GCNCAYGGNGTNGARAAYGGNGTNATGAGYTCNGAYTCNGAYTCNATHGARAAYGCNGTN GGNTCNTCNCCNTGYGAYMGNGARAAYGTNTTYATHYTNGTNAARTCNAARGTNTCNACN ATGATHAAYCARACNTCNAGYGTNAARCARGTNYTNGAYGARAARGARATGGCNAARGGN AAYAAYGARGARAAYAGYGCNTCNATHYTNATGGAYGARGAYGCNTCNACNATHGGNAAY TGYGARGAYGARTCNAGYTTYCAYAAYYTNACNTCNACNCAYATHACNAAYCARCCNGAY GARGARATHTCNYTNCCNAAYATHCCNTCNAGYTCNTTYCCNTGYYTNGTNTCNGGNCAR TGYATGYTNCCNTGYCAYATHATHCCNAAYGCNAGYCCNGCNMGNCAYGARATGYTNGTN YTNCAYCARGGNAGYTTYATHGAYAAYACNCAYCARCCNCARTCNGARTCNTCNGAYATH ATHTCNYTNYTNCAYAAYYTNTGYAAYGAYAAYGCNGTNTCNAARGTNYTNTAYCAR--- ---GTNGAYGTNGARGGNATHCAYACNTCNCARYTNGTNGGNCARATHTTYGTNACNMGN TCNGCNTGYTTYGGNATHGGNGARMGNTTYTAYCAYGTNACNGTNATHGAYYTNCARMGN YTNGTNTGYYTNATGTGYGGNATHGGNGAYTGGMGNYTNYTNTGGTCNACNAGYGARCAY TTYYTNAAYCARTTYCARACNAARGAYTTYCAYAGYCCNTAYMGNCCNTTYAGYYTNTTY CCNATGAARTTYGTNCAYGAYYTNAGYTTYTGGGARAARAAYTCNGGN---TTYATGTTY GAYGTNTTYAGYYTNTAYGARTCNATHMGNAAYGTNGCNGGNGAYYTNGTNGTNAAYGTN TCNYTNATHGAYGTNTAYAARGAYCCNGAYACNAARMGNAARAGYMGNTGYTAYMGNYTN CAYTTYATGTCNTCNGAYAARTGYYTNCCNTAYGTNACNTCNTGGAARYTNCARAGYAAR ATHMGNATGGARGTNGCNMGNAAYYTNGGNGTNCARYTNMGNAARTCNGGNGCNGTNYTN CARGCNCARGGNAAYGAYTTYGAYAARMGNYTNAARAARYTNCCNGARACNGGNYTNGGN CAYGCNYTNYTNGARTCNTCNCARGGNYTNAAYATHGAYACNYTNYTNGGNCAYACNTGY ------------------------------------------------------------ ------------TTYYTNATHCARTAYCARAAYTAYAAYGCNTGYGTNTGGGGNATHGGN TCNGCNATHGCNGCNTTYYTNGCNYTNTGYGTNACNATHGCNTTYATGMGNGGNGTNTGG GAYTCNAAYCCNGARMGNYTNAARGTNTTYATGYTNACNGGNTGYTTYATHCARYTNGCN GGNGTNTGYGGNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------ATGAGYMGNTCNGAYCCN ACNTCNTAYTCNGARCCNGARAARTGYGTNATGAARAARYTNAAYTGGAAYGTNAARYTN GAYTTYAAYGCNCARACNATHAGYGGNGTNGCNMGNYTNTAYTTYGARAARAARTCNGAY GARYTNGAYYTNYTNYTNYTNGAYGTNMGNATHYTNAARATHGARAGYGTNMGNYTNGAR GARAAYAAYCARAAYYTNAGYTTYACNATHGAYAAYCCNTCNGARGTNGAYTTYGGNTCN MGNYTNTGYATHCARYTNCCNATHATHCARAGYAARAGYTTYATHATHGAYATHTCNTAY AGYACNATGCCNGARTCNACNGCNYTNCARTGGATGACNCCNGARCARACNGGNGGNAAR MGNCARCCNTAYYTNTAYAGYCARTCNGARGCNATHCAYGCNMGNAGYYTNTTYCCNTGY CARGAYACNCCNGCNGTNAARTTYACNTAYAARGCNCARGTNGARGCNCCNAARGARATH ACNGTNYTNATGAGYGCNAAYMGNGGNCARGTNACNCCN------GGNTGYGARGGNCAY TGYGTNACNGAYTTYTCNYTNGAYATHCCNATHCCNAGYTAYYTNYTNGCNATHGTNGCN GGNGAYYTNGARTCNMGNACNATHGGNCCNMGNTCNAARGTNTGGTCNGARAARGARTTY GTNGAYYTNGCNGCNTAYGARTTYGCNGARACNGARGCNATGYTNCARGTNGCNGARGAY YTNATGGGNCCNTAYGTNTGGGGNCARTAYGAYYTNYTNGTNYTNCCNCCNTCNTTYCCN TAYGGNGGNATGGARAAYCCNTGYYTNACNTTYGTNACNCCNACNYTNYTNGCNGGNGAY MGNTCNYTNGTNAAYGTNGTNGCNCAYGARATHTCNCAYAGYTGGACNGGNAAYYTNGTN ACNAAYGCNAAYTTYGARCAYTTYTGGYTNAAYGARGGNCAYACNGTNTTYTTYGARMGN AARATHTAYAGYMGNYTNTAYGGNGARCCN---MGNAARCARYTNCAYGCNAAYAGYGGN TGGATGGARYTNAARAARAARATHGAYGARYTNAAYGARGAYGAYCARTCNCCNTAYACN MGNYTNATHCCNGARYTNGTNGGNGTNGAYCCNGAYGARGCNTTYTCNGCNGTNCCNTAY GARAARGGNTAYGCNYTNYTNCARCAYYTNGARACNYTNYTNGGNGGNCCNGAYGTNTTY AAYCCNTTYYTNMGNGCNTAYATHGARCAYTTYAARTTYCARTCNATHYTNACNAARGAY TGGAARGAYTTYYTNTTYGGNTAYTTYACNTCNGCNGARGAYCARGARMGNYTNGGNAGY YTNGAYTGGGAYMGNTGGYTNTAYGGNGARGGNATGCCNCCNTTYGAYCCNMGNTAYGAY YTNAGYYTNGCNGARGCNAGYMGNAAYYTNTGYCARMGNTGGATHGARGGNGGNGARGGN ------GARGCNTTYTCNCCNGAYGAYATHGARGGNATGAGYTGYGAYYTNGTNACNGAY TTYYTNTCNGGNYTNTTYTCNGCNCARCCNCCNATHCCNYTNTCNMGNGTNCARCARYTN GARTCNACNTAYCAYTTYCAYGGNGTNAARAAYGCNGARATHMGNATHAARTGGYTNCAR YTNTGYGTNAARGCNGGNTGGGTNGAYGCNATHCCNCAYGTNYTNAAYTTYYTNAAYGAR CARGGNMGNATGAARTAYGTNYTNCCNYTNTAYMGNGCNATGAGYAARTGGGARGGNGGN AARAGYGCNGCNCARGARAAYTTYTCNGCNCAYMGNGCNTAYATGCAYAGYACNACNGTN AARAARGTNGAR---ATGTCNGTNGAYTTYMGNAGYAGYGARMGNMGNMGNTAYAAYGAY YTNCARGCNMGNGARAARGARATHGCNGCNGTNAARGTNTCNTCNCCNTCNTCNCCNAAR ACNCARCARCARAAYGAYAARMGNGTNMGNMGNGARATHGCNAAYGGNAAYGARMGNMGN MGNATGCARTGYATHAAYGCNGGNTTYACNTCNYTNMGNGCNYTNATHCCNCAYYTNGAR GGNGARAARYTNAGYAARGCNGCNATHYTNCARCARAGYATHGAYTAYATHACNAGYYTN GARAARGAYAARAGYMGNYTNCARATGCARYTNGARMGNACNACNMGNYTNYTNGCNGAR YTNGGNCARCARGAYMGNGTNYTNGTNGAYTCNTAYGTNACNAAYACNCCNCCNCCNACN AARMGNAARAARMGNGAYACNGARTCNTCNGAYGARGGNGTNGGNTCNYTNTCNGAYGCN TCNGAYGAYTGYGGNACNGAYYTNMGNCARAARAAYGARGCNYTNMGNCAYCARATGGAY MGNGARAARCARMGNGGNGAYTCNYTNGARGARGARAAYMGNAGYYTNMGNAAYYTNATG TAYYTNATHCARAARCARAGYGCN---GAYCARCAYCCNATHACNGTNGTNACNGCNACN CCNCARGAR---ACNMGNGTNMGNGAYATHYTNGARGTNATGTCNCCNMGNYTNAAYTAY ACNCCNAGYATHACNGCNMGNCCNTCNTCNCCNGAYAGYACNATHACNATGGCNGCNACN GCNGTNCCNTCNATHCAYCCNACNGTNACNGTNGCNTCNTCNGAYGTNCARATGGARYTN MGNTCNGCNGGNAGYATGGCNAGYCCNAGYTCNGCNGAYAAYATHAAYACNTCNAAYAAY CAYAAYTAYGCNCAYMGNGAYCAYCCNMGNMGNMGNCAYCAR---ATGGAYAAYCAYGAR GARATHYTNGAYGCNYTNACNGCNTTYGGNAARAGYCCNAAYCCNCARGARATHCCNTCN GTNYTNGARCARTAYYTNAAYTCNGTNGCNAARAAYGGNGARACNATHTTYCCNTGGTCN CARYTNAARCCNYTNATHYTNMGNAARATGGARYTNGTNATHYTNGARYTNMGNMGNAAY YTNGCNACNGARAAYATHCCNAAYMGNCCNAAYGTNGARAAYGTNMGNTTYGAYGTNATH CAYGCNMGNATHATHGAYTCNYTNCAYAARTTYAAYGGNGCNCCNTTYACNATHCARMGN YTNTGYGARYTNYTNATHGAYCCNAARMGNCAYTAYAARMGNAGYGAYAARTTYATGMGN GGNYTNGARAARAAYGTNYTNGTNGTNAGYACNGTNGAYCCNTTYGGNMGNAARGTNGTN TGYGARACNGGNAAYAARCCNATHYTNAAYGGNATHATG---GAYATHAAYGGNTCN--- TAYCCNCCNMGNGAYACNGCNYTNAGYATHCCNYTNCCNCCNGTNCCNGGNTGGGTNAAY ACN------GCNGCNGCNMGNACNGTNGCNGCNATGCCNTCNGTNGAYGCNAGYAARACN AGYGCNGGNAAYAAYYTNGAYACNATGGGNGAYACNGTNATHGTNTCNAAYAGYGTNTCN AGYGGNATGGCNGCNTCNGCNTCNGTNTTYTCNGAYCARGGNGAY---CCNYTNGCNGTN CARTCNGARGARGTNGTNGARGARACNGTNGTNACNATGGAYACNGGNGARGTNAGYTCN GTNGTNACNGAYGGNGGNGARGCNYTNGCNGARMGNGARGCNGARGGNGAY------ATH GGNGAYGAYMGNGARGCN---TCNTCNTTYTCNTCNTCNTCNTCNTCNTCNGARGARYTN TCNTCNTCNGAYTCNATHGARAAYGGNYTNMGNACNTCNTCNTTYGTNGTNGCNGARGAR GCNACNGTNATGGAYGARAGYMGNCCNTGGGCNGCNTTYGCNGAYATGAARCARCARGAR AAYYTNACNACNTCNCARTCNGTNTCNTCNTCNTCNCARCAYAGYACNTCNCCNGAYGCN TCNTCNTCNYTNCCNTCN---TCNTCNTCNCCNTCNTCNTCNACNACNTCNGARACNCAR TCNGCNACNACNTCNTCNAARTCNGARGARGAYAARGTNCCNAGY------CARCARGAY CCNTCNCCNACNCARCARACNTTYTCNTCNGARYTNTCNAGYTGGCAR------------ ---------------------------------------GCNTGYGAYGAYTCNTCNGCN GCNGCNACNGCNGCNAAY------CARAGYTTYGGNTTYGARCCNGTNGTNAAYTCNGTN TCNCAYAAYGTNACNACNGARACNGTNACNGAYAAR------------------------ ---------------------------------------------------YTNATHTCN TCNTCNACNACNYTNGTNACNACNACNGCNACNACNACNGAYAAYACNTCNGARAAYAAY ATHCAYATHTCNTCNTCN------------------------------------------ GGNAGYATHACNTAYGCNCARGTNGCNGCNTCNTCNACNACNGAYCARTCNTCNTCNYTN CAYCAYYTNTCNCCNTAYGAYTCNGTNGCN---GAYCCNGTNCCNTGYGAYAGYGTNGCN GGNYTNGARMGNYTNGTNGGNTCNATGGARCARTCNTCNTCNTCNTCNCCNCCNTCNACN CCNGTNGTNTGYYTNTCNTCNTCNTCNTCNTCNTCNTCNTCNYTNYTNTCNTCNTCNCAY CCNGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TCNATHYTNMGNGAYATHACNGCNATGAGYTGYGAYGGNCAYACNTGGAGYCARGAY GAYYTNYTNCAYYTNGARAGYGARYTNYTNYTNGCNACNGARGARCCNYTNTGYYTNGAY CCNTCNCCNGCNGTNATGTAYATHAARAAYGCNYTNCARTAYCARGARAARATGYTNAAY GAYCCNGCNYTNAARMGNTCNGTNAARAARCAYACNCARGTNGCNGCNAAYMGNAARMGN AARYTNGCNCARTCNGTNGCNCCNGAYAAYATGMGNYTNCAYGAYTTYGTNATGAARAAR AARGGNAARACNAGYYTNTCNAARACNMGNATGATHGTNGAYTCNTTYAARCARACNTCN GARCCNGCNYTNACNAARCCNGARTCNATHGAYGTNAARAARTAYGCNAARCCNCCNGAR ATHCCNAGYACNMGNGGNATGATHTTYGTNGARGARCAYACNATGGARMGNGAYCCNAAY CARGAYCAYCAYATGATGGCNCARATHACNATHTAYCARCCNCARYTNGGNGAYMGNTAY TAYGGNGARTTYTAYYTNGAYCAYGAYTAYGGNCARAGYMGNTCNGGNAARGARGGNMGN AARTGYMGNTTYGTNATHGGNTCNMGNCARTGYGTNGAYMGNTAYYTNCARCARTTYAAR GAYYTNTTYACNGARGARGGNAARYTNCARATGAARATHACNATHMGNAARGCNAAYGAR CCNACNCCNACNATHACNTAYACNCARGGNYTNCCNAAYGCNGTNTCNCCNGTNACNGCN GTNCCNACNACNATHGCNATHAAYACNGCNCARGCNGCNYTNATGAARCARGTNGCNTTY AAYCARCARGCNGTNAARGCNGARATHGGNGCNCCNGTNGCNGGNYTNGCNAAYAARMGN AAYTTYCCNATHCARYTNTCNYTNTCNYTNAGYCCNGCNGCNAAYGCNTCNGCNGGNATH CCNTCNACNYTNTCNACNCARTTYYTNGCNGCNTCNATHTCNACNTCNATGGTNGCNAAY CARMGNYTNAARACNCCNGGNGCNAGYCARCAYMGNTCNAGYTCNTCNCCNYTNTCNAGY CCNGTNGCNCCNCCNAARGCNTCNACNCCNCARCARGGNACNAGYATHCCNYTNATHGCN YTNCCNAARGCNTCNACNCCNACNYTNACNCCNCCNCCNAAYTCNMGNACNCCNACNCCN ACNYTNGCNGGNTCNMGNMGNCCNTCNAAYGAYYTNACNCARCARATHACN------AGY AAYCARCARACNYTNCARCARCARCARAAYYTNACNAAYTTYATHCARGGNYTNACNTCN AGYGCNGTNGTNTCNGGNAGYGAYAAYCARCARCARTCNCARCARGGNAGYAGYAGYGGN YTNACNAAYYTNAGYATHAGYAAYYTNGGNCARYTNTCNTCNAAYYTNAAYYTNCARGGN YTNGCNGGNYTNTCNGGNGTNAAYATHGCNAAYYTNAGYGGNYTNCARCARATGCARGTN TCNYTNGCNCARATHGCNGTNCCNATHACNATGATHAAYGCNAAYGCNAAYYTNYTNCAR GCNCARCCNGGNATHYTNGCNAAYAGYTCNGCNTCNACNGGNAGYTCNACNGCNACNYTN GTNACNATGGTNACNGCNYTNCCNGCNTCNTCNACNAAYACNACNACNACNACNACNGTN ACNGGNTCNTCNCARGTNGCNGTNTCNACNGGNTCNAAYATGYTNTCNTTYCCNGTNGGN YTNAGYGGNYTNACNCARYTNATGCCNGTNACNTCNAARGGNCARGCNGGNCARGCNATH MGNCCNACNGCNATGCCNYTNYTNCARYTNCARGGNCARCARGGNATHCARYTNYTNAGY YTNCARCARMGNGGNCARGTNAARCARGGNACNAGYAGYTCNAAYACNGCNCARGGNATH ACNMGNYTNCARGCNGGNGGNACNACNACNGTNCCNYTNTCNACNGTNYTNGCNGGNCAR CARATGACNGCNYTNGGNATGGGNAGYAARCCNGGNCARGGNGGNAGYACNGCNATHACN GCNCARCARYTNATHCARYTNACNGGNGGNCARGGNACNTCNYTNGGNCARGGNGCNGCN CARMGNGCNGCNCAYATHACNTTYGGNAARGCNCARCARGGNYTNCARTTYCAYCCNYTN CARYTNAARCARGGNGGNGCNACNYTNTAYMGNTTYTAYCAYTGGAAYYTNATHGAYACN TTYGTNTAYTTYAGYCAYMGNTTYGTNACNATHCCNCCNYTNGGNTGGATHMGNGCNGCN CAYMGNAAYGGNGTNCARATHYTNGGNACNGTNATHACNGARTGGGAYMGNGGNGCNAAR ATHTGYCARGARYTNYTNGCNTCNAARGARACNATHGAYGTNGTNGCNGCNAARYTNGCN GAYATHGCNTTYGTNYTNGGNTTYGAYGGNTGGYTNATHAAYATHGARAAYGTNATHCAR TGYCAYAGYMGNYTNGARGAYGCNAARGTNYTNTGGTAYGAYAGYGTNACNCAYGCNGGN TCNYTNGAYTGGCARAAYGARYTNAAYGAYAARAAYGARYTNTTYTTYTCNCARTGYGAY GGNATHTTYYTNAAYTAYGCNATHACNGARGAYAARYTNGCNAAYTCNAARAARATGGCN CARACNGTNAAYMGNTGYTTYGAYGTNTAYGTNGGNGTNGAYGTNTTYGGNMGNGCNACN CCNGGNGGNGGNGGNTTYAAYTGYAARCARGTNYTNGARYTNATHTCNMGNCAYGGNYTN TCNTGYGCNYTNTTYGCNCARGGNTGGGTNTAYGARAARCAYGGNGCNGARYTNTTYGAY GCNAAYGARATGAARTTYTGGAARYTNATHAARGAYTTYYTNCCNCARMGNATHCAYGCN ATHCCNTTYGARACNTCNTTYTGYCARGGNTCNGGNCARAARCAYTAYYTNGAYGGNAAR GTNATHAGYGAYAGYCCNTGGCAYAAYYTNTCNYTNCARCARYTNCARCCNTGYTAYTCN ------AGYCCNAGYCCNTCNMGNGARAGYATHGCNAGYAAYYTNGARGARGAYGCNGAY YTNGGNGAYCAYTCNGAYAARCARGAYCCNAGYCCNAARTCNAGYMGNGARAAYACNCCN GARAARMGNTCNTCNGAYMGNGARCAYTCNTCNGAYMGNGARAARACNCCNGAYGARGGN CARTCNTCNTCNGTNTCNTCNGARTCNCCNGAYGARCCNCARCCNTCNACNTCNGCNTCN TCNTCNAARGAYGCNCCNTCNACNTCNGCNTCN---TCNGGNTCNCARAARMGNAARAGY ACNYTNACNGAYGARGARYTNAARCARGCNATHAARMGNYTNAARAARCARGAYGARGAR MGNATGAARATGCARGTNYTNGTNTCNAAYTTYTCNGARGARCARYTNAAYMGNTAYGAR ATGTAYMGNMGNGCNACNTTYCCNMGNGCNTCNATHAARMGNYTNATGCARAAYATHACN GGNGCNACNGTNTCNCARAAYGTNGTNATHGCNATGTCNGGNATHGCNAARGTNTTYGTN GGNGARGTNYTNGARACNGCNYTNGAYGTNAGYGARAARTGGGGNGAYTCNGGNCCNYTN CAYCCNAARCAYYTNMGNGARGCNGTNMGNATHYTNAAYTCNAARGGNATGATGCCNTCN ACNAARAGYAARAARACNYTNTTYAGYAAR---ATGTCNMGNAAYAAYGTNCARGTNCCN AGYTCNAAYAARYTNGGNCCNGTNCCNGCNYTNATHACNGGNGAYCCNGCNACNATGTCN ATGGGNYTNATHGTNYTNCARGARTGGTGGGGNATGAAYGARCARATHCARACNTGYGGN AARGARYTNAGYAAYCARGGNAAR---ATGGTNACNYTNGTNCCNGAYYTNTAYMGNGGN AARGTNACNACNGAYAAYGARGARGCNGGNCAYATHATGGGNAAYYTNGAYTGGAARGGN GCNGTNGAYGAYATHCARGCNGGNGCNMGNTAYYTNAARAGYAARGGNGTNAARAARGTN GGNGTNATHGGNTTYTGYATGGGNGGNGCNYTNAGYATGGCNGCNGCNGCNYTNGTNCCN GARGTNGAYGCNTCNGTNCCNTTYTAYGGNATHCCNTCNCCNGARYTNTGYGAYGTNACN ACNATHAARGTNCCNYTNCARTGYCAYTTYGCNYTNAARGAYGCNACNGCNGGNTTYGCN TCNCCNGCNGARTGGAARCCNYTNAARACNAARYTNCARGARAARYTNGCNAARYTNGAR TTYTTYGARTAYGAYGCNGGNCAYGCNTTYACNAAYAARACNGGNCCNAAYTAYAAYAAR GARCAYTGYGAYYTNGCNTTYTCNMGNATGTTYGARTTYYTNCARAARCAYYTNTCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ACNTCNGGNYTNGGNATHYTNGARCCNATHMGNGGNGGNCCN---AAYCCN TCNGARAARAAYCARCCNCCNGTNACNCCNACNYTNYTNGAYACNAGYAARCCNGARGAR ACN------AARAARGTNYTNGAYATHCCNCCNGTNGAYTTYGAYTGGGGNTCNAGYGGN YTNACNAAYCCNYTNAARGTNTTYAARAAYGARAGYTTYAAYAAYGGNATGTCNTCNYTN GARCCNTTYTCNGAYATGYTNCAYAAYAAYATHGARCCNACNAARGARYTNAGYGAYGAR GCNAARAGYATHYTNTCNAARATHCCNAAYYTNAAYTTYATGMGNTCNAAYGTNYTNATG TTYCCNATHAARATGGCNGAYTGGAAYTCNGTNMGNACNYTNYTNAGYAARGTNTCNACN AGYGAYATHAGYAAYGTNTGYCAYYTNATHGCNGARAGYTTYTGYYTNGAYAARGCNATH AARTCNGAYCARYTNATHTCNTCNTGGTCNATHGARGARTGGTGGGARGTNMGNGGNTCN YTNYTNGARYTNATGAARAARGCNGTNCARCARGARTGGAGYMGNGAYCARATHAAYAAR GARYTNGGNCCNGTNGAYGAYTCNTAYAARAGYGTNATHATGGARACNATHTCNGTNCAY CAYATHCCNYTNAARAAYAARYTNYTNCARAAYACNGCNGCNATHTCNCAYGCNATHYTN TCNGAYTTYGAYTGGAARYTNCARYTNGCNYTNTCNAGYGAYAARATGTCNAGYYTNCAY CARCCNTTYGTNYTNYTNGAYYTNGAYATHMGNCARGCNAAYGGNGAYMGNAARCARGTN ACNYTNGARATGGAYAARGARGARYTNTCNAARYTNATHACNTCNYTNGARGGNTGYAGY AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------GTNGTNATHACNTTYTCNAAYMGNTCNAARGARATHGARTGG ACNCCNTAYTTYACNCARTAYYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNCAYGGNGGNCAYGGNAARCCNYTNGARTTYTCNTCNGAR ATHCAYAAYAARGAYCAYATHYTNGARCAYYTNCARCAYCARATHTCNACNAARCCNAAR GAYCARATGACNGAYCARGARYTNGARTTYCAYTAYTTYAARYTNCAYGAYTAYGAYAAY AAYAAYAARYTNGAYGGNGTNGARATHGGNAARGCNYTNACNCAYTTYCAYNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNGANNNNNNNNNNMGNTTYACN------------ GAYGARATHYTNNNNNNNNNNATHGAYNNNNNNNNNNNNNNNTTYGAYNNNNNNNNNGAY GGNTAYNNNGARTAYNNNGARNNNTCNYTNTCNCARGCNAAYCCNCAY------------ ------------------------------ATGGGNMGNMGNMGNTGYAGYGAYTCNGAY GARCCNTAYMGNTCNTCNMGNAARAARAARAARGARMGNMGNMGNTCNMGNACNMGNTCN TGYAGYTCNAGYGAYTCNAGYMGNTAYTCNAGYTCNMGNAGYAARAAR---GTNAARAAR AGYAARMGNTCNAGYMGNAARTCNTCNATHAGYCCNGAYAARMGNGAYTAYTAYMGNGAR CAYTCNMGNAGYMGNMGNTCNMGNTCNACNGARMGNAARACNTCNMGNMGNACNMGNTCN AARTCNMGNTCNCCNGARGCNMGN---MGNTAYAARTCNMGNTCNCCNGARGAYAARMGN TCNCCNTCNCCNTCNTAYTCNMGNGAYMGNMGNTCNMGNTCNMGNGGNMGNMGNTCNGAR TCNAARGGNTAYAGYMGNMGNTCNMGNTCNAAYTCNMGNAGYMGNMGNMGNTCNMGNTCN AGYTCNMGNAGYCAYMGNATHAARTCNCAYCARCAYMGNMGNTCNMGNTCNAARTCNAGY TCNMGNGGNACNACNGAYMGNTCNMGNCAYGGNACNGARGAYGCNCARGTNYTNACNTCN TCNGARAARGCNGARATHMGNATGMGNAARGCNYTNCARGCNGCNGCNGCNGCNGAYGAR AARYTNMGNAAYATHGGNGGNCARGGNTCNTCNCCNTCNTCNTCNGGNYTNGGNGCNACN TCNCARYTNTCNTCNYTNACNTCNGTNGTNTCNTCNAARGARTTYGCNAAYTCNGTNGCN MGNATHGAYTCNGAYMGNTTYGTNCARTCNTCNTTYAARTCNGGNGGNATHGTNGTNAAR GARGAR---CCNGAYCCN---YTNATGTCNAGYCAYGAYGAYGCNATHTTYGGNTCNYTN TCNTCNYTNGGNTTYACNATHAARCCNGAYYTNGAYACNAARCCNGTNTCNYTNGAYCCN GARTCNATHATGCAYGCNAGYYTNTTYTGYAAYGTNGARGAYAARATGGARMGNTGGATH GAYMGNYTNTCNCARYTNMGNMGNAARAARYTNGARGGNGARATHATG------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CARGAYTAYATGAARAAYATGYTNACNAAYAARGTNAAYTGYGAYCAYYTNAAR ATHGTNCCNGGNGTNTCNAAYGGNGTNGCNTCNATHCARGTNGCNGAYAAYGGNGCNAAY TGYATHGTNATHGTNCCNGGNGCNAAYAGYCAYYTNACNGTNGARGAYGTNAGYAAYGCN GARGAYATGATHAARAARTGYCARGTNYTNATHTGYCARAAYGARATHCCNCARGAYATH TCNGTNGCNGCNGTNAARYTNGCNATHGAYCAYAAYGTNAARGTNATHTAYAAYCCNGCN CCNGCNTCNTCNAGYYTNATGCCNGARYTNTTYTCNYTNCCNGAYTAYTTYTGYCCNAAY GARTCNGARGCNGARATHYTNACNGGNAGYCCNGTNMGNTCNGTNGARGAYGCNATGGAR GCNTGYAAYATHYTNCARAAYACNAARAGYTGYAARTCNGTNATHATHACNYTNGGNGAR AAYGGNGCNGTNTTY--------------------------------------------- ---------------------ATGTCNTTYCCNGGNMGNGCNCCNATGGCNATGCCNGGN GGNATGCCNGGNATGCCNCCNMGNATGATG---ACNCCNGGNTAYGCNTTYACNTCNATG GGNATGACNMGNATGAAYCCNATGATGCCNATGCARATGGGNATGATGACNCCNATGATG CARCCNATGATG---CARCCNCARATGCARATGCARCCNCARCARCARCARATGAARCCN AAYACNAARTTYGTNCCNCARGARATHCCNAARACNGAYTCNAARGGNGARAARCCNCCN GTNACNACNGTNTTYGTNGGNAAYATHAGYGARMGNGCNCCNGAYATGATGATHAARCAR ATGYTNCARMGNTGYGGNAAYGTNYTNAGYTGGAARMGNGTNCARGGNGCNTCNGGNAAR YTNCARGCNTTYGGNTTYTGYGARTAYGARGAYCCNGARGCNACNYTNMGNTGYATHMGN YTNYTNAAYGAYTGGCCNATHTCNAAYAARAAYYTNGTNGTNAARGTNGAYGCNAARACN AARACNYTNYTNGAYGAYTAYMGNAARAARAARCARGCNAGYGARGARGARACNGTNAAR AARGARCCNGARGCNAGY------GARAARAARGARAARACNGARGARAAYGGNGARGAR AARGARAARGARAARACNGARGAYAGYAARGARGAYTCNGARAGYGAYYTNGAYGARAAY ACNCARMGNGARGAYMGNGTNGCNCAYGCNGGNYTNGARGCNATHATGMGNGARTAYGCN TTYGARYTNGCNAARGARCCNACNAARCCNTCNGAYGGNGGNGAYCARGARAARGARAAR CARYTNCCNAARAARGAYAARGAYGTNTAYATGCAYGCNAARGAYACNGGNTTYGAYGAY ATGGAYYTNGARGAYGARAARMGNGARATHATHAAYMGNGARATHAAYAARTTYMGNGAY MGNCAYAARGAYGAYGAYGARGAYAARGARAARGAYAAYMGNGARAARGARMGNAGYYTN GCNMGNGARMGNGAYMGNMGNCARGARGARAARMGNCAYMGNGARMGNYTNGARAARYTN MGNGARCAR------------------------MGNGAYMGNGAYMGNGARMGNCCNCCN GCNMGNGTNTCNMGNTCNAARTCNMGNTCNGTNTCNCCNATHCCNTCNMGNTCNMGNMGN MGNTCNMGNTCN------------MGNGARMGNAGYAGYMGNGAYMGNTCNMGNGARMGN MGNAARGARMGNGARATHGARGARGARGARGARYTNTAYGARMGNMGNAARYTNGARAAR AARYTNMGNGARAARGARGCNGCNTAYCARGARMGNYTNAARAAYTGGGARGGNMGNGAR MGNAARAARACNMGNGARTAYGARAARGARAAYGAYMGNGARGAYGARMGNAARATHGAR GARACNMGNGARGCNMGNMGNYTNAARGARTTYYTNGARGAYTAYGAYGAYYTNMGNGAY GAYCCNAARTTYTAYAARGGNAGYGCNYTNCARMGNMGNCARAARGARMGNGARAARGAR AARGARYTNGAYAAYMGNGAYMGNCARMGNGARAARGARGARTTYGARGARATHAARMGN AARYTNTTYGAYGARGGNCAYCCNGAYGCNGARACNGARGTNGCNMGNATGGARMGNGAR MGNGARGARCAYYTNCARCCNTGYYTNCAYYTNCARGARATHAARCARCCNCCNCARCCN GTNGCNAAYGARGARTCNGAYTCNGAYGAYGARCCN------CCNGGNMGNYTN------ GARGTNMGNCARACNCCNTCNCCNAARCARYTNGARCAYCARTCNTCNMGNAAYYTNGCN AAYAAYACNCAYAAYCAR---CARCARCAYYTNGCN---------CCNGARCARCAYMGN CCNTCNCCNTCNYTNTCNACNTCNCCNATHTCNACNGAYTCNMGNGTN---AGYGCNCCN GGNYTNTGYYTNGAYGARTCNTCNCARTCNTCNYTNCCNACNGTNCCN------------ ---------------------CCNYTNCCNGCNTTYGAR--------------------- GARATGMGNYTNNNNCCNGGNATHAGYCCNGAYTCNTCNAGYYTNCCNGGNGCNACNAAY ATHTCNGAYGGNAARMGNAARAARYTNACNGTNGGNGAYGTNTTYAAYCARGAYGAYGAY GAYAGYAAYGARCCNAARAARMGNAARYTNATHCCNYTNGAYTAYGAYGAYGAYAARTCN ACNCCNACNGARAARAARGGNGCNACNGCNGARGARAARMGNCARAARATHAARCARYTN ATHGARAAYATHCCNACNGCNAARGAYGARYTNTAYGCNTAYACNGTNGAYTGGGAYATH GTNGAYCARGGNYTNATGGAYAARMGNATHAARCCNTGGGTNACNAARAARATHGTNGAR TAYATHGGNGARGARGARCCNACNYTNACNGARTTYATHTGYCARAARGTNATHGCNMGN AGYACNCCNCARAGYATHCARAAYGAYGTNGCNATGATHYTNGAYGARGARGCNGARGTN TTYGTNGTNAARATGTGGMGNYTNYTNGTNTAYGARACNGARGCNAARAARYTNGGNYTN GTNAARYTNATHAARGARGARTAYCARAARCAR---ACNAARCAYTGGCCNAAYTCNGGN AARCAYATHYTNGCNCAYTAYGAYGAYGARACNGTNGTNGTNTAYCARGCNTAYAARCCN AAYATHGCNAAYTTYGCNGTNAARTAYCARAARTTYGGNGGNCCNGAYTTYAGYTTYGAY MGNATGTCNTGGATHAARACNAAYTTYATGTGGATGATGTAYMGNTGYGGNTGGGCNCAR AARCARAAYCARGARMGNATHYTNGCNGTNTGGYTNACNMGNGAYGGNTTYGARAAYATH YTNGCNTCNGCNAARTCNGGNAARMGNGGNGAYGCNGARTCNMGNAARGCNGAY------ GARGTNMGNATHCARTGGGAYCCNGAYCAYGAYCCNCAYGGNGGN---AGYYTNACNMGN MGNGCNATHCARYTNGGNYTNMGNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GARYTNGARMGNGARGARGARGCNTTY TAYGARGCNAARMGNGARGCNGCNYTNATHGCNMGNATGAAYAARGCNAARGARCARGCN GCNAARAARAGYYTNGCNAAYGGNGGNAGYGCNAAYGAYGARGARTGGGARATHGCNGGN GGNGARGAYGAYTTYGARATGTTYYTNGCNAGYGTNAARGCNMGNTCNYTNGCNACNMGN TCNCARGTNAARAAYGGNTCNGGNGAYGGNCAYAGYTCNAGYAGYAGYAAYGCNCARACN AARGGNAGYTCNYTNGAYATGGARTGGGARCAYGARGCNGGNATGTCNCCNAAYAARMGN CCNCARCCNGTNTCNGTNTCNGARGAYAAYTGGTCNAARACNTCNACNGCNAGYCCNYTN CAYTCNAGYGAYYTNGARTGGGAYCCNGAYTTYGTNTCNGCNGAYGAYAAYGARMGNYTN CARYTNYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYGGNMGNGAYATHCCNCCNYTNGARGAYATGACNGAYATHYTNCAR AARGCNGARYTNATHMGNGARCARMGNTTYGGNTCNCARGGNGAYACNCARCARATHACN CARAARAARMGNNNNAARGARAARGCNAARGTNACNAARAARAAYATH------------ ---------------------GGNATHAAYAARTCNTCNGTNACNGARGGNAARGTNGAY AAYCCNGTNAARGARGARAAYAARGAYGGNGARAARGARAARGCNAARCCN--------- ---------AARCCNACNAAYTCNAAYGGNCARGGNATGTTYGGNGGNATGAARAARGGN TTYYTNTTYGGNGGNCCN---------AGYAARCARTCNGCNAARTCNTCNTCNTCNAAY GGNAARCARAGYGARAARYTNGCNAGYAARGARAAYACNCARAARAGYTCNGCNACNAAR ACNTCN---------GTNAARGARGARATGCCNTTYATHACNCCNTCNGGNAARACNGAR CCNGGNYTNGCNTTYGAYGARGTNCARCARGCNATGTCNGARGCNAARGGNYTNYTNAAY AAYCARGARTGGATHACNGAYGAYTTYYTNGAYAARATHGARAARAAYGAYTCNYTNYTN AARMGNTTYAGYGAYCCNCAYTTYATGTCNGCNYTNCARGARTTYCARACNAAYCCNCAR GCNGCNATGGCNAARTAYAARGGNAAYCARGARGTNGARAARTTYYTNATGGARTTYTGY GGNYTNYTNGGNGAYCAYTTYACNAAYYTNGAYGGN------------------------ ---------------AGYAAYAARAAYCCNCARTCNAARACNAARAARGARCARGTNAAR TCNGARCCNACNATHGCNGCNGCNTCNATGYTNAARGCNCARAAYGARCCNAARACNCCN AARATHGTNGARATHGGNGAYGAYAARAARCARAARACNACNAARACNGCNAGYAGYGAY YTNAGYAARATHTCNGAR------------------------------------------ ---------AARYTNAAYACNGTNGCNAAYTCNAAYGTNGAYAGYGARTCNCAYATHMGN YTNCAYGAYCCNCARAGYGGNGCNGAYATGCARAARGTNCCN---------------CAR ACNGAYGAYGARGCNGTNAARGARGTNYTNAAYGAYCCNAARGTNATGGARACNYTNATG GAYCCNAARATHATGACNYTNATHAARACNYTNMGNGARGAYCCNGARAARGCNCARMGN YTNATHGAYAARGCNGAYYTNGAYYTNAARGARAARGTNMGNGTNYTNGTNTCNAARGGN YTNYTNCARTTYCAR------CARAAYAARTCNMGNCCNGCNAAYATHCCNTCNYTNYTN YTNCARGAYCAYGARAAYGARACNYTNTTYGARACNYTNGGNMGNYTNTGYATHACNYTN GCNACNGGNGTNGTNCARYTNTAYYTNGCNGAYAAYAGYGARMGNGCNMGNTGGAAYAAR MGNTGYTGYGGNGTNGCNTGYTTYATHAARGAYAAYTCNAARMGNTCNTTYTTYATHAAR GTNTTYGAYATHAARAARCARCARATGYTNTGGGARCARGARYTNTAYAGYCARTTYGTN TAYAARACNCCNMGNGARTAYTTYCAYACNTTYGARGCNCAYAAYTGYCARGCNGGNYTN AAYTTYGCNGAYGARGAYGARGCNGTNAARTTYAARAARGCNGTNGARGGNAARYTNAAY GARMGNMGNCARAARAARCARGARMGNMGNCAYAARTAYGTNTCNAAYAARCARGGNGTN GARCARGGNCARAGYACNAAYACN------------CCNCARMGNATG---GGNATG--- AAYGCNGCNCCNACNCARACNGTNAAYGTNGAYGTNAAYMGNATGAAYAAY------AAY AAYCARAARAARGARAARGAYAARAARAAR------GAYGGNAARAARAARYTNACNAAR GCNGAYATHGGNACNCCNTCNAAYTTYGTNCAYATHAGYCAYGTNGGNTGGGAYCCNGAY AARGGNTTYGAYATGAAYAAYYTNGARCCNGAYATGCARACNYTNTTYCARTCNGTNGGN ATHAARCCNGAYGAYAARGTNGAYAARGARACNGTNGAYTTYATHTAYGAYTTYGTNGAR CARMGNGGNGGNATGGARGCNTTYAGYAARGARYTN---------MGNAGYAGYAAYACN MGNCCNCCNCCNCCNCCNGCNAGYATHGGNMGNAGYGCNCARCCNCCNCCNCCNCCNTCN MGNTCN---------CCNGGNGGNCCNMGNAGYGGNGGNYTNCCNCCNCCNYTNCCNCCN TCNMGNGGNCCNCCNCCNCCNACNATGMGNGGNGCNGTNCCNCCNCCNCCNCCN------ ------------CCNTCNMGNGCNATGCCNGCNGCNCCNAARGCNCCNGTNTCNTCNYTN CCNCCNCCNCCNCCNCCNCCNTCNTCNCCNCCNCCNCCNCCNATGGGNTCNGCNGCNCCN CCN------------------CCNCCNCCNCCNCCNGGNGGNCCNCCNCCNCCNCCNGCN CCNCCNCCNCCNCCNATGTCNGTNYTNTTYGGNGARCAYMGNYTNYTNACNAARAARGTN TTYGAYGARATHTAYATHCCNGARAARGAYMGNGAYAAYTAYAAYTCNGTNCARGCNAAY GARGTNYTNGAYAAYAARGTNGTNTGYYTNTTYTTYTCNGCNTCNTGGTGYACNCCNTGY CARCAYTTYGTNCCNGCNYTNAARGARGTNTAYGCNGARYTNGTNCAYMGNAAYAAYCCN ATHGARGTNGTNTTYYTNAGYTTYGAYAARACNGARAAYGARATGYTNAAYTAYTAYAAR GARAARCAYGGNGAYTGGCCNGCNGTNAARTTYGGNGAYCCNYTNAARCARGARYTNGCN GARMGNTAYTCNATHAGYGTNATHCCNAARYTNATHGTNATHCARCCNGAYGGNGARGTN ATHAGYAAYAARGGNMGNAARGAYGTNCARGAYMGNGGNGTNGTNTGYATGMGNGCNTGG CAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYGTNGCNGGNATGMGNAARCCNTAYAARGGNAAR CARGAYGTNTTYGAYYTNAARGAYYTNACNTCNATHGARCCNTTYGARCARTTYACNACN TGGTTYAAYGARGCNAARACNACNCCNGGNATHATGGARGCNAAYGCNATGGCNYTNGCN ACNGCNAGYMGNGAYGGNAARCCNTCNGTNMGNATGGTNYTNATGAARGGNYTNAGYAAR GAYGGNATHGAYTTYTAYACNAAYTAYYTNAGYAARAARTCNCARGAYYTNAGYGARAAY CCNCAYTGYAGYYTNATGTTYTAYTGGGARGTNYTNAAYAARTCNGTNMGNATHGARGGN AARGTNGARAARYTNTCNCARGARCAYTCNGARAAYTAYTTYCAYTCNMGNCCNMGNTCN AGYCARATHGGNGCNTGYGTNAGYGARAAR---CARAGYTCNGCNATHCCNTCNMGNGAR GTNYTNGAYAARMGNAARGARTAYYTNGARTCNCARTAYAARGAYGARAGYGTNCCNATH CCNAARCCNGAYTAYTGGGGNGGNTTYMGNGTNATHCCNCARMGNTTYGARTTYTGGCAR GGNCARACNAAYMGNATHCAYGAYMGNATHATHTTYTGGAARCCNGAYGARGGNGARACN ATHGAYTCNTCNGTNACNTTYGARGGNAARGARGGNTGGYTNTAYGARMGNYTNCARCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CCNTTYCARATHATHTCNMGNCAYTTYMGNAGYMGNAARCCNGTNGCNGAY TCNAAYCARATHYTNAAYACNGGNTCNCARGGNGAYTCNTTYTCNGTNYTNAARTCNGCN GCNTTYGTNACNGGNGTNTGYGGNTGYAGYTTYYTNGGNGCNATGGTNTGGAAYTAYGAR AAYGTNMGNAARGTNTAYAARGARATGGCNTCNGGNAAR---------GAYTCNCCNCAY MGNTTYATGCAYGARAARGCNTTYGGNTTYMGNAARCAYATHAAYGCNTTYTGGGTNGGN YTNGAYTCNTCNACNAARYTNACNTTYGGNATHATHGCNGCNAAYGTNGCNGTNTGGGTN YTNTGGAARGTNCCNMGNYTNCARTCNGCNATGATHMGNTAYTTYTCNTCNTCNGCNGCN CAYCCNMGNTCNTCNATGGTNYTNAGYAGYTTYAGYCAYATHAGYYTNGTNCAYYTNTTY ATHAAYATGTAYGTNYTNYTNTCNTTYGCNCCNGTNACNACNMGNGCNTTYGGNTAYGAR CARTTYTCNGCNTTYTAYATHAGYGCNGGNACNYTNTCNGCNTTYGCNAGYATHGTNTGY CARMGNYTNYTNMGNMGNCCNYTNGCNGTNTCNGTNGGNGCNTCNGGNGCNATHATGGGN YTNYTNGGNGTNACNGGNGTNYTNTTYCCNCARACNCARYTNCARGTNGCNTTYATHTCN GARATHTTYCCNCAYTCNTTYTCNGCNGARATHGGNATHAARGCNATHATHYTNTTYGAY YTNYTNGGNYTNTGYYTNGGNTGGMGNGTNYTNGAYCAYGCNGGNCAYYTNGGNGGNATG YTNTTYGGNYTNYTNTAYGCNAARTAYGGNAGYAARYTNACNTGGGGNAARMGNGAYTCN GTNGTNAARATHTGGCAYGAYATHMGNGGNAARCCNAARAGYTCNGARGARYTNGARYTN GARMGNATHGARGCNATGMGNAARGARYTNGCNAARGCNAARAARAGYCAYGARGTNACN TAYAARAAYGCNATHTCNAARGGNAARCCNGTNGCNATGAARTCNTCNCARCCNCCNACN ATGCCNCARGGNTTYCAYTTYMGNTCNGAYCARMGNATHAARGGNACNGCNGARACNGTN GARGARACNTCNYTNAARGAYTTYGCNAAYTCNYTNMGNTCNGCNGCNCCN------AGY ACNGGNTCNTCNCARCCNACNMGNCCNAARCCNTTYAAYYTNACNAARAGYATGTCNAGY YTNAAYACNGGNAARTAYAARCCNATGGCNGARCARGTNATGGCNTAYAARAGYGGNAGY MGN------------------GARATHTCNAGYAAYAARMGNGCNGARTCNCCNGGNYTN ACNATHGCNAARACNCCNACNYTNAGYACNMGNGGNMGNTCNMGNTCNYTNAARCAYYTN ACNMGNGARGARGARGARGARATGGARTTYGARAARCAYAARCARCARCARTTYAARGCN CAYGCNGTNAAYCAYAARATHYTNACNGARCCNCARYTNGGNGTNAARAARGTNCCNACN AARCCNCCNACNACNATHAARGARTTYAAYYTNCAYACNAGYAGYTCNCAYTAYGGNGGN AGYAGYTCNAARCARYTNATHGARGARAARCCNACNGARTTYCAYGCNCAYGCNGTNAAY CCNAARATHYTNGARGGNCCNAGYGGNATHAARCCNGCNGAYMGNMGNCCNYTNACNGTN GCNCARTCNCCNGCNTTYGCNYTNAARAAYMGNYTNMGNCCNCCNGARMGNGTNCCNTCN CCNGARCCNCCNAARGTNTCNGGNMGN------CCNGTNCCNCAYATHGGNGTNCCNTTY AARCCNCARYTNGARCAYAARCAYACNGTNACNAARCCNTTYGCNGTNGARCARCAYAGY AARGARATGYTNAARAARAARGARCARAARATHCARCARGTNYTNGAYGARGARAARAAR GCNMGNGARTTYCAYGCNAAYGARYTNCCNAGYGAYTCNCCNGAYCARYTNCCNCCNMGN AARACNMGNCCNYTNACNGCNGTNGARCCNTTYCAYYTNACNGTNGAYGARMGNGGNAAR AARTAYCARGARGARTGGMGNACNAARCARATGGARGARCARGARGARCARGCNMGNGCN AARGCNCARTTYCAYGCNACNTCNAAYAARGTNGTNTTYAARGARCCNTTYATHCCNGAY AARTCNACNMGNCCNYTNACNGARATGAGYAGYTTYACNYTNAAYACNGAYCARMGNGCN YTNAARMGNGARTAYTTYAAYCARCARYTNAARGCNCAYGARGCNGARATHGAYGCNYTN AARMGNCARMGNGARGARMGNAARGARAARGARGARAARGAYGCNGTNGCNAAYYTNMGN CARGARATGGTNCAYAARGCNACNGGNATHAARAARTAYAARCARATHAAYCCNCARCCN AGYGAYAARCCNYTNACNGTNGCNCARTCNCCNTCNYTNMGNACNMGNYTNMGNACNGCN CAYTAYCARGAY---CAYCAYGGNGGNAARGAYGAYCCNCAYGGNGGNGTNCCNATGGGN ATHCCNAAYMGNTTYTGYGAYGAYGGNAARAAYTTYACNACNATHGAYTGGGAYCCNTCN AAYAGYGAYGARTAYACNTGYCAYGGN------GARMGNGTNYTNAAYYTNYTNMGNAGY ---------AGYTCNGARAAYTGYGARGTNGTNGCNAARMGNCCNATHCAYGTNTGYTAY CCNGARGARATHGARTAYGCNGARGAYYTNCCNACNAGYGGNMGNCAYMGNCCNYTNTGG CCNAARTAYGGNGARTAYCARTAYYTNCCNCCNCARMGNTGGYTNCAYTCNYTNGARCAY GGNGCNATHGTNTTYYTNTAYAAYCCNTGYGCNAGYAARGAYCARATHMGNGARYTNAAR GCNYTNGCNMGNGGNTGYYTNMGNMGNCAYATHATHTCNCCNTCNAARMGNATHCCNATG CCNAAYATGTTYGCNGTNYTNAGYTGGAARTGYAARYTNYTNATGACNCAYYTNGAYATH YTNAARACNGTNAGYTTYATHAARMGNCAYGCNYTNCAYTCNCCNGARAARTCNGTNTAY TCNGAYGGNCARTAYAGYATHMGNYTNATHCARCAYGCNGARYTNGTNTCNGAYAAYCAR GARTCNAARYTNTGYCCNCAR---------------TAYGARCCNTTYGAYYTNAGYAAR AARAGYMGNATHGAYGAYGTNYTNGTNCCNGAYYTNGAYGAYGCNGTNYTNMGNACNGCN MGNATHMGNAARAAYCARGTNTCNAARTGYAARTGYGCNGTNMGNAGYATHGTNGCNAAY TCNGTNAARTAYTAYAGYCAYGTNACNGTNGAYAGYGAR---------------MGNATH AARTGYTCNAARGARAARATHYTNGTNGGNGAYMGNCAYTAYMGNTCNGCNACNGARGCN YTNYTNGCNTAYYTNAARCARTTYGARATHTCNGCNGTNGTNGAYAARAAYMGNGAYTCN YTNYTNGGNAGYCARACNAAYGGNACNAGYGAYGGNGARACNACNACNGAYYTNAAYGGN ATHGGNGTNGAYAAYAARAARGAYGARGTNGARCARYTNYTNACNTCNAARGTNTCNCCN GARYTNAARGARGARGTNACNGAYACNYTNMGNGARATHAARYTNAARAAYYTNYTNAAR AARGCNGTNTCNAARTCNCARAARCCNGGNAARACNGGNYTNCARCARGARGTNGARGCN GCNYTNGCNMGNTCNGCNCARYTNYTNGARAARGTNACNATGGARGAYATHYTNTCNGAY ATHAGYGAYATHAGYYTNCCNACNCARYTNYTNYTNGCNGARGCNGARGGNAGYAGYTCN AAYTCNTCNTCNAARATHTCNGAYATHTGYGARAAYYTNMGNMGNATHMGNAGYMGNTCN GTNCCNCCNGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TCNGTNYTNGTNCARAARYTNGAYGAYGARTCNGCNTTYCCNTAYGCNGGNMGNGAR GGNCARGTNGCNTGYAGYYTNTCNAAYAARGTNTAYGTNTTYGGNGGNGTNGARCARGGN CARGGNGAYGARCCNMGNGARTCNAAYGARYTNYTNGTNTTYGAYYTNGCNTCNCARAAR TGGTCNAARCCNGCNGTNTTYGGNTCNCCNCCNGCNGCNMGNTCNGCNGCNTCNTTYGTN GCNGTNGGNACNAARYTNTAYYTNTTYGGNGGNYTNAGYCAYATHTGYGGNTGGTTYGAY GAYGTNCAYACNTTYGAYACNGCNACNAGYACNTGGTCNATHYTNGAYACNGARGGNACN AARCCNMGNGCNMGNGAYAARYTNCARGCNGTNGCNATHGAYACNAGYATHTAYTAYTTY GGNGGNTTYGGNCCNAARTCNGAYGARGCNGARGTNGAYGAYYTNGCNGGNGAYGAYGAY GAYGAY---GARGAYGARGARGAYATHCCNGARAGYMGNGARCARGAYGGNGCNGARTTY GGNTGGTTYAAYGAYYTNTGGGTNYTNGAYACNYTNACNYTNAARTGGTTYCARCCNATG CARATGAAYYTNGGNGTNCCNACNCARMGNGCNGCNCAYGGNATGTGYGCNGTNGGNMGN AARATHGTNATHNNNNNNNNNNNNGAYGTNGARGAYMGNCARAAYGAYGTNCAYGTNTTY GAYATHGAYACNMGNAARTGGGAYGCNGAYYTNAARTTYAGYGGNCARGCNCCNGCNCCN MGNTCNTTYCAYAGYACNACNACNGTNGGNGAYAARGTNGTNGTNTTYGGNGGNMGNGGN MGNGAYAAYAGYCAYTTYAGYGAYTTYGAYATHYTNGAYYTNGARAARAARGARTGGACN MGNCCNTCNGTNGARGGNTAYCARCCNCCNGCNMGNGGNCARCAYTGYGCNYTNACNGTN GGNGAYACNTTYYTNGTNTTYGGNGGNTCNGGNAAYTTYAGYCCNGARATHATGCARTGY CARACNTTYYTNACNGAYACNTTYTTYATHAARACNGAYTCNTTYTCNAGYGAYMGNCAR AARGTNAAYGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TCNTAYATHAARAAYCCNTCNCCNCAYGTNYTNTCNTCNTCNYTN GTNTAYCCNAAYGTNTAYCARTCNCARYTNATHGTNCCNTCNGGNGARAARACNTAYGAR YTNATHGGNATGYTNACNATHACNGAYTTYATHAAYATHYTNAARCARTAYTAYAAYGGN CCNGARACNAARATHGARGARYTNGARGARCAYMGNATHGCNACNTGGMGNGARTTYYTN AARGGNAARMGNAARCCNTTYGTNTCNATHTGYCCNGAYCARAGYYTNTTYGARGCNGTN AARACNYTNATHGAYAGYCARGTNCAYMGNYTNCCNGTNATHGAYGARACNACNGGNAAY GCNYTNTAYATHYTNACNCAYAARMGNATHYTNMGNTTYATGCAYYTNTTYTTYAARGAY YTNCCNCAYCCNGCNTAYATGAARCARACNATHAARGARYTNGGNATHGGNACNTAYGAR AAYGTNATHACNGCNACNCCNGARATGACNYTNATHAARGTNYTNACNYTNTTYTCNGAY CAYMGNATHTCNGCNYTNCCNGTNGTNGAYAGYAAYTCNGGNAARATHATHGCNATHTAY GCNAARTTYGAYGTNATHAAYYTNGCNGCNGARAARACNTAYAAYAAYYTNGAYATHACN YTNAARCARGCNYTNGAYMGNMGN------TTYGAYAAYCAYCARGCNGARAARGTNGTN TCNTGYMGNTCNTCNGAYTCNYTNGARGAYGTNGTNAAYAARATHGTNAARGCNGARGTN CAYMGNYTNGTNGTNGTNGAYGARAAYGGNGGNGTNGARGGNATHATHTCNYTNTCNGAY YTNYTNAAYTAYACNGTNYTNMGNCCNATGGARGARATHTCNGARGAYGAYYTNGTNGTN YTNGGNACNCCNYTNCCNGARYTNGAYGARACNGARGTNTCNAARAARCCNACNACNATH CARGTNYTNACNGCNAARGAYAARGARGGNMGNMGNMGNTTYCAYGGNGCNTTYACNGGN GGNTTYTCNGCNGGNTAYTTYAAYACNGTNGGNTCNAARGARGGNTTYACNCCNTCNCCN TTYGTNTCNTCNMGNAGYCARAARCAYGARGAYGCNGARGGNTCNMGNCCNGARGAYTTY ATGGAYGARGARGAYYTNGAYGARCAYGGNATHGCNCCNMGNAARTTYGCNACNGCNAAR AAYTTYACNTCNGARGARMGNAARMGNAARTTYGARGAYGTNACNAARAGYTTYACNCAY TCNTCNACNYTNGAYYTNGGNAGYGCNYTNAGYGAYATGGTNATHCCNGARTAYYTNCCN ATHGGNATHAARYTNYTNMGNAARATGGGNTGGMGNGARGGNCARGGNYTNGGNCCNMGN GTNMGNAARAARAARAARAARAAYAGYAAYAARAARAARGGNGGNAARAARAARATHTAY GGNTGYGCNYTNCCNCCNTCNGAYTCNGAYAGYGARGAYTCNGAYTCNTTYATHCCNGCN AAYYTNAGYGAYYTNACNTTYGCNCCNACNGAYGTNACNCCNATHTCNYTNACNGCNAAR GAYGAYGTNAARGGNYTNGGNTAYAARGGNYTNGAYCCNACNYTNGCNYTNCCNAGYTCN CAYGTNAAYYTNTTYCCNGTNMGNGGN---GGNAARAARACNGGNMGNGGNATHAARGGN CAYGCNTTYGGNGTNGGNGCNYTNGARGAYGARGAYGARGAYATHTTYGGNCARGAYTTY YTNTCNAAYTAYGAYYTNACNATGAARGAYGAYGAYGAYGGNCARGAYAGYCAYTTYGGN TGGACNGCNCCNMGNACNCAYGGNAARCARTGYGTNCCNGTNTCNTAYGTNGGNAARYTN YTNGARGGNTTYTGYYTNTCNTCNAARCCNYTNCARACNAARAARAARTTYCCNCCNCCN AGYYTNCCNCCNAAYTTYAARCCNTAYCAYTGGTCNMGNMGNMGNAARACNACN---GAY GGNGCNGAYTCNGGNTCNAARCARAAYCARATGACNGCNGTNGAYMGNGGNYTNATGYTN GGNGARAARCCNATHATGAGYTCNGTNTTYGAYYTNGTNGGNGCNGARGGNAARTCNMGN ATHAAYYTNACNAARGARGCNATHGARATGACNAARTCNYTN------------------ ---------------------CARACNTCNAAYACNTCNTCNAGYGCNYTNCCNATHGTN GAYAARAARGARGARAAYACNCCNTCNACNGARAAYCARCAYCCNAARTTYYTNTCNMGN TTYACNCCNGCNAGYAAYGAYACNAAYGAYGAYAARAGYYTNAGYTCNACNAGYACNAGY ACNACNAARCCNYTNTTYMGNAGYTCNYTNAGYYTNCARCCNTTYCARAARGAYCCNCCN AARCARACNMGNTTYGAYCARTAYYTNGCNGCNGTNCARCARMGNGTNCCNGAYCCNTAY GGNGARGTNTCNAAYAAYMGNATGACNGARTGGGARAARGCNMGNGARMGNGAYGARTTY AGYMGNTCNGCNAARYTNTTYMGNCCNATGTCNGCNATGATGTCNTCNMGNTTYGTNCAY GGNGCNATGYTNGAYGAYAARAAYGARGARTCNAARAARGARGAYAARGARGTNGTNTCN GAYGARGTNAARGCNGCNGARATGMGNATGTTYGGNAARYTNACNMGNCARGARTAYGAR TGGCAYCCNGAYAARYTNYTNTGYAARMGNTTYAAYGTNCCNAAYCCNTAYCCNGGNTCN GAYATHGTNGGNYTNCCNAAYGTNAARMGNGAYAARTTYTCNGTNTTYAAYTTYYTNAGY TTYGGNGAYTAYCARCCN---------AARGAYCCNGTNGTNGCNGAYACNGTNTCNACN GAYAARGAYCCNCARTCNAARGAR---AGYTCNGCNATHCCNGTN------AARGTNAAR CCNTCNYTNTCNTCNATHTTYAARGTNYTNGAYGAYCCNGAYTTYCAYAAR--------- ---TCNCCNCARACNACNACNAARCCNGARGCNYTNAARCARACNGARCARTCNGAYGGN GARCARGAR------------------GARGARGCNGARGTNGAYGTNGAYYTNTTYMGN GCNATHTTYAARAAYTCNGAYTCNGARGAYTCNGARGAR------TCNTCNAGYGGNGAR GARAGYAAYAARAAYAAYAAYGARAARATHATHAGYCCNGTNGAYACNGAYAARAAYTCN TCNGTNATHAARACNGTNAAYCCNGGNGGNCAYAAYGAYCCNCARAAYGTNAAYGARAAY CARCAYAAYYTNAARGAYGAYGGNGAYAAYGCNACNACNCCNCARAARCARGCNGTNAAY ACN---------------------------------AAYAARCCNTTYGCNAGYGTNTTY CARGAYCCNGGNGTNAARTCNATGMGNACNGGNACNMGNTGGAAYACNAARTCNGTNTTY AGYGTNATHGAYGARYTNGAY---------------------------GAYCCNGTNAGY GAYGCNCAYAARGCNACNGGNAAYAARGARGAYGTNTCNGAYGARTAYGGNCCNTCNYTN CCNCCNTCNYTNGARGCNCCNCCNAARTCNTCNYTNAGYYTNTCNTGYGCNGARGAYGTN AAYGARTAYAARAARAARGAYGGNGGNCAYCARCAYYTNYTNMGNGCNAARMGNAARCAY AARAARGARAARAARAARAARTCNAARCAYAARAGYAARGAYAARAARCAYAARAARAGY AARAARTCNTCNAARTCNATHAARGGNAARAARGARAGYTCNGGNAGYGARGCNGAYTCN GARACNAGYAAY------GARGAYTCNGAYAARGARYTNYTNGAYMGNTTYTTYCAYATG TCNMGNATGAARTCNGGNTCNYTNGCNGTNTGYATHGCNGCNGARMGNGCNCARGGNYTN MGNAARACNYTNGARGAYAAYAARTAYTGGGAYTCNAGYMGNAARYTNGGNAARATHCCN GGNGTNGTNGCNATHCCNGTNCAYGAYCARTAYAARMGNCARYTNYTNACNYTNYTNCAR AGYTGGGCNGAYGCNGARATHAARGAYGTNTCNYTNCCNGCNTCNGCNAARGCNGTNMGN AARACNAARGGNGCNATHCARYTNYTNTCNGARGTNCCNAGYAARTGGGARMGNCAYGGN GAYYTNATHATHYTNCCNTCNTCNGCNTTYTCNTCNCCNCARTGGAARCARYTNGGNGAR AAYYTNTGGCAYACNGTNGCNTCNGCNYTNTCNTGYMGNMGNYTNGCNCARCAYTCNMGN GTNGCNAAYGAYTGYTTYMGNACNCCNCARGTNTCNATGYTNYTNGGNCCNGAYGGNAAR GTNGTNCAYGTNGAYAAYGGNATHAARTAYAGYTTYGAYGTNACNAARTGYATGTTYAGY TCNGGNAAYATHAGYGARAARYTNMGNGTNGCNAAYTGGGAYTGYTCNAAYGARAGYGTN GTNGAYYTNTAYGCNGGNATHGGNTAYTTYACNYTNCCNTAYYTNGTNCAYGCNAARGCN CARCAYGTNTAYGCNTGYGARTGGAAYCCNAAYGCNGTNTCNGCNYTNMGNGARAAYYTN TCNYTNAAYGGNGTNCARGAYMGNTGYACNATHTAYGARGGNGAYAAYMGNCARYTNGAR YTNTCNTGYGTNGCNGAYMGNGTNAAYYTNGGNYTNATHCCNAGYAGYGARGGNGGNTGG MGNGTNGCNGTNMGNGTNYTNAARCCNGARGGNGGNGTNYTNCAYATHCAYCAYAAYGTN ACN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNACNATGATGAARGARGARCAYATGYTNMGN ACNAARGTNGAYGCNYTNMGNGCNGARAARACNGARMGNATGAAYAARTAYAAYGARYTN CAYACNAARGAYGAYCARYTNTGYAAYGTNYTNGCNGARATHCCNTAYTAYGTNCCNTCN GGNACNGTNCCNAGYYTNCARCARYTNAARGARYTNGARACNCAYGTNAAYMGNATGGAR ATHGARAARGARAARMGNAGYTCNGARTTYAAYAAYATGAARAGYGARATHTGYGGNYTN TAYAAYGCNATGGARACNGAYCCNGARACNTCNTTYGCNCAYGAYGTNGTNTGYGARGAY GCNGAYACNTTYACNYTNTCNYTNACNCARATGAARAAYYTNAARYTNYTNTTYGAYGAY YTNGTNCAYAARAAYAAYCARATGAARYTNGARGTNGARGAYYTNTGGGAYMGNYTNMGN GCNYTNTGGAAYMGNYTNGARACNTCNGARATHGARMGNGARTCNTTYTCNYTNGAYAAR AAYGGNCAYGGNMGNAARYTNATHGCNGAYYTNAARTCNGARATHGARGTNTGYGARCAR YTNAARYTNCARAAYATHCARAARTTYATHGARGGNATHMGNACNGARYTNYTNACNTGG TGGGAYAARTGYTAYTTYGAYCCNGARCARMGNAARAARTTYACNYTNTAYTAYGARGAR AAYTTYACNGARGCNYTNYTNGARGCNCAYGARAARGARYTNGARAARGTNMGNGAYTAY TAYAARGARCAYMGNGARYTNYTNGARAARGTNACNCARMGNGARGAYYTNTTYAARACN ATGATGGARTTYGAYGCNAARGCNAGYGAYCCNAARMGNTTYTTYAAYGAYMGNGGNGGN AARYTNYTNCARGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATHCARATGGCNCARAARGARTTYTCNGAY ACNTTYMGNTCNCARYTNYTNACNYTNACNGAYGTNYTNCARAARYTNGARATGAAYACN GGNCARGTNTCNGARAAYAAYGARGGNGARAARYTNGTNTTYGARCARYTNTCNAAYYTN YTNGGNATHCCNCCNGGNCARYTNGARTCNCARGCNCAYGGNGGNAAYGTNTCNCCNTCN GARTCNTCNYTNTCNGARGCNGTNGCNGGNGCNGCNTCNATGGAYCAYAARGCNAARAAR CCNGCNAARGGNCARAGYGARGCNAARTCNGARTCNTCNAGYACNGAY------------ ------MGNACNAARTCNMGNGARTTYTGYGARGTNTCNGARGARGARTTYCARTCNGTN TCNAARYTNYTNACNCARMGNYTNAARMGNGARGAYGTNAAYAARGTNTAYAARMGNYTN TGGCARCAYTTYAARGARGARAARAAYAARAGYAARYTNACNCCNAARGAYATGAAYGCN ATGGGNYTNMGNGTNACNGGNGCNACNGGNGARGCNAARYTNMGNATHYTNMGNTCNYTN AARYTNTGYCARATHAGYAAR------------ATGGTNGGNTTYATHGTNCCNAAYTCN AGYYTNAAYTCNTTYGGNTCNATHTGYTAYTGYYTNATHGCNATGGGNATHCAYGCNTAY GCNTGYTAYAAYGAYATHGTNMGNTAYCAYGARGCNGGNGAYMGNGCNTGGCCNGGNACN GGNGGNGARCCNCCNTCNGARGTNACNACNYTNYTNGGNYTNACNATHYTNTCNYTNTTY GTNYTNCCNTTYTTYTGYGTNGCNTCNGTNATHAARGTNGGNAAYYTNGCNAAYGAYGGN GTNAARYTNGGNMGNGAYCARGAYGARAARYTNAARAGYTCNGAYGARGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY TAYGAYATHCCNTGYATHTCNYTNGCNCARAGYYTNYTNGGNAARTAYATHGTNMGNTCN ATHGGNTCNCARMGNATHMGNGGNTGYATHGTNGARACNGARGCNTAYATGGGNCCNGAR GAYAARGCNGCNCAYAGYTAYCARGGNAARAARACNCCNMGNAAYGARGCNATGTTYATG AARCCNGGNACNAGYTAYGTNTAYAAYATHTAYGGNATGTAYTGYTGYYTNAAYATHTCN AGYCARGGNGAYGGNTCNGCNGTNYTNATHMGNGCNYTNGARCCNATHGARGGNCCNGAY YTNATGGCNGARGGNMGNMGNAGYAARACNGAYAAR------MGNAARAARCCNYTNAAR CARAARGARYTNTCNAAYGGNCCNTCNAARYTNTGYCARGCNYTNCAYATHTCNAARAAY GAYTTYGAYAARACNGAYYTNACNGTNTCNGAYTCNYTNTGGYTNGARAAYGGNCCNAGY GTNGAYGAYGARAARATHATHAGYTGYCCNMGNATHAAYATHGGNTAYGCNGAYGAYTGG AARGARAARCCNYTNMGNTTYTAYGTNATGGGNAAYTCNTGYGTNAGYGTNMGNGAYAAR AARGCNGARAAYAAYGGN------AARGGNYTNATGGTNTGYTAYTAYACNAAYTGGGCN CARTAYMGNCCNGGNTCNGGNAARTAYATHCCNAARAAYGTNGAYGCNTCNYTNTGYAGY CAYTTYCAYTAYGCNTTYGCNAARYTNAAYTCNGAYCAYACNATHGCNCCNTAYGARTGG AAYGAYGARAGYACNTCNTGGATGACNGGNATGTAYGTNAARTTYAAYAAYYTNAARAAR ACNCAYCCNCARYTNAARACNATGYTNTCNYTNGGNGGNTGGAAYYTNGCNTCNGGNCCN TTYACNMGNATGGCNGCNTCNAARGARACNMGNGCNGTNTTYATHAARAGYYTNATHCCN TTYYTNMGNAARTGGAAYTTYGAYGGNATHGGNATHGAYTGGGARTAYCCNGGNGCNMGN GGNAGYCCNGCNGGNGAYAARGARMGNTAYACNATGYTNGTNCARGARACNATGGCNGCN TTYCARGARGARTCNMGNGCNACNAAYAGYCCNMGNYTNYTNYTNTCNGCNGCNGTNGCN GCNGGNAARGAYAAYATHGAYTCNGCNTAYGARGTNGAYAARATHAGYAGYGTNYTNGAY TAYGTNATGYTNATGACNTAYGAYTTYTTYGGNGCNTGGAAYCCNTAYACNGGNYTNGTN AGYCCNYTNTAYCCNCCNAARAAYGCNACN---GGNATHGAYGCNATHTTYAAYGTNGAY TAYGCNGCNAARTAYTGGGTNTCNAARGGNTGYCCNAARGARAARYTNGTNATHGGNGTN ATHGCNTAYGGNMGNTCNTTYACNYTNMGNAAYACNGCNGAYACNGGNYTNAARGCNCCN ACNAAYGGNGCNGGNACNCCNGGNMGNTAYACNMGNGARGCNGGNTTYYTNGCNTAYTAY GARGTNTGYAARATGATHCARAARGGNGCNAARATHGTNMGNYTNCCNGAYGARAARGTN CCNTAYYTNGTNTAYCARAAYCARTGGGTNACNTAYGARGAYAARATGAGYYTNGGNATH AARGCNGAYTAYATHAAYGCNGGNGGNTTYGCNGGNGCNGGNATHTGGACNTCNGCNYTN GAYGAYTTYAGYGGNAAYATHTGYGGNGARGGNCCNTAYCCNYTNYTNTCNGTNTTYTCN AAR------MGNCCNYTNMGNAAYCARTCNCARCCNATHMGNGTNTAYTTYACNTTYCAY YTNYTNAGYYTNGTNGARATGGAYGARYTNCARCARMGNATHCARYTNAGYTTYTGGGCN AAYTTYTCNTGGTGGGAYGARATHMGNACNTGGAAYCCNGAYAAYTAYGGNGGNAAYGAY GTNYTNTAYCCNAAYYTNAAYGAYATHTGGMGNCCNMGNACNCARYTNGTNAAYGCNGTN GCNAARMGNGARATHTTYGCNGAYGAYGGNATHCCNTTYTCNATGYTNTCNAAYGGNYTN ACNMGNTGGTAYTGYGCNGAYYTNTTYTAYTTYCARTGYGGNATGGAYYTNACNTAYTTY CCNTTYGAYTCNCARACNTGYGCNGTNAARYTNATGTCNACNCARYTNGGNTCNCARGTN AAYYTNATHCCNGCNATHCCNGTNATHCCNAGYAAYGAYTAYGTNATHAAYAGYGARTGG GARYTNAARTCNACNCARGTNGTNCARTTYYTNGTNACNATHCARAAYGAYTCNTTYTCN TTYGTNMGNYTNATHATHACNTTYACNMGNMGNCCNATGTAYTAYYTNATGAAYGTNYTN GTNCCNATHATGYTNYTNTCNTTYYTNTCNYTNTTYGGNTTYATHGTNCCNAARGARAGY GGNGARMGNGCNTCNTTYTCNGTNACNGTNYTNYTNTCNYTNGCNGTNTTYATGGGNGTN GTNTCNGAYCARYTNCCNCCNAGYTCNGAYACNATHCCNTAYATHAGYGTNTAYYTNTTY AGYYTNYTNTGYYTNAGYACNTTYTCNGTNYTNATHATHGTNTGYCARYTNMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AGYAARMGNGARAARAGY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARYTNGCNATGYTNGARGTNGAYTCNAGYYTNMGNAARCAY GCNGARYTNAAYTAYMGNYTNYTNYTNCARATHCAYGAYGARYTNYTNTGGGARGTNGCN GARGAYCARYTNYTNAARGTNAARGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGGTNGARGCNGAYGTNTCN CCNGGNGAYATHGAYCCNGAYATGCAYGTNGCNYTNCARAAYATHATGGARGARYTNATH GAYGARGTNACNYTNGGNYTNTGYTTYGARATHCAYMGNTCNTGYAARATHGGNTCNTTY TTYYTNGAYGGNGGNGAYGARACNTCNGAYACNGARTAYGCNATHATHGARMGNGCNGGN GTNGAYGTNYTNGGNCARGTNCCNTCNAARAARAAYTAYGARTGYGTNTGYCCNAAYTGY CARMGNCAYYTNGCNGCNTCNMGNTTYGCNCCNCAYYTNGARAARTGYATGGGNATGGGN MGNAAYTCNTCNMGNATHGCNAGYMGNMGNATHGCNAAYAAYCARAARCAYGGNAGYGAY GARAGYGGNCARGAYGAYGARAAYGAYAAYGAYTGGAAYTAYGCNCCNGARTCNAARMGN YTNMGNAARYTNAARAARGAYAARATGTCNGGNTCNCCNMGNAAYMGNMGNYTNGCNAAR YTNMGNAAYAAYMGNAAYGGNCCNAAYGCNGAYCAYCARGGNACNGCNGCNACNGTNACN CCNGCNGCNGTNGTNTCNACNACNGCNACN------------CCNGCNGAYGTNGGNGGN GCNGAYYTNCAYGAYAGYCARGARCARATGGCN------------------AAYTAYGAR AAYATGAGYYTNGARGARMGNAARGCNYTNYTNYTNACNAARTGYGGNGTNATHTCNGAR ATHACNAARAARTTYTGYACNMGNTCNACNAARTGYGCNCARCAYACNGAYGARCARMGN MGNYTNGTNMGNCARAAYYTNYTNMGNCARAGYMGNACNAAYGAYYTNGARGAYATHCAY ATHGAYATHGAYACNTAYGAYGAYGCNGARTCNCARTCNYTNMGNGARTCNYTNCARTGG GARGCNTCNTCNAAYTCNTCN---------------------AAYAAYAGYACNAGYAGY TCNYTNAARCAYCARMGNACNACNACNACN------AAYAARTCNTCNAGYGGNAARTCN AGYAARAGYAARAARTCNAARTCNATHAARACNAGYGTNTCNAGYAGYGGNGGNGGNAGY AGY------------------------------------GARTTYATHTGYAARTGYTTY TAYTCNMGNAAYATHTTYYTNCARAARTAYAARYTNCAYGTNACNTAYYTNAAYGAYAAY CARTTYTAYCARGAYTAYMGNCARGAYYTNMGNYTNAARGGNTGYGCNTCNACNGCNCAR TAYGARGAYGTNYTNGCNGARATHAARATGGARATHTCNMGNMGNAARAGYTTYCAYAGY GAYTCNTTYGARMGNTTYGTNACNATHTCNGARMGNTAYCAYMGNTTYCAYCCNCAYYTN TGGGAYTTYAARTCNTCNTTYGTNGAYGAYMGNYTNTCNYTNATHGTNAAYTCNATHYTN CARTAYMGNACNAARGARGARGCNGARAAYATHYTNGTNTCNAAYGGNGGNAGYATHYTN GGNTCNTGGYTNTAYMGNATHCCNGTNTTYCCNATHAARTTYTGYAARCARYTNGTNGAR GARYTNTCNCAYTTYGARGAYAGYCCNTGYCCNAARGGNMGNCCNAAYACNATGTCNAAY TAYGGNATHTCNYTNGAYGARATGGGNYTNTCNGGNGGNYTNYTNACNCCNYTNATHGTN AAYTAYATHCARCCNYTNTCNAAYGCNYTNTTYGGNAAYTTYTGYAGYGARMGNYTNGAY TCNTTYMGNGCNTTYTCNGTNYTNTAYGGNCCNGGNAARGAYACNCARYTNAGYATGCAY TAYGAYAAYGCNGARGTNACNYTNAAYATHTGYYTNACNTCNCARTTYGARGGNGGNGAY YTNGARTTYGGNMGNYTNTGGGGNGARCCNGAY------------TCNGARYTNCAYAAY GTNACNGTNAARCAYCARATHGGNTCNGGNGTNYTNCAYYTNGGNCARCAYACNCAYCAR GCNYTNCCNATHGTNTCNGGNACNMGNTGYAAYYTNATHYTNTGGATGMGNAGYTCNGCN ATHMGNAAYAARTTYTGYMGNATGTGYGCNTCNACNCCNGAYYTNYTNGAYGTNCCNTTY GCNGGNGAYGGNTTYACN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AAYTTYACNATHCARACNACNTGGGAY GGNCARTGYYTNTGYCAYGAYCCNGTNAARATHTCNYTNGAYCARTCNCCNAGYGGNGAY YTNYTNYTNAARGTNGAYGCNCCNTTYTTYAAYAGYCCNGCNAARCCNGAYGGNCCNGTN GGNCARCCNTTYCCNCARYTNTGGGAYTAYGARGTNGTNGARGCNTTYTTYYTNAAYGAY AARGAYCARTAYYTNGARGTNGARYTNAGYCCNCAYGGNCARCAYYTNYTNYTNYTNYTN AAYGGNMGNMGNAAYATGGTNAARGAYAARYTNCCNYTNCAYTTYGTNGCNTCNATHAAR GGNGAYCAYTGGAGYGGNGARGCNACNATHCCNMGNGAYTAYYTNCCNTCNGCNGTNACN AARTTYAAYGCNTAYGCNATHCAYGGNGARGGNGAYACNMGNCARTAYGARGCNYTNTAY CCNGTN---------AARGARAARATGGARGGNATGCARCCNGAYTTYCAYMGNYTNGAR YTNTTYGARCCNYTNGAYATHGGNTCNATHYTNAGYAAYTAYACNCCNTCNCAYATHTCN GCNYTNTGG------------------AAYGCNCARGCNGARYTNCARCARYTNMGNAAR GARMGNGCNMGNYTNATGGAYYTNCARAGYCARYTNAARCAYYTNCARAGYGTNGTNAAY CARGGNAAYGAYCARCARGARGARMGNMGNGGNGARATHTGYGAYAAYGARAARACNGAR ACNGARCARGCNCCNAAYGCNACNGTNGTNACNTTYGCNTCNAAYGAYGARYTNTAYAGY AARATGMGNMGNCARMGNATHYTNMGNGARGARYTNMGNTCNAARAARAARGARYTNGAR GCNATH------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY ACNATGYTNGGNCCNTCNGARAAYGCNGAYAGYTTYCARCAYGARYTNMGNGGNGTNATH CCNMGNAGYTTYGARTAYYTNTTYAGYYTNATHGCNCAYCARCARGARYTNCAYGGNAGY AARMGNCARTTYYTNTGYMGNTGYTCNTTYYTNGARATHTAYCARGARCARATHTTYGAY YTNYTNGAYCCNACNTCNCARGGNYTNCAYYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AAYACNCCNCCNAAYCCNATHGTNAGYTCNCCNMGN CARTAYYTNMGNACNCCNCCNATGAGYCCNYTNCARTAYGTNGGNGGNACNTCNCCNACN GCNACNGCNACNGTNACNTCNACNACNACNCCNTCNTTYCCNGCNCARCCNTCNCCNTCN CCNCCNGGNAGYCCN---TTYAAYGTNGARTTYAARGTNTCNGARCARGAYATGGCNYTN ACNTCNATHCCNGAYTAYGARGAYCCNMGNTAYTAYCAYAAYGCNCARGGNTGGATH--- GARAGYGGNGAYGGNCAYMGNCCNAARATGGGN---ACNAGYTTYGAYCCNMGNAARMGN AAYTTYACNGAYGARGARYTNAARCCNCARCCNATHATHAARAARTCNAARAARATHTTY GTNCCNGARGAYYTNAARGAYGAYAARTAYTGGTGYMGNMGNYTNAARAAYAAYTTYGCN GCNAARMGNTCNMGNGAYGCNMGNMGNGTNAARGARAAYCARATHGCNYTNMGNGCNGCN TAYYTNGARAARGARAAYAARTGYYTNAARGAYGARATGTCNAARYTNCARAARGARAAY GCNAARYTNAARTCNATHGTNGAYAARTAYGARCCNGGNGCNTCNACNAAYGCNGGNTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNGARTCNGTNAARCCNYTNGTNACNGARGARGARTAYAARAARACNGARTTYYTNTGY CARCARTTYGCNTCNGGNATHGGNAARGARYTNCARAAYAARYTNYTNGCNMGNGCNAAR GGNCARMGNAAYTGGYTNGARAARTGGTGGGARGAYTCNGCNTAYYTNGARYTNMGNATG CCNAAYATHTTYYTNAAYATGGGNGGNCCNGGNCCNTAYACNGARGAYATHTGGCCNCCN CARGARGGNACNCARAAYTTYMGNGCNGCNATGACNACNTAYTAYTCNGTNAARATGTGG CARTTYATHMGNMGNGARCARTAYMGNCCNCAYAARGAYAGYAARGGNMGNCCNYTNTGY ATGCARCARTTYMGNMGNGTNTTYAAYGCNTGYMGNATHCCNGGNGTNTAYMGNGAYAAR YTNCARGARACNTTYAARACNGARTCNGARGGNGAYTGYCCNTCNCAYATHATHGTNATG TGYAARGGNCAYATGTTYGTNGTNGAYCCNYTNGAYGARTCNGGNGARGTNYTNACNCCN YTNGARYTNGARTCNCARTTYTCNMGNGTNMGNCARGARGCNGARAARYTNGGNCCNTCN CARGAYGTNAAYTAYYTNACNACNYTNCCNMGNACNTCNTGGGCNCARCAYMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNACNYTNAAYGAYGTNACNTGYGARGAYTCNGGNCAYTAY ATGTGYATHATHAARTAYTTYACNAGYGARACNAARATGGARAGYGARGCNATHAAYGGN ACNGARACNGCNTCNGCNTTYMGNATGAARGTNATHCCNAAYTAYGGNTCNYTNGARGCN GTNTAYGAYGCNAAYCARACNATHGARGTNACNTGYTTYGCNGARGCNCCNGARGAYTAY AAYTTYTAYTGGAARGAYMGNAAYCCNAAYCCNAGYTTYAAYYTNCCNTCNTTYGTNCAR TGGCCNGTNMGNAAYGAYATHAARGARCAYAARAARAAYGGNGGNCARCCNAAYCARTGY GGNATGTAYAARCAYAGYCARATGYTNATHTTYAARATGTCNGARGAYATGGAYGGNTGY ATGGTNAARTGYGARTTYGGNGARAGYGARTTYTCNTCNTTYYTNYTNGAYCARGTNACN GAYAARACNGCNGCNAAYTCNTCNCCNTCNAGYGCNAGY--------------------- AAYAARGAYYTNATHATHGGNYTNACNGTNTCNYTN---------YTNYTNYTNGCNATH ATHATHGGN---GCNGTNYTNATHTAYGTNTTYTGGTGGMGNAARMGN---AARCCNMGN GARAARTAYAARGAYGARACNGAYGTNMGNAGYGAYGCNGAYAAYAAYCAYCAYGCNCCN CCNTCNATGGTNTAYTCNAARCCNTAYAARCCNCCNAARCAYGAYAAYGAYAARGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARAAYATHYTNATHYTNACNTGYGGNGGNACNATHGAYAARCARTAYCCN CARGGNCCNGGNGCNTAYGCNTTYGARTTYGGNGARCCNGCNGTNGARACNATHYTNAGY MGNATHTGYCCNAGYTTYCARTAYCARATHGARAGYATHTGYGCNAARGAYAGYCARGAR ATHACNGAYGTNGAYMGNGARGAYATHGTNMGNGCNGTNGTNGARGGNGAYCARCARATG ATHYTNATHACNCAYGGNACNGAYACNYTNTGYGAYACNGCNCAYTAYYTNGTNAARGCN GGNGTNGGNCARGGNTCNCARTTYGGNCCNGGNGTNGGNGCNAARACNGTNATHYTNACN GGNTCNTTYAARCCNGARGCNATGAARGAYTCNGAYGCNGAYTTYAAYATHGGNTTYGCN YTNGGNTTYATHCAY---TCNTCNACNCCNGGNGTNTTYGTNGCNATGGARGGNAGYGTN TTYGAYGGNGCNCAYGTNYTNMGNTGYGARGAYGGNAARTTYGTNGAYGARMGNTTYGTN YTNAARMGNTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ACNTCNTGYTCNATHATHGTNYTN ATGTGYATGYTNGTNCARGCNAGYYTNGTNGCNGTNATHGCNTAYMGNGTNATHATGAAY GTNGAYTAYTGYCCNAAYATGCCNGAYAAYGARTGYTTYYTNATHACNACNYTNGCNTCN TCNATHYTNAAYGCNATHTCNATHYTNATHTTYGGNAARATHTAYGAYAARATGGCNGTN GTNYTNACNGAYTGGGARAAYCAYMGNACNCARACNMGNTAYGAYGAYGCNYTNATHATH AARYTNTTYGCNTTYCARTTYGTNAAYAGYTAYGCNTCNTGYTTYTAYATHGCNTTYTTY MGNGGNCARYTNTCNTTYCARGTNATGGTNYTNATGATHGCNAARCCNTTYCCNAARTTY YTNAARGAYATHGCNATHCCNYTNYTNAARAARYTNTGGGCNAARMGNCCNCARTGYMGN ---------AGYAARAAYCARGTNAARGARCARGAYACNGARYTNCARCCNGAYATHCAR CAYACNAAYCAYAARACNTTYYTNGARMGNGARMGNGCNAARCCNGAYYTNGGNGAYTTY ACNYTNGGNGARTAYACNGARAARGTNATHYTNTAYGGNTTYYTNATGYTNTTYGCNTGY TCNTTYCCNYTNGCNCCNYTNYTNGCNYTNYTNATHTGYTAYATHGAYATHAARGTNGAY GCNAARMGNACNYTNTGGYTNTAYMGNMGNCCNGTNATHGGNATGTGGTTYGAYATHYTN CARYTNYTNGTNAARTAYGGNGARYTNTGYAARAAYATGAARACNAAYATHMGNGGNAAY YTNGGNGCNTGGGARMGNGARAARAARCARATHMGNCARYTNGARAARGTNCARYTNAAR CARGCNCCNAAYAGYCCNCARGTNATHAARGCNCARAGYGAYYTNATHYTNMGNGARTTY GTNCARATHGARATGYTNTTYCAYTCNAARGCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGYTNTCNMGNTCNGGNMGNGCNGARACNMGNAGYMGNGCNAARGAR GAYATHAARMGNGTNATHAAYGCNATHGAYAARGTNMGNAARTGGGARAARAARTGGGTN ACNYTNGGNGAYACNTCNGTNACNATHYTNAARTGGGTNCCNATHACNGCNCARGARAAY CCNGGNGCNYTNMGNAARATHCCNGGNGTNAARACNAARACNTAYTCNAARGCNMGNGTN GARMGNGARMGNGARYTNTAYGCNGCNGARACNAAYGGNYTNCCNMGNGCNAAYTCNCCN GCNGAYTCN---AGYAAYAAYAAYAAYYTNTCNAAYACNAGYTCNCCNTCNTCNAARACN CAR------AAYAAYGAYAARGTNAARAAYGGNACNATHGGNAAYAGYCARAGYTCNGTN ATGTAYTCNGARGARAAYACNCARCARTCNATHGGNTCNTTYGGNTCNGARAAYYTNAAY GARGAYTCNAAYATGTCNTTYCCNGARAAYAGYGARYTNAGYGARCARGCNGAYCAYAAY GARTTYTCNCAYGAYAGYAAYGAYGCNGAYCCNGGNATGMGNGTNGCNATGAGYATGGTN GGNGAYGARGARTCNACNAARACNGAYCARGARGAYCARGARCARGARAAYGARCCNGCN TCNTCNGARCAYGAYTCNTCNTCNGAYGARCCNCCNGCNAARAARACNAARCCNGCNTCN ATGTCNGARAARCAYGAYTTYGGNGTNGCNCCNGTNACNTGYCAYGCNTTYAGYAARGAY MGNAAYGGNYTNGCNATGTCNYTNAAYGAYTCNAAYGTNAARATHTAYAARAARTCNGGN AGYAARTGGGAYGARACNGAYACNYTNAGYGARCAYGCNCARMGNGTNACNAGYATHGAY TGGGCNCCNAAYAGYAAYMGNATHGTNACNTGYTCNGCNGAYMGNAAYGCNTTYGTNTGG ATGYTNGARGAYGGNAARTGGAARCARGTNYTNGTNATHCCNMGNATHAAYMGNGCNGCN ACNTGYGTNAARTGGTCNCCNAARGARAAYAARTTYGCNGTNGGNAGYGGNTCNMGNYTN ATHGCNATHTGYTAYTAYGAYGAYGARAAYAAYTGGTGGGTNAGYMGNCAYATHAARAAR CCNATHMGNTCNACNGTNACNTGYYTNGAYTGGCAYCCNAAYAAYGTNYTNYTNGCNGCN GGNTCNACNGAYTTYAARTGYMGNGTNTTYTCNGCNTAYCARAARGARGTNGAYGARMGN CCNGGNGCNTGYTCNTGGGGNTCNAARATGCCNTTYGGNGCNYTNATGGCNGARTTYAGY AAYGGNGGNGGNGGNTGGGTNCAYTCNGTNTCNTTYTCNCCNAGYGGNACNYTNGTNGCN TGGGTNGGNCAYGAYTCNAGYGTNTCNATHGTNGAYTCNTCNAARGGNAAYGARYTNGTN GTNATHAARGARAGYTTYYTNCCNTTYATGAGYATHTCNTGGGTNACNGARAAYTCNYTN ATHGCNGCNGGNTAYGAYTGYAAYCCNATGGTNTTYTCNTTYGGNGGNGGNAARATHACN TCNCARGGNAARYTNGAYGTNCCNMGNGARAARGARTCNGGNACNATGAGYGCNATGAAY MGNTTYAARAAYYTNGAYAARAARGCNACNGAYAGYGAYAGYTCNCCNGARATGAARACN CARCAYCARAAYACNATHACNCARGTNTCNATHCAYACNGGNGAYAARCARAAYGCNAGY AARATHGCNACNAGYGGNGTNGAYGGNAAYYTNATHATHTGGGAYYTNAAR--------- ---------------------------------------------------------AAY GTNACNAGYMGNATHGGNTCNAARGAYAARATGACNCAYAARCCNGGNGGNGGNAAYGTN AARATHGARAGYMGNAARYTNAARGTNGARGCNAARTCNAARATHGGNTCNYTNGAYAAY GCNAGYCAYAARCCNTCNGGNGGNGAYAARAARATHGARAGYAARAARYTNGAYTGGAAR GTNGARTCNAARATHGGNTCNYTNGAYAAYGCNAARCAYGTNGCNGGNGGNGGNGAYAAR AARATHGARACNGTNAARACNGAYTGGAAYGCNGARTCNAARATHGGNTCNYTNAAYAAY GTNAARCAYAARCCNGGNGGNGGNGAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TGGGAYAAYATHGTNYTNCARTTYTCNGARGTN TTYCARACNGARYTNAARGAYCCNAGYYTNGCNGCNMGNCARYTNGARYTNTCNCAYTCN AAYACNACNATHTTYATHTTYCARYTNTGGMGNYTNATHGGNTCNCARTGYATGYTNAAY TAYATHYTNGTNATHATHTTYYTNGAYAARATHTGGGARTTYYTNAARGGNACNCARTAY GTNYTNYTNATHATGATHGTNAGYYTNTAYGTNATGTCNGTNGTNTAYGTNAAYGARATG AARCAYCARYTNCAYYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYAARTAYTTYCAYTAYMGNCARATHTAYCCNGGN TGYAARATHTCNCAYTTYAARAAYYTNCAYAGYATGAGYGGNATHCCNTAYAARGAYATG YTNTTYTTYGAYGAYGARAAYMGNAAYATHAARGAYGTNTCNTCNYTNGGNGTNACNTGY ATGTTYGTNCCNGAYCAYGGNGTNGAYCAYCARTCNYTNAARGARGGNATGGARYTNTTY MGNAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNGCNGARATGTCNGARATHYTNCCNACNTCN YTNMGNAAYYTNGAYTCNTCNMGNGAYGTNGAYMGNATGGTNTCNACNTTYCARGAYAAR MGNMGNCARYTNGARTCNMGNTAYCARCARYTNAAYAAYCARGGNYTNGCNGARAARGTN TTYMGNATHYTNACNAAYCARAAYCCNGARTCNCARGCNAAYGGNATHYTNTCNGARATH AGYGCNGAYGARAARGAYATGMGNACNMGNATGGTNYTNGAYATGCAYGAYAARAAYTTY AAYTAYTCNTCNACNTCNAGYTGGYTNGAYGAYGTNAAYCARAGYTTYAAYCCNAAYTGY GAYGTNMGNAARAARYTNGAYATGTCNGGNYTNAGYTCNATHGAYTCNAGYYTNGCNTTY GAYAARTCN---ACNAARGGNTTYTTYGCNYTNGAYGAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGAARGTNTAY CARTGYYTNATGTCNGGNGAYGARATGTTYACNGARACNACNCCNATGACNGARACNGAY GGNTTYTAYATHYTNAARGGNAARTTYGTNACN---AAR---GCNGAYGGNGTNGAYGAR AGYYTNYTNGGNGCNAAYCCNAGYGCNGARGARGCNGCNGARGGNACNGARGAYGGNACN ATGGARTCNGGNGTNGAYGTNATHATHTAYCARMGNYTNCARGARACNGGNTTYGGNTCN AARAARGAYTAYCARATHTAYATGAARGAYTAYATHAARAAYGTNTTYTCNAARYTNGCN GARAGYGGNAARTCNGCNGAYGARYTNGCNATGAARGARAAYGTNGCNATHGCNTTYAAR GARGCNTGYGCNAAYTTYAARGARTGGCARTTYTAYTCNGGNGCNAGYATGGAYCCNGAY GGNCAYATHGCNYTNGTNGAYTGGAARGAYGARGARGTNGAYGGNAARACNGTNAGYACN CCNTAYYTNTAYTTYTAYAARGCNGGNATHAAR---------GGNGCNGTNGGNTGYMGN AGYCARAAYGARYTNATHGAYATHCARGAYGAYGTNAARGCNGGNACNTTYACNGTNAAY GARGCNGTNATGYTNTTYAAYGCNTGGAARGARMGNTAYCARACNGGNAGYAARGCNGTN AGYTTYAARGAYAARCARAAYTCNYTNGARATGMGNCARAARTAY--------------- ---------------------------------------TTYGTNGTNGCNGTNTTYYTN TGGAAYGTNGTNYTNCCNGAYGTNCARGGNATGGGNATHGTNAAYMGNTGYTCNAAYYTN TGYGCNGARGARACNAARGCNAARTCNGCNTGYGTNATGGARMGNAAYTGYYTNGTNCAY ATGTTYAGYGAYAAYATGGARAARTTYGCNACNTGYACNGARCCNTGYACNAARATH--- GGNAAYTGYTTYCARMGNTGYGCNYTNGGNGCNGAYATHATHAARCARGAYTGYGAYGAR YTNTGY------------------------------------------------------ ---------TCNCCNMGNCAYGCNMGNGARTAYGAYGGNGCNGAYAGYTCNGAYYTNGAY GARAARGAYCCNGAYGGNAAYATHTCNGAYGARGAYACNGCNGAYGCNAGYGARACNGAR GARAARACNCCNAARTCNCARAARAAYAAYTTYCCNAAYAGYGGNAGYCARMGNACNGAR ATHAARGARCARATGTAYCARGAYAARYTNGCNCARATHAARAARCAYATHCARATGYTN GARGARGGNACNYTNCARGARTTYYTNAARMGNACNAARAARATHGARYTNAAYTAYMGN GARMGNYTNMGNGAYAAYGARATHTGYAARAARGTNGAYATHGARAARGCNGARCARAAY TAYYTNGTNGAYTGYGARAAYGCNCARAARGARTTYGARGARAARMGNGARACNATGAAR GARAGYYTNATHAAYCAYYTNAARGARAARAARATHGAYYTNAARGARACNYTNATHACN GAYYTNAARGARAARMGNAGYATGATHGARATHGARMGNCARAAYGTNGAYYTNAAYGGN GCNGAYTTYATGGARGTNAARCCNACNATGACNMGNAARYTNMGNMGNMGNCCNAAYGAY CCNATGCCNATHCCNGARAARMGNMGNAARCCNTCNCCNGCNCARGTNAAYATHYTNYTN GAYGAYGAYTTYATHATGGCNGAYYTNMGNYTNATHATGAARGTNAGYGGNAARCCNGTN GCNAARAARCARGGNYTNGGNGCNCAYCAYAGYATHGTNGAYACNTCNTCNGAYGTNMGN ATHGARGAYGGNMGNYTNTGGTAYGAYAARAARTGGTTYCARMGNAAYACNATGGTNCAR ATHGAYAAYAARGARACNGGNTCNMGNATHCAYGGNACNATHACNAAYATHYTNAAYCAR GARATHTGGGTNAARAARAGYGGNGAYAAYTCNAARYTNMGNATHTGYYTNTCNCARTTY CARAARGGNAARTAYAAYATGAARAARMGNACNTCNACNYTNGGNMGNACNGAYTAYCCN TCNGGNATGAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARGCNGAY YTNGGNTGGACNCARGAYGARGARCCNGARCCNGCNGARACNGAYTGYTGGGCNCARGGN TCNGTNCCNMGNAAYGTNATHYTNGCNCCNACNCCN------------GARYTNGARGAR ATHCCNGARGARTCNGARGAYATHGCNCARGARGARGARGARAARGARGTNGARCAR--- GARAARGTNTCNCARGARCCNCCNGARYTNGAYGAYGTNGTNTCNGARGCNGARGARACN CCNGARATHATGGCNGARCARGARAAYAARGTNGARAARGTNCCNTCN---------CCN CCNAARGTNACNYTNGCNAARACNAARAARAARTTYMGNCCNTAYMGNGGNAARYTNAAR TCNGCNGGNGTNAGYAARATGACNGARTCNYTNGARGARACNGARATHAARATGATHTAY GAYGAYTTYGTNGCNTCNATGCCNCCNTCNGARGAYAARCCNAAYACNYTNYTNAAYATG CCNGCNTCNTGYACNAGYATHYTNAARGTNCARACNGGNMGNCCNCCNGGNAAYAARGAY GTNGTNTAYGAYGAYYTNGGNAAYGTNGTNGCNGTNATGAARYTNGAYCCNGARAARYTN CCNACNCAYAARGTNAAYGTNAARTAYCAYGTNGTNGAYCCNGCNGTNGARGCNGCNCAR GCNMGNYTNGAYGCNATGMGNAARGGNAARTCNACNGGNAGYAARATHMGNAARATGAAR CCNACNAARACNYTNTCNTCNGAYTCNGTNTCNGCNGGNAGYAARACNAARATHCCNGCN TCNTCNAGYACNGTNGCNCCNYTNCCNCCNCCNYTN------------------------ ---------------------------------ATHGARGARATGGARGTNTCNCAYGGN GTNATHATHMGNGARGGNGGNMGNGTNAARAARGGNCCNGGNMGNTAYTAYMGNAARYTN GAYGTNYTNGARGARCAYCARAARGGNATGAARCCNGTNAGYGTNMGNYTNACNAAYTCN GGNATHACNGTNAAYGAYYTNYTNGAYMGNAAYACNCCNATHYTNMGNCCNYTNGCNGAR GCNTCNCCNYTNCCNCCNATHGTNCCNCAR------CARCARTCNTCN---CARGTNTCN ATGGTNCARGTNGCNGTNATHGGNGCNGGNGTNGTNGGNYTNAGYTCNGCNTGYGCNGTN CARAARYTNYTNCCNAAYTCNAARGTNACNATHATHGCNGAYAARYTNGGNGCNGARYTN GTNAGYCAYGGNGCNGGNGGNGTNTTYMGNCCNCARATGGARGTNYTNYTNAAYGARCAY AAYGGNCCNYTNATHMGNCARTGYYTNMGNGAYACNTGGAAYCAYYTNGCNGGNYTNGCN ATGTCNAGYYTNGCNAARGAYTCNGGNCARATGATGGTNGCNGGNYTNYTNTCNCAYMGN AARCCNATGGAYGARTCNTAYTCNATGYTNAARGARTGYTCNYTNGAYTTYCAYMGNYTN ---TCNGARACNGAYATGMGNAARMGNGGNATHGARGARTTYAARTAYACNTAYACNTGY ACNAAYATHATHTCNCARCCNGAYGTNTAYYTNCCNTGGYTNACNAARCARTTY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GAYGAYAAYCCN CCNGCNCCNGGNTCNCCNCCNYTNCCNAARAARGGNGCNTAYAGYATHGAYTTYGAYAGY YTNGAYGARTTYTCNAAYCCNTTYGARTCNAARAGYAARATGAARATGGGNTCNTCNTCN CCNATGCAR---------------CCNAGYACNATHCAYTTYGAYGARGAYGTNGAYCCN TTYAAYTCNAARAARAGYYTNGCNAAYTCNCCNCCNGGNTCNCCNAARYTNAARACNCAR TGY------GARGARGAYAAYMGNGARGCNGARTTYGGNGGNTCNACNCCNCARGTN--- ---------------------GARGGNTCNGARACNCCNGTNAAYAAYGARAAYGAYATH CARGTNACNYTNAARAARAARAARATGATHAARAARCCNCARGTNCARTCNAARTTYAAR CCNCCNAARAAYYTNAARMGNAAYAARAAYGAYGGNGAYATHGARATHYTNATGCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARTCNATHCARTCNTGG--------- AAYCCNYTNGGNYTNMGNCARYTNYTNAAYYTNATHMGNCAYMGNTAYGGNAAYCCNCCN GTNGTNATHAGYGGNAAYGGNGTNTGGGAYGCNGAYGARGTNGARGAYATGTTYMGNTCN GAYTAYATHACNCARCAYYTNGARGARGTNYTNAARGCNATHMGNATHGAYGGNTGYAAY GTNACNGAYTAYTCNTAYMGNTCNYTNYTNGAYAGYTAYGARTGGGAYTAYGGNACNAGY MGNAARTTYGGNYTNGTNAARGTNGAYTTYTCNTCNCARGGNYTNGCNMGNACNATGAAR AARTCNGCNATGACNTAYAARGAYATHATHGCNAAYMGNGGNATHYTNAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARGARGGNMGNGARATGGGNGGNYTNATHYTNATHYTN GCNTGGACNGGNATHTCNMGNTTYTCNCCNTTYGGNAGYACNAGYTCNAARTCNCARAGY AAYYTNATGACNGGNYTNYTNGCNGTNGCNTTYACNYTNGCNGTNGTNCCNYTNYTNACN TGGTCNYTNTGYTTYGTNGGNGAYTGGCAYAARCAYYTNGGNCAYTGYTCNGGNATGTTY TGYCCNTGGTGYGAYAARGTNTAYTTYAARAARCAYTCNYTNAAYTGGCAYATHTCNAAY CAYTGGAARGTNMGNACNCAYAARTGYTCNGTNTGYCCNTGYGCNTTYTTYACNGTNCCN CARYTNAARGARCAYTTYCARACNCAYACNGAYGGNAAYCCNTAYMGNTGYGCNATHTGY GGNGARGTNTGYTCNAAYAGYMGNGCNYTNAARMGNCAYACNGAYGTNCAYGARATHGGN CARAARTTYYTNTGYAGYYTNTGYGGNAARGARYTNTAYTGGGCNMGNGARYTNGAYGTN CAYATGMGNTAYCAYTCNGGNGARAARCCNTAYAGYTGYTCNACNTGYAAYAARTCNTTY AARTCNMGNGCNAAYYTNAARATHCAYATGGARACNCAYAAYGGNAARAARGARTAYYTN TGYGAYGTNTGGGGNAARTCNTTYMGNGGNTTYATHGTNTAYTCNMGNCAYATGMGNATH CAYACNGGNGARAARCCNTTYAARTGYAARYTNTGYGGNTTYGARTTYGGNCARAGYTGY ACNYTNAARMGNCAYATGAARACNCAYGAYMGNGARACN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNACNGGN ACNCCNYTNCARAAYAGYYTNYTNGARYTNATGTCNYTNYTNTGYTTYGTNATGCCNGAY ATHTTYGARGGNAARACNGAYCAYYTNAARAARATGTTYGCNATGATHTAYMGNTCNGAY GAYAARCARAARAGYMGNTAYGARMGNCARMGNATHGCNCARGCNAARMGNATHATGAAR CCNTTYATHYTNMGNMGNYTNAARAARGAYGTNYTNAGYCARYTNCCNAARAARGARGAR AARGTNATHAARTGYCARATGACNGARTCNCAYAARAARYTNTAYGARGGNYTNGTNTCN TGYTAYGCNCARGARGTNGARAARGGNGAYACNYTNTCNTCNAARAGYGGNATHGGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYGTNGTNTGGGCNTTYAAR YTNGARCAYATHCARCCNAGYTTYAAYTCNYTNTAYTTYTCNGCNTCNTCNGARAARGAR ATGGTNAARTGGATGMGNGTNATHAARYTNGARATGYTNGCNGCNAAY------AGYAAY TCNGTNMGNGAYTCNCARTCNCARTAYAAYGARTCNATHGCNTCNGARGAYTCNTGGCAY TCNTCNGAYTAYGAYYTNYTNGARAGYAGYATHTAYGAYGTNCCNGTN---AGYMGNCCN ATGTCNATGTGYAGYCARAAYAAY------------------------GGNGAYTTYGAR GARGGNGGNGARYTNAAYCCNAGYAAYCCN------------------MGNAARYTNMGN ATHGCNCCNCCNGGNGCNGGNTAYGAYYTNGARAAY------CCNATGTCNAARMGNAAY CAYGARGCNGARACNTAYTGGAAYGCNTCNAARTTYAGYGGNCARAARGTNGARGCNTCN GARATHATHAGYAGYATHGGNGAYGAYGGNGTNTAYYTNYTNMGNAARAGYGARGAYAAY TCNAAYGTNYTNGTNGTNTTYTCNGGNGCNGTNAARAARTAYAARATHYTNAAYCARGAR AAYGGNAARATGACNYTNAGYGCNAAYGARCCNCAYTTYAAYAARATHGARGARYTNYTN TAYCAYTAYTAYAGYAAYAAYYTNCCNAAYTCNAAYCARAARYTNAGYTGYCCNTTYAAR YTNCAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGGCNGAYTCNAARTCN AGYYTNGCNMGNGAYGGNACNATGCARGTNACNGCNAARGARGGNATHGAYTAYYTNAAR TCNGCNCARAARGAYACNYTNYTNAARGCNCARGGNYTNATHAARGAYAARCCNGTNGTN CARMGNGAYGGNACNATGGTNTCNACNGCNAARGARGCNGARMGNYTNYTNGAYGGNAAY MGNCCNGAYGCNGAYGCNCARACNMGNGGNCARCARAARCARATHGARGARYTNAARAAY ---------GARCCNMGNGCNAARAARGCNAARYTNACNAARGAYGGNACNATGGCNGTN ACNGCNAARGARGCNAARGCNYTNYTNGCNGGNGARAARYTNGGNGAYACNMGNCARGAR ACNAARAAY---------AARACNAARACNCCNYTNMGNAARAGYACNACNATGGCNMGN ACNGTNGARGARGCNAARGGNGTNYTNGAYGGNAARGTNGAYTTYAGYGARGGNMGNAAR ACNMGNTCNCARAGYMGNGGNGAYGCNCCNAARCCNGCNATGAARAARYTNGGNACNATG CARCARACNGCNAARGAYGGNAARACNTTYYTNAARMGNACNAAR---GGNAARMGNACN GCNAARGCNATGGAYGARGAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------AGYMGNYTNGCNTCNYTNCARAARAGYGGNATHCCNGGNTCN------GGN YTNGGNMGN---CARTTYGAYTCNAAYACNTTYACNMGNCCNAARMGNCCNGCNAAYTCN AAYGGNCCNTTYCAYGGNGARGGNGAYCARGTNCARAAYGTNCCNAAYGTNGCNGAYATH GARAAYYTNGCNAARCARCARGARGARAGYYTNMGNCARAGYGTNACNCCNGCNAARAAY ACNYTNMGNAGYAARCAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGCCNAAYYTNCCN YTNGTNAARCAYATH---------------------ATGGCNGCNGTNGGNGCNAAYACN GCNMGNGCNYTNAARCARGTNATGAARCCNCAYATHCCNTCNATHAARTTYCCNAARMGN GARCCNGTNAGYGARYTNCARGCNGCN------CCNGTNGGNAAYCCNAAYTCNYTNGAY TTYYTNYTNTCNAARAAY---------------GTNGCNTCNAARCCNTCNTCNAARACN GCNAARGGNCCNTCNATHGARTCNTCNGARYTNCCNATHMGNTTYCARMGNAARCCNYTN ACNCAYGARGARATGGARTAYATHGARAARGGNGGNCCNGTNGTNGCNTGGYTNYTNTTY YTNTGYGTNGCNYTNAGYGCNTTY------------GARAARGGNGARTTYGGNGCNTGY GTNGARGARTGYAGYATGGAYGCNTAYAGYTTYGGNYTNGGNCARTGYCCNTCNGGNCAY GTNTGYGCNTCNAAYGGNTGYGGNCAYACNTGYCARCCNGTNAARMGN---------GAY ACNCARCCNGARTGYCCNGARGTNGTNTGYTTYATGTAYTGYACNTAYGGNTTYGCNAAR GGNATHGAYGGNTGYGARATHTGYGCNTGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CAYATHCAYACNCARACNTCNCCNYTNYTNTTY CARGTNACNGAYAARYTNTGYGGNGARCCNATGAARMGNMGNMGNAARYTNGAYCCNGCN YTNACNGCNGCNMGNACNCARAARAARYTNAARAARATHGAYAARGARATHMGNMGNYTN TCNMGNTTYGGNAARATHYTNAARCCNGTNGARGARATHGARGGNGAYMGNMGNAARYTN ATGGCNTCNGGNGARMGNMGNMGNGARCCNGTNGTNYTNACNTTYGARGARTCNGARTCN MGNGCNYTNYTNCAYAARGAYTGGACNTGYTAYMGNACNAARMGNCAYCAYGARYTNGTN ACNATHTTYTCNAARGTNTCNGCNGCNCARCARGARGCNYTNGAYGARYTNMGNGCNGAR TCNGARGARYTNTTYYTNGCNGCNATHAARAARGAYGARAAYYTNATGMGNYTNACNTTY GAYGGNCCNAARGARACNCCNCCNATHAARGAYTAYGTNGTNCCNGAYGGNGARTAYTTY GAYACNACNMGNAARTAY---------------GAYATGGARTGGAAYATHGAYATGGAR GTNAAYYTNTTYCAYGCNATGMGNGGNCAYAARCCNGCNGGNGTNAAYMGNCAYTTYCAR ATGATHGCNATHCAYGARAARYTNAGYTCNTCNGCNAARAARGTNACNTCNAGYGAYGTN TGGAARCAYYTNTCNACNYTNTAYGAYYTNCARGCNYTNAAYGARTCNGARATHGTNCCN TTYCCNAAYAARAAYGGNGAYTTYGCNYTNGTNGAYAARGARATGYTNGAYYTNTGYTCN AARTCNTTYCCNMGNTCNTCNTAYATHAGYAGYGTNCCNAGYGAYTCNGTNAARTCNGAR GGNGCNGGNAARACNATHTCNAARTTYAGYACNAARCAYGARGGNAARCARGGNCCNCAR ACNCCNAARGTNGAYGGNAARAGYGARCARAAR---TCNTCNCAYATHTCNAARGCNGAY AGYMGNTCN---AGYACNCCNAGYMGNTCNGARTCNAARTCNTCNCAY---AAYAGYAGY ATHAAY------TCNAGYAGYTCNAARTCNTCNCAYCARAAYACNCCNTCNACNGCNCCN TCNCCNTCNTCNAARMGNACNAARMGNACNMGNACNGTNAAYTCNGCNTCNGCNAGYCCN GCNACNCCNACNGARCCNCARTCNAARMGNMGNMGN------------------------ ------------------------------------------------------------ ---------------TAYTAYYTNYTNACNGARTAYCCNAARGAYAAYYTNYTNAAYGAR TCNATHAARGCNGAYGGNCCNCARTTYCARGARCCNCARTGGGTNGCNGTNAGYGARCAR GCNAARGAYYTNYTNMGNGARATHYTNACNCARGAYCCNGCNCAYMGNATHTCNTCNGGN GARGTNYTNAAYCAYGARTGGTTYACNGGNAARAARMGNGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNCAR ATHACNMGNGTNTTYMGNTTYTTYMGNYTNGTNAARGAYGTNATHGGNTTYMGNGTNYTN YTNYTNTCNATHMGNACNTCNTGGMGNGARYTNYTNYTNYTNYTNYTNTAYATHGTNATH GCNGTNTCNATHTTYGCNACNGTNGTNTTYTTYTGYGAR---------MGNGARAAYATG AARTCNATHCCNGARGCNTGYTGGTGGGCNATHATHACNATGACNACNGTNGGNTAYGGN GAYATHTAYCCNGTNTCNYTNCCNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNGAYGAYGAYATGAAYYTNAARYTN GCNGAYCAYTCNAGYAARGGNTTYGGNTAYGTNTCNGARGARYTNGTNGAYCAYYTNAAY GAYCARATHMGNCARATGAARGAYGARAAYGGNMGNYTNTTYAARYTNGTNAGYGARAAR GAYTTYGARATHMGNCARTTYAARAARAARAARGARGARCARGCNTCNAAYACNATHGAY YTNTCNGTNACNAGYGARACNGCNGCNACNAARATHGTNGARYTNAGYAARAARGTNMGN GARYTNACNGCNGARAARGARTCNGARAARACNMGNTGYAARCARTTYCARAARAARTGY CAYGAYYTNCARYTNCARYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARAARMGNGARATHACNCARAAYTTYTAYACNGAY TTYATGAARAARACNGARGARGAYYTNAARGAYYTNGGNACNATGATHGAYMGNGARAAR GARGARGCNGARGARAARYTNAARAAYGAYCCNAARYTNAGYAARGAYCCNCARGCNYTN GARACNGARYTNCARAARYTNCARACNCARTTYAAYCAYAARCARGGNAARYTNCARAAR GAYTTYMGNGAYAARATHMGNYTNGAYYTNYTNMGNTCNTCNGGNATGCARGAYTCNGAR GTNGARGARGTNATHTCNGAYYTNATGGAYAAYATGGCNCAYGTNGARGARAARYTNGGN YTNGARCARGCNMGNCARMGNMGNTCNYTNGARCARMGNYTNGCNAARMGNAARCARGCN ATGGARTAYCARCARATHGARACNCARGARAARGCNAARGARCARGARGCNAARATGAAR ATGTTYMGNAGYYTNYTNGARAAYCAYACNAARGAYGGNTCNYTNYTNGARMGNCARCAR GAYTCNATHATHGAYTAYTAYGCNAAYGARAAYGAYYTNYTNAARAARTAYCAYGCNAAY GARTTYAARGGNYTNTGYYTNGAYAARTTYGARYTNYTNCARCARGAYMGNYTNAAYAGY TTYAAYAARYTNAAYMGNAARCAYGAYAARGARAARGCNGCNTTYYTNCAYAGYGCNGAY AARACNACNAAYCCNTCNGARTTYATHAARYTNTAYCAYGAYYTNATGACNAARCARCAY ATGGARAARGARGCNYTNTCNGGNGAYYTNGAYATGMGNGARATHCARGARATHTAYMGN YTNAARGARGARAGYGARAARAARGARGCNAARGGNATGAAYAARYTNATGGARAAYATG GAYGARCARATHGARGGNTCNTCNAAYATHACNTCNAARGARGCNGCNAARYTNATGAAR ATHCAYAARGCNGARATGGARAARTAYCAYGCNMGNACNCARMGNGAYAARCARGCNATG YTNGCNMGNYTNCARGARAARYTNCARCARMGNYTNGARGCNGCNGAYGARAARGARGCN ATHGAYCARAARGARCARGARACNYTNAARGARCARCARATGGCNACNYTNGAYAARGTN YTNGCNACNAAYYTNGAYYTNACNGARGAYGCNAARGARMGNATHATGMGNGARCAYGAR CARAAYATGCARGCNATGTCNAAYCARYTNATGMGNAGYAARYTNMGNCARCARAARAGY YTNGARATHAARYTNAAYCARMGNAARGCNAARYTNGCNGARYTNAARCARAARMGNGAR ---CARYTNCCNGGNGCNMGNCCNGGNAGYGGNAARAARGARAARGCN------AAYATH ATGAGYYTNGAYCARCARATHGCNAARGARGARGCNAGYTTYAARGARGCNMGNCARGCN GCNGARGCNGARYTNMGNAARCARYTNGCNGARGARACNGARGARGCNYTNAARCARCAR GAYGARGARATHGGNYTNYTNATHGGNMGNYTNCARGCNGGNCARGCNMGNMGNAARGCN GTNYTNGARAARCARGAYGCNGTNYTNAARGAYYTNCARGARAAYYTNGARMGNCARGTN TCNTCNGCNAGYGGNYTNAARCCNTCNATGACNGAYCARATHYTNAAYCARCAYTAYGCN AARATHTCNAAYYTNAAYGARCARYTNCARMGNCAYAARGAYGAYCAYGARMGNMGNATH YTNGARAARYTNTCNCARAARMGNGTNCARAARGARCARCARYTNGARTCNCARYTNGAR CARGARGCNCAYTTYGARTAYACNCARAARCARAARMGNGGNGCNGGNTAYGCNAGYYTN GTNYTNATGCARTCNTTYYTNGARCARAARCAYGCNAARGCNYTNAARGARYTNGARYTN GARATGAARGCNGARYTNGARAARAGYAARAGYGARYTNAAYTCNCARYTNGARGTNGAR YTNMGNAARGARYTNGAYGCNCARMGNCARAAYATGYTNACNCAYYTNGCNGCNGTNAGY GAYGTNTCNTCNGCNGAYYTNCARAAYGCNGTNAAYGCNAARGCNTCNGGNCARGCNGAY AGYAARGTNGCNAARMGNYTNGCNAARGAYYTNAARGARAAYGTNGARMGNGCNMGNTCN TCNATG------AAYMGNGARGAYCCNMGNGAYGAYGAYTTYGGNTAYMGNMGNAGYAAR ACNGAYATHGARAAYAARCARGGNTAY---AAYATGAARGGNMGNAARGGNTCNGCNGTN TCNAAYMGNMGNMGNGGNGCNGCNMGNCARGCNTTYGCNGAYGARGAYGAYGARGAYGAY ATGGAYATHYTNTAYATHTCNGTNTGYTTYATHGCNYTNTTYATHAGYTCNTCNTTYGGN GAYACNGAYCCNYTNGARGTNAARTTYGARAAYGCNACNMGNGTNGAYGCNATGGARGGN GCNGARATGATHCAYTTYMGNTGYCAYYTNAAYMGNGGNGCNATGTAYGTNATHYTNAAY AARGTNGARATGATH---------------------CAYGTNGAYCCNYTNACNTCNGAR GARACNATHATHAGYTCNGCNAAYYTNGTNGARGGNAARCCNCARTTYTAYGAYGTN--- AARATHTCNCARAAYACNGAYAGYAAYGCNATGATHGTNGAYTTYACNGTNYTNGARGTN MGNTTYGAYGAYGAYGGNAARTTYATGTGYAARGTNTCNCCNGGNGAYAARTCNGAYGAY GAR------------------MGNGARGTNGTNGTNCAYMGNCCNYTNTCNTCNYTNAAR YTNAARATGGGNGAYTTYGAYAGYATHGARGARTCNCCNAAYGAY------------CCN YTNMGNATHGAYCCNGGNGARTAYAARGTNACNTGYGTNGCNGARGGNAGYAAYCCNGCN ACNGARGAYGTNGAYYTNACNTTYCAYGGNYTNGARTTY---GGNTCNGGNCARCCNGTN GTNTCNGCNATGGARGGNCCNGARMGNAARTTYMGNACNGTNGTNAAYGGNAGYYTNAAY ATHATGGTNAGYAAYAAYCARCARGARYTNYTNTGY------CARGCNCARGAYTCNACN GGNACNTCNAARTCNGTNAARYTNACNGTNGARGTNAAYATHTAYGARCCNGTNGTNTTY TGYAAYGAYACNGARGCNTAYCARGGNGARAARAAYCCNATHYTNTAYTGYACNGTNAAY CAYACNGGNYTNGARGTNGARGGNTTYTCNTAYCARATHGGNGAYACNGGNGAYATHGTN AARGARGGNGARAARAAYGAR---------AARAAYATHGTNGTNYTNGTNTCNAAYGTN CARCCNGGNATHTCNGTNGTNTCNYTNGAYYTNCAYGARGCNCAYCCNCAYTAYYTNGAY AARAAYTTYTAYGTNYTNGTNTAYYTNAARGGNGGNCAYACNTCNAARGCNAGYGTNMGN YTNAAYMGNATHGARGCNCCNCCNACNGARAAYAAYAAYGGNAAYAAYAAYGAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATHMGNYTNACNGARACNTCNTCNTGYTAYGGNGGN GGNGCNCCNGGNYTNTCNGAYGGNTAYGTNGCNGGNTTYYTNTGGYTNGAYAARYTNGGN YTNGCNGCNAARTAYGGNGTNACNMGNGTNTTYMGNCARACNTTYTAYGGNGGNAGYTAY GCNYTNYTNTCNCCNAARYTNGAYCCNAAYCCNGAYTAYTTYYTNTCNYTNYTNCAYAAR CARYTNATHGARGGNCAYGTNTTYAAYGCNACNGTNCARCCNAAYACNMGNTCNYTNMGN ATHTAYGCNCAYTGY---ACNMGNGAYTTYGGNYTNTAYAARAARGGNGCNATHACNYTN GCNTAYYTNAAYACNAARAGYGARTCNTCNCCNATHAGYYTNAGYCARTTYTCNAARTCN TAYTTYGAYYTNTAYATHYTNACNCCNGGNGAYTCNGAYGGNYTNAARTCNMGNTTYGTN AARYTNAAYGGNGARGTNYTNAARATGTCNGGNTCNTCNYTNCCNCCNYTNAAYCCNAAR CCNCAYAARGGNGAYATHGTNYTNCCNCCNYTNTCNTTYGGNTTYATHGTNATHCCNGAR GCNAAYGTNTCNYTNTGYAARMGNYTNACNGGNGCNGARGGNGAYATHAGYCARYTNTTY GGNGCNGARGAYGTNGAYTAYMGNAGYATHAAYAARMGNATHTCNAGYATGGTNCCNCCN CCNCCNATGCCNTCNTCNGTNYTNYTNTCNCCNCCNGTNAARAGYAGYGCNCARGTNGGN TGGAGYCARTTYAARGARAARCAYCCNGAYGAYTTYGTNCARGARACNGARMGNAARMGN YTNMGNGAYGCNCARATGCARGARGTNCARGAYGTNGAYYTNMGNCARTCNTCNACNCAY YTNMGNATGATGCARCCNCAYATGAAYAARCARACNAAYCCN------ATHTCNYTNGAR AGYAARGTNAARATHYTNCARCAYGCNGARATGGARGTNCARGARGGNMGNATGACNAAR GARGAYCAYCARGARYTNYTNMGNCARGTNGGNCARGTNTAYAAYMGNAGYAAR---TCN MGNGARGGNCCNGARGGNCCNAAYATHATGCAYGAYCCNMGNATHMGNGGNAGYMGNGAY AGYMGNTCNTCNGAYGCNCAYMGNAGYCAYCCNAAYGARCCNGTNGAYMGNCCNTAYATH CCNGARCCNMGNMGNGGNAARAAYACNGARCAYMGNTCNCCNYTNTAYCARGAYMGNMGN GARAAYMGNMGNTTYGTNMGNAAYMGNGGNGAYGARGAYTCNCCNCCNGGNAAYMGNMGN GCNATGCAYAAYCARGARCCNGARAAYATGMGNGAYMGNMGNGAYGGNGGNCAYATGGAY GAYTCNGAYMGNGAYTTYMGNCARGAYGTNTCNMGNTCNCARCCNCARATHYTNGGNCCN AAYGCNCARTCNGTNCCNTCNATHCCNGARGGNCARGGNYTNCAYAAYCARGGNCCNAGY ATGCARAAYGCNGTNGGNCCN---------------MGNCARYTNGGNCCNGCNATGGCN GGN---------------------------------------YTNCCNCARAAYAGYGCN YTNCCNCCNMGN------------------------------------YTNCCNGAYTCN GTNCCNCCNTCNTCN--------------------------------------------- AARATHTCNGAYCCNYTNGAYGAYCCNMGNTGGTCNGTNATGAARGGNYTNYTNGAYTCN GAYGGNACNGARGARGTNGTNYTNGAYGAYAARCCNTTYGARYTNMGNATGGGNACNGCN MGNAARYTNCAYYTNTAYAAYCARGTNTTYGARGTNMGNGTNGAYATGAARGARMGNGGN ATHTGYATHAAYGGNCARYTNYTNTAYAARYTNGGNGARCCNATHAARGARGTNAAYATH AAYGGNMGNMGNGTNMGNYTNTAYTAYCAYGGNYTNCCNAARCCNATHTGGYTNGAYGGN CARTAYCAYGARATGMGNYTNGAYGCNCCNCCNMGNAAYGTNYTNATHGAYGGNTGYCAR MGNGGNTTYCARATHGAYGGNMGNGAYATGATGATGYTNGTNGAYMGNATHGARAARGGN CCNTAYGGNGGNCCNCCNMGNAARATHMGNATHGTNGGNGTNGARCAYGAYATHAGYTTY CARTTYCCNCCNMGNACNATHYTNATHGAYGGNAARCCNTGYGARYTNAARYTNGAYAGY AARATHCCNTTYGTNGTNATHGARGGNAARCCNCAYGGNATHMGNTTYGAYGGNGARCCN MGNACNATHTTYATHAAYAAYYTNCCNTTYACNATHCCNYTNGAYMGNGCNGARAARATH MGNATHGGNGCNMGNCCNATGTAYATHGCNTTYGGNGGNCCNGCNCAYGARYTNATHATH GAYGGNAARTGGTTYGARGTNAARTTYAAYAAYACNCCNAARGAYATHCAYYTNGGNAAY MGNMGNTTYAAYGTNMGNATHCCNGGNCARYTNCCNMGNGTNAARATHYTNGAYCARYTN CCNATGAAYTTYGAYGTNTCNMGNYTNATGGTNAARAAYACNGTN--------------- ---------------------------GARGTNCARMGNGARATGCCNACNACNATGYTN CARTCNGGNATHCCNGGNGTNCARTCNCARMGNCCNGTNGGNAAYATHGTNCARAAYYTN GCNAARCCNMGNACNATHAAYCCNGAYCARATHGGNCARGGNCARATGYTNMGNCCNTCN YTNGGNACNATH---------------------------------GGNCCNATGCARGTN CCNCCNAAYGTNAARCARCCNGTNACNCARATHCARGTNCCNAAYCARCCNMGNYTNCCN CAYGGNATGGTNCCNACNYTN---CCNGTNCARCCNGGNATGGTNCARCARACNGCNGGN GTNATG---------MGNCCNGGNATGATGMGNCCNCARGTNGTNGCNAAYCCNGTNGCN CAR--------------------------------------------------------- ------------------------------------------CCNATGGGNATHGCNGGN TCNCARATHGTNTCNCARCARCCNATGGAYGTNATHGCNTCNGARYTNATHAAYCAR--- ------------------------YTNACNAAYATHAAYCARGCNGTNCCNGGNAAYATH ------TCNATGGCNGCNCCNGTNACNYTNGGNCAYGTNYTNGARAARACNAAYCCNAGY CARGTNAAYGGNGGNTCNATHGCNCCNATGGCNGGNATGCARGGNTCNGTNATHAAYCCN YTNGTNCCNAGYTCNGTNCCNAGYATHAAYAAYGCNACNCCNAGYACNGGNGTNGARACN AAYACNAAYACNGTNGGNGTNCCNCARGTNCAYTCNATHYTNACNYTNCCNGCNGGNYTN CCNGGNATGYTNTCNTCN---------------TCNGARAGYACNACNAAYACNTCNACN ACNACNTCNAAYTCNTCNGGNACNYTNGAYATHAAYAAYYTNYTNAAYAAYYTNYTNAAR GCNGGNYTNATHAARGAYACNAARTCNACNGAYGGNGCNCCN------------------ ---------------------CCNTCNGARGAYTCNAARGAYATHAARCCNACNYTNAAY CCNATHAARGAYAARAARAARGGNCAYATHCCNAAYYTNTCNGAYTTYGAYACNGAYYTN YTNAARATHGCNTAYCARMGNGTNATHGAYGARYTNCAYGARGGNATHCARTGYCAYACN TGYTCNGCNMGNTTYACNACNGAYGAYCARGAYAARTAYMGNGCNCAYYTNGAYTGGCAY TTYMGNCARAAYAARYTNGARCARGARATGATGAARGTNGCNAARAAYMGNAARTGGTTY TAYACNATHGCNGAYTGGATHCARTAYGARGARYTNGARGAYYTNAARGARAARTCNMGN AGYGARATHTTYGARCARATGMGNTCNATHAGYGARCARCCNGGNAGYGAYGTNCCNATH MGN------------YTNYTNGCNYTNGARGGNAARAAYGTNGTNAARGARCCNGTNGTN ACNGGNGGNGARGGNGARGAYGTNTGYGCNACNTGYGGNGAYTCNTTYGAYCARGTNTGG AAYGARGARAARCARAAYTGGATHYTNAARAARGCNGTNATGGTNAAYGGNAARATHTAY CAYCCNGTNTGYGTNGARGAYYTNCAYGARACNCCNACNCCNGTNGCNGAYTTYGTNACN AAYYTNYTNGAYAAYCARATHYTNGAYAARAARGARGARATGGTNGAY------CCNYTN CARCARGARCARGAYGTNAAYTCNTCNGTNGARCARCARGAYATHAARCCNGAYATHCAY AAYYTNGARYTN------------------GARACNCARGARAAYGTNGGNGAYGGNATH GAYAAYAAYATHGGNGTNAARGARGAYTCNGGNGARCCNTTYATHAARACNGARGTNGCN GARGGNYTNTCNGTNGARGARCCNAAYTAYGAYATHAAYGTNTCNGARAARGGNGARTAY YTNCARTCNAAYGARACNCCNTTYGTNTCNGCNYTNAAYAAYACNACNATHMGNAARGTN ATHTCNGTNTGYACNGARGAYCCNAAYTCNCCNTGGGARATGGAYTCNAAYCCNACNCCN GARYTNTCNMGNACNCCNAGYCCNATHCCNYTNAARMGNCAYYTNMGNGTNCAYACNGGN GARAARTCNCAYMGNTGYGTNGARTGYGGNAARGTNTTYMGNGARATHTCNCAYYTNAAR AAYCAYYTNMGNATHCAYACNGGNGARAARCCNTAYGTNTGYCARGTNTGYGGNAARGCN TTYMGNCARAGYGGNGGNYTNCARGTNCAYGTNMGNACNCAYGAYMGNGARAARACNCAY GTNTGYCCNATHTGYAGYGARTCNTTYGTNMGNATGAGYCAYYTNAARGCNCAYAARMGN CARACNTCNCCNCARMGNMGNCAYAARTGYCCNGTNTGYGAYGTNGAYYTN------MGN GGNAGYYTNAARYTNCAYATGAARACNCAYGCNGGNGARAARCCNTTYATHTGYGGNGTN TGYGGNAARGCNTTYATHMGNAGYGARACNYTNGARGTNCAYATGMGNAARCAYACNGGN GARCAYCAYYTNCARTGYTTYGTNTGYGARACNTCNTTYGARAAYAARAGYTGYYTNAAR ACNCAYATGAARTCNCAY------------------------------------------ ---------------------------------------------GARGARGAYGARGAY GAYGTNGAYGARTTYACNGARGAYGARATHGCNAAYGAYCCNTCNAARMGNATHYTNTGG GCNTCNGARAAYAAYAARGTNGAYATHGTNGARCARATHYTNAARGAYGAYCCNCARYTN GTNTCNGCNTGYGAYAAYGAYMGNTAYACNCCNYTNCAYMGNTGYTCNTAYAAYAAYCAY CCNGARGTNGCNAARATHYTNYTNTCNTAYGGNGCNTGYGTNGAYGCNMGNACNGTNGAY GGNTGGCARCCNYTNCAYAGYGCNGCNMGNTGGAAYTCNGTNGARACNGCNCARATGYTN ATHCAYAAYGGNGCNGAYGTNAAYGCNYTNACNAAYGGNMGNYTNACNCCNYTNCAYATG GCNGCNTCNGARMGNGARAAYGGNMGNATGYTNGARYTNYTNYTNCAYAAYCCNTTYATH AAYGTNAAYATHGTNTCNAARGGNGGNGARACNGCNMGNCARATHAGYCARMGNACNAGY GARCAYCAYCARYTNTTYGARTTYATGGAYAARAGYGTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARCARYTNAARAARGCNATGGARGCNYTNACNAAYAGYGAR ACNGCNGTNGARGARYTNCARATGCARYTNAARAARGARMGNGCNGARTTYGARAAYAAR YTNMGNAAYCARGCNAAYYTNTTYGAYCARGAYTCNAGYGAYGARGTNGCNGCNYTNCAR CARCARGTNGCNACNYTNAARAARATGATGGCNGAYCARAAYGTNGTNATHYTNGGNYTN AARMGNGARYTNACNGAYYTNGARMGNACNGAYMGNATGACNTCNAGYAARCAYTCNAGY MGNACNAGYGTNTGYTGYTTYGTNAGYGGNATGMGNTCNGGNTAYYTNTAYGARYTNTTY CCNTTYYTNAAYAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CAYGCN YTNTAYTCNAAYTTYAARATHGARGGNGARMGNGAYMGNTAYMGNYTNCAYGCNTCNGGN TTYTCNGGNAGYGCNAARGAYTCNYTNCAYMGNCAYAAYAAYAARCCNTTYTCNACNGAR GAYMGNGAYAAYGAYAAYMGNCAYGAYGCNAGYTGYGCNAGYGARTGGGARGCNGGNTGG TGGTTYGAYAARTGYTGGTAYGCNYTNYTNAAYGGNCCNTAYCARAGYGAYGTNMGNTAY AARGGNATHGCNTGGAARAGYTGGAARTTYGARCARYTNMGNGGNTCNGARATGAARATH MGNCCNCARYTNCARGCNGARGTNCARMGNYTNAARMGNGARAAYATHGCNYTN------ ---------------AARYTNTCNATGYTNGARAARAAYAAYAARGTNGARGARAARYTN AAYGCNATHATGGCNAARCARAAYAAYATGACNCARGARGTNGCNAGYYTNTCNTCNGAR TTYGGNTCNAARGTNGCNAAYYTNACNGAYTCNYTNCARACNATHAAYACNAAYAGYYTN GCNGCNTGYACNYTN---------------------AARTCNGCNTCNGCNTAYAGYAAR ATHCAYGTNGARACNGAYTTYGTNCCNTCNATHGARGARTTYAARAAYAAYTTYGTNGCN TTYGCNTTYTGYACNTAYYTNGGNATGTCNGAYGCNAAYYTNGAYGARCARGARACNAAY TCNCAYGTNCARTAYMGNTGYMGNTGYAARTCNAARAARGGNYTNACNTAYAARGCNTGY ACNATHTAYTAYTGGYTNTGYCCNMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GGNAARYTNAAYACNYTNGTNYTNTGY CARGGNGARGAYAAYGCNTGYATHAGYYTNACNTGGGAYCARAARATHACNATHTGGAAY ACNGTNCAYAARATHGCNYTNAARACNATHTCNATHCCNTCNGAYTTYCCNTGYYTNACN GCNYTNATHGAYGCNMGNGCNGTNAARGGNTTYATHYTNTTYATGGCNTTYTGGMGNGTN GARGARYTNGGNGAYTGYGGNGGNGTNATHGTNYTNAAYCCNGTNACNGGNYTNYTNGGN AARACNAARGTNTGGAAYATHCCNAAYTCNGGNTGGAARAGYACNGARAARGTNAAYAAR GTNGAYAGYCAYATHTTYGCNTCNAGYAGYACNGGNTCNGTNTCNTGGTGGAAYGGNCAR ACNGGNMGNATGGTNGGNTAYMGNCARTCNAAYATHGCNACNTGYGTN---------TTY CCNTCNCAYYTNCCNMGNGGNACNACNACNYTNTCNGTNCCNAARTCNTCNGCNYTNYTN MGNCCNGGN--------------------------------------------------- ------------------------------------------------------------ ---------AARGARGARYTNATHMGNAARYTNTCNMGNMGNYTNYTNTAYYTNATGMGN TAYGGNGCNYTNAARGARGGNYTNGAYGTNGAYGAYAAYGGNTAYGTNCAYATHGCNGAY YTNATGAARGTNCCNYTNYTNAGYGTNTAYTCNCARGARGARGTNYTNAAYGARATHAAR ACNTCNGTNTCNTAYMGNAAYACNAAYMGNTAYGARTGGMGNGARAARGAYAAYAARATH TAYGCNMGNGCNGCNTAYYTNMGNMGNTTYGARYTNAAYCCNTTYCAYTTYGGNACNCAR GTNAARACNYTNGCNGARACNAGYATGACNTGYGTNYTNAAYAAYYTNGAYCARTTYGAY YTNGARGAYTTYCARGAYGARTAYACNATHAARYTNATGATHCAYMGNYTNAARMGNCAR AARGCNATHAAYAAYAARGCNYTNTCNATHYTNTTYGTNCCNACNYTNACNMGNGTNGAY YTNGARGGNATHTAYYTNACNAAYAAYACNYTNMGNYTNYTNTGGACNCARTGYCCNCAY YTNMGNGGNATHAAYYTNAARAAYTGYGGNTAYATHATHACNGAYACNATHYTNTCNCAR YTNACNAARAAYYTNCCNAAYYTNGARCARYTNAAYYTNAGYMGNTGYTCNCAYYTNACN GAYAARTGYYTNTCNATHYTNTCNAARMGNYTNCCNCAYYTNAARGTNYTNCAYATHGCN GGNGTNCCNTCNATHAAYCCNAARTCNGTNCAYAAYTTYTTYAAYTCNTCNAARGARYTN ACNTGYYTNGAYGTNTTYTAYATGAARACNACNCARGARGARTTYGAYTCNYTNATGAAR CARGCNGARAGYYTNGGNGTNCARYTNATHYTNCAYCAYCCNAAR--------------- ------------------------------------------------------------ ---------------------------------GGNTGGACNGTNGTNCARAARMGNCAR GAYGGNAGYGTNGAYTTYTAYMGNGGNTGGGARGAYTAYMGNMGNGGNTTYGGNAGYYTN GARGGNGARTTYTGGYTNGGNAAYGAYAAYATHCAYTAYYTNAGYTCNCARGARCCNACN ATGYTNMGNATHGARATGGARGAYTGGAAYGGNAAYTTYCAYTAYGCNGTNTAYGAYTAY TTYMGNGTNGAYAGYYTNAARGAYAARTAYMGNYTNCAYATHAGYGGNTAYCAYGGNAAY GCNGGNGAYTCNATGACNTCNYTNTAYGARAAYCAYAAYGGNATGCCNTTYAGYACNAAR GAYMGNGAYAGYGAYGGNMGNTAYTAYGAYTCNTGYGCNATHCAYTAYAARGGNGGNTGG TGGTTYAAYAAYTGYTTYGARGCNCAYYTNAAYGGNAARTAYGTNCCNTAYYTNGGNAGY AARATHAGYYTNATHTCNAARGCNGARATHMGNTAYGARGGNACNYTNTAYACNATHGAY CCNAAYGARGCNACNGTNGCNYTNGCNAARGTNMGNTCNTTYGGNACNGARGAYMGNCCN ACNGAYMGNCCNYTNCCNGCNMGNAAYGARGTNTTYGARTTYATHATHTTYMGNGGNCAY GAYATHAARGAYYTNCAYGTNTGYGARCCNCCNAARCAYAGYCAYACNGARGGNGGNGTN CCNCCNGAYCCNGCNATHGTNAARTCNTCNCARCCNCCNCCNGGNCCNGCNGGNGCNGCN TTYCAYGGNCARGCNGGNTCNGGNGGNCARCCNCCN---------TAYCARCCNTTYACN CAYCARCCNYTNTTYTAYAAYCARGGNCARCCNGCNCCNGGNTAYCCN---CCNCCNCAY CAYGGNCARGGNGGNTCNCARGARGARGTNTCNCCNATHGTNGARCARTCNCCNGARCAR AAYGCNCAYGCNTCNGTNACNGCNATHGGNTCNMGNCCNATHTCNGGNTCNCARACNTCN ACNCCNCCNYTNAGYMGNAARTCNCCNACNTCNGAYCARGGNGTNCARGTNCARCCNMGN AGYCCNGARAARTCNAGYAAYGARAGYCARCARAARCAYGCNCCN---CAYAGYCAYCAR CARCAYCAYCAYCAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNATHYTNGTNCAYACNAAYGTNYTNTAYTGYGAR GTNATGGGNGARGCNATHCAYYTNCCNTGYYTNAARAARYTNGTNTTYCAYGAYYTNCAY GCNAAYYTNYTNGAYCAYMGNCAYGARAGYMGNMGNATGTAYAAYAARMGNGTNACNATH CARGTNTCNCARCAYTGYACNGAYYTNGARTGGGTNGARYTNTAYACNATHTGGGCNGAY YTNGAYAAYGAYGTNATHCARCARTTYACNAARAAYTGYCCNAARYTNAARMGNYTNAAY YTNACNTGGTCNTCNCAYYTNACNGAYMGNGCNTTYGTNAAYACNYTNGCNTGYTCNAAY ATHACNCAYYTNGGNYTNGCNGAYMGNCARGARMGNGARCCNTAYYTNAAYTTYGTNYTN CCNCAYTTYCCNCAYYTNATHTCNYTNACNGTNAAYGGNMGNGAYGTNCAYTCNGAYGAY TGYYTNGCNYTNAGYAAYTTYTGYCCNAARYTNCARGARYTNGTNTTYGARYTNAARAGY ATGMGNGAYCAYGAYTGYYTNTTYGAYTTYTAYYTNCAYCARCAYAAYTCNYTNTCNGGN YTNAAYYTNCARAAYATHGTNGARGGNTGYMGNCARYTNMGNAARYTNCAYGCNCCNTGY TCNAARGTNGAYGAYGAYAGYATHATGAARYTNTCNGTNAAYTGYCCNTTYYTNGARGAY GTNAAYTTYATGCAYTGYCCNYTNYTNTCNGCNCARTCNYTNATHGCNYTNTCNGARAAY TGYGCNYTNATGAARTTYGCNAAYTTYCARCAYACNTTYAAYCCNCAYGAYTAYYTNCAR GARTTYATHGARAARTGYTCNYTNYTNCARGARATHAAYTTYGAYATHTCNTGYTCNCCN YTNCCNTCNCCNGGNAAYTCNGCNTGYGCNTGYAGYTCNYTNTCNMGNYTNCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYTAYCCNGCNGARGTNGARGTNTCN TAYGAYGARTTYAARTAYGTNGAYAARYTNYTNCCNAARACNACNGTNCCNGARGTNCCN GAYCAYCCNTCNTAYCCNACNCCNTCNGGNTGGATGCCNCCNAAYGAYGARATHMGNTCN CARCARCCNTAYYTNGTNCARMGNACNAARAAYCAYGTNYTNCCNGTNTAYCCNAARGAR MGNGARGTNTGGGGNMGNATHATGCAYCAYGTNATHATHAARAAYATHGAYGGNGAYATH TGGAARYTNGARGCNGARYTNMGNGGNCAYYTNCARGGNACNACNCARGCNGGNAARATH ATHACNCARGTNCAYGARGTNAGYMGNTGYATHMGNATHMGNGGNCARCAYMGNGCNGCN ATHGCNCARTTYYTNYTNGAYAARGGNATG------------------------------ ---------------------------------------------------------TTY AARYTNACNGGNGGNACNGTNYTNAAYAAYGAYCCNMGNATHYTNMGNTCNMGNYTNATH MGNGARYTNCARGCNAARTGGAARGAYGGNATHATHTAYGGNAAYATHGGNTAYTAYTGY GGNGCNATHTGGYTNMGNATGCAYTTYGAYACNTCNAARMGNAARAARAAYAGYTCNAAR GTNATGGAYGAYTAYAAYCCNAAYAAYTCNGTNTTYATHYTNCAYTAYCARGGNTCNCCN TAYYTNATHATHAGYAAYACNMGNGTNAARGARGCNACNYTNYTNACNCAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARATGGAYTGYYTNATHCCNYTNCARCAYAAYATHAAYAARYTNGTNYTNGTNGGN GAYCARGARCARYTNCCNGCNACNGTNYTNTCNCARGARGCNAARAAYTTYMGNTTYGAY ACNTCNYTNTTYCARMGNYTNCAYTCNAARTTYGARTGYGAYAARAAY---GAYAAYCCN GTNATGATGYTNAARGARCARTAYMGNATGCAYCCNGARATHYTNAARYTNCCNAAYTCN TAYTTYTAYAARAAYYTNYTNACNACNGCNCARTCNTCNYTNAARTCNAGYACNTCNAGY YTNAGYCCNTAYYTNGTNTTYGAYYTNYTNGAYGGNYTNGARTGYTCNGGNAAYCAYGGN TCNAARTCNAAYAARAARGARGCNACNTGYGTNGGNYTNYTNTGYGARMGNGTNGTNAGY YTNATGGCNAARAARAGYAGYGGN------AGYGARTGGCARAARAARATHGGNGTNATH TGYCCNTAYACNGAYCARAARMGNGARATHCARGAYATHYTNAARMGNMGNGGNYTNTTY AAYATHYTNGTNAAYACNGTNGAYAGYTTYCARGGNCARGARAARGAYGTNATHATHYTN TCNTGYGTNMGNGCNCARGGNAAYCCNCARTCNGTNGGNTTYATHGAYGAYTGYAARMGN ATGAAYGTNGCNYTNACNMGNGCNAARYTNGCNYTNTAYATHGTNGGNCAYGGNAARACN YTNAGYACNTCNGARYTNTGGAARYTNYTNTAYCARGAYGCNAARAARMGNGGNYTNYTN GTNACNGTNCCNMGNACNGAYYTNTTYTCNGAYGTNGCNTAYAARMGNGTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AGYAGYCCN AGYACNMGNGCNATHYTNGAYTCNATHAAYGGNGAYTGYTCNAGYGCNGARMGNAARGAR AARYTNYTNTCNGCNATHGAYAARMGNGTNCAYYTNAARATGGCNTCNAGYCCNTCNAAY CAYYTNMGNAGYCARCCNAGYCARATHCCNMGNTTYATGGCNTTYYTNACNAAYAARAAR AARGAYGAYCARAAYTCNACNACNCCNGGNGGNAARAAYTGGAAYAARATHCAYAARAAR GARTTYTCNAARTTYGAYTCNATHGAYGTNTAYYTNGARAARAARCARCARMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGGAYTTY GGNTCNAARTTYGTNTAYYTNGGNAAYGARGARGCNGAYGARGARGARGTNAARGTNTCN AAYGARGAYGAYATHGTNYTNTCNGAYAGYGAYGTNAGYGAYGAYGAYGGNGARTCNTGY YTNYTNGAYATHYTNGAYACNGCNGGNCARGARGARTAYTCNTCNYTNAARGAYCARTAY GTNMGNAGYGGNGAYGGNTTYGTNATHATHTAYAGYATHACNGAYCARGARAGYTTYAAR GARGCNGARGCNATHTTYMGNTGGYTNAARMGNYTNMGNGAY---GAYAAYTGYCAYGTN ATHYTNGTNGCNAAYAARCARGAYYTNAARGGN------GARGCNAARGTNAGYGAYCAR GARGGNAARGAYYTNGCNACNAAYYTNGGNATHCAYTTYTTYGARACNTCNGCNAARGAY GGNACNGGNGTNAAYGAYGCNATGAARGGNYTNGTNMGNATHATHCCNMGNACNGGNAAY GAYTAYAARATHGTNATGYTNGGNGGNGGNGCNGTNGGNAARTCNAGYATHACNYTNMGN TTYGTNAAYGGNATHTTYGTNGAYGAYTAYGAYCCNACNATHGARGAYTCNTAYMGNAAR ATGATHACNGTNGAYGGNYTNACNGCNGTNAGYAARGAYACNMGNAARGCNGCNAARAAR GCNAARAARTCNAARAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNGTNTTYGGNACNYTNTAYCCNGCNTAYGCNTCNTAYAARGCNGTNAAR ACNAARAAYGTNAARGARTAYGTNAARTGGATGATGTAYTGGATHGTNTTYGCNYTNTTY TGYTGYGTNGARACNTTYTCNGAYGTNTTYYTNTCNTGGYTNCCNTTYTAYTAYGARYTN AARATHATHTTYGTNATHTGGATGYTNTCNCCNYTNACNCARGGNTCNAGYTTYATHTTY AARAARTTYGTNCAYCCNCARYTNGCNMGNMGNGARAARGAYATHGAYGARATGATHGCN CARGCNAGYAARCARAGYTAYAGYACNYTNYTNTCNYTNGGNTCNAARGGNGTNAAYTAY GCNTCNCARATGGTNATGMGNACNGCNATHATGGGNCARTCNAARYTNGTNGAYCAYYTN MGNMGNAGYTAYAGYACNAGYGAYYTNACN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TCNATHGAYTAY ATHCARTCNCAYAGYGGNAAYAGYCARGARGCNTGGMGNCCNCCNACNYTNGAYGARACN GAYGAYGARGAYAAYACNAARCCNGARGGNCCNTGYTTYATGTAYGGNGARMGNATHATH AGYMGNAARATHMGNMGNYTNGCNMGNCCNATGTCNGCNATHGARMGNTCNMGNCCNAAR AGYAGYGGNAGYAARAAYMGNCCNAAYAGYGCNATGGGNTGGYTNAARYTNAARACNAAY ACNGARTCNGTNGCNAAYACNGCNMGNTCNAGYMGNCCNAGYGCNGTNTCNTCNTAYGCN TCNGARMGNGARCCNTGGGARGAYGAYACNTCNGTNATHACNAARAARATHYTNAARTCN CARGCNMGNTCNCARATGGGNAARMGNGAYTCNGTNTAYCARTCNGCNGGNGCNGTNATG ACNTCNCARTCNTCNAARAARGTNMGNGAYYTNGCNMGNAARATHMGNATHAAYTCNACN CARATHACNATGAAYGAYGTNGAYCCNTCNTTYGCNMGNCAYCARGGNYTNYTNGARGAY AARCCNCCNAARMGNCCNAGYACNGCNAAYGAYGTNYTNGGNMGNMGNGCNACNTTYGGN GARATHATGAAYCARMGNAARCCNACNYTNAGYGCNGGNGCNTGGMGNCARCAYYTNAGY AARAGYAAYGCNACNCCNATHTCNGTNTCNGCNCARCARAARGCNATGYTNGARGCNAAR AARCAYYTNAAYGAYACNMGNMGNGCNGAYGTNGARGARAARGTNMGNGAYTTYATGCCN ATGCCNGAYATHTCNGAYYTNGCNGTNCCNTCNGCNCCNCAYATH---------TCNCCN TCNATGNNNAGYTCNTCNATGCAYGGNGGNTAYGCNAAYGCNGCNGTNTTYAGYCAYAAY MGNTCNCAYAGYYTNACNATHGAYATHGAYGAYMGNACNGAYAARAARAGYTCNACNAAY AGYYTNAAYTCNTCNAAYTTYAGYYTNGGNGAYYTNGAYGAY---------GCNATHGAR MGNAARCAYATGTCNGCNGCNGAYATHGAYAARATGCARCARGARATHCARTCNYTNMGN AARTCNYTNYTNAGYGCNAARMGNGAYMGNTGGGTNAARYTNCCNGTNCARGAYACNYTN MGNMGNATHATGAARGGNGARTCNTAYTCNYTNGARATGTGYMGNTCNYTNGCNGAYAAR MGNGARYTNGTNGAYYTNGCNGTNMGNACNCAYGAYGGNAAYGCNATHACNGCNACNGTN YTNTTYATGAARAARACNACNAGYTCNCARATHTTYAGYMGNGARYTNAARCARMGNCCN GTNGCNGCNAAYCAYTAYYTNCAYTTYYTNAARGARCAYTAYGAYTTYACNGARTAYATH GARACNYTNTGYYTNYTNGGNMGNACNGARGARGCNGGNATHTTYAARTTYCARYTNGCN YTNCCNACNCCNGAYGTNACNYTNAARATHTCNAARYTNAARGAYTCNYTNMGNACNTAY TTYAGYGCNGAYCCNACNYTNTCNTCNCAYGCNTCNYTNGTNCARGARTAYATHGAYYTN YTNGARMGNCARMGNCCNATHGARGAYTCNGAYTCNATGTGYGARGCNAGYGGNCARAGY CARYTNTTYAARGAYTTYCCNMGNAARGARTCNYTNGTNGAYATGCCNGTNATHACNACN YTNTAYTAYTGYTCNYTNTAYCAYTTYGAYYTNTCNGARAAYTCNYTNGGNAGYCCNACN GCNATHMGNAARMGNCAYCARATHTCNGARAARCARTTYGTNTGGACNTCNGTNGGNGCN MGNGCNAARYTNMGNCARTGGMGNGAYATHGARGCNATHYTNACNACNAARGGNTGGTTY GGNGGNACNAARYTNAARGCNGTNATHGGNTTYGAYAARATHGTNGGNATHYTNCAYAAR TAYAAYGCNCCNCCNGAYATHYTNGAYAARTAYYTNTCNYTNATGGAYGAYCCNGARGCN MGNYTNAAYYTNGCNAARAARGTNAAYTGYCCNAARGCNGTNATHGAYACNTAYGCNTCN YTNAARGAYMGNTCNTCNYTNGARAAYTAYGCNTCNACNYTNGAYMGNTAYTCNAARGAY GGNYTNTAYGCNYTNGAYGTNYTNAAYGGNTCNACNTTYAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARTGGACNGTNACNGARGTNTAYGARTTYGTNYTNTCNYTNCCNGGNTGYTCNGAYTAY GCNGAYGAYTTYMGNTCNCARGARATHGAYGGNCARGCNYTNYTNYTNYTNAARGARGAY CAYYTNATGACNGCNATGAAYATHAARYTNGGNCCNGCNYTNAARATHTGYGCNAARATH AAYTCNYTNMGNATHGAYCCNYTNCCNTTYCAYACNTCNAAYYTNTCNAAYGTNAAYCAY AARAARGARMGNGCNATHGTNAARCAYYTNTAYTAYGTNGAYCAYGARAARACNYTNAAY CAYTCNTAYAGYCCNYTNGTNGARYTNCCNGAYTAYACNTAYCARGAYGARAARCCNACN GARATGACNYTNTCNTAYAARMGNAARCARGARAARAAYTAYAAYYTNGCNAARCARGTN GTNAARYTNGTNGARGARATHAARTTYGCNCARAAYCARTTYTCNTCNCARGARGARGTN AARGTNAARTAYGARGARCAYMGNAARAARTCNCARYTNAARGGNAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TAYTTYATHYTNACNATGGCNATHTTYGAYYTN ATHGCNTGYGTNGTNGGNATGCCNACNGARATHTAYGAYYTNAAYAAYCCNTAYACNTTY TAYAGYCCNATHGGNTGYAARATHTTYMGNGGNTGYGARACNTTYACNATHTAYGGNTCN GCNATGATHYTNGTNGARATHGCNTTYGAYMGNTAYTTYAARATHTGYMGNCCNYTNYTN ACNAARGGNAARAGYCCNYTNATHTCNTCNCAYTAYCCNAARCARCCNTGYCAYTCNATH AAYCCNAARGCNACNTGGACNCARAARGAYCCNCCNGGNTAYTTYTTYAARGGNGARTGG CARTCNTAYYTNTGYTCNMGNTAYGTNAARMGNGAYTGYYTNMGNAAYAARTAYATHGTN ACNYTNGGNGAYTCNAAYACNMGNAGYCAYTAYTAYAGYYTNATGGGNYTNYTNGARTGY AARCCNGTNYTNAARGCNYTNCAYGARAARTGGCAYGCNCCNYTNAARGGNGTNTGYCCN GARTTYAAYTCNACNATHACNTGGAAYCCNCAYTCNGARCCNTTY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGTCNATHGARYTNGTNTCNAARTGYYTNGARYTNGARGARYTNAGYAARGTNAARGGN GAYAGYTCNAARGGNAAYAARAARAARAARATGAARACNAAYGAYGCNATGCARGTNATH AARACNAAYMGNGARGGNGTNTGGAARGARYTNMGNAARATGMGNAARAARCARYTNAAR GARATHAARAARAARMGNAARACNGARAARTTYAARTCNGCNATHGARATHTAYAARGAY GARCAYGAYGTNGAYCAYACNGAYMGNAAYGTNGARACNYTNYTNAARATHTCNAARYTN GGNAARGTNAARGCNGAYTGYGCNCARAARATHYTNTAYGARCARCCNTGYMGNYTNTCN MGNGAYATHGCNGARAARATGGARGARGCNGARCCNACNTCNGTNTTYACNGAYGARGAY TTYGCNAAYTTYGCNAARGAYTAYCAYCCNAAR---------ATGTCN------GTNCCN CAYACN------------CCN---CCNGTNAGYGGNGGNAAYCARCARGAYMGNCARAAY MGNAARYTNYTNYTNGARCAYATHCARGARCARAARAARMGNYTNCARCAYGGNCAYCAY TCNTCNTCNACNAGYACNCCNACNCCNTCNATGAGYTCNAGYCCNGCNACNATGATHAGY AAYCCNCCNTCN---GTNCCNGGNYTNTCNGCNGCNGARTAYGCNACNATHAGYAAYCCN CARCARMGNGCNGCNYTNCARCAYGCNCAYGCNAAYTCNGTNGGNTTYTTYATHACNCAR GAYTCNTCNTTYGGNAAYYTNATHYTNCCNGTNYTNCCNMGNATGCCNGARGTNAARCCN GAYACNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN GGNGTNGARGGNGGNACN---------GGNMGNGGNCCNAAYTCNTCNTCNCCNTCNGCN TCNATGTCNTCNTCNTTYCAYGCNAGYTAYAGY------------------CARCCNAGY CCNGTNMGNATGMGNGARMGNTCNTCNCCNMGNAARCARMGNCCNGCNAGYGTNGGNACN TCNATGCCNAGYTTYGTNGGNGGNGARCCNGCNAARTCNTCNMGNAGYAARAGYTCNGAY MGNATGGCNMGNGAYMGNTCNAARACNMGNCCNAGYMGNMGNAARGAYAAR--------- ------ACNGTNTCNAARGARACNCCNAARGGNAARGARAARAARGARGARACNGARGAY GARAARGAYGGNGGNACNGGNACNGCNAARAARGGNMGNGTNTCNYTNTCNTTYTTYGAY MGNYTNTCNACNCCNAARTTYCAYMGNAARCARGAYGAY------CARAARGAYGCNCCN CCNAARAARGARTCNCCNATHGTNMGNYTNTCNCCNMGNAARGCNTAYTCNACNACNAAY YTNTCNACNATHAARAARAARTCNTCNTTYMGNGAYAAR--------------------- ------ACNAARGCNGAYYTNTCNTCNTCNACNCCNMGNCAYGTNGCNCAYMGNGAYTCN TCNACNTCNTCNCCNMGNACNGCNGGNGGNAGYAGYGTNTCNCCNGCNCCNACNGCNATG TCNAARTCNATHACNGCNTCNCCNMGNATHACNCCNCCNTCNTCNGCNTCNGCNTCNCCN CAYCCNACNGTNACNTCNCAYAGYAAYGCNCCNGCN------------------------ ---CCNAGYTCNGARGAYGGNACNGCNACNCCNMGNGGNGGNACNAAY---CARGAYATH TCNGARGARGCNTAYAARGCNAARATGGCNGARMGNMGNMGNCARGCNMGNGARAARGCN GARMGNGARGCNGARGARGARMGNAARMGNCARGARGARGARMGNYTNGCNGARGARGAR MGNYTNCAYCARGARGARGARGARCARYTNMGNYTNGARGARGARACNATHMGNYTNGCN GARGARGCNMGNAARGCNGARGARGARMGNYTNCARMGNGCNATHGARGCNGARGARAAR MGNAARAARGAYGARGCNGARMGNYTNGARCARGARMGNAARGCNAARGARGARGCNGAR MGNAARGCNMGNGARGARGCNGARMGNATHGARMGNGARAARCARGARAARGCNAARAAR GAYGARGARGARMGNCARGARMGNAARAARAARYTNGARATGATHATGAARMGNGTNAAR ACNGAY------------------CCNGCNCAYGAY------------------AARATG GARAGYCCNGTNMGNTCNTCNGCNAAYTCNCCNAAYMGNAGYGCNYTNGCN--------- ---TCNCCNGARGTNCARGARATGCCNCCNTTYGCNCARGARCARGAYAAYTCNTCNGGN TCNGARGAYGGNAAY------------GGNAARYTNAARGAYCCN------------CCN GTNYTNAGYATGTCNGARAAYGCNMGNGAYTCNGGNAAYTCNTCNGARCCNGCNYTNACN ------------------------------------------------------------ ------------CCNGTNGTNMGNAGYGCNTCNTCNGGNGAYATHATHGAY---AGYACN GCNGARGARGARAARAARGARATGGARAARGGNGAY---------AGYYTNGGNTCNYTN AAYACNCCNGTNAARCCNGCNAAYGGNACNACNTCNACNCCNTCNTCNTCNACNGARGTN AARTCNMGNTTYAARTCNCCNYTNYTNCARCARYTNGTNGARAAYAARGGNGGN---TCN GAYTCNCCNGGNACNCCNAARTTYAARTCNCCNYTNYTNCARAAYYTNYTNGGNAARACN AARGTNGGNGCNMGNATGGGNYTNTCNGCNAGYATGGGNGAYYTNAGYYTNAAYAARGAY ACNGCNGCNACNACNACNACNACNACNATHGGNACNAAYCARCARCARAGYTCNAGYCCN TCNYTNAGYCCNGCNAGYTCNAGYAARGARATHTCNAARGCNGGNCARGAYGARGAYAAR GAYGTNGAYGARTCNGTNGCNTCNTCNTCNTCNATHACNCCNTCNTCNTCNACNTCNAGY CARTCNYTNGAYAGYCAYYTNTCNAAYGGN---GTNGGNAARTCNGAYGGNGARGGNGAR GAYAGYGCNATGACNMGNTCNTCNCCNCCNGGNAGYATGATGATHGAYTCNGCNYTNGGN TCNAGYATHGARCCNCARYTNGARYTNTCNGCNGCNGGN------------TCNGTNATG TCNAAYGGNCAYGGN------AARAAYAARGAYACNATGGGNGAYTCNAGYATHAGYYTN CARTCNCCNGAYGARGARAARACNATHGCNACNTCNGAYCARTAYCAYTAYCARTCNGGN CARTCNTCNTCNCARGARGARACNMGNAGYGAYGGNMGNTTYGARGARYTNATHGAYYTN CCNTAYACNTCNAAYAAYTCNAGYAARGCNAGYGTN------ACNCCNATHATHGCNTTY GARGARAAYAGYYTNMGNACNGCNGAYGTNGGNGARTCNATGTCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNCARGTNYTNGARTCNCARTCNTCNTGGMGN YTNTCNATHATHACNGAYGCNGTNTGGGGNATHATHAAYTTYATHGTNYTNTTYTTYCAR ACNATGTTYAAYCCNAAYAARAAYAGYMGNGGNGARAAYTAYACNTCNGAYTAYMGNMGN CCNGGNGGNGGNGGNCCNCCNAGYMGNMGNATGGGNGGN--------------------- ---YTNTTYCCNMGNAARGGNCARGCNACNATHATGTGYTCNMGNTGYCARAGYCARMGN GAYCCNACNTGYGARATHACNCCNCCNACNCCNACNGCNTGYGTNAGYTCNGGNAGYGGN GTNCCNAARTCNTGYTCNATHGTNMGNGTNTAYAARAARGAYACNGCNATGGAYGCNTTY ATHMGNAGYTGYTCNAGYTCNCARGARACNGGNTGYTTYAAYAGYMGNCCNGGNTAYMGN ACNTGYGCNGARGTNTGYTAYACNGAYGGNTGYAAYTCNGCNTCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTNATHTCNACNYTNTAYCCN AAYACNGTNAAYTCNGARGGNGTNYTNAAYCARATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TTYATHGARTTYATHTAYTAYTGYGTNTAYTGYATHYTNTTYATHATHGCN GCNATHGTNTGYTGYGTNMGNGCNCAYYTNCAYGAYGCNATHGGNGCNTAYGAYYTNGAY TGYTGYGTNGTNGTNACNCARTTYCCNCCNCARACNATGGARAGYGARYTNMGNGCNGTN TTYAARGAYTTYMGNGTNYTNGAYATHTGYGTNYTNAAYAAYGGNTTYCCNGARGGNTGY ACNMGNGCNGTNYTNTAYATGAGYACNATHTAYGARGCNATHCARGCN------------ ------------------------------------ATGTCNAGYGARGARGARGAYTAY ATGTCNGAYACNTTYYTNYTNCARTGYGCNGAYGCNMGNCCNGGNYTNGCNCCNAARCAY AARCARAARCARTAYGARAARGARMGNAARGARAARGARTCNAAYCAYCARAAYAARATG GTNCCNMGNAARCARYTNGARATHCARCARMGNGARGTNGGNYTNACNACNAGYATHTCN GARAARAGYAARGGNTTYTCNYTNYTNCARAARATGGGNTAYAARCCNGGNACNGGNATH GGNAARTCNGGNGARGGNMGNGTNGARCCNGTNGGNTTYGARGTNAARACNGGNMGNGCN GGNYTNGGNAARGARTCNGARATGAARMGNAARTCNTCNGARATGAAYAGYATGMGNGCN GCNATGCARGCNAARMGNAARAARATHCAYGARAARGARACNAARTCNTTYCARAGYMGN ATGAGYGAYAARTTYAGYGAYAARYTNYTNGARAARGAYATGMGNATGGCNCARAARGCN TGYYTNCARYTNGAYCARCARGCNGGNYTNTCNGAYCCNCCNGARCCNTTYTTYTGGCCN CCNAAYAGYYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNMGNCAYAARGCNYTNYTNGTNCAYMGNATG YTNCCNTTYYTNAGYGTNGCNGAYCARMGNGARGTNYTNATGGGNYTNTCNAAYYTNACN TCNAARTGYCCNGAYACNGCNAARCCNYTNGCNYTNGAYACNGGNYTNATHYTNCCNCCN GTNGTNYTNYTNTCNYTNCCNACNGTNMGNTCNTTYAARYTNYTNCCNCCNAGYMGNCAY YTNCARCCNCAYAARYTNCARGGNAGYAGYAGYAGYGGNGGNGAYGGNGTNTTYATHTAY ACNCCNYTNTCNYTNTCNAGYTCNAARGTNGAYGAYAGYMGNCCNGAYTTYAARTGGGTN TGYGAYGAYGTNTGYGARGCNACNYTNCARGTNTCNAAYCCNYTNGTNGAYCCNYTNAAY ATHTCNAARATGGTNYTNACNACNTCNGAYYTNGARACNGARATHTTYCCNGAYAGYTCN GTNATHCCNTCNTCNTCNAARTCNTCNACNGTNAARYTNAARGTNAARCCNAARGARGCN GGNTCNYTNAARGTNCARGGNTAYTCNACNGTNGTNTTYGGNGTNAARAGYAAYTGYMGN YTNMGNGAYYTNACNAGYYTNAARCCNTCNCCNYTNTCNGARATHTCNATHCARGTNGTN CCNMGNYTNCCNCAYYTNGCNYTNACNTGYTCNYTNCCNAARYTNTCNAGYTTYACNACN MGNGGNGGNGGNGCNTAYGTNGTNGCNACNGGNTCNGCNGTNYTNTTYGCNGGNCARAGY GTNGARTGYGTNGTNCAYCARGGNGAYATHGCNACNYTNCCNTGYACNGTNCARTAYYTN GGNGCNMGNCARATHTCNTGGAARAARAGYGGNAGYGARCAYTTYYTNAGYATHGGNACN GAYATHTGGGTNCARGAYGCNAAYYTNGGNATHAARCAYTAYACNTGGCCNGCNGARGTN AGYAAYTGGAAYYTNGARTTYMGNTCNGCNMGNATGGARGAYAGYGGNATHTAYGARTGY CARGTNATHTCNACNGAYAARATGACNTGGTCNGTNGARYTNTCNGTNATHGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TGYYTNATHAARATGTAYACNACNTGYAARGGNGGNTTYYTN GTNTGYCCNMGNTGYAARTGYGTNCAYGGNGARAARGTNGGNAAYTGYCCNGCNGGNTGG ATGMGNTGGGARYTNAARAARYTNTCNYTNCCNGGNCAYGARGAYTGYGGNGGNGCNYTN CARGTNACNTAYAARATHCCNCCNGGNAARCARGCNGARGGNCAYCCNACNCCNGGNAAR CCNTTYACNTCNMGNGGNTTYCCNMGNCCNAAYTAYYTNGAYAAY--------------- ---------------GTNATGATG------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARYTN AGYGCNCARGGNGTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR ACNGTNCCNATHACNGGNCCNATHYTNYTNACNGTNGGNGCNYTNTTYYTNATHYTNGCN TCNMGNCARTTYTTYYTNGCNCAYACNMGNAARAARGARGGNAGYGAYGGNTTYCARGCN CARGAYAARGARATHCAYGARTCNTTYACNTCNYTNMGNCCNAGYGCNAGYGARYTNAGY ATHGAYACNGAYTTYACNGCNCARTGYTAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGAYCAYCARTAYGGNATHGCNGTN ACNAAYAARTTYGCNYTNTTYATHGAYGARGGNGAYGAYCCNTTYGARGCNGTNTCN--- ---------------AARAAYAARGCNAARAARGAYGCNGAYAARAAR---CCNAARAAY AARGTNAARAARAAYYTNCCNGCNGARGAYAARCCNTCNGCNCCNGARGARGGNGCNAAR AARAARGAR---------GTNGGNGAYAARCCNCARMGNCARACNGARMGNGGNAARGGN AGYGCNMGNAAYMGNGARCCNMGNGARYTNMGNGARAAYGAYGGNGAYAARMGNYTNCCN MGNMGNCARGGN------------------------------------------------ ------ACNMGNGARAAYAARGAYGGNAARYTNGGNGAYGARAAYGTNCCNCCNGARTTY MGNGARMGNCCN---GARGGNGGNTTYAARMGNMGNGAR---------GAYMGNGARGGN GGNTTYGGNGGNGARMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNGGNMGNGGN GGNGARMGNGGNGGNAGYAGYAGY---GGN------TTYGGNTCNMGN------GGNGAY MGNAARMGNGARTTYGAYMGNCAYAGYGGNACNGAYMGNACNGGNATHAARCCNATHGAR AARAARGARGGNGGNGGNGCNCAYAAYTGGGGNAGYTTYMGNGAYGAYATHGARGARCAR GGNCARGTNAAYGTNTCNGARGARTCNAAYGARTGGGGNAAYCAR------------CCN GAYAARCCNGARYTNAAYGARAGYGGNGARGCNGARAAYATHACNGARGARGARGCNCAR CCNCARCARATGACNYTNGAYGARTGGAARGCNYTNCARACN---CARAGYAARCCNAAR CCNGARTTYAAYACNMGNCARGCNGGNGARGGNGTNGAYTCNGCNCARTGGAARAARGGN GTNGARTAYCARAARAAR------GTNGARGARGARGAYCARGARGARGGNGARTAYGAR GARGGNGAYCAYAGYGAYCAYCAYACNMGNAAYAGYAARCARYTNGTNACNGAYATHMGN ATHACNTTYAAYGAYAAYCCNMGNMGNGGNMGNGGNMGN---MGNGGNGGNMGNGGNGGN ATGGARMGNGGNGGNGGNGGNGCNGGNMGNGGNGCNGGNMGN---------------GGN AGYYTNMGNGGNTTYAGYAAYAAR---AARGARACNGCNCCNMGNTTYGAYGAYGARTCN GAYTTYCCNTCNYTNYTNAARACNGCNGCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TAYTTYATHTCNATHCCNTAYGARGARTGYAARAARMGN MGNTGYTCNMGNAAYTAYGCNGTNCCNGAYCCNCCNGGNYTNTTYGAYGGNCAYGTNTGG CCNATGTAYGTNAARCAYACNAARATGATGGARGAYGGNGTNGAYGTNGTNGCNYTNGAY GGNACNAARTCNAARGARCARYTNTTYAAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNCAYGTNMGNTAYAARAAYAAYAARCARMGNGTNAARGARGCNAARATHCAR GTNGAYAARAGYAARAARTTYATHTCNAARMGNGARAARAARAARTCNCARTTY---TCN GGNAAYAAYCARGARGAYAARAGYACNATHATHGCNGARAARCCNGTNGAYAAYGTNTGG GTNMGNAARTTYTAYCCNAAYCCNMGNTTYTCNATHGARGARGCNYTNAAYMGNCAYCAR GCNTTYGCNCARCCNGCNATGYTNGAYAAYGTNAAYGGNYTNGTNTAYYTNGAYATGYTN YTNGAYTTYAGYACNAARAARCARACNAARTTYYTNAARAAYATHMGNTCNACNYTNYTN YTNCCNCAYCCNTTYAAYTGGGGNAARCCNCCNTCNATHYTNGTNTTYTCNAARGARGAR GARYTNACNAAYYTNGCNYTNTCNYTNGGNGCNAARCAYGCNGGNTCNCCNACNGARGTN ATHAARATGATHGARAAYGGNATHYTNAAYCCNAARGAYTTYACNCAYGTNYTNGCNACN GCNGAYTGYGCNGCNGAYATHACNCCNGCNMGNTCNTAYTTYMGNGAYAARTTYCCNCAR MGNGCNAARGGNAAYYTNGGNACNGAYYTNAAYACNATGTGGACNYTNTTYCAYACNGGN TAYACNTAYGARTCNCARAGYYTNACNAAYGCNCARGGNAARYTNCARGTNCCNYTNGGN CARYTNAARCARCCNACNAGYCAYATHGTNGCNAAYTTYGARGCNTAYATHGARTCNATH TGYAARCAYAARAGYATHGCNYTNGGNCCNTTYATHCARTCNATGAAYGTNGTNGCNCCN CCNTCNCCNGARGARTTYATHGTNAARGTNGARGARTAYGTNCCNGGNAAYAARAAYGAR GARGTNGAYTCNGAYGAYGARGAY------------------------------------ ---------------CCNGCNGGNACNATHTTYCARGTNCARGCNACNCAYMGNTAYCAR GGNGARGAYGTNGAYGARYTNAAYTTYGARCCNGGNGARGTNATHTAYGTNATHGARTTY GARTGYCCNGAYGARCARGAYGAYGGNTGGYTNATGGGNGTNAARCARTCNGAYGGNATH AARGGNGTNTTYCCNGARAAYTTYACNMGNAARATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CARGGNMGNGCNGARATGGAYYTNAARCAYGARGCNTCN CCNTAYCCNAAYATHTCNYTNTGYMGNGCNMGNYTNGAYATHCCNTAYGGNACNCAYCAY ACNAARATGATGTTYYTNYTNTAYAARTCNGGNYTNMGNGTNGTNATHCAYACNGCNAAY YTNATHCCNAAYGAYTGGCAYCARAARACNCARGGNATHTGGATHAGYCCNATHTTYCCN CCNYTN---AGYCCN---TCNGAYYTNGGNGARTCNMGNACNAARTTYAARGCNGARYTN YTNMGNTAYGTNTCNGCNTAYAARTCNCCNAARYTNACNCCNTGGGARAARATHATHTCN CARCAYGAYATGTCNTCNGCNAAYGTNCAYATHGTNGCNTCNATHCCNGGNMGNCAYGTN ATGAAYGAYAARCAYYTNTGGGGNCAYYTNMGNGTNAARAARATHYTNTCNACNACNGGN CCNGAYCARAGYYTNGTNAARAAYTGGCCNGTNATHGGNCARTTYTCNAGYATHGGNTCN YTNGGNGCNAAYCCNGAYGCNTGGYTNYTNAAYGARTGGGGNCARTCNATGGCNGARTGY AARAARACNATGTCNGCNATHATHCCNGCNTCNAARYTNMGNYTNATHTTYCCNTCNAAR GAYAAYATHMGNYTNAGYYTNGARGGNTAYAAYGGNGGNGGNTGYGTNCCNTAYTCNATH AARACNGCNTCNAARCARCCNTGGYTNACNCCNTTYTTYTGYCARTGGAARTCNGARGGN MGNGGNMGNTCNAAYGCNGTNCCNCAYATHAARACNTAYACNMGNTCNTCNCCNGAYGGN TCNGARGCNGCNTGGTTYATGGTNACNAGYGCNAAYYTNTCNAARGCNGCNTGGGGNTCN YTNGARAARAARGGNGGNCARYTNATGATHMGNTCNTAYGARATHGGNGTNYTNTTYYTN CCNGCNGAYTTYGGNTGYAARAAYTCNTTYAARGTNAGYAGYCAYACNGAYCARGTNACN GAYTCNGAYGCNAARGTNTTYCCNYTNCCNTTYGAYYTNCCNCCNACNACNTAYATHAAR GGNTCNAARAARTCNGTNGARYTNTTYTAYGAYGTNGTNTCNCCNTAYTCNTGGTTYGCN TTYGARGTNATGATHMGNTAYCARAAYMGNTGGAAYATHAAYYTNAARYTNMGNCCNTTY TTYYTNGGNGGNATHATGCARGCNTCNGGNAAYMGNCCNCCNGCNATGGTNCCNAAYAAR GGNATHCAYAGYACNATHGAYGTNGARMGNTGYGCNAARTAYTTYGARGTNCCNYTNGTN ATHCCNAARAAYCCNYTNGARYTNATGTTYGARAARGGNTCNYTNAARGCNCARMGNTTY YTNACNGCNYTNGAYYTNAARTAYCCNGARAARGTNGARGCNGTNTCNMGNGARTTYTGG ATGMGNGGNTGGTGYMGNGAYGARGAYYTNTCNGAYGAYTCNAGYYTNGCNGARGCNGCN AAYAARGCNGGNYTNAGYCARAARGAYATHCARGARYTNYTNTCNTGYYTNAARGAYTCN CAYGTNAARGAYMGNYTNAARAARACNACNGAYGARGCNTAYGARYTNGGNGCNTTYGGN TCNCCNATGATHGTNACNGAYGTNAAYGGNAARAARGARTGGGTNTTYGGNAGYGAYMGN TTYCCNATHYTNGCNCARATGYTNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATHATHTGYGGNTTYTGYATHTTYGGNGGN GTNATHTCNTTYTGYGGNGAYATHATHGTNGCNGCNAARTAYAARTCNGTNCARGAYYTN TTYAARGGNGARMGNYTNTCNTCNGCNGCNAARAGYYTNYTNGGNAAYGARTTYACNYTN AGYTGGGGNTTYGGNYTNGAYATHYTNTCNGTNATHTTYGCNTGYYTNGGNGGNGCNYTN CAYYTNGTNGCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARMGNGGNACNATH GAYTAYATHCAYTAYGCNGCNGGNTGYAAYGAYCARGTNCCNTCNTAYTGGACNTGYAAR GCNGGNAAYAARAAYGAYAAYTCNAGYTAYYTNGTNAGYGTNGAYGARCAYACNTCNAAY GCNGTNGCNAARYTNGTNYTNGCNTGYTGGGAYCARYTNCARGTNGGNAARGGNGCNGAY GCNGCNAAYATHCCNGCNAAYTCNACNATHAARGTNGTNAARGTNCARMGNYTNGARAAY CCNTCNYTNTTYYTNGGNTAYTCNATGAARMGNAARGTNATHTTYAARTCNATGGARYTN AARAAYMGNYTNTGYACNAGYATHMGNAAYYTNAAR---AAYAGYAARGGNCCNGCNYTN ACNATGAARAAYGCNCCNGGNTTYYTNAARAARCAR---YTNTGYCAYGARATHAAYGAR YTNTAYYTNTTYCAYGGNACNAARCARGAYATHGTNGAYTCNATHTGYAAYCARGGNATG GAYAAYMGNYTNTCNAAYCCNGGNGCNATGTTYGGNCARGGNGTNTAYATGGCNGARAGY TCNACNAARTCNGAYCARTAYGCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------MGNGTNYTNAAYGARYTNAAR ATGGARATGGCNAAYGTNMGNGAYGAYTCNMGNCCNGCNTTYCCNMGNCCNACNAAYTGY ATHGGNYTNTAYYTNGAYGCNATHGAYGCNMGNCCNGARAARACNACNACNGTNGGNTCN CAYCAYGCNTTYATGATGGGNGTNATGGAYMGNYTNCARGARTAYYTNMGNGGNYTNGAY YTNTCNAARGTNAARGGNGGNYTNGARACNMGNCAYGTNGGNGAYGGNGTNATHYTNGAR GGNATHAARCAYAGYTGYATHATHGCNYTNAARTTYGAYGAYGTNATHGCNYTNGAYGAY YTNTGGACNATHTAYAARMGNAAYAARYTNACNCARGCNTTYCARGAYATHYTNGTNGAY MGNACNYTNYTNMGNTTYGTNAAYTGYGCNAARYTNACNYTNMGNGTNAARYTNTGGGAR GAYGARGTNAARGGNTGYAARGARGAYYTNMGNMGNMGNTCNAGYGAYMGNGTNAARYTN TCNAGYYTNGARMGNGAYTTYTCNATHGTNAARMGNGTNCARGARTTYCARAARACNATG CCNGARAARGTNGCNAARGCNMGNGAYGTNGARAAYCARTTYGARCAYAARYTNGGNGAR TTYATGATGACNATHAARCARATHYTNCCNCARAAYGCNCARGTNATHAARACNATHAAR GARTTYCAYACNAAYYTNAARATGGCNMGNGGNGTNAARAARGTNAGYTTYGARAAYATH GAYCAYTAYYTNCAYTCNYTNGARTTYTTYMGNAARATHTTYCARGARGTNGARAARGAR ATHGTNCAYCCNYTNTGYCARGTNCARGGNATHTGYGARAAYGARAARCARMGNAAYYTN AARAARACNATHAARAARGCNTCNGCNGARATGYTNGGNTAYYTNAARCCNGARGTNGAY YTNCARAARGTNMGNCAYAARGARTGGGARGGNAARGTNYTNCCNMGNGARCARGGNYTN TTYTAYGGNYTNATHAGYYTNATHCCNATGAGYGTNGAYMGNYTNACNACNATHGAYTAY AGYACNGAYGARTAYATHAAYGAYTTYCCNGARATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TGGGAR GAYGGNGARGTNCARTCNTCNCAYAGYGARGGNTCNAAYAARGARGAYAGYGAYTCNGAY GAYTAYGGNAAY---CCNTCNGARACNGGNTCNATHAAYTCNGAYAARGARGAYTGGAAR TCNCARTCNTCNAARMGNAARAARAARCAYAARCAYAARCAYAARAARAARAARAARAAR AARTCNAGYAARGARAARGARCAYYTNAARGGNAARAARGARMGNGARAARGAYAARGAY AARMGNAAYAARAARGARMGNGARCARTCNTCNAGYGCNATHTCN--------------- AGYCAYAARGAYYTNGARAAYGTNGAYMGNGAYAARAARAAYGAYGARAARGTNAARMGN MGNGAYTAYTCNGAYAGYAGYAAYGARAARTCNMGNGGNAARGGNAGYGAYTCNGARAGY CCNAARAARGARAGYAARTCNGCNGAYMGNGARAARTCNGAYAGYAAR------------ ---------------------AARMGNGARAARGARAARAARMGNAARCAYGARMGNTCN MGNTCNMGNACNCCNAARMGNTCNAARAARTCNMGNTCNMGNTCNAARTCN--------- CCNMGNAARACNGCNAGYCCNAARMGNAGYMGNTAYAGYGARTGGGAYGCNMGNMGNTAY AGYGAYGAYTCNAARAARYTNYTNMGNTCNMGNTCNGAYMGNTCNAARGAR------MGN GGNMGNGAR---CARGAYMGNGAYYTNMGNYTNCARATHGAYAARGCNAARYTNMGNAAR ATHGCNATHGCNAAYGCNYTNAAYAGYATGAARTCNGGNCARCARGTNCCNATHCARYTN GAYGTNGCNGCNGTNAARTCNGGNGGNAARTCNGTNGARGARYTNACNGAYTTYTGYAAR MGNATHTCNGARAARGARCARGARAARCARGAYAAYGCNATHAGYGAYAGYAGYGARGAR GARACNGCNCARACNGAYGARGARGARCCNYTNATHCAYCAYCCNTTYAARGTNAARGAR GCNTCNTCNAAYATHGTNATGAAYATHMGNAAYGCNAARCARYTNCCNGTNYTNACNCCN TCNGARAARCARGCNCARCARGCNACNYTNMGNYTNGCNTAYCCNGTNTCNAGYGGNTCN CAYCAYMGNGCNAGYGARTCNGARTGGGTNCCNGTNGARAARACNACNGCNCARACNACN AAYACNATHAGYMGNGTNYTNGAYTCNCARGCNTCNACNGARTCNCARCCN------GAR CCNTCNCAR---------AGYGTNTTYCCNAGYGCNCCNCARAAYGTNGAYATHGGNGCN ATHATHACNGARMGNYTNCARGCNGTNMGNAARYTNCARGCNAAYCCNTAYGAYGTNCAR GCNYTNAGYTCNATGCAYAARGTNCARGARAARGCNAGYCARTGGGCNCARTCNAARCAY YTNCCNGGNCARTTYGTNGGNAGYACNGGNGCNCARGTNATGTCNCARGARCARATHATG GGNGAYAARMGNMGNCARGCNTGGGTNAARAAR------------------------GTN GCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------ACNMGNGARYTNACNCAYGGNCARCAYACN GCNAGYGCNYTNACNCARCCNCARGCNAARGAYYTNAARCAYCCNGTNTCNGCNYTNATG GARYTNTGYAAYAARMGNMGNTGGGGNCCNCCNTGYTTYACNGTNGTNTCNGARAAYGGN CCNGAYCAYAARAARTGYTTYYTNTTYAARGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARGTNGGNGTNGAYGGNGARGTN YTNGTNATHCAYAAYGTNACNMGNTAYTGYGGNGGNAAYTAYCARTGYGTNGCNTAYAAY GGNGTNAGYCCNGCNGCNACNMGNGTNATHGAYGTNTCN--------------------- ------------------------------------------------------------ ------------------------------------------ACNGARTCNGGNATHGGN AARGARTTYTAYGTNMGNGAYCARTCNGCNACNATHTGYTGYATHTTYTAYGARATHGAY MGNGARATGCCNCARYTNATGAARGGNCARGTNCAYMGNYTNGTNGGNTCNATGCAYAAR MGNCARGAYAGYTTYAARGTNGTNTCNATGMGNAARGCNGAYAARGARGARMGNTCNAGY TGYCARAARGCNACNGARGTNTCNYTNCAYGARATGGAYAARYTNGCN---CCNGGNYTN AAYCCNTCNAAYTTYGGNMGNAAYAAYYTNCCNACNATHAARGGNATHATGGTNATHACN GCNGCNGARGGNGTNAAYGARAGYCARTCNATHTTYGGNCAYAAYTGGYTNAARTCNACN ACNTTYTCNYTNGGNTTYGAYATGAARATGTCNGARYTNATGTAYAARAARAGYATHTAY AARACNGARTTYAARTGYGTNATGTCNTGYGTNTAYGTNGGNMGNTCNTCNYTNMGNYTN YTNGCNAARTTYTTYATHGARGAYCAYCCNGARCCNGTNATHAGYTAYTAYCAYTTYATH GTNAGYGTNAAYTTYTAYACNMGNAARGCNACNTCNTTYCCNTCNTGGATGGCNGAYATH GTNAARGGNMGNGARTGYTCNGAYCARGARCCNMGNATHAARCARYTNAAYMGNCCNCAR GAYACNTTYGTNCAYAGYGTNTAYGTNACNTGGTCNAAYACNGAYGTNAAYCAYCAYTGY AAYTTYTCNAAYTAYCCNAAYTTYGTNGTNGAYGCNACNCAYGCNGCNYTNMGNATHAAR GCNGGNAAYAGYYTNCCNTGYCAY---AARATHGAYGCNTCNAARGTNTGYMGNGGNGAY CCNTCNGCNYTNAARGGNYTNACNAARGARATHGTNGGNTGYGGNGTNAARGAYGTNAAR GTNCAYTTYTTYAARGARTGYGTNGARGAYGAYYTNYTNGAYATHCAYATHTGGCARGAY GGNGTNAARAAYAAYGTNYTNTTYTCNTCNGTNGARAARAAYAAYGCNGTNCARATHATH ATGGARTAYTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNGTNGTNCARGCNGARGARYTNGGNTGY GARGGNAARGTNGARGARGCNCARGGNGTNATGAARYTNGTNGAYCARYTNAARGARGAR MGNCAYCARYTNGARATG---AAR---CCNATGCARGAYGAYGGNGGNCCNYTNATGAAR CARATGGARGTNTGYGAYGTNTGYGGNGCNTTYYTNATHGTNGGNGAYGCNCCNCARMGN CARGAYGARCAYYTNATGGGNAARCARCAYGCNGGNTAYGCNCARGTNMGNGCNGARATH GAYAARMGNAARAARAARGTNMGNGAYGARACNGAYGCNMGNGARGCNAAYGARAAYMGN YTNMGNYTNGARMGNGARGARMGNGARAARGARMGNCARMGNGARMGNGAYGARMGNMGN CARMGNGARMGNGAYGTNGARMGNMGNMGNGARMGNGAYMGNGAYAARMGNMGNMGNAGY MGNTCNMGNAGYMGNGAYMGNGGNAARGAYMGNMGNMGNTCNMGNAGYMGNGAYMGNMGN MGNCARMGNAGYTCNAGYMGNGAYMGNMGNAGYMGNMGNAGYMGNAGYMGNAAYMGNGAY MGNMGNMGN---------AGYTCNAGYMGNGGNAARMGNTCNMGNMGNTCNTCNAGYMGN GARMGNAARCARGAYMGNMGNMGNTCNAGYGAYMGNAARTCNMGNAGYMGNGCNMGNTCN GGNTCNMGNGARMGNAARGARMGNAGYAARGAR------------AARGARMGNAAYGAR GCNMGNGARGAYATGAARACNAAYTGYMGNGARAGY------------AAYTCNATHCAY CCNGARACNATGGTNACNGAYTGYACNGAYGARTTYGTNAAYYTNATHTCNCARCAYYTN AAYGGNAARGGNTGYAAYAAYTGGMGNAAYYTNYTNGGNYTNTAYAAYTGGAAYTAYAAY AARYTNAAYYTNTTYGARAGYMGNCAYCAYCCNGGNGGNTAYTTYTGYAGYATHYTNGGN GAR--------------------------------------------------------- ------------------------------------------------ATGGAYTTYGAY TCNTCNTCNAARTTYATHGCNTCNYTNGCNMGNTTYYTNCARTCNYTNTGYAAYGGNTAY GTNGARTTYGAYAARGGNGTNGARGTNATHGGNCAYATHTAYYTNAGYGTNGAYAGYGAY ACNGGNMGNAARATHGAYTAYGTNYTNAAYGARAARGTNTGYAARAAYGAYAAYTCNGTN ACNTTYATHAGYAAYAGYTTYCAYGCNCARCCNGCNGARAARCCNCARCCNGTNCCNAAR AARCCNGARACNGAYAAYMGNAAYGARGAYTCNATH------GAYGARTCNGGNCARTCN GTNCCNAAYAAYGTNAAYATHMGNACNACNGAYTCNTCNMGN------------------ GAYAGYCCNYTNTCNTCNAAYAARMGNCCNMGNTCNCCNYTNCARTGYMGNATGGGNATH GGNMGNGGNTCNYTNGGNCCNGTNGCNAARTCNCCNMGNTAYCARGAYCARACNGGNGTN AARTTYAGYCAYCAYACNGAYGTNTCNACNAAYAAYGTNATG---AAYAGYAGYGARGAY TAYGAYGGNTCNTAY------------GGNGARGAYGARGAY------------AGYTTY YTNAAYCARGAY---TAYTCNAAYYTNGARATHGAYCARAARCCNGTNATHGARCCNGAY GTNAGYATHGTNAARGARGARTAYATGGCNAGYCARCARGGNGGNGCNTCNTAYTCN--- AAYAGYCARCCNACNGGNCCNGGNMGN---GGNMGNCCNCCNAGYTCNTCN--------- ------------------CARGCNTCNTTYCCNACNCAYCAYAAYTCNACNTTYACNTCN TCNAAYTAYTCNGCNTCNTCNYTNATGTCNCAYGAYCCNCCNAARYTNACNCARGCNCAR CARGARGARYTNGARATGTAYTAYMGNAARGGNACNGAYCARCAYYTNACNTTYYTNMGN AAYATGMGNGARGCNCAYGCNATGTAYCCNTTYACNGGNAARMGNGAYAARGARYTNTTY GAYAARGCNYTNGARGARYTNTTYYTNMGNATGCCNATHYTN------------------ ------------YTNTAYCAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNCCNYTNGTNAAYTCNGARTTYTAYACNGGNTGGYTN GAYCAYTGGGGNCAYCCNCAYTCNAARACNAGYACNGTNMGNGTNAGYAARAGYYTNGAY ATHYTNYTNGGNTAYAAY---GCNAAYATHAAYATGTAYATGTTYGTNGGNGGNACNAAY TTYGGNTAYTAYAAYGGNGCNAAYCARCCNCCNTAYGARGCNGTNCCNACNTCNTAYGAY TAYAAYGCNCCNATHACNGARGCNGGNGAYATHGTNCCNAARTTYTAYGCNATHMGNGAY GTNGTNTCNAARTAYYTNCCNYTNCCNCCNTCNCCNATHCCNTCNAAYACNACNAARATG AAYTAYGGNTCNYTNCCNYTNAGYTTYYTNTGYACNGTNCARGAYGCNYTNACNGTNYTN ACNCCNGARGGNCCNGCNCAYACNAARTAYCCNGTNTCNATGGARCARYTNAARTTYTAY GARGGNTTYATHYTNTAYMGNCAYYTNYTNAARACNAAYTAYTCNAARCCNGTNGARYTN TAYACNMGNGARACNMGNGAYMGNGCNATGGTNATGGTNAAYGGNGTNCCNYTNGGNATH YTNGAYMGNAARACNAAYACNACNGTNAAYATHACNGGNACNATGTAYCARTAYYTNGAY ATHYTNGTNGARAAYCARGGNMGNGTNGGNTTY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARGCNCARMGNCARAARGARAARGCNGARAARGARMGNAARGARAARGAR---YTNGCN GCNAARCARGARTCNGAR------ATHCCNAGYGAYGAYGARGARCCNTCNCARGARATG GAYGCNGGNGAYTTYGCNATHGAYYTNGGNATHGCNTGYGTNGTNTGYMGNCARTTYGAY GTNAGYTCNGGNAAYCARYTNGTNGARTGYCARGARTGYCAYAGYYTNTAYCAYCARGAR TGYCAYAARCCNACNGTNACNGGNCARGAYGTNAGYGAYCCNMGNTTYGTNTGGTAYTGY TCNMGNTGYACNAARAGYTTYAARAARATGATGACNCARAARCCNGTNAAR---CCN--- AARCCNTCNYTNCCNYTNTCNTCNACNTCNAARGARACNACNTCNACNATHGCNAARACN AAYAARTCNGARTCNGAYTCNGGNAGYCARGCNTTYMGNMGNATHGAYCCNAARACNATH GTNACNCCNAARGAYCCNAGYAGYYTNATGTCNTCNTCNAARGCNATGGTNGGNYTNGCN GGNYTNGCNGCNAAYYTNACNAARCCNMGNGGNGARTCNAARGCNGGNCCNGTNTCNAAR AARAAYGAYTCNAARGGNGAYGCNGTNAARYTNTCNAARGGNGAY--------------- ------------GGNTCNAARTCNTCNAGYAARTCNGAYACNAARTCN------ACNGCN TCNAARCARGAYAGYTCNACNAARCARTCNCCNTCNTCNTCNAARAGY------------ ---GAYGCNMGNAARTCNGAYGCNACNAARTCNTCNTCNAGYAARGARGARTCNAARGAR GGNAARAARTCNTCNGARTCNAARAGYAARTCNGAYGAYMGNMGNACNAGYGARAGYTCN TCNMGNAARGARGAYAARAARGAYAARTCNTCNAARTCNTCNTCNAARGARGAYAARAAR TCNGAYAARTCNTCNCCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AGYATHCCNAARATHACNMGNGCNCCNATGGAYCAYAARGTNGGNGAR GGNGGNACNGTNAGYTTYTTYTGYMGNGCNTCNGGNAAYCCNACNCCNACNTTYCARTGG GARMGNGAYGGNAARMGNATHMGNGCNMGNMGNAARCAYTTYGARATHCAYGARGARCCN CAYATGTCNGGNYTNMGNATHCARCAYGCNAAYGCNAARAARGAYAAYGCNACNTTYACN TGYYTNGCNACNAAYAAYYTN--------------------------------------- ---------GTNTTYCARGCNGCNGTNACNGCNGCNACNAAYGGNTCNAARGTNGTNCAY ATHTGYACNCAYCCNATHTCNAARYTNCCNACNCCNGTNCAYGGNATGTCNAGYCCNGAR CCNTCNGTNATGAARAAYGTNGAYTTYYTNTAYTTYGARGARACNGCNGARYTNATHGCN TAYTTYGCNGGNATHCAYATGAARAARAARYTNCCNAGYTAYATHATHGTNGARGAYATH YTNTCNTAYGCNTCNCARMGNCARGAYAARCCNGTNGARMGNACNYTNGCNAARYTNYTN GCNYTNATHTCNGAYGCNAGYACNTGGATHGCNAAYCAYAAYGAYATHGGNAARTGYAAY GTNYTNYTNACNGCNCCNTCNMGNATHAARYTNATGCARAAYATHYTNAARCARTTYGAY TAYGARATHGCNATHTAYGARGGNCCNACNAARGARAGYGTNTTYTCNAARYTNTCNTTY ACNTGYAAYAARTCNCARATHTCNYTNAGYTTYCARAAYCARAARGAYTGYATHACNYTN AAYGAYGTNAGYGTNACNATGAARGARAARATHAAYAARGARYTNATHCARATHAARACN GCNGAYGARAARGARYTNCARMGNMGNATHGAYTCNTTYATHMGNAAYAARMGNAAYGAR GTNAAYGARMGNAAYATHMGNGARTTYATHTCNCCNTTYGGNTCNGAYCCNAAYGAYAGY TGYGCNMGNGTNGAYGCNGTNTAYATHCAYMGNGARGGNATGAARAGYCAYATHAAYYTN AARAAYGTNGARAAYGCNTAYGGNCCNCARACNMGNYTNMGNTCNAAYGTNAGYGAYGAR GCNMGNCCNTGGATGGTNGCNGCNGAYATGCARMGNGCNGARGCNGTNGARGARMGNYTN TCNAAYATGGARCAYCAYYTNAAYATHACNGAYGAYGGNGGNGAYATHTAYAARMGNATH AARTCNYTNGARGAYMGNATHAGYTTYYTNGARGGNGTNTCNCCNGARTAYTTYACNAAY GGNATHCCNCCNAARAARATHCAYAARTCNAARCAY---------------------ATH GTNCCNACNAARCARACNGCNGCNGARGTNTCNGGNCAYCCNACNGAYATHATHGTNAAY AARTTYGARGAYCAYYTNTTYATHATHATHACNCARTAYCARAARATHGGNACNGTNGTN GARGTNTCNMGNGAYGTNGTNAGYGAYGARGTNCARGGNCCNATHCCNATGTTYTCNACN AAYGTNYTNYTNGGNAARGAYGARCCNYTNATGCAYGTNATHGCNAARACNATHGTNACN GCNYTNAAYCCNCCNATHCCNGTNATHYTNTCNYTNGCNYTNAARGARACNTCNCAYGAY TCNGTNCARGCNATHATHGARATHATHAARTCNTGYYTNATGGCNACNAAYCAYCAYTTY GARGCNMGNMGNMGNCARATGGTNYTNGAYAARGCNTGYAARGCNMGNAARGARATGGCN TAYAARTCNGCNGAYGGN------GCNGCNCCNTCNTCNGARGAYGCNATGAARCCNGAR ACNATHATGTGYACNGAYCCNGGNCARTTYTAYCARACNMGNCCNAGYATHCAYGTNTGG ACNGGNCCNGARMGNAAYMGNMGNACNTAYGAYMGNAGYMGNGARGGNCCNATHYTNGGN AGYTCNTGGMGNCARYTNGARAARGARATGAAYTTYMGNCARAAYAGYYTNAGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGCCNAAR TTYTAYGARGAYGTNGARGARAARAGYACNCARCCNMGNYTNGCNTGYGARGGNATHMGN GAYGAYYTNYTNGARTGYYTNYTNAARAGYGAYTGYTGYAARAARGARAARAARACNCCN MGNGARTGYATG---------AGYMGNGTNGGNGAYCCNTCNGTNCCNGAYGARTGYTAY AARYTNMGNATHGCNTTYTTYGAYTGYMGNMGNTCNATHYTNGAYATGMGNACNMGNTTY MGNGGNMGNAARGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARGAYAARTCNAARAARAAYGCNATHCARGCNAARATHAAYMGNGARAARAARAARGCN TAYATHAARAGYYTNGARGAYGARATHCARTCNYTNAARACNGARAAYMGNAARYTNAAR TCNGARAAYTCNAARATGCAYAAYACNACNTCNGAYYTNGARGARGARGTNGCNTAYYTN AARTCNGTNYTNGTNAAYTCNAGYTCNYTNTCNAAYGTNYTNAARAAYATHTCNGGNGTN AAYGARGTNAARYTNTCNGCNACNATHGTNAGYMGNAARMGNGCNAGY---------GAY GAYCAYAGYTAYAAYATHGTNGARAGYAGYCCNGARAARMGNGCNMGNMGNATHAAYGAR AAYYTNAARAARGCNGGNGTNTGYYTNCAYGTNAAYGGNGAYTCNGCNTGYYTNGARTTY TGYGCNCAYTGYTCNAARYTNGCNCARAARTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYGAYATHACNAARMGNGTNAARGARATGGGNGAR YTNTTYTGYCARCAYTAYATHAARTCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ACNTCNTAYGGNGGNCAYGTNGAYCAYAGYAGYAARGGNGGNACNAGYTAYGGN GTNCAYGGNAGYCAYAGYTGGTCNCAYTCNGGNGGNAGYAARACNACNGTNTCNGGNGGN TTYACNCAYAAYTCNCAYGGNGGNAAYAGYGCNGGNATHAGYGTNAGYCAYACN------ ---------------AAYAARTGYTTYGTNGCNGTNCAYTCNGGNGCNGGNAAYCAYTCN AARTCNAAYGARAAYCAYAAYAARGAYATHTGYAARGCNGCNTGYYTNCARGCNATGGAR YTNYTNAARTCNAARAARTCNGCNATHGAYGCNGTNACNACNGCNGTNATGACNYTNGAR GAYAAYGARAGYACNAAYGCNGGNTAYGGNTCNAAYYTNAAYGTNCARGGNAGYGTNGAR TGYGARGCNTGYGCNATGGAYGGNACNTCNYTNTAYTTYGGNGGNGTNGGNGCNYTNTCN GGNGTNAARAAYCCNGTNAARGTNGCNAAYATHYTNGTNAARGARCARATHGARGGNCCN YTNCCNTTYGGNMGNGTNMGNCCNAGYATHYTNGTNGGNAARGGNGCNAARACNTTYTGY ATGGAYCAYGAYATHGAYACNAAYTAYAAYATGATHTCNAARTCNGCNTTYAARACNTAY AAYMGNTAYAARMGNAARTGYMGN------------------------------------ ---YTNACNGAYTCNAAYACN------AARMGNMGNAARGTNGARCCN------------ ---GCNGARAAYTTYCCNACNCCNTCNGAR------------------------------ TCNATHCARGAYACNGTNGGNGCNATHTGYGTNGAYCARGARGGNAAYGTNGCNGCNGCN TCNTCNAGYGGNGGNATHTGGYTNAARCAYCCNGGNMGNYTNGGNCCNATHGCNATGTAY GGNGCNGGNTGYTGGGCNCARAAYCARGCNTCNGCNAGYAARCCNGGNGTNGCNGTNGTN ACNTCNGGNTGYGGNGARCAYATHATGCARACNGTNYTNGCNAARACNTGYGCNGAYGGN ATHMGNTCNTCNGARAAYYTNTCNCARTCNYTNCCNMGNGTNTTYAAYAAYGAYTTYYTN GARTCNGARTTYYTNTCNACNAARCCNGARAARYTNAGYGGNGTNYTNGCNYTNAARTTY AGYGARACNTCNGAYGGNAARGARGTNGARYTNGGNTGGATHCAYTCNACNAAYAGYTTY TGYTTYGCNTTYATGGGNGGNGAYCARAARACNCCNAARGCNYTNATGTCNTAYYTNGAR GARCARTGYATHCCNGGNCAYTCNTTYACNATGGGNGGNCAYYTNGTNTTYYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARGCNAAYCCNGCNGTNMGNTTYYTNYTNAGYAGYGCNACNGGNATHYTNTTY GGNATHGCNATHGARAARGGNMGNGTNTTYGAYCCNCARGTNATHMGNGAYCARATGYTN TTYAARMGNTTYACNATGYTNAARATGTTYYTNTCNGCNACNGCNATHGGNYTNYTNTGY TTYTCNYTNATGAGYTCNYTNCCNCARTCNATGMGNAARYTNACNATHGCNYTNCARMGN TTYATHGARGCNCCNCCNGCNAARAGYGTNTTYGGNGTNTTYACNGGNGCNYTNYTNYTN GGNAGYGGNATGGCNATHGCNGGNGCNTGYCCNGGNGTNGTNYTNGTNCARATHGGNACN GGNGTNTCNAGYGCNTGGATHACNGTNGCNGGNGGNYTNYTNGGNGCNYTNTCNTAYGCN TTYATHTCNTCNAGYYTNCCNAGYGTNTTYATHCARAARACNAARTTYAARTTYCAYTAY YTNAAYTAYTAYYTNGAYATHCCNTAYGTNTCNATHGCNGTNCCNTTYTCNTGYACNATG GCNGCNGCNGTNATGGGNYTNGARYTNTAYTCNCCNTGGTAYACNGARGTNGAYGARTCN YTNYTNACNGAYGGNGTNATGAAYGCNGGNGCNTGGCCNCCNTTYATHGCNGGNGTNTTY ATHGGNGCNYTNCARYTNCCNACNGTNYTNGTNAAYGARGAYACNYTNGGNTCNTCNTCN AGYTAYGTNACNATHGTNTCNAARATHCCNTCNYTNYTNCAY---------GGNGAYATH GGNGARGGNTAYYTNAARCARTTYMGNTTYGGNYTNAARAAYTGGTGGCARGTNTTYCAY GTNAGYGGNGCNGTNTTYGGNGGNTTYYTNTCNGCNACNGCNTCNAGYACNTAYGGNACN GTNYTNGGNGTNCCNGGNAAYCARGCNTTYYTNGGNGGNTTYYTNATGYTNTTYGGNGCN MGNYTNGCNGGNGGNTGYACNAGYGGNCAYGGNYTNTCNGGNATGGGNYTNYTNGCNTTY ATGTCNTTYGTNGCNGTNCCNGCNATGTTYGGNGGNGGNATHGCNACNGCNTTYTTYATG MGNGAYGTNYTNGGNGTNGARATG------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGTTYMGNTCNGAYAARGARYTNCCNTCNGGNATGYTNCCNTCN CARCCNTCNACNCARATHTCNGGNTTYAAYGGNGGNACNAAYTTYTAYGGNCARGGNAAY YTNTCNYTNCARCAYMGNGCNATHGGNGCNAAYCAYTTYMGNGGNGGNAAYAAYGCNGGN CAYATHACNCCNACNAGYATHAAYCCNGGNTTYCCNYTNGGNYTNCARCARCCNCARCAR CARCCNCARCARCARCARCARCAYTCNCCNAAYAGYYTNGCNGCNATHGGNTCNMGNAAY GTNYTNAGYGTNCARAGYCARGGNGGNCARCARAGYATHGTNAAYATGCARAARMGNTCN TTYAGYTCNGCNGGNCCNATGCCNAAYTTYGCNTCNACNTAYGGNTTYGGNGGN------ GCNGTNGAYTCNCAYCCNACNATHGAYYTNTCNGAYTTYCCNACNYTNAGYAGYMGNTCN TCNGCNACNCCNAAYCCNYTNCCNTCNACNMGNAAYTAYGTNGGNATGGTNAGYAARCCN GCNCARGAYTCNGCNCCNGARTTYAAYATHTCNCARGARGARTTYCCNGCNYTNCCNGGN TCNCARAAYCCNCCNGTNCARTCNGGN---TCNGARTAYMGNGGNMGNGGN---MGNAGY AGYMGNGGNMGNGGNGGNCCNCCNMGN---GGNAGYTTYMGN---GGNMGNGGNAGYTAY ---ATHGAYMGNGARGGNGGNMGNGGNGGNTTY---MGNGGNMGNGGNGGNTTYTCNMGN GGNMGNGGNGGNCCNCCNMGNAGYMGNGAYGAYYTNTCNCCNCCNMGNATGTCN---CAR AGYTAYCAYGAYTCNACNGAYMGNGGNMGNGGNCCNCCNMGNAGYMGNTCN---GAYMGN TAYGAYGAYAAYTTYGAY---AGYMGNCCNTCNATGMGNATGAARGAYYTNTAYTCNTCN CCNCCNMGNGGNTCNGGNMGNAGYTTYGAYMGNCAYTCNCCNCCN------CCNMGNMGN GARMGNGAYTAYGCNCCN---MGNCAYAGYGAYCAYYTNAGYTCNMGN---GAYTAYATH TCNCCNMGNAGYTAYAGYCCNCCNMGNGAYACNGGNTAYAGYTCNTCNTAYAARGAYTCN TAYAGYTCNGGNYTNMGNGARGAYMGNYTNTCNATHMGNGAYTAYCCNCCNMGN------ TCNAGYGAYTAY---------GAR---CARMGNMGNGAYTTYMGNGAYTCNCCNMGN--- GAYTAY------AGYTCNMGNGAYTAYTCNTCN---------MGNAAYGGNGARTTYMGN GAYTCNYTNAGYACNMGNGAYTTYMGNGAYGGNCCN---------MGNAGYTCNGAYMGN TAYAGYGGNAGYGGNGGNGGNMGNGGNAGYMGN--------------------------- ---------------GGNMGNTCNMGNTTY------------GAYGAYAGYMGNGGNCCN CCNCCNMGNGARTAYGGNGGNMGNGGN---------------MGNGGNAGYMGN---GAY GAYMGNGGNAGY---AGYMGNGGNTTYATGAAYGGNGGNTCNMGNGGNTCNMGNGGNCCN CCN---------MGNGGNMGNGGNMGNGAYTTYTCNGGNGAYMGNMGNTCNCCNAGYMGN GARGGNGCNGGNGGNAARMGNCCNMGNYTNGAYTCNGGNGAYTAYMGNMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATHGARGARCAR ATHAARTTYACNYTNGARGGNATHAARTCNTTYCCNGTNAARGAYMGNTCNATHTGYGTN GARATHGCNYTNAARACNAGYGAYGGNGAYCAYATGTTYYTNGARACNTGGGAYATHAGY TTYAAYYTNAGYAGYYTNGAYATGTCNGCNAGYAARATHCARCAYATHTTYACNMGNATG GGNYTNACNYTNAARTCNYTNYTNTCNGCNACNMGNGCNACNCCNGCNTAYMGNYTNGCN AARAAYCARGGNGARAARGGNGGNGGNTAYAARYTNAAYTAYMGNTTYTAYYTNGGNCCN CCNAARACNCAYATGYTNGGNGARGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CCNTCNCCNAAYGGNGCNATHCCNCCNCCNGCNCAYTCNCARCCNMGN AARMGNGCNTAYCCNTTYGAYCCNTCNCARGGNGTNTTYCCNAGYCCNGAYATHGTN--- ---------------------------------------YTNTGYGARYTNATHCCNYTN ACNACNTCNYTNYTNTCNGTNAARGARATHYTNATHGTNTTYGCNMGNAAYYTNGTNACN GTNYTNGAR------GARYTNAAYGARAGYTCNGARYTNTCNCARGAYGCNATHAARCAY YTNAARAGYTTYTGGTCNYTNTGYTCNAGYCARCARAAYTTYYTNTCNTCNACNCARYTN TTYGGNAARTGGAAYTCNGARYTNYTNGARYTNATHACNCCNYTNGCNTCNGTNTTYATH GAYYTNTCNATHTCNGCNTAYGGNCARAARGARAAYYTNTCNTTY------TGGTCNAAR AARYTNTAYAGYTGGYTNACNTTYGAYYTNTCNGARMGNGCNATHAARGTNGCNYTNYTN GARGTNACNGGNCAYACNMGNGAYGGNGCNGARATHGCNMGNACNYTNYTNMGNCARGTN YTNACNMGNAARTAYATHAGYTCNTGYGCN---GAYTAYYTNYTNCAYTTYYTNYTNGTN AARAARTGGAARCAYGTN------------TGYGAYTTYACNGARATHTCNAARTCNYTN AARGCNCCNTCNTCNTTYYTNGAYTGGYTNAARACNTAYTGGMGNGAYGCNGAYGAYTAY ATHCCNGAYGAYAARAGYYTNAARGGNTCNCARGTNAGYCARTTYYTNYTNGAYYTNGAY ACNGAYCARGTNYTNGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GGNAARGGNACNMGNAARMGNACNMGNCARTGYATHGGNCARMGNTAYCAYGGN AARCCNTGYCCNGGNGAYGARGAYGARGARGAYTCNTGYCAYMGNGARCCNTGYCCNGTN YTNCCNMGNCAYTTYCARATGTCNCARTGYAAYGAYAARAAYTTYACNTGYACNAGYAAR AARATGTGYGTNYTNTCNAAYCARAARTGYGAYGGNACNGTNCARTGYCAYGAYGGNTCN GAY------------ATGGARGGNYTNAARYTNGGNGAYTCNGARCARCARCAYTAYGCN GARYTNTTYCARGCNTAYGAYGTNGARGGNAGYGGNAARATHACNGGNGCNAARGCNTCN GARYTNTTYTGYGCNTCNGGNYTNAAYTCNGARATHYTNMGNCARATHACNGARYTNTGY GGNGCNAARMGNYTNGGNCAYTTYGGNMGNAGYCARTTYTAYATHGCNYTNAARYTNGTN GCNATHGCNCARGCNGGNYTNCCNGTNAARYTNGAYTCNYTNAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TCNTCNAARTTYAAYAGYYTNAAYACNACNAAYGARCCNGAYATHATHGTNCCNACNTTY MGNCCNCCNCCNGAYATHAAYAARYTNYTNGAYGCNCCNTCNCCNATGCCNCCNYTNCAY TCNTCNCCN------YTNCCNAARCCNCCNCCNTTYAAYAGYYTNAGYTCNACNTTYCCN GCNGGNCCNATHTTYCCNGAYTCNTCNCARCARYTNCARYTNAGYGTNCCNACNGTNACN TCNCAYGAYGGNAARTTYCARYTNACNATGCCNATHAAYGAYTTYAARCCNGARGARYTN TCNGTNAARACNCARGAYMGNAARGTNATHATHTGYGCNAARCAYGARGTNCAYACNGGN AAYMGNAAYCAYACNATGGARATGAAYMGNGARCAYAGYYTNCCNGAYAAYGTNGAYCCN YTNACNGTNAARGCNTTYTTYACNGAYACNAAYATGYTNATHGTNGARGCNCCNTTYYTN MGNYTNTGGCARACNTCNTCNACNAAYGCNGARAGYGARGGNGAYTGYGAYTCNACNCCN ACNACNCCNTCNGAYAAYACNCCNTCNGCNTGYTCNACNTGGAAYAAYTGGCCNAAYCCN CCNGGNAAYAAYAARATGGAYCCNTCNMGNCCNCAYACNATHAGYTCNGCNTAYGARAAR GGNCAYGGNMGNCCNGCNYTNAARCCNGAYATGTTYGARCCNCCNCCNGCNGGNGTNGAR ATGMGNCCNAARCCNTCNMGNTCNAAYAGYCARAGYAAYGARTTYACNGAYGAYGARATH MGNCAYGARYTNGCNCARYTNGGNTAYCAYAAYGTNCCNGAYAAYAARYTNGARGARTTY AARAARGAYYTNATHACNYTNATHTCNMGNGARMGNAGYAARTCNAAYTCNYTNAAYAGY AGYGGNACNAGYGAR---CCNGGNGARGAYAARACNTCNCAYTAYCAYCARCAYATHAAY TCNGGNTTYGARGCNGAYGARAGYTTYAAYAAYCAYGGNAGYCARTGGATHGGNCARTCN MGNTTYAAYGARGAYTGGAARTAYCARGGNCARMGNCCNCARACNGCNGGNMGNGGNMGN AAYTAYTAYGAYGTNGARCAYCAYCAR--------------------------------- ---------------------------CCNTCNTCNYTNYTNCAYCARGAR--------- ------------------------MGNAAYCARAGYTGYYTNTCNGAYGAYATHTCNGAR ACNTGYTCNGARAAYMGNTAYATGAARMGNAARACNTCNMGNAARACNCCNAAYGGNTGY MGNYTNGTNGAYGARTCNTTYACNGAYACNGAYTCNGGNGTNTTYGARATHTAYGARAAR ATHAARAAYYTNGCNATGMGNGARTGYGARTGYGGNAARACNMGNAGYAARACNGGNGAY GTNGARCCNCCNTAYMGNATGAARAAYAARGTNAAYAARTAYCCNTCNGTNATHAARAAR ATHGARCCNCCNCAYACNMGNAAYYTNGTNAARACNAAYATHAAYGAYMGNCAYCARATG TAYAARCARGCNTGGAARACNCARCCNCCNATHGGNGAYGAYCAYMGNATHCCNYTNMGN AARGCNGTNCAYGCNCARYTNYTNMGNMGNGAYGARGTNAARYTNAARCARAARGTNTAY ATHCCNAAYTTYTAYGTNCCNCCNCAYGARAARYTNMGNAARGAYGTNMGNTGGMGNGTN MGNCARGCNTGYGARAAYTAYGARYTNCCNAAYCAYGGNTAYTAYCAYGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CARCCNCAYACNATHTCNACNCAYGAYCAY TAYTAYAARGGNATGYTNYTNMGNTCNGGNAGYCAYATHAARGGNGCNTCNMGNGCNGCN ATGGTNYTNYTNATHGARATGGARTCNAARMGNMGNMGNMGNMGNGGNTGYTGYTGGTGG TTYYTNCCNYTNYTNYTNYTNYTNCCNYTNGCNATGYTNGCNGGNTAYTAYGCNMGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARTAYAARTGYCCNTCNMGNYTNGCNAGYMGNTTYTCNCARATGGTNATHYTNGAY AARCARACNAAYAARTCNGAYTAYCAYYTNCCNYTNGCNAAYTCNATHACNACNACNATH ATHGAYCCNGAYCAYCARAAYAARACNTCNGARATHAARGAYCCNYTNTCNACNCAR--- ------CAYGCNCCNATGAARGARGCNAARGARATHATGMGNATHMGNCAYAARAARATG AARAARCAYAARYTNAARAARYTNMGNAARMGNATGTAYTTYGTNTGGMGNAARCARAAR ATGACNMGNAARGCNAARMGNGAYGGNATHTAYTGGAARGARATHTCNGARATHAARAAR GARGGNGARGAYTTYGAYGCNGARACNTTYGTNAARAGYCARYTNGARAARGCNMGNMGN GGNGGNTAYTAYATHAAYGTNTTYCAYTCNAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARATHYTNACN ACNYTNAARTCNGCNYTNYTNYTNTTYATHATHACNYTNGTNTAYCAYTCNGTNGCNGTN YTNTTYGGNGCNCCNGTNTTYACNYTNGTNTCNGARACNTTYCAYTTYGCNATGYTNYTN TCNGTNYTNACNGCNYTNCCNATHTGYGCNGTNGCNGGNCCNMGNYTNGAYAARTGGATG GAYATHTTYATHATHGAR---MGNGARCCNGGNYTNGARTCNATHGTNTAYYTNACNACN ATHGGNGCNYTNYTNGGNGCNTGGYTNGGNGCNATHCCNATHCCNYTNGAYTGGGAYMGN CCNTGGCARAAYTGGCCNATHACNTGYTCNATHGGNTCNGTNTCNGGNTAYTCNATHGGN YTNTTYYTNGCNTCNYTNCAYYTNCCNCAYCARTAYAARGCNYTNATGAARCAYAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNGAYGARGARAARTAY GGNYTNCARGCNCARATHGAYCAYAARGCNACNTTYATHAARGARTAYATHCCNGCNGAY GTNAARYTNATHYTNATHGGNCAYTCNATHGGNTGYTAYTTYATHYTNAAYGTNYTNGAY AARYTNTCNYTNCAYTGYGTNCAYCAYTGYTAYYTNYTNTTYCCNACNATHGARMGNATG GCNACNTCNCCNAAYGGNGTNGARYTNACNCCNGTNTTYMGNTAYTTYMGNTAYATHATH ATHTTYYTNGCNTTYYTNTTYATHYTNTTYCCNYTNACNATHMGNAARACNATHGTNGAR TTYATHTAYMGNAARACNAGYTAYCCNCCNTGYATGACNTCNGCNATHYTNAGYACNGTN AAYCCNTGGACNGTNAAYTTYTCNACNTTYYTNGCNAARATHGARATGAAYAARGTNACN GAYYTNCARAARGAYGTNGTNAARAARCAYYTNGGNAARYTNAGYYTNTAYTAYGGNGCN TCNGAYCCNTGGTGYCCNGTNCARTAYTAYAAYGARATHATHGARGARTTYCCNACNYTN GAYGCNMGNGTNTGYGARYTNAAYATGAARCAYGCNTTYGTNATGGTNAARGCNCARGGN AAYCARATGGCNGARYTNGTNTGGCARTGGYTNCARYTNMGNCAYMGNAARCAYGGNTTY TCNTGYYTNACNYTNGAYGAYAGYMGNTCNMGNYTNTTYGCNAGYTGYACNGAYGAYAAY ATHTAYGARTAYAAYYTNAARTCNGTNGARACNAARCCNGTNCAYTGYTTYMGNGGNCAY AARAAYTCNACNTTYTAYGTNAARACNGCNATHAGYCCNTAYGTNTGGCARATHAAYAAR MGNGARGCNCCNCCNATHYTNYTNAARGCNCAYGAYGCNGARGTNACNTCNGTNGCNTGG TGYCCNATHGAYYTNACNAARMGNAGYTAYAARATHYTNTGYGAYTAYGARTGGATHCAY AAYTTYCARGTNACNGAYATHTTYAARAARGAYATHYTNAAYAARATHCCNTTYTCNTGG TAYTCNTGYYTNGTNAARYTNAGYGTNGARGARYTNAAYGAYGTNCCNTTYYTNGGNGGN AAYAGYMGNTCNAARCAYCCNGARTGGCCNTCNTCNYTNCAYGAYTTYYTNYTNGARTCN AGYCARYTNTCNGAYYTNMGNCCNCARAGYGCNAARGTNAARCCNATHGARATHAGYCCN GAYATGGCNMGNGGNATGAARAGYAARAARYTNCAYGARGTNACNMGNATGGCNTCNYTN GTNAAYCARATHTCNGARGARGCNAAYTGYAAYYTNATHATHGAYGTNGGNTCNGGNYTN GGNTAYYTNGAYCAYGTNYTNCAYCARACNTAYGGNYTNAARGTNATGGGNATGGARACN GTNCARAGYCAYGCNTCNGCNGCNGARAARMGNGCNGTNAAYCARGGNATHACNTGYAAY GGNATHAARAGYYTNCARTGYCAYATHGARGAYAAYAARGAYTCNTAYGARGCNTTYGTN ACNAARGTNGARTCNACNTTYCCNACNYTNAAYTGYGAYTGYGCNYTNMGNTAYGGNGCN MGNACNCARGCNGARGARMGNCCNMGNATHTGYYTNATHGGNYTNCAYTGYTGYGGNGAY YTNTCNCCNACNATGATHTCNTAYTTYTCNTCNTGYGARTAYATHAARGCNATHTGYTGY GTNTGYTGYTGYTAYCAYAARATGTCNTAYTCNAAYAARAAYTTYGARAARTTYCCNYTN AGYGTNYTNGGNAARAARATHTGYACNCARATGACNCARGAYCAYGGNCARTCNTTYATH ACNCCNTAYACNYTNMGNYTNGGNGCNCARGARACNMGNCAYMGNTGGCARCARCARACN AARGCNGAYCAYGARTCNCAYACNAAYCAYGTNGCNTTYMGNGGNATHYTNTGYYTNACN GAYGARGARGARGGNTAYATHMGNCARAARGTNMGNCAYTGYAAYTTYGARTCNATHCAR MGNTTYGCNGAYTCNTTYTAYACNGARGAYCCNTCNGTNGTNGAYAARMGNTCNCARYTN YTNTCNYTN---------TAYGAYYTNTGGAARAARAAYTTYGAYGCNATHGARATHATH ACNYTNYTNCARGTNATHYTNCARCCNGTNATHGARACNYTNYTNTAYCAYGAYMGNGCN CARTGGYTNACNGARCARGGNCAYCAYAAYGTNAARGTNATHCCNATHTTYGAYGARTTY ATHTCNCCNMGNAAYYTNGCNYTNGTNGCNYTNAARTCNYTNTGYCARCARTGYGTNCAR AARTGYGTNTCNAAYTCNAGYTGYACNATGAGYAARATHTTYTCNGARAARYTNAGYAGY MGNGTNMGNTTYGCNACNAARAAYGTNTGYMGNAARYTNGAYATHYTNTCNGARYTNYTN TCNAARCARTGYAAYYTNGTNATHCCNCARMGNATHMGNMGNYTNTAYCARATHYTNYTN YTNTAYMGNAAYYTNTAYGGNGARCAYYTNYTNAARGARAARGTNAGYTCNCAYTTYAAY MGNATHMGNAARAARCCNYTNATHGCNYTNYTNTCNGCNTCNTTYTTYGAYTGGGARAAR GARMGNGTNACNGAYGCNGARATHAARAGYTCNTAYAARGARGTNGAYGARGTNCARAAR YTNGTNAARAARAGY---GCNYTNTAYAARAAYCAYCCNGARYTNATG------------ ---------------------------CCNGAYAAYCCNGARTGGGARCARATHGTNGAY CARGARGAYTTYAARGTNTGGMGNCAYCARATHMGNAAYTCNYTNYTNTAYCARTAYMGN GTNYTNGGNCAYTTYAARGAYATHCCNGCNAARGCNTTYTAYAAYACNCARGTNGAYGTN CAYTAYTGGAARGAYTGGGAYACNCARACNATHGAYGTNAGYATHGTNGAYAARGAYTCN AARACNGGNTCNGARGTNATHCAYTGGYTNTAYAARTTYCCNTAYCCNATGTAYCCNMGN GARTAYGTNTAYGTNMGNMGNTGYATGTCNTAYCCNGARAAYAAYGCNATGATHATHACN GCNMGNGCNACNGARCAYCCNMGNTGYCCNYTNGGNAGYAAYAAYGTNMGNATHGARACN TAYACNTCNCARATGGTNATHACNCCNTAYACNATGTTYGAYGARAAYGGNTTYTCNTAY GTNATGTCNTAYTGYGAYGAYCCNCARACNAAYTTYCCNCCNGTNTGGTAYAAYTGGGTN GCNAGYGCNGGNGTNCAYGARTTYYTNGARMGNATGCAYMGNGCNGCNYTNATHAARCAY GCNAAYGGNATH---GARATGACNTCNAAYMGNATHGAYAAYCAYCCNCARAAYYTNTAY TCNGGNATGGTNCAYATGYTNYTNMGNYTNAARGARGTNGTNCARTGGACNMGNATGACN GCNYTNGARYTNATGYTNCAYYTNGTNTCNATHTTYATHTTYTCNTTYYTNGTNGCNACN AARGTNGARGGNGAYATHACNGTNTCNTGGCCNGTNATHTTYTCNCCNYTNTTYATHTGY GAYGGNYTNAAYGCNTAYYTNTGYGTNATHATHTTYGTNMGNCARTAYMGNGARTAYGAR YTNAARCARGCNTGYYTNMGNYTNTCNAAYTCNYTNTCNGTNATHGCNYTNATHTTYACN TTYAARYTNYTNYTNTGYCARAARYTNGARAAYGGNGGNYTNACNTGYTCNGARGTNTTY GCNCCNATHTTYGTNYTNTCNCARGTNTTYATGTTYMGNGCNTGYMGNATGCAY------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGCNGAYMGNGTN GARCCNCCNCCNTTYGARAAYGARGARGAYGARGTNAARGARGARGAYGAYYTNTTYTCN GAYGCNAARGARAARCCNTCNTCNCCNGAYACNGTNAGYCCNGAR------TCNAARAAY TCNACNGAYGARAAYCCNTTY---AAYGARGAYAARGAYGARGAYGAYATHTTYAARGGN GAYAGYTCNGARATHAARYTNGARTCNGAYGARGARGAR--------------------- ---------------------GCNACNGGNGTNGAYCAYGAYACNTCNAARACNGARGAR ACNGCNGCNGCNTCNTCNAAYAARGARATHACNCCNGARATHTCNGTNTCNGARGTNATG ACNGCNAARACNAARATHTCNGCNCCNTCNYTNAARTCNGAYGAR------YTNGGNGAY AAYGAYGARAARGARCARTAYGARYTNGAYATHAARATHACNGARAAYYTNAARATGGGN GAYGGNATGTCNGCNTAYATGGTNTTYAARATHGTNTCNAARACNACNAAYCCNGCNTTY MGNCAYCCNGARAAYACNGTNYTNMGNMGNTTYAGYGAYTTYYTNGGNYTNTAYTCNAAR YTNGCNGARAARCAYGTNCCNYTNGGNATHATHGTNCCNCCNGCNCCNGARAARAGYGTN ATHGGNATGACNAARGTNAARATGTCNAARGARGAYTCNGGNTCNATHGAYTTYATHGAR MGNMGNAARGCNGCNYTNGARMGNTAYYTNATHMGNACNGCNGCNCAYCCNGTNYTNGCN GCNGAYTCNGAYTTYATHGARTTYYTNGARAARGAYGGNGAYYTNCCNAARGCNACNAAY ACNTCNGCNYTNAGYGGNGCNGGNGTNATGMGNYTNTTYCAYAARATGGGNGARTCNATH GARAARATHACNYTNAARGTNGAYGARAGYGAYGARTGGTTYGARGARAARCAYCARCAR ATHGARGCNYTNGAYCAYCARYTNAARAARYTNCAYTCNAGYYTNGARACNYTNGCNGCN CAYMGNMGNGARYTNTCNGGNAGYACNGCNGTNTTYGCNAARAGYGCNGCNATGYTNGGN AAYGTNGARGARCAYACNGCNYTNTCNMGNGCNYTNTCNCARYTNGCNGARACNGARGAR AARATHGARATHGTNCAYAARGAYCARGCNGARGTNGAYTTYTTYACNATGTCNGARYTN ATGAARGAYTAYGTNACNYTNATGAGYGCNGTNAARGAYGTNTTYCAYGARMGNATHAAR ACNTAYAARCARTGGAARGAYGCNGARACNACNYTNGGNAARAARMGNGARAAYAARGCN AARYTNGARATGCARGGNAARACNGAYAARYTNTCNCARGCNMGNACNGARATHACNGAR TGGGARYTNMGNGTNGARAARGGNCARGARGAYTTYGARAARATHTCNAARACNATHMGN AARGARGTNYTNMGNTTYGARAARYTNMGNGTNTCNGAYTTYAARACNAAYGTNATHAAR TAYYTNGARGTNYTNATGGAYAAYCARGARAARYTNATHAARTAYTGGGARACNTTYYTN CCNGARGCNAARGCNATHGCNGAYGAYGTNCAYGARYTNMGNGGNCCNMGNCAYMGNGCN YTNAARCAYGTNMGNCAYCCNTAYTAYGAYGAYAAYACNAGYTAYAAYAGYAGYGAYGAY ATHYTNAAYACNYTNMGNTTYAGYMGNCARGGNCCNYTNAGYAARGCNGCNMGNMGNGCN MGNYTNACNTCNTTYAAYGCNMGNYTNCAYAARCARMGNMGNGTNAARGCNTCNYTNMGN YTNAAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CCNAARACNCCNATGGAYGAYGARGAY ACNGCNGCNGCNAGYAGYCAYGTNAAYGGNGAYGGNGAYMGNCARGTNYTNGCNCCNACN GARGGNCCNMGNGARGAYYTNATHAAYACNGCNATHAARTTYYTNCARAAYCCNAARGTN ATGGGNAGYCCNYTNYTNCARAARAARGCNTTYYTNAGYAARAARGGNYTNACNCARACN GARATHAAYATHGCNGTNGARMGNGCNGGNGTNAARGARGTNGCNAAYAAYGAYGGNGGN AAYAGYCARGCNMGNCCNCCNCCNCCNGGNTAYCARCCNGGNATGATG---GTNCCNGCN TCNGAYCCNTAYGGNCCNGTNCARCCNCCNATHCCNGCNCARTCNMGNYTNGCNCARATH MGNGAYYTNACNYTNACNACNGTNGTNATHGCNAGYTTYTCNTAYGCNGCNTAYCAYYTN TAYAARGCNTAYATHGARCCNYTNATHMGNGGNAARTCNYTNCARGARAARMGNATHGAY MGNYTNGARTCNCARGTNGARGARATHCAYAARTCNGTNAAYGARTCNYTNTCNGARATH AGYAARACNYTNGCNGCNATHCARATHAGYGTNAAYAAYCARAAYCARCAR---CCNGTN GCNAGYCARGTNGGNMGNGGNATHACNGAYYTNAARGCNGAYATHTCNTCNYTNMGNAGY YTNYTNYTNAAYCAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNGCNACNACNCARYTNCAYGTNGAYGCN TTYCAYTCNCAYTTYTGGATGGCNYTNTTYCARGGNGARAARMGNTGGACNTTYTTYGAY GARAARGAYATHGCNTTYYTNTAYCCNCARTGGTTYCARTCNATGGAYCCNGTNTTYGAY GTNGAYYTNACNCARCCNGAYYTNAARMGNTTYCCNYTNYTNGCNYTNACNMGNCCNCAR CARTGYGTNYTNCARAARGGNGARYTNYTNTTYGTNCCNGCNGGNAGYCCNCAYTTYGTN GARAAYYTNACNCCNAGYYTNGCNATHTCNTCNAAYTAYGTNGAYCAYTCNAAYATHCAR AARGTNTGYGARGARYTNAARGTNAAYGCNYTNCARGAYCCNMGNGCNGGNGAYYTNYTN TCNCARYTN--------------------------------------------------- ------------------------------------------------------------ ---------------------------------------ACNGTNAARMGNTTYACNGTN ACNGAYGCNGTNTCNACNAAYATHAAYGAYCARGCNMGNAGYGGNTGYYTNCARACNGCN TCNACNGARGCNAAYCARCARCARAARATHGARCAYATHMGNGCNAAYMGNCARATHAAR CAYTCNGAYATHTCNCARMGNYTNGGNATHTCNAARNNNAGYTGGATHTAYATHATHMGN CARATHYTNGGNTAYMGNAARGTNTGYGCNTGYTGGGTNCCNMGNATGTTYACNCAYGAR NNNCAYYTNAAYMGNTAYGARCARGARGGNGAYGGNTTYYTNMGNAARATHGTNACNGGN GAYGARTCNTGG------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TAYTAYGGNTCNMGNAARCCNAARTCNCARATH MGNTCNAGYYTNCAYAAYGTNAGYGAYYTNTTYGTNATGGGNGGNGCNYTNGTNYTNGAR TCNYTNGCNYTNYTNCAYTGGTGYGARMGNCARGGNTGGGGNCCNTTYGGNYTNTCNGGN GTNTCNATGGGNGGNCAYATGGCNTCNYTNGCNGCNACNAAYTGGGARAARCCNATHTCN YTNGTNCCNYTNYTNTCNTGGAGYACNGCNTCNTGYGTNTTYACNCARGGNGTNATGAGY GGNGCNATHCCNTGGCARGTNYTNCARGARCARTTYTTYAARAAYAAYYTNTAYCAYGAY GARATHAGYAARYTNATHATHTCNCCNGARAARGCNTAYGAYATGGGNCARCARTTYGTN ATHAAYTAYTAYGCNCAYACNAARCARTGGCARCARACNTCNGAYAGYAARAARGARAAR AAYTCNYTNACNYTNAAYCAYGCNGARGCNAARTCNAARATHAARATH------------ ------TTYCCNAAYAARAAYGARAARYTNMGNAAYYTNCARGARGARTCNTAYGARTTY ATGMGNGGNGTNATGGAYGARTGYACNCAYYTNGCNAAYTTYTCNGTNCCNGTNGAYCCN GARYTNGTNATHATHGTNTCNGCNACNCARGAYGCNTAYATHCCNMGNGAYGGNGTNYTN CCNYTNGAYAARYTNTGGCCNGGNTGYGARGTNMGNTAYGTNGAYCARGGNCAYATHGGN GCNGTNYTNYTNCAYCARAAYGTNTTYMGNMGNGCNGTNACNGAYGCNTTYGARAARCAR GTNMGNAARTAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGAAYMGNGGNGTNAGYACNAARYTNGTNCAYGCNTCNTCNATGCARAGY GTNMGNGAYAGYGTNTTYTGYAARTAYAGYCAYMGNGAYTGYACNCARAAYTGYATHGAR GGNTAYGAYTTYTGYATHMGNCAYATHYTNGARGAYAARACNGCNCCNTAYMGNCARTGY GCNTAYATHACNAARGGNGGNMGNAARTGYCCNGCNGCNGCNCCNAARYTNGARAARAAR GARGGNTAYTGYAGYTTYCAYACNAARAARGGNYTNATHTCNMGNCARMGNYTNGCNMGN AARMGNMGNYTNAARGARACNCCNGAYAGYYTNYTNGARGAYYTNGTNGTNACNACNTCN GCNATGGARTCNAAYCAYTTYGTNGARCAYMGNMGNGGNAARATGTAYAGYGAYAGYATH GCNTCNMGNGCNYTNGAYTAYGCNAGYTCNAGYGAYTCNGARGCNGARCCNYTNYTNGTN GARCAYGCNTGGMGNGAYTCNGGNGAYAGYGAYGCNGARAGYATHGAYAGYGAYCARGAR GAYATHYTNAARTAYGCNGGNGTNTAYACNACNGARGARGTNGCNCARGTNYTNMGNGAY AARYTNATHMGNYTNCARGCNYTNTAYATHGAYCARTTYAARMGNYTNAARCAYATHYTN TTYACNAARMGNMGNAARTAYYTNCARGCNCARAARACNGARAAYGAYYTNTAYGGNAGY ATHAARMGNTAYAARGARGAYCCNCAYCARAARGARAARTAYGARAARYTNTGYGCNATG AARMGNTAYCAYMGNAARTTYGGNGTNGARGCNYTNATGCARTGYCARTCNACNMGNMGN MGNATHAARATHACNGAYGGNTCNAGYCAYAARYTNCCNAAYCCNGTNCARTGYGGNTTY GTNGAYGARGGNATGMGNTGYAGYCARACNGTNGTNCCNYTNAGYAARTAYTGYCARAAR CAYATHYTNCAYGAYCARAAYCARGTNYTNTAYMGNCCNTGYCCNTTYGCNGAYAGYCAR TGYGGNMGNCCNGTNCCNTCNYTNYTNGGNAGYCCNTTYTGYTCNYTNCAYCAR------ ------------------------------------------------------------ ---------AARTGYAGYGARYTNGGNAGYATHCARMGNGARATGGARAARYTNAARGAR GCNYTNTCNTCNTCNGAYTAYMGNATHAARTGGTTYCARAAYAARYTNAARGAYGARYTN GARTCNCAYAARGARACNAARTCNAAYYTNGAYAARACNTCNTCNAARYTNAARGARACN AARGARGARACNGARATHATHMGNMGNGARTGYCARGCNATHGTNAARACNTAYCARGAR TCNGARGARATHAARTCNAAYAGYYTNGAYAARGARYTNAARATGAARGARTCNCARYTN MGNCAYCARATGCARGARTGGAAYGAYAAYGARGARATHCAYCARMGNACNAARAARGAR YTNGARACNYTNAARGGNCARCAYAARGARGCNGTNTTYCARYTNAGYTCNYTNAARGAR AARGTNCARAGYYTNGARGTNTCNGTNGCNGARAARGGNTCNACNATHACNCARTCNAAY GARYTNYTNAAYAARCARAARGCNGAYATHACNAAYTTYACNTCNAARYTNMGNGARAAR CARAAYYTNGAYGAYGAYTTYAAYMGNGCNCARGARATGATHAARGCNYTNGAYAARGAY GTNTCNGARYTNAARATHGGNAAYMGNGAYYTNCARAARGAYATGGAYTCNTGYMGNGAR MGNGARTCNAARATGYTNGCNYTNCARTCNGARYTNAGYMGNACNAAYGCNTGYYTNMGN TCNGARAAYACNACNYTNAGYAAYAARGTNACNAAYCARACNGCNGAYATHGARMGNYTN AARATGGARATHCARGARYTNGARACNACNGTNAARCAYYTNACNGAYTCNGTNGARGAY GARAARAARAAYAAYGTNAARGTNYTNGCNAARYTNAARGGNTCNYTNGARGARAARACN AARGARAGYTGYGAYTTYAARCARAARTGGGARGAYGARATHGAYTCNAAYAARACNYTN AARMGNMGNCAYGCNAAYAAYGTNAARGAYYTNACNMGNCARYTNCARCARGCNAARMGN MGNYTNGARGTNYTNGARGGNAGYMGNAARGAYAGYAGYGGNAGYATGGGNTCNMGNACN AAYTCNAAYGGNAGYYTNAAYTCNATGGTNGAYAAYAAYCARGGNTCNCARAAYGCNCAR TCNGGNACNAGYTCNCCNGARTTYCCNGTNATHACNGARCARGTNGARATHGAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARGCNAAR ACNGAYGGNGAYGARAGYTAYCARACNTTYGTNYTNCAYGAYGARGAYCAYACNYTNGGN AAYGCNYTNAARTAYACNYTNAAYAARAAYCCNGAYGTNACNTTYGTNGGNTAYAGYATH ACNCAYCCNTCNGARAGYAARATHAAYYTNMGNATHCARACNACNGGNAARCCNGCNYTN CARGTNYTNAARCARGGNTTYAARGAYYTNAARCARYTNTGYGGNCAYATHYTNACNACN TTYGARTCNTCNACNAARTAYTAYAARGARAAYCAYYTNGAY---TCNTCNGAYATGGAY CARTCNTGYTTYAAYTCNTCNTGYCARAARTCNTTYACNYTNTTYGAYMGNCAYCAYCAY TGYTGGAARTGYGGNGARATHTTYTGYAAYAAYTGYACNCARTTYAARMGNMGNYTNAAY AAYYTNGCNCAYTTYGAYCCNGAYGGNCCNYTNTAYAARGTNTGYAARGCNTGYTTYGAR AARGARGGNYTNACNGAYGCNCAYATHACNACNCAYACNTCNGAYTTYATHTGYYTNMGN TCNTTYTGYCARMGNYTNATHGAYGGNTTYGCNGCNAGYGTNGGNACNTCNGARATHATG AARACNTTYCARGARGTNMGNAAYGTNGTNTCNATGCCNGAYTGGATGAARTCNAGYGTN TGGATHYTNGARAAYAAYGTNACNAARTGYMGNGTNTGYATGGARAGYTTYTCNYTNATG AARAARAARAAYTTYTGYTGYGTNTGYGGNATHGTNGTNTGYAARGCNTGYTCNAAYAAR GARYTNYTNYTNTAYGTNCCNGAYGGNTCNAARATHGTNAARATGGCNATHATHAARATH ATHGGNTGYCCNGARGTNGARCCNGARGTNAGYYTNCAYYTNMGNGTNTGYCCNYTNTGY AARGARAARYTNATHTCNCARCARGTNGARGARGTNGTNGARGCNGARAARGGNGTNAAR YTNCARYTNCCNAAYTAYACNAAYGTNGTNGARGCNYTNGARGAYGGNTCNMGNAARACN CCNAARCARAGYAAYATGAARGTNYTNGCNAARGCNCARGARGAYGTNGCNGAYGCNYTN GCNAGYCAYATHACNYTNGTNCARCARYTNAARAARYTNTCNCCNCAYACNYTNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNGCNATGTGGGAYYTNGARCAYTGYGAYCCNAARAAR TGYACNGGNAARAARYTNAGYMGNYTNGGNTTYGTNMGNACNYTNMGNYTNAAYCARMGN TTYGGNGGNYTNATHYTNTCNCCNGTNGGNACNAARTGYGTNGCNCCNGAYGAYMGNGCN ATHGTNGARACNAAYGGNATGGCNGTNATHGAYTGYAGYTGGGCNAARYTNCARGAYACN CCNTTYGCNMGNATGAARGGNGAYCARYTNMGNYTNYTNCCNTAYYTNATHGCNGCNAAY CCNGTNAAYTAYGGNMGNCCNTGYAARYTNTCNTGYGTNGARGCNTTYGCNGCNACNYTN ATHATHACNGGNTTYGCNAARGARGCNGARYTNYTNYTNAGYAARTTYAARTGGGGNMGN TCNTTYTTYACNYTNAAYGARGARYTNYTNGAYACNTAYAGYAARTGYCAYACNAGYCAR GAYGTNGTNAARCARCARGAYAARGTNYTNGCNCARTTYGARGARGARMGNAARCARGAY AARYTNAARGAYTGGTTYTCNGTNGAYCCNGAYACNGAYGTNTGYAAYCCNAAYMGNCCN ------YTNTAYCCNCCNTCNGAYTCNAGYTCNGARGARGARAGYGAYGARGARGARGAR GARGARGARGARAARGARGARGARACNGAYGARGAYGTNGARGGNGARCARATGCARYTN CARAARGAYGGNATGGARTGYGTNTCN------AARCAYCCNATHTTYATGATGCARATH GCNGARCAYATGGARCAYCCNGARGARATGGCNAARYTNAGYTTYYTNTGYAARTAYCAR AARGARYTNGTNGAYATHATHTCNTGYATGYTNAAYAARATHAARGGNTGYATHCCNGAR GARGTNAARCCNTAYATG---GAYYTNYTNACNAAYACNAARMGNATHGCNGAYGCNGTN AARTTYTCNTGYGAYCAYAARGAYGTNYTNCARAGYCARTGYATGAGY---GARAAYATG ATGAGYTTYTCNCARTGYTAYATGGCNMGNYTNGGNAAYGTNAARAAY---------ACN ATGACNGARAAYTCNGAYCCNAARGARYTNATHTGYAGYGTNATHMGNTCNGARGARAAR TGYTTYATHGARAAYAARGGNCAYTGYAGYAAYGARTTYATHTCNYTNACNATHCARATG YTNGARAARTTYTTYCCNATGTCNGCNTGYCCN---AARYTNAGYAGYAARGAYTTYGCN AAYACNGCNYTNGGNMGNATHYTNATHAAYTCNGARGAY---YTNAARTTYAARCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CARACNCAYGCNGCNTGYGARGTNGCNAAYYTNGARAAYGTNAARCCNTCNATG ATGGGNGARMGNGARMGNACNATHCARACNYTNCARGARGARYTNAAYGARYTNMGNACN CARGTNYTNGCNATGGAYGARMGNCAYGARMGNGARAARGGNCARTGGYTNGAYGARAAR AAYAARGTNATHMGNTAYCARAARCARYTNCARYTNAAYTAYGTNCARATGCARMGNAAR AAYTCNACNYTNGARACNGARGTNCARCARYTNACNYTNGARYTNGARAAYMGNGAYATG AARYTNATHGCNYTNAGYGGNGARGARAGYGTNTGY------TTYTTYCCNGTNTTYCCN ATHGCNGCNATHYTNAAYYTNGGNTCNYTNGTNTAYATGGCNCARTGGCARCCNACNGGN GARTCNYTNYTNCCNTTYTTYATHATHATGGGNATHTGGGGNATHACNGAYGGNTTYTGG ACNGCNCARGCNAAYAGYYTNATGGGNGTNATHTTYCCNGAYAARTTYGARGAYGCNTAY GCNGGNYTNMGNATGACNCARGGNYTNAGYGTNGCNATHGCNTTYGGNTAYTCNAGYGTN YTNTGYATGATGGCNAARATHTAYATHAGYTTYGGNATHTGYTTYYTNGGNYTNGTNGGN TAYYTNACNATGGARGGNYTNYTNMGNTGGCARCARAAYAARCCNACNGTNYTNATGAAR CARACNTCNGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARACNAAYGGNTGGCAYMGNMGNYTNGARTTYCCN GGNAARGARATHATHGTNATGCAYAAYGCNAGYGTNATHYTNCARTTYCCNTCNTCNTCN ACNYTNGAYGARTGGGGNAAYGTNYTNGGNGAYCARATGMGNCCNMGNGTNGTNAARMGN GGNGTNGAYGAYTTYGCNACNATHGARTAYGGNGARMGNGARGARGTNGAYCAYYTNGTN TTYTTYGTNCCNGGNATHGARGARATGACNGARGGNAARMGNAARTCNYTNGARGARTAY GTNGAYGAYTTYMGNAGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNAARACNAARMGNGCNGGNTAYGCNCARATHAARTCNGAR TTYYTNYTNYTNAAYTAYAARCCNACNATHCARACNGARTAYYTNAGYGARGAYGTNAAR MGNAARATH------------------------GCNGAYGTNGAYGGNGARTCNCARAAY CARGARGAYAARGCNTCNGAR---------CCNCCNAAYAARAARCARAARYTNAARGGN MGNAAYAARCAYMGNCCNMGNAAYGARMGNGTNGARCARAARGAYAARYTNTGYCCNTCN GTNAARGAYGGNMGNGAYTGYAARTAYGGNGAYAAYTGYAARTTYAAYCAYGAYATHAAR GAYTTYYTNGARAARAARMGNCCNGAYATHGARAAYAARTGYCCNGTNTTYGARACNYTN GGNCAYTGYAARTAYGGNGTNACNTGYMGNTTYGCNAGYAGYCAYYTNGGNGARAAYCAY GARAAYYTNGTNAAYGARGAYYTNTAYGARACNATGAARAARAAYCCNTCNTTYYTNAAY ACNYTNAGYGAYGAYGCNMGNCAYAARYTNTGGAARMGNAARTAYGAYTTYTCNAARTCN ATGAARTCNGTNMGNGAYGTNCARAARGCNTTYGARAAY--------------------- ------------------------------------------------------------ ------AARAAYACNACNTCNGTNTGYGAYAAY------------AAYYTNACNGAYAAR GARGAYTCNACNGTNGTNGARCARAAYATH---TCNCCNTCNGTNTCNAARTCNGGNGAR AGYGARATHAAYCCNCCNGTNCCNGAYCCNATHMGNGAYGCNGAYYTNGGNAAYGGNGAR AAYYTNATHAAYAARTGYGAYGAYGTNGARATH---MGNYTNACNCCNMGNGARGTNAAR AARATHGAYTTYCAYAAYAARYTNTAYYTNGCNCCNYTNACNACNGTNGGNAAYYTNCCN TTYMGNMGNGTNTGYAARAAYTAYGGNGCNGARATHACNTGYAGYGARATGGCNYTNGCN TCNCARYTNYTNAARGGNAARGCNTCNGARTGGTCNYTNATHAARMGNCAYCCNAGYGAR GAYATHTTYGGNGTNCARGTNTGYGGNGCNTAYCCNGAYATGATGACNAARTGYGCNCAR YTNYTNACNGARACNAGYGARATHGAYTTYATHGAYATHAAYTGYGGNTGYCCNATHGAY YTNGTNTTYAARAARGGNAGYGGNAGYGCNYTNATGGGNAARGCNACNAARYTNGARCAR ATHTGYMGNAGYATGMGNGGNGTNATGGGNGARACNCCNYTNACNGTNAARYTNMGNACN GGNGTNTTYGAYCAYAARAAYGTNGCNCAYAAYATHATHCCNMGNYTNMGNGAYGCNGGN GTNTCNYTNGTNACNATHCAYGGNMGNTCNMGNGARCARMGNTAYACNAARYTNGCNGAY TGGAAYTAYATHGAYCARTGYGCNAAYYTNGGNCARCCNATGCCNGTNTTYGGNAAYGGN GAYATHYTNTCNTAYGARGAYGCNAAYYTNCAYATGGARMGNAARGGNGTNTCNGGNGTN ATGYTNGCNMGNGGNGCNYTNATHAARCCNTGGATHTTYACNGARATHAARGARCARMGN CAYTGGGAYATHTCNTCNTCNGARMGNTTYGAYATHYTNMGNTCNTTYACNAAYTAYGGN YTNGARCAYTGGGGNTCNGAYCAYCARGGNGTNGARAAYACNMGNMGNTTYYTNYTNGAR TGGYTNTCNTTYYTNCAYMGNTAYATHCCNGTNGGNGTNYTNGARCARGTNCCNCARAAY ATHAAYGARMGNCCNCCNTAYTAYATHGGNMGNAAYGAYYTNGARACNYTNATGGCNAGY ACNAAYTGYGCNGAYTGGATHAARATHAGYGARATGYTNYTNGGNCCNGTNCCNTCNACN TTYCARTTYYTNCCNAARCAYAARGCNAAYGCNTAYCAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ACNAGYTCNGCNACNGTNYTNGARYTN CARTGYAARATHAARGARYTNGARTCNYTNYTNTCNAARAARGGNGARCARYTNCARCAR CARGCNACNTCNYTNCAYGARCAYCAYMGNCARAARGTNTCNGCNYTNAARGARMGNCAY GCNACNCARGTNAARTCNYTNCARGARMGNYTNTCNGTNYTNGARCARCARYTNTCNAAY TCNCARCAYAGYGGNACNYTNCCNGARTCNGAYMGNCCNAAYGTNAGYAAYAARYTNGGN GARYTNGARMGNAARYTNGCNAGYGCNYTNCAYGAYAARGARAARGCNCARAAYGCNCAR ACNCAYYTNGARGGNGTNYTNGARGARYTNCARCARGARGTNCARMGNYTNCARGAYYTN AAYGARAARCARGARCAYGCNTCNCARAAYAARGARYTNMGNACNCARGTNYTNGARYTN TCNCARMGNYTNGARGARACNGARGARGARAARAARCARYTNMGNTCNACNYTNGARGCN AARAAYGARACNYTNTCNTCNYTNATGGGNACNAARGARGARMGNGAYGGNGTNATHGTN AARYTNGARGARYTNATHTCNAGYATHGGNGAYGARGAYTTYCARAARAARACNGCNGAR YTNYTNAAYYTNATHGAYAARGARAAYYTNGTNYTNAARGARCARAARACNAARYTNGAR GARCARGTNATHYTNYTNGARAARACNTCNTCNAAYCARATGAARGARAARCAYTCNYTN YTNGARACNATGGCNACNYTNAARTCNCCNGTNATHCARGAYGAYATHACNTCNGARACN GAYGAYACNATHGAYTTYTCNTCNAGYAAYGARGCNATGCARATHAARGARGARGARGTN GARGCNGARGTNATGMGNYTNMGNTCNACNYTNGARAARATGAARGARGARTCNACNGTN TTYGARTCNGARMGNTCNGAYTGGYTNATGGARAARGARACNYTNGARGAYATHYTNACN GAYATGCARAARAARTCNAARGARCARGARGAYGARATHGARTCNYTNAARTCNTCNGAR GGNGCNACNCARAARTCNAAYGARAGYAARCARGAYGARTCNGARATHAARATHYTNAAR YTNGARAAYCARGTNTCNTCNYTNCARGARGARAAYCARGAYYTNGARMGNGCNYTNGAR GARYTNGAYACNCARCAYTCNGARGCNYTNACNCARYTNATHTGYCARMGNGAYAARATG GCNACNGARATHGCNGARTGYMGNACNGARATHAARTCNYTNAAYYTNACNATHGAYCAR ATGAARGAR------------------GCNAGYGAYAAYGAYAAYYTNCARAAYYTNGAR AARTAYCARAARTAYGARCARGARGTNGCNGARTGGAAR---CARAARAGYYTNGAYGAY ATGGARAAYAARATHTCNGARYTNAARGARAARYTNGARAARGGNGGNYTNGTNATHAAY GAYYTNCAYATGGAYAARCARGAYYTNGARCARCARYTNGTNAARGCNMGNGARGARATH GARGTNAARGTNTCNAARYTNAARGARAGYMGNACNCARMGNGCNGARATHGARAARGAR MGNAARGARATGGARTGGAARYTNMGNGARATGGARGARMGNGTNGARGARACNGARCAR GARYTNGARAARTGGCARCARATGAAYGARGARMGNCARACNCARACNATGGARAAYCAR GAYCAYGARATHGARTGYTCNMGNYTNMGNTCNAARATHCARGARATGGARCAYGARAAY GARGCNGTNAARCARAAYTTYCARGTNYTNATHGARGGNAGYAARAAYGARAAYGAYCAY CCNTCNACNYTNAARGAYTCN---------GAYATHYTNGTNGARGARYTNMGNGTNMGN CARAARYTNGARGARGAYGARAAYATHATHCARGARYTNAARGARTAYATHGARAARYTN MGNAGYGARMGNGARGARYTNAARAARGARATH------------TCNATHYTNAARTCN GARGARAAYGARCCNGGN---------------------ACNYTNYTNGARTCNGTNGAR CARGARAARTCNAARTAYGTNGARCAYATHGCNGARATGACNGCNAAYYTNGARGARMGN GARTAYGARYTNYTNAARYTNAARAGYGARYTNGARAAYYTNAAYGARGARAARTGYGAR ATHGTNAARCARYTNGTNGARAARACNGCNAAYYTNCARGCNCARGAYTCNGARYTNTTY GAYGTNAARATHAARYTNGARAAYYTNAAYGARGARAAYYTNAARYTNCARAARGAYYTN AGYAARATHCARCARTAYGAYGCNTAYATHGARGARYTNAARGCNGARCARGARGARATG GARAARYTNAARGGNGARYTNAARGARAARMGNYTNGARATHGARAAYYTNATHAARGAY AARGARGARTAYCARAARGARGTNAARATGATHAARGARGARGTNTGYMGNYTNGARGGN YTNTGYAAYGARAARGAYMGNGARATGGARTCNGTNAARGARMGNATGGGNGGNTTYGAY MGNGAYYTNTCNGARATGGARGARTCNGTNAAYATHACNAARCARCARAAYGARATGGAR AARAARAARAARGARGTNGARYTNATGGARYTNAARACNAGYAARGARGARYTNGARGTN MGNYTNAGYYTNGTNCARGARYTNGARTCNYTNACNGCNGGNCARCARGARCAYTCNGAR YTNCARTCNCARTAYGARYTNGARGCNYTNAARAGYGARMGNGARACNGCNGGNAARACN ATHTAYCARYTNGARACNGAYYTNTCNYTNTCNGARGARAARATHAAYAGYYTNAARGAR GARYTNTCNTAYGCNATHGARACNATHGAYYTNCAYAAYYTNAAYGTNGTNAAYATHAAY AARAAYTCN---------CARACNGARGAYGAYTCNTGYCARGARAAYACNGCNACNYTN GARTCNGAYYTN------------------------------------------------ ------------------------------------------------------------ ---------GAYMGNAAYGGN---------------------------------GGNATH GARTTYATGGARMGN------------GCNGTNTCNAARCCNYTNYTNTCNTCNCAYTCN CARMGN------TAYAGYCARGAYACNGAY---GAYATHGAYGAYGAY---GARGAYCAR GAYMGNTTYYTNGARYTNGARAARGARATGGARGAYYTNMGNGGNAARYTNACNGARAAR GAYGGNATHGTNGCNAAYYTNCARMGNTCNAAYTCNTCNYTNYTNGARYTNYTNGARAAR AARGCNGAYGGNGAYGGNAGYYTNGGNAAYMGNYTNAAYAGYCAYAARYTNGARTCNGAR YTNAARAAYYTNMGNGCNGARMGNGARCARATGGTNGCNGTNGTNAGYGARAARTCNMGN GARAAYTCNTCNYTNAARTCNGARATHCAYMGNYTNATGGAYYTNGTNTCNGCNGGNCAR GCNGCNYTNTCNAARGTNCARCARGAYAAYTTYAAYYTNGAYCARMGNCARCAYTCNCCN CCNAARAAYAAYGARGARGAR------CAYATGAARMGNGARGCNYTNAAYAAYATGGCN MGNYTNGTNMGNGAYAARGAYACNGARATHGARGCNYTNACNCARAARAAYAAYACNYTN YTNGCNGTNYTNCARGAR---TCNAAYGARTCNCARGCNGCNGCNCAYYTNGGNCCNYTN YTNAARGARAARGARACNYTNAGYCARCARATHAAYGTNATGGTNTCNGARMGNGARCAR YTNATHACNTGYGTNAAYCARAARCAYTCNGARTCNYTNGCNTTYCAYGCNGARGTNCAR MGNYTNACNGCNYTNYTNGCNGARACNAARGARTCNGCNGAYAARGTNAARGCNGARTAY GCNGCNYTNATHCCNTCNTTYGARGGNAARACNCARGCNYTNYTNAGYTCNCARCARGAR YTNGTNGARTGYAARCARAARYTNACNGARYTNGARATHMGNCAYGGNGARYTNATHCAR MGNTCNAAYAGYCARCARCARAGYCCNGAYTCNCCN------------ACNACN---GAY GAYYTNAARGCNGARTTYGARAARTAYAARMGNYTNGARTGYGAYTAYAARTCNATGGTN YTNGARMGNGAYGGNCARATHCARAGYYTNTCNCARAARGCNAARACNTTYGARGARACN GCNTCNTCNAARGARACNGARTGYGTNCAYYTNMGNAARCARYTNGARAAYTCNAARTTY CARYTNACNGGNYTNATHGCNGARATHGCNGAYGCNAARTCNGARAARGARYTNATGCAR CAYAARAGYGAYAGYCARGGNGARGARYTNATHACNATGMGNAAYAGYYTNAAYCARATG ACNYTNGCNYTNAARGAYAARGAYGTNGARATHYTNTCNYTNAARGAYCARATHTCNACN YTNAAYTGYGTNYTNCARAAYCARAARGGNGAYGARGAYCARGTNTCNCARYTNATHMGN GAYCAYGARTCNGCNGTNGCNGTNAGYMGNCARYTNCARCARGARMGNGAYAARAAYGCN ATGYTNGCNGARCARMGNTTYCARGARAAYGARGCNYTNAARGCNGARYTNYTNTCNCAR AARGAYAARGTNTTYAARYTNGGNMGNGARYTNGARMGNYTNMGNAGYCAYYTNYTNGAR ATHGARGARGGNTAYACNAARGARGCNYTNGAYGCNGARGARMGNGARAARGARYTNMGN AAYAARYTNGCNGTNGCNGARGARCARYTNYTNACNTCNTCNTCNCAYGTNCARYTNGCN AGYCARGARTCNCAYMGNCARATHGARAGYYTNCARGARCARYTNCAYCAYATHGCNTCN CARMGNGAYGCNGCNTAYATGCARATHGCNACNACNCARGAYCARTGYCARCARTAYGCN GCNTCNYTNAGYAAYYTNCARYTNGTNYTNGARCAYTTYCARAARGARAARGAYTCNGCN ATHGCNYTNGARACNGARAARTAYCAYGAYCARGCNAAYGCNYTNGGNTCNAARGTNAAR GAYYTNGARAARGARYTNGARGCNACNMGNACNGAYYTNACNGARGCNYTNGAYGGNYTN GARGCNGCNTCNMGNYTNAGYGARCARYTNGAYMGNAARGARAAYGCNYTNGCNGCNYTN AARGARGARGTNCARYTNMGNGARCARGCNYTNAARATGGCNGARGAYGARATHACNMGN YTNAAYTCNAGYACNGARGCNAARGTNGAYAARATGYTNATGCAYAAYATGGTNYTNACN TGGYTNACNTCNCCNGARAARAARMGNCAYGARATHGTNCARYTNATHGGNCAYGTNYTN GAYTTYAGYCCNCAYGAYTTYTCNAARATHGARTCNGCNCAYAAYCARGAYAGYYTNTGG ATHGGNTTYTTYAARMGNTCNGARAARCCNTCNCARCCNAGY---AARGTN------GAY CARTCNTTYTCNCARYTNTTYGTNAARTTYYTNGARAARGARTCNTCNCCNGCNCCNACN CCNGTNAARYTNCCNGTNGARGCNATGGCNGCNGARGCNCARYTNMGNCAYAARACNACN TTYAAYCCNTTYACNGCNCCNMGNCAYGTNACNCAY------GGNAAYGARGCNTCNGGN TCNTCNTCNTCNTCNCAYYTNYTNATHCCNCARGAYAAYCCNCAYCCNTCNCCNYTNTTY GCNCCNGTNACN------AAYAGYACNGGNGARAGYGCNATHYTNAARGAYGTNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNATHGTNCARTAYCAYCCNAAYGGNTCNYTNTAY GAYTAYYTNCARGGNAGYGAYATHGAYATGGARGARATGYTNATHYTNGGNAGYTCNGCN GCNGCNGGNATHAGYCAYYTNCAYTAYGARATHAARCARGGNACNGGNACNCAYGARAAR CCNTCNATHGCNCAYMGNGAYGTNAARTCNAARAAYATHYTNGTNAARGCNAGYGGNGAR TGYTGYATHGGNGAYYTNGGNCAYGCNATHAARAAYACNAARGARTGGGAYMGNGGNMGN GARMGNYTNTGGGTNGGNACNAARMGNTAYATGGCNCCNGARYTNYTNGCNAARTCNYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGYTNTTYAAYATHGAYGAYTGGMGNCARGGNATGGAYYTNYTNTGYGARGAYYTNAAY MGNAARYTNGTNTTYMGNGAYCAYTTYGARTGYYTNACNCARTTYGCNCCNMGNATHTCN AGYTGYATHYTNATHMGNACNCARATGTTYAARAARGCNATHYTNAAYGCNGGNATGGCN ACNCAYAARACNYTNCAYGAYATHACNTGYAAYTTYGCNGARAAYATHGTNAAYTGYYTN GARMGNCCNYTNGGNMGNGCNTGYCCNATHGCNGTNGTNGAYACNATGGTNGCNGCNYTN CAYMGNTTYYTNCCNCCNGCNTGYGCNCCNYTNCCNGCN---AARGAYGTNAGYGAY--- ---------------------------GTNACNGTNYTNGARAARGTNATHYTNGARGGN GGNGGNGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNMGNMGN GTNGCNTGGMGNCAYYTNYTNAAYGTNTTYCCNATHAAYATGTCNGGNMGNGAYMGNTTY GAYTAYATGAARMGNAARGARGARGARTAYMGNAARYTNMGNGARGARTGGGGNGARMGN TTYMGNACNAAYACNATGYTNCARGAYMGNATGGAYMGNYTNCARGAYGCNYTNAAYGCN TAYGGNCCNAAYTCNCARCAYTTYYTNAARGAYTCNGTNTCNAGYCCNTGGGARMGNGCN GTNGCNATHAAYAARGTNCCNTAYTAYATHAAYCAYGAYACNGARACNACNCARTGGGAY CAYCCNCARYTNACNACNYTNATGGAYGAYYTNATHGARYTNAAYAARATHMGNTTYGCN GCNTAYMGNACNGGNATGAARYTNMGNATGYTNCARAARAARYTNTGYYTNGAYACNGTN TCNYTNCARATGGCNACNGARTCNTTYGAYAGYCAYGGNYTNMGNGGNMGNAAYGAYAAR YTNATGGAYGTNGGNGARATHATHGARTGYYTNTCNTCNATGATHGARGCNGCNGCNGGN CARCAYCCNGAYATHATHAAYGTNCCNYTNAGYGTNGAYYTNACNYTNAAYTGGATHYTN GAYGTNTAYGAYAGYGTNMGNAGYGGNAARATHMGNGTNYTNTCNTTYAARGTNGCNGTN GTNYTNYTNTGYCARGCNCARYTNGARGAYAARTAYMGNTAYATHTTYMGNYTNATHGCN GAYGCNAAYGCNTTYGCNGAYCARMGNAARATGGGNYTNYTNYTNCAYGAYTGYATGCAR ATHCCNMGNCARYTNGGNGARATHGCNTCNTTY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AGYMGNGTNAAYMGN GCNGTNGAYTAYYTNCAYYTNTGGAARAARGAYMGNAARTCNTGGAARTTYAAYAARAAY TTYCARACNYTNYTNATHAARGCNGCNTAYAAYCCNATHATHATHACNGARGAYGAYTTY GARACNYTNYTNYTNTAYYTNGARGARTGYAARGGNTTYGCNMGNGARAARYTNMGNACN ACNGCNATGGCNYTNATHAARGARGARGARGAYGCNGGNYTNAARYTNGCNTAYATHGAR GGNTGGAARYTNATHAAYYTNGCNAAYGARYTNTTYGGNTTYACNGGNTGGTCNCAYTCN AGYAGYAGYCARACNGTNGAYTTYGTNGAYCAYGTNAAYGGNAARTAYTAYGTNGGNGTN TCNGCNACNGTNMGNGTNACNYTNAARAGYGGNGTNTAYCAYGARGAYGTNGGNTAYGGN GTNAGYGARGGNATGMGNTCNAARGCNYTNTCNYTNGARAARGCNMGNAARGARGCNGCN ACNGAYGGNYTNAARMGNGCNYTNAARAGYTTYGGNAAYAGYYTNGGNAAYTGYYTNTCN GAYAARGARTAYYTNAARTGYATHAAYMGNGCNCCNAARCCNACNCCNCCNGCNTAYAAY GTNGAYGAYATGAARMGNGGNCCNGARGAYACNYTNGTNTTYAARGCNMGNATGGCNGCN CCNATGGAYAAYAARTCNTAYYTNCCNTGYGAYGAYTTYATGAARTTYCARGAYGCNYTN AARAARYTNMGNYTNATHGAYGAYMGNGTNATHTAYGCNYTNAAYAARAAYATHCCNACN CARTCNTTYCAYGGNCARGTNGAYGTNGCNTCNAAYTGYMGNCAYATHTAYGAYGAYATH CARACNTCNTAYAGYCAYMGNGARAARTCNATHCAYCAYTGYATHMGNYTNGTNAGYGAR GAYGTNAARAARYTNAAYGARAARMGNCARCARGAYCCNGAYAGYYTNGAYGTNATGAAR GCNYTNMGNMGNGARCARACNAARYTNMGNYTNATGCARCARGARATGAAYGTNGARGAR GTNGTNAARGAYMGNACNYTNAARGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGN------------AARYTNTCNGAYTGYATHGAYGAY ATGACNGCNTAYATHCARGTNACNGAYAAYATHYTNTGGGARATHTAYATHTCNCARGAY CCNGARYTNMGNCCNGCNAARGARATHGTNAARMGNYTNTTYTGYMGNGAYYTNTAYMGN TGYYTNGAYGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNGCNYTNYTNGCNGTNGTN--- ---ATGTCNAARCCNGTNAAYMGNAARCCNCAYCCNACNGAYCCNGTNGARGGNAAYTCN CCNGAYAAYAAR---GTNGAYCCNACNGGNYTNTCNTAYGARCAYTAYYTNAARGARGTN GTNGAYGTNYTNGARAGYGAYCCNGARTTYAARAARATGYTNGARACNGCNAAYATHACN GAYATHAARAGYGGNAARATHGCNATGCAYYTNGCNYTNGTNAAYCAYACNGTNMGNGAY GTNYTNCAYGARYTNAARMGNAARGARYTNTCNMGNYTNTCNCARYTNGCNMGNATHCAR YTNAARTCNCARAARGGNGTNAARAARTTYGARATHCCNGAYCAYYTNGAYYTNGGNAAY CARCAYTCNTTYGARATHAARGAYYTNGARGCNYTNATHAARAARACNACNTCNGAYYTN GARAARYTNGAYGARCARMGNCARAARGARTTYAARGARTAYGARATGGARAARAARTTY GARCARGARCARCAYYTNAARGARYTNAARGARGARGAYMGNAARAARGARGARGARCAR YTNGARGARYTNAARAARAARCAYAARGAYCAYCCNAARGTNCAYCAYCCNGCNAGYAAR GAYCAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CARGCNATHYTNGCNAARYTNCAYCCNCAYGTNCCNAGYTGGGGNTCNYTNYTN MGNYTNTAYGCNACNAAYGTNGARAARCCNATGGARAARGTNGARGARATGAAYGARATH AARACNCARGTNCCNAAYCARGCNGTNYTNGARAAYYTNMGNGARGARATGAARAARYTN CAYMGNCARAARGARGCNATHCARTCNAARGGNAARATHYTNATHTGYACNAARGAYYTN CCNAGYAARATGTCNTGYGTNGAYYTNATGGTNGCNTTYGGNYTNCAYYTNGGNGCNTGY TCNGCNTGYYTNGCNATHCAYMGNGAYGGNAARACNGARGTNGTNGCNAAYGAYYTNGGN GAYMGNGTNACNCCNGCNGTNGTNGCNTTYACNGAYCAYGAYATHTCNYTNGGNGCNGGN GCNAARCARGGNACNATHMGNAAYGCNTCNAAYACNGTNGCNCAYGTNAARCAYATHATH GGNAGYAAYAGYGAYGAYCCNCARGTNCARGARTAYATHCARAAYCAYCARGTNAAYGTN GGNAAYCARAAYGGNTCNGTNGTNTTYAAYGTNGARCAYYTNGGNAARAARGCNCARTAY ACNCCNAGYAARATHYTNGARYTNATHTAYGGNAARATGYTNGARACNGCNCARAGYCAY AGYGGNAGYGGNACNAAYGAYACNGTNYTNGCNGTNCCNTCNGAYTTYACNCARCARCAR MGNAAYYTNYTNAGYGCNGCNGCNACNAARGCNGGNTTYAARGTNYTNMGNGTNATHAAY GARCCNTCNTCNGCNATGYTNGCNTTYGAYGTNGGNCARTTYGAYGARACNGARCAR--- TTYAARACNYTNGTNTAYMGNYTNGGNGGNACNTCNCAYGAYGCNACNYTNGTNAGYGTN CARCAYGGNATGTAYTGYATHYTNGCNAARGCNTCNGARAGYCARTTYGGNGCNGAYMGN YTNACNGARGTNYTNCARGGNTTYYTNGCNTCNGARTTYAAYMGNCARTTYMGNTGYGAY GTNMGNGARAGYAARMGNTCNATGAGYAARYTNAARYTNGCNGCNGARMGNTGYAARCAY TCNYTNAGYAAYYTNCCNAAYGCNCARTGYAGYGTNGAYTCNYTNTTYGAYGGNYTNGAY TTYTCNTAYAAYATGTCNMGNGCNMGNTTYGARAGYYTNTGYACNCCNYTNATGGCNCAR TGYACNCARYTNGTNCARCARYTNYTNAAYAGYGCNGGNTGYAGYAARGAYGARGTNTCN AARGTNATHYTNTGYGGNGGNGGNACNAARTCNCCNATHGTNAARMGNGTNATGACNGAY TTYYTNCCNTCNTCNTCNYTNYTNAAYTCNATGCCNGARGAYGARATHATHGCNATHGGN GCNGCNAARGARGCNGCNYTNYTNGARGGNGAYGARGARGARAARGTNAARATGCARGAR GARAARAGYATHATGTTYMGNTCNYTNTCNAARGCNATHGGNYTNMGNGTNAAYACNCCN GAYATHCARGTNATHYTNTCNCARCAYTGYYTNATHCCNGCNMGNMGNCARCAYACNYTN ACNYTNCCNTCNTCNCARTCNAGYGTNATGYTNGARGTNYTNCARGTNCARGARCCNGTN ACNTCNGAYGCNGARGCNCARGTNYTNGCNAARATHGTNYTNMGNGAYYTNCCNCCNGGN TCNAGYATHAARTCNAGYTTYCAYYTNACNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GTNAGYGGNMGNGTNTTYMGNAGYGTNAGY GAYYTNGGNAAYCCNGTNGGNGARYTNGTNMGNYTNGTNMGNGTNTAYTCNACNCCNTGG GARGARAARAGYGCNGCNYTNAARAARYTNCAYGARGAYTAYGARAGYAARCARMGNCAR YTNAAYATHGCNGTNMGNMGNYTNCARYTNGTNGAYGCNCAYTCNAARMGNGTNGCNAAR GARAARMGNATHATGAAYTGGGARAARYTNTTYTCNAARATGACNAGYGCNAARGGNCAY GGNMGNMGNTGGAARTTYYTNATHGARACNATHAARCARAARGCNAARYTNGGNYTNGAR CAYGTNCARGCNTAYACNCARAGYYTNGAYGAYTCNTCNGARTCNGARACNGARGARGCN ATHACNGARCARGCNGCNACNGTNGCNGTNGGNGAYGTNGAYGAYGTNAGYGARACNCAR GGNTCNCARGGNGTNGAYGGNACNGARGGNAGYMGN---------GARGARAAYGARGAR GAYGARGAYGARGARGAYGGNCCNGCNGARGGN---MGNGGNGAYGARMGNGARGAYATH GAYTCNMGNGCNAGYGARGARTCNGCNCAYTCNGARGGNGAYCARACNGAYGAYATHCCN ACNGTNTCNGTNCAYATHGGNCCNGGNGAYGAYGTNGAYATHGARGGNAGYTCNGTNMGN TCNGCNTCNCCNAARAARGTNMGNTTYGARGARTCNGTNGCNACNTCNAGYTAYATHMGN CCNCCNATGTGYGAYACNACNACNTGGACNGGNCARCCNGAYCAYGAYMGNTTYYTNTTY ATHMGNATHTTYTGYCCNGARGGNYTNGARCARYTNGGNACNGGNATHAARTGYTCNYTN TCNTAYGAYGGNAAYATGTTYAARACNCCNGTNYTNGAYYTNCCNGARGAYGGNGCNTCN GARGCN------ACNGARGARAGYGAYGARMGNCCNAGYCARMGNCCNCARGCNGCNMGN AARTCNGARGGNMGNTCNAAYGCNGAYGTNACNCARGARACNGAYTCNGCNAARGCNAAR TCNAARAARCAYTTYGARTTYGARATHCCNYTNCCNGAYGARYTNACNGARGGNATHYTN CAYYTNGGNGARAARCCNCCNCCNGARCCNGARAAYATHMGNATHGCNATHCAYCARGGN CARTTYGARGARATHATHGCNATGGCNACNATHGAYTTYYTNGAYATHAARGGNYTNAAY YTNGARACNGTNTGGYTNCCNGCNCCNGCNGGNGAYGAYGARGTNGCNGCNGTNAARTCN MGNTCNAAYTCNYTNAGYTGYACNTCNAGYYTNGGNGGNGARTCNYTNTCNGAYTCNATG GAYATHCCNATHATGYTNGAYGAY------GAYCARTCNGGNMGNGGNYTNGTNTCNTCN ACNCCNMGNGAYGARATGYTNAARACNAARGAYCCNYTNCCNTTYCCNYTNTAYCCNYTN CAYGGNGGNAARACNGAYTCNYTNCAYGTNCCNTGYGGNAAYGTNCCNYTNTTYATGTAY TGGGGNAARMGNCCNMGNCCNGTNACNTTYAAYMGNCARTGYGGNACNYTNGGNATHTAY GAYATHGTNTAYGAYATHACNGGNTTYGAYATGACNACNACNTCNAARGARGAYYTNCAY AARGARATGGTNGAYGARGCNYTNTCNGTNGCNGCNTTYACNCCNGAYCCNGCNGTNGAR GAYAARTCNACNAAYATHGARGARACNATHYTNAARTCNGARTAYGAYAARYTNGTNCAR ACNCAYCARGARGARATGATHTAYYTNCARGARGARTAYGARAARMGNYTNCARGARYTN GTNCARAAYTTYCARACNATGCARGCNGARAAYGARCARYTNCCNCARYTNATHTCNCAR CARTCNTCNCARCARMGNCCNYTNTCNGTNGCNTCNMGNGTNAGYACNACNCCNGGNGCN ATGACNCCNATHACNTCNAARMGNTCNGARMGNTCNGAYCCNTCNTTYTAYGAYAGYGTN ---YTNCCNCARACNGGNCARAGYATGMGNACNATHAGYMGNAAYAARTCN---AGYGCN GARATHGAYMGNGARAARAGYATHATGTCNCARAGYACNACNAGYACNMGNYTNAARCCN YTNCCNCCNMGNAAYATGAARCCNGCNAARAAYTTYMGNATHGGNAARCCNYTNCCNMGN TGGGGNGARACNYTNCCNCARGAYTTYTTYGAYMGNYTNMGNYTNTGGGARGARGARAAR MGNCARCAYAARCARGARYTNAAYGARAARACNYTNAAYGAYATHAARYTNAAYYTNGAR AARAARYTNGCNGGNCARCAYAARYTNAGYAARMGNGARGARCARATHTAYGAYGCNYTN AARGAYGTNAGYYTNCCNGCNYTNTTYATGCCNTAYAARACNGGNAAYATHTTYAAYCCN MGNGCNCAYCARTAYTTYCAYCCNACNGGNTCNTCNGAYGTNMGNYTNACNCARCCNCCN TCNGTNTTYAGYYTNCCNCCNYTNCCNAAYAGYAARYTNTCNGTNGTNAAYYTNTTYGAR YTNAGYAARAAYTTYMGNAAYMGNGGNCCNGCNTGGYTNGTNGARMGNTAYATHCARCAR CARCARCCNTCNCAYGARGAYTAYCCNCARACNCCNGCNCCNACNTCNGCNATGCCNCAR GTNACNACNACNTCNGGNGARACNCCNATHAAYGARAAYGTNGCNACNCCNACNAGYCAR MGNAGYATGCARCCNGARYTNGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ACNACNCAYYTNTCNATHTAYGAYGGNCARGARACNCARAARYTNAGY TCNTTYGAYTGYCAYAGYAAYCARAAYGTNAAYMGNTTYCAYYTNGTNACNAGYGGNGAY ACNGTNTCNTTYATGATGAGYMGNAAYAAYCCNGARAAYCARGAYTTYGAYATHGARATH MGNGTNAARCCNATHMGNGGNGGNATHTCNCCN------GAYAARGAYMGNTTYAAYTAY TTYAGYTTYCARAARTTYGAYCARGAYGCNATHGTNGGNATGATHGGNGGNTTYTAYGCN YTNATHATHATHATHTGYATHGTNGTNGGNTAYTGYAAYTTYMGN---TAYMGNGGNATG AAYAARAARTGGGARACNCAYCARYTNGCNACNATGAARACNGAYACNACNTTYGAYGCN MGNAGYCARGTNTCNCARCCN------CCNTGGTCNGTN---GCNAGYCARAGYMGNGAR CCNGTNAGYCARTAYTCNMGNTCNTAYACNGARCCNTTYTCNMGNMGNGGNGCNACNGCN MGNAGYGAYGAYGGNTCNAGYGTNGTNTAYGAYCAYGAYGARAARTTYCARCARMGNAAY YTNATGMGNGAYGARMGNGAYMGNCAYMGN---GGNMGNGAYMGNATGGCNTCNCARAAY ACNACNTAYACNGAYCARGARGAYCCNGAYAAYTTYAARGARAARGTNATHACNCCNMGN GTNAARACNTCNMGNACNMGNGAYMGNMGNCCNCCNTCNTTYGARGARGCNACNMGNGAY AGYTCNATGGARGGNTCNTCNGAYGARGAR------ACNGARGARTCNAGYGAYGAYTCN ACNMGNAARMGNYTNACNACNTCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CCNGARGGNTGGGARAARTAYTCNAAR ATGGGNAARGTNATHMGNGGNACNACNATHATGCCNATHAARGTNCCNYTNMGNGARAGY YTNACNAGYTCNYTNCCNCAYGARGARMGNTTYTCNCCNTCNATGYTNYTNGARYTNTGY CARCARAARGGNYTNAARYTNGGNGGNGTNGTNGAYYTNACNAAYACNACNAARTAYTAY GAYGGNAAYTTYTTYTCNCARAAYGGNGTNAAYTAYAARAARGTNTTYACNCCNGGNCAY GTNATHCCNGAYAAYAAYATHTAYAARCARTTYGARAGYGCNATHAARGARYTNGARAAR AAYGGNTTYATHACNTGYGTNCAYTGYACNCAYGGNYTNAAYMGNTCNGGNTAYATGATH TGYMGNTAYATGATHGARGCNYTNAAYATHGARCCNCARACNGCNATHMGNYTNTTYGAR GARGCNMGNGGNCAYAARATGGARMGNCARAAYTAYATHGARGAYYTNMGNMGNMGNAAY CCN---------GGNCARGCNGGNGAYMGNATGAGY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AARCAR TCNCCNGGNGARGAYATHTAYAARGARGGNGCNGCNCCNGTNTTYGARGARYTNACNAAR ATGMGNCARATGATGACNYTNAARMGNCCNAARGGNTCNACNYTNMGNYTNGTNTGYAAR GCNAARGGNAAYCCNCARCCNCARGTNCARTGGTAYAARGGNTCNGARYTNTAYAAYCAR MGNMGNCCNCAYTCNACNYTNAARATHCAYGGNGTNACNGGNAARGAYAGYGGNMGNTAY ACNTGYGTNGCNAGYAAYMGNYTNGGNCARACNAAYTTYACNTAYGGNGTNCARATHATH GAYGARATHAAYCARCCNAARYTNATHGCNCCNCAYCCNYTNAAYAARACNGTNTAYATH GGNGAYTCNGTNTCNTTYCARTGYTAYATHGARAGYGTNGTNGARCCNGARGTNAARTGG YTNAARMGNGTNGAYAAYCCNGARACNTAYTCNAAYCCNAAYGTNACNYTNTTYMGNTAY AAYAARCARACNYTNATGGTNYTNGARGAYGCNGGNATHYTNCARGCNMGNMGNGAYGGN TCNTAYYTNAAYAARYTNGTNATHAARTCNGTNMGNCCNCARGAYGCNGGNATGTTYGTN TGYYTNGCNACNAAYMGNAARGGNTTYGTNAARMGNCARGCNTTYYTNCARGTNMGNGAR GGNTTYTCNGGNAARGGNTCNTCNCARGAYTCNTCNTCNTCNGAYTCNCAYAGYTCNTCN CARTCNTCNGAYGAYACNAAYYTNCCNYTNYTNATHGGNYTNCCNGCNTGYGCNYTNYTN ATHATHATHYTNATHACNGTNTTYYTNYTNCARMGNAAYAAYMGNTGYAARMGNTCNAGY ACNAAYACNAARGTNCCNMGNACNCCNGTNCCNCCNACNGARMGNGARGCNTAYTAYTAY AGYAAYTGYCARCARCARCAYYTNCARCARTCNATHAAYCCNYTNYTNATGTCNMGNGAY AARYTNCCNAARACNCCNACNCCNTCNGTNGAYATGACNGGNTCNGARTTYTCNTCNGTN TCNMGNACNCAYCCNCCNCCNCAYCAYCAYAAYAAYCAYAAYTAYGGNTAYGGNGGNMGN GCNAGYCCNATGTCNGARACNAGYMGNAGYTCNAGYGGNAGYCCNACNCCNAGYGAYACN AGYTCNCARAAYGCNGCNATHAGYCARCARGCNYTNAAYGCNGCNATGCCNATGAARAAY GARGARACNTCNAARYTNACNGCNTCNYTNAGYAAYTAYTAYAAYGARTCNYTNATHGGN CAYGTNYTNGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GAYMGNGCNTGYGCNTGYMGNGGN YTNAAYCCNGARGGNGTNGTNMGNAAYGCNAARYTNTCNTAYYTNAARAAYTGGACNGAR ATHACNACNGAYGTNCAYGARCARAGYATHTCNYTNYTNYTNCAYYTNCCNATHYTNATG GCNTAYTGYCARCCNTCNAAYMGNAARYTNATGGGNCAYCAYCAYCAYGCNGAYGAYCAY TGYCAYYTNTCNGCNAARTAYGCNGARTAYGTNGARATHMGNYTNGAYGAYYTNMGNTCN AARTGYGAYCARYTNACNGARTGYATHAAYGARYTNYTNTCNCARYTNAGYTCNATHTCN GTNYTNMGNGGNGAYGAYYTNAGYATHMGNAARATHTGYAAYYTNATHAAYATHAARGGN AAYAGYACNAARGCNATGYTNCAYGGNAARTGYTCNYTNAGYGARMGNMGNGAYATHATG GARTAYGTNGAYAAYCARYTNAARGAYAARYTNGARAARMGNAAYAGYTGGGARAAYGTN GCNGCNTGYYTNGARGGNAAYTAYGGNGAYAAYGARMGNACNACNAAYGTNGGNGAYATH TGYGGNYTNGCNGARAARTAYGARGARATHTGYAARAAYTAYGAYATHCAYAARCARGTN GARAARTAYGTNAAYGARCARATHGARCAYYTNCARTGYACNTGYAARGCNYTNGCNMGN GAYTCNGCNCAYACNCAYGARCAYATGTCNACNAGYACNATGGTNGGNATHGGNGTNGGN GGNGTNYTNYTNYTNTGYYTNATHGTNYTNGGNYTNGTNTTYTTYTTYTGGMGNMGNAAR YTNAARMGNAARAARAARTCNMGNCARAAYATHATHTAYYTNCCNGCNGCNGGNCARGAY AAYTGYCCNGTNTAYCARGARATHTTYGAYCARMGNTCNCCN------------CCNYTN AGYCCNCCNTCNYTNCCNMGNTAY------------GGNTCNMGNCCNYTNCCNGGNCAY CCNCARGARGARGCNGARTAYYTNGARCCNGTNCARGCN---------CARGCNGCNTCN AARGCNCCNCCNCCNYTNCAYMGNACNGTNAAYAAYCCNGGNTAY------GARGTNGAR GCNCCNCCNAGYTAYACNGARACNGAYCARYTNTAYGAR---------------GAYGCN ATHYTNATGGARGCNGAYGGNAAY---GCNTAYTTYGARCCNATHGTNACNCCNAARACN GARGCNGCNGARAARCCNCARGARGAYGAYTCNAGYGAYACNTAYCARCCNYTNGARGAY ATHGAYACNAAYAARCCNYTNGGNCCNGAYCCNGCNGARMGNACNAARAARGARGAYMGN CARACNGARTCNGARTAYTTYGARYTNGAR------------------------------ ------------------------------------------------------------ ---GARMGNAARTAYGAYTTYGCNCCNAAYMGNCAYGGNMGNGGNMGN---MGNCCNACN TCNAAYGGNGGNACNAARGCNCARGAYGTNGTNCARAAYCCNMGNCCNGTNCCNATHAAY AARTGGGAYMGNTCNGTNGGNGAYMGNMGNCARMGNCARMGNAAYTGYTAYGAYTAYMGN CARMGNGARGARGTNGTNGARMGNGAYGAYGTNYTNGAYGTNYTNAGYACNGGNTCNMGN AARGGNAAYGCNAAYCAYYTNYTNAAYTTYTTYTAYCCNMGNCARAGYCARGGNGAYGAY CAYMGNTGGTAYGAYMGNAGYTGYTTYAAYTCNMGNGGNMGNGGNGGN------TAYAAR AARACNAARMGNTAYAARAARGARCARTTYYTNCARGCNAGYTGYCARTTYGTNGTNMGN GAYACNGGNGAYTAYACNGARCARGCNATHAAYTCNGAYGCNYTNGTNGAYTGGAAYATG ATHGARYTNGTNMGNAGYTTYTCNACNGARCCNGTNAAYTGYCCNATHTGYYTNCARGTN CCNTCNGCNGGNAARATHACNAARTGYGGNCAYACNTAYTGYTGGGCNTGYATHYTNCAY TAYYTNAARYTNGGNCARGAYGAYGCNMGNAARTGYCCNATHTGYTAYGAYGCNGTNGAR GARGAYGAYYTNAARAGYGTNCARTGGATHGAYGTNCCNAAYTTYTCNGTNGGNGAYGAR ATHGAYATGMGNYTNATGAARAARGCNAARGGNAGYATHATHGCNYTNCCNAARTAYCAR TGGGARGAYMGNCARGGNMGNCCNATGAAYATHCARGAYGGNGTNAAYACNAARTAYATG AARYTNYTNGTNGCNTCNTGYGAYCARATHCARAARGARGTNATHGARATHGARMGNGTN GCNYTNACNGTNCARYTNGAYGAYGCNGARGARTCNGARGCNTGYTTYATHCAYATGGCN YTNGARTAYYTNAARGCNMGNGARCARTCNYTNAARCARCARMGNAGYCARACNAARGAY AARTCNAGYATHCCNGGNYTNGGNTCNACNGAYGTNTAYAARGCNCARGARMGNTCNTCN GAYGAYAAYAARTCNCAYACNACNGCN---------ACNATHTAYGCNGAYGCNTTYGAR ---------------------------------------------------GARGARATH GCNAARGTNTAYGARGAYGARAAYAARYTNGARAAYGARACNTCNGAY------------ ------------------------------------------------------------ ---------------------------------------------------TCNACNATH ATHGARTCNGTNTCNACNMGNGARMGNAAYGAYAGYGARTGYTCNYTNCCNTTYGGNTCN CCNACNTGYCCNTTYCCNYTNGTNCCNGAYCARGARGTNAAYTCNGTNCCNYTNAGYYTN GARGARACNGCNGAYCAYYTNGARYTNCCNATHGAYCCNCARGCNATHAARCARCARTCN AARAARTCNAAYAGYYTNAAYACNAARGAYACNTAYTTYTTYTAYCARGCNTCNTCNGGN CARCAYATHTAYYTNAGYTCNYTNAAYGCNCARTGYYTNGCNAARGARTAYGGNTCNYTN GARGARAGYCCNAAYACNATHAARGCNACNATHGTNGCNATHGARMGNATHTTYATGACN GARGAYGTNMGNAARMGNYTNMGNTAYYTNGAYCAYATHCCNYTNACNTGYGARATHCAY GTNGTNGARYTNAARATHAARCCNCCNGTNGTNAGYAARGARACNYTNAARTTYTTYGAR GCNTCNTTYGAYMGNAARMGNAARYTNMGNCARCARAARGARAARGARGAYAARMGNMGN GCNMGNAARTAYGARATGGARCAYAARAARAGYTTYGGNATHTAYCCNGARGTNCARATH CCNYTNGAYAAYTTYACNCARTTYCCNTCNCAYYTNTCNGCNAGY--------------- ---GTNAAYGAYTGGYTNAARMGNTCNTAYAAYATHAAYGTNACNGAYGAYTGGYTNTCN ACNTGYATHGARTTYATHMGNCARGARACNCARGAYTCNCAYCCNAAYYTNGARGARYTN AARMGNYTNGTNTTYGARCARTGGYTNGTNTCNGAYYTNTCNGARATHGGNAARCCNYTN ATHCCNGGNGARGTNTTYACNTGYGARAARTGYCAYTTYCAYCAYGTNTAYCCNYTNCAR ATGATHTCNATHGTNGAYGTNGCNACNCCNYTNTTYGGNCARATHCARAARTTYCARGCN TCNGAYAAYCCNTTYGARTCNCAYAAY---AAYCARACNTAYGGNAAYAAYAGYACNAGY TAY------------------AARYTNTCNMGNATGYTNAARATGGARYTNTCNGAYGGN CAYMGNAAYATHCARGCNATHGARTAYMGNCCNATHAARTGYYTNACNGCNGAYYTNCCN TCNGGNACNAARATHYTNATHAARGGNTCNATHGTNTGYMGNMGNCARGTNYTNYTNYTN CARGARGARAAYATHTGYGTNATGGGNGGNGARGTNGAYGAYYTNATHGTNGTNAAYAAY CCNYTNATGAAYYTNCARGCNGARATGGARMGNAAYMGN--------------------- ---------------------------------------------------------MGN TTYMGNGARGAYATGGGNGAYGARGAYCARATHAARAAYAAYAARCCNCCNACNGCNCCN ACNAAYATGGTNYTNTTYTAYACNTGGATGATHYTNGCNATHYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYTGYGTNACNTTYATGGARGARAAYTTYYTNTCNTTYYTN TGYGTNAARCARCCNGTNCAYYTNGARCAYYTNGAYATHTCNGGNTGYTGGAAYATGGGN GAYGAYATHYTNATHAARYTNGTNCARMGNTGYCCNAAYYTNAARCAYYTNATHYTNGGN AAYYTNTAYGGNYTNACNGAYCAYGCNGTNTGYGCNATHGCNCAYTCNTGYCCNAARYTN YTNACNYTNAAYYTNTTYGGNTGYTGGMGNATHAGYGAYGCNTCNATHAGYYTNATHTCN GCNTAYTGYACNCAYYTNAARYTNYTNGARATHACNCARTGYMGNGAYGTNACNGARCAR AGYYTNGGNCCNYTNMGNAARMGNYTNGTNAARATHGAYAARCCNGCNCCNCCNTCNTCN TAYCCNAGYMGNYTNGARTTYGTN------------------------------GAYAAR GTNGTNYTNTAYGGNTAYTTYMGNAGYTCNTCNAGYTGGMGNGTNMGNATHGCNYTNGCN YTNAARAAYATHAARTAYGARTAYGARGCNGTNCAYYTNYTNAARGGNCAYCARAARACN GARGARTAYAARAARYTNAAYCCNAGYGGNTTYGTNCCNACNYTNAARATHGAYGGNCAR ATHYTNACNCARTCNATHGCNATHYTNGARTAYYTNGAYGARACNTAYCCNGAYCCNCCN YTNYTNCCNAARGAYAARGCNGCNMGNTCNCARGTNMGNGCNATHGCNGARATHGTNAAY AGYGGNATHCARCCNYTNCARAAYYTNAARATHYTNCARAARATHGGNGARACNAARATG GARTGGGCNAAYCAYTTYGTNACNGARGGNYTNATHGCNATHGARGCNATGYTNGARAAR ACNGCNGGNACNTAYTGYTAYGGNGAYGARGTNACNATGGCNGAYYTNTGYYTNGTNCCN CARGTNGCNAGYGCN---GCNMGNTTYAAYGTNGAYATGTCNMGNTTYCCNATHACNGCN MGNGTNAAYAARGCNYTNGARGARYTNCCNGCNTTYAARGTNGCNGAYTTYMGNMGNCAR CCNGAYACNCCNGARGAYYTNAARATHGARATGGARAAYGCNGAYCARACNGTNYTNTCN YTNTGYAARGARGTNTGGCARTGGMGNYTNGCNGARAGYCCNGARYTNGCNACNTTYTGY GGNTTYTAYCARGAYGAYGAYAARTGGGAYGAYATHAGYGARGARGCNTAYGGNMGNMGN GARGGNAARGTNATGGARTTYYTNAARGCNGCNGARGARYTNGAYGTNAARGAYTGYAGY CCNGAYGTNGTNYTNAGYTAYMGNYTNYTNGTNTGYGAYYTNAARACNTAYATHGARGGN ATHCCNTAYAARAGYTAYYTNATGCCNYTNAAYTAYYTNGARGGNATHCAYACNGAYTGY AAYYTNATHATHTCNTAYATGAARTTYGARGARGARAARGAYTAYGTNGTNYTNAARTCN MGNYTNGARAAYTTYCCNTCNMGNATGCARCARGTNATHACNATGYTNAARAGYGGNATH GARCARGGNATHGCNAAYCCNAARTAYTCNATGCARGAYATHCCNGGNCARATHGAYATH ATHYTNTCNACNCCNGTNGARGAYTGGGGNYTNATHAARCCNTTYAARGARAAYGTNTCN AARATHTCNCCNGARGTNTTYCARAARYTNAARACNCARTGYTCNGAYATHATHCARTCN TCNATHATHCCNGCNTTYAAYGARYTNAARACNTAYATHGTNGARGARTAYYTNAARAAY GTNMGNCCNCAYGCNGGNGTNAAYACNYTNCCNAAYGGNAGYGARTGGTAYCARCARTGY YTNAAYTTYCAYYTNACNTGYTCNATGACNCCNCARGARGTNCAYGARATHGGNYTNAAR GARGTNAGYMGNATHAAYTCNCARATHGTNGCNYTNGCNAARAARGARGGNYTNCCNGAR ACNATGCCNGARYTNYTNGARGCNATHGARAARAARCARGCNAAYTCNTTYMGNTCNCAR GAYGARGTNYTNGARTTYGTNAARGAYYTNTGYTAYAARAARATHMGNCCNAARATGAGY AAYTAYTTYMGNGGNYTNCCNGAYATHCARATGAARATHGTNYTNTCNCCNTCNTAYTCN GCNTCNGCNCCNCARGGNTAYTAYYTNAAYGGNACNCCNGAYGGNTCNMGNGAYGGNTCN TAYTTYATHAAYGCNAAYAAYYTNCCNTCNTGYYTNCCNTAYAGYYTNCAYGCNYTNAGY YTNCAYGARGGNGARCCNGGNCAYCAYYTNCARGCNATHTAYTCNYTNGCNGCNACNAAY YTNCCNGAYTTYMGNMGNTAYTGYGARGAYAGYAARTAYTAYYTNTCNCCNTCNAARTTY TCNTTYAAYACNGCNTAYATHGARGGNTGGGGNYTNTAYTGYGARGCNYTNGGNGARGAR ATGGGNATHTAYTCNGAYAAYATGGARYTNYTNGGNMGNTAYAAYATGGARATHTTYMGN GCNGCNMGNYTNGTNGTNGAYACNGGNYTNCAYGCNTTYGGNTGGACNAARGARAARGCN GTNGAYTAYATGAAYACNCAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGTCNGAYAARYTNAAYACNMGNGTNATHCARGTNACNAAY ATHGCNCCNAGYTGYACNAARGARCARYTNMGNACNYTNTTYGGNTAYYTNGGNMGNATH AARGARYTNGARATGTAYCCNCCNGAYGGNGCNGAR---GGNGTNGTNACNGCNMGNGTN GCNTAYATHGARTTYGARGAYTCNGTNACNACNGGNGTNGCNYTNCAYYTNAGYAGYACN GTNTTYATHGAYMGNGCNATHATGATHGTNCCNGTNATGGAYGGNAARATHCCNGAYGAR AGYTCNGCNYTNCARYTNACNCCNTCNGCNGTNGCNGGNATGYTNCCNGGNCARCCNACN TGGCCNGCNAAYGTNGTNTCNCARGTNACNGGNYTNGGNGCNAAYCARATHATHATGACN AAYGAYCCNMGNYTNACNTCNYTNGGNYTNCCNCARTAYCCNCCNYTNCCNGCNACNACN GAYCCNAGYAARATHGARGARATHMGNMGNACNGTNTAYATHTCNGAYYTNGAYGCNAAR GTNACNCCNGARATGYTNYTNTCNTTYTTYTCNCARACNGGNGARATHAARTAYATHMGN ATGGCNGGNGAYGARAAYGCNCCNACNMGNAGYGCNTAYATHGARTTYACNGAYCARMGN TGYATHGCNCARGCNYTNAGYTAYAAYAAYGTNGTNTTYCARGGNMGNACNGTNAGYGTN AARCAYGCNACNACNAGYATHGTNAARCCNACNCCNMGNTCNGARGCNTCNCARMGNGAR ATHGAYGAYGCNATGAARAARGTNAARGARGCNTCNAARYTNATHTCNGCNGCNGCNAAY AGYGAYMGNGAYGGNTCNMGNTCNCCNACNMGNAARMGNTCNMGN------TCNAARGGN MGNAGYMGNTCNCAYTCNMGNCCNMGNMGNTCNMGNTCNMGNTCNMGNGTNCAYMGNMGN MGN---AGYMGNTCNMGNNNNMGNMGNNNNTCNMGNTCNMGN---MGNTCNCCNMGNMGN NNNMGNTCNCCNNNNMGNMGNMGNMGNTCNMGNNNNMGNNNNMGNNNNCCNCARCCNGCN CCNNNNNNNMGNMGNTCNMGNNNNNNNNNNNNNNNNNNNNNNMGNNNNMGNTCNNNNNNN MGNNNNMGNMGNNNNMGNNNNMGNNNNMGNTCNAARACNMGNNNNNNNMGNNNNNNNNNN NNNTCNNNNNNNNNNMGNNNNNNNTCN--------------------------------- ------------------------------------------------------------ ------NNNNNNNNNNNNGANNNNNNNAARNNNNNNNNNNNNNNNNNN------NNNMGN NNNNNNNNNCCNNNNNNNNNNAARAARMGNAGYYTNACNCCNAARMGNMGNAGYMGNTCN MGNTCNCCNAGYMGNMGN---AARAARMGNMGNCAYTCNMGNTCNACNTCN---MGNAAR MGNTCNMGNTCNMGNAGYGGNTCNMGNCAYMGNTCNMGNMGNGAYMGNAARMGNAGYMGN AGYMGNGAYMGNAARCAYGAY---AGYAARAARAARAGYAGYMGNGAYAARGARGAYMGN AARAARGAY---AGYAGYAGYTCNAARATHAARMGNGAYTAYGAYGARGARGARAARGGN TTYGCNAGYGAYMGNAGYGAYGAYMGNGAYAAYAGYGARGARGGNMGNGCNGARTCNCCN AGYGGNCCNCCNCCNYTNYTN---------GARAARGAYACNGAYAAYCARCCNGTNGAY ATGGAYATGAGYGAY------------------------------------------GGN TCNCAYAGYAAYGTNYTNGAYAGYCCNGGNGARGAYATHGARTTYATGGAYAARMGNAAR AGYATHATHAARTAYCAYGGNAGYGARGGNYTNYTNAAYYTNCARTGGYTNGCNGARCAR ACNGCNAAYGCNAARGCNTTYGAYTTYGARATGGAYGARCAYTCNATHTCNACNMGNMGN CCNGAYGGNCARGTNGARACNACNGTNACNGCNACNMGNACNYTNATHYTNCCNGGNYTN GGNGARGARGARGARGAYGAYCAYGAYGGNATH------ACNGARAAYGGNGARAARGAR ---CARATGMGNGARGARATHTAYGGNAARATHGCNCARAARYTNATHGARATGGCNGAY ACNTAYAGYGCNAGYYTNTCNGAYGCNGAYGAYYTNTCNCCNGTNGCNYTNGGNGAYGCN CCNYTNACNGAYYTNGARAARGARATHATHGCNTGYYTNMGNTCNGGNGGNGAYAARTAY GGNAARATGATGGARGAYCARYTNGAYGCNYTNAARTCNGCNGTNACNGARGAYGCNTAY GGNMGNTTYMGNAGYACNGTNGARAAYTCNATGGGNCAYGARYTNAGYTGGAAYACNYTN GCNYTNYTNTTYTAYGCNACNAARGGNGTNGTNTCNGCNGTNGGNAARAGYTCNAARGTN GCNGTNCARGCNAARGARTTYACNYTNCARTAYATHAGYGAYACNTTYGTNTCNTGGATH ATGGARCARGGNGGNTTYGAYAGYATGYTNAGYGGNAGYGAYTCNGAYCCNGARYTNGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CAYYTNTGYATGATHAGYCCNCCN CARMGNGGNCCNATGACNAGYATHAAYAARCCNGGNTCNCCNGARTGYATHYTNYTNAAR TCNCCNTGYGGNGGN---TCNCCNAARAAYGCNGTNYTNGARYTNMGNGCNGGNCARAAR TAYACNGTNACNYTNATHAARAAYYTNGAYCAYTTYAAYAGYAARGCNCCNGGNAAYTTY ACNGTNTCNATHGGNMGNAAYGTNGAYTCNYTNAARCCNYTNACNACNATHCCNGAYACN TCNGAYGGNTCNYTNACNATHTAYACNGCNAAYGTNACNATGCCNATGGARCAYGGNGAR ATGGTNYTNCARTCNYTNTAYAAYACNAAYAAYCCNCARGCNCCNCCNGTNTTYTAYCAR TGYAGYGAYYTNMGNYTNGTNGGNMGNGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGNATGGGNCAYATGGGNGAYGGNGGNTGGGARATHTGY GAYGAYGARGGNYTNMGNCCNMGNAARCARTCNTGYYTNGCNTAYTCNTTYGGNGAYGTN TCNGAYTAYGCNTTYGARGAYGAYGTNGCNMGNATHTAYAARTGYGARGTNCAYTCNTTY AAYCCNAAYYTNTCNGGNTCNGAYTTYAAYMGNTCNMGNYTNGTNTTYGTNCAYCCNTAY GGNGCNGGNMGNAAYTCNGARATHACNCCNAAYGGNAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARATHTCNCAY ATGATHGCNTTYATHGAYCARGARGCNTCNGARAARGTNGARGARATHGAYYTNAARGCN GARGARGARTTYAAYATHGARAARGGNMGNYTNGTNCARCARTCNMGNGTNCARATHATH GAYTAYTAYGAYAARAARGTNAARAAYGTNGARYTNCARAARAARATHCARAAYTCNAAY ATGCARAAYAAYGCNMGNYTNGARATHYTNMGNAARAARGARGARTAYGTNAARGARGTN YTNGAYGARGCNMGNGARCARYTNAARMGNGTNGCNAARGAYAAYCCNGARGARTAYAAR CAYYTNYTNYTNMGNYTNATHATGCARGCNYTNGTNMGNYTNATHGARACNAARGTNACN ATHMGNTGYMGNMGNGARGAYGTNCARATGATHAARAAYGCNGTNCCNAGYYTNGTNAAR GARTAYAARCARYTNYTNAAYGGNAARTAYACNYTNGARYTNGTNGTNGARGARGARAAR TTYYTNTCNCARGARATHTGYGGNGGNGTNGARYTNYTNGCNATGAGYGGNAARATHGTN GTNGTNAAYACNYTNGAYGARMGN------------------------------------ ------------------------------------------------------------ ---------------------------------------------AGYYTNATHACNTCN TAYGTNAAYMGNGGNGARAARAAYGGNYTNGTNTGYGCNYTNMGNMGNCCNGTNGCNCCN GARGGNGCNGARYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNATHGTNTTYATHCARMGNGTNGARTCNTTYAGY GCNTGYCAYMGNYTNCAYAGYCCNGGNYTNACNGAYGARAARAAYYTNGCNATHTTYGGN AARTGYAAYCAYCCNAAYGGNCAYGGNCAYAAYTAYAARGTNGARGTNACNYTNMGNGGN CCNGTNGAYCCNGAYACNGGNATGGTNATHAAYATHGTNGAYYTNAARAARTAYATHGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CARYTNCCNCARGGNATHCARYTN ATHAAYYTNCCNCAYCARCARATGTCNGGNCARTCNATHCARATGCCNGGNGGNGAYACN GGNGAYGARCCNYTNTAYGTNAAYGCNAARCARTAYCAYMGNATHYTNAARMGNMGNCAR GCNMGNGCNAARYTNGARTCNGARGGNAARATHCCNAARGARMGNCARAARTAYYTNTAY GARTCNMGNCAYMGNCAYGCNYTNAAYMGNGCNMGNGGNTCNGGNGGNATHTTYGTNGGN CARACNAARGCNGTNGAYGTNATHYTNGTNGTNGGNAARAAYAARATHCCNGTNAGYYTN AAYACNTCNCARTCNCCNYTNGCNGAYAGYTAYYTNACNGTNCARCAYYTNTGYGAYGCN GTNCARCARCARACNAAYATHAARCCNCARTCNCARAARYTNATHTAYMGNGGNMGNACN YTNTTYAARAGYTAYGAYGCNGARGAYGARAGYYTNACNAARAGYYTNTCNTCNYTNGGN ATHAARAAYGGNGAYMGNATHATGGTNTTYGGNAARCCNTCNGCNGAYGARAARGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNACNAARGAYATHATH CAYGAYGARCARAAYATHAARACNAARATGGGNAARAARCAYAARCAYAARAARCAYTCN TCNTCNAGYAGYTCNTCNTCNTCNAGYAGYGARTCNTCNGAYGARGARTGGAARCAYYTN CCNAARCAYGARAARAARATGTGYAARAARTGGAARAARCARTCNAARAARGGNYTNGTN GCNCCNGGNACNYTNCCNCCNTGGAARGGNGGN------------CCNCCNATGAARGGN TCNAARAARACNAARGGNGGNCCNCCNGGNTTYCCNGGNCAYGGNTAYCARCCNCARCCN GGNTAYTCNGGNCARCCNGGNTAYCCNACNCARCARCCNGGNTAYCCNCCNGGN---TAY CCNGCNCARCARCCNGGNTAYCCNGCNCARCCNGGNTAYCCNGGNCARCARCCNGGN--- TAYCCNGCNCCNGCNTAYCCNGGNGGNTTYCARCCN------------TAYCCNCCN--- ------------------------------------------------------------ ------CCNCCNGCNGCNCARTAYGCNCCNCCNCCNGGNGCNGCNTAYGGNAAYCAYGGN GCNCCNTCNGGNCCNTTYCARGCNCCNCCNGGNGGNGCNTAYCCNAARCCN------GGN TAYCCNCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GCNATHCAYGARGARAARTCNAGYGCNGARATHAARYTNMGNGGN AAYYTNGARMGNYTNGAYCARYTNGARTTYGARAARACNATGATHTCNGARCAYGCNTCN GARYTNCARGGNACNATHCAYGAYYTNGTNTCNCARAARGARATGACNGARAARGARYTN AARGARGARATHMGNGCNMGNATHTCNGCNGARGARMGNYTNAARGARGCNGARMGNTCN YTNAAYTCNYTNGAYCAYGCNGTNCARGCNCARTCNCAYMGNATHGARCARGARGCNAAR AAYGARATGAAYGTNAGYGTNMGNAARYTNAARCAYTTYTTYGARGAYYTNGTNGARGAR GCNAARATHTCNTCNGAYCARCCNATHGTNATHMGNAAYGGNYTNATGGCNMGNAARACN YTNGCNMGNMGNGCNAARACNGTNMGNTAYGARAAYMGNMGNMGNTCNTCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYGAYGARATHTGYGAR TGYTGYGAYAARATHTTYAGYYTNMGNTGYTGYAAYGTNTGYACNAAYAAYAGYYTNCAY AARYTNYTNMGNYTNGTNGAYGTNTGGTCNATHAAYACNGTNTTYATHGTNYTNTGYATH GGNACNATHGGNGTNGARGAYATGTTYCCNGTNTTYGCNTCNACNACNAARGAYAGYGGN GGNYTNGGNTTYTCNACNAGYGARATHGGNACNTCNYTNGGNATHATHACNATHCCNYTN YTNTTYATHCARATHAARATHTAYCCNYTNYTNGTNGCNAARYTNMGNATHMGNAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNTCNMGNGAYGGNYTNATHTGY ATHAARMGNGAYAAYTGYTAYCAYCCNGTNTGYAGYGTNGGNAARTTYAAYGTNAARTCN GGNTTYTGYCCNYTNTCNGAYAARTAYAGYYTNCARCCNTAYYTNTTYGARAAYCCNGAR GAYMGNMGNCAYTAYMGNAARCAYYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TTYGARTTYGAYGARTCNGAYGAYMGNCCNAAYACNAAYYTNTCNTCNTCNACNYTNACN GGNGAYAGYAAYTCNMGNMGNCAYGAYTCNTCNTTYACNGGNTAYGARGGNCCNAAYATH TCNYTNYTNAARYTNCARAARAGYACNTGGCAYGCNGARATHGARCCNCCNATHTAYGAY TAYGARMGNYTNAARATHACNAAYTTYGAYYTNCCNAARGAYGTNGAYACNAAYCAYYTN GARATHCAYYTNACNAAYGARGAYTTYGARGARYTNYTNAARATGCCNMGNGARMGNTTY TAYMGNATGGCNGARTGGAARMGNAAYGAYGTNAARMGNAARYTNAAYYTNTAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GGNTTYGTNCARTGG AARCCNGTNTCNTAYTTYGGNAARGARMGNGGNMGNAARACNGTNACNAARGTNAARAAY TAYGAYYTNAARAARYTNGAYGAYATGTCNTCNYTNAAYGCNACNYTNYTNGCNGCNYTN TTYGGNAARGAYYTNTTYGAYGGNAARTCNGAYATHAARAARATG---AAYATHTCNTTY GGNCARAARGARGAYGGNTTYTAYYTNGARAAYAAYTAYACNGTNTGGAAYGCNGCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GARTTYGTNYTNGCNATHTTYGCNTTYGCN ACNACNACNAGYCCNGAYACNTCNACNACNTTYACNGTNMGNGAYTGYGGNAARACNAGY GGNGGNAAYGTNACNGGNTCNGCNTCNAARACNTAYTCNTAYAGYTAYCCNTAYGAYYTN GARAGYGTNTGYTTYAARYTNCCNGTNTGYGARAAYAAR---CAYCAR---------TCN ACNTTYTGYYTNYTNGARGGNTCNCARTCNGCNGCNCARTTYTAYGTNTTYGTNGGNGTN ATHGTNTTYYTNTAYTGYYTNGGNGCNYTNGTNYTNTAYGTNTTYTTYGAYGARYTNTAY MGNMGNAAYACNMGNATHGTNYTNGCNGAYTTYATHATHTCNTGYGTNYTNACNYTNTTY TGGATHATHAGYTCNTCNGCNTGGGCNGCNGGNYTNGAYGAYGTNAARYTNTAYACNGAY CCNTAYGAYGGNGGNATHTTYAAYGAYAARATHGTNGARTGYAARGARAARGGNGCN--- TGYTTYACNTCNGAYGARGGNAAYTTYGCNAGYYTNAAYGTNTCNATHATHTTYGGNTTY YTNAAYTTYGTNGTNTGGATHGGNAAYYTNTGGTTYYTNTAYAARGARACNCCNTGGTTY AARGTNCARGCNAARCCNCCNACNCARCCNYTNTCNAARGCNCARYTNGAYTGYGARTGG MGNYTNGCNTCNTGYYTNMGNACNAARATHGARCAYATHMGNCARAARYTNAARGARAGY GARAAYYTNTCNTCNTTYTTYAARACNTTYATHGARATHGCNGARAAYTGYYTNAAR--- CAYGGNATHCCNGGNAARCCNTGGACNGAYCAYAAYCARAAYATHYTNAAYCARYTNCAR AARATHGGNTGGAAYAARGTNATHGAYYTNTCNGARAAYTTYTCNAGYGTNGARATHGGN TGYTAYGAYMGNGGNCAYMGNCAYCAYAARYTNMGNGTNAAYTTYGAYAARGARAAYTCN CARGCNMGNCCNAAYTGYGTNACNGAYYTNCCNCARCARTTYGARTTYCAYTGGTCNACN ACNGCNCARYTNAAYGAYYTNATHYTNCARTTYGARGGNTGYYTNGGNAAYTAYCARGAR TTYTGGAAYATGGTNGARGARATHGAYMGNAGYACNTGGGTNYTNGARCCNGARMGNCCN ACNTAYTCNTGYACNTAYMGNMGNGTNGCNYTNGGNCARAAYYTNTCNYTNCAYATHATH ATHAAYCCNYTNCARCCNTCNAGYYTNCCNGARTGYMGNATHYTNGGNTCNGARTCNGCN GTNGCNCCNYTNMGNGARAARYTNAAYATHAAYYTNCAYAAYTGGGAYYTNGAYMGNTCN YTNYTNAAYAAYYTNCARGARGTNYTNGARATHGAYTTYCCNACNCCNTCNGAYACNAAR AARGARGARYTNAGYGTNGAYTGYGGNATHTGYTAYAGYCAYCARYTNGGNGARGARATH CCNGAYATHGTNTGYCARTAYCCNCARTGYAGYCARTCNTTYCAYTAYACNTGYYTNTAY GARTGGTTYMGNAGYTCNTCNTGYMGNCARAGYTTYAAYTAYGTNTTYGGNGARTGYCCN TTYTGYAGYAARCCNATHMGNGTNAARATHCARGCNTTYCCNCCNCCNCCNCCNCCNCCN CCNCCNCCNCCNGARAGYTCNACNCCNAARATGGGNGAYGARAAYAGYATGGAYATHGCN TCNGAYGGNGARGAYGAYCARGCNACNAGYCCNCARYTNGGNAGYGCNTCNGCNATGTGG CARCARCARCARCARCARCARCARCCNTGGTGGCCNGGNGGNACNGGNCARATGTGGATG CARCAYCARGARGGNGAYGTNTCNGARGGNTTYGGNAAYAAYACNAGYGGNGGNCCNTCN GCNTTYGCNTCNCARGAYGTNGCNCCNMGNAARGGNGARTCNTTYAAYCCNTAYTGGGAR GAYCCNGARCARGAYGGNGAYGGNMGNMGNMGNCARCCNYTNYTNGGNGCNGARCCNCCN CAYCAYTCNAGYCAYCAYCAYCAYCAYCAYCCNCAYCAYAAYMGNCAYCAYCAYCAYCAY GAYMGNCCNGGNAAYGAYTTYGCNCCNGGNYTNGARGGNYTNCCNCCNATGGAYTCNTCN GGNYTNGAYGCNGCNAARMGNMGNGCNYTNCCNYTNTGGYTNMGNGARGGNYTNGARAAR ATGGARMGNGARAARCARAARCARYTNGARAARGARCARYTNAARCARAARCARGARGCN TTY------AARCARAARGARGARGARGARGARGARGAYGAYGAYGGNCARCCN------ ------------AARGTNCCNMGNAARAGYMGNTTYGAYTCNGAYGAYGARGAY------ ---GAYGAYGARAARGAYGAYGGNGAYGAYGARAGYAAYAAYGAYGAYGAYCARGTNCCN AARTCN---------------AGYCAYCARGAYGARACNTCNAARTCNTCNCCNGGNAAR MGNAGYCCNTCNCCNTCNGARTAYATGACNGARGARGARMGNGARTTYACNYTNATGGTN AARGTNAARMGNYTNYTNACNGARACNYTNYTNGARGTNACNGGNCARGARATGMGNAGY ATHGCNACNGARGTNTAYCARMGNGARAARAARAARGTNCARAARGCNCCNGCNAARCAR YTNGCNAARTCNTCNGCNYTNGCNTCNYTNTCNAGYYTNGGNYTNGGNTAYGGNTCNGCN AGYGAYAGYGARAGYGAYCAR------------CARGARGAYGAYTCNGAYACNGAYYTN GARGAYMGNATHAARAARMGNAARGCNGARTTYGCNAARAGYCARMGNATHTTYAGYGAY GARGGNGAYGAYGGNGTNAARACNAGYTCNGCNGTNAARACNGAYMGNGAYATHAARAGY AARGAYTGG------------------AARGARGAYGCNAAYTCNGGNAARCAYAAYMGN GARAAYAGYGAYMGNAARTCN------------ATHGARMGNMGNGAYTCNGAYMGNAGY ATHAARGGNGAYAARMGNGAY------AGYAARGARAAYGTNAAYAGYMGNTGGGAYTCN AARGTNAARGCNGARATHAARACNGARATGGAYAARAARGARGARCAYAGYGARMGNGGN GGNMGNCAYGTNAARACNTCNGGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTAYAAYGGNATHGGNYTNCARACN CCNMGNGGNAGYGGNACNAAYGGNTAYGTNCARMGNAAYYTNGCNTTYGTNAARTCNMGN AARGARAARGTNGAYTAYAARGAYGARGAYGARYTNAARAARYTNGARATGTCNATGAAY AARCARCCNAAYCARGARATHYTNGAYCAYGARMGNAARMGNAARGTNGARYTNAARTGY ATGGARATGCARGARYTNATGGARGARCARGGNTAYACNAAYAARGARGTNATGGARAAR GTNAAYATGTTYMGNAARATGYTNATGGCNAARGARGGNGTNTCNGAY---ACNCCNATH GARAARGAYGARCAYGGNMGNCCNATHGCNAARGARACNCAYCARYTNGCNGARGCNAAY AARATHAARAAYGAYAARYTNAARGARGCNTTYGGNYTNTCNGAYTAYGTNGARGGNAGY GCNTTYGAYCCNGAYMGNAARGCNAARGARGARCARGCNAARGCNYTNGCNYTNGCNCAR AARAARTAYAGYATHGTNAAYAGYTCNGARGARGARAAR---------GARAGYTCNCCN GTNCCNAARAARAARAARAARAARNNNMGNCAYGARGAYGGNTCNTCNCCNGARMGNAGY AARGARAARMGNAARAARAGYMGNAARCAYAGYAARMGNGAYMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARGAYYTN AAYAARTCNMGNGCNAAYTAYGCNGARYTNGARTCNACNATHGGNAARYTNAARGCNAGY YTNCAYACNAAYACNTCNAAYCARAAYAARGAYMGNACNMGNATHCARGARYTNTCNGAR GARATHATGAARYTNGTNAARMGNCAYAARYTNTAYCARMGNYTNYTNTCNGGNCAYATH GTNATHCCNACNAARGAYMGNGGNTTYAAYCARTTYTCNTGGYTNGAYYTNACNGARGTN GTNTTYGARCARGTNACNGCNYTNATHGAYATGGTNCAYACNTCNGAYAARAARATGAAR CAYAAYTAYATHTCNTCNAARAAYCARGARGARGCNTTYTCNTCNYTNAARCARGARCAY GARCARCARATHAGYAARYTNACNAAYATGGCNMGNGARMGNGARTCNGCNTGGCARMGN CARAARGARGARYTNGARCARCAYTAYAAYGARATGYTNTCNGAYGTNCARTCNCARTCN AARAARAAYCARGCNATHGCNGAYCARGCNTGGGARAARGTNMGNGCNACNGGNAGYGTN CARCAYGGNYTNGARACNGARGTNGTNGARYTNMGNMGNGARYTNGCNGARTCNCARGTN CARGCNTCNTCNYTNYTNTCNGTNTGYGCNYTNYTNAGYGGNGCNYTNTAYCCNYTNTAY ACNAARGCNGCNATGYTNTCNTCNCARMGNCAYATHYTNGARGAYYTNTTYTGYAAYTGG GARAGYTGYMGNGAYMGNGCNATGTAYYTNTGYTCNGTNYTNAGYTCNGGNMGNGARAGY GAYCARGAYCARCCNGARMGNGAYAAYAARTTYCARMGNMGNMGNAGYCCNATHYTNMGN TTYMGNATGGGNGTNATHGCNGTNYTNGCNGCNAAYMGNYTNGCNTAYYTNGGNTCNGGN TGYAARAARTGYTTYGTNACNTAYAAYTCNTCNGTNAAYCARAAYGGNYTNGCNGTNTCN ACNGGNGAYGAYGGNMGNYTNACNGCNGTNAAYATGAGYGTNTGYAGYGARAGYGARCCN GTNACNGGNTTYGGNCCNTTYTCNAARGCNGARAARAARYTNGGNACNTGGYTNACNAGY TCNGARYTNYTNGARACNGTNATGGCNTCNATGACNGARYTNCARGARTCNYTNMGNATH AAYAARAAYCARAAYAAYCCNACNGARGTNAARYTNGTNYTNAAYGCNGCNMGNACNTCN TTYACNAARTAYATHGAYMGNYTNGCNYTNTTYTTYCCNGCNTCNTCNYTNCCNGTNCAY TCNTCNATGMGNGARMGNTCNTCNYTNYTNMGNAARYTNGARMGNCCNYTNTCNCAYCAY YTNMGNAAYATHTCNTTYAAYTCNAARGGNAGYYTNATHTCNTCNCARGARGTNATGAGY AAYYTNCARAAYCAYATHYTNGAYYTNACNCARMGNYTNCAYTCNGCNGARAARGARMGN MGNCAYYTNYTNGCNGAYYTNAAYGARYTNAARCARCARATHGGNGAYGARAAYACNTCN YTNCARAAYTCNACNGAYAARCARTCNGCNGCNAARGGNACNAARTAYGTNGCNATGGAY AARTTYGARAARGTNTGYGTNGARYTNTCNGGNGCNYTNMGNMGNGARCARAARGCNCAR GTNYTNYTNCARGARCARAGYAAYCARYTNGCNGARYTNACNTCNMGNYTNGAYATGTGY GCNTCNGAYGGNGTNCAYAARGARAARAGYYTNGTNCAYATHCARGARGGNYTNACNGAR ATGCARGGNCAYYTNMGNCAYAARGAYCARAAYYTNMGNCARATHGGNAARCARYTNGCN CAYGTNGARTAYGARMGNGAYACNYTNCARAGYAAYYTNAARGAYGCNGARAAYGCNYTN MGNACNGCNGCNMGNGAYAARGARATHYTNGCNCARTAYATHAARAAYATHGGNAGYGCN YTNGAYACNTCNAARAARCARTTYYTNATHATHAGYGARCCNTCNCCNYTNTCNAAYGAY GTNTCNYTNTCNMGNYTNYTNYTNGAYGCNGAYYTNATHCCNYTNGAYATHGGNAARACN GGNCCNGARYTNATHTCNYTNCARAAYYTNGTNGGNGGNTTYGTNGAYGCNCARCAYCAR GCNGTNAAYAARATHMGNTCNYTNGARGARGARATHGTNTCNCAYMGNAGYCAYATHGAR TCNYTNAARAARGARYTNAGYAAYGCNGTNCARMGNGARTTYAAYCARCARYTNGARTCN GCNACNGAYGGNGCNTAYTCNGTNYTNACNGAYCARGARGARGAYYTNGTNCARYTNAAR CCNGAYACNGAYAAYTCNTAYGARAGYYTNCCNACNCCNMGNAARYTNACNCCNCCNACN TCNACNAGYYTNGGNAAYCCNTCNYTNCARCAYAARAARTCNGCNTTYCAYTCNGTNAAR TCNAGYAGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNACNCARTAYATHGCNCCNYTNATGGCNAAY TTYGAYCCNTCNYTNAGYAGYACNTCNAAYATHTAYTAYYTNAGYGARGARGAYTCNTTY ACNGTNGARTGGMGNGAYGTNMGNYTNCARGAYCARYTNGAYTTYGGNAAYTTYACNTTY CARACNTCNYTNTAYAGYAAYGGNAGYATHAGYTTYGTNTAYAARGAYATHCCNACNGCN GTNAGYAARATHTCNGAYGARAAYCAYCCNGTNAARGTNGGNYTNTCNGAYGCNTAYTAY AAYGAYACNTAYATHAARAGYATHGGNATHMGNMGNMGNACNATHTAYGARTAYCAYCAR GTNGTNYTNAARAARAGYYTNGTNAARACNGGNGCNGTNATHTTYGTNAAYCCNYTNCCN ACNTGYAAYATGYTNGARGAYTGYGARTCNTGYACNAGYCAYACNAAYGTNAARTTYGAY TGYATGTGGTGYAAYACNATHGGNMGNTGYTCNGAYGGNYTNGAYTGGTAYMGNCARCAY TGGGAYAARTTYAGYTGYAAYAAYYTNAGYACN--------------------------- ------------------------------------------------------------ ---------------------------------AAYCARACN------------------ ------------------------------------------------------------ ---------------------------------ATGGAR--------------------- ------------------------------------------------------------ ------YTNGARACNGTNMGNYTNAAYTCNAARYTNTCNGARGARYTNGGNTCNGCNMGN AARGARATHGARTTYYTNAARGGNMGNYTNAARGARYTNGARATGAARCARYTNGCNMGN GARTGYACNCAYGARMGNTAYAAYMGNAAYAARMGNCCNAARTGYAAYGGNGTNYTNAAR TCNAGYTCNCAYMGNGTNTCNGCNCCNCCNGGNAGYYTNYTNTAYGCNGARCCNYTNTAY GGNTGYAARTGYACNGCNTGYGARGARGCNATGGGNAGYGAYATHCAYTCNGCNYTNAGY GCNGCNYTNAAYGARGARYTNCARAARTTYCCNATHAGYTCNAAYGTNYTNGTNCARYTN GGNGAYCAYGTNGTNACNAARGGNGARAARACNGGNMGNATHMGNTAYATHGGNCAYYTN GAYAARATHGGNCARCCNAAYATGGTNTTYGTNGGNYTNGARYTNGAYGCNCCNGTNGGN CAYCAYGAYGGNTTYTTYAAYAAYAARMGNTAYTTYTTYTGYCARMGNGAYCAYGGNATH TTYGTNCCNYTNCAYGAYATGGTNTGYAARGTNGGNGCNAARAGYGARAGYTGYTGYCCN TCNYTNTGGGGNAARCCNAARYTNTTYTTYYTNGCNTGYTGYYTNGGNCARGCNTAYCCN AARGCNATHCCNMGNCCNCCNCAYGARGCNACNCCNACNGTNCARACNCARAAYTTYGTN TGYGGNTAYCARGAYTTYTTYATHGGNTAYGCNACNGGNAARGGNAARGTNTCNTTYMGN GAYACNCARAAYGGNACNTGGTAYATHAARGARYTNACNGARATHYTNACNAARCAYCAY GARAARGTNAGYTTYCARCAYATGGTNGTNYTNGTNAAYCARGCNGTNGCNAARAAYAGY CAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHTCNGGNYTNGCNYTNTGYGGNGCNGARGTNCARGTNGCN TCNGTNGTNYTNMGNTGYCAYATHCARATGGARGAYGARGTNAAYMGNGTNATHMGNAAY YTNACNGAYTAYAAYTTYCCNGCNGARAARAGYTTYGGNYTNATGTAYGCNTGYGTNGGN MGNGGNCARCAYYTNTAYAAYAARCARAAYGTNGARGCNAAYATHTTYMGNAARTAYTTY CCNAARACNCCNYTNYTNGGNTTYTTYGGNAAYGGNGARATHGGNTGYACNTTYCCNCAR CCNGGNYTNATGCCN---------GTNACNAARACNCCNAARCCNGAYCCNAARGTNGTN AARGGNGARGAYGARYTNACNCCNGCNCARYTNAARMGNCAYYTNGCNGARATGMGNGAR AARYTNAAYGARTAYMGNAAYAGYCAYGTNCCNAARATHYTNCAYTCNTAYACNACNGTN ATHTGYYTNGTNGCNYTNCCN------------AARMGNGCNGARGTNTCNACNYTNYTN TCNCARGTNTTYAARAAYGARCCNATHCCNGAYTTYGARATGAAYGCNCARACNATHCAR YTNYTNCAYCARYTNTCNGCNACNAGYCARTAYAAYGARAARAAYGCNAARYTNTAYGTN GARGAYYTNAARAARAARGCNGARGARTAYAAYGCNGAYGGNCARCAYGTNGGNAAYATH YTNAGYAARYTNGCNYTNGGNCARAAYAAYTTYTCNGTNTCNGGNGCNGCNTGYYTNGAR GCNYTNGCNMGNACNGGNGCNGCNYTNAGYGTNAARGAYGCNTCNGAYACNTGYTAYATG YTNTCNYTNCARGARYTNCAYTCNAAYGTNAARGARYTNACNGARAARYTNCARTCNGCN AAYGARGAYATGCARAARYTNTCNTGGAARAARCARGAYATHYTNAARAARCAYAAYTCN YTNCARCARGCNYTNGARACNTTYGARMGNMGNTCNGCNCARGARACNACNCARATHGCN GARAARAARAAYAARACNATHTCNYTNAARGARACNGCNGARGARAAYGARATHAARATH GCNAARYTNAARATHGARYTNGCNAARACNGGNGTNAGYGARTCNGAYTTYCAYGAYAAR YTNGTNAARAARMGNGARAARYTNGAYAGYYTNGARAARGARYTNGCNCCNYTNAARTCN GARYTNCARTCNTTYGCNAGYYTNCCNCCNGAYGCNGTNGARGCNAARGTNAARATHGAR CARYTNAARMGNGARYTNATHCARYTNCARACNCARATGTCNGARTGYGTNGAYGTN--- ------------------------------------------------------------ ---------------------------------------TGYCCNAAYACNGGNAGYCAR GAYAGYTTYGAYATHAAYMGNTAYYTNGGNAARTGGTAYGARTAYGARMGNTTYTCNGCN YTNTTYGARTGGGGNGTNATHTGYGGNMGNGCNGTNTAYGGNYTNAAYGAYGAYGGNAGY YTNAGYGTNGARAAYGGNGGNTAYMGN------AARATHYTNGGNYTNAARGTN------ ---CCNACNTCNGTNACNGGNAARGCNACNATHCCNGAYCARTCNMGNCCNTCNGARYTN CAYGTNTCNTTYTCNAARTTYGAYMGNTCNTCNACNGAYAAYCCNAAYTAYTTYGTNGTN GAYACNAAYTAYACNAAYTAYACNGTNATHTTYTCNTGYACNAAYYTNCCN---YTNTCN TAYAGYATHCARTAYGCNTGGATHYTNACNMGNCARMGNGGNGTNGCNCCNGAYAAYYTN GCNGARYTNAARTCNAAYYTNCARTCNAARGGNGTNGAYYTNAGYGARTTYAARTCNATH GAYCARTCNGAYTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNGAYGAYGARGCNGGN AGYAARMGNMGNATHAGYACNATHAAYMGNTAYYTNAAYGARAARGGNTAYGAYGTNGAY MGNATGTGGGCNGAYATHGAYGAYGTNATHATHAARACNGTNATHTCNGCNCAYTCNGTN YTNAARCAYAAYTAYMGNTCNTGYTTYCCNAAYCAYATHMGNGGNTCNGCNTGYTTYGAR ATHYTNGGNATHGAYATHYTNYTNGAYAARAARYTNAARCCNAGYATHYTNGARGTNAAY CAYTCNCCNAGYTTYACNACNGAYGCNCARYTNGAYMGNGARATHAARGGNACNYTNATH TAYGAYACNYTNMGNYTNATHAAYTTYGGNGCNGTNGAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNATHMGNMGNGTNGTNGGNGGNCARCAR YTNGCNATGGGNGCNTGGCCNTGGYTNGTNTCNYTNAAYTAYAARGARCAYCAYGTNTAY YTNGARYTNCARGGNYTNGAYCAYYTNTGYGGNGGNTCNYTNATHCAYCCNYTNTGGATH YTNACNGCNGCNCAYTGYGTNCAYTAYATGTCNGGNAGYGAYGGNYTNGGNGTNCCNTCN AAYTGGGTNGCNGTNYTNGGNGARTAYAAYMGNMGNGTNGARGARMGNACNGARCARMGN YTNGARGTNGARGCNATHTAYATHAGYCCNAAYTAYACNYTNAAYCCNAARYTNACNGGN GAYATHGCNYTNYTNAARYTNAGYCARCCNGCNMGNGTNACNACNACNGTNAARCCNGTN GAYATHGAYACNAAYMGNGAYYTNCCNGAYGGNACNGARTGYACNGCNGCNGGNTGGGGN CARCAYACNGCNGAYGAYYTNGGNCARCCNCARTAYGGNAAYGGNACNATGGTNCCNCAY GTNATHAGYGTNAARAARGARTCNTAYGGNGAYTGYYTNTCNTCNTAYGGNMGNYTNTGG CCNMGNATHGAYGAYACNGTNYTNTGYTTYTAYTCNGAYGAYMGNAARGAYACNTGYAAR GGNGAYTCNGGNGGNCCNYTNATHTGYMGNAAYCCNTCNGGNAAYYTNGTNYTNACNGGN ATHGTNTCNGTNGGNATGGGNTGYGGNGARGARAAYTAYCCNGGNATHTAYACNMGNGTN TCNAGYTAYACNAGYTGGATHYTNCARACNGTNGAYGCNCAYACNGAYATGMGNMGNMGN YTNGAYGAYCCNCARYTNYTNACNGTNGAYACNGTNYTNAAYATGYTNATHTCNTTYMGN GARATHCARGAYTAYAARGCNATGATGAARYTNGTNGARGAYGTNAAYAARAGYACNAAY GTNAARATHGAYAARAAYCARGGNATHCARTAYATGTAYGCNTTYGCNYTNAAYMGNAAY GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GTNTGYAGYMGNCARAARTCNGTNMGNGTNATHATHCARGGNYTNGAY GCNGCNGGNAARACNACNYTNYTNTAYMGNYTNAARYTNGGNGARGTNGTNACNACNATH CCNACNATHGGNTTYAAYGTNGARACNATH---TCNCAYGGNGGNATGGARATHGTNGGN TGGGAYYTNGGNGGNMGNGAYAARATHMGNCCNYTNTAYMGNCAYTAYTAYGCNGGNAGY GARGGNTTYATHTAYATHATHGAYAGYGCNGAYGTNGAYMGNATHGAYGARGCNATHGAY GARYTNAAYACNATGATHYTNAARAAYGARGARGTNCARAAYTCNGTNGTNATGGTNGTN GCNAAYAARCARGAYYTNGARAAYAGYGTNGGNCCNGARAARATHGARAGYAARATHAAR GARACNTAYACNYTNGGNYTNGGNYTNTCNYTNTTYGTNATGCCNTGYAGYGTNACNACN GGNCAR------GGNYTNCARTTYGCNTTYGAYCAYTTYGTNAARYTNGTNAARGCNAAY CARAARGAR---------------------GAYAGYAAYGTNAARCCNAARGAYGAYGTN ACNTCNAARGARGARGARMGNGAYGCNTCNTCNGGNATGTTYYTNAARGAYCCNATHAGY YTNYTNAARTCNGTNYTNTTYTAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TTYTCNTTYMGNCCNGAYGCNACNMGNAAYGTNACNYTNYTNTGYGTN GCNGARAAYGCNATHTTYMGNGARGTNMGNYTNGTNYTNGTNAAYGCNCCNCCNGAYGAR GCNCCNGTNGTNCARGTNAAYGGNAARGTNATHAAYGARACNGTNGTNACNGTNAARATH GGNYTNCCNATHAAYYTNAAYTGYAARGTNGAYGGNGGNTTYCCNAGY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATHYTNTCNACNTCNACNAGYGCNYTNYTNCCNTCNGCNATHTCNGARGARYTNCAYCAY AARAAYMGNTTYATHGTNTCNCAYCCNACNAAYCCNCCNTAYTAYGCNCCNGCNACNGAR GTNGTNCCNTCNAARTGGACNGAYCARGARGTNGTNACNMGNACNGTNGARATHATGAAR GARGTNGGNCARGTNCCNATHYTNGTNAARAARGARGTNGAYGGNTTYGTNYTNAAYMGN YTNCARTAYGCNATHATGGGNGARGCNTAYAARYTNATHCARGAYGGNGTNGTNAGYCCN ACNGAYYTNGAYYTNATHATGTCNGARGGNYTNGGNYTNMGNTAYGCNTTYATGGGNCCN TGGGARACNGGNTAYYTNAAYGCNGARGGNATGATHAAYTAYGGNGAYMGNTAYAGYGAY ATGATHYTNGGNATHCARCARAGYTTYACNCCNCCNGTNMGNATGGARGGNGARACNYTN AARGTNATHCARGARGAYATGGARMGNYTNGCNGGNCCNGTNGARGAYATHCARYTNMGN MGNCARTGGMGNGAYAARMGNYTNGTNGCNYTNGCNAARYTNAARGCNGARATGAAYGCN AAYGAYGCNAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CAYATHCCNYTNAARTGYAAYGAR GTNGARAGYMGNGCNGGNACNAARATGMGNACNTAYATHGARAAYAARGTNGCNGARGCN GTNATGMGNAARTGYCAYAARTGYGGNAARMGNTTYYTNAARGAYTCNGGNTGYAAYAAR ATGACNTGYATHTGYGGNGCNACNAGYTGYTAYTTYTGYAARAARGARAAYATHGAYTAY AGYCAYTTYGAYAARAAYAARACNTGYGCNCARACNGAYCCNAAYGTNATHCAYCARMGN GAYATGAARGARGCNGCNAARGCNGCN--------------------------------- ---------------YTNACNTGGTGYMGNAAYGTNACNATGACNAARGTNYTNCARGAY AAYCARATGGAYCARCCNGARGAYGTNGTNTAYGAYGAYAARCCNAARMGNAARGTNGTN GAYGTNGARACNAGYATGMGNTAYYTNGAYAGYAARGCNTTYATHGARGGNTAYGGNGAY AARCCNGTNTGGTTYCAYTAYMGNMGNAAYTTYAARGGNAAYATHATGCCNCARACNMGN AARAARTGYGTNMGNAARGGNGARATHTCNACNTCNAGYCCNTGYCCNGTNTGYMGNGAY GARTAYYTNGTNYTNGAYGCNAARAAYACNAARYTNYTNGARCARTTYATHTCNCCNTAY ACNAAYGARATHTTYGAYTCNATGAARACNGGNYTNTGYCARGARCARCARMGNAARYTN ACNYTNGARGTNATGMGNGCNTGGGAYCARGGNTAYYTNGARATGACNGTNCCNTTYMGN ACNTTYGAYTAYGAYGAYTAYMGNAGY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------MGNAARYTNAGYMGNTCNAARTCNMGNCCNGGNGTNACNCARMGNAAYATH AARCARAARTTYMGNGCNYTNYTNAARAARTTYAARATHTCNGARGAYGCNYTNGTNGAY TCNGARGCNGAYCAYGAYCARATHCCNAAYCCNYTNGAYGARYTNTTYGAYGAYYTNGAY GAYTCNGAYTCNGGNCCNGARYTNGAYACNATGAGYGTNATGTCNACNCCNAARCCNAAR YTNMGNCCNTTYTTYGCNAAYMGN------------------------------------ ------------------------------------------------GAYGAYAAYCCN TTYTCNAAYYTNGTNACNGTNGAYTAYTCNTTYYTNGARGAYAGYGCNTCNMGNACNAAR TGYCCNAARTGYAAYAARTCNMGNAARTAYTAYTGYTAYAGYTGYTGYATHGCNYTNCCN CAYYTNCARGARAARATHCCNAARGTNAARYTNCCNYTNAARGTNGAYATHATHAARCAY CCNAARGARYTNGAYGGNAARAGYACNGCNCCNCAYGCNGCNATHYTNGCNCCNGAYGAY GTNACNATHTAYACNTAYCCNTGYATHCCNGAYTAYAAYCAYGARAARGTNATHYTNGTN TTYCCNGGNGARGAYTCNGTNAGYYTNGCNCARATHTCNACNGARAGYGAYGAYGCNCAY TCNAGYACNCARTCNAARGAYACNGAYGARGAYMGNCARGARTTYYTNTCNAAYAGYCCN TGYAGYTCNGAYAAYAAYYTNYTNAAYAARAGYACNTAYACNGCNTCNAAYACNAARATG TCNGAYAARYTNTGYGAY---------AAYYTNGCNYTNAAYGAYGCNATHATHTCNACN GARAAYACNATHCAYAAYYTNCARTCNGTNAAYGTNATHCARACNTCNCARACNACNCCN ATHGGNAAYYTNAARMGNAARMGNTCNYTNAGYAARGAYGAYGARGARGAYGARCARAAR AAYTCNGTNAARCARCARAARACNAAYYTN---CARAGYTGYCCNTTYGARAARGTNGTN TTYATHGAYTGYACNTGGAAYCARACNAARCARATHGTNAAYGAYGARMGNYTNAARGGN YTNAARAARATHGARYTNAARTCNGARYTNACNCAYTTYTGGMGNACNCARGARGGNATG CCNAARACNTAYYTNTCNACNATHGARGCNATHTAYTTYTTYTTYAARGAYTTYCAYACN ATHTTYYTNGAYCCNGTNTAYAARCAYGARTAYGAYAAYYTNYTNATGTTYTTYTGYTTY ATGTAYAAYAARATHAAR------------ATHYTNATHGTNGTNAAYMGNGAYATHCAR CAYTCNAARGTNATHAARAARCAYAARGAYYTNTCNACNAARGTNGGNATHCCNCARCAY TAYGGNATHTTYTAYGCNATGGGNTTYGCNATGTTYATGGARGGNGTNATGAGYGGNTCN TAYCAYGTNTGYCCNAAYTAYACNAAYTTYCARTTYGAYACNTCNTTYATGTAYATHATH GCNTGYYTNTGYATGYTNMGNATHTAYCARTAYMGNCAYATHGAYATHGGNGCNAARTCN CAYACNGCNTAYATHTCNATGGCNTTYGTNATHYTNATHGCNTTYATHGGNGTNGTNTTY AGYACNAAYATHTTYTGGATHTTYTAYGCNYTNATHCAYATGATGGTNACNYTNTTYYTN TCNGCNCARGTNTAYTTYYTNGGNMGNTGGAAYATHGGNTGGTCNTCNTTYAARMGNTTY ATHCARTTYYTNATHTTYGAYYTNMGNMGNTGYTCNMGNCCNGTNAGYCCNAAYMGNTTY ATHATGATGYTNATHGGNAAYATHATHAAYTGGACNTTYGCNYTNTAYGGNGCNATHACN CARCCNTCNGAYTTYGCNAGYTAYYTNYTNGCNATHTTYATHGGNAAYYTNYTNYTNTAY TGYATGTTYTAYGTNATHATGAARYTNYTNAGYGGNGARMGNATHAGYYTNYTNGTNATG GCNTGYATGGTNACNTGYTTYGTNYTNTGGGGNTGYTCNYTNTAYTTYTTYTTYCARCAY GTNACNTCNTGGCARAAYACNCCNTCNGGNTCNMGNGCNGGNAAYMGNGARTGYATHYTN TTYAAYTTYTAYGAYTCNCAYGAYGTNTGGCAYTTYYTNTCNGCNTTYAGYATHTTYTTY TCNTTYATGATHYTNYTNYTNYTNGAYGAYGAYATHTCNYTNAARCCNMGNAAYCARATH CCNGTNTTYGAYTCNMGNGCNGARGGNGCNGGNGCNGTNCCNGTNGTNGTNGARGTNGAR GAYGARCARAARACNGAYGGNMGNAGYAGYGTNGARGCNATHGARAAYGGNGARTAYMGN GGNGARGAYMGNACNGAYGTNTCNCCNCCNGARGGNACNGARGAYAGYMGNGGNCARGGN CARTGGAARTCNCCNGARCARCARTAYATHGCNTCNGCNGTNYTNGCNCAYAARACNGAR ------------CARGARGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------YTNAARGARGTNCARGARGARMGN GAYAARYTNYTN------GARGGNCARGARGAYATGAARATHAARGAYYTNCARGARMGN YTNGCNATGYTNGCNMGNGARAAYGARGARAARGARGTNMGNATHAAYAARYTNAAYGAR GARYTNMGNACNACNAAYCARAARYTNAARGAYACNGARCAYCARYTNGCNATGTGYCAR TCNMGNCARGCNCAYGCNTCNGARGCNCCNAARTCNAARACNTGYATHATHATGATGTCN GAYACNCARACNACNTAYATGACNTTYTAYACNACNYTNCARCCNTTYACNGCNGAYATH CARACNMGNYTNAARCCNGAYGCNCCNGTNGCNYTNGCNTCNAAYATHGGNGCNGTNTCN AAYATHATHACNCCNAGYGAYCAYTCNTTYACNCAYAAYGARGTNGARGAYGTNATHAAR AARGTNATGYTNACNYTNGAYGTNYTNAARAARGTNGARGARCAYMGNTAYATHCARGAY GAYGAYGCNAGYCARAARTGGTTYMGNGTNTGYAARATGMGNYTNGGNTTYTAYATGAGY ATHAAYAARATGGCNYTNGCNAAYYTNMGNYTN---AARACNACNGGNATHGAYGTNGTN TCNGCNGGNATHGGNGGNATHAAYAARGGNGTNTAYAAYMGNATGAAYTCNGGNGTNYTN ACNCARATHCARTCNYTNGCNTCNGTNYTNCARYTNTCNACNTTYAARAGYAAYYTNAGY TGYGAYAARATGTAYCCNGAYTCNAAYATGGAYTAYYTNMGNAAYAARCARGARAAYCAY AAYGGNACNAGYGGNACNGARACNTTYTCNGGNAAYATHCCNATHGAYCARYTNCARATH MGNCAYAGYMGNAGYAGYGGNCCNGGNGGNCARAAYGTNAAYAARGTNAAYAGYAARGTN GARATHMGNYTNCAYYTNGAYTCNGCNAAYTGGATHCCNGAYTGGATHAARCCNMGNYTN ATHGARCARGARCARAAYMGNATHACNAARAAYGGNTTYYTNGTNATHAARTCNGAYATG ACNMGNAARCARATGYTNAAYCARGCNGAYTGYYTNAAYAARYTNMGNAAYATGATHTAY CARGCNTCNGTNYTNCCNAARGARCCNACNGARGARGARATHAARAARMGNGARCARMGN ATGATGAARGCNAARGCNGARGTNYTNMGNGARAARAARMGNAARTCNYTNYTNAARAAR TCNMGN------------------------------------------------------ ------------YTNGCNTCNGCNTCNGAYGAYGGNGTNGTNTCNTTYTGGGAYACNAAY ACNMGNGGNMGNGTNCAYTCNTTYAAYCCNAGYCAYCARGCNCCNGCNACNGAYYTNGCN TTYTCNCCNGTNAAYGAYCARYTNATGGTNTCNGTNGGNYTNGAYAARMGNYTNGTNYTN TAYGAYGTNCARGGNAARAARTCNATHAARACNATHGTNGCNAAYTAYCCNYTNACNTCN YTNGAYATGCARGAYGGNAGYACNGTNCAYCAYAARGTNATHTGYCCNTCNAAYACNGAR TCNACNGCNGCNATGYTNTAYGAYGTNMGNMGNTCNTTYAGYGAYGTNATGGCNGCNGAY GGNTCNTCNTGGCARGGNTGGTGGAAYACNAARTTYAGYCCNATHYTNYTNTCNMGNATG ACNGCNATHGTNYTNTGYAARGCNAAYYTNYTNGCNAAYYTNMGNTCNMGNGARAGYTAY ACNGAYGCNCAYTGGYTNATGTGYGARTCNGTNYTNGARAARTAYTCNTCNTGYGAYAAR YTNATHACNGCNGAYGAYGTNCCNAARATGCARGARYTNYTNAAYAGYATHTTYAARMGN TCNAARTTYYTNMGNTAYGAYATGACNAARTCNATHTTYMGNAARMGNTAYTCNCARGCN GCNACNAAYGTNATHCARTTYCAYGAYACNACNCAYCCNATGAAYGAYTTYGCNGARTTY CAYGGNYTNTTYCCNYTNGCNTCNTGYYTNAAYCAYTCNTGYTTYCCNAAYGCNGTNGTN GARAGYTCNGARGTNGARGCNYTNCCNGGNATHGCNGTNAARGCNGTNMGNGAYATHMGN GTNGGNGAYGARATHGTNYTNTCNTAYGTNGARCCNYTNGTNGARMGNCAYGARMGNMGN AARYTNYTNTGGMGNGARTAYAARTTYGTNTGYGARTGYCCNMGNTGYYTNCAYGARGGN ATHGGNCCNTAYGTNTGYACNAAYTGYGGNAARAGYTCNAARATH--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGGARGTNGAYGARGAYACNCAYGTNCCNGCNTAYYTNAARGTN YTNATGGARGAYTCNGAYACNTCNGARTGGYTNTCNTCNATHATHGAYYTNAARAAYGCN GTNATHGGNAGYAAYMGNGARAARTCNMGNGCNGTNMGNCARGGNYTNGTNCCNMGNYTN YTNAGYTGGATHGAYGAYGGNYTNTGYCCNYTNGAYYTNAARACNGARGCNGCNATHGTN YTNGGNAGYYTNGCNAARGGNGGNGARAGYACNGTNGTNAARYTNGTNGARGCNAARGCN GTNCCNATHYTNYTNAARTCNATGAAYACNTCNAAYYTNAARTAYAGYGARGCNGTNYTN MGNTGYYTNMGNTCNATHTTYATGCARAAYACNGAYGGNATHAAYTAYYTNTAYGARGAR AAYAAYTTYGGNAGYTCNTAYATHCCNACNYTNYTNGCNATGACNCARCARTCNCCNGTN TGYCARGARTGYGTNACNAAYATHYTNGTNTGYAGYTGYAARAAYAARGAYCAYCARACN TGYYTNYTNACNAGYCARGCNYTNCCNATHYTNTCNCCNYTNYTNCARTCNAAY---CAR TAYAARATHCARATGCCNACNYTNTGYTTYTTYGCNMGNATGTGYTAYAARAAYCAYGAR GTNTGYTCNGTNATHGCNAARGAYAAYAARYTNATHAAYACNTTYGTNAGYYTNATGAGY MGNGAYAARTCNACNGARATGCARATGGCNGCNGCNGARATGYTNACNAAYYTNCAYMGN TGYGGNGTNATHCCNTCNACNGAYTTYATHATHAGYMGNAARACNYTNGGNACNYTNGTN MGNATGTGYATGMGNGAYMGNAGYGTNGARGARAAYGTNAARGGNGCNGARATHYTNGCN TAYYTNGTNGARATHGARCCNGAYYTNCARGTNATGGCNAGYTAYACNTTYCAYYTNATH GGNGCNYTNGCNAAYTGYTTYMGNCAYCCNGAYYTNGAYAARATGTGYGCNAGYGGNAAR AARGAYGTNGAYTGGGCNAGYGARATGMGNMGNGCNGCNTTYYTNGCNTTYGCNTCNATH AGYGCNAAYGAYGARGARATHMGNGARAARGTNATHAARCARGARGGNATGATHGARCAY ATHCARACNTCNYTNTGYAGYAGYAAYGAYMGNGARGTNGCNGCNAGYYTNMGNTGYYTN CARTCNYTNACNMGNTCNGTNCARCARATHMGNACNGTNYTNCAYGAYAAYGCNGTNTGG AARCCNYTNYTNGARAARGTNMGNTCNGGN---------------AAYMGNGARATHATG GTNYTNGCNATGTCNTGYYTNTGYAAYYTNGTNYTNGARTTYTCNCCNAGYAARGARGCN YTNGTNAARAAYCAYGCNGTNGAYGTNYTNTGYGARYTNTGYMGNAGYCARGAYAAYATH GTNMGNYTNAAYGCNACNTGGGGNATHATGAGYATGTCNTAYTGYGCNTCNGARGAYYTN MGNGCNAAYATHATHAAYAARATGGGNACNGAYACNYTNGTNMGNMGNATHCARGAYCCN GTNYTNYTNATHMGNGARAARGCNYTNTGYATHGTNMGNAAYYTNYTNACNGGNAARATG ACNATHGAYAAYACNGTNAARCARYTNGGNAAYGARGTNATHGARGCNGTNTTYAARATH YTNTCNGAYCCNGARATGCCNTCNAAYGTNGTNACNCARGCNYTNTGYGCNYTNAGYAAY ATGGCNGAYGGNCCNTCNTGYAARGCNTAYATGATHGCNAARACNGAYGARATHAAYGCN GTNATHAARTAYYTNCARTAYCCNGAYAARGARYTNCARGTNCCNGCNATHCARTTYGTN AGYAAYYTNGTNGAYACNAGYGAYGAYGAYGTNGGNYTNTTYCCNGGNGCNGGNTCNTAY CARMGNATGYTNCARYTNAARACNYTNGGNGTNCARACNYTNYTNGARAGYYTNATHGGN ACNGGNATGGARGARGTNGARTTYMGNGCNCARCARGCNYTNAARTAYTTYGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TGYTAYAAYGAYGGNATHATHAAYYTNYTNGAR AARTAYTTYGAYATGAAYAARAARCARTGYAARGAYGCNYTNGAYYTNTAYAARMGNTTY YTNGTNMGNATGGAYAARGTNTCNGARTTYYTNAARGTNGCNGARAAYATGGGNATHGAY AARGGNGAYATHCCNGAYYTNGCNAARGCNCCNGCNAGYYTNYTNGAYGCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGNYTNGAR TGGATHMGNMGNGAYAARAARYTNTTYAARATHTCNTGGATGGAYAARMGNAARCARATH TGGGCNAAYGARGARAAYATHATHTTYAARGARTGGGARATGTAYAAYAAYMGNTAYMGN GARGGNGARTCNGARAAYTGGACNATGTGGAARCARACNTTYMGNAGYGCNYTNAAYAAR AGYCCNTCNGTNGAYGCNATHCCNGARYTNTAYYTNACNAAYAARYTNATGCCNTAYMGN GTNTAYMGNTTY---ATGGCNGGNMGNCCNAARTCNGGNATHACNGCNGAYACNGAYGTN AAYYTNGAYTTYYTNACNAARGARGARAARGARGCNYTNYTNTCNAARAARATGGAYATG ATHMGNCARMGNAAYAARATGYTNACNGARMGNCAYGARATGATHGARGCNGAYMGNMGN AARGCNGARGARTCNGGNAAYGCNGTNAARGCNYTNGAYAGYAARACNYTNCCNGCNGAR GGNGTNCCNAAY---AARCCNMGNGGNMGNGGNMGNGGNCARGGNCAR------GGNTCN CAYMGNGAYGGNAAYMGNTCNATHAARGAYMGNCCNAARTCNCAYGGNGAYACNYTNTCN TAYGARCCNATHGTNGAYGTNAGYGAYTTYACNGTNCAYMGNYTNGAYAAYMGNAAYAAR GGNAARGGNGGNCAR---CAYCAYCARGAYMGN------------------------GAY GTNCCNACNYTNACNCCNAARAAYMGNMGNAARCCNCAYCARAARGARGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNTAYAAYGCNGGNCAYGCNMGNTCNAAYMGNMGN--- ------------------------------------------------------------ ---------AGYGAYCCNAAYCCNCCNCCNGAYCCNTCNTTYAAYCCNYTNTCNGAYTGG MGNMGN---GGNGGNGCNGAYAARAARGARGTN------------CCNGARMGNTCNGAR CAYAARMGNCAYCCNMGNAAYTAYGGNGGNGCNGCNGAYYTNTCNAARGTNAARGAYTCN ATGAARACNATGMGNGARAARGARAARGARMGNCCNCARAGYTCNMGNCCNYTNGARATG GTNATGACNGGNMGNGARMGNAARAAYCAYGARCARTGGAARCARGARMGNGAYMGNTAY GAYAAYGARMGNATHCARMGNCARATGGGNGAYGGNGGNGGNTGGAARMGNGARTGGGAY TAYGAYAARATHGTNATGGARCAYGAYAAY------------CAYAGYMGNATGGARCCN GCNAARMGNCCN------------------------------------------------ ------------------------------GCNGGNMGNATHGGNAGYGGNMGNTTYGAY MGNGGNGAY---MGNGARGAYCAYCCNAARGCNGCNAAYMGNGAYGGNAARGGNGGNCAR CARCCNCCNCCNACNCCNCARCAYGCNCCNATHAGYCCNCARTCN---CCNACNCCNYTN ------CARCAYGGNGAYCARAARGCNCCNMGNGCNAARGGNMGNGGNMGNGGNMGNGGN MGNGGNMGNGGNGCNGGNCARGGNCARGGNAGYGGNCCNGGNGARMGNTCNCCNMGNCCN MGNACNTGGTCNGGNGGNGAYGAYMGNTTYGTNGARTGYCARAARGARATGYTNGTNGTN AARTTYGAYAAYACNGCNGGNGAYAAYTCNGTNGARGTNGARTAYGARGAYGGNGARCCN YTNTCNCCNACNCCNTCNTCNAARTCNTCNGGNTCNACNCCNGGNMGNGGNCCNACNGGN MGNACNCCNAAYCARGGNGGNGCNCCNMGNTCNAAYACNAARGGNGGNMGNCARTCNTCN AARCARGAYMGNAGYCCNCARAARGGNAARATHGGNAGYCARCARCARCARCARCARCAY CARCARTTYGTNGAYGCNGAYTGGGAY---------------AAYGGNCCNGTNAAYCAY TCNTAYGAYGGNTCNAARGTNMGNACNTCNTCNCAYTCNCARAGYCARGGNGAYAGYGAR GARTGGGARGAYTGYACNGARTCNTCNGGNGCNCCNGARGARGAYGGNYTNTCN------ ------CAYCAYCARAAYYTNCAYYTNGARTGYCARYTNAAYCCNGARGCNCCNGARTTY YTNCCNACNTCNCCNGAYTTYYTNAARACNCCNCCNGGNCAYGTNAARGTNYTNAAYTGG GCNGCNGGNAGYAAYAGYCCNACNTCNCCN------------------------------ ---------------CARTCNAAYYTNAGYCARCCNGTNYTNTCNCCNYTNTCNCCNMGN AARGGNTCNGAYCAYTCNTCNTTYTCNTCNCCNGGNTCNTCNGCNTCNACNMGNGCNMGN AAYMGNMGNGARGARATGGAYGCNATGCCNGARCCNGAYGARCCNYTNCCNCCNCCNTTY YTNYTNGARGCNGARATGTCNMGNGCNATGAGYCAYGGNGARAAYGCNATGAARGARGGN GARCARAGYGTNAARAAYGTNGARGAYGAYAAYGAYGAYGAYGAYGARAAYGARMGNTTY GARGAYACNGTNGAYGAYGTNCARGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGACNCARGAYGGNACNATHGTNGTNGCNGTNTCNAARGAYGTN YTNACNTCNYTNAGYCCNACNTGYCARAARTTYGTNMGNACNGTNTGYYTNGTNYTNAAR AARAARGAYYTNMGNATGATHACNGAYCCNGARATHGGNTGGGCNATHYTNACNTGYAAY ACNGAYGAYTTYTGYAAYCCNAARTCNGGNATH--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHGAYGCNAAYGGNCCNMGNCCNGARCCNGTNTAYYTNMGNMGNGAR AARCARACNCCNCCNACNYTNACNGCNTCNAARCAYCCNCAYGGNACNACNCCNGCNAAY AGYAGYCAYCCNCAYACNGGNCARCCNMGNCCNYTNYTNTTYGGNAAYGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CARATGTAYGGNTGYMGNGTNATHCAR AARGCNYTNGARTCNATHCCNTCNGAYATGCARGTNGARATHGTNAARGARYTNGAYGGN CAYGTNYTNAARTGYGTNAARGAYCARAAYGGNAAYCAYGTNGTNCARAARTGYATHGAR TGYGTNGAYCCNGARTAYYTNCARTTYATHATHGAYGCNTTYAARGGNCARGTNTAYAAY YTNTCNACNCAYCCNTAYGGNTGYMGNGTNATHCARMGNATHYTNGARCAYTGYACNGTN GARCARACNCARCCNGTNYTNGAYGARYTNCAYGARAAYACNGARMGNYTNGTNATGGAY CARTAYGGNAAYTAYGTNATHCARCAYGTNYTNGARCAYGGNMGNATGGARATGAGYGCN CCNGTNAGYACNATGMGNGCNGGNACNAAYAARYTNCCNGGNCCNAARGAYAARATGGCN AARGGNGAYAARAAYACNGCNTCNCARCARACNACNGCNGTNAARACNGARGGNCAYTCN ---AARGTNCARCCNACNCARGARCARYTNMGNYTNGCNCARATGATGAGYACNAAYCAR TGYGAYGCNGAYCCNAAYACNGTNAARCARYTNATGGAYATGACNGGNAARAGYGARGAY GTNGTNGTNATHGCNYTNCAYGAYGCNGGNAAYGAYGTNGARMGNGCNGTNATGATGYTN YTNGARGGNGGNGARGARCARGGNGARTGGYTNGARCARAGYGGNAARAARAARAARAAR ---AAYACNCARAARGARAAYGCNAAY------GGNGARGAYCARTCNGAYGGNMGNAGY AARGAYMGNGGN------------ACNGARAARGGNGGNGAYAAYCARGAYYTNCCNCCN MGNMGNGGNMGNMGNAAYGGNGGNCCNCCNCCNMGNYTNGCNMGNGGNMGNGGNMGNGAY AARGGNAAYTTYGGNGAYMGNGARAARGARMGNAAY---AAYGTNGCNGARGAYTGGGAY AAYGAYAARGARGAY------------------AARGGNCCNMGNAAYGAYMGNGCNGAY MGNGGNMGNTCNMGNGGNMGNGGNGGNTTYGGNGGNMGNAARCCNGCNGGN--------- GGNACNAGYAGYGGNMGNTTYAAYAAYAGYAGYGAYMGNGARAAYMGNGGNTTYACNMGN CCNMGNMGNTTYGARAARATGAAYAAYTCNCARTCNYTNGAYGGN------CCNGARATH GAYACNTGGACNAAYGARACNGCNGARACNAARGTNACNAAYAARGAYACNGAYTGGAAY AGYTGGAAYGAYTCNTGGGTNAAYGARGARGAYCARTGGACNGGNACNYTNGARGARACN AARGTNTTYACNCCNTCNCAYGTNAARATGCCNGARGCNGAYCCNGTNAAYAAYGARCCN CCNAGYTCNYTNGGNCARMGNYTNGAYGTNGGNAGYYTNTTYGARAAYGCNAARTTYACN AARGCNCCNGAYTAYAGYAARCCNAGYGGNGAYTCNTAYATHACNCARTTYAAYCARGCN GCNACNGARTCNATHAARAAYACNATHGGNATHGGNAGYACNACNMGN---CCNCAR--- ---------YTNCCNYTNTCNCCNCARAAYTCNACNAGYTCNYTNGGNYTNTCNAAYYTN GGNCARAAYACNGGNCARGTNCARGGNAGYTCNGTNYTNTCNTCNYTN---CARCARACN GGNCCNCAR---AAYTCNATGCCNCAYGCNATGGCNCARYTNTCNCARATHTCNCARCCN GCNTCNCARTCNACNAGYATGTCNCARATGGGNATGGTNTCN------------------ ------------------------------------CCNTCNAGYCARGCNAGYAAYAAY CARGCN---CCNCARCARTCNMGNATHCCNTCNGTNATG------------CARCARCAR CARCARCARAAYYTNCCNCARACNAGYATG---AAYAGYATGCARCARMGNCCNAARCCN CARMGNTCNAARYTNCCNCCNCCNTCNAARATHCCNTCNACNGCNGTNGARATGCCNGGN CAYATHCCNMGNAAYCCNCARYTNGAYGTNCARTTYGGNYTNGAYTTYGGNTCNGARTCN TCNGTNCARTTYGGNTTYGGNGGNAGYGGNGAYAGYACNACNGTNACNAGYTCNTAYTCN ACNACNTCNAAYGGN---ACNACNGTNATHTCNAAYCAYYTNAAYCARGGNCAYATGAGY CARTCNGCNGGNGAYGGNAAYTCNGTNTCNACNATHATGCCNTCNCCNTCNGCNGGNTCN ACNAARGTNCCNTCNGGNATHGARCCNCARGTNTCNAAYMGN---CARGGNGTNTTYCAY AAYTCNGTNTAYTCNTCNCCNCARCARAARAAYGARAGYCARACNYTNGARATHGARCAR AAYAARGTNAGYGAYTCNATHCCNTTYYTNTCNTCNCARYTNGARMGNAARTCNAGYCCN ---ATGTCNTCNCARMGNCCNGGNCARGCNAAYCARAAYYTNAGYTCNGGNCCNATGACN TCNAGYAARAAYGAYTCNACNAGY---GCNGTNGCNAAYAGYTAYTCNTCNGCNAAYGGN TAY---ACNTCNTCNTAYCARAGYCAYCCNAARGGNTCNTCNATHTCN------CAYACN GCNAAYTCNCARTCNTCNCARACNTCNTCNTTYCCNGGNCARTAYCCNGTNAAYCARTCN ---TAYCCNTCNGCNGGNCARGCNCARTTYCCNGCNCCNCCNAAYGCNACNCCNTTY--- CCNTCNGCNCARCCNTCNCARTTYAAYTCNTCNAAYTCN------TCNCARAAYCARTTY TCNTCNGGNCARAAYCARTAYTCNGTNGGNACNTCNACN---------YTNGCNCAYCAR AAYCARTTYCCNTCNAGYGGNCARAAYAAYTAYGGNACN---GGNCCNTCNCARTAYTCN GGNTAYCARAAYAAYAGYTCNTTYCCNTCNCAYCCNCARTCNCARACNAAYTAYCCNTCN AAYCARAAYGGNGGNACNGGNGCNGTNYTNTAYCCNGCNTCNACNCARTCNGGNGTNTCN TCNTAYACNTCNCARTCNAAYTCNTAYCARTCNCCNTCNGCNGGNTCNTAYCAYACNTCN MGNGAYGGNCCNACNAAYATHGCNGTNAGYACNCARTCNAGYACNGGNATGTCNTTYCCN AGYCARCCNCARAAYTCNAAYYTNAARCCNGCNGCNTCNCARAGYAAYTCNAGYTTYAAY TCNCARAGYTTYAAYGCNACNCCNACNCCNYTNCARCCNTCNTCNYTNGCNAAYAARYTN GGNGARAGYYTNTCNAARATHTCNATHAARGAYTCNTCNTCNGTNYTNGAYACNCAYCAR TCNTCNCARTAYGARCAYACNCARTCNGCNGCNAGYGTNCCNACNAGYGTNAGYYTNCCN TCNGCNTCNAGYTCNGCNTCNYTNTCNACNGGNACNAAYACNATHTCNTCNACNTCNACN GTNACNTCNGTNTCNTCNGCNTCNMGNGTNGCNTCNATGCCNTCNACNTCNGGNAARGCN CCNCCNAAYYTNCCNCCNGGNGTNCCNYTNATGGGNCARTAYATHATGGGNCARAGYACN ATHCCNCCNTTYTAYAGYGTNCARCCNCCNATGTAYGGNTAYGARGAYGTNCARYTNYTN CARCARMGNATGCCNATGCARACNGGNAGYTAYTAYGAYGTNAGYGCNTTYCCN---GCN CCNGCNGGNTCNAGYYTNCCNACNGGNMGNGAYCARCARCCNCCNATHCCNAGYGTNCCN TTYTCNGGNACNTCNGAYACNAARYTNACNMGNGTNGAYGCNCARAGYCCNAAYGCNTCN AGYCARCCNCARAGYGCNCAYTCNGCNGCNCARCARCCNYTNTTYAAYTTYCAYTAYGGN TAYTAYTAYCCNTCNATGTTY---GGNGCNGCNGGNYTNCARTAYCCNACNACNGTNTAY CCNATHCCNCCNGTNACNAAYGCNGCNGCNCAYCCNGGNACNACNTCNACNACNCARTTY CARAARTCNTAYCCNTCNCAYGTNTAYACNACNAARGGNTAYGAYGARGTNAAYCARGTN CARGAYTTYTCNAARACNGGNTAYGGNAGYTCNCARAGYTCNGGNAARGCNTCNGGN--- ---------ACNMGNTCNGGNACNAAYGARATHACNCCNAAYGCNTAYAGYAARTCNCAY GGNCAR---GGNTTYGAYAARCARGGNTAYCAYGGNGGNACNCCNCCNCCNTTYAAYYTN CCNYTNGTNTCNGCNACNCARACNGGNCCNATGGGNGCNCCNACNACNCCNTAYGGNGCN CCNTTYYTNCCNGTNATGGCNGCNCAYCARCCNCAYTCNCARATGATGCAYCAYCCNATH CARCARGAYTCNAAYAGYACNAGYTCNMGNGGNYTNAAYCCNGCNGGNGCNCARGGNAAR TCNGGNGCNGCNAARTCNTTYGGNGGN---CCNCCNTAYTGGAAYAAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGCNATHTTYGAY ATHYTNAAYCCNGCNATGYTNYTNAARYTNMGNYTNGTNGTNTAYGGNGTNYTNATHTTY TTYTCNTTYTTYATHTTYGTNGGNACNGCNGTNATGAARGAYAARGCNGAYAARGGNCAY TGYCCNYTNTAYATHACNAAYAAYGGNGGNTAYYTNGAYCCNGGNCCNCARTCNAAYTGY AAYTAYCCNATGGCNATHTCNATHATGTAYCARYTNYTNTAYYTNYTNTTYMGNATGGGN ACNYTNGTNYTNGTNYTNATGGGNAARTTYACNGCNGAYATGGTNYTNTTYACNGAYYTN GCNGARYTNGTNTAYGTNATHGTNGAYYTNTCNGCNTTYTTYYTNATHTTYATHGCNGCN TGYATHYTNTCNGCNGGNACNAAYAARACNTGYGAYGARYTNAARTGYGAYAAYTCNGAY TCN---------GTNTCNGCNTCNAARGCNGCNCARGCNGGNGCNTGGATHAGYACNTTY YTNTGGYTNTTYATHGGNATHTGYGGNTTYGTNGCNYTNTGGMGNGCNGGNAARATHCCN TTYYTNCCNGGNGGNGGNGCNGCNAARCCNGAYCCNGCNACNACNGGNTCNGAYCCNAAY CARCCNCCNATHGARACNCCNCCNAAYAAYCCNGAYGAYCCNCCNAARTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARATGGAYTTYAAR TTYAARAGYMGNATHCARMGNMGNYTNTAYCAY---------------------AGY--- AGYGARATGAAYAGYGTNAGYACNTCNTCNYTNCCNYTNACNGARACNTCNYTNGARTAY TTYCARGAYAGYTTYCCNGGNACNGARGGNYTNGGNMGNYTNGAYATGCCNATGGCNACN ACNGTNACNAARMGNAAYCARGTNTCNCCNTGYTCNATGGTNYTNTCNATGATGTAYGCN AARMGNYTNMGNCARMGNAGYAARCARTAYYTNGARTCNATGTCNTCNTCNGAYGTNTTY TTYATHTCNGTNATGATGGCNAGYAARTAYYTNTAYGAYGARGGNGTNGAYGARGARGTN TAYAAYGAYGARTGGGCNGCNAGYATHGGNCAYGAYGTNGARGAYGTNAAYCARYTNGAR ATGGAYTTYYTNAARGARATGGAYTGGCARYTNTTYGTNAARCCNGARGARTTYGAYTCN GCNYTNACNGCNGTNGARMGNMGNYTNGCNYTNAARGARGGNGTNAARMGNGGNTGGTTY AGYTAYACNGARATGGCNGTNYTNYTNGAYTGGGAYTCNGTNTAYAARYTNTGGAGYCAR GTNGGNYTNGAYTGYACNAARATGGTNTCNYTNTTYTCNGCNGTNTAYGTNGCNAGYYTN GTNAGYATGYTNGGNTCNGCNGCNATHGCNATHCARYTNTCNGGNCCNATGGCNTCNATH ACNGTNGCNYTNYTNTCNATHCAYCCNTCNCCNYTNCARGCNCCNTGYCAYCCN------ ---MGNTGYTGYCCNMGNTCNTGGAAYTAYCARTGYMGNAGYGCNAAYGTNMGNYTNCCN TGYTTYTCNCAYTAYTAYGGNGGNATHMGNGARACNTGYTGYCCNATHTGGCCNTCN--- ---GTNTAYATHAARMGNTGYYTNTGYAGYCARTGYGCNGTNYTNACNCCNACNTGYGCN CAYGARGGNMGNTGYCARMGNMGNTAYTCNAARAARAGYTTYYTNGCNGTNTGYTAYMGN AAYAAY---CARTGGGGNTTYYTNMGNTAYATHACNMGNTAYYTNCCNTCNAGYTGYTAY TGYMGNYTNAARMGNAARGAYTTYTAYGTNYTNTGGATHTGYGTNGGNGTNCAYACNTAY GGNTTYYTNYTNYTNAAYACNTAYTAYAARACNTTYGGNYTNYTNTAYATHGARGAYGAY CAYTTYYTNACNAGYATHGCNGTNGTNCARTGYYTNTTYACNCCNATHTGYACNTGGTTY GCNGGNTAYTCNGTNGAYMGNTTYGAYGTNAARTCNACNGTNATHGTNATHTTYAGYATG ACNTGYATHYTNGCNAGYTTYTTYTAYGTNACNTTYAAYAARTGGATGTAYATGTTYTCN TGYYTNYTNTTYGGNTGYAAYYTNGTNACNYTNTAYTGYYTNGTNGCNTCNTGYTGYAAR YTNTTYGGNCARACNTAYTTYACNACNATHYTNGGNYTNACNYTNACNTCNTCNTAYGTN YTNACNTTYACNGTNCCNCCNYTNGCNGGNTGGATHATHCAYACNTAYGGNTGGTTYGTN YTNTTYACNTCNGTNGGNGTNYTNTCNYTNATHTCNGTNATHATHYTNATGGTNTGYGTN CCNTGYTTYYTNATHCCNATHATHYTNTGGATHTTYCAYAARTTYGTNCARCCNTGGYTN TCNAARTTYTGGAGYAAYTCNGARAAYTAYGTNACNAGYAAYYTNACNTGYCCNATGCCN CARAARAARAAR------------------------------------------------ ---------------ATGTCNAAYGCNGGNTTYTTYMGNGGNACNACNGCNCARCARGAY ACNMGNTTYTCNGAYAARAARAARAARYTNATGAARACNATGAARTTYGGNGARAGYYTN GAYAARAARATHGAYATGACNAARGTNAAYGTNGAYAGYYTNAARCCNTGGATHGCNCAR MGNGTNACNGARYTNYTNGGNATGGARGAYGAYGTNGTNGTNGARTTYGTNTAYAAYCAR YTNGARGARMGNCAYCCNGAYGGNAARGARATGCARATHAAYYTNACNGGNTTYYTNAAY GGNAARAAYGCNMGNATHTTYGTNGCNGARYTNTGGACNCAYYTNTGYAGYGCNCARGAR AAYATHACNGGNATHCCNAAYGARTTYYTNGARCARAARAARAAYGARATHAARCARAAR CARGARGARMGNGARMGNYTNCARGARCARYTNAARAARAAYGARGARCARATHAARGAR AARYTNTCNMGNGARMGNMGNGARCARGARAARAARGAYYTNAAYAAYYTNTCNCCNGAY MGNCCNAARCCNGTN---------------------GARACNAAYGGNYTNAARCCNYTN ATGGAYGGNGGNGAYGGNATHGAYTCNAARACNGARGTNGCNGCNGARCCNAARCCNGAR ACNGARGCNTCNGGNGARCCNCARGCNGARACNGARGTNAARAARGAR------------ ------------------YTNAARGARAARGARAARGARMGNACNCCNGARMGNAARMGN GARAAYMGNGAYMGNGAYMGNMGNMGNCAYTCNMGNACNCCNGAYMGNCAYMGN---CCN MGNTCNMGNACNCCNGAYMGN---CAYMGNMGNGAYMGNGAYAARMGNCCNGCNTAYGAY MGNGGNMGNTAYTCNCCN------------------------------------------ ---CCNMGNMGNMGNTCNMGNTCNCCNMGNMGNMGNTCNCCNCCNCCNMGNMGNMGNTCN CCNCCNCCNMGNTCNCCNTCNCCNCCNCCNMGNAAR------MGNTCNCCNAARAARTCN GARGTNACNMGNMGN---------GCNMGNTCNAGYAGYGARAGYAGYTCNAGYGGNTCN GAY------------GAYGGNTCNGGNAARGARGGNTCNTCNCCNGARAARAGYGGNATH CARCARMGNMGNAAYTAYMGNAARCAYGAYGAYAGYGGN------AARTCNTCNTCNGAY TCNTCNGAYGARGAYGAYAARGARMGNAARMGNCCNCCNCCNCCNMGNGAYMGNMGNAAY GCNMGN------------AGYMGNMGNMGNMGNCCNTCNCCNTAYCCNMGNMGN------ ---CARAGYCCNCCNMGNMGNMGNTAYCCNTCNCCNMGN--------------------- ------MGNMGNYTNAGYCCNGTN---MGNMGNMGNAGYCCNTCNCCNMGNMGNMGNTCN CCNCCNMGNTAYTCNCCNCCNMGNMGNMGNAGYCCNCCNCCNTAYMGNMGNMGNATHTCN ATHTCNCCNMGNMGNMGNMGNCCNTCNCCNTCNCCNCCNMGNMGNCCNCCNTCNCCNTTY MGNMGNGGN---MGNMGNCAYGTNTCNMGNTCNCCNTCNAGYTCNCCNGTNAARMGNMGN MGNCCNTCNTCNCCNCCNTCNCCNCARATGAARTCNAARAARAARAARNNNTCNCCNCCN CCNTCNGARTCNGARGAYAGYTCNAGYTCNGARGAYTCNTCNCCNTCNCCN---CCNCCN CCNTCNAARMGNCCNCCNGTNAARGTNAARGAR---------CARCARCCNTCNAARMGN CCNATHCCNGCNACNMGNTCNCARAAR------------------------CCNTCNAGY GAYAGYTCNTCNTCNGGNTCNGARGAYAGYGAYGARGAYTCNGAYTCNGARAAYCCNGCN TCNCCNAARAARTGGMGNGARGCNACNCCNCCNMGNYTNGTNAARACNTCNCARCAR--- ------------MGNYTNAARCARACNCCNCCNTCNACNAARMGNAARCCNTCNCAYGGN ---------------------TCNMGNTCNMGNTCNCCNGTNAGYMGNMGNAAYAAYMGN TCNAGYCCNCCNGGNTCNGGNTCNMGNTCNCAYTCNMGNMGNCARAGYCCNCCN------ ------------CCNMGNAARMGNTCNTCNCCNACNMGNMGNTCNCCNTGGGARGARCCN CARMGNAARGAYACNGAYYTNTCNMGNMGNGAYMGNMGNCCNAGYCCNCCNMGNAARMGN CARGCNMGNTCNCCNTCNCCNMGNCARMGN------------AGYGARGGNGGNMGNGAY TAYMGNMGNMGNTCNCCNCCNTCNACNGARAARMGNAARGARGTNTCNGARMGNCARGAY CARAARCARCARGTNGTNMGNAARGARMGNCARCCNCCNTCNTCNGAYAGYAGYAGYGGN AGYAGYTCNGARGARGAYGGNAARAARGARMGNMGNACNATHTCNAARTCNATHTCN--- AARCCNTCNGGNGARAGYAGYMGNTCNGGNMGNMGNGCNTCN------CCNGCNAARMGN AARMGNTCNGCNACNCCNTCNCCNCCNMGNCCNCARTCN--------------------- ------------------------------------------------TCNAARTCNTCN AARMGNGAYGCNMGNGAYGAYGAYMGNCARATHGAYAARCCNAGY--------------- ---------TGYMGNTCNTTYAGYCCNGGNMGNGAYGCNACNCCNCCNMGNAAYGGNAAR GTNTCN------------------------------------------TCNYTNACNTCN GCNAARCCN------AARATHGAYAGYAARCCNGTNCARTCNGGNAGYAAYAGYGARTCN GARGGNTCNGAYTCNGAYAAYGCNACNAARAARAARAARAARAARAARGARAARAARCAY AARAARCAYAARAARCAYAARAARCAYAARCAYAARAARGARATHCCN---------GAR AARGGNGARGAYYTNGARCARMGNYTNMGNGARAARGCNYTNATGTCNYTNYTNCAYMGN AARAARTCNCARACNTCNCARGARCCNGAYAAYGAYTCNGAYTGYGGNAGYAGYAGYGGN GARGAR------------------------------------------------------ ---------------------------------------YTNGAYYTNMGNGGNGCNGCN TAYCCNYTNTTYGCNAAYMGNMGNACNMGNMGNGARACNTTYCAYTCNTGGGAYCCNAGY CAYACNCARAARCCNGAYGAYYTNGTNAAYYTNGGNTTYTTYTAYGCNGGNTAYTCNGAY TGYGCNMGNTGYTTYTAYTGYGGNYTNGGNYTNAARTAYTGGMGNCCNAAYGAYGAYGCN GCNTAYCARCAYGCNMGNTTYMGNCCNCARTGYYTNTAYAAYCARTTYGTNAARGGNCAR GARTTYGTNGAYCARGTNCARMGNAAYATHAGYGCNAAYGCNGARMGNAGYGAR------ ------GTNCCNAAYYTNGTNGARYTNATGAARTCNGAYGCNGCNMGNCARYTNATGGCN GARGGNTGGGAYMGNGAYGAYGTNMGNACNGGNGTNGCNAARYTNGTNCARGAYYTNGGN GARGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARATGTCNCAYCARYTNATHMGNATGGTNACN GAYTTYGAYTAYATGGARAARAARYTNCCNTTYTTYGAYYTNAGYCARYTNAARTAYAAR GARMGNGAYTTYYTNGARGGNATHYTNAARTTYTGGMGNAAYGARGAR------AARAAY CCNTTYGAYATHAGYAARTGYTGGGAYATGMGNYTNMGNCARYTNTTYGGNGTNMGNTAY GAYAGYMGNYTNAAYGCNTTYGAYTGGGAYTAYAAYATGGARGTNATHGARMGNGGNGGN TCNATHATHCAYYTNCARCARTAYAARTCNTGGMGNGGNGAYGGNATHGCNTAYACNATH MGNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CAYYTNGGN ATGTGGGAYTAYMGNGGNTTYAARTCNTAYTAYCARGGNTGYGARGAYCCNYTNTTYYTN TAYYTNCCNTTYCARGCNGTNCAYAGYTCNGCNAAYGGNCCNCAYYTNCARGCNCCNAAR GARTAYATHGAYAARTTYAARTAYATHGARAAYAARCARMGNMGNATHTAYGCNGCNATG GTNTCNGCNYTNGAYGAYGCNGTNGGNACNGTNTAYGAYACNYTNGARTCNACNGGNYTN YTNTCNAAYTCNATHATHGTNTTYACNACNGAYAAYGGNGGNCCNGCNAAYGGNTTYGAY TTYAAYGCNGCNAAYAAYTTYCCNYTNMGNGGNGTNAARGCNACNYTNTGGGARGGNGGN GTNMGNGGNGTNGGNTTYATHAAYAGYCCNYTNYTNAARCARMGNGGNTAYGTNGCNAAY CARATGYTNCAYGTNTGYGAYTGGYTNCCNACNYTNTAYAGYGCNGCNGGNGGNAAYGTN ACNGAYYTNAARAAYYTNGAYGGNTTYGAYTCNTGGAAYATGYTNAGYGARAAYGGNCCN GCNGTNMGNGAYGARATHYTNCAYAAYATHGAYCCNYTNGARAARAARGCNGCNATHMGN GTNGGNGARTAYAARYTNGTNGCNGGNCAYYTNAGYCAYAGYTGGGGNGGNTGGTAYCCN CCNTGGAARYTNCAYGGNGAYGARCAYGTNYTNCAYTAYYTNAAYTTYAARGAYGAYTTY GTNGARTCNGARGARAARAGYAARYTNMGNCAYGARYTNGAYTCNAAYTAYMGNAARTAY TGGCCNACNGAYGTNAAYGAYMGNYTNCARCARYTNAAYAARAGYMGNAGYAARGGNATH GAYGAYCAYCAYCCNAARMGNYTNTAYAARCAYATHCCNMGNGGNTCNCCNGTNAARATH GAYTGYGGNGTNAARCCNYTNAAYGCNAGYACNAAYTGYAARCCNACNCAYGCNCCNTGY YTNTAYAARATHACNCARGAYCCNTGYGARTAYTAYAAYATHGCNCARGARAAYCCNGAR ATHGTN---------------------------------------------GCNATHGAR MGNCCNMGNGGNGTNTCNYTNGARAARGCNTCNTTYTAYMGNYTNGAYACNGAYTTYCAR TGYYTNTCNAAYGGNAARGTNYTNCCNGCNGAYCAYGTNAAYGAYGAYTAYTGYGAYTGY GARGAYGGNTCNGAYGARCCNGGNACNTCNGCNTGYGCNAAYGGNYTNTTYTAYTGYGAR AAYAARCCNTAYAARGGNCAYTAYATHAARTCNTCNMGNGTNAAYGAYGGNATHTGYGAY TGYTGYGAYGGNTCNGAYGARTTYGAYGGNATHATHTCNTGYCCNAAYACNTGYGTNGAR AARTAYGARCARGARAARGCNGARCARGARGTNYTNMGNCAYCARCARTCNGARGGNTAY AARGTNAARCARGARTAYATGCARCARGGNAARMGNACNAARGAYGARAARGTNTCNMGN YTNAGYGARYTNGARMGNGARAARGARGTNYTNACNAARGARAARGAYGTNGCNGARGCN TAYAARAAYGARGCNGARGARCCNGARAARGTNGCNATHGAYGARCAYAARAARGCNTGG GARYTNGTNAARGARGARMGNCARAARGCNAARGAYGCNGTNGTNGCNGCNACNACNTTY TCNATHYTNGAYGCNAAYAARGAYGGNAGYGTNGAYTAYCCNGARYTNATGAARCAYAAR GARTTYGAYATHGAYTCNGAYGGNACNGTNAGYGARGARGARGCNAARGARTAYYTNGAR GAYAGYGARCARGTNGAYYTNGCNGTNTTYACNGARAARATHTGGCCNAAYATHAARGAR ATHTAYAARCCNGGNGGNTCNGARACNGARAARCCNGCNGGNGAYCAYGAYACNGCNACN CCNGGNGARATHGARGGNACNCCNGAYGTNGTNGARGGNGGNTCNCCN---GAYGAYCAY GARGARGARGAYGAYGARGAYGARGAYTCNGCNTAYGAYATHTCNGAYCARAARYTNGAY GCNGAYATHCCNGARGARGAYAARGARCCNGAYTAYAGYGAYGARACNAARMGNYTNATH GCNGCNGCNGAYTAYGCNMGNAAYMGNTAYGAYGARGCNGARACNAARGTNAARGAYYTN GARMGNGARATHAAYGAYATHAARAARTAYATGGARATHGAYTTYGGNCCNAAYGARGAR TTYGCNGCNYTNAARGAYCARTGYTTYGARTAYACNGAYMGNGARTAYACNTAYMGNYTN TGYCCNTTYGAYAARAGYACNCARAARAAYAARAAYGGNGGNATHGARACNTCNYTNGGN AAYTGGGGNAARTGGCAYGGNCCNGAYGAYGAYAARTTYGAYACNATGAARTAYGARAAY GGNCARGGNTGYTGGAAYGGNCCNAGYMGNTCNACNCAYGTNAAYYTNCAYTGYGGNTCN ACNAAYGCNYTNACNAGYGCNTCNGARCCNAGYMGNTGYGARTAYCARTTYGARTTYACN ACNCCNGCNMGNTGYGARTCNYTNAARCCNGTNGAYATHAAYGGNGTNCAYGAYGARYTN YTNGTNATHAARGARCARCCNMGNTCNTTYACNGTNAAYCARAAYGCNAAYACNTTYYTN ATGTGYAGYGTNTGGGGNAAYGTNGARGTNGAYTAYCARTGGATGMGNAAYGGNAARGAR ATHACNGAYTGYGAYAAYATHTCNGGNTCNAAYACNAAYGARYTNAARYTNTCNAAYATH CARGAR---------TCNGGNTGYTAYTGYTGYMGNATHTCNGGNGGNCARGARGTNYTN TTYACNCAYGAYGCNGTNYTNCARGTN---------------GAYAAYATHCCNTCNGAR GTNTAYACNGCNACNGAYAARGTNGCNYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TGGMGNTTYGARTTYTCNGTN ATHATGGCNACNATHYTNTCNATHTCNGCNTTYYTNACNATHGTNGGNAAYGCNATGGTN YTNACNGTNATHTAYMGNCAYMGNGGNATGMGNACNMGNACNAAYYTNTTYYTNGTNAAY YTNGCNATHGCNGAYTTYYTNGTNGGNGTNATGGTNGTNCCNTTYTCNATHACNACNYTN ATHGARGGNMGNTGGATGTTYGGNGARGARGTNTGYACNYTNAAYGGNTGGGTNAAYGGN GTNTGYYTNATHACNTCNATHCAYACNYTNACNTAYATHGGNATHAAYAARTAYTTYTCN ATHTGYMGNCCNYTNAGYAAYCCNATHCARYTNAARCAYATHATHATGATGATGTTYGCN GCNTGGYTNTGGGGNGCNATHTGYGCNTCNYTNACNACNGGNGGNYTNAAYTCNATHAGY TAYAARGTNGGNACNTCNCARTGYGGNCCNGARTAYCCNAARGARTCNAARGGNTAYATH TAYCAYACNYTNGTNCARGTNACNGTNATHGTNATHCCNTTYTGYATHYTNYTNTTYTGY TAYATHCARATGTTYTAYGARATHCARMGNCAYTCNGARMGNYTNMGNAAYAAYACNACN GTNGARGARGTNTAYYTNYTNAAYCARCARAARMGNATHGCNGTNACNYTNTTYATHGTN YTNGCNACNTTYATHATHATGTTYYTNCCNTAYAAYATGTAYTCNACNTAYACNACNGTN GARCARAARAARGARAAYATHTCNAAYTAYATHAAYCCNATHGCNTAYTGYTTYYTNTAY YTNAAYTCNATGTGYAAYCCNATHATHTAYGCNTTYMGNTCNCCNGCNTTYMGNGARGGN TAYAARGARATHYTNTGYCARACNCCNAAYTAYGTNATHMGNGAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GCNTGYCCNAAYCARYTNTCNTCNYTNGAYAARGAYGAYGAR GAYTAYCARMGNTAYMGNTAYTTYGTNYTNTAYAARYTNCARAARYTNAARTTYYTNGAY TCNTCNCARGTNTCNCCNATGGARYTNTCNGARGCNMGNMGNGTNGGNCCNTTYATGCAR GTNGTNMGNCCNGTNYTNGARCCNGARGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GTNGAY CCNAGYGAYGAYTCNGAYTCNGAY---TCNGGNAGYACNCCNTAYAAYGARGCNCAYGGN TTYCARCAR---TCNGGNYTNAARCCNGGNAARAARACNAARGGNMGNGTNAARATHAAR ATGGARTTYATHGARAAYAARYTNMGNMGNTAYACNACNTTYAGYAARMGNAARACNGGN ATHATGAARAARGCNTAYGARYTNTCNACNYTNACNGGNACNCARGTNATGYTNYTNGTN GCNAGYGARACNGGNCAYGTNTAYACNTTYGCNACNMGNAARYTNCARCCNATGATHACN AGYGARAGYGGNAARGCNYTNATHCARACNTGYYTNAAYTCNCCNGAYCCNGCNCCNGGN ---ACNACNTCNGCNAAYTCNYTNGARCARMGNATGAAYCCNTCNGGNTTYGARGARACN GARYTNTCNTGYGTNGTNGGNGARGAYGAYCARAARGCNTAYGARGAYTGY---AAYAAR CCNGTNTTYCCNGTNCARCARCARCCNGCNACNCCNACNCARAAYYTNCARGAYMGNACN ATHTTYAAYTTYTCNCARCCNCCNGCNGCNATHTCNATGACNCARGCNGAYCARATHGGN ACNCARCARTTYATHACNATHCCNGTNCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GCNCARYTNMGNGARACNATHCAYAARTGYACNGCNGAYGTNAGYATHCARCCNAAR YTNAAYCAYYTNACNCCNYTNGARGTNTAYYTNYTNMGNTAYCCNGARAGYYTNGGNAAR ATGATGAGYATHATHGARGARGAYAAYGCNCARYTNAARMGNYTNYTNGARTGGAARGAR AARGAYCAYGTNTTYTGGGARTGGGTNGAYAGYATHYTNACNYTNCAYATHCARGAYGGN GAYAGYAAYATHAAYGTNCARGARGAYTTYGARGARGARACNGTNTTY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARTGGTTYCAYCCNGAYGGNACNCCNACNAAYYTNTCN GTNATH---TCNTGGGARGTNYTNACNCAYAARCCNACNGTNGAYMGNGTNAGYCCNATH AAYGCNAAYYTNGAYTAYGARAGYATHYTNTGYYTNCCNGCNAARTCNTCNGAYGGNAGY YTNCCNCCNYTNATHGTNTTYGCNCAYGGNGGNCCNCAYGTNGCNTTYGAYACNTCNTGY AAYATGATHACNAAYYTNTTYTGYYTNTGYGGNTAYGCNGTNYTNATGGTNAAYTAYMGN GGNTCNYTNGGNTTYGGNCARGAYAGYGTNGARTCNYTNYTNGGNGCNATHGGNGAYGCN GAYGTNAARGAYGTNGARAGYGCNATGGTNACNGCNGTNGCNAARGGNGTNGTNGAYGGN AAYMGNYTNTTYATGTTYGGNGGNTCNCAYGGNGGNTTYYTNACNACNCAYYTNATHGGN CARTAYCCNAARACNTTYAARGCNGCNTGYACNMGNAAYCCNGTNACNAAYYTNGTNTCN ATGTGGTCNGTNAGYGAYATHAARGAYTGGATHTTYGTNGARGGNGGNTTYCCNTTYGAY ATGACNACNYTNGCNGAYGAYAARAARYTNCCNGARYTNTGGAARMGNTCNCCNATGTCN TAYGTNGAYCARGTNTCNATHGARTAYTAYMGNAARGTNCCN------------GTNMGN TGY------------------YTNGTNGAYGTNGARATHGAYTGYYTNATH------AAY ACNATHGTNTGGTAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TAYTCNTCNACNACNAGYYTN GCNGAYGCNYTNGCNTAYACNYTNYTNGGNGCNAAYMGNCAYCARTTYGCNATGCARMGN YTNTGGGGNGCNYTNGGNATHGGNACNTGYATGACNAAYGCNGCNGTNAGYTTYGGNYTN CAYGAYYTNACNGTNYTNTTYATHATGTGYYTNTGYYTNACNTTYYTNGCNAGYATGGTN GTNYTNTTYYTNAAYACNGARAGYGTNGAYAARACNAAYGAYYTNYTNMGNGAYYTNTGY GCNGTNYTNTCNAAYCCNCCNTTYMGNYTNGTNYTNGGNAARYTNYTNYTNTTYGGNYTN ATGGCNGGNGCNGCNCARAAYTTYTTYATGTGGTTYATHGCNGAYATHGGNGGNTCNCCN TTYAAYYTNGCNYTNACNGTNGTNATGAAYTGYATHTCNTCNATHTTYATGYTNMGNYTN ACNGGNYTNYTNYTNCARMGNTTYGGNMGNCARGTNGCNATGTAYACNGTNYTNGTNGCN TAYTGYATHMGNTTYYTNGCNATGTCNTTYATHGARTCNCCNTGGATGGCNYTNCCNATH GARYTNYTNCAYGGNATHACNTAYTCNYTNYTNTGGGCNGCNGCNTCNGGNACNACNAGY GTNYTNGCNCCNCCNGGNACNCARGCNTCNTGYCARAGYATHGCNGGNGCNATHTAYTGG GAYYTNGGNMGNGGNYTNGGNGTNYTNATGACNGGNCARATHGTNCARGARATGGGNGCN MGNTGGACNTTYMGNTCNTAYGCNATHGTNTGYGCNGCNTTYCCNYTNTTYTAYGTNYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGATHMGNGAYGCNGARCCNCARGCNYTNCARGTNGAYTTYCARACNATH TCNTTYGGNGAYGARYTNCCNTCNGTNAGYYTNGAYYTNGCNGAYGTNAAYATHTCNTCN AAYGARTTYGARCARYTNYTNYTNCARAGYYTNAARGAYGTNCCNYTNTCNYTNGAYTGY TCNATGGAYTGYGAYGGNCCNGTNCARAAYGARGTNGAYACNCARCCNYTNTCNGARYTN AAYATHTTYGCNGARGAYTCNTCNAARTGYAAYAAYYTNAAYYTNTCNGCNCCNACNGAR ACNAAYTTYATHTCNTTYTTYAAYTCNGCNGGNYTNGTNCCNACNCCNCCNTCNTCNGAY ATHACNCCNCCNYTNTCNGGNGGNAGYACNCCNCARAGYCARTCNMGNGCNGCNTCNCCN GCNTGGAGYGARAGYAGYGGNAGYATGAGYACNAGYAGYGTNTCNGGNYTNTCNTGYCCN MGNAARGTNGAYTCNAGYGARGGNAAYCCNYTNCCNMGNCAYAARMGNCCNTCNCAYMGN MGNGCNGARGTNAARMGNMGNGAYAARATHAARACNTGYYTNGAYGARATHAARATGAAY GTNCCNTCNYTNCARGARAARGGNAARYTNAGYGARTCNGCNATHYTNTTYAARGCNGCN GARTAYATHCAYCARYTNAARGAYGGNTTYTCNGARMGNGGNAAYAARACNGCNGARYTN MGNMGNAARATHCARAGYYTNAGYGARGARATHCARNNNTTYCARGARATGYTNCCNGTN GGNGGNYTNAARCARGARGARGTNCCNCAYCCNGAYYTNGAYCARYTNTAYACNGAYTGG GTNGCNCARCAYAAYAARATHTCNACNAARCAYTAYATHTTYCAYTCNATHACNTCNAGY YTNTTYGAYTCNTTYAARTCNGTNATGGGNGAYGTNAGYACNTTYGAYTCNATGGCNTCN AARYTNAARGARTGGCARACNMGNTGYYTNAGYYTNCCNGTNYTNMGNAARCARATHYTN AAYGGNATGYTNAARYTNACNMGNAAYMGNAAYGTNGTNACNATHTCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ACNTCNAARAARTTYYTNTTYCARGCN TGYGAYATGGAYTGYTTYGGNGTNCCNGGNCCNYTNGARGAYAAYTTYATHGGNGCNTGY YTNGAYTTYATGMGNATHGCNACNTTYYTNYTNTTYGTNTTYATHGCNGTNATGGCNTAY GGNAGYATHTAYTCNGTNTCNCCNACNAAYCAYYTNTTYATHACNYTNGTNACNGGNYTN GTNCCNYTNGTNYTNMGNAAYGTNTTYAARGARAARGGNGARGAYGARATGGTNGAYMGN ACNTCNTTYMGNTAYGARGCNCARYTNGAYCARACNATHCARTCNTTYGTNCARAGYTGG CARYTNMGNGAYATHGTN------------------------------------------ ---------------------------------------------TCNAGYAARTCNTCN CCNTAYCCNACNCCNGTNCAYACNTGYGAYMGNCAYAAYMGNAAYCAYMGNCAYAAYGAY GTNMGNCAYCAYMGNTCNCCNAAYCARAAYATHAGYGAYMGNTAYYTNGAYGAYGAYCCN TCNYTNGARGCNTCNGARTCNATHCAYAGYTTYAAYTCNAGYGARGAYGARTTYAAYTGG CARACNGGNCARGARGARGGNGAYGARAARYTNTCNYTNCCNGCNCAYYTNAAYCARTCN YTNTCNGAYYTNCAYTTYMGNCARAGYYTNATGCARMGNATHCARGARTGGTCNAGYTTY GCNGARGARTAYAAYAARTCNTTYTCNCCNACNCCNGARAGYTCNCCNATHMGNTTYATH MGNMGNAGYMGNTCNYTNGAYMGNCAYYTNGGNGAYGCNTCNGTN---GCNACNGARTCN GARATHCCNTCNTCNAARCCNYTNGARATHGARCCNGTNACNGARAARAAYYTNGARACN YTNGARTAYGARYTNCAYGAYATHCARGGNGARTTYGARTCNATHACNTCNAARYTNCAY GAYYTNATHGARCARGGNGGNACNACNCCNYTNTCNCARGCNTCNTCNTCNTAYCCNGCN GCNTCNACNAAR---------------AARTCNACNYTNTCNTCNTCNAAYAAYMGNACN ATGCCNYTNTAYMGNGAYTCNTCNTCNACNCCNCAR------------MGNGTNGARAAY AAYAGYACNCCNACNATHMGNAARATGAARACNAARTGGGARMGNGTNCCNGGNTCNGCN TGYTCNGAYTGYAGYMGNAGYTCNMGNGGNAGYAGYGTNGARTAYGTNTGGGAYYTNGCN GAYTAYTCNCCNCAYTCNACNGTNTCNMGNGGNGGNTTYCCNTCNACNGAYYTNTGYCCN GTNGAYGCNTCNGAY---MGNGTNTGYAAYATHAAYAAYCCNGTNTCNGTNYTNGARTAY TGYCARMGNGARTGGAARGGNGAYACNGTNAARGCNMGNACNATHMGNGARGGNTAYCAR CARATHCCNTCNMGNATHCARTGYAARMGNATGTGYGTNATHMGNGGNGAYAAYTAYTGY GCNYTNMGNAGYACNYTNTTYCARGTNYTNGTNAAYGGNCAYMGNATHGTNCCNAGYTCN TGGGGNATHATHGGNATHATGGAYMGNYTNCAYAGYCAYTTYGARGAYYTNACNATHCAR ATGTCNTCNTGGAGYTTYGCNAAYMGNYTNCCNGGNCAYTGYAARGAYAARYTNGCNTCN ATHTCNAARTGYGCNYTNTCNYTNTAYGCNACNGTNGARGARGTNTGYAAYYTNCARACN MGNGARGARMGNGARAARMGNACNATHAAYYTNTTYAAYGCNAGYTCNACNTTYGAYYTN GARYTNATGGARGGNYTNAARGTNATGATGYTNYTNCARYTNGTNATGYTNMGNCARAAR ATGYTNGAYGGNGARGAYATHCCNYTNTTYGGNCAYYTNYTNTTYGCNMGNGAYACNTCN GARTCNGTNGCNGAYTTYATHAARAAYCAYYTNAAYTGYATHGGNGAYTCNGGNGGNYTN GARCARGTNGARATGTGYYTNYTNGGNTAYACNYTNGGNGTNAGYATHMGNGTNATGMGN YTNTCNCARTTYGGNCARGARGAYTTYGARTGYTGYYTNCCNGAYGAYYTNCCNYTNGAY ACNCCNCARGTNGTNYTNATGGCNGARGAYGAYMGNCAYTAYAAYGTNCCNYTNCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNGTNAGYTTYGARAAYACNGGNACNAARGARGTNTGGTTYGARGTNYTN AARYTNCCNGTNGARAGYTGGYTNAARGARYTNGARACNATHCARGCNGCNATHACNAAR CARAARGAYGARAAYGARAARGARGCNGCNGGNCARGGNGGNGARGCNGAYCARGARCCN ACNTCNAARCCNGTNGARGARACNAARATHAAYGARTCNTCN------------ATHAGY ACNGAYTCNGTNATHGARAARATHGGNACNAARTTYAGYCAYCCNACNATHGTNTTYAAR GCNAARCCNCCNCARMGNYTNCCNYTN---CCNAAYACNTCNTCNAGYATHGGNTCNGCN GTNTCNAARGTNGAYCARGGNGAYGTNYTNGGNACNGGNACNAGYCAYGTNYTNAGYGCN TTYCAYYTNGARTCNMGNGAYGCNATGTTYAAYCAYCAYTAYGAYAGYYTNYTNAARTTY YTNCCNTCNGARGARGARGARAAYCCNATHTCNGTNACNTTYCAYTTYACNAAYACNAGY MGNATGATHCCNATHGGNATGGARCARTCNACNCCNCCNAGYAARCCNGTNTCNGTNGTN YTNTGGTGGTCNGAYACNCARCAYATHTGYCAYTAYTCNYTNYTNAARACNGCN---AAR GAYATHGARTTYAARCCNGAYATHGTNTGGCCNTGYTCNGAYATHATHAGYTGYTCNACN YTNAGYCCNTGYGGNTCNCAYATGGCNATHGGNYTNGCNAAYGGNAAYGTNGCNYTNTGG GAYTAYCARATGGGNGTNCCNAARGCNGTNYTNACNGTNTGYGGNAAYGGNGGNGTNAAR GGNYTNMGNTTYYTNGAYCCNAGYYTNTTYCCNTCNGAYCCNCCNCAYTAYCCNCCNTAY CCNGTNTCNTCNGCNACNTTYATHYTNGCNGARTAYTGYGAYGGNACNCARGCNYTNTTY GAYACNTGYGAYGGNAGYCARCARATHCCNMGNACNATHGCNTCNGTNCCNGARAAYGAY GAYGAYGTNCARACNYTNATHAARGTNATHCCNGAYYTNCCNGARYTNATGYTNTTYGTN AARAARAAYGGNTCNATGTAYATHAARGAYATHGGNACNGGNGCNACNYTNTGYCARGTN TGYYTNCCNCCNACNCAYGCNATHCARACNCCNTGGAAYCCNATHTTYGCNATHGGNGCN GGNGGNCAYGTNGTNTAYYTNAARGGNGARGGNAARGAYGTNAGYGARGAYGGNGARGTN AGYGAYATHTCNTGYYTNTTYAARTTYAAYYTNMGNGARTAYTCNATHYTNGARGARTAY TGGACNMGNCCNMGNGARAARTCNGARYTNATHGTNTAYACNACNTGYGARCARMGNYTN GAYTCNYTNATGAARGARMGNYTNCARCARCARGCNATGMGNAARCCNMGNATGCARAAR CAYTGGGGNCARYTNMGNGGNGARYTNGAYATHATHCARAAYGCNMGNCARATHCCNATH GAYACNYTNMGNYTNTCNMGNYTNGGNCAYATHATGCARATGTAYGARGAYYTNGTNGGN YTNACNGARGTNAARACNGCNCARGARAAYGTNGTNGAYGCNGARMGNAAYTTYYTNAAR ATHCARGARGAYMGNMGNACNYTNCARCARGARYTNACNGARATHCARGCNGARGTNMGN ACNGTNGCNACNGARYTNGARAARACNCAYMGNACNGAYCCNTGYTAYATHGAYYTNGTN AARAARGARCAYGGNATHYTNGTNATGGARAARGARATHGTNAAYAARYTNAARACNYTN GAYMGNTGYGARMGNGAYYTNTTYTCNGTNYTNAGYATGTGYGTNMGNGARAGYCAYGAR AARGARMGNGCNMGNGCNGARMGNACNAARTAYTGGTCNATHATHGGNTCNGTNATHGGN GCNATHATHGGNATHACNGGNTCNACNYTNAAYAAYCAYAARMGNYTNAARGARATGMGN TCNATHGTNAARGARTCNGGNGARAAYAGYGCNGTNTAYAARGAYATHGCNGAYAARGTN ATHGCNACNATHTCNTCNTCNTCNYTNACNYTNMGNTTYATHGCNGAYAGYGTNACNGAY CAYMGNTCNATHGGNTTYMGNGTNATGGTNYTNTAYAGYACNAGYCAYAGYGARYTNCAY YTNMGNATHCAYGAYGTNAARAARTCNGARGARGGNAARCARAARGARAGYAGYAAYTCN CAYCARCAYATHATHGTNGCNGGNACNYTNGGNGTNYTNATHGTNATHGTNGTNGTNGTN TTYGCNYTNYTNATGGGNMGNCARMGNGCNCCNGCNTAYGCNACNCCNCCNGCNTGYYTN CAYMGNGTNGGNYTNGARTCNAGYTCNACNGGNTCNTCNTTYCCNGCNGAYTTYACNAAR CCNGTNCCNYTNGCNGTNGTNTCNCCNGAYGGNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYGAYGAYGAYGAYTTY TAYGAYGARGARYTNCCNGARCAYCCNCARCCNACNCARTGGGAYAAYGGNACNCCNACN ATHGGNAGYMGNGGNTAYAGYGGNAARGGNAARAGYATHGTNACNAARCAYGAYAARGTN ATHTGYGGNMGNMGNAAYGCNCARMGNYTNATGCARTTYCCNCCNGAYTTYGGNTGYGGN GAYGGNGARGGNATGGAYATGCARYTNCCNAAYMGNGTNTAYAAYAARYTNAARAGYCAY TCNCARTCNGARAAYAARAARAGYCAYAARGTNYTNGARAARAARGAYCAYTCNACNGCN ATHAARGCNGTNGAYGARAARACNMGNATHYTNATHTTYAARATGATHAAYGCNGARTTY YTNACNTCNGTNGAYGGNGTNGTNAGYGARGGNAARGARGCNGTNGTNYTNAARGCNATH GGNGGNAARMGNGAYGAYGAYGARYTNCCNAARGAYGTNATHYTNAARGTNTAYAARACN TCNATGAAYGARTTYAARACNMGNYTNAARTAYATHMGNGGNGAYTAYMGNYTNTCNAAR GAYYTNTTYAARAARTTYAAYCCNMGNAARGTNATGMGNATGTGGGCNGARAARGARTAY YTNAAYYTNAARAARYTNMGNMGNAAYGGNATHCCNTGYCCNGGNGCNYTNGCNYTNAAR AARCAYATHYTNGTNATGGCNTGYGTNGGNGGNGARAARCCNGCNCCNAARYTNAARGAY GTNYTNYTNAAYACNACNGAYYTNCARGAYGCNTAYGARCARACNGTNAAYYTNYTNAAR ATGATGTAYCAYAARTGYAAYYTNGTNCAYTCNGAYTTYAGYGCNTAYAAYYTNYTNTGG CAYGAYGGNAARGTNTGGGTNATHGAYGTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATHMGNCAYACNAAR ACNCARCARYTNTCNACNTAYATGACNMGNTAYTAYACNCCNGTNAARGTNGGNTGYTCN AARYTNYTNTCNGCNAGYYTNAGYCCNTCNGGNAARGARYTNGTNTTYGTNYTNYTNTTY CCNGAYTTYCCNCCNAARGAYGCNCAYYTNATGGTNYTNGTNYTNGARYTNGCNTCNGTN AARYTNMGNAARTTYMGNTAYGAYCAYCCNGTNACNGARCARCARCAYAARGARGTNTCN GARAARYTNGTNTGYTCNGCNGCNATGAGYCARACNTAYGGNCCNACNGGNGCNGAYTAY YTNTTYYTNACNGTNGGNGGNGARTTYGTNTGYGTNTCNYTNGCNACNGGNTGYGGNGTN YTNMGNATHGAYAAYCCNTCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARATHATHAARGTNATGTGGMGNAARGGNAARTCNMGNGAYGTNAAYMGNGAYGAR TGGCCNAARTCNAARAARTCNTGYMGNTAYGTNMGNTTYGTNYTNTAYAARGARAAYAAR GAYACNATGGAYGCNATHGGNYTNATHGCNAARAAYYTNAARGTNMGNGARAGYATGTTY CARTAYGCNGGNACNAARGAYAARMGNGCNAARACNACNCARGARATHACNGCNCAYMGN GTNCAYCCNAARAARYTNTTYAAYYTNAAYAARGTNYTNTGGAAYATGGGNYTNGGNGAY TTYMGNTAYGTNCARCARCCNYTNCARYTNGGNCARYTNTCNGGNAAYMGNTTYACNATH GTNYTNMGNAAYGTNCAYGCNAGYCAYAARGTNGTNGAYTCNACNYTNACNTCNYTNAAR YTNACNGGNTTYATHAAYTAYTTYGGNATGCARMGNTTYGGNACNACNTCNATHCCNACN CAYCARATHGGNAGYACNYTNYTNAARGGNGAYTGGGARAAYGCNATHGAYYTNATHYTN GCNCCNMGNAAYGAYGTNCCNGCNAARGAYAARTTYCARAARACNTGGGCNGARACNAAR GAYCCNGCNGTNACNYTNGAYGTNACNCCNMGNTAYTGYGGNYTNGARMGNAAYATHYTN GARGCNYTNMGNAARAARGCNAARCCNTTYAAYGCNYTNGARAARYTNCCNMGNAAYACN MGNYTNYTNTAYYTNCAYAGYTTYCARTCNYTNGTNTGGAAYCARATGGCNTCNAARMGN YTNAARGARYTNGGNCARGGNGTNGTNGCNGGNGAYYTNGTNATGATHAARGAYGGNCAR GAYTCN---------------------CCNAARCCNATHGTNGTNACNGARGARAAYGCN AGYAAYTAYTCNYTNACNGAYATHGTNYTNCCNYTNCCNGGNCAYGAYGTNATHTAYCCN CAYAAYCARGTNGGNGARTGGTAYAARGARYTNYTNGCNTCNCAYGAYYTNGAYATHGAY AAYATGAARMGNCCNCARAARGAYTAYTCNYTNCCNGGNGCNTAYMGNCAYYTNGTNGTN ATHCCNAARGAYGTNTCNTGGGARCAYMGNTAYTAYAAYGAYTAYACNCARCCNYTNACN YTNAGYGAYTTYGAYCAYATHCARGGNGARACNYTN---CAR---GGNACNGAYACNGGN AAYYTNTCNGCNGTNATHYTNCAYATGTCNYTNCCNTCNTCNTGYTAYGCNACNATGGCN YTNMGNGARGCNATGMGNGTNGAYACNTCNTCNTTYCAYCARGCNTCNYTNAAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATHTTYTCNCCNCCNAARGGNATHYTN---ATGGCNGCNGARYTNCCNYTNTTYCCNAAR GCNACNTCNATGTAYYTNCAYAGYGGNAAYATGATHAAYTGGAAYMGNYTNAARMGNAAR CCNAAYYTNTCNTCNTCNGAYGARYTNTGYGARGTNATHGGNGARACNYTNGGNTCNTAY YTNGARGCNGCNAAYAARACNGARYTNCARTAYATHACNGARGTNTAYAARATHAAYACN GARAAYGTNGARYTNATHGARGARAGYGARMGNGGNGAYGTNAARATHACNGTNAARGTN TTYATHTGYGAYTCNCARTCNCCNACNGTNATHAGYGAYGCNGTNGGNAARGTNYTNAAY GARYTNGGNACNACNTTYGTNGARACNYTNYTNYTNGCNGTNTGYCCNAGYGGNGGNGAR GAYCARGAYCCNGARGARGTNGTNAGYYTNTCNACNYTNCARMGNTAYTGGCARGCNATG GARGARYTNGTNGCNAAYGAYAARGTNYTNTCNYTNGGNATHTGYGAYYTNGGNAARGAR GGNYTNGARGCNYTNTAYAAYTGGGCNCARGTNAARCCNTGYGTNAAYCARGTNAAYYTN GARTCNTGYTGYGTNYTNCCNAARGAYYTNACNGARTAYGCNAARGCNATHAAYATHCAR YTNYTNACNCAYAAYGAYMGNCCNGCNTTYATHACNAARGARYTNYTNCARGARAARATH CARAGYGTNGCNACNGARMGNGAYAGYGAYGCNTGGACNCCNGARTGGGTNGTNMGNTAY TCNGGNATHYTNAARTGYMGNGGNATHATHAARACNAARGGNTAYATHTTYCAYGCNACN MGNGAYAAYAARAARMGNATHYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GGN GAYGAYCARGTNGARAAYGGNAGY------TCNGAYMGNAARAARAARMGNMGNAGYMGN TGGAAYACNGAYAAYGAYGARAARACNGTNATHCCNGGNATGCCNACNGTNATHCCNGCN GAYYTNTCNGARTCNCARCARMGNCARTAYGTNGTNCARYTNCARATHGARGARATHACN MGNAARYTNMGNACNGGNGARYTNGGNATHCCNTCNAAYCCNGARCARMGNTCNCCNTCN CCNGARCCNATHTAYAAYAAYGARGGNAARMGNYTNAAYACNMGNGARTAYMGNACNMGN AARAARYTNGARGARGARMGNCAYMGNYTNATHCARGARGCNATGAARYTNAAYTCNGAR TTYAARCCNCCNAGYGAYTAYAARCCNCCNGTNATHMGNGTNAAYGAYAARGTNATGATH CCNCARGARGARCAYCCNGARATHAAYTTYGTNGGNYTNYTNATHGGNCCNMGNGGNAAY ACNYTNAARACNYTNGARAARGAYACNGGNGCNAARATHATHATHMGNGGNAARGGNTCN GTNAARGAYGGNAARATHGGNMGNAARGAYGGNCARCCNYTNCCNGGNGARGAYGARCCN YTNCAYGCNTAYGTNACNGCNAAYAAYCCNGARAAYGTNAARAARGCNGTNGARCARATH AARGARATHATHAARCARGGNATHGARGTNCCNGARGGNCARAAYGAYYTNMGNMGNCAR CARYTNMGNGARYTNGCNYTNYTNAAYGGNACNYTNMGNGARAAYGAYGGNYTNCARAAR YTNMGNCARATHGCNGARAGYCARACNATHGTNACNAAYACNATHGTNTGYACNGTNTGY GGNGGNACNGGNCAYATHGCNCARGAYTGYAARCARAARMGNCCNGGNGAYACNTTYMGN ATGCARCARATGCARAAYCCNGCNGAYMGNGCNAARATGGAYAGYGARTAYATGTCNYTN ATGGCNGARYTNGGNGARGGNCCNCCNCCNCCNAARAAYAAYTTYGGN------CARAAY ---------------CARCARCCNCCNTTYAAYMGNCCNYTNYTNTCNAAYCCNCCNCCN AAYCCNATGGCNATHAAYTCNCCNTGGCARATH---CCNGCNAAYMGNCCNCCNATGTCN AAYCCNGTNCCNCCNCCNCCNTCNAGYTCNGGNCCNCCNYTNYTNAAYMGNCCNCCN--- ---ATGTCNACNACNGCNCCNCARATHAAYCCNATGGGNMGNYTNCCNATGCCNYTNATG TCNTCNCCNYTNCARTCNCAYCCNGGNATGCARGCNCCNGGNGCNYTNYTNCCNCCNCCN GGNCARCARCCNCCNCARCCNCARCARATGGGNAAYATGCARCARCCNCCNCCNCARCCN CARCARCARCARCARCARCAYCCNCARCARCARCARCARCARCARCCNYTNMGNCCNTGG CARCARCCNGCN---AGYCARGCNCARCCNYTNATGAAYCARGGNGGN------------ ------------------ATGCARTCNAGYGTNAGYATGGGNYTNCCNCCNCCNCCNCCN TCNATGATGAAYGCNCCNCCNCCNCCNCCNGTNAGY---------ACNGGNCAY---CAR GCNCCNCCNCCNTGGATGCARCARCARCARCARCARCCNGGNAAYATGGGNATH---CAR CARCARCCNCCNCCNCCN---CCNCCNCCNACNTCNACNGCNCCN--------------- ------------------GARTGYGCNGGNGTNCARATGGTNCARGAYGTNGAYGGNTCN AAYATHAAYGTNGTNGGNTCNGAYAAYATHCCNACNATHGTNYTNCCNCARACNTCNGCN TCNTCNAAYCCNCCNCCNGGNTGYCCNGCNTGGGCNGCNMGNYTNYTNAARTGYGARAAR ATHGGNGAYTCNTAYMGNGGNTAYGTNGARAAYGARGTNAAYYTNGAYATHATHYTNACN YTNCAYAARCARCARACNAAYAGYTTYTGGGGNACNMGNCARTCNCCNAGYACNGCNAAR TCNTCNACNMGNYTNATGTGGAARTCNCARTAYGTNCCNTTYGAYGGNATHCCNTTYATH AAYTCNGGNAGYMGNGCNGTNGTNATGGARTGYCARTAYGGNCCNMGNMGNAARGGNGCN AARAARACNCAYTAYCCNACNGAYAGYAAYGGNTTYMGNCARACNTGYCCNGCNMGNATH TAYGTNAARAARGTNMGNCCNACNTAYGCNGTNAAYYTNAAYATGGAYAARAARAGYATH MGNYTNGCNATGGAYAARGCNTTYCAYGARYTNMGNGARAARGGNACNGAYGTNTGGGGN GARGAYMGNTTYTAYGTNCARYTNCCNACNGARGARGCNCAYGAYTAYCAYGARACNGGN TCNACNYTNTCNAARCAYATHYTNYTNGCNGTNACNGARGTNGARAAYMGNATHCAYCCN MGNGTNYTNGARCARATHMGNGTNATGGTNGCNGCNGGNGARACNAARYTNTAYGCNATH MGNAARCARYTNMGNAARTTYGTNGTNMGNGARYTNTAYMGNGGNTCNMGNCARGCNCCN GARMGNCAYGAYYTNACNGTNTTYCCNACNGTNAAYGAYYTNAARAAYCAYATHCAYCAR GCNYTNACNGAYATHCARAAYGGNACNYTNCARATHCCNACNATGGARGTNCARATHGAY TGYATHGAYTCNCARGAYAARGGNGCNGTNGARAARGARGTNAARAGYGARGAYAARTCN GARYTNTCNTCNTTYTGGTCNGGN---GCNATGCCNGARACNGTNACNGTNACNYTNACN CARAAYCCNGAYYTNGARATGGAYGARAAYGAYAAYAGYTTYCCNTGGGGNYTNATHCAY CAYAAYGARYTNGCNACNATGYTNACNAGYGGNYTNGGNAARACNGTNGTNATHGAYAGY MGNTCNTTYYTNGARTAYAAYACNAGYAAYATHCARCARTCNGTNAAYGTNTGYTGYTCN AARYTNGTNAARMGNMGNYTNCARCARGAYAARGTNCAYGTNGTNGAYYTNYTNAAYCAR ACNTGYAAYGTNGTNGCNGAYTCNAGYTGYGAYGTNATHGTNTAYGAYCARTGYACNGAR GAYGCNAAYYTNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GTNMGNAAYGTNGTNTTYATHAARACNCAYAARGCN GGNAGYTCNACNGTNGCNAAYGTNYTNCARMGNTTYGGNYTNTCNCAYAAYYTNACNTTY GCNYTNCCNAAYAARCCNYTNAAYACNTTYGGNTCNAAYTAYYTNATHMGNCCNGGNGAR GTNYTNAAYAARAGYGCNYTNYTNCCNYTNCCNGARGGNMGNAARGARTAYAAYATHYTN TGGAGYCAYAGYATHTAYAAYMGNAGYACNTTYCAYCARGTNATGCCNAAYTCNACNGTN TAYGTNTCNATHYTNMGNGARCCNTTYCARCARTTYGTNTCNACNYTNGARTAYTAYGGN YTNGCNAARTCNYTNGCNAARATGAAYATHAGYAARAARYTNATHTCNAAYCCNGTNTCN GTNTTYYTNCARACNCCNAARTTYTCNAARTAYMGNAAYAARAARTAYGGNTAYYTNMGN AAYAARCARGCNCARGAYYTNGGNTTYGGNYTNGCNCARTTYYTNGARACNGAYAARATG AARAGYTAYATHGAYCARYTNGARAARGAYTTYACNAGYGTNATGATHATGGARTAYTTY GAYGARTCNATHYTNYTNYTNMGNCAYAARYTNTGYTGGGARATHMGNGAYATHYTNTAY ATHCCNAARAAYAARAAYATHAAYAARCCNMGNMGNGGNGAYAARATGGAYCAYAARMGN AAYACNAARGARATGATHGGNGGNTGYTGYGTNTGYTCNGAYGARMGNGGNTGGAGYGAR AAYCCNYTNGTNTAYTGYGAYGGNCARGGNTGYAAYGTNGCNGTNCAYCARGCNTGYTAY GGNATHGTNCARGTNCCNACNGGNCCNTGGTTYTGYAARAARTGYGARTCNCARGARMGN ATHGCNMGNGTNAARTGYGAYYTNTGYCCNCARMGNGAYGGNGCNYTNAARMGNACNAAR TCNGGNGGNTGGTGYCAYGTNGTNTGYGCNYTNTAYATHCCNGARGCNTGYTTYGCNAAY GTNCARACNATGGARCCNATHGTNYTNACNTCNGTNCCNCAYGARMGNTTYAAYAARACN TGYTAYATHTGYGARGARCARMGNMGNGAYACNAARGCNACNGCNGGNGCNTGYATGCAR TGYAAYMGNAAYGGNTGYAARCARTAYTTYCAYGTNACNTGYGCNCARGCNCARGGNYTN YTNTGYGARGTNACNGGNAGYTAYGARAAYGTNAARTAYTGYGGNTAYTGYTCNCAYCAY TAYAARAARYTNAARAAYYTNTCNAAYGTNAARACNATHCCNGCNTTYMGNCCNATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TGGATGTGGCARCAYGTNTCNYTNACNTGGYTNAGYTCN YTNYTNATGYTNACNGCNCAYTTYYTNCCNCCNCAYTAYYTNCAYYTNYTNCAYAARAGY GCNMGNCAYYTNGGNMGNTGGCARMGNATGGARGCNMGNCAYGCNCAYGTNCCNTAYAAY GCNTGGTCNGARYTNCARGTNTGGCCNCARGGNGCNYTNGTNAARCAYGTNMGNGGNYTN TTYAARGCNGARGGNATHAAYGTNACNGCNGARCCNGGNAAYAGYYTNCAYAGYMGNTTY TTYYTNYTNTTYCAYCARCCNATGMGNGTNATGAAYTGGYTNGTNTTYYTNACNTGYYTN YTNATGGCNTAYCARGCNYTNMGNYTNGTNCARAGYTCNGARTGGAGYCAYATHATHTCN YTNGCNYTNYTNATGTTYTGYAAYTTYTAYACNYTNTTYAARYTNATGMGNGAYTGGTTY ATHATGGGNAARGTNTAYAARGARCAYGAYTAYGTNGTNTCNAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GTNGARAGYTAYGAYCCNTCNGAYYTNTAYGAYGAYGCNGTNTCNYTN TCNGARAAYYTNACNAARTAYGAYTGGTTYCAYGGNGAYATHAAYMGNAARGARGGNGAR MGNMGNGTNCARTCNGTNGGNAARATHGGNACNTTYYTNATHMGNACNTGYTCNGGNAAY ACNGGNAAYMGNTAYCCNTAYACNYTNGTNATHAARACNAARGAYGARGTNAARAAYYTN MGNATHMGNCARMGN---CARGAYAAYAAYTTYGCNYTNGGNACNGARMGNGCNGAYGAR ATHTGYTTYCCNTCNATGTGYGARYTNGTNCARCAYCAY---------------TCNAGY YTNAARATGATHCCNTAYATGACNGCNCCNGGNCCNGCNGARTCNGAYAAYGAYACNTTY TCNCARTAYMGNCAYMGNTTYTCNATGCCNYTNACNGARTGGCCNATGACNCCNGAYMGN ATGTGGTAYAGYATHGAYYTNGGNCCNGTNCAYYTNGTNAGYTAYTCNACNGARGTNTTY MGNTCNGAYGGNAARTAYGCNCCNACNCARCAYAAYTGGYTNATHAARGAYYTNGARGTN GCNAAYTCNAAYMGNCARAARACNCCNTGGATHATHGCNTTYGGNCAYTGYCCNATGTAY TGYGCNAGYCARGAYCCNGCNYTNACNTGYAGYAARCARAARTCNAARATHGCNCARGAR YTNGARGAYATHATGTAYCAYTGGGGNGTNGAYGTNATHGTNTCNTCNTCNGGNYTNGGN AAYGARATHTCNTAYCCNATGTAYAARGGNGTNAARGTNGGNGAYGAYTTYMGNCAYCCN YTNGCNCCNATHCAYATHAGYGTNTCNTCNGCNACNCCNTGGAARGCNAARTAYAAYTCN ACNGARGAR------GARTGGYTNCAYTAYTCNGAYAAYGAYGAYACNCCNATHAAYTTY GGNMGNYTNCARATHCAYAAYTCNAGYYTNATHMGNTTYGARATHGTNTCNTTYGARAGY TAYAARGTNATHGARTCNGTNGARATHGTNCARCAYGAYCAYAARAARTTYTCNAARGAY GAYYTNCCNGCNAAYATHTCNGCNAARATHAAYAARGARATHGARGTNTCNGGNGGNGAY CCNGGNTCNATGAAYATHGARGARACNACNAGYAGYACNATHTCNAARAARATHAGYGAR ATHYTNCARGGNGAYAAYMGNAAYAARATHATHATHGGNGTNAGYGTNGCNGGNGCNATH YTNYTNGTNGTNGTNGCNYTNYTNATHGTNMGNMGNGTNATGMGNGGNMGNMGNMGNCAY TCNTCNMGNMGNTGGGARAAYATGGAYATHAAYTAYGGNAARMGNTAYTAYAAYAARGCN CCNGARAARGAYGAYYTNGARAAYGAYTTYGARATHGAYATGGCNGARACNACNGCNTCN MGNAARYTNYTNTCNGAYGAY--------------------------------------- ------------------------------------------------------------ ------------------------------------AGYCARATHCAYACNYTNCARGAR GARAAYMGNMGNYTNCAYGAYGAYYTNACNMGNGCNMGNCARAARTGYGARGAYAARAAY CARMGNATHACNCARYTNAARAGYGAYYTNGARMGNCARAARAARAARGARGCNGARGAR ACNGCNGTNATGGARAARGCNGTNYTNCARGTNGARGARAAYYTNGTNACNACNACNCAR MGNGCNGTNCARGCNGARTCNGCNGTNTCNAARYTNAARCARGARGTNAARGTNYTNCAR AAYCARGTNMGNTGYYTNTCNGCNGARAAYGARGCNTAYMGNAGYGGNGAYGGNGGNYTN TCNGAYATHMGNGARMGNACNAARTAYACNTCNGARCARYTNAARGTNGGNGCNGARGCN GCNGARMGNAGYYTNAARGAYYTNYTNYTNGGNGTNGAYAARATGAARYTNYTNTCNCAR GTNYTNGARAAYTGGGARAARATHACNGARGTNGARACNGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AAYTAYTCNATHCCNGTNTTYCARCCNATGAAYATHGCN GAYGCNCCNMGNATGTAYTAYMGNCCNTGGMGNGGNGAYAARYTNCCNATHGGNGARGTN CCNCAYCCNCARACNTCNCCNGCNTTYTAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AGYMGNYTNAAYMGNAAYYTNGAYCAYAARGTNTCNGAYGAR TCNCCNCAYATGCARGAYGTNTGYGTNTCNMGNGCNGTNCARAARGGNATGYTNGCNYTN ATHAARGCNATHATHCAYGGNYTNGGNCARACNATHACNAAYCAYGGNYTNGGNGGNATG GCNTCNGCNTAYATGGTNYTNGARGTNGCNCAYACNCAYTAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TGGATHTGYGCNAAY ATGGCNATGAARGARACNTCNAARGCNGTNGCNATHTGYGTNCAYCAYMGNGTNTCNCAR ATHCAYMGNCARATGTCNMGNGCNGTNGGNMGNMGNMGNYTNTGYACNAARAAYTGYAGY MGNATHGGNACNGAYTGGTGYTCNATHTGYGARMGNTGGTCNMGNGARATHATHGCNATH TCNGARCCNGAYTAYMGNCCNMGNATHAAYTGGTCNMGNYTNAAYTCNTCNCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GCNAARAARCCNTTYATHGCNMGNGCNMGNGARCAR GCNTTYGARACNATHTAYAARCARGCNAARYTNGAYYTNYTNCAYTTYGGNGCNAARGAR GAYAGYATHGARATHYTNGARAARTCNGAYTCNTCNYTNAGYTAYATHCCNGGNAARGTN YTNAAYATHAARATGAARGTNGTNGGNGAYATGMGNCARCCNGARGTNACNGARMGNTCN GTN---AAYCAYTGGGARAARCCNGARGGNTCNGAYAARTTYYTNCARAARGARYTNCCN GGNTGYATGAARCARACNATHACNTCNACNGGNYTNYTNATHTGY--------------- ---GAYGARGAYGCNACNCARGTNCCNAARGAYCCNTTYGTNGAYGARAARTCNGGNGAR TGGATHYTNTCNGAYTGGGAYATHGARTGYYTNGCNGTNGGNTCNGGNATHTAYGGNTGY GGNGGNGGNGGNAGYGTNCAYATHGGNAARATHMGNGCNYTNAARGCNGTNMGNGAYGGN AARAARATHMGNGTNATHMGNAAYAARCARYTNGTNGARAAYAGYGAYCCNGAYAARGAY YTNGTNTTYGCNGTNGGNATGATHGGNTCNCCNAAYGTNGCNTAYGARACNGGNTCNGCN ACNGTNGARTCNAARGARGCNGTNAARTGYYTNAARAAYATHTAYGAYATHGGNGGNTTY AARGAYGGNAGYYTNCARAAYGGNGAYGGNGTNAARATHGARGARACNCCNGARGGNTGY MGNTTYGTNACNAAYTAYAAYCCNATHCCNTTYGARAARCCNGARGARTAYAAYATHGTN GGNYTNACNTCNTTYGARTTYGCNGGNGTNAAYGCNATGGARCCNYTNYTNYTNGCNGCN GAYATGGGNATHCCNGTNATHGAYGCNGAYGGNATGTCNMGNGCNTTYCCNCARYTNGAR ATGTAYATHCCNTTYATGTAYGGNAARCCNCCNTAYCCNYTNTCNATHATHGGNTGYGGN GARYTNTCNGARAARAGYGTNYTNYTNTAYGCNCCNGAYGGNAARCARGCNGARAAYTTY YTNMGNGAYGTNAGYATHAARCAYGGNTGYYTNGCNCAYYTNGCNYTNACNYTNACNACN TCNGARATHGAYACNAARACNGCNCAYTAYGTNATHAGYAGYGCNTGGMGNYTNGGNGAY GCNGTNYTNMGNGCNMGNYTNGARAARAARCCNGTNATHGARACNATHGTNGARCARGAR AAYGGNAARCAYGTNATHACNGGNAARGTNTCNGAYGTNCARMGNGARACNAGYAGYGGN TTYAAYAARGGNAAYGTNYTNATHGARGGNATHGAYACNTGGGCNGGNCARAARATHGAR ATHGARTTYCARAAYGARTAYYTNGTNGTNTTYCCNYTNAARGAYGGNAARMGNGGNGCN CAYCARGGNTGYGTNCCNGAYYTNATHGGNGTNGTNGAYTCNGAYACNGGNGARCCNATH ACNGCNGARGARYTNMGNTAYGGNATGGTNGTNGGNGTNGTNYTNYTNCCNTCNTGYGAY ATGYTNMGNMGNCCNGARGCNYTNMGNTGGATHGCNCCNCAYGCNTTYMGNTAYAAYGAR ATGGTNTCNTTYGTNCCNTAYAARGARMGNAARMGNGTNCARCCNATHCCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYAARTGGTAYMGNYTNAARGCNGGNYTNTTYYTNACN TCNGTNACNGGNTGYTCNATHYTNGCNGGNTTYGGNYTNACNYTNGGNATGGCNAARAAR CARGAYCCNMGNCAYTTYGCNAARGGNYTNGTNGGNTCNAARGARYTNCCNGARAGYGGN GTNGCNYTNGCNACNMGNGCNYTNGCNMGNGCNTCNYTNTAYTCNGTNACNGGNTTYGGN YTNGTNTGYTTYGCNGTNTGGAARGTNATGGAYGTNCAYAGYATGGTNGARTTYMGNGAR AARATGGGNAAYGCNYTNCCNMGNYTNAARMGNACNGARAGYGCNGGNMGNAAYGARTTY GCNACNATHMGNGAYYTNTTYGARTAYATHATHGAYGARGAYAARAARGCNAARGCNATH AARGCNGARAARAAYGARGAYGARTGYGAYTAYTAYMGNCARMGNTTYCARAGYYTNAAR ATHGTNYTNGAYCARGTNGARAARGARYTNGCNYTNTAYAARMGNMGNTCNYTNGGNGTN GAYACNATHGARYTNGCNYTNAARGARTCNAARCARCARAAYGTNAARYTNYTNAARCAY ACNAARTCNYTNGARGCNGCNATHTCNATHYTNCARAARMGNYTNAAYAARAAYGGNYTN TCNATHAGYATHAAYATHCARGAYACNGARYTNTTYGTNCCNGGNGCNTCNAARCARACN YTNAAYAAYYTNGCNAARGARAAYGCNMGNYTNMGNACNYTNYTNAARCARGARAAYGGN ATHTTYGGNAARAAYTCNGCNAAYGARTTYGARGAYATHAARGCNGCNATGGARAARGCN GARTCNGARATHAGYCARYTNAARATHAARATHAARGAYGTNGARGAYGTNAARYTNAAR ATGTGYAGYGARTAYGARATHGARAAYYTNMGNAARGARAAYCARGARGARAARGCNMGN TTYGARCARGARYTNAARGCNAARGARACNAARCARYTNAARATGGAYTCNAGYTTYATH CARGAYYTNAARGAYYTNYTNAGYAARACNGCNGARMGNTGYACNCARYTNACNGARCAR YTNCCNATHTCNGTNACNGAYAAYYTNAARATHCARGARAAYAGYGCNGTNGAYGARMGN GTNCAYTCNGTNTCNCARGARAAYTTYAAYAARYTNGARACNMGNYTNAARGARGCNATH ACNATGAAYCARMGNTGGCARATGTAYAGYAARGAYMGNGARAARCARATHCARGAYYTN AGYGAYMGNYTNTAYGARYTNTCNGAYCCNAAYCAYGARGCNGCNATGGTNGARGARGCN ACN---------AARCARAARACNGCNCAYYTNACNATGGARYTNAAYAARAARGARGCN GARYTNGTNGARYTNAARMGNAAYAAYATHYTNATHATHGARYTNACNGAYGCNAARAAR TGGCARTCNCARTCNCAYCAR------GAYAGYACNGTNGARATHYTNAARCARCARATH CARGTNTGYACNGARGAYTTYAAYACNGARMGNAARGAYMGNGARAARGCNGTNCARAAR GCNMGNACNYTNCARCARGARAAYGAYMGNYTNAARGARGARMGNGCNYTNATGAARAAR ACNATHGARCARCARCARMGNCARGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AAYAARYTNAARMGNTTYYTNAARCAR GCNGARYTNGAYCAYTAYGCNYTNTAYAGYGCNYTNTCNTAYYTNAARAARTGYGGNTGY GGNACNYTNATHYTNMGNTAYGTNAARYTNGAYGCNGGNCCNGARACNAARTCNGTNYTN ACNGCNYTNGARAAYTTYATHAGYTCNACNMGNCARATHYTN---GGNATHATHTGYCAY GGNTGY---------CARTAYGCNACNTGYGGNGAYAAYTAYAAYATHAAYGARTAYTCN MGN------AAYYTNGGNGAYTGYGGNGAYGGNATGTAYTGYGTNAARTAYAARACNATH ATHTGGATHMGNAAYTCNGGNGARATHACNGGNAAYTCNYTNGARTCNCAYGTNGTNACN MGNAGYTGYGARTCNAARAARGGNCARAARGARGGNTGYATHAGYTGGCARAAYAAYGGN GGNGTNACNATHAARTGYTGGTGYGGNACNGAYGGNTGYAAY------------------ ------------------ATGCAYAAYMGNGGNGGNYTNCCNGTNAARAAYATHGTNACN GCNATHTTYATHYTNYTNTCNATHTAYYTNYTNTAYATHTAYAAYGTNTCNCARAAYMGN YTNCAYGAYGCNGARATGACNGGNTCNMGNTAYMGNMGNGARACNGARGARAARGCNAAY GARATHCARGGNYTNGTNGCNGCNAARGAYGAYTTYCARGARMGNTGYGARGCNGARAAR MGNGARYTNAAYAAYMGNYTNAARTCNATHAAYCARAARCAYAGYATGYTNCARAGYCAR AAYACNGARATHGARGCNGAYTTYATGAARYTNAARCARGAYATGGAYAAYYTNMGNACN GARCAYATGCARACNAARAAYCARCAYGCNGARGARTAYCARACNYTNAARCARACNAAR GARAARGARYTNTCNGARYTNACNGAYCARATGGAYATHATGAARAARCARAAYGARGAR YTNCARAAYACNATHAAYACNYTNCAYGCNGARATHCARAAYTAYGARATGGARYTNCAR AAR--------------------------------------------------------- ------------------GCNYTNCAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CCNACNYTNAAYAAYTCNTCNACNTTY AGYGGNATGACNAAYACNCCNGAYGTNAARCCNAGYAARAARYTNYTNGAYCARYTNATG CAYAARAARTAY---------------------------TCNGGNAARTCNAARGGNAAY YTNTCNGCNAGY---------------CARGARACNTAYGCNTGGAARYTNAARAARYTN AARAARACNATHGARGAYTAYATHTTYGTNAAYGGNGCNGTNTGYGAYGARGTNYTNMGN ACNGARGARAARYTNGCNMGNGTNAARGARGARMGNMGNTTYYTNYTNMGNAARYTNYTN CARTAYCARTCNYTNAAYGARTCNTCNGGNGCNATHGCNAARGCNGAYACNCCNGCNGCN ATGGTNMGNAGYYTNAARGCNGCNGCNGCNYTNGARACNGCNGCNGGNAAYGAYACNCCN GCNAARGGNTCNAARGGNACNAARMGNAARYTNAAYGCNTCNTCNTCNGGNAGYGGNGGN CARGCNGGNGCNGGNGCNAAYATGAAYATHGTNTCNTCNYTNCCNGCNTCNTCNTCNACN TCNGARAARAARAARAARCARCCNCARTCNGCNAARGAYATHYTNGAYTCNYTNCARGGN MGNCCNAARAARAGYAARTCNGCNGGNAARAARACNATHCCNCCNYTNATGYTNGAYTCN YTNGGNMGNCCNATGATHCCNATGATGYTNGARGAYATHACNYTNCAYAGYATGGGNGAR ATHGTNACNGAYMGNAGYAGYTTYCAYTGYCCNGARGCNATHTTYCCNGCNGGNTTYTGY ATHACNMGNGTNTAYGTNAGYYTNCAYAARGTNGAYTCNAARTGYYTNTAYACNTGYAAR ATHTCNGARGGNGARAAYGARCCNYTNTTYGARATHGCNCCNGARGAYAGYTCNGAYATH GTNTTYMGNGCNAGYACNCCNTCNGARTGYCAYAGYYTNYTNYTNMGNGCNGTNAAYAAR TCNMGNGGNGCNGAYGTNGTNTCNACNGARACNCARGGNYTNGAYTTYTTYGGNYTNTCN CAYTCNGTNATHCARAAYYTNATHCARTCNATHCCNGGNGCNMGNAARTGYTCNMGNTAY AARTGGGTNAARTTYGARATHGAYAARACNGARTCNAAYGARAAYTTYAGYATHGGNMGN AAYGAYCCNACNATHAAYTAYGAYGCNTTYATHAARYTNATHACNACNYTNACNCARGCN MGNCCNGGN---YTNGCNTCNCARATGGARAARTCNACNAGYYTNMGNTCNYTNYTNACN AAR---------ATGAAYTTYAAYATHGARYTNGTNYTNGCNTCNGGNGGNMGNYTNGGN MGNGTNACNCARATHGCNCAYGGNMGNACNGTNTCNYTNGARACNCCNATGTGYAGYYTN TTYACNAARGGNGGNAGYGTNCCNTAYYTNAGYYTNAGYATGYTNGARMGNGTNAARCAR GTNCCNGARYTNACNACNATGAGYYTNAAYTCNTTYGTNGARCAYGTNGAYAGYATHMGN GAYAGYGGNAARAARYTNGCNGAYTTYACNTCNATGAARAAYAARYTNATHTTYTCNTCN YTNCAYGAYGCNAGYYTNTCNYTNATGTCNGGNAARAAYGAYAARTCNGGNGTNGCNGTN TGGGGNAARGGNGGNAARACNATGYTNGAYCCNGAYYTNTAYATGAARATHCARGARTCN YTNCARCCNGAYTGGATHATGGCNYTNAGYGAYGGNGAYACNGAYCARGAYAGYACNGAR AARMGNTGYGGNAARGCNGTNGAYMGNACNYTNGAYTTYYTNGAYGARATHGTNTCNGCN CARGARAARAGYGARGTNYTNAARAGYTCNAGYYTNATHGGNGTNGTNGTNGGNGGNTTY AGYGARMGNCAYMGNGARMGNAGYGCNMGNGARACNTCNYTNMGNCCNGTNGAYGGNTTY YTNYTNGARGGNTTYCARAARGGNAAYGCNGARGARAAYYTNYTNGARGAYGARTCNTTY MGNAARATHYTNTCNAARACNYTNAGYCAYYTNCCNGARACNAARYTNMGNATHATHGAR GCNCCNTGGTCNCCNYTNCARGTNATHCARGCNTTYAARCARGGNATHGAYYTNTTYTCN AGYGCNTAYCCNCAYACNYTNGCNGARAARGGNYTNGCNATGACNGARGAYTTYAGYYTN CCNCCNCCNTCNACNCCNACNAARACNGAR---GCNGTNGARAARGARCARTCNGAYACN TCNGGNTCNACNATHGAYYTNAAYAGYAARMGNTTYTTYGARGAYTTYGAYCCNGTNYTN GAYGGNTGYCARTGYTAYACNTGYACNACNTTYTCNMGNTCNTAYGTNCAYCAYYTNYTN AAYACNTCNGARYTNYTNGCNCAYGTNYTNYTNACNATHCAYAAYTTYGARMGNTAYTTY YTNTTYTTYCAYTCNYTNMGNGAYACNATHAARGCNCAYMGNYTNGARGARYTNGARCAR CARYTNYTNAARCAR--------------------------------------------- ---------------------------------------------TGYATHTCNYTNACN CARGCNGCNGCNTTYGTNTGYGCNTCNTGYGTNGTNATHGCNGTNGCNACNYTNTGYYTN TTYCARATHCAYACNMGNATHYTNGAYAARATHYTNCCNTCNTCNAARAARGCNGTNAAR AARAGYGAYGGNGAYAGYCCNCAYGGNGCNYTNGAYACNGTNCARAAYTTYMGNTAYAGY YTNATHGARATGCAYGAYTTYGTNATHAARAGYAAYGARTAYYTNATHCARTTYTAYTCN ATHYTNAARTGGGAYTCNCCNYTNCCNTCNTTYATHTAYCAYACNGARGTNTGYATGTTY YTNATHTGYYTNGTNATGAGYCCNGCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNYTNTAYACNCARCCNATH--------- ---------------------YTNCCNMGNGCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARGTNMGNYTNACNYTNAGYCARTGG AARGCNACNATHTGYYTNCARCARGARGCNAGYCARCARAAYCAYYTNGAYGTNGTNTAY ATHTTYAAYAARATGYTNGARGARCARGCNTTYCAYTTYTGYTAYACNCAYTCNGARATG AAYGARMGNACNYTNAAYCCNGARMGNGARGAYCAYGARATHAAYYTNGCNGAYGAYYTN AARGARGARMGNMGNGARATHAAYMGNYTNTTYGAYTAYGARTCNATGGARCARYTNTCN TAYYTNYTNGAYCAYTAYCAYMGNATGAARATHAAYAAYGCNGGNCCNMGNGCNACNMGN CCNGAYAARTCNYTNGAYGTNGTNCARAGYTCNATGGTNGARGAYYTNGTNYTNATGYTN CARTCNTTYAARGARAGYGTNTCNAAYATHTAYAARCAYGGNTCNGCNAARGTNGTNYTN CCNGARGARGGNCCNTCNGARGTNGGNCARAGYATHYTNAAYAARMGNYTNTCNATHAAR TCNAARATHTAYTCN--------------------------------------------- ------------------------------------------------------------ ATGACNACNGTNTGYGGNTGGYTNAAYTTYTTYTGYYTNMGNGARGTNAAYAARAARAAR GCNGTNCARCAYMGNATHCAYCCNAAYMGNCARCAYTAYGAYGCNGTNGTNGTNTGGAAY GGNAARGARAAYAARAARGCNAARCARGGNAGYATHAGYTTYGAYGTNATHYTNAARCCN GCNGCNACNGAYTCNCCNMGNCCNCCNYTNCCNCAYTCNCCNMGNGAYAAYAARCARAAR GARYTNTCNGARGARAARATHGCNATGAARYTNAARAARGCNGARCARMGNMGNAGYYTN ATHGARCARGARMGNATGGARCARATHGCNAARGARMGNCARAARGCNATGGARGTNATH ACNAARGCNCARTCNGARAGYCARGARTTYTCNAARAARACNGARGARAARYTNMGNMGN TCNATGGARATHMGNMGNGARAAYMGNGARACNCARATHMGNGCNYTNCARGARMGNYTN MGNGARCAYTCNGTNAARGTNCAYGAYGTNCARAARGCNGGNATGGARATGGTNAARGAR TTYGARACNAARGCNGARCARAARYTNACNCARAARATGGARGCNTAYGARGARAAYMGN AAYAGYCARYTNTGYAAYATGYTNGCNAARYTNCARGARCAYGCNAAYCAYATHAAYGAR GTNTGYATHGCNAGYGAYAAYMGNGGNATHAAYACNGAYGARYTNCARGARCARYTNGTN CARAARATGGARAAYGCNYTNAARAAYMGNGARGARCARYTNMGNGGNATHCARGAYMGN YTNGCNGARCAYGARAAYMGNATHAARGARGTNCARAARAARAAR---GTNGTNTCNTCN GGNGAR------------------------------------------------TTYTTY YTNMGNYTNCAYYTNGCNAARCAYGGNGGNTTYAARTAYCARACNACNYTNTCNACNCAR GAYGGNYTNYTNATHTGYTCNCAYTGYAAYTAYATHGCNCAYAGYAAYAGYGAYYTNGTN AAYCAYGTNAGYATHCAYGTNACNGAYMGNMGNTAYACNTGYTCNYTNTGYCARTTYGAR AGYCAYCARAARAARTCNATHGARGCNCAYATHGARAARAARCAYAARGAYGARAAYGAY GCNAARGTNATGGAYMGNGARMGNAGYAARGGNAARAARYTNAARYTNCARGTNGTNAAY YTNAAYCCNACNGTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AAYAGYGCNCARTTYATHGARGTNGARTTY GAYATHGCNGTNMGNYTNTCNAGYATHCAYATHTAYGARACNTAYAAYCCNGGNGCNYTN GTNMGNATHAARGGNMGNGARTCNAGYGGNCCNTGGTCNGTNYTNTGGCARACNGARCAY CCNGTNMGNATGTAYGGNAGYMGNATHTTYTCNCCNACNYTNCCNGAYAARYTNYTNAAR GTNAAYCARATHMGNYTNGARATHGAYTGYAGYGCNGCNCARGAYTGGTGYGARGTNGAY GCNGTNCARATH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GAYGARCCNGCN YTNTCNCARGARCARGGNGAYATHYTNAARTTYYTNATHCAYAARYTNTGYCARAARGAY CCNCAYCARYTNTTYYTNMGNYTNGARTCNCARGTNMGNGARATGGTNATHGARATHAAR ACNGGNYTNYTNCARAARYTNAAYGAYAAYGGNGTNCARAAYCCNGCNYTNGCNYTNGAY TTYACNAGYACNYTNYTNTAYCAYTAYGAYYTNATHACNAARAARGCNCAYYTNYTNGCN CARTAYYTNGGNGGNYTNACNGAYCAYYTNAARCARTTYCARGTNACNTGGGARYTNYTN AAYAARCAYYTNTTYCAYTCNATHGCNCAYAAYGAYCCNGCNATHAGYTCNGTNGGNCCN ACNATHYTNGARCARYTNMGNCARGGNTCNYTNAARTAYGARAARTCNMGNGARGAYCCN TTYTGYAGYGTNMGNAARMGNYTNYTNAARTTYCARGARGARATGTCNGTNGTNGTNGTN GTNTGGMGNGAYTGYCARYTNYTNATHGARAAYTAYTGYCARGARGARTTYACNAAYACN CARAARCARGTNTCNCAYMGNGCNAARAGYTTYATHACNCARCARMGNCARTTYYTNAAR AAYCAYYTNATGAARGAYTCNTTYATGGAYGARGARACNATGAARAGYYTNGTNTCNGGN CAYAARTCNTCNAARGARAARGTNYTNTGYCAYMGNTGYAARMGNGARMGNTGYACNTGY GAYGARTGYACNATHACNCAYATGATHACNTGYGGNATHATHAAYACNGARAARGGNACN ACNYTNCCNCCNCCNCCNAGYTCNTTYAAYTTYGCNYTNGAYCAYACNCAYAAYGTNATG GAYATHACNCCNCCNTCNATGTCNAGYACNACNTCNAGYAGYGGNTCNGTNTCNCCNATH AAYGTNGARGAYAARATHACNGCNTAYGAYTGYGARAARMGNGAYGCNATGYTNACNYTN GAYGAYYTNATHGAYAAYATHGAYGGNAAYGCNGGNGAYGAYGARGAYGARGAYATHGAR GAYACNAAYAAYTGYGTNGAYGARCARAAYGGNAGYGAYGARCCNCAYGCNATGCARTTY CARCCNMGNATHGAYAGYCAYYTNTCNAARCARYTNGAYGCNGARATHGCNAAYTCNGGN GTNCCNTCNAGYACNATHAGYGAYTTYATGTCNTCNGARAGYATHGCNGARGGNYTNACN AGYAGYTCNGGNAAYGTNAAYGCNAAYATHTGYGCNGCNTGYCARTGYCAYGCNTGYYTN AARCARAGYGGNCAYGTNATHTCNACNTCNYTNCCNYTNCARGTNCCNGTNTCNCCNCCN CCNGCNGARYTNAAYYTNTAYCCNCAYATHCAYGGNYTNCCNCCNGARMGNTAYATGTTY GGNYTNCCNTCNCCNYTNYTNCCNTCNATGAARYTNCCNTTYAARYTNGAYTTYGAYGAY CCNGCNAGYATHCAYGAYCAYYTNTAYCAYGCNTAYAGYGAYTGGGAYAAYCCNMGNCCN GGNTCNYTNGCNTCNCARCAYCARCAYCARTCNCAYCCNMGNYTNTCNGGNYTNACNTCN GAYYTNYTNCCNCCNGCNCCNGTNGTNGAYGCNGTNCCNGCNTTYAGYTTYGARGCNYTN AAYYTNTCNACNCAYAGYACNCARACNYTNACNAAYACNAGYAGYGCNTTYAARTCNGTN GCNGGNAARAGY---TGYGARAAYTTYGTNTCNAGYACNAAYAGYTGYAGYACNGARGGN AGYTCNGTNGAYCCNACNACNAARCCNMGNGAYTTYCCNTCNTTYTCNAARATHCCNCAR GCNTGYYTNAAYGCNTCNTCNTCNTCNYTNCCNATGTTYACNCCNTCNGTNCCNTCNGTN GTNCARCCN------GTNACNACNTCNGTNTCNGCNTCNMGNGCNGTN---------AAY GGNTCNTGYCAYGGNCCNCCNTCNTCNMGNCCNGTNCCNYTNGGNGGNAAYGCNGTNTCN AGYAARTGGGARAARACNCAYTCNYTNCARTGYAARAARTTYACNGCNTCNGGNCCNAAY AARTTYGCNYTNYTNAAYCARCARGGNGARCCNGTNAAYCCNTTYTCNCCNGGNMGNTCN TGYACNCCNACNAGYTCNTCNTCNTCNTCNTCNYTNTCNAAYACNCCNTCNTCNYTNCCN ACNTCNTGYCCNAAYGCN------------------------AAYGCNAAYYTNCCNTCN ACNGTNGTNAAYAAYATHGGNGTNGGNACNACNTCNCCNTGYGTNGAYTCNGARTGYAAR GTNCAYCAYGAYGAYAAYTGYGAYAGYGTNGAYGAYAGYTGYTCNGARMGNAGYTCNAGY ACNTCNTCNAAYCARAARGARGGNAARTAYTGYGAYTGYTGYTAYTGYGARTTYTTYGGN CAYAAYAAYCCNCARGGNGCNAARACNAGYCCNAAYTAYTTYGARATGAARGAYMGNYTN MGNAARAARYTNAARAARAARAAYGARACNAARCAYAARTCNGCNCCNCCNCCNGCNGTN GARGGNAARMGNGARGARCAYCARAARACNGCNATGGARAARMGNGGNYTNGAYGARYTN YTNAAYTTYATHAAYGGNACNGAYGARAGY------AAYAAYAARGCNGCNAARMGNGCN MGNCARAARCARMGNAARATGGARGARAARGCNMGNCARGARGGNTCNCARAARTGYCAR GARAAYCAYTGGCARCCNGARGTNACNAARTCNYTNTCNAAYYTNYTNYTNAARCCNCAR ATGGGNYTNATGCARCAYCAR------------------------AARCCNCCNACNACN GAYCARGARMGNATHAARGARYTNCAYAARAARYTNACNMGNYTNAARGARGARATGAAR CAYGARACNACNMGNTCNCCNATGATHATHGARCCNACNMGNCCNYTNATHGTNYTNGAY ATGATHCARCARACNYTNAARAGYACNCARCARAGYCARCAYCCNACNAAYGGNAARAAR TCNCARTCNCCNTCNCCNACNCCNNNNACNAARAARCCNATHGCNGCNACNAARGARCAR CCNYTNCCNCCNCARATHCARAAYMGNGTNCARYTNCARCCNAGYCARATHYTNCARGCN TCNAARTCNTCNMGNAAYCARAARGCNACNGAYATGGTNTCNAAYTCNCCNAAYCAYGTN AARTCNACNACNGCNCARACNGTNTCNGGNGARAARAARGTNGTNTCNTCNAGYGCNTCN AAYGGNGTNGCNTCNTCNAARGCNCCNGCNTCNAAYGGNTCNACNAARGGNTCNGCNACN ACNATHGCNGTNTCNGTNTCNAARGGNGTNTCNTCNTCNGCNGTNAGYTCNACNACNTCN ATHTCNACNACNGTNCCNAGYTGYAARGCNGTNACNATGAGYAAYGGNCARAGYTCNMGN AGYTCNTCNTCNGARTCNCCNTCNTCNMGNGCNAARGCNCCNATHGARCARACNAARGCN TCNAARAAYMGNAARAARAARAAYAARCAYGARAAYGGNGAYGTNCAYGAYCCNGARGAR GTNTTYATGCCNMGNTCNGARTCNGARYTNGAYGGNTCNGTNGAYGAYTTYGARMGNGAR YTNGARGARTTYAARMGNTTYTGYTTYGARACNTCNCAYCCNAARGARAARMGNAARYTN GCNGTNAAYGTNAAYYTNAARGAYATHTTYAARAARAARTCNTGGGGNTCNATGMGNTCN AARCCNACNCARGCNATGCCNAARCAYTCNYTNTTYGGNACNGCNYTNGARAARGTNAAY MGNGARAGYYTNAARGAYATHGARGGNMGNTAYATHCCNGARGGNCCNGTNAARGARATH CCNAAYMGNTAYCCNYTNCCNCCNCAYATHAARGARAARATHCCNGGNCARGAYTAYYTN GARACNTCNMGNAARGARTGGGCNGCNCARMGNGAYGCNYTNYTNCARGCNGAYTCNCAY YTNAARGCNAARTCNGAYAARGTNTTYTCNTTYAARGCNGCNGARGGNAARCCNGGNTCN AGYCAYGGNAGYGTNCAYTCNAGYMGNCCNGCNTGGYTNTCNGARAARGAYATHGARCAY TCNAARGAYATHAAYATHYTNGGNYTNACNCARMGNGGNAGYTAYAAYMGNGAYAARTAY GGNAARAARCCNCARGTNCAYAAYTAYAGYYTNATHGGNGAYATHATGGCNCCNAARATG GAYTTYAAYTCNGCNMGNCCNGGN---------GAYGARGARGARAARACNGGNGCNGCN AAY---ATHGCNYTNGGNCCNGGNMGNCAYYTNCCNTAYGAYYTNATGGAR---AARCAR AAYAAYAARAARAARACNAAYCCNAARAGYGTNGTNGARYTNCCNCCNAAYATHMGNCAY CARTTYGGNAGYMGNGTNTGYGAYACNYTNYTNTCNGAYCARGCNATHGTNACNYTNGCN YTNGARMGNCARAARACNAARATGGGNCCNCCNMGNCCNTCNAARAARGARAAYGTNCAR GGNYTNCCNGTNAAYYTNGARAAYACNTAYGARAGYYTNGGNCAYACNACNMGNTAYAAY GTNTGYCCNGGNGTNAGYTCNGGNCAYAARATHAGYMGNACNAARGAYGARTTYAAYGAY GARGTNCAYYTNMGNMGNGTNCCNAAYACNGAYGARTTYMGNTAYCARMGNGAYGARYTN AGYACN---TGGTCNGARCAYAAYGTNYTNMGNGARMGNATGAARAARGCNTGG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATHGCNATH ATHGGNAAYTCNTGYGTNGTNTAYYTNGTNGCNTCNAARMGNMGNATGMGNAAYATHACN AAYTAYTTYATHGCNAGYYTNGCNGTNAGYGAYATHATGATHGCNGTNATHTGYATHCCN TTYTCNTTYACNGCNAAYGTNYTNTTYACNTAYTGGCCNTAYGGNAGYGGNYTNTGYCCN ATHYTNCAYTAYTTYCARGCNGCNGTNGTN------------------------------ ------------------------------------------------------------ ---------TCNAAYATHCCNAGYATHACNTTYAGYTGYAAYTCNTGYGAYTTYGTNATG GAYTGYCAYTAYAARGGNACNCARCCNCCNTTYGCNAARCARTTYATHYTNCAYGARGAY TGYTTYGTNATGAARGAYCCNTTYTCNACNACNGGNGGNTTYATHAGYGTNGGNGCNGTN TGYTCNCARTGYAARGARAGYGTNTGYATGGCNACNAGYTGYAGYTTYTTYTAYACNCAR MGNTTYTGYATHAARTGYGCNTCNGAYAAYATHATGGARTTYCCNCARGARYTNCAR--- ------------------------------------------------------------ ------------------------------------AAYGGNGGNTTYTGGACNGCNMGN GTNAARTTYAGYCARGAYGTNTGGAGYYTNGARTGYTGGGAYGCNGTNAGYAAYMGNGAR TAYACNYTNACNTTYTGYTTYCAYGAYGGNAGYTCNGGNGGNAARGAYTAYGCNTCNGCN YTNGGNAARTCNGTNYTNTTYTAYGAYGCNCARMGNTCNGGNAARYTNCCNGCNAAYAAY CCNATHTCNTGGMGNGGNGAYTCNGCNYTNGGNGAYTGYGTNGTNGGNGGNTGGTAYGAY GCNGGNGAYCAYGTNAARTTYGGNYTNCCNATGGCNTCNTCNGCNCAYYTNYTNGTNTGG GGNGCNATHAARTTYAARGAYGGNTAYGTNAARGCNGGNCARATGGAYATGATGTAYGAY TCNATHAARTGGGCNYTNGAYTAYTTYTCNAAYGCNTGGAAYGARGGNTCNCARGARYTN GTNGTNCARATHGGNGAYGGNAAYGCNGAYCAYGCNTAYTGGGGNMGNCCNGARGAYATG AAYATGTAYMGNCCNTGYYTNAARATHAAYAGYGGNACNCCNGGNAGYGAYATHGCNGGN GARACNGCNGCNGCNATGGCNGCNGGNTCNATHYTNTTYAARGAYAARGAYCCNGGNTTY TCNGGNAARYTNYTNAAYAARGCNAARAGYYTNTAYGCNTTYGCNAARGCNCAYMGNGGN GTNTTYCAYGGNAGYGCNCCNTTYTAYGGNTCNTCNGGNGAYAARGAYGARATGTGYGAY GGNGGNGTNTGGYTNTAYMGNGCNACNAARGAYAGYCARTAYYTNAAYGAYGCNAARGCN AAYGCNGAYACNGGNACNGCNTGGTCNYTNAGYTGGGAYGAYAARMGNGTNGCNTGYCAR GCNYTNYTNTAYGARGARACNAARGAYGGNTCNTAYAARGGNGCNYTNGARGCNTTYTTY AAYTCNTGGYTNCCNGGNGGNGGNATHACNTAYACNCCNTGYGGNYTNGCNTGGMGNGAY AARTGGGGNGCNAAYMGNTAYGCNGGNAAYAGYGCNTTYGCNGCNYTNGTNGCNGCNGAR GAYGGNATHATGGCNGAYAARYTNMGNCCNTGGGCNGTNCARCARATHAAYTAYYTNYTN GGNGAYAAYMGNCAYGAYGGNGGNTGYTTYAGYTTYGARATHGGNTAYGGNTCNAARTTY CCNMGNCAYCCNCAYCAYMGNGGNGCNTCNGTNAGYGGNCARATHYTNCARGGNGCNYTN GTNGGNGGNCCNGAYGCNAAYGAYAAYTAYAAYGAYAGYCARGAYGAYTAYGTNATGAAY GARGTNGCNACNGAYTAYAAYTCNGGNTTYCARGGNGCNYTNGCNGGNATHGTNTCNYTN GARGCNGCNGGNAARTTYCCNTCNACNTCNAAYAARTGYCCNTGY--------------- ---------------------------------------------MGNTTYTGGGCNACN ATHTCNGCNTCNGTNMGNCAYGTNTTYGARCARMGNGAYCCNTGYTAYCCNAGYGTNATH YTNATGACNTCNCARAAYAARAAYAARMGNYTNAAYACNTGYYTNGCNAARAARATHGCN TCNATHTTYTCNTCNTCNCAYGGNYTNGAYTCNCARAGYTCNMGNATHGAYGTNGARGAY ATHAARCAYYTNGARTCNGGNCARCARAARYTNACNYTNGAYGARGCNATGCARACNGCN TTYCARCARAAYAARGARAARGCNTTYGTNATHAGYAAYATHCAYTCNYTNTCNCCNACN GCNGCNYTNYTNYTNCAYGGNTTYTGYGAYGGNGAYAAYGCNCCNTAYAARGAYGTNATG ATHGTNYTNACNTTYCARGTNGAYGAYAGYATHATHTTYCAYTCNGTN---------AAR GARGTNGARGGNTTYYTNACNGAYTTYTGGAGYCARGGNYTNCAYATGGAYAARYTNTCN GCNYTNATGAGYMGNATHGCNAAYAAYCCNGTNGTNYTNAARGCNGARGGNGARAAYATH GTNAAYAARTTYTGYATGGCNACNCARACNGARAARTGGYTNTGYMGNGARYTNGGNAAR TTYGGNATHGAYTCNAAYGARGAYAGYGCNMGNTAYATHYTNTCNATGGARAAYTCNAAY GAYYTNGARGARTAYATGYTNGARYTNYTNGAYGARAARAAYCCNAARGTNMGNTTYTTY YTNCARGARYTNAARGAYMGNYTNTGYGCNAARGGNCARAARGGNAGYGTNCARGTNTAY MGNAARGARAARGCNTCNGARTCNTGGGARGARAARTCNAARAARAARAAYACNAARTCN ACNAAYAGYAAYAAYGCNACNAAYAARCCNATHTCNAAYGGNAAY---------GTNCCN GARAARTCNYTNGGNYTNAARGCNGARAARGTNCCNAGYAAYMGNGTNTCNCCNCARAAR TCNGGNGARATHGGNGTNGGNGCNAARAARAARTCNAARTAYGTNCCNYTNTAYAGYAAR GARGGNCARGARAARGCNGTNGTNCARYTNTCNGGNMGNCAYAARTGYGAYTGYCARGCN TCNAARCAYAARYTNATHAAYAAYTGYACNCARTGYGGNMGNGTNGTNTGYGCNCARGAR GGNGCNGGNCCNTGYATHTTYTGYGGNGCNYTNGTNTGYTCNCCNGARGARATGGARATH YTNGGNMGNGGNTCNMGNAARGCNGARMGNYTNMGNGARCARYTNATGMGN---GARGCN TCNAARGGNYTNAGYGARACNAGYCARTCNYTNYTNCCNATHGGNTTYACN------AAY CARTCNAARGARGARGARGARAARGCNYTNMGNCAYMGNGAYAARYTNYTNGAYTAYGAY MGNACNAGYGTNMGNMGNACNCARGTNATHGAYGAYGARTGYGAYTAYTAYGCNACNGAY TCNAAYMGNTGGYTNAARAARGARGAYMGNGAYAARYTNMGNAARMGNGARGARGARYTN MGNGAYTCNMGNCAYGGNTCNMGNMGNGAYMGNAARATHACNTTYGAYATHGCNGGNMGN AGYGTNMGNGTNYTNGAYGCNGARGARGAYACNAGYAARACNATGTAYAGYATGGARGAY ACNGTNATHCARGARGTNCAYTAYGGNAARTCNGCNTCNAAYGGNAAYGAYCCN---AGY YTNGTNAAYCCNYTNTTYGAYTTYGARCCNCCNACNTTYYTNGAYACNGARCCNGTNCAR TGGGGNCCNGAYACNTTYAARCCNGCNTCNGCNAAYCAYYTNAAYCCNCARATHTCNTCN MGNMGNATHCARGAYMGNGARYTNCARGARATGAGYGAYGARGGNATGTGYATGAGYATG CAYCARCCNTGGGCNTCNYTNYTNATGTGYGGNATHAARATGCAYGARGGNMGNACNTGG TAYACNGCNCAYMGNGGNMGNYTNTGGATHGCNGCNACNGCNAARGCNCCNGAYAARGAR GARATHYTNGARYTNGARCARTTYTAYAARCAYTAYTAYGGNGAYTCNAARYTNAGYTTY CCNAARGAYTAYCCNACNGGNTGYYTNYTNGGNTGYGTNAAYGTNGAYGAYTGYYTNGGN CARGGNCCNTAYMGNGARAARTTYCCNAAYGGNGARTCNMGNTCNCCNTAYGTNTTYGTN TGYTCNAAYCCNTCNAAYYTNATHGTNAARTTYCCNATHAARGGNAARCAYAARATHTAY AARYTNGAYTCNCAYATHCAYCARGCNGCNAARAARGGNATHMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GARGARATHGTNMGNTGYATGGGNACNMGN GARYTNGAYTAYGTNGAYAAYYTNATHAAYGGNCAYATHGAYTAYYTNGTNMGNYTNCCN MGNAGYYTNYTNYTNAARYTNGTNATHTAYYTNGAYYTNGTNTCNATHYTNAARYTNGGN CARGTNAAYAARCARTTYCARGARYTNTGYTCNTGYAAYGARYTNTGGATHAARGTNTAY AARMGNCAYTGYAARAARCARGTNTCNCARGARYTNYTNATGGTNGCNGAYNNNAARGGN TGGAARGARGTNTTYTTYATGAAYAARYTNCARYTNCARGTNCARATHMGNMGNCAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AAYTCNGAYGCNACNGCNACNAGYAARYTNACNGTNATHGTN AARGGNAAYTCNATGTGYACNTCNAARAAYTTYCARACNTAYCARGCNCARACNAAYATH YTNCCNGGNGCNTTYGARGAYGGNCAYGTNACNTAYGGNCCNTAYMGNAGYYTNGARYTN ATHGARGTNGAYCCNGGNAARCAYGTNGARATHCAYATHMGNTAYATHGARACNATHGTN GTNATHMGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGGCNTCNCCNGTNTAYYTNTGGTTYACNAARGARGTNTTYTAYTGGMGN AGYYTNGCNGCNACNYTNTGGGCNGTNATHTGYYTNCCNGTNYTNATHTTYYTNATGTCN YTNATHYTNAAYATHTCNYTNACNCAYCCNYTNGTNTGGTTYTCNGAYGCNGTNGCNAAY ATGATHTCNGTNCAYTTYYTNGTNACNYTNYTNACNTTYATHGTNGCNGTNGTNACNGTN ACNTGGTTYTCNYTNCCNTAYATHACNGTNAARCCNGARATHTGYAGYTCNMGNYTNTTY GGNGTNYTNGGNYTNTTYMGNTGGTCNMGNYTNCCNYTNYTNGTNGTNTGYYTNYTNAAY GGNGCNYTNTGYGCNTGGAGYGTNGCNAAYYTNGCNGGNTCN---CAYTTYACNGAYTTY GTNAGYACNCARGARTAYGARAARACNGTNYTNAAYGARAGYTGYATGTTYATHGTNGGN TGYGGNATHTTYACNGGNTTYTGYTAYTAYTGGCARTTYTTYACNCARCARGARTCNTTY YTNACNTTYCCNAGYATHCARMGNCARAARGTNTTYCARGTNMGNAGYGARACNMGNATH ATGGCNGARAARATHTCNTGGAARACNYTNCAYGTNATHAARTAYTAYTAYATHGCNTAY TTYYTNTTYGGNTCNYTNCCNMGNATHTGGGTNTGYTCNTCNTTYGGNATHAGYGARGAY AAYGARTCNGCNCCNYTNGAYTCNATHGTNGGNYTNACNAGYYTNTCNYTNYTNTGGAAR TCNTAYYTNACNTCNTTYGTNYTNACNTTYGCNYTNTCNTTYACNATGGCNYTNACNMGN ATHTTYCAYACNGARCAYGTNGARTTYCCNGTNACNAGYATHATGGARTAYTCNAAYGAR MGNACNYTNTCNGAYGCNYTNGCNTGYTCNTAYTCNCCNYTNYTNCARCAYYTNGCNTTY TAYGAYYTNGCNTGYTTYAGYAARTTYGCNTCNCCNMGNYTNCARGARYTNYTNAGYYTN ACNCARCCNGGNGGNCAYCCNAARATHTGGATGYTNGTNTGYGGNTCNGCNYTNTCNGCN ATHCARGARYTNACNAAYCARGTNAARGARGAYAAYTGGTCNATHYTNTCNAARGTNCCN ATH---------AAYCAYCAYMGNAAYGGNGTNCCNAAYGGNAAYGGNTAYGTNYTNAAY GGNGCNGCNGARGAYMGNATGAGYTCNTCNYTNATGTAYMGNGGNGARGTNAAYCARGAR GARYTNGARAARCCNAGYYTNATHTCNCARYTNAGYAAYMGNYTNTCNTCNGTNCCNATH YTNTCNCAYYTNGTNACNCARAGYCARGARTGYAAYAGYMGNMGNYTNTTYGCNGCNTCN CARGTNCARATHTGGGCNGTNGARAGYYTNTCNCAYATHACNGTNMGNGCNTAYACNGAR GAYAARTAYGGNGTNGTNCARACNTCNYTNCCNATHATHTTYATGTCNYTNYTNGARYTN CAYGARTCNATGGARAARCAYTTYAARYTNAGYACNTCNCCNMGNMGNACNAAYGGNTCN ATHAAYCCNTCNGCNGAYTGYGTNATHMGNTAYAARYTNCAYTCNGTNYTNAARTCNTCN YTNTAYMGNATGGTNAAYACNTAYAARGCNCAYYTNGARGAYATHAARYTNAARCCNGAR GARATGAARMGNYTNATGCCNTTYGCNCAYTAYACNYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TTYTCNYTNGTNTTYTTYYTNTAYAGYMGNGARGAR AGYGAYAARAARGCNYTNAAYTAYGTNTTYTTYGGNYTNTTYYTNGTNCAYACNATHCAY MGNGGNATHATHCAYCCNTTYATHATGAARTAYAARAGYAAYAARGTNCCNATHGGNATH TGYATHGGNGGNGCNYTNCCNAAYGTNYTNTAYCARTGGYTNATHGCNAAYCAYATHGGN GTNGCNAARTAYGAYGAYTCNTAYCCNTAYGAYCCNMGNTTYATHYTNGGNGTNYTNYTN TAYGTNGTNGGNTTYATHATHAAYMGNTGGGCNGAYTGGAARYTNMGNTCNYTNMGNAAR MGNAARGGNGCNYTNGARGGNGAYGAYAGYAARGGNTAYTAYATHGCNTAYGGNGGNYTN TTYAAYTTYGTNTCNTGYCCNAAYTAYTTYGGNGARYTNGTNCARTGGATHGGNTGGACN ATHTCNACNTGGTCNYTNTCNGGNTTYGTNTGGACNYTNTTYTCNGCNGCNACNTTYTTY GCNMGNTCNMGNCAYAAYCAYAARTGGTAYCARGAYCAYTTYGARGAYTAYCCNTCNGAY MGNATGGCNYTNATHCCNTTYGTNTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATHCARACNMGN TTYGCNTCNTTYGGNACNAARYTNGTNCCNAAYMGNAARATGYTNYTNGGNGGNTCNACN ATHYTNMGNTAYGGNMGNAGY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CCNGARGCNTCNTCNGAYGCNACN GTNTAYATHAGYYTNAARGGNGAYGARGAYGTNYTNYTNCCNACNCARYTNAGYMGNGGN CAYTCNAARMGNAARATHTTYTTYGCNCCNGGNTCNAARGARACNTTYTTYATHAARGGN CCNCARYTNGGNAAYYTNGARATHYTNTCNATHGARCAYGAYGGNATGGARAARAARCAY GGNTGGTAYTGYGAYAARGTNGARATHACN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TCNTGYGTNAAYMGN GTNGAYATHGGNGGNATGACNTAYATHMGNACNGGNCCNGAYACNYTNGARYTNTCNCCN CARGGNAAYAARAARYTNGCNGCNAGYMGNGCNATHCAYAARAGYYTNTAYATHATGGCN TCNMGNCARMGNAARAAYAAYAARAAYAARAARCCNAARAAYMGNCAYTGYYTNTTYTTY CAYMGNTTYGGNAARTGYCARCAYGGNAAYGCNTGYCCNTTYATHCAYGAYYTNGARAAR GTNGCNGTNTGYTCNMGNTTYYTNMGNGGNCARTGYGARACNYTNAGYTGYCCNTTYTCN CAYGAYGCNTCNGTNCAYAARATGCCNGTNTGYYTNTTYTAYYTNCARGGNYTNTGYTCN MGNCARGAYTGYYTNTAYYTNCAYGTNAARGTNAGYCCNGAYGCNCCNGTNTGYAARGAY TTYYTNCARGGNTTYTGYCCNYTNGGNYTNAARTGYAARAAYYTNCAYTCNTTY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGGCNGARAARTTYCARCARATHYTNAARMGNACNATHTGYTTYGGN CCNATGTCNTTYTGYTTYYTNYTNGCNAARGARACNGGNATGTTYAAYACNYTNATHAAY TCNGARAARCCNYTNACNTCNGARGARATHGCNAARGARAAYAARYTNAARGARMGNTAY GCNMGNGARATHYTNGGNTGYYTNTGYGCNGCNGARYTNGTNMGNGTNTCNACNAAYGAY GAYGGNACNTCNGTNTAYGAYYTNGARGCNCCNATHAARGARGCNYTNCCNAAYGCNATG CCN------GARATGAAYTTYGTNAARATHYTNATGAAYMGNTAYGARTCNATHAARGGN GTNATHGGNGARGAYCARCCNGGNATGYTNMGNTAYGAYAARCCNTTYTAYGAYYTNTGG GAYGARTAYAARAARAARYTNACNGAYGGNACNATHGAYTGYATGATGAARAAYGTNCCN GGNYTNAARGARAARYTNGARAARGGNATHGARGTNGTNGARTTYGGNTGYGGNAAYGGN TAYGAYYTNTCNGTNYTNGCNTCNATGTTYCCNAAYAGYACNTTYACNGCNACNGARGTN MGNCCNCAYYTNATHGAYGAYATHAARGAYAAYTAYAARCAYYTNCCNAAYATGAARTTY GAYGTNATGGAYYTNATGGCNYTNCCNGAR---------CARAARTTYGAYTGGYTNATH ACNAAYGAYGTNATHCAYGAYYTNCCNTCNCCNYTNGARGGNYTNAARGGNGTNMGNMGN ATGYTNMGNGARCCNGAYGGNGTNTTYACNTTYGTNGAYGTNGCNGGNACNGGNAGYCAY CARAARGAYGCNGGNGAYYTNCARGCNGGNYTNTGYTAYGCNATGGCNACNTTYYTNTGY ATHCCNGARAGYTTYCARMGNGARAAYTCNGARGCNCAYGGNGCNTCNTGGGGNAARGAY ACNGCNYTNMGNTTYGCNAARGARGCNGGNTTYGAYACNAARTTYGTNMGNATGTTYGGN AARGTNGCNYTNTTYATHTGYGAYGAYCCNGARAAYCCNCCNTCNTAYACNGARMGNAGY AAYGTNGCNACNGGNCCNGGNGTNAAYCCNCCNGAYTAYAAYACNGCNTCNTTYCARGAR CCNCCNCCNACNTAYGAYTCNATHTAYGGNMGNGTNAARGCNGCNAARGCNCARTCNCAR GGNAAYGTNGAYTTYTTYAARACNTTYATHATHATHATHYTNTCNACNATHGGNTTYACN ATHATGYTNGCNGTNTTYATGGCNGTNCCNGTNTCNATGATHGTNATGGGNGCNATHTAY YTNGAYGAYTGYGAYGCNGARMGNATGATHCCNATHTAYYTNATHGTNGCNGGNAGYTTY GGNTGYGCNAARAAYYTNTTYAGYYTNATHCARMGNTGYMGNAARAGYGARGARGARMGN CARGARGAYCARAARAARGTNAAYCCNGTNGARGGNATHGTNAAYTGYTTYATHTTYGCN TGGTTYATHGCNGGNTGYGTNTTYATHTAYMGNACN---AARGAYGARTTYCARTCNCAY ACNAARGAYAARGCNAAYTAYTGYGAYTAYACNYTNTAYTGGTAYGCNTTYTGGATHACN ACNTCNGTNTAYATHYTNATGGCNGCNAGYTGYYTNTGYGTNTGYTGYATHGGNTGYYTN GCNTCNTGYTTYGTNAARAAR---------------------------------GARAAR TTYTTYGGNGCNTGYGTNACNGGNAARTGGATHGTNACNCCNGARTTYATHATHGAYAGY TAYGARGTNGGNATGTGGYTNGARGARGARAAYTAYYTNTTYMGNGTNAARGAYTCNATH AARGAYCARYTNGCNAARGCNGCNCARMGNTGGMGNAAYCAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNGGNTCNAGYGGNCCNYTNMGNTCNGAYCAR YTNGCNAARYTNMGNMGNGARYTNGARGTNGTNCARGGNAAYGTNMGNATHATGGGNGAR ATGYTNACNGARYTNAGYCCNACNAGYATHGAYTCNTCNGAYYTNGARYTNYTNCARGAR YTNAAYMGNACNTGYMGNCARATGCARTCNMGNATHGTNGARYTNYTNAAYGARACNGCN ACNGARGARGTNACNGAYGAYYTNYTNMGNGTNAAYGAYGAYYTNAAYAAYGTNTTYYTN MGNTAYGARMGNTTYGARMGNTAYMGNACNGGNCARTCNGGNCARGCNACNACNCCNGTN GCNGARCCNGCNCARCAYGAYTCNYTNCCNCCNTCNTAYGAYCARYTNTCNGCNGCNAAY AAYCCNAARGTNGGNAAYYTNATHGAYYTNAGYGAYGARCCNGCNCCNAGYGAYAAYGCN ATHAAYGCNCARYTNGCNGGNYTNACNYTNAAYTCNACNACNGCNATHAAYGCNGGNCCN CCNGCNCCN---AARGGNGAYGAYGAYTTYGAYATGTTYGCNCARTCNMGNCARTCNTTY GAYCARAAYMGNCARGCNGTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARGTNYTNATHGTNGAYYTNGAYGCNCAYCARGGNAAYGGN CAYGCNMGNGAYTTYATGGGNGAYGARMGNGTNTTYATHYTNGAYGTNTAYAAYMGNGAY ATHTAYCCNCAYGAYGGNTTYGCNAARMGNGCNATHAARMGNAARGTNGARYTNMGNTCN TTYACNCARACNGAYGARTAYYTNGARYTNGTNMGNMGNCAYGTNGARGGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNGTNGGNMGNGAYTTYYTNAGYATGAARGAYYTNAARGCNGAYGAR ATHAARCARATHYTNTGGACNGCNAARGAYYTNAARACNMGNATHAARAAYAAYGGNGAR GTNTTYYTNCCNYTNAARGGNAARACNGCNGCNYTNATHTTYCAYAARACNAGYATGMGN ACNMGNGTNTCNACNGARYTNGGNYTNGCNMGNYTNGGNGGNCAYGCNGCNTTYYTNGGN CCNGARCAYTTYCARYTNGGNGGNAAYGARATHACNCARGAYACNGCNMGNGTNYTNGCN GGNATGGCNGAYATHATHYTNGCNTGYGTNACNGARCARCARGTNYTNAAYACNYTNGCN GAYGARGCNATHATHCCNGTNATHAGYGGNATGTCNGAYYTNYTNCAYCCNYTNCARACN YTNGCNGAYTTYATGACNATHCARGARCAYTTYGGNTAYYTNMGNGGNAAYAARATHGCN TGGGTNGGNGAYGGNAAYAGYGTNYTNCAYTCNYTNATGCAYGGNTGYGCNAARYTNGGN ATHGAYYTNAGYGTNGCNACNCCNGTNGGNCAYGARCCNGARGCNGARATHATGATHGAR ACNYTNAARYTNTCNMGNAARACNGGNGCNTCNTTYCARATGGGNTCNAAYYTNYTNGAR GCNGTNCAYTTYGCNGAYGTNATHATHACNGAYACNTGGYTNMGNGCNGGN---GARGGN GARGGNAARGARAARMGNYTNGCNGAYTTYCARGGNTAYCARGTNAAYMGNAARATHYTN AARGAYGCNGGNGCNAAYTGGGTNTTYYTNCAYTGYYTNCCNMGNAARATGGARGARGTN ACNGAYGAYGTNTTYTAYGGNGARGARTCNYTNGTNTGGCARCARGCNGARAAYMGNATG TGGACNGTNATGGCNGTNATGYTNCARYTNYTNCARGCNTAYACNCCNACNATHTCNATG CCNAARTAYGTNMGNGGN------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNACNGAYATHGGNGAYGAYGAYGAY GAYATGAARGAYTGYGAYGAYATHAARTCNAARAGYYTNGGNGGNGAYGCNGGNMGNMGN GARCAYACNYTNGTNATGMGNYTNACNAAYAARGARCARGARYTNCARGARTGYATGAAY CARATHCARGARATGAARCAR---------------------------------CARCAR ACNCARAAYACNACNYTNGAY------CCNGCNATHAAYYTNGTNTTYCARMGNATGTCN AARGARATGGARGARCAYAARGARAARYTNAARCARAARCAYAAYGARYTNAAY------ ------------------------------------------------GCNTGGAARTTY ACNGCNGAYAGYCARACNGGNATGMGNYTNATGGGNAARTGYMGNATGYTNYTNCARGAR AAYGARGARYTNGGNAARATGATHGCNTCNGGNMGNACNGCNMGNYTNGARGGNGARATH GCNYTNCAYAARGCNYTNGTNGCNGARATGAARAARAAYCARAARGARYTNGAYGARTTY GTNGGNGARYTNGARGARGAYGTNGARGGNATGCARGGNATGATHTTYATGYTNCARCAR CARYTNAARGARTCNMGNGARCARATHTCNMGNYTNCARCARGARAAYGARCARYTNMGN ACNYTNCARYTNCCNTCNGARCCNGARACNGGNAGYGTNTTYAARAAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARGGNMGNYTNACNAARTCNGCNAARAARMGNGGNATG TCNAAYTAYTAYACNATGGGNGAYGARGARMGNGGNYTNGARAARGARTAYTTYGARCCN GTNAARAAYGTNCARGARATHTAYATHAARGCNMGNATGACNGAYGAYGARGARGAYCCN GARACNCCNGCNAGYAGYMGNCCNACNTCNGCNTGY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNACNTCN ATHYTNMGNACNYTNGGNAARTGYGAYTAYCARMGNGAYYTNGTNTCNATHMGNAAYYTN GTNTAYGARATHYTNACNYTNTCNACNAAYGGNTCNAAYATHAARTCNTCNYTNCCNGTN GTNGTNAARTTYYTNGCNCAYCCNGAYGCNTTYGTNAARMGNGTNGCNGGNGARATHATH TCNATHCAYGCNGARGARAAYCARGAYATHACNYTNATGGGNATHAAYACNYTNGTNCAR GAYTGYAARGAYGTNAAYCCNGTNGTNMGNGGNATHAGYTTYMGNATHYTNGGNTCNYTN AARACNATHGCNGTNTCNGARGTNYTNAAYGCNTCNATHATHMGNGGNTTYGCNGAYAAR AAYGGNTAYGTNMGNAARAARACNAARGAYCARATGTTYGAYAAYYTNAAYGARYTNGAY GAYAAYYTNACNAARTCNCAYTGYTTYGCNATGGTNTAYTCNGCNTAYGARYTNTTYTCN CAYTTYACNCARGAYGTNCCNMGNGTNAARAARCARYTNATHGCNTCNGCNTGGTCNTCN ATHAARACNAAYYTNGCNMGNGARMGNAGYGARGARATHATHTCNGCNGCNATHCAYTAY YTNAAYTGYGTNAAYTTYGAYGTNGARAAYTGYTCNGGNGAYAARTTYGTNTGYMGNGAY GAYGAYAGYYTNTAYYTNACNCAYCAYAARATHAGYYTNYTNACNAARATGATHTCNTCN GARAAYGCNGAYAARATHTTYTCNGARTAYYTNTCNTGYGTNMGNACNATGAGYYTNAGY AGYATHAARCAYYTNATGAARACNYTNTCNATHATHYTNATHGARAARCCNGAYGTNTGY AARGCNTGYGTNGAYTTYYTNMGNAAYYTNATHGCNACNGARMGNTCNGARATHATHAGY GARGTNATHCARATHYTNCCNTCNATHACNYTNAGYGAYGCNGARCARTGGAARGARYTN YTNAAYYTNYTNGARGARAARCAYCAYMGNGTNACNTCNYTNGARGCNAARACNGCNATG GCNTCNGCNTCNTCNTGGGARGTNGTNGGNAARCAYAARAARAAYAARGGNGAYTCNCAY AAYATGTCNCCNGCNAARGARAARGARYTNYTNGAYAAYATGCCNAARATHGGNAAYAGY GAYCCNGTNCCNYTNGAYGARACNGTNTAYTCNATHTTYYTNGARAARCARAARGCNTCN CARGGNAAYGCNGCNAGYGCNAARGTNAGYAAYAARCARAAYGGN---AARAARAAYGCN AAYYTNAARAARAARAARGAYGARCAY------AARAARAARCCNAARGCNGTNGAYYTN GARGCNGCNYTNTCNTCNYTNGAYTCNMGNGARYTNCARGGNATHYTNAGYCARTCNCAR GCNTCNTTYCCNAAYCAYCCNGTNATHTGGYTNAARGAYYTNGCNTCNCAYYTNAAYATH AARYTNGARAAYACNAAYGAYATHGAYCCNGTNTAYAARGGNAARTCNACNGGNTTYCCN YTNGAYGCNGTNACNACNGCNTAYGCNACNGTNYTNCAYACNTTYATGAARCARTTYTCN AARCARACNYTNGAYGGNATHTAYTAYTAYGGNATHCARACNATGYTNCARGARTCNGCN MGNGGNATHCCNGTNCAYGGNTAYAARYTNTTYYTNCARYTNYTNTCNCAYACNAARCCN GAYATHGTNATHGAYAARYTNCCNCARTAYYTNGARYTNYTNAARATGCAYCARAAYAAY CCNTCNAARTGYYTNTCNGTNYTNTGGGCNYTNGGNCAYTGYGGNTTYAARAAYTTYAAY TGYGGNYTNAARGTNTGGYTNGARYTNATGYTNCCNGCNYTNGARGTNMGNCARGTNGCN CAYTAYCCNGTNGAYTAYYTNGARGCNYTNATHAARTCNAAYAARAARATGAAR---AAR ------------AGYTTYGGNYTNGTNACNYTNMGNGARTAYTTYCARGTNYTNGAYGTN TTYTTYAGYCCNAARTTYACNYTNGCNAAYGARYTNAARAAYMGNYTNACNGTNYTNTAY CCNACNATHAARACNYTNGCNTAYGGNGAYGTNCCNTCNCARAAYYTNMGNATHTTYTTY CCNTCNTAYYTNACNMGNTTYTCNCCNACNAAYTCNAARGCNATGAARAAYGARYTNYTN GARTGYYTNACNGAYTGYYTNATHACNGAYAARCARTCNTTYAGYGTNTGGTGYCARYTN TAYACNAARCAYYTNTCNGCNTCNAGYCAYYTNYTNGAYCAYATHAAYTGYGARTGGCCN AARYTNTCNTCNMGNYTNGAYAARAARATHYTNACNGARACNYTNMGNTCNTTYATGGTN ACNAAYGAYGARYTNGARATHCARACNAARGGNAARCARGAYAGYYTNAARYTNTGYCAR GCNGCNACNAARGARYTNATGYTNAARYTNACNGGNACNCAYTTYCCNTGGAGYYTNYTN GTNTTYTTYYTNGTNTCNGTNTTYGCNGCNATHGTNGTNTAYGAYATHGCNTCNAGYCCN ACNTTYMGNTCNTCNAARTCNATGCARTTYYTNGARCAYTAYGGNATHYTNGCNYTNYTN GARAARACNTAYCARTGYGTNAAYAAYGTNATHACNYTNTCNATHAAYTGGYTNAARAAR AAYTTYCCNATHTTYTAYAAYTCNGTNMGNGAYACNGTNGTNCCNTTYTCNGTNGCNGTN TGGAAYGGNTCNMGNGAYTTYYTNATHAAYGCNGARGTNCAYTCNMGNCCNTAYMGNGCN YTNGCNATGGARAARGTNATHCARTTYTAYCAYTGGGTNTAYGARYTNTCNCCNGARTTY TGGATHMGNTGYGARGARYTNACNTGGYTNACNTGGGAYYTNYTNAARGAYTAYACNTTY MGNATHTGGAARCAYACNGTNCAYTAYGCNGGNGARGCNGARCAYTGGYTNACNGARCAY GTNYTNACNGGNTCNYTNTCNAARAARGCNATHACNGAYACNGCNATGTGGGGNGTNGAR CAYYTNCARAAYTGYACNTCNYTNYTNGTNTCNTGG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYAARATHGTNYTNGCNAAYAARACNGTNYTN GAYAARCCNTCNATHGTNTTYGGNGCNATHAAYGCNTCNACNATHCAYGCNGARAARACN GARAGYTTYYTNAARGGNAARACNYTNGAYAARGARGTNGTNAARGARGCNTCNCARATH YTNAARGGNGARYTNAAYCCNGAYGCNGAYCARYTNYTNGCNGCNCCNAARTAYMGNMGN GAYGAYAARCCNGTNMGNGTNGCNTAYAGYYTNTCNAAYGTNATGACNACNGGNGGNAAR MGNCCNCCNYTNYTNGCNAARTAYAARGCNGCNATHGAYGGNGGNGGNAARGTNCARGCN ATHGARYTNGARTAYTAYYTNGAYGTNGGNGAYATGGGNGGNMGNAARGTNTTYGAYCAR AARMGNTGGAAYTGYATHAGYMGNCCNCARTAYMGNACNTCNTGYGGNATHTCNTCNGTN GTNTCNTGYTGGAAYTTYYTNTTYTCNACNYTNGGNCAYGGNCAYYTNCAYCCNYTNAGY CARGARGAYGCNATGACNATHYTNGGNTTYGARGCNCCNTTYAAYGAYATHAARTTYGGN CCNTTYACNGGNAAYYTNACNYTNATGMGNTGGTTYMGNCARYTNAAYAGYCAYTTYAAR GTNTTYGGNAARAGYTAYTAYATGTAYAARCCNTGYGGNMGNAAYAARACNATGGGNGTN ACNTCNAGYAARGCNYTNGAYAAYYTNAARATHGGNYTNMGNGAYAARCAYACNGCNTTY ATHTAYCAYTGYCAYAAYCAYTAYTTYTGYCCNGTNGGNTTYGARGARTCNCCNYTNTAY CCNGTNGARGCNTAYAAYGARAARYTNTCNGCNGARTCNGTNGARAARACNTGGGTNYTN ATHGGNGARACNAGYMGNAARTAYGGNCCNYTNCAYTGYAARAGYTGGGARGARATHTGY YTNGAYYTNAARTGYGARAGYCCNGAYTAYTAYAAYATHMGNCARTCNTGGAAYGGNGTN ATGACNCAYCARAAYAGYAARMGNAARGGNGGNACNYTNCAYTGYATHATGTGYTTYCAR ACNTTYGARACNAAYMGNCAYTAYCAYTTYTCNAAYAAYTCNAAYAGYCCNMGNCCNTTY YTNCAYCCNCARTCNTCNTAYAAYCCNATGGCNGAYAAYATHGARTCNYTNTCNCARCAY YTNMGNGARGCNGARAARMGNYTNAARGARTTYGGNAGYGTNATHTCNACNGTNACNAAY CAYGGNCCNCARGAYGARGTNATHGAYCARATGAARYTNATHGARAAYGARATHGARAAR TCNYTNAARAGYCARGARAAYGTNACNTTYAGYAAYAARAARGCNGTNCARGARYTNGAR GCNGARAARGAYGCNGTNTCNTTYAARATHATHTCNCAYAARAARAGYATHAARYTNYTN GAYGAYGARYTNAGYCAYYTNYTNAARGARAARGTNCARYTNAAYGAYGTNCCNGAYAGY GAYATHAAR---GARGTNAARACNAARCARYTNGARACNGARGAYYTNATGTTYMGNAAR CAYYTNGGNATGGARATHMGNAARGTNAARGGNGGNTGYYTNCARGTNGCNTTYAGYCAR ATHGAYCAYAARCARCCNAAYTCNYTNTTYYTNTTYTCNYTNAARTTYGAYGARAAYMGN CAYTAYATHGTNTCNGAYTGYAARCCNCCNATHTCNTAYYTNGAYAAYATHGTNCAYAAR YTNAAYACNGAYAAYAAYTTYCARAARTTYATHCAYACNATGMGNAARMGNTTY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNAARMGNMGNTAYAGYGAYGTNYTNGAR---GAYCCNTAYAARGGNCCNCCNGAR TTYATGGARGCNGGNGTNMGNGGNTTYYTNGTNACNTCNATHCCNGAYMGNGARGARCAY GCNATHGAYGARGCNGTNAARGTNYTNMGNAARTCNTGYGTNAARYTNTAYGGNGGNATH AARCCNYTNAARMGNGARGAYGCNTCNTTYGCNAARGGNTAYGTNATGATHGAYTTYATG GAYCCNGAYGCNGTNGTNCCNYTNCCNCAYCCNGAYGCNGARGCNGAYAARGTNGCNGAR GARGARAARGCNAARGARGARGCNGTNAARGARGARGGNAARGARAAYGARGARATGGAR GARGARAAYAARCAR--------------------------------------------- GAYGTNGARAAYAARCARGARGARAAYAARCARGAYGTNGARAAYAARCARGARGARAAY AARCARGAYGTNGARAAYAARCARGARGARGCNAARCARGARGAR------GARGTNAAR CARGARGGNGAYGTNGAYGCNGAYAARGARAARGCNGARGGNGAYGARGCNAARGAYGAR AARGCNAAYGARGARGGNAARGARAARAGYAARGARGARAARGARAARGARGARMGNAAR AARAARGARTCNAARCCNCCNYTNATGYTNGCNCCNCAYAARTTYAARAGYTTYMGNACN GARYTNMGNAAYATHATGTTYATHAARGCNGAYATHGCNGAYCCNATGATHGTNGCNACN ACNGCNTTYGAYYTNATHATGGAYMGNAARCCNYTNTTYACNGAYTGYATHAAYCARATH YTNCCNGTNCAYGGNGTNTGYGAYAAYGAYTAYAARCARYTNGARATHATGTGYMGNAAR GTNYTNGTNCCNTAYGTNGGNGARCAYYTNGARGARGCNCCNAGYTTYGGNGTNATGYTN GTNGAYAARATGTGYGARCCNGGNGCNGARGTNYTNYTNGARGTNGTNMGNAGYGTNATH TGGTGYYTNAAYCCNGGNGCNTGGCARTGYTCNCCNTGGTGYGARCCNGAYGTNGTNATH CAYATHGARATHATHGGNAGYAARATHATHYTNAGYGCNATGTCNCARTAYATGAARTAY MGNCARTAYAGYCCNTTYGCNYTNCAYGARYTNGGNCAYGGNAARCCNGARGAYGARGAR ------AAYYTNYTNAARGARMGNAARAAYGARAAYGARGARMGNMGNGGNMGNAARMGN MGNGAYGGNAARGAYTGGAARGGNAARGAYGARTCNTCNGGNAARAARAARGARCARGAR AARGAYCARGARGARAARAARGARGAYGGNGAYGARGGNAAYAARGARGARCCNAARGAR AARYTNGARGARGARGARGARGARGARGARGARGARGARAARAARGARTCNGCNGCNACN CCNGAYGARAAYAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARYTNATHTAYAARMGNGGNGCNAARACNAARMGNAAYTGGTAYAARCCNCAY YTNGGNGARTCNYTNGARGTNGARGCNAARAARACNAARAARGGNATHTCNCAYGGNCAY GGNATHMGNYTNMGNCARYTNAGYCAYGTNYTNTAYGAYAARATHACNGAYATHATHAAY ACNGGNGARYTNTCNCARGAYATHYTNGARAAYCARGTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CCNYTNCCNCARAAYTGGGARGCNMGNTGG GAYMGNAAYCARGGNMGNTAYTTYTTYATHAAYCAYGTNACNAARGARACNCARTGGGAR GAYCCNMGNGGNACNGTNCCNCARCCNGCNCARGCNGCNGCNGCNTCNGCNACNAAYMGN AAYGCNTCNMGNCARACNAGYGCNCAYCARGARTCNAGYATGTCNGARGARGTNGAYCAR ACN------GTNGTNGARAARYTNCAYMGNGAYTTYCCNAAYGCNACNAARGCNYTNATH TGYGAYATGYTNATHAGYTGYTAYAAYAAYGARMGNGARACNMGNGARCARYTNAAYGAY YTNGGNTTY---GCNGCNAARTCNCCNGCNMGNCARGTN--------------------- ------------------------------------------GTNTGYCARMGNCAYAAY YTNTAYATHAAYTTYACNGARATHGGNGGNAARAARYTNYTNATHGCNCCNGARGGNTAY MGNGCNTTYTAYTGYGCNGGNGARTGYTCNTTYCCNYTNGGNATHCAYATGAAYTCNACN AAYCAYGCNATHGTNCAR------------------------------------------ ------------------------------------------------------------ ---------------------CCNTCNAGYCARTTYTAYAARYTNAAYYTNCAYTCNAAY ATHTGGCARAGYATHMGNACNCCNGGNAGYCCNCCNYTNAGYCAYCAYGCNTGYGTNGTN GGNGARGAYMGNTAYATGATHYTNGTNGGNGGNTGGACNGGNAARMGNMGNAGYGCNGAY GTNCAYATHTAYGAYGTNCARGARGAYAARTGGYTNCCNGTNAARCARMGNGGNTTYCCN GARGGNGCNGGNYTNAGYTCNCAYACNGCNACNATGYTNACNAAYGGNGAYATHYTNATH ATHGGNMGNGARGGNAGYYTNMGNATHCARMGNAARCAYGGNAAYGCNTAYATHYTNAGY GGNAGYGTNYTNTCNGGNCARTTYGTNTAYMGNGARTAYAGYAAYAAYGTNACNTCNMGN TCNGGNCAYACNGCNGAYYTNATHAGYCAYTCNGTNTTYATHYTNGGNGGNMGNAGYGAY AARYTNTTYGARAARGCNTCNGGNTTYAARCCNCARATHGARCCNAARTCNAAYGTNYTN GAYTCNATHYTNAAYGCNATHTTYACNAARMGNGCNAGYCCNATGACNAARYTNCCNTGY GGNMGNAARAAYCAYGTNACNGCNGCNAAYCAYTCNTGYATHYTNGTNCAYGGNGGNGAR ACNTTYGAYGGNMGNAGYMGNGARCCNGTNGGNGARATGTTYGTNATHTCNYTNGCNTCN CCNACNAAYTTYTTYAARYTNAAYACNAGYAGYGCNMGNMGNGCNGGNCAYGTNTGYTGY GTNTCNGARGAYMGNATHTAYATGCAYGGNGGNTAYAGYGGNCARTCNAAYATHAAYTCN GAYYTNTAYCARYTNGARTTYGARGCNCARGARGAYGCNAARATHGCNGGNYTNAARAAR TCNCARTCNGGNACNMGNCARCARCCNATGGARGGNYTNATHYTNAARTTYACNAAYGTN GTNAARGGNTAYCARTAYMGNTGGYTNGTNYTNGAYCCNGARTCNGGNATGYTNGARTAY TTYGARAARGARGARCAYAARACNCARMGNCCNMGNGGNTCNGTNCAYYTNGCNGCNGCN GTNGTNTCNCCNTCNGARGARGAYTCNCARACNTTYATHGTNAAYGCNGCNAAYACNGAR ATHTAYAARYTNMGNGCNTCNGAYGCNMGNGAYMGNCARYTNTGGGTNGAYMGNATHMGN TCNACNGCNGARCAYCAYACNGCNCAYATHGCNCARCAYTCNCCNAARYTNGTN------ ---MGNAAYGAYTCNTTYACNTCNTCNTCNACNMGNMGNCARGAYTCNGGNMGNMGNACN MGNGGNTCNATGGARAGYYTNCCNACNAGYAARMGNTCNCCNMGNGAYGARGCNTTYCAR GARGTNAARGARTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATHAARAARATH ATHCCNAARAAYGAYAARGARTGGGARTGGTGGATHAARTTYMGNAAYCCNCARGAYATH YTNAARCAYCAYGARACNTAYYTNTAYTGYGARGTNGCNTTYTAYGTNYTNGGNTTYYTN ACNYTNTGYCAYGCNYTNTCNAGYGGNGGNMGNTAYAARTGGYTNTGGYTNGCNACNATH GCNCAYGGNYTNACNGTNGARGCNGTNAGYTAYTAYYTNCCNGAYATHGAYAAYTTYTGG CAYGGNCARTCNATGGTNATGYTNATHGGNCARMGNYTNCCNYTNCAYATHYTNYTNGTN TAYCCNGTNTTYATHTAYACNGCNATHGTNGCNGTNTCNCAYATGAGYYTNAARTGGTGG GCNGARCCNTTYGCNGTNGGNYTNTCNGTNGTNYTNYTNGAYATHCCNTTYGAYATHATG GGNATHAARYTNYTNTTYTGGTCNTGGCAYGAYGAYGAYCCNAAYATHTAYGAYMGNCAY TAYTGGGTNCCNTGGACNTCNTAYTAYTTYCAYGCNGCNTTYGCNTCNTCNTTYGCNYTN ATHTTYTTYGGNTCNAARAARYTNTTYTGYTCNMGNGCNYTNAARTTYCARAGYAGYGGN TTYTTYYTNGARATGYTNATHGTNATHYTNACNGGNYTNYTNTCNATGCCNYTNGGNGTN YTNCARTTYATHCCNGTNTAYCAYCCNYTNCAYGAYACNYTNGGNATHCAYACNGARGTN TGYGTNYTNYTNTTYYTNTCNTTYTAYGCNYTNATHATGTGGAGYTCNGAYMGNMGNCCN TTYGARTTYGCNMGNCAYAARGGNGGNAGYYTNTTYAGYYTNACNATGYTNGTNGTNYTN YTNCAYTAYGCNTTYTAYGTNTTYYTNGTNTTYACNGCNGAYCCNTCNAARGCNMGNTCN ATHGGNYTNCAYCARCARGTNGGNCCNTGYAAYAARCARGTNGAYGTNAARACNCCNTTY GGNCAYGTNYTNAARAARAAYCAYTAYYTNTGYYTNAARAGYTAYTCNGARGAYTAYTTY ACNYTNAAYTGYATGAARAARCCNCCNGTNAAYAARACNGARTGGTAYACNATHTGYGGN ACNCCNTAYCCNAAYCAYAARGARTAYATGGTNATHATHTGYGCNTTYTGYACNYTNGGN YTNTTYTGGTTYTAYCARGCNYTNTGYMGNTCNGGNYTNCARCCNMGNGTNGARTCNAAY AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CARATHGCNGTNYTNTAYATGGCNACNMGNYTNTAYATHAAYATHAGYCARGTN TAYTTYTCNATGTAYYTNACNGARACNATHAARYTNCAYAARATHTAYATHGCNATHYTN CCNYTNTTYACNAAYTCNTCNAGYTTYYTNACNTCNATHYTNGCNCCNTTYGTNAAYAAR YTNYTNGGNMGNAARATGACNTAYTTYGTNGGNYTNYTNTTYGGNTTYGGNGCNACNGTN TGGATGTAYTTYYTNGGNAARCARAGYCAYCARGTNTAYGGNGCNGCNGTNYTNYTNGGN GTNGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTNACNATHATHYTNTTY--- ------GARGARGARGAYYTNCCNCCNGGNGTNMGNAARCAYAAYMGNTGYCAYAGYAGY AGYTCNGARGAYGARTCNAAYAARAARAARCARCCNGTNGARGTNGAYTCNTCNGAYTCN GAYTCNGAYAARTCNGAYCAYCAYTCNTCNAARAARGAYAARCARAARGAYGGNCCNCAR GCNGTNAARGGNAARTCNAARTCNMGNAGYMGNGARTAYTCNAARGTNYTNYTNCAYGTN TCNMGNTCNGAYTCNMGNTCNMGNTCNCARTCNTCNCCNAARMGNMGNMGNTCNCCNGAR MGNAGYMGNMGNTCNMGNTCNMGNTCNMGNGAYMGNMGNCAYMGNMGNGAYMGNAARCAY MGNTCNTAYMGNTCNMGNTCNAARGARMGNMGNMGNTCNMGNGAYMGN------CAYMGN CAYAARAARGAYCAYAARMGNAGYMGNAGYMGNAGYMGNGAYMGNMGNGAYMGNMGNCAY GAYMGNMGNAGY---AGYMGNGAYMGNGAYMGNMGNCARMGNAGYMGN------------ ---------MGNAGYMGNAGYMGNGAYMGNMGNMGNAAYAGYMGNAGYYTNAGYCCNCAY AGYGGNAAR------GTNATHAARTTYGGNGAYAARGTNATHAARCCNGGNGCNAGYTTY GGNMGNCCN------TCNTCNAAYTTYTCNAARCCNGTNACNTTYAARGARAARATGMGN CARCARYTNATHAARGCNATHGARGARGGNGCNGAYACNAAYGARGTNYTNGCNAAY--- AARGGNTCNACNATHTGYACNCARTCNGCNGGNYTNCARCARTCN------ATHCCNAAR CCNAARGGNCCNCCNGTNCCNYTNATGGAYACNATHGTNCCNTCNACNGCNAAYYTNGCN GCNATGACNGTNACNGCNTCNGARGCNGCNATGCARTCNATGYTNGCNYTNCARAARGAR GCNACNGARAARACNGGNATHGARATHCCNAARTAYTAYAAYCCNGCNGCNATHAAYCCN ATGAARTAYGCNGARCARGTNCARAARMGNAARYTNYTNTGGTCNAARGCNAARGAYAAR GAYGTNAAYTCNCARTGGCAYGCNACNAGYYTNTCNGGNGAYGCNGAYGAYAARTCNAAR GARAARTTYMGNAARYTNATGGGNATHAAR------------GAYGARCCNGTNACNGCN ACNGARACNGGNGARGGNGARAARYTNGARAARCARAARCARYTNTTYGAYCARYTNAAY AARGARTAYGARTTYGCNMGNATGGCNACNCAYACNCAYMGNGGNATHGGNYTNGGNTTY AGYTCNTCNTCNTAYCARCARCCNCCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CCNYTNCAYATHGCNGCNTTYAAYGTNMGNCAYTTYGGN MGNGGNTTYATGGAYMGNACNGARAGYGTNGCNCAYYTNGTNAARATHATGGAYMGNTAY GAYATHGTNYTNATHCARGARGTNMGNGAYGGNTCNAAYACNGCNYTNGAYGARYTNYTN ACNAGYYTNGGNTCNACNGGNAAYTCNTGGAAYTAYGTNGCNAGYCARCCNYTNGGNMGN TCNAARACNTAYAARGARCARTAYGTNTTYTTYTAYAARACNACNGCNACNACNATHYTN AARACNTAYCARACNAAYGAYACN---GCNGAYATHTAYGARMGNGARCCNTTYTGYGTN CARTTYGARTTYGARTCNTCNAGYCARAAYGTNMGNGARAGYGTNGTNYTNYTNGCNYTN CAYACNMGNCCNGTNGAYACNAARTCNGARYTNCARCAYYTNCCNGCNACNGTNAARTCN GTNGCNAARGARTTYCCNTCNTCNATHGGNGTNATHGCNYTNGGNGAYATGAAYGCNGAY TGYMGNTAYYTNACNGGNACNTGGMGNGAYTCNYTNGAYATHTTY---AAYGGNGCNGAY TTYAAYAGYYTNATHCCNGAYTCNGCNGAYTCNGCN---ACNMGNGARACNGAYTGYGCN TAYGAYMGNGTNGTNYTNTAYGGNAARACNATHGAYGTNMGNAAYGCNTCNGTNTTYAAY TAYCARACNTGGYTNAARYTNGAYGARGGNGCNGCNYTNAAYGTNAGYGAYCAYTAYCCN GTNGARTTYTAYYTNTAY---TTYAGYYTNAAYYTNTGYGTNGGNCARACNTAYGAYCAR GAYTGYGCNYTNCAYTTYAAYCCNMGNYTNGAYGAYAAYAARGTNGTNMGNAAYCAYATG CARGGNGGNAGYTGGGGNAAYGARGARACNAGYGGNGGNTTYCCNTTYMGNAARGGNATG CAYTTYGARATHCAYATGAARGCNAAYCAYCAYGCNTTYAARATHACNGTNAAYAAYMGN CAYTTYTGYGAYTTYAAYTAYMGNYTNCCNMGNGARAGYGTNCARTAYYTNTAYATHGAR GGNGAYGTNATHGTNACNTAYATHCARTTYMGNGGNGGNCAYCCNCARCCNTCNGGNGTN CCNGGNGGNTAYCCNAAYTAYCCNCCNGCNGTNCCNGGN--------------------- ---GCNGGNGCNGGNTAYCCNCCNGCNCCNAAYTAYCCNTCNGCNCCNGGNTAYCCNTCN GGNGGNGCNGGNCCNATHTTYAAYCCNCARGTNCCNTTYACNACNCCNATHCARGGNGGN GTNGTNCCNGGNMGNATHGTNTTYATHTCNGGNATHCCNAAYCCNACNCCNAGYMGNTTY TCNYTNAAYATGCARTGYGGNCCNTAYGAYTCNGGNGAYTTYGCNYTNCAYTTYGAYGTN MGNTTYAAYTAYGGNAAYTGYGTNAAYCARGTNGTNMGNACNCAYAARCARMGNGGNGGN TAYGGNCCNGARGARAARGAYATHACNTTYTTYCCNTTYTAYCCNAAYACNCCNTTYGAR ATGATGATHYTNATHGARCCNGCNTCNTTYAARATHGCNGTNAAYAAYCARCAYTTYGTN GARTTYTAYCAYMGNATHCARCCNTTYAAYMGNGCNGAYCAYGTNCAYGTNATGGGNGAY GTNMGNYTNACNCARGTNMGNTTYCAR---------TTYATGCCNAAYTTYYTNGTNAGY TCNGGNACNGGNYTNACNCCNACNYTNACNCCNAGYACNYTNGCNAAYATHGARCARTCN TTYATGGARATGCARCARTCNGGNGCNMGNGAYCCNGTNACNCARAGYGGNTTYGTNCCN CCNGTNGTNGARCCNTCNAAYAGYAAYAGYGCNGAYYTNTCNCARGAYAGYTTYGARAAY TCNTCNTCNGAYCCNGARTGGGARCCNAGYGCNAARAARYTNYTNATGAARGAYGGNGTN AARGGNGTNGAYTAYATHGTNACNTCNACNGGNACNATHAAYGTNGCNCCNCARMGNAAR TAYACNMGNMGNAAYAARGAYGARAARTCNAAYCARTCNAAYGAYGARAARAAYTTYGAR TCNGARATHGARAARCARMGNAARATHGGNGARAARMGNYTNACNTCNTGGYTNCAYAAR GTNGGNAARGTNAARAARAARGTNTGYGAYGARAGYAARGARAARCCNGCNCAY---ATH MGNATHAAYGAYTAYYTNTGYAARYTNCARAAYTAYATGGCNGTNATHTCNGARATGTCN TGYCARGTNGARAARATGGAYTCNATGGTNTCNGAYGCNGAYAARTCNTCNTGGCARAAR GARTGYGAYGTNATGGARACNYTNAARACNAARCAYMGNACNYTNCARMGNYTNATHGAY AARMGNAAYGTNGARCARGTNGARAARAARYTNYTNMGNACNAARCARMGNAARACNMGN YTNAARAARTCNMGNCAYYTNTGGTTYCARGARMGNCARGCNATHGARGARGCNMGNCAR GARAARGARAARGARATHAGYGAYTGGCARYTNAARYTNYTNTCNGARATGAARGARGAR YTNYTNAARAARAARMGNAARCARGARATGGAYCARACNYTNAGYGARGTNACNAARAAR ATHCAYGAYGCNAAYMGNYTNATHGAYACNATGACNTCNYTNGARAARYTNMGNYTNATH MGNCARGAYGCNGCNAARAARMGNGGNGAYATHGAYYTNGGNGARTCNMGNCARAGYTTY GARCARAARATHGCNGAYATGACNMGNYTNGTNCARTCNCARYTNGARGTNTAYAARGAR GARGARCARCARYTNMGNAARGARATHAARTCNGARCARGARGARAARAGYAARAAYGAR AARGARYTNCARGARATHAARGAYAARGARGARCARMGNAARAAYGAYGARGAYYTNCAR AARATGYTNTTYGGNATGGARAARGAYATHGAYGAYYTNYTNGAYGARGTNGARTCNAAR TAYGTNAARCAYTCNAARCCNGARYTNAARGCNAARGCNGARCCNACNTCNAARCCNAAR CCNAARCARACNAAYACN---GTNGAYGAYGCNATHAGYGAYATHYTNGAYYTNGAYYTN GAYGAYGGNATHACNGCNAARAARGGNATHCCNGGNAAYAAYCAYCCNACNTCNACNYTN ACNTCNATHGGNGARAARAARGARGCNACNAARAARTGYTTYCCNGTNTCNYTNGGNGGN AGYATHGAYGARACNGGNYTNGGNACNACNGTNAARACNMGNGCNTGYGAYCARYTNMGN TGYACNGAYTGYGAYTTYMGNGTNTGYTAYTTYGAYGAYTTYTCNTGGAARAARGARACN AAYTAYYTNTTYYTNMGNAAYAAYGTNCCNAAYTTYCARAARYTNAARTCNAAYYTNMGN MGNCARAARGGNTGYMGNGCNTAYTGYTGYCARTGYAGYTGGMGNGAYGTNCAYTCNATG CARGARATHTCNGAYTCNAARYTNAARTGGGTNTGYGGNAARCAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNGARTGYCCNTAYAAYAARGAYCAY AARATHTCNTCNYTNMGNATGCCNTAYCAYYTNTAYMGNTGYTGGAARAAYTAYCCNGAY GTNGARATGGCNATHTGYCCNTAYAAYGCNAGYCAYGARGTNAAYAARCCNGARYTNAAR TAYCAYATGACNCAYTGYCCNAAYMGNACNYTNYTNGARMGNAAYYTNTCNTAYAAYGAR YTNCARAAYGCNATHYTNGGNAARGARGARGTNGCNMGNAARGGNAAYACNGARYTNCCN TGYCCNGTNGARCCNACNCAYAGYCARGAYGAYGAYYTNGARAAYTGGGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNMGNAARAGYATHTTYACN ACNGTNAARAARAARATHCCNGAYTGYAARGCNYTNYTNGTNAARATHGTNCCNGCNCAY GGNYTNTTYCARGTNYTNTGGACNCAYCARAAYGCNCAYGGNAARGGNYTNYTNGARAAY TGYTCNTGYCARAAYGTNTAYACNACNGCNAARGGNTGGTTYGAYCCNTCNYTNCARTCN GTNGAYTAYYTNTCNGGNTTYGTNGAYGCNCCNGARGARAARGARGGNTTYCARATHAAR GARGTNGAYGCNCARTTYCARGTNCARTCNGAYTTYAARTGYGARGTNCCNGCNTTYTTY GCNCARTGGGARGCNGCNGTNACNCCNACNGGNGAYYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNGTNAAYTCNCAYTAYGTNYTNYTNCCNGARATHCCN CCNGAYACNGCNGARACNAAYACNGTNATGMGNATHGAYCARYTNCCNCARTTYTCNCAR ATHTCNCCNAAYACNTGYATHACNGCNTGYGCNAARYTNTCNATHGARTAYGARACNAAR YTNGARAARCAYATHGARAARYTNAARGAYCCNAARTCNGARAARACNTTYGARGAYATH TAYTTYCCNYTNGARGAYATHGCNATHCCNYTNAAYACNGCNTGGTCNACNGTNMGNAAY YTNCAYTAYGTNGCNGCNAGYGAYGAYTAYMGNAARGCNTTYTCNAARGTNCAYCCNCAR GTNGARMGNGTNAARAAYGARMGNTGGGTNAGYCARCCNYTNTAYTAYTCNTTYAARGAR YTNGARGCNAAYAGYGCNAAYYTNGAYGARTTYCARAAYMGNYTNGTNAAYYTNTAYYTN YTNGARGGNAARYTNAAYGGNGTNCAYYTNTCNGCNAARGARAGYTCNGARYTNGTNAAY CAYYTNAARYTNATHGCNCARGARGGNCARCAYTTYMGNTAYAARGTNMGNYTNTGYACN GARYTNTTYTCNCAYGAYGTNACNAAYTTYAAYATHATHGARGARATGCCNTGGCCNYTN YTNGCNCARATGTCNAARGAYMGNTCNAAYCCNACNMGNGGNCCNTGGMGNGCNACNYTN CARCCNGCNATHTAYCARGCNATGATGACNTAYTGYAGYCAYMGNYTNACNMGNTGGAAY YTNTGGAAYGCNTAYCAYAAYMGNGCNTCNCAYAAYTAYGCNCAYMGNTTYYTNAAYAAY AAYAARYTNATHGARAGYYTNMGNTCNTAYMGNGCNGARGTNGCNACNATGYTNGGNTAY GAYAAYTTYGCNGARATGTCNATGGARACNAARATGGCNGGNTCNGTNAARAAYGTNYTN AGYATGATHGARACNYTNAARGCNMGNTTYGCNCCNGCNGCNTGGGAYGARGTNGCNCAR YTNCARCARTTYGCNACNTCNGARGGNTTYGARCAYTCNYTNGARATGTGGGAYATHGGN TAYTGGMGNMGNMGNCARMGNGARCAYYTNTTYAGYGTNAAYAARGAYACNGTNAARGAR TAYTTYCCNATHAAYTCNGTNYTNYTNGGNYTNTTYGAYYTNTGYGCNAAYYTNTTYGGN GTNAAYTTYGARGARGTNACNCCNGARGTNGARGTNTGGCAYCCNGAYGTNMGNTTYTTY AAYGTNYTNGAYGGNGARAGYGGNGARCAYATHAGYTCNTTYTAYTTYGAYCCNTTYGAY MGNCCNGGNAARATHTCNTCNGGNTAYATGGAYYTNGGNMGNGAYAAYAGYGAYCAYGTN GGNACNTGGCCNTAYTCNTAYYTNTGYYTNAARATHCCNMGNATHAARTCNTCNTCNGAY CCNGCNYTNATGMGNTTYGARGAYGTNGARATGYTNTTYACNGARTTYGGNAAYGGNYTN CARCARATGYTNACNAARGTNCCNTAYAGYGARATHGCNGGNCARAARAAYATHGARTGG GAYGCNGTNCAYGTNTGYGCNAARTTYATGAARAARTGGYTNACNGTNCCNGCNGTNGTN AARAGYYTNAGYAGYCAYTAYAGYAGYGGNGARCCNATHCCNGAYGAYYTNYTNTCNAAY ATGYTNAARGCNTCNCARCAYTGGAGYAAYTTYGAYATGATGTAYCARYTNTAYGTNTCN GCNTTYGAYYTNGARATHCAYATGACNAARACNCAYTGGCAYAGYGTNATGMGNCARYTN TGGGARAAYTTYATHCCNYTNCCNYTNTGYGARGARGAYAAYYTNCCNTGYTCNATGYTN CCNATHTTYTGYGAYATGTAYCCNGCNGCNTAYTAYTCNCAYAARTGGTCNGARATGATH GCNGCNGAYGTNTTYTCNGCNTTYCARGARGCNGGNYTNGARGAYCARGARAARYTNAAR GTNYTNGGNAARMGNTTYMGNGAYACNTAYYTNTCNYTNGGNGGNGGNGTNCCNTCNTGY GARGTNTTYMGNCARTTYMGNGGNMGNGAYCCNTCNACNCARGCNYTNCARCCNATGGAR AAYAAYAAYGCNATHGCNGCNAARACNGARYTNGAYGGNGARACNAARATHGARAAYGTN AARCCNACNGCNGAR------GAYAAYGAY---------------TCNTCNCCNMGNMGN MGNCARCARATHMGNMGNGAYGTNAAYCCNGARGAYGARACNGGNAARGCNGCNATHMGN MGNAARATHTGGGAYAAYYTNGAYGAYAAYAAYYTNGTNTCNGCNCCNMGNCCNTGYCAY TAYMGNATHCCNAAYTTYGARGGNGCNGCNGCNGCNGCNGAYMGNYTNACNTCNYTNGAY GTNTTYAAYAARGCNMGNACNATHAARGTNAAYCCNGAYAARGCNCARGARCAYGCNMGN TTYYTNGTNYTNGARGCNGARAARGAYYTNGTNYTNYTNAAYCARAAYCARAARGAYYTN ATGGTNCCNACNCCNCARYTNAARTCNGGNYTNYTNAAYMGNATHGTNCCNCCNCARGGN GCNAAYAARGARGARYTNMGNCAYTCNTGYACNACNCARGGNGTNAARGARAAYAGYAAR GARATHGGNYTNGARGAYAARGTNAARYTNGAYYTNATHGTNGTNGGNAGYGTNGCNGTN TCNMGNAGYGGNYTNMGNATHGGNAARGGNAARGGNTAYGCNGAYYTNGARTAYGCNATG ATGMGNACNATGGGNGCNGCNGAYGCNAAYACNGTNGTNGTNACNTCNGTNCAYGAYTCN CARGTNGTNGAYATHTCNGARGARYTNGTNGARGARCAYGAYATHACNGTNGAYTAYATH YTNACNCCNACNGARGTNATHAARACNAAYTGYAAYMGNTCNMGNCCNTCNGGNGTNATH TGGAAYCAYYTNGARATHAAYAARTTYTAYCARATHCCNGTNYTNMGNCARYTNMGNAAR AAYGARMGNGAYGCNGGNAARAAYGTNATGYTNAARGARCARAARGARGARGAYGARGAY CCNGTNGAYACNATGGARCCNCCNMGNCCNMGNMGNTAYGTNMGNTAYTAYCARAAYGAY GGNGGNTAYMGNGGNMGNGGNMGNAAYTAYGGNMGN---TAYMGNMGNGGNGGN------ MGNMGNMGNTTYGAYGAYGGNGAYGAYAGYAAYAARGARAAYCARGAYGGNGGNGARGAY TCNGGNGCNGAYGGNGAYAAYGARGGNMGNGTNGGNAAYMGNMGNCCNCCNCCNMGNAAY AAYTTYMGNAAYMGNMGNTTYMGNMGNGGNGGNGGNGGNAARATG---MGNGCNTCNGAR TCNGARCAYAGYGAYGGNGGNGCNATGGAYGGNAAYGGNGAYGGNGARGAYMGNCCNMGN CARMGNMGNTAYAAYACNAAYMGNMGNMGNTTYAAYCCNAAY---AAYMGNMGNMGNMGN TTYGAYGGNAAYMGN------MGNGAYAAYMGN---MGNGAYGAYCAYTCNGGNAGYGAY GGNGARCARAARAAYTCNGCNGAYGARGAYGGNGARGGNMGNMGNCCNCARMGNCARMGN TTYMGNACNAAYCCNGARGCNGTNGTNTTYGTNGGNGCNYTNTCNMGNAAYYTNMGNGTN AGYGARYTNAARACNGARYTNMGNAGYCAYAAYGTNAAYCCNATHMGNYTNYTNTGGMGN GGNGGNMGNGGNTAYGCNTTYYTNTTYTTYATGGARTCNGAYAAYGCNAARGARGCNGTN GAYGTNYTNGCNGGNMGNGARYTNAAYGGNMGNGARATGAARGTNGARATGGCNAAYATG GAYMGNGAYMGNMGNMGNTCNAAYMGNAAYGAYMGNGGNMGNGAYGARGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNYTNAGYTAYGGNATH GGNMGNTTYTCNACNTGYCCNATHGCNMGNTAYCARYTNGCNYTNYTNYTNGTNYTNMGN GARAARYTN------CCNCCNTGYYTNGTNTAYGAYCCNGTNTTYTCNTCNGGNGARAAR GCNGTNYTNGARGAYYTNGGNTGYAGYGTNATHCCNCAYAAYGARGARGGNAARMGNATH TGYGAYTGYCCNACNATHYTNTTYATGCCNCAYTGYGGNAARGCNYTNTAYAAYAAYGTN ATHTGGGCNAAYYTNTCNACNYTNAGYAAYYTNGTNATHATHGGNAAYAGYTTYTCNMGN ATGYTNGARAGYACNCCNCAYMGNYTNYTNATGCARACNGCNAAYTAYGTNATHAARACN GCNCCNTAYATHGARGARACNCCNYTNAARTCNTCNTCNTTYGTNCAYTCNGAYGTNTTY AAYGAYYTNTCNYTNCAYATHTTYCCNAGYTCNAARYTNAARACNGCNCCNAARGARTTY TGGCARGGNAAYACNGARCCNGARTAYGAYAARGARGARGTNGARATHATHMGNAARGAR YTNAARCARAAYCAYCARACNCARYTNAAYAAYYTNACNAARGARCARGAYGCNCARYTN CARAARATGAARGARGARTTYAAYCARAARATHGGNTCNGARCARCARMGNYTNACNTCN GTNYTNGARTCNGARAARGTNACNYTNCARMGNAARCAYGARMGNGARGTNGARGAYACN AGYAARAARTTYACNGTNAARATGGARGCNYTNAARGAYAARYTNGAYGAYGARGAYGAR GARATGMGNGARAARAARGCNGAYATHGARMGNMGNATGTCNTAYGTNGARAARTCNATG AARATHYTNGARTCNCARGARGCNAARYTNGARGARMGNMGNAARAARTTYACNAAYGAY AARGARMGNYTNGARCARGAYCARGAYGARGTNYTNGGNTCNAARGTNTCNAGYYTNGGN GTNGCNGARYTNGAYMGNATGMGNGARGARMGNMGNCARYTNTCNCARGARYTNMGNGGN GARCARAGYCARYTNGAYAAYGTNAARMGNGARMGNAARACNYTNGARGGNGAYGTNACN MGNYTNAARATGGCNMGNGARCARCARAAYAARAARYTNTGYGARATHMGNGARMGNGTN GARACNAARYTNAARGARTTYGARGGNYTNCARGAYMGNTTYACNAARGARGCNGCNGAR GARGGNCARMGNGCNTGGGCNGCNAAYTCN------------AAYTTYTCNACNGCNCCN TCNTCNCCNTCNAARYTNAAYATH------------------CARTCNTAYCAYCCNGAY TCNAAYACNGTNYTNAGYGARGAYGAYGAYGAYCCNYTNMGNGGNGTNCAYMGNATHAAY GARTTYAARCCNACNAAYCAYTGGTAYAGYAAYYTNTCNATGGARCCNGAYGAYYTNACN ACNCAYYTNAAYMGNAAYGAYMGNAGYGGNATHAARGARTAYYTNCAYAARGARGGNGTN GTNATHGCNMGNGCNAARACNTTYYTNCARAARCARMGNMGNACNYTNAARCARMGNCAR TCNGCNATHGCNGCNGCNAARCARGARYTNAAYAARGAYAAYAGYATHYTNGARCARACN AAYCCNACNAAYGARGCNACNGARATGYTNGARAARGTNMGNGAYACNYTNGARTCNGAR ATGGTNCARATHGAYGCNYTNCARTCNAARTAYGAYTCNGARTCNAARATHYTNAARGAR AARGARGARAAYTAYCAYMGNYTNGARGGNYTNACNAARGARAAYGAYAGYGARGAYGAR TCNGARTAYAGYCCNTTYGGNMGNCCNTTYCAYGGNGTNAARATHCCNAAYATHGAYYTN AGYGARGAYGARAGYAGYGGNGTNAGYAGYTCNGARGCNAGYYTNGAYGGNTAYTAYCAR AGYMGNCAYMGNCARTTYTCNAGYACNACNMGNACNAAYGAYGCNYTNGGNTCNGGNACN GAYGAYYTNTCNAARGCNYTNTAYMGNATHAAYCAYGAYYTNTCNCAYGTNYTNAGYGTN ATHGGNAARGAYGGNGAYTCNGTNYTNGGNAAYTCNYTNCCNMGNCCNCCNTCNTCNCAR MGNTAYCARGGNYTNCCNGARGGNGTNCARTGGTCNCCNCAYCCNCCNAGYCARCCNTCN TCNAARGAYTAYTCNACNYTNGTNGCNACNGCNGARCAYTCNYTNGARMGNAARTGGMGN AARTAYTTYGGNGAYMGNMGNCCNCCNTTYACNGCNGTNCCNTCNCAYYTNTCNTCNATH MGNGGNTTYAGYTCNACNTCNAGYYTNTCNMGNGAYACNAAYTTYTCNMGNCCNGCNTAY TCNTCNATHCARTCNMGNYTNGAYGARCARAARGARTGGYTNMGNCARCAYCAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNYTNGCNMGNTTYAARGAYTGYGAYGGN YTNCCNMGNGTNAARYTNAGYGGNCCNGAYGARTTYTTYTCNTCNATHGARMGNGARGAR YTNAGYATGYTNTGYMGNTGGMGNGGNGARYTNTAYYTNGARYTNCAYAAYGGNACNTAY ACNACNTGGGCNCARGTNAARAARTCNAAYMGNCARTGYGARATHYTNYTNCARGARGTN GARGCNATGTCNTCNYTNGCNTGYYTNAARGAYTCNAARTTYGTNTAYCCNCAYGAYGAR YTNGAYMGNYTNTGGAARYTNYTNYTNYTNAAYCARTTYCAYGAYGTNYTNCCNGGNACN TCNATHACNCARGTNTAYAARGAYGCNACNAARTAYTAYCARGAYATHCAYAAYTCNGGN TCNMGNATGTTYGAYGCNGCNGTNACNGCNATHGTNGGNAARGARMGNATGGAYCARGAR GGNTCNTTYCAYACN------ATHGTNAAYACNCARGGNTTYGARMGNTGYGARGTNATH GARATGTCNCCNTGYAAYGAYGARGGNAARTCNYTNGCNGCNAARMGNMGNGARGAYGGN GTNAGYAARAARGTNAARGTNCCNGCNYTNTGYATGMGNTCNYTNGAYGAYTGYGTNGTN GARTCNGTNTGYYTNATHAARCARGGNGAYAAYTTYGTNYTNGARAAYAAYYTNYTNMGN GCNGTNATHGAYCCNYTNGGNMGNGTNATHTCNYTNAARTGYGTNGAYCCNAAYGAYAAR AGYGTNACNAARGARGCNATHGAYGTNACNCAYCCNGCNAAYCARTTYGTNYTNTAYGAY GAYATHCCNYTNTAYTGGGAYGCNTGGGAYGTNATGGAYTAYCAYYTNGARACNMGNAAR CCNGTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GGNMGNTAYYTNGCNATHGGN GGNMGNAARAAYGCNGARGGNMGNYTNTAYATGYTNCCNTCNGAYCARTGYGGNAARGAY GAYGTNAARGGNTTYGCNMGNYTNCCNCARGAYTGGGTNGGNGTNYTNCARTAYTCNATH GAYACNGARATGAARAAYAAYGARATHGGNACNTTYGAYTGYCCNYTNGTNYTNGAYMGN GTNAARAARGCNYTNATGTTYGGNGCNTCNGCNATHATHATHYTNACNYTNAAYCARCAR GTNATHAARGARYTNGAYGCNTCNCARATGGTNTCNAARCCNATHGTNYTNATHGAYAAY YTNGARAAYATHACNACNTTYYTNACNYTNYTNYTNGGNCAYGTNAARYTNCAYGGNAAR ATHATHATHAAYAGYAARGCNGAYCCNAAYCARYTNTGGCARTGYTTYTAYGCNATHGTN YTNTTYYTNGTNATHYTNACNGGNGTNAARAGYMGNATGGTNGARGGNATHTCNGARCAY GARATHGARTCNAGYMGNMGNAARAARGTNCAYCAYTCNYTNTCNATGATGAARATHGTN AARTAYAARCAYCCNGGNGAYGTNACNYTNCCNGARGAYYTNTGYGCNGTNTGYYTNGAY GARTTYCAYAAYAAYCARAARYTNMGNATHYTNCCNTGYTCNCAYYTNTAYCAYACNMGN TGYGTNGAYCCNTGGYTNGTNCAYAAYMGNACNTGY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGGCNGCNACN------ACNACNGCNACNACNACNAARAAY AAYGTNACNYTNCARYTNGARAARGGNGARTCNGTNACNGGNTCNATHAGYATHGCNAAR CAYYTNCARMGNGARGTNACNGAY------GGNYTNAGYYTNGARGAYMGNATGTCNGTN GARCARTGGYTNGAYTTYAGYGGNGARATHGCNAGY------------ATHGARAARGTN GGNGAYMGNGAYMGNATHCARGTNGTNYTNAARGAYYTNAAYAGYTTYATHAARGAYMGN GTNTTYTTYGTNGGNTCNAGYATHACNGTNGCNGAYGTNTTYYTNTAYCAYTGYYTNTTY CCNATHTTYGTNAARYTNTCNTTYCARGARAARGARAARYTNGTNCAYYTNTCNMGNTGG TTYAAYAAYATHCARAAYGAYGTNAARGCNMGNCARTCNYTNYTNCCNGTNAARTTYYTN MGNACNATGYTNTAYTCNGGNGTNGGNAAYCAYATGAGYGCNYTNGARACNGTNGTNTCN MGNYTNAARAGYATHGCNCCNYTNTCNYTNGCNGARAARTGGGAYAAYGTNGGNYTNYTN GTNGARCCNTCNGGNCCNAARTTYATHAGYCARATHATGYTNACNAAYGAYYTNACNGCN TCNGTNATGGARGARGCNAARGAYAARACNGTNGAYYTNATHYTNTGYTAYCAYCCNCCN ATHTTYGTNCCNYTNAARMGNYTNACNCARGAYTCNTGGAARGARMGNATGYTNATHGAR TGYATGGARAGYMGNATHGCNGTNTTYTCNCCNCAYACNACNTAYGAYGCNGTNGARGAY GGNGTNAAYGAYTGGYTNATHTCNGCNTTYGAYGTNGAYAARGARTCNATHGCNCCNGTN CARATHGARTCNYTN---GTNAARAAYAAYTCNCAYGTNYTNGARGTNGARYTNGARCCN TCNAAYYTNATHGARGTNTGGAARACNATHACNYTNAAY---GTNCCNAARGAYTCNMGN ATGMGNAARGAYAARACNTGYTTYTCNACNCARACNATHMGNACNGGNTCNTCNGARMGN TGGMGNYTNMGNYTNGARTGYAGYCARTCNGARYTNATGGAYYTNATGAARGGNGTNGTN TCNTGYCCNAGYGTNGARAARTAYTCNGTNTCNACNYTNTCNAARGTNTCNCARAGYAAR TGYGGNATGGGNMGNTTYGCNAARYTNAAYGARCCNATHTCNYTNGARAARGCNGTNGAR TGYGTNAARAAYCAYYTNGARYTNAARCAYGTNAGYYTNGCNMGNGTNGGNGGNAGYGAR CAYAAYYTNGTNAAYACNGTNGCNGTNTGYGCNGGNTCNGGNTCNAGYGTNYTNAARAAY TCNAARGCNGAYYTNYTNGTNACNGGNGARATGTCNCAYCAYGAYGTNYTNGAYGCNGTN CAYAAYGAYTGYAAYGTNATHYTNTGYCAYCAYAGYAAYACNGARMGNGGNTTYYTNACN CAYYTNCARAARMGNYTNATHAARGTNATGGARAARTCNGTNCAYGTNTTYGTNTCNGAR TGYGAYAARGAYCCNYTNGARATHGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GCNMGNGTNAARGCNCAYAAYCAYGCNGGNGARAGYGAYTAYAGY GAYGTNGTNAAYYTNCARACNGCNGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TCNAARYTNGARAAR YTNATHYTNAARGTNGTNCCNYTNCARCCNGGNGAYTGYYTNGGNTGYAARYTNGTNGGN ACNTCNGTNATGATHGGNAGYGGNATHATHGTNYTNACNTCNGCNATHGCNGGNMGNAAR MGNYTNTAYGTNGAYGAYTTYYTNGTNTAYMGNAGYAARTCNAARACNGAYACNATHGAR MGNCARYTNCARYTNCARYTNAAYAARYTNAARGAYTGGGCNGAYYTNAAYGGNTTYACN TTYTCNCCNCARAARACNGTNGCNGTNCAYTTYTGYYTNAARACN---TCNTGYACNMGN GAYCCNGAYYTNTAYYTNGAYAAYAARMGNATHGARGTNAARAAYCARGCNMGNTTYYTN GGNGTNATHTTYGAYAARAARYTNAGYTTYYTNCCNCAYATHAARGAYYTNAARATHMGN TGYATGAARGCNYTNMGNGTNYTNAARGTNYTNTCNAGYMGNGARTGGGGNGCNGAYTCN AAYACNYTNYTNMGNYTNTAYMGNGCNYTNGTNMGNTCNMGNYTNGAYTAYGCNTCNTTY ATHTAYGGNTCNGCNAARCCNACNTAYATHGGNATGYTNGAYCCNATHCAYCAYCARGGN YTNMGNYTNGCNATGGGNGCNTTYMGNACNTCNCCNGTNGARAGYYTNYTNGCNGARGCN GAYGARCCNCCNYTNMGNMGNAARCARYTNGCNYTNCARTAYGTNTCNAARACNCARNNN YTNNNNAAYCCNGCNCAYAARCAYACNATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNGGNGTNGARCARGAYATHATHCCN CCNGGNCAYATGTCNMGNGARATHACNAARACNTCNAAYMGN------ATHTCNGTNCCN TCNAARGGNAARYTNCARYTNYTNAARCARGARTCNCAYCARATHGGNCCNGGNCCNGAY TAYGARMGNGTNAARTTYAAYACNTCNGGNMGNAGYCCNYTNATHTCNCAYTAYYTNCAY ATGMGNCARYTNMGNAGYTAYAARCARCCNGGNATGAARGTNMGNMGNACNGARATHYTN AARYTNCCNCCNGAYGGNCCNACNTAYCARCARTTYATHGCNAAYACNYTNAAYAARGCN GARTCNYTNGARAARGARTAYACNMGNATHTGYGAYCARACNTCNAAYGCNATHYTNGAR YTNGARMGNTAYAARMGNGAYTCNAAYAARGARATHGGNGARYTNAARAAYGCNYTNACN AAYATHAARAGYATHCCNGARMGNMGNTCNYTNATGGARAARATHTCNGARTAYAARGAY YTNATGATHAARGARAARCCNYTNTTYGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TAYGAYCCNAAYTAYTTYAGYYTN CCNCAYCCNGCNYTNGGNACNTTYACNATHTGYYTNGTNGCNTAYYTNATHGTNGTNACN GTNTCNCCNAAYAGYYTNCCNAAYTTYYTNTGGCCNYTNACNCARATHGGNAARTAYATG GCNATHAAYCAYTAYAAYTTYTGYATHGGNTGYTGYTGYTTYGCNYTNATHAGYCAYTCN YTNGARGCNGCNTAYGCNGGNAARGTNTCNCAYGAYMGNMGNTAYACNGTNTCNGTNACN ATHAARTGGGCNYTNAGYGTNTTYATHTTYGGNTTYCCNGCNYTNATHCCNYTNCARGCN CAYAARCCNMGNTCNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TGYAGYMGNCAYMGNMGNCCNCCNGCNAAYAARCCN MGNACNCCNYTNMGNGCNMGNGARGCNGARAARAAYMGNMGNATHGGNAAYGTNCARACN CCNCCNCCNMGNAARTCNCARATHGCNGAYGAYTCNYTNTAYTCNGAYATHTGYGARGAR AGYAARCARAGYGGNAAYTAYTTYCCNGTNAARCCNATHGCNAARTCNCCNTCNGGNGGN CAYAARGAYGARATHGGNAARYTNCARYTNGARYTNGARAGYTAYYTNCARACNYTNTGY MGNATHGARCARCARGTNYTNMGNGAYGGNAAYGCNGARTTYYTNCARAAYMGNATHAAR GGNAARGTNAARGAYAAYTAYYTNGTNGARGARCARGAYYTNGAYMGNGCNMGNGTNMGN GCNGGNGARCAYAAYACNMGNTCNTCNMGNAAYYTNTAYAAYYTNTGYCARAARGTNAAR CARYTNCARMGNGAYGTNAGYCARACNGAYYTNAGYAARCCNNNNAARAARAGYCARATH TCNGCNCARYTNAAYGCNACNTAYMGNGGNGCNGTNMGNGCNYTNCARATGTTYGTNAAY CARYTNCCNTAYCARGAYYTNAAYATGGGNYTNCCNTCNTCNTAYAAYGARYTNGCNYTN YTNYTNMGNCARYTNACNACNYTNATGACNYTNACNCARCARGGNTCNAARGTNGARGGN CCNCCNGAYGTNYTNAGYYTNYTNGAYCARGTNGAYGAYTTYAAYTCNAARTGGTGYTCN CARTCNAGYMGNTCNGCNCARCCNYTNCAYMGNAARGTNCCNACNAAYAAYGTNCARMGN GCNTGGGTNAGYGAYACNAARGTNGAYGCNNNNTTYTTYTCNAARAAYGTNACNGARTTY ACNGTNCCNGCNCCNAARAARAGYCCNYTNTCNAARCARCARCAYGTNAARGARMGNAAR CCNMGNGTNGGNGGNGGNAARGARAAYMGNCARGTNTTYATGAAYGARGGNTCNAARTCN ATH---ATGAAYAAYCCNTCNYTNGTNGGNCARAARACNTTYGGNTTYGTNTCNYTNGAR TCNAARCCNGGNCARTCNAGY---------------------GAYATHAGYAARGGNTAY ATGYTNCCNCAYGAYYTNCARGCNAARMGNGARMGNGCNCARMGNGCNGTNGARYTNTCN AAYAARAAYTTYGCNGARTCNACNCAYTCNTCNMGNYTNAARACN---ACNTCNGCNCAR MGNCCNCAYTCNGCNCCNTCNCCNGGNMGNAARAARGARGTNAAYTTYGAYYTNMGNGAY ------GAYTCNAAYACNCCNTGGGTNCCNGCNGGNTGYTCNTCN------MGNAARTCN MGNCCNMGNTCNTCNAGYGCNGARMGNATHCCNTTYTAYGTNAARACNATGGAYGGNCAR GAYGTNTGGGAYGTNATGCCN---GARMGNCCNTCNMGNAGYGTNACNYTNCARGGNAAR CAYMGNGARCCNGARTTYGGNTAYMGNTCNYTNCCNACNGARGGNAARYTNMGNTCNTGY GAYGTNTCNGAYTCNTTYATHGAYYTNATHGARAARMGNYTNTAYMGNATGATGMGNGGN AARACNGARACN---------------------GGNGAYATGMGNCARTCNMGNAARGAY CARATHYTNTAYAGYAGYAAYGAR---------------GCNYTNGAYATHACNGAYYTN ACNGAYACNAGYATGAAYACNACNGCNGARGCNGCNAGYATGGTNGAYGCNCCNACNYTN GARAAYATHCARYTNAARYTNGCNGAYATGGARMGNACNMGNMGNGARATHMGNCARMGN TGGTCNACNYTNAARTTYATGGAYATGMGNCCNAARTCN---------------ACNTCN YTNMGNAAYGAYTGYCCNAARGAYCCNTCNGCNATHGAYYTNTCNAARATGGCNTCNTCN TCNAARTCNTAYAAYYTNACNGAYCCNATHAAYAARGGNTGGYTNGARGARCCNYTNYTN TTYACNAAR---------------------------CCNAARTCNAARGAYAGYCAYAAR AARCAYGAYGAYCAYAARACNMGNTTYCCNCCNGGNAARCARCARGTNTCNYTNAAYMGN GCNACNYTNGAYMGNATHYTNGARGAYCARGARMGNTTYGARGAYCAYYTNMGNMGNMGN TCNCAYCAYCCNACNGGNAARTTYGAYCCNTGGACNYTNATGGARGARATHTCNGARGAR ATHYTNAARGARTGYYTNCARGARGTNTCNGARGARGTNGARAARGTNAGYGARGARATH GCNAAYCARATGTAYAARTCNGARTTYATGGTNACNGGNMGNCCNTCNGARTCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARATHGTNGARAGYCARYTNTTYCARCCNCCNCAYCAYCAYTCNYTNTGYYTNGTN GCNTCNACNYTNATHTAYAAYGCNGCNAARMGNTGYATGTCNGCNGARAARYTNATHGAR AAYYTNACNCAYYTNGCNTCNCARYTNTTYATHAAYTTYCCNGARATHYTNGAYATHYTN GAYGARGAYGGNTAYTCNGCNYTNCAYYTNTCNGTNATGAAYGGNGAYATGAARGTNACN AARATHYTNYTNAARYTNGGNTCNGAYTGYAAYCARAARTCNGARAGYGGNAAYACNGCN YTNTCNGTNGCNATHGCNTAYGGNTAYGAYTAYYTNGTNCCNYTNTTYYTNAAYACNTCN GAYGTNAAYACNYTNGAYMGNGAYCAYGAYACNCCNYTNATGTTYGCNGCNTGGAAYAAR AARCCNAARATHATHTCNGCNYTNATHGAYAGYGGNGCNATHGTNAAYACNAARAAYAAR TAYGGNAGYACNGCNATHTGGAAYGCNGTNTAYCARTCNTCNCCNGAYTGYGTNTCNMGN YTNYTNAGYCAYAAYTCNGCNATGGAYGTNGCNTGYAARGGNACNCAYYTNTTYYTNAAY GARAAYGAYATHAAYCAYAAYGARGARMGNATHACNAARYTNTAYCCNGARTAYAARMGN TCNYTNYTNTGGGTNGCNGTNGAYMGNATHGCNGTNAAYAARGARAGYYTNAARGTNYTN YTNATHYTNYTNGARGCNGGNTAYGAYGTNACNAARGARCAYTGGYTNAARAAY------ ------CCNGTNGAYTGY---CCNAARATHYTNCAYTCNAAYYTNGCNYTNYTNGGNATG YTNCARTTYYTNTAYAARCARCCNCARAAYYTNAARGAYYTNTGYMGNAAYACNYTNMGN AARCAYCAYMGNYTNAGYAAYYTNAGYTTYCAYGARTGGYTNGGNGGNYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TCNTTYTCNTTYYTNGCNYTNATHTGY------ ---------------GCNATHGGNYTNGTNAGYTGYCARTTYGAYACNGAYMGNGARMGN GARYTN------------YTNGARMGNGARMGNGCNGARMGNGARMGNMGNGTNMGNYTN GCNGARGGNTGYTCNGGNAARGTNATGGAYATHTTYTTYYTNATGGAYTCNTCNTCNTCN ATHTAYATHAAYGAYTAYATGTCNCARCAYMGNYTNGTNMGNGAYATHATHAGYAARTTY GAYGTNAGYGTNGARTCNACNMGNGTNGGNATGYTNACNTTYAGYGAYGAYYTNGARMGN CCNGTNATHGGNYTNAAYMGNTAYAGYACNAARAAYGARYTNYTNAAYAGYATHTCNGTN CARATGYTNCCNTAYMGNACNGGNGTNACNAAYACNGAYYTNGCNATHMGNCAYGTNMGN CARYTNAGYGAYTTYMGNCARGAYATHACNAARGTNATGGTNGTNATGACNGAYGGNGGN TCNMGNTCNCCNGGNTCNACNGCNMGNGARGCNGARYTNGCNMGNAAYGCNGGNTTYTAY YTNTTYGTNGTNGGNATHGGNCARTAYATHGARGARMGNGARTGGMGNTCNATHGCNAGY GAYCCNGAYGARAGYTTYGTNTAYAAYATHACNAGYCCNMGNTTYYTNGARGAYGTNAAR TTYTCNYTNCCNCCNMGNGCNTGYGCNYTNCCNCCNATHATHYTNGGNGGNTCNTGYGAY GTNAAYGARATGGCNGARGTNTTYTTYGTNGCNGGNMGNAGYGCNAGYGARMGNGCNATG GAYTTYYTNGARAGYTTYAAYMGNMGNAGYMGNGAYAAYMGNGAYYTNYTNMGNGTNAAY TAYATGGTNGAYGGNTGYGCNCCNATHAAYAAYGTNGGNYTNGTNGARGCNGARCCNTTY YTNTGYGARMGNTTYGAY---CCNMGNACNGGNGAYGTNGTNAAYCCNGTNGGNGTNGTN GARATGYTNACNMGNGTNTCNMGNAGYATHATGAGYGCNMGNGAYACNAAYCARGTNGTN GTNYTNTTYYTNGAYGAYGARACNATGAGYGCNTCNMGNTTYGAYYTNGCNAAYATGGCN MGNAGYYTNGTNAAYYTNGAYGARACNACNGTNGTNGTNGCNGAYYTNGGNATHMGNACN TAYMGNGAYTTYGCNCARMGNYTNGTNACNAGYMGNAAYAAYATHGTNAGYTTYTCNGGN GGNAGYYTNGCNGGNCAR------------------------------------------ ---------------------------------TTYGAYAGYCARCCNGARAGYTCNGGN TAYGCNCAYGAYGAYTTYGARAARGTNGAYGCNCCNGGNGGNGGNTTYAGYCAYGAYGAY ATGACNGCNGCNGCNTCNGGNGCNTAY------GAYGTNGAYCARGAYGCNGARATHTCN ACNACNGCNGAYGTN------ACNGGNGARGARGARGTNGARGCNGAYMGNTTY------ ------GCNGARGAYGTNYTNGGN------CAYCCNTCNGARCCNYTNATHTCNTGGGGN GAYGAR---------------------------------------GAYGARGARACNGCN CARGTNCARCCNTCNGCNCCNGTNCCNGARAGYAAYACNGCNGAYTAYATGCARTCNTTY ---ATGMGNTCN---ATHCCNCCNTCN------AAYACNACNCCNGARCCNAGYYTNTCN TCNTCNAGY---ATHCCNCARACN---CARYTNGAYGARTTYYTNGARCCNAARMGNGAR GARAGY------------GGNGTNGTNGAYAARGAR---------AGYGARAGYAAYCAR GTNTCNGAYCARACNTCN---ACNGTNGARTCNGCNGARGGNTCNTGGYTNAARGGNGTN GAYCCNMGNGARGAYGAYACNGAYGAYACNTTYTTYCARGGNNNNATHGAYYTNATHTAY TGGMGNGAYGTNAARACNACNGGNYTNGTNTTYGGNACNATGYTNGTNGTNYTNYTNTCN YTNGCNATHTTYTCNYTNYTNAGYGTNYTNGCNTAYYTNTCNYTNGCNGTNYTNGTNGTN ACNTTYAGYTTYACNGTNTAYAARAARATHATGGGNGCNGTNCARAARTCNACNGARGGN CAYCCNTTYAARCARYTNATHGAYATGGAYATHACNYTNAGYGARAAYAARYTNAARAGY GTNATHCARAGYATHYTNAARAAYGTNAAYTGYACNGCNAGYGARYTNMGNMGNYTNTTY YTNATHGARGAYATGGTNGAYTCNATHAARTTYGGNYTNYTNYTNTGGGTNYTNACNTAY GTNGGNGCNTGGTTYAAYGGNATGACNYTNATHATHYTNGTNGTNATHTCNATHTTYACN ATGCCNAARGTNTAYGARACNTAYAARGTNCARATHGAYAAYTAYATHTCNYTNGCNAAR GCNCARATHGAYAAYGGNYTNAAYATHGTNCARAGYAARYTNCCNTTYYTNAARAARAAR GARAARGCNCAR------------TTYTCNTGGTTYAGYMGNTAYGGNCCNGGNTTYCAY ATHMGNGGNGARCARGTNCARATHATHACNGARCCNMGNCARTTYTAYGARATHYTNAAR GTNAARACNMGNAARGCNAARMGNMGNGTNACNYTNGCNTCNYTNTAYYTNGGNAAYGGN CARYTNGARAARGARYTNGTNTCNTGYATHAAYGARGCNTGYTGYTCNGTNTCNATHAAY GARTCNYTNGAYYTNGARGTNAAYGTNYTNYTNGAYTTYACNMGNGGNTCNMGNGGNCAR CAYAAYTCNMGNACNATGYTNMGNCCNYTNYTNGARAARTGGCCNAAYGTNAARGTNGCN YTNTAYCAYACNCCNGAYYTNMGNGGNTGGYTNAARMGNATGGTNCCNGARMGNTTYAAY GARACNATHGGNYTNACNCAYYTNAARGTNTAYYTNTTYGAYGAYAGYGTNATHATHAGY GGNGCNAAYYTNAGYAAYGAYTAYTTYACNAAYMGNCARGAYMGNTAYATHYTNTTYAAY GAYTGYCCNCARYTNGCNGAYTTYTTYCAYCAYYTNGTNAARTCNGTNATGTCNTTYTCN YTNCARYTNGAYGTNAAYGAYTCNYTNCAYYTNGCNCCNGAYTGGAAYGTNCAYCCNTTY YTNGAYTCNGAYAAYGGNTTYAAYTTYAARYTNGCNGCNMGNGARAARATHCARCARTGY YTNAAYAGYCAYGTNTCNTCNCARGAY---GARGARGARGGNTAYGARAARATHAAYTAY AAYACNAARGAYGAYTCN---------------------GCNGAYACNGTNATHTAYCCN YTNGTNCARATGGGNCCNTTYGGNGTNCARAAYGAYGARAARGCNACNGTNGARYTNYTN YTNMGNTCNGAYCARMGNGAYYTNATHYTNYTNACNTCNGGNTAYTTYAAYYTNACNGAY CARTAYACNGAYGTNATHGTNGGNGAYGCNGAYTCNAARTTYAAYATHYTNATGGCNTCN CCNAARGCNAAYGGNTTYYTNGGNGCNAARGGNATHGCNGGNGCNGTNCCNTAYTCNTAY ATHTAYYTNGCNCAYCARTTYCAYAAYAARGTNGCNAARGCNGGNCARGCNCAYMGNATH CARATGYTNGARTAYGARMGNGARGGNTGGACNTTYCAYAGYAARGGNYTNTGGTAYTAY YTNAARAAYGARCCNYTNCCNMGNYTNACNYTNATHGGNTCNCCNAAYTTYGGNGTNAAY TCNCARGCNAARGARYTNGAYGGNCARYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MGNGGNTAYCCNGGNCARMGNCCNGARAGYMGNGARACNTAYCARAGYGCNGAY ACNMGNMGNYTNGARGTNCCNTCNTCNCARGCNGARGTNTCNMGNGCNGGNGARAGYGTN ATHCARMGNCCNYTNACNGAYTCNAAYTAYGTNMGNAARAAYTTYGCNGAYAGYGGNCAY GCNATGYTNYTNTCNGCNTTYCARMGNGAYAAYGCNMGNAGYTCNCCNCARACNATHTCN ACNGCNCARTCNYTNCARATGAGYGGNGGNTCNGTNACNGCNGAYMGNYTNATHAAYGCN ATHATHATHCAYTCNATHAAYCARACNTCNCCNGARGAYAARAAYAAYGCNTCNCCNTCN CCNYTNMGNYTNGCNGCNACNCCNACNTCNGGNGTNGAYCARGCNTCNGGNGCNTCNGGN GAYCARMGNCAYACNTCNGCNGARGCNATGGTNCCNGAYGGNGGNGGNMGNCCNGAYYTN ATGGAYCCNATGCARMGNGARATGATGGAYCARMGNAARMGNCARATHGTNGCNGARCAR YTNCARYTNCARGARATGCAYMGNMGNMGNCARCARGARGARMGNMGNCARCARGARGTN TCNTCNTCNCARTCNCARTCNCCNCARCARTCNGTNCCNGARTCNGCNTAYGCNGCNAGY GGNGTNCCNACNGTNGAYAGYAGYGGNTCNAGYACNGARTCNCCNTCNCARAGYGCNGAY TCN------YTNCARCARACNAARATGGGNATGGGNTAYMGNGAYCARGTNGCN------ AGYTCNGGNGAYGGNGAYAARCCNTCNTCNTCNACNCARTCNTCNCCNCCNGARGGNYTN GGNCCNAAYTTYGTNCARTCNTCNGAYGTNGARGAYATHTCNGGNGGN---------GGN GGNGAYTCNGCNYTNTCNCCNTCNTCNAGYYTNCARGCNTCNAAYMGNAARMGNGGNATG GGNMGNGTNMGNGGNMGNCAYGARGAYCCNGGNGGNCCNAGYATHTCNTCNTCNTCN--- ---------TCNGCNCCNAARTCNTCNTCNATHCCNAARTCNTCNGCNTCNTCNACNTCN GCNTCNCARCCNAGYAAYTCNMGNCCNACN---------CCNCAYGCNACNGARGCNGGN GGNMGNGCNTCNCAYAARATGCCNGGNGAYAARTCNGGNAARYTNTCNGCNTAYGAYTTY CCNGAYGAYAGYCCNGAYGARGAYCCNGTNAAYTAYATGGCNYTN---GCNGCNMGNTCN ACNMGNAARTGYCCNGTNGAYAGYTCNGARAAYAAR---ACNACNTGGGTNGGNCCNGAY ACNCARAGYGCNGAYGARGGNAARGGNGARAARAGYGARGCNCARACNATGGARACNTTY ------------------------CCNGAYCCNAARCCNAARTCNMGNTTYGCNAGYMGN GTNAGYAGYAAYGARGCNGAY------ACNGGNATHCCNTCNGTNGAYAGYAGYACNMGN CCNGAYAAR------GCNCARGAYTCNGARGARGTNGAYAGYTCNACNTCNTCNTCNCCN MGNGAYGGNGGNYTNAARATG---------GGNCARGCNTCNGAR--------------- GCNGGNACNTTYTCNCAR------GCNGGNCARTCN------------------------ ---------------------------------------GTNTCNAGYCCNTCNTTYTCN TCNGGNCARCCNGTNGTNTCNAGYATGATHMGNGAYCCNGAYCARACNACNATGTGYTCN MGNGAYCARGARCCNGCNCCNYTNYTNTCNGCNCARTAYGARACNYTNTCNGAYGAYGAY ------GARTCNMGNCCNTCNGARACN---CAYAAYTGYAAYGTNTTYMGNACNTCNACN GTNATHGAYGCNCCNGTNCAYGTNGTNAAYGAYACNTAYCCNYTNTGYCCNTTYAAYAAR CAYAARGARTGGGCNCCNGAYATHGAYGAYGTNTGYGARGTNGARTCNYTNGARGGNAGY ATGGTNATHTAYCAYGTNAARACNCAYAGYATHTCNMGNATHATHTCNCCNMGNAGYTTY GTNGCNGTNGGNGGNCAYGAYAARGAYATHYTNCCNATHYTNMGNTAYGGNGTNAGYGTN GAYTAYCCNAARCCNGTNCARGARGAYGGNATGGTNMGNGGNATHTAYGGNCCNTAYGGN ATHMGNATHAAYGTNAAYCCNGGNAAYCCNGAYCARACNMGNTGYGARGGNATHYTNCAR ATHGAYTTYAARGGNMGNATHCCNMGNAARYTNGTNGAYAGYAGYATHCCNAAYTCNATH GTNAGYTCNCAYGARCAYTAYYTNGARTAYATGMGNAARCAYGGNYTNYTNATGTGGMGN TCNCARACNYTNMGNAARGGNAARCARATHYTNACNGCNACNCARMGNCAYYTNGCNGCN GARGCNGGNGGNGCNGCNTCNACNCCN------CCNCCNCCNCARCCNAARTCNAARGGN TTYGGNGTNGTNAARTTYTTYGGNYTNGGNYTNCCNYTNGCNACNGGNGGNGTNGTNGGN TAYGCNTGGTAYGAYAARGAYTTYMGNAARCARYTNGARGAYAAYGTNCCNTAYTCNAAR GARYTNYTNGARAAYGTNYTNCCNTCNGTNGAR--------------------------- ------GTNAARACNCARAGYGARTCNYTNAARAGYGCNGARAARYTNCARATHCCNGCN CCNATHTTYGARTCNAARCARYTNTCNTCNAARGTNGAYGARTCNGGNAARTCNAAYAAY YTNGCNGTNGARAARGARACNAAYAARAAYGAYAARAARACNGARGCNGARCARATHMGN AAY---AARATGATGGARGARAARTCNGAYAAYGCNGCNYTNGARGTNGTNATHAAYAAR YTNYTNGARTCNGGNCARAAYTGGGTNTCNGARGCNGCNMGNGCNCARATHGAYGTNGCN AARGCNACNATGAGYCAYAGYGCNYTNYTNAARAARGCNATGGAYGARACNTCNAAYATH YTNGAYAARGAYGTNGARTGGGARGCNGTNACNGTNGCNTAYAARGARMGNGARATHGCN GTNGCNMGNGCNAGYGARYTNGTNGAYGARGCNMGNAARAGYATHGARAARYTNAARAAR GTNYTNGAYGARGCNAARGCNAAYAARATHACNATGAARAAYTCNGCNATHTAYCCNGCN ACNAARAARATHGCNGAYTTYACNATGGARATGTCNGCNGCNGGNGCNCARGTNMGNCAR GCNGAYGTNGAYGCNAARGTNATGYTNAARTAYAARGAYYTNGTNGAYAARGGNAARAAR CARTTYCARYTNGARYTNGARAGYYTNYTNCCNGAYTCNAARAARGCNGGNAARAGYMGN AARYTNACNGAYGAYGARYTNAAYGCNYTNGTNGCNCAYGCNCAYMGNMGNATHGARCAR YTNCARAARCARATHGCNGARCAYYTNGCNATGGARMGNAARMGNYTNAAYGTNGCNYTN GAYGCNCARAARGARGARAAYMGNAGYATHACNCARGCNGCNGTNGCNGAYGARMGNGCN MGNYTNYTNACNGARTTYGARYTNGARAARCARAARATHGARATHGARTTYGCNGCNTGG ATGGARGCNGAYGTNMGNAARCARYTNACNMGNCARGCNGCNGCNCAYAGYGAYCAYYTN AARGAYGTNYTNGCNGTNCARGARCARGARATGAAYAARGAYTTYGARMGNAARATGAAY ATHAARYTNYTNGARGARMGNGARAARTTYCARACNGARACNTAYGGNTGGATHTCNMGN YTNAARGGNATHGARGCNGCNGTNGAYGCNMGNGCNGCNAGYGARAARYTNGCNCAYACN GCNCARGAYYTNTGGYTNGCNTGYATHACNYTNAAYTCNACNATHCARTTYGGNAAYGAR GARGARGGNAAYGCNYTNATHCCNYTNCARAAYCARGTNAAYACNATGGTNAAYTCNTCN GAYAARCAYCCNTTYGTNCARACNATHGCNAAYACNATHCCNCARACNGCNYTNGAYMGN GGNATHTAYACNGARAAYAAYYTNMGNGAYMGNTTYGTNAARGTNTCNMGNATHAGYTAY MGNYTNGGNYTNATHCARGARYTNGAYGCNTCNYTNTAYCARTAYYTNGTNTCNTTYYTN CAYTCNTTYYTNACNGTNACNAAYGTNGCNGCNTAYTCNGARAARGAYATGGTNTCNGTN GARGARATGGAYAAYTTYAARYTNGTNTCNAAYGCNCARTAYTGGATGGARAARGGNAAY YTNGAYATHGCNYTNMGNTTYATGTGYCARYTNACNGGNGARTCNMGNMGNGCNGCNGAY GAYTGGATHTCNGARGCNAARYTNYTNYTNGARACNMGNCARGCNGCNCARACNATHYTN ACNTTYGCNTCNGCNACNGGNYTNGCNGCNACNTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MGNGAYGCNAARMGNGCNCAYGAR ATGAARATHCCNTTYAGYGTNGARGARATHGTNGARTCNCCNGTNGARACNTTYAAYGAY ATHYTNACNAARTAYAGYYTNACNGARGAYCARYTNACNYTNATHMGNGAYATHMGNMGN MGNGGNAARAAYAARYTNGCNGCNCARAAYTGYMGNAARMGNAARGTNGGNGTNATHGTN ACNYTNTCNGAYGAYATGACNGARYTNCARAARGTNMGNGAYMGNYTNATGGARGARMGN ACNGCNATGGARMGNGARACNMGNAARATGAARGARAARTTYGGNAAYYTNTAYACNCAY ATHTTYCARTCNYTNMGNGAYGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TTYTTYYTNGTNCCNTTYYTNCCNGARATHTAYATG GGNYTNGAYGAYYTNAARCCNYTNGAYGTNATGTTYAARGGNAARMGNAAYGGNGTNATH ACNGAYGCNACNACNMGNGARGAYGTNGAYGTNTAYAARTAYYTNTAYCCNAAYMGNCAY GCNTTYACNGGNCCNATHAAYTAYATHMGNGCNGGNYTNYTNTAYGGNAGYTCNTCNTGG YTNTCNCARAARGTNACNAARCCNGTNYTNYTNATHTGGGGNTGYMGNGAYYTNGCNYTN GARACNGGNYTNGCNAARTGYTGYAARGAYTAYGCNTAYAAYATGACNATHCAYTAYYTN AARTAYTCNAGYCAYTGGGTNCARATGGAY------------------------------ ------------TCNAAYGTNTGYAAYATHGTNATGTTYTGYAARATHGGNTTYAARGAY ACNTTYAAYATHTCNYTNATGGCNYTNTCNGTNTCNGAYYTNGGNAGYTCNATHATHYTN TTYTGGATGGGNAAYCCNYTNTTYATHTTYTCNGAYGTNCCNTTYGAYACNYTNTCNYTN GTNTAYYTNACNGGNGGNTGGGTNMGNATHTAYTTYACNMGNACNACNAGYTGGYTNACN GCNATGATHTCNYTNGARMGNTGYYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGYTNAAYAARATHACNACNATH TGYMGNTTYATHCCNMGNGTNMGNAAYGCNMGNTCNATG------GGNCAYGGNGTNCCN GCNCAYTTYAARTCNGTNMGNCARATHTGYGARGARAAYAARAGYCAYATGAAYTTYATG CCNATHCCNGARGGNTCNTGGCARGARGCNTAYAAYGCNAARAAYTCNAARTAYAAYATG YTNATGYTNGGNTCNYTNGTNGTNTTYGTNGCNACNGCNGCNATGYTNGTNGCNACNGAY TGYGTNTAYYTNCAYGGNGCNCCNCCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CAYGGNMGNGAYGTNCAYGAYGAYATH MGNGAYMGNATHYTNAAYGGNACNGARMGNACNAARATGGARGCNATHAAYAARYTNGGN CARYTNGGNATHATGACNGCNAARYTNYTNCCNGCNTTYYTNAAYTGYTTYTGYGAYTCN TAYGTNTCNATHMGNTGYGARGTNTGYATHACNTGYGGNAAYYTNCARATHAARGARGAR CARGTNYTNGARMGNYTNGTNCAYYTNGCNACNTTYGAYCCNATHTGGAARGTNAARGCN YTNGCNATHCARGCNYTNGGNAARATHGGNGARGTNACNGARGAYATHAARGAYTGY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGMGNTAYGCNAAYTCNAARAGYTTYGARTTYYTNGARCCN GAYCARATHGAYGARGCNAAYGTNGTNGARCAYYTNTCNTCNAAYTTYCARCAYTAYAAY ACNGGNAARACN------------TGGGAYTGYGCNTGGTCNCCNAAYAAYGCNTAYTTY GCNTGGTCNAGYGGNCAYCAYATHGTNCAYYTNATHCCNTGGGAYAAYGTNYTNCARAAR MGNCAYGAYCCNGARGAYTTYGAYGGNYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CARTAYCARGAYYTNYTNAAYGARGARCCNGARGAY GARGARGGNMGNATHGTNCAYTCNATHATGAARACNACNYTNGGNMGNAARTCNGGNGGN AGYAAYGAYGCNACNTTYAAYTCNAARACNCARACN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TTYAGYATHMGNCCNYTNAARGAR GAYGARTGYGGNCARGTNGTNGCNATGATHGAR--------------------------- ------GARYTNGCNGARTTYGARAARATGGGNGAYCARGTNAAYATHATGCCNGAYGGN YTNMGNAARGAYATHTTYGAYGARCCNCARMGNTGYTGGTGYYTNGTNGCNGARAAYGAR ATGAAYAARGARYTNGGNGTNGTNGCNTAYGCNYTNTAYTAYTTYGCNTAYTCNACNTTY GARMGNACNTAYYTNCAYYTNGARGAYYTNTAYGTNAARCCNGAYTTYMGNMGNAARGGN ATHGGNAARMGNYTNTAYCARGCNTGYACNCARGTNGCNGTNGAYYTNGGNTTYCARMGN GTNGARYTNGGNGTNYTNGGNTGGAAYAARCCNGCNAARGAYTTYTAYGARMGNATHGGN AAYAARGAYATGTCNGARYTNGARGGNTGGCAYAARATGMGNYTNAAYMGNGARCARATG GARAARTTYGTNAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG TCNACNACNGTNTAYTGGGGNGARATHCCNGARATHTCNGAYACNGAYTCNGGNATHGCN GCNYTNGARMGNGARCARATHACNAARCCNAARCCNATGGAYGTNGARGGNCAYYTNYTN CAYCARCCNTCNAAYMGNCAYCAYCCNCCNACNAAYGARGTNYTNTCNAGYGAYCAYTTY AARATGGAYCCNGTNGTNYTNCAYACNATHMGNYTNYTNCARCAYATGAARAARGTNMGN TCNGCNATGGARTCNYTNCARCARGAYATHAARTCNGARACNGARCCNATHGCNATHAAY GTNGGNCCNATHCCNGARTAYGAYGGNCCNCARATHAARGAYMGNTCNCAYCARAARTAY TTYTCNGARGARGARTAYCARAGYGAYTTYGTNAARGGNGTNTCNAARCCNCARCCNCCN ATHGAYGARGCNACNTGYMGNAARYTNYTNMGNMGNTCNACNGCNGCNATHTGYGCNCAR YTNTCNATHGAYACNGCNCCNGARTCNGTNYTNGAYACNYTNACNGAYGTNTGYCARGAR TTYTTYTCNCARTTYACNMGNCAYYTNGGNGTNGCNACNGAYMGNMGNGCNCARCAYGGN AGYAAYGGNTTYCCNGAYTCNATHGARMGNGTNYTNCAYGARATHGGNATGGGNAGYGTN ACNGARYTNCAYACNTTYTAYCARCARMGNGTNYTNGCNTAYCAYAGYMGNGTNGARCAR CARTGYCARTCNTTYATGGCNGARTAYAGYGTNYTNGCNAARCARCCNCAYTCNTCNTCN AARCARGTNTCNACNTCNCCNAAYATGACNGGNGAYACNYTNCARGTNATHMGNATHAAR GARGARCCNAAYACNACNATHCARTTYCCNYTNYTNTAYGAYAARGAYGAYGTNGCNGAR GCNGARCARYTNYTNAAYATHGARAAYATGGGNCCNTTYGARATHGTNGARCAYGARATH CCNACNGGNYTNACNACNGARATGAARGCNAARGGNATGCARGCNAARGGNAGYGCNGGN GARAGYMGNTCNTCNAARATGTCNATHTGGAGYTCNGTNGAYGARTCNAGYGAYAAYCCN GGNAGY------------AGYCAYGAYATHACNGTNACNACNCCNCARTCNGGNATHCCN ACNACNCCNCARGAYGCNAGYGTNCCNACNCCNMGNGAY---AAYTCNACNGAYGAYGGN GCNATHCARGARCCNGGNTCNATHAGYAGYGTNGAYATHTTYTCNCCNACNATHTCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GGNATGGARCCNATGGGN YTNTTYTGGAGYATGAARTCNTCNCCNGGNGAYAARCCNMGNMGNYTNTTYAGYATGAAY GTNTCNMGNCCNTTYGAYATHGARATHTCNYTNCAYTCNAAYTTYATHGAYTTYAAYAAY YTNCCNTGGGARTCNGAYCCNCCNCCNYTNACNTCNTGYAARTTYCARCARMGNTTYATG GAYCCNTCNGTNAARTCNATHCCNGTNMGNGARGAYGGNYTNATHGGNACNYTNTTYYTN CCNGAYGGNGARGGNCCNTTYCCNGCNATHATHGAYGTNTTYGGNATGGCNGGNGTNAGY ACNGAYCAYMGNTCNTCNYTNYTNGCNTCNMGNGGNATHGCNTCNTTYACNATHAAYTAY GTNGGNCARCCNGGNYTNGCNCARTCNATGGARGAYYTNGAYTTYAAYTAYTTYYTNMGN GCNTTYGAYTGGYTNTCNMGNCAYCCNAGYGTNAAYTCNGARTCNYTNGGNGGNYTNGGN AGYTGYATHGGNGCNGCNTAYGTNTCNYTNATHGCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CCNGAYTTYGAYGAYCARATHGTNAAYGTNACNGTNAARGARAARACN ACNGCNGTNYTNCCNTGYTCNGTNATHAAYYTNGGNATHCAYCARATHGTNTGGACNGAY CARTAYTCNACNYTNYTNACNCAYGARGAYMGNMGNATHATHGAYGAYGAYMGNYTNAGY GTNGARMGNCCNTAYAAYMGNGAYTGGAAYYTNCAYATHMGNGAYGTNMGNTAYAGYGAY CARGGNYTNTAYAAYTGYCARATHAAYACNGARCCNATHMGNATHAARATGGTNTAYYTN AAYGTNYTNGTNCCNTCNAARATHYTNGARAAYYTNTCNACNMGNAAYGTNACNCARGAR GGNGARAARGTNACNYTNGTNTGYAAYGCNACNGGN---GAYGARYTNCARAARAARYTN GGNGGNTAYGGNMGNTAYCARGTNATHATHTAYATHYTNYTNGGNATHGTNTAYATGMGN GGNTCNTGGCAYGCNTTYGTNTCNATHTTYCARGGNATHGAYCCNGGNTAYCAYTGYMGN CCNGCNCCNGGNGTNCCNYTNAAYGARTCNGTNCCNTTYAARAAYTCNGAYGGNGAYYTN GARTAYGAYAGYTGYMGNCARTAYGTNAAYTTYTCNYTNGGNAAYCARACNGARGAYTGY ACNMGNGGNTGGGAYTAYATGTAYGARAAYAGYCAYGTNTCNGCNATHATHTCNGARTAY ACNYTNACNTGYGAYMGNAAYTAYYTNATHGARTTYACNTCNACNATGTAYATGGTNGGN TCNACNTGYGGNGTNATHTTYYTNACNCCNYTNACNGARMGNYTNGGNGGNAARAAYGTN ATGYTNGTNTGYYTNTGGYTNCARGCNATHGTNGGNACNATGYTNCCNTGGGCNGGNAGY ATHGTNGTNTTYYTNATHYTNAARTTYTTYATHGGNATHTTYAAYATGACNATHGCNYTN TGYGTNGCNGTNATGATGCAYGARACNTTYGAYGCNACNCAYMGNGARATHCCNGCNATH GGNATHCARTTYTTYTGGGCNGGNGGNATHATHAGYYTNGCNYTNTTYGCNTAYYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATGCAYCCNTAYTAYTAYGTNCARTAYGTNCCNATHCCNYTNAARCARGAYYTNGAR ATGAARGTNAAYTGGGCNGCNTCNCCNAGYACNGCNCCNAARCARGAYACNAGYAARCAY TTYCAYGTNTTYGTNGGNGAYYTNAGYGCNGAYATHGARCARCAYCARYTNMGNGAYGCN TTYGCNGGNTTYGGNGARATHTCNGAYTGYAARATHATHMGNGAYCCNGCNACNATGAAR TCNAARGGNTAYGGNTTYGTNTCNTAYGTNAAYAARGCNGARGCNGARYTNGCNATHTCN GGNATGAAYAAYCARTGGYTNGGNACNMGNCCNATHMGNACNAAYTGGGCNAGYMGNAAR CCNYTNGCNCCNGTNGTNAARGARAAYGCNAARCCNYTNGCNTAYGAYGARGTNTTYAGY CARTCNAGYGCNACNAAYTGYACNGTNTAYTGYGGNGGNGTNACNAAYGGNYTNACNGAR GARYTNATGMGNAARACNTTYTCNCARTAYGGNACNATHCARGARGTNMGNGTNTTYAAR GAYAARGGNTAYGCNTTYATHMGNTTYAGYACNAARGARGCNGCNACNCARGCNATHTGY GCNGTNCAYGGNACNACNATHAAYGAYCARCCNGTNAARTGYTCNTGGGGNAARGARTCN AAYGARACNAAYCARACNAAYCARCARTCNAAYAGYCCNCCNGTNGTNATGGTNCCNTCN CARCARCARCARCCNATHGCNGCNACNCCNGCNACNGCNCCNTAYGGN---CARTTYAAY TAYATGAAYTAYTAYCAYGGNGCNCCNTAYGCNGCNGGNACNCCNACNTAYCARAGYGCN GTNCCNGCNCARGGNCARTTYATHCCNGCNGCN---GGNCARTGGGCN---GGNTAYTCN AAYTAYCARGCNTAYGGNAGYATGAAYGTNCCNGTNGGNCARTAYGCNGGNYTNCARATG CARCCNGGNGGNCARCARCARCARTTYAGYGGNCARGGNCARGGNATGGTNGGNTAYCCN ATGCARCARGGNATGGCNMGNTCNAAYGTNMGNTAYGARGTNYTNCCNTCNGARGARCAR ACNGTNGCNGCNGARCCNGTNGAYATGGCNATGGTNGTNCCNCCNCCNAGYTAYACNGAR AAYGCNGTNATGGARCARGAYGGNGAYAAYCCNGCNTTYGGNCCNGCNAARYTNCCNAAY TAYGTNGAYGCNACNACNYTNCCNACNTAYGARGARGCNGARMGNAGYAARGCNGARCAR GAR------ACNGCNTCNACNAAYAAYGAYTGYGARTCNGGNMGNATGACNTCNATGGAY GGNGTNAAYGARGCNACNATHGGNACNGAYGGNATGTTYATHTGYACNTTYTTYATHTCN TTYYTNTTYAAYTGGYTNGGNTTYYTNYTNTCNYTNTGYYTNTCNAAYACNATHGCNGGN MGNTGYGGNGCNYTNTCNGGNYTNGGNYTNTCNATHGTNAARTGGGTNGTNATHGCNAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYGARAAYMGNYTNTCN TCNTAYYTNATGGAYTCNTCNGAYACNTCNAARACNCCNGTNCCNATGTCNCCNGCNAGY AARYTNCAYCAYYTNYTNATHGARTCNCARGARATGYTNMGNTCNYTNGARAAR---TCN CARGARATGGARATHGAYYTNATHAAYMGNGAYCCNAAYAAYYTNAAYGAYCAYGTNMGN GTNTGYTTYGAYGARGTNATHGGNGARCCNGAYGGNGCNCAYTCNATHCCNTGYGTNTGG ACNTGYTCNTAYAARTGYTTYAAYTGYTGGAARAGYTGYTGYTAYAAYYTNYTNGCNATH YTNTGYGCNATHCCNATHTCNATGTGYTGGGGNTGYGARTTYGCNTAYATHACNTTYACN CAYGTNTGGCAYGTNACNCCNTGYATGMGNGCNTAYATGATHCARTGYGGNTGYATGCAR AARTTYTAYGGNACNTGYYTNCARTGYTGYATGCARCCNTGYTTYGARGCNATGGGNTTY YTNYTNAAYAAYATHMGNGTNACNAAYGTNAGY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYYTNGAYTCNACNCAYAAYACNTCNTTYGTNACN AARAAYAGYTTYACNGAYTTYTCNMGNYTNAGYCARTCNGTNGGNAGYCCNMGNAARGAR TTYACNGGNGTNTCNAGY------------GCNGTNCCNGAYACNAARGARYTNTGYMGN MGNYTNGARGAYAARATHAAYAGYYTNACNMGNATGGGNGGNAAYYTNCARAARGARAAY MGNGARATGGCNAGYYTNATHGAYMGNCARGGNGARAARYTNGAYACNGTNAARCARATH GARAARAARGCNMGNGCNTCNMGN------------------------------TCNAAY TGGAAYCARGARACNAARTCNMGNYTNAAYGARAARATHACNTCNAAYGTNAAYGAYGTN GGNTCNYTNGTNMGNCARYTNATHMGNAGYTCNAARACNAAYGARTTYYTN--------- ------GCNCARGCNGCNAARAAYTTY---GCNTCNCARGARAGYTAYATHCARAAYTCN ACNGARACNATGAARAARATGAAYCAYGTNMGNTCNCARYTNGARTTYCAR--------- ---------------------------------CARTCNGCNATHTCNMGNAGYYTNCAR CAYYTNGAYGARGTNCARGAYCARYTNTCNACNYTNCARCAYCCNTCNGARAARGCNYTN CAYTGGTAYATGGAYAAYATGAAYAARCCNGGNGAYCAYGTNGTNYTNGTNCAYGTNTCN CARTTYCARYTNCAYGTNGGNYTNCCNGGNGTNGCNGTNAAYGTNGARCAYGTNAGYCAR CARGTNCARCARGCNAARGARCARGCNGAYGCNATHACNAGYAARGCNTCNTCNYTNYTN MGNGARMGNTCNATHYTNACNTAYATHGTNATHAARAGYAGYTCNAARCCNCAYGARGCN YTNYTNGARGTNGCNCARGARGARCARGTNAAYCAYATHGTNATGGGNACNMGNGAYYTN GGNACNATHAARMGNGCNYTNGTNGGNAGYGTNAGYACNGARGTNGTNMGNCAYGCNGCN GTNCCNGTNACNATHGTNAAR---------ATGGARMGNYTNTCNYTNCARGGNAARGTN GCNATHATHACNGGNGGNAAYTCNGGNYTNGGNAARGCNACNGTNATHYTNTTYATHMGN MGNGGNGCNAARGTNACNATHGGNGGNMGNAAYGARGCNAARYTNCARGARACNGTNGAR GARTGYAARAARGCNGGNGCNAARGAYGAYCARGTNYTNGCNGTNGCNGGNGAYYTNACN ACNGARAGYTGYMGNCARGARYTNGTNAARAARACNGTNGARTAYTTYGGNCARYTNGAY ATHYTNGTNAAYAAYGCNGGNACNGCNGGNGGNGARCCNYTNMGNGAYATHACNGARTCN GGNYTNGAYTAYYTNATGGAYATHYTNTTYAARGCNCCNATHTTYYTNTCNAARGCNGCN YTNCCNCAYYTNGTNAARACNAARGGNTGYATHGTNAAYGTNTCNTCNGCNATHACNACN GARAAYYTNCCNGGNAAYTTYGCNTAYAAYGTNTCNAARACNGCNATHGAYAARTTYACN GARTTYGCNGCNYTNGARTAYTGYYTNGCNGGNGTNMGNGTNAAYTCNGTNAARCCNGGN ATHGTNCCNACNCARATHTTYAARATHGTNYTN---------------AARGTNGARGAR TTYYTNGARATHCARAARGGNCAYTCNATGYTNGGNMGNAAYGGNGARCCNTGGGARGTN GCNGARATGATHGCNTTYYTNTCNTCNGARGCNGCNAGYTAYGTNACNGCNCARCAYTTY GTNGTNGAYGGNGGNMGNAAYAARCAYTTYCAYCAYGGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHAAYGAYATHGCNMGNGARGCNTTYGTNGAYATHGGNGAR ATGYTNCARACNMGNMGNCAYCARGAYTTYATHGCNAGYTTYGGNTCNTGGCARACNGAY TCNCARTGYGAYCCNGCNTTYACNGAYCCNGARYTNMGNMGNAARYTNGARAARAAYMGN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYGAYGAYGAYGAYGARGAYAARGAYGARAAYGAY ------------------AARTTYAARGCNCCNACNGARYTNYTNATGGARTTYATHGAY TGYYTNATGAARAARGAYTTYCCNAAYGCNAGYAARYTNTGYAARATGATHYTNYTNTAY GARCCNGARAAYGARGARGCNYTNAARTTYCARCCNYTNATHGARGARAARATGGCNYTN GAYGCNGARGCNGCNGCNGARGARGTNGAYAGYGAYGAYGAYGAYGARGAYGAYGARGAR GAYGAYGARGAYGAYATH------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARACNATGGTNYTNGAYTTYYTNAARCARCAYACNCCN AARGGNAARTGYCCNATHGCNGGNAAYTCNGTNGGNTTYGAYMGNCARTTYATHACNAAR TAYATGCCNAARYTNGCNGARCAYYTNCAYTAYMGNATHATHGGNGTNAGYACNATHAAR GARYTNTGYMGNMGNTGGTAYCCNGAYGAYCCNGCNAARAARYTNTCNCAYMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------YTNYTNTCNATGTTY GAYTGGGTNATHGTNCCNYTNGTNAAYCCNGAYGCNTAYGTNTTYACNTTYTCNGAYGCN TTYAAYMGNYTNTGGMGNAARTCNMGNAAYCCNGAR---------TGYTTYGGNGTNGAY YTNAAYMGNAAYTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNGCNYTNAGYMGNCARAARTGYTAYACNTGYCARTAYATHYTNAAYGGNCCNGGNAAR GARTGYATHACNGCNCCNATGAAYTGGACNGGNGGNTAYCCNMGNATGMGNTGYCCNAAY MGNTGYACNACNGTNGCNGARTAYAAYGCNGARACNGGNGARCCNACNTTYTTYYTNMGN AGYTGY---GCNGTNTCNGGNGAYCARAARGAYGGNTGYCARGTNAAYGGNGCNMGNCAY AGYTGYTTYTTYTCNTGYGGNGAYGGNCARAGYTAYTGYAAYGAYAARCCNYTNCCNMGN TCNCCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CARYTNTTYYTNACNGTNGTNGTNCCNYTNGTNATHGGNCARATGATHMGN AAYTAYCARTAYMGNTGGATHCARMGNCARAAYATHCCNTTYCCNACNATHGGNCARTTY YTNATHYTNTTYATHATHTAYACNACNTTYTGYGAYACNTTYTCNMGNACNGAYTTYGAY YTNAGYGTNACNGARTTYATHTTYACNGTNGTNYTNATHTTYAGYATHCARACNGTNTTY ATGGTNTTYYTNYTNTAYTCNAGYTCNTCNAAYTTYTCNTCNAARGAYGCNATHACNATH ATGTAYTGYGGNACNCAYAARTCNYTNACNYTNGGNATHCCNATGATHGARATHATHTTY GARGGNTCNCCNACNATHAGYTTYYTNAGYATHCCNYTNYTNATHTAYAAYCCNGCNCAR ATHGTNYTNGGNGCNYTNTCNATHGGNATHATGCARCAYTGGYTNGARGARCARAARATG AARMGNMGNAARCCNCCNTTYAGYTGGTGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARGTNYTNTCNGARGAY CARCARGARAAYGARAARMGNGTNGAYATHGTNAARCAYGCNTTYCARAAYATHGCNAAR AARTCNGGNGCNGTNYTNCARGCNCARGGNAAYGAYTTYGAYAARMGNYTNAARAARYTN CCNGARACNGGNYTNGGNCAYGCNYTNYTNGARTCNTCNCARGGNYTNAAYATHGAYACN YTNYTNGGNCAYACNTGYCARGTNTGYGGNGARGTNCARGGNAAYYTNGCNAARGARMGN GTNCARTTYGARACNYTNGTNGARCARGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ACNCCN GARGCNGARAARAARAARGAYMGNGAYMGNCCNCCNTCNAARATHGTNATHMGNMGNYTN CCNCCNTCNYTNACNCCNGARAAYTTYYTNGARCARGTNTCNCCNYTNCCNGAYCAYGAY TTYTTYTAYTTYGTNAARGCNGARACNAGYYTNGGNCARAAYGCNTTYTGYMGNGCNTAY GTNAAYTTYYTNAAYGCNGARGAYATHTTYATHTTYMGNGAYAARTTYGAYGGNTAYGTN TTYYTNGAYGAYAARGGNGGNGARTAYCCNGCNGTNGTNGARTTYGCNCCNTTYCAYAAR GTNACNAARAARMGNCARMGNAARGTNGAYTCNAARTGYGGNATHATHGARCARGAYYTN GAYTAYAARAARTTYYTNGAYYTNYTNGCNAAYCCNCCNGARAAYCCNTCNGTNTCNYTN GAYGCNATHGTNGARGARGTNGARGCNAARGARATGMGNYTNGCNAARATGAGYTCNTCN AARMGNAGYACNCCNYTNYTNGARTTYYTNAARMGNMGNAARGARGARAARMGNATGAAY AAYGTNAARYTNMGNGAYGAYMGNMGNMGNGGN---GGNMGNGAYMGNGAYTAYGAYMGN MGNMGNTCNGGNAARGAYGARGGNAAYMGNAARGAYMGNGARMGNYTNATGGARMGNGAY MGNMGNAARGARMGNTCNAARGARYTNGCNMGNGARAARGARMGNGARMGNMGNMGNGAY MGNGAYMGNGAYMGNGAYMGNGGNGGNGGNMGNMGNMGNGAYGGNGGNGARAGYGGNAAR TTYMGNGARGAYCARGARAARTCNAAR--------------------------------- ---CCNATHATGYTNYTNAARAAYACNGARMGNGARAAYCARACNAARGAYGARCAYTCN TAYGAYAGYGCNAAR------------------------GARAAYGTNGAYGARMGNMGN CARGGNAARGARGAYGGNGGN---GGNGAYMGNGGNGGNMGNGARGARAARGGNGGNGGN GGNGGNGAYMGNTTY---MGNGGNGARCARGGNMGNGAYMGNMGNMGNGAYTGGGAYGAY MGNCCNCCNMGNTCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATHYTNCCNGARTCNGGNCCNTAYYTN GTNCAYTCNATGATHGGNTGGTCNGAYTCNGTNATGGCNAARTTYGTNAGYGGNGGNYTN GAYAAYYTNCARATHCCNYTNGTNGARAARACNACNAARGGNGARMGNATHGAYYTNCCN CCNTCNTCNGARGGNAARTGYTTYAARAAYMGNTAYTGYYTNGAYGTNACNATHAGYTTY AGYAAYGGNCARGCNCARACNYTNAGYYTNYTNATHCCNGGNGTNYTNCCNCARACNAAY AARAARTGGGCNTCNTGGAARGCNAARGAYTGGCAYTTYACNTGYGARACNAARYTNTCN AGYTCNYTNTTYTCNGTNGCNGARGAYYTNYTNTAYACNGARGCNTTYTCNAGYYTNCCN ------------------------------------------------------------ ---------------------------------------------TTYTCNGGNTGYTGY GTNGGNTAYTTYAAYCAYMGNTAYTTYYTNGCNATGGTNGTNTAYATGACNYTNGCNGCN TTYTAYTGYAAYATHTAYAAYTGGCARGTNTTYATGGARYTNAARGGNGGNTTYTCNTGG ACNACNATHCCNGGNATHATHGCNCCNCAYATHGGNYTNATGYTNGGNGTNTAYTCNATG TAYGARCCNGARAARATHMGNGGNGGNGGNGARGTNTTYAARTTYCCNTGGACNGCNTAY TCNAARGTNCARCARTTYCCNTTYAARTTYTAYTGGAARCAYGTNMGNYTNTTYMGNTAY TTYTTYTAYTCNACNGCNYTNATHTTYCCNYTNATGGTNAARYTNACNAARGCNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MGNTTYYTNGCNCAR CCNYTNGGNGTNCAYATG------CCNMGNCCNGCNCARCCNTTYATHYTNGCNGCNCCN MGNYTNCCNCCNCCNACNGTNGTNGCNTCNAGYCARACNAGYYTNAAYGGNAGYGCNCCN CCNCCNYTNGTNTCNCCNCCNCAYGARGCNACNGGNYTNATGTAYAAYCCNTAYGCN--- ---GCNGTNGGNAGYATGAGYTCNGCNATHGCNTCNCCNGTNGAYCCNTAYGGNYTN--- ------------------------------------------------------------ ------------------------------ATGGCNGAYACNYTNCARYTNYTNAARTGY GGNGTNMGNTTYTCNCCNCCNACNYTNGTNYTNACNTAYAARGAYTGGAARTCNGGNAAR ATGMGNMGNMGNTCNATGCCNYTNMGNAAYTTYAAYAARAAYTCNGGNATHGARMGNGTN TGYGARGAYYTNAARGARAAYCCNMGNCAYGCNAARTAYGTNMGNYTNATHTCNCCNYTN CARYTNCARMGNYTNYTNACNATHACNAARGAYAARATHAGYGGNYTNAGYYTNGARGCN AGYATHGCNMGNAAYAAYGARATGGARACNYTNAARCCNGARGARAAYYTNAAYAARGTN GAYGARGARACNYTNAARMGNAARAARYTNGTNATGAAYTCNTCNTTYGARAARAAYCAR AARAARYTNGGNGAYCCNGAYTTYGARTAYAAYGTNGARGTNGAYTTYGARGGNGGNACN ATHGARACNAGYGGNTGGGAYTCNGARGAYTCNGAYATGGAYTTY >kerguelenensis ------------------------------------------------------------ ---------YTNTAYMGNATGGARYTNYTNACNGAYGCNYTNCARGAYTAYYTNCCNGAR CARCARYTNYTNGAYAGYMGNAGYGTNGAYGCNGGN------GAYTAYTGG--------- ------------------------------CCNAGYGAYGTNCARGARGCNATHTAYAAY GAYCCNTTYTAYAGYGGNGCNCAYCARMGNGAYGARGARCAYYTNGARCAYAGYGAYYTN CAYGGNTTYCARTCNGTNCARGGNGGNACNGCNGARGTNAARCCNAAYCARAARCARGTN AARTCNGAYAARCARYTNCCNGCNTAYTGYAAYCCNCCNAAYCCNTGYCCNYTNGGNAAR AAYGARAARGAYAAYTGYGTNGARAAYTTYGAYAAYTCNGCNGARAAYAAYAARMGNYTN YTNYTNCARCARGAYTGYCCNTGYGAYACNGARCAYATGTTYACNTGYCCNGCNGGNAGY GARACNGTNAGYTCNAARAGYCARGGN---------GAYACNYTNAGYAARGTNATHGAY GARYTNGARAARATGGGNAAYGGNGAYTTYGGNATGGGNAAYAAYCCNTAYYTNACNACN AAYAARMGNMGNYTNAARGTNGTNGCNAARAARTCNCCNCAYATGATHMGNAARMGNTCN GARAAYTCNGAYCAYGGNAAYCCNTAYYTNATHGGNGARMGNATGAGYMGNGCNGCNAAR AARGAYCAYYTNGARGCNYTNGAYYTNYTNTCNATHGGNGCNGCNYTNCARCAYCAYATG YTNTAYTAYGTNTCNACNYTNATHACNGTNYTNATHTCNYTNGARMGNTCNYTNTGYATH GTNATHCCNYTNAARGTNAARCAYGTNATGACNCCNTTYMGNTCNAARTGYATHATHGCN GCNATHTTYGTNCCNAAYATHTCNTGYTGYYTNCCNYTNTTYGCNACNCAYMGNYTNAGY TGGCAYTTYGTNCCNACNATGYTNGTNGCNACNTTYATGATGTAYMGNGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CARGTNTTYCCNAGYMGNTTYAAYAAYGARCAYAARAARTAYATHGCNGCN MGNGAYCARATGMGNMGNAAYCARCARATGAARATHACNGARYTNATGCARGARTGGCAR GCNGCNMGNGAYMGNGTNGARGARGTNMGNAARAAYGAYGARAARGCNGCNGAYAARYTN AGYAARGARATHGCNGARMGNTTYCARMGNYTNTAYGCNTCNTAYGARCARGARGAYGCN GCNGARAARCARCARYTNGTNGCNYTNCAYCARCARCAYGTNCARGCNATGYTNAAYGAR CAYAARMGNAAYGCNATGGAYAARTAYATGAARTCNYTNCARAARGGNGAYGTNAGYMGN ATHGGNAARTAYYTNMGNACNTAYATHAARGCNGARGARAARGAYMGNATGCAYACNGTN AAYCAYTTYCARCAYGTNAARTAYAGYAAYCCNMGNGARGCNYTNMGNATHCAYCCNCAY ATHGTNAAYCAYYTNCARYTNAGYGARCARMGNATHGAYCARGCNYTNGAYATGYTNACN MGNTTYCCNGAYATHAAYAGYAARATHMGNCCNGAYATHGARTAYTTYATGAARMGNTTY GAYGCNGTNGCNGCNAGYATHMGNAAYGTNGTNYTNCCNGTNCCNCARYTNGARGARGAR TCNACNACNGARGARCARGAYAGYAGYAAR---YTNGAYYTNAGYAAYGARATHYTNCCN AAYATHGTNGAYGARYTNAAYAAYGGNYTNAAYATHGAYGGNAGYGAYGAR--------- ------------------------------------------------------------ ------------------------------GAYTCNMGNGARGAYGARCAYGAYTAYGAR MGNAAYAAYAARTTYGTNGCNAAYCARATGGAYAAYTCNCAYGGNGTNCARCARACNYTN GCNAARTCNCAYACNTCNAAYAGYCARGTNGCNAGYACNGTNGGNATHGCNYTNGGNAGY GTNTCNGTNTTYGTNATHATHGTNGTNGCNGTNGTNATGYTNMGNMGNAARAAYAAYAGY CARACNGTNTCN---GGNTAYGTNGARGTNGAYCCNTCNGCNACNCCNGARGARMGNCAY YTNGCNAAYATGCARATGAAYGGNTAYGARAAYCCNACNTAYAARTAYTTYGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GAYTAYTTYAAYGTNATGYTNGGN ACNCARYTNYTNTAYAARTTYGARMGNCCNCARTAYGGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------MGNYTNYTNMGNAARYTNTTY ATHAAYTAYGAYCCNAAYGTNMGNCCNGTNCAYAAYTCNTCNCARACNGTNGAYGTNTTY TTYGGNTTYTCNYTNATHCARATHATGGAYATGGAYGARAARAAYCARATHYTNACNATH AAYGCNTGGYTNGARTCNGARTGGCARGAYGARMGNATHMGNTGGAAYCCNGAYGAYTAY AAYGGNYTNCARGTNTTYMGNATHAGYTCNACNAARGTNTGGMGNCCNGAYATHGTNYTN TAYAAYAAYGCNGAYGAYTAYACNTCNGGNTTYATGCCNTGYAAYGCNATGYTNCAYTAY GAYGGNACNGTNTTYTGGTCNCCNCCNGTNAARYTNMGNAGYTCNTGYAARGTNGAYATH ACNTAYTTYCCNTAYGAYAGYCARGARTGYMGNYTNAARTTYGGNTCNTGGACNTAYGAY AARGCNCARGTNGAYYTNATHAAYAARACNGCNGTNGCNGAYGTNAGYAAYTTYYTNACN AAYGGNGARTGGACNATHACNAARCAYGAYATHGTNMGNCAYGARGTNGTNTAYCCNATH AGYGAYGCNGTNTAYCCNGAYGTNACNATHAARATHCARATHCAYMGNMGNATHYTNTAY TAYGTNYTNAAYATHYTNTTYCCNTGYTTYTGGYTNAAYNNNYTNAGYGTNYTNNNNTTY TGYYTNCCNGTNGARGCNGGNGARAARATHACNYTNAGYATHACNGTNYTNYTNTCNTAY TCNGTNTTYATGYTNYTNGTNGCNGARAGYATGCCNCCNACNTCNGARGCNGTNCCNYTN ATHGARATHTAYYTNACNYTNTCNATGAGYGTNGCNTCNATHTCNGTNATHYTNACNGTN YTNGTNGARAARYTNCAYTTYTGYGCNCCNGAYCARTCNCCNGTNCCNMGNTGGGTNAAR TTYATHGTNYTNGGNGTNYTNAGYMGNYTNGTNTGYMGNTGYTGGGARYTNGTNGCNACN AARGTNATHMGNAAYGTNAARTAYTAYAGYTGYTGYCCNCARCCNTTYCCNGAYGTNACN TTYTAYGTNCARATHMGNMGNMGNGTNYTNTAYTAYTTYYTNAAYGTNATHATHCCNTGY ATGYTNYTNTCNAGYYTNTGGYTNACNGGNTTYYTNYTNCCNCCNGGNTCNGGNGARAAR GTNACNYTNGGNYTNCCNGTNYTNYTNGCN------------------------------ ---------------------------YTNGGNTCNGARGCNAARTGGCARTTYGTNGAY ------------------------------------------------------------ ---------GTNTAYGGNYTNGAYGARGAYATGYTNGCNATHGTNCCNAARCCNGTNATH GCNGTNACNYTNYTNTAYCCNCARACNGARAARACNAAR------TCNGCNGAYTTYGGN GARGTNCARAARACNTAYCCNAAYGARYTNTAYTAYACNAARCARACNATHCAYAAYGCN TGYGGNACNGTNGCNATHGTNCAYGCNYTNGCNAAYAAYGARGGNACNGTNAGYTTYGAY AARAGYAARCAYTTYGTNAARTTYYTNGARGAYTCNMGNAAYYTNAGYCCNGARGGNMGN GCNCARTTYYTNGARAAYGAYGARAARATGGGNGCNGCNCAYGARGARAGYGCNCARGAR GGNGAYACNGARGCNCCNMGNMGNGARGAYGARAAYTTYCCNCAYTTYATHACNTTYGTN CAYAARGAYGGNATHYTNTAYGARYTNGAYGGNMGNAARGAYGGNCCNATHTCNCAYGGN GGNACNACNCCNGARACNYTNYTNGARGAYGTNGTNGTNGTNGTNAARAARTTYATGGAR MGNGAYCCNTAYYTNAAYGCNMGNGARAARYTNATHGARGARGARCARGGNMGNMGNYTN GGNGGNACNGTNAARATGACNGCNGARGARACNACNYTNAAYGCNCAYATHYTNCARYTN AARAARGCNYTNATHGARGAYAGYMGNYTNAAYGGNTCNYTNTTYCCNGCNGCNATHAGY TTYTAYAARGCNAARCCNATGATHAARAAYTCNCCNYTNYTNCARYTNATHCARAARATG CCNAARGGNGCNGCNYTNCAYGTNCAYGAYATGGCNATHGCNAGYYTNGAYTGGYTNATH GTNAAYGCNACNTAYMGNGAYCAYTGYTAYATGTGYGTNGAYAARCARTCNGGNATHAAR TTYMGNTTYTTYCARACNCCNCCNTCNAAYCCNGAYTGYCCNTGGAARYTNGTNAARACN GARMGNGARAARTCNGGNAAYCCNCCNCARTTYGAYYTNCAYYTNAARMGNAAYATHAGY YTNYTNGCNACNGAYCCN---TAYGAYTAYCCNGAYATHAGYAARGTNTGGGARMGNTTY GGNACNTAYTTYGAYCARYTNCARGGNYTNATHATGTAYMGNCCNGTNTTYCCNGAYTAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TAYGARCARATGGTNGCNYTNATGMGNGCNGTNAAYGAYGCNTGYCCNGARATH ACNMGNYTNTAYAAYYTNAGYGARCCNTCNGTNCARAAYMGNAAYYTNACNGTNYTNGAR ATHACNGAYAAYCCNGGNATHCAYGARCCNGGNGARCCNGARTTYAARTAYGTNAGYAGY ATGCAYGGNAAYGARGTNGTNGGNAARGARATGYTNYTNGGNYTNATGGTNACNYTNTGY ACNGAYTAYATHAAYGGNAAYCCNATGGCNMGNTTYATHGTNGAYAAYACNMGNGTNCAY ATHYTNCCNTCNATGAAYCCNGAYGGNTGGCARAARGCNTAYGARGARTTYAARACNAAY GGNTCNGTNGGNTGGYTNACNGGNMGNTCNAAYGCNAAYGAYGTNGAYYTNAAYMGNAAY TTYCCNGAYYTNAAYGAYAARATHTAYGARAAYGARMGNGARCAYAARGGNMGNAAYAAY CAYYTNGTNAARGTNGARAARGCNATHGCNAGYGAYCCNTCNYTNCARCCNGARACNMGN GCNGTNATGMGNTGGYTNGCNGARATHGGNTTYGTNYTNTCNGCNAAYYTNCAYGGNGGN GAYYTNGTNGCNAAYTAYCCNTAYGAYGARACNMGNTCNGGNAARACNCARGARTAYACN GCNTGYCCNGAYGAYACNACNTTYMGNTAYYTNGCNTCNTCNTAYGCNTTYTTYCAYCCN AARATGGCNGAYCCNAAYMGNGCNCCNTGYAAYGGNGAYGAYACNACNAARCARATHACN AAYGGNGGNGARTGGTAYTCNGTNAGYAARGGNATGCARGAYTAYAAYTAYYTNAAYACN AAYTGYTTYGARATHACNYTNGARYTNGGNTGYGARAARTTYCCNCCNGAYTAYAARYTN GCNGGNYTNTGGAARGAYAAYAARGAYGCNYTNATHAAYTAYATHYTNCARAGYCAYATH GGNGTNAARGGNTTYGTNAARTCNAARGAYGGNAARCCNATHGCNAAYGCNGARATHAAR GTNACNGAYYTNGCNACNGGNTTYCCNATHGAYCAYGAYATHYTNTCNYTNGARGAYGGN GAYTAYTAYMGNYTNYTNGCNAAYGGNAAYTAYATHATHTCNGTNTCNGCNAAYGGNTCN CAYCCNGCNTAYMGNTGYGTNCAYGTNGARAAYCARATHMGNGARGAYGAYYTNTCN--- ACNYTNACNCCNGCNCCNCARYTNAAYTTYGTNYTNACNCCNAARGAYGAYCCNGTNCCN GAYACNTGGGCNACNGAYGARGARTGYMGNYTNATH------GARGARCARATGAARCCN ATHAARGARCARAARGARTTYYTNGTNGCNGTNYTNAAYTAYATHGCNCCNCARTAYAAR TGGTCNGTNACNGCNMGNGGNGCNACNGTNYTNGAYYTNAGYCAYTTYYTNTGGGARGAR YTNAARCARATGGGNGARGARGAYATGMGNAARYTNYTNAARAARATGCCNAARGAYGCN CARCARYTNYTNTAYGAYATHATHATGGCNGARATHATHCAYAARYTNTTYGGNCARAAR CAYAGYAARCAYTCNGAYCARGCNAGYAARGCNGTNGAYGCNGARGGNTAYAGYAARCAR CARCAYGARTTYTTYAARGARTTYYTNGCN------------------------------ ------------------------------------------------------------ ---------------------------------------------CCNATHCAYTGYTGG GTNCCNGCNGARTAYAARAARAARCAYTTYCARAARTAYTCNGAYAGYTTYTGYTGGATH CAYCCNATGTAYAAYATHCCNTTYGAYGAYCCNATHCCNTTYAARGCNGARGARMGNTGG TAYAAYGAYATHAGYTTYTAYMGNTGGGTNACNATHGTNTTYYTNATHCARGCNYTNYTN TTYAARYTNCCNAAYATHATHTGGGARCARATGAARATHTTYTCNGGNYTNAAYGTNACN AARATHGTNCARATGTGYATGGAYACNTCNATGYTNACNCARGARAARMGNGAYGARAAR ATGGGNCAYGTNGCNATHTTYATHGAYMGNTGGYTNMGNACNTAYACNATHCAYAARTAY GGNGCNATHAAYMGNTTYMGNGAYAARTTYGCNGGNATHGTNTTYTGYATHGGNAARCAY CARGGNACNTAYYTNACNGGNYTNTAYGTNTTYGTNAARYTNYTNTAYTTYGCNAAYTCN ATHGGNCARTTYTTYYTNYTNTCNGCNTTYYTNGAYATGGAYTTYTGGGGNTTYGGNTTY MGNGCNATGAARGARYTNAAYMGNGCNGGNMGNTGGCARGAYCAYTAYTAYTTYCCNMGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGARATGCCNACNCARYTNYTNYTNTCNYTNYTNGTNGCNYTNGTNGTNGTNGGNGTN GTNAGYGGNATGCCNGCNAGY---CCNCAYGAYGTNYTNCARGARACNTCNGGNATGGCN GTNGAYAARMGNCCNAARTAYATGGAYACNMGNMGNGAYYTNGAYGTNTTYAARGAYYTN GTNYTNATGAGYATHCARGARYTNGTNGAYGARGARMGNYTNAAYCCNGCNGTNYTNCCN GARGAR------GAY---------YTNAARTCNGTNGARAARMGNMGNTAYATGGGNATH TGYATGMGNMGNCARTAYAAYAGYTTYATHCCNGTNCCNTGYYTNMGNAGYGGNMGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GGNTAYGTNAARGAYYTN YTNGAYGARYTNGCNAARGARGTNAARTTYACNTAYAAYTTYATGCARGCNAGYGAYGAY ACNTAYGGN---MGNCAYGAYCCNGAYTGGAARGGNATHATHGGNGAYGTNCARAAYGGN GTNGCNCARATHGGNGGNGCNYTNACNAAYACNATHCARMGNGARCARGTNGTNGAYTTY ACNAGYGAYTTYATGAARACNTCNGTNGCNYTNYTNGTNAARAARCCNAARTTYGARCAY TTYGGNYTNGGNTAYYTNGTNMGNCCNTTYTCNCCNGAYTAYTGGATHATGGTNYTNGTN YTNATHYTNYTNATHGGNATHYTNTTYTTYYTNATHGGNAARTTYAGYCCNTAYGARTGG GGNAAYGTNGCNGCNGARAARGAYCCNMGNGGNGCNMGNAAYAGYTTYTCNYTNMGNAAY AGYTAYYTNTTYGTNYTNAGYGCNATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNGCNGGNTCNACNTGYGCNGTN TTYTAYACNAARACNTCNGARACNCAYTAYCCNMGNATHGGNMGNMGNAGYTTYTAYACN CARGGNTCNGGNAAYCARTAYCCNMGNATHGGNMGNMGNGAYGTNAGYYTNTAYGAYCAR GGNGARTTYACNGAYTTYCCNAAYGARGCN------------------------------ ---------AARMGNGGNATHTTYACNAAR---GGNMGNAGYTCNTTYCCNMGNGTNGGN MGN------------------------GGNCARGARTAYYTNTCNCARAGYCARGARATG ATHGTNCCNTCNGARAARACN---GARYTNGGN---YTNGGNGARGARYTNGGNAAYTCN GTNATGGARGARTCNGAYTCNGAYATGCCNYTNCCNGTN---GARYTNTGGTTYATHGCN TTYGAYTCNAAYGGNGAYGGNCARYTNTCNAARACNGARTTYATGACNGGNGTNAARAAR YTNTGGCAYMGNAARGCNYTNTGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------YTNYTNYTNYTNYTN YTNYTNYTNGCN------GTNGGNGCNTCNYTNGCNAAYTTYGARCAYACNTGYMGNYTN GGNGARAAYACNCCNCAYCCNCARGGNATHTGYGGNAGYMGNYTNCCNTCNATGGTNGAY ATGGTNTGYTCNMGNMGNCARACNMGNAARYTNCAYATHTCNAARMGNGARGCNTCNMGN GAYACN------GTNGGNGGNCAR---YTNAARGAYATHATGYTNAAYMGNMGNGARGCN TTYTCNTAYYTNCARAARMGNGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTNTTYTCNGGNMGNGTNACN ATHACNGCNMGNGTNGARNNNNNNACNGAYTTYGTNGTNTTYCAYGGNAARGAYATHAAY ATHACNTCNYTNMGNGTNACNGTNCCNGGNGGNGGNGGNCCNGAYGTNMGNATHATGAAR CAYYTNGARTAYAARMGNGCNGARCARCAYTAYGTNMGNTTYTAYGARAGYYTNAGYGTN GGNMGNMGNGTNAGYGTNCAYATHAGYTTYACNGCNCARYTNYTNGGNAARYTNGARGGN TTYTAYAARAGYTCNTAYACNGTNAAYGGNGARCCNMGNGARATGGCNAGYACNCAYTTY GARGCNACNGCNGCNMGNGARGCNTTYCCNTGYTTYGAYGARCCNGCNATGAARGCNAAY TTYAGYYTNMGNATGGTNMGNGARAARMGNCAYATHGCNYTNTTYAAYACNCCNYTNAAR AARACNAGYGTNGTNGAY------------------GARTTYGARACNAGYGTNMGNATG AGYACNTAYYTNGTNGCNTTYGTNATHTGYGAYTTYGCNAGYAARGARAARACNACNACN AGYGGNGTNAARGTNMGNGTNTTYACNCCNAGYGAYATGATHGAYCARGCNGAYTAYGCN YTNAAYGCNGCNGTNAGYATHYTNAAYAARTAYGARGARTTYTTYGGNGTNMGNTAYCCN YTNCCNAARCARGAYYTNATHGCNATHCCNAAYTTYGCNGCNGGNGCNATGGARAAYTGG GGNYTNATHACNTAYMGNYTNACNTCNYTNYTNTAYGAYCCNAARGTNGCNACNGCNGGN CARAARCARTGGGTNGTNATGGTNGTNGCNCAYGARYTNGCNCAYCARTGGTTYGGNAAY YTNGTNACNATGAGYTGGTGGAAYGAYYTNTGGYTNAAYGARGGNTTYGCNACNTTYGTN GARTAYATHGGNGCNGAYTAYGTNGAYCCNGARYTNCAYATHAAYGAYATGTTYGTNCCN GAYTCNTTYCAYAGYGCNYTNAAYYTNGAYGCNTTYGGNTCNTCNCAYCCNATHCARGCN ACNGTNAAYGAYCCNGCNGARATHAAYGARATHTTYGAYTCNATHTCNTAYTCNAARGGN GCNTCNATHATHMGNATGYTNCARGGNGTNYTNGGNGARGCNAARTTYMGNYTNGGNYTN ACNAGYTAYYTNAARGARCAYGCNTTYGCNAAYGCNGTNACNAARGAYYTNTGGGAYTCN ATGCARGARGTNGGNAAYGGNAGYATHACNGTNTCNAAYATGATGGAYACNTGGACNAAR CARAARGGNTAYCCNGTNGTNATGGTNACNMGNAAYGGNAGYAGYATHACNYTNACNCAR ACNMGNTTYYTNYTNGGNAAYAGY---------ACNGAYGARAARGCNTCNGCNTAYAAR TTYAARTGGATHGTNCCNTTYACNTAYTCNACNCCNGAYTCNCAY---AAYGCNCCNATH GTNTGGATGAAYATGGAYTCNGCNGCNGTNTCNGTNGCNAGYAGYGCNACNTGGGTNAAR GGNAAYMGNGAYTGYGTNGGNTAYTAYMGNGTNAAYTAYGAYCCNGCNAAYTGGGTNGCN YTNACNGARCARTTYAAYACNAAYCAYAGYGTNTTYTCNGAYAAYGAYMGNGCNTGYYTN ATHGAYGAYGCNTTYTCNYTNGTNMGNACNGAYGGNYTNGAYYTNGARAARGCNATGAAY YTNACNMGNTAYATGAARGARGARAARGCNTAYGGNGTNTGGAARACNGTNATGTCNCAY TTYGGNTTYATHMGNGAYMGNATHGGNMGNGCNGARCCNATHGARAARTTYAARGAYTAY GTNYTNTCNYTNATHGARGAYAARGTNAAYGARYTNGGNTGGGARGAYAARGGNTCNCAY YTNGAYMGNAARYTNMGNGARYTNYTNATHTCNTGGGCNATHTTYYTNGAYCAYCARCCN ACNGTNGAYCARGCNGTNCARGAYTTYAARMGNTGGAARAAYGAYCCNAAYGCNAARATH TCNCARMGNGGN---YTNGTNTAYCARGCNGGNGTNMGNTAYGGNACNAARAARGARTGG GARYTNGTNTAYGARMGNTAYCAYACNAGYNNNNNNNNNTCNGAYCARAARYTNYTNYTN AAYGCNYTNTCNAGYGCNMGNGAYGCNGARYTNYTNTAYMGNYTNYTNCARTAYAGYYTN GAYAGYAARAARATHAARTCNCARGAYACNGAYTCNATHATHACNCAYGTNGCNGGNTCN CCNGARGGNCARYTNYTNGCNTGGCAYTTYGTNMGNAAYAAYTGGGAYACNYTNYTNAAR MGNTAYGGNACNACNTCNTTYATHYTNGCNACNATHGTNAARGGNACNACNTCNCCNTTY AAYTCNCARATHGAYTAYGAYGARGTNAARGCNTTYTTYGCNAAYCAYGARCAYGGNAGY GCNCARATGGCNATHTCNCARACNYTNGARATHATHGCNTCNCAYGTNGCNTGGYTNAGY AARAAYYTNGAYAARYTNATHGARTGGYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYTTYACNCCNAAYTAYTTYCARCCNAAYATHGGNGGN CARGGNTCNATGAGYAARMGNGGN------AGYCARCARGGNMGNMGNGGNGGN---AAY GARCCN---GARMGNAARGTNATHACNAGYATGTCNYTNCARAAYGAYGCNCARYTNYTN CAYMGNGCNGARAARMGNTGGATGCCNAARMGNGAYGARGAYAAYCCNGARAGYAARAAR ACNGARYTNYTNTTYMGNGARGTNMGNGCNATHYTNAAYAARYTNACNCCNCARAAYTTY GAYAARYTNTCNAARAARATHTTYAGYYTNCARATHGAYACNCAYGARMGNYTNCARGGN GTNGCNAAYYTNGTNTTYGARAARGTNGTNATGGARCCNGTNTTYAGYGTNGGNTAYGCN AAYYTNTGYAARACNATGGGNCARYTNAARGTNGARCCNGGN------AARGAYCARACN TCNAAYCARTGYACNTTYMGNGTNATHATGYTNACNAARTGYCARCARGARTTYGARTCN GAYAARAAYATHYTNAARGAYAAYYTNGARGARMGNAARAARAARATHGARCARGARATH TCNGAYGARACN---GARMGNGCNMGNAARATHGARGARGARGARTAYAGYTTYGCNATG MGNMGNAARAARGCNTTYGGNAAYATHATHTTYATHGGNGARYTNTTYAARYTNMGNATG YTNACNGARAAYATHATGCAYGAYTGYYTNTTYMGNYTNYTNMGNAGYMGNGAYTCNGAY GCNYTNGARTCNGTNTAYAARYTNATHCAYACNGTNNNNNNNNNNYTNNNNACNGARAAR GCNAARGCNMGNATGGAYGAYTAYTTYTCNMGNATHTCNAARYTNAGYGAYGAYAARGAY TCNMGNATHMGNTGYYTNYTNAARGAYTGYATGGAYYTNMGNAARAAYAAYTGGGTNAGY MGNMGNCARGAYAAYACNCCNAARACNATHGAYCARATHCAYAARGARTAYGCNACNGAR CARGCNMGNAAYCARYTNATHAGYAGYCARCCNYTNCCNCCNMGNATGGCNAAYCARGAR ---------MGNMGNGGNAGYMGNCARMGNGGNAGYTCN---AAYCCNCARGAYGAYGGN TGGAAYACNGTNGGNTCN---AARTCNATHMGN---ATHGAYGCNTCNAARATGAARYTN TCNAAR---ACNGTNGTNGAYGAYAAYATHCARYTNGGNCCNGGNGGNGGNGTNAGYAAR TTYTCNGCNTGGGGNMGNGGNAGYCARGGNGGNGGNTCNMGNGCNTCNCARGARGAYMGN CCNACNACNCCNGGNAAYMGNTTYTCNGCNYTNMGNTCNGARGARGAYTAYMGNMGNTAY CARMGNAGYCCNAAYMGNGARAGYAGYGGNGGNMGN------ATGMGNGGNGGNCARGGN GCNGGNTTYGGNMGNGGNAARATGGTNAGYMGNTCNAGYCAYGARGGNGARMGNAARGAR YTNYTNGCNAGYGCNMGNTCNATHGTNGGNGGNMGNGCNCCNTCNGGNAGYMGNGARAAY AGYMGNTCNMGNGARCCNACN---------------YTNMGNGGNTCNMGNGARGGNGAR ---------GCNMGNGAYCCNMGNGCNMGNGAYMGNGAYTCNGAYTTYAARACNCCNGCN CCNGTNTCNAGYGCNGTNGARCARATGMGNCCNAAYGAYATHGARAARAARATHCAYGCN ATHATGGARGARTAYYTNCAYYTNCAYGAYATHAARGARGCNGTNCARTGYGTNGARGAR YTNCARGGNCARAAYYTNYTNTCNATGGTNATHTCNGTNGGNATGAAYGARGTNYTNGAR MGNTCNACNCARGCNMGNCAYYTNACNGGNGTNYTNCAYCAYGARYTNGTNAGYMGNAAY ATHATHTCNYTNGAYGCNTAYATHACNGCNYTNAARGAYGTNYTNATGGTNGCNGARGAY YTNGTNATHGAYATHCCNAARGTNTGGGARTAYTGYGCNGARYTNYTNGTNCCNATGGCN CARGAYGGNACNYTNCCNYTNAGYTTYYTNCAYACNGTNTCNCARAAYTTYATGGAYTCN GGNYTNGTNAARAAYYTNGTNTCNGARYTNYTNYTNCARYTNGCNCARAARCARGGNCAR TCNAARGTNAARGARYTNTGGCARGCNTCNAARYTNGARYTNTCNATGTTYGTNGAYCCN GCNAARGTNGAYCARTTYGTNAARGAYMGNAARYTNGAYTTYYTN--------------- ---GTNGGNTCNGCNTCNCARCCNCARTCNTCNGCNATHGAYTTYGCNAARTTYACNGAY GAYGTNACNGCNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CCNGCNCCN AAR---TCNMGNAARMGNAARGCNGGNAGYAGY---GAYGARGTNCAYACNAAYYTNTTY MGNATHCCNGCNGGN---------------GTNAGYGTNACNACNYTN------------ ---------------GARACNGAYCAYGAYTAYACNGCNAARMGNCAR------------ ------------------------------------AARAARAAYCCNGCNTCN------ ------GGNAAYTCNTCNGCNGCNAAYGCNGARGAYMGNGTNACNTCNACNACN------ ---------AAYGAYTCNGAYYTNGTNGTNGAYAARGTNGCNGARMGNMGNATHAARAAY AAYATHGCNTCNAARMGNTCNMGNGARCARMGNAARCARAARTTYGTNAGYATGGAYGAY GARGCNCARAARYTNATHACNGARAAYGARCARYTNAGYCARAARATHATHGCNYTNGAR AARYTNGCNAARGARATGAARGCNATHYTNATHGCNAARATGGCNGGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MGNTCNGTN ACNGGNTCNGGNGCNGTNAGYGARGGNCCNGCNAARGARGAYACNGAYTCNGAYTCNGGN ---AARYTNAAYMGNACNYTNGARGARTCNGCNMGNGARTAYCARGCNAARCAYGAYYTN AARCCNGAYYTNAARGARGTNGARMGNGTNACNGGNGARGARGARGARTCNAAYGTNYTN CARGCNAAYGCNAARYTNTTYYTNTTYGAYAARGARAAYCARTCNTGGYTNGARMGNGGN MGNGGNACNATHMGNYTNAAYGAYYTNTCNTCNGAYAAYGCNAARTCNTTYCARTCNMGN YTNGTNATGMGNACNCARGGNAGYYTNMGNGTNGTNYTNAAYACNAARATHTGGCCNGGN ATGACNGTNGARMGNGCNTCNTCNAARTCNGTNMGNYTNACNGCNACNGAYACNGAYAAR AGYATHAARGTNTTYYTNATHACNACNAAYAARAAYGAYTCNGARAAYYTNYTNMGNGCN ATHGAYTGGMGNATHCARCARYTNAARATHCAYGAYGAYCARCARCARYTNTCNGGNGAR GTNMGNACNMGNGAYAARMGNAARGCN---GARACNGARGCNGARGTNCCNAGYAARAGY AARAARTGYTCN------GCNGARGCNACNGCNTTYACNGTNAARAARGARGARTCNGAY AGYAGYGTNCAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TTYTTYATGYTNGARATHCAYYTNAARGARGGNMGNGAYYTNGTNGTNMGNGAYAGY TGYGGNACNAGYGAYCCNTAYGTNAARTTYAARGTNGGNGGNAARCARGTNTAYAARAGY MGNATHGTNTAYAARAAYYTNAAYCCNAARTGGGAYGARMGNTTYACNATHCCNGTNGAY GAYATHTAYMGNCCNATHAAYGTNAARGTNTAYGAYTAYGAYMGNGCNYTNCAYGAYGAY CCNATGGGNGGNGCNGAYATHGARGTNACNCARYTNGARGTNAAYMGNCCNTGYGARYTN AARYTNCARYTNAGYGARMGNGGNAARTCNGARTAYATGGGNTAYYTNYTNGTNGAYTGY ACNYTNGTNCCNAARACNCARGARGAYAARGAYCARTTYTTYMGNMGNTCNGTNMGNACN TCNGAYTCNAGYAARAARYTNAARATGCARTCNTGGAGYGGNGTNGTNACNATHGTNYTN GTNGARGGNTGGGAYYTNGTNCCNATGGAYGAYAAYGGNYTNAGYGAYCCNTAYGTNAAR TTYAARYTNGGNAAYGARAARCARMGNAGYAARCAYAARAGYAARACNYTNAAYCCNMGN TGGYTNGARCARATHGAYYTNMGNATHTAYGAYGARCARAGYACNCARYTNGARYTNACN GTNTAYGAYCAYGAYGTNGARGGNTAYGTNGTNAAYGTNGARAAYCARCAYCARCCNATG GCNAGYYTNGARGAYGTNATGGCNTAYTTYGTNGARACNTCNGGNACNGCNAGYACNTTY CCNATHTCNACNAAYGAYYTNAGYCARYTNGGNYTNGGNTTYGCNGTNGTNTTYYTNGTN AARTCNTCNACNGGNGGNMGNTTYGCNYTNAARAARATGTAYGTNAAYAAYGAYMGNGAY YTNGCNGTNTGYCARAARGARATHAARATHGCNAARGAYYTNAGYGGNCAYAARAAYATH ATHMGNTTYATHGARTCNAGYATH------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGCNTCNTCN ---GTNTCNMGNTTYYTNTCNAARCCNYTNAAYAGYMGNGTNTTY---AGYGTNGCNGCN GCNGCNGCNMGNCCNGARACNTCNCCNAGYAGYGTNCCNACNCCNAARATHAGYAARATG AGYAAYGGNATHGTNGTNGCNTCNYTNGARAAYAARTCNCCNATHGCNTGYATHGGNGTN ATGGTNAARGCNGGNCCNMGNTAYGARACNACNGARAAYYTNGGNGTNACNCAYGCNATH MGNYTNGCNTCNMGNYTNAGYAAYCARAAYTCNACNGCNTTYAAYYTNGCNMGNACNTTY CARCARTAYGGNGCNGARYTNAGYTGYATGGCNACNMGNGARCAYATGATHTAYACNGTN CAYTGYYTNMGNAAYTAYGCNAGYGAYYTNYTNCCNYTNGTNTGGGAYTGYGCNATGAAR CCNAGYTTYAGYTCNTGGGAYYTNGARGAYYTNCARAARAAYAARGAYACNTTYGARYTN GAYYTNGCNATHTAYGARAAYTCNCCNGARYTNMGNGTNTTYGARYTNYTNCAYGARGCN GCNTTYAARGAYACNYTNGGNCAYTCNYTNTAYGCNCCNMGNCAYATGYTNGGNTCNTAY AARACNGARCARYTNGCNAGYTAYGTNCARACNAAYTTYTGYGARGGNMGNGTNGGNYTN TAYGGNGTNGGNGTNGAYCAYGARATGATGAGYGARATGGGNGARYTNTTYGGNGTNTAY AARAGYACNGGNGTNCCNGARGCNAARGCNGTNTAYCAY---AGYGGNGARATHMGNGCN GARTCNGGNGGNCCNYTNGCNTAYGTNGCNGTNGCNTGYGGNGGN---AGYYTNACNGAY CARGAYYTNTGGCCNTCNYTNGTNYTNCARAAYATHYTNGGNAARGGNCCNMGNATGAAR TAYAGYAGYGGNAARGCNTTYTCNMGNYTNAGYAARGCNGTNGCNTCNGTNGCNAARCAR CCNACNTGYGTNGCNGCNATHAAYGCNAAYTAYTCNGAYGCNGGNYTNTTYGGNTTYTAY GTNGTNGGNATGGCNGAYGAYATGGARGAYGTNGTNAARACNTCNTGYAAYCARTTYMGN GARYTNGCNAGYACNGGNGTNACNGAYAARGARGTNGCNATHGCNAARYTNCARYTNAAR GCNCARGTNGCNATGGARGCNGARACNGTNGAYGARYTNTTYYTNGGNYTNGCNGAYCAR GCNTTYGGNGCNAGYAARYTNYTNTCNGCNAAYGAYATHATGAARGTNATHGAYAAYGTN AAYACNGTNGAYGTNTCNAAYGTNGCNAARAARATGATGGCNTCNMGNCCNTCNATGGCN GCNACNGGNAAYYTNAARAARGTNCCNTAYYTNGAYCARYTNATGGGNGGNAARAGYAGY AARCARAARAAYAARAARAAYAARGGNGARGGNGARGARGARGARACNGGNGARCARGTN AAYCARACNACNGARCARAAR------------------------------------GCN AAYGGNTCNGCNGARGGNGCNGCNGCNGGNGGNGARGAY------AAYGCNGCNGAYGAR AARGCNGARGARGCNAARGARGGNGARCCNACNGGNGCNAARGARGARGCN--------- ---------------------------------------ACNCCNGCNACNAGYGARGAR GCNAARCCNGARGCNGAYGCNCCNGARCARACNGCNGGNAARGAYGCNTGYACNACNGAR GAYGARCCNCCNGCNTCNTCNGAYCCNGTN---GARTCNCCNGCNCARGARACNCCNCCN GCNGCNCCNTCNGGNGAYGARGCNGCNGGNGARCARGARAARGCN---CCNGARGAYGCN CCN------------------------------------------------CCNCCNGCN CCNGARCCNGCNGARGARCCNGCN---------------------CCNGCNCARGCNGAR GARGTNGARGCNGARACNAARGARGAYTCNGTNCCNCCNCCNCCNGCNGARGARGARGCN GARACNGARGAYACNGCNGTNCARCARGARGARACN------------------------ ------------------------------------------------------------ ------AGYCCNGARCARGCNGARGGNGARACNACNGCNGCNGARGCNTCNGARACNGCN GARACNGGNGCNGCNGCNGGNGAYGGNGGNTCNGCNGARCARTCNGGNGAYACNCCN--- ------------AGYGTNGTNTGYAARGTNAGYACNGARTTYAARTGGGARGAYGGNGGN GARAAYGTNYTNGTNAGYGGNTCNTTYGAYAAYTGGCARGARAARATHTCNYTNGCNAAR ACNGGNGARGTNTTYACNGGNACNATHGAYYTNCCNGCNGGNGARTAYYTNTAYAARTTY ATHGTNGAYGARCARTGGACNATHAAYAARAAYYTNCCNGTNMGNATGGAYGAYAGYGGN CARGARAAYAAYGTNGTNYTNGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNAARTTY ACNATHGAYGTNAGYATHACNGAYYTNTCNATHACNCARGAYGAYMGNCARATGAAYTCN GTNYTNYTNATHACNACNGTNACNGGNAAYCARTGGAARYTNYTNYTNGARACNMGNACN GCNYTNTTYCARTTYTCNCCNGAYTCNGAYGTNAGYGARYTNGGNTAYGAYAAYATHGAY GGNMGNAGYATHCCNCCNMGNTCNATHYTNGAYTTYACNGARGARAAYACNGGNGTNTTY TGYCCNGTNCARTTYAGYCARTTYCARCCNCCNACNYTNYTNMGNCCNCAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TAYGAYCCNCCNGCNCCNTGYTCN GAYGAYATHGAYGGNAAYGAYTTYATGGAYTTYATHTAYTGYGTNGTNGTNCCNACNGTN GTNGTNGCNYTNYTNYTNATGYTNYTNGCNTGYATHATGTGYTGYTCN---AAYTCNTGY CARTGYMGNAARTAYTCNACNYTNTCNGGNGAYGCNAGYGARATHCARATGGARAAYTAY CAYGCNATHMGNMGNGCNTCNGCNAGYYTNMGNCAYATGTCNCAYAAYMGNGARACNCCN YTNATGGGNTCNMGNGCNGAY---TCNATGACNYTNGAYMGNCCNMGNCAYMGNMGNTCN MGNATHMGNGAYTCNTGYCARTCNGCNCCNGGNACNYTNCARMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN GGNTCNAARYTNGARAAYTAYATHAARCARTGGAAYGGNYTNGTNAARATHTTYMGNCAY GAYAARMGNCAYGGNYTNATHGCNGCNMGNTCNGCNGGNGCNAARCAYTCNACNGGNGAY GTNATHGTNTTYYTNGAYGCNCAYTGYGARTGYAAYMGNAAYTGGYTNCCNCCNYTNYTN ACNMGNATHAARCAYGAYMGNACNATHYTNGCNGTNCCNATHGTNGAYGGNATHAAYTAY AAYACNATGGCNTAYTAYTCNGTNTAYGAYCAYCAYCAYCAYMGNGGNATHTTYGARTGG GGNTTYYTNTAYAARGARTCNYTNGTNCCNGAYMGNGARYTNMGNAARMGNAARTAYGCN AGYGARCCNTAYAARTCNCCNACNCAYGCNGGNGGNYTNYTNGCNATGGAYMGNAARTAY TTYTTYGARATGGGNGCNTAYGAYCCNGGNYTNAARATHTGGGGNGGNGARAAYTAYGAR YTNGCNTTYAARGTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TAYGARGCNGARAAYTTYGCNTCNAARGTNAAYAGY GARAAYYTNAAYYTNAARMGNCARAGYCARATGYTNYTNGARAAR---GGNAAYGTNTCN GTNGTNGAYATHGAYTTYGARGAYGAYAARCARGARGARGAYACNTAYAARAGYTAYYTN GAYAGYYTNAAYGCNAARATHAARGAYYTNGARGARGCNAARTCNGCNYTNAGYGTNTAY GTNGARGARATHMGNGAYAGYTAYAAYGCNGARAARGARGARAAYGGNAARYTNYTNGTN MGNATHGARAGYATGAARATGGARATHAARCARYTNAARGCNTCNATHGAYCARTAYCAR ACNAARYTNAAYCAYATHACNTCNGCNTCNGARACNGCNGTNATGGARTAYACNAGYATG MGNAARGAYTAYGARAARGARYTNYTNTGYMGNACNCARGCNGARAARTTYGCNTCNAAR YTNTAYGCNGARMGNCARGCNGCNMGNCAYCARAGYGCNYTNYTNYTNGARGAYATHGTN GGNGAYCARAARYTNATGAARGCNATGATGGARYTNGARACNYTNAARAARGAYYTNGAR GARCARAARGCNGCNCAYAAYTCNCARGCNGCNGCNYTNAARGARGARYTNGCNGCNGCN AARAGYAGYAAYACNGTNYTNGARYTNGARAAYGAYAARGTNGARYTNATGAARGARMGN GAYTCNYTNCARAARTGYYTNGARGAYTCNGARAARATGATGAARGARTGGGARAAYAAR CAYAARCARYTNGCNAARCARTAYGARGAYYTNGARAARAARTAYGAYAARGCNGTNATG GTNCCNYTNCCNCCNCCNCCNCCNCCNYTNCCNCCN---CCNGTNGCNAARCAYGGNGGN TTYYTNTCNMGNATHAARGGNAARAARAARATHAARGAR---------GARAARYTNAAY AARAGYGGNGCNCARGTNAAYGARGGNTTYAAYAARGCNYTNGCNGARATGATGGAYMGN ATHAARTCNGGNACN---GCNYTNMGNCCNGTNYTNAARAARCCNACN---------CAR TCNGTNACNGARGAYMGNTCNTCNGTNGCNATGGAYCARYTNCARAGYATHYTNAARAGY ATGAARAARAGYMGNAGYGARGARAAYYTNGTNTTYCCNGAYGARGAYGARACN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TGYGGNGAYTAYYTNGGNGAYMGNGCNTTYYTNGCNYTNCARGCNTTYATHAAYGCNYTN TCNAAYYTNMGNACNGCNGCNGGNGTNGAYTTYGGNTTYYTNGCNYTNGAYGAYTGYTAY AGYCCNACNMGNGCNGCNAARATGGTNAGYAAYATHYTNAGYGGNGARATGTCNATHGTN GAYGCNGCNACNGGNACNACNYTNGAYGTNAARMGNGTNGCNGTNGCNGTNGGNGCNCAR TCNAGYTCNGTNACNCARGCNGTNYTNCCNATHYTNAARAARYTNGGNATHCCNYTNATH TCNTAYAGYTCNACNAGYCCNGARTTYGAYAGYMGNATHMGNTAYCCNTAYTTYYTNMGN ACNGTNAGYAGYGAYACNGTNCARGCNGAYGTNATHGTNCARYTNYTNAARCARYTNGAY GTNACNTAYGTNGGNTCNATHATHATHAAYAAYAAYTAYGGNCARGARYTNGAYCARCAR TTYMGNGCNAARGCNGARGCNGARGGNATHTGYGTNAARCCNGCNYTNAARATHAGYGAR ACNGTNACNCARGAYGAYATHAARCCNGTNYTNCARGARTAYMGNGAYGAYAGYGTNCAY GTNGTNGTNGCNTTYGCNATGGAYAARGTNGCNATHCARATHYTNMGNGTNCARGARGAY GAYACNTTYGTNTTYATHGCNAGYGARGCNTGGGGNCCNAAYCARCARATHATHGCNGAY AAYMGNGGNGARMGNGCNMGNGGNTCNGTNGTNYTNGCNGCNGAYAGYGARMGNGTNCAR GAYGAYYTNAARGAYTAYATGMGNAAYYTNACNCCNTGGGTNAAYGAYTCNTGYCCNTGG YTNMGNGARTTYTGGCARAGYCAYTTYAARMGNTCNGAYGGNGAYYTNMGNGAYGAYMGN GAYMGNGAYMGNGAYMGNGAYMGNGAYMGNGAYMGNCCNGTNMGNMGNATHGGNAGYGGN MGNATHCARYTNGAYMGNGARGGNAGYMGNGARTTYCCNAGYAAYMGNGAYMGNTTYGAY GAYGAYMGNGARMGNGAYMGNGAYMGNGARMGNGGNTGGGAYMGNGAYMGN---GAYMGN GAYMGNGAYYTNGAYTGGGAYMGNGAYMGNMGNATGGAYMGNGAY------GAYMGNGAY MGNGAYTGGGAYTGGGAYMGNMGNACNGARGCNYTNMGNMGNTCNTCNGAYTCNCARTAY TCNGAYMGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ACNATHACNAAYGARTCNTCNTCNCAR ATGTAYGARACNGCNGARGCNGAYTGYCARGTNATHAGYTCNCCNGARTTYGGNTGGCCN CARACNGTNTTYYTNCARACNAAYAAYTGYCARTAYTCNCCNTAYAAYYTNCAYTGYGTN CARGTNYTNCCNGGNATHACNYTNGTNGTNYTNTCNCARGCNCCNMGNCAYACNYTNGCN GAYTCNYTNTAYCARGCNYTNACNATHATHCARGAYYTNATHTAYGGNMGNMGNGARAAR YTNAGYMGNTCNMGNGGNYTNCAYGTNTAYGAYGTNATHTTYTCNYTNYTNGGNAARGTN CAYACNGCNYTNAARAARACNMGNGGNMGNGTNMGNAAYYTNAGYGCNGAYGTNTTYTCN MGNTGGGARAGYGARGARYTNAARTTYAARYTNYTNACNTAYYTNGARMGNGAYGCNMGN ACNCCNATHGCNCCNGAYYTNGARTCNYTNYTNAGYGARYTNTAYAARMGNYTNAARGAR YTNTTYGCNYTNYTNTTYYTNAGYCCNATGCCNGARAAYTCNGGNYTNATGCARGTNGTN TCNCARYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNTGYGCNGTNGAYGGNYTNMGNAGYAARATHMGNYTNTTYCARATHAAYACNGAR GARGCNATHTAYATHTGYGARAAYTCNAAYTGYACNTTYATGYTNGARACNCCNAGYGAR ACNYTNATHGTNAGYMGNAAYATHTCNGARATHTGYYTNCCNTCNCCNTCNMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYATHTCNMGNAARAARMGNAGYMGNAGY MGNGARMGNAGYMGNGAYMGN---------------------------AGYAARGAYAAR GAYMGN---------------------------------------AARMGNTCNAARAGY MGNGAYMGNGAYMGNAARMGN---MGNGAYMGNGAY---GARMGNMGNMGNAGYMGNAGY CAYGAYMGNGAY------MGNMGNMGNMGNAGYAARTCNCCNMGNMGNAGYMGNTCNMGN AGYCCNMGNMGNAAYAARMGNGARCCNGARYTNACNCCNGARGARMGNGAYGCNMGNACN GTNTTYTGYATGCARYTNGCNGCNMGNATHMGNCCNMGNGAYYTNGARGARTTYTTYTCN TCNGTNGGNAARGTNMGNGAYGTNMGNATGATHGCNGAYAAYAARACNMGNMGNTCNAAR GGNATHGCNTAYGTNGARTTYGCNGAYTCNGARTCNGTNCCNYTNGCNATHGGNYTNTCN GGNCARAARYTNYTNGGNGTNCCNATHATGGTNCARTAYTCNCARGCNGARAARAAYMGN CARAAYGCNGCNGCN---GCNACNACNTCNTCNAAR---CCNAGYGAYGGNCCNATGMGN YTNTAYGTNGGNTCNYTNCAYTTYAAYATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TAYGARGARGAYTTY ATHGGNGARMGNCCNAAYATGGCNCCNTCNATGGCNAAYYTNGARATHTCNGARGARYTN MGNGCNTCNTCNTCNTCNYTNGCNAARMGNAGYATGGTNYTNGAYCARGARACNTTYGAR GAYCARTTYYTNMGNTGYGGNATHTGYAARGARATGTTYGGNCCNGGNMGNYTNCCNAAR YTNYTNCCNTGYCAYCAYTCNTTYTGYGTNYTNTGYATGATGMGNATGTTYATHCARGAR ACNGARCAYAARCARACNYTNGCNGTNAGYCAYMGNTCNGTN------------AAYGCN GTNAGYATHTTYTGYCCNACNTGYMGNCAYAAYTTYATHGCNACNGAYGAYAGYATHAAR AARYTNCCNACNGAYCAYMGNATHGTNCARYTNYTNGAYTTYGTNAAYCAYACNGAYMGN TAYACNATHACNTTYTGYTCNAARCAYAARYTNCARCCNYTNAAYTTYTTYTGYGARCCN TGYGTNAARCCNGTNTGYMGNGAYTGYACNGTNYTNGAYCAYMGNGARTCNGARAARCAY YTNGTNATGGAYYTNGAYCARGCNYTNTCNAARTAYACNCCNATHYTNGAYMGNGAYATH GCNGARATGGAYAGYGARCAYGTNYTNYTNGARGARAARMGNATHGCNYTNGAYACNGTN AGYAAYGCNYTNGARGCNTCNAARACNGARGTNYTNAGYCARYTNAARTCNTGYATGCAR MGNYTNCAYCARATHYTNGAYGAYMGNGARAARGARYTNGARGCNAARGTNYTNGAYGAR GTNGGNAARGARAARGCNAARYTNGCNGARAARGTNGARYTNATHGCNTCNMGNMGNCAR AARYTNCARATHCAYGCNAARCARYTNMGNCARGCNAARGARGAYAAYAAYGTNGARGAR ATGTTYATHGTNCAYGARGARGTNMGNAGYTTYMGNAGYCARGGNAGYATGMGNATHMGN GARGTNGAYGAYGGNGTNATGACNACNTTYTTYYTNAAYGCNMGNGAYGARAAYACNYTN GCNTCNMGNATHAAYAAYTTYGGNAAYYTNAGYACNAARGTNGARGCNACNGGNGCNMGN GTNAARCCNAGYATGAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNMGN GARGARATHYTNAAYMGNAARAAY---AARAARGTNTCNGCNGTNATHGAYTTYGAYTAY YTNGAYTCNYTNATHTCNACNAAYGCNAGYCARTAYGCNTCNACNATGTCNYTNAAYCAR TCNACNTCNAARTCNTCNATHACNTCNACNATGGGN---CCN---MGNAARTCNMGNGTN TAYGCNMGNGTNAAYAARTCNGTNCAYAAR---ACNGCNTCNTCNCCNTCNCCNMGNAAR GCN---TCNCCNTCNTCNTCNCARGAYTCNAAYGTNATHGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TAYATGGARTCNCARGGNGCNCAYAARGCNGGN YTNGCNAARGTNATHCCNCCNAARGARTGGGTNCCNMGNAARAGYGGNTAYGAYGAYGTN GAYYTNATGATHCCNGCNCCNATHGARCARGTNGTNTCNGGNCARCARGGNYTNTAYACN CARTAYAAYATHCARMGNMGNGCNATGCAYGTNAARGARTTYGARGARATGGCNAARTCN AARAARTAYGCNCCNCCNCCNCAYTTYGAYTAYGAYGAYYTNGARMGNAARTAYTGGAAR AAYGTNACNTTYGGNCARGCNATHTAYGGNGCNGAYATHTCNGGNTCNYTNACNGAYGAY GAYCARGAYTTYTGGAAYATHAAYMGNYTNGGNACNATHYTNGAYTAYGTNAARACNGAY TAYGGNATHAARATHGARGGNGTNGTNACNGCNTAYYTNTAYTTYGGNATGTGGAARACN ACNTTYGCNTGGCAYACNGARGAYATGGAYYTNTAYTCNATHAAYTAYYTNCAYTTYGGN GCNCCNAARTCNTGGTAYTGYGTNCCNCCNGARCAYGGNCARMGNYTNGARMGNYTNGCN CARGGNTTYTTYCCNGGNAGYTTYAGYGAYTGYCCNGCNTTYYTNMGNCAYAARATGAGY YTNATGTCNCCNTTYATHYTNAARAARTAYTCNATHCCNGTNAAYAARATHACNCARGAR GCNGGNGARTTYATGATHACNTTYCCNTAYGGNTAYCAYGCNGGNTAYAAYCAYGGNTTY AAYTGYGCNGARTCNACNAAYTTYGCNACNATGMGNTGGATHGARTAYGGNAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GAYCCNACNTAYGCNATHATHYTN ACNYTNTTYTCNGGNGTNGTNCARYTNGTNATGGGNATHYTNAARYTNGGNATHYTNGTN AGYTAYATHTCNTTYCCNGTNATHAAYGCNTTYACNTCNGCNGCNGCNATHACNATHGCN GTNGGNCARATHAARAAYATHYTNGGNYTNAARGAYATHAGYMGNGARTTYATHCAYACN GTNATHGARACNTGYGARAARGTNCCNGARACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CCNMGNGAYMGNAAY GTNCCNYTNCCNYTNCCNCCNGGNTCNATGGGNTGYCCNGTNYTNGGNGARTCNYTNAGY TTYGCNATGAARGGNTCNGAYTTYYTNGTNGAYAARTAYAAYCARTAYGGNAAYATHTAY MGNACNCAYYTNYTNGGNTCNCCNACNGTNMGNATHTCNGGNGCNCARAARATHMGNCCN GCNYTNACNGGNGAYYTNAAYGTNATHTCNTCNGTNGTNCCNAARGGNTTYYTNAARGTN YTNGGNCCNGAYAGYGTNTTYGTNTCNGTNGGNGARCARCAYAARMGNYTNAARMGNCAY ATHYTNAAYGCNTTYACNCCNYTNMGNYTNTCNTCNTAYYTNCCNCARATHCARTCNYTN ATHMGNTCNGCNYTNYTNGARTGGTGYGARMGNGGN------------CCNATGYTNGCN TTYCCNGCNTGYGARGAYYTNGTNGCNTCNATHACNYTNGARYTNGTNACNGGNTGYACN TCNACNCAYAGYAARTAYGGNCARYTNYTNCARGCNYTNMGNGAYGCNAAYTAYAGYATG TTYAGYATHCCNATHAAYGTNCCNGGNGGNGCNTAYMGNAARGGNATHGCNGCNMGNAAR GTNATHTGYGAYTTYATGAARGAYGARATHGCNAARCAYGGN---GAYAAYGAYTAYGTN MGNATHATHGAYATHATHYTNCARGGNCAY------------------ATGAGYCCNYTN GARACNATGGAYAAYYTNATHAGYYTNYTNATGGCNGGNTCNATHACNTCNAGYAGYGCN TGYTGYTCNGTNATHCAYATGYTNGGNAARCAYCCNGGNTCNNNNGCNMGNGTNMGNAAR GARYTNGAYNNNCARGGNYTNACNGAYGARGARGGNGGNGGNGAYYTNACNTAYGAYYTN YTNGARAAYYTNCARTAYGTNAAYAAYGTNGARAARGARGTNYTNMGNYTNYTNCCNCCN GTNGGNGCNGCNATGMGNAARGCNGGNAARACNYTNGARYTNGAYGGNTAYCARATHCCN GCNGGNTGGMGNGTNATGTGYAGYATHMGNGAYACNCAYCAR---CARTCNCCNYTNTTY ACNCAYMGNGAYCARTTYATHCCNGARMGNTGGGARCARATGGGNGTNGARAARMGNMGN MGNGAYGAYYTNMGNTTYAAYTAYYTNCCNTTYGGNGARGGNGCNMGNAARTGYYTNGGN MGNCCNYTNGCNCARYTNATHATHCAYGCNTTYACNGTNGARYTNGCNMGNYTNACNGAY TGGACNYTNGCNAGYCCNGAYGCNACNTTYGTNTAYYTNCCNACNACNAARACNGTNGAY GAYYTNCCNGCNACNTTYGTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GTNAARYTNGGNCARGARAARGAYTTYATHGAYTGYYTNGTNGAYTGGTGY GAYGTNGAYGARCAYGCNGGNGTNAARGGNGARGCNACNMGNYTNATGTCNTCNYTNGTN AARAAYAGYCARTCNAGYGCNGTNGTNAGYAAYYTNATHMGNGCNGARGGNYTNCARTAY YTNGTNACNATGGTNACNAGYGARCAYATGGTNATGCARAAYGARGCNYTNATHGCNYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GAYATHACNTTY ACNGGNTAYCARMGNTTYAAYTCNAAYAGYGTNTAYAARCARTTYYTNMGNYTNAARTAY AARGTNTGGATGTCNTAYCARGAYGARGARATHTGYYTNGARACNYTNTCNYTNCCNTTY GTNTTYTCNACNGGNTCNAAYCARATHTGYGARCAYATHGGNACNYTNATGTGGTAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARCAYGARGAYCAYATHCARCAR YTNCARGTNGARAARAGYGTNATHGCNGAYGTNCAYCCNGGNGAYGCNGTNTTYTCNCCN GCNMGNTTYGGNCARYTNTAYMGNGARGCNATHYTNCCNYTNGAYTAYGGNTTY---AGY TCNAGYGTNTCNGCNATHGAYMGNATHATHTCNTCNGTNCARCCNGARACNYTNYTNGAY ACNYTNATGTCNAARGTNATHCCNAARTGYTTYCAYMGNGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGAGYAAY MGNAAYAAYAARGTNMGNGTNTGGGGNMGNYTNMGNCCNACNACNCARTTYGCNCAYGAR AAYATHGARYTNYTNCCNGAYAAYAARAGYATHAAYGTNCAYATHMGNMGNGAYCCNAAR AARGGNGTNGTNAAYAAYCARATHYTNGAYTGGTCNTTYAARYTNGAYGGNATHTTYAAY AAYGCNGAYCARGARGTNGTNTAYAAYACNGTNGTNTCNGAYATHGTNACNTCNTCNYTN GAYGGNTAYAAYGGNACNYTNATGTGYTAYGGNCARACNGGNGCNGGNAARACNTTYACN ATGACNGGNGCNACNGARGGNTAYCARCARMGNGGNYTNATHCCNMGNGCNATHTCNCAR YTNTTYMGNCARATHGARGAYMGNGTNGARCAYAGYATHACNGTNMGNATHTCNTAYATG GARATHTAYAAYGARAGYATGTTYGAYYTNYTNGGNGCNYTNCCNGAR---TCNTGGAAY CARCARAAYAAR------------------GARCCNATGAAYATHACNGARAAYCARGAY GGNGTNTTYGTNAARGGNYTNTCNTGYCAYYTNGCNCAYAAYGARGARGARGCNYTNAAY YTNYTNTTYGARGGNGARACNAAYMGNGCNATHGCNGCNCAYAGYYTNAAYAARCAYTCN TCNMGNTCNCAYTGYATHYTNACNGTNTAYYTNGARTCNMGNTCNMGNGTNCARTCNAAY GCNAARTAYACNGTNTCNAARYTNAAYTTYGTNGAYYTNGCNGGNTCNGARMGNYTNGGN AARTCNATGTCNGARGGNAARACNCARCARGARGCNATGTAYATHAAYAARTCNYTNTCN TTYYTNGARCARGTNGTNGTNGCNYTNGCNGAYMGNCAYMGNGARCAYGTNCCNTTYMGN CARGCNAARYTNACNCAYTAYYTNAARGAYTCNATHGGNGGNAAYTGYAGYACNYTNYTN ATHGCNAAYATGTGGGGNGARAARGCNCARYTNGARGARACNGTNTCNACNYTNMGNTTY GCNACNMGNATGATGTGYGTNGCNAGYACNCCNGCNATHAAYGARGTNTAYGAYCCNGCN YTNYTNGTNAARAARYTNCARMGNGARATHATGCAYYTNAARTCNGARYTNGCNATGCAY GAYACNYTNACNAAYMGNAGYYTNATHTCNTAYGAYGCNYTNTCNGARCARCARAARTAY GARATHMGNATGCARTGYMGNMGNTTYYTNGARGGNAGYYTNGAYGARATHGAYATHGTN AAYYTNMGNCARATHCARGGNACNTTYGAYTCNTTYMGNGARATHTAYAARGAYYTNGAR AARGAYGTNGARGARMGNYTNMGNCARAARTTYATGYTNATHGAYAARACNGAYCCNAGY TCNATHGCNGCNGCNCARCAR---------------GTNTGGTTYGARGARGARGARGAY ATHCARGCNGGNGTNCCNATHACNGAYGAYGGNTCNYTNGTNGGNGARYTNGAYGGNGCN GGNTTYAGYGTNGGNGTNGCNAGYAARGCNAGYAARGCNGARCCNTCNGCNGTNGTNCAR YTNAARAARAARGARAARGARMGNGARAARAARAARGGNGGNMGNGGNGCNAGYAGYCCN GTNGCNGGNAARACNGCNTCNAGYCCNTCNCAYAGYGCNAARGGNGARMGNAARGTNGAY TCNCCNCCNACNCCNGGNGTNGARAARGCN---------GARAARGAYATGGARGGNTCN ACNTCNCCNGTNAGYTCNGCNGGNAAYYTNTCNMGNACNGARAARGCNGCNMGNCCNAGY ---------------------------------------------------ACNCCNCCN AGYMGNACNTCNGCNTTYGARGARTTYAARCARGAYMGNGGNGTNGARATHAAYMGNYTN YTNGTNCARAAYAARGARACNYTNGCNAGYAARAARAARGARTAYTCNAARYTNGCNGCN YTNATHAAYGGNACNAARAARGAYATHGAYGAYACNMGNCAYYTNYTNCARGAYYTNAAR GARCARMGNGARGCNGAYGGNCCNATHTTYAAYGAYGAYGGNGAYATHGTNATHAGYGAR GARGARTTYAAYCARATHCARMGNYTNAARAAYYTNAARGARATGTAYMGNGGNAAYTAY AAYGAYYTNCARMGNYTNAARTCNGARGTNGCNTAYTGYCARAARATGGTNGAYCARAGY MGNYTNAARYTNATHCARGARTTYGAYAAYTGGTAYGCNGARAGYTTYYTNACNTCNAGY GARGAYCCNAGYTCNAGYYTNGCNACNGGNTAYGGNATHMGNCCNGGNGTNATGGTNCCN YTNAAYAAYYTNTCNACNGARGAYGARCARGARAARTTYGARMGNYTNCARYTNGARYTN ATGATGAAYAAYCCNGAYTCNGCNGCNTTYTAYAAYGCNCARATGMGNACNAGYMGNMGN AARATHTAYGGNAGYGCNYTNAGYCARCCNCARCCNAGYTAYMGNMGNACNCCNGGNACN CCNACNATHACNATHMGNAAYAARCCNCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ACNYTNTAYTGGACNGTNTTYGGN TTYCARAGYAAYTTYGAYAARGCNMGNAGYGGNACNAAYACNMGNYTNTCNAGYCCNGAY TTYTAYYTNTCNYTNGGNGGNTAYAARGCNCARYTNCAYGCNTAYYTNTAYGGNAARGGN GTNGGNAARGGNACNCAYTCNACNGTNTCNYTNTCNYTNATHCCNGGNAGYCAYGAYGAY AARYTNCARTGGCCNGTNYTNCCNTGYMGNACNGTNACNYTNYTNGAYCARACNTCNGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGGGNACNAAYCCNAARAARCARTCNAAR TCNTTYAARGTNYTNCARTGGATGACNGARACNGARCARGAYGAYGCNAGYCARCARGAR GAYAARACN---------------ACNAGYMGNGGNMGNMGNAAYMGNGAYCCNGARYTN MGNCAYAAYGCNGARGAYGAYGARATGMGNTTYACNGGNYTNCAYCCNAARACNTCNATH CCNTCNAARTCNTTYAARACNYTNCARCARGTNCCNGAYGAYGGNAGYAGY------AAY TAYAAYGGNMGNGCNGCNGTNGAYGGNGGNGAYGAYGARGARMGNGTNGGNAAYTAYGAY GARACNTCNATHMGNTAYAARGGNAARAGYATHCCNTCNCCNTCNTTYMGNGTNYTNCAR ACNTGGGCNGARTAYGAYCARGCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGGNAAYGGNATG AAYAARGTNATGACNGGNYTNTTYGTNGGNAAYTTYMGNGAYGCNAARGAYCARAARCAR YTNACNGAYAAYAGYATHACNCAYATHGTNTCNATHCAYGAYAAYGCNAARAARYTNYTN GARGAYAARGARTAYYTNTGYATHYTNGCNAGYGAYAAYCCNGAYGARGAYYTNACNMGN TAYTTYGCNCARGTNAAYMGNTTYATHCAYAARGCNMGNYTNGARGGNGGNAGYGTNYTN GTNCAYTGYYTNGCNGGNGTNTCNMGNAGYGTNACNGTNACNGCNGCNTAYATHATGTCN GTNACNAAYYTNGGNTGGMGNGARTCNYTNAAYGCNATHMGNGGNGTNMGNAAYTGYGCN AAYCCNAAYTTYGGNTTYCARAARCARYTNCARAAYTAYGAYCAYGARCAYGTNGARGAR GARMGNMGNMGNYTNAARGCNGCNTTYCCNAAYAAYTGYYTNAGYGAYGARGAYGARTGY MGNMGNAAYATHCAYAGYTTYCARCAYTAYGTNATGACNGGNAAYYTNCCNTCNCAYTCN GAYGAYYTNTAYCCNYTNCCNCAYMGNGCNTAYAARYTNCARGCNYTNCAYATHGCNAGY TAYGARTGYATGAARATGCARYTNCARAGYYTNMGNGARCARYTNCARGCNAARACNGGN MGNGAYCCNGTNGCNYTNCCNGCNGAYTCNAAYGCNAGYGTNGAYTTYGARTCNCAYTCN GARAAYGCNAGYGARGAYCCNGTNYTNGARATHTCNYTNACNTGYTCNGGNYTNCCNTGY GAYGTNAAYAGYGTNCCNCCNAAYCCNYTNGTNGTNGTNCAYACNATHYTNCCNCCNCAR CARCARYTNTGGATGCAYCAYAAYCAYACNGARATHGTNGARAARAAYAAYAAYCCNCAR TTYYTNAARACNATHGGNTTYGGNGAYAARTTYGGNATHGAYACNAGYACNMGNGTNMGN YTNACNGTNTAYCAYGTNGTNGARMGNATGACNATGACNCARYTNGGNCARGCNATHTTY ACNYTNCARGAYYTNYTNYTNACNCCNGAYYTNAGYATHTCNYTNAARYTNCARGGNCAY GAYGGNGARATHACNGTNACNGCNTGGATHAAYGAYAAYCARATHGTNYTNTCNGAYYTN MGNCARCARCAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARGARAARTAYTGYTCNAAYTGYAARAARAAYATHGCN GCNTCNAAYTTYGTNATGCAYGARATGCAYTGYMGNMGNCAYATHGTNYTNTGYGARCAY TGYGCNGARCCNATHCCNMGNGCNGARYTNGAYCARCAYTTYCARGAYGTNCAYGCNAAR ATHCCNTGYAGYCARTGYCARCAYAARGTNGARAARTCNCAYYTNGAYGAYCAYYTNAAR TCNGARTGYCCNAARMGNYTNMGNTGYTGYGARTTYTGYAAYYTNTCNGTNCCNGCNGAY GCNTTYTCNGARCAYGARGARTAYTGYAARACNMGNACNGARAARTGYGAYYTNTGYGGN MGNTAYATHATGYTNGCNGAYMGNYTNMGNCAYGARACNAGYAGYTGYACNTAYCCNAAR GTNTCNCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR GAYGTNGAYTTYGAYGAYATHGAYGAYATHGAYMGNGCNYTNGARAARGCNYTNATGAAR AARYTNGARAARAARAARGCNGARYTNGARAARYTNGGN---TCNAARGAYGAYAGYAAY ATGGCNATGYTNGARCARGAYAARCARGTNACNGAYGGNGGNAGYGAYAAYMGNAARMGN MGNCAYGCNGAYATHGCNTGYGAYGCNTCNCARGAYGAYGAYAARYTNAARAGYGARATG MGNGAYATGGCNAGYGTNGCNYTNGCNAARYTNGARTTYYTNGAYATHTCNACNAAYAGY YTNTCNAARYTNCARATHYTNYTNATHCARATHCARACNMGNYTNGARGAYTGGGARGCN GGNGGNYTNTCNAGYGARTAYYTNCAYGCNAGYYTNMGNCARGCNGARTCNYTNYTNTAY CARTAYGARGCNAGYGCNGTNCCNGAYGGNTGGGCNTGYCAYTGGGAYMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNNNNNNNNNNNNNNNNACNGARCARATHGTNCARGAYGCNTCNGTNACNTTY YTNACNMGNGGNAARGTNGCNTCNTAYACNCARCAYMGNGGNTCNGTNCCNYTNTTYTGG TCNCARGAYATHTCNAARATGGTNCCNAARCCNCCNATHACNYTNGAYTAYMGNGAYCCN TAYCAYAAYGCNGCNGGNATHCAYTTYAAYCARYTNYTNMGNMGNTAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNGARGARYTNATHCAYATHTAYGAR ACNAARAAYCCNCCNYTNGARGARYTNMGNTCNCAYGCNGCNATHTTYGTNGARGARACN CARGAYCCNYTNGCNYTNMGNCCNCCNACNGARGARGARCARMGNATHATGACNCARGGN GTNAAYAGYACNATHGTNYTNMGNATGAAYMGNGGNGGNACNGTNGAYMGNGGNMGNGGN MGNGGNMGNGGNTAYATHGGNAAYTAYGAYGAYMGNMGNCCNCCNAGYMGNGGNGAYGAY TCNMGNGGNCCNMGNMGNATHAGYGAYTCNTTYGAYAAYGTNCCNGARTGGTCNGTNGAY GAYAAYYTNGAYGAYCCNGGNACNTTYGAYTCNTCNGGNGCNTTYGTNGCNYTNAARGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CCNGCNGAY---CCN MGNCARMGNTAYAAYTAYAAYGCNGTNAARMGNGARYTNGCNGARGARMGNAARAARGAR TAYAAYCARYTNYTNTCNGARAARGCNCARCARMGNCARCARMGNACNGARAARGARATH GAYGARCCNACNATHATHCCNTTYGAYMGNCCNGAYCARGAYAARMGNAARCARMGNYTN ATGGARGARGARMGNMGNMGNGARTAYAAYGARGTNAARGCNAARATHGAYGARAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MGNYTNGCNYTN ACNTAYGCNGTNAGYGAYGARGTNGARGCNGCNAAYGGNAARYTNAAYGTNGCNCAYTTY CAYCARGTNTGYAARAGYYTNMGNGARACNYTNGARAARGARGTNGARACNYTNYTNGAR GAYATHGARTTYYTNCARACNTGYYTNGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNCCNGCNGARGARCCNCCNAARTAYCCNTCNTCNTCNCAYTAYACNMGNGAYTGG GAYMGNYTNGCNGCNGARGTNACNGARGARGARAARAAYGARAARYTNGARGGNGAYGCN GCNYTNAAYAARTTYTTYAARCARATHTAYTCNGAYGCNTCNGAYGARGCNMGNMGNGCN ATGATHAARTCNTTYTCNGARTCNGGNGGNACNGTNYTNAGYACNAAYTGGAARGARGTN GCNGAYGGNAARGTNGAYGTN------------------------------------YTN TTYGARATGCCNAARMGNAARGCNGTNCARACNCCNAGYMGNAAYGCNCARGARAAYGTN GAYGCNGAYGAYACNCCNTCNCCNGCNAARYTNAAYAARCCNGCNGCNACNCCNAARAAR AGYACNGGNAAR---MGNGGNMGNCCNCCNYTNTCNGCNGARGARMGNGCNAARMGNGCN CARATHAARGARGAYTCNTCNGGNYTNGGNMGNGGNMGNCCNAARGGNTCNACNAAYAAR ACNAARAARACNAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------AAYAAYAARTAYGAYYTNATGGARACNTGGAARGCNYTNGARTTYGTNGTNAGY TCNCARAARYTNCAYAGYATHGGNGTNTCNAAYTTYACNGCNAGYCARATHGARMGNATH YTNCAYAARGCNMGNGTNCCNATHTCNAAYYTNCARTGYGARTGYCAYGTNTAYYTNCAR CARCARAARYTNMGNGARTTYTGYCAYTCNCARGGNATHGTNATHTCNGCNTAYGCNCCN YTNGGNGCNCCNGCNTAYCCNGAYAARGAYAGYACNTCNACN---GTNYTNYTNGARGAY GAYGTNGTNAARTAYATHGCNGARAARAAYAARMGNACNCCNGCNCARATHYTNYTNAAY TTYYTNYTNTGYAARGGNTTYGTNGTNYTNCCNAARAGYGCNAAYCCNCARMGNGTNCAR GARAAYTTYGAYATHYTN------------------------------------------ ------------------------------------------------------------ ---------------GTNGCNMGNYTNTTYACNTGGGCNGARAGYGCNGARGARCCNYTN MGNTCNTAYGCNACNGGNYTNYTNGCNGGNGCNATGGARYTNAAYGAYATHGCNTGYAAY TAYAARGARAAYAAYCARCAYYTNGTNCCNYTNATGYTNAGYMGNYTNMGNGARYTNTGY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TGYTGYGGNTCNGAYAAYCCNCARTAYCARAAR GCNYTNMGNYTNYTNGCNMGNTGGYTNCARACNACNAAY---MGNTCNCCNGAYATH--- YTNAARGCNCAYYTNAARAARYTNYTNMGNGGNATGCCNGCNYTNTTYAARGARTTYYTN GTNTTYTTYCARAGYGARCCNCCNCCNGAYGCNTAYGARGARGAYTTYGARGAYGTNACN YTNCCNGAYAARGAYGARGAYGTNGAY---ATGGAYGAYTAYGARGARATHGTNYTNCCN GAYGCNGTNGAYGCNTAYAAYACNAARGAYTGYCCNTGYMGNTGYCAY---TCNAGYGAY GCNGAYGARMGNATGMGNMGNMGNYTNAARCAYTGYYTNTCNTGYAGYTTYAARATGTAY GAYGAYAARCCNGTNTTYCAYGTNTCNMGN------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNAGYCCN CCNYTNAAYTGYGCNGAYGAYMGNACNYTNMGNCARMGNAAYMGNGTNMGNAARAARYTN CARCARMGNCARMGNATGAAYGCNGTNGAYTAYTAYCCNCCNAGYMGNCCNGTNGGN--- ---MGNMGNMGNGTNGGNATHAAYGGNGAYGCNAAY---CAYGTNAAYATHATGGGNAAY CAYGGNAAYGARAAYGGNCCNACNGAYYTNGARGARGAYAAYACNYTNATHGTNCARTGY YTNTCNAGYYTNCCNTCNCCNAARGTNACNGAYATHGARGCNMGNAGYGCNYTNATHCAR YTNTCNCCNCCNGAYTGYGAYTCNAAYYTNGARYTNGAYCCNTCNGAYTTYAARTAYGAR YTNYTNYTNTCNGAYAARAGYMGNGAYGCNAARTAYAARACNGTNTTYATGGARCAYTAY GARYTNGTNCARGARATGCCNTCNATHGARMGNATGGCNACNCARGAYMGNYTNAARCAY GCNMGNAARMGNMGNYTNCARCARYTNAARAARTTYTCNCARTAYGARAARCARYTNGAY AARGARAGYAGYAARAARAARAARAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHTAYGGNYTNGARAARTGYMGNATHTGYAARAARMGNTCNAGYAAR GARGAYGGNGGNAARGARAGYATGGTNAARTGYTCNCARTGYGGNAARATHGGNCAYATG AGYTGYYTNGAYYTNACNGARGARYTNGTNGCNGTNATHAARACNTAYCCNTGGCARTGY ATGGARTGYAARACNTGYGTNAARTGYATGGAYCCNTAYGAYGARGAYAARATGATGTTY TGYGAYMGNTGYGAYMGNGGNTTYCAYACNTTYTGYATHGGNYTNGCNGCNATHCCNACN GGNCAYTGGGARTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------MGNMGN TGYAARYTNTTYTAYAARMGNGARTCNGARTGGGTNGARMGNGGNYTNGGNAAYGTNCAY GTNAARCCNYTNGAYGGNGGNAAYACNCARYTNYTNGTNMGNGCNGAYACNAAYYTNGGN AAYATHYTNYTNAAYGTNATGATHTCNTCNACNACNCCNYTNAARMGNGARGGNAARAAY AAYGTNTTYYTNGTNTGYATHCCNAAYCCNCCNATHAAYAAR---------------GAY GAYACNTCNGCNCCNGTNCCNATGYTNATHMGNGTNAARACNGCNGARGAYGCNGAYGAR YTNTTYAAYGTNYTNGARGGNMGNAAR---------AARTCNTCNGAYTGGTAYCARCAY TCNGGNGAYCCNGCNTCNMGNCCNGARGCNMGNYTNMGNTCNACNGARGCNMGNGAYATH GCNACNAARAAYAARGGNTGYATGGAYGARGTNATGGGNGGNTAYGCNAAYCCNGCNCCN TCNMGNCARACNCAYCCNMGNGGNGTNACNCCNGARGTNTGGGAYAARGCNGARGCNCAR MGNGARGGNTCNGTNAARACNYTNATGAAYAGYTAYGGNMGNYTNAGYGTNGARGAYMGN CCNGCNCCNAARGTNAARGGNTGGGARGCNGARATGAAYAARGARMGNGARCARGGNACN ACNAARGTNYTNYTNGAYCAYTAYAAYCCNGCNCCNATHCCNACNGGNGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNCARACNGARTGGCCNYTNCAYCCNGCNGGNCAR ATHYTNCAYATHATGGARGTNGARGAYAGYGGNACNTGYGGNGARGARGCNAARTAYTGY GCNACNTGGTCNCAYCCNMGNCAYTTYGAYMGNATHATHATHAGYCAYAARATGGTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GTN YTNACNATHATHGARCCNAAYATHTCNCARATGTCNGAYAARYTNGAYCARTGGYTNGGN GAYYTNAARGGNAAYATHYTNGCNGARTAYACNCAYGGNGCNATGYTNAGYATHCARGCN CARMGNGARGCNTGYMGNAARGARATHGAYCARYTNGCNTCNGAYAARMGNCARYTNCAR MGNGARGTNAAYMGNYTNAAYGARYTNGCNCAYACNTGYCARACNACNATHAAYMGNAAR GAYGARGTNYTNAARAAYYTNTCNGAYGCNATHGCNMGNCARMGNGARMGNATHAAYYTN TCNAARAGYTTYTAYGARTGGAARAGYCARAARGCNGAYGCNAARMGNGARGCNTTYACN ACNAARYTNGCNCARCARCARTAYCARMGNATHYTNACNMGNMGNGTNYTNMGNGCNTGG TTYTCNGTNATHCARTCNMGNTGGAARACNMGNGTNGARAARCARTGYCARGCNMGNGCN CARGARGTNTGYATHCARYTNACNGGNGARTAYGARGAYAARGTNGCNGCNYTNAAYGCN AARATHGCNMGNYTNGARGARAARGTNGCNAGYATGCARACNGARMGNGARAGYTAYGAR GARCARATGAARAARGCNTTYATGMGNGGNGTNTGYGCNYTNAAYATGGARGCNATGACN GTNTTYGGNAARGARGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG GGNMGNAARAARATHCARATHTCNMGNATHGGNGAYGARMGNAAYMGNCARGTNACNTTY ACNAARMGNAARTTYGGNYTNATGAARAARGCNTAYGARYTNAGYGTNYTNTGYGAYTGY GARATHGCNYTNATHATHTTYAAYAGYTCNAAYAARYTNTTYCARTAYGCNAGYACNGAY ATGGAYAARGTNYTNYTNAARTAYACNGARTAYAAYGARCCNCAYGARAGYMGNACNAAY AARGAYATHATHGARGCNYTNAAYAARAARGARCAYAARGGNTGYGARAGYCCNGARGAR CARGAYCCNTAYGGNGGNGGNYTNMGNCCNGAYGAYAARTAYGAYMGNATHCCNGAYGAY TAYCARMGNGCNATGCARCARAAYGCNGTNMGNCAYTCNATGCARCARTAYCAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CAYTTYGCNMGNGARTGYAAR ATGGGNATGGAYMGNTGYTAYAARTGYAAYCARYTNGGNCAYATHGCNAAYGARTGYGAY AARGARATHGAY------GCNGCNTGYTAYAAYTGYGGNAAYCCNGGNCAYGTNCARMGN GARTGYCCNGAYCCNAGYAARMGNTCNTGYTAYMGNTGYGGNGAYAGYGGNCAYYTNGCN MGNGAYTGYACNGARCCNCARCAR------------ATG------------GAYGAYMGN AARTGYTAYACNTGYGGNCARMGNGGNCAYYTNTCNMGNGAYTGYACNMGNAGYGGNGGN AGYGGNGGNAARGAYTGYTAYMGNTGYGGNGCNTCNGAYCAYYTNGCNMGNGAYTGYCCN CARGCN---GCNAGYMGNACNCARTGYTAYAAYTGYAAYGARATGGGNCAYATGGCNMGN GAYTGYCCNAAYGARTAYYTNCARGCNAGYGGNGCNGARAARTCNAARGCNYTNCARGAR ACNAARGAYTAYACNACNCAYTCNYTNGCNAGYGTNGCNTAYCARATHAAYAAYYTNGCN ACNAAYTTYYTNAARYTNYTNGAYYTNCARCARGGNCARYTNACNGAYATGGARAGYAGY GTNAAYCAYYTNGCNCARATHGTNATGATHCAYAARGARAARGTNGCNMGNMGNGARATH GGNGTNYTNACNACNAGYMGNAGYGTNCCNMGNCCNYTNGAYATGAARAAYGGNATHATH TAYCCNMGNCARACNGARMGNCCNATHAARTAYACNMGNAARCCNATHGAYTAYTCNGTN YTNGAYGAYATHGGNCAYGGNATHMGNGCNCARTCNAAYACNCCNMGN---------ACN GGNMGNAGYCCNAGYGTNAGY---------AGYAAYAGYTCNGCNAAYAAYACNCARGCN CCNACNACNAARCCNCCNACN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNYTNMGNTCNATHCAYAAY TTYGARGARAARATGAARATGATHATHCCNCCNAGYGAYGARGGNGAYGARATHGAYATH CARTAYATHATGTCNMGNGAYGARGARMGNGGNGARCCNATHCAYATGYTNAARGTNACN TCNAAYGAYGAYTAYATHGGNAARATHMGNMGNMGNYTNGARGARGAYGCNGCNGCNMGN GARGARMGNGARAARMGNMGNMGNAARGTNYTNGGNGAYCARYTNATGGCNCAYCAYGCN CARGARGARGCNMGNMGNGARGARATGYTNGCNAAYMGNYTNATGMGNCARTCNCARCAR GARMGNMGNATHGCNGTNCARYTNYTNCARGCNMGNCAYGARAARGARGTNATHMGNCAR AAYMGNATHTTYMGNGARAARCARTAYCARGAYMGNMGNYTNAARGAYTTYGARGAYGCN YTNGAYMGNGARGCNGARATGTGYGCNYTNCAYAARATGGARTAYCARGCNCARATHAAR GCNGAYCARGARYTNCAYGAYCARATHGCNGCNMGNMGNGCNGARATGMGNTAYGCNAAR CAYTAYGAYATGTGYAAYGAYATHGTNAAYAGYATGGTNGAYTTYTCNTGYAARGTNGCN GARTAYMGNGARYTNACNAAYAAYYTNYTNCCNGCNAARYTNATGMGNGARTGGAARYTN YTNTTYATGGARGGNAARCCNYTNTAYGARGTNGTNGARGTNGARACNACNGARCCNACN CCNGARCARATHYTNGARGARGARMGNCARCARYTNYTNGAYGARGGNGAYTTYATGGAR TAYAARACNATGAAYGGNGARTGGCARCCNCCNGAYGGNAGYGARATHACNGGNCCNCCN MGNGAYAAYCCNGTNGTNCCNCCNACNCCNCCNCCNCCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARATGGCNAARGARGAR------AARTTYATGGARAARYTN GGNGARYTNCCNATHGTNACNGAYTCNTGGAAYYTNGCNACNGAYTAYTAYGARCARACN AARGCNTAYAGYTCNYTNYTNMGNGCNACNYTNAAYATGGCNGARACNGGNGCNAARGCN GCNCARAGYTTYAGYTCNCCNATHATGGARMGNTGYCARGAYCAYATHGAYTCNGTNAAY AGYTTYGCNTGYGAYAARYTNGARAARYTNAARAARGAYTAYCCNGTNATHACNAARCCN ACNAARGARGTNGTNGAYCARTAYAGYGARTAYGTNGARCCNGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNYTNGGNATGACNTCN MGNCARGTNTTYTGYTTYAARCARTCNTGGAARGGNATHAARMGNAARATGGARGAYACN GGNGTNGARATGTTYGTNMGNYTNTTYAARATGAAYTCNCARYTNAARGGNATGTTYGAR AAYTTYAARGAYATHGARTCNGAYGAYGARYTNMGNTCNAAYGARGCNYTNGARTAYCAY GCNACNYTNGTNATGACNACNYTNGAYGAYGCNATHGCNCAYATHGAYAAYTTYGAYTAY GTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGTGGTTYATHATGGARTCNACNCARCAR AARTAYCARYTNTCNGAYMGNYTNATHMGNGCNATHACNAAYTGGTCNTTYTCNACNATG GAYGAYGAYATHGARGARYTNATHCARYTNGGNGCNGAYGTNAAYGCNGTNCAYGGNACN YTNYTNCCNYTNCAYTGYGCNTGYATGTGYAGYGAYAGYTAYTGYYTNAARYTNYTNYTN CARAARGGNGCNMGNGTNAAYGARGTNGAYGGNTAYGGNMGNACNGCNYTNCAYTAYGCN GCNGARMGNGAYATHTTYTGYGTNGARATHYTNYTNCARCAYGGNGCNGAYGTNGAYGAR GGNGAYGGNAAYAARGAYACNCCNYTNCAYTGGGCNTCNTTYAARAAYAAYGTNCCNTGY GTNAARYTNYTNYTNCARCAYGGNGCNGAYGTNAAYGCNACNGAYTTYAAYAAYGAYACN CCNYTNGCNTGGGCNGCNMGNAARGGNCAYYTNGARGTNATHAARGTNYTNYTNGARTAY AAYGCNGARGTNGAYACNMGNAGYYTNACNGGNCARACNGCNYTNCARMGNGCNGTNAGY GTNCARGCNTCNGGNYTNAAYAAYGCNGCNGAYGAYGCNTGYYTNGARYTNYTNATHMGN GCNTCNGGNCARTTYGAYYTNTGYCAYYTNCARGGNGGNGGNYTNMGNGARATHCCNCAR GAYAAYMGNYTNAGYGARYTNYTNMGNCCNTAYTGYGARMGNCCNMGNYTNYTNCARGAY YTNTGYMGNMGNTCNATHMGNMGNGCNYTNMGNTGYCARTAYYTNCCNAAYGTNGTNCCN AARYTNMGNYTNCCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TCN YTNYTNYTNATGYTNCARGTNTTYTAYGGNACNATGGCNACNTTYCARYTNCCNCCNTTY YTNCARACNGCNGAYCARCAYTCNGAYMGNGTNTTYGCNGTNCARAAYGTNGAYATHMGN AARTTYACNCCNMGNAARAARCAYYTNAARACNCARMGNYTNYTNMGNMGNATGGGNGAY CAYATGGAYCCNTTYTGGATGTCNGTNGAYATGCCNGGNGAYYTNYTNGAYACNACNGTN MGNMGNACNYTNGAYTCNTCNYTNGTNGARCARGCNGCNGCNYTNGAYATGACNGGNYTN ------------------------------------TTYAAYGAYTCNTCNYTNTGGMGN ------ACNTTYGGNGAYTTYMGNGAYACNGGNGTNAAY------GARACNGTNYTNGCN TCNATGTTYCARAARTGGYTNGCNMGNAARTCNTCNTGYCCNGTNTAYTAYACNTGGGAY GAYYTNGGNYTNYTNTAYTGGCCNMGNTGGGTNMGNMGNGGNTCNTGY------------ ------------------------------------TCNMGNACNTCNGAYTCNGCNTCN CCNGAR------TCNTGYTCNTGGCCNCCNGGNATGCAYTGYGTNCCNGCNAARACNAAR MGNATHAARATHYTNMGNTGGCARTGYMGNAAYAAYAARGCNTTYAARAGYTTYAARMGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNTCNTGGGTNCARGGNTGGAAYGCNMGNTCN MGNGAYTTYGGNCARAAYTAYGARGARAARGAYGTNACNATGGARYTNGGNGARGARCAR GAYGAYGARTTYMGNATHGARACNGTNYTNGTNGAYAAYGARGTNYTNGAYGTNGGNCCN TAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHAGY TTYATGAARATHATGAARGCNGCNAGYTAYYTNAARAAYCCNAAYATHYTNTTYYTNGGN ACNAAYGAYGAYCCNACNYTNCCNAAYMGNAGYCAYGTNGARATHCCNGGNACNGGNACN ATHGTNAARTCNGTNATGGTNCCNTCNGGNMGNAARCCNAARYTNYTNGGNAARCCNCAY ACNGCNATGTTYAAYGTNYTNAGYGCNACNCAYGGNYTNGAYCCNGCNMGNAGYYTNATG ACNGGNGAYMGNYTNAAYACNGAYATHGCNTTYGCNMGNAAYTGYGGNATGAARTCNTTY YTNGTNYTNTCNGGNAGYACNACNATGGARGARYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GGNGAYMGNGAYGGNGARMGNGGN------GGNMGNAAYMGNCCNMGNGTNTCNMGNTGG GARCCNGARGARAAY---AAR---------GARGARTAYGAYCCNTCNMGNCCNACNGAR GAYGARGGN------GGNGAYCCNGAYMGNAAR---TAYCARTTYTTYTGYCAYGTNTGY AAYGTNGGNGTNTAYGAYGARCCNAGYTTYAARMGNCAYYTNAAYGGNGTNAARCAYGCN GARMGNATGAAYAGYGTNYTNTCNGTNCAYGARGCNACNTCNAAYCARYTNAARTCNMGN ATGAARGCNGARGARCAYYTNMGNAARATHGARAARMGNGGNGGNMGNGAYCCNGAYTTY TTYTGYAARATHTGYGAYMGNGAYYTNACNATHCCNTGGACNACNCAYMGNGARTCNACN YTNCAYMGNAARMGNGARGARCARGTNMGNAARGGNTGYGGNTGGTGYGGNGTNCAYAAY TTYAARAAYTTYTCNGAYGTNYTNGCNCAYMGNGAYACNGARAARCAYAARATGAAYGCN GCNGARCARAARGARAARGARAARGAYGGN---GAYAARACNCCNAARTCNGAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GTN ACNATHCCNAAYTCNAARYTNCCNAGYGAY------------GGNTAYGAYTTYTCNCCN TAYGCN---GGNAAYTCNCCNAAYACNAGYTTYGGNGCNAGYTCNGAYTAYMGNCCN--- MGNCARGARGGNAAYAAYACNATGATGAAYMGNAARGTNTTYATHGGNMGNGTNACNGAR GAYATHAGYGCNGAYGAYYTNMGNAAYTAYTTYAAYAARTTYGGNGARGTNGTNGAYGTN TTYATHCCNAARCCNTAYMGNGCNTTYGCNTTYGTNTCNTTYGCNGAYCCNGARGTNGCN CARTCNYTNTGYGGNGARGAYCAYATHATHAARGGNGCNAGYGTNCAYGTNAGYAGYGCN GCNCCNAAR---TCNTTYGAYAARGGNGAYGGNMGNAARGGNTAYAGYCAR---GGNTAY AGYCARGGNGGNTGGGGNCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GTNGCNMGNYTNCARATGCARYTNTAYAARAGYYTNACNMGNATGCAY AAYMGNGCNGARGTNCARGAYGCNYTNAGYMGNYTNAAYGCNGAYYTNYTNGAYATHACN ACNYTNTAYGARGAYTTYGCNGAYMGNTTYGARYTNCAYGARATHAARYTNGCNATHATH CAYTGYGCNGCNYTNTAYGAYGCNGCNYTNATHGARAGYYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TTYGGNMGNTAYGAYGAYCARTAYGGNACNTCNTCNGGNATGTCN GAYYTNYTNAGYTTYACNCCNTCNACNCCNAGYCCNGARTCNATHAAYTGYCAYGTNGAR GTNCCNGTNATHCARMGNGTNGGNGGNMGNTGYGTNCCNYTNGGNGARMGNATGGCNTGY CARGCNGGNATHCAYYTNGCNGTNAAYTCNGAYTGYATGAAYCCNTCNMGNGGNCAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYTTYGAYYTNCCNGTNTCNAARAARCARTGYGARGARAARYTNMGNGARAAY TTYYTNAARAAYMGNCAYGTNACNGAYGTNMGNACNATHGAYYTNYTNYTNATHAARGGN CARATGGARYTNGTNGARACNGCNAAYATHTGGAARCARMGNAAYCAYATHATGATGTTY TTYAARGAYACNGTNAAYCCNAARCCNGCNGAYMGNAARAGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TCNAGYGCNGTNAARGCNATGCARAAYAGYACNATHCAY TTYCARAAYATHCARGAYYTNYTNAARAAYGCNATGTTYATGAARCARCARATHGARTAY GARGAYACNMGNAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AGYAAYAGYCARGCNGAR ATHAARGAYCAYTCNGGNMGNGARCAYCCNGGNAARCCNCAYMGNTAYGTNGCNYTNATH MGNAAYATGCAYCCNGCNATGTCNAGYACN---AAYTCNTCNCCNYTNTCNCARTCNCAR GTNTCNAGYCARTCNTGYTAYYTNCCNGCNACNAARACNATHTCNGCNCCNTCNTCNYTN CARAAYTCNTGYAAYTCNATHTCNTCNGARGARAAYTCNCARGAYATHGTNTCNYTNTGY GAYGAYTCNGGNGGNAGYAAYGTNYTNAARGTNAARYTNGTNCCNGCNTCNTCNAARAAR GARACNATHACNTAYMGNTGYTAYCAYTGYTCNTAYACNGGNMGNMGNCAYTCNTCNATG AARACNCAYATHYTNTAYAARCAYMGNGGNAARGGNYTNGTNGCNGTNGAYGARACNTCN GAYMGNGGNGAYCARGTNTAYTTYTGYGCNMGNGAYGAYTGYACNTTYAARGAYAGYMGN CCNTCNTCNTAYYTNGCNCAYGTNGARMGNTGYACNCCNTGGAAYMGNCCNGAYYTNTCN GAYGTNGARGTNGARCCNCAYATHMGNGARTGYYTNCARCARACNYTNACNTTYGCNCAR ATGGCNAGYAGYAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TGYYTNCCNTGYAGYGTNYTNATHGGNGTNACN GTNMGNTCNAARAAYGGNGTNTGYTGYACNAAYAAYAARGTNCCNGGNTAYGAYGGNGCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MGN GCNGCNCARGAYGARCARATHMGNYTNAARGAYATHGARGTNAAYGARYTNAARTCNGTN MGNATGGAYYTNGARAARGARTAYMGNGAYGCNMGNACNATHGCNGAYAARYTNGCNGCN CAYYTNYTNTCNCARGAYCARGCNCARCARYTNCARCARGARTTYTCNGAYYTNAGYTCN ACNAARGCNGGNYTNGCNGCNCARYTNTCNGARGCNCARGCNAARATHCAYGAYYTNMGN CARGCNYTNGTNGARTAYCARCAYMGNGARAARGGNGCNAARGARGARGGNGARYTNTAY AARAARCARYTNTAYCARGARMGNAAYGGNYTNACNAARGAYTAYGARACNYTNAARCAR GARYTNAAYGARGCNAARGTNMGNGARGCNCAYACNATGCARGARYTNAGYMGNAARATG AARMGNGAYCAYGCNGARCAYGAYGCNGTNATHCARGCNYTNAARATGGARYTNTCNGAR GARAARTCNAGYGCNAARATHGCNMGNMGNAAYGARCARAARYTNAARGARGARYTNGAR ATHYTNGARAARAARYTNAARATGTCNGARGARGARAAYTCNGGNATGMGNYTNAARATG GARGCNGTNAARCAYGARTTYGARGCNCAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARMGNGARCAYCAYAAYGCNYTNGARMGNAARMGNMGN GAYTGYATHAARGAYAGYTTYCARAAYYTNMGNGAYGTNGTNCCNATGYTNTGYAARGAR AARAAY------------GARAARGTNTCNMGNGCNAAYATHYTNAARGGNGCNGCNGAY TAYATHGARAAYYTNCARCARGGNAAYTCNCAYCAYGARGCNGAYATHMGNTCNYTNGAR AARCARAAYCARTCNYTNMGNGAY------------------------------------ ------------------------------------------------------------ ------------------------------AARATHAAYYTNYTNGARMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYGCNGCNCCNGARMGNTCN YTNTCNACNTGGTTYGCNGARGTNYTNGARYTNMGNMGNMGNGCNAAYGARTAYMGNAAR MGNGCNCARGGNACNCAYTTYTCNMGNGARCAYYTNGTNCARYTNATGGCNAARCARGCN GARTGYTGGGAYYTNCARTCNGARGCNTCNTCNACNGTNMGNGCNYTNGAYYTNGARACN MGNCCNGGNCAYAARAARAARGCNGCNGAYGTNYTNGARGAYYTNGARGAYGARGAYYTN ATHGAYGCNTAYTCNAAYAARGCNACNTCNGGNGAYGGNGAYGGNAGYGGNGAYGTNYTN CARGARGCNCCN---AARAARGCNGGNAARAARAGYAAR------AARGARGGNAARAAR GTNAARGGNMGNAARAGYMGNAARATGGCNTGGYTNGARGARCARAGYGARAARGTNTCN CARCARAARMGNAAYYTNGARGARGARMGNCARMGN---------------ATGCARGAR GGNGGNGGNGARGGN---GTNGAYGARGARGGNMGNYTNCCNACNCCNCARYTNMGNCAR CARGCNGCNAARGCNMGNMGNCAYCAYYTNGAYYTNACNACNCCNGCNATHGGNGGNGCN YTNYTNACNTGYCCNCCNTCNGGNCAYAAYAARATGYTNGTNACNTCNMGNTCNGGNGAY AGYTAYGTNACNGCNTCNGAYGAYGCNCCNGTNGCNMGNAAYGTNAARCARTAYGAYATG AARCARYTNYTNACNATGCCNYTNYTNGGNAARCCNTCNGGNGAYACNCAYCCNYTNMGN GAYGAYTCNGCNGARGARGAYMGNCCNYTNAGYACNGTNTAYATHAGYTCNCCN------ ------GCNCCNCARGAYAARGARTGYTAYCCNGAYGTNTCNAARACNAGYCARAARAAR MGNGARGGNGGNYTNGGNCCNATHMGNGARGGNGTNGGNGARACNTAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TGGCARATHAGYCARAGYCAYATHMGNMGNYTNGAYAARCARGARYTNGTNTAYCARCCN ATHACNGTNACNGTNACNACNGAYGARATHGGNGCNATHGARTGYMGNACNTAYMGNATG ---------GCNAAYAGYMGNGAYTGYYTNACNAGYCCNTTYTAYAARGARGTNYTNATG AARGGNGCNGCNGAYGTNCARYTNCCNCARAGYTAYATHGAYTTYYTNGAYAGYTGYCCN ACNAAYGARYTNAARGARCCNCCNTCNGTNTAYGTNAAR------------------GGN AAYAAYMGNTGGYTNCAYCCNGARGAYGCNYTNYTNAARGGNCAYATHYTNTAYACNGTN AARTTYYTNGGNGARTGYTCNGTNGAYCARCCNAARGGNYTNGAYGTNGTNAARGARGCN ATHMGNAARATGAARTTYAAYAARCAYATHAARMGNGCNGARGGNCARAARCCNCCNAAR GTNGARYTNACNATHTCNGCNGAYGGNGTNGCNGTNACNGAYCCNAARACNAARGARGTN AARCAYCARTAYCCNYTNCAYMGNATHTCNTAYTGYGCNGAYGAYAARTCNGAYAARMGN ATGTTYACNTTYATHGGNAARGCNGCNGAYTCNAAYAAYCAYTTYTGYTAYGTNTTYGAY AGYGARAARTGYGCNGARGARATHACNYTNACNGTNGGNCARGCNTTYGAYYTNGCNTAY AARMGNTTYYTNGARACNACNGCNCARGAYTCNGAYATHAARAARCARTTYYTNATHYTN CARAARMGNGTNCARACNYTNCARTTYGARAAYGARGARYTNMGNAARMGNYTNGCNCAR ATGGARAARYTNAARGAYMGNGGNGAYGTNGARAAYTAYATGAARAAYAAYCARATHTCN AAYYTNTCNGCNGTNAGYTTYAAYYTNMGNGARAGYTCNACNGAYGAYGAYGAYGGNGAY TTYNNNNNNNNNNNNNNNACNCARAARCAYGCNGTNGTNGGNMGNMGNYTNGARAAYYTN YTNYTNAGYGAYGAYGCNCAYCAYAAYCARCCNGCNAGYCCNACNAGYACNACNAAYGGN AAR------------------------------ACNTCNATGCCNGTNYTNAGYCCNCCN CCNCCNTCNTCNMGNGGNCARMGNTCNAAYTCNAGY---------------AGYACNCAR TCNCCNCARACNCCNCCNGGNAAYCCNTTYGCNGCNAGYCCNCARTCNGCNTCNACN--- ---------GAYCCNTTYGGNATGTCNGTNTTYAGYCCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MGNGGNACNAARMGN TCNMGNGAYGARTTYGARGCNACNTCNGGNAARGARTCNACNCCNGARGCNTCNCCNCAR AARAAYAARAARMGNTGYTAYAARTGYAGYGCNAARYTNGARYTNGCNCARMGNGARATH GGNMGNTGYMGNTGYGARYTNATHTTYTGYGCNYTNCAYMGNYTNCCNGARYTNCAYCAR TGYGARTTYGAYCAYAARGARGAYGGNMGNMGNGARGCNMGNGARAARATGGTNAARCCN ACNMGNCAYYTNGGNACNTCNTTYMGNMGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGGAR GTNATGTCNACNACNGCNYTNATHYTNGARGAYMGNCCNGAYCAYYTNCCNTCNAARTCN AARGARGARGCNGARAARCAYAARYTNCARTAYGARGCNATGGTNGARGCNGCNAARAAR AARGARCARAARGAYYTNAARYTNMGNAARAARYTNCARCARCARMGNMGNCARGARGAY CARYTNATGGCNGCNTCNTCNGTNTGGAAYAARGAYATHYTNCCNAAYTGGGAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY GTNTCNTAYTCNGGNGARAARGTNGGNATHGGNCAYATGTGYYTNTGGTGYAAYYTNCAR GGNAARGCNTTYGCNACNGCNMGNGAYGTNCARAARCAYATGACNGAYAARGGNCAYTGY AARGTNAAYTAYGAYGGNGAYGCNATGYTNGARTAYTCNGAYTTYTAYGAYTAYTCNTCN AGYTAYCCN------GAYAGYACN------GARGGNMGNAARGAY---GAYGARGTNAAY CCNGTNGTNYTNGAYACNGAYGGNTAYGARYTNGTNYTNCCNTCNGGNGCNACNATHGGN CAYMGNTCNYTNCARMGNTAYTAYCARCARAAYYTNMGNCCNCARCCNAARTCNGGN--- ---AARYTNYTNCCNAARATGYTNTCNCARTAYMGNGCNYTNGGNTGGACNGGNAGYGCN GGNCARGARGTNCARACNMGNGTNAARGAYATHAARTTYATGCARMGNYTNMGNAGYMGN TAYCAYATGCARYTNGGNGTNAGYAAYAAYGCNYTNMGNCAYMGNYTNMGNGAYCCNAAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CCNCAR GCNYTNCARCARGCNTGYGTNMGNACNTTYGGNCAYYTNATHTCNYTNGAYMGNGAYGCN ATGTGGYTNYTNYTNGCNCAYACNTTYTGYCCNGTNACNYTNGTNCCNCCNGGNGARGGN TTYACNCCNGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TCNCCNAGYTTY AAYGAYGCNGCNGCNMGNGCNATHYTNACNACNTGYGTNTCNAAYTGYGCNACNATHATH ACNGTNGGNATHATGAGYMGNCCNCARAAYYTNGGNACNATHCARCCNACNGAYACNGCN GCNAARGGNYTNMGNGCNACNAGYTGYAARGTNAARAAYGARGCNATHGAYYTNAAR--- GCNGGNYTNCARAAYATHGTNMGNGTNCAYAARGTNGAYGCNACNGCNACNGARCARGAR MGNYTNGARGTNAGYGTNMGNATHGARGAYTCNCARTGYATHTCNGTNGGNGARATHAAR MGNTGGCARTGYGARCARTGYGAYAARTCNTAYACNACNAARCAYAAYYTNGTNATGCAY ATHYTNGAYCAYTAYAGYATHAARCCNCAYYTNTGYYTNGTNTGYGGNAARTAYTTYAAR CARYTNAGYCAYYTNAAYACN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CCN GCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAARAARNNNNNNYTNAAR MGNGCNCCNACNGCNTAYATGYTNTTYTGYAAYACNCAYMGNCARAARATHGTNTAYCAR AAYCCNGGNATHGAYTTYGCNCARATHAGYMGNAARYTNGGNGTNATGTGGCARGARYTN TCNAGYAARGARAARYTNGCNTGGMGNMGNAARGCNAARAARATGGCNGGNAARTCNACN YTNATHTCNACNGGNAARGCN---ACNAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TCNGARYTNGGNGAYTTYGAYAGYMGNGTNCAY ACNCAYGGNTAYGTNTCNGARTTYTGYTTYGTNCCNAAYCARACNGARGARGTNGARAAY MGNATHGCNGCNTAYCAYMGNMGNTGYYTNGGNGCNACNCCNYTNATGGCNGARCAYMGN TTYYTNGARAARGTNAARTGGYTNGARATGTAYGGNGTNGAYYTNCAYCCNGTNCARGGN GARAGYAAYGTNGARTAYTTYYTNGGNYTNACNCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TAYGGN---CCNCCNCCNCARGGNTAY GGNTAYGGN------------------CARCCNTAYCARCARTAYCCNTAYCCNCARCAR CCNTAYACNCAYCARCCN------------------CARCARGTNGTNTAYGTNMGNGAR GARMGNMGNAARAGYMGNGAYGAYMGNACNGCNGARACNTGYTGYYTNATHGGNYTNTGY AGYYTNYTNYTNTGYTGYTGYATGATGGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GGNCARAAYAARTTYMGNCAYGGNTCNYTNGAYAAYGAYTAYTAYGGNCCNCCNCCN CAYTTYCCNTTYTAYGARCCNCAYTAYAAYTAYGAYAARATHTCNATGCCNTAYAGYTCN CARCARAGYYTNYTNMGNTCNAAYAGYMGNGAYAGY------GGNMGNCAYTAYTCNACN AARGGNGCN--------------------------------------------------- ---AARMGNGCNAGYCAYGAYMGNGAYMGNGAYGGNMGNAARGAY---TCNGGNGGNGAY GCNMGNGGNAARGAYMGNGAYGGNGARMGNGAYMGNCCNTAYAAYGAYGAYTTYCCNTCN YTNAAYGGNAGYGCNGARCCNGCNGAYGTNAARAARCCNAARTCNACNTCNGGNGTNTGG GAYAAYCCNCCNAAR---TCN---AAYMGNAAYGARGAYTCNTCNGAYYTNYTNAARAAY TCNTCNCCNAAYATHTAYAARGCNYTNGTNCCNAAYAARAGYGGNTCNGCNMGNAARATH GGNAARGARGGNGTNMGNYTNAAYGGNAGYATGMGNGAYTCNTCNCCNYTNTCNCCNYTN CCNTCNCARTCNGCNAARGAYGGNACNMGNCARAGYCCNACNCCNGARATHCCNYTNGTN ATGCARCCNAARAARYTNGGNGAYAARMGN---GAYTTYYTNAARGCNYTNMGNAAYGAR AGYTCNGCNAARAAYGTNGARAAYGTNGGNGARCARAAYCAYAGYTCNAAYGGNGARAAR CARYTNAAYGGNGAYTCNGARATGCARCCNCARCARGTNCCNGTNAAYGGN---GARTAY GTNAAYGARAAY------------------------------------------------ ---------------------GGNYTNGTNAAYGGNGTNGAYCAYATGACNYTNTCNTCN ATHACNGARCAYGGNAARTGYATHTCNGCNCARGAYGARGAYMGNYTNYTNAARYTNATG GGNTGGAAYGARGAYGAYGAYACNGAYTAYAGYYTNACNACNGARGARATHGARAARTGG AARAAR---GARCAYGARATGGCNAGYAARCARMGNAAYGGNYTNAARMGNACNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TAYCCNMGNGARTAYAAYCCNAARATHCAYGGN CCNTAYTAYCCNTTYGTNTAYTAYGGNAARMGNGAYATHCCNYTNGGNGAYGTNAARTTY GGNGARYTNGGNCARTGGGTNTCNMGNMGNAGYTTYAAYCCNGTNGAYTGGTGGMGNGCN GCNTGGMGNAGYTAYCAYAGYTTYCARTTYCAYMGNTAYTGYGCNMGNMGNTCNAGYYTN GCNCCNATGTTYCARYTNYTNGCNATGTGGAGYATHTTYTGYTAYTTYGCNACNTAY--- ---------ATHCARCARGAYTTYGAYGCNACNAARGAYGAYYTNGAYGCNACNMGNCAY GAYYTNGCNGARAGYMGNCARTCNATHGTNGAYYTNAARGCNACNATHGCNGGNYTNAAY GAYGAYYTNAAYAARTAYMGNAAYYTNCARGARGARACNTCNAAYGAYYTNMGNMGNCAR GGNGARCARYTNMGNGARCARGARATHATHYTNTCNGARACNMGNCARCARYTNGTNGTN ACNCARAGYCARYTNGAYGCNAGYAARGARGAYGTNAAYAGYYTNACNCARTCNYTNAAY ACNACNAARCARAARTAYCARCARGCNGCNACNGARGTNACNCARYTNGARTCNACNATH GGNAGYYTNCARGAYAARYTNACNCARAGYMGNAGYTCNGARYTNGAYAARGARGCNACN ATHGARCARCARMGNTCNGARYTNGARGGNYTNGAYMGNGCNTAYAGYGARACNAARGAR GARATGGCNAARTGYGARGAYATGATHCARCARYTNACNGAYGARYTNGGNMGNTCNCAR GCNGARYTNGGNAGYGCNCAYTCNMGNATHAARGARGGNGARGARGTNATHMGNGAYYTN AARGAYMGNYTNCARGAYTCNCARCAYCARGCNYTNCARAAYGAYGARAARGCNCAYAAY TTYGARAAYAARYTNYTNACNTAYCARGCNGARCAYAGYCAYTCNGAYMGNGARTTYYTN CARAARGARGARYTNATHAAYTCNYTNGARTAYGAYYTNGARGGNGCNMGNGCNGAYYTN CARTGYAARGCNMGNAARATHACNGARYTNACNTCNGAYYTNGGNAARACNGARGCNGAR YTNACNAARACNAARGARGAYAARAGYGCNGCNCAYGGNACNATHGAYMGNYTNGARCAR AGYATHCARCARYTNCARYTNAAYYTNAAYTCNGCNCAYCARMGNCAYAARAGYGARTGY TGYMGNTAYGAYGAYCARGTNGCNACNYTNGARMGNMGNYTNGCNGARACNGARAARAGY YTNCARGARGCNGARTGYGARATHAAYAAYAARGARGARAAYATHAARMGNAAYGARGCN GARATHGCNTCNTGYMGNGAYGAYATHMGNTCNAARGTNGARGARATHGARAARYTNGAR MGNAAYATHCAYGAYYTNAARGTNGARATGAAYCAYYTNAAYATGCARAARGCNAARTGY GARGARAAYATHTCNGARYTNCARAAYGARACNGARAAYYTNMGNGGNGAYYTNGCNGAR GCNMGNTCNCARTAYAARGAYTGYGCNCARGARYTNGCNCAYCAYGARGARAARYTNATG YTNATHGARCARAGYYTNCARTCNACNCARGAYCARYTNAGYCARMGNGTNACNGARATH GTNMGNCAYGARCARAAYACNMGNAARYTNCARATGGARGTNAARACNYTNMGNGARMGN TGYGARAGYTAYGARGARGARATGGCNGARCARAARTCNCARATHGAYMGNYTNMGNAAR GARYTNATGGGNACNAARGARGARTAYCAYGCNTCNGTNCARGARGGNATGGCNTAYAAR CARCARGCNAAYAARYTNGARGTNGARYTNGGNGGNTCNMGNGARCARGARAARATGYTN ACNGAYCARGTNGARCARCARGARCARATHYTNACNCARYTNCARAAYGARYTNMGNGCN GARMGNGAYMGNCAYTCNGARACNGGNMGNCARYTNGCNGTNAGYAARAARCAYGCNGTN GAYATHCARTCNGAYYTNGARGCNATGACNAARAAYGTNMGNGARYTNCARGAYMGNGTN AARACNMGNGARGARCAYATGGCNMGNCARMGNMGNGARATHGAYGAYYTNCARCARAAR AAYMGNGARACNAGYGARATGATGGCNGARMGNGARGGNCARYTNMGNGTNGCNAAYATG AAYYTNGCNACNGCNCAYAARCARGCNCARCAYCAYACNCARGARATHGCNMGNTAYGAR GAYATGYTNGCNCARYTNCARTCNGARCARGARAARYTNCARGARCARTAYMGNAARTCN AAYGCNGAYYTNATGGAYGCNGAYAGYAARGTNCAYGARYTNAARGTNCARYTNACNACN GTNCARGGNAAYCAYAARGARGCNATGGAYCARYTNGGNGARAARTCNMGNTCNYTNGCN GCNGTNAARACNGAYATGGCNAARYTNTCNCARCARAAYAAYTCNATGAARGARGARATH ATGTTYTAYGAYGARAARYTNMGNAARYTNCARCARGARYTNAARAARATGCARGARYTN AAYMGNGCNACNGARGARGARYTNCARCAYTTYGARGARMGNTAYACNAGYYTNCARGTN GAYYTNGTNTCNAGYCARGARAARCARAARCARGCNYTNCARGARYTNTCNAGYAARGAR GARGARATGGTNGTNYTNAARGTNGARYTNAGYTCNYTNCARGARAARTAYAARAAYGTN ACNGAYGARAGYACNAARYTNMGNAAYGARYTNGARYTNATGMGNCARAAYTAYMGNAGY GCNAAYGARGARATHTCNGGNYTNMGNGTNGCNYTNGARGARTCNMGNGCNAAYGGNGAY MGNYTNCAYMGNGARAGYGARYTNGTNGTNCAYAAYGTNAAYACNTGGGTNCARGARCAR AARYTNGCNAAYGARAARYTNGGNAAYAARATHMGNGARCARAGYAARGCNATHATGGTN YTNACNTCNGARAARGARTCNYTNYTNGARCARATHCARAARYTNCARAARACNTAYAGY AARACNAARGCNGAYYTNGARGAYAARGTNACNGARAGYGARAARYTNMGNGCNYTNCAR TCNCAYTCNGCNCAYCARCARGTNATHYTNAAYCARYTNAARAGYMGNYTNGARGARCAY GARGTNGARCARGAYGCNGAYYTNAARACNAARGTNGCNACNATHGARGAYYTNCAYGCN MGNYTNAARTCNAAYATHGARAAYGTNCAYCARYTNAAYCARCARYTNAGYAGYYTNCAR AARGAYAAYGTNMGNYTNMGNGGNGARYTNGARMGNGARATHTCNGCNMGNCARAAYYTN GARATGCARATGCARACNAARGAYCARATGGTNGARAGYYTNMGNTCNCARYTNGAYAAY TCNTCNTAYMGNMGNYTNYTNGARCARGCNGAYAARTAYAARGAYCCNGARAARYTNGCN MGNTCNGCNATHAGYAARGTNYTNGARGAYACNGGNGTNAGYGAYCCNCARCARYTNGAY AARTCNTAYTGGATHCARMGNGTNGGNGARGCNCARYTNTCNGTNCARYTNCARCARAGY AGYGAYTAYTGGTCNGAYAARGTNMGNGARYTNTCNGGNCARYTNGARAARGCNMGNGTN GCNAGY------GTNACNTAYYTNYTNAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AGYCARTTYTAYAGYAARGARAAYGGNCAYGGN GARYTNGTNGTNMGNAARMGNTCNAARGGNCARMGNGAYMGNYTNMGNYTNYTNMGNCAR GGNAAYMGNMGNTAYACNGTNCARGGNYTNGAY---------AGYTAY------GTNGGN GGNYTNTAYGAYGAYAGYYTNTCNGARCCNAGYGAYTCNTCNAGYMGNGARGTNCCNGAR GAYYTNATHTCNGTNTAYAARAAYATGACNAARGARGARYTNATGMGNGTNGTNATHCAR ACNAARGCNCARATGATHMGNAARGAYCARTAYATHAARGAYYTNGARAAYTAYATHGAY GAYYTNYTNGTNMGNGTNATGGARGCNACNCCNMGNYTNYTNAGYMGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNCAYCCNGTNACNGCNCCNYTNMGNGARMGNAAYGCNTAYAGYGCNAGYAAYGTNGCN CCNYTNGGNTCNAGYGCNGCNACNGAYAARAAYGGNMGNCAYCAYTCNAARAGYAARTCN GARATGAGYTTYTTYAARAARTCNYTNGCNTCNTTYMGNGGNATHACNMGNMGNAAYTCN TCNMGNAGYAARACNTTYGAYAARYTNAARCARCCN------------------------ ------------CARGARGGNGARAARTCNCCNACNGARAAYCCNMGNGARAARMGNCCN GCNAARCCNAARMGNMGNAGYTTYAARTTYCAYTCNAARGAYGARACNAGYGARMGNAAR CCNAGYMGNMGNGARGAYAARTCNTGGTTYTCNGAYAAYGAYACNMGNGAYGGNAGYCAR ---------------TCNTCNGGNGGNYTNCCNMGNYTNTCNGCNTCNGARAAYMGNAGY MGNGARTGYTCNGTNGARAGYTGYTCNTGYMGNATHGGNGGNTCNACNTGYMGNGARMGN GAYTTYTCNGGNTTYGAYTCNACNTCNYTNTCNGGNTAYGAYTCNGAYTGYCCNMGNTAY AARGTNMGNMGNTCNMGNTCNMGNATHAARACNAAYCCNTGGYTNCCNTCNCCNCARCCN TCNGCNTCNACNACNMGNMGNGARATGATHTCNGARCCNMGNAGYTCNTCNMGNTCNCCN TCNAAYTCNTCNYTNTCNGCNYTNAAYGAYYTNAGYACNGARAARACNACNTCNMGNCCN AGYTCNATHGTNTCNCCNCAYACNGARTTYGTNACNYTNACNGGNAAYATHGARCARYTN GCNCARAAYATHAGYTTYGARTAYGARGARGCNYTNGAYACNACNYTNGARAGYATHTCN ATGACNCARGARGAYACN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGAAYATHYTNGCNACNCAYCAYCCNCCN GAYAARGAYTAYGGNTTYATGAARGTNGAYGARCCNCCNACNCCNTAYAAYMGNGCNGAY AAYGARGAYAGYGARGGNGARYTNGCNACNGAYMGNAARAAYAGYATGGGNGARTGYTCN GGNGCNGTNGAYCCNGCNTCNYTNGCNTCNMGNYTNGARCAYAGYGCNGARGARGGNGCN AARAARCAYTTYTAYGGNATHGARGARGAYGAYAGYTCNGGNGAYGARAAYGARACNGAR GARGARMGNAARCAYMGNAARGCNTTYYTNYTNAARMGNAARATGCAYTAYAAYGARTAY CARGCNGTNCARYTNGCNAARAARYTNYTNGCNGARGARGARGARGARGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGNCARCAR MGNGARCAYMGNAARYTNGAYMGNAGYYTNAGYGAYGGNGARTGYGAYMGNYTN---CAY CCNAGYAGYTCNTCNCARAARACNGTNAAYTCNAGYMGNTAYAARACNGARYTNTGYMGN CCNTTYGARGARAGYGGNCARTGYAARTAYGGNGAYAARTGYCARTTYGCNCAYGGNATG CARGARYTNMGNAAYYTNGCNMGNCAYCCNAARTAYAARACNGARYTNTGYMGNACNTTY CAYACNATHGGNTTYTGYCCNTAYGGNCCNMGNTGYCAYTTYATHCAYAAYGARGARGAR MGNAAYACNAGYCCNCARGGNGCNAARTCNACNGCNATHAARGCNAGYAGY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GTNMGN MGNAARGGNGARGARGAYTAYACNAARTAYTGGYTNGCNMGNMGNCAYAGYAARAARGTN GCNMGNACNGCNAARGARAARTCNTGGACNCARTAYGGNGARAARYTNMGNGARACNTGY NNNNNNTCNCCNMGNGARTTYTAYAARAGYGTNAARMGNGTNMGNGAYGARCCNTAYGAY CCNACNACNNNNATHAAYGAYGCNNNNNNNNNNNNNYTNNNNNNNNNNGANGARNNNNNN NNNMGNTGGGARNNNTAYTTYAARAAYYTNYTNAAYCCNTCNGGNGTNYTNAAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNMGNMGNATHGGNAARTCNTCNGCNTCNTCNGAR MGNTAYGARAARAGYYTNGTNAARTTYTGYCAYTGYTAYTCNGGNGTNGAYGCNTGGGAR YTNGARMGNTAYGGNTAYAARCAYTGYAARYTNGCNACNAARYTNMGNYTNYTNAARAAY YTNATGGARGCNCARTTYGAYTAYAAYYTNAARTTYAARGARAARGTNAAYGARGCNAGY GCNGARGAYATGMGNYTNYTNCCNATHGGNMGNGAYAARAAYGGNCARGCNTAYTGGTAY TTYYTNGAYCARGAYTAYAAYYTNYTNYTNTAYCARGARGARGTNGAYGAYGARGCNGCN GAYACNTGGAARYTNGTNTGYMGNGAYMGNGARCARYTNGCNTGYYTNATHAAYTCNYTN CARTCNACNGTNAARGARGARGARGAYGAYAARAGYAGYGARTCNAGYAGYAARGARGGN TCNCCNGARAARGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARGARYTN AAYAARYTNCARTTYGARYTNGARTGGMGNGARTCNTCNTTYATGGAYAGYCARCARACN TGGGCNGARMGNTTYGAYMGNGTNTGYCARGARAAYTCNYTNYTNATGGCNACNYTNGAR GCNMGNACNGARGARYTNMGNMGNACNTCNGCNMGNAARATGGCNATHGCNMGNGARMGN GAYGARYTNYTNGCNYTNYTNGAYGTNAARGARMGNGCNMGNTAYGARATGACNMGNAGY AAYTCNGARGAYGARGARTAYGGNACNTTYTCNTCNACNGARYTNGCNGTNYTNGGNGCN TGYAARTGYMGNGAYGTNAAYCCNGARCCNTGYGGNTGYGCNTAYGCNGCNGCNAAYYTN MGNAARGARGTNTTYAARYTNAARGAYCARYTNGGNATGAGYCARAAYMGNTGYGAYGAR GCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARCARAARAARYTNYTNGAYYTNATHGAYCARCARCAYCARACNGARGAR GGNGARYTNACNTAYAARYTNGCNYTNGARCARAAYGARGARGCNGARAARYTNMGNAAR GARTTYGCNATHMGNAARMGNATGGGNATHAARGARATHCARCARYTNTAYATHGAYGAY GTNGTNAARGAYMGNMGNGCNYTNGCNCAYGCNAGYGARACNCARGARGAYGAYCAYAGY GARATGYTNAAYYTNYTNGCNTCNGTNCAYATHAAYYTNATHCARAARGCNAARAARAGY CAYCAYYTNACNTCNGAYCARATHGARGAYTTYATGGCNACNGCNMGNGAYGAYYTNATG GGNGTNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TCNTGYTTYGCN GAYGGNGTNATGGGNAARGAYGARYTNGCNAAYYTNTTYGCNGARATHGAYTCNCAYAAY ACNAAYAAYATHGAYACNGGNGARYTNTGYGAYTAYTTYTCNACNCAYYTNGGNGARTTY AARGARGTNTTYGCNACNYTNGARGAYYTNAAYACNAARATGACNAAYGTNYTNTTYGGN ATGTCNAARAGYTAYCARCARGCNAAYMGNACNGAYAARTTYGTNAARMGNTTYYTNYTN MGNGARATHYTNAAYCARATGTCNGCNYTNCARAGYCCNYTNGARGCNGCNTCNGAYACN YTNGAYYTNCARGCNAARGARGARGGNGARGGNATHACNCCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHCAR YTNACNYTNAARAARGAYTTYGTNACNAARATHGGNACNAGYCAYGAYACNACNMGNTAY TAYTTYATHYTNYTNATHMGNAAYGGNTAYCARATHATHTGYACNCARATGYTNTCNACN CAYGAYCCNATGGTNMGNGGNAGYYTNGAYTTYCCNAAYYTNATHAARYTNAAYGGNATH ACNGGNAGYTTYMGNGTNACNATHGAYATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TGYYTNGCNAARAGYAAYGCNATGTAYGTNGTNGCNAAY ATGGGNGAYMGNCARCCNTGYAAYCCNGCNCARGAYCCNAARTGYCCNGCNGAYGGNMGN TAYCARTTYAAYACNGAYGTNGTNTAYGGNCCNGAYGGNACNYTNGTNGCNMGNTAYCAY AARMGNCAYYTNTTYTAYGARTTYCAYTAYGAYACNCCNGARACNGARATGATHCAYTTY GAYACNCCNTTYGGNMGNTTYGGNYTNYTNGTNTGYTTYGAYYTNYTNTTYTAYGARCCN ACNGTNTCNYTNGTNGTNGAYCAYGAYGTNGCNAAYATHYTNTTYCCNACNGCNTGGATG GAYGCNYTNCCNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARTAYGAYGAY GAYGTNTGYMGNGAYTTYATGMGNAAYGTNTGYACNMGNGGNAGYMGNTGYMGNTAYMGN CAYCCNAGYGGNGARGARMGNCCNGARTCNGCNGCNMGNTCNGAYYTNACNTTYTGYCAY GAYTTYCARAAYAAYGGNTGYCAYMGNTCNAAYTGYAARTTYYTNCAYTGYACNMGNGAR GARGARGARTAYTTYCAYAARACNGGNYTNYTNCCNCCNMGNYTNAAY------------ ---CARACNTCNATGGGNATHMGNGCNGARATHCCNATHTGYMGNGAYTTYATGAARGGN GARTGYAARMGNGGNAGYAARTGYAARTAYMGNCAYGTNACNAGYGARTAYGARATG--- GAYAGYCCNCAYGGNGAYGGNGARGAYGTNATHGAYMGNGAYMGNTTYTAYGAYGGNCCN GGNGAYATGAARMGNMGNMGNYTNGAYGAYGCNTAYYTNCCNGTNGGNGAYGGNGTNAGY TAYGARYTNYTNGARGAYGARAAYATHATGYTNMGNMGNAARGTNGARGARYTNAARAAR CARGTNAAYGAYYTNACNGCNATH------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATHAGYGTNGCNTGYGAYGTNYTNAAYTCN--------- AARGAYGARGCNYTNACNGCNACNCARTCNGTNGAYGCNGAYGTNCCNCCNACNAGYCCN CCNAARYTNTCNGTNGAYGAYTCNGARAAYTAYAGYGCNTCNACNAAYATHTGGACNGTN MGNGARGAYAGYGAYGTNACNYTNACNTGYGARGTNAGYGGNGGNAARCCNGARGTNTCN GARGTNACNYTNMGNTGYCCNGGNGAYGGNAAYGCNACNACNCARGGNCCNTCNGCNTCN YTNTCNACNAARTTYACNYTNCARAAYAAYAAYAARGAY---TGYACNTGYTCNGCNGTN CAYGTNAGYGGNTGYTAYGAYAARCARGCNTCNYTNACNYTNAAYGTNCARTAYACNCCN TTYGTNCARTCNTTYACNACNAAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARATHATHGCNACNCCNTTYGGNGGNYTNAGYCCNMGNATHTTYTTYAAYTCNTAYAGY MGNGGNGTNYTNAGYTGYGTNTCNGGNCARGAYGAYTGYYTNYTNYTNACNGAYGCNMGN TGY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGNCARTTYGAYGCNMGNCARAARYTNGCNCCNAAR AARCCNGTNGAYGCNMGNAAYAARATHAAYGTNAAYAARCARAARGGNYTNGGNGAYGCN MGNAAYAARATHGTNGCNAARCARGTNAARAARGGNACNTTYGAYGCNMGNTCNYTNYTN AARAARAARGARCARCCNGTNAARMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNGGNAARTTYTTYTGYATHGAY AAYGTNCARGCNTGYTGYCCNAAYAAYACNTAYGGNAARGAYTGYACNCCNTGYCCNGGN GGNATHACNAARCCNTGYTTYGGNAAYGGNAARTGYGAYGGNGARGGNACNMGNGARGGN ACNGGNGTNTGYYTNTGYACNTCNGGNTAYMGNGGNGAYYTNTGYGAYGCNTGYAARGAY GGNTAYTAYGARGARACNAARAAYGAYTCNCAYATHGTNTGYAARGGNTTYCAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AARAARYTNAARAGYAARGTNGARYTNGCNGCNGTN YTNYTNAGYYTNGGNGAYACNGARGARGCNMGNAGYCAYYTNAAYTCNTGYYTNGARGGN YTNGCNTCNTGYGGNTCNTCNYTNGARATHAGYAAYGTNTAYAAYGARGTNGGNATHYTN YTNACNCARYTNGGNACNYTNGAYGARGCNAARAARTGYCAYCARACNGCNATHAARATG TGYAGYTCNCAYGGNGGNGAYAARMGNYTNGARGCNYTNGCNTAYCARAAYYTNGGNGCN GTNAARAAYTTYCARAARGAYTAYCARGAYTCNYTNGTNTTYCAYMGNAARGCNGARMGN ATHCAYAGYAARYTNGGNAAYMGNMGNAAYCARGGNCAYTGYTTYATHAAYYTNGGNTAY GCNYTNATGAARYTNGARMGNTTYCARGAYGCNCAYGAYGCNTTYYTNCAYGCNCAYCAR GCNGCNMGNGAYTGYAARGAYMGNAARGTN---TGGGARGTNYTNGARGCNYTNGGNGAY GTNACNGCNAARATGGAYAAYCAYGAYCARGCNATGGGNAAYTAYMGNGARGCNYTNMGN AGYTTYYTNGTNTCNCCNGAYTCNGARAAYGARACNGTNMGNAAYMGNYTNGAYGGNAAR TAYCAYAAYGCNGARAARGCNCCNTAYACNACNATGCCNACNAARATHYTNTTYGCNCAR GCNGTNGAYAARACNGAYACNMGNMGNGAYAAYACNGTNCCNGTNGTNGTNGARATGCCN AARGAYGCNATHAGYAARAAYGGNGTNATHGARGTNAARGGNGGNCCNMGNAARAARAAR ------------MGNTTYYTNAARGTNMGNMGNTCNGGNACNYTNMGNCARTTYGARAAR ATHGCNYTNGGNYTNGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GGNGARGTNGGNGGNMGNTTYTTYCAYTTYTGGCCNCCNMGNGAYGTNCARYTNYTNGCN TGGATHTCNCAYTGGATGMGNMGNGGNGCNATHCCNATHGTNACNATGAAYYTNCARAAR GGNYTNGAYCCNGARTGGACNGTNCCNGAYGCNTGGCAYCAYCARATGGTNTAYGGNGTN TGYTCNAARGGNATGTAYYTNACNAAYCCNYTNCARATHTAYGGNGARCCNYTNGCNATG CARMGNYTNTGYAGYGAYTCNGTNYTNYTNGTNAARMGNCARGAYATHTTYGTNMGNTTY MGNGARTTYACNGARYTNGGNCARYTNYTNAGYCAYCCNGAYACNMGNTGGMGNACNATG AAYGTNYTNGGNCARGTNGTNAAYGTNYTNMGNGARTTYAAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYCARGAYATHYTNYTNCARYTNGAR MGNGAYAAYGTNGTNGTNTTYACNCCNGCNMGNMGNGTNAARGGNMGNMGNGTNGTNTGY TAYGAYGAYMGNTAYGTNYTNAARYTNGCNAGYGARACNGAYGGNGTNGTNGTNTCNAAY GAYGTNTAYMGNGAYYTNGTNAAYGARGAYCCNGARTTYCARMGNGTNGTNGARCARMGN YTNYTNATGTAYAGYTTYGTNAAYGAYMGNTTYATGCCNCCNCARGAYCCNYTNGGNMGN GCNGGNCCNACNYTNGAYAAYTTY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATHCARAARCARYTNGGNYTNTCNGCNGGNTCNGARYTN CCNATHGGNCARAARCCNGTNACNAGYMGNGARAARTTYGTNMGNCARTTYYTNACNGAR MGNGARGARGARTTYACNTAYYTNCARAARYTNAARGTNTTYTGYGGNACNTGGAAYGTN AAYGGNCARTCNCCNATHGARGCNYTNGAYMGNTGGATGTGYGTNGAYAGYGARCCNCCN GAYATHTAYGCNATHGGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GAYMGNTTYGAYGTNMGNGCNAAYYTNGAYTTYATHCCNGARTAYACNTCNCCNAARGAY GCNATHMGNGTNTCNGARYTNGAYGAYGAYGARGARMGNAARGCNAAYTAYGARMGNTAY MGNACNYTNGTNGARAAYGARGCNGCNGGNYTNAGYGARGARCAYTGYYTNCAYCARATH TAYYTNGAYGARCAYTTYGGNACNATHAAYMGNGGNAAYGARGAYGARAARAARAARYTN GCNGAYAARAARGCNGCNATHGGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYAARACNAARTCNATGATGGARAAR ATHAARAGYGTNGARTAYAGYACNYTNAARGARYTNTCNATHTCNGGNGARAGYCARMGN MGNTGYYTNCARGARATGGCNMGNYTNYTNGAYTTYGCNTGGATHACNCARYTNCCNCCN ACNGAYCCNTCNGGNMGNTTYTAYGAYCCNAARYTNTCNGAYGARAAYGARGGNYTNMGN MGNGARYTNCARTCNYTNMGNACNCARTTYGAYACNYTNTCNTCNMGNGCNAARCARCAR GARGARMGNYTNACNGCNACNGTNGARYTNAARAARGAYTGGGARGAYTCNYTNTGYMGN CAY------ATGAARAAYAARMGNTCNYTNAGYTGGTCNGARTCNGGNGAYGAYTAYAAR GTNATGGARGARMGN---------------AGYYTNCAR------------CAR------ ------MGNGARYTNGAYAARGARMGNTCNCARCAYYTNAAYAAYTGYAARATGYTNGAY CCNGARYTNMGNGARCARCAYGARYTNATHAARAARAGYTAYGCNAAYGTNYTNTTYAGY TGGGGNYTNYTNAAYCARMGNGCNAAYATHYTNAARCAYACNGAYACNMGNCCNCCNCCN CAYAARGGNATHGAYTTYGTNACNMGNTGYTCNCAYTGYACNATGAARACNMGNAAYGCN AAYTGYGARCAYTGYAAYTAYCCNGCNYTNYTNTGYTCNATHTGYCAYATHGGNGTNAAR GGNAAYGCNAAYTTYTGYATHACNTGYGGNCAYGGNGGNCAYACNCARCAYYTNYTNGAY TGGTTYCARGARGARACNGCNTGYCCNGCNGCNTGYGGNTGYCARTGYCARTCNGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNATGGGNGCNAAYTCNGARATGGARTCNGTNTGYGGNCARYTNGAR TCNGARAARMGNCARYTNATGGARTGYYTNGARCARTTYAARCARAARYTNGARGARAAR GAYAGYCARATHGCNGCNYTNGARACNMGNYTNAGYCARMGNAAYGCNCARATHGTNCAR TTYCARGARGAYATHAGYGAYAARTGYAAYACNATHTCNAARYTNGARAARGARGTNTGG ACNCAYAARACNAARATHAAYAARYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNGCNTCNGARTAYAAYATHCCNTTYYTNYTNTAYMGN GARGGNCARGGNAARAARGTNAARGGNGARGTNTAYGTNGTNGAYGAYAARATGYTNAGY TAYATGGAYAAYTTYGARAGYCAYCCNGAYTTYTAYMGNMGNGARCARACNCARATHACN YTNGAYGARAGYTGYTGYAAYMGNGGNGAYTCNGARGGNGGNCARYTNYTNTGYTGGGTN TAYTTYYTNCCNMGNTTYAARCCNCAYATHYTNGARYTNCCNTTYATGGAYAAYTAYGAY ACNAGYAGYGCNAAYCAYCCNCCNTAYGTNGAYTGYCAYMGNAARCAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TGYAARACNGARACNMGNAAY ACNACNACNATHAARGTNGTNGTNATHTTYATHATHTGYGTNGTNTCNYTNYTNTTYGTN TAYATGATGTTYYTNYTNTGYYTNGAYCCNYTNATHCARMGNMGNCCNGCN---CAYTAY CARCARCAYACNAAYGARGARGTNAAYYTNGARGAYYTN---TCNGCNCAYMGNTCNGAR ---------GTNGARACNCCNACNAGYGCN------GARGTNCARGARTCNACNGCNMGN CARMGNTCNYTNYTNAAYATGGTNACN--------------------------------- ------------------------------------------TCNGCNAGYGCNGGNACN GCNAARGCNAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNGGNTTYGARMGNTCNMGNYTNGCNYTN AAYACNATHYTNCARCCNTTYAAYTCNYTNGGNGTNCCNATHYTNCAYGTNATHGGNAAY CAYGARYTNTAYAAYTTYAAYMGNACNTTYTAYGTNMGNTCNGAR--------------- ------------YTNAAYTGYGGNGCNTCNAGYCARAAYCCNGAYGTNYTNTAYTAYACN MGNGTNCCNCAYCCNAARYTNMGNATHGTNACNYTNGAYTCNTAYGAYATHAGYYTNYTN GGNTAYGARGAYCARCARGARCAYGARAAYTAYAARYTNGCNGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CARYTNAARAARMGNGTNGAYGCNAAYGAR GARGGNATHACNAARYTNATGTCNYTNATGGARGAYTGGATGMGNGARGTNCARGCNYTN AARGAYGCNCARAARMGNYTNGARGAYAARGTNAAYAGYGTNAAYYTNGAYGAYGTNAAY AARMGNATHGAYGAYYTNAAYGCNYTNATHAAR---------------------GAYYTN AAYGARAARATGYTNGCNYTNCCNACNATGGARGARYTNGAR------------CARTTY GTNACNTGGCCNCARYTNGARGAYGCNYTNAARGGNGTNMGNMGNGAYATGGARGCNATG CARCCNATHACNGARGARMGNGTNGTNATHGARATGGCNGCNCARACNGARCCNCCNAGY MGNCCNGCNTCNGCNMGNCCNATHTCNMGNGCNTCNTCNGCNMGNACNGCNGGNCCNTCN TCNGARYTNYTNGAYATHYTNGARMGNYTNGGNCARYTNTCNGARGCNCAYGARGCNYTN ACNAARMGNGTNGARGARYTNGARAARYTNYTNGCNCARAARGCNGAYAARAGYGAYYTN GARGGNYTNGGNGTNCCNGAYGAYYTNYTNGARACNYTNMGNAARYTNCARGARGAYYTN YTNGCNYTNCARGARGGNCARYTNAARGAYGARGGNGTNYTNAARMGNYTNCARGARGCN ATHGARAARYTNAARACNGAYATGGARAARYTNAAYGGNTCNYTNCARGARGTNGTNGAR GAYGTNGCNCARMGNGCNAARGARATHCARGAYYTNGCNMGNTAYTGYGAYGARYTNAAY GARAARAARGCNGAYAARGARTAYGTNGCNATGGARGTNGAYGTNAARGCNGAYMGNAAR CARYTNGAYGGNAARGTNAAYCAYAGYYTNTTYGAYGCNGCNACNAGYGARYTNAAYMGN ATHATHAARGARATHYTNGARAARYTNAAYGGNCAYGARGARGGNTGGMGNTCNGCNYTN GCNAARGCNATGGARGARYTNGAYGGNAARYTNGAYMGNATGGARYTNAGYGCNYTNAAR GAYTGGYTNGARAARCARYTNAARGCNYTNAAYAAYAARATHAARCARGCNTCNGCNAAY TGGGAYYTNGAYGAYGARGCNGCNGGNATGMGNAARCARYTNATHCARMGNTTYAAYTGY YTNTCNTGYGAYAARAARYTNGAYGTNATGCCNCARCCNCCNATHGCNTCNATHCCNYTN AAYTAYGGNATGCCNAARTCNMGNTCNCCNMGNCCNTAYACNACNTTYGARYTNGAYCAR ATHMGNCARCAYGCNMGNAGYYTNGGNYTNAGYCARGARCCNATGGAYTAYTAYGCNACN ATHMGNCARTGYGGNGGNAGYCAYACNYTNACNTAYCCNAAYAARMGNACNACNMGNYTN AAYAAYYTNGGNCARYTNTTYAARGARGARGARACNGTNTAYCCNYTNTAYAARGARGAR GTNGAYGTNCARGGNATGGAYGGNCAYATHTAYAARGGNMGNATGGAYAAYAAYMGNYTN GARGCNAARYTNCCNGTNCCNYTNATGGARCARCARGTNCCNATGCCN------------ ------------------------------MGNCCNATGTCNGCNMGNAAYCCNMGNCCN CCNTCNGCNMGNCCNACNTCNTCNAARACNGCNGTNCAYGTNMGNACNAGYCCNCCNCCN GAYGTNACN---------CCNCCNCCNGAYAAYAGYMGNGCNGGNGGNTCNMGNACNACN ACNCCNCARCCNGARGAYACNGARGCNGCNGTNGARGCNGTNCARGARGARAAYCCNCCN CCNGARCCNCARGAYCARGARGTNGARCARCCNCARGARCARGARGTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNYTNMGNYTNGCNMGNCAY CARTCNACNMGNGCNGGNCARGGNGGNTTYGGNTAYYTNMGNGARTGGYTNTGGTGGGCN GGNATGATHYTNATGATHGTNGGNGARYTNGCNAAYTTYGCNGCNTAYGCNTTYGCNCCN GCNACNYTNGTNACNCCNYTNGGNGCNYTNAGYGTNATHGTNAGYGCNGTNYTNTCNTCN MGNGTNYTNAARGARAAYYTNAAYYTNYTNGGNAARATHGGNTGYTTYYTNTGYGTNYTN GGNTCNACNGTNATGGTNATHCAYTCNCCNAARGARCARGARGTNGARGAYGTNGARCAR YTNTTYATHAARGCNAARGAYCCNGCNTTYYTNGTNTAYTCNGTNGTNGTNGTNGCNATH GCNGTNACNYTNATHGTNTAYCAYGCNCCNMGNTAYGGNAGYAARAAYGTNYTNATHTAY ATH--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNGGNTTYGCNATGTTYYTNYTNTGYAARTAYATHGCNMGNYTNGARTGGGGN CARMGNTCNYTNMGNTCNGARMGNGCNATHGARMGNGTNAARCARTCNTAYGTNCCNCAY GARYTNTGYGARACNACNATGGCNMGNMGNATHAARGAYGTNMGNTAYGGNAARGARAGY GAYGTNTAYCARCARTAYGTNGCNAGYATHCCNMGNGARGARMGNTCNGTNGAY------ ---GAYCCNCARACNCCNAAYAARGAYGTNTTYATGAGYMGNMGNACNTGGGAYCAYAGY GTNMGNCARTGGMGNAARGAYYTNTAYGCNTGGGCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARAARAARAARAARAARAARAARAAR CAYAARCAYCAYAGYAARAARGARGARGARGARGARGGNAAYGARGGNGAR--------- ---------------GARAARGARAAYAARCAYMGNAARAGYMGNAARMGNAARCAYAGY AGYAARGARGTNAAYGGNGARGTNGGNGARAARGARGGNGGNAARCARATGGGNGARGCN ACNGAR---AAYAAYGCNGARCCNAARAAR------------TCNGCNMGNAARCAYTCN CAYMGNMGNMGNMGNAARCAYMGNMGNMGNACNYTNTCNAARTCNGARAARTCNAAR--- ------------------TCNCAYAAYAAYACNGARACNGARAARGTNAAYGCNAARGAR CCNAARGTNAARATHGAYTAYAAYGAYGARGARGARGCNGAYGCNTCNTCNGARGARAAY YTNGAR---ACNGGNGARCCNAARATHAARMGNTTYMGNCAYTCNCAYAARAARCAYMGN AARAGYGAYACNMGNGTNGAYGARATH---GAYGGNAAYAARGCNGARGAYGGNAARACN GAYGCNGARATHGGNATHACNTAYAARACNCAYAARAARYTNGCNGARGTNGAYAARGTN ATHGGNGAYGCNYTNAARGTNATGAAYAARAAYTCNCARATGAARGAYYTNAARYTNGTN AGYAGYAARGARGCNGCNGAYAAYCCNCAYAGYAARACNCCNGGNAGYGCNACNMGNAAR MGNGGNGCNAGYTGYTCNAGYACNGARGCNGTNACNCCNGGNAARGTNGCNAARGTNGAY AARGCNGARGTNGTNGARGAYACNTGGAGYAARATGGARGGNYTNTAYGARAAYMGNGTN GARGARGARAAYAARAGYAARTGGGAYACNGAYTCNGARGARGCNGAYGAYGCNATHAAR GCNACNATHMGNCCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARACNATHTTYGGNACNCCNTGG CARTTYGGNGGNACNTTYAAYAGYMGNGGNGGNGTNATGCARCAYAARGAYTCNGAYGTN GTNYTNGTNGTNCCNGCNGGNGCNGTNGAYACNGGNCAYTAYGTNGAYATHTAYGGNGCN GTNTTYACNGAYCCNGTNCARATHMGNCARAARTTYAARATHAGYCCNGARGARATGYTN ATHACNCCNGCNGTNGARTAYTAYACNAAYGTNAAYGAYACNTTYMGNAARCAYYTNACN ATHCAYYTNCCNCARGCNGTNCCN---MGNATGGAYTCNAGYTTYGTNAARGTNTAYTGY TTYACNATGTCNGARCAYGGNGARGTNATGGTNCARCARATHCCNTCNMGNTCNAARTCN AAYGCNYTNCCNGAYAGYTTYTAYGARCAYGGNGGNGARACNAAYAGYATHMGNGTNAAY ACNTGYCAYTTYAGYGGNTAYTTYTGYACNTAYTGYAARAAR---GARGAYATGCCNTCN GTNTGYACNATGGTNTTYGGNTCNCAYGTNCARATHTCNCCNACNMGNMGNGARGTNMGN GTNATGGTNYTNATHTGGGAYCAYMGNYTNAARATHACNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GTNMGNGGNYTNTGGTCNYTNYTNGGNAGY TCNGGNACNTCNGTNAAYYTNGCNGAYTGYAGYGGNGTNACNYTNGCNGTNGAYYTNAGY GCNTGGATHYTNCARTGYTCNYTNCCNCCNMGNTAYTTYGGNYTNMGNAAYGTNTTYTAY MGNGCNAARMGNYTNYTNTCNATGGGNYTNAARYTNGTNTTYGTNTCNGAYAGYCARAAR CCNCCNGARYTNAARAARMGNATHMGNGGNGARACNTAYAAYCARGTNGTNMGNGARTAY ATHCARATGYTNCARGCNYTNGGNYTNACNGTNYTNGARAGYCCNGGNGARGCNGARAAR YTNTGYGCNGCNYTNAAYGARGCNGGNGTNGTNGAYGGNTGYYTNACNAAYGAYGGNGAY GTNTTYYTNTAYGGNGCNMGNAAYGTNTAYMGNAAYTGGACNACNGARGGNAARGAY--- ---------ACNYTNGTNACNYTNGTNTCNYTNACNGARGARCARAAYATHTCNMGNMGN GAYYTNGTNACNTTYGCNYTNYTNAGYGGNTGYGAYATGTGYCCNGGNGTNCCNGGNATH GGNCARMGNAARTTYGTNGARYTNYTNCARGARTTYAARAGYAAYGGNGTNACNGAYTCN YTNGARMGNGTNAARAGYTGGGCNAGYAGYCCNGARYTNAARGAYYTNGCNGAYYTNCAR TGYAGYYTNYTNAGYYTNAARAARGGNAARCAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AGYMGNTCNGCNATHGAYACNGCNTGYAAYYTNYTNCAR AAYATHGCNYTNGCNGCNGCNGGNGTNATHGTNCCNTCNATHTTYGGNGCNGTNTAYTTY GTNYTNTTYYTNGTNGTNYTNACNYTNTGGGGNTGYTAYMGNAAYATHGGNGCNTCNYTN GGNTAYYTNMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYATHGTNATHGGNTAYAAYAGYTCNGAYTTYGAR TTYGTNAARAARGTNGCNGCNACNTTYMGNAARGARGGNYTNTCNGTNTGGTAYCCNGAR CCNGAYAGY---GGNTCNCARAARAGYCARTAYYTNYTNGCNTGYAARGTNTTYGTNGTN ATHATGAGYGARAAYGGNGCNGARGAYAARCARYTNCAYGARCARYTNTCNYTNGCNTAY ATHTCNAAYTCNGCNATHTAYCCNYTNAGYYTNTGYMGNTTYMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ACNGCNTAYAAYGTNGAYATHAARACNGCNGTNGTNCAY CARGGNGARGCNGGNAGYATGTTYGGNTAYGCNGTNGCNCARCAYATHGAYCARTCNACN AAYTGGYTNYTNATHGGNGCNCCNMGNGCNCARACNTCNCARCCNGGNGTNTCNMGNGGN GGNGCNGTNYTNMGNTGYAARACNGAYMGNMGNAAYTCNTGYCARGARGTNCCNTTYGAY TCNMGNGGNAAYAAYATHMGNTTY------AAYGGNTCNGCNTAYYTNCCNATHGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARTCNACNGAYGARAARTGGAARGAYATHGARAAYTTYATHAAY------GGN TCNCCNCCNACNAARAARMGNAARMGNTGYGAYTCNGGNGGNTCNGGNCAYACNTCNGAY GAY---GAYGARGAYGAYGAYGAYGAYATGTCNTAYAARGAYGAYGAYAGY---GAYGAY GAYATGTCNGAYATHGAYTCNGAYYTNGGNCARATGTCNCCNCARGARTGYGARTCNYTN GTNGCNGCNGGNAARAARCARAARCARTTYTTYTGGCARTAYAAYGTNCARTCNAARGGN CCNAARGGNACNMGNYTNAARYTNTCNGTNGARACNCCNGAYGAYCCNCAYGTNYTNAAY TCNTTYGARGAYCCNGTNTTYGAYGCNGGNAAYACNGCNATHGCNGGNATHMGNCAYGGN GGNAARGCNMGNAARGGNGAYGGNAAYGARGTNACNCCNAAYCCNAARAARYTNTAYATG ATHGGNCARCARYTNYTNMGNYTNAAYMGNCARATHAAYAGYTAYCARYTNAGYGCNGAY ATHCCNGCNAGYCARMGNAAYAARTCNMGNAARGARAARAAYAARYTNGCNTCNMGNGCN TGYMGNYTNAARAARAARGCNCARCAYGARGCNAAYAARATHAARYTNAAYGGNYTNGAR CARGARCAYTCNCARYTNAAYMGNGTNYTNGGNYTNATGTGGCCNGAYYTNAARCARGAR GTNAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARACNATHTCNYTNGGNTCNYTNTCN CARGARGARMGNYTNAARAARMGNGCNGARAARTTYGGNGTNGTNTCNGARGARGCNAAR AARCARYTNMGNGCNGARMGNTTYGGNATHAAYTCNTCNGAYACNACNGGNGGNAARYTN TCNACNGTNACNGGNACNGCNAAYATGGCNGTNYTNAARAARMGNGCNGARMGNTTYGGN ACNGTNACNTCNACNTCNYTNTCNAARGCNGAYCARGARGARMGNAARMGNAARMGNYTN GARMGNTTYGGNGCNTCNACNACNACNAGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GCNACNAARGTNAARCAYGGNATHGTNTTYATGGAYAAYYTNTGYGCN GARATHYTNCAYTGGAAYGGNGGNATGGGNTTYYTNYTNGAYGCNGGNGCNGTNGAYGTN MGNGARTTYTCNTCNTTYGARAGYGCNGAYGAYTCNCAYAARAARGGNGTNTTYYTNGTN GGNGCNCCNYTNGTNGGNGTNACNGCNMGNGTNATHCARGAYGTNGTNTCNCARAGYTCN TTYCARTAYGTNGTNGTNATHACNACNGCNAGYAARTCNATHAAYGCNCARTCNCARGCN TCNGAYGTNGAYCCNTCNGTNATHTTYGARACNTTYGARGAYAGYGTNYTNGARTGGATG GGNAAYATGAAYTAYACNGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TTYGCNGTNCCNGGNYTNTGGGCNGARGARGAYATHGAR ATGATHGTNGGNCAYTAYGGNATHGTNGTNATHGCNMGNAGYGGNTCNGAYCCNCARAAR TTYATHTAYGARTCNGAYGTNYTNAGYCARCAYMGNGARAAYATHYTNATHGTNACNGAR TGGATGAGYCARGAYATHAGYGCNACNAARGTNMGNMGNGCNYTNMGNMGNGGNGARAGY ATHAARTAYGTNGTNCARGAYGCNGTNATHGAYTAYATHMGNGARCAYMGNYTNTAYGGN TCNCCNGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AGYGCNGCNCARATHYTNCAYCCNTCNGGNCARGTNATGGTNTCNYTNTGY MGNGGNCARGGNGGNACNCCNGCNGAYCARCCNGTNMGNTCNTGGCAYGAYAGYTGGCAR GTNGTNTCNATGGCNGCNAAYGCNGGNYTNGTNYTNGTNAAYGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARGCNGTNGCNTGYATG CARGCNCCNGGNACNGAYATGGARAARMGNYTNAARAARYTNCCNGARACNGGNYTNGGN CAYTCNYTNGTNGARTCNGCNTCNYTNYTNGGNCARGAYACNYTNYTNGGNTCNGTNTGY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNGAR GTNTAYGAYAAYGGNTAYTAYYTNGTNTGYGTNTGGTGYTTYATGACNTGGAARTGGGGN TTYTTYYTNTTYTAYTTYTCNMGNTCNTAYYTNMGNYTNTAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ACNTTYACNGTNAGYATHACNTAY AARACNTCNCCNCARTGYACNGCNYTNCARTGGYTNACNCCNCARCARACNGCNGGNAAR MGNCARCCNTAYYTNTTYAGYCARTGYGARGCNATHCAYGCNMGNAGYYTNTTYCCNTGY CARGAYACNCCNGCNGTNAARTTYCCNTAYACNGCNAAYGTNAARGCNCCNMGNGAYATH ACNGTNYTNATGAGYGCNMGNMGNGARGGNACNGARCCNGTNGAYGGNGAYAGYAGYCAR ATGGGNACN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNCCNAAR GCNCARYTNGARAAYGARAARMGNYTNMGNMGNGARATHGCNAAYAGYAAYGARMGNMGN MGNATGCARTGYATHAAYGCNGGNTTYAAYGCNYTNAARGGNYTNGTNCAYAAYACNGAR GGNGAYAARYTNAGYAARGCNGCNATHYTNCARCARACNGTNGAYCAYATHCARMGNYTN CARGARGARATHAGYAARYTNMGNGCNCAYGTNGARCAYYTNAARCAYGCNATHYTNGAR ATH------CARCAYGCNCARGGNATGGAYTCNMGNATHGARGAYACNMGNCCNCCNTCN AARMGNAARAARMGNGAYACNGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR GAYATHYTNGAYGCNYTNGAYMGNTTYGCNAARAARCCNTCN---GARGARATHCCNCCN GTNYTNGARGARTTYYTNGARAARGTNGCNAARAAYGGNGARACNYTNTTYCCNTGGGGN AARYTNCARCCNYTNGTNGTNAGYAARYTNGARCARGTNYTNMGNMGNYTNMGNGARGAR YTNTGYTCNGARAAYATHCARCCNTGYCCNAAYGTNGARAAYGTNMGNTTYGARGAYATG MGNMGNMGNATHATGGAYGCNGTNCAYAARTTYCAYGGNGCNCCNTTYACNATHCARMGN YTNTGYGARYTNYTNACNGARCCNAARMGNCAYTAYAARMGNAGYGAYAARTAYYTNMGN GGNATHGARAARAAYGTNYTNGTNGTNAGYACNGTNGAYCCNTTYGGNMGNAARATHGTN TCNGARTCNCARGCNAARCAYATGGTNAAYGGN---ATG---GAYACNAAYGGNGCNCAY CCNCCNTTYGTNGARACNAAYACNTCN---CCNYTNCCNCCNGTNCCNGAYTGG---GCN GGNACNGTNACNATGGCNACNTGYAAYACNAGYGGNCCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TAY ATHGGNGARTTYTAYYTNGAYCAYGAYTAYGGNCCNGAYMGNACNGGNGGNGARGGNCAR AARTGYMGNTTYGTNATHGGNACNMGNCARAAYGTNGAYMGNTAYYTNCARCARTTYMGN GAYYTNTTYACNGARGARGGNMGNMGNCARGTNAARATHGCNGTNCARAARCCNAAYCAR CCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AGYTCNAGYATH YTNYTNGCNTCNTCNAGYAARYTNGCNACNCCNACNAARACNAGYMGNGGNAGYACNCCN GARAARMGNTCNTCNGARMGNGARMGNTCNTCNGAYMGNGARAARACNCCNGAYAARGCN GGNTCNTCNMGNAGYAARTCNCARACNCCNGARAARGCNGGNCCNTCNGGNMGNCARGGN TCNAGY------------------------GARCCNCCNGARAARMGNAARMGN---ATH GARYTNACNGARGARGARATHCARCARCAYYTNAARAARAARGARAARCARGARGARGAR MGNATGAARATGCARGTNYTNGTNTCNAAYTTYTCNGARGARCARYTNAAYMGNTAYGAR ATG--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN GAYACNGTNATGGARYTNGGNYTNGTNAAYCCNAGYYTNGTNMGNCARCARACNTGGACN GTNGTNCARCAYCCNTCNAARMGNGAYCCNAARGTNMGNYTNTGGGGNCARYTNMGNGAY YTNGAYGCNTGYCAYGCNTTYACNCAYCARTGGCCNGTNTCNGCNTGYAAYAARCARYTN TTYACNACNYTNAAYATHGAYACNCARAAYATHYTNTTYAGYCARAARAARCARGTNGTN CCNATHTAYGCNTCNGGNYTNAGYATHYTNGARCCNATHMGNGGNGGNGTNGARTCNAAR AARGAYAGYAAYGCNCCNCCN------GCNGCNYTNGTNGAYACNAGYAARCARGARCCN CARGAYAGYMGNGTNGCNCARGAYTTYCCNCCNGTNAAYTTYGAYTGGAGYGTNAGYGGN YTNACNAAYCCNYTNGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ACNGGNGGNTGYGTNATHGAYGAYGCNYTNAARGARGTNYTNGARTAYGCNGTNMGN GAYTAYATHAARACNTGGTAYMGNCARYTNAGYGAYCAYGAYGGNTTYYTNGTNGAYGTN TGGCARTGYGCNCARAARGTNATHATHACNTTYGCNAGYMGNTCNAARGARATHGAYTGG ATGCCNTAYTTYACNCARMGNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CAYGGN---------CAYGAYAARCCNYTNGARTTYMGNTCNGAR ATHCAYAAYGCNGAYCAYATHYTNGARCAYYTNCARCARGTNATHGCNACNAARCCNAAR GAYCARYTNTCNGARGARGARYTNGARTTYCAYTAYTTYAARATGCAYGAYTAYGAYAAY AAYAAYAARYTNGAYGGNGTNGARATHGGNAARGCNYTNACNCAYTTYCAYGAYGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TTYGGNTCNYTN TCNGTNAGYGGNATHACNYTNAAYGCNGARTTYGAYAARAARTCNATHGAYATHGARCCN GGNTCNATHATHCAYCCNAAYYTNTAYTGYGAYCCNGARGARAARATGGAYMGNTGGATH GARMGNYTNACNCARYTNMGNAARAARAARYTNGARGGNGARGTNYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNGAYGARGAY TCNAARMGNGARGAYMGNGTNGCNAARGCNGGNYTNGARGCNATHATGMGNGARTAYGCN TTYGARYTNGCNAARGARCCNGTNAGYAARACNGAY---AARGGNCARGAYAARGAYAAR ATGYTNCCNAARAARAGYGAYAAYATGATGGCNCAYAGYAARGAYACNGGNTTYGAYGAY YTNGAYATGGARGAYGARAARAARGAYYTNATHAGYMGNGARATHAAYAARTTYMGNGAY MGNCAYAARGAYGARGAYGAYGAYAARGAYAARGAY---MGNGAY------------ATG GCNAARGARMGNGARMGNMGNYTNGARGARAARMGNMGNAARGARMGNYTNGARMGNATG ------CARMGNGARMGNGARATHYTN------------------MGNGARMGNCARGCN CCNGCNMGNTCNMGNTCNAARTCNMGNTCNGARTCNCCN---CCNMGNMGNAARMGNGAR AARTCNMGNTCN------------MGNGARAARAGYAGYMGNGAYMGNTCNMGNGARMGN MGNAARGARMGNGARATHGARGARGARGARGARGCNTAYGARMGNMGNAARYTNGARAAR AARYTNMGNGARAARGARGCNGCNTAYCARGARMGNYTNAARAAYTGGGARGCNMGNGAR MGNAARAARTCNMGNGARTAYGARAARGARAAYGARMGNGARGAYGARMGNAARGCNGAR GARGTNMGNGARGCNMGNMGNYTNAARGARTTYYTNGARGAYTAYGAYGAYYTNMGNGAY GAYCCNAARTTYTAYAARGGNAGYGCNYTNATGMGNMGNYTNAARGARMGNGARAARGAR AARGARGCNGAYAAYMGNGAYMGNCARMGNGARAARGARGARTTYGARGARATHAARMGN AARYTNTTYGAYCARGGNCAYCCNGAYGCNGARACNGARGTNGCNMGNATGGARMGNGAR MGNGARGARCAYYTNMGNCCNMGNYTNCARYTNYTNCARGARAARAARCCNTCN------ ---------------AAYGAYTCNGAYTCNGAYGGNGARATHCAYGAR------GARCCN TCNAARGCNGCNTCNMGNAGYCCN---GCNYTNGTNATGGCNGCNGCNGCNGCNGCNGCN CCNCCNCCNGCNCCNCARYTNCARCCNATHGCNTCNGTNGCNGCNAARCCNGAYMGNGAR CCNMGNGARTCNYTNTCNACNTCNCCNGTNTCNGARGAYTCNMGNATH---AGYGCNCCN CCNYTNTTYYTNGAYGARACNTCNCARTCNTCNYTNACNGCNCCNGCNCCNCAYACNGTN AARGARGARYTN---AARCCNAGYGCNYTNAGYMGNATH--------------------- GGNGCNAGYATHAGYCCNGCNGAYACNATGTCNCARTCNGCNATGACNGCNATGTCNCCN TCNGGNAGYGGNAARMGNMGNAARYTNACNGTNGGNGAYGTNTTYAAYCARGAYGAYGAY GAYAAYGGNGARCCNAARAARMGNAARYTNATHCCNYTNGAYTAYGGNGARGAYAGYAAY AGYAGYACNGARAARAARCCNGTNACNGCNGARGARAARMGNCARMGNATHAARCARYTN ATHGARAAYATHCCNACNGCNAARGAYGARYTNTTYGCNTAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYTGGGARGTNGCNGGN GGNGARGAYGAYTTYGARATHTTYYTNGCNAGYGTNAARGCNMGNTCNCARGCNACNMGN GCNCARGTNMGNAAYGGNTCNGGNGAYGGNCARAGYTCNACNAGYAGYAAYGCNATHACN AARGGNAGYTCNGTNGARATGGARTGGGAYCAYGARGCNGGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CCNAGY CAYATGMGNTGGATGYTNGGNCARCARGARGGNGAYAARGAYMGNMGNYTNMGNGCNTTY YTNACNATHATGAAYAGYGAYACNAGYYTNATGYTNAAYACNAAYTAYGTNCCNCARCAY YTNYTNATHATGTGYTGYGTNYTNMGNTAYYTNGTNACNTAYGGNMGNATHYTNCARMGN CARGARYTNGAYGCNTTYYTNGCNATGTCNGTNTCNCCNYTNYTNCAYGAYGTNCARACN ATGCARGAYYTNAARYTNCCNACNATHATGCCNMGNGGNAGYCARYTNGCNTCNYTNTTY ATGGCNGGNATHGARACNGCNGTNATGGCNAAYGAYGCNTGYGGNGCNCCNATHCCNTGG ACNATGACNTGYCCNTGGYTNTAYATGGAYGGNAARYTNTTYCAYTTYAARYTNYTNAAR GCNAAYAAYAAYACNCCNYTNATHGAYATHTGYGAYGGNCARGTNGARCARGTNATGMGN GTNGARMGNATGMGNCARGCNATHYTNGARAAYATHCAYGTNGARTTYGCNAARCCNYTN YTNCCNGGNTTYTAYAAYTAYGGNCCNTAYGGNCCNTAYCARGGNGGNCCNATGCCNTAY ATGCCNCCNGGNGCNCCNMGNGGNMGNGGNGGNCCNCCNCCNGCNGCNYTNGGNMGNGGN GGNMGNTCNCCNGTNGARACNMGNGGNGGNCARYTNGARATHGCNGGNGTNATGGTNAGY MGNTGGGGNGCNAAYATHGGN---MGNAGYGGNMGNGGNGGNAAYYTNCCNCCNCARGTN ATGTCNGTNGGNCARMGNGGNATGTAYCARGGNMGNGGNTTYGTNGCNACNMGNCCNATH AGYMGNGGNTAYTAYGCNMGNGGNMGNGGNATGCCNMGNCCNGTNMGNGTNGTNGCNAAR GTNAGY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AGYMGNAAYAARTCNTCNAGYATHCAR ACNYTNGAYCCNMGNAAYCARGCNGAYATHTCNCCNGTNCCN---------------TCN GARGARGARGCNMGNGTNAARGGNYTNYTNGAYGAYCCNCARATGATGGARGTNYTNATG GAYAARAARATHGTNAAYYTNATHCARYTNATGAARACNGAYCCNGARGARGCNCARAAY GTNGTNGTNCARGCNGAYGAYGAYYTNAARGCNAARATHAAYAARYTNATHTCNCAYGGN YTNYTNCARTTY---ATGTCNCARAAYMGNGCNAARCCNACNAAYGTNCCNTCNYTNYTN YTNGARGAYTCNGARAAYGARACNYTNTTYAAYATHYTNGGNMGNYTNTGYGTNACNATG GCNACNGGNGTNGTNCARYTNTAYYTNGCNGAYCCNCCNGAYMGNACNMGNTGGACNAAR MGNTGYTGYGGNGTNGCNTGYTTYATHAARGAYAGYTCNAARMGNGGNTTYTTYATHMGN GTNTAYGAYATHAARAARCARCARATGATHTGGGARCARGARYTNTAYACNCARTTYGTN TAYAARACNCCNMGNGAYTAYTTYCAYACNTTYGARGCNCAYAGYTGYCARGCNGGNYTN AAYTTYTCNAGYGARGAYGARGCNACNAAYTTYAARMGNGCNGTNGAYGGNAARYTNAAY GARMGNAARCARAARMGNCARGAYMGNMGNMGNCARACNGTNGCNCAYAARCAR------ ------------AAYCARMGNACNGTNGCNCCNCCNCCNCARMGNATG---GGNGGNTCN ACNCCNYTNGCNTCNCARCCNGTNACNGTNAAYGTNGAYCCNMGNACNAAYAGYAGYAGY TCNYTNAARAARGAR------------AARAARGGNAARGARAARAARAARYTNACNAAR GCNGAYATHGGNACNCCNTCNAAYTTYMGNCAYGTNAGYCAYGTNGGNTGGGAYCCNGAR AARGGNTTYGAYATGAAYAAYYTNGARCCNGAYATGCARAARYTNTTYCARTCNGTNGGN ATHACNCCNGAYGAYAAYGTNGAYAARGARACNYTNGAYTTYATHTAYGAYTTYGTNGAR AARCAYGGNGGNATHGARGCNGTNAARAARGARYTN------AAYMGNGGNCCNGCNCCN CCNCCNCCNATHGGNCCNAGYAGYCARGCN------------CCNCCNCCNCCNCCNAGY MGNGGNGGNGCNCCNCCNCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNGAYYTNACNGAYATGMGNAARCCNTAYAARGGNGAR MGNGAYATHTTYGAYGARTCNGAYYTNCCNTCNAARGAYCCNTTYAGYYTNTTYGARCAY TGGTTYCARGARGCNMGNAAYACNCCNACNATHYTNGARCCNAAYGCNATGGCNYTNGCN ACNGCNTCNAARGTNGGNCARCCNTCNGTNMGNATGGTNYTNATGAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNGGNGGNACNGCNGCNGGNCCNGCNAAYCARYTNTCN GARCCNTAYAARTCNTTYATGGAYGAYGCNGTNGARGGNGTNGCNATHGTNTCNYTNGGN AGYCAYGTNGTNGGNYTNCCNMGNCAYATHGARYTNAARATGATGAAYGCNTTYATGMGN YTNMGNGTNAARATHGTNTTYMGNATHAAYGTNACNTCNCCNAAYTCNTCNMGNATHYTN ACNTCNACNTGGATHCCNCARAAYGAYYTNYTNGGNCAYCAYAAYACNAARGTNTTYGTN AGYCAYTGYGGNAARAAYGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CCNTCNYTNTTYMGNCCNGTN GTNTTYACNGTNGCNACNTGYACNYTNAGYTTYGGNGGNGCNATGYTNTGGAAYTAYGAR ACNATHMGNAGYMGNTAYCARAAYATGATGTCNMGNGCNGAYMGNCARGGNGAYGAYGGN ------GCNCAYTCNAARATGTTYGGNTTYMGNGAYCAYGTNAAYAGYYTNTGGAARMGN YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYATGCAYGGNGGNGTNCCNATGGGN CARCCNAAYAGYMGNTGYGAYGAYGGNAARTCNCAYATHCARATHGAYTGGGAYCCNMGN TCNACNAARGARTTYACNTGY------GAYGTNAARCCNGARGTNCCNAARATHAARCAR ---------GTNTAYCAYCARTGYGAYAARGARGCNAARMGNCCNATHCAYATHTGYTAY CCNACNGCNATHGARTAY---GAYGARYTNCCNACNAGYGGNMGNCAYMGNCCNYTNTGG CCNAARTAYGGNGARTAYTCNTAYGTNCCNCCNCARMGNTGGYTNCAYAGYYTNGARCAY GGNGCNGCNGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TCNTCN AAYYTNGGNAAYCAYCCNAGYCAYTCNTCNGARACNYTNACNCAYYTNMGNAGYMGNTCN GTNTCNCCNGGNGTNGARAGYMGNCCNMGNTGYTCNAGYYTNGAYACNYTNGCNYTNYTN ACNGGNAAR---YTNCCNGAYTCNGGNATHAGYCAYATH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CARGTNTGYAARYTNGARGGNGAYGCNAARTTYCCNTTYGCNGGNMGNGAR GGNCARGTNTCNTGYTGYATHTCNAAYACNGTNTAYGTNTTYGGNGGNGTNATHCARGGN CARGGNAAYGARCCNCAYGARACNAAYGARYTNTTYACNTTYGAYTTYGGNTCNCARAAR TGGAGYMGNATHGAYACNYTNGGNTCNGCNCCNTCNGCNMGNTCNGCNGCNTCNYTNGTN GGNATHGGNACNAARYTNTTYYTNTTYGGNGGNYTNAGYCAYATHTGYGGNTGGTTYGAY GAYYTNCAYGTNTTYGAYACN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ACNGGNAGYCCNAAYTTYGTNTGYTCNGTNYTNCCNTCNCAYTGGMGNTCNAAY AARTCNYTNCCNATHTCNTTYAARGTNGTNGCNYTNGGNGARGTNAARGAYGGNACNAAR GTNTGYATHACNGCNGGNAAYGAYGARAAYTTYTGYTCNGARATHMGNAAYGGNACNGCN GTNATGAARAAYCARGTNGCNAARTTYAAYGAYYTNMGNTTYGTNGGNMGNAGYGGNMGN GGNAARAGYTTYACNYTNACNATH------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGYTNACNATHACNGAYTTYGTNAAYATHYTNAARMGNTAYTAYAARTCN CCNTCNACNCCNATGGAYGARYTNGARGAYCAYAARATHGCNACNTGGMGNGARGTNYTN AARGAYCARCARAARCCNYTNGTNCARATHAGYCCNGAYGCNAGYYTNTTYGAYGCNATH CARACNYTNGTNGARAGYCAYGTNCAYMGNYTNCCNGTNATHGAYGAYAAYACNGGNAAY GCNATHTAYATHYTNACNCAYAARMGNATHYTNMGNTTYYTNCAYYTNTAYYTNAARGAY YTNCCNMGNCCNCCNTTYATGCARCARACNATHAARGARYTNTCNATHGGNACNTTYAAR GAYGTNTTYACNGTNGARCCNGAYACNCCNYTNATHAARGCNYTNAAYATGTTYGGNGAY CAYMGNATHTCNGCNYTNCCNGTNGTNGAYAARAGYACNGGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARGARTTY GCNAARGCNGCNMGNATHTTYMGNCCNYTNTCNGCNYTNATGTCNTCNMGNTTYGTNAGY GGNTCNATGATHGAYGAYGARAARACNGAYGGNCARACNYTNTCNCAYAGYGARAARAGY GAYCARGCNAARGCNGCNGARATGAARATGTTYGGNAARYTNACNMGNGARGARCAYGAR TGGCAYCCNGAYAARYTNYTNTGYAARMGNTTYAAYGTNCCNCAYCCNTAYCCNGGNTCN ACNATHGTNGGNYTNACNACNGTNAARMGNAGYAARTAYTCNYTNTTYAAYTTYYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARYTNAARGARTAYGGNATHGGNTTYACNAAYATHTGYGCNMGNACNACN MGNGGNAGYGCNGAYYTNAARMGNCCNGARATHAARGARGGNGCNGARATHYTNMGNGAR AARYTNATHAARTAYAARCCNAARATHGCNGCNTTYAAYGGNAARGGNATHTAYGARGTN TTYTGYGGNCAYAARAAYTTYCAYATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARMGNGCNMGNAARMGNYTNYTNAARGARYTNCCNAARGTNGAR GARGAYGTNAARCARGCNGTNGCNAARTGGGARGARAARCAYGGNTGYCAYTTYTTYGTN AARGGNYTNMGNTTYCCNGAYTAYGTNGARAAYCARTGGGCNGAYTTYCAYGARCARAAR GARCARCARAARCARACNMGNATHAARGCNMGNGCNAARCARGCNGARACNGARATGYTN TAYGGNTGYAARACNACNGGNAAYACNCCNYTNAARMGNMGNACNCCNGCNATHTCNACN CCNCARMGNACNCCNYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MGNGCNAARTCNTCNGARTTYATGGARGTNACNGTNGAYGARTTYGGNTCNGTN TCNGARYTNATHMGNGGNMGNGTNAARYTNGGNGAYGTNAAYTCNACNTAYCAYGCNYTN TGGCARCAYTTYMGNGARGARGGNCAYTCNGARCCNYTNACNCCNAARGARATGACNGCN AARGGNYTNMGNGTNACNGGNGCNACNGGNGARGCNAARYTNAARGTNYTNMGNGCNYTN MGNYTNTGYCAYATHTCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TCNGAYGCNGCNTGGAARAGYGAYYTNGAYTTYYTNTAYTCNCCNGARMGNGCNGAY ATGAGYGAYATHATGAGYACNGTNAAYGTNTCNGCNTAYACNAAYGGNACNCAYGTNAAR YTNCCNACNCCNAARGCNCCNCCNGGNGGNTGGACNAAYGARGAYGGNGTNAGYGTNGCN TTYGTNAAYTTYTGYTCNGCNYTNATHTGYTTYTCNGTNMGNTAYGCNTCNGTNTTYTGG TAYACNAAYAARACNYTNACNYTNYTNTTYGCNTGYYTNYTNYTNTCNATGACNGTNAAY TCNGTNTTYGGNTTYAGYAGYTTYTCNATHYTNTAYAARGTNTGYTAYAGYYTNTCNYTN TTYCCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ACNYTN GCNCAYATGATH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GAYAGYGGNGARYTNGAYGTNAARMGNGCNTTYCCNMGNTGGMGNMGNAAYGTNAAYCAY YTNTGGCARGTNYTNYTNCAYGCNMGNAARATHTTYTAYAARATHGARAGYAARAGYCCN YTNAAYCCNGARGCNGCNGTNYTNTAYGARCARGARCCNGARYTNTAYAARAAYMGNGTN GCNGARTCNYTNGCNTCNGCNAARGARMGNYTNTAYCARCCNCCNGAYYTNGAYGAYCCN TTYGCNYTNMGNTTYAGYCCNTGGAAYGARGCNGTNCAYCCNGARGCNAARAARCARATG CAYCARYTNTCNCARGTNMGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TAYAAR---------AARGAYCAYAARMGN---------MGNACN TAY------------------------------GCNGGNATGGTNTCNGCNATGGAYGAR GGNGTNGGNAAYGTNACNCARGCNYTNAARGAYTCNGGNYTNTGGGAYAAYACNATHYTN GTNTTYTCNACNGAYAAYGGNGGNCARGTNCAYGCNGGNGGNAAYAAYTAYCCNYTNMGN GGNTGGAARGGNTCNYTNTGGGARGGNGGNACNCAYGGNGTNGGNTTYGTNACNGGNCCN CCNGTNAARAGYAARGGNGARGTNAGYCAYGARYTNATHCAYGTNAGYGAYTGGTTYCCN ACNTTYGTNCAYYTNGCNGGNGGNTCNYTNAAYGGNACNAARGAYYTNGAYGGNGTNAAY CARTGGATGACNATHACNGARGGNTCNGARTCNCCNMGNAAYGTNYTNYTNCAYAAYATH GAYGTNYTNGCNCAYMGNAARGGNGAYMGNYTNTAYAAYGAYACNTTYGAYACNMGNATH MGNGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CARCAYMGNYTNTCNGGNCARAGYTAYGARTCNGGNGTN TCNTCNMGNCARAGYTAYCAYAGYACNTCNAGYTCNTCNYTNGGNAGYYTNGAYMGNYTN GARGARCCNGGNTTYACNTCNACNATHAAYGTNGCNCARYTNACNCARGCNGGNGTNCCN GAYCAYGARGTNYTNCAYGCNTGGYTNAAYGAYYTNMGNTTYGARGARTAYAGYCCNYTN TTYACNCARGCNGGNTAYGAYATGCCNACNATHTCNMGNATGACNCCNGARGAYYTNACN GCNATHGGNATHACNAARCCNGCNCAYMGNAARMGNYTNAARGCNGARATHGCNMGNYTN AAYATHCAYGAYGGNATHCCNGAYTTYMGNCCNAAYGAYYTNATGGARTGGYTNCAYYTN YTNGGNYTNGGNATGTAYTAYGARACNYTNTGYGGNCARGGNTAYGAYGAYATHGAYTAY GTNACNGAYATHACNTGGGARGAYYTNGARGARATHGGNATHAARAARYTNGGNCAYCAR AARAARATHATGYTNGCNATHGAYMGNYTNAARMGNATHACNGCNGGNGCNAARMGNYTN TCNTCNGTNGARGGNMGNMGNCCNTCNYTNGARYTNYTNGARCCNCCNCCNCCNGCNCCN CCNATHACNMGNTGGTCNGGNGARATHACNGCNATHCCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNYTNGAY TCNTAYAARGCNTTYGTNGTNGTNTAYAARGARGGN---GAYGTNTCNYTNAGYAAYCAY TTYGAYAAYGCNGARATHACNATHAAYGTNAGYYTNAAYTCNGAYTAYGARGGNGGNGAY YTNTAYTTYGGNAAYATGTGGGGN------GARGARACNTCNCARTCNAGYCCNGARGCN TAYACN------CAYATGYTNGGNGTNGGNGTNYTNCAYMGNGGNYTNCAYATGCAYGGN GCNYTNCCNATHACNMGNGGNTCNMGN--------------------------------- ------------------------------------------------------------ ------------------------GGNAGYTCNCCNTAYACNTCNAGYACNTGGMGNAAY GCNGCNACNYTNGGNYTNATHTAYGGNAGYACNMGNTAYYTNMGNAGYCAYCCNTAYGGN MGN---ATGCCNCCNATHTGYACNAAYMGNTAYGAYGCNATGYTNGAYGGNAARGTN--- ---TAYTTYATHTGYCCNAARATGGGNGARCCNTCNAGYTAYACNTGGTGYTGYGGNCCN GARGAYMGNGARTTYTGYTGYAAYGCNAAY---------------------CAYTAYAAR CARAARAARGGNGGNYTNTCNACNGGNGCNATHGTNGGNATHATHATHGCNATHATHGTN TTYATHGTNYTNATHGTNTGYTGYTGYAARMGNTCNGGNAARGGNGGNAARATHATHMGN AARTTYTCNAARAARGARCAR------------GAYAARGCNGGNGGNCAYCAYCAYGCN GGNCARCCN---------AAYGGNMGNAGYGGNGTNTTYATGTGGCCNGGNTCNGARGCN ATGATHAARTGGATGAARCCNACNTTYACNGTNCCNTAYGAYGCNGGNGTNTCNAAYMGN ACNMGNGTNGAYMGNGTNGTNGGNTGGYTNTCNAAYAARCAYCCNGTNAAYYTNGGNATG YTNTAYTTYAAYCARCCNGAYCAYACNGTNCAYACNGTNGGNCCNGARTCNAARGARMGN MGNCARYTNGTNCARGCNYTNGAYGARGTNGTNGGNTAYYTNYTNCARMGNATGGARGAR GARGAYATHYTNGAYGAYGTNAAYATHATHATH--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CCNCARATHYTNAAYAAYAAYAGYCARGTNAARGTNAARAARGARGGNAGYTCNAGYCCN GARCCNCARTTYGAYTAYGGNTCNGCNTTYYTNGGNCCNAAYYTNTGGGAYAARACNTAY AAYAAYGAYTTYAAYYTNGARTAYATGGAYYTNGAYGARTTYYTNTCNGARAAYGGNATH CCNGTNGTNGARGAYGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AAYACNTAYAAYGAYCCNGCNMGNTAYACNCARAAYGAYYTN TAYAAYGTNGARGAYGGNGGNGTNGTNAARAARCCNMGNCCNGTNAGYGCNGTNYTNYTN MGNGARGGNGAYGCNTAYMGNTCNMGNCCNMGNAGYGGNCAYACNACNGAYGGNGGN--- GAYAARCARGTNTTYATHACNCARAARGTNGARMGNCCNYTNAARTAYGARACNACNMGN CCNGTNTCNGCNAARCCNAARCCNTCNTCNGCNCAYCARMGNCCNGTNTCNGGNAGYMGN CARGGNAARMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TAYYTNGAYYTNMGNYTN CCNYTNCCNYTNATGAAYATGGCNGGNCCNGGNCCNTAYCAYGAYGAYATHTGGCCNGCN GARGARGGNACNCARGTNCAYMGNGCNTCNTTYYTNYTNCAYTTYAGYYTNAARTTYTGG CARGGNGTNMGNAARGARAARACNATHCCNCARMGNGAYAARAAYGAYMGNCCNYTNTGY ATGTAYCARTTYCAYMGNYTNTTYAGYACNTGYMGNATHCCNGGNGTNCARAGYGAYCAY YTNGCNGARTAYTTYAARACNCARTCNGARGGNAGYACNCCNACNAAYATHGTNGTNYTN MGNAAYGGNCAYATHTTYTCNGTNGARGTNGTNGAYGARGAYGARGARGTNATGACNCCN CCNGARYTNGARYTNGTNYTNCARCARATHGTNGAYAARTGYAAYGCNYTNGGNCCNGGN CARGARYTNGGNTTYYTNACNACNGAYAAYMGNACNAARTGGGCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATHATHATHACNATHTCNATHATHATH ATHATHATH---GTNGTNGTNATHTAYTTYTGYTGGTAYMGNMGNMGN---GGNAARGAR GARTCNTAYGCNGAYATGAGYAGYAARCCNTCNAAYAAYTCNAAYTAYGCNAAYCAYCCN CCNCCNGTNGTNTAYACN------------------ACNGAYACNGAYGAYAARGCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYGAYGAYMGNGARGARYTNATHMGNYTNATHCARGARGCNGAYCARCAYYTN ATHYTNATHACNCAYGGNACNGAYACNATGTGYGARACNGCNCAYTAYYTNGTNMGNYTN GGNGTNGGNCARGGNACNAAYTTYGAYCCNGGNGTNGGNGGNAARGTNGTNGTNATHACN GGNGCNTTYMGNCCNGARMGNYTNAARGAYTCNGAYGCNGAYTTYAAYGTNGGNTTYGCN YTNGGNGTNYTNCARATGGCNMGNCARCCNGGNGTNCAYGTNACNATGGGNGGNTCNGTN GTNTCNGGNAARCAYGTNGTNMGNGAYACNGARGGNAARTTYGGNGAYGARMGNGARYTN ATH--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GTNAAYCAY ATHYTNATHAAYYTNGAYATHMGNACNGCNGCNGARATHGARGCNGAYGCNGARGAYGAY GAYGAYGAYAAYCARGAYYTNTGGTCNGGNTGYYTNGGNYTNTGYTGYTGYATHTTYTGY ATHGGNYTNCAYGARAGYYTNACNGARACNAARGTNGAYAAYTCNACNGGNYTNACNTCN GARYTNAARGGNATHTTYGARGAYGTNAARMGNGCNTTYGAYAAYGAYGTNACNCCNTTY TTYGCNYTNTTYATHTGYTGYTGGGGNACNGTNTTYYTNGARYTNTGGAARMGNCAYMGN TCNTCNYTNGCNTAYGARTGGGAYGTNGAYCARTTYGARGAYAAYGARCCNGAYMGNCCN CARTTYTTYGGNACNTCNGTNAARCARGAYCCNGTNACNTCNGCNTCNGTNYTNATHYTN ATGATGATGGTNGTNGTNATHAGYGTNGTNGCNGTNATHATGTAYMGNGTNATHATGAGY GTNGAYTAYTGYCCNGAYATGGAYGARMGNGARTGYTTYYTNYTNACNACNGTNATHNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNYTNNNNNNNNNNNNNTAYGAYAARYTNGCNATH ATHYTNACNGAYTGGGARAAYCAYMGNACNCARACNMGNTAYGAYGAYGCNYTNATHYTN AARYTNTTYGCNTTYCARTTYGTNAAYAGYTAYGCNTCNTGYTTYTAYATHGCNTTYTTY MGNGGNCARYTNTCNTTYCARGTNATGATHYTNATGYTNGCNAARCCNTTYCCNAARTTY TTYAARGAYATHATHYTNCCNTTYGCNMGNAGYGTNTGGMGNAAYCAYATHAAR---CCN TGYTGYGGNAARAGYAARGARGAYCARGARAARGAYACNAARGGNGTNGAY--------- CAYCCNACNCAYGTNAAYTTYYTNGARMGNGARMGNYTNAARCCNTCNYTNGGNGAYTTY ACNCARGGNGARTAYACNGARAARATHATHYTNTAYGGNTTYYTNATGYTNTTYGCNACN TCNTTYCCNYTNGCNCCNYTNYTNGCNYTNGTNATHTGYTAYATHGAYATHMGNGTNGAY GCNAARMGNATGYTNTGGTGGTAYMGNMGNCCNATHATHGGNATGTGGTAYGARATHYTN CARTTY------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATHATGACNGARTTY GTNCARATHGARATGATGTTYCAYGCNMGNGCNGAYYTNGARGAYTTYMGNTCNGCNYTN YTNGAYGCNTCNGGNYTNTCNMGNTCNTTYACNGGNATHGCNYTNAARTAYCARGTNACN GTNGARCARATHAARMGNGAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MGNCAYGTNATHAAYGCNATHGAYAARGTNMGNAARTGGGARAARMGNTGGGTN ACNATHGGNGAYACNTCNATGACNATHTAYAARTGGGTNCCNGTNACNGTNCARGARAAY CCNGGNGCNYTNMGNAARATHCCNGGNGTNAARACNAARACNCAYTCNAARACNMGNYTN TAYMGNGAYGARAAYTCNAAYGGNATHGAYTCNATGTCNMGNGGNAGYGCNGGNTCNCCN GCNGARTCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CAYCCNAAYAAYGTNYTNYTNGCNGCN GGNTCNACNGAYTTYAARTGYMGNGTNTTYTCNGCNTAYCARAARGARGTNGAYGARAAR CCNGGNCCNTGYTGYTGGGCNACNAARATGCCNTTYGGNAGYYTNATGGCNGARTTYAGY AAYGGNGGNGGNGGNTGGGTNCAYTCNGTNTCNTTYTCNATGAGYGGNGAYMGNGTNGCN TGGGTNGGNCAYGAYTCNAGYGTNACNGTNGCNGAYGGNACNAARGGNCARCARYTNGCN GTNATHAARGARAGYTTYYTNCCNTTYMGNGGNGTNACNTGGGTNACNGARAAYAGYYTN GTNGCNGCNGGNTAYGAYTGYAAYCCNATGYTNTTYACNTAYGAYGCNGGNCARATHACN YTNGTNAGYAARYTNGAYATHCCNCARGARAARGARACNGGNACNATGAGYGCNATGAAY MGNTTYAARAAYYTNGAYAGYAARGCNTCNACNGGNAGYACNAGYACNGAYYTNAARACN CARCAYCARAAYACNGTNACNCARGTNTCNGTNCAYACNGGNGAYAARGGNAAYGCNACN AARGTNGCNACNACNGGNGTNGAYGGNAAYYTNATHACNTGGGAYYTNAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYGTNGCNTCNGARAAY YTNTAYGAYMGNMGNATHGGNGTNGTNATHTTYGARTTYMGNAGYTGGYTNGAYACNYTN GAYGGNGTNGTNTAYMGNAGYCARAGYCAYACNTAYYTNCARTAYCARTCNAAYMGNAAY ACNYTNGGNTAYTAYGTNGAYACNACNTGYGAYGCNYTNGGNGGNGTNTTYYTNTGYGTN GGNGTNYTNTTYTAYYTNTTYAARMGNTTYGAYCCNTAYAARCARGAY------YTNCCN ATGTGGAGYAARGCNCARGARGTNGCNTCNAARGGNGGNTCNCCNACNAAYGGNCAYCAY GTNAGY---MGNGARACNTAYAGYAARAARTGYYTNTTYTGGAARTGYTGGTGYTAYGGN GTNGCNYTNGCNYTNGCNGGNAARTTYTGGGAYYTNGCNGTNGGNGAYTTYAARGAYATH TTYCARGTNGARYTNAARGAYCCNACNYTNTCNGTNCARCARTTYGARYTNTGYCAYTCN ACNACNACNYTNTTYATHTGGTAYYTNTGGMGNYTNYTNGARGGNCARGCNATGYTNCAR TAYATHYTNATHGGNATHTTYATHGAYAARATHTGGGARYTNYTNAAYTGGACNCARTAY ATHYTNTTYTTYATHGTNTGYAGYYTNTAYGTNGTNACNYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TCNGAYYTNGARGGNGARATHATHCCN AGYCCNACNAGYACNCCNGAYMGNAGYGGNMGNAGYGCNGARMGNGAYTAYGGNGARYTN GGNATHYTNGGNATHGGNMGNTTY------------GGNGGNMGNCARCCNCAYYTNAAR AARCAYGGNTAYAAYTCNGAYGGNGAYGAYACNCAYACNTCNGGNAGYAGYGAYAARATG GGNGAYCARGTNATHCCNGAY------------GARATGAAYGAR------------AGY ATHMGNCARYTNCARGGNACNGTNAAYGTNGAYCAYYTNYTNTCNAAYTTYMGNAAYCAR MGNMGNYTNATHGARTCNMGNTAYCARCARYTNAGYGAYGARGGNYTNGTNGAYAARGTN TAYAAYATHYTNACNAGYGARGAYCCNAAYGARCARGCNCARGGNATHYTNGCNGARGTN AGYGCNCARGARAARCAYATHMGNGARCARAARGCNYTNGGNATG---AARYTNGAYTCN AAYTTY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNGAYTCNTGGTCNGTNATHYTNAAYGGNGARGTNGARATHGTNMGNCCNGAY GGNGCNAARGARMGNYTNCARATGGGNGAYAGYTTYGGNATHAGYCCNACNATGGARAAR YTNTAYCAYCARGGNGARATGMGNACNATGGTNGAYGAYTGYGARACNGAYCCNGCNATG TGYGARTTYYTNGARCAYTTYGARTGYGTNYTNGARGCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHTTY AARGAYAARAARTCNAAYGAYGARATGTTYAGYGAYGCNTTYAARGTNGTNATGGAYGGN ATHGCNTAYMGNGTNCARGGNAARTTYGTNACN---CAR---TCNACNGAYGTNGGNCAR GTNGAYATHGGNGGNAAYGCNAGYCARGARGCNCCNGARGAR---CARGCNGAYGTNATH AARGTNTCNGGNGTNGAYGTNGTNYTNTCNTGYAARYTNAAYGARACNTTYTTYAGY--- ------GAYTTYAAYACNTAYGTNAARACNTAYTTYAARGARTTYTGYAARAAYCARGTN GARGGNYTNGARGAYGARAARCARGARAARTTYAARGARGAYATGAARACNTTYGCNAAR TTYGTNAARAGYAAYTTYAGYGARYTNCARTTYTTYCARGGNGARTCNTAYAAYGAYGAR GGNTCNYTNGGNTAYYTNATHTAY------GAR------------------GAYGARGTN CCNTGYYTNTAYTTYATHAARGAYACNYTNATHGCNGARAAR------YTNGGNTCNMGN GCNCARACNGARYTNGTNGAYATHATGGAYGARTAYAARAGYGGNAAYTTYACNATHAAY GAYGCNAAYATGYTNTTYATGTCNTGGAARCARMGNTAYGCNTCNGGNAAYGCNGTN--- AGYTTYAARGAYAARCARAGYTCNYTN------------------GCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYGARGAYACNGARGAYGCNAGYGARACNGAR GARACNAAR---CARAAYAARTTYACN------------------GGNCARMGNACNGAR ATHAARGARMGNATGTAYCARGAYAGYYTNAAYCARYTNAARAARCARATGATGATGYTN CARGARGGNTCNYTNCCNGARTTYATHAARMGNAAYAARAARATHGARATHCARTAYMGN GARMGNATHMGNGTNAAYGARATHATHAARCAYYTNGARATHGARATGATHGARMGNGAR TAYACNAAYGARAARAARAAYATHGCNAARGARTTYGAR--------------------- ------------------------GARAARAARATHGAYYTNAARGARAGYYTNYTNGGN GARYTNMGNGARAARMGNAGYGCNGTNGARCARGARMGNCAYAAYATGGAYYTNAAYGGN GCNGAYTTYATGGAYGTNAARCCN---YTNACNMGNAARYTNMGNMGNMGNCCNAAYGAY CCNYTNCCNGTNCCNGARAARMGNMGNAARCCNTCNCCNGCNCARATGAAYATHCARYTN GARGARGAYCARGTNAAYGARGAYATHYTNYTNYTNACNAARYTNACNGGNAARCCNYTN TCNAARAARTCNACNCARCCNCARAGYCCNGCNYTNTCNYTNTCNTCNYTNGAYGTNMGN ATHGARGAYGGNMGNYTNTGGTTYGAYAARAARTGG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CAYCCN CCNGGNATGAARCARTCNGTNYTNATGYTNTTYACNAARYTNYTNTCNMGNYTNCAYCAY CCNYTNYTNCCNCAYGTNAAYGTNCAYMGNGCNGTNCARMGNATGATHAARGCNTGYGGN GARACNAARGCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CAYGARATH GTNCCNGGNAARTTYAAYGARCAYGAYTGGAAYATGATGGTNGAYMGNGAYAGYTCNGAR GARTTYGTNATGGARATHATHGAYAAYYTNATGGAYACNACNATGTCNACNATHTAYAAY CARTAYATHGARAARCARYTNYTNCCNTAYACNATHACNCARGCNMGNGAYGCNATHGTN GARATHATHGARTGGCARTTYYTNTCNMGNGAYGARGGNGARATGGAYATHCCNAAYGAY AAYGGNTGGGCNGARGAYGARGARCCNGARCCNGCNGTNACNGAYTGYTGGGCNCARGGN TCNGTNCCNAARACNTAYATHMGNCCNGARTCNCCN------------GTNYTNGARAAY ATHCCNGAR------GARCARGGNYTNGARGARGARACNAARYTNGARCARAARGCNGAR GARGARGARACNMGNGARGCNGTNGARATGGARGAYCAYGTNTCNGAYACNGARGTNGAY GCNACNGCNAGYCCNGAYAARAARGTNGARYTNAARGARGTNCCN---------AARCCN CCNGARGAYGGNAARMGNAAR---AARAARCCNTTYMGNCCNTAYGCNGGNAARGTNGGN TCNGCNAARTAYACNAARATGACNCARAGYYTNGAYGARACNGARATGAARATHYTNGAR CARGARTAYATHGCNTCNATGCCNCCNTCNGARGARAARCCNAGYACNYTNYTNAAYATG CCNGCNTCNTGYAAYTCNATHYTNAARGTNCARTCNGGNMGNCCNCCNGGNAAYAARGAY GTNGTNTAYGAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNTCNCCNCCNYTNCCNAARMGNGGNGCNTAYAAYATHGAYTGGGAYAAY TTYGAYGAYAGYGTNAAYCCNTTYCARAGYGGNACN------AARATHGGNTTYTCNCCN CCNAARTCNGAYGCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGGMGNATH ATHAAYYTNATHATGACNGTNTTYTTYATGYTNGCNGCNYTNGCNAAYYTNAAYGAYAGY GAYTGGTAYYTNTGGGTNCCNGCNTAYATHYTNCCNGGNYTNYTNAGYYTNGTNGTNGCN YTNGTNCCNTCNGTNGCNGARACNAGYCCNTGGAGYGTNAGYTGYGTNATHYTNTTYACN YTNTAYYTNGCNTAYAGYYTNTAYCARGTNGTNGARYTNATHACNGCNATGGCNGGNMGN GTNGCNAAYCCNYTNTCNCAYGARGARGGNMGNGARYTNGGNGGNYTNATGATHATHATH ACNTGGYTNGGNATHAGYMGNTTYACNTCNYTNGGNMGNCCNGAYAGYGTNAGYAAYMGN AGYYTNATGAAYGCNYTNYTNYTNATGACNATHACNYTNTCNGTNYTNCCNYTNTTYACN TGGTCNYTNTGYTTYGTNGGNGAYTGGCAYMGNMGNYTNGGNCAYTGYAAYAAYATGTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CAYAARCARACNCAYTGYGAYAARAARAGYTTYCCNTGYCCNGTNTGYGGNAARYTNTTY GCNACNAARTCNTAYGTNTCNATHCAYATGAARTTYCAYCARGARGAYMGNAARTTYGTN TGYGARGGNTGYGAYAARMGNTTYTTYMGNAARTCNGAYGTNGTNAARCAYMGNMGNATH CAYACNGGNGARAARCCNTTYCARTGYGCNGCNTGYGGNAARATGTTYTCNTTYGCNAGY TCNYTNTAYACNCAYCARMGNATHCAYGCNGGNGAYAARMGNTTYGCNTGYGGNGARTGY GGNMGNGARTTYACNCAYAARCAYCAYTTYYTNATHCAYAARAAYAAYCAYTCNGGNCAR AARCCNTAYGCNTGYGCNCARTGYGGNMGNTCNTTYYTNACNAARCARTAYYTNAARAAR CAYATGGTNACNCAYACNGGNGARAARAARTAYACNTGYGCNCAYTGYGGNGARAARTTY ACN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AGYGGNTTYYTNMGNAARAARGGNAARAARGAR AARYTNGCNCAYTCNATHYTNAARTGGAGYCAYMGNTTYGTNGTNATHGCNAAYAGYAAY GTNTAYTGYTAYCCNAGYGARYTNGCNAARTCNCCNAGYTCNACNGTNTCNYTNGTNGGN TAYAAYAARGTN------------CARMGNGARTCNGAYAARAAYTGYTGGTGYTTYGTN GTNAARCCNGCNTTYCARAAYYTNMGNACNYTNACNTTYGCNTGYGCNAGYGAYGTNGAY MGNAARGCNTGGATGACNGCNTTYMGNCARGARATGYTNYTNGCNAAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARCCNGGNYTNGCNMGNGAYGGNACNATGCARGTNACNGCNAARGARGGNATHGAYTAY YTNAARGGNGARGGNCAYACNAARYTNYTNAARGCNCARGGNYTNATGGARGAY------ ------------------------------------------------------------ ------------------------------------------------AARGCNGGNATG AARMGNGAYGGNACNATGGCNGTNACNGCNAARGARGCNGARMGNYTNYTNGARGGNGGN AARCCNGAYGCNGAYGCNCARACNMGNGGNCARCARAARCARATHGARGARATGAARAAR GARAARCCNGARCCNCCNGCNAARAARGTNAARYTNGCNAARGAYAGYACNATGGCNGTN ACNGCNAARGARGCNAARGGNATHYTNGCNGGNGARAARYTNGGNGAYACNMGNCARGAR ACNACN------AARGGNAARAGYAARAARCCNATGMGNAARAAYATGACNATHGCNGCN ACNATGGCNGARGCNAARTAYGTNYTNGAYGGNGARATHGAYYTNAAYGCNGGNMGNAAR ACNMGNTCNCARAGYMGNGGNGTNACNCCNAARCCNGCNGTNAARMGNGCNGGNACNATG CARAARACNGCNAARGARGGNAARGCNTAYYTNAARMGNGGNAARAARGGNAARAAR--- ------------------GARGARGAYATHYTNGAYGARTTYGAYGAYATHGAYTTYGAY MGNYTNTCNTCNCARGARGAYAGYTGGYTNTAYTCNTCNCCNAARGCNYTNACNCCNCAR CARAGYCAYAARACNGTNATGAAYTGGGTNMGNGARGARTTYGAYCAYCCNAGYCCNGAY GTNYTNTCNTCNMGNMGNGCNYTNYTNTCNMGNYTNGAYGARGCNGCNMGNATGAAYMGN AGYACNAGYTCNGGNTTYGAYTCNGGNACNTTYACNMGNCCNAARMGNACNMGNGARGAR GGN------ATGCARTCNGARGTNTCNGCNYTNCCNAAYYTNCCNAAYGTNAGYGAYATH CARAAYYTNGCNAARCARCARGARGARAGYYTNMGNCARAGYATGTCNCCNGCNMGNAAR GGNATGAARGCNAARAAYCARGTNGTNGAYGGNGARGGN---TCNMGNATGAGYCCNAGY MGNTTYGAYATGGAYGGNGCNTAYATGGCNCARMGNAARGGNAGYYTNGGNTCNGAYCAY AGYACNCCNCCNGAYAGYCCNCAYGCNTCNCAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GCNCAYACNGARGTNGTNACNGAYGAYGAR GAYGGNYTNCARCAYACNGGNTAYGGNCAYGGNGAYCAYAARAARAARMGNGGNYTNMGN MGNYTNTTYGGNAARYTNAARMGNAGYAGYTCNCARGAYTTYGARGGNGGNMGNGARMGN GGNGAY------GGNGCNTTYGTNMGNGGNGGNGTNMGNGCNACNGCNTCNGCNMGNYTN GCNTGGTCNMGNGAYCCNAARGGNMGNATHAAYGAYAAYGAYGTNCCNTTYACNMGNTGG GAYACNGAYMGNGTNACNGCNTGGATGAAYGAYYTNGGNYTNAAYATGTAYYTNGTNGAY TGYAARMGNTGGGTNMGNAAYGGNGARCARYTNYTNMGNTGYTCNGTNCAYGAYYTNGAR AARGARYTNGGNATHAARAAYCCNYTNCAYMGNAARAARYTNCARYTNGCNYTNCARGCN ATGGGNTCNGARGTNAGYGAYMGNATGATGGARYTNGAYCAYAAYTTYGTNGCNMGNTGG YTNGAYGAYATHGGNYTNCCNCARTAYAARGAYGCNTTYTAYGAYGCNMGNGTNGAYGGN MGNATGYTNCAYTAYYTNACNGTNGAYGAYYTNTTYTCNYTNAARGTNTCNAAYGARYTN CAYCAYGTNTCNATHAARMGNGCNATHCARATHYTNMGNYTNAAYGGNTAYGAYCCNTCN TGYYTNMGNMGNMGNCCNATGCCNGAYGARCARGTNYTNACNAARGGNATHCCNGGNGAR ACNGTNYTNTGGACNAAYCAYMGNGTNATGGARTGGYTNMGNACNATHGAYYTNTCNGAR TAYGCNCCNAAYYTNMGNGGNAGYGGNGTNCAYGGNGCNYTNYTNGTNYTNGARCCNMGN TTYAAYTCNGARYTNTTYGCNYTNYTNYTNTCNATHCCNTCNAAYAARACNYTNYTNMGN MGNCAYYTNAAYACNCAYTTYATHAGYYTNATHGGNCCNGARACNCARACNMGNAARMGN GARGCNGARGCNCARCARGGNTAYGTNCCNYTNYTNCCNAAYAAYAARATHAARAARGGN AARTTYGGNATHTTYGGNCAYAARMGNAGYMGNTCNGARCCNGARACNGARGGNYTNGTN TGYCCNATHGAYCARGCNGGNGGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNTGYTCNCCNACNCARAARYTNTCNACNAARCARATH TGGAAYCAYYTNTCNACNYTNTAYGAYYTNCARGCNYTNAAYGARTCNGARTGYATHCCN TTYCCNAAYAARGARGCNGARTTYCARYTNYTNACNTCNGARGTNGCNGAYYTNACNCCN AARTCNTTYCCNMGNTGYCCNTAYYTNAGYGAY---GAYAGYAARCCN------------ GAYGCNATGTCNAARGGNACNCARAARGCNATHAARCARGARAGYMGNACNAGYCARCAR AAYTCNAARGCNGAYTCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYGAR AARTAYMGNGARGARYTNMGNAARATGGARAARGARMGNAARGARGCNCARGARAARTCN AGYGTNGCNTTYAARTCNYTNGARTCNGARTAYGARACNGTNAARTCNAARYTNGARGCN TCNAARACNMGNAAYAARGTNYTNTCNAAYGARATHTCNACNYTNAARAARCARGTNCAR GTNYTNYTNAARAARGARACNAAYGAYAAYGARYTNATHGARGCNYTNATGAAYCARCAR GCNCAYYTNAARAARYTNYTNGARCARTCNAGYCARAAYAARAAYGARCAYCAYCARYTN CARCARCARCARATHCARCARYTNGCNATGAARACNCAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNATHGAYYTNGARGARTTYATHAARATGACNYTNAAYAARTCNGCN AARGAYCARAARMGNYTNYTNGGNYTNCARAARGAYTTYAAYACNTTYATHCARGAYGTN GGNCAYAARTCNYTNAARYTNCCNGAYATGAGYTCNTAYGAYMGNATGYTNGTNCAYMGN GTNGCNGCNTTYTAYGGNYTNGAYCAYAAYATHGAYCARAGYGGNAARGCNGTNATHGTN AGYAARACNGAYTTYACNMGNGTNCCNGAYTTYAAYTTYAGYGAYCAYATHTCNMGNAGY AGYYTNGAYTGYGARCCNAARAARATGATHYTNAARAARAARCCNGCNAGYYTNGAYGAR ------GGNMGNGGNATHGAYAARTCNCARTTYAGYATHCAYAARGCNAARTCNTTYGAR GARMGNCARCARCAYTAYACNGARACNMGNAARMGNATHTTYCARAAYCARCCNCAYTCN TCNCAYTCNCARAAYYTNAAYACNTTYATHTCNTAYAGYAAYGTNYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNGAYTCNTGGGARAARAARAARMGNCAR GAYMGNGARGCNYTNGARGCNAAYGGNGGN------ATHGTNACNGCNAARGCNGTNAAY GGNTGGGTNAARGAYAARGAYCCNAARGCN------------AARGARGCNAARCCNGCN AARAARAGYGGNMGNGGN---TCNMGNTTYTGGMGNMGNAARAARAARCCNGAYGAYGAY GGNGARGGNMGNGCNGARGAYGARGTNGARCCNGCNYTNTGYMGNGGNATGATGGAYGTN ATGACNCARAGYAAYAGYGTNAGYGCNGAYYTNGARATGGTNGAYCARGAYATGGAYGCN ATHGTNGCNATGGARMGNGAYATGGARYTNGARAARGARACNYTNYTNYTNAARGTNYTN GCNATHYTNYTNMGNAARAARGCNGAYAARMGNGARGTNACNCARCARTTYGTNCARAAY TTYGTNAARAARACNGARGGNGARGTNMGNGAYYTNMGNAARATGATHGARMGNGARAAR GARGARGCNGARGARGARYTNAARAAYAAYCCNAARYTNAAYAARGAYTCNCARGCNATG GARACNGARATGCARAGYYTNCARACNAARTTYAAYAAYAARCARGCNAARYTNCARAAR GAYTAYAARGARAARATHMGNYTNGAYYTNYTNMGNTCNTCNGGNYTNGGNGARGCNGAR GTNGARGARYTNATGGARAAYYTNATGGCNAAYATGGCNGCNGTNGARGARAARYTNGGN YTNGARCARGCNMGNCARMGNMGNAAYYTNGARGARMGNYTNGCNMGNMGNAARCARGTN GTNGARTAYACNGARATGGARGARAARGARGAYAARAARGARAARGAYGARMGNGTNCAY GCNTTYTCNGAYYTNYTNAGYAARCARGTNMGNGARGGNAAYYTNYTNGARMGNCARNNN GAYCARYTNACNAGYGAYTAYCARTGYGAYYTNGAYGAYATHCAYAARTAYCAYTTYGCN GARATGGARCARCARAARTTYGAYYTNGCNGAYGTNATGAARCARGTNMGNYTNAARAGY TTYATGCARYTNGAYAARAARCAYGARAARGARMGNGCNCARYTNYTNCARACNGCNGAY AARAAYGGN---CCNGCNGARTTYGTNAARGTNTAYCAYGARYTNATGGCNMGNCARCAY ACNGARAARGARAAYYTNAGYAAYGARCARGAYCARAARGARACNCARGCNYTNGAYAAR YTNMGNCARGARATHAARAARAARGARAARGCNGCNATGGAYAARGARGCNGTNACNATH GCNGARAARATGGARAGYACNTCNGAYGTNACNTCNGCNGARGTNGAYMGNYTNYTNAAR YTNCAYMGNCARMGNATGGARGCNTAYAAYGAYAARMGNCARMGNGARAARCARGCNTCN YTNGCNMGNYTNCARGARAARYTNCARCARMGNATGACNGARGCNGAYGARGCNGGNGCN MGNGAYCARAARGARCARGARACNYTNAARGARGARCARATGGCNACNYTNAAYAARGTN YTNGCNTCNAAYATGGAYYTNACNGARGARGCNAARGARMGNGTNYTNMGNGARCAYGAR CARAAYATGCARGCNYTNTCNAAYCARYTNYTNMGNAGYAARATGMGNCARCARAARAGY YTNGARYTNAARYTNACNCARMGNAARGCNMGNYTNGCNGARYTNAARCARCARAARGAR GARGCNYTNAGYCARMGNAARGARYTNAAYGARMGNGARMGNGARAAYYTNCARAARCAR ------YTNGAYGCNCARATHTCNCARGARGARCARAAYTTYGARGCNGCNMGNCARGCN GCNGTNGCNGAYYTNMGNMGNCARYTNGCNGARGARACN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GTNMGNATHATHGAYAARACNTCNMGNTTYYTNMGNACNGGN GCNCARGAYATHGTNYTNCARTGYGARATHAAYCARGGNATHGCNTTYYTNGTNAAYCAY AARGTNGARTGGATH------------MGNGCNTCNATGGTNGAYGGNAAYGTNCARGAR ACNGTNATHTCNGTNGGNGCNCARGTNCARCARGGNCAYCCNAAYTTYTAYGAYGTN--- CARTGGGARGTNATGGAYAARGAYGGNCCNATHYTNYTNAGYYTNACNATHAARMGNACN MGNGAYGARGAYGAYGGNTTYTAYATGTGYMGNGCNTCNCCNGGNCCNGTNGCNTCNGAY MGN------------------GTNAAYGTNACNATHGTNMGNGAYYTNGARTAYGTNACN ATGGTNTTYAARGGNAARCAYTAYAARTCNGGNGAYGARTCNAGYYTNCCNGTNGAR--- ------YTNGAYYTNGGNACNTAYCCNGTNACNTGYACNGCNGCNGGNTCNAAYCCNGCN ACNGARGAYGTNACNYTNCARATH---GGNTCNMGNCCNATHGARATHGCNAAYAARGAY ATHAARCARATGTCNTCNCCNTTYACNAARTAYGARACNACNGTNACNGCNGARGTNGAR ATHGGNCAYGGNGAYAGYGGNCAYTCNYTNAGYTGYACNGCNGCNCCNAAYACNCARGGN AGYATGACNATGAGYGCNAAYGTNGARGTNGAYGTNAAYGTNTAYGAYCCNGTNATHACN TGYYTNAARGCNYTNGCNACNAARGAYCARMGNTAYCCNAARYTNACNTGYTTYGTNGAY CAYTCNGAYGTNGARGTNAARGARTAYATGTTYGARATHGARGAYACNGARGARGTNATH MGNGARGGNCARACNCAYGAY---------GAYCAYATHYTNYTNTCNACNCARGCNGTN AAYGAYACNCAYACNGTNGTNGTNYTNGAYYTNTAYAARACNAARAARTGGCAYTTYGAY AGYAAYTAYTAYYTNGTNGTNGTNACNTCNGAYGAYMGNATHACNMGNGCNCCNGTNAAY YTNCAYMGN--------------------------------------------------- ---------GCNAGYATHACNATHACNTGYCCNGARAAYCAYGTNATHAGYYTNGARGAR GCNYTNTTYGGNMGNAAYGARTGGGGNGCNTGYTAYYTNACNAARAARGAYTGYACNGAR AARACNAARGTNTTYGAYCCNTGYGAYGGNYTNCARATGTGYAAYGGNGARYTNMGNMGN MGNGGNAGYCAYACNTCNACNCARAGYGAYCARYTNCCNTTYGCNGTNATHAAYMGNAGY GTNATGMGNMGNGAYTCNTTYGARATGCCNCARMGNACNATHATHGAYTCNCCNMGNCCN ACNMGNTCNMGNTCNYTNCAYAARACNCCNAGYGAYTCNCAYGTNCCNYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYGARYTNGCNMGNGAYTTYGCNGTNYTNMGN AARACNYTNYTNAARTAYCCNAGYTAYGCNGCNAGYTCNYTNTAYGGNCCNGAYGTNACN AAYYTNATHCAYTCN---AAYGCNMGNACNTAYYTNGAYGGNTTYYTNAARTCNGGNGGN GAYGARYTNGTNACNGCNGCNTGYGTNCAYCARTAYTAYYTNAAYGGNMGNATHGCNACN GTNGAYGAYTTYYTNAGYTCNGTNGTNYTNGAYAGYYTNMGNGGNGARYTNACNATGYTN GTNAAYATHAGYAGYTCNCARCCNGTNMGNYTNACNGARACNTCNTCNGCNTTYGGNGGN GGNGCNCCNGGNYTNTCNGAYGCNTAYGTNGCNGGNTTYYTNTGGYTNGAYAARYTNGGN YTNTCNGCNCARTAYGGNGTNCARGCNGTNTTYMGNCARACNTTYTAYGGNGGNAAYTAY GCNATGGTNTCNTCNGARYTNGARCCNTTYCCNGAYTAYTTYYTNACNYTNATHTAYAAR MGNYTNGTNGGNGGNCCNGTNTTYAAYATHACNACNACNCCNTCNTCNCCNGAYATGMGN GTNTAYGCNCAYTGYGCNAAYCCNCARAGYTAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GGNCARGAYATGMGNGGNCCNMGNCCNACNTTYGGN GGN------------------------------------------CCNGCNCCNGAYGGN TCNGCNCCNAARGAYATGGGNCCNMGNGGNATGGGNCCN---GGNGCNYTNCCNAGY--- ------CARACNCAR--------------------------------------------- AAYATHATGGAYCCNATGGARGAYCCNMGNTGGTCNGTNATGMGNGGNATHMGNGARGCN GAYGGNACNGARGARATHGTNATHGAYGGNAARCCNTTYGARYTNCAYATGGGNACNTCN MGNAARYTNYTNATGTAYGGNCARTCNATHGARGTNGCNGCNGAYGTNGTNGAYMGNGGN ATHMGNATHAAYGGNCARYTNGTNTAYAARYTNGGNGARCCNATHAARGARGTNCARGCN YTNGGNMGNGTNGTNAARYTNTAYTAYCAYGGNATGCCNMGNCCNATHTGGYTNGAYGGN CARCARCAYGARATGMGNYTNGAYGCNCCNCCNMGNAAYATHAAYGTNGAYGGNCAYMGN MGNGGNTTYCARATHGAYGGNMGNGAYATGATGATHYTNGTNGAYMGNYTNGARAARGGN CCNTAYGGNGGNCCNCCNMGNCARATHAARATHAAYGGNYTNCCNCAYGARATHAGYTTY GARGCNCCNCCNMGNMGNATHYTNATHGAYAGYAAYTCNTGYGARYTNAARYTNGAY--- AARATHCCNTAYGTNATHATHAARGGNAARCCNCAYGGNATHMGNTTYGAYGGNGARCCN MGNACNGTNTTYATHAAYGAYYTNCCNTTYACNGTNCCNATGGAYMGNGCNGTNAARATH AARATHGGNAAYMGNCCNACNTAYATHGCNTTYGGNGGNCCNTCNCAYGARYTNATHATH GAYGGNAARTGGTTYGARGTNAARTTYGAYAAYGARAAYAARGAYATHCAYYTNGGNAAY MGNCAYTTYGTNGTNMGNYTNCCNGGNGAYYTNCCNMGNGTNAARATHYTNGGNGARYTN CCNGCNGAYATGGGNGARTCNMGNYTNYTNATHGGNGAY--------------------- ---------------------------------GTNCCNAAYACNCCNGGNATGGCNMGN CAYCCNYTNGGNAAYCCNGGN---------------------------------CARTCN GGNCCNMGNGGNCCNATGTCNGGNTCNATGTCNGGNCARMGNATGCCNTTYCARCCNGGN GARGGNTCNCARCAR------------CCNGAYATGCARGCNYTNTCNGGNCARCCNCCN CARCARGGNTCNYTNAAYCARGGNATGCCNGGNCCNATGGGNATGCARGGNCARGCNYTN AAYCARGCNYTNCCNGGN------------CARATGGGNATGATGGGNCCNCCNGGNTCN GTNCARCARCARCARCARCCNCCNCARATGATGCARCARCARCARCCNCCNCARATGATG CAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TAY ACNTGYCAYGTNTGYGGNGARAARTTYAGYAAYGTNTCNTCNYTNGGNGGNCAYATGAAR ACNCAYGTNYTNGCNAARCCNTTYGCNTGYGAYATHTGYGGNCARMGNTTYACNCARAAR GGNTCNGTNGTNGTNCAYAARMGNATHCAYACNAAYGARAARMGNTTYTCNTGYAAYGTN TGYGGNTTYAARTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CARGARYTNYTNATHTCNGAYCCNAGYYTN GTNTCNTCNACNGAYGGNGAYYTNTAYACNCCNYTNCAYMGNGCNTCNTAYAAYAAYCAY CCNGAYATGGCNAARYTNYTNYTNTCNCAYGGNGCNAAYGTNAAYGCNMGNACNMGNGAY CARTGGTGYCCNYTNCAYAGYGCNGCNMGNTGGAAYTCNACNGARACNGCNCARGTNYTN ATHCAYAGYGGNGCNGGNGTNAAYGCNCARACNAAYGGNGGNYTNACNCCNYTNCAYYTN GCNGCNTCNGARMGNGARAAYAARGARGTNYTNGARYTNYTNYTNGCNGAYCCNTCNGTN GAYGTNACNYTNACNTCNAARATGGGNGARACNGCNMGNGAYATHTGYCARMGNTCNAGY GCNCAYTAYAAR---------------------------------------------CCN GTNMGNACNATGAARGARTAYGAYCARCARATHTCNGARYTNAARAARGARAAYTTYAGY YTNAARYTNMGNATHTAYTTYYTNGARGTNMGNAAYCARGARCARTAYGGN---GCNCAR GAYGTNTTYMGNACNAAYATHGARYTNAARGTNGARYTNGARACNYTNAARAARGARYTN TAYGAYAARCARGARYTNATHAARAARGCNGCNCARGCNATGGARGCNATGTCNGGNAAY CARMGNGARGARGARGARGCNGTNMGNGCNAARGTNGARGARGARCAYGCNCAYMGNATG GAYGCNYTNMGNAGYGAYYTNCARGAYGCNYTNGCNGAYGCNTCNGCNAGYMGNAARGAR YTNGARGARGTNAGYGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CARYTNAARGARGARAAYMGNCARATGAARGCNGCNYTNGCNGTNYTNACNGGN ACNYTNCCNAAYCARGGNGARAGYAGYACNGAYGCNATHGCNMGNYTNAAYGCNTCNYTN ACNGCNATGTCNGGNGTNCARTCNGAYYTNTCNAAYCARYTNGAYTCNYTNGGNACNGAR YTNAGYTCNCARATHGCNAAYATHTCNYTNGTNCCNGGNCCNCARGGNCCNATGGGNGCN GGNAAYYTNTCNCARTGYGTNATGAARTCNGCNATHAARATHTCNTCNTAYTCNTCNTCN TCNCCNGCNACNTCNGCNGTNYTNCCNAAYATHGARGAYTTYGARGAYTGGGTNCCNATG TCNGCNTAYTGYGTNTCNGAYAAYGCNGAYCAYGARCARATHAARTCNCARATHTCNTCN ACNCARTTYMGNTTYCARTGYCAYTGYGTNGGNYTNMGNTCNTCNGCNMGNATHMGNTGY GARATHTAYGTNTGGATGTGYCCNMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNCCNTAYYTNGGNAGY AARATHAGYYTNATHTCNAARGCNGARATHMGNTAYGARGGNATHYTNTAYGCNATHGAY CCNAAYGARGCNACNGTNGCNYTNGCNAARGTNMGNTCNTTYGGNACNGARGAYMGNCCN ACNGAYMGNCCNYTNCCNCCNMGNAAYGARGTNTTYGARTTYATHATHTTYMGNGGNCAY GAYATHAARGAYYTNCAYGTNTGYGARCCNCCNAARCCNCARCCNACNGAR---GGNGTN CCNCARGAYCCNGCNATHGTNAARTCNTCNCARCCNCCNCCNGGNCCNGCNGGNGCNGCN TTY---GGNGGNAGYGGNGCNGGNGGNTTYCCNCARGGNCARGGNTAYCARCCNTTYGGN ------------------------AGYCARCCNGGN---------GGNATGCCNTAYTAY TCNGGNCARCCNGGNGGN------------TTYCCNGGNATGCCNCCNGCNTCN------ ---------------------------GGNACNCARCCN---CCNGGNTCNGARAGYTCN ACNCCNCCNCCNAAYMGNAARTCNCCNACNTAYGAYCARAGYGTNCARACNATG---GGN GGNGTNGARMGNCAYMGNGGNGAYACNAGYGCNAARAGYCARTAYCCNCAYCAYAAYCAR CARCAYMGNCARCARGGN---------GCNATGAAYMGN--------------------- GGNGGNTAYMGNGARMGNATGGAYTAYMGNGAYCAYGGN---------GAYAAYMGN--- GARMGNGGNCCNTCNGCNACNTAYTCNMGNGGNMGNAGYAAYAAYMGNGGNCCNGCNCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATHGGNGTNATH TGYCCNTAYCARGARCARAARCARYTNATHYTNAAYAARYTNMGNCARGARCARATGGAY GGNGTNGGNGTNAAYACNGTNGAYAGYTTYCARGGNCARGARAARGARGTNATHATHATG TCNTGYGTNMGNGCNMGNAGYTCNACNGGNTCNATHGGNTTYYTNTCNGAYMGNCARMGN ATGAAYGTNGCNYTNACNMGNGCNMGNMGNGCNYTNTAYATHTGYGGNCAYYTNGAYACN YTNAARACNTGYACNCAYTGGMGNGARYTNATHGCNGAYGCNAARGARMGNMGNGTNGTN GTNCCNGTNGTNGAYTCNTGYGGNTTYAGYGCNGTNGCNGCNCARMGNTGY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GCNGGNATHGTNAARCCNGTNAARAARCCNYTNGGNAAYACNCARCCNTTYGTNCCN ACNGTNACNTCNACNACNAAYATHAAYTTYGAYTTYGCNAARTCNCCNACNAGYGGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNATGGARGARATGAAYGARGTNCAR ACNGGNMGNATHMGNYTNGAYGTNGGNGGNCAYAGYGTNMGNAARGARGARGAYGGNACN GTNTTYATHGAYMGNGAYGGNACNCAYTTYMGNTAYATHYTNAAYTAYYTNMGNGAYGGN GGNATHAAYCCNGAYTCNYTNCCNMGNAAYAARCARGTNYTNAARGARYTN--------- ------------------------------------------------------GTNGAY GARMGNATGGAYGTNGCNYTNTCNGAYAGYGARGCNTCNGAYGAYGAYGGNGARACNTGY YTNYTNGAYATHYTNGAYACNGCNGGNCARGARGARTAYTCNGCNYTNAARGAYCARTAY ACNTAYGAYGCNGAYGGNTTYTGYATHATHTAYAGYATHTCNGAYGCNAGYAGYTTYCAR GARGCNGARGCNATGTTYAGYTGGYTNAARMGNGTNMGNTCNGAYAARCCNTCNTAYTCN GTNYTNATHGCNAAYAARGTNGAYYTNTCNGGN---CCNGAYCARGARGTNTCNTCNCAR CARGGNAARGAYYTNGCNAGYMGNATGGGNGTNCCNTTYTTYGARACNTCNGCNAARYTN GGNCARGGNGTNMGNGARGCNATGGARGGNYTNGTNAARACNATHCCNMGNGARGGNATG GAYTAYAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNYTNTTYGGNACNATHTAYCCNGCNTAYGCNTCNTAYAARGCNGTNAAY TCNMGNAAYGCNAARGARTAYGTNAARTGGATGATGTAYTGGATHGTNTTYGCNYTNTTY YTNTGYGTNGARACNTTYTCNGAYGTNYTNYTNTCNTGGYTNCCNTTYTAYTAYGARATH AARATHGTNTTYGTNATHTGGATGYTNTCNCCNATGACNAARGGNTCNAGYTTYYTNTTY AARAARTTYGTNCAYCCNCARYTNAARMGNMGNGARAARGARATHGAYGARATGATHGCN CARGCNAGYMGNCARGGNTAYAGYACNYTNYTNACNYTNGGNACNAARGGNYTNTCNTAY GCNTCNCARGTNGTNATG------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CCNGAYYTNTCNTCNCCNGCNGTNCCNCCNGCNTCNMGN---GCNGCNGCNTCNTTY TCNGGNAARCCNTCNTCNTCNTAYGGNGGNTTYATHAAYGCNGCNACNTCNGGNCAYAAY MGNTCNCARAGYYTNACNYTNGGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNGGNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGTCNTTYTCNGTNGTNGARAARAGYTTYGCNYTNTTY------GCNGARCCNACNCAY GTNGCNTCNCAYTCNAARMGNAARCARTGYAARAARACNAAYGAYGGNATGAARYTNATH AAYACNGAYAARAARGGNGTNTGGMGNGARYTNMGNMGNYTNCAYTCNCARAARMGNAAR GCNGTNGCNGARAARMGNTCNMGNAARCCNCARGTNTCNGCNYTNGARGCNTAYTGYGCN GARAAYAGYGTNGAYCAYACNGARGARAAYGTNGCNGCNYTNGCNMGNYTNGGNGARATG ACNAARGTNAGYCCNGAYGTNGTNCARAARGTNMGNTGYGTNTCNCCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TGGMGNGARCARMGNCARTTYYTNGAYYTNGCNYTNYTNGCNYTNGAYGAYCAYCCNYTN TCNAARATGGTNAARGCNGARTAYGGNCARYTNAARCCNAARCARCCNGAYATHACNGGN TAYTCNAARGCNGARYTNGGNAARGAYTAYAARTGYTCNGAYGGNGTNGTNYTNAAYTTY GGNAARGAYGGNTCNYTNMGNMGNYTNTAYGAYCCNTAYAAYAAYMGNGAYTGGGCNGCN GAYAARTAYCCNATHGGNCARYTNACNTAYGAYACNTTYGAYGARGCNCARTTYAARGAR ATGGCNAARYTNTAYAAYTAYGARGCNGGNGTNGGNTTYGAYAARCCNAAYGTNACNCAR AAYGCNCAYCCNGARMGNAARMGNTGG--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GTNGGNATGYTN GCNGAYCCNGCNAARATHGCNAARGARMGNGARAARGARGARMGNGTNMGNYTNGCNMGN GARMGNYTNGCNGARGARMGNAARAARAARYTNGARGARYTNAARGARCARCARMGNATH GCNGARGARAAYMGNAAYMGNATGYTNCARCARMGNAARCARAARATHGARGAYYTNMGN MGNMGNGAYATHGARMGNMGNGCNGCNGTNGARGARMGNMGNAARCARAARGARGARGCN GARMGNGCNMGNMGNGARTCNATHYTNGCNAARGCNGARGARMGNGTNGCNMGNTAYGAR GCNTGGAARGCNGGNGGNMGNAARGGNGGNYTNGGNTTYGGNAGYGGNACNCCNMGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNCARGTNYTNGARAGYMGNTCNCCNTGGMGN YTNTCNTTYATHCCNGARATGTTYTGGGGNTTYATHAAYTTYATHGTNYTNTTYTTYGAR ACNATGTTYAAYCCNAAYAARACNMGNCARGGNAGYGGNTAYTCNACNGAYTAYMGNMGN CCNGGNGGNGGNGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AARMGNYTNYTN GCNAARGGNGGNCARGGNYTNCCNGARATHGTNGARGAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNTCNTAYGCNGAYYTNATHACNAARGCNATHCARAGY TCNCCNGARAARMGNYTNACNYTNTCNCARATHTAYGAYTGGATGGTNCARAAYGTNCCN TAYTTYAARGAYAARGGNGAYAGYACNAGYTCNGCNGGNTGGAARAAYTCNATHMGNCAY AAYYTNTCNYTNCAYAGYMGNTTYATGMGNATHCARAAYGARGGNACNGGNAARAGYTCN TGGTGGGTNATHAAYCCNGAYGCNAARCCNGGNAARACNCCNMGNMGNMGNGCNGGNAGY ATGGARACNAARAGYTAYGARAARAARMGNGGNMGNATHMGNAARAARATHGARYTNMGN AAYGCNYTNGARAAYGGNGGNACNCCNTCNCCNGGNGCNACNGARGAYTAYYTNGAYGGN TAYGGNGAYTTYMGNTCNMGNGCNAGYTCNAAYGCNAGYAGYTGYGGNMGNYTNTCNCCN ATHCAYGCNATGGCNGARCCNGAYYTNCAYGAYAAYCARGTNCCNCCNATGTCNCCNATH CCNTGGGGNTCNGARGTNGARGGNTCNCCNACNYTNTAYGGNGGNGAYAAYTAYTCNGAR YTNGTNGARTCNYTNGTNGAYAGYATGAARYTNTCNAGYCARGARGGNATGGAYYTNGGN TCNAGYYTNCARGAYCCNTAYYTNTCNGGNTCNCARCARGAYTTYAAYAGYCCNCARCCN AAYTTYYTN------------------------------------------TCNGARACN CCNATHGTNAAYGARATHGAYCCNGAYMGNYTNAAYATHGTNAARCARACNAAYATGTCN CARCAYGTNGCNGTNCARATGGGNTGYGCNCAYCCNCAYTTYGAYGAYMGNGGNTCNATG TAYACNTAYGGNACNACNTTYGAYTGYTAYAARGCNTAYAAYATHATHGARATHCCNCCN CCNGCNGTNGGNAGYGAYATGATHTCNAARGCNMGNATHATHGCNACNGTNCCNTCNMGN TGGGCNGTNAAYATHGGNTAYAAYCAYAGYTTYGGNATGACNGAYMGNTAYTTYGTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARGGNYTNYTNTTYCARAAYCAYYTNCAYGGNMGN CCNYTNGTNGAYGCNACNATHCAYACNYTNGTNGTNATHGTNGTNTAYGCNTCNGCNATH GTNGTNATHGCNGARGCNAARTTYAARTTYYTNACNACNYTNCARGGNTCNTGGTTYTGY GCNGTNGGNATHATHYTNTAYAGYCCNACNGGNAGYAARTGGGAYYTNACNAGYCAYGAR AAYAGYATGYTNTCNGTNATHTAYTTYTCNTGGCAYGCNGCNATHATHYTNGTNYTNGTN YTNATGGCNGGNATGTCNYTNTTYTAYMGNGGNGCNGGNACNACNGCNTAYGARACNACN ACNGARMGNCARGCNGGNCCNGCNCCNATHMGNCCNGAYCCNGGNTAYGCNAARTCNYTN CCNGGNYTNYTNAARATHACNGARATHGTNYTNTGYGTNYTNGCNYTNATHTGYAGYTCN ATHGAYTAYTGGTAYCAYYTNGGNGGNGGNTGGGTNCARTTYGTNGCNGCNTCNGCNATG ATHACNACNATHGTNYTNTTYATHYTNCAYYTNTTYCAYGTNATHTCNMGNYTNCCNGGN CCNTGGYTNTTYATHGARTTYYTNTAYTAYGTNGTNTAYTGYGTNYTNTTYGTNATHGCN GCNATHGTNTGYGCNGTNMGNGCNAAYMGNGCNCCNTCNATHGGNGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AAYAARTTY ATHCCNAARAARCARYTNGARGCNGAYAARMGNCARGTNGGNYTNGAYACNAGYATHGCN CCNAAYAAYAARGGNTTYGCNYTNYTNCARAARATGGGNTAYAARCCNGGNATGGGNATH GGNAARGARGGNTCNGGNMGNAARGARCCNGTNCCNATHGARGTNAARATGGGNMGNAGY GGNYTNGGNMGNGARTCNGARATGAARMGNAARGCNTCNGARATGAAYATGATGMGNGCN GCNATGTCNGCNAARMGNCARAARAARATGGARCAYCARAARTCNCARTTYATGTCNMGN ATGAGYGARMGNTTYACNGTNMGNAAYGCNGARMGNGAYYTNAARATHGCNCARAARGCN TGYATHCARYTNGAYCAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TAYCARACNGCNYTNGAYYTNYTNYTN TGYGCNTGYTCNGTNATHYTNATGTTYCCNAARTCNTCNCCNYTNGGNYTNMGNMGNAAY YTNTCNTTYCARGTNGGNMGNGGNGCNAGYAAYGGNGARGCNAARGTNMGNGCNGGNTCN AGYTAYGCNAAYGGNYTNGAYGCNYTNMGNAARTAYYTNCARGCNTCNGAYTTYYTNCAR AAYGTNGTNTAYATHAAYYTNCCNYTNCARGARGAYGAYMGNATHCARMGNTAYAAYACN YTNGCNTCNYTNTAYACNCARATHGGNTTYCAYMGNAARGCNGCNTTYTTYAARMGNGTN TCNGGNATGYTNTGYGTNGCNCCNGAYAGYTCNCCNTCNTGGCARCAYTGYTAYCARYTN YTNYTNCAYTGYYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYGAYTGYCCNATHTGYATGTTYCCNCCNATHAAR CCNTTYGCNYTN---MGNTGYGGNCAYGTNTTYTGYACNYTNTGYATHCARAARGCNYTN AARTGYCCNGTNTGYMGNTCNCCNTGYGGNAARATHACNGGNAAYATGCCNGAYGGNAGY ATGTCNGTNTCNACNTCNAGYAAYGAYGTNGARGGNTAYAARAAR---TGYGGNAGYYTN GARATHGGNTAYYTNTTYYTNGAYGGNACNCARGGNAARGARCAYGARAAYCCNGGNGAR MGNTAY------AARGGNATHAAYMGNAARGCNTAYYTNCCNGAYGARGGNMGNMGNGTN YTNGCNCAYYTNMGNGTNGCNTTYAARMGNMGNYTNACNTTYACNATHGGNACNTCNAAY ACNACNGGNGTNAARAAYGTNATGGTNTGGAAY---ATHCAYCAYAARACNAARMGNGAY GGNGGNGARAARCAYGGNTAYCCNGAYGGNACNTAYYTNCARMGNGTNATGGARGARYTN GARCARAAYGGNGTNACNGARGAYTCNTTYTCNGAYGAYGARMGNMGNGAYGTNGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GTNCARCCN ATHCCNGGNGAYTCNGAYAARCCNMGNTAYAARGTNTGYGTNGCNGCNMGNAARGAYGTN CCNMGNTTYTCNCCNTTYYTNTCNTCNTCNGCNGARTTYACNCARGGNGARGARTTYMGN GARTTYYTNYTNACNAARYTNATHAAYGCNGARYTNGCNTGYTAYAARGCNGAYCARTTY GCNAARYTNACNYTNGCNGAYGTNGARTCNAARTGGAAYGAYYTNACNGARYTNYTNGTN CARCARGTNTCNYTNGARGCNYTNTCNGARATHGAYGGNATGYTNAARYTNAARAGYAAR MGNAAYGCNGTNAARGAYATHATHGAYAARTGYACNMGNATGYTNMGNGARACNGCNAAY TCNCARACNGAYGARATHAARTCNMGNYTNGAYAGYATHMGNAGYCARGCNGAYGTNGTN TGYCAYATGAGYGCNGARMGNYTNCARCARYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------MGNAAYAGYMGNTCNGGNGAYGARAAYGTNCCNCCNGARTCN MGNGARAARCCN---GAY---TCNGGNTTYMGNAAYMGNGAYAARGGNGARMGNGAYGGN GGNTTYGGNGGNGARAARAGYMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNGGNMGNGGN GGNTCNMGNGGNGGNAGYGCNGGN---GGNGARMGNGGNGGNTTYGGN------GGNGAY MGNAARMGNGARTTYGAYMGNCAYAGYGGNAAYGAYMGNACNGGNATHAARCCNATGGAR AARMGNGARGGNGGNGGNGCNCAYAAYTGGGGNACNTAYMGNGAYGAYYTNGARNNNNNN CCNCAYGCNGAR---------GARAARGAYGARTGGGGNTCNCCNGGNAGYGAYGGNGCN GAYGTNGCNAAYGGNACNGAYACNGAYGAYCCNGARGCNGCNACNCCNGCNAGYCARGAR CCNCARGTNATGACNYTNGAYGARTGGAARGCNYTNCARGGN---CARGCNAARCCNAAR CCNGARTTYAAYATHMGNAARGCNGGNGARGGNTGYGAYAGYAAYCARTGGAARGARACN ACNYTNYTNAARAARAARGCNGARGAYGAYAGYGARGARGARAGYGARGARGARGAYGAY GAYGARGAYGARGARGAYGARCARATGMGN---CARAARAARYTNYTNACNGAYATHMGN ATHACNTTYAAYGAYAAYCCNMGNMGNGGNMGNGGNGGNMGNMGNGGNGGNGGNGGN--- ------MGNGGNGGNACNCCNGGNMGNGGNGGNMGNGGNTTYGGNGGNMGN------GGN GGNCARMGNGGN---GGNTAYGGNCCNMGNGARGCNGCNCCNMGNTTYGAYGAYGARAAY GAYTTYCCNTCNYTNGTNAARTCNGARGCN------------------------------ ------------------------------------------------------------ ------------------------------------GTNGGNGTNAAYYTNGAYAAYGTN TGGAGYATHAARAAYGTNGGNYTN---------------------MGNTCNGAYYTNACN TCNTCNAGYTCNGAYAGYYTNACNAARAAYGCNTCNAARGCNTTYTAYTCNMGNCAYGGN GGNATGAARGGNGGNYTNAARAAYAAYMGNGGNGAYACNACNYTNACNTCNGCNGCNTCN TCNGAYGTNGGNCARAARTGGACNAGY---------------------CARTCNAGYMGN AGYCARGCNTAYAGYTTYGCNCARGGNTCNAARTCNGARYTNATGGTNCCNMGN------ ------------------------------------------------------AARTGY TTYGTNATHGGNATHAGYGGNACNACNAAYAGYGGNAARTCNACNATHACNACNAARATH AARAARGCNYTNCCNGCNTGYGAYGCNATHAAYCARGAYGAYTAYTTYGTNGCNCCNGAY GAYCCNMGNYTNTAYATHCCNGARGTNAAYCAYCAYAAYTGGGARAARYTNAGYGCNYTN GAYATGGAYGCNATGYTNMGNGAYGTNCARGCNTGGATHGCNTCNCAYTCNACNAAYCAR ATGCCN------GTNYTNYTN---ATHGARGGNTTYYTNATHTTYAAYAAYAGYGAYYTN AGYAARYTNTTYCAYMGNAARTAYTTYTTYGARATHGGNAARGARACNTGYATHGARMGN MGNAAYACNMGNACNTAYAAYCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GAYGAYGARGAYGAYGCNGCNTAYAGYCCN CCNTCNAAYAARCCNCCNGCNAAYGCNYTNTAYACNGTNCARGCNACNCAYACNTAYACN GGNGARGAYGTNGAYGARYTNAGYTTYGARCCNGGNGARATHATHCAYGTNATHAARTTY GARAAYGARGAYGARCARGAYGAYGGNTGGCARATGGGNGTNAARCARTCNGAYGGNTCN AARGGNGTNTTYCCNGARAAYTTYACNCARAARYTNGGNCCNGCNTGGATHTTYGCNYTN YTNGCNATHATHGCNATHATHATHYTNGTNATHATHTTYGTNATHMGNMGNMGNMGNAAR AARCARGARMGNTAYTCNGAYATGGCNGGNYTNCCNCCNCCNCARGCNGTNTTYAGYACN GGNAAYGAYAAYYTNGCNTTYACNAAYGARATGTAYAAYAAYGTNAAYMGNAAYGCNAAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNYTNMGNGTNGTNGTNCAYACNGCNAAY YTNATHTCNAAYGAYTGGTCNCARAARACNCARGGNATGTGGGTNAGYCCNGTNTTYCCN MGNYTN---AGYTCN---GGNTCNTCNGGNGAYTCNCCNACNGGNTTYAARTCNGAYYTN YTNGCNTAYYTNGCNGCNTAYMGNGTNGCNAARYTNGCNCCNTGGGARMGNCAYATHCAR GCNCAYGAYATGTCNAGYGCNMGNGTNTGYYTNATHTCNTCNGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AGYATHAAYTAYGGNATGTGGGARTTYTGY--- TCNAARTCNCCNTTYYTNTCNCARTGYACNAARTTYTCNGAYATGGARAAYTTYAGYTCN TTY---------------GARCCNGCNTGGYTNAARGCNGTNAARGCNATGGCNATHATH GGNATGYTNGTNGCNGGNAGYGCNGGNGTNGCNGCNGCNGTNACNGTNATHGAYTCNATH AARGGNCCNYTNACNMGNTTYYTNGCNYTNYTNGTNTGYGCNYTNTGYATGTCNGCNGCN GTNTTYATHGTNATHGGNGAYATHGTNGTNGCNAGYAARATGAARTCNYTNTTYGTNCCN YTNGCNYTNAGYCARGGNGGNCCNGCNATGAARAARTCNATHGARGAYAGYTGYTTYYTN GAYTGGGGNTTYATHYTNGAYATHGTNGCNGTNGTNYTNYTNATHTCNTCNGGNATHATH TAYGTNGTNTCNGGNMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AGYGGNGCNGGN TCNYTNAARCCNACNGAYCARAARTCNGGNGTNATGGTNTCNCCNAARGARGAYTAYAAR ATHMGNMGNCARAAYMGNAGYAARACNYTNCCNGGNGCNAGYGAYGAR------CARTAY TCNCCNAARATHCARMGNGCNAGYTCNCAYMGNATHTCNCCNGTNTCNGCNGTNGTNTCN ------------GCNAGYACNAAYGTNGCNGCNTCNAGYCCNGTNGGNAARYTNGAYGCN AARMGNTGGCCNTCNTCNGAYCCNGCNAARACNTCNGARCCNGCNTGGGTNAGYYTNGCN MGNAARAARCARGCNGARMGNTCNGAYAGYYTNGARGAYGCN---------TCNCCNGAY GGNAGYAARTCNGTNTCNTCNACNCCNATHGCNAGYAGY--------------------- ---------------------------------------TTYGAYAARAARMGNGGNAGY ATHGAYACN------------------------------GAYAARAARMGNGGNGAYAGY AGYAAYAARAAR------TCNGAYACNCCNGGNTCNTCNAARMGNGARAGYATHGARATH GAYATHTCNGARYTNATHAARGAYTCNGGNACNGCNCAYGGNMGNTTYCARTCNTCNGGN ACNAAYAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTNGAYGCNCARACNMGNCAR GCNGTNGTNGAYYTNGTNAAYTCNACNTGGCARGGN---CCNGTNGGNMGNGGNMGNGAY GCNMGNGGNYTNGTNCAYAGY---ACNATHGAYGTNGTNGAYGTNAARMGNGTNCARAAY AGYGGNYTNTTYGARAGYTAYGGNATGMGNMGNGCNCARYTNTTYMGNAARGCNGCNATG TTYGGNAAYTTYTGYGARAGYATHGAYAGYATHCCN---CARTCNACNGGNCCNGTNYTN ACNACNGTNAAYGCNGGNGAYYTNYTNAARMGNGARYTNTAYCAYACNGARATHAAYGAR CAYTAYYTNTTYCAYGGNACNAARMGNMGNGCNGTNMGNAAYYTNNNNGARTCNGGNTTY GAYTTYTCNYTNNNNMGNNNNNNNAAYNNNNNNGGNCCNGGNATHNNNGGNGCNGARAGY TCNGCNMGNGCNGAYCARGAYGTNGCNGGNTGYGAYGAYCCNATHTCNGGN------AAR AARACNATGATHYTNATGMGNGTNYTNYTNGGNCAYGTNTAYYTNTGYGCNGAY------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TCNGAYYTNCCNAAYGTNCARMGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGNATGTCNGCNATHTTYCARGAYATHYTNGTNGAY AARGTNYTNYTNAARGCNGTNCAYGCNAGYMGNYTNGTNYTNMGNGCNAARATGTGGGAR GAYGARTAYACNGARTGYAARYTNGARYTNGCNAARMGNAARAAYGCNMGNGGNAARYTN AARGAYTAYGARAAYGAYYTNAARATGGTNYTNMGNGTNMGNGARTAYCARAARGGNYTN GTNGARGARATHCARMGNYTNMGNGAYGCNGARAGYCARTTYGAYCAYCAYYTNGGNAAY TTYATGYTNTCNGTNAARAARATHYTNCCNAAYAAYGCNACNGCNATHMGNAAYGTNAAR GARTTYATHGCNAGYATHMGNATGGCNAARGGNGCNAARGCNTCNGAYATGAARGARATH GAYCAYTTYYTNCAYACNYTNGAYTAYYTNMGNAARYTNTAYCARCARYTNGARCARAAY ATHTCNCAYCCNYTNAGYCARGTNMGNGCNYTNGTNGARAAYGAYAARCARMGNGCNTCN AARGCNMGNATHAARCARATGTGYMGNGAYATGCARGCNAAYYTNMGNYTNGAYGCNGAY YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------GGNATHTCNACNCCNAGYGGNATH CCNGAYTTYMGNACNCCNGGNACNGGNYTNTAYGAYAAYYTNCARCARTAYAAYATHCCN TAYCCNGARGCNATHTTYGAYATHGAYTTYTTYCAYCAYAAYCCNMGNCCNTTYTTYGCN YTNGCNAARGARYTNTAYCCNTCNGGNAARTAYMGNCCNAAYTAYYTNCAYTAYTTYGCN MGNYTNYTNAAYGAYMGNGGNGTNYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GGNAARTCNGTNGCNGARYTNACNGAYTTYTGYAAR AARATHTCNCARAARGAYGARCAYGARGGNGTNAGYGAYAGYAGYGAYGAYAAYATHGAR MGN---CAYCARAGYGARGAYGAYGARACNYTNGTNCAYCAYCCNTTYAARATHACN--- CCNGCNTCNAAYATHGTNATGAAYATHMGNAAYGCNMGNCARYTNCCNGTNYTNACNCCN CARGARAARCARACNCARCARGCNCARYTNMGNATHGCNTAYCCNGTNTCNAGYGGNTCN CARCAYMGNGCNAAYGARTCNGARTGGGTNCCNGTNGARAARACNACNGCNCCNYTNGCN CCNACNACNACNACNGCNCCNGTNGCNAGYMGNCCNACNCCNGARCCNAARGCNGCNGAR CCNGTNAARTCNACNGARAGYATHTTYCCNGARCARAARGGNMGNYTNGAYATHAGYACN ATHGTNTCNGARMGNYTNCARGCNGTNMGNAARYTNCARGARAAYCCNTTYGAYGTNCAR GCNYTNTCNTCNATGCAYAARGTNTCNGARAARGCNAGYMGNTGGGCNCARTCNCARCAY YTNCCNGGNCARTTYACNGGNAGYACNGGNGTNAAYGTNYTNACNCCNGARCARYTNGCN GGNGAYAARMGNAAYCARGCNTGGTTYAARAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNAARGCNTTYCCNGCNTCNGCNGAYCARCCNGAYYTNATGAARGTN YTNMGNATHTCNTGGTCNGARAARATGMGNTCNGTNMGNMGNGCNGARAARMGNGAYGAR GARTTYATGAARGAYACNTTYMGNCARGTNTTYATGGARTCNGTNTAYCCNYTNGCNCAY YTNGCNGTNATGCCNGCNTTYMGNATGGGNGAYYTNGAYAAYGARACNGARMGNTCNGAR CAYGTNAARCARTTYTCNGARGCNAARCARGARGGNMGNGGNGCNYTNGCNGCNYTNYTN TCNCCN------------------------------------------------------ ------------------------------YTNGTNACNCARGCNGARGARYTNGGNTGY GARGGNAARGTNGARGARTCNCARGGNGTNATGAARYTNGTNGAYCARYTNAARGARGAR MGNCAYCARYTNGAR------AAY---CCNTCNGGNGARGAR---ATHCCNATGATGAAR CARATGGARGTNTGYGAYGTNTGYGGNGCNTTYYTNATHGTNGGNGAYGCNCCNCARMGN CARGAYGARCAYYTNATGGGNAARCARCAYGCNGGNTAYGCNCARGTNMGNTCNGARATH GARAARMGNMGNAAYAARMGNAARCARGARYTNGARGCNMGNGARGCNAAYGARGCNMGN YTNGTNAARGARMGNGARGARMGNGARAARGCNMGNGARAARGARAARGARGARMGNMGN MGNMGNGARAARGARMGNGARMGNGARAARGARAARGARAARGARMGNGARMGNMGNMGN MGNAGYMGNTCNMGN------------GAYMGN---------------------MGNMGN MGNTCNMGNAGYMGNAGYMGNGAYMGNMGNGGNMGNMGNAGYMGNAGYMGNAGYMGNGAY MGNAARMGNMGNTCNMGNAGYGGNAGYMGNAGYGGNMGNAGYMGNMGNTCNTCNAGYMGN GARAARAAYTCNAGYGCNMGNMGN------------------------------MGNTCN MGNGAYMGNGAYMGNMGNTCNMGNTCNMGNGAYMGNAARGAYAARMGNAGYMGNGARAAR GAYMGNGARMGNAGYMGNGAYAARGAYMGNGAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AAYTTY YTNCAYGAYGAYCAYGGNTCNCARTCNGAYGTNGAYMGNAARCCNGCNATHGARCCNGAY ATHAGYATHGTNAARGARGARTAYATGCARGGN------TCNTCNTCNGGNTAYGGNGGN GAYAGYMGNTCNACN---------------------ATGCCNTCNTCNAAYAAYTAYCCN GTNATGYTNCAYCARTCNTCNAGYTTYCCNCAYAGYCARTCNGGNTTYAAYCCNCAYTCN CARCARCCNTCNGGNGCNTCN---------CCNGAYTTYGCNGGNATGGGNGGNGCNMGN GAYGARGARYTNGARATGTAYTAYMGNAARGGNACNGAYCARCAYYTNATHTTYYTNMGN AAYATGMGNGARGCNCAYGCNATGTAYCCNTTYACNGGNAARMGNGAYAARGARYTNTTY GAYAAYGCNYTNGCNGARYTNTAYMGNMGNYTNCCNATHYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATHCARACNTAYGTNCCNTGGAAYGTN CAYGARATHACNCCNGGNCARTTYGTNTTYGAYGGNGGNTCNGAYYTNGGNGCNTTYYTN AARCARGCNMGNGAYYTNGAYYTNYTNGTNYTNYTNMGNATHGGNCCNTAYATHTGYGGN GARTGGGARTTYGGNGGNTTYCCNGCNTGGYTNYTNACN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARGARAARAARGARAARGARAARGAR ------CARMGNCARAARGARAARGCNGAR---------AARGARAARCARGCNGTNTCN ---------------AARGARGTNGTNGARGARGARGAYGARGGNAARATHYTNCAYATG GAYACNAAYGAYTTYGCNTTYGGNGARGGNYTNGTNTGYGTNGTNTGYMGNCARTTYGAY GTNATHTCNGGNAAYAARYTNGTNGARTGYGGNGARTGYCARGAYYTNTAYCAYCARGAR TGYCAYAARCCNCCNGTNACN---GAYGAYGTNGAYGAYCCNMGNTTYGTNTGGTAYTGY TCNAARTGYTCNAARACNCARAARAARATGATHTCNCARAARTCNCAYAARTCNCCN--- TCNCCNGCNGTN---ATGTCNTCNGCNTCNAARGARACNAGYGCNCCNGTN---AARCCN ACNAARYTNGAYACNGAYTCNTCNTCNCARCCNTTYAARMGNGTNGAYGCNAARGGNAAR GAYAGYMGNTCNTCNTCNCCNTCNTCNTCNTCNTCNGCNAARCCNYTNGGNGGNYTNGCN AGYYTNGCNGTN---------------------AARGCNAARGCNGARAARTCNTCN--- ------------AARAGYGAYGGNTCNAARTCNTCNAARTCN---------------YTN AARTCNGAYCCNACNAARAARTCNGARGCNGARAARGCNGARGTNYTNAARGCNYTNTCN GCNAARAARGGNGAYGGNGAYAAR------------GGNAARAARTCNGARTCNGAYAAR GGNGARGCN---TCNCARAARAGYGGNTCNTCNAARTCNGAYAGYGTNMGNAARAGYGAY TCNGARMGNTCNGARTCNCCNMGNAGY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CCNCCNAARATHACNMGNGCNCCNAARGAYAARAARGTNACNGAR GAYGGNACNGTNAGYTTYATHTGYMGNGCNTCNGGNAAYCCNGCNCCNTCNTTYCAYTGG GARAARTCNGGNAARMGNATHAAYTCNMGNMGNAAYMGNTAYGAYATHGTNGAYGTNGCN CAYATHTCNGTNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGGCNCARAAYATHCAYCAY GARGCNMGNMGNAARCARATGTTYATGGAYMGNGTNTGYGCNGCNMGNAARGARTAYGGN ATGGGNGCNGAYGCNGTNGTNATGCCNAGYGGNGGNACNAARATGTGYCCNAARACNGAR ACNATHATGAGYACNGAYCCNGGNCARTTY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARAARGCNTGYTCNGGNYTNMGN AAYGAYYTNAARYTNTGYYTNYTNGARAGYGAYTGYTGYMGNAARGARMGNAARACNCCN MGNGARTGYYTNGGNCCN---AAY---------GAYCCNTCNATHTCNCCNGARTGYCAY MGNYTNMGNCARGCNTTYTTYGARTGYAARMGNTCNYTNGTNGAYATGMGNGCNMGNTTY MGNGGNATHAARGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARGARMGNAAYTCNAARAAYGCNAARCARGCNAARATHAAYMGNGARAARAARAARGCN TAYGTNAARGGNYTNGARGAYGAYATHATGMGNATHACNAARGARAAYTGYGAYYTNMGN AARGARAAYGARTCNATHAARAGYGARAAYCARGARYTNGARTCNGARYTNGARTAYYTN AARGCNGTNYTNGCNAAYCARAGYACNYTNTCNAGYYTNYTNAARAAYATHGGNAAYGTN AARGAYATHACNYTNTCNTCNTCNTTY---GGNCARAARMGN------TCNGTNGAYGAY GAYCAYTGYTAYGGNGCNCCNGAYACN------AARMGNMGNMGNCARAGYCCNGCNAGY TCNAARAARACNGGNGGNGTNTGYYTNCAYGTNAAYGGNTCNMGNGCNTCNYTNGARTTY TGYGCNAGYTGYGCNAARTTYGCNAARATHTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNACNGARGAYCAYCCNGAYACNCARATHGARTTY GCNMGNMGNMGNYTNCARYTNGCNCARAGYYTNTAYTAYAARATHYTNGAYAGYATHYTN MGNGGNGARMGNAARMGNYTNGARGGNAARGARGTNGAYYTNTCNGCNYTNYTNGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GTN ACNYTNGGNTGYGGNGARCAYYTNATGCARACNYTNYTNGCNAARACNTCNGCNGAYGCN GTNMGNTGYGCNGAYGAYGTNACNAARGCNYTNTGGTCNTCNTTYGARCARGAYTTYATG GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARGGNGCNATHAARGGNCARATHYTNTAYYTNGGNYTNTTYGARGCNGAYTTYGAY TGGAAYAAYGCNACNAARMGNGARCARMGNYTNAARTCNAGYGGNCCNTAYGGNMGNTAY CAYAGYCARACNTAYACNAAYGGNACNYTNTGYGAYYTNACNGGNCARCCNMGNMGNGCN GARGTNMGNTTYGTNTGYGARAARAAYAGYGARGAYCAYYTNATGMGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATHAARATHGCNGTNTGYGGNGCNTCNGGNTTYATHTTY GGNATHGCNYTNGARAARGGNMGNGTNTTYGARCCNGARGTNATHMGNGAYCARATGYTN TTYACNMGNTTYACNATGATGAARATGTTYYTNTCNGCNTCNGCNGCNGCNATG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GARATGGARMGNGTNAARGCNGARYTN GARGGNGTNAARACNGCNGCNGARGTNTCNGARMGNAGYAARCARGAYGARATHAGYACN YTNGTNCARAAYTAYAAYCARGARGTNGCNAGYYTNCARCARYTNYTNAARGARGCNGCN GARACNGCNTCNGAYAAYATHGCNGTNCARTTYGARTCNGARMGNAAYAARYTNGTNTCN YTNAAYGARAAYTAYGARGARGARATHCARGARYTNMGNAGYAARYTNAAYCARGCNMGN GARGGNTTYYTNTCNTCNGTNGCNAARTCNATHAARMGNGTNGGNGGNGTNGCNTCNAGY TCNATGGARATGTAYGTNGCNGTNYTNAGYACNCARAARACNGTNGTNCARGAYGAYTAY GAYMGNYTNCAYACNGARYTNCARGAYGTNTGYMGNYTNYTNGARGARGARAARCARACN CAYGAYTCNYTNAARCARACNTGGCARATGGCNAAYGAYCARTTYYTNGARTCNCARMGN YTNATGATGATGGAYATGMGNMGNATGGARAGYGTNYTNACNCARGARCARCARMGNCAR ATHGCNGAR---CARCAYAARGAYGARGARMGNGARGCNCARCARAARAARGTNMGNGAR YTNGARGTNGCNMGNCARAARAAYGARGARMGNMGNAARYTNAGYGARTCNMGNATGGAR AARGARMGNCARCARYTNAARCARCCNGAYCCNYTNGAYYTNGAYAARTCNGAYGCNGAY GCNACNACNACNGGNACNGAYGARGARATHGGNGCNTTYAGYACNGCNACNGARMGNGAY AGYCCNYTNYTNGAYAGYGGNGTNCAYGARACNMGNTCNYTNGGNACNGGNGGNAAYYTN ACNTTYMGNATHAGYCCNGARAARGTNCCNAGYYTNTCNGCNGCNCARYTNAARGCNATH ACNGAYCCNACNCCNGARACNGARGCNCAYAARTCNYTNGTNGAYMGNATHAARMGNCCN GAYAARATGCCNAARCARMGNCARTAYCARCARGARYTNGARGARTCNYTNAARACNTCN GCNGARGARGCNAAYATHMGNATHTCNAGYYTNACNAGYAARYTNGARGARAAYGARMGN TAYATGGARGARYTNAARCARCARYTNACNGTNGCNCARATHCARYTNCARGAYCAYGCN AARTCNYTNATHGARAAYMGNGARGARATHCARCAYGARYTNACNAARYTNCARGARGAR AAYGAYAGYYTNGTNGGNAARTAYTCNAARACNGCNCARCARYTNCARAAYGARGAYATH AAYYTNCCNAAYAAYYTNGARGARATGCARYTNYTNYTNYTNAARTAYMGNGARGARATH ATHTCNGCNAARGTNGCNAARGARCAYTCNGARGARACNYTNMGNAGYGARATHGCNTTY YTNAARTCNCARGCNYTNGGNGAYCARCARGARAARGCNACNATGGARGARGCNYTNACN CARGARATHTCNGCNYTNCARGCNAARYTNGGNAARYTNTCNMGNGTNCARGARGARTAY GARACNGARGCNMGNGTNMGNGTNGARACNGARACNAARYTNMGNGARGCNGARACNTCN YTNAARTCNATHCARGGNAARTCNAARCARYTNATHTCNAARYTNCARGARMGNYTNGAR GARGGNGARAARATHMGNTCNAARYTNGARGGNGARYTNCAYTCNYTNAARGGNAARGTN CARTCNYTNCARGTNGAYYTNGAYAAYAGYGARGCNGTNCARMGNGAYTTYGTNAARYTN TCNCARTCNYTNCARATHCARYTNGARAARATHMGNCARGCNGARACNGARATHMGNTGG CARCAYGARGAYGAYGTNGARGAYTGYAAYAAYTGYAARCARCCNTTYACNGTNACNMGN MGNAARCAYCAYTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CARCARCARCAYTCNCCNAAYAGYYTNGCNGCNATHGGNCCNMGNAGY GTNYTNGGNGCNCCNGGNATHCCNGGNGCNGGNCCNATGAAYAGYATHCARAARCARGCN GGNTTYAAYGGNGGNCCNATGGCNAGYTTYGCNACNAAYTAYGGNTTY------ACNMGN TCNATHGAYTCNCAYCCNACNATHGAYYTNTCNGAYTTYCCNTCNYTNAGYAGYMGNTCN TCNAAYACNCCNAAYCCNATGCCNACNGCNMGNAAYTAYGTNGGNATGGTNAGYAARCCN GTNCARGARAGYCARCCNGARTTYAAYATHACNCARGARGARTTYCCNGCNYTNCCNGGN TCNCAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GGNGGNCCNATGMGN---------GAYGAYTCNCCNCCNMGNAARATGYTNTCN TCNMGNTTYGAYTCNGCNGAYMGNCCNMGNGCNCCNATGGAYMGNMGNGAR---AGYMGN TAYGAYGAYAGYTTYGAYMGNGGNCCNCCNCCN---MGNTCNMGNGAYYTNTAYGGNACN CCNCCNMGNGARMGN------------------------------ATGGCNGCNACNMGN GAYMGNGAYTAYGGNGTN---MGNGGNGCNGAYTAYYTNAAYTCNMGNGCNGARTAY--- TCNTCNMGNAGYTAYTCNCCNACNMGNGAYACNGCNTAY---GCNTCN------------ TAYMGNAGYTAYTCNCCNMGNGAYCAYYTNTCNTCNMGNGAYTAYCCNCCNCCNMGN--- AGYAGYGAYTAYGGNGGNTCNMGN---GGNACNGAY------YTNTCNAGYYTNMGN--- GAYTAYGGNAGYTCNACNMGNGAYTAYACNGGN---------MGNMGNGAYGAYTAYCCN ACNTCN---------MGNGAYTAYAGY------------------------TCNGCNMGN GAYTAYCCNTCNTCNMGNGAYTAYCCNTCNTCNMGNGGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MGNYTNGCN MGNAARCARGGNGARGGNGGNGGNGGNTAYYTNYTNCAYTAYTCNATHTAYGTNGGNGTN CCNCARACNAAYMGNYTNGGNGTNGAYTAYAARACNGTNMGNGTNGGNTGYGTNCCNACN GCNTTYGGNACNATGAAYGTNGGNYTNGCNCAYMGNACNCARATGYTNATHTCNCCNCAR ACNGGNYTNTCNTCNGGNGARATGTTYGARGTNAARGARGAYCAYGAYAGYYTNACNMGN CCN---------------CCNTTYCCNACNGARCCNCARCCNTGY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARYTNCARYTNYTNTGGCARYTN MGNCCNTCNAAYCARYTNYTNGGNAGYGTNMGNYTNTAYTTYCARCCNGARTAYACNCCN GAYGGNMGNCAYGARCARACNGGNGARGAYGARGTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CCNGCNGAYTTYTCNCCNTTYATGYTNCARMGNAAYAGYCAYGAYATHCCNAAYATHGAY TGYMGNACNCAYGGNGGNATGCCNAARACNCCNCCNACNMGNCARAARCCNTCNATHGGN CAYGCNGTNAGYGGNCCNCCNGTNAGYGTNTCNGGNGARGGNMGNCARCCNGTNAARGTN ATGAAYYTNCCNCCNGGNTCNTCNTCNGGNGGNCAYGTNATHCARGGNCCNCARCCNTCN GCNATGMGNTAYATHMGNATGAAYTTYGGNGAYACNGGNGGNGTNTGYACN--------- ---------------------------------------------GTNGCNNNNGGNGGN AARGAYTGYGARGGNGAYAARGTNGARAARAARGAYTGYTCNGGNCCNCCNTGYCCNGCN YTNGTNAARAAYATGCAYYTN------TGYCCNAARGARAAYTTYACNTGYGCNAGYCAR AAYATGTGYGTNGGNATGGCNCARMGNTGYGAYGGNACNGTNGAYTGYCAYGAYGCNAGY GAYGARTAYGARTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------GARGTNYTNAARCARATHACNGARYTNTGY GGNGCNAARMGNYTNGGNCAYTTYGGNMGNAGYCARTTYTAYATHGCNYTNMGNYTNGTN GCNATHGCNCARACNGGNYTNCCNGTNACNGTNGARTCNYTNAAYTCNGGNMGNGAYATH CAYYTNCCNMGNTTYGARCARGCNATHTCNGTNGGNAARAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GAYGAYGGNAARGGNGTNATHGARAARGAY GARATGGGNAAYGCNATHTTYAARGTNMGNTTYGAYATGAARGAYTAYMGNCCNGARGAR ATHAAYGTNAARATGGAYAAYGAYAARATHATGGTNTCNGGNAARCAYGARGARAARAAR GGNGGNTCNTCNGTNTCNMGNGARTAYAAYMGNGARGTNCAYATHCCNMGNGAYGTNGAY CCNYTNACNYTNCARTGYACNYTNAGYCCNGAYGGNGTNYTNTCNGTNCAYGCNCCNYTN CCNAARTCNTCNCARACNCARGTNGGNGTNCARAAYAAYMGNATHTCNACNCCNACNGCN CCNACNTAYAARMGNGCNGARTCNGCNCCNGCNCAYCCNGAYCAYGTNGTNCCNATHTAY MGNCCNTCNCAYAGYYTNAGYGCNATHGAYGCNGTNATGCARAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNMGNCARAAYTCNGCNCARCARCAYGARGGNGAYGGNGAYTGYGAYTCNACNCCN ACNACNCCNTCNGAYAAYACNCCNAGYGCNAGYAGYACNTGGAAYAAYTGGCCNAAYCCN CCNGGNYTNGCNMGNGCNGAYCCNGCNMGNCCNCAYACNATHAGYTCNGCNTAYGARAAR GGNNNNNNNNNNNNNGCNYTNAARCCNGAYYTNTTYGARCCNCCNTCNGARGAYGTNGAR YTNMGNAAYAARCAYGGNMGNTCNTCNAGYACNTCNTCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TGGAARAARCARCCNGCNCCNGGNGAYCARGTNCAYCARAGYYTNMGN TGGGCNGTNMGNGCNAARATGYTNCARAARGAYGARGTNAARYTNCARCCNMGNATGTAY GTNCCNAAYAGYTAYGTNGTNCCNACNATGAARAAYMGNAAYAGYYTNMGNTTYCARGTN MGNAARGAYYTNGCNGARGGNMGNATGCCNAARTCNGGNTTYTAYCAYGAR---CCNACN ------TTYGARAARGTNCARAARGTNAAYMGNCARYTNCAYCARGCNAAYGCNGARTGG CARAGYMGNTGGGARTCNYTNAARCARCARATGGAYMGNMGNGTNGAYGARYTNGARAAR AARAAYGCNGARYTNGARMGNGARATGGAYGARTAYGAYMGNAAR------------ATH GCNGAYTTYGARACNGCNATHATGGARGCNAARTCNGCNAARGAYGCNGCNCARYTNCAR ATGATGGARTCNGARMGNGARTGYAARAARCAYAARGAYCAYGCNGCNGCNYTNATGCAR GAYYTNGAYAAYGTNMGNMGNGARAARCARGARATGGARGCNGARYTNTCNMGNYTNAAR AGYTCNACNAGYAGYGCNCCNGCNACNGGNACNYTNTCNMGNTCNGARATGGARACNGAR ATHGCNATHYTNMGNCARCARYTNACNGTNTTYGARGARGAYTTYACNMGNGARMGNCAR GAYMGNGCNAARAAYCARGCNGCNYTNGAYCARYTNAGYMGNGARAAYAARAARCARMGN ATGGCNGCNGAYAAYAAYGTNMGNGCNGCNCARGTNCARYTNMGNAARAARGARGARGAR YTNAGYGTNAARAGYAAYACNGTNGCNCAYYTNCARMGNCARATHGTNGARYTNMGNGGN AARYTNCARACNGARCARGARGTNAAYAAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CCN MGNGGNYTNAGYAARGARGARGTNGARGCNATHGTNMGNGGNATHYTNGTNTCNGARACN GARGCNATHMGNYTNGGNTTYTCNGCNCARYTNAARACNTCNCARACNCARYTNCARACN GAYYTNGTNGGNYTNYTNCARMGNYTNGCNGAYYTNGARAARGARYTNTCNGAYGCNMGN YTNYTNGCNCARGCNACNGARCARYTNGCNGAYGCNMGNYTNGCNYTNGARAARGGNAGY YTNGARCARTCNGARTCNACNTCNGCNTAYATHGCNGGNYTNGARACNCARYTNAARGAY YTNGAYGTNMGNATHGCNGARYTNCARMGNTCNCARGCNGARYTNAGYGCNTCNATGAAR TCNTGYTGYCARAAYAAYACNGCNATHATGGCNGCNATHGCNTCNCARGTNCARGARGCN GTNAGYCARATGAGYACNGAYCARGAYGGNMGNGAYYTNGTNGCNYTNGCNGCNMGNYTN GGNAAYCARTAYGTNGARMGNTCNGARYTNGAYAGYMGNYTNGARGCNATGAGYAARGAR ATHGCNGAYMGNYTNAAYATGYTNATHGTNGARMGN------TCNGARGARGCNGCNGAY ---------------------GARYTNACNGTNMGNTCNATHGTNGAYGARGCNYTNYTN MGNTAYAGYGCNGAYAARACNGGNYTNCCNGAYTAYGCNYTNGARTCNGCNGGNGGNAGY GTNGTNAGYGTNMGNTGYTCNGARACNTAYTAYAARAARACNGCNYTNGTNAGYYTNTTY AGYATHCCNYTNTGGTAYACNTCNAAYTCNCCNMGNACNGTNATHCARCCNGAYGTNTAY CCNGGNCARTGYTGGGCNTTYAARGGNCARTCNGGNTAYATHGTNYTNCARYTNAGYGAR CCNATHAARGTNACNGGNTTYACNYTNGARCAYATHCCNAARTCNGTNGCNCCNAAYGGN AARATHGAYAGYGCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNTTYMGNTCNTCNACNYTNAAR GTNTTYAARAARCARGGNGARTCNTCNGCNCARGGNTCNATHTTYATGAARGAYGTNTGY AARTGGTTYGCNTAYGGNGARTAYACNAAYGGNATGTCNGARMGNCCNGAYYTNCCNACN GGNGCNTCNGTNAGYTGYGTNATGGCNATHCCNCARAARCCNAGYAGYAARGCNAARATH CAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNATHGGNTGYTAYATGATHYTNAAYYTNGTNGGN MGNYTNGCNGCNGGNMGNGTNYTNMGNATGTTYATGYTNTTYCCNACNATHGARMGNATG GCNGCNTCNCCNAAYGGNMGNACNYTNACNCCNGTNTTYAAYTAYYTNMGNTGGYTNGTN GTNYTNGCNGCNGCNYTNATHGCNYTNGTNCCNGGNGCNGTNAARGCNMGNYTNGTNGGN TGGCAYYTNGGNGCNTTYCARTAYCCNGARTGYGTNMGNYTNGCNGCNYTNGGNACNYTN AAYCCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TGYMGNTGGAARGARCARACN GARGCNGAYCAYGARTCNCAYATGMGNCAYGTNTGYTAYMGNGGNYTNYTNGARYTNAGY GAYACNGARGCNTCNCARGTNCCNCARTGGGTNMGNAARTGYGAYTTYTCNTCNTTYGAY GCNTTYYTNGCNTCNTGYTTYCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CARCAYGCNMGNAGY MGNYTNMGNACNATHATGGCNACNYTNAGYGARAARATGGTNGTNATGAGYGARYTNYTN ACNATHCARTGYAAYGCNATHGCNGCNCARMGNYTNMGNMGNGCNTCNCARATHGTNATG YTNTAYMGNMGNATHTAYGGNGARMGNYTNATHCARCARMGNYTNGGNGGN---ATHGGN CARTGYAARGGNMGNCCNATHTTYGCNYTNYTNTCNGCNTGYATHTTYCARTGGTCNAAY GARMGNGTNGAYGAYGAYGARYTNAAYMGNTGYATHTGYGARATGGAYGARGTNTGYACN GCNATHGCNAARTCNAARAARTCNCAYGARCCNYTNGCNGAR------------------ ------------------------------YTNATGGAYGGNTGGGARAARYTNATHGAY MGNGAYCAYTTYAARGTNTGGMGNAARGCNGTNCCNGAYAGYTAYYTNTAYAARTAYAAR GTNTAYGGNACNTTYTCNGAYATHCCNGCNMGNGCNTTYTAYAAYACNCARATHGAYYTN GARTAYTGGAARGTNTGGGAYTGYCAYACNATHGAYGCNTGYATHYTNGAYAARGAYCAR GTNACNGGNTCNGARGTNGTNCAYTGGACNTAYAARTTYCCNTAYCCNATGTAYCCNMGN GAYTAYYTNTTYGTNMGNMGNTAYAARACNGAYGTNGARAARAAYACNATGGTNATHACN GCNMGNGCNACNTCNCAYCCNMGNTGYGARGTNTCNACNAARTAYGTNMGNGTNCAYACN TAYMGNTCNCARATGGTNATHAARCCNCAYACNACNTTYGAYGARAAYGGNYTNGARTAY GTNATGACNTAYTTYGAYGAYCCNCARACNAAYTTYCCNACNTTYGCNTAYAAYTGGATG GCNTCNTCNGGNTGYCAYGARTTYYTNGARMGNGTNCAYMGNGCNGCNMGNCARAARCAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AAYGAYAARGAYGARGAYGAYYTNTTYGGNGGN GARGGNTCNGARATHAARYTNGAYTCNGAYGARGARGARGARCCNGCNGAYGAYGAYGAY GARAAYGAYGARGARCARGGNGCNGGNGCNGTNAARTCNGARCCNTCNGARCCN------ ------------------------------TCNCCNCARATHTCNGTNTCNGARGTNYTN ACNGCNAARACNAARATHACN---CCNGCNYTNCCNAARGAYGARYTNACN---GARAGY GARGARAARGARGCNGCNTAYGARATHGARATHYTNATHACNGAYACNCARAARATGGGN GAYGGNATGTCNGCNTAYATHGTNTAYAARATHGTNTGYAARACNACNAAYCCNGCNTAY MGNAAYCCNGARAGYACNGTNYTNMGNMGNTTYAGYGAYTTYYTNGGNYTNCAYGCNAAR YTNGCNGARAARCAYGTNCCNGARGGNATHATHGTNCCNCCNGCNCCNGARAARAGYGTN ATHGGNATGACNAARGTNAARATGTCNAARGARGARTCNGGNTCNTCNGAYTTYATHGAR MGNMGNMGNGCNGCNYTNGARMGNTAYYTNATHMGNACNGCNAGYCAYCCNAARYTNGTN AGYGAYTCNGAYTTYGTNGARTTYATGGARAARGAYGGNGAYYTNCCNAARGCNACNAGY ACNTCNGCNYTNAGYGGNGCNGGNGTNATGMGNYTNTTYCAYAARGTNGGNGARTCNYTN GARAARATHACNYTNAARGTNGAYGARAGYGAYGARTGGTTYGARGARAARCARCARCAR ATHGARGCNYTNGAYYTNCARYTNAARAARYTNCAYACNAGYYTNGARGCNYTNTCNGCN CAYMGNAARGARYTNAGYTCNGCNACNGCNGTNTTYGCNAARAGYGCNGCNATGYTNGGN AAYGTNGARGARCAYACNGCNYTNTCNMGNGCNYTNTCNCARYTNGCNGARGCNGARGAR AARATHGARTGYATHCAYMGNCARACNGCNGARCARGAYTTYTTYACNATGGCNGARYTN GTNAARGAYTAYGTNGCNYTNATGGGNGCNGTNAARGAYGCNTTYCAYGARMGNGTNAAR ACNTAYAARCARTGGAARGAYGCNGARAGYACNYTNGGNAARAARMGNGARGCNAARGCN AARTTYGARYTNCARGGNAARTCNGAYAARATHGCNCARACNCARGCNGARATHACNGAR TGGGARCARAARGTNGARAARGGNCARGARGAYTTYGARAARATHTCNAARACNATHMGN AARGARGTNGTNMGNTTYGARAARTAYMGNGTNGARGAYTTYAARAAYAAYGTNYTNAAR TAYYTNGARACNYTNATGGARAAYCARGARAARYTNATHAARTAYTGGGARATGTTYYTN CCNGARGCNAARGCNATHGCNTCNCAYGAYGARACNGCNAARGGNCCNMGNCARMGNGCN YTNGARMGNYTNMGNCARMGNCAYTTYGAYGAYTCN------------AGYAGYGAYGAY GTNYTNGAYACNTAYMGNTCNGTNCARACNGAYCCNTCNCCNMGNACNGAYMGNACNGCN MGNYTNAARGCNGCNAAYGCNMGNATGAARMGNAARAARMGNGGNGCNGCNMGNMGNMGN TAYACNYTNCCNCCNCCNCARYTNAGYGAYGAYGARGGNCCNGARTCNTCNGAYGAYMGN TAYGARGARTCNAARGTNAARGARGARATGACNACNCARGAYATHGGNCARTTYGAYGAR AARAARGGNAARMGNGTNTGGTTYTTYMGNAAYGGNGAYACNAAYTTYAARCCNAARMGN YTNYTNGTNAGYAAYAARACNCAYMGNAAYTTYGARGTNYTNYTNGTNGAYYTNAGYGCN CARATHCARACNACNACNAGYGTNAARCAYGTNTTYTCNTGGCCNGAYGGNMGNGARATH AARAGYYTNACNGARYTNGARGAYGGNMGNTAYTAYGTNGCNTCNTCNACNAARATHYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GTNCCNCCNCCNTCNCCNTGGGCNAARGCN MGNGAYYTNACNGTNACNACNYTNATHGTNGGNGGNGTNTGYTAYGGNATHTAYCAYTTY TTYCARATGTAYATHMGNCCNMGNYTNYTNGGNMGNTCNGCNGAYGARAARMGNYTNGAY CAYYTNCARGCNGARGTNATGGARYTNCAYAARAARGTNGCNGARTCNAAYGARMGNATH GCNAGYACNYTNAARGAYATHCARTGYGCNATHAAYGARCARAAYAAYMGNYTNCCNGTN ATGGAYGAR---AAYMGNGGNATHGCNGAYYTNAARGCNGAYATHGCNTCNYTNAARGGN YTNYTNYTNACNMGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GAYTCNGGNCCN ACNCCNACNCCNMGNAARCARGAYATHCARCARGARAAYGARGARGARGARGARGARGGN ATHTAYGARAAYCARCCNATHATGMGNCARGAYGTNGCNMGNGARTCNGAYAARGAYATH GGNGTNGARYTNCCNGCNGTNGGNACNGCNTCNAGYYTNMGNACNAARTTYATGACNGGN CARGCNGARGGNGCNAGYCCNMGNGGNAARMGNGGNATGACNCCNCCNGAYAGYTCN--- GGNCCNTCNGARTTYGTNTCNGARCCNMGNAGYTTYGTNGARAARTAYGARGGNCAYGCN GARTCNGGNGTNTTYGARAGYGARCCNGTNMGNGCNGGNGAYATGGTNACNTCNGARACN GTNYTNGARGARAGYYTNCCNCARCARGGNACNGCNMGNAAYYTNGCNGCNMGNTTYAAR GARATGGARACNAARGGNTCNGTNCCNCCNTCNGCNGGNAARMGNGARATHACNCCNGAY MGN---TCNACNMGNGTNGARTAYGTNTCNGARCCNMGNGCNCARGTNGARCAYTAYGAR GGNMGNGCNGARGCNGGNGTNTTYGARAGYGARCCNYTNCARAAYCCNGARGTNATHMGN GCNGCNGAYCARATG---CARGARGARYTNCCNGARCARGGNATGGCNMGNAAYATHGCN GCNMGNTTYAARCARATGGGNTCNTCNGARAGYGCN---GGNACNCCNMGNGGNAARMGN GARATHACNCCNGAYACNACNGGNMGNGTNGARTAYGTNAGYGARCCNMGNGGNMGNGTN GARCARTAYGARGCNCARGTNGARGCNGGNGTNTTYGARAAYGARCCNCARCAYCARCCN GAYGTNATHMGNTCNGAYGARATGYTNGARGARGCNATGCCNGARMGNGGNTTYACNMGN AAYGTNGCNGCNAARTTYMGNGARYTNGARACNACNGCNAARTCNCCNCCNYTNTCNCCN GGNCARMGNAARGARTTYACNCCNCCNMGNGARGARGTNGGNCARMGNCARGCNGGNGTN TAYGARAGYACNCCNCARGTNAARGCNGAYGTNGTNCAYGCNACNGAYGCNCARGARGAR GTNYTNCCNGARMGNGGNTCNGCNAARAAYATHGCNCARMGNTTYMGNCARTTYGARGCN GCNAGYAARTCNCCNACNAGYCCNAARCCNAARAARGARTTYACNCCNCCNCCNGCNGAY TCNGGNGTNTTYGARAAYCARCCNAARGCNTTYGTNTCNGARTAYAAYCCNCCNCCNGAR AGYGGNATHGTNGARAAYCARCCN---GTNATGMGNGARGAYGTNGTNMGNGARGCNGAR CCNCCNCARTAYGARAARGARYTNCCNGARMGNGGNATGGCNMGNAGYYTNGTNAGYMGN TGGMGNCARATGGARTCNGARTCNGCNAARGTNACNTCNCCNGGNTCNTCNGGNMGNGTN AARGARTTY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CAYGCNYTNTCNAARTCNAARYTNGAYAAYGTNCCNCCNCCN CARGGN---------AARGCNATGAARATGAARGCNGTNMGNGARGARTCNYTNGAYTTY ATGMGNGGNGTNATGGAYGARTGYACNCAYYTNGGNAAYTTYACNGTNCCNGTNGAYCCN AGYYTNATHATHATHATHYTNGCNAARCARGAYGCNTAYATHCCNTGGAAYGGNGTNATG MGNYTNGAYGARATGTGGCCNGGNGCNGARGTNMGNTAYGTNGAYAARGGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GCNCCNTTYAARAARTGY AGYTCNGCNTCNAARGCNGGNCARMGNTGYCCNAAYGCNGCNCCNMGNAGYGAYMGNAAR GAYGGNYTNTGYGCNGAYCAYTCNMGNMGNAAYATGYTNATGMGNCARMGNTCNTCNMGN AARMGNMGNCCNMGNGARACNTCNGARAGYYTNYTNGARGARYTNGCN---GCNTAYAGY TCNATGTCNAGYTCNAAYCARATGGAYGCNAARMGNGCNAARYTNGCNGGNGAYACNYTN GCNAGYMGNGCNYTNGARTAYGCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARAAR GARGCNATHGCNACNACNATHAARACNYTNAARGCNGAYAARCARMGNYTNGTNGTNAAY TTYGARAGYAARGCNTCNGARGTNAAYGGNYTNATGAARGARATHGARAARYTNAARGAR GCNAAYAAYTCNGCNGAYTAYMGNATHAARTGGTTYCARAAYAARYTNAARGCNGARYTN GAYGTNCAYAARGARACNAARGGNACNYTNGARAARACNAAYGCNAARYTNAARGARGCN AARGARGARACNGARATGATHMGNMGNGARTGYCARGCNATHATHAARCARTAYCARGAR TCNGARGARATHAARTCNAAYAGYYTNGAYAARGARYTNAARATGAARGARACNGARYTN CARATGCARYTNCARGARAARAGYGAYTCNGARGARYTNTAYYTNMGNYTNMGNCARGAR YTNGARTCNYTNAARTCNCARCAYAARGAYATHYTNGARGARTCNMGNGTNYTNMGNGAY AARGTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYAARMGNMGNYTNAAY AARYTNGCNAARYTNGAYCCNAAYGGNAARATGTAYAARGTNTGYAARYTNTGYTTYGAR GARGGNGTNACNACNGARTCNGTNTCNMGNAGYGTNACNGCNGCNTTYATGCAYATGMGN GCNMGNTGYAARMGNYTNATHCARGGNTTYGARAGYAGYATHGGNAGYTCNGARATHAAR MGNACNYTNCAYGARYTNMGNAGYGTNGTNTCNACNCCNGAYTGGATGAARTCNAGYGTN TGGATHCARGARAAYATGGCNAGYCARTGYCARYTNTGYCARGARGCNTTYGCNYTNATG MGNAARAARTGYTTYTGYMGNGTNTGYGGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATHACNGGNTTYMGNGARGTNGGNGARCARYTNYTNTCNAARTTYAARTGGGGNMGN GTNTTYTTYGAYYTNAAYAARCARYTNYTNGAYACNTAYGTNGCNTGYGCNGAYAGYGCN GCNGTNGTNGCNGCNCARGAYMGNYTNYTNCARGARATGAARGCNGARGAYGARMGNGAY AARGGNMGNGAYTGGACNGAYATHGAYCCNGAYATGGARACNCAYAAYCCNAAYMGNCCN ------YTNYTNGAYGAYATGAGYTCNGAYGAYGAYAGYGAYGAYGAYTGYAAYGAYGAY AAYGAYAGYCAR---------GAYAGYGAYGAR---------GARGAR------------ ------------------TGYATGGCN------GGNGAYTTYGARYTNGCNGGNGCNTTY TTYATHGCNGARAARAAYCCNAAYGARAARGCNAARGTNGAYTTYATHTGYAAYCAYGTN AGYGGNATGGTNGAYATHATHCAYTGYATGGCNGAYMGNYTNATHCCNTGYGTNCCNGAY CARYTNCARAGYATHGTNMGNAAYGTNYTNCCNGCNAARGAYAGYYTNACNMGNTTYTTY ACNACNGTNTGYAAYAAYMGNGARGCNYTNAAYGAYGARTGYATHGAR---GARCAYTCN ACNTCNGTNATGCARTGYTCNAAY---------GGNYTNYTNTCNCAYYTNGTNCARGGN ---GGNMGNGAYGARATHYTNAAYGGNTAYATGTGYCAYGTNGTNAAYATHTAYACNGGN TGYGTNGAYAARTAYGAYGCNGAYTGYTCNTCNGAYCAYGTNAAYGTNATHACNAARGCN ATGAAYGAYYTNTTYTCN---------TGYGGNGCNGTNAARCCNYTNCCNCCNAARTCN GCNCCNGGNYTNAARGAYATHYTNGTNMGNGGNCARCCN---YTN--------------- ---------------TGGYTNMGNCCNACNACNYTNGAYGARYTNYTNGCNATHAARAGY GARTAYCCNCAYTGYAARYTNGTNAAYGGNAAYACNGARATHGGNATHGARACNAARYTN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNGARTCNCCNGCNACNGTNTCNCARAARYTNCAYTCNYTNYTNCAR TCNYTNCCNACNATHGCNGGNGARGGNAARMGNTAYAAYAGYYTNGTNMGNACNGGNTCN YTNMGNYTNTAYMGNAGYTCNTCNATGGAYYTNAAYCCNACNCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARGAYATGYTNGAYAARTCNAARGARYTNACNTGYMGNACNGAYGAR YTNAARTGYGTNAARGAYGARYTNAGYMGNTAYAGYACNGGNAARYTNGARACNCARGAY GTNTCNGCNCARACNGTNGCNGGNGARGTNTCNACNGTNGARAAYYTNAARCCNTCNGTN ATGTCNGARAARGAYMGNGTNATHGCNAGYYTNCARGARGARGTNGGNGTNYTNAARATG GARYTNGARAGYYTNMGNCARCAYCARGARTCNGAYAARCARCARTGGYTNGAYGARAAR AAYAARGTNGTNMGNTAYCARAARCARYTNCARYTNAAYTAYGTNCARATGCARMGNAAR AAYGCNACNYTNGARTCNGARGTNCARCARYTNACNYTNGARYTNGARAAYMGNGAYATG AARYTNATHGCNYTNAAYGGNGARGARAGYGTNTGY------TTYYTNGAYTCNTTYTCN ACNGCNGCNATHYTNAAYYTNGGNGTNYTNGCNTAYATGACNCARTGGAARCCNACNCCN GAYTCNYTNYTNCCNTAYTTYATHACNATGGGNYTNTGGGGNGTNAGYGAYGGNATHTAY ATHTCNCARACNAAYAGYYTNATGGGNGTNGTNTTYGCNGAYMGNTCNGARGARGCNTAY ACNGGNYTNMGNGTNTGYCARGGNYTNGGNATGGCNATHGCNTTYGGNTAYTCNACNATG TTYTGYATGCARACNAARATHATHATHGTNGCNGTNYTNTGYGTNGTNGGNYTNGCNGGN TAYYTNYTNATGGARYTNYTNCARCARMGNCARACNCARCCNMGNAARACNTTYYTN--- CARACNTCNGTNYTNGAYTCNACNMGNYTN---TAYTGGTCNATHGGNTTYMGNCARTTY CCNGARGAYACNATHGTNACNACNAAYGGNGGNMGNTAYGAYGTNAAYATHGGNCARMGN YTNMGNMGNGCNGTNTTYTGGAAYGAYAARCCNGGNATGGTNMGNMGNTGYTCNTGGTTY TAYAARMGNGARGGNGAYAAYMGNTAYGTNCCNTAYGAYGARGAYACNGCNYTNMGNYTN GARAAYGARTAYAARAARGCNYTNGARACNAAYATGTGGCAYAARMGNATHGARYTNCCN GGNAAYGARACNATHGTNATGCAYAGYGCNCARGTNATHGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNTCNTAYAARCCNGGNTAYGCNMGNATHAARGARGAR TTYYTNATHCAYAAYCAYAARCCNMGNYTNGCNTCNGARTAYYTNAGYGCNGARACNAAR GARAARYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ACNAGYGCNGAYCAY ACNAAYTGGATHYTNGAYACNATHGAYCAYYTNMGNMGNMGNAARGCNMGNCCNGAYYTN GARMGNATHTGYCAYGTNGTNAARMGNMGNTTYGGNYTNAGYCAYAGYGAYACNGARGCN AARYTNGAYAARYTNGTNGAYGCNGARATHGTNGTNAARGTNGAYTAYAARGGNAAYACN AGYTAYMGNAAYGCNGCNAARTGGMGNAARAGYYTNYTNGGNGGNGCNGTNYTNAAYTCN AARACNGCNAGYGCNAAYATHMGNACNGCNGTNMGNGARATHAGYMGNCARMGNMGNGCN GGNGARAAYAAYAAYAAR---------------------------------------ACN GAYAGYGARMGNAAYGGNGCNGCNGAYAARATHGGNGTNAARGCNGARGARATHGARGAR TGGYTNMGNAARAAYAAYAGYGCNTTYGAYGARYTNAARAGYCCNTTYAAYGTNATHYTN AARMGNGARATHGAYGCNGGNTTYYTNGARMGNYTNCCNAAYGGNAAYYTNGCNGTN--- ---------------------------------------------GCNGARAARAARGTN CCNATGGAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNGTNTCNGARYTNCARAARAGYAAYGCNGCNYTNYTNGGNYTNGTNGAR--- ---------TCN---------MGNAGYGGNCCNYTNACNGTNCAYAARYTNGARGCNGAR YTNMGNGAYYTNMGNGCNGARAARGARCARATGATGGCNGTNGTNAAYGARAARACNMGN GARAGYTCNTCNYTNAARACNGARYTNCAYMGNYTNATGGGNGTNGTNGCNGCNGGNCAR GCNGCNYTNGAYAARYTNCARCARGAYAAYMGNGAYYTNAAYCARMGNCARCARACNCCN CCNMGNGAYAAY------GARGAYGARCARATGCARMGNGARGCNYTNGCNAAYATGGCN MGNYTNGTNMGNGAYMGNGARACNGARATHGARGCNYTNMGNCARAARAAYGARACNYTN YTNGCNGTNYTNCARGARTCNGGNGAYTCNTCN------GGNAGYCARYTNGARCCNYTN YTNCAYGARAARGARGCNYTNTCNAARCARYTNTCNGCNATGGCNAGYGARMGNGARCAR YTNATHGCNYTNGTNACNCARAARCAYTCNGARTGYYTNGCNTAYCAYGCNGARGCNCAR AARTTYTCNACNGCNYTNTCNGARTGYCARACNMGNGARGARACNYTNAARAARGAYTAY AGYTCNYTNATGACNCARTTYGARGAYAARTCNCARGCNGTNGTNGCNGCNCARACNGAR YTNYTNTCNTGYAARCARMGNYTNGGNGAYYTNGARAARMGNAAYGGNGARYTNYTNCAR MGNGCNAAYAGYGARAGYTCNATHGAYTCNTCNGARTAYTCNAGYYTNGARGCN------ ------------------GAYYTNGAYMGNGTNAARGARYTNGAYYTNYTNACNGTNGTN GGNGARMGNGAYGARACNATHCARTCNYTNAGYCARMGNGTNAGYGARYTNGAYCARGCN GTNGCNGARMGNGAYTCNGAYMGNAGYCAYYTNMGNAARCARGCNGAYAGYYTNAAYTTY CARGTNTCNGARYTNCARGCNCARYTNGCNGAYYTNMGNACNGARCAYGCNAGYAGYGAR GARMGNACNYTNCARCARAGYACNGARAGYCAYGAYYTNMGNGARACNATHAAYAARYTN AAYYTNGARACNYTNCARAARGARCAYGARGTNGCNTCNYTNMGNGARCARGTNGCNACN YTNACNTCNYTNYTNCARGARCARCARGGNGARCARGGNCARGTNGCNAARYTNATGTCN CARCAYGARACNGCNACNGCNACNATHCARCARYTNCARCARCARMGNGAYCARATGAAY ATGATGGCNGARCARMGNYTNCARGARATGGARACNYTNMGNGCNGARATHTTYMGNATG AARGARAARGARGCNAARCARGCNAARGARYTNGARMGNYTNMGNGGNCAYYTNATHCAR ATGGARGARGGNTAYACNAARGARGCNYTNGARGCNGARGARMGNGARAARGARYTNMGN ACNMGNYTNGCNYTNGCNGARGAYCARGTNYTNACNTCNAGYACNAARGTNCARATGGCN AGYCARGARATGATGCARGARGTNGARAGYYTNCARCARCARYTNCAYAAYGTNAGYAAY CARMGNGAYGCNGCNTAYACNCARYTNTCNGGNGCNCARACNCARTGYCARCARTAYGCN AGYTCNYTNGCNAAYYTNCARYTNGTNYTNGARCARTTYCARAARGAYAARGARACNYTN GTNGCNCARGARACNGARMGNTAYCARGCNGARTCNAGYMGNYTNACNGARGTNGTNMGN GARYTNMGNGARGARYTNGARGCNACNMGNGCNGAYYTNAGYGARGCNYTNGAYGGNYTN GARGCNGCNTCNMGNYTNAGYGARCARYTNGAYMGNAARGARGARGCNYTNGCNGCNYTN MGNGARGARGTNCARYTNMGNGARAAYGCNYTNAGYGCNGCNGARGARGARATHMGNAAR YTNACNAGYAGYACNGARGCNAARGTNGAYMGNCARYTNATGCAYAAYATGGTNATGGCN TGGYTNACNTCNCCNGAYAGYAARAARAAYGARATHGTNCAYYTNATHGGNAAYGTNYTN AAYTTYAGYCARGAYGAYTTYAAYAARATHAGYAGYAGYCARAGYCCNGGNGGNTGGGTN ACNTCNYTNTTYACNAARGCNTCNCCNTCNACNCCNGARMGNAARMGNGCN------GAY CARTCNTTYTCNCARYTNTTYGTNAARTTYYTNGARMGNGARTCNTCNCCNCCNCCNACN CCNGTNMGNYTNCCNGCNGAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATHGGNAARGGNMGNTAYGGNCARGTNTGGMGNGGNMGNTAYMGNGGNGARGAYGTN GCNGTNAARATHTTYTCNTCNMGNGAYGARGCNAGYTGGCARMGNGARACNGARATHTAY AAYACNTGYYTNYTNMGNCAYGARAAYATHYTNGGNTAYTAYGGNTCNGAYATGACNTCN MGNAAYTCNTGYACNCARYTNTGGYTNATHATGCAYTTYCAYAAYAAYGGNTCNYTNCAY GAYTAYYTNCARMGNTCNGAYATHGAYMGNGARGARATGYTNATHYTNTGYCAYTCNGCN TCNGCNGGNYTNTCNCAYYTNCAYGAYGARATH---------AAYGGNAARCAYGGNAAR CCNGCNATHGCNCAYMGNGAYYTNAARACNAARAAYATHYTNGTNAARGCNAAYGGNCAR TGYTGYATHGGNGAYYTNGGNYTNGCNGTNATHCAYMGNCARAARGAYGGNGTNGTNGGN MGNAAYACNAARGTNGGNACNAARMGNTAYATGGCNCCNGARYTNYTNGCNGARACNATG AAYYTNCARTTYTTYGAYTCNTTYAARTGYGTNGAYATHTAYGCNYTNGGNYTNGTNYTN TGGGARATHGCNMGNMGNGCNMGNCCNTAYTCNGARGARTAYMGNGTNCCNTTYTGGGAY GTNGTNCCNGCNGAYCCNTCNTTYGARGAYATGAARAARATHGTNATGGTNGARCARCAR MGNCCNCCNATHCCNAAYCARTGGTCNTCNGAYCCNYTNATGMGNCCNATGACNCARATH ATHMGNGARTGYTGGGCNCARAAYCCNAARGCNMGNYTNTCNAGYYTNMGNGTNAARAAR ------------------------------------------------------------ ------------------------------------------------------------ ATGYTNTTYAGYGTNGAYGAYTGGAARCARGGNCARMGNYTNYTNTGYGARGAYCARAAY ---------YTNTTYCAYGCNCAYTTYGCNTGYYTNTCNMGNTTYGGNCCNMGNATHGCN TCNTGYATHYTNATHMGNTCNCARATGTTYMGNAARGCNGTNACNGAYGCNGGNYTNTTY GCNCAYMGNAARYTNCAYGAYATHACNTGYAAYTTYGCNGARAAYATHGTNAAYTGYYTN GARMGNCCNYTNTCNMGNTCNTGYTCNCCNGAYGTNGTNGAYATHATGGTNGGNGCNYTN CAYMGNTTYYTNCCNCCNGCNTGYGCNCCNATHCCNGCNGGNGGNTCNYTNAGYGCNGAY AAYGTNGARAGYCAYGGNGARMGNGARCCNAARATGGTNGARGCNATHATHYTNGARGGN GGNGARGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYAGYGAYYTNAAYYTNATHGARCCNACNTTY ACNTCNCAR------ACNCARACNTCNATGATGCAYACNTAYGARACNATGGARACNATG AAYGTNAARACNTCNCCNGCN---------TCNTGYCCNGCNACNTTYAARMGNCAYYTN GAYAGYACNTCNGGNTAYYTNACNGARAARGAYTCNAARGCNTGGCARAARGARMGNATH AARAARGAYAAYCAYAAYGCNATHGARMGNMGNMGNMGNTAYAAYATHAAYGAYMGNATH AARGAYYTNGGNAAYYTNYTNTCNGAYGARTAYGAYATHGAYCARMGNCARAAYAARGGN AGYATHYTNACNAGYACNGTNAGYTAYATHAARAARATGAARAARMGNATGACNGARYTN CARCAYTTYGARGARAARAAYMGNYTNYTNGARGCNAARYTNMGNCARATGAGYATHGCN ATGGGNCARACNAARGTNATGYTNCARTCNACNGGNYTNGAYACNTCNGTNYTNGAYGAR ---------------GTNYTNCARGGNATGACNYTNMGNGCNGTNGTNCCNGCNGCNGCN ACN------ATHACNACNGTNGCNTCNATGYTNCCNACNAGYACNATHACNGARCCNTTY ACNGCNCARATGGARGAYTAYATGATGGAYAAY---AGYCCNGTNGGNGGNGAYCCNATG YTNYTNTCNCARCCNGTNTCNCCNGARCCNGAYGAYCAYYTNCAYGAY---YTNMGNMGN GTNGCNTGGMGNCAYYTNYTNAAYGTNTTYCCNGCNAAYATGTCNGGNMGNGAYMGNTTY GAYTAYYTNAARMGNAARGARGARGARTAYMGNAAYYTNMGNGAYGARTGGMGNGARAAR GTNGCNAGYAAYTCN---YTNGARGARMGNYTNAARAAYYTNCARAAYGCNYTNCARGTN TAYGGNCCNAAYTCNCARGCNTTYYTNGCNGARTCNGTNCARAGYCCNTGGGARMGNGCN GTNGCNGGNAAYAARGTNCCNTAYTAYATHAAYCAYGCNACNGARACNACNCARTGGGAY CAYCCNCARYTNACNAAYYTNATGGAYGCNYTNTCNGARYTNAAYAARATHMGNTTYGCN GCNTAYMGNACNGGNATGAARYTNMGNATGYTNCARAARAARYTNTGYYTNGAYACNGTN ATGYTNGCNATGGCNATGGARGCNTTYGAYAAYCAYGGNYTNMGNGGNMGNAAYGAYAAR YTNATGGAYGTNGGNGARATGATHGARTGYYTNACNACNATHTAYGARGCNGCNGCNAAR GARMGNCCNGARYTNGTNAAYGTNCCNYTNTCNGTNGAYATGACNYTNAGYTGGATHYTN GAYGTNTAYGAYACNGTNMGNAGYGGNAARGTNMGNGTNYTNTCNTTYAARGTNGGNGTN GTNYTNYTNTGYCARGCNCARYTNGARGAYAARTAYMGNTAYATHTTYMGNYTNATHGCN GAYACNAAYGCNTTYGCNGAYCARMGNAARYTNGGNYTNYTNYTNCAYGAYTGYATGCAR ATHCCNMGNCARYTNGGNGARATHGCNTCNTTYGGNGGNAGYAAYATHGARCCNAGYGTN MGNAGYTGYTTYGARAARGCNAAYGGNMGNCCNGARATHGAYGTNAGYCAYTTYCARGAR TGGYTNAARYTNGARCCNCARTCNYTNGTNTGGYTNCCNGTNATGCAYMGNYTNGCNGCN GCNGARACNGCNAARCAYCARGCNAARTGYAAYATHTGYAARGARTTYCCNATHGTNGGN TTYMGNTAYMGNTGYYTNAARTGYTTYAAYTTYGAYGTNTGYCARAGYTGYTTYTTYTCN GGNMGNACNGCNAARAGYCAYAARYTNACNCAYCCNATGCARGARTAYTGYACNACNACN ACNTCNGGNGARGAYGTNMGNGAYTTYTCNAARGTNTTYAARAAYAARTTYMGNTCNAAR MGNCAYTTYAARAARCAYCCNMGNMGNGGNTAYYTNCCNGTNCARTCNGTNYTNGARGGN GAYAGYYTNGARAGYCCNAAYCCNTCNCCNCARCAYAGYATHTCNCARGAYATGCAYTCN MGNYTNGARATGTTYGCNAGYMGNYTNGCNGARGTNGARCARMGNCARTCNGGN---TCN TCNCCNGAYATNGARCAYNNNYTNATHGCNNNNTAYNNNNNNNNNYTNGARGAYGARCAY CAYYTNATHGCNCARTAYTGYTCNAGYYTNAAYGGNGAYCCNTCNTCNCAYGCNYTNAAR AGYCCNATGCARATHATGATGGCNGTNGAYGCNGARCARMGNCAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNMGNTAYYTNAARCARTGGAARAAYAGYAARGARAGYTGGAARTTYAARACNCAY GTNCARACNAARYTNYTNCAYGTNATGTTYGAYCCNAARACNATHAARGAYGCNGAYTTY AAYYTNGCNGTNGARTAYGTNAARAGYATGAARGGNAARTCNMGNGTNACNACNCARGAR CARGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARGAYMGNMGNAARGARAAR CCNTTYYTNTAYCARATHGTNTCNAAYAGYACNAAYGGNATHGAYGTNGAYAARTGGGAY TAYYTNGCNMGNGAYTGYCAYTAYYTNGGNTTYCCNACNAGYTTYGAYAGYAAYMGNTTY ATHATHTAYGCNMGNGTNGTNMGNACNCCNGAYGGNCARCARATHTGYTTYMGNGAYAAR GAYGCNTTYGARGTNTAYGTNATGTAYATGACNMGNTTYMGNYTNCAYMGNCARGCNTAY AARCAYMGNGTNACNCARGCNATHGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNAARMGNGGNCCNCCNCCNCCNAARCCNGTNGARGGNGAYTCN CCNGAYGAY---------AARTCNACNGGNYTNGCNTAYGAYGCNTAYYTNMGNCARGTN GTNGAYGTNYTNGARTCNGAYCCNGAYTTYMGNAARAARYTNGARTCNGCNAAYGTNTCN GAYATHAARAGYGGNAARATHGCNATGCAYYTNGARYTNGTNAAYCAYACNATHMGNACN GCNYTNGAYGARATHAARMGNMGNGARGTNAARMGNYTNCARGAYYTNGCNMGNCARCAR YTNMGNACNATGTCNGAYGTNAARAARATGGARATGCCNGGNCAYYTNGAYYTNMGNAAY CCNCAYAGYTTYGARATGMGNGAYYTNGARAAYYTNATHAARCARACNACNAAYGAYYTN GARGARYTNGAYAARCARMGNAARGARGARTTYAARGARTAYGARATGGARAARGARTTY GARAARCARGARCAYYTNAARCARATGCCNGARGARGARMGNAARAARGARGARGCNMGN YTNGCNGARYTNAARAARAARCAYGCNGAYCAYCCNAARGTNAAYCAYCCNGGNAGYMGN GAYCARTTYGARGARGTNTGGGAYAARGARGAYCAYYTNGARGAYCARGAYTTYAAYCCN AARACNTTYTTYTTYYTNCAYGAYGTNAAYGGNGAYATGATGTGGGAYGTNGARGARGTN GARGGNYTNYTNCARMGNGARYTNGAYAARGTNTAYGAYAAYMGNAAYGCNCCNGARGAR GAYGAYCCNAARGARMGNGARGARGARATGGGNMGNATGMGNGAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNGTNTTYGARYTNGGNAAYAARGTN GGNCARCCNAGYCCNTTYCARGTNYTNMGNGARTGYYTNMGNMGNAAYTTYGGNYTNGGN GAYACNGCNTGYCARGTNAAYACNCARACNYTNAARAAYCARAARTGYGARTTYACNATH ACNGTNGGNAARCAYACNGCNACNGTNACNGCNAARAAYAARMGNGAYGGNAARCARYTN GCNGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MGNTTYTCNGARTTYGARATHAARYTNCCNGAYGTNGTNYTNCCNGGNGTNYTN YTNYTNGGNGARAARCCNCCNCCNGARCCNGARAAYYTNCARYTNGCNGTNCAYCAYGGN CCNTTYGARGARATHGTNGCNATGGCNACNATHGAYTTYCARGAYATHAARGARYTNAGY YTNGARACNYTNTAYYTNCCNGCNCCNCARGGNGAYGARGARGTN---ACNATGMGNTCN MGNCCNGGNTCNGTNAGYGTNATGTCNACNYTNGAYTCNGARTCNYTNTCNGAYTCNATG GAYATHCCN---YTNCCNGAYGAYCCNACNGAYCAY------------YTNGCNCARTCN ACNCCNMGNGAYGARGCNGTNMGNGGNTTYGARCCNATHCCNTTYCCNYTNTAYTCNYTN CAYGCNGGNAARTCNGAYGCNGTNCAYATGCCNTGYGGNACNGTNCCNYTNYTNYTNTAY TGGGGNYTNMGNCCNMGNCCNYTNACNTTYAAYMGNCARACNGGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYCCN---AAYACNCARTAYGTNGGNAARACNTTY TAYATGGAYGGN---GGNGAYTGYAAYGGNCCNATHMGNGARYTNTAYGGNAAYAARGCN GTNATGAARGGNTTYGARAAYTCNGGNGTNAARYTNCCNMGNCARTCNTGYACNATHACN YTNAARAGYGARGGNCARTTYGAYGGNATGGTNYTNYTNGTNMGNGTNGTNTCNGCNGAY ATHMGNGAYTGYTAYACNCARTTYTCNATHTTYGAYGGNTCNTCNAGYGGNYTNYTNMGN MGNTAYGAYTGYAAYACNCARGAYTTYCARAAYGAYMGNYTNATGYTNACNTCNGGNGAY ATGGTNACNTTYATHYTNTCNAARCARAAYCCNAAYGTNTTYAAYTTYGAYATHGARGTN CAYGTNGARCCNAARMGNAARGGNACNGAYCCNGGNTAYGARAAYAAYTGGAAYACNGAY TTYTTYTTYGAYAARTTYTCNCARGCNATHATHGTNGGNATGATHTGYAGYYTNTAYGGN ACNACNATHATHGTNGCNATHGTNATGACNATHTGYTGYTTYMGNMGNTTYAARGGNYTN CAYMGNGARTGGGARACNCAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GAYYTNYTNGARTGYCCNATHTGYAARCARCAYACNCCNYTNCCNGCNGARGGNGTNMGN GGNYTNYTNTGYGAYAGYGTNACNGARGAYATGYTNAARGCNTCNTCNTCNGARGARAAR ---ATHGGNTGYACNAGYTGYAARGCNGGNGARTGYGCNGTNGCNMGNTGYAARACNTGY GARAAYYTNYTNTGYGAYAGYTGYAAYAAYGCNCAYMGNAGYATHMGNATHTTYGARAGY CAYAARGTNGTNACNTTYGARGARATGGCNCARGARGGNGARGAYATHACNAARYTNMGN AARCCNGTNTTYTGYGARCARCAYTCNTCNGARACNATHAARTTYTTYTGYAAYACNTGY YTNGTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GCNCAY CAYMGNGTNTGGTTYAARACNAAYGGNTAYATH--------------------------- ---------------------------------------------------CCNTCNGAR GAYAARMGNTTYAARAARACNGCNGAYGCNYTNCARAARTCNGGNYTNTGGGAYATHGCN ATGAARACNGGNGCNYTNATGAARAARAAYMGNGARYTNCARAARGARYTNGARTCNTTY MGNATGGARGCNYTNGCNYTNYTNMGNAGYGTNATHAARAAYCCNGAYAAYAARCARTTY GTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGGCNAGYGTNAGYGTNMGNCAY YTNYTNYTNACNYTNCARGCNYTNGCNTGYTCNGCNAGYGGNCCNCCNACNATHGCNGGN AARATHGARCAYMGNCAYATHGCNAARMGNGGNAARAGYACNMGNYTNYTNTGYCCNGTN GARGCNCCNCCNTCNYTNACNCARTGGAARAARGAYGGNCARTCNATHACNGAYGGNTGG ACNMGNTTYAARGTNTCNGCNGARGGNGAYYTNMGNATHAARGAYGTNCAYATGGARGAY GCNGGNCARTAYYTNTGYMGNGCNGTNAAYGGNTTYGGNGTNATHAAYATHAAYTAYACN GTNATHGTNYTNGAYGARGARAARGGNATHGTNCARCARGCNGAYGARCARTTYGCNCAR TCNCCNGGNGARGAYYTNACNAARCARGGNGCNGGNCCNTCNTTYGTNGARYTNGARAAR ATGCARCARAAYATGAAYCCNGTNAARCCNACNGGNAGYACNGTNMGNYTNAARTGYMGN GCNGAYGGNAAYCCNMGNCCNCARGTNACNTGGTTYAARGAYACNCARCCNTAYCAYCAR MGNMGNCCNCAYTGGATHYTNAARYTNCAYAARGTN------GTNGARAGYGCNMGNCAY ACNMGNGTNGTNTCNAAYMGNCCNGGNGCNGTNAAYTTY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNGTNYTNTCNYTNYTNATHATHATHGGNTAYYTNTGYTAYAARMGNAAR------ ------AARGAYMGNAARMGNGCNCCNAAYGTNGTNTAYYTNCCNGCNCCNAAYTCNGAY ACNCAYCCNATHTAYCARGARGTNTAYGAYGARMGNAAYYTNAAYAGYGGNTGYTCNTTY CCNCCNTCNYTNCCNCCNMGNTAYACN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARGARAGYGGNACNATGGAR AARAARCCNATHACNMGN------CARGCNTCNTCNTCNTCNCARTCNAAYGGNGTNATH AGYGARAARAARAGYGAYTAYGTNTCNAAYAARAAYGGNMGNCAYMGNMGNAARGGNAAY GGNTCNAARACNCARGARAGYYTNTCNACNTCN------------MGNACNACNGCNCAR AARTGG---MGNAAYGGNGGNGAYAARMGNCCNMGNCARMGNAGYTAYATHGARAGYMGN CARMGNGARGARGTNGCNGAYCARYTNGARGCNAAYGAYGTNTTYGARTCNMGNTCNMGN AARGGNAAYGCNAAYCAYYTNYTNAAYTTYTAYTTYYTNCCNAAYGARGGNTGGGGNMGN GGNGCNGGNCAR------------------AGYTAYGTNCAYMGNCAY------TAYMGN AARYTNCCNMGNTAYAAYAARGARMGNTTYYTNCARGCNAGYTGYCARTTYGTNGTNMGN GAYACNGGNGAYTAYATGAARCARGCNATHGAYCCNGAYGCNYTNGTNGAYTGGAAYAGY ATHGARYTNGTNMGNAAYTTYAGYACNGARCARATHMGNTGYCCNATHTGYYTNGARATH CCNTAYGCNGGNAARATHACNAARTGYGGNCAYATHTTYTGYTGGGCNTGYATHYTNCAY TAYYTNAARYTNTCNGARAARGAYTAYAAYMGNTGYCCNYTNTGYTAYGAYGCNGTNAGY GARGARCAYYTNAARAGYGTNCARTCNYTNGARYTNCCNGAYYTNACNGTNGGNGARCAR ATHACNATGCARYTNATGMGNMGNGAYAARGGNAGYATGCAYGTNAGYCCNAARTCNYTN TGGGARGAYACNGGNGGNATHCCNYTNTAYGARGGNAGYGGNGARMGNACNAARTTYAAY AARYTNYTNATHGCNTCNGTNGCNCARATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARATHGGNCARCCNTGY YTNCCNCCNGARGCNGCNACNGCNACNAARATGCARYTNTCNAGYTGYTAYCCNYTNCAR GTNGAYTCNGTNGTNGAYATGGGNTTYTCNYTNTAYGGNCARYTNCARAARGTNACNGGN ATHGTNAAYAAYAAYGTNGAYGTNACN---GCNGAYAARCCNTCNCARCCNGCNTGGGAR TCN------------------AARCCNAGYMGNATGYTNATGATGGARATGACNGAYGGN AGYACNAAYATHMGNGCNATGGARTAYMGNCCNATHAARTCNYTNAAYTCNYTNYTNCCN AGYGGNACNAARGTNAARGTNTCNGGNYTNGTNATGTGYMGNTGYGGNGTNYTNYTNYTN GARCCNGAYAGYGTNGARGTNYTNGGNGGNGARGTNGAYGTNYTNATGGARAARAAYACN CARGARACNATGYTNTCNGCNGCNATGGARMGNAAYMGN--------------------- ------------------------------------------------AAYAAYCCNGCN YTNGTNGARGGNGTNGTNAAYGARGARYTNGTNATHAARAAYAARCCNCCNACNGGNCCN TCNAGYATGGTNATHTTYTAYACNTGGATGATHYTNGTNGTNYTNATHACNYTNGTNGGN GTNTCNACNTGYCARAAYMGNTGYCAYGGNCARMGNAARAAYGGNTAYGGNACNMGNCCN ACN---GARGARAARMGNMGNYTNATHACNAAYGARTTYGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNATGATH MGNCAYYTNTCNYTNMGNAAYTGYGTNTGGGTNGGNAARGAYAGYYTNGTNTCNTTYATH TGYAAYGGNMGN------ACNYTNGARTTYATHGAYYTNTCNGGNTGYTGGAAYYTNGAY GAYGARATHGTNGARCARYTNGTNATGTAYTGYAARGGNATHMGNCAYYTNYTNYTNAGY AAYATHTAYGGNYTNACNGAYMGNACNGTNGTNGCNGTNGCNCAYATGTGYCCNGAYYTN AARACNYTNAAYATHTCNGGNTGYTGGMGNATHACNGAYTCNTCNGTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNAAYCCNATGGCNCARGTNCCNTCNYTNAARATHGAYGGNATH GTNYTNACNCARTCNATHCCNATHATHGARTAYYTNGARGARMGNAAYCCNGAYCCNCCN YTNYTNCCNAARGAYYTNGCNGGNMGNGCNAARGTNMGNGCNATGGCNGARATHATHAAY AGYGGNATHCARCCNYTNCARAAYYTNCAYGTNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGTCNGAYAARYTNGARACNAARGTNATHCARGTNACNAAY GTNGCNCCNGGNGCNTCNMGNGARCARATHAARACNYTNTTYAGYTAYYTNGGNMGNGTN AARGAYATHAARATGTAYCCNCCNGARAAYAGYGAY---MGNCARGTNTCNTCNMGNGTN TGYTAYYTNGARTAYGARGAYGCNGARTCNGCNGGNGTNGCNYTNCAYYTNACNAAYACN GTNTTYATHGAYMGNGCNYTNATHGTNGTNCCNGTNATGGAYGGNAARATHCCNGAYGAR AAYACNGCNYTNCARYTNACNCCNCARGCNGTNGCNGGNATGYTNCCNGGNCARCCNTCN TGGCCNAGYAAYGTNGTNAGYCARATHACNGGNACNGGNCCNAAYCARGTNGTNACNACN TAYGAYCCNMGNYTNAAYTCNYTNGGNYTNCCNCARTAYCCNCCNYTNCCNGCNACNACN GAYCCNACNAARATHGARGARATHMGNMGNACNGTNTAYGTNTCNGAYYTNGAYCCNAAR ACNACNACNGARGCNYTNYTNAAYTTYTTYTCNCARGTNGGNGARATHAARTAYGTNTGY ATGGCNGGNGARCARACNGCNGCNGTNMGNGGNGCNTAYATHGARTTYACNGAYCARMGN TCNGTNGCNACNGCNYTNACNTAYAAYAARGTNGARTTYCARGGNMGNTCNATHAGYGTN CARCAYGCNMGNACNAGYATHATHAARCCNYTNTCNAARGCNGARGCNTCNCARMGNGAR ATHGARGARGCNATGAARAARGTNAARGARGCNCARAARYTNATHTCNGCNGCNAGYGAY ------------------------------------------------------------ ------------------AARTCNMGNMGNAGYMGNTCNMGNTCNTTYAGY------MGN AARMGNTCNMGNTCNMGNTCNMGNCAYMGNTCNMGNTCNMGNTCNMGNMGNTCNMGNTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CARTAYGAYGAYCCNACNGGNATGYTNGTNCARCARAGYAARCARGCNACNTAY GARAAYTTYAARACNACNGTNCARMGNTCNYTNGGNAAYGAYGTNAGYTGGGAYACNYTN GCNTTYYTNTTYTAYACNACNAARGGNGTNGTNTCNGCNGTNGGNAARGGNACNTCNYTN GCNTCNCARGCNAARGAYYTNACNYTNCARTAYGTNAGYGAYAARTTYGCNGGNTGGATH ATGGAYCARGGNGGNTTYGAYAGYATGYTNAGYGGNAGYGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CCNGTNCCNCCNCCNTGYGARGARACN---------------TAYATHGCNATGTTYGAY TTYACNCCNGARGARGARACNGAYYTNTGYYTNGTNMGNGGNGAYAARTAYCARATHYTN AARAARACNGAYGARAAYTGGTGGTTYGCNMGNGAYAGYACNGGNCAYGARGGNTAYGTN CCNTCNAAYTAYYTNAARATGAAYTGYGGNYTNGARATHTAYGARTGGTAYTAYAARGAR TGYTCNMGNGARACNGCNAARAAYATHYTNATGAARGAYMGNMGNGARGGNTGYTTYYTN GTNMGNGAYTCNATHAGYAGYCCNGGNGAYTAYACNYTNTCNATHTGGACNYTNGARAAY GARGGNAAYATHMGNCAYTAYCARATHAARMGNAAYACNGARGGNYTNTTYTAYATHGTN GAYACNCAYGCNTTYAGYAGYATHCCNGAYYTNGTNCAYTAYCAYAARCAYAAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATHATHYTNTCNGCNGTNTTYTGYGCNTGYAGYAGYCAYYTNTGYATGYTNAGYCCNCCN CARMGNGGNTCNATGAGYGGNATHAAYAARCCNGGNGCNAAYGAYTGYTTYYTNACNGAR GGNTCNTGYGGNGGNMGNCCNGARGGNAARGCNAARGTNTTYYTNCCNGCNGGNGARAAY TTYACNGTNACNYTNCARAARAAYYTNGAYCAYTTYTAYAARACNTCNCCNGGNTAYTTY TCNYTNTCNYTNMGNAAYTCNAAYCARACNTTYCARGARYTNCARMGNATGACNGAYACN TCNGAYCCNGCNYTNACNYTNTAYGTNYTNAAYGTNACNATHCCNMGNGTNGARGGNCCN GTNATHTTYCARTCNCARTAYGTNACNAARAAYCCNCARGCNCCNGCNGCNTTYTAYCAR TGYGCNGAYATHCAYGTNYTNCCNMGNMGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNACNAARGAYMGNGCNAARTAYGCN CARATHYTNGARGGNYTNATHTCNCARGGNYTNTAYCARYTNYTNGARCCNACNATHACN YTNMGNTGYMGNMGNGARGAYYTNGAYATHTGYAARTCNGTNTGYGARAARAGYAARGAR GCNTAYAARAARGCNACNGGNGGNMGN---GAYGTNGARATHAARTTYGAYACNGAYAAY TTYYTNGGNCCNGARGTNTCNGGNGGNGTNGARYTNYTNTGYMGNGGNGGNAARATHAAR GTNGTNAAYACNYTNGARAGYMGNYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNCARGARGARMGNTTYTTYGCNGTNAARCCNTCNAARGAYGCN YTNGAYGCNAGYAAYACNTTYTCNCAYGAYAAYATHGTNCARYTNGTNAARAAYACNACN GAYACNTGYAARYTNGAYGTNYTNTTYAGYAAYAARAARAARTAYACNTAYCARTTYGAR AAYGCNGTNAARMGNGARAGYTTYTGYYTNCARATHMGNCARATGAARTCNATHCAYTCN CARGARCARGAYGTNGAYAAYATHTCNGTNTTYGTNGGNACNTGGAAYATGGGNAARTCN GCNCCNCARGARAGYYTNAARTAYCCNATHGTNTAYATHCARMGNATHCARTCNTTYAGY GCNTGYCAYMGNYTNCAYAGYCCNTTYYTNTCNGAYGAYGARAAYGCNAARYTNTAYGGN AARTGYAAYCAYYTNCAYGGNCAYGGNCAYAAYTAYAARGTNGARGTNACNATHAARGGN CCNGTNGAYCCNATHACNGGNYTNGTNATHAAYATHGTNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TCNGGNGTNGGNCARACNGCNAGY GTNYTNCARCCNCARCARACNGGNACNGGNACNACNAAYGGNACNCARGTNAGYAAYGTN AAYGCNTCNGGNYTNCCNCARATGYTNTTYYTNAAYCARGTNACNATHAAYGGNCARACN TCNTTYGTNYTNGTNGAYGCNAAYAAYAARCCNGTNCARYTNCCNCARGGNATHCARGTN ATHAAYYTNCCNTCNCCNAGYATH---GGNCARCARYTNCCNATGCCNGGNTCNGARACN GGNGAYGARCCNYTNTAYGTNAAYGCNAARCARTAYCAYMGNATHYTNAARMGNMGNCAR GCNMGNGCNAARYTNGARGCNYTNGGNAARYTNCCNAARGARMGNCARAARTAYYTNTAY GARTCNMGNCAYAARCAYGCNYTNAAYMGNCARMGNGGNTCNGGNGGNATHTTYACNGGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GAYGGNAARGTNGARMGNGAYTCNGAYGGNAARGARATHMGNTAYCCNGTNYTNYTNTCN GCNMGNGARAARYTNATHGCNMGNAAYGTNATHCARGTNTTYAARCARAAYGTNTGYGGN TTYGAYYTNYTNMGNGCNAGYGGNCARTGYTTYGTNTGYGAYGGNAAYGGNTTYAGYTTY GTNAARACNTCNAGYAARTAYTAYGAYGAYTGYGCNAARATHYTNGGNACNYTNGTNYTN MGNGCNGTNTGYCCNCARYTNCARATHCCNTGYCCNYTNGGNACNGCNCCNGARGAYATH CCNGTNGTNCARACNACNTCNGGNTCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARTCNTCNGARGAYGTNACNATH AAYGGNGTNACNATHCCNMGNGGNACNGCNATHTAYATHGCNATHGAYTCNGTNAGYTAY GAYCCNGTNCAYTTYCCNGARCCNGARAARTTYAAYCCNGARMGNTTYGARGARCCNAAR TCN---------GTNACNTTYYTNCCNTTYGGNTTYGGNCCNMGNATGTGYYTNGGNATG MGNYTNGCNCARATHGARYTNAARATHGCNYTNGTNCAYGCNYTNMGNMGNGTNAARATH YTNGARACNACNAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GCNAGYACNCAYAGYACN YTNCARGCNCARGGNAARACNAGYCARATGCCNAARAARTAYAARCAYCAYAARCAY--- TCNTCNTCNTCNTCNTCNAGYTCNTCNAGYGARTCNTCNGAYGAYGARTGGMGNCAYYTN CCNAARCAYGARAARAARATGMGNAARAARTGGAARAARAAYATGMGNAARGGNAARATH CCNCAYGGNCARGTNGCNCCNTGGCAYGGNGGNCCNGCNTGGTAYCCNCCNACNAARCCN GGNAARGTNGGNAARAARGGNAARGTNAARGGNTAYCCNAGYAGYGGNTAYCCNCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AGYGARYTNGAYGARACNAAYGAYYTNATGCAYATGGTNGARGARGAY MGNGTNACNYTNTCNACNACNYTNGAYCARCARMGNCARCARYTNCARAAYYTNGCNGAR GARAARCARAAYATHYTNAARCARYTNGARGAYGGNTTYGCNACNCARTCNGCNYTNAAY GCNGARAAYATGTCNYTNTCNCARACNACNGARCARYTNAARCARGCNYTNGCNGARGTN GARAGYMGNACNAGYTCNGTNYTNGARGARAARAGYGCNGCNGARYTNMGNYTNMGNGAY AAYCARGARMGNYTNGAYCARYTNGARGARGARAARGTNACNATHTCNGARCAYGCNCAY GARYTNCARTCNACNATHCARGAYYTNAARGCNCARAARGARATGACNGARAAYGARYTN AARGARGARATHAARGCNMGNATGTCNGCNGARGARMGNYTNMGNGAYGCNGARAARTCN YTNAAYAAYYTNGAYCAYGCNGTNCARACNCARAGYCAYAAYATHGARCARGARGTNAAR GARGARATGACNGTNAGYGTNMGNAARYTNAARGARTTYTTYGARGAYYTNGCNACNGAR GCNAARATHTCNTCNGARCARCCNYTNATHATHMGNAAYGGNTTYACNGCNMGNAARACN YTNGCNMGNMGNGCNAARACNATHMGNTAYGARAGYAARAARMGNTCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GGNGARAGYGTNTGYMGN TGYTGYGARTGGTGYTTYGGNYTNMGNTGYTGYMGNGTNTGYGCNCARAGYTCNYTNAAR MGNYTNYTNMGNYTNACNGAYGTNTGGCARACNGTNATGYTNTAYACNGTNTTYTCNTTY ACNACNATHGCNYTNGARGAYATHTTYCCNGTNTTYGCNTCNACNMGNATGGAYTAYGGN GGNYTNGGNTTYGAYACNGAYGAYATHGGNATHGCNYTNGGNATHGTNACNYTNCCNYTN YTNYTNATGCARGTNAARYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNAGYMGNGGNGARAAR GAYGAYGAYGARGAYGARGARGARGTNMGNGARGAYCCNAARATHAARMGNGARYTNGAR GARATHTCNAARATHAARGAYGARTCNGGNATHGGNMGNGTNATHTAYMGNGARYTNGAR GGNYTNAARGCNAARCCNGCNCARCCNYTNGAYCCNTGGAARGCNTCNMGNGCNCCNAGY GCNAARTTYGARCCNMGNTAYMGNACNMGNTTYCARTCNCCNATGTTYGCNTCNCCNTCN MGNTTYYTNGAYMGNCCNMGNTAYGCNTGGGAYGAYAGYGAYATHMGNGCNTAYMGNTCN TCNTCNGCNYTNACNAAYTTYCCNACNCCNMGNCCNGGNTAYGGNCCNTCNTAYATHGCN CCNMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARYTNYTNAAYTTYAGYATHATHMGNGCNGCN TTYGAYGGNGAYATHTTYGARAARAAYTAYGAYAGYAAR---GCNACNAAYATHTCNTTY GGNYTNGAYGGNGAYGGNTAYTAYGTNAARAARAAYTAYACNGCNTGGACNGCNAGYGTN GGNTAYGGNGAYGCNCCNGARGAYACNGTNTCNATHATGGTNATHATHACNATHGCNTGY GGNYTNGGNYTNCCNGCNGTNATHGTNYTNGCNGGNGCNGTNTAYACNGTNGTNMGNAAR ATHMGNMGNAGYGGNGGNAAYAAYTAYCARCCNGTN---GGNGGNGGNGTNGTNTCNTCN AGYTAYCCNGARGTNAAYATHAARTTYATHGARTTYGTNYTNTCNATHTTYGCNTTYGCN ACNACNACNAGYCCNGAYAGYAGYACNAGYTTYCARGTN---GAYTGYAARAAYGGNACN GARCARAARGTN---------------GTNAARTTYAGYTAYAGYTAYCCNTAYGAYYTN GARGAYGTNTGYTTYAARACNCCNGTNTGYGARGAYACN---AARACN---------GGN GCNTTYTGYYTNYTNTCNGGNTCNCARTCNTCNGCNCARTTYTAYGTNTTYGTNGGNGTN ATHGTNTTYYTNTAYTGYATHGGNGCNATHATHYTNTAYGTNTTYTTYGAYGAYYTNTAY MGNMGNAAYAAYMGNGCNGTNATHGTNGAYTTYGTNGTNTCNGTNGTNYTNACNYTNYTN TGGATHATHGGNTCNTCNGCNTGGGCNGCNGGNYTNTCNGAYGTNAARATGTAYACNGAY CCNTAYGAYGGNAGYATHTTYAAYAARAAYTTYCCNGARTGYYTNGAY---AARACNAAR TGYAARACNATGGAYACNGGNAAYTTYGCNAGYYTNAAYGTNTCNATHATHTTYGGNTTY YTNAAYTTYGTNGTNTGGYTNGGNAAYYTNTGGTTYYTNTAYAARGARACNCCNTGGTTY AARGTNCARTCNAARCCNCCNACNGCNCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CCNGGNTAYTGGCCN CCNGGNGAYAAYAGYAAYAGYAAYTCNTCNCARGTNTCNCCNCCNMGNGAYCAY------ ------TTYCAYCAYCAYCAYCAYCCNCAYCAYCAYCAYCAYCCNCAYCAYGGNATGATH GCNCAYGCNGGNMGNCCN------ATGCAYCAYMGNGAYGCNGTNCAYGGNGAYGAYTCN GGNYTNGAYGCNGCNAARMGNAARCARYTNCCNGCNTGGATHMGNGARGGNYTNGARAAR ATGGARMGNGARAARAARAARGARGARGAYMGNYTNMGNGCNCARGCNGARAARGARGCN ATGYTNAARGCNGCNGARGARGGNAGYGGNGCNYTNGGNAARGARGARGARGARAARAAY GAYGGNGARCCNAARGTNCCNAARAARAGYMGNTTYGAYTCNGAYGARGAYGAY------ ---GAYGAYGGNAARCARAARGAYGARGAYGAYGTNGAY---GAYGCNTCNGAYAAYGAR AARGCNMGNTCNMGNTCNMGNTCNCARGARAARGAR---------------TCNMGNMGN MGNAGYCCNTCNCCNGCNAARCCNATGACNGARGARGARAARATGATGGARATGATGGTN AARGTNAARCARTGGATGACNGARATHYTNYTNGAYGTNACNAGYAARGARATGMGNGAR GTNGCNMGNGARGTNTTYAGYAARGCNAARAARAARGCNYTNAARGGNMGNGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTAYAAYGGNATHGGNYTNACNACN CCNMGNGGNAGYGGNACNAAYGGNTAYGTNCARMGNAAYYTNTCNAAYGTNAAR---MGN AARGARMGNGTNGAYTAYAARTCNGARGARGARATHGCNAARYTNGARCARTCNYTNGTN AARCARCCNAAYCARGARATHYTNGCNCAYGAYMGNAARMGNMGNGTNGARYTNAARTGY GTNGARATGCARGTNYTNATGGARGARCARGGNTAYCCNGCNGAYGARATHAGYCARAAR GTNGCNGCNTTYMGNAARATGYTNATGGARAARATGGAYYTNACNGAYGCNACNCCNGTN GARMGNGAYCAYAAYGGNMGNCCNYTNGCNMGNGARACNCAYCARYTNGCNGARGCNAAY GCNGARAARAAYGCNMGNYTNAARGAYGCNTTYGGNYTNGGNGAYTAYGTNGARGGNAGY GCNTTYGAYCCNGARCARAARGCNAARCARGARGCNGCNMGNGCNGTNGCNATGGCNCAR AARAARTAYAGYACNGTNCAYAGYTCNGARTCNGARGGNGARGARGGNACNTCNCCNCCN GCNAARAARAARAARAARAARTCNAAYMGNCAY---AGYAGYMGNTCNCCNGARMGN--- MGNGARAARAARAARAARAGYAARAARCAY---MGNCAYGAYMGNGAYATGAAYCAYYTN CAYYTNGARAAYAARCARYTNMGNYTNGAYYTNCARTCNGARCARGAYYTNGTNATHCAR YTNMGNAARMGNYTNAAYCARGCNGARAARCARAARYTNGARGGNACNACNAARGCNAAY GCNGARATHTCNTCNYTNGARAGYCARGTNGCNAARYTNMGNTCNCARATHGARAARGGN GARGCNGCNMGNCAYAAYYTNGARTAYGARYTNACNAARGCNMGNMGNGARYTNAAYCAR TGYAARCARGCNAGYAARGARMGNGARGCNYTNYTNATGGARGGNAAYGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNACNATHGAYAAYCAYGARTAYTAYACNTCN CAR---GTNCARGAYAAYGTNGTNGAYAARCAYTGGGTNGARYTNGARACNGCNGTNCAR CAYACNACNYTNTCNMGNAGYCAYMGNATGGCNGCNGTNATHCARYTNAARTTYCARTTY CCNTTYTAYGGNCAYTTYGTNACNAAYGTNACNGTNGCNACNGGNGGNTTYATHTAYATG AGYCCNTTYYTNCAYCARTGGYTNACNGCNACNCARTAYATHGCNCCNYTNATGGCNAAY TTYGAYYTNGGNYTNAGYACNGAYTCNAAYATHTAYTAYCARAGYATGGARGAYAAYTTY ACNGTNGARTGGAARGAYGTNATGYTNAARGAYCARAAYGARAGYGGNAARTTYCAYTTY CARACNACNYTNTTYMGNGGNGGNGAYATHACNTTYTCNTAYAARAARYTNCCNYTNCCN GTNCARAAYATHTCNAGYGAYAAYCAYCCNGTNAARATHGGNGTNTCNGAYGCNTTYTAY ATHGAYACNTAYCCNTCNMGNTAYAAYGTNAARAARMGNACNATHTTYGARTAYCAYAAR GTNGAYGTNACNTCNTCNGCNATHMGNCARGGNAGYGTNATHATGYTNAARCCNYTNCCN ACNTGYAAYYTNYTNACNGAYTGYCARAGYTGYGTNAGYCAYATGAAYGTNAARTTYGAR TGYMGNTGGTGYAAYACNATHGGNMGNTGYTCNGAYGGNTGGGAYTGGTAYMGNCARCAY TGGACNACNTTYAAYTGYGCNGCNACNTCNACNGAYGTNATGGCNGARTGYTCNAGYGCN CCNTCNACNAARMGNCCNGGNAGYGCNACNCCNCARACNTCNACNACNGAYATGTTYGGN TGYGTNGGNGAYTCNTGYAARGAYAARGAYTCNGAYACNCCNGTNGCNGTNATHGTNATH GTNACNYTNGCNGTNGTNGTNYTNGTNGGNYTNTTYGCNGCNTGGGTNTTYTAYGCNTAY ACNCAYCCNACNTCNAARTCNGGNATGTGGYTNATGGARCAYMGNCCNAGYCARATGAAR GCNAARATHAARTTYTGGAARAGYAGYACNCCNAAYGGNGCNAARTAYGCNGTNGARACN GAYGCNATHCARACNGTNMGNYTNAAYTCNAARYTNGCNGARGARYTNGGNTCNGCNMGN AARGARATHGAYGTNYTNAARGGNMGNYTNAARGARYTNGARATGAAYCARYTNGCNMGN GARTGYACNCARGARMGNTAYGGNYTNCAYMGNCAYACNAARATHAAYGGNYTNTCNGCN MGNCAYCAYAAYMGNGGNCCNCCNCCNACNGGNAGYYTNATGTGYGCNGARCCNYTNTAY GGNTGYAARTGYTCNGCNTGYGARGARGCNATGGGNGGNGARGGNCAYGCNGARGTNAGY GCNAGYYTNAAYCARGARYTNCARAARTTYCCNATHAAYTCNAAYYTNYTNGTNCARYTN GGNGAYCAYGTNGTNACNAARGGNGARMGNACNGGNMGNATHMGNTAYATHGGNCAYYTN GAYCAYATHGGNCAYCCNAAYATGATGTTYGTNGGNYTNGARYTNGAYGCNCCNGTNGGN MGNCAYGAYGGNTTYTTYAAYMGNAARMGNTAYTTYTTYTGYCARMGNGAYCAYGGNATH TTYYTNCCNYTNAAYGAYATHATHTGYAARGTNCAYACNAARACNTCNAGY--------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------TTYYTNTAYGGNTAYGCNACNGTNCCNGGNTTYGTNTCNTAYMGN AGYMGNTCNYTNGGNACNTGGTAYATHGAYGCNYTNACNAARGTNYTNGAYCARCAYGCN MGNAGYAARGAYYTNYTNACNATGYTNACNYTNYTNAAYAARGAYGTNAGYMGNGAYTTY CAYGAYCCNAAYAAYYTNGAYGARGARAGYMGNCCNYTNAARCARGTNCCNGCNCCNCAR TTYACNYTNYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GGNMGNGAYGTNGCNGTNGTN TCNTGYGTNYTN---GAYTCNCARTAYTCNGARACNGARGCNGARGCNATGATHGARGGN YTNMGNMGNGAYGTNMGNTCNACNGARAAYTCNTTYGCNYTNATGTAYAGYTGYGTNGGN MGNGGNACNAAYCAYTAY---CARCARGAYGTNGARACNMGNYTNTTYAARAARTTYTTY CCNCARACNCCNGTNATGGGNTTYTTYGGNTTYGGNGARYTNGGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYATGCARAARTTYCARAARATHAAYCAYTTYCCNGGNATGAAYGAR ATHTGYMGNAARGAYATGYTNGCNMGNAAYYTNAAYMGNATGYTNAARATGTTYCCNAAR GARTAYAGYGTNTTYCCNAARACNTGGTGYYTNCCNGCNGAYTAYGGNGAYTTYCARGCN TAYACNMGNCARAARAARAAYAARACNTAYATHYTNAARCCNGARTCNGGNTGYCARGGN MGNGGNATHTGGGTNACNAARAAYCCNAARGAYATHAARCCNCAYGARCAYATGATHTGY CARGTNTAYACNAAYAARCCNTTYYTNATHGAYGGNTTYAARTTYGAYYTNMGNATHTAY ACNYTNATHACNTCNTGYGAYCCNYTNMGNATHTTYGTNTTYAARGAYGGNYTNGCNMGN TTYGCNACNAAYMGNTAYTGYGARCCNTCNCAYAGYAAYACNGAYAAYGTNTAYATGCAY YTNACNAAYTAYGCNATHAAYAARCAYAGYGARGAYTTYGTNMGNGAYGAYGARGCNGGN AGYAARMGNMGNATHAGYACNATHAAYAARTAYYTNCARCARAARGGNTAYGAYGTNGAY AARYTNTGGGCNGAYATHGAYGAYGTNATHATHAARACNGTNATHTCNGCNCAYTCNGTN YTNAARCAYAAYTAYMGNACNTGYTTYCCNAAYCAYGTNAARGGNAGYGCNTGYTTYGAR ATHYTNGGNATGGAYATHYTNYTNGAYAARAARYTNAARCCNTAYATHYTNGARGTNAAY CAYTCNCCNAGYTTYTCNACNGAYGCNACNYTNGAYMGNGARATHAARGGNACNYTNATH TGGGAYACNYTNMGNYTNATHAAYTTYGGNGCNATGGAYMGNMGNAARTGYATHGARGAR GARAARAARMGNATHAARGAYMGNYTNYTNGGNAARTAYTCNAARAARGARACNMGNGAR GARYTNGARGCNGCNCARYTNYTNTAYATHGARCARYTNGARGGNTAYGARAAYAGYCAY ATGGGNAAYTTYMGNMGNATHTAYCCNATHCCNGGNAGYGAYAARTAYGARAARTAYTTY CAYAGYAGYGGNACNYTNTTYCARGARACNGCNGCNTTYAARGCNMGNCARGARYTNGCN MGNCARCARMGNGARGARYTNYTNMGNAARAARGARAARAAYGARATGATGYTNMGNGGN AAR---MGNMGNGAYGGNGCNMGNCCNGARAGYCCNGGNMGNMGNAARMGNATGGTNMGN MGNCCNACNYTNCCNTTYCARAAYYTNATHCARMGNTCNYTN------GARGARGARGTN GCNATHGAYACNYTNAARCCNCARGAYATHGAYGARGAYGAYGARYTNGARMGNATHTCN GGNYTNYTNCARMGNGAYAAYYTNGTNMGNGGNYTNGGNATHGTNGARCAYGTNTAYMGN YTNYTNCAYTGYACNCCNGGNACNATGGGNATHGTNMGNCCNGAYCARMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AAYATGYTNATHTCNTAYMGN GARATHCARGAYTAYAAYGCNATGGTNAARYTNGTNGARGARGTNAGYCAYATHCCNAGY GTNAARGTNGAYTCNAAYGTNGGNATHCARAAYYTNTAYGCNTTYGCNYTNAAYMGNAAY GGNAAYMGNGAYAARGCNYTNGAYGTNATHYTNAARGCNATHGAYAARGCNGARACNCCN GTNCCNGAYATGATHTGYYTNTGYGGNMGNATHTAYAARGAYAARTTYGTNGAYTCNGAY TAYAGYGAYAARGARGCNYTNCARAAYGCNATHAGYTGGTAYMGNAARGGNTTYGARGTN CARCCNAAYGARTAYGCNGGNATHAAYYTNGCNACNYTNYTNGTNATHTCNGGNAARGAY TTYTCNTCNTGYTCNGARYTNCARMGNATHGGNATHACNYTNAAYAAYYTNATHGGNAAR AARGGNAGYYTNACNYTNYTNACNAAYTAYTGGGAYGTNGCNACNTTYTTYGARATHAGY GTNYTNGCNGARGAYTAYAAYAARGCNGTNCARGCNGCNGAYTGYATGGARGAYCARGAR AARACNGTNMGNYTNTGGCAYGTNTGGCARGAYCCNAARGAYCAYMGNCCNAAYGAYTGG ACNTTYCCNGCNGAYACNATHAARMGNGTNAGYYTNTAYAARMGNGAYTCNMGNGCNATH TTYYTNTAYATH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TGYAAYATHTGYYTNAGYGAYTAYGARMGNGGNNNNCARAARMGN AARYTNAAYTGYYTNCAYGARTTYCAYAARTCNTGYATHGAYCARTGGYTNGTNMGNAAY GCNACNTGYCCNATHTGYMGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GARGCNMGNAGYMGN GGNGARYTNTTYGARTGYCAYTGYTGYTAYGARGAYGCNTGYYTNTTYGARGARATGGCN GCNTGYGCNGAYGGNCAYYTNTTYTGYMGNACNTGYATHYTNMGNTCNACNGARGCNGCN TTYGGNGARATGAARACNMGNTTYCCNTGYYTNGGNGARGAYTGYGAYCARGARATHCCN YTNTCNACNYTNCARGCNATHGTNTCNGCNACNYTNTTYTCNAARATHYTNAGYMGNYTN CARGARGARGARYTNGCNAGYGCNAAYATHCCNGAYYTNGTNTCNTGYCCNTTYTGYAGY TTYGCNACNATHATGTCNGAYCCNAAYGAYAARGTNTTYAARTGYYTNAGYCCNGAYTGY YTNAARGARTCNTGYMGNYTNTGYMGNGARGARAAYCAYGTNCCNYTNMGNTGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TCNCARGTNYTNCARTGYTCNYTNGAYMGNGAR YTNAAYYTNTAYAGYGAYGTNAARGARMGNGTNAAYCCNGTNGCNAGYGTNATHYTNYTN GGNYTNGTNAGYCARCCNGTNGAYCAYGARGTNTAYAGYCAYMGNAARCAYATHTCNTCN GAYGCNGAYMGNTCNCCNGAYGTNGAYAAYGAYAGYGAYGARGAYGARGTNCCNGARTAY AAYGAYGAYTCNTCNAAYGAYGAYATGAGYGAYAGYGARCCNACNATGATHGARCCNMGN TCNMGNCCNMGNAARYTNAGYMGNTCNAARATHMGNCCNGCNGCNGCNCARMGNAAYATH AARCARAARTTYMGNGCNYTNYTNAARAARTTYAARATHTCNGARGAYGTNYTNATGGAY TCNGARGCNGAYCAYGAYCARATHGARCARCCNYTNGAYGAYYTNTTYGAYGARYTNGAR GAYTCNGAYAGYGGNCCNGARYTNGAYACNATGAGYATHATGTCNACNCCNAARCCNMGN ATHAARCCNTTYTTYGCNGGNMGNGGNACNTCNYTNGARCCNACNGAY---CCNAARACN TCNTCNCARGAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATHTAYTAYTTYATGTGYGAYTTYCAYGCN GCNTTYATHAGYCCNGAYTAYCAYCAYGARTAYGAYGAYYTNYTNTTYYTNTTYTGYTTY ATGTAYCAYAARATHMGNCARCARAGYCARATHYTNGTNATHMGNMGNMGNGAYATGATG GARAARAARACNGCNCARGAYTAYCCNGAYYTNGCNGARAARTAYGGNATHCCNCARCAY TTYGGNYTNTAYTAYGCNATGGGNYTNGCNYTNGTNATGGARGGNTTYATGAGYGCNTGY TAYCAYGTNTGYCCNAAYTAYTCNAAYTTYCARTTYGAYACNTCNTTYATGTAYATHATH GCNTGYYTNATHATGYTNMGNGTNTAYCARACNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TTYAARAAYATHCCN YTNAAYCCNTAYGARTCNGARATHYTNAARYTNCARGARACNATHCARCAYYTNAARGTN CARCARACNATHGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARTGYGTNACNAAYATHTTYGCNAGYGTNGTNAARACNMGNCARCAYCARGAY CAYYTNYTNGARCAYGGNGCNATHAAYATHYTNTGYGGNTTYYTNGARAAYGCN---CCN TAYAARGTNCARATGCCNTGYYTNAARTGYYTNGGNGCNATGTGYCAYAARAAYCARCCN GTNTGYGCNGCNATHGCNACNAARAAYTTYCARAAYGAYATHATHGTNMGNYTNATGACN TAYGAYAARCCNTGYGARATGCARATGGCNTGYGCNMGNGTNYTNACNTAYYTNCAYMGN GGNCAYGTNYTNGGNCCNGAYGAYCCNGTNATHAARCAYAARACNATGCAYACNYTNGTN MGNATGTGYAARAARGAYMGNACNYTNGARGARAAYGTNGARGGNGCNCAYATHYTNGCN TAYYTNATHGARACNGAYCCNGGNYTNCARGARATGGCNAGYGTNACNGAYCAYYTNGTN CCNGCNYTNCAYGARTAYYTNAAYTAYAARGAYGTNCARAARGTNACNTCNAAYCAYAGY AARAAYATHAAYAARYTNGAYGARATGAARCARGCNGCNTTYYTNGCNTTYGCNTCNYTN TGYGCNGAYCAYGARGAYATHMGNGARAARGTNYTNMGNAGYGARACNATGATHGAYAAY YTNGCNGGNGCNYTNGCNAGYTCNGAYATGAGYYTNTGYTCNGCNGGNYTNMGNTGYYTN YTNAGYYTNTCNMGNTCNGTNCARCAYATHMGNACNAARYTNAAYAARCARGCNYTNTGG GARCCNGTNYTNAARYTNGCNTCNTCNGARATHAGYGAYATHAAR--------------- ------------------------AAYTTYTCNYTNGAYTTYTGYCCNTGGAARGCNCAR ATGGTNGARMGNGGNYTNGTNCARGTNYTNGCNAAYATGTGYGTNGAYGCNGAYCCNTGY ATHAARATGAGYGGNACNTGGGGNYTNGTNAAYTGYATGTAYAAYGCNCCNYTNAARATH MGNGARTCNATGYTNGAYTGYYTNCCNGCNAGYGAYYTNGTNCARYTNTGYTTYGAYCAR GAYATGMGNATHMGNGARAARGCNATHGCNATHYTNMGNAAYATHYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGTCN ACNTTYATHMGNMGNTAYGCNAARTAYYTNAAYGARAARGCNGTNTCNTAYMGNTCNATG GCNTTYGAYTTYTGYAARGTNAARMGNGGNAARGARGAYGGNYTNYTNMGNACNATGAAY TGYGAYAARYTNYTNAARACNYTNCCNGTNYTNCARCARCARYTNGAYGCNYTNYTNGAR TTYGAYTGYACNCCNAAYGARYTNACNAAYGGNGTNATHAAYGCNTGYTTYATGYTNYTN TTYAARGAYYTNATHMGNYTNTTYGCNTGYTAYAAYGAYGGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNYTNCARGARTGGGCNAARTTYACNAAYMGNTAYGTN GARGGNGARAARAARGAYTGGCCNGTNTGGAARACNMGNTTYMGNTGYGCNYTNAAYAAR YTNCARGAYATHCARGARCARAARGARYTNACNMGNYTNGAYGTNTCNGARCCNTAYAAR GTNTAYAARTTYGTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARGAYGAYTCNGGNCCNCCNCCNGAYCCNGTNTAYAAYTTYYTNGCNGAYMGN MGNMGN------------GAYGAYMGNAARGAR------------GTNMGNMGNGAYGAR ACNMGNMGNCAYCCNMGNAAYTTY---GGNGGNACNGAYTTYAAYAARGCNAARGCNCAR GTNAARACNGTNAARGARAARGAYTCNTTYAAYAAYGCN------AARTCNYTNGARATG ACNATGACNGGNAARGARMGNAARAAYTAYCARGAYTGGAARGCNGARMGNGARAARGTN GAYGCNGARMGNATHYTNMGNCARAARACNAAYTCNGGNGARTGGMGNMGNGARTGGGAY TCNCAYAARATHGARYTNGARTAYGAYGAY---------CCNCCNGTNMGNACNGARCCN GCNAARMGNCCN------------------------------------------------ ------------------------------GCNGGN------------------------ ---------------------------------------------------------MGN ATHGGNAGYGGNMGNTTYGAYMGNGGNGAYMGNGARGARMGNCAYCARCCNAARCCNGAY CCNCCNCARGGNGTNGCNGGNTCNMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNMGNGGN MGNGGN---------------------------GGNGCN---GARAARTCNCCNMGNCCN MGNACNTGGTCNGGNGGNGAYGARMGNATGGTNGARTGYCARAARCARATGYTNYTNGTN AARTTYGAYAAYACNGGNGAYGAYGAYTCNGTNGARGTNGARTAYGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MGNGCNCCNMGNTTYGGNAAYGAYAAYAGYAGY GTNAAYMGNCARTCNMGNTCNCARACNACNMGNCCNGAYCCNATHCCNGGNCARCCNTAY GCNGGNGCNCCNGCNCARAARGTNGGNAGYGCNCCNYTNMGNAARATGGGN---AGYCAR CCNCCNACNATHMGNGGNAAYGGNACNYTNGCNAAYAARACN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AAYYTNACNYTNGGNYTNAAYGTNGGNGGN MGNCCNTAYTCNGCNGCNCCNGGNGCNGARACNGCNAARTAYMGNGCNACNGGNYTNGTN TCNCCNGGNAAYCCNYTNTTYGGNAGYTCNTTYTTYCARACNMGNAAYATGGCNTCNMGN AGYGCNAGYATGTCNAARGARGTNACNMGNAGYMGNYTNYTNGARGAYTTYMGNAAYAAY MGNATHCCNAAYYTNAGYYTNAARGARYTNGCNAAYCAYGTNGTNGARTTYTCNCARGAY CARCAYGGNTCNMGNTTYATHCARCARAARYTNGARMGNGCNACNACNCARGARAARGCN ATGGTNTTYGCNGARATHYTNTCNGCNGCNTAYAGYYTNATGACNGAYGTNTTYGGNAAY TAYGTNATHCARAARTTYTTYGARTTYGGNTCNCCNGARCARAARCARACNYTNGCNCAR MGNGTNMGNGGNCAYGTNYTNCCNYTNGCNYTNCARATGTAYGGNTGYMGNGTNATHCAR AARGCNYTNGARTCNATHCCNCCNGAYATGCARGTNGARATHGTNAARGARYTNGAYGGN CARGTNYTNAARTGYGTNAARGAYCARAAYGGNAAYCAYGTNGTNCARAARTGYATHGAR TGYGTNGAYCCNAARTAYYTNCARTTYATHATHGAYGCNTTYAARGGNCARGTNTTYACN YTNTCNACNCAYCCNTAYGGNTGYMGNGTNATHCARMGNATHYTNGARCAYTGYACNCAR GARCARACNGCNCCNATHYTNGARGARYTNCAYGARCAYACNGARMGNYTNGTNCARGAY CARTAYGGNAAYTAYGTNATHCARCAYGTNYTNGARCAYGGNMGNCARGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AARCARYTNATGGARATGACNGGNAARAGYGARGAY GTNGTNGCNGGNGCNYTNCAYGAYGCNAAYAAYGAYGCNGAYACNGCNGTNATGATGYTN YTNGARGGNGGNGAR------GGNGARTGGCARGARCARAGYGCNAARAARAARAARAAR GCNACNGCNAARGAYGGNGTNGARAAYCAYGTNGAYGAYAARCAYGTNAAYGGNMGNATG MGNAGYMGNGGNGARGAYMGNCAYMGNGAYGAYTCNTTYGARMGNAAYGAYMGNCCNCCN MGNMGNGGNMGNMGNAAYGAYGCNTAYCCNCCNMGNYTNGCNMGNGGNMGNGGNMGNGAR MGNGGNGGNTTYTTYGAYMGN------AAYMGNGAYMGNGGNGAYAAYGARGAYTGGGAY AAYGAYMGNATHGARMGNGGNCCNTTYMGN---GGNGAYMGNGARMGNAGYGGNGGNGAR MGNGGNMGNGGNMGNGGNMGNGGNGGNTTYGGNCCNMGNMGNGGNGGNGTN--------- AGYGGNMGN---GGNMGNTTYAAY------TCNGAYMGNGARAAYMGNAAYTTYAAYMGN GTNCCNMGNTTYGARAARYTNCAYAAYTCNCAYTCNGCNGAYGGN------CCNGARATH GAYACNTGGACNAAYGARACNGCNGAR---AAY---GCNGARAARGAYGCNGCNTGGGGN GAYTGGACNGARACNTGGGGNAAYGARGARGAYCARTGGACNGGNTCNYTNGARGARACN AARGTNTTYACNCCNTCNACNATGAARTCNTCNGAYTCNGARGCNATGATHTCNGARCCN CCNAGYTCNYTNGGNCARMGNYTNGAYGTNGAYAGYYTNTTYAARTCNGCNGARTTYACN AARGCNCCNGAYTTYACNAARCCNGCNGARAAYGCNTAYATHACNCARTTYAAYCARGCN GCNACNGARACNATHAARAAYACNATHGGNATHGGNAGYTCNTCNMGNCARCARCARCAR YTNGGNTCNYTNTCNTCNYTNAGYCARGCNTCNGCNAAYGCNYTNGGNYTNTCNTCNYTN GCNGGNAAYTCNGGNCAR------------------------ACNATHAGYYTNCARCAR ACNCCNAGYYTNGCNCARYTNTCNCARTCNYTNGCNCARTCNGTNGCNCARTCNCAR--- ---------------------TCNCAR---------------------------AGYATH TCNTCNCAYYTNCCNGCNCARTCNCARAGYYTNGCNGGNAGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CCNGARGCNATH TCNYTNYTNCCNYTNCCNCARYTNTGGGGNGTNYTNTTYTTYATHATGYTNYTNTCNGTN GGNATGGAYACNCARTTYGGNTGYATHGARGCNACNATGACNACNGTNTGYAGYTTYYTN CCNMGNCCNATGGTNMGNAARTGGMGNGTNYTNATHACNGCNTTYGTNTTYGTNYTNTTY YTNYTNAGYYTNCCNTTYACNACNCARGGNGGNTTYTAYGTNTTYTTYYTNATHGAYTGG TAYGTNGCNTCNYTNGGNGTNTTYYTNTTYGCNATHTGYGARTGYTTYATHGTNGGNTGG ATHTAYGGNGTNGAYMGNTTYGTNMGNGAYATHGARYTNATGGTNGGNAGYAARCCNCCN ATGGTNGTNMGNATHATGTGGTGYTAYGTNACNCCNGCNATHATHGTNGCNYTNATGTTY GCNATHYTNGCNGCNTTYAARCCNGCNACNTAYGGNAGYTAYGTNTAYCCNGCNTGGGCN ACNTTYGTNGGNTGGTTYGTNGCNATHTCNTAYTTYYTNCCNGTNYTNTTYGTNGGNGGN GCNYTNYTNGCNMGNGGNMGNGGNTCNYTNAARCARMGNYTNGTNACNYTNYTNMGNCCN AGYACNGAYTGGGTNCCNTCNMGNCCNGAYYTNMGNGCNCARTAYATGGGNYTNTTYGAY ATHTTYACNGARGARTTYACNACNAARATHMGNYTNATHYTNTAYGCNATHYTNATHTTY TTYAGYTTYTTYATHTTYATHGGNAARGGN------------------------GAYGAR TGYCCNYTNTAYYTNACNATHTCNGGNAGYGGNTTYGAYTTYGGNCCNGARAGYAAYTGY AAYTAYCCNGTNGCNATHGCNATHATHTTYCARYTNYTNTAYACNATHTTYMGNGTNGCN ACNACNYTNYTNYTNYTNYTNGGNAARYTNCCNAARGAYATGGTNYTNTTYCARGAYATG CCNCARTTYATHTAYGTNGTNGTNGAYYTNYTNGCNTTYTTYYTNACNTTYATHGGNGCN TGYATHYTNTCNGCNGGNATGAAYGARACNTGYAGYACNYTNGARTGYGARCCNTCNGGN GCN---------TAYTCNGCNTCNAARGCNGCNCARGCNGGNGCNTGGATHAGYGTNTTY GTNTGGYTNGCNTCNGGNYTNATGGGNTTYATHTTYATGTGGMGN--------------- ------------------------------------------------------------ ---------------------------------------------------GTNTTYTAY ATHAGYCCNAGYCAYGTNAGYYTNAARTCNYTNGAYGARATHTGYCARTAYYTNACNMGN AAYGAYACNTGYAARTGYGGNYTNGARTGYCCNYTNAARYTNGARCARACNTTYAAYTTY GAYCCNAGYATHMGNGGNCARCCNTGGAGY------------------------------ ------------------------------------------------------------ ---------------------------------------------MGNATGGAYGCNAAR YTNMGNAARMGNYTNMGNAARAAYTTYCAYTAY--------------------------- GGNGAYATGGCNTGYYTNGAYACNCCNTCNTTYCCNYTNACNGARYTNGCNGTNGARTAY TTYCARGAYAGYGTN------CCNMGNGARYTNGGNMGNGTNGAYGARTAYATGGCNAGY ACNATHATHMGNMGNAAYMGNGTNGCNCCNTCNTCNGTNGTNACNGGNYTNATHTAYACN MGNMGNYTNMGNTCNAAYAAYCCNAAYTAYYTNAAYTCNATGTCNTCNGCNGAYGTNTTY TTYATHTCNATGATGATGGCNAGYAARTAYYTNTAYGAYGARGGNGTNGARGARGARGTN TAYAAYGAYGARTGGGCNGARTCNATGGAYCARGAYACNGAYCARGTNAAYCARATGGAR ATGGAYTTYYTNAAYGCNATGGAYTGGGGNYTNTAYGTNAGYCARGARGARTTYCARATG TCNYTNAGYGCNATHGARAARMGNYTNGCNYTNMGNGARGGNTTYAARMGNGGNTGGTTY ACNTAYACNGAYYTNGAYYTNYTNACNGAYMGNGARATGATHMGNGCNATGTGGTCNTCN GTNGGNGTNGAYTGGGCNAARYTNATGGCNYTNTGYTCNACNACNTAYGTNGCNGGNYTN TTYAGYYTNYTNGTNTCNTCNGCNYTNGCNYTNCARGTNTCNTCNACNATHACNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GTNTAYAAYCAR YTNGARGARMGNTAYCCNGAYCCNAARGAYATGCARATHAAYYTNACNGGNTTYYTNAAY TCNAARAAYGCNMGNACNTTYATGTCNGARYTNTGGGAYCAYYTNACNAGYGCNCARGAY AAYGTNACNGGNATHCCNAGYAARTTYYTNGARCARAARAARGARGARATHAARCARMGN CARGCNGARMGNGARMGNATHGTNGCNTCNYTNAARAARCAYGARGARCARATHAARGAR CARYTNGCNAARGARMGNAARGARAGYGAYCARTAYGGNCARGGNAGYMGNMGNAGYGCN AGYAARAGYCCNGARAAYAARAAYGARAGYGARAARAARGTNAARGAYGARGGNTTYGTN AARACNGAR------TCNGTNGAYGAYACNACNGTNGARAAYGGNGARGTNAARACNGAR GARAARGAYGARAARGARACNGAYGCNTCNAARGARAARATHAARGAYGARAARTCNTCN CCNGCNAARGCNGAYGGNGAYAARGARAARAGYMGNGAYMGNGAYAARGAYMGNMGN--- ------------AARGAYMGN---CAYMGNTCNMGNACNCCNGARAARAARCAYMGNGGN MGNTCNMGNTCNCCNGARMGN---------------AGYMGNMGNMGNMGNTCNAGYAGY MGNTCNMGNCAY------------GAYMGNMGNMGNGAYGTNTCNCCNAARMGNTCN--- CCNCCNMGNMGNMGNTCNCCNTCNCCNMGNMGNMGNCCNTCNCCNMGNMGNMGNTCNCCN CCNMGNCAYMGNTCN---------CCNCCNMGNMGNMGNTCNMGNAGYCCNMGNAARAGY CCNGARCARAARMGNMGN------CAYMGNTCNAGYAGYGAYGAYAGYTCNGAYAGYTCN CCNGARMGNGGNAARAARCCNGCNGARGAYGAYGCNTCNTCNCCNGARAARATGGGNGTN CARCARMGNMGNAAYTAYMGNAARCAYGAYGAYGARGAYGAYAGYGAYGAYCARGGNTCN TCNTCNGGNTCNTCNGAYGGNTCNTCNGGNCCNCCNTCNCCNMGNAGYGGNMGNAARATG GAYCAR------------GTNMGNMGNMGNACNCCNTCNCCNTTYGTNMGNMGNACNCCN CCNMGNMGNTCNCCNGAYMGNMGNGCNCCNTCNCCNGGNMGN------------------ ------MGNGGNTTYMGNCCNTCNCCNGCNMGNMGNAGYCCNTCNCCNMGNMGNMGNTCN CCNCAYMGNATGTCNCCNCCNMGNMGNMGNMGNGCNAGYCCNCCNTCNTCNCAYTCNCCN TCNCCNGCNMGNMGNMGNTCNTCNGGNTCNCCNCCNMGNMGNCARMGNTCNCCNCCNCCN MGN---------CCNMGNAARGCNTCNMGNTCNCCNTCNCCNGCNCCNAARMGNMGNMGN CCNACN---GAYTCNGCNTCNCCNCCNCCNGCNAARCCNAARAARCARCCN---CCNTCN GCNTCNGARGARGAY---------TCNTCNTCNGAYTCNGARGARGARGARACNCCNCCN ---MGNAARGTNATGACNAARCCNATHAARGARACNCARGCNCCNCCNCCNCCNAAR--- ---------------------------------------------GARAARAARGTNTCN TCNTCNGARTCNGARTCNGARGAYGAYGAYGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ACNTTYYTNGAYCCNAAYCAYTCNCAYTTYATHYTNTTYACNGTNGARATH CCNTTYMGNGCNAARYTNGAR--------------------------------------- ---------------------------MGNMGNAAYACNTAYACNGCNTGGAGYCCNGAY CAYCCNAARMGNCCNGARGARYTNGTNTAYAAYGGNTTYTTYTTYGCNGGNTAYTCNGAY TGYGTNMGNTGYTTYTAYTGYGGNGTNGGNYTNAARTTYTGGMGNGTNACNGAYATHCCN GCNTAYCARCAYGCNMGNTTYMGNCCNCAYTGYGTNTAYAGYMGNATGGTNAAYGGNCAR GAYTAYATHGAYMGNGTNCARGGNGARATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TAYAARAARAAYAAYGAYATGCAYATH AARACNGCNCARGAYGTNTCNGARTAYAAYGTNATHTCNGCNTTYCAYGARATHGCNACN GGNGARAARTAYGTNYTNCCNACNCCNAAR------------CCNGCNGARGARAARAAR GARGCNGAYTCNGCNACNATHACNGARGTNACNGARGARGARGARGARGGNCARGTNGAR GAR---ATHGARGTNGARMGNTCNGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNCCNYTNTAYCARCCNTCNACNGARTTYAAR TGYATHGARAAYGGNAARGTNATHCCNTTYGARTAYGTNAAYGAYGAYTAYTGYGAYTGY GARGAYGGNTCNGAYGARCCNGGNACNGCNGCNTGYCAYAAYGGNYTNTTYTAYTGYGAR AAYAARGGNTTYAARGGNTTYTAYYTNACNTCNTCNMGNGTNAAYGAYGGNGTNTGYGAY TGYTGYGAYGGNTCNGAYGARTGGGGNGGNYTNATHACNTGYGARAAYACNTGYGTNAAR YTNGGNGARTCNGCNMGNGCNGARCARGARAARTTYMGNMGNYTNCARGARCARGGNTAY AARATHAARCARGARTAYATHCARCARGGNAARMGNACNAARGAYGARAARMGNGCNMGN YTNAGYGARYTNGARMGNGARAARGAYATHGCNGTNCARGARAARAAYGAYGCNGARGCN GCNAARGARGARGCNGARGTNCCNGARMGNGARGCNAARGAYAARCAYGARAARGCNTGG GARGARGTNAARGCNCARAARCARAARGARAARGAYGCNGARGCNGCNGTNAARGCNTTY TCNGCNYTNGAYGCNGAYCAYAAYGGNGTNGTNGAYGTNTAYGARATHATHATGCAYTCN GARTTYGAYATHGAYTCNGAYGGNACNGTNAGYGTNGARGARGCNMGNGARTAYYTNGAR GAYGCNGARCARGTNGAYYTNAAYCARTTYACNGARAARATHTGGCCNAAYATHAARGAR ATHTTYAARMGNGGNGAR---GCNGARGARGCNGCNGARGARACNAARCCNGARCCNACN YTNTCNCCNGARGARAARGARGAY---------CCNGGNCARAARCCN---AARGCNCAR GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNGTNCCNCCNCCNGGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CCNGAYAGYGTN--------------------------- YTNGARATHGTNGGNCARCCNMGNTCNTGYCARGTNGARGARGGNGGNCAYGCNYTNTTY AGYTGYGAYGCNMGNGGNGGNGGNCCNYTNCARTAYGARTGGTTY--------------- ---TTYAAYGGNGTNAGYATHCARGGNAARACNGAYMGNACNYTNTCNYTNATHAAYGTN ACNCCNCAYAAY---ACNGGNACNTAYCARTGYYTNGTNAARCARAGYACNGARTCNGTN YTNTCNGAYGTNGCNAGYYTNCARGTNGGNCCNYTNTCNGTNMGN------------AGY GAYTAYTTYGCNACNGAYAARGTNGCNYTNYTNATHGGNAAYACNMGNTAYMGNGCNGAY AARATGYTNACNGCNCCNMGNGGNGAYGTNCARGARYTNGCNAARGTNTTYCAYCAYYTN AAYTTYAARGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TGGAAYTTYGCNTTYTCNGTN ACNATHGCNACNGTNYTNTCNATHTCNTCNTTYYTNACNATHGTNGGNAAYGGNATGGTN YTNACNGTNATHATHMGNCAYMGNGGNATGMGNACNMGNACNAAYYTNYTNYTNGTNAAY YTNGCNYTNGCNGAYYTNYTNGTNGGNYTNYTNGTNGTNCCNTTYGCNATHACNACNATG GTNGARGGNACNTGGGTNTTYAAYGARTTY---TGYATHATHAAYGGNTTYATGAAYTGY TTYTGYYTNGTNACNTCNATHCAYACNYTNATGTAYATHGGNATHCAYAARTAYTTYTCN ATHACNMGNCCNYTNAAYAAYCCNYTNACNYTNACNTAYATHGTNGGNATGATGGTNGCN GCNTGGYTNTGGGGNGCNTTYTGYGCNACNATHACNATHACNGGNYTNAGYMGNGTNCAY TAYAARMGNGGNACNTCNCARTGYGGNCCNGCNTAYCCNAGYGARYTNAARGCNTAYYTN TTYCAYGGNATHATHCARTTYTCNGCNGTNYTNATHCCNYTNTTYATHYTNGTNTTYTGY TAYATHMGNATGTTYYTNACNATHAARGCNCAYTCNAARMGNYTNCAYMGNAAYTCNACN YTNGARGARGCNCARATHYTNYTNCARCARAARAAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CCNGTNTTYCAR GARGGNCARYTNTCNTAYGTNGGNMGNGAYGCNACNGCNATHCCNCARCAYYTNATHCAR AAYTAYTGYAAYATHACNTCNMGNYTNGAYYTNTCNTTYAAYMGNYTNAGYGAYYTNMGN GGNYTNAAYCARTTYMGNTTYYTNAARGARYTNGTNYTNGAYAAYAAYGARYTNGGNGAY GAYATHATHATHCCNAARYTNTCNGARGTNCAYACNYTNACNYTNAAYAARAAYAARATH ACNCAYYTNGAYGGNYTNYTNGARAARYTNTGYAAYAAYYTNCCNAARYTNACNTAYYTN AGYYTNYTNGGNAAYGARGCNTGYCCNAAYCARYTNAGYTCNAGYGAYAARGAYGAYGAR GAYTAYCARMGNTAYMGNTTYTTYACNYTNTAYMGNYTNCCNAAYYTNAARTTYYTNGAY TCNAGYCCNGTNAARYTNAGYGARYTNACNGARGCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNACNCCNACNCAYAAYYTNCARGAYMGNACN GTNTTYAAYTTYCCNGCNCCNGGNACNACNYTNACNGTNCCNCARACNGAYCARACNACN ACNCARCARATHATHACNATHCCNGTNCCNTCNGGNCARGCNMGNGCNGCNATHGARYTN YTNGCNAARATHTTYTCNGAYAAYGARGTNGCNMGNATHCARGCNGARACNATHMGNYTN GCNAARTTYAAYAAYAAYACNGTNGCNCCNGTNYTNTGGMGNYTNYTNATHGARGTNATH TAYTTYTGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATHGCNCCNAAYYTNGGNGCNTAYMGNGCNGGNTCNYTNCCNAAY GTNAAYCARATHGCNGCNAAYCARAGYATHGAYYTNCARGCNACNYTNCARCAYYTNGAY GAYATHAARGCNGGNMGNCCNAGYACNGAYMGNYTNCAYGGNMGNAAYGAYMGNCARMGN CARCAYATHGGNCCNCAYMGNMGNCAYTTYCCNGCNGAYAARACNCCNCCNTCNCAYMGN MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNMGNAGYCCNMGNTTYAGYCCNGAYMGNTCNMGNYTNGTNTAYYTNGAYACNCCN GTNGGNGGNCCNCAYGCNCARTGYAGYMGNYTNGTNYTNYTNGAYTGGGARTCNMGNGAR YTNACNGTNGTNGTNGAYATGGTNGCNTCNGCNCCNGCNAAYGARTTYCCNGGNYTNTTY TCNTGGGCNATHCARGARMGNTGYTGGYTNGGNGAYAAYGTNCAYGTNGTNATGGAYACN GCNTGGMGNAGYTCNCARGARGCNYTNYTNATHAAYACNAARACNMGNGAYTTYAARAAR YTNTGYGTNGARGGNCAYMGNGGNAGYACNCARGTNYTNGAYGTNATHCARAGYTAYGTN GTNGTNGCNTGYTCNGCNYTNGAYGCNAGYCCNCAYATHGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CAR YTNAGYGGNATGTTYGAYYTNGTNTAYCARGTNAAYYTNYTNGAYAGYAARGAYCCNATG AAYYTNGARYTNYTNGGNMGNCCNGAYYTNAAYGTNACNTTYACNAARTTYCAYTGYTGG MGNYTNACNCARTTYAAYAARGGNGTNTTYYTNGAYGCNGAYACNYTNGTNATHCARAAY GTNGAYGARYTNTTYGAYMGNGARGARYTNTCNGCNGCNCCNGAYGCNGGNTGGCCNGAY TGYTTYAAYTCNGGNGTNTTYGTNTTYMGNCCNGCNGARGAYACNTAYAAYAAYYTNYTN GCNTTYGCNYTNACNCARGGNTCNTTYGAYGGNGGNGAYCARGGNYTNYTNAAYYTNTAY TTYAARGAYTGGGCNCAYAARGAYATHAGYAARCAYYTNCCNTTYACNTAYAAYGTNGTN TCNCARGCNTTYTAYAGYTAYYTNCCNGCNTTYAARCARTTYTAYGAYAAYATHAARATH GTNCAYTTYATHGGNGCNATHAARCCNTGGCAYCAYGGNTAYAAYACNGCNACNGGNAAR GTNACNATGYTNCCNGAYTCNAGYCARAAYCARCARTTYYTNGARYTNTGGTGGAARATH TTYATGGARAGYGTNCARGGNTCNYTNGAYCCNAGYYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNMGNGARGCNYTNACNACNAARYTNAGYGCNGAYACN GAYGGNGCNACNGAYGAYATHAAYAARGCNGGNAARMGNATHACNGCNTCNGCNTTYGAR TTYYTNGAYACNTAYYTNTCNGAYGAYGAYGGNACNGAYATHAAYGTNGAYAGYCCNCCN YTNTCNCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATHACNCCNCCNYTNAGYTCNTCNTCNAGYCCN------------------CCNTCNCCN GCNTGGAGYGAYAGYAGYAGYAGYATH------------------------------YTN ACNAARTTYCAYCCNAARGCNGCNAGYCARGTNCCNMGNCAYCARMGNCCNTCNCAYAAR MGNGCNGARATHAARMGNMGNGAYAARATHAARACNMGNYTNGAYGAYYTNAARGAYTGY ATHCCNGCNYTNGARGGNACNGGNAARATGAGYGARGCNACNATHYTNATHAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ACNCAYAGYTTY YTNAGYGCNTCNGCNYTNTGYATHACNTCNGGNGTNATHGTNYTNGTNATHGGNTTYYTN GGN--------------------------------------------------------- ---------------------------------TGYCARAARAAYCCNGGNCAYACNGCN TTYATHCCNGTNMGNGARTTYCARYTNGARAGYYTNCCNGGNCCNCAYMGNCAYGARGAR YTNGTNACNYTNATHYTNAAYTGYGCNAARYTNGTNACNMGNATHGTNGCNGGNACNACN AGYAGYGGNMGNCCNMGNTCNGAYCCNTTYMGNMGNTTYAARGGNGGNGGNATGAARMGN AAYGCNACNGGNTGYGTNTTY---------TCNGCNGGNAAYGARGGNAARMGNGCNTGY ACNAAYGCNAAYTGYCCNTAY---------GGNAAYAGYCARGGNTTYGGNTAYATHMGN GTNTGGACNAAYCARCAYGTNGTNTAYAAYAAYGARGARGCNGARAAYGCNGCNGTNGAR TTY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNTTYGTNYTNGAYMGNATGGAYACNCCNTCNACNCCNGARAARTTYTTYTTYGAYACN ATHAARYTNAAYTAYCAYGGNTGYCCNGGNAARYTNTAYATHAAYTAYATGMGNGCNTTY TGGGARTTYTCNAARATHYTNATGTTYYTNTCNTTYGTNTTYATHGTNGTNATGGCNTTY GGNGAYGCNTAYAARGTNTCNACNACNAAYCARYTNYTNGCNACNGTNATGGGNGGNTTY ATHCCNTTYTTYYTNMGNAGYATGTTYTCNTCNMGNGGNGGNATHTCNAGYATHGAYCCN GAYAGYATHCARTTYYTNACNGARTTYCAYAARGCNATHAAYGARTTYMGNCARTCNTGG GGNGTNTAYGAYATHCARCCNACNGARACNGTNMGNYTNMGNCCNCAYGGNCAYTCNMGN GGNAARTCNCAYTCNCCNTGYTCNGAYAARGAYTCNGCNATHGGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARCARGCNGARGAYAARGARTCNCCNMGNGCNCCNAGYCCN GCNGGNGGNGCNACNGARAARCCNTCNGCNAARYTNTCNCAYCCNGCNGTNGTNYTNAAR GTNAARCCNGTNTCNGGNCARCCNYTNCCNGCNAAYGCNTCNTCNAGYATHGCNTCNGCN GTNCAYAARGTNGAYCARGGNGARGTNATHGGNGTNGGNGCNTTYCAYATHYTNAGYGCN GCNCAYYTNGARTCNMGNGAYGCNATGTTYAARCAYMGNCAYGARGAYATGYTNACNCAY YTNYTNGAYCARACNGARGAYATHACNCCNTCNGCNACNTTYCAYTTYYTNACNGCNAGY AGYATGATHCCNTCNACNYTNGAYTCNTCNGTNCCNGARGGNMGNCCNGTNACNGTNGCN GTNTGGTGGTCNGGNAGYGTNCAYYTNTGYCARTAYTCNYTNYTNAAR---ACNGGNAAR GAYYTNGARTTYAARCCNGAYGTNGTNTGGGCNTTYATGGCNCCNGTNTCNTGYTCNGTN ACNAGYMGNTGYTCNGCNTAYATGGCNATHGGNYTNGTNAGYGGNAGYGTNGTNATHTGG GARMGNMGNYTNGGNYTNCCNAARGCNGTNGTNACNGCNTCNGCNACNAGYGCNGTNCAR TCNATHTAYTTYYTNGAYCCNTCNYTNTTYCCNTCNGAYYTNCCNCAYTAYCCNCCNTAY GCNACNCAYGGNGCNACNTAYYTNYTNGTNAAYTGYTCNGAYGGNTCNCARYTNYTNTAY GAYACNTGYGAYGGNAGYCARCARATHCCNMGNTGYATHGCNGARAARCCNCARAAYGAY GAYGARCARCARATHYTNYTNAAYGTNATHCCNGGNYTNCCNGARYTNATGYTNTAYGTN CARAARAARGGNTCNYTNTTYATHAARGAYGTNACNACNGGNGCNTCNATHTGYCARATH TGYYTNCCNCCNAAYCARCARYTNACNACNCCNTGGGAYCCNGTNATGGCNGTNGGNGGN GGNGGNCARYTNYTNTAYGTNAARGGNGARTGYCARGARGARGGNGARGARGGNGARGTN ACNGTNACNGGNAAYYTNTTYATGTAYCCNYTNMGNTCNTAYCCNACNYTNGAYAGYTAY TGGYTNMGNGARMGNCCNGARGCNGCNYTNGARGTNAAYACNCCNGGNCCNCAYMGNYTN GAYGCNYTNATGAARGARMGNYTNGCNCARCARGCNYTNMGNAARCCNMGNATGCARAAR MGNTGGGGNCARYTNMGNCARGARYTNGAYYTNATHCARMGNTGYYTNGCNGCNCCNGTN GAYGTNYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNCCNACNTAYGCNACNCCNTCNATGTGYCCN CAYAAYGCNGGNYTNGARTCNAGYTCNACNGGNTCNTCNTTYCCNGCNGAYTGYGCNAAR CCNGTNCCNYTNGCNGTNGGNTCNYTNGAYAGYMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GGNGTN YTNGARTCNATHGGNGGNGTNGTNAGYGARGGNAARGARTCNGTNGTNTTYCAYGCNACN GGNGGNAGYATHAARGARGARAARYTNCCNGCNGAYGTNATHYTNAARGTNTTYAARATG TCNYTNATHGARTGGAARACNMGNGARAARTAYATHCAYGGNGAYTAYMGNTTYTCNAAR GARGARTTYAARAARCAYAAYCCNMGNAARATHATHCCNATGTGGGTNGTNAARGARACN GCNAAYYTNAAYMGNATGMGNMGNCAYGAYGTNCCNTGYCCNTCNGTNATHGTNACNAAR AARCAYGTNYTNGCNATGACNTGYATHACNGAYAARMGNGGNGCNCCNCARYTNMGNGAY GCNCARYTNAGYGCNCARGAYTGGCARGAYGCNTAYGARCARACNGTNCAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNAGY YTNYTNGGNACNCARCCNTCNGTNTGYGTNGGNYTNACNMGNGGNGAYATHYTNAARGTN CAYYTNCAYAARCAYCCNGTNATHTTYATGGGNTTYGTNGAYAAYGTNGGNYTNATGGTN ACNGTNGAYGARGCNGGNTTYATHAAYYTNTGGAARTAYAAYGGNMGNCAYGTNACNGGN TTYGGNTGGTTYTTYCCNGARAARAARTAYAARYTNGAYATGACNAARACNATGTTYACN CCNTCNAGYTCNGAYAARGCNAARGTNATHTTYACNGAYATGMGNMGNTCNAAR---ACN AGYCCNACNCARATHGCNGARGARMGNAARMGNGCNCARCARGCNTTYAAYAARYTNGGN YTNAGYGAYCCNTGGCAYATHGARGARAAYTCNCAYACNYTNATHACNTCNATHTAYGCN CCNCCNGGNGARGTNGTNGAYTCNGGNGCNATGTTYAAYATHGTNGTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGAAY CCNTCNMGNTCNYTNGGNTCNGCNGTNGCNTCNGAYAARTGGGAYGAYCAYTGGATHTAY TGGATHGCNCCNATHTGYGGNGGNATHYTNGCNGCNGTNATHTAYAARTTYGTNACNAAY CCNTAYMGNGGNATHGTNGAYATGAAYACNGCNATHAAYAARATG--------------- ------------------------------------------------------------ ------------------------------ATGGCNGAYGCNATHCCNYTNTTYCCNAAR GCNACNTCNYTNATHATHCAYAGYGGNAAYATHGTNAAYTGGAAYMGNYTNAARMGNAAR YTNAAYCARAAYTCNACNGAYGARYTNTGYGARTGYATHTCNTCNTCNYTNMGNTCNTAY YTNGAYAARGCNAAYAARACNGARYTNCARTAYATGAARGARYTNATHTGYACNAAYGAY GARTCNTCNACNGCNYTNACNACNGARGARMGNGGNGAYATHAARATHACNGTNAARATH TTYATGTGYGCNGARCARCCNTCNGAYGTNATHAARGARGCNYTNAAYGGNGTNATGAAR GARYTNGGNGTNCARTTYGTNGARTCNYTNYTNYTNGCNGTNTCNCCNGARGARGGNGAR GAYGARGAR---GAYGCNAGYYTNACNYTNGARGTNATHAARCCNTAYTGGGARGCNATG GARGARYTNGTNGCNTTYGAYAARGTNYTNACNYTNGGNGTNTGYGAYYTNACNAARCCN YTNYTNGARGAYYTNTAYACNTGGGCNAARGTNAARCCNTGYATHAAYCARGTNAAYYTN GARTCNTGYTGYGTNATGCCNACNGAYYTNACNGARTAYGCNMGNCARGTNAAYATHCAR YTNYTNACNCAYAAYGAYCARCARGAYTTYATHCCNMGNGAYAARYTNCARACNACNYTN AGYTCNGTNGCNACNGARMGNGAYAGYGAYGCNTGGTCNCCNYTNTGGGTNGCNMGNTAY TCNGGNATHGTNAARTGYMGNGGNATHATHMGNACNAGYGGNTAYATHTTYTCNGCNTTY MGNGAYAAYAARAARMGNATHYTNACNTGYAGYGARCAYMGNGARMGNYTNTGGTTYCAY CARYTNMGNYTNTTYGARACNATHATHAGYCARTCNMGNCARYTNGTNYTNATHCAYAAR CCNGTNATHMGNCCNYTNYTNACNYTNYTNATHCARGTNGCNCARCCNMGNGCNYTNGCN AAYGGNGARYTNGARTTYAARYTNGTNYTNATHYTNCAYCARATHTGYATHTGYATHTCN CARCARACNGTNATHYTNGARTCNTTYTTYTCNACNGAYGCNGAYCAYGGNCCNACNMGN TTYYTNATHTTYTCNYTNYTNYTNCCNTTYATHCAYMGNGARGGNCCNGTNGGNCARAAR GCNMGNGAYGCNYTNYTNYTNATHATGACNYTNTCNGCNMGNCAYCCNCAYATHGGNCAY TAYATHGCNTCNAAYTCNGAYTTYTGYCCNGTNYTNGCNACNGGNYTNAGYGCNYTNTAY TCNTCNYTNCCNMGNAARATHAGYCCNCCNTCNGAYGAYTGGCAYGCNATHACNAARGAY GAYTGYMGNMGNATHCCNGAYYTNCARATGTTYYTNAAYTCNYTNCARTTYTCNAAYGCN GTNGTNCAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CCNGARCCNATHTAYAAYAAYGARGGNAARMGNYTNAAYACNMGNGARTAYMGNACNMGN AARAARYTNGARGARGARMGNCAYAARYTNGTNCARGARGCNYTNAARYTNAAYTCNGAY TTYAARCCNCCNGCNGAYTAYAARCCNCCNGTNATHMGNGTNAGYGAYAARGTNATGATH CCNCARGARGARCAYCCNGAYATHAAYTTYGTNGGNYTNYTNATHGGNCCNMGNGGNAAY ACNYTNAARACNYTNGARAARGAYACNGGNGCNAARATHATHATHMGNGGNAARGGNTCN GTNAARGAYGGNAARATHGGNMGNAARGAYGGNCARCCNYTNCCNGGNGARGAYGARCCN YTNCAYGCNTAYGTNACNGCNAAYAAYCCNGARAAYGTNAARAARGCNGTNGARMGNATH AARGARATHATHAARCARGGNATHGARGTNCCNGARGGNCARAAYGAYYTNMGNMGNCAR CARYTNMGNGARYTNGCNYTNYTNAAYGGNACNYTNMGNGARAAYGAYGGNYTNGCNAAR YTNMGNCARATHGCNGARTCNCARACNATHGTNACNAAYACNATHATHTGYACNGTNTGY GGNGCNACNGGNCAYATHGCNCARGAYTGYAARCARAARMGNCCNGGNGAYTCNTTYMGN GTNCARCARATGCARACNCCNCARGAYMGNGCNAARATGGAYAGYGARTAYATGTCNYTN ATGGCNGARYTNGGNGARGGNCCNCCNCCNCCNAARAGYGAR---CCN------GCNCCN ---------------ATHMGNCCNACN---GGNCARCCNYTNYTNGGNACNCCNCCNCCN AAYCCNATGGCNYTNAAYAGYCCNTGGCAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GARYTNTTYCCNGGNACNCCNAAYGGNGTN GARMGNCAYGAYYTNACNYTNTTYCCNACNGTNAAYGAYYTNAARAAYCAYATHCAYCAR GCNYTNMGNGAYATGGARAAYGGNTCNYTN---ATHGCNGCNGGNGTNGTNAAYGTNGAR GTNYTNTCNGGNAGYGCNGAYGCNGCNACNGCNGAYCARGARGCNGCNAAYTCNAARCCN GARYTNTCNTCNATGTGGTCNAGYGTNCCNATGCCNGARACNGTNACNGTNACNYTNACN CARAAYCCNGGNGTNGARATGGAYGARAAYGCNAAYGGNTTYCCNTGGGGNYTNGTNGAY CAYGCNGARYTNGCNAARATGYTNGCNGCNGGNYTNGGNAARACNYTNGTNATHGAYAGY MGNTCNTTYYTNGARTAYAAYACNAGYACNATHCAYCARGCNATHAAYGTNTGYTGYTCN AARYTNGTNAARMGNMGNYTNCARCARGAYAARGTNMGNGTNGTNGARYTNYTNGCNCAR ACNTGYCAYYTNGARGCNGAYCCNTCNTGGGAYGTNATHGTNTAYGAYCARTGYACNGAR GAYCCNGGNYTNYTNCARAARYTNGCNTCNACNTTYAAYAGYGTNGCNTTYYTNAARGGN GGNTTYYTNGCNTTYCARGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AAYGTNAARTAYATHGGNTAYTGYMGNTAYCAY TAYAARAARYTNAARAARGAYGTNAAYATHAARGTNATHCCNGCNTTYAARCCNATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TAYTAYGAYTCNTGGTGGATGTGGCARCAYATHTGYYTNACNTGGYTNAGYGCN YTNYTNATGYTNACNTCNCAYTTYYTNCCNCCNCAYTAYYTNGAYYTNYTNCAYMGNAGY GCNAARCAYYTNGGNMGNTGGCARAARGTNGARGGNMGNCAYGCNCAYGTNCCNTAYAAY GCNTGGTCNGARYTNCARGTNTGGCCNCARGGNGCNYTNGTNAARCAYGTNMGNGGNYTN TTY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GTNTAYATGYTNACNTGGATHGARMGNAARATGGCNGCNGCN YTNTTYGGNTCNCCNCCNACNGCNACNATHGAYGARGCNYTNGARAGYTTYATGAARGCN GARGARATHAGYGARGGNTAYTCNAARGARAAYACNYTNTTYATHGCNAARTGYTAYATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CCNCCNAARCCNGTNMGN GCNAAYGGNAGYGTNGARGARYTNGARGGNCARGARATHTAYGAYGAYGCNGTNTCN--- ---ATHAAYATHACNTCNGARCCNTGGTAYTTYGCN------GGNMGNAARGAYGGNGAR CARAARYTNMGNGARATGGGNAARCAYGGNGGNTTYYTNATHMGNGARTCNGGN---GGN GAY---------CAYCCNTAYACNYTNYTNATHTAYATHGAYGGNGGNATHAARAARYTN AARATHMGN---MGNMGNTCNGAYGARAARYTNGCNATHGGNGARGARAARCCNGAYGAR GTNGCNTTYMGNGAYYTNTCNGARYTNGTNACNCAYCAYAARAGYAAYGAYYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGTTYAARAGYGTNGCNATHGCNAARAAYTAYTCNAAYCCN CARGCNCCNGTNCAYTTYGTNACNGGNGCNGTNAGYCCNTGGGARGCNGARTTYAAYTTY ACNGAYCCNAARCCNCAYTGGGTNGCNTAYMGNCARGARAAYGAYACNGAYYTNAGYTTY GGNMGNYTNAARATHATGAAYGCNACNGTNGCNGTNTAYGARCARGTNTCNYTNCARGAY GGNGCNACNATGGAYTCNGTNACNATHGTNCARGARCAYCAYGGNATGTTYTCNACNACN AAYYTNCCNCCNAAYGTNACNAARGARATHGAYCARAAYAARGTNCARGARGGNGGNAAR CCNGGNATHYTNGAYATHCAYGARATHGGNGGNGCNGGNAGYAAYGCNGAYTCNAAYAGY YTNATHGAYGAYGAYAAYMGNACNMGNGARATH--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNAARACNACNACNCAR MGNGCNGTNCARGCNGARACNYTNGTNACNAARYTNAARYTNGARGTNAARGGNYTNCAR AGYCARGTNCARGTNYTNACNGCNGARGTNACNGCNYTNCARTCNGGNGAYTCNGGNATG GCNGAYATHMGNGARMGNACNAARTAYACNGCNGARCARYTNCARACNGCNGCNGTNGTN GCNCARMGNAAYYTNAARGARYTNAAYGARGGNGTNGARAARYTNAARYTNYTNTCNYTN GTNATGTCNTCNTAYGARAARTTYTCNGAYGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARTCNAGYAARAARCARYTNGARTCNAAYCCNGAYYTNTAYMGNYTN GAYTCNTCN------------------------MGN---TCNGGNTCNGGNTCN---CCN GARMGNYTNGARCCNTTYMGNTGYGGNACNCCNTCNTCNGGNGARAAYATGACNTCNGCN MGNMGNMGNCAYGAYTAYGGNGARGCNGTNMGNAARCAYAAYGCNMGNCCNAARACNGCN GCNGARTAYYTNGARAAYYTNGARCARGARMGNMGNAARMGNGCNCAYTCNGCNCARMGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNGTNYTNACNGGNCARACNAGYGAYAAY ATHTCNAGYYTNGTNATGCAYGARGTNMGNGARYTNGARACNTGGATHYTNMGNYTNYTN AGYGCNCCNGTNCCNGTNCCNGGNAARACNMGNGTNGARGTNAAYGTNYTNCCNAARGAR YTNCARGCNCCNYTNATGTTYGCNYTNCCNGAYAAYACNMGNTTYAGYYTNGTNGAYTTY CCNYTNCAYYTNCCNYTNGARYTNYTNGGNGTNGAYACNTGYYTNMGNGTNYTNTCNGCN ATHATHYTNGARCAYAARGTNATHYTNCARTCNMGNGAYTAYAAYGCNYTNTCNATGTCN GTNATGGCNTTYGTNTCNATGYTNTAYCCNYTNGARTAYATGTTYCCNGTNATHCCNYTN YTNCCNACNTGYATGGCNTCNGCNGARCARYTNYTNYTNGCNCCNACNCCNTAYYTNATH GGNGTNCCNGCNAGYTTYTTYGGNTAYAARAARGAYTTYCCNYTNCCNGAYGAYATHAAR ACNCAYYTNAARCARGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CARGARGTNAARGCN AARGARATHGTNGARMGNYTNAARYTNCCNGTNYTNACNTTYGCNTCNGGNCCNACNAAY AGYATGMGNGGNGCNACNYTNYTNTCNGAYYTNAARGARGCNATHGTNGTNGAYATHGGN GGNACNACNTCNGAYGTNGGNGTNYTNAARAAYGGNTTYCCNMGNGARGCNGCNAGYCAY ATHAAYGTNGGNGGNGTNMGNACNAAYTTYMGNATGNNNGAYGTNGTNAGYATHGGNYTN GGNGGNGGNTCNTAYGTNAARGARAGYMGNGAYGCNTCNGGNGARATHTGYAARGTNAGY GTNGGNCCNYTNAGYGCNGGNTTYAAYYTNAARMGNGARGCNTAYATHTTYAGYGAYGGN AGYGAYYTNAARGAYMGNTTYGTNACNGCNTCNGAYGTNGCNGTNGCNGCNAARATHACN TCNTTYGGNGAYGCNAGYAARGTNGCNCARYTNGAYGARAARYTNATHGGNATGGCNGTN GAYGARATHCAYYTNATGGTNGARAARYTNGTNGAYGTNATHAARYTNAGYMGNGARACN YTNCCNGTNATHATHGTNGGNGGNGGNAGYATHYTNATHGAYATHAAYMGNCCNYTNMGN GGNGCNACNAARATHATHGTNCCNGARCAYTTYGGNGTNGCNAAYGCNATHGGNGCNGCN YTNAGYAARGTNTCNGTNAAYATHAAYACNATHGCNAAYYTNYTNGARATGGTNAAYGTN CARGCNATGGARGARGARGTNAARAARGCNGTNGCNGCNGTNGAYGAYCCNGAYGGNAAR GARAARTAYATHGCNGARGARTCNGCNMGNAARCCNTTYTTYTCNCARGCNMGNGAYGAY GCNATGGAYGARYTNTAYAARAARGCNCARACNTCNGCNGTNGARGCNGGNGCNGAYAAR GAYACNYTNGARGTNYTNGARAARGAYGAYGTNGTNYTNTCNTAYYTNCCNGGNAAYGCN ATHCARATHAARATGAARGTNGTNGGNGAYYTNGAYGAY---AGYAARATHMGNGGNACN CARGTNAARGARTGGAAYAGYCCNCAYAAYGCNACNGARYTNYTNAAYGCNGARAGYCAR GTNATHGARAARCARACNGTNTCNTCNACNGGNAARAARYTNGTN---TCNGARGAYAGY AARGAYMGNGAYGCNACNAARTGYCCNCARGARCCNTAYATHGAYCCNTCNACNGGNGAR TGGATHYTNTCNGARTGGGAYATHGARTGYATHATHGTNGGNGCNGGNATHTAYGGNTGY GGNGGNGGNGCNAGYCCNCAYATGGGNAARYTNMGNTCNYTNMGNGCNATHMGNMGNGGN AARMGNYTNMGNGTNATHAAYCCNGAYMGNYTNYTNAARGAYGCNGGNCCNGAR---GAY YTNGTNGTNGTNTCNGCNTTYATHGGNGCNCCNYTNATHATGTAYGARCARGGNGTNTCN TCNYTNGARACNACNMGNGCNYTNCARACNATGMGNGAYGTNTAYGARATHGGNGGNTAY GARGAYGGNGAYYTNMGNAAYAARGARGGNGTNAAYATHGARAGY---GARGCNGGNAAR AARTTYGTNAGYAAYTAYMGNCCNACNTCNAGYGCNAARTTYCCNGGNMGNMGNYTNATH GCNGCNATGTCNGCNGARATHGGNGGNATGAAYGCNATHGARCCNTTYATGATHGCNGGN AAYATGGAYYTNCCNATH------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TTYMGNGAR AARGTNCARCCNGTNYTNCCNACNATHCCNAARAARGARAGYCCNGGNMGNAGYGAYTTY AARACNATHMGNGARYTNTTYGARTTYATHATHGARGARGAYAARAARGARAARGCNAAR AAR--------------------------------------------------------- ---------------------GARCARGTNACNTTYTTYMGNMGNMGNTGYGARGGNGTN AGYACNYTNCAYCARYTNYTNCARGARTCNAARGTNGARATHGCNAARYTNACNCAYCAR MGNAARGTNYTNGARACNGCNGTNACNAAYYTNMGNAAYMGNYTNYTNGCNAAYAARATH TCNTGYAGYGTNGCNATHGARGARACNGARYTNTTYGTNCCNGGNGCNTCNAARCARACN YTNGAYAAYYTNGCNMGNGARAAYGCNMGNYTNMGNAGYYTNATHAARAAYTCNGARAAR GCNACNGARGARAARGTNAAYGAYATHAARGARACNATGAAR------------AARGTN GARACNGARAAYGARGARYTNAARAGYCAYATH---------GARCARCARAARATGGAR ATHGTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GGNYTNAAYTGYGTN CARTGYAAYCARGGNGTNCARAAYACNTGYAARGCNCCN--------------------- ---------------AARGAYATGACNGAYTGYGTNGGNTGYATGAARTCNATHACNMGN GTNMGNYTNMGNGAYTCNGGNTAYATHAAYGGNTGGGARMGNGTNTCNGARGTNGTNTCN MGNTAYTGYATHMGNMGNAAYATGAARAARGARGGNTGYTAYMGNATGCARAGYAAYGGN GGNTGGTCNGARGTNTGYTAYTGYTAYAGYGAYAAYTGYAAY------------------ ------------------ATGCAYGGNAGYATHGGNTTY------MGNAAYGTNACNTTY GTNYTNTTYTTYATHGTNTTYGTNTAYYTNYTNTTYYTNTAYCAYGGNTCNCARAAYAAY YTNTAYGAYGCNGARATGYTNGGNGCNMGNTAYMGNMGNGARGCNGARGCNAARACNGAR GARYTNCARGARGTNATHAARYTNAARGAYGARAARCARGARAARTGYGAYAAYGARMGN GCNGARTTYAAYACNMGNYTNAARTCNATHAAYCARCARTAYAGYATGYTNCARAGYCAR CAYAARGARCARGARGCNGAYTTYATHAARYTNCARCARGAYYTNGARACNCARMGNAAR GARTGYGAYCARYTNGARACNCARCAYGCNCARGARTAYCARCARYTNAARCARCARAAR GARYTNGARATHGCNTCNYTNAARGAYCARYTNGCNGAYGTNCARMGNCARAAYAAYGAR YTNAARATHACNATHGARAAYYTNMGNCARCARATHCARTCN------------------ ------------------------GAYCARCARCARYTNCARCARCARCAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TTYTTYATH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GARATHGTNCCNACNGARGGNMGNGGNYTNGAYTTYTTYGGNYTNTCN CAYCCNGTNGTNCARAAYYTNATHCARAGYTGYCCNGGNGCNMGNAARTGYTCNCAYTAY AARTGGGTNAARTTYGARATHAAYAARGCNGARACNAAYGARAAYGTNGCNGTNGGNACN GAYGAYCCNACNGTNGGNTTYGAYGCNTTYMGNMGNTGYYTNGARYTNGCNAAYGCNMGN MGNCCN------GTNCCNCCNCAYYTNGAYCARTCNACNAAYYTNMGNTCNYTNYTNACN AARGTNAGY---ATGAARYTNGTNGTNGAYAARGTNYTNCCNTCNGGNGCNMGNTTYGGN GTNATHTCNCARACNGGNMGNCARGGNAAYAARAGYYTNCARACNCCNYTNTGYATGYTN TAYACNMGNAARGGNAGYGTNCCNTAYYTNGAYGCNGAYATGYTNTCNMGNATHGAYGCN GTNCCNGAYATHGCNGTNATGCCNTTYGAYMGNTTYACNGAYCAYGTNGAYGCNYTNAAR GARTTYGGNAARGGNYTNACNGARTTYACNGTNATGCARAAYMGNYTNATHTTYAGYACN ATHCAYGAYGTNGGNACNAAYATHCCNACNGGNCAYAAYGARAGYYTNAGYGTNGCNGTN TGGGCNAARGGNGGNAARGTNAARGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GCNYTNGCNTTYTAYGCNATHGAYGAYYTNMGNMGNTGGMGN TTYCCNATGGCNACNGCNGTNATHTGGATHYTNACNAAYYTNTCNTGYATHATHYTNACN CARGGNGCNGTNTTYGTNYTNGCNTCNGCNYTNGTNATHGCNATHGCNACNGTNGGNYTN TGYCARGTNCAYACNMGNATHYTNGAYAARGTNYTNCCNTCNAGYMGNMGNTCN---GTN YTNACNGARGARGCNACNGARCCNGGNACNYTNGARACNGTNCARAAYTTYAARTAYAGY YTNATHGARATGCAYGAYTTYGTNGTNAARAGYAAYGARTAYYTNAGYTAYTTYTAYTCN ATH--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MGNGARMGN CCNYTNAGYCARGAYATHATHCARGARAARYTNAARAARGCNGARGARMGNMGNGTNTCN YTNGARCARGARMGNYTNCARCARYTNGCNMGNGARMGNCARMGNGCNYTNGAYGTNGTN ACNAARGCNCARACNGAYAGYAARATHTTYGCNCARACNACNCARGARAARYTNMGNMGN TCNATGGARATHAARMGNGARAAYMGNGARCARCARATHMGNTCNYTNCARGARMGNYTN AARGARCAYTGGGCNMGNGTNGCNGARACNACNMGNCARAGYGARGARATG--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CARTGGGTNTCNACNATHGTNGGNTTYNNNNNNNNNTAYNNNNNN NNNAGYTGGAGYGCNGARCARGTNGTNGGNCCNCCNAAYGTNTAYCCNAGYTAYGGNGAY ATHACNGGNACNTGGGCNCCNMGNGTNATHGAYGCNAAYCARTAYYTNGARYTNGGNTTY GAYAGYCCNGTNGTNGTNTCNTCNGTNAAYATHTAYGARACNTAYCAYGCNGGNGGNGTN ATHAGYGTNYTNGGNMGNAAYGGNGAYGAYGARTGGCARGTNYTNTGGGARACNCCNAAY CCNGARGTNATHACNCARAGYMGNATHTTYTCNCCNCCNYTNACNCCNTTYTTYYTNCCN ATHAAYCARYTNMGNYTNAAYATHGAYGCNAGYGCNGCNGGNTCNTGGACNGARATHGAY GCNGTNCARATHGAYGGN------TAYGCNGGNGAYTTYGCNGCNGAYGAYGTNACN--- ---GGNGAYYTNGCNGAYYTNGTNAAYAAYAARYTNYTNTCNGAYGTNAARYTNAAYGTN AARGGNGARAAYATHTTYGCNCAYAARGCNATHYTNGCNGCNMGNTCNCCNGTNYTNMGN AARAARTTYAGYAGYAARAARYTNAARAARYTNGTNCCNAAR------CARATGACNCCN MGNGCNATGATHAAYGCNYTNMGNTTYATHTAYACNGGNMGNATGACNGAYATGAGYCAR GTNGTNGAYTTYGTNCCNGTNYTNAARYTNGCNGARAAYYTNMGNATGCCNGARATGAAR AAYGCNGCNYTNATGAARATHGTNTTYAAYYTNAAYGAYTCNAAYGCNGAYGCNATHTGY ATG--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------ACNACNTCNGTN AGYAGYAGYGAR---GGNGARACNATHATHAGYTAYGTNTCNMGNYTNTGYAGYMGNGAY CCNCAYCARYTNTTYYTNMGNYTNGARTCNCARGTNMGNGARTTYGTNATHGARATGAAR GTNYTNYTNYTNAARCARYTN---AAYGAYGGNTAYAARACNAGYCARCARGCNTGGGCN TTYGCNTCNYTNYTNYTNAARCARTAYMGNYTNYTNTGYAGYGTNTCNAAYYTNYTNTCN CARTAYYTNYTNCCNYTNMGNGARCAYYTNGARMGNTTYAARATHACNTGGGARYTNCAY AAYAARCAYYTNTTYCAYTCNATHGTNTAYCARGAYCCNGCNATHAARAAYAGYTTYTCN ACNGTNCARGAYYTNYTNMGNCARGGNYTNGAYGCNAARGARACNTGYAARGAYGARAGY TAYCCNGCNYTNYTNAARGARTTYATGGAYYTNGARAAYAARATGTCNGTNGTNGGNGCN GTNTGGMGNGAYTGYCARYTNCARYTNGARACNTAYACNGARGARCARACNGCNYTNAAR ATHAARCAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYGCNTAYAAYTGYGGNMGN MGN---YTNGGNTGGCAYMGNAGYMGNCCNYTNAAYTTYGAYGTNACNGCN---ACNGAY AARAARGTNMGNTCNGCNGARMGNCARAGYYTNGTNGAYYTNCCNCCNAAYATHMGNCAY ATGTTYGGNAGYCAYGTNTGYGAYTCNYTNYTNTCNGAYAARACNYTNGTNGAYCARGCN GTNGARMGNCARAARACNYTNAGYGCNCCNCCNMGNCCNTCNAARAARGARGARGTNCAR GCNYTNCCNGTNGAYATGGARGGNAAYTAYGARACNYTNGGNCAYTCNACNMGNTAYAAY GTNTTYCCNGGNYTNTCNACNGAYGAYAARATHAGYAARACNCARAAYGAYTTYAAYGAY ATHGTNCAYYTNMGNMGNGTNCCNAAYCCNGAYGARTAYMGNTAYMGNMGNGAYGGNYTN AGYACN---TGGGCNGARCAYAAYGTNYTNMGNGARMGNATGAARAARGCNTGG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GGN TTYTCNGCNTTYGTNGGNATHATHATHTTYATGATHATGACNGCNGAYATGGTNTCNGAR GGNGCNCAYTAYTCNTGGGGNTTYGGNATGGCNTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNTCNAARCAYGTNYTNAAYAGYATHGAYCCNGGNTAYCCNGTNGTNATH YTNYTNGCNTTYCARGAYMGNCAYAARAAYACNGCNGARTGYGTNGCNAGYAARATHGCN GCNAGYTAYGARGARGCNTTYTCNYTNGARCCNGCNMGNAAYMGNTTYGAYTTYAARGAY GTNGCNGCNYTNCCNGGNGCNGARCARAARYTNCARYTNGAYYTNAARYTNGGNCARGCN TTY---AGYMGNGGNGCNAARTCNTTYGTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GCNGARYTNGARGAYTTYTAYMGNMGNCAYTAYAARGAYAGYCARYTNCARTTY CCNCARGAYTAYCCNTCNGCNTGYYTNYTNGGNTGYGTNCARGTNGAYGAYTGYYTNGAY CARGARCARTAYMGNGAYCARTTYCCNGGNGGNGARTCNGCNTCNCCNTAYGTNTTYATH TGYTCNAAYCCNMGNCARYTNYTNGTNAARTTYCCNATHAARGGNAARCAYAARATH--- ---------------------------------------------TGGYTNMGNMGNTGY AARCCNTGGYTNGAYGAYGAYGGNATHYTNTAYAGYTAYACNAAYACNGCNCCNGCNCCN AGYAARGAYTTYTTYCARGTNYTNGTNACNACNGAYAARGTNTAYTTYMGNTGGTGGMGN ATHATHCCNCCNGGNMGNGTNGAYGCNGGNCARGCNCCNCARGARTAYGTNGTNAGYTAY GARGAYTTYTTYGARGAYGCNCCNATHCARAGYAARATHGARTCNATGGCNGGNGTNMGN GARYTNGARTAYYTNGARAARYTNYTNAARGGNCAYATHGAYTAYYTNACNMGNYTNCCN MGNAARGTNYTNATGMGNATHYTNTTYAAYGCNGAYYTNGTNACNATHACNMGNYTNGCN CARACNTGYAARYTNTTYMGNGARYTNTGYTAYAGYGARGCNYTNTGGGCNAARATHTAY AARGARCAYACNGTNCARCCNATHACNAAYGARYTNYTNATGYTNGTNGAYCARAARGGN TGGMGNGARGTNTTYTTYATGAAYAARYTNCARYTNCARATGCARATHAARMGN------ ---------------------------------------------CCNGCNGTNCAYYTN CAYCCNCCNYTNGCNTAYYTNATHGTNTTYGCNYTNYTNTGGGTNTCNGCNTTYGARCAR MGNGGNAGYGTNGARGTNTGYTGGGAYAARTAYGARATGGCNMGNGAYGAYGTNGARACN MGNTTYCARGCNTCNACNGAYAGYGARTCNCARTGYGCNGCNYTNMGNACNTAYTGGGGN TGYATHACNGARTCNTCNGGNTGYCARGGNGAYATHMGNTAYTAYAGYGTNMGNAAYGGN GTNAARAAYCARYTNAARAAYTAYAAYTGYACNYTNACNGGNCCNACNATHGARCCNTCN GGNTCNAARMGNCCNCCNATGGTNCCNGCNGTNTGYYTNTAYCAYGGNMGNMGNGTNTAY MGNCAYTGYGGNYTNTTYGGNGAYCCNCAYYTNMGNACNTTYTAYGAYCARTTYCARACN TGYAARGTNAARGGNGCNTGGCCNYTNGTNAAYAAYGARTAYYTNACNGTNCARGTNACN AAYGAYCCNGTNATGGGNAAYACNGARGCNACNGCNACNAGYAARYTNACNGTNATHGTN AARGGNAAYCCNGARTGYTCNTCNAARGAYTTYCARATGTAYCARGCNCARACNAAYAAY YTNCCNGARTCNTTYGAYGAYGGNCAYACNTCNTAYGGNCCNTAYAARAGYGTNGARYTN ATGGTNYTNGARCCNGGNAARCAYGTNGARATHCAYATHMGNTAYATHGARACNGTNATH AGYGTNMGNCARATHGGNMGNTAYTTYGCNTTYGCNATGAARATGCCNGARGAYATHGTN AAYCARACNTCNGGNAAYGAYYTNGARYTNTGYGCNMGNGGNTGYCCNTCNAGYGARMGN ATHGAYTAYCARGAYTAYYTNGCNAARAARAARGCNMGNTCNACNGCNGARTCNYTNTGY MGNGCNGCNAAYYTNGTNGAYTTYTAYTTYGAYTCNTGYGTNTTYGAYYTNATGGCNACN GGNGAYMGNAAYTTYACNYTNTCNGCNTTYAGYTCNTTYCARGAYYTNATGAARYTNCAY CCNTTYGCNAARMGNACNYTNGCNAAYMGNACNTCNYTNGARACNTAYGAYGARYTNTAY GGNAGYAGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNYTNMGNAAYGTNCCNGTN YTNAGYGTNYTNYTNGCNGARGTNCCNGAYAGYGCNAGYMGNAGYGTNTTYGCNGCNTGY CARACNCARATHTGGGCNGTNGARGGNYTNTCNCARATGGCNGTNGCNTCNTAYACNGAR GAYMGNTAYGGNGTNATHCARCCNTCNYTNCCNGCNGTNTTYACNAGYYTNYTNGAYYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CAYMGNATHATHGARAARMGNMGNMGNGAYMGNATGAAYAAYTGY YTNGCNGAYYTNAGYMGNYTNATHCCNAGYAGYTAYYTNAARCARGGNCARGGNMGNATH GARAARACNGARATHATHGARATGGCNATHAARCAYATHAAYATHYTNCARAAYAARGCN GAYGARYTNAGYAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARGARGGNYTNGCNGGNAGYCCNCCNACNCARGAYGARTTYGTNAGYGAY GCNTTYCAYGCNAGYGGNATHAGYGARGAYGAYATHMGNAARGARATGGARCARCARYTN MGNGTNACNGARGGNGGNGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------CCNGCNGARATHAAYGAY GCNTGYTAYAARGTNGTNGTNTGGACNGGNAAYGTNCCNGGNGCNACNTCNGAYGCNAGY ATHTAYATHACNATHAARGGNGAYGCNAAYATHYTNCAYAARACNMGNYTNTGYMGNAGY AARGGNAGYYTNAARTTYTGYTTYATHCARGGNTCNAARGARACNTTYTAYGTNAARTCN CCNCAYYTNGGNAAYYTNGARATHYTNACNGTNGARCAYGAYGGNYTNGARAARMGNCAY AGYTGGTAYYTNGAYAARATHGARGTNATHTGYATGMGNACNCAYMGNCAYTGGGTNTTY CAYTGYAARAAYTGGYTNTCNYTNCAYCAYGGNGAYTTYATGYTNAGYMGNGAYYTNYTN GCNAAYTAYAARGARMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATHGGNGGNATGACNTAYGTNCARACNCARCCNGGNACNYTNGARYTNYTNCCN AAYMGNAARAARMGNATHATHGCNAGYMGNYTNAARAAYMGNAGYYTNGCNATHGCNGCN GCNAARTTYAARAARGAYAAYMGNGGNTCNGARGTNAARMGNAARCCNTGYAARTTYTTY ATHAARYTNGGNACNTGYAGYAARGGNTCNAARTGYCCNTTYGTNCAYGAYCCNGARAAR GTNGCNATHTGYMGNMGNTTYYTNCARGGNAARTGYCARGAYATHTCNTGYCCNTTYTCN CAYCARGTNTCNGARCAYAARATGCCNGTNTGYYTNTTYTTYYTNMGNGGNGCNTGYTCN MGNGAYGCNTGYCCNTAYYTNCAYACNAAYGTNAGYCCNAAYGCNCCNGTNTGYYTNGAY TTYAARGCNGGNTAYTGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MGNAAYGTNACNGAYCARMGNGCNGTNGARTTYAAYATHTAYYTNACNAAYCCN MGNATHMGNGTNATHMGNAARACNYTNGARGAYGTNTCNACNGAYGGNTAYYTNGAYGGN AAYMGNAAYYTNTAYATHGGNGAYGAYGARGTNGCNGTNGCNTAYYTNMGNGAYGGNTAY ACNTCNGARAAYTAYAARTCNCARAARGAYTGGGAYGCNMGNYTNATGATGGARATGAGY CARGCNATHAARTGYCCNAGYATHCAYTAYCARYTNGCNGGNACNAARAARATHCARCAR GARYTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ACN ATHTGYATHGCNTTYTTYATGGCNATHCCNGTNTCNATGATHGTNATGGGNGCNATHCAY AARGAYGAYTGYCCNGCNGARMGNATGATHCCNATHTAYYTNATHGTNGCNGGNAGYTTY GGNGTNGCNAARAAYATHTAYAGYYTNATHCARMGNTGYMGNAARACNGARGARGARMGN CARGARGAYCARAARAARGTNAAYCCNATHGARAGYATHGTNGAYTGYTTYATGYTNGCN TGGTTYATHGCNGGNAAYGTNTTYATHTAYMGNACN---AARGAYGAYTTYCARTCNACN GAYTCNACNGCNGAYGAYTAYTGYAAYTAYGAYYTNTAYTGGTAYGCNTTYTGGATHACN ACNGCNGTNTAYATHYTNGCNGCNGTNGGNTGYTGYTCNYTNTGYYTNTGYGGNTGYYTN GCNTTYGTNTGYGGNAARAARTCNCAYGTNATHTGYGGNGAYGTNACNMGNTCNGARAAR GTNYTNGGNGCNTGYATHMGNGGNYTNTGGATHYTNTCNGTNGAYTTYGTNYTNGARTCN CAYCARGTNTCNATGTGGYTNCARGARCARGAYTAYGTNTTYAGYGTNMGNGAYTCNCAR CCNGTNGARYTNGTNTCNGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------AARAAYTGYGGN MGNMGNTTYCAYATHCARGTNGCNAAYAARGAYTTYNNNCAYGAYYTNATHAARATHATH GGNCCNAARAAYGAYCCNCCNCARGCNGTNCARGARAARGTNYTNAGYATGATHCARACN TGGGCNGAYGCNTTYMGNGGNAAYCCNGARYTNAARGARACNGARAARGTNTAYCARGAR YTNAARCARAARGGNATHGARTTYCCNATGACNGAYYTNGAYAAYYTNGCNCCNATHCAY ACNCCNGCNMGNAGYGTNCCN------GARACNGCNCCNMGN------GARMGN------ ---------------------------AGYATGGTNCCNGGNACNCARCCNCCN------ ------------------------------GAYGGNGGNAGYGCNYTNACNCCNGAYCAR MGNTCNAARYTNMGNMGNGARYTNGARGTNGTNCAYGGNAAYATHMGNGTNATGAGYGAR ATGYTNACNGARYTNTCNCCNTCNACNATHGAYTCNTCNGAYYTNGARYTNYTNCARGAR YTNAAYMGNACNTGYMGNCARATGCARTCNMGNATHGTNGARYTNYTNAAYGARATGGCN AAYGARGAYGTNACNGARGAYYTNYTNMGNATHAAYGAYGAYYTNAAYAAYGTNTTYYTN MGNTAYGARMGNTTYGARMGNTAYMGNACNGGNCARACNGGNCARGCNGARACNCCNGTN GARCCNACNCCNGCNCARGAYCAYYTNCCNCCNTCNTAYGAYCARYTNCCNGCNGCNAAY AAYCCNAARGTNGGNAAYYTNATHGAYTTYGAYGAYGAYACNACNTCNAAY--------- GTNGGNTCNCARYTNGCNGGNYTNAAYATHTCNACNACNGCNCCNGCNCCNGCNGCNCCN GCNCCNCCNCARAGYCARAAYGAYGAYTTYGAYATGTTYGCNCARTCNMGNCARTCNTTY GAYCARAAYMGNCARACNYTNGGNGGNACNTCNTAYGGNAAYCARCARGARGAYACNTTY AARGGNGGNYTNGGNCARGCNGTNAAYGCNAARACNTCNGAYGARGCNACNAARYTNCAR CARGAYGARAARGAYTAYGAYGARATGGARCARTGGYTNGCNAARAAYGCNCCNACNGAY GGNTCNGGNAARCCNCARGARTCNATHACNAGYTCNGARTTYGAYMGNTTYYTNAGYGAY MGNGCNAGYGCNGCNGARGCNYTNCCNAGYATHTCNGCNCARACNGGNMGNGCNTCNMGN CARYTN---MGNAARGAYGARGAYGAYAAYCCNYTNTTYGCNYTN--------------- ------------------------------------------------------------ ---------------------------------GARGGNGTNGARGGNGCNAARCCNGCN AARAARAARTCNYTNAAYCCNTTYYTNTCNGAYACNGARGARGARMGNAGYATHYTNTAY YTNCARGAYGTNMGNATHTCNCARTGGCCNATHATHTAYAGYTCNGARTAYAAYATHAGY TTYTGYGGNYTNGARAARYTNCAYCCNTTYGAYTCNGGNAARTGGGGNMGNATHTTYCAR TTYYTNTGYGAYGCNGGNATGYTNMGNGARGAYACNATHATHGCNCCNTCNGARGCNACN GARGARGAYYTNYTNATHGTNCAYACNAARMGNTAYYTNAGYAGYYTNAARTGGAGYATG ACNGTNGCNGGNATHACNGARGTNCCNCCNGTNGCNYTNYTNCCNAAYTTYATHGTNCAR MGNAARGTNYTNMGNCCNTTYMGNTAYCARACNGGNGGNACNATHATGGCNGGNAARYTN GCNATGGARMGNGGNTGGGCNATH------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARCCNCCNTCNCCNAARMGNCCNMGNYTNGAY TGYGARGAYTGYACNMGNGARGARYTNATHGAR---------AARYTNAARGAYYTNGAR GARGARATHCAYTAYCARAAYAARYTNMGNAARMGNCCNGAYGCN------GAYGAYGAR GAYTGYAARGAYGARGAY------AARTCNAARCARTCNTCNGTNGARAAYGCNMGNMGN GARAAYACNYTNGTNYTNMGNYTNACNAAYAARGARCARGARYTNCARGAYTGYATGAAY CARATHCARGARYTNAARCAR---------------------------------AARCAR AAY------------------------------------GARYTN--------------- ---------------------------------------------------AGY------ ------------------------------------------------GCNTGGAARTTY ACNCCNGAYAGYCARACNGGNMGNMGNYTNATGGCNAARTGYMGNATGYTNYTNCARGAR AAYGARGAYYTNGGNAARATGATHGCNTCNGGNMGNACNGCNMGNYTNGARGGNGARATH GCNYTNCAYAARGCNYTNGTNGCNGARATGAARAARAAYCARAARGARYTNGAYGARTTY GTNGGNGARYTNGARGARGAYGTNGAYGGNATGCARGGNATGATHYTNATGYTNCARCAR CARYTNAARGARACNAARGARCARGTNGTNMGNYTNCARCARGARAAYGARCARYTNMGN ACNYTNAGYACNCCNTCNGARGCNGAYCCNGTNGGNTCNACNGCNAAYGAYTCNMGNGCN GARATGGCNTCNTCNGARGAYTAYMGNAAYTTYAARAAYGCNAAYGAYTCNTGYAGYGTN GTNMGNGARGGNATGACNGARMGNGGNGARGAYGARATHMGNAAYAARGARYTNGAYMGN GGNGAYTGYCCN---ACNGTNGARGTNACNAARATGAARAAYGTNGARMGNGGNGAYGAY ACNCCNMGNGCNATGGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TCN AAYGAYATGGAYGAYGARAARAAYAAYGAYGARGCNTCNGARGGNGGNCARMGNGCNTAY ACNCCNGAYACNAGYGARYTNGARGARTTYGTNYTNMGNCCNGCNCCNCARGGNGTNACN ATGAARTGYMGNATHACNMGNGAYAARMGNGGNGTNGAYMGNAAYATHTAYCCNACNTAY TAYYTNCAYYTNGARCARGAYAAYGGNMGNAARACNTTYYTNYTNGCNGGNMGNAARMGN AARAARAGYAARACNTCNAAYTAYYTNATHTCNACNGAYCCNACNGAYYTNTCNMGNAAR GGNGAYTCNTAYTGYGGNAARYTNMGNTCNAAYYTNYTNGGNACNCARTTYACNYTNTAY GAYCAYGGNGAYAAYCCNAARAAR---GGNGTNGAYGCNGCNMGNCARGARYTNGTNGCN GTNGCNTAYGARACNAAYGTNYTNGGNTTYAARGGNCCNMGNAARATGACNATHATHATH CCNGGNATGACNTCNGARCAYATGMGNGTNAAYATHAARCCNMGNGAYTCNCAYGAYGGN YTNATHGARMGNTGGAARMGNAARAAYATGGARAAYYTNYTNGARYTNCAYAAYAARACN CCNGTNTGGAAYGAYGARACNCARTCNTAYGTNYTNAAYTTYCAYGGNMGNGTNACNCAR GCNTCNGTNAARAAYTTYCARATHGTNCAYGAYAAYGAYGTNGAYTAYATHGTNATGCAR TTYGGNMGNGTNGCNGARGAYGTNTTYACNATGGAYTAYAAYTAYCCNATGTGYGCNYTN CARGCNTTYGGNATHGCNYTNAGYAGYTTYGAYGGNAARYTNGCNTGYGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AGYTTYCCNTGGMGNYTNYTN YTNGTNTTYYTNGCNTCNGTNYTNGCNYTNGTNATHACNYTNGAYATHATHTTYAGYCCN AGYGTNMGNACNTGYMGNACNGTNAARYTNYTNGARAGYTGYGGNYTNYTNGCNYTNATG GARCARGCNTGGMGNAARATHTGYACNTCNAGYGCNGTNGCNGCNMGNTGGGTNMGNACN AARTGGCCNGGNTAYTAYAARTAYYTNAGYGARACNGTNGCNCCNGCNGTNGTNTCNGTN TGG--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNMGNGTNAARTGYCARGGNMGNAARYTNGTN GARAARCCNTCNATHGTNTAYGGNGGNATHAGYGAYAGYATGGTNCAYGCNATGAARACN GARGARTTYYTNAGYGGNAARGARYTNAGYGAYAGYGCNATHCARGARGCNYTNMGNACN YTNAARACNGARYTNAGYCCNGCNAGYGAYACNGTNYTNTCNACNGCNAARTAYMGNCAR GAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------GARATHTCNCARMGNAARGTNYTNGAYYTN AARMGNTGGTAYTGYATHAGYMGNCCNCARTAYAARACNTCNTGYGGNATHTCNTCNGTN GTNTCNTGYTGGAAYTAYYTNTTYAGYACNYTNGGNCAYGGNAGYYTNAGYCCNYTNAGY CARGARGARGCNYTNAAYATHYTNGAYTTYAARCCNCCNTTYGARGAYATHAARTTYGGN CCNTTYACNGGNAAYATHACNYTNATGMGNTGGTTYMGNACNYTNAAYTCNCAYTTYAAR GTNAARGGNMGNTGYTTYTAYATGTAYAARCCNGTNGGNMGNAAYMGNACNGTNGGNGTN ACNTCNGARYTNGCNYTNGARACNYTNCARCARGGNYTNGCNGAYTCNCAYACNACNTTY ATHTAYCAYTGYAAYAAYCAYTAYTTYTGYCCNATHGGNTAYGARGARACNCCNAARTCN TGYGTNGAYGCNTAYMGNGGNCARATGTCNGCNGARGARACNGAY---ACNTGGGTNYTN ATHGGNGAYCCNAGYMGNAARCARCCNGCNATHYTNTGYAARAGYTGGGARGAYATHGAY YTNGAYYTNAAYTGYAARAGYCCNGARTTYYTNGAYATHMGNMGNGGNTGGAARGGNGTN CARACNMGNTCNTCNTCNAARMGNACNGGNGGNAAYYTNCAYTGYYTNATHGCNTTYCAR MGNTGYCAYGGNGCNGCNTCNTCNCCNTCNYTNMGNMGNACNCARATHCCNMGNTCNAAY YTNCCNGTNMGNAARGGNACNCCNTCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TCNGAYAARACNAARAAR---AARGARAARGCNGARGARAAR GARGARATGGARGARGTNACNYTNAAYAAR------TAYAARTTYAARGGNTTYMGNACN GARYTNMGNAAYGTNATGTTYATHMGNTCNGAYATHCCNGAYCCNAGYGARYTNACNATH AARGTNATGGARGAYATHATHTCNACNCAYAAYMGNAARACNGGNTGYATHTTYCAYATG ATGCCNGTNCARGGNGTNTGYGAYTAYGAYTAYTTYCARATGGARATHATGATHMGNMGN GTNYTNGCNCCNGTNTTYGAYCCNGCNYTN---GAYCCNAARAGY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AARMGNMGNAARAAYMGNAAR AARAARAARMGNMGNMGNMGNAARCARAARGGNAAYAARAAYATHTGYAARMGNCAYCCN YTNTAYGTNGAYTTYAAYGAYGTNGGNTGGGAYGAYTGGATH------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATHYTNTCNGGNAARTTYMGNTAYCARGARTAYAGYMGNGARGTNACNTCNMGN TCNGGNCAYACNGCNAAYATHGTNGGNAAYATHYTNTAYATHATHGGNGGNMGNAGYGAY AAYYTNYTNGARMGNGTNCCNGGNTTYCCNGGNGGNACNGCNCCNCAYTGYGCNYTNGTN AGYAAYATH--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARGAYGAR GTNGARGAYAAYGCNGGNTAYGARGAYTCNGAYYTNGGNGCNGTNGARGARCAYAARAGY ATHATHYTNCAYYTNYTNTCNCARYTNAARYTNGGNATGGAYYTNACNAARGTNGTNYTN CCNACNTTYATHYTNGARMGNMGNTCNYTNYTNGARATGTTYGCNGAYTGYATGGCNCAY CCNGAYGCNTTYYTNAARATHCCNTCNATHCCNGAYCCNGARGGNMGNATGATGGCNGTN YTNGARTGGTAYYTNACNTCNTTYCAYAAYGGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARAARGCNGTN YTNCCNAARGAYAARCARGARYTNGAYTGGTGGATHMGNTTYMGNAARCCNTCNGARATH ATHAAYGARAAYGCNTCNTTYTTYTAYGTNGARATHGCNTTYTAYATHYTNGTNTTYYTN ACNTTYATHCAYGCNATGMGNAGYGGNGGNMGNTTYMGNTGGYTNTGGTTYGCNACNATH YTNCAYGGNYTNACNGTNGARTGYGTNAGYTAYYTNATHCCNGAYATHGAYAAYTTYTGG CAYGCNCARTCNTCNYTNATGYTNYTNGGNCARMGNYTNCCNYTNCAYATHATHYTNYTN TAYCCNGTNTTYATHTAYACNGCNAGYGTNGCNGTNGCNCAYATGAAYYTNMGNTGGTGG GCNGARCCNTTYGCNGTNGGNYTNACNGTNGTNYTNATHGAYATHCCNTTYGAYATHATG GGNGTNAARYTNYTNTGGTGGACNTGGCAYGAYGAYGAYCCNAAYATHTTYGAYMGNCAY TAYTGGGTNCCNTGGACNTCNTAYTAYTTYCAYGCNGCNTTYGCNTCNTCNTTYACNYTN GTNTTYCAYGGNATHMGNGCN---ATHTGYMGNCAYGCNCCNAARTAYTAYTCNATGGGN TTYTTYTGYGARYTNCCNYTNGCNGTNYTNACNGGNYTNGTNGCNATGCCNYTNGGNGTN YTNCAYTTYGTNCCNYTNTAYCAYCCNYTNCAYGAYACNTTYGGNATHCAYTCNGARGTN ATHGTNYTNYTNTTYYTNACNYTNTAYGCNYTNATHGTNTGGAGYGCNGAYMGNTAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNTAYGGNTTYACNGTNYTNTCNGGNYTNACNACNTAYGGNYTNGCNTGGYTNYTN YTNTCNATGAAYGGNGAYTCNAARGAYTTYAGYGCNGAYGAYGCNCCNAAYTTYMGNAAY YTNGCNTTYATHGTNGTNGGNATHGGNATGYTNTTYAGYTTYATHTTYCAYTGYTCNATH GARMGNTCNGTNYTNCARMGNAGYAARTAYACNTGGAARGAYTGGYTNAARGARCAYCAR TTYTAYCARYTNGGNYTNGTNTAYATGTGYACNMGNYTNTTYGTNAAYATHAGYCARGTN TAYYTNGCNATGTAYYTNACNGARACNYTNCAYATGAGYAARACNTCNGTNGCNAAYGTN CCNYTNGCNGTNTAYTGYAGYAGYTTYYTNTCNTCNTTYATGACNMGNGCNATGAAYMGN TAYYTNGGNMGNAARACNACNTTYGTNTTYGGNACNGGNYTNGCNATGGGNGTNTGYGTN TGGACNTGGTTYATHCCNTCNTGYTCNTAYCARGTNTAYGGNATGGCNGCNGGNGTNGGN ATGGCNGGNTCNGTNYTNYTNATHACNTCNYTNTCNATGACNGCNGAYYTNATHGGNTCN AAYACNGARAGYGGNGCNTTYGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AGYMGNTCNMGNTCNMGNTCNMGNTCNMGNTCNMGNCAYMGNMGNMGNAARTCNTCNGAY MGNAGYMGNCAYTCNMGNTCNMGNAGYMGNGAYMGNMGNMGNAARAARGARCAYMGNMGN AARTCNCAYMGNAGYMGNTCNMGNGAYMGNMGNMGNTCNMGNGAYMGN---GAYAGYAAR MGNAGYMGNGAYCAYMGNMGN---CAYAGYMGNAGYAARGAYMGNMGN------------ ------------------MGNGAYMGNGARMGNMGNGARAARMGNMGN---------AGY AGYMGNGAYMGNMGNMGNAGYMGNTCNMGNTCN---------MGNAGYMGNAGYTCNAGY CCNGCNAAYGCNAARGTNATHCARTTYGGNGGNAARGTNATHAARGCNGGNGCNAGYTTY GGNMGNCCN------GTNAAY------TCNAARCCNYTNACNTTYAARGARCARATGMGN CARCARYTNATHCARGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GAYAGYAGYGARAAYGAYGAYGAYGAYGGN ATHAAYGGNTAYTCNYTNYTNCCNCARGARCCNGCNGGNGTNGARAGYGAYTCNGAYGAY GARAGYTAYCAYAGYGTNCARAAYAAYGGNACNTCNGCNAGYAGYAAYGGNGAYGCNGAY TCNGARGGNGGNGCNACNGGNGGNGTNGCNACNTCNGCNTCNYTNTCNGCNGCNYTNTCN GCNTCNGAYGCNGGNMGNTCNGCNYTNTCNACNTGYYTNTCNAGYTCNGGNCAYCAYCCN GCNTTYTCNGCNAARTTYCCNGAYGGNAARGTNCCNTCNTAYYTNCARGTNCCNGARATG CCNMGNGAYAARCARGAYYTNYTNTGGAAYATGGAYGGNCAYGARAAYACN---ATHACN ATHGAYTCNGARAARGARTCNACNATHYTNMGNGCNATGTCNACNTTY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TTYAGYATHAAYYTNTGYGTNGGNCCNACNTAYGAYCAR GAYTGYGCNYTNCAYTTYAAYCCNMGNTTYGGNCARGGNTCNGTNGTNMGNAAYCAYATG CARGGNGGNGAYTGGGGNMGNGARGARACNGCNGGNGGNATGCCNTTYMGNMGNGGNGTN GGNTTYGARGTNCAYATGAARGTNCAYCAYCAYGGNTAYAGYGTNACNGTNAAYAAYMGN CAYTTYTGYGAYTTYAAYCAYMGNYTNCCNAARGARAGYGTNCARTAYATHTAYATHGAR GGNGAYGTNACNGTNAAYTTYATHMGNTTYCARGGNGCNGCNCAYTAYCCNAGYCCNGCN TAYCCNCCNGCNCCNGCNTAY---CCNTCNGCNCCNAGYTAYCCNCCNGCNGCNGGNTAY CCNACNGGNGTNCARTAYCCNCCNGTNCCNAGYTAYCCN--------------------- GGNGGNAGYGCNCCNATHTAYAAYCCNGCNGTNCCNTTYACNACNCCNATHCCNGGNGGN ATHTAYCCNGGNAARATHATHTTYATHAGYGGNATHCCNYTNCCNGGNATHAGYMGNTTY AAYGTNAAYYTNYTNTGYGGNCCNTAYGARTCNAAYGAYGTNGCNYTNACNTTYGAYGCN MGNTTYAAYTAYGGNAAYGAYMGNCARGTNACNGTNMGNAAYGAYAARCARAGYGGNAAY TGGGGNAAYGARGAYMGNGCNCARAGYTAYTTYCCNTTYAGYATHAAYGTNCCNTTYGAR ATHATGATHYTNGTNGARCCNACNGGNTTYAARATHGCNGTNAAYAAYCARCAYTTYACN GARTTYTAYCAYMGNYTNCARCCNTTYCARMGNGTNGAYCAYYTNATGGTNATGGGNGAR GTNMGNYTNACNCARGTNMGNTTYCARAGYGCNTAYCCNYTNCCNAAYTTYYTNYTNACN ACNTCNACNGGNYTNACNCCNACNYTNACNCCNACNACNYTNGCNACNATHGARCARAGY TTYATHGARYTNCARTCNTCNGGNGCNMGNGAYCCNGTNACNCARAGYGGNTTYGTNCCN CCNGTNGTNGAYCCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARCARGARATGAARGCNGCNGCNGAYMGNACNYTNAGYAARGTNAGYMGNGAR ATHCARGARGCNGCNMGNYTNAARGARACNATGACNGCNYTNCAYAARYTNMGNCARGTN MGNMGNGAYGCNGCNCARMGNMGNGGNCARACNGAYYTNGGNGARTCNAAYACNAGYTTY GGNGARAARATHACNGAYATGAARMGNYTNGTNGAYGGNCARYTNGARGTNTAYMGNCAR GARGARGCNGCNYTNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GCNTGGTCNAARGAYACN GAYTAYYTNTTYYTNMGNAAYAAYGTNCCNGAYTGYGAYAARYTNMGNAGYAARYTNAAR ATGAGYAARGGNGGNMGNGCNTAYTGYTGYCARTGYAGYTGGMGNAAYGTNAARGARYTN ACNGARYTNGCNGAYCCNCARATHAARTGGGTNTGYGGNAARCAY--------------- ---------------------------------------GTNYTNATHYTNTGYYTNTTY CAYTCNTAYYTNACNGTNTCNGARYTNACNACNAAYGARGAYATHAARGGNACNTTYACN GCNAARMGNGGNCARGARAAYTTYAAYCCNTTYAGYAARGGNTCNYTNYTNAARAAYTGY ATGGGNATHYTNTGYGGNCCNACNCARCCNAGYYTNYTNGAYMGNMGNGGNTTYGTNGTN CCNGAYACNGARCCNGTNTCNAAYACNCARAAYACNGGNACNAAYACNMGNGCNGAYMGN CCNGTNACNGTNGTNTCNGARGAYACNACNCCNGAYGCNGTNAARAARMGNGARATGATH AGYTAYCARTCNGCNGAYGGNTCNATHAAYAAYAARYTNCCNCCNGTNAGYGGNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNATHYTNTGYCCNTAYGARAARGCNCAY AARATHMGNGCNCAYMGNTTYTCNCARCAYYTNGCNAARTGYMGNAAYAAYCAYAARTCN MGNGARYTNAARTCNTGYTAYTTYAAYAGYGTNCAYCARATHCCNMGNYTNGARYTNGAY TAYCAYCAYYTNACNTGYCCNGAYMGNGCNTTYYTNGAYMGNGAYATGCARAARAARYTN ---------GARGARAAYGAYGAYAGYGTNTCNAARYTNMGNGGNMGNGTNGARGCNCCN CCNGTNACNTCN---CARYTNCARGTNGTNATHGCNGARGAYGAYTGGGAYAARGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARTTYTTYTCNCAYACNATHAARAAYTAYYTNCAYYTNCARGARATGCCNAARGARTTY YTNCAYCARATGGCNYTNGAYAARAAYCAYCCNGARAARGGNCCNTGGAARATHGAYYTN GGNCCN---AAYTAYCARCCNACNYTNATGTAYTGYAAYGAYAGYAARACNMGNCAYAAR GCNTGGMGNGCNTAYCARAAYMGNGCNTCNCAYGARCAYGCNCAYAAYTTYYTNAGYAAY CAYCARGCNATHAARACNATHMGNGAYCAYMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CAYYTNGARGAYAAYAAYYTNGTNAAYGTNCCNMGNCCNTGYCAY TAYMGNATHCCNAAYTTYGARGGNGCNGCNACNGCNAAYGAYAARATHGCNCARATGGAY GTNTTYAARACNGCNMGNGTNGTNAARGTNAAYCCNGAYAARCCNCARGARCARGCNMGN TTYATHACNYTNGAY------------------------------GCNAGYAARAAYYTN YTNGTNCCNACNACNCARYTNMGNAGYGGNYTNYTNAAYMGNGTNGTNCCNCCNGCNGGN GCNGAYAARGARAARYTNMGNTTYTGYTGYACNTCNCARGGNGTNAARGARCAYAGYACN GCNATHGAYYTNGARGAYMGNATHACNATHGAYYTNGTNATHGTNGGNAGYGTNGCNGTN TCNMGNGCNGGNTTYMGNATHGGNAARGGNAARGGNTTYGCNGAYYTNGARTAYGCNATG YTNMGNACNATGGGNGTNATHGGNGCNAGYACNCCNGTNATHACNACNGTNCAYGAYGAY CARGTNGTNGAYATHCCNGARGAYYTNGTNGARGAYCAYGAYYTNACNGTNGAYTAYATH GTNACNCCNACNGARGTNATHCARACNAGYTGYAARCAYGCNAARCCNGCNGGNGTNATH TGGAGYAARYTNGARCCNATHAARTTYTTYCARATHCCNGTNYTNMGNCARYTNMGNGAY YTNGARCAYGARAARGGNGTNGAYGTNMGNYTNAARGAYCARGARGAYGCNGAYGAYGAY CCNYTNGAYAARGARGAR---AAYCARCCNMGNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARGCNGCN GGNTCNGTNYTNTTYGARMGNCCNYTNGTNYTNMGNGARACNGTNCARTTYTAYYTNCAR TTYAARAAYTGGTGGTCNAGYCAYGAYTAYGAYMGNATHACNAAYATGGTNATHGARYTN TTYCCNGARYTNMGNGAYGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AGYYTNAGY TCNGCNGARYTNGARMGNATGMGNGARGARMGNMGNCARYTNGCNCARGARYTNMGNGCN GARCARGCNCARYTNGAYCARGTNAARYTNGAYAARAARGGNYTNGARGGNGAYGTNYTN MGNYTNAARATGGCNMGNGAYCARAAYAAYAARAARYTNGARGARYTNMGNGARMGNGTN GARAARAARYTNAARGARTTYGARAAYYTNCARGAYMGNTTYGCNGARGARGCNAAYCAR CARAGYGARTTYMGNCCNACNTCNGCNTCN------------------------------ ---TCNCCNAGYAARYTNMGNGTNGARGAYYTNGCNTCNGCNTCNTCN---------GCN MGNMGNYTNGCNYTNGGNAGYGAYGAYGARGAYGAYYTNTTYTCNYTNAAR--------- ------AARAARCCNGAYCCNTGGTGYGAYGTNYTNTCNGCNGAYGAYGAYTGGYTNGAR GCNGGNGARCCNGGNACNGGNMGNATHGCNCCNCAYGAYCAYYTNMGNAARGARGCNYTN ACNATHGCNMGNGCNAARACNTTYYTNCARAARCARAARMGNACNYTNAARMGNMGNCAR TCNGCNYTNCARGCNGCNAARYTNGARYTNAAYAARGAYATHGGNMGNGCNCARCAYGGN AAYTCNGAYGCNGGNAGY---CAYYTNYTNGAYGARGTNAARGARAGYYTNGARACNGAR MGNCAYCARATHGAYGCNYTNATGACNCARGTNAAYGCNGGNTCNMGNYTNATHMGNGAR AARGARGARAARYTNCAYCARATGGARMGNGARTCNTTYCARACNGCNAGYGARGGNGAR CCNGAYTTYTCNCCNTTYGAYMGNCCNTAYCAYMGNGCNAARATHCCNACNYTNGAYYTN AGYGAYGAYGARAGYAGYGGNATGGGNAGYAGYGAYGCNAGYATGGAYAAYTTYYTNTAY GGNAARCCNMGNCCNGGNGGNTCNGTNYTNACNAGYGCNGGNCARAGYGTNGGNGGNAAY GAYGAYYTNACNMGNGCNYTNTAYAARATHAAYTCNGARYTNTCNMGNGTNYTNGGNTTY YTNGAYAARGAYGGNGAYCAYCCNACNGCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AAYYTN CCNGCNMGNMGNCCNMGNATHGCNMGNYTNGAYAARAAYCARCARGGNACNYTNCARYTN AGYATHCCNMGNAGYTTYCCNMGNAGYCARYTNATGTAYYTNAAYGARATHGGNGCNGGN TGGTTYGGNCARGCNATHGARTCNGAYGCNGARAARATHGTNGARGGNGTNGCNAARAGY MGNGTNGTNGTNAARYTNATGAARGAYGARTCNTCNAARYTNGARCARAARCARTTYYTN GARGARATHGCNYTNTAYMGNTCNGTNGARCAYCCNCAYGTNYTNAGYYTNYTNGGNCAR TGYATGGARACNACNCCNTAYYTNGCNATHYTNGARTTYGGNCCNTTYGGNAAYYTNAAR ACNTAYYTNCAYAAYCAYMGNAAYGARYTNGAYTCNATGATHAARCAYCAYMGNCAYYTN AARTTYGCNYTNGAYGTNACNAGYGGNYTNGCNTGYYTNCAYGGNCAYGAYTTYATHCAY AAYGAYYTNTCNGCNMGNAAYTGYYTNGTNATGGCNGAYCAYTCNGTNAARATHGGNGAY TAYGGNATHTCNGARCAYYTNTTYAARGARGAYTAYTTYGAYACNGGNCARGARYTNYTN CCNGTNMGNTGGATGGCNCCNACNGTNTGGAARGAYATHGTNAARTTYGTNGCNMGNGGN CARTTYGTNCCNGTNGGNGGNACNTGGGTNGARATGGAYGGNAAYATHCCNAGYGGNGAR GCNTTYATHMGNCARTTYYTNTAYGGNCARGCNTTYTTYGARAARGARTTYGGNATHAAR TGYAARGARTTYTGGYTNCCNGAYACNTTYGGNTAYTCNGCNCARYTNCCNCARATHATG CARCAYTGYGGNATHCAYMGNTTYYTNACNCARAARYTNAGYTGGAAYYTNGTNAAYAAR TTYCCNCAYCAYTCNTTYCAYTGGGARGGNATHGAYGGNTCNCAYGTNYTNGCNCAYTTY CCNCCNAAYAAYGAYTAYTGYTCNACNGGNGAYGTNAARCARATGYTNTTYACNGTNAAR AAYTTYGARGAYAARGGNMGNTCNAAYTGYTCNGCNTAYYTNTTYGGNCAYGGNGAYGGN GGNCAYGGNCCNGARGARAARATGATHGARAARYTNCAYMGNYTNAARGAYTGYGAYGGN YTNCCNMGNGTNAARYTNTCNAGYCCNGAYGARTTYTTYTCNGTNYTNGARMGNGAR--- AGYMGNCARYTNTGYACNTGGMGNGGNGARYTNTAYYTNGARYTNCAYAAYGGNACNTAY ACNACNTGGGCNAARGTNAARMGNGGNAAYMGNCARTGYGARTTYYTNYTNCARGARYTN GARTCNACNTCNTCNYTNGCNGTNGCNYTNGGNAGYAAYTAYACNTAYCCNMGNGCNGAR YTNGAYCAYYTNTGGCARCARYTNYTNYTNAAYCARTTYCAYGAYGTNYTNCCNGGNTCN TCNATHACNATGGTNTAYAARGAYGCNMGNGAYATHTAYAARGARATHMGNAARACNGGN CAYMGNYTNYTNMGNAARGCNATHGARGCNYTNGGNGAYTGYCARTCNCCNGGNGGNGCN GAYTCNGAYGGNGARAGYYTNYTNGTNAAYACNCARGGNTGGGARMGNMGNGARGTNATH GARYTNCCNCCNTCNGCNTCNAARMGNAARAARACNTTYYTNGARGAYTTYGARGGNAAY CARYTNGCNATGGTNAARGTNCCNCCNTAYGGNYTNACNACNYTNGAYACNTGYGARGTN TCNGGNGTNACNGTNAGYMGNCARGAYGAYACNATHGTNATGACNAAYGGNYTNYTNMGN GCNGTNATHGAYCCNYTNGGNMGNGTNGTNTCNYTNMGNYTNCAYGGNAGY--------- ------GAYYTNGARGCNATGAAYCCNGARCAYCCNGGNAAYCARYTNYTNYTNTAYGAY GAYATGCCNYTNTTYTGGGAYGCNTGGGAYATHATGGAYTAYCAYYTNGARACNMGNAAR CCNYTNATHCARMGNTCNATHGTNMGNGAYAGYGAYAAYCCNYTNMGNGGNTCNGTNGAR GTNAARYTNAARATHAGYGAYAGYAGYTAYYTNMGNCARYTNATHGTNYTNGAYGCNGGN AGYCCNTAYYTNMGNTTYGAYYTNGARGTNACNTGGCAYGARAAYMGNAARYTNYTNAAR GTNGARTTYCCNACNACNGTNCAYGCNATGGARGCNACNTAYGARATHCARAAYGGNTTY YTNMGNMGNCCNAAYCAYTAYAAYACNTCNTGGGAYTCNGCNMGNTTYGARGTNTGYGGN CAYAARTGGGTNGAYATHTCNGARCAYGGNTTYGGNGTNAGYGTNYTNAAYGAYAGYAAR TAYGGNCAYTCNACNGTNGAYGGNGTNATHMGNACNTCNYTNYTNMGNTCNCCNAARGCN CCNGAYTAYAARGCNGAYATGGGNTTYCAYAARTTYTCNTAYGCNGTNATGCCNCAYAAR GGNAGYTTYGCNGAYGCNGGNGTNGTNCARCARGCNTTYMGNYTNAAYCARCCNGTNACN GCNYTNMGNGTNGGNGGN------AGYCCNMGNGGNGGNGGNGTNGGNAGY---YTNTTY TCNGTNAGYACNCCNCARGTNGTNYTNAGYTGYGTNAARATGGCNGARGAYGGNAGYMGN ACNYTNATHYTNMGNTTYTAYGARGCNTTYGGNGGNMGNGCNAAYGTNGARGTNGCNACN CCNYTNTCNGTNTCNGARGTNCAYMGNTGYAAYGGNYTNGARCAYYTNGAYGAYAGYCAY GAYACNGGNYTNGCNYTNAARTCNMGNYTNGARGGNGGNMGNTGYACNATHTCNTTYMGN GCNYTNCCNTTYCARATHATHTCNYTNMGNATHAGYYTNGGNMGNTGGATGACNGCNGGN GGNGARAARGARGTNGARGGNMGNGGNCAYYTNYTNCCNGARGAYCCNTGYGGNAARGAR GAYGTNAARGGNTTYGCNMGNYTNCCNCARGAYTGGGTNGGNGTNYTNCAYTAYCCNGCN GAYATGGAYAGYCARACNGGNGARACNACNACNGCNGAYTGYCCNCAYGTNATGGAYMGN GTNCARAARGCNYTNATGTTYGGNGCNTCNGCNATHATHATHYTNACNYTNAAYCCNMGN ATHATGAARGARTTYGAYGTNGCNCARYTNGTNTCNCARCCNATHGTNYTNATHGARGAR GCNGARAAYATHACNGCNATHYTNACNYTNYTNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNGCNGARGARGTNGAYTAYACN TTY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARCAYTCNGCNGARGGNYTNACNATGTAYTGY YTNTCNTGYAARYTNCCNGTNTGYTCNTCNTGYGCNCARGAYGGNMGNCAYATGACNCAY GARGTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYAARMGNACNGTNCARAAYAARAARTCNTTY GTNTGYCCNAARTCNACNCARTGYGARATHAAYCCNTTYAAYMGNAARAARTGYCCNGCN TGYMGNTTYAGYMGNTGYYTNACNATGGGNATNAARATHGARGCNATHMGNAARGAYMGN ACNMGNGGNCCNAAYAAYAGYMGNGTNCAYAARCARYTNGTNGCNATHYTNAAYCAYTCN AGYAAYAARCARACNACNGARGGNGGNGTNCCNCAYATHCCNGARYTNYTNMGNGAYATH ATGAAYYTNGARCCNYTNYTNTCNGAYGAYGAYATHCCNGCNGAYGCNATHATHGARAGY AGYGAYCCNGAYAGYGCNYTNTAYAGYTAYATGATGCARYTNGCNGARGTNMGNYTNTAY AARYTNGTNMGNTGGGCNMGNAAYYTNCCNCARTTYGGNGCNATHTCNACNGAYGAYCAR ATHYTNYTNYTNCARAAYTGYTGGGCNGARYTNATHGCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNCAR YTNTCNGCNGARAARTCNACNGCNACNGTNTTYACNTCNTTYTCNGGNGARGCNAARACN GARYTNGAYGTNCARATHMGNGGNACNAARATHCCNACNGTNMGNMGNCCNAARATHYTN GGNGTNACNTTYGAYAAYYTNGCNACNTTYTCNGCNCAYGCNGARACNATHAARCARAAR GCNGCNAARMGNAAYAAYGTNYTNAARTGYYTNGCNGGNAGYNNNTGGGGNAARGAYAAR GARATHYTNACNACNACNTAYAARGCNATHAGYMGNCCNATHYTNAAYTAYGCNGCNCCN ATHTGGCCNYTNYTNAGYAAYACNAGYTGGGARAARYTNCARTCNACNCARAAYGCNGCN YTNMGNACNATHACNGGNTGYCAYAARATGAGYAGYATHGAYCAYYTNCAYACNGARACN AARATHYTNCCNGTNMGN------------------------------------------ ------------------------------------------------------------ ---------------------------AARCCNCCNACNAAYYTNGARGARTTYYTNGCN GCNGARGGNYTNGARGAYTGGCCNYTNCCNATGGCNYTNGARGGNCCNYTNGAYATHAAR TCNGARGGNYTNTTYATHGGNGAYCARTCNGAYATHGCNCAYATHYTNAARGARGCNGCN CCNGTNGGNATHCAYATGYTNGAYGARATGGARTCNMGNYTNTCNGAYYTNGARGCNACN YTNGAYTAYTAYGCNAGYMGNATHGTNACNGAYGAYAARMGNCCNTCNMGNATGGCNGAY MGNYTNTTYCAYTCNCCNTCNMGNACNTTYATGACNGARATGTCNCARTCNGAYGCNGTN YTNTCNCAYMGNAGYTCNAARGGNCAYAARAGYGTNGAYYTNATHGAYACNATGATGGAR ACNMGNAARAARAGYYTNGAYTAYTAYACNTTYTCNGGNTTYMGNCAYGGNGARYTNATH GARYTNCCNTCNCARYTNGARGCNCCNCCNATHYTNCAYATHGTNACNAAYGCNCARGAY TTYAAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYGGNATHTGGTAYYTNTTYATGGCNACN TTYGCNCCNGCNAGYYTNTCNTCNATGYTNGGNCCNATHTCNYTNCCNGGNACNTTYATG GGNAARACNTAYCCNAAYTTYTGYTTYGTNYTNTGYGTNGTNACNGTNGTNATHCAYTGY YTNGARGCNGCNTAYGCNGGNAARATGTGYCARGAYMGNGARYTNAGYGTNGGNGTNTCN ATHYTNTGGGTNYTNCARACNTTYGTNTAYGGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNACNGAYGGNYTNYTNGAYGAYGCNYTNACNGAYGCNGTNCAYGGNYTN GTNGARMGNGGNGARGCNTCNACNMGNGCNGCNGCNGCNYTNGTNGAYTCNCCNACNYTN GARAAYATHMGNCAYMGNYTNGCNCARATGCARMGNGARCARACNGARATHMGNCARMGN TGGACNTCNYTNAARTTYGTNGARCARAARCCNAARTCNMGNTTYTTYACNACNAGYGAR GTNYTNAGYGAYMGNCCNMGNGARCCNCCNGCNATHGARGTNACNMGNATGTCNCARTCN ACNCARCCNACNTCNGGNCAYMGNTCNTAYACNAARGAYGCNACNGARGARCCNYTNATG TTYACNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY ACNYTNTCNAARACNAGYATGYTNGTNCCNAAYGCNGCNGTNTTYGCNGARGCNGCNGTN MGNACNYTNGGNTAYTCNGCNMGNACNGCNGGNTAYTTYCCNCAYACNGTNCARYTNTGG YTNAGYCARATHATHCCNGARTGGYTNTGGATGTGGGGNGCNGARAARYTNAAYAAYGCN YTNMGNCARCARGCNYTNMGNMGNATGGCNGCNGCNTTYYTNYTNGTNGCNATHTCNYTN GTNGGNCARTGYCARTTYGAYGGNTTYGGN------------------------------ ------MGNGAYMGNGAYMGNAAYMGNGARMGNGAYMGNGAYMGNGGNMGNGAYCARACN GCNGARGGNTGYTTYGGNAARGTNATGGAYATHTTYTTYATHYTNGAYTCNTCNTCNTCN ATHTAYATHAAYGAYTAYMGNCARCARCAYCARTTYGTNMGNGARGTNGTNAGYMGNTTY GAYGTNTCNCCNMGNACNACNMGNGTNGGNATHYTNACNTTYAGYGAYGAYTAYGARMGN CCNCCNYTNGGNYTNAAYMGNGCNCARTCNAARGGNGAYGTNYTNGCNAGYATHGAYGAR ACNAAYYTNCCNTAYMGNACNGGNATHACNAAYACNGAYMGNGCNATHMGNTAYGTNMGN GARAAYAAYGARTTYMGNMGNGAYATHACNAARGTNATGGTNATHYTNACNGAYGGNGGN TCNMGNTCNCCNGGNGCNACNTCNMGNGARGCNGARYTNGCNMGNAAYCARGGNTTYTAY ATGTTYGTNGTNGGNGTNGGNCARTAYYTNGAYGARMGNGARTGGNNNGCNATHGCNTCN GAYCCNGAYGAYAAYTTYATHTTYAAYATHACNAAYTTYMGNTAYYTNGAYAGYYTNAAR TTYGTNATGCCNCCNMGNGCNTGYACNYTNCCNCCNATHATHGCNGGNGGNAGYTGYACN GTNAGYGARCCNGCNGAYGTNTTYTTYGTNGCNGGNCCNGGNGGNTCNCARGAYGCNATG TTYYTNATHGAYCAYTTYGTNGARMGNACNMGNGAYCCNTTYGGNYTNGTNMGNGTNAGY TTYATHATHGAYAGYTGYACNGAYGGNGARAAYGTNGARYTNACNGAYCCNGGNMGNTTY ---TGYGAYMGNTTYGCNGAYYTNGGNGCNGCNACNAGYGARACNTAYGTNGAYYTNATH ACNMGNATGMGNTCNYTNGCNGCNCARACNMGNAAYTCNMGNGTNGCNAAYCARGTNGCN GTNATGTTYATHGAYAAYGARTCNATGMGNYTNAAYMGNTTYGGNATHGTNAAYGARATH GARMGNGCNAARGCN---GAYMGNATHAAYYTNATHGTNGTNGAYYTNGGNGTNMGNCAR TTYGGNAGYACNATHGCNGGNYTNCCNGAYMGNCCNGARGAYYTNATHMGNTTYCARGGN GGNAGYATHGCNGGNCARMGNCARTCNCARGARMGNATGATHGAYMGNACNTGY------ ------------------------------------------------------------ ---------GAYGAYTTYGARAARYTNGAYGCNCCNGGNGCN---------TTYGAYACN GAYTCNYTNAAYGARGCNTCN------------------TTYCARGAYAARGARGTNACN TCNACNTCNAAYGTN------GCNGGNGARGAYGARGCNGARGARGAYMGNTAY---GCN GCNGGNGCNTCNGARGCNGARGCNATHGCNTCN------CARCCNYTNATHTCNTGGGAY GAY---------------------GGNYTNGGNGAYGCNGTNGARGCNTCNCARCCNGCN ------------TCNGCNCCNGTNCCNGAY---GAYTCNTTYGAYCCNYTNGCNGAYTTY ---------------AGYMGNCCNGAY------CCNGARCCNCAYTTYACNAGYTCNGTN ATHCCNTCNAARTCNGARCCNGAY---GTNCCNGARCCNCARCCNTCNAARATH---TCN GAYAGYTTYAARACNTTYGARGARAARGARAGYAARCARAGYATGGCNCCNGCNAARGTN GTNTCNGARGARGCNCCNAARACNGAR------------GGNTCNTGGYTNAARGGNGTN GAYCCNMGN------------GARGARTCNGARGARAARGTNYTNGTNGAYYTNATHTAY TGGMGNGAYGTNMGNACNACNGGNGCNGTNTTYGGNACNATGATGTTYGTNYTNYTNAGY YTNGCNTTYTTYTCNGTNYTNAGYGTNGTNGCNTAYYTNAGYYTNGCNGTNYTNACNGTN ACNTTYACNTTYTGYGTNTAYAARAARGTNATGGCNGCNGTNCARAARTCNAAYGAYGGN CAYCCNTTYAARGAYTAYYTNGGNATGGARATHGCNYTNAAYGARGAYCARGTNAARACN GTNGTNCARTCNGTNYTNMGNAAYATHAAYGCNACNTCNCARGARYTNMGNMGNYTNTTY YTNATHGARGAYATHGTNGAYTCNATHAARTTYGGNYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGGAGYGTNCAYCCNTGY AARGAYTCNAARGAR------ACNTTYAARYTNGCNGCNMGNGARAARATHCARTGYYTN YTNGAYMGNTAYCARAGYAGYYTNTTYYTN---------GAYMGNCCNAGYCCNCCNGAR GAR---------------------------GARGAYCCNCCNGAYACNGTNGTNTAYCCN YTNYTNCARATGGGNCCNYTNGGNATHGCNAAYGAYGARCARGCNACNYTNAAYYTNYTN TGYMGNACNAARMGNMGNGAYGARATHYTNYTNGCNTCNGGNTAYTTYAAYYTNACNGAY AAYTAYATGAAYGTNATHGTNGGNGARTCNYTNGCNAARTAYAARATHYTNATGGCNTCN CCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GTNAAY AARCARTCNAAYGARYTNAARAGYMGNYTNTCNTCNGCNGARACNMGNTGYCARYTNYTN GARAARCARYTNGARTAYATGMGNGARATGGTNMGNAAYGCNGAYAARGAYMGNMGNGAY TTYATGMGNAARTCNATGCARGTNCARTCNGARMGNGARGCNGGNCCNGAYYTNAARYTN CAYYTNGAYMGNYTNAAYGARYTNGARMGNGARCAYGCNMGNYTNACNGCNACNCARAAY YTNGCNGAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GGNYTN ATGGCNCCNATGATGCARAAYAARATHGARTCNGTNYTNMGNGAYAAYACNAGYCAYAGY ATGAGYCAYTCNAGYGAYAARCCNACNTCNTCNAGYCARAAYTCNCCNCARGARAGYMGN GGNGARMGNTTYGTNCARTCNTCNGAYCARGCNGAYGAYGGNGARMGNACNGGNTCNTCN AGYGARCCNTCNYTNTCNCCNTCNTCNAGYGGNGGNAGYCAYGGNMGNAARMGNATHYTN GGNMGNCCNMGNGGNMGNCARGARGARATGGTNTCNCCNGCNATGCCNTCNTCNTCNGTN TCNTCNYTNTCNTCNTCNAARGGNTCNAGYCAYCCNAGYAGYTCNTCNMGNGARACNGCN MGNACNGGNCARTCNCCNGGNCAYGARGGNGCNMGNACNCCNCAYAARAGYGGNAGYGGN ------------------------GTNGAYAARTCNGGNAARYTNTCNGCNTAYGAYTTY CCNGAYGAYAGYCCNGAYGARGARCCNGTNAGYTAYATGGCNYTNGGNTCNGGNMGNGGN GGNMGNAARTGYCARGTNGAYAGYTCNGARGGNAARTCNGGNTCNGGNTCNGGNCCNGAY ACNCARGCNCARGAYGAYAGYAAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGTGGAAR GCNMGNGCNTCNMGNAGYGGNAARMGNYTNYTNAGYGCNGCNMGNMGNCARTTYGCNACN GAYACNGCNGGNAARCCNGCNACNCCNCCNCCNCCNCCNCCNCCNCARGCNGGNGGNGGN GGNGGNYTNYTNAARATGYTNGGNGTNGGNACNATHYTNGGNGGNGGNGGNACNGTNGGN TAYGCNTGGTAYGAYCCNGAYTTYMGNAARATGYTNGARGAYAAYGTNCCNTAYGCNAAR GARGCNYTNGAYAGYATHYTNCCNCCNYTNAARCCNGCNACNCCNCCNGCNTCNTCNCCN AARGARGTNTTYAARCCN---YTNAAYATHGGNGARAARAARGGNAARAARGARCCNGTN ATGTCNTCNAGYAARCARGTNCARGARGGNACNGCNGCNGCNCCNGCNGTNGCNTCNGCN GCNATGACNGARACNGCNACNCCNYTNGTNGAYGARAARAARAARMGNMGNGAYYTNGAR MGNAARAARCARGARGAYGAYMGNGCNGARAAYGCNGCNYTNGARGTNGTNYTNCAYAAY CARATHCARAAYGCNAARAAYYTNAGYAAYGAYGCNGTNMGNGCNCARGARAARGTNATH TCNACNACNCAYAAYTAYACNCARYTNYTNAARACNGCNATGGAYGAYAAYAGYAAYATH YTNCARAARGAYTCNCARTGGCARGCNGTNMGNATHGCNAGYCARGARAARGARGAYGCN AARACNCARGCNTGYCARYTNATGAARAAYGCNAARGARAGYYTNGARAARYTNAARCAY ACNATHGAYGARGGNAARAARAAYAARGTNACNCAYAARAAYTCNGCNYTNYTNCCNGCN GARAARGAYYTNAGYAAYTGYAAYTCNGARYTNGGNTCNTCNGCNTCNATGGTNCARCAR GCNGARGCNGARGCNAARGTNYTNGTNAARTAYAARGAYYTNGTNGARAARGGNMGNCAR CARTTYCARCARGARYTNGARGGNATHATGCCNAARYTNAARTGYGGNACNTCNGGNGCN AARYTNTCNGARGAYGARYTNAAYATGYTNATHGCNCAYGCNCAYMGNMGNATHGARCAR YTNCARAARCARATHGCNGARCARYTNGTNYTNGARCARCARMGNATHGAYAAYGCNYTN GAYGCNCARMGNAARGARGAYTCNTTYYTNACNTCNCARGARGTNAARCARGARGCNGAR MGNATGMGNGCNGARTTYAARYTNGARAARCARAARTGGGARAAYGAYAARGARGGNGAR ATHGARGCNAARATHMGNAARCARYTNGCNYTNCARGCNGCNGCNCAYAAYGAYCAYGTN AAYGARGTNYTNTGYAGYCARGARAARGAYYTNATGGCNMGNTTYGARMGNGARYTNCAY ACNMGNATHYTNTCNGARMGNCARGARTTYCARCAYGARATHGARGGNTGGATHGGNMGN YTNAARGGNATHGARTCNGCNATHGAYGCNMGNGCNTCNCARGARAARAAYGCNMGNACN GCNCARGAYYTNTGGYTNGCNTGYATHGCNYTNAAYTCNGCNATHCARTAYGGNAAYGAR AARCCNGARGAYTGYGTNCAYCCNYTNGTNCARGARGTNGARAARGTNMGNACNACNGCN AAYAARAAYCCNTTYGTNGARACNGTNYTNTGYACNATHTCNGAYGARGCNYTNAARMGN GGNGTNTGGACNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GGNYTN GAYGAYCCNACNCCNGTNGAYGAYACNGAYACNCAYAGYCARGTNTCNYTNGGNAGYAAY TCNCCNAGYCARGARTTYAAYGAYACNTTYGARGGNYTNGARGGNGCNACNGGNGGNAGY GAYTAYCCNGAYTAYAGYAGY------AGYGCNCCNTAYACNMGNGTNTCNCAYACNTCN GARTCNTCNTCNGAYTCNGGNTTYCCNTAYCAYTCNGGN--------------------- ---------TCNTCNTCNTAYAGYGGNAGYCCNAGYTCNAAYTAYGGNGGNAAYTTYAGY AGYAGYAGYAAYGAYACNGAYCAYAAY------------CAYAGYATHGCNCARCAYGTN GCNCAYAAYCAYACNTAYCCNACNCARCCNGGNCARACNCCNMGNGARGTNAARAARTAY GCNCARAARGAYCCNTCNAARAARTCNGGNMGNACNMGNGAYCAYMGNMGNGCNGARGAR YTNAARGTNCCNTTYACNGTNGARGARATHATHGARTCNCCNGTNGARACNTTYAAYGAY ATGYTNACNAARTAYAARYTNACNGARGCNCARYTNGCNYTNATHAARGAYATHMGNMGN MGNGGNAARAAYAARATHGCNGCNCARAAYTGYMGNAARMGNAARGTNGGNGTNATHYTN ACNYTNGARGAYGARATGGGNGARYTNCARMGNCARMGNGAYMGNYTNMGNTCNGARMGN GTNCAYATGGARCARGARACNMGNYTNATGAARGARMGNTAYTCNCARYTNTAYTCNCAR ATHTTYCARAAYYTNMGNGAYGARCAYGGNCARCCNTAYGAYCCNAGYAGYTTYACNYTN CARCARYTNACNGGNGGNGAYATHATHYTNGTNCCNMGNAAYATHTCNGTNCCNACNGGN GGNTCNACNGGNTCNGCNGCNTCNTCNCCNTCNACNYTNTCNAGYTCNTCNCAYTCNTCN TCNGCNTCNAARGCNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CCNCAYCCNAARGTNYTNTCNAARCAYACNMGNACNAAYTGGGAYCAR TTYTAYAARTCNTGGTAYTTYTTYTTYTTYTAYYTNCCNTGGGTNCCNGARTGGTAYGTN AGYYTNACNGAYATHAAYGTNYTNAAYATHATHTTYYTNAGYAGYGCNGTNGGNGTNCAR ACNGGNGCNACNACNATGGARGAYYTNGARGCNTAYAARTAYYTNTTYMGNACNCCNGCN GCNYTNACNCCNCCNATGAAYTAYYTNMGNGCNGCNYTNMGNTAYGAYTCNCCNCCNCAR YTNTAYCARAARGTNACNGTNCCNATGYTNYTNTTYTGGGCNGGNMGNGAYCAYGCNYTN GARMGNCCNCARGCNGARATGTGYCAYGAYTAYGCNAAYAAYYTNACNATHAARTAYYTN GAYAARTCNAGYCAYTGGGTNCAYATGGAYGARCCNGARGARGTNAAYAARYTNATHACN GARTTYATHGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNTGYYTN---GGNAGYTCNGCNGTNGAY CAYCAYCAYCCNAARCCNMGNGARYTNGTNGARAARTGGGGNGCNCAYATGAAYCARYTN CCNGTNCCNGARGGNCCNTGGGCNGARYTNCAYCARAARMGNCARGCNMGNGGNAAYATG CARYTNGGNGCNTCNGCNGTNGCNYTNATHYTNACNGTNGCNACNYTNTAYACNATHGGN ------------------------------------------------------AGYYTN AGYGTNCCNGCNAARYTNMGNMGNYTNTAYGCNYTNAAYCAYACNYTNMGNCARAARTGY GTNACNGCNCARYTNACNAARCARGTNGCNGTNGTNCAYCCNGCNACNTGYTTYCARGAR MGNYTN---GARGCNATGTTYGAYGTNGARGARGARYTNTAYCAYMGNGTNTGYGCNYTN GGNTGYYTNYTNTGYCAYCARYTNYTNCARTCNGCNATHGAYAGYACNAAYYTNTCNYTN GTNTCNGARGAYTCNACNGTNGARGAYATHATHMGNGCNAARMGNATGGTNGARTTYATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARMGNAGYYTNMGNATHGCNGCNGARGARAARYTNMGNMGNCAYYTNGTNGAYYTN TAYAAYAAYCCNGAYATHAAYGCNGARYTNMGNGARMGNYTNCCNMGNTCNAARAARGAR GAYCCNTTY--------------------------------------------------- ------------------------------ATHAGYTCNGARTCNAARTCNATGGAYGAY YTNGAYYTNTAYGGNCAYGARTGGGCNMGNTGYYTNCARAGYTGYTGYCARGTNATHMGN GARGCNAAYGARYTNTTYAAYACNGTNAGYAGYTCNAGYGTNTGYAAYGARGTNYTNMGN TGYAGYCARGGNACNCARTAYGTNGTNGGNYTNGTNGARGTNTAYMGNGTNGTNTGYMGN ATHATGACNTCNATGAARGCNACNGCNATHTCNACNGAYGARYTNGARCARACNYTNAAR GARATHGAYYTNGCNTGGAAYAAYYTNACNGCNTTYYTNGTNGGNGCNTCNYTNYTNCCN GARTCNAGYTCNYTNATGTTYGCNCAYACNATHGTNAARTCNGAYAGYGARGARGGNCAR MGNMGNGCNTGYGGNYTNTGYYTNYTNGAYGTN--------------------------- ---------------------------------------ACNGARGARTCNGARTGGGAY GCNTAYYTNATGTCNCARYTNAGYGARYTNACNGCNAAYTGGATHGCNCAYGARTGYACN TCNCCNGAYGGNGARMGNGARMGNYTNACNTCNYTNGTNCAYGARTGGTAYGGNGTNCCN ACNCAYACNGAYYTNGTNMGNGARGARATGAGYGAYGGNGAYGARGAYGARAARAARGAR AARGGNCARGCNAARAARAARTGGAARAARAARGARGARTCNYTNYTNGARMGNGTNTAY AARATGCARAARAARCCNCCNGARGCNACNGAYCCNTAYTCNGAYGAYAAYAARGCNCCN TTYTAYMGNCARCCNGCNGGNATHMGNAARYTNAARAARAGYGARGARAARGARGARCAR GGNGCNATHAAYAARACNGCNCAYAAYATHGTNGTNAARAGYTAYMGNGARACNCCNCCN YTNACNYTNMGNGAYGTNATGGAYCCNMGNGTNGGNGARAARYTNTAYGARACNGAYAAY YTNTAYGARCAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGMGNCARAGYGGNAAYTCNAGYTTYGARTTYTTYGARCCN GAYCARYTNGARAARGCNGGNTGYGTNGAYAARYTNATHTCNGTNTAYGGN---AAYAAY CCNCAYAARACNGGNGGNGARACNTGGTCNTGYGCNTGGGCNCCNGAYYTNTCNTAYTTY GGNTGGTCNTGYGGNTAYMGNATHGTNCAYYTNATHCCNTGGGAYGCNGGNAARMGNAAR AARCARGAYCCNGCNGAYCARGCNGGNYTNTCNGCNMGNCARTAYCAYYTNATHGAYTGY GGNGAYYTNGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARCCNGARGAY GARGARGARMGNYTNGTNMGNACNATHATGMGNACNACNYTNMGNGGNAAYTCNGAR--- AGYCARCAYGCNACNTAYGGNACNAGYTCNCARCARGARTCNCAYMGNGARGCNGARGAR CAYACNYTNAAYCAYACNGGNGCNGGNCCNCAYCAYCAYATGACNCAYACNACNGAYMGN MGNCCNATGTCNTCNMGNTCNAAYCAYTCNGGNGTNGGNGTNATHTCN------MGNGTN CCNGTNGGNCCNTCNGAYACNACNAARAARACNTAYAAYGGNGAYYTNYTNGARAARMGN TCNCAYGTNTTYACNGARCCNAGYAARCCNTTYACNCCNMGNACNYTNAARAGYACNMGN GARTCNMGNYTNAARGARTAYAARTAYTAYAAYGCNCCNAAR---GTNCCNGCNGGNTCN AARATGAAYGGNGCNCCNMGNCCNAARCCNMGNCCNMGNGGNAGYCARTCNAGYAARGCN GGNGAYTCNGCNTCNGGNGTNCARATGGAYCCNGGNGAYACNGARCARYTNACNGARACN ATGYTNATGGAYATHACNYTNMGNACNMGNGAYGARMGNTCNCAYGGNMGNMGNGGNTCN CARGTNCCNCCNYTNGCNATHAGYGTNGAYACNGAYCAYATGCARTGGYTNCARGARCAR GCNTCNAARGCNCARGTNMGNGCNMGNTCNAGYGGNCARYTN---MGNTCNTCNYTNAGY TCNGARCAYGGNAGYGCNGGNGARCCNGGNMGNGARGGNAAYGCNTCNGTNTCNGGNMGN AARGCNAGYGTN---AARGAYGARGARCARAARTAYYTNACNTTYGCNCARGARGTNACN AAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNATHCAYGCNMGNTTYGCNAGYTAYCARGTNCCNMGNCCNTTYGTNTCN--- ---CARTCN------------------------CARCARAAYGAYAAYGCNGCNYTNATH GARAAR---YTNGARAARGARAARGARGAYAAYMGNMGNYTNCARCARCARYTNGAYGAR AARGAYMGNMGNATHAARGARYTNGARMGNGARYTNGAYYTNYTNAAYAARGARTGYGAY GCNYTNGAYGARGAYAAYATHAARYTNCARGARGARAAYAARGCNYTNATHMGNGCNATG TCNAARYTNGGNTCNAAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNACNGTNCCNCARATHGARYTNTCNTCNMGNGAYGCNYTNATHGAYGARCAR GTNCARATHMGNATHTCNGAYYTNGGNCARGGNCARAARGTNACNGTNCARGTNTTYYTN CARGARGCNCARAARCARTAYGGNTCNTGYGCNCAYTAYATHGCNAAYGGNGARGGNAAY GTNGAYACNTTYGTNGAYCCNTGYTTYGGNGGNTCNTTYACNGGNACNGARCCNATGGGN YTNTTYTGGAGYATGAARCCNACNCCNGGNACNAARCCNGGNMGNYTNATHAARAAYGAY GTNACNACNCCNTTYGARGTNACNATHGCNGTNMGNGAYAGYTTYCARGARTTY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CCNAGYTTYGAYATGCCNATGGTNAAYGTNACNGTNACNGARAARATG ACNGCNGTNYTNCCNTGYTCNGTNAARTAYYTNGGNGTNCAYCARGTNGTNTGGACNGAY CARTTYTCNACNYTNYTNACNTTYGARGAYMGNMGNATHATHGAYGAYGARMGNYTNAGY GTNGARMGNCCNTTYACNAARGAYTGGAAYYTNCAYATHMGNGAYGTNAARGCNGGNGAY TCNGGNATHTAYAAYTGYCARATHAAYACNATGCCNATHAARATHAARACNGTNAAYYTN AARGTNCARGTNCCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNCCNAAYGTNGCNATHMGNGARGAYGAYGTNYTNATHTGYGCNTAYCCN AARTCNGGNACNCAYTGGYTNTGGGARGTNACNTCNCARYTNYTNGCNGGNAARGTNGAR ACNGTNCCNAGYTGGAARTCNMGNTAYATGYTNGARYTNGCNCCNGARTCNAAYTTYMGN GAYGAYCCNTCNCCNMGNGTNYTNAAYTCNCAYGTNTAYTAYAGYGAYYTNCCNMGNAAR GCNYTNGARAARAARGCNAARATHATHCARATHTTYMGNAAYCCNAARGAYATHGCNGTN TCNATGCAYCCNTAYTAYTAYGTNCARTAYGTNCCNATHTCNYTNAARCARGAYYTNGAY ATGAARGTNAAYTGGGCNACNTCNCCNAAYTCNGCNCCNAARCARGAYACNAGYAARCAY TTYCAYGTNTTYGTNGGNGAYYTNAGYCCNGAYYTNGARCARCAYCARYTNMGNGARGCN TTYCARGTNTAYGGNGARATHTCNGAYTGYAARATHATHMGNGAYTCNCARACNYTNAAR TCNAARGGNTAYGGNTTYGTNTCNTTYGTNAAYAARTCNGAYGCNGARGCNGCNATGCAR GGNATGAAYGGNCARTGGYTNGGNTCNMGNCCNATHMGNACNAAYTGGGCNACNMGNAAR CCNCCNGCNCCNATGYTNAARGARAAYGCNAARCCNCARTCNTAYGAYGARGTNTAYAAY CARTCNAGYTCNACNAAYTGYACNGTNTAYTGYGGNGGNGTNAAYAAYGGNYTNTCNGAR GARYTNATGMGNAARACNTTYAGYTCNTTYGGNACNATHCARGARATHMGNGTNTTYAAR GAYAARGGNTAYGCNTTYATHMGNTTYTCNACNAARGARTCNGCNGCNCARGCNATHTGY TCNATHCAYGGNACNACNATHAAYGAYCARCCNGTNAARTGYTCNTGGGGNAARGARTCN AAYGAYAGYTCNGCNCCNAGYTCNCARACNTCN---------ATHACNGTNAGYNNNNNN CCNCARCARCARACNGTNGCNGCNACNCCNGCNGCNGCN------TAYGGNCARTTYTAY AAYATGGGNTAYTAYAAYGGNGCNCCNTAYGCNGCNACNCCNGCNGCNTAYCARGCNCCN GTNCARGCNCARGGNCARTAYATHCCNGCNGGNGTNGGNCARTGGCCN---GCNGCNTAY AAYTAYCARGCNTAYGGNTCNATGAAYGTNCCNATGGGNCARTAYGCNGGNYTNCARATG CARCCN---CCNCARCARCARCARTTYAAYGGNCARGCNCARGGNATGATGGGNTAYCCN ATGCARCARGGNATGTCNMGNTCNACNGTNMGNTAYGARGTNYTNCCNTCNGARGARCAR AAYGTNCCNGCNGARCCNGTNGCNATGGCNATGGTNGTNCCNCCNCCNGARTAYACNGAR AAYGCNGTNATGGARCARCARGGNGAYACNCCNGCNTTYGGNCCNGCNAARYTNCCNAAY TAYGARGARGCNACNACNYTNCCNACNTAYGARGARGCNGARCARGCNAARMGNGARGAR GARACNGGNCARTCNCARTCNGCNGGNCARYTNGARATGGGNMGNYTNGCNGGNYTNGAY ACNATGTCNGARGTNGCNATHGGNACNGAYGGNATGTTYATHTGYACNTTYYTNATHTCN TTYATHTTYAAYTGGYTNGGNTTYYTNYTNTCNYTNTGYYTNTCNAAYACNGTNGCNGGN MGNTGYGGNGCNYTNTCNGGNYTNGGNYTNTCNATHGTNAARTGGGTNGCNATHATGAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TTYATGTTYGCNGGNCAYAGYACNACNTCNTCNYTNYTNACNTGGGCNYTNTAYYTNYTN GCNAARCAYCCNGAYGARCARGARAARGTNTAYAAYAAYGTNMGNTCNGTNYTNGGNGAY AARACNCARGTNACNTGGGARGAYATHGGNAARATGGAYTAYYTNCAYTGYGCNYTNAGY GARACNYTNMGNYTNAAYCCNCCNGTNTCNGGNYTNCARMGNGCNGTNAAYAARCCNACN GARATHGAYGGNACNACNGTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNGAYYTNGARAAYMGNGAYCCNAAYAAYYTNAAYGAYCAYGTNMGN GTNGCNTGGGAYGAYGTNTTYGGNGARCCNGAYGGNGCNCAYTCNATHAARTGYGTNTGG GTNAAYTCNTAYMGNTGYTTYAAYTGYTCNAARAAYTGYTGYTAYAARYTNYTNACNYTN YTNTGYGGNATHCCNATHGCNYTNTGYTGGGGNTGYGARTTYGCNGTNATHACNTTYCAR CAYGTNTGG--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYGTNGTNAARCARGARTGYAGYGCNCARATGGTNGAYMGNGTNGCN AGYGTNGARAARMGNYTNTCNYTNCARYTNGARGARAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYATHAAYAARAARATHCARMGNTTYATHAAYAARMGNAARATH TTYCCNGAYTTYAAYGAYATHAARAGYATHGTNMGNATHGCNAAYAARAARTGYAARYTN AAYYTNAGYGCNYTNAARYTNAAYGAYGTNGCNMGNGARGCNTTYGTNGAYATHGGNGAR ATGYTNCARMGNMGNMGNCAYGARGAYTTYATHGCNACNTTYGGNAAYMGNCARACNGAY GTNGGNATGGAYCCNGCNYTNACNGAYGTNGARYTNMGNMGNAARYTNGARMGNAAYMGN CAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARGARAARAARGARAGYAGYAGYGARGARGAYAGYGAY---------GAYGAYGAYGAY GARGARAARGARAARAARCCNMGNAARGCNCCNAAYGARYTNYTNATGGARTTYGTNGAY TGYYTNATHCAYAARGAYTTYAARAAYGCNGARAARYTNTGYAARATGATHYTNYTNTAY GARCCNGAYAAYGCNGARGCNYTNAARTTYCARCCNYTNATHCARGARAARYTNGARYTN GGNGCN------------------------------------------------------ ------------------------------------------------------------ ------------GAYAARATHATHGARATHGCNTGYGTNGTNACNGARGARGAYYTNACN YTNGTNGARGARGGNCCNAAYYTNGTNATHCAYCARCCNAARGCNYTNATGGAYGGNATG GAYGARTGGTGYACNGARCAYCAYGGNAARTCNGGNYTNACNGCNGCNGTNYTNGCNAGY CCNYTNAGYGTNGCNGARGCNGARTCNCARGTNYTNCARTTYYTNGCNMGNCAYACNGAR CCNGGNGTNTCNCCNYTNGCNGGNAAYTCNGTNGGNACNGAYAARACNTTYYTNGCNMGN TAYATGCCNCARYTNGCNAGYCAYYTNCAYTAYMGNATHATHGAYGTNAGYACNGTNAAR GARYTNTGYMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNGARMGNGARGAYACN TAYGCNGCNAAYMGNTTYGAYTGYCAYTTYGGNACNACNTAYAARGTNYTNGTNGTNCCN AAYGARGCNTCNACNTTYYTNTCNTGYGGNGARGAYGGNACNGTNMGNTTYTAYGAYYTN MGNGTNAARACNACNTGYCCNAARTTYAAYTGYAAYGAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TTYAAYTCNGCNTTYGGNTCNTTYATGGGNATHTTY GTNACNCCNGTNYTNATHYTNTAYATGYTNGGNTCNGARGTNACNGTNCCNACNAGYGCN ATHTTYAGYCARYTNTTYACNACNGTNGTNYTNCCNYTNGTNGTNGGNCAYGTNGTNMGN MGNTGYGCNCARCCNTGGYTNGAYMGNCARMGNATHCCNTTY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGTGGAARAARGARAAYYTNMGNAARAAYTTYYTNMGNGTN AARCARATHGCNGAYCARAAYYTNGGNMGNGCNGARAARTCNGARGTNYTNTCNGARGAY YTNCARGARAAYGARAARMGNGTNGAYGTNGTNAARCAYGTNTAYCARAAYATHACNAAR AARGCNGTNGCNTGYATGCARGCNCCNGGNACNGAYATGGARAARMGNYTNAARAARYTN CCNGARACNGGNYTNGGNCAYTCNYTNGTNGARTCNGCNTCNYTNYTNGGNCARGAYACN YTNYTNGGNTCNGTNTGYCARATHTGYGGNGAYTGYCARGCNGTNYTNGCNMGNGARCAR YTNCARTAYGARATHACNYTNGARAARGARTTYYTNGCNCCNYTNCARAAYGTNGTNGAY ATGGAYATHCCNAGYATHATGAARTAYMGNAARGCNYTNAGYAARTCNACNYTNGAYATG GAYTCNGCNAARAAYMGNTTYAAYCARGCNGTNMGNCARTCNAGYGTNCCNGGNACNAAY ATHGCNTCNGCNGCNGCNAARGCNGAYACNATHMGNGARGARTAYGARGARGCNTCNAAY AARGTNGAYAAYGTNMGNGAYAAYYTNTCNATHGARYTNTGYAAYTTYGCNTCNAARGAR AGYGARCAYAGYCARMGNTTYYTNACNYTNYTNGARGCNCARCARAAYGCNCCN------ GGNCARGAYMGNMGNMGNGAYAARGAYCAYCCNCCNACNAARGTNGTNATHMGNMGNYTN CCNCCNTCNYTNGTNCCNGARGTNTTYYTNGARCARGTNGCNCCNYTNCCNGAYCAYGAY TAYTTYTGYTTYGTNMGNGCNGAYATGAGYYTNGGNAAYAAYGCNTTYTCNMGNGCNTAY ATHAAYTTYATHAAYTCNGARGAYGTNTTYATHTTYMGNGAYAARTTYGAYGGNTAYGTN TTYYTNGAYGCNAARGGNGGNGARTAYACNGCNTGYGTNGARTTYGCNCCNTTYCARAAR GTNCCNAARAARMGNTCNMGNAARCCNGAYGCNAARAAYGGNACNATHGARCARGAYYTN GAYTAYMGNAARTTYYTNGAYGCNYTNGARCAYCCNAARGARGARGCNGCNGTNTCNATH GAYGCNYTNGTNGARGARATHGARAGYAARGARAARGARAAYMGNGCNAGYGGN------ AARYTNACNACNCCNYTNYTNGARTAYATGYTNMGNGAYMGNGAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AARTCNAARAAR YTNMGNMGNMGNTCNATGCCNYTNMGNAAYTTYACNAARCAYTCNAAYGTNGAYMGNGTN GTNGARGARYTNAARAGYAAYGCNMGNCAYGCNMGNTTYATHAARATHYTNTCNYTNGCN CARYTNCARMGNYTNYTNACNATHGTNAARGAYAARATGAAYGGNATGAGYYTNGARGCN AGYYTNGCNMGNAAYGAYGCNATGGAYACNATHAAYCCNGARGARGAYYTNAAYAARGTN GAYGARGARACNYTNCARMGNAARAARYTNCARATGGAYAAYATGTTYGARAARAAYMGN MGNAARCCNGGNGAYCCNGAYTTYGARTAYAAYGTNGARGTNGAYTTYGARACNGCNAAR ATHGARACNTCNGGNTGGGAYTCNGAYGGNTCNGAYCCNGAYTTY >lancei YTNYTNATHGCNCCNYTNYTNYTNGGNGTNGTNATGGCNGGNTAYGAYCCNTAYTCNAAY YTNGCNCARYTNTAYMGNATGCARYTNYTNGCNGARGCNTAYGGNGAYTAYAAYCCNGAR ACNYTNGGNYTNGAYCARAAYGAYGTNGAY------YTNMGNTCNTAYTGGCCNGAYTTY TCNAAYTCNYTNAAYGARGARGARGCNGARGAYAARTCNCCNAGYGAYGCNATGTAYGGN TCNCCNATHTAYACNGGNGCNCARATHMGNGAYCCNGARCAYATHGARCAYAGYTCNYTN CAYGGNTTYCARTCNGTNTCNGGNGGNAAYCCNGARGGNCCNAGYAAYACNAARCARCAR AARTCNGAYAARCCNYTNCCNGCNTAYTGYAAYCCNCCNAAYCCNTGYCCNATHGGNAAR ACNGCNAARGAYAAYTGYGTNGARAAYTTYGARAAYTCNGCNGARAAYAAYAARAAYYTN YTNAGYGARCARGAYTGYCCNTGYGAYACNGARCAYATGTTYAGYTGYCCNGCNGGNCAR GARACNGTNTCNTCNAARGGNCARGCNGGNTAYCARCARACNYTNAAYAARGTNATHGAY CARYTNGCNCAYATGGGNCCNGARGGNCARGAR---AARGGNGAYAGYGTNYTNAAYCCN GCNMGNAARMGNATHACNYTNGTNGCNAARAARTCNCCNCAYATHATHCAYAARMGNTCN GARAARGCNGAR------AAYCCNTAYYTNGGNGGNAAYCAYATGCCNATHGCNGCNAAR AARAAYCAYGARTCNGCNCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNTTYYTNCARATHYTNTCNGCNGCNAGYGTNGARGAY AARTAYGARCCNATGGTNGCNTTYATHTGYGAYMGNCCNGCNATGTAYMGNGGNGTNAAY AGYTGGATHGCNGAYAARACNCARAAYTGYCCNGAYTCNYTNACNGARGTNYTNTCNTAY TGYAARAARGTNTAYCCNAAYCAYAAYATHACNAAYGTNGTNGARTCNTCNCAYYTNTAY GAYATHCCNAAYTGGCCNATGGGNAGYACNGGNMGNCARCAYACNCAYCAYGTNMGNCCN TTYMGNTGYYTNGTNGGNGGNTTYCARTCNGAYGCNYTNYTNGTNCCNCARCAYTGYGTN TTYGAYCAYMGNCAYGAYGTNAGYCARTGYGARGARTTYGCNCAYTGGAAYAGYGTNGCN GARCARGARTGYMGNGCNAARGAYATGMGNYTNGARTCNTTYGGNATGYTNYTNTAYTGY MGNGCNYTNGGNCAYTTYAGYGGNGTNGARTAYGTNTGYTGYCCNGTNGAYACNGCNGAY TCNGGNCAYCCNGARCCN---CARCCNGGNGAYGAYMGNCCNGAY--------------- ------------------------GARATHMGNGARGGNGGNGARGCNGTNCCN------ ------------------------------------------------------------ ------------------------------------------GAYYTNGARGARGCNTAY YTNMGNGGNYTNCCNTTYCCNAARCARTAYGAYAAYGARCAYAARMGNTAYYTNGCNGCN AARGARMGNATGAARCARAAYGARAARATHMGNTAYTCNAARATHYTNGARGAYTGGGAR GCNGCNMGNGARAAYGTNAAYAARYTNMGNAARACNGAYCCNAARGCNGCNGAYAARCAR AAYCARGARATHACNGARMGNTAYAARAARYTNTAYGCNTCNTAYAARAARGARAGYMGN GARGARGCNGAYYTNYTNATGGCNYTNCAYCARCARCAYATHCARGCNTCNYTNAAYCAR CAYGARMGNGAYTCNATGCARAARTAYATGAAYGCNYTNGARGARGGNAAYGTNGAYCAY ACNACNMGNTAYYTNMGNAAYTAYATHAARGCNGARGARAARGAYMGNATGMGNACNGTN AAYTAYTTYGARCAYYTNMGNTAYTCNAAYCCNGARGARGCNYTNMGNACNCAYCARCAY GTNATHGAYCAYYTNAARGCNTCNGARGCNMGNATHGARCARGCNYTNGCNATGYTNACN MGNATGCCNGAYATGGARMGNCARATHMGNCCNGGNATHGARGAYGAYYTNAARGGNTTY GAYGCNATHGCNACNMGNATHAARAAYGTNGTNYTNCCNGTNCCNAARGTNGARGARGAR GCNGGNACNAGYGAYAGYAGYGAYGARGAYGTNTCNGTNGAYACNGAYGAYCAYACNCAR GAYGTNGAYTCNTCNAGYGAYGARCARCCNAGYMGNGTNGARCARCCNTAYCCNCARCCN ATHATH---------------------------------------GAY------------ ---------------------------GAYGARGTNCARGARACNGARCAYMGNTAYGAR CAYCAYCAYTCNTTYTCNGCNAAYGCNATGAAYGAYCARCAYAAYGCNMGNCARGGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARGAYAARYTNTAYMGNCARATHACNGTNGARGTNAARGGNCAYGAYYTNGCNGTN YTNAAYAGYTAYCARAARTTYACNGCNATGGCNGCNGAYGARYTNGGNGTNAAYYTNGAR AGYATHTCNGCNCCNCCNAARGTNATHACNMGNMGNAGYYTNYTNAARTCNGTNTTYATH TTYAARAARCAYCARCAYCARTAYGARACNMGNACNCAYTTYMGNGTNTTYGARTTYAAR CAYYTNACNGARTCNACNGCNYTNACNTTYYTNGARTAYATHCARMGNAAYYTNCCNGAR GGNATHGCNATGAARGTNACNAARCAYGARYTNCARCCNYTNCCNGARCAYYTNAARCCN CCNTCNAGYAGYCARGCNTCNGTNGCNGARCCNACNGAYTAYTTYAAYGTNATGYTNGGN TCNCARYTNYTNTAYAARTTYGARMGNCCNCARTAYGGNGARATHYTNGCNGARAAYCCN GAYAARACNATGTCNAGYATHTAYGGNGCNACNCAYYTNYTNMGNYTNTTYGTNAARYTN GGNGCNATGYTNGCNTTYACNTCNYTNGAYGARMGNACNGTNCAYATHYTNYTNAAYCAY GTNCARGAYTTYYTNAARTAYATGTCNAARAAYGGNGCNAGYYTNTTYAARACNTCNAAY TAYGARATHGCNCCNCCNGAYTAYCAYMGNAARGCNATH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTNMGNMGNAARACNYTNTTY TAYYTNTTYAAYATHATHTTYCCNTGYYTNTGGYTNACNATHYTNAGYYTNYTNGGNTTY TGGYTNCCNCCNGAYTCNGGNGARAARATHACNYTNGGNATHACNGTNYTNYTNGCNTTY TCNGTNTTYATGYTNYTNATHGCNGARAGYATGCCNGCNACNTCNGARTTYGTNCCNYTN ATHGGNATHTAYYTNACNGTNACNATGGGNATGATGTCNYTNTCNATHATHYTNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CARMGNTGGATHCCNYTNGAR TCNAAYCCNGTNGTNGTNAAYAARTAYGTNCAYTGYYTNGGNATGGAYAARGARTGGAAY TTYGTNGAYGTNTAYGGNYTNGAYCCNGARYTNYTNGCNATGGTNCCNAARCCNGTNGCN GCNATHGTNYTNYTNTTYCCNAGYTCNAARTCN------------GARACNCCNATHGGN GARATHATGAARGARTCNCCNTCNGGNYTNTAYTAYATGAARCARACNATHGGNAAYGCN TGYGGNACNGTNGCNATHGTNCAYGCNYTNGCNAAYAAYCARGAYAARATHACNTTYGAY GAYCARAARCAYTTYYTNGARTTYYTNAARGCNAGYTCNTCNYTNACNCCNGAYGARAAR GCNAGYCAYYTNGARAARGAYYTNGAYATGGGNGCNGCNCAYGARGAYTGYGCNCARGAR GGNGAYACNGARGCNCCNGCNGCNAGYGARAARGTNCARTGYCAYTTYGTNGCNTTYGTN CAYTTYAAYGGNACNYTNATHGARYTNGAYGGNMGNAARGAYGGNCCNGTNAGYCAYGGN GCNACNACNGCNGAYAGYATHYTNGARGAYGCNGCNAARGTNGTNAARAARTTYATGGAY MGNACNCCNTAYATGGARGCNMGNGAYACNYTNYTNAARGARGAYCARAARAARAAYYTN GGNCARTCNYTNACNATGTCNAGYCARGARGARAARGTNTCNAAYTTYYTNGTNAARAGY AARMGNCARYTNATHGARGAYAGYMGNATHGGNMGNGARGAYTAYTAYCCNTCNYTNAGY TTYTAYGARTCNAARCCNYTNATHGAYAAYTCNGAYATHTTYCARGTNATHMGNAARATG CCNAARGGNGCNGCNYTNCAYYTNCAYGAYATGTCNATHACNAGYYTNGAYTGGATHGTN TCNAAYGTNACNTAYMGNAAYGAYYTNTTYATGTGYGTNGAYMGNGCNACNTCNYTNATG ATHMGNTTYTTYMGNATGCCNCCNGARAAYCCNGAYTGYCCNTGGATHTCNGTNAARAAR GCNMGNGCNAAYTCNYTNAGYGCNGARCARTTYGAYATHAGYATHAARMGNAAYYTNAGY YTNYTNGCNACNGAYCCNYTNGTNACNTAYCCNTCNYTNACNAARGTNTGGACNMGNTTY GAYAAYTTYTTYTCNCARGTNATHGGNATHATHTTYTAYMGNCCNGTNYTNGGNGAYTAY TTYMGNCARAGYYTNGTNGARTTYTAYAAYGAYAAYGTNCARTAYATHGARYTNMGNTGY YTNYTNTCNGGNGTNTAYGAYYTNAAYGGNAARGAYTAYAGYCAYGARGARGTNYTNCAR YTNYTNTCNGAYGTNGCNACNCARTTYGCNAARGARAARCCNAAYTTYYTNGGNGCNAAR TTYYTNTTYACNTCNYTNMGNAAYYTNCCNAARCARGAYATHGGNAAYATGGTNAARYTN TCNATHAAYYTNATHCARAARTTYCCNGGNACNATGYTNGGNTAYGAYYTNGTNGGNCAR GARGAYCCNTAYAAYCCNYTNYTNTAYTAYAARGAYCARYTNYTNTCNCCNCARCARATG AAYCCNCCNGTNAARYTNCCNTAYTTYTTYCAYGCNGCNGARACNAAYTGGCARGGNACN GCNACNGAYTAYAAYYTNATHGAYGCNATHYTNYTNAAYACNACNMGNATHGGNCAYGGN TAYGGNYTNATHAARCAYCCNAARYTNGTNGAYYTNGTNMGNAARAARGGNATHGCNGTN GARGTNAAYCCNATHTCNAAYCARATHYTNGGNYTNGTNAARGAYYTNMGNAAYCAYGCN ATGATHCCNYTNATGCARGAYGAYTTYCCNGTNGTNATHAGYTCNGAYGAYCCNACNACN TGGGAYGCNACNCCNYTNTCNCAYGAYTTYTTYATGGCNTTYATGAAYATGTGYGGNGAR GAYGCNGAYYTNMGNTTYYTNAARCARYTNGCNATHAAYTCNATHAARTAYAGYGCNATG AGYCCNGCNGARAARGAYCARGCNATGGTNMGNTGGMGNACNCARTGGGAYATGTTYATH ACNAAYACNGTNAARTCNGCNTCNTCNAGYTCNCARCARACNGAYGTNMGNTCNCCNTCN MGNGTNAARMGNGARAGYTGGGAYATGATGMGNTAYTCNMGNGGNYTNCARMGNYTNMGN YTNGGNAARMGNTCNATHCCNTAYATHGAYGAYGAYACNGAYAAYTTYCCNATHAARCCN CCNGARGARCAR------TTYGTNGAYCCNMGNGAYTAYACNTTYGAYTTYCCNYTNCCN TAYTAYATHTCNCCNTAYGAYTCNTAYGARGARATHCCNCAYATGMGNGTNMGNMGNTCN ACNCCNTCNGARCCNCCNGTNGTNACNCCNTAYCCNGCNGTNTTYGGNGARAAYTCNGCN GARGAYATHTCNGAYGARYTNAARGAYGCNGAYAGYGAYGAYCAYTAYYTNYTNTAYCCN GTNTCNTAY------------AAYGAYGAYGCNAAYGAYTGGAGYGAYGAYGTNAAYMGN ATGGAYAARMGNCARYTNCCNATGTTYMGNYTNGGNAARMGNAAYYTNAAYATGYTNMGN YTNGGNAARMGNAARGAYGARAAYATGAAYAGYGCNTAYACNMGNGGNGAYGARATGGGN ACNCCNTCNATGATHGCN------GCNAARMGNAAYYTNAAYATGYTNMGNYTNGGNAAR MGN------AAYTCNYTNCARGARATHAARMGNAAYYTNAAYATGYTNMGNYTNGGNAAR MGNGAYCCNGCNGARATH---------AARMGNAAYYTNAAYATGYTNMGNYTNGGNAAR MGN------GARAAYTTYGGNCARGARAARMGNAAYYTNAAYATGYTNMGNYTNGGNAAR MGN------GARTCNTTYGARAAYGARAARMGNAAYYTNAAYATGYTNMGNYTNGGNAAR MGN---------GARTCNYTNGARAAYAARMGNAAYYTNAAYATGYTNMGNYTNGGNAAR MGNGTNTCNYTNGARCARGARAARMGNAAYYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGARCAYTTYAGYATHGTNYTNGTNGTNYTNGTNGCNTCNATHGTNTGYGCNCARATG GCNACNGCNTCNCCNACNMGNACNGCNCARGAYATHYTNCARGAYACNTCNAGYYTNATG ATGGAYAARMGNCCNAARTAYATGGAYACNMGNMGNGAYYTNGAYGTNYTNAARGAYYTN GTNYTNATGAGYATHCARGARYTNGTNGAYGARGGNMGNYTNGAYACNTCNGTNYTNCCN GARGAR------GAYAARAGYTCNGCNAARTCNGTNGARAARMGNMGNTAYATGGGNYTN TGYATGCAYMGNCARGCNAAYCARTTYATHCCNTTYCCNTGYYTNMGNGCNGGNMGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHYTNACNYTNAGYTTYTTYGCNGGNAGYGCNTGYGCNGTN TTYTAYYTNCCNGGNTCNGTNGTNAGYTAYCCNAARATGGGNAARMGNGCNTTYTAYACN AAYGCNACNGGNAAYMGNTAYCCNYTNATGGGNMGNMGNTCNTCNCCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AAYGGNGARTAYTTYTAYAARYTNTCNTCNMGNMGNATGMGNTCNAARGARGTNCAR GTNATHCCNTGGGTNGTNTCNGAYAGYAARTAYTCNTTYCARCCNGCNCARMGNYTNGAY MGNAAYMGNACNGTNTTYGTNGGNGCNYTNCAYGGNATGYTNACNGCNGARGCNYTNGGN ATHATHATGGCNGAYYTNTTYGGNACNGTNGTNGARGCNGGNATHGAYACNGAYAARCAY MGNTAYCCNATHGGNTCNGGNMGNGTNACNTTYYTNAAYMGNAARAGYTAYATGAARGCN ATHCARGCNGCNTTYATHGARATHAARACNCCNAARTTYACNAARAARYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGYGAY--- CAYAAYCCNCAYCCNTAYCCNMGNGGNYTNTGYGGNCAYCARYTNATHAGYATHTTYGAY MGNTTYTGYACNACNYTNCAYACNAAYMGNMGNACNYTNGTNAARMGNTCNGTNGARGCN GCNAARACNAAYTCNYTNAAYMGN---YTNYTNGGNATHYTNMGNAAYCCNMGNGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYGCNATHTTYGCNAAR MGNGGNGCNCCNMGNTTYGTNGGNAARMGNCARGCNCCNMGNTTYGTNGGNAARMGNCAR GCNCCNMGNTTYGTNGGNAARMGNGGNGCNCCNMGNTTYGTNGGNAARMGNCARGCNCCN MGNTTYGTNGGNAARMGNGARAGYGAYATGGCNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNYTNCCNAARACNATHTAYCCNYTN CAYTAYGAYYTNYTNYTNAAYGCNGAYGCNGAYTGYGGNAAYTTYACNGGNGARYTNAAR ATGAAYGTNATHGTNAARGARACNACNAAYCARATHGTNTTYCAYTCNAARGAYYTNACN ATHAAYAAR------------GTNCARTGYMGNTAYGGN------------ATHAARAAY CAYTTYGTNGGNAARGGNGARCARTAYTAYATHATHATGAAYGAYMGN---YTNGARAAR GGNACNGARTTYGAYGTNAGYATH---TTYAGYGGNAARGTNAAYTCNGARAARMGNGGN TTYTAYAARCAYTCN------ATHAARAARAGYAGYMGNACNGTNTGGAGYGCNTTYYTN GARCCNAAYTAYGCNMGNACNGTNTTYCCNTGYTTYGAYGARCCNGARTTYAARGCNACN TTYGCNYTNTCNATHGTNMGNCCNCARGAYYTNATHACNYTNTTYAAYACNCCNYTNYTN GGNACNTCNGAYTAYAARGAYTCNAARTCNAARAGYAARTAYAARAARACNCCNGARATG AGYACNTAYNNNYTNTCNTTYGTNATHNNNNNNTTYNNNTCNNNNNNNAARNNNNNNAAR AAYNNNCCNAARGARAARNNNGAYYTNCARATHGGNNNNNNNGGNATGNNNNNNNNNACN YTNNNNNNNGCNNNNAARYTNNNNNNNCAYNNNNNNNNNYTNTTYNNNGTNNNNYTNCCN YTNGARAARYTNGAYNNNGTNNNNNNNNNNYTNNNNNNNNNNNNNNNNTTYGARGGNTGG GGNYTNATHACNATGNNNGARNNNTAYNNNNNNNNNGAYNNNNNNNNNNNNNNNNNNNNN NNNAARNNNNNNGTNNNNNNNYTNYTNNNNCAYGANATHNNNNNNNNNTGGTTYGGNAAY NNNGTNACNNNNAARTGGTGGNNNGAYNNNTGGATNCARNNNGGNNNNNNNGANTTYYTN GCNNNNACNNNNNNNNNNGANATHNNNNNNNNNNNNNNNNNNNNNNNNATNMGNYTNGTN MGNYTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGNNNN NNNATHNNNNNNNNNNNNGAYATGNNNNNNNNNTAYACNAARNNNNNNNNNNNNAARGGN GCNNNNNNNTTYMGNATGYTNCARNNNGTNATHGGNNNNNNNAARYTNNNNGARGGNYTN NNNNNNTAYATHNNNNNNTAYAARYTNNNNAAYGCNNNNTCNACNGAYYTNTGGNNNNNN YTNCARTCNAAYNNNGAYNNNNNNNNNAANGTNNNNNNNNNNATGNNNTCNTGGACNACN CARCCNGGNTTYCCNGTNATHACNGTNACNMGNCARAARAAYACNTTYACNTTYCARCAR AARCCNTTYACNGTNGAY------------------------GGNAAYAGYAARTCNAGY CAYACNTGGMGNTTYCCNTTYCARTAYMGNACNTCNAGYAARAGYAARGARGTNGGNAAR ATHYTNATHCARGARAARAGYGTNACNATHGAYGGNAAYCCNCCNYTN---TGGATHATH GGNAAYAAYGAYGGNAGYGGNTAYTAYMGNGTNAAYTAYGAYCCNGAYACNTGGGAYGCN ATHGARAARCARYTNYTNGAYGAYCAYACNGTNTTYTCNACNGCNGARMGNYTNTGYYTN ATHGAYGAYGCNTTYGCNYTNGCNGARGCNGGNGARYTNTGYTAYTCNCARGCNTTYAAR YTNYTNAARTAYYTNGCNAARGARGARGAYTTYGAYGTNTGG------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CCNAARGAYATGGGNYTNAAYGAYGAR GARTCNTCNGARACNGARTCNAARGCNGARGCNTTYAAYAARAARATGAGYGGNGGNAAR YTNGTNTAYGAYMGNGCNTAYYTNATGGARYTNMGNGARTGYGCNTCNTCNCARACNAAR CCNGAYGGNYTNCCNAARYTNGAYATHATHYTNGAYAARCCNAAYATHAGYYTNYTNTCN MGNCCNTCNGGNGGNCCNGCNGAYTTYACNCCNTCNTTYTTYCARCCN---------ACN CARMGNCAYGCNCCNCCNATHGGNAARAGYAGYAGYMGNGGNMGNCARMGNCCNGGNGAY ATGCCNACNACNCCNMGNGTNATHAARAGYATHTCNATGTCNAAYGAYACNAARGCNYTN CAYCARAGYGARAAYCCNTGGAAR---------CCNGTNAARAARGARGAYAARGAYGAR CARAARGGNYTNGARGGNGARATHYTNTTYATHATGAAYMGNYTNACNCCNACNAAYTTY GARAARATGGCNMGNGARATGMGNAARYTNAAYGTNAARACNTAYGAYGAYYTNAARTTY ATGGTNAARGTNTTYTTYGAYAARGTNACNATHGARACNAARTTYGTNGARGCNTAYGCN CARYTNTGYAARGTNATGGCNGAYYTNAARGTNCCNCCNCCNGCNGAYGGNAGYGTNAAR GAYCAYYTNGCNACNTTYMGNGTNGTNATGYTNACNAARTGYCARCARGARTTYGARGCN GAYAARGCNATHATHTTYGARAAYCCNGARGARAARAARAARAARYTNGARGCNGAYAAY CCNGARATHACNCCNGARMGNAAYGARATGATHGARAAYACNYTNTAYCARATGAARYTN AARMGNATGAARTTYTAYGGNAAYATHMGNTTYATHGGNGARYTNTTYAARYTNMGNYTN YTNACNGARAAYATHATGCAYGAYTGYATHTAYMGNYTNYTNAARGCNMGNGAYGAYGAY TCNYTNGTNTCNYTNAGYAAYYTNYTNACNACNGTNGGNMGNYTNYTNGAYACNGAYAAR GCNAARCCNMGNATGGAYCARTAYTTYTCNCARATGTCNAARATHGCNGAYGARMGNAAR TCNMGNATHAARTTYACNYTNAARGAYGTNATHGARYTNMGNGGNAAYCAYTGGGTNCCN MGNAARGARACNACNGGNCCNAARAARATHGAYGARGTNCAYAARGAYTTYGCNCARGAR CARGCNMGNAAYCARTTYYTNGCNTCNCARCCNGCNCCNCCNMGNATGGAYAAYTCNCAR GTNGGNAGYMGNMGNGGNAGYMGNCARMGNCARGARGAY---AARACNAAYGARGAYGGN TGGAAYACNGTNTCNTCN---AAR---GTNAAR---ATHGARCCNACNAARATGAARTTY TCNAARAAYGCNTAYGCNGAYGAYAAYATHCARYTNGGNCCNGGNGGNGGNATGYTNMGN CARCCNATGTGGAGYMGNGGNAGYCAYGGNGGNGGNTCNCARCCNTCNCARGARGAYMGN TCNTCNGGNGGNTCNAAYMGNTTYGCNGCNYTNAAYGAYGAY---TCNAARMGNTCNTTY CCNMGNTCNCCNTCNMGNGGN---GARAAYACNCCNMGNGGNGTNMGNCARGGNCCNACN GCNGGNCAYGGNMGNGGNAARATGATGTCNMGNTCNAGYCARGARGGNGAYMGNMGNGAY ---YTNCCNTCNTCNMGNTCNTAYATGGGNGGNATGTCNCARAGYTCNAGYMGNGAYAAY AGYTGGAAYMGNAAYGAY---MGNMGNCARATGGGNCCNMGNAGYTCNGGNGARMGNGAY GAYYTNATGACNMGNAGYGGNAGYTCNAGYMGN---MGNGAYGAYTTYGCNGTNCCNGCN CCNGTNCCNTCN---GTNAARCARATGAGYGARTCNGARATHGARAARAARGCNGCNAAY YTNYTNGARGARTAYYTNAAYATHMGNGAYATGAAYGARGCNAARYTNTGYGTNGARGAR YTNAARGGNCARAARTCNATHCAYTGYGTNGTNTCNGCNTTYATHAAYAAYGTNYTNGAR AARAARGAYGARGCNMGNMGNYTNACNGGNAAYYTNYTNCARGARYTNGTNYTNGCNGGN AARATHTCNCCNAGYATGTAYATHAARGGNYTNAAYGARGTNYTNGARTTYGCNAGYGAY ATGGTNGTNGAYATHCCNACNYTNTGGAAYTGYYTNGCNCARGTNATHTGYCCNYTNYTN ATHGGNGGNTCNYTNCCNTGGTCNGARYTNAARCAYGCNYTNACNCCNCAYYTNGAYAAY AARGAYGGNGCNAARYTNYTNGCNGCNATHYTNYTNAAYTGYGCNGARAAYCARGGNGAR AARGARGTNGCNCAYCARTGGCARAAYAGYGGNYTNGTNTGGTCNAAYTAYYTNAARCCN GAYGARATHGGNACNTTYATHTCNGAYAARAARYTNTCNTTY------------------ ---------------ACNYTNGGNGARTCNACNGGNGARGAYGTNAAYMGNTTY---AAR GARATHGARMGNATGGTNCARAAYMGNGCNACNAAYAARGARYTNATHTCNCAYATHGAR ACNAAYATHTCNGGNAGYAARACNGAYAAYAAYTTYATHMGNTCNYTNACNACNGCNYTN GTNMGNGCNTCNATHTCN---------GARTCNAAYAARYTNAAYGARGARGTNYTNAAR AGYCAYAARGARGTNYTNCARAARTAYYTN---GGNAGYGAYATHGAYMGNCARYTNCAR GCNYTNTAYGCNATHCARACNYTNATGGCNAARYTNGARCAYCCNTCNGGNATHYTNATH AARYTNTTYGARYTNTTYTTYGAYGARTTYTCNATHGARGARGARGTNTTYTAYMGNTGG GARAARTCNGAYGAYCCNCARGARCARGARTCNAARGGNACNTGYGTNATGCARGTNMGN CARTTYTTYATHTGGYTNMGNGARAGYGARGAYGTNGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYCCNYTNGGNGAYGAYACNATGGARACNTTYATGAAYYTN GAYCARTTYYTNGAYGARAAYTCNYTNTTYGAYGARTAYGGNGAYAAYTCNATHGTN--- CCNAAYGTNGARGCNGARGTNGCNCCNGTNATHAAYTTYGAYYTNAAYCCNCARGARYTN AGYTCNATHCCNAGYYTNGARGTNGARCCNGCNAGYACNGAYGCNGCNYTNYTNGCNGGN AARACNAGYAARAARMGNMGNCCNGAYCCNTCNTCNGGNGGNGTNAARACNAGYYTNTTY GARATHCCNGARACN---------------GTNTCN---------------------GTN ATGGCNGCNGAYAGYGARYTNGAYCAYGAYTAYAGYACNAARMGNCARMGNGTNTCNGTN TCNTCNGGNGAYGTNTCNAARAARGARCCNGTNGARGCNCARAAYGCNAARGCNAARTCN CARCARAAYACNAGYAARGCNTCN---------------TGYACNGCNGARGGNGTNAAY AAYGAR------------------AARGTNGAYAARCARGCNATHMGNMGNCARAARAAY AAYGTNGCNTCNAARMGNTCNMGNGARCARMGNAARAARAARTTYGTNGARTTYGARCAR GARGCNGAYGARYTNGTNGTNMGNAAYCARCARYTNMGNGARAARATHGTNGARYTNGAR MGNYTNGCNAARGARATGAARGCNGTNYTNGTNGCNAARATGACNGGNAARGCNMGNTCN AAYGGNACNACNCCNYTNAAYGCNTTYYTNCCNMGNTTYATHAARAAYCAYGAYTGYYTN YTNTGYCCNAGYAAYYTNGAYATHAARATGCCNAAYGAYACNGGNCAYACNYTNGTNGTN GAYTTYYTNGCNCCNCCNACNCARTTYGGNTTYTAYCCNYTNGCNGCNGAYTTYGTNGAY GARTTYAARTCNGARAARGTNMGNCCNCAYTGGGCNAARMGNCAYGAYAAYATHGARGGN ATHGTNGGNMGNATHAARTCNGTNTTYGGNGAYAAYYTNGCNGARTTYCARMGNCARMGN MGNYTNGCNAARGTNGAYCCNTGYGAYATGTTYACNAAYAGYTAYYTNYTNTCNGTNTTY GGNGARAGY--------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------------TCNGAYATH ACNGARACNGGNTGYYTNTCNCARCCNCCNAARGTNCARGGNGCNACNGCNAGYCCNTTY ACNAAYACNTTYTAYGGNAAYGCNCAYAAYGCNGGNATGTAYTCNAAYCCNTTYATHCCN MGNGCNCCNTTYAARTCNGAYGTNGTNTCNTCNGAYCARTCN---------------AGY TCNGGNYTNATHGCNCCNAGYMGNYTNGGNGCNTCNGTNAAYAGYTCNAGYTCNGARGCN GARAGYGAYCCNMGNMGNGGNTTYYTNAARTCNTCNGTNYTNGCNCCNCCNMGNYTNACN GGNGCNGCNTTYGGNGGNGCNAGY---AAYCAYGAYACNCCNAGYTCNACNTTYAAYTCN TTYAAYGCNTTYAGYYTNMGNCCNTCNGTNTTYTCNGGNCCNTTYGAYTCNGGNAGYGAY MGNGGNTCNTCN---YTNYTNAARCCNGCNMGNYTNCCNGAYCCNACNAARYTNAAYGAY GAYAARGTNGAYTCNGCNAGYGARGCNGAY------GTN------CCNTCNTCNAARTCN GCNGARGTNGCNTTYCCNAGYGAYMGNYTNAGYGGNGCNGAYGCNCCNTCNGGNGGNAAY GARGTNTCNTCNTCNTCNTCNACNCCNTCNTCN---------GTNCCNGCNGCNAARGCN TCNTCNGAYGAYGCNGCNAGYAGYGARAAYACNCCNTAYAAYCARGAYATHGTNCCNGAY ATHAAYAARAAYAAYMGNYTNAARGAYTCNTCNGGNGTNTCNAGYAGYTCNCARTCNTTY GTNTTYGGNAGYAAYATHTCNCARMGNGTNACNGGNGTNGTNTCNCCNGCN---GTNGAY AAYGARGCNACNGCNGCNTCNGGNTTYGTNTTYGGNGARTCNYTNGGNGCNMGNGCNAAY GTNGARACNAAYGGNTCNGCNCARGCNTCNAARGARGARGARAGYGAYTCNGAYTCNGGN AAYAARYTNAAYCARACNYTNGARGARTCNGCNMGNGARTAYCARGCNAARCAYGGNACN AARACNGARYTNAARGARGTNGARACNATHACNGGNGARGARGARGARTCNAAYGTNYTN CARGCNAAYGCNAARYTNTTYTTYTTYGARACNAGYAAYGARTCNTGGGTNGARMGNGGN MGNGGNATGATHMGNYTNAAYGAYATGTCNGCNMGNGGNAAYATHAAYTTYCARTCNMGN YTNGTNATGMGNACNCARGGNAGYYTNMGNGTNGTNYTNAAYACNAARATHTGGCCNGGN ATGTCNYTNGARMGNGCNTCNCCNAARTCNATHMGNATHACNGCNATGGAYACNGAYAAY TCNATHAARGTNTTYYTNATHGCNACNACNGCNAARGAYTCNGARAAYATHYTNMGNGCN ATHGAYTGGMGNATHCARCARYTNAARATHCARGARGARCCNGTNMGNCARYTNTCNGAY TCNMGNACNGGNGAYAARMGNAARGCNGAYGAYTCNGAYTTYGARCAYCCNGTNAARAGY AARAARGTNAAYAGYTCNYTNGAYCARAGYATH---TCNATHAARAARGARGARTCNGAY AGYAGYGTNCARGAYCCNGARACNGARGCNTCNTGYGARAGYCAYTCNTCNTCNYTNACN ATHAARTCNGARTCNGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGCNTCNTCN AARGTNTCNMGNCCNYTNGTNAARTCNYTNAARGGNMGNCCNTTY---GCNACNGCNGCN GCNCARGCNGAR---AARAARMGNGTNGAYTCNGAYTCNATGTGYTCNATHAARAARYTN AGYAAYGGNATHCARGTNGGNGTNGTNCARTCNAAYTCNCCNATHGCNMGNATHGCNGTN GTNGCNAAYGCNGGNTCNMGNTTYGARAAYGGNGAYAAYCARGGNGTNTCNCAYTTYYTN MGNATGTCNTCNAARYTNMGNACNGARAAYATGTCNAGYYTNGCNYTNACNMGNACNACN CARCARTTYGGNGGNGAYATHTCNATHYTNGGNACNMGNGARTAYATHTAYTTYAARGGN AAYGTNACNMGNAAYTGYACNGARAARATGGTNMGNGTNYTNCARGARATGACNACNAAR CARGTNTAYAARCCNTGGGARGTNACNGAYGTNCARAARGAYCARGAYGGNYTNYTNYTN GAYYTNGCNYTNTAYCARACNAARCCNCAYGTNMGNGCNGTNGARYTNYTNCAYTCNGCN GCNTTYMGNAAYACNYTNGGNAAYTCNYTNTTYGCNCCNGAYCAYTCNGTNGGNAARYTN ACNTCNGAYCARGTNATGCARTTYGTNAARACNTAYTTYAGYGCNGGNMGNATGGCNYTN ATHGGNGTNGGNGTNGAYGCNTTYCARYTNGARGARYTNGCNTCNCARTTYGARCCNTAY GCNTCNGCNGGNGCNCCNGARCARAARTCNTCNTAYCAY---GGNGGNGARATHMGNGAY AAYTCNGGNGGNGAYGTNTCNTAYGTNGCNGTNGGNTTYTCNGGNCCNGGNYTNACNAGY AARGAYATHYTNGCNGCNGARGTNYTNMGNCAYATHATGGGNACNGGNTCNCAYATHAAR TAYAGYAAYGGNACNTCNGTNGCNAGYYTNGCNAARGCNGCNAGYGCNGCNACNGAYGCN CCNTTYCAYGTNTCNTGYYTNAAYGCNACNTAYACNGAYAAYGGNYTNTTYGGNTTYACN GCNGTNGCNCCNTCNTCNCARATHGARAARGTNGTNCARGCNGCNGGNAARCARYTNAAR GGNYTNTCNTCNGGNAGYATHTCNGAYCARGAYGTNACNMGNGGNAARAAYCARYTNAAR GCNGARATHTGYATGCARTTYGARAAYCCNGAYGTNATGYTNAAYTGGYTNGGNGARCAR GCNYTNAGYGGNGARCARGTNATHACNCCNGAYGARATHAAYAARATGGTNGAYGCNATH AGYGCNACNGAYGTNAARAAYGTNGCNAARAAYATHGTNAGYTCNAARCCNTCNATGGCN TCNACNGGNAAYATHAGYAARGTNCCNTAYYTNGAYCARATHATGGGNGGNAARAGYAGY AARCCNAARAAYAARAARGGNAARAARGARGARGAR---GCNAAYGGNGARACNCCNCAR GARCARCCN------CARGCNGARGCNGGN---GCNGARGGNGARCARAARGTNGARGAR AAYGGNAARGCNACNACNGTNGAR------------------------------------ ---------------------------------------GARGGNGARAAYAARGAYGAR GCNAARGAYAARGARCCNGCNGCNGARACNACNGAYGCNGARCCNGCNAARGARGARGGN AARCCNGCNGARGAYGCNAARCCN---AGYGARACNCCNGARACNGCNAARTCNGARGAR CCNGCNAARACNGARGARCCNACNAARACNGARGARCCNGCNAARACNGARGARCCNGCN CCNGCNCCNGTNGARGCNGCN------------------AARGARGARCCN--------- ---------GCNCARGARGARGCNACNAARGARCARGARCCNGARGTNCARCCNCCNCCN CCNGARCCNGCNGCNGARGARGCNGCNGCNACNGARGARGARAARCCNGCNGARGAYAAR CCNGCNGAYGARCARACN---------------CCNCCNCCNGCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYGARAGYTCNCCNGCNAARCCNTCNGARTCNGCN GARACNGGNGCNGCNGARAGYAGY---------GCNGCNGARACNGGNGARACNGCNCCN AGYGARGARAAYTCNGCNCCNTCNACNGTNAARACNGARGTNAARTGGGARAAYGGNGGN GARACNGTNYTNGTNAGYGGNAGYTTYAAYAGYTGGCARGAYAARATHGCNYTNTCNAAR GAYGGNGAYGTNTTYACNGGNGTNYTNGAYYTNCCNGTNGGNGARTAYYTNTGYAARTTY ATHGTNGAYGAYGARTGGGTNATHAAYAARAAYYTNCCNATHAARTCNGGNGARGAYGGN CARGARAAYAAYGTNATHYTNGTN------------------------------------ ---------------TCNYTNTCNACNATHGGNAAYYTNCARYTNTTYGTNTCNAARCAR AAYGTNCAYMGNTGGGAYACNGAYATHTCNGTNATHGGNMGNTTYYTNTGGGAYYTNTGY YTNYTNTGYYTNTTYATHGGNCARCAYTCNYTNATGGCNACNCCNTGGTTYAARMGNCAR YTNCAYTCNTGGYTNMGNATHTCNGTNTCNGARMGNYTNYTNTAYYTNTGYGCNACNTGY GCNTTYYTNYTNACNYTNATHYTNTCNTGGTAYCCNATHCCNAAYGTNTTYYTNTGGTAY ATHGAYACNAGYGAYMGNCCNTTYYTNTGGGCNTTYTTYYTNYTNTGYCAYTTYGTNGGN TGGYTNYTNATHGGNYTNGARTCNATGTGGATGGAYYTNGGNGARYTNTTYGGNATHACN CARGTNTAYAAYTAYCAYAAYGTNYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TGYCCN GARGGNMGNTGYGAYGAYYTNYTNCCNGTNTTYATHTAYTGYGTNGTNATHCCNGTNACN GTNATGACNTTYYTNYTNGTNYTNYTNTCNGTNGTNATGTGYTGYAGY---AARTCNTGY TCNTGYAARAARTAYTCNTCNYTNACNGCNGGNACNAAYGAYATHCARATGGAYAGYTAY AAYACNATHMGNMGNGCNTCNGCNAGYYTNMGNMGNATGTCNCAYCAYMGNGARTCNGCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TGGAARGCNAARGCNATHAARYTNGARAARGTNATHMGNACN YTNTCNAGYCAYTGYGTNAARGTNGTNGAYAARCAYGARGARYTNYTNACNAARTTYCAR AARAAYCARGARCARTAYGARATHATGAARTCNAARTTYCARGARAARGGNGARCARATH AARAARGCNMGNGAYGTNYTNGTNCCNGTNTCNAAYGARYTNACNTCNYTNMGNGARAAR TAYAARATHGCNGTNMGNTGYCARGTNGARGCNGARAARTTYGCNGTNAARACNACNCAY AARAAYAARGARYTNAARMGNCARAGYCARATGYTN---------------GGNACNAAR YTNGGNTCNATGGARATHGAYATHGAYGCNATHGARTCNGARGARGARAARGARTAYATH GARAARYTNGGNMGNCARATHGAYGAYYTNGARGARGARAARAGYGTNYTNACNGCNCAR GTNAARGARATHACNGARAAYTAYGARYTNGARAARGARGCNAAYGGNAARYTNMGNGAR AARATHGARCARATGAARGARGARGTNAARAARGCNACNGCNACNATHAARCARCARGAR GARYTNTTYCARCAYGTNGCNTCNACNTCNGARAARGCNTGYAARGARTTYGARGTNATG CARCARACNTAYGCNAARGARAARYTNGTNMGNAGYGARGCNGARMGNGTNGCNCAYMGN YTNTTYAARGARMGNGAYCARGCNMGNMGNGARAGYTCNYTNGCNYTNAGYAARGTNGCN GAYAAYAARAARGTNATGGAYYTNATGYTNGARATHCARGAYYTNAAYAGYCARGCNGTN CARATGAARGARGAYCAYGAYAARAARGTNAGYGARYTNGARGARCARYTNYTNGCNGCN AARGARYTNTGYGAYACNGARAGYYTNGARTCNGARAAYGARGARYTNCARCARGARMGN AAYGCNYTNCARGTNAARYTNGARAARAGYGARGGNGARGTNAARCARYTNAGYAARCAR TAYTCNGAYYTNYTNGARACNTAYAARACNYTNGARACNMGNTAYGARTCNGCN---ACN MGNCCNCCNCCNCCNCCNCCNCCNCCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNAGYCARMGNTCNTCNGCNAARGGNGAYTCNAGYGGNAARATGACNMGN TCNGARMGNCAYATGATGAARYTNAARMGNATHATHGCNACNGTNYTNCARGARAARGGN GTNGARGARGGNGAYCCNATHCAYGCNGCNTGYTCNAARAAYYTNYTNAAYGTNAGYATH ATHYTNYTNAARACNYTNCCNAAYTCNATGAAYYTNACNAAYGARATGAARTCNGTNGTN TAYGARCARGTNCARCARATHATHAAYYTNGARAARMGNMGNTCNGGNATHGCNATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AGYMGNGAYMGNMGNMGN---MGNGARMGNGAYMGNGTNMGNMGNMGNAGYMGNAGY MGNGAYMGNGAY---TCNMGNMGNAARMGNAGYMGNTCNCCNGCNAARMGNMGNAGYMGN AGYCCNGTNMGN---GARMGNYTNCCNGARATGACNGTNGARGARMGNGAYATHMGNACN ATHTTYTGYATGCARYTNTCNGCNMGNATHMGNCCNMGNGAYYTNGARGARTTYTTYTCN TCNGTNGGNAARGTNMGNGAYGTNMGNYTNATHACNGAYAAYAARACNMGNMGNTCNAAR GGNATHGCNTAYGTNGARTTYGCNGAYCCNGARTCNGTNACNYTNGCNATGGGNYTNACN GGNCARMGNYTNYTNGGNGTNCCNATHATGGTNCARCCNTCNCARGCNGARAARAAYMGN GCNCARCCNGCNGCN---ACNCARGCNGCNAARCCN---CCNACNGARGGNCCNYTNMGN YTNTAYGTNGGNTCNYTNCAYTTYAAYATHACNGARGAYATGYTNAARGGNATHTTYGAR CCNTTYGGNAARATHGCNGAYATHAARATHATGMGNGAYCAYGAYACNCARMGNTCNYTN GGNTTYGGNTTYATHAAYTTYGCNAAYGCNGAYGAYGCNAARAARGCNYTNGAYCARYTN AAYGGNTTYGARYTNGCNGGNMGNCCNATGAARGTNGGNCAYGTNACNGARMGNACNGCN GAYGGNACNGCNAAY------GGN------GCNGGNGGNCARCARYTNGAYACNGAYGAR ATGGAYMGNGCNGGNATHGAYYTNGGNGCNACNGGNMGNYTNCARYTNATGGCNAARYTN GCNGARGGNACNGGNTTYCARATHCCNCARTAYGCNGCNAGYGCNYTN------------ ------------AGYATGTCNGGNCARCCNCCNGCNGGNGCNGCNCCNYTNCCNAAYGCN GCNCCNGTNAGYGCNAAYATHCCNGCN------------------CCNACNCCNGCNACN GGNGTN---------ACNCCNCCNATHGCNACNCARTGYTTYATGYTNGCNAAYATGTTY GAYCCNACNGTNGARCCNMGNYTNAAYTGGGAYCARGARGTNMGNGAYGAYGTNATHGAY GARTGYAAYAARCAYGGNGGNGTNYTNCAYATHTAYGTNGAYAARAAYTCNCCNCARGGN AAYGTNTAYGTNAARTGYCCNACNATHACNGCNGCNGTNGCNTCNGTNAAYTCNYTNCAY GGNMGNTAYTTYGGNGGNMGNGTNATHATGGCNAARGCNGCNCARTTYGAYGAYAAYTTY GGNGAYCARAARYTNGAYATGGCNCCNTCNMGNGCNCAYTTYAAYGTNAGYGARGARYTN MGNYTNTCNAGYYTNTCNYTNAGYAARMGNAAYATGGTNATGGAYGARGAYMGNTTYGAR GARCARTTYYTNAARTGYTCNATHTGYAARACNMGNTTYACNCARACNTCNYTNCCNMGN YTNYTNCCNTGYCAYCAYTCNTTYTGYCAYGCNTGYGTNYTNCAYGTNTAYMGNAARGCN AARGARCARMGNCARGCNYTNCARGCNTCNYTNMGNACNATGACNGCNCCNYTNACNACN GTNAAYGTNACNTGYCCNACNTGYMGNTCNAAYTTYCCNGCNACNGARGAYAGYGTNCAY AARYTNCCNACNGAYCAYMGNGTNGTNCARYTNATGGAYTTYATHAAYCAYACNGARMGN TCNACNATHTCNTAYTGYTCNAARCAYGAYMGNYTNCCNYTNAAYTTYTTYTGYGARCCN TGYGTNMGNCCNATHTGYMGNGAYTGYACNYTNAARGAYCAYMGNGARGAYMGNGGNCAY YTNGTNATGGAYYTNGARAARGCNYTNGCNCARTAYATGCCNGCNYTNGAYACNGCNATH ACNGARATGGAYGCNGARGCNAAYAGYATHGARGARAARAARACNGCNYTNGCNTCNGTN GCNCARAGYGTNGAYGAYGTNAARTTYGAYYTNYTNTCNGAYGCNMGNGCNGTNATGAAY MGNYTNMGNAARGTNATHGAYGARMGNGARAARGCNYTNGARGCNAARATHCAYYTNGAR ATHGARAAYGARAARMGNAARYTNGGNGAYAARAARGARCARYTNTCNCARMGNAARAAR ATGYTNGARACNCARACNAARMGNYTNMGNCARGCNAAR---GARGGNAAYGTNGARGAY ATHTTYCAYATHCAYGARGAYATHMGNGARTAYATGGCNGAYCCNCCNATHAARATHMGN GARGTNGAYGAYGGNATHATGACNTCNTTYACNYTNATHGCNMGNGAYGARTCNYTNYTN ACNTCNMGNATHAAYAAYTTYGGNGARGTNTGYACNAARATGGARACNACNGCNTCNAAR ACNAARACNCCNYTNMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARTCNTGGGCNTCNCAYGTNAAYAAYYTNTGGCARTGYGGNCCNACNGAYMGNAAR GARGTNACNGCNTTYAAYMGNAARATGGCNGCNMGNAARCCNCAYTGYTGYATHTGYTCN YTNTTYCAYCARTTYGAYCCNGGNACNGAR---------TGGACNGARYTNGAYAARATG GCNGCNACNGAYGTNMGNCCNTCNMGNTCNCARCCNACNGTNCCNGAYTCNGCNTTYGCN GCNAGYGGNGCN---AARAGYGCNGTNTGYGAYTTYTCNTCNYTNGAYGGNGAYGGNYTN AGYGCNYTNYTNGTNTGYTGYTCNTGYCARATGTGYGTNCAYGCNMGNTGYTAYGGNGAR ATGGARGCNGTNTCNGAYGGNCARTGGACNTGYGARGCNTGYACNTGGMGNGARCARCAR CAYAGYAGYCARTGYCARYTNTGYTAYYTNGGNGGNGGNGCNYTNMGNCCNACNCARGAR GGNGGNTGGGCNCAYATHGTNTGYGCNYTNGTNATGAGYGAYGTNGCNTTYAARAAYGTN YTNACNMGNTCNCCNATHGTNACNGCNMGNATHAAYCCNGARMGNTTYGAYYTNAARTGY TCNYTNTGYGGN---GTNGCNGCNAARGCNCCNMGNCCNMGNCCNTGYGTNCARTGYTCN CAYGGNMGNTGYYTNACNGCNTTYCAYGTNACNTGYGCNTTYYTNGCNGGNYTNMGNTTY GCNCCNAGYGAYTGGCCNGTNCCNATHACNGTNTCNTGYMGNMGNCAYYTNACNCCNMGN YTNYTNGCNGCNAARCARMGNGCNYTNCCNCCNYTNGAYGTNGGNTGYYTNGTNGTNGCN AARCAYMGNAAYACNMGNTGYTAYTGGGCNTGYGTNTCNGAYGTNCAYMGNCAYACNYTN TAYGARGTNGAYTTYGAYGAYGGNTCNTTYAGYACNGAYATHACNCCNCARGAYATHAAR AGYMGNGAYTGYYTNAARGAYGGNCAYCCNTCNGTNGGNGAYGCNGTNACNATHCARTGG GAYGAYGGNAARACNTAYGGNGCNACNTTYAARAARGTNAAYGAYCARGAYACNTAYACN GTNGARTTYGARGAYGGNTCNATHYTNCCNGCNAARMGNAAYGARYTNTGGAGYAARTCN GAYGARATHCCNCARCAYATHAARAAYMGNATGTCNCARGCNACNGAY------AGYMGN TGYGARGARAARGARGARGCNGGNCAYGGNMGNMGNAARMGNACNAARGTNAAYTAYYTN AARATGYTNGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GTNAARTGYGCNYTN ACNAAYCAYGARATGCCNGCNAARGCNGARGCNATHAARAGYTAYYTNAGYGGNAARAAR TAYAARAARCARGCNGARATHGCNGCNTTYTCNTAYGARGARCAYAARCARCAYATHGTN CARAAYGARAARAARCAR------AAYGARATGATGTGYYTNYTNACNMGNMGNCAYYTN GARAARAAYCCNAARGCNATHCARMGNCAYATHAAYGGNMGNAARTAYAARAAYGCNYTN ATHMGNTGGAARGARTGYCARAARACNGGNGARAARTTYGTNCCNATHYTNMGNMGNMGN AARAARATHGTNGARAAYGARGAYGGNAARGARGTNGARGARGAYGAYAAYGARGGNAGY GAYGARGAYAGYTAYGARATGGAYYTNAAYGAYYTNAGYGAYYTNTAYCCNGGN------ ------ATHAAYGARATHGGNTCNGAYGAYAGYGARGARGARGARGARGARGARGAYGAR GARGAYGCNGAYYTNGARAARGARGAYACNYTNCCNACN------GCNAARAARCCNAAR TCNAARCARAARAAYCARAGYAARAAYAARGARAARCARAGYGARAGYMGNCARCCNGAR GARGARAARCCNYTNCCNCCNGGNTCNATGGGNYTNCCNTGGYTNGGNGARACNYTNCAR TTYTTYYTNAARGGNGCNTCNTTYTAYACNGARAARTTYCAYCARYTNGGNAAYATHTAY AARACNCAYGTNATGGGNCARCCNACNGCNMGNGTNACNGGNGCNGAYAAYATHMGNACN ATGATGGAYCARGARCCNGAYAARGTNGAYATGAARTGGCCNACNACNGTNAAYATHYTN ATGGGNGCNGARAGYYTNCCNACNGTNGTNGGNCCNNNNCAYNNNNNNYTNAARNNNCAN NNNNNNNNNNNNYTNACNCCNNNNMGNYTNNNNNNNTAYNNNCCNTGYATHNNNCARCAY NNNNNNNNNCAYYTNTCNAARTGGYTNNNNNNNGGNTCNYTNGGNGARMGNGTNYTNGGN TTYCCNGCNTGYGARGARYTNNNNGCNGAYNNNATGYTNGARYTNGTNNNNGGNTGYMGN NNNGARGAYGAYNNNNNNGGNAARGTNNNNGCNGCNYTNNNNGAYGTNAAYNNNNNNYTN TTYTCNGTNCCNATHAAYATHCCNTTYACNTCNTTYAAYAARGCNGTNAAYGCNMGNAAR ACNATHYTNGAYTTYGTNCARTCNMGNATGGAYAGYGGNGGNCCNGAYGCNGGNCAYGCN AGYATGATGGAYGTNYTNATGTCNYTNCAYGAY---------------------CCNGAR AARGTNAARGAYAAYGCNATHGGNYTNYTNYTNGCNGCNGCNGCNTCNACNGCNGGNGCN YTNACNTGYNNNNNNNNNYTNYTNGGNACNCAYCCNGAYGTNYTNNNNAARGTNMGNGAN GARNNNNNNAARTCNGGNATGATG------GANNNNNNNNNNNNNNNNNNNTAYGANTCN NNNCARNNNYTNGANTTYNNNNNNTGYGTNGTNAARGARTCNYTNMGNNNNYTNCCNCCN GTNGGNNNNTGYTTYMGNAARNNNNNNNNNGANNNNNNNNNNNNNGANTAYMGNATHCCN NNNGANTGGNNNGTNNNNTAYNNNATHMGNGAYACNCAYACNYTNNNNTCNNNNNNNNNN NNNGANGGNGANNNNTTYAARCCNGANMGNTGGCARNNNNNNGAYNNNNNNNNNNNNNNN NNNACNNNNNNNNNNGGNNNNTTYATHCCNTTYGGNGCNGGNAAYMGNATGTGYNNNGGN MGNNNNYTNGCNCARYTNATHNNNNNNATHNNNNNNGTNGARATNGCNNNNNNNNNNGAY TGGACNNNNNNNAAYCCNGANTCNCCNYTNGTNTTYYTNCCNATHACNAARCCNAARGAY GAYYTNCCNYTNAARTTYAARGTNYTNTCNGCNTTYMGNAAYYTNCAYMGNGCNMGNMGN GARGTNTTYGCNGGNGAYGARAAYGCNYTNAARGAYGTNMGNCARMGNATHAAYTCNGAR TTYMGNGARMGNYTNGGNGARGCNGAYCCNGTNAARATHGAYGARTCNYTNGTNATGGCN AARGAYGTNGCNTAYYTNYTNMGNTCNACNGTNGTNCARGTNCARCARAAR------GAY GAYGARACNTTYTCNYTNMGNATHACNAARAGYACNATHYTNCCNGARAAYACNCCNTAY GAYCCNACNAARGARATHCCNGCNAARCCNMGNAARAARAARMGNTCNGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATHGARCCNGAYAAYGCNYTNTGGAARMGNGAR MGNTGGCCNCAYCAYGCNGGNGCNATHMGNTGYTAYATGAARGGNCCNCAYGAYGGNGGN ATGCCNMGNGGNCCNAAYGCNAGYCCNGTNTTYTGYTCNGARTGYGAYTCNCCNGAYAGY CARTAYGAYTCNGCNAGYCCNAGYAGYATGTGYTGGGCNATHTCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CAYCARYTNTTYYTNCARACNATGTTYAAYAARGGNCARATGACNAARTCNGARYTNAAR GARAGYTTYACNYTNTCNMGNGARMGNTTYCCNGARCARGARATHAAYGAYAAYGTNATG AAYCARATHYTNCAY---------------TTYGTNGGNACNATHAAYAARGCNATHGCN CCNTAYGAYYTNGARATHAARAARGGNATHCARGARCAYGAYTGYTCNAGYGTNTAYTGY YTNGTNAAYACNGTNGARAGYCCNATHACNMGNYTNYTNTCNACNTAYACNGCNAAYGAR YTNGARYTNTTYAARAARATGGTNGARTCNATHGTNGARTCNGAYGARGGNAARATHGGN TCNMGNAAYGCNYTNAAYYTNACNGARAARYTNCARAARMGNATGGGNYTNGARGARGCN CARAAYTTYTTYAAYTCNYTNGARMGNGARAARTGGATHATHAARGGNGARGAYGGNACN YTNGCNYTNTCNATHMGNACNATHYTNGARYTNGAYCARTAYYTNCARGAYYTNTAYCCN GAYYTNGTNAARAARTGYAAYYTNTGYAARAARATHTGYYTNATGGGNGARTCNTGYGTN GAYTGYGGNATHAARATHCAYMGNATGTGYTCNMGNAARYTNTTYACNGARATGCCN--- GARAARAARTGYCCNAGY------TGYAARAGYMGNTGGTCNGAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGTAYATHAAYAARTCNYTNTCN TTYYTNGARCARGTNGTNATHGCNYTNGCNTCNAARTCNMGNGAYCAYGTNCCNTTYMGN CARTCNAARYTNACNCAYTTYYTNAARGAYTCNATHGGNGGNAAYTGYAAYACNGTNYTN ATHGCNAAYATGTGGGGNGARAARGCNCARYTNGARGARACNGTNTCNACNYTNMGNTTY GCNACNMGNATGATGTGYGTNGCNAGYGARCCNGCNGTNAAYGARATHTAYGAYCCNGCN YTNYTNGTNAARAARYTNCARAARGARATHTGYCAYYTNAARTCNGARYTNGCNATGCAY GAYACNYTNACNAAYMGNAGYATGATHACNTAYGAYCCNYTNTCNGARCARCARAARTAY GARATHMGNACNCARGTNMGNMGNTTYYTNGARGGNAGYYTNGAYGARATHGAYATHGTN AAYATHMGNCARATHGTNGGNACNTTYGAYACNTTYAARCARYTNTAYCARGAYATGGAR AARGARATGGARGCNAARYTNAARGAYAARTAYATGYTNATHGAYAARACNGAYCCNGCN TCNATHGCNGCNGCNCARCAR--------------------------------------- ------GCNGGNGTNCCNATHGCNGAYGAYGGNACNTAYGTNGGNGARYTNGARGGNGGN AGYTTYGGNGTNGGNTCNGCNCCNAARAGYGCNAARGGNGAYACNTCNGCNGTNGTNCAR YTNAARAARAARGARMGNGARMGNGAYMGNAARMGNGGNTCNMGNGGNGCNAGYAGYCCN ATHGCNGGNAARACNGCNTCNAGYCCNTCNCARAGYGTNAARGGNGARMGNAARGARGAR TCNCCNCCNACNCCNGTNGGNGARMGN---------CCNGARAARGARCARGARGGNTCN GCNTCNCCNGTNAGYTCNACNGGNAAYYTNTCNMGNGCNGAYMGNAGYCARMGNCCNAGY ---------------------------------------------------ACNCCNCCN ACNMGNAGYTCNGCNTTYGARGARTTYAARACNGAYMGNGGNAGYGARATHAAYMGNATH YTNATHGARAAYAARGARATHYTNTCNACNGCNAARAARACNTAYTCNAAYYTNGCNAAR GARATGAAYTCNYTNAARACNAGYATHGAYAARTCNMGNCAYMGNYTNGAYGAYYTNAAR GTNYTNMGNGARTCNGARGGNCCNATHYTNAAYGARGAYGGNGAYATHGTNATHAGYGAR GARGARTTYCARGARATHAAYAAYYTNMGNGAYYTNAARATGTCNTAYMGNGTNAARMGN GAYGAYYTNGCNAARACNGARTCNGARGTNAARTAYTGYCARAARYTNGTNGAYCARTGY MGNYTNMGNYTNATHCARGARTTYGAYAAYTGGTAYAGYGARAGYTTYYTNACNTCNGCN GAYGAYAAYCARACNAGYYTNGGNGTNGGNACNGGNGTNMGNCCNGGNGTNATGYTNCCN ATHACNAGYYTNACNAAYGARGAYGARCARGARAARTTYGARMGNYTNCARYTNGARYTN ATGATGAAYAAYCCNGARTCNGCNGCNTTYTAYAAYGCNCARATGMGNACNTCNMGNMGN AARATHTAYGGNCARGCNYTNAAYCARCCNCARCCNGCNTTYMGNMGNCARCCNGGNACN CCNACNATHAGYTTYMGNAAYCARCCNCCNGGNATHATGCARGTNCARTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARAAR------------------------ATHGCNGCNGARATGAAYYTNTCNGARACN GCNTTY------ATHAARACNAARGAYATGGAYTTYACNTCNGGNAGYCARTTYTCNYTN MGNTGGTTYACNCCNACNACNGARGTNAAYYTNTGYGGNCAYGCNACNYTNGCNTCNGCN GCNGCNYTNYTNGAYGCNGCNGGNAAYGARAGYTCNAARATHGAYTTYGARACNAARAGY GGNACNYTNTCNGTNATGMGNCAYCCNAAYAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CAYGGNGAYGTNAARCCNGAYAAYTTYYTNYTN MGNGARYTNCCNYTNYTNTGYGARAGYAGYGAYCCNGCNAARGTNTTYGGNTCNCAYYTN MGNGTNTTYTGYYTNACNGAYTTYGGNCARAGYATHGAYATGMGNYTNTAYCCNGAYAAY ACNGCNTTYAARACNCARGTNACNACNGARGGNTTYGARTGYATHGARATGMGNACNGGN YTNCCNTGGACNTAYCARACNGAYYTNTTYGGNYTNGCNGGNACNYTNCAYGTNYTNYTN TTYGGNAGYTAYATGAAYGTNTTYGTNGARAARGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGNACN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYACNAARTTYTGYACNAAYTGYAARAARGAYATHTCN GCNAGYAAYTTYGTNATGCAYGARATGCAYTGYMGNMGNCAYATHGTNYTNTGYGAYTTY TGYAARGARCCNATHCCNMGNTCNGARYTNGAYCARCAYTTYAAYGAYATHCAYAARAAR GTNCCNTGYGAYYTNTGYCARGTNGAYGTNGCNAARGARGARATGGARGAYCAYAARAAR AAYGTNTGYTCNAARGCNCCNGTNCAYTGYGARTTYTGYGARYTNTCNATHGCNMGNGAY AGYGTNGARTCNCAYATHGAYTAYTGYGGNAGYMGNACNGAYTGYTGYCCNYTNTGYCAR CARTAYGTNATGYTNAARGAYATGATHMGNCAYGARAGYTCNGGNTGYAGYTAYCCNGAR CCNAARCCNCCNTCNAAYACNTCNACNCARGAYCCNTTYAGYATGTCNCAYYTNCARGAY TTYYTNGARACN---GAYTTYGGNAGYATHYTNGAYATHCCNGAYYTNTCNGCNGAYYTN MGNMGNGARYTNYTNMGNAAYCAYAAYGTNCCNTCNCARGCNACNMGNTCNTCNACNGGN AAYGCNTCNAAYACNMGNMGNCARAAYAAYMGNTCNAAYGTNTAYGCNAAYAARCARMGN GAYGCNGTNAARMGNAGYTCNAGYCCNCCNGAYATGGAYTAYGAYTGYATGYTNGCNYTN CARGTNGCNCARGARGARATGCARAARGAR------TCNGARCAYGTNGGNGTNGARGAR GTNGCNMGNGCNAARTGGATHTGYYTNAAYAARATHTCNTAYAARGAYCCNAAYGGNACN YTNMGNATHTGGGARGGNGTNTCNMGNACNACNMGNAGYGCNGGNGARGCNGAYGCNGTN GGNATGATHGCNGTNTTYCAYGAYCCNATHACNGAYCARGARAGYGTNATHYTNATHMGN CARTAYMGNCCNTCNATGCARACNTAYACNATHGARTTYCCNGCNGGNYTNATHGAYGCN CARGARACNGCNAGYCARGCNGCNGTNMGNGARATGGARGARGARACNGGNTAYAARGTN TCNGCNGTNGCNGTNTCNCCNGCNACNTCNYTNGAYCCNGGNGTNGGNAAYACNACNYTN AARYTNGTNACNTGYCARGTNGAYACNTCNAARYTNAGYAARACNGARMGNCCNAARCCN ACNGGNGGNGAYGCNGAYGARTTYGTNCARGTNATHGTNGARCCNGTNAARACNYTNATG CARAARYTNGARGGNTAYGCNTCNMGNGGNGAYTGYGTNGAYTCNMGNGTNTAYGCNTGG GCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNCCNCARATHGTNATHCCNTCNTAYGTNGCNGCN ATGAAYGARCCNCARYTNTAYGCNGCNCCNGCNATH---TAYTCNTCNCCNGCNGCNGAR YTNGTNGCNGCNCCNAGYGTNACNCARACNGARCCNACNCAYGCNCCNGARGAYACNGAY AARGGNGCNAARAARAARAARAARGAYAARGCNGGNAARGARAARTCNYTNACNGCNACN TCNAGYATHATGATGAARAARAARMGNGTNTCNTCNATGGTNCARAARTGGCARCARGTN AARAARCARGTNGARAARGARGAYMGNGCNAARGARYTNMGNCARGCNGCNATHMGNGAR AARATHAAYCARYTNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MGNGAYATHATGCAR ACNYTNTCNMGNTAYTAYAGYAAYGCNTTYTCNGAYYTNGARAARCARCARGCNTTYAAY YTNTTYYTNGGNGTNTAYGTNCCNAARGARGGNGGNCCNAAYYTNTGGGAYYTNCCNACN GAYTAYTAYYTNCAYAAYACNGTNTCNYTNGGNGTNCCNATGACNMGNCARAAYTAYTGY CARTGGTGGGAYTCNGARGTNTGGGAYTCNYTNCCNYTNCCNMGNGAYGARGTNAAYAAR CCNAAYATHGTNCAYACNGCNGTNYTNACNGCNCCNCARMGNGAYGARCAYGTNAAYTCN TTYTAYGARCAYTAYMGNCCNGAYGARYTNTCNGTNTTYGAYGARATGTAYCARATGTAY YTNTCNCARGCNTGYTGGAARCAYYTNCCNAARCAYTCNAAYGARTTYAGYCCNTTYTGY GTNMGNCAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GCNAAYGARCARTTYGTNGARGARAAYTTYCARAARGCNATHGAYYTNTAYACN GARGCNYTNTCNCAYGAYGAYCARMGNGAYGAYATHTAYTGYTTYMGNGCNAARGCNTAY YTNGCNYTNGCNAAYAAYACNGCNGCNATHCARGAYTAYGAYAARGCNATHAARATHAAY CCNTCNAAYCARAARGCNTAYATHAAYAARGGNTCNATHTTYYTNAARATGGAYGARGTN ACNCARGCNGARAGYGTNTTYAARGARGGNMGNACNCARTGYCARAAYGGNCCNGAYTTY GAYGAYTGGYTNTCNAARGTNGARGTNMGNATGMGNGARYTNGGNATHGGNMGN------ ---------------------------------AGYAGYYTNCCNCCNAARYTNAARTAY AAYTGGTAYCARACNCAYACNCAYGTNGTNGTNACNGTNYTNGTNAARAAYYTNAARAAR GARGARYTNCAYGTNGAYGTNAAYGCNAARTCNGTNCARGTNTCNATHTCNMGNGGNGAR GARTCNAGY---CARYTNTCNYTNACNYTNGCNCAYCCNGTNTCNCCNGAYCARACNCAR ACNAARYTNTTYTCNACNAARGTNGARTTYAARYTNAARAARYTNGARGGNGTNCARTGG GCNAARYTNGARGGNTCNCCNGAYGARGTNGARACNAGYATHYTNCCNCCNTGYGCNGCN CCN---CARAGYGTNGARGCNCCNMGNTAYCCNAGYTCNTCNCAYCAYTCNMGNGAYTGG GAYAARYTNGCNGCNGARGTNACNGARGARGARAARAAYGARAARYTNGARGGNGAYGCN GCNYTNAAYCARTTYTTYCARAARATHTAYGCNGAYGCNTCNGAYGAYACNAARAARGCN ATGATGAARTCNTTYTCNGARTCNGGNGGNACNGTNYTNAGYACNAAYTGGTCNGARGTN GGNAARGAYAARGTNGARGTNAARCCNCCNGAYGGNATGGARTAYAARAARTGGGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TGGMGNGARATGGARACNGCNGTNCAY GAYGGNYTNACNACNGGNATHGGNGTNTCNAAYTTYTCNGTNGCNCARYTNMGNGAYGTN YTNAGYGTNCARMGNGTNCCNGTNTCNAAYGTNCARTCNGARACNCAYATHTAYTAYCAR CARTCNAAYYTNAARMGNGTNTGYGAYYTNAAYGCNATHGTNATGTCNGCNTAYGCNCCN YTNGGNTCNCCNGGNMGNCCNTCNCAYCAYATHYTNAGYGAYGARTCNYTNYTNAAYGAY CCNGTNGTNTCNTGYATHGCNAARACNTAYAARMGNACNAAYGCNCARGTNYTNYTNAAY TTYYTNYTNGGNTGYGGNTTYGTNGTNYTNCCNAARAGYTCNAGYATHAARMGNATHCAY GARAAYTTYGGNTGYYTNGGNTGGACNYTNGAYACNGARGAYTTYAAYGARYTNMGNAAR YTNGAYMGNAAYGTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNTGYCCNACNATGTCNYTN TTYYTNCCNCAYCARTGYCCNGARCCNYTNGGNAARAAYAGYGCNCCNYTNTGYATHTCN TCNMGNATGYTNGAYMGNCARATHMGNGCNCCNCAYGGNGGNCCNAAYGGNCARAARYTN AAYMGNMGNTAYYTNCAYAGYMGNATGAGYACNGTNACNTAYTTYMGNGAYTCNACNGGN GAYGGNYTNGCNTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNGARYTNAGYGCNAAY GTNAAYGCNTGYGAYAGYGARATGTGGACNCCNYTNCAYGCNGCNGCNACNTGYGGNCAY GTNACNYTNTGYAARCAYYTNATHGAYMGNGGNGCNGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGNTTYTCN TTYGGNTCNGCNACNACNTCNGCNACNTCNGGNGGNTTYTCNTTYGGNTCNACNGCNACN ACNTCNGCNACNCCNGGNTAYTCNTTYGGNTCNTCNACNGCNGCNGCNTCNACNGCNGCN GGNGGN------------TTYTCNTTYGGNACNTCN------------ACNCCNGCNACN ACNACNGCNTCNTTYGGNAAYTCNGGNTTYTCNTTYGGNACNYTNGCNGCNAARACNATG GCNACNACNCARGCNGGNAGYTCNCARGGNGGN------------GAYGAYGARGARTAY GTNCCNCCNAARCCNGARGTNAARGARATHGCNGARGARGGNTCNYTNTAYTCNAARMGN TGYAARYTNTTYTAYCARAARGAYGGNCARTGGACNGARMGNGGNGTNGGNAAYATHCAY ATHAARCCNGTNGAYGARTCNAARACNCARYTNYTNGTNMGNGCNGAYACNAAYYTNGGN AAYATHYTNYTNAAYGTNATGGTNAGYTCNGGNYTNCCNGCNTCNMGNCARGGNAARAAY AAYGTNYTNYTNGTNTGYATHCCNAAYCCNCCNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CCNAARGAYTGGATGAAYATHTCNAAY ATGGCNCAYTAYATGAARTAYGCNATGGGNAGYTAYGGNTGGCCNTTYTAYATHTAYGAY CAYYTNGCNACNGGNYTNTGYMGNYTNTGYTGYYTNTGYCAYTGYTGYTCNTGYYTNMGN AARGCNAAYCARATHTTYGARGAYAAYTGYTGYCARTGYAAYACNGCNGCNATHAARAAR YTNTCNGGNYTNCAYAGYACNGAYYTNATHTAYGTNACNTTYCAYAAYAARTTYAARGAR ATHCCNTAYTAYGTNGTNGTNGAYAARGTNAARAAYACNGCNGTNATHAGYATHMGNGGN ACNYTNTCNYTNMGNGAYGCNYTNGCNGAYGTNACNGCNGARGGNGCNGTNYTNGARATH GARGGNGTNGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYTCNGCNGTNGCNTGYATGGGNGAYAARYTNAAYGGNTGGTTYGGN GAYYTNMGNGARAAYGTNYTNGGNCARYTNGTNTCNTCNYTNATGGARACNYTNGAYGCN AARTGYGAYGARCAYAARAARTAYACNATHGGNYTNCAYGCNGAYAARGCNCAYYTNCAR AARGARGTNAAYMGNYTNAAYTGYMGNATHAAYACNYTNGARCAYGAYYTNACNCARAAR AGYTCNYTNGTNAARAAYYTNACNGAYTCNYTNGTNGCNCARAARGAYAARGTNTCNACN GCNAARCARTTYTAYAARTGGAAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ACNAARMGNAARTTYGGNYTNATGAARAARGCNTAYGARYTNAGYGTNYTNTGYGAYTGY GARATHGCNYTNATHATHTTYACNAGYAAYAAYAARYTNTTYCARTAYGCNAGYTCNGAY ATGGAYAARGTNYTNYTNAARTAYACNGARTAYAAYGAYTCNGTNGAYAGYAARACNAAY AARGAYATHATGGAYATGYTNAAYAARAARGAYACNAARGGNGGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGTCNAGY GAYTCNTGYTTYAARTGYGGNGGNMGNGGNCAYTTYGCNMGNGAYTGYMGNAAYCCNCCN GCN---------------------------CARAGYCCNMGNCCNATGAAYCARGGNCCN TCNGGNGGNCARAARTGYTAYAARTGYAGYMGNGTNGGNCAYTTYGCNMGNGARTGYCCN CARGAYCARGARMGNTGYTAYAARTGYAAYGGNYTNGGNCAYATHGCNAARGAYTGYGAY AARCCNATHTCN---ACNGGNGCNTGYTAYAAYTGYGGNTGYAGYGAYCAYYTNCARMGN GAYTGYAAYCARGCNATHGTNAARTCNTGYTAYMGNTGYGGNCARTCNGGNCAYATHTCN MGNGAYTGYTCNGCNGGNGGNGGN------------TTY------------GAYGAYMGN AARTGYTAYACNTGYGGNGGNGTNGGNCAYYTNTCNMGNGARTGYCCNACNCCN------ ------MGNAARGARTGYTAYMGNTGYAAYCARACNGGNCAYYTNCARAARGAYTGYCCN AAYGGN---CARAGYAAYACNCARTGYTAYAAYTGYAAYGARATHGGNCAYATGGCNMGN GAYTGYACNGCNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TTYGCNTCNAARYTNCARGGN CAYGGNGTNCAYGCNACNMGNYTNCCNGTNGARGTNAAYYTNGAYCARMGNGCNTGGYTN AGYMGNAGYYTNACNGARTTYTAYCCNCCNATHATHGCNAAYTCNAARATHAGYMGNGCN GTNTTYGAYTTYCAYGGNATHGCNTAYTCNGAYGCNTTYTTYGGNYTNTCNACNATGGGN MGNGAYATGACNGTNCARMGNYTNCARCAYGGNATHYTNGARGCNTTYCARGGNGCNGAR GARMGN---AGYGAYCARACNAARGAYTTYACNTCNTGYGARYTNATGAGYCAYCCNGGN TAYGCNACNCCNGAYGAYGGNCARGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNCCNGARCCNGARCCNGAR CCNGARCCNGARGTNCCNGCNGGNCCNCCNCCNCCNAARCCNGGNGAYGARGARTGGGAR TTYGTNGAYYTNGAYATHAAYATGGARYTNGCNAARGTNYTNGTNYTNCAYTGGGARGAR ACNGARAARACNTAYGTNAAYAGYAGYAARCAYGTNTTYMGNAAYATHMGNCARGARMGN GARAAYATHTAYMGNTAYTTYTTYCARATHMGNAARGAYTTYYTNCAYTAYYTNMGNMGN CCNGAYTGYAARCARGAYTAYGTNTCNCARTGGCARAARACNTAYAAYGARGTNTCNGAY GAYATGMGNGARGAYGARGARACNMGNGCNGARYTNCAYCARCARGTNGAYGAYYTNMGN GARMGNYTNTGGAAYATHTGYGAYGARMGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNYTNCARCCNYTNGCN---GTNGCNYTNTTYMGNAARGCNGGNAARTCNYTNCAYACN ACNTCNMGNAARTCNGGNGARGCNYTNTAYMGNGARAARATHTAYGARTAY------AAR GARCCNATGTAYATGCARTAYGCNGGNACNGGNYTNAGYGCNTTYATGTGGTAYTGGATH YTNTAYCAYTGYTAYTTYGARTAYGARCAYYTNGTN------------------------ ---------------------ATGCCNGGNGARGAYCAR---GTNTTYGTNGARAARYTN GGNGARATHCCNYTNATHAAYGAYGGNTGGACNACNGCNACNGGNTAYTAYTCNMGNYTN AARGAYTAYAAYTCNYTNATGAAYYTNGCNYTNTCNGTNGCNGARTCNAGYGTNAARGTN GCNGGNCAYGTNACNTCNCCNGTNYTNAGYCAYTAYCARCCNCARATHGAYAAYATHAAY GAYTAYGCNTGYAARAARYTNGAYGARYTNGARTCNAARTAYCCNGTNATHAARCARCCN ACNGARCARTGGAARGARGCNTGYGCNGGNTAYGTNCARCCNGTNGTNAGYCARGTNAAR CCNGTNATHAGYCARGTNCARGGNATGGTNAAYAAYGGNAARCARAARATHGTNAAYATH AARACNGCNAGYACNAAYATGGTNTCNGARGCNMGNAAYYTNGGNGTNGGNACNGCNACN CAYGTNTTYAAYTCNACNTTYGARACNGCNCCNGGNMGNTTYATHACNMGNACNGTNGAY GGNGCNYTNAAYGTNGCNGAYGGNYTNGTNGAYAARTAYYTNCCN--------------- GARGARAARATHGARACNCCNGAYACNGAYGAYATGAGYACNGAYGAY------GAYAGY GAYAGYGAYCAYGARATHGARGARATGCARGARATGGAYCCNACNCCNCARMGNGTNATH ATHCAYGCNGGNAAYGTNACNGARAARATHMGNAARMGNATGTAYMGNMGNGCNATGAAR GAYYTNACNTAYGCNMGNGCNCARACNTCNGCNGCNYTNAGYMGNATGCARAARACNGTN ACNYTNATHGAYTAYGCNAARGAYAAYATGAAYACNGCNAARGAYAARGTNGARGARYTN TGGGTNGARATHACNAARGAR---------GCNGGNGCNTCNTCNGARGARAARACNGTN TTYGCNGGNACNGTNGARGAYMGNATHATHGCNYTNGGNMGNYTNGCNACNMGNCARGTN AARTCNAAYGTNGCNACNTTYGARAARATGGTNTCNGARATHGGNGARTTYGGNAARAGY CCNATHTCNAARACNAARGARTAYAARGAYYTNATHTCNACNTTYYTNTCNGTNGARTCN ATHCARAAYTTYTCNTCNCARAAYATHGCNMGNGCNACNGARTCNYTNAARTCNYTNCAR GARAARGTNTAYAGYATGGTNACNAGYYTNMGNTCNATGGAYTGGATGGGNATGGAYTTY GAYYTNGARAAYATHTCNYTNGAYGAYAGY------------------------------ ---CARGCNTTYYTNYTNMGNCARAAYTGGAARGCNGTNATGMGNAAYGARACNGARTTY GGNGTNGAYYTNTTYATHMGNYTNTTYAARACNAAYAARGAYYTNCARTCNYTNTTYCAR GGNTTYAARGAYATHAGYAGYGAYGAYGARYTNMGNTCNAAYGARGCNYTNGARTAYCAY GCNACNATGGTNATGACNACNYTNGAYGAYGCNATHACNCAYATHGAYAAYTAYGAYTTY GTNTGGGARYTNYTNGCNCARACNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CARGAR ACNCAYMGNYTNTCNGARCARYTNATHCARYTNATHGGNAAYGGNMGNCCNAAYGARAGY GAYGARAGYTTYGARGCNYTNATHGARAARGGNGCNGAYGTNAAYMGNCARCAYGGNACN YTNYTNCCNYTNCARTAYGCNTGYTGYYTNGGNGARAARCAYATHYTNCARYTNYTNATH MGNCAYGGNGCNAARGTNAAYAARCCNGAYGGNTAYAAYMGNACNGCNYTNCAYTAYGCN GCNGARMGNGAYGARCARTGYGTNCARATHYTNYTNGARAAYGGNGCNAAYCCNAAYYTN GGNGAYMGNAAYGGNAAYACNCCNYTNCAYTGGGCNACNTAYAARAAYAAYGTNYTNTGY GCNGARMGNYTNYTNCARTAYAAYGCNGAYGTNAAYAARGTNGAYTTYAAYAAYGARACN CCNYTNATGTGGGGNGCNAARAARGGNAAYYTNGAYGCNATHMGNYTNYTNYTNGAYTAY AAYGCNGAYGTNGAYATHTGYAAYATHCAYGGNCARAAYGCNYTNGARAARTCNGCNGCN YTNCARGCNAGYGGNYTNAAYGGNCCNGARGAYGARGCNTGYGTNACNYTNYTNACNAAR GCNTCNGGNCAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CARTTYGGNCARGTNGAYGTNATGGTNAAY AAYGCNGGNATHYTNAAYGARGCNMGNTGGGARCARTCNATHYTNATHAAYTTYACNGCN ACNATHCARGGNACNAARYTNGCNATGGARCAYATGMGNAARGAYAARGGNGGNAARGGN GGNMGNATHGTNAAYATHAGYTCNATHATGGGNYTNACNATGCAYTTYTCNCARCCNGTN TAYTGYGGNACNAARCAYGCNGTNMGNGCNTTYACNACNTCNACNGCNATGACNCCNGGN YTNCAYTCNGARATGGGNATHGARGTNGCNYTNYTNTGYCCNGAYGTNGCNAAYACNGAY YTNATHACNAARYTNGAYGAYGAYMGNATHCAYGGNYTNAGY---------------YTN ACNGAYGTNATHGARYTNCAYAARATGCCNATHCARACNGTNGTNGAYGGNYTNTTYTCN YTNYTNCAYAARGARGCN---ATHAAYGGNGCNATHYTNYTNGTNACNAARAAYCARATG TCNTTYCARAARATG--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GCNGTNATHGCNTCNGTNGCNGTNTTYATGYTNYTNATHGTNATHGCN TCNATHGTNTAYGCNYTNTCNGCNAAYTCNTGGATHAARTCNGCNAARAARTCNGAYGGN AARYTNAARATGCCNMGNTCNTAYTTYGARAARAARMGNGARATHAARTAYAARATGGCN GCNTCNACNMGNTCNMGNGCNACNCARGAYATGCCNTCNATGMGNCCNCCNYTNCCNCCN GTNCCNACNGGNCCNGCNATGACNAAYGARTCNAGYGTNCAYGTNTGGAAYACNGARGCN AARACNTAY---------TAYGARGARAARGGNGGNACNGTNGARYTNGGNGAYGARGAR GAYGARGARTTYCAYATHGARACNACNYTNGTNGAYAAYGARGTNYTNGAYGTNGGNCCN TAYCARGGNGTNTCNTCN---GGNACNGCNCARCCNGTNGAYGGNAAYGTNTAYTCNAAR CCNTAYYTNTTYTCNAAYCARGAYMGNATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CARYTNAARACNMGN ATHCARGCNGARGARCAYYTNMGNAAYATHGARMGNAAYMGNGGNMGNGAYCCNGAYTTY TTYTGYAARATHTGYAAYAAYGAYYTNACNGTNCCNTGGGARAARCAYMGNTAYTCNAAY ATHCAYAARCARMGNYTNYTNCARGTNMGNAARGGNTGYGGNTGGTGYAARGTNCAYGAY TTYACNAAYTTYACNGARGTNYTNGARCAYMGNGARACNGARCARCAYAARAARAAYGCN GARYTNTAYGGNAARAARGAYGARGGNAAR---GARTCNAGYCARGCNGARGAYGCNAAR AARGCNGAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN TCNYTNGARAAYCARGTNTTYMGNGCNTTYYTNGCNTAYGCNGGNYTNGTNATHGTNAAR ATGATHGGNATGTCNTTYATHATHGCNTTYYTNMGNGTNACNAARAARGTNTTYGCNAAY GARGARGAYACNGTNTTYGGNATGCCNTCNAARGAYAARAARACNACNYTNAGY---AAY ---CCNACNGTNGARMGNGTNMGNMGNGCNCAYYTNAAYGAYYTNGARAAYATHATHCCN TTYGTNYTNYTNGGNTTYYTNTAYATHACNACNAGYCCNGCNYTNGCNTCNGCNYTNYTN CAYTTYMGNATHTTYGCNGTNTCNMGNATHYTNCAYACNGTNTCNTAYYTNTTYAARATH CCNCARCCNGCNMGNTTYTTYTGYTTYYTNTTYGCNATHTGYGTNAAYGTNTCNATGGCN TAYCARGTNATHTCNAGYGGNACNTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN YTNCAYMGNACNGARGARGTNYTNGGNYTNTGGMGNYTNYTNATHGAYCAYCARTTYCAY GTNYTNACNGCNGCNATGGCNTCNGAYATHCARAAYCARYTNMGNAAYATGACNTTYAAR ACNYTNGTNACNGGNGGNAARGAYGTNTGYAGYACNYTNATHYTNTGYYTNGTNACNMGN TAYYTNAAYGAYAAYGCNACNATHGAYGCNATHAAYGAYAARYTNMGNGARGTNTGYCCN AAYYTNTAYAGYACNGAYGAYGCNACNTGYTCNAARTCNAAYGARYTNYTNCARGCNGCN AARTCNAAYCCNAAYCARGTNGARAARGARMGNCARYTNCARGARGCNYTNCARYTNYTN AARAGYGTNTCNCARCCNYTNAAYYTNACNGTNATHTGYTCNCARYTNGCNAGYGTNCAR TTYTAYATGGGNATHGTNGARYTNGGNYTNAAYGARGCNYTNAARAGYGAYCCNCARGGN ATHGCNGTNCAYTTYTAYAAYAGYGGNGARCCNCARGARGAYGTNCARGGNATGCARGCN TAYATHGCNMGNATGGAYTGYTAYAARTGYATHACNGAYACNYTNACNTTYYTNTGYGCN GCNAGYAAYAGYCARGCNCARGTNCCNGCNAAYTCNTTYATGGCNACNTCNCARAAYCCN ATGGARGCNAAYAARATGGARCCNCAYCARGCNGARCARTTYAARGARGARGTNTTYCAY ACNGCNYTNMGNTGYGAYGAYTCNYTNTTYCAYGCNGCNYTNTAYGARTGGYTNTTYAAY ACNAAYCARGCNGARAARYTNYTNGARATHAAYACNCCNTAYGTNGARCARTAYYTNMGN MGNAARGTNAAYYTNGARACNGAYAAYACNAGYGCNYTNGAYATGYTNTGGMGNCAYTAY GARAARGTNGARAAYTTYCCNGCNGCNACNMGNATHYTNTCNCARYTNGCNGARMGNCAY GGNACNTCNGTNAAYYTNACNCARMGNYTNGARTAYYTNTCNMGNGCNGTNGTNTGYGCN AARAGYTCNACNTCNMGNYTNGGNACNTCNGCNGGNGGNGARTTYYTNCAYGARYTNGAR GARAARATGGARGTNGCNMGNYTNCARATGCARATHTAYMGNAAYYTNAGYACNATGACN AAYTCNATHGCNGTNGARGGNGCNAARGCNAARYTNGAYGCNGARYTNATGGAYATHACN ACNYTNTAYGARGARTTYGCNGAYCCNTTYGAYYTNCARGARGTNAARYTNGCNATHGTN CAYTGYGCNGGNYTNTAYGAYATGGCNYTNATHGARGAYYTNTGGCAYAAYATHATHAAY AARGARATHAARAAYACNGCNCAYYTNTCNGGNGGNGAYMGNATHACNACNGTNAGYACN AARYTNAAYACNATHGCNAARATGTAYATHAAYGCNGARMGNTAYTTYCCNATHGCNYTN ATHYTNMGNCAYYTNGARCARAARTCNTGYGARATGGGNGTNGAYYTNGARTGGGTNTTY AARYTNATGYTNGAYGTNGGNGTNGCNCCNGCNAARYTNYTNGARYTNTAYGAYMGNGTN TAYAARTCNAARGAYGTNGTNTGGCARACNYTNAAYCARCCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ACNCCNAGYACNCCNMGNCCNGARGAYGTNCARTGYAAYATHACN TAYATGGARGTNMGNMGNYTNGGNGGNACNTGYATHCARTAYGGNGCNCCNTGGGTNTGY CARTCNGGNGARGTNGCNGARYTNAGYMGNCARTGYCAYCARYTNGCNGCNMGNCARGCN GCNCARMGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNAARGAYTTYCAYATHCCNGTNACNGTNGCNAARGGNMGNGARAARGTNMGNGARATG TTYYTNAARAAYAARCAYGTNACNGAYATHMGNGTNATHGAYATGYTNGTNATHAARGGN CARATGGAYYTNGTNGARACNGCNAAYATHTGGAARCARMGNAAYCAYGTNATGATGTAY TTYCARGAYACNGTNAAYCCNAARCCNACNGAYTTYYTNGGNAARTTYTAYGARGGNCAR GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATHGTNGTNGGNATH GARGARCCNAGYACNAARGCNGARAARAARAARAARAARCARAARGAYAARGCNAARCCN ATGTCNGTNGARGARTTYAAYAARYTNCCNCCNCCNGTNMGNAARACNTCNAGYTCNGAY ---GAYCCNGAYGCNGAYACNGARCCNTCNAARCCNCCNGTNCAYTAYACNATHCCNCCN GCNGARAARGAYGCNAAYTTYTTYAAYAARGTNAARAAYGAYGCNGARGAYATHYTNAAR CARGAYMGNATGCARGARGARTAYMGNAARACNTAYTCNGCNGAYAAYGTNGTNATHGCN AARYTNAAYCAYGAYYTNGAYYTNAARGAYCARAARATHGCNGARYTNACNGGNCARATG GARAARATGGARGCNAARATGAARCARGTNAARCARMGNAAYAARCARYTNTGYTTYATH YTNGGNCARGGNGARATGAARGAYAARGCNCARGCNYTNATGCARGTNGARGARYTNAAY AARGTNAARGAYGARYTNACNGARCARGTNACNTCNYTNACNGCNGARYTNGARAARGAR AARTCNAARAAYMGNGCNYTNAARACNGARTCNGAYAARATHAARGGNAGYAARCARGGN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------MGNTTYGAYTGYYTNTAYTGYACNGAYMGNTTYTCNAGYACNTCN YTNTCNGAYATHAARCARCAYTAYTCNGTNGARCAYCCNGAYCARYTNYTNGTNGTNMGN GAYYTNGARGCNAARAARGARAARYTNGCNTCNMGNGTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNGGNYTNYTNCCNAARAARCAYYTNGGNATGGAR YTNGGNGARATHTTYCCNCAYATGYTNAARATGMGNGAYAARTAYGGNYTNAAYGARTGY GGNGARGGNGGNGARTAYGARACNTTYGTNTTYGAYTGYCCNYTNTTYAARAARTCNATH GCNATHGGNGARACNGARYTNGTNATHCAYTCNGAYGAYGCNTTYGCNCCNGTNGGNTAY YTNAAYYTNAARCAYTGYCAYYTNCARGAYAARCCNGGNCAYGAYGTNAARTGYTTYATG AARAAYYTNGAYCARATGCCNATHYTNACNACNCCNAARTGGATH--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GCNGCN CAYYTNYTNGCNCARGAYCARTCNCAYTCNYTNCARGAYGARYTNAARGAYYTNAGYMGN GTNAARGCNACNATHGCNAGYCARYTNGCNGARGCNTCNGCNAARAAYCAYGAYYTNAAR CARGCNYTNGTNGARATGCARCAYMGNGARAARGCNGCNMGNGAYGARGTNGAYATGTAY AARAARCARYTNTAYCARGARMGNAAYGGNYTNAGYAARAAYTAYGARACNYTNAARCAR GARYTNAAYGARGCNAARGTNMGNGARGCNAAYYTNYTNCAYGARGCNCARCARAARTTY MGNGCNACNAAYGCNGARACNGAYGCNACNATHCARGCNYTNAARATGGCNGTNTCNGAR GARAARTCNAAYAGYAARATHGCNCAYMGNAAYGCNGAYMGNATGAARGARGARYTNACN GTNYTNGARAARMGNTTYAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY TTYCARACNAARCCNAGYYTNMGNAAYCCNTTYMGNGAYGARGCNTTYGTNGGNGGNTTY YTNMGNMGNAAYATHCCNGAYCARAARATHTCNAAYGTNCARGAYGAYYTNACNMGNTTY GGNGAYMGNGTNGCNGGNGARYTNTTYGARYTNTCNGTNCARATGGARTCNGARCARCCN AARYTNGARCARTTYGAYGCNTGGGGNCAYMGNGTNGAYMGNYTNGTNACNTCNAGYGCN TGGAARAARATGAARGARGTNTCNGCNCARGARGGNYTNGTNGCNATHGGNTAYGAYAAR ACNTTYGGNCCNTGGAARMGNYTNTAYCARTTYGCNAARTTYTAYYTNTTYGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYYTNGTNGTNGGNYTNGGNAAYCAY CCNTAYCCNGARACNMGNCAYAGYATHGGNATGAARACNATHGAYCARYTNGCNAARACN YTNGGNYTNAARTGGGARAARYTNCCNGGNMGNMGNGGNGGNAGYATHTGYCARTCNGTN YTNGCNGCNAAYAAYGAYCAYMGNTCNGARGTNGTNYTNTTYAARCCNAARGCNYTNATG AAYGTNAAYGGNGAYAAYGTNGCNAARACNGCNAARCARYTNGGNGTNAARGCNGAYMGN ATHTAYYTNGTNCAYGAYGARYTNGAYYTNCCNGTNGGNAARTAYAGYYTNAARATGGGN GGNAGYGCNAARGGNCAYMGNGGNGTNYTNTCNTGYATHTCNTCNYTNAARTCN------ ---------------AGYGGNYTNTGGCCNGAYGARTGYACNGAYACNGTNATHYTNCCN MGNYTNMGNATHGGNATHGGNMGNCCNGTNTCNAARTCNGARGTNGTNTCNTAYGTNYTN GAYCCNTTYCCNMGNGARGAYATGGARGCNGTNTCNGTNGCNATGGAYGCNGGNATHGAY YTNYTNYTNMGNCAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GAYGAYGAYYTNGAYGAYGAYGAY GAYGTNGARGARGGN------------GARGGNMGNCARCCNACNCCN---CARYTNCAR ATHAARGCNACNGTNTCNMGNCAYCAYYTNGAYMGNACNACNCCNGCNGTNGGNGGNGCN YTNYTNACNTGYCCNCCNTCNAARAGYAAYAARATGATHGTNACNTCNMGNTCNGGNGAY AGYTAYGTNACNGCNTCNGAYAAYACNGARGTNCCNGARCCNGTNGCNAARGTNGAYGTN GARAAYGTNAARACNMGNCCNATHYTNGGNCARCCNTCNTCNGAYTCNCAYGCNYTNMGN GAYGAYGARGCNTCNACNGAYMGNCCNYTNAAYACNMGNTAYATHCCNTCNCCNGTNATH GTNAGYTGYGAYGARGAYAARGARAAYGCNCCNAARAARAARGAYAGYAAYAARGCNCCN AARCCNAGYMGNYTNACNCCNGTNCARGARGGNGTNGGNAARACNTTYGTNAARCCNMGN TCNTAYYTNACNGTNGAYGAYATHMGNCARGGNAARGGNTCNGARGTNGAYGAYGAYGTN YTNTCNGTNTCNATGATGTCNGTNGCNTCNAGYTCNTCNYTNGCNTCNGARGTNYTNGAR MGNGCNMGNAARMGNCARAARGARTTYTGG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGNTCNGGN AARAARMGNTGGYTNCAYCCNTCNGARGCNYTNACNMGNGGNCAYATHYTNTAYACNGTN AARTTYYTNGGNGARTGYAARGTNGAYYTNCCNAARGGNACNGARGCNGTNAARTCNGCN ATHACNAARATGAARTTYAAYAARCAYATHAARMGNGCNGARGGNCARAARACNCCNAAR GTNGARYTNACNATHTCNGCNGAYGTNGTNCARATHYTNGAYYTNAARAAYAARACNGTN YTNCAYAARTAYCCNYTNCAYMGNATHTCNTAYTGYGCNGAYGAYATGTCNGAYAARMGN GTNTTYACNTTYATHGGNAARGCNCCNGAYAGYAAYGAYCAYTAYTGYTAYGTNTTYGAY AGYGAYAARTGYTCNGARGARATHACNYTNACNATHGGNCARGCNTTYGARYTNGCNTAY CARAARTTYATHACNACNTCNACNCCNGARGCNGARYTNAARAARMGNTTYYTNGCNCAR CARAARAARYTNAAYGCNYTNCAYTAYGARAAYCARGTNYTNAARAARMGNYTNMGNGAY YTNGARTCNYTNAARGGNGGNGCNGAYATGGARCARTAYAARATHCARCAYCARYTNAAR GAYATHACNACNGTNATGTTYGAYYTNMGNGARAGYTCNACNGAYGAYGAYGAYGARYTN TCNGGNCARACNGARACNAAYAAYAAYAGYAAYGTNGTNGGNMGNMGNYTNGARAAYYTN ATGYTNGTNGAY------------------GGNACNACNACNCAYGCNCAYACNAAYGGN AAYTAYCAYGGNAAYACNAGYTCNGGNACN---TCNGCNGCNCCNATHYTNAGYCCNCCN CCNCCNAAYTCNMGNCCNATHMGNCARCCNTCNAGYAAYCAYAAY--------------- ------GCNACNCARCAYACNAAYGGNAAYAGYAAYACNMGNATHGCNGCNCCNGGN--- AAYCARACNGAYGTNTTYGGNATGCCNGCNTTYGAYCCNGCN---CCNCCNTCNAARCAR GARYTNATGGAYATHCAYGAYGGNTTYAGYMGNGGNYTNTCNTTYGGNACNGAYAAYTTY AAYATHGARGAYYTNGAYCCNYTNAGYCAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARATGTCNTCNATHACNTGYYTNGCNTGYAAYGTNGCNTTYGARGAY TTYGARYTNGGNMGNACNCAYTAYAARACNGAYTGGCAYMGNTAYAAYYTNAARMGNAAR GTNGCNGGNYTNGTNCCNYTNACNYTNGARAARTTYGARGARMGN---------CARAAR GCNCARCARCAR---GARGARGCNGCNAGYMGNGARAAYYTNGTNTGYAARCCNTGYGGN AARTCNTTYAGYAGYCCNAAYGCNTAYGAYAAYCAYYTNCAYTCNAARAARCAYAARGAY GTNACNTCNGGNTCNGARAARAGYAARAARAARAARCARCCNCARGGNCAYMGNCCNCAR TCNGGNACNGCNMGNCAYYTNGARAARCCNGARCCNAARACNGAYGARGARATGCARGAY GARGARGAYGAYTCNGAYGCNGARTCNTGGGAYAGYTGYGAYGARGARGCNYTNGGNYTN GARGARTGYYTNTTYTGYTCNTTYATHAGYTCNTCNYTNGARGAYAAYYTNTCNCAYATG ACNTCNGARCAYAGYTTYTTYYTNCCNGAYGCNGAYTAYATHTGYGAYYTNGARGGNYTN YTNTCNTAYYTNGGNGARAARGTNGGNGCNGGNCAYATGTGYYTNTGGTGYAAYGARAAR GGNAARAGYTAYCARACNTCNAARGCNGTNCARAGYCAYATGYTNGAYAARGGNCAYTGY AARATHYTNCAYGARGCNCAYACNYTNTGGGARTTYGCNGAYTTYTAYGAYTAYACNAAR AGYTAYCCN------GAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CARGCNTGYYTNGAYYTNGCNGAYCAYCARMGN GAYYTNYTNCCNCARATHCAYCARGTNTGGCCNAGYGTNTCNYTNMGNTTYCAYAGYGAR GARAARTTYGTNGTNATHAARGCNYTNCARACNYTNGTNMGNATGGTNAGYGTNTCNGGN AAYTTYATGCARCARMGNGTNATGAARGAYGTNGTNCCNAARATHGGNAGYTTYATGGCN AARCARGCNGCNYTNAGYATGGAYAGYMGNTCNGCNTAYTCNAAYTCNACNAGYTTYAAR YTNCARYTNGCNGTNYTNGARACNYTNGGNCCNYTNGCNGCNGARYTNGARYTNGAYGGN AAYAAYYTNGAYGCNGTNGCNMGNATHTGYYTNCCNTAYYTNAAYGAYMGNCARCCNGCN AARYTNCARGARGTNTGYGTNGCNGCNTTYTCNCCNTTYATHGCNCARGAYGCNGAYGCN ATGTGGYTNYTNYTNTGYCARACNTAYTGYCCNTGYMGNTAYYTNACNCCNCAYCCNGCN TTYMGNCCNATG------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARYTNGCNYTNYTNATHCARMGN AAYCCNACNATGCCNGTNGAYGARGGNCCNYTNAGYCCNTCNAARAAYTTYAGYATHGAR CCNYTNGAYGTNGCNGCNCAYYTNAARYTNYTNGGNGARTCNYTNAGYATHATHGGNATG MGNYTNCARGARCAYAARGGNATGATHGCNGTNCARGGNAGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GCNCCNCCNCCNTAYGCN--- GTNGGNGAYCCNGCNTAYCCNCCN---CCNCCNGCNGGNTAYTAYGGNGCNCCNCCNCCN CARGCNTAYGGNGCN---------------CCNCCNCCNATGGGNTAYGGNGCNCCNCCN CCNCARGGNTAYGGNGCNCCNCCNCCNCARGGNTAYGGNGCNCCNCCNCCNCARGGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARAAYCCNCCNAAR---TCNACNAGYAARAAYGARGARTCNGTNGAY---TCNAARAGY TCNTCNCCNGGNATHTAYAARGCNYTNGTNCCNAGYAARAAYGGNCARCARAARAARGCN GGNAARGARGTNTCNMGNGTNAAYGGNAGYATGMGNGARATGTCNCCNYTNAAYTCNGCN AGYAARTCNAGYCCNAARGARGTNTCNMGNTAYAGYCCNAAYCCNGAYYTNGCNATHGCN ACNGTNCCNMGNAARYTNGGNGAYAARAARAGYGAYTTYYTNMGNGCNATHMGNAAYGAR AGYTCNGTNMGNAAYGGNGAYGCNTAYCAYAGYCARAAYGAYGAYYTNGAYAARAARGAY TCNATHGAYGARAGYGARGARGARAARCCNCAYATG---------AAYGGNGAYMGNGAR GTNGAYAGYAAYGARAAYYTNYTN---------------AAYGTNAARAGYGCNGARAGY TGYGARACNTTYTCNAGYGAYCAYGGNGTNAAYGGNGAY---------TCNYTNATHAAY CAYGTNGAYCAYATHACNYTNTCNGGNGARGARGARGARMGNMGNYTNYTNYTNTCNATG GGNTGGGTNGARGARGAYAAYACNGARTAYGTNATHACNGARGAYGARATHAARGARTTY CARAAYYTNGTNCARAAYTAYTGYCAYGGNCARAARAAYGGNTTYAARTCNACNYTNMGN AGYGCNYTNGAYMGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYGGNMGNTAYCCNMGNGARTAYAAYCCNAARGTNCAYGGN CCNTAYATGCCNGGNMGNTTYTAYGGNAARCCNGAYACNCCNTTYGGNGARGTNAARYTN GGNGARYTNGGNTCNTGGTTYGGNMGNMGNAAYAARAGYCCNCARGGNATHTGGAGYTGY ATGCAYMGNGCNTAYTGGMGNTGGGCNGCNAAYAAYYTNCAYGTNMGNCARGCNGGNTTY GTNCCNATHGGNCARGCNGCNATGGTNYTNTCNATHACNTTYTTYGCNYTNYTNTAYAAR GARMGNAGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARAARGAYGGNCARYTNMGNYTNGCNGARATG AAYYTNCARACNGCNCARAARCARGCNAARCAYCAYGCNCARGARATHGGNMGNTAYGAR GAYACNYTNGCNCARYTNCARACNGAYCARGARAARYTNCARGARCARTAYMGNCARTCN AGYTCNAAYYTNATGGARGCNGAYACNAARGTNCAYGAYYTNAARGTNCARYTNACNACN YTNCARGGNCAYCAYAARGARGGNATGGAYCARYTNACNGARAARTCNMGNCARYTNGCN GCNYTNAARACNGARGCNGCNAARATGGCNCARCARAAYAAYACNATGAARGARGARATH ATGYTNTAYGAYGAYAARGTNMGNAARYTNCARCARGARYTNMGNAARTCNCARGARYTN AAYAARGCNACNGAYGARGARYTNAARCAYTTYGARGARMGNTAYACNAGYYTNCARGTN GAYYTNGTNTCNAGYCARGARAARCARAARCAYTCNYTNCARGARYTNTCNTCNAGYGAR GARGARATGGTNGTNATHAARGTNGARYTNAGYTCNYTNCARGARAARTAYAARGCNGTN AGYGAYGAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGAAYTAYYTNYTNAAYAARGCNGAYGARGAYGARGARGTNGTNAAR GTNGTNTCNATHYTNCAYAGYATHGARACNYTNAAYTCNACNGARATHGCNCARGCNGAY GTNGCNCARTCNYTNATHAARGCNCAYGGNYTNYTNGARMGNCARATHCCNACNMGNTTY TTYMGNATHMGNGARACNTTYGARGCNATGGTNGAYCAYGCNCCNYTNGARTGGYTNATH MGNAARGTNCCNAARATGGCNGARYTNGGNYTNYTNGAYCARCARTCNCCNGTNGGNGAY ACNGTNATHGCNMGNYTNAARGAYGCNGARGCNTTYCARAARGARAARGTNTCNCCNGCN ACNGTNTTYTCNATHGTNMGNAARTAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GTNGTNATGATH AGYCARTGGTGYATHCARYTNAARYTNAARYTNGCNACNGTNTAYAARCARGTNATHCCN GGNTCNAARGAYGTNATHTGYCARGTNTAYGTNGCNGARMGNYTNYTNGCNACNTGYAAR GGNCCNGGNMGNTGGGARGCNCARAGYAARGCNTTYACNCARGCNMGNAAYGCNYTNYTN GGNGCNACNGGNCAYGCNYTNYTNGARCARYTNCCNTGYYTNGAYYTNGAYGAYGTNAAY GGNACNGAYGTNYTNGAYGTNGTNTAYAARGGNTAYACNAARTTYACNGARTCNAAYMGN TAYCAYYTNTAYMGNTCNAARAARYTNCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATHYTNTTYCCNCAYTTYTCNACNAAY TAYAGYAARAARGARYTNGARTGGGAYGARATGAAYATHYTNGCNACNCAYCAYCCNCCN GAYAARGAYTAYGGNTTYATGAARGTNGAYGARCCNCCNACNCCNTAYAAYMGNGCNGCN ATHTCNGAYGGNGARGAYGARGAYGGN---YTNGARAARAARGGNAGYATHGARGGNYTN AARGGNGTNGAYCCNTCNGAYYTNGCNTCNMGNYTNAGYACNAGYGTNGAYGCNGGNGCN AGYMGNTTYGARGCNGAYGARGAYGAYGAYGAYGARGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GAYATHTCNGAY ACNGTNGCNCARMGNMGNMGNMGNGTNGGNGTNAGYMGNTGYAGYAGYCARCCNCCNCCN GARMGNMGNAGYACNATHAGY------AGYCCNATGGCNAAYAGYATGCARACNMGNATG MGNAAYYTNTCNGGNGGNAGYAGYGGNAGYACNGCNAGYGGNAGYAGYTGYGGNAGYTCN ACNCARYTNGAYAAYCARTTYTCN------GAYAAYCAY------TTYTTYTCNYTNGAY ATHCCNCCNTTYTCNACNCAR---TCNGTNAAYGCNAAYGTNMGNGCNGARTCNTCNTCN CCNCCNTGYMGNAARYTNGAYMGNAGYYTNAGYGAYGGNGGNAGY---------ACNGGN TCNGGNTCNTCNCARCAYMGNTTYYTNAAYGCNAGYMGNTAYAARACNGARYTNTGYMGN CCNTTYGARGARAGYGGNTCNTGYAARTAYGGNGAYAARTGYCARTTYGCNCAYGGNATG CAYGARYTNMGNAAYYTNGAYMGNCAYCCNAARTAYAARACNGARYTNTGYMGNACNTTY CAYACNATHGGNTTYTGYCCNTAYGGNCCNMGNTGYCAYTTYGTNCAYGARGARGAR--- ------AARCARGARGGNTCNTCNAAR--------------------------------- ------GTNAAYAGYGGNAGYAGYAGYCCNTCNYTNAGYCCNACNGGNAGYGAYATGGAY ------ACNTTYTCNTAY---------------------------------AAYTCNAAY AARCAYAAYACNAAYACNYTNACNGTNAAYATHAAY------------AAYAAYATHGGN ACNTGGGARTCNYTNGAR---CAR---MGNTTYAAYTCNATHAAYYTNAAYMGNGAYTCN MGNGAYTCNTTYTCNTCNTCNAAR------------------------------------ ---------CCNACNGARGARAAYGAYATHTTYAGYTCNATHTCNGTNTTYAAYCCNAAY GARGTN---GTNGAYAAYGCNCCN------CCNTCNTCNAAYGCNTAYTCNTAYTCNAAR CAR------CARYTNGAYAAYTTYCCNGCNCAYGTNGAYACNTCNTGYTAYTGGCCNACN ---------------------AGY---MGNCAYGTNGAYCCNTTYCAYATHTCNCCNACN GGNTCNACNGGNTCN------------------------ACNAGYTCNGGNAGYGAYTGY AGYGGNAGYACNGARAGYYTNCCNACNTAYGGNGTNAARGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CAYGGNTAYCAYMGNGCNGAYGCNAARGAYTAYTGYGAY ACNGAYTAYGARATGGGNYTNYTNGCNCARCCNGARAAYTAYCCNTTYTGYCARGARTCN TTYTGYGARACNTTYACNATGACNAAYGTNGTNCCNGARGTNCCNGGNTTYAGYTGYGGN CCNTGGTTYGAYYTNGARTGYTAYATHMGNGARAARYTNGTNCARAGYAAYAARAGYGTN TAYGTNTGYTCNGGNCCNYTNTTYYTNCCNGTNGARGAYGGNAARAARACNGTNAARACN TTYGAYGTNYTNGGNGAYGGNGARGTNTCNGTNCCNACNCAYTTYTTYAARGTNATHGTN ATHGARACNCAYGAYGGNCARYTNGARYTNGARTCNTAYATGYTNCCNAAYTGYACNCCN GARTCNGAYGGNGAYGCNAAYYTNGAYGARYTNYTNACNCCNYTNTGYCARATHGARCAY CAYTCNGGNYTNATHTTYTTYCCNGAYAARAAR---TGYTTYAGYAGYAAYAAYAARMGN MGNGGNGCNAARYTNCAYGCNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------MGNGGNTTYACNAAYMGNGTNMGNGCNGGNATHGCNACNTTY TGGGCNAAYCCNGARGAY---MGNAAYTAYMGNGARGTNGARAARGGNAARATHGTNGTN TAYGCNACNTCNATGAGYGTNGTNMGNGARACNAGYGARMGNTGYAARGTNGTNMGNGCN ATHYTNCARAAYCAYATGGTNMGNTAYGARGARMGNGAYYTNTAYATGAGYMGNGARATH CARTGYGARYTNAARCAYMGNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNTCNGGNYTNGGNGTN YTNMGNGGNGAYTCNTTYGARCARATHCARGAYAARGTNAARCARGAYTTYTTYCCNATH YTNATGAAYAAYTAYAARYTNTGGCCNGCNGCNCARYTNATHAAYTTYTCNYTNGTNCCN YTNCARCAYMGNGTNYTNTAYGTNAAYTTYGTNTCNYTNTTYTGGAAYGTNTAYYTNGCN TGGGTN------------ATHYTNMGNAAYYTNACNGARGARYTNTTYCCNTGGYTNTAY AAYAARGARYTNYTNAARAAYAGYGTNCAYMGNTTYTGYACNAGYYTNAARACNGARCCN TGYTCNACNYTNTTYTAYYTNYTNYTNGTNATHTTYGGNTTYGTNCCNTTYATHTGYTTY TTYYTNTTYATHGGNGGNACNTTYATHYTNACNATHGTNTGGTTYGCNGTNTGYCARGCN GTNGTNGTNACNGTNTCNGCNYTNATGTTYGGNGGNTTYATGGTNTTYYTNATHGCNATG TGYTGYTCNATHGCNGGNGTNTTYGGNYTNATHATHCAYGCNGTNTAYGGNTGG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARCARAARATHGTN CARGARCARGARYTN------------------------ATHTTYYTNGAYGTNTTYMGN MGNGCNGAYAARAAYGAYGAYGGNTTYATHTCNTGGGARNNNTTYGTNTCNTTYTTYGCN GAYGGNGTNATGGGNAARGARGARYTNCARGCNYTNTTYAAYGARATHGAYTCNCAYAAY ACNAAYAAYATHGAYACNGGNGARYTNTGYTCNTAYTTYTCNCARCAYYTNGGNGAYTTY AARGARGTNTTYGGNYTNATGGARGARATGAAYAARAARYTNACNAAYGTNYTNTTYGGN ACNGCNAARGTNTAYCARGAYTCNTCNMGNACNGAYAARTTYGTNACNMGNTTYYTNATG MGNGARATHYTNAAYCARACNYTNGCNYTNCARMGNCCNYTNGARTCNGCNGCNGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AAYATHTAYYTNGAYCCNAGYACNCAYGARATHCAYYTNTTYGAYYTNGAR GAYGGNTGYAGYTAYACNGTNTTYYTNTCNTGYGAYMGNATGAARCARACNAAYGAYGTN ACNTTYACNGGNGARAGYYTNTGYGAYGAYCAYGAYCCNGGNGAYAARTCNATHYTNTCN AGYACNGAYGGNCAYYTNGAYGAYCCNGTNYTNGCNCCN------AARTCNGTNAGYTTY GAYYTNATHGGNTGGYTNAGYGCNGTNYTNTTYCCNGTNGCNGGNYTNGTNYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYATHMGNGCNAGYMGNTCNTAYGARATGGTNGAYMGNGTN GTNAGYAAYMGNTCNCARCCNGAYATHMGNYTNTGYGCNTCNAGYCCNGGNATHTGYAAY GTNCCNTCNCAYGGNTCNAGYCCNGCNMGNTCNTCNAAYACNAGYTGYAGYGAYCAYCAR GCNGCNYTNYTNACNTCNAARGCNGAYTGYATHYTNGAYATHGTNAGYGARGARAAYMGN TCNYTNMGNAARGARYTNGCNGCNGCNACNGTNAARGTNTCNAARYTNYTNAARTTYGAR GTNGARGTNGARAARATGCAYATGGCNCAYGARGCNYTNYTNCARTCNCAYCARAARMGN GARGCNYTNTGGATGGCNATGAARMGNAARYTNGARGARMGNGTNMGNAAYYTNGARGGN AARGGNGGNGGNGCNYTNGCNGAY---GGNCARGCNCARATGGGNGARTCNYTNACNGAR YTNGARTGGMGNAAYAARATGGCNGARAARGAYTCNYTNATHAGYMGNYTNGTNGCNCAR AAYCARGARYTNGCNTCNAGYTGYAARCARGCNGARGCNGARAAYGTNCARYTNAGYGTN AGYYTNGCNGARCARAARGCNCAYTCNGARATHGTNGARAARGCNYTNGTNAAYACNCAR GCNMGNGTNATHATGATGGAYGGNGAR------------------TAYCARAAYMGNGAY TCNAAYMGNCARACNGCNGAYGGNAGYYTNAGYCCNTCNTCN------------------ ------------------------------------------GCNAGYTCNATGMGNATG ACNGARTGYGTNGCNMGNCARGAYAARACNTCNYTNGCNGGNGAYMGNMGNGTNGARGAY ---------------------------------ACNGAYATGAARCARAARTGYGTNACN GAR---ACNGARMGNGAYYTNMGNYTNGAYGAYACNTCNAARTCNATGCARCARGTNAAR YTNGCNGCNTTYGARAARAGYTCNTCNGAYATHGARAARYTNATHGAYGARGCNAARACN GAYAARYTNAARCAYATHGARGARATGCAYGARGGNAAYAARAARATGGCNGARATGGAR GCNAARGTNAARAARYTNCARACNCARATHGTNGARAARGARGCNATGYTNAARTTYTTY CAYMGNTCNAGYMGNGCNYTNCCNMGNAGYTCNAGYATGCAYGCNYTNTGYCAYTCNCCN MGNCAYTCNCCNCARCCNTCNATHGTNACNTCNACNCCNCCNGARGGNTCNTCNTCNACN ACNACNTTYATHGGNTGYGGNGGNCAYMGNGARGGNTCNTCNGTNCAYCAYAARAARACN GGNAGYACNAGYGCNGTNGAYYTNGGNMGNAARYTNTCNYTNGGNGARGAYATHYTNGCN AARGTNCARAGYYTNAAYYTNGARGGNGARGAYGAYGAYCARGAYGCNGTNAARYTNTGG CAYGTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYTTYGARTCNTCNMGN ATHGGNACNCARGARCAYTGGGAYGAYACNTAYCARGARGARYTNMGNAAYTTYGARGAR ATHGGNGAYGTNGGNGARATHTGGTTYGGNGARGAYGCNCARGAYMGNATGGTNMGNTGG ATHTGYAARAARTCNGGNYTNCCNCAYACNGCNMGNATGATHGAYYTNGGNTGYGGNAAY GGNATGYTNGTNYTNTCNYTNMGNAARGARGGNTAYTCNAAYYTNATHGGNGTNGAYTAY TCNAARTAYTCNGTNCARYTNGCNGARAARATHTCNGCNTCNGARGGNATHACNGAYGTN ACNTTYGARGARTCNGAYATHYTN------TCNGARGCNGARGCNAGYAARMGNGCNGGN YTNTAYGAYGTNTGYYTNGAYAARGGNACNTAYGAYGCNATHAGYYTNAARAAYACNAAR GAYGCNACNGAYMGNATGYTNTAYATHTCNCAYGTNCAYTCNATGYTNMGNCCNAARGGN GTNYTNGTNYTNACNTCNTGYAAYTGGACNAARGCNGARYTNGARCARCAYTTYTCNAAR CAYTTYGAYATHACNGAYGARATHCCNTCNCCNAARTTYACNTTYGGNGGNCARACNGGN CARAARGTNACNTCNYTNATHTTYACNMGNAARGCNCARATHATHGTNTTYCCNGARAAY GGNATHCAYGGNYTNGGNAAY---AGYMGNGAYYTNATHTTYCCNTAYYTNGARCCNATH CCNGAYGCNGAYAARCCNAARTGGAAYCCNTGYGAYGAYCCNCARMGNGTNGGNGCNACN GARGTNYTNMGNGARYTNAGYTGYATHGCNAARTCNGCNAGYYTNTAYYTNGTNGCNAAY ATGGGNGAYMGNGTNACNTGYGAYCCNAAYYTNAAYCCNAARTGYCCNMGNGAYGGNMGN TTYCARTAYAAYACNGAYGTNGCNTTYGAYCCNGAYGGNAAYYTNYTNGCNAARTAYCAY AARMGNAAYYTNTAYTAYGARTAYCARTTYGAYACNCCNGAYTCNAARGTNGTNTAYTTY GAYACNCCNTTYGCNMGNGTNGGNATGYTNATHTGYTTYGAYYTNYTNTTYGARAAYCCN GCNGTNCCNATGGTNMGNGAYCAYGGNGTNACNYTNATHGCNTTYCCNACNGCNTGGATG GAYTCNYTNCCNATHYTNTCNGCNACNGGNTAYCAYTCNTCNGTNGCNMGNGGNYTNGCN GTNAAYTTYYTNTCNGCNAAYYTNCAYATHCCNGARTAYMGNTTYACNGGNACNGGNATH TAYACNCCNCARGGNATGGCNGAYTTYTAYTAYAAYAAYACNGCNTCNGCNAGYGGNAAR YTNYTNGTNGCNGAYYTNGAYGTNATH---------------------CARTCNAAYATH MGNCAYGAY--------------------------------------------------- ------------------------------------------------TTYGARAGYMGN TCNMGNGAYAGYTTY------------ACNACNAAYACNAGYGAYACNTTYGGNTCNATH YTNTAYAARGGNAAYTAYACNTTYMGNCARYTNAARAARYTNTCNGAYACNYTNGAYGTN TGYAAYAARAAYGTNTGYTGYTCNYTNAAYTAYACNATGTCNCCNGGNTCNAAYGAYAGY GARATGTAYGCNTTYGGNGCNTGGGAYGGNGCN------AGYGGNGGNCARTAYTAYTTY CARACNTGYGCNYTNGTNAARTGYGCNAAYAGYTCN---GAYAARAGYACNTGYGGNYTN TAYACNTTYGAYGCNAAYATHMGNTTYGAYTAYGTNTCNGTNTCNGGNMGNTTYGAYACN GGNTAYGTNTAYCCNCARGTNGTNYTNGCNGAYGGNGGNCARYTNGCNATGGCNGAYAGY ACNTCNTGGACNTTYCARGAYGGNMGNYTNGARACNTCNGGNTCNGGNYTNCARYTNCCN YTNYTNTCNGCNACNYTNYTNGCNMGNCCNTAYGAYAARGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY GARGARGTNMGNTGYCARTTYATHGCNGCNTTYMGNAAYGAYGAYTTYCAYAARAGYGTN CARGAYYTNATGCCNAARAGYTCNTGGTCNYTNACNGAYGCNGTNTCNAAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CCNYTNMGNYTNGGNAARGGNGGNGGNCCNGGN ATHGGNGAR---------ACNAGYTCNCCNCCNAARMGNGCNMGN------GTNGGNYTN ------ACNGCNAGYAAYCCNATHGTNGARGCNGTNGAYAAYTCNAARTTYYTNAGYCCN YTNCARGGNTAYMGNGTNATHGTNACNAAYYTNTTYGCNMGNGTNACNCARGARGAYATH ATHGARYTNTTYAGYGTNGTNGGNCCNYTNAARAARGCNAARYTNYTNAARGARGGNTCN GCNGARGTNGTNTAYACNACNAARGARGAYGCNGTNAARGCNGTNAAYAARTAYCAYGGN MGNGARYTNGAYGGNCARCCNATGTAYGTNAARATGACNACNCCNGTNGCNGCNTCNGTN ---AARATGCCNCAYGARMGNGAYCCNGAYATHACNGGNGARGCNYTNAARYTNTAY--- ------------------------------------------------------------ ------------------------------------------------------------ ---TTYACNCARMGNTTYGTNMGNYTNATHMGNGARTGYGTNYTNACNCAYGARTGGAAR AAYGTNYTNAARYTNGTNAAYTGYATHGTNTCNGARGGNYTNGARGTNGGNGARACNYTN TGGAARAGYGGNATHATGTCNATGGTNYTNACNAARAARCCNAARYTNYTNGGNCARTTY GTNMGNCARYTNTAYGGNYTNMGNAAYATHTCNTGYGTNGARGTNYTNYTNGAYTAYYTN YTNCAYYTNYTNATHGARGAYGAYMGNGARGARGCNAARAGYYTNGTNGGNAGYTAYMGN CARTAYACNATHTTYGCNGARGCNAARACNACNGARMGNGCNACNGCNAARGTNYTNTTY CAYGCNTAYATGGGNYTNGTNCAYTAYGTNGAYTGGAARGARGCNATHAGYAARAAYAAY GARYTNGARGARCARACNGAYYTNTCNAGYAARATHTCNATHCARGTNAAYGARGTNACN ATGAARMGNTCN---GCNGAYGARGCNATHAGYYTNTTYTCNTGGATHCARGAYGARCCN GGNGTNTGGGAYATHTTYATHGTNAARATHGTNGARATHCAYGARTAYTAYCAR------ GARGARGCNAARAAYGTNYTNACNAARTAYMGNAGYAARAAYCCNGARAAYCCNAAYGCN CAYMGNTAYYTNTAYGAYTTYYTNYTNAARTAYGGNGGNACNAARGARGARCARATHGAY TGYYTNAARAGYTTYGTNCARYTNGAYCCNAGYAGYTGYYTNGCNATHGARYTNTTYCAY YTNCARGAY---------AAYCCNAARTTYCAYYTNYTNTTYGAYTAYYTNGAYTTYGAY CAYCAYMGNGARGAYYTNGAYTCNTGGAARYTNYTNAARTGYCARYTNAAYGCNGTN--- ---ACNMGNGAYYTNAARAARGARGTNATGGARTGYTGGGARGTNMGNAARGAYTGGTGG CCNMGNCCNYTNGTNGTNATGTGYTCNYTNGCNTGYAGYATHTTYACNTGYYTNGAYGGN ---AARMGNACNCCNGAYTGYTCNACNTGYAARGARATHGTNGAYAAYTTYCAYAARTCN GTNTCNAARACNGARAARTCNAAYTAYGGNGGNGGNAAYTCNCAYTGGGARGARAAYTCN YTNAARTCNTAYGCNATHAGYGARGTNMGNYTNGTNGARATHATGGARCARYTNTGYCAR GGNAARTCNTCNGARTGYCAYTCNATGYTNGARGARCAYGARGARGTNATHGARCAYTTY TGGCAYCARCAYTTYGCNYTNAARACNAAYAARGAYTTYCAYTCNTTYTTYTGYGTNGAR AAYGTNAARGCNTGYTGYCCNGAYAAYACNTAYGGNAARGAYTGYAAYCCNTGYCCNGGN GGNGTNACNMGNCCNTGYYTNGGNCAYGGNGAYTGYGAYGGNGCNAGYACNMGNACNGGN ACNGGNMGNTGYMGNTGYCAYTCNGGNTAYACNGGNGARYTNTGYGAYAARTGYAARGAR GGNTTYTAYCARCAYAGYCARAAYGARACNGAYATHGARTGYAARGTNTGYCAYATHGCN TGYCARGGNGGNTGYTCNGGNGGNGAYGCNAARAGYTGYGCNAARTGYAARGAYGGNTGG YTNACNCAYGCNGARGARGGNTGYCARGAYATHGAYGARTGYCARGARGARCCNTGYGAR GAYAGYCARTAYTGYACNAAYACNCARGGNTCNTAYTCNTGYYTNGAYTGYGAYGTNGCN TGYGTNTCNTGYACNGGNTCNGGNCCNTGGAARTGYAAYMGNTGYAARGAYGGNTAYGAY AARYTNTCNGAYGGNAAR---TGYGARGAYAARGAYGARTGYCARTCNGAYGCNAGYCCN TGYYTNAARGAYAARGARGARTGYGTNAAYACNCCNGGNAGYTTYCARTGYATHTGYGGN CCNGGNTTY---GAR------------------TAYAAYAARGAYAARGARTGYGTNAAR ACNTCNAARNNNACNGARGARATHAARATGACNGARAGYYTNAARAARATGGGNGCNTCN GARAGYAARMGNMGNGTNGTNGTNGARGAYGTNAAYGGNGARGGNGTNGTNCAYGTNACN GARGCNATGCCNGAYTCNCCNCARCARGGNTCNMGNTCNCCNACNAAYAGYCCNCARACN GCNAARAARCCNGCNCARCCNYTNCAYCAY------CARCAYCARGCNTCNMGNGAYAGY MGNCARTTYCARGCNATGAGYAARGARATHGARGAYTTYTAYAAYCARAARYTNGAYGAY YTNCARCARMGNAGYGARGCNYTNCARCARCAYTCNAAYGARCARTTYGCNAAYGCNGTN AARGARGTNGARCARAARTTYATGAARTAYACNGCNTCNCCNGTNTGYCARGAYYTNCAR ACNAARGTNYTNCARTGYTAYCARGCNAAYCCNAAYTCNGTNYTNAAYTGYTCNCCNGTN ATHAAYGCNTTYTCNYTNTGYGTNGAYMGNGCNMGNYTNTCNGTNTCNATGACNATGGAR ACNCCNCARACNATHGCNGCNAARGARGTNGARMGNTGYTCNAARGTNGGNATGCARMGN YTNCARGARGGNTTYCCNGAYAARGCNYTNACNGCNTTYMGNAGYGCNTAYATGAAYGCN CARTCNYTNAGYCARCAYGGNTAYATGGTNMGNGCNTGYGCNTTYAAYYTNGGNGCNATG YTNATHTCNACNAAYAGYTTYGTNGARGGNATHGCNTAYYTNAAYAARGCNATHCCNCCN GAYGGNAARMGNGAYGGNMGNTCNAAYGGNGAYYTNTAYTAYAAYTAYGGNYTNGCNTAY GARGGNYTNAARAAYGTNTCNAARGCNAARCARTCNTTYGARTTYGCNYTNAARGAYTAY MGNACNGARGGNCAYAAYGTNAARATGGARGCNGAYACNATHAGYCAYYTNAGYMGNYTN TGYYTNGARAAYAAYYTNYTNTCNGARGCNGAYAAYTGGATGAARCARYTNCCNYTNYTN TAYTCNAAYYTNGGNGARTCNCARAARGARYTNCARTCNAARGTNGAYMGNTCNAAYYTN YTNYTNAARATGGAYCARGCNCARGARGCNCARGCNGTNGCNGAYGARTGYTTYCARAAY YTNGARTCNACNCCNCCNGAYATGTCNGAYGCNAARATGTAYAGYGAYYTNTGYGTNGCN TAYACNCARATHATGYTNTAYGAYAARGCNATHCARTGYAGYGARAARGCNYTNCCNYTN GTNGARGARCCNAAYGGNGAYCCNMGNYTNGCNGCNGTNYTNTAYCARAAYYTNGGNGCN ATHTAYAAYTAYATGAGYCARTTYGAYAAYGCNYTNAARTAYCAYCARAARGCNTGYAAY ACNTAYGCNAARYTNCARATGMGNACNAAYCARGGNCAYTGYTTYACNAAYATGGGNTAY GCNTAYAGYCARYTNAARGARATGGAYAARGCNGGNGARTGYTTYYTNCAYGGNYTNCAR GCNGCNMGNGAYTGYGGNGAYYTNMGNACNGARTGGCARAAYYTNGARGCNYTNGCNAGY GTNGCNTAYCAYAARMGNTCNYTNMGNAARGCNGARCARTAYTAYCARCARGCNGTNTCN GTNYTNGCNMGNACNCCNGARGGNGGNGAYCCNGTNGTNCAYAARMGNYTNATHACNAAR YTNAARCAYGTNATHCARAGYCARGTNTCNMGNCCNCCN---------------TCNACN CCNGCNAARGARACNATGACNATGGTNCAYMGNGCNAGYYTNCAYMGNGAYAGYGTNAAY TAYAARYTNGARTCNYTNGCNACNGARATGGARTCNGGNAAYATHAARGTNATHMGNAAR GGNAGYCARGTNMGNTAYYTNAARGTNMGNMGNTCNGGNACNYTNMGNCARTTYAARAAR ATHGCNYTNGGNYTNGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GCNTGYGCNGGNACNACNGCNGCNGARYTNATHAAYGGNGTNGARMGNYTNACNGGN GGNGTNATGGGNGGNMGNTTYTTYCAYTTYTGGCCNCCNMGNAARGTNAARYTNYTNCAY TGGYTNGCNTAYTGGGTNMGNMGNGGNGCNATHCCNATGGCNACNYTNAAYYTNCARCAR GGNCCNCAYTCNGTNTGGGARGTNCCNGAYTCNTGGCAYCAYCARATGGTNTAYGGNGTN AGYCAYCARGGNYTNTAYYTNACNAAYCCNYTNGARATHGTNTCNGARMGNTCNGCNGTN AARCARYTNCARAGYGAYTCNGTNYTNYTNGTNMGNMGNCARGAYATHATHTCNMGNTTY MGNGARTCNACNGAYYTNGGNCARYTNYTNGAYCAYCCNGAYCCNMGNTGGATGTCNATG AAYGTNYTNGGNCARGTNGTNAAYGTNYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYGGNACNGAYACNGARATGGARAGYGTNGTN GTNCAYACNAARGARGARYTNAAYAGYATGGAYCARTAYYTNACNAAYATGATGTTYATG TCNGTNAARAAYCAYMGNGGNGCNMGNCARGARATGAARTAYAARGTNCAYGTNTCNMGN YTNGARGTNTCNGAYYTNTGYCARCCNACNYTNYTNCAYYTNATHCARYTNCAYCCNACN ATHACNYTNATHTTYCARCAYCARGCNGTNAARATHAARAARAARAARGGNTAYGCNGAR GCNTCNTTYTCNACNATGACNGARYTNAARGARTTYGTNTAYCARYTNACNCARYTNAAR YTNTTYGARMGNMGNYTNGARGTNAARATHACNGCNTCNMGNCARACNGARCCNCCNGAY GTNYTNTCNTTYGTNATHCAYYTNAAYMGNAAYTCNAARYTNYTNCARYTNATHGAYAGY GGNGARGAYCCNAARATHAAYATHCCNYTNCCNTCNGAYAARGCNAARACNGAYTTYGAR ------AARGTNCCNTCNTCNGTNAGYCCNGCNYTNYTNCAYAGYYTNTTYCCNTTYAAY AAYAAYATHTCNGTNTCNAARAGYACNATHCCNTCNAAYCCNACNCCNGARYTNAARGGN CCNYTNTCNGTNTTYTTYGTNAGYCARCARTGGMGNGAYGCNGTNYTNGARTGYTGYTCN GAYTTYTCNGTNAAYGARTTYCCNYTN---------------------AARGARCARCAY MGNGTNTCNGGNAARMGNAARAARGGNACNCARGGNGAYGAYTCN--------------- ---------------------------------------------AGYCCNGCNGTNGAY GAYYTNGTNGCNAGYATGACNMGNGAYGTNTGYTCNGAYATGYTNCARTCNATHGARAAR YTNAARGARYTNGARTCNGAYAAYCCNAAYYTNAARMGNATHYTNGAYATGCARGARAAR YTNAAYACNYTNCARGARTCNYTNTCNTCNGAYGCNATGCARGCNGTNYTNTCNGAYCAR GAY--------------------------------------------------------- ---------------------CARAARCARAARGARATHGARATG--------------- ATGYTNGARGARGCNGAYAARMGNGARMGNGARAARGARGCNGARATGAARCARAARMGN GARGCNAAR---------MGNYTNGARGARGARGCNAARMGNAARTCNCARMGNACNMGN AGYYTNYTNAAYGAYTGGAARCARGGN------------GCNGTNATHGCNGAYAARYTN AGYCCNGARGCNGARMGNATHYTNAARCARMGNGARCARMGNATHMGNGARGARGARCAR AARAARMGNMGNGARGARGARYTNYTNAARMGNCARGARAARGARCARYTNATHGCNAAR MGNGARTAYGARAARCARMGNYTNATHCARGARATHGARGARGCN---MGNCARMGNGAY YTNCARAARGCNGARAARCARTCNAGYACNTCNGAYGGNGARTCNTCNTCNMGNMGNTAY TCNTCNACNGCNGGNGGNGGNGGNGGNAARMGNGGNMGNMGNTCNGARGAYGAYGGNYTN GARGAYMGNYTNTCNCARCARGGNAARATHGARMGNCARGARTCNAGYTAYMGNAAYCAR MGNGARAARYTNTCNAAYGCNCARMGNATHTCNGARGARCARTAYCAYTTYYTNMGNAGY TCNAAYCAYACNYTNCCNGCNGAYTAYGARATHACNYTNACNMGNYTNACNGAYMGNACN TGYCCNGTNCARGCNTGYCCNGCNAARACNTGYTTYAARACNMGNGAYAAYTTYATGGAY CAYTGGTCNATHTTYCAYCARGCNGARAGYACNATGMGNTTYTGYCARCARTGYTCNGCN TAYTTYATGGAYAGYMGNGARYTNGARCAYCAYATHATGAARCARCAYMGNATHCCN--- YTNAARGAYGCNGCNMGNYTNGCNMGNAAYGCNMGNGTNAARGTNATHGAYAAYCCNAGY TAYMGNAAYCCNGCNCCNTAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNCAYTCNYTNTCNGCNGTNYTNMGN YTNGAYGARCAYGARGCNGCNAGYATGCARGCNGGNGARTGYYTNGTNTCNYTNAGYGGN YTNGARGCNMGNGTNACNGAYMGNYTNCAYTTYTAYAARGCNCARTCNGTNACNGARMGN YTNMGNAGYYTNGAYTAYAGYACNYTNMGNGARGCNGGNATHGCNTGYCAYCARATGMGN ACNTGYYTNGAYCARATHTCNAARATHATHTCNCAYGCNTGGATHACNGARYTNCCNCCN YTNGAYACNCAYGGNMGNTTYTAYGAYCCNGAYYTNGCNAARGARACNGARAARYTNAAR AGYGARYTNACNGAYYTNCARACNAARTAYACNGCNYTNGAYAARACNGTNMGNGAYCAR CARGGNAARYTNTCNGCNTCNAARCARMGNCARMGNCAYTGGGARGAYTCNGTNTGYMGN CAR---------AARGGNAARMGNTCNMGNAGYTTYTCNGARTCNTTYGARGAYTTYAAY AAYATHGGNGARAAR---------------GAYGTNACNMGNGARACNGTNGAY------ ------MGNYTNGGNGAYAAYGARAARYTNATGCAYMGNAAYAAYAGYAARATGYTNGAY CCNGAYAARAARAGYGARTAYGARCARATHAARMGNTCNTAYGCNGAYATHYTNTAYAAR TGGGGNYTNYTNAAYCARMGNGTNCARGTNYTNAARCAYACNGTNTCNGTN---CARYTN GAYAARAARATHGARTTYTCNATHCCNTGYTCNAAYTGYAAYGAYAAYGTNTTYAAYGTN CARTGYAAYMGNTGYCARTAYCCNTCNYTNAAYTGYTCNATHTGYCAYATHGGNGTNAAR GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GCNAAYTTYGAYAGYYTNGARGGNCARYTNGCNAAR TGYTGYGARGCNYTNACNAARTGYGARAAYGARMGNAARGARYTNGARAARAARYTNCAR TAYGCNGTNMGNGARATGGARAARYTNGCNAARGARGTNAARGARYTNACNTGYGARYTN CARGARTGYMGNAARGARATHTGYGAYAARAAYGGNYTNATHGARGAYYTNGARCARACN YTNGARCAYGCNAARCAYGAYACNGAYTCNMGNATGTGYMGNGTNGAYCARCARYTNCAR AARTAYGARAARGARATHCAYGAYAARGGNAAYATGYTNGCNGARTGYGARGARAARTGY TGYMGNYTNCAYTCNTGYYTNAGYGARAARAAYTCNGARATHGARAARYTNGCNCARCAR YTNACNMGNGCNCAYTGYGAYYTNGARAAYYTNAARTGYCAYTAYGGNGARYTNCARGAY GARAARCARGCNYTNGTNAARTCNAAYAAYGARGARAARATHMGNAAYGCNGARYTNTGY CARGARAAYAAYCARAGYMGNGARCARYTNCARGCNGCNYTNTGYGAYGTNAGYACNTAY AARMGNGAYYTNTGYAAYTGYCARMGNGAYACNGARAARAAYATHMGNGARYTNGCNGAY YTNMGNCAYTGYYTNGARGAYAARGAYTGYCARYTNAARCAYYTNTCNGARGARAARTCN TGYYTNGGNAGYAARYTNGCNGCNACNCARTGYMGNYTNGARGARGARACNGGNCAYYTN ACNCARMGNYTNACNGAYACNAARTCNMGNYTNGAYTGYGARYTNGARMGNYTNAARAGY CARGTNTGYGARYTNGARGARTCNAAYTCNTGYYTNGGNCARAARYTNTCNAAYAARGAR MGNCARATGGCNCARCARGARAARGCNTTYTTYCARAARATGGARTGYGTNGGNMGNGAR AAYYTNATGYTNCARAAYAARYTNAGYGAYAARGAYTAYCARATHCARGCNACNAARGAY TGYATHACNGTNAARGARTCNGARATHATGMGNYTNAARYTNMGNYTNTGYAGYAGYGAY MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GARGARGAYAARGAYTCNAGYGARAGYMGN GCNYTNGCNYTNGTNCCNTAYCARGARGARAAYATHTTYCCNCAYCARAARAARAGYMGN AGYTTYMGNATHGGNGGNTAYGAYTTYCAYATHGARCARGAYTGGACNGGNGGNGGNGTN GCNGCNGTNGTNTGGGAYGCNGCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TCNCAYYTNGTNTTYACNTAYGGNACNYTNAARMGNGGNCARCCNAAY CAYCCNGTNATHGTNGAYAARGARAAYGGNTCNGCNACNTTYYTNGGNTCNGGNGARACN GTNCARGCNTTYCCNYTNGTNGTNGGNACNGAYTTYAAYATGCCNTTYYTNATGCCNGTN GARGGNCARGGNCAYAAYGTNCARGGNGARGTNTAYYTNGTNGAYGAYAARATGYTNGCN TTYYTNGAYGARTTYGARTCNGTNCCNCAYYTNTAYGTNMGNAAYAGYACNAAYGTNTCN YTNACNCAYGAYGCNGARGGNAARCCNATHYTNCARCCNCCNGTNAARAGYTGYGGNACN TAYTTYYTNGTNAARGTNCAYCARGGNATGATHGGNAAYAARTGGYTNTCNTCNTAYAGY TCNGTNTCNGARGAYCAYGGNYTNTAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------CCNACNCARTTYTGYTCNYTNTGYAARTGYAAYACNGARACNMGNAAY ACNACNACNATHAARGTNGTNGTNATHTTYATHATHTGYGTNGTNTCNYTNYTNTTYGTN TAYATGYTNTTYYTNYTNTGYYTNGAYCCNYTNYTNCARMGNMGNCCNAAR---TCNTAY CARCCNCARACNACNGARGARYTNAAY---------ATGCCNCCNCARGARTTYGARGAR GARTTYTCNTCNMGNACNTCNGAYGARCCNGGNCCNTCNGCNGARTCNYTNTCNGCNMGN CARMGNTCNYTNYTNAAYATHGTNACNAARGARCARAARAARTGGAARGGNACNGTNCAR GARCARMGNMGNAAYATHTAYGAYMGNCAYTCNATGYTNAAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GTNTGYGTN GAYATHTCNACNTCNGCNTGYCARYTNACNCARCAYAAYGCNGCNGARGTNGGNGTNTCN GARMGNATHMGNATHYTNCAYGGNGAYTTYATGCAYCCNCARGTNGTNTCNMGNYTNCAR GCNYTNGGNCCNTTYTGYYTNYTNGTNAGYAAYCCNCCNTAYATHCCNACNGARGARGTN AARACNYTNGCNCCNGARATHACNMGNTTYGARGAYAARMGNGCNYTNGAYGGNGGNYTN GAYGGNYTNGAYYTNACNMGNCAYATHYTNMGNTCNGCNMGNCAYYTNGTNGCNTCNAAY GGNTTYGTNGTNYTNGARGTNGGNGARACNCARCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AARGAYGGNGCNGCNATHMGNMGNYTNCARGARGCN YTNCARAARYTNCARAAYGAYYTNGAYAARGTNMGNAAYTCNATHGAYAAYGTNYTNGAR GARAAYGARGARMGNAARAARGARATHCARTCNYTNGGNAARACNTGYGAYAARYTNGAY AARACNAARGCNGAYAARGARTAYGTNGAYACNGARGTNGAYGTNAARGCNGAYMGNMGN CARYTNGARGGNAARGTNAAYCAYAGYYTNTTYGAYACNACNACNAAYGARYTNAAYMGN ATGATHAARGAYATHYTNGAYAARYTNAAYGGNCAYGARGARGGNTGGAARTCNGCNYTN GCNAARGCNATGGARGARYTNGAYGGNAARYTNGAYMGNATGGARYTNMGNAAYYTNAAR GAYTGGYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNYTNATHGTN ACNYTNGTNATGATHTTYTAYTTYAGYCCNMGNTAYGGNCARAARAAYGTNYTNGTNTAY ATHACNATHTGYGCNACNYTNGGNGCNTTYACNGTNATGGGNTGYAARGGNGTNGGNACN GCNATHACNGCNACNGCNMGNGGNCAYAAYGARTTYAARAAYTGGYTNACNTAYGTNYTN TTYGCNGTNGTNATHGTNTGYATHYTNYTNCARYTNAAYTAYYTNAAYAARGCNYTNGAY ACNTAYAAYACNGCNGTNGTNACNCCNATHTAYTAYGTNTTYTTYACNTCNTGYGTNATH GTNGGNTCNGCNATHYTNTTYAARGARTTYTTYAARATGGAYYTNATGAAYATHATHGGN GAYYTNTGYGGNTTYTTYGTNATHGTNATHGGNATHTTYYTNYTNAAYGCNTTYAARGAY YTNAARATHTCNYTNMGNAGYATHCCNMGNGCNTCNAARGARGCNGAYGCNYTNGGNTTY AAYGGNAAYGCNGGNAAYAAYAGYAGYCARATHGARGCNGAYTAYAAYTTYMGNYTNACN YTNTCNGTNATHGAYCARYTNCCNGTNACNGGNCCNCCNCARCAYGTNGTNATHATHGTN TCNTTYGTNATHTCNGCNGCNTAYGCNACNACNAARTAYGCNTTYCAYATGGTNGCNAAR TGGACNGARGARMGNMGNGARYTNACNATHGARMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNGARTCNGARTGYCAYCARGTNGAYATGGCN GAYATHGTNATHCCNCCNCCNATHAARACNGCNGAYGTNCCNYTNCCNCCNGGNAAYCCN ---------------TCNGGNAGYAARGAYGAYACNCARGCNGTNGARGAYYTNACNGGN ATHYTNYTNCCNTCNAARTCNTCNCCNGARAAYAARAGYYTNAARGAR---TGYGTNGAR YTNGGNAARAGYAAYGTNAGYTTYTCNTTYAGYAARACNAGYAAYAARATHGCNGCNACN TCNGCNTTYAAYACNGARGARCCNGAYGCNGTNGARGTNCCNCCNTCNMGNCCNYTNGTN CCNYTNGAYCCNCCNCARGAYAARGAR---------------------------GAYCAR AGYCCNGCNAAYGARCAR---------AGYGGNTCNGGNACNGCNGGNAGYGCNTGGAAR CCN------------------------------CCNMGNYTNYTNGARGAYTTYGTNCAR GTNACNYTNATGAARGARGGNGCNGGNGARATHCCNTGGCCNGTNGARACNATHMGNCAY ACNAGYACNCARCCNAGYYTNCARTAYGCNTGYAAYCCNATGCARTTYGAYTTYAARGAY ATGATGAARAAYCCNGGNATGGGNCARMGNGARGAYGAR---------GCNACNGCNACN YTNAAYYTNGARGCNGGNGAR------------GCNACNGGNGARAARGARGCNMGNCCN AARAARAARCAY---TCNMGNAARAARMGNAARMGNAARAARGGNGGNAARGARGTNGGN GARGGNAAR---TCNGARAARGARGGNAARGARGGN---GARGAYAARGARAAYYTNCCN GGNGAYAARGARGARAARAARGAYAARAARAARAARMGNAARMGNAARAARAARGGNAAR AGYMGNCAYAARTCNGGNAARGAYCARGARGARGTNGGNGARGCNGCNGGNCCNGTNGGN AGYGARCCNTCNGCNGARGGNAARTCNAARAARAARGTNCAYMGNAARMGNACNCAYAAR GARMGNGAYGCNGCNACNACNGARGGNGCNGGNGAYGARAARGARAARGARGGNGAYGGN ACNGARGCNGTNGTNAAYGGNAARAARAGYTCNTCNTCNCAYAARCAYAGYAARCAY--- ---AARMGNAARMGNAARCAYCAYMGNMGNMGNGCNGARAAYTCNGARAARGCNAARGCN YTNAAY------------GCNTCNGARAARGCNAARGTNGAYAAYGTNGAYGCNACNAAY CCNAARGTNAARATHGAYTAYGAYGARGARGARGARGCNCAYATHCCNACNGAYACNGAR CARGAR---AGYGGNGARCCNAARATGAARAARCCNTGYMGNTCNAARAARCARCAYMGN MGNAGYAGY------------TCNYTNAARGARACNGGNCAYGCNGTN---GTNAARACN GARGAYGAYCCNAGYATHACNTTYAARACNCAYAARAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ACNACNCAYTTYAGYGGNTAYTTYTGYACNAGYTGYGARAGYAARGCNAARYTNCCNTCN ATHTAYGCNMGNGTNTTYGGNTCNCAYATHCARATHAARTCNAGYMGNMGNGARGTNMGN YTNATHYTNTAYATHTGGGAYMGNMGNYTNAAYATHAARGAYTTYATHGARGCNGTNAAR CARCARGARTGYGAYATGGAYMGNCARYTNYTNGCNGAYGARTCNGTNCCNYTNYTNGAY AAYGCNACNTCNGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MGNATGGARTCNTGGAARACNAAYGAYCARYTNATHGCNYTNGAYGARGARYTN AARGCNYTNAARGARATGAARGARGGNTCNCAYTGYGARMGNTGYTTYCAYGARGGNACN AARACNAARCAYACNGAR---GGNTGYTCNATGTGYYTNCCNGAYTGYGTNTGYAARGAR MGNCARAARGAYTGYTCNGAYAAYGCN---------------TGYTCNTGYMGNTAYCAY AGYYTNAARACNAARATHAGYCCNTTYTGGACNGARYTNACNGTNMGNGARTCNGCNYTN AARYTNGAYGGNTTYCCNTCNAARGAYGTNAARGARGARTTYYTNAAY------AGYTCN GCNYTNCCNCCNYTNGAYATGACNATGAARACNCCNAAYTTYAGYGARYTNACNAGYYTN YTNMGNACNTCNTTYAARYTNGCNACNGCNGAYATHGARAAYYTNGCNGTNGCNTAYATH AARATGTGGYTNTAYGGNGARGGNCCNGAYATHAARGTNATHCCNGTNGGNGAYATGAAR AARTGYAARGARGAYTTYAARGARTGYTAYGARGTNACNTTYATGAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CARTTYGARAARTTYAARTCNGAYTAYAARGCNYTNCARACNMGNYTNAAR ACNYTNCCNGAYAARATHTCNCAYGAYGTNATGGTNCCNTTYGGNAARYTNGCNTTYATG CCNGGNAARATHGTNCAYACNAAYGARGTNYTNGTNYTNYTNGGNGAYAAYTGGTTYGCN GARMGNTCNGCNAARCARGCNAGYGARATHGCNGGNMGNMGNATHAARGARYTNGAYAAR AARATHAAYGAYYTNAARGARCARAARGGNYTNYTNGARCCNMGNYTNGGNATHACNTCN GARYTNCARGCNCARGCNGARGGNMGNGGNGAYTAYCARGARATHGTNGARGARTAYGAY GARGARAARGARAARYTNTGGGAYAARCARCAYAARGTNAAYGTNMGNMGNAAYAAYGAY CARGAYCARGTNCARAAYAARCAYYTNGCNGAYMGNAAYGARGCNTCNAAR--------- TCNGCNATHACNGAYGAYGARYTNTGGTCNMGNYTNGARGCNYTNGARAARCARGARGAR GARMGNAARGARYTNAAYAGYGAYTCNGAYACNGARGARAARGCNTCNGAYATHGTNAAY MGNMGNGARGARAARGAYCCNGTNATHMGNGARACNATHTCNTAYTCNAARGAYAARMGN GTNAGYTGGATG------------GAYCARGGNGARGARGCNAARGAYAARCARCARTTY CAYAARCARAGYGAYGAYGARGARGARGAYGAYGARGAYTGYGAYGARAGYGAYGARAGY GARGARMGNAAY---MGNCCNGTNGTNAARACNATHMGNTTYTCNCAYACNAARTCN--- YTNATHACNCARYTNCCNGARTCNCCNGCNTCNCARATHACNAGYCCNGCNGAYATHTAY AARYTNTTYTCNCCNAARCCNATHYTNAARAARCAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY ACNCCNYTNATHMGNYTNCAYAARYTNGTNYTNTCNYTNAAYAAYCCNGAYCCNMGNAAY AARTCNYTNACNTAYCCNCAYAGYGCNYTNGGNAARYTNTCNACNGTNGTNACNYTNCAY YTNGAYGGNYTNCAYGAYCCNGTNTTYGGNGTNGGNTTYMGNAAYATGACNGCNYTNMGN MGNYTNTCNTGYAAYGGNTTYATGTCNGGNTTYTGYTAYATHGGNMGNYTNMGNCAYAAY GCNTTYCARAAYGTNAAYAARYTNACNTAYYTNMGNYTNCARGCNTGYTCNATHATHGGN MGNTAYGTNGAYCCNGAYGCNTTYTCNCCNYTNGARAAYYTNCARAGYYTNAGYYTNGAR CAYAAYGARGAYATHGAYYTNAARTAYYTNGAYTCNATHTTYAAYGGNYTNAARAAYGCN CCNAAYYTNACNCAYYTNAAYYTNCAYYTNATHAAYAAYMGNTAYTCNYTNGGNGTNTGY YTNGAYAGYTCNGTNATHMGNAAYATHCCNMGNTCNGTNACNGTNYTNTCNGTNCARGAR AAYAGYYTNCARGCNGTNGAYMGNCARGTNATHGARTCNYTNCCNCCNGGNATHCARACN YTNAAYATHAGYGGNAAYCCNTTYGTNTTYGGNACNTAYGTNCARGAYYTNCAYAARATG AARTCNYTNMGNAARYTNATHYTNAAYGGNGARTCNTTYYTNTAYAARATHCCNAARATH TAYCCNTAYACNCARCCNAAYGAYAGYGCNATHAAYGCNGGNGCNGGNTCNAARTGYYTN AAYAAYAAYGAYYTNAAYTCNCCNAARTTYGTNYTNAARTTYCCNCCNAAYYTNAAYACN ATHGARATGATHAAYGCNGGNYTNACNTAYGTNYTNTCNGARTGGACNGTNGAYCCNGAY AAYGTNGTNGARCAYATHAAYATHGGNTAYAAYATGTTYCCNATHYTNCARGGNCCNATH AAYGGNTTYAAYAARYTNMGNAARYTNGAYATHTCNCAYAGYTCNGTNGARACNATHCAY CCNACNTTYTTYGAYACNTTYACNTCNYTNTAYTGGYTNTAYYTNMGNGGNAAYAAYYTN GGNCARTGYATGAARYTNAARCARAAR---CCNYTNTTYTCNAARYTNMGNYTNYTNAAR AARYTNGAYYTNGGNCARAGYYTNYTNGARGAYYTNAAYTTYAAYGCNTTYTCNGGNYTN AARGAYYTNGARTCNYTNTCNYTNGAYGAYAAYMGNYTNTAYGTNTTYCAYGTNAAYATH TCNCAYATGGAYTCNYTNCARCAYYTNGAYYTNGGNAARACNTAYATHTCNACNYTNCCN GARYTNACNMGNYTNATHAAYACNAARATHGARATHGTNGTNAGYATGAGYCARTGYCCN ATHAGYTGYGTNTGYCARAAYYTNCCNTTYYTNMGNTGGATGTCNCARTCNCCNGCNTTY CARMGNGAYTTYAARGAYTAYAARTGYATHTAYGAYATGAARTCNYTNCARCARGGNTAY AAYAARACNGTNCARAAYYTNAAYGGNGARTGYACNGAYCAYTCNYTNGARTTYTTYATH GTNGCNGGNGTNTCNGCNYTNTCNYTNATHTTYYTNGTNGGNYTNATHTGYTAYCARTTY MGNTGGACNYTNMGNTAYYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TCNYTNGGNGAYGTNGTNATHGGNTAYAAYGARGAYGAYYTNGAR TTYGTNAARMGNYTNGTNGCNAARYTNAARAGYAARGGNYTNAGYGTNTGGTAYAAYCAR CCNGGNGAYGAYGGNAARAARACNAGYGARGCNATHYTNGGNTGYAARGTNTTYYTNCCN GTNYTNACNGARGTNTCNGCNGTNGAYAARAAYATHCAYGARCARYTNTCNYTNGCNTAY ATHTCNAAYTCNGCNATHTAYCCNYTNAGYMGNGTNCCNTTYGGNMGNYTNGCNCCNAAR YTNAAYGGNGGNACNMGNYTNATGYTNGCNAARATHAAYTGGTCNTTYATHTTYAARGAY AARGAYTTYGARGARAARACNGARACNATHATHMGNTGYATHGARAARGAYYTNMGNAAY ATHAARGCNGGNTTYGARGCNGTNGCNGAYGARTTYGGNTTYGTNCAYACNCAYGGNATG CAYYTNCCNGTNAGYATGAAYCAYGTNAARGAYGARGARGARAARGARCCNGARTTYGTN AAYTTYACNAARGGNATHGAYYTNTCNGCNGTNAGYAARGARATHCCNTTYTGGGAYTAY CAYTTYAARGGNAARACNGARGTNACNTGGATHGARTTYMGNGAYAARTTYYTNAARGAY TAYGARCCNAARATHGTNGARGGNTTYTCNGAYATGAARGARGARMGNAARAAYYTNTTY YTNAAYYTNATHTAYAARGAYGTNTTYGGNATGAGYAARATHGTNAARCAYTCNGTNTAY GAYMGNTTYTGYAGYAARGTNCAYCCNCAYGCNTTYTTYYTNGARATGCARGAYTAYGCN ACNGCNTAYTCNTCNYTNMGNGARGTNYTNAGYATGGAYAGYAGYYTNMGNATHACNACN ATHCARAGYYTNGGNAAYTTYAARTTYCCNGCNATHGTNAGYGCNYTNACNGARATGYTN AARGAYGAYGAYCCNAAYATHMGNGCNGTNGCNGCNATHGCNYTNTCNCAYGCNGGNAAR AAYAARGAYTCNATHGTNGAYCAYATHATHGARYTNYTNGARGAYGARGAYMGNYTNGTN MGNGARAGYGCNTGYYTNAGYYTNGGNTAYYTNMGNTCNGARMGNGCNGTNTCNTTYGTN GTNGAYMGNTGGMGNAAYGAYCCNATHTCN---------------ACN---GTNMGNGTN ACNCARGTNYTNTCNTCNGCN---------------------YTNAARCCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATGAAYATHCAYTTYCCNGGNAGYCCNCARTCNATGAGYATHTAYGARCARGARCAR CCN---------------TGYTGGAAR------CARCCNAARATHAARAAYATHGAYATG AGYTCNYTNTCNGARGARCAYGGNYTNYTNGAYGAYGCNATHGARGAYAGYTCNYTNAAY AAYTTYYTNACNCCNGARYTNYTNAGYACNATGGCNTCNTCNTCNTCNGGNATGGCNGCN AGYAGYYTNTGGGAYAAYAARAGYGGNYTNGARGARATGCARGGNGCNTCNGTNGAY--- ------------YTNTCNTTYATHTCNTTYAAYGTNGARTCNGAY---CCNATHATHTCN GAYTTYYTNTAYCARGAYTCNAAYGAYAGYAARTAYCCNTCNTTYGAYTTYGAYTTYAAR TCNTTYCARAGYAAYCCNTCNTCNTCNTGY------------------CAYACNCCNGTN CCNACNGARCCNAARACNGAYTCNATGGARACNTCNAAR------GAYACNGCNTTYYTN TCNAGYAAY------------AAYATHCCNACNAARGARTGYATHGGNAAYGAYTTYYTN CARAARMGNTTYCCNATH---AAYAAYTTYCCNCCNMGNACNTCNCARCCNCCNATHGGN GTNGTNTCNCCNGTNAARGTNAGYGARCARGAR--------------------------- ------MGNAARCARTCNTGYAGYGAYYTNTTYCAY------------------GCNAAR AAYACNAARGARTGYGGNCARAARYTNGCNGGNGTNAAYYTNACNGGNTTYAAYGCNTCN GAYYTNACNGARYTNTCNCCNCARACNGTNCCNTGYTTYGAYAGYTCN---------AAY CARAARTTYTCNGTNAARTCNGARGCNATHTAYCCNGAR---TGYAGYATGTCNMGNAAY CARYTNAARMGNTCNTGYGGNGARATHTCNCCNGTNGAYGCNATGACNAGYACNCAYGGN GAYTCNTTYYTNAGYAARMGNAARMGNTAYGAYTCNGGNAGYTCNGCNCAYATGTCNGAR GAY---GGNGAY------------------GARGARGAYAAYGAYAAYYTNGAYGAYGAY AGYGAYGAYGAYYTNGAYGAYGAYYTNGCNCAYATGAARCCNGGNGARTGYGARTCNYTN ATHTGYCAYGGNAARAARCARAARCARTAYTTYTGGCARTAYAAYGTNCARGCNAARGGN CCNAARGGNACNMGNYTNAARYTNGCNGTNGARAGYCCNGCNGAYCCNCAYGTNYTNAAY GGNTTYGARGAYCCNGTNTTYGAYGARGGNAAYACNATGYTNGCNGGNATHMGNCAYGGN GGNAARGCNMGNAARGGNGAYGGNAAYGARGTNACNCCNAAYCCNCAYAARYTNTTYAAR ATHGGNCAYCARYTNYTNMGNYTNAAYAARAARATHAAYGCNTGYCARYTNGGNTCNGAY ATHCCNGARGCNGTNMGNAAYGARTCNMGNAARGARAARAAYAARYTNGCNTCNMGNGCN TGYMGNYTNAARAARAARGCNCARCAYGARGCNAAYAARATHAARYTNCAYGGNYTNGAR ACNGARCAYGGNCARATHAAYAAYGTNYTNMGNYTNATHTGGCCNGCNYTNMGNGARMGN GCNAARCARYTNCARAAYCAR---------CARATHACNGCNGARAARCCNTGYTCNGGN AARAARYTNACNGAYCARYTNGCNGAYTAYATHTCNACNAAYYTNAARGGNATGGTNGCN GGNCAYACNACNGARTAYGTNAAYGARGTNATHYTNGCNGTNGARAARGGNGAYYTNAAR GGNGGNYTNAAYATHAARAAR---MGNAARACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GCNAARGGNCARTAYTTYMGNGAYYTNGTNACNACNGARACNGAYMGNTTYAAYGTNYTN TGYGGNAARTGGAAYGARTAYGTNACNCARGARCARGGNYTNAGYGARGAYGTNTGYGGN CARATHMGNTGYGCNGTNGGNAARGCNYTNYTNYTNATHGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNGARGAYYTNAARAARYTNAARGTNCCNGARYTNAARCARGCN YTNAARGAYAARGGNYTNTCNACNGCNGGNACNAARCCNGAYYTNATHCARMGNYTNYTN GAR------------TCNAAYTCNAGYAARGCNCCNYTNGAYAAYAGYGAYACNGTNYTN GAYGARGAYGARATHYTNAARGAYGARGAYGAYCCNGTNCARCCNGTNGTNACNCCNAAR GCNGCNCCNGTNGTNGTNCCNAARGTNAAYCCNGCNAARTCNGAYTCNGTNACNGCNGAY ACNGAYAARGCNACNACNGCNCCNGCNATHACNACNCARACNGAYGARGCNAARGTN--- ------TCNGCN------GAYACNACNGTNGCNAARCCNAGYGARGTNAARAARYTNACN GARGCNGARMGNYTNAARATGMGNGCNGAYAARTTYGGNGCNTCNTCNGARCARGCNAAR AARGARYTNMGNGCNCARMGNTTYGGNATHGCNYTNTCNGARAAYAARAAYGGNAAYATH AAYACNTCNGCNGTNCCNGTNGAYCCNGARAARATGAARGCNMGNGCNGARMGNTTYGGN GARGCNACNAGY------------AARTTYTCNGARGARGARMGNAARMGNAARMGNGCN GARMGNTTYGGNACNGCNACNACNACNACNACN---------AGYGTNGCNYTNAAYTCN ACNGAYAGYGARYTNGARGCNAARAARAARAARMGNGCNGARMGNTTYGGNYTNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARGCNAAYMGNGCNGTNGTNTTYGTNGAYTGYAARGTNGCN GARATHYTNCAYTGGGTNGGNGGNATHGCNACNYTNTTYGAYGCNGGNGCNGAYGAYGTN MGNGARTTYTCNTCNTTYGARAGYGGNCARGARAAYCARAARAARGCNGTNTTYATHGTN AGYGGNCCNYTNGARGGNGTNACNGARCARACNATHCARGAYATHGTNACNCARAGYCAY TTYCARTAYGTNGTNGTNYTNACNTCNGCNCAYCCNYTNYTNCARTCNAAYGAYTCNGCN YTNGAYTAYGARAAYAGYTCNTTYTTYGCNGAYTTYGARGARTCNYTNCARGARTGGATG GGNAAYATGAAYTAYACNGCNGARGTNCARCAYGTNAAYYTNTTYAGYTGYGARATHTGY CCNGGNTTYTTYATHACNCCNGCNTTYTCNGARYTNTTYCCNYTNYTNTCNTCNGAYYTN TCNCARATHTGYTAYCAR---YTNGGNTCNMGNCARACNMGNGARGCNTCNACNCCNGCN AGYYTNAAYGAYYTNGARATGTCNCAYYTNCCNGAYGGNYTNCARACNCARATHMGNYTN YTNGCNAGYAGYYTNGAYGGNYTNYTNCARTCNATGCARGTNAARGARGAYATHTAYTCN GTNGGNTGYYTNAGYMGNATHGTNGCNACNCARYTNGAYACNTTYCCNCCNGCNAARACN MGNMGNAARGCNAAYCARTCNMGNYTNTCNYTNATHATHGTNGAYMGNACNYTNGAYYTN GCNTCNGCNGTNACNMGNCARACNGARGTNYTNYTNGAYAARATHATGAAYACNYTNCCN TCNYTN---GGNAAYAGYTGYGAYMGNMGNGTNGTNATGGAYTCNYTNTGYCAYTGY--- ---TAYAGYAARTCNTCNAGYATHATHYTNCCNGGNTGYYTNGCNCCNGTNGCNYTNAAR GAYACNCCNCAYCAYYTNACNGCNGCNATHATGAARAARCARAARGARGCNYTNATHGAY ATHAAYMGNAARYTNGTNGARACNGCNTCNGCNGARAARYTNCCNYTNGAYYTNTCNGGN AARGCNTCNMGNATHAARGCNGARCARYTNGAYTCNACNATGTCNYTNTTYAARGGNAAR TAYCCNYTNATHCARAARCAYYTNGAYATGYTNCARGTNGCNATGGCNACNAGYCARACN YTNAARCAYCCNGGNAAYGARCAYTGYAAYAAYATGGTNGCNMGNGARAARAGYGTNYTN CARTCNGTNGCN------------------------GAYTGGGARYTNGARTCNGARGAR TCNGCNTGYCCNTCNGTNTTYAGYATHYTNTCNAARGCNYTNYTNTCNGARATGGAYAAR AGYCCNGARGAYMGNGARYTNACNYTNGAYGAYTTYYTNCAYYTNYTNGTNTAYGTNTAY TCNYTNGTNGAYGGNCAYAAYGARAGYCCNGAYGARGTNCARYTNYTNCARGAYCARATG GCNCARGTNATHATHCARGARAARAAYMGNYTNCCNCCNGTNGTNCARGCNYTNGTNGGN GARAARGTNACNGARGCNATHGTNCCNGAYCARGTNGARAGYYTNTGGGARAARYTNGAR GCNYTNYTNGAYGCNMGNGARAAYYTNAARGAYYTNAAYAAYMGNGTNGAYCCNGGNGGN GCNYTNAGYCCNGCNAGYGTNAARCCNYTNYTNMGNCARATGGTNGARAARATHGTNGAY CCNGCNAARCCNGAYYTNCCNGAYGTNGARTGYAARTCNGGNGGNYTNAARGAYYTNYTN AARTCNGGNTTYGGNYTNTTYAARAGYAGYGCNAARCCNMGNCCNGGNGAYGCNCCNYTN YTNATGATHTAYGTNATHGGNGGNATHACNGGNTCNGARGTNAARCARGTNAARGAYATH GTNAAYTCNGCNAARCCNGGNTTYGARATHYTNATHGGNTCNACNMGNATHAGYTCNYTN GARTCNTCNATHCARAAYYTNATHTTYAAYGAYAAYATHAAYYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNTCNGAYTCNAGYCAR AAYAARATGCCNMGNATHGARACNGARGAYAGYCARGCNCCNATGGTNMGNYTNYTNTGY GGNGCNGAYYTNYTNGARTCNTTYTCNGTNCCNAAYYTNTGGAARGAYGARGAYATHGAR CARATHGTNAARACNCAYGGNYTNGTNGTNATHAAYMGNGCNGGNTCNGAYGCNGARAAR TTYATHTAYGARTCNGAYGTNYTNTCNMGNCAYAARGARAAYATHACNYTNGTNACNGAR TGGYTNAAYYTNGAYATHAGYTCNACNAARGTNMGNMGNGCNATHMGNMGNGGNGARAGY GTNAARTAYGTNGTNCARGAYTCNGTNATHAAYTAYATHAARCAYCAYGAYYTNTAYGGN GTNCCNGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARMGNCARMGNACNAGYTCNGAYGGNCAYTTYGCNAGYTGYCCNATHTCNGGNAGYGTN GARAAYCCNTCNTCNTCNACNTCNTCNGTNTGGTCNGTNYTNYTNACNGARGCNGCNYTN MGNATGGCNAARGTNTCNTGGGAYMGNAARMGNGTNCCNTCNGTNYTNAAYAGYTGYMGN GTNGTNGARCARYTNGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TGYGGNGGNAARGTN YTNATHGTNGGNGAYGGNGAYTTYTCNTTYACNGTNGCNYTNYTNAARYTNTCNGTNYTN MGNCCNGAYCARGTNTAYACNTCNAAYYTNGARACNGARACNTCNATHCARCAYCAYYTN CARGCNGCNGARAAYATGTCNAGYYTNAARGARTCNGGNGTNATGGTNTTYYTNGARACN GAYGCNMGNGAYYTNCAYAAYCAYCCNACNATHAAYAARGARAARTAYGAYMGNATHYTN TTYAAYTTYCCNYTNGCNGAYMGNCAYAAYATHAARAARAAYMGNGCNYTNYTNGCNGAY TTYTTYTCNAGYAGYAARTCNYTNYTNACNGAYCARGGNCARGTNYTNGTNACNYTNTGY AARGGNCARGGNGGNACNCCNGCNGAYMGNCCNATHMGNTCNTGGCAYGAYAGYTGGCAR GTNGCNGCNATGGCNACNAAYGCNGGNYTNYTNYTNAARGARGTNATGCCNTTYGAYCCN ACNGARTTYCCNGARTAYCAYAGYGTNGGNTTYMGNTTYCARGAYAARAGYTTYAAYGTN ACNGGNGCNYTNACNCAYGTNTTYGARGARGGNGARATGGTNCARGAYGAYGAYMGNGGN ACNMGNGGNGTNGTNAAYMGNGAYGGNCARTCNTTYTCNTGYTCNAGYTAYGTNGCNTCN MGNYTNAARMGNGAYYTNYTNACNGARCCNMGNAAYCCNYTNTGYATHYTNAARAARAAR ATHGARGARAGYYTNTCNAAYGTNATHYTNCCNTCNCAYMGNTCNAGYGCNTGGYTNGCN GARGARACNGGNCCNGCNMGNTGYGAYAARGAYTGGAARGAYAGYCAYAARTCNCARYTN GCNCAYGGNGTNAGYGARGAYAGYAARGARYTNAAYGGNMGNATGGAYAAYCAYYTNGAY TCNGAYYTNCCNAARGAYAAYGARAGYGTNTAYATHYTNGTNMGNAAYGTNACNCAYCAR AAYYTNGARGTNGCNGARGCNGARGAYGGNATGATGGCNGAYGGNGAYGTNTCNTCNGAR GGNATGGAYAAYGAYCARGAYCARACNGTNTAYCAYTGYMGNACNTCNYTNTTYGARAAY YTNCCNCAYYTNCCNCARGAYTCNTCNAAYGGNTCNTCNCAYTGYTCNACNACNTCNGGN GTNGARAGYATGGAYGGNTCNGTNCCNTCNTCNTCNCCNTCNTGYYTNATGTGYGGNCAR TGYATGATHCCNTGYCCNATHTCNCCNAGYTTYGTNCCNACNAARCAYGARATGYTNATH YTNCAYGAYCARTCNAGYTTYGAYGGNTGYTCNTCNMGNATHYTNTCNTCNTCNMGNAAR YTNTCNMGNAARATHGCNGTNAAYACNATGGARGARTCNCARGTNCARYTNATGATHGGN GTNGARAAYGGNGCNGTNTCNTCNGARYTNCARMGNTGYTTYGGNTGY------------ ATHGTNTGYACNMGNYTNGGNGAYTCNTAYTAYCAYGCNACNGTNATHAAYYTNGARTAY YTNYTNTGYGGNYTNTGYAGYGTNGAYGAYCCNMGNYTNATHTGGTCNYTNAAYGARAAR TTYYTNAAYCARTTYCARGCNGAYATHTCNMGNTGYCAYTTYAAYCCNTTYAGYYTNTAY CCNATGAARTTYGTNCAYGAYYTNAGYTTYTGGGARAARGARTCNGAYTCNGAYCARTTY GAYGTNGARGTNYTNTAYGARGCNGTNMGNAGYGTNGTNGGNGAYGTNGTNGTNAGYGTN TGYYTNGTNGAYGTNTAYAARGARCCNGGNACNGARMGNMGNAGYMGNTGYTAYMGNYTN CAYTTYGTNTCNMGNGAYAARTGYYTNCCNTAYGTNATGTCNTGGAARYTNCARAGYMGN GTNMGNATHGARGTNGCNAARMGNYTNGGNGTNACNYTNMGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ AGYTGYATGGTNAARGCNMGNYTNGTNTTYAGYGGNATHGGNGTNTTYGTNGGNATGTCN GCNGCNGCNGTNTTYAGYGTNCAYTAYAARAAYTAYAAYGCNGGNGTNTGGGGNYTNTGY TCNGGNYTNGCNGCNYTNGTNGCNTTYTTYGTNTCNGTNTCNTAYATHMGNGGNTTYTGG GAYGCNAAYCCNYTNATHYTNAARAARTTYATGYTNTCNGGNTGYTTYATHCARYTNGCN GGNGTNTGYGGNTTYGTNGCNTAYYTNGTNYTNGCNATHTCNAARCARCARGGNYTNGTN GCNTAYGGNGCNGGNTTYTAYYTNACNTGYGTNTGGTGYTTYATGACNTGGAARTGGGGN TTYYTNYTNYTNATHTAYTCNMGNACNTAYTTYTAYGGNTAYATGAGYGARGCNGAYCCN TCNTCNTAYTCNGARCCNTCNAARTGYGTNATGAARCARYTNAAYTGGAAYGTNTGGATH GAYTTYGARGCNCAYAARATHAGYGGNGTNGCNAGYYTNTCNTTYGARAARAARGTNGAY AGYYTNAARGARYTNYTNYTNGAYATHMGNGAYYTNAGYGTNCARTCNGTNMGNYTNCAR GGNMGNGAYGAYAARYTNTCNTTYGTNATHGAYAAYCCNACNAARGTNTCNTTYGGNTCN MGNYTNGCNGTNGCNYTNCCNGCNATHCARGGNCARAAYTTYACNYTNGAYGTNGARTAY AGYACNTCNAGYACNTCNTCNGCNYTNGAYTGGYTNACNCCNCARCARACNGCNGGNAAR AARCAYCCNTAYGTNTAYAGYCARTGYCARGCNATHCAYGCNMGNAGYYTNTTYCCNTGY CARGAYACNCCNGCNGTNMGNTTYACNTAYAARGCNCARGTNMGNGCNCCNAARGARATH ACNGTNYTNATGAGYGCNAAYMGNGGNGARGTNACNCCNGCNCCNGAYGTNCCNGGNCAY TGYGTNACNCAYTTYTCNYTNGAYATHCCNATHCCNAGYTAYYTNYTNGCNGTNGTNGCN GGNGAYYTNGARTCNMGNGARATHGGNCCNMGNACNMGNGTNTGGTCNGARMGNGARTTY GTNGARGCNGCNGCNTAYGARTTYGCNGARACNGARTCNATGYTNMGNACNGCNGARGAR YTNATGGGNCCNTAYATHTGGGGNCARTAYGAYYTNYTNGTNYTNCCNCCNTCNTTYCCN TAYGGNGGNATGGARAAYCCNTGYYTNACNTTYGTNACNCCNACNYTNYTNGCNGGNGAY MGNTCNYTNGTNAAYGTNGTNGCNCAYGARATHTCNCAYAGYTGGACNGGNAAYYTNGTN ACNAAYGCNAAYTTYGARCAYTTYTGGYTNAAYGARGGNCAYACNGTNTTYTTYGARMGN AARATHCAYAGYAARYTNTAYGGNGARCCNATG---MGNCARYTNAAYGCNCAYGCNGGN TGGYTNAGYYTNYTNAARACNATHGAYAGYYTNAAYGARTCNGGNGARGCNGCNTAYACN AARYTNGTNCCNGAYYTNTGYGGNGTNGAYCCNGAYGARGCNTTYTCNAARGTNCCNTAY GARAARGGNTTYGCNYTNYTNCARCAYYTNGARACNYTNYTNGGNGGNCCNGAYGTNTTY AAYCCNTTYYTNMGNGCNTAYATHGARCAYTTYAARTTYAARTCNATHTTYACNGARGAY TGGAARAARTTYYTNTTYGGNTAYTTYAAYTCNGCNAARGAYCARGCNAARYTNCARGCN GTNGARTGGGAYAARTGGGTNCAYGCNGARGGNGTNCCNCCNTTYTCNCCNGAYTAYGAY YTNAGYYTNGCNAARCCNAGYYTNGAYYTNAGYCARMGNTGGATGGAR------TCNGAY AARCCNGGNGGNTTYTCNTCNGAYGAYYTNAARGGNATGGAYAGYGCNATHGTNGARGAY TTYYTNACNCARATHTCNAARGCNGARCCNCCNGTNTCNCARAAYAARGTNCARCARATG GARTCNGTNTAYCAYTTYAAYGAYGTNAARAAYTCNGARATHMGNTTYAARTGGYTNACN YTNTGYGTNCARGTNAARTGGAARGARGCNYTNGARTTYGTNTTYAARTTYYTNAAYGAR CARGGNMGNATGAARTTYGTNYTNCCNYTNTAYMGNGAYYTNAAYAARTGGGARGARGCN MGNCCNYTNGCNATHGAYAAYTTYAARACNCAYAARGCNCARATHCAYAGYACNACNGCN AARAARATHGARAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNGAYGCNYTNACNGCNTTYGGNAARAAYCCNAAYCCNCARGARATHCCNTCN ATHYTNGARCARTAYYTNAAYTGYGTNGCNAARAAYGGNGARACNYTNTTYTCNTGGTCN CARYTNAARCCNYTNATHYTNMGNAARATGGARYTNGTNATHATGGARYTNMGNMGNAAY YTNGCNTCNGARAAYATHCCNACNMGNCCNAAYGTNGARAAYGTNMGNTTYGAYGTNATH CAYGCNMGNATHATHGAYTCNYTNCAYAARTTYAAYGGNGCNCCNTTYACNATHCARMGN YTNTGYGARYTNYTNYTNGAYCCNAARMGNCAYTAYAARMGNAGYGAYAARTTYATGMGN GGNYTNGARAARAAYGTNYTNGTNGTNAGYACNGTNGAYCCNTTYGGNMGNAARGTNGTN TGYGAYTCNGGNAAYAARTCNATGGTNAAYGGN---ATHGGNGARTTYAAYGGNTCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CCNCARYTNGGNGAYMGNTAY TAYGGNGARTTYTAYYTNGAYCAYGAYTAYAAYCARTCNMGNTCNGGNAARGARGGNMGN MGNTGYMGNTTYATGATHGGNTCNMGNCARTGYGTNAAYMGNTAYYTNCARCARTTYAAR GAYYTNTTYACNGARGARGGNAARYTNCARATGAARATHACNATHMGNAARGCNAAYGAR CCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CCN AARGCNTCNACNTCN------------CARGARGAYCARGAYAARGAYAARGARTCNCCN TCNTCNCCNAARGARYTNGCNGCNAARCCNGARTCNTCNACNCCNTCNACNTCNGGNGCN GGNCCN------------TCNACNTCNTCNGGNTCNCCNGARGAYMGNAARMGNAARAAR TCNATGGAYGARGAYTAYAARCARGARATHATHAARMGNATGAARAARCARGAYGARGAR MGNATGAARATGCARGTNYTNGTNTCNAAYTTYTCNGARGARCARYTNAAYMGNTAYGAR ATGTTYMGNMGNGCNACNTTYCCNMGNGCNTCNATHAARMGNYTNATGCARAGYATHACN GGNAAYACNGTNTCNCARAAYGTNGTNATHGCNATGTCNGGNATHTCNAARGTNTTYGTN GGNGARGTNYTNGARACNGCNYTNGAYGTNAGYGARAARTGGGGNGAYTCNGGNCCNYTN CARCCNAARCAYYTNMGNGARGCNGTNMGNATHYTNAAYGCNAARGGNATGYTNCCNTCN ACNAARAGYAARAARAGYYTNTTY---------ATGTCNGCNACNNNNGTNCARGTNNNN AGYGCNAAYAARAARGGNGCNYTNCCNTGYYTNYTNACNGGNAAYCCNAARACNACNCCN AARGGNYTNATHGTNYTNCARGARTGGTGGGGNATGAAYGAYCARATHCARGAYTGYGGN AARGAYYTNTGY---GGNCARGCNAARGTNGTNACNATHGTNCCNGAYYTNTAYMGNGGN AARGTNACNACNGAYAAYGARGARGCNGGNCAYTTYATGGGNGAYYTNGAYTGGCARGGN GCNGTNGCNGAYATHCARGCNGCNGCNAARTAYYTNAARGCNCARGGNGTNNNNAARGTN GGNGTNACNGGNTTYTGYATGGGNGGNGCNYTNGCNATGGCNGGNGCNGCNYTNGTNCCN GARGTNGAYGCNGCNGTNCCNTTYTAYGGNATHCCNTCNGCNGARYTNTGYGAYGTNACN AGYATHAARGTNCCNYTNCARTGYCAYTTYGCNAARAAYGAYCARACNAARGGNTTYGCN TCNCCNGAYGARTGGMGNCCNYTNAARAARAARYTNGARGARAARYTNAARGTNYTNGAR TTYTAYGARTAYGARGCNGGNCAYGCNTTYACNAAYAARACNGGNCCNAAYTAYGAYAAR GCNTCNTGYGAYYTNGCNTTYTCNMGNATGGTNGCNTTYYTNGAYAARCAYYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGGCNGAYTGGACNTCNGTNMGNGAYGCNYTNAAYMGNYTNTCNGTN TCNGAYATHAGYGAYGTNTGYCAYYTNATHATHGARTCNTTYTGYCARGAYCARGTNGTN AARTCNAAYGARATGCCNAGYCARTGGAGYYTNGARGARTGGTGGGCNGTNMGNTCNGCN YTNYTNTCNYTNATGMGNAARACNGTNCARAARGAYTGGACNAARGAYCARYTNGCNCAR GAYYTNGARGGNGTNGAYGCNAGYCARMGNGCNGCNGTNACNGARGCNGTNTGYGTNCAR MGNTCNTCNYTNMGNCARAARYTNGTNAAYGARACNACNGCNATHTCNAAYGCNGTNYTN TCNAAYTTYGAYTGGMGNYTNCARYTNGCNYTNTCNAGYGAYMGNATGTCNAGYYTNCAY CARCCNYTNYTNACNYTNGAYYTNGAYYTNAGYGGNGCNGAYGGNGAYMGNAARCARGTN YTNYTNGARATGAAYMGNGAYGARYTNACNTCNYTNATHTCNTCNYTNGARAGYTGYAGY AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AGYTTYTCNGARATHYTNCARGARYTNGGNGARGCN TCNAARATGGTNGTNYTNCARTTYTCNCARTCNYTNAAYGAYTGYYTNGARTAYGARCAR GAYGGNYTNCARGCNGTNCARAAYYTNACNGCNCAYGCNGAYGTNYTNGARAARMGNYTN ATHGGNCARAARGGNYTNYTNTGYGAYMGNYTNMGNACNATHACNAARCAYYTNAAYAAY GAR---CAYGGNGGNCAYGGNGARGCNGGNGAYAARAARCCNYTNGARTTYTCNTCNGAR ATHMGNAAYAARGAYCAYATHYTNGAYCAYYTNTCNCAYATGATHGCNACNAARCCNAAR GAYCARTGGTCNGAYGARGARYTNGARTTYCAYTAYTTYAARYTNCAYGAYAAYGAYCAY AAYAAYAARYTNGAYGGNACNGARATHGGNAARGCNYTNACNCAYTTYCAYGARGARTCN GARTCNGAYCCNAAYGCNMGNTAYATHGCNTTYAAYGAYGAYGAR--------------- ---------YTNGARTTYGCNATHGAYTCNGCNYTNAAYGAY---GAYYTNGAYGAYAAY GGNTAYATHGARTAYTAYGARTTYACNYTNGCNCARGCNAAYCCNMGNYTNAGYAAYGGN CCNACNMGNGTNGGNGAYGAYAARCCNCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARTTYGCNGAYTCNGTNGCN GCNATHGARTCNGAYGGNTTYGTNTCNGCNACNTTYAARTCNTCNMGNACNGCNYTNAAR GARGAR---ACNAARGAYTCNYTNGARTCNAGYCAYAGYGAYGCNATHTTYGGNTCNYTN TCNTCNTCNGGNTTYACNATHAARCCNGAYCCNGAYACNAARCCNGTNACNYTNGARCCN CARTCNATHATGCAYCCNAARYTNTTYTGYGAYCCNGARGARAARATGGARAARTGGYTN CAYMGNYTNTCNGAYYTNMGNMGNMGNMGNYTNGARGGNGARGCNATG------------ ------------------------------------------CAYYTNCCNAARGARGGN GARACNYTNACNGGNTTYAARTTYGCNGTNGGNTTYGGNGGNAARGGNGCNAAYCARTGY ATHACNGCNGCNCAYYTNGGNGGNAARGTNGCNATGGTNGGNAARYTNGGNGAYGAYTCN TTYGGNMGNGAYTAYATGACNAAYATGAARACNAAYAAYGTNAAYTGYGARCAYYTNAAR ATHGTNCCNGGNGTNTCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATGTCNTTYCCNGGNMGNCCNCCNATGGGNATGCCNGGN GGNATGCCNGGNATGGCNCCNMGNATGATG---GCNCCNGGNTAYGCNTTYACNGCNCCN GGNATGCCNMGNATGAAYACNATGATGCCNATGCARATGGGNATGATGACNCCNATGATG CARCCNATGATG---------CARCCNCARATGATGCCN---CARCARACNATHAARCCN GCNGCNACNTTYGTNTCNCARGARAGYAGYGCNAARGTNTTYAARGGNGARMGNCCNCCN GTNACNACNGTNTTYGTNGGNAAYATHAGYGARMGNGCNCCNGAYATGATGATHAARCAR ATGYTNCARMGNTGYGGNAAYGTNYTNAGYTGGAARMGNGTNCARGGNGCNTCNGGNAAR YTNCARGCNTTYGGNTTYTGYGARTAYGARGAYCCNGARGCNACNYTNMGNTGYATHMGN YTNYTNAAYGAYTGGTCNATHGGNGAYAARAARYTNGTNGTNAARGTNGAYGCNAARACN AARACNYTNYTNGAYGAYTAYMGNAARAARAARAARGARGARGCNCARAARGARTCNAAR ACNGARTCNTCNGAYGAYAARAARGARAAYGGNGARGARACNGAYGAYGGNGAR---AAR AARGARAARCCNGARGAYGCNAARGARGGNAARGARGARAAY---AARYTNGAYGARAAY ACNATGMGNGARGAYMGNGTNGCNCARGCNGGNYTNGARGCNATHATGMGNGARTAYGTN TTYGARYTNAAYAARGARCCNTAYAARTCNACNGAY---GGNGAYGAYGARAARGARAAR CCNGTN---AARAARGAYAARGAYCCNTTYACNCAYGTNAARGAYACNGGNTTYGARGAY YTNGARATGGARGCNGARAARMGNGAYATHATHAAYMGNGARATHAAYAARTTYMGNGAY MGNCAYAARGGNAARGAYGARGARAARGAYAARGAR---MGNGAYMGNGARMGNAGYATG YTNMGNGARMGNGARMGNMGNCARGARGARAARMGNCARMGNGARAARYTNGARAARATG MGNGARCARMGNGARMGNGARGCNYTN---------------GARMGNGARMGNGCNAGY ACNMGNGTNTCNMGNTCNAARTCNMGNTCNGCNTCNCCNGTNATHTCNMGNTCNMGNMGN MGNTCNMGNTCNMGNGAYMGNGARMGNGARMGNACNAGYMGNGAYMGNTCNMGNGAYMGN MGNAARGARMGNGARCARGARGARGARGARGARCAYYTNGARMGNMGNAARYTNGARAAR AARYTNMGNGARAARGARGCNGCNTAYCARGARMGNYTNAARAAYTGGGARGGNMGNGAR MGNAARAARACNMGNGARTAYGARAARGARGCNGARMGNGARGARGARMGNAARGTNGAR GARGCNMGNGARGCNMGNMGNYTNAARGARTTYYTNGARGAYTAYGAYGAYYTNMGNGAY GAYCCNAARTTYTAYAARGGNAGYGCNYTNCARMGNMGNYTNAARGARMGNGARAARGAR AARGARYTNGAYAAYMGNGAYMGNCARMGNGARAARGARGARTTYGARGARATHAARMGN AARYTNTTYGAYGARGGNCAYCCNGAYGCNGARACNGARGTNGCNMGNATGGARMGNGAR MGNGARGARCAYYTNCARCCNTGYYTNMGNYTNCARGARATHGARCARCCNCCNCCNTCN YTNCCNGARCCNGAYTCNAAYTCNGGNGAYGARGCNCCNGGNAARYTNGARATHCARCAR GTNTCNCCNAARCARTCNGAYTCNMGNACNACNYTNCAYCAR------------------ AAYYTNYTNCCNCARCAR---------------------------ACNACNGARCARGTN TCNTCNMGNTCNYTNTCNACNTCNCCNATHTCNACNGAYTCNMGNGTN---AGYGCNCCN GCN--------------------------------------------------------- ------------------------------------------------------------ ------------GCNCCNAGYGTNAGYCCNGAYTCNAAYAGYYTNYTNGGNGCNCCNACN ATHTCNGAYGGNAARMGNAARAARYTNACNGTNGGNGAYGTNTTYAAYCARGAYGAYGAY GAYAGYAAYGARCCNAARAARMGNAARYTNATHCCNYTNGAYTAYGAYGARGAYAARGAY ATH---GGNGAYAARAARGGNGCNAGYGCNGARGARAARMGNYTNAARATHAARAARYTN ATHGARAAYATHCCNACNGCNAARGAYGARYTNTAYGCNTAYAARGTNGAYTGGGARATH GTNGAYCARTCNYTNATGGAYAARMGNATHATGCCNTGGGTNACNAARAARATHATHGAR TAYATHGGNGARGARGARCCNACNYTNACNGARTTYATHTGYCARAARGTNATHGCNMGN AGYACNCCNCARAGYATHCARAAYGAYGTNGCNATGATHYTNGAYGAYGARGCNGARGTN TTYGTNGTNAARATGTGGMGNYTNYTNGTNTAYGARACNGARGCNAARAARYTNGGNYTN GTNAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARACNACNCARTCNTCNAAYAGYTCNYTNTTYGGNGGNATGAARAARGGN TTYYTNATHGGNAAYAGYAGYTGYAARCCNAAR------------TCNGCNTCNAAYGGN GCNGCNGCNACNAARCARGAYAARCCNAARCAYTCNGCNATHTCNAARGGNGARGGNGAY GCNTCNAARATGAARTCNCARGARGAYATHCCNTAYATHTCNCCNTCNGGNAARACNGAR TCNGGNYTNACNTTYGAYGARGTNCARCARGCNATGGGNGARGCNAARGGNYTNYTNGAY AAYCARGARTGGATHACNGAYGAYYTNYTNACNAARATHGARAARAAYGAYGTNYTNYTN AARMGNTTYAGYGAYCCNCARTTYATGGCNGCNYTNCARGARTTYCARACNAAYCCNCAR GCNGCNATGGARAARTAYAARGGNAAYACNGARGTNGARAARTTYYTNATGGARTTYTGY GGNYTNYTNGGNGAYCAYTTYACNAARTTYGGNAGYAGYAAYGAY--------------- ------AGYAARAARCCNCARACNCARGGNGCNCARAAYCCNCCNCCNCARAARTCNTCN CAYAAYCCNCCNAARGTNGGN---------------------------------GGNCCN AARATHGTNGARYTNGGNGAYGAYGGNAARCCNGCNGCNGAYTCNTCNTCNAAYGGNAAY GCNAARACNYTNAAYAGYATHTCNCCNGAYYTNAARGAYTGYYTNCCNMGNTCNAAR--- ------------------------------------GAYAARCCNGAYATHTCNATHTCN GTNCAYCAYCCNCAYACNCARGCNGAYATHCARGARGTNCCN---------------CCN TCNGAYGAYGARGCNGTNAARCARGTNYTNGAYGAYCCNAARGTNATGGARACNYTNATG GAYCCNAARGTNATGAAYYTNATHCARGTNYTNMGNGARGAYCCNYTNAARGGNCARAAY YTNGTNGAYAARGCNGAYGAYGAYYTNMGNGGNAARATHCARTTYYTNGTNTCNMGNGGN YTNYTNCARTTYCARATGAAYCARAAYAARCCNMGNCCNACNAAYGTNCCNTCNYTNYTN YTNGARGAYAAYGARAAYGARATHYTNTTYCARACNYTNGGNMGNYTNTGYATHACNYTN GCNACNGGNGTNGTNCARYTNTAYYTNGCNGAYCARCCNGAYAARTCNMGNTGGAAYAAR MGNTGYTGYGGNGTNGCNTGYTTYATHMGNGAYAGYTCNAARMGNTCNTTYTTYATHAAR GTNTTYGAYYTNAARAARCARCARGTNYTNTGGGARCARGARYTNTAYACNCARTTYGTN TAYAARGCNCCNMGNGARTAYTTYCAYACNTTYGARGCNCAYAGYTGYCARGCNGGNYTN AAYTTYGCNGAYGARGAYGARGCNGTNAARTTYAARAARGCNATHGAYATHAARYTNAAY GARMGNMGNGCNAARAARCARGARMGNMGNAAYAARTCNGTNCAYCAYAARCAR------ ---------CARAAYGCNGAYCAYAGYACNGGNATGCCNCARMGNATG---GGNCARACN TCNGCN---CCNYTNCCNACNGTNACNGTNGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNTCNTCNGTNCARCAR TTYMGNATHMGNMGNGTNGARATHYTNACNGTNYTNCARYTNYTNAAYATGATHYTNTGG ATHGTNGAYGTNCAYTAYAARTTYATGCCNGTNGCNATHYTNCCNGCNYTNATGATHTTY GTNGGNYTNYTNGGNGGNGCNTCNTAYGTNAAYATHTTYTAYTCNYTNGTNCAYGAYGAY AAYTTYCCNCARGARGAYAARGARYTNTGYATHAAYATHACNGGNYTNTTYATHAAYGCN GGNATHYTNYTNGGNACNGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNAGYCAYATHGARMGNATGCCNACNATGATGGCNMGNCARGCNMGNGTNCARTTYCAR GCNAARYTNACNGGNTTYGARGARGCNYTNGARAARYTNYTNAARGTNGCNAGYGARCAR CARTGYATHYTNTCNGAYGARGTNGTNTCNTAYGCNATHGTNTCNATHYTNAARGAYCCN CAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------GCNGARATHTAYATHATHGAYATHGAYCCNGTNTTYGAYTAYCCNAARCCN ATHYTNCCNAAYGTNAARYTNGTNGGNGGNYTNGCNGTNMGNAAYACNAARCCNYTNAAR AAYCCNTTYAARAAYTTYYTNGARAARTCNACNAARGGNGTNATHYTNGTNTCNTTYGGN AGYATHATHYTNGAYATHCCNGAYTAYATHTTYGAYAARATHAAYTCNGCNGGNATGGAR ACNGGNYTNAAYGTNGTNTGGMGNTCNAAYCAYAGYTCNCCNAAYCCNGAYMGNATHYTN ACNAGYGAYTGGYTNCCNCARAAYGAYATHYTNGGNCAYGARAAYACNMGNYTNTTYGTN TCNCAYTGYGGNGGNAAYGGNCARTAYGARGCNYTNTAYCAYGGNATHCCNATHYTNTGY TTYCCNGTNTTYGGNGAYCARCCNTAYAAYGCNGARMGNGTNCCNGCNCARGGNTTYGGN ATGAARGCNGAYGTNMGNTCNATHACNMGNGAYCARYTNGCNTCNTCNTTYTAYGARYTN YTNACNAAYACNTCNTAYAARAAYAAYGTNATGCARGCNTCNGCNATHTTYMGNCARYTN TAYAARTCNCCNATGAAYGARTCNGCNTTYTGGYTNGAYCAYGTNATGCARTAYGGNGGN GGNTAYATGMGNGCNGCNAGYCARAARATHCCNYTNTAYCARTAYYTNYTNYTNGAYGTN YTNGCNTTYATHYTNGTNACNYTNGCNACNTGYTCNYTNYTNYTNMGNTTYTGYGTN--- ------------------------TCNMGNGGNTTYMGNAGYMGN---MGNATHAARGAY GTNGARGARGTNGARCCNCAYCARATHCCNAARGAYTCNTTYTCNYTNGGNAARTCNACN YTNTTYGTNACNGCNGTNGGNACNTGYAGYTTYGTNGGNGCNATGATHTGGAAYTAYGAR AAYGTNMGNAARGTNTAYAARGARATGGARAARCCNACNCAYMGNAARTTYATGCAYGAR ---------------AARGTNYTNGGNTTYMGNCARCAYATGAAYGCNATHTGGACNGGN YTNGAYTCNTCNACNAARYTNACNTTYGGNATHATHGCNGCNAAYATHGCNGTNTGGGGN YTNTGGAARGTNCCNMGNATHCARCAYACNATGGTNMGNTAYTTYTCNTCNGCNGCNGCN CAYCCNMGNACNTCNATGGTNYTNAGYAGYTTYAGYCAYATHAGYTTYTTYCAYYTNGGN GTNAAYATGTAYGTNYTNYTNTCNTTYGCNCCNGTNGCNATGCAYYTNTTYGGNAARGAR CARTTYTCNGCNTTYTAYATHACNGCNGGNACNGTNTCNGCNTTYGCNAGYATHYTNTGY CARMGNTTYYTNAARMGNCCNYTNTCNGTNTCNGTNGGNGCNTCNGGNGCNATHATGGGN YTNYTNGGNGTNACNGGNGTNATHTAYCCNAAYGCNCARYTNCARGTNGCNTTYATHTCN GARATHTTYCCNCAYTCNTTYTCNGCNGAYACNGGNATHAARGCNATHGTNYTNTTYGAY YTNYTNGGNYTNGTNYTNGGNTGGMGNGTNYTNGAYCAYGCNGGNCAYYTNGGNGGNATG ATHTTYGGNATHYTNTAYGCNAARTAYGGNAGYAARYTNATHTGGGGNAAYMGNGARGTN ATHGTNAARCARTGGCAYGAYYTNMGNGGNAARCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATHGARGARGARGARGARCARGCNMGNGCN AARTCNCARTTYCAYGCNACNACNAAYAARGCNGTNTTYAARACNCCNTTYGTNCCNGAR AARTCNACNAARCCNYTNACNGARATGAGYAGYTTYACNYTNAAYACNGAYAGYMGNTCN GTNAARMGNGARGARTTYAAYCARCAYYTNAARGCNACNGARGCNGARATHGARGCNATH AARMGNCARMGNGARGARMGNCARGCNGTNGARGARAAYGARGCNGTNCARCARYTNMGN CARCARATGGTNCAYAARGCNACNGAYATHAARAARTAYMGNCCNGTNTCNGTNCARCCN TGYGAYAARCCNYTNACN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARCCNTTYGAYATGACNAAR AARAGYMGNATHTAYGAYGARYTNATHCCNGAYYTNGAYGAYGCNGTNGTNAARATHGCN MGNATGMGNAARGCNCARGTNTCNAARTGYGARACNCARGCNCARAARATHGTNGTNAAY ACNGTNAARTAYTAYMGNGAYGTNACNGTNGARAGYGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ACNAAYGGNCAYGTNTCNTCNGAY GGNYTNGAYGGNGAYMGNTCNTGGGARAARCARGCNACNACNTTYAARCCNCCNGTNCAY GTNGGNACNTGYGAY---------------YTNCARGAYGARGGNAAYYTNMGNAARAAY YTNTCNTCNAAYYTNTCNGGNGGNAAYCARCCNGGNAGYATGGARGCNYTNAARAAYATG YTNTTYAARYTNCARAARGARGARAGYTCNGTNAAYGCNAGYAGY---AAYTCNTCNGAR YTNYTNCCNGTNYTNCARGAYTAYGAYTTYGARACNGARCCNGGNGGNCAYTCNYTNGAR AARGCNYTNCAYCAYYTNGAYMGNYTNAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY GGNTGGTTYAAYGAYYTNTGGATHYTNGAYACNYTNACNYTNAARTGGTTYCARCCNATG CARATGAAYYTNGGNGTNCCNACNCARMGNGCNGCNCAYGGNATGTGYGCNGTNGGNMGN AAYATHGTNATHTTYGGNGGNMGNGAYYTNGARGAYMGNCARAAYGAYGTNCAYATHTTY AAYATHGAYACNMGNAARTGGGAYACNGARYTNCARATHAARGGNTCNCCNCCNGCNCCN MGNTCNTTYCAYAGYGTNACNTGYGTNGGNGAYAARGTNGTNGTNTAYGGNGGNMGNGGN MGNGARAAYAAYCAYTAYAGYGAYTTYGAYGTNYTNGAYYTNGARAARAARGARTGGACN AARGCNTCNGTNGAYGGNTAYCARCCNCCNGCNMGNGGNCARCAYTGYGCNGTNACNGTN GARGAYGTNTAYYTNGTNTTYGGNGGNTCNGGNGAYTTYAGYCCNGARACNATGCARTGY CARACNTTYYTNAARGAYACNTTYTTYGTNAARGCNGAYGAYTTYTCNAARGGNAAYAGY AARCCNAAYGGNGCNCCNGCNATHACNTGGMGNCCNATHGGNGGNATHATHGAYATGTAY GTNATGATHGGNCCNTCNCCNTCNGAYGTNATHGGNCARTAYYTNTCNGTNGTNGGNTAY CCNGCNATGCCNCCNTAYTGGGCNYTNGGNTTYCARYTNTGYTGGCARCAYTAYGGNTCN GCNAARGCNACNYTNAARACNGCNGARMGNATGMGNAARYTNGGNATHCCNCARGAYTGY GGNATHTAYTGYGARGCNAARAGYGGNACNTAYAARGCNTAYGAYGTNGGNAARGTNTGG CCNGGNMGNACNGTNTGGCCNGAYTTYYTNTCNCCNMGNTCNCARATHTAYTGGACNMGN GTNATHGCNGAYTTYTAYMGNAARGTNGAYTTYGAYGGNYTNTGGGTNGAYATGAAYGAR ATHACNAGYTTYTCNGAYGGNTCNGTNCARGGNTGYCCNTAYAAYTCNAGYYTNGAYATG CCNCCNTAYYTNCCNGGNGTNMGNMGNGGNGCNYTNTAYMGNCAYACNATHTGYCCNTCN GCNCARCAYTCNGTNTCNTCNCAYTAYAAYGTNCAYAAYYTNTAYGGNATGTAYCARACN ATGMGNACNGCNMGNGCNYTNCARGAYATHMGNAARAARMGNCCNTTYGTNATHTCNMGN TCNACNTAYCCNGGNAGYGGNCARTTYGGNGGNCAYTGGTCNGGNGAYAAYAARGCNTCN TGGTAYGAYATGTAYGCNTCNATHTCNGCNATGYTNCAYATGAAYATGTGYGGNGTNCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CCNTTYATHTCNGCNTCNTCNTCNCAYGTNTTYACNCCNTCNTTY GTNTAYCCNCAYGTNTAYCARTCNCARYTNATHGTNCCNTCNGGNGARAARACNTAYGAR YTNATHGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MGNYTNCCNGTNATHGAYGARACNACNGGNAAY GCNYTNTAYATHATHACNCAYAARMGNATHYTNMGNTTYATGCAYYTNTAYTTYAARGAY YTNCCNCAYCCNYTNTAYATGAARAARTCNATHAARGARYTNGGNATHGGNACNTAYGAR AAYGTNATHACNGCNACNATGGAYATGACNYTNATHAARGTNYTNAAYYTNTTYTCNGAY CAYMGNATHTCNGCNYTNCCNATHGTNGAYAARACNTCNGGNAARGTNATHGGNATHTAY GCNAARTTYGAYGTNATHAAYYTNGCNGCNGARAARACNTAYAAYAAYYTNGAYATHACN YTNGARGAYGCNYTNAAYMGNMGN---TTYGAYAARCARGARGCNGGNGGNAARGTNGTN ACNTGYTAYGCNACNGAYTCNYTNGARGAYGTNGTNAAYAARATHGTNAARGCNGARGTN CAYMGNYTNGTNGTNACNGAYCARACNGGNGGNGTNGARGGNATHATHTCNYTNTCNGAY YTNYTNAAYTAYACNGTNYTNMGNCCNATHGARGARGTNTCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYGAYYTNGTNAGYAARCARGAYAARTCNMGN ATHAGYCAYACNCARGARGCNATHGARATGACNAAR------------GCNGCNGTNAAR CCNTCNAAYTCNCARGAYTCNCCNYTNGGNATHAARGAYTCNGARACNGCNTCNCAYATH CCNAAR------------ACNATHAGYCARCARCCNAAR---------TTYYTNTCNAAR TTYACNCCNGCNGAYGARAAYCCNGAYGTNCARGCNTCNACNTCNGAYAAYAAYGGNGCN CCNAAYGGNCCNYTNTTYCARGGNTCNATHAGYYTNCARCCNTTYMGNAARGARCCNGCN AARCARGCNMGNTAYGAYAARTAYYTNGCNGCNGTNAARYTNGGNATHCCNGAYCCNTAY AARGAYYTNCCNGTNGGNTCNATGACNGARTGGGARAARTCNAARGARAARGARGARTTY GCNMGNTCNGCNMGNYTNTTYMGNCCNATGTCNGCNATGATGTCNTCNMGNTTYGTNGAR GGNGCNYTNYTNGAYGAYAARGGNCARGAYAGYAARACNYTNGAYGGNGGNGAYGTNTCN GAYGARGTNAARGCNGCNGARATGMGNATGTTYGGNAARYTNACNMGNGARGARYTNGAR TGGCAYCCNGAYAARYTNGTNTGYMGNMGNTTYAAYGTNCCNAAYCCNTAYCCNGGNTCN GAYATHGTNGGNYTNCCNTCNGTNAARMGNGAYAARTTYTCNGTNTTYACNTTYYTNAGY ATGGGNGAYTAYCARCCNAARGARTCNGGNGARGCNCCNMGNTCNAAYCCNATHAARGAR GGNATHCCNGGNAARCARGARGARGCNGCNAGYAARCCNATHGCN------AARAARAAR GCNAGYATGGCNTCNGTNTTYAARGTNYTNGAYGAYCCNGAYTTYCAYAARCCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGGARAARGCNYTNGARGCNYTNGARGGNATGTAYAAYAARACN GARAARGAYYTNGAYCAYYTNTCNMGNAARYTNGAYTAYCARYTNGARTAYATGCCNGAR GTNGAYCARMGNACNAAYCCNGTNAARYTNATGAARACNATGGARGGNATHAARACNGAR TAYGCNAAYATHGTNAARGARACNMGNGCNGTNCARGARGCNCARAARGARTTYTCNGAY TAYTTYMGNTCNCARYTNYTNACNYTNACNGARATGYTNMGNACNYTNGARACNAAYACN GGNCARTCNGTNGAYCARAGYGGNTCNACNCARGARGCNTTYGAYCARYTNTCNMGNYTN YTNGGNATHCCNTAYGGNGARYTNGARCCNCARACN------------------------ GGNACNGCNGTNGCNGTNTCNTCNCAYCCNGCNGGNAGYAGYGGNACNGAYAGYGAYACN GCNCCNTCNCARTCNTCNTCNGGNACNTCNGTNTCN---TCNAARACNGAYGARTGYTCN GAYMGNAARMGNMGNGGNAARGARTTYTGYGARATHTCNCARGARGARTTYGAYTCNGTN TCNCCNYTNYTNMGNCARAARATHAARYTNGARGAYGTNAAYAARGTNTAYMGNYTNYTN TGGCARCAYTTYAARCARGARAARAAYATHGGNAARYTNTCNCCNAARGARATGAAYGCN ATGGGNYTNMGNGTNACNGGNGCNACN--------------------------------- ---------------------------------ATGGTNGGNTTYATHGTNCCNAGYTCN AGYYTNAAYTCNTTYGGNTCNATHTGYTAYTGYYTNATHGCNATGGGNGTNCAYGCNTAY GCNTGYTAYAARAAYATHAGYMGNTAYAARGARGCNGGNACNMGNGAYTGGCCNGGNGCN GGNGGNGGN---CCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNGTNTGYTAYTAYGCNAAYTGGGCN AARTAYMGNCCNACNGCNGTNMGNTTYGGNCCNGARCARGTNGAYCCNTTYYTNTGYACN CAYATHATHTAYGCNTTYGCN---GGNATGGCNAAYAAY------GARAARYTNTCNYTN AAYTAYGAYGCNGAY------------------ATHCCNMGNYTNATGAAYYTNMGNAAY AARAAYCCNAGYYTNAARATHYTNYTNGCNATHGGNGGNTGGAAYYTNMGNTCNGARCCN TTYGAYATHATGTCNMGNACNCARACNACNMGNCARGTNTTYATHGAYTCNGCNATHACN GTNATGMGNCARCAYGGNTTYGAYGGNYTNGAYTAYGAYTGGGARTAY------------ ---------CCNACNAAYAARGAYATHTTYACNYTNYTNGTNCARGARACNGARGCNGCN TTYCARAARGARGCNAARGAYACNGGNAAYCARMGNYTNYTNYTNACNGCNGCNGTNGCN GCNTCNMGNGARAARATHGAYGARGGNTAYGAYGTNCCNGCNYTNGGNYTNGTNYTNGAY TTYGCNYTNGTNATGACNTAYGAYYTNMGNGGNACNTGGGARTCNYTNACNGGNCAYCAY AGYACNYTNTTYGCNGGNGAYYTNGAYCCNYTNGAYAARAARGAR---TAYAAYGTNGAY TGGGTNATHGAYTTYTGGAARGAYCARGGNATGCCNAARAGYAARATHGTNGTNGGNATH CCNTTYTAYGGNMGNACNTTYACNYTNTCNAGYAGYTCNTCNACNGGNATHAGYTCNCCN CAYGTNGGNAARGGNTCNGCNGGNACNTAYACNMGNGARAGYGGNTTYYTNTCNTAYTAY GARATHTGYGARAARGGNGGNCCNGGNACNMGNATHAAYMGNCCNGCNGARATGAARGTN CCNTAYATGGTNGARGGNAAYCARTGGGTNGGNTAYGAYGAYCCNGARAGYGTNCARGAR AARGCNTCNTAYGTNGTNAARAAYGGNTAYGGNGGNGCNATGATHTGGTCNATHGAYATG GAYGAYTTYGCNGGNAGYTTYTGYAGYCARGGNCCNTAYCCNATGYTNMGNGCNATHMGN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CARAAYYTNAAYATGAARGGNACNGGNGARGGNAAYTGYGCNTAYGAY TGGACNACNCARMGNTTYACNCARTGYATHAARGARAAYGTNYTNTGY------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AGYCCNGGNAAYTCNAAYMGNGGNAGYAAYGGNTAYGGNCCNTTY TTYCARGARTAYTCNYTNATGGCNGARTTYAAYCARYTNCAYCARCARAARATHCCNGGN ATHTAYGCNATGCCNTCNTCNAARTCNCCNYTNATHTGGTCNGGNYTNATHTTYATHMGN CARGGNYTNTAYCARGGNGCNGCNYTNMGNTTYACNYTNACNATHCCNCAYAAYTAYCCN GAYGGNAGYTGYCCNAARTTYGTNTTYGARCAYCCNGTNTTYCAYCCNATGGTNGAYCCN GARACNGGNGARYTNGAYGTNAARMGNGCNTTYCCNMGNTGGMGNMGNAAYGTNAAYCAY YTNTGGCARGTNYTNYTNTTYGCNAARAARATHTTYTAYAAYYTNGAYACNAARTTYCCN TCNAAYCCNGARGCNGCNGTNYTNTAYGARCARGARCARGARYTNTTYMGNAGYAARGTN YTNGARTCNYTNGARYTNGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CCNTTYAAY GAYATHGGNTAYCCNAAYYTNGAYATGYTNGCNTCNTCNGGNGTNAARTAYTAYGTNCAR CCNATHTGYACNCCNACNMGNATGTCNGGNMGNTAYCAR---------ATHCAYACNGGN YTNCARCAY---------------GGNTAYGCNACNCAYATG------------------ ------------------------------------------------------------ ---GTNGGNAAR------------------------------------------------ ------------------------------------------------------------ ------------------TGGCAYYTNGGNTTYTAYAARACNGARTTYYTNCCNTGGAAY MGN--------------------------------------------------------- ---------------------------------------------------GGNTTYGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNTAYTTYGGNTAYYTN--------------------------------- ------------------------------------------------------------ ---------------------------AGYAARMGNGAYAARAGY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATHYTNGGNTCNGCNCCNGARTCNTCNGCNAARATHTAYGCNMGNGARCCN TTYATHCCNCAYGAYGGNTAYATHTTYYTNGCNGCNGAYTTYCARCARATHGARTTYMGN ATHYTNGCNCAYYTNTCNAAYAAYAARGCNYTNYTNTCNATGTTYTGGAAYCCNGAYAGY YTNGAYGTNGCNGARCAYYTNAARGTNCARCCNGARGARGCNAARCARATHATGCARAAY TTYYTNGCNCARTAYCCNGCNATHGAYTCNTTYACNAARAARTGYTGYGCNTAYGCNAAR GARTAYGGNTAYACNGARACNATHTGYGGNMGNMGNMGNTAYTTYCCNTAYATHAAYATH TCNTCNCCNGCNYTNMGNTCNCARGCNCARMGNCAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TGGYTNCCNCARGARTTYMGNAARAARTAYACNAARATG TTYCAYMGNCAYGGNTTYGAYACNYTNTTYATHAARGGNYTNACNGARAARGAYYTNGAY MGNYTNGGNATHTCNCARMGNGGNCAYGTNCARTTYYTNATGTCNCARATHGCNCARYTN CCNGCNTTYGAY------ATHGARTAYAARCCNACNAAYATHACNGAYTGGYTNCAYGAR ATHGGNYTNTCNATGTAYMGNGAYAAYTTYCAYATHAARACNCCNAARGARATGGARATH YTNAARMGNTTYGARMGNAARGAYATHGARGARYTNGGNATHACNAARGARGGNCAYATH AARMGNYTNATGTAYGCNATHAARATGYTNMGNGAYCCNACNGAYGGNCARCARMGNGCN ATGMGNATG--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNYTNGARMGNTGYGGNGTNATHTCNGAY CAYACNAARAARATGTGYACNMGNTCNATGAARTGYGCNCARCAYACNGAYGARCARMGN MGNCARGTNMGNCAYYTNYTNYTNMGNCARAGYMGNAGYAAYGAYYTNGARGAYACNCAY ATHGAYATHGAYACNTAYGAYGAYGCNGARTCNCARTCNYTNMGNGARTCNYTNCARTGG GARGCNTCNTCNAAYTCNTCNCCNGCNGAYTCNACNTCNACNAAYAAYAGYACNAGYTGY TCNGTNAARMGNTCNAGYACNAAYAARCCN------------------TCNGGNAARTCN AGYAARAGYAARAARTCNAARACNATHAARACNTCNGTNTCNAAYTCNAGYAGYGCNAGY AGYAGYMGNGAYYTNGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR TTY--------------------------------------------------------- ---------------ATHTGY--------------------------------------- ------AARTGYTTYTAYTCNMGNAAYATHTTYYTNACNAARTAYAARYTNCAYGTNCAY TTYCAYAAYGCNGAY--------------------------------------------- ---CARTTYCARAAR--------------------------------------------- ---------GAYTAYMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARTCNATGGAYCAYMGNACNTTYGCNATHCARACNACNTGGGAY GGNCARTGYTTYTGYCAYGAYCCNATHACNGTNTCNYTNGGNGARGCNCCNGAYGAYGAY YTNGTNYTNAARGTNGARGCNCCNTTYTTYAAYAGYCCNGCNAARCCNGAYGGNCCNGCN GGNCARCCNTTYCCNCARYTNTGGGAYTAYGARGTNGTNGARGCNTTYTTYYTNAAYGAY CARGAYCARTAYYTNGARGTNGARYTNTCNCCNCAYGGNCARCAYYTNYTNYTNYTNYTN AAYGGNMGNMGNAARATGGTNAARGAYCARYTNCCNYTNAAYTTYATHGCNACNATHTCN GGNAARCARTGGACNGGNGARGCNAARATHCCNMGNMGNTAYYTNCCNCCNGGNGTNACN AARTTYAAYGCNTAYGCNATHCAYGGNGARGGNGARGCNMGNCARTAYGARTCNYTNTAY CCNGTNACNGARAARACN---------GAYGGNATGCARCCNGAYTTYCAYMGNYTNGAR YTNTTYCARCCNYTNGAYATGAAYTCNGTNYTNAARAAYTAYAAYTCNTCNCARATHTCN AAYYTNTGGGTNCCNTTYATHAARTCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNAGYTAY TCNAGYATHCARTCNATHAARGARGARCAYGAYMGNATHAARCARGARCARTCNCCNGCN MGNTCNGTNAAYGAYGGNGARTCNAAYACNYTNTTYGAYAGYYTNMGNGAYACNATHTAY ACNGARGTNGCNTCNYTNATHTCNCARAAYGARAAYMGNCCNCAYTTY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYCARGTNTCNGARCARGAYYTNGCNYTN AGYAAYATHCCNGAYTAYAARGAYMGN---TAYTAYCCNAAYGCNCARGGNTGGATHCAY ---GAYGGNGARGARGGNTGYMGNCARAARMGNGGNGTNTCNTTYGAYCCNMGNAARMGN AAYTTYACNGARGARGARYTNAARCCNCARCCNATHATHAARAARTCNAARAARATHTTY GTNCCNGARGAYYTNAARGAYGAYMGNTAYTGGGCNMGNMGNCAYAARAAYAAYTTYGCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GTNAARAARCCNMGNCCNATHAGYGCNTCNAGYYTN MGNGARGGNGAYGCNATGMGNTCNMGNCCNAAYAGYGGNCAYCCNMGNAARCARGAYAAR TCNTCNCARGCNTTYATHACNCARAARAAYGARMGNTCNYTNAARTAYGARGCNACNAAR CCNGTNTTYGTNCAYCCNAAR------CARGGNAARCCNMGNMGNAAYTCNGAYGGNCAY GTNACNCARYTNAAYMGNTCNAGYAGYCAYCCNACNYTNATHTCNCARACNGAYGTNATH AGYGCNGCNAGYGCNGCNMGNCCNGAYTAYACNACNGAY--------------------- ---------YTNAGYACNGCNAARGAYGAYGGNGGNAAYGAYCCNACNGAYAAYGGNYTN GCNGAYGAYAAYGAYGGNTAYCCNGARYTNGARCCN---------ATHGTNCARGTNMGN CCNCCNATHTCNATHMGNGTNAARTCNGCNCAYACNMGNMGNCCNGCNCAYATHGAYAAR TTYGCNGAYGARGARMGNGTNATGCARGARATGGAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARAAYGTNYTNGTNYTNCARACNGGNGGNACNATHGAYAARMGNTAYCCN CARGGNCCNGGNGCNTAYGCNTTYGARATHGGNCARCCNGCNGCNGARAARGTNYTNAAY MGNATHTGYCCNAAYTTYATGTAYMGNATHGTNTGYGTNTGYTGYAARGAYAGYCARGAR ATHACNGAYATHGAYMGNGARGAYATGYTNMGNGCNGTNGTNGARTCNGAYCARCARYTN GTNYTNATHACNCAYGGNACNGAYACNYTNTGYGAYACNGCNMGNTAYYTNGCNAARGCN GGNGTNGGNCARGGNGCNCARYTNCARCCNGGNGTNGGNGGNAARACNGTNGTNYTNACN GGNTCNTTYYTNCCNGARGCNATGAARGAYTCNGAYGCNGAYTTYAAYATHGGNTTYGCN YTNGGNTTYYTNCAYGCN---TCNCCNCCNGGNGTNTTYGTNGCNATHGARGGNAGYATH YTNGAYGGNAAYCAYGCNACNMGNTGYGGNGAYGGNAARTTYGTNGAYGARMGNCARYTN YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CAYYTNACNTTYYTNGARMGNGARMGNGCNAARCCNGAYYTNGGNGAYTTY ACNYTNGCNGARTAYACNGARAARGTNATHYTNTAYGGNTTYYTNATGYTNTTYGCNTGY TCNTTYCCNYTNGCNCCNYTNYTNGCNYTNGTNATHTGYTAYATHGAYATHAARGTNGAY GCNAARMGNATGYTNTGGYTNTAYMGNMGNCCNGTNATHGGNATGTGGTAYGAYATHYTN AAYYTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGYTNTCNMGNTCNGGNMGNGCNGARACNMGNAGYMGNGCNAARGAR GAYATHAARMGNGTNATHAAYGCNATHGAYAARGTNMGNAARTGGGARAARAARTGGGTN ACNYTNGGNGAYACNTCNGTNACNATHATGAARTGGGTNCCNGTNACNGCNCARGARAAY CCNGGNGCNYTNMGNAARATHCCNGGNGTNAARACNAARACNTAYTCNAARGCNMGNGTN GARAARGARMGNGARYTNTTYAAYGCNGARACNAAYGGNGGNGGNTCNGTNAAYTCNCCN GCNGAYTCN---------AAYGCNAAYGCNTCNAAYACNAGYTCNCCNTCNTCNMGNTCN CAYCAY---AAYGGNGAYAARGCNAARAGYTCN------ACNAAYTCNCAYGGN------ ATHTAYTCNGARGARAAYACNCARCARTCNATHGGNTCNTGYGGNTCNGARAAYYTNAAY GARGAYTCNAAYATGTCNTTYCCNGARAAYAGYGARCAYAGYGARCARGCNGAYCAYAAY GARTTYTCNCAYGAYAGYAAYGAYGCNGAYCCNGGNATGMGNGTNGCNATGAGYATGGTN GGNGARGARGARGARTCNAAR------------GARGARAGYAARGAY------------ ------------------------------------------------------------ ATGTCNGARAARCAYGAYTTYGGNGTNGCNCCNGTNACNTGYCAYGCNTTYAGYGCNGAY MGNAAYGGNYTNGCNATGTCNYTNAAYGAYTCNAAYGTNAARATHTTYAARAARTCNGGN GCNAARTGGGARGAYGTNGCNACNYTNAGYGARCAYGCNCARMGNGTNACNAGYATHGAY TGGGCNCCNAARACNAAYMGNATHGTNACNTGYTCNGCNGAYMGNAAYGCNTTYGTNTGG ATGYTNGARGAYGGNAARTGGAARCARGTNYTNGTNATHCCNMGNATHAAYMGNGCNGCN ACNTGYGTNAARTGGTCNCCNAGYGARAAYAARTTYGCNGTNGGNAGYGGNTCNMGNYTN ATHGCNATHTGYTAYTAYGAYGAYGARAAYAAYTGGTGGGTNAGYMGNCAYATHAARAAR CCNATHMGNTCNACNGTNACNTGYYTNGAYTGGCAYCCNAAYAAYGTNYTNYTNGCNGCN GGNTCNACNGAYTTYAARTGYMGNGTNTTYTCNGCNTAYCARAARGARGTNGAYGARAAR CCNAARCCNTGYAGYTGGGGNACNAARATGCCNTTYGGNGCNYTNATGGCNGARTTYAGY AAYGGNGGNGGNGGNTGGGTNCAYTCNGTNTCNTTYTCNCCNAGYGGNAAYGTNATGGCN TGGGTNGGNCAYGAYTCNAGYGTNTCNATHGCNGAYTCNTCNAAYAAYAAYGARYTNTGY ATHATHAARGARAGYTTYYTNCCNTTYGTNAGYGTNTCNTGGGTNACNGARAAYTCNYTN GTNGCNGCNGGNTAYGAYTGYAAYCCNATGGTNTTYTCNTTYTCNGGNGGNAARATHAGY TGYCARGGNAARYTNGAYGTNCCNCARCARMGNGARTCNGGNACNATGAGYGCNATGAAY MGNTTYAARAAYYTNGAYAARAARGCNACNGAYAGYGAYAGYTCNCCNGARATGAARACN CARCAYCARAAYACNATHACNCARGTNTCNGTNCAYACNGGNACNAARGCNGAYGCNAGY AARATHGCNACNAGYGGNGTNGAYGGNAAYYTNATHATHTGGGAYYTNAAR--------- ---------------------------------------------------------AAR GTNGARTCNMGNGTNGGNTCNYTNGAYAAYGCNAARCAYGTNGCNGGNGGNGGNGAYAAR AARATHGARTCNCARAARGTNGARTGGAAYGCNGCNTCNAARATHMGNTCNYTNGARAAR GCNAAYCAYAARCCNGGNGGNGGNGAYGTNAARATHGARACNGCNAARACNGARTGGAAY GCNCARTCNAARATHMGNTCNYTNGARAAYGTNAARCAYCARCCNGGNGGNGGNGAYAAR CARATHGARACNCAYCAYYTNGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNAARYTNATHGTNTTYGAYYTNGAYTAYACNYTNTGGCCN TTYTGGGTNGAYACNCAYGTNGAYCCNCCNTTYACNYTNAARCARGAYGGNAARGTNTAY GAYTCNMGNMGNCAYGARGTNAARCAYTAYCCNGAYGTNCCNGARATHYTNGCNAARYTN CAYMGNGARGGNTTYAARYTNGGNATHGCNTCNMGNACNGGNGCNACNGARGAYGCNAAR GAYYTNGTNMGNYTNTTYATHTGGGAYGGNTTYTTYCAYTAYTGGCARATHTAYCCNGGN TGYAARATHACNCAYTTYCARAARYTNCAYAGYGARAGYGGNATHGCNTAYAARGAYATG YTNTTYTTYGAYGAYGARCAYMGNAAYATHACNGAYGTNTCNTCNYTNGGNGTNACNTGY ATGTTYGTNCCNGAYGCNGGNGTNTCNCARAARACNTTYAARGARGGNYTNGAYYTNTTY CARAARAAYAAYTCNCARAARCCNGGNTCNTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AARAAR YTNACNTCNAARATGTCNYTNCARGARGCNTTYCARTTYMGNAARATGGGNTTYATHTCN AARAGYTCNGARMGNCARAARMGNATHAARYTNTCNMGNGARGARMGNCARYTNCARGAR TGYYTNMGNYTNGARMGNGARGCNATHTTYYTNGAYCAYGARMGNATGGCNCCNCCNAAY YTNTAYGCNCAYCCNTAYAGYGAYAAYYTNTAYCARCCNAARCARMGNATHYTNACNAAR CARGARATGAARAAYATHACNGCNAARMGNTAYAARACNYTNTCNGARGTNAARGARAAR AARGARGARGAYMGNAARAARATGGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TGGTGYGCNGCNATHAAYTGY ACNAAYTCNAARAAYMGNMGNCCNGAYYTNTCNTTYTAYGGNTTYCCNAARGAYCCNGAR MGNTGYAARCARTGGATHATHAAYTCNMGNMGNAARGAYYTNGARGARAARACNTCNGAY CARYTNCAYMGNTAYACNMGNYTNTGYGCNYTNCAYTTYGARCCNTGYTGYTTYATHCAR CCNGTNAARGGNAARTTYYTNMGNYTNAARAARGAYGCNGTNCCNACNATHTTYGAYGTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNATGTCNGGNGAYGARATGTTYACNGARACNACNCCNATGACNGARACNGAY GGNTTYTAYATHYTNAARGGNAARTTYGTNACN---AAR---GCNGAYGGNGTNGAYGAR AGYYTNYTNGGNGCNAAYCCNAGYGCNGARGARGCNGCNGARGGNACNGARGAYGGNACN ATGGARTCNGGNGTNGAYGTNATHATHTAYCARMGNYTNCARGARACNGGNTTYGGNTCN AARAARGAYTAYCARATHTAYATGAARGAYTAYATHAARAAYGTNTTYTCNAARYTNGCN GARAGYGGNAARTCNGCNGAYGARYTNGCNATGAARGARAAYGTNGCNATHGCNTTYAAR GARGCNTGYGCNAAYTTYAARGARTGGCARTTYTAYTCNGGNGCNAGYATGGAYCCNGAY GGNCAYATHGCNYTNGTNGAYTGGAARGAYGARGARGTNGAYGGNAARACNGTNAGYACN CCNTAYYTNTAYTTYTAYAARGCNGGNATHAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ACNTAYMGNAAR TTYTAYGGNMGNAARCCNGAYGGNYTNAAYGGNGCNATG--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GTNMGN ATHGARGAYGGNMGNYTNTGGTAYGAYAARAARTGGTTYCARMGNAAYACNATGGTNCAR ATHGAYAGYAARGARGGNAGYAAYMGNATHATHGGNACNATHACNCAYATHGGNAAYCAR GARATHGTNGTNAARAARAGYGGNGAYAGYTCNAARGTNMGNATHTGYYTNTCNCARTTY CARAARMGNAARTAYATHATGAARAARMGNACNAGY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTCNMGNGCNGCNCCNTCNAARACN MGNGGNGCNGAYAARACNAARCCNCCNGCNTCNCARACNCCNGTNATHGCNCAYGARATH GTNCCNGGNAARTTYAAYGAYAAYGAYTGGAAYGTNATGYTNGAYMGNGAYGGNAAYGAY GARTTYGTNATGGAYATHATGGAYGARYTNATGGAYMGNACNATGACNACNATHTTYGAY AAYTAYATHCARMGNCARYTNYTNCCNTTYACNATHACNCARGCNMGNGAYGCNATHATH GARATHATHGARTGGCARTTYYTNGARMGNGAYGARGGNGARGARAGYATHGARAAYGAY YTNGGNTGGACNCARGAYGARGARCCNGARCCNGCNGARACNGAYTGYTGGGCNCARGGN TCNGTNCCNAARAAYGTNATHATHGTNCCNACNCCN------------ACNYTNGARGAR ATHCARGARGARCCNGAR---GARGTNCCNAAYGARGCNGAYAARGARGARGARACNGCN GARCARACNGARCARGARCCNGCNGARYTNGAYGAYGTNGTNTCNGARCCNGAYGARACN CARAARATHCCN---CARCARGAYAARGAYTCNGARAARAGYAARGTN---CCNACNCCN CCNAARACNCCNCARGTNAARCCNAARACNAARTTYAARCCNTAYMGNGGNAARYTNAAR TCNGCNGGNGTNAGYAARATGACNGARTCNYTNGARGARACNGARATGAARATGATHTAY AAYGARATHGTNGCNGCNATGCCNCCNAAYGARGAYCARCCNAGYACNYTNYTNAAYATG CCNGCNTCNTGYACNAGYATHYTNAARGTNCARACNGGNMGNCCNCCNGGNAAYAARGAY GTNGTNTAYGAYGAYYTNGGNAAYGTNGTNGCNGTNATGMGNYTNGAYCCNGARAARYTN CCNACNCAYAARGTNAAYGTNAARTAYCAYGTNGTNGAYCCNGCNGTNGARGCNGCNCAR GCNMGNYTNGAYGCNATGMGNAARGGNAARTCNACNGGN---AARGGNAARMGNTTYMGN TCNAAYAARAGYYTNGTNGCNGARTCNAAYTCNACNGGNTCNAARGCNAARGTNTCNTCN ATHACNAGYGTNGTNGCNCCNYTNCCNCCNCCNYTN------------------------ ---------------------------------ATHGARGARATGGARGTNTCNCAYGGN GTNGTNATHAARGARGGNGGNMGNGTNAARAARGGNCCNGGNMGNTAYTAYMGNAARYTN GAYATHYTNGARGARAAYCARAARGGNATGAARCCNGTNAARGTNMGNATGACNACNGCN GGNATHACNGTNAAYGAYYTNYTNGAYMGNAAYACNCCNATHYTNMGNCCNATGTCNGAY TCNTCNCCNYTNCCNCCNATHGTNCCNCARCCNCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATHGTNAARGGNGAY AAYGGNGAYGTNATGAARCARTGYYTNMGNGAYTCNTGGAARCAYTTYAGYAGYYTNGCN ATGTCNGAYAARGCNAARGAYAGYGGNAAYATGYTNATGTCNGCNATGYTNGGNCAYAGY AARCCNATGGAYAAYGAYTAYGCNYTNYTNAARGARTGYGCNTTYGAYTTYCAYCARATH ---CCNGCNAGYGARYTNMGNMGNMGNGGNTTY---CCNTAYCARATHGCNTAYAGYTGY ACNACNGTNGTNTCNCARCCNAAYGTNTAYATGCAYTGGYTNATGAARGARTTYATHTCN GGNGGNGGNGARYTNCARMGNMGNACNGTNAAYAARYTNGARGARYTNCAYGGNGAYTTY CAYGTNGTNATHAAYTGYTCNGGNYTNMGNGCNAARACNYTNGTNGAYGAYAARGARATG TAYCCNGTNMGNGGNCARYTNGTNATGYTNAARGCNCCNTGGATHAARCARTGYTAYTAY YTNGAYACNGAYATHTAYGTNTTYCCNCAYATGGAYAARGTNGTNATHGGNGGNACNMGN AARGCNGGNGAYTGGAAYACNGAYGTNGAYCCNGARATHGARACNACNATHYTNMGNAAY GCNGARGCNATHTTYCCNGARYTNAARGGNGCNGARMGNATHGGNGGNTGGACNGGNYTN MGNCCNGGNMGNACNMGNGTNMGNYTNGARATGGARACNYTNGAYYTNGGNTAYAAYMGN AARYTNCCNGTNGTNCAYAAYTAYGGNCAYGCNGGNCAYGGNGTNACNYTNAGYTGGGGN ACNGGNGTNCAYGCNGCNAARYTNGCNAARGARGCNYTNTCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CCNTGGYTNTCN GARAARGARAARGARTTYGCNMGNGGNACNGCNGAYTTYTTYGGNYTNTCNTAYTAYAAY ACNCAYTCNGCNCARMGNGAYGAYAAYCCNGCNTCNYTNCCNGTNGARGARTTYCCNAGY GAY------------------------------GARAGYCARGCNACNTGG--------- AAYCCNAARGGNYTNMGNCAYYTNYTNAAYGTNATHAARTCNMGNTAYGAYAAYCCNMGN GTNGTNATHGCNGGNAAYGGNGTNTGGGAYAARGAYGGNGTNACNGAYGAYTTYMGNGCN GAYTTYATHTCNCARCAYGTNGARGARGTNYTNAARGCNAARMGNATHGAYGGNTGYGAY GTNMGNGAYTAYACNTAYMGNTCNYTNATGGAYTCNTAYGARTGGMGNCARGGNACNGAY MGNAARTTYGGNYTNGTNGCNGTNGAYTTYACNTCNCARGAYAARACNMGNACNYTNAAR AGYTCNGCN--------------------------------------------------- ---------------------------------------------AAYACNAAYGAYAAY GAYTGGTAYATHTGGACNCCNATGTAYTTYYTNCCNTCNATHYTNTGYGCNGTNGCNTTY ATHMGNCCNCARGCNATHGTNAAYCARATHTGGYTNGCNTTYGTNTCNGTNGARTTYGCN ATHGCNGTNGCNTTYATGYTNTAYCARACNTCNAAYATHTTYGGNATGTTYAGYACNATG ACNTCNAAYCCNYTNTAYCAYGARGARGGNMGNGARATGGGNGGNYTNATGATHATHYTN YTNTGGACNGGNATHTCNMGNTTYGCNCCNTTYAARAGYGCNMGNGGNCCNMGNAAYAAY GCNATG---AGYGGNYTNYTNGTNATHGCNTTYACNYTNGCNGTNGTNCCNYTNGTNACN TGGTCNYTNTGYTTYGTNGGNGAYTGGCAYAARCARYTNGGNCAYTGYTCNGGNATGTTY TGYTTYACNTGYGAYAARGTNTTYTCNCAYAARGTNAAYYTNAARAARCAYAARMGNGTN CAYGARAARYTNAARCCNCAYAARTGYTTYACNTGYGGNAARGCNTTYGTNGARGTNAAY AARYTNAAYGCNCAYAARMGNGTNCAYGARAAYATHCARYTNCAYAARTGYTGYACNTGY GAYAARGCNTTYTCNGAYAAYTGGACNYTNYTNMGNCAYATGAAYGTN------------ ------------------------------------------------------------ ------------CAYAARAAYATHAARCCNTAYAAYTGYTTYACNTGYGAYAARACNTTY TCNCARATHGCNAARYTNAAYGCNCAYAAYAGYGTNCAYAARAAYATHAARCCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARTCNAGYYTNGCNMGNGAYGGNACNATGCARGTNACNGCNAARGARGGNATHGAYTAY YTNAARTCNGCNCAYAARGAYACNYTNYTNAARGTNCARGGNGTNAARGAYGCN------ ------------------------------------------------------------ ------------------------------------------------AARCCNGTNGTN CARMGNGAYGGNACNATGGTNGCNACNGCNAARGARGCNGAYMGNYTNYTNGARGGNAAY AARCCNGAYGCNGAYGCNCARACNMGNGGNCARCARAARCARATHGAYGARATHAAYAAY GAR---AGYGARCCNAARGCNAARAARCCNMGNYTNGCNAARGAYGGNACNATGGCNGCN ACNGCNAARGARGCNAARGCNYTNYTNGCNGGNGARAARYTNGGNGAYACNMGNCARGAR TCNAARAAY---------AARGCNAARACNCCNYTNAARAARCAYTCNACNATHGCNAAR ACNYTNGARGARGCNAARACNGTNYTNGAYGGNAARYTNGAYACNAGYGARGGNMGNAAR ACNMGNTCNCARAGYMGNGGNGTNGTNCCNAARCCNTCNGTNAARAARCARGGNACNATG CARCARACNGCNAARGAYGGNAARGCNTTYYTNAAYMGNAGYAAR---GGNAARAARGCN GCNAARGCNACNGARGARAARGARGAYGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGCCNAGYYTNCCN ---YTNGTNAARCARGGN------ATGGCNGGNGTNGCNGCNGCNACNACNACNMGNGCN YTN---------AARCARATHATHAARCCNCAYATHCCNATGATHAARTTYCCNAARMGN GARCCNGCNGCNGGNYTNCARGGN---GGNGARCCNATHTCNAAYCCNMGNTCNGTNGAR TCNYTNGTNTCNGCNAGYYTNGGN---------------CCNAARCCNTCNCCNTCNAAR TCNAARGGNTCNTCNATHGARACNTCNGARYTNCCNGCNMGNTTYAARMGNAARYTNATH TCNGTNGARGARATGGARTTYATHGARAARGGNGGNCCNGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNCARATHCAYACNCARGGNTCNCCNYTNYTNTTY CARYTNTCNGARAARYTNTGYGCNGARCCNATGAARAARMGNMGNAARATGGAYCCNGCN ATHGCNGCNGCNMGNACNCARAARAARATHAARAARATHGAYAARGARATHAARMGNYTN TCNAARTTYGGNAARATHYTNAARCCNGTNGARGARATHGARGGNGAYMGNMGNAARYTN ATGGCNTCNGGNGARMGNAARMGNGAYTCNATHGTNYTNACNTTYGAYGARTCNGARTCN MGNGCNYTNYTNCAYAARGAYTGGACNMGNTAYMGNACNAARMGNCAYCAYGARATGATH AARCARTAYACNCARGTNGCNGCNGCNCARCARGARGCNYTNGARGARYTNMGNGCNGAR TCNGARGARYTNTAYCARGCNGCNATHAARATHGAYGAYGAYYTNTTYCCNYTNACNTTY GARGGNCCNAARGARACNCCNCCNATHAARGGNTAYAGYGCNCCNGAYGGNGARTAYGTN GAYATHACNMGNAARTTY---------------GARACNGAYTGGAAYATHGAYATGGAR GTNAAYYTNTTYCAYGCNATGMGNGGNCAYAARCCNGCNGGNGTNAAYMGNCAYTTYCAR ATGATHGCNATHCAYGAYAARYTNAGYTCNTCNAGYAARAARGTNACNTCNAAYGARGTN TGGCARCAYYTNTCNACNYTNTAYGAYYTNCARGCNYTNAAYGARAGYGARATGGTNCCN TTYCCNAAYAARCCNGGNGAYTTYTCNYTNTCNGAYAARGARYTNATGGARYTNTCNACN AARTCNTTYCCNMGNTCNTCNTAYATHAGYGTN---TCNACNGARCCNYTNAARACNGAR AGYTCNGGNAARAGYATHTCNAARYTNAGYACNAARCCNGAYAGYAARACNGGNAAYCAR ACNCCNAARACNGARGCNAARCCNGARAGYAARTCNGTNAGYAGYTCNAARTCNGAYAGY MGNACNAGYACNCCNTCNAGYCAYMGNTCNGAYTCNAARTCNTCNCAYCAYGGNAAYAGY AGYAGYGGNAGYAGYAGYACNTCNAARTCNTCNCAYCAYAGYAGYCAYTCNGCNAAYCCN TCNCCNTCNTCNAARMGNACNAARMGNACNMGNAAYGTNAAYTCNGCNACNGCNAGYCCN GCNACNCCNACNGARCCNCARGCNAARMGNMGNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TTYCAR GTNYTNMGNGTNTTYMGNATHATHMGNYTNAARAARCARATGCCNGGNYTNTGGGTNYTN YTNTAYACNYTNAARTCNAGYATHAARGAYYTNTTYYTNATGGTNYTNTTYYTNTGYGTN GGNACNYTNATHTTYTCNAGYYTNGTNTAYTAYGCNGARMGNGAYGCNCAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CCNGTNTCNYTNGCNACNGTNACNTCNACNCCNCCNCCN--------------- ------------------AAYMGNGARGCNACNCARYTNTCNMGNTCNAGYGCNMGNTCN ATGTCNMGNTCNTCNAGYMGNGCNACNCCNACNGTN------------YTNGCNGGNGGN GARACNACNCCNGTNAAYGTNCCNAAYCARCARCARGARGTNMGNTAYCARYTNCARGAR YTNCARGTNYTNTCNMGNGCNGCNGARGTNGARMGNGAYAARATGTCNGARYTNGTNCAR GTNYTNCARACNMGNYTNTCNGARGARGTNGARMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GCNGAY GTNGARGAYYTNATGGCNTCNYTNATGACNAAYATGGCNAAYGTNGARGARAARATHGGN YTNGARCARGCNMGNCARMGNMGNGCNYTNGARCARMGNYTNGCNMGNMGNAARCARGCN GTNGARTAYCARCARYTNGARAARGARGARAARGCNAARGARCARGAYGARMGNGTNAAR ACNYTNMGNACNYTNYTNGARCAYCAYGCNAARGAYGGNTCNYTNYTNGARAARCARCAR GAYACNGTNGTNAAYGARTAYGTNGAYGAYYTNGAYAARYTNMGNAARTTYCAYGCNAAY GARTTYAAYCARYTNCARYTNGARAARTTYGARCARYTNCARCARGAYMGNYTNTAYAAY TTYTAYAARYTNAAYMGNAARCAYGARAARGARAARGCNGCNCARYTNCARACNATGGAY AARTCNACN---AAYGCNGARTTYATHAARGTNTAYCAYGAYYTNATGATGMGNCARCAY ATGGARAARGARGCNYTNTCNGGNGAYYTNGAYATGAAYGARGTNCARGARATGCAYACN YTNAARGAYGARMGNAAYAARAARGARTCNAARGCNATGGAYCARYTNTCNGARAARYTN GTNGARCARATHGARGGNACNTCNAAYATHACNTCNAARGAYGCNGCNAARYTNATGAAR YTNCAYAARGCNCARATGGAYCARTAYAARGCNAARACNCARMGNGAYAARCARGCNATG YTNGCNMGNYTNCARGARAARYTNCARCARMGNATHGARGCNGCNGAYGARGCNGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARGTNAAYTTYGTNAAYAARGARCCNAARGAYYTNATGGTNGGN GCNGARAAYGTNCAYTTYCARTGYCAYYTNAAYAARGGNGCNGTNTAYYTNYTNAAYGGN GTNGTNAAYATHATH------------------MGNGTNAAYCCNGTNAAYYTNGARGAR ACNGTNYTNACNACNAAYGGNCARTAYGARGGNGAYGAYCCNAAYAAYTAYAGYGTN--- GAYYTNAARGTNGCNGAYAARGGNYTNGAYYTNGAYTTY------MGNATHAAYAARATH MGNGAYATHGAYGAYGGNAARTAYATHTGYAARGTNACNAARGARGGNGCNGGNMGNACN GAR------------------AARGARGTNATHATHCAYMGNCCNATHGAYGCNYTNAAR YTNAARATHGGNAAYTTYGARCCNATHATGGARAGYATG---------AARGGNCCN--- ------YTNGAYCCNGAYACNTAYAAYGTNTCNTGYGTNGCNGARGGNAGYAAYCCNGCN ACNGARCAYGTNCAYYTNTTYYTNGAYGGNGARAARATHCCN---CAYAGYGARCCNGCN ATHGARGCNATGAARACNCCNYTNMGNAARTTYMGNACNACNATHTTYGCNATGGTNGAY ATHATGGTNAARAAYGCNGGNCARGARATHCARTGY------CARGCNGARGAYTCNTCN AARAAYTCNAARACNTCNAARATHACNYTNAGYGTNAAYACNTAYGAYCCNGARGTNACN TGYAAYGAYACNCAYGCNTAYATHGGNGARATGAAYCCNGTNYTNGTNTGYMGNGTNAAY CAYTCNGARGTNGARGTNACNGGNTAYGCNTTYCARATGGGNGCNTCNGGNGARATHATH MGNCARGGNGCNGCNCAYTCNAARAAYATHAARGTNATGGTN---------GARGAYGTN TCNCCNGGNATHTCNGAYGTNACNYTNGAYYTNCAYAARGCNGARCAYTCNTAYYTNGAY AARCAYTAYTAYYTNYTNGTNGAYATHAARGGNGGNCAYACNAGYAARGCNAGYGTNMGN YTNCAYAARACNGAYGCNCCNGAR------------------------------------ ---------GGNAAYGCNTCNYTNACNTGYCCNGTNGGNACNGTNATHAGYYTNTCNGAY GCNGTNGTNGGNMGNAAYGAYTGGTCNAARTGYTTYYTNACNAARAAYGAYTGYTTYCAY TCNACNMGNATHTTYGAYAAYTGYGAYGGNAARACNGTNTGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CCNGAYTAYTAYYTNTCNYTNYTNCAYAAR AAYYTNATHGARGGNCCNGTNTTYAAYGCNACNGTNAARCCNTTYACNAARTAYYTNMGN GTNTAYGCNCAYTGYACNMGNAGYTCN---GARYTNTAYAARAARGGNGCNGTNACNTAY GCNTAYYTNAAYGTNAARAAYGARTCNACNGCNGTNAGYTTYGGNCARTTYTTYGAYYTN CARTAYGAYYTNTAYATHYTNACNCCNGGNGAYTCNGAYGGNYTNAARTCNMGNTAYGTN AARYTNAAYGGNGARGTNYTNAARATGTCNGGNACNTCNYTNCCNGARYTNAARCCNAAR CCNCAYAARGGNTTYGTNAAYGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNGTNGAYMGNATHGARAARGGN CCNTAYGGNGGNCCNCCNMGNAARATHTCNATHGCNGGNATHGARCAYGARATHAGYTTY CARTTYCCNCCNMGNMGNATHCARATHGAYGGNGTNTCNTGYGCNYTNAAYYTNGAYAGY AARATHCCNTAYGTNGTNATHGARGGNAARCCNTTYGGNATHMGNTTYGAYGGNGARCCN AARGTNATHTAYATHAAYGARCARCCNTTYGTNATHCCNTTYGAYMGNGCNACNAARATH MGNYTNGGNGCNMGNCCNATGTAYATHGCNTTYGGNGGNCCNGCNCAYGARATHATHATH GAYGGNAARTGGTTYGARGTNCAYTTYAAYGAYACNCCNAARGAYATHCAYYTNGGNAAY MGNCAYTTYAARATHMGNATHCCNGGNCCNCCNCCNMGNGTNAARATHYTNAAYCARATG CCNCCNAAYTTYGAYACNTCNMGNYTNATGACNGGNCAYAARGARGTNCCNAAR------ CARACNCCN--------------------------------------------------- ---------CCNACNCCNGGNGCNGCNCARCCNGCNMGNCCNACNGTNGAYYTNMGNGGN GCNGGNACNACNATGAAYGARACNGTNYTNAARTCNYTNATHYTNYTNGCNAARYTNAAY AAYGTNGCNYTN---------CCNGAYAAYTTYCAYAGYYTNCCNCCNCCNATGCARGGN GCNYTNYTNCARMGNYTNYTNAARYTNAAYYTNTCNTCNCARMGNGCNTCNYTNCCNCAR GGNCARYTNAARACNMGNYTNGCNCARYTNGGNTCNTCNYTNAAYCARATGMGNCARCCN CCNATGAAYCARYTNAAYCARCCNCCNATGTCNAAYCARYTNAAY--------------- CARCCNCCNYTNTCNAAYGCNCCNGARGGNMGNCCNGGNGCNCCNCARCCNGGNCCNTCN GCNTCN------AAYATHCARAGYGAYGCNACNYTNATHGGNCCNGARGCNATHGCNGAY ATHGTNAARMGNATHCARCARCARAAYCCNTCNTCNGGNCCNGTNATGATGAAYCARCCN YTNGAYTCNTCNYTNATGCCNAAYATHTCNCARACNACNGCNCCNCAYACNGTNTTYMGN GCNCARCCNYTNGCNAGY------------CAYCARCCNMGNCCNCCNATGAAYCAYCAR CCNMGNCCNCCNATHACNAAYCAYCARATHACNCAYCCNATGGGNCAYYTNCAYYTNCCN ACNCAYATGAGYCAYCARCARACNCCNCCNGGNATGAAYAAYCARCCNCCNATHACNAGY CAYCARCARCCNCCNATGATGAAYAAYCARCCNCCNCCNATHACNAGYCAYCARCCNMGN CCNCCNATHACNAGYCAYCARCCNACNCCNATGATGAGYAGYTCNGCNAAYAAYTCNAGY GCNACNTCNTCNAGYTCNTCNGCNYTNGAYATHAAYTCNYTNYTNAAYAAYYTNYTNAAR GCNGGNYTNATHAARGAYCCNGGNACNGGNGARCCNGCNCCNGCNCCNGCNCCNGTN--- ------------------------AARCCNGARCCNGARGCNCCNAGYATHACNACNGAR CCNTGGCCNGTNAARAARGARGTNGCNATHCCNGAYYTNACNAGYTTYGAYCCNAARAAR YTNAARATHATHCAYAARGCNGTNGTNAAYGARYTNCAYAARGGNATGCARTGYCAYACN TGYTCNGCNMGNTTYACNGAYGARGAYCARGARAARTAYMGNGCNCAYYTNGAYTGGCAY TTYMGNCARAAYAARYTNGARCARGARATGGTNAARGTNGCNMGNAAYMGNAARTGGTAY TAYACNATHCCNGAYTGGATHCARTAYGARGARYTNGARGAYYTNGARGARAARTCNMGN AGYGCNATHTTYGAYCARATGMGNTTYGGNTCNGARCARTCNAGYTCNGGNAGYYTNAGY GTNGAYGTNYTNAARYTNCARGCNYTNGARGGNAARGAYGTNGTNCARAAYCCNGTNGCN TCNGGNGTNGARGGNGARGAYGTNTGYGCNACNTGYMGNGAYCCNTTYGAYCARATGTGG AAYGARGARACNGARGARTGGATHYTNAARAAYACNATHAARGTNGAYGGNAARACNTAY CAYCCNATHTGYTAYGARGAYYTNCARGARACNCCNACNCCNGCNGCNGAYATHGTNCAR AAYCCNYTNACNCARGARYTNGCNGCNYTNAARGARGAR---ACNGAYGCNCCNCARYTN ACN---------------AGYGTNAARGARGARACNGARGAYAGYYTNGAYYTNACNAGY AARGTNGARATHMGNGARAGYGTNAARCARGARATHAARATGGARGTNGARGAY------ ------------------------CCNGAYGCNCARCAYGCNCARCCNATHGGNGGNAGY AAYGTNTCNGAYCAYGCNACNTCNCAYGCNGAYGCNGTNGTNAARGGNGARTAYACNGAR GTNAGYGAYGARACNGCNGCNATGTCNTAYACNACNGCNCCNATHCCNCCN--------- ------------------GAYCCNGAYATHAARTGGGARATGGAYTCNAAYCCNACNCCN GARGTNTCNMGNACNCCNAGYCCN------------------------------------ ---------TAYCARTGYCCNYTNTGYAGYGTNACNTAYTCNMGNMGNCAYCARATGGCN TTYCAYATHYTNAARCAY---CCNGARYTNYTNACNTGYTGYGTNYTNTGYCAYYTNGAR TTYGARTCNACNTCNGAYYTNCAYACNCAYGTNMGNTCNCAYYTNGARGARAARGAYTTY TCNTGYGARAARTGYGGNGARMGNTTYTTYACNTAYACNAARYTNTAYGARCAYAARAAR TCNCAYAAYAAYACNAARGAYTTYTCNTGYTCNATHTGYGGNGARGTNTAYGCNCARMGN MGNAAYYTNGARTTYCAYAARAARTCNAARCAYGGNACNGTNYTNTAYAARTGYGARGTN TGYGARAARGARTTYMGNTGYAARCCNGTNTAYGAYMGNCAYYTNAARATHCAYTCNGGN ATHMGNCCNTAYAARTGYACNYTNTGYGCNAARGAYTTYATHAARMGNTGYGCNYTNACN TCNCAYATGTGGACNCAYATGTCNCARAARMGNTTYAARTGYGAYCARTGYGAY------ ------------------------------------------GARGARGAYGAYGAYTCN GAYGGNCCNGARTTYACNGARGARGARATHAARAAYGAYCCNAARAARMGNATHYTNTGG GCNTCNGARAAYAAYAARATHGAYGCNGTNGARGARYTNYTNAARAGYGAYCCNGGNYTN GTNAAYGTNGCNGAYAGYGAYGGNTAYACNCCNYTNCAYMGNTGYTCNTAYAAYAAYCAY CCNCARGTNGCNAARATHYTNATHAGYTAYCARGCNAAYATHCAYGCNMGNACNGTNGAY GGNTGGCARCCNYTNCAYAGYGCNGCNMGNTGGAAYTCNGTNGARACNGCNCARYTNYTN ATHGAYTGYGGNTCNGAYGTNAAYGCNCARACNAAYGGNGGNYTNTCNCCNYTNCAYATG GCNACNGCNGAYMGNGGNCAYCAYAARATGYTNGARYTNYTNYTNAAYATHCCNACNATH AAYACNAARYTNATGTCNMGNGCNGGNGARACNGCNGARGARYTNATHGCNMGNAGYAGY TGYCAYTAY---YTNYTNGARYTNMGNGGNAARAGYGTNAAYAAYYTNAAYAARGCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARAARGARMGNGCNGARTTYGARAAYMGN ATHAARAAYCARGCNCARYTNTTYGARAAYTCNAGYCARAGYGARGAYAAYYTNYTNAAR MGNCARYTNGTNGAYYTNAARAARACNACNGCNGAYCARAGYGTNGTNATHYTNAAYCAR GARMGNCARATHTCNGAYYTNYTNGCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TGYCCNTGYTGYATHTGYCAYGAR AAYYTNYTNAARYTNCARTCNYTNYTNTGYTCNACNCAYATGACNGAYTCNYTNGCNTAY MGNATHYTNGARYTNYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CAYTCNTCNTCNGCNGGNGCNCARTCNCARTCNTCNACNGTNTCNGGNYTN AGYGGNGCNCCNATHAGYAAYCCNAGYTCNTCNCCNMGNCCNAGYATHYTNMGNAARMGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNAAYYTNACNMGNTGYTCNCAYYTNACN AAYAARTGYYTNCCNGTNYTNTCNAARMGNYTNCCNTAYYTNAARTCNYTNTAYATGGCN GGNGTNCCNTCNATHACNCCNCARGCNGTNCARGTNTTYYTNGARGAYTCNAARAAYATH AARYTNYTNGAYGTNTAYTTYATGAARTCNACNCCNGARGARTTYAARTCNYTNMGNCAR YTNGCNACNAARCAYTGYGTNGAYYTNATGYTNCARCCNCCN------------------ GGNAARGAYAAYGCNGARGAYGTNTGYGARTCNGARGARGARGARGARGAYYTNYTNGCN TAYGGNGAYGAYAAYGAYGAYGAYGAYGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CAYCAYCAYCAYCAYAAYAAYCAYCAYCAYCAR CAYCCNAAYCARCAYCARMGNGGNCARGGNATGMGNCAYGGN------------GGNMGN GGNGGNGGNGGNCAYMGNATGGAYAAYCAYGARMGNGCNMGNACNGAYGAYCARMGNAAY GAYMGNAAYGGNGGNCARTCNTTYGTNMGNGGNMGNGGNAAYGGNMGNGGNCARATGAAR GARGGNGGNGCNATGMGNGGNTCNCARGGNCAYCCNMGN------CAYMGNGGNMGNGGN GGNMGNTCNTCNGARCCNYTNAARTTYGAYACNGAYTTYGAYTTYGARACNTCNAAYGCN CARTTYGAYAARGAYGAYATHGARAARGARYTNAARAAYYTNACNYTNAGYGAYAARCCN GTNAAYGGNGAYAARGCNGARGARGAYCCNGAYATHGARGARGARGARGARGARGARGAR GARGARGAYYTNGTNTAYTAYGAYAARAARAARTCNTTYTTYGAYAAYATHAGYTGYGAR GCNACNGARAARGCNMGNGGNCCNMGNCCNAAYTGGMGNGARGARMGNAARYTNAAYAGY GARACNTTYGGNATHTCNGARAAYTAYMGNMGNAAYTAYMGNGGNMGNGGNAAYTGGMGN GGNAAYAAY---MGNGGNGGNTGGMGNGGNGGNMGNTAYMGNGGNGGNTAYAAYMGNGAY GGNGGNTAYTAY---GGNAAYMGNGGNGGNGGNGGNMGNMGNCCNGARTGGGAYTAYGGN GAYMGNMGNMGNATGGARGGNCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYTAYCCNGTNGAYGTNGARGTNTCN CAYGAYGARTTYAARTTYGTNGARMGNYTNYTNCCNCARCARACNGTNCCNGAYGTNCCN TCNCAYTCNTCNTAYCCNACNCCNTCNGGNTGGTTYCCNCCNAAYGAYGARATHMGNTCN CARCARCCNTAYYTNGTNMGNMGNACNAARAAYCAYGTNYTNCCNGTNTAYCCNGCNCAR MGNGARGCNTGGGGNMGNATGYTNCAYCAYGTNGTNATHAARAAYATHGAYGGNGAYATH TGGGCNATGGARTCNGARYTNTGYMGNTTYYTNAARGARAARACNGGNGARGARAAYATH ATHACNCARGTNCAYGARGTNAGYCARTGYATHMGNGTNMGNGGNCARCAYMGNGCNYTN ATHGCNGAYTTYYTNYTNGARAARGGNATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGTAYTTY GGNTCNAARTTYGTNTAYYTNGGNAAYGAYCARGARGAYGARGARGARGTNAARGTNTCN GARCARGAYGAYGTNGTNYTNTCNGAYAGYGAYGTNAGYGAYGAYGAYGGNGARACNTGY YTNYTNGAYATHYTNGAYACNGCNGGNCARGARGARTAYTCNTCNATGAARGAYCARTAY GTNMGNAGYGGNGAYGGNTTYGTNATHATHTAYAGYGTNACNGAYGGNGARAGYTTYAAR GARGCNGARGCNATHTAYMGNTGGYTNAARMGNATHMGN---GARGAYGARAGYCAYGCN ATHYTNGTNGCNAAYAARCARGAYYTN------ACNGAYGARGCNGTNATHACNGCNGAR ACNGGNAARGARYTNGCNGGNAARYTNGGNATHTCNTTYTAYGARACNTCNGCNAARACN GGNACNGGNATHGAYAAYGCNATGAARAGYYTNATHMGNYTNATHCCNMGNAARGGNAAY GAYTAYAARATHGTNATGYTNGGNAGYGGNGCNGTNGGNAARTCNAGYATHACNYTNMGN TTYGTNAAYAAYACNTTYYTNGARGAYTAYGAYCCNACNATHGARGAYTCNTAYMGNAAR ATGATHACNGTNAAYGGNYTNAGYGCNGTNAGYAARGAYAGYAARAARGCNGTNAARAAR GCNAARAARYTNAARAARMGNACNACNTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY AARCCNCCNAARMGNCCNAAYGTNGCNAARGAYTTYYTNGGNMGNMGNGCNACNGTNGGN GARATHYTNAAYCARCARMGNCCNACNYTNAGYGCNGGNGARTGGMGNCARCAYTTYAAR AARACNMGNCAYAGYCCNGTNTCNACNACNGCNAARCARGCNGCNGTNYTNGARGCNAAR AARMGNATHAAYGAYGTNCARMGNGCNGGNGTNGTNGARAARGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGNAARMGNTCNYTNGTNGAYATGCCNGTNGTNACNACN YTNTAYTAYTGYTCNYTNTAYCAYTAYCAYYTNGCNGARAAYTCNYTNGGNAGYCCNCAR GCNYTNACNAARMGNCAYCARATHTCNGARAARCARTTYGCNTGGACNGCNGTNAGYGCN MGNGCNAARYTNAARCARTGGAARGAYGTNGARACNATHYTNACNGCNAARGGNTGGTTY GGNGGNTCNAARATHAARGCNGTNATHGCNTTYGAYAARATHGTNGGNATHYTNTAYMGN AAYAAYGCNCCNCCNGAYATHYTNGAYAARTAYYTNGCNATGATHTCNGAYYTNGARYTN MGNYTNAAYYTNGCNAARAARGTNGTNTGYCAYAARGCNGTNGTNGAYACNTAYGCNGCN YTNAARGAYMGNGCNTCNYTNGARGCNTAYGCNTCNAARYTNGAYMGNTAYTCNAARGAY GGNYTNTAYGCNYTNGAYATGYTNAAYGGNTCNYTNGTNAARTGGMGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TCNAAYAGYACNCARGAYACNAGYTCNTCNGCNGCNTCNCCNTCN TCNGTNCCNGAYTTYAAYATGGARGCNGAR---GGNAAYATHCCNACNACNGAYCCNGCN AARTGGACNGTNACNGAYGTNTAYGAYTTYGTNYTNGCNYTNCCNGGNTGYTCNGARTAY GCNGARGAYTTYMGNTCNCARGARATHGAYGGNCARGCNYTNYTNYTNYTNAARGARGAY CAYYTNATG--------------------------------------------------- ---------------------------ATHCAYACNACNTCNATGTCNCARGTNGAYCAY MGNAARGARMGNGCNATHGTNAARCAYYTNTAYTAYMGNAAYCAYGARAARACNYTNAAR CAYTCNTAYAGYCCNATHGTNGARYTNCCNGAYTAYACNTAYYTNGAYGGNMGNCCNACN GARATGACNAARTCNTAYAARGARAARCARGARMGNAAYCAYCAYYTNGCNGARCARGTN GTNAARYTNGTNGAYGARGTNAARTTYGCNCARAAYGARTTYYTNMGNAAYMGNGAYACN ACNGTNCAYGARCARGARAARMGNMGNGARTCNMGNYTNAARGARAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGTCNTTYGAYYTNGTNTCNAARTGYYTNGARATG------------GARGAYYTNGGN GARACNTCNAARAAYAARAARAARMGNAARTAYAARACNAAYGAYGCNATGCARATHATH AARACNGAYMGNCARGGNGTNTGGAARGARYTNAARAARATHMGNAARAARCARGTNAAR GAYATHAARGTNAARMGNAARATGGARAARTTYAARTCNGCNATHGARATHTAYAARGAY GARCAYGGNTAYGAYAAYACNGAYMGNAAYGTNGARACNYTNYTNAARATHTCNCARYTN GGNAARGTNGCNGARAARGAYGCNGARAARATHYTNAAYGARATGCCNTGYMGNYTNTCN MGNGAYYTNAARGARGARGTNAARGARCCNGARCCNGTNTCNGCNTTYACNGARGARGAY TTYGARAAYTTYGCNAARGARTAY---------ATGTCNATGCCNCAY------GCNCCN CCNATHGGNGGNGGNAAYCAR---CAR---------------------GAYTCNCARAAY MGNAAR---YTNYTNAARCAYATHGARGARCARAARMGNAARYTNTCNCAYGGNCAYCAY TCNTCNTCNYTNAGYATH---CCNGCNTCNATGAGYGGNAGYCCNACNGCNATGYTNAAY AAYCCNCCNTCN---GTNCCNGGNYTNTCNGCNGCNGARTAYGCNACNATHAGYAAYCCN CARCARMGNACNGCNYTNCARCARGCNCAYGCNAAYTCNGTNGGNTAYTTYATHCCNCAR GAYTCNTCNTTYGGNAAYYTNATHYTNCCNGTNYTNCCNMGNYTNCCNGAYGCNAARACN GARACNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARMGNATGMGNCARGARGARGARMGNYTNGCNGARGARMGN MGNCARCARGARGARGARGARGARCARMGNAARYTNGARGARGARACNATHMGNYTNGCN GARGARGCNMGNAARGCNGARCARGARMGNYTNGARAARGCNATHGARGCNGARGARAAR MGNMGNAARGARGARGCNGARMGNYTNGARCARGARMGNAARGCNAARGARGARGCNGAY MGNAARGCNAARGARGARGCNGARMGNYTNGARAARGARAARCARGARAARGCNAARAAR GAYGARGARGARMGNYTNGARMGNAARAARAARYTNGARATGATHATGAARMGNGTNAAR ACNGAYCCNTCNACNAAYGAYAGY------------------AGYAGYTCNYTNAARACN GARAGYCCNACNAARTCNTCNGGNAGYTCNCCNAAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNCARGTNYTNGARTCNCARTCNCCNTGGMGN YTNTCNTTYATHACNGAYYTNATHTGGGGNTTYATHAAYTTYATHGTNYTNTTYTTYCAR ACNYTNTTYAAYCCNAGYAARAAYAGYMGNGGNGAYAAYTAYTCNACNGAYTAYMGNAAR CCNGGNGGNGGNGGNCCNCCNACNMGNMGNATGGGNGGNTTY---MGNMGNGGNGGNGGN GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TTYGAYAGYTCNCCNGGNTAYAAR ACNTGYGCNGARATHTGYTAYACNGAYGGNTGYAAYTCNGCNTCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTNACNTCNTCNYTNTAYCCN AAYACNGTNCAYTCNGARGGNATHYTNAAYCARATHTTYCARCAYCARAAYAARAAYMGN ACNMGNCCNTGYYTNCARGGNMGNACNGAYYTNTTYMGNATHYTNAARTAYGAYATHAAY ACNGCNGGNAAYGGNTCNGAYCAYACNCARCCNYTNYTNYTNACNMGNCAYAAYGTNGTN CCNGGNATGTTYYTNATHTAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARTGGGTNYTNTTYMGNTTYCCNAARGGNGARAAR ACNCCNYTNGARGARYTNYTNTTYAARYTNGTNGARTAYGTNGTNYTNTTYACNATGGCN GCNGTNATHTTYGARGCNCARTGGMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CARAARGCN TGYYTNCARYTNGAYCARCARGCNGGNYTNYTNGARCCNCCNGARCCNTTYTTYTGGCCN GCNAAYAGYYTNCCNAGYATGAARAARGARGARAGYGAYGARGARGTNGARGAYGARYTN GAYGAYAARYTNCAYGCNCAYTCNTCNGAYGAYGAYGTNGARGARGAYGCNGARGARCCN GCNTAYYTNAAYTTYAGYGTNTTYGARMGNACNGAYATHYTNACNMGNTAYYTNMGNAAY GTNTAYAARTAYTGYATHTGGTGYGGNGCNMGNTTYGAYGAYGARGAYCARATGAARTCN ATGTGYCCNGGNAAYTCNGCNGARGCNCAYGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GCNTTYTTYAARMGNATH TCNGGNATGCAYTGYACNGTNCCNGARACNGCNACNAAYTGGAAYYTNTGYTAYGAYYTN YTNYTNCARTCNYTNGAYGGNTAYTCNYTNTCNGTNGAYCCNGCNCARATGAGYMGNGCN CARCCNAARGGNTGGCCNGCNYTNCARTAYMGNGTNYTNCAYGARYTNGTNTTYGCNGCN MGNMGNAGYGGNACNCCNCARGTNGCNGTNMGNCAYATGAGYYTNYTNGTNCAYMGNATG YTNCCNTCNYTNTCNGTNGCNGARCARMGNGARGTNYTNGCNGGNYTNTCNACNYTNACN GCNMGNAAYCCNGGNCAYCCNAARTCNATGGCNYTNCCNAGYGGNYTNATHYTNCCNCCN GTNGCNYTNAAYTCNYTNCCNCARYTNAARTGYYTNAARYTNGTNCCNCCNACNCCNGAY YTNMGNCCNCAYMGNYTNGARGGN---GTNTCNAGYGAYAGYTCNGGNGTNTTYATHTAY ACNCCNYTNTCNYTNGCNACNAGYMGNACNGAYGAYAGYMGNCCNGAYTTYAARTGGGTN TGYGGNGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GTNTCNGAYGTNTTYGAYACNTCNGCNGGNAAYYTNACNGCN AARCARATHYTNCAYGTNGTNATHCCNAAYTGGTCNGARTAYAGYAAYAARGAY---AAR TGYAARACNGAYYTNMGNACNTCNYTNATHAAYTGYYTNGCNACNGCNGARAARYTNCAR TGYMGNTCNATHGCNYTNACNGCNATHGGNTCNGGNCAYYTNGGNGTNCCNYTNGARGTN TGYGTNGAYTGYTAYYTNAARGCNGTNMGNYTNTTYGARTCNATGCARTTYTCNTTYTTY YTNAARGARGTNCAYTTYGTNGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGAYCAYGARTAYGGNATHCARGTN ACNAAYAARTTYGCNYTNTTYACNGGNAARGARGGNGAYCCNYTNAAR------------ ---------------TCNTCNAAYAARAARAARAARGGNAARTCNAARYTNGARGARTCN GARGTNAARGTNGCN---------GTNCCNGARAAYGARGTNCCNAAR------------ AARAARGAR---------GAYAARCCNGTN---GTNAARCCNAGYGAYGGNGGNMGNGGN AGYGCNMGNAAYAARGARTCNAARGARYTNMGNGARGCNGAYGGNGAYAARMGNCCNCCN MGNMGNCARGGN------------------------------------------------ ------CCNAARGAYTTYAARGAYGCNAARCAYGGNGAYGARAAYGTNCCNCCNGARAAR ACNGAR---GGN---GGN---GGNTTYMGNMGNMGNGAR---------GAYMGNGAYGGN GGNTTYAGY---------------GARMGNGGNMGNGGNMGNGGNMGNGGNGAYMGNGGN MGNGGNMGNGGNGGNGAYMGNGGN---GGNAGYTCNGGNGGNTTYGGNCCNMGNGGNGAY MGNAARMGNGARTTYGAYMGNCAYAGYGGNACNGAYMGNACNGGNATHAARTCNGTNGAR AARAARGAYGGNGGNGGNGCNCAYAAYTGGGGNAAYTTYAARGAYGAYYTNGARGARCAR GGNCARGTNAAY---YTNGAYGARTCNGCNGAYGCNGGNAGYCCNCARGARAARACNGTN ------------YTNAAYGARAGYGGNGARGTNGARAAYCCNTCNGARGARGARGTNCAR CCNCARCARATGACNYTNGAYGARTGGAARGCNYTNMGNGGNCARCAR---AARGCNAAR CCNGGNTTYAAYACNMGNCARGCNGGNGARGGNGTNGAYTCNTCNCARTGGAARGAYGGN GTNGARTAYCARAARAAR---------GTNGARTCNGAYCAYGARGARGAYGARAAYGAR CAYGAYCAYGAYCAYCAYCAYMGNAGYAGY---AAYAARCARYTNGTNACNGAYATHMGN ATHACNTTYAAYGAYAAYCCNMGNMGNGGNMGNGGNMGN---MGNGGNGGNMGNGGNGGN ATGGARMGNGGNGGNGGNATGGAYMGNGGNGGNMGNGGNMGNGGNGGNMGNGGNGGNGGN GGNTCNMGNGGNMGNGGNGGNGCNACNAARGAYGCNGCNCCNMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TGGTCNAGYTCNGGNCAYAARYTNGGNTCNTCNAGYCAYMGN CCNTTYCCNCCNTCNTTYCARAAYCCNTCNGAYAARGCNTTYAARAAYTCNYTNTCNMGN AARCARAAYCCNTCNCCNTTYGAYTAYGAYATGAAYGAYTTY---TCNTCNAARAGYTTY TTYATHATHGGNATHAGYGGNACNACNAAYAGYGGNAARTCNAGYACNGCNTCNMGNYTN TCNAARGTNYTNCCNAAYTCNGCNTGGATGTGYCARGAYCAYTAYTTYYTNACNGCNGAY GAYCCNMGNGTNGARGTNGARCCNAAYGGNATGCARAAYTGGGARAARYTNAGYTCNYTN GAYATGGARACNATGGTNAGYGAYGTNTTYGCNTGGATHAAYAARTAYTCNTCNGGNCAY CCNCAR------GCNTTYYTNATHGTNGARGGNTTYACNATHTTYAAYTAYCARCCNYTN GCNAAYYTNTTYGAYAARAARTTYTTYATHCARGTNGAYMGNGAYACNTCNGCNGARMGN MGNGTNCAYMGNACNTAYGAYCCNCCNGAYGGNCCNGGNTAYTTYGAYGARGTNGTNTGG CCNATGTAYGTNAARAAYYTNAARGAYYTNGARGAYCAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATHCARGARGCNYTNGARMGNCAYCAR GCNTTYGCNCARCCNGCNATGYTNGAYAAYATGGARGGNYTNACNTAYYTNGAYYTNMGN YTNGAYTTYMGNACNAARAARCARACNAARTTYATGAARAAYATHMGNTCNACNYTNYTN YTNCCNCAYCCNTTYACNTGGGGNCCNCCNCCNTCNATHYTNGTNTTYTGYAARGARGAR GARCAYACNAAYATGGCNYTNTCNYTNGGNGCNAARCAYGCNGGNTCNCCNTCNGARGTN ATHAARATGATHGARAAYGGNGTNYTNAAYCCNAARGAYTTYGARCAYGTNYTNGCNACN GCNGAYTGYACNACNGAYATHACNCCNGCNMGNTCNTAYTTYMGNGAYAARTTYCCNCAR MGNGCNAARGGNAAYYTNGGNCCNGAYYTNGCNTCNATGTGGAARYTNTTYTAYGARGGN TAYACNTAYGARTCNCAYAAYYTNACNGAYGCNCARGGNAARYTNCARGTNCCNYTNGGN CARYTNAARCARCCNGTNGAYGARYTNGTNTCNAAYTTYGARGCNTAYATHGARTCNGTN AGYAARCAYMGNAGYATHGCNYTNGGNCCNTTYATHCARTCNATHAARGTNYTNGCNCCN CCNTCNCCNGARGARTTYATHGTNMGNGTNGARGAYTAYGTNCCNGGNTAYAARAAYGAR GARGTNGAYTCNGAYGAYGARGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARAARTCNGTNGARYTNTTYTAYGAYGTNGTNTCNCCNTAYTCNTGGTTYGCN TTYGARGTNATGTGYMGNTAYCARAGYMGNTGGAAYATHAAYYTNAARYTNMGNCCNTTY TTYYTNGGNGCNGTNATGAARAGYACNGGNAAYMGNCCNCCNGCNATGGTNCCNAAYAAR GGNMGNCAYAGYATGGTNGAYGTNGTNMGNTGYGCNMGNTAYTGYGAYGTNCCNTTYAAR ATHCCNAARAAYCCNGCNGARYTNATGTTYGARAARGGNAGYYTNAARGCNCARMGNTTY YTNACNGCNYTNGAYATGAARTGYCCNCARAARGTNGARGCNGTNTCNMGNGARTTYTGG ATGMGNGGNTGGAGYMGNGAYGARGAYYTNTCNGARGAYTCNAGYATHGCNGARGCNGCN ACNAARGCNGGNYTNAGYCARAARGAYATHCARGARYTNYTNGCNYTNGTNAARGARCCN CARGTNAARGAYMGNYTNAARAGYGTNACNGARGARGCNYTNGARYTNGGNGCNTTYGGN TCNCCNATGATHGTNGCNGAYGTNGGNGGNAARAARGARTGGGTNTTYGGNAGYGAYMGN TTYCCNATHYTNGCNGAYATHYTNGGNAARGTNCAYAAYGGNATGTGGAARYTNTGYACN TCNAAYAARAARCCNGAYAGYGAYTGYATGAAYTGG------------------------ ---GCNGAYATHAARAAYATHGGNGAYTGGYTNAARGCNGTNCARGCNATGGCNATHYTN GGNYTNATHTTYGCNGTNYTNTGYTGYGTNYTNTCNYTNGTNGGNYTNATHCARGARAGY MGNGGNGAYMGNAARMGNTTYATGCCNATHGCNATHAGYATHTCNGGNATHYTNGGNGCN ATHTTYATHYTNATHGGNGCNATHATHATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TGGAARYTNYTNGCNGAYCARTAYACNAARACNACNAAYGTN GCNMGNGTNATGGTNGTNGCNGTNTTYGCNYTNGCNGTNATHTAYMGNGAYGARATHCAR ACNCAYATHGAYGAYYTNTGGGCNCAYYTNMGNGARGAYTCNTTYTTYCARTCNGCNCAY TAYGARACNGTNTAYGTNACNGTNGTNTAYGTNTTYYTNATGATHTTYTAYCCNTAYGTN ATGYTNCAYATHCCNTTYTTYYTNAARTTYAARGTNTCNGARGARATHMGNTAYGTNAAY CARACNATHYTNGGNATGGCNATHGAYYTNGTNTTYCAYATHGCNCCNYTNYTNGTNGCN GAYATGATHATHATHAARMGNTAYCCNGGNGTNCCNTAYTCNGAYATHGARCCNYTNAAR CARGAYTGGATHGTNMGNAARMGNCCNYTNCCNGARGCNGCNCCNGGNYTNTTYGARATG TGYTTYCARGTNGCNGGNAGYGTNTTYYTNTTYGAYTTYTTYTTYACNGCNGTNCAYTAY GCNYTNCAYMGNGAYMGNYTNYTNTAYAARTAYTTYCAYGCNAARCAYCAYGAYCAYGAR ATHGTNCAYGCNCAYGTNACNAAYCARYTNTCNGTNGTNGARMGNGCNYTNCARGTNATH TCNGCNAAYTAYGCNYTNAARGCNTTYMGNAGYCAYCCNYTNTCNMGNYTNGTNTTYGTN CCNGTNTTYYTNTGGATGYTNATHGAYAAYCAYACNGGNATHGAYYTNCCNTGGGGNCCN CAYMGNYTNATHCCNGGNAARGTNATGGGNGGNCCNGCNAARCAYCAYGCNCAYCAYGTN CARGGNCAYGGNCAYTAYCARCCNTTYTTYAAYTAYYTNGAYGAYTGGYTNGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AARCCNTCNTCNTCNMGNAAYTGYCAYACNATH--- ---------GAYGARGARGAYGAYGARYTNCCNGAYATHCCNTTYGAYATHCCNCARAAR AGYAARGARGCNAAYTCNAGYTAYGTNTCNTCNCCNCCNYTNCARGTNTCNTGYCCNGTN TGYYTNGAYGAYYTNAARGARGTNAARAARAGYCARMGNMGNATGATGTCNACNGTNTGY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MGNATGACNCAR GARTTYYTNAAYTTYGCNGGNATGCAYGAYTGYGAYATHCCNTCNTAYTGGAARGCNAAR AAYGAYAAYGCNAAYCARACNGAYTTYTCNYTNGTNCCNGTNAAYAARAARACNAGYAAY GCNATHAARMGNATHTGYGARACNACNTGGAAYGARAAYYTNACNGGNCAYGGNCARGAY GCNACNAAYATHACNCAYTCN---AARATHMGNGTNGTNAARGTNGARMGNYTNGARAAY YTNGARYTNTTYTCNAARTAYGTNCAYCAYMGNCARTCNGTNTTYAARGAYATGGAYMGN MGNAARMGNYTNTGYAARGAYGTNGGNAARYTNAAR---AAYAGYAARGGNCCNGTNGAR ACNGCNAGYGTNATHCCNYTNTTYATGAARAARGAR---YTNTAYAGYGARATHAAYGAR GTNYTNYTNTTYCAYGGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TTYGARCARAAYYTNGGNGAR TTYATGYTNACNGTNAARCARATHYTNCCNAAYTCNACNCARACNATHAARAAYYTNAAR GARTTYCAYACNAAYGTNAARATGGCNAARGGNYTNAARAARGTNCCNTTYAARAGYATH GAYTTYTAYYTNCARTCNYTNGAYTAYTTYAARAARGTNTTYCARGAYGTNGARMGNGAR ATHATHCAYCCNYTNTGYCARGTNCARGCNGTNTGYGARAAYGARAARCARMGNAAYYTN AARTCNACNATGAARMGNGCNTGYTAYGARATGATHGCNCAYYTNGCNGTNGARGCNGAY YTNCARAARATHMGNCAYAARGARTGGGARAGYAARGTNYTNYTNMGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNCCNATHGGNAARAARYTNATGATHCCNAARCARYTNGGNTGYATGYTNACNACN GARAGYYTNTCNYTNATHAARTCNAAYGARMGNATHGAYMGNAAYCARMGNYTNTGGGAR GAYGGNGARGTNGCNTCNTCNAARAGYGGNAAYTCNGCNCCNGAYGAYAGYGGNTCNGAY GAYGAYGGNGGNTAYYTNTCNGARACNGGNTCNATHCAYTCNGAYCARGARGCNTGGAAR GCNACNTCNTCNAARCAYAARAAR------AARCAYAARCAYAARAARAARAARAARAAR AARTCNAGYAARGARMGNGAYCARTCNAARYTNGAYAGYGGNAARGAYGARAGYAARTCN AARGARAGYGGNAARAGYMGN--------------------------------------- ---------------MGNTCNAARGARMGNGAYAARTCNGGNGAYATHGARMGNGAYAAR AAR------GARGARGTNGAYGCNGGNAGYGCNAARGARGGNGARGCNGTNGGNAARGAR AGYYTNGAYAARGARAARACNAARAARAARGAR------------AARGARTCNGARAGY GTNGAYAARGARGAYAARGARAARAARAARGAYAARAARAARMGNAARMGNGAYAARTCN MGNTCNMGNACNCCNAARMGNTCNAARMGNTCNMGNTCNMGNTCNMGNTCN--------- CCNAARAARTCNAAYCAYAGYCAYMGNAGYMGNCARAGYGARTGGGAYGCNMGNAGYTAY AGYAARGAYTCNAAR---------------------YTNGCNTCNAARGAYMGNTCNMGN TCNMGNTCNMGNGTNGAYAARGAYYTNMGNYTNCARATHGAYAARGCNAARYTNMGNAAR ATHGCNATHGCNAAYACNYTNAGYAGYATGAARTCNGGNCARCCNATGCCNGTNCARGTN GAYGTNGCNGCNGTNAARTCNGGNGGNAARTCNGTNGARGARYTNACNAAYTTYTGYAAR MGNATHTCNGARAARGARCARGARAARYTNGAYAGYGAYAGYAGYGAYGAYGAYGTNGCN AAR---CCNGCNAGYGAYGARGAYGARCCNYTNATHCAYCAYCCNTTYAARGTNAARGAR GCNACNTCNAAYATHGTNATGAAYATHMGNAAYGCNAARCARYTNCCNGTNYTNACNCCN TCNGARAARCARGCNCARCARGCNTCNYTNMGNYTNGCNTTYCCNGTNTCNAGYGGNTCN CAYCAYMGNGCNAAYGARTCNGARTGGGTNCCNGTNGARMGNACNACNGCNCCNCCNGCN CCNACNACNTCNTCNAARCCNGTNGTNGCNTCNCARACNTCNTCNGCNCCNACNCCNCAR ACNACNCARTCN---GCNAGYATHTTYCCNGARGCN---CCNAARGTNGAYATHGGNGCN ATHATHTCNGARMGNYTNCARGCNGTNMGNAARYTNCARGCNAAYCCNTAYGAYGTNCAR GCNYTNAGYTCNATGCAYAARGCNCARCARAARGCNAGYCARTGGGCNCARTCNAARCAY YTNCCNGGNCARTTYACNGGNTCNACNGGNGCNCARGTNYTNTCNCARCARCARATHATG GGNGAYAARMGNCAYCARGCNTGGGCNAARAARTCNCARTTY---------------GTN TCN------------------------------GCNCCNTGGAARCAR------------ ------------------------------------------------------------ ---------------------GGNMGNAARGGNYTNTCNTCNGCNGCNGAYAAYCCNMGN GCNCCNMGNGTNACNAAYGCNAARGAYYTNTCNCAYAARCAYCCN--------------- ---------------------------GTNTCN---------GCNYTNATGGARYTNTGY AAYMGNMGNAAR---------------------------GTNAAYGCNACNGARTCNAGY AARGCNATHYTNCCNTGYTCNGTNAAYAAYYTNGGNACNTTYCARGTNATHTGGACNGAY CARCARGCNACNGTNYTNACNCAYCAYYTNMGNMGNATHATHAAYGAYGARMGNYTNAGY ATHGARCAYAARTTYAARGARGAYTGGAAYYTNCAYATHMGNMGNGTNMGNTAYGGNGAY MGNGGNYTNTAYCAYTGYCARATH------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GTNCARGCNGARGARYTNGGNTGY GARGGNAARGTNGARGARGCNCARGGNGTNATGMGNYTNGTNGAYCARYTNAARGARGAR MGNCARGARYTNGAR------AAYMGNYTNGCNTTYGAYGAR---GGNCCNATGATGAAR CARATGGARGTNTGYGARGTNTGYGGNGCNTTYYTNATHGTNGGNGAYGCNCCNCARMGN CARGAYGARCAYYTNATGGGNAARCARCAYGCNGGNTAYGCNCARGTNMGNGCNGARATH GARMGNMGNAARAARAARGTNMGNGAYGCNATHGAYGCNAARGARGCNTCNGTNGTNAAR YTNMGNGARGARMGNGARGARMGNGARAARGARMGNCARMGNGARMGNGARGARMGNMGN CARMGNGARMGNGAYGTNGARMGNAARMGNGARMGNGAYMGNGAY---------MGNGAR MGNGARMGNGAYMGN------------GARMGNGAYMGNGAYMGNGARMGNGAYMGNMGN MGNMGNMGNTCNMGNAGYMGNGAYMGNGGNGAYMGNMGN---MGNGGNAGYAGYMGNGAR MGN---MGNMGNCARMGNAGYTCNAGYMGNGAYMGNMGNAAYMGNMGNAGYAGYAGYAAR AAYGARGARAGYTCNAGYMGNGGNAARMGNTCNMGNMGNTCNACNAGYMGNGAYMGNAAR CARAGYMGNTCNAARGARTCNGGNTCNMGNAGYCAYGGNGGNTCNMGNAGYMGNGGNGGN TCNMGNGAYMGNGGNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGAYTTYGAY TCNTCNTCNAARTTYATHGCNTCNYTNGCNMGNTTYYTNCARTCNYTNTGYAAYGGNTAY GTNGARTTYGAYAARGGNGTNGARGTNATHGGNCAYATHTAYYTNAGYGTNGAYAGYGAY ACNGGNMGNAARATHGAYTAYGTNYTNAAYGARAARGTNTGYAARAAYGAYAAYTCNGTN ACNTTYATHAGYAAYAGYTTYCAYGCNCARCCNGCNGARAARCCNAARCCNACNCCNAAR GAYTCNGARAAYAARAAYGGNGAYTCNTCNCCNACN------GARGARTCNGARCARYTN CARCCNCAYAGYACNAAYGTNGGNACNACNGGN------------------------YTN TCNCAYGAYAGYTCNTCNAAYAARMGNCCNMGNTCNCCNGCNCARMGNMGNCAYGCNATG GGNCARGGNTCNGGNGGNCCNGCNGCNAARTCNCCNMGNTAYCAY---------GCNGCN TCNMGNTCNTCNAAYTCNGAYATH---CCNTCNATGAAYAAY---TCNATHAGYAAYGAR TAYGAYGAYGGNTCNTAYCARGGNGAYGARGAYAGYAGYCARAAYTAYCCNTCNAAYTTY YTNAAYCARGAY---TAYTCNGGNGCNGAYGTNGAYCARAARCCNGTNATHGAYCCNGAY ATHAGYATHGTNAARGARGARTAYYTNGCNAGYCARCARGCNAGYACNCCNTAYTCNAAY ACNAGYCARACNTCNGGNCCNGGNMGNGGNMGNAGYTCNAGYTCNTCNCARCCNTCNCCN ---------------------------TAYTCNAAYGTNCCNCARAGYTCNAAYTAYTCN TCNGCNGGNGAYTAYTCNAGYTCNATHGARCCNGAYCCNTCNGARYTNACNCCNGCNCAR MGNGARGARYTNGARATGTAYTAYMGNAARGGNACNGAYCARCAYYTNACNTTYYTNMGN AAYATGMGNGARGCNCAYGCNATGTAYCCNTTYACNGGNAARMGNGAYAARGARYTNTTY GAYAARGCNYTNGCNGARNNNNNNNNNNNNNNNCCNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNTTYNNNNNNNNNNNNNNNNNNNNNGGNCARTTYAARTCNCCNGGNATG ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNACNCCNCAYTCNACNGTNAAYATGYTNTCNYTNGCNAARAGYYTNGAY ATHYTNYTNGCNTAYAAYACNTCNAAYATHAAYATGTAYATGTTYGTNGGNGGNACNAAY TTYGGNTTYTTYAAYGGNGCNAAYGARCCNCCNTAYCARCCNGTNCCNACNTCNTAYGAY TAYGAYTCNCCNATHACNGARGCNGGNGAYATHACNYTNAARTAYTAYGCNYTNMGNGAY ATHGTNTCNAARTAYYTNCCNYTNCCNCCNGGNCCNGTNCCNGCNAAYACNACNAARATG AAYTTYGGNTCNGTNCCNGTNACNTTYGTNTCNACNGTNCARGAYGCNYTNCCNTAYYTN TCNCCN---ACNCCNGTNCCNTCNATGTAYCCNGTNTGGATGGARAARATHTCNTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR CCNTCNGTNATGAARAAYGTNGAYTTYYTNTAYYTNGARCAYACNACNGAYATHATHTCN TAYTTYGCNGGNATHCAYGTNAARAARAARYTNCCNAGYTAYATHATHGTNGARGAYATH YTNTCNTAYGCNTCNCARTAYGARGAYMGNCCNYTNGARCARACNYTNGCNMGNYTNYTN GCNYTNATHTCNGAYGCNGCNAAYTGGATHGCNAGYCAYAAYGARGCNCARCARTGYAGY GTNYTNYTNACNGCNCCNTCNMGNATHTCNGCNYTNCAYAAYGTNYTNMGNCARTTYGAY TAYMGNYTNGCNYTNTAYGARGGNCCNAGYAARGARGAYAARTTYTCNAARYTNTCNTTY CARTGYAAYGARACNCAYGTNTCNGTNTCNTTYCARGCNAGYAARGAYAAYATHGTNYTN AAYCARGTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CARACNAGYGGNGARATHTCNGGNCAYTCNACNGAYATHATHGTNAAY AARTTYGARGAYCAYYTNTTYATHATHGCNACNCARTAYMGNAARYTNGGNACNYTNATH GARGTNTCNMGNGAYGTNATHAGYGAYGARGTNCARGGNCARATHCCNATGTTYTCNACN AARGTNYTNYTNGGNAARGAYGARCCNYTNACNCAYGTNATGGCNAARACNATHGTNAAY GCNYTNAAYCCNCCNGTNCCNGTNATHYTNTCNYTNGCNYTNAARGTNACNACNCCNGAR GCNGTNCARCAYGTNATHCARCARATHAARTCNTGYYTNATGGCNAAYAAYATHCAYTTY GARGCNMGNMGNMGNCARATGGTNYTNGAYMGNGCNTGYCARGCNAARAARMGNGCNYTN ATGGARTCNGGNACNGCNCCNGARCCNTCNTCNGARTGYAGYACNAAR------CCNGAR AARATHATGTGYACNGAYCARGGNCARTTYTAYCARACNMGNCCNAGYGTNCAYGTNTGG ACNGGNCCNGARMGNAAYMGNMGNTCNTAYGAYMGNAGYMGNGARGGNCCNGTNYTNCCN AGYTCNTGGMGNCARYTNGGNMGNGARATGAAYTTYMGNGGNAAYTCNYTNAGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGCCNAAR TAYTAYGARGAYATHGARGARAARAGYGAYAARCCNAARGTNGCNTGYTCNGGNATHMGN GAYGAYYTNYTNGARTGYYTNYTNAARAGYGAYTGYTGYAARMGNGAYAARAAYACNCCN MGNGARTGYATG---------AGYAARGTNGGNGAYCCNTCNGTNCCNGAYGARTGYCAY AARYTNMGNATHGCNTTYYTNGARTGYMGNMGNTCNYTNYTNGAYATGMGNACNMGNTTY MGNGGNMGNAARGAR--------------------------------------------- ---MGNAGYACNTAYGTNTTYYTNTTYYTNACNAARTCNTTYTGYGARGARCARTTYAGY GTNYTNATHTCNCAYGCNTGYYTNTAYCARACNYTNTGYGAYCCNGARAGYGTNATHCCN GTNCAYACNGARMGNGARCAYGAYMGNTCNTAYTCNACNCCNYTNTTYYTNACNGCNATH AARCCNATHCARTTYTTYMGNGAYGGNCARTAYCAYATHCARAAYGTNGTNAARYTNTTY CARAGYAARGCNGCNGARMGNYTNMGNMGNGARGTNGCNYTNAAYAARAARMGNYTNGAR TAYTTYAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNTTYGTNGTNGTNCAYTCNGGNGCNGGNATGTAYTCN GCNTCNAAYCARGCNCAYAGYAARGAYYTNTGYAARAARGCNTGYMGNCARGCNATGGAY YTNYTNAARGCNAAYAARTCNGCNGTNGAYGCNGTNACNGCNGCNGTNGTNYTNYTNGAR GARGAYGARTCNACNAAYGCNGGNTAYGGNTCNAAYYTNACNYTNCARGGNAAYGTNGAR TGYGARGCNTGYGTNATGGAYGGNCARTCNCAYTAYTTYGGNGCNGTNGGNGCNATGACN GGNGTNMGNAAYCCNATHAARGTNGCNMGNYTNYTNGTNAARGARCARGARGGNCCNCCN YTNTCNTGGGGNMGNATHAARCCNAGYGTNYTNGTNGGNAARGGNACNMGNTCNTTYTGY GARCARCAYGGNATHGARACNAAYTAYAAYATGATHTCNAARCCNTCNTTYAARACNTAY AAYMGNTAYAARMGNAARTGYGGNYTNATGGARAGYYTNYTN------------------ ---------------------GGNAARGARMGNAARATHCCNAARYTNAARTCNGAYATH CCNAARAGYYTNACNGCNGTNGCNGAR--------------------------------- CCNGCNCARGAYACNGTNGGNGCNATHTGYGTNGAYMGNAAYGGNAAYATHGCNGTNGGN TCNTCNAGYGGNGGNATHTGGYTNAARCAYCCNGGNMGNYTNGGNCCNGTNGCNATGTAY GGNGCNGGNTCNTGGGTNCARAAYCCNCARCCNGCNGGNAARGAYGGNGTNGGNATHGTN GCNTCNGGNTGYGGNGARCAYYTNATGCARACNATHTTYGCNAARACNGTNGCNGAYMGN GTNMGNGARTCNGAYAGYYTNTCNGARTGYYTNCCNAARGTNTTYACNAGYGAYTTYATG GARTCNGARAGYYTNTCNCARCAYAAYGARMGNTAYGCNGGNGCNYTNATHYTNAARYTN MGNGAYTCNGTNATHGCNMGNGARGGNGARYTNGGNTGGATHCAYTCNACNGAYAGYTTY TGYTTYGCNTTYATGGARGARTCNCARACNGCNCCNAARGCNATHATGTCNCAYYTNGCN GAYGARAGYYTNTCNGGNAARTCNTTYGCNATGGGNGGNCAYGTNTTYACNYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYCARTCNATHCAYGTNATH CARCARGARGAYAAYAARGGNAAYACNAAYMGNTAYATHYTNGTNYTNGGNTTYAARAAY ATGGAYGARGARGGNGARGARYTNGARAARCARTCNACNYTNGARGARAAYTAYGGNTTY GTNTAYGAYTTYCAYCCNGTNYTNAARGCNYTNATHAGYTGYYTNACNGGNGTNGTNTTY GGNGTNGCNYTNGARAARGGNMGNGTNTTYGARCCNAGYGTNATHMGNGAYCARATGYTN YTNAARMGNTTYGTNATGYTNAARATGTTYYTNTCNGCNTCNYTNGTNGGNATGYTNTGY ATHTCNYTNATGYTNTCNTAYGARGARACNAARMGNAARATGYTNCARGCNGCNTTYTTY TTYACNAARGGNYTNCARTAYAARACNGCNYTNAGYGCNGTNATHGGNGGNGCNYTNYTN GGNAGYGGNATGGCNATHTCNGGNGCNTGYCCNGGNACNGTNTTYATHCARYTNGGNGCN CARGTNCCNAAYGCNTGGGCNGTNATHGCNGGNGGNYTNYTNGGNACNGCNATHTAYTCN GGNATHGAYTCNAGYYTNCCNGARGCNTTYCAYCARMGNGTNTCNCAYAARTAYTAYTAY YTNAAYMGNTTYTTYAAYGTNTCNTAYTAYGCNTTYGCNATHCCNTTYTCNTTYGCNATG GCNTTYGTNGTNACNGGNATHGARYTNGTNMGNCCNTGGTAYGARGARGTNCCNGARTCN YTNGTNACNGARGGNTTYATGAARGCNGGNGCNTGGCCNCCNTTYATHGCNGGNGCNGTN GTNGGNACNYTNCARATHCCNATHGTNYTNGTNAAYMGNGAYACNYTNGGNTCNGCNACN AGYTAYGTNACNGTNYTNTCNCARGTNTAYCCNYTNTTYAAR---------MGNAAYCCN GCNGARAGYTAYATGAARAARTTYMGNCAYGGNATGYTNAAYTGGTGGCARGTNTTYTAY ATHGGNGGNGCNGTNYTNGGNAGYTAYTGGTCNGCNMGNGCNTCNAAYAGYYTNGGNACN GTNGTNGGNYTNCCNTTYTAYCARGCNTTYGGNGGNGGNGTNYTNYTNYTNTTYGGNTCN MGNYTNGCNGGNGGNTGYACNAGYGGNCAYGGNYTNTCNGGNATGGGNYTNYTNGCNYTN YTNTCNTTYGCNACNGTNCCNGCNATGTTYGCNGGNGGNATGGGNACNGCNTTYTTYATG AARTAYGTNTGGAAYGTNGAYATG------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGTCNGARTAYMGNGGNMGNGGN------AGY AGYMGNGGNMGNGGNGGNGCNCCNMGN------GGNTTYMGN---GGNMGNGGNGGNGGN TTYTTYGAYMGNGAYGGNGAYMGNGGNGGNTTY---MGNGGNMGNGGNGGNTTYTCNMGN GGNMGNGGNGGNCCN------AGYMGNGAYGAYTTYTCNCCNCCNMGN------ATGTCN MGNAAYTAYGAYTCNTCNGAYMGNGGNMGNGGNCCNCCNAGYMGNMGNTTY---GAYMGN TTYGARGAYAGYTTYGAYMGNGGN---TCNTCNTTYMGNTCNAARGAYYTNTAYTCNTCN CCNCCNMGNGAYACNGGNMGNAGYTTYGAYMGNCAYTCNCCNCCN------CCNMGNMGN GAYMGNGARTAYATGCCN---MGNTCNGGNGAYCARTAYAGYTCNTCNMGNGARTAYACN TCNCCNMGNGGNTAYTCNCCNCCNMGNGARTCNGTNTAYGGNTCNTCNTAYAARGAYTCN TTYAGYTCNGGNCCNMGNGARGAR------CCNATGMGNGAYTAYCCNCCNMGN------ TCNAGYGAYTAYAGYGGNAAR------------MGNGAYTTYMGNGAYGGNCCNMGN--- GAYTTY------GCNTCNMGNGAYTAYTCNTCN---------MGNAAYGGNGARTTYMGN GAYTCNTTYAGYAGYMGNGARTTYMGNGARCCNTAYMGNGGNGAYAGYAGYTAYGGNGGN GAYATGMGNGGNGGNMGNGGNGGNMGNGGNMGNTCNMGNTTYGAYGAYMGNGGNCCNCCN MGNGAR---------------------TTYAGYGGNMGNGGNMGNGARGAYMGNGGNMGN GGNTAYMGNGARGAYMGNGGNMGNGGNTTYATGAAYGGNTCNMGNGGNGGNMGN---GGN AGYCCNMGNGGNMGNGGNMGNGAYTTYGCNGGNGGNTTYTCN------GGN---GGNMGN CCN---------GARAARMGNTCNCCNAGYMGNGAYGGN--------------------- ------GCNGGNGGNAARMGNCCNMGNATGGAYACNGGNGAYTAYMGNMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TCNCCNTCNTCNCARGGNACNGAYGARGAR---YTNCARTCN AARATGTCNGCNGAYAAYCCN------ACNTGGCCNYTNACNAGYATHYTNAAYATHGAY GARYTNCCNGARCCNGCNGTNGGNGCNTTYGCNGCN---CAYMGNCCNAGYATHCCNMGN GTNGARGARGCNGAYYTNTTYGARGGNYTNATGMGNMGNAGYATGATGGCNCARYTNGAR CAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNGTNTCNGTNTTYATH GAYYTNTTYATGATGGCNCAYGGNTCNAAR------GARAAYMGNCARYTNTGGTCNAAR AARYTNTAYAGYTGGYTNACNTTYGAYYTNTCNGAYMGNGTNATHMGNGTNGCNYTNYTN GARGTNACNGGNCAYGTNAARGCNGARGCNGAYATHGCNGGNGTNYTNGTNAGYAARATH YTNCARMGNGAYTTYGAYCARACNTCNAARGARGAYTAYYTNYTNCAYATHYTNYTNGTN AARAARTGGMGN---GCNYTNAARGARATGGGNGARGCNGTNAARAARTGYCARTCNYTN AARGCNCCNTCNATGTTYATHCARTGGYTNAAYTCNMGNTGGACNAARGCNTCNGAYTTY ATHCCNAGYGAYTCNMGNYTNCARGGNGCNGCNGTNAGYCARYTNYTNYTNGAYYTNGAY ACNGAYGARGTNYTNGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ACNAAYAARATHATGGTNTCNGCNAARCAYGARGARAARACN GGNGGNTCNTCNGTNACNMGNGARTAYAAYMGNGARGTNAAYGTNCCNGTNGARGTNGAY CCNYTNGCNYTNCARTGYTTYTTYCARCCNGAYGGNTAYYTNGTNTTYAGYGCNCCNATG CCNYTNCCNAARTAYGARGCNGTNAARGAYTCNTCN---CAYCAYTCNCCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARTTYACNGAYGAYGARATH MGNGARGARYTNTCNCAYYTNGGNTAYCAYGAYGTNCCNCARGAYAARYTNGARGAYTTY AARMGNGAYYTNATGAGYYTNATHYTNACNGARMGNAGYAARGCNAGYTCNYTNGAYAGY AGYCARGTNACNGAR---TCNGARGCNAARGARAAYTAYCAYCARGARCCNATHAGYGAY GCNGAYTCNAGYCCNGARGGNAAYTTYAGYAAYCAYTCNAGYCARCAYYTN---GGNAGY AARTTYMGNGARGAYTGGAAYTAYGGNGCNGARTCNMGNCCNCARACN------------ ------------------------------------------GCNCCNGARCARMGNGGN MGNCARGCNMGNGGNMGNMGNACNGARAGYGGNTCNAGYYTNAAYTCNGARCAYYTNGCN CCNTTYAGYYTNGGNMGNAAYCAR------------AGYTGYTGYGAYGAYGTNTCNGAR ACNGAYTCNGARTGYMGNTTYATGAARMGNAARACNTCNMGNAARACNGCNGAYGGNTGY MGNYTNATHGAYGARTCNTTYACNGAYAGYGARTCNGGNGTNTTYGARATHTAYGARAAR ATGAARMGNYTNGCNATGMGNGARTGYGARTGYGGNAARACNMGNCCNAARTCNGGNGAY ATHGTNCCNCCNTAYMGNATGAAR---AARGTNAAYAARTAYCCNTCNGTNATHMGNACN ACNGARCCNCCNCAYACNMGNAAYYTNGTNMGNACNAAYCCNTTYGARMGNCAYAAYCAR TAYAARAARYTNTGGAARGARTGGCCNGTNGTNGGNGARACNGAYMGNATHGCNYTNMGN AARGCNATGCAYGCNAARYTNYTNCAYTCNGARGGNATHAARYTNAARCARAARGTNTAY GTNCCNAAYYTNTAYGTNCCNCCNCAYGARAARGAYMGNCAYGAYATHMGNTGGAARGTN MGNCARGCNATHGARCAYTAYGARATGCCNGARCAYGGNTTYTAYCAYGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ACNAAY CARGTNTAYCARTGYCCNTCNMGNYTNAGYGARMGNTTYTCNGARATGGTNATHATGGAY CARCARATHAARTCNGAYTAYCAYYTNCCNYTNGCNACNGTNATHACNTCNATHATHGAY CCNCARTGYCARAGYCAYAAR------ACNGARATHTCNGAYCCNYTNTCNTCN------ ---GARAARACNTCNCCNAARGARGCNAARGARATHYTNMGNATHMGNCAYAARAARATG AARAARCAYAARYTNMGNAARYTNMGNAARMGNATGTAYTTYYTNTGGMGNAARCARAAR ATGACNMGNAARGCNAARMGNGAYGGNATHTAYTGGAAYGARATHAAYAGYATHAARAAR GARGGNGARGAYTTYGAYGCNGARAGYTTYGTNAARGAYCARYTNCARAARGCNMGNMGN GGNGGNTAYTAYATHAAYGTNYTNGAYTCNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNYTNGTNTCNTCNTTYTCNYTNGCNGGNGTNACN YTNYTNYTNATHGTNACNTTYYTNYTNTTYTAYGCNATHTCNCAYYTNCARATHATHACN GTNGTNAARTCNGTNGCNYTNYTNACNGTNGCNTGYGTNYTNTTYCAYGTNATHGCNATH YTNTTYGGNGCNCCNGTNTTYCARTCNGTNGCNGARACNTTYCAYTTYTCNATHYTNATG ACNGCNYTNGTNGCNTTYCCNTGYTGYGCNGTNGCNGGNCCNAGYYTNGARAARTGGATH GAYATHTTYACNCCNGAR---MGNAARCCNGGNYTNGARACNGTNGTNTGYYTNACNAGY TCNGCNGCNGTNYTNGGNGCNTGGYTNGGNGCNATHCCNATHCCNYTNGAYTGGGAYMGN CCNTGGCARAAYTGGCCNGTNACNTGYTCNGTNGGNTGYGTNYTNGGNTAYTCNGCNGGN YTNTTYYTNGCNTCNYTNTAYYTNCCNCAYCARTAYAARYTNYTNTCNAARACNAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNACNYTNMGNGAYGTNGTNTCNGCNGAYGARAARACNTTY GGNYTNCARGCNCARATHGAYCAYAARGTNACNTTYATHCARGARCARGTNCCNCCNGAY GTNAARYTNATHYTNGTNGGNCAYTCNATHGGNTGYTAYATGATHYTNAAYYTNYTNGAR AARATHGAYTCNAGYTCNGTNYTNMGNTGYTTYTTYYTNTTYCCNACNATHGARMGNATG GCNGTNTCNCCNAAYGGNGCNACNCAYACNCCNGTNTTYMGNTAYTTYMGNTGGATHGTN GTNTTYYTNGCNYTNYTNATHGTNYTNYTNCCNYTNACNATHMGNAARCAYYTNATHMGN YTNGTNTAYMGNAAYGCNGAYTAYCCNGCNTGYATGACNCCNGCNATHYTNACNACNYTN ACNCCNTCNACNGTNAAYTTYTCNACNTTYYTNGCNAARYTNGARATGGGNATHGTNACN AARYTNCARACNGAYYTNGTNMGNAARCAYYTNGAYAARYTNAGYYTNTAYTAYGGNGCN TCNGAYYTNTGGGCNCCNGTNAAYTAYTAYAAYGARYTNAARGAYGARTTYCCNACNATH GAYGCNMGNYTNTGYGARYTNAAYATGAARCAYGCNTTYGTNATGGCNMGNMGNGARGGN CARCARATGGCNGAYATHATGTGGCARTGGYTNTCNACNTGYCAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GTNAARAAYATHYTNAARAARCARGTNYTNGCNACNATHCCNGGNAGYTGG TAYTCNTGYYTNGTNCARYTNAAYACNGARGAYYTNAAYGARGTNCCNTTYYTNGCNGAY AARGTNAARGARAARTAYTCNGARTGGCCNTCNTCNYTNCAYGAYTTYYTNMGNGAYTCN TTYMGNCAYTCNGGNATGMGNGCNGAYMGNCARGARTGYACNACNACNCCNATHAGYCAR AAYATGGCNMGNGGNATGAAYCCNAARAARYTNCAYGARGTNTCNMGNATGGCNTCNYTN ATHGARGAYGTNGTNACNAARACNGARTGYAAYGTNYTNGTNGAYATHGGNTCNGGNYTN GGNTAYYTNGAYCAYGTNYTNCAYCARAARTAYGGNTTYAARATHYTNGGNATGGARATH GARCARGGNCAYTCNTCNGCNGCNGARAARMGNGCNGCNCARCARGGNATHAGYTGYGGN GGNGTNMGNAGYATHCARTGYMGNGTNGARGAYAGYGARTCNATGTAYCCNCARYTNAAR GAYTGYCARTGYGGNCARAGYCARGGNTGYGTNTGYTGYTGYTAYCAYAARATGGCNTAY TCNGAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNGARAARACNTTYACNAARTTYCCNYTN AGYAARGARGGNAARGARYTNTAYGGNAARACNGTNACNAARCAYGGNCARYTNTTYATH ACNCCNTCNACNYTNMGNYTNGGNGCNCARGARACNMGNCAYMGNTGGMGNCARCARTCN CARGCNGAYCAYCARAAYCAYGTNAAYCAYGTNGCNTTYMGNGGNYTNYTNAGYYTNACN GAYGARGARGAYCAYTTYATHMGNCARMGNATHMGNAARTGYAAYTTYGARTCNATHCAR ACNTTYGTNGAYTCNTTYTAYGGNTCNTCNCCNGCNGAYTTYGARAARAARTCNCAYTTY YTNACNYTN------------TGYGARTAYAARAGYCARTTYGAYGCNATHGARGTNTTY ACNYTNYTNCARGTNATHYTNCARCCNGTNATHGARAAYYTNYTNTAYGARGAYMGNGTN CARTGGYTNMGNGARCARGGNTTYYTNAAYGTNGGNATHGTNCCNGTNTTYGAYGARTTY ATHTCNCCNMGNAAYYTNGCNATHGTNGCNYTNAAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYGAYCCNCARACNAAYTTYCCNCCNATGTGYTAYAAYTGGATG GCNACNGCNGGNGTNCAYGARTTYYTNGARMGNATHCAYMGNGCNACNYTNAAYAARCAY TTYAARATGTCN---GAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYCCN TGYCCNYTNGARGARYTNCCNGARGTNGCNAARACNGARGARGCNCARMGNYTNGCNGGN GTNYTNCCNTAYGARGARGCNGARGGNGAYCCNGAYTTYMGNCCNGTNTGGGAYAAYGAR ACNTGGGCNGCNGCNATHGARGARAGYAAR------------------------------ ------------------------GARAAYGARGTNAARGAYGARGAYGAYTTYTTYTCN GAYGCNAARGAYAARACNTCNTCNCCNGAYACNGCNACNCCN---GARTCNACNGTNAAY GGNACNCCNGAYGARGARGAR---GARYTNGARGAYGAYGARGAYGARATGTTYAARGGN GGNAGYTCNGARATHAARYTNGAYTCNGAYGAYGAYGARTCNGCN--------------- ------------------------------------------------------AARATH GAYGCNGCNGTNTCNAARGTNAARGARGCNACNCCNGARATHCCNGTNTCNGARGTNGTN ACNGCNAARACNAARATHGCNGCNCCNTCNYTNAARTCNGAYGARYTNTAYGAYGARCCN GAYGAYAARGARAARAARTAYGAYYTNGARATHAARATHACNGARAAYYTNAARATGGGN GAYGGNATGTCNGCNTAYATGGTNTTYAARATHATHTCNAARACNACNAAYCCNGCNTTY MGNCAYCCNGARAAYACNGTNYTNMGNMGNTTYAGYGAYTTYYTNGGNYTNCAYTCNAAR YTNGCNGARAARCAYGTNCCNYTNGGNGTNATHGTNCCNCCNGCNCCNGARAARAGYGTN ATHGGNATGACNAARGTNAARATGTCNAARGARGAYTCNGGNAAYATHGAYTTYATHGAY MGNMGNAARGCNGCNYTNGARMGNTAYYTNGTNMGNACNGCNGCNCAYCCNGTNYTNGCN GTNGAYCCNGAYTTYATHGARTTYYTNGARAARGAYGGNGAYYTNCCNAARGCNACNAAY ACNTCNGCNYTNAGYGGNGCNGGNYTNATGMGNATGTTYCAYAARGTNGGNGAYACNYTN GARAARATHACNYTNAARGTNGAYGARAGYGAYGARTGGTTYGARGARAARCAYCARCAR ATHGARGCNYTNGAYYTNCARYTNMGNAARYTNCAYACNAGYYTNGARGCNYTNGCNGCN CAYMGNMGNGARYTNTCNAGYAGYACNGCNGTNTTYGCNAARAGYGCNGCNATGYTNGGN AAYGTNGARGARCAYACNGGNYTNTCNMGNGCNYTNTCNCARYTNGCNGARACNGARGAR AARATHGARATHGTNCAYAARGARCARGCNGAYGTNGAYTTYTTYACNATGTCNGARYTN ATGAARGAYTAYGTNATGYTNATHACNGCNGTNAARGARGTNTTYCAYGARMGNATHAAR TGYTAYAARCARTGGAARGAYGCNGARACNACNYTNGGNAARAARMGNGARGTNAARGCN AARATGGARATHCARGGNAARGCNGAYAARATHTCNCARGCNMGNGCNGARATHACNGAR TGGGARCARAARGTNGARAARGGNCARGARGAYTTYGARAARATHTCNAARAAYATHAAR AARGARGTNGCNMGNTTYGARAARYTNMGNGTNAAYGAYTTYAARAAYAAYGTNATHAAR TAYYTNGARGTNYTNATGGAYAAYCARGARAARYTNATHAARCAYTGGGARACNTTYYTN CCNGARGCNAARGCNATHGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNTGYCCNGTNACNGARTGYGGNAARAGYTTYCCNTAYCCNGGNAARYTNMGNMGNCAY ATGAARGTNCAYCARGGNTAYCCNTGYGAYGTNACNGGNTGYGGNCARGTNYTNGCNACN TGYTCNYTNYTNAARAGYCAYAARTCNCAYGCNCAYCCNAARGAYYTNCARTGYCCNGAR TGYAGYGTNGTNYTNTCNTCNCARTCNTGYYTNACNCARCAYMGNAARATHCAYGGNMGN ---AARGARMGNATHGTNTGYACNTGGGARGGNTGYAGYMGNAGYTAYYTNTAYMGNAAR AAYYTNACNCARCAYGTNMGNGCNTTYCAYYTNGGNGARCARGTNTTYATHAARTCNAAR ACNAARAARTCNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CARACNAGYCCNMGNTCNYTNTAYAARGAY AGYTGGCCNAGYYTNTTYATHGCNCCNAARGGNGCNACNACNGARYTNCAYGTNGAYGCN TTYCAYTCNCAYTTYTGGATGGCNYTNTTYGARGGNCARAARMGNTGGATHTTYTTYGAY CAYGARGAYGTNTCNTTYYTNTAYCCNMGNYTNTTYCARTCNATGGAYCCNGTNTTYGAR GTNGAYYTNAGYAARCCNGAYYTNGAYAARTTYCCNYTNYTNTCNYTNACNCARCCNCAR CARTGYGTNYTNCARCCNGGNGARYTNYTNTTYGTNCCNGCNGGNAGYCCNCAYTAYGTN GARAAYYTNACNTCNACNYTNGCNATHTCNTCNAAYTAYGTNGAYCAYACNAAYTAYGAR AARGTNTGYGARGARYTNMGNACNAAYGCNYTNCARGAYGARMGNGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARCCNCARATHAAYCCNGARGTNGTNMGNTCNGGNGTN AAYCARGARGARGCNYTNCCNGARACNGGNTCNGCNAARAARTTYGCNGCNMGNTAYAGY CARYTNGARACNGARMGNAARCARCCNGCNTCNGCNMGNAARAARGARYTNACNCCNGAY MGN---ACNGGNCARGTNGARTAYGTNTCNGARCCNMGNGGNTTYGTNGARCAYTAYGAR GGNAARGCNGARTCNGGNGTNTTYGARAGYGARCCNCARCARTCNGARGAYGTNGTNAAR TCNGGNATHGAYGAY---AAYGARGTNGTNCCNGARMGNGGNACNGCNAARAAYYTNGCN GARMGNTTYMGNCARATHTCNGTNGARAAYGCNGCNCCNGTNTCNAGYMGNAAYMGNMGN GARATHACNCCNGAYAAYTCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CARGGNGTNYTNAGY GGNTCNATHCCNTGGAARGTNYTNCARGARCARTTYTAYAARAAYAAYYTNTAYCARGAY GARATHAGYAARYTNATHGTNTCNCCNGARAARGCNTAYCARATGGGNCARCARTTYGTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARATHATGYTNTGYAARTTYACNYTNMGNCCNTGYYTNCARAAYTGYYTNGAY GGNTAYAAYTTYTGYYTNMGNCAYATHYTNGARGAYAARGCNGCNCCNTTYMGNCARTGY GCNTAYGTNACNAARGTNGGNMGNMGNTGYCCNTCNGCNGCNCCNAARCARGARAARAAR GAYGGNTTYTGYTCNTTYCAYACNAARMGNGCNYTNGTNACNMGNCARMGNYTNGCNMGN AARMGNMGNCCNAARGARACNCCNGAYAGYYTNYTNGARGAYYTNGTNGTNTCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CCN GCNATHGCNCCNGTNCARGARTTYCCNGTNATHACNGARCARGTNGARATHGAYAARCAR GTNYTNATHGAYMGNATHGTNMGNYTNCARAARTCNCAYGCNMGNAARAAYGARAARYTN GARTTYYTNGGNGARCAYATHCARCARYTNYTNGARGARATHAARAARAARACNAARATH ATHCARAGYTAYGTNATGMGNGARGARAGYGGNACNYTNTCNTCNGARGAYATGGAYGCN AAYAARYTNYTNTCNMGNAARGGNGGNATHATGGCNTCNGTNTAYTCNYTNCAYCARCAR GCNATGACNYTNGARYTNTCNYTNCARATHAAYAARAARYTNCARGCNGTNYTNGARGAY ACNYTNYTNAARAAYATHACNYTNAARGARAAYYTNGAYACNYTNGGNGARGARATHGCN MGNYTNTCNCARTTYAAYMGNAARYTNCARYTNCAYYTNCARGARYTNGAR--------- TCNGGNTCNGAYGARACNTAYCARACNTTYATHYTNTAYGAYGARGAYCAYACNYTNGGN AAYGCNYTNAARTAYATHYTNAAYAARAAYCCNGAYGTNTCNTTYGTNGGNTAYAGYATH ACNCAYCCNTCNGARAGYAAYATHAAYYTNMGNATHCARACNACNGGNAARCCNGCNTCN GCNGTNYTNMGNCARGGNYTNGCNGAYYTNAARCARYTNTGYGGNCAYATGYTNACNACN TTYGARTCNTCNACNAARTAYTAYAARGARAAYCAYYTNGAYAGYTCNGCNGAYATGGAY CARTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNYTNGCNATGTGGGAYTTYGARCAYTGYGAYCCNAARAAR TGYACNGGNAARAARYTNAGYTAYAARAAYYTNGTNAARACNYTNCAYYTNAAYCARMGN TTYGGNGGNYTNATHYTNTCNCCNGTNGGNGTNMGNTGYGTNGCNCCNGAYGAYMGNAAR ATHGTNGARGARAAYGGNGTNGCNGTNATHGAYTGYAGYTGGGCNAARYTNCARGAYACN CCNTTYGCNMGNATGAARGGNGAYCARYTNMGNYTNYTNCCNTAYYTNATHGCNGCNAAY CCNATHAAYTAYGGNMGNCCNTGYAARYTNTCNTGYGTNGARGCNTTYGCNGCNACNYTN TAYATHACNGGNTTYATHMGNGARGCNAAYGTNYTNYTNGAYAARTTYMGNTGGGGNTCN TCNTTYTAYACNYTNAAYAARGAYYTNYTNGAYGCNTAYAGYYTNTGYAARACNAGYCAR GARGTNGTNTCNGARCARGAYMGNATHYTNGCNMGNYTNCARGARGAYAARYTNCARGAY AARTCNAARGAYTGGYTNTCNATGGAYCCNGAYGTNGAYGTNTGYAAYCCNAAYMGNCCN YTNTAYCCNCCNTCNGARTCNAGYTCNGAYGARGARACNGARGARGARGARAGYGAY--- GARYTNGAYGARAGYGAYCARGAYTGYGARGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CARACNCCNTCNCCNAGYGAY AGYGGNGTNGGNGARYTNGARGCNATHYTNMGNGARAARGAYGCNGARATHAAYACNYTN MGNGARGTNATGGAYMGNAAYGARMGNGCNATHCCNCARGTNTAYGARGARMGNAARAAY GCNTGGGCNACNGAYACNCARGARYTNMGNGARGARTAYGARMGNAARYTNAARGTNCAR AGYMGNAARTCNTAYAARACNGARCARGTNYTNTCNYTNCARGTNTAYAARYTNCARCAR GAYCARAARTCNYTNTCNGAYGARAARGAYAARGTNGCNGCNGARMGNGAYTCNYTNAAR ACNCARYTNGARAGYGCNAAYTCNAARATHTCNTCNYTNCARGAYCARGTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ACNGCNTGYGTNYTNAAYYTNGGNTGYYTNGTNTTYATGTAYCARTGGCARCCNACNAAR GARTCNYTNGTNCCNTAYTTYGTNGTNATGGGNGTNTGGGGNATHAGYGAYGGNTTYTGG AAYACNCARATHATHAGYYTNATGGGNGTNATHTTYCCNACNAARTTYGARGARGCNTAY TCNGGNYTNMGNATGACNCARGGNYTNAGYGTNGCNATHGCNTTYGGNTAYTCNAAYGCN YTNTGYATGAGYGTNAARATHTAYATHACNATHGCNGTNTGYTGYGTNGGNYTNATHGGN TAYYTNYTNATGGARGTNAARCAYMGNMGNGARGARAARTTYAGYGCNATGAARTTYAAR CARACNACNGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGAGYTCNTCNTGYCARCAY ACNGARTGGATHYTNGARACNATHGAYCAYYTNMGNAARMGNAARGCNMGNCCNGAYYTN AARMGNATHTGYCAYGTNGTNAARMGNMGNTTYGGNYTNTCNAAYGAYGTNACNGARGCN AARYTNGARGGNYTNGTNGAYMGNGARATHGTNATHAARGTNGAYTAYAARGGNAGYACN AGYTAYMGNAAYGCNTCNAARTGG------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARYTNATHCAR MGNTCNAAYAGYYTNGARGTNAGYGAYYTNCAYGCN------------GARGTN------ ------------------GARAARTAYMGNMGNYTNGARGARGAYTTYAARTCNATGGTN GGNGARMGNGAYGARCARATHCAYGCNYTNGCNCARAARACNGCNTCNYTNCARGARGTN GTNTCNGCNMGNGARGCNGARTGYGGNCARATHMGNAARCARYTNGAYAAYGCNAARTTY CARGTNACNGGNYTNATGGCNGARYTNTCNGARGTNAARGTNGARMGNGARTCNATGCAR CARMGNAGYGARTCNCARGGNGARGARTCNAGYAGYYTNMGNACNAGYYTNAAYCARATG ACNYTNGCNGTNMGNAAYAARGAYTCNGARATHAGYTCNYTNMGNGAYCARYTNGCNACN YTNAAYGCNGCNATGGARGGNAARGARGGNGARCARCAYMGNGTNGCNYTNATGGTNAAR GARMGNGARGCNATHGARGCNGCNAGYMGNCAYYTNCARCARGARMGNGAYACNCARGCN AAYYTNGCNGAYCARMGNYTNCARGARATGGARTCNGTNAARGTNGARYTNTCNGCNCAR AARGAYAARGTNTTYAARYTNGGNMGNGARYTNGAYMGNYTNMGNAGYCAYYTNATHGAR ATHGARGAYGGNTAYACNAARGARGCNYTNGARGCNGARGARMGNGARAARGARYTNMGN ACNAARYTNGCNACNGCNGARGARCAYYTNATGAGYTCNTCNTCNCARGTNCARYTNGCN AGYCARGARTCNMGNMGNCAYATHGARAGYYTNGARCARCARYTNCARCAYATHGCNGGN CARMGNGAYAAYGCNTTYATGCARGTNGCNGCNACNCARGAYCARTGYGARCARTAYGCN GCNTCNYTNAARAAYYTNCARYTNGTNYTNGARCAYTTYCARAARGARAARGAYTCNGCN GTNGCNYTNGARACNGARAARTAYCARGARGARGCNCARTCNYTNAARAAYAARGTNAAR GAYATGGARCARGARYTNGTNTCNACNMGNGGNGAYYTNACNGARGCNYTNGAYGGNYTN GARGCNGCNTCNMGNYTNAGYGARCARYTNGAYMGNAARCARGARGCNYTNYTNGCNYTN AARGARGARGTNCARYTNMGNGARGAYGCNYTNAARGCNGCNGARGARGARATHTCNAAR YTNAAYTCNAGYACNGARGCNAARGTNGAYAARATGYTNATGCAYAAYATGGTNYTNACN TGGYTNACNTCNCCNGARAARAARMGNAAYGARATHGTNCARYTNATHGGNCAYGTNYTN GAYTTYAGYCCNGAYGAYTTYTCNAARATHGARTCNGCNCAYAGYCARGAYAGYYTNTGG ATHGGNTTYTTYMGNMGNCCNAARGCNGARTCNCCNACNCCNAGYAARACN------GAY ACNTCNTTYTCNCARYTNTTYGTNAARTTYYTNGARMGNGARTCNTCNCCNCCNCCNACN CCNTTYAARYTNCCNGCNGARACNATGGCNGCNGARACNCARGCNMGNCAYAARACNACN TTYAAYCCNTTYACNGCNCCNMGNCAYGTNACNCAY---GGNACNGARGCNACNGGNGCN TCNGGNAGYTCNTCNCAYYTNYTNATGCCNCARGAYTCNYTNCAYCCNTCNCCNYTNTTY GCNCCNGTNACNAGY---TCNAGYGCNGCNGARAGYGCNATHYTNAARGAYGTNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GGNATGYTNAGYCAYGARAAYATHYTNGTNTTYCAYGCNTCNGAYACNATHGGN MGNTTYTCNTGYACNCARAAYYTNYTNATHGTNCARTAYCAYCCNTAYGGNTCNYTNTAY GAYTAYYTNCARMGNAGYGAYATHGAYATGGARGARATGYTNATHYTNGCNCAYTCNGCN GCNGCNGGNATHAGYCAYYTNCAYTAYGARATHAARCARGGNACNGGNACNCAYGARAAR CCNTCNATHGCNCAYMGNGAYATHAARTCNAARAAYATHYTNGTNAARYTNAGYGGNGAR TGYTGYATHGGNGAYYTNGGNCAYGCNATHAARAAYACNAARCARTGGGAYMGNGGNMGN GARMGNYTNTGGGTNGGNACNAARMGNTAYATGGCNCCNGARYTNYTNGCNAARACNYTN AAYCCNGCNCAYTTYGARTCNTTYMGNTGYGCNGAYGTNTAYGCNTTY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGYTNGTNGAYGTNGGNGCNTGGACNCARGGNATGGCNYTNYTNTGYGAYGAYYTNCAY MGNAARYTNGTNTTYAGYAGYCAYTTYGAYTGYATGTCNAARTTYGCNCCNMGNATHTCN AGYTGYATHYTNATHMGNACNCARATGTTYMGNCARGCNGTNYTNGAYGCNGGNYTNGCN TCNCAYMGNACNYTNCAYGGNATHACNTGYAAYTTYGCNGARAAYATHGTNAAYTGYYTN GARMGNCCNYTNTCNMGNAGYTGYCCNMGNYTNGTNGTNGAYACNYTNGTNACNGCNYTN CAYMGNTTYYTNCCNCCNGCNTGYGCNCCNGTNCCNGCN------------------AGY AAYGARGAYGCNGGNGAYTCNAAYTCNGCNACNGTNYTNGARGCNGTNATHGTNGARGGN GGNGARGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CARCARTCNTAYYTNCAY CARGTNTCNAGYAGYGCNCCNGARGTNGAYATGTCNAGYCCNYTNGTNTCN--------- ATHGGNGGNGAYTTYATHCCNTCNACNTAYGAYYTNYTNGGNGAYTTYACNACNGTN--- ------GARYTNGGNAAYATHYTNAAYGAYAGYGAYYTNATHGARATHCARCCNTCNYTN GCNTCNGAYGGNYTNAAYCARGCNACNATGGTNACNGGNYTNGAYAGYYTNGAYTCNGAR TCNGCNAAYCARACNTCNAAY---------TCNTGYCCNACNCAYCARTAYCAYAGYTCN TCNGAYATHCAYACNGGNATHATGTCNGTNCARGAYGARYTNTGGMGNAARGARMGNATH AARAARGAYAAYCAYAAYATGATHGARMGNMGNMGNMGNTTYAAYATHAAYGAYMGNATH AARGARYTNGGNGGNYTNYTNCCNAARTCNATHGAYCCNGAYTCNMGNCARAAYAARGGN AGYATHYTNAARGCNTCNGTNGAYTAYATHAARATHYTNCARGAYGAYCARAARAARTTY MGNAAYATGATHGAYGARAARAARAARGCNGARYTNGAYYTNMGNAARGTNYTNATHMGN YTNAAYCARATGAAYYTNGTNYTNCARTCNCAYGGNATHGAYACNACNAAYTTYGGNGAY YTNGAYYTN---ACNTCNGCNATHGCNGGNAGYTCNTCNGGNYTNCCNACNTCNYTNCCN TCNATHGARGTNACNCARAGYAAYGGNAAYATGACNACNCARAGYYTNYTNACNAGYGCN ATGTCNCCNATGGAYGARYTN---ATGGAYGARACNTCNCCNGTNAGYGGNGAYCCNATG YTNYTNTCNACNCCNGTNAGYCCNGARCCNGARGAYAGYACNTTYCAYTTY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AAYTCNCARCAYTTYYTNAARGAYTCNGTNTCNAGYCCNTGGGARMGNGCN GTNGCNTCNAAYAARGTNCCNTAYTTYATHAAYCAYGAYACNGARACNACNCARTGGGAY CAYCCNCARYTNACNGCNYTNATGGAYGCNYTNATHGAYYTNAAYAARATHMGNTTYGCN GCNTAYMGNACNGGNATGAARYTNMGNGCNYTNCARAARAARYTNTGYYTNGAYACNGTN GCNYTNCARATGGCNATHGARGCNTTYGAYACNCAYGGNYTNMGNGGNMGNAAYGAYAAR YTNATGGAYGTNGGNGARATGATHGARTGYYTNACNACNATHYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARAARACNMGNATHAAYAAR GCNGTNGARTAYYTNMGNYTNTGGCARAAYGAYMGNAARTCNTGGAARTTYAAYAARGGN TTYCARTCNYTNYTNYTNAARGCNATGTAYAAYCCNGTNATHYTNCCNGARGAYGAYTTY GCNATHGCNYTNYTNTAYTTYGARAARAGYGCNGGNTCNGCNMGNGARAARYTNAARACN GAYGCNATGGCNYTNATHACNGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGGCNGCN CCN---GTNGARAAYAAYTGYYTNCCNTGYGAYGAYTTYATGAARTTYCARGAYGCNYTN AARAARYTNMGNATHATGGAYGAYMGNATHATHCAYGCNYTNAAYAARAAYATHCCNACN YTNTCNTTYCARGARAARGTNGAYACNTCNTCNAAYTGYAARCAYATHTAYGAYGAYATH CARACNTCNTAYAGYCARMGNGARAARTCNATHCARCAYTGYATHMGNYTNGTNGGNGAR GAYGTNAARAARYTNAAYGAYGARMGNCARAARGAYCCNGAYAAYATHGAYGTNYTNAAR TCNYTNMGNMGNGARCARACNAARYTNMGNYTNATGCARCARGARATGAGYGTNGARGAR GTNGTNMGNGAYMGNACNYTNAARGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY TTYMGNYTNCARATHGTNTAYATGGAYTTYGGNATGAARTAYMGNGAYCCNYTNYTNGAR ATGTGGTAYTAYGCNAARGCNCARCCNGAYACNCCNATHAARGGNTCNACNGCNGGNYTN YTN---CCNCCNMGNTTYGTNGAYAAYYTNATHMGNGTNTAYAGYMGNGAYAGYGAYCCN ATHGTNTGYMGNMGNATHCARGAYAGYTTYAAYAAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CCNYTNCAYYTNGAYACNAARAAY GARCAYACNTTYGARATHAARGAYYTNGARATGYTNATHAARCARACNACNAARGAYYTN GARGARYTNGAYAARCARMGNAARGAYGARTTYAARGARTAYGARATGGARAARAARTTY ACNGARGARGARGCNYTNAARCAYATGAGYCCNGARGAYGCNGARAARGARAARCAYMGN YTNGARGCNYTNAARAARAARCAYAAYGARCAYCCNAARGTNCAYCAYCCNGGNAGYAAR GCNCARYTNGARGARGTNTGGGAYGARGARGAYCAYYTNCARGAYCARGAYTTYGAYCCN YTNACNTTYTTYCAYAARCAYGAYGTNAAYCARGAYGGNGTNTGGAGYATHGAYGARGTN GARGCNATHTTYCARCAYGARYTNGAYAARYTNTAYGAYCCNAAYAAYCCNCARGAYGAR GAYGAYCCNGTNGARMGNTAYGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNAARAAYCARAARTGYGARTTYTCNATH AGYGTNGGNAARCAYTCNGCNACNGTNACNGCNAARAAYAARAARGARGGNAARCARYTN GCNTCNCARGCNATHYTNGGNAARYTNCAYCCNCAYATHCCNAGYTGGGGNTCNYTNYTN MGNYTNTAYGGNACNAAYGTNGARAARCCNGTNGAYAARGTNGARGARYTNAAYGARATH AARACNCAYGTNCCNAAYAARGCNGTNYTNGARAGYYTNMGNGARGARATGMGNAARYTN CAYTCNCARAARGCNGCNATHCCNTCNATGGGNAARATGGTNGTNGCNGTNAGYGAYATG CCNGCNCARATGTCNTGYGTNGAYYTNATGGTNGCNTTYGGNYTNCAYATHGGNGCNACN TCNGCNTGYYTNGCNGTNCAYMGNGAYGGNAARACNGAYGTNATHGCNAAYGAYATHGGN GAYMGNGTNACNCCNGCNGTNGTNGCNTTYACNGAYCAYGARATHGCNGTNGGNGCNAGY GCNAARCARGGNGCNATHMGNAAYGCNAGYAAYACNGTNGCNCAYGTNAARCAYATHATH GGNAGYCARATGGARGARYTNCARGTNAARGARTAYACNGAYMGNCAYCARGTNGAYGTN GGNAGYYTNAAYGGNGARATGGTNTTYAAYGTNGARCAYAARGGNAARAARGTNCARTAY ACNCCNAAYAARATHATGGARYTNATHTAYGGNAARATGTTYGARACNGCNCARAGYAAY GGNGGNGCNGCNTCNAARGAYGCNGTNYTNGCNGTNCCNTCNGAYTTYACNGTNMGNCAR ATGAAYGTNYTNMGNGARTGYGCNACNAARGCNGGNTTYAARGTNYTNMGNGTNGTNAAY GARCCNACNTCNGCNYTNYTNGCNTTYGAYGCNGGNCARCAYGAYGARACNGARCAR--- TTYAARACNYTNGTNTAYMGNYTNGGNGGNACNTCNCAYGAYGCNACNYTNTAYAAYGTN GARCAYGGNATGTAYTGYATGYTNGCNGARGCNACNGAYAAYAAYTTYGGNGGNGAYMGN YTNACNGARGTNYTNCARACNTTYYTNGCNACNGARTGYGGNMGNCARYTNMGNTGYGAY ATHMGNGAYAAYAARMGNTCNATGAGYAARYTNAARYTNGCNGCNGARGGNTGYAARCAY TGGYTNAGYTCNATGCCNAAYGCNCARTGYAGYGTNGAYTCNATHTAYGARGGNATGGAY TTYTCNTAYAAYATGTCNMGNGCNMGNTTYGARAGYYTNTGYTCNCCNYTNATGACNCAR TGYTCNCARYTNGTNCARAAYGTNYTNGAYAARGCNGGNTGYACNAARGAYAAYGTNGCN AARGTNATHGTNTGYGGNGGNGGNGCNAARCCNCCNATGATHAARAARATGATGACNGAY TTYYTNGCNAAYTCNACNYTNYTNAAYTCNATHCCNGARGAYGARATHATHGCNATHGGN GCNGCNAARGARGCNGCNYTNYTNGARGGNAAYGAYGARGARAARTTYGARATGGCNGAR GARAGYGTNTTYGCNTTYAARTCNYTNTCNAARGCNGTNTGYYTNAARGTNAAYTCNCCN GARYTNCARGTNATHYTNCCNCARMGNTGYYTNATHCCNGCNMGNAARCARCAYACNYTN ACNYTNCCNCARTCNCARACNAGYGTNAARYTNGARYTNYTNCARGCNGAYGARCCNATH TCNTCNGAYACNGARGCNCARYTNYTNGCNAARATHATHYTNMGNGAYYTNCCNCCNGGN TCNACNATHAARTCNAGYTTYCAYYTNACNMGNCCNTCNCCNCCNACNTTYCCNGARGCN TTYAGYATHTCNTTYGAYGAR------------------ATHGARACNYTNYTNGGNCAY ACNYTNAGYACNAAYAAYGGNACNTGGTAYTTYGAYTTYGCNAAYGAYMGNGCNMGNTAY GAYCAYAAYMGNGGNCARACNAAYAAYTTYTGYGAYTTYCARAAYYTNAGYCCNAARGAY MGNAAR------------------------------------------------------ ------------------------------------------TGYACNGTNYTNMGNCCN GAYTGGYTN---ACNGGNTCNAARYTNATHTCNACNGARGARATHAAYGGNMGNCARTGY TAYGGNTGGGCNAARCARGGNGCNGTNGCNGCNGCNGAYACNTGGTTYGCNACNGCNGAY GGNGTNCCNTGYMGNTAYCAYGARGTNGTNGCNCARATHAAYCAYAAYYTNACNTTYAAY CCNGARACNTAYAARATHGGNCCNCARGAYCCNTCNYTNTTYCARGTNCCNGAYAARTGY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNCARAAYAARAARGAYYTNAAYGARMGNACNYTNAARGAYATHAARGAYAAYYTNGAR AARAARYTNGCNGGNCARCAYAARYTNAGYAARMGNGARGARCARATHTAYGAYGCNYTN AARGAYGTNAGYYTNCCNGCNYTNTTYATGCCNTAYAARACNGGNAAYATHTTYAAYCCN MGNGCNCAYCAYTAYTTYCAYCCNAGYGGNTCNTCNGAYGTNMGNYTNACNCARCCNCCN TCNATGTTYACNYTNCCNCCNYTNCCNAAYAGYAARYTNCCNGTNGTNAAYYTNTTYGAR YTNAGYAARAAYTTYCAYAAYMGNGGNCCNGCNTGGYTNGTNGARMGNTAYATHCARCAR CARCARCCNTCNCARGARGAYTAYCCNCARACNCCNGCNCCNACNTCNGCNYTNCCNCCN AARACNAAYACNACNGCNCARTCNCCNATHAAYGAYAAYATHGGNTCNGCNACNACNCAR MGNAGYATHCARCCNGARGTNGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GGNGAY ACNGCNACNTTYATGYTNMGNMGNCARAAYCCNGAYAAYCAYCARTTYGAYATHGARATH MGNGTNAARCCNATHMGNGGNGGNATHGAYCCNGAYTAYGAYACNAAYTAY--------- TTYAGYTTYCARAARTTYGAYCARGAYGCNATHGTNGGNATGATHGGNGGNTTYTAYGCN YTNGTNYTNYTNATHTGYATHGGNYTNATHATHTTYTTYTAYACNMGNTTYATGGGNATG AAYAARAARTGGGARACNCAYCARYTNGCNGCNATGAARACNGAYACNACNTTYGAYGCN MGNAGYCARGTNTCNCARCCN------GCNTGGTCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MGN GARAAYMGNTTYAARMGNACNGCNGARGCNYTNCARAARTCNGGNYTNTGGGAYGTNGCN ATGAARACNGGNAAYYTNATHMGNMGNAAYCARGCNYTNCARAARGARYTNGARGARTTY AARATGGAYGCNYTNAAYTTYYTNAARTCNGTNATHAARAAYCCNGARAAYMGNGAYATG ATHAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GTNAAYTTYACNTAYACNGTNCAYGTNTTY GAYGAYYTNMGNTCNGCNAARYTNATHGCNCCNCAYCCNYTNAAYCARACNGTNTAYGTN GGNGAYTCNGTNTCNTTYCARTGYTAYATHGARAGYGTNATHACNCCNGAYGTNAARTGG YTNMGNMGNGCNGAYAAYCCNGARYTNYTNMGNGAYTCNAAY------CCNATHAARTAY AARGAYGAYGTNYTNACNYTNYTNAARGGNGCNGGNATHYTNCARGCNAARMGNGAYGGN TCNTTYYTNAAYAARYTNGTNATHCARGGNGTNCARCCNGARGAYGCNGGNATGTAYGTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYTTYCCNGTNATGGGNTTYGTNATGATHATHGCNTTYGCNCCNGGN GGNGCNTTYATHTTYCCNATHGCNTAYATGTAYCCNMGNTTYYTNYTNTCNTCNCAYTTY TGGTCNAARCARCARGCNGARGAYATHMGNCARYTNGARATGMGNAARAARGTNAAYCAY TTYCCNCAYATHYTNGAYTAYATGTAYTCNGARAARTCNTCNAARGARGAYCAYGTNAAR AARATHATHAAYAARYTNGAYACNACNTGGCAYYTNAGYMGNTCNYTNGGNYTNTCNATG MGNMGNAAYAARYTNGTNAARGAYGCNYTNYTNYTNMGNTTYACNGAYGTNGCNATGYTN MGNGARGGNATHCAYAAYYTNTCNCCNGAYGAYYTNGAYMGNGCNTGYACNTGGMGNGGN YTNAAYCCNGARGGNATGGARMGNGARACNAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CAYYTNGCNAAYYTNCARACN AARTGYYTNCAYYTNACNATHTGYATHAAYGARYTNYTNGCNGGNCARMGNATHTTYTCN GTNYTNAARGGNGAYAAYYTNAGYYTNAGYMGNATHTGYGARYTNATGAAYMGNAGYMGN AAYAGYTCNGARATGYTNTGGGAYGGNAARTGYTCNAAYGARGAYMGNTGGGAYATHAAR GARGAYGTNGARGCNCAYATHMGNGAYAARATGGARAARMGNAGYCAYTGGGARGAYGTN AGYYTNTGYYTNGARAAYAGYTAYGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGYTNGARGARGGNAGYAGYGCNATGGAR AARAARATHTCNGCNMGN------CARACNCARGGNCARTGYAARAAY---GGNGGNAAY GGNGAYMGNAARTCNGAYTCNACNCCNACNAARCAYGGNMGN---------AAYTCNAGY AAYGGNGGNGGNGCNAARGCNCARGAYGTNGGNCARACNTCNMGNCCNGTNCCNATHCAR AARTGGGAYMGNTCNTAYAGYGAYMGNMGNCARMGNCARMGNTTYTAYCARGAYGAYMGN CCNTGYGARACNGTNGTNGAYAARYTNGAYATHYTNGAYGTNGTNAGYACN------MGN AARGTNAAYGCNAAYCAYYTNYTNAAYTTYAARTAYACNCCNTAYAAY---GGNMGNAGY GAYGAYCARMGNTGGTGYGGNMGNAAYGGNTCNCAYGGNCAYAGYAAY------TAYMGN AARGTNACNMGNTAYAARAARGARCARTTYYTNCARGCNAGYTGYCARTTYGTNGTNMGN GAYACNGGNGAYTAYGCNGARCARGCNATHGAYTCNGAYGCNYTNGTNGAYTGGGARATG GTNGARYTNGTNMGNAGYTAYACNACNGARCCNGTNACNTGYCCNATHTGYYTNCARATH CCNGCNGCNGGNAARATHGCNAARTGYGGNCAYACNTTYTGYTGGGCNTGYATHYTNCAY TAYATHAARYTNGGNGARGCNGARATHMGNAARTGYCCNATHTGYTAYTTYTCNGTNGAY ATHAARGARYTNMGNAGYGTNCARTGGATHGAYGTNCCNGAYTAYAARATHGGNGAYGAR ATHGARATGMGNYTNATGMGNMGNTCNMGNGGNAGYACNTAYGCNATHCCNAARGAYCAR TGGGGNAAYATGAARGGNGGNYTNATGAAYATHCARGAYGGNGARAAYTCNAARTTYATG AARYTNYTNGTNTCNTCNTGYGAYCARATHAARAARGAYGTNATHGAYMGNGARMGNGAY GCNYTNACNATHCARATGGTNGAYGCNGARGAYTCNGARYTNCCNTTYATHGARATGGCN YTNGARTAYYTNGAYACNMGNGAR------------------AARTCNYTNAARGAYGTN AARACNTTYGAYAAYMGNGGNAARGTNTAYATHCCNGGNATGGGNTCNAARATGGTNMGN TCNCCNAARATHCCNGTNCCN------------------------------------GAR CAYACNGCNCARGAYAGYTCNAAYYTNGAY------------GCNCAYCCNGARGAYAAY YTNGAYGAYAARTCNGARGCN--------------------------------------- ---------------------------------------------------------AAY GCNGTNGAYGAYGCNGGNGCNGCN---------TGYGCNGGNATHGARGARTGYAAYCAY ATHCARTCNACNACNGCN------------------GAYGCNGCNYTNCCNTTYGGNTCN CCNCCNAGYCCNTAYCCNCCNATGCARGAYGCNGARGTNAAYCCNYTNCCNYTNGGNYTN GARGARACNGCNGARCARYTNGARYTNCCNATGGAYCAYCARTCNGARAARCARMGNCAY MGNAARGCNCARACNYTNAGYGCNAARAAYGAYTAYTTYTTYTTYCARGCNTCNACNGGN CARCARATHTAYYTNAAYTCNYTNAAYTCNAARTGYYTNGCNGARGARTAYGGNTCNYTN GARGARAGYCCNGGNGTNATHAARGGNACNGTNGTNGCNATHGARMGNATHTTYATGACN GARGAYGTNMGNAARMGNYTNMGNTAYYTNGGNCAYATHCCNYTNACNTGYGARTTYCAY GTNGTNGARYTNAARYTNAARCCNCCNYTNATHAGYAARGARACNYTNAARGTNTTYGAR GCNGCNTTYGARAARAARMGNAARATGMGNCARCARAARGCNAARGARGAYAARMGNMGN GCNAARAARTTYGARYTNGARCARMGNAARAGYATHGGNYTNTTYCCNGARATGAARATH CCNYTNGAYAAYYTNAAYCAYTTYCCNTCNCAYYTNCCNTCNAAYATGTCNGTNGAYGAR MGNGTNCARGAYTGGYTNAARACNTCNTAYAAYATHAAYGTNAAYGGNCARTGGYTNGCN GCNTGYATHGARTTYATHCARCARGARACNCARAGYTCNCCNCCNAAYTTYGAYCARYTN ACNCARYTNGTNTTYGARCARTGGYTNACNGCNGAYYTNACNGAYGTNGCNYTNCCNGTN YTNCCNGAYGAYGTNTTYTGYACNGAYAARTGYATHYTNCCNYTNACNTAYCCNYTNCAR ATGACNTCNGTNATHGAYGTNTCNGTNCCNYTNTAYAGYCARATHMGNAARYTNCARGGN GARAARGARGCNAAYGTNAAYYTNATHTTYTCNGAYAAYCCNTTYGARTTYGCNGCNTCN CARTCNTTYGCNAAYAGYAGYAARTCNTCNMGNYTNYTNAARYTNGARYTNACNGAYGGN CAYMGNAGYGTNCARGCNATHGARTAYCARCCNATHCARATGYTNTCNGCNGAYYTNYTN CCNGGNGCNAARYTNYTNATHCARGGNTCNGTNYTNTGYMGNMGNCARGTNYTNYTNYTN CARGARGAYAAYGTNTCNGTNYTNGGNGGNGARGTNGAYGAYYTNGTNYTNACNTCNGAY CCNGTNGCNAGYYTNCARGCNGARYTNGARAARAAYAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATHGAYATHAGY GGNTGYATHTCNYTNTCNGGNTGYGTNYTNTAYGCNATHGGNGTNAAYTGYCCNMGNYTN AARCAYYTNAAYYTNMGNGAYTGYGCNACNTTYACNGAYGAYAAYTTYYTNTCNTTYYTN TGYGCNCARMGNCCNYTNAAYYTNGARTAYYTNGAYYTNTCNGGNTGYTGGAAYYTNGGN GAYGAYYTNYTNGTNAARYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYAAR ATHGTNYTNTAYAGYTAYTTYMGNAGYTCNTGYAGYTGGMGNGTNMGNATHGCNYTNGGN YTNAARGGNYTNAARTAYGAYTAYGARGCNGTNCAYYTNGTNAARGGNGARCARAGYACN GARGARTAYAARAARYTNAAYCCNATGGGNTTYYTNCCNTCNYTNAARATHGAYGGNYTN TGYYTNACNCARTCNYTNCCNATHATHGARTAYYTNGAYGARMGNAAYCCNGARCCNGCN YTNYTNCCNAARGAYATGGTNGGNAARGCNAARGTNMGNGCNYTNGCNGARYTNATHAAY AGYGGNATHCARCCNYTNCARAAYYTNAARGTNYTNAARAARGTNGGNGAYACNAARATG GARTGGGCNAARAGYTTYATHACNGAYGGNTTYGARGCNYTNGARAARATGYTNAARGAR TCNTCNGGNACNTAYTGYTAYGGNAAYCAYGTNACNYTNGCNGAYGTNTGYYTNGCNCCN CARGTNGCNTCNGCNGTN---MGNTTYAAYGTNGAYATGACNCARTTYCCNATHATHTCN MGNATHAAYAARGCNYTNGARGARYTNCCNGCNTTYMGNGAYGCNGAYTCNGGNMGNCAR CCNGAYACNCCNGARGAYYTNAARAARGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGTCNGAYAARYTNACNACNMGNGTNGTNCARGTNTCNAAY ATHGCNCCNACNTGYTCNAARGAYCARYTNMGNACNYTNTTYGGNTAYATHGGNMGNGTN AARGARYTNGARATGTAYCCNCCNGARGGNGCNGAYGGN---------GCNGCNMGNGTN GCNTAYGTNGARTTYGAYGAYACNACNACNACNGGNGTNGCNYTNCAYYTNAGYAGYACN GTNTTYATHGAYMGNGCNATHATGATHGTNCCNGTNATGGAYGGNAARTTYCCNGAYGAR AGYACNGCNYTNACNYTNACNCCNTCNGCNGTNGCNGGNATGYTNCCNGGNCARCCNACN TGGCCNGCNAAYGTNGTNTCNCARGTNACNGGNYTNGGNGCNAAYCARGTNATHATGACN AAYGAYCCNMGNYTNGTNTCNYTNGGNYTNCCNCARTAYCCNCCNYTNCCNGCNACNACN GAYCCNAGYAARATHGARGARATHMGNMGNACNGTNTTYATHTCNGAYYTNGAYCARAAR GTNACNCCNGARATGYTNYTNTCNTTYTTYTCNCARACNGGNGARATHAARTAYATHMGN ATGGCNGGNGAYGARAAYGGNCCNGTNMGNAGYGCNTAYATHGARTTYACNGAYCARMGN TGYATHGCNCARGCNYTNAGYTAYAAYAAYGTNGTNTTYCAYGGNAARACNGTNAGYGTN AARCAYGCNACNACNAGYATHATHAARCCNACNCCNMGNTCNGARGCNTCNCARMGNGAR ATHGAYGAYGCNATGAARAARGTNAARGARGCNTCNAARYTNATHTCNGCNGCNGCNAAY AGYGAYMGNGARAAYTCNMGNTCNCCNTCNMGNAARMGNTCNAARTCNMGNGGNMGNAGY MGNTCNMGNTCNAARTCNAARTCNMGNAARTCNMGNTCNMGNTCNAAR---GGNMGNMGN MGNMGNAGYACNTCNMGNCCNMGNAARMGNTCNMGNTCNMGNMGNMGNTCNCCNMGNMGN TCNMGNTCNCCN---MGNMGNMGNMGNTCNMGNTCNMGNGGNMGNGAYGCNCCNGCNGCN CCNCCNGTN------------TCNMGNGAYMGNMGNMGNTCNMGNACNMGNTCNCCNGTN MGNAARAARMGNTCNMGNACNMGNTCNMGN---------MGNMGNTCNMGNACNCCNCCN AARTCNTAYAGYMGNGGNMGNMGNTCNMGNTCNMGNGGNMGNMGNAGYMGNTCNMGNGAY AARAARGAYAARAARGARMGNAARAARAGYAARTCNATGTCNCCNCCNACNYTNGTNAAR GARGGNTCNGCNCCNCCNGARAARGCNGCNTCNCCNGCNAARGCNAAY------GARMGN ACNCCNAGYCCNCCNAARGCNAARAARMGNAGYCCNACNCCNAARAARMGNAGYMGNTCN MGNTCNCCNAGYMGNMGN---AARMGNMGNMGNCAYTCNMGNTCNACNTCN---MGNAAR MGNTCNMGNTCNMGNAGYGGNTCNMGNCAYMGNTCNMGNAARGAYAARAARMGNAGYMGN AGYMGNGAYMGNAARCAYGAY---AGYAARAARAARAGYAGYMGNGAYMGNGAYGAYAAR AARAARGARAGYAGYAGYTCNTCNCARGTNAARMGNGAYTAYGAYGARGARGARAARGGN TTYGCNAGYGAYMGNGCNAGYGAYMGNGGNAAYAGYGARGARGTNGCNAARTCNGAYGAY TCNCCNAARGAYTCNCARCCNCCNACNYTNGARAARGAYACNGAYCAYCARGCNGTNGAY ATGGAYATGAGYGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GCN CCNYTNACNGAYYTNGARAARGARATHATHGCNTGYYTNMGNTCNGGNGGNGAYAARTAY GGNAARAARATGGARGAYCARYTNGAYGCNATGAARCARGCNGTNGCNGARGAYGCNTAY GAYMGNTTYMGNAGYACNATHAAYAAYTCNATGGGNGCNGARGTNAGYTGGAAYACNATH GCNYTNYTNTTYTAYGCNACNAARGGNGTNGTNTCNGCNGTNGGNAARAGYTCNCARGTN GCNGTNCARGCNAARGARTTYACNYTNAARTAYATHAGYGAYACNTTYGTNGGNTGGATH ATGGARCARGGNGGNTTYGAYAGYATGYTNAGYGARAGYGARAGYGAYCCNAAYYTNGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------YTNATHYTNGTNTCN YTNATHYTNTCNACNATHTTYGCNYTNACNAGYTCNCAYYTNTGYATGGTNAGYCCNCCN CARMGNGGNTCNATGGTNGGNYTNAAYAARCCNGGNGCNGCNGAYTGYATHYTNYTNGAY TCNCCNTGYGGNGGNMGNAGYMGNCARCAYCCNAGYGTNGGNYTNMGNGGNGGNAARAAY TTYACNATHAGYGTNCARAARAAYYTNGAYCAYTTYGTNGCNGCNACNCCNGGNAAYTTY ACNATHTCNATHTCNCAYAAYATGGARACNTTYCAYCARYTNGCNACNTTYCCNGAYACN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ACNGAYCARCARYTN AAYACNATGTCNYTNGCNGAYATGTCNGAYTTYTAYCAYGGNTAYATHGARAGYGTNCAR GCNYTNTGYAGYMGNGTNYTNMGNATGGGNCAYATHGGNGAYGGNGGNTGGAAYATHTGY GAYGAYCCNAARATHMGNCCNGAYACNAARAAYTGYYTNGTNTAYTCNTTYGGNATHTCN AAYGARTGGAGYTAY---GAYGAYGCNATGGARTCNTAYGGNTGYGARGTNCAYTCNTAY GAYCCNATGGCNAAYGTNGCNGAYCAYGTNMGNGGNCARMGNATHCAYTTYCAYCARGTN GGNATHGGNGGNGTNAAYGTNGARAARCARCCNGGNAARGCNYTNTTYACNYTNGGNACN ATHMGNAARCARAAYAAYCAYCAYCARAARMGNGTNGAYATHGTNAARATGGAYGTNGAR GGNGCNGARGTNCCNTCNYTNYTNAARGCNGTNGARGARGGNAGYYTNAARGAYGTNACN CARYTNTCNTAYGARATHCAYATGGAYGCNGAYCCNCARMGNGGNGTNYTNGTNAAYCAY YTNAARATHYTNMGNMGNYTNTGGGAYGTNGGNTTYMGNYTNTAYMGNACNACNYTNAAY CCNGCNAAYGGNTAYAARAGYAARYTNCAYGGNGTNCCNMGNACNATGTGYGCNGARGTN AAYTTYGTNAAYATHAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARATHTCNCAY ATGATHGCNTTYATHGAYCARGARGCNTCNGARAARGTNGARGARATHGAYYTNAARGCN GARGARGARTTYAAYATHGARAARGGNMGNYTNGTNCARCARTCNMGNGCNCARATHATH GAYTTYTTYGAYAARAARGTNAARAAYGTNGARYTNCARAARAARATHCARAGYTCNAAY ATGCARAAYAAYGCNMGNYTNGARATHYTNMGNAARAARGARGARTAYGTNAARGARGTN ATGGARGAYGCNMGNGARAARYTNAARAARGTNATHATGGAYAAYCCNAARGARTAYAAY CARATGYTNYTNAARYTNATHGTNCARGCNYTNGTNGGNYTNATHGARCCNAARGTNACN ATHMGNTGYMGNMGNGAYGAYYTNCARACNATHAARGGNGCNATHCCNGAYYTNGTNAAR GARTAYAARGARYTNGTNAARGGNAARTAYCCNYTNGARYTNGTNATGGAYGARGARMGN TTYYTNTCNCCNGARATHTGYGGNGGNGTNGARYTNCARGCNMGNAGYGGNAARATHGTN GTNGTNAAYACNYTNGAYGARMGNYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGCNGARGGNGAYCCNCARTAYACNYTNTAYGAYGGNGGNAAYCARGCNYTNACNYTN GCNGTNAAYCAR---------GGNTCNGARGAYTCNCARGCNGTNCARAGYATHCARTAY ATHTCNTCNGAYGGNGTNCARGTNGCNCAYYTNGAYTCNAAYGAYGTNATHCARGTNGCN CARGCNGGNGAYGGNAGYTTYCARCCNACNGCNGCNGGNTTYCARAGYYTNCARGCNTCN YTNCARCCNCARATHATHTCNAAYTCNACNACNGTNCCNATGTCNACNGGNACNGCNCAR GTNGGNACNATHYTNCARGGNCARAAYGTNYTNMGNAAYGTNACNCARCARGCNTCNCAR CARGTNTCNCARCAR------------ACNGCNGGNTCNTCNAGYCCNGTNGCNGGNACN GCN---GCNGGNATHCCNCARATGYTNTTYYTNAAYCARGTNACNATHAAYGGNCARACN TCNTTYGTNYTNGTNGAYGCNAAYAAYAARCCNATHCARYTNCCNCARGGNATHCARGTN ATHAAYYTNCCNCAYCARCARYTNTCNGGNCARTCNATHCARATGCCNGGNAGYGAYTCN GGNGAYGARCCNYTNTAYGTNAAYGCNAARCARTAYCAYMGNATHYTNAARMGNMGNCAR GCNMGNGCNAARYTNGARCARGARTGYAARATHCCNAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGGGNAARAARCAYAARCAYGGNAARCAY--- TCNTCNTCNAGYAGYAGYTCNTCNAGYAGYGAYTCNTCNGAYGAYGARTGGAARCAYYTN CCNAARCAYGARAARAARATGMGNAARAARTGGAARAARCARTCNMGNAARGGNATGATH CCNCAYGGNACNYTNCCNCCNTGGCAYGGNGGNCCNATGTGGGCNCCNCCNATGAARGCN ---------GGNAARAARGGNAARCCNGGNAARCAYGGNGCN------------------ ---GTNCCNGGN------GGN---------------------TAYCCNCCNGGNGCNTAY CCNACNGGN------AGYCAYCCNCCNCCNATGGGNTAYCCNGCNCAYCARCCNGGN--- TAYCCN------------CARAAYCCNGCNTAYCCNCCNCCNGCNCARGGNGGNCCNGGN GGNCCNCCNCCNATGGCNTAYCCNACNGGNGCNCCNCCNCCNGGNGGNTAYCCNACNGGN GCNTAYCCNCCNCCNGCNCARTAYGCNCCNCCNGGNGGNGGNGCNTAYGGNGCNCAYGGN GCNCCNTCNGGNCCNTTYCARGCNCCNCCN------GGNAAY------CCN------GGN TAYCCNCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GAYACNAGYTCNMGNMGNTAYGAYACNTCNTTYAGYGGNCAYGAYGGNCCNACNATH CCNYTNYTNCARYTNCARAARAGYACNTGGCAYACNGARATHGARCCNCCNATHTAYGAY TAYGARMGNYTNAARATHACNAAYTTYGAYYTNCCNAARGAYGTNGAYATHAAYCAYYTN GARATHCAYYTNGGNAAYGARGAYTTYGARGARYTNTTYAARATGCCNMGNGARMGNTTY TAYMGNATGGCNGARTGGAARMGNAAYGAYGTNAARMGNAARYTN--------------- ---------------------------------------------------ACNACNGGN TCNGAYACNGARATGGARTTYGAYTGGGAYMGNATHATHAAYCARTCNTCNYTNTTYGAY GCNATHACNTTYAARCCNGCNGCNACNGTNCARTAYAARTCNGCNATGGCNTTYAGYAAR YTNATHGARTAYGAYGAYGTNGGNGAYGAYGCNAAYTTYGARGARGCNAARAARCARAAR GAYCARTCNACNGTNMGNGGNTTYACNAARACNGTNTGGATGACNCARAARATHGAYGAR AARAARAAYACNTTYAGYTTYAAYACNACNGAYGAYGGNTTYGCNCCNATGGARTCNAAY AAYGGNAGYYTNTCNYTNAARTTYCAYGTNCCNTCNGAYAAYGGNMGNGARCCNGARYTN CCNGCNCARAARTTYAAYGCNAAYGARACNYTNTTYACNTTYGTNYTNGAYAAYTTYACN CCNTCNTAYAAYCAYTCNMGNTTYGCNYTNGARGTNATHGCNGTNAGYTCNGTNAARGAY AARAARATGAARATHGAYACNGTNAGYACNATHGAYGAYGARTAYTCNCCNGGNGTNTTY YTNYTNACNAAYYTNYTNACNAAYCCNGAYGAYACNTCNACNGCNGGNTAYATGCARTGG AARCCNGTNAGYTAYYTNGGNAARACNMGNGGNMGNAARACNTCNACNAARGTNGARCAY GGNGAYYTNATHAARGTNGAYGARMGNGARMGNYTNAAYGCNTCNATHYTNGCNGCNYTN TTYGGNGARGAYYTNTTYAAYGAYGTNGCNGAYGTNAARAARYTNAGY---ATHTCNTTY GGNCARCCNAARGAYGGNTTYTAYYTNAARAAYAAYTAYACNGTNTGGACNGGNGGNATH GGNTAYGGNCARCCNCCNAARGAYGARATHTCNYTNACNGTNATHATHATHATHTCNGCN GGNYTNGGNATHCCNGTNYTNYTNATHATHTTYGGNGGNATHTTYACNGTNGTNMGN--- ------------------------------------------------------------ ------------------ATHAARGTNYTNGARTTYGTNYTNTCNATHTTYGCNTTYGCN ACNACNACNGGNCCNGAYYTNTCNACNACNTTYACNGTNAARAAYTGYAGYAARTGGACN AAYAAYACNGTNAARACNGGNGCNTCNYTNACNTAYTCNTAYAGYTAYCCNTAYGAYYTN GARAAYACNTGYTTYTCNGTNCCNGTNTGYACNGGNGCN---ACNACNYTNATHAARAAR TCNGTNTGYYTNYTNGARGGNTCNCARTCNTCNGCNCARTTYTAYGTNTTYGTNGGNGTN ATHGTNTTYYTNTAYTGYYTNGGNGCNYTNGCNYTNTAYATHTTYTTYGAYGARTTYTAY MGNMGNAAYACNMGNGTNGTNGTNGTNGAYTTYGTNGTNTCNATHGTNYTNACNYTNYTN TGGATHATHGCNTCNTCNGCNTGGGCNGCNGGNYTNAAYGAYGTNAARYTNTAYGCNGAY CCNCAYGAYGGNGARATHTTY---GARTCNATGCCNGARTGY---CARACNAARGGNGAY TGYACNACNAAYAGYGGNGGNAAYTAYGCNACNYTNAAYGTNTCNATHATHTTYGGNTTY YTNAAYTTYGGNGTNTGGGTNGGNAAYYTNTGGTTYYTNTAYAARGARACNCCNTGGTTY AARGTNCARGCNAARCCNCCNACNCARCCN------------------------------ ------------------------------------------CARAARYTNAAYGAYAGY ACNAAYYTNAAYGARTTYYTNAARAGYTTYACNGAYATHGCNGARAARTGYYTNGAR--- AAYGGNTAYGCNCCNACNCAYCAYAGYGTNYTNAAYCAYAAYATHYTNCARCARATHCAR GARATHGGNTGGGARAARGTNCAYAGYYTNTCNGAYGAYATHTCNACNGTNGARTTYGGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ACNCARCCNCCNCCNCCNCCNCCNCCNCCN CCNCCNTCNGCNCCNGARGAYCCNGAYAARGCNCARGAYGAYAAYAGYATGGAYATHGCN TCNGAYGGNGARGAYGAYCARCARAAYGCNATGGGNCARCCNCARCARATGGGNATGGGN CCNATGCARCARCCNCARCARCARCARTGGTGGCCNGGNGGNTCNAAYCARATGTGGATG CCNCARCAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTAYAAYGGNATHGGNYTNCARACN CCNMGNGGNAGYGGNACNAAYGGNTAYGTNCARMGNAAYYTNGCNTTYGTNAARTCNCAY AARGAYMGNACNGAYTAYAARAGYGARGARGAYYTNCARAARYTNGARCARTCNATGAAY AARCARCCNAAYCARGARATHYTNGAYCAYGARMGNAARMGNAARGTNGARYTNAARTGY ATGGARATGCARGARYTNATGGARGARCARGGNTAYACNAGYAARGARGTNACNGAYAAR GTNAAYATGTTYMGNAARATGYTNATGGCNAARGARGGNGTNTCNGAY---ACNCCNTAY GARAARGAYGARCAYGGNAARCCNATHGTNAARGARACNCAYCARYTNGCNGARGCNAAY CARATHAARAAYGAYAARYTNAARGARGCNTTYGGNYTNGGNGAYTAYGTNGAYGGNAGY TCNTTYGAYCCNAAYMGNAARGCNAARGARGARCARGCNAARGCNGCNGCNYTNGCNCAR AARAARTAYAGYATHGTNAAYAGYTCNGAY---GAYGARGCNGARAARGARAGYTCNCCN GTNCCNAARAARAARAARAARAARTCNMGNCAYGARGAYGCNTCNTCNCCNGARAARAGY AARGARAARMGNAARAARAGYMGNAARCAYGGNMGNMGNGAYMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARGAYYTN AAYAARGCNMGNGCNAAYTAYGCNGARYTNGARTCNACNATHGGNAARYTNAARGCNAGY YTNCARACNAAYACNTCNAAYCARAAYAARGAYMGNTCNMGNATHCARGARYTNTCNGAR GARATHATGAARYTNGTNAARMGNCAYAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYCCNTTYAARGAYGCNGAYGTNATHCAYGAYTAYCAYGAYTAYTAYAARACN CARGCNATHAAY---CARCAYYTNGARGAYTAYTAYACNGAYGTNTCNTCNGCNGTNMGN CAYGTNACNYTNTCNGARAGYCAYMGNGTNGCNGTNAARATHAARYTNAARTTYAARTTY AARTTYTAYGGNCAYGARATHGAYACNGTNACNGTNGCNACNGGNGGNTTYATHTAYATG AGYCCNTTYYTNCAYTCNTGGYTNACNGCNACNCARTAYGTNGCNCCNYTNATGGCNAAY TTYGAYCCNTCNYTNCAYGCNGGNTCNCAYATHTAYTAYATGAAYGAYGAYGAYAARATG ACNGTNGARTGGAGYCARATHAARYTNCARGAYCARMGNGARGTNGGNAAYTTYACNTTY CARGCNACNYTNTTYAARAAYAGYAGYATHMGNTTYGCNTAYAARCAYATHCCNGTNGGN YTNGAYACNATHTCNGAYAARAAYCAYCCNGTNAARGTNGGNYTNTCNGAYGCNTTYTAY AARGAYMGNTAYYTNTCNCARTTYMGNATHCAYCARMGNMGNATHTAYGARTAYCAYCAR GTNMGNATHACNCARAGYTTYGTNMGNACNGGNGCNGTNATHAAYGTNAAYCCNYTNCCN ACNTGYAAYYTNATGACNGAYTGYCARTCNTGYACNCARCARGTNAAYATHTCNTTYGAY TGYMGNTGGTGYAAYGARATHGGNMGNTGYTCNAAYGGNTTYGAYTGGTAYMGNCARCAY TGGGAYAAYTAYGGNTGYAAYTCNYTNGCNATGAAYAARACNGTNGAYTGYAARAAYGTN AARCCNCCNAARAARCCNATHGTNACNCCNCCNYTNGGNCCNCARAARCARAARGAYAAR TGYGCNGAYGGNAAYTGYGAYAARAGYTCNAAYGCNTCNGTNGCNGTNATHGCNGTN--- GTNGTNATHATHATHGTNGCNGTNGTNGGNGGNYTNGCNGGNTGGACNTAYTAYGCNTAY ACNCAYCCNACNTCNAARTCNGGNATGTGGYTNATGGARCAYMGNCCNAGYCARYTNAAR GCNAARATHAARTTYTGGAARAGYTCNAGYGGNGCNGCNGCNAARTAYMGNGCNGARAGY GARGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARGCNGARGARTAYAAYAAYGAYAGYCARMGNGTNAGYTCNATH YTNAGYAARATGTCNYTNAGYCARAAYAGYTTYTCNCCNCCNGGNYTNTCNTGYYTNCAR ACNYTNGCNCARGTNGGNGCNGCNYTNAAYGTNMGNGAYCCNTCNGAYGCNAGYTTYYTN YTNTCNATGAARGAYYTNCARGCNGCNGTNAGYAARGTNTCNCARGARYTNYTNTCNCAY GCNCARGAYTCNCAYMGNYTNTCNAARAARATGCARGAYGTNYTNAAYAARAAYGAYTCN YTNGARAARACNYTNGAYGCNGTNGARAARAARTCNAARAARACNCARTCNCARAAYGCN GARMGNAARGARGARATHGTNYTNYTNCARGARAARACNGARGCNAAYAAYTCNAARATG TCNAARYTNAARACNGAYYTNTCNAARACNGGNYTNAGYTCNTCNTGYTCNCAYGGNGAY YTNGTNAARAARMGNGARAARYTNGARAARYTNGARAGYGARYTNGGNCCNATGAARGCN GARYTNGARTCNTTYGCNAGYYTNCCNCCNAAYGCNGTNGARGCNAARGTNAARATHGAR CARYTNAARMGNAARYTNCAYCARGTNCARGCNAARATGACNGARTGYATHGARACNACN AAYACN------------------------------------------------------ ---------------------------------------TGYCCNAAYCCNGGNAGYCAR AAYAGYTTYGAYATHAAYCARTAYYTNGGNMGNTGGTAYGARTAYAARMGNTTYAGYGCN TGGTTYGARGCNGGNGTNGTNTGYGGNAGYGCNYTNTAYGGNYTNMGNGAYGAYGGNAAR YTNAGYGTNATHAAYGGNGGNMGNMGNGARATHAARYTNTTYGGNCAYGTNATHAGYACN AGYAAYACNTCNATHACNGGNACNGCNACNATHCCNAAYCCNAAYMGNCCNTCNGARYTN ACNGTNTCNTTYTCNMGNTTYGAY---CCNGGNACNGGNCCNGCNAAYTAYTTYATHGTN GARACNGAYTAYACNGGNTAYACNGTNGTNTTYTCNTGYACNGAYYTNCCNGGNTTYAGY YTNAGYATHCARTAYGCNTGGATHATGACNMGNGARMGNGGNGTNGCNCCNCCNAAYYTN GCNGCNATHAARGCNAAYYTNCARTCNGCNGGNGTNGAYYTNAGYAAYTTYAAYTCNGTN GAYCARTCNAAYTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNGTNMGNMGNGTNGTNGGNGGNMGNCAR ATGGCNATGGGNGCNTGGCCNTGGYTNGTNTCNYTNAAYTTYYTNGARCAYCAYGAYTAY YTNTCNYTNCARGGNYTNGAYCAYYTNTGYGGNGGNACNYTNATHCAYTCNTAYTGGGTN ATHACNGCNGCNCAYTGYGTNCAYMGNGCNACNGGN---GCNGGNYTNGGNGARGCNGAY AAYTGGYTNGCNGTNYTNGGNGARTAYAAYMGNMGNGTNACNGARCARTCNGARCARMGN ATHCARGTNGCNMGNATHTTYGTNTCNTCNAAYTAYTCNTTYTCNCCNAAYYTNACNGGN GAYATHGCNYTNYTNAARYTNGCNMGNCCNGCNATGGTNACNCARTCNGTNATGCCNATH AGYATHGAYGCNTCNMGNGAYATHCCNGCNGGNACNGARTGYAARACNGCNGGNTGGGGN CARCAYGTNGCNGAYYTNCCNGGNGGNCCNCARTAYGGNAAYGGNACNYTNGTNCCNCAY GTNATHGARACNGCNAARGTNGCNACNAAYMGNTGYCARGARGCNTAYMGNTCNTCNTGG CCNYTNATHGAYGAYTCNGTNYTNTGYTTYCARTCNTCNGARMGNAARGAYGCNTGYCAR GGNGAYTCNGGNGGNCCNYTNGTNTGYTCNAAYGARGCNGGNGTNYTNACNYTNACNGGN ATHGTNTCNATHGGNMGNGGNTGYGCNYTNCCNAAYTTYCCNGGNGTNTAYACNMGNGTN TCNGARTAYMGNAAYTGGATHYTNTCNACNATHMGNCARCAYACN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TGYAGYMGNAARAARCCNYTNMGNTTYYTNYTNATGGGNYTNGAY GCNGCNGGNAARACNAGYYTNYTNTAYMGNATGAARATHGGNCARGTNGTNACNACNATH CCNACNATHGGNTTYAAYGTNGARACNYTN---AGYTAYAARGGNATHGARATHACNGGN TGGGAYGTNGGNGGNMGNGAYAARATGMGNCCNYTNYTNMGNCAYTAYTAYGCNAAYACN GAYGCNGTNATHTAYGTNATHGAYAGYAGYGAYMGNGARMGNATHGAYTTYGCNATHGAY GARYTNAARMGNTTYGTNYTNGARAGYGARGARYTNGARGGNGCNGTNGTNATGGTNYTN GCNAAYAARCARGAYYTNAARTCNCCNATGGCNCCNGCNGARATHGARGAYCARYTNMGN AARAARTGYACNYTNGGNTTYAAYATGACNGTNTTYGTNATGCCNTGYAGYGTNATGACN GGNGAY------GGNATGTGGGARGCNTTYGAYMGNTTYGTNAGYYTNACNAARGARAAR CARGAR------------------------------------------------------ ---------ACNGGNAARGTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AGYGGNYTNATH GGNMGNAGYTTYGCNATGATHTTYGCNAGYGCNGGNTAYGAYGTNCARATHTAYGAYYTN GARCCNCARCARACNTCNGCNGCNAARGARGAYATHYTNAARCARYTNACNTCNYTNGAR AARGAYGGNYTNYTNMGNGGNAARYTNACNMGNGAYCARCARTTYGARAARATHTCNACN ACNGARTGYYTNGARGARTGYGTNACNGGNGCNTTYTTYATHCARGARTGYGTNCCNGAR MGNYTNGAYATHAARAARTCNGTNTGGTCNAARATHGAYAARATHGTNGAYTCNAARGCN ATHYTNTCNACNTCNACNAGYGCNYTNYTNCCNTCNAARATHTCNGAYGARYTNAGYCAY AARCAYMGNTTYATHGTNTGYCAYCCNACNAAYCCNCCNTAYTAYGCNCCNGCNACNGAR GTNGTNCCNGCNTCNTGGACNGARCCNGARGTNGTNGARAARACNYTNACNYTNYTNAAR GAYGTNGGNCARGTNCCNATHYTNGTNAARAARGARGTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNAGYACNGCNAARGGNGCNTGYGCNCCNGAR GARGARTTYGCNCARTGYCCNGTNTGYYTNTCNGARTAYGARGAYGGNGARGARAARMGN ATGYTNCCNTGYAARCAYGARYTNCAYAARATHTGYATHGAYACNTGGYTNAARAAYAAY ACNACNTGYCCNGTNTGYMGNAARGAYGTNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ACNTGGAGYMGNCARATHGCNYTNACNMGNAAYYTNMGNCAR GARGAYGARGAYGTN------GAYAGYGARCARGTNGARGARCCNGGNMGNAARATHGTN GAYGTNGARACNAGYATHMGNTAYYTNAAYAGYAARGCNTTYGTNGARGGNTAYGGNGAR AARCCNGTNTGGTTYCAYTAYMGNMGNAAYTTYAARGGNAAYATHATGCCNCCNACNMGN AARAARTGYATHMGNCARGGNMGNGTNCARACNGCNAGYCCNTGYCCNGTNTGYMGNGAY GARTAYYTNGTNYTNGAYGCNACNAAYGTNAARYTNYTNGARCARTTYATHTCNCCNCAY ACNGGNGAYATHYTNGAYTCNATGAARACNGGNYTNTGYCARGAYCARCARMGNMGNYTN ACNGTNGARGTNATGAARGCNTGGGAYCARGGNTAYGTNGARATGAARGTNCCNTTYMGN ACNTAYAAYTAYGARGAYTAYAARAGY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MGNYTNAARGGN YTNMGNAARGTNGARYTNAARTCNCAYCCNACNTGYTTYTGGMGNACNCARGGNGGNYTN CCNCARACNTAYYTNGCNACNATHGARGCNATHTAYTAYTTYTTYMGNGARTTYCAYAAR GTNTTYATHGGNACNGAYTAYGAYCAYCARTAYGAYAAYYTNYTNTTYTTYTTYAAYTTY ATGCAYMGNAARATHAAR------------ATHYTNATHGTNCARMGNMGNCARMGNYTN TTYTAYCARGCNYTNGGNAARCAYMGNGARYTNGCNGARMGNAARGGNYTNCCNCARCAY TTYGGNGGNTAYTAYGCNATGGGNTTYGCNYTNGTNATGGARGGNGTNATGAGYGGNGGN TAYCAYGTNTGYCCNAGYTAYAAYAAYTTYCARTTYGAYACNTCNTTYATGTAYATHATH GCNTGYYTNTGYATGYTNMGNATHTAYCARTCNMGNCAYGCNGAYATHTGYGCNAARGCN CAYACNGCNTAYTTYTCNATGGCNTTYGTNATHYTNATHGCNYTNYTNGGNGTNGTNTAY MGNAGYAAYGTNGTNTGGATHYTNTAYGCNYTNATHCAYATGTTYTTYACNYTNGTNYTN TCNGCNCARGTNTAYTTYYTNGGNMGNTGGMGNGTNGGNTGGACNTTYTTYAARMGNTTY GTNYTNTTYYTNTAYAAYGAYTGYMGNMGNTGYTCNMGNCCNACNAGYCCNCAYMGNTTY ATHATGYTNYTNATHGGNAAYGTNATHAAYTGGTCNTTYGCNYTNTAYGGNGCNATHGGN CARCCNTCNGAYTTYGCNAGYTAYYTNYTNGCNGTNTTYATHGGNAAYYTNYTNYTNTAY TGYYTNTAYTAYYTNYTNATGAARTGYATHAGYAARGARMGNATHGGNATHYTNGTNYTN TTYGTNATGGGNATHGCNYTNGTNTGYTGGGTNGCNGCNYTNTAYTTYTTYTTYCARCAY YTNACNTCNTGGCARYTNACNCCNTCNGGNTCNMGNGARGGNAAYMGNGARTGYATHYTN YTNCAYTTYTAYGAYGCNCAYGAYGTNTGGCAYATHYTNTCNGCNTTYGGNYTNTTYTTY TCNTTYATGATHYTNYTNATHYTNGAYGAYGAYYTNCAYYTNMGNCCNMGNGAYCARATH CCNGTNTTYGAYTCNMGNGCNGAYGCNGCNTCNGTNGTNGCNGTNACNGCNGCNGAYGAR CCN------AARACNGAYGGNMGNAGYAGYGTNGARCCNAARGARGGNGCNGARTTYMGN GGNGARGAYMGNACNGARATGYTNCCNCCNGARGGNACNGARGAYAGYMGNGGNCARGGN CARTGGAARTCNGCNGARCARCARTAYGTNGCNTCNGCNGTNYTNGCNCARAARAGYGAR ------------CARGAYGCNATHMGNGARYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNTTYAARAGYGAYYTNAGY YTNGAYAARYTNTAYCCNAAYTCNAAYTCNGAYTTYCCNMGNCARCAR---AAYCAYAAY AARGCNGGNGARACNACNGARTCNTTYTCNGGNACNATHCCNATHGAYGARYTNGARATH TCNCAYAGYMGNAGYGGNGGNCCNGGNGGNCARAAYGTNAAYAARGTNAAYAGYAARGTN GARATGMGNTTYCAYGTNGARTCNGCNTCNTGGATHCCNGAYTGGATHAARCCNMGNYTN YTNCARCARGARGARAAYMGNATHACNAARGAYGGNTTYYTNGTNGTNMGNTCNGARATG ACNMGNAARCARYTNYTNAAYCARGCNGAYTGYYTNCARAARYTNMGNAGYATGATHTTY AARGCNTCNTTYYTNCCNCCNGARCCNTCNGARGARGAYATHAARAARMGNGARMGNMGN GCNYTNAARGCNAARGARACNGTNYTNMGNGARAARMGNAGYMGNTCNYTNATHAARCAR TCNCARTCNAARCCNGARYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TTYAARGAYATHCCN YTNAAYCCNTAYGARATHGARATHMGNAARYTNCARGAYATGGCNCARCARATGAARATH CARAGYACNATHGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CAYGTNACNACN YTNATGGAYGAYTCNMGNATGTCNGARTGGCARGCNGCNATHGTNGCNYTNAARAAYGCN GTNATHGGNAGYAAYMGNGARAARCAYAARGTNATHMGNCARGGNYTNATHCCNMGNYTN YTNAGYTGGATHGAYGARGARGCNTGYCCNGTNGARYTNAARACNGARGCNGTNATHGTN YTNTGYAGYYTNGCNAARGGNGGNCAYAAYTGYGTNGAYTCNYTNGTNCARGCNAARGCN GTNCCNATHYTNYTNMGNTCNACNAAYGCNCAYTCNACNYTNTAYACNGARGCNGTNYTN MGNTGYYTNMGNTCNATHTTYATGGARAAYACNGARGAYGTNGAYTAYYTNTAYGARGAR AAYAGYTGYCAYYTNTCNTAYATHTCNTCNTTYATHTCNGTNGTNAAYCARTCNAAYGTN TGYAAYGARTGYGTNGCNAAYATHYTNGTNTGYGGNTGYAARACNAARGCNCAYCARATG TGYYTNYTNAAYGCNGAYGTNATHCARATHYTNACNCCNYTNYTN---ACNTCNAAYYTN TAYAARGTNCARYTNCCNACNYTNAARTTYTTYGCNAARTTYTGYTAYAARAAYAARGAR GTNTCNTCNGCNATHGTNAARGAYGGNAARYTNGTNGAYACNTTYGTNGAYYTNATGGCN MGNGAYAARCCNTCNGARATGCARGTNGCNGCNGCNGARGTNYTNACNAAYYTNCAYMGN TGYGGNATGATGGCNGARAAYAGYTTYATHATHAGYMGNAAYACNYTNGGNACNYTNGTN MGNATGTGYCARAAYGAYMGNACNATHCARGARAARGTNMGNGGNGCNGAYATHYTNGCN TAYYTNATHGARATHGAYCCNGARYTNCARGTNATHGCNAGYTAYTCNTTYCAYYTNATH CARGCNYTNTCNTGGTGYYTNMGNTAYAARAAYTTYTCNTCNYTNTCNACNGAYCARAAR GARAARATHGAYTGGGCNAGYGARATGMGNMGNGCNGCNTTYAARGCNTTYGCNTCNATH AGYGCNAAYGAYGARGARATHMGNGARAARGTNATHAARCARGARGGNYTNGTNGARYTN YTNCARACNTCNYTNTGYAGYAAYAAYGARAARGARGTNGCNGCNAGYYTNMGNTGYYTN CARTCNYTNACNMGNTCNGTNCARCARATHMGNACNGTNYTNAAYGAYAAYTCNGTNTGG AARCCNYTNYTNGARAARATHMGNTCNGGN---------------AAYMGNGARATHATG GTNYTNGCNATGGCNTGYYTNTGYAAYYTNGTNYTNGARTTYTCNCCNAGYAARGARGCN YTNATHGARAAYCAYGCNGTNGARGTNYTNTGYGGNYTNTGYMGNAGYGARGAYAAYATH GTNMGNYTNAAYGCNACNTGGGGNATGATGTCNATGTCNTAYTGYGCNTCNGARGARYTN MGNYTNACNATHATHGCNAARYTNGGNAARGAYACNATHGTNGGNMGNATHCARGAYCCN GTNYTNYTNATHMGNGARAARGCNYTNTGYYTNGTNMGNAAYYTNYTNACNGGNAARATG GAYATHGAYACNACNGTNAARAGYYTNGGNAAYGARACNATHGARGCNGTNTTYGGNATH YTNTCNGARCCNGGNYTNCCNAARATHGTNGTNGTNCARGCNYTNTGYGTNYTNAGYAAY ATGGCNGAYGGNCCNTCNTGYAARGCNTAYATGATHGGNAARACNGAYGARATHATGGCN GTNYTNAARTAYYTNCARTGYCCNGAYACNGAYTAYCARGTNCCNGTNATHCARTTYGTN AGYAAYYTNGTNGAYACNAGYGAYGAY------------------------GGNTCNTAY CARMGNATGYTNCARYTNAARAAYYTNGGNGTNCARGCNYTNYTNGARGGNYTNATHGGN ACNGGNATGGARGAYGTNGARATGMGNGCNGARATGGCNYTNAARTTYTTYGCNATGTCN ACNTAYATHMGNMGNTAYGCNAARTAYYTNAAYGARAARGCNGTNTCNTAYMGNTCNATG GCNTTYGAYTTYTGYAARGTNAARMGNGGNAARGARGAYGGNYTNYTNMGNACNATGAAY GCNGARAARYTNYTNAARACNATHCCNACNYTNCARCARCARYTNGAYGCNYTNYTNGAR TTYGAYTGYACNCCNAAYGARYTNACNAAYGGNGTNATHACNGCNTGYTTYATGYTNYTN TTYAARGAYYTNATHMGNYTNTTYGCNTGYTAYAAYGAYGGNATHATHAAYYTNYTNGAR AARTAYTTYGAYATGAAYAARAARCARTGYAARGAYGCNYTNGAYGTNTAYAARMGNTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR AGYMGNAARMGNYTNTAYCAYTGGYTNMGNCARAAYGTNGARGAYAAYAARGGNYTNAAR TGGGTNGAYAARGARGARCARATGTTYTCNATHCCNTGGATHCAYAARCAYAGYMGNGGN TGGAAYAARGARTAYTGYCARGTNTTYAARGARTGGGCNAARTTYACNAAYMGNTTYCAY GAYGGNGCNCCNGARGAYTGGCCNGGNTGGAARACNMGNYTNMGNACNGCNYTNAAYAAR YTNCCNTAYTTYGARGARATHCAYAARYTNCAYMGNATHGAYGAYGARMGNCCNTAYAAR GTNTAYMGNTTYGTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CARYTNGARTGYTTYYTNAAYCCNGAYGCNCCNGARTTY YTNCCNYTNTCNCCNGAYTTYYTNAARACNCCNCCNGGNGAYYTNAARGTNYTNAGYTGG CARGGNGCNCARGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN YTNTCNYTNYTNAAYGAYTTYCAYTCNGGNAARYTNCARGCNTTYGGNAGYAAYGCNACN TTYAAYAARATGGAYGCNATHMGNATHCARCARGARCARYTNGCNAARGARCAYTTYGAR TTYGAYYTNYTNCCNMGNTCNGCNTCNAGYMGNCARAAYACNGARGARTCNMGNAARGAR AGYAGYGARAARATGGAYAARYTNATHGAYCAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNCCNGARGCNGTNTAYYTNMGNMGNGAR AARCARCARCCNCCNACNYTNGTNGCNTCNAARCAYCCNCAYGGNGCNAGYCCNACNAAY YTNTCNCAYCCNCAYACNGGNCARGCNMGNCCNYTNMGNTAYGGNAAYGAYAAYAGYAGY GTNAAYMGNCARTCNMGNACNCARACNACNMGNCCNGAYCCNATHCCNGGNCARCCNTAY GCNGGNGCNCCNGCNCARMGNGTNGGNAGYGCNCCNYTNMGNAARATGGGN---AAYCAR GGNACNATH------MGNACNGGNGGNGTNGGNAAYMGNTCNACNGGNGARACNAGYGAR ---------TGYCCNAGYCCN--------------------------------------- TTYATGMGNCCNCAYTCNMGNTTYCAYCCNAAYTTYYTNCCNCCNATGCCNMGNCCNCCN CARGCNTCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARGARYTNGAYGGN CAYGTNYTNAARTGYGTNAARGAYCARAAYGGNAAYCAYGTNGTNCARAARTGYATHGAR TGYGTNGAYCCNGAYTAYYTNCARTTYATHATHGAYGCNTTYAARGGNCARGTNTAYAAY YTNTCNACNCAYCCNTAYGGNTGYMGNGTNATHCARMGNATHYTNGARCAYTGYACNCCN GARCARACNCARCCNGTNYTNGAYGARYTNCAYGAYAAYACNGARMGNYTNGTNATGGAY CARTAYGGNAAYTAYGTNGTNCARCAYGTNYTNGARCAYGGNMGNATGGARATGAGYACN TCNGTNGGNACNATGMGNGCNAGYTCNATHAARTCNTCNGARCCNAARGAYAARACNGTN AARGGNGARAARATHATGACN---TCNCARCARACNGCNGCNAARACNGARAGYCAYTCN AGYAARATGCARCCNACNCARGARCARYTNMGNYTNGCNCARATGATGACNACNAARGCN ACNGAYGCNGAYCCNAAYACNGTNAARCARYTNATGGAYATGACNGGNAARGGNGARGAY GTNGTNGTNATHGCNYTNCAYGAYGCNGGNAAYGAYGCNGARAARGCNGTNYTNATGYTN YTNGARGGN------GARCARGGNGARTGGCAYGARCARAAYGCNAARAARAARAARAAR ------ACNCARAARGAR---ACNGTNGTNGTNGARGARCARCARTCNGAYAGYMGNACN AAR------------GARMGNAAYTCNGAYAARAGYGGNGAYCAYCARGARTTYCAYCCN MGNMGNGGNMGNMGNAAYGGNGGNCCNCCNCCNMGNYTNGCNMGNGGNMGNGGNMGNGAR MGNGGNAAYTTYGGNGAYMGNGAYAARGARMGNAAY---ACNGTNGTNGARGAYTGGGAY AAYGARAARGARAAYGGNGAYACNGTNGCNMGNAAYGAYMGNGAYMGNAAYGGNAAYGAY MGNGGNMGNTTYMGNGGNMGNGGNGGNTTYGGNACNMGNAARCCNGGNGGN--------- GGNGGNMGN---GGNMGNTTYAAYAAYAGYAAYGAYMGNGARAAYMGNGGNTTYACNMGN CCNMGNMGNTTYGAYAARGTNAAYCCNGCNCCNACNYTNGAYGGN------CCNGARATH GAYACNTGGACNAAYGARACNGCNGARAGYACN---AAYAAYAARGAYACNGAYTGGAAY AGYTGGAAYGAYTCNTGGGTNAAYGAYGARGAYCARTGGACNGGNACNYTNGARGARACN AARGTNTTYACNCCNTCNCAYGTNAARATGCCNGARCCNGAYCCNATHAAYAAYGARCCN CCNAGYTCNYTNGGNCARMGNYTNGAYGTNGGNAGYYTNTTYGARAAYGCNAARTTYTCN AARGCNCCNGAYTAYAGYAARCCNAGYAAYGAYTCNTAYATHACNCARTTYAAYCARGCN GCNACNGARTCNATHAARAAYACNATHGGNATHGGNAGYACNTCNMGN------------ ---GCNCARATGGGNATGTCNGTNCARAAYGCNTCNGGNTCNYTNGGNYTNACNAAYYTN GGNCARACNACNGGNCARGTNCAR------TCNYTNYTNACNCCNYTNCARCARCARAGY CCNCARAAY------TCNATGCCNCAYGCNATHACNCARYTNTCNCARATHCARCARCCN ACNTCNCARTCNCCNAAYYTNTCNCARATGGGNATHGTNTCNCCNCCNAGYTCNACNAGY ACNAAYCARAGYCCNCARCCNGGN------------------------------------ ------------------------ATHCCNTCNGTNATG--------------------- ---CARCARGAYYTNTCNCARTCNACNYTN---AAYAGYATGCARCARMGNTCNAARCCN CARAARTCNAARYTNCCNCCNCCNTCNAARATHCCNTCNACNGCNGTNGARATGCCNGGN CAYATHCCNMGNAAYCCNCARYTNGAYGTNCARTTYGGNYTNGAYTTYGGNTCNGARTCN TCNGTNCARTTYGGNTTYGGNGGNGAY------------ACNACNGARACNAAYTAYTCN TCNGCNTCNAAYGGNGCNGCNACNGTNYTNTCNAAYCAYYTNAAYCARAGYCAYGTNACN CARTCNGCNGGNGAYGGNAAYTCN---GGNACNATHATGCCNTCNCCNTCNGCNGGNACN ACNAARGTNCCNTCNGGNATHGARTCNCARGTNTCNAAYMGN------CARGTNTTYCAY AAYTCNGTNTAYACNCCNCAYCARTCNAARACNGARAGYCARCCNACNGARMGNGAYCAR AAYAARGTN---GARTCNATHCCNTTYYTNTCNTCNCARYTNGARMGNAARACNCCN--- ---ATGGCNGCNCARCAYGCNACNCCNACNAAYCARAAYYTNAGYTCNGGNCCNATHACN TCNAGYAARAGYGAYTCNCCNAGY---GTNGTNGCNAAYAAYTAYTCNACNGCNAAYGGN TAY---GGNTCNTCNTAYCCNAAYCAYCARAARGCNCCNAAY---------TCNCAYTCN TCNAGYTCNCARCARCCNCAR---ACNTCNTTYCCNGGNCARTAYTCNGTNAAYCARTCN ---TTYCCNTCNTCNGGNCARAGYCARTTYCCNACNCCNCCNAAYGCNTCNCCNTTY--- CCNTCNTCNCARACNCCNCARTAY---------AAYTCN------TCNCARAAYCARTTY GCNTCNGGNCARAAYCARTTYTCNGTNGGNACNTCNACN---------YTNACNCAYCAR AAYCARTAYCCNGGN---TCNCARAAYAGYTAYGGNAAY---GGNCCNTCNCARTAYTCN GGNTAYCARAAYTCNAAYACNTTYCCNTCNCAYCCNCARTCNCARCARAAYTAYCCNTCN AAYCARACNGGNAGYAGYAGYACNCCNYTNTAYCCNACNTCNACNCARGCNGGNAGYACN ATGTAYACNTCNCARTCNAAYTCNTAYCARTCNCCNCCNTCNGGNTCNTAYCAYTCNTCN MGNGARAGYTCNAAYAAYATGACNGTNACNACNCARTCNCCNGGNAGYATGTCNTTYTCN AAYCARGCNACNAGYTCNAAYYTNAARCCNGTNGTNACNCARATGAAYTCNAGYTAYAAY TCNCARAAYTAYAAYTCNACNCCNGCNCCNATGCARCCNTCNTCNYTNGCNAAYMGNYTN GGNGARAGYYTNTCNAARATHTCNATHAARGAYTCNTCNACNGCNYTNGARAAYCAYCAR CARTCNCARTTYGARCAYACNCCNTCNGCNGCNAGYATGTCNTCNAAYGTNAGYYTNACN TCNGCNTCNAGYTCNGCNTCNYTNTCNACN------------------------------ ---------------------------------------------------GGNAARGCN CCNCCNAAYYTNCCNCCNGGNGTNCCNYTNATGGGNCARTAYATHATGGGNCARAGYACN ATHCCNCCNTTYTAYAGYTTYCARCCNCCNYTNTAYGGNTAYGARGAYGTNCARYTNYTN CARCARMGNATGCCNATGCARTCNGGNAAYTAYTAYGAYATHGCNGGNTTYCCN---ACN CCNGCNGGNACNGCNYTNCCNCCNGGNMGNGAYCARCARCCNGCNATHCCNAAYGTNCCN TTYTCNGGNACNTCNGAYTCNAARYTNGCNMGNGTNGAYGCNCARAGYCCNAAYGCNTCN AGYCARCCNCARAGYGCNCAYTCNGCNACNCARCARCCNYTNTGYAAYTTY---TAYGGN TAYTAYTAYCCNTCNATGTTYCCNGGNGCNGCNGGNYTNCARTAYCCNACNACNGTNTAY CCNATHCCNCCNGTNACNAAYGCNACNGCNCAYCCNGGNACNACNGCNACNACNCARTTY CARAARTCNTAYCCNTCNCAYGTNTAYACNACNAARGGN--------------------- ------------------------------------------------------------ ---------------TCNGGNACNAAYGARATHACNCCNAAYGCNTAYAGYAARTCNCAY GGNCAR---AAYTTYGAYAARACNGGNTAYCAYGCNGGNACNCCNCCNCCNTTYAAYATG CCNYTN---ACNGCNAAYCARACNGGNCCNATGGGNGCNCCNACNGCNCCNTAYGGNGCN CCNTTYYTNCCNATGATGGCNGCNCAYCARCCNCAYTCNCARATGATGCAYCAYGCNATH CARCARGAYTCNAGYAGYAAYAGYTCNMGNGGNYTNAAYCCNGCNGCNGGNCARGGNAAR TCNGGNACNGCNAARCCNTTYGGNTCNGGN---CCNTAYTGGAAY------GARGCNATH TCNTAYYTNCCNYTNCCNCARYTNTGGGGNTGYATHTTYTTYYTNATGYTNTTYYTNYTN GGNYTNGAYTCNATGTTYAGYATGGTNGARACNATHATHACNGTNGTNGCNGAYYTNTGG CCNMGNTTYGTNAAYMGNTGGMGNATHYTNATHTCNACNGCNTCNATGGTNGTNYTNACN YTNGGNGGNYTNYTNTTYGCNACNMGNGGNGGNATGTAYTGGTTYGTNYTNATHGAYTGG TAYATHGCNGCNTTYACNYTNYTNYTNCARGGNGCNYTNGARTGYTTYGTNGTNGCNTGG ATHTAYGGNACNGAYMGNTTYAGYMGNGAYGTNGARYTNATGATHGGNMGNAARCCNTAY ACNTTYTTYATHYTNGCNTGGAARTTYTTYACNCCNATHYTNYTNYTNGTNYTNTGGGTN GTNACNYTNGCNTTYTAYGARCCNCCNAGYTAYATGGGNTAYGARTTYCCNACNTAYGCN AARGTNTTYGGNTGGATHYTNGCNGTNGCNCCNTTYATGGCNGTNATHGTNTAYGCNGTN TTYCAYYTNAARGARCARACNGGNACNTTYMGNCARMGNYTNCARAARTCNTGYYTNCCN TCNAGYAARTGGGTNCCNTCNAARCARAGYGTNMGNGARAARTAYATGGGNGTNATHGAR YTNATGAAYCCNGCNGTNYTNYTNAARYTNMGNYTNATHGTNTAYGCNGTNYTNATHTTY TTYTCNTTYTTYATHTTYGTNGGNGTNGCNGTNATGAARGAYGARTTYCCNGGNGAYGGN TGYCCNYTNTAYTAYGAY---------MGNACNTCNGGNTTYGGNCCNGAYTCNAAYTGY AAYTAYCCNATGGCNATHTCNATHATGTAYCARYTNYTNTAYYTNYTNTTYMGNATHGCN ACNYTNGTNYTNGTNYTNYTNGGNAARTTYACNGCNGAYATGGTNYTNTTYTCNGAYATG GCNGARTTYGTNTAYGTNGTNGTNGAYYTNTCNGCNTTYTTYYTNATHTTYATHGCNGCN TGYATHYTNTCNGCNGGNACNAAYGARACNTGYGAYGAYGTNAAYTGYAAYCAYAGYACN TCN---------TAYTCNGCNGCNAARGCNGCNCARGCNGGNGCNTGGATHAGYACNTTY YTNTGGYTNTTYGTNGGNATHTGYGGNTTYGTNACNYTNTGGMGNGCNGGNAARATHCCN TTYYTNCARAGYGGNGGNACNGCNAARTCNGARGCNTCNCCNGGN---CARGAYACNAAY CARCCNCCNATHGARACNCCNCCNAGYAAYCCNGAYGAYCCNCCNMGNTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ACNATGGAYTCNACN YTNMGNTGYMGNATHMGNMGNMGNYTNTAYAAY--------------------------- AGYCAYGGNAGYGGNAARGARTCNCCNTCNYTNCCNYTNACNGARGCNTCNGTNGARTAY TTYMGNGARAGYTTY------CCNGARGARGARGGNMGNYTNGAYYTNGCNTGGGCNTCN ACNGTNTGYAARAAYAARGCNGCNTCNCCNTGYTCNATGGTNATGTCNATGYTNTAYGCN AARMGNYTNMGNCARMGNAGYAARGTNTAYYTNCARGCNATGTCNTCNTCNGAYGTNTTY TTYATHTCNATGATGATGGCNAGYAARTAYYTNTAYGAYGARGGNGTNGARGARGARGTN TTYAAYGAYGAYTGGGCNGAYAAYGCNGGNAARGAYGTNGCNGARGTNAAYMGNATGGAR GTNGARTTYYTNCAYGARATGGAYTGGCAYYTNTAYGTNAARCAYGARGARTTYYTNAAR GCNYTNGCNGCNGTNGARMGNMGNYTNGCNATGCARGARGGNYTNMGNMGNGGNTGGYTN ACNTAYACNGARATGGAYGTNYTNYTNGAYTGGGAYCCNGTNYTNGCNYTNTGYACNCAR GTNAGYGGNGAYTGYGTNAARACNYTNTCNATHYTNACNTCNGCNTAYYTNAGYAGYYTN YTNAGYYTNYTNGGNGCNACNGTNGTNGCNACNCARYTNTCNCAYCCNATGGCNAGYGCN ACNYTNTCNYTNYTNTCNYTNTCNTCNTCNYTNYTNACNCARCCNYTNGAYCCN------ TGGAARTGYTGYCCNMGNAARGTNGGNTAYMGNTGYGTNCAYACNAAYCAYAAYYTNCCN TGYTTYTAYCAYTGGAAYGGNYTNAAYAGYGCNTGGTGYTGYCCNATHTGGCCN---TAY CCNATHAAYTAYGCNMGNTGYAGYTGYGAYCARTGYGCNGTNYTNACNCCNTGGTGYGCN AAYGARGGNMGNTGYMGNCCNGTNTAYCARACNAARGGNTTYYTNGCNGTNTGY---TTY AAYGGN---TGGTGGGGNTCNYTNMGNTGG---ATHAARMGNYTNCCNCARMGNTGYTAY TGYAARYTNMGNCAYAARGAYACNTAYGTNYTNTGGGTNTTYACNATHGTNACNAAYTAY GCNTTYTAYATHYTNAAYGCNTAYTAYAARACNTTYGGNYTNYTNCAYATHCCNGAYGAY CAYTTYYTNACNACNATHGTNATGTTYAARTGYYTNTGYACNCCNGTNTAYACNTGGYTN YTNGGNATHGTNATGGAYCAYYTNGGNGTNAARGTNACNATHGTNTCNGCNACNTCNYTN TTYTGYATHGTNGCNAGYTTYTTYTAYYTNACNGTNAAYAARTGGYTNTAYYTNGTNTGY GTNGCNTAYGGNTGYACNACNTAYAGYYTNTGGTGYYTNATHTCNGCNTGYTGYGTNAAR ATHTTYGGNAARACNCAYTTYACNACNATHYTNGGNATGGTNTCNACNTCNGCNTAYATH ACNYTNTTYTCNATGCCNCCNYTNACNGARTGGYTNATHTCNTCNTTYGGNTGGTTYGTN YTNTTYACNTCNGTNGGNGTNYTNGGNYTNYTNGTNGTNYTNATGYTNATGGTNTGYGTN CCNTGYTTYYTNATHCCNGTNATHYTNTGGATHTTYCAYAARTTYATHCARCCNTGGYTN TCNAARATHTGGAGYAAYTCNGARAAYTAYGTNACNAGYAAYYTNACNTGYCCNYTNCCN CARAARAARAAR------------------------------------------------ ------------------------------TAYTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CARYTNYTNTAY---CAR ------------CAYCCNGAYGGNAARGAYATGCARATHAAYATGACNGGNTTYYTNAAY GGNAARAAYGCNMGNATHTTYGTNGGNGARYTNTGGGARCAYYTNTGYAGYGCNCARGAR AAYATHACNGGNATHCCNACNGARTTYYTNGARCARAARAARAAYGARATHAARCARMGN CARGARGARCARGARAARYTNCARGARCARYTNAARYTNAARGARGARCARATHAARGAR CARYTNYTNAARGARMGNATGGARATHGAYAARAARGAYYTNAAYAGYMGNCCNGARAAR CARACNGARACNCARCARAAYGGNYTNAARACNGCNCCNYTNGAYGARGGNGARATHGTN GAYGTNAARCCNGAYYTNCCNGGNGARGCNAAR------------GARATGAARTCNTCN GGNGAYAARGARCCNGAYACNAAYTCN---------------AARGARYTNAARGTN--- ---------------------AARGARAARGARAARGARAARACNCCNGARAARAARAAR GARCAYMGNGAYMGNGAYMGNMGNMGNCAYTCNMGNACNCCNGAYAARCAYMGN---CCN MGNTCNMGNACNCCNGAYMGN---MGN--------------------------------- ------------------MGNMGNGAYMGNGAYAARGGNMGNCAYGARMGNAARMGNACN CCNCCNMGNMGNMGNTCNMGNTCNCCNMGNMGNMGNACNCCNCCNCCNMGNMGNMGNTCN CCN---TCNMGNTCNGCNTCNCCNCCN------MGNAARAARAARTCNCCNAARAARGCN AARGAYGCNAARGAR------------MGNTCNAGYAGYGARAGYAGYTCNAGYGGNTCN GARGAYAAY---------------TCNGARAARGARACNTCNCCNGAYAARACNGGNATH CARCARMGNMGNAAYTAYMGNAARCAYGAYGAYGARAGYGGNMGNGAYTCNTCNTCNGAY TCNTCNGCNGAYGAYAARAARAARAARAARMGNCCNTCNCCNMGNMGNGARAARMGNMGN GAYMGN------------GARMGNMGNMGNMGNCCNAGYCCN------------------ ---MGNMGNATGAAYGAYTCNMGNMGNMGNTCNCCNCCNMGN------------------ ------MGNMGNATGAGYCCNATGCAYCAYMGNMGNAGYCCNTCNCCNMGNMGNMGNTCN CCNCCNMGNTAYTCNCCNCCNMGNMGNMGN------AGYCCNCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYATHGCNAAYMGNACNYTNTCNTCNGCNATGGTNTTYAARCAY GARGGNGARMGNTTYCCNMGNMGNGGNTAYTGGGGNGAYATHYTNGTNTCNCCNTAYATH ACNTTYGGNATHGARACNGARGARAARTCNTTYTTYAARAARAARAAYAAYCARCAYACN ATGACNGCNGARGAYGTNGCNGARTAYAAYATHACNTCNYTNYTNCAYGARYTNYTNACN AAYGARAARTAYGARYTNCCNAARCCNGAYGARGTNAAYAAYGARACNGARGTNAARGAY AARCCN---ACNGCNACNYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYACNATHTGGGCNYTNTTYTCNAAYGTNTTYGCNGTNCAR MGNCCNMGNGGNGTNTCNATHGARAARGCNTCNTTYTAYCARGARGGNGGNAAYTTYGTN TGYYTNTCNGAYGGNAARAGYATHTCNTTYGAYCAYGTNAAYGAYGAYTAYTGYGAYTGY GARGAYGGNTCNGAYGARCCNGGNACNGCNGCNTGYTCNAAYGGNGTNTTYTAYTGYGAR AAYAARGGNCAYAARGGNGCNTAYATHATGTCNTCNMGNGTNAAYGAYGGNATHTGYGAY TGYTGYGAYGGNTCNGAYGARTAYGAYGGNACNATHTCNTGYCCNAAYACNTGYYTNGAR AGYTAYGARAARGARATGGCNCARCARGARGTNTTYMGNAARAAYCARGARCARGGNTAY GCNGTNAARATGGARTAYATGCARCARGGNAARMGNGCNAARGAYGARAARYTNGCNAAR YTNAGYGARYTNGARCARGCNAARGGNGCNYTNACNGTNGARAARGARAAYGCNGARGCN GCNAARATHGCNGCNGARGARCCNGARAARATHGCNATHGAYGARCAYAARAARGCNTTY GARYTNATHAARGARGARAARAARAARGCNAARGARGTNCARAAYGCNGCNACNGCNTTY GCNGCNYTNGAYCAYAAYGGNGAYGGNAARGTNGAYTTYCCNGARGTNATGAARCAYACN GARTTYGAYATHAAYTCNGAYGGNACNGTNAGYGARGARGARGCNAARGARTAYYTNGAR GAYAGYGAYGARGCNGAYYTNGCNACNTTYACNGARAARATHTAYCCNAAYATHAARGAR ATHTTYAARGTNGARGARATGGCNMGNGARGCNACNGCNGGNGAYGGNGGNGARGGNTCN ACNGCNGARGCNGAYAARGARGCN---------GARGGNGGNTCNCCN---GARGAYACN GARGGNGAYGARGAYGAYGAYGAYGARTCNGAYTAYGAYATHGGN------------GAY GAYAARACNGCNTCNGARGARAARGARCCNGARTAYAAYGARGARACNAARMGNYTNGTN GCNGCNGCNGAYGARGCNMGNAARMGNTTYGAYGARGCNGARAGYAARYTNMGNGAYCAY GARMGNGARATHACNGAYATHAARAAYTAYYTNGARACNGAYTTYGGNCCNGAYCARGAR TTYGCNGCNYTNAARGGNCARTGYTTYGARTTYACNGAYMGNGARTAYACNTAYMGNYTN TGYCCNTTYGAYAARACNACNCARAARAAYAARAAYGGNGGNATHGARACNTCNYTNGGN AAYTGGGGNAARTGGCAYGGNCCNGAYGAYGAYAARTAYGAYGCNATGAARTAYGARAAY GGNCARGGNTGYTGGAAYGGNCCNAAYMGNTCNACNCAYGTNAAYYTNCAYTGYGGNGCN ACNAAYGARGTNACNGGNGCNTCNGARCCNAGYMGNTGYGARTAYCARTTYGARTTYACN ACNCCNGCNAARTGYCARAARCCNGARCCNGTNGGNATGMGNGAYGTNCAYGARGARYTN ---------------------------------------------GGNTCNGCNYTNYTN MGNTGYGARGTNCARGGNGAYGTNAAYGTNGAYTTYCARTGGATGMGNGAYGGNAARGAR YTNACNGAYATHGAYGAYATHAARGGNTCNAAYACNAAYGARYTNMGNATHTAYAAYATH GARAGYACNATHTGGMGNGGNTAYTAYTGYTGYMGNATHTCNMGNGGNGARGARGTNTAY TTYACNCARGAYGCNGTNYTNCARGTNGAYACNAGYATHYTNTCNYTNAARCCNAARGGN GARTAYCARGTNACNGAYAARGTNGCNYTNYTNATGGGNGCNGGNGAYTAYMGNGGNGAR CCNTCNYTNAARGCNCCNMGNCAYGAYGTNCARACNATGGCNACNGCNTTYMGNGCNYTN AAYTTYAARGTNGTNGCNYTNYTNGAYYTNACNAARAARGARATGATHGCNGCNATHCAY GARTTYAARYTNYTNGTNGGNGARGGNGTNTAYTGYGTNTTYTAYTTYGCNGGNCAYGGN TTYGARTCNGCNGGNCARTGYTTYYTNYTNCCNCCNGAYGCNCCNYTNGGNMGNGCNAAY GAYCAYTGYYTNTCNGCNGAYGCNATHYTNTTYAAYATHYTNYTNCCNCARMGNCCNGCN ATGTGYTGYATGATHYTNGAYATGTGY---MGNATHMGNCARGAYGGNAARCCNGAYGGN GARTAYTTY---------------------------GTNTGYTAYGGNACNTGYCARGGN TCNGCNGCNTAYGARAARAARGAYGGNGGNATHYTNGTNAGYCAYYTNAARGAYATHYTN YTNAARMGNATHGGNGTNGARGARGTNTTYAGYCARYTNMGNGARGAYATHAARGARGAY GTNTTYYTNAARGARGARCARAAYGGNGARAARAARAARCARACNCCNGARATHMGNACN GTNYTNACNMGNTCNGAYMGNTCNTTYCAYGAYGARATHGAYCCNAARGGNTAYACNACN GCNTTYAAYCAYMGNCARGCNGTNTGGGARAAYGCNCAYMGNYTNCCNGGNTCNMGNGAR ATHATHGTNAAYTTYCCNGGNTTYGAYGTNACNYTNMGNYTNGAYTTYGTNGCNGARYTN TCNAAYYTNYTNACNATHACNACNACNGTNATHGAYMGNGGNYTNGCNAARATHTGYAAY GCNCAYATHTCNGARATHCCNGGNGAYGTNGCNCARAAYTCNAARTTYTTYATGACNGAR GCNGGNACNGARACNACNTCNTGYATHAAYMGNATHGCNYTNCAYGGNGTNCARMGNYTN AARACNACNATGYTNATHAARTGGACNGTNTCNTGYATHYTNCARGAYAAYTCNAARGTN GARMGNGTNATHGARGARGAYYTNGGNTGYCCNYTNGTNTCNTCNYTNMGNYTNTGGGAR GARTAYCCNGAYYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNGARAGYYTNGTNYTNGAYCAYAAYAARATHTCNTCN CAYGTNACNTTYGCNCCNTGYCCNTCNYTNCARACNYTNTGGGTNAAYCAYAAYMGNATH CAYAAYYTNGGNYTNTTYATHAGYACNYTNACNAARTTYTGYCCNAAYYTNAARATHYTN TCNATGATGAAYAAYGCNGCNGCNCCNAGYTAYTTYAAYGGNGGNACN------TTYCAR CARTAYCARGAYTAYMGNTAYTTYGTNATHAGYCAYGTNAGYAGYYTNGARGTNYTNGAY GAYACNAARATHACNAGYAGYGARTCNTCNGARGCNMGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TCNTTYCARGAYACNYTNCCNCCN AGYGGNYTNAARGARGARCCNGTNTCNGARAARAGYYTNGAYGARYTNTAYACNAAYTGG GTNGCNGAYTAYAGYMGNATHTCNCCNAARCAYTAYATHTTYACNGCNATHACNTCNAGY YTNTTYGAYTCNTTYAARAARGTNATGGGNGAYTCNAGYAGYYTNCARACNGTNGCNAGY MGNYTNAARGARTGGCARACNAARTGYYTNTGYYTNCCNGTNYTNMGNAARGARATHYTN AAYGGNYTNYTNCAYYTNACNMGNACNAGYAAYATHYTNTCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARATHCARCCNTCNCARCCNGARGAYYTNGARCCNGTNACNGARAARAAYYTNGARACN YTNGARTTYGARYTNCARGGNATHCARGGNGARTTYGARTCNATHACNTCNMGNYTNCAY GAYYTNATHGARMGNGGNAAYGTN---AAYACNAAYACNAAYTCNCCNYTNGCNAAYGCN AGYATGTCNTCNTCNTAYCCNGTNGCNGCNTGYTCNAARAAYTAYACNCCNCCNGGNACN ACNGCNAGYCCNAAYCAYACNGCNTCNTCNCARYTNATGACNCARAGYACNCCNACNGAY TCNMGNCAYGTNTCNYTNMGNAARAARACNACNCAYTGGGARMGNGTNTCNGGNTCNGCN TGYTCNGAYTCNAGYMGNAGYTCNMGNGCNAGYAGYGTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNGCNGCNATG GAYGCNYTNTCNCARTTYCCNYTNCAYMGNTGGGARGARAGYCAYGCNGARATHACNAGY ATHAARACNTAYYTNYTNAGYCCNGAYTAYCAYYTNATHACNACNATHGAYGAYATGGCN ATHTCNMGNATHTTYYTNTTYGCNTTYGGNCAYYTNTTYTTYATHAARGCNYTNAAYGAR AAYAAYCCNGARGGNACNTCNAARACNYTNTGYCARAARTGYGARGCNTCNAAYGARGGN GAYTAYYTNGGNATHTCNTTYGARAAYACNGGNACNAARGARACNTGGYTNGARGTNCAR AARYTNCCNGTNGAYAAYTGGACNAARGARYTNGARACNATHCARGCNGCNATHACNAAR CARAARGAYGARAAYGARAARGTNYTNACNGARTTYGTNGARCARGGNGCNGARAAYGAR CARGAYGCNTCNYTNAAYGCNCAYCAYTCNGTNGAYGARACNAARACNGARCAYGARTCN GGNACNAGYGTNATHGARAARYTNGGNACNAARTTYAGYCAYCCNACNYTNGTNTTYAAR GCNAARCCN---------YTNGCNGCNCCNGCNAAYGCNTCNTCNAGYATHGCNTCNGCN GTNTCNAARGTNGAYCARGGNGARGTNYTNGGNGTNGGNTCNAAYCAYGTNYTNAGYGCN GCNCAYYTNGARTCNMGNGAYGCNATGTTYAGYCAYMGNCAYGARGARYTNYTNAARTAY YTNCCNACNCAYAARGARGARAAYCARATHTCNGTNACNTTYCAYTTYACNAAYGCNAGY MGNATGATHCCNATHGGNATGGAYCARTCNGTNCCNCCNAAYAARCCNGTNTCNGTNGTN YTNTGGTGGTCNGGNTCNCARCAYGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNYTNGGNCAYTAYYTNCARGTNTAYGARGAYTTYGTNGGN YTNACNGARGTNMGNATGGTNCARGARAARGTNGTNGAYGCNGARMGNAAYTTYYTNCAR ATHCARGARCARMGNMGNACNYTNCARCARGARYTNACNTCNGTNCARAAYGAYGTNMGN AARATHGGNTCNGARYTNGARAARATGCAYMGNACNGAYCCNTCNTAYGTNGAYYTNGTN AARAARGARCAYGGNGTNYTNYTNGTNGARAARGARATGACNGAYAAYATHAARGTNYTN GAYAARTCNGARMGNGAYYTNTTYTCNTAYYTNAGYGCNAGYGTNMGNGARAGYCAYGAR AARGARMGNGCNMGNGCNGARMGNACNAARTAYTGGTCNATHATHGGNTCNATHGTNGGN GCNGTNGTNGGNGTNACNGGNTCNGCNATHAAYAAYCAYAARMGNYTNAARGARATGMGN GCNATHGTNAARGARTCNGGNAARAGYAGYTCNGARTAYAARGAYGCNGCNGAYAARGTN YTNGCNAGYYTNTCNCCNAAYYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNCCNGCNTAYTCNACNCCNCCNGCNTGYCCN CAYMGNACNGGNYTNGARTCNAGYTCNACNGGNTCNTCNTTYCCNGCNGAYTTYGCNAAR CCNGTNCCNYTNGCNGTNGTNTCNCCNMGNMGNMGNAAYCCNTGGAAYAARACNGCNAGY CCNTGGGGNAARTCNCCNGCN---GCNCCNCCNCCNTGYTCNYTNGARGARATHATGAGY GARGARYTNGCNMGNGARYTN---------CARAARAARGARGARMGNGAYCARYTNAAR CARTGYTCNGCNGCNGCNCCNGARCCNTCNGARATHGTNTCNGCNGAYTCNCCNGCNCAR YTNACNGAYGARGARATGGCNGCNAARYTNGCNGCNGARGAYACNGGNTAYGAYCCNAAY GAYGARATHATHGCNMGNATGYTNCARAARGARTTYGAYMGNGARTAYGAYTCNCARATH TCNAARAARGARCARAARTTYAAYGGNAAYAGYAARGTNTCNATHTCNTTYGARAAYTAY AARMGNMGNCAYAAYCCNGAYYTNGARGGNCARAAYGARGARGAYGAYGAYGAYGAYTAY TAYGARGARYTNCCNCCNGARTAYCCNGCNCCNACNAAYTGGGARACNCCNCCNCCNGCN ATGGGNAARGGNGGNTAYATHMGNCARGGNAAYAGYATHATHACNAARCAYGAYAARACN GTNTGYGGNMGNMGNAAYGCNGARMGNATGATGGARTTYCCNCCNGGNTTYGGNACNGGN GAYGGNGARGGNATGGAYYTNCARYTNAGYAAYAARATHTAYAAYAARYTNAARAARCAY TCNCARTCNGARAGYMGNAARACNCARAARYTNCAYGARAARAARGAYCAYTCNACNGCN ATGAARGCNGTNGAYGARAARACNMGNATHATHATHTTYAARYTNATHAAYGCNGARTTY YTNACNTCNGTNGAYGGNGTNGTNAGYGARGGNAARGARGCNGTNGTNTTYAARGCNATH GGNGGNMGNAARGAYGAYGTNGARYTNCCNMGNGAYGTNATHYTNAARATHTAYAARACN ACNATGAAYGARTTYAARACNMGNYTNCARTAYATHAAYGGNGAYTAYMGNYTNTCNAAR GAYGCNYTNAARAARTTYAAYCCNMGNAARYTNATGMGNAARTGGGCNGARAARGARTTY ATGAAYYTNAAYAARYTNMGNMGNAAYGGNGTNCCNTGYCCNGARGCNYTNACNYTNAAR AARCAYGTNYTNGCNATGACNTGYATHGGNGGNGARAAYCCNGCNCCNAARYTNMGNGAY ACNGTNYTNTCNYTNGCNGAYYTNGARGAYGCNTAYAARCARACNGTNGARYTNATGAAR ACNATHTAYCAYAARTGYAAYATGGTNCAYGCNGAYTTYAGYCCNTAYAAYYTNYTNTGG CAYGARGGNAARGTNTGGGTNATHGAYGTNGGNCARGCNGTNGAYMGNGAYAAYGTNAAY TCNGAYTCNTTYTTYYTNMGNGAYTGYAARAAYATHTGYGAYTTYTTYMGNYTNMGNGGN GTNCAYGARGTNCCNACNGCNGARGGNYTNTTYAAYGARATHACNCAYCAYGGNATHTCN GGNGARGGNAARYTNTTYGARTCNCARGTNCAYMGNTAYGARAARGARAARTAYGCNTTY GAYTAYTTYTTYGAYYTNACNAGYGARGCNMGNYTNCARAARYTNGAYYTNGAYAGYGAY AGYGAYAGYGARGAYGAYGAYGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CARAARGAYTAYCCNYTNCCNGGNGCNTAYMGNCCNYTNGTNATH YTNCCNCARGAYGTNTCNTGGTCNCAYCARMGNTAYGAYGAYTAYACNCARCCNYTNACN YTNAGYGAYYTNGAYCAYGTNCARGGNACNAARYTN---AAR---GAYAGYGAYTCNGGN TGYATGTCNGCNGCNATHYTNMGNYTNTCNYTNCCNCARTCNTGYTAYGCNACNATGGCN YTNMGNGARGCNATGMGNGTNGAYACNTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CAYAAR CCNGTNATHAARCCNATGYTNAARYTNYTNATGGARGTNGCNGARTCNCARGARATHAAY AAYGGNGARYTNGARTTYAARYTNGTNYTNGTNYTNCAYCARATHTGYATHTGYATHTCN CARCARGGNYTNATHYTNGARAGYTTYTTYAGYACNGAYACNGAYCAYGGNCCNGCNMGN TTYYTNATHTTYTCNYTNYTNATHCCNTTYATHCAYMGNGARGGNCCNGTNGGNCARAAR GCNMGNGAYGCNYTNYTNYTNATHATGACNYTNTCNTCNMGNCAYCCNCAYATHGGNCAY TAYATHGCNAAYAAYTCNCAYTTYTGYCCNGTNYTNGCNACNGGNYTNAAYGGNYTNTAY AGYTCNYTNCCNTGYMGNATHCCNCCNYTNTCNGARGAYTGGCAYGGNATHACNAARGAR GARTCNATGAARATHCCNGARYTNCARATGTTYYTNAAYTCNYTNCARTTYTCNAAYGCN GTNGTNCARATGTTYGGNGCNAARMGNCCNYTNTTYACNGARGARCCNACNGCNAAYGGN GAYGCNCAYCCNGCNAAYGARAAYGGNAGYTCNGARMGNAARMGNAARMGNAARAGYMGN TGGAAYACNGAYAAYGAYGARAARACNGTNATHCCNGGNATGCCNACNGTNATHCCNGCN ACNYTNTCNGARGCNCARCARMGNCARTAYGTNGTNCARYTNCARATHGARGAYATHACN MGNAARYTNMGNACNGGNGARYTNGGNATHCCNTCNAAYCCNGARCARMGNTCNCCNTCN CCNGARCCNATHTAYAAYAAYGARGGNAARMGNYTNAAYACNMGNGARTAYMGNACNMGN AARAARYTNGARGARGARMGNCAYAARYTNATHCARGARGCNATGAARYTNAAYACNGAY TTYAARCCNCCNAGYGAYTAYAARCCNCCNATHGTNMGNGTNAAYGAYAARGTNATGATH CCNCARGAYGARCAYCCNGARATHAAYTTYGTNGGNYTNYTNATHGGNCCNMGNGGNAAY ACNYTNAARACNYTNGARAARGAYACNGGNGCNAARATHATHATHMGNGGNAARGGNTCN GTNAARGAYGGNAARATHGGNMGNAARGAYGGNCARCCNYTNCCNGGNGARGAYGARCCN YTNCAYGCNTAYGTNACNGCNAAYAAYCCNGARAAYGTNAARAARGCNGTNGARAARATH AARGAYATHATHAARCARGGNATHGARGTNCCNGARGGNCARAAYGAYYTNMGNAARCAR CARYTNMGNGARYTNGCNYTNYTNAAYGGNACNYTNMGNGARAAYGAYGGNYTNCARAAR YTNMGNCARATHGCNGARTGYCARACNATHGTNACNAAYACNATHGTNTGYACNGTNTGY GGNGGNACNGGNCAYATHGCNCARGAYTGYAARCARAARMGNCCNGGNGAYTCNTTYMGN ATGCARCARATGCARAAYCCNGCNGARMGNGCNAARATGGAYAGYGARTAYATGTCNYTN ATGGCNGARYTNGGNGARGGNCCNGTNCCNGCNAARTCNGAYCCNAAY------TCNACN ---------------ATGATGCCNAAYATGAGYMGNCCNYTNYTNTCNAAYCCNCCNCCN AAYCCNATGGCNATHAAYTCNCCNTGGCARATG---CCN---CCNCAYMGNCCN------ ------------------------------CCNATGCCNYTNYTNAAYMGNCCNCCN--- ---ATGATGTCNTCNTCNCCNCARGTNAAYCCNATGGGNMGNYTNCCNATH--------- ---AAYCCNTCNCARCCNCCNCCNGGNATGTCNYTNCCNCCNCCNGGNATGATGCCNCCN GGN------------------------------GGNCARCARCCNCCNCCNTCNATGGGN ---------------------------CAYCARCARAAYCAY---------MGNCCNTGG CARCARCCNTCN---AGYCARTCNCARCCNATGATGGGNGGNATGGGNCCN--------- ------------------GTNTCNACNGCNGGNAAYATGGGNATGCAYCAYCCNCCNCCN TCNATGAGYCARCCNCCNCCNCCNCCNGTNTCNTCNCAYCAYGGNCAR---TCN---CAR GCNCCNCCNCCNTGGATGCARCARCARCARCARCARCARGGNAAYATGGGNATGGGN--- ------------------------------------------------------CARCAR CARCARCARCARCARCAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNTTYGGNGTNACNMGNMGNYTNAAYTTY GCNYTNCCNAARAARCCNYTNTCNGGNAAYGGNTTYAAYTAYGTNGTNTAYTCNGGNCAR ACNYTNACNCCNGAYMGNYTNYTNCCN---YTNCCNGCNGGNCARGAYTAYAAYGTNTTY TGGTGYCAYTCNATHTAYAAYMGNACNGCNTTYMGNGARTTYATGCCNAARTCNACNGCN TAYATHTCNATHYTNMGNGAYCCNTTYCARCARTTYGTNTCNTCNGCNGARTAYTAYGGN YTNACNAGYCARATHATGAARTAYAAYCCNGGN---GGNYTNATHTCNAAYCCNGTNTCN TAYTTYYTNCARAAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATGCCNGGNGGNMGNMGNYTNYTNTCNMGNATHCARTCN AAYAGYTCNTAYTCNTCNGCNGGNAARAAYTCNAGYGGNAGYGGNAGYCAYGGNGCNGAY GAYMGNGAYGGNAAYGTNGTNCCNYTNGCNTCNATGGTNGTNYTNCCNAARCAYAGYCAR YTNCCNGAYATHCCNGGNGAYGCNAAYYTNTAYTTYGARTGYATGATHTTYGCNTTYAGY GGNATGATGATGAGYYTNCARTTYATHAAYYTNTAYAARACNGTNTGGTGGYTNCCNCAR TCNCAYGCNCARTAYGCNYTNAAYYTNTAYYTNATHGAYCCNCAYYTNGTNATHTTYATH TGYGTNATHYTNYTNGTNMGNTTYYTNATHTGYTTYGCNCARGARGTNACNAAYAAYAAR ATGYTNTAYTGGCCNYTNYTNATHGTNAARGTNGTNYTNGTNGGNGCNGCNATHGTNACN TCNATHTAYACNGGNTAYCARGTNATHATGGARCAYGGNGTNGTNACNAGYYTNTTYGTN TGYTAYCCNGTNATHATHTAYTTYGTNYTNTTYGGNYTNGCNATHAARCCNYTNTAYCAR MGNCAYYTNGCNTGGCCNMGNCCNGCNTTYGGNYTNGAYMGNCCNGCNGGNCCNACNMGN ATGAARATGAARGAYGAYGCNCCNYTNTAYCAYACNTGYACNYTNACNCCNGAYATHGTN MGNGARGARGTNGAYATHYTNAARMGNGAYTTYAAYAAYMGNYTNAARCARATHYTNTTY AAYGCNYTNACNACNTCNTTYTAYGCNACNGGNGTNCCNGTNTGGTTYTCNCARATGAAY ACNYTNTAYTAYGAYTCNTGGTGGATGTGGCARCAYGTNTGYYTNACNATGYTNAGYGCN ATGYTNATGTTYACNGTNCAYTTYYTNCCNCCNCAYTAYYTNCAYYTNYTNCAYAARAGY GCNMGNCAYYTNGGNMGNTGGCARMGNATGGARGCNMGNCAYGCNCAYATHCCNTAYAAY GCNTGGTCNGARYTNCARGTNTGGCCNCARGGNGCNYTNGTNAARCAYGTNMGNGGNYTN TTYAARGCNGARGGNATHAAYGTNACNGCNGARCCNGGNAAYAGYYTNCAYAGYMGNTTY TAYGTNYTNTTYCAYCARCCNATGMGNGTNATGAAYTGGYTNGTNYTNYTNACNTGYYTN GTNATGGCNTAYCARGCNTTYMGNYTNGTNCARAGYTCNGARTGGAAYCAYATHATHTCN YTNGCNATHYTNATGTTYTGYAAYTTYTAYACNYTNTTYAARYTNATGMGNGAYTGGTTY ATHATGGGNAARATHTAYAARGARCAYGAYTAYGTNGTNTCNAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GAYGCNGAR GTNTAYTGGMGNGTNTCNAARGCNGCNTAYYTNYTNGCNGARGARGAR---AAYYTNGGN GGNAAYCARACNAARGARMGNCAYCARGAYYTNATGATHCARGCNAARGARGCNGCNGAR AARTCNATHAARYTNAAYTCNAARTGYGGNCARGCNTAYAARTGGATGACNATHACNYTN GGNAGYYTNACNGARCAYATGCCNGTNCARGAYCARATHAARAAYGCNTAYGCNATHAAR GARAAYGCNGARAARGCNATHTCNCAYATHCCNGGNGAYGCNACNATGCAYCAYATHATG GGNMGNTGGTGYTAYTCNGTNTAYATGATGACNTGGYTNGARMGNAARYTNGCNTCNGCN YTNTTYTCNACNCCNCCNACNGCNACNYTNGARGAYGCNATHACNTAYYTNGARAARGCN GARAGYYTNGAYCCNYTNTCNTCNGTNTCNAAYGARYTNTTYYTNGCNAARTCNTTYATH GARAARAARGARTAYAARACNGCNYTNAARTAYYTNAARAAYGGNGARACNYTNAARTGY TCNTCNAARAGYGAYCARACNTCNATGAARAARATHCAYGCNYTNCAYGARCARTAYAAR CAYTAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNAAYACNAARCAYTCNTCNGGNTCNTAYTCNCARAAYCAY GAYGGNCAR------GAYGARGAYGARGARYTNYTNMGNCARATHCARATHCCNCARAAR AARAAYAGYMGNYTNGARAAYGARYTNACNACNATGAARGARAARTAYGAYGAYAARAAR CARMGNATHACNCARYTNMGNCARGAYYTNGARMGNCARAARAARAARGARGCNGARGAR ACNGCNGTNATGGARAARGCNGTNYTNCARGTNGAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GCNYTN ACNYTNAGYCCNAAYCAYGTNAGYTGYYTNGTNGTNMGNGGNGCNYTNACNMGNCCNTGG TCNCCNAARTAYCCNGGNGARCCNCCNMGNYTNAAYMGNTTYCAYMGNAARGCNGARAAR YTNAAYCCNGAYTCNCARTCNTAYTTYAAYGTNGAYAGYTTYAAYCAYCCNCAYATHYTN GAYTTYTAYGAYMGNYTNYTNYTNACNYTNYTNGTNCCNCAYACNATHACNGARATHAAY YTNACNCCNGAYAARCCNAGYAARAARCARYTNGAYGCNAGYCCNGARCARTTYMGNCCN GAYTCNTCN------------------------GCNAGYTCNMGNGCNGGNTCN---GCN GAYAARCCNGAYGCNTTYMGNTGYGGNACNCCNGCNATHAGYACNAAYACNATHTCNACN MGNMGNMGNYTNGAYTAYGGNGARGCNGTNMGNAARCAYAAYTCNMGNCCNAARACNGCN TCNGARTAYATGGCNGTNYTNGARMGNGARMGNMGNYTNMGNATGGARGCNTCNGCNMGN ATHAARTCNGCNGGNGGNGCNCCNGCNTCNACNAAYMGNAGYGTNGGNGCNAGYCARYTN CCNAARACNTCNGAYAARTGYGTN------MGNCCNACNAARACNMGNAGYACNAARTCN TTYGTNTTYGAYACNCCNGCNAAYTAYTCNATHCCNGTNTTYCARCARATGAAYATHGCN GAYGCNCCNMGNATGTAYTAYMGNCCNTGGMGNGGNGAYAARYTNCCNAARGGNGARGTN CCNCAYCCNCARTCNTCNCCNCCNTTYTAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TCNGGNTAYMGNTTYACN GARGGNAARYTNGTNCAYATHGGNATGGCNGCNYTNACNTCNGARAGYAGYCARGCNAAR ACNTAYYTNTTYGARGGNYTNGTNGGNAARGAYMGNTCNMGNGTNTGGGAYCAYATGCAR TTYTGGGARGAYATGTTYYTNGAYGCNGTNGCNCARGARMGNGAYATHATHGGNATGGAY CARMGNCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARYTNCAR ATGTAYATHCCNTAYATGTTYGGNAARCCNGCNTAYCCNATHACNATHGTNGGNCCNGAY CAYGAYAARACNAARCAYGTNYTNYTNTAYTCNAARAAYCCNAARGCNTCNGARAAYTAY YTNMGNGAYATHGCNATHGCNAAYGGNTGYGTNTCNCARYTNGCNGCNTCNYTNAAYAAR GCNGAYGTNYTNAAYAARAAYGTNYTNTCNGTNYTNAGYAGYGCNTGGAAYYTNGGNAAY GTNATHYTNMGNGCNMGNYTNCARAARCARCCNGTNATHAARGCNATHGARGARCARGAR AAYGGNAARCAYGTNATHTCNGGNAARGTNGTNGAYATHCARMGNGARACNACNGGNGGN TTYAAYAARGGNGTNGTNACNATHGARGGNTTYGAYGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MGN TGYAARAARYTNACNGGNACNYTNTAYACNYTNAARMGNYTNGCNTCNGTNCARGAYCAY MGNCCNCCNAAYATHCCNAGYATHGGNGCNAAY------CARCCNCCNTCNGARGTNGAY CCNAARAARACNYTNYTNGARAAYATHMGNGCNYTNGTNCCNGAYCAYGAYAARMGNYTN CARGARGTNGARGCNACNGARGCNGCNMGNCARMGNAARAARAARATHAAYAGYCARCAR GARGCNYTNAARTTYGGNAARAGYYTNGARATGGCNTCNAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYAARTGGMGNMGNYTNAARGGNGGNYTNTTYYTNACN TCNGTNACNGGNTGYTCNATHYTNGCNGGNTTYGGNYTNACNATGGGNATGGCNAARAAR AGYGAYCCNGARAAYTTYGCNAARGGNYTNTCNTCNTCNAARCAYYTNTCNCARACNGGN GTNGARYTNGCNACNMGNGCNYTNATGAARGCNTCNYTNTAYACNGTNACNGGNTTYGGN GTNTTYTGYTTYGCNGTNTGGAARGTNATGGGNGTNCAYAGYATGGARGARTTYMGNACN AARGTNGGNAAYTCNYTNCCNMGNYTNAARMGNAARGARAGYGARGGNMGNAAYGARTTY GCNACNATHMGNGAYYTNTTYGAYTAYATHATHGAYGARGAYAARAARACNAARMGNYTN AAR---------------------------------------------------YTNAAR ATHGTNYTNGARGCNATHCAYAARGARYTNGARACNTAYAARAAYMGNTGYYTNGGNGTN GAYACNATHGTNYTNGCNYTNAARGARTCNAARAARGARAAYGAYAARYTNTGYAARCAY ATHAARGCNACNGAYCARCARATGTCNGTNYTNCARAARMGNYTNGCNAARCAYGGNYTN CCNGAYAGYGTNAAYGTNCARGAYTCNGARYTNTTYGTNCCNGGNGCNTCNAARCARACN YTNGAYAAYYTNGCNAARGARAAYGCNMGNYTNMGNAGYYTNYTNAARCARGARGGNGGN CAYGCNGGNAARAARTCNACNGAYGARTTYGARGAYATGAARGCNGCNYTNGARGARGCN ACNTGYGARATHGAYGARYTNMGNAGYAARYTNMGNAGYCARGARGARATGAARYTNGAR ATGGTNMGNGAYTAYGARTGYGARATHMGNAARYTNGCNGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TTYGAYCARAAYTAYACNTGYCARTTYTGYAARAAY GCNGCNGAYAARYTNGCNACNTAYGCNCCNACNGAYGTNACNCARATHAARGARTTYYTN GARTCNATGAARYTNGCNTTYATHCAYAAYYTNAAYAARYTNAARMGNTTYYTNAARCAR GCNGARYTNGAYCAYTAYGCNYTNTTYMGNGCNYTNTCNTAYYTNAARAARTGYGGNTGY GGNACNYTNATHYTNMGNTTYGTNAARYTNGAYGCNGGNCCNGARACNAARGCNGTNYTN TCNGTNYTNGARAAYTTYATHACNTCNACNGGNCAYAGYYTN------------TGYCAY AGYTGY---------CARTAYGCNAARTGYGCNGAYAARTAY------------ATHGAR GAY------AAYYTNGGNGAYTGYGGNGAYGAYATGTAYTGYGTNAARTAYAARACNTTY GTNTGGATHCAYGAYTCNGGNGARATHACNGGNAARACNMGNGARTCNTCNGTNGTNACN MGNACNTGYGARGCNAARAARGAYCAYGARGARAARTGYATHGGNTGGCARAAYAAYGGN GGNGTNACNYTNAARTGYTGGTGYGGNTCNGAYGGNTGYAAYAGYGGNAARTCNYTNMGN CCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AGYGGNTCNAGYTCNATHAARACN--- ------------------GARGAYGTNAARCCNAAYAARACNATGYTNGAYAARYTNATG GCNTCNAARTCNTTYACN------------------------AAYTCNCAYGARAARTCN AARGTNCCNYTNTCNGCNGTN------CARGARMGNTAYGCNTGGAARYTNAARAARYTN AARAARACNATHAARGAYACNATHTTYACNAAYGCNGCNATHTGYGAYGARGTNYTNMGN ACNGARGARAARYTNGCNMGNGCNAAYGARGARMGNMGNTTYYTNYTNMGNAARYTNYTN CARTTYCARTCNATHTCNGAYGGNCCNACNTCNACNCCNMGNGGNAARTCNTCNGCNGGN GGNGCNGAYCARCCNTCNAARAARGCNACNAARMGNAAR---YTNAAYTCNGCNACNACN CCNGCNGCNGCNAAYCCNAGYCARACNGGN---------------------GCNGCNGCN ATGACNAGYGTNCCNGCNGTNTCNAGYGTNCCNTCNCCNGCNATGACNGGNGCNGGNCCN GARAARAARAARAARCARGCNTCNCARTCNGCNAARGARATHYTNACNTCNYTNCARGGN MGNCCNAARAARGGNAARTCNGGNGGNAARAARACNATHCCNCCNYTNATGYTNGAYTCN YTNGGNMGNCCNYTNATHCCNATGATGYTNGGNGAYATHACNYTNCAYTGYATGGGNGAR ATHGTNYTNGAYMGNCCNAAYTTYCAYTGYCCNAARTCNATHTTYCCNGCNGGNTAYTGY ATHACNMGNGTNTAYGTNAGYYTNCARACNYTNGAYGCNAARAGYYTNTAYACNTGYAAR ATHTCNGARGARGAYAGYGGNCCNYTNTTYGARATHGCNCCNGARGAYAGYTCNGAYATH GTNTTYAARGCNAGYACNCCNTCNGARTGYCAYAGYYTNYTNYTNMGNGCNGTNAAYAAR TCNMGNGGNATGGARGTNGTNCCNACNGARACNACNGGNYTNGAYTTYTTYGGNYTNTCN CAYTCNGTNATHCARAAYYTNGTNCARTCNATHCCNGGNGCNMGNAARTGYTCNGGNTAY AARTGGGTNAARTTYGARATHAAYAARACNCARGCNAAYGARAAYTTYGCNATHGGNMGN GAYGAYCCNACNGTNAGYTAYGARGCNTTYATGGCNCAYTGGGCNTCNGTNAGYCARTCN CARMGNGGNTCN------------GAYAARTCNAAYACNAGYYTNMGNTCNYTNYTNACN AAYGTNACNGGNATGAARTTYCARATHGAYCARGCNYTNGCNGGNGGNGGNMGNYTNGGN ACNATHACNCARACNYTNATHAAYGGNAAYATHACNGTNCARACNCCNATGTGYACNYTN TAYACNAARGGNGGNAGYGCNCCNTAYYTNGGNYTNAAYATGYTNGARAARATHAARAAY GTNCCNGAYGTNGCNACNATGAGYYTNAAYGCNTTYATHGAYCAYCAYGAYAGYATHAAR CARTTYGGNCARGGNYTNAARGGNTTYACNGCNATGAARAAYAGYYTNATHTTYTCNACN YTNCAYGAYGCNGGNGTNGARATHACNTCNGGNAARAAYGARAARTCNGGNGTNGCNGTN TGGGCNAARGGNGGNAARACNATGYTNGAYCCNGGNYTNCAYGTNAARATHCARGARGCN YTNCARCCNGAYTGGYTNYTNGCNYTNGCNGAYGGNGAYACNGAYYTNGARAGYGGNGAR AARMGNGCNATGAARGCNGTNGAYMGNACNYTNGAYTTYYTNGAYAGYYTNGTNGCNGCN MGNGARAARAGYGARGTNYTNAARAGYTCNAGYYTNATHGGNGCNGTNGTNGGNGGNTTY AGYGARAARCARMGNGARMGNAGYGCNAARGARACNTCNACNMGNCCNGTNCAYGGNTTY YTNYTNGARGGNTTYCARAARATHGGNTCNGARAGYGAYATHATGGAYAAYAARTCNTTY MGNGAYATHYTNTCNCARACNYTNAGYTAYYTNCCNGARGAYAARCCNMGNATHATGGAR TCNGCNTGGTCNCCNYTNCARGTNATHCARGCNTTYAARYTNGGNATHGAYGTNTTYTCN AGYGCNTAYCCNCAYYTNYTNACNGARAARGGNAARGCNYTNACNGCNGAYTTYAGYYTN TCNYTNTCNTCNTCNAGYGARAAYYTNGARAARGAYGGNYTNAARTCNGAYTCNYTNAAY TCN------GTNATHGAYYTNAAYGAYAARMGNTAYTTYGARGAYTTYGGNCCNGTNYTN GARGGNTGYYTNTGYTAYACNTGYACNACNTTYACNMGNTCNTAYATHCAYCAYYTNYTN AAYACNTCNGARYTNYTNGCNTAYGTNYTNYTNACNATHCAYAAYTTYGARMGNTAYTTY CAYTTYTTYCAYTGYYTNMGNGARGCNGCNCAYGCNAAYAARGTNGAYCARYTNGARAAR AARYTNYTNCAYCAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGACNACNGTNTGYAGYTGGYTNAAYTTYTTYTGYYTNMGNGARGTNCAYAAYAARAAR GCNGTNCARCAYMGNATHCAYCCNAAYMGNCARGCNTAYGAYGCNGTNGTNGTNTGGAAY GGNMGNGARAAYAARAARTCNAARCARGGNAGYATHAGYTTYGAYGTNATHYTNAARCCN GCNTCNGCNGARTCNCCNMGNCCNGTNYTNCCNAGYTCNCCNMGNGARTCNATGAARAAR GARYTNTCNGARGARCARATHGCNATGAARATGAARAARGCNGARCARMGNMGNAGYYTN ATHGARCARGARMGNATGGARCARYTNGCNAARGARMGNCARAARGCNATHGARGTNATH ACNAARGCNCAYTCNGARAGYGARGARTTYTCNMGNAARACNGARGARAARYTNAARMGN TCNATGGARAAYMGNMGNGARAAYMGNGARACNCARATHMGNGCNYTNCARGARMGNYTN MGNGARCAYTCNGTNAARGTNCAYATHGTNCARAARGCNGGNTCNGARATGGTNAARGAR TTYGARACNAARGCNGARAARAARYTNAAYCARAARATGACNACNTAYGARGARAAYMGN AARAAYCARYTNTGYAGYATGYTNTCNAARYTNCARGARCAYGCNAAYCAYATHAAYGAR GTNTGYGTNTCNGCNGARAAYMGNGGNGCNAAYACNGAYGARYTNCARGARCARYTNGTN CARAARATGGARAAYGCNYTNAARAAYMGNGARGARCARYTNMGNGGNATHCARGARMGN YTNGCNGARCAYGARAAYMGNATHAARGARGTNCARAARAARAAR---GTNATGGTNTCN TCNGGNCCNMGNGTNTAYAAYTGYCAYYTNTGYGAYGCNMGNYTNAGYTCNGARTTYTTY TTYMGNYTNCAYYTNGCNAARCAYAARGGNTTYMGNCAYATGACNGTNYTNTCNACNCAR GAYGGNGTNYTNGTNTGYAGYMGNTGYAAYTAYATHGCNAGYAGYAGYYTNGAYYTNGCN AAYCAYTTYTCNAAYCAYGTNACNGAYMGNMGNTTYACNTGYTCNYTNTGYGAYTAYGAR GAYCAYCAYMGNAARGGNATHMGNAAYCAYATHGCNAARATHCAYMGNGARGARGAYAAY GCNMGNGTNYTNGAYMGNGARAAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR GTNAGYCARATHMGNATHGARGTNGAYTGYTCNYTNGCNTCNAAYTGGTGYGARYTNGAY GCNGTNCARYTNGTNGGNGTNMGNGAYGGNGCNGTNGGNGCNGTNGAYGAYACNCARTTY TTYGCNGAYATGCARYTNYTNGTNAAYAAYAARYTNCAYAGYGAYGTNATGTTYAAYATH GAYAAYAARAGYGTNTAYGGNCAYAARGCNATHYTNGCNGCNMGNTCNCCNTTYTTYGCN AARATGTTY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CCNGCNTCNGCNYTNGAR TTYACNAGYGCNYTNYTNTGYCAYTAYGAYYTNATHAAYAARAARGCNCAYYTNYTNGCN CARTAYYTNGGNGGNYTNACNGAYCAYYTNMGNCARTTYMGNGTNACNTGGGARYTNYTN AAYAARCAYYTNTTYCAYTCNATHGCNCAYAAYGAYCCNGCNATHAGYTGYGTNGGNGCN ACNATHYTNGARCARYTNMGNATHGGNTCNAARCARTAYGARMGNTCNGGNGARGAYCCN TTYTGYAAYGTNMGNAARMGNYTNYTNAARTTYCARGAYGARATHTCNGTNGTNGTNGTN GTNTGG------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGGGTNCCNATGAARACN CARMGNACNCARGCNATGCCNAARCAYACNYTNTTYGGNACNGCNYTNGARAAYGTNGAY MGNGARGGNYTNAARGAYATHGARGGNMGNTAYATHCCNGARGGNTTYATHAARGARGTN CCNAAYMGNTAYCCNYTNCCNCCNCAYATHAARGARAGYYTNCCNGGNMGNGAYTAYYTN CAYACNTCNAARCARGCNTTYGARGARAARAARGGNGCNYTNTCNCARGCNAAYCARCAR YTNMGNACNAARTCNGARAARTCNYTNGCNTTYAARGCNCCNGGNGAYGGNCARCCNTCN CCNCARAGYAGYCCNMGNTCNAAYMGNCCNTCNTGGYTNTCNGARAARGAYYTNCARCAY TCNGARGAYATHAAYATHGTNGGNYTNTCNAAYMGNGGNAGYTAYAAYMGNGAYAARTAY GGNAARAARCCNCARGTNCAYAAYTAYAGYYTNATHGGNGAYGTNYTNNNNAARAARATG GAYTTYAAYTCNGCNGARATGGCNGCNAGYCAYAAYAAYTAYAAYGGNMGNMGN------ ---------GGNTGGGGNMGNGGNMGNAAYYTNCCNTGYGAYYTNATGGAR---GARAAR TCNAAYAARAARAARGCNCCNTCNAARAGYGTNYTNGARYTNCCNCCNAAYATHMGNCAY CARTTYGGNAGYMGNGTNTGYGAYACNYTNYTNTCNGAYCCNACNATHGTNTCNATHGCN YTNGARAARCARAARTCNMGNATGGGNCCNCCNMGNCCNTCNAARAARCARGARGTNGAY AGYYTNGCNGTNCARATGAAYGCNAAYTAYGARAGYYTNGGNAAYATHACNMGNTAYAAY GTNTGYCCNGGNATHAGYTCNGGNCAYAARGTNAGYMGNACNAARGCNGARTTYAAYGAY GARGTNCAYCARMGNMGNGTNCCNCCNACNGAYGARTTYMGNTAYCARMGNGAYGARYTN AGYNNNATHTGGGTNGARCARGAYGTNYTNMGNAARMGNATGCARACNCARTGGAAR--- ------TCNTCNCARCCNCCNCCNAARGCNAARCCN---------AARCCNMGNCCNAAR CCNAARCARACNCCNAAR---------GARGARGTNGTNCCN---------CARGARCCN GARATHGTNTTYGTNACNCCNCCNYTNACNCCNCCNYTNCCNGARMGNGARYTNGTNGAR YTNCCNAARACNTTYCARAARGAYGAYGARTTYTGGAGYTTYTAYGAYCAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AAR---------------------TTYTGYTGYAGYYTNTGYGAYTTYACNGTN GAYTGYCAYTAYTTYGGNAARMGNCCNCCNTTYGCNAARCARTTYYTNYTNCAYGARGAY TGYTAYATHATGAARGAYCCNTTYTCNACNACNGGNGGNTTYATHAAYGTNGGNGCNGTN TGYTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CCNYTNTCNTTYACN TCNGCNCCNATHAARATHYTNYTNTCNYTNYTNYTNYTNATHATHTCNGTNCARAAYMGN TGYGARGAYGTNATHCARTGYGCNMGNTCNTTYCARYTNTTYAARATHAAYTAYAAYATH ACNGAYYTNGARATGCCNGAYCCNCARGTNATHTGYCCNGCNGTNMGNGCNTAYMGNCAY TGYGTNAAYMGNTCNGCNTGYGGNGGNGGNAAYATHYTNTAYYTNACNAGYMGNACNGCN TTYAARAARACNACNAAYCCNTAYAARTGYAAYTTYACNTCNGGNACNATH---CCNAAR ATHCCNAARCCNTAYGTNGCNGTNCCNGAYACNTGYATGTAYCARGGNMGNAARGTNTTY MGNCAYTGYGGNYTNTTYGGNGAYCCNCAYYTNMGNACNTTYGAYGGNGTNTTYCARACN TGYMGNGTNMGNGGNGCNTGGCARYTNATHAAYAAYGAYTAYYTNACNGTNATGGTNACN AAYGAYGCNGTNGARGGNAAYGCNAAYGCNACNGCNACNAGYAARYTNACNGTNATHGTN AARGGNAAYGTNYTNTGYACNTCNAARAAYTAYCARACNTAYCARGCNGARAAYAAYAAY YTNCCNGGNAGYTTYCARGAYAGYCARGTNAGYTAYGGNCCNTAYMGNAGYGTNGARYTN GTNGARGTNGAYCCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYGCNYTNTCNTGYTCNTAYGCNCCNYTNYTNCARCAYYTNGCNTTY TAYGAYYTNGCNTGYYTNAGYAARTTYGGNTCNCCNMGNYTNCARGARATHYTNAGYYTN AGYCARCCNGGNGGNCAYCCNAARGTNTGGATGGCNGTNAGYTCNTCNACNGTNGCNGCN ATHMGNGARYTNTCNAAYYTNGTNAARGARGARAAYTGGTCNATHATGTCNAARGTNCCN GTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TTYGARGCNGTNCCNTAYMGN TTYTAYGCNGCNAGYACNGCNTAYTTYTGGGTNCAYTTYGGNYTNGTNATHYTNGGNTTY YTNATHGCNGTNGTNACNTGYATHGCNCARTGGMGNAARCCNGCNCCNTAYGGNAARCAY GAYTCNTCNACNGARAAYTGGGGNCCNGARATHCCNCARMGNYTNTCNCAYTTYYTNTCN GAYGCNATHCCNGGNGTNYTNATGTTYTCNYTNGTNTTYTTYYTNTAYAGYMGNGARGAR AGYGAYAARAARGCNYTNAAYTAYGTNTTYTAYGCNYTNTTYYTNGTNCAYACNGTNCAR MGNGGNATHATHCAYCCNYTNATHATGAARTAYAARAGYGCNAARGTNTCNYTNGGNATH TGYYTNGGNGGNGGNATHCCNAAYGTNYTNTAYCARTGGYTNATHGCNAAYCAYATHGGN GTNGCNCARTAYGAYTCNTCNTAYCCNTAYGAYCCNMGNTTYATHYTNGGNYTNATHYTN TAYGTNGTNGGNTTYATHGTNAAYMGNTGGGCNGAYTGGAARYTNMGNTCNYTNMGNGAR YTNGTNGGN------------------AGYMGNGGNTAYTAYATHCCNTAYGGNGGNYTN TTYAAYTAYGTNGCNTGYCCNAAYTAYTTYGGNGARYTNGTNCARTGGACNGGNTGGGCN GTNATGACNTGGTCNYTNTCNGGNTTYGTNTGGGCNTGYTTYGGNGCNGCNACNTTYYTN GCNMGNTCNMGNCAYAAYYTNAARTGGTAYCARGARMGNTTYGARGAYTAYCCNACNCAR MGNAARGCNYTNATHCCNTTYGTNTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATGMGNTGGTGGGTNGTNGCNGCNGGNTGGATHGTNGCN GCNGCNTCNGCNYTNGCNGTNYTNTAYGGNATHCAYGGNGAYACNACNAGYACNGAYATH CCNAGYGTNGGNGCNGCNGCNYTNTAYAAYGCNGTNGGNMGNTCNGTNTGGGCNGCNTGY GTNTGYTGGGTNGTNGTNGCNTGYAGYGCNGGNTAYGGNGGNCCNGTNAAYGCNYTNYTN TCNTGGTCNCCNTTYGCNGTNYTNGGNMGNYTNACNTAYATGACNTAYYTNATHCAYCAY AAYYTNYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TGYAARGAYYTNCAYTCNTTYGTNTGY CCNATGTAYGCNGTNATHGGNACNTGYTCNAARGGNGARTTYTGYCCNYTNYTNCAYMGN CARAGYMGNAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNAARCARATHGARTTYAAYACNATHGCNTCNGGNATG CCNGGNYTNGGNCARAARACNACNAARYTNCAYMGNYTNACNYTNAGYACNGCNGGNMGN GARTTYACNTCNAAYGARGTNCCNGAYAAYACNCCNGCNGTNCAYTTYGCNGGNGGNTTY GTNMGNGCNTGGGARYTNTAYGGNAAYCCNAAYGCNGTNATHATHTTYATHGTNAGYGAR ATGGARAARAAYTTYYTNGAYCARGGNGCNYTNGARTTYGARATHTAYTCNATHAAYCCN ACNATHMGNGTNYTNMGNAARACNTTYYTNGAYATHCAYAARATGGGNAGYYTNGAYAAY GAYGGNACNYTNTTYYTNGAYGGNGAYGARGTNGCNYTNYTNTAYYTNMGNGAYGGNTAY ACNGARGCNAAYTAYCCNTCNCARAARGARTGGGAYGCNMGNYTNATGATGGARATHTCN MGNGCNATHAARTGYCCNTCNATHCARTAYCARYTNGTNGGNGCNAARAARATHCARCAR GARYTNGCNMGNCCNGGNGTNYTNGARMGNTAYGTNAARGAYCCNCARGTNGTNAAYGCN YTNAARTCNACNTTYGCNGAYCARTAYAGYYTNGAYYTNGGNCCNGARGGNGAYGARGCN ATGMGNYTNGCNATHAGYTCNCCNGARMGNTTYGTNYTNAARCCNCARMGNGARGGNGGN GGNAAYAAYYTNTAYGAYCARGAYATHGTNGAYTTYYTNAAYAARAAYTCNGCNTCNACN GARMGNAAYGCNTAYGTNYTNATGGARMGNATHTTYCCNYTNCARCARCARAAYTTYYTN TGYAARGGNGAYGAYCCNCCNAARYTNTCNAGYGTNGCNAGYGARYTNGGNATHTTYGGN YTNTAYATHGGNACNACNGARATGGTNGARYTNGARAAYAARGARTGYGGNTTYYTNATG MGNACNAARATGGCNGGNATGGCNGARGGNGGNATHTAYTCNGGNTCNGCNGTNYTNGAY AGYYTNTTYATHGTNAARAAYTTYATHAAYGARAGYYTNAARATGGARTGYCCNAARATH ACNGARACNGAYAAYATHGCNAARYTNGCNAAYGTNATHTCNGGNMGNGCNGCNGTNGGN TAYGAYGCNAARGGNAARGTNCAYATGGTNCARGTNAAYGGNTGGACNGAYCAYGARGGN ATHAGYYTNCAYGGNYTNGCNGAYYTNYTNATHCARATGGGNGTNACNAAYGCNATHAAY YTNGAYGGNGGNGGNTCNACNACNACNATHATHAAYGAYACNYTNGTNAGYTTYCCNTAY GAYCAYTGYGGNGGNYTNAAYACNTGYGAYMGNCCNGTNTCNACNATHYTNTGYGTNCAY TAYCCNGARTGYTCNCCNMGNGAYTGYTCNAAYAAYGGNGCNTGYATHAAYGGNCARTGY CAYTGYMGNGARCCNTGGACNGGNAAYGGNTGYGGNTGGCAYGGNGTNAAYTGYTCNCAR CCNTGYCCNCCNGGNATGTAYGGNCAYAAYTGYTCNMGNCAYTGYYTNTGYGGNYTNCAY GGNGAYTGYGAYCCNCARACNGARGARTGYMGNTGYCAYCCNGGNTTYATHGGNGARTTY TGYCAYCARGARTGYCCNCAYGGNTTYTAYGGNGAYYTNTGYYTNGAYGTNTGYTCNTGY GARAAYAGYAARATHTGYGAYCAYATHACNGGNAAYTGYAGYAAYTCNACNACNGGNGAR AGYAAYMGNAAYATGGCNGARGTNTAYAARGARYTNTGGTCNAAYGTNYTNAAYTAYAGY GCNATHTCNTTYAGYTGYYTNYTNGCNAARGARAGYGGNATGTTYAAYACNYTNYTNAAY GCNGAYMGNGCNYTNACNTCNACNGARATHGCNGAYCARAAYAAYYTNAARGARMGNTAY ACNMGNGARATHYTNGGNAGYYTNAGYGTNTCNAARYTNGTNMGNYTNTCNACNMGNGCN GAYGGNACNCCNGTNTAYGAYATGGARGAYCAYGCNAARACNTAYYTNAARGAYGGNYTN TCNYTNGARTTYYTNTGYTTYAAYAARACNYTNATGGCNMGNTAYGAYAGYATHMGNGCN TGYYTNGAYAARGAYACNACNCCNGARYTNMGNTTYACNGAYACNTAYTTYGAYAAYAAR GAYGARGARGCNGAYAARTCNAARAARGARAARGCNGAYTTYTTYYTNAAYAAYATHCCN CAYYTNMGNGARMGNYTNGARAGYGGNATHGAYGTNATHGARTTYGGNTGYGGNMGNGGN CAYGTNGTNTCNCAYYTNGCNTCNYTNTTYCCNYTNAGYTCNTTYACNGCNTCNGARGTN AGYGCNGARYTNGTNGCNGARYTNCARMGNMGNTAYGGNCAYATHCCNAAYATGAARTTY AARCARGTNGAYYTNTGYGCNGTNCCNAGYTCNGTNGARTCNMGNTAYGAYTGGGCNTTY TCNGTNAARGTNATHCAYGAYYTNCCNTAYCCNYTNGARGCNYTNAARGGNATHMGNMGN YTNGTNMGNGARAARGAYAGYGTNTTYACNTCNYTNGAYGTNGCNGGNAGYGGNAAYYTN CARGGNGAYGTNGGNGAYYTNMGNGTNGCNGCNYTNTAYTCNTTYAGYACNTTYYTNTGY YTNCCNGARAGYTAYCARGGNGGNGAYAGYGARGCNCAYGGNAAYAAYATGCCNCARGAY ACNGTNGTNACNYTNACNGTNAARGCNGGNTTYGAYGTNAARGTNATHCCNTAYGAYAAR CAYATHGCNGTNTAYYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GGNTGYAARATHGCN TGGGTNGGNGAYGGNAAYAAYATHYTNCAYTCNYTNATGTAYGGNTGYGCNAARYTNGGN ATHGAYYTNAAYGTNGCNACNCCNCCNGGNTAYGARCCNGAYGCNGAYATHACNYTNCAR GCNATGAARATHGCNGGNAARTCNGGNGCNTCNTTYCARATGGGNAAYAAYCCNYTNGAY GCNGTNTAYMGNGCNGAYGCNGTNATHACNGAYACNTGGGTNAGYATGGGNCARGAYGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CARYTNMGNAAYATGYTNYTNGAYCCNGCNATH--- ------AAYYTNGTNTTYCARMGNATGTCNAARGAR------------------ATGGAR GARCAYAARGARYTNAARCAR---------------------------------AARCAR AAYGARYTNAAYGCNMGNAARTTYACNCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYAGYCARACNGGNATGMGNYTNATGGGNAARTGYMGNATGYTNYTNCARGAR AAYGGNGARYTNGGNAARATHATHTCNTCNGGNMGNACNGCNAARYTNGARGGNGARATH TCNYTNCAYAARGCNYTNGCNGGNGARATGAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNACNTCN ATHYTNMGNACNYTNTCNAARTGYGAYYTNCARMGNGAYYTNYTNACNATHMGNAAYYTN ACNTAYGARATHYTNACNYTNTCNACNAGYGGNGTNGAYGTNAARCCNGCNATHCCNGTN ATHGCNAARYTNYTNGCNCAYCCNGAYGCNTTYGTNAARMGNGTNGCNGGNGARYTNATH TCNATHCAYGCNAARGARAAYCCNGAYGTNACNYTNYTNGGNATHAAYACNYTNGTNCAR GAYTGYAARGAYGTNAAYCCNGTNGTNMGNGGNATHAGYTTYMGNATHYTNGGNTCNYTN CARATGAAYGCNGTNTCNGARGTNYTNTCNTCNTCNATHGTNAGYGGNYTNGCNGAYAAR AAYGCNTAYYTNMGNMGNAARACNAARGAYCARGTNTTYGAYCAYYTNAAYAGYYTNGAY AGYTAYYTNACNCARGCNGARTGYTTYGCNATGACNTTYACNGCNTTYGARYTNTTYMGN CAYYTNACNCARAGYATGCCNAARGCNGARMGNAARYTNACNTCNTCNGCNTGGGCNTCN ATHAARACNAAYYTNGCNMGNGARMGNAGYGARGARATHGTNTCNGCNGCNATHCAYTAY ATHAAYGCNGTNAAYTTYAGYYTNGARAAYTGYTCNTCNGAYAARTTYYTNTGYMGNGAR GAYGAYAGYYTNTAYYTNACNCAYCAYAARATHAGYGTNYTNTCNAARATGATHACNAAR GARAAYATGAGYCARATHTTYTCNGARTAYYTNTCNCAYGCNMGNACNATGAGYGTNAAR GAYGTNMGNTTYYTNGTNAARAAYGTNTCNMGNATHATHAAYGARMGNCCNGAYATGATH AGYGCNTCNYTNGAYTTYYTNAARGAYYTNYTNGCNACNGAYAARTCNGARATHATHGAR GARGTNACNCARGTNYTNCCNTCNYTNAAYYTNACNGARGAYCAYCARTGGGARGARATH YTNGTNYTNGTNGARGARAARAGYAAYTCNATHACNTCNTCNGARGCNAARTCNTCNATG ACNAAYGARCARCCNTGGGARACNGTNGGNMGNCCNAARAARGTNAAR---GARACNAAR MGNATHTCNGCNGCNMGNGARAARGARYTNGTNGCNAARATGCCNMGNATHGARGCNAAR GAYCCNATHCARYTNGAYGAYACNYTNTTYTCNGTNTTYGARAAYAARGAR---AARYTN GARGTNCCNGCNGCNGCNGCNAARGTNGARGCNAAYCARAAYGGNAAYAARAARGCNGCN AAYCCNAARAARAARAARCCNGAY---GAYAGYAARAARAARCCNAARCCNATGGAYYTN CCNACNGTNYTNTCNCARYTNAGYCCNAARGAYYTNGARAGYGTNYTNAAYAARTCNCAR TCNTAYTTYCCNAGYCAYCCNGTNATHTGGYTNAARGAYYTNGCNTCNTAYYTNAAYATH CARYTNCARAAYTGYCCNGAYCAYGAYCCNGTNTAYMGNGAYAARCCNGTNGAYTTYCCN YTNAGYGCNGTNACNGCNAAYTAYGCNAARGTNYTNCAYTCNTTYATGAARAARTTYCCN GAYCARATHYTNGAYGGNATHTAYTCNTAYGGNATHCARACNATGYTNCARGAYTCNGCN AARGGNATHCCNGTNCAYGGNTAYAARYTNTTYYTNCARYTNATHTCNCAYGCNAARCAR GAYATHGCNATGGAYAARYTNCCNCARTAYYTNGARATGYTNAARGTNCAYCAYACNCAY CCNTCNMGNTGYYTNTCNATHYTNTGGGTNYTNGGNCARTGYGGNTTYCARAARYTNAAY TAYGGNYTNAARGTNTGGYTNGAYYTNATGYTNCCNGCNYTNGARGTNMGNCARGTNGCN TAYTAYCCNGTNGARTAYYTNGARGCNYTNATGAARYTNGAYAARAARCCNAAR---AAR ------------GCNTTYGGNYTNGTNACNYTNMGNGARTAYTTYCARGTNYTNGAYGTN TTYTTYACNCCNCARTTYGCNYTNGCNGAYGAYYTNMGNAARMGNYTNGTNTCNTGYTAY CCNTTYATHMGNAARYTNGCNTAYGGNGARGARCCNTCNCAYAAYYTNMGNACNTTYTTY CCNTCNTAYYTNGCNMGNTTYTCNTCNACNAAYTCNCARCCNYTNAARAAYCARYTNYTN GARTGYATGACNCAYTGYYTNATHACNGAYAARCARTCNTTYAGYGTNTGGTGYCARYTN TAYACNAARCAYYTNATGGCNTCNGGNCAYYTNYTNAGYCAYATHAAYMGNAAYTGGGGN AARYTNTCNTCNAARYTNGAYAARAAYGTNYTNAARGARACNYTNMGNTCNTTYTCNGTN ACNAAYGARGARYTNGARGGNAAYAAYAARGCNAARMGNGGNGAYYTNAARATGTGYYTN GCNGCNACNAARAAYYTNATGTCNAARYTNGCNGGNMGNCAYTTYCCNTGGAGYTCNYTN GTNTTYTTYYTNGTNACNGTNGTNGCNGCNATHGTNATHTAYGAYGTNGCNTCNAGYCCN GGNTTYMGNYTNTCNAARACNATGCARTTYYTNGARCAYTAYMGNATHYTNGTNYTNYTN GARAAYACNTAYYTNTGYGTNAGYAAYGCNGTNACNGTNTCNATGAAYTGGYTNAARYTN AAYTTYCCNYTNTTYTTYGCNTAYGTNMGNGAYAAYATHGGNCCNTTYATGYTNYTNGTN TGGGARACNACNAARGAYTTYGTNATHAAYGCNGARATHGTNTCNMGNCCNTAYMGNGCN YTNATGATGGARAARGCNACNCAYTTYTAYTAYTGGGTNTAYGARYTNTCNCCNGARTTY TGGGTNCARTGYGGNGARTTYTCNTGGYTNGCNTGGGARGTNYTNAARGAYTAYACNYTN MGNATHTGGAARCAYTCNYTNCAYTTYGCNGGNGARGCNAAYCAYTGGYTNACNGARCAY GTNYTNACNGGNTCNTTYTCNAARCARAARYTNACNGAYACNGCNYTNTGGGGNGTNGAR CAYYTNCARAAYTGYACNTCNGTNYTNGTNTCNTGG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAY GARGTNATHAAYAARGARAARACNGTNGAR---------------------GARYTNGAR GCNGARTCNGARAGYYTNAAYYTNAARYTNGARTCNCAYACNAARAGYATHAGYYTNYTN CARACNGARYTNGAYCAYYTNTCNAARGARAARCARTAYYTNAARGAYGTNCCNGARMGN GAYATHATG---GCNGTNAARATHAARCARYTNGARATHGARGAYTCNYTNTTYMGNAAR CAYYTNGGNATGGARATHMGNAARGTNAARGGNGGNTCNYTNCARGTNGCNTTYAGYCAR ATHGAYCAYAARCARCCNAAYTCNYTNTTYYTNTTYTCNYTNAARYTNGAYGARAAYMGN AARTAYATHGTNTCNGAYTGYAARCCNAGYATHCCNGGNACNGGNGARGTNGTNGAYMGN YTNAAYGTNGAYAAYGAYTTYCAYAARTTYATGCAYACNATGMGNCARAARTTY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNAARMGNMGNTAYAGYGAYGTNYTNGAR---GAYCCNTAYMGNGGNCCNCCNGAY TTYATGGARGCNGGNGTNMGNGGNTTYYTNGTNACNACNATHCCNGAYMGNGARGARCAY GCNYTNGAYGARGCNGTNAARGCNYTNMGNAARGCNTGYGTNAARYTNTAYGGNGGNATH MGNCCNYTNAARAARGARGAYGCNTCNTTYGCNAARGGNTAYGTNATGATHGAYTTYATG AAYCCNACNAARGTNAARTCNYTNCCNCAYCCNGAYGCNGCNAAYCARACNGARGARGAR AARCARGAR---------ACNGARCARGCNCARGARGARAARGARCCNGAYACNATGGAR GARGARAAYAARGARGCNGCNGARGAYACNAARACNGARGARGARGCNCCNGTNAARGAY GARACNGARGARAARGCNGARGGN---------GARGGNGARGARGGNACNAARGARCAR GGNGARGGNGARGCNAAYGCNGARAAYAARGARGAYAARGARAARGCNGCNGCNGCNAAR AARGARGARGARGARGCNAARAARAARAARAARAAYGARGARMGNGCN------------ ------------------------------------------------------------ ------------AARCCNCCNYTNATGYTNGCNCCNAAYAARTTYAARAGYTTYMGNACN GARYTNMGNAAYATHATGTTYATHAARTCNGAYGTNGCNGAYCCNGTNGARGTNGCNACN ACNGTNTTYGAYATHATHYTNCARMGNAARAAYATHTAYACNGAYTGYGTNAAYCARYTN YTNCCNGTNCARGGNGTNTGYGAYAAYGAYTAYAARGARYTNGARATHATGTGYMGNMGN GTNYTNGCNCCNTAYGTNGGNGARCAYYTNGARGARGCNCCNAGYTTYGGNGTNATHYTN GTNGAYAARYTNTGYGAYCCNGGNTCNGARGTNYTNCCNGARGTNGTNMGNAGYGCNGTN TGGTCNYTNAAYCCNYTNGCNTAYCARTGYGCNCCNTGGAGYGARCCNGAYGTNACNATH CAYYTNGARATHATHGGNAGYAARATHATHYTNAGYGCNATGACNCARTAYATGAARTAY MGNCARTAYAGYCCNTTYGCNYTNTTYGAYATGGGNGTNGGNCARCCNCARGAYGARAAY ---------------------------------------------------AARATHYTN MGNGARATGGARGARGARAARGARMGNGARGCNGCNGARAARGARMGNMGNMGNYTNGAR TGYYTNCCNAARAARAARAARCARAARGAYGGNGAYAARAARCARGGNTCNGARAARAAR AARAARACNGAYAARTCNGARAARAARTCNGARGARGARACNACNGARGARGCNGCNGAR GCNGGNGARGGNAARGARGARGARGCNGCNCARGARGGNGCNACNGARGAYGTNGCNGAR CCNGCNGARGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CAYGARAAYAGYAARTTY ------------------------------------------------------------ ------------------------ATGCARAARYTNMGNAARGGNATHTCNCAYAGYCAY AGYGTNMGNYTNMGNCARCAYAGYCAYGTNYTNTAYGAYAARATHACNGARATHATHAAY TCNGGNGARYTNTCNCARGAYYTNTTYGAYAARCARGTNGCNATHACNGCNGTNCARATH CAYAARGAYATGAAYAAYYTNAAYGTNTAYTGGGAYGCNGAYMGNYTNGAYTGGGARGAY GTNGARCCNATHYTNCARGCNAAYAGYGGNAARYTNMGNAGYYTNYTNATHTCNTAYCAY GTNYTNGGNMGNATHCCNCAYATHGCNTTYGTNAARGAYAARAGYCAR---GTNAAYYTN GCNGARYTNGARCARYTNTTYGCNAARGCNGAYTAYGGNCCNGAYTAYATHCCNGGNAAR ATHCARACNGAYGTNGAYGARCAYAAYGAYATHACNGAYMGNYTNTGY------CCNGAR TCNGAYCARGARATHGAYAGYTTYMGNGCNCARAGYATHAAYTCNYTNCAYAAYTCNGAY AARMGNAARGARCARGTNGTNCAYTCNACNCAYTAYAGYTCNGAYAARGAYTCNTTYYTN AAYCARGAYAARMGNGGNYTNCAYTTYGTNAARGARGGNYTNGAYTTYMGNTCNGAYGTN TAYGGNYTNAGYMGNGGNGARATHATGAARAARGTNYTNGCNAARAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TTYTTYGGNGTNAARMGNYTNTTYTGYTCNAARGGNYTNAARTTYCARAGYAGYGGN GTNTTYATHGARTTYCCNGTNATGYTNYTNACNGGNYTNYTNTCNATGCCNYTNGGNGTN YTNCARTTYGTNCCNATHTAYCAYCCNYTNCAYGAYTCNYTNGGNATHCAYTCNGARGTN TGYGTNTTYYTNYTNYTNGGNTTYTAYATHYTNGTNGTNTGG------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGACNCCNAARGAYTGGYTNAARGARATHCAR TTYTAYCARATHGCNYTNGTNTAYATGTGYTCNMGNYTNTAYGTNAAYGTNAGYCARGTN TAYTTYGGNYTNTAYYTNACNGARACNGTNCAYGCNGAYAARAAYMGNATHGCNYTNYTN CCNYTNGCNTCNTAYGGNGGNAGYATHGCNGCNTCNYTNYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTNAARGTNATHYTNTTY--- ------GAYGARGARGAYYTNCCNCCNGGNGTNMGNAARCAYAAYMGNTGYCAYAGYAGY AGYGARTCNGAYTCNGARGAYGARAARGAYAARAARCCNACNGARAARGCNTCNGAYTCN GAYTCNGAYGGNTCNACNAARAARGARGGNGARATHGCNAARCCNGARGAYCCNGCNTCN ACNGCNAARGARAARGAYGARGGNTCNGCNAARACNAARMGNAGYMGNTCNMGNTCNGGN TCNMGNTCNAARTCNMGNTCNMGNTCNGCNTCNCCNAARAARMGNMGNTCNTCNGARAAR AGYAGYMGNMGNTCNMGNTCNMGNTCNMGNGAYMGNMGNCAYAARAARGAYMGNAARMGN MGNTCNCAYMGNTCNMGNTCNMGNGARMGNMGNMGNTCNMGNGAYMGN------AAYMGN CAYAARAARGAYCAYMGNMGNAGYMGNAGYMGNAGYMGNGAYMGNMGNGAYMGNCAYMGN GAYMGNAGYAGYMGNGAYAARMGNMGNMGNAGYMGNAGYMGNAGYMGN------------ ---------MGNAGYMGNAGYMGNGAYMGNMGNMGNAGYTCNMGNAGYCCNAGYCCNGCN GGNAAR---------ATHATHAARTTYGGNGAYAARGTNATHAARCCNGGNGCNAGYTTY GGNMGNCCNAAYTCNTCNACN------TCNAARCCNYTNACNTTYAARGARAARATGMGN CARGARYTNATHCARGCNATHGARGAYGGNGCNGAYACNACNAAYAGYGTNYTNGCNAGY AARGGNTCNACNYTNTGYACNCARAGYGCNGGNATHCARCARCAR------GCNCCNAAR CCNMGNGGNCCNCCNGTNCCNYTNATGGAYGCNATHATHACNACNGCNATHACNCCNGCN GGNACNACNATHACNCCNTCNGARGCNGTNATGCARTCNATGYTNGCNYTNCARAARCAR ACNACNGARAARACNGGNATHGARATHCCNAARTAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGCNCCNGTNCCNGAYGAYGAYCAR GARAARCARCCNCCNGGN---GAYGAYTCNGARYTNAAYTCNTTYTCNATHCCNAAYYTN ACNATHACNATHGAYTCNGAYTTYAGYGAYGAYGAYAAYGARAAYTAYCCNGAYACNGCN ------GGNTAYACNYTNYTNCCNCARGARCCNGGNAAYTTYGARAAYGARGAYGAYAGY GAYATH---GARAGYGAYTTYCARAAYGAYGCNATHGGNAGYYTNGGNATHAAYAAYTCN GGNYTNAAYGGNCARTCNACNGCNACNTCNATHYTNGAYAAYYTNGCNGARAAYGTNATH CARTCNGARGCNGGNGCNGCNGCNCCNACNGTNACNGGNTCNATHACNTCNYTNCAYCCN GARTTYYTNGCNAARTAYCCNGAYGGNAARGTNCCNGCNTAYATGCARGTNCCNGAYATH CCNCCNGAYAAYAAYGAYTCNGTNTGGAARCARAARAARACNGAYAARCAYGTNCAYCCN YTNAGYTCNGCNGARGARAAYACNATHYTNAARGCNATGTCNGGNTTYTCNYTNCCNATG GARAAYATHCCNGAYTGGGCNAARMGNATGTCNGAYGARCARTGGGAYCARCAYATHGTN CARCARATHAARTCNGARCAR--------------------------------------- ------------------------------------------------------------ ---------------------CCNATHMGNGTNGCNGCNTTYAAYATHAARCAYTTYGGN ACNGGNTAYATGAARGAYAAYGTNACNGTNCCNYTNACNATHGCNATHYTNGAYMGNTAY GAYATHGTNYTNGTNCARGARCCNMGNGAYAARTGYCAYTTYGCNYTNMGNGAYYTNAAY CARMGNYTNTCNGARGCN---TCNGGNTGGGAYTAYGTNTCNAGYGARMGNYTNGGNMGN ACNTCN---TAYAARGARCARTAYGTNTTYTTYTAYAARYTNYTNTCNGTNMGNCAYATG GGNAGYCAYCARGTNCCNGAYGCNGARMGNGAYGTNTAYGARMGNGARCCNTTYGCNGTN GAYTTYGARTTYAARTCNGTNTCNAARAAYGTNACNCARMGNATHGTNYTNATHGCNYTN CAYGCNAARCCNGAYAARGTNAARGAYGARYTNGCNCARYTNAAYGTNACNATHMGNGAY GTNGCNGARAGYTCNCCNAARGCNGAYGGNGTNYTNGCNATGGGNGAYTTYAAYGCNGGN TGYACNTAYYTNAGYYTNAARGARGARAARACNYTNGAYYTNTTYACNAGYGAY---GAR TTYAARTTYYTNATHAARAAYGAYGCNGAYACNAAYGTNAAYGGNAARACNGCNTGYGCN TAYGAYMGNATHGTNYTNTAY--------------------------------------- ------------------------------------------------------------ ---------------------TTYAGYATHAAYYTNTGYGTNGGNCCNACNTAYGAYCAR GAYTGYGCNYTNCAYTTYAAYCCNMGNYTNGAYGAYAAYCARGTNGTNMGNAAYCAYAAR CARGGNGGNAAYTGGGGNCARGARGARACNAGYGGNGGNAAYCCNTTYMGNMGNGARCAY CCNTTYGARGTNCAYATGAARGTNAAYCCNCAYGGNTAYAGYATHACNGTNAAYCAYMGN CAYTTYTGYAAYTTYAAYCAYMGNYTNCCNATGGGNAGYGTNCAYTAYATHTAYATHGAR GGNGAYGTNGCNATHAAYAAYATHCARTTYMGNGGNGGNCAYCAYGGNAAYCAYGGNCAY CAYGGNCAYCARGGNCAYCAYGGNCAYCAYGTNCCNTCNTAYCCNACNGGNAAYGCNATH CCN---CCNCARGTNTAYCCNCCNGCNCCNGCN------CCNYTNCCNTCNTAYCCNCCN TCNGGNACNCCNCCNATHTAYAAYCCNCCNGTNCCNTTYACNTCNCCNATHCCNGGNGGN ATGTAYCCNGARAARATHYTNTAYATHCARGGNATHCCNCAYCCNAAYGCNAGYMGNTTY ACNATHAAYYTNCARTCNGGNCCNTGYGARTCNGGNGAYTAYYTNYTNCAYTTYGAYGTN MGNTTYAAYTTYGGNGAYACNMGNAAYGCNGTNGTNMGNACNCAYAARCARAGYGGNAAY TAYGGNCCNGARGARMGNGAYGCNCCNTAYTTYCCNTTYTGYCCNAAYGCNATHTTYGAR ATHATGATHYTNTGYAARCCNAGYAGYTTYAARGTNGCNGTNAAYAAYCARCAYTTYGTN GARTTYTTYCAYMGNATHCARCCNCCNAAYATHGCNAAYCAYYTNAAYGTNACNGGNGAY GTNAGYYTNACNCARGTNMGNTTYCAR---------TTYATGCCNAAYTTYYTNGTNAGY TCNGGNACNGGNYTNACNCCNACNYTNACNCCNACNACNYTNGCNACNATHGARCARTCN TTYYTNGARATGCARCCNGTNTCNGCNMGNGAYCCNGTNACNCARAGYGGNTTYGTNCCN CCNGTNGTNGARCCN------GCNCAYAGYGCNGAYCAYTCNCARGAYAGYTTYGCNAAY TCNTCNTCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TGGCARATGCARYTNMGNCARGARATGAARGARGAR YTNYTNAARAARAARMGNAARGARGARATGGAYAARACNYTNAGYACNGTNACNAARMGN ATHCAYGAYGCNAAYMGNYTNATGGARACNATGACNGCNYTNGARAARYTNMGNYTNATH MGNCARGAYGCNGCNAARAARMGNGGNGAYAGYGAYATHGGNGARTCNMGNCARAGYTTY GARCARAARATHGCNGAYATGACNMGNYTNGTNAARTCNCARYTNGARGTNTAYAARGAR GARGARCARCARYTNMGNAARGCNYTNACNTCNGARCARGAYGARACNAGYMGNAARGAR AARCARYTNCARGARGARMGNGAYGARAARGARCARCARCARAARGAYGARGAYYTNMGN GCNATHYTNTTYGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARTGYTTYCCNGTNAGYYTNGGNGGN AGYMGNGAYGARYTNGGNYTNGGNACNACNGTNAARACNMGNGCNTGYGAYCARYTNMGN TGYACNGCNTGYGAYTTYMGNGTNTGYTAYTTYGAYGAYTTYTCNTGGAARAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNGGNCAYMGNGTNAAYATHTAYCCNACNAGYCAYGAYGGNGTNAGYTAYTAY AGYAAYTCNGGNGARCCNCCNGGNCARAARGGNGCNTAYATHCCNGCNTCNGGNTAYGAY AARCARGARAGYAARTAYAAYTCNTCNMGNGGNGTNACNAARCAYGARTGGAARACNAAY YTNMGNGCNATGGTNCCNATGCCNCAYMGNMGNTGGGCNAARAGYTTYATHMGNGAYTGG MGNGTNGARAAYYTNAARAAYGCNACNAGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYYTNATHTTYYTNYTNGGNCCNCCNATHTTYGAYAARACNAGY TAYYTNCCNAAYGGNGTNYTNAGYACNGAYTCNGTNTAYATHGTNCCNYTNTTYGAYGAY AAYCCNACNTTYGGNYTNMGNGAYGTNTCNGTNMGNATHATHGCNGARYTNMGNAARGAY AARCARGTNNNNGTNGARGARGAYYTNCAYTCNCARAGYTTYCAYAARTGYGTNMGNGAR ACNGTNAARAARAARATHCCNCAYTGYMGNGTNYTNGTNGTNAARATHACNCCNATHCAY GGNCAYYTNCARATHYTNTGGAGYCAYATGAAYGCNCAYGGNMGNGAYYTNYTNCCNAAY TGYTCNTGYCARAARGARAAYGTNTAYTCNAARCARYTNYTNCARTCNCCNAAYCARCCN GTNGAYTAYTTYCCNGAYTTYGCNGAYTCNTCNGARCAYTCNGARAAYYTNGARATHATG GAYATHAARGCNGARTTYCARGTNCARACNGGNTTYAARYTNCARGTNCCNGCNYTNYTN GTNCARTGGGARGCNGTNGTNACNGAYTCNGGNGGNYTNCAYAARGAYTTYTGYGAYGTN TGYAAYMGNTGGGCNAARTCNAAYACNGAYGGNMGNGTNATHYTNATHMGN--------- GAYMGNAARAARGAYAARATGTCNCAYTCNAARGGNGCNGCNAAYYTNMGNACNAGYYTN AARGARATHGCNATGACNATHTCNMGNCCNYTNTTYGTNGTNCARYTNGCNCARACNAAY CCNAAYAGYTTYTGYYTNCCNCCNCAYCCNGGNATHGTNGCNTTYYTNCARACNMGNCAY TTYATHGAYGTNCAYGCNAARCAYACNYTNTAYYTNTAYGARTCNGGNGAYCAYATGMGN ATGGCNCARATGGCNGGNATHAARTAYYTNAARATHAAYAARGCNTAYMGNAAYACNCAY AARGCNYTNTTYAGYYTNTGYATHAAYTCNCCNACNCCNCCNATGTTYAARGAYYTNAAR GTNGTNAARGAYTGYAARGAYGARATHCCN------ACNGTNCCNYTNYTNAAYGARYTN MGNACNAGYGGNGARGAYAAYATHGTNGCNYTNAARCAYAARAAYGGNYTNGARGARCAY GGNTAYTTYCCNGARTTYGARGARTCNYTNMGNTTYCARGARTCNTTYGCNAARCAYGTN ACNCCNGTNGGN---------ATHCARGGNAAYAARATGGTNGCNGARGARACNGGNATH TTYTCNGAYTCNGAYCARTCNGARTGYMGNAARACNGTNACNTGYACNMGNAARCARTCN ACNTCNYTNCARAAYYTNCCNTCNTGGATGAAYAARMGNYTNAARMGNAARTCNACNGAR TCNTCNYTNTCNGGNGTNGARAGYGAYGAR------TCNTCNTTYMGNTAYCCNAARACN GTNTAYATHATGAGYGARAARGARYTNCARGARATHGCNTTYCARGTNATHAAYCARGCN GGNMGN------YTNAAYMGNGGNMGNTGYGGNCAY---AARACNATHCCNTTYYTNAAR CARTGYTGYMGNTCNGCNTCNGGNGCNAAYTCNTAYTAYGTNYTNYTNCCNGARGTNCCN CCNGAYACNCCNGARACNAAYGCNYTNATGMGNATHGAYCARYTNCCNCARTTYTCNCAR ATHACNCCNAAYYTNTGYGTNTCNGCNTGYGCNAARYTNGCNATHGARTAYGARACNAAR YTNGARAARCAYATHGAYACNYTNAARGAYACNAARACNGARAARACNTTYGARAAYGTN TAYAAYCCNYTNGARGARATGGCNGTNCCNYTNAAYACNGCNTGGGCNACNACNAAYAAY YTNAAYTAYGTN------TCNGAYGAYTTYMGNAARGCNTTYTCNAARATHCAYCCNCAY GTNGARMGNGTNAARAAYGARMGNTGGGTNAGYCARCCNYTNTAYTAYTCNTTYGARGAR YTNAARGCNAAYAGYGCNAAYYTNACNGARTAYCARAAYMGNYTNGTNAGYYTNTAYYTN YTNGARGGNAARYTNAAYGGNGTNCAYYTNTCNGCNGARGARAAYACNAGYYTNGTNGAY MGNYTNAARYTNATHACNAARGARTCNCAYAAYTTYMGNAAYAARGTNMGNATHTGYACN GAYATHTTYACNCAYGAYGTNGTNAAYTTYAGYATGYTNGARGARATGCCNTGGCCNYTN YTNGCNCARATGTCNACNGAYMGNTCNAAYCCNACNMGNGGNCCNTGGMGNGCNACNYTN CARCCNTCNGTNTAYCARGCNATGATGACNTAYTGYAGYCAYMGNYTNACNMGNTGGAAY YTNTGGAAYGCNTAYCAYAAYMGNGCNTCNCAYATHCAYGCNAGYCARTAYYTNAAYAAY AAYAARYTNATHGARAGYYTNMGNTCNTAYMGNCARGAYGTNGCNGGNATGYTNGGNTAY ACNAAYTTYGCNGARATGTCNATGGARACNAARATGGCNGAYTCNGTNGARACNGTNYTN AGYATGATHGARACNYTNMGNTCNMGNTTYGCNCCNGTNGTNTGGGARGARATHGCNCAR YTNCARCARTTYGCNACNTCNGARGGNTTYGARCAYTCNYTNGARATGTGGGAYYTNAGY TAYTGGACNMGNMGNCARMGNGARCAYYTNTAYAGYTAYGAYAARAAYGCNGTNAARGAR TAYTTYCCNGTNAAYACNGTNYTNYTNGGNYTNTTYGAYYTNTGYACNAAYYTNTTYGGN GTNAAYTTYGARGARGTNACNCCNGAYGTNGARGTNTGGCAYTCNGAYGTNMGNTTYTTY AAYGTNYTNGAYGAR---AAYGGNACNCAYATHAGYTCNTTYTAYTTYGAYCCNTTYGAY MGNCCNGGNAARGTNTCNTCNGGNCAYATGGAYTCNGGNMGNGAYAAYAGYGARYTNYTN GGNACNTGGCCNTAYTCNTAYYTNTGYYTNAARATHCCNMGNCCNACNTCNTCNTCNGAY CCNGCNYTNATGMGNTTYGARGAYGTNGARACNYTNTTYACNGARTTYGGNCAYGGNYTN CARCARATGYTNACNMGNGTNCCNTTYAGYGARATHGCNGGNCARAARAAYGTNGARTGG GAYGCNGTNCAYGTNTGYGCNAARTTYATGAARMGNTGGYTNACNGTNCCNAGYGTNGTN AARAAYYTNAGYGGNCAYTAYAGYTCNGGNCARCCNATHCCNGAYGAYATGYTNTCNGAY ATGYTNAARGCNTCNCARCAYTGGAGYAAYTTYGARACNATGTAYCARYTNTAYGTNTCN GCNTTYGAYATGGARATHTAYATGACNAAYACNCAYTGGTTYAGYATHATGAARCARYTN TGGGARAGYTTYATGCCNYTNCCNYTNAAYGGNGAYGAYAAYYTNCCNTGYTCNATGYTN CCNATHTTYTGYGARYTNTAYCCNGCNGCNTAYTAYTCNCAYAARTGGTCNGARATGATH GCNGCNGAYYTNTTYTCNGCNTTYGARGARGCNGGNYTNGAYAAYCCNGARCARATHCAR YTNYTNGGNAARMGNTTYMGNGAYACNTAYYTNTCNYTNGGNGGNGGNGTNCCNTCNAGY GARGTNTTYMGNMGNTTYMGNGGNMGNGAYCCNTCNACNCARGCNYTNCARCCNATGGAR AAYAAYAAYGCNATHGCNGCNAAY---ATGGARAAYGAYGAYGCNAARATHGTNAARGTN AARCCNACNGCNGAR------GARAAYGARAAYGAYAARAAYMGNGGNTAYMGNAAYAAY MGNMGNMGNCCNMGNAAYGAYGTNAAYCCNGARGAYGARACNGGNAARGCNGCNATHMGN MGNAARATHTGGGAYAGYYTNGARGAYAAYAAYYTNGTNTCNCCNCCNMGNCCNTGYCAY TAYMGNATHCCNAAYTTYGARGGNGCNGCNGARGCNGCNGAYAARYTNAARACNYTNGAR GARTTYAARAAYGCNMGNACNGTNAARGTNAAYCCNGAYAARGCNCARGARAAYGTNMGN TTYYTNGTNYTNGARGCNGARAARGARYTNGTNYTNYTNTCNCARAAYCAYAARGAYYTN ATGGTNCCNACNGCNGARYTNAAYTCNGGNYTNYTNAAYMGNGTNAGYGCNCCNGARGGN TCNAAYAARGARGARYTNAARCAYTGYTGYACNACNCARGGNGTNAARGARAAYAGYCAR GTNATHGGNYTNGAYGAYAARGTNAARYTNGAYYTNATHTTYGTNGGNAGYGTNGCNGTN TCNMGNAAYGGNTTYMGNATHGGNAARGGNAARGGNTAYGCNGAYYTNGARTAYGCNATG ATGMGNACNATGGGNGCNGCNGAYGCNAARACNGTNGTNGTNACNTCNGTNCAYGAYTCN CARATHGTNGAYATHCCNGARGARYTNGTNGGNGARCAYGAYGTNACNGTNGAYTAYATH YTNACNCCNACNGARGTNATHAARACNAAYTGYAGYMGNGCNAARCCNACNGGNGTNACN TGGAGYCAYYTNGARATHAAYAARTTYTAYCARATHCCNGTNYTNMGNCARYTNMGNAAR ATHGARCARGARAARGARAARAAYGTNATGYTNAARGAYCARAARGCNGARGAYGARGAY CCNGTNGAYAAYATGGARCCNCCNMGNCCNMGNMGNTAYGTNMGNTAY---TAYCARAAR GAYGGNTAYMGNGGNMGNGGNMGNTCNTAYGGNMGN---TTYMGNMGNGGNGGNAGYMGN MGNMGNACNGAYAAYGGN------GAYGGNAAYMGNGARAAYGTNGAY------GARGAY TCNGGNGCNGAYGGNGAYAAYGARGGNMGNGGNGGNAAYMGNMGNCCNGGN--------- AAYTAYMGNAAYMGNMGNTTYMGNMGNGGNGGNGGNGGNCARACN---MGNGCNTCNGAR TCNGARCAYAGYGAYGGNGGNGCNGAYGGNAAYMGNGARGAYGGNGARGAYMGNCCNGCN MGNMGNTAYAAYAAY---AAYMGNMGNMGNTAYAAYCCNAAY---TAYMGNMGNMGNMGN TAYGAY---------AAYMGNMGNGAYAAYMGN------GCNGAYCAYTCNGGNAGYGAY GGNGARGCNMGNCAYTCNGGNGAYGARGAYGGNGARGGNMGNMGNCCNCARMGNCARMGN TTYMGNGTNAAYCARGAYGCNGTNGTNTTYGTNGGNGCNYTNTCNMGNAAYYTNMGNGTN AGYGARYTNAARACNGARYTNMGNAGYAAYAAYGTNAAYCCNATHMGNYTNYTNTGGMGN GGNGGNMGNGGNTAYGCNTTYYTNTTYTTYCCNGARACNGAYAAYGCNAARGAYGCNGTN AAYYTNYTNAAYGGNMGNGARATGAAYGGNMGNGARATGAARGTNGARATGGCNAAYATG GAYMGNGARMGNMGNMGNTCNAAYMGNAAYGAYMGNGGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGCCNGTNAARMGNGTNGTNGAYAARTCNGGNMGNGGNATH TAYYTNGTNCCNTTYMGNGAYATHTAYATHTCNCCNCARTTYAAYGARCCNGCNGTNCAY ATGATGGAR---------GAYTTYCCNYTNMGNGARGAYGAYGTNATHYTNGTNAGYTAY CCNAARACNGGNTGYCAYTGGGTNTGGGARATHATHMGNATHYTNGTNACNGGNAARATH GTNAAYGAYGGNAARGAYAARTGYAGYYTNATGATGGARTGGAAY---CCNCARGARGAY TTYGCNTCNYTNCCNAGYCCNMGNYTNYTNAAYAAYCAYATHCCNTTYGCNATGCARCCN MGNGAYYTNYTNATHAARAARCCNAARGTNGTNTTYYTNTAYMGNAAYTTYAARGAYGTN GCNGTNTCNTTYTTYCAYCAYCAYTCNGGNATHCCNGCNTAYGARTAYAAYGGNGAYAAY TTYCARGCNTAYGTNGARMGNGTNGTN--------------------------------- ------------------------------------------------------------ ------------------GAYGGNYTNGTNGARTCNGGNAAYCCNTTYACNTTYACNMGN GAYTGGGARMGNGGNATGGARMGNAAYAGYGAYYTNCCNGTNTTYTGYTGYGCNTAYGAR GAYATGAARAARGCNCCNAARGAYCARATGMGNMGNYTNTGYAGYTTYYTNGGNCARGAY MGNTCNGAYGARTTYYTNCARAARGTNTGYGAYGCNACNAGYTTYCARACNATGAARCAR ACNCARGGNGTN---------------GAYATGCCNGTNTTYTAYMGNAARGGNCARGTN GGNGAYTGGCARAAYTAYTTYACNCCNGAYYTNAAYGARTGGTTYGAYGARYTNATHAAR AARGARATGGCNGGNACNAARYTNAAYTTYCARTAYAAY---YTNYTNAGYTAYGGNATH GGNCAYTTYTCNTCNTGYTCNATHGCNMGNTAYCARYTNGCNTTYYTNYTNYTNYTNMGN GARAARYTNCARACNAGYGTNTGYAGYGTNTAYGAYCCNGTNTTYACNGARCARGARACN AGYGTNYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR YTNAARCARACNCAYCARGARCARYTNAAYACNYTNACNAARCARCAYACNGCNCARATG AARAARATGACNGARGAYTTYAAYAARCARATHGCNGCNGARGARCARACNYTNAARGCN AAYYTNGARACNGARAARGCNTCNYTNCARMGNAARCAYGAYMGNGARGTNGARGARYTN AARAARGGNTTYAGYGTNMGNMGNGARGCNYTNCARGAYCARYTNGAYGAYGARGAYGAR GARATGAARGARAARAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CCNGAYCCNACNGCNGAYATGGGNAARCAYTCNTTYAGYTAYGCNYTNATGCCNCAYGCN GGNAGYYTNCARGARGCNGGNGTNATHCARCARGCNATHMGNTTYAAYAAYYTNAAYCCN GGNACNGTNATGACNGGNCARTCNGARCARGARAAYTCNAARTAYAAYCARAGYYTNTTY GARTCNYTNACNCCNCARGTNGTNYTNCARACNGTNAARATGGCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGGCNACNTCNTCNAARGCN------ACNMGNYTNAARTCNTCNAARAAY GCNATHTCNYTNCARGTNACNAARGGNGTNTCNTTYACNGGNACNGCNACNATHGCNAAR AAYTTYATHMGN------GARCAYAAYAAYGGNYTNAGYYTNGARGAYMGNATGAGYGTN GARCARTGGGTNGAYTAYAGYTGYGARATHTCNTCN------------YTNGARATHGTN GGNGARMGNGARMGNATGCARACNGCNYTNAARGAYYTNAAYGARTAYATGAARGAYAAR GTNTAYTTYGTNGGNTCNGAYYTNACNGTNGCNGAYGTNYTNATGTAYCAYAGYYTNTTY TCNGCNTTYGTNAARYTNACNATHTAYGARAARGARAARYTNATHCAYYTNTCNMGNTGG TTYAGYCAYATHCARAGYGAYAARGCNGCNMGNCARTCNYTNGTNCCNGTNAARTTYYTN MGNACNTCNYTNTAYTCNGGNATHGGNATHCAYATGAGYTCNYTNGAYACNGTNATHGCN MGNYTNAARAGYGTNGCNCCNYTNTCNYTNGCNGARAARTGGGAYAAYGTNGGNYTNYTN GTNGARCCNTCNGGNCCNAARTAYATHAGYCARYTNATGYTNACNAAYGAYYTNACNGGN GCNGTNATGGARGARGCNAARGARAARACNGTNGAYYTNATHGTNTCNTAYCAYCCNCCN ATHTTYGCNCCNYTNAARMGNYTNACNCARAARTCNTGGAARGARMGNATHYTNATHGAY TGYATGGARAAYMGNATHGCNGTNTTYTCNCCNCAYACNTCNTAYGAYGCNGTNGARGAR GGNGTNAAYGAYTGGYTNATHTCNGCNTTYGAYGTNGAYAARTCNACNATHGARCCNGTN GARGCNGCNCARAAYTAYGTNAAYGARAARTCNCARGTNYTNGARGTNGARACNYTNCCN GCNAAYTAYAGYGARGTNTGG---AARACNYTNGTNTCNTTYYTNCCNCARAAYTCNCCN ATHMGNAARAAYAARTCNTCNTTYTCNACNTCNGTNGTNMGNAGYGAYTCNACNGARTAY TGGMGNYTNMGNGTNYTNTGYAGYCARCCNGARYTNACNGAYYTNYTNAARGGNGTNACN TCNTGYCCNGAYGTNGARAARTAYTCNGTNTCNAGYYTNTCNCARGTNCCNMGNGCNAAR TGYGGNATGGGNMGNAARGCNACNYTNAAYAAYGCNATHAGYYTNGAYAARGCNGTNGCN CAYGTNAARGCNCAYYTNAGYYTNGGNCAYGTNAGYYTNGCNMGNACNGAYGAYMGNGAY GAYTAYTCNATHAAYACNGTNGCNGTNTGYGCNGGNTCNGGNTCNAGYGTNYTNAARGAY GTNAAYGCNGAYYTNYTNYTNACNGGNGARATGTCNCAYCAYCARGTNYTNGAYGCNGTN CAYGCNGGNAGYAAYGTNATHYTNTGYCAYCAYAGYAAYTCNGARMGNGGNTTYYTNAAR GARYTNCARTCNMGNYTNAGYAARGTNATGGARAARTCNGTNAAYGTNTTYGTNTCNGAR AGYGAYMGNGAYCCNYTNGARATHGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CCNGCNCARYTNGARGCNCCNCCNGTNYTNCAYMGNATHACNAAYGTNCARGAY TTYAAYCCNGGNTTYAARAARTTYTGGAARAARYTNTTYYTNTCNGARGCNTCNTCNGCN GTNYTNCARGAYGGNTTYTGGTGGATHTTYYTNGAYAARTTYAAYAARACNGAYGGNTTY GAYAARGAYAARGAYTCNYTNTTYGAYMGNATHGCNGAYAGYTTYGTNGCNYTNTTYACN AGYATHAAYACNGAYGTNAARGAYAARTTYYTNTCNGTNTAYCCNAGYTGYYTNTCNCAR GCNYTNTAYTAYACNTTYTGYGARGCNTTYCCNGARTCNAARTGGMGNTTYGAYGAYAGY TTYAARCARTAYYTNGTNAAYYTNGTNTAYGARTGGGTNACNGGNYTNMGNCCNGTNCCN GGNGTNTGGAARGCNTGGAAYGARGARGGNYTNGARGGNAAYCARACNAAYMGNGARAAY GARACNACNAARAARATGYTNGARGCNGCNGCNYTNAAYAARAARGTNGAYYTNAGYYTN GAYATGGAYGGNTTYGCNAARGTNATHGAYAARYTNGGNACNGARCCNGAYGCNACNCCN CARGGNAAYATGTCNMGNGARATHACNAARACNACNAAYAARATGTCNYTN------YTN TCNMGNGGNAARCCNCCNATHTCNAARCARGARTCNCAYCARATHGGNCCNGGNCCNGAY TAYGARMGNGTNAARTTYAAYACNTCNGGNMGNAGYCCNYTNATHGCNCAYTAYYTNCAY ATGMGNCARYTNMGNAGYTAYAARCARCCNGGNATGAARGTNMGNMGNACNGARATHYTN AARYTNCCNCCNGAYGGNCCNACNTAYCARCARTTYATHTCNAAYACNATGAGYAARGCN GARTCNYTNGARMGNGARTAYACNMGNATHTGYGARCARACNTCNAAYGCNATHYTNGAR YTNGARMGNTAYAARMGNGAYTCNAAYMGNGARATHTCNGAYYTNAARAARGCNYTNAAY GAYGTNAARAGYYTNCCNGARMGNMGNYTNYTNYTNGAYAARATHTCNGARTAYAARGAY YTNATHATHAARGARMGNCCNYTNYTNGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GCNGTNACNACN YTNTCNCCNCAYAGYYTNCCNGAYTTYTTYGGNCCNYTNGCNCARTTYGGNAARTAYATG GGNACNCARTAYTTYAAYGCNTGYATHGCNACNTGYYTNTTYACNYTNATHGCNCAYTGY ATHGARGCNGCNTAYGCNGGNAARATHTGYCARGAYMGNCAYTAYTCNGTNGARGCNACN ATGAARTGGGTNTTYTCNACNTTYGTNTTYGGNTTYCCNTCNYTNCARMGNYTNACNCCN CAYAARCCNMGNTCNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNCARMGNGARGTNACNCARGGNGAYYTNAGYAARCCNACNAARAARAGYATGGTN AGYAGYCARYTNAGYGCNACNTAYMGNGGNGCNGTNMGNGCNYTNCARATGTTYGTNAAY CARYTNCCNTAYCARGAYGTNCARATGGGNYTNCCNTCNTCNTAYAAYGARYTNGCNYTN YTNYTNMGNCARYTNACNACNYTNGCNACNYTNACNCARCARGGNTCNAARGTNGAYGGN CARGAYAGYGTNYTNGCNYTNYTNGAYCARGTNGAYGAYTTYAAYTCNAARTGGTGYACN ATGGCNYTNMGNCARGAYMGNAGYYTNAARAAYTCNCAYTCNCARMGNGGNTCNGGNAAR ACNTGGGAYAGYGAYACNAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARATHATHGCNGGNGARATHTTYACNCCNCCNCAYGAYCARYTNYTNYTNTCNGTN ATHCCNACNYTNGTNTAYAAYTCNGTNTCNTCNYTNGARGARATHTCNCCNATHYTNAAY ATHYTNACNTCNACNYTNAARATG---------ACNCARCARCARATHGTNGAYCAYYTN AAYGCNGAYGGNTTYTCNTCNYTNCAYYTNTCNGCNATGAGYGGNGAYMGNGARAGYGCN MGNYTNATHYTNGCNYTNGGNGCNGAYTGYMGNMGNCARTCNAGYAGYGGNAAYACNGCN YTNTCNYTNGCNGTNGCNTTYAAYCAYGAYTTYYTNGTNCCNYTNTTYATHCAYACNTCN GAYGTNAAYAAYGARGAYAAYGAYTCNGAYACNCCNYTNATGTTYGCNGCNTGGAAYAAY CARCCNCARATHYTNTCNTCNYTNATHGARCAYGGNGCNGAYGTNAAYTTYGTNAGYCAR CAYGGNAGYACNGCNYTNTGGAAYGCNGTNTAYCARTCNTCNCCNGARTGYGTNYTNATH YTNYTNAGYCAYAAYGCNMGNACNGAYGTNGTNTGYGARGGNACNCAYYTNTTYAARAAY ------AAYAAYAAYAAYGARGAYGARMGNGTNACNAARATHTAYCCNGGNCARTAYCCN ACNYTNYTNTGGGTNGCNGTNGARMGNGTNGGNAAYAAYCAY------YTNAARGTNYTN YTNATHYTNYTNGARGCNGGNTAYAAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARGGNTGYGTNGGNAARGTNATGGAYGTNTTYTTYYTNYTNGAYTCNTCNTCNTCN ATHTAYATHAAYGAYTAYATGTCNCARCAYMGNYTNGTNMGNGAYATHATHAAYMGNTTY GAYGTNAGYCCNGARTCNACNMGNGTNGGNATGYTNACNTTYAGYGAYGAYYTNGARMGN CCNGTNATGGGNYTNAAYMGNTAYCCNAAYMGNGAYGAYYTNGTNCARGCNATHTCNATG CARAAYYTNCCNTAYMGNACNGGNATGACNAAYACNCAYYTNGCNATHAGYTAYGCNMGN CARGAYAAYGAYTTYMGNCCNGAYATHACNAARGTNYTNATHGTNTTYACNGAYGGNGGN TCNMGNTCNCCNGGNGCNACNTCNMGNGARGCNGARYTNGCNMGNAAYGCNGGNTTYTAY YTNTTYGTNGTNGGNATHGGNCARTAYATHGARGARMGNGARTGGMGNGCNATHGCNAGY GAYCCNGAYGAYCARTTYGTNTAYAAYATHACNAAYGCNMGNTTYATGGARGAYGTNAAR TTYTCNYTNCCNCCNMGNGCNTGYGCNYTNCCNCCNATHATHTTYGGNGGNTCNTGYAAY GTNAAYCARCCNTCNGARGTNTAYTTYGTNTCNTCNMGNAGYGCNAGYCARGARGCNATH GAYTCNATHGAYTAYTTYAARAGYMGNACNMGNTCNCARMGNAAYGGNYTNMGNGTNAGY TAYYTNATHGARGCNTGYGGNTCNGTNACNAAYGTNGCNATHGAYGAYCARGAYGTNGCN ---TGYGARMGNTTYGCNCCNAGYTCNGGNGAYACNCARGARTCNGTNTCNGCNYTNATG GAYAGYGCNMGNAGYYTNTCN---MGNGAYTCNMGNAAYGAYGGNGCNAAYCARGTNATH GTNATHTTYGCNGAYGAYGCNTCNATGGCNYTNTCNMGNTTYGAYCARGTNAAYGGNGCN AARAAYGCN------------GGNGTNACNATHGTNGTNGTNGAYGCNGGNYTNMGNACN TAYAARAAYTTYGCNMGNGAYYTNGCN--------------------------------- ------------------------------------------------------------ ------------------------------------------CARGGNGGN--------- ---------GARGAYTTYGARAARGTNGAYGCNCCNGGNGGNGGNTTYGGNCAYGARGTN ACNGCNTCNTCNGGNGCNTAY------------GAYATGAAYCARGAYGAYGARATHTCN ACNACNACNGAYGCN------GCNGGNGARGAYGARGCNGARGCNGAYMGNTTY------ ------------GCNGTNGGNTCNTTYGARGAYAAYCCNGARCCNYTNATHTCNTGGGGN GAYGAR------------------------------------------------------ GAYGTNCARCCNTCNGCNCCNGTNCCNGAYAAYAAYCARCCNYTNYTNAGYTTYGAYGAY ---GAYAGYCCN---TCNMGNGAYGAY---TTYATGCARTCNTAYAARTCNTCNGTNCCN CCNCCNAGYACNACNCCNGARCCNAARTAYCCNCCNTCNCAYACNYTNCCNACNCARYTN GAYGCNTTYMGNCARCCN---------GARCARGARCCNATHGARAGYTTYMGNMGNCAR GTNTCNGAYCARAAYCARACNTCNATGGAYGCNGCNGARGGNTCNTGGYTNAARGGNGTN GAYCCNMGN---------------------------------GTNATHGAYYTNATHTAY TGGMGNGAYGTNAARACNACNGGNYTNGTNTTYGGNTCNATGYTNGTNGTNYTNYTNTCN YTNGCNATHTTYTCNYTNYTNAGYGTNGTNGCNTAYYTNTCNYTNGCNGTNYTNACNGTN ACNTTYAGYTTYACNGTNTAYAARAARATHATGGGNGCNGTNCARAARTCNAAYGAYGAY CAYCCNTTYAARGCNYTNATHAGYATGGAYATHTGYYTNAGYGARGARAARYTNAARAGY GTNATHCARAGYATHYTNAARAAYGCNAAYTGYACNATHTGYGARYTNMGNMGNYTNTTY YTNATHGARGAYATGGTNGAYTCNATHAARTTYGGNYTNYTNYTNTGGGTNYTNACNTAY TTYGGNGCNTGGTTYAAYGGNATGACNYTNATHATHYTNGCNGTNATHTGYYTNTTYACN YTNCCNAARGTNTAYGARACNTAYAARGTNCARATHGAYAAYTAYATHGGNATHGCNAAR GGNCAYATHGAYAAYGTNYTNAAYATHGTNCARAGYAARGTNCCNTTYYTNAARAARAAR GARAARGCNCAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GARATHCCNTTYGTNGCNGGNAARTCN ACNACNCCNAGYCAYTCNYTNGGNGCNAAYGTNCARAARGTNYTNGCNATGATGAARTCN CAYAAYGCNGCNYTNTGYTCNCARACNGCN---CAYGGNGGNAGYGARGGNCARMGNTCN ACNAGYCCNGGNTCNTCN---TCNGGNTCNAGYACNCCNTCNTCNGTNGGNCARGAYYTN ACNGARYTNYTNAAYCARYTNCARGARGARTTYMGNCARYTNACNAGYGARCAYCARGAY YTNGTNCARCARYTNAGYGTNGCNAGYGAYAARGCNGARMGNYTNGAYYTNGARCARGAR ATHGARGTNGTNGTNTCNMGNATGGARGCNAARGCNCARCARATHGGNAARATHMGNCAR CAYCAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MGNCCNACNTCNCARAGYYTNGCNGCNGAY---TCNATGGGNMGNACNCCNGGN CCNCAYAARCCNACNCCNGGNGTNGGNGAYAARTCNGGNMGNYTNTCNGCNTAYGAYTTY CCNGAYGAYAGYCCNGAYGARGAYCCNGTNAAYTAYATGGCNYTN---GCNGGNMGNTCN GGNMGNAARTGYCCNGTNGAYAGYTCNGARAGYAARAGYGCNAGYTGGCCNGGNTCNGAY ACNCARGCNGCNAAYAGYAGYYTNGAYGARAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ACNATHGARTCNAARCCNTCN---ACNACNCAYAAYTGYACNATHTAYMGNACNAGYGTN GTNTTYAAYGCNTCNGTNCARACNGTNGAYGAYACNTTYCCNYTNTCNCCNYTNAAYGCN TAYAARGAYTGGTCNCCNGAYATHTCNGAYGTNTGYYTNYTNGARACNCARCCNGGNGAY ATGYTNGTNTAYCARGTNAARACNCARAGYATHGCNAARATHATHTCNCCNMGNAGYTTY ATHGCNGCNGGNAARGGNGARCARCARGGNGAYAGYATHYTNMGNTAYGCNGTNAGYGTN GAYTAYACNAARCCNGTNGAYGARAGYGGNATGGTNMGNGGNYTNTAYGGNCCNTTYGGN YTNMGNATHTCNCCNAAYCCNGGNAAYCCNAARCARACNAARGTNGTNGCNATHYTNCAR ATHGAYTTYCARGGNAARGTNCCNMGNAARYTNGTNGAYTCNAGYYTNCCNTCNTCNATH ATGACNTCNATHGAYTGYTAYATHAARTAYYTNAARAAYAARGGNYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGN---AARGARGARGARGARAARGCNGAYAAYGCNGCNYTNGARGTNGTNGTNACNAAR YTNGTNGARTCNGGNCARGAYTGGGTNGCNGARGCNACNAARGCNCARGTNGAYGTNGCN AARGCNACNTGYAAYCAYAGYCARYTNYTNAARAARGCNATGGAYGAYACNTCNGAYGTN YTNCAYAARGAYGCNGARTGGGARGCNGTNACNGTNGCNTTYAARGARMGNGARATHGCN ACNAAYMGNGCNAAYGARYTNGTNGGNCARGCNAARAARAGYATHGAYAARYTNAARACN GTNGTNGARGARGGNAARGCNAAYAARGTNACNGCNAARAAYCCNGCNYTNAAYCCNGCN ACNAARAARATGGCNGARYTNTCNAARGAYYTNGCNAARGCNGCNGCNCARGTNMGNCAR GCNGAYGCNGAYGCNAARGTNATGYTNAARTAYAARGAYYTNGTNGAYAARGGNMGNMGN CARTTYCARYTNGARYTNGARAGYYTNGTNCCNGAYGTNAARTCNAGYGGNAARGGNMGN AARYTNTCNGARGARGARYTNAAYGCNYTNATHGCNCAYGCNCAYMGNMGNATHGARCAR YTNCARAARCARATHGCNGARCARGTNGCNATGGARMGNCARMGNYTNTCNGCNGCNYTN GAYACNCARMGNCARGARGAYAARCARGTNACNGARATGGCNGTNYTNGAYGARMGNACN MGNATGYTNAAYGARTTYGARYTNGARAARGARAARYTNGAYGTNGARTAYGCNGTNCAR ATGGARTCNGAYGTNMGNAARCARYTNAGYMGNCARGCNGCNGCNCAYAGYGAYCAYYTN AARGAYGTNYTNGCNGTNCARGARGARGARATGAGYMGNGAYTTYGARMGNAARATGAAY ATHAARYTNYTNGARGARMGNGARAARTTYCARTCNGARACNGGNGGNTGGATHTCNMGN YTNAARGGNATHGARGCNGCNGTNGAYGCNMGNGCNGCNAGYGARAARYTNGCNMGNMGN GCNCARGAYYTNTGGYTNGCNTGYATHGCNYTNAAYTCNACNATHATGTTYGGNAAYGAR GARGCNTCNCARTCNCCNATGCCNYTNAARACNCARGTNGARGCNGTNGTNAAYTCNGCN AAYAARCAYCCNTTYGTNGARACNATHGTNAAYAGYATHCCNGAYGARGCNYTNAGYMGN GGNGTNTAYACNGARAAYGAYATHMGNGAYMGNTTYACNAARGTNTCNCARGTNAGYCAR MGNYTNGGNYTNATHCARGARCCNAAYGCNTCNYTNTAYCARTAYYTNGTNTCNTAYYTN CAYTCNTTYTTYTCNGTNMGNAAYGTNTAYGCNGCNTCNGARTCNGAYYTNGTNTGYYTN GARGAYATGGAYAAYTTYGARYTNGTNGCNCAYGCNAARCAYTGGATGGARAARGGNCAR YTNGARATGGCNGTNMGNTTYATGGCNCARYTNCARGGNGARTCNAARGTNGCNGCNGAR GAYTGGGTNMGNGARGCNMGNYTNYTNYTNGARACNMGNCARGCNGCNCARGCNATHACN TCNTTYGCNTCNGCNACNGGNYTNGCNACNACNTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TAY GGNGARCAYTCNTAYYTNCAYYTNGARGARGTNMGNATHCAYTAYGTNATHAGYGGNCCN CCNGARAARCCNYTNATGYTNTTYYTNCAYGGNTTYCCNGARTCNTGGTAYTCNTGGMGN TTYCARATHAARGARTTYTCNAARGAYTAYMGNGTNGCNGCNATHGAYYTNMGNGGNTAY GGNGAYTCNAGYAARCCNTTYGGNGTNAARAARTAYAARYTNGARTGYATGGTNAARGAY GTNAARCARATHATHACNGCNYTNGGNTAYAGYTCNTGYACNYTNGTNGGNCAYGAYTGG GGNGGNGCNATHACNTGGGCNTTYTCNGGNTGYTAYCCNGAYATGGTNGAYAARGTNGTN ATHYTNAAYTGYCCNCCNGCNAAYGTNTTYMGNAARTAYYTNCARAGYCAYTGGGCNCAR TTYAARAARAGYTGGTAYATGTTYTTYTTYYTNGTNCCNGTNYTNCCNGARATHTAYATG GGNYTNGAYGAYYTNAARCCNYTNGAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGYTNAAYAARATHGCNCCNYTN TTYMGNGCNYTNCCNMGNGTNAARAAYGCNMGNTGYATGAGYGGNGGNCAYGGNGTNCCN GCNCAYTGGAARCCNATHMGNCARATHTGYGARGARAAYAARAGYCAYATGAAYTTYATG CCNGTNCCNCARGGNTCNTGGCARGARGCNTAYAAYGCNAARAAYTCNMGNYTNAAYATG YTNYTNYTNGGNAGYGCNGCNAGYGTNGTNGCNACNTTYGCNATGYTNTAYTCNACNGGN TGYATHTAYTTYCAYGGNCCNCCNCCN------------------------------GTN AARYTNCCNTCNAARYTNACNMGNYTNGTNTCNGARAAYCAYGCNYTNYTNGARAARTGY CARGCNGCNMGNTTYGTNMGNAARGTNCCNGAYTCNGAYGCNGCNCARACNTTYGTNAAY MGNYTN---GTNGCNCARAAYGARGTNAGYGARGARATGTGGGCNMGNGTNAARGCNMGN GCNTGYYTNCARAGYCAYAGYYTNGTNYTNGCNTCNYTNGARTCNYTNCAYATHGAYAGY ATHTCNGCNTCNACNCCNTTYGARGAYGTNTAYMGNGCNAARMGNYTNYTNGARTTYAAY YTNTCNAARTTYGCNAAYTCNCARGARGARGCNGAYTAYTTYTCNMGNGTNCARTTYAAR CARYTNCCNCARGCNCARACNCCNGARYTNCARAGYATHAGYGAYCARACNAAYCCNYTN TTYTCNGGNTGYGGNAARGARMGNAAYCARTCNCAYGAYGCNACNGAYMGNYTNYTNACN GARGCNYTNAGYMGNTCNTCNYTNTGGYTNCARYTNACNTTYGARAARCARYTNTAYCAR YTNCAYCARGCNGTNATGTCNYTNACNGARAARGARTGGTGGTCNGTNYTNGARCARAAY CCNGARGAYAGYAGYGTNTTYCARGCNGTNCAYGCNYTNYTNACNTCNAGYGGNGARATG YTNCCNTCNATHATGYTNAAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AGYCARAAYGGNYTN YTNTCNCCNGTNGGNTCNGTNGTNGAYYTNAARGGNTCNMGNYTNTCNYTNAGYCARTTY TCNGGNAARMGNTCNATHATGAGYMGNGAYAGYATGMGNGARMGNGARAARYTNAAYGCN GARGTNAAYACNATHTAYGCNGAYYTNAAYGCNMGNTAYTCNGAYATGGTNAARCAYYTN ATGAARATHGAYAARGGNYTNAAYACNAARGGNTCNTCNGCNGARTCNAGY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNGARGARYTNAAYYTNTAYATHCARGGN CAYTCNGAYACNYTNYTNGTNYTNYTNATGGARAARGARGTNGAYTGYCAYMGNMGNTTY ATHTAYTCNYTNTGGAARTCNTGYYTNTCNCAYYTNGCNGARYTNGAYTTYGARGTNAAR AAYGTNGARMGNCAYATHAARGAYGARACNGAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNATHMGNCAYGTNAARGARGARTGYGGNCARGTNGTNGAYATG ATHACNGARYTNGCNATHTTYGARAARATGGARGAYCARGTNAARACNACNGCNGAYGGN YTNMGNCARGAYATHTTYGGNCARCCNGCNMGNTGYTAYTGYYTNGTNGCNGARTAYAAY TCNGAYAARGARTCNMGNYTNYTNGGNTAYGGNYTNTAYTAYGTNGCNTAYGCNGTNTGG GAYMGNAGYTAYYTNCAYYTNGARGAYYTNTAYGTNAARCCNGAYTTYMGNCARAARGGN ATHGGNAARAARYTNTAYCARGCNGCNGCNCARATHGCNYTNGAYCARGGNTTYCCNAAR GTNGARYTNGARGTNYTNGAYTGGAAYAARCCNGCNAARGAYTTYTAYGARAARGTNGGN AAYACNGAYATGACNCARGCNGARGGNTGGMGNAARATGMGNATGCCNMGNGAYCARATG GARAARTTYGTNMGNTCNAGYTCNTCNTCNTTYYTNTCNMGNAAYMGNGAYCCNGAYTCN CCNMGNGCNGCNGGNAAYGGNAGYTTYAARTCNTCNYTNAGYGCNGTNAAYGCNGAYCCN GAYTCNCCNMGNYTNGCNGGNTGYGCNMGNCCNYTNGGNTTYTCNGTNTTYAARGAYAGY TCNTCNTCNGTNGGNTAYYTNTCNMGNTTYMGNGAYGGNGAYMGNYTNGGNGGNAARGGN GTNGARTCNGCNCAYTCNMGNGTNTCNGGNCAYCARTCNCCNMGNCCNTTYACNTCNTCN GTNGCNGCNTCNCCNTCNTCNGCNYTNGCNCARCARCARACNGAYAGYATHGCNCARYTN GARAARCARYTNGARAARGARMGNGARGAYAAYMGNMGNYTNAARCARGARATGGARGAR AARGAYAARAARATHGCNGARYTNGARAARTCNGTNGARYTNYTNAAYAGYGARTGYGAY GGNYTNGAYGARGAYAAYYTNAARYTNCARGARGARAAYAARGCNYTNATHMGNGCNATG GCNAARYTNAAYGCNAAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GCNAARCARAARGCNATHACNMGNCCNGCN TCNTCNTTYACNAAYCCNGARATHMGNGTNTCNAARTCNMGNGCNYTNGTNGAYGARAAR GTNTGYATHACNGCNACNGGNYTNYTNMGNGGNCARAARGTNACNYTNCARACNTTYGTN AARGAYGGNGAYAAYGTNTTYGGNGCNTGYGGNCAYTAYATHGCNAAYAAYGAYGGNAAR GTNGAYACNTTYMGNGAYGARTGYCARGGNGGNACNTAYGAYGGNATHGARCCNATGGGN YTNTTYTGGAGYATGCARTCNTCNCCNGGNAGYAARCCNMGNMGNATHATHAAYTCNGAY GTNACNAGYCCNTTYAARGTNMGNATHGCNYTNCAYGAYGAYTTYAARAGYTTYGARGAY YTNCCNTGGAAYGARGGNTTYCCNTCNYTNGCNTCNTGYATHTTYCAYCARATGTAYAAR GCNCCNGGNGTNMGNGTNATHCCNGTNAARGARGAYGGNYTNYTNGGNACNYTNTGYYTN CCNCCNGGNGARGGNCCNTTYCCNGCNGTNATHGAYATHTTYGGNATGACNCAYYTNTAY CCNTCNCAYMGNTCNGCNYTNYTNGCNTCNAAYGGNATHGCNTCNTTYGTNATHGCNTAY GTNGCNAAYGARGGNYTNCCNGAYTCNGCNGCNACNYTNGAYTTYTCNTAYTTYYTNAAR GCNTGGGAYTGGYTNTCNMGNCAYCCNAGYATHAAYCCNGAYGCNATGGGNGGNATHACN AGYTGYATHGGNGGNGGNTAYGGNACNATHATHGCNTGGAARMGNCCNTCNATGAARTGY YTNGTNGGNYTNAAYACNTGYGTNTAYCCNAGYGGNCCNMGNCARATGATHGARGGNGAY YTNTTYGARACNYTNGAYTGGMGNYTNCAYMGNGCNAARGTNYTNGAYGAYGGNATHTCN TTYMGNCCNYTNTGYACNGTNGARGAYAAYGCNCARGCNYTNCCNTAYTGGMGNCAYGGN ATHAARGTNYTNTAYGTNCARGGNYTNGAYGAYYTNAGYGTNGAYCCNGAYGTNYTNTAY TAYGGNCAYGCNGCNATGCCNGARAAYATGAARGAYAAYATHCARTTYATHMGNTAYCCN GGNGCNGGNCAYATHATHGARCCNCCNTAYATGCCNYTNTGYMGNTCNAAYTAYATGAAR ATHTTYAARCARGTNCAYYTNTGGGGNGGNCARCCNAARCCNCAYGCNCAYGCNCARATG GAYAGYTGGCCNMGNGTNGTNGCNTTYYTNAARGARCAYYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATGCAYCCNTAYTAYTAYGTNCARTAYGTNCCNATHCCNYTNAARCARGAYYTNGAR ATGAARGTNAAYTGGGCNGCNTCNCCNAAYACNGCNCCNAARCARGAYACNAGYAARCAY CAYCAYGTNTTYGTNGGNGAYYTNAGYTCNGAYATHGARCARCAYCARYTNMGNGAYGCN TTYGCNCCNTAYGGNGARATHTCNGAYTGYAARATHATHMGNGAYCCNACNACNATGAAR TCNAARGGNTAYGGNTTYGTNTCNTTYATHAAYAARCAYGARGCNGARAAYGCNATHGGN GGNATGAAYAAYCARTGGYTNGGNGCNMGNCCNATHMGNACNAAYTGGGCNGCNMGNAAR CCNYTNGCNCCNCCNGCNAARGARAAYTCNAARCCNYTNGCNTAYGAYGAYGTNTTYAGY CARTCNAGYTCNACNAAYTGYACNGTNTAYTGYGGNGGNGTNTCNAAYGGNYTNTCNGAR GARYTNATGMGNAARACNTTYACNCARTAYGGNACNATHCARGARGTNMGNGTNTTYAAR GAYAARGGNTAYGCNTTYATHMGNTTYAGYTCNAARGARTCNGCNACNCARGCNATHTGY GGNGTNCAYGGNACNACNGTNAAYGARCARCARGTNAARTGYTCNTGGGGNAARGARTCN AAYGARTCNACNCARAGYAGYCARCARTCNAGYAGYCCNCCNGTNGTNATGYTNCCNTCN CARCCNCARCARCCNYTNACNGCNCCNGCNGCNGCNACNCARTAYGGN---CARTTYTAY AAYATGAAYTAYTAYCAYGGNGCNCCNTAYGCNGCNGGNACNCCNACNTAYCARAGYGCN GTNCCNGCNCARGGNCARTTYATHCCNACNGCN---GGNCARTGGCCN---GGNTAYTCN AAYTAYCARGCNTAYGGNAGYATGAAYATGCCNGTNGGNCARTAYGCNGGNYTNCARATG CARCCN---GGNGCNCARCARGCNGCNYTNGGN---GGNCARGGNATGGTNGGNTAYCCN ATGCARCAR---ATGGCNAGYTCNAAYATHMGNTAYGARGTNYTNCCNTCNGARGARCAR AAYGTNCCNGCNGARCARGTNGAYYTNGCNATGGTNGTNCCNCCNCCNAGYTAYACNGAR ACNCCNGTNATGGARCARCARGAYAAYGARCCNGCNTTYGGNCCNGCNAARYTNCCNAAY TAYGTNGARGCNACNACNYTNCCNTCNTAYGARGARGCNGARMGNATHAARYTNGARCAR GAYGARAAYAAYCCNATH------ACNGAYYTNGARGCNGGNMGNYTNACNACNYTNGAR GGNGTNAAYGARGCNAAYATHGGNACNGAYAGYATGTTYATHTGYACNTTYTTYATHTCN TTYYTNTTYAAYTGGTTYGGNTTYYTNYTNTCNYTNTGYYTNACNAAYACNATHGCNGGN MGNTGYGGNGCNYTNTCNGGNYTNGGNYTNTCNATHGTNAARTGGGTNGTNATHGCNAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AAYGCNGAYTTY ATHCARTCNYTNATHACNGCNYTNGGNYTNACNAARCCNGTNATHGTNTCNCCNTCNATG AGYGGNTCNTTYTCNYTNCCNTTYYTNTTYGGNGAYAARGTNAARGGNGARGARMGNGCN ACNGGNTAYGTNCCNGTNGCNCCNGTNCAYACNGCNCARTTYYTNAARAAYTAYCCNAAR AGYCARYTNCCNACNYTNATHGTNACNGGNTCNAAYGAYYTNGGNYTNGGNTCNACNAGY AAYGARCAYTTYGGNAGYYTNCCNMGNGGNCARTAYGCNGTNATHCARGGNGCNMGNCAY GCNTGYTAYATGAAYGAYCCNGAYGCNTTYCAYMGNTAYYTNTAYCAYTTYYTNTCNGAR YTNTTYATHTTYYTNGTNATHGGNGCNATHYTNGCNAARTAYGGNTAYGAYTTYATHMGN TAYTGGMGNTTYTTYAGYAARATHCCNGGNYTNGARCCNTTYAAYYTNATHTAYGGNAAY YTNAAYYTNYTNCCNGGNCCNAAYGARAARGGNYTNGARTAYGARATGAGYYTNATGMGN AARTTYGARAARTGYTAYMGNATHTGGGCNGGNCCNTTYGTNCCNGTNATHGTNTGYTAY CAYCCNGARGTNGTNAARACNYTNYTNAARTCNTCNGCNCCNAARCCNMGNGGNACNATH TTYMGNACNCCNTAYGAYATGGGNYTNGARTGGATHGGNGARGGNYTNYTNYTNTCNAAY GGNCAYAARTGGAGYMGNAAYMGNMGNYTNYTNACNCCNGCNTTYCAYTTYGAYATHYTN AARAAYTAYYTNAAYGTNTTYAAYGARTGYGCNCARYTNTTYYTNAAYAARYTNGAYTCN AARCARGGNGARTCNTTYGAYATHTTYACNCCNACNTCNTAYTGYACNYTNGAYGTNATH YTNMGNACNGCNTTYTCNCAYCAYTCNGAYTGYCARACNTCNAGYGARCARACNTCNTAY GTNAARAAYYTNAARGARYTNGTNGCNYTNTGGACNGTNMGNTCNTAYAAYCCNACNGTN CAYAAYGARTTYATHTAYAARYTNACN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGTCN TCNGAY---GARATHGAYTAYGTNAAYMGNGAYCCNAAYAAYYTNAAYGAYCAYGTNAAR GTNTGYTTYGAYGARGTNATHGGNGARCCNGAYGGNGCNCAYTCNATHAAYTGYGTNTGG AARTGYTCNCAYTCNTGYTTYAAYTGYTGGAARAAYTGYTGYTAYAAYATHYTNACNATH YTNTGYGCNATHCCNATHGCNATGTGYTGGGGNTGYGARTTYGCNTAYATHACNTTYATG CAYGTNTGGACNGTNACNCCNTGYATGMGNGCNTAYATGATHCARTGYGGNTGYATGCAR AARTTYTAYGGNATGTGYYTNCARTGYTGYATGCARCCNTGYTTYGARGCNATGGGNTTY TGYTTYAAYAAYATHAARGTNACNAARGTNAGY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GARTGGAAYCCNAGYTCNCAYTCNYTNTCN AARMGNCAYAARAGYTGGGCNAGYGAYYTNAAYACNACNCARAAYACNTCNTTYATGACN MGNGAYAGYYTNACNGAYTTYYTNMGNYTNAGYCARTCNGTNGGNAGYCCNMGNAARGAY TTYAARGAYYTNCARACN------------AAYGTNCCNGAYACNAARGARYTNTGYMGN MGNYTNGARGAYAARATHAAYAGYYTNACNMGNATGGGNGGNAAYYTNCARAARGARAAY MGNGARATGGCNAGYYTNATHGARMGNCARGGNGARAARYTNGAYACNGTNAARCARTTY GARAGYAAR---------------ATGGCNTCNTCNAARACNCCNAAYAARYTNGCNAGY TGGAAYCARGARACNAARACNMGNYTNAAYGARAARATHACNGCNAAYATHACNGAYGTN GGNTCNYTNGCNMGNCARGTNATHMGNGGNTCNAARACNAAYGARTTYYTNGCNCARGCN GCNAARAAYTTYGCNTCNCARGARAGYTAYGTNCARAAYTCN------------ACNGAR ACNATGAARAARATGGAYATGYTNMGNTCNCARYTNCARTTYCAR--------------- ---------------------------------CAYTCNTCNATHTCNMGNAGY------ ---YTNAGYTAYGTNCARGAYCARYTNTCNACNYTNCARCAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARAAY GGNAAYAAYGARACNGAYGAYGAYGAYGAYAAYGARGAYGARAAYGAYGARGARGAYGAY GAYAARGAYGARAAYGARAARYTNAARGCNCCNACNGARYTNYTNATGGARTTYATHGAY TGYYTNGTNAARAARGAYTTYCCNAAYGCNAGYAARYTNTGYAARATGATHYTNATHTAY GARCCNGARAAYGARGARGCNYTNAARTTYCARCCNYTNATHGARGARAARATGGCNYTN GAYGCNGCNGCNGARGARGARAGYAGY--------------------------------- ------------------------------------------------------------ ---------------------------------TGYATHGTNACNGARAARGAYYTNACN ATHGTNGCNGARGGNCCNAAYYTNATHATHCAYCARGCNGAYGAYGTNYTNGAYGGNATG AAYGARTGGTGYGTNCARCAYCAYGGNGARTCNGGNYTNACNGARGCNGTNMGNAGYTCN AARATHAAYGTNGCNGARGCNGARAARATGGTNYTNGARTTYGTNGARCARCAYACNCCN AARGGNMGNTGYCARYTNGGNGGNAAYTCNGTNGGNTGYGAYAARGARTTYATHACNMGN TAYATGCCNTCNYTNGCNCARCAYYTNCAYTAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARCAYGTNGTNAAYTGYGTNCARCCNAAYCCNCAYYTNCCNGTNATHGCN TCNAGYGGNATHGAYTAYGAYATHAARATHTGGTCNCCNCARGCNGARGARTCNCARTTY GAYGTNGAYGTNGCNCAYATGATHGTNCARMGNAAYGARCARATGYTNGTNGARACNMGN GAYTAYGARGGNTAYGARYTNYTNTCNATHGAYGTNACNTCNGAYAARGAYGTNGARATH YTNCAYTCNATHGARMGNGAYTTYCAYAARYTNGAYTTYTGGCARMGNCCNGCNAAYGGN MGNACNTGYACNGTNYTNTCNCCNCCNGCNYTNYTNCCNGGNYTNAARACNTCNYTNACN GAYCAYGGNATHGCNTGGACNMGNAARGAYGTNGAYGTNGAYMGNYTNATHCARGCNGGN ATGGARMGNAAYCCNACN---ACNTCNMGNGARAARMGNTCNACNGAYAGYGAYYTNATH GAYCAYCAYAAYTAYCAYGAYTAYGAYCARATGATHGAYTAYATHAAYCARYTNCAYTCN GCNTAYCCNAGYYTNGTNAAYGTNTCNTAYYTNCCNTAYTTYACNCAYGARGGNMGNMGN ATGATHACNTTYAARYTNCAYGGNGCNCCNGGNTCNAAYCCNAARAARTCNATHYTNGTN GARGCNGGNATHCAYGCNMGNGARTGGATHTCNCCNGCNGCNACNYTNTAYTCNGTNGAR AARATNYTNCARNNNTAYNNNGCNNNNNNNCARNNNNNNMGNYTNATGYTNGAYTCNTTY GAYTGGCAYTTYGTNCCNNNNACNAAYCCNGAYGGNTAYNNNTAYACNMGNMGNNNNCCN NNNACNMGNYTNTGGMGNAARAAYMGNMGNATGCARTAYNNNNNNTGYNNNGGNGTNGAY YTNAAYMGNAAYTTYGAYNNNTAYNNNGGNACNACNGGNGTNTCNNNNNNNTGYNNNAGY AAYNNNTAYCCNGGNNNNAARNNNTTYTCNGARCCNGARNNNGTNAAYATHAARCAYYTN TTYTCNTCNYTNAAYNNNNNNYTNNNNNNNTAYYTNNNNGTNCAYTCNTAYTCNCARNNN NNNYTNGTNCCNTGGAGYNNNTCNAAYNNNNNNNNNNNNCCNNNNNNNNNNNNNNNNYTN NNNCARYTNNNNNNNGANATGNNNNNNNNNATNNNNNNNNNNNNNGGNAARNNNTAYNNN GTNGGNNNNGCNTAYGAYYTNYTNNNNTAYGCNGCNAGYGGNNNNTCNNNNGAYTGGGCN YTNNNNNNNNNNNNNGANNNNNNNTCNTAYNNNNNNGARYTNMGNCCNNNNTAYAAYGAY ACNNNNGGNTTYNNNYTNCCNCCNAAYGARATHATHCCNACNGGNCARGARYTNYTNGCN NNNNNNAARACNATGGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGNCARATGTGYTAYACNTGYCARTAYGTNYTNAAYGGNCCNGGNATH GARTGYTCNACNGCNCCNYTNAAYTGGACNGGNGGNAGYATHMGNATGAARTGYCCNAAY AARTGYACNACNATGGCNGARTTYGAYGCNACNTCNGGNAARCCNACNTTYTTYCAYMGN GGNTGYGGNGTNGCNTCNAAYGAYCARAARGAYGGNTGYGTNGAYAAYGGNGCNMGNCAY AGYTGYTTYTAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNYTNATHTAYAAYCCNATGCAR ATHGTNTTYGGNGCNTTYTCNATHGGNGCNATGCARGCNTGGYTNGARAAYCARAARMGN GTNMGNMGNAARCCNCCNTTYAGYTGGAGYTTYTCNGGNTGYGGNGTNTTYGTNATGGCN ACNGGNTTYGTNCCNATHGARAAYMGNGGNATHTCNGTNYTNYTNYTNGCNYTNGCNYTN GGNTTYGAYGGNYTNAGYTAYTCNGGNYTNTTYGTNAAYCAYGTNGAYTAYGGNCARMGN TAYGCNGGNGTNYTNTAYAGYATHGCNAGYAGYGTNGCNTCNYTNGCNGGNYTNTTYACN CCNATHGTNTCNGGNGCNYTNACNCCNAAYAARACNATHGARGARTGGMGNACNGTNTTY YTNATHTGYGGNGGNTTYGCNGTNATGGGNGCNYTNGTNTTYGGNYTNTTYTCNAARGGN GARCCNGARCCNTGGGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CCNYTNAAYAAYATHGTNGAY GTNGAYATHCCNAGYATHATGAARCAYMGNAARATHYTNAAYAARGCNATHYTNGAYATG GAYTCNGCNAARTCNMGNTTYAAYCARGCNATHMGNCARTCNAGYATGCCNGGNACNAAY ATGTCNAAYGCNGCNAAYAARGTNGAYACNATHMGNGAYGARYTNGARGARGCNGARTGY AARATGGARAGYAAYAARGAYAAYYTNGCNATHGARYTNTGYAAYTTY------------ ------------------------------------------------------------ ------GAYGCNGARAARAARAARGGNAARCCNCCNTCNAARATHGTNATHMGNMGNYTN CCNCCNTCNYTNACNCCNGARGAYTTYYTNGARCARGTNTCNCCNYTNCCNGAYCAYGAY TTYTTYTAYTTYGTNMGNGCNGAYMGNAGYYTNGGNACNAAYGCNTTYACNMGNGCNTAY ATHAAYTTYYTNAAYGCNGARGAYATHTTYATHTTYMGNGAYAARTTYGAYGGNTAYGTN TTYYTNGAYGCNAARGGNGGNGARTAYCCNGCNATHGTNGARTTYTCNCCNTTYYTNAAR GTNCCNAARAARAARCARMGNAARCCNGAYTCNAARTGYGGNATHYTNGARCARGAYAGY GAYTAYAARAARTTYYTNGARATGYTNACNAGYCARATHGARACNGARGCNGTNTCNYTN GAYGCNATHGTNGARGARGTNGARGCNAARGARYTNMGNCARGCNAARATGGCNACNAGY AARACNAGYACNCCNYTNYTNGARTTYYTNAARMGNMGNAARGARGARMGNMGNATGAAY ACNATHAARATGMGNGAYGAYMGNMGNMGNGGN---GGNMGNGARAARGAYTAYGAYMGN AARMGNMGNGARGAYATHGAYMGNAARGAYMGNGAYMGNGAYMGNGAYCAYGAYMGNGAY MGNGARMGNGTNAAYGAYCCNGARMGNGAYMGNATHMGNGARMGNGARMGNMGNAARGAR MGNTCNMGNGARAARGARMGNGARMGNMGNMGNGAYMGNGAYCCNYTNMGNGCNGGNMGN GGNAARGARMGNCARGGNGGNYTNGGNACNTCNTCNGGNAARTTYCAYGARGARMGNTCN MGNCCNGTNATGYTNYTNAAR------------------AARAARTCNGARAARGARMGN GAYGTNTCNGAYGGNGARACNGARCCNGAYGCNYTNAAYGARMGNGARMGNGAY------ ------CAYGCNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CCNGARAARATHMGNGGNGGNGGNGARYTNTTYAARTTYCCNTGGACNACNTAY TCNAARGTNCARCARTTYCCNTTYAARTTYTAYTGGACNCAYGCNMGNYTNTTYMGNTAY TTYTGYTAYTCNACNGTNYTNATHYTNCCNYTNATGGTNAARYTNACNAARGCNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNGCNGTNCCNAARATGMGNMGNACNYTNGARGGNGTNMGN GGNCAYCCNTAYACNMGNGTNTCNYTNTCNATGACNGAYACNATHCARGTNYTNAARTGY GGNGTNTGYTTYACNCCNCCNGCNYTNGTNATHACNTAYAARGAYMGNAARTCNGGNAAR ATGMGNMGNMGNTCNATGCCNYTNMGNAAYTTYTCNAARCAYTCNACNGTNGARMGNATH TGYGARGAYYTNAARACNAAYACNMGNCAYGCNAARTTYATHMGNYTNATHGCNCCNYTN CARYTNCARMGNYTNYTNACNATHGTNAARGAYAARYTNAGYGGNYTNAGYYTNGARGCN AGYGTNGCNMGNAAYAAYCARYTNGAYTCNATHGAYCCNGARGARAAYYTNAAYAARGTN GAYGARGARACNYTNCARMGNAARAARYTNGCNATGAAYTCNTCNTTYGARAARAAYCAR AARMGNYTNGGNGAYCCNGAYTTYGARTAYAAYATHGARGTNGAYTTYGARTCNGGNGCN ATHGARACNAGYGGNTGGGAYTCNGARAAYTCNGAYATGGAYTTY >leonina YTNATHATHGCNCCNYTNYTNGTNGGNGTNGCNYTNGGNGGNTAYGAYGCNTAYGGNGAY YTNGCNCARYTNTAYMGNATGCARYTNYTNGCNGARGCNTTYGGNGAYTAYAGYCCNAAY ACNYTNGGNYTNGAYCARTCNGAYGTNGAR------ATHMGNTCNCARTGGCCNGAYTTY GCNGCNAGYYTNGAYGARGCNGCNGCNGCNAARGCNCCNGTNGARGAYGARYTNTAYGGN GCNCARGCNTAYAGYGGNGCNCARATHMGNGAYCCNGARCARATHGARCAYAGYGCNYTN CAYGGNTAYCARTCNGTNTCNGGNGGNAAYCCNGARGGNCCNTCNAAYACNAARCARCAR AARACNGAYAARCCNYTNCCNGCNTAYTGYAAYCCNCCNAAYCCNTGYCCNGTNGGNAAR ACNGCNAARGAYAAYTGYGTNGARAAYTTYGARAAYTCNGCNGARAAYAAYAARAARYTN YTNTCNGARCARGAYTGYCCNTGYGAYACNGARCAYATGTTYAGYTGYCCNGCNGGNAAR GARACNGTNTCNTCNAARGGNCARTCNGGNTAYCARCARACNYTNAAYAARGTNATHGAY CARYTNAAYAARATH------------GGNTCNCARGAYGAYCARGARAAYGGNAGYCCN CCNAARACNCARATHAGYYTNGTNGCNAARAARTCNCCNCAYATHATHCAYAARMGNTCN GARTGGATGGARAGYGCNAAYCCNTAYYTNAARGGNGCNAARATGAARATHGCNGCNAAR AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHGTNTCNGGNYTNYTNCARYTNATHGCNGCNGCNTCNGTNGARGAY AARTAYGARCCNATGGTNGCNTTYATHTGYAARMGNCCNGCNATGCAYMGNGGNGTNAAY GGNTGGATHGCNGAYAARTCNCARAAYTGYCCNGAYACNYTNGARGAYGTNYTNGCNTAY TGYAARAARATHTAYCCNGAYCAYAAYATHACNAAYGTNGTNGARTCNTCNMGNYTNTAY GAYATHCCNAAYTGGCCNATGGGNGAYGCNCARMGNAGYYTNACNCAYCAYGTNMGNCCN TTYMGNTGYYTNGTNGGNGGNTTYCARTCNGAYGCNYTNYTNGTNCCNCARCAYTGYGAR TTYGAYCAYMGNCAYGAYATHACNCARTGYAARGARTTYTCNCAYTGGAAYMGNGTNGCN GARGAYGCNTGYGAYAAYAARGGNATGCAYYTNGARTCNTTYGGNATGYTNYTNTAYTGY AAYACNYTNGGNCAYTTYAAYGGNGTNGARTAYGTNTGYTGYCCNAAYCCNTCNGARACN MGNGTNCAY------CCNGARCCNGAYACNGAYGAYAARCCNGAYYTNTGGTCNAARCCN ------------------------------GTNGARGGNGGNGAYTCNTCNGCNTCNCAR GARCARMGNTCNGARCARTCNGARGARGAYAGYAGYAGYGTNCCNTCNATGCCNGAYYTN CCNCARYTNCCNCARCARCARYTNCCNCARGARGARGTNGCNGAYYTNTAYGARGCNTAY YTNMGNGGNATGCCNTTYCCNTCNCARTTYAAYAAYGARCAYAARATGTTYYTNGCNGCN AARYTNMGNATGAARCARAAYCARAARAARAARGARGCNAARYTNYTNCARGARTGGGAR AARGCNMGNGARMGNGTNAAYGARGTNMGNAARACNGAYGCNAARACNGCNGAYMGNATG AAYGARGARATHGCNGCNMGNTTYAARCAYYTNTAYAAYTCNTTYCARCARGARGAYGAY GCNGARAARCARCARYTNYTNGCNYTNCAYCARCARCAYATHCARGCNTCNYTNAAYGAR AARAARMGNGARGCNATGGAYAARTAYATGCARGCNYTNGARTCNGGNGAYGTNGARAAR ATHACNCAYTAYYTNCAYAAYTAYATHAARGCNGARGARAARGAYMGNATGCAYACNGTN AAYCAYTTYGARCAYATHMGNTAYTCNGCNCCNAARGARGCNYTNMGNATHCAYMGNCAY ATHATHAAYCAYYTNAARYTNTCNGARYTNMGNATHGAYCARGCNYTNGAYATGYTNACN CAYTAYCCNGAYATHGARGTNAARGTNMGNCCNGARATHGARGARTTYATGAARMGNTTY GAYGCNATHGCNACNAGYATHAARAAYGTNGTNYTNCCNGARCCNCARGTNGARGARGAY AGYCARGARGAYTCNGTNAGYACNGARAGYGAYGAYCARACNCCNGARATGMGNTCNCCN GTNGARGARYTNMGNACNCCNGAYGTNGTNAGYAGYGAYAGYAGYMGNMGNATHATHGAY ------------------------------------------------------------ ---------------------------GAYGARGTNGARGARGAYGARCAYAGYTTYAGY AAYAAYGTNCCNTTYTCNGCNCAYGCNCARGCNGAYACNCARAAYGCNMGNCAYGGNATH CARTCNGGNGTNCARCAYGGNAGYCARATHGGNAGYACNGTNGGNATHGCNYTNGGNAGY GTNAGYGTNTTYGTNATHATHGTNGTNGCNGTNATGATGATHCAYMGNAAYMGNAAYMGN CARACNGTNTCNCAYGGNTAYGTNGARGTNGAYCCNMGNGCNTCNCCNGARGARMGNCAY YTNGCNAAYATGCARATGAAYGGNTAYGARAAYCCNACNTAYAARTAYTTYGAR------ CARAARGAYAARYTNTAYAARCARATHACNGTNGARGTNAARGGNCAYGAYYTNGARGTN ATHAAYAGYTAYCARAARTTYACNACNATGGCNGCNGARCAYYTNGGNGTNAARATHTCN AARATHTCNACNCCNCCNMGNGTNATHACNMGNCARAGYYTNYTNAARTCNGTNTTYGTN CAYAARAARCAYCARCAYCARTAYGARACNMGNACNAAYTAYMGNGARTTYGARTTYAAR CAYYTNACNGARTCNACNGCNYTNACNTTYYTNGARTAYATHCARMGNAGYYTNCCNGAR GGNYTNGCNATGAARGTNACNAARCAYGARYTNCARCCNATHCCNGARCAYYTNAARCCN CCNATGAARTCNAAR------TCNTCNACNCCNTCNGAYTAYTTYAAYGTNATGYTNGGN TCNCARYTNYTNTAYAARTTYGARMGNCCNCARTAYGGNGARGTNYTNGCNGARCAYCCN GAYAARCCNATGTCNAGYATHTAYGGNGCNACNCAYTTYYTNMGNYTNTTYGTNMGNYTN GGNGCNATGYTNGCNTAYACNTCNYTNGAYGARMGNACNGTNCAYATHYTNYTNAAYCAY GTNCAYGAYTTYYTNAARTAYATGTCNAARAAYGCNTCNACNYTNTTYAARACNTCNCAY TAYGARATHGCNACNCCNGAYTAYCAYMGNAARGCNATH--------------------- ---GARTAYCAYAARTAYTCNMGNCCNGTNGTNAAYGCNTCNCARATHGTNACNGTNAAR TTYGGNYTNACNYTNGTNCARATHTCNGAYATGGAYGARGTNAAYCARGTNYTNACNYTN AAYGTNTGGYTNGARCARGARTGGTTYGAYGARMGNYTNACNTGGGAYCCNAARGAYTAY AAYAAYYTNCAYATHYTNMGNATHCCNTGYGARAARYTNTGGYTNCCNGAYATHGTNYTN TAYAAYAGYGCNGAYGAYTTYACNGCNGGNTAYATGAAYAGYAARGCNATGGTNGARTAY AAYGGNAARGTNTTYTGGCCNCCNCCNGCNAARTTYMGNAGYTCNTGYACNATHGAYATH ACNTAYTTYCCNTTYGAYGAYCARATHTGYGARYTNAARTTYGGNTCNTGGACNTAYGAY GGNTTYCARGTNGAYATHACNAAYMGNTCNGCNACNGTNGAYYTNCARAAYTAYGTNYTN AGYGGNGARTGGGARYTNATHAARGTNGGNYTNAARMGNACNGARGTNACNTAYGCNTGY TGYAARGARCCNTAYCCNGAYGTNMGNTTYACNATHGTNATHMGNMGNAARACNYTNTTY TAYYTNTTYAAYATHATHTTYCCNTGYYTNTGGYTNACNATHYTNAGYYTNYTNGGNTTY TGGYTNCCNCCNGAYTCNGGNGARAARATHACNYTNGGNATHACNGTNYTNYTNGCNTTY TCNGTNTTYATGYTNYTNATHGCNGARAGYATGCCNGCNACNTCNGARTTYGTNCCNYTN ATHGGNATHTAYYTNACNGTNACNATGGGNATGACNTCNYTNTCNATHATHYTNACNGTN TTYGTNYTNCARYTNCAYCAYGTNGGNCCNCAYCARAARCCNGTNCCNAARTGGYTNMGN ACNYTNGTNTTYCAYTTYYTNGCNMGNYTNGTNTGYATGTGY------------GGNACN AARTGYATHMGNAAYGTNAARAAYTAYAAYTGYTGYCCNGARCCNTTYATGGAYGTNACN TTYTAYATHYTNATHMGNMGNMGNGTNYTNTAYTAYTTYYTNAAYGTNATHATHCCNTGY ATGYTNYTNTCNACNYTNTCNYTNACNGGNTTYYTNYTNCCNCCNGAYTCNGGNGARAAR GTNACNYTNGGNYTNACNGTNYTNYTNGCNTTYTCNGTNTTYATGYTNYTNGTNGCNGAR AAYATGCCNCCNACNTCN---------------AGYAARCARMGNTGGATHCCNYTNGAR TCNAAYCCNGTNGTNGTNAAYAARTAYGTNTAYGGNYTNGGNATGGAYAARGCNTGGAGY TTYGTNGAYGTNTAYGGNYTNGAYCCNGARYTNYTNGCNATGGTNCCNAARCCNGTNGGN GCNGTNGTNYTNYTNTTYCCNGAYTCNTCNTCNCARACNGCNACNGARAAYCCNYTNGGN GARGTNATGAARGAYATHCCNGGNGARATGTAYTAYATGAARCARACNATHGGNAAYGCN TGYGGNACNGTNGCNATHGTNCAYGCNYTNGCNAAYAAYAARGAYAARATHCARTTYGAY GARTCNAARCAYTTYTCNAAYTTYYTNACNGCNAGYGCNGCNATGAGYCCNGAYGARMGN GCNGAYCAYYTNGARAARGAYYTNGCNATGGGNGCNGCNCAYGARGAYTGYGCNCARGAR GGNGAYACNGCNGCNCCNGCNGCNTCNGARAARGTNAARTGYCAYTTYATHGCNYTNGTN AAYGTNAAYGGNACNYTNYTNGARYTNGAYGGNMGNAARGARGGNCCNGTNAGYCAYGGN GCNACNACNGARGAYAGYYTNYTNGARGAYGCNGCNGCNGTNGTNAARAARTTYATGGAR MGNAGYCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYTAY TTYMGNCARGCNYTNCARGARTTYTCNGAYGAYAAYGTNCARTAYYTNGARYTNMGNGGN GTNTTYTCNGGNYTNTAYGAYYTNGARGGNAAYACNTAYGGNCCNGARMGNGTNYTNGAY YTNTAYMGNAAYGTNACNGARGARTTYGTNAARGGNAAYCCNGGNTTYTCNGGNGCNAAR TTYATHATHACNTCNATHMGNAAYCARCCNACNAARAAYATHGARAGYYTNATGAARATH AGYATGCARYTNCAYAARAARTAYCCNGAYTCNATGGTNGGNTAYGAYYTNGTNGGNCAR GARGAYCCNAAYCAYCCNYTNYTNTTYTAYYTNAARGARYTNYTNATGCCNTCNCARCAR GAYTCNTCNGGNAARYTNCCNTTYTTYTTYCAYGCNGCNGARACNGAYTGGCARGGNACN GCNACNGAYGAYAAYYTNGTNGAYGCNATHYTNYTNAAYACNACNMGNATHGGNCAYGGN TAYGGNYTNGTNAARCAYCCNAARYTNGTNTCNYTNGTNMGNGARAARGGNATHGCNGTN GARGTNAAYCCNATHTCNAAYCARYTNYTNGGNYTNGTNAARGAYYTNMGNAAYCAYGCN ATGGTNCCNYTNATGATGGAYGAYTTYCCNGTNGTNGTNAGYTCNGAYGAYCCNGCNAAY TGGGARGCNYTNCCNYTNTCNCAYGAYTTYTTYATGGCNTTYATGAAYATGTGYGGNGAR GARACNGAYYTNMGNTTYYTNAARCARYTNGCNATHAAYTCNATHAARTAYAGYGCNATG AAYGAYAGYGARAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATGGCNGAYYTNATHCAYAARYTNTTYGGNCCNAAR CAYGGNAARGGNGGNAGYCCNGGNMGNACNACNGTNGARCCNGARGGNTAYACNAARCAY CARCAYGARTTY------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CCNATHCAYTGYTGG GTNCCNGTNCARTTYAARAARAARCAYTTYCARAARTAYTCNGAYAGYTAYTGYTGGGTN CAYCCNATGTAYAAYGTNCCNTTYGARGARGARATHCCNTTYAAYTCNGARGAYMGNTGG TAYAAYGAYGTNAGYTTYTAYMGNTGGGTNTTYYTNGTNTTYYTNTTYCARGCNTTYYTN TTYAARYTNCCNAAYATHTGYTGGAARGARATGAARAAYTAYTCNGGNYTNAAYGTNGCN AARATHGTNGGNATGGCNYTNGAYACNTCNATGYTNACNCARGARGARMGNGARAARAAR ATGAAYCAYATHGCNATHTTYATHGAYMGNTGGYTNAARACNTAYTCNCARTAYMGNTTY AGYGCNATHACNMGNTTYMGNGAYAARTTYTCNAGYATHATHTTYTGYTTYGGNAARMGN ACNGGNAGYTTYYTNAGYGGNYTNTAYATGTTYACNAARATHYTNTAYTTYATHAAYGTN GTNGGNCARTTYTTYYTNYTNTCNGCNTTYYTNGAYGTNAAYTTYTGGTCNTTYGGNTTY GAYGCNTGGAAYACNTTYATGAARGARGGNMGNTGGCARGAYCAYTAYAAYTTYCCNMGN ATHGGNYTNTGYGAYTAYMGNATHMGNCARCARCARAAYGTNCARCAYATGACNATHCAR TGYGTNYTNTCNATHAAYATGTTYYTNGARAARATGTAYYTNGTNYTNTGGTTYTGGYTN ATGATGATGYTNGTNTTYAAYTCNATHAAYYTNATHCARTGGYTNTAYMGNGGNYTNATG CCNCAYAAYGGNGARGARTTYATHMGNAARTAYYTNYTNYTNYTNGGNATHGAYTCNMGN GCNGAYCARAARYTNTTYGTNCARTTYGTNMGNMGNTAYYTNMGNACNGAYGGNGTNTTY ATGYTNMGNATHGTNGCNGCNAAYACNGGNCARATHYTNACNACNGAYYTNGTNAAYCAR YTNTGGAARATHTTYAARGARGGNCAYGGNGTNACNGARGAYGTNGGNGCNAARCCNAAY GGNGAYATHCCNCCNTCNGCNCCNGGNCCNGTNGTNGARGAYGAYGAYGAYAGYYTNCCN ATGGARAGYCARAGYAAYATHYTNYTNGTNTTYYTNGGNTCNYTNGTNYTNGCNAAYYTN GTNAGYTGYYTNCCNGCNMGNACNGCNGAYGAYATHYTNCARGAYGCNTCNGGNYTNGTN YTNGAYAARMGNCCNAARTAYATGGAYACNMGNMGNGAYYTNGAYGTNYTNAARGAYYTN GTNYTNATGAGYATHCARGARYTNGTNGAYGARGGNMGNYTNGARTCNGCNATHYTNCCN CCNGAY------GAYAARGARACNAGYAARCCNGTNGARAARMGNMGNTAYATGGGNYTN TGYATGCAYMGNCARGCNAAYCARTTYATHCCNTTYCCNTGYYTNMGNGCNGGNMGNATG AARTCNGTNYTNTTYYTNYTNYTNATHGGNTCNGCNGCNGTNYTNAGYGAYAAYTAYTTY TGY---CCNACNGARGGNGARAARTTYGARTGYTAYGARTCNYTNAARGAYTAYMGNGCN TGYYTNAGYGAYGGNMGNMGNGGNAAYTCNTAYGTNGTNTGYGGNAARTGYAARMGNAAR TGGGARTGGTGY------MGNACNGARGARATGAARAARAAYGGNGCNTAY---TAYTGY GGNGCNAAYTAYAARGCNACNCCNTGYACNGARAARAAYTCNTTYGTNGGNGAYATHTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNYTNACNATHTGYATHTTYGCNGGNAGYACNTGYGCNGTN TTYTAYATHCCNGGNTCNGTNGTNAGYTAYCCNAARATGGGNAARMGNGCNTTYTAYACN AAYGCNACNGGNAAYMGNTAYCCNYTNATGGGNMGNMGNTCNTCNCCNAGYGARGCNCAR AARGARGAYGGNGAYGCNCCNGARGTNGTNCARGARAGYGGNGARTAYAAY--------- ---------AARMGNGGNGTNTTYACNCARGGNCCNCAYMGNAGYTTYCCNMGNGTNGGN MGNTCNGGNAAYGCNAARYTNMGNAGYGAYYTNYTNMGNAGYYTNGCNGCNMGNYTNAAY GAYAAYGAYYTNGCNGARGGN---CCNGAYGGNMGNGCNGTNAARGARGCNYTNGCNGGN CARGGNGARMGNTCNGGNGCNGAYAAYTCNATHCCNYTNACNCARTTYYTNTTYYTNATH ATGGAYGARGAYGGNGAYGGNMGNYTNTCNAARGGNGARTTYTCNACNGGNATGGAYAAR GTNATGGGNCARAAYYTNYTNTGY---------------CCNGCNGTNTAYMGNGAYCAR CCNGTNAARGTNACNGTNGGNGTNGAYGTNACNTCNYTNMGNGARYTNGAYATGGCNMGN AAYGARATGGARYTNATHTAYTAYGAR---------------AAYTCNACNATHACNTGG AAYGARACNATGTCNCCNGTNCARCARGTNACNGTNCCNTCNAAYYTNATGTGGACNCCN GAYATGACNGTNTTYAAYGCN---GTNGGNCCNYTNGAYAAYTTYGCNCCNGAYTTYYTN GCNYTNCAYAAYTCNGGNAAYGTNTTYTGGGTN------CARMGNYTNAAYGTNMGNGCN YTNTGYTCNATGGARMGNTCNGARGCNACNCARAAYTGYYTNGTNAARATHGGNTCNTGG ACNMGNTCNGGNTTYGAYGTNACNYTNGCNGTNMGNTCNGARAAYGTN---YTNAAYGAY TAYGTNACNAAYCCNCARTAYGAYGTNYTNAAYGCNACNYTNACNAARCAYGTNACNTAY TAYAGYTGYTGYCCNGARCCNTTYGARACNATHAAYYTNGCNATGACNTTYGGNMGNMGN TCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNTAYACNCCNMGNTTYGTNGGNAAR MGNTCNGARGARTCNGTNGGNGARAARMGNGCNGARCARATGGTNTCNGARCAYTCNATH GCNAARMGNGCNYTN---------------------------------CCNCCNACNTTY GTNGGNAARCCNMGNTTYGTNGGNAARMGNAAYATHGARAAYYTNYTNYTNTCNTCNYTN GAR------TCNMGNGAYGCNGAYAGYGARACNGGNYTNGAYGAYGARGAYGTNTTYAAR MGNTAYATHCCNMGNTTYGTNGGNAARMGNGGNCCNCCNMGNTTYGTNGGNAARMGNTAY GTNCCNMGNTTYGTNGGNAARMGNGARGCNCCNMGNTTYGTNGGNAARMGNGGNCCN--- ------------------------------TCNYTNCARGCNTCNGARGARAARMGNGAY TAYGAYACNATHTTYGAYYTNYTNCAYAAYTCNGCNAARMGNMGNAGYCCNCCNMGNTTY GTNGGNAARMGNMGNGGNGTNGAYGCNTCNGARGARGTNGTNMGNMGNATGYTNTCNAAY YTNAGYMGNGARATHGCNATHAARGARYTNAARAARAGYGAYAARMGNTAYGGNMGNCCN ATHATHCCNGGNCARATHGGNAARMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARGARTTYGCNAARYTNAARAAR---AGYGGNGGNAAR YTNGTNTAYGAYMGNGCNTAYYTNATGGARYTNMGNGARTGYGCNTCNTCNCARACNAAR CCNGAYGGNYTNCCNAARYTNGAYATHATHYTNGAYAARCCNAAYCCNYTNATGYTNMGN CCNTCN---GGNGGNCCNGCNGAYTTYACNCCNGCNTTYTTYCAY---ATGGCNACNAAY CARMGNCAYGCNCCNCCNATHGGNAARAGYAGYAGYMGNGGNMGNCARMGNCCN---GGN CCNGGN---ACNCCNMGNGTNATHAARAGYATHTCNATGTCNAAYGAYACNAARACNYTN CAYCARAGYGARAAYCCNTGGAAR---------CCNACNAARAARGAYGARAARGAYGAR CAYAARACNYTNGARGCNGARATGYTNTTYATHATGAAYMGNYTNACNCCNACNAAYTTY GARAARATGGCNYTNGARATGAARAARYTNGGNGTNAARACNTAYGARGAYYTNCARYTN ATGATHAARATHTTYTTYGAYAARGCNACNATHGARACNAARTTYGTNGARGCNTAYGCN YTNYTNTGYAARGTNATGTCNGGNYTNAARGTNCCNCCNCCNGCNGAYGGNAGYGTNAAR GARCAYYTNGCNACNTTYMGNGTNGTNATGYTNACNAARTGYCARCARGARTTYGARGCN GAYAARACNATHATHTTYGARGAYCCNGARGARAARAARAARAARYTNGARGCNGARTAY CCNGARAAYACNCCNGGNMGNATHGARAARATHGAYAAYATHYTNTAYCARATGAARYTN AARMGNATGAARTTYTAYGGNAAYATHMGNTTYATHGGNGARYTNTTYAARYTNAGYATG YTNACNGARAAYATHATGCAYGAYTGYATHTAYMGNYTNYTNAARGCNMGNGAYGAYGAY TCNYTNGTNTCNYTNAGYAAYYTNYTNACNACNGTNGGNMGNAAYYTNGARACNGARAAR GCNAARCCNMGNATGGAYCARTAYTTYTCNCARATHGCNAARATHGCNGAYGARMGNAAR TCNMGNATHAARTTYACNYTNMGNGAYGTNATHGARYTNMGNCARAAYCAYTGGATHCCN MGNAARGARGCNACNGGNCCNAARAARATHAAYGARGTNCAYAARGAYTTYGCNCARGAR CARGCNMGNAAYCARTTYYTNGCNTCNCARCCNCCNCCNCCNMGNAAYGAYAGYTCNCAR GCNGGNAGYMGNMGNGGNAGYMGNCARMGNCCNGAYGAY---AARCCNAAYGAYGARGGN TGGAAYACNGTNAGYTCN---AARTCNGTNMGNATGATHGAYGCNTCNAARATGAARTTY TCNTCNAARAGYGTNGTNGAYGAYAAYATHCARYTNGGNCCNGGNGGNGGNGTNCAYMGN CARACNYTNTGGGGNMGNGGNAGYCAYGGNGGNGCN---CARCCNTCNCARGAYGAYMGN CCNTCNGTNGCNTCNAAYMGNTTYTCNGCNYTNACNAGYGAYGAYTCNMGNMGNCARTTY CCNMGNTCNCCNTCNMGNGGNGARGGNGGNGCNGCNMGNGGNATGMGNCARGGNCCNACN GTNGGNCAYGGNMGNGGNAARATHATGTCNMGNTCNAGYCARGARGGNGAYAARMGNGAY YTNTTYTCNAAYGCNMGNTCNTAYATGGGNGGNMGNTCNCARAAYTCNAGYMGNGAYAAY AGYTGGAAYMGNGAYGAYMGNMGNCARTTYATGGGNTCNMGNGGNTCNGGNGAYMGNGAY AAYCCNATGATHMGNAGYGAYAGYAGYGTNAAY---GTNGARGARTTYMGNGCNCCNGCN CCN---------GCNGTNAARCARATGACNGARTCNGARATHGARACNAARGCNAGYAAY ATHYTNGAYGARTAYYTNAAYATHAARGAYATHAAYGARGCNAARYTNTGYGTNAARGAR YTNACNGGNCARAAYATGATHTAYTGYTTYGTNACNGCNTGYATHAAYAAYGTNYTNGAR AARAARGARGCNTCNMGNCARYTNACNGGNAAYYTNTTYCAYGARYTNGTNAGYAAYAAY ACNYTNAAYTCNAAYATGTAYATHAARGGNYTNAGYGARGTNYTNCARTAYGCNAGYGAY ATGGTNGTNGAYATHCCNACNYTNTGGAAYAAYYTNGCNCARGTNATHTGYCCNYTNYTN GTNGGNGGNTCNYTNCCNTGGTCNAARYTNAARCARGCNYTNAGYCCNCAYYTNGAYAAY AARGAYGGNGGNAARYTNYTNGCNGCNATHYTNTCNAAYTGYGTNAAYATHCARGGNGAR AARGARGTNTCNCARCARTGGCARAAYAGYGGNYTNAGYTGGTCNTCNTAYYTNAARCAR GAYGAYATHAAYGARTTYGTNGCNGAYAARAARYTNGAYTTYACNYTNGGNGGNTCNCAR TCNTCN---------------------------------------------YTNGGNTCN GAYYTNGARGARATGATHMGNAAYMGNAARAGYAGYGAYGARGTNGTNTCNTTYATHGAR AARACNGTNMGNAAYMGNTCNGAYAAY---AGYTTYATHMGNGCNYTNACNACNGCNGTN GTNAGYGCNTCNYTNTCNGARTCNAARGAR---YTNAARTTYAAYGARGAYGTNYTNAAR AAYTAYAARGAYGTNATGCARAARTAYYTN---GGNAGYACNGTNGARYTNCARYTNCAR GCNYTNTAYGCNATHCARACNYTNATHGCNAARYTNGARCAYCCNTCNGGNYTNYTNTCN AARYTNTTYGARYTNYTNTAYTAYGARATHTCNGTNGARGARGARGCNTTYTAYAARTGG GARAAYAGYAGYGAYCCNCARGARCARGARGCNAARGGNATHTGYATGATGCARGTNMGN CARTTYTTYATHTGGYTNAARGARAAYGARGAYCCNGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYCCNYTNGGNGAYGAYAGYATGGARGCNTTYATHAAYYTN GARAARTTYYTNGAYGARAAYTCNYTNTTYGAYGAR------GAYGGNAAYYTNACNGTN CCNAAYATGGARGCNGARGTNAARCCNGTNATHACNYTNGCNCCNGARCCNGARTCNGCN ATHCCNCARGARGTNGTNCCNACNCCNGCNCCNACNCARACNYTNAARAGYCCNGCN--- ---------AARMGNAARMGNGCNGCNMGNTCNAARGARGGNGTNAARACNAGYYTNTTY GARATHCCNGTNMGN---------------GARAGYGARAARGAYTCN------GTNYTN GTNACNATGGAYAGYGARYTNGAYCAYGAYTAYAGYTTYAARMGNCARMGNYTNTCNTCN TCNGGNAGYACN------------TCNAGYGAYACNAARMGNGTNAAYACNACNAGYGAR CCNMGNCCNAGYACNAGYACNTAYCCNGARGCNGAR---------ACNGARAGYGTNTTY GAYGAR------------------TCNATGGAYAARCAYACNATHMGNMGNATHAARAAY AAYCAYGCNTCNAARMGNTCNMGNGARCARMGNAARCARAARTTYGTNGAYATGGAYGTN GARGCNGARGARYTNGTNATHAARAAYCARGARYTNMGNGARAARATHGTNGARYTNGAR AAYYTNGCNAARGARATGAARCARGTNYTNGTNGCNAARATGACNGGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNAAYTCNGGNCARGAYAGYAAYCARGARGTNAGY---AGYTCNGAYATH GCNGARTCNGGNTGYYTNTCNCARCCNCCNAARGTNCCNGCNGCNAGYCCNTTYAGYAAY GCNTTY------TAYGGNAAYACNCAYACNGCNGGNATGTAYTCNAAYCCNTTYGTNACN MGNCCNCCNTTYAARTCNGAYGTNGTNTCNACNGAYCARTCNAGYTCNGARGTN---MGN GARAGYYTNATHGCNCCNAGYMGNYTNAAYGCNGCNGTNAARMGNGAYAGYTCNGARGCN GARAGY---GAYAARAAYAGYTAYTCNAARTCNTCNATGYTNGCNCCNCCNAARYTNACN GGNGCNGTNTTYGGNGGNGGNGCNAGYMGNCARGAYACNCCNAGYTCNACNTTYAAYTCN TAYAAYTCNTTYCAYATHMGNCCNTCNGTNTTYTCNGGNCCNTTYGARTCNGGNAGYGGN MGNGGN---GCNCCNYTNYTNAARCCNGCNAARYTNCCNGAYCCNACNAARACNTGYGAY GGNAARGCNGAYTCNGCNAGYGARTCNGAR------AGY---------GTNGAYAARTCN GGNGARGCNTCNTCNGCNAGYGAYMGNAGYGGNGGNGCNGAYGGNACNGTNGGNGGNAAY GARGTNTCNTCNTCNTCNTCNACNTCNTCNTCN---------GTNCCNCCNTCNCARGCN GAYGCNGARGGNGCNGTNGGNGGNGARAGYACNCCNTAYAAYCARGAYATHGTNCCNGAY ATHAAYAARAAYAAYMGNYTNAARGAYTCNTCNGGNGTNTCNAGYAGYTCNCARTCNTTY GTNTTYGGNAGYAAYYTNTCNCARMGNGTNACNGGNATHACNGCNGARTCN--------- ---GARGCNTCNGCNACNTCNGGNTTYGTNTTYGGNGARTCNYTNAGYTCNMGNGCNGTN GTNGARACNAAYGGNTCNACNCARGCNCAYAARGAYGARGARAGYGAYTCNGARTCNAGY AAYAARYTNAAYCARACNYTNGARGARTCNGCNMGNGARTAYCARGCNAARCAYGARATH AARACNGARYTNAARGARGTNGARACNATHACNGGNGARGARGARGARTCNAAYGTNYTN CARGCNAAYGCNAARYTNTTYTTYTTYGARACNAGYAAYGARTCNTGGGTNGARMGNGGN MGNGGNACNATHMGNYTNAAYGAYATGTCNGCNMGNGAYAAYACNAARTTYCARTCNMGN YTNGTNATGMGNACNCARGGNAGYYTNMGNGTNGTNYTNAAYACNAARATHTGGCCNGGN ATGTCNYTNGARMGNGCNTCNCCNAARTCNGTNMGNATHACNGCNATGGAYACNGAYGAR TCNATHAARATHTTYYTNATHACNGCNAGYACNAARGAYTCNGARAAYYTNYTNMGNGCN ATHGAYTGGMGNATHCARCARYTNAARATHCARGARGARCCNGTNMGNCARYTNTCNGAY TCNMGNACNGGNGAYAARMGNAARGCNGAYGAYTCNGAYTTYGARCAYCCNGTNAARAGY AARAARGTNAAYAAYTCNCCNGAYCARGGNATHTCNATHACNAARAARGARGARTCNGAY AGYAGYGTNCARGAYCCNGARACNGARGCNTCNTGYGARAGYCAYTCNTCNTCNYTNACN ATHAARTCNGARTCNGAY------------------------------------------ ------------------------------------------------------------ ---------------------------ATHATHYTNYTNGAYGTNYTNYTNYTNCARAAR TCNGCNTAYGCNCAYYTNYTNTTYAAYATHGARATGAARTCNCAYTGGAARTCNGCNGTN YTNYTNTGGGTNGTNGARGCNTTYGTNAARYTNATHCARCARMGNTCNGARCARGCNGAY TCNCAY------------------ATHCCNGAYTCNTAYGTNGGNGTNGAYYTNTAYYTN AAYTAYATHATGGCNGTNATHGAYYTNYTNGTNTTYYTNATGTGYGTNYTNGCNATGYTN ACNATHMGNAGYYTNYTNYTNACNMGNAGYYTNAARYTNYTNAAYCCNTTYTTYATHGTN AARGCNGTNYTNYTNGCNAAYYTNGGNTCNATHYTNGCNATGCCNGCNGTNYTNTGGGGN AARTCNTAYAGYCCNATHYTNGTNTGGYTNGGNCARGGNTTYGTNTGYATGTCNGCNYTN CARGCNYTNMGNGTNGTNGTN---CCNGGNTCNCAYAARACNGTNTTYGCNGCNTTYGCN GTNGCNTTYGGNATGACNGTNMGNGCNYTNYTNTCNGAYGCNYTNAAYCARTGGYTNCAY CAYTTYTAYATGYTNCAYGTNACNYTNAARGARGGNMGNGAYYTNGTNATHMGNGAYAGY TGYGGNACNAGYGAYCCNTAYGTNAARTTYAARTAYGGNGGNAARCARGTNCAYAARAGY MGNACNATHYTNAARAAYYTNAAYCCNAARTGGGAYGARCARTTYGTNATHCCNATHGAY GAYATHACNAARCCNYTNAAYGTNAARGTNTAYGAYTAYGAYMGNGCNTGGAAYGAYGAY CCNATGGGNGGNGCNGAYYTNGAYATHTCNACNATHGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CAYMGNGCNGTNATH GARTTYYTNACNGCNGARGGNTGYTGYTCNGCNATHATHCAYCARMGNATHAARACNGTN TAYGGNGARATGTGYATHACNAAYGGNGTNGTNGGNAAYTGGGTNMGNATHTTYMGNGGN GAYGAYCCNAARGAR---------------------------------ATGGCNTCNAAR ---YTNTCNCAYCCNGTNGTNAARTCNYTNCARGGNMGNACNTTY---GCNGCNGCNGCN GCNGCNCARCCNAARGTNTCNCCNGAYAGYCAYTCN------------ATHAARAARYTN TCNAAYGGNATGCARGTNGGNGTNYTNGCNTCNAAYTCNCCNATHTCNMGNATHGCNGTN GTNGCNCARGCNGGNTCNMGNTTYGARAAYGGNGAYAAYYTNGGNGTNTCNCAYTTYYTN MGNYTNTCNTCNMGNYTNMGNACNGARAAYATGTCNAGYYTNGCNYTNACNMGNACNGTN CARCARYTNGGNAGYGAYGTNTCNATHYTNGGNACNMGNGARTAYATHTAYTTYAARAGY AAYGTNAAYMGNGAYTCNGTNGGNAGYATGGTNMGNATHYTNCARGARATGACNACNAAR CARGCNTTYAARCCNTGGGARGTNTCNGAYGCNCARCARGAYAARGAYGGNATGYTNYTN GAYYTNGCNATHTAYCARTCNMGNCCNCAYGTNMGNGCNGTNGARYTNYTNCAYTCNGCN GCNTTYMGNAAYACNYTNGGNAAYTCNYTNTAYGCNCCNGAYCAYGTNGTNGGNAARYTN ACNTCNGAYCARGTNATGCAYTTYACNAARACNAAYTTYAGYGCNGGNMGNATGGCNYTN ATHGGNATHGGNGTNGAYGGNGCNGARYTNGARAGYYTNGCNTCNGARTTYGARCCNTTY GCNTCNGCNGAYGCNCCNGTNGARAARTCNAGYTAYTAYGCNGGNGGNGARATHMGNGAR AAYACNGGNGGNGAYATHACNTAYGTNGCNGTNGGNTGYGGNGGNCCNAGYYTNACNAGY AARGAYYTNATHGTNGCNGARGTNYTNMGNCAYATHYTNGGNTGYGGNGCNCAYATHAAR TAYAGYGAYGGNACNACNGTNCCNAGYYTNGCNAARGCNGCNGCNGCNGCNACNAAYGCN GCNTTYCAYGTNTCNTGYYTNAAYGCNACNTAYACNGAYAAYGGNYTNTTYGGNTTYACN GCNGTNGCNCAYGCNTCNCARATHGARAARGTNYTNCARGCNGCNGGNAARCARTTYAAR GCNYTNGARAGYGCN------ACNGAYGCNGAYGTNGCNMGNGCNAARAAYCARYTNAAR GCNGARYTNTGYATGCARTTYGARCAYCCNGAYATHYTNYTNAAYTGGYTNGGNGARCAR GCNYTNAAYGGNGGNGARGCNGTNATGCCNGAYGAYATHTAYAARATGGTNGAYGCNGTN ACNGGNAGYGAYGCNAARMGNGTNGCNGGNGCNATHYTNAGYGCNAARCCNTCNATGGCN GTNACNGGNAAYACNTCNMGNGTNCCNTAYYTNGAYCARYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARCCNGCNCARGARCCNGCNCCNGCNCCNGCNGAR GARAGYAARCCN---------------------------------GARGARACNCCNGCN CCNGCNCCNGTNGARGARACNACNAARGARGAYCCNGARCCNGARCCNCCN--------- ---------GCNCCNGARCCNGCNACNCARGARCARGARGCNGCNCCNGARCCNCCNGCN CCNGARCCNCCNGCN--------------------------------------------- ---GCNGARGARGCNCCNGCNGCNGARGARGCNCCNGCNCCNGCNGCNGARGAR------ ---------------GCNCCNGCNGCNGARCAR--------------------------- ------------------------------------------------------------ ------AGYCCNCCNGCNGCNAGYGARGARAGYTCNCCNGCNAARCCNTCNGARTCNGCN GARTCNGCNGARACNGGNGCNGCNGARGGNTCNGCNGCNGARACNGGNGARACNGCNGCN CCNAGYGARGARTCNGCNCCNTCNACNGTNMGNACNGARGTNAARTGGGARAAYGGNGGN GARACNGTNYTNGTNAGYGGNACNTTYAAYAGYTGGCARGARCAYATHGCNYTNTCNAAR GARGGNGAYATHTTYACNGCNTTYYTNGAYYTNCCNGTNGGNGARCAYYTNTGYAARTTY ATGGTNGAYGARCARTGGGTNGTNAAYAARAAYYTNCCNGTNMGNTCNGGNGAYGAYGGN CARGARAAYAAYGTNATHYTNGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATGGAYAGYGAYATGGARATHGTNGGNYTNTAYCARCCNCCNYTNCARTGYCCN GARGGNMGNTGYAARGAYYTNYTNCCNACNTTYATHTAYTGYGTNGTNATHCCNGCNGCN GTNYTNGTNGTNATHTTYATHATHATHATHGCNATHATHTGYTGYTCN---AARGCNTGY AARTGYCARAARTAYTCNTCNYTNGTNACNGARACNGAYGAYATHCARATGGARAGYTAY AAYACNATHMGNMGNGCNTCNATGGGNYTNMGNCARATGTCNCARAAYMGNGARACNCCN ATGACNGAYAGYMGNGARAAY---TCNATGACNYTNGAYMGNTCNTAYMGNMGNACNMGN MGNCARMGNGAYTCNTGYCAYTCNGCNCCNGGNACNYTNCARMGNCAYCAR--------- ------------------------------------MGNAAYMGNTCNGGNYTNGTNGAY CARYTNGCN---CCNCCNCCNCCNGCNTAYAGYATGCAYTCNAGYGARATHTTYTTYGGN TCNGARTTYYTNTCNGAYGAYMGNATGCAYACNAGYGTNCARTAYGARGAYAGYCARGAR CAYAAYGGNAGYAGYGCNCARGCNYTNYTNTAYMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CCNGTNTTYTCNTAYAGYTGYYTNATH GCNYTNGCNTCNYTNAAYAARTGYTTYGCNAARGTNGAYAAYCCNAARYTNAGYCARGGN GCNAARAARGGNTGYYTNTGGGCNYTNAAYCCNGCNAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNYTNMGNACNGTNCAYAGYGTNATHCAYACNTCN CCNCCNAARYTNYTNAARGARGTNGTNYTNATHGAYGAYGGNAGYGAYTAYGAYTTYYTN GGNGARAARYTNGARCAYTAYATHAARCARTTYAAYGGNYTNGTNAARYTNTAYMGNAAY CCNGARMGNTAYGGNYTNATHACNGCNMGNACNAARGGNGCNGARCAYTCNACNGGNGAY GTNATHGTNTTYYTNGAYGCNCAYTGY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TGGCARYTNAARTGYCARAAYYTNGARAARGTNATHAARAGY YTNTCNAARCAYTGYTTYACNGTNGTNGARAARCAYGARCARYTNYTNACNTCNCAYAAR AARAAYGARGARCARTAYAAYAARYTNAARACNAARTTYCARGAYAARGGNGARCARATH AARAARGCNMGNGAYGTNYTNATHCCNGTNTCNAAYGARYTNAARACNYTNMGNGARAAR TAYGARATHGCNGTNMGNTGYCARATHGARGCNGARTCNTAYGCNGTNAARACNACNAAY AARAAYAARMGNYTNACNMGNCARAGYGARATGTGGGGNGCNAARYTNGGNGCNATHAAY ATHACNGARATHAAYATHGAYGAYAAYGARGAYGARGGNGAYGARGARAARGARTAYATG ACNAARYTNGGNCARCARATHGAYCARYTNGARGARGARAARAGYGTNYTNACNGTNCAR GTNMGNGARYTNAARGARAAYTTYGARATHGARMGNGAYGCNAARMGNGAYYTNMGNGAY ATGGTNAARCARYTNAARGARGAYYTNMGNAARMGNAAYGARGTNATGAARGARCARGAR GARATGYTNGCNCARGTNGCNACNGCNTCNGARAARGTNTAYCARGARTAYGARAGYATG GARCARACNTGYATGAARGARATGACNGTNMGNTAYGARGCNGARATHGTNGCNCAYAAR YTNACNACNGARMGNGAYCARGCNMGNMGNGARAGYTCNYTNGCNYTNAGYAARGTNTCN GAYAAYAARAARYTNATGGARGCNATGATHCARATHCARGAYYTNAAYACNCARACNGCN GGNYTNAARGAYGARTAYGARMGNAARATHCAYGAYYTNGARGAYCARATHAARACNTTY AARGARGTNYTNAAYACNGAYAAYYTNGCNGARGARAAYGARGARYTNCARCARGAYAAR AARACNYTNGARGARCARYTNAARGCNAGYMGNGCNGARGTNGARAARYTNCAYGGNGAY TAYACNAARYTNATGGARACNTAYAARACNATGGARAARAARTAYGARAAYGCNATHAAR CCNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCN------CCNGCNATGAARACNGGNGGN TTYYTNCARMGNATHGTNGGNMGNAARGGNCARMGNGARMGNGCNAARGARCARYTNAAR AARGGNGGNGTNTCNATGAAYGAYAAYCAYACNAARGCNGTNGAYGARATGATGAARMGN ATHMGNAGYGGNAAYGTNGGNYTNMGNCCNGTNYTNCAYAARCARACN---GAYYTNAAR TCNYTNCCNGARCARGARAAYCCNAGYGCNATGYTNGARYTNCARGGNYTNYTNAAYAAR ATGAARAARAGYMGNAGYGARGAYGAYYTNTCNYTNTTYGARGARGARACNGGNGTNAAY GARCARTCNGARYTNGGNAARATHYTNAARAARMGNMGNCAR------------------ ---------GCNAAYACNGARAAR------------------GAYCCNTCNCCNMGNCCN ATHCCNMGNCCNMGNCCNTAYCCNMGNAARYTNTCNYTNATHAARGAYGARGAYGARGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GTNGGNGCNTTYGTNCARGAYGAYGTNTAYGGNYTNGGNYTNTAYCARTCN TTYMGNCARGARGCNGARACNCARMGNATHTGYGTNGARGAYGCNTTYAARYTNAAYGAY TAYACNAGYGARGCNAARATHGARGCNGCNYTNYTNAARYTNGGNGGNAAYGARGTNGGN GTNGCNGTNYTNTTYGCNACNTCNTCNGTNATHACNAARATHYTNGGNATHAARAARATH GAYAARTTYCAYTTYGTNGCNAGYACNTCNTGGGGNYTNAAYCCNGCNATHYTNGAYCAY GAYYTNGGNGARATHGCNCARGGNTCNTTYATHYTNGGNCCNACNCARCCNAAYTTYAAY TTYGGNYTNGARAGYCAYYTNGARAAYYTNAAYGCNTTYGAYATHAARGCNACNGTNTGG CARCARGARTTYTGGCARGGNTTYTTYGCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TCNAAYGCNTCNYTNTCNAGYAAYAGY AGYTTYAGYACNCARGAYGCNGARGCNCARYTNAARGCNATGYTNTTYGGNGGNCCNMGN GAYTCNGCNTCNTCNAGYGGNACNGCNTCNCCNGCNGCNYTNCCNTCNAGYTTYCARAAR MGNGTNAARACNGTNGCNGARYTNGARGCNGAYATGCAYCARAAYACNCCNCARAARACN GCNAGYCCNGTNACNACNTCNCARTCNAGYAARGAYAAYAARGAYATGACNGCNTTYAAY AARTTYYTNATHATGATGAAYGCNGGNTCNGARGCNAAYCARAAYGCNCCNMGNAARGAR CCNCCNCCNCAYTCNTCNGAYGGNTAYGGNATGGTNCCNAGYCAYAGYGARTTYACNCAR GCNYTNATHMGNAAYAARGARCAYCARATGCAYYTNYTNCAYCARTCNYTNAAYYTNGCN CCNCARGCNATGTCNACNCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNCAYAGYTCNTCNGTNGAYGARMGNTCNMGNGCN TCNACNGTNTCNTCNGGNGARGGNAGYATHGTNGARGARTCNTCNYTNCARAGYYTNMGN TCNACNACNAGYTCNGTNGTNTCNAAYTTYAGYAAYTCNTAYCCNGCNYTNACNTCNTCN GTNACNGTNACNYTNCCNCCNGTNAGYYTNGARCARTCNTCNTCNCARGAYAAYMGNGGN GTNMGNCARMGNCCNGTNTAYGAYCCNTCNCCNACNAGYMGNATGGARAGYTCNTTYTAY ATGGTNGAYACNATGCCNAGYGCNGTNCCNMGNGGNAARGGNAAYGGNGCNTAYYTNCCN CARACNGTNTTYYTNGARAGYACNACNTGYCARTTYTCNCCNCAYAAYATHCAYACNGCN CARGTNYTNCCNGGNGTNACNATHYTNTTYYTNTCNCARGCNCCNMGNACNATHATGGCN GAYCCNYTNTAYCARGTNATGAGYAAYATHCARGAYYTNATHTTYGGNMGNMGNACNAAR YTNCCNMGNTCNMGNAGYYTNCAYGTNTAYGARATHATHAAYTCNYTNYTNAGYAARYTN CAYAAYAGYYTNMGNAARTTYAARGGNMGNGARMGNCAYYTNATHTCNGAYATHCAYAGY MGNTGGGARAARGARGAYGTNAARCAYAARYTNYTNGARTAYYTNGARAARGARTCNAGY GTNCAYATHCCNCCNGARGTNGARTCNCCNYTNACNGARATGTAYAARAARYTNMGNGAR YTNTTYACNYTNYTNTTYYTNTAYCCNCCNCCNGARAAYMGNCARYTNAARGARTCNYTN TCNCARYTNMGNGTNGCNATHAAYGCNGARYTNYTNGAYTAYMGNGARTAYYTNAAYGTN AARTCNCARMGNAAYATHACNATGACNAGYTAYTTYGAYAARTTYCCNGGNYTNGTNTAY TTYATHTTYGTNGAYMGNMGNYTNCAYCARATGACNGCNCCNTCNYTNAAYATHTCNTTY AAYGAYGGNGARGARGTNAAYGCNAGYTCNTAYYTNAARGGNAAYATHTGGMGNATGCAY CARGTNATGATGAARAARGTNATGACNGGNTAYACNACNGTNYTNYTNMGNGARGGNGAY TTYTAYTAYTCNTAYTTYYTNTGGTTYGARGAYAGYGCNGGNAAYCCNYTNCCNGTNCAR GARAAYTTYAARCCNTCNAAYAAYTTYACNTAYCCNGGNATHYTNTGYGGNTCNTTYTAY AARGARYTNYTNYTNCARTGYTTYCCNCARGTNYTNATGAAYTCNGTNTTYTGYTAYGAR ATGTTYYTNATGCAYGTNGGNTGYATHCAYCCNCARTAYATHGCNACNCARTGYAARMGN YTNGCNGCNGARYTNTGGGARATGTCNGGNGAYGCNTAYTCNACNYTNAAYYTNTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNTCNAGYAGYCARGGNTCNMGNATGAARMGN TCNGARMGNCAYATGATGMGNYTNAARAGYATHATHGCNMGNGTNYTNAARGARAARGAY GTNAARGARGGNGAYGCNATHTAYGAYGCNTGYTCNAARAAYYTNYTNAAYGTNAGYATH ATHYTNYTNAARGCNYTNCCNAAYTCNAARAAYYTNAAYAAYGARATGAARTCNGTNGTN TAYGARCARGTNCARCARATHATHAAYYTNGARAARMGNMGNTCNGGNATHGCNATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYATGGAYTTYYTN------------ ------------------------------------------------------------ ------------------------------GARGTNTCNYTNTGGGGNAAYAARTGYGAY YTNTCNATHTCNGCNGGNCARGARAAYAAYCARACNGARAAYCCNYTNCARCARYTNGCN CAYYTNAARTCNTAYATHYTNAARAAYGAYGCNMGNAGYGTN------------YTNGAY YTNYTNMGNMGNACNGGNGAYAARGGNGCNAARGTNTCNATHGTNYTNGAYAAYGCNGGN TTYGARTTYGTNACNGAYYTNTGYYTNTCNCARTTYYTNYTNGCNAGYGGNYTNGCNTCN ACNGTNCAYTTYCAYGGNAARAGYATGCCNTGGTTYGTNTCNGAYGTNACNGCNMGNGAY GTNGARTGGACNYTNAAYCARATGGCNCARATGAAYCAYATHGGNATHAGYMGNYTNTGY CARGCNYTNAAYGAYCAYATHAAYAAYGGNGCNATHACNTTYGARTAYAAYACNTTYTGG ACNATGGCNCAYCCNTTYTGGCARATGGARTCNTAYTGYCCNGARYTNTAYTCNAGYYTN TCNMGNAGYGAYYTNGTNATHTTYAARGGNGAYYTNAAYTAYMGNAARYTNGTNGGNGAY YTNAAYTGGGCNACNACNATHGAYTTYTCNCAYGCNYTNCARGGNTTY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AAYGGNCAYTTYACNAAYGTN CCNACNACNGTNAARAAYYTNGGNGAYACNTCNMGNGTNGAYTAYATHYTNGARAAYTCN TCNCCNGCNACNTCNACNATHATHCARAAYACNYTNGGNAAYTCNAARAARAAYTTYGTN AGYGAYTCNGGNGARGTNAARCARATHGTNCARATGAARGGNYTNATHTCNTCNATGAGY AARGGNYTNGARTCNACNCARAGYAARGTNAAYAAYAGYGARGCNGTNYTNGARYTNYTN GARGTNGARGTNTCNAGYYTNMGNGARMGNGTNGCNTCNYTNGARAARGCNGARATGYTN MGNACNTTYCARMGNGARGARGARGARMGNATHGARCARGARAARYTNGARGCNGARGAR GARGAYCARYTNTTYGTNTTYYTNTTYGGNTTYATHTGYNNNNNNNNNMGNNNNNNNNNN NNNNNNNNNNNNNNNNNNMGNAARMGNNNNMGNAGYMGNGAYMGN--------------- ---AARMGNTCNMGNAGY---------------------AARGAYMGNAARTCNMGNAGY MGNAGYMGNGAYAARMGNMGN---MGNGARMGNGAYMGNGGNMGNMGNMGNAGYMGNAGY AARAGYMGNAGYMGNGAYMGNMGNMGNMGNAGYMGNTCNCCNGGNMGNMGNMGNAGYMGN AGYCCNATHMGN---GARMGNTCNCCNGARYTNACNGTNGARGARMGNGAYGTNMGNACN ATHTTYTGYATGCARYTNTCNGCNMGNATHMGNCCNMGNGAYYTNGARGARTTYTTYTCN TCNGTNGGNAARGTNMGNGAYGTNMGNYTNATHACNGAYAAYAARACNMGNMGNTCNAAR GGNATHGCNTAYGTNGARTTYGCNGAYCCNGARTCNGTNACNYTNGCNATGGGNYTNACN GGNCARAARYTNYTNGGNGTNCCNATHATGGTNCARCCNTCNCARGCNGARAARAAYMGN GCNCARCCNGCNGCN---CCNGCNCARGCNCARAARCCNGCNGCNGARGGNCCNYTNMGN YTNTAYGTNGGNTCNYTNCAYTTYAAYATHACNGARGAYATGYTNMGNGGNATHTTYGAR CCNTTYGGNAARATHGTNGAYATHAARATHATGMGNGAYCAYGAYACNYTNMGNTCNYTN GGNTTYGGNTTYATHAGYTTYGCNAAYGCNGAYGAYGCNAARAARGCNYTNGAYCARYTN AAYGGNTTYGARYTNGCNGGNMGNCCNATGAARGTNGGNCAYGTNACNGARMGNTCNGCN GAYGGNGGNCARGGN------GCNCARAAYGGNGTNGGNGGNCARYTNGAYACNGAYGAR ATGGAYMGNGCNGGNATHGAYYTNGGNGCNACNGGNMGNYTNCARYTNATGGCNAARYTN GCNGARGGNACNGGNTTYCARATHCCNCARTAYGCNGCNAGYGCNYTNAAYATGTCNGCN CCNGCNCCNGCNACN---GGNYTNGCNGGNGCNGCNCCNGCNAGYACNYTNGGNYTNACN TCNACNYTNCCNACNCCNGCNGCNGCNGCNCCNCCNACN---CCNGCNGCNACNGCNACN ACN------------GCNCCNCCNATHGCNACNCARTGYTTYATGYTNTCNAAYATGTTY GAYCCNACNTCNGARATHMGNYTNACNTTYGAYCARGARGTNMGNGAYGAYGTNATHGAY GARTGYAAYAARCAYGGNGGNGTNYTNCAYATHTAYGTNGAYAARAAYTCNCCNCARGGN AAYGTNTAYGTNAARTGYCCNAGYATHTCNGCNGCNGTNGCNTCNGTNAAYTCNYTNCAY GGNMGNTAYTTYGCNGGNMGNYTNATHATGGCNAARGCNGCNCARTTYGAYGAYAAYTTY CAYGCNCARAARCCNGAYATGGCNCCNTCNMGNGCNCAYTTYAAYGTNAGYGARGARYTN MGNYTNTCNAAYATGTCNYTNAAYAARAARAGYATGGTNATGGAYGARGAYAGYTTYGAR GCNAARTTYYTNAARTGYGGNATHTGYAARGTNMGNTTYACNCARAAYTCNYTNCCNMGN YTNYTNCCNTGYCAYCAYTCNTTYTGYCARGARTGYGTNATGCAYYTNTAYMGNACNGCN AARGARCAYMGNGCNAAYYTNCARGCNTCNYTNMGNACNACNACNTCNCCNYTNACNACN GTNAGYGTNCCNTGYCCNACNTGYMGNTCNAAYTTYATHGCNACNGARGARAAYGTNCAR AARYTNCCNACNGAYCAYMGNATHGTNCARYTNATGGAYTTYGTNAAYCAYACNGARMGN TCNACNATHTCNTAYTGYTCNCARCAYAGYYTNCARCCNYTNAAYTTYTTYTGYGARCCN TGYGTNMGNCCNGTNTGYMGNGAYTGYACNATHAARGAYCAYAARGARACNGAYGGNCAY YTNGTNATGGAYYTNGAYGCNGCNATGGARAARTAYACNCCNGTNATGGAYACNGCNATH GCNGARATGGAYGCNGARGCNATGGGNATGGARGARAARAARYTNGCNYTNGARTCNGTN TCNCARACNATGGAYTCNGTNAARACNAARYTNYTNGCNGARAAYAARTCNTGYATGGCN MGNYTNMGNAAYYTNATHTCNGARMGNGARAARGCNYTNGARGCNAARATHCAYYTNGAR GTNGARAARGARAARMGNAARYTNAGYGARAARAGYGGNGCNYTNGTNGARMGNAARAAR MGNYTNGARGARCARTCNGCNMGNYTNAARATGGCNAARAARGARGGNAAYGTNGARGAY ATHTTYYTNATHCAYCARGARGTNAARGARTGYATGGCNGAYGCNCCNATGAARGTNMGN GARGTNGAYGAYGGNATHATGACNTCNTTYGCNYTNAGYACNMGNGAYGARTCNYTNYTN GCNTCNMGNATHAAYCAYTTYGGNGARYTNACNAGYMGNGTNGARACNACNGCNTCNAAR ACNAARTCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARAARYTNAAYTCNTTYATHGAYTTYGAYTAY YTNGAYTCNYTNATHTCNACNAAYGCNAGYCARTAYGCNTCNACNATGTCNYTNGCNCAR TCNACNTCNAARTCNTCNATHACNTCNAAYTAYGGNGCNACN---MGNAARCCNMGNATG CAYGCNMGNYTNAGY------------AARCCNCAYTTYMGNACNTCNTCNCCNAAYAAR ACNCARTCNCCNAAYTCNTCNCARGARTCNCAYATHATHGAYGCNGTNGCNGAYGCNCAR ACNAGYCCNMGNGTNAARGGN------GGNYTN--------------------------- GGNAARGAYAGYAARMGNCCNAGYGAYGCNYTNACNCCNATHMGNGARATGACNAGYGAR GAYGARGAYGARGAYATHGGNAAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GTNCARAAR TCNCARAGYMGNMGNATHAARAGYACNAARCAYYTNAARCARGTNTAYGAYCCNTTYAAR YTNGTNCCNTGYYTNTCNTTYACNTCNGARAAYAARGARCCNTAYAARATHGARATHTTY AAYACNGCNYTNTCNATHATGGAYATHCAYTCNCAYATHTCNAARACNGARGTNATHGGN ATGYTNGGNGGNMGNTTYAAYGTNGAYACNAARTGYYTNACNATHAGYATGGCNGTNCCN TGYAARAGYATGAGYACNGGNATGCARTGYGARATGGAYCCNGTNTCNCARACNYTNGCN AGYGARCARATHGARGAYGTNGGNATGTCNGTNGTNGGNTGGTAYCAYTCNCAYCCNTCN TTYAGYGCNGAYCCNTCNGTNMGNGAYATHGARACNCARCARAARTTYCARTAYTGG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TGGTAYGCNATHCCNCCNGARCAYGGNCARMGNYTNGARMGNYTNGCN CARGGNTTYTTYCCNAGYAGYTTYGGNCARTGYCCNGCNTTYYTNMGNCAYAARATGTCN YTNATHTCNCCNCAYATHYTNAARAARTAYTCNATHCCNGTNAAYAARATHACNCARGAY GCNGGNGAYATHATHATHACNTTYCCNTAYGGNTAYCAYGCNGGNTTYAAYCAYGGNTTY AAYTGYGCNGARTCNACNAAYTTYGCNACNGARMGNTGGATHGARTAYGGNAARMGNTGY YTNCARTGYGTNTGYMGNMGNGAYGGNGTNAARATHAGYATGGAYATHTTYGTNCARYTN TAYCARCCNGAYMGNTAYGAYAGYTGGAARGAYGGNACNGAYATHGCNCCNCAYCCNGAR GGNCAYMGNGAYGCNAGYMGNCCNYTNGGNGGNMGNGCNGGNAARAARAARATHGARGCN AAYAGYTCNGGNACNGCNCAYTCNMGNMGNCAYCCNYTNAARGARGARTTYACNTCNAAY ACNACNGAYAAYGCNAAYCARGGNAARGARAARGCNCCNAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TTYATGGGNTGYYTNATHTAY TGYYTNATGGGNACNTCNAARGAYATHACNYTNGGNCCNACNGCNATHATGTCNYTNATG ACNGCNACNTTYGCNGAYGCNACNACN---------------------GCNATHGTNYTN ACNYTNGTNTGYGGNYTNGTNCARYTNGTNATGGGNATHYTNAARYTNGGNATHYTNGTN AGYTAYATHTCNTAYCCNGTNATHAAYGCNTTYACNTCNGCNGCNGCNATHACNATHGCN TTYGGNCARGTNAARAAYATHYTNGGNYTNAARGAYATHTCNMGNGARTTYYTNCAYACN GTNTAYGARACN---------------------ATGCCNAGYCCNGAYGTNCARMGNYTN YTNGAYGGNCAYMGNTCNYTNACNTAYAAYGARCARACNAAYAARGTNAARTGYAGYYTN ACNAGYCAYGARATGCCNGCNGARGTNAARGCNATHGARAGYTAYYTNAAYGGNAARAAR TAYAARMGNYTNGCNGAYYTNGAYGCNTTYTCNTTYGARGAYCAYAARACNCAYATHGTN CCNAAYAGYAARAARGAR------AAYGARATGTTYTGYMGNYTNACNYTNMGNCAYYTN GARAARACNCCNCARGCNATHCARMGNCAYATHGAYGGNAARAARTAYAARAAYTCNYTN GCNMGNTGGAARGARTGYCARAARACNGGNGCNAARTTYACNCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNYTNTCNGCNTTYMGNAAYATGCAYMGNGCNMGNMGN GARGTNTTYAAYGGNGAYGARMGNGCNYTNATHGARGTNMGNAAYAARATHAAYTCNGAR TTYMGNGARAARYTNGGNGARACNGAYCCNGCNAARATHGAYGARYTNYTNGTNYTNGCN AARGAYGTNGCNTAYYTNYTNMGNGTNAGYGTNGTNCARYTNCARCARAAR------GAY CCNGARACNTTYGCNYTNMGNATHACNAARGAYACNCAYYTNCCNAARAAYACNCCNTAY GAYCCNACNATGGARATHCCNGCNMGNCCNMGNAARAARAARTGYACNGARAAYGTNGAR TCNTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHATHAAYATHGARCCNAGYCAYTCNYTNTGGAARMGNGAR MGNTGYYTNCAYCAYGGNGGNGCNGTNMGNGGNTAYATGAARGAYCCNMGNGAYAAYGGN ATHCCNMGNGGNCCNGAYGCNGAYCCNTTYYTNTGYCCNGARTGYGAYGCNACNGAYAGY CARTAYGAYTCNGGNAGYTCNGAYAGYYTNTGYTGGYTNATHTCNCCNCAYGARTCNTTY GGNGGNAAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TGYATGTGYYTNATHCAYTCNGAR ATHATGCCNGTNGTNTTYAARYTNYTNGGNYTNYTNMGNATGYTNATHGARGGNCARGAR CARGCNGCNATHMGNYTNGGNCARGARMGNGCNTTYYTNGAYTGYYTNTGYGARTGGTGY ACNGTNGARGTNCAYGCNGGNGTNAARGGNGARGCNCCNMGNGTNATHGCNTCNYTNATH AARAAYAGYMGNTCNYTNGCNGTNATHCARAAYYTNATHMGNGCNAAYTGYATGGGNCCN YTNGTNGCNATGACNACNGCNGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNGARAARGGNACNGCNCAYAARGARTTYYTNMGNYTNMGNTTY ACNYTNACNATHTCNTGYAAYGGNATHGCNAARGAYYTNATGYTNYTNTCNYTNCCNTTY YTNGTNMGNAARAGYTCNTGYCARATHTAYCCNTTYGCNACNTCNYTNATGTGGTAYATH CAYAGYACNAGYAAYCCNTAYGARGAYTTYACNGTNYTNGARAARYTNTCNGTNTCNAAR GTNATGGAYATGATGAARGCNMGNATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TCNGCNYTNACNYTNYTNGAYMGNGCN GTNGGNGAYGARATHAAYMGNTTYGCNCARCCNAARGAYGARYTNGTNTTYYTNACNAAY CARGTNAARATGGTNATHMGNGAYATHMGNGAYMGNATHAAYACNYTNGAYYTNTCNAAR ATHAARGAYAARATGACNATHATGACNGTNAARTGGATGACNATGTCNGCNCCNCARACN AARAGYGTNCAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TTYGARGARTTYAARAGYGAYMGNGGNAGYGARATHAAYMGNGTN YTNATHGARAAYAARGARTAYYTNTCNACNGCNAARAARACNTAYTCNGARYTNGCNAAR CARATGAAYACNTTYAARYTNAGYATHGAYAAYTCNMGNAAYCAYYTNGAYAAYYTNAAR GCNCARMGNGARGCNGARGGNCCNATHYTNAAYGARGAYGGNGAYATHGTNATHAGYGAR GAYGARTTYCARGARATH------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AAYGGNAAYGGN TCNGGNCARAAYMGNTGYATGTCNATHTTYYTNMGNATHATHMGNGGNAARAAYGAYGAR CARYTNAGYTGGCCNGCNTTYGTNTCNACNMGNTTYAGYYTNGTNAAYCARGGNGAYGAY AAYCARGCNAGYYTNTCNAAYGAYAGYGARGTN------ATGTTYMGNTAYMGNAARCCN ATGAGYGAYTCNAARTCNGGNGGNGAYTCNTGGGGNYTNGTNGARTTYGTNCCNCAYTCN ATHATHYTNACNAARAAYTAYATHAARAARAAYTCNATHAARATHMGNGTNGARATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHCARMGNGAYGTNYTNGARCARATHAAYCCNCCNGCNAGY YTNATGYTNYTNGCNGAYCCNACNGARACNGTNAARGGNATGGGNATHACNYTNAARGGN TCNGTNGARAAYGGNTGYGTNGAYGCNGAYGGNAARGTNTAYGAYTTYGTNTCNMGNTAY TTYGCNCCNTGGATGGGNATHCCNGARGAYCCNGTNACNGGNTCNTGGCAYACNGTNGCN GGNGCNTAYTGGTCNAARCARYTNGGNAARAAYCARYTNTAYACNMGNTCNTGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GGNTAYTTYAAYAARAARATHAGYATHYTNGTNATG AAYYTNYTNGARCAYGGNTCNYTNYTNAAYYTNGTNAAYYTNTAYAARAGYAAYCCNAAR YTNATGGGNGGNATHGARCCNTTYGCNTGYTTYGTNACNGTNGARYTNYTNCAYYTNTTY GARCARYTNCAYMGNTGYGARATHGTNCAYGGNGAYGTNAARCCNGAYAAYTTYYTNYTN ATGGAYYTNCCNGTNGTNTGYAAYAGYAAYGAYCCNAGYAARGTNTAYGGNTCNCARYTN MGNTCNYTNTGYYTNACNGAYTTYGGNCARACNATHGAYATGMGNYTNTTYCCNAARGGN ACNGCNTTYAARACNAARGTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CARGAYYTNACNCCN TAYTTYACNTCNGTNAAYAARTTYATHCAYAARGCNMGNYTNGARGGNGGNTCNGTNYTN GTNCAYTGYYTNGCNGGNGTNTCNMGNAGYGTNACNGTNACNGCNGCNTAYATHATGTCN GTNACNGARYTNGGNTGGMGNGAYTCNYTNAAYGCNATHMGNGGNGCNMGNAGYGTNGCN AAYCCNAAYTTYGGNTTYCARAARCARYTNCARAAYTTYGAYAGYGARCAYGTNGARGAR GARMGNAARMGNATGMGNMGNATGTTYCCNGAYAAYCCNTTYCCNGAYGARGARGARTGY MGNTAYAAYATGCAYTGYTAYMGNCARTTYATHYTNACNGGNAGYACNCCNACNMGNTCN AAYGAYYTNTAYCCNYTNCCNTAYAARGCNTAYCARAGY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ACNGAYCCNTTYAGYATGTCNTAYYTNAAYGAR TTYYTNGAYACNGAYTAYGGNGGNACNCAYAAYGGNATHCCNGAYTTYACNGCNGGNYTN MGNMGNGARYTNMGNCARGGNAARAAYMGNGGNCARMGNGGNAAYGTNMGNACNMGNTCN AAYCARTCNAAYGCNCARGGNMGNAGYAAYAARTCNAAYACNAAYGCNGARMGNGARMGN AAYAAYGTNCCNGAYGAYTGGATHTCNCCNGAYYTNGAYTAYCARACNATGYTNGCNYTN CARYTNTCNCAYGARYTNGAYAAYCARGAYGGNAARGCNGARCAYGTNGGNATHGARGAR GTNGCNAARGCNAARTGGATHTGYYTNAAYAARATHTCNTAYAARGAYCCNAARGGNTGY YTNMGNGTNTGGGARGGNGTNTCNMGNACNACNAARAGYGCNGGNGARGCNGAYGCNGTN GGNATGATHGCNATHTTYAAYGAYCCNGTNACNGAYYTNMGNAGYGTNATHATGATHMGN CARTAYMGNCCNCCNATGCARACNTAYACNATHGARTTYCCNGCNGGNYTNATHGAYGCN AARGARTCNGCNAGYCARGCNGCNGTNMGNGARATGAARGARGARACNGGNTAYGAYGTN ACNGTNGTNGAYGTNTCNCCNGCNACNTCNYTNGAYCCNGGNGTNGGNAAYACNACNYTN AARATHGTNACNTGYAARGTNGAYGTNTCNAGYYTNAGY---AARGARMGNCCNAARCCN ACNGGNGGNGAYGCNGAYGARTTYGTNGARGTNGTNGTNGTNCCNATGAAYAAYYTNATG GARAARYTNAARGARTTYGGNAGYCARGGNAAYTGYATHGAYTCNMGNGTNTAYACNTGG GCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARGTN ---AGYTCNGCNGTNATHATHAARCCNCCNCARATHATHGTNCCNCCNCAYGTNGTNGCN ATGAAYCARCCNCARYTNTAYAGYACNGTNCCNATH---AGYTCNCARGCNGTNTCNGCN TCNTCNTCNGCNGTNCCNGTNGCNCCNCCNGCNYTNCCNGARACNGARGCNGGNGCNGAY AARGGNGCNAARAARAARAARAARGAYAAR------------TCNGGNGGNGGNGCNACN TCNAGYYTNATGATGAARAARAARMGNGTNTCNTCNATGGTNCARAARTGGCARCARGTN AARATGGARGTNGARAARGARGAYMGNGCNAARGARYTNMGNCARGCNGCNATHMGNGAR AARATHAAYCARYTNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GGNACNMGNTTYYTNAARMGNGGNACNAAYYTNGAR GGNTTYGTNGCNAAYGARATHGARACNGARCARATHGTNCARGAYACNACNGTNACNTGY YTNGAYMGNGGNAARGTNTCNTCNTTYGTNCARYTNMGNGGNTCNGTNCCNYTNTTYTGG TCNCARGAYATHTCNAARATGGTNCCNAARCCNCCNATHTCNYTNGAYCARMGNGAYCCN TAYTGYAGYGCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CARCARCARGARAARGARAAYGTNAARAARTCNGARAAR GCNAARGCNCARAAYCARCARTCNGCNAARYTNAGYYTNGCNAGYGTNGGNAGYTGGACN GGNACNGGNGGNACNAAYTCNACNTGGGARGCNCCNGCNCCNGCNCCNGCNACNGCNCCN GTNTCNTCNGGNGGNATHTGGGAYATGGGNYTNCCNCARTCNAARGCNGCNGGNAARACN GGNAAY------------------------AGYATHGTNGTNCCNCAYACNCARAAYCAR CARCARCARTCNAARAARAAYACNGCNAARAGYAAYAARGCNGCNGCNCCNGCNAARCAR AARGARGTNGARACNGTNCARAARYTNTTYCARAAYAARAARAARGAYAARTTYTCNGAY TGGGTNACNGAYAARYTNTCNCARTTYTCNTCNGAYATHGAYATHCCNACNTTYGTNTCN TTYATHGTNGARGTNGAYAGYCCNGAYGAYGTNTTYGAYTAYGTNAARACNTAYYTNGGN GAYACNAARGARACNCARGARTTYTCNMGNCARTTYYTNGARMGNMGNAAYCARCAYAAR AAYCARATGMGNYTNCARAARCARYTNGARGARGAYAGYATHTGGGGNCCNGCNCCNGCN ATHAAYCCNMGNACNGCNACNGAYGGNTCN---------------GGNATHTCNGAYGGN GGNAARGCNAARAAYAARAARAARAARAARGCNCARAARYTNGAYGGNAGYATHYTNGGN TTYACNGTNCAYGCNGAYTCNAAYMGNAARAAYACNGGNGARTTYGARACN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AGYCCNMGN MGNCARTGGAAYGCNCCNTCNGAYYTNAARYTNACNCCNMGNGGNGTNYTNGAYACNGAY GCNYTNATHCARCARGTNGARAARGARAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GCNACNGARYTNTGY AAYAARGCNAAYGARGARTTYGTNGARGARAAYTAYCARMGNGCNGTNGAYYTNTAYACN GARGCNYTNGARYTNGAYGGNAARMGNGAYGAYATHTTYTGYTTYMGNGCNCARGCNCAY YTNTCNYTNGGNGAYTCNACNGCNGCNATGAARGAYTAYAAYGARGCNATHAARYTNAAY AGYAGYAAYCAYAARGCNTAYGTNAARAARGGNTCNYTNYTNYTNAARATGGAYGAYGTN YTNCARGCNCARAAYGTNTTYAARGARGGNCARAARAAYTGYGARAAYAAYCARGAYTTY GGNGAYTGGYTNAAYAARGTNGARAGYMGNATG------AARGARYTNGGNATHGTNTCN CCNGARYTN---------------------------------CCNACNAAYATHAARCAY AAYTGGTAYCARACNCAYACNCAYATHGTNYTNACNYTNYTNGTNAARAAYGTNAARAAR GARGARYTNACNYTNGAYGTNGAR---MGNAARTCNGTNAARATHGTNGTNAAYMGNGAY GARCARAARTGYGAYYTNAAYATHACNYTNGCNCAYCCNATHGTNCCNGARCARACNCAR TCNAARYTNTTYTCNTCNAARATHGARATHAARYTNAARAARCAYGARGGNATHCARTGG GCNAARYTNGARGGNTCNCCNGAYGARGARCAR---CCNGTNYTNCCNCCNTGYGCNGCN CCNATH---GCNGCNGARCCNCCNMGNTAYCCNAGYTCNTCNCAYCAYACNMGNGAYTGG GAYAARYTNGCNGCNGARGTNACNGARGARGARAARAAYGARAARYTNGARGGNGAYGCN GCNYTNAAYCARTTYTTYCARAARATHTAYGCNGAYGCNTCNGAYGAYACNAARAARGCN ATGATGAARTCNTTYAGYGARTCNGGNGGNACNGTNYTNAGYACNAAYTGGTCNGARGTN GGNGCNAARAARACNGARGTNAARCCNCCNGAYGGNATGGARTAYAARAARTGGGAR--- ------------------------------------------------------------ ------------GCNGCNGCNCCNGTNGCNGCNCCNTCNCCNAARAARGCNGCNAARACN GARGARAARAARGGNMGNGGNMGNCCNCCNYTNTCNGCNGARGARAARGCNAARMGNATH GCNACNAARAARGCNTCNTCNGGNMGNGGNMGNGGNMGNCCNAARGGNTCNACNAARAAR GCNCCNGGNAARAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNGARMGNYTNTAYTAYTGGGCNGARTTYGCNGCNGARCCNYTN AARTCNTAYGCNACNGGNYTNYTNAGYGGNGCNATGGARYTNAAYGAYATGGCNGTNAAR TTYMGNGAYGARAGYATHCAYATGGTNCCNATHATGATHGAYMGNYTNCAYGCNYTNATG ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GCNAARTTYGTNAGYAARTGYTTYAAYCAYACNGCNTTYGTNCARGCNAAY TTYMGNAAYAARAARCARYTNGARAARGAYGTNGAYAARYTNTCNGCNYTNGGNCARGCN GAYTTYAGYGTNGCNYTNMGNTTYGARAARTTYAARGARTTYTCNAAYAAYGAYACNAAY GAYGARAAYAAYATH--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYGARGAYMGNGTNAAR YTNGAYGAYYTNATGGCNGCNAGYACNACNATHAGYTTYGGNTCNAARAARATGAARGTN TCNGAYGARGAYGTNAARAGYAARGCNGAYAARMGNAARGCNATGACNYTNTCNYTNYTN CARCCNGAYYTNGTNCARTCNGAYCCNAARAARGAYGAYMGNGAYACNGCNTTYGCNCAR CARTAYTTYAAYCARGTNAARCARACNYTNTCNTCNGAYCCNGARMGNTTYTAYAARTTY YTNTCNYTNYTNAARGAYYTNAAYAARGAYCAYACNAAYCCNGTNGARYTNTAYYTNGAY ATGGTNTCNYTNYTNTCNGAYCAYCARCARYTNGTNGARGAYTTYGCNGGNTTYYTNYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNAGYCCN CCNYTNAAYTCNACNGAYGAYMGNGCNATHMGNACNMGNAAYMGNGTNMGNAARAARCCN CARCARMGNMGNGTNAAYGGNAAYGAYAAYTAYTAYCCNCCNCCNMGNTTYCARGGNGTN MGNMGNCCNMGNAAYGGNATHAAYGGNGARGTNAGYATGCAYGGNGGNCCNATGTAYCCN GGNGAYCARGARAAYGGNCCNATGGAYGCNGTNGARGARAAY------YTNYTNCARTGY YTNTCNGCNATHCCNGARCCNAARGTNATGGAYGTNGAYGCNMGNATHGCNAARATHAAR YTNTCNCCN--------------------------------------------------- ------------------------------------------------ATGGARCAYCAY GARYTNGTNCARGARATGGCNTCNATHGARMGNATGGTNACNCARGAYMGNYTNAARCAY GCNMGNAARMGNMGNYTNCARCARATGAARAARTGGGGNCARTAYGARAARTCNYTNGAR AARGARAGYACNAARAARAARMGNAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AARYTN GAYAARTCNAARATGGARGCNTAYATHAARAARGCNGCNAARATHGCNGCNGARTAYAAY GCNGGNYTNATGMGNGARAARMGNGARGARMGNCARGCNTAYTTYGAYYTNCARACNTAY ACNATHCAYCAYACNAARCAYMGNTAYMGNACNYTNCCNCCNGARATGACNAARATGGGN TCNTAYCCNGTNTCNYTNATHGCNGGNCARTAYCARGAYAARTTYAARMGNTAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNATGGCNAARMGNGGNCCNCARTCNGARYTNACNGAYMGNAAYTGGGAYCARGAR GARGARCCNGARGARGCNGGNACNTTYAARCARGCNTCNAARGAYATHATHGGNCARMGN YTNATHAARAARGCNAARMGNMGNGGNCARGARGAYGARGARGGNAARACNGTNGCNTTY GGNGGNTTYCARGGNYTNATGGCNMGNCCNTCNATGGGNCARAAYAAYAAYGTNGAYAAR CCNAGYATGACNACNGGNAAYGAYTCNGCNTTYAARCCNAAYTTYACNGGNGGNGCNACN TCN------CCNGCNGAYAAYAGYGAYGCNTCNTCNAARCCNGAYTCNAARGAYAAYTCN TCNTAYYTNCAYGGNYTNAARGCNYTNAAYGARAGYGTNYTNGCNTGGATHAARCARCAY GTNGAYAARAAYCCNTAYATHATHYTNACNCCNATHTTYAARGAYTAYGARAARTAYYTN GCNACNATHGARCCNAARAARGGNAARGCNAAYGGNTCNTCNGCNGAYTCNAARAARGAR AARAARGAYAGYGARGARAGYACNAGYACNTCNAARGCNCCNTCNTCNTTYTCNTTYGGN ---------TCNTCNTCNTCNAAYGGNGAR---------GGNTTYAARCCNGCNACNACN ---------GGNTTYACNTTYGGNAARACNTCNACNGCNTCNCCN------GGNTTYTCN TTYGGNYTNAGYAAYAAYTCNTCNACNGCNGCNGCNGCNACNACN---------ACNACN ACNGCNTCNGGNGGNGGNTTYGTNTTYGGNGGNAARAGYGTNGGNGGNGCNACNTCNACN GCNCCNTCNACNGGN---TTYACNTTYGGNAGYAGY------------GGNAGYACNACN ACNGCNGCNCCNTTYGGNAGYTCNGGNTTYTCNTTYGGNTCNYTNGCNTCNAARGCNATG TCNCARAAYTCNGCNGGNAAYTCNCAR---AGYCARGARGGNGGNGAYGAYGAYGARTAY GTNCCNCCNAARCCNGARGTNAARGARATHACNGARGARGGNTCNATGTAYTCNAARMGN TGYAARYTNTTYTAYCARAARGARGGNCARTGGACNGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARGCNGTNMGNGARACNGCNAAYMGNTAYACNCARATHATHGTNACNGCNCARCAR GCNGARYTNYTNAARMGNGARGAYCARTTYYTNTAYATHTGGGGNACNTGYGGNTCNGGN AARACNYTNATHYTNACNYTNAARGCNMGNCARTGGYTNMGNMGNAARCAYAARGTNATH ATHYTNAAYACNMGNACNTAYTGGATGTTYGGNTAYTCNTAYAGYTGYGAYTCNMGNGTN GTNTGGACNGCNMGNGGNGCNYTNATHACNTCNTGGATHGTNTTYATHATGTTYTTYATH TTYYTNGCNATHTTYGAYCCNYTNGGNGCNYTNAARGAYMGNAARAAYGTNCARYTNTCN ACNAGYAARMGNGGNGAYGAYCARGTNGTNATHGCNAAYGCNTCNGCNACNAARATHTGG GARAGYMGNTGYMGNYTNYTNTGYTGYTGYATH--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNTCNCCNTTYACNCCNATGCCNTCNTAYGAYAAY ATGAAYACNCCNGAYYTNAARAARGARATHGGNMGNATHGGNGTNMGNCCNATGTGYAAR AARMGNATGAARAARYTNYTNATHGAYGTNTAYCARAARACNCAYCARTAYGARACNGAY TCNGAYATHGAYGTNACNCCNGTNAARTCNACNCAR------------------------ ------------------GGNGARTCNYTNCARATGAARGTNYTNAARAARTCNACNACN TGGCAYGARGARGARACN------------------------------------------ ------------------------------------MGNAGYTCNGGNAGYTGYTCNGAY YTNCCNTCNGCNAGYGARGCNGAYATHGAYAAYMGNAARAAYGCNAARMGNMGNGCNGAY AARGGNGCNGTNACNAARTCNYTNAARCCNAAYACNGGNAGYGGNACNAGYTGYGAYGAR AARGAY---GGNGARGARGARGAYTGGATHTCNAGYTCNCARGARTCNAAYTAYAGYGAY GGNCCNGGNGTNCCNGARGARAGYATHYTNCARGARYTNCCNCCNGARGAY------GAY GAYACNCCNACNCARYTNACNCARACNAGYYTNGARGCNYTNAARGAYMGNYTNACNGCN TTYATHMGNGAYMGNCCNGARATHTAYAAYAARGTNYTNATGTAYGARGCNYTNGARYTN GAYGTNYTNAARAARMGNATHTCNGARGCNGGNATHMGNATHGGNATGGCNMGNYTNCAR GAYTTYYTNGAYGARAARTGYATHACNTTYTCNATGAARAAYATGAGYAAYMGNAAYAAY MGNCARATGCARAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG GGNMGNAARAARATHCARATHGCNMGNATHAAYGAYGARMGNAAYMGNCARGTNACNTTY ACNAARMGNAARTTYGGNYTNATGAARAARGCNTAYGARYTNAGYGTNYTNTGYGAYTGY GARATHGCNYTNATHATHTTYACNAGYAAYAAYAARYTNTAYCARTAYGCNAGYTCNGAY ATGGAYAARGTNYTNYTNAARTAYACNGARTAYAAYGAYTCNGTNGTNAGYCARACNAAY AARGAYATHATGGAYATGYTNAGYAARAARGAYAGYAARGGNGGNGAYYTNGAYGGNGAY GAYGAYGAYTTYCCNATHTCNCCNMGNACNGAYGARAGYTAYMGNAARATHGAYGCNGAR TTYGCNMGNGCNATGAAYGAYGGNGGNYTNAARACN---TCNGTNCARTAYCARATHCCN GTNCARGCN---ACNGCNCARTAYACNGCNGCNCCNGCNAGYATGGCNAGYGGNGGNTCN GTNATHGTNYTNCARCCNTCNGGNCAYGTNGCNAAYACNGTNGCNMGNCARCCNGCNGCN ---GTNAGYMGNGTNAAYGCNTCNCCNAGY---ATGACNACNCARAARGTNACNACNACN AAYGCNTCNAGYAGYCCNCAYCCNGTNGCNYTNCAYATGTCNGGNGAYATHCCNMGN--- GTNATHGCNGCNTCNACNTCN---------------CARTCNACNGCNACNAARAARCCN GGNYTNAARGTNGTNATHCCNGAYMGNGGNCCNACNGTNTCNCARGGNAARGTNCARCCN GGNACNTCNYTNGAYACNCCNACNGTNTCNATHGCNACNCCNAAYAGYCARAAYGCNGCN CARGGNGCNATHCARGCNATHYTNCARTCNGGNGAYYTNYTNACNAGYGCNGAYATHCCN GGNYTNTCNCCNYTNGTNTAYCARYTNAAYAAYCARGGNCARGGNCCNGGNCCNYTNACN GCNGCNYTNCARGCNTCNGGNGTNTTYACNCCNGGNGGNTCNYTNTCNATHTCNTCNACN CCN------------ATHATHYTNCCNGCNCARAARACNGARYTNGTNAARCARGAR--- CCNGGNTCNCCNCAYAARYTNGAYCAYTCNGCNGARAARYTNTCNACNACN--------- ------------GGNGARCCNCCNGARAARMGNTCNMGNTTYGAYACNGAY--------- ------------------------------------------------------GGNAGY GGNGGNGGNGGNGGNATGACNMGNCCNATGGGNAAYCCN------------------GGN TTYACNGGNCARAARTGYTAYAARTGYAGYMGNGTNGGNCAYTTYGCNMGNGARTGYCCN CARGAYCARGARMGNTGYTAYAARTGYAAYGARTTYGGNCAYATHGCNAARGAYTGYGAR AARCCNATH---ACNGCNGGNGCNTGYTAYAAYTGYGGNAGYAGYGAYCAYYTNCARMGN GAYTGYCCNCARGCNATHGTNAARTCNTGYTAYCARTGYGGNCARTCNGGNCAYYTNGCN AARGARTGYTCNCCNGGNCAYGGN------------CAR---GCNTTYATGGAYGAYMGN AARTGYTAYGCNTGYGGNGGNGTNGGNCAYYTNGCNAARGARTGYCCNTCNGCN------ ------MGNAARCARTGYTAYMGNTGYCAYGARGCNGGNCAYYTNCARAARGAYTGYCCN TAYGGN---AGYMGNGAYCARCARTGYTAYAARTGYGARGARGTNGGNCAYGTNGCNMGN GAYTGYCARGCNGARTAYCARMGNGCNGGNCCNAAYGARAARAGYGARAARYTNCARGAR ACNAARAAYTAYACNACNCAYTCNYTNGCNAGYGTNGCNTAYCARATHAAYAAYYTNGCN ACNAAYTTYYTNAARYTNYTNGAYYTNCARCARAGYCARYTNACNGAYATGGARTCNAGY GTNAAYCAYYTNAAYCARATHGTNATGATHCAYAARGARAARGTNGCNMGNMGNGARATH GGNGARYTNACNTCNAGYMGNAAYGTNCCNMGNCCNATHGGNATGAARAAYGGNATHATH TAYCCNGAYCARMGNGARMGNCCNATHAARTAYACNMGNAARCARATHGAYTAYTCNGTN YTNGAYGAYATHGGNCAYGGNATHMGNACNAAYAAYCARCARCARGGNACN------ACN ACNMGNTCNCCNTCNATHAGYAGYACNCAYAGYAAYAGYAAYGCNAAYAAYAAYCARGCN CCNACNTCNAARCCNCCNACNCCNCCNATHGGNAGYGGNGGNAGYACNGGNACNATHGGN MGNTCNGCNGGNGGNCAYTAYMGNTCNYTNGGNCCNCCNGTNGCNCCNCCNGTNGCNCCN AAYTCNGTNTCNCCNTTYCARCARCCNGTNCAYCCNMGNATH------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AARMGNTGYYTNATHGTNACN GCNGAYGAYTTYGGNTTYAGYACNGARMGNAAYMGNGGNGTNATHGARGCNTTYCARAAY TCNGCNGTNAARAGYGCNTCNYTNYTNYTNAAYTGYACNGGNACNTTYGARGCNGCNCAR TTYYTNAARAAYAAYAARYTNTGYCCNGGNYTNCAYTTYAAYYTNACNGARGGNCAYTCN YTNAGYCAYAARAARCAYTCNACNYTNACNGAYACNTCNGGNACNTTYTGGGGNAARTTY GGNYTNMGNAARMGNYTNGCNGAYGGNAARATHGAYYTNAAYGARATHCARGAYGARATH CARAGYCARATHGAYTAYTTYAARGAYATHGTNGGNGARAARCCNGTNTAYGTNGAYGGN CAYCARCAYATHCAYGTNCAYCCNGAYGTNGCNAAYATHTTYGCNGCNACNYTNAARGAR AAYGGNATHAGYGTNACNMGNYTNCCNAAYGARYTNTCNATGGARGCNAARGGNTGGGTN ACNGGNCCNTGYATGGAYTTYTAYACNGARGTNATGGAYAAYGCNMGNATGTGYGCNGAR MGNTTYAAYGCNTGYGGNATGMGNTTYACNGARMGNTTYGTNGGNYTNTCNACNATGGGN MGNGAYATGACNYTNCAYMGNYTNCARTCNAGYATHYTNGARGCNTTYAARCAYGCNGAR ACNCAYGAYGAYMGNAGYAAYMGNGGNTCNGTNACNTGYGARYTNATGACNCAYCCNGGN TAYCCNACNGGNAARAAYACNGGNGGNTTYGAYGGNGTNTCNGAYGARTTYGGNTGYTCN AARGAYMGNCARCAYGARATHGTNACNYTNAGYTGYGARGARATGATGGAYTTYTAYMGN CARCAYMGNATHGTNYTNGARTCNCAYMGNATHYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CARCAYATGCCNMGNYTNGGNAARCCNTCNYTNGTNTCN CARACNACNCAYYTNGGNGARMGNGCNTCNAGYGCNGTNGAYAGYTTYATHCARGARGGN ACNGARTAYAARGARGARGAYAARCCNCCNYTNGARCCNCCNATGTCNGAYGARGTNATH CCNCCNAARGCNAAYGAYACNYTNGTNTCNGTNGAYGCNYTNTTYAARGTNYTNCAYCAY GGNGARATHTCNAARGGNGAYAGYCAYMGNTTYAGYGTNACNGCNGAYCCNGARGARCAR ACNTCNTAYGARMGNYTNAAYGCNGTNTTYCARGARYTNAAYGARGAYGAYAGYTCNTCN CCNATHCARTAYAARATHYTNATHGAYCAYCCNYTNATHCARGAYGTNGTNGTNGCNTGY AARCAYTTYAARGCNYTNGAYATHAARAGYTTYYTNGCNGGNTCNTCNCAYGAYATHGCN GARATHACNAGYYTNAARACNATGGAY---------TTYCARACNTTYGCNGAYYTNAAR GGNGCNGTNAARGAYYTNGARCARGCNACNCARTCNGCNTTYGTNATHGAYGAYTGYGTN AARACNAARATH---CCNTTYYTNAARGARACNCAYATHTAYGAYMGNGTNATGTTYTCN TGYAARCARGGNMGNACNMGNAARCCN---CARGGNMGNGGNATHMGNCARCAYAARCAR TCNATHAARGTNGGNTGYTGYGCNAARATHMGNGCNGTNYTNAARGARAARGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNGCNGTNGTNGCNMGN MGNYTNCARCCNYTNGCNYTNGGNYTNTTYMGNAARGCNGGNAARTCNYTNCAYACNACN TCNMGNAARACNGGNGGNGARACNYTNTAYMGNGARAARATHTAYGARTAY------AAR GARCCNAARTAYATHCARTAYGGNGGNACNGTNTTYAGYGCNTTYYTNTGGTAYTGGATH YTNTAYCAYTGYTAYTTYGARTTYGGNCAYYTNGTN------------------------ ------------------AARATGCCNTGYGARGAR------ACNTTYYTNAAYAARYTN GGNGARATHCCNYTNATHAAYGAYGGNTGGTCNACNGCNACNGARTAYTAYTCNMGNATH AARGAYTAYAAYTCNGTNATGMGNYTNACNYTNTCNATGGCNGARTCNAGYGTNAARGTN GCNGGNACNGTNTCNACNCCNGTNTTYAAYYTNTAYCARCCNCARATHAAYAAYATHAAY GGNTAYGCNTGYAARAARYTNGAYGARYTNGARAAYMGNTAYCCNTCNATHAARCARCCN ACNGARGARTGGAARAARACNTGYACNGGNYTNGTNGARCCNGTNGTNGGNCARGTNAAR CCNYTNGTNAGYCAYGTNCAYGAYATHGTNAAYAAYGGNAARCARAARATHGTNAAYATH AARACNGCNGGNACNAAYATGGTNGARGARGCNAARAAYYTNGGNGTNGGNACNGCNGCN CAYGTNTTYAAYTCNACNTTYGARACNACNCCNGGNMGNTTYATHACNMGNACNGTNGAY AGYGCNYTNAAYGTNGCNGAYGGNYTNGTNGAYAARTAY---------YTNGTNGARGAR GARATHGARCCNATHGAYGAYAAYGAYACNTCNGAYGAYGARYTNAGYTCNAGYGAYGAR AGYACNGARAARAAYATGGARCARATGCARGARATGGAYCCNACNCCNMGNMGNGTNATG ATGCAYGCNGGNAGYATHTCNGARAARATHMGNMGNMGNATGTTYAARAARGCNATGAAR GAYTTYACNTAYGCNAARGCNMGNGCNTCNTCNGCNYTNAAYCAYATGCARAGYACNGTN AAYYTNGTNGAYTTYGCNAARAAYAAYATHACNACNGTNAARGGNAARGCNGAYGAYYTN TGGATHGARATHACNAARGAYYTNGAY---------CCNTCNGARCARGARAARACNACN AAYGCNGGNACNYTNGARGAYMGNGTNATHGCNYTNGGNMGNYTNGTNACNMGNCAYGTN MGNTCNAAYGTNACNGCNTTYGARAARGTNTTYTCNGARGTNGGNGARTTYGGNMGNCAY CCNATHTCNAARTCNAARGARTAYAARCARYTNATHGARACNTTYGTNTCNATHGARTCN ATHCARACNTTYTCNTCNGARAARYTNGCNCARGCNAAYGCNTCNYTNAARTCNATHCAR AGYATGATHCARACNATGGTNAAYTCNGTNAARGAYATGAAYTGGATGGTNYTNGAYATH GAYATGAAYGARATHCCNYTNAGYGAYAGYGAYYTN------AARATHGGNYTNAAYTCN MGNCARGTNTTYTGYYTNAARCARTCNTGGAARGGNATHAARMGNAARATGGARGARACN GGNGTNGARATGTTYGTNMGNYTNTTYAARACNAAYCARGAYYTNCARTCNATGTTYCAR GGNTTYAARGAYATHMGNTCNGAYGAYGARYTNMGNTCNAAYGARGCNYTNGARTAYCAY GCNTCNYTNGTNATGTCNACNYTNGAYGAYGCNATHACNCAYATHGAYAAYTAYAAYTTY GTNCAYGARYTNYTNGCNAARACNGGNGCNTCNCAYAARMGNTTYGAYGGNTTYGARCCN AARATHTTYYTNAAYATHAARCARCCNTTYYTNGAYGCNGTNAARGTNACNYTNGGNGAY MGNTAYACNGARAAYATGCARAAYATHTAYACNATHGCNATHAAYTTYYTNGTNGAYACN ATGGTNGAYGGNYTNGARCARGCNYTN--------------------------------- ------------------------------------------------------------ ---------------------------------------------------CAYGGNACN YTNYTNCCNYTNCARTAYGCNTGYTGYGTNGGNGAYCAYCAYGCNYTNCARYTNYTNATH GGNCARGGNGCNAARGTNAAYGARCCNGAYGGNTAYAAYMGNACNGCNYTNTAYTAYGCN GCNGARCARGAYGARMGNTGYGTNMGNATHYTNYTNGARCAYGARGCNYTNCCNGAYATH GGNGAYGGNAAYGGNGAYACNGCNYTNCAYTGGGCNGCNTAYAARAAYAAYACNYTNTGY GTNTCNCAYYTNYTNMGNCAYGGNGCNAAYGTNAAYGCNGCNGAYYTNAAYCARGARACN TCNYTNATHTGGGCNGCNMGNAARGGNAAYATHGARGTNGTNMGNATHYTNYTNGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARACNGCNTTYGTN ACNGGNGGNGCNCARGGNYTNGGNCAYGCNTAYGTNCARAARTTYYTNGAYGARGGNTCN AAYGTNTTYTTYGGNGAYATHAAYGGNGAYYTNGGNMGNTCNGTNGARCARGCNTTYAAR ACNAARTAYGGNCARGAYMGNGTNGCNTTYGCNCARTTYGAYGTNACNAAYYTNGAYAAR TTYAARGARGCNTTYGGNTCNGCNGTNMGNCAYTTYGGNGCNGTNGAYATHATGGTNAAY AAYGCNGGNATHYTNAAYGARGGNYTNTGGGARAARATGATHGAYATHAAYTAYMGNGCN GCNGTNTAYGGNACNATGYTNGCNATGGARCAYATGMGNAARGAYAARGGNGGNMGNGGN GGNMGNATHATHAAYGTNAGYTCNGTNATHGGNATHGGNAGYCAYCARTCNATGCCNATH TAYTGYGGNACNAARCAYGCNATHMGNGCNTAYTCNACNTGYATHTCNATGACNCCNGGN YTNGARTCNGARATGGGNATHGARATHGCNGTNYTNTGYCCNGAYGCNGCNGAYACNGAR YTNGTNTCNAARATGGAYGARACNMGNGTNATHGGN------------CAYAGYAARATH AARGAYATGYTNGARTCNMGNAARTGYTCNGTNTCNACNATHACNGAYGGNYTNTTYTCN YTNYTNAARMGNGAYGCN---ATHAAYGGNGCNATHYTNYTNGTNGTNAARGARGGNGCN MGNTTYCARGARATGGARMGNAARGAYYTNGGNACNGARTGGCCNGTNCCN------GGN CARGTNTGYACNGARAAYAGYCARTGYCARGCNGGNGARTGYTGYCARATHATGAGYGAR TTYATGGTNGTNAGYAARMGNGAYYTNGAYYTNCCN------CAYATHYTNACNAARCCN GTNMGNACNGGNACNTGYGARGCNTAYAARCCNGARGGNGCNMGNTGYGGNACNTTYGAY AARATGAAYGGNTAYTGYAGYTGYGARCCNGGNACNAGYTGYAARGGNATGCARGTNCCN ACNAGYCCNACNAARMGNATGATGCCNMGNMGNATHATHGCNCCNAARCCNGGNTAYACN TGGGARTTYACNTGYACNMGNGTNGAYTAYGAYAARATGGGNTTYGCNCARAGYCCNTAY TCNGGNATHGAYTAYAGYMGNGTNTAYCARGARGGNTGYTAYGTNYTNGGNCCNCARATG GGNYTNAARYTNTTYCCNGCNACNGCNCAYATGYTNGAYYTNGCNGTNTGGGTNTAYGAY MGNAAYGGNYTNACNATHGGNYTNGAYGTNTAYYTNCARTAYTTYYTNMGNCCNGAYGAR YTNGCNGAYYTNTTYMGNAARTAYCAYGAYGAYTAYGARAAYGTNATHTTYMGNAARGGN GARAGYATHATHAARAAYATGGCNCCNYTNTTYAGYYTNGARCARTAYMGNYTNAAYMGN TCNAGYGTNGARAARGARYTNTTYAGYMGNATGMGNTTYGGNYTNTCNGGNAAYTGYTGY AAYACNMGNTTYCCNYTNCARGCNGAYGTNGCNACN------------------------ TGYATHAARTCNCCNGAYTGYGAYMGNGGNYTNCAYATHGAYGTNGGNTTYTTYCARATG GCNGGNATHAAYATHCCNAGYAAYGTNATGGARMGNTAYATGAARCARTCNYTNYTNCAR YTNGARAAYGARMGNGARATHTTYTTYCARCAYMGNGCNGTNGTNACNAARYTNAAYTCN YTNAARGTNAARGARATHYTNAAYACNGCNMGNGARGTNMGNGARGCNGCNCARGCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GCNTCNYTNGGNGTNGTNGCNGCNATHYTNCCNGGNGCNTCNGCNTTYAGYGARGTN TCNCCNYTNATHGCNTCNGCNACNGTNGCNAGYTTYATGYTNYTNTTYYTNATHGTN--- ATGATHGTNTTYTCNYTNTCNGCNGAYTCNTGGATHMGNTCNTCNATGAARAARMGNGGN AARGTNAARMGNTCNGTNTCNTAYYTNCARAARAARMGNMGNGCNCARGARCARYTNYTN GCNGCNTCNMGNMGNCARTCNGCNCCNAGYACNCARGCNCCNACNATHCCNCCNCARTCN ATHTAYACNGARGCNATGCCNCCNCCNATGACNATGGTNCARGGNTGGAAYACNGARACN CAR---------AARATHTAYGARGARAARGGNTAYGCNYTNGAYYTNGGNGARGARAAY GARACNGARTTYCARATHGARACNACNYTNGTNGAYAAYGARGTNYTNGAYGTNGGNCCN TTYAARAARATG---AGY---ACNGGNGCNGAYGCNGTNGARGGNAAYGTNTAYGCNAAR CCNTAYATHTAYTCNAAYAAYGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATGGCNGCNCARTAYYTNAARATGCARCAYTTYAAR GGNAARGTNTAYYTNGTNGGNMGNGARGARAGYATHGGNAARGARYTNCARGAYGTNGGN ATHTCNTAYACNGGNGTNGGNCCNGAYACNGTNGAYGGNACNGAYATGCCNCARTGGYTN GARACNAARYTNGAYCCNGARGTNAAYTGYGTNYTNACNGGNTTYGAYCCNCAYATHAGY TAYCCNAARATGYTNAARGCNGCNAGYTAYYTNAARAAYCCNGAYTGYYTNTTYATHGCN ACNAAYGARGAYAGYTGYATGCCNAAYAARGGNGARYTNYTNATHCCNGGNACNGGNTGY ATHGTNYTNCCNGTNGCNTAYGCNACNTCNMGNMGNCCNGTNGTNGTNGGNAARCCNGAR ACNACNATGTTYGARGTNYTNMGNGAYYTNCAYGGNYTNGAYCCNGCNMGNTGYYTNATG ACNGGNGAYMGNYTNGAYACNGAYATGYTNTTYGCNAARAAYTGYGGNATGAARTCNYTN ACNGTNYTNACNGGNGTNYTNACNCARGARGARGTNACNGAYGAYAARAAYACNATHATH CCNGAYTTYTAYGCNAAYTGYYTNGGNGARYTNGGNCAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GGNMGNGARAARGAYMGNTCNCAY GGNAAYAAYAAY------MGNAGYGGNCARGAYMGNGAYMGNAAYMGNTCNAGYCAYTGG GAYTCNGAYMGNGAYAARAARMGNCAYGGNGARGAYTAYGAYCCNGCNGARCCNACNGAR GAYGAYGAYGAYGGNGGNAARAARGGNGAYTCN---TCNAAYYTNTAYTGYCAYGTNTGY AGYGTNTCNGTNTAYGAYGARGARAGYTTYCARMGNCAYYTNAAYGGNYTNAARCAYAAR GCNMGNATGGARAGYYTNACNACNGTNCAYCARATGMGNTCNACNCARYTNAARTCNMGN YTNAARGCNGARGARCAYYTNMGNAAYATHGARMGNAARGGNGGNMGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARATHATGAGYATHACN MGNACNYTNGGNGCNGTNTAYGGNACNTGYATGYTNTCNTCNATGYTNMGNGTNCARYTN AAYATHATGGGNGGNTAYYTNTAYYTNGARAGYATHCAYCCNGCNAAYGGN---ACNACN GAYGGNGGNAAYGTNATHMGNATHCCNCARAARGTNCARGARMGNTAYYTNTCNATHGTN AARGARTTYATHGARCARGGNTTYYTNGAYTTYATHCAYGGNYTNAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARTTYATHGARYTN GTNMGNCARAAYMGNTGYYTNTTYGAYTGYTCNCCNCARAAYAARGAYACNGTNYTNAAR AAYAAYATHTGGGCNGARATHGCNCARGARATGGGNGARGARACNATGACNGGNGARGAR TGGAARAARTTYTGGAARCARAARMGNGAYGCNTTYGTNAARAARYTNMGNGARATG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGACNTCNGCNGCNTTY AGYYTNGARAAYCCNGTNTTYCARGCNTTYATHGGNTAYGGNGCNYTNGTNYTNYTNAAR ACNYTNATGYTNGCNYTNYTNACNAGYTTYAAYMGNATHACNAARGGNATHTTYGCNAAY GAYGARGAYGTNTCNGCNTTYGGNAARGARAARTCN---AARATHGTNYTNAAY---AAY ---CCNGAYGTNGARMGNGTNMGNMGNGCNCAYYTNAAYGAYYTNGARAAYATHYTNCCN TTYGTNYTNYTNGGNYTNYTNTAYGTNGGNACNGGNCCNTCNYTNTCNATGGCNYTNATH CAYTTYMGNGTNTTYGCNGCNGCNMGNATHYTNCAYAGYATHGTNTAYGTNTGYAARGTN CCNCARCCNGCNMGNGTNYTNTGYTTYACNGTNGGNATGGTNGTNAAYGTNTCNYTNGCN GTNCARATHATHMGNCARGGNTCNTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNTCNCARCCNYTNAAYYTNTCNGTNATHTGYTCNCARYTNGCNAGYGTNCAY TTYTAYYTNGGNATHGTNGARYTNGGNYTNCAYGARGCNACNAARGTNGAYCCNCARGGN ATGGCNGTNCAYTTYTAYAAYAAYGGNGARCCNCARGARGAYATHCARGGNATGCARCAY TAYATHGCNMGNATGGAYTGYTAYAARTGYGTNACNGAYACNYTNACNTAYYTNTGYGTN GCNAGYTCNAAYCARGCNCARGTNCCNGCNAAYCCNTTYATHTCNACNCCNTCNAARGCN GTNGARACNGAYATHATGGARGCNCARCARGCNGARCARTTYMGNGARGARGTNTTYCAY ACNGCNYTNMGNTCNGAYGAYTCNYTNTTYCAYGCNGCNYTNTAYGARTGGYTNTTYAAY ACNAAYCARGCNGARAARYTNYTNGARATHAAYACNCCNTAYGTNGARCARTAYYTNMGN MGNAARGTNAAYYTNCARACNGARAAYACNAAYGCNYTNGAYATGYTNTGGMGNCAYTAY GARAARGTNGARAAYTTYCCNGCNGCNACNMGNATHYTNTCNCARYTNGCNGARMGNCAY GGNACNAAYGTNAAYYTNACNCARMGNYTNGARTAYYTNTCNMGNGCNGTNGTNTGYGCN AARAGYTCNACNTCNMGNYTNGGNACNTCNGCNGGNGGNGARTTYYTNCAYGARYTNGAR GARAARATGGARGTNGCNMGNYTNCARATGCARATHTAYMGNAGYYTNTGYAAYATGACN GGNACNYTNCCNGTNGARGGNGCNAARGCNAARYTNGAYGCNGARYTNTCNGAYATHACN ACNYTNTAYGARGARTTYGCNGAYCCNTTYGAYYTNCARGARGTNAARYTNGCNATHGTN CAYTGYGCNGGNYTNTAYGAYATGGCNYTNATHGARGAYYTNTGGCAYAARATHATHGAY AARGARATHAAYAGYACNGCNCARATGGTNGGNACNGAYMGNATHACNACNATHAGYATH AARYTNACNACNATHGCNAARATGTAYGTNAGYGTNGARMGNTAYTTYCCNGTNGCNYTN ATHYTNMGNCAYYTNGARCARAARTCNTGYGARYTNGAYATHGAYYTNGARTGGGTNTTY AARATGATGYTNGAYGTNGGNGTNCCNTTYGCNAARYTNYTNGARYTNTAYGAYMGNYTN TAYAARTCNAARGAYGTNATHTGGCARACNYTNAAYMGNCCNYTNCAYATGYTNGCNGTN YTNCARGCNTTYATHGAYCAYYTNGCNMGNAAYCCNGCNYTNYTNMGNTCNTCNAGYCCN CCNATGCARGTN---TGGTGYYTNGAYCARGTNGCNTCNTAYYTNGTNGAYYTNGGNGCN YTNGGNGCNTCNGCNCCNAAYGTNGCNGCNYTNATGGCNGGNTTYAARGCNACNCARGCN MGNYTNGARMGNYTN--------------------------------------------- ------YTNMGNCARACNCCNACNGCNCCNMGNACNCARGAYGTNCARTGYTAYGTNCAR CARACNGARACNCARTCNGCNGGNGGNMGNTGYGTNAAYTAYGGNACNMGNTTYCCNTGY YTNGCNGGNATHGAYGCNCARATHAGYMGNCARTGYCAR---------------GARMGN GCNMGNMGNYTNGCNYTNACNCARMGNAAYCARACNMGNMGNMGNGGNMGNMGNGGNMGN MGNMGNMGNAGYMGNMGNACNCAYMGNGGNAAYTAYATHAARCARGGNACNTCNGCNACN TGYGAYTGYMGNYTNGTNAGYGCNGGNTGGCCNACNGGNAARGTNTGGYTNAAYTCNYTN GGNGGNGCNATHGARGGNCARGAYACNGCNACNYTNGTNYTNACNTAYTCNGARCAYGAY CCNAAYCCNACNTAYACNTGYACNGTNTTYCCNTGGYTNGGNCARGGNAGYACNTTYYTN TAYTCNYTNTTYGCNTTYGGNCCNAGYCARYTNTCNATGACNGTNAGYGGNGARCARAAY GAYCCNAAYCARTCNTGYGARTCNGTNCCNMGNCCNGTNAGYGTNACNTGYCARGTNCCN ATHTCNTCNGCNAGYCCNGAYYTNGTNATGACNYTNGARGGNGCNGGNTCNGGNCAYGTN ACNTCNGCNCARMGNYTNGARGGNGARGCNACNTTYGAYATHMGNCCNGAYCARGGNGGN GTNTTYCCNGTNMGNTGYGTNGGNAGYAAYGTNYTNTTYCCNGARYTNAAYGARCARGAY CCNTTYCAYGCN------------CCNCCNACNACNCCNCCNAARYTNAGYGTNGAYAGY GGNYTNGTNAGY------GCNGAYGGNAARACNGTNCARGTNGTNAAYGGNACNCARYTN MGNGTNCAYTGYCARGTNGARGGNGGNTAYCCNCARGTN---AGYGARGTNGTNATHGCN TGYGCNGAYMGNCARGARAARGCNGCNGARCCNCAYGCNTCNYTNYTNGAYCARACNATG GAYMGNTGGGTNTGYGTNTGYTCNGCNACNCAYGAYACNGGNTGYTAYGGNYTNACNACN GTNAARGARTTYCAYATHCCNATHACNGTNCCNAARGGNMGNGAYAARGTNMGNGARYTN TTYATGAARAAYAARCAYGTNACNGAYATHMGNGTNATHGAYATGYTNGTNATHAARGGN CARATGGAYYTNGTNGARACNGCNAAYATHTGGAARCARMGNCAYCAYGTNATGNNNTTY TTYAARGAYACNGTNAAYCCNAARCCNACNGAYTTYYTNAGYAARTTYTAYGARGGNCAR GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GARMGNGGNAARGGNATHATGCAYGCN AGYGAYAGYYTNTAYAARMGNATGTCNTCNCARCCNYTNTAYAARGAYACNTAYGTNGAY CARGARYTNGAYCAYAARGTNAARAARGTNTCNGAYAARYTNTCNGARACNATGAAYGTN GTNGCNAAYGARCCNTCNYTNGCNTTYTTYMGNATHCARGARCAYGTNMGNAARACNYTN CCNCARYTNGTNGAYACNAARCAYGARGTNGARGAYGTNCARTCNAARGTNCARGGNTCN TGYTTYGAYGCNGAYTAYGCNATHAAYGCNGTNAARGCNATGCARAGYAGYGCNATHCAY TTYCARAAYATHCARGAYYTNYTNAARAAYGCNATGTTYATGAARCARCARATHTCNTAY GARGAYAAYMGNMGNAARCARGGNMGNAAYAGYCCNATGGCNGGNGAYMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TGYMGNYTNMGNAARGARATGTTYGGN GGNTTYTTYMGNYTNYTNGAYCAYGARTAYGAYGARATHTAYGAYGARACNGGNATHGAY GTNGAYGARMGNAARTTYMGNATGGTNGARTAYGCNAARGCNATGGARAGYACNATHMGN GGNATGGTNCARTTYGCNAAYGCNATHCCNGGNTTYGCNCARYTNTCNACNGARGARAAR YTNAAYYTNATHAARTAYTCNMGNCARGARTTYTGYTTYYTNAAYYTNTTYAARTAYGTN AAYACNGARYTNMGNGTNTAYMGNGGNGTNGARGARCARTGGCARTGYAGYYTNGARATG GARAAYTCNGAYTAYMGNMGNTCNYTNGAYGGNATHTTYTAYTTYYTNTCNMGNTTYCAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARACNGGNATHCCNATHACNAAYTCNATGTTYGCNTGYYTNAAYYTN GARGAYGAYATHMGNGARGARAARAARGCNMGNMGNAAR---GCNAARAAYGARAAYAAY GAYAAYAAYTCNAARAARGAYGAYAARAARAARAAYAAYAAYAAYGARGTNMGNCARYTN CARCARYTNGCNTTYGGNAARCCN---TCNTCNGCNGGNAARAARAARTCNGGNAARCAR ---GCNAAYGTNAARACNGARCARAAR------TTYGAYGARTGGAARCARCAYGAYAAR GCNGTNGTNGARGAYYTNTTYCARGAYGAYYTNGARACNGCNYTNYTNGARAGYMGNYTN CARATGGARCARAAR---------GTNTCNGCNGAYAARGARAARCARGARAAYGAYGCN GAYATHCCNACNACNAARGARGARAARAARAARAARAARCARAARGARAARCCNAARGCN ATGTCNYTNCARGARTTYAARCARYTNCCNGGNGGNAARGCNTCNAAYGGNGGNAARGCN TCN------------AAYGGNAGYTCNTCNTCNCCNACNGTNCARCAYMGNGTNCCNGCN AARGARCARGAYGCNGARTTYTTYAARGAYGTNCAYAARGARGCNAARCAYATHMGNAAR CARGAYAARATGCARGARGARTAYMGNAARACNTAYGCNGTNGAYAAYGCNATHGTNGCN AARYTNAARTAYGAYYTNGARYTNAARGAYCARAARATGGARGARYTNACNAAYCARATG AARAARYTNGARGCNGARACNAARCARGTNAARCAYMGNAAYAARCARYTNTGYGTNATH YTNGCNCARGGNGARATGAARGAYAARGCNCARGTNYTNYTNCARGTNGAYGARYTNAAY GCNGTNAARGAYGARYTNACNGARCARGTNACNACNYTNACNGCNGARYTNGARAARGAR AARTCNAARACNMGNGCNYTNAARGCNGARGCNGAYAARYTNAARGGNCAYAARCAYAAY AAR--------------------------------------------------------- ------------------------------------------------------------ ---------------TTYTGYTCNTTYTCNACNGCNAAYAARTCNYTNATHAARTAYTGY CCNTAYGARTCNTTYTGYMGNTCNGAYATHYTNMGNCAYTCNTGYAARATGCAYGCNGAR TTYCARGAYATGGCNGARAAYYTNAAYTAYTGYACNTTYYTNTCNGAYTAYATHMGNGTN AARACNMGNGCNGARGGNAARGARAAY------------GAYGTNGAYGARGAYGTNAAY GARYTNGAYACNGAYGCNATGCARTCNTGYCARGCNYTNMGNAARCAYYTNGAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNYTNYTNCCNGARAARCAYYTNGGNATGGAR YTNAARGARATHTTYCCNCAYATGYTNAARATGAARCARAARTTYGGNYTNAAYGARTGY GGNGARGGNGGNGARTAYGARACNTTYGTNTTYGAYTGYCCNYTNTTYAARAARTCNATH GTNATHGARGARMGNGARYTNGTNATHCAYTCNAAYGAYGCNTTYGCNCCNGTNGGNTAY YTNAAYYTNAARAARTGYCAYYTNAARGAYAARCCNCARGTNGAYGCNGTNTCNYTNGTN GARACNGTNGARAARYTNCCNYTNATGAAYACNTCNAARTGGYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATHCARGCNYTNAARATGGARYTNTCNGAR GARAARTCNAAYTGYAARGTNGCNACNMGNAAYGCNGAYMGNATHAARGARGARYTNGCN GTNYTNGARAARMGNTTYMGNATGTCNGARGARGARAAYGCNTCNYTNMGNMGNAARATH GARYTNGTNAARAAYGARTTYGARGCNCARAGYCARYTNGCNGARGAYGAYYTNAAYMGN GTNTCNMGNYTNGARTCNCARYTNAGYGGNGCNCARATHGARYTNGARAARYTNGARAAR CARCARATHACNYTNGTNCAYGARATHGCNATHGARATHGAYGCNYTNGTNGARACNGCN TCNATHGAYGCNACNAGYAARTGYCARCCNATHAAYGGNYTNAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CCNTTYCARCAYGCNCARGTNGGNACNTTY TTYCARCARCCNCCNTCNYTNMGNAAYCCNTAYCARGARGAYCCNYTNYTNAARAGYTTY YTNCARMGNCAYGTNTCNAGYCARATGTTYCCNGARATGGARGCNGAYYTNTCNMGNTTY GGNGAYMGNGTNGCNGGNGARYTNTTYGAYYTNTCNGTNCARATGGARGCNGARAARCCN GARYTNAARCARTTYAAYGCNTGGGGNCAYMGNGTNGAYGARYTNATHACNAGYTCNGCN TGGAARAARATGAARGAYGTNTCNGCNGARGARGGNYTNGTNTCNTGYGGNTAYGARMGN AARTTYGGNGARTGGAGYMGNYTNTTYCARTTYTCNAARTTYTAYYTNTTYGARCCNTCN GCNGGNYTNTAYACNTGYCCNYTNGCNATGACNAAYGGNGCNGCNMGNACNYTNGARATG AGYGAYGARGAYMGNGARATHGAYATHGARAGYGAYGCNGAYGAYGARGAYGGNYTNAAY CCNTTYAGYTCNGTNGAYGAYAARMGNGCNCAYCAYAAYGCNYTNGARMGNAARMGNMGN GAYCAYATHAARGAYAGYTTYCAYAGYYTNMGNGAYTGYGTNCCNYTNGAYGAYCARAAR ACNAAYTCNTCNAGYAARAGYGGNACNTCNMGNGCNCARATHYTNMGNCARGCNTCNGAY TAYATHATHMGNATGMGNGARAARACNTCNCARAAYGAYMGNCAYATHCARATHYTNAAR CARCARAAYGAYGARYTNCARGCNCARATHAARGCNYTNCARAARTCNCARGCNGGNGGN AARGCNYTNATHAAYTCNAGYTTYYTNGAYGAYMGNGGNGAYGAYGAYTAYGARAGYTAY GAYGAYGARCCNGTNGTNGCNGCNCCNCCNCCNGCNAARMGNAARAARGTNAARGGNGGN ------------------------------------------------------------ ---------------CAYAGY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TGYAARGCNGCN GTNAAYYTNGAYGAYCCNYTNGTNGCNGAYGTNGTNYTNTTYAARCCNAARGCNYTNATG AAYATHAAYGGNGARAAYGTNGCNAARAGYGCNMGNAARYTNGGNGTNAARGCNGAYACN ATHTAYYTNATHCAYGAYGARYTNGAYYTNGCNGTNGGNAARTGYGCNATGAARGAYGGN GGNAGYGCNMGNGGNCAYMGNGGNGTNCARTCNTGYATHGCNTCNYTNCARTCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNACNTGYCCNCCNTCNAARAGYAAYAARATGATHGTNACNTCNMGNTCNGGNGAY AGYTAYGTNACNGCNTCNGAYAAYACNGARGTNYTNCCNGTNCCNAARAARGTNAAYATG GAYCAYYTNAARACNTGYCCNATHYTNGGNCARCCNTCNGGNGAYACNCAYYTNYTNMGN GAYGAYGAYGCNTCNAGYGAYMGNCCNYTNCAYACNMGNTAYATHCCNTCNCCNGCNATG GTNAGYAGYGAYGARGAYAARGARAAYATGCAYAGYAARCCNTCNMGNCARGCNGTNACN GCNCCNTCNGGNYTNACNCCNGTNCARGARGGNGTNGGNAARACNTTYGTNAARCCNAAR GCNTTYYTNACNYTNGARGAYATHMGNGCNGAYACNGGNTCNGCNGTNGAYGAYGAYGTN ATGTCNGTNTCNATGATGTCNGTNGCNTCNAGYGCNTCNYTNGCNTCNCARGTNYTNGAR MGNGCNMGNAARMGNCARAARGAYTTYTGG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARACNGGN AAYMGNCARTGGYTNCAYCCNGCNGAYGCNYTNGTNAARGGNCAYATHYTNTAYACNGTN AARTTYYTNGGNGARTGYAARGTNGARCARGCNAARGGNACNGAYGTNGTNAARTCNGCN ATHACNAARATGAARTTYAAYAARCAYATHAARMGNGCNGARGGNCARAARCCNCCNAAR GTNGARYTNACNATHTCNTCNGAYGCNGTNAARATHYTNGAYCCNAARGGNAARGCNATH YTNCAYCARTAYCCNYTNCAYMGNATHTCNTAYTGYGCNGAYGAYAARTCNGAYAARMGN ATGTTYACNTTYATHGGNAARGCNGCNGAYAAYAAYGAYCAYTTYTGYTAYGTNTTYGAY AGYGAYAARTGYGCNGARGARATHACNYTNACNATHGGNCARGCNTTYGARYTNGCNTAY AARMGNTTYATHGARACNTCNAGYCCNGAYACNAGYATGMGNAARCARTTYYTNACNATG CARAARAARGTNCARACNYTNCARTTYGARAAYGARGTNYTNAARAARMGNYTNAARGAR YTNGARGGNYTNAARGAYMGNACNGAYGTNTCNCARTAYAARCAYAAYAAYCARYTNAAY GAYATHACNACNGTNMGNYTNAAYYTNMGNGARAGYTCNACNGAYGAYGAYGARAGYGCN GGNTCNAAYGARTCNATHAAYAAYAARGCNACNGTNGTNGGNMGNMGNYTNGARAAYYTN ATHYTNGCN------------------GGNGARGCNAARGCNCARGCNGARACNAAYGGN ---GTNCAYGGNCCNCARGAYCAYATHGCNCAYCCNGAYACNCCNATHYTNAGYCCNCCN CCNGCNAAYACNMGNCCNGGNMGNGCNCAYTCNTCNCARATGAAYTCNYTNAAYAAYGTN ------------------AAYAAYAAYAAYAARTCNAGYTTYGGNGAYTCNTCNAGYCCN ACNGAYGTN------TTYGGNATGCARGCNTTYAAYCCNACNCCNTCN---TCNCARCAR GARATHATGGAYATHMGNGAYGGNTTYAGYMGNGGNYTNTCNTTYGGNACNGAYGAYTTY AAYYTNGAYGAYYTNGAYCCNYTNAAYCARMGNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNCCNCARTCNCCNYTNTCNAARGGNGTNAARMGN ACNCAYAAYGARYTNGARGARCARGAYGAYTTYTCNTCNTCNCCNAARCCNTCNCCNCAR AARAAYAARAARMGNTGYTTYACNTGYAGYTGYAARYTNGARYTNGCNCARMGNACNATH GGNAARTGYMGNTGYGARMGNGTNTTYTGYCCNATHCAYMGNYTNCCNGARYTNCAYGAY TGYGARTTYAAYCAYAARGARGAYGGNMGNMGNGARGCNMGNGARAARATGGTNAARCCN ACNMGNCAYATGGGNACNTCNTTYMGNMGNGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGTCNGGNATHACNTGYYTNGCNTGYAAYGTNGGNTTYGARGAY YTNGAYYTNGGNMGNGTNCAYTAYAARACNGAYTGGCAYMGNTAYAAYYTNAARMGNAAR GTNGCNAGYYTNCCNCCNGTNACNYTNCARAARTTYGARGARMGNCARAARGCNCARGAY ------GARCAR---GAYTCNAAYGTNATHCARGARAGYTGYTAYTGYAARCCNTGYAAY AARTCNTTYAGYTCNTCNAAYGCNTAYGARAAYCAYYTNCARTCNAARAARCAYAARGAY ATHATHTCNTCNAARMGNAGYAARAARAARTCNMGNCARMGNACNGCNYTNGCNTCNCAR GGNGGNTCNCARAARYTNGCNYTNAARACNGARGAYGCNATHGCNGARMGNATGTCNTGY GAYGARGAYGAYTCNGAYGCNGARTCNYTNGAYAGYTAYGAYGARGARGTNYTNGGNATH GARGARTGYYTNTTYTGYTCNTTYATHAGYYTNTCNYTNGARGAYAAYYTNGCNCAYATG ACNTCNTAYCAYGGNTTYTTYYTNCCNGAYGCNGARTAYATHTGYGAYYTNGARGGNYTN ATHACNTAYYTNGGNGARAARGTNGGNGCNGGNCAYGTNTGYYTNTGGTGYAAYGAYAAR GGNAARGCNTTYCAYAAYTGYAARGAYGTNCARMGNCAYATGGTNGAYAARGGNCAYTGY AARATHYTNCAYATHGGNCARACNYTNTAYGARTTYGCNGAYTTYTAYGAYTAYTCNAAR AGYTAYCCN------GAYGCNTGYAAYCARAAYACNTCNAAYGARATHGARGCNGTNGAY ACNATGGARYTNGAYGGNGAYGGNTTYTCNYTNACNYTNCCNTCNGGNTCNGTNATHGGN CAYMGNTCNYTNATGMGNTAYTAYCAYCARAAYYTNGTNCCNTCNATGMGNGARGGNACN MGNAARATGYTNCCNAARATGYTNGCNCAYTAYAARGCNYTNGGNTGGGCNGGNGCNACN GGNACNYTNGTNGARCARACNGCNAARGAYYTNCAYTTYATGCAYMGNGCNMGNAARAAR CAYTTYATGAARYTNGGNATHAARGCNAAYAARYTNATGCAYCAYTTYMGNGAYTCNAAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CCN MGNYTNYTNTGYGTNATGYTNMGNTAYTGYTCNGTNGAYATHYTNCCNYTNGTNGAYCAY AGYATHGGNGARATHYTNGAYAGYYTNGAYGAYCAYTAYGTNGARGARGTNGTNTGYTTY ATGCCNGTNYTNYTNGARYTNACNTCNGCNATHGGNMGNTGGTTYCCNCCNYTNGCNCCN TCNGCNGCNGGNCARAGYAGYAARCCNAARGARACNGCNGAR---------TCNYTNGTN TCNAGYYTNGARGARTAYGTNAARYTNAAR------GCNGARGCNGARGGNGAYATHTCN GAYGARGAYGARGGNCARGARGGNGARGGNAARMGNACNYTNGARGAYATHGCNAARGAY YTNAAYAARYTNMGNGARGARMGNGARCARGARAARGAY--------------------- ---GARGARTCNATGGARGARGAYGARGARAARCCNAARGARTGYCCNAARCAYATHAAR GTNGTNAARGARGTNYTNYTNMGNGTNAARAAYYTNYTNTCNTCNCAYGAYGCNMGNATH MGNGTNCARTCNYTNGARGTNATGGCNCARAGYTGYAARGAYYTNGCNGAYCAYGARMGN GARYTNYTNCCNCARATHCAYCARYTNTGGCCNGGNTTYTAYCCNMGNTTYCAYAGYGAR GARAARTTYGTNGTNATHAARGCNYTNCARACNYTNTGYGTNATGGCNGAYGTNGCNGGN AGYTTYATHCARCAYMGNGTNATGAARGAYGTNATHCCNGTNYTNMGNCARTTYATGGAY AARCARGCNACNATHAGYTGYGARAGYMGNTCNACNTAYACNCAYACNGCNTGYTTYAAR YTNCARYTNGCNGTNYTNCARGARATHGGNGCNYTNACNCARMGNYTNGARGTNGARGGN AARAAYYTNGAYACNGTNGCNAAYATHTGYYTNCCNTAYYTNAGYGAYYTNCARCCNGAR AARYTNCARAARGCNTCNYTNGCNGCNTTYTCNTCNTTYGTNTCNGTNGAYTCNGAYGCN ACNTGGYTNYTNYTNTGYCARGCNTAYTGYCCNTAYTGYTAYACNYTNCCNGGNTCNGAR TTYGCNCCNYTNTTYCARTTYGCNGGNGARGAYTAYGGNCCNGTNGAYTTYCCNAGYTCN YTNCCNGCNGAYYTNCARGCNGGNATGGCNTTYGCNGGNGGNGGNCCNGTNTTYCCNCAR AAYCARMGNGGNGGNACNTAYGGNATGCCNGCNTTYCAYATGAAYTAYTCNCARCARGCN TCNATGCCNCCNATGTCNAGYYTNCCNACNAGYTCNTTYMGNAGYMGNTTYGGNGAYTTY CCNTCNGAYCARAGYCCNCAYYTNCCNATGCCNATHCCNTCNCCNGCNTCNGGNATGATG GCNGAYMGNYTNCCNAGYTTYAGYACNATHGTNTCNAGYAGYGGNGGNAGYGARYTNTCN AARAGYAGYCARGCNYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AAYTTYAGYATHGAR CCNYTNGAYGTNGCNGCNCAYYTNAARYTNYTNGGNGARTCNYTNAGYATHATHGGNATG MGNYTNCARGARCAYAARGGNATGATHGCNGTNCARGGNAGYYTNTCNGTNYTNYTNGAY TCNYTNYTNTGYGCNTGYGGNCCNYTNYTNTGYYTNACNCARCARGTNCCNGGNATGGAY GGNTGYTCNGCNTCNGTNCAYGCNCARACNYTNGAYAGYGTNGCNTAYGTNATGCCNGGN YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CCNCCNCARGGNTAYGGNGGNGCNCCNCCNCCN CARGGNTAYGGNGGNCCNCCNGGNTAYGGNCCNCCNCCNCARGGNTAYGGNGCNCCNCCN CCNCARGGNTAYGGNGCNCCNCCNCCNCARGGNTAYGGNGGNCCNCCNCCNCARGGNTAY GGNGGNGCNCCNCCNCARAGYTAYGGNGCNCCNTAYGGNCARGCNCCNTAYCCNCARCAR CCNTAYTAYCAYGGN------CARCCNCARCARCCNCARCARGTNGTNTAYATHMGNGAR ACNMGNAARGARAAR---AARGAYAAYTCNGCNGARACNTGYTGYATHGTNGCNYTNTGY AGYGCNYTNATHTGYTGYTGYYTNATG---ATGGCNGAYAGYAAYYTNCCNMGNCARGAY TTYGCNCCNCCNTGGYTNAARTTYCCNTCNGARACNGTNAARTCNGCNAAYCARAARCCN AAYACNTAYCARAGYGAYMGNAAYMGNCCNMGNMGNGARGAYCCNTAYTAYTCNMGNTCN GAYTTYAGYMGNYTNCAYMGNCARAAYTCNTTYGAYTTYCAYGARGGNAARMGNTAYCCN TCNGGNCCNAGYAARTAYMGNCAYCAYTCNGTNGAYGAYGAYTAYGGNGGNTAYTCNTAY GGNTAYGGNTAYTAYCCNTCNAAYTAYAAYTAYGARAARTAYGGNATGCAYTTYAGYTCN CARCCNTCNYTNGCNMGNTCNGGNAGYMGNGAYGGNAARTAYCCNCCNGGNMGNYTNAAY CARATGAAYGGNAAYGCNYTNYTNAAYGGNCCNCAYGAYATGTTYGARCCNTAYTAYCAR CARGGNTCNAARMGNGGNTAYMGNGARAAYTGYCAY---AARGAYATGMGNAAYGGNGAY GGNAARGAYAARGAYMGNGGNAGYGARAARGAYMGNCCNTTYACNGAYGAYTTYCCNTCN YTNAAYGGNTCNGGNGARACNGCNACNGAYTCNAARACNAARCCNGGNTCNGGNGTNTGG GARAAYCCNCCNAAR---TCNGCNAAYMGNAAYGARGARTCNACNGAYATGYTNAARAAY TCNTCNCCNGGNATHTAYAARGCNYTNGTNCCNAGYAARAAYGTNCARCCNAARAARAAY GCNAARGARGTNGTNAARGTNAAYGGNAGYGTNMGNGARGTNTCNCCNYTNAGYCCNTCN AAYAARTCNAGYCAYAARGARGGNTCNMGNTAYAGYCCNACNCCNGAYYTNGCNATHGTN ACNCARCCNAARAARYTNGGNGAYAARAARAGYGAYTTYYTNMGNGCNATHMGNAAYGAR AGYTCNATHMGNAAYGGNGAYATGTTYCARAAYCARAAYCARAAYCARGTNTCNAARCAR GAYGAYGGNGARGARAARGARAARAAYCCNAGYTAYMGNYTNGTNAAYGGNGARMGNCAR GTNGAYACNAAYGARAAYGTNYTN---------------ACNGTNAAYGGNGAYYTNAAY GGNGARTTYGARGAYTCNATHTGYAAYGARTTYGGNGTNAAYGGNGAYGCNYTNATHAAY CAYGTNGAYCAYATHACNYTNTCNGGNGARGARGARGARMGNMGNYTNYTNYTNTCNATG GGNTGGGTNGARGARGAYAAYACNGARTAYGTNATHACNGAYGAYGARATHMGNGARTTY CARAAYYTNGTNCARAAYCAYMGNCAYGGNCARAARAAYGGNYTNAARTCNTCNYTNMGN AGYGCNYTNGAYMGNMGNATHGGNGTNGAYAGYGTN------YTNAAYGGNATHCCNTCN GARGARGARAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYGGNMGNTAYCCNMGNGARTAYAAYCCNAARGTNCAYGGN CCNTAYATGCCNGGNMGNTTYTAYGGNAARCCNGAYGTNCCNGTNGGNGAYGTNAARYTN GGNGARYTNGGNTCNTGGTTYGGNMGNMGNAAYAARAGYCCNCARGGNATGTGGAGYTGY YTNCAYMGNGCNTAYTGGMGNTGGGCNGCNAAYAAYTTYCAYGTNMGNCARGCNGGNTTY GTNCCNYTNGGNCARGCNGCNATGGTNATGTCNGCNTTYTAYTTYGTNYTNYTNTAYAAR GARMGNAGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNCARTCNACNCARGAYCARYTNAGYCARMGNGTNACNGARATH GTNMGNCAYGARCARAAYTCNMGNAARYTNCARGCNGARYTNAARGCNGTNAARGARMGN GCNGGNGCNTAYGARGARGARATGGARGAYCARAARGTNATGATHGAYAARYTNMGNAAR GAYYTNGTNGAYACNAARGARGARTAYCAYTCNTCNGTNCARGARGGNATHGCNTAYAAR CARCARGCNCAYAARAAYGARYTNGARYTNTCNGGNAGYMGNGARCARGARAARATGYTN TCNGAYCARGTNGARCARCARGARCARATHYTNAAYCARYTNCARACNGARYTNMGNGCN GARMGNGARMGNCAYGCNGAYACNGTNAARCARYTNAGYGCNAGYAARAARAAYGGNYTN GAYYTNCARGCNGAYYTNGARGCNYTNCARAARCARGCNMGNGARYTNCARGAYMGNGTN AARTCNMGNGARGARCARATGATHMGNYTNMGNCAYGARATHGAYAGYYTNCARCARAAR AAYMGNGAYAAYAAYGARCARATGGCNGARAARGAYGGNCARYTNMGNYTNGCNGARATG AAYYTNCARACNGCNCARAARCARGCNAARCAYCAYACNCARGARATHGGNMGNTAYGAR GAYACNYTNGCNCARYTNCARACNGAYCARGARAARYTNCARGARCARTAYMGNCARTCN TCNTCNAAYYTNATGGARGCNGARAGYAARGTNCAYGARYTNAARGTNCARYTNACNGCN YTNCARGGNCAYCAYAARGARGCNATGGAYCARYTNACNGAYAARTCNMGNCARYTNGCN GGNATHAARACNGARGCNGCNAARATGGCNCARCARAAYAAYTCNATGAARGARGARATH ATGGTNTAYGAYGARAARATGMGNAARATGCAYCARGARYTNMGNAARTCNCAYGARYTN AAYAARGCNACNGARGARGARYTNMGNCAYTTYGARGARMGNTAYACNAGYYTNCARGTN GAYYTNGTNTCNAGYCARGARAARCARAARCAYTCNYTNCARGARYTNTCNTCNAGYGAR GARGARATGGTNGTNATGAARGTNGARYTNAGYTCNYTNCARGARAARTAYAARACNGTN AAYGAYGARGTNCARAARYTNACNAGYGAYYTNGARYTNACNAARCARAAYTAYMGNAGY GCNACNGARGARATHTCNGGNYTNMGNGTNGCNYTNGARGARTCNMGNGCNAAYGGNGAY MGNYTNCAYMGNGARTCNGARYTNGTNGTNCAYAAYGTNAAYACNTGGGTNCARGARCAR AARATGGCNAAYGARAARYTNGGNAAYAARATHMGNGARCARAGYAARTCNATHATGGCN YTNAGYTCNGARAARGARATGTAYYTNGARCARATHACNAARYTNCARAARAAYTAYAGY AARACNAARAAYGARYTNGARGAYAARACNGTNGARGGNGAYAARYTNMGNGCNYTNCAR TCNCAYTCNGCNCAYCARCARGTNATHYTNAAYCARYTNAARAGYMGNYTNGARGARCAY GARYTNGAYAARGAYCARGAYYTNAARACNAARGTNGCNACNATHGARGAYYTNCAYCAY MGNYTNAARTCNAAYATHGAYAGYATHCAYCARYTNAAYCARCARYTNAGYTCNYTNCAR AARGAYAAYGTNMGNYTNMGNAAYGARYTNGAYMGNGARGTNGCNACNMGNCARACNYTN GARATGCARATGCARGGNAARGARCARYTNGTNGARAGYYTNMGNTGYCARYTNGAYTCN ACNAGYTAYAARCAYYTNYTNGARAARGCNGARAGYATGAARGAYCCNGARAARYTNAAR ATHATGGAYYTN------------GARAARTGYTCN---ACNGTNCCNTCNGARAGYGAY ATHAGY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGNGGNCARMGNGAYMGNYTNMGNCARATGMGNTAY GAYAAYMGNMGNGTNACNGTNCARGGNYTNACN---------AAYCAYCCNGCNCCNAGY GGNYTNTAYGARGAYAGYCARTCNGARGAYAGYGGNTCNCCNMGNCCNGARYTNTCNGAR AAYYTNGTNTCNGCNTAYAARAAYATGAGYAARGARGARYTNGTNMGNGTNYTNATHCAR ACNAARGCNCARACNATHMGNAARGAYCARTAYACNMGNGAYYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AGYCAYAAYCAYCAYTAYGTNTAYCAYCAYCAYCAYCAYCARCARGCNCARTTYCCNGCN AARACNACNCCNTTYGCNGARCARCAYAGYAAYCARCARCAYGCNCARCAYGTNGAYAAY AARTCNGGNTTYYTNMGNAARTCNTTYGCNTCNTTYMGNGCNATGMGNAARCARGGNGTN MGNGGNAARGARCARGAYCARCCNMGNCCNCCNGCNACNTCNGGNGARGTNMGNTGYATG GTNTGYCCNTAYCCNGARACNGGNATGCCNGCNGAYMGNAARCCNTCN------------ ---AARCARTCNMGNAARGGNYTNMGNGGNYTNACNAARCCNAARAARCAYGAYGAYCAY GTNTCNGGN------GAYAARGCNTGGTAYTCNGAYCAYGARTCNCAYTCNGCNATHMGN CCNGTNYTNTCNTGYAGYGAYACNYTNCCNTAYCAY---TCNTTYMGNCARTTYCCNGTN MGNGARTGYTCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARAARGARYTNGARTGGGAYGARATGAAYATHYTNGCNACNCAYCAYCCNCCN GAYAARGAYTAYGGNTTYATGAARGTNGAYGARCCNCCNACNCCNTAYAAYAARGCNTCN YTNTCNGAYGTNGARGAYGAR---GARCAYYTNGARMGNAARGGNAGYGTNGARGGNYTN AARGGNYTNGAYCCNGCNGAYYTNGCNTCNMGNYTN---GCNGCNGGNTCNAAYMGNGCN AAYAARATGTTYGARGARGARGARGARGARGARTCNGARGAYGARACNGARYTNTCNGAR GARGARAARGCNMGNAARAARGTNTTY--------------------------------- ------------------------------------------------------------ ------ATGGGNACNMGNTGYGCNGGNGAYATGMGNATHACNTAYGTNGAYATHGGNGAR ACNATHGCNCARMGNMGNMGNMGNACNGGNACNTTYAARAGYACN---GGNCCNCCNCCN GARMGNMGNTGYACNATHAGYAGYGGNACNATGACNAAYAGYTAYCARGTNACNMGNATG MGNAAYYTNTCNGGNGGNAGYAGYGGNAGYACNGCNAGYGGNTGYAGYAGYGGNAGYTCN ACNCARYTNGAYAAYCARTTYTCN------TCNGAYAAYCAYATGTAYTTYTCNYTNGAY ATHTCNACNTTYGCNAAYTCNTCNGTNCARGGNMGN------------GGNGARTCNTCN TGYTCNTAYMGNAARYTNGAYMGNAGYYTNAGYGAYTGYGAYAAY---------TCNGGN AGYAAYAAYTCNYTNCARAARTCNGTNAAYTCNAGYMGNTAYAARACNGARYTNTGYMGN CCNTTYGARGARAGYGGNTCNTGYAARTAYGGNGAYAARTGYCARTTYGCNCAYGGNGGN CAYGARYTNMGNAAYYTNGCNMGNCAYCCNAARTAYAARACNGARYTNTGYMGNACNTTY CAYACNATHGGNTTYTGYCCNTAYGGNCCNMGNTGYCAYTTYATHCAYGARGAYGAY--- ------------------------------------------------AARGGNGAYACN AARATHACNAAYAGYGGNAGYAGYAGYCCNACNYTNAGYCCNACNGGNAGYGAYCARGAY ------AARTTYTCNTAYTCNGAYTCNTCNAAYTCNAAYATGGAYAARGCNCAYCARGCN GAYAAY---------TCNYTNACNGTNAAYATHAAYAAY------AAYTTYGGNAAYGTN GAYGTNCARTCNYTNGARCARCAR---TTYAAYTCNACNYTNAAYYTNAAYMGN------ ------------------------------------------AGYTGYGARTCNTCNMGN AAYAGYAAYGGNAARTCNGAYTAYGAYATHTTYAGYTGYATHTCNGTNTTYAAYCCNGCN GARGTN------GAYAAYGARCCNAARCCNTCNAGYTCNGTNYTNCARCCN--------- ------------YTNGAYAAYTAYCCNACNTTYGTNGAYACNTCNTGYTTYTGGCCNTCN ------AAYGTNTCNTCNCARAGYGTNGCNCCNGTNGAYCCNTAYCAYCAYTCNCCNACN GGNTCNACNGGNTCN------------------------TAYTCNAGYGGNAGYGAYTGY AGYGGNAGYACNGARAGYYTNGCNAGYTCNGGNTAYMGNGARAARMGNACNGCNTGGTGG AAYGAYAGYGTNAARGCNAARATHAARGARAARAARGAYGCNTGGAARAARTAYYTNAGY AGYAARYTNCARGARGAYMGNGARGAYTAYAARYTNAARMGNCARGCNGCNAARGARGAR GTNYTNAARTCNAARCARATHCARTGGCARAARTTYGGNGARACNYTNGARCARAAYTAY AAYGARAAYCARAARYTNTTYTGGGGNGCNATHAARMGNTGYMGNMGNGGNAARTCNTGY CCNATHAARCAYATGGTNAAYTCNGAYGGNGARGTNATHAARCARGARGAYCARATHYTN GARACNTGGAARCARTAYTTYGARAARYTNCAYAAYATHGGNACNGAYGAYAAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNGARAGY GCNTTYGTNGGNMGNMGNGAYGTNMGNAAYCCNGGNACNGTNCCNGARAARGARATHYTN AGYGARAARGGNACNGTNMGNGGNTTYACNAAYMGNGTNMGNGCNGGNATHGCNACNTTY TGGGCNCAYCCNGARGAYCARMGNAAYTAYMGNGARYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNGCNTCNTAYTGYAARAAY ATHYTNYTNAAYCARGTNGTNTCNGARAAYTGYGGNGTNTAYYTNTCNACNTCNAARYTN GCNAARGTNTAYGGNATHGCNAAYATHATHGTNAARAARATHCARACNAARAAYAAYYTN TCNGCNGGNTTYATHACNGAYTCNAGYAARATHGAYATHCARTCNGTNACNAGYAARGCN TAYTAYGAYYTNYTNTCNCAYGARGGNGARAAYYTNACNAARYTNGGNGGNYTNGARYTN GARTTYMGNAARYTNGARAARYTNTTYYTNATHAAYAARTCNTCNTGY---ACNTAYTAY MGNCCNYTNGGNATHYTNYTNCAYGGNCCNCCNGGNTGYGGNAARACNTCNTTYGGNAAR ATHYTNGCNAARCARTGYAAYGCNGCNTTYTAYAAYGTNGAYGCNTCNTCNYTNYTNGAY TCNGAYTTYGGNGCNGGNGCNGAYAAYYTNCAYMGNATHTTYCARAARGCNGTNGAYYTN ACNGARGARGGNCCNGTNATHYTNTTYYTNGAYGARATHGAYATGYTNTGYCCNMGNCAR GARACNGCNAGYYTNGGNAAYAARCARYTNAGYGCNGCNYTNATGAAYGARYTNGAYGCN GTNAAYTGYAARMGNATHTCNGGNYTNYTNGTNYTNGCNGCNACNAAYTCNATHTCNAAY GTNGAYTCNGGNYTNMGNMGNCCNGGNMGNTTYGAYCARGARATHYTNATHAGYGTNCCN ACNGARMGNCARMGNYTNTCNATHYTNGARATHGTNACNGCNAARATGCAYYTNGCNCAR GAYGTNTCNTGYGCNGCNYTNGCNAAYATGACNCCNGGNTTYGTNGGNGCNGAYYTNMGN GGNYTNTCNGARGARGCNYTNGGNCAYGCNGARACNGCNCARTTYCARGAYCCNCARGTN ------YTNMGNATGGARGAYTTYCAYTTYGCNYTNCAYAARACNATHCCNTCNYTNAAR AARGGNTCNGARTGYGTNGTNGAYYTNAARCCNGTNAARTGGACNGAYATHGGNAGYYTN GARGAYGTNAARGCNGARATHAARCARTCNGTNGARTGGCCNYTNAARTAYCCNGARATH YTNCARAGYATGGAYATHCCNCCNGCNAARGGNATHYTNYTNTAYGGNCCNCCNGGNTGY TGYAARACNACNYTNGTNMGNGCNGTNGCNACNTCNTGYAAYGTNTCNTTYYTNTCNYTN AGYGGNGCNCARGTNTTYTCNGCNTAYGTNGGNGARTCNGARMGNTTYATHTCNCARGCN TTYCARAARGCNMGNGCNYTNGCNCCNTCNATHYTNTTYYTNGAYGARATHGARTCNATH GTNGGNAARMGNMGNTCNGAYGTNGGNAAYAAYMGNGTNCARGARMGNGTNYTNTCNACN YTNYTNAAYGARATGGAYGGNGTNGGNAAYMGNYTNGAYYTNAARYTNGARTCNTCNTTY TCNCAYAARGARACNGGNAARACNGTN------------------------------ATG CARAARACNCAYYTNACNTGYGARAAYTAYGARAAYGAYGCNGARATHACNGARTCNCCN AARGGNAAYAAYYTNAARGTNATHGGNGCNACNAAYMGNCCNGAYATGYTNGAYCCNGCN ATHYTNMGNCCNGGNMGNYTNGAYAARCAYATHTAYGTNCCNCCNCCNGAYGARAARGCN MGNAARGAYATHYTNGARATHTAYACNTCNAARATGTCNTGYCCNGAYATHGAYGTNGAY TAYYTNGCNAGYCARACNGAYYTNTAYAGYGGNGCNGAYYTNAARAAYYTNTGYAARGAR TCNGGNYTNCARGCNGTNMGNAARCARYTNGCNACNTCNGAYCCNGGN------------ ---------------------------------------------------AARGARGTN AGYAARYTNCARTTYGARYTNGARTGGAARGARTCNTCNTTYYTNGAYAGYCARCARACN TGGGCNGARMGNTTYGAYMGNGTNTGYMGNGAYAAYGCNTCNYTNACNTCNAARYTNGAR GCNMGNAGYGARGARYTNMGNMGNGCNACNGCNCAYAARGCNGCNATHGCNMGNGARMGN GAYGARYTNYTNGCNYTNYTNGAYGTNACNGARMGNATGAARTAYGARCARGGNAARAGY ATGATHGCNGARGARGARTAYGGNACNTTYTCNTCNAAYGARYTNGCNGTNYTNGGNGCN TGYAARTGYMGNGGNGCNAAYCCNGARCCNTGYGGNTGYGCNCAYGCNGCNGCNAAYYTN MGNAARGARGTNGTNAARYTNMGNGARGARATHAARGARTCNAAYAARMGNMGNGARGAR GCNGARGARCARATGGCNAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGAAYATHYTNGGNAARGTNAARTTYGGNGTNAAYCAYYTNTAY TCNAARCAYYTNYTNGCNACNAAYACNGTNACNTGYGGNGGNYTNYTNGGNYTNGGNGAY TTYGTNGTNCARCARATHGGNYTNYTNGGNGAYAAR---------CAYTAYGAYTAYGCN MGNACNGGNMGNATGATHGTNGTNGGNTTYTGYYTNGGNCCNTTYAAYCAYTAYTGGTAY AGYTTYYTNGAYAARGCNGTNAARGGNCARGGNATGAAYGTNGTNNNNAARAARATHATH TGYGAYCARTTYGTNGCNGGNCCNTTYTTYTGYACNGCNTTYYTNGCNGGNACNACNYTN ATGGARGGNGCNGGNGTNTCNGGNGCNATHGARGARTGGAARTCNAARTTYYTNTCNATH TAYGTNGTNGAYTGGGCNTTYTGGCCNGCNGCNCARTTYATHAAYTTYMGNTTYYTNCCN ACNMGNTTYMGNGTNYTNTAYGTNAGYTTYGCNACNYTNGTNTGGAAYTCNTTYYTNTCN TAYATGAARCAYAARAGY------------------------------------------ ---------------------------------------------------------CCN TGYTCNACNYTNTTYTAYYTNYTNYTNGTNGTNTTYGGNTTYATHCCNTTYATHTGYTTY TTYYTNTTYATHGGNGGNACNTTYATHYTNACNATHGTNTGGTTYGCNGTNTGYCARGCN GTNYTNGTNACNGTNTCNGCNYTNATGTTYGGNGGNTTYATGATGTTYYTNATHGCNATG TGYTGYTGYATHGCNGGNGTNTTYGGNYTNATHATHCAYACNGTNTAYGGNTGG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNTCNACNCCNGARTGYMGNAARATHYTNAAYGTNCAY AARGAYGAYCARGAYACNATHAAYMGNAARCAYGAYGARCARMGNGCNATGCARGARAAY GCNYTNAARAARAARYTNYTNGCNAARATGGARCARMGNGARCARTCNYTNYTNTTYAAR CARGAYGARGARATGCARAARYTNATHAAYGARGCNACNAAYAAR--------------- ------------------------------------------------------------ ------------AAYGAYGAYGGNTTYATHTCNTGGGARGARTTYGTNTCNTTYTTYGCN GAYGGNGTNATGGGNAARCARGARYTNCARGAYYTNTTYAAYGARATHGAYTCNCAYAAY ACNGAYAAYATHGAYACNTCNGARYTNTGYTCNTAYTTYTCNCARCAYYTNGGNGARTTY AARGARATHTTYGGNYTNGTNGARGAYGTNAAYAARAARATGACNAGYGTNYTNTTYAGY ACNGCNAARGTNTAYAARGAYTCNTCNMGNAARGARAARTTYATHACNMGNTTYYTNATG MGNGARATHGTNAAYCARGTNGTNGCNYTNCARMGNCCNYTNGAYTCNGCNTCNGARACN YTNGAYAGYCARGCNMGNGARGARMGNTCNGAYATHYTNCCNYTNGARYTNGGNGAYGTN AARAARGCN---GGNGGNGARAGYGGNATHGTNCCNGGNMGNGTNGTNMGNMGNGCNAAR MGNCARGTNAGYAAYATGAGYAAY---------------AAYTCNGTNYTNTCNGAYGGN CCNAAYYTNYTNGCNGGNCARYTNGAYAARYTNACNCARYTNATGGAYAARYTNGARTGY AARATHAARTTYGARAAYTTYMGNGAYGARGARGTNGTNACNGGNAARGAYGAYACNGTN YTNYTNGTNCARMGNGARTTYGTNGTNAARGARGAYCARYTNACNAGYTTYMGNGCNCAY YTNMGNTCNTAYGTNGAYYTNACNCARGGNTTYMGNGGNTGYTTYAAYGTNAGYGTNMGN GAYATGMGNCARAGYCAYMGNTTYAGYATHTAYGARGTNTGGTGYGAYGARGARCAYTAY MGNYTNAAYTGYGARAGYGARGCNGCNACNTCNYTNGTNAGYCAYACNTCNGAYYTNYTN GARAARCCNGARACNGTNCARTCNATGGCNATHCCNGGNTCNTGGTGG------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY GAYACNATHAGYTGYYTNAGYGCNGTNTTYTTYTCNTGYYTNGGNYTNACNYTNGTNTGY GTNGTNGCNTTYTAYTCNTGGAARAARTAYCARCAYMGNCARMGNATHCARMGNATHTTY MGNCAYGARCARAAYGAYCCNTTYCARGCNYTNTAYAGYCCNACNCAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGATHGTNGARAARGAYATHGCNYTNATGAARCARAARTGYGTNACN GGNGCNTCNYTNMGN---------ATHGARGAYACNACNMGNCCNYTNCARGGNGTNMGN YTNGCNGCNYTNGARAARAAYTCNTCNGAYATGGARAARYTNATHGAYGARGCNAARACN GARAARYTNMGNCAYATGGARGARGTNCAYGARGGNAAYAARAARGTNGCNGARYTNGAR GCNAARGTNAARCARYTNCAYACNCARYTNGTNGARAARGARGCNGTNYTNAARGTNTTY CAYMGNTCNTCNCCNATHYTNCCNMGNAGYTCNAGYYTNCAYGCNYTNTGYCAYTCNCCN YTNCAYTCNCCNMGNCCNTCNYTNYTNGCNGCNCARGCNYTNGARGGNTCNTCNGCNACN GGNGGNTCNAGYTCNAGYGGNACNCAYMGNGARTTYTCNTCNGTNMGNCAYATGAARACN GGNAGYACNAGYGCNATHGAYATGGGNMGNAARATGTCNGTNGARGARGAYYTNYTNGCN AARGTNCARCAYTTYAAYGTNCARAGYAARGAYGAYTCNGCNGARGARGTNAARYTNTGG CAYGTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AAYYTNATHAARATHAAYGGNATH ACNGGNGAYTTYAARYTNACNGTNGAYATHTAYGGNATGAGYATHTCNMGNGARATGTCN AARGAYAARAARMGNAARACNCCNAARAARGGNAARGGNTAYGGNYTNGCNYTNGARAGY CCNGGNGGNCCNGTNGCNGTNMGNACNACNAGYTTYACNAAYGTNTCNTCNGTNGARYTN ACNATGAARTCNYTNGAYAARTCNTCNTTYCAYYTNGARMGNYTNCCNCARYTNTCNCCN YTNTAYGGNCARATHTTYATGMGNYTNAARTGYGTNATGGARGCNAAYGTNGARGARAAR GGNTTYYTNACNATGTTYGARGAYGTNAGYGGNTTYGGNGCNTGGCAYMGNMGNTGGTGY GTNYTNTCNTCNAAYAARYTNTGYGTNTGGAARTAYCCNGAYGAYGARACNMGNAARGAY CCNATGACNATHATHGAYYTNAARMGNTGYGTNTCNGARAARGTNGGNYTNGTNCCNMGN GAYATHTGYGCNMGNCCNAAYACNTTYGARATGGTNTCNGTNMGNCARCCNYTNAARGGN GARCAYGAYACNYTNGTNTCNAARACNCAYMGNACNATGACNACNGTNMGNCAYCARGTN TCNGCNGAYACNAARGARGARMGNATHATGTGGTGYAAYCARATHAAYMGNACNYTNGCN AAYYTNMGNACNTGGAAYCCNGAYGCNYTNMGNCCNGCNAARGAYTTYGARTCNTCNCAR ATHGGNACNCARGARCAYTGGGAYGARACNTAYCARAARGARYTNGARAAYTTYACNGAR ATHGGNGAYGTNGGNGARATHTGGTTYGGNGARGAYACNCARGAYMGNATGGTNMGNTGG ATHTGYGARAARTCNGAYYTNCCNYTNTCNTCNGTNATGATHGAYYTNGGNTGYGGNAAY GGNATGYTNYTNTTYGCNYTNMGNGARGARGGNTAYACNAAYYTNACNGGNGTNGAYTAY TCNAARTAYTCNGTNGARYTNGCNGARAARATHGCNAARTCNGARGGNGTNACNGAYATH AARTTYGARATHTGYGAYATHYTNTCNTCNGAR------GAYGCNGTNAARMGNGCNGGN YTNTAYGAYGTNTGYYTNGAYAARGGNACNTAYGAYGCNATHAGYYTNAARAAYACNACN GAYCCNACNGAYMGNMGNACNTAYATHTCNCAYGTNCAYTCNATGYTNAARCCNGGNGGN YTNATHGTNYTNACNTCNTGYAAYTGGACNAARCARGARYTNGARYTNCAYTTYGGNCAR AGYTTYGAYYTNAARGAYGARATHCCNGCNCCNAARTTYACNTTYGGNGGNCARACNGGN CARAGYGTNACNTCNYTNATHTTYTCNMGNAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNAAYMGNTAYMGNCCNYTNCCNCCNACNCCNTCN CCNMGNTCN---GGNACNCCNCARTCNATHGGNYTNACNGAYCCNTAYATHAGYYTNTCN TCNGARGAYCARGARTTYACNAAYMGNATHACNTCNATGGGNTTYYTNMGNGCNAARGTN GCNMGNGCNGTNCARAARTTYGGNMGNGAYGARAARGARGTNYTNGAYCAYYTNTTYGCN GTNGAYACNYTNGTNGARMGNAARTTYGCNCCNGTNCAYGCNGARGCNGCNYTNCAYACN TGYAARAAYGAYYTNGAYAARGCNGARAARYTNYTNAARATGCARAGYCARYTNGARGAR YTNGGNTTYACNAGYGARAAYGTNMGNAGYGCNYTNATHAARTCNGAYATGGAYCAYGAY AARGCNYTNGAYATHYTNACN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MGN TGYATHCCNGGNTGYGARGGNGGNCCNYTNTTYTCNAARAARCCN---ACNGAYATHGAY MGNCAYYTNACNGGNATHATHGTNTCNTCNYTNTGYTGGAARAAYAGYGARTGGATHGGN TTYTCNGTNGCNTGYAAYATHAARAGYATHYTNAAYTCNATH------------------ ---------------------------YTNAAYGAYAARAGYATHYTNTCNGTNAARAGY GCNGAYAARCAYATHGTNCCNATGYTNTCNAAYGGNGGNACNGAYYTNGCNCARGAYYTN ACNGTNYTNATHCARTGYGGNAAYTCNTGGGGNTCNGGNGTNATGYTNGAYAARMGNCAR GGNATHTTYYTNACNTGYAGYCAYGTNYTNAAY------GARACNACNCARGTNACNGTN AARTGYTCNMGNAGYMGNAARAARTAYCCNGCNACNATHYTNTAYMGNCARGAYCCNATG ACNGGNCCNTAYGAYYTNGCNYTNATHCARTGYCAYGARGCNTCNMGNAARYTNCCNCAR AAYYTNAAYATGCARGTNTCNTCNCCNGARYTNGGNGAYGAYGTNACNGCNTGYGGNCAY GCNGTNTTYAGYYTNAGYCARGGNYTNCARCCNTCNATHAGYAARGGNGTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNYTNGAYGARTTYATHMGNCARAARAAYGTNAARGTNCARTTYAARAAY--- ---AAYAAYCARCCNMGNGGNYTNATHCARAARAARAGYCCNGGNGTN------AAYGTN AARTTYCARGCNAAYAGYGTNCARMGNAGYTTYGAYGCNMGNTCNAARYTNGGNTCNAAR GCNGTNGTNGAYGCNMGNAAYAARATHGCNTCNAGYAARAARAAYGGNAARGGNGAYGCN MGNAGYAARATHGTNCARAARCARGTNCARMGNGGNACNTTYGAYGCNMGNTCNMGNYTN AARMGNCCNCCN---------------AARAARACNAAYGGNGCNGCNACNAAYYTNCCN GGNCCNCARAAYACNTTYCCNTTYTCNGGNATHCARCCNYTNACNMGNACNYTNCCNAAY CCNATHAGYCAR------------------CCNYTNACNMGNCARATHCCNAAYACNGGN GTNACNTTYTCNAARAAYTCNYTNCARATHACNMGNMGNGGNGGNGGNGGNGGNCCNYTN GTNTCNGCNATGGGNGARGCNGTNCCNATHATHCARATHMGNAAYGAYAARTAYCARGAY ---------MGNCCNGARGTNCCNYTNTCNCARCCNAAYTGGCCNACNCARTCNTCNCAR MGNYTNCCNCARCCNGCNCAYYTNAAYATGCCNTAYCCNGCNCAYAAYAAYTCNCAYACN ------CAYGCNAGYAARCCNTAYCCNTCNCARMGNCAYTAYCARGAYTTYGAYGAYCCN GAYTTYAAY---AARTCNTCNCAYAGYGTNCARGARATHCCNAARATGCAYATHTCNAAY ATHAARGCNGTNGARGCNGCNGGNATGMGNCCNGTNTCNTCNMGNCCNTCNACNTCNCAR ---------------ATGMGNCCNCCNCCNGGNGCNGCNATHYTNTCN------------ ------------GCNAARATGCARGTNTCNATGCCNCCNCCNGGNGCNYTNAARMGN--- GCNYTNCCNATGCARGARGTNGGNGGNCCNYTNMGNYTNGGNAARGGNGGNGGNCCNGGN GTNCARATHGGNATHGGNGARAGYTCNCCNCCNAARMGNGCNAARATHGGNGCNTCNGTN ------ACNAAYCCNATHGARATHATHGARATGAAYGAYAAYTCNAARTAYYTNAGYCCN YTNCARGGNTTYMGNGTNYTNGTNACNAAYYTNTTYGCNMGNGTNACNCARGARGAYATH ATHGARYTNTTYGGNGTNGTNGGNACNYTNAARAARGCNAARYTNYTNAARGCNGGNTCN GCNGARGTNGTNTAYACNTCNMGNGARGAYGCNYTNAARGCNGTNCARAARTAYCAYGGN MGNGARYTNGAYGGNCARCCNATGTAYGTNAARATGACNACNCCNTCNACNGCNACNGTN AARGCNCCNCARGGN---TTYGAYCCNGAYATHACNGGNGARGCNYTNAARYTNTAYAAR AARCCNAGYAGYYTNGGNGCNYTNCCNGTNGCNCCNGTNGARGTNCCNACNATHCAYMGN GCNYTNTTYAARGTNGGNCCNCCNGCNCCNAAYAARTCNGTNAARTTYACNGTNAARATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARAARGGNCCNAAYTGYTCNACNTGYAARGARATHGTNGAYAAYTTYCARAARGGN YTNATHGCNACNGARAARTCNGGNTTYGGNGGNGGNAAYTCNAAYTGGGARGARAARTCN YTNGGNCCNTAYGCNTTYAGYGARGTNMGNYTNGTNGARATHATGGAYAARYTNTGYGCN AGYAARTCNACNGARTGYCAYACNATGYTNGARGARCAYGARGAYYTNGTNGARAAYTTY TGGTTYAARGARTTYGCNAARMGNAGYAARAARGAYTTYYTNACNTTYTTYTGYATHGAR AAYATHAARGCNTGYTGYCCNAAYAAYACNTTYGGNGTNGAYTGYGARCCNTGYCCNGGN GGNATHGAYAAYCCNTGYYTNGGNAAYGGNAARTGYCARGGNGARGGNACNMGNACNGGN TCNGGNAARTGYCARTGYTCNTCNGGNTAYAARGGNGARYTNTGYTCNCARTGYAARGAY GGNTAYTTYCARGAYAGYCARACNGAYTCNMGNGTNATHTGYAARGTNTGYCAYATHTCN TGYAARGGNAARTGYACNGGNGGNGGNCCNGARGCNTGYGARGARTGYAARGAYGGNTGG YTNCARGAYGAYCAYGAYGGNTGYAARGAYATHAAYGARTGYYTNGARGARYTNTGYACN GAYAAYCARTAYTGYACNAAYACNCARGGNTCNTAYACNTGYTTYACNTGYGAYACNTCN TGYGTNTCNTGYACNGGNCCNGGNCCNTAYAARTGYAAYGARTGYACNGARGGNTAYGCN MGNTCNGARAARGGNMGN---TGYGARGAYAARGAYGARTGYCARYTNGAYGCNAGYYTN TGYTCNAARGAYAAYGARGARTGYGTNAAYACNCCNGGNGCNTAYGARTGYATHTGYTCN ACNGGNTAY---GARTAYCARGAYGAYCARTGYGCNAARAGYGCNAARGCNGARAAYGCN GAYACNGCNTCNGARGARGARGCNCARAAYATHGCNGAY---------ATGGGNGGNTCN GARAGYAARMGNAARYTNGTNGTNGARGAYGTNAAYGGNGARGGNGTNGTNCARGTNACN GAR---GCNGTNGTNMGNMGNGTNAARGGNCCNGAYYTNCCNAARGCNACNCCNACNCCN AGYCCNMGNGAYGAYACNAARTTY------------------------------------ ---------AARGARATGAGYAARGAYATHGARGAYTTYTAYAAYGARAARATGAAYGAY YTNCARAARMGNAGYCARGARYTNCARCARCAYTCNAAYGARCARTTYGCNACNGCNGTN AARGARGTNGARCARAARTTYYTNAARTAYACNTCNTCNCCNGTNTGYCARGAYYTNCAR ACNAARGTNYTNGARTGYTAYCARAGYAARGCNGAYMGNATHYTNGAYTGYTCNCCNATH GTNCAYGCNTTYTCNACNTGYGTNGAYMGNGCNMGNACNACNGTNTCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TCNAARGGNGAYGGNYTNAARGTNGAYMGNGTNATGATHTGG AAYGARTAYGARGCNTAYGTNGTNCARTTYAARCARATHGCNGTNTCNGCNTGYGGNCAR ACNGCNGTNYTNAAYGTNYTNAARGCNYTNAARTTYCARTGYGARAARTCNGTNGTNTGY AARGTNATHAARACNAAYYTNMGNMGNGARGAYAARGAYATHCCNGARTAYYTNTTYTCN MGNGCNTGYGCNGGNACNACNGCNGCNGARYTNATGCARGGNATGGARAARYTNACNGGN GGNGTNATHGGNGGNMGNTTYTTYCAYTTYTGGCCNCCNMGNMGNGTNAARYTNYTNCAR TGGYTNGCNTAYTGGATGAARMGNGGNGCNATHCCNYTNGCNACNYTNAAYYTNCARCAR GGNCCNCAYTCNGTNTGGGARGTNCCNGAYTCNTGGCAYCAYCARATGGTNTAYGGNGTN AGYTAYCARGGNYTNTAYYTNACNAAYCCNYTNGARATHGTNTCNGARMGNTCNGCNGTN AARCARYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AGYAGYTGYGAYGAYACNATHGARGARGAYTAYYTNYTNGCNGAYGAYMGNYTNMGN AARCARGTNGAYCARGCNTCNAARTGYGGNTTYTCNGAYAARCARATHTCNAAYGTNYTN AARAARYTNGAYATHAAYTGYAGYATGGAYGAYATGATGAARGGNYTNATHCARCARGAR GAYGAYGAY---CCNGTNATGTGYYTNACNGCNAAYAAYGARGARGARGAYYTNAGYGAY ------------------------------------------------------------ ---------GARTTYGAYGTNGAYGAYAGYAGYAAYYTNMGNGAYATHATHATHGAYGGN AGYAAYGTNGCNATGAGYCAYGGNCARAARGTNTTYTCNTGYAARGGNATHAARATHGCN GTNGAYTGGTTYAARAGYMGNGGNCAYAARAAYATHACNGTNTTYGTNCCNCARTGGMGN AARGARGCNTCNMGNCCNGAYGCNCCNATHTCNGAYCARGARATHYTNACNGARYTNGAR GARGARMGNATHGTNGTNTTYACNCCNTCNMGNMGNGTNGGNGGNACNMGNATHGTNTGY TAYGAYGAYMGNTTYGTNYTNAARYTNGCNGCNYTNACNAAYGGNATHATHGTNTCNAAY GAYGTNTAYMGNGAYYTNGTNMGNGARAGYGAYGCNTTYAARGAYGTNGTNGARNNNMGN YTNYTNATGTAYACNTTYGTNAARGAYACNTTYATGCCNCCNGARGAYCCNYTNGGNMGN CARGGNCCNTCNYTNGAYAAYTTYYTNMGNATHAARCCNGCNGTNCCNAARCAYMGNCCN CARAAYTGYCCNTAYGGNAARAARTGYACNTAYGGNATGAARTGYAARTAYTAYCAYCCN GARMGNMGNCAYACNCCNCARAARATGGTNGCNGARAARYTNAARGARAAYGCNGARYTN MGNYTNAARYTNAGYAARAGYGARGCNYTNGARAARGGNAARGTNTCNAARCCNMGNYTN TCNMGNACNGTNTCNTGGGTNCCNGARGAYAGYCCNYTNTCNCARGTNACNAGYCARGAR GAYCARMGNAARYTNCCNYTNYTNYTNTCNAARTCNYTNGTN------AAY---TAYYTN ACNGARCARMGNYTNAARATGGARCARGCNGARTCNGAR------GARTCNAAYGGNGCN GTNYTNATHAAYAAYATHAARATGCARAAYTCNGAYGTNAAYACNGGNAARATHAAYAAR YTNAAYAGYGAYAGYGCNYTNAGYCCNGGNACNTCNCCNAGYCCNATHGARGTNAARCCN GCNAGYAAYTTYCCNTCNCCNGCNCCNCCNGCNGGNTTYTCNGTNAGYGTNTCNAARGCN GARTCNCARGGNYTNAGYGGNCAYYTNYTNGTNGCNAARAARYTNTCNGAYGARACNAGY CARAAYTTYTTYGCNCARCAYACNTCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGACNMGNGAYGTNTGYACNGAYATGYTNGARACNATHAARCAR YTNAARGARYTNAARTCNGAYAAYCCNAARATHAAYCAYGTNYTNGGNATGCARGARCAR YTNAARGARYTNCARAARTCNYTNTCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGTGGCAYGARGCNMGNMGNCARGARAARAARATHMGNGGNYTNATGGTN GAYYTNAARMGNMGNGCNGAYMGNMGNMGNGARTTYTAYGARAARATHAARCARGAYCCN GCNCARTTYYTNMGNATGTAYGGNMGNCCNGTNAARATHCAYYTNGAYCCNGCNGTNGCN ATGGCNGCNGARGGNCCNCARAGYATGATGGCNTGGCARGGNGAYGARACNAAYATGATH GAYMGNTTYGAYGTNMGNGCNAAYYTNGAYTTYATHTCNGARTAYAAYCCNCAYAARTCN ATHACNGGNAARYTNTCNCAYGTNGARCARGARGARMGNCCNGCNAAYTAYGARMGNTAY MGNACNYTNGTNGARAGYGARGCNGCNGGNYTNTCNGARGARCARTGYYTNCAYCARATH TAYYTNGAYGARCAYTTYGGNACNATHAGYAARACNAAYGARGARGARAARAARAARAAY GCNGAYAARAARGCNGCNATHGGNTTYGTNTAYGARGAYAGYACNCCNGTNGARAARAAR GARGARGARGARAAYAGYGARGARGARAGYGAYGARGAYYTNGAYATGGCNGAYYTNGAY GTNACNATHGAYGTNGAYTCNYTNACNCCNGAYYTNGTNAARGARGTNAAYYTNATHGCN GGNCARTAYGGNATGGTNGAYGAYGAYTTYGTNMGNYTNYTNMGNAARGAYAARGARGAR YTNGARGCNYTNAARGARGCNMGNCARYTNGARGARGCNAARGCNCARTTYTCNGGNMGN AARTCNMGNMGNGARMGNMGNGCNATHAAYGARAARMGNCARAAYCCNCARMGNTTYTGY MGNCCNAGYTAYGCNGCNMGNGAYAGYCCNAARTAYGARCCNTAYAARMGNCCNGGNTCN TCNTCNMGNTCNMGNTCNMGNTCNAARTCN------CCNGARAARACNGARGTNAARTTY ATHACNAGYTTYGGNAAY---GAYAGYGAYGARGAR------GGNGTNGTNCARGGNCCN TCNYTNCCNGCN------GCNGTNGCNAAYCARAARAARATHTCN---------GAYCCN TCNAARTGYGARGCNCCNTGGTCNGTNTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AGYACNMGNGARAGYYTNGGNGTNACN GARGTNCARGARMGNYTNMGNACNAAYCARMGNMGNCARCARGARATHGARMGNCARYTN CARTCNYTNGARGARATHACNCARGARTCNYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GAYTTYTCNCCNAAYCAYAGYGAYAAYAAR GCNYTNGCNGTNGTNATHTAYGAYGARAARAAYYTNTTYCCNCAYCARAARAGYAAYMGN ACNTTYAAYATHGCNGGNCAYAARTTYAAYATHGTNCARGAYTGGCAYGGNGGNGGNGTN GCNGCNGTNGTNTGGGAYGCNGCNGTNGTNYTNGGNGARTAYYTNGCNTCNCAYTCNACN YTNGTNAARGGNAARMGNGTNYTNGARYTNGGNGCNGGNACNGGNYTNGCNGGNATGGTN GCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARYTNGTNACNCAYTTYGGNGGN TGYCAYTGYGGNGCNGTNMGNTAYTCNGTNAARGCNCCNTCNCAYATHGAYATHGTNCAR TGYAAYTGYAGYATHTGYACNAARAARCARAAYCAYCAYTTYATHGTNCCNAARTCNMGN TTYCAYYTNATHCARGGNGARGAYGCNYTNACNACNTAYACNTTYAAYACNCAYGCNGCN AARCAYACNTTYTGYMGNGTNTGYGGNGTNCARAGYTTYTAYTCNCCNMGNTCNAAYCCN GAYGGNTAYGGNATHATGCCNCAYTGYYTNGAYCCNGGNACNGTNAARTCNTCNAARGGN GTNACNTAYGAYGGNAAYCARTGGGARAARGCNTAYGARAGYTCNGAYATHTCNAARTAY TCNMGN------ACNCAYYTNGTNTTYAGYTAYGGNACNYTNAARMGNTCNGARMGNAAY TTYAGYGTNATGAGYACNGCNGGNAARGGNACNTCNAGYTTYGTNGGNAGYGGNGARACN GTNAGYAARTAYCCNYTNGTNGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNGCNAGY TTYGARGAYACNMGNTGYAARTGYGTNTGYTCNCARACNAARGAYTCNTCNGGNAARGAR AARMGNYTNGTNTTYAARAAYACN------AGYGARCARTGYGAYTGYGARCAYGTNGTN AARCCNYTNMGNCCNGAYCARAGYTGYTCNTGGTGYAARTGYCAYTTYGARACNMGNAAY ACNACNACNATHAARGTNGTNGTNGTNTTYGTNATHTGYGTNGTNTCNYTNYTNTTYGTN TAYATGYTNTTYYTNYTNTGYYTNGAYCCNYTNYTNCARMGNMGNCCNGCNAARTCNTAY CARCARCARACNAAYGARGARGAYTAYGARGARGAYYTNTCNTCNMGNCCNGAYGARGAR ---------------ATHGGNCCNTCNGCNTCNCARGGNGCNGARGCNATGACNGCNMGN CARMGNTCNYTNYTNAAYATHGTNACNAARGARCARAARAARTGGAARGGNACNGTNCAR GARCARMGNAARAAYATHTAYGAYMGNCAYTCNATGYTNAAYACNACNTCNTCNTCNTCN TCNACNCCNTCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARGAYTAYTCNATHTGYYTNTCNTGGAGYTAYCARGARGTNATGGARGTNGTN CAYGGNTAYCARTGYGTNATHGGNATHYTNGCNGGNCAYGARCAYGCNGGNCAYCARCAY YTNGAYGARAAYGGNGTNCARCAYATHGCNTTYCARGGNGTNATHGARACNAARCCNGGN AGYAAYGCNTAYGCNACNGCNTAYYTNTTYAAYGAYAARYTNACNATHACNGGNGTNGGN MGNGTNCCNAGYTTYACNATHCCNYTNAARTAYYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GCNATHAGYGTNTCNYTNYTNAARCAYTTYCARCARATGCARTCNGTNTGYYTN GAYATHTCNTCNTCNGCNTGYGARYTNACNCARGCNAAYGCNGARGCNGTNGGNGTNTCN GAYMGNYTNCAYGTNATHCAYGGNGAYTTYACNACNACNAARGTNYTNGARATGGCNGAR GCNMGNGGNCCNTTYTGYTTYYTNGTNAGYAAYCCNCCNTAYGTNACNMGNGCNGARATG GARGTNYTNGCNCCNGARATHACNMGNTAYGARGAYTGYMGNGCNYTNGAYGGNGGNATG GAYGGNYTNGAYATHGTNMGNCAYATHYTNMGNCARTCNGCNCARYTNGTNGTNCCNGAR GGNCAYGTNGTNATGGARGTNGGNGARAARCARCCNGAYYTNATHMGNGCNGAYGTNAGY CARATHTTY---AGYAGYACNYTNCARTAYAARGARACNMGNAARGAYATGTTYGAYAAR GAYMGNTTYTGYCAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGTTYAARAAR ACNAARCCNAARGTNACNCARAAYGGNAGYMGNGARTCNGTNGAYAGYCARYTNAGYAAY TCNACNACNAGYAAYGARAAYYTNTCNCCNAAYGCNAARGAYAAYAARGAYACNGTNGAY AARATHYTNCAYCARMGNGTNCAYTTYCARGTNTAYTAYYTNGGNYTNGTNCCNGARATH AAYYTNACNCAYTCNAARAARMGNGAYACNGARGCNCARYTNATHGAYATHGTNGARGAR AGYCARATHGAYGARAARYTNCARGTNACNGCNACNGARGARAAYAARGTNGTNATGAAY GTNTCNMGNCAYGGNATHAARGTNYTNGAYATHGCNGGNAARGARGTNYTNCARMGNCAY CCNYTNCAYACNATHGCNCARYTNACNGARTAYAGYGAYGGNTTYGGNMGNCARAAYATH GCNGTNAARATHGGNCARGTNGGNAARAAYGTNAAYCARTGYTAYGTNTTYCARTGYCAY TCNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYAARAAYTGGYTNACNTAYATGYTN ATHGCNGTNGTNGTNGTNTGYATHYTNYTNCARYTNAAYTAYYTNAAYAARGCNYTNGAY ACNTTYAAYACNGCNGTNGTNACNCCNATHTAYTAYGTNTTYTTYACNTCNACNGTNATH GTNGGNTCNGCNATHYTNTTYAARGARTTYTTYAARATGGAYATHYTNAAYATHATHGGN GAYYTNTGYGGNTTYTTYATHATHATHATHGGNATHTTYYTNYTNAAYGCNTTYAARGAY ATG--------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------GTNGTNATHATHGTN AGYTTYGTNATHATGGCNGCNTTYGTNYTNGTNAARTAYGCNTGYCAYATGTCNATHAAR TGGAGYGARGARMGNAGYGARGARMGNAGYGAYMGN------------------------ ------GAYAARATHACNYTNGCNMGNMGNGARAARCARATHGARTAYGGNAARAAYACN GAYTCNTAYMGNYTNTAYATHTCNACNGTNCCNAARAAYGARMGNGGNGTNGAYMGNATH AARCAYCCNMGNACNCCNYTNAARTGGMGNAARTGYAGYMGNMGNACNTGGGAYAAYCAR GTNAARGAYTGGAARMGNMGNATHCAYCARTGGGCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNGARTCNGTNTGYCAYGARGTNGTNATGTCN GAYATHGCNATHCCNCCNCCNATHAARACNGARGAYGTNCCNYTNCCNCCNGGNAARCCN TCNGTNAARACNACNAAYGAYAAR---CARGAYATHGCNAARGTNGARGAYYTNACNGAY ATHYTNYTNCCNGARAARCCNYTNGTNGTNGAYGAYAARAGYGTNAARGARGCNGCNGAR CARGTNAARAGYAGYGTNAGYTTYTCNTTYAAYAARACNACNAAYAARATHGCNATHACN TCNGCNTTYATHCARGARGARCCNGAYCCNGTNGARYTNCCNCCNTCNMGNCCNYTNACN YTNYTNGAYAGYATHGARGARGARAARAARYTNATGAAY--------------------- ---CARGARTCNGARGARAARACNGARGCNTCNAGYGARACNAARCCNCARGTNACNAAR CCN------------------------------CCNMGNYTNYTNGARGAYTTYGTNCAR GTNTCNYTNATGAARGARGGNGCNGGNGARATHCCNTGGCCNGCNGARACNATHAARTAY ACNAGYACNCARCCNAGYATHCAYTTYGCNTGYAAYCCNATGCARTTYGAYTTYAARGAY ATGATGAARAAYGCNGGNGCN------GCNGCNGCNGCNGGNCCNGAYACNAARGAYGTN YTNAARGCNGAYAGYGCNGGNAARGTNCCNGCNGARAARATHGAYAARGARGCNAARGAY AARAARAARCAY---TCNMGNAARAARMGNAARMGNAARAARGGNAAYAARATHGARGGN GAYGTNAARGTNGARAARGARGARGGNGARGAYAAR---GGNAARGARAAYACNTCNGCN GTNAARGARGGNGAYGAYAARAGYGARAARAARAARAARMGNAARAARAARAARAARGGN AARMGNMGNAARGCNAARAARGARGGNGARGTNGGNGARGAYACNGCNAARGARGAYGCN GGNGARAARACNGARGAYAAYAARAAYMGNAARMGNGCNYTNMGNAARMGNACNCAYAAR GARMGN---------------GAYGGNGARAARGAY---GARAAYACNGARGGNACNAAR GARGARCARAAYGCNGGNACNGTNGTNAAYGGNAARAARMGNTCNACNCAYAARCAYACN AARAARCAYAARMGNAARCAYMGNMGNMGNMGNCCNGGNCAYCCNGCNAARGGNAARGCN GCNACN------------GCNTCNGARAARGTNAARGTNGAYGCNGGNAAYGCNAAYGAR CCNAARGTNAARATHGAYTAYGAYGARGARGARGAYGTNCAYATHCCNACNGAYAAYGAR CARGAY---ACNGGNGARCCNAARATHAARMGNCCNTGYMGNTCNMGNAARMGNCAYMGN MGNAGYGGNAGYCAYAARGARAAYCCNGARAARAGYATHATHAARACNGAYGAYCARAGY TCNGAYCARYTNAAYATHACNTTYAARACNCAYAARAARATGCARGARAAYATHCCNGAY YTNCCNGAYYTNAGYAARGGNYTNAAYAARTCNYTNYTN---------------CCNAGY AARGARAAYGARAGYCARCARGGNAARACNCCNAAYGGNGAYATHGCNGGNYTNMGNAAR MGNGGNGCNAGYTGYTCNAGYGTNGARGGNAAYACNCCNGCNAARGTNACNAARGTNGAR AARGTNGARGCNACNGARGAYACNTGGAGYAARATGGARGGNYTNTAYGARGARAARGAR GARGARGGNTCNAARAGYAARTGGGAYACNAGYGAYAGYGAYGGNGARGAYGTNYTNCAR AARACNYTN---------------------------GAYGCNAAYGCNAAYGARGARAAY ---AARGCNAARYTNAGYAAYGGNAARATHCCNYTNGCNAARTCNYTNYTNGCNACNAAY GGNYTN------------------------------AAYACNATGAARYTNCARGTNYTN CCNGCNAGYAAYTCNAARGCNGAYGCNGCNGAYACNGGNAARACNGTNAARAGYGAY--- ---GARGTNGAYCARMGNGAYAAYAARTCNGARTCNMGNAARTCNCARMGNGARGGNMGN TCNMGNAARAARACNAGYMGNMGNTCNTAYAGYTCNTCNGARTAYTCNTCNCAYTCNMGN TCNTAYTCNMGNTCNMGNTCNGGNTCNTAYMGNAGYTAYTCNGAYGAYTCNMGNTAYAGY GAYTCNAGYMGNTCNCAYAGYMGNTCNTCNMGNAGYTAYACNMGNAGYMGNTCNMGNCAY MGNTAYMGNMGNMGNTCNTCNTCNAGYMGNGGNMGNAGYMGNAGYTAYAGYTAYAGYAGY MGNAGYAGYTCNAGYMGNTTYCAYTCNMGNTCNTAYTCNMGNTCNMGNAGYTAYAGYMGN TCNMGNTCNMGNACNMGNACNTAYCAYAGYACN---TCNMGNAGYCCN---GCNMGNMGN AGYACNAAYYTNAARMGNATHYTNAARTCNCCNYTNTCNATHGTNCCNGTNACNAAYATH ACNGTNGCNCCNGTNACNGTNTGYACN--------------------------------- ------AGYACNAAYAGYAAYTCNACNTCNGCNCCNCCNGAYGAYATHCCNYTNCCNGGN AARGARGCNCCNACNGCNACNTCNTCNTCNACNTCNAGYCCNCARAARGARGARAARGCN GTNYTNACNGAYATHCCNYTNCCNTCNACNTCNGARAARTCNTCNACNGTNTCNGARAAY AAYTCNGARGCNGGNGGNGAYYTNGCNGCNCCNGGNACNTCNACNGCNGTNGTNCCNAGY ACNGCNGAYGCNACNTCNAGYCARYTNCCNAAYGAYGTNGARAAYCCNGCNGTNGARAGY GTNGCNGAYAGYGTN------------------------------------AGYGAYCCN TCNATGYTNGGN------------------------------------------------ ---TAYGAY---CARGAYTAYAAYCAYATGGGNTAYGCNAAYCAYGAYTCNGCNTTYTGY GARGAYACNGGNTAYGAYAGYTTYGARTTYGAYGGNTCNGGNAGYTAYGAYCAR------ ---CARGGNTAYGAYGAYCARGAR---TAYGAYTAYAAYCCNGAYCCNTAYCAYCAYCCN CCNYTNMGNCAYCARGGNCCNCCNYTNGGNCAYCCNATGMGNGGNCCNCCNCCNCCNGGN TAYMGNGGNCCNCAYCCNMGNATGTTYCAYCCNGAYCCNMGNTTYGGNCCNCCNMGNCCN GGNATGGGNCCNMGN------------------ATGMGNATGGGNCCNCAYYTNCCNATG GGNCCNMGNGGNATGMGNCCNCCNATGGGNCCNGGNGGNCCNATGGGNCCNCCNGGNATG MGNGGN---CCNCCNMGNGGN---CAYATHMGNGGNCCNCCNGGNATGMGNGGNATHCCN GGNATGCCNGGNYTNMGNGGN---CCNCCNMGNCCNGGNATGATGGGNCCNGGN------ GGNYTNATGGGNCCNAAYGGNCCNMGNCCNMGNATGGGNCAYCCNCCNAAYMGNATGGGN CCNCCNATGCARGGNCARGGN------------CCNGCN------------TCNMGNAAY MGNYTNCCNCCNCCNGGNTCNATGGCNGGNCAYATGCCNMGNGAYGGNCAYTTYCCNCCN CARMGNCCNGGNATG---CCNCCNATGMGNGGNCCNATGCCNAAYCARATGMGNGGNCCN GTN---CCNAAYYTNAGYCARCCNCCNCCNAAYTTYAGYATGCCNCCNCCN--------- ---------GCNTCNACNTCNACNGAYGGNAAYAARGCNGGNGAYTCNYTNGARCCNCCN CCNYTNCCNCCNCCNAARCCNCCNACNCCNCARCCNCCNCCNCCNCCNAARAARGARGAR GARAARAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TTYTCNGCNGAYGGNGGNGTNYTNCARMGNGARAAYTCNGAYGTN GCNYTNATHGTNGGNAARGAYGCNGTNYTNAGYGGNAAYTAYGTNACNATHAGYGGNGCN ATHTTYACNGAYGCNACNGTNATHMGNAARAARTTYGAYYTNCCNTCNAAYGARATGYTN ATHACNCCNYTNGTNGARTAYCAYGCNGARGGNTCNTAYCARTTYCAYCARCAYGTNTCN GTNAARYTNCCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNACNGCNATGGGNTTYACNGTNATHCARGCNYTNGGNGARGCNGARAAR ACNTGYGCNTTYYTNAAYATHTCNAARATHGTNGAYGGNTGYYTNACNATHGAYGGNGAY GTNYTNGCNTAYGGNGCNCAYACNGTNGTNATHAARGAYTTYAARGCNTCNAGYAAR--- ---ATGGTNTAYAARTAYGAYAGYTCNGARATHGARGARAARYTNGGNATGGGNCARAAR GARATGGTNGCNGCNGCNYTNYTNACNMGNTGYGAYTTYAGYAAYGGNGTNCCNYTNGTN GGNGARAARACNTTYYTNAARYTNATHAARGARYTNAARGARAAYGGNGTNCCNGAYGTN YTNYTNMGNYTNMGNTCNTGGMGNAAYGAY---------AGYTCNYTNGARGARYTNGAR AARMGNGTNGTNGARGCNTCNGARTCNAARCAYTGYAGYAAYTGYCAYCAYCCNGGNGAY ATHYTNAARCAYTCNMGNTCNGGNTGYGARATHTGYCARACNGAYACNGGNTGYAGY--- ------------AARCARAARATHGAYGAYCCNTGYTGYACNTGYACNTGYCAYTAYCAY AGYYTNGARAAYGARYTNAARCCNCAYYTNACNGARYTNAARGTNMGNAARAGYGCNYTN GARATHTCNCARTTYCCNGAYGARAARGTNATHAARGARTTYYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGGAY GGNGARAARATHTCNMGNYTNMGNGARGARCARCARAARGCNATHTCNGARACNGARGAR MGNATHMGNCARTTYGARAARTTYAARTCNGAYTAYAARGCNYTNCARAARMGNYTNAAR ACNYTNCCNGAYAARYTNTCNCAYGAYGTNATGGTNCCNTTYGGNAARYTNGCNTTYATG CCNGGNAARATHGTNCAYACNAAYGARATHYTNGTNYTNYTNGGNGAYAAYTGGTTYGTN GARMGNTCNGCNAARCARGCNTGYGAYATHACNAGYMGNMGNYTNTCNGARYTNGAYCAR MGNATHAARGAYYTNGARGARCARAARGGNYTNYTNGARCCNMGNYTNGGNATHACNTCN GARYTNCARTCNCARGTNGARGGNAARGGNGAYTAYCARGARATHGTNGARGARTAYGAY GARGARAARGARMGNYTNTGGGAYGARCARCAYAARGTNAAYGTNMGNMGNTAYCARGAR CARYTNMGNAARGARAARGARGCNACNGGNGARCCNAGYGTNTCNAAYAARGARAAYAAR GAYAGYGGNACNGARGARGAYYTNTGGTCNMGNYTNGAYGCNYTNGARMGNCARGARGAR GARMGNGAYGARYTNGAYAGYGAYGARAAYAARGARAARAARAGYACNGGNGCNGCNGAR GARAARGARAARGCNYTNAAYYTNAARGARMGNMGNGTNAGYTGGTTYGAYGAR------ ------------------------------MGNAARAARAGYGCNGAYGAYGARAAYAAY GTNATHGAYAGYGAYGAYAGYCAYGGNGAYGARGAYCARGAYGAYGGNGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GAYTGYTCNGGNMGNAAYYTNATH AARGTNCCNCARAAYYTNCCNTCNTGGYTNATHACNYTNGTNYTNTCNCAYAAYTGYATH TCNGARYTNATGYTNTCNCCNTTYAARMGNTAYCCNAAYYTNMGNTCNYTNGTNATGGAY GGNAAYGTNATHACNAAYYTNCCNGAYCAYTCNTTYCARGGNYTNTCNCARYTNACNGAY YTNATHYTNTCNAAYAAYAGYATHMGNATGGAYCARAARYTNAAYCARTCNAARGCNTTY ACNCCNYTNACNTCNYTNAARACNYTNATHTTYAAYATGAAYAAYAARTAYCCNACNYTN TCNGGNYTNGTNTAYCCNGAYATGGCNYTNTCNTAYYTNACNAGYYTNGARGARYTNCAY ATHGAYGGNYTNYTNAAYAARACNTTYGGNTAYCAYTTYAARAARATGAARAARYTNMGN ACNYTNCARATGTCNGGNTAYAARACNGGNTAYTGYAAYYTNACNTAYYTNTCNAAYGCN ACNTTYACNAAYGTNCCNAAYATHACNYTNYTNAAYATHTCNGAYTGYMGNGTNCARAAR GAYACNGCNGARATHGCNGTNYTNGARCCNYTNATHAARYTNGARACNYTNGAYGTNTCN TAYAAYTTYTAYYTNGGNYTNGARGGNATGGGNAAYYTNATGTAYGGNCARMGNTAYAAY MGNAAYYTNAARATHYTNAARATGAAYATHATHGTNGARMGNTAYGGNCCNTGYGTNGTN YTNTAYMGNAAYACNYTNMGNTAYTTYGTNAAYACNYTNGARATHATHGARGCNTTYCAY AAYAAYATHGARATGATHGARTAYGGNGCNYTNAGYYTNYTNCCNACNACNYTNAARACN GTNTAYYTNAARMGNAAYAARATHATGTTYGGNTCNTAYTGGYTNAAYYTNAAYGARATG ATHCARYTNCARACNYTNAGYYTNGAYGGNTAYGAYGAYGCNTAYAARYTNCCNGTNTAY ATHCCN------------CCNAARCAYATHCAYTGYGGNCAYAAYTCNMGNTCNYTNTCN MGNTAYYTNGCNATHAAYGARGAYGAYGAYCCNTTYYTNYTNCCNCCNAAYYTNGARTAY ATGTCNGTNGARAGYTAYTCNYTNTCNTAYGARATHAAYAARYTNGARTTYGGNCCNATH AAYAARYTNAARGARYTNAGYYTNMGNAARAAYTAYTTYCCNAARYTNACNGGNCCNGTN TAYGGNYTNAAYGAYYTNAARTCNYTNGAYYTNTCNTTYTGYTCNGTNAAYGTNATHGCN CCNAAYTTYTTYTCNTAYTTYAARTCNATHAARACNYTNAAYYTNTAYGGNAAYGCNYTN GGNGAYAGYYTNAGYAARGAYACNAARGGNGGNGCNTTYGCNTCN---AGYAGYYTNGAR GARYTNAAYYTNGGNMGNAAYAAYATHTAYGCNYTNAARAARGGNGTNTTYMGNGGNTGY TCNAAYYTNAARACNYTNAAYYTNACNGAYAAYMGNYTNCAYGAYATHTCNATHTCNCCN GARAAYYTNCCNGARYTNACNACNYTNGAYYTNAGYAARAAYCARATGAGYGTNYTNCAR GCNYTNTGGGAYCAYTTYACNTCNTCNAARAARGTNACNATHGAYYTNACNTTYAAYCCN ATHGCNTGYGAYTGYGARAGYGTNCCNTTYYTNAARTGGGCNACNAARAAYAARGTNTTY GGNGAYAAYCAYMGNCAYTAYTTYTGYTAYGAYAGYTCNTAYMGNCCNATHGARAGYTAY GAYGAYGARYTNAARYTNYTNATGTCNCARTGYGCNGAYAAYGTNCCNYTNTTYATHTGY GTNATHTCNGCNACNGTNGTNTTYTTYYTNGCNYTNATHGGNGTNGTNGTNTAYMGNTTY MGNTGGAARATGMGNTAYTGG--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYYTNACNTCNATHAGYMGNGAYACNCCNTTYTGGGAYMGN CAYTTYAARGGNAARACNGARGTNACNTGGGTNGARTTYMGNGAYAARTTYYTNGCNGAY TAYGGNCARAARATHGTNGARGGNTTYGGNGARTAYGARGARGAYMGNAARAAYYTNTTY ATHAAYYTNATGTAYMGNGAYGTNTTYGAYCAYTCNAARATHATHMGNCAYTCNGTNTAY GARAARTTYTGYGGNAARATGCAYCCNCAYGCNTTYTTYACNGGNATGCARGAYTAYATG ATGGCNTAYTCNTCNYTNMGNGARGTNYTNAGYATGGAYAGYAGYYTNMGNATHTCNACN ATHCARAAYYTNGGNAGYTTYCARTTYCCNGCNATHGTNGCNGGNYTNTCNGARATGYTN GARGAYGARGAYCCNAAYATHMGNGCNGTNGCNACNATHGCNYTNGCNCAYGCNGGNAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHGAR GAYATHGARCARAARATHAAYGTNTGYGARAARMGNYTNGAYGARATHGARMGNAARGGN MGNYTNGTNGARATGTCNGAYGARGARTGGCARGAYYTNAARAAYGARAARAARGCNYTN AAYAARCARGTNAARAAYTAYAARACNGARYTNAARGGNYTNMGNTGGCARAAYTGGAAR ACNACNATHATHTCNATHTGYYTNTTYGGNACNYTNTAY--------------------- ------------GTNAARGTNTCNGARAARAARATGGAYATH---GTNCCNAGYCCNAAY YTNYTNAAYACNCCNTTYGCNTCNAGYCCNCAYTCNTTYTCNATHTAYGARCARGARAAR CARAAY------------ACNTTYTGGGCNGAYCCNAARATHAARAAYGTNGAYATGAGY AGYYTNACNACNGARGARGGNGAYCCNYTNGAYGAYCAYTTYGARGAYAGYTCNYTNAAR AAYTTYTTYTCNCCNGARYTNYTNAAYTCNGTNGCNTCNTCNTCNGGN---GTNCCNCCN ACNTAYGTNTGGGARAAYAARTAYAAYTCNGTNGARTCNCARGGNCCNTCNTCNGAY--- ------------CCNTCNTTYAAYCARYTNGGNGTNGAYCCNGARYTNTTYATHTCNGAY YTNTTYYTNAAYATHGAYTCNAAYGAYAGYAARTTYCCNGCNTTYGAYTTYGARATGAAR TCNGTNCCNAGYAAY---CCNTCNTCN---------------------TCNTGYCARACN CCNGTNCCNTCNGAYTCNAARTCNGAYYTNACNGARYTNTCNGCNGCNAARGAYAAYATH TCNCCNTTYAAYAARGARYTNTCNAAYAAR------GARAGYATHGGNGCNGGNTTYYTN AAYAARAAYTTYTCNATGAARACNAAYTTYCCNCCNMGNAARTCNCARCCNCCNATHGGN ATHGTNTCNCCNGTNAARATHCARGAR---------------GAYGCNAARTTYAGYAAY TTY------------------------------------------------------GGN GAYATHAARATGGAR---------------ATGAARGAYYTNAARAGYGARAAYMGNATH GAYYTNACNGARYTNCCNCCNCARACNGTNCCNTCNTTYGGNGTNACNAAYCARGAYGGN AAYTCNYTNAAYGTNAARCARGARCCNTCNTCNCCNGAR---TTYAAYCARGGNYTNCAY AARMGNTCNTCNTAYGAY---GCNTGGGARGAYTTYAGYCAYTTYACNAAYACN------ ---------------AARMGNAARMGNTAYGAYTCNGGNAGYTCNGGNCARYTNTCNGAY GAR---GGNGAYGARGAR------------GAYAAYGAYTTYAAYGAYGAYAGYGAYGAY GAYAAYTCNGAYYTNGAYGCNGAYYTNGCNCAYATGAARCCNGGNGGNTGYGARTCNYTN ATHGGNGGNGGNAARAARCARAARCARTAYTTYTGGCARTAYAAYGTNCARGCNAARGGN CCNAARGGNACNMGNYTNAARYTNGCNGTNGARGCNCCNACNGAYCCNCAYGTNYTNAAY AGYTTYGARGAYCCNGTNTTYGAYGARGGNAAYACNATGYTNGCNGGNATHMGNCAYGGN GGNAARGCNMGNAARGGNGAYGGNAAYGARGTNACNCCNAAYCCNCARAARYTNTTYMGN ATHGGNCAYCARYTNYTNMGNYTNAAYMGNAARATHAAYGCNTGYCARYTNGGNTCNGAY ATHCCNYTNGARAARMGNAAYGARTCNMGNAARGARNNNAAYAARYTNGCNTCNMGNGCN TGYMGNYTNAARAARAARGCNCARCAYGARGCNCAYAARATHAARYTNAAYGGNYTNGAR ATGGARCAYAGYCARATHAAYAAYGTNYTNMGNYTNATHTGGCCNGARYTNMGNGARAAR GCNAARAARTTYNNNAAYCARCARMGNGTNTGYGARCARTCN---------ACNGARGAR ATHAAYYTNACNTCNAARYTNACNGAYTAYATHTCNTCNAAYYTNAARAGYATGGTNGCN GGNAAYACNACNGAYTAYGTNAAYAAYGTNATHYTNGCNGTNGARCARGGNGAYGTNAGY GGNGGNYTN------MGNAARACNAARAARACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TTYMGNGAYYTNGTNAARCAYGARACNGAYGGNYTNAAYGTNYTN TGYAAYAAYTGGAAYGAYTAYYTNACNAAYGARCCNCARYTNGARGARAAYGTNCARGGN CARATHMGNTGYGCNGTNGGNAARGCNYTNYTNYTNATHGARCARMGNTTYAARCARTTY TCNGGNYTNGTNGAYAAYTAYGTNTAYGAYYTNGGNGARAARAARACNACNTCNTCNGAY YTNCARGGNTTYTGGGAYATGATHTTYTTYCARGTNGARGAYGTNAAYTCNYTNTTYAAR GARYTNGAYGARATGMGNGAYTCNAAYTGGCAYACNGGNAAYAAYTCNGTN--------- ---------AARGCNGARGCNGTNYTNAARYTNAARCCNAARGCNAARGGNAAYACNAAR AARGTNAARTCNAAYTTYGCNGCNTTYMGNGCNGARATGATGAARAARAARGCNCARGCN GCNGCNTCNYTNCCN---GAYGAYYTNAARAARATGAARGTNCCNGARYTNMGNCARACN YTNAARGARAARGGNYTNTCNACNGTNGGNACNAARCCNGARYTNATHAARMGNYTNCAY GARGCNGAYAARACNCCN------GARAGYMGNGAYCCNGTNYTNGAYGAY--------- ------GAYGARATHYTNAARGAYGAYCCNTGYCCNCCNACNGTNGCNCCNTCNTCNTTY TCNACNCCNTCNTCN---------------------------GARAARYTNGCNAARGAR GARATHYTNAGYCCNGARTCNAARTCNAAYGCNCARGTNGCNGAYACN------------ ---------------------ACNGCNGTNCCNAARCCNGTNGARGTNAARAARATGACN GARGARGARMGNATHAARYTNMGNGCNGARAARTTYGGNYTNAAYTCNGARAARNNNAAR AARGARYTNMGNGCNCARMGNTTYGGNYTNGCNTCNGTNGARAAYAARATHGGNACNATH AGYACNTCNAAYGTNACNATHGAYCCNGARAARYTNAARCARMGNGCNGARMGNTTYGGN ------GTNTCNACNACNACNAGYACNGTNATGGAYGAYGARAARAARMGNAARMGNGCN GARMGNTTYGGNGCNACNTCNTCNGTNTCNAGY---------AGYATHAGYYTNAAYTCN ACNGAYAGYGAYYTNGARGCNAARAARMGNAARMGNGCNGARMGNTTYGGNYTNTCN--- GTNGARTGYAARTGGMGNCAYTGYAGYYTNGAYCCNAGYGAYYTNYTNGAYCAYGTNMGN AARCAYGCNGARGGNCARGTNTCNMGNAARAARTAYGCNTGYYTNTGGACNGAYTGYAAR GTNTAYGAYCARCCNGCNYTNTCNGGNTCNTGGYTNGARMGNCAYGTNGTNAGYCAYAGY GGNCARMGN--------------------------------------------------- ------------------------------------------------------------ ------------ACNYTNAARGTNAAYMGNGCNGTNGTNTTYATHGAYAAYAARGTNGCN GARACNYTNCAYTGGATHGGNGGNATHAARACNYTNYTNGAYGCNGGNGCNGARGAYGTN MGNGARTTYTCNTCNTTYGARAGYGGNAAYGARAGYCARAARAARGGNGTNTTYYTNGTN AGYAAYATGYTNGARGGNGTNACNGARCARGTNYTNCAYGAYTGYATHACNCARAGYCAY TTYCARTAYGTNATHGTNATHACNACNGCNCAYCCNYTNYTNCAYCCNAAYATHTCNGCN TCNAGYGTNGARGGNAGYTCNCCNTTYGCNGCNTTYGARGARCARYTNCARGARTGGATG GGNAAYATGAAYTTYACNGCNGARGTNAARCAYATGAGYYTNTTYGGNTGYGARATGTCN CCNGGNTTYTTYATHACNCCNGCNTTYTCNCARYTNTTYCCNYTNYTNTCNTCNGAYYTN CARCARATHAGYTAYCARTAY---GGNYTNAARCAYGGNAARGARGCNATGGCNTGYGAR AGYYTNAAYGAYYTNGAYATHTCNCAYYTNCCNGGNGGNYTNCARAARCARATHMGNYTN TTYGCNAGYGGNYTNCAYGGNATGTTYCARTCNATGGCNGTNAARGARGAYATHTAYTCN GTNGGNTGYYTNAGYMGNATHATHGCNACNGARYTNGAYAGYTTYCCNCCNGCNAARGCN MGNMGNAARGCNTGYCARTCNMGNYTNTCNYTNGTNYTNGTNGAYMGNACNYTNGAYACN GCNTCNGCNGTNACNMGNCARGGNGARGCNYTNYTNGAYAARATGGTNAAYACNYTNCCN AGYYTNCCNGGNCAYAGYACNGAYMGNCARGTNGAYATGGCNCCNYTNTGYCAYTGY--- ---TAYAGYTCNAARCARTCNCARGTNYTNCCNGGNTGYYTNGCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGYTNAARGCN GCNYTNAARACNAGYGAYTGGATHAARYTNGAYACNTGGGARTGYGARCARAGYTGYTGG TCNGARACNATHAARGTNYTNMGNCAYATGAARCARATGYTNGARACNYTNCAY------ GGNCCNAARCCNTCNCCNAAYAARMGNMGNMGNAARCARCARGTNTCNGAYYTNGAYCAR AAYAARYTNCCNAARATGGARACNGARGARGAYCARGTNCCNGCNATHAARTTYYTNTGY GGNGCNGAYYTNYTNGARTCNTTYGCNGTNCCNGGNYTNTGGAARGAYGARGAYATHGAR CARATHGTNGGNTGYCAYGGNYTNGTNGTNATHAAYMGNGARGGNTCNGAYGCNGCNAAR TTYATHTAYGARTCNGAYGTNYTNTCNAARTAYAARGARAAYATHTTYYTNATHACNGAR TGGYTNCAYTGYGAYATHAGYTCNACNAARATHMGNMGNGCNATHMGNMGNGGNGARAGY ATHAARTAYGTNGTNCARGAYTCNGTNATHGAYTAYATHAARCAYCAYCAYYTNTAYGGN TTYCCNGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNYTNYTNYTNTGYAARGCNGAYGCNYTN GTNTCNACNTCNGCNATHAAYGAYCARGCNGTNAGYTGYYTNCARCARGCNATHGAYATH YTNYTNGCNTCNAARGCNGGNACNAAYCAYCARTCNTCNYTNYTNCARTCNCCNGCNTCN AARMGNCARMGNATHAGYTCNGAYGGNGCNGCNATHAGYTCNCARATHCARTCNGARTCN GCNGGNGTNACNTCNACNAAYAAYYTN---TGGTCNGCNYTNYTNGTNGAYACNGCNYTN MGNATGGCNAARGCNTCNTTYGARMGNAARMGNTTYTCNTCNGTNYTNAAYAGYTGYMGN YTNATHACNCARYTNGTNTCNGARAAYYTNAAYGCNYTNTAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TGYGARGGNAARATH YTNGTNGTNGGNGAYGGNGAYTTYTCNTTYACNGTNGCNATGGTNAARTAYTGYGAYGTN GCNAARGAYCARGTNTTYACNTCNAAYYTNGARACNGAYGARACNATHYTNCAYCAYGCN GGNGCNTCNCARAAYATGACNTGYYTNCARGAYTCNGGNGTNYTNGTNTTYYTNGGNACN GAYGCNMGNGAYYTNCAYAAYCAYCCNGTNATHGGNAARGARAARTTYGAYMGNATHATH TTYAAYTTYCCNYTNGCNGAYMGNCAYAAYATHAARAARAAYMGNTCNYTNYTNGCNGAY TTYTTYTCNAGYTGYAARTCNGTNYTNGCNGCNCARGGNCARATHYTNGTNACNYTNTGY AARGGNCARGGNGGNACNCCNGCNGAYCARCCNGTNMGNTCNTGGCAYGAYAGYTGGCAR ATHGTNGCNATGGCNACNAAYGCNAGYTTYYTNYTNCAYAARGTNTTYCCNTTYGAYCCN TCNGAYTTYCCNGARTAYAAYAGYGTNGGNTTYMGNTTYCARGAYAARAGYTTYAAYYTN GTNGGNGCNGTNACNCAYATHTTYGARGARGGNGARACNYTNGARGAYTGGGAYCARAAY GTNMGNGGNGTNGCNGTNMGNGAYGAYGARACNTAYTCNTGYTCNAGYTAYGTNGCNTCN TGYYTNMGNMGNAAYTTYYTNYTNGARCCNMGNAAYCCNGTNTAYATHYTNAAYGARATH YTNGARCAYCARTGGAARGAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TGYYTNGTNAARGTNMGNYTNGTNTTYTCNGTNATHGGNGTNATHGTNGGNYTNTCN GCNGGNTCNGTNTTYAGYTTYCAYTTYAARAAYTAYAAYGCNGGNATGTGGGGNTTYTGY TCNGGNATHGCNGCNAGYGTNGCNATGACNGTNGTNATHYTNTAYATHCARGGNAARTGG GAYTCNAAYCCNYTNCCNYTNMGNGGNYTNATGYTNGTNGGNTGYTTYATHCARYTNGCN GGNGTNTGYGGNTTYGTNGCNTAYYTNGTNYTNGCNATHTAYGARAAYCARGARYTNACN GCNTAYGGNAAYGGNTTYTAYATHGCNTGYGTNTGGTGYTTYATGACNTGGAARTGGGGN TTYYTNYTNYTNATHTAYTCNMGNAGYTAYTTYTAYTCNTAYATGGGNCARTCNGAYCCN ACNTCNTAYTCNGARCCNGARAARTGYGCNATGAARAARYTNCAYYTNAAYGTNAARATH GAYTTYAAYTCNCAYACNGTNGGNGGNGTNGCNAGYYTNTAYTTYGARAARAARGARGCN YTN---GAYGARYTNTTYYTNGAYGCNMGNGGNYTNCARATHGARAGYGTNACNYTNCAR GARGARAAYGTNAGYYTNAGYTTYACNATHGAYAAYCCNTGYAAYGTNGAYTTYGGNGAY MGNYTNTGYATHCARYTNCCNAARGTNCARAGYAARAAYTTYACNGTNGAYATHGARTAY MGNACNTCNCARAAYTCNACNGCNYTNGAYTGGYTNACNCCNCARCARACNGCNGGNAAR MGNCAYCCNTAYGTNTAYAGYCARTGYCARGCNATHCAYGCNMGNAGYYTNTAYCCNTGY CARGAYACNCCNGCNGTNMGNTTYACNTAYACNGCNCARGTNGARGCNCCNAARGARATH ACNGTNYTNATGAGYGCNAAYMGNGGNGARGTNGTNGCNGCNGARGGNAGYCCNGGNCAY AAYGTNACNAGYTTYTCNCARGAYATHCCNATHCCNAGYTAYYTNYTNGCNATHGTNGCN GGNGAYYTNGARTCNMGNGAYATHGGNCCNMGNTCNAARGTNTGGTGYGARMGNGARTCN GTNGAYGCNGCNGCNTTYGARTTYGCNGARACNGARTCNATGYTNCARGCNGCNGARGAY YTNATGGGNCCNTAYGTNTGGGGNCARTAYGAYYTNYTNGTNYTNCCNCCNTCNTTYCCN TAYGGNGGNATGGARAAYCCNTGYYTNACNTTYGTNACNCCNACNYTNYTNGCNGGNGAY MGNTCNYTNGTNGGNGTNGTNGCNCAYGARATHTCNCAYAGYTGGACNGGNAAYYTNGTN ACNAAYGCNAAYTTYGARCAYTTYTGGYTNAAYGARGGNCAYACNGTNTTYTTYGARMGN AARATHYTNGGNMGNYTNTAYGGNGARCCN---MGNMGNCARYTNCAYGCNCAYAGYGGN TGGYTNGARYTNACNAAYAARATHGAYGARATGATGGGNMGNGGNGARGCNGCNTAYACN AARYTNGTNCCNGARYTNGTNGGNGTNGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNMGNTTYGCNACNGAY YTNCARGCNMGNGARAARGARATHGCNTCNGTNAARGTNTCNTCNCCNTCNTCNCCNAAR GCNCARCARATGAAYGAYAARMGNGTNMGNMGNGARATHGCNAAYGGNAAYGARMGNMGN MGNATGCARTGYATHAAYGCNGGNTTYACNTCNYTNMGNGCNYTNATHCCNCAYYTNGAR GGNGARAARYTNAGYAARGCNGCNATHYTNCARCARAGYATHGAYTAYATHAGYAGYYTN GARAARGARAARACNMGNATGCARATGCARYTNGARCARACNACNMGNYTNYTNACNGAR YTNGGNCARCARGAYMGNGTNATGGTNGAYCCNTAYTGYCCNAGYACNCCNCCNCCNTCN AARMGNAARAARMGNGAYACNGARTCNTCNGAYGARGGNGTNGGNTCNYTNTCNGAYGCN TCNGAYGAYAAYAGYACNGAYYTNMGNCARAARAAYGARGCNYTNAARCAYCARATGGAR MGNGARCARAAYMGNGCNGARTCNYTNGARGARGARAAYAARAGYYTNMGNAAYYTNATH TAYYTNATHCARAARCARAGYGCNAARGARCARCARCCNATHACNYTNGTNACNACNGCN ---CAYCARGARGCNMGNYTNMGNGARGTNGTNGARTCNATGTCNCCNCARYTNAAYTAY ACNCCNAGYATGCCNGCNCAYCCNGTNTCNCCNGAYCAYACNATHGCNATGGTNACNAGY ACNGCNCCNCARATGAAYAAYMGNATHYTNGARCCNGTNACNGTNGTNGARYTNMGNGAY GCNCCNTCNACNCAYYTNGCNATGTCNAGYAAYATHACNACNTCNGCNCCNACNCCNGCN CAYAAYTAYGCNCAYMGNGAYCAYCCNMGNMGNMGNCAYCAR---ATGGAYAAYCAYGAR GARATHYTNGAYGCNYTNACNGCNTTYGGNAARACNCCNAAYATHCARGARATHCCNTCN ATHYTNGARCARTAYYTNAAYTGYGTNGCNAARAAYGGNGARACNYTNTTYCCNTGGTCN CARYTNAARCCNYTNGTNYTNMGNAARATGGARYTNGTNATHTCNGAYYTNMGNCARAGY YTNGCNTCNGARAAYATHCCNCCNMGNCCNAAYGTNGARAAYGTNMGNTTYGAYGTNATH CAYGCNMGNATHATHGAYTCNYTNCAYAARTTYAAYGGNGCNCCNTTYACNATHCARMGN ATHTGYGARYTNYTNAAYGAYCCNAARMGNCAYTAYAARMGNAGYGAYAARTTYATGMGN GGNYTNGARAARAAYGTNYTNGTNGTNAGYACNGTNGAYCCNTTYGGNMGNAARGTNGTN TGYGARTCNGGNAAYAARCCNATGGTNAAYGGN---ATHCCNGAYATHAAYGGNGCNTCN TAYCCNTCNMGNGAYTCNGGNYTNAGYATHCCNYTNCCNCCNGTNCCNGGNTGGGTNACN ACNAGYGCNGCNGCNACNACNGCNTCNMGNCCNGGNYTNAGYCARTCNCCNCCNGAY--- CCNAARGCNGAYTCNGGNTCNAGYGTNGARAAYACNCAYGGNGARAGYAAYGGNGTNCCN GGNGGNATGGCNGTNTCNAGYTCNGTNTTYACNGARCAYGGNGGNGAYCCNYTNGCNGTN CAYTCNGARGARGTNGTNGARGARACNGTNGTNACNATGGAYACNAGYGARGTNAGYTCN GTNGTNACNGAYGGNGGNGARGCNATGGCNGARACNGARACNGGNGARGGNGARGGNGAY GTNGCNGARGAYMGNGARGCNTCNTCNYTNTCNTCNTCNTCNTCNTCNTCNGARGARYTN TCNACNTCNGARACNAGYACNAARGCNTCNCCNTTYMGNGTNACNGTNCAYAAYTTYAGY GTNGARGARYTNGAYGARAAYMGNCCNTGGGCNGCNTTYGCNCARGAY------------ ------------------------GCNAARGCNCARGGNGAYGCNACNTCNAAYCCNTCN TCNGAYAAYCCNCCNGGNGGNCARCARYTNGARGGNACNCARTTYTCNGARGCNTCNTCN TCNTCNYTNCARATGTCNAARTCNCCNGARGCNGCNTCNTCNTCNTCNGTN--------- ------------------------------------------------TCNTCNTCNTCN TCNCCNGCNCCNTCNGAYACNCARCARACNTCNTCNTCNYTNATGTCNGAYCCNTCNAAY CARCARACNGAYTCNAARTCNGCNGAYAGYCARAGYGTNGAYGARGCNTCNTCNTCNCCN YTNYTNGCNGCNAAYGARATHAGYGCNACNACNAAYCARAAYYTNGCNACNTCNTCNGGN CCNGAYCARACNCCNACNACNATGGAYGTNACNGARGARGAYAARCARGCNTCN---TCN TCNACNAGYATGACNGTNAGYACNTCNGAYACNGARAGYTCNTCNTCNGGNTCNCAYGAR CCN------------------------------------TGYTCNTCN------TCNTCN CCNTCNYTNMGNAGYTAYGCNCARGTNGTNGCNTCNTCNACNGAY---CCNGCNCCNTCN ATGCARGTNGAYGTNCARTAYGARTCNGTNGCNGGNAGYGTNCCNTGYGAYAGYGTNGCN GGNYTNGARMGNYTNGTNGGNTCNATGGARCARTCNYTNGCNGCNTCNCCNTCNTCNTGY TCNTCNTCNTCNCCNGTNAGYACNTCNTCNTCNTCNTCNACN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ACNCARGTNGCNGCNAAYMGNAARMGN AARYTNGCNCARTCNATGGCNCCNGAYAAYATGMGNYTNTAYGAYTTYYTNCCNAARAAR AARGGNAARGCNAGYYTNTCNAARGCNAARATGAAYATHGAYTCNTTYAARAAYAARTCN GARCCNTCNYTNAGYAARCCNGARTCNATHGAYGTNAARAARTAYGTNAARYTNCCNGAY ACNCCNATHGCNAGYGGNATGATHTTYGTNGARGARCAYACNATGGARMGNGAYCCNAGY CARGARCAYCAYATGATGGCNCARATHACNATHTAYCARCCNCARYTNGGNGAYMGNTAY CAYGGNGARTTYTAYYTNGAYCAYGAYTAYAAYCAYAAYMGNTCNGGNAARGARGGNMGN MGNTGYAGYTTYGTNATHGGNTCNMGNCAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TCNACNTCNTCNACNCARGCNCAR TCNAAY------------TCNCCNTCNACNTCNGCNTCNAAYGAYAARAARMGNAARAGY ACNYTNTCNGAYGARGARYTNAARCARGCNATHAARMGNTTYAARAARCARGAYGARGAR MGNATGMGNATGCARGTNYTNGTNTCNAAYTTYTCNGARGARCARYTNAAYMGNTAYGAR ATGTTYMGNMGNGCNACNTTYCCNMGNGCNGCNATHAARMGNYTNATGCARAAYATHACN GGNACNACNGTNTCNCARAAYGTNGTNATHGCNATGTCNGGNATHTCNAARGTNTTYGTN GGNGARGTNYTNGARACNGCNYTNGAYGTNAGYGARAARTGGGARGAYTCNGGNGCNYTN CARCCNAARCAYYTNMGNGARGCNGTNMGNATHYTNAAYGCNAARGGNATGATGCCNACN ACNAARAGYAARAARAGYYTNTTY------------------------GTNCARGTNCCN AGYGCNAAYAARYTNGGNGCNYTNCCNGCNAARATGAGYGGNGAYCCNACNAARATGACN MGNGGNYTNATHGTNYTNCARGARTGGTGGGGNATGAAYGARCARATHCARACNTGYGGN AARGAYYTNAGYCARGGN------AAYYTNGTNACNYTNGTNCCNGAYYTNTAYMGNGGN AARGTNACNACNGAYAAYGARGARGCNGGNCAYTTYATGGGNGAYYTNGAYTGGAARGGN GCNGTNGAYGAYATHCARGGNGCNGCNMGNTAYYTNAARAGYAARGGNGTNAARAARGTN GCNGTNGCNGGNTTYTGYATGGGNGGNGCNYTNTCNATGGCNGCNGCNGCNYTNGTNCCN GARGTNGAYGCNGCNGTNCCNTTYTAYGGNATHCCNGGNGCNGAYYTNTGYGAYGTNACN ACNATHAARATHCCNGTNCARTGYCAYTTYGCNYTNCAYGAYGCNACNGCNGGNTTYGCN TCNCCNGCNGARTGGAARCCNYTNAARGCNAARYTNGARGCNAAYYTNAARACNYTNGAR TTYCAYGARTAYGAYGCNGGNCAYGCNTTYACNAAYAARACNGGNGAYAAYTAYAARAAR GAYYTNTGYGAYCARGCNTTYTCNMGNATGTTYCARTTYYTNGAYAARCAYATGTCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNACNAARGTNTCNACN GAYGARYTNAGYAAYGTNTGYCAYGTNGTNGCNGAYAGYTTYTGYCARGAYAARGCNGTN AARTCNGAYCARYTNGTNTCNGCNTGGTCNYTNGARGARTGGTGGGARGTNMGNGCNGCN YTNYTNGCNGTNATGAARAARGCNGCNCARYTNGAYTTYAGYAARGAYCARATHAGYACN GARYTNGGNTCNYTNGGNGARTCNTAYAARTCNGTNATHACNGARGCNATHAGYGTNCAR MGNGCNGCNYTNAARCAYAARYTNYTNCARAGYACNACNGCNATHTCNCAYGCNGTNYTN TCNGAYTTYGAYTGGAARYTNCARYTNGCNYTNTCNAGYGAYAARATGTCNAGYYTNCAY CARCCNYTNYTNTCNYTNGAYYTNGAYATHMGNCARGCNGAYGGNGARATGMGNCARGTN GTNYTNGARATGAAYAARGARGARYTNGCNMGNYTNATHTCNTCNYTNGARAAYTGYAGY AARACNGGNGCNAGYYTNATHGAYGAYGTNYTNAARGARGTNYTNGARTTYGCNGTNMGN GAYTAYATHAARACNTGGTAYMGNCARAARAGYGAYCAYGAYGARTTYYTNAARGAYATH TGGCARTGYGCNCARAARGTNGTNATHACNTTYGCNAAYMGNTCNAARGARATHGARTGG ACNCCNTAYTTYACNCAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CAYGGNGGNCAYGGNGAYCAYGAYTCNGGNAARCCNYTNGARTTYGCNTCNGAR ATHCAYAAYAARGAYCAYATHYTNGARCAYYTNTCNAAYGTNATHGCNACNAARTCNAAR GARCARYTNACNGAYGARGARYTNGARTTYCAYTAYTTYAARYTNCAYGAYTAYGAYAAY AAYAAYAARYTNGAYGGNGTNGARATHGGNAARGCNYTNACNCAYTTYCAYGAYGGNGGN GAYGAYAARTCNACNGARCCNAGYGGNACNAARAAYCCNAARGCNGARTCNACNTCNGAY GAR---GTNYTNAGYTCNACNATHGAYATGGTNYTNACNMGNTTYGAYACNAAYMGNGAY GGNTAYATHGARTAYTTYGARTAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGAYATHGTN GTNGTNGGNAGYTGYATGACNGAYYTNGTNAGYTAYGCNTCNCAYYTNCCNAARGARGGN GARACNYTNACNGGNTAYAARTTYGCNGTNGGNTTYGGNGGNAARGGNGCNAAYCARTGY ATHACNGCNGTNMGNYTNGGNGCNATGGTNGCNATGGTNGGNAARYTNGGNGAYGAYGGN TTYGGNCARGARTAYATGAARAAYATGAARACNAAYAAYGTNAAYTGYGAYCAYYTNAAR ATHGCNCCNGGNGTNTCNAAYGGNGTNGCNTCNATHCARGTNGCNGAYAAYGGNGCNAAY TGY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATGTCNTTYCCNGGNMGNACNCCNATG------------ GCNATGCCNGGNATGACNCCNMGNATGATG---ACNCCNGGNTAYGCNTTYACNGCNTCN GGNATGCCNMGNATGAAYCCNATGATGCCNATGCARATGGGNATGATGACNCCNATGATG CARCCNATGATG---CARCCNCARATGCARATGCARCAR---CARCARTCNGTNAARCAR AGYACNAARTTYGTNCCNCARGARATHCCNAARACNGAYGGNAARGGNGARAARCCNCCN GTNACNACNGTNTTYGTNGGNAAYATHAGYGARMGNGCNCCNGAYATGATGATHAARCAR ATGYTNCARMGNTGYGGNAAYGTNYTNAGYTGGAARMGNGTNCARGGNGCNTCNGGNAAR YTNCARGCNTTYGGNTTYTGYGARTAYGARGARCCNGARGCNACNYTNMGNTGYATHMGN YTNYTNAAYGAYTGGCCNATHGCNAGYAARAAYYTNGTNGTNAARGTNGAYGCNAARACN AARACNYTNYTNGAYGARTAYMGNAARAARAARTAYGGNAAYGAYAGYGTNTCNACNAAR AARGARCCNGARAGYGAYGAYAARAARGARAARGGNGARGARGARAAYGGNGARGARAAR GARAARACNGARGAYGTNAARAGYGARGGNGARAARGGNAGY---GARYTNGAYGARAAY ACNAARMGNGARGAYMGNGTNGCNCARGCNGGNYTNGARGCNATHATGMGNGARTAYGCN TTYGARYTNGCNAARGARCCNTCNAARTCNGTNGAY---GGNGAYTCNGAYAARGAYAAR CARATHCCNAARAARGAYAARGAYATGTTYGTNCAYGCNAARGAYACNGGNTTYGAYGAY ATGGARATGGARGAYGARAARMGNGARATHATHAAYMGNGARATHAAYAARTTYMGNGAY MGNCAYAARGAYGAYGAYGARGARAARGARAARGAYGCNAARGARAARGARMGNAGYYTN GCNMGNGARMGNGARMGNMGNCARGARGARAARMGNCARMGNGARAARYTNGARYTNYTN MGNGARCAR------------------------MGNGAYMGNGARMGNGARMGNTCNMGN ACNAARGTNTCNMGNTCNAARTCNMGNTCNGCNTCNCCNGTNATHTCNMGNTCNMGNMGN MGNTCNMGNTCN------------MGNGARMGNACNAGYMGNGAYMGNTCNMGNGARMGN MGNAARGARMGNGARYTNGARGARGARGARGARYTNTTYGARMGNMGNAARYTNGARAAR AARYTNMGNGARAARGARGCNGCNTAYCARGARMGNYTNAARAAYTGGGARGGNMGNGAR MGNAARAARACNMGNGARTAYGARAARGARAAYGARMGNGARGAYGAYMGNAARGTNGAR GARACNMGNGARGGNMGNMGNYTNAARGARTTYYTNGARGAYTAYGAYGAYYTNMGNGAY GAYCCNAARTTYTAYAARGGNAGYGCNYTNCARMGNMGNYTNAARGARMGNGARAARGAR AARGARYTNGAYAAYMGNGAYMGNCARMGNGARAARGARGARTTYGARGARATHAARMGN AARYTNTTYGAYGARGGNCAYCCNGAYGCNGARACNGARGTNGCNMGNATGGARMGNGAR MGNGARGARCAYYTNCARCCNMGNYTNCAYYTNCARGARGTNGARCARCCNCAR------ ------------CARTCNCARTCNGARTCNGCNCARGCNGTNGARGARAAYTCNTAYGAR GARACNTCNAGYMGNGARTCNCCNAARTCNTCNGARTAYTCNCARTCNAARAAYYTNTCN ------------------AAYAAYACNCAYCARCCNCAYYTNACNGCNCCNGAYCARMGN CCNTCNCCNTCNYTNTCNACNTCNCCNATHTCNACNGAYTCNMGNGTN---AGYGCNCCN GGNYTNTGYATGGAYGARTCNTCNCARTCNTCNYTN------GCNACNATGCCNCCNYTN TCNTCNAAYAAR---GARACNAARYTNYTNGCNGTN------------------------ ---------------CCNGGNATGAGYCCNGAYTCNAGYAGYYTNCCNGGNACNGTNAAY GCNTCNGAYGGNAARMGNAARAARYTNACNGTNGGNGAYGTNTTYAAYCARGAYGAYGAY GAYAGYAAYGARCCNAARAARMGNAARYTNATHCCNYTNGAYTAYGAYGAYGARAARTCN TCNCCNACNGARAARAARGGNACNAGYGCNGARGARAARMGNAARAARATHAARCARYTN ATHGARAAYATHCCNACNGCNAARGAYGARYTNTAYGCNTAYACNGTNGAYTGGGARATH GTNGAYCARGTNYTNATGGAYAARMGNATHAARCCNTGGGTNACNAARAARATHGTNGAR TAYATHGGNGARGARGARCCNACNYTNACNGARTTYATHTGYCARAARGTNATHGCNMGN AGYACNCCNCARAGYATHCARAAYGAYGTNGCNATGATHYTNGAYGARGARGCNGARGTN TTYGTNGTNAARATGTGGMGNYTNYTNGTNTAYGARACNGARGCNAARAARYTNGGNYTN GTNAARYTNYTNAARGARGARTAYYTNGCNCAR---TGYAARATHTGGCCNCARTCNGGN CARCAYATHYTNGCNCAYTTYGAYGAYGAYACNGTNGTNGTNTAYCARGCNTAYAARCCN TCNATHGCNGAYTTYGCNGTNAARCAYCARACNTTYGGNGGNGTNGAYTTYAGYTTYGAY MGNATGTCNTGGATHAARACNAAYTTYATGTGGATGATGTAYMGNTGYGGNTGGGCNCAR AARAARTCNCARGAYMGNGTNYTNGCNGTNTGGYTNACNMGNTTYGGNTTYGARGARATH YTNTCNCARGCNAARACN------GGNAARGARGAYAAYAGYATGAARAGYAARGGNGAY CARGTNMGNYTNCARTGGGAYCCNGAYCAYAAYCCNAAYGGNGGN---AARCARACNMGN MGNGCNATHCARYTNGGNYTNMGNGGNATGGGNAAYTGYGTNCAYMGNTGYTTYGGNGTN ATHGAYMGNMGNAARMGNTAYYTNCARTCNAARTAYACNACNGARCARAAYTTYTCNATH GARTTYGARAAYYTNATGGARGARGARCCNCARGAYGARATGTCNMGNYTNYTNACNGAY MGNGARMGNCARYTNYTNAGYTCNAARCARTTYTCNACNYTNGCNYTNGARCARGGNCAR GTNGAYACNGARATHGAYGCNAARYTNAARCAYGARYTNGARMGNGARGARGARGCNTTY TAYGARGCNAARAARGARGCNGCNMGNGTNGCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TGGAARACNCCNAGY GTNCARMGNATGTGGYTNGGNCARCARGAYGGNGAYAARGAYMGNMGNYTNMGNGCNTTY YTNACNATHATGATGAGYGAYACNAGYYTNATGYTNAAYACNAAYTAYATHCCNCARCAY YTNYTNGTNATGTGYTCNGTNYTNMGNTAYATGYTNCARTGYGGNMGNATHYTNCARMGN CCNGARYTNGAYGCNTTYYTNGCNATGTCNGTNTCNCCNYTNYTNMGNGAYATHCARACN ATGCARGAYYTNAARYTNCCNCAYATHATHCCNMGNGGNAGYCARYTNGCNTCNYTNTTY ATGGCNGGNATHGARACNGCNTGYATGGCNAAYGAYGTNTGYGGNGCNCCNATHCCNTGG TCNATGATHTGYCCNTGGYTNTAYATGGAYGGNAARYTNTTYCAYTAYAARYTNYTNAAR GCNAGYAAYAAYACNCCNYTNATHGAYYTNTGYGAYGGNCARATGGARCARGTNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARGAYATGACNGAYGTNYTNMGN CARGCNGARGCNATHMGNCARCAYMGNGAY---------------------AAYAARCCN AGYAARGCNGAYYTNAARGCNAARGCNAARGTNACNAARAARGTNGTNACNAAYGGNGCN ---------------------------------------------------GARTCNTCN AARGARACNYTNCCNAARACNCCNAARTCNCARGCNACNCCNGCNACNCCNATHACNACN AGYACNACNAARATHAAYAGYAGYMGNAARGARGGNATGTTYGGNGGNATGAARAARGGN TTYYTNTTYGGNGGNAARACNTCNCAYCCNAARTCNGCNTCNACNGCNTCNTCNTCNTCN ACNGTNAGYGCNGARMGNTGYAARACNGARTCNAGYCAYACNAGYTCNGGNGAYACNGGN ACNATGAARGAYTCNAARGARGAY---ATHCCNTAYATHAARCCNTCNGGNAARACNGAR TCNGGNYTNAGYTTYGAYGARGTNCARGARGCNATGTCNGARGCNAARGGNYTNYTNGAY AAYCARGAYTGGATHACNAAYGAYYTNYTNACNAARATHGARAARAAYGAYATGYTNYTN AARMGNTTYAGYGAYCCNCAYTTYATGGCNGCNYTNCARGARTTYCARAAYAAYCCNCAR GCNGCNATGGARAARTAYAARGGNGAYGTNGARGTNGARAARTTYYTNYTNGARTTYTGY GGNYTNYTNGGNGAYCAYTTYACNAAYYTNGAYAGYAGY--------------------- ---AGYAGYAGYAAYAGYGCNAARACNCARCARGCNAGYCARAGYAARGCNTCNAAYAAR ACNYTNCCNYTNTCNGCNCARCARCCNAAYGCNATGCCNCCNCCNGTNGCNMGNGGNCCN AARATHGTNGARYTNGARCCNGAYGAYTGYGCNGGNCARGGNGGNAARGAYCARCAYTCN GGNAAYGCNATHGTNGAYYTNGGN------------------------------------ ------------GCNGGNGGNGARMGNGGNAGYMGNCARAARGGNCARTCNGAYATHMGN ATHCAYGAYAAYAGYAARGGNACNGAYATHCARGARGTNCCN---------------GCN GCNGCNGAYGARGCNGTNMGNMGNGCNYTNAGYGAYCCNAARGTNATGGAYACNYTNATG GAYCCNGGNGTNATGAAYYTNATHAARACNATGMGNGARGAYCCNGGNAARGGNCARMGN YTNGTNGARAARGCNGGNGAYGAYYTNAARAARAARATHGAYTTYYTNGTNTCNAARGGN YTNYTNAARTTYCARYTNAAYCARAAYAARACNAARCCNTCNAAYGTNCCNTCNYTNYTN YTNGCNGAYTAYGARAAYGARCAYYTNTTYCARGCNYTNGGNATGTAYAGYGTNACNYTN GCNACNGGNGTNGTNCARYTNTAYYTNTCNGAYCARTCNGAYMGNACNMGNTGGAAYAAR MGNTGYTGYGGNGTNGCNTGYTTYGTNMGNGAYAGYTCNAARAARTCNTTYTTYATHAAR GTNTTYGAYATHAARAARGGNCARATHATHTGGGARCARGARYTNTAYAAYCARTTYGTN TAYAARACNCCNMGNGARTAYTTYCAYACNTTYGARGCNCAYAAYTGYCARGCNGGNATG AAYTTYGCNGAYGARGAYGARGCNAAYAARTTYAARAARGCNGTNGAYGGNAARYTNAAY GAYAARYTNAARAARAARCARGAR---AARMGNCARAARTCNGTNCAYCAYGGNCAR--- ------GTNAGYGGNGAYCAYGTNGCNGCNAGYCCNCCNCARMGNATG---GGNCARAAY GCNGCNCCN---------ACNCAYGTNGTNACNGTNGGNTCNAGYGCNTCNTCNTCNGCN AAYCARAARAARGARTCNAARGAYAARAARGGNAARGAYGCNAARAARAARYTNACNAAR GCNGAYATHGGNACNCCNTCNAAYTTYGTNCAYATHAGYCAYGTNGGNTGGGAYCCNGAY AARGGNTTYGAYATGAAYAAYYTNGARCCNGAYATGCARACNYTNTTY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNGTNTGYYTNTTY------------------------------ ------------------------------------------------TTYTCNGCNTCN TGGTGYACNCCNTGYCAR------------------------------------------ ---CAYTTYGTNCCNACNYTNAARGARGTNTAYACNGAYYTNGTNAARMGNAAYAGYCCN ATHGARGTNGTNTTYYTNAGYTTYGAYAARACNGARAARGARATGATGGARTAYTAYAAY AARAARCAYGGNGARTGGYTNGCNGTNAARTTYGGNGAYCCNYTNAARCARGARYTNGCN GARMGNTAYTCNGTNAGYGTNATHCCNMGNYTNATHGTNATHCARCCNGAYGGNGARGTN ATHAGYAGYAARGGNMGNAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TGYGGNYTNATGTTYTAYTGGGARCCNYTNAAYAARTCNGTNMGNATHGARGGN AARGTNGARAARYTNAGYAARGARCAYTCNGARAAYTAYTTYCAYTCNMGNCCNMGNTCN AGYCARATHGGNGCNTGYGTNAGYGARAAR---CARAGYTCNGCNGTNCCNTCNMGNGAR GTNYTNGAYAARMGNAAYGARGARYTNCARGCNAARTAYAARGAYGAYTCNGTNCCNATH CCNAARCCNGAYTAYTGGGGNGGNTTYMGNGTNGTNCCNCAYMGNTTYGARTTYTGGCAR GGNCARACNAAYMGNATHCAYGAYMGNATHGTNTTYMGNMGNYTNCARGARGARGARGCN GTNGAYCCNGCNGTNACNTTYCAYGGNGAYGAYGGNTGGGTNTAYGARMGNYTNCARCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGNTTYAGY YTNACNGGNGAYATHCARTCNGTNACNGARGARGARTTYAARGCNACNATHGARCARYTN GCNAGYAAYGAYMGNTTYMGNMGNAGYGCNCARMGNTTYTCNMGNYTNTTYAARGTNAAY CARGGNYTNCCNGTNGARMGNGCNGCNTTYTGGYTNGAYCAYGTNATGACNTTYGGNGGN GAYTAYATGMGNACNYTNGGNCARCAYATGCCNACNTAYGARTTYTAYGGNYTNGAYYTN YTN------YTNGTNYTNTCNYTNATGGGNTGYACNTTYTGYYTNGTNTGYTAYYTN--- ------------------------------------------------------------ ---------------------------------GAYTCNTTYTCNYTNYTNAARTCNGCN ACNTTYGTNACNGGNGTNGGNACNTGYAGYTTYYTNGGNGCNATGATHTGGAAYTAYGAR MGNGTNMGNAARGTNTAYAARGARATG---TCNGCNGARAARGTNGCNCCNCARAAY--- ---ATHGTNACNGARAARYTNTTYGGNTTYMGNCARCAYATHAAYTCNATHTGGAGYAGY YTNGAYTCNTCNGCNAARYTNACNGGNGCNATHATHYTNGCNAAYATHGTNGTNTGGGGN TTYTGGMGNGTNCCNMGNTTYCARCARMGNATGATGMGNTTYTTYTCNTCNGCNGCNGTN CAYCCNMGNTCNTCNATGGTNYTNAGYAGYTTYAGYCAYATHAGYTTYYTNCAYYTNGCN GTNAAYATGTAYGTNYTNATGTCNTTYGCNCCNGTNGCNATGMGNYTNTTYGGNCCNGAR CARTTYACNGCNTTYTAYATHAGYGCNGGNACNTTYTCNGCNTTYGCNAGYATHGTNTGY CARMGNYTNYTNMGNMGNCCNCCNTCNATHTCNGTNGGNGCNTCNGGNGCNATHATGGGN YTNYTNGGNGTNACNGGNATHGTNTAYCCNAAYGCNMGNYTNCARGTNGCNTTYGTNTCN GARATHGTNCCNCAYTCNTTYTCNGCNGARACNGGNATHAARGCNATHGTNYTNTTYGAY YTNGTNGGNYTNYTNATGGGNTGGMGNGTNYTNGAYCAYGCNGGNCAYYTNGGNGGNATG YTNTTYGGNATHYTNTAYGCNAARTAYGGNAGYAARYTNGTNTGGGGNAAYMGNGARTCN GTNATHAARGTNTGGCAYGAYGTNMGNGGNAARCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GGNGTNCCNAARGTNCCNTCN AARCCNCCNACNACNGTNAARGARTTYAAYYTNCAYAARACNAGYGGNCAYCCNCARMGN YTNYTNAARGAYCARMGNGAR---GARGARATGGTNGARTTYCAYGCNCAYCCNGTNAAY MGNAARATHYTNGARGGNCCNGTNGGNGTNAARCCNGCNGARAARMGNCCNATHACNATH CCNGARTCNCCNGCNTTYGCNYTNMGNGARMGNGTNAARTCNCARGARGARGCNCCNCCN GCNCCNGCNCCNGCNCCNAARGTNACNAGYAARCCNGTNYTNCAYGCNGGNGTNCCNTTY MGNCCNCARYTNGARCAYAARTGYACNATHCCNAARCCNTTYGCNGTNGARGAYCAYAGY AARGARATGYTNAARAARAARGARGARAARATHAARCARGTNYTNGARGARGARMGNAAR GCNMGNGARTTYACNGCNAGYYTNYTNCCNAGYGAYAGYCCNGAYCARYTNCCNGCNMGN AARACNMGNCCNGTNACNACNGTNGARCCNTTYAAYYTNTCNGCNGAYGAYMGNGGNAAR AARTAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR AARGCNCAYATHGAYGAYGTNYTNACNCCNGAYYTNGAYGAYGCNGTNYTNMGNATHGCN MGNATGMGNAARGCNCARGTNGTNAARTGYAARTCNGCNGCNMGNAAYATHGTNACNAAY TCNGTNAARTAYTAYAGYACNGTNACNGTNGARTGYGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TCNGAYGCNGAYAGYGAYYTNAARAGYYTNGAYACNATGGCNYTNYTN ACNGGNAARCAYGARACNMGNCARGTNYTNTCNTCNATHGARCARGAYMGNACNGTNYTN AGYCCNAGYTTYGCNAGYAGY---------------GTNAAYGGNCAYGTNTCNTCNGAY GGNYTNGAYGGNGAYMGNCCNTGGGARAARCARGCNAAYTCNTTYAARCCNCCNGTNCCN GTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ACNATGAAYGGNGAYCAYTCNTCNAAYAGY GTNACNGTNTGYGTNMGNAARYTNGARGAYGAYTCNGCNTTYCCNTAYGCNGGNMGNGAR GGNCARGTNGCNTGYAGYGTNTCNGAYAARGTNTAYGTNTTYGGNGGNGTNGARCARGGN CARGGNGAYGARCCNAARGARACNAAYGARYTNGTNGTNTTYGAYYTNGGNGCNCARAAR TGGTCNAARCCNGCNGTNYTNGGNTCNCCNCCNGCNGCNMGNTCNGCNGCNTCNTTYGTN GCNGTNGGNGARAARYTNTAYYTNTTYGGNGGNYTNAGYCAYATHTGYGGNTGGTTYGAY GAYATHCAYGTNTTYGAYACNGTNAGYAAYACNTGGTCNYTNYTNGAYACNGARGGNGCN AARCCNMGNGCNMGNGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGYTNACNATHACNGAYTTYATHAAYATHYTNAARGARTAYTAYAARTCN CCNAARATGACNATHGARGARYTNGARGAYCAYAARATHTCNACNTGGMGNGAYYTNYTN AARCARAARCARMGNCCNTTYYTNTCNATHTGYCCNGAYGAYAGYYTNTTYGAYGCNGTN AARATGYTNGTNGAYAGYCAYGTNCAYMGNYTNCCNGTNATHGAYGARAAYACNGGNAAY GCNYTNTAYATHATHACNCAYAARMGNATHYTNMGNTTYYTNCAYYTNTAYTTYAARGAY YTNCCNCAYCCNAGYTAYATGAARAARTCNATHAARGARYTNGGNATHGGNACNTAYGAR AAYGTNTTYACNGCNACNCCNGAYATGACNYTNATHAARGTNYTNAAYYTNTTYTCNGAY CAYMGNATHTCNGCNYTNCCNGTNGTNGAYAAYGAYTCNGGNAARATHGTNGGNATHTAY GCNAARTTYGAYGTNATHAAYYTNGCNGCNGARAARACNTAYAAYAAYYTNGAYATHACN YTNCARGARGCNYTNAAYMGNMGN---TTYGAYAAYAGYCARTCNGGNGAYGTNGTNYTN TCNTGYMGNTCNTCNGAYTCNYTNGARGAYGTNGTNAAYAARATHGTNAARGCNGARGTN CAYMGNYTNGTNGTNGTNGAYGARAGYGGNGGNGTNGARGGNATHYTNTCNYTNTCNGAY GTNYTNAAYTAYACNGTNYTNMGNCCNATHGARCARGTNTCN------------------ ------------------------------------------------------------ ------------------------------------------------------ACNGGN GGNTTYTCNGCNGGNTAYTTYAAYACNGTNGGNTCNAARGARGGNTTYACNCCNTCNACN TTYGTNTCNTCNMGNAGYCARAARCAYGAYATHTCNCARACNTTYMGNCCNGARGAYTTY ATGGAYGTNGARGAYYTNGARGARCAYGGNATHGCNCCNMGNAARTTYGCNACNGCNAAR AAYTAYACNTCNGARGARMGNAARMGNAARYTNGARGAYTCNGCNAARAGYATGTCNGCN TCNTTYGCNACNGAYATHGGNAAYGCNYTNAGYGAYYTNATHGTNCCNGARTAYYTNCCN GTNGGNATHAARYTNYTNMGNAARATGGGNTGGMGNGAYGGNCARGGNYTNGGNCCNMGN GTNMGNMGNAARAARAARAARAGYAARGARAAYAARAARCCNGCNGGNAARAARACNTAY GGNTGYGCNYTNCCNCCNTCNGAYCAYGAYGAYACNGAYTCNGAYTCNTTYGTNCCNGCN GAYATGAGYGAYYTNACNTTYGCNCCNTCNGAYGTNACNCCNATHACNYTNTCNGCNAAR GAYGAYGTNAARGGNYTNGGNTAYMGNGGNYTNGAYCCNAGYYTNGCNYTNCCNGGNTCN CAYGTNAAYYTNTTYAGYAAYCCNGTNMGNAAYAARAARACNAGYCARGGNATHMGNGGN CAYGCNTTYGGNGTNGGNGCNYTNGARAAYGARGAYGAYGAYGTNTAYGCNCARGAYAGY YTNGCNAAYTAYGAYATGACNATG---MGNGARGGNGAYAAYCARGAYAAYAAYTTYGGN TGGACNGCNCCNMGNGCNCAYGGNAARCARAARYTNCCNGTNTCNTAYGTNGGNAARYTN YTNGARGGNTTYTGYYTNTCNTCNAARCCNYTNAARCCNAARAARAARTTYCCNACNCCN AGYYTNCCNGCNAAYTTYAARCCNTTYCAYTGGACNMGNMGNMGNAARAARGAR---GAY ACNGCNYTNACNGARGGNAGYMGNAAYCARATGACNGCNGTNGAYMGNGGNYTNATGYTN GGNGARACNCCNATHATGAAYTCNGTNTTYGAYYTNATHAAYAAYCARGAYAARTCNMGN ATHAGYCAYACNCARGARGCNATHGARATGACNAARTCNYTN------------------ ------AARAARTCNCARGARTCNGCNCARGGNYTNCAYACNGGNAAYGARAAYCARGAR GTNAAYGAYAARAAYGTNCCNATHATHCARAGYCCNCAYCCN---AARTTYYTNTCNAAR TTYACNCCNGCNGTNAGYGAYAAYGCNGARACNAAYGTNMGNAGYGCNTCN---ACNGAY CCNAAYAARCCNYTNTTYCARGGNGCNATGAGYYTNCARCCNTTYMGNAARGAYCCNGCN AARCARGCNMGNTAYGAYCARTAYYTNGCNGCNGTNAARGGNMGNGTNTCNGAYCCNTTY GCNGARGTNTCNACNMGNTCNATGACNGARTGGGARMGNGCNAARGARMGNGAYGARTTY AGYMGNTCNGCNAARYTNTTYMGNCCNATGTCNGCNATGATGTCNACNMGNTTYGTNGAR GGNGCNATGYTNGAYGAYAARAAYGARGARGCNAARAARGARGAYAARGARACNCCNTCN GAYGARGTNAARGCNGCNGARATGMGNATGTTYGGNAARYTNACNMGNGARGARTTYGAR TGGCAYCCNGAYAARYTNYTNTGYMGNMGNTTYAAYGTNCCNAAYCCNTAYCCNGARTCN GAYATHGTNGGNYTNCCNTTYGCNAARMGNGAYAARTAYTCNGTNTTYAAYTTYYTNACN ATGGGNGAYTTYMGNCCNAAYGARGCNGCNAAYCCNGARTCNGGNAGYAGYAARGAYGTN TCNCARTCNTCNGARTCNGCNCCNGAYGAYTCNGGNGAYCAYAARCCNTCNAARAARAAR GCNACNYTNTCNTCNATHTTYAARGTNYTNGAYGAYCCNGAYTTYCAYAAR--------- ---YTNCCNGARGARGCNAARAARGAY------------------GTNYTNGARCARGGN ACNGARACNAARGARAARGARGARGAYGARACNGARGARCCNGAYGTNGAYYTNTTYMGN GCNATHTTYAARAAYTCNGAYTCNGARGAYTCNGARGAYGARAARACNGARAGYGARAAR TCNGAYYTNGARAARTCNGAYAARGARGARGARGGNATGAGYGARGAYGGNGAYGAYAAR YTNGGNGARGARAGYAGYGCNAGYCCNMGNYTNTCNACNGTNACNTCNMGNCCNGAYGAR AARGARGCNTTYCARGARGAYYTNAARCARGARGARAGYGGNGARAARGARGARAAYACN CCNGTN------MGNTCNGCNGGNMGNGCNGARYTNGAYAAYCCNTTYGCNAGYGTNGTN MGNGAYCCNGGNATHAARTCNMGNMGNTCNCARACNMGNTGGACNGCNAARTCNATHTTY AGYGTNYTNGAYGARGTN---------------AAYGGNGARGCNTGYAGYCARGAYGAY ---------------------------YTNGARYTNGARTCNTCNTAYGGNCCNGCNYTN CCNCCNGCNGTNGAYCCNGCNCCNACNCCNCAYTCNTCNYTNCCNACNACNGARGARTCN MGNTCNYTNACNATGACNMGN---CAYGARCARGAYGTNAARCAYAARMGNCAYAARCAY MGNAARGARATHAARAARAARTCNAARCAYAARAARGARAARAARMGNAARAARAGYAAR AARTCNTCNTCNAARTCNAARMGNCARACNGCNGAYGGNGCNGGNAGYGAYGCNGAYTCN GARTCNTCNGAYGGNTCN------CAYGARGAYGARYTNGTNGARAARTGGAARCARGTN TCNMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARAARYTNMGNATHGCNTCNTGGGAYTGYTCNCARGARGTNGTN GTNGAYYTNTAYGCNGGNATHGGNTAYTTYACNYTNCCNTAYYTNGTNCAYGCNAAYGCN AGYCAYGTNCAYGCNTGYGARTGGAAYCCNGCNGCNGTNCARGCNYTNMGNAAYAAYYTN GTNYTNAAYGGNGTNGARAGYMGNTGYACNATHCAYCARGGNGAYAAYMGNCARYTNAAY YTNTCNTGYGTNGCNGAYMGNGTNAAYYTNGGNYTNATHCCNAGYAGYGARGAYGGNTGG CCNGTNGCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARGAR YTNAARYTNCARAAYATHCARAARTTYATHGARGGNATHMGNACNGARYTNGTNTCNTGG TGGGAYAARTGYTTYTTYGAYCCNCARGAYMGNAARAAYTTYACNTAYTAYTAYGARGAR AAYTTYACNGARGARYTNYTNGAYGTNCAYGARAARGARYTNGAYAARGTNMGNGARTAY CAYAAYCARCAYMGNGAYATHYTNGARAARYTNACNCARMGNGARGARYTNTTYAARAAY ATGATHYTNTTYGAYGCNAARGCNAGYGAYCCNAARMGNTTYTTYAAYGAYMGNGGNGGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGGARAARACNGTNGAYTCNYTNGARGGNATGTTYMGNAARACN GARAARGAYYTNGAYTTYYTNTCNMGNAARYTNGAYTGYCARYTNGARAAYATGCARGAR GTNGAYCARMGNGTNAAYCCNGTNAARATGATGAARAARATGGARAAYATHAARGCNGAR TAYGCNAAYATHGTNCARGAYGTNYTNGCNGTNCARGARGCNCARAARGARATGTCNGAY TAYTTYMGNTCNCARYTNYTNACNYTNACNGGNYTNYTNGGNAARYTNGARACNGCNACN GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNAAYYTNACNYTNCAYCCNAAYGCNACNCAYTTYGAR YTNGCNGCNACNMGNTCNACNTCNGGNMGNTGGGAYGAYMGNATHAGYGTNAGYATHGCN TTYGTNCAYTTYTGYATHGCNYTNACNTGYTTYYTNGTNMGNTAYGCNTCNGTNTTYTGG TAYACNAAYAARGCNYTNACNYTNGTNTTYGCNTTYCARYTNGTNTCNATGGTNTTYAAY TCNGTNTTYGGNTTYAGYAGYTTYGCNGCNYTNTAYAGYGTNTGYTAYAAYCARAARATH TTYCCNAAYATHCAYYTNTCNATHGGNTGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ACNGAYCARTCNTCNTCNAARYTNGARCARGCNTTY TAYGAYGTNCCNTGYATHGAYYTNGCNMGNAAYYTNYTNGGNCARTAYATHGTNMGNGCN ATHGGNAARCAYAARYTNMGNGGNMGNATHGTNGARACNGARTCNTAYATHGGNCCNATH GAYAARGCNGCNCAYAGYTAYCARGGNAARAARACNCCNAARAAYGARGCNATGTTYATG GCNCCNGGNACNTGYTAYGTNTAYAAYATHTAYGGNATGTAYTGYTGYATGAAYATHTCN AGYCARGGNGAYGGNGCNGCNGTNYTNATHMGNGGNGTNGARCCNGTNGAYGGNCARGAR YTNATG---------GARCARGGNMGNMGNGGNAARGAYCARAAYAARAARCCNYTNAAR GARAARGAYYTNTCNAAYGGNCCNTCNAARYTNTGYCARGCNTTYCARATHTCNAARAAY GGNTTYAAYAARACNGAYYTNACNTCNTCNGAYTCNYTNTGGYTNGARAGYGGNGAYTGY ATHGAYCAYAGYACNATHGTNAGYTGYCCNMGNATHAAYATHGGNTAYGCNGARGAYTGG AARGARAARCCNYTNMGNTTYTAYTGYYTNGGNAAYTCNTGYGTNAGYGTNMGNGAYAAR GARGCNGAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------MGNCCNCARCAYGAYYTNAAYYTNCCNACNGTNGTNAAYGTNACNTTYGAY YTNYTNTCNATHYTNGARATHGAYACNGTNAARCARCARATHGTNGTNAAYGGNATGTTY TGYYTNACNTGGATHGAYGARYTNYTNTCNTGGACNCCNGCNGAYTAYGGNAAYGCNYTN YTNATHCAYCCNGAYGTNAARCARATHTGGMGNCCNMGNGTNATHYTNAGYAAYACNGTN GAYAARMGNGAYYTNTTYGARGAYATHACNAGYCCNYTNTTYGTNCARGCNTCNGGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNTCNTCNCCNTCNCCNMGNAGYAAYTAY GAYGGNMGNCARYTNCCNAGYATHCCNAAYCARGCNGGN---CARGCNTCNMGNCCNAGY AGYTTYMGNTCNTCNAGYTTYAAYAARAAYAGYAARGGNAGYAAYGGNTAYGGNCCNTTY YTNCARGARTAYTCNYTNATGGCNGARTTYAAYCARGTNCAYTAYCARAAYATHCCNGGN YTNTAYACNATGCCNTCNTCNAARTCNCCNYTNGTNTGGTGYGGNYTNATHTTYATHMGN CARGGNYTNTAYCARGGNGCNGCNYTNMGNTTYACNYTNAAYATHCCNCAYAAYTAYCCN GAYGGNGCNTGYCCNAARTTYGTNTTYGARTAYCCNGTNTTYCAYCCNYTNGTNGARCCN GARACNGGNGARYTNGAYGTNAARMGNGCNTTYCCNMGNTGGMGNMGNAAYGTNAAYCAY YTNTGGCARGTNYTNYTNTTYGCNAARAARGTNTTYTAYAAYATHGAYACNAARATGCCN TCNAAYCCNGARGCNGCNGTNYTNTAYGARCARGARCCNGARYTNTTYAARAGYMGNGTN GTNGARTCNGTNGCNGCNGCNAARGAYMGNYTNTAYCARCCNCCNTCNYTNGAYGAYCCN YTNGCNYTNMGNTTYAGYCCNTGGAAYGAYGTNGTNCAYATGGARACNCAYMGNCARATG YTNCARACNTCNAARAARTGYGARGGNGAYAAYTCNTCNGCNAAYCCNTCNGAYYTNGGN YTNTCNTGGATGGAYCCNACNCAYCCNAARATHTTYGCNGCNGAYGAYCARCCN------ ---------------------------YTNGCNTAYCARTCNGTNCAY---------GCN CCNYTNCARGTNCCN--------------------------------------------- ---------AARAARTAYATHGARCCNTAYTCN--------------------------- ---TTYATHCARAAYAARGCNMGNMGNAARTAY---GGNATGGTNTCNGCNATGGAYGAR GGNGTNGGNAAYYTNACNCARGCNYTNAARGARGCNGGNYTNTGGGARAAYACNGTNYTN GTNTTYTCNACNGAYAAYGGNGGNCARGTNCAYGARGGNGGNAAYAAYTTYCCNYTNMGN GGNTGGAARGGNTCNYTNTGGGARGGNGGNTTYCAYGGNGTNAGYTTYGTNACNGGNCCN YTNYTNAARTCNMGNGGNACNGTNAAYAARGARYTNATHCAYGTNTCNGAYTGGTAYCCN ACNYTNGTNAARYTNGCNGGNGGNAGYYTNAAYGGNACNAARCCNYTNGAYGGNTAYAAY CARTGGGAYACNATHAAYYTNGGNGCNCCNAGYAARMGNAARGTNYTNYTNCAYAAYATH GAYATHYTNTAYMGNAARAARGGNCARCARYTNTAYAAYGAYACNTTYGAYACNMGNGTN MGNGCNGCNATHMGNGTNGGNGAYATGAARYTNATHACNGGNGAYCCNGGNCCNGGNTCN TGGATHCCNCCNCCNCAYCAYTCNYTNCAYTTYGTNTCNGARATHGAYAARAAYGTNTGG YTNTTYAAYATHACNGCNGAYCCNACNGARCAYTTYGAYYTNTCNGAYGARATGCCNGAY ACNGTNMGNGGNATGYTNAARCARYTNGARGCNATHAAYAARACNGCNGTNCCNCCNMGN TAYCCNCCNTTYGAYAARAAYAGYAAYCCNGCNYTNCAYGGNGGNGTNTGGGGNCCNTGG ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYCCNGAYATGMGN------------AGYATHATGGARGARYTNATH GAYGARGTNTCNYTNGGNYTNTGYTTYGARATHCAYMGNTCNTGYAARATHGGNTCNTTY TTYYTNGAYGGNTGYGAYGARACNTCNGAYACNGARTAYGCNATHATHGARMGNCAYGGN GTNGAYGTNYTNGGNCARGTNCARTCNAARAARAAYTAYGARTGYGTNTGYCCNAAYTGY CAYMGNCCNYTNGCNGCNTCNMGNTTYGCNCCNCAYYTNGARAARTGYATGGGNATGGGN MGNAAYTCNTCNMGNATHGCNAGYMGNMGNATHGCNAAYAAYCARAARCAYGGNAGYGAY GARAGYGGNCARGARGAYGARAAYGAYAAYGAYTGGAARTAYGCNCCNCARTCNAARMGN YTNMGNAARATGAARMGNGAYAARATGTCNAAYACNCCNMGNAAYMGNMGNYTNGCNAAR YTNMGNAAYAAYMGNAAYGGNACNAGYAGYAAYCAYACNAGYGGNTCNACNGCNCCNCCN GCNGCNGCNACNCCNTCNACNGCNCCNATHTCNACNGCNACNGCNGCNACNGTNTCNGCN TCNTCNATHGTNAGYGCNACNGARYTNCCNGAYACNCARGARCARACNCCNAAYTAYGAR AGYATGAGYYTNGARGARMGNAARGCNYTNYTNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGAARGGNTGYGCNACNAAYMGNCAR TAYGARGAYGTNYTNGARGARATHMGNAARGARYTNTCNMGNMGNCARAAYTAYCAYCAR GARGCNTTYCARMGNCAYCARACNATHYTNAARGAYNNNCAYCCNYTNCAYCCNCAYYTN TGGGAYTTYCAYGTNTCNTAYYTNGAYGAYMGNYTNMGNGGNYTNGTNGAYTCNATH--- CARGCNMGNAAYAARGARGARGCNGARMGNGTNTTYATHCARAAYGGNGGNATHGTNYTN GGNAAYAAYYTNTAYMGNYTNCCNGTNTTYTCNCCNGARTTYTGYGARCARYTNGTNCAR GARYTNTCNCAYTTYGARGAYAGYCCNTGYCCNAARGGNMGNCCNAAYACNATGTCNAAY TCNGGNATHTCNYTNGAYGARATHGGNATHTCNGARGGNYTNYTNTCNCCNYTNATHTCN GARTAYATHCARCCNYTNTCNACNACNYTNYTNAGYGARMGNTGYGAYGGNCARYTNGAY TCNTTYMGNGCNTTYTCNGTNYTNTAYGGNTCNGGNAARGAYACNGARYTNAGYATGCAY TTYGAYAAYGCNGARGTNACNYTNAAYGTNTGYYTNTCNTCNCARTTYCARGGNGGNGAY YTNGARTTYGGNGGNYTNTGGAARGAY------------ATHGCNACNGGNTCNGAYMGN GARACNGTNTCNCAYAARATGGGNATGGGNGTNYTNCAYYTNGGNCARCAYACNCAYMGN GCNYTNCCNATHGTNTCNGGNACNMGNTGYAAYYTNATHGTNTGGATGMGNAGYTCNGCN GTNMGNAAYCARTTYTGYMGNATGTGYGAYTCNAARCCNGAYYTNCARGARGTNCCNTTY GCNGGNGAYGGNTTYACNCARGAYGGNAGYAGYCAYTAYACNTCNAGYACNTGGMGNATG GCNGCNGCNACNGGNGTNATHTAYGGNGGNATHATHTAYGTNAAYMGNTAYCCNAAYMGN MGNMGNATGCCNCCNATHTGYACNAAYAARTAYGAYMGNATHCARAAYAGYMGNGTNTTY GGNAAYTTYATHTGYCCNMGNATGAAYGARACNTCNAGYCARATHTAYTGYTGYGGNMGN AARAAYMGNGARTAYTGYTGYGAYATGGCNACNGCNAARATHTAYTAYGGNAARAAYTCN AARAGYGARAGYTCNYTNTCNATGGGNGCNGTNTTYGGNATHYTNGTNGCNATHGGNGTN GTNATHGCNATHGTNGTNTTYTGYTGYAARMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AGY---TCNAARTTYMGNAAYTTYGARATHCARACNACNTGGGAY GGNATHAGYGTNTGYCAYGARCCNATHCAYATHACNYTNGGNGARACNTCNGAYTCNGAY YTNYTNATHAARGTNAARGCNCCNTTYTTYGAYAGYCCNGCNAARCCNGAYGGNCCNGCN GGNCARCCNTTYCCNAAYYTNTGGGAYTAYGARGTNGTNGARGCNTTYTTYYTNAAYGAY GAYAAYMGNTAYYTNGARGTNGARYTNGGNCCNCAYGGNCARCAYYTNYTNYTNYTNYTN AAYGAYACNMGNAAYATGGTNAARTGGAARYTNCCNATHACNTAYACNGCNTCNATHCAR GGNAARCARTGGACNGGNGARGCNGTNATHCCNMGNAGYTAYYTNCCNCCNGCNGTNACN AARTTYAAYGCNTAYGCNATHCAYGGNGARGGNTCNYTNMGNCARTAYCARGCNYTNTAY CCNGAR---------ACN---------AAYGGNCARCARCCNGAYTTYCAYMGNYTNGAY YTNTTYAARCCNYTNGAYATGACNGCNGTNYTNTCNAAYTAYAAYCCNTCNTTYGTNTCN AGYGARTGGGCNCCNTAYGTNAARTCNAAYGCNCARGCNGARYTNCARCARYTNAARAAY GARMGNGTNMGNYTNYTNGAYYTNCARAGYCARYTNAARCARYTNCARAAYGTNGTNGAR MGNMGNTCNCARGAYCARCARGARTCNGCNGARACNGARMGNGAYAAYGARAARACNGAR ACNGARCARGCNCCNAAYGCNACNGTNGTNACNTTYGCNTCNAAYGAYGARYTNTAYAGY AARATGMGNMGNCARMGNATHYTNCAYGARGARYTNMGNTCNAARAARAARGARYTNGAR GCNATHATGAARAARGAYMGNAAYAARMGNCARTAYTCNMGNAAYCARGAYAAYCARAGY GAYACNGTNTCNYTNAAYACNGAYACNTTYGGNATHCCNGCNAGYGTNGAYGCNGARGAY GARGAYGGNAAYGARGAR------GAYGAYGGNTAYCCNAGYGAYGGNATHGTNCARGTN GARGARGARGARGARGARAAYGAYACNGAYAAYGGNACNTAYACNATHGARGCNGAYGCN MGNCARMGNAARAAYATGMGNAARCCNGCNCAY---GGNATHGGNGCNMGNCCNAARACN GCNMGNGGNMGNCARACNTTYCCNCARCCNGCNTAYTCNGAYCARTCNTCNAARMGNYTN GGNAARAAR---AARMGNCAYATHCARAGYAARCARMGNGAYTCNAARATHMGNCARGAR AAYTAYMGNTCNGCNGARGARYTNATHCARGARGAYGARGGNAARGGNMGNAAYTCNGAR TGGTTYMGNYTNATGGARAAYMGNYTNGAYAAYYTNAGYTCNTCNGTNGAYYTNYTNGTN AARAARYTNGAYTCNGGNGGNMGNCARYTNAGYGTNTCNYTNAGYCARGARAAYACNTCN CCNCCNATGCARGARCARATGYTNCARYTNCARAAYCARTCNATGATGYTNAGYTTYAGY CAYGTNGTNCARTCNYTNTCNMGNCARCARGGNGAYATGCARCARYTNCARTCNAGYTAY TCNAGYATHCARTCNATHAARGAYGARCAYYTNMGNATHAARCARGARCARCARGGNGTN AARTCNTCNAAYGARGARGARTCNAAYACNYTNTTYGAYAGYYTNMGNGAYACNATHTAY ACNGARGTNGCNTCNYTNATHTCNCARAAYGARAAYMGNCCNCAYTTYCARCCNAARYTN GGNGARGGNGCNTTYYTNGCNTCNGARCARYTNYTNYTNGCNAARGGNTCNAARYTNMGN GGNGCNAGYGCNAARCCNAARMGNAGYYTNGARGARGARTAYGGNGARGGNGCNAGYAAY TCNGGNGTNGAYCARGCNAGYGARAGYTCNYTNTCNGAYATGCCNTAYCCNMGNATHGAY ATGAARCARYTNGAYYTNCARATHAARCARGTNATGATGGARACNATHCCNGTNGTNAAR GARCAYATGGARGAYATHTGYTCNAGYCARYTNYTNGCNTAYATHAARMGNYTNGTNYTN TCNYTNACNACNCARACNGGNAGYCARGARTTYGCNMGNTTYTTYCAYMGNCARYTNTCN TCNATGYTNCARGAYACNYTNGARAARTAYGARGGNMGNAARATGMGNGARTGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CCN AAYTTYYTNGGNTCNATGACNYTNAARGCNYTNYTNGARGAYCCNAAYYTNAARAAYCCN CCNYTNATHGGNCARTCNAGYCARATHTCNAARGTNAARAARGAR---AARGGNTCNGAY YTNCCNCARTAYAAYTAYGGNTCNGCNTTYYTNGGNCCNGCNYTNTGGGAYAARTCNTAY ACN---GAYYTNAAYYTNGARTAYATGGAYYTNGAYGARTTYYTNTCNGARAAYAAYATH CCNATHACNGARGAYGAYGGNYTNGCNGGN------ATHACNYTNGAYCARGARGAYGAR AGYTCNCARCARNNNNNNGGNAAYCARACNCCNGAYGCNGTN---GTNAGYTCNCCNMGN CARTTYYTNMGNACNCCNCCNYTNAGYCCNTCNCARTAYYTNGARAGYTCNGCNCCNGCN ACNCCNTCNTCNTTYCCNACNGTN---------CCNATHAARGTNTCNTCNTCNCCNTCN CCNCCNGGNAGYCCN---TTYAARGTNGAYTTYCARGTNTCNGARCARGAYYTNGCNYTN ACNGCNGTNCCNGAYTAYAARGAYGCN---AAYTAYCCNAAYGCNCARGGNTGGATHCAR ATGGGNGAYGAYCARAARCCNAARYTNGGN------GTNTCNTTYGAYCCNMGNAARMGN AAYTTYACNGARGARGARYTNAARCCNCARCCNATHATHAARAARTCNAARAARGTNTTY GTNCCNGARGAYYTNAARGAYGAYAARTAYTGGGCNMGNMGNGTNAARAAYAAYTAYGCN GCNAARMGNTCNMGNGAYGCNMGNMGNGTNAARGARAAYCARATHGCNYTNMGNGCNGCN TAYYTNGARAARGARAAYAARTGYYTNMGNGARGARATGTCNAARYTNMGNAARGARAAY GCNAARYTNAARACNATHGCNGAYAARTAYGARCCNGGNAARGGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CCNGGNCCNTAYTCNGARGAYGTNTGGCCNCCN CARGARGGNTCNCARYTNAGYMGNGCNGCNATGYTNACNCAYTAYACNATHAARTTYTGG CARTAYACNMGNMGNGARCARTAYMGNCCNYTNAARGAYAAYAARGGNMGNCCNYTNTGY ATGTTYCARTTYMGNMGNGTNTTYAAYGGNTGYMGNATHCCNGGNGTNTCNMGNGAYAAR YTNYTNCARTAYTTYAARACNGARTCNGARGGNCCNTGYCCNTCNCAYYTNATHGTNATG TCNAARGGNCAYYTNTTYGCNYTNAAYACNYTNGAYGARTCNGGNGARGTNYTNACNCCN CCNGARATHGARAGYCARYTNCAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TAYAARGARAAYGARATHATHACNATHACNTGYATHGCNCARGGNCCNTCNAAYYTN MGNTTYTTYTGGGAYMGNAGYTGYCCNACNGARTTYAAYCCNAAYCCNGCNTTYGTNAAY TGGCCNGTNGCNAAYGAYATHAGYGARYTNAGYAARGARAAYGGNGARGCNAAYACNTGY GAYGAYAAYMGNTAYAGYCARTCNYTNACNTTYAAYATGACNGCNGAYYTNCAYAARTGY CARATHMGNTGYCARTTYGGNTCNAGYCARTTYGCNAGYAAYAARATHCAR------GGN AAYATHACNGTNAAYYTNGAYGAYGARGGNGGNAAYGGNGGNAAYGGNGGNACNCCNGGN TCNAGYGCNGAYAAYACNGGNYTNATHGTNGGNYTNGTNATHGGNYTNYTNGTNGTNYTN ATHATHGTNGCNGTNGTNYTNATHTAYGTNTGYTGGTAYMGNAARMGN---GAYGCNCCN AAYAARTAYAARGAYGAYCAYGAYACNGARGCNAAYCCN------AAYACNCAYGTNCCN CCNCCNGTNGTNTAYTCNAARCCNAAYAARCARCCNAARGARGAYGTNGAY--------- ------GGNATHTAYATHCCNGGNCARGGNCCNTAYACNAAYTAYCCNACNCCNGGNGCN CARCAYGTNYTNCCNCCNACNGGNCAYTAYACNCAR------GCNCCNCCNCARGCNTAY GCNATGGTNTCNACNCCNGGN------GGNCAYCCNGCNTAYACNCCNAGYTAYTCNTCN ATGCCNTAYGCNGCNAGYYTNCCNMGNYTNCCNAAYTCNTCNCCNGCNTAYATHCCNGTN TCNCARTAYCCNGCNGGNATGGGNTAYCARACNGCNACNATGGCNGGNMGNTCNGGNCCN CCNCCNGGNAGYYTNTCNGCN---CCNYTNCARACNGGNGCNCCNYTNTTYGCNGCNGGN TAYACNCARYTNCCNGCNGGNATGTCNACNCCNGGNGCNGCNMGNTCNYTNCCNATGGGN CCNGTNGCNACNTAYCCNCCNGGNTAYGGNTAYCAYGCNAAYGCNGCNGCN--------- ------------------YTNATHYTNCARACNGGNGGNACNATHGAYAARMGNTAYCCN CARGGNCCNGGNGCNTAYGCNTTYGARTTYGGNGARCCNGCNGTNGARAARATHYTNMGN CAYATHMGNCCNAGYTTYCARTAYMGNGTNGARAARGTNTGYGCNAARGAYAGYCARGAY ATHACNGAYTAYGAYMGNGARGAYATGYTNMGNGCNATHGTNGARTGGGAYCAYCARAAR GTNYTNATHACNCAYGGNACNGAYACNYTNTGYGAYACNGCNCAYTAYYTNTGYAARGCN GGNGTNGGNCARGGNGTNCARCARGARCCNGGNGTNGGNGGNAARACNGTNATHYTNACN GGNGCNTTYYTNCCNYTNACNATGAARGARTCNGAYGCNGAYTTYAAYGTNGGNTTYGCN YTNGGNTGYYTN---TAYTCNTCNCCNCCNGGNGTNTTYGTNGCNATHGARGGNAAYGTN YTNGAYGGNAAYCAYGCNATHMGNCAYAARAGYGGNAARTTYGTNGAYAARMGNCAYGTN GAYATGGARTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNGGNGAYGTNAARMGNGCNTTYGAYAAYGAYGTNACNCCNTTY TTYGCNYTNTTYATHTGYTGYTGGGGNACNGTNTTYYTNGARATGTGGAARMGNCARTGY GCNACNYTNGCNTAYGARTGGGAYGTNGAYCARTTYGARGCNAAYGARCCNGAYMGNCCN CARTTYTAYGGNACNMGNGTNAARCCNGAYCCNGTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGTCNGARAARCAYGAYTTYGGNGTNGCNCCNATHTCNTGYCAYGCNTTYGAYAARGAY MGNAAYGGNYTNGCNATGTCNYTNAAYGAYTCNAAYGTNAARATHTAYAARAARTCNGGN GCNAARTGGGAYGARGTNGAYACNYTNAGYGARCAYGCNCARMGNGTNACNAGYATHGAY TGGGCNCCNAAYAGYAAYMGNATHGTNACNTGYTCNGCNGAYMGNAAYGCNTTYGTNTGG ATGYTNGARGAYGGNAARTGGAARCARGTNYTNGTNATHCCNMGNATHAAYMGNGCNGCN ACNTCNGTNAARTGGTCNCCNAARGARAAYAARTTYGCNGTNGGNAGYGGNTCNMGNYTN ATHGCNATHTGYTAYTAYGAYGAYGARAAYAAYTGGTGGGTNAGYMGNCAYATHAARAAR CCNATHMGNTCNACNGTNACNTGYYTNGAYTGGCAYCCNAAYAAYGTNYTNYTNGCNGCN GGNTCNACNGAYTTYAARTGYMGNGTNTTYTCNGCNTAYCARAARGARGTNGAYGARMGN CCNGGNGCNTGYTCNTGGGGNACNAARATGCCNTTYGGNGCNYTNATGGCNGARTTYAGY AAYGGNGGNGGNGGNTGGGTNCAYTCNGTNTGYTTYTCNCCNAGYGGNACNYTNGTNGCN TGGGTNGGNCAYGAYTCNAGYGTNTCNGTNGCNGAYTCNTCNAAYGGNAAYGARYTNTGY ATGATHAARGARAGYTTYYTNCCNTTYATGAGYGTNACNTGGGTNACNGARAAYTCNYTN GTNGCNGCNGGNTAYGAYTGYAAYCCNATGGTNTTYTCNTAYAGYGGNGGNAARGTNACN TGYCARGGNAARYTNGAYGTNCCNCARCARAARGARACNGGNACNATGAGYGCNATGAAY MGNTTYAARAAYYTNGAYAARAARGCNACNGARAGYGAYAGYTCNCCNGARATGAARACN CARCAYCARAAYACNATHACNCARGTNTCNATHCAYACNGGNACNAARCARGAYGCNAGY AARATHGTNACNAGYGGNGTNGAYGGNAAYYTNATHYTNTGGGAYYTNAAR--------- ---------------------------------ATHGARAAYCARAARACNGARTGGAAY GCNACNTCNAARATHMGNTCNYTNGARAARGCNAARCAYAARCCNGGNGGNGGNGAYGTN AARATHGARNNNAARAARACNGARTGGAAYGTNACNTCNAARATHGGNTCNYTNGARAAR GCNAAYCAYAARCCNGGNGGNGGNGAYAARAARATHGARACNGTNAARACNGARTGGAAY GCNCARTCNAARATHMGNTCNYTNGAYAAYGTNAARCAYCARCCNGGNGGNGGNGAYAAR CARATHGARACNCAYCARYTNGAYTTYAARGCNAGYCCNMGNATHGGNTCNYTNACNCCN CARMGNYTNAAYTCNTCNGGNAGYGAY---ACNTGYAGYATGTGYCCNGTNCCNCARYTN ACNGCNTAYTGGACNAGYCCNCCNGCNTGYCCNMGNAARTTYTTYTGYGAR---AARTCN GCNTGYTTYTCNTCNGGNTGYYTNMGNGAYGGNAARAAYTTYACNATHTTYGTNGCNTTY GTNTTYTTYTCNTAYATGYTNATHATGGAYATHATHYTNTAYTGYTAYTTYCARAARGCN AAYYTNGTNCARGAYTCNAARGGNGGNTCNYTNGARGARATHTAYACNCCNTTYACNCAY YTNTCNGTNAARGCNATHYTNAAYGAYCARCCNAGYCARTAYYTNATHGCNCCNAGYTGY GARTGGYTNGARTAYTTYACNAAYTTYGCNGCNACNTTYTAYTTYATHACNCCNAAYGTN GTNTCNTTYACNCAYYTNATHGTNGGNTTYATHTCNGGNAARTTYGTNTCNTCNGARAAY YTNTCNGAYMGNMGNATHGGNGTNGTNYTNTTYGARATGMGNACNTGGYTNGAYGCNTTY GAYGGNACNYTNTTYMGNGCNMGNCCNGGNAAYCAYYTNAARTAYAAYTCNGTNCAYGAY ACNYTNGGNTAYTAYGTNGAYTCNGCNTTYGAYACNYTNGGNGGNGCNTTYYTNTGYTTY GGNATGTAYTTYTAYYTNYTNAARMGNTTYGGNCCNCCNMGNATHACN------YTNCCN TGYTGGYTNTCNTCNAGYCCNGAYAGYCARACNAARGCNCCNYTNGTNAAYGARACNGCN ---------AARGARAGYTAYAGYCCNYTNTAYYTNTTYTGGAARGCNYTNTCNTTYGGN ATHGTNYTNATHGTNTCNGGNATHACNTGGGAYAAYATHGTNGTNCARTTYTCNGARGTN TTYCARACNGARYTNAARGAYCCNGARYTNTCNGCNYTNCARYTNCARYTNTGYCAYTCN GGNACNACNATGTTYYTNTTYCARATGTGGMGNYTNATHGGNTCNCARTGYATGYTNAAY TAYATHYTNGTNATHATHTTYTTYGAYMGNATHTGGGARTTYYTNAARACNGCNCCNTGY GTNYTNYTNGTNATGATHATHAGYYTNTAYGTNGCNTGYACNYTNTAYGTNCAYCARATH MGNMGNCARYTNAAYATHCCNAARYTNATHGTNTTYGAYYTNGAYTAYACNYTNTGGCCN TTYTGGGTNGAYACNCAYGTNAARCCNCCNTTYAARAARGAYTCNAGYGGNAARGTNMGN GAYGCNMGNGGNGAYCAYGTNAARCAYTAYCCNGAYGTNCCNGARATHYTNTCNCARYTN CAYTCNGAYGGNTTYAARYTNGGNATHGCNTCNMGNACNAGYGCNATHGARGAYGCNCAR AGYYTNGTNAGYYTNTTYGARTGGGAYCARTTYTTYGAYTAYMGNCARATHTTYTCNGGN TGYAARATHACNCAYTTYAARAARYTNCARGCNGCNAGYGGNATHCCNTTYCARGAYATG YTNTTYTTYGAYGAYGARCAYMGNAAYATHGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TTYATGAAYGAYTCNGGNAGYAGYTCNATHAAYAGYTCNAARATHGARGCNGTNTCN AAYYTNYTNAARAGYCCNTCNTGYCAYATHGTNTCNCARTAYATGMGNGAYMGNGARGAR TAYMGNATHGARMGNCARGARMGNGCNGARGTNGARAARGARMGNMGNYTNAARGARCAR AARCARAGYTCNAGYGARGARGARATHAAYGARMGNTAYGCNGARYTNYTNGCNMGNAAR GARGGNGARMGNYTNAARMGNMGNGCNYTNAARAARMGNAARGGNAARGAYATHYTNTTY TCNATHCCNGARGAYMGNAGYCAYGAYCCNTCNCCNGCNCARTCNAAYACNCCNTCNMGN CARCCNAARTCNACNCAYGCNMGNCARGCNCAYYTNATHGAYCCNGAYATGTTYAARYTN MGNGARAARATHTCNAARCARAARAGYAARGTNGAYAARGAYATHYTNAARGARATGMGN MGNATHGARAARYTNAARACNYTNGARGGNYTNYTNYTNGARAARAARAARGGNAARATH TCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNGAYTCNTGGTCNGTNATHYTNAAYGGNGARGTNGARATHATGMGNCCNTCN GGNGTNMGNGARMGNYTNCARATGGGNGAYAGYTTYGGNATHAGYCCNACNATGGARAAR YTNCAYCAYCARGGNGTNATGCARACNATHGTNAAYGAYTGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGAARGTNTAY AARTGYYTNATHTCNGGNGAYGARYTNTTYTCNGARATHCAYCARCCNGARGAYAARGGN GGNTTYTAYGTNGTNAARGCNAARTTYATHACN---MGNAARGCNGAYGAYGTNGAYGAY AGYGCNATHGGNGGNAAYCCNAGYGCNGARGARGARCARGAR---GGNAAYGARAAYGGN TCNGTNAGYGGNATHAAYGTNGTNATGGAYCAYMGNYTNGTNGARACNGGNTTYGGNACN AARAARGARTAYACNACNTAYATGAARGAYTAYATGAARAARATHYTNCARYTNYTNAGY GARGAYAAR------------GTNGARAARTTYAARACNGARACNCARGCNTCNTTYAAR GARGCNTGYAAYAARTTYAARGAYYTNCARTTYTAYYTNGGNGARAGYCARAAYATGGAR GGNCAYATHGCNYTNGTNGARTGG------------------------ATHGAYGARGTN CCNTAYTTYTAYTTYTAYAARTAYGGNGTNMGNGARGARAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNCCNTGYCCNATHMGNGGNTAYGAYGGNTCNGARAGYTCNGAYYTNGAY GARMGNGAYCAYGAYGGNGCNGTNTCNGAYGARGAYACNGCNGAYGCNAGYGARACNGAR GARAARACN---CCNAARCCNCARAARCCNACNAGYAAY---GGNAAYCARMGNACNGAR ATHAARGARCARATGTAYCARGAYAARYTNGCNCARATHAARAARCAYATHGTNATGYTN CARGARGGNACNYTNCARGARTTYYTNAARMGNACNAARAARATHGARYTNAAYTAYMGN GARMGNYTNMGNCARAAYGARATHTGYAARAARGTNGAYATHGARAARGCNGARMGNAAY TAYCAYATHGAYTGYGARAAYGCNCARAARGARTTYGARGARAARGGNMGNGCNYTNAAR GARMGNYTNATHAGYCAYTTYCARGARAARAARATHGAYYTNAARGARACNYTNATHAGY GAYYTNAARGARAARMGNGGNATGATHGARYTNGARMGNCARACNGTNGAYYTNAAYGGN GCNGAYTTYATGGARGTNAARCCNACNGTNACNMGNAARYTNMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ACNATHTGYCARGAYTGGGARATHAGYCARCAYCARAARTCNGAYTCN ACNTTYACNGARAARYTNYTNYTNGCNMGNAARCARYTNYTNGGNYTNGTNCCNACNATH CAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TAYCAYGTNGTNGAYCCNGCNGTNGARGCNGCNCAR GCNMGNYTNGAYGCNATGMGNAARGGNAARTCNACNGGNAGYAARATGMGNAARYTNAAR TCNATHMGNAAYTTYTCNYTNGARTCNGTNTCNGCNTCNTCNAARACNAARATHGCNACN TCNGCNACNGCNGTNGCNCCNYTNCCNCCNCCNYTN------------------------ ---------------------------------ATHGARGARATGGARGTNTCNCAYGGN GTNATHATHMGNGARGGNGGNMGNGTNAARAARGGNCCNGGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGYTNMGNATHGGNGTNATHGGNGCNGGNATHATGGGNYTNTCNAGYGCNGTNAGYGTN CARCARGCNTTYCCNCAYGCNAARGTNACNATHATHGCNGAYCARTTYGGNGARGAYACN ACNAGYTCNGGNGCNGGNGGNTTYTTYMGNCCNCAYYTNGAYGAYATHYTNCAYGGNAAY GAYCCNGARGTNATGAARCARTGYATHMGNGAYTCNTGGAARCAYTAYAGYAGYYTNGCN ATGTCNCARGARGCNAARGARAGYGGNCARTTYYTNGTNTCNGGNATGATGGCNTAYTCN AARCCNAARGAYGAYAGYTAYGTNYTNATGAARGARTGYTGYTTYGAYTTYCAYCARATG ---CCNGTNAGYGARYTN---AARCARMGNGGNGTNCCNTAYGARTTYGCNTAYTCNTGY AARTCNGTNATHTCNCARCCNACNATHTAYATGGAYTGGYTNACNAARAARTTYATGTCN AAYGGNGGNGARYTNCARAGYMGNACNGTNAARAAYTTYGAYGARYTNTAYGGNAARTTY CARYTNGTNATHAAYTGYTGYGGNYTNMGNGCNCARAGYTTYYTNAAYGAYAARGARTGY TTYCCNGTNMGNGGNCARYTNGTNATGGTNAARGCNCCNTGGATHAARAAYTTYTAYTTY TCNGARGCNGAYATHTAYATHATHCCNCARGTNGAYMGNATHGTNGTNGGNGGNATHMGN GTNAARGGNGAYTGGAAYGAYGCNGTNGAYCCNGARACNAGYGAYAGYATHATGMGNAAR GCNGARACNGTNTTYCCNGARYTNAARGGNGCNCARMGNYTNTCNAGYTGGGCNGCNYTN MGNCCNGGNMGNACNAGYATHMGNYTNGARYTNGARTCNATGGAYYTNGGNGGNAAYMGN MGNYTNCCNGTNATHCAYAAYTAYGGNCAYGGNGGNCAYGGNATHACNYTNAGYTGGGGN ACNGCNGTNCARGCNGCNAARYTNGCNMGNAARGCNATHTCN------------------ TCNACNCCNGGNTCNCCNCCNYTNCCNAARAARGGNGTNTAYAAYTTYGAYTTYGAYAAY YTNGAYGARTTYTCNAAYCCNTTYGARTCNAARAAYAARATGCARATGGGNTCNTCNCCN CCNATHCAY------TCNAAYAGY------TCNTAYCARTCNGAYGARAAYGARGAYCCN TTYAARTCNAARAARGCNYTNGCNAGYTCNCCNCCNGGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR ACNGGNYTNTAYTGGGTNGAYATGGGNYTNGAYTGGMGNCCNMGNTAYCCNMGNTAYTCN ACNACNTTYTAYAARACNYTNGTNAARGAYMGNGGNYTNACNAAYMGNACNYTNAAYTAY MGNGTNTAYCCNGCNGAYMGNGAYGARTTYTAYTAYGGNAAYTTYCCNTCNGAYTTYATG TGGGGNGCNGCNACNTCNGCNTAYCARATHGARGGNGGNTGGAAYGCNGAYGGNAARGGN CCNAGYATHTGGGAYACNTTYGCNCAYGCNAAYMGNYTNGCNGGNTCNCARACNGGNGAY GTNGCNTGYGAYAGYTAYCAYYTNTAYCARGARGAYATHMGNATGYTNCARTCNYTNGGN GTNAAYTTYTAYMGNTTYTCNATHGCNTGGAGYMGNGTNATGGCNGAYGGNACNTCNMGN TCNATHAAYAARGCNGGNATHAAYTAYTAYAAYAARYTNATHGAYGGNYTNGTNGCNGCN AAYATHACNCCNATGGTNACNYTNTAYCAYTGGGAYYTNCCNCARGCNATHCARGAYCAR GGNGGNTGGAARAAYGAYTCNGTNYTNCARYTNTTYGARGAYTAYGCNMGNYTNTGYTTY GARCARTTYGGNAAYMGNGTNAARTAYTGGATHACNTTYAAYGARGCNTTYGTNGTNAGY TGGYTNGGNTAYGGNATHGGNGTNTTYGCNCCNGGNGARTAYGAYCCNGGNACNGGNGTN TAYMGNGTNGCNCAYAAYATHATHMGNTCNCAYGCNMGNGCNTTYCAYGTNTAYAARGAY CAYTTYAARGCNMGNTAYCARGGNAAYGTNGGNATHACNYTNGAYATHGARTGGAARGAR CCNYTNACNGAYTCNAGYGARGAYGCNMGNGCNGCNGARMGNGCNATHCARTTYAARYTN GGNTGGTTYGGNAAYCCNATHTAYGGNGGNACNGGNGAYTAYCCNCARGTNATGAARGAY TTYGTNGCNMGNAARAGYAAYGARCARGGNYTNGCNCARTCNMGNYTNCCNGCNTTYACN GARGARGARAARATGYTNAAYAARGGNGCNTAYGAYTTYYTNGGNATHAAYCAYTAYACN TCNAAYYTNGTNGCNGAYAAYCCNMGNACNMGNAGYGAYCARAAYTAYGARCARGAYCAR GAYATHGAYACNAARGCNGAYCCNTGYTGGCCNGGNACNGARGCNAGYTGGYTNAARGTN AAYCCNTGGGGNATHMGNAAYATHATHMGNTGGGCNMGNGAYCAYTTYAAYAAYCCNCCN ATHATHATHACNGARAGYGGNMGNCCNGAYATHGCNGARYTNGAYGAYCARGGNMGNATH TTYTAYTAYAARCAYTAYACNAAYGARATHYTNAARGCNATHMGNYTNGAYGGNGTNAAY GTNYTNGGNTAYACNGCNTGGTCNYTNATGGAYAAYYTNGARTGGACNAGYGGNTAYTAY AGYAARTTYGGNYTNTAYMGNGTNGAYTTYGAYCAYCCNAAYMGNACNMGNACNCCNMGN GCNTCNGCNGCNTTYTAYAARCARYTNGTNGCNCARAAYGGNTAYGTNAARTGGMGNTTY GCNAAYGTNATHATGGCNGCNTTYTTYTTYYTNGCNGGNTTYGCNAAYATGAAYGAYAGY GAYTGGTAYATHTGGACNCCNATGTAYTTYTTYCCNGCNYTNYTNTGYTCNTTYGCNTTY GTNCARCCNACNGCNACNNNNAAYGGNYTNTGGCARACNTGYATGTCNATHGARYTNGGN YTNACNATHACNATGACNYTNTAYCARATHTCNAARATHTTYGGNATGTAYACNMGNATG GCNTCNAAYCCNYTNATHCAYGARGARGGNMGNGARATGGGNGGNYTNATHATHATHYTN GCNTGGACNGGNYTNTTYYTNTTYCARAGYMGNTCNTCNTCNAARGCNCCNAGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARCCNTCNATHTGYGAYMGNTGYGGNGTNACNTTYAARACNMGNGGN GGNYTNMGNGCNCAYATHCAYMGNCAYGAYGARAAYCARACNCAYTGYTGYCAYATHTGY GGNAARGGNTTYAARYTNATGTGYGCNYTNAARMGNCAYYTNAARACNCAYACNAAYACN AARMGNAARGCNTGYCAYGTNTGYAAYAARATHTTYAAYGCNGCNAAYATHATHMGN--- CAYATGMGNGTNCAYACNGGNGARMGNCCNTGGAARTGYACNGAYTGYGGNAARGCNTTY ATHCARCAYGAYGARTTYAARMGNCAYATHMGNMGNCAYACNGGNGARMGNCCNTGGAAR TGYAAYCARTGYGAYAARTCNTTYATGCARAARTTYACNTAYACNAARCAYATGMGNYTN CAYACNGGNGARAARCCNTGGAARTGYAGYYTNTGYGAYCARTCNTTYGCNATHMGNTCN AAYTAYACNAARCAYTTYATGAGYCAYTGYGGNGAYCARCCNCAYGARTGYAGYYTNTGY GCNAARGTNTTYAARAGYAARGARAGYYTNMGNGCNCAYGTNAAYATHCAYATHGGN--- ---GTNTTYACNTGYCARATGTGYAAYAARACNTTYAGYTTYYTNGCNAAYYTNAARMGN CAYATGGARGTNCAYTCNAARGTNMGNTCNTTYAARTGYGARGTNTGYGGNMGNAGYTTY GCNCARAARGTNACNYTNGAYYTNCAYYTNTGGACNCAYAAYTTYAARMGNATHAARMGN CCNCARGCNGAYAGYAGYGARGAYGAYGAYTTYGGNAARGGNAGYGGNATHAARGTNGAY AARGARAARYTNAARAARYTNAGYGARYTNTTYCCNGGNGGNGAYATHAARMGNATGAAR GCNGCNYTNTTYGCNTAYCARAARGAYTTYCARAARGCNATHGARTTYATGAARTCNACN GGNTCNAARACNTCNCCNGCNTCNGARAAYTCNGAYGARGARYTNCCNGARATHACNGGN AGYMGNAARMGNATHMGNGTNAAYTCNGARACNCCNTCNCCNACNAAR------------ ------------------AARCCNGGNCARGAYTCNYTNACNTTYYTNAARGARTGYTTY CCNGGNAARTCNGARCARCAYATHCARAARATHYTNAAYGARAAYGAYGGNGAYACNGAR MGNGCNTCNGTNGCNYTNACNAGYGARGAYAGYCARGAYGCNAARGTNGCNGARTCNTTY AAYCAYAGYYTNCCNMGNAARGAR---TCNAARYTNGCNAARATHGTNAARGCNCARAAR ---AAYGGNAGYTCNAARMGNMGNGAYAAYGAYATGAGYGAYGAYGAYGARGARTAYGGN AAYGARATHGAYAGYGGNGAYAGYGAYGAYAGYGARGARTTYGARAAYMGNACNAGYGCN GARGTNACNAAYATHYTNCARTTYTTYGARGARGCNACNGTNGARGARATHAGYGCNATG CCNGGNTGYTCNAARAARAARTCNGARYTNATHATHAGYYTNMGNCCNTTYCARAAYTGG GAYACNYTNTGYTTYAARTTYAAYAAYGARAARTCNYTNTCNACNTCNYTNATHTCNGGN TGYAARGARATHATGMGNGTNMGNAAYATHATHCAYMGNYTNATGGTNMGNTGYGARAGY ATHTCNCARCARATGGARAARYTNGTNCAYACNYTNTCNGGNGARAGYAARGAYGARGAR YTNAAYGTNGAYGGNMGNYTNGTNAARCARCCNGAYYTNYTNGAYGCNACNYTNTCNYTN AARCCNTAYCARYTNATHGGNYTNAGYTGGYTNMGNATHATGCAYGARCARGARYTNAAY GGNATHYTNGCNGAYGARATGGGNYTNGGNAARACNGTNCARGCNATHTCNTTYYTNGCN CAYYTNYTNGARGARGGNGARGCNGGNCCNCAYGTNATHATHGTNCCNTCNTCNACNATH GARAAYTGGYTNMGNGARYTNCARMGNTGGTGYCCNGCNYTNAARGTNATHGTNTAYTAY GGNTCNCARGARGARMGNMGNGCNGTNMGNCAYTCNATHTTYGTNGAYGARGARGARTTY AAYGTNYTNYTNACNACNTAYAAYATGGCNACNGGNGGNGTNGARGAYMGNGTNYTNTTY AARAARTTYGAYTTYCAYTAYGCNATHTTYGAYGARGGNCAYATGYTNAARAAYATGTCN TCNYTNMGNTTYCARAAYYTNATGAARATHGCNGCNGARMGNMGNYTNYTNYTNACNGGN ACNCCNYTNCARAAYAAYYTNYTNGARYTNATGTCNYTNYTNTGYTTYGTNATGCCNGAR ATHTTYCARGGNAARACNGAYTCNYTNAARAARATGTTYGCNATGATHTCNMGNGCNGAR GAYAARCARAARAGYMGNTAYGARTGGGARAARATHGCNCARGCNAARMGNATHATGAAR CCNTTYYTNYTNMGNMGNYTNAARAARGAYGTNYTNAARCARYTNCCNAARAARMGNGAR CARATHTAYAARTGYAARYTNACNGARCCNCARMGNACNYTNTAYGAYGGNYTNATHTCN AAYTAYGCNCARCARATGGARAARGARAARGARGAYGGNGCNGGNGGNGGNATHGGNTAY TTYATGCARTTYMGNAARGCNGCNAAYCAYCCNYTNYTNYTNMGNAAYYTNTAYACNGAY GAYATHYTNAGYCARATGGCNAARAARATHGCNAARGARCCNTCNCAYMGNGAYMGNGGN GCNYTNCCNAARYTNATHCARGARGAYATGTCNYTNATGAAYGAYTTYGARYTNATHGGN YTNTGYMGNCARTAYAARAARCARGTNGGNAARTAYGARYTNGAYTCNTCNATHATHGCN AARTCNGGNAARTTYGARAARYTNGAYGARYTNYTNCCNGCNATGAARGARMGNGGNGAY MGNGTNYTNYTNTTYAGYCARTTYACNATGGTNYTNGAYATHGTNGARYTNTAYYTNGAR CARMGNCARCAYAARTTYATHMGNYTNGAYGGNCARACNCCNGTNACNGAYMGNYTNCAR YTNATHGAYMGNTAYAAYAAYGARCCNGAYATHTTYATHTTYYTNYTNTCNACNMGNGCN GGNGGNYTNGGNATHAAYYTNACNGCNGCNAAYGTNATHATHYTNCAYGAYATHGAYTTY AAYCCNTAYAAYGAYAARCARGCNGARGAYMGNTGYCAYMGNYTNGGNCARAARMGNGAR GTNCARGTNATHMGNYTNATHTGYGARGAYACNGTNGAYGARTCNATGYTNMGNTGYGCN AAYGARAARYTNGCNYTNGARAARGAYGTNACNGGNTCNGGNGCNGARGARAAYCARGAR AGYTCNAARGAYGTNGCNAAYYTNYTNAARGARGTNYTNAARCARCAYCARAARMGNTCN CARGAYTAYAGYATGGGNATHYTNGGNGTNACNMGNCCNAARGAYTGYAGYTGYCARGAR YTNYTNTCNYTNCCNAAYATHGTNCARTAYGGNTGGYTNMGNAARMGNAGYYTNMGNAAY AARGTN------YTNGCNYTNAAYTGGCCNMGNYTNTAYGTNATHYTNGCNAGYAARTGY YTNTAYCAYTAYTCNAAYGARACNGCNAARAARCCNTCNGGNTCNGTNTCNYTNTAYGGN TTYAAYMGNATHTGYMGNGCNAGYGGNCARCARGCNAARGAYGTNGTNTGGGCNTTYAAR YTNGARCAYATHCARCCNTCNATHMGNTCNYTNTAYTTYTCNGCNTCNTCNGARAARGAR ATGYTNATHTGGATGMGNGCNATHAARCARGARATGATGATHGCNAAYGGNAARGAYCAR GARMGNAAYTCNGCNAGYGAYTCNCARGGNGARTCNATHGCNTCNGARGAYTCNTGGGGN YTNGCNGAYTAYAAYGCNYTNGARGGNGGNATHTAYGARGARGCNATGTGYAGYMGNCCN YTNTCNACNATGACNTCNAGYYTNGAYGGNAAYGAYAGY------------GAYTTYGAR GARGGNGARGARCCNGCN---------TCNAARGARTCNTTYCCNTCNTCNMGNGTNGAY AARCAYAARCCNTCNGARGCNAAYMGNYTNAAYCCN---------------TCNYTNATH AARCAYGGNGARGAYTAYTGGAAYTCNGTNAAYTTYAAYGGNTCNAARAAYGARGCNTCN GAYATHATHTCNTCNATHGCNGARGAYGGNGTNTTYYTNGTNMGNAARAGYATHGAYAAY TCNAAYGTNYTNGTNGTNTAYGCNGGNTCNACNMGNAARTAYAARATH---ATHGARATG GAYGGNGTNGTNACNYTNTCNACNACNGARCCNAARTTYGAYTCNYTNGARTCNYTNYTN TAYCAYTAYTTYGAYAAYGAYYTNCCNAAYACNAGYACNAARYTNCARTGYCCNTTYCAR YTNCAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARTCNAGYYTNGCNMGNGAYGGNACNATGCARGTNACNGCNAARGARGGNATHGAYTAY YTNAARTCNGCNCAYAARGAYACNYTNYTNAARGCNCARGGNGTNAARGAYGCN------ ------------------------------------------------------------ ------------------------------------------------AARCCNGCNGTN CARMGNGAYGGNACNATGGTNTCNACNGCNAARGARGCNGARMGNYTNYTNGAYGGNAAY AARCCNGAYGCNGAYGCNCARACNMGNGGNCARCARAARCARATHGAYGAYATHAARAAY GAYAARTCNGARCCNAARGCNAARAARGCNMGNYTNTCNAARGAYACNACNATGGCNGCN ACNGCNAARGARGCNAARGGNYTNYTNGCNGGNGARAARYTNGGNGAYACNMGNCARGAR ACN---------AARAGYAARCCNAARACNCCNYTNMGNAARAAYACNACNATGGCNMGN ACNGTNGARGARGCNAARTCNGTNYTNGAYGGNAAYYTNGAYACNAGYGARGGNMGNAAR ACNMGNTCNCARAGYMGNGGNGAYCCNCCNAARCCNTCNGTNAARAARYTNGGNACNATG CARCARACNGCNAARGAYGGNAARGCNTAYYTNAAYMGNGGNAAR---GGNAARAARGCN GCNAARGCNGCNGARGARGAYAAYGARGAY------------------------------ ------------------------------------------------------------ ---------------------------------------------CAYCCNACNCCNGAR MGNGARTCNTCNAARMGNGCNYTNGCNCAYTTYATHGARGARGCNGCNMGNATGAARGCN TCNAGYMGNYTNGCNTTYGAYTCNGGNACNTTYACNMGNCCNAARMGNCCNGCNAAYYTN AARGCNCCNTTYYTNGGNGARGGNGAYCARGTNCARAAYGTNCCNAAYGTNGCNGAYATH GARAAYYTNGCNAARCARCARGARGARAGYYTNMGNCARAGYGTNACNCCNGCNAARAAY ACNYTNMGNAAYAARCAYCCNYTNGTNGARGTNGAYGGN---GCNMGNACNAGYCCNAGY MGNTTYGAYGTNGARGGNTCNTAYATGAGYCARCAYMGNGGNAGYTTYAGYTCNGAYCCN AGYACNCCNCCNGAYAGYCCNCAYAAYAGYCARCAYTTYCARYTNAGYGCNTCNACNGAY GGNMGNGTNMGNMGNAAYYTNCCN---ACNTCNGGNYTNCARTAYMGNTCNCAYAAYTCN AGYGAYTCNAGYYTNGARMGNCAYAGYGTNGAYACNAAYGGNAGYGAYGARATHAAYYTN GCNCCNGARGCNATGMGNGCNCCNACNTCNMGNYTNCARCCNCCNMGNAAYTCNAAYTCN TCNTCNCCNAARMGNGGNATH---GGNYTNGCNCCNGGNYTNGCNAAR---CARCARMGN GGNGTNTCNCCNCARMGNCARAGYGGNYTNCCNACNGCNMGNMGNCARATHGCNMGNCCN TCNTCNGCNCCNMGNTCNTCNYTNCCNCARTTYMGNMGNCCNGTNACNCCNTCNTCNMGN CCNCCNACNCARTCNCARGARGCNAAYTGGMGNGAYGGNTGYTTYATGCCNAAYYTNCCN ATHGTNAARCAYACNGTNACNATGTCNGCNGTNGGNGGNGCNGTNYTNAARACNYTNACN AAR------------CARATGATGAARCCNCAYGTNCCNYTNATHAARTTYCCNAARMGN MGNCCNGTNACNCARTTYCAR---------MGNCCNYTNGGNAAYCCNAAYTCNGTNGAR TCNYTNGTNACNGARAAYATGGCNCCNAAYACNAGYAGYACNAGYTCNACNAARGTNAAY GCNAARGGNCCNTTYATHGAYTCNTCNGARYTNCCNACNMGNTTYMGNMGNAARCCNATH TCNTTYGARGARATHGARTAYATHGARAARGGNGGNCCNGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GCNAAYTCNGARGTNGTNACNGAYGAYGAR GAYGGNYTNCARCAYTTYGGNCARGGNCARACNGARCAYAARAARMGNMGNGGNYTNMGN MGNYTNTTYGGNAARYTNAARMGNAGYAGYTCNCARGAYYTNGARGGNGCNMGNGAYMGN CAYGGNGARCCNGGNGAYTTYMGNMGNGGNGGNGTNMGNGCNACNGCNACNGCNMGNYTN GCNTGGAAYMGNGAYGTNAARGGNMGNATHTCNAAYTCNGAYATHCCNTTYGCNMGNTGG GAYACNGAYMGNATHACNGCNTGGYTNAAYGAYATHGGNYTNAAYATGTAYYTNGTNGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TGYAARATHCAYACNCARGCNTCNCCNYTNYTNTTY CAYGTNTCNGAYAARYTNTGYGCNGARCCNATGAARMGNAARAARAARYTNGAYCCNGCN ATHGCNGCNGCNAARACNCARAARAARYTNAARMGNATHGAYAARGARATHAARMGNYTN TCNMGNATHGGNAARATHYTNAARCCNGTNGARGARATHGARGTNGAYMGNMGNAARYTN ATGGGNTCNGGNGARMGNAARMGNGARCCNACNGTNYTNACNTTYGARGARTCNGARTCN MGNGCNYTNYTNCAYAARAAYTGGACNGGNTAYMGNACNAAYMGNCAYTAYGARATGGTN TCNGARTTYTCNAARGTNGCNGCNGCNCARCARGARGCNYTNGARGARYTNMGNGCNGAR TCNGARGARYTNTAYCARGCNGCNATHAARATHGAYGARGTNTCNYTNCCNYTNACNTTY GARGGNCCNAARGARACNCCNCCNATHCARGGNTAYAAYCCNCCNGAYGGNGARTAYATH GAYACNACNMGNAARTTYATGGCNGTNAGYGGNGAYATGGARTGGAAYATHGAYATGGAR GTNAAYYTNTTYCAYGCNATGMGNGGNMGNAARCCNGTNGGNGTNAAYMGNCAYTTYCAR ATGATHGCNATHCAYGAYAARYTNTGYTCNYTNGCNAARAARGTNACNTCNAAYGAYGTN TGGMGNCAYYTNTCNACNYTNTAYGAYYTNCARGCNYTNAAYGARTCNGARATHGTNCCN TTYCCNAAYAARAAYGGNGAYTTYTCNYTNGGNGAYAARGARYTNYTNGARYTNTGYACN AARTCNTTYCCNMGNTCNGGNTAYATHGAYACNGTNCARAAYGARCCNATHAARAGYGAR GGNGGNGGNAARAGYATHTCNAARYTNAGYAGYAARCARGAYACNAARGTNGGNTCNCAR ACNCCNAARTCNGARTCNAARAGYGARCAYAAR---GCNAGYAGYACNTCNAARACNGAY AGYAARTCNGGNTCNAGYAGYMGNTCNTCNGAYTCNAARTCNTCNCAY------------ ------------CAYAGYAGYAGYAARTCNTCNCAYCARTCNAGYCARTCNAAYYTNCCN TCNCCNTCNCCNAARMGNACNAARMGNACNMGNAAYGTNAAYTCNGCNTCNGCNAGYCCN GCNACNCCNACNGARCCNCARTCNAARMGNMGNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ACNYTNAARTCNAGYTTYATGGAYYTNTCNYTNATGYTNYTNTTYYTNTGYGTN GGNACNYTNGTNTTYTCNAGYYTNGTNTAYTTYGCNGARAAYACNACNCARGCNTCNTTY TCNAGYATHCCNAARTGYTTYTGGTGGGCNGTNATHACNATGACNACNGTNGGNTAYGGN GAYATGTAYCCNGTNACNAAYYTNGGNTAYYTNGTNGGNACNGTNACNGCNGTNTCNGGN YTNYTNATGGTNGGNTTYACNGTNCCNGCNYTNGTNAAYAAYTTYGTNYTNTAYTAYAAY CAYGCNGGNTCNCAYATHGARMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNACNAAYYTNATHCARTTYTTYAARTCNACNYTNMGNAARTCNGCN AARGAYAARAARATHYTNYTNGGNGTNGARAARGARYTNATHACNTTYATHGCNAAYCAR TCNGCNCCNTCNTTYAARATGAAYGARATGAAYCCNTAYGAYMGNATGGTNGCNCAYMGN GTNGCNGCNTAYTAYGGNYTNGAYCAYAAYGTNGAYCARTCNGGNAARTGYATHATHGTN ACNMGNTCNCCNAARACNMGNATHCCNGAYCARMGNYTNGCNGAY------YTNGGNATH TCNCARGAYGGNCARTAYGARCCNAARATHGTNYTNAARAARMGNCARAGYTAYGAYGAR AAYCAYGGNMGNGGNCCNMGNAARGAYATGTTYGGN---ACNAARGCNAARTCNTTYGAR GARMGNCARCARAAYTAYGAYGARGTNMGNGARMGNATHTTY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGNCARMGNTGGGCNYTNGARCARMGNYTNGCNAARMGNAARCARGCN GTNGARTAYCARGARATHGARAARAAYGARAARGCNAARGARCARGAYGARMGNGTNAAR ATHTTYMGNACNYTNYTNGARCAYCAYGCNAAYGAYGGNTCNTTYYTNGARAARCARMGN GAYACNGTNGTNYTNGAYTAYGTNGAYGAYYTNGARAARYTNAARAARTAYCAYGCNGGN GARTTYAARCARTTYCARYTNGARAARTTYGARYTNYTNCARCARGAYMGNYTNGAYAAY TTYTAYAARYTNAAYMGNMGNCAYGAYAARGARAARGCNGCNYTNYTNCAYTCNGCNGAY AARTCNACNAAYCCNTCNGARTTYATHAARYTNTAYCAYGAYYTNATG------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGAYATHTTYTAYATHTCNGTNTGYTTYGTNGCNTTY---YTNATHTGYCCNGCNTTY GGNGARGAYCCNYTNGTNGTNGARTTYCARAAYGCNACNAARATHGAYGTNATGGAYGGN GCNCARATGGTNCAYTTYCARTGYCAYYTNAAYMGNGGNCCNATHTTYGTNATHAAYACN AARGTNCARATGGTN------------CAYTAYAAYCCNGTNACNGARAARGARAGYTTY ATHACNTCNTCNGGNAAYYTN------GARGARGGNATGCCNGARTTYTAYAAYGTNAAR GCNGAYCCNGAYACNCCNGAYGGNATGATHGTNGAYTTY------ACNATHAARACNGTN MGNCAYCARGAYGAYGGNATHTAYTAYTGYMGNGTNGTNTCNGAYGGNCARCARCARGCN GAR------------------MGNGARATHGTNGTNCAYMGNCCNYTNGAYGCNYTNCAY YTNYTNTTYAAYGAYYTNGCNCCNATHGCNGARACNCCNAGYGAYGCNGTN--------- ---CARATHGAYCCNGGNATGTAYACNGTNGCNTGYGTNGCNAARGGNAGYAAYCCNGCN ACNAARAAYGTNMGNYTNGCNYTNGARAAYGGNGAYATGATHACNGTNAARGAYCCNGTN TCNAARYTNATGAGYCARACNGARMGNATHTAYGARACNACNGTNAAYGGNACNGTNAAY ATHATGGTNYTNAARGAYGARCCNGTNCARCARATHGTNTGYCARGCNACNGAYTCNTCN GGNTCNTCNAARATHGTNATGYTNTCNYTNAGYGTNAAYAARTAYGAYCCNAARGTNCAY TGYAAYAARTCNGARGCNTAYAARGGNCARACNGAYTGYGTNYTNACNTGYACNGTNGAY CAYACNGGNATHGAYGTNGARAGYTAYMGNTTYCARATH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNAGYATHACNATHGAYTCNGARYTNATHAARAAYGARGGNTTYACNTTY--- ---GGNTCNAARAARYTNYTNACNYTNGCNCARGGNYTNTCNCCNTGYTAYYTNMGNYTN GGNGGNACNTAYGCNGAYTTYYTNAAYTTYAGY------TCNAAYGARGARGARGGNATH TCNTCN------------GAYAGYCAYGAYCAYCCNAARGARCCNAARGGNYTNAAYGCN ACNTCNGGNTAYYTNGAYCAYYTNGAYAAYAARAAYTAYACNATGACNGGNAARCARTGG GAYMGNATHATHAAYTTYACNAGYYTNGCNGGNTGGGAYGTNATGTTYGAYTTYAAYYTN TTYMGN------AAYGGNYTNTGGGAYCCNACNAAYGCNGARAARYTNYTNAARTAYTCN GCNGTNMGNGAYTAYAARYTNCARGCNTTYCARYTNGGNAAYGARCCNAAYTCNTTYAAR TAYAAYTTYAAYATHAGYATHCCNGCNGCNACNYTNGTNAARGAYTTYCARATHYTNAAR GCNYTNYTNACNMGNTAYCCNYTNTAYGCNAAYAARAGYYTNTAYGGNCCNGAYGTNACN AAYYTNAAYMGNCAYGCNTCNTCNMGNGGNTAYYTNCARGAYTTYGTNAGYGCNGGNGGN AAYCARACNGTNAARGARATHTCNYTNCAYCARTAYTAYYTNAAYGGNMGNATHGCNAAR GCNTAYGAYTTYTAYAGYGTNGCNGTNYTNGAYTCNYTNAARGARGARATHAGYATGGGN CAYAGYYTNGCNGGNGGNAGYTCNATHMGNYTNACNGARACNTCNTCNTGYTAYGGNGGN GGNGCNCCNGGNYTNTCNGAYMGNTTYGTNGCNGGNTTYYTNTGGYTNGAYAARYTNGGN YTNTCNGCNAARYTNGGNGTNACNAARGTNTTYMGNCARACNTTYTTYGGNGGNAAYTAY GCNYTNGTNTCNMGNGAYYTNCAYCCNAGYCCNGAYTAYTTYYTNTCNYTNYTNTAYAAR MGNYTNATHGARGGNCCNGTNTTYAAYGCNTCNACNGARCCNAGYACNAARCAYYTNMGN ATHTAYGCNCAYTGY---ACNMGNTAYTAYGGNCARTAYAARAGYGGNGCNYTNACNYTN TCNTTYYTNAAYATHCARAAYACNTCNATHCCNGTNAGYTTYGGNCARTTYYTNGAYCAR TAYTAYCAYGTNTAYATHYTNACNCCNGGNGAYTCNGCNGGNYTNGARTCNMGNTTYGTN AARYTNAAYGGNAARATHYTNCARATGYTNGGNTCNTCNYTNCCNCCNYTNGARCCNAAR CCNCAYMGNGGNGTNATHACNYTNCCNGCNYTNTCNTTYGGNTTYATHGTNGTNCCNGGN GCNCARGTNTCNYTNTGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATHTCNGAYCCNYTNGAYGAYCCNMGNTGGTCNGCNATGMGNGGNYTNYTNGAYTCN GAYGGNACNGARGARGTNGTNYTNGAYGAYAARCCNTTYGARYTNMGNATGGGNACNGCN MGNAARYTNMGNATGTAYAAYCARATGTTYGARGTNGCNGTNGAYTCNAAYGARMGNGGN ATHMGNATHGAYGGNCARYTNGTNTAYAARYTNGGNGARCCNATHAARGARGTNAARATH GGNGAYMGNYTNATHAARYTNTTYTAYCAYGGNYTNCCNAARCCNATHTGGYTNGAYGGN CARTAYCAYGARATGMGNATHGAYGCNCCNCCNMGNAAYGTNTTYGTNAAYGGNTGGCAR MGNGGNTTYCARATHGAYGGNMGNGAYATGATGYTNYTNGTNGAYMGNATGGARAARGGN CCNTGYGGNGGNYTNYTNMGNAARATHCARATHGCNGGNATHGARCAYGARATHAGYTTY CARTCNCCNCCNMGNCARATHYTNATHGAYGGNAARCCNTGYGARYTNAARYTNGAYAGY AARATHCCNTAYGTNATHATHGARGGNAAYCCNCAYGGNATHMGNTTYGAYGGNGARCCN AARACNGTNTTYATHGAYAAYCARCCNTTYACNATHCCNYTNGAYMGNGCNGARAARATH MGNYTNGGNGCNMGNCCNATGTAYTTYGCNTTYGGNGGNCCNGCNCAYGARATHATHATH GAYGGNAARTGGTTYGARGTNAARTTYGAYAAYGCNCCNAARAAYATHCAYYTNGGNAAY MGNAGYTTYTCNATHMGNATHCCNGGNCCNCARCCNMGNGTNAARATHYTNAAYCARYTN CCNCARAAYTTYGAYGTNTCNMGNYTNATGGTNATHAAYAARGCNGARGTNYTNMGNGCN YTNCCNACNCCNGCNGTNCARCCNAAYGTNCAYCARCCNATHMGNCCNACNCARATG--- CCNAAYAAYAAYCCNATGAAYCCNMGNCARATGAAYATHCCNACNGGNGARATGCARMGN CCNYTNCCNGGNTCNATGGCNMGNGCNGTNGGNTCNAAYTCNATHCARATHCCNCCN--- ------------CARCARAAYYTNCCNCAYAAYATHATHCARAARYTNYTNGCNGCNCAY TCNCARATGGTNTCNCARCCNCARMGNTTYATGMGNCCNGGN------------ATGACN MGNCARCARGTNCCNAAYAAYCCNGCNATHMGNCARATHGGNYTNMGNGGNCCNYTNGCN AAYGTNMGNCARTCNAAYYTNGGNYTNATGAAYCARCARCCNATHAAYAAYATGATHGCN CARAAR------------------YTNYTNAAYGAYGCNGCNAAYAGYATGATHMGNCCN GTNGTNCCNGGNAAYATG------------------------------AAYATHGARGAY CARATHTCNGGNGCNGCNAAYGARCARTCNGCNGCNATGGCNACNGGNATG--------- ------------------------------------------------------------ ---------YTNGGNGTNGTNATGAARCARTTYCARACNAARCCNCARAGYAAYGTNCCN TCNGGNGGNTCNGCNGGNGCNCCNCARYTNCCNGTNAARGTNTCNGARATGYTNAGYTCN YTNCARATGCARGGN------------------------------AARCCNGCNACNGTN ACNGARMGNCARATGGCNACNCCNTCNGTNCCN--------------------------- ---------------TCNCCNTCNACNGGNGTNTCNGGNACNGGNGGNGCNGGNGAYAAY GCNTCNAAYAAYCCNAGYTCNACNYTNGAYATHAAYAGYYTNYTNAGYAAYYTNGTNAAR GTNGGNYTNATHAARGAYGCNAARCCNACNGAYACNGCNTCNTCNCARTCNTCNTCNGAY AARAARAARGCNATHCCNGTNCCNGTNCARATHAARAAR---------------GARGAR CCNCARGTNGTNAAY------------ATHCCNGAYYTNACNGAYTTYGAYCCNAARAAR YTNAARATHCAYMGNGTNGARGTNATHGGNACNYTNCAYMGNGGNATHCARTGYCAYACN TGYTCNGCNMGNTTYACNACNGARGARCARGARAARTAYMGNGCNCAYYTNGAYTGGCAY TTYMGNCARAAYAARYTNGARCARGARGTNGAYAARGTNGCNAARAAYMGNAARTGGTTY TAYACNYTNGCNGAYTGGATHCARTAYGARGARYTNGARGAYYTNGARGARAARTCNMGN AGYGARATHTTYGARCARATGMGNTCNGGNGCNGARAARCCNGTNACNGGNGCNTTYGGN ATGGAYCCNCAYMGNGTNCARGCNYTNGARGGNAARGARTAYGTNAARAAYCCNGTNGCN TCNGGNGTNGARGGNGARGAYGTNTGYGCNACNTGYGGNGAYCCNTTYGAYCARATGTGG AAYGARGARACNGARGARTGGATHYTNAARAAYACNATHAARGTNGAYGGNAARACNTAY CAYCCNATHTGYTAYGARGAYATGCARGARACNCCNACNCCNATHTCNGAYGTNAARACN AAYCCNYTNGAYACNGARATHTCNAAYYTNCARGARGARTCNTCNGARTCNYTNCCNGTN ACNNNNAARATHTCNAARCARAARAARATHGAYAAYCAYTAYAARGAYTCNACNTCNCAY TCNGARGCNCAYACNGTNGAYACNAARGTNGAYATHAARATGGARGTNGAYGAYCCNGGN CARTCNTCNTCNYTNGAYAAYCCNCCNAARAARGARCCNATHGCNTCNACNCARTCNCCN AGYYTNYTNAAYGTNGCNCCNCCNGAYAAYYTNAAYGAYGCNGARGGNAARTTYATHGAY GGNACNCARGGNCCNACNTTYYTNTCNGCNYTNGAYAARACNAGYGTNATHMGNAARGTN ATHTCNGTNAGYCARGARGAYCCNAAYTCNCCNTGGGARYTNGAYTCNAAYCCNACNCCN GARYTNTCNMGNACNCCNAGYCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARGARGARGAYGAYGAY GAYGTNGAYGARTTYACNGARGARGARATHGCNAAYGAYCCNTCNAARMGNATHYTNTGG GCNTCNGARAAYAAYAARATHGAYGTNGTNGARGARYTNYTNAARGARGAYTCNGGNYTN GTNAAYGTNTGYGAYAGYGAYGGNTAYACNCCNYTNCAYMGNTGYTCNTAYAAYAAYCAY CCNGAYATHGCNAARATHYTNATHTCNCAYCARGCNAAYGTNTTYGCNAARACNGTNGAY GGNTGGCAYCCNYTNCAYAGYGCNGCNMGNTGGAAYTCNGTNGARGTNGCNAAYATHYTN ATHAGYAGYGGNGCNGAYATHAAYGCNCARACNAAYGGNGGNYTNTCNCCNYTNCAYATG GCNGCNTCNGARMGNGARAAYGGNYTNATGYTNGARYTNYTNYTNAAYAAYCCNTTYATH GAYACNAGYYTNGTNTCNMGNGTNGGNGARACNGCNMGNCARATHTGYGARMGNATGAGY TCNCAYCAYACNYTNTTYGARYTNMGNGARGARTGYGTNAAYCARYTNAARAGYGGNCCN GTNAARACNATHAARGARTAYGAYCARCARGTNAGYGAYYTNACNAARGARAAYTTYAAY YTNAARYTNMGNATHTAYCAYATGGARCARMGNATGGARCARCARTAYGGNGAYGARCAR AAYGTNTTYAARACNAAYATHGARYTNAARGTNYTNGTNGAYCAYYTNMGNGARGARYTN AAYGARAARCARGTNTAYYTNCARAARGCNGCNCARGCNGTNAGYACNATGACNGTNAAY CAYCARCARGCNGARGARGCNATHMGNCARCARTGYGTNCARCARGGNGARAARGAYYTN GTNGAYYTNAARCARGCNYTNGARMGNGCNACNCARGARTGYGARAAYAGYMGNMGNCAR GCNGARGARGCNACNMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNAAYAARYTNAARAARYTNYTNGGNGAYGTNTAYGCN CARCCNGGNGARGARGGNTGGMGNYTNTGYCAYTAYTAYTAYAAYAGYYTNGGNATHAGY YTNGAYGGNATHGTNCARCARGCNGTNGAYMGNACNMGNCARACNCARGTNGCNCARTAY GGNMGNGGNYTNYTNGAYTTYYTNGAYAARAARYTNTTYTCNYTNTTYTCNYTNGAYTCN YTNYTNGTNYTNYTNCARAGYCARGAYCARTCNGAYATHCAYCAYAAYTCNCAYGTNAAR CARGTNYTNGARYTNGTNYTNAAYGAYGAYMGNMGNAAYTAYATHTTYGAYGARGCNGTN AAYYTNYTNTGYGARATHTAYATHTCNYTNYTNAARGARAARAARGCNTCNAGYACNCAR ATHAAYCARMGNCARCARATGAARTTYTCNYTNCCNAGYGGNAAYGGNTTYTTYAGYCCN MGNTTYGGNTGGYTNGAYCARYTNCCNCCNTTYTAYAGYCCNGAYCARATGYTNMGNCCN TGYCARMGNYTNGARGTNAARMGNGTNCCNGGNAARGGNTCNMGNATGGGNTCNAARCCN GTNTCNYTNACNCCNTCNAGYCARGARGAYAARGCNTGYTCNTGYTGYYTNTGYCAYGAR AAYYTNYTNAARYTNCARTCNYTNYTNTGYTCNCCNAAYYTNACNCCNAGYYTNGCNCAY CAYATHYTNGAYYTNYTNTGGGAYAGYATHCARYTNYTNTGYTTYACNAARATHGAYTGG AARGTNGCNACNGARAAYATHGTNCARMGNTAYCCNAGYGTNGTNGCNAAYTTYTCNTCN YTNTCNTAYGCNGGNGAYATHTCNAARTAYTCNTTYYTNATGAGYTCNATGGARAAYATG YTNAARTGYTCNACNTCNACNCCNACNAARGAYGARGARGCNTGYGTNAARGCNTAYAAR GAYYTNYTNAAYMGNYTNGCNGARACNTTYCCNCCNGCNCARTTYATHCARYTNYTNCCN AARGAYAGYAAYYTNTTYTTYYTNYTNCCNTTYATHACNMGNAAYYTNGARYTNGARAGY TCNAAYTCNYTNAARMGNAAYATHYTNYTNATGGGNAARGARYTNYTNTAYCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNAAYAARCCNAARCARACNYTNAARTTYGAR GGNTGYTTYCARTCNTGYTCNGARGAYGGNGTNGTNCARYTNYTNCAYGGNAARYTNGCN GTNGGNTGYGGNGARGGNMGNGAYTTYATGGTNAGYGTNCARGCNTCNGCNYTNACNGTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ACNCAR GTNAARACNYTNYTNGARTCNTCNATGGCNACNGTNYTNAAYAAYYTNGAYATGTTYGAY YTNGARGARTTYCARGAYGARTAYATHATHAAYYTNATGATHCAYMGNYTNAARMGNGAR AARGCNGTNACNAAYAARGCNYTNTCNTGYYTNTTYGTNCCNGCNYTNAGYMGNGTNAAY YTNCAYGGNGTNTTYYTNACNAAYAAYACNYTNMGNYTNYTNTGGACNCARTGYCCNAAY YTNTGYAGYYTNAAYYTNAGYAAYAGYGGNTAYATHGTNACNGAYACNGTNYTNGTNCAR ATHGCNAARAAYYTNCCNCAYYTNGARGARYTNAAYYTNACNMGNTGYTCNCAYYTNACN GGNAARTGYYTNTCNATHYTNACNAARMGNYTNCCNTCNYTNAARMGNYTNTAYGTNGCN GGNGTNCCNTCNATHACNCCNGCNAGYGCNMGNCCNTTYYTNAGYGARTGYAARGARYTN ACNYTNYTNGAYGTNTTYTTYATGAARACNACNMGNGARGARTTYGARACNYTNACNTCN YTNGCNGARAGYMGNGGNATHMGNYTNYTNYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATHCCNTAYYTNGGNAGY AARATHAGYYTNYTNTCNAARGCNGARATHMGNTAYGARGGNACNYTNTAYACNATHGAY CCNAAYGARGCNACNGTNGCNYTNGCNAARGTNMGNTCNTTYGGNACNGARGAYMGNCCN ACNGAYMGNCCNYTNCCNGCNMGNAAYGARGTNTTYGARTTYATHATHTTYMGNGGNCAY GAYATHAARGAYYTNCAYGTNTGYGGNCCNCCNAARCAYAGYCAYGAYACN---GGNGTN CCNCCNGAYCCNGCNATHGTNAARTCNTCNCARCCNCCNCCNGGNCCNGCNGGNGCNGCN TTY---------CCNGGNGCNYTNGGNTAYGCNGGNGGNCARGGNTAYCARCCNTTYACN CARCCNYTN---TTYGTNAAYCARGGNCARCCNGCNCCNGGNTTYGCNCCNCAYCCNGGN CAR--------------------------------------------------------- ------------------------------------------GCNGGNTCNCARAGYTCN ACNCCNCCNYTNAGYMGNAARTCNCCNACNTCNGAYCARGGNATHCARGTNCARTCNMGN ACNCCNGAYAARTCNGGNTAYGARGGNCAYCAYCARAARCARCCNCARCAYCARCAYCAR CARCAYCAYCAYCAYCCNMGNGAYTTYCCNMGNGGNCAYGGNMGNCAYGGNGGNGGNGGN GGNGGNGGNCARCAYMGNATGGAYCARMGNGAYMGNGGNMGNGGNGAYGAYCCNMGNGGN GAYMGNAAYGTNACN---TCNTTYGTNMGNGGNMGNGGNGGNGGNMGNGGNCARCCNATG MGNGARGGNAGYGGNGCNATGMGNGGNTCNCARGGNGGN---------------MGNGGN GGNMGNTCNTCNGARCCNYTNAARTTYGAYACNGAYTTYGAYTTYGARACNTCNAAYGCN CARTTYGAYAARGARGAYATHGARAARGARYTNAARAAYYTNACNYTNACNGAYAARCCN GTNAAYGGNGARAARGCNGARGARGAYCCNGARATHGARGARGARGARGARGARGARGAY GAYGAYCARGTNATHTAYTAYGAYAARAARAARTCNTTYTTYGAYAAYATHAGYTGYGAR TCNACNGARAARGCNMGNGGNCARMGNGTNACNTGGMGNGARGARMGNAARYTNAAYAGY GARACNTTYGGNATHTCNGARAAYTAYMGNMGNAAYTAYMGNGGNMGNGGNGGNTGGMGN GGNGGNAAYCARMGN---GGNTGGMGNGGNMGNGGNMGNGGNGGNGGNTAYAAYMGNGAY GGNGGNTAYTAY---GGNAAYMGNGGNGGNMGNGGNMGNMGNCCNGARTGGGAYTAYAAY GAYMGNMGNMGNATGGARGGNCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNYTN GARATHAGYAARTAYTCNGCNAAYYTNGARATHYTNTCNGTNYTNTAYAAYAARAAYATH ACNAAYCARGGNGTNTTYGCNGTNTTYATGGCNYTNGAYACNACNYTNMGNAARYTNAAR TCNTTYAGYTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GTNCCN TAYGTNGARGARTTYMGNGARTTYTTYYTNACNAARCAYGAYYTNAAYGCNTCNAARACN YTNGAYTGYCARAARYTNCARGCNGTNGTNATHTTYMGNMGNGAYTAYGTNGCNCAYCCN MGNAAYAARAARGGNMGNGTNGTNMGNAARTTYTCNAAYGARGAYGARATHYTNCARTCN GTNMGNGAYACNYTNGGNCCNTCNGCNACNGTNMGNGGNGTNCARYTNGAYACNATGACN ATGMGNAARCARYTNGCNATHATHTCNTCNTGYGAYTAYCCNGCNGARGTNGARGTNTCN TTYGARGARTTYAARTTYGTNGARCARGTNYTNCCNTGYTCNGTNGTNCCNGARYTNCCN GARCAYTCNTCNTAYCCNACNCCNTCNGGNTGGATHCCNCCNAAYGAYGTNYTNMGNTCN CARCARTCNTTYYTNGTNMGNMGNACNAARAAYCAYGTNYTNCCNGTNTAYGCNCARCAR ATHGARAAYTGGGGNMGNATGATGCAYCAYGTNATHATHAARAAYATHGARGGNGAYATH TGGAARYTNGARTCNGARYTNMGNCAYCAYYTNCARGAYCARACNGGNGARAARAARATH ATHACNCARGTNCAYGARGTNAGYMGNTGYATHMGNATHMGNGGNCARCAYMGNGCNACN ATHGCNGARTTYYTNATGGARMGNGGNATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CCNTAYYTNGTNTTYGAYATHATGGAYGGNTTYGARAGYTCNGGNAAYGCNAAY TCNAARAARAAYGARAARGARGCNAARTGYGTNGTNCARYTNTGYAARTGYGTNYTNMGN YTNTTYTCN---AARAGYAARGGNAARAAR---------YTNAARAGYATHGGNATHATH TGYCCNTAYACNGAYCARMGNCARGARATHAAYAARATGYTNCAYMGNCAYGGNGTNAGY AARGTNATGGTNAAYACNGTNGAYAGYTTYCARGGNCARGARAARGAYGTNATHATHTTY TCNTGYGTNMGNGCNCARGARTCNCCNCARTCNGTNGGNTTYGTNGGNGAYMGNAARMGN ATGAAYGTNGCNYTNACNMGNGCNAARTTYGCNYTNTTYATHACNGGNCAYTTYTCNACN YTNMGNAARTCNGARATGTGGGCNTAYYTNTAYAARGAYGCNMGNGARMGNGGNGTNYTN GTNGARGTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AGYGCNGARMGNAARGGN MGNYTNYTNAAYGCNATHGAYAARAARGTNCARYTNAARATGGCNTCNAGYCARYTNAAR GCN---------CARACNAGYCARATHCCNMGNTTYATGACNTTYYTNACNAAYAARAAR AARGARACNGARAARCCNACNACNCCNGGNAAYAARGAYTGGAARAARATHCAYAARAAR CARTTYTCNAARTTYGAYTCNATHGAYGTNTAYYTNGARAARAARCARCARMGNAARGAR AAYYTNACNTCNAGYTCNAARAARCARYTNACNTAYAARTCN------MGNCCNMGNTCN TCNACNGGNAARTCNAARAAYGTNATHAARGGNACNGAYAARCARACNGTNTTYAARCCN ACNGTNACNTCNACNAARAAYATHAGYTTYGAYTTYACNGGNTCNAARACNGCNTCNAAR CARAARACNGTNATGACNACNAARAGYATHAAYTTYGARTTYTCNACNTCNGAYTCNAAY AARACNCCNAARTCNAARTTYYTNAAYACNCCNTCNAARGTNTCNACNAGYACNACNMGN GGNACNCCNTTYAARTTYACNGGNAAYACN---------AGYACNYTNAAYACNACNACN AAYTCNTCNAARAARCCNGTNTTYGAYYTNAARGCNAGYYTNGCNAARCCNYTNACNTGG AARCCNCAYACNGGNAARYTNCARTCNATHGAYGTNAAY------ACNGGNCAYYTNGCN CCNGCNCCNAARTCNAGYGGNGTNYTNGCNAGYMGNMGNGCNMGNAARMGNAAYTCNATH ACNMGNAAYMGNCCNGTNCARGCNAARAAYGTNMGNMGNGCNGCNCAYYTNGAYMGNMGN AAYAAYCARAARTAYGTNGAYATGATGAARMGNMGNGGNYTNATG--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGAAYTTY GGNTCNGCNTTYGTNTAYACNGGNAAYAARAGYGARGAYGARGARGARGTNAARGTNATH GARGGNGAYGAYYTNATHYTNTCNGAYAGYGAYGTNAGYGAYGAYGAYGGNGARACNTGY YTNYTNGAYATHYTNGAYACNGCNGGNCARGARGARTAYTCNTCNYTNAARGAYCARTAY GTNMGNACNGGNAAYGGNTTYGTNATHATHTAYAGYATHACNGAYAARGARAGYTTYACN GARGCNGARGCNGTNTTYMGNTGGYTNAARMGNYTNAAR---GARGARGARTCNTAYGCN ATHYTNGTNGCNAAYAARCARGAYYTNAARGAYTCNGCN------GTNGTNAGYTCNGAY GARGGNAARGARYTNGCNAARAARYTNGARATHCCNTTYTTYGARACNTCNGCNAARGCN GGNACNGGNATHGTNCAYGCNATGAARGGNYTNATHMGNACNATHCCNMGNACNGGNAGY GAYTAYAARATHGTNATGYTNGGNAGYGGNGCNGTNGGNAARTCNAGYATHACNGTNMGN TTYGTNAAYGAYACNTTYYTNGARGAYTAYGAYCCNACNATHGARGAYTCNTAYMGNAAR ATGATHAAYGTNGAYGGNYTNACNGCNGCNAAYAARGARTCNMGNAARCAYGCNAARAAR GCNAARMGNGCNAARAARCARACNCCNGGNYTNAAYCCNTTYYTNGCNACNTCNGCNAAY AAYGGNTGYACNCCNYTNCAYMGNCCNGGNTCNGGNNNNAAYGAYAAYACNTAYGTNTGY CCNATGCARCARGCNCCNATGGCNGGNCCNTCN---------------GCNGCNTGYGTN CCNCCNCCNCCNCCNCARAGYYTNCCNAAYTTYCCNGCN---ACNAARACNMGNAARGAR AARAARACNGAYGCNAAYGTNGTNYTNATHTCNYTNGGNACNYTNGARCARGARCCNAAY YTNGTNACNGGNGAYCCNATHMGNTGYAARCARTGYGARGCNGTNYTNACNGARACNGCN ACNYTNGARTCNGAYGGNGAYAARAARATHTGGAARTGYGARTTYTGYGGNTGYGTNAAY MGNGAYYTNGARATHGCNGAYGARGARATHCCNAARGGNGAYTGYYTNGAYTAYATGYTN TCNCCNGCNACNGARCCNGARGTNAARGARGARGARGTNGCNATGGARGTNGAYGAYGCN AARAARAARACNACNCCNGGNGTNATHGTNTAYTGYATGGAYATHAGYTCNTCNATGCAR GCNGCNTGYAGYGTNCCNGARTCNCARGCNTCNTGGMGNCARGARMGNYTNGGNGTNCAR GAYCARAAYGTNATHTCNMGNYTNAAYTGYATHCARATGGCNGTNGARMGNYTNGCNGAR CARYTNAARAAYGARAAYCCNGGNAARAARATHYTNYTNGTNGTNTTYAGYTCNCARGTN YTNGTNAARGCNGGNGGNTCNYTNAGYAAYYTNAARAAYTTYAAYGAYGTNGAYAAYAAR TCNTTYGARGAYYTNYTNACNTCNGGNGTNGCNYTNTTYGARGGNTAYCCNYTNAARCCN YTNGARGARTCNTAYGARGARATHGTNGAYGCNGTNAARGCNYTNMGNACNACNGGNTGY ACNGCNYTNGGNCCNGCNYTNTCNATHTGYATGGGNTTYGTNAGYAGYATHCCNTCNTCN GARATHGTNYTNTGYACNGAYGGNGARCCNAAYGTNGGNGTNGGNAGYGGNAAYAAR--- GCNGCNTTYTAYGARAARGTNGGNAARTAYGCNMGNTCNAARAAYGTNACNATHAAYATH YTNGCNGTNGARGGNGGNTCNGTNGAYYTNGCNACNGTNAGYGCNGCNGCNGARCAYTCN GGNGGNACNACNAAYAARYTNAAYCCNGCNGARYTNGTNMGNCARYTNMGNACNATHGCN CARAAYGARGTNGTNGCNACNTCNGTNACNGTNMGNTTYYTNYTNCAYCCNAAYTTYGTN TTYGAYGARCCNGARTAYCCNAAYAAYYTNAGYCARYTNGARAARGARGTNGGNTCNGCN MGNAARGARACNGAYYTNACNTTYMGNTTYAARATGMGNGAYCARTCNAARACNGAYYTN ACNTCNGTNCCNTTYCARGTNCARATHATGTAYACNMGNCAYAAYGGNATGAARTGYYTN MGNGTNYTNAGYAARMGNAAYAARATHACNAGYTCNMGNAARGARATGGARGARAAYATH AGYGCNACNGTNATGAGYGTNTCNGCNATGAARACNACNGCNCARYTNGCNAARCARGGN AARGCNAARGAYGCNCARCAYATGYTNAARAAYGTNAARMGNATGGTNAAYMGNGGNGCN AARTCNAGYGARCARMGNGARGCNAARYTNGCNTTYAAYAAYGARGTNGARGCNTGGGAY GAYCARYTNACNTAYAAYAAYGAYATHTAYGCNGCNAGYGGNCAYTGYGAYYTNGCNGCN CARATGATHCARCARTCNAAYCARATGTAYGGNGCNMGNGAYGTNGGNGCNACNAARTTY GAYAARGTNATGGCNMGNAARAARATGAAYTCNAARGCNAARGAYGCNTAYTAYGTNTTY AARAGYGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNMGNAGYTAYAGYACNAGYGAYYTNACNAAYGAYGGNCARGGNGTNMGNCARMGNCAY CAYGCNYTNGARGARGARGARGTNGARGAYGARYTNGAYAAYMGNYTNMGNGARGAYAAY GCNGARYTNGARAAYMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CARYTNTTYAARGAYTTYCCNMGNAARMGNTCNYTNGTNGAYATGCCNGTNGTNACNACN YTNTAYTAYTGYTCNYTNTAYCAYTTYCAYYTNGCNGARAAYTCNYTNGGNAGYCCNTTY GCNGTNCARAARMGNCAYCARATGTCNGARAARCARTAYGCNTGGACNGCNATHAGYGCN MGNGCNAARYTNMGNCARTGGAARGAYATHGARAAYATHYTNACNACNAARGGNTGGTTY GGNGGNACNAARYTNAARGCNGTNATHGGNTTYGAYAARATHGTNGGNATHYTNCAYAAR AAYGAYGGNCCNCCNGAYATHYTNGAYAARTAYYTNGCNATGATGAGYGAYGCNGARGCN MGNYTNAAYYTNGCNAARAARGTNAAYTGYCAYAARGCNGTNATHGAYACNTAYACNGCN YTNAARGAYMGNGCNTCNYTNGARAGYTAYGCNTCNAARYTNGAYMGNTAYTCNAARGAY GGNYTNTAYGCNTAYGAYACNYTNAAYGGNTCNACNGTNAARTGGAARATHGCNGCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYCAYACNTCNTAYTCNGCNAGYGTNAAYCAY MGNAARGARMGNGCNATHGTNAARCAYYTNAAYTAYMGNAAYCAYGARAARACNATHAAR CAYTCNTAYAGYCCNATHGTNGARCARCCNGAYTAYACNTAYYTNGAYGGNMGNCCNACN GARATGACNAARTCNTAYAARGARAARCARGARAARAAYTAYAAYYTNGCNCARCARGTN GTNAARYTNGTNGGNGARGTNAARTTYGCNCARAGYCARYTNATHAGYGAYGARGARGCN AARGTNGCNTAYCARCARCARMGNCARAARTCNMGNYTNAARGARAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GCN GTNYTNGARMGNTCNCCNCARATHMGNMGNTCNACNCCNCARATHCCNTGYCAYAARATG GAYCCNMGNMGNACNTGGGCNCARGARGCNCCNACNGGNTTYTTYCAYAGYGGNAAYTGG CAYTCNYTNYTNTGYACNMGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGTCNATHGARATHGTNTCNAARTGYYTNGCNYTNGAR------GAYYTNGARGAYMGN TCNATHAARAGYAARAARAARAARAARCCN---AARACNAAYGAYGCNATGCARATHATH AARACNGAYMGNCAYGGNGTNTGGAARGARYTNMGNAARGARMGNAARAARCARYTNAAR CARATHAARGCNAARMGNAARAARGARATHTTYAARTCNGCNATHGARAARTAYAARGAY AARCAYGAYGTNGAYTAYACNGARAGYAAYGTNGARACNYTNYTNAARATHTCNAARYTN GGNAARGTNACNGAYGTNGAYGCNAARAARATHYTNTAYCARCARCCNTGYMGNYTNTCN MGNGAYGTNAARGARGARATHAARTCNYTNGARCCNGARTCNGTNTTYACNGARGARGAY TTYGARAAYTTYGCNAARGAYTAYAAYCCN---ATGTCNGCNCCNCCN------GTNAGY GGNGGN------------AAYCARCAR---------------------GAYMGNCARAAY MGNAARYTNYTNYTNGARCAYYTNCARGARCARAARAARMGNYTNCARCAYGGNCAYCAY TCNTCNACNATHAGYCCN---ACNCCNTCNATGAGYGCNAGYCCNGCNGCNATGYTNAGY AAY---CCNTCNTCNGTNCCNGGNYTNTCNGCNGCNGARTAYGCNACNATHAGYAAYCCN GCNCARMGNGCNGCNYTNCARCAYGCNCAYGCNAAYTCNGTNGGNTAYTTYATHACNCAR GAYTCNTCNTTYGGNAAYYTNATHYTNCCNGTNYTNCCNMGNATHTCNGAYGTNAARTCN GARACNAARGGNGGNTAYCCNYTNAAYCCNGGNCCNGAYCCNGTNCAYCCNGGNGGNYTN GCNAARGAYCARTGYGTNACNGCNCCNGGNYTNGAYGARGCNYTNTGYTTYGCNTTYMGN ACNGAYAAYTCNGGNCCNCCNAARAAYTTYCARGARATHYTNAGYAAYTAYGARATHYTN MGNGCNGARTTYCCNGAYGCNAARATHTTYGCNTCNACNTTYGAYAAYTTYGCNGCNGAR ACNTGYGCNAAYGGNCARTGYYTNTAYGAYGAYCCNYTNATHTTYAAYGCNACNMGNTTY YTNATGAARGCNCCNGARCAYACNTGGGGNGCNCAYAAYTTYYTNAAYAAYYTNGAYTGG TCNAAYTCNAARYTNGGNGCNGCNMGNAARACNAARTCNTTYAARACNACNGARGTNACN TGGCAYGARCARMGNCARTTYATHTAYYTNGCNCAYGAYGCNYTNGGNTCNCAYCCNYTN MGNGAYAAYGTNACNAARGCNTTYCARGARYTNCARACNTCNGARCCNGAYYTNATHGGN TAYYTNCCNGCNAARYTNGAYCARGARTAYACNTGYTCNGAYGGNGCNGTNATHCARTTY GCNATHGAYGGNTCNYTNATHMGNYTNTAYGAYCCNGTNCAYCARGTNGARTGGGCNTCN CCNGAYCAYCCNYTNGGNCARGTNACNTAYCARACNTTYGTNGARCARGAYTTYAARGAY ATGCARMGNCARTAYYTNTAYCAYGCNGGNGTNGGNTAYGAYAARCCNAAYYTNACNGCN AAYGCNCAYCCNGARAARAARCAYTGGCCNATHGGNGTNATHMGNTAY---ATGAARAAY GAYAGYAARTGYGAYTTYTGGYTNGARATGAARATGTTYGAYATHGARACNGGNYTNAAR TAYGGNGCNCCNTCNAGYTTYTAYYTNCAYTAYCARTCNGTNCCNGCNGTNGGNYTNGAR GTNGAYGTNYTNGTNATHAAYAARGTNACNACNMGNYTNCCNGARTCNATHTCNTTYCAR TTYACNCCNMGNACNCARGGNATGAARTGGGGNATGAGYAARATGGGNMGNYTNGTNGAY CCNTGYAAYGTNGTNYTNAAYGGNAGYCARTAYGTNCAYGCNGTNGAYACNGGNGTNAAY YTNACNGAYCCNAAYGGNTAYGGNYTNTAYYTNAGYGCNYTNGAYTCNCCNYTNGTNCAR TGGGGNACNTAYGAYMGNGCNCCNTCNCCNTTYCCNGTNCCNYTNCARCCNYTNAAYTGY TCNACNYTNACNTCNGTNGCNTTYAAYYTNTAYAAYAAYATHTGGAAYACNAAYTAYATH TAYTGGTAYCCNTAYTCNACNCARGAYGCNAAYTTYACNTCNMGNTTYAGYYTNTAYTAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARMGNCARYTNGARATGMGNMGNCARAARATHGAYGAYYTNMGN AARMGNGAYTCNGARMGNMGNGCNGCNGTNGARGARMGNMGNMGNATGAARGARGARATH GARMGNYTNMGNAARGARTCNATHYTNCARAARGCNGARGARMGNGTNGCNMGNTTYGAR GCNTGGMGNGCNGGNGGNMGNAARGGNAAYYTNGGNGGNGARGGNAGYACNCCNMGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATHAAYTCNAAYGGNCARYTNYTNGARTCNCARTCNCCNTGGMGN YTNTCNTTYATHACNGARGCNATHTGGGGNATHATHAAYTTYATHGTNYTNTTYTTYCAR ACNYTNATHAAYCCNAAYAARAAYAGYAARGGNGARAAYTAYACNTCNGAYTAYMGNMGN CCNGGNGGNGGNGGNCCNCCNACNMGNMGNATGGGNGGNTTY---MGNMGNGGNGGNGGN GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNTCNTAYGCNGAYYTNATHACNAARGCNATHCARAGY TCNCCNGARAGYMGNYTNACNYTNTCNCARATHTAYGAYTGGATGGTNCARAAYGTNCCN TTYTTYAARGAYAARGGNGAYAGYACNAGYTCNGCNGGNTGGAARAAYTCNATHMGNCAY AAYYTNTCNYTNCAYAAYMGNTTYATGMGNATHCARAAYGARGGNACNGGNAARAGYTCN TGGTGGGTNATHAAYCCNGAYGCNAARCCNGGNAARACNCCNMGNMGNMGNGCNGGNAGY ATGGARACNAARAGYTAYGARAARAARMGNGGNMGNGTNMGNAARAARGTNGARGCNYTN MGNGCNYTNGARAAYGGNGGNACNYTNTCNCCNAGYYTNAGYGARGAYTAYYTNGAYGCN TTYAGYGAYTTYMGNCCNMGNGCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATHGCNGTNCAYATGGGNACNGCNCAYCCNCAYTTYGARAARGAYGGNACNGTN YTNTAYTTYGGNACNAGYATGTAYTGGCAR---GCNTAYAAYATHATHMGNGCNACNCCN CCNAARTCNAAYGARGARCCNATHATHGAYGGNGARATHGTNGCNACNATHCCNAGYMGN TGGAARYTNTGYATHGCNTAYAAYCAYTCNTTYGGNGTNACNGARAAYTAYATHATHTTY ATGGARYTNCCNTAYGCNATGAAYYTNMGNAARTCNYTNACNATGAAYTGGTAY------ ---AARAGYTGYYTNGCNGAYTTYCCNAAYGARAARATHYTNATHTAYGTNATHAAYAAR AARACNGGNAARMGNCAYCCNATHATGTAYGARGCNCCNCAYGGNTTYGTNTTYCAYTTY ATHAAYTGYTAYGARGARATGGAYCAYATHGTNGTNGAYGTNTGYYTNTGYGAYACNGCN ATHCARGAYYTNTAYATHGARTCNYTNATHAARCAYAAYTAYMGNCAYAARAAYCARGCN TAYTAYGCNMGNTTYATHYTNCCNYTNAAYGTNAAYGGNGCNCARATHGGNAGYAAYGTN AAYAAYYTNTCNGGNAGYCARGCNAARGCNGTNYTNACNGAYTCN------GTNGTNGAY GTNGARCCNGARYTNACNTTYGGNAARTCNYTNAAYTTYGAYYTNCCNCARATHAAYTAY AAYTAYAAYGGNYTNAARTAYMGNTAYGTNTAYGGNTCNTGYTGYTTYACNACNACNTCN AAYAARATHATHAARYTNGAYYTNAARGAYAARACNTAYAARGARTGGATHTGYGGNGAR AAYTAYYTNGTNGGNGARCCNGTNTTYATHCCNCAYCCNGARTCNAAYAARGARGAYGAR GGNYTNGTNYTNTGYCCNYTNGCNTCNGTNGTNTCNGAYGARCARTCNTTYYTNGTNGTN YTNGAYGCNGARACNTTYGARGARYTNGCNACNGCNMGNYTNCCNMGNGAYGTNCARYTN AGYGTNTCNATHCAYGGNACNTTY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GCNACNGCNTAYGARCAYACN ACNGARAGYCAYACNGGNCCNCCNGARATHMGNGTNCAYCCNGARTAYGTNAARAGYGTN CCNGGNATHATGAARYTNGTNGARATHGTNYTNTGYATHYTNATHYTNATHTGYGCNTCN GTNGAYGCNTGGTAYCAYYTNGGNGGNGGNTGGGTNCARTTYGTNGCNGCNTCNGCNATG GTNACNACNTTYATHYTNTTYATGYTNCAYYTNTTYAAYYTNGTNCCNMGNYTNCCNGGN CCNTGGYTNTTYATHGARTTYYTNTAYTAYTGYGTNTAYTGYATHYTNYTNATHATHGCN GCNATHGTNTGYGCNGTNMGNGCNCAYYTNTAYGAYTCNATHGGNGCNTAYAAYTAYGAY TGYGGNGTNYTNGTNACNGAYTTYCCNTCNCARACNYTNGARAGYGARYTNMGNGGNGTN TTYAARGAYTTYAAYGTNYTNGAYATHTGYGTNATHAAYAAYGGNTTYTCNGARGGNTGY ACNMGNGCNATGGTNTAYATGGGNACNYTNTAYCARGCNGTNGARGTNATHCARAGYAAR MGNMGNTTYGTNYTNCAYGAYCAYACNYTNAARGTNATGTCNAGYGARGARGARGAYTAY ATGTCNGAYGCNTTYYTNYTNAARTGYGGNGAYGTNCARCCNGGNYTNGTNCCNAARGAY AARAARAARCARTAYCARMGNGARAARMGNGARAARGARGCNAAYCARGTNAAYAARATH YTNCCNMGNAARCARYTNGARAARCARCARMGNGAYGTNGGNYTNAGYACNGGNATHTCN AARACNAGYAARGGNTTYGCNYTNYTNCARAARATGGGNTAYAARCCNGGNACNGGNATH GGNAARTCNGGNGARGGNMGNGTNGARCCNATHCCNTTYGARATHAARACNGGNMGNTCN GGNYTNGGNAARGARTCNGAYATGAARMGNAARTCNACNGARATGAGYAAYATGMGNGCN GCNATGYTNGCNAARMGNAARAARCAYAAYGARAARCARACNGARTCNTTYAARACNMGN ATGAARGAYMGNTTYAAYGAYAARCARYTNGARMGNGAYYTNMGNATHGCNCARAARGCN TGYATHCARYTNGAYCARGARGCNGGNYTNGAYGARGCNCCNGARCCNTTYTTYTGGCCN CCNAGYTGYYTNTCNTCNYTNAARTCNGARGARAAYGAYGAYGARGAYGCNGCNAGYCAR GAYGGNGARGARTAYGTNACNGARGTNTAYGAYGARMGNTCNGAYGAYGAYGAYYTNGAR GARGARGARGARATHGARCARCCNGARMGNACNGARATHYTNACNTGYTAYYTNMGNAAY ACNTAYYTNTAYTGYATHTGGTGYGGNACNAAYTTYGAYGAYGARCARCARATGGCNTCN CARTGYCCNGGNAAYACNGCNGARGCNCAYGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GTNGTNMGNTCNGGNATGGCNGTNYTNCCNTGYTCNGTNAARGAYGTN GGNTCNMGNGTNGTNGTNTGGMGNMGNYTNAGYGAYGAYCAYTTYYTNACNATHGGNGAR MGNYTNTGGACNAGYGAYCCNMGNGTNATGGTNGAYTTYGAYGAYGAYGCNGCNGGNACN ACNACNTGGGAYYTNYTNATHAARGAYGTNCARTTYGARGAYGCNGGNGTNTAYGARTGY CARGTNACNTCNATHGARTAYYTNACNMGNCAYGTNGARYTNAARGTNTTYGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARGARTGYGARYTNTGYTAYGAR---AARAARAAR YTNGARAARYTNTTYTGYTGYGAYAARTCNATHTGYAARTCNTGYCAYAARAARGTNAAR MGNTGYCCNTAYTGYYTNAARATHTTYGGNATHYTNACNGGNGAYCARCCNCCNGGNGAR ATGGARGTNAARAARAAYAGYAAYATHATHYTNGGNCAYGARAARGAYMGNGGNTGYTAY GARATHAAYTAYGCNACNAARAARGGNTCNACNGCN------------------------ ---------------------------YTNTCNYTNYTNATGYTN--------------- ---------------GCNTTYAGY---MGNMGNYTNACNTTYACNMGNGGNATGTCNMGN ACNACNGGNAARGARAAYCARATHACNTGGAAYGAYATHCAYCAYAARACNAGYYTNAAR CARAAYCAYCARTTYGGNTAYCCNGAYGARGARTAYYTNAARMGNYTNATGTCNGARYTN AARGCNAARGGNGTNACNCCNGARAGYATGACNAARGCNGARAARAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TTYCARACNAGYGARGARGAR YTNTTYGGNAAYMGNTCNCAYAGYCCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGAYCAYCARTAYGGNATHGCNGTN ACNAAYAARTTYGCNYTNTTYATHGAYGARGAYGGNGAYCCNTTYGARTCNATHTCN--- ---------------AARAAYAARAGYAARAARGAYGCNGARAARAARGCNMGNGCNMGN CARMGNAARATGAAYGCNYTNACNGARGARAARCCNGCNGCNCCNGARAAYGARGTNCCN AARAARAARGARGGNGGNGAYAARCCNGCNCCNAARCARACNACNGARMGNGGNAARGGN ATHGTNMGNAAYMGNGARCCNMGNGARATHMGNGARAAYGAYGGNGAYAARMGNCCNCCN MGNMGNCARGGN------------------------------------------------ ------CCNMGNGARAAYAARGAYGGNMGNGTNGGNGAYGARAAYGTNCCNCCNGARTTY AARGAYMGNCCN---GARGGNGGNTTYAARAARMGNGARGAYMGN------GARGGNAGY GGNTTYGGNGGNGARMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNGGNMGNGGN GGNGARMGNGGNGGNTTYGGNGGN---GGNGARMGNGGNGGNTTYGGNCCNMGNGGNGAY MGNAARMGNGARTTYGAYMGNCAYAGYGGNACNGAYMGNACNGGNATHAARCCNGTNGAR AARAARGARGGNGGNGGNGCNTAYAAYTGGGGNAGYTTYAARGAYGAYATHGARGARCAR GGNCARGTNAAYCCNGCNGARGARTCNACNGAYTGGGGNAAYCARGARAARCCN------ ---------GARYTNAAYGAYAGYACNGARGCNGARAAYGTNAAYGAYGARGAYGCNCAR CCNCARCARATGACNYTNGAYGARTGGAARGCNATGCARACNCAR------AARGCNAAR CCNGARTTYAAYATHMGNCARGCNGGNGARGGNGTNGAYTGYGGNCARTGGAARAARGGN GTNGARTAYCARAARAARCAR---------GARAARTCNGARTCNGGNGARGARGAYAAY GARGARGTNGAYCAYGAYCAYCAYGGNMGN---GGNAARCARYTNGTNACNGAYATHMGN ATHACNTTYAAYGAYAAYCCNMGNMGNGGNMGNGGNMGN---MGNGGNGGNMGNGGNGGN ATGGARMGNGGNGGNGCNGGN------GGNGGNMGNGGNMGNGGNGGN---------GGN GCNCCNMGNGGNTTYGGNAGYAAR---AARGARGCNGCNCCNMGNTTYGAYGAYGARTCN GAYTTYCCNTCNYTNCAYAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GCNTTYYTNATHGTNGARGGNTTYACNATHTTYAAYCAYGGNCCNYTN GCNAAYYTNTGYGAYAARAARTTYTTYYTNCARGTNGAYGARAARACNTCNGCNGARMGN MGNTGYACNMGNATHTAYGAYCCNCCNGAYGGNCCNGGNTAYTTYGARGARATHGTNTGG CCNATGTAYYTNAARAAYYTNAARGARYTNGARGAYCARACNGAYATHGARTAYGTNGAY GGNYTNTTYGAYYTNGAYGTNYTNTAYCARGARGTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GTNMGNTAYAAR---GGNAARCARMGNATHAARGARGCNAARACNCAR ATHGAYAARAGYAARMGNTTYATHGCNAARAARGAYAARAARAARTCNAARTTY---ATH GARGARATHGGNGARAARAGYCARATH---YTNGCNGARAARCCNGTNGAYAAYGTNTGG GTNMGNAARTTYTAYCCNAAYCCNMGNTTYTCNATHGARGARGCNYTNAARAARCAYAAR GAYTTYGCNCARCCNGCNATGYTNGAYAAYYTNGAYGGNATHGCNTTYATGGAYATGACN YTNGAYTTYMGNACNAARAARCARACNAARTTYATGAARAAYATHAARTCNACNYTNYTN YTNCCNCAYMGNTTYCCNTTYGGNGTNCCNCCNTCNATHYTNGTNTTYTGYAARGARGAR GARCAYACNAAYYTNGCNYTNTCNYTNGGNGCNAARCAYGCNGGNAGYCCNACNGARGTN ATHAARATGYTNGARAAYGGNGTNYTNAAYCCNAARGAYTTYACNCAYGTNYTNGCNACN GCNGAYTGYGGNACNGARATHATGCCNGCNMGNTCNTTYYTNMGNGARAAYTTYCCNCAR AARGCNAARGGNAGYATGGGNACNGAYYTNAAYGCNATGTGGACNYTNTTYTTYTTYGGN CAYACNTAYGARTCNCAYAAYGTNACNGARTCNCARGGNAARYTNCARGTNCCNYTNGGN CARYTNAGYCARCCNGTNAARGARYTNGCNGAYAAYTTYGARGCNTAYATHCARTCNGTN TGYAARCAYMGNAGYGTNGCNYTNGGNCCNTTYATHCARTCNATHAGYATHYTNGCNCCN CCNTCNCCNGARGARTTYGTNGTNAARGTNGARGAYTAYGTNCCNGGNTAYACNAAYGAR GARGTNGAYTCNGAYGAYGAYGARGAYACN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TTYCAYGCNTGGCAYGGNYTNYTN ATHGGNATHGTNGCNYTNGTNYTNGTNGTNATHATHTTYATHTTYTTYMGNMGNMGNMGN AAYAAYAARAAYCARTGYGCNAAYCARGGNYTNCCNCCNCCNGAYACNATHATHGTNTTY ACNCARGGNCAYYTNGCNTTYGARAAYAGYGTNTAYACNGARACNAAYMGNAAYAAYYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARYTNCAYYTNATHTTYCCNACNAAR GAYAAYATHMGNYTNAGYYTNGARGGNTAYAAYGGNGGNGGNTGYGTNCCNTAYAGYATH MGNACNGCNTCNAARCARCCNTGGYTNACNCCNYTNYTNAGYCARTGGAARTCNGARGGN MGNGGNMGNTCNMGNGCNGTNCCNCAYATHAARTCNTAYACNMGNTGYTCNCCNGAYGGN ACNCARGCNGCNTGGTTYGCNGTNACNAGYGCNAAYYTNTCNAARGCNGCNTGGGGNGCN YTNGARAARAARGGNAGYCARYTNATGATHMGNTCNTAYGARATHGGNGTNYTNTTYYTN CCNGCNGAYTTYGGNTGYAARAAYTCNTTYACNGTNAAYAGYMGNATGGARCAYGTNATH GAYCCNGAYMGNAARGTNTTYCCNYTNCCNTAYGAYYTNCCNCCNACNACNTAYGTNAAR GGN---AARAARTCNGTNGARTTYTTYTAYGAYGTNGTNTCNCCNTAYTCNTGGTTYGCN TTYGARGTNATGTGYMGNTAYCARAGYMGNTGGAAYATHAAYYTNAARYTNAARCCNTTY TTYYTNGGNGGNATHATGCARGGNGCNGGNAAYMGNGCNCCNGCNATGGTNCCNAGYAAR GGNAARTAYATGATGAAYGAYGTNACNMGNTCNAGYCARTAYTTYGARACNCCNYTNAAY YTNMGNGARAAYCCNTTYGARTTYATGTTYGARAARGGNACNYTNAARGCNCARMGNTTY YTNACNGCNGTNGAYATGAARTTYCCNGARAARYTNGARGAYGTNTCNMGNGARTTYTGG ATGMGNGGNTGGAGYMGNGAYCARGAYYTNTTYGARGAYTCNAGYATHGCNGARGCNGCN ACNGTNGCNGGNYTNGGNCARCARGAYGTNCARGARYTNYTNTCNYTNGCNAARGAYAAR GARGTNAARGAYMGNYTNAARAAYGTNACNGARGARGCNYTNGARYTNGGNGCNTTYGGN GCNCCNATGATHGTNGCNAAYGTNAAYGGNAARAARGARTGGGTNTTYGGNAGYGAYMGN TTYCCNGTNYTNGCNCARATHYTNGGNAARATHGAYAAYGGNYTNTGGAARYTNTGYTTY TCNGAYAARYTNGTNCCNAAYGGNTGYAARACNTGGGAYGAYAAR--------------- ------------YTNAAYCCNGGNGAYTGGYTNAARGGNGCNCARGCNATGGCNGTNYTN GGNGCNATHGTNATHGCNGGNGGNGCNATHYTNTCNGGNATHAAYYTNGTNGTNGARAGY MGNGGNGAYMGNYTNMGNATHYTNCCNATGATHATHTGYGGNGTNTGYTGYTTYGGNGGN YTNYTNACNYTNATHGGNGCNGTNATHGTNGCNGCNGARTAYAARAGYGARYTNGAYYTN CCNAAYGCNGTNCCNYTNTCNCARGCNGTNAARGAYATHYTNGGNMGNCARTTYTAYYTN AAYTGGGGNTTYGGNYTNGAYATHGTNGCNTTYGTNYTNGCNYTNGCNGGNGGNYTNGTN AAYYTNYTNGCNGGNGTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TAYGARACNATHTAYGTNACNGTNGTNTAYACNTTYYTNATGGTNTTYTAYCCNTTYGCN ATGCAYCAYATHCCNTAYTTYCARCARTTYAARGTNTCNAARGARGTNMGNTAYGTNAAY CARACNTTYATHGGNATGGGNATHGAYYTNGTNTTYCAYYTNACNCCNYTNYTNATHGCN GAYATGATHATHATHAARMGNTAYTCNGGNGTNCCNTAYTCNGARATHGCNATHMGNAAR CARGAYTGGATHGTNMGNACNMGNCCNYTNCCNGARGAYTCNCCNGARTTYATHACNYTN TGYTTYCAYGTNATHGGNAGYGTNGTNYTNTTYGAYYTNTTYTTYACNATHGTNCAYTAY GCNATGCAYMGNAAYMGNTAYYTNTAYAARTAYTTYCAYTCNCARCAYCAYGAYCAYGAR GTNGTNCAYGCNCAYGTNACNAAYCARYTNTCNGTNGTNGARMGNGCNYTNCARGTNATH TCNGCNAAYTAYGCNYTNAARGCNTTYGCNTGYCAYCCNYTNACNMGNYTNGTNTTYGTN CCNGTNTTYYTNTGGYTNYTNATHGARAAYCAYACNGGNATHGAYYTNCCNTGGGGNCCN CAYMGNYTNYTNCCNGGNAARGTNATGGGNGGNCCNGCNAARCAYCAYGCNCAYCAYACN CARGGNTAYGGNAAYTAYCARCCNTTYTTYACNTAYATHGAYGAYTGGYTNGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR TGYYTNGCNTCNCAYTCNCCNYTNYTNGAYACNTAYAAYATHCCNACNTAYYTNGCNCAR CARAGYTCNATGCCNGGNATHGTNCCNGCNTTYAARMGNATHGCNATGGGNGARGCNATG GGNAARGGNGGNATHCCNYTNTAYCCNAGYAAYCAYYTNATHTCNCCNCARCARCAR--- ---GCNTCNYTNGTNCCNYTNCARCARCAYCCNTCNTAYATHCCNATGCCNTAYCARYTN TCNTTYCARCAYCARATHGCNGGNCAYCCNCCNAGYGTNCCNMGNTTY------------ ------------------------------------------------------ATHATG GAYTCNTCNGTNGTNATHYTNAGYCCNACNGAYGAYGTNGGNCCNATHMGNMGNMGNMGN GGNAGYGGNMGNMGNGGNGTNMGNMGNTCNMGNCAYCCNCARACNGAYMGNAGYYTNTAY YTNTCNCCNCCNYTNAAYATGCCNTCNTCNTCNGGNACNGCNCARCARGAYGTNGTNGTN GARAAYAGYGAY---------GARGARYTNCCNGAYATHCCNTTYGARATHTCNGARGAR AGYTCNGCNGCNAAYTCNGAYYTNCARTCNCCN---CCNYTNAARATHACNTGYCCNGTN TGYYTNGAYGAYYTNAARCARATHAARAGYAGYAARMGNMGNGTN--------------- ------------------------------------------------------------ ------------------------------------------------TCNTCNTCNCCN GCNYTNAARGTNTCNGAYCCNGAYTCNTCNGTNACNYTNTCNCCNMGNGARAAYTAYAAR ATHAARMGNCARAAYMGNAGYAARACNYTNCCNGTNGGNAAYACNGARACNGAYGAYAGY TCNCCNAARGTNCARMGNGTNGCNTCNCARMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AAR---------------------------------------------TCNMGNAAR GARYTN---------------------------------TTYGCNCCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CAYMGNGGNACNYTN GARTTYATHCARCAYGCNGCNGGNTGYGAYGGNCARTTYCCNACNTAYTGGAARCAYCAR AGYTCNAGYGTNAGYTTYCARGGNGGNAGYTAYATHGAYGTNAAYGARAARACNAARAAR GCNATHACNGAYYTNGTNTCNAARACNTGGGAYGTNAARAARGTNGGNMGNGGNAAYGAY GCNACNGGNATHCCNYTNAAYTCNAAYATHCARGTNGARAAYGTNCARMGNGTNGARAAY GCNGAYATGTTYYTNMGNTAYTTYGGNATHMGNMGNAGYATHYTNMGNGAYATGGCNATH MGNAARMGNGTNTGYGAYAARGCNGCNAARYTNCARGGN---AGYGCNGGNGGNATHATG ACNATGGAYTAYYTNAGYCARTCNATGAARAARGARYTNYTN---CAYGARGTNAAYGAR TGYTAYYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AGYGAYAGYAGYGGNGAYGARGCNGGN MGN---ATGGCNAGYGARGARGARGARCCNYTNATHCAYCAYCCNTTYAARGTNAARGAR CCNTCNACNAAYATHATHATGAAYATHMGNAAYGCNAARCARATHCCNGTNATGACNCCN TCNGARAARCARGCNCARCARTCNACNYTNMGNYTNGCNTTYCCNGTNTCNAGYGGNTCN CAYCAYMGNGCNAGYGARGGNGARTGGGTNCCNGTNGAR------------------MGN ACNACNGCNCARGCNGCNTCNACNACNAAYACNAGYACNGTNGCNCARGTNTCNGCNAAR CARCCNGTNGCNTCNCARAGYATHTTYCCNGARGTN---CCNAARGTNGAYATHGGNTCN ATHATHTCNGARMGNYTNCARGCNGTNMGNAARYTNCARAGYAAYCCNTAYGAYGTNCAR GCNYTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNAARCARTTYCCNAARGTNGCNGAYATHCCNGAYYTNATGAARGTN TTYMGNACNGCNTGGTTYGARAARYTNMGNGARGTNAARMGNGCNGARAARMGNGAYGAR GARTTYATGAARGARACNTTYMGNCARGTNTTYYTNGARTCNGTNTAYCCNYTNCAYCAY YTNGCNACNATGTCNGCNTAYAARATGGGNGAYGARGARAAYGAYAARGTNMGNCAYGAR AAYGTNATHMGNTTYAAYGARACNMGNMGNGTNAAYAARAGYGCNYTNGCNTCNYTNYTN TCNCCNGAYYTNGTNTTYAARCCNYTNATHYTNGARGARGTNGCNTAYTCNATHATHGGN CCNAAYTGYYTNAGYAARGCNCARACNGCNYTNGTNGTNCARGCNGARGARYTNGGNTGY GARGGNAARGTNGARGARGCNCARGGNGTNATGAARYTNGTNGAYCARYTNAARGARGAR MGNYTNGARYTNGAR------TCNAARCCNGTNAAYGARGAY---GGNCCNYTNATGAAR CARATGGARGTNTGYGARGTNTGYGGNGCNTTYYTNATHGTNGGNGAYGCNCCNCARMGN CARGAYGARCAYYTNATGGGNAARCARCAYGCNGGNTAYGCNCARGTNMGNGCNGARATH GAYMGNMGNAARGARAARGCNMGNGAYGARYTNGARGCNMGNGARGCNTCNGARAAYAAR ATHAARCARGARMGNGARGAYMGNGARAARGARMGNCARMGNGARMGNGARGARMGNMGN CARAARGARMGNGAYGCNGARAARMGNMGNGARMGNGAYMGNGAYMGNMGNMGNMGNAGY MGNTCNMGNAGYMGN------------GAYMGNGGNAARGAYMGNMGNMGNTCNMGNMGN MGNMGNMGNAGYTCNAGYMGNGAYMGNMGNAGYMGNMGNAGYAGYAGYGGNAAYAARGAY MGNAARMGN---------AGYTCNAGYMGNGGNAARMGNTCNMGNMGNTCNTCNAGYMGN GAYMGNAARCAYGARAGYAARMGNTCNMGNGAYAAYAAYTCNMGNAGYMGNGGNGGNTCN MGNGAYMGNAARGGNMGNAGYMGNGAYAARGAR---------AGYGARMGNAAYGGNGCN CAYAARGARGAY---------------------------------------ATGATHACN GAYCARTCNYTNGTNTTYGAYTGYCCNATGGCNTTYYTNAAYATGGTNTCNTGYCAYTTY AARGGNMGNAARGGNTCNAAYTGGMGNAARYTNYTNGAYYTNTAYGGNTGGACNTAYAAY GAYATHGAYYTNTTYTCNMGNCARCAYGARGARGARGAYTAYTTYGTNTGYATHYTNAAY GTNMGNGARTTYCARGAYTAYACNATHGCNACNYTNAARMGNGAYYTNAAYGAYATHCCN AARATHGAYACNYTNACNAARGTNCARGARTGGATHACNGARTGGAAYATGGAYTTYGAY TCNTCNGCNAARTTYATHGCNTCNYTNGCNMGNTTYYTNCARTCNYTNTGYAAYGGNTAY GTNGARTTYGAYAARGGNGTNGARGTNATHGGNCAYATHTAYYTNAGYGTNGAYAGYGAY ACNGGNMGNAARATHGAYTAYGTNYTNAAYGARAARGTNTGYAARAAYGAYAAYTCNGTN ACNTTYATHAGYAAYAGYTTYCAYGCNCARCCNGCNGARAARCCNAARCCNGTNCCNAAR TCNTCNAAYTCNGAYAAYMGNAAYGARGAYTCNGTNGTNATGGAYGAYTCNGGNCARTCN GTNCCNAGYAGYTCNAAYGTNGGNACNGTNGGNTCN---------------TCNTAYGAY AGYTCNGCNTCN---TCNAAYAARMGNCCNMGNTCNCCN---CCNMGNAARATGGGNATG GGNMGNGGNTCNGGNGGNCCNATHTCNAARTCNCCNMGNTAYCARGARTCNTCNGGNCCN AGYAAYCCNGGNYTNTCNGAYATHCCNAGYACNAAYAAYAGYTTYAGYGGNGCNGARGAY TAYGAYAAYTCNTAY------GGNGGNGAYGAYGAYAAYCARAGYTAYTCNTCNAAYTTY YTNAAYCARGAYTAYGCNAAYTCNGAYATHGTNGAYCARAARCCNGTNATHGAYCCNGAY ATHAGYATHGTNAARGARGARTAYATGTCNAGYCARCARCARAGYGGNGCNTAYTCNAGY GGNAGYCAYCCNTCNGGNCARGGNMGN---GGNMGNGCNCCNAGYTCNTCNCARTCNTAY TCNYTNGGNCARCARAAY------------------------TCNCARGCNTAYTCNACN GGNGAYTAYTCNGGNACNTCNATHGARCCNMGNGAYCCNTCNGARYTNACNCCNTCNCAR MGNGARGARYTNGARATGTAYTAYMGNAARGGNACNGAYCARCAYYTNACNTTYYTNMGN AAYATGMGNGARGCNCAYGCNATGTAYCCNTTYACNGGNAARMGNGAYAARGARYTNTTY GAYAARGCNYTNGCNGARYTNNNNAARMGNCANCCNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNMGNCARGCNGGNCARTTYAARTCNCCNGGNCAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TTYAARTGGGAYGGNTTYTCNGAYYTNCCNMGNTTYYTN ACNYTNGCNAARCARGARGAYYTNGTNGTNYTNYTNMGNYTNGGNCCNTAYATHTGYGGN GARTGGGARTTYGGNGGNATHCCNGCNTGGYTNYTNACNGAYAAYCCNGAYATGGTNTTY MGNACNAGYGAYCCNTCNTAYATGAARTGGGTNMGNYTNTGGTAYCARGARYTNYTNCCN AARATHAARCCNTTYYTNTAYAARAAYGGNGGNCCNGTNGCNATGGTNCARATHGARAAY GARTAYGGNAGYTAYTTYGCNTGYGAYMGNGARTAYACNYTNAGYYTNMGNGAYATGGTN GTNAARGCNYTNGGNACNGAYGTNGTNATHTAYACNACNGAYGGNGCNGGNGAYGGNTAY YTNAARTGYGGNAARGTNCCNGGNCCNYTNGTNAAYTCNGARTTYTAYACNGGNTGGYTN GAYCAYTGGGGNAGYAARCAYTCNACNACNCCNATGACNAGYGTNGCNAARAGYYTNGAY YTNATHYTNGCNTAYAAYMGNTCNAGYATHAAYATGTAYATGTTYATHGGNGGNACNAAY TTYGGNTTYYTNAAYGGNGCNAAYGARCCNTCNTAYCARCCNGTNCCNACNTCNTAYGAY TAYGAYGCNCCNGTNTCNGARGCNGGNGAYATHACNYTNAARTTYTAYGCNGTNMGNGAY ATHGTNTCNAARTAYYTNCCNYTNCCNTCNTCNCCNATHCCNTCNAAYACNACNAARATG AAYTAYGGNAAYGTNCCNATGAGYTTYGTNAGYACNGTNCARAAYGCNYTNMGNTTYYTN ACNCCNGARGGNCCNGTNAARTCNMGNTAYCCNGTNCCNATGGARACNATHAARTTYTAY GARGGNTTYATHYTNTAYMGNCAYATHYTNGCNAGYGAYTGGGTNAARCCNACNCCNYTN CAYAGYTGGGGNGTNMGNGAYMGNGCNATGGTNATGGTNAAYGGNGTNCCNTTYGGNATH YTNAGYMGNGAR---GTNACNACNGTNAAYATHACNGGNTCNAARGGNCARGARYTNGAY ATHYTNGTNGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MGNCARTTYGAY GTNAGYTCNGGNAAYCARYTNGTNGARTGYCARGARTGYCAYAGYYTNTAYCAYCARGAR TGYCAYAARCCNCCNGTNACNGGNCARGAYGTNMGNGAYCCNMGNTTYGTNTGGTAYTGY TCNMGNTGYACNAARAGYTTYAARAARATGATGGCNCARAARCCNGTNAARTCNAGY--- AARCCNTCNCCNGTNGTNTCNTCNAGYTCNAARGARCCNATHCCNTCNATHGCNAARATH AGYAARTCNGAYCCNGAYTCNAGYAGYCARGCNTTYMGNAARATHGAYCCNAARACNATH GTNACNCCNAARGAYACNAGYAAYYTNACNTCNTTYTCNAGYGCNATGGTNGGNYTNGCN GGNYTNGCNGCNAAYYTNACNAARCCNMGNGGNGAYGCNMGNAAYCCNGCNAGYAGYAAR AARTCNGARGGNAARAGYGAYAGYAGYAARTCNAGYAARTCNGAYATHAAR--------- ---------YTNACNGGNTCNAAYAGYGCNAARCARGAYAAYGTNACNAARCARTCNTCN TCNTCNTCNGGNAARAGYGAYAGYMGNAARGCNGARGCNGTNAARTCNTCNAGYAARGAR GAYCARMGNGARGGNAARAARTCNGAYTCNAARAGYAARACN---------------GAY GARAARAARTCNTTYGARTCNTCNTCNMGNAARGARGAYMGNGARAARGARMGNAARGAR MGNGAYAARGGNGARGCNCAYGGNAARTCNTCNAARGARGAYTCNTCNCCNTCNAAYTCN MGNTCNTCNAGYAAYTCNCCNCCNTCNACNCCNAGYACNGGNACNGARATGATGTCNACN AARAGYAGYGGNAGYAGYAGYAGYAGYAGYAGYAAYAARCARGCNGTNGCNAAYYTNTCN ATGGTNACNGCNAAYAARMGNATHCARATGATGAARAARAARGCNCARACNAARCCNYTN GARAARAARGCNTCNTCNAARCCNGTNACNGTNAAYAARCCNYTNACNCAYATHACNACN TCNMGNCCNMGNGCNCCNAARACNGTNMGNCCNTCNMGNCCNATHYTNAAYACNGGNACN ACNGARATGGARAGYCCNCCNAARATHACNATGAAYCCNMGNGAYCAYGCNGTNMGNGAR AARGARACNGTNAGYTTYTTYTGYCARGCNTCNGGNAAYCCNACNCCNACNTTYCARTGG YTNAARGGNCARACNMGNYTNMGNTTYAARAARGAYMGNTAYGARGTNCAYAAYTCNCCN CAYATGTCNGCNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AGYAARGGNYTNATHCARATHAARACN GCNGAYGARAGYGARGTNCAYMGNMGNATHGARTCNTTYATHMGNAAYAARMGNAAYGAR GTNAAYGARMGNAAYATHMGNGARTTYATHTCNCCNTTYGGNTCNGAYCCNGARTAYAGY TGYGCNMGNGTNGARGCNGTNTAYGTNMGNMGNGARGGNACNAARAGYCAYATHAAYYTN AARAGYGTNGAYAAYATGTAYGGNCCNCARACNMGNYTNMGNCCNGAYGGNGGNGAYGAR AAYYTNCCNTGGATGAARTCNGCNGAYGTNCARMGNGCNGARGCNGTNGARGARMGNYTN YTNAAYATGGARATGCAYATGAAYATHTCNTCNGAYAGYTCNAAYATHTTYAARMGNYTN AARGCNYTNGARGARMGNATHAGYTTYYTNGARGGNGTNTCNCCNGARTAYTTYACNAAY GGNYTNCCNCCNAAYAGYTTYAARACNCAR------------------------ACNATH GTNCCNACNAARCARACNACNGCNGAYATHCARGGNCAYTCNACNGAYATHGTNGTNAAY AARTTYGARGAYAAYYTNTTYATHATHGTNACNCARTAYAARAARYTNGGNACNGTNGTN GARGTNACNMGNGAYGTNATHAGYGAYGARGTNCARGGNCARGTNCCNATGTTYTCNACN MGNGTNYTNYTNGGNAARGAYGARCCNYTNACNCAYGTNATGGCNAARACNATHGTNAGY GCNYTNAAYCCNCCNGTNCCNGTNGTNYTNTGYYTNGCNYTNAARGTNACNACNTCNGAY GCNGTNCARTCNATHACNCARYTNATHCARTCNTGYYTNATGGCNAAYAAYATHCAYTTY GARGCNMGNMGNMGNCARATGTTYYTNGAYMGNGTNTGYCARGCNAARAARGAYATGTCN YTNTCNCARGARTCNGGNCCNGTNACNACN------------------MGNGAYCCNGAR MGNATHATGTGYACNGAYCARGGNCARTTYTAYCARACNMGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNTCNCCNGTNYTNMGNTAY CAYYTNAARYTNGAYATGTCNCAYTAYMGNATHGTNGGNCCNGGNACNTGGGTNACNGCN TCNACNAARGCNAARGARYTNAARGGNAARGARYTNACNYTNCARAARMGNATGCCNAAR TTYTAYGARGAYATHGARGARAARAGYCCNAARCCNAARYTNGCNTGYGARGGNATHMGN GAYGAYYTNYTNGARTGYYTNYTNAARAGYGAYTGYTGYAARAARGAYAARAAYACNCCN MGNGARTGYATGAAYAARATHGGN---------GAYCCNTCNGTNCCNGAYGARTGYCAY AARYTNMGNGTNGCNTTYYTNGARTGYMGNMGNTCNATGYTNGAYATGMGNACNMGNTTY MGNGGNMGNAARGARAARGTNAARYTNTTYGARGCNGGNGARYTNYTNGARAARYTNYTN GAYYTNACNACNTAYACNTTYYTNTTYYTNACNAARTCNTTYTGYGARGARCARTGGCCN TCNYTNGTNYTNCARGCNTGYYTNMGNAARATGATGTCNGAYCCNAAYACNATHATHCCN GTNCAYTCNATGTTYGTNTGYAAYMGNAAYTAYAARYTNCCNYTNTAYYTNGARCCNYTN AARTCNATHGARTAYYTNMGNAAYGAYCARTTYTAYAARGARYTNATHAAYGGNATGTTY TCNMGNAARGCNTCNGARMGNTTYGGNMGNGAYGCNGAYYTNAAYGCNMGNMGNMGNAAY TAYTTYYTN--------------------------------------------------- ---GCNATHATHGCNATGGTNGTNATHGTNTGYYTNGTNTCNGTNTCNATHGGNYTNTAY ATHTGYTAYAARMGNAAYAAYYTNACNACNMGNAGYYTNMGNGCNTTYYTNACNGGNGGN GTNMGNTAYAARACNTAYACNAAYGCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNYTNAAYCCNGAYTTYGCNGGNYTN CCNGARGAYTTYCAYMGNCCNGAYTGGMGNTCNGARTCNGTNCCNCCNTGYATHATGCAR YTNYTNTGYGARACNCAYGAYGGNYTNGTNGTNGARGCNAARACNATHAARGARCAYTGG TGGAARCCNCAYATHAARMGNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AAYAARGTNTTYGTNGCNGTNCAYACNGGNGCNGGNAAYCAYTCN AARGARAAYGARAAYCAYAAYAARAAYACNTGYMGNATGGCNTGYCAYCARGCNATGGAR YTNYTNCARYTNGGNCAYACNGCNGTNGARGCNGTNACNGTNGCNATHGCNACNYTNGAR GAYGAYGARAGYACNAAYGCNGGNTAYGGNTCNAAYYTNAAYATHCARGGNAAYGTNGAR TGYGARGCNTCNGTNATGGAYGGNCARTCNYTNTAYTTYGGNGCNGTNGGNGCNYTNTCN GGNGTNAARAAYCCNATHAARGTNGCNTCNYTNYTNGTNGARGARCARAARAARGGNCCN YTNCCNTTYGGNMGNATHMGNCCNAGYGTNYTNGTNGGNAARGGNGCNMGNACNTTYTGY ACNGARCAYGGNYTNGARGTNAAYCAYAAYATGATHTCNAARTCNTCNTTYAARACNTAY AAYMGNTAYAARMGNAARTGYCARYTNACNGARAGYTAYACNAAYGGNAARMGNAARAAR TTY------------------TCN------------------------AARGARGCNATG AAYGCNAARCCNAGYTCNGCNCCNGCNGAR------------------------------ AARTGYCARGAYACNGTNGGNGCNGTNTGYGTNGAYCARGARGGNAAYGTNGTNGCNGCN TCNTCNAGYGGNGGNATHTGGYTNAARCAYCCNGGNMGNGTNGGNCCNATHGCNATGTTY GGNGCNGGNTGYTGGGCNCARAAYAAR---ACNGCNAARAARGCNGGNGTNGGNGTNGTN ACNTCNGGNTGYGGNGARCAYYTNATGCAYACNGTNYTNGCNAARACNYTNGCNGAYGGN ATHMGNTCNTCNGAYAAYYTNTCNCARTCNYTNCCNCARGTNTTYAARACNGAYTTYATG GARTCNGARTTYYTNTCNACNACNYTNGARAARYTNGGNGGNGCNYTNGTNYTNAARYTN AAYCARGCNGAYAAYGTNACNGARGCNGARYTNTGYTGGATHCAYTCNACNGCNAGYTTY TGYTTYGGNTTYATGGGNGGNGAYCARAARACNCCNAARGCNGTNATGTCNCAYYTNGAR GARCARTCNATHCCNGGNCAYTCNTTYACNATGGGNGGNCAYATGGTNTGYYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GGNGCNYTNGTNTAYTCN ATGATGGAYTCNACNATHGCNAGYYTNTTYAARMGNAARACNAARTAYCARAGYAGYTTY YTNGAYGAYTAYYTNMGNGTNCCNTAYTGGAGYYTNGCNATHCCNYTNGCNTCNACNATG GCNYTNGTNGTNTTYGGNYTNGARTAYTTYGCNCCNTGGTAYACNGARGTNCCNGARTCN YTNYTNACNCCNGGNATHATGAARGCNGGNGCNTGGCCNCCNTTYTTYACNGGNATGYTN ATHGGNACNYTNCARATHCCNATHGTNYTNGCNGTNCARGAYACNYTNGGNTCNGCNTCN AGYTAYGTNACNGTNGTNGCNCARTTYYTNCCNTTYGTNAAR---------GGNGGNGTN GGNGAYGAYTAYYTNMGNAARTAYMGNTTYGGNATGAARAAYTGGTGGCARGTNYTNTAY GTNGGNGGNGCNGTNYTNGGNAGYTGGYTNTCNGCNAARGCNTCNGGNACNGTNGGNACN GTNACNGGNGTNCCNTTYAGYCARGCNTTYTTYGGNGGNTTYYTNYTNYTNTAYGGNTCN MGNYTNGCNGGNGGNTGYACNAGYGGNCAYGGNYTNTCNGGNATGGGNYTNYTNGCNYTN TCNTCNTTYGCNGTNGTNCCNGCNATGTTYGGNGGNGGNATHGCNACNGCNGCNTTYATG AARCAYTTYYTNCARGTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNCARCARAARGAYGARCARMGNGARGCNCARAARAARAARGTNGCNGAY YTNGARCARAARMGNGARAARCAYGARGARMGNMGNAARATGAGYCARAGYMGNATGGAR AGYMGNAGYMGNAAYTCNAGYCARACNGARCCNAGYGCNACNTCNTCNCCNGCNCAYTCN CAYGAYTCNTCNGAYGGNTCNMGNYTNCCNGGNACNYTNCAYGGNGAYACNGARGARGAR GTNATHTTYYTNGAYAGYGGNATHCAYGAYACNMGNTCNYTNGGNTCNGARAGYCCNATH ACNGTNMGNGTNAGYCCNGARMGNYTNCCNGCNYTNACNCCNGCNCARGTNAARGCNATH ACNGAYCCNACNCCNGARTCNGARGCNCAYAARTCNYTNGTNGCNAGYATHMGNTCNAAR GGNGGNTCNGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CARCARCARCARCARCARCARCAYTCNCCNAAYAGYYTNGCNGCNATHGGNTCNMGNAAY GTNYTNAGYGTNCARAAYCARGGNGGNCARCARAGYATGGTNAAYYTNCARAARMGNCCN TTYAGYGCNGCNGGNCCNATGCCNAAYTTYGCNTCNAGYTAYGGNTTYGGNGGNTCNGGN TCNYTNGAYTCNCARCCNACNATHGAYYTNTCNGAYTTYCCNACNYTNAGYAGYMGNTCN TCNGCNACNCCNAAYCCNYTNCCNTCNACNMGNAAYTAYGTNGGNATGGTNAGYAARCCN GTNCARGAYTCNGCNCCNGARTTYAAYATHTCNCARGARGARTTYCCNGCNYTNCCNGGN TCNCARAAYCCNCCNGTNCARACNGGNATGTCNGARTAYMGNGGNMGN---GTNMGNAGY AGYMGNGGNMGNGGNGGNCCNATHMGN---GGNGCNTAYMGN---GGNMGNGGNAGYTAY ---YTNGAYMGNGAYGGNGGNMGNGGNGGNGGNTTYMGNGGNMGNGGNGGNTTYTCNMGN GGNMGNGGNGGNCCNCCNMGNAGYMGNGAYGAYYTNTCNCCNCCNMGN------ATGTCN MGNAGYTAYGARTCNTCNGAYMGNGGNMGNGGNCCNCCNCCNAGYMGNMGNCAYGAYMGN TTYGARGAYAGYTTYGAYMGNGGN---CCNTCNATHMGNGTNAARGAYYTNTAYTCNTCN CCNCCNMGNGARTCNACNMGNAGYTTYGAYMGNCAYTCNCCNCCN------CCNMGNMGN GARMGNGAYTAYCCNCCN---MGNCAYAGYGAYCAYCCNTCNAGYMGNAGYGAYTAYATH CCNCCNMGNACNTAYTCNCCNCCNMGNGAYACNGGNTAYAGYTCNTCNTAYAARGAYTCN TAYAGYTCNGGNCCNMGNGARGAYMGNMGNCCNGTNMGNGAYTAYTCNTCNMGN------ ------------ACNAGYGARTAY---GARMGNMGNGAYTTYMGNGAYACNCCNMGN--- GAYTAY------AGYTCNMGNGAYTAYCCNCCN---TCN---MGNAAYGGNGAYTTYMGN GTNTCNGTNAGYAGYMGNGAYTTYMGNGAY---GCNCCNMGNGAYMGNTTYAGYAGY--- ------------AGYMGNGGNAGYMGNGGNMGNTCNMGNYTNGAYGAYMGNGGN---CCN CCNCCNMGNGARTAYGGNGGN---------GARGAYCAYGAYGAYTTYMGNMGNGGNMGN GGNAGYMGNGAYGAYMGNGGNMGNGGNTTYATGAAYGGNTCNMGNGGNTCNMGN---GGN GGNCCNMGNGGNMGNGGNMGNGAYTTYTCNGGNAGY------------------------ ---------------MGNATGGAYMGNMGNTCNTCNAGY------------------MGN GARGGNGCNGGNGGNAARMGNCCNMGNYTNGAYTCNGGNGAYTAYMGNMGNTCNATH--- ---YTNGARACNAGYGTNATHMGNGAYGCNGAYTGYGARMGNGTNTTYAARMGNTTYACN TTYAARTGYYTNCARATHATHGTNCARTCNMGNATHGARMGNCCNGTNYTNCARGGNAAR GAYACNACNAAYGAYTAYTTYAGYATHAAYYTNCCNGAYAGYCCNTCNATHGAYGARCAR ATHAARCARACNYTNGARGGNATHMGNTCNTAYCCNATHMGNGAYAARACNATHTGYGTN GARATHGCNYTNMGNACNAAYGAYGGNGAYCAYATGTTYYTNGARACNTGGGAYYTNAGY TTYAGYYTNAGYAGYYTNGAYATGTCNGCNAGYAARATHCARCAYATHTTYACNMGNATG GGNYTNACNYTNAARTCNYTNYTNTCNGCNACNMGNGCNGTNCCNGCNTAYMGNYTNGCN MGNAAYCARGGNGARAARGGNGGNGGNTAYAARYTNAAYTAYMGNTTYTAYYTNGGNCCN CCNAARACNCAYYTNYTNGGNGARGAYTAYAARACNGTNMGNGCNGGNGCNYTNCCNTCN GCNTAYGGNYTNYTNAGYATHACNYTNGCNTAYMGNACNAARYTNYTNYTNTCNCCNGAY ACNTCNTCNTCNTGYTCNAGYATHATGCARGTNACNGAYAAYCAYTTYATGAARGARCAY GCNGCNAGYGGNCAYMGNCARCARCCNTCNGARCCNAARCCNTGY--------------- ---TAYTCNTCNTTYAARMGNMGNTCNTCNYTNTCNAGYCCNGAYTAYATGGCNGCNCCN YTNTAYTGYTAYTCNGTNTCNCCNTCNTCNCARGGNACNGARGARGAY---YTNATGTCN AARATGTCNGTNGAYAAYCCN------ACNTGGCCNYTNACNAGYATHYTNAAYATGGAR GARYTNCCNGARCCNGCNGTNGGNGCNTTYTCNGCNCARMGNCCNAAYGTNYTNAARGTN GARGARACNGAYYTNCCNTTYGARGGNYTNATGAARMGNAGYATHYTNGCNMGNMGNGAR CARMGNCARMGNCARGARYTNMGNGARMGNGARGARCARGGNGGNGGNMGNGTNGGN--- ------------------AARACNGCNGTNACNAAYGARGARGARAARGARAAYATGGGN GCNYTNCAYATGYTNACNAGYAAYCCNCCNGTNGARGARGAYTAYGTNATHGTNGAYCCN CCNTTYGCNTGYGAYGAYGAYCCNMGNGAYGTNAARTCNTTYYTNGGNGCNATGTTYMGN GCNCCNCAYYTNTAYGAYGTNTCNGAYATGMGNYTNACNGTNGAYGAYTAYYTNAGYGAY GTNAGYGARATGATGTCNMGNYTNGARGAYGAYATGCCNGTNYTNGAYGARTTYTGYCAR TCNGTNATHAAYTTYAAYAGYACNGARGAYGARGAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNTTYCARGAYGTNYTNATH---YTN GCNTCNTCNYTNTCNTCNYTNAARCARATHATHACNGCNTTYACNMGNAARYTNGTNCAR YTNYTNAAYGAYYTNAAYATHYTNGARAAYGTNGARYTNTCNCARGARTGYYTNMGNTGY YTNAARAAYTTYTGGTCNYTNTGYTCNAGYCARCARAARGCNATHTGYCCNGARCARCCN TTYGGNMGNTGGTGYCCNGAYYTNYTNGARACNGTNACNCCNYTNGCNTCNATGTAYACN GAYYTNTCNATHACNGCNCAYMGNGAYAARGARAAYMGNTCNGCN------TGGGCNAAR AARYTNTGYAGYTGGYTNACNTTYGAYYTNCCNCCNMGNGCNGTNAARGTNGCNYTNYTN GARGTNACNAAYCAYACNCARGAYGGNGCNGAYATHGTNGARCCNYTNYTNMGNAAYATH YTNMGNGARCCNATHGARGARAGYTCNAAYGCNGARTAYYTNYTNCAYTTYYTNYTNYTN ATGAARTGGAARMGNYTN---CCNAAYYTNGCNGAYATHGCNCARAGYTCNAARYTNYTN AARGCNCCNTCNACNTTYYTNCAYTGGYTNAARCARCAYTGGGCNCARGCNTCNGAYTAY ATHCCNGAYGAYAARAGYYTNMGNGGNACNACNGTNAGYGGNTTYYTNATGGAYYTNGAY GCNGAYGAYGTNYTNGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TGYGGNAARGGNCAYAARAAYMGNACNMGNGARTGYATGGGNMGNACNGAYGGNGGN AARTCNTGYGAYGGNAARGAYAARCARGAYGTNGARTGYAAYMGNAARCCNTGYCCNCCN ATHCCNMGNAAYTTYCARATGTCNGTNTGYGAR---AARAAYTTYACNTGYGCNAGYAAR AARATGTGYGTNCCNGGNCCNCARAARTGYGAYGGNGARGTNCARTGYCAYGAYGGNACN GAYGARATHGGNTGYATGGARGGNYTNAARYTNGGNGAYTCNGARCARCARTAYTAYGCN GARYTNTTYCARGCNTGYGAYGTNGAYGGNACNGGNAARATHACNGGNCCNAARGCNTCN GARYTNTTYMGNGCNTCNGCNYTNAAYGCNGAYATHYTNMGNCARATHACNGARYTNTGY GGNGCNAARMGNYTNGGNCAYTTYGGNMGNAGYCARTTYTAYATHGCNYTNAARYTNGTN GCNGTNGCNCARGCNGGNYTNCCNATHAARYTNGAYGCNYTNAAYCCNGGNAARGARATH TCNYTNCCNAARTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARTTYACNGAYGAYGARATH MGNGARGARYTNATHCARYTNGGNTAYCAYAAYGTNCCNCARGAYAARYTNGARGAYTTY AARMGNGAYYTNATGAARYTNATHTCNACNGARMGNAGYAARACNAAYTCNYTNAAYAGY AGYMGNAGYACNGARCCNAARCAYMGNCAYGCNCARCARGARGARYTNGARGTNGARGAY ATHGARTGYGAYGARAAYGCNAAYTTYTCNAAYCAYAARAAYCAYAAYCAY---GGNAAR CARTAYMGNGARGAYTGGTGYTAYCARGGNAARAAYGARAAYCARTCN------------ ------------------CAYGCNCARGARGCNCARCCNATGTCNACNCARYTNTAYGAY GTNCARMGNATGAAYMGN---------------ATGAAYGCNCAYTTYGAR---AAYMGN CCNGTNGTNTGYGGNACNAARAARAARAGYMGNTCNTGYCAYCARGAYATHATHTCNGAY GAYGGNTGYGARAAYAARTCNATGAARMGNAARACNTCNMGNAARACNGCNGAYGGNTGY MGNAARGTNGAYGARTCNTTYACNGAYAGYGARTCNGGNGTNTTYGARATHTAYGARMGN ATHAARAAYYTNGCNATGMGNGARTGYMGNTGYGGN---ACNCARGGNAARTCNGGNGAY GTNGARCCNCCNTAYMGNATHAARGGNAARGTNAAYAARTAYCCNTCNGTNATHAARAAR YTNGARCCNCCNCAYACNMGNAAYYTNGTNMGNACNAAYGCNTAYGARMGNCAYMGNATG TAYAARGARGGNTGGAARAGYMGNCCNCCNATHGGNGARGAYGAYMGNTTYGCNYTNMGN AARGCNATHCAYACNCARATGYTNCARTTYGAYTCNATHMGNATGAARGARAARGTNTAY GTNCCNAAYYTNTAYGTNCCNCCNCAYGARAARTCNMGNAARGAYGTNMGNTGGCARGTN MGNCARGCNTTYGARAARTAYGARATGCCNCARCAYGGNCAYTAYCAYGAYACNYTNACN AARGARAAYGARGTNYTNMGNTCNAARACNCARAARYTNCAYATGGCNAAYAARGARTGG MGNGAYMGNTGGGARCARYTNAARAARCCNAARGARGAYGARAAYATGGARYTNCARYTN MGNATGAARCARATGATGGGNGCNATGGAYCAYATGAARMGNGAR------------MGN GAYCARAGYGTNCARGARYTNCAYCARGTNAAYACNYTNAARAARGARATHGARAARTCN TAYTCNGTNYTNYTNAGYGGNAARCARCARGARAARATGYTNYTNGARAARYTNAARCAR GAYTAYGGNAAYYTNCAYCARGARAARMGNGCNYTNGARGTNCARYTNGARACNYTNAAR GAYAARGGNMGNCAY------CCNGARAGYGTNAARGGNAAYTCNGARYTNGARACNGAR YTNACNGTNYTNAARMGNCARGTNTCNGTNTTYATGGARGAYTTYAAYAARGARCAYGAR GARAARYTNTCNTCNGAYAARYTNYTNCARAARGARMGNGARACNAGYCARAGY------ ------YTNGARACNAARYTNAARAARGCNCAYACNYTNYTNAARTCNMGNGAYGARGAY YTNMGNMGNAARTCNAARAAYATHGCNGAYTTYCARTTYCARATHGAYGAYYTNAARYTN AARYTNGARGTNGARCARMGNMGN------GGNGARCAYCAYATHTCNACNCAYGAYCAY TAYTAYCARGGNATGYTNYTNMGNTCNGGNAGYCAYATHAARGGNGCNTCNMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARTAYAARTGYCCNTCNAAYYTNACNAGYMGNTTYTCNMGNYTNATHATHYTNGAY MGNYTNACNAAYACNTCNGAYTAYCAYYTNCCNTGGGGNAAYACNTCNATHACNTCNYTN ATHGAYCCNAARTGGMGNAAY------AGYGARGTNTCNGAYCCNYTNCCNGCNCAY--- ------CARGCNCCNGTNAARGARTCNAARGARATHYTNAARATHMGNCAYAARAARATG AARAARCAYAARYTNMGNAARYTNMGNAARMGNATGTAYTTYYTNTGGMGNAARCARAAR ATGAAYMGNAARGCNAARMGNGAYGCNGTNTAYTGGAARGARATHGARGAYATHAARAAR GARGGNGAYGAYTTYGAYGCNGARGCNTTYGTNAARGAYCARYTNCARAARGCNMGNMGN GGNGGNTAYTTYATHAAYGTNTTYGAYTCNAAR---TTYGCNGTNGCNCARGCNGTNTGY MGNACNATGGGNGGNTAYYTNGCNGARGTNGARGAYGCNGAYGARTGGGCNTTYGTNAAR GGNTTYYTNAARGGNACNAAYGTNYTNGGNGGNMGNGAYGAYATHGCNGARGGNATHTGG TAYTGGAAYAAYAGYGARMGNCCNYTNACNTTYGGNCCNTGGGGNCAYGGNGARCCNAAY AAYTCNGGNAAYGARGAY---TGYYTNGARATHGTNTTYATHMGNCCNACNTTYGCNTAY AAYGAYATHTCNTGYACNTCNAARGGNMGNTAY---------MGNYTNATHCAYACNATH YTNATHYTNYTNAARTCNMGNMGNAAYYTNATGGAYAAYGGNGARGGNYTNMGNYTNGTN TCNYTNATGATHTCNAARGAYTGYGAYGTNAAYGTNAARGAYTAYAARCAYAARTCNCCN YTNATGATHGCNGCNGARYTNGCNCAYGCNCCNATHATGAARGTNATHYTNCARAAYTGY YTNGAYTGGCARYTNTTYACNCCNYTNCAYATGGCNTGYATGAARMGNTTYAGYAARAGY GTNYTNAGYGGNGGNTGGTCNCARGTNTTYYTNGCNYTNCAYMGNGAYTCNAGYYTNMGN ATGTAYAARAARCARGGNGARTAYTCNCCNCARYTNACNATHATGATGAARGAYGTNTGY AARTAYTTYGCNTAYGGNGARTAYACNAAYGGNATGCCNGAYMGNCCNCARYTNCCNGGN GGNTCNTTYATHTCNCARYTNATGGGNATHCCNACNAARCCNAGYGGNAARTCNAARATH ATH--------------------------------------------------------- ------------------------------------------------CARGTNATGAAR ATHATHAARTCNGTNATGYTNYTNATHGCNGTNAGYYTNTTYTTYCAYACNGTNTCNATH YTNTTYGGNGCNCCNGTNTTYCARTCNGCNCCNGARACNTTYCAYTTYGCNATHYTNATG ACNGTNTGYATHGCNYTNCCNTGYTGYATHGTNTCNGGNCCNAARGTNGAYAARTGGATH GAYATHTTYACNAGYGAY---MGNGARCCNGGNYTNGARACNGTNGTNTAYYTNTCNAGY GCNGGNGCNYTNYTNGGNGGNTGGYTNGGNGCNATHCCNATHCCNYTNGAYTGGGAYMGN CCNTGGCARGARTGGCCNATHACNTGYTCNGTNGGNTGYATHTCNGGNTAYTCNYTNGGN YTNTTYGTNGCNTCNYTNTAYYTNCCNCAYGARTAYAARTCNYTNTTYAARCCNAARYTN TTYYTNGTNGTNCCNGGNAAYCCNGGNGTNCCNAARTAYTAYGARGAYTTYATGAARGAR YTNTAYAGYCARTCNGGNGGNMGNATHCCNGTNTGGGCNGTNGGNCAYGCNGGNCAYACN MGNCCNCCNGGNACNCCNATGAGYYTNAGYGAYGTNGTNGCNACNGAYGARAARACNTAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNTGGMGNCARCARACN ATHMGNGAYCAYGARYTNCAYGTNAAYCAYGTNGCNTTYMGNGGNYTNYTNTCNTTYACN GAYGARYTNGARAARGAYATHMGNCARAARATHMGNAARTGYAARTTYGAYACNTTYCAR GARTTYYTNGAYTCNTTYTAYCCNTCNGAYGARGARGTNGTNTAYGCNMGNMGNCAR--- ---AARTTYTCNTCNYTNTAYGCNAARTAYAARAARGAYTTYGARGCNATHGARATHYTN ACNYTNYTNCARGTNATHYTNCARCCNGTNATHGARACNYTNATHTAYCARGAYMGNGCN AARTGGYTNAGYGARCARGGNCARAGYCAYGTNGARATHYTNCCNGTNTTYGAYGARACN ATHTCNCCNMGNAAYYTNGCNYTNGTNGCNGTNAARACN--------------------- ------------------------TCNGCNMGNMGNYTNYTNGCNCARMGNYTNMGNAGY CARYTNGARTCNAAYYTNAARAAYATHTCNCARMGNTTYGAYATHYTNTCNCARGTNYTN TCNMGNCARTGYAAYGTNGTNATHGCNCARMGNATHMGNMGNTCNTAYCARATHYTNYTN YTNTAYMGNAAYYTNTAYGGNGARCARTAYYTNAARGARAARTTYMGNTCNCARYTNAAY AARATHMGNAARMGNCCN------------------------------------------ ------------------------------------------YTNYTNGCNGTNGCNTCN YTNTTYAAYTGGGARAARGARMGNACNGAYGARGARATHGARMGNTGYYTNGGNGARGTN GCNGCNGTNAAYAAYYTNTCNAAY---GGNGCNGTNACNGCNTGGGARCARGTNGTNGAY AARGARGAYTTYAARGTNTGGTGYMGNGCNGTNCCNAAYACNGARYTNTTYCARTAYMGN GTNYTNGGNCAYTTYAARGAYATHCCNGCNMGNGCNTTYTAYAAYACNCARGTNGAYGTN CAYTAYTGGAARGAYTGGGAYGCNCARACNATGGAYGTNAARATHGTNGAYAARGAYACN AARACNGGNTCNGARGTNATHCARTGGYTNTAYAARTTYCCNTAYCCNATGTAYCCNMGN GARTAYGTNTAYGTNMGNMGNTGYGTNGTNGAYYTNAARTCNAARGCNATGATHATHACN GCNMGNGCNACNGAYCAYCCNACNTGYCCNACNAAYAGYTCNYTNGTNMGNATHAAYACN TAYACNTCNCARATGGTNATHACNCCNTAYMGNAAYTTYGAYGARAAYGGNTTYACNTAY GTNATGTCNTAYTGYGAYGAYCCNCARACNAAYTTYCCNCCNATGATGTAYAAYTGGATG GCNAGYGCNGGNGTNCARGAYTTYYTNGARMGNATHCAYCARGCNGCNYTNAAYAARCAR GARAAR------------------------------------------------------ ---------------ATGYTNYTNMGNYTNAARGARGTNATHCARTGGACNMGNATGACN GCNYTNGARYTNATGTTYCAYYTNGTNTCNGTNYTNYTNTTYTCNATHYTNYTNGCNGCN AARATHGARGGNGAYATHTCNACNTCNTGGCCNGTNATHTTYTCNCCNYTNTTYGTNTGY GAYGGNYTNAAYGCNTAYYTNTGYGTNATHATHTTYGTNMGNCARTAYCARGARTAYGAR YTNAARCARGCNTGYYTNMGNYTNTCNAAYTCNYTNTCNGTNATHGCNYTNATHTTYACN TTYAARYTNYTNYTNTGYCARAARYTNGCNAAYGGNGGNYTNACNTGYTCNGARGTNTTY GCNCCNATHTTYGTNYTNTCNCARGTNTTYATGTTYMGNGCNTGYMGNATGCAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATHMGNYTNAAYGTNATGGCNGAYAARGTN GARCCNCCNCCNTTYGARAAYGAYGARAGYGARGTNAARGAYGARGAYGAYYTNTTYTCN GAYGCNAARGARAARCCNTCNTCNCCNGARACNGCNAGYCCN---GARTCNACNGTNAAY GGNACNCCNGAYGARAAYGGN---AARGAYGARGARGARGARAAYGAYYTNTTYAARGGN GGNAGYTCNGARATHAARYTNGARTCNGAYGARGAR------------------------ ------GGNGARGARCAYATHACNGARCCNGCNGAYGCNGCNGCNTCNGCNGCNCCNACN ---------GTNGCNCCNGTNAARGARGTNACNCCNGARATHTCNGTNTCNGARGCNATH ACNGCNAARACNAARATHGCNGCNCCNTCNYTNAARGAYGAYTTYTCN------GARGAY AAYGARGARAARGARYTNTAYGAYYTNGAYATHAARATHACNGAYAAYGTNAARATGGGN GAYGGNATGTCNGCNTAYATGGTNTTYAARGTNGTNTCNAARACNACNAAYCCNGCNTTY MGNCAYCCNGARAAYACNGTNYTNMGNMGNTTYAGYGAYTTYYTNGGNYTNCAYGCNAAR YTNGCNGARAARCAYGTNCCNYTNGGNATHATHGTNCCNCCNGCNCCNGARAARAGYGTN ATHGGNATGACNAARGTNAARATGTCNAARGARGAYTCNGGNAAYATHGAYTTYATHGAY MGNMGNAARGCNGCNYTNGARMGNTAYYTNATHMGNACNTCNTGYCAYCCNGTNYTNGCN GCNGAYCCNGAYTTYATHGARTTYYTNGARAARGAYGGNGAYYTNCCNAARGCNACNAAY ACNTCNGCNYTNAGYGGNGCNGGNYTNATGMGNATGTTYCAYAARGTNGGNGARTCNYTN GARAARATHTCNYTNAARGTNGAYGARAGYGAYGARTGGTTYGARGAYAARCAYCARCAR ATHGARGCNYTNGAYATHCARYTNMGNAARYTNCAYACNAGYYTNGARACNYTNGCNACN CAYMGNMGNGAYYTNTCNGGNAAYACNGCNATHTTYGCNAARAGYGCNGCNATGYTNGGN AAYGTNGARGARCAYACNGCNYTNTCNMGNGCNYTNTCNCARYTNGCNGARACNGARGAR AARATHGARATHGTNCAYAARGAYCARGCNGARGTNGAYTTYTAYATHATGTCNGARYTN ATGAARGAYTAYGTNATGYTNATHGGNGCNGTNAARGAYGTNTTYCAYGARMGNGTNAAR ACNTAYAARCARTGGAARGAYGCNGARACNAAYYTNACNAARAARMGNGARATHAARGCN AARYTNGARATGCARGGNAARGCNGAYAARYTNGCNCARGCNMGNGCNGARATHACNGAR TGGGARCARAARGTNGARAARGGNCARGARGAYTTYCARAARATHTCNAARAAYATHMGN AARGARGTNGTNMGNTTYGARAARYTNMGNGTNGCNGAYTTYAARAARAAYGTNATHAAR TAYYTNGARGTNYTNATGGARAAYCARGARAARYTNATHAARTAYTGGGARACNTTYYTN CCNGARGCNAARGCNATHGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AAYGARGAYGGNGAYMGNCARGGNYTNGCNCCNACN GARGGNCCNMGNGAYGAYYTNATHAAYACNGCNGTNAARTTYYTNYTNAAYCCNAARGTN ATGGGNAGYCCNYTNCAYCARAARAARGCNTTYYTNACNAARAARGGNYTNACNCARGAR GARATHAAYYTNGCNGTNCARMGNGCNGGNGTNACNGAR--------------------- ---YTNGCNGCNCCNAGYCCNAGYCCNGAYTAYCARCCNGGNGTNYTNACNCCNCCNGTN CCNGGNGCNTAYGGNCCN---------CCNATHCCNCCNCARTCNMGNTGGGCNCARATG MGNGAYYTNTCNGTNACNACNGTNGTNGTNGTNGGNGCNTCNTAYGCNATGTAYCARYTN TAYAARACNTAYATHGARCCNYTNATHMGNGGNAARTCNGCNCAYGARCARMGNYTNGAR MGNYTNGARACNGARGTNGARGCNATHCAYAARTCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GTNGCNACNAAR ATHGCNMGNTGGTGGMGNGARCARMGNGCNGGNTTYATHGARCARAGYATHCCNAARTGY TGYCCNAARTCNATGGTNTAYCAYATHTCNMGNYTNCCNGARTGYMGNAAYTTYYTNMGN AARGARAARCARMGNATHYTNCARCARATHGARAARGARGAYGGN---MGNGCNGAYYTN TTYGCNACNYTNGCNGGNYTNGARGAYTTYACNAAYCARGTNTCNTCNGCNTTYTTYCAY ATHAGYCARGCNGTNMGNYTNATHCCNACNTGYGCNGAYTAYYTNTGGATGAARGARAAR YTNCAYMGNCARTGYCARGTNYTNGARAARCARGCNGARGCNAARAARCARYTNGTNGAR MGNACNTTYGGNTTYCCNTCNTTYACNGARGTNCCNMGNATHTCNTGYGAYGGNYTNAGY GTNGCNGARTTYCARGARAARTAYATHAARGCNGGNAARCCNGTNATHATHACNGAYGTN GTNGAYGGNATGACNGARTCNACNTTYGAYTAYACNYTNGTNTCNAARTAYGCNGGNAAY ACNACNATHACNTCNMGNGARGCNGTNTGGGAYTCNYTNTCNTGGGCNAARYTNGARGAY AARMGNGARGTNACNGTNGCNGAYYTNATHMGNGAYATHCARACNGAYTCNGCNAARGAY GTNYTNTTYGAYTGGAGYYTNCCNYTNCAYTGYCCNMGNYTNGCNGARGARATHACNATG CCNTCNTTYTTYCARAAYAAYYTNYTNYTNMGNACNAGYCCNGGNTCNYTNTAYGCNGAY AGYTGGCCNAGYYTNTTYATHTCNCCNAARGGNGCNATHACNAAYYTNCAYGTNGAYGCN TTYCAYTCNCAYTTYTGGATGGCNYTNTTYCARGGNCARAARMGNTGGACNTTYTTYGAY CARCARGAYGTNGCNTAYYTNTAYCCNCARTGGGTNCAYTCNATGGAYCCNGTNTTYAAR ATHGAYATGCARCARCCNGAYYTNGAYMGNTTYCCNYTNYTNGCNYTNACNMGNCCNCAR MGNTGYGTNYTNCARCCNGGNGARYTNYTNTTYGTNCCNGCNGGNAGYCCNCAYTTYGTN GARAAYYTNACNTCNAGYYTNGCNATHTCNTCNAAYTAYGTNGAYAGYACNAAYTTYCAY CARGTNTGYAARGARYTNGARATHAAYGCNYTNCARGAYGAYMGNGCNAARGAYYTNYTN CARCARYTNCARGAYCCNGAYTTYATHTCNMGN---------------------GTNATG GARTTYYTNACNGCNGARGGNTGYTGYTCNGCNAAYATHCAYCARMGNATGAARTTYGTN CAYGGNGAYATGTGYATHACNAAYGGNGCNGTNCCNAARTGGATHMGNATHTTYNNNGAR ATGTCN------------------------CARTCNCARMGNCARAAYTGYYTNATHGCN AGYGAYGTNGGNCAYCAYMGNATHCARMGNACNATHMGNGCNAAYGTNMGNGGNGTNAAR CARAARGAYGCNGCNGAYGARGTNGGNATHTCNAARGARCARGARCAYCAYGTNATGACN TCNYTNYTNGGNTAYMGNAARGTNTCNGTNMGNTGGGTNCCNMGNCARYTNACNTCNGAR ATGAAYGTNCARACNAARCARAARATHATGACNTCNTGGGTNGAYYTNGARACNAARMGN CARTCNTCNTAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ACNGGNACNCCN GARGARTCNCCNMGNAARCARGTNMGNGARGARAAYTAYGARGAYGARGCNGARGAYGGN GTNTAYGARAAYGARCCNGTNCAYMGNGAYGAYGTNGCNMGNGARACNGAYCAY------ ATHGARGCNYTNCCNTCNCCNGGNYTNGCNCARAAYYTNYTNGCNAARTTYAARTCNGGN GARGTNCARTCNTCNACNCCNMGNGCNAARMGNGARATHACNCCNCCNAAYCCNACNATG GGNGGNGGNGARTAYGTNTCNGARCCNMGNGCNGTNYTNGARCAYTAYGARGGNAARGCN GARTCNGGNGTNTTYGARAGYGARCCNCARCAYAAYCCNGAYGTNATHMGNTCNGGNATH AAYCARCARGARGTNGTNCCNGARCAYGGNTCNGCNAARAARTTYGCNGCNMGNTAYCAR CARATHGARAGYGARAARACNACNCCNGTNYTNTCNAAYMGNMGNGARATHACNCCNGAY MGN---ACNGCNCCNGTNGARTAYGTNTCNGARCCNCARGGNTAYGTNGARAARTAYGAR GGNAARGCNGARTCNGGNGTNTTYGARAGYCARCCNGARGTNATHCCNGAYGTNGTNMGN GCNGCNGAYGGNGTNCCNGCNGTNGTNGTNCCNGARMGNGGNACNGCNAARAAYYTNGCN GARMGNTTYMGNCARATHTCNGARGAYGCNGCNCCNGTNGCNAGYAGYMGNAAYAARMGN GARATHACNGCNGARAGYAAY--------------------------------------- ---------------ACNACNGARTCNGGNGTNTTYGARAAYACNCCNCARGARGAYCCN GARGTNGTNAARGCNGCNAGYGCNACNGARGARTAYGTNCCNGARMGNGGNTAYGCNAAR AAYGTNGCNGCNAARTTYAARGARYTNGARAGYAGYGCNAARTCNCCNCCNYTNTCNCCN GGNMGNMGNAARGARTTYACNCCNCCNMGNGARGAY------AGYMGNGTNGCNGGNGTN TAYGARAGYACNCCNGARTCNAARCCNGAYGTNATHACNTCNGGNGAYGCNAARCARGAR GTNTTYGCNGGNGCNGGNACNGCNMGNTCNYTNGCNCARMGNTAYAARGARATHGARGCN CARAAYAARTCNCCNGTNACNTCNAARCCNAARAARGARTTYACNCCNCCNCCNACNGAR TCNTCNGTNGTNGARAAYAARCCNGARMGNTTYCARGCNGAYTAYAAYMGNCCNGCNGAR TCNGGNGTNGTNGARAAYGARCCN---GTNCARMGNGAYGAYGTNACNAARTCNGGNAAY GARCAYGCNCCNGGNCARGAYYTNCCNGARGCNGGNTCNGCNAARAAYYTNGTNAGYMGN TGGMGNCARATHGARTCNGAYAGYGCNAAYGCNTCNTCNCCNGGNTCN------MGNCAY AARGARTTYACNCCNCCNMGNGAYGARCCNMGNGTNGCNGARAGYAGYAARTCNCCNMGN ACNCCNAARTCNCCNAAYGGNCARYTNGAYAAYGGNTCNGTNCAYCCNTCNGARYTNCCN GGNCARTAYCARCCNCARGAYGCNCCNAGYGTNTTYGARTCNACNCCNGARACNAAYCCN GAYGCNACNMGNGARACNGAYACNGAYTGGTCNCARGGNATGCCNAARAARAAYCARGCN AARAARYTNYTNGCNAARTTYCARAAYATHCARGCNGARGCNAAYAARGARCCNCCNAAR CCNGTNACNMGNAARAGYAARGTNGAYCARGTNTAYMGNAGYYTNYTNYTNACNAARTTY TTYACNAARGGNTGGGGNAARCCNGAYAAYYTNAARMGNATHTTYGARTTYMGNAARATH YTNTCNAAYMGNGARTCNTGYCARAGYYTNGTNTCNAARGAYTAYCCNATHACNATHGAY AARGAYTAYAARGAYGGNGAYATHMGNATHYTNGARGGNCAYTTYAARTCNCCNTTYGTN GAYCARATGCCNGGNATHATGCCNAARGARGTNGARACNGCNAGYTTYCARGCNGTNYTN CCNGTNGARTGGCARAGYCARGTNATGAARCCNATHTGYATHCAYYTNGCNGGNACNGGN GAYCAYTTYTTYTGGMGNMGNMGNYTNTTYACNGCNMGNCCNYTNYTNAARGAYGCNGGN ATHGCNTCNATHYTNYTNGARAAYCCNTTYTAYGGNTCNMGNAARCCNAARTCNCARACN MGNTCNAGYYTNCAYAAYGTNAGYGAYYTNTTYGTNATGGGNGGNGCNYTNGTNYTNGAR TCNYTNGCNYTNYTNCAYTGGTGYGARMGNCARGGNTGGGGNCCNYTNGGNYTNTCNGGN GTNTCNATGGGNGGNCAYAAYGCNTCNGCNGTNGCNACNGTNTGGCCNAARCCNATHTCN YTNATHCCNTTYYTNTCNTGGACNACNGCNTCNACNTCNYTNACNAARGGNGTNATGAGY GGNGCNATHCCNTGGCARGTNYTNCARGARCARTTYTTYAARAAYAAYYTNTAYCAYGAY GARATHAGYAARYTNATHGTNTCNCCNGARAARGCNTAYCARYTNGGNCARCARTTYGTN ATHAAYTTY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AGY TTYMGNGARGGNTCNTCNTGYAARTAYAGYCAYMGNTGYTGYATGCARAAYTGYYTNGAR GGNTAYGARTTYTGYATHMGNCAYATHYTNGARGAYAARATHGCNCCNTTYMGNCARTGY GCNTAYATHACNAARGCNGGNMGNAARTGYCCNACNGCNGCNCCNAARCAYGARAARAAR GARGGNTAYTGYTCNTTYCAYACNAARAARGCNYTNATGGCNMGNCARMGNYTNGCNMGN AARMGNMGNCCNMGNGARACNCCNGAYAGYYTNYTNGARGARYTNGTNGTNACNACNTCN TTYATGGAYGCNTCNCAYGGNATGGARCAYMGNMGNGGNAARATHCAYAGYGAYAGYYTN GCNACNMGNGCNYTNGAYTAYGCNAGYTCNAGYGAYTCNGARGCNGARCARYTNGTNGTN GARCAYACNTGGAARGAYTCNGGNGAYAGYGAYGCNGARAGYATHGAYAGYGAYCARGAR GAYATGYTNAARTAYGCNGGNATHTAYACNACNGARGARGTNGCNCARATHYTNMGNGAY AARYTNATHMGNYTNCARGCNYTNTAYATHGAYCARTTYAARMGNYTNAARCAYATHYTN YTNACNAARMGNAARAARTAYYTNCARGCNAARAARGTNGARMGNGARYTNTAYGGNAGY ATHAARMGNTAYAARAARGAYCCNCAYCARMGNGARAARTAYGARAARYTNTGYGCNATG AARMGNTAYCAYAARAARTTYGGNGTNGARGCNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AAYYTNCARAARGARATGGARAARYTNAARGAR GCNYTNTCNTCNTGYGAYTAYMGNATHAARTGGTTYCARAAYAARYTNAARGAYGARYTN GARACNCAYAARGARACNAARTCNAAYYTNGARAARACNACNTCNAARYTNAARGARGCN MGNGARGARACNGARATHATHMGNMGNGARTGYCARGCNATHGTNAARACNTAYCARGAR TCNGARGARATHAARTCNAAYAGYYTNGAYAARGARYTNAARATHAARGAYTCNCARYTN AARYTNMGNATGCARGARTGGAAYGAYACNGARGARCARCAYCARMGNACNAARAARGAR YTNGARTCNYTNAARGTNYTNCAYAARGARGTNGTNGGNCARGCNGCNACNYTNAARGAR AARGTNCARAAYYTNGARATGGCNGTNGCNGARAARGAYACNGGNATHTCNCARTCNAAY GARYTNYTNAAYAARCARAARACNGAYYTNACNGAYYTNACNTCNAARYTNAARGARMGN GARAAYATHAAYGARGAYTTYACNMGNGCNCARGARATGATHAARACNYTNGAYMGNGAY ATHTCNGARYTNAARATHACNAAYMGNGAYYTNCARAARGAYATGGAYTCNTGYMGNGAR MGNGARTCNAARATGYTNGCNYTNCARTCNGARYTNAGYAARACNAAYGCNYTNYTNMGN TCNGARAAYACNGCNYTNAGYAAYAARGCNACNAAYYTNACNGCNGARGTNGARMGNYTN AARATGGARATHCARGARYTNGARACNACNGTNMGNCAYYTNACNGAYTCNYTNGARGAY GARAARAARAAYAGYACNGTNACNGTNGCNAARYTNCARGCNTCNGTNGARGARAARACN AARGARAGYTCNGAYTTYAARCARAARTGGGARGAYGARATHGAYAGYAAYAARACNYTN AARMGNMGNCAYGCNAAYAAYGTNAARGAYYTNACNMGNCARYTNCAYCARACNAARMGN MGNYTNGARTCNYTNGARGGN------AGYGGNAGYGGNGGNAGYATGGGNTCNMGNACN AAYTCNAAYGGNAGYYTNAAYTCNATGGAYAAYAGYAAYTCNCARTCNGGNGCNACNACN GCNTCNGCNCCNGCNCARGARTTYCCNGTNATHACNGARCARGTNGARATHGAYAARCAR GTNYTNATHGARMGNATHGTNMGNYTNCARAARTCNCAYGCNMGNAARAAYGARAARYTN GARTTYYTNGGNGARCAYATHCARCARYTNYTNGARGARATHAARAARAARAAYNNNATH ATHCARAGYTAYGTNATGMGNGARGARGCNGGNACNYTNTCNTCNGARGAYATG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARGCNAAR ACNGAYGCNACNGARAGYTAYCARACNTTYGTNYTNCAYGAYGARGAYCAYACNYTNGGN AAYACNYTNAARTAYGTNYTNAAYAARAAYCCNGARGTNACNTTYGTNGGNTAYAGYATH ACNCAYCCNTCNGARAGYAARATHAAYYTNMGNATHCARACNACNGGNAARCCNGCNATG CARGTNYTNMGNCARGGNYTNAARGAYYTNAARGARYTNTGYGGNCAYATGYTNACNACN TTYGARTCNTCNACNAARTAYTAYAARGARAAYCAYYTNGARATG---TCNGAYATGGAY CARTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GTNTGYAARACNTGYTCNAGYAAR GAYYTNYTNYTNTAYGTNCCNGAYGGNAAYTCNAARTGYAARATGGCNATHATHAARATH ATHGGNTGYCCNGARGTNGARCCNGARACNAGYYTNYTNGTNMGNGTNTGYCCNGTNTGY MGNGARMGNYTNATHTCNCARCARGTNGAYTCNCARGARGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNYTNGCNATGTGGGAYYTNGARCAYTGYGAYCCNAARAAR TGYACNGGNAARAARYTNTGYMGNYTNGGNATHGTNAARACNYTNMGNYTNAAYCARMGN TTYAAYGGNYTNATHYTNTCNCCNATGGGNACNAARTGYGTNGCNCCNGAYGAYMGNGAR ATHGTNGARCARAAYGGNATGGCNGTNATHGAYTGYAGYTGGGCNAARYTNCARGARACN CCNTTYTCNMGNATGAARGGNGAYCARYTNMGNYTNYTNCCNTAYYTNATHGCNGCNAAY ACNATHAAYTAYGGNMGNCCNTGYAARYTNTCNTGYGTNGARGCNTTYGCNGCNACNYTN TAYATHACNGGNTTYACNAARGARTCNCAYATGGTNYTNGARAARTTYAARTGGGGNCCN TCNTTYTTYTCNYTNAAYAARGAYTTYYTNGAYAAYTAYTGYAGYTGYCAYACNAGYCAR GARGTNGTNTCNCARCARGAYAARGTNYTNGCNCARYTNCARGARGAYAARCARCARGAY AARYTNACNGAYTGGYTNTCNATGGAYCCNGAYGTNGAYGTNTGYAAYCCNAAYMGNCCN ------YTNTAYCCNCCNTCN---------GARACNAGYTCNGAYGAYGGNACNGARGAR GARAGYGAYGARGAYGARCARGAYGARGAR---------------------GARYTNGTN AGYMGNACNGCNATGAARTGYGCNACN------AARAAYCCNAGYTTYTTYGCNGARGTN GCNGARCAYTTYGCNAGYAARACNAARATHGAY---ATGAARTTYGTNTGYMGNTAYAAR CARGTNATHGTNACNACNYTNMGNTGYTTYYTNAAYAAYATHGARGARTGYGTNCCNGAR CARYTNAARTCN---YTNTTYAGYYTNGTNCCNTCNGAYGAYCAYATGATHAAYGGNYTN GAYTTYATGTGYAAYCAYACNAGYGTNYTNAAYAGYAAYTGYATGGAY---GAYCAYYTN CARTCNTTYATGGARTGYTAYMGNGAYMGNATHGGNGGNACNGARGCNATHGTNGCN--- ---------------------AAYCCNYTNGTNTGYAARATHGTNMGNTAYGARGARAAR TGYATHATGGARAAYMGNGCNTCNTGYACNGAYGARTTYYTNAARATHYTNTTYACNACN YTNGARAARTTYTTYCCNATGTCNCARTGYCCNAARAGYGCNGCNGCNYTNGARAARTTY AAYACNCCNYTNGGNGCNATHYTNMGNMGNGGN------------------CARCCNCAR GGNAAYGCNMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TAY GGNYTNTTYATGATGGARGARATHAARGTNTCNCCNAGYGGNTTYCAYYTNACNCARGGN CCNGGNAAYTAYAARATHCCNTCNTTYGGNAAYATHCCNGCNCARTTYAAYGTNTCNYTN GTNCCNGAYAGYMGNAAYCCNTTYGCNGTNTTYTCNTCNAARGGNATHGGNGARCCNCCN YTNYTNYTNGCNGGNGARTCNCCNGCNTCNGTNTCNGARAARYTNCAYACNYTNYTNAAR TCNYTNCCNAAYTTYGGNCCNCCNYTNCCNMGNMGNGGNAGYYTNGTNMGNACNGGNTCN YTNMGNATHCAYMGNAGYTCNTCNYTNGAYYTNAAYCCNAAYCARTCNGCNACNTCNTCN MGNYTNTCNTGYGCNGARGAYTTYCCNMGNCCNAGYGAYMGNGCNGAYTCNGTNCCNTCN GCNGTNMGNGGNTGGCAYCARGCNGGNGARGGNATHYTNCARACNCCNTCNCCNAGYGAY AGYGGNGTNGGNGARYTNGARGCNATHYTNMGNGARAARGAYGCNGARATHAAYACNYTN MGNGARGTNATGGAYMGNAAYGARMGNGCNATHYTNCARGTNTAYGARGARMGNAARAAY GCNTGGGCNYTNGAYACNCARGAYYTNAARGARGARTAYGARMGNAARYTNAARATHCAR AGYMGNAARTCNTAYAARACNGARCARGTNYTNTCNYTNCARGTNTAYAARYTNCARCAR GAYCARAARGCNYTNYTNGARGARAARGARACNYTNGTNGGNGARMGNGAYAAYYTNAAR ACNCARYTNGARGGNACNAAYACNGARATHTCNAGYYTNAAR------TGYAARYTNGGN GTNACNTCNGGNGCNGAYGGN------AGYGAYTCNCCNAAYTCNAAYGARGARYTNGCN YTNAARAAYAARGARGTNATHAAYYTNCAYACNCARATHCAYACNTTYCARGTNGAYATG GARAARAARAAYAARGARYTNGGNGARAARGCNAARGARYTNATHGGNTGYAARGARGAR GTNGARAARGTNAARAARGARYTNGARMGNYTNAARAAYCCNCCNGTNYTNTGYGARCAR TCNAGYCARACNCAYGCNCAYTGYGARGTNTCNAGYYTNGARAAYGTNAARCCNTCNATG ATGGGNGARMGNGARMGNACNATHCARACNYTNCARGTNGARYTNGAYGARYTNMGNAGY CARGTNYTNGARATGGAYGAYMGNCAYGARAARGARAARGAYCARTGGYTNGARGARAAR AAYAARGTNATHMGNTAYCARAARCARYTNCARYTNAAYTAYGTNCARATGCARMGNAAR AAYTCNACNYTNGARACNGARGTNCARCARYTNACNYTNGARYTNGARAAYMGNGAYATG AARYTNATHGCNYTNAGYGGNGARGARAGYGTNTGY------------------------ ACNGCNGTNGTNYTNCAYATGGGNTGYYTNGTNTAYATGTGYYTNTGGCARCCNTCNYTN GAYTCNYTNYTNCCNTAYTTYGTNGTNATGGGNGTNTGGGGNATHGGNGAYGGNTTYTGG AAYACNCARATHAGYAGYYTNATGGGNGTNATHTTYCCNGCNAARTAYGARGARGCNTAY GCNGGNYTNMGNATHACNCARGGNYTNAGYGTNGCNATHGCNTTYGGNTAYTCNAGYGCN YTNTGYATGACNYTNAARATHTAYATHACNATGGCNGTNTGYGTNYTNGGNYTNGTNGGN TAYYTNGTNATGGARGCNAARCAYAARMGNGAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNGCNAGYTAYATGAARGGNTCNATHGGNGTNGGNCARYTN AARGTNAAYTAYCCNCARYTNGAYTTYACNCCNAGYGCNYTNTTYGCNATGGGNTCNCCN ATHGCNYTNTAYYTNTCNYTNMGNGGNATHGAYGARGTNGGNGARTTYTTYCARYTNCCN ACNTGYCCNMGNGTNTTYAAYATHTTYCAYCCNTTYGAYCCNYTNGCNTTYMGNYTNGAR CCNYTNATHMGNTCNAAYATGGCNCARACNAARCCNGTNCARGTNCCNCAYTAYAARGGN MGNAARMGNYTNCAYYTNGARTTYAARGARGCNGTNACNMGNTAYGGNACNGAYATHAAR CARAARATHGTNGARTCNYTNAARAGYGGNTGGAAYAGYYTNAAYGAYTTYGCNAARGCN CAYATHGARGGNAGYAARGGNATGGARACNGCNGTNCARTCNGARGTNGAYCARATGATG AARCAYATHTCNCARCARCAYGCNGARGAYGAYGTNGCNTCNGTNTCNTCNATGGCNGAR GARGARATHCAYATHGGNCARYTNAAYGARGGNCARMGNGTNGAYTAYCARYTNCARGAR GGNCCNYTNGARAGYTTYAAYGAYTAYYTNTTYGCNYTNACNTCNCAYTCNTGYTAYTGG GAYTCNGARGAYACNGCNYTNYTNATHYTNAARGARATHTAYATGCCNCAYCCNTCNMGN TTYCCNCCNCCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GGN MGNAAYAARAAYMGNCCNMGNAAYGARMGNGTNTGYGARAARGAYAARYTNTGYCCNTCN ATHAARCARGARAARGARTGYMGNTTYGGNGAYAAYTGYAARTTYAAYCAYGAYGTNAAR TCNTTYYTNGARAAYAARMGNCCNGAYATHGARGGNTCNTGYCCNGTNTAYGARACNTGG GGNTTYTGYMGNTCNGGNGTNAGYTGYMGNTTYGCNAGYTGYCAYYTNGGNGARAAYTCN GARAAYYTNGTNAAYAARGARYTNTTYGARACNATGAARGAYAARCCNCARTCNYTNAAY AGYYTNAARGARGAYGTNMGNCARAARYTNTGGAARAARAARTAYGAYTTYGGNAARTCN ATGACNTCNGTNAAYAAYGTNCARCAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNATGAAYAARAARACNGAYAAYGGNGARAGYYTNCARYTNGAYTGY AAY------------------------------------------------GAYGGNAAR GARMGNATHGARGCNGTNGCNAAYATHGARGAYGTNCCNATHMGNTCNMGNGARGTNAAR AARATHGAYTTYCAYAAYAARYTNTAYYTNGCNCCNYTNACNACNGTNGGNAAYYTNCCN TTYMGNMGNGTNTGYAARAAYAAYGGNGCNGAYATHACNTGYGGNGARATGGCNYTNGCN TCNCARATHYTNAARGCNAARGCNTCNGARTGGTCNYTNATHAARMGNCAYCCNAGYGAR GAYATHTTYGGNGTNCARGTNTGYGGNGCNTTYCCNGAYYTNATGACNAARTGYGCNCAR GTNATHGCNGAYACNACNGAYGTNGAYTTYATHGAYATHAAYTGYGGNTGYCCNATHGAY YTNGTNTTYAARAARGGNTCNGGNAGYGCNYTNATGGGNMGNGTNTCNAARYTNGARCAR ATHTGYMGNAGYATGATGGGNGTNATGGGNGARATGCCNYTNACNGTNAARYTNMGNACN GGNGTNTTYGAYAAYAARAAYGTNGCNCAYAAYATHATHCCNMGNYTNMGNGAYGCNGGN GTNTCNYTNGTNACNATHCAYGGNMGNTCNMGNGARCARMGNTAYACNMGNGTNGCNGAY TGGGAYTAYATHGAYGARTGYGCNMGNYTNGGNAAYCCNATGCCNGTNTTYGGNAAYGGN GAYATHYTNTCNTAYGARGAYGCNAAYYTNCAYATHAAYAARAAYGGNGTNTCNGGNGTN ATGATHGCNMGNGGNGCNYTNATHAARCCNTGGATHTTYACNGARATHAARGARCARMGN CAYTGGGAYATHTCNTCNGGNGARMGNTTYGAYATGYTNAARTCNTAYACNAAYTAYGGN YTNGARCAYTGGGGNTCNGAYCAYCARGGNGTNGARACNACNMGNMGNTTYYTNYTNGAR TGGCARTCNTTYYTNCAYMGNTAYATHCCNGTNGGNYTNYTNGARCARYTNCCNCARAAR ATHAAYGARAARCCNCCNTAYTAYGTNGGNMGNAAYGAYYTNGARACNYTNATGGCNAGY CCNAGYTGYGCNGAYTGGATHAARATHAGYGARATGYTNYTNGGNCCNGTNCCNTCNAAY TTYCARTTYYTNCCNAARCAYAARGCNAAYGCNTAYCARATGAGYTCNCAYAGYCARCAY ACNGARTGGATHYTNGARACNATHGAYCAYYTNMGNAARMGNAARGCNMGNCCNGAYYTN CAYMGNATHTGYCAYGTNGTNMGNMGNMGNTTYGGNYTNCCNAGYGARGTNACNGARGTN AARYTNGARAARYTNGTNGAYGCNGARATHGTNATHAARGTNGARTAYAARGGNAGYACN AGYTAYMGNAAYGCNTCNAARTGGMGNAARAGYATGATHGGNTGYGCNGTNCARAAYTCN ACNATGATGTCNACNAARATHATHGARGCNATHATHGCNYTNTCNAARACNAAYGTNAAR GTNAAYAGYAARTCNAAYGARAARGAYTCNMGNGARAAYGCNACNGAYCCNAARAGYTCN AGYYTNAGYTTYCCNAARAARGCNGARGARGTNGGNGTNTCNTCNGAYGAYATHGARAGY TGGYTNTCNGCNAAYTGYGAYGCNTTYGCNAAYYTNAARAGYCCNYTNAAYGTNGTNYTN AARMGNGARATHGAYGCNGGNMGNATHCARAARGTNGARAGYGGNAARTTYGTNYTNTCN AARGCNCARAARGARGARYTNAARAAYGAYACNGTNAARYTNGTNACNTCNAARAARCCN GAYTCNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARATHYTNMGNACNGAYTCNTCNGAYAAYATGTAYGTN CAYAAYTGYACNGARGTNGARGTNAARCARCCNCARGAYGCNATHGAYGTNTTYTAYAAR GGNCARMGNMGNMGNAARGTNGCNCAYACNACNYTNAAYGCNGARTCNAGYMGNAGYCAY AGYGTNTTYAAYATHMGNYTNGTNCARGCNCCNYTNGAYGCNMGNGGNGAR--------- ---------------------------------TCNAGYTCNGCNGAYATHYTNGARTTY CARMGNAARATHCARGARYTNGAYGCNGCNYTNGCNAARAARGGNGARGARYTNCARCAR CARGCNACNTCNYTNCAYGARCAYCAYMGNACNAARATGGCNACNYTNAARGAYMGNCAY GCNAARGARGTNCARACNYTNCARGAYAARYTNGCNGCNCARGGNCARCARYTNACNGGN TCNCARCAYMGNGGNACNYTNCCNGARTCNGARMGNCCNAAYGCNCARAGYMGNATHGGN GARYTNGARMGNAARYTNGCNACNGCNYTNAGYGARAARGARAARGTNCARAAYGCNMGN ATHCAYYTNGARGGNATGYTNGARGARYTNCARCARGARGTNGARMGNYTNCARMGNCAR GARCAYGCNGCNCAYAGYGAYGGNAAYGTNACNGCNYTNCARTCNCARGTNTCNAARYTN TCNCARTGYYTNACNGARACNMGNAARGARAAYGARAGYYTNMGNCARMGNYTNAARGCN AARAAYGARGTNTCNGTNGCNYTNYTNGCNGCNAARGARGARMGNGAYGCNGTNATGATH AARATGGARGARATGATGTCNACNATHGGNGAYGARGARAGYCARATHAARACNTCNGAR YTNYTNAAYACNATGGARAARGARAAYACNGTNYTNAARGARCARAAYGTNAARYTNGAR GARCARGTNYTNATHCARGARMGNGTNYTNTCNAAYCAYATGACNGARAARMGNTCNYTN YTNGARACNYTNGCNACNYTNCAYTCNCCNGGNGCNAARGAYGARAGYATHTCNGARTCN GAYACNTAYTGYTCNACNAGYYTNTCNTCNGAYGCNYTNCARYTNAAYGAYGARGARATH GAYGCNGARGTNAARCARYTNMGNTCNAARYTNGARAARATGATGGAYGAYTCNTCNAGY TTYGAYYTNGARMGNTCNGAYTGGCARATGGARAARGARGCNYTNGARGAYATHGTNACN GAYYTNMGNAARAARTCNCARGAYCARGARGARGARATHGTNTCNYTNAARAGYTCNGAR ACNCCNACNTCNGCNYTNTCNYTNGAYCARCAYGARGGNCARYTNGARAGYTGYAGYCAR YTNGARAGYCARGTNACNTCNYTNMGNGARGARAAYCARGARYTNGARAARGCNYTNGAR GARYTNGAYTCNCARCAYTCNGAYGCNGTNGCNCARYTNATHMGNCARMGNGAYAARATG GCNGCN---------------------CARYTNYTNGARCARGARAARGARATHGAYGTN TAYMGNGCNGAYGCNAAYTCNYTNAAY------AARGARACNGTNACNCARYTNGARGAR AARTGYCARCARTAYCARACNGARYTNTCNGCNYTNAARGAYGARMGNCARGGNGARTCN GTNGAYAGYMGNGTNAARGARYTNAARGARAARYTNGARAARGGNGGNYTNGTNATHAAY GAYYTNCAYATGGAYAARCARGAYYTNGARCAYAARYTNCARAARGCNAARGARGARATH GARGGNAARGTNYTNAARYTNAARGARAGYMGNGARGAYAARGCNGCNYTNGARAARGAR ATGATGAARATGGARGARAARYTNCAYGARGTNGARGARMGNYTNATGGARTCNGARGTN GARYTNGARAARTGGCARCARYTNAARGARGAYMGNCARACNGGNTCNACNGARATHCAR GAYGTNGARATGGARTGYTCNMGNYTNMGNYTNAARATHGARAARATGGARCARGARMGN AARGCNTTYAARGARGAYTTYCARTGYYTNATHGAYGGNAAYAARGAYCAYGAYGAYYTN YTNTCNTCNGTNAARGAYACNGCNTTYCAYCAYATHTTYGARGARGARYTNAARGTNMGN CARAARYTNGARGARGAYGARAAYGTNGTNCARGARYTNMGNGARTAYATHGARAARYTN GGNGGNGARMGNCARACNYTNAARGAYACNGTNACNTCNYTNACNTCNCAYAARAAYGAR TCNGARTCNGTNYTNATGGCNGTNACNAARGARMGNGAYTCNTAYAARGCNCARATGGAR GARAARGTNGCNGARGTNAARGAYAARGARTCNGARGTN--------------------- ------------YTNAAYYTNMGNAAYGARYTNGARCARATGCARMGNATGAARGTNGGN YTNGARGARAGYYTNACNACNYTNMGNCARGARAARYTNGAYYTNGCNAAYYTNTAYGAY ATHMGNGARGARGARYTNAARGCNGCNGGNGARAARACNCAYGAYATGAAYGTNGARYTN GAYMGNYTNMGN------------------------ATHAARGAYGTNGARGARYTNMGN MGNTCNATG------------GGNGARAARAAYGARACNGTNAARAARYTNACNTCNGAY TGYGARATGTAYCARAAYCARATHAARACNATHAARACNGARATHGTNMGNYTNGARTGY YTNTGYGARGARAARGARGARGARYTNAGYAGYGTNAARGARMGNATGAGYCARTTYGAY MGNGAYYTNCAYGARATGGARGARTCNGTNAGYGTNACNMGNCAYCARAAYCARYTNATG ATGGARAGYAARGAYAARGARYTNMGNGAYYTNGARTCNGARAARAARAGYYTNGARACN MGNGTNATHCARCARCARGARCARGTNCARTCNTCNATGGCNGAYCARCARCARATGTCN GCNGAYYTNTCNAARATGGCNGCNYTNAARGARAARGARATHGTNMGNYTNCARACNCAR YTNCARCARYTNGARTCNGARYTNGCNTTYTCNMGNGARAARATHGCNAGYYTNAARGAY GARYTNTCNCARGTNMGNGARYTNATGGAYTCNCARAARGCNGGNATHGGNAAYGARAAY MGNAAYTCNGARGARGARAARATHGTNGTNGAYGTNATGCARAARGCNGARAGYGCNTCN CARAAYYTNYTNACNCARCCNATGAAYACNAAYGAYAAYAAYGAYYTNACNGARAARAAY GTNGCNAGYAGYYTNCAYATG--------------------------------------- ------------TCNAAYTCNCARTCNAGYAGYCAYGARGCNGAYGAYGTN--------- ------------------------------------------------------GAYMGN CAYMGN------------------------------------------------------ GARCAYTTYGARGCNYTNGARAARGARATGGARGARYTNMGNGARAARYTNAGYCARAAR GAYGGNGTNGTNYTNGARYTNCARMGNTCNAAYACNTCNYTNTTYGARYTNYTNGAR--- ---------AARAARGCNGAYAGYAAYAAYACNATHGCNACNCAYAARYTNGARYTNGAR YTNAARAGYATHMGNGCNGARMGNGARCARATGGTNGCNGTNGTNAGYGARAARTCNMGN GARAAYTCNTCNYTNAARGCNGARATHCAYMGNYTNATGGAYGTNGTNTCNGCNGGNCAR ACNGCNYTNAGYAARGTNCARCARGAYAAYGTNAARYTNGARCARMGNCARAGYTCNCCN CCNMGNGGNGAY------GARGARGAYGARATGAARMGNGARGCNYTNAAYAAYATGGCN MGNYTNGTNMGNGAYAARGAYACNGARATHGARGCNYTNACNCARAARAAYGAYACNYTN YTNGCNGTNYTNCARGAR---TCNAGYGARTCNGGNGCNGCNTCNCAYYTNGGNCCNYTN YTNAARGARAARGARGCNYTNAGYCARCARGTNGCNACNATHYTNTCNGARMGNGARCAR YTNATHGCNTGYGTNACNCARAARCAYTCNGARTCNYTNGCNTTYCAYGGNGARGTNCAR MGNYTNACNGCNGTNYTNATHGARACNCARGARGCNGCNGAYAARTCNMGNGTNGARTAY TCNGCNYTNATHCCNGCNTTYGARMGNAARACNCARGCNYTNYTNAGYACNCARCARGAR YTNGTNGARTGYAARCARAARYTNACNGARYTNGARATHMGNCAYGGNGARYTNATHCAR AARGCNAAYAGYYTNCARGTNGGNGAYYTNGARGCN------------GARGTN------ ------------------GARAARTAYAARMGNYTNGARTCNGAYTAYAARACNATGGTN GTNGARMGNGAYGGNCARATHCARAGYYTNTCNCARMGNATGAARTCNTTYGARGAYATG GCNTCNTCNAARGARGCNGARTGYGCNCAYYTNAARAARCARYTNGAYAAYTCNAARTTY CARYTNACNGGNYTNATGGCNGARATHGCNGARGCNAARTCNGARMGNGARYTNGTNCAR CARAARAGYGARTCNCARGGNGARGARTCNACNAGYYTNMGNAAYAGYATGAAYCARATG MGNYTNGCNGTNAARGAYAARGARCARGARATHGTNTCNYTNAARGARCARATHTCNACN YTNAAYACNYTNYTNCARAGYCARAARGGNGAYCARGAYCARGTNGCNYTNYTNATGMGN GARCAYGARGCNGCNGCNACNACNACNMGNCARYTNCARCARGARMGNGAYTAYAAYGCN ATGYTNGCNGAYCARMGNCARCARGARTGYGARACNTTYAARATHGARYTNTCNAAYCAR AARGAYAARGTNTTYAARATGACNMGNGARYTNGARMGNYTNMGNAGYCAYYTNATHGAR ATHGARGAYGGNTAYACNCARGARGCNYTNGARGCNGARGARMGNGARAARGARYTNMGN AAYAARYTNGCNATHGCNGARGARCARYTNTTYAGYTCNACNTCNCAYGTNCARYTNGCN AGYCARGARTCNCAYMGNCAYATHGARAGYYTNCARGARCARYTNCARCAYATHGCNGGN CARMGNGAYGCNGCNTAYATGCARGTNGCNTCNACNCARGAYCARTGYGARCARTAYGCN GCNTCNYTNAARAAYYTNCARYTNGTNYTNGARCAYTTYCARAARGARAARGAYTCNGCN ATHGCNYTNGARACNGARAARTAYCARGAYCARGCNAGYTCNYTNAGYGCNAARGTNAAR GAYYTNGARTCNGARYTNGARAAYACNMGNGGNGAYYTNACNGARGCNYTNGAYGGNYTN GARGCNGCNTCNMGNYTNAGYGARCARYTNGAYMGNAARCARGARGCNYTNGTNGCNYTN AARGARGARGTNYTNYTNMGNGARCARGCNYTNAAYGCNGCNGARGARGTNATHCARAAR YTNAAYTCNAGYAARGARGCNAARGTNGAYAARACNYTNATGCAYAAYATGGTNYTNACN TGGYTNACNTCNCCNGARAARAARMGNCAYGARATHGTNCARYTNATHGGNCAYGTNYTN GAYTTYAGYAARGAYGAYTTYTCNAARATHGARTCNGCNCAYAGYCARGAYAGYYTNTGG ATHGGNTTYTTYAARMGNCCNAARGCNGAYGCNGCNCCNCARCCNAGYCCN------GAY CARTCNTTYTCNCARYTNTTYGTNAARTTYYTNGARMGNGARTCNTCNCCNCCNCCNACN CCNGTNAARYTNCCNGTNGARTCNATGGCNGCNGARACNCARGCNMGNCAYAARACNAAY TTYAAYCCNTTYATGGCNCCNMGNCAYGTNACNCAYGGNAGYGARGCNTCNGCNYTNTCN TCNGGNGGNTCNTCNCAYYTNYTNATGCCNCAYGAYACNCCNCAYCCNTCNCCNYTNTTY GCNCCNGTNACN------AAYAGYGCNGGNGARAGYGCNATHYTNAARGAYGTNYTN--- ------------------------------------------------------------ ---------------TTYTCNTGYTGYAARGGNGAYTGGTGYAAYCARAAYYTNGCNCCN CCNCARCCNGCNATHGCNGARGARGARGGNCCNTTYAAYYTNACNTTYGTNYTNAGYATH ATGYTNTCNYTNGTNGTNGGNGTNYTN---------GTNGTNACNTTYYTNGCNATHYTN ATHTAYMGNMGNCAYYTNCAYAARAARMGNGGNYTNAGYTCNYTNATGGCNGARAAYMGN YTNYTNGARGAYGAYGGNTCNGCN---TCNATGTGYAARGAYCAR---TCNTCNGGNAGY GGNTCNGGNCARGCNAARYTNGTNTGYMGNACNGTNGGNAARGARGTNCAYYTNATHGAR AARATHGGNAAYGGNMGNTTYGGNGAYGTNTGGMGNGGNYTNTGGYTNGGNGAYGARGTN GCNGTNAARATHTTYACNTCNYTNGARGARACNAGYTGGMGNCARGARATGGARAAYTAY AAYACNGGNATGYTNAGYCAYGARAAYATHYTNGTNTTYCAYGCNTCNGAYACNATHGGN MGNTTYTCNTGYACNCARAAYYTNYTNATHGTNCARTAYCAYCCNAAYGGNTCNYTNTAY GAYTAYYTNCARACNAGYGAYATHGAYATGGARGARATGYTNGTNYTNGCNCAYTCNGCN GCNGCNGGNATHAGYCAYYTNCAYTAYGARATHAARCARGGNACNGGNACNCAYGARAAR CCNTCNATHGCNCAYMGNGAYATHAARTCNAARAAYATHYTNGTNAARTCNAGYGGNGAR TGYTGYATHGGNGAYYTNGGNCAYGCNATHAARAAYACNAARGARTGGGAYMGNGGNMGN GARAARYTNTGGGTNGGNACNAARMGNTAYATGGCNCCNGARYTNYTNGCNAARAGYYTN AAYCCNGCNCAYTTYGARTCNTTYMGNTGYGCNGAYGTNTAYGCNTTYGGNYTNGTNYTN TGGGARATHGCNMGNMGNGCNMGNCCNTTYTGYGARGARTAYMGNGTNCCNTTYTGGGAY YTNGTNCCNGGNGAYCCNAGYGTNGARGARATGAARAAYGTNGTNGTNGAYMGNGARATG MGNCCNGCNATHCCNAAYAAYTGGGCNCARGARCARYTNATGGTNGARATGGAYAARYTN ATGMGNGGNTGYTGGTCNCARYTNCCNTCNACNMGNYTNAAYATHYTNMGNGTNAARAAR AAYYTN---CARGCNYTNMGNTGYCARACNGARCARYTNATGGARAARMGNGARAARYTN TCNGGNAARATHYTNGAYGGNAGYACNACNACNAAYAGYGTNGTNACNACNTCNAGYAAY ATGYTNTTYAAYYTNGAYGAYTGGACNCARGGNATGGAYYTNYTNTGYGARGAYYTNAAY ---------YTNTTYAGYAGYCAYTTYGAYTGYYTNTCNAARTTYACNAAYMGNATHACN MGNTGYATHTGGATGMGNACNMGNATGTTYAARMGNGCNGTNATGGARGCNGGNATGGCN ACNCAYAARGCNYTNCAYGAYATHACNTGYAAYTTYGCNGARAAYATHGTNGAYTGYYTN GARCAYCCNYTNGCNAARGARTGYCCNATHYTNGTNGTNGAYACNATGGTNACNGCNYTN CAYMGNTTYYTNCCNCCNGCNTGYGCNCCNGTNCCNGCNGTN------------------ ------GAYGCNGGNACNAAYGCNGARCCNAAYGTNYTNGARACNGTNATHYTNGARGGN GGNGGNGGNATGGGNGAYTCNGGNATHGAYATGGAYATHTCNAGYATHATHGGNACNGAR GAYGAYYTNTCNGAYCAYCCNAAYAARTAYTAYGARYTNAARAGYACNGTNGTNGTNGGN AGYCCNGCNACNGARATHAARAAYGCNAGYGTNTCNACNMGNGCNAAYYTNAARCARCAR YTNCARMGNCARCARYTNTAYGAYCARGARAARMGNCARMGNACNATHAARAAYGGN--- CAYATHACNGGNTCNMGNGGNATHTCNGTNCCNCAYTCNGTNACNTCNTCNTCNGTNCCN TCNAAYGTNYTNCARGTNMGNACNCARYTNCARCAYCCNACNGARTAYCAYGTNMGNCAR AAYCARAARMGNCARGTNGARAAYTTYYTNCAYGARCARTCNGGNAGYCAYYTNCCNATH CARTCNYTNCCNACNTCNGTNGTNGAYCCNTCNYTNYTNCARCARCARCARCAYTAYATH CARACNTCNAGYAGYGCNCCNGARCCNGAYCAYACNAGYCCNYTNGTNTCN--------- ATGGGNGGNGARTTYYTNGGN---------GAYYTNYTNGGNGAYYTNTCNTCNGTNGAR CARYTNGAYYTNGGNAAYATHYTNAAYGAYAGYGAYYTNATHCCNATHCARCAYGGNGTN GGNCCNGAYTCNYTNAGYCARGGNGGNYTNGTNTCNGGNYTNGARGGNYTNGAYCCNGAY GGNGGNYTNTCNCARACNAAY---------TCNTGYCCNACNGGNCARTTYCAYGAYTCN GAYYTNGAYCAYACNGGNATHATGTCNGTNCARGAYGARYTNTGGMGNAARGARMGNATH AARAARGAYAAYCAYAAYATGATHGARMGNMGNMGNMGNTTYAAYATHAAYGAYMGNATH AARGARYTNGGNGGNYTNYTNCCNAARACNATGGAYCCNGAYTCNMGNCARAAYAARGGN TCNATHYTNAARGCNTCNGTNGAYTAYATHAARATGYTNCARGAYGARCARAARAARTAY MGNAGYYTNGTNGARGARAARAARAARACNGARATGGAYYTNMGNAARTCNYTNATHMGN YTNAAYCARATGAAYYTNGTNATGMGNTCNCAYGGNATHGARACNGCNGGNYTNGGNGAY YTNGARYTNACNTCNTCNGTNGCNGGNAAYCCNGTNAAYTTYYTNACNTCNCCNYTNACN ATGACNCCNACNACNCARGTNATGCARACNCARYTNATHTCNACNCARACNACNAAYGCN ATHTCNCCNGTNGAYGAYYTN---ATGGAYGARATGTCNCCNGTNAGYGGNGAYCCNATG YTNATGTCNGCNCCNGTNAGYCCNGAYYTNGAYGARGTNGGNTTYAAYTTY--------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGYTNCARGAYMGNATGGAYCAYYTNCARGAYGCNYTNAAYGCN TAYGGNCCNAAYTCNCARCAYTTYYTNAARGAYTCNGTNAGYAGYCCNTGGGARMGNGCN GTNGCNGTNAAYAARGTNCCNTAYTTYATHAAYCAYGAYACNGARACNACNCARTGGGAY CAYCCNCARYTNACNATHYTNATGGAYGCNYTNATHGAYYTNAAYAARATHMGNTTYGCN GCNTAYMGNACNGGNATGAARYTNMGNATGYTNCARAARAARYTNTGYATGGAYACNGTN TCNYTNCARATGGCNATGGARGCNTTYGAYACNCAYGGNYTNMGNGGNMGNAAYGAYAAR YTNATGGAYGTNGGNGARATHATHGARTGYYTNTCNTCNATGYTNGARGCNGCNGCNAGY CARCAYCCNGAYATHGTNAAYGTNCCNYTNAGYGTNGAYYTNACNYTNAAYTGGATHYTN GAYGTNTAYGAYAGYGTNMGNAGYGGNAARGTNMGNGTNYTNTCNTTYAARGTNGCNATG GTNYTNYTNTGYCARGCNCARYTNGARGAYAARTAYMGNTAYATHTTYMGNYTNATHGCN GAYACNAAYGCNTTYGCNGAYCARMGNAARATGGGNYTNYTNYTNCAYGAYTGYATGCAR ATHCCNMGNCARYTNGGNGARATHGCNTCNTTYGGNGGNAGYAAYATHGARCCNAGYGTN MGNAGYTGYTTYGARAARGCNAAYGGNMGNCCNGARATHGARGTNYTNCAYTTYYTNGAR TGGYTNAARYTNGARCCNCARTCNYTNGTNTGGYTNCCNGTNATGCAYMGNYTNGCNGCN TCNGARACNGCNAARCAYCARGCNAARTGYAAYGTNTGYAARGARTTYCCNATHGTNGGN TTYMGNTAYMGNTGYYTNAARTGYTTYAAYTTYGAYGTNTGYCARAAYTGYTTYTTYTCN GGNMGNACNGTNAARAGYCAYAARYTNACNCAYCCNATGCARGARTAYTGYACNACNACN ACNTCNGGNGARGAYGTNMGNGAYTTYTCNAARGTNTTYAARAAYAARTTYAARTCNAAR MGNCAYTTYAARAARCAYCCNMGNMGNGGNTAYYTNCCNGTNGAYTCNCAYYTNGARGGN GAYAGYYTNGARAGYCCNAAYCCNTCNCCNCARCAYAGYATHTCNCARGAYATGCAYTCN MGNYTNGARATGYTNACNAGYMGNATHGCNGARGTNGARCARMGNCARGGNAGYTCNGCN GAYTTY------------------------------------------GARGAYGARCAY CAYYTNATHGCNCARTAYTGYTCNAGYYTNAAYGGNGARCCNAAYTCNCAYGTNYTNAAR AGYCCNATGCARATHATGATGGCNGTNGAYGCNGARCARMGNAAYGARYTNGARTCNATG ATHGARGAYYTNGARGARGARAAYAARACNYTNCARGCNGARTAYGAYMGNYTNCARATG GCNGCNMGNGAYMGNTCNGAYCCNATGACNTCNTCNMGNATHTCNGGNGGNGAYAAYGGN GGNGTNGCNYTNACN---MGNGAYGARGARATGYTNGARGARGCNAARYTNYTNMGNCAY CAYAARGGNMGNYTNGARGCNMGNATGMGNGTNYTNGARGAYCAYAAYACNCARYTNGAR GCNCARYTNACNMGNYTNMGNCARYTNYTNGARCARGCNCCNGGNGAYMGNAGYTAYYTN TCNYTNGAYTCNTCNGCNMGNACNACNCCNATGACNACNCCNTCNTCNTCNCARAGYTCN TTYCARYTNAGYTCNTCNMGNTAYMGNATGGCNCCNGCNYTNGARTCNACNCCNCARACN AAYGGNCAYAGYGCNATGAGYYTNACNGAYGAYCCNGAYYTNAGYGGNATHATHGCNGAR GTNAGYAGYCCNCCNCARTAYAAYCCNGCNMGNAAYAAR---TCNAAYGTNGGNGAYYTN TTYAAYATHGCNGGNGARYTNGGNGAYGTNGTNGGNTCNYTNGTNACNGTNATGACNGAY AARGAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CARACNAAYAGYTCNTCNTCNCCNAARAARAARMGNAARAARAARGARAARGCNAAR TCNGGNGGNGARMGNAAYGCNGARGGNGARAAYAARCCNGARTCNACNMGNATHAAYAAR GCNYTNAAYTAYYTNYTNGTNTGGAARAAYGAYMGNAARTCNTGGAARTTYAARAARAAY YTNCARGCNTCNYTNYTNAARGCNGTNTAYAAYCCNATHATHATHCCNGAYGAYAARTTY GARATHYTNYTNYTNTAYYTNCARGGNGCNAARGGNGTNGCNMGNGARAARYTNAARAAR GAYGCNATGGGNATHATHAARGARGAYGCNGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNAAYAGYTAYYTNCCNTGYGAYGAYTTYATGAARTTYCARGAYGCNYTN AARAARYTNMGNYTNATGGAYGAYMGNATHATHCAYGCNYTNAAYAARGGNATHCCNACN CARTCNTTYCARGGNAARGTNGAYACNTCNTCNAAYTGYAARCAYATHTAYGAYGAYATH CARACNTCNTAYGAYCAYMGNGARAARTCNATHCARCARTGYATHMGNYTNGTNAGYGAY GAYGTNAARAARYTNAAYGAYMGNMGNCARCARGAYCCNGAYAAYATGGARGTNATHAAR TCNYTNMGNMGNGARCARACNAARYTNMGNYTNATGCARCARGARATGAGYGTNGARGAR GTNGTNAARGAYMGNACNYTNMGNGTNATHACNAARAARTGYGTNGARATHGCNGGNYTN TGYCAY------------------------------GAYYTNGGNCAYGGNCCNCAYTCN CAYATGTTYGAYGGNAARTTYATHCCNYTNGTNACNAGYATG---GAYTGGGARCAYGAR AARGCNTCNYTNGCNATGYTNGAYTAYYTNYTNGARGAYAAYCAYYTNATGAARGGNATH GGNATHYTNMGNAARAAYGGNYTNGAYAAYACNGAYATHATHTTYATHAARGARYTNATH AAYGGNCCNYTNGAYAARAAYGAYMGNGAYTGGCCNTAYGAYGGNMGNGAYAARAGYAAR GCNTAYYTNTAYGARATHGTNTCNAAYAARAARACNGGNATHGAYGTNGAYAARTGGGAY TAYTTYGCNMGNGAYTGYYTNCAYYTNGGNATGGTNAAYAAYTTYGAYCAYAARMGNTTY ATHCARTTYGCNMGNGTNYTNAARGTNGGNAAYAARTGGCARATHTGYGCNMGNGAYAAR GARATHGGNAAYYTNTAYCARATGTTYTAYACNMGNTAYAAYYTNCAYMGNTCNGCNTAY CARCAYAARGTNGCNTGYGCNTGYGARATHATGGCNGTNGAYGCNYTNATHAARGCNAAY GARGTNTTYGCNCAYYTNCCNAAY---TAYMGNATGAARYTNTCNGAYGCNATHCAYGAY ATGAARACNTAYGTNAARYTNACNGAYAAYATHYTNTGGGARATH---ATHTCNGARGAR GARAARYTNAAYCCNGCNAARGARATHYTNGGNMGNYTNTTYMGNMGNGAYATGTAYMGN TGYYTNGAYGARMGNAARAARGARYTNAAYAARACNAARATGGARYTNGTNAAYTCNYTN MGNGAYAARATGATHGAYATHTCNCARAGYCARGAYCCNGARYTNCCNCCNYTNAARGAR TTYMGNYTNCARATHGTNTAYATGGAYTTYGGNAARAARGAYAARGAYCCNYTNMGNGAR ATGMGNTTYTAYAGYAARTCNGAYTTYAAYACNCCNAARGARGGNTCNAAYCCNGGNYTN YTNGTNCCNCARCARTTYGTNGAYAAYYTNYTNMGNGTNTAYTGYTGYGTNAARGGNACN GARCARMGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARTTYAARAARAARYTNGARTCNTCNAAYACNGAY GAYATHAARAGYGGNAARATHGCNATGCAYYTNGAYYTNGTNAARCAYTCNGTNMGNACN CARYTNAAYGAYYTNAARYTNAARGARATHAAYMGNYTNACNGCNYTNGCNAARYTNCAR YTNCARGCNAARAAY---------------GARATHCCNGAYCAYYTNGAYGTNMGNAAY ATGAARACNTTYGARGTNAARGAYYTNGARGCNYTNATHCARAARACNACNTCNGAYYTN GARAARYTNGAYGARCARMGNMGNAARGARTTYAARGARTAYGARATGGARAARAARTTY GARCARGARGARCAYYTNAARAAYYTNAAYGARGARGARMGNCAYAARGARGARGARMGN YTNGAYGARYTNAARAARAARCAYAARGARCAYCCNAARATGCAYCAYCCNGGNAGYAAR GGNCARTTYGARGARGTNTGGGAYAARGARGAYGGNTTYGARGAYCARGAYTTYGAYCCN YTNACNTTYTTYYTNAARCAYGAYATHGAYGGNGAYCAYGARTGGAAYATHGCNGARGTN GARGCNGTNYTNCARMGNGARYTNGGNAARGTNTAYGAYGAYGARAAYTCNCCNGAYGAR GAYGAYCCNGTNGARAARGARGARGARATGAGYMGNATGMGNGARCAYATHTTYAARGAR ATGGAYAARGAYGARAAYAARMGNATHACNAARGARGARTAYATHGCNTAYACNGGNCAR CAYGGNGARAAYCCNGARTTYGGNAARGAYGARGGNTGG--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNAGYMGNYTNTCNAGYATHAARMGNAAR GTNGARGAYYTNAARMGNGGNGGNAARCARMGNAARYTNTCNGGNGGNGARGARGTNACN TCNACNAGYGARAGYAAYATHGCNGTNGAYAARGGNCCNGARGAYCARYTNMGNYTNCAY GCNATHAARATHAARTCNGCNGARGARMGNGCNAARGARTCNYTNYTNGAYATHGARACN GTNCAYAARTAYTGYAGYCARYTNTTYCARTTYAARACNATHGTNGTNAARAARTAYMGN ACNTGGMGNGARMGNMGNAARCAYYTNGGNGGNMGNGAYMGNAGYCAYMGNCCNGARTTY CCNTCNTCNACNMGNYTNATHACNTGYCCNATHGCNAAYAAYGCNAAYGGNGCNTCNGGN GTNGGNAARAARAARGARTTYTTYYTNAAYCCNTCNGGNAARTCNTTYYTNTGYATHYTN CAYGARTAYATGCARMGNACNYTNAARATHCARCCNACNTAYGTNTTYAARGARATHGAR AAYTCNAARACNCCNTAYGGNGCNACNGTNATGATHAAYAGYATHGARTAYGGNACNGGN TAYGCNTCNTCNAARAARACNGCNAARCARGARGCNGCNAARGARACNYTNAARATHYTN ATHCCNGAYYTNTCNACNAARATHTCNGAYCARGARYTNAARCAYACNGTNTCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGGCNGCNTTYGGNYTNCAYYTNGGNGCNTGY TCNGCNTGYYTNGCNGTNCAYAARGAYGGNAARACNGARGTNATHGCNAAYGAYYTNGGN GAYMGNGTNACNCCNGCNGTNGTNGCNTTYACNGARAAYGARACNTCNGTNGGNGCNGGN GCNAARCARGGNGCNATHMGNAAYGCNGGNAAYACNATHGCNCAYGTNAARCAYATHATH GGNAGYAGYAGYAAYGAYCCNYTNGTNCARGARTAYATHCARAAYCAYCARGTNGAYGTN GGNAGYGAYAARGGNTCNGTNGTNTTYAAYGTNGARCAYATGGGNAARAARGTNAARTAY ACNCCNAGYAARATHATGGARYTNATHTAYAGYAARATGYTNGARACNGCNCARAGYAAY AGYGGNGGNGGNMGNAARGAYGCNGTNYTNGCNGTNCCNTCNGAYTTYTCNCARAARCAR MGNGAYYTNYTNAGYGAYGCNGCNACNAARGCNGGNTTYAARGTNYTNMGNGTNATHAAY GARCCNTCNTCNGCNATGYTNGCNTTYGAYGCNGGNCARTAYGAYGAYACNGAYAAR--- TTYAAYACNYTNGTNTAYMGNYTNGGNGGNACNTCNCAYGAYGCNACNATHGTNAGYGTN GARCAYGGNATGTAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CCNACNCCNCCNGTNTTYCCNGAYGCN TAYAGYATHTCNTTYTCNGARGTNGAR---------------TCNATGTTYGGNTTYAAR ATHACNTCN---AAYAAYGGNACNTGGTAYTAYGAYTTYGCNAAYMGNMGNGCNMGNTAY GAYCAYAAYMGNGGNCARYTNAAYAAYTTYTGYGAYTTYCAYAARYTNAGYACNTGGGAY CCNTTYGCNGGNTGYMGNYTNTAYTTYACNCCNACNGAYGAYTTYATHGTNTAYTAYCCN GGNACNAARAGYTGYTGYMGNYTNTGYGGNMGNAAYGARGGNTGYACNGTNYTNMGNCCN GAYTGGYTN---GTNGGNTCNAARGTNATHTCNGTNGARAARATHAAYGGNGTNACNTGY TAYGGNTGGGGNAARAARGGNGCNGTNGCNGCNGCNGAYACNTGGTAYACNACNGCNGAY GGNATHCCNTGYMGNTAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYCCNMGNGAYCARAAYGCNATHACNAAYACNTTY TAYYTNACNAGYAARAGYGAYTGYGGNGAYGAYYTNAARAAYATHTTYGGNCARGARGCN TAYGTNAARGGNTAYGAYYTNGGNAAYYTNGCNACNGGNCCNACNTCNTGYACNATHAAR ATHACNTCNACNTCNGTNTAYACNGGNGTNCARYTNGARYTNYTNATHAAYGCNATGAAY ATHYTNGAYTGYGAYACNCARYTNACNATHTAYGAYGGNCARGAYAGYGGNYTNYTNGGN TCNTAYGAYTGYMGNAGYAGYCARAAYATHAAYMGNMGNTCNYTNYTNACNTCNGGNGAY ACNGTNACNTTYATHYTNAGYMGNAARAAYCCNGAYAGYACNAGYTTYGAYATHGAYGTN MGNATHMGNCCNYTNACNAGYGGNGGNGGNAAYCCNGAYAARCCNGGNAAYCAYAAYCCN TTYGAYTTYGARAARTTYGAYCARGAYGCNATHGTNGGNATGATHGCNGGNTTYTAYGCN YTNGTNGCNGTNATHTGYATHGCNGTNGTNATHTAYTTYTAYTGYAAYTTYAAYGGNAAR ACNAARAARTGGGARACNCAYCARYTNCARACNTTYAARACNGTNACNAGYTTYGAYGCN MGNACNCARGARTCNCAR------GCNCCNTGGTCNGTNGGNACNGCNAGYCARMGNGGN CCNACNAGYCARTAYACNMGNTCNTTYACNGAYACNTAYTCNMGNGGNCCNGCNGCNMGN ---AGYGARGAYGGNYTNAGYGAYGTNTAYGAYCAYGAYGARAARTTYCARAARMGNAAY YTNATGACN---CARMGNGAYMGN---MGNAAYGGNMGNGAYMGNATGGCNTCNCARAAY TCNGTNTAYACNGAYGAYGARCCNGARGARACNTTYAARGARAARGTNATHACNCCNMGN GTNMGNCCNGGNGGNMGNAARAAYCARMGNCCNCCNTCNTTYGARGARGCNACNMGNGAR AGYTCNGCNGARGARTCNTCNGARGARGAYGARGARACNGARGARTCNAGYGAYGAYTCN ACNMGNAARMGNYTNACNACNTCNTCNGAR------------GGNAGYTAYACNGARACN GARTCNGAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARYTNGGNGCNYTNGTNGAYYTNACNTAYACNACNAARTAYTAY AAYAGYGGNTTYTTYACNGARMGNGGNATHAAYTAYAARAARGTNTAYACNCARGGNCAY GTNATHCCNAGYGAYACNGTNTAYTAYGARTTYGCNAGYGCNATHCARGARYTNGARAAR GARGGNGARGTNATHTGYGTNCAYTGYACNCAYGGNYTNAAYMGNTCNGGNTAYYTNGTN TGYMGNTAYYTNATHGARGARYTNGGNATHAAYCCNGAYGARGCNATHAARYTNTTYGAR AAYGCNMGNGGNCAYAARATGGARMGNGARAAYTAYATHCARGAYYTNATGMGNMGNGGN YTNGGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY GCNGGNYTNTAYACNTGYGTNGCN---AAYGGNTAYGGNAGYATGAGYATHAAYTAYACN GTNATHGTNYTNGAYGARGARAAYCARMGNTTYCARGARAAYGAYAARYTNYTNGTNCAR TCNCCNGAYGARGAYATHACNAARGARGCNGCNGCNCCNACNTTYCCNGAYATGGARAAR ATGYTNGARAARAARAAYCARYTNAARCCNAARGGNTCNTCNYTNMGNYTNGTNTGYAAR GTNMGNGGNAAYCCNCARCCNCARGTNAARTGGCCNAARAAYTCNYTNCCNTAYGTNCAR MGNMGNCCNCAYTCNACNYTNAARYTNCAYAGYGTNACNGGNAARGAYAGYGGNAAYTAY ATGTGYGTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CAYGTNYTNGGNTGGCARGCNGAYTCNYTNGARAARCARGCNTGYAARYTNTGGGARGAR ACNATGGTNAAYGGNAGYYTNCARTGYAGYCARGTNTCNGTNCARYTNAARAARGCNMGN TCNTTYGTNMGNATHGCNGARATHCARTCNACNYTNCAYGARCARMGNATHATGTCNTCN GAYCARYTNMGNCAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGYTNGARGARGGNAGYGGNGCNATGGAR AARAARGTNYTNACNMGN------CARTCNCARGGNCARTGYAARAAY---AGYGCNYTN TGYGARMGNAARTCNGAYTCNACNTCNGGNMGNCAYGGNTTYTCNMGN---MGNTCNTTY CCNAAYGGNGGNGCNAARTCNCARGAYGCNTCNCARGCNCCNMGNCCNATHCCNGTNCAR AARTGGGAYMGNACNCCNGGNGAYMGNMGNCCNMGNCARMGNATHAGYCAYGAYCAYMGN CARMGNGARAARGTNGARGARAAYGARACNATHTAYGAYGTNATHAGYACNGGNTCNMGN AARGGNAAYGCNAAYCAYYTNYTNAAYTTYAARCAYMGNCCNCAY---CARGTNCARGCN GAYGAYCAYMGNTGGCAYTCNGGNMGNGGNTCNCAYGGNCAYGGNGGN------AAYAAR MGNTTYGCNCAYTAYAARAARGARCARTTYYTNCARGCNAGYTGYCAYTTYGTNGTNMGN GAYACNMGNGAYTAYGTNGARCARGCNTCNGAYTCNGAYGCNYTNGTNGAYTGGMGNATG GTNGARYTNGTNMGNAGYTTYTCNACNGARCCNGTNAAYTGYCCNATHTGYYTNCARACN YTNTCNGCNGGNAARATHACNAARTGYGGNCAYACNTAYTGYTGGCCNTGYATHYTNCAY TAYATHAARYTNGGNGARCARGAYTTYGGNAARTGYCCNATHTGYTTYGAYAAYATHGAY YTNGARGAYYTNAARAGYGTNCARTGGYTNGARGTNCCNGAYTAYAARGTNGGNGAYGAR ATHGARATGAARYTNATGMGNAARTCNAARGGNAGYGTNTTYTCNGCNCCNGCNCCNCAR TGGCARGAYMGNAARGGNAARCAYATGCAYATGGAYGARGGNGARAAYACNAARTAYATG AARYTNYTNGTNGCNTCNTGYGAYCARATHCARTCNAAYGTNATHGAYGTNGARMGNGCN GCNYTNATHGCNCARATHGARGAYGCNGARGARGARGCNGARGTNTTYATHAAYATGGCN YTNGARYTNYTNAARGTNMGNGARCARYTNYTNAAR------------------------ ------------------------------------------------------------ ------------------------------------------------GARGTNTTYCAR GAYAGYGCNTTYGAYAARATHCAYATHCCNGGNYTNGGNYTNAGYCARTTYAGYACNAAR CCNAARGAR---------------CARCCNGGNGTNGAYMGNGAYAGYGTNMGNAAYTCN TCNTGYAGYGARTCNGTNGARGGNGARGAYAGYGTNGTNGGNGARGGNGARACNGCNGAY YTNYTNGAYTGYACNATGGGN--------------------------------------- ---TAYCCNAGYAGYGGNACNGARCARGCNTGYTCNTCNTCNTCN--------------- ---------------------------TCNACNYTNATHGAYTCNGTNGCNGARACN--- ---------------------GAYTCNCCN------YTNGAYTCNGGNCCNCCNCARTCN AARACNTCNCAYACNYTNAAYACNAARGAYGAYTAYTTYTTYTAYCARGCNTCNAGYGGN CARCAYATHTAYYTNAAYTCNYTNAAYGCNCARTGYYTNGCNAARGARTAYAGYTCNYTN GARAAYAGYCCNGGNACNGTNACNGGNACNATHGTNGCNATHGAYMGNATHTTYATGACN GARGAYGTNMGNAARMGNYTNMGNTAYYTNAGYCAYATHCCNYTNACNTGYGARTTYCAY GTNYTNGARYTNAARYTNAARCCNGAYYTNGTNAGYAARGARACNYTNAARTTYTAYGAR GGNTCNTTYGAYAARMGNMGNAARATGMGNCARCARAARGCNMGNGARGAYMGNAARMGN GAYMGNAARATHGARATGGARCARMGNMGNAGYTAYGGNYTNTAYCCNGGNATGCARATH CCNYTNGAYAGYYTNGARCARTTYCCNTCNTAYYTNTCNGCNAGY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNGGNCCNGAYYTNGAYGAR GARAARGAYTCNGTNGAYACNATHYTNGAYAAYGARGARTAYGARMGNAARCARYTNGAR AARYTNGARGAR---GCNGARGARAAYTTYAAYAAYAARGCNAARCCNCCNACNGCNCCN TCNAAYATGGTNYTNTTYTAYACNTGGATGATHGTNGCNGTNYTNATHATHGTNGTNGGN GTNTCNGCNTAYCARGCNAARTGYCARGGNYTNATGTAYAARGGNAAYMGNCAYCARACN MGNGGNGARGAYMGNAARMGNYTNGTNGAYAAYGARTAYGTNGTNACNATGTTYGAYYTN CCNTGGGARCARGTNYTNTGYMGNAAYGTNYTNAAYTTYYTNAGYATHTCNGAYYTNTTY CAYYTNMGNTCNGTNAAYCAYAGYTCNYTNTGYYTNGTNGARACNTAYTTYAGYYTNCAR TTYAAYYTNAAYYTNTGYAAYMGNGGNAARGAYYTNACNCCNGGNGCNTTYTCNATHATG ACNMGNGAYAGYACNTGYYTNMGNACNYTNAAYYTNMGNGGNGCNAARTAYGGNYTNACN AAYGAYGTNTTYYTNCCNGTNATHTCNAAYAAYCAYMGNYTNGAYAARATHGAYATHAGY GGNTGYACNTCNYTNTCNGGNTGYGTNYTNTAYGCNATHGGNGCNAAYTGYCCNAARYTN AARCARYTNYTNYTNMGNGAYTGYGTNACNTTYAGYGAYGAYAAYTTYYTNTCNTTYATH TGYGCNCARCAR------CCNYTNGARTAYYTNGAYATHTCNGGNTGYTGGAAYYTNGGN GAYGARYTNYTNGTNAARYTNGTNCARTGYTGYCCNAARYTNAARCAYYTNYTNYTNGGN AARYTNTAYGGNYTNTCNGAYMGNGCNGTNTGYGCNATHGCNCAYTCNTGYCCNGAYYTN GTNTCNYTNAGYYTNTAYGGNTGYTGGMGNGTNACNGAYGAYGCNATHAGYATGATHGCN GCNTAYTGYTCNAARYTNAARYTNYTNCAYGTNAARGARTGYMGNGAYGTNACNGARAAR AGYYTNGCNCCNYTNMGNCARMGNAAYGTNAARGTNGAYAARCCNGGNCCNCCNTCNTCN TAYYTNAAYMGNYTNGARTAYYTNAAYAAYGCNCARMGNATHAAYGTNATGYTNGAYAAR ATHGTNYTNTAYAGYTAYTTYMGNAGYTCNGCNAGYTGGMGNGTNMGNATHGGNYTNGCN YTNAARGGNYTNAARTAYGARTAYGARGCNGTNCAYYTNGTNAARGGNCARCARMGNTCN GARGARTAYAARAARYTNAAYGCNATGGGNTAYYTNCCNACNYTNAARATHGAYGGNYTN ACNYTNGTNCARTCNYTNCCNATHYTNGARTAYYTNGARGARMGNAAYCCNGARCCNCCN ATHYTNCCNAARGAYCCNGCNGCNMGNGCNAARGTNMGNGCNGTNGCNGARGTNATHAAY AGYGGNATHCARCCNYTNCARAAYYTNAARGTNYTNCARAARGTNGGNGAYACNAARATG GARTGGGCNGARCAYTTYATHGARGCNGGNTTY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGTCNGAYAARYTNACNACNMGNGTNGTNCARGTNACNAAY ATHGCNCCNAGYTGYACNAARGARCARYTNMGNACNYTNTTYGGNTAYATHGGNMGNGTN AARGARYTNGARATGTAYCCNCCNGAYGGNGCNGARGGNGCN---GTNACNGCNMGNGTN GCNTAYGTNGARTTYGAYGAYTCNGTNACNACNGGNGTNGCNYTNCAYYTNAGYAGYACN GTNTTYATHGAYMGNGCNATHACNATHGTNCCNGTNATGGAYGGNAARATHCCNGAYGAR AGYTCNGCNYTNCARYTNACNCCNTCNGCNGTNGCNGGNATGYTNCCNGGNCARCCNACN TGGCCNGCNAAYGTNGTNTCNCARGTNACNGGNYTNGGNGCNAAYCARGTNATHATGACN AAYGAYCCNMGNYTNACNTCNYTNGGNYTNCCNCARTAYCCNCCNYTNCCNGCNACNACN GAYCCNAGYAARATHGARGARATHMGNMGNACNGTNTTYATHTCNGAYYTNGAYCARAAR GTNACNCCNGARATGYTNYTNTCNTTYTTYTCNCARACNGGNGARATHAARTAYATHMGN ATGGCNGGNGAYGARAAYGGNCCNACNMGNAAYGCNTAYATHGARTTYACNGAYCARMGN TGYATHGCNCARGCNYTNAGYTAYAAYAAYGTNGTNTTYCARGGNMGNACNGTNAGYGTN AARCAYGCNACNACNAGYATHGTNAARCCNTCNCCNAARTCNGARGCNTCNCARMGNGAR ATHGAYGAYGCNATGAARAARGTNAARGARGCNTCNAARYTNATHTCNGCNGCNGCNAAY AGYGARMGNGARGGNTCNMGNTCNCCNACNMGNAAR------MGNTCNAARTCNMGNGGN MGNAGYMGNTCNCAYTCNAARTCNMGNAARTCNMGNTCNMGNTCNMGN---GGNMGNMGN MGNMGNAGYGTNTCNAARTCNMGNAARMGNTCNMGNTCNMGNMGNMGNTCNCCNMGNMGN TCNMGNTCNCCN---MGNMGNMGNMGNTCNMGNTCNMGNGGNMGNGARGCNCCNACNGCN CCNCCNGTN------------ACNMGNGAYMGNMGNMGNTCNAARACNMGNTCNCCNATH MGNMGNAARMGNTCNMGNTCNMGNTCNMGN---------MGNMGNTCNMGNACNCCNCCN AARTCNTAYAGYMGNMGNAGYMGNTCN--------------------------------- ------------------------------------------------------------ ------AARGAYMGNAARGARAARGGNAAYGGNAARGCNGGNGGNAAY------GGNMGN TCNCCNAGYCCNGTNAARGCNMGNAARMGNAGYGCNACNCCNAARMGNMGNAGYMGNTCN MGNTCNCCNAGYMGNMGN---AARMGNAARMGNTCNACN------------TCNAARAAR MGNTCNMGNTCNMGNAGYGGNTCNMGNCAYMGNTCNMGNAARGAYAARAARMGNAGYMGN AGYMGNGAYMGNAARCAYGARAGYAGYAARAARAARAGYAAYMGNGAYAARGARGARAAR AARAARGAR---AGYTCNTCNTCNAARATHAARMGNGAYTAYGAYGARGARGARAARGGN TTYGCNAGYGCNAGYGARCARATHGARAAYAGYGARGARGCNGCNGGNTCNGGNGGNTCN GARGAYTCNCCNATHCCNCCNCCNGTNYTNGARAARGAYACNGAYCAYCARGCNGTNGAY ATGGAYATGAGYGAY--------------------------------------------- ------------------------------------------------------------ AGYYTNATHAARTAYCAYGGNAGYGARGGNYTNYTNAAYYTNCARTGGYTNGCNGAYCAR AGYGCNAAYGCNMGNGCNTTYGAYTTYGARATHGAYGARCAYTCNGTNTCNACNMGNMGN CCNGAYGGNCARYTNGARACNACNACNGTNGTNACNGCNACNGTNGTNATHCAYGARGAR GAYGARGARGGNGARGGNGCNCARGAYGAYYTNGAYGGNAAYGGNCARGCNGARGGNATH GCNCCNGARAARGARGARYTNTAYGGNAARATHGCNATGAARYTNATHGARATGGCNGAY ACNTAYGGNGGNAGYYTNTCNGAYGCNGARGARGAYGGNGCNACNGCNATHTAYGAYGCN CCNYTNACNGAYYTNGARAARGARATHATHGCNTGYYTNMGNTCNGGNGGNGAYAARTAY GGNAARAARATGGARGAYCARYTNGAYGCNATGAARGCNGCNGTNGCNGAYAAYGCNTAY GAYMGNTTYMGNAGYACNATHGAYAAYTCNATGGGNCAYGARYTNAGYTGGAAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNGCNGCNATHGCNGARGARGCNTCNMGNYTNGGNGCNCAYTTYTTY GTNAARTAYCAYCCNGGNGTNTGGACNAARAARACNNNNTAYTAYAAYTGYTGYGAYCAR TGYGAYMGNAAYGCNATHGGNTGYAARTGYGAYAAYGTNCARCARMGNAAYYTNGCNCCN CCNATHCCNCCNCCNMGNCCNGAYCARAGYAAYMGNGTNGARTAYATHGCNYTNTTYGAY TAYGARCCNACNGARGARGGNGAYYTNGARYTNATHCARGGNGARACNTAYATHATHYTN GAYAARAGYGCNGARAAYTGGTGGTAYGCNGARAAYCARGARGGNAARAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNACNTCN TCNGTNTTYGGNGCNACNCARCARGGNTCNAGYCARAGYGTNTTYGGNGCNACNGCNGGN TCNACNAGYTCNGGNGCNGCNACNCARCCNTCNGCNGCNCCNGCNTTYGGNACNGGNGCN CCNGCNGCNACNTCNCCNTTYGGNGGNTCNAAYGCNTTYGGNGCNCCNAAYAARCCNGCN CCNTTYAAYAGYTCNTCNATGAAYGCNTCNCARGGNTCNAGYTTYAAYTTYACNGGNAAY CARCCNGGNTTYGGNGCNCARACNGCNAGYGCNGCNTCNTCNGGNTTYAAYTTYGGNCAR GCNGCNCARCCNGGNTCNMGNYTNAAYGGNGGNTTYAAYTTYGCNGCNGCNGCNCCNCCN CCNGCNAAYCCNGGNGGNTTYAAYTTYACNCCNGGNGGNTCNACNCCNACNCCNTCNTTY AAYTTYGGNGCNACNCCNAGYACNCCNAAYATGTTYACNCCNCCNACNCCNGGNACNGCN CAYMGNCCNMGNGCNACNGCNMGNMGNGGN---MGNMGNGGNGGNMGNCARATHTCNCAY ATGATHGCNTTYATHGAYCARGARGCNTCNGARAARGTNGARGARATHGAYYTNAARGCN GARGARGARTTYAAYATHGARAARGGNMGNYTNGTNCARCARTCNMGNGTNCARATHATH GAYCAYTAYGAYAARAARGTNAARAAYGTNGARYTNCARAARAARATHCARAAYTCNAAY ATGCARAAYAAYGCNMGNYTNGARGTNYTNMGNAARAARGARGARTAYGTNAARGARGTN ATGGAYGARGCNMGNGARAARYTNMGNMGNYTNGCNATGGARAAYCCNGARGARTAYAAR CAYYTNYTNYTNMGNYTNATHATGCARGCNYTNATHAGYYTNATGGARCCNAARGTNAAY ATHMGNTGYAARMGNGARGAYATHCARATGATHAARAAYGCNATHCCNAGYYTNGARAAR GARTAYAARGARATGYTNAARGGNAARTAYCCNYTNCARYTNGTNGTNGAYGARGARAAR TTYYTNTCNACNGARACNTGYGGNGGNGTNGARYTNCARGGNATGAAYGGNAARATHGTN GTNGTNAAYACNYTNGAYGARMGNATHTCNGARTCNGTNACNGGNGCNTAYGTNYTNTGY YTNYTNTAYCARAAYMGNGTNCAYCARTAYMGNATHYTNCCNGAYAARGAYGGNAARATH TCNGTNCARTCNGARGGNGAYATGCARCCNCCNTCNTAYTGYGAYAGYYTNGTNACNTCN TAYATHAAYMGNGGNGARAARAAYGGNYTNGTNTGYGCNYTNMGNAARGCNGTNGGNCCN GARGGNGCNGARACN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNGTNGTNTAYYTNCARMGNGTNGARTCNTTYAGY GCNTGYCAYMGNYTNCAYTGYCCNCAYYTNACNGAYGARCARAAYACNACNATHTTYGGN AARTGYAAYCAYCCNAAYGGNCAYGGNCAYAAYTAYAARGTNGARGTNACNYTNMGNGGN CCNGTNCAYCCNGARACNGGNATGGTNYTNAAYATHGAYGAYYTNAARAARTAYATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AAYCARGTNACNGTNAAYGGNCARACN TCNTTYGTNYTNGTNGAYGCNCARAAYAARCCNATHCARYTNCCNCARGGNATHCARGTN ATHAAYYTNCCNCAYCARCARYTNTCNGGNCARTCNATHCARATGCCNGGNAGYGAYACN GGNGAYGARCCNYTNTAYGTNAAYGCNAARCARTAYCAYMGNATHYTNAARMGNMGNCAR GCNMGNGCNAARYTNGARTCNGARGGNAARATHCCNAARGARMGNCARAARTAYYTNTAY GARTCNMGNCAYMGNCAYGCNYTNAAYMGNGCNMGNGGNTCNGGNGGNATHTTYGTNGGN CARACNAARGCNYTNGAYGTNATHYTNGTNAGYGGNMGNCAYAARATHCCNACNAGYYTN GAYACNTCNMGNTCNCCNYTNAGYGARGAYCAYYTNACNGTNAAYCAYYTNTGYCAYGCN GTNCARCARCAYACNAAYATHAARCCNGARGCNCARAARYTNATHTTYMGNGGNMGNACN YTNTTYAARACNTAYGAYCCNGARGGNGARAGYYTNMGNAARAGYYTNTCNTCNGTNGGN ATGAARAAYGGNGAYMGNGTNATGGTNTTYGGNAARCCNGCNGAYGARGARAARGGNGGN MGNGARGAYAARGGNGAYAGYGGNAGYGARYTNYTNAARGTNYTNGAYCARCAYCARGCN MGNGTNGARGARYTNTGYGTNGTNTGYAGYAAYATGGTNTCNACNGCNCAYAGYCCNGGN ACN---GTNGARGARTGGMGNAARCARMGNAARTTYTTYYTNGGNCARTCNGARYTNTGY ATGCARGARYTNACNMGNYTNGAYGCNACNCCNGGNGAY---TCNTCNAGYCARGGNTAY AARACNMGNMGNAARGCNYTNGTNAAYMGNYTNYTNGARAAYATGACNGTNTGYGAYAGY CARGTNTCNMGNYTNTCNTCNTCNATHGARGCNTGGGARATGAAYGARATHATHMGNMGN YTNGTNGGNAAYTTYGAYMGNYTNGARGTNYTNGTNTTYGAYGARGAYACNATHYTNAAY AARCCNGTNGARGARTGGCCNATHGTNAAYGGNYTNGTNTCNTTYTTYTCNCAYGGNTTY CCNYTNGARAARGCNATHGCNTAYAARGARYTNMGNAAYCCNTTYATHGTNAAYGAYYTN GARATGCARTAYACNYTNCARGAYMGNMGNAARGTNTAYGCNATGATGCARGARAAYAAY ATHCCNCAYCCNMGNTAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARMGNGARATHGTNGCNCARAGYATGACNTTY YTNYTNGCNGGNTAYGARACNACNAGYGCNGTNYTNGCNTTYTTYTGYCAYGARGTNGCN AARCAYCCNCARGTNCARGARYTNYTNTTYCARGARATHAAYGCNAARATHGGNCARAGY AAYGTNGAYTAYGARAAYATHCARGAYATGCCNTAYTTYGAYMGNGTNTTYGAYGARGTN TGYMGNYTNTAYCCNACNGCNTCNATHATHACNMGNCARGCNGCNGARAGYMGNTGYTAY GGNMGNGTNAARATHCCNGCNGGNATGAAYGTNYTNGCNAAYGTNTGGGCNYTNCAYMGN GAYCCNGCNYTNTGGGARAAYCCNGARGARTTYMGNCCNGARMGNTTYGARGAYTCNATH GCNATGMGNAARTGYACNTTYYTNCCNTTYGGNGCNGGNCCNMGNCAYTGYATHGGNATG MGNTTYGCNACNATHGARGCNAARATHACNYTNATHAARATHATHAARCAYTTYCARYTN GARAARTCNGARGAYGCNACNGAYGAYYTNGARGTNMGNGGNGCNATHGTNGCNACNAAR GCNGTN------------GCNCCNGGNATGATGGTNGCNATGATGAARGGNACNCCNYTN GCNATGYTNAGYMGNYTNGTNTGYGGNATHMGNGGNTCNACNGGNAGYACNAARGGNTCN GCNGAR---TGYYTNCARATHGTNTCNGTNGGNATHCCNCAYGCNGTNGAYYTNYTNCAR GGNCAYAARTCNGGNGTNMGNACNACNCAYGCNGCNYTN--------------------- ---------------------------ATGGGNAARAARCAYAARCAYGGNAARCAY--- TCNTCNTCNAGYAGYTCNTCNAGYAGYAGYGAYTCNTCNGAYGAYGARTGGAARCAYYTN CCNAARCAYGARAARAARATGMGNAARAARTGGAARAARCARATGMGNAARGGNATGATG CCNCAYGGNGCNGTNGCNCCNTGGCAYGGNGGNCCNGCNTGGGCNCCNCCNATGAARGCN GGNAARAARGGN---CAYGGN---CAYGGNAARCAYGGNCAYGGNCAYGGNAARCAYGGN TCNGTNCCNGGN------GCNTAYCCNGTNGGNACNCAYCCNCCNCCNCCNACNGGNTAY CCNGGNGCNCAYGGNTAYCCNCCNCARAAYCCNGCNTAYCCNGGNCAY---AGYGGN--- TAYCCNGGNGGNGCNCCNCCNCCNGCNGGNTAYCCNCCNCCNAGYGGNTAYCCNCCNCAY GGNGGNTAYCCNGGNGCNCCNCCNCCNGGNGGNTAYCCNCCNGGNACNTAYCCNCCNCAY CCNGCNGCNCARTAYGGNCARCCN---CCNAGYGGNGCN------TAYGGNGCNCAYGGN GCNCCNTCNGGNCCNTTYCARGCNCCNCCNGGNGGNGCNTGY------CCNCCNTCNGGN TAYCCNCCNCAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ACNTCNYTNAGY CARGARAARATHACNYTNTCNCARMGNGCNGAYATHYTNCARGCNGARYTNAARGGNATH GARGARAARACNCARGCNGTNCARGGNGARAARCARAGYGCNGARATGAARYTNCARGAY AAYYTNGAYMGNTTYAAYGARATGGARACNGARAARATGGARATHTCNCARCAYGCNTCN GARYTNGARAGYACNATHAAYGAYYTNGTNGCNCARAARGARATGACNGARAARGARYTN AARGARGARATHMGNGCNMGNATHTCNGCNGARGARMGNYTNAARCARGCNGARMGNTCN YTNACNAAYYTNGAYCAYGCNGTNCARAAYCARTCNCAYMGNATHGARGARAGYGCNAAR GARGARATGAAYGTNAGYGTNAARAAYYTNAARAAYTTYTTYGARGAYYTNGCNGARGAR GCNAARATHACNTCNGAYAAYCCNATHATHATHMGNAAYGGNATGATGGCNMGNAARACN YTNGCNMGNMGNGCNAARACNATHMGNTAYAAYAAYAARAAYMGNTCNTCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATHAARGAYGGNGTNGTNCCNYTNGCNCARGAYGGNYTNGTNTGY ATHAARGGNAAYAAYTGYTAYAARCCNACNTGYGCNTTYGGNGARTTYGAYGTNAARTCN GGNTTYTGYCCNYTNTCNGAYAARCAYGCNYTNCCNGCNCAYYTNTTYAARAAYCCNGCN GAYMGNMGNCAYTAYMGNAARCAYYTNAAYAGYGAYCARGAYTCNGTNGAYTCNMGNMGN TCNGARCCNAAYTTYGGNMGNTTYTAYAAYACNAGYTAYYTN------------------ ---MGNYTNAAYAAYGGNCARAGYTCNGGNYTNAAYAARMGNGAYGCNAARAGYGGNTCN CAYTTYCAYMGNCCNCCNAAYTTYACNTAYGCNAARGARCCNCCNACNTTYATHAARAAR AARGGNACNGGNATGTCNGCNYTNACNTCNGTNACNMGNGTNGTNAARGTNMGNMGNAGY TCNTCNCCNGCNTAYYTNMGNAAYCARGARGCNGTNMGNATGAGYATGTAYCCNAGYGCN AARCCNAARCARCCNAAYGARCCNGAYAARATHGARMGNGAYGAYTGGCCNGGNCCNGCN TCNCCNGCNGCNATHYTNCCNGARATHYTNMGNCARMGNMGNMGNAGYMGNGGNGARAAR GARGAYGAYGAYGAYGARGARGARGTNMGNGARGAYCCNMGNATHCARMGNGARYTNAAR GARATHTCNAARATHAARGAYGARAGYGGNATHGGNCARGTNATHTAYMGNGARYTNGAR GGNYTNAARGCNAARCCNTAYCARCCNYTNGAYCCNTGGAARGCNTCNMGNGCNCCNAGY GCNAARTTYGARCCNMGNTAYMGNACNMGNTTYCARTCNCCNATGTTYGCNTCNCCNTCN MGNTTYYTNGAYMGNCCNMGNTAYGCNTGGGAYGAYAAYGAYATHMGNACNTAYMGNTCN GCNTCNACNYTNGCNAAYYTNCCNACNGCNAARCCNGGNTAYGGNCCNTCNTAY---ACN CCNMGNGCNGCNACNYTNCCNYTNGCNGGNGCNTAYGGNGCNMGNGAYGAYTTYMGNTTY TTYGARTTYGAYGARTCNGAYGAYMGNCCNAAYACNAAYYTNTCNTCNTCNACNYTNACN GGNGAYAGYAGYTCNMGNMGNCAYGAYACNTCNTTYGCNGCNTAYGARGGNCCNAGYATH CCNYTNYTNCARYTNCARAARAGYTCNTGGCAYGCNGARATHGARCCNCCNATHTAYGAY TAYGARMGNYTNAARATHACNAAYTTYGAYYTNCCNAARGAYGTNGAYATHAAYCAYYTN GARATHCAYYTNCCNAAYGARGAYTTYGARGARYTNTTYAARATGCCNMGNGAYMGNTTY TAYMGNATGGCNGARTGGAARMGNAAYGAYGTNAARMGN---------------GAYAAY YTNTAYTAYGCNTTYAGYACNYTNGARATGCCNACNATHGTNGTNGCNMGNACNACNGGN TAYGAYTCNGAYATGATHTTYGAYTGGGARMGNATHYTNAAYAAYACNTCNYTNGARGAY GCNATHAGYTTYACNGAYAARATHGARYTNGAYTAYAARTTYGGNATHGCNTTYACNAAR YTNATHGARTAYGAYGAYGTNCAYGAYGAYGCNGAYATHACNGARGCNAARAARCAYAAR GAYGARTGGAARACNMGNTAYTTYAAYGARACNATHTGGATGACNYTNGAYGTNGAYGAY AARAARAAYAAYTTYACNTTYAAYGCNACNGAYTAYGAYATGAGYCARTCNAGYACNAAY AAYGGNAGYYTNTCNTTYACNTTYMGNAGYCCNTCNAARGAYGGNMGNGAYAAYAARYTN CCNGCNCARMGNTAYACNGTNAAYGARACNYTNTTYGAYTTYMGNYTNCARAAYTTYACN CCNTCNTAYACNCAYTCNMGNTTYGCNYTNGARTTYGTNTCNGTNAGYYTNCAYACNAGY AARAARATGGAYGTNGAYACNATHAARACNATHGAYGAYGARTAYTCNCCNGGNGTNTTY YTNYTNACNAAYYTNYTNACNAAYCCNTCNGAYAAYTCNMGNTCNGGNTTYATGCARTGG AARCCNGTNTGYTAYYTNAGYGAYAGYMGNGGNMGNAARTCNAGYACNAARGTNAARCAY TAYGAYYTNGARAAYYTNGAYGARGAYGAYGGNYTNAAYGCNACNYTNYTNGCNGGNYTN TTYGGNAARGAYYTNTAYGAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TCNATHTTYGCNTTYGCN ACNCCNCCNAGYCCNGAYTCNTCNACNACNTTYTTYGTNMGNAAYTGYAGYTTY------ AAYGGNACNATHAAYCCNCCNGCNTCNAARACNTTYTCNTAYAGYTAYCCNTAYGAYYTN GARAAYACNTGYTTYGAYACNCCNATHTGYAAYGCNCCN---AARACNGTNATHMGNGGN AGYYTNTGYYTNYTNGARGGNTCNCARGCNTCNGCNCARTTYTAYGTNTTYGTNGGNGTN ATHGTNTTYYTNTAYTGYYTNGGNGCNYTNGTNYTNTAYATHTTYTTYGAYGARAGYTAY MGNMGNAAYTCNMGNATHGTNGTNGCNGAYTTYGTNGTNTCNYTNGTNYTNACNYTNYTN TGGATHATHGCNTCNTCNGCNTGGGCNGCNGGNYTNAAYGAYGTNAARYTNTAYACNGAY CCNGAYGAYGGNGCNATHTTY---GARMGNYTNGAYGARTGYAARCAYTCNGAYAGYGCN TGYTAYACNAGYAAYAAYGGNAAYTTYGCNTCNYTNAAYGTNTCNATHATHTTYGGNTTY YTNAAYTTYGCNGTNTGGGTNGGNAAYYTNTGGTTYYTNTAYAARGARACNCCNTGGTTY AARGTNCARGCNAARCCNCCNACNCARCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CCNGARCAYCCN ACNTAYTCNTGYACNTAYMGNMGNYTNGTNYTNGGNCARAAYYTNTCNYTNCAYATHGTN ATHAAYCCNMGNCARCCNTCNAGYYTNCCNGARTGYMGNATHYTNGGNGCNGARTCNGCN GCNATGCCNYTNAARGARAARYTNAAYATHAAYYTNCAYYTNTGGGAYYTNGAYMGNTCN YTNYTNAAYAAYYTNCARGARGTNATGGARATHGAYTTYCCNACNAARTCNGAYTCNAAY ATHGARGAYGTNAGYGTNGAYTGYAGYATHTGYTAYAGYCAYGARYTNGGNAGYGARATH YTNGARATHGTNTGYYTNCAYCCNCARTGYAGYCARACNTTYCAYTAYACNTGYYTNTAY GARTGGYTNTGYAAYAGYGGNTGYMGNCARAGYTTYAAYTAYYTNATHGGNGARTGYCCN TTYTGYACNAARCCNATGMGNYTNAARATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GGNYTNGGNTAYGGNTCN--- ------GCNAGYGARAGYGARACNGAYGGNCARAARGAYGARGAYTCNGAYAGYGAYYTN GAYGARAARATHMGNMGNAARAARGCNGARTTYGCNAARMGNCARAARATHTTYAGYGAY GTNGARGAYGAYGAY--------------------------------------------- ---------------------------GAYGAYMGNGARTCNYTNTCNYTNAAR------ ------------------AARACNAARGARGARAARMGNATGAARGARGGNAARYTNGAY GTNCAYATGGGNAARGAYGAYGAYAARAGYGAYMGNMGNCARACNGAYCAYAAR------ ---GTNGARAARGAYGTNAARCCNGAYMGNMGNGAYAGYAGYAARGARACNAAYGTNAGY AARCCNCCNCAYCARAAYMGNTGGGAYTCNAARCARAARCCNGAYAGYAGYAAYAARGAR AAR---MGNAARAGYGTNGAYGARAARGCNGARGTNMGNGTNAARGARGAYAARTCNCAR ACNGTNGAYGAYAARAAYMGNTCNAARMGNAAYMGNAGYAGYAGYGGNAGYAGYAGYGAY AGYAGYAGYGGNAGY---------AGYGAYTCNTCNTCNTCNGAYTCNGAYGAYAGYAGY AGYAGYGAYAGYAGYAGYGGNGAYGAYGARTCNTCNTCNTCNTCNTCNTCNTCNTCNGAY CCNAGYTCNAARAAYGTNAARAARMGNTCNCARAARGARGAYAARYTNAARACNGTNGAR AGYCCNGTNGTNAARAARGARMGNAARAGYGARAGYAAYTCNAARAARGTNGAYAARAAR AGYGARAARTCNCCNAAYCARGARCCNGTNGTNAARGARAAYCAYMGNMGNCAYTCNCAR TCNAARCAYGARAARAARGAYAAYGAYGAYGARGCNMGNCCNTCNMGNAARAAYCAYGAR GAYGCNAAYCARCARAARGARAARTCNMGNAARAARAGYAARGAYGARMGNMGNMGNAGY AARAGYTGYAARAGYGTNAARATGGAYAARAARAARCAYAARTCNAGYGARGARMGNAAR MGNAGYMGNAGYAAYTCNMGNGAYGCNAARTCNGAYAARCAYMGNMGNMGNAGYMGNAGY GAYTCNMGNGAYMGNTCNMGN------------ACNAARMGNMGNMGNAGYMGNAGYGAY TCNTAYGAYAGYATHMGNAARMGNCAY------MGNMGNMGNAGYMGNAGYGTNTCNGTN GAYGAYMGNGAYCARAARTCNMGNMGNGAYTCNGTNTAYAGYGARGARGAYMGNGAYMGN MGNCAYAARMGNCAYAGYMGNGARMGNGAYGAYTTYAARMGNAGYATGAGYMGNGARGTN MGNMGNAGYMGNAGYTCNGAYMGN---------MGNAARGARTCNTCNMGNAARMGNAGY GTNAGYGCNGAYMGNGAYTAYTCNMGNCAYGAYAAYAARTCNTCNTCNTCNMGNAARGAR GAYCAYAGYAARTCNGGNMGNAARAARAARGCNGTNCAYTCNGCNGARTCNTCNGARAGY AARTCNAARTCNAARCAYMGNMGNCAYAGYTCNGARGARMGNAARGAYGGNAARACNGCN AARAGYAARMGNCAYGGNGGNMGNTCNMGNTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARTAYGTNGCNATGGAY AARTTYGARAARGTNTGYCARGARYTNTCNGGNGCNYTNMGNMGNGARCARAARGCNCAR ACNYTNYTNCARGARCARAGYAGYCARYTNGCNGARYTNACNACNMGNYTNGAYATGTGY GCNTCNGAYGGNGTNCAYAARGARCARAGYYTNGTNCARGTNCARGARGGNYTNTCNGAR ATHCARGGNCARYTNMGNCAYAARGAYCARAAYYTNMGNCARATHAGYAARCARATGACN CAYYTNCARTAYGAYMGNGAYTCNYTNGARAGYAAYYTNAARGAYGCNGARAGYGCNYTN MGNACNGCNGCNMGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CCNACNACNACN------ ------GAYCCNTTYGCNGGNGCNGAYATHTAYCAYGAYTTYCAYGARTAYTAYACNTCN GARGCNYTNAAY---CARAARTTYGAYAAYTAYTAYGTNGAYATHTCNTCNGCNACNMGN CAYMGNACNYTNTCNGARAGYCAYMGNGTNGCNGCNGCNATHTCNYTNAARTTYAGYTTY TCNTTYTAYGGNCAYCCNATHACNAGYGTNACNGTNGCNACNGGNGGNTTYYTNTAYATG AGYCCNTTYYTNCAYCARTGGYTNACNGCNACNCARTAYATHGCNCCNYTNATGGCNAAY TTYGAYCCNTCNYTNCAYGGNGGNTCNCAYATHTAYTAYYTNAGYGARGARGAYAARTTY ACNGTNGARTGGMGNGARGTNAARYTNCARGAYCARATGGGNGTNGGNAAYTTYACNTTY CARACNATHYTNCAYAGYAAYGGNAGYATHAGYTTYGTNTAYAARCAYATHCCNATHAGY ATHAGYCARATHTCNGAYAGYGAYCAYCCNGTNAARATHGGNYTNTCNGAYGCNTAYTAY AAYGAYTCNTAYATHCCNMGNTTYMGNATHTAYMGNMGNACNATHTAYGARTAYCAYGAR GTNACNGTNAARGARAGYYTNGTNMGNACNGGNTCNGTNGTNACNATHCAYCCNYTNCCN ACNTGYAAYYTNYTNTCNGAYTGYAAYTCNTGYGTNYTNCAYGARAAYGTNAARTTYGAY TGYCARTGGTGYAAYACNATHGGNMGNTGYTCNGAYGGNTTYGAYTGGTAYMGNCARCAY TGGGAYAARCARGGNTGYMGNGARACNAGYYTNAAYAARTCNGARGARTGYGTNAAYYTN AARCCNCCNAGYAARCCNATHATHGAYCCNATHACNCCNYTNGGNCCNCARGAYGARGAY TGYTCNAAYGGNAARTGYMGNAARGGNTCNGAYGCNCCNGTNGCNGTNATHGTNGTN--- GTNGTNGTNYTNATHATGTCNYTNGTNTGYGGNGTNGCNGGNTGGACNTAYTAYGCNTAY ACNCAYCCNACNTCNAARTCNGGNATGTGGYTNATGGARCAYMGNCCNAGYCARATHAAR GCNAARATHAARTTYTGGAARGARAGYAGYAGYTCNAGYGCNAARTAYAARACNGARACN GARGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GGNMGNATHMGNTAYATHGGNCAYYTN GAYAARATHGGNCARCCNAAYATGATGTTYGTNGGNYTNGARYTNGAYGCNCCNGTNGGN CAYCAYGAYGGNATHTTYAAYCAYAARMGNTAYTTYTTYTGYCARAARGAYCAYGGNATH TTYGTNCCNYTNCARGAYACNYTNTGYAARGTNGAYCCNAARAAYGARGARTGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GTNGCN TCNGTNGTNYTNMGNAGYCAYATHCARAARGARGARGARGTNAAYAARATHATHMGNAAY YTNYTNGAYTAYAAYTTYCCNGTNGARAAYAGYTTYGGNYTNATGTAYGCNTGYATHGGN MGNGGNCARCAYYTNTAYAAYAARCARAAYGTNGARTCNTCNGTNTTYMGNAARTAYTTY CCNAAYACNCCNYTNTTYGGNTTYTTYGGNAAYGGNGARATHGGNTGYACNTTY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARMGNAARGARGTNACNTCNTGGYTN TCNGARGTNTTYGGNCARGARACNGTNCCNGARTTYGARATHAAYCCNCARACNATHGAR GTNYTNTAYCAYYTNTCNACNYTNAGYCAYTAYAAYGARAARAAYGCNACNYTNTGYATH GARGAYYTNAARAARAARACNGAYGARTAYAAYGCNGAYGCNCARMGNGTNGGNGCNATH YTNMGNMGNYTNATGYTNGGNCARGGNAGYTTYTCNTCNTCNGGNGARGCNTAYYTNCAR GCNYTNGCNCARTCNGGNGCNGCNYTNGGNGTNTGYGAYGCNTCNGAYACNAGYTAYYTN YTNTGYYTNCARGAYYTNAAYGCNATHGCNAGYGARYTNTCNYTNAARYTNATHTCNCCN AGYTCNAARATHAGYAARATGTCNCARAARACNCARGAYATGYTNGTNAARMGNAAYYTN YTNGARAARACNYTNGARACNATGGARGARCARTCNCCNAARGAYGCNGCNYTNAAYCAR GARMGNAARGARGARGCNGTNYTNYTNAARAAYAARACNCARGCNAAYGARAGYAARATH GCNAARYTNCARACNGARYTNGCNAARACNGGNYTNACNGARGCNGAYTTYCAYGTNAAY YTNYTNAARAARAARGARAARYTNGAYGARYTNGARAGYACNYTNGGNCCNYTNCARTCN GARYTNCARTCNTAYGCNAGYYTNCCNCCNAAYGCNGTNGARGCNAARGTNAARATHGAR CARYTNAARCARAARYTNCAYCARYTNCARACNCARATGTCNGARTGYGTNGAYGTNGCN YTNACN------------------------------------------------------ ---------------------------------GGNAGYTGYCCNAAYCCNGGNAGYCAR GAYMGNTTYAAYYTNAAYCARTAYYTNGGNAARTGGTAYGARTAYGARMGNTTYAGYGCN TGGTTYGARYTNGCNGTNGTNTGYGGNAGYGCNGAYTAYGCNATHAAYGAYGAYGGNAGY ATHAGYGTNGTNAAYGGNGGNMGNMGNGAYATHGARGCNTTYGGNCAYACNATHATHAGY GARCCNACNTCNATHACNGGNMGNGCNACNGTNCCNGAYCARTCNMGNCCNGCNGARYTN MGNGTNTCNTTYTCNMGNTTYGAY---CCNGGNACNGGNCCNGCNAAYTAYTTYGTNGTN GARACNGAYTAYACNGGNTAYACNGTNGTNTTYTCNTGYACNGAYYTNCCNGGN---CCN TTYAGYATHCARTAYGCNTGGATHYTNACNMGNCARMGNGGNCARGCNCCNCCNAAYYTN GCNGCNATHAARGCNAAYYTNCARTCNAARGGNGTNGAYYTNAGYAARTTYAAYTCNGTN GAYCARTCNAAYTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNMGNATHMGNMGNGTNGTNGGNGGNCARCAR ATGGCNATGGGNGCNTGGCCNTGGYTNGTNTCNYTNAAYTAYGGNGARAAYCAYTCNTAY YTNGARYTNCARGGNYTNGAYCAYYTNTGYGGNGGNACNYTNATHCAYCCNGAYTGGGTN YTNACNGCNGCNCAYTGYGTNCAYTAYATGTCNGGNAGYCCNAGYYTNGGNGARCCNGAR AAYTGGGTNGCNGTNYTNGGNGARTAYAAYMGNMGNGTNGARGARMGNTCNGARCARAAR YTNCAYGTNGARGGNATHTAYGTNTAYCCNAAYTAYAGYGTNAGYCCNAAYYTNACNGGN GAYATHGCNYTNYTNAARYTNMGNCARCCNGCNCARYTNACNAGYTCNGTNMGNCCNYTN GCNATHGAYTCNYTNMGNGAYATHCCNGAYTCNTCNGARTGYAARACNGCNGGNTGGGGN CARCAYTCNCCNGAYGAYCCNGGNGARCCNCARTAYGGNAAYGGNACNATGGTNCCNCAY GTNATHAAYGTNGARAARGTNACNTTYMGNGAYTGYCAYMGNGCNTAYGGNCAYYTNTGG CCNYTNATHGAYAGYTCNGTNATHTGYTTYTAYTCNCCNCAYMGNAARGAYACNTGYAAR GGNGAYTCNGGNGGNCCNYTNGTNTGYCCNGGNACNGAYGGNGARCCNGTNYTNTCNGGN ATHGTNTCNGTNGGNATGGGNTGYGCNYTNGARAAYTAYCCNGGNATHTAYACNMGNGTN GGNAGYTAYATHAAYTGGATHYTNGCNACNATHGCNYTNCAYACNAAYATGMGNMGNMGN YTNGAYGAYCCNCARYTNYTNACNGTNGAYACNGTNYTNAAYATGYTNATHTCNTTYMGN GARGTNCARGAYTAYAARGCNATGATGAARYTNGTNGARGAYGTNAAYAARAAYACNCAR YTNAARGTNGAYTGYAAYCARGGNATHCARTAYYTNTAYGCNTTYGCNYTNAAYMGNAAY GGNAAYMGNAARGARGCNYTNGAYGTNATHCARAARGCNGTNGARAARTCNGARACNCAR GTNCCNGAYATGYTNTGYYTNTGYGGNMGNATHAAYAARGAYAARTTYGTNGAYTCNGAY TTYACNGAYCARGARGCNYTNCAYAAYGCNATHGAYTGGTAYCAYAARGGNTTYGARGTN CARCCNAAYGARTAYGCNGGNATHAAYYTNGCNACNYTNYTNGTNATHTCNGGNAARGAY TTYTCNTCNTGYGCNGARYTNCARMGNATHGGNATHACNYTNAAYAAYYTNATHGGNAAR AARGGNAGYYTNTCNTCNYTNACNAAYTAYTGGGAYGTNGCNACNTTYTTYGARATHAGY GTNYTNGCNGARGAYTAYAGYAARGCNGTNCARGCNGCNGARTGYATG------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TGYAGYMGNAARAARCCNATGMGNTTYYTNATHCARGGNYTNGAY GCNGCNGGNAARACNAGYTTYYTNTAYMGNYTNAARYTNGGNGARGTNGTNACNACNATH CCNACNATHGGNTTYAAYGTNGARAGYATH---AARATGGAYMGNTTYGARGTNGTNGGN TGGGAYYTNGGNGGNMGNGAYAARGTNMGNCCNYTNTTYMGNCAYTAYTAYCCNAAYACN GAYGGNYTNATHTTYATGATHGAYAGYAGYGAYACNGAYMGNATGGAYGAYGCNYTNGAR GARYTNAAYAGYTTYGTNYTNCARTGYGARGAYYTNGCNAAYMGNGTNGTNATGGTNYTN GCNAAYAARCARGAYYTNGAYAAYGCNATGAGYGTNAARGAYATHGARGCNAARGTNAAR GAYAARTGYAGYATHGGNTTYGGNATGTCNYTNTTYGTNTGYCCNTGYAGYGTNYTNACN GGNCAY------GGNATGACNGARGCNTTYGAYTAYTTYGTNCARACNATGAAYGAYAAR AARGCNGARAARGTNCCNGTNGGNYTNATHCCNATGATHTCNGCNAAYCARGARCCNGAR AARAAYAARGCNGAYGTNGCNGGNAARTCNCARGGNGTNTTYYTNAARGAYCCNTTYGAY TAYGTNAARTCNATHYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TAYATHACNCAYGCNMGNGTNAGYATH GTNAAYGAYTTYCCNATGATGMGNAARAARTAYYTNYTNAARTGYYTNGARGARAAYAAY TAYCAYTTYTAYCARGCNTTYAARAARATHAGYGAYMGNYTNGTNACNATHCCNATHGCN GAYMGNAARAARCAYCAYYTNTTYATGAARAARMGNMGNCAYCARGARCCNGTNCCNACN GARATHGAYGARTAYTTYTTYCAYGARTAYTGGTTYACNCAYAAYGAYYTNAARATHGAR GAYTTYCAYMGNCARAARGARYTNGTNCAYAAYYTNMGNGTNCARGARGCNMGNGARMGN GGNGARYTNTAYGARTGYGGNTGYTGYTTYGAYGAYGARTGYYTNTTYGARGAYYTNGCN AAYTGYGCNGARGGNCAYYTNTTYTGYAARACNTGYATHGTNMGNTCNACNGARGCNGCN TTYGGNGARATGAARACNMGNTTYCCNTGYYTNGCNGGNGAYTGYAAYCAYGAYATHCCN YTNAGYGTNYTNCARGARATHGTNTCNGCNAAYYTNTTYTCNAARATHATHAGYMGNATH CARGARCARGARGTNYTNCARGCNGAYATHTCNGAYYTNGTNACNTGYCCNTTYTGYCCN TTYGCNACNATHATGCCNAAYCCNGARGAYAARGTNYTNAAYTGYYTNAAYCCNGARTGY YTNAARGARTCNTGYMGNYTNTGYCARGARGARAGYCAYATHCCNYTNAARTGYAAYGAR GTNGARAGYMGNGCNGGNACNMGNATGMGNACNTAYATHGARAAYAARGTNGCNGARGCN GTNATGMGNAARTGYCAYAARTGYGGNAARMGNTTYYTNAARGAYTCNGGNTGYAAYAAR ATGACNTGYCCNTGYGGNGCNACNAGYTGYTAYTTYTGYAARGCNGARGAYATHGAYTAY AAYCAYTTYAAYAGYAAYGCNAARTGYGCNCARACNGAYCCNAAYGTNATHCAYGARMGN GAYATGAARGAYGCNGCNCAYAARGCNYTNCARGARTAYYTNTCNGARCAYCCNGAYGCN ACNGARYTNGAYYTNYTNACNTGGTGYMGNAAYGTNTCNYTNACNMGNTCNYTNMGNCAR GARGAR---------GARCARGARGCNGARGARGCNGCNAARCCNAARMGNCARGTNGTN GAYGTNGARACNAGYATHMGNTAYYTNAAYAGYAARGCNTTYGGNGCNGGNTAYGGNGAY AARCCNGTNTGGTTYCAYTAYMGNMGNAAYTTYAARGGNAARAARATGCCNCARACNMGN AARAARTGYATHMGNCARGGNGARGTNGCNACNGCNAGYCCNTGYCCNGTNTGYMGNGAY GARTAYYTNGTNGTNGAYGCNACNAAYACNAARYTNYTNGARCARTTYATHTGYCCNCAY ACNGGNGARATHTAYGAYTCNATGAARACNGGNYTNTGYAARGARCARCARMGNAARYTN ACNGTNGARGTNATGAARGCNTGGGAYCARGGNCAYYTNGARATGAARGTNCCNTTYMGN ACNTAYGAYTAYAAYGAYTAYAARAGY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MGN GCNMGNCARMGNAARYTNAGYMGNTCNAARTCNMGNCCNGGNGTNACNCARMGNAAYATH AARCARAARTTYMGNGCNYTNYTNAARAARTTYAARATHTCNGARGAYGGNYTNGTNGAY AGYGARCCNGAYCAYGAYCARATHCCNAAYCCNYTNGAYGARYTNTTYGAYGARYTNGAY GAYTCNGAYTCNGGNCCNGARYTNGAYACNATGAGYGTNATGTCNACNCCNAARCCNAAR YTNMGNCCNTTYTTYGCNAAYMGNGGNACNACNCCNGGNATHGCNGARATHCCNAARACN ATHTCNCARGARGCNTTYMGNTCNCARGARGARACNCCNGTNAAR--------------- ------------AARYTNGCNGAYTGGTCNTTYYTNGAYGGNAGYTCN---MGNGCNAAR TGYACNCARTGYAAYMGNTCNMGNAARTAYTAYTGYTAYAGYTGYTGYATHGCNYTNCCN CAYTTYGTNGAYAARYTNCCNAARGTNAARYTNCCNYTNAARGTNGAYATHATHAARCAY CCNGGNGARYTNGAYGGNAARAGYACNGCNCCNCAYGCNTCNGTNYTNGCNCCNGAYGAY GTNACNATHCAYACNTAYCCNTGYATHCCNGAYTAYTCNCAYGARAARGTNATHGTNGTN TTYCCNGGNAARGAYTCNATHTCNATHGARGCNYTNGARYTNAARGGNAARTCNGAYACN ACNAAYGCNGGNATHGAYATHCAYCCNCCNACNAARTCNGTNATHAAYGCNGAY---AGY AGYGCNACNGAYTTYATHCCNGAYGARCCNYTNAGYGAYCCNTCNMGNAARGGNAAYCAR CARYTNTGYGARAGYGAYCARAAYGARMGNATHAGYGTNAARCCNCARTAYTGYGAYGAY TGYGAYGGNCARTCNGGNTTYAARTCNCARGGNGGNTTYAAYYTNYTNGAYAARMGN--- ---AARMGNAARMGNTCNGCNAGYGARGAYGARGGNAARGARGAYCARYTNAARGAY--- ---------------CARGTNGTNATGACN---AARGAYTTYTCNYTNGARMGNGTNGTN TTYATHGAYTGYACNTGGAAYCARACNAARACNATHGTNGAYGAYGARMGNYTNAARGAY YTNACNAARGTNGARYTNCARTCNCAYYTNAGYMGNTTYTGGMGNACNCARGARGGNYTN CCNAARACNTAYYTNTCNACNATHGARGCNATHTTYTAYTTYTTYAARGARTTYCAYATG ATHTAYYTNAAYCCNYTNTAYMGNAAYGARTAYGAYAAYYTNYTNYTNTTYTTYTGYYTN ATGCAYAGYAARATHAARMGNACN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNCAYACNGAYATHTCNGCNAARGCN CAYACNGCNTAYTTYTCNATGGCNGTNATHATHYTNATHGCNYTNATHGGNGTNGTNTAY GGNACNAAYATHYTNTGGATHTTYTAYGCNYTNGTNCAYATGYTNGTNACNATGATHYTN TCNGCNCARGTNTAYTTYYTNGGNMGNTGGMGNATHGGNTGGTCNTTYTTYAARMGNTTY GTNYTNTTYYTNTTYTAYGAYYTNAARMGNTGYTCNMGNCCNGTNAGYCCNCAYMGNTTY ATHATGATGGTNATHGGNAAYATHATHAAYTGGACNTTYGCNYTNTAYGGNGCNATHGCN CARCCNTCNGAYTTYGCNTCNTAYYTNYTNGCNATHTTYATHGGNAAYYTNYTNYTNTTY TGYYTNTTYTAYGTNGTNATGAARYTNYTNAGYGGNGARMGNATHGGNYTNYTNGTNGTN GCNGTNATGYTNACNTCNYTNGTNACNTGGGGNGTNTCNYTNTAYTTYTTYTTYCAYCAY YTNACNTCNTGGCARAARACNCCNTCNGARTCNMGNGARGGNAAYMGNGARTGYATHYTN YTNGAYTTYTAYGAYGCNCAYGAYGTNTGGCAYTTYYTNTCNGCNTTYAGYYTNTTYTTY TCNTTYATGATHYTNYTNATHYTNGAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARATHAAYGCNAGYAARGARAARAARATHAARCARYTNCARGARGARYTN GAYATHYTNAAYTCNAARCCNGARGGNTCNCARGARMGNATHAARGAYYTNCARGARMGN YTNGCNGTNYTNGCNMGNGARAAYGARGARAARGAYGTNACNATHGGNMGNYTNAAYCAR GARYTNAARTCNACNATHACNMGNYTNAARGAYACNGARCAYCARYTNGCNYTNTCNGAR CARGCNMGNGCNTCNCAYTCNGARGCNCCNAARTCNAARACNTGYGCNATHATG------ ------------------------------------------------------------ ---------------------------------------------------GTNGTNGCN TCNATHATHACNCCNGAYTCNGAYGCNTTYGAYMGNCAYGAYGTNGAYTTYGTNATHAAY CARATHATGYTNGTNTCNGAYATGACNGAYMGNATHGTNGARAARGGNGGNGAYTTYGTN ------GAYGAYTCNGAYTGGTTYGCNCARGARTCNCARACNATHGGNTTYTAYYTNGGN TTYGTNAARATGGCNYTNYTNAAYYTNMGN---TCNGARAAYAGYGGNGTNGTNGTNGTN AARGARGGNATHGGNGGNATHAAYAARGGN------------------------------ ---------------------------------------ACNTTYAARAGYGAYYTNAGY YTNGAYAARYTNTAYCCNAAYTCNAAYACNGAYTTYYTNMGNAAYAAY---CAYCARCAY ACNGARGARCAYMGNAGYGARAARTTYTCNGGNTAYATHCCNATHGARCARYTNGARATH AGYTAYAGYAARAGYAGYGGNCCNGGNGGNCARAAYGTNAAYAARGTNAAYAGYAARGTN GARYTNMGNTTYCAYGTNAAYTCNGCNGCNTGGATHCCNGAYTGGATHAARCCNMGNYTN YTNGAYCARGARCARAAYMGNGTNGCNAARGAYGGNTTYYTNATHGTNAARTCNGAYATG ACNMGNAARCARATGYTNAAYCARGCNGAYTGYYTNAAYAARYTNMGNAAYATHATHTAY AARGCNTCNGTNYTNCCNGARGGNYTNTCNGARGARGAYATHAARMGNAARGARCARMGN ATHACNAARGCNAARGCNGARGTNYTNMGNGARAARAARAAYMGNTCNYTNYTNAARAAR TCNMGNTCNAARCCNGARATG--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TGGTCNYTNTGYGARGCNGTNYTNGARAARTAYGCNTAYTGYGAYAAR ATGAARATHTCNGCNAGYATHCCNAARATGCARGARYTNTTYCAYACNYTNTTYAARMGN TCNAARCAYYTNMGNTAYATHATGAGYAARGAYGCNTTYGAYAARYTNTAYTCNMGNGCN GCNGTNAAYGTNATHAARTTYTAYGAYACNACNCAYACNATGAAYCARTTYGCNGARTTY CAYGGNYTNTTYCCNYTNGCNAGYTGYTTYAAYCAYTCNTGYTTYCCNAAYGCNGARATH GARAGYGCNGARATHGGNGGNMGNCCNGGNNNNMGNATHATHGCNACNCARAAYATHAAR GARGAYGARGARATH--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TAYYTNAARACN YTNATGGARGAYTCNAGYGCNGCNGAYYTNYTNYTNTCNATHATHGAYYTNAARAAYGCN GTNATHGGNAGYAAYMGNGARAARTCNAARGTNATHGARCARGGNYTNGTNCCNMGNYTN YTNAGYTGGGTNGARGARGARTCNTGYCCNGTNGAYYTNAARACNGARTCNACNATHGTN YTNGGNAGYYTNGCNAARGGNGGNMGNGAYTCNGTNGAYGCNYTNGTNCAYGAYAARGCN GTNCCNATHYTNYTNAARGCNATGAAYACNAAYAAYYTNAARTAYAAYGARGCNATHYTN MGNTGYYTNMGNTCNATHTTYATGGARAAYACNGARGGNATHCAYTAYYTNTAYGARGAR AGYGGNTTYTCNCAYTCNTAYATHTCNACNTTYYTNGCNATGACNCARCARTCNACNGTN TGYCARGARTGYGTNACNAAYATHYTNATGTGYTGYTGYAARACNCARGARCAYCARACN TGYYTNYTNAAYAGYCARGCNYTNCCNGTNYTNTCNCCNYTNYTN---CARTCNAARCAY TAYAARATHCARATGCCNACNYTNCAYTGYTTYGCNMGNATGTGYCAYMGNAAYCAYCAR GTNTGYACNGCNATHGTNAARGAYAAYAARYTNGTNGAYACNTTYGTNGGNYTNATGAGY MGNGAYAARCCNACNGARATGCARATGGCNGCNGCNGARATGYTNACNAAYYTNCAYMGN TGYGGNGTNATHCCNGCNAGYGAYTTYGTNATHAGYMGNAARACNYTNGGNACNYTNGTN MGNATGTGYATGMGNGAYMGNACNGTNCARGARAAYGTNMGNGGNGCNGARATHYTNGCN TAYYTNGTNGARATHGAYCCNGARYTNCARGTNACNGCNAGYTAYACNTTYCAYYTNATH GGNGCNYTNACNTCNTGYYTNMGNTAYCARCAYTCNAAYAARGCNTAYTCNGTNGGNCAR AARGAYGTNGAYTGGGCNAGYGARATGMGNMGNGCNGCNTTYYTNGCNTTYGCNTCNATH AGYGCNAAYGAYAARGARATHMGNGARAARGTNATHAAYCARGARGGNATGATGGARCAY ATHYTNMGNGCNYTNTCNAGYCARCAYGARAARGARGTNGCNGCNTGYYTNMGNTGYYTN CARTCNYTNACNMGNTCNGTNCARCARATHMGNACNGTNYTNCAYGAYAARACNGTNTGG AARCCNYTNYTNGARAARGTNMGNTCNGGNAAYCARGARATHATG--------------- GTNYTNGCNATGTCNTGYYTNTGYAAYYTNGTNYTNGARTTYTCNCCNAGYAARGARGCN YTNGTNGARCAYCAYGCNGTNGARGTNYTNTGYGARYTNTGYCAYAGYGARGAYAAYATH GTNMGNYTNAAYGCNACNTGGGGNATGATGTCNATGTCNTAYTGYGCNTCNGARGARYTN MGNATHAAYATHATHAAYAARYTNGGNAARGAYACNATHGTNMGNMGNATHCARGAYCCN GTNYTNYTNATHMGNGARAARGCNYTNTGYATGGTNMGNAAYYTNYTNACNGGNAARATG AAYATHGAYCAYACNGTNAARACNYTNGGNAAYGARGTNATHGARGCNGTNTTYAARACN YTNACNCAYCCNGAYATGCCNTAYAGYATHGTNACNCARGCNYTNTGYGCNYTNAGYAAY ATGGCNGAYGGNCCNTCNTGYAARACNTAYATHATHGGNAARACNGAYGARATHACNTCN GTNATHAARTAYYTNCARTTYCARGARAARGARYTNGTNYTNCCNGCNATHCARTTYGTN AGYAAYYTNGTNGAYACNAGYGAYGAYGARTGYGGNCCNTTYCCNGGNGCNGGNTCNTAY CARMGNATGYTNCARYTNAARACNYTNGGNGCNCARACNYTNYTNGARGGNYTNATHGGN ACNGGNCARGARGARGTNGARYTNMGNGCNCARCARGCNYTNAARTAYTTYGCNATGTCN ACNTAYATHMGNMGNTAYGCNAARTAYYTNAAYGARAARGCNGTNTCNTAYMGNTCNATG GCNTTYGAYTTYTGYAARGTNAARMGNGGNAARGAYGAYGGNYTNYTNMGNACNATGAAY GCNGARAARYTNYTNAARACNYTNCCNGTNYTNCARCARCARYTNGAYGCNYTNYTNGAR TTYGAYTGYACNCCNAAYGARYTNACNAAYGGNGTNATHACNGCNTGYTTYATGYTNYTN TTYAARGAYYTNATHMGNYTNTTYGCNTGYTAYAAYGAYGGNATHATHAAYYTNYTNGAR AARTTYTTYGAYATGAAYAARAARCARTGYAARGAYGCNYTNGAYGTNTAYAARMGNTTY YTNGTNMGNATGGAYAARGTNTCNGARTTYYTNAARGTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGGCNTCNMGNACNTCNTCNGGNATHACNGCNGAYATGGAYGTN AAYYTNGAYTTYYTNACNAARGARGARAARGARGCNYTNYTNTCNAARAARATGGAYATG ATHMGNCARMGNAAYMGNYTNYTNAAYGARMGNCAYGARATGATHGARGCNGAYMGNMGN AARGCNGARGARTCNGGNAAYGCNGTNAARGCNYTNGAYAGYAARACNYTNCCNGCNGAR GGNCCNCCN------AARGCNMGNGGNMGNGGNMGNGGNCARGGNCAR------GGNNNN CARAARGARGGNAAYMGNCCNATGAARGAYMGNCCNAARTCN------GAYGCNTTYGCN TAYGARCCNATHGTNGAYGTNAGYGAYTTYAAYGGNCARMGNGGNGAYCAYAARAAYAAR GGNAARGGNGGNCAR---CAYYTNCARGAYMGN------------------GAY---AAY ACNCARTCNTCNACNCCNAARAAYMGNMGNAARCCNCARCARAARCARGARGCNGGNTTY GCNCAR------------GCNCCNGCNGCNGTNACNTTYGAYTAYGARCCNATHGTNGAY YTNAAYCARYTNGARMGNMGNTTYGGN--------------------------------- ---------------GCNMGNNNNNNNAAYNNNNNNNNNNNNNNNNNNAAYMGNMGNACN GARTCNCCNGAYAARMGN------------GGNMGNGGN------------TAYGARGGN MGNCARAARGGNGARAARAAYCCNCCNCCNGAYCCNTCNTTYAAYCCNYTNGCNGAYMGN MGNMGN---GARGGN---TTYGARAARAARGARGCNYTNAAR---AARGAYGGNGTNGAY YTNAARMGNCAYCCNMGNAAYTAYGGNGGNGGNGCNGAYYTNTCNAARGTNAARGAYACN ATGAARACNATGMGNGARAARGARMGNGAYMGNCCNGGNAAYAAYAARCCNYTNGAYATG GTNATGACNGGNMGNGARMGNAARAAYCAYGARCARTGGMGNCARGARMGNGAYMGNTAY GAYAAYGAYMGNATHCARMGNCARATHGGNGARGCNGGNAAYTGGMGNMGNGARTGGGAY ATGGAYAARATHGTNYTNGARTAYGAYGAYTCNTCNCAY------GCNMGNAARGARCCN GGNAARMGNCCN------------------------------------------------ ------------------------------ATHGGNMGNATHGGNAGYGGNMGNTTYGAY MGNGGNGAYAGYMGNGARGAYMGNCCNMGNCCNAAYAGYMGNGARGGNAARGGNGGNCCN CARCCNGGNTCNCCNAAYCAYCARTCNCCNYTNATGGCNCCNCAR---AGYCCNCCNCCN ACNATGCAR---GGNGARGGNAARCCNTCNMGNGGNAARGGNMGNGGNMGNGGNMGNGGN MGNGGNMGNGGNCCNGGNGGNGGNGGNGGNGGNCCNGGN---GAYAARTCNCCNMGNCCN MGNACNTGGTCNGGNGGNGAYGAYMGNTTYGTNGARTGYCARAARGARATGYTNYTNGTN AARTTYGAYAAYACNGCNGGNGAYAAYACNGTNGARGTNGARTAYGARAAYGGNGCNCCN ATGTCNCCNACNCCNTCNTCNAARTCNTCNGGNTCNACNCCNGGNMGNGGNCCNACNGGN MGNACNCCNAAYCARGCNAGYAAYTAYAARCCNAAYAARGGNAGYAARCCNCARAAYTCN AARCARGARAARTAYTCNAARGGNMGNATHGGNAGYGGNMGNATHTCNGGNCARTCNCAY GCN---------------GAYMGNGAYGGNGTNACNGCNAAYCAYMGNCAYTCNTAYGAR GGNTCNCARGGNMGN---------ACNTCNTCNTTYTCNCAYAGYCAYGGNGAYAGYGAR GARTGGGARGAYTGYACNGARTCNTCNGGNCAYCCNGARGAYGARGAY------YTNATG ATGGAYCCNAAYCAYTAYYTNCARYTNGAYTGYCARYTNAAYCCNGARGCNCCNGARTTY YTNCCNTCNTCNCCNGAYTTYYTNAARACNCCNCCNGGNCAYGTNAARGTNYTNAAYTGG CARGGNGCNGCNGCNAAYAAYMGNTCN------------------------TCNCCNMGN TCNAAYYTNAGYCARCAYTCNTCNCARTCNCCNMGNCARMGNAAYTCNGGNTCN------ ------AGYCAYCAYTCNTCNATHTCNTCNCCNGGNTCNTCNGCNTCNACNAARGCNMGN AARMGNMGNGARGARGTNGAYGCNATGCCNGARCCNGAYGCNCCNATGCCNCCNCCNTTY YTNYTNCARGGNCARGGN---------YTNTCNGCNGCNCARGAYAARYTNAARAAYGGN GAYGTNAAYCAYGCNGAYGAYGARCAYGARGARGARGARGARGARGARGAYGARAARTTY GARGAYTCNATHGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------GCNACN TTYAAYAARATGGAYGCNATHMGNYTNCARCARGARCARYTNGCNAARGARCAYTTYGAR YTNGAYYTNYTNCCNMGNACNGGNTCNAAYMGNYTNAAYGCNGARGARTCNMGNAARGAR AGYAGYGARAARATGGAYAARYTNATHGGNCAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNAARGTNGTNACNYTNGTNGCNCAR GCNCCNCCNGCNACNAARGCNACNACNGCNCAYYTNAAYGGNGTNAARAAYTTYAARAGY TTYAARAARACNGCNCAYMGNGGNAGYAGYGAYYTNCCNACNATHATHGGNGGNTGYGAY YTNCARCCNCAYAARGGNGCNAARYTNATHCAYATGGARGAYYTNATGGARGCNGCNGCN GCNGAYCARAAYGGNGTNGARGARGAYGARYTNTTYGGNTGG------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CCNCAYGGNGCNAGYCCNACNGAY ATGAGYCAYCCNCAYACNGGNCARCCNMGNCCNYTNMGNTAYGGNAAYGAYAAYAGYAGY GTNAAYMGNCARTCNMGNACNCARAGYACNMGNCCNGAYCCNATHCCNGGNCARCCNTAY GCNGGNGCNCCNGCNCARMGNGTNGGNAGYGCNCCNYTNMGNAARATGGGNAAYCARCAY ------GCNGCNMGNATHAAYGCNGGNATHGGNAGYMGNTCNAGYYTN------------ ---------------GARCCN--------------------------------------- GGNGAYACNAGYGAYAGYCCNAGY------------------CCNTTY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AAYYTNGCNYTNGGNYTNAAYATGGGNGCN MGNCCNTAYAAYGCNGCNCCNGGNGCNGARGCNGCNAARTTYMGNAAYCCNAGYYTNGTN TCNCCNGCNAAYGGNYTNYTNGGNAAYGCNTTYTTYCARAAYMGNACNATHGCNCCNMGN AGYGCNAGYATGTCNAARGARGTNACN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGAGYACN TCNGTNGGNACNATGMGNGCNGGNTCNAAYAARCCNYTNGGNCCNAARGAYAARCARGCN AARGGNGAYAARAAYACNTCNTCNCARCARACNCCNYTNACNAARATHGARAAYCAYTCN AAYAARATGCARCCNACNCARGARCARYTNMGNTTYGCNGARATGATGAAYACNAAYCAR ACNGAYGCNGAYCCNAAYACNGTNAARCARYTNATGGARATGACNGGNAARAGYGARGAY GTNGTNGTNATHGCNYTNCAYGAYGCNGGNAAYGAYGTNGARMGNGCNGCNATGATGYTN YTNGARGGNGGNGARGARCARGGNGARTGGYTNGARCARGGNGGNAARAARAARAARAAR ---AAYACNCARAARGARACNTCNAAY------GGNGARGAYCCNACNGAYAAYMGNGCN AARGARAARACN------------ACNGARAARGGNGGNGAYACNCARGARATHCCNCCN MGNMGNGGNMGNMGNAAYGGNGGNCCNCCNCCNMGNYTNGCNMGNGGNMGNGGNMGNGAR AARGGNAAYTTYGGNGAYMGNGAYAARGARMGNAAY---AAYGCNGCNGARGAYTGGGAY AAYGARAARGARGAYMGNGGNTCNGCNGCNMGNAAYGAYMGNGAYMGNAGYGGNGCNGAY MGNGGNMGNTCNMGNGGNMGNGGNGGNTTYGGNGCNMGNAARCCNGCNAAY--------- GGNCCNGTNGGNGGNMGNTTYAAYAAYAGYAAYGAYMGNGARAAYMGNGGNTTYACNMGN CCNMGNMGNTTYGARAARATHAGYAGYGCNCARCCNYTNGAYGGN------CCNGARATH GAYACNTGGACNAAYGARACNGCNGCNAGYAAYGTNACNAAYAARGAYACNGAYTGGAAY MGNTGGAAYGAYTCNTGGGTNAAYGARGARGAYCARTGGACNGGNACNYTNGARGARACN ACNGTNTTYACNCCNTCNCAYGTNAARATGCCNGARCCNGAYCCNGTNAGYAGYGARCCN CCNAGYTCNYTNGGNCARMGNYTNGAYGTNGGNAGYYTNTTYGARAAYGCNAARTTYACN AARGCNCCNGAYTAYAGYAARCCNAGYGGNGAYTCNTAYATHACNCARTTYAAYCARGCN GCNACNGARTCNATHAARAAYACNATHGGNATHGGNAGYTCNCCNMGN------------ ---CARCARATGGGNYTNTCNGCNCARAAYTCNTCNAGYTCNYTNGGNYTNACNAAYYTN GGNCARAAYTCN---------------CARGGNAGYYTNTCNCCNYTNCARCARTCNAGY TCNCARAAY------TCNYTNCCNCAYGCNATGGCNCARYTNTCNCARATHCARCAR--- ---------------------------------------------CCNGCNTCNCARTCN GTNACNATGTCNCAR---------ATHGGNATHGGNTCNCARTCNATHCARTCNAAYAGY AGYCARGCNCCNCARCARTCNMGNATHCCNGCNGTNATH------------------CAR CARCARCARAAYYTNCCNCARGCNAAYATG---AAYAAYATGCARCARMGNCCNAARCCN CARMGNTCNAARYTNCCNCCNCCNTCNAARATHCCNTCNACNGCNGTNGARATGCCNGGN CAYATHCCNMGNAAYCCNCARYTNGAYGTNCARTTYGGNYTNGAYTTYGGNTCNGARCCN TCNGTNCARTTYGGNTTY---GGNAGYGGNGAYAGYACNCARGGNTCNAGYTCNTAYTCN GCNACNTCNAAYGGN---ACNACNGTNATHACNAAYCAYYTNAAYCARGGNCAYGTNAGY CARTCNGCNGGNGAYGGNAAY---GTNCCNACNATHATHCCNTCNCCNTCNGTNGGNTCN AGYAARGTNCCNCCNGGNATHGARACNCAYGTNTCNAAYMGN---CARGGNGTNTTYCAY AAYGCNGTNTAYTCNTCNTCNCARCCNAARAAYGARGGNCARACNATHGARMGNGAYCAR ACNAARGTNAAYGARACNATHCCNTTYYTNTCNTCNCARYTNGARMGNAARTCNAGYCCN ATG------GGNCARCAYTCNGTNCARACNAAYCARAAYYTNAGYTCNGGNACNATHACN TCNAGYAARAAYGAYTCNTCNAAYGCNGCNGCNAAYAGYAGYTAYTCNGCNGCNAAYGGN TAY---TCNTCNTCNTAYCARGGNCAYTCNAARGGNTCN---------ATHTCNCAYACN GCNATHTCNCARTCNGCNCAR---AAYTCNTTYCCNGGNCARTAYCCNGGN------CAR TCNTAYTCNTCNTCNGGNCARACNCARTTYCCNGCNCCNTCNAAYAAYGCNTCNTTYCCN CCNTCNGCNCAR---TAYAAYTCN---------AAYTCN------TCNCARAAYCARTAY TCNTCNGGNCARAGYCARTTYTCNGCNGGNACNTCNACN---------YTNGTNCAYCAR GGNCARTAYCCNCARAGYGGNCARACNAGYTAYGGNAAY---GGNCCNTCNCARTAYTCN GCNTAYCARAAYTCNAGYTCNTTYCCNTCNCAYCCNCARTCNCARAGYAAYTAYCCNTCN AAYCARACNGGNGGNAGYGGNACNGCNYTNTAYCCNTCNACNACNCARTCNGGNGTNCCN YTNTAYACNTCNCARTCNAAYTCNTAYCARTCNCCNTCNTCNGGNTCNTAYCAYTCNTCN MGNGAYGGNCCNACNAAYATGACNGTNTCNACNCARTCNTCNAGYAGYYTNCCNTTYTCN AGYCARAAYCARAGYTCNAGYATGAARCCNGTNGTNACNCARAGYAGYTCNTCNTTYAAY TCNCARAGYTAY---TCNAAYCARGCNCCNYTNCARTCNCARTCNYTNGCNAAYAARYTN GGNGARGGNYTNTCNAARATHTCNATGAARGAYTCNTCNGCNGTNYTNGAYAGYCAYCAR GCNTCNCARTAYGAYCAYACNCCNTCNGCNGCNAAYGTNCCNACNAAYGTNAGYYTNCCN TCNGGNTCNAGYTCNGCNTCNYTNTCNACNGGNACNAAYACNATHTCNTCNACNTCNGCN GTNACNTCNGTNTCNTCNGCNTCNMGNGTNGCNTCNATGCCNTCNACNTCNGGNAARGCN CCNCCNAAYYTNCCNCCNGGNGTNCCNYTNATGGGNCARTAYATHATGGGNCARAGYACN ATHCCNCCNTTYTAYAGYGTNCARCCNCCNYTNTAYGGNTAYGARGAYGTNCARYTNYTN CARCARMGNATGCCNATGCARTCNGGNAGYTTYTAYGAYATGAGYGCNTTYCCN---GCN CCNGCNGGNTCNACNYTNCCNGCNGGNMGNGAYCARCARCCNCCNATHCCNAGYGTNCCN TTYTCNGGNACNTCNGAYACNAARYTNAAYMGNGTNGAYGCNCARAGYCCNAAYGCNTCN AGYCARCCNCARAGYGCNCAYTCNGCNGCNCARCARCCNYTNTTYAAYTTYCAYTAYGGN TAYTAYTAYCCNTCNATGTTYCCNGGNGCNGCNGGNYTNCARTAYCCNACNACNGTNTAY CCNATHCCNCCNGTNACNAAYGCNGCNGCNCAYCCNGGNACNACNTCNACNACNCARTTY CARAARTCNTAYCCNTCNCAYGTNTAYACNACNAARGGN--------------------- ------------------------------------------------------------ ---------------TCNGGNACNAAYGARATHACNCCNAAYGCNTAYAGYAARTCNCAY GGNCAR---GGNTTYGAYAARCARGGNTAYCAYGGNGGNACNCCNCCNCCNTTYAAYYTN CCNYTNGCNACNGCNACNCARACNGGNCCNATGGGNGCNCCNACNACNCCNTAYGGNGCN CCNTTYYTNCCNGTNATGGCNGCNCAYCARCCNCAYTCNCARATGATGCAYCAYCCNATH CARCARGAYTCNAAYAGYAGYAGYTCNMGNGGNYTNAAYCCNGCNGCNGGNCARAGYAAR TCNGGNACNGCNAARTCNTTYGGNGGN---CCNCCNTTYTGGAAY---CCNACNGCNATH TCNTAYYTNCCNGTNCCNCARYTNTGGGGNTTYATHTTYTTYYTNATGYTNTTYTCNYTN GGNYTNGAYACNCARTTYACNAGYGTNGARACNYTNYTNACNACNGTNATGGAYYTNTAY GCNTGGATGGTNMGNTGGMGNAARAGYGTNAGYGTNGTNACNATGGTN---ATGYTNACN YTNTCNTCNTTYATHTTYGCNACNMGNGGNGGNATHTAYYTNTTYACNYTNGTNGAYTGG TAYATHGCNGCNTTYTCNATGATGTCNCARGTNGCNYTNCARTGYATHGTNGTNGGNTGG ATHTAYGGNGCNGAYMGNTTYTGYGCNGAYATHGARYTNATGYTNGGNMGNAARCCNTAY MGNGTNTTYGTNGTNTTYTGGAARTTYATHTGYCCNGCNGTNYTNGTNATHGTNYTNGCN GTNACNYTNGCNTTYTTYAARGCNGCNAARTAYGGNTCNTAYGARTTYTCNCAYACNGCN CARGTNTTYGCNTGGATHTTYTCNGTNGTNCCNTTYTGYTCNATHYTNYTNGTNGCNGCN ATGGARYTNYTNAARCAYAARGGNCCNYTNGTNGARMGNYTNAARAGYGCNTGYMGNCCN AGYCAYGARTGGGGNCCNGCNYTNCCNCAYATHMGNGARAARTAYATGGGNGTNYTNGAY ATGYTNAAYCCNGCNYTNYTNYTNAARYTNMGNYTNGGNGTNTAYGGNGTNYTNATHTTY TTYGCNTTYTTYATHTTYGTNGGNGTNGCNGTNATGMGNGAYAARTTYGTNTTYGAYGGN TGYCCNYTNTAYGCNGAYACNAARGGN------------AGYGGNCCNGAYTCNAAYTGY AAYTAYCCNATGGCNATHTCNATHATGTAYCARYTNYTNTAYYTNYTNTTYMGNATHGGN ACNYTNGTNYTNGTNYTNATHGGNAARTTYACNGCNGAYATGGTNYTNTTYTCNGAYYTN GCNGARTTYGTNTAYGTNGTNGTNGAYYTNTCNGCNTTYTTYYTNATHTTYATHGCNGCN TGYATHYTNTCNGCNGGNACNAAYGAYATGTGYGAYACNTTYAAYTGYAGYCAYAAYGAR TTYGARGAYACNTAYTCNGCNTCNAARGCNGCNCARGCNGGNGCNTGGATHAGYACNTTY YTNTGGYTNTTYATHGGNATHTGYGGNTTYYTNATGYTNTGGMGNGCNGGNAARATHCCN TTYYTNCARAGYGGNGGNTCNGCNAARTCNGARTCNAAYACNGGN---GCNGAYCARAGY CARCCNCCNATHGARGGNCCNCCNTAYAAYCCNGAYGARCCNCCNAARTAYATHGTNTAY TGYAGYCCNAGYGGNGTNYTNYTNACNTCNCAYGARGARATHMGNGARTAYYTNYTNAGY CARGAYACNTGYAARTGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGAYTCNACN YTNAARTGYMGNATHMGNMGNMGNYTNTAYCAY--------------------------- GGNGAYGARGCNAGYYTNCAYTCNCCNTCNYTNCCNTTYACNGARGARGCNGTNCARTAY TTYMGNAAYAGYTTYCCNGGNGARGARGGNYTNGGNMGNYTNGAYATGCCNACNGCNTCN TCNATHATHATHAARAAYAARGTNTCNCCNTGYTCNATGGTNATGTCNYTNYTNTAYGCN AARMGNYTNMGNCARMGNAAYCARCARTAYYTNCARTCNATGTCNTCNACNGAYGTNTTY TTYATHTCNATGATGATGGCNAGYAARTAYYTNTAYGAYGARGGNGTNGARGAYGARGTN TAYAAYGAYGARTGGGCNGGNACNATGGGNCAYGAYGTNGARGAYGTNAAYCARATGGAR ATGGAYTTYYTNAARGARATGGAYTGGCAYYTNTTYGTNAARMGNGARGARTTYGAYTCN GCNYTNACNGCNATHGARMGNMGNYTNGCNATGAARGARGGNATGAARMGNGGNTGGTTY TCNTAYACNGARYTNTCNGTNYTNYTNGAYTGGGAYCCNGTNTAYGAYTGGTGGCARCAR GTNGGNGTNGAYTGYACNAARGTNGTNTCNATHYTNTCNACNGTNTAYGTNGCNAGYYTN GTNAGYATGATGGGNTCNGCNGCNATHGCNYTNCARYTNTCNGGNCCNATGGCNACNGCN ACNGTNGCNYTNYTNTCNATGCARTGGGCN---------------------------AGY MGNMGNTGYTGYCCNMGNTCNGTNAAYTAYGGNTGYACNTCNACNMGNMGNAAYATGCCN TGYTTYTAYAGYTAYCARGGNGGNGCNYTNCARTGGTGYTGYCCNATGTGGCCN------ CCNATHAAYTAYGCNCARTGYACNTGYAGYCARTGYGCNGTNYTNACNCCNTGGTGYGCN AAYGARGGNMGNTGYCARMGNMGNTAYGTNMGNMGNTCNTTYCARGCNGTNTGY---TTY MGNAAYAARCAYTGGGCNTAYYTNMGNTGG---ATHACNMGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGTNTGYGTN CCNTGYTTYGTNATHCCNGTNATHYTNTGGGTNTTYCAYAARTTYATHMGNCCNTGGYTN TCNAARATHTGGAGYGGNTCNGAR---TAYGTNACNAGYAAYYTNACNTGYCCNATGCCN CARAARAARAARAARATHCARAAR------------------------------------ ---------------ATGTCNAAYGCNGGNTTYTTYMGNGGNACNACNGCNCARCARGAY ACNMGNTTYTCNGAYAARAARAARAARYTNATGAARACNATGAARTTYGGNGAYGTNYTN GARAARAARGTNGAYATGACNAARGTNAAYGTNGAYAGYYTNAARCCNTGGATHGCNCAR MGNATHACNGAYYTNYTNGGNATHGARGAYGAYGTNATHGTNGARTTYGTNTAYAAYCAR YTNGARGAYMGNCAYCCNGAYGGNAARGARATGCARATHAAYYTNACNGGNTTYYTNAAY GGNAARAAYGCNMGNGTNTTYGTNGCNGARYTNTGGGARCAYYTNTGYAGYGCNCARGAR AAYATHACNGGNATHCCNAAYCARTTYYTNGARCARAARAARAAYGARATHAARCARMGN CARGARGARCARGARMGNYTNCARGARCARYTNAARAARAARGARGARCARATHAARGAR CARYTNTCNMGNGARMGNMGNGARYTNGARAARAAR------------------GAYATG AAYAAYYTNTCNCCNGAYMGNCCNAARAAYAAYGARGARAGYAAYGGNATHAARCCNGTN ATHCAYMGNGGNATHGGNGTNGCNGGN------YTNAGYGCNGTNGARGTNAARCCNGAR CCNAARGARGTNGCNGAR------------ACNCCNGTNGARAARCARCCNCCNACNGAR CCNGARAARGARTCN------AARGARAARGARMGNGARAARACNCCNGARAARAARAAR GAYCAYMGNGAYAARGAYMGNMGNMGNCAYTCNMGNAGYCCNGAYMGNCAYMGNCAY--- MGNTCNMGNACNCCNGAYMGN---CAYMGNMGNGAYCAYMGNGAYMGNGAYMGNTAYGAY MGNGGNMGNTAYTCNCCN---------------------------CCNMGNMGN---MGN TCNCCNMGNMGNMGNACNCCNCCNCCNCCNMGNMGNMGNTCNCCNGCNCCNMGNTCNTCN CCNTCNMGNAAR------------------------------MGNTCNCCNAARAARGCN GARAARMGNGAYGARMGNTCNAGYAGYGGNAGYAGYTCNAGYGAYTCNGAYGCNAAYTCN GAYAARGARGAY------------------------TCNTCNCCNGAYAARGGNGGNATH CARCARMGNMGNAAYTAYMGNAARCAY---GARGAYAGYGGNAARGAYTCNTCNTCNGAY TCNTCNGGN---GAYGARCAYGAYMGNAARMGNCCNCCNCCNCARTCN------MGNGAY MGNMGN------------ATGATGMGNMGNACNCCNTCNCCNTTY---MGNGCN------ ---MGNMGNACNCCNCCNAARMGNMGNCCNAGYCCNCCNMGNMGNMGNTAYCARTCNCCN CCNMGNMGNMGNATGAGYCCNGTN---CAYMGNMGNAGYCCNTCNCCNMGNMGNMGNTCN CCNCCNMGNCAYTCNCCNATHMGNMGNMGNAGYCCNCCNCCNCCNCCNMGNMGNMGNATG TCNGTNTCNCCNMGNMGNMGNMGNTCNTCNGGNCCNMGNMGNCARATGTCNCCNGCNCCN MGN---GGN---MGNMGNCCNCCNTCNMGNTCNCCNTCNGGNTCNCCNGTNAARMGNMGN MGNCCNTCNCCNCCNCCNAARTCNCCNCCNGCNMGNTCNAARAARCARAARTCNCCNCCN CCNTCNGARTCNGARGAYAGYTCNAGYTCNGGNGARTCNTCNCARTCNCCNCCNCCNCCN CARACNAARMGNCCNCCNACNAARGGNAARGAYGGNAARCARAGYCARGCNCCN------ CCNGCNCAYAARACNCARCCNGCN---------------------AGYAAYAGYTCNTCN TCNGGNTCNGARGAYAGYGARGARGAYTCNGAYTCNGARAARGARTCNCCNCCN------ ------AARAARTGGMGNGARGCNACNCCNCCNMGNCAYGTNAARGCNCCNAARCAR--- ------------CARMGNYTNYTNCCNGAYGCNMGNMGNAARTCNCCNMGNMGNTCNAAR ---------------------TCNMGNTCNMGNTCNCCN---GTNAAYMGNMGNGAYAAY AARTCNAGYCCNCCNCCNGCNMGNMGNMGNGCNGAYTCNMGNTCNCCNCCNCCN------ ------------AARAARGTNTCNMGNGARGAYCCNTCNGCNAAYACNGAYTCNGARCCN GARTCNGGNMGNMGNGAYMGNMGNCCNMGNGARGARTCNAGYCCNGGNMGNAARMGNCCN GCNCCNGCNTCNCCNMGNMGNGAYCARGARGARTCNMGNMGNGAYMGNYTNCCN------ ---------------TCNCCNCCNMGNATGAARCARMGNGARCCNGARAARAARMGNATG ATHATHMGNAARGARGCN------------------------TCNCCNTCNGARAGYAGY AGYGGNGARAGYAGYTCNGARGARGAYMGNCARGTNAARGGNAARGGNAARGCNGARGGN MGN---------------------------CARGGNGAYAARCCNTCNCCNGCNGCNAAR MGNMGNMGNTCNCCNTCNGCNAGYCCNCCNCCNCAYGAY--------------------- ------------------------------------GCNGTNAARCAYTCNMGN------ ---MGNGAYGGNMGNGAR---------------GAYGAYCAYTCNMGNGGN------GAR AARGGNMGNMGNMGNCCNGCNAGYCCNCAYMGNGARGAYAARACNMGNGARGARGARCCN TCNMGNAAYGGNAARGTNTCNGCN---------------------------GCNCCNCCN CCNAARGCNYTNAARAARGAYMGNCARGAYYTNTCNGCNAGYAAYAGYGARTCNGARGGN TCN---GAYTCNGAYGAY---GCNTCNAARAARAARAARAARAARAARGAYAARAARCAY AARAARCAYAARAARCAYAARAARCAYAARCAYAARAARGARGTNCCN---------GAR MGNGGNGARGAYYTNGARCARMGNYTNMGNGARAARGCNYTNCARTCNATG------CAY AARAARGTNAGYCARGTNTCNCARGGNAARGAYTCNGGNGAYTCNGGNAGYAGYAGYGGN GAYGAR------------------------------------------------------ ---------------------GGNMGNCARATGGGNTTYYTNGAYYTNMGNGGNGCNGCN TAYCCNYTNTTYGCNAAYMGNAARTTYMGNMGNGAYAGYTTYGTNTCNTGGGAYCCNAAY CAYGTNCARAARCCNGAYGAYYTNGTNAAYYTNGGNTTYTTYTAYGCNGGNTAYTCNGAY TGYGCNMGNTGYTTYTAYTGYGGNYTNGGNYTNAARTAYTGGMGNCCNACNGAYGAYGCN GCNTAYCARCAYGCNMGNTTYMGNCCNYTNTGYYTNTAYAAYAGYTTYGTNAARGGNCAR GAYTTYGTNGAYGARGTNCARMGN------AGYATHGCNCARGAYCARCARAAYGCNTCN GARGTNGTNCCNAAYYTNGAYGARYTNATGMGNTCNGAYGCNGCNGCNCARGTNATHGGN GAYGGNTGGTCNMGNGAYCARGTNCARGARGGNYTNGTNAARYTNGTNCARGAYYTNGGN GARGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARTTYTGGMGNAAYAARGARMGNGTNAARGCN CCNTTYGAYATHAGYAARTGYTGGGAYYTNMGNCARMGNAARYTNYTNGAYGTNMGNTAY GAYAGYMGNCARAAYGTNTTYGAYTGGGAYTAYAGYATGGARYTNACNGARMGNGGNGGN TCNATHGTNCAYTCNAARCARTAYAARTGYTGGMGNGARGAYGGNATHGCNTTYACNATH MGNGARGGNACNTAYGAYGTNCCNAAYMGNACNYTNTCNTCNGCNATGGTNTTYAARCAR GAYGGNGARMGNTAYCCNMGNMGNGGNTAYTGG--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TAYCAYGGN ATHAAYAAYTAYACNCCNACNMGNTCNCAYACNGGNATGCARCAYGGN------------ ------------------------------GGNGAYCARCCNTAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GGN YTNCCNYTNAAYGARACNYTNATGTCNCARCAYYTNAAYGAYYTNGGNTAYMGNTCN--- ---------CAYATH--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ GTNGGNAARTGGCAYYTNGGNATG------------GTNAARTGG---GARTAYACNCCN YTNTAYMGN------GGNTTYGARTCNCAYYTNGGNTAYTAYCARGGNTGYGARGAYTAY TAYGAYCAYACNTAYGARGCNAAYCARGCNCAR--------------------------- TGGGGNYTNGAYTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TTYGCNGTNACN MGNCCNMGNGGNGTNTCNYTNGARAARGCNTCNTTYTAYCARGCNGAYMGNGAYTTYMGN TGYYTNTCNGAYGGNAARGTNATHCCNTGGACNTAYGTNAAYGAYGAYTAYTGYGAYTGY GCNGAYGGNTCNGAYGARCCNGGNACNTCNGCNTGYCCNCARGGNGTNTTYTTYTGYGAR AAYAARCARTTYAARGGNACNTAYATHAARTCNTCNMGNGTNGAYGAYGGNGTNTGYGAY TGYTGYGAYGGNTCNGAYGARACNGAYGGNACNGTNGAYTGYGARAAYACNTGYATHGCN CAYTAYAARAARGARATGGCNCARCARGARGCNGTNMGNMGNACNCARGARGARGGNTAY AARGTNAARCARGARTAYATGCARCARGGNAARMGNGCNAARGAYGARAARYTNGCNAAR YTNAGYGARGTNGARMGNGARAAYGARATHYTNAARAGYGARAARGARACNGCNGARGCN GCNAARAAYGCNGCNGARGARCCNGARACNATHGCNAARGARGARCAYAARAARGCNTGG GARAARGTNAARGARGARYTNCARAARGCNAARGAYGCNGCNGCNGCNYTNAARGCNTTY ACNGTNYTNGAYGTNAAYCARGAYGGNATHGTNGAYTAYCCNGARATHATGAAYMGNAAR GARTTYGAYATHGAYTCNGAYGGNACNGTNAGYGARGARGARTCNAARGARTAYYTNGAR GAYAAYGARAARGTNGAYGTNGCNACNTTYACNGARAARATHTGGCCNAAYATHAARGAR ATHTTYAAR---GTNGARGARYTNGARTCNCCNCCNCCNCCNGARGGNGAYGARGARTCN AGYAGYCAYGAYGARGAR---------------------------GGN---GAYACNAAY CCNTCNACNCCNTCN--------------------------------------------- ---------------GARGARACNGARCCNGARTAYAGYGARGARACNAARAAYYTNATH GCNGCNGCNGAYGARGTNMGNACNAARTTYGAYGARGCNGARMGNAARYTNMGNGAYAGY GARMGNGARATHAGYGAYATHAARAARTAYATGGARATHGAYTTYGGNCCNAAYGARGAR TTYGCNACNYTNAARGGNAARTGYTTYGARTAYACNGAYMGNGARTAYACNTAYACNYTN TGYCCNTTYGAYMGNACNTCNCARAARAAYAARAAYGGNGGNATGGARACNTCNYTNGGN ACNTGGGGNAARTGGAAYGGNCCNGAYGAYTCNAARCAYGARGCNATGAARTAYGARAAY GGNCARGGNTGYTGGAAYGGNCCNACNMGNTCNACNGTNGTNAAYYTNCAYTGYGGNCCN ACNAAYGARGTNACNMGNGCNTCNGARCCNAGYMGNTGYGARTAYATGTTYGARTTYACN ACNCCNGCNAARTGYAGYGARCCNAARGCNCARYTN---AARGAYGTNCAYGARGARYTN YTNATGGTNACNGARCARCCNYTNCAYTGYACNGTNATGCCNCCNGGNACNGCNYTNTTY CAYTTYAARATHGARGAYGAYACNAAYGTNGAYTAYCARTGGATGMGNAAYGGNAARGAR GTNACNGAYGAYGCNMGNGTNTCNGGNTCNAAYACNAAYGARYTNAARATHTAYAAYATH GARAAYGARGAYTGGACNGGNTGYTAYTAYTGYMGNATHTCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TGGAGYTTYGARTTYTCNGTN YTNATGGCNACNATHYTNTCNATHTCNTCNTTYGTNACNATHGTNGGNAAYGCNATGGTN YTNACNGTNATHTTYMGNCAYMGNGGNATGMGNACNMGNACNAAYYTNTTYYTNGTNAAY YTNGCNATHGCNGAYYTNYTNGTNGGNGTNATGGTNGTNCCNTTYTCNATHACNACNYTN ATHGARGGNMGNTGGGTNTTYACNGGNTTYATGTGYGCNYTNAAYGGNTGGYTNAAYGCN YTNTGYYTNATHACNTCNATHCAYACNYTNATGTAYATHGGNATHAAYAARTAYTGYTCN ATHGTNCAYCCNYTNAGYAAYCCNATHAARYTNTGGCAYATHGTNACNATGATGYTNGCN GCNTGGATHTGGGCNGCNGTNTGYGCNACNYTNACNGTNACNGGNYTNAAYAAYGTNATH TAYAARCCNGGNACNTCNCARTGYGGNCCNGCNTAYCCNAARGARYTNAARGGNTAYYTN TTYCAYGGNYTNATHCARATHACNTGYACNTGGATHCCNTTYTGYATHYTNYTNTTYTGY TAYATHCARATGTTYMGNGARATHAARMGNCAYTCNGARMGNYTNMGNAAYAAYACNACN GTNCARGARGAYTAYATHYTNACNCARCARAARAARGTNGCNGTNACNYTNTTYATHGTN YTNGCNTGYTTYATHYTNATGAAYACNCCNTAYYTNTTYTAYGCNAGYTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARCCNTCNTTYGAR AAYGGNCARYTNTCNTAYYTNGGNTAYGAYGTNGARMGNATHCCNAAYAARYTNATHGAR GAYTAYTGYAAYATHTCNTCNMGNYTNGAYYTNAGYTTYAAYMGNYTNAARTCNYTNAAR GGNYTNGARCAYTTYAARTTYYTNAARGARYTNGTNYTNGAYAAYAAYGARYTNGAYGAY TCNACNCARTTYCCNCCNYTNMGNGARYTNCARACNYTNACNATHAAYAARAAYAARYTN ACNGAYYTNACNMGNYTNATHGARCARTTYCARMGNAARTAYCCNCAYYTNACNTAYYTN AGYYTNYTNGGNAAYCARGCNTGYCCNAAYCARYTNTCNTCNAAYGAYAARGAYGAYGAR GAYTAYCARMGNTAYMGNTAYTTYGTNYTNTAYAARYTNCARAARYTNMGNTTYYTNGAY TCNTCNCCNGTNACNTCNAARGARATGGCNGARGCNAARMGNGTNGGNCCNTTYATGCAR GTNGTNMGNCCNGCNGARGAY------GTNGGNGARGARGARGARGTNTCNTCNYTNAGY GAYTCNAARTAYACNCCNYTNCCNTCNAAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYAARCARGARGAYGAR ACNTTYATHAARATGTTYAARYTNACNGAYATHATHTTYATHAGYACNGGNYTNTAYGAR CARACNYTNAAYATHGARAGYMGNGAYAARAGYAARCARAARCARMGNYTNTGG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AGYAARMGNAARACNGGN ATHATGAARAARGCNTAYGARYTNTCNACNYTNACNGGNACNCARGTNATGYTNYTNGTN GCNAGYGARACNGGNCAYGTNTAYACNTTYGCNACNMGNAARYTNCARCCNATGATHACN AGYGAYAGYGGNAARGCNYTNATHCARACNTGYYTNAAYTCNCCNGAYCCNCCNCCNGGN ---ACNCARTCNGGNAAYTCNCCNGARCAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNAAYAAYGTNMGNTCNGTNATHGARYTN TTYTGYACNATHYTNGCNGAYCAYGGNATHTCNGAYYTNMGNGCNGARACNYTNMGNCAR GGNAARTTYAAYMGNGAYYTNATHACNAARMGNATGTGGGARGTNYTNTAYGAYGTNGTN TGYTTYYTNGAYAARAARTCNGCNACNATHTCNGTNAARCARAARYTNCARAAYTGGGGN TAYYTNTCNAARGCNTTYGCNGARYTNCCNATGAAYGGNACNTAYGGNAGYMGNGARATH YTNYTNTCNYTNGGNTGGYTNATHMGNAARMGNCAYYTNTTYAAYGARATHATHMGNMGN MGNAARAGYCCNYTNCAYCARAAYATHYTNCAYTTYACNTGYMGNATHCCNGAYAAYGCN TCNYTNAGYCCNGCNCAYMGNCCNMGNGAYYTNCCNTCNCARGARAARATHCARCARCAR GTNATGYTNTGYGGNAARYTNAARYTNAARYTNMGNMGNYTNTTYGCNGCNCAYCARGAR YTNGCNAARYTNCAYTGYAARATHCARAGYTGYACNAAYGGNGTNAGYGTNCARACNGAY ATHAAYCAYYTNACNGCNYTNGARGTNYTNYTNYTNMGNTAYGCNGARAARYTNTCNACN ATGATHCAYACNYTNGARGARGAYAAYGCNAARYTNAARMGNYTNYTNGAYTGGAAYGGN AARGARCARGTNTTYTGGGAYTGGATGAAYAGYGTNYTNACNYTNCAYATHGARGARTGY GARAGYGAYCAYMGNCARGARTCN---CARGAYGARGARTCNGTNTTYYTNGAYGTNCCN GTNGAYATHGGNGAYCARATHTCNAGYYTNMGNGCNYTNATHMGNGAYTTYATHYTNGGN CAYGARGAYGAYTTYGAYAARYTNGARAARYTNGGNACNAAYAARAARATHTCNAARYTN GAYYTNGARYTNGCNAAYCAYGCNGTNCARAARGARYTNTTYGARYTNTCNCARGARTTY TCNMGNTAYTCNGTNGGNCAYTTYGAYGTNCARGGNCARTCNACN---ACNGARGGNGAR TCNYTNTGYGAYAARATHGAYAAYGARYTNTGYGCNGGNYTNGCNMGNMGNCARCARMGN TAYGTNCCNCARACNGCNCARACNGTNAARGCNTCNAARGARGCNGARYTNTCNCAYYTN ATHAARAARGARATHTGYGCNYTNCARGCNGARGTNGARAAYYTNAARMGNGARYTNAAR CARGCNCARGTNAAYAARYTNGAYGCNYTNCARAAYTTYACNGARAARGAYCCNAAYTCN ATHTGYATHYTNCCNMGNTGYTTYAARCAYGTNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATHGAYMGNCCNCAYGGNMGNCARGARMGNCAYMGN CARACNGTNGGNCCNCAYMGNMGNAAYTTYCCNCCNGAYAARACNCCNCCNTCNCAYMGN MGN--------------------------------------------------------- ------------------------------------------------------------ ---------------------------ATGTGGACNCCNGAYGAYGCNGGNGTNGTNTTY TGYGCNTGGTAYCAYGARCCNTAYMGNYTNGGNYTNAARCAYTGYTGYCARMGNAARAGY GGNYTNTAYCAYYTNGAYATHCARAARGGNTCNGTNGARYTNYTNAGYGARGARGGNMGN GCNGTNMGNTTYCCNMGNTTYAGYCCNAGYATGAGYMGNYTNATHTAYTTYGAYACNCCN GTNGGNGGNGCNCAYYTNCARTGYGCNMGNATGGTNATGATHGAYTGGGCNACNATGAAR AARMGNATHATHGTNGAYACNGTNMGNCAYGCNCCNGCNTCNGARTTYCARGGNATHTTY ATHGCNACNYTNCCNMGNAAYGTNTGGTTYGARGAYAGYATHCAYATHGCNYTNTCNACN GCNTGGMGNAGYYTNACNMGNGTNGTNGTNATHAAYACNGAYAAYGGNACNGTNCARCCN YTNCCNTCNGARTCNAAYCARAARTGYATGTCNYTNYTNTAYGTNGARAARACNAGYYTN YTNATGTCNGCNTCNTCNYTNTCNACNCCNTTYCAYYTNGTNGTNGCNCAYYTNCARGAY GTNTCNAAYGTNGAYTCNGTNMGNTGGYTNCAYCCNGAYGGNACNCCNGARTCNYTNGAY TGGGTNTCNTCNTGGGARGTNYTNCARCAYGCNCCNACNTCNGAYMGNGTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGGGNGAR---MGNGARCAYGTNGARGCNTTYGTNACNYTNGCN ACNAAYGAYACNTAYTCNYTNGGNTGYYTNGTNYTNGCNAAYTCNYTNMGNMGNGTNGGN ACNACNMGNCARYTNGTNGTNATGATHACNGGNGGNGTNTCNCARCCNATGMGNCARCAR YTNGARACNATHTTYAAYMGNGTNGTNGTNGTNAAYGTNYTNGAYAGYGCNGAYTCNTGG AAYYTNAAYYTNYTNGGNMGNCCNGAYYTNAGYGTNACNTTYACNAARYTNCAYTGYTGG MGNYTNACNCARTAYAAYAARTGYGTNTTYATGGAYGCNGAYACNYTNGTNYTNAARAAY GTNGAYGAYYTNTTYGAYMGNGARGARYTNTCNGCNGCNCCNGAYGCNGGNTGGCCNGAY TGYTTYAAYTCNGGNGTNTTYGTNTTYAARCCNTCNGAYGTNACNTAYACNAAYYTNYTN CARTTYGCNGTNTCNCARGGNTCNTTYGAYGGNGGNGAYCARGGNYTNYTNAAYYTNTAY TTYAAYACNTGGGCNACNGCNGAYATHAGYMGNCAYYTNCCNTTYACNTAYAAYGTNGTN TCNCARGCNTTYTAYAGYTAYYTNCCNGCNTTYCARCARTTYAARGAYCARATHAARATH GTNCAYTTYATHGGNGCNGTNAARCCNTGGCAYCAYCCNTAYAAYATGAAYTCNGGNATH GTNACNGCNYTNTCNGGNACNGGNCAYAAYCARGGNTTYYTNCARGTNTGGTGGGAYATH TTYATGGAYAARGTNCARCCNCAYGTNGAYAARGGNYTN--------------------- ------------GCNTAYTCNYTNYTNGGNTCNAAYCCNCAYMGNTGGGCNMGNCARMGN YTNTGGGGNAGYYTNGGNATHGGNYTNTCNATHGCNACNACNGCNGTNGGNATHCAYGGN AGYGAYYTNTCNACNATGTGYTAYGTNAGYYTNATHYTNTGYYTNGCNGCNYTNGTNGCN ATHTTYAARYTNGAYGTNAARAGYGAYAARAARAGYTCNAGYYTNACNCAYGAYYTNMGN ACNGTNYTNGCNAGYTCNCCNTTYMGNYTNYTNYTNTGYAARYTNGTNTTYTTYGGNTTY ATGACNGGNACNGCNCARAAYTTYTTYATGTGGTTYATHGCNGAYATHGGNGGNTCNMGN YTNAAYYTNGCNATGACNGTNATHATGCAYTGYACNTCNTCNATHGTNYTNYTNTGGGTN ACNGGNMGNYTNYTNAARMGNATHGGNCCNYTNTGYGCNATHTAYYTNGTNTCNGCNGCN TAYGTNGTNMGNTTYTTYAGYGTNTCNTTYYTNMGNTCNCCNTGGGCNGCNYTNCCNYTN GARYTNYTNCAYGGNGTNACNTAYTCNATHTTYTGGGCNGCNACNTCNGGNTCNATHAGY CARGTNGCNCCNCAYGGNACNCARGCNACNTGYCARGGNATHGCNGGNGCNGTNTAYTGG GAYYTNGGNMGNGGNYTNGGNACNATGACNACNGGNCARYTNATHCARGTNATHGGNGCN MGNTGGACNTTYMGNGCNTAYGCNGGNGCNTGYGCNGTN--------------------- ------------CARTCNGCNACNGAYAGYATGAARYTNYTNGCNAARAAYAARACNGAY GAYCARAARACNGTNGTNTCNCCNACNAAYGTNATHYTNTCNGCNAAYGAYGAYGGNGTN ---------------GARGAYAARGGNYTNAAYGAYAGYAARTAYATHTAYCARGGNGAY YTNAGYACNGTNCCNGAYAAYAAYAAR------------------AAYGAYGAYAAYCCN ATHYTNTCNMGNATGAARGAYATGGTNATHGARAARACNMGNTCNTCNTCNCARAARGGN AAYAARAAYAAYTTYYTNGAYAAYTCNATHTCNTCNYTNAAYAAYGARGARAGYAARCAR AAYTCNGAYCCNATHYTNGCNAARACNGAYGCNTCNATHGAYATGGGNATHGAYGGNGTN GTNATGGCNGCNACNTCNCCNCCNGCNGAYGAYGTNTCNACNCAYGGNGCNTCNGAYYTN GTNGAYGCNACNGARGAYATHGAYCAYGCNGGNAARMGNATHACNGAYTCNGCNTTYGAR TTYYTNGAYACNTAYYTNTCNGAYGAYGAYGGN---GARGGNCCNGTNGAYAGYCCNCCN ATHTCNCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNACNCCNCCNTTYTCNGGNGGNAGYACNCCNCARAGYCARTCNMGNGCNCCNTCNCCN GCNTGGAGYGARAGYAGYGGNAAYATGAGYACNAGYAGYGTNTCNGGNGCNTCN---TCN TAYTCNMGNAARTGYCARGGNACNGCNCCNGTNCCNMGNCAYAARMGNCCNTCNCAYMGN MGNGCNGARGTNAARMGNMGNGAYAARATHAARACNTGYYTNGAYGAYATHAARGGNCAR GTNCCNTCNYTNCARGAYAARGGNAARYTNAGYGARTCNGCNATHYTNYTNAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ACNCAYTCNTTY YTNAGYACNTCNTCNYTNTGYATHGTNGCNAGYGTNATHGTNYTNGTNATHGGNTTYYTN GGNGTNATHMGNTCNGARYTNGTNGGNGGNATHMGNTAYGAYTAYMGNACNGARGTNCAR GTN------------------------------------------------CAYGCNGGN TTYATHGGNGTNCARGAYYTNGARYTNTGYCAYYTNCCNGGNGTNYTNCARMGNTCNGAY ATHYTNGAYTAYATHAARGCNGARGCNAAYYTNACNGTNMGNYTNAARGTNAARTTYACN AGYYTNAAYMGNCCNGAYACNGAYGCNTGYGCNAARCAYMGNGGNAGYMGNTTYGCNMGN ACNGCNTCNGGNYTNTCNYTNYTNGAYAAYCCN---GAYTGYTTYAARTCNAARYTNTGY ACNGTNCCNAAYTGYCAYMGNAAYMGNCCNGARCAYTCNATHTTYGARGGNGAYYTNAAR ATHTTYACNAAYAARCAYGTNATHTTYGAYGARGARGARYTNGCNAARACNACNGTNGAY TTYTTYTAYAGYGAYGAYAARAARGGNATGGTNCARGARTAYGCNACNAARYTNTTYTAY YTNAAYGGNGCNTCNGAYAARGCNTTYATHAARGTNACNATHCAYGAYCARGAYATGTTY AARMGNATGYTNGAYGGNGAYMGNGCNGAYMGNTTYCCNAARACNGTNYTNGAYAAYTGG AGYCCNTAYGCNATHYTNATHTCNCAYCCNCAYGGNATGCCNAARAARATH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYGGNGTNMGNYTNMGNGCNMGNGCNTCNTCNMGN CAYAARTCNCCNTCNCCNGCNTCNGAYAARGAYTCNGCNATHGGNTCNCAYAARTCNTCN CCNYTNTCNMGNMGNATHGTNGAYGTNGARGCNAARACNGARAARTGYTCNCARCARCCN AAYCCNCAYYTNATGMGNCAYGARMGNCCNTTYYTNGARAAYAGYATGGAYGARGAYCAR TGYTCNGAYYTNTCNCAYACNGCNCAYAGYATHGAYTCNGGNGGNGARGTNTTYGARGAY GARGARGARGGNGARGARGGNGAYGAYGAYYTNCCN------CCNCAYYTNAAYCARTCN YTNTCNGAYATHCARTTYMGNCARTCNYTNATGCARMGNATHCARGARTGGTCNGAYYTN GCNCARGARTAYAAYAARTCNCAYACNCCNACNCCNGARTCNTCNCCNYTNMGNATGGTN MGNMGNAGYMGNTCNYTNGAYMGNCAYATHGGNGAYGCNTCNATHYTNGCNGTNGAYCCN GARYTNCCNCCNTCNCARCCNATH---GTNGARCCNGTNACNGARMGNAAYYTNGARACN YTNGARTTYGARYTNCAYGAYATHCARGGNGARTTYGARTCNATHACNTCNACNYTNCAY AAYYTNATHCAYCARGGNGAYATHTCNCAYGCNTCNATGTCNTCNTCNGCNGCNYTNGCN CCNMGNCCNTCNCCNCCNCCNCAYAGYMGNATHCARCCNCCNTCNTCNTCNGCNCARGGN TCNTCNTCNCCNTCNCAY------------CCNGCNCARAGYACNTCNMGNAARACNCCN GAYTCNTCNTCNAAYYTNMGNAARATGAARACNAARTGGGARAARGTNCCNGGNTAYGCN TAYTCNGAYTCNAGYMGNAGYTCNMGNGGNAGYAGYGTNGARTTYGTNTGGGAYYTNGCN GAYTAYGCNAAYGCNAGYMGNTCNGGNAGYAARYTNYTNTGYACNACNGAYYTNTGYCCN GTNGAYGCNTCNGAYTGY---GTNGTNAAYATHGGNAGYCCNGTNTCNGTNTCNGARTAY TGYAGYAARGARTGGATGGGNGAYACNCCNAARGCNCAYGCNGTNMGNCARGGNTAYGAY TCNGTNTCNGCNYTNCAYGGNTGYCARMGNYTNTGYGTNATHMGNGGNGAYAAYTAYTGY GGNYTNMGNGGNACNYTNTTYCARGTNYTNTGYGCNGGNCAYMGNGTNGCNGCNCAYTGG ---GGNATHATHAGYATHGTNGAYMGNYTNCAYAGYYTNTGGGAYAGYCCNACNGCNCAR YTNCAYACNTGGTCNTTYGCNGGNMGNYTNCAYTCNCARACNAARGAYAARYTNGCNACN YTNTCNAARTGYGCNYTNGCNYTNTAYGCNACNGTNGARGARGTNTGYAAYYTNCCNACN GGNCARGARMGNGARAARMGNACNCARAGYYTNYTNAAYACNAGYGGNACNTTYGAYGTN GARYTNATGGARGGNYTNAARGTNATGATGGCNYTNGTNYTNGTNGAYYTNCARCARMGN TGGCARGAYGGNGGNGAYGTNCCNYTNTTYYTNCAYYTNYTNTTYGCNMGNGAYACNTCN CARACNGTNCCNGAYTTYATHMGNAAYCAYYTNAAYCARATHGGNGAYACNGGNGGNATG GARCARGTNGARATGTGYYTNYTNGGNTAYACNYTNGGNGTNTCNATHAARGTNYTNMGN YTNAGYCARAGYGGNCARGARGAYTTYGARTGYTGYTTYCCNGARGAYATGTTYGARGAY ACNCCNGARATHYTNYTNGTNGCNGARGAYGAYMGNCAYTAYAAYGTNCCNYTNCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNAAYGTNTCNTAYAARTCNGGNGTNAAR GAYYTNMGNTTYYTNGAYTCNAGYYTNTTYCCNAGYGAYYTNCCNGARTAYCCNCCNTAY CCNGTNTCNTCNGCNACNTTYATHYTNGCNGARTGYTTYGAYGGNACNCARGCNYTNTAY GAYACNTGYGAYGGNAGYCARCARATHCCNMGNTCNATHGCNTCNGTNCCNGARAAYGAY GAYGAYGTNCARACNYTNYTNMGNATHATHCCNGARYTNCCNGAYYTNATGYTNTAYGTN AARAARAAYGGNTGYATGTAYATHAARGAYATHGGNAGYGGNGCNACNYTNTGYCARGTN TAYATGCCNGCNCCNCAYGCNATHCARACNCCNTGGAAYCCNATHTTYGCNTTYGGNAGY GGNGGNMGNGTNYTNTAYYTNAARGCNGARGGNACNGAYACNAGYGARGARGGNGARGTN AGYGAYATHTCNTGYYTNATGAARTTYAAYYTNMGNGARTTYTCNATHYTNGARGARTAY TGGGCNMGNCARMGNGTNAARTCNGAYYTNATHGTNTAYACNACNTGYCARGARMGNYTN GAYGCNYTNATGAARGARMGNYTNCARCARCARGCNYTNMGNAARCCNMGNATGCARACN CAYTGGGGNCARYTNMGNGGNGARYTNGAYATHATHCARAAYGCNMGNGARATHCCNGTN GAYACNYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNCCNGCNTAYGCNACNCCNCCNGCNTTYCCN CAYMGNGTNGGNYTNGARTCNAGYTCNACNGGNTCNTCNTTYCCNGCNGAYTTYACNAAR CCNGTNCCNYTNGCNGTNGTNTGGCCNGAYGGNMGNAAYCCNGGNACNCARACNTCNAGY CCNTGGGGNAARTCN---------GCNCCNGTNCCNTGYTCNYTNGARGAYGTNATGAGY GARCARYTNGCNACNAARYTNCAR------------AARGARGARGAYGAYCARGTNYTN GAYAAYYTNAARTCNAGYGARGCNGGNGCNGGNCCNATHTCNGARCCNGCNGAYMGNGAR YTNACNGAYGCNGARYTNGCNGCNAARYTNGCNGCNGARGARYTNGGNTTYGAYCCNAAY GAYGARGCNATHGCNGTNATGYTNCARAARCARTTYGAYMGNGARTAYGAYGCNGAYYTN TCNAARMGNGARCARAARTAYAAYGGNAAYAAYAARGTNTCNATHTCNTTYGARAAYTAY AARMGNAARCAYCARCARTAYCARAAYGCNGAYGAYGAYGARGAYGAYGAYGAYGAYTTY TAYGARGAYGARAARCCNGAYTAYCCNYTNCCNACNAARTGGGARAAYTCNACNCCNACN ATHGGNAGYAARGGNTAYAGYGGNCAYGGNAARAAYATHGTNACNAARCAYGAYAARGTN ATHTGYGGNMGNMGNAAYGCNGARMGNYTNATGGARTTYCCNCCNGAYTTYGGNTGYGGN GAYGGNGARGGNATGGAYATGCARYTNCCNAAYAARGTNTAYAAYAARYTNAARMGNCAY TCNCARTCNGARAAYAARAARAGYAAYAARGTNCAYGARAARAARGAYCAYTCNACNGCN ATHAARGCNGTNGAYGARAARACNMGNATHYTNATHTTYAARATGATHAAYTCNGGNTTY YTNTCNTCNGTNGAYGGNGTNGTNAGYGARGGNAARGARGCNGTNGTNTTYAARGCNGGN GGNGGNGARAARGARGGNGTNCARYTNCCNMGNGAYATHATHYTNAARGTNTAYAARACN TCNATGAAYGARTTYAARACNMGNYTNAARTAYATHYTNGGNGAYTAYMGNYTNTCNAAR GAYGTNYTNAARMGNTAYAAYCCNMGNAARYTNATGMGNATGTGGGCNGARAARGARTTY YTNAAYYTNAARAARYTNCARMGNAAYGGNGTNCCNTGYCCNTCNGCNYTNACNYTNAAR AARCAYGTNYTNGCNATGAGYTGYGTNGGNGGNGCNACNCCNGCNCCNAARYTNMGNGAY ATHCCNYTNAGYTCNGCNGAYYTNGARGAYGCNTAYCARCARAGYGTNGARYTNYTNAAR ACNATHTAYCAYAARTGYAAYATGGTNCAYGCNGAYTTYAGYCCNTAYAAYYTNYTNTGG CAYGAYGGNAARGTNTGGGTNATHGAYGTNGGNCARGCNGTNGAYMGNGARAAYGCNAAY TCNACNTCNTTYYTNYTNMGNGAYTGYAARAAYATHTGYGAYTTYTTYMGNCAYGGNGGN GTNTAYAAYGTNCCNTCNGCNGARACNYTNTTYAAYCARATHACNCAYTTYTCNATHCAR GGNGARGGNAARGTNTTYGARTCNCARGTNCARMGNTAYGARAARGAYGAYTAYGCNTTY GAYTAYTTYTTYGAYYTNACNTCNTCNGCNMGNYTNCARAARYTNGAYATHAAYAGYGAY AGYGAYGAYGAYGAYGAYAGYGARGARGARGAYGGNGAYGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CARAARGAYMGNGAYACNCAYAARAARGGNGTNTGGGCNCAYTCNCARATHATGACN CAYCCNAGYTCNCCNCCNGTNCARCCNYTNMGNMGNGAYGCNGCNCCNCCNTCNCCNCAY CCN---GAYGCNAARCCNGTNCCNCARCCNAARAAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TGGMGNAARGGNAARACNMGNGAYGCNGTNMGNGAYGAR TGGCCNAARTCNAARAARTCNTGYMGNTAYGTNMGNTTYGTNYTNTAYAARGARAAYAAR GAYACNATGGAYGCNATHGGNYTNATHGCNAARAAYYTNAARGTNMGNGARAGYATGTTY CARTAYGCNGGNACNAARGAYAARMGNGCNAARACNTCNCARGARATHACNGCNCAYMGN GTNCAYCCNAARAARYTNGTNAAYYTNAAYAARGTNYTNTGGAAYATGGGNYTNGGNCAY TTYMGNTAYGTNCARCARCCNYTNAARYTNGGNCARYTNTCNGGNAAYMGNTTYACNATH GCNYTNMGNAAYGTNCARAARGGNCARGARGTNGTNGAYTCNGCNYTNACNTCNYTNAAR GTNAARGGNTTYATHAAYTAYTTYGGNATGCARMGNTTYGGNACNACNTCNATHCCNACN CAYAGYATHGGNMGNGCNYTNYTNCARGGNGAYTGGGAYMGNGCNGTNGAYYTNATHYTN TCNCCNMGNAAYGAYGTNCCNGCNAARGAYAARTTYCARAARATGTGGGCNGARACNAAR AAYCCNAARGCNACNYTNGAYGTNACNCCNMGNTAYTGYGGNYTNGARMGNAAYATHYTN GARGCNYTNGCNAARAARTGYAARCCNTTYAAYGCNYTNGARAARYTNTCNMGNAAYACN MGNYTNYTNTAYGTNCAYAGYTAYCARTCNYTNGTNTGGAAYAARATGGCNTCNMGNMGN YTNGCNGARYTNGGNCAYTGYGTNGTNCCNGGNGAYYTNGTNATG--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGAAY CCNAGYMGNTCNYTNGGNTCNGCNGTNGCNTCNGARTCNTGGGAYGAYCAYTGGATHTAY TGGGTNGCNCCNATHGCNGGNGGNGTNYTNGCNGCNATHGTNTAYAARTTYGTNYTNAGY CCNTAYMGNGGNGTNGTNAAYATGGAYGARGCNYTNGAYAARATGAAYGGNGAYCARAGY ATGYTNGTNGTNCCNAARGARTAYTTYAARATGGAYACNAARACNACNGAYACNCAYATG ATHTTYAAYCCNCCNAARGGNATHYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR GARGARGARGARGARGARAGYGTNAGYGTNTCNACNGTNCARAGYTTYTGGGARGCNATG GARMGNYTNGTNYTNGARAGYAARGCNYTNTCNYTNGGNATHTGYGAYYTNGGNAARGAR CAYYTNGARGCNYTNTAYAAYTGGGCNCARGTNAARCCNTGYGTNAAYCARGTNAAYYTN GARTCNTGYTGYGTNYTNCCNAARGAYYTNACNGARTAYGCNAARGCNATHAAYGTNCAR YTNYTNACNCAYAAYGAYAAYCCNGCNTTYYTNACNAARGARYTNYTNCARGARAARATH CARAGYGTNTCNACNGAYGARGAYGGNAAYGAYTGGTCNCCNGAYTGGGTNGCNMGNTAY TCNGGNYTNYTNAARTGYMGNGGNATHATHMGNYTNAARGGNTAYYTNYTNCAYGCNACN MGN---AAYAARGARCARATH---GTNAAYTGYCCNYTNTAYGAYCARYTNMGNATHMGN CARYTNMGNYTNTTYGARYTNGTNATHAGYCARTCNCAYCARATGYTNYTNATHCAYAAR CCNGTNATHAARCCNYTNYTNAARYTNYTNATGGARGTNGCNGARTCNCARGARATHAAY AAYGGNGARYTNGARTTYAARYTNGTNYTNGTNYTNCAYCARATHTGYATHTGYATHTCN CARCARGGNYTNATHYTNGARAGYTTYTTYAGYACNGAYACNGAYCAYGGNCCNGCNMGN TTYYTNATHTTYTCNYTNYTNATHCCNTTYATHCAYMGNGARGGNCCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AAYGGNGCNTCNGAYAARMGNAARAARMGNMGNAGYMGN TGGAAYACNGAYAAYGAYGAYAARACNGTNATHCCNGGNATGCCNACNGTNATHCCNAGY AAYYTNTCNGARGCNCARCARMGNCARTAYGTNGTNCARYTNCARATHGARGAYATHACN MGNAARYTNMGNACNGGNGARYTNGGNATHCCNTCNGTNCCNGARCARNNNTCNCCNTCN CCNGARCCNATHTAYAAYAAYGARGGNAARMGNYTNAAYACNMGNGARTAYMGNACNMGN AARAARYTNGARGARGARMGNCAYMGNYTNATHCARGARGCNATGAARYTNAAYACNGAY TTYAARCCNCCNAGYGAYTAYAARCCNCCNGTNATHMGNGTNAAYGAYAARGTNATGATH CCNCARGARGARCAYCCNGAYATHAAYTTYGTNGGNYTNYTNATHGGNCCNMGNGGNAAY ACNYTNAARACNYTNGARAARGAYACNGGNGCNAARATHATHATHMGNGGNAARGGNTCN GTNAARGAYGGNAARATHGGNMGNAARGAYGGNCARCCNYTNCCNGGNGARGAYGARCCN YTNCAYGCNTAYGTNACNGCNAAYCAYCCNGARAAYGTNAARAARGCNGTNGARAARATH AARGARATHATHAARCARGGNATHGARGTNCCNGARGGNCARAAYGAYYTNMGNMGNCAR CARYTNMGNGARYTNGCNYTNYTNAAYGGNACNYTNMGNGARAAYGAYGGNYTNCARAAR YTNMGNCARATHGCNGARAGYCARACNATHGTNACNAAYACNATHGTNTGYACNGTNTGY GGNGGNACNGGNCAYATHGCNCARGAYTGYAARCARAARMGNCCNGGNGAYACNTTYMGN ATGCARCARATGCARAAYCCNGCNGARMGNGCNAARATGGAYAGYGARTAYATGTCNYTN ATGGCNGARYTNGGNGARGGNCCNCCNCCNCCNAARTCNGARGGNGGN------CCNAAY ---------------AAYCARCCNTAYAAYGCNMGNCCNYTNYTNACNAGYCCNCCNCCN AAYCCNATGGCNATHAAYTCNCCNTGGCARATGCCNCCN---AAYMGNCCNCCNATGGCN AGYCCNGTNCCNCCNCCNCCNAGYTCNGGNCCNGCNCCNYTNYTNAGYMGNCCNCCNACN GGNATGCARACNTCNTCNCCNCARATHAAYCCNATGGGNMGNYTNCCNATGCCNYTNATG TCNACNCCNGTNCARCCNCCNCCNGGNATGCARGGNCCNCCNGGNATGYTNCCN---CCN GGNCARCARATGGGNGGNCCNATGGCNCARCARCARCARCARCARCCNCCN--------- ---------------CARCCNAAYCCNCAYCARCARCCNCCN------ATGMGNCCNTGG CARCARCARCCNGGNACNCARGCNCARCCNATGATGAAY--------------------- ---ATGTCNCARGGNGCNGCNTCNAAYGCNGGNATGGGNGTNCCNCCNCCNCCNCCNGGN ATGATGGGNGGNCCNCCNCCNCCNCCNGCNAAYAGY---------CARGGNCAR---CAR GCNCCNCCNCCNTGGATGCARCARCARCARCARCAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNGARATGGAYGARAAYGAYAAYAGYTTYCCNTGGGGNYTNATHCAY CAYAGYGARYTNGCNAAYATGYTNACNAGYGGNYTNGGNAARACNGTNGTNATHGAYAGY MGNTCNTTYYTNGARTAYAAYACNAGYAAYATHCARCARTCNGTNAAYGTNTGYTGYTCN AARYTNGTNAARMGNMGNYTNCARCARGAYAARGTNCAYATHATHGAYYTNYTNAAYCAR ACNTGYAAYGTNGTNGCNGAYTCNAGYTGYGAYGTNATHGTNTAYGAYCARTGYACNGAR GAYCCNTCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNCCNYTNGCNMGNGGN---CARCARTAYAAYATHYTN TGGAGYCAYAGYATHTAYAAYMGNTCNGCNTTYMGNCARTTYATGCCNAAYTCNACNGCN TAYATHTCNATHYTNMGNGARCCNTTYCARCARTTYGTNTCNTCNTTYGARTAYTAYGGN TTYTCNAARGCNATGGCNAARYTNAAYATHAGYTTYCAYCCNATGGCNAAYCCNATHTCN ACNTTYYTNMGNTAYCCNATGTTYATHMGNCAYGGNCCNYTNCARTAYGGNTAYATHMGN AAYAARCARGCNCARGAYYTNGGNTTYGGNMGNGARGARTTYTAYCAYMGNGAYMGNYTN GARTCNAGYGTNMGNCARYTNGAYAARGAYTTYACNAGYATHATGATHATGGARCAYTTY GAYGARTCNYTNYTNYTNYTNMGNCAYAARYTNTGYTGGGCNATHAARGAYATHYTNTAY ATHCCNAARAAYAARAAYAARCAYAARCCNAAYMGN---------------------MGN AAYGTNAARGARATGATHGGNGGNTGYTGYGTNTGYTCNGAYGARYTNGGNTGGAGYGAR AAYCCNYTNGTNTAYTGYGAYGGNCARGGNTGYAAYGTNGCNGTNCAYCARGCNTGYTAY GGNATHGTNCARGTNCCNACNGGNCCNTGGTTYTGYAARAARTGYGARTCNCARGARMGN ATHGCNMGNGTNAARTGYGARYTNTGYCCNCARMGNGAYGGNGCNYTNAARMGNACNAAY TCNGGNGGNTGGTGYCAYGTNGTNTGYGCNYTNTAYATHCCNGARGCNTGGTTYGCNAAY GTNCARACN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATGCCNGGNGGNMGNMGNATHYTNTCNMGNATHCARTCN AAYAGYCCNTAYTCNTCNACNGGNAARAAYTCNAGYGGNGGNGGNAGYCAYGGNCCNGAR GAYMGNGAYGGNAAYATGGTNCCNYTNGCNTCNATGGTNGTNYTNCCNAARCAYAGYCAR YTNCCNGAYATHCCNGGNGAYGGNAAYYTNTAYTTYGARTGYATGYTNTTYGTNTTYGGN ATHATHATGATGTGYYTNCARTAYATHAAYYTNTAYAARACNGTNTGGTGGYTNCCNCAR TCNCAYGCNCARTAYGCNYTNAAYTTYTAYYTNATHGAYTTYAAYYTNGCNGTNYTNATH TGYGTNATHYTNGCNGTNMGNTTYYTNATHTGYTTYTGYCARGARGTNCAYAAYAGYAAR ATGYTNTAYTGGCCNYTNTTYATHYTNAARACNATHATGGTNAGYTTYGCNGTNATHGTN YTNGTNTAYACNGGNTAYAARGTNATHATGGARCAYGGNGTNGTNACNAGYYTNTTYYTN TGYTAYCCNGCNGTNATHTAYCCNYTNYTNTTYGGNYTNGCNATHAARCCNYTNTAYCAR MGNCAYCARGCNTGGCCNMGNCCNGCNTAYGGNATHGAYMGNTCNGCNGGNCCNACNMGN ATHAARATGAARGAYGAYGCNCCNYTNTGYCAYACNTGYACNYTNACNCCNGAYATHGTN MGNGARGARGTNGAYATHYTNAARMGNGAYTTYAAYAGYMGNYTNAARCARATHYTNTTY AAYTCNYTNACNACNTCNTTYTAYGCNACNGGNGTNCCNGTNTGGTTYTCNCAR---AAY ACNYTNTAYTAYGAYTCNTGGTGGATGTGGCARCAYGTNTCNYTNACNTGGYTNAGYGCN YTNYTNATGYTNACNGCNCAYTTYYTNCCNCCNCAYTAYYTNCAYYTNYTNCAYAARAGY GCNMGNCAYYTNGGNMGNTGGCARMGNATGGARGCNMGNCAYGCNCAYGTNCCNTAYAAY GCNTGGTCNGARYTNCARGTNTGGCCNCARGGNGCNYTNGTNAARCAYGTNMGNGGNYTN TTYAARGCNGARGGNATHAAYGTNACNGCNGARCCNGGNAAYAGYYTNCAYAGYMGNTTY TTYYTNYTNTTYCAYCARCCNATGMGNGTNATGAAYTGGYTNGTNTTYYTNACNTGYYTN GTNATGGCNTAYCARGCNTTYAARYTNGTNCARAGYTCNGARTGGAGYCAYATHATHTCN YTNGCNYTNYTNATGTTYTGYAAYTTYTAYACNYTNTTYAARYTNATGMGNGAYTGGTTY ATHATGGGNAARATHTAYAARGAYCAYGAYTAYGTNGTNTCNAAYTCNGAYGAYGCNGAR GAYGARTTYGTNGAYGCNATHGARAAYAARCAYCCNTCNYTNCARAAYGGNGGNCCNCCN AAYTCNCARAGYGTNYTNMGNGAYYTNGAYGGNAARATHAARGCNGGNGGNATGGARMGN YTNAAYCAYTGYYTNAAYCARYTNYTNGARATGTCNAAYTCNMGNCCNAARAAYGCNGAR ATHTTYTGGMGNYTNTCNGARACNGARTAYYTNYTNGCNGAYGARGARYTNGCNYTNGGN MGNCCNCARTCNAARGCNMGNCAYGAYGARYTNATGTCNCARGCNAARAARGCNGCNGAY AARGCNATHAGYYTNAAYCCNAAYTCNGGNTAYGCNAAYAARTGGATGGCNATHATHYTN GGNAGYATHACNCARYTNATGCCNGTNCARGAYCARATHAARAAYGCNTTYGAYATHAAR GAYCAYATHGAYAARGCNYTNTAYTAYYTNCCNCARGAYGCNYTNYTNCAYCAYGTNATG GGNMGNTGGTGYTAYTCNGTNTAYATGATGACNTGGGTNGARMGNAARYTNGCNTCNGTN YTNTTYGCNACNCCNCCNACNGCNACNYTNGGNGARGCNATHCARGCNYTNYTNMGNGCN GARAGYYTNGAYCCNYTNTCNTCNGTNTCNAAYGARYTNTTYYTNGCNAARGCNTAYATH GCNAARGGNGARTAYAARATHGCNGTNAARTAYATGAARGAYGGNGARAAYYTNAARTGY CAYTCNACNCAYGAYCARAARGCNYTNGARGARATHMGNAAYYTNYTNCARCARTAYAAR TCNTAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CCNCCNYTNAARTCNCCN AAYCCNAARCCNGTN------GAYGARCCNTCNGAYGTNTAYGAYGAYGGNTGYTCN--- YTNTCNGGNYTNYTNYTNTAYGAYTGGTTYCAYGGNGCNATHGAYMGNGAYGARGGNAAY AARMGNGTNGGNTCNATGAAYACNGTNGGNGCNTTYYTNATHMGNGCNAGYACNCARAAR CCNGGNGARAARTAYCCNTAYACNYTNGTNGTNAARACNGARAARGARGTNAARAAYYTN MGNGTNMGNYTNMGN---CARGAYGGNGARTAYGCNATHGGNAARGAYAARCCNGAYGAR ATHCAYTTYTCNTCNYTNATHGAYYTNGTNYTNCAYCAYMGNGARAAYGAYGTN------ ---------------------------CCNGGNCCNGCNGAYTGGGAYAAYGGNACNTTY TCNAAYTAYCARCAYMGNYTNTCNATGCCNYTNACNGARTGGCCNATGACNTCNACNAAR ATGTGGTAYAGYYTNGAYYTNGGNCCNGTNCAYYTNATHAGYTAYTCNACNGARGCNYTN GCNTCNGAYGGNGTNAAYGCNCCNMGNCARCAYAAYTGGYTNYTNGAYGAYYTNGARGTN GCNAAYGCNAAYMGNCAYMGNACNCCNTGGATHGTNGCNTTYGGNCAYMGNCCNATGTAY TGYTCNGTNACNGAYCCNGCNYTNTCNTGYAAYAARAARGTNTCNAARACNGCNAARGAR YTNGARGAYTTYATGTAYCAYTAYGGNGTNGAYYTNGTNATHTCNTCNATGGGNCARGGN TAYGARATHTCNTAYCCNATGTAYAARMGNGTNAARGTNGGNGAYACNTAYGTNGAYCCN YTNGCNCCNGTNCAYGTNACNGTNGGNTCNGCNACNCCNTGGAGYGCNAAYTAYAAYTAY ------AGYACNGARGARTGGGTNAAYTCNGTNAAYGARAARCCNTCNCCNYTNACNTTY TGYMGNYTNMGNGTNATHAAYGCNAGYYTNYTNMGNGTNGARATGGTNACNTTYGAYACN GCNGAYGTNYTNGAYTCNATHGAYATHGTNCARCAYAAYCAYCAYAARTTYGAYYTNAGY GARYTNTCNAARAAYATHTCNGGNCARATHGARAARGTNACNMGNGTNATGGGNGGNGAY CCNGAYAAYYTNAAYATHGAYGARATHGGNACNACN---ATHAGYAARAARATHCAYGAR ATHTTYGARGGNGAYAAYAARAAYAARGTNATHATHGGNGTNAGYGTNGCNGGNGGNGTN YTNTTYYTNATHGTNGCNYTNYTNGTNGCNMGNMGNGTNATGMGNGGNMGNMGNMGNCAY TCNAGYMGNMGNTGGGARAAYATGGAYGTNAAYTAYGGNAARMGNTAYTAYAAYAARGCN CCNGAYAARGAYGAYACNGAYAAYGAYTTYGAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GTNGARGARAAYYTNGTNACNACNACNCAR MGNGCNGTNCARGCNGARACNCARGTNACNMGNYTNAAYCARGARGTNAARCARYTNCAR GGNCARGTNMGNAGYYTNTCNGCNGARAAYGARGCNTAYMGNAGYGGNGAYGGNGGNYTN TCNGAYATHMGNGARMGNACNAARTAYGCNTCNGAYCARYTNAARACNGCNGCNGGNGTN GCNGARCARAAYYTNAARGAYYTNATGGCNGGNGTNGAYAARATGAARYTNYTNTCNCAR GTNYTNGCNACNTGGGARAARATHACNGARGTN---------GTNTTYCARAAYTGGAAR GTNCCNGCNMGNYTNGTNCCNGARAARGARTTYAAYTTYGARGAYCARGAYGCNYTNMGN GCNGTNATHACNGGNAARMGNGGNAARGGNCARAGYMGNCCNGARYTNYTNMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MGNCCNTGG TCNCCNAARTTYCCNGGNGAYATHCCNMGNYTNAAYAARTAYYTNMGNAARGCNGARAAR YTNAAYCCNGAYTCNCARTCNTAYTTYAAYGTNGAYAGYTTYAAYCAYCCNTGYGTNYTN GAYTTYTAYGAYMGNATGYTNYTNACNYTNYTNGTNCCNCAYACNATGACNGARATHAAY YTNACNCCNGAYAARCCNAGYAARAARCARATGGAYTCNAGYCCNGARCARTTYMGNCCN GAYTCNAGY------------------------MGNTCNTCNGGNGCNGGNTCN---ACN GARMGNGTNGAYCCNTTYMGNTGYGGNACNCCNTCNACNAGYAGYAAYYTNATHTCNACN MGNMGNMGNYTNGAYTAYGGNGARGCNGTNMGNAARCAYAAYTCNMGNCCNAARACNGCN TCNGARTAYATGGCNGTNYTNGARMGNGARMGNAARGTNMGNATGGCNGCNTCNGCNMGN ATHCARTCNGCNGGNGGNGCNAGYMGNCARACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AGYMGNYTNAAYMGNAAYYTNGAYCAYAARGTNTCNGAYGAR TCNCCNCAYATGCARGAYGTNTGYATHACNMGNGCNGTNCARAARGGNATGYTNGCNYTN ATHAARGCNATHATHCAYGGNYTNGGNCARACNATHACNAAYCAYGGNYTNGGNGGNATG GCNTCNGCNTAYATGGTNYTNGARGTNGCNCAYACNCAYTTYTCNGGNTAYMGNTAYACN GARAGYAARYTNGTNCAYACNGGNATGGCNGCNYTNACNTCNGARAGYAGYCARYTNAAR ACNTAYYTNTTYGARGGNYTNGTNGGNAARGAYMGNTCNMGNGTNTGGGAYCAYATGCAR TTYTGGGARGAYATGTTYYTNGAYGCNGTNGCNCARGARMGNGAYATHATHGGNATGGAY CARMGNCCNTCNGARATGATGGARMGNTAYGARTCNYTNGGNGARYTNGARMGNAARMGN YTNGARTAYGAYGARGAYAGYGTNYTNGCNGTNATGYTNTTYAAYYTNTCNGCNTTYATG YTNATGATGMGNGTNCCNAARCARGARATHAARAARAARGTNMGNMGNYTNYTNGGNAAR TCNCAYATHGGNYTNGTNCARAGYCARGARATHAAYAAYYTNYTNGAYCAYATHCARAAY YTNCARMGNCARAARGGNGARTTYCCNGTNCARGAYYTNAARACNAARGARGGNGGNYTN YTNCARGTNTGYATGGARGGNATHGGNYTNYTN---GAYATGGGNCARCAYACNTCNMGN CARGAYATHATHCAYGARGARGTNAGYGAYYTNAARATGMGNAAYTGGYTNTGYGCNAAY GTNGCNATGMGNGARGCNTCNAARTGYYTNGCNGTNMGNATHCAYGAYMGNATHTCNCAR ATHCAYAARGARATGACNMGNYTNGTNGGNMGNGGNYTNGTNTGYACNAARAAYTGYAGY MGNAAYGARMGNGAYTGGTGYGGNGTNTGYGTNMGNTGGTCNMGNGARATHATHGGNATH TGYGARCCNTGYTAYMGNCARMGNATHAAYTGGTCNMGNYTNAAYTCNGCNCARTGGACN AAYAAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MGNYTNYTNAGYGAYGCNAAYCCNGARAARGAY YTNGTNATHGTNCCNGCNYTNYTNGGNTCNCCNTCNGTNATGTTYGARCARGGNGCNTGY ACNGCNTTYTCNMGNGARGCNGTNGARATHYTNAARGAYGTNTAYCARATHGGNGAYTTY GARGAYGGNACNYTNMGNAAYGAYTGYGGNGCNAARGTNGAYAARAAYGARTCNGGNTGY TGYTAYATHTCNGAYTAYMGNCCNACNGTNMGNGAYAARMGNTCNAAYTAYAAYATHGTN GGNGTNATGTCNGTNGARTTYGCNGGNACNAAYGCNGTNGARCCNYTNYTNTTYGCNGCN GARAGYGAYYTNCCNATHYTNGAYTGYGAYGGNATGAGYMGNGCNTTYCCNGCNTTYGAR ATGTAYATHCCNTTYATGTAYGGNAARGARCCNTAYCCNGTNTCNGCNGTNGGNCAYGAY GGNTCNCCNCARMGNAAYGTNYTNYTNCAYGCNCCNAAYGCNAARYTNGCNGARCAYTTY ATGMGNGAYGTNGCNATHAARAAYGGNTGYATHTGYAGYGTNGCNGTNGCNYTNACNAAR TCNGAYGTNATHGAYAARACNGTNCCNTCNATHATHAGYAGYGCNTGGMGNYTNGGNGAY GCNATHYTNAARGCNMGNYTNCAYAARGARTCNGTNATHGGNGTNATGGTNAARCARGAR AAYGGNAARCAYATHATHTCNGGNAARATHGTNGAYGTNCARAARGARACNACNGGNGGN TTYAAYAARGGNCARTTYGTNGTNGARGGNCAYYTNGARTTYGCNGGNGARACNGTNATG ATHGTNTTYCARAAYGARTAYYTNGTNATHTTYCCNYTNGARAAYGGNGARMGNGCNGCN AAYAARGGNTGYGTNCCNGAYYTNATHTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GTN GARTCNMGNYTNTCNGAYATHCCNGAYGGNCARMGNYTNCCNATHACNGGNGGNTCNTCN TCNTCNTCNTCNTCN--------------------------------------------- ------------------------------------------------TCNGARGTNAGY GGNCARGTNTCNMGNYTNAARACNGAYYTNCAYGTNYTNAARMGNCARGCNCARYTNAAY ATGGARGCNATGMGNGARGARTTYYTNMGNGCNTCNTGYTCNATHAARAAYATHATHTCN ACNATHCCNGGNGCNGARAAYCARATGAAYTTYCAYAARMGNGTNGARGCNACNAARTGY AARACNYTNTAYGTNAGYGAYAARGTNATGGTNGAYCARGARYTNAGYGAYYTNGARAGY AGYGTNGARGARYTNMGNAAYGAYATHATHAAYCAYCARTGYMGNGTNCARATGACNGAY GTNGARGGNATGGCNYTNYTNYTNAGYAAYATHACNAARAAYYTNGCNGAYYTNAARYTN CARTTYCCNGARGTNCAYGARAARATGAARGGNGTNATGAAYMGNGARATGCARGTNGTN GTNGCNGARGARAAYTTYYTNAARGARGARCCNTGYAARATHGARAARTCNYTNCARMGN TGYAARAARYTNACNGGNACNYTNTAYACNYTNAARMGNYTNGCNTCNGTNCARGAYCAY MGNCCNCCNACNATHCCNAAYATHGCNTCNGCNGCNGCNTCNTGYAAYACNGAYGTNGAY CCNAARAARAAYYTNYTNGARAAYATHMGNGCNYTNGTNCCNGAYCAYGAYMGNMGNGTN CARGARATGGARGCNACNGARGCNGCNMGNATGMGNAARAARAARATHAGYAGYCARCAR GARGCNYTNAARTTYGGNAARAGYYTNGARATGGCNACNAARAGYYTNAARCCNAGYTCN MGNGAYGAYYTNMGNAARGCNGCNMGNAGYGCNTTYTCNAGYTCNTGGGTNTCNCCNCCN TCNTCNCCNCCNGTNGCNCCNTCNAGYYTNACNGCNCARATGACNTCNGAYGGNACNATH AAYYTNGTNYTNTCNGGNGTNGCNAGYCCNAARTCNCCNACNAAYCCNGGNACNTTYACN ATHACNYTNCCNAARGAY---------TCNTCNAARTCNAAYTCNAAYACNATHYTNGCN ACNAGYAARCCNGARAAY---AAYAARCARAARAARATHCCNCCNCCNCCNCCNCCNMGN AARGGNAGYMGNCCNACNTCNACNAAYYTNCCNGCNATHAAYGGNGGN------------ ------------GARCARGARAAYGARACNCCNCARTTYGTNGGNGGNATHYTNGGNCAR CAYGCNYTNTCNGGNGGNCCNYTNTCNTCNACNCCNAARCCNAGYTCNCARCARMGNGCN YTNTCNACNTTYGARAARGAYATHGCNTCNGGNATHTAYGCNAAYATGAAYMGNCCNGAY YTNCARAAYCARAGYTGYACNCCNCARCARATGYTNGAYAARGCNCCNYTNCCNACNGAR ---------------------------GTNCCNGCNCCNYTNGTNTCNACNACNTGYGTN GAYMGNAAYGARMGNGGNAGYAGYAGYGARAGYAAYAGYAGYAGYTCNGGNACNAGYATG GGNTCNCARCARTCNGTNGTNAAYGTNGCNMGNTCNGCNTCNACNATGMGNAAYACNAGY AARCCNAARCCNGARCCNCCNMGNMGNCAYTCNAGYYTNYTNTCNAAR------------ ---------------------GAYAARTGGAAYAAYGTNAARGCNGGNGTNTTYYTNTCN TCNATHACNGGNTGYTCNATHYTNGCNGGNTTYGGNATGACNYTNGGNGGNATHAARAAR AGYGAYCCNGAYAAYTTYGCNAARGGNGTNGTNGGNGCNMGNGARYTNCAYGARACNGGN YTNGCNGTNGCNTCNMGNACNYTNGCNMGNGCNACNYTNTAYACNGTNTCNGGNTTYGGN YTNGTNTGYTTYGCNGTNTGGAARATGATGGGNGTNAAYACNTTYGARGARTTYMGNTGG AARGTNGGNAAYGCNYTNCCNMGNYTNAARMGNCARGARAGYACNGGNMGNAAYGARTTY TCNTCNATHMGNGAYYTNTTYGARTAYATHATHGARGARGAYGARAARGARAARAARYTN AAR------------GARGAYGARTGYCARCAYTAYAARCARMGNYTNGARAGYYTNAAR ATHGTNYTNMGNGGNTTYCARGAYCARGTNGCNYTNTAYAARAAYMGNTGYYTNGGNGTN GAYACNATHGTNYTNGCNYTNAARGARTCNAARCARGARAAYGTNAARYTNTCNAARCAY GTNAARGCNYTNGARACNGCNATHTCNATHYTNCARAARMGNYTNACNAARAAYGGNYTN TCNAAYAGYGTNATHGTNCARGAYACNGARYTNTTYGTNCCNGGNGCNTCNAARCARACN YTNGAYAAYYTNGCNAARGARACNGCNMGNYTNMGNAGYYTNYTNAARCAR---GARAAY AGYYTNGGNAARAAYTCNAAYGARAAR---GARGAYATGAARGCNGTNYTNGARCARYTN GARYTNGARAAYAAYGARYTNAARAAYAARYTNAARGAYATGGGNATHATHAARATHACN YTNGCNAARAAYTAYGARGAYGTNATHGARAARATGTCNAARGARMGNGARGARGARMGN YTNAAYTTYGARCARGARYTNAARGCNATGAAYTCNMGNGGNTCNAAYGARAGYAAYTTY GAYGARYTNAARACNYTNYTNMGNMGNACNGTNGARAARTGYTGYCARYTNGARGGNCAR YTNCCNYTNCAYGCNGTN------GGNGAYAAYMGNYTNGTNGGNAARATGTAYGARGAY TCNYTNGGN---------GARMGNCCNGCNATHTCNCARGARGARTAYGAYAARGCNGTN GCNATGAAYCAYAARTGGCAYCARTAYAAYATHGARMGNGARAARTTYATHCARTCNYTN CARGAYCARATHMGNGARYTNCCNGAYCCNCAYCAYATGACNGCNATGYTNGARGARAGY ACN---------AARCARAARACNGGNGARYTNACNTCNGARATHAAYMGNMGNGGNGCN CARATHTCNGARYTNAGYAARCARGTNCARYTNTAYTCNYTNGARATHGARAAYYTNMGN ACNTGGAARGGNCARATGCAYCARGAYAAYAGYACNGTNGARATHYTNAARCARCARATH CARGTNTGYACNGARGAYTTYAAYACNGARMGNMGNGAYMGNGARCARGCNGTNCARAAR GCNMGNGARYTNCARGARGARATHGAYMGNYTNAARGTNGARAGYGTNACNYTNGTNAAY CARGTNGARAAYYTNAARAARATHAAYGARCARCAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNGGNATHGTNTGYCAY AGYTGY---------CARTAYYTNACNTGYGCNGAYCAYTAYGAYGTNAAYAARTAYGAR GGN------AAYYTNGGNGAYTGYGGNGAYGAYATGTAYTGYGTNAARTAYAARACNATH GTNTGGATHCAYGAYTCNGGNGARATHTCNGGNAAYTCNACNMGNTCNTCNGTNGTNACN MGNACNTGYGARTCNAARAARGGNAARTCNGARGGNTGYACNGGNTGGAARAAYAAYGGN GGNGTNACNYTNAARTGYTGGTGYGGNTCNGAYGGNTGYAAYGGN--------------- ------------------ATGGGNAAYMGNGGNGGNYTNCCNATHAARAAYATHGTNACN GCNATHTTYATHYTNYTNTCNYTNTAYYTNYTNTAYATHTAYAAYGTNTCNCARAAYMGN YTNCAYGAYACNGAYATGACNGCNGCNMGNTAYMGNMGNGARGCNGARGARMGNGTNAAR GARATHCARACNYTNATHTCNGCNAARGAYGAYTTYCARGARMGNTGYGARGAYGARAAR MGNCARTAYGTNAGYMGNATHAAYTCNATHAAYCARAARCARGGNYTNYTNGARAGYCAR AAYAARGARGTNGARGCNGAYYTNATHAARGTNAARCARGAYATGGARAAYYTNMGNGCN GARCAYGCNCARACNGARGCNCARCAYGCNCARGARTAYCARGAYYTNAARCARAAYAAR GAYMGNGARATHYTNGAYATHACNGAYCARGTNAAYAAYGCNAARCARYTNAAYGAYCAR ATGCARAGYTCNATHYTNTTYYTNAARGCNGARATHCARTCNTAYAARACNGCNAARGAR ACNYTNATHGCNCARAAYTCNCARYTN---CARGCNYTNCARGARCARCARAAR------ ---AARCARYTNGARYTNCARYTNCARAAYGARGCNAAYGCNMGNCARGCNCARCARCAR AARCARATGAAYTAYCCNACNTGGGGNACNYTNATHCCNACNTCNGGNYTNATGGGNGCN ATHGCNGGNCCNATGTGGACNTCNCARGGNGTNTAYATHACNTCNTTYGGNGARAGYTAY GCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CARGARGCNTAYGCNTGGAARYTNAARGARGTN AARAARACNATHAARGAYACNATHTTYATGAAYGGNGCNATHTGYGAYGARGTNYTNMGN ACNGARGARAARYTNGCNMGNGCNAARGARGARMGNMGNTTYYTNYTNMGNAARYTNYTN CARTAYCARTCNGTNAAYGARACNTCNGGNTCNGTNAGYAARGCNGAYGTNTCNTCNACN GCNGCNMGNGGNGTNAAR---GGNGCNGGNCARGARAAYACNGTNGGNACNGARGTNACN AGYAARGGNTCNAARGCNGTNAARMGNAARYTNAAYGCNTCNACNTCNGCNGCNGGNGGN YTNAGYATHGTNTCNTCNYTNCCNTCNGGNGGNGCNAGYGGNGCNAGYGCNTCN------ ---GAYAARAARAARAARCARCCNCARTCNGCNAARGAYATHYTNGAYTCNYTNCARGGN MGNCCNAARAARAGYAARTCNGCNGGNAARAARACNATHCCNCCNYTNATGYTNGAYTCN YTNGGNMGNCCNYTNATHCCNATGATGYTNGGNGAYATHACNYTNCAYAGYATGGGNGAR ATHGTNACNGAYAARCCNAGYTTYCAYTCNGCNGARGCNATHTAYCCNGCNGGNTAYTGY ATHACNMGNGTNTTYATHAGYYTNCAYAARCARGAYGCNAARTGYYTNTAYACNTGYAAR ATHTCNGARGGNGAYAAYGGNCCNYTNTTYGARATHGCNCCNGARGAYAAYTCNGAYATH GTNTTYAARGCNAAYAAYCCNGCNGARTGYCAYAGYYTNYTNYTNMGNGCNGTNAAYMGN TCNMGNGGNGTNGARGTNYTNCCNACNGAYACNCARGGNYTNGAYTTYTTYGGNYTNTCN CAYGCNGTNATHCARAAYYTNATHCARTCNATHCCNGGNTCNMGNAARTGYTCNMGNTAY AARTGGGTNAARTTYGARATHAAYAARGCNGARTCNAAYGARAAYTTYGTNGTNGGNAAR AAYGAYCCNACNATHAAYTAYGARGCNTTYATHACNCAYYTNGCNGCNYTNACNCARATG MGNCCNGGNTCN---TCNTCNCARGGNGARAARTCNACNAGYYTNMGNTCNYTNYTNACN AAYTCNAGYGCNATGAAYTTYCAYATHGARAARACNGTNGCNTCNGGNGGNMGNYTNGGN AARATHAGYCARATHGTNAARGGNAAYACNATHACNYTNGARACNCCNATGTGYACNYTN TTYACNAARGGNGGNAGYGCNCCNTAYYTNGGNYTNAAYATGYTNGAYAARATHAARAAY GTNCCNGARATHGCNACNATGAGYGTNAAYTCNTTYGTNGAYCAYCAYGAYAGYATHMGN AGYTAYGGNAARGGNYTNGCNGAYTTYAGYTGYATGAARGARMGNYTNATHTTYTCNTCN YTNTAYGAYTCNAGYGTNACNGTNCARTCNGGNAARAAYGAYAARTCNGGNATHGCNGTN TGGGGNAARGGNGGNAARACNATGYTNGAYCCNAARYTNTAYATGMGNATHCARGARGCN YTNCARCCNGAYTGGATHYTNGCNYTNGGNGAYGGNGAYACNGAYCARGARAAYGGNGAR AARMGNAAYGCNAARGCNGTNGAYMGNACNYTNGAYTGGYTNGAYGAYATHGTNTCNGCN AARGARAARTCNGARYTNYTNAARAGYTCNAGYYTNATHGGNGTNATHACNGGNGGNTTY AGYGARMGNCARMGNCARMGNAGYGCNACNGARACNTCNGCNMGNCCNGTNCAYGGNTTY YTNYTNGARGGNTTYCAYAARGGNATHCARGARGARAAYGTNTTYGARAAYMGNGTNTTY CARAGYATHYTNTCNAARACNYTNAGYTAYYTNCCNGARAGYAARCCNMGNATHACNGAR AGYCCNTGGTCNCCNGCNCARGTNACNCARGCNTTYAARYTNGGNGTNGAYATHTTYTCN AGYTCNTAYCCNCAYACNYTNACNGARAARGGNCARGCNYTNACNGCNGAYTTYMGNYTN CCNAARCCNTCNTCNACNGARACNATHGARAARGGNCARGARAAYAARGGNAGYGCNGAR MGNCCNGTN---ATHGAYYTNAAYGAYAARAARTAYTTYGARGAYTTYGGNCCNGTNATG GARGGNTGYGARTGYTAYACNTGYMGNACNTTYACNMGNTCNTAYATHCAYCAYYTNYTN AAYACNTCNGARYTNYTNGCNTTYGTNYTNYTNACNATHCAYAAYTTYGARCARTAYTTY GARTTYTTYMGNTGYYTNMGNCARGCNGCNAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNTGYYTNGTNATHGCNGTNGCNACNYTNTGYYTN TTYCARATHCAYACNMGNATHYTNGAYAARGTNYTNCCNTCNTCNAARATHCCNGTNATH AARGCNGARGAYGARGGNGCNGAYGGNGCNYTNGAYACNGTNCARAAYTTYMGNTAYAGY YTNATHGARATGCAYGAYTTYGTNATHAARTGYAAYGARTAYYTNACNCARTTYTAYTCN ATHYTNAARTGGGAYTCNCCNYTNYTNTCNYTNATHTAYCAYGCNGARATGTGYATHTTY ATGATHTGYYTNGTNATGTGYCCNGCNMGNTGGAAYTGYTTYGTNYTNATHAAYTGGTTY TTYYTNTGYCAYCCNTCNATHYTNCARAARTAYTAYAGYTAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARCARGGNAGYATHAGYTTYGAYGTNATHYTNAARCCN GCNGCNGCNGAYTCNCCNMGNCCNGTNYTNCCNCAYTCNCCNMGNGAYAAYAARCARAAR GARYTNTCNGARGARAARATHGCNATGAARYTNAARAARGCNGARCARMGNMGNAGYYTN ATHGARCARGARMGNYTNGAYCARATHGCNAARGARMGNCARAARGCNATHGARGTNATH ATHAARGCNCARTCNGARAGYCARGARTTYTCNAARAARACNGARGARAARYTNAARMGN TCNATGGARAGYMGNMGNGARAAYMGNGARCAYCARATHMGNGCNYTNCARGARMGNYTN MGNGARCAYTCNGTNAARGTNCAYGARGTNCARAARGCNGGNATGGARATGGTNAARGAY TTYGARGCNAARGCNGARCARAARYTNACNCARAARATGGGNACNTAYGARGARAAYMGN AAYAAYCARYTNTGYGCNATGYTNTCNAARYTNCARGARCAYGCNAGYCAYATHAAYGAR GTNTGYGTNGCNAGYGARAAYMGNGGNCCNAAYACNGAYGARYTNCARGARCARYTNGTN CARAARATGGARAAYGCNYTNAARAAYMGNGARGARCARYTNMGNTGYATHCARGARMGN YTNGCNGARCAYGARAAYAARATHAARGARGTNCARMGNAARAARGGNATGGTNTCNTCN GGNGARCCNGTNCARTTYAAYTGYCAYYTNTGYCCNGCNACNYTNAARTCNGARTTYTTY YTNMGNTAYCAYYTNGCNAARCAYGGNGGNTTYCCNCAYAARTCNGTNYTNTCNACNCAR GAYGGNGTNYTNATHTGYGCNMGNTGYGAYTAYATHGCNCARAGYAAYAGYGAYYTNGCN AAYCAYGTNTCNACNCAYGTNACNGAYMGNMGNTAYACNTGYTCNYTNTGYGARCARGAR AGYCAYCAYAARAGYCARATHCAYGAYCAYATHMGNMGNCARCAYGGNCCNGAYGCNCAY GCNAARGTNYTNGAYMGNGARAARMGNAARMGNAARAAYYTN------AARGTNGTNAAY YTNAGYCCNGTNGTNATGTAYGGNCARMGNTAYCARGCNGARGGNCCNCCNCCNTAYCAY CCNTGYACNGTNAARCARTGGGCNTCNMGNGTNYTNTCNTTYTCNTCNCARTAYAAYAAY ACNTCNTGGAGYGCNGTNCARGTNYTNGGNGARCCNAARGTNTAYCCNCARCAYGGNGAY ATHCAYGGNGCNTGGGCNACNGCNATGTGYGAYGCNAAYCARTTYATHGARGTNGARTTY GARATHCCNGTNMGNCCNACNGAYATHCAYATHTAYGARACNTTYAAYCCNGGNGCNGTN GTNMGNATHAARGCNMGNGARTCNACNGGNCARTGGGTNYTNGTNTGGAARGCNAAYCAY CCNACNAAYATGAGYCARAGYMGNATHTTYTCNCCNCCNYTNTCNGCNAARATGATGAAR ATHGGNCARYTNMGNATHGARGTNGAYTGYACNGCNGCNMGNACNTGGTGYGARYTNGAY GCNGTNCARYTNGTNGGNGTNMGNGAYGGNGCNGTNGCNCCNGTNGAYGAYACNCARTTY GTNGCNGAYATGCARCAYYTNGTNAAYAAYAARYTNCAYAGYGAYGTNAARTTYAAYATH GAYGGNAARGARGTNTAYGGNCAYAARGCNATHYTNGCNACNMGNTCNCCNTAYTTYGCN CAYATGTTYAAYGCNGARGCNAGYTCNAAYGCNAAYYTNAARYTNCCNCARYTNTCNTTY GAYGAYYTNGTNGCNGCNATGCAYTTYATHTAYACNAAYMGNYTNCCNGCNGARYTNTCN TCNGCNMGNYTNGCNACNYTNTGYAARACNTCNGCNACNTTYGARYTNCCNGARATGAAR ACNGCNACNYTNTAYAARYTNGTNGARAARATGACNTGYCARAAYGTNGTNGAYATHTAY AARCARACNCARGAYGAYACNTCNYTNGAYGGNGTNAARAARGCNTGYTGYAGYTTYATG GCNTCNCAYYTNAARGARATGTCNAGYGARAARGCNTTYGCNACNYTNCCNCARAGYGTN ATHGTNGAYGTNGTNCARGARGCNACNATGGCNYTNTGYYTNAAYGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARCAYYTNTTYCAYTCNATHGCNCAYAAYGAYCCNGCNATHAGYATHGTNGGNCCN ACNATHYTNGARCARYTNMGNCARGGNTCNYTNCARTAYGARAARACNMGNGARGAYCCN TTYTGYAGYGTNMGNAARMGNYTNYTNAARTTYCARGARGARATGTCNGTNGTNGTNGTN GTNTGGMGNGAYTGYCARCARYTNATHGARAAYTAYTGYCARGARGARTTYACNAAYACN CARAARCARGTNTCNCAYMGNGCNAARAAYTTYATHACNCARCARMGNCARYTNYTNAAR AAYCAYYTNATGAARGAYTCNTTYATGGAYGARGARACNATGAARAGYYTNGTNTCNGGN CAYAARGCNTCNACNGARAARGTNYTNTGYCAYMGNTGYAARMGNGARMGNTGYACNTGY GAYGARTGYACNATHACNCAYATGATHACNTGYGGNATHATHAAYACNGAYAARGGNACN ACNYTNCCNCCNCCNCCNAGYTCNTTYAAYTTYGCNYTNGAYCAYACNCAYAAYGTNATG GAYATHACNCCNCCNTCNATGTCNAGYACNACNTCNAGYAGYGGNTCNGTNTCNCCNATH AAYGTNGAYGAYAARAAYCCNGGNTAYGAYTGYGARMGNMGNGAYGCNATGYTNMGNACN ATGCARGGNYTNGAYAAYATHGAYGAYAAYGCNGGNGAYGAYGARGAYGAYGAYYTNGAY GAYGCNGARAAYTGYATHGAYCARAAYGAYGGNAGYGAYGARCCNCAYGCNATGCARTTY CARCCNMGNATHGAYAGYCAYYTNTCNAARCARYTNGARGCNGARATHGCNAGYTCNGGN GTNTCNTCNAGYGAYGTNAAYGAYTAYGTNTCNACNGAYGAYGCNGCNGAYCARYTNGGN AGYGARGCNAAYYTNATGGGNTCNAGYGTNTGYGCNGCNTGYCARTGYCAYGCNTGYYTN AARCARAGYGGNCAYGTNGTNTCNACNTCNYTNCCNYTNCARGTNCCNGTNTCNCCNCCN CCNGCNGARYTNAAYYTNTAYCCNCAYATHCAYGGNYTNCCNCCNCARMGNTAYATGTTY GGNYTNCCNTCNCCNYTNYTNCCNTCNGTNAARYTNCCNYTNAARYTNGAYTTYGAYGAY CCNGCNAGYATHCAYGAYCAYYTNTAYCAYGCNTAYAGYGAYTGGGAYAAYCCNMGNCCN GGNTCNYTNGCNGCNCARCAYCARCAYCAR---CCNAAYMGNTTYTCNGGNYTNACNTCN GAYYTNYTNCCNCCNGCNCCNGTNGTNGAYGGNGTNCCNGCNTTYAGYTTYGARGCNYTN AGYYTNACNTCNCAYTGYACNCARGCNGTNACNAAYACNAGYAGYGCNTTYAARTCNGTN ATHAAYAAYCARAGYTTYGGNGAYTTYTCNTCNAGYAGYAGYGGNAGYAGYGCNGARGGN AGYTCNGTNGAYCCNACNNNNNNNNNNYTNGAYTTYTCNTCNYTNYTNAARATHCCNCAR GCNTGYYTNAAY---TCNTCNTCNYTNTCNCAYCCNYTNYTNACNTCNTCNGTNCCNTCN GCNCCNTCNGTNATGTCNGCNYTNCCNGTNTCNTCNTCNGTNACNYTNTCNAARACNACN GGNTCNTGYCAYGGNCCNCCNTCNTCNMGNCCNATHCCNYTNGGNGGNAAYACNACNTCN AGYAARTGGGARAAR---CAYTCNYTNCARTGYAARAARTTYACNGCNGCNGGNCCNAAY AARTTYGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGGGGNTCNATHATHTCN AARCCNACNCARGCNATGCCNAARCAYTCNYTNTTYGGNACNGCNYTNGARAAYGTNGAY MGNGAYAGYYTNAARAARATHGARGGNMGNTAYATHCCNGARGGNTTYGTNAARGARATH CCNAAYMGNTAYCCNYTNCCNCCNCAYATHAARGAYACNATHCCNGGNMGNGAYTAYYTN GARACNTCNMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHTAYYTNGTNGCNTCNAARMGNMGNATGMGNAAYGTNACN AAYTAYTTYATHGCNAGYYTNGCNGTNAGYGAYGTNATGATHGCNATHATHTGYATHCCN TTYTTYTTYGTNGCNAAYATGYTNTTYGAYGARTGGCCNTTYGGNAGYGCNYTNTGYCCN ATHGTNACNTAYTTYCARGTNGCNGTNGTNTTYCARAAYGCNTAYACNYTNCCNTTYYTN MGNMGNYTNGGNAARMGNMGNTGYYTNCARGTNGTNGTNYTNTGYTGGTTYYTNGCNTTY YTNACN------------------------------------------------------ ------------------------------------------------------GARGAY TGYTTYGTNATGAARGAYCCNTTYTCNACNATHGGNGGNTAYATHAGYATHGGNGCNGTN TGYTCNYTNTGYAARGARAAYGTNTGYATGTCNACNTGYTGYAGYYTNTTYTAYACNCAR MGNTTYTGYYTNMGNTGYGCNTCNGARAAYYTNCAYGARTTYCCNYTNGARYTNCAR--- ------------------------------------------------------------ ------------------------------------AAYGGNGGNTTYGTNCAYAGYATH CARACNTGGGCNGCNGAYGCNCAYAARYTNAAYGAYMGNGARTAYGTNGARAAYAARGAY TAYGCNTAYGTNGARGGNATGGAYGGNCAYTCNGGNGGNACNAARGAYTAYGCNAARGCN YTNTCNAARTCNATHYTNTTYTAYAAYGCNCARMGNTCNGGNAARYTNCCNMGNAAYAAY CCNATHCCNTGGMGNCAYGAYTCNGCNYTNAAYGAYTGYGTNCARGGNGGNTGGTAYGAY GCNGGNGAYTTYGTNAARTTYGGNYTNCCNATGGCNTCNTCNTCNACNYTNYTNYTNTGG TCNYTNCARMGNTTYAARGAYGGNTAYGTNAARGCNGGNCARYTNAAYCARATGTAYGAY ATGATHAARTGGCCNYTNGAYTAYTTYYTNAARGCNTGGAAYCCNTCNMGNAARGAYYTN GTNGTNCARGTNGGNGAYGGNAAYATHGAYCAYGAYTAYTGGGGNMGNCCNGARGAYATG ACNATGAARMGNCCNTGYAGYCAYTAYAAYAARMGNCAYMGNGGNAGYGAYATHGCNGGN GARACNGCNGCNTCNATGGCNGTNGGNTCNATHGTNTTYAARGAYAARGARAARCAYTAY GCNTCNCARYTNYTNACNGCNGCNGARAGYYTNTAYGCNTTYGCNAARAGYCAYMGNGGN GTNTTYACNGGNGCNTCNCCNTTYTAYACNTCNAGYGGNGAYCARGAYGARYTNTGYGAR GCNAGYATHTGGYTNTAYMGNGCNACNMGNAAYAAYAARTAYYTNAAYGAYGCNAARMGN TTYGTNGAYACNTCNGGNGCNTGGGCNATHGAYTGGGAYAGYAARCARYTNTCNTGYCAR GCNYTNYTNTAYGAYACNACNCAYGAYAAYCARTAYAARGARGCNGTNACNGGNTTYTTY GAYGAYTGGTTYCCNGGN---GGNGTNAGYTAYACNCCNTGYGGNYTNGCNTGGMGNGCN AARTGGGGNTCNAGYMGNTAYGCNGCNAAYGCNGCNTTYYTNGCNYTNGTNGCNGCNGAY ATGGGNATHAARGCNAARTCNTAYMGNCARTGGGCNGTNGARCARATHAAYTAYYTNYTN GGNGAYAAYCAYCAYGAYGGNGGNTGYTAYAGYTTYGARGTNGGNTAYGGNCAYAARTAY CCNAARCARCCNCAYCAYAGYGCNGCNTCNTGYAAYCCNCAYATHYTNCARGGNGCNYTN GTNGGNGGNCCNGAYGCNAAYGAYAAYTAYAARGAYGTNMGNGCNGAYTAYGTNCARAAY GARGTNACNACNGAYTAYAAYTCNGGNTTYCARGGNGCNYTNGCNGCNATHAAYCARYTN GTNGCNACNAAYCAYYTNCCNCCNACNCAYAAYAARTGYCCNTGY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TCNMGNGGNGGNCARTCNCARTCNTCNMGNTAYACNAAYGTNGAYAAY TTYAARCAYYTNGARTCNGARAARCARAARYTNGARYTNGAYAAYATHYTNCARGCNGCN TTYCAYCARGCNGGNGARAARGCNTTYGTNATHCARAAYATHCAYTCNYTNTCNCCNAAR GCNGCNYTNYTNYTNCAYGGNGTNTGYGAYGGNGAYAAYGCNCCNTTYAARGAYGTNATG ATHGTNYTNACNTTYCAYGTN---------GARAAYGAYCARGCNATHCAYATHCAYAAR CARGTNGARCCNYTNYTNACNCARATHTGGGGNMGNGAYYTNGAYATGGAYAARYTNTCN GCNGTNATGAGYMGNATHGCNAAYAAYCCNGTNGTNYTNAAYCCNGARTCNGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TAYTAYGCNACNGAY TCNAAYMGNTGGYTNATGAARGARGAYMGNGARAARYTNMGNAARMGNGARGARGARYTN MGNGARTCNMGNCAYGGNTCNMGNMGNGAYMGNAARATHACNTTYGAYATHGCNGGNMGN TCNATHAARGTNGTNGAYGCNGARGARAAYGTNGGNAARACNATGTAYAGYATHGARGAY TCNGTNGTNCARGARGTNCAYTAYGGNAARAARAARYTNAAYGGNAAYGCNTCN---ACN YTNGTNAAYCCNGCNYTNGARACNAARCCNCCNATGTTYYTNGAR---AGYGARACNGTN AARGGNCCNGAYGTNAAYAARGTNGTNTCNGCNGARMGNTTYAAYCCNYTNTCNTCNTCN MGNMGNATHCARGAYMGNGARYTNCARGARATGAGYGAYGARGGNATGTGYATGAGYATG CAYCARCCNTGGGCNTCNYTNYTNGTNTGYGGNATHAARATGCAYGARGGNMGNTCNTGG TAYACNTCNCAYMGNGGNMGNYTNTGGATHGCNGCNACNGCNAARACNCCNYTNAARGAR GARATHACNGARYTNGARCARTTYCAYAARCARCAYTAYCCNGAYTCNAAYATGACNTTY CCNAAY---TAYCCNACNGGNTGYYTNYTNGGNTGYGTNAAYGTNGAYGAYTGYYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TAYCARGCNCARAGYGAYAAY YTNCCNGGNGCNTTYGTNGAYGGNCAYGTNACNTAYGGNTCNTAYCAYAGYYTNGARYTN GTNGARGTNGAYCCNGGNAARCAYGTNGARATHCAYATHMGNTAYATHCARACNATHGTN GTNATHMGNCARATHGGNMGNTTYTTYACNTTYTCNATHCARATGCCNGARGAYYTNATH AAYTCNAGYCARAAYGCNGAYYTNCARYTNTGYGGNMGNGGNTGYCCNAAYTCNGARYTN GTNGAYTAYAARAARTAYYTNGCNACNMGNAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CARCARGARTTYTAY YTNCAYTTYCCNAGYATHCARMGNYTNAARATHTTYCARGTNMGNAGYGARACNAARYTN ATGGTNCCNMGNATHGCNTGGMGNACNYTNCAYATHYTNAARTAYTTYTAYATHTTYTAY TTYYTNTTYGGNTCNYTNCCNMGNAGYTGGATHTGYGCNTCNTTYGGNATHGAYGAYGAY GCNTAYGCNGCNCCNYTNGAYTCNATHYTNGGNYTNATGAGYYTNTCNYTNTTYTGGAAR ACNTAYYTNYTNTCNTAYATHTTYACNTTYACNYTNTCNTTYACNGTNGCNYTNGCNAAR ATHTTYCARACNGARCAYYTNGARTTYCCNATHACNAGYATHYTNGARGAYACNAGYGAY MGNACNYTNYTNGARGCNYTNGCNTGYTCNTAYGCNCCNYTNYTNCARCAYYTNGCNCAY CAYGAYYTNGTNTGYATHGGNAARTTYGCNTCNTCNMGNYTNCARGARATHYTNAGYYTN AGYCARCCNGGNGGNCAYCCNAARGTNTGGATGGCNGTNAGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNCARGCNATHCCNTAYACN TTYTAYGARCCNGGNACNGCNTAYTTYTGGGTNCAYTTYGGNYTNGTNATHYTNGGNTTY GTNYTNGCNGTNATHACNTGYATHGTNCARTGGMGNAARCCNGCNCCNTAYGGNAARCAY GAYGTNACNGAYGARAAYTGGGGNCCNATGATHCCNCARMGNYTNTCNCAYYTNYTNTCN GAYACNATHCCNGGNGTNATHATGTTYACNYTNGTNTTYTTYYTNTAYAGYMGNGARGAR AGYGAYAARAARGCNGTNAAYTAYGTNTTYTTYGGNYTNTTYYTNGTNCAYACNATHCAY MGNGGNATHATHCAYCCNYTNGTNATGAARTAYAARAAYACNAARGTNCCNYTNGGNATH GGNYTNGGNACNATHTTYCCNAAYATHYTNTAYCARTGGYTNATGGCNAAYCAYATHGGN GTNGCNATHTAYGAYGAYTCNTAYCCNTAYGAYCCNMGNTTYATHYTNGGNATHYTNYTN TTYATHTTYGGNTTYGTNGTNAAYMGNTGGTCNGAYTGGAARYTNMGNTCNYTNMGNAAR AARAARGGNGCNCCNGARTGYGGNGAYAGYAARGGNTAYTAYATHCCNTAYGGNTTYATG TTYAAYTTYATHTCNTGYCCNAAYTAYTTYGGNGARYTNGTNCARTGGACNGGNTGGACN YTNGCNACNTGGTCNYTNTCNGGNTTYGTNTGGACNTGYTTYGCNGCNGCNACNTTYTTY GCNMGNTCNMGNCAYAAYCAYCARTGGTAYMGNGAYCAYTTYGARGAYTAYCCNGCNGAY MGNAARGCNYTNATHCCNTTYATHTTY--------------------------------- ------------------------------------ATGTTYTCNAAYACNAARAAYMGN AARAAYGGNATGACNATHGARGARGARATGTCNGCNTTYTTYCCNTCNYTNAAYYTNAAR TCNYTNGAYATGGARAGYATHACNATHGCNGAYYTNMGNCAYAARTTYGARMGNAAYAAR MGNMGNAARYTNACNYTNGARGARAARMGNAARTTYGCNAGYYTNTGYCAYGARTTYGTN ---------------CAYMGNATHATHGARAARMGNMGNMGNGAYMGNATGAAYAAYTGY YTNGCNGAYYTNAGYMGNYTNATHCCNGCNAGYTAYCAYAARCARGGNCARGGNMGNATH GARAARACNGARATHATHGARATGGCNATHAARCAYATHAAYATGYTNCARGGNMGNGTN GAYGARYTNGARAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------ATHCARACNMGN TTYGCNGCNTTYGGNACNAARYTNGARCCNAAYMGNAARYTNAARMGNGGNGGNTCNACN YTNYTNMGNTAYGGNMGNAGY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNYTNAARGARCAYGGN CAYGARTCNGAYAARGAYGAYACNGARGARTCNGARGARGARGARAGYGARGAYGAYGAY AARGAR------TAYAARAAYGTNTTYGAYMGNGAYGGNAARGTNCCNAGYGTNGCNMGN GTNGAYATHGGNGGNATGACNTAYATHAARACNGGNCCNGGNACNYTNGARYTNTCNTCN CAYGGNAAYMGNAARCARGCNGCNAGYMGNGCNGTNCARMGNAGYYTNAAYATHGTNGCN GCNAARGARAARAARAGYAGYAGYAARMGNAARACNAARMGNMGNCAYTGYYTNTTYTTY MGNMGNTTYGGNAARTGYCARMGNGGNGARGCNTGYCARTTYATHCAYGAYAARGAYAAR GTNGCNGTNTGYACNMGNTTYYTNMGNGGNCARTGYGAYGCNTCNGCNTGYYTNTTYTCN CAYGAYGCNTCNGARCAYAARATGCCNGTNTGYYTNTTYTAYYTNMGNGGNYTNTGYTCN MGNCARGAYTGYYTNTAYYTNCAYGTNAARGTNAGYCCNGAYGCNCCNGTNTGYGARAAY TTYYTNYTNGGNTTYTGYCCNYTNGGNCARAARTGYAARAARYTNCAYTCNTTYGTNTGY CCNTCNTAYGCNGTNTTYGGNCARTGYCCNYTNGCNGARAAYTGYCCNATGCCNCAYMGN MGNGGNAAR---ATGCCNACNTTYAARATHGARACNAAYYTNACNMGNGAYCARATHCCN GARAARTTYYTNCARGAYGCNACNGARYTNATHGCNTCNGARYTNGGNAARCCNAGYTCN TTYGTNTGYGTNCARGTNTGYCCNGAYCARATHATGAGYTTYGGNGGNACNACNGARCCN TGYGCNAAYATHTCNYTNATGTCNATHGGNGTNGTNGGNCCNGAYAARAAYMGNAARATG GCNCCNGTNYTNTCNAARTTYATHGARCARCAYYTNGGNATHAARCARGAYMGNTTY--- ------------CARGGNYTNAAYYTNTCNGARAARAAYYTNAAYCAYATHYTNTCNATH TCNAARGAYTGGTGYYTNTCNAAYGGNGTNGGNYTNAARGCNGGNYTNGARGARCCNGAR TGYTCNAARATHGTNGCNGCNCCNTTYGCNYTNTTYCCNAGYYTNGTNCCNTCNGCNYTN YTNACNTCNGCNAARACNACNATGCCNCAYTTYAGYMGNYTNATGCAYAARGTNGCNYTN GAYCAYCARTTYYTNGARTCNGCNYTNAARAAYGTNATHGARGTNGAYGARTTYACNYTN GGNGTNTGGAAYGTNTAYTGYMGNGTNMGNCARGAYGGNATHAARCARCCNATHATGYTN GGNYTNTTYMGNAAYGAYTTYATGATGAAYTGYYTNGAYCARGAYACNAARAAYCARCAR ACNGGNGCNGAYAAYYTNGARYTNAARCARATHGARTTYAAYACNATHGCNTCNAGYTTY GCNGGNYTNGTNCARAARATHGGNCAYYTNCAYMGNYTNACNYTNGGNYTNGCNGGNAAR GAYTTYACNCAYGAYCARGCNCCNGAYAAYMGNCCNGCNTCNGGNYTNGCNTCNGGNYTN GTNAARGCNTGGGARYTNTAYGGNAARCCNAARGCNGTNATHGTNTTYGTNGTNAGYGAY TTYGARMGNAAYATHYTNGAYCARMGNGCNYTNGARTTYGARGTNTAYAARATHAAYGAR AAYGTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGGCNGARAGYTGYAARGAYYTNTTYTCNAAYGCNTTYTAYTAYAGY TCNATHTCNTTYTCNYTNYTNYTNGCNAARGARAGYGGNATHTTYTCNTCNYTNYTNGCN GCNACNAARCCNYTNACNGCNYTNGARATHGCNGAYGGNAAYMGNATHMGNGARMGNTAY GTNMGNGARATHYTNGGNTGYYTNTCNGGNTGYAARGTNGTNCARGTNGCNACNAAYCAR GAYGGNGTNTTYGTNTAYGAYYTNGARGCNGARGCNAARCARTTYYTNTCNAARGGNGCN TCNATHGCNTAYGTNAAYTTYGTNAARATHYTNATGACNMGNTAYGCNGAYATHAARTCN TGYYTNAGYATGGAYAAYCCNGCNGTNGCNMGNTAYAAYCARGARTAYTAYGAYGGNGTN GAYGARATGMGNGARAARACNGAYCARGGNACNATHGAYTTYYTNYTNGARAARGTNCCN CARYTNAARGARAARYTNGARGCNGGNATHCAYGTNYTNGARTGYGGNTGYGGNMGNGCN TCNATHYTNTCNGCNYTNGCNYTNMGNTTYCCNGCNAGYACNTTYACNGCNAGYGARGTN MGNCCNCAYYTNGTNGAYAARYTNCARCARMGNYTNGGNCAYATHTCNAAYATGMGNTTY GARYTNYTNGAYYTNTGYGCNYTNCCNTGYCCNGTNCCNCARMGNTAYGAYTGGGTNTTY ACNAAYGAYGTNYTNCAYGAYYTNCCNCAYCCNGCNGTNGCNYTNAARGGNATHMGNCAR ATGGTNAARGGN---GAYGGNATHTGYACNTTYATHGAYCCNGCNGGNACNGGNAGYCAY ATHGARGAYTCNGGNGAYYTNGGNGCNGCNTGYYTNTAYTCNYTNAGYACNTTYYTNTGY GTNCCNGARAGYTTYCARAGYGCNGAYAGYGARGCNCAYGGNGCNTGYTGGGGNAARGAY ACNGCNYTNACNTTYATGMGNGAYGCNGGNTTYGAYACNTAYGTNGARCCNYTNAARGGN AARATGTGYYTNTTYATHGCNAARGAYGTNGARCCNCCNCCNGARTAYACNGARMGNACN AAYGTNGCNAGYGCNGGNACNACNCCNCCNGARTAYAAY---GCNTCNTCNTTYCARGAR CCNCCNCCNTCNTAYGAYTCNYTNTTYGGNMGNGTNAARCARGCNAARGCNGAYTCNTCN AGYCAYYTNGGNTTYTTYAARACNYTNTTYATHATHTTYTTYAGYACNATHGGNTTYACN ATHYTNATHGGNATHYTNYTNGCNATHCCNATHTCNATGATHGTNATGGGNGCNATHCAY YTNGAYGAYTGYCCNGCNGARMGNATGATHCCNATHTAYYTNYTNGTNGCNGGNTGYTTY GGNTGYGTNAARAAYYTNTTYAGYYTNTTYCARMGNTGYMGNAARTCNAARGARGARMGN GARGARGAYCARACNAARGTNCAYCCNYTNGCNAGYYTNYTNGAYTGYTTYYTNTTYGCN TGGTTYATHGCNGGNTGYGTNTTYATHTAYMGNACNAARGAYGAY------TTYCARTCN CAYGAYACNAAYGAYGAYTAYTGYGAYTAYACNYTNTAYTGGTAYGCNTTYTGGATHACN ACNTCNGTNTAYATHATHATGGGNGCNAGYTGYYTNTGYATHTGYGTNATHGGNTGYYTN GCNGCNTGY------------AGYCAYGTNATHTGYGGNTCNYTNAARAARACNGARAAR TTYATHGGNGCNTGYATHACNGGNAARTGGATHYTNACNCCNCAYTTYATHGARGAYAGY CAYGARATHGGNYTNTGGYTNGARGARGARAAYTAYYTNTTYAARGTNGARAAYAARGAY YTNYTNAARGAYCARYTNGCNCARTCNGCNMGNMGNTGGMGNYTNATHAAYGARACNGAY GARGGNCCNAARGAYGCNATHAARGCNTTYMGNAARMGNATHTCNCARAAYGTNGGNAAR AAYTAYACNACNGTNATGTAYTGYYTNACNTGYYTNGARGCNTGYGTNAARAAYTGYGGN MGNMGNTTYCAYYTNCARGTNTCNAAYAARGAYTTYYTNCAYGAYYTNATHAARATHATH GGNCCNAARAAYGAYCCNCCNCARATHGTNCARGARAARGTNYTNAGYATGATHCARACN TGGGCNGAYGCNTTYMGNGGNAAYCCNGARYTNAARGARATGGARAARGTNTAYCARGAR YTNAARCARAARGGNATHGARTTYCCNATGACNGAYYTNGAYAAYATGGCNCCNATHCAY ACNCCNGCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MGNTGYMGNCARTAY GAYGTNGTNGTNAARGARACNCARTGGCCNATHGTNTAYAGYGAYGARTAYAAYATHGGN TTYTGYGGNYTNGARAARYTNCAYCCNTTYGAYGCNGGNAARTGGGGNMGNATHTTYGCN TTYYTNAARGCNGCNGGNATGYTNMGNGARGAYACNGTNGTNGARCCNTTYGARGCNAAY GARGARGARYTNYTNTCNGTNCAYACNAARMGNTAYYTNAGYAGYYTNAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYGAR ATHAARCARYTNYTNTGGACNGCNAARGAYYTNAARACNMGNATHAARGAYAAYMGNGAR GTNTTYCARCCNYTNGTNGGNAARACNGCNGCNYTNATHTTYCARAARMGNAGYACNMGN ACNMGNYTNTCNACNGARYTNGGNYTNGCNMGNYTNGGNGGNCAYGCNGCNTTYATGGGN GCNGARGAYGTNCAYYTNGGNGTNAAYGARAGYACNAARGAYACNGCNMGNGTNYTNACN GGNATGGCNGAYGTNATHYTNGCNMGNGTNTAYGARCARGARTTYYTNCARACNYTNGCN GAYGARGCNTCNGTNCCNGTNATHAAYGGNYTNTCNGAYYTNYTNCAYCCNYTNCARATH YTNGCNGAYTTYATGACNYTNCARGARCAYTTYGGNTAYYTNCAYGGNTGYAARATHGCN TGGGTNGGNGAYGGNAAYAAYATHYTNCAYTCNYTNATGTAYGGNTGYGCNAARYTNGGN ATHGAYYTNGGNGTNGCNACNCCNACNGGNTAYGARCCNGAYCCNGAYATHGTNYTNGAY GCNATGAARATHGCNGGNAARACNGGNGCNTCNTTYAARATGGGNAAYAAYCCNYTNGAR GCNGTNTAYMGNGCNGAYGCNGTNATHACNGAYACNTGGATHAGYATGGGNCARGARGAR GARAAR---CARAARMGNATGGCNGAYTTYAARGGNTAYCARGTNAGYMGNAARATGATG AARGARGCNGGNGGNGARTGGGTNTTYYTNCAYTGYYTNCCNMGNAARCARGARGARGTN ACNGAYGAYGTNTTYTAYGGNCCNGARTCNYTNGTNTGGAARGARGCNGARAAYMGNATG TGGACNGTNATGTCNGTNATGYTNCAYCARYTNATGCCNTAYACNCCNACNAAYCCNATG CCNAARTAYGTNMGNGGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGTCNGAR---------------------------------GARTTY GAYGAYAAYATHAARGARGAYCAYYTNGARAARTTYAARAGYMGN--------------- ---------------------------------------------------GAY------ ---------------------------------CARGAYGAYCARGGNAGYMGNAARMGN MGNGGNGAY------ACNGAYGARGAYGAYATGAARGAYTGYGARGAYATGATHTCNAAR AAYGTNAAR------------------------GAYGCNGCNMGNMGNGAR--------- ---------CARACNYTNGTNATGMGNYTNACNAAYAARGARCARGARYTNCARGARTGY ATGAAYCARATHCARGARAAYACNGCNCARYTNMGNTCNATGYTNYTNGTNTTYCARMGN ATGTCNAARGARATGGAYGARCAYAARGARAARYTNAARCARAARCARAAYGARYTNAAY GCNTGGAARTTYACNCCN------------------------------GARTCNMGNGCN GARATHGCNAGYTCNGARGARTAYTGYAARTTYTCNTCNGTNMGNAAYCAYTCNYTNTCN GGNMGNGARGGNGAYGGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATHGTNCAYGAYAAYGAYGTNGAYTAYATHGTNATGCAR TTYGGNMGNGTNGCNGARGAYGTNTTYACNATGGAYTAYAAYTAYCCNYTNTGYGCNYTN CARGCNTTYGGNATHGCNYTNAGYAGYTTYGAYGGNAARYTNGCNTGYGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNTTYYTNTGYMGNGAY GAYGAYAGYYTNTAYYTNACNCAYCARAARATHCARATHYTNTCNAARATGATHACNATH GAYAAYGTNGAYCARATHTTYTCNGARTAYYTNGCNAGYGTNMGNACNATGGGNYTNAAR GARATGAARCAYYTNGTNCARAARGTNCCNGARGTNATGATHGARAARCCNGAYGTNTTY CARGCNTGYGTNGAYTTYYTNAARAAYYTNATHGCNACNGAYAARCCNGARATHATHAAY GARGTNGTNCARGTNYTNCCNTCNATHACNYTNGARGARGAYGAYCARTGGGARGARATH YTNACNATHGTNACNGAYAARTTYGCNTTYATHACNTCNYTNGAYGCNAARACNGCN--- ------------------------------AARACNAARAARGGNAARGGNGAYTCNAAR AAYYTNTCNCCNTCNAARGARAARGARYTNYTNGAYAAYATGCCNMGNATHGARMGNACN GAYCCNGTNCCNYTNGAYGAYACNGTNTAYTCNGTNTTYGARGARMGNCCNAARGARGCN GTNMGNGCNAARGCNAAYGCNGTNGCNNNNCAYAAYATHATGGCNACNAARAARACNGCN AAYTCNAARAARAARAAR------CARGAYGARCCNAARAARAARCCNAARCARGAYYTN GCNTAYGCNYTNTCNAARYTNGAYCCNAARCARYTNGARGGNGTNYTNGARCARTCNCAR TCNTAYTTYCCNAAYCAYCCNACNGTNTGGYTNAARGAYYTNGCNTCNTCNYTNAAYATH GARYTNGARAGYACNCAYGAYACNGAYCCNATHTAYAARGGNAARTCNGTNGGNTTYCCN YTNGAYGCNGTNACNCCNTCNTAYGCNAARGTNYTNCAYACNTTYATGAARAARTTYTCN CARCAYACNYTNGAYAGYATHTTYTCNTAYGGNATHCARGCNATGYTNCARGARTTYGAY AARGGNAAYCCNGTNCAYGGNTAYAARYTNTTYYTNCARYTNYTNTCNTAYACNAARCCN GAYATHGTNATGGAYAARYTNCCNCARTTYYTNGAYYTNYTNAARATGCAYCAYAAYAAY CCNACNAARTGYYTNTCNATHYTNTGGGCNYTNGGNCARTGYGGNTTYAARAAYTTYAAY TGYGGNATGAARGTNTGGYTNGAYYTNATGYTNCCNGCNYTNGARGTNMGNCARGTNGCN CAYTAYCCNGTNGARTAYYTNGARCAYYTNATHCAYTCNAARAARAGYGCNAAR---AAR ------------AGYTAYGGNYTNATHACNYTNMGNGARTAYTTYCARGTNYTNGAYGTN TTYTTYACNCCNCARTTYGCNYTNGCNAAYGAYYTNMGNAARMGNYTNACNATHTGYTAY CCNTTYATHAARAAYYTNGCNTAYGGNGARGARCCNTCNCAYAAYYTNMGNACNTTYTTY CCNTCNTAYYTNGCNMGNTAYACNTCNACNAAYTCNCARCCNYTNAARGCNGARYTNYTN GARTGYYTNACNCAYTGYYTNATHACNGAYAARCARTCNTTYAGYGCNTGGTGYCARYTN TAYACNAARCAYYTNAAYGCNTCNAGYCAYYTNYTNGAYTAYATHAAYCARCAYTGGAAY AARYTNTCNTCNAARTTYAAYAARAARGTNYTNACNGARACNYTNMGNTCNTTYTCNGTN ACNAAYGARGARYTNGARATHCARAGYAARGGNAARAARGAYGGNYTNAARYTNTGYCAR GCNGCNACNAARGAYYTNATGYTNAARYTNTCNGGNGCNCAYTTYCCNTGGAGYATHYTN ATGTTYTTYYTNGTNTCNGTNTTYGCNGCNATHGTNGTNTAYGAYATHATHTCNAGYCCN AGYTTYMGNATGTCNAARACNATGCARTTYYTNGARCAYTAYGGNATHYTNGCNYTNYTN GARAAYACNTAYCARTGYGTNCAYAAYGGNGCNACNYTNTCNATHAAYTGGYTNAARGTN AARTGYCCNATHTTYTAYGCNAAYGTNMGNGAYACNGTNGGNCCNTTYATGGTNYTNGTN TGGCARACNTCNMGNGAYTTYATHATHAAYGCNGARGTNATHTCNMGNCCNTAYMGNGCN AARATGGTNGARAARTGYATHCARYTNTAYTAYTGGGTNTAYGARYTNTCNCCNCARTTY TGGGTNAARTGYGGNGARTTYTCNTGGYTNGCNTGGGARATGYTNAARGAYTAYTCNATH MGNATHTGGAARCAYGTNYTNYTNTAYTCNGGNGARGCNGTNGAYTGGGTNACNGARAAY GTNGTNAARGGNTCNTGGTCNAARCARTCNATHAARGAYACNGCNATGTGGGGNGTNGAR CAYYTNCARAAYTGYACNTCNTTYYTNGTNTCNTGG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYACNYTNCARGTNGAYGARAAYMGN CARTAYGTNGTNTCNGAYTGYAARCCNAGYATHCCNGAYGTNGARGARATHGTNCARGCN YTNAAYGCNGAYAARGAYTTYCAYAARTTYATGCAYACNATGMGNMGNAARTTYAARCAR GGNAARGGNGGNGARGCNACNYTNAARGARTTYCARGAYAARTTYGGNGTNGAYAAYGTN AGYTTYTAYGTNTTYGAYATHACNGAYYTNGAYAARTAYGARGAYGCNTTYAAYMGNGCN GTNTCNAARTTYGGNCCNATGGAYATHATGATHAAYAAYGCNGGNATHATGCAYGARGGN GCNTGGGARAARATGATHGARATHAAYGTNACNGCNGTNGTNAARGGNGTNAARYTNGCN GARTCNGTNATGMGNAARGAYAARGGNGGNAARGGNGGNMGNATHATHAAYATHAGYTCN TGYGTNGCNYTNTGGTCNTCNTGYTAYGTNCCNATHTAYGCNGCNACNAARCAYGCNGTN MGNGCNTAYACNTCNAGYCARGCNATHCARMGNGAYYTNGARGCNCARGGNATHGARTAY GCNCARYTNTGYCCNGAYCCNGTNGAYACNGARATGGTNMGNGGNATHGAYTCNGCNAAR ATHAARTTYTAYGAYYTNATHAARGARAGYTTYAARGAY---ACNATHCCNCCNCARMGN TGYGTNGARGCNYTNYTNCARYTNYTNAGYYTNGARAARATGAAYGGNGCNATGYTNTAY GTNMGNAARMGNMGNTAYAGYGAYGTNYTNGAR---GAYCCNTAYAARGGNCCNAARGAR TTYATGGARGCNGGNGTNMGNGGNTTYYTNGTNACNTCNGTNCCNGAYMGNGARGARCAY GCNYTNGAYGARGCNGTNAARTCNYTNMGNAARTCNTGYATHAARYTNTAYGGNGGNATH MGNCCNYTNMGNMGNGARGAYGCNTCNTTYGCNAARGGNTAYGTNATGGTNGAYTTYATG GAYCCNGARGCNGTNATHCCNATHCCNCAYCCNGAYGCNGAYAARTTYGCNGCNGARGCN AARGARAARGARAARGARGCNGARCCNACNGARGGNGGNAARGARAARGARACN------ ---------------------------------------------------GARGCNATG GARGARGARACNAARGAYAARGTNGTNGARGARGARCCNGARAARGARAARGCNGAYCAR GARGAY---------------GARAARGTNGARAGYAARGARGARGARTCNGARTCNAAR GGNGARGARAARAGYGARGAYAARGGNGARGGNGARAARGTNAARGARGARAAR------ AGYAARGARGARAARACNGAYCARAARAARAARGARGARMGNAARAARAARAARGARGAR GARGARAARGCNAARCCNCCNYTNATGYTNGCNCCNCAYAARTTYCARAGYTTYMGNACN GARYTNMGNAAYATHATGTTYATHAARGCNGAYGTNGCNGAYCCNGCNATHGTNGCNACN ACNGCNTTYGAYYTNATHATGGARMGNAARCCNYTNYTNACNGAYTGYATHAAYCARYTN YTNCCNGTNCARGGNGTNTGYGAYAAYGAYTAYAARCARYTNGARATHATGTGYMGNMGN GTNYTNACNCCNTAYTTYGGNGARCAYYTNGARGARCCNCCNAGYTTYGGNGTNATGYTN GTNGAYAARATGTCNGARCCNGGNGCNGARGTNYTNYTNGARGTNATHMGNAGYGCNATH TGGTGYYTNGAYCCNAAYGCNTAYCARTGYTCNCCNTGGTCNGARCCNGAYATHGTNATH CAYGTNGARATHATHGGNAGYAARATHATHYTNAGYGCNATGAARCAYTAYATGAARTAY MGNCARTAYAGYCCNTTYGCNTGYCAYGARATGGGNGARGGNAARCCNGARGAYGARGAY ------AGYATHYTNAARGARAARCARGARGARAARGAYAARGAYMGNAAYMGNGAYAAR GAYAARGAYAGYMGNMGNAARAARMGNGAYMGNGAYAAYAARGGNAGYAARGAYGGNTCN CAYAAYAARAARAARGARGCNGARAAYAARGARAARCCNATHAARAARCCNGARGARAAR GARAAYYTNGAYAARGAYGARAARAARGARACNGARACNACNGARGARACNGARACNAAR GARGARGCNAARGAYGGNAGYGARAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TTYGARTCNYTNYTNYTNGARCARGCNCCNGCNYTNATHGCNMGNAAYYTNATH YTNGARCARGAYGGNTCNYTNCCNGCNTTYYTNTTYAARGAYATGCAYGGNTCNAGYGCN TGGYTNMGNCAYMGNGTN------AAYTTYGAYGARATGTTYCCNTCNTCNCARAGYTCN GAYTGYAARTCNGARTTYGGNCARTAYATGGARYTNGARTTYGGNGGNGAYGCNTAYAGY MGNATHAARTCNTCNTCNTCNGCNCCNTCNATHTCNYTNYTNCAYMGNAGYYTNTCNGTN GAYAGYCARTGYGCNMGNGAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GTNAARATG CAYMGNGAYATGAAYAAYYTNAGYGTNATGTGGGAYGCNGAYMGNAARGAYTGGGARGAR GTNGARAARYTNYTNCAYACNCAYAGYGGNAARYTNMGNAGYYTNYTNATHTCNTAYCAY GTNYTNGGNMGNATHCCNCAYATHGTNTTYGTNAARGAYAARACNAAR---ACNAAYYTN ACNCARYTNTCNGARYTNTTYGCNCARGCNGAYTAYGGNCCNGAYTAYYTNCCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GCNCARMGNTGGTTYCCNCCNYTNCCNMGNGAYTGGGARGCNMGNTTY GAYCCNAGYCARAAYMGNTAYTTYTTYATGAAYCAYAARACNMGNGCNACNCARTGGGAR GAYCCNMGNTTYCCNACNAGYACNGCNTCNTCNGCNGCNGCNGCNTCN------------ ------------ACNGCNCARAGYTAYCARGARYTNAGYTCNCCNTCNMGNACNGCNGCN GCNCARGCNATHYTNGARAARYTNCAYAARGARTTYCCNAARGCNAGYAARGARATHATH GCNGAYATGYTNTCNAGYTGYTAYAAYAAYGARMGNCARACNMGNGARCAYYTNACNAGY ATHGGNTTY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNATGGARGGNCAYATHYTNAARTTYACNAAYGTN GTNAARGGNTAYCARTAYMGNTGGYTNGTNYTNTAYCCNGAYTCNGGNATGYTNGARTAY TTYGARAARGARGARCAYAARAARCARMGNCCNMGNGGNTCNGTNCAYYTNGCNGCNGCN GTNGTNTCNCCNTCNGARGARGAYTCNCARACNTTYATHGTNAGYGCNGCNAAYGGNGAR ATHTAYAARYTNMGNGCNTCNGAYGCNMGNGARMGNCARYTNTGGGTNGAYMGNATHMGN TCNACNGCNGARCAYCAYACNGCNAAYATHGCNCARCAYTCNCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATHAARAARATH GCNCCNAARAAYGARAARGARTGGGARTGGYTNGTNAARYTNMGNAGYCCNCARGAYYTN YTNAARCAYCAYGARACNTTYYTNTAYTGYGARATHATHTTYTAYATHYTNGCNTTYYTN ACNTTYATHCAYGCNGTNMGNAGYGGNGGNMGNTAYAARTGGYTNTGGTTYGCNACNATH GCNCAYGGNYTNACNGTNGARAGYATHTCNTAYYTNGTNCCNGAYATHGAYAAYTTYTGG CAYGCNCARTCNATGGTNACNYTNYTNGGNCARMGNYTNCCNYTNCAYATHYTNTTYGTN TAYCCNGCNTTYATHTAYACNGCNACNGTNGCNGTNTCNCAYYTNAAYYTNAARTGGTGG GCNGARCCNYTNGCNATHGGNYTNTCNGTNGTNYTNATHGAYATHCCNTTYGAYATHATG GGNATHAARYTNYTNTTYTGGACNTGGCAYGAYGAYGAYCCNAAYATHTTYGAYMGNCAY TAYTGGGTNCCNTGGACNTCNTAYTAYTTYCAYGCNTCNTTYGCNTCNTCNTTYGCNTTY ATHTTYTTYGGNGCNAARAARYTNTTYTGYTGYMGNGGNCCNAARTTYCARAGYAAYGGN TTYTTYATHGARYTNYTNGTNYTNGTNATHACNGGNYTNTTYTCNATGCCNGTNGGNGTN YTNCARTTYGTNCCNATHTAYCAYCCNYTNCAYGAYAGYTTYGGNYTNCAYTCNGARGTN TGYGTNYTNYTNTTYYTNGGNTTYTAYGCNYTNATGGTNTGGAGYTCNGAYMGNMGNCCN TCNGARYTNGCNMGNCAYAARGGNGGNAGYATGTTYAGYYTNATGATGYTNACNYTNYTN ATHCAYTAYGGNTTYTAYGTNTAYYTNGTNTTYACNGCNGAYCCNACNGCNATHAARGCN ATHGGNYTNCAYCARCCNGTNGGNCCNTGYGAYAARCCNGTNMGNGTNYTNACNCCNTTY GGNCAYATHYTNAARAARAAYGARAAYYTNTGYGTNAARAAYTAYTCNGARGAYTAYTTY ACNYTNGAYTGYYTNAARAARGCNCCNGCNAAYGGNACNAGYTGGTAYACNGTNTGYGGN ACNCCNTAYCCNAAYATHATGGARTAYMGNATHGTNGTNAGYGCNTTYTGYGCNYTNGGN YTNTTYTGGTTYTAYCARGCNYTNTGYMGNTCNGGNATGCARCCNAARATHCARGCNTCN AAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TTYGGNATHTAYYTNACNGARACNGTNAARATHGCNAARATHTAYATHGCNATHYTN CCNYTNTTYACNTAYYTNGCNAGYTTYGTNACNTCNATHYTNGCNCCNTTYATHAAYAAR YTNYTNGGNMGNAARYTNACNTAYYTNGTNGGNTTYYTNTTYGGNGTNGGNTCNTGYACN TGGYTNTAYTTYATH--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY CAYGCNGAYGAYGARGAYYTNCCNCCNGGNGTNMGNAARCARAAYMGNTGYCAYAGYAGY GGNACNGARGAYTCNGARGAYGARCARTCNAARGGNGGNGAYGAYAAYTCNTCNGAYTCN GAYTCNGAYAARTCNGTNAARAARGAYGAYGARACNAAYGAYAARYTNTCNCCNMGNGCN CAR---AARTCNATGTCNCCNTGYAARGARAARGGNTCNTCNAARGCNAARCARAGYMGN TCNMGNTCNGAYTCNMGNTCNMGNTCNCAYTCNMGNTCNAARAARMGNMGNTCNTCNGAR AARAGYMGNMGNTCNMGNTCNMGNTCNYTNGAYMGNMGNCAYAARAARGAYMGNMGNMGN MGNTCNCAYMGNTCNMGNTCNMGNGAYMGNMGNMGNTCNMGNGARMGN---CAYAARCAY AARMGNGAYMGNMGNAGYAARAGYMGNAGYAARAGYMGNGAYMGNAARAARMGNMGNMGN GARMGNAARMGNMGNAGYMGNAGYMGNAGYMGNMGNAGYMGNAGYMGNAGYMGN---MGN AGYMGNAGYMGNAGYMGNAGYMGNAGYMGNGARMGNAARAARGAYAGYMGNAGYTCNAGY CCNCAYGAYGGNAARATHATHAARTTYGGNGAYAARGTNATHAARGCNGGNGCNAGYTTY GGNMGNCCN------TCNGGNAAYTTYTCNAARCCNYTNACNTTYAARGARAARATGMGN CARCARYTNATHAARGCNATHGARGAYGGNGCNGAYACNAAYGAYGTNYTNGCNCAYAAR GGNGGNTCNACNATHTGYACNCARAGYGCNGGN---GTNGCNCAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGCNCCNATHCCNGARGAYAAYCAR GARMGNCCNCCNCCNGAY---GAYAAYGCNGAYYTNTCNGCNCAYTCNAAYCCNAAYYTN GTNACNGAYYTNGAYTCNGAYTTYAGYGAYGAYGAYAAYGAYAAYGAYAAYTAYCCNGAY GCNACNGGNTAYGTNYTNYTNCCNCARGARCCNGGNGARAAYGAYGCNGAYAGYGAYGAR GARMGNGAYATHGARTCNTAYCCNAAYATHGARGGNTCNCARGAYAAYCAYGAYTGYGGN GGNGTNGGNGGNTCNACNGTNTCNAAYAGYAAYATHACNCARAARGTNGAR---YTNAAY GGNTGYGARGCNGGNGTNTCNTCNTCNGCNCARGCNGARGTNCCNGTNTCNYTNCAYCAY GARTTYYTNGAYAARTCNCCNGARGGNAARTCNCCNGCNTAYATGCARATGCCNAARYTN CCNGCNAGYAAYAARGAYTCNYTNTGGAAYAARAARMGN---GTNGARAARAAYACNGCN YTNAAYTCNGCNCARGARAGYAARATHYTNAAYGCNATGTCNGGNTTYTCNATHCCNTCN GARAAYATHCCNGAYTGGGCNMGNAAYATGTCNCARGARCARTGGGAYYTNACNGTNAAR AARATHAAYAARCCNGAYGAR--------------------------------------- ------------------------------------GTNYTNCCNTGYTCNTCNTTYYTN ATHGAYGGN---TTYAAYCCNCCNATHMGNATHGCNGCNTTYAAYATHMGNCAYTTYGGN MGNTCNYTNATGGAYAAYGAYGTNGTNGTNGGNCAYYTNCARAARGTNATHGGNMGNTAY GAYATHGTNYTNGTNCARGARACNMGNGAYAGYACNGGNACNGCNYTNCCNGAYYTNGCN AARACNYTNAGYTCNGCNGGNCAYACNTGGMGNTTYGTNGCNAGYTCNCCNYTNGGNMGN ACNCARTAYTAYCARGARCARTAYGCNTTYYTNTAYACNGAYAAYGTNCARTTYGTNAGY TCNCAYCARGTNAAYGAYACNGAY---GCNGAYYTNTAYGARMGNGARCCNTTYGCNGCN GARTTYCARTAYAGYTCNGGNACN------------AARAAYGTNGTNYTNYTNGCNTTY CAYTCNAARCCNACNAARACNAARGARGARYTNCARCAYYTNCCNGAYACNATHAARGCN GTNGCNGGNYTNTAYCCNMGNGCNGCNGGNGTNATHACNATGGGNGAYATGAAYGCNGAY TGYGAYTAYYTNACNGGNAARTGGMGNTCNTCNYTNGARATHTTYAAYGGNGAY---CAR TTYMGNAGYYTNATHCCNGARTCNGCNGAYTCNGCN---GTNTCNGAYMGNGAYTGYGCN TAYGAYMGNATHATHGTNCAYGGNAARGGNGTNGAYGCNMGNGAYGCNAARGTNTTYGAY TTYCARACNCAYYTNAARYTNTCNCARGCNGARGCNYTNCARGTNAGYGAYCAYTTYCCN GTNGARTTYTCNYTNTAYMGNTTYAGYYTNAAYYTNTGYGTNGGNCCNACNTAYGAYCAR GAYTGYGCNYTNCAYTTYAAYCCNMGNTTYGAYGAYAARMGNGTNGTNMGNAAYCAYATG CARGGNGGNGCNTGGGGNCARGARGARACNGCNGGNGGNTTYCCNTTYCAYAARAGYATG GTNTTYCAYYTNGARATGGARGTNCAYCAYCAYGGNTAYMGNATHACNGTNAAYCAYAAR MGNTTYTGYGAYTTYAAYCAYMGNYTNCCNAARGARAGYGTNCARTTYATHTAYATHGAR GGNGARGTNGTNATHAAYAAYATHCAYTTYACNGGNACNCCNCAYCAYGGNCCNAGYGCN CCNCCNTCNTAYCCNACNGGNCCNGTNGCNCCNCCNAGYTTYCCNCCNGCNCCNTCNTAY CCNCCNAAYCCNGGNTAYCCNGCNGTN------------CCNGGNGGNGGNTAYCCNGGN GTNCCNAGYGGNCCNATHTAYAGYCCNCCNGTNCCNTTYACNAGYCCNATHCCNGGNGGN YTNTAYCCNGGNAARYTNATHTAYATHACNGGNGTNCCNCAYCCNAAYCCNAGYMGNTTY ACNATHAAYATGCARTGYGGNCCNTAYGAYTCNGGNGAYYTNGCNATGCAYTTYGAYATH MGNTTYAAYTAYGGNAGYGAYMGNAAYCARGTNATHMGNACNCAYMGNCARGGNGGNAAY TGGGGNCARGARGARAARGGNGTNTCNCAYTTYCCNTTYTAYCCNAAYGCNACNTTYGAR ATGATGGTNYTNACNGARCCNTCNGGNTTYAARATHGCNGTNAAYAAYCARCAYTTYGTN GARTTYTTYCAYMGNYTNCARCCNTTYAAYMGNGCNGAYCAYATHAAYATHGTNGGNGAY GTNACNYTNACNCARGTNMGNTTYCARACNAAYTCNTTYGTNCCNAAYTTYYTNGTNAGY TCNGGNTCNGGNYTNACNCCNACNYTNACNCCNACNACNYTNGCNACNATHGARCARTCN TTYATGGARATHCARCARACNGGNGCNMGNGAYCCNGTNACNCARAGYGGNTTYGTNCCN CCNGTNATHGARCCNTCNAAYAGYAAYAGYGCNGAYCARTCNCARGAYAGYTTYGAR--- TCNTCNTCNGAYCCNGARTGGGARCCNAGYGCNAARAAR---YTNATGAARGAYGGNGTN AARGGNGTNGAYTAYATHGTNACNTCNACNGGNACNGTNAAYGTNACNCCNCARMGNAAR TAYACNMGNMGNAAYAARGAYGARAAR--------------------------------- ---------------AARMGNCARATHGGNAARCARAAYYTNTCNTCNTGGYTNCARAAR ATHGGNAARATHMGNMGN---AARATGAAYACNGARTCNAARGARAARCAYACNAGYATH AARATHAAYGAYTAYYTNTGYAARYTNCAYCAYTCNATGAGYYTNATHGGNAARATGTCN AARCARGTNGARAARYTNGARTCNATGATHTCNGAYACNGAYMGNTCNTCNTGGCARAAR GARTCNGAYGCNTTYGARGCNTTYAARACNGARNNNAARAAYYTNGARAGYGGNATGGAR AARTCNAAYGTNAAYGARGTNAARMGNCARYTNACNMGNYTNAARTCNAARMGNGTNMGN ATGAARAARTCNTAYCARMGNAARCAYCARCARAARCARGARACNGARGARGCNMGNGCN GTNMGNGARAARGARATHTCNGAYTGGCARCARAARYTNMGNTCNGARATGAARGARGAR YTNYTNAARAARAARMGNAARCARGARATGGAYCARACNYTNAGYACNGTNACNAARAAY ATHCARGAYGCNAAYMGNYTNATHGARACNATGAARGCNYTNGARAARYTNMGNYTNATH MGNCARGAYGCNGCNAARAARMGNGGNGAYGCNGAYYTNGGNGARTCNMGNCARAGYTTY GARCARAARATHGCNGAYATGACNMGNYTNGTNGARTCNCARYTNGARGTNTAYAARGAR GARGARCARACNYTNMGNGGNGCNYTNAARTCNGARCARGAYGARYTNAGYAARAARGAR AARCARATHCARGARMGNAARGAYGARGARGAYCARMGNCARAARGARGARGAYYTNMGN AARACNYTNTTYGGN------------------GAYYTNYTNGAYGARGTNGARTCNAAR TAYGTNAARAARCCNCARGARCARCCNAARCCNAARGCNYTNCCNAARCARMGNAAYACN GTN---------------------GAYGCNGCNATHAAYGAYATHYTNGAYYTNGAYATH GAYGAYCAYYTNCCNGCNCARAARGTNAARTCNAAYAGYGAYGTNTCNAARGTNTCNTCN CCN------MGNGARMGNAARGARGCNGCNAARAARTGYTTYCCNGTNTTYYTNGGNGGN AGYAARGAYGARGCNGGNYTNGGNACNACNGTNAARACNMGNGCNTGYGAYCARYTNMGN TGYACNTCNTGYGAYTTYMGNATHTGYTTYTTYGAYGAYTTYTCNTGGAARAARGAYACN AAYTAYYTNTTYYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TGYGGNCCNGCNCCNCCNAGYYTNYTNGAYMGNMGNAARYTNGTNGTN CCNGARCCNMGNCCNGCNGTNYTNGGNCCNGCNMGNACNACNGTNCCNGTNCCNTCNGAR CCNGTNCCNGTNCAYCCNGGNGARCARGARATH---------AARAARCAYTCNATGATH AGYTAYCARGGNCCNGAYGGNTCNATHAAYAAYAARYTNCCNGCNTAYAAYAAYGGNGGN ------ACNGGNCAYMGNGTNAAYATHTAYCCNACNAAYCAYGGNGARGTNAAYTAYTAY MGNGAYCAYAAYAGYCCNCAYGGNCCNAAYGARCCNTAYATGCCNTCNCCNGGNTAYGAY AARGARGCNCCNAARTAYCARTCNTCNMGNCCNGTNAAY--------------------- ------------------------------------------------------------ ---------------------------------GTNTAYTGYCCNTAYGAYCCNAGYCAY GTNTTYCCNGCNAARGGNYTNAAYGCNCAYYTNATHMGNTGYMGNCARAAYAAYAARCAY GTNAARAARGTNACNTGYCCNTTYGAYAGYACNCAYATHATHCCNGGNCCNGARATGAAR CAYCAYYTNGCNCAYTGYACNAARMGNTCNYTNYTNGAYMGNGARYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GCNGCNGGNGCNAAYTCNCAYTAYGTNYTNYTNCCNGARGTNCCN CCNGAYACNGCNGARACNAAYTCNYTNATGMGNATHGAYCARYTNCCNGARTTYACNYTN ATHAGYCCNGAYCAYTGYGTNACNGGNTGYGCNAARYTNACNATHGARTAYGARACNAAR YTNGARAARCAYATHGARACNYTNAARGAYGTNAARGCNGARAARACNTTYGARAGYGTN TAYCAYCCNATHGARGARATHAGYGTNCCNYTNAAYACNGCNTGGGCNACNGTNAARAAY YTNAAYTAYATH------GCNGAYGAYTAYMGNACNGCNTTYTCNAARATHCAYCCNCAY GTNGARMGNGTNAARAAYGARMGNTGGGTNAGYGARACNYTNTAYTAYTCNTTYAARGAR YTNGARTCNAAYAGYGGNAAYYTNACNGAYTAYCARAARMGNYTNGTNAARYTNTAYYTN YTNGARGGNAARYTNAAYGGNGTNCAYYTNTCNGCNGARGARAGYTCNAARYTNGTNGAY MGNYTNAARGTNATHACNAARGARGGNCARAAYTTYMGNAAYAARGTNMGNATHTGYACN GAYATHTTYACNCAYGAYGTNGTNAAYTTYAAYATGATHGARGARATGCCNTGGCCNYTN YTNGCNCARATGTCNACNGAYMGNTCNAAYCCNACNMGNGGNCCNTGGMGNGCNACNYTN CARCCNGCNGTNTAYCARGCNATGATGACNTAYTGYAGYCAYMGNATGACNMGNTGGAAY YTNTGGAAYGCNTAYCAYAAYMGNGCNTCNCAYYTNCAYGCNGGNCARTAYYTNAAYAAY AAYAARYTNATHGARAGYYTNMGNGCNTAYMGNGCNGAYGTNGCNGGNATGYTNGGNTAY GAYAAYTTYGCNGARATGTCNATGGARACNAARATGGCNGAYTCNGTNGARACNGTNYTN AGYATGATHGARACNYTNMGNACNMGNTTYGCNCCNGCNGTNTGGGARGARACNGCNCAR YTNCARGARTTYGCNACNTCNGARGGNTTYGARCAYTCNYTNGARATGTGGGAYATHGGN TAYTGGMGNMGNMGNCARMGNGARCAYYTNTAYAGYGTNGAYAARGARGCNATHMGNGAR TAYTTYCCNGTNAAYTCNGTNYTNYTNGGNYTNTTYGAYYTNTGYACNTCNYTNTTYGGN GTNAAYTTYGARGARGTNACNCCNGAYGTNGAYGTNTGGCAYCCNGAYGTNMGNTTYTTY AAYATHYTNGAYGAR---GAYGGNACNCAYATHAGYTCNTTYTAYTTYGAYGCNTTYGAY MGNCCNGGNAARYTNTCNTCNGGNTAYATGGAYYTNGGNMGNGAYAAYAGYGARYTNTGY GGNACNTGGCCNTAYTCNTAYYTNTGYYTNAARGTNCCNMGNCCNMGN---CARTCNGAR CCNGCNYTNATGMGNTTYGARGAYGTNGARATGYTNTTYACNGARTTYGGNCAYGGNYTN CARCARATGYTNACNMGNGTNCCNTAYAGYGARATHGCNGGNCARAARAAYATHGARTGG GAYGCNGTNCAYGTNTGYGCNAARTTYATGAARMGNTGGYTNACNGTNCCNTCNGTNGTN AARAGYYTNAGYGGNCAYTAYAGYTCNGGNCARCCNATHCCNGAYGAYGTNYTNGAYACN ATGYTNAARGCNTCNCARCAYTGGAGYAAYTTYGAYATGATGTAYCARYTNTAYGTNTCN GCNTTYGAYATGGARATGTAYACNACNAARAAYCAYTGGTAYAGYGTNATGCAYCARYTN TGGGARAAYTTYGTNCCNYTNCCNYTNTCNAARGARGAYAAYYTNCCNTGYTCNATGYTN CCNYTNTTYTGYGARYTNTAYCCNGCNGCNTAYTAYTCNCAYAARTGGTCNGARATGATH GCNGCNGAYYTNTTYTCNGCNTTYGARGARGTNGGNYTNGAYAAYCARGARAARATHAAR GARGTNGGNAARMGNTTYMGNGAYACNTAYYTNGCNCARGGNGGNGGNGTNCCNTCNAGY GARGTNTTYMGNCARTTYMGNGGNMGNGAYCCNTCNACNCARGCNYTNCARCCNATGGAR AAYAAYAAYGCNATHGCNGCNAAR---GCNATGGARGGNGARGCNAARATHGARAAYGTN AARCCNACNGCNGARGAYAAYGAYTCNTCNCCNGCNTCNMGNMGNTAYAAYAAYMGNMGN MGNCARCARTAYMGNMGNGAYGTNAAYCCNGARGAYGARACNGGNAARGCNGCNATHMGN MGNAARATHTGGGAYCAYYTNGARGAYAAYAAYYTNGTNTCNACNCCNMGNCCNTGYCAY TAYMGNATHCCNAAYTTYGARGGNGCNGCNGAYGCNGCNAAYMGNYTNACNTCNYTNGAR GARTTYAARAARGCNMGNACNATHAARGTNAAYCCNGAYAARGCNCARGARCARGCNMGN TAYYTNGTNYTNGARGARGARAARGARYTNTTYYTNYTNAAYCARAAYCARAARGAYYTN ATGGTNCCNACNCCNGARYTNAARTCNGGNYTNYTNAAYMGNGTNATGCCNCCNGARGGN GCNAAYAARGARGARATHMGNCAYTGYTGYACNACNCARGGNGTNAARGARAAYAGYCAR GARATHGCNYTNGAYAAYAARATHAARYTNGAYYTNATHATHGTNGGNAGYGTNGCNGTN TCNMGNAAYGGNTTYMGNATHGGNAARGGNAARGGNTAYGCNGAYYTNGARTAYGCNATG ATGMGNACNATGGGNGCNGCNGAYGCNAAYACNGTNGTNGTNACNTCNGTNCAYGAYTCN CARGTNGTNGAYATHACNGARGAYYTNGTNGAYGARCAYGAYATHACNGTNGAYTAYATH YTNACNCCNACNGARYTNATHAARACNAAYTGYACNMGNTCNMGNCCNTCNGGNGTNGTN TGGAAYCAYYTNGARGTNAAYAARTTYTAYCARATHCCNGTNYTNMGNCARYTNMGNAAR AAYGARMGNGARAAYGGNAARGARGTNYTNYTNAARGARCARAARGARGARGAYGARGAY CCNGTNGAYACNATGGARCCNCCNMGNCCNMGNMGNTAYGTNMGNTAYTAYCARAAYGCN GGNGGNTTYMGNGGNMGNGGNGGNCCNTAYMGNGGN---GGNMGNGGNGGNGGNGGNGGN MGNMGNMGNATGGAYAAYGGNGAYGARAGYAAYAARGARAAYATGGAYGGNGGNGARGAY TCNGGNGCNGAYGGNGAYAAYGARGGNMGNGGNCCNMGNMGNAAY--------------- AAYTTYMGNAAYMGNMGNTTYCAYMGNGGNGGNGGNGGNCCNGGN---MGNGTNTCNGAR TCNGARCAYAGYGAYGGNGGNGGNATGGAYGGNCARGAYGAYGGNGARGAYMGNCCNAAY MGNMGNMGNTTYAAY---AAYCCNAAYAAYAAY------------CCNMGNMGNMGNMGN TTYGGNGGNAAYMGN------MGNGAYAAYMGNAGYTCNGCNGAYGTNTCNGGNAGYGAY GGNGARCARAARAAYTCNGCNGAYGARGAYGGNGAYGGNMGNMGNCCNCARMGNCARMGN TTYMGNACNAAYCCNGARGCNGTNGTNTTYGTNGGNGCNYTNGCNMGNAAYYTNMGNGTN AGYGARYTNAARACNGARYTNMGNAGYCAYAAYGTNAAYCCNGTNMGNYTNYTNTGGMGN GGNGGNMGNGGNTAYGCNTTYYTNTTYTTYACNGGNACNGAYAAYGCNAARGARGCNGTN GAYGTNYTNACNGGNMGNGARYTNAAYGGNMGNGARATGAARGTNGARATGGCNAAYATG GAYMGNGARTCNMGNMGNMGN------------------------------AARCARATG GGNTCNATHGCNTTYGAYMGNCCNACNGTNYTNMGNGARACNGTNCARTTYTAYYTNCAR TAYAARCAYTAYTGGAGYAGYCAYGAYTAYGAYMGNATHTCNAAYYTNGTNGTNGARYTN TTYCCNGARTTYAARGAYGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGCCNGTNGARAARGTNACNGAYAAYTCNGGNMGNAGYYTN TTYYTNGTNCCNTTYCAR---------GAYTTYTTYYTNTCNCCNCARTTYAAYGARGAR GCNGTNAARCARTCNMGNGARTTYCCNYTNMGNGAYGAYGAYGTNATGYTNGTNAGYTAY CCNAARTCNGGNTGYCAYTGGGCNTGGGARATHYTNMGNATHYTNGTNACNGGNAGYGTN CCNAAYAAYGGNATGGAYAARACNGCNTAYATGATGGARTGGAAY---CCNCARCARGAY TTYGARACNYTNCCNTCNCCNMGNGTNYTNAAYAAYCAYYTNCCNTTYMGNYTNCARCCN GCNGAYYTNYTNACNAARYTNCCNMGNGTNGTNTTYTTYTAYMGNAAYTTYAARGAYGTN GCNGTNTCNTTYTTYCAYCAYCAYGTNGGNATHAARGAYTAYGGNTAYCARGGNGAYGAY TTYGGNGCNTAYYTNCARMGNYTNGTNGCNGGNCARGTNGARTCNGGNAAYCCNTTYAAR TTYACNMGNGARTGGGARGARGGNATGGCNGCNCAYCCNCARYTNCCNGTNTAYTGYTGY GCNTAYGARACNATGAARGAR--------------------------------------- ------------------------------------------------------------ ------------AAYCCNATGGARGARATGMGNMGNYTNTGYAARTTYYTNGGNAARGAR MGNGAYGARGCNTTYYTNCARGARGCNTGYAAYGCN---------------GTNAGYTTY AARACNATGAARCARACNYTNGGNGCNACNAARCCNGTNTTYTAYMGNAARGGNCARGTN GGNGAYTGGMGNAAYCAYTTYTCNGARGCNCARAGYGCNTGGTTYGAYGARYTNATHAAR TCNGARATGCCNAAYTCNAARYTNGARTTYMGNTAYTCNYTN------------------ ------------------------------------------------------------ ---------------------------GTNTAYGAYCCNGTNTTYTCNYTNCARGARCAR GARATGYTNGARGAYYTNGGNTGYTCNYTNATHGGNCAYAAYGARGARGGNAARCAYGTN TGYAAYYTNCCNACNGTNATHTTYATGCCNCAYTGYGGNAARGCNYTNTAYAAYAAYYTN YTNTGGGCNAAYYTNGCNACNYTNGGNAAYYTNGTNYTNYTNGGNAAYAGYTTYTCNTCN ATGATHGAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GCNYTNTGGAARGAYGTNTGYMGNTTYGTNTCNAARGGN CARTTYGTNCCNGTNGGNGGNACNTGGGTNGARATGGAYGGNAAYATHCCNTCNGGNGAR GCNTGYATHMGNCARTTYYTNTAYGGNCARAARTTYTTYMGNGARGARTTYGGNATHCAR TGYAARGARTTYTGGYTNCCNGAYACNTTYGGNTAYTCNGGNCARTTYCCNCARATHYTN MGNCAYTGYGGNGTNACNMGNTTYYTNTCNCARAARYTNAGYTGGAGYYTNGTNAAYAAR TTYCCNCAYAAYACNTTYYTNTGGGARGGNATHGAYGGNAGYACNGTNYTNTCNCAYTTY CCNTCNGGNGAYTCNTAYGARATGTCNGGNMGNGTNAARGARYTNMGNAARTCNGTNAAY AAYTTYMGNGAYAARGGNMGNTCNAAYMGNTCNGCNTTYYTNTTYGGNCAYGGNGAYGGN GGNCAYGGNCCNAGYGARGARATGYTNGGNMGNYTNTTYMGNTTYAARGAYTGYGAYGGN YTNCCNAARGTNAARTTYAGYGGNTCNGAYGARTTYTTYNNNTCNATHGARAARGARGGN ACNGAYATGYTNTGYMGNTGGMGNGGNGARYTNTAYYTNGARYTNCAYAAYGGNACNTAY ACNACNTGGGCNCARGTNAARAARTGYAAYMGNCARAGYGARGTNYTNYTNCARGCNATH GARGCNYTNTCNACNATHGCNTGYYTNMGNAAYAARGARTTYMGNTAYCCNTAYGGNGAR YTNGARMGNYTNTGGAARYTNYTNYTNYTNAAYCARTTYCAYGAYGTNYTNCCNGGNTCN TCNATHTCNCARGTNTTYACNGAYGCNATHGARTAYTAYAARGAYATHGAYTCNTCNGGN CARAARYTNYTNCARTCNGCNYTNACNGCNAGYGTNACNGGNTCNCARAARACNGAYACN ACNACNAARGGNGGNYTNTAYGTNATGAAYGTNCARGGNTTYGARATGYTNACNGTNTGY ACNYTNCCNAGYAARTCNMGNGARCCNGCNGARCCNGCNGCNAARATGMGNMGNMGNAAY TCNGTNAAYYTNYTNAARGTNCCNCCNYTNTGYACNAARCCNATHGARGAYTGYATHGTN YTNCCNGTNAARTGYATHMGNCARGGNGCNAAYTTYATHYTNCARAAYGARTGGATHAGY GCNGARGTNGAYCCNYTNGGNMGNGTNYTNTCNYTNMGNTGYATGGAYGCNGTNTGYGGN ACNYTNGGNMGNGARGCNATHGCNTCNGCNTAYCCNGCNAAYCARTTYGTNYTNTAYGAY GAYATHCCNYTNTTYTGGGAYGCNTGGGAYGTNATGGAYTAYCAYYTNGARACNMGNCAR CCNYTNTCNCARCAYGTNAARGTNGARGARGARAGY---CCNATGMGNGTNACNYTNTCN GTNAGYATHCARATHAGYGARGARAGYTGYATHAARCARMGNATHATHYTNGCNTCNGCN AGYCCNYTNYTNMGNTTYGARACNGARGTNGTNTGGAARGARAAYMGNMGNTTYYTNAAR GTNGARTTYCCNACNTCNATHCAYGCNACNGARGTNACNTAYGAYATHCARAGYGGNTAY ATHCARMGNCCNAAYCAYTTYAAYACNTCNTGGGAYTCNGCNAARTTYGARGTNTGYGGN CAYAARTGGGCNGAYATHTCNGARCAYGGNTTYGGNGTNAGYGTNYTNAAYGAYTGYAAR TAYGGNTAYTCNGCNGTNGAYGGNGTNATHMGNYTNTCNYTNYTNYTNTCNCCNAARGGN CCNGAYCCNAAYGCNGAYATGGGNACNCAYACNTTYGCNTAYGCNYTNATGCCNCAYGTN GGNACNTTYCARGAYGCNGGNGTNATHCARCARGCNGTNAGYTTYAAYAGYGGNYTNMGN ATHYTNCAYGCNGARGGNACNCAYTGYGCNCARAGYGCNGCNTCNTCNTAYCCNYTNTTY MGNTCNATHACNCCNCARGTNTTYGTNCARACNGTNAARATGAGYGARGAYCARAARTCN GCNGTNATHYTNMGNYTNAAYGARGCNTTYGGNGGNMGNACNMGNGCNGARATHTGGTCN AGYCARCARTTYTCNGCNGTNCARATHAGYAAYGGNYTNGARGAYGARAAYGARGARGAR GARAARAGYYTNGARYTNAARACNGARMGNATHGAYACNGGNYTNAARATHTCNGCNTCN YTNAARCCNTTYCARATHGTNACNYTNMGNTGYTGYYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GTN AARTTYAARCARAARGGNGARGCNACNCCNCCNGARGARYTNTGYGCNGTNTGYYTNGAY GARTTYCAYCCNAAYCARAARATHMGNATHYTNCCNTGYTGYCAYYTNTAYCAYACNMGN TGYGTNGAYCCNTGGYTNGTNCAYAAYMGNACNTGYCCNYTNTGYAARYTNGAYATHYTN GAYAGYMGNGCNGARGCNAAYYTNGCNYTNTCNGTNAARACNTCNTAYTCNTAYCARGAR YTNTAYCARGCNACNAAYAGYTTYAGYCCNGARAGYATHYTNGGNGARGGNGGNTTYGGN GTNGTNTAYCAYGGNCAYYTNMGNGGNATGGAYTGYGCNGTNAARAARTTYTCNAARAAR AARGCNGARGGNAARGARAAYTCNGAYCARATHAAYAGYGARYTNTCNGCNYTNYTNAAR TAYCARCAYGARAAYATHGTNACNYTNTAYGGNTAYGCNTCNGAYGGNCCNGARYTNTGY YTNGTNTAYCARTTYYTNAGYAAYGGNTCNYTNGARGAYMGNYTNYTNMGNAARAAYAAY ACNCCNCCNYTNACNTGGGARMGNMGNYTNAAYATHYTNGTNGGNTCNTGYMGNGCNGTN AARTTYYTNCAYTCNATGGGNTCNCARCCNYTNATHCAYGGNGAYATHAARAGYGCNAAY ATHYTNYTNGAYCARCAYMGNGARGCNAARYTNGCNGAYYTNGGNCARTCNMGNTAYGCN ACNAGYMGNAGYGCNAAYACNGGNAGYGTNACNCAYATHACNYTNGCNGARAGYACNCAR MGNCARTAYGGNACNGTNGCNTAYCARAGYCCNGARGTNAARACNGGN------TGYAGY ATHTCNGTNCARTCNGAYGTNTTYGCNATGGGNGTNGTNYTNYTNGARGTNTGYAGYGGN YTNCARGCNTAYGAYCCNAAYMGNMGNGAYAAYAARTTYYTNACNGAYYTNTAYAGYCAR AAYATHGCNMGNMGNACNGAYACNGARCARMGNCARATG---TTYGARGAYAARAGYCCN TGYGAYMGNYTNGARCCNGCNGTNTTYATHTCNYTNATHAARYTNGCNGGNAARTGYGTN AARGAYAGYAARAARAAYMGNCCNACNAGYACNAARYTNYTNAARGGNGTNGARGARYTN TAYCCNACNYTNAARTTYYTNAARGARACNTAYGGNAAYAARYTNAARATHACNAARAAY AAYGTNAGYYTNCARYTNAGYAARAAYAAYCAYYTNACNGGNGTNACNAGYATHGCNAAR AAYGTNCARMGN------GARTTYTAYAAYGGNYTNAGYYTNGARGAYMGNATGGCNGTN GARCARTGGATHGAYTAYAGYTGYGAYYTNTCNGCN------------TAYGARAAYGCN GGNGAYMGNGARAARGTNTTYAAYATHATGAARGAYYTNAAYAGYTAYYTNGARGAYAAR GTNTAYTTYGTNGGNTCNGAYYTNACNGTNGCNGAYGTNGTNYTNTGYCAYAAYYTNTAY TCNACNTTYACNAARYTNACNATHCAYGARAARGARMGNYTNATHCAYYTNTCNMGNTGG TTYAAYCAYGTNCARTAYGAYGCNMGNGCNAARCARTGYTTYYTNCCNGTNAARTTYYTN MGNACNYTNATHTAYGCNGGNGTNGGNAAYCAY--------------------------- ------------------------------------------------------------ ---------------------------AGYAARYTNATGYTNACNAAYGAYYTNACNCCN GCNGTNATGGARGARGCNMGNGAYAARACNGTNGAYYTNATHGTNTCNTAYCAYCCNCCN ATHTTYGTNCCNATGAARMGNTTYACNCARAARTCNTGGAARGARMGNATHYTNATHGAR TGYATGGARAGYMGNATHGCNGTNTTYTCNCCNCAYACNTCNTAYGAYGCNGTNCARAAY GGNGTNAAYGAYTGGYTNATHTCNGCNTTYGAYATHGAYAARGARACNYTNGARCCNGTN GARGTNACNAARGCNTTYGTNAAYAAYAAYACNCAYGTNYTNGARGTNGAYYTNGARCCN TCNAAYYTNAAYGARGCNTGGAARGCNGTN---ACNACNTTYYTNTCNGARAAYTCNTCN ATHTGGAARCAYAARACNCCNTAYTCNACNAGYGTNATHAARACNGGNTCNAARGARCAR TGGMGNYTNMGNYTNGARTGYAGYCARTCNGAYYTNYTNGAYYTNATGAARGGNGTNATG TCNTGYCARATGGTNGARAARTAYTCNATHTCNTCNYTNTCNCARGTNCCNCARYTNAAR TGYGGNATGGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGGAYYTNYTNMGNTCNTGG YTNTAYGGNMGNGAYGAYYTNAARAGYATHGARATHGARCARAAYGARACNATHTTYCAR AAYYTNGCNTCNGARGGNMGNATGACNGARAAYAARTCN------------------TCN AARTTYYTNAARTAYATHCCNYTNCARCCNGGNGAYTGYYTNGGNTGYAARYTNGTNGGN ACNTCNGTNATGATHGTNAGYGGNTTYATHGTNYTNTCNTCNGCNATHGCNGGNAARAAR MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ACNTCNGGNMGNTCNCCNYTNATHGCNCAYTAYYTNCAY ATGMGNCARYTNMGNAGYTAYAARCARCCNGGNATGAARGTNMGNMGNACNGARATHYTN AARYTNCCNCCNGAYGGNCCNACNTAYCARCARTTYATHTCNAAYACNGTNAAYAARGCN GARTCNYTNGARMGNGARTAYACNMGNATHTGYGAYCARACNTCNTCNGCNATHYTNGAR YTNGARMGNTAYAARMGNGAYTCNAAYMGNGARATHAAYGARYTNAARAARGCNYTNACN AAYGTNAARAGYATHCCNGARMGNMGNYTNYTNATGGARAARATHTCNGARTAYAARGAY YTNATHATHAARGARMGNCCNYTNYTNGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AAYTTYTTYACNYTN CCNCAYCCNGCNYTNGGNGCNYTNATGYTNTGYGCNTCNGCNTAYYTNATHGTNACNACN GTNTCNCCNAAYAGYYTNCCNGAYTTYYTNTGGCCNTTYGCNCARATHGGNAARTAYATG GGNAAYCARCAYTTYAAYGTNTGYATHGGNTTYTGYTGYTTYACNYTNATHGCNCAYTCN ACNGARGCNGCNTAYGCNGGNAARGTNTGYCAYGAYMGNMGNTAYACNATGTCNACNACN TTYAARTGGGCNYTNTCNACNTTYATHTTYGGNTTYCCNTCNYTNYTNMGNYTNATHCCN CAYAARCCNMGNTCNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGYGGNGGNCAYATHGTN ATHGTNCCNTGYTCNMGNATHGGNCAYGTNTTYCAYAARTGGAAYCCNTAYYTNAARGAR GARAAR---ACNTAYATGAARAAYAARYTNMGNYTNGTNAAYGTNTGGYTNGAYGAYTAY AARAARTGYTAYTTYCAYGARAAYCCNAARGCNYTNAAYGTNGAYTAYGGNGAYATHAGY GARMGNGTNMGNYTNMGNGARAARYTNAAYTGYACNTCNTTYCAYCARTAYYTNAARMGN GTNTAYCCNGARAARYTNGAYAAYYTNCCNYTNCAYTGYTCNGAYGCNYTNGARAAYGTN GAYGCNAARAARAARAARYTNTCNMGNAARCCNYTNGTNACNTCNAGYGGNYTNYTNTGG CAYMGNYTNTCNGGNYTNTGYGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GGNAARTTYGAYCCNTGGMGNYTNATGGARGARATHTCNGARGAR ATHYTNTCNGAYTGYYTNCARGARGTNTCNGARGARGTNGARAARGTNAGYGARGARATH GCNAAYCARATGTAYMGNTCNGARTTYGTNGTNACNGGNMGNCCNTCNGARACNTTYGAY GAYGAYGAYGAYGAYAGYYTNTAYGGNGAYCAYYTNTCNAAYAGYTGYTTYGCNTCNYTN MGNATGGAYMGNMGNGAYAGYGAYGAYTTYGAYGAYGAYYTNMGNTCNYTNGARTGGYTN CARAGYGARGAYYTNYTNAARAAYATHGGNGGNGARAARYTNGAYMGNGAYGAYTGYGGN GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNGGNAGYGGNCAYACNGCN YTNTCNYTNTCNATHGCNTAYGGNAAYGARTAYTTYGCNCCNYTNTTYGTNTTYAARTCN GAYGTNAAYACNCARGAYAGYGAYAARGAYACNCCNATHATGTTYGCNGCNTGGAAYAAR YTNCCNMGNGTNATGAARATGYTNATHCARTAYGGNGCNAAYGTNAAYGCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CARATGACNGTNTAYTCNGCNGAY ACNYTNTCNAARTCNGGNYTNTTYGTNCCNAGYGCNGTNMGNTAYGCNAARCAYGCNGTN TCNACNYTNGGNCAYTCNYTNCAYACNACNGGNTAYTTYCCNCAYACNATHYTNYTNTGG ATHTCNMGNAAYYTNCCNYTNTCNATHTGGATGTGGGGNTCNGARATHTTYCAYAAYTCN YTNMGNMGNCARGCNYTNAARMGN------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AAYCARATH GCNGAYGGNTGYATHGGNAARGTNATGGAYATHTTYTTYYTNYTNGAYTCNTCNTCNTCN ATHTAYATHAAYGAYTAYATGTCNCARCAYMGNGTNGTNMGNGAYATHGTNACNAARTTY GAYGTNAGYCCNGARGCNACNMGNGTNGGNATGYTNACNTTYAGYGAYGAYYTNGARMGN CCNGTNATHGGNYTNAAYMGNTAYGCNAAYAARGAYGARYTNYTNTCNGARATHTCNATG CARAAYYTNCCNTAYMGNACNGGNGTNACNAAYACNGAYYTNGCNATHMGNTAYGTNMGN CARYTNAGYGAYTTYMGNCARGAYATHACNAARGTNYTNGTNGTNATGACNGAYGGNGGN TCNMGNTCNCCNGGNGCNACNGCNMGNGARGCNGARGCNGCNMGNGCNGCNGGNTTYTAY YTNTAYGCNGTNGGNATHGGNCARTAYYTNGARGARMGNGARTGGMGNTCNATHGCNAGY GAYCCNGAYTCNAGYTTYATHTAYAAYATHTCNAGYCCNMGNATGYTNGARGARGTNAAR TTYTCNYTNCCNCCNMGNGCNTGYGCNYTNCCNCCNATHATHYTNGGNGGNTCNTGYGAY ATHTCNMGNCCNTCNGARGTNTAYTTYGTNTCNGCNMGNAGYGCNAGYGAYAARGCNATH GARYTNATHGAYACNTTYAARMGNMGNACNMGNGAYGTNMGNGAYAAYYTNMGNGTNAAY TAYATGATHGARGCNTGYGGNTCNGTNAGYAAYGCNGCNYTNGAYGAYGARGAYGTNAAY ---TGYGAYMGNTTYGGNCCNAARACNGGNGAYACNGCNGARTCNGTNTCNGCNYTNYTN TCNMGNGTNMGNGARATGGCNMGNCARGAYGARGCNGGNAAYAGYGCNAAYMGNGTNGTN GTNYTNTTYACNGAYGAYTCNACNATGAGYYTNGCNMGNTTYTCNTGGGCNAAYGARGCN MGNGCNATGGARTCNTTYGARGGNTTYACNGTNGTNGTNGCNAGYYTNGAYGTNMGNACN TAYMGNGAYTTYGAYMGNMGNYTNACNGGNAAYMGNAAYAAYTAYGTNTAYTTYGCNCCN GGNTCNGTNGGNAAYCARTAYAAYGCNCARMGNCARTTYYTNGAYGCNGTNTGYGCNGGN ATGGCNGAYAAYAGY------CCNGAYYTNYTNTTYGAYAGYCARCCNGARAGYTCNGGN TTYTCNAAYGAYGAYTTYGARAARYTNGAYGCNCCNGGNGGNGGNTTYGGNCAYGAY--- GAYGTNACNGCNGCNTCNGGNGCNTAYGAYCAYGAYGTNAAYCARGAYGCNGARATHTCN ACNACNACNGAYACNGAYGTNGCNGGNGARGARGARGCNGARGCNGAYMGNTTYGCNATG GGNTCNCAYGARGARYTNGGNCAYCCNTCN---------GAYCCNYTNATHTCNTGGGGN GAYGARGARGARGARGAYAAR------------------------------GTNACNTCN CARGTNCARCCNTCNGCNCCNGTN------CCNGAYAAYATHGARCCNYTNGTNAAYTTY ---GAYGAYAGYATHTCNGGNGAYGAY---TAYYTNCARTCNTTYATHCCNTCNGTNCCN CCNACNAGYACNACNCCNGARCCN---ATHCCNGAYGCNTTYATHGARCCNAARGGNGAR GARAGYGARGARAGYGARCCNGTNGTNGTNGARGARGARAGYGARCCNGTNGTNGTNGAR GARAGYGARCCNGTNTCNGARACNGTNGARGCNGCNGARGGNTCNTGGYTNAARGGNGTN GAYCCNMGN---------------------------------GTNATHGAYYTNATHTAY TGGMGNGARGTNAARACNACNGGNYTNGTNTTYGGNGGNATGYTNGTNGTNYTNYTNTCN YTNGCNATHTTYTCNYTNATGAGYGTNYTNGCNTAYYTNTCNYTNGCNYTNYTNACNGTN ACNTTYAGYTTYACNGTNTAYAARAARATHATGGGNGCNGTNCARAARTCNAGYGAYGGN CAYCCNTTYAARCARYTNATHAGYATGGAYATHACNYTNAGYGARGAYAARYTNAARAGY GTNATHCARAGYGTNYTNAARAAYGCNAAYTGYACNGCNAGYGARYTNMGNMGNYTNTTY YTNATHGARGAYATGGTNGAYTCNATHAARTTYGGNYTNYTNYTNTGGGTNYTNACNTAY GTNGGNGCNTGGTTYAAYGGNATGACNYTNGTNATHYTNGCNGTNATHTCNYTNTTYACN YTNCCNAARGTNTAYGARACNTAYAARGTNCARATHGAYAAYTAYATHGGNYTNGCNAAR GCNCARGTNGAYAAYGTNATGAAYATHGTNCARACNAARYTNCCNTTYYTNAARAGYAAR GARAARGCNCAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYTTYACNMGNGGNTCNMGNGGNAAR GAYAAYTCNMGNACNATGYTNTGYCCNYTNATGGARAARTGGACNAAYGTNAAYGTNGCN YTNTAYCAYACNCCNGAYYTNMGNGGNYTNYTNAARAARGTNATGCCNGARMGNTTYAAY GARACNATHGGNYTNACNCAYYTNAARGTNTAYYTNTTYGAYAAYAGYYTNATHATHAGY GGNGCNAAYYTNAGYCAYGAYTAYTTYACNAAYMGNCARGAYMGNTAYATHYTNTTYAAY GAYTGYCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TCNGTNGARAAYMGNTGYCARYTNATG CARAARCARYTNGAYTAYATGGARAARYTNGTNAARAAYTCNGARGARGAYMGNMGNCAY YTNGTNGARAARACNYTNAARGCNMGNCARGAR------------CCNGAYATHAARYTN CARYTNAAYMGNATHAAYGARYTNGARMGNGAYCARYTNMGNYTNAAYGCNACNCARAAY YTNGCNGARYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TCNGAYTCNGCNYTNTCNCCNTCNTCNAAYYTNCARGCNTCNAAYMGNAARMGNGGNATH GGNMGNGTNMGNGGNMGNCAYGAYGAYCCNGGNGGNCCNACNATHTCNTCNTCNTCN--- ---------TCNGCNCCNAARTCNTCNTCNYTNGCNAARCCNTCNGCNTCNTCNACNTCN ACNACNCARCCNAGYTCNTCNMGNCCNTCNCARAGYTGYTCNGARGTNTCNGGN------ ---MGNACNTCNTAYAARCCNGTNGGNGAYAARTCNGGNAARYTNTCNGCNTAYGAYTTY CCNGAYGAYAGYCCNGAYGARGAYCCNGTNAAYTAYATGGCNYTN---GCNGGNMGNGCN GCNMGNAARTGYCCNGTNGAYAGYTCNGARAAYAARTCNGCNTCNTGGGTNGGNCCNGAY ACNCARGGNGCNGAYGARGGNAARGGNGARAARAAYGARGCNCARACNYTNGAYTCNTCN TAYCCN---------------------GARGGNAARCCNAARCCNMGNTTYGGNAGYMGN GTNAGYAGYGTNGARGCNGAY------GCNGGNATGTCNTCNGCNGAYAGYAGYACNMGN CCNGAYAARYTNTCN------GAYATGGGNGARGTNGAYAGYTCNACNTCNTCNTCNCCN GCNAAYMGN------------GTNCCNTCNGGNCARGGNTCNGARGCNAGYCCNGGNGAR TTYACNACN---------GCNGGN------------------------------------ ------------------------------------------------------------ ---GGNCARCCNGTNGTNTCNAGYATGYTNMGNGAYCCNGAYCARACNACNATGTGYTCN MGNGAYCARGARCCNGCNCCNYTNYTNTCNGCNCARTAYGARACNYTNTCNGAYGAYGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGTGGMGN TCNCARACNATHMGNAARGGNMGNGARATHYTNTCNYTNGCNMGNMGNCARTTYGCNGCN GARGCNGARGCNGGNGGNGTNCCN---------CCNCCNCARCARCCNAARTCNMGNAGY TTYGGNYTNGTNAARTTYTTYGGNYTNGGNYTNCCNYTNGCNGCNGGNGGNGTNGTNGGN TAYGCNTGGTAYGAYAAYGARTTYMGNAARCARYTNGARGAYAAYGTNCCNTAYGCNAAR GARGCNYTNGARAAYGTNYTNCCNCCNYTNGARGTNCCNGCNCARMGNGAYGTNTCNAAR GARGTNAARAARYTNCCNGCNAARAAYGAYCARTCNTTYCCNCCNCCNYTNYTNGARTCN AARCCNCCNCCNACNATGCCNTCNCCNCCNAAYCCNGTNACNCCNGARGCNTCNGCNACN GTNCARCARCARAARGARGARGARGTNAARGTNGARAARYTNACNATHGARCARYTNMGN AAR---AARGARGTNGARGARAARGARGAYAAYGCNGCNYTNCARGTNGTNGTNGARAAR YTNYTNGARTCNGGNCAYAAYTGGGTNACNGARGCNGCNAARGCNCARCAYGAYGTNGCN AARGCNATHAARAGYCAYAGYGARYTNYTNAARAARGCNATGGAYGAYACNTCNGAYGTN YTNCAYAARGAYGCNGARTGGGARGCNGTNACNATGGCNTTYAARGARMGNGARACNGCN ATGGCNMGNGCNAAYGARYTNGTNGAYGARGCNAARGGNTGYATGGTNAARYTNAARAAR GTNYTNGARGARGCNAARGCNAAYAARGTNACNAARAARAAYGCNTCNATHTTYCCNGCN ACNAARAARYTNTCNGARTTYGAYAARGARYTNTCNGCNGCNGGNTCNCARGTNMGNCAR GCNGAYGCNGAYGCNAARGTNATGYTNAARTTYAARGAYYTNGTNGAYAARGGNAARMGN CARTTYCARYTNGARYTNGARAGYYTNATGCCNGAYGTNMGNCCNGGNAGYAARAGYMGN AARYTNTCNGARGARGARYTNAAYGCNYTNATHGCNCAYGCNCAYMGNMGNATHGARCAR YTNCARAARCARATHGCNGARCARYTNGCNYTNGARMGNAARMGNYTNGCNGTNGCNYTN GAYYTNCARCARGGNGARAAYAARACNGTNACNCARGCNGCNGTNYTNGAYGARCARAGY MGNYTNYTNAAYGARTTYGARATHGARAARCARAARYTNGARGTNGARTTYYTNGCNMGN ATGGARGCNGAYGTNMGNAARCARYTNAGYMGNCARGCNGCNGCNCAYAGYGAYCAYYTN AARGAYGTNYTNGCNGTNCARGARGARGARYTNAGYAARGAYTTYGARMGNAARATGAAY ATGAARYTNYTNGARGARMGNGAYAARTTYCARTCNGARACNTGYGGNTGGATHTCNMGN YTNAARGGNATHGARGCNGCNGTNGAYGCNMGNGCNGCNAGYGARAARYTNGCNMGNCAR GCNCARGAYYTNTGGYTNGCNTGYATHTCNYTNAAYTCNACNATHYTNTTYGGNAAYGAR GARGARATHGARACNYTNYTNCCNYTNCARGCNCARGTNGARTCNGTNATHAAYTCNGCN AAYAARCAYCCNTTYGTNGARACNATHGCNAAYAGYATHCCNGARGCNGCNATHAARMGN GGNGTNTAYACNGARAGYGARYTNMGNAAYMGNTTYGCNAARGTNTCNCARGTNAGYAAR MGNYTNGGNYTNGTNGGNGARCCNGGNGCNTCNYTNTAYAARTAYYTNGTNTCNTTYYTN CAYTCNTTYTTYACNGTNMGNAAYGTNGCNGCNCAYTCNGARAARGAYYTNGTNTCNYTN GARGAYATGGAYAAYTTYGARYTNGTNGCNAAYGCNCAYTAYTGGATGGARMGNGGNAAY YTNGARATGGCNYTNMGNTTYATGACNCARYTNAARGGNGARTCNMGNAAYGCNGCNGAY GAYTGGATHACNGARGTNMGNYTNYTNYTNGARACNMGNCARGCNGCNCAYACNATHACN GCNTTYGCNTCNGCNACNGGNYTNGCNGCNACNTTYGARGAYYTNAAYYTNATHGARYTN YTNTGGAARCARGAYGTNGAYYTNGGNGTNGGNAARGARGTNTAYGAYCARTCNYTNMGN GARGARYTNGARMGNCARMGNCARYTNGARCARTAYAARCARCARGARAARYTNAARGCN CARGTNGCNGCNAARGARAARGARGARAARAGYAARYTNGARGARGCNAGYMGNTGGYTN AARCARAAYTTYATGMGNGAYGGNGARACNGGNGARTGGGTNAARYTNCARAAYAARAGY CCNTCNAGYAGYAARGGNCAYGGNTCNGGNGCNACNGTNGARGARGARAAYGARGAYTCN YTNACNYTNGARGCNGCNYTNGAYTAYATHTCNTGYAGYATGGAYCCNAAYTAYTTYACN GCNACNGARGARGTNGCNYTNCCNGARTCNTTYACNAGYGARYTNACNCCNTTYCCNTCN GGNYTNGAYACNAAYGAYCARGCNATGCARCCNAAYCARCARGTNGARGGNYTNCCNGTN YTNACNGARATGTTYTCNACNGCNGGNAGYAGYAGYAGY------------AAYYTNGAR AARGARTGGACNGARGTNGARGARTAYYTNAAYATHTCNYTNACNAAYCCNMGNCCNCCN CARCARTCNCCNTCNGAY---------------GAYTCNGTNTGYAAYTCNAGYCCNAAR ATGGTNGGNGARGGNGARATGYTNCCNTCNCCNYTNGAY---ACNGARYTNCCNAARATH GTNGAYCARGGNYTNTTYACNAGYGCNGAYYTNCCNYTNYTNCARGAYGCNTCNYTNCCN TCNGCNGARATGGARCCNGTNTCNGAR---------YTNAGYGTNGGNGCNCARACNAAY AGYAGYYTNCCNCCNGCNCCNTGYGCN------ATGAAYACNTCNYTNGAYTGGGGNYTN GAYAAYYTNAAYTTYTTYGAYAAYYTNACNGCNYTNTCNGARGGNAAYATGGAYGAYYTN GAYYTNCAYAAYATGGARGGNYTNTTYAAYACNATGACNGARGCNTCNGARYTNTCNGCN ATHAAYACNTCNGAYATHAAYGGNYTN--------------------------------- ------------ATGGTNCCNGGNAGYYTNAAYGARAGYTCNGCNYTNTTYAAYACNACN TCNYTNTCNGGNGAYYTNAGYGAYGCNTTYGAYGGNYTNGARGGNGCNACNGGNGGNAGY GAYTTYAGYGCNCARGAYAAYYTNGAYTCNGAYCCNTGYAARAARATHTCNMGNYTNTCN GARTCNTCNTCNGAYTCNGGNTTYGGNGGNAARGGNGGNTTYAGYCCNTCNTCNTCNTCN ---TCNTCNTCNTCNTCNTAYGCNGGNAGYCCNGCNCCNTCNACNTAYACNAAYTCNACN ---AAYTCNAAYGAYACNGARCAYGAYCCNGAYGGNACNMGNGTNYTNGCNCAYCARGTN GCNCAYAAYCAYACNTAYAAYACNYTNCCNGGNCAYGTNCCNMGNGARGTNAARAARTAY GCNCCNAARGARAAYTCNMGNAARGGNCCNCARTGYMGNGAYGARAARMGNGCNAARGAR YTNAGYATHCCNTTYAGYGTNGAYGARATHGTNGARTCNCCNGTNGARACNTTYAAYGAY ATGYTNACNAARTAYAGYYTNAAYGARGAYCARYTNACNYTNGTNMGNGAYATHMGNMGN MGNGGNAARAAYAARYTNGCNGCNCARAAYTGYMGNAARMGNAARGTNGGNGTNATHGTN AAYYTNTCNGAYGARATGTCNGARYTNGARAARGCNMGNGAYMGNYTNAARGCNGARMGN GCNGARATGGARMGNGARACNMGNAARATGAARGARAARTTYGGNCAYYTNTAYTCNGAY ATHTTYCARTCNYTNMGNGAYGARCAYGGNCARCCNTAYGAYCCNAAYYTNTAYTCNYTN CARCARTCNAGYGAYGGNAAYGTNTTYYTNGTNCCNMGNAAYGTNAGYACNAAYGGNAAY GGNTCNGGNACNAGYAGYTCNGGNAGYGGNACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CCNYTNTTYATHTTYTCNGAYGTNCCNTTYGAYACNYTNTCNYTN GTNTAYYTNACNGGNGGNTGGGTNMGNATHTAYTTYACNMGNACNACNAGYTGGYTNACN GCNATGATHTCNYTNGARMGNTGYATGTGYATHATGATHCCNYTNAARGTNAARTCNATH GTNACNMGNAARMGNTCNATHTAYACNATHGTNACNATHTTYATHAGYATGTCNTTYACN ATGCCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGTTYAAYAARGTNGCNCCNYTN YTNMGNGTNGTNCCNMGNGTNMGNAAYACNMGNAGYATG---GGNGGN---GGNGTNCCN GCNCAYTGGAARCCNATHMGNCARGTNTGYGARGARAAYAARAGYCAYATGAAYTGYATG CCNATHCCNGARGGNTCNTGGCARGAYGCNTAYAAYGCNAARAGYGCNAARTAYAAYACN YTNYTNATHGCNAGYYTNGGNAGYYTNGTNGCNACNTTYACNATGYTNTAYGCNACNGGN TGYATHTAYYTNCAYGGNCCNCCNCCN------------------------------ATH AARATHCCNCCNAARTTYAGYAARYTNGTNGCNGARAAYTAYAGYYTNAGYGARAARTGY TCNACNACNAARYTNGTNAARAARATGCCNCAYGARGAYGCNGCNGARGCNTTYGTNGAY MGNYTN---YTNAGYCARAAYACNGTNAGYGARGARYTNTTYGCNMGNGCNAARGCNATG TCNTGYYTNCARAGYCAYAGYYTNATGTGGGAYATHYTNCARTCNYTNGARGTNGARAAY YTNTCNGARACNACNCCNTTYGARACNATHTAYMGNGCNCARAARYTNGTNGARTTYGTN YTNTCNATHTTYTCNGARGCNCARGAYGARGCNGAYTAYTTYTCNAARGTNCARTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNGTNAGYTCNYTNMGNGCNACNYTNGARGAR GCNAARAAYAARATHGAYAARYTNMGNGAYGAYAAYGAYMGNAARGAYGAYATHATHGAR GAYGARMGNAGYMGNMGNYTNGARYTNGARGARAARATGGARAARTAYYTNGTNGAYYTN TAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------TAYAGYCAYGARTGGGARMGNTGYYTNGTNAARTGYTCNCARATGYTNATG GARGCNAAYACNYTNTTYAAYAGYATHAGYAGYTCNGCNATHTGYAAYGARGTNYTNAAR TCNTCNCARGGNTGGGAYTAYGTNGCNTGYGTNATHGARATHTAYMGNGTNGGNTGYMGN GTNATGGCNACNATGMGNTCNACNGCNATHTCNAGYAAYGARYTNGARCARACNYTNAAR GARATHGAYYTNATGTGGAAYAAYYTNTCNGCNTTYYTNGTNGGNGCNTCNYTNYTNCCN GAYCCNTCNTCNYTNYTNTTYACNGAYGCNGTNYTNAARTCNGGNCARGAYAGYAARCCN TCNTCNGCNTGYGGNGTNTGYYTNYTNAAYGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AAYMGNGCNGTNTTYYTNTGGACNATGGCN GARAARAARGARAARCCNMGNYTNAAYGGNCAYCAYAAYGARGTNGTNAGYTGYAGYTTY AGYCCNGAYTCNGCNATHYTNGCNACNGCNGCNTTYGAYACNAARATHATHYTNTGGAAY ATGGAYACNTTYAARCARATGMGNGTNYTNGGNCAYYTNTTYCCNAGYCCNAGYYTNATH TTYGCNGGNGGNGCNAAYGAYCAYTAYGTNMGNAGYGTNTCNTTYTCNCCNAAYTCNTCN ATHYTNGGNTCNGTNTGYGAYGAYAGYTAYATHMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNAAYYTNGGNGTNAARAGYAGYTCNYTNGCNCCNACNGCNTGYAARYTN TCNACNCARTAYYTNGTNYTNGAYCAYATGACNAAYCAYTAYAAYAARACNTCNAARGCN AARTCNGCNATHGAYAAYAARCCNCCNAARAGYATGACNACNAGYCARAARATGMGNGAY MGNAARACNMGNGARMGNGTNACNTCNCCNCAYMGNACNMGNCCNGTNTCNAGYATGTCN CAYACNTTYGTNGARGGNATGGARGARTAYCARGARYTNYTNGAYGARGARCCNGARGAY GARGARGGNMGNYTNGTNCAYTCNATHATGAARTCNACNYTNGGNMGNAARTCNAAYMGN AGYAAYGARGCNACNTTYAAYTCNAARACNCARACN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNGTNMGNCCNYTNAARGAR GAYGARTGYGGNCARATHYTNCARATGATH------------------------------ ---GTNGARYTNGCNGAYTTYGARAARAARGCNCAYAARGTNAAYYTNACNGCNCARGAY YTNAARCARGAYATHTTYGGNCARCCNGCNMGNTGYTGYTGYYTNGTNGCNGARAARCAY AARGAYCARGGNCARAAYYTNGTNGGNTAYGCNYTNTAYTAYGCNGCNTAYTCNACNTGG GARMGNATGTTYTAYCAYYTNGARGAYYTNTAYGTNAARCCNGAYTTYMGNCARAARGGN ATHGGNAARAGYYTNTAYCARGCNGCNGTNAARGTNGCNATHGAYGARGGNTGYCARMGN TTYGARYTNGAYGTNYTNGAYTGGAAYAARCCNGCNMGNGAYTTYTAYYTNAARATHGGN AAYGTNGAYATGACNGARGARGARGGNTGGCAY--------------------------- ---------------TCNAGYTCNTCNTCNTTYYTNTCNMGNAAYMGNGARYTNGAYTCN CCNMGNGGNACNAAYTCNAAYTCNGTNTTYACNATGAAYAAYCCNCARGCNACNTCNACN GGNAGYTCNCCNGGNYTNGARAAYGCNMGNCCNGTNGGNTTYTCNGCNTTYAARGAYTCN TCNGGNTAYTTYTCNAGYMGNTTYMGNGAYMGNGAYGGNGAYMGNTCNGGNGGNGTNGGN GCNGARCCNGTNCAYTCNMGNGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TCNGGNATHGCN GCNYTNGARMGNGARCARATHACNMGNCCNAARCCNATGGAYGTNGARGGNCAYYTNYTN CAYCARCCNTCNATHMGNCAYCAYCCNCCNACNAAYGARGTNYTNTCNAGYGARCAYTTY AARATGGAYCCNGTNGTNYTNCAYACNATHMGNYTNYTNCARCAYATGAARAARGTNMGN GCNGCNATHGARACNYTNCARCARGAYATHAARTCNGARAGYGARCCNAGYGCNGTNAAY GTNGGNCCNATHCCNGARTAYGAYGGNCCNCARATHAARGAYMGNTCNCAYCARAARTAY TTYACNGARGARGARTAYGARAGYAAYTTYGTNAARGGNGTNGCNAARCCNMGNCCNGCN ATHGAYGARATHACNTGYMGNAARYTNYTNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CCNGCNGGNCARTCNCARGAYGTNGARGGNGAR TGGTTYGARAGYTCNGGNTTYCCNYTNGARMGNMGNAARATHATHGAYGGNGCNGTNTCN TTYMGNCCNYTNGCNYTNCCNGARGAYAAYYTNCARCCNYTNCCNTAYTGGAARCAYGGN ATHAARGTNYTNCAYATHCARGGNAGYGAYGAYCARTGYTTYGAYCCNGARGTNYTNMGN AGYAGYCAYGCNAAYTTYGTNCCNGARTTYAARGARAAYTTYGARTTYATHTGYTAYCCN GGNGCNGGNCAYATHATHGARCCNCCNTTYYTNCCNYTNTGYMGNACNAAYTAYAAYCCN ATHTTYAARATGTTYTTYYTNTGGGGNGGNCARCCNAARCARCAYGCNCAYGCNCARATH GAYAGYTGGCCNMGNATHGTNGCNTTYTTYAARAARCAYYTNATGCAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TTYGTNGCNCAR GGNAAYGTNATHGTNGTNACNATHAAYTAYMGNYTNTCNTGGYTNGGNTTYGTNMGNGGN CCNACNGARGARGTNAARGGNAAYATGGGNYTNTGGGAYCARYTNGARGCNATGMGNTGG GTNAARAARAAYATHAARGCNTTYGGNGGNGAYCCNAGYGAYGTNACNYTNGCNGGNCAR TCNATGGGNGGNGARAGYGTNTCNGCNATGAGYGTNATHTCNCARGCNAARGAYYTNTTY ACNAARGGNATHYTNTTYAGYGGNACNATGTTYACNTGYMGNTCNAGYYTNGGNTCNTCN GAYGTNYTNYTNGAYATGYTNGTNAAYAARYTNGGN------YTNACNMGNTCNGAYTCN GARYTNATHGARGARYTNAARAAYYTNCCNGARGARAARTTYGTNYTNCCNYTNCARAAY GARATHACNAAYAARTTYACNACNATHGAYGGNGAYATGTTYCCNAARTCNTTYGAYGAR ATGAARCARGAYAARGAYTAYYTNTCNAARGTNGGNTTYTTYAAYMGNGAYTAYYTNGTN TCNATGACNAAYAAYGARGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATGCAYCCNTAYTAYTAYGTNCARTAYGTNCCNATHCCNYTNAARCARGAYYTNGAR ATGAARGTNAAYTGGGCNGCNTCNCCNAGYACNGCNCCNAARCARGAYACNAGYAARCAY TTYCAYGTNTTYGTNGGNGAYYTNAGYGCNGAYATHGARCARCAYCARYTNMGNGAYGCN TTYTCNATHTAYGGNGARATHTCNGAYTGYAARATHATHMGNGAYCCNGCNACNATGAAR TCNAARGGNTAYGGNTTYGTNTCNTTYGTNAAYAARCARGARGCNGARACNGCNATHTCN GGNATGAAYAAYCARTGGYTNGGNACNMGNCCNATHMGNACNAAYTGGGCNACNMGNAAR CCNYTNGCNCCNCCNACNAARGARAAYGCNAARCCNYTNGCNTAYGARGARGTNTTYAAY CARTCNAGYTCNACNAAYTGYACNGTNTAYTGYGGNGGNGTNACNAAYGGNYTNACNGAR GARYTNATGMGNAARACNTTYTCNCARTAYGGNACNATHCARGARGTNMGNGTNTTYAAR GAYAARGGNTAYGCNTTYATHMGNTTYAGYACNAARGARGCNGCNACNCARGCNATHTGY GCNGTNCAYGGNACNACNGTNAAYGARCARCCNGTNAARTGYTCNTGGGGNAARGARTCN AAYGARTCNAGYCARAAYACNCARCARTCNAAYAGYCCNCCNGTNGTNATGGTNCCNTCN CARCARCARCARCCNATHGCNGCNACNCCNGCNGCNAGYCCNTAYGGN---CARTTYTAY AAYATGAAYTAYTAYCAYGGNGCNCCNTAYGCNGCNGGNAGYCCNGCNTAYCARAGYGCN GTNCCNACNCARGGNCARTTYATHCCNGCNGCN---GGNCARTGGCCN---AGYTAYTCN AAYTAYCARGCNTAYGGNAGYATGAAYGTNCCNGTNGGNCARTAYGCNGGNYTNCARATG GCNGGN---GCNCARCARCARCARTTYGCNAGYCARGGNCARGGNGTNGTNGGNTAYCCN ATGCARCARGGNATGGCNMGNCCNAAYGTNMGNTAYGARGTNYTNCCNTCNGARGARCAR AAYGTNGCNGCNGARCCNGTNGAYYTNGCNATGGCNGTNCCNCCNCCNAGYTAYACNGAR ACNCCNGTNATGGCNGARGGNGGNGARGARCCNGTNTGYGGNCCNGCNAARYTNCCNAAY TAYGARGARGCNACNACNYTNCCNACNTAYGARGARGCNGARMGNTCNAARYTNGARGAR GARMGNAAYACNGGNCCNMGNACNGCNGAYTGYGARTCNGGNMGNATGACNTCNATHGAY GGNGTNAAYGARACNACNATHGGNACNGAYGGNATGTTYATHTGYACNTTYTTYATHTCN TTYYTNTTYAAYTGGYTNGGNTTYYTNYTNTCNYTNTGYYTNTCNAAYACNATHGCNGGN MGNTGYGGNGCNYTNTCNGGNYTNGGNYTNTCNATHGTNAARTGGGTNGTNATHGCNAAR ---------------------------------------------GAYTTYAAYAARYTN GARAGYCCNCCNGCNGTNGAYGGNGAYACNAGYTTYTCNCAYAGYAGYGGNAARATHAAR GTNGAYATHCCNAAYGCNGGNGCNTCNYTNGAYATHCAYACNGARCARGTNGTNAARGCN GGNACNCAYCCNTCNCARTCNGTNYTNTTYYTNCAYGGNATGMGNTTYTCNTCNAARAAY TGGATHGAYATHGARTCNATHTTYCAYGTNGCNAAYTGGGGNTGGAARGCNGTNGCNGTN GAYYTNCCNGGNTTYGGNCARAGYAARGARAAYGTNAAYGCNAARCCNGAYGGNGARTTY YTNAARAAYYTNATHCCNAARYTNGGNYTNACNAARCCNGTNATHATHTCNCCNTCNATG AGYGGNTCNTTYTCNYTNCCNTTYYTNTTYGARGAYGGNGTNGARAGYYTNGARMGNGCN TCNGGNTAYGTNCCNGTNGCNCCNGTNAGYACNGGNCAYTTYGTNAARAAYTAYAARAAY AGYCARYTNCCNACNYTNATHGTNTAYGGNACNAARGAYATHTCNYTNGGNAARATHAGY TGYAAYGAYYTNGGNCAYYTNCCNCARGGNCARTTYGCNCCNATHGARGGNGCNGGNCAY GCNTGYTAYYTNGAYAAYCCNGAYGCNTTYCAYAARTAYYTNTAYTTYTTYYTNAAYAGY YTNGTNATHGCNGGNATHYTNACNATHGTNYTNYTNAARTAYTGYTAYGAYTTYTAYYTN TTYTGGMGNTTYTTYCARAARYTNCCNGGNGARACNTCNTTYCAYYTNYTNYTNGGNAAY ATGCAYAARYTNCCNGGNCCNAAYGARGARGGNYTNCARTAYGARATGGARCARATGGAR AARTTYAARTAYYTNMGNMGNGTNTGGGCNGGNCCNTTYGTNCCNGTNATHYTNTGYTAY CAYCCNTCNGTNGTNAARACNATHYTNAARTCNTCNGCNCCNAARCCNCAYGGNACNATH ATHAGYACNCCNTAYGAYATGGGNYTNMGNTGGATHGGNGAYGGNYTNYTNYTNTCNAAY GGNGCNAARTGGAGYMGNAAYMGNMGNYTNYTNACNCCNGCNTTYCAYTTYGAYATHYTN AARGAYTAYATHAAYGTNTAYAAYAARTGYACNMGNYTNTAYATHGAYAARYTNGAYTCN YTNCARGGNGARTCNTTYGAYGTNTTYGAYCCNGTNACNYTNTGYACNYTNGAYGTNATH YTNMGNACNGCNTTYTCNTAYGARTCNAAYTGYCARACNATHAARGARCARAAYACNTAY GTNAARAGYYTNACNGARYTNGTNTAYYTNTGGACNATHMGNAGYTAYAAYCCNTTYCAY TTYATHGARTTYATHTAYGGNYTNACNTCNAARGGNMGNCARTTYTAYAARYTNTGYGAY ATHGTNCAYGARATHGGNGARGARATHATHGARAARMGNMGNACNGCNYTNGAR------ GAYGARYTNCAYGAYGGNTCNAAYCCNAARGTNMGNGAYTTYYTNGAYACNYTNATHYTN GCNMGNGAYGARAAYGGNAAYGGNYTNAGYAARMGNGAYATHMGNGAYGARGTNGAYACN TTYYTNTTYGARGGNCAYGAYACNACNACNAGYGGNGTNTCNTGGGCNYTNTAYAGYYTN GCNTCNCAYCCNAARTGYCARGARAARGTNCAYCARGARGTNYTNCARGTNYTNGGNGAY MGNGARGARYTNGARTGGGARGAYATGGCNAARYTNGARTAYACNACNATGTGYATHAAR GARTCNATGMGNYTNCAYGGNGTNGTNCCNTTYATHGARMGNAARYTNAAYGARCCNYTN GARYTNCAYGAYCAYGTNATHCCNGARGGNACNYTNGTNGCNGTNCARATHTGGGAYYTN CAYCAYAAYCCNYTNGTNTGGGAYAARCCNCAYGARTAYATHCCNGARMGNTTYAGYGCN GARAAYYTNAARACNATGGAYCCNTTYCARTTYYTNCCNTTYTCNGCNGGNTCNMGNAAY TGYATHGGNCARAAYTTYGCNATGAAYGARATGMGNGTNATHGTNTCNTCNACNATHAAR AGYTTYMGNYTNGARATHGAYGARAARGARAARCCNMGNAARTTYTTYGCNGTNACNATG AARACNGARAARGGNGCNAARATHTAYGCNTCNMGNMGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHGAYYTNATHAAYMGNGAYCCNAAYAAYYTNAAYGAYCAYGTNAAR GTNTGYTTYGAYGARGTNATHGGNGARCCNGAYGGNGCNCAYTCNATHAAYTGYGTNTGG ACNAGYTCNTAYAARTGYTTYAAYTGYTGGAARAAYTGYTGYTAYAAYYTNYTNACNATH TTYTGYGCNATHCCNATHGCNATGTGYTGGGGNTGYGARTTYGCNTAYATHACNTTYACN CAYGTNTGGCAYGTNACNCCNTGYATGMGNGCNTAYATGATHCARTGYGGNTGYATGCAR AARTTYTAYGGNACNTGYYTNCARTGYTGYATGCARCCNTGYTTYGARTCNATGGGNTTY TTYYTNAAYAAYATHAARGTNACNAARGTNAGY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AGYAARTCNYTNGAYAAYYTN GARAAYYTNTCNGAYTTYTCNTTYTAYAARGAYTGGMGNCCNMGNTCNCAYTCNYTNACN MGNAARATHGCNAGYYTNAGYAGYGAYYTNGAYAAYACNMGNAAYACNTCNYTNYTNTCN AAR---GAYTGYACNGAYYTNTCNMGNTTYTCNCARTCNYTNACNAGYCCNMGNAARGAY YTNACNGGNTCNCAYCCNCARACNAGYATHCCNATHCCNGAYACNAARGARYTNTGYMGN MGNYTNGARGAYAARATHAAYAGYYTNACNMGNATGGGNGGNAAYYTNCARAARGARAAY AARGARATGGCNAGYYTNATHGARAARCARGGNGARAARYTNGAYATGGTNAARCARGTN GARMGNAAR---------------ATGTCNGCNTCNAARACNCCNAAYAARATGGCNAAY TGGAAYCARGARACNAARGCNMGNYTNAAYGARAARATHACNTCNAAYGTNAAYGAYYTN GGNTCNYTNACNMGNCARGTNATHMGNAGYTCNAARACNAAYGARTTYYTNGCNCARGCN GCNAARAAYTTYGCNTCNCARGARAGYTAYATHCAYAAYTCN------------ACNGAR ACNAARAARATGAAYATGGTNMGNTCNCARYTNGARTTYCAR------------------ ---------------------------------CARTCNTCNATHTCNMGNAGY------ ---YTNCARTAYGTNCARGAYCARYTNTCNACNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AGYTCNAGYYTNGARATHGTNGAYGGNGAYCARAAYGGN GCNAGYGGNTTYATGTAYGAYACNTCN------TCNTCNAARCCNTCNTCNMGNCCNTGG TCNMGNTCNGGNGTNGGNTGYGTNCCNCCNMGNAGYGAYAGYAGYYTNTCNMGNMGNACN ATGACNCCNACNAARCARGTNTCNYTNCARGCNGTNMGNMGNMGNCARGARAGYTCNGAR CCNTTYGTNGAYCAYATHGAYGTNAAYAGYTTYCARCCNGARMGNAARMGNMGNCARGCN TGG---------GAYTTYAAYYTNGARGAYGGNGAYATHAGYATHTCNAAYYTNTCNGTN GGNGAYCAYAGYAARAAYCARAARAAYAARCAYYTNGCNAGYGGNACNAAYCARGAYTCN TTYTCNTCNGARCARTCNGTNAAYGGNGGNCARGAYAAYAARACNATHAARAAYAAYGAY GGNAARAARGAYGAYGAYTCNAGYTCNGARGAYGAYGAYAAYGAYGAYGARGAYGAYGAR GAYAARGAYGARAAYGARAARYTNAARGCNCCNACNGARYTNYTNATGGARTTYATHGAY TGYYTNATGAARAARGAYTTYCCNAAYGCNAGYAARYTNTGYACNATGATHYTNATGTAY GARCCNGARAAYGARGARGCNYTNAARTTYAARCCNYTNATHGARGARAARATGGCNYTN GAYGCNGCNGCNGCNGCNGARGARGCNGAYGAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYAGYTAYGTNATGAGYGGN TCNGAYTGYGGNMGNATHTTYATHTGGGARMGNYTNACNGGNMGNYTNGCNATGTAYYTN GARGGNGAYAARCAYGTNGTNAAYTGYGTNCARCCNAAYCCNCAYYTNCCNGTNATHGCN TCNAGYGGNATHGAYTAYGAYATHAARATHTGGTCNCCNYTNGARCARGARGCNCARTTY GAYCCNGAYGTNGCNCAYACNATHATGCARMGNAAYGARMGNATGYTNYTNGARACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGNCARATGTGYTAYACNTGYCARTTYGTNCARAAYGGNCCNGGNAAR GARTGYYTNACNGCNCCNMGNAAYTGGACNGGNGGNGAYCCNMGNATGMGNTGYCCNGAY MGNTGYACNATHATGGCNGARTAYGAYGCNAAYACNGGNYTNCCNACNTTYTTY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TTYGAYGGNGTNTGYCAYGCNGGNTAYATGGTNAAYCAYATGGAYTTYGCNCCNMGN TAYGCNGGNTTYYTNTAYGGNTAYACNAGYACNATGGCNGGNATHACNAAYGTNGTNGCN CCNYTNGTNATGGGNATHATGACNCCNAAYAARACNCARCARGARTGGMGNAAYGTNTTY TTYGTNTGYTCNGCNATHACNTTYTTYGGNTGYYTNGTNTTYGGNYTNTTYGCNMGNGGN GARGTNGARYTNTGGGCNATGTTYAARMGNGARAAYYTNMGNAARAAYTTYYTNMGNGTN AARCARAAYATHGAYCARAAYYTNGGNMGNTCNGARAARTCNGARGTNYTNTCNGARGGN CARCARGARAAYGARAARMGNGTNGARGTNGTNAARCAYGCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARAARGARAARGAYMGNCCNCCNTCNAARATHGTNATHMGNMGNYTN CCNCCNTCNYTNACNCCNGARGAYTTYYTNGARCARGTNTCNCCNYTNCCNGAYCAYGAY TTYTTYTAYTTYGTNMGNGCNGAYATGAGYYTNGGNACNAAYGCNTAYACNMGNGCNTAY ATHAAYTTYYTNCAYGCNGARGAYATHTTYATHTTYMGNGAYAARTTYGAYGGNTAYGTN TTYYTNGAYGCNAARGGNGGNGARTTYCCNGCNYTNGTNGARTTYTCNCCNTTYCARAAR GTNCCNAARAARAARCCNMGNAARGTNGAYTCNMGNTGYGGNATGYTNGARCARGAYGGN GAYTAYAARAARTTYYTNGAYCAYYTNGCNAAYCCNCCNGARCCNCCNACNGTNTCNYTN GAYGCNATHGTNGARGARGTNGARGCNAARGARYTNMGNATHGCNAARATGGGNTCNACN AARACNAAYACNCCNYTNYTNGARTTYYTNAARMGNMGNAARGARGARAARMGNATGAAY YTNGTNAARATGMGNGAYGARMGNMGNMGNGGNGGNGGNMGNGAYMGNGAYTAYGAYMGN MGNMGNTCNGGNAARGAYGARGGNGAYMGN------------------------------ ------MGNGAYMGNGAYMGNYTNAARGAYMGNGARMGNMGNAARGAYMGNGGNAARGAY MGNGTNMGNGARAARGARAARGARMGNMGNMGNGARMGNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TTYCARYTNCCNAARGARATHACNGGNATHACNAARYTNGAYGGN GCNAAYGGNCARAGYTCNTGGAARGTNAARGTNTCNTAYTGGATHAARACNTGGGTNATG GGNTCNGAYGCNATHCARGAYACNCARCCNGTNGTNGTNTAYCARTGYCARAGYCARGAR YTNYTNGARAGYAAYGCNGGNACNGCNAARACNGCNACNTTYGARAAYAARMGNTTYGGN TTYAARATHTCNGTNCAYGTNACNACNAARYTNGTNGARAAYTAYAARAGYAGYGGNCAR AAYTCNCARYTNMGNATHATHATHACNAAYGAYGCNAARATHGCNGTNACNGGNTTYGAY ATHAARYTNAARMGNCAYYTNAARTAYACNTTYAARAGYATHTGYGCNGARAAYYTNTCN GCNGCNATGGCNATHGTNGGNGARACNGTNGARATHYTNCCNGARAAYGGNATHCAYYTN ATHAARACNYTNTCNGGNTCNTCNAGYTCNGTNATG------TCNGGNAGYGGNGGNYTN GAYAAYYTNCARGTNCCNYTNACNGARAARYTNTCNGAYGGNACNATH---GAYYTNCCN CCNTCNGCNGAYGGNAARTGYTTYAARATHMGNTAYGGNYTNGAYGTNTCNGTNAGYTTY AGYAAYAARCAYACNGARACNYTNAGYYTNGTNATHCCNGGNGTNYTNCCNGGNTAYAAY ACNCARTGGGCNTCNTGGAARGCNCCNGAYTGGGCNTTYGGNTGYGARACNAARYTNTCN AAYTCNYTNTTYTCNGTNGCNGARMGNATHYTNTAYACNGARGCNTTYTCNAGYYTNCCN AGYTTYCARGTNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CCNGARAARATHMGNGGNGGNGGNGARYTNTTYAARTTYCCNTGGACNTCNTAY TCNAARGCNCARCARTTYCCNGTNAARTTYTAYTGGAARCAYAGYMGNGTNTTYMGNTTY TTYTTYTAYTCNTCNYTNYTNTTYTTYCCNYTNATGGTNAARYTNACNAARGTNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGGCNGAYACNATHCARATHYTNAARTGY GGNGTNMGNTTYTCNCCNCCNACNYTNGTNYTNACNTAYAARGAYTGGAARAGYGGNAAR ATGMGNMGNMGNTCNATGCCNYTNMGNAAYTTYAGYAARCAYACNGGNGTNGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------- >occidentalis YTNYTNATHGCNCCNYTNYTNYTNGGNGTNGCNYTNGCNAGYTAYGAYCCNTAYACNGAY ATHGCNCARYTNTAYMGNATGCARYTNYTNGCNGAYGCNTTYGGNGAYTAYYTNCCNGAR AAYYTNCCNGTNGAYAAYAGYGAYGTNGAR------ATHMGNTCNTAYTGGCCNGARYTN ---------------GARGARGAYGCNGGNCCNGTNAARTCNTCNGAYGAYATGTAYGCN TCNCCNATGTAYAGYGGNGCNCAYATHMGNGAYCARGARCAYATHGARCAYAGYGCNYTN CAYGGNTAYCARTCNGTNGCNGGNGGNACNGCNGARGGNCCNGCNAAYAAYAARATHCAR AARAGYGAYAARCCNYTNCCNGCNTAYTGYAAYCCNCCNAAYCCNTGYCCNATHGGNAAR ACNGCNAARGAYAAYTGYGTNGARAAYTTYGARAAYTCNGCNGARAAYAAYAARAARYTN YTNAGYGARCARGAYTGYCCNTGYGAYACNGARCAYATGTTYAGYTGYCCNGCNGGNMGN GARACNGTNTCNTCNAARGGNAAYGCNGGNTAYCARCARACNYTNAAYAARGTNATHGAY CARYTNAGYAARATHGGNGCNGGNGARGAR------GARAAYAGYGGNYTNYTNACNCCN ACNMGNAARMGNATHTCNYTNGTNGCNAARAARTCNCCNCAYATHATHCAYAARMGNTCN GARMGNGTNAAYGARGARAAYCCNTAYYTNCARGGNACNCCNATGGAYATHGCNGCNAAR AARGAYTCNGTNTCNTCNCARMGNGCNGCNATGCCNYTNATHGTNTAYCCNCAYYTNTTY TTYATHAARACNACNATHATGATHACNACNTTYGTNGCNYTNGARMGNTGYYTNTGYGTN GCNATGCCNATGAARGTNAARYTNGTNTTYACNTCNGCNMGNGCNAARCARGTNATGACN TTYGCNTTYATHTTYAAYCCNTTYATHACNGCNYTNYTNGCNYTNGGNTAYAAYTTYGGN TAYAARATHGAYCCNTCNATHTTYTAYATHTCNAAYATHCCNGARMGNGTNTAYATHTTY GTNAGYGCNTGYACNATHATHYTNYTNACNAAYYTNATHTCNAARTCNAAYTGGMGNAAR AAYGCNAARTCNAGYGCNACNACNGCNAGYAAYAGYTCNAAYAARGAYATGAARGCNGCN AARATGATHGTNTCNGTNYTNATHYTNTTYATHATHTGYACNYTNCCNGGNATGYTNYTN AARTTYATHYTNGTNTAYGGNAARAAYYTNMGNGCNACNGGNCCNYTNTAYMGNATGTCN TTYGTNATHCAYACNGTNGTNTAYATHTTYAAYGGNATHAAYGCNACNTGYAAYATHYTN ATHTAYTAYAAYTCNAGYTCNAARTAYAARGARACNTTYCARAARATHTAYGGNTAYATH AGYAGYATHTGYATHYTNGCNGGNYTNATHCARGTNYTNTGYGGNGCNAGYATHGARGAY AARTAYGARCCNATGGTNGCNTTYATHTGYGAYMGNCCNGCNATGCAYMGNGGNATHAAY GGNTGGATHGCNGAYAARACNCARGAYTGYCCNGAYACNYTNGARGAYGTNYTNGCNTAY TGYAARAARGTNTAYCCNGAYCAYAAYATHAGYAAYGTNGTNGARTCNTCNAGYTTYTAY AAYATHTCNAAYTGGCCNATGGGNAAYGCNGGNMGNCARCAYACNCAYCAYGTNMGNCCN TTYMGNTGYYTNGTNGGNGGNTTYCARTCNGAYGCNYTNYTNGTNCCNCARCAYTGYGAR TTYGAYCAYMGNCAYGAYATHACNCARTGYAARGARTTYTCNCAYTGGAAYMGNGTNGCN GAYGAYGCNTGYATHGAYAARGGNATGCAYYTNGARTCNTTYGGNATGYTNYTNTAYTGY AAYACNYTNGGNCAYTTYAAYGGNGTNGARTAYGTNTGYTGYCCNCAYAARACNGAYCCN MGNGTNCAY------CCNGARCCNCARGCNGAYGAYAARCCNGAYAAYTGG---GAYAGY GAYGARGAYGARGAYGAYGARTAYGARGAYGAYAGYCARGAYGAYGAYGAYTAYGAYTAY TAYACNTCNACNTCNTCNTCNTCNTCNTCNAGYAGY------------------------ ---------------GARGARTAYCCNGAYGARAAYGTNGCNGAYYTNTAYGARGCNTAY YTNMGNGGNCARGCNTTYCCNGCNCARTAYAAYAAYGARCAYAARMGNTAYYTNGCNGCN AARGARMGNATGAARATGAAYCARAARAARAARGTNGCNAARYTNYTNCARGARTGGGAR AARGCNMGNGARCAYGTNAAYGARGTNMGNAARACNGAYCCNAARGCNGCNGAYMGNATG AAYGAYGARATHGCNCARMGNTTYAARCAYYTNTAYGCNTCNTTYAARCARGARGAYGAY TCNGARAAYATGCARYTNGCNGCNYTNCAYCARCARCAYATHCARGCNTTYYTNAAYGAR AARAARMGNGARGCNATGGAYMGNTAYATGAAYGCNYTNGARAGYGGNAAYACNGCNATG GTNAARAARTAYYTNCAYAGYTAYATHAARGCNGARGARAARGAYMGNATGCAYACNGTN AAYCAYTTYGARCAYATHAARAAYTCNAAYCCNAARGARGCNYTNMGNGTNCAYMGNCAY ATHATHAAYCAYYTNAARYTNTCNGARATGMGNATHGAYCARGCNYTNGARATGYTNACN CAYTAYCCNTCNATHGARATGGARGTNMGNCCNGARATHGARGARTTYYTNAARMGNTTY AAYGARATHGCNACNAGYATHAARAAYATHGTNYTNCCNGTNCCNGARGTNGAYAGYCAR GARGAYACNAGYGTNAGYAGYAGYGAYTCN------GAYAGYAGYTAYACNACNTCNAAY GAYATHAGYTTYGAYCAYGAYGAYGAYAAYAARTAYGAYACNAGYAGYGARGARGARGAR AGYGARGARGARTCNGARAGYMGNGARGAYTCNGARATHATH---GAY------------ ---------------------------GAYGARGTNCARGARGAYGARCAYAGYTAYGAR MGNGAYAAYAAYTTYGCNGCNAAYGCNCARTCNGAYACNATGAGYGCNAAYCAYGGNYTN MGNTCNTCNGCNACNTCNGGNACNCARATGGGNAGYACNATHGGNATHGCNYTNGGNAGY GTNAGYGTNTTYGTNATHGTNATHGTNGCNGTNATGATGGTNMGNCAYAAYAARAAYMGN CARTCNGTNTCNCAYGGNTAYGTNGARGTNGAYCCNTCNGCNAGYCCNGARGARMGNCAY YTNGCNAAYATGCARATGAAYGGNTAYGARAAYCCNACNTAYAARTAYTTYGAR------ ---AARGAYAARYTNTAYMGNCARATHACNGTNGARGTNAARGGNCAYGAYCCNGCNGTN YTNAAYAGYTAYCARAARTTYACNACNATGGCNGCNGARAARYTNGGNGTNAAYYTNGCN AAYGTNTCNGARCCNCCNMGNGTNATHACNMGNAARAGYYTNYTNAARTCNGTNTTYATH TTYAARAARCAYCARCAYCARTAYGARGCNMGNACNYTNTTYMGNGTNTTYGARTTYAAR CAYYTNACNGARTCNACNGCNYTNACNTTYYTNGARTAYATHCARMGNAAYYTNCCNGAR GGNATGGCNATGAARGTNACNAARCAYGARYTNCARCCNATHCCNGAYCAYYTNAARCCN CCNCARCCNTCNAARTCNTCNGCNTCNTCNGCNTCNGAYTAYTTYAAYGTNATGYTNGGN TCNCARYTNYTNTAYAARTTYGARMGNCCNCARTAYGGNGARATHYTNGCNGARCAYAAR GAYAARCCNATGTCNAGYATHTAYGGNCCNACNCAYYTNYTNMGNYTNTTYGTNMGNYTN GGNACNATGYTNGCNTTYACNTCNYTNGAYGARMGNACNGTNCAYATHYTNYTNAAYCAY GTNCAYGAYTTYYTNAARTAYATHTCNAARAAYGGNTCNACNYTNTTYAARACNTCNAAY TAYGARATHGCNACNCCNGAYTAYCAYMGNAARGCNATH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TCNAARCARMGNTGGATHCCNYTNGAR TCNAAYCCNACNACNYTNAAYAARTAYGTNCAYGGNYTNGGNATGGAYAARGCNTGGAAY TTYGTNGAYGTNTTYGGNYTNGAYCCNGARYTNYTNGCNATGGTNCCNCAYCCNGTNGCN GCNGTNGTNYTNYTNTTYCCNGAYACNAARTCN------------GARAAYACNATHGGN GARTAYATGAARGAYGCNCCNGARGAYYTNTAYTAYACNAARCARACNATHGGNAAYGCN TGYGGNACNGTNGCNYTNGTNCAYGCNYTNGCNAAYAAYCARGAYAARATHACNTTYGAY GARAAYAARGCNTTYTCNAGYTTYYTNAARGCNACNAARACNATGAAYCCNGARGAYAAR GCNAARCAYYTNGARCARGAYATGGARATGGGNGCNGCNCAYGARGAYTGYGCNCARGAR GGNGAYACNGCNGTNCCNGAYGCNTCNGAYAARGTNAARTGYCAYTTYATHGCNYTNGTN CAYTTYAAYGGNGCNYTNGTNGARYTNGAYGGNMGNAARGAYGGNCCNGTNACNCAYGGN GCNACNTCNGCNGAYACNYTNYTNGARGAYGCNGCNGTNGTNGTNAARAARTTYATHGAR AAYAGYCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ACNYTNACNCARGTNTGGGAYMGNTTY YTNYTNTAYTTYAGYCARGTNGGNCCNATHATHTTYTAYGARCCNGTNTTYMGNGAYTAY TTYTGGCARGCNYTNCARGARTTYTAYGAYGAYAAYGTNCARTAYATHGARYTNMGNGTN YTNYTNAAYGGNGTNTAYAAYYTNGAYGGNAARGTNTTYGAYMGNAARCAYGCNTTYCAR ATHTAYMGNGARGTNACNGCNAGYTTYAARAARACNCAYCCNGGNTTYTCNGAYGCNAAR TTYATHATGTCNGGNATHMGNGTNTTYAARCCNGAYGARATHYTNCARCARATHAARGAR ACNATGGCNATGMGNCAYAGYCAYCCNGAYTAYATGYTNGGNTAYGAYYTNGTNGGNCAR GARGAYACNGGNAARCCNYTNAARTAYTAYYTNGGNGAYYTNYTNTAYGCNAGYAAYCAR MGNCCNACNGTNAAYYTNCCNTAYTTYTTYCAYGCNGCNGARACNAAYTTYCARGGNACN GARACNGAYTAYAAYYTNATHGAYGCNATHYTNYTNAAYACNACNMGNATHGGNCAYGGN TAYGGNYTNGTNAARCAYCCNAGYYTNATGGCNACNGTNAARCARAARGGNATHGCNATH GARGTNAAYCCNATHTCNAAYCARGTNYTNGGNYTNGTNAARGAYCCNMGNAAYCAYCCN GCNGCNGTNYTNATGGCNAGYGAYATGCCNGTNGTNATHAGYTCNGAYGAYCCNGCNGCN TGGGGNGCNGAYCCNYTNTCNAGYGAYTTYTTYGTNGCNTTYATGACNATGATHGGNGAR GAYGCNGAYYTNMGNTCNYTNAARCARYTNGCNATGAAYTCNATHAARTAYAGYGCNATG ACNAAYTCNGARAARGARGCNGCNATGTCNGARTGGACNAARAARTGGAAYATHTTYATH ---------------------------------------------------GARTAYYTN AARGCNYTNCARAAYAGYTAYYTNTAYGGNMGNAAYMGNMGNGGNYTNAAYATGYTNMGN YTNGGNAARMGNGGN---------------GAYGTNGAYGARAAYACNGARAAYAGYYTN YTNGCNGARATHYTNMGNAAYCCNGAYCCNTCNMGNGAYCCNTCNTAYTAYGAR------ AAYYTNAARGCNYTNCARAGYAAYTAY---------YTNCAYGGNMGNTAYMGNMGNTCN ACNCCNGCNGAYGAYGTNTCNGTNACNCCNATHCCNYTNGTNAGYGAYGAYAARGARTAY GAYGAYAAYGGNYTNGCNAAYGCNGAYGARACNTAYCCNGTNTAYATHGARAGYGAYAAR GAYGGNGARYTNTTYGGN------------------------------------------ ---AARMGNGCNGGNATGGGNATHYTNMGNYTNGGNAARMGNCARYTNAAYATGYTNMGN YTNGGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TAY TGYAGYAAYAARTCNGGNATHTGYAAYCARGTNGAYGGNTAYTGGMGNTCNGCNTCNMGN ATHTTYGCNGARAAYGCNGCNGGNACNGTNTAYGTNATGGTNAAYGGNACNAARGGNGGN GCNTAYGAYAARAARAGYTAYTTYGCNGARGARCARYTNCCNATHYTNGGNGGNAARGTN ACNCARYTNGTNGTNAAYGTNGTNTTYGAYYTNGAYGARGARCCNAARGARAARTGYGGN GARAARTCNYTNYTNGARYTNGTNTCNGAYGCNAGYAARTAYGGNATHCCNTAYCARTGY ATHGAYGARCCNMGNGCNGTNAARAGYGTNYTNTGYGCNAARTAYCCNGAYGCNAARGAR TGYAARCAYGAYGARGTNYTNAARATGATGAARCARATHCAYGARATGTGYCCNAAYATH ACNMGNYTNTAYAAYYTNACNGARCCNTCNGTNCARAAYMGNAGYYTNACNGTNYTNGAR ATHACNGARAAYCCNGGNGTNCAYACNCCNGGNAARCCNGARTTYAARTAYGTNGGNAAY ATGCAYGGNAAYGARGTNACNGGNAARGARATGYTNYTNTAYYTNATGYTNGCNATGTGY GARGARTAYATHAAYGGNAAYGARYTNGTNMGNTTYATHGTNAARGARACNMGNGTNCAY ATHYTNCCNACNATGAAYCCNGAYGGNTGGCARGCNGCNGAYGAYTAYMGNAARGARCAY GGNAARTCNGAYTGGYTNACNGGNMGNGCNAAYGCNAAYAAYGTNGAYYTNAAYMGNAAY TTYCCNGAYYTNAAYGCNAARATGTAYAARAGYGARAARGARCAYMGNGGNMGNAAYAAY CAYYTNGTNAARGTNGARAAYGCNATHGCNAAYGAYGARTCNYTNCARCCNGARACNMGN GCNGTNATGMGNTGGYTNGCNAGYATHGGNTTYGTNYTNTCNGCNAAYYTNCAYGGNGGN GAYYTNGTNGCNAAYTAYCCNTAYGAYGARACNMGNTCNGGNAARTCNCARGARTAYACN GCNTGYCCNGAYGAYCAYACNTTYGTNTTYYTNGCNAARTCNTAYGCNYTNGCNCAYMGN ACNATGGCNGAYCCNGARMGNGTNCCNTGYGAYGCNGAYGGNGAYAAYAARCCNATHACN AAYGGNGGNYTNTGGTAYTCNGTNGCNAAYGGNATGCARGAYTAYAAYTAYYTNAAYACN AAYTGYTTYGARATHACNYTNGARYTNGGNTGYGAYAARTTYCCNCCNGCNTCNGARYTN GARCARTAYTGGGTNGAYAAYGTNGGNGCNYTNTTYAAYTAYATGYTNCARGCNCAYAGY GGNGTNAARGGNTTYGTNACNTCNAARAGYGGNGARCCNATHGARAAYGCNGARATHAAR GTNACNAAYYTNGCNTCNGGNYTNCCNGTNGARCAYGAYATHYTNTCNYTNGARGGNGGN GAYTAYTAYMGNYTNYTNGGNAAYGGNTAYTAYTTYATHMGNGCNGAYGCNTCNGGNTTY CAYCARAARGGNCAYTGYATHCAYATHCARAAYAAYYTNCARATHGGNGARACNAARGAY GARYTNCAYCCNGCNCCNGTNYTNAAYTTYGTNYTNACNCCNGAYAGYGARGARGCNGAR CCNGTNAGYCARGARGAYGARGARTGYCARMGNYTNTCNGAYGARATHCARGCNAARACN CARATHGARGAYMGNGAYYTNYTNGTNTCNATHYTNTCNTAYYTNGARCCNGGNTAYAAR TGGTCNTAYTAYGCNCAYTGGATGACNACNYTNGARYTNTAYTAYTAYYTNGTNGARGCN YTNCARAARYTNGARCCNTCNGAYATGMGNGCNGTNYTNCAYAARYTNCCNAARGCNGTN YTNGARCARYTNGARYTNGTNATHATGGCNGAYYTNATHCAYAARATHTTYGGNCCNAAR CAYAGYAARGGNAGYAGYGARGGNAARCARACNAGYGARCCNGARGGNTAYACNAARCAY CARCAYGARTTYTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CARACNTTYTCNGTNCAR TGYGTNYTNTCNATHAAYATGTTYYTNGARAARATGTAYYTNATHYTNTGGTTYTGGYTN ATGATGATGYTNGTNTTYAAYTCNATHAAYYTNATHCARTGGYTNTAYMGNGGNYTNGTN CCNAGYAARGGNGARGAYTTYATHMGNAARTAYYTNYTNYTNYTNGGNATHGAYTCNAAR MGNCARAARAARYTNTTYGTNMGNTTYGTNAARAARTAYYTNMGNACNGAYGGNGTNTTY ATGYTNMGNATHGTNGCNGTNAAYACNAGYGARATHYTNACNACNGAYYTNYTNMGNCAR YTNTGGAAYAARTTYMGNGARACNCAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------AGYYTN GTNACNTGYYTNCCNAARMGNTCNGCNGAYGAYATHYTNCARGAYACNTCNGGNATGGTN YTNGAYAARMGNCCNAARTAYATGGAYACNMGNMGNGAYYTNGAYGTNTTYAARGAYYTN GTNYTNATGAGYGTNCARGARYTNGTNGAYGARGGNMGNYTNGARTCNTCNGTNYTNCCN GARGAR------GAYMGNGARACNAGYAARCCNGTNGARAARMGNMGNTAYATGGGNYTN TGYATGCAYMGNCARGCNAAYCARTAYATHCCNTTYCCNTGYYTNMGNACNGGNMGN--- ---------TTYYTNGTNYTNGTNGGNTGYGCNGCNYTNGCNGTNGCNGAYAAYTAYYTN TGYCCNCCNCARGARGGNYTNCARTTYGTNTGYTAYGARTCNGAYCCNAGYTAYMGNGCN TGYYTNACNAAYGGNMGNMGNAGYGAYTCNTAYGTNGTNTGYTCNAARTGYAARMGNAAR TGGGARTTYTGYGTNACNMGNGGNGCNTTYCARGARTCNAARCAYCCNGARGTNGAYTGY GGNGCNGAYTAYAARGAYACNCCNTGYACNCCNGAYAAYTCN------------------ ATHYTNGTNCAR------TGYCAYATGYTNACNGCNTTYCCNAGYTTYATGAGYAARATH CCNAAYGGNAAYAARGTNCCNAAYCCNACNAARCCNGGNACNATHTGGTAYGGNGTNGGN CAYYTNGCNGCNGGNGGNGGNGGNCCNMGNAAYCARTTYGGNATGGAYTTYGCNGCNGCN GGNAARATHTGGACNGTNGARYTNTGYCARATGGAYTCNGAYGGNGAYGGNYTNTAYAAY GGNGARGARYTNGGNGAYCCNGAYTGYGTNTGGACNCCNGGNGARACNCCNGCNTCNAGY ACNGGNYTNTCNCAYCCNGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNYTNACNYTNAGYYTNTTYGCNGGNAGYACNTGYGCNGTN TTYTAYATHCCNGGNTCNGTNGTNAGYTAYCCNAARATGGGNAARMGNGCNTTYTAYACN AAYGCNACNGGNAAYMGNTAYCCNYTNATGGGNMGNMGNTCNGARCCNACNGCNCARCAR GGNCARGGNCARGGNCARGGNCARAGYCARAGYGARATGGTNGARGGNCARGCNYTNGTN GARTTYAAYAARMGNGGNGTNTTYACNAARGGNCCNCAYMGNAGYTAYCCNMGNGTNGGN MGNTCNGAYCCNGCNAGYGARAAYTTYAAYACNGTNGTNAGYGARAARGTNMGNAGYCAR ATHYTNAARCCNATHAGYGGN---GARGAYTCNCCNAARGCNYTNCARYTNCCN------ ------------------------------------------CARYTNYTNTTYYTNGTN TTYGAYGARAAYGGNGAYAGYCARYTNACNAARGCNGARTTYACNYTNGGNYTNGCNAAR GTNATGGARCARAAYYTNYTNTGY------------------------ACNGAYGARGGN CCNGTNAARYTNMGNYTNGGNYTNACNYTNYTNAAYATHGARAARGTNAAYYTNGARACN AAYGARGTNACNYTNCARGCNTGGYTNGARAAYCAYTGGAAYACNGGNGTNACNTTYAAY CCNGARMGNTAYCAYAAYGCNTCNGTNGTNMGNGTNCCNMGNTCNAARGTNTGGYTNCCN GAYYTNGCNGTNTAYAAYGGN---------------CARYTNGAYYTNCCNCARAAYGTN ATHATHACNTCNGAYGGNGARGCNACNTGGATHCCNCCNGTNAARATHMGNGTNTTYTGY GAYATHCARGAYGCNACNYTNAARGCNAAYACNACNTGYCAYATHAARATGGGNTCNTGG GTNTAYTCNGCNTTYGAYYTNGCNYTN---AAYGAYAARCCNTCNTTYGGNYTNGAYTCN TAYATGACNGARTCNYTNTTYGARGTNGTNTCNGTNTCNGCNAARMGNAAYGCNATHTTY TAYCCNTGYTGYCCNGARGARTAYCAYGAYATHGCNTTYTTYTTYACNTTYMGNAARAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGYMGNTCN GCNGARTGYTTYAARTAYTTYTGYAAYTCNTGYTGGTCNTGGCAYCAYTCNATHGAYAAY YTNMGNYTNCAYMGNCCNYTNACNMGNCAYAGYAARAAYTCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARTAYGTNACNAARMGN MGNTCNATHAAYGARATHGAYMGNCARYTNCARAAYYTNYTNGTNGAYAARAARAGYGCN CAYGCNTTYYTNTCNAARMGNCARAGYAGYCARGAYATHATHTGYGARTGYTGYGTNAAY CARTGYAGYTTYATGGARYTNYTNCARTAYTGYGARYTNCCNAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYGTNMGNYTNCCNMGNTCNATHGTNCCNAGY CAYTAYAAYGTNMGNYTNCARGGNGAYTCNCARAAYTTYACNTTYAARGGNTAYGTNTCN ATHMGNGTNAARTGYGTNGARTCNACNGAYAAYATHACNYTNCAYGCNAARACNYTNAAR ATHAAYACNGAYACNYTNYTNGTNGCNTCNMGNGAYCCN---------ACNATHYTNGGN ACNGARGARGAYGAYGAYMGNCARTTYTTYATHGTNAARYTNGGNACNAAYYTNCARAAR GAYMGNGARTAYGTNYTNTCNATGAAYACNTCNCCN------ATGGGNACNGGNACNGGN YTNTAYYTNACNTCNTAYCAY---AAYAAYCARACNGTNTAYATGGTNGCNTCNCARTTY GARCCNACNGCNGCNMGNACNGCNTTYCCNTGYTTYGAYGARCCNGCNYTNAARGCNACN TTYAAYATHACNYTNGCNMGNAARGCNGAYYTNYTNTCNATHTCNAAYACNCCNATHATH GAYAGYAGY---------GARAARTGGACNGARGAYGGNTAYCARCARACNCCNMGNATG TCNACNTAYYTNYTNGCNTTYATHGTNTGYGCNTAYGGNTAYACNTCNAARACNACNGAR AAYGGNGTNCARTTYMGNGCNTTYGCNMGNCCNGARGTNACNGAYTCNACNTGGTAYGCN YTNAAYACNGGNGTNAGYGTNYTNCCNTAYTAYGARCARTAYTAYGARACNAARTAYCCN YTNCCNAARCARGAYATGATHGCNATHGGNCCN---GGNCARGGNGGNATGGARAAYTGG GGNYTNATHACNTAYGGNGARGCNTCNATGYTNTAYACNGAYGGNGTNACNACNGCNGAR AAYAARGARCAYGTNTCNATHGTNGTNTCNCAYGARYTNGCNCAYATGTGGTTYGGNGAY YTNGTNTCNCCNTAYTGGTGGGAYGAYYTNTGGYTNAAYGARGGNTTYGCNAAYTTYGTN GARAAYATGGGNGTNGAYTTYGTNCAYCCNGAYTGGAARATGTGGGAYAARTTYGTNGTN AAYTCNGTNCAYGAYGCNYTNMGNACNGAYGGNAARGCNACNTCNCAYCCNGTNTAYGTN CCNGTNAGYAAYCCNGAYGARATHCARAGYATHTTYGAYATHATHACNTAYAAYAARGGN GGNTCNATHGTNMGNATGATGMGNCAYTTYYTNGGNGARGARACNTTYMGNMGNGGNYTN GTNAARTAYYTNCARMGNCAYAARTAYGAYGTNGCNACNCAYAAYGAYYTNTGGAARGCN YTNGARGAYCARGCNGGNAARGAYYTNAARGTNAARGARGTNATGGAYACNTGGACNYTN CARATGAAYTAYCCNGTNGTNACNGTNACNAAYGAYATGAAYATGGTNCAYATGACNCAR TCNMGNTTYYTNGTNAGYMGNAAYGTNCCNGAYCCNGGNAARTAYACNTCNCCNTAYGGN TAYAARTGGACNATHCCNATHACNATHACNAGYAGYMGNAAYAARAARGARGARGCNTCN ACNMGNTTYAAYGTNGGNGARGCNAAYYTNCCNAAYGAYAARAAYGGN---TGGATHYTN TGYAAYACNGARCARCAYGGNTTYTAYMGNGTNAAYTAYCARYTNGGNAAYTGGAARGCN YTNACNAARCARYTNAARACNAAYCAYAGYGTNATHTCNGCNATHAAYMGNGCNCARATH ATHAGYGAYACNTGGAAYYTNATHAARTCNGGNGARYTNAAYGTNGARACNGCNYTNGAY GCNGTNAAYTAYYTNGARMGNGARAARGAYTAYGTNCCNTGGAARGCNGCNAAYACNGAR YTNGGNTAYGTNACNGGNATGYTNTCNYTNACNCCNGCNTTYGGNYTNTAYGARAARTTY ATGYTNGARTCNACNGGNCCNTTYAAYATGTAYTGGYTNGAYAAYACNMGNTCNACNCAY ATHGARACNCARACNMGNTCNCARGTNGCNATGGTNGCNTGYGARTTYGGNAAYGCNTAY TGYYTNMGNGARTCNTCNMGNCARTTYAARAGYTGGATGGGNAAYAARAAYAAYAAYATG ATHGAYYTNAAYYTNATHATHTAYTGYACNGCNGTNMGNCARGGNGGNTGGGAYGARTGG AAYTTYGCNYTNGAYATGYTNAARCARACNACNATHACNGCNGARMGNGCNAAYYTNYTN MGNGCNYTNTCNTGYTCNACNAARCARTGGATHYTNAAYAGYYTNYTNTAYGTNYTNGAR GARAGYTCNCCNTTYCAYGGNTTYGARGCNGTNACNGTNATHMGNAGYGTNGGNACNTCN CCNCAYGGNMGNGTNYTNGCNTGGCARTTYTAYMGNGARAAYTTYGAYAARATH------ ---------AAYGAYGAYTTYAGYGGNATHAGYYTNGTNACNGAYYTNACNAGYACNTTY AAYACNGARGGNCARATGAAYGARGTNAGYAAYATGAARGARATGAGYAARAAYAARGGN GCNCARCCNTCNYTNGAYMGNGCNYTNGARACNATHMGNGCNAAYTCNGAYTGGATGGCN AARCAYTAYAARCCNYTNCARGCNTGGYTNATGACNTCNMGNGGNTCNTCNAGYATHTCN CCNCCNGTNCARATH---------MGNCAYGTNTCNACNATHCCNTCNGGNACNCCNCCN CCNAAYCARCAYYTNTAYCCNGGNCARTCNCCNGGNYTNGTNCARGGNACNTTYAGYTAY ATHCAR---CCNCARTAYCARCARGGNGARCARTTYYTNCCNTAYCARGCNTAYGGNAGY GCNCCNAAYGAYYTNMGNGGNGCNTCNTCNTCNAGYGGNMGNGGNGGNGCNGGNCCNGCN CAYATGGCNCARTCNGGNACNTAYTAYCAYCARACNAGYCARAAYATGMGNCCNTCNCAR CCNCCNCCNCCNAAYCAYTCNCARCCNTAYTAYATHAGYCARACNGGNCARGGNAAYATG MGNCAYCCNMGNCCNAGYTCNGCNTCNAAYCCNCCNATHATGTTYTTYCARCCNACNCCN AAYAAYATGGTNATHTCNAAYATGTAYCARCARACNACNMGNATGCCNATG--------- ---GGNGGNCCNCARTAYCARMGNTTYAAYCARCCNAGYGGNATGATGTAYTTYAAYGGN CARMGNCCNTCNATGCCNATGCARGCNCARGGNGGNCCNCCNGCNCCNMGNGARAARMGN ATHATHAAYATHTGYGAYCCNAAYACNGGNMGNAAYATHACNGAYGARATHTCNCAYAAR CCNTCNACNGAYGARAARGCNGARCAR---GARGAYTCNTCNGCNAAYGAYAARGGNGTN GARATHMGNAARAAYTTYACNMGNCARGTNGTNGARMGNATGAAR---------ATHGGN GARTCNCCN---GCNGCNCARCARTCNTCNGARCCNGTNACNCARTCNGGNAAYCCNTCN CARCARAAYCARGCNAGYCAR------------------------CCNGCNTCNTAYCCN CCNGGNCAYCCNCARCCNCCNCARTCNGCNTCNTCNYTNACNGGNGCNGTNCCNGGNTCN ATGCCNCAYTCNATHMGNATGGGNAAYCARGAYATHAAYYTNAGYATHCCNCCNCCNCAR YTNCCNCCNAAYATG---------------------MGNCAYGGNYTNAAYCARCARGCN ATGCCNGGNCARGCNTCNGTNCARACNCARGTNATHCCNCARAARGGNTAYCCNGCNCCN GGNGARGTNGAYGCNGCNAARCCNTCNCCNGCNGARGCNCARACNGGNACNGTNCAYGTN TCNAGYGGNGTNGARGARACNATHGCNTCNCCNGCNYTNTCNAARCARTCNYTNCCNGCN TCNGAYCCNACNCARYTNTCNGCNTCNGTNGCNTCNGARAARCCNGAYACNGGNCCNTCN AGYGARTCNGCNGCNCCNGCNAARCARCCNYTNCCNACNAARAARCCNGARGTNAARGAR GARACNGGNGGNGGNGCNAGYGCNCARGGNAAYAARGAYGGNMGNAARGGNAARAARAAY AARAARGAYTTYGGNMGNAARGARATHGGNGGNTCNGARATGGAYGCNTTYACNGAYGGN AARGAYAGYGGNGTNGAYTCNGARCCNGGNYTN---GCNGTNCARGARCARAGYCARYTN TCNGAYAGYAARGTNCCNTCNCCNCCNATGCCNGTNGAYGAYAARTCNCARGAYGTNGAR GARGARGARGCNYTNCCNACNGCNATGCCNTCNACNCCNGTNGARAARACNAAYGCNGTN ACNGARGAYAGYCCNATHACNGARGARGCNGCNTCN------AARATHGARTCNGCNAAY GTNCARTCNMGNAARGARGCNAGY---GTNCCNAARGAYAAYCCNCCNGTNGTNAAYTCN GTNCCNGARGTNATHCCNGCN--------------------------------------- ---------------------------------AGYGAYGAYGTNGAYTCNGARGTNAAY GAYCARCAY------ACNGARGARAAYAAYATGCCNAARGTNGARGAYGTNGARCCNTCN AARGCN---------------GARGTNTAYGCNAARYTNAARAAR---AGYGGNGGNAAR YTNGTNTAYGAYMGNGCNTAYYTNATGGARYTNMGNGAYTGYGCNTCNTCNCARGCNAAR CCNGAYGGNYTNCCNGCNYTNGARATHATHYTNGAYCARCCNAGYCCNTAYYTNTCNMGN TCNTCNYTN---GGNCCNGCNGAYTTYACNCCNGCNTTYTTYCARACNGGN---GCNAAY CARMGNCAYGCNCCNCCNATHGGNAARAGYAGYAGYMGNGGNMGNCCNMGNCCNGGNGAY ATGCCNGGNACNCCNMGNATHATHAARAGYATHTCNATGTCNAAYGAYACNAARCARYTN CAYCARAGYGAYAAYCCNTGGAAR---------CCNACNAARAARGARGAYAARAAYGAR CARAARACNYTNGARGGNGARATHYTNTTYATHATGAAYMGNYTNACNCCNACNAAYTTY GARAARYTNGCNAAYGAYATGAARGCNYTNAAYATHAARTCNTAYGARGAYYTNCARTTY ATGGTNAARACNTTYTTYGAYAARGTNACNYTNGARACNAARTTYGTNGARGCNTAYGCN CARYTNTGYAARGTNATGTCNGGNYTNMGNGTNCCNCCNCCNACNGAYGGNTCNGTNAAR GARAAYATGGCNACNTTYMGNGTNGTNATGYTNACNAARTGYCARCARGARTTYGARGCN GAYAARTCNATHATHTTYGARGAYCCNGARGARAARMGNAARAARYTNGARGCNGARAAY CCNGARAARACNCCNGARMGNATHGARYTNATHGARCARACNYTNTAYAARATGAARYTN AARMGNATGAARTTYTAYGGNAAYATHMGNTTYATHGGNGARYTNTTYAARYTNGGNATG YTNACNGARAAYATHATGCAYGAYTGYATHTAYMGNYTNYTNAARGCNMGNGAYGAYGAY TCNYTNGTNTCNYTNTGYAAYYTNYTNACNACNGTNGGNMGNAAYYTNGAYACNGAYAAR GCNMGNCCNMGNATGGARCARTAYTTYTCNCARATGACNAARATHGCNGAYGARMGNAAR TCNMGNATHAARTTYACNYTNMGNGAYGTNATHGARYTNMGNCARAAYAAYTGGATHCCN MGNAARCARGCNACNGGNCCNAARAARATHGAYGARGTNCAYAARGAYTTYGCNCARGAR CARATGMGNAAYCARTAYYTNGCNTCNCARCCNCCNCCNCCNMGNAAYGAYAAYTCNCAR GCNGGNAGYMGNMGNGGNAGYMGNCARMGNCCNGAYGARAAYAARATGGGNGARGAYGGN TGGAAYACNGTNGGNAAYCCNAARTCNTTYMGN---ATHGAYGCNTCNAARATGAARATH TCNTCNAARAAYGTNGTNGAYGAYAAYATHCARYTNGGNCCNGGNGGNGGNGCNCAYAAR CARCCNATHTGGAGYMGNGGNAGYCAYGGNGGNACNCARCARCARCCNCARGAYGAYMGN CCNGCN---YTNGGNAAYMGNTTYTCNGCNYTNACNAGYGAYGAYGCNMGNMGNTCNTTY CCNMGNTCNCCNTCNMGNGGNGARGGNTCNGCNGGNMGNAGYYTNMGNCARGGNCARTCN GCNGGNCAYGGNMGNGGNAARATHATHTCNMGNTCNAGYCARGAYGGNGARMGNMGNGAY GCNATHGCNAAYGCNMGNACNTTYATGGGNGGNMGNTCNCARAAYTCNAGYMGNGAYAAY AGYTGGAAYMGNGAYGAYMGNMGNCARTTYATGGGNACNMGNAGYTCNTGGGARMGNGAY AAYCCNATGACNMGNAGYGAYAGYGCNGTNMGN---ACNGARGARTTYAARACNCCNGCN CCNCCNCCN------GTNAARCARATGTCNGARTCNGARYTNGARACNAARGCNGTNAAY ATHYTNGAYGARTAYYTNAAYATHMGNGAYYTNTCNGARGCNAARYTNTGYATGAARGAR YTNGGNGGNCARAGYCARATHCAYGCNGTNGTNACNGCNAGYATHAAYAGYGTNYTNGAR AARMGNGAYGAYGCNMGNCAYATGACNGGNAAYYTNTTYCAYGARYTNGTNAARAGYGAR ATHATHAGYTCNAAYGCNTAYGTNAARGGNYTNAAYAAYGTNYTNGARTAYGCNAGYGAY ATGGTNGTNGAYATHCCNACNYTNTGGAAYTGYYTNGCNCARGTNATGTCNCCNYTNYTN GTNGGNGGNACNYTNCCNTGGTCNAARYTNMGNCARGCNTTYACNCCNCAYYTNAAYAAY AARGAYGGNGCNAARYTNYTNGCNGCNYTNYTNTCNCAYTGYGTNGARAARCARGGNGAR AARGARGTNTCNMGNGARTGGCARGAYAGYGGNYTNTCNTGGTCNGCNTAYYTNAARCCN GAYGARYTNAAYGCNTTYGTNTCNGAYAARAGYYTNGAYTTY------------------ ------------------------ACNYTNGGNGCNCCNGGNGGNGTNGGNYTNYTNCCN GAYYTNGARAARATGATHTGYAGYMGNGCNTCNAAYAAYGARYTNGTNTCNTAYATHGAR AARTCNGTNCCNGGNAGYAARACNGAYCCNAGYTTYATHMGNGCNYTNACNACNGCNGTN GTNGGNGCNTCNATHAAY---------GARAAYAARAAYATHAAYGTNGARGTNATHAAR AAYAAYAARGAYYTNYTNCARMGNTAYYTN---GGNAAYAARGTNGARYTNCARYTNCAR GCNYTNTAYGCNATHCARACNYTNATGGTNAARYTNGARCAYCCNTCNGGNGCNYTNAGY AARYTNTTYGARYTNYTNTAYGAYGARYTNTCNATGGARGARGARGCNTTYTAYMGNTGG GARAARTGYAAYGARCCNCARGARCARGARGGNAARGGNACNTGYYTNATGCARGTNMGN CAYTTYTTYATHTGGYTNMGNGARAAYGARGARCCNGAYGCNGARTCN------------ ------------------------------------------------------------ ---------------------------------------AGYTGGTTYGAYGAYYTNGAY CCNGAYYTNTCN---GGNGAYCCNYTNGGNGAYGAYAGYATGGARGCNTTYGTNAAYYTN GAYAARTTYYTNAAYGGNAAYTCNTTYTTYGAYGAR------GAYGGNAAYATGACN--- GTNCCNGARGARGCNGARGTNACNCCNGTNATHGAYTTYAARGARCARGTNGTNGCNAAY CCNGCNGAYTTYATHACNCAYTAYGAYAAYAAYCARGAYTTYYTNYTNTCNCCNGTNGTN AARAAYTCNMGNAARMGNACNGCN---GGNTCNMGNGGNGGNGTNAARACNAGYYTNTAY GARATHCCNACNACNACNGTNATHCCNGARGTNMGNGARGAYTCNAAR------CCNYTN TCN------GAYACNGARYTNGAYCAYGAYTAY--------------------------- ------------------------------------------------AGYACNAARMGN CARMGNYTNAGYGAYCCNYTNGGNAAYGARAGYACNCCNTCNACNAGYGGNACNGTNATH GAYCCNGTNYTNYTNYTNGAYAARAGYATGGAYAARCARACNGTNMGNMGNATHAARAAY AAYCAYGCNTCNAARMGNTCNMGNGARCARMGNAARCARAARTTYGTNGAYATGGAYYTN GARGCNGARCARYTNGTNGTNMGNAAYCARGARYTNMGNGCNAARATHGTNGARYTNGAR MGNYTNGCNAARGARATGAARGCNGTNYTNGTNGCNAARATGGCNGGNMGNGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYGGNACNGCNGGNGGNAGY GARGTNTCNTCNTCNTCNGCNTCNTCNTCNYTNCCNCCNCCNACNYTNTCNGCNCARTCN GAYGCNGARGGNGCNGTNGGNGGNGARAAYACNCCNTAYAAYCARGAYATHGTNCCNGAY ATHAAYAARAAYAAYMGNYTNAARGAYACNTCNGGNGTNTCNAGYAGYTCNCARTCNTTY GTNTTYGGNAGYAAYYTNTCNCARMGNGTNACNGGNATHYTNTCNTCNCCNATHGTNGGN AAYGARGCNTCNGCNTCNGCNGGNTTYGTNTTYGGNGARTCNYTNGTNTCNMGNGCNGTN GTNGARACNAAYGGNTCNACNCARCCNGAYAARGAYGAYGARAGYGAYTCNGAYTCNGGN AAYAARYTNAAYCARACNYTNGARGARTCNGCNMGNGARTAYCARGCNAARCAYGARATG AARACNGARYTNAARGARGTNGARACNATHACNGGNGARGARGARGARTCNAAYGTNYTN CARGCNAAYGGNAARYTNTTYTTYTTYGARACNAGYAAYGARTCNTGGGTNGARMGNGGN MGNGGNACNATHMGNYTNAAYGAYATGTCNGCNMGNGAYGAYACNAAYTTYCARTCNMGN YTNGTNATGMGNACNCARGGNAGYYTNMGNGTNGTNYTNAAYGCNAARATHTGGCCNGGN ATGTCNYTNGARMGNGCNTCNTCNMGNTCNATHMGNATHACNGCNATGGAYACNGAYGAR TCNATHAARATHTTYYTNATHACNACNAAYGTNAARGAYTCNGARAAYYTNYTNMGNGCN ATHGAYTGGMGNATHCARCARYTNAARATHCARGAYGARCCNGTNMGNCARCAYTCNGTN TCNMGNACNGGNGAYAARMGNAARGCNGARGARTCNGAYTTYGARYTNCCNGTNAARAGY AARAARGTNAAYAGYTCNCCNGAYCARGGNATHTCNATGACNAARAARGARGARTCNGAY AGYAGYGTNCARGAYCCNGARACNGARGCNTCNTGYGARAGYCAYTCNTCNTCNYTNACN ATHAARTCNGARTCNGAY------------------------------------------ ------------------------AARGTNACNAAYTGYAARGCNTGYGGNAAYATHGTN GAYAARTAYGTNGARTAYGAYTCNGCNATHATHYTNYTNGAYGTNYTNYTNYTNCARMGN CARGCNTAYGCNCAYYTNYTNATHAAYGTNGARGTNAARTCNCAYTGGMGNTTYGCNGTN YTNYTNTGGGTNGTNGARGCNTTYATHAARYTNATHCARCARMGNTCNGAYYTNGCN--- ------AAYACNAARGCNAGYGAYTCNACNTAYTCNTTYGTNGGNGTNGARYTNTAYYTN AAYTAYATHGGNGCNGCNGTNGARYTNATGAGYTTYYTNYTNTGYGTNYTNGCNTTYYTN GCNGTNMGNAGYATHGTNYTNACNAARAGYYTNAARYTNYTNAAYACNTTYATHATHATH AARGCNATHYTNYTNTCNAAYYTNGGNTCNYTNYTNGCNATGCCNGCNYTNYTNTGGGGN AARTCNTGYATHCCNTGGYTNGCNTGGYTNGGNCARGCNTTYGTNTGYYTNTCNTCNYTN CARGCNYTNMGNGTNGTNYTN---GTNGGNCCNTAYMGNGTNYTNATGGCNGCNATHGCN GTNGCNYTNGGNATGTGGTTYCARTCNGTNGCNTCNGARGCNGTNAAYAGYTGGTTYCAY TCNTTYTAYATGYTNCAYGTNACNYTNAARGARGGNMGNGAYYTNGTNGTNMGNGAYAGY TGYGGNACNAGYGAYCCNTAYGTNAARTTYAARTAYGGNGGNAARCARGTNCAYAARAGY MGNACNATHYTNAARAAYYTNAAYCCNAARTGGGAYGARCARTTYATHATHCCNGTNGAY GAYGTNACNAARCCNYTNAAYGTNAARGTNTAYGAYTAYGAYMGNGCNTGGAAYGAYGAY CCNATGGGNTCNGCNGAYATHGAYYTNACNACNYTNGARATHGAYAARGARGTNGAYYTN AARYTNYTNYTNAGYGARMGNGGNAARTCNGAYTAYATGGGNTAYYTNYTNGTNTCNTGY AAYYTNGTNCCNAARTCNGARGARGAYMGNGAYCARTTYTTYMGNMGNTCNGTNMGNTCN ACNGAYTCNGCNAARAARGTNAARATGCARTCNTGG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYGGNTAYAARYTNAARGTNGARAAYCCNCAYCARCCNATG AARTGYYTNACNGAYATHATGAAYTTYTTYGTNCARACNTCNGGNGCNYTNACNACNAAR CCNATGACNTGYAAYATHYTNCAYAARYTNGGNATHGGNTTYGCNATHGTNTTYYTNGTN AARAAYGCNAAYGGNGGNMGNYTNGCNYTNAARMGNATGTAYGTNAAYAAYGAYAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGCNTCNTCN AAYGTNTCNMGNACNTTYGTNAARTCNYTNAARGGNMGNGCNTTY---TCNGCNGCNGCN GCNCARGCNGAR---MGNGCNCAYGCNGAYAGYACNCCNAARTGYTCNGTNAARAARYTN AAYAAYGGNATGTCNGTNGGNGTNATHCCNTCNAAYTCNCCNGTNGCNMGNGTNGCNGTN GTNGCNAAYGCNGGNTCNMGNTTYGARACNGGNGAYAAYYTNGGNGTNTCNCAYYTNYTN MGNATGTCNGCNMGNYTNMGNACNCARGGNATGACNAGYYTNAAYATGACNMGNACNATH CARCARYTNGGNGGNGAYATHACNATHATGGGNACNMGNGARTAYATHTAYTTYAARAGY AAYGTNACNMGNAAYTCNGCNGAYAARGCNATHAARATHYTNGARGARYTNACNACNAAR CARGCNTAYCARGCNTGGGARYTNACNGAYGTNCARAAYGAYCARAAYGCNATGGCNYTN GAYYTNGCNYTNTAYCARACNMGNCAYGAYATHMGNGCNATGGARYTNYTNCAYACNGCN GCNTTYMGNAAYACNYTNGGNAAYTCNYTNTAYGCNCCNGARCAYATGATHGGNTCNTAY ACNCCNGAYCARGTNATGCARTAYGTNAARACNCAYTTYAGYGGNGGNMGNYTNGCNYTN GTNGGNATHGGNGTNGAYGGNGCNGTNYTNGARGAYYTNGCNTCNTCNTTYGARCCNTAY GCNAAYGCNGGNGTNCCNGTNCARAARGCNTCNTAYCAYAGYGGNGGNGARATHMGNGAR AAYACNGGNGGNGARGTNTCNTTYGTNGCNGTNGGNTTYGGNGGNCCNAGYYTNACNAGY AARGAYYTNYTNGCNTCNGARGTNYTNMGNCAYATHYTNGGNACNGGNCCNCAYGTNAAR TAYAGYAAYGGNACNGTNGGNGCNCARYTNGCNAARGCNGCNGAYGGNGCNACNGAYGCN CCNTTYCAYGTNTCNGGNATGAAYGCNAAYTAYAGYGAYAAYGGNYTNTTYGGNTTYACN GCNGTNGCNCAYTCNTCNAAYATHGARAARGTNYTNCARGCNGCNGGNAAYCARTTYAAR GGNYTNYTNGGNGGNAGYATHACNGAYCARGAYGTNGCNAARGGNAARAAYCARYTNAAR GCNGARATHTGYATGCARTTYGARAAYCCNGAYGTNYTNYTNAAYTGGYTNGGNGARCAR GCNATGAAYAGYGARGAYGTNATHAGYCCNGARGAYATHTAYAARATGGTNGAYAAYATH ACNGTNAAYGAYGTNAARTCNGTNGCNAARAGYATHYTNCARGCNAARCCNAGYATGGCN TCNACNGGNAAYATHGCNAAYGTNCCNTAYYTNGAYAARYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TTYATHGCNAARGCNATHCAYTAYGGNTTYTGYYTN GCNGTNTTYYTNATHACNATHTCNACNGTNGGNAAYTTYCARYTNTTYGTNTCNCARCAR ACNYTNAARTAYTGGGAYGGNGAYGCNTCNGTNATHGGNTGYTTYYTNTGGGAYTTYGCN YTNGTNTGYYTNTTYATHGGNCARCAYTCNYTNATGGCNACNCCNTGGTTYAARAGYGGN YTNMGNTCNTGYYTNMGNACNACNGCNTCNGARMGNYTNGTNTAYYTNTGYATGACNTGY ATHACNYTNATGGTNATGATHGTNTAYTGGCAYAGYATHCCNCARGTNTAYYTNTGGTAY ATHGAYACNCAYGAYMGNCCNYTNYTNTGGGCNTTYTTYYTNYTNTGYCAYTTYGTNGGN TGGYTNYTNATHGGNYTNGARGTNACNYTNATGGAYATHGGNGARYTNYTNGGNTTYAAY CARGTNTAYAAYTTYCAYAAYTGYYTNACNCCNCCNYTNYTNAARAARAARGARGCNACN YTNMGNCARATHTAYTCNAGYATGMGNCAYCCNGGNGTNGTNATHYTNTCNATHYTNYTN TGGTTYTAYCCNYTNATGACNYTNGAYMGNGTNTTYYTNGCNTCNGTNTTYACNTCNTAY ACNGCNTGGMGNCAYAGYYTNGARGAYGTNCAYGTNGARTAYGCNAARAARACNTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGNGCNTCNTCNGCNYTNMGNTGYATGTCNCARAAYMGNGAYAGYTGY GGNATGGGNAGYMGNGCNGGNTCNTCNGTNACNYTNGAYMGNTCNYTNMGNMGNGCNMGN MGNTAYMGNGARACNTGYCAYTCNGCNCCNGGNACNYTNCARMGNCARCAYMGNAAYMGN CAY------------------------------TCNCCNCCNCCNCCNGCNTAYGGNGAY CAYCARTCNTCNCCNCCNCCNCCNCCNTAYAAYTCNGTNCAYGAYGAYYTNGCNYTNGGN TCNGAYTTYTCNCCNAGYGCNGAYATGCARACNAGYATHCARTCNGAYTAYAAYCCNGAR MGNAAYGGNAAYGGNGCNCARCCNYTNYTNAGYCAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNTCNCCNTCNCARGCNTCNCCNGTNYTNYTNGGNCAYYTNCARACNGGN GTNCCNCAYCARGCNTTYCARAAYCARGTNYTNTCNAAYAGYATHTCNTCNACNCARTCN GAYACNGCNACNGTNTCNACNAAYTAYGARGARCCNGTNTTYTCNTAYAGYTGYYTNATH GCNYTNGCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GCNATGGARMGNTTY TAYTCNYTNCAYAARCARACNYTNTTYGAYTAYATGACNAARGGNTCNATHGAYGAYGAY CARACNACNTTYGTNGAYTGYGTNYTNAARGAYMGNGAYAAYTTYMGNCCNGTNYTNGGN GAYTGGTAYGAYYTNYTNAAR---YTNTTYMGNTCNGTNCAYAGYGTNATHAAYMGNACN CCNGCNMGNYTNYTNCAYGARATHGTNYTNGTNGAYGAYAARTCNGARYTNCCNCAYYTN CAYGARMGNYTNGAYGARGARATHAARAARTAYCARGGNAARGTNAARYTNGTNMGNAAY AGYCARMGNGARGGNYTNATHMGNGCNMGNAAYAAYGGNGCNATHGCNGCNTCNGGNGAY GTNGTNGTNTTYYTNGAYGCNCAYTGYGARGTNGGNCCNAAYTGGYTNCCNCCNYTNYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TGGMGNACNAARTCNCARAARYTNGARAARGTNATHAARACN YTNTCNAAYCAYTGYGTNMGNGTNGTNGARCAYCAYGARAAYYTNYTNGTNAARTTYAAR AARAAYCARGAYCARTAYGARAARYTNMGNGCNAARTGYAARGARMGNGGNGARCARATH AARCARGCNMGNGARGTNYTNGTNCCNGTNTCNAAYGARYTNAARATGYTNMGNGARAAR TAYGARYTNGCNATHMGNTGYCARGTNGARGCNGARTCNTTYGCNATHGARACNACNAAY CARAAYAARAARYTNAARMGNCARAGYCARAARATHATGGCNAAYYTNGGNAAYGTNAAY ATHGTNGAYATHAAYATHGAYGAYGAYGTNGARCARGAYGARGARGARAARAARTAYATH GARAARYTNGGNCARCARATHGAYGARYTNGARGTNGCNAARAGYACNYTNAARATHCAR GTNCARGARYTNACNGARAGYYTNGARGAYGARAARGARGCNAAYGGNMGNYTNACNGAY MGNGTNGAYATHATGAARGGNGARYTNCARCARGCNAARACNACNATHCARGARCARTCN GARYTNYTNCARAARGTNGCNGTNACNTCNGARATGGCNTAYAARGARTAYCARGAYATG GARCARACNTAYMGNAARGARTAYATGGTNMGNAAYGARGCNGARMGNTTYGCNAARAAR YTNTGYACNGARMGNGAYCARGCNMGNMGNGARAGYTCNATGGCNYTNAGYCARGTNGCN GGNAAYAARAARYTNATGGARGCNATGGTNGARATHCARGARYTNAAYGCNAARGCNATH GARATGAARGAYGAYTTYGAYAARCARATHCAYGAYYTNCARGARGARYTNAARGCNACN AARGARYTNTAYAAYGCNGARCAYYTNGARGCNGARAAYGARGARYTNAAYGTNGARAAR GARACNYTNCARGARMGNYTNGARAARAARGARATGGARATHACNGARYTNMGNACNAAR TAYGCNGAYYTNGARAARATHTAYAARGARYTNGARACNAARTAYGARMGNGCNYTN--- ---CCNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNACNTTYAARGTNGGNGGN TTYYTNCARAARATHGTNGGNMGNAARGGNCAYMGNGARMGNGCNAARGARCARYTNAAR AARGGNGGNGTNTCNATHGAYAGYAAYCAYGCNAARGCNGTNGARGARATGATGCARMGN ATHAARAAYGGNAAYGTNGGNYTNMGNCCNGTNYTNCARMGNMGNGCN---------CAR TCNYTNCCNGAYAARGARGARCCNAGYGCNATGAAYGARYTNCARGGNYTNYTNACNAAR ATGAARAARGCNMGNAGYGARGAYGAYYTNTCNGTNTTYGGNGAYACNGGNGTNAGYGAY ---GAYTCNGARYTNGGNAARATHYTNAARMGN---MGNCAR------------------ ---------CARATGAGYCARGGNCCNCCNGARCCNGTNMGNAGY--------------- ------MGNCCNGTNCCNGCNCCNMGNAARYTNTCNACNATHCARGAYGAYTCNGARGAR TGYGGNGARCCNMGNACNGAYCCNGAYTTYGTNGCNATGGARGGNTTYGTNAAYAGYGTN AAYCARYTNMGNGGNMGNACNGGNATHAAYTAYGGNTAYYTNGTNATHGAYGAYTGYTAY AGYCCNGCNMGNGCNTCNAARYTNATGYTNGAYGTNYTNMGNGARGAYGTNCARATHACN GAYGARGARACNGGNGARGTNYTNGAYCCNGAYACNATHTGGGTNGTNATHGGNCCNYTN ACNAGYTCNAAYACNATGGCNYTNYTNTCNTTYYTNAARGARTTYCAYATHCCNGTNATH TCNTAYCARGCNACNACNCCNGTNYTNAGYAAYAARYTNYTNTAYCCNTAYTTYTCNMGN ACNYTNCCNAGYGAYATHYTNCAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CARGCNATGGGNTCNYTNTCNGCNGCNGCN YTNTCNTCNACNATHCARCARGTNTCNTCNAARATGAAYGGNCCNATGATHCCNTCNTCN AGYAAYGTNAAYGGNGGNGGNGAYGGNGGNAAYGCNGGNATHCARMGNTGGTTYGGNTCN GAYATHYTNAARACNCARYTNCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TCN GGNGGNAGYGTNGAYAAYAGYTGGAARCARCAYGAYATGTAYCAYTAYTAYACNGARCAR GAYYTNAAYTCNGARAAYAAYTAYGCNTGGTTYMGNGAYCAYGGNAAYTTYCARGAYACN CARAGYTCNTTYYTNACNCCNAARAARAARGCNAGYAARCARATHMGNMGNTCNTCNCCN MGNACNAARCAYTTYAAYMGNAARTCNTCNTCNAGYCAYTCN---------CCNCCNAAR GCNGTNGGNCARACNACNTCNACNTTYAARCAYCCNYTNYTNYTNCAYGGNAGYAGYACN CARCAYAARMGNCCNTAYTCNTCNYTNTCNGCNTAYCCNCARTCNTCNAARCAYGGNGTN GCNAARAAYAGYTCNGGNGGNCARAGYAARAARYTNYTNACNTCNTCNYTNACNCCNGAR ATGGAYCARCCNYTNTCNTCNTAYAGYGGNATHAGYMGNMGNCCNAGYTCNCARTCNTCN CAYGGNAGYACNAGYMGNAARMGNCCNGCNTCNYTNAGYMGNCCNTTYAARTTYCCNMGN ACNAGYACNCCNTCNCCNAAYCARACNYTNCCNTCNTCNYTNTCNGCNTCNTCNTTYTCN YTNTCNTCNYTNAARCCNGARATHAARCCNGAYTGYGARGCNTCNCCNATHTCNAGYMGN TCNTTYTCNTCNCAYAARMGNGTNCCNTTYACNACNGTNYTNGAYATGCCNGARTCNGGN GTNMGNMGNTCNCCNMGNAARYTN---------------------TCNCARCCNGGNTTY ATGAAYACNYTNAARGAYCCNAARTCNGARGARTCNAGYCAYTCNAAYGCNTCNGARTCN AARCCNGCNAGY---------------------------------CARAARATGAARMGN TCNGARMGNCAYATGATGMGNYTNAARAGYATHATHACNAARGTNYTNACNGARAARGGN GTNGARAARAAYGAYCCNATHTAYCARGCNTGYTCNAARAAYYTNYTNAAYGTNAGYATH GTNYTNYTNAARAGYYTNCCNAAYTCNMGNAAYYTNACNGAYGARATGAARTCNGTNGTN TAYGGNCARGTNCARCARATHATHAAYYTNGARAARMGNMGNTCNGGNATHGCNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TTYCAYGAR--------------------------------------------- ------------------------TTYYTNCARATGTCNYTNTGGGGNAAYAARTGYGAY YTNTCNATGTCNGCNGGNCAYGAYGCNAAYCCNACNGARGAYCCNYTNCAYCARYTNGTN MGNYTNAARCCNAAYATHYTNGTNGAYCAYTCNGAYGGNATHYTNATGYTNYTNMGNGAY AARCARAARAGY---TCNGGNAARGGNGCNCARATHTCNTAYGTNYTNGAYAAYGCNGGN TTYGARTTYGTNACNGAYYTNTGYYTNGCNGARTTYYTNYTNTCNACNGGNYTNGCNTCN AGYATHCAYTTYCAYGGNAARGCNTTYCCNTGGTAYGTNTCNGAYGTNACNGARGCNGAY GTNAGYTGGGTNTTYCARCARATGTCNTCNACNAAYAAYGARGCNATHMGNGARYTNAAY CARATHTGGMGNAARMGNTCNCARGAYGGNACNATGACNTTYCARTAYCAYTCNTTYTGG ACNYTNCCNCAYTCNTTYTAYAARATGCARTCNYTNTGYCCNGAYYTNCAYTCNAARYTN GCNCARAGYGAYYTNGCNATHTTYAARGGNGAYYTNAAYTAYMGNAARYTNGTNTCNGAY YTNAARTGGGAYACNACNACNAGYTTYTCNCAYAGYYTNCARGGNTTYCAYCCNACNGCN GTNTGYTCNYTNMGNACNGTNAARGCNGAYGTNGTNGTNGGNYTNGARCAYGGNAARGCN GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AARAAYTTYATH GGNACNTCNGGNCARGTNAARCARGTNACNGARATGAARAAYYTNATHTGGTCNGTNTCN AARGGNYTNGARTCNACNCARACNAARGTNAAYAARAGYGARGCNGTNYTNAGYYTNATG GARGCNGARGTNAAYGCNYTNMGNGAYMGNGTNGCNYTNYTNGARAARGARGARATGGAR MGNGCNTTYCAYAARGCNGARYTNCARAARCARMGNGARGARGARMGNAARCARMGNGAR AARACNCARATHYTNATHTTYCCNCCNTGYTTYCCNTAYMGNMGNAARMGNAGYMGNNNN MGNAGYMGNAGYMGNGARAARMGNMGNTCNMGNAGYMGNGAYMGNMGNTCNMGNAGYMGN AGYMGNGARMGNMGNMGNMGNGARGAYMGNGARAARGGNMGN---MGNMGNAGYMGNAGY AARAGYMGNGAYMGNAARMGN---AGYAGYMGNAGYMGNAGYMGNGARMGNMGNMGNAGY MGNAGYMGNAGYMGNGARMGNMGNMGNMGNAGYMGNTCNCCNMGNMGNMGNTAYAGYMGN AGYCCNGTNMGN---GARMGNYTNCCNGARYTNACNGTNGARGARMGNGAYGTNMGNACN ATHTTYTGYATGCARYTNTCNGCNMGNATHMGNCCNMGNGAYYTNGARGARTTYTTYTCN TCNGTNGGNAARGTNMGNGAYGTNMGNYTNATHACNGAYAAYAARACNMGNMGNTCNAAR GGNATHTCNTAYGTNGARTTYGCNGAYCCNGARTCNGTNACNYTNGCNATGGGNYTNACN GGNCARAARYTNYTNGGNGTNCCNATHATGGTNCARCCNTCNCARGCNGARAARAAYMGN GCNCARCCNGCNACNCARGCNCCNGCNCARAARCAR---GCNCCNGARGGNCCNYTNMGN YTNTAYGTNGGNTCNYTNCAYTTYAAYATHAAYGARGAYATGYTNMGNGGNATHTTYGAR CCNTTYGGNAARATHGTNGAYATHAARATHATGMGNGAYCAYGAYACNCARMGNTCNYTN GGNTTYGGNTTYATHAGYTTYGCNAAYGCNGAYGAYGCNAARAARGCNYTNGAYCARYTN AAYGGNTTYGARYTNGCNGGNMGNCCNATGAARGTNGGNCAYGTNACNGARMGNACNGGN GARCARGGNCARGGN------GCNCARAAYGGNGTNGGNGGNCARYTNGAYACNGAYGAR ATGGAYMGNGCNGGNATHGAYYTNGGNGCNACNGGNMGNYTNCARYTNATGGCNAARYTN GCNGARGGNACNGGNTTYCARATHCCNCARTAYGCNGCNAGYGCNYTNAAYAAYATGTCN ---ACNCCNGCNGCNGTNCCNGGNGTNCCNACNGCNGCNGCNGCNGTNGCNGCNCCNGCN GCNCCNATHGTNGCNAAYTCNATGGCNATHCCNCCNGCNGTNCCNACNACNGTNGCNGCN CCNGCNACNACNAAYACNCCNCCNATHGCNACNCARTGYTTYATGYTNTCNAAYATGTTY GAYCCNACNTCNGARCCNMGNYTNACNTGGGAYCARGARGTNMGNGAYGAYGTNATHGAY GARTGYAAYAARCAYGGNGGNGTNYTNCAYATHTAYGTNGAYAARAAYTCNCCNCARGGN AAYGTNTAYGTNAARTGYCCNAGYATHTCNGCNGCNGTNGCNTCNGTNAAYTCNYTNCAY GGNMGNTAYTTYGCNGGNMGNGTNATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYATGTTYTGGTAYYTNTTYYTNGAYAARTTYCARCCNAGY CARAAYTAYCARGCNAARYTNTTYAAYMGNATHTCNCAYAAYTAYGTNAARYTNATGATG ATGACNTCNGAYCCNATHGCNAARGAYACNTTYTTYAARGAYTAYCCNAARYTNATGTCN CARGGNGTNTAYGCNTCNTTYTGYTTYTGYTTYCCNGAYTCNTAYMGNCARTTYGGNGAR AAYTTYAARGAYCARYTNGTNTAYYTNGTNTAYGGNTGGATGGCNGGNATHMGNCCNGCN CCNMGNAGYTGGATHACNTGGGAYATGACNCAYYTNGARCCNCCNAAYYTNAARATGMGN GARGARYTNATGCARAARAARAAYAGYAARAARATGACNTCNTTYATHGAYTTYGAYTAY YTNGAYTCNYTNATHTCNACNAAYGCNAGYCARTAYGCNTCNACNATGTCNYTNGCNCAR TCNACNTCNAARTCNTCNACNACNTCNATHYTNGGN---CCNGCNMGNAARTCNMGNATG CAYGCNMGNATHAGYAAR---CARCAYAARCCNTTYATHMGNACNTCNTCNCCNAAYAAR ACNCAYTCNCCNAAYTCNTCNCARGAYTCNAAYYTNATHGAYGTNGTNGCNGAYGCNCAR GCNAGYCCNMGNTGYAARGGNMGNGARAGYAARMGNGGNAGYGGNGAYTCNYTNATHCCN GCNAARGAYYTNAARMGNCARAGYGAYGCNYTNACNCCNATHMGNGARATGACNAGYGAR GAYGARGARGARGAYTTYGGNAARAARTTYTCNCARGTNTCNATGAGYCARATHMGNGAR AGYMGNAAYAARAARCARTTYGCNATGGARTCNCAYCCNATGGGNAARGGNTGYGAYTTY GTNMGNACNGCNTTYAAYGTNGARGGNMGNAGYCCNYTNGTNGCNCAYTTYYTNAAYATG AARGGNYTNACNCARGAYGTNGGNCARAAYATHTGGATHCARMGNGTNGARGTNGAYAAY YTNCCNCCNYTNGAYGCNACNACNTAYAARGAYGTNATHAGYGARTCNTCNAARACNATH AARAARYTNGARTGYGGNTTYCARGAYYTNTAYGCNAARAAYTAYAARCAYAGYCARYTN TTYATGAARCARCARCARAARATGYTNMGNGAYCAYATGCAYAARCARTCNGCNYTNYTN GCNAAYMGNGARGARGTNAARGTNYTNTGYGAYYTNATHATHYTNGARCARMGNAARAGY CARGAYTCNGTNTCNGCNGGNGCNTCNGCNGCNATHGARGCNGCNYTNATGGCNCARGAR GTNCCNGARGARGARAARGTNTTYCCNGARGAYTTYATHTCNGAYGARGARAARCARGTN CAYTCNGAYTTYTTYGAYGGNMGNCCNCCNAARACNCCNGARMGNTAYYTNAARATHMGN AGYTAYATHATHGAYTGYTGGGTNAARAAYAARCCNATHTAYYTNAAYAARACNTCNGTN MGNCCNGGNYTNAARAAYTGYGGNGAYGTNAAYTGYATHGGNMGNATHCAYTCNTAYYTN GARTGYGTNGGNGCNATHAAYTTYGGNTGYGARCARGCNGCNTAYMGNAAYCCNCARMGN CARGTNAAYGGNGGNCCNAAYAGYMGNGCNAARGGNATGAAYAARGARYTNATGGCNTCN TTYCCNGTNGTNAARTCNGARTTYATGMGNCCNMGNAARMGNMGNATHMGNGAYGARAGY GGNYTNTGGGTNGAYGARAARGARYTNGARGGNAARACNATHGAYCAYAAYGTNYTNGAR AARAARAARATHCARGTNMGNAARATHMGNAGYGCNAARCARGTNTAYAAYCCNTTYAAR YTNGTNCCNTGYYTNTCNTTYAGYGAYGARCAYAARGARCCNTAYAARATHGARATHTTY AAYACNGCNYTNTCNATHATGGAYATHCAYTCNCAYATHTCNAARACNGARGTNATHGGN ATGYTNGGNGGNMGNTTYAAYGAYGAYACNGARTGYYTNACNATHAGYATGGCNGTNCCN TGYAARAGYATGAGYACNGGNATGCARTGYGARATGGAYCCNGTNTCNCARACNYTNGCN AGYGARCARATHGARGAYGTNGGNATGTCNGTNGTNGGNTGGTAYCAYTCNCAYCCNACN TTYNNNCCNGAYCCNTCNGTNMGNGAYATHGARACNCARCARAARTTYCARTAYTGGTTY TCNAARGGNGGNAAYCAYTTYGTNGGNATGATHGTNAGYCCNTAYAAYTCNTCNTGYCAY TCNACNYTNTCNGAYATHMGNTGYYTNACNATHAGYGAYGARCAYAGYTCNGARTTYYTN TGYAAYATHCCNTAYAARTTYGARTAYCARATHGTNTAYAARGAYAAYYTNMGNGARATH YTNGGNCCNGCNAGYGARYTNGCNGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATHCARTGYTCN CAYGGNMGNTGYACNACNTCNTTYCAYGTNTCNTGYGCNATHATGGCNGGNATHAARTTY GARATGAGYGAYTGGCCNGTNCCNATHTAYATHTCNTGYMGNAARCAYATHACNACNMGN CARAARGCNGGNATHMGNCARGAYATGCCNGAYYTNGARYTNATGAGYMGNGCNYTNGCN AARCAYAARAAYAARMGNTTYTAYTGGGCNAAYGTNGTNMGNGTNGAYAARAARMGNYTN TAYGARGTNGAYTTYGAYGAYGGNTCNTTYAGYGARGAYYTNYTNCCNGARGAYATHGAR AGYMGNGAYTGYYTNMGNGAYGGNCCNCCNATGAARGGNGARCAYGTNYTNATHAARTGG GARGAYGGNAGYYTNTAYGGNGCNACNTTYMGNAARGTNAAYAAYCARGAYGTNTAYACN GTNGARTTYGARGAYGGNTCNYTNACNCARGCNMGNMGNAAYGARYTNTGGGGNGARGCN GARGARATHCCNMGNCAYGTNMGNAAYMGNATGTCNCARGCNACNGARCARMGNTTYGAY ATGTCNGAR---AARGARGCNCAYGAYGGNMGNMGNAAYAARAARAARGTNGAYTAYYTN AARATGYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNGGNGTNGTNCARTTYACNATGGGNYTNYTNAARYTNGGNATHYTNGTN AGYTAYATHTCNTAYCCNGTNATHAAYGCNTTYACNTCNGCNGCNGCNATHACNATHGCN TTYGGNCARATHAARAAYATHYTNGGNYTNACNGAYATHGAYMGNGARTTYYTNCAYATG GTNTAYGARACNTTYGARAARATHCCNGARACNATGGCNGARCCNMGNGTNCARAARYTN YTNGAYATHCAYATGTCNYTNGTNTAYGARGARAARACNAARAARATHACNTGYAGYYTN ACNAAYCAYCARATGCCNGCNAARCCNGARGCNATHGARAGYTAYGTNAAYGGNAARAAR TAYAARMGNYTNGCNGARATGAAYTCNTTYTCNTAYGARGAYCAYAARGARCAYATHGTN CARAAYAARAARAARCAR------AAYGARYTNTTYTGYAAYYTNACNYTNMGNCAYYTN GARAARACNGCNAAYGCNATHCARMGNCAYATHACNGGNMGNAARTAYAARAAYGCNYTN GCNAARTGGAARGAYTGYCARMGNAARGGNACNAARTTYACNCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNYTNGCNGCNTTYMGNAGYYTNCAYMGNGCNMGNMGN GARGTNTTYGCNGGNGAYAARMGNGCNYTNAAYGARGTNMGNAAYCARATHAAYTCNCAR TTYMGNGARAARYTNCARGARACNGAYGGNTCNAARATHGARGARAAYTTYGTNYTNGCN AAYGAYGTNGCNTAYYTNYTNMGNTCNACNGTNGTNCARYTNAARCARAAR------GAY GAYGARACNTTYGARYTNMGNATHACNAARAAYACNCAYYTNCCNGARAAYACNCCNTTY GAYCCNACNAARGARATGCCNYTNAARCARMGNAAYAARAAYAARAAYGGNTGYGCNGAY TCNACN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR ATHGCNYTNTCNGCNMGNAGYYTNYTNGARYTNGAYCARTAYYTNAARGAYATGTAYCCN GAYTTYATHAARATHTGYAAYATHTGYAGYAARYTNTGYATGCARGGNGARYTNTGYACN AGYTGYGGNATGAARATHCAYTTYMGNTGYGCNMGNACNTTYTTYTCNAARCARACN--- ACNAARAARTGYCCNTCN------TGYAARTCNACNTGGATHGAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNCARCAYACNTTYCAYGAYYTNYTNTCNTCNYTN YTNGARTGYTAYAARGARTCNGAYTGGYTNTCNATHGTNCCNTCNYTNTGYMGNMGNYTN GCNACNATHCCNCAYCAYCAYCAYAGYTGYGTNTAYYTNGTNGARYTNYTNCCNYTNAGY GGNMGNGGNAAYTAYYTNCARATHMGNYTNAGYTTYYTNYTNYTNTGYTCNACNYTNGAY YTNGARAARTAYCARYTNTCNGTNYTNCARYTNGAYTCNATHTCNCCNTCNMGNATHACN TGYYTNGGNGARCCNCCNGARTCNCARCARCCNACNTCNMGNYTNTAYTCNAAYYTNCAY CARYTNATHAARGARGAYATHAAYMGNYTNAAYTCNGCNATHATHYTNYTNGAYMGNGCN GTNGGNGAYGARACNAAYMGNAARGCNCARCCNMGNGARGARYTNGAYTAYYTNACNAAY CARGTNAARATGGTNATHAARGTNATHMGNGAYAGYATHAAYACNYTNGAYYTNTCNAAR GTNAARGAYMGNATGACN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GGNGCNGGNAARACNTTYACN ATGACNGGNGCNACNGARAGYTAYMGNCAYMGNGGNYTNATHCCNMGNGCNATHTCNCAR YTNTTYMGNCARATHGARGAYMGNYTNGARTAYAGYATHACNGTNMGNGCNTCNTAYATG GARATHTAYAAYGARCARATGTTYGAYYTNYTNGGNACNTTYCCNGARGCNTCNTGG--- ---TCNGGNAARGAYATHAAYGCNAGYCCNGAYCCNATGGTNATHTCNGARAAYCARGGN GGNGTNTTYGTNAARGGNYTNTCNTGYCAYYTNGCNCARAAYGARGARGARGCNYTNAAY YTNYTNTTYGARGGNGARACNAAYMGNTCNATHGCNGCNCAYTCNYTNAAYAARCAYTCN TCNMGNTCNCAYTGYATHTTYACNYTNTAYATHGARTCNMGNTCNMGNGTNCARTCNAAY GCNAARTAYACNGTNTCNAARYTNAAYTTYGTNGAYYTNGCNGGNTCNGARMGNYTNAGY AARACNAARTCNGARGGNAARACNAARGARGARGCNATGTAYATHAAYAARTCNYTNTCN TTYYTNGARCARGTNGTNATHGCNYTNGCNTCNAARACNMGNGAYCAYGTNCCNTTYMGN CARTCNAARYTNACNCAYTTYYTNAARGAYTCNATHGGNGGNAAYTGYAAYACNGTNYTN ATHGCNAAYATGTGGGCNGARAARCCNCARYTNGARGARACNGTNTCNACNYTNMGNTTY GCNACNMGNATGATGTGYGTNGCNAGYGARCCNGCNGTNAAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNTCNTCNTCNTTYGARTGGACNATHCAYAAY TAYTTYCARAARMGNGARGARGARGCNTGGGGNAARGARTCNTGYYTNATHTCNCCNTCN TTYTAYACNGARCARGAYGGNTAYAARGCNCARGTNGARGTNTAYYTNAAYGGNAAYGGN TCNGGNAARGGNAARTGYATGTCNGTNTTYYTNAGYGTNATHAARGGNCARTAYGAYGGN TAYMGNCARTGGCCNGTNAARTTYTCNATHCARTTYATHGTNYTNAAYCARGCNGAYTCN GAYGTNGAYTCNYTNATGCAY------------GARTCNGTNTTYGARTAYAAYAAYCCN ---TCNGGNAARGARGARTGYGAYAAYACNTGGGGNGTNATHGARTTYGTNCCNCAYTCN GTNATHAAYGARMGNAAYTAYATHAARAAYAAYGCNATHAARYTNAARYTNMGNATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNACNATGGAYTTYCCN AARAAYGARCCNGCNCCNCARGAYACNGARATHYTNGARGARYTNYTNYTNAGYYTNGTN GGNGAYCAYGAYYTNATHCARGAYGTNYTNTAYTCN---TCNACNACN---AARAARYTN GTNMGNTTYAARGAYCAYATHCAYMGNAARGARYTNGARAARYTNTGYCCNAARCCNAGY GTNYTNATGGARGCNGARCCNACNGGNYTNGTNAARGGNGTNGGNGTNACNYTNAARGGN TGYCAYGCNAAYGGNTGYGTNGAYGARGARGGNAAYGTNTAYGAYTTYGTNTCNMGNTAY TGGGCNCCNTGGAAYGGNATHCCNGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TAYTTYCCNAARGGNGGNCAYGARGGNCAYYTNCCN AARYTNATHGARAARTGYYTNACNAARTTYCARCCNGARGCNAARTAYGCNAAYGAYYTN MGNTTYATHAARYTNTGGATHGTNTAYTCNAAYTTYATHGAYACNCCNACNGAYGTNTTY TCNTAYATGTTYGAYAAYGGNATHGGNACNAARGTNTCNCARYTNTAYATHGARTGGGCN ATHAARYTNGARATGGCNGGNAAYATGAARAARGCNGAYAGYATHTAYACNGARGGNATH AAYMGNATGGCNGARCCNAARGAYYTNYTNGTNCARAARCARGARCARTTYCARCAYMGN YTNACNAARAAYATHACNYTNCARATGACNGARCARACNAARCCNGCNATGGARAGYGAR CCNGARGARAARMGNCARGTNYTNACNMGNYTNAARCCNGTNGGNGGNGGNCAYAARGTN GGNACNACNMGNACNGGNGCNGTNAGYYTNGGNTCNGCNGGNMGNYTNAARGAYGAYMGN MGNTCNGCNCCNAARCARATHCCNTCNCARMGNTTYACNGTNTTYAAYGAYGARAAYGTN GCNCCNCAYYTNGTNCARACNAAYGARTGGGTNTCNATGCCNTAYYTNTCNAGYYTNCAR CCNCCNATHTCNTCNTAYAARAAYTTYCARAARATHGAYGARGAYGTNACNACNGTNTCN GARAARGAYATHATHGCNGTNGAYAARTGYYTNGGNGARGGNGGNTAYGCNCARGTNTAY AARATGTAYAARGAYTTYTTYGCNATGAARGTNCARAARCCNCCNTGYCAYTGGGARTTY TAYATHTCNTGYGARATHCARAARMGNYTNACNGCNYTNAARGCNCCNATGGAYGTNMGN CCNTCNATHATGAGYATHGAYGARGGNTAYTTYAAYAAYACNYTNAGYATHYTNACNATG AAYYTNYTNGARCAYGGNTCNYTNYTNAAYGTNGTNAAYYTNTAYAARTCNGAYCCNAAR YTNATGGGNCARGTNGARCCNTTYGTNTGYYTNGTNACNGTNGARYTNYTNCAYYTNTTY GARCARYTNCAYAARTGYGAYATHATHCAYGGNGAYGTNAARCCNGAYAAYTTYYTNYTN ATHGAYYTNCCNATHGTNTGYGARAGYTCNAAYCCNGCNGAYGTNTTYGGNTCNAARTCN MGNGTNTTYTGYYTNACNGAYTTYGGNCARACNATHGAYATGCAYATGTTYCCNGCNGGN ACNAAYTTYMGNACNAARACNAAYACNGAYGGNTTYGARTGYATHGARATGMGNACNGAY CARCCNTGGACNTAYCARACNGAYYTNTTYGGNYTNGCNGGNACNATHCAYGTNATGYTN TTYGGNTCNTAYATGAARGTNTTYGTNGARAARGGNGTNTGGAARATHACNGGNAAYTTY GTNMGNAARTGGAAYGTNCCNYTNTGGAARAARYTNTTYCAYCARYTNYTNAAYATHCCN TCNTGYGAYAAYYTNCCNGAYYTNGTNTCNYTNMGNGTNGARTTYGARGARTAYTTYTGY TCNAGYYTNACNACNGTNTAYAAYGARTGG---------------ATGGGNAAYGGNATG AAYAARATHYTNCCNGGNYTNTTYGTNGGNAAYTTYMGNGAYGCNAARGAYCCNMGNCAR YTNGARGARAAYAAYATHACNCAYATHYTNTCNATHCAYGAYAAYGCNAARAARATHYTN AARGAYAARGARTAYYTNTGYATHGAYGCNGCNGAYTCNCCNGAYCARGAYYTNACNAAR TTYTTYCCNCARATHAAYAARTTYATHCAYAARGCNMGNYTNGARGGNGGNGCNGTNYTN GTNCAYTGYYTNGCNGGNGTNTCNMGNAGYGTNACNGTNACNACNGCNTAYATHATGACN GTNACNGARYTNGGNTGGMGNGAYGCNYTNAAYTCNGTNMGNGGNGCNMGNAGYGTNGCN AAYCCNAAYTTYGGNTTYCARAARCARYTNCARAAYTAYGAYACNGAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARTTYGGNAGYGTNGCNYTNCARGARAARYTNAAYATGGAYTCNTTYGCNMGNYTNTAY GARTAYTAYTCNGARTAYACNTCNCAYTTYGAYGAYCCNYTNGAYAARAAYYTNGGNGTN MGNTCNYTNAGYCAYATGATHAARYTNYTNCARAAYAAYGTNATGACNAARAARAGYAAR AAYGTNGARYTNYTNCAYGGNGCNGCNGARGTNACNMGNGCNYTNMGNGGNYTNMGNGTN ACNTTYTGYAARAGYGGNAARGAYMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNAARTCNGARCAYTGYAARGTNGARGAR YTNGCNMGNGCNAARTGGATHTGYYTNAAYAARATHACNTAYAARGAYCCNCAYGGNGTN GARMGNATHTGGGARGGNGTNTCNMGNACNACNAARAAYGCNGGNGARGCNGAYGCNGTN GGNATGGTNGCNATGTTYCARGAYCCNATHACNGAYYTNYTNAGYATHATHYTNATHMGN CARTAYMGNCCNCCNATGGARACNTAYACNATHGARTTYCCNGCNGGNYTNATHGAYAAR GGNGARACNGCNGARATGGCNGCNGTNMGNGARATGAARGARGARACNGGNTAYGAYGTN TCNGTNGTNGAYGTNTCNCCNGGNACNTCNYTNGAYCCNGGNGTNGGNAAYACNACNYTN AARATHGTNACNTGYAARGTNGAYGCNAGYAGYMGNAAR---GARGARMGNCCNAARCCN ACNGGNGGNGAYTCNGAYGARTTYGTNCARGTNATHGTNCARCCNATGACNAAYYTNATG GARAARYTNAARGARTTYGCNGGNCARGGNGAYTGYGTNGAYTCNMGNGTNTAYTGYTGG GCN--------------------------------------------------------- ------------------------------------------------------------ ---------ATHAARGARGGNAARGCNACNYTNMGNYTNMGNGARCCNCCNTGYGAYATH GCNTTYAGYAARTCNGAYCCNTCNCARYTNAAYYTNTTYYTNMGNYTNGTNMGNTTYGCN AAYGARGGNAARGAYGTNCCNGAYAARACNYTNAGYGTNYTNGCNCCNGTNTCNGCNAAR CAYGTNGARAARCCNATHACNAARYTNGTNATHTCNMGNCCNTCNGARTAYCCNYTNTCN ATGCCNAARTCNGTNGARAARYTNACNATHAAYGARTGYYTNYTNMGNMGNGTNAGYCCN CARATHATHTCNYTNCCNGCNYTNACNGARYTNGAYYTNGGNTAYAAYCARATHTCNACN YTNCCNGARTCNYTNTCNGARGCNTCNAAYYTNAARTGYYTNYTNYTNCCNTCNAAYAAR ATHACNGTNTTYCCNCARGCNYTNYTNACNGGNAAYYTNCARAARACNYTNTGYGTNYTN GAYYTNAARCARAAYGAYATHGAYMGNYTNCCNTCNGAYATHATHAARYTNAARTCNYTN YTNTCNTTYAAYATHAGYCAYAAYCARYTNMGNTGYYTNCCNGARTCNYTNGGNATGATG GCNTCNYTNMGNAAYGTNCARATGAGYAAYAAYCAYYTNGAYTTYYTNCCNGGNAGYTTY YTNACNCAYTCNTTYGARTCNGTNGAYTTYAGYGAYAAYCCNTTYGTNGARAARAARGAR AGYAARGTNGARGARGARGARGAYGAYGARGARGAYGAYTCN------------GARGAY GAYATHGAYYTNGAYGAYYTNGAYAAYATHGAYMGNGTNYTNGARAARGCNYTNGARAAR AARMGNGARCARAARACNGARAGYAARGARGARGCNAGYATHGTNAARGCNGAYGTNCAY GCNTCNTCNAARTCNTCNTCNTCNTCNACNACNGARACNAARAARGARATGGAYMGNYTN GAYGCNGGNGAYTCNTCNACNATGAGYGARACNGAYATGAAYMGNYTNAARTAYTCNGTN AARGAYTCNGCNGARYTNGCNYTNCAYAARYTNCARTTYYTNGAYATHACNACNAARAAY YTNTCNAARYTNCARATHYTNYTNGTNGARYTNCARACNMGNTAYAAYGAYTGGCARTCN GGNGGNYTNGCNACNCCNTAYTTYCAYAARCARYTNAARTCNTCNGARGCNYTNYTNTCN CARTAYGARGARGAYGCNGTNCCNCCNGGNTGGTCNTGYCARTGGGAYMGNGCNAGYTGY MGNTAYTTYTAYMGNAAYGARAAYAGYGGNCAYACNCARTGGGARTAYCCNCARCAYGGN GGNGGNGGNACNACNGTNGCNGARTCNACNTCN---ACNACNGCNACNACNAAYTCNTCN TCNTCNAARGTNAARGGNGARGTNAARGAYACNTCNGCNGGNGGNAGYAGYAGYMGNAGY GGNMGNAGYAGYAARAARMGNMGNAGYAARGAYGARGAYMGNAGYAARMGNGAYMGNCAY AGY---AGYTCNCAYCAYCAYMGNAARAARAARMGNMGNMGNMGNGARCAYAGYAGYAGY AGY---AGYAGYAGYGARGAYGARAGYACNCAYTCNMGNCAYMGNCAYMGNGGNAARMGN AARAARMGNGGNMGNTCNGAYAARTCNCCNAGYYTNGARGTNATHGAYGGNCCNGARCCN ATHCARGTNATHGARGAYAGYCCNCCNCCNTCNGTNGCNCCNGCNGAYACNMGN------ ---GARGAYGCNMGNGGNAGYGGNGAYGAYGAYCAYAARGAYGCNTCNCAYCARCCNGGN YTNATHGCNGCNTAYGGNTCNGAYCARGAYGGNGARGAYGARGAYMGNGARGAYGTNGCN GGNGAYGGNAGYGTNCARAARGCNTGYGGNAAYGTNGCNGCNAAYGARAAYGGNATHGAY GGNGTNGARATGACNAARGAYGGNTAYGARGARGARAARCARGAYGGNGARGARGGNGCN ---AAYAGYGCNGTNATHGTNAARCCNCCNCARATHATHGTNCCNCCNTAYGTNGCNGCN ATGAAYCARCCNCARYTNTAYTCNGCNCCNTCNYTNTAYGCNTCNGCNCCNGCNYTNACN TCNGCNACNGGNGCNTCNACNTCNGCNACNGGNGCNAGYCAYGCNGTNGARGARACNGAY AARGCNAGYAARAARAARAARAARGARAARTCNGGNAARGARAARTCNYTNAAYGCNAAY TCNAGYATHATGATGAARAARAARMGNGTNTCNTCNATGGTNCARAARTGGCARCARGTN AARAARGARGTNGARAARGARAAYMGNGAYAARGARYTNMGNCARGCNGCNATHMGNGAR AARATHAAYCARYTNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARYTNGTNCAY MGNATHAARACNTAYMGNAARATHTCNCCNTGGACNTCNCAYTCNMGNGAYATHATGCAR ACNYTNTCNMGNTAYTAYAGYAAYGCNTTYTCNGAYYTNGARAARCARCARGCNTTYAAY YTNTTYYTNGGNGTNTAYATHCCNCARGARGGNGARCCNAAYYTNTGGGAYYTNCCNACN GAYTAYTAYYTNCAYAAYAARGCNTCNYTNGGNATGCCNATGTCNMGNCARAAYTAYTGY CARTGGTGGGAYGCNGAYGTNTGGGARACNYTNCCNYTNCCNMGNGAYGARGTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CCNCCNCCNTCNTCN ATGCCNAAYATGAGYACNGCNGTNCCNACNTCNCAYCCNGTNGGNGARCARGARACNCCN GTNTGGACNAAYAAYTCNCARCAYGCNAGYATHTGGTCNCARCCNTCNCARATGTGGAAY GTNGAYCAYATGAAYGAR---AARTCNCARGCNTAYAARATHCAYTTYGARAAYATGAAR MGNGARMGNGARGARGARAARYTNAARGARGARGARMGNATHAARCARGARYTNATGGAR AGYAARCARGARGARYTNMGNAARCARCARAAYGARYTNCARMGNCARMGNGARCARATG MGNMGNGARAARGARGARYTNGARAARGARMGNATHMGNAARYTNGARGARGTNMGNAAR GARGARCARMGNATHGCNCARYTNGARAAYGCNMGNCARAARAARGARCARATGGARCAR CARATGMGNTCNCARGARGARAARAARAARCAYGAR------------------------ ---------------GARGARAARAARAARMGNGAYCARGARAAYAARAARCARGARGAR AARMGNMGNAARGARGARGARAARATHAARGARCARAARMGNAARGARGARGCNMGNMGN GCNMGNGAR---------------YTNGARGARATHMGNMGNCARCARGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AGYCARMGN AARACNTGGGAYGCNCCNTCNGAYGTNAARYTNACNCCNMGNGGNACNYTNGAYACNGAY GCNATHGTNAGYAAYGTNCARMGNAARAAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GCNACNGARYTNTGY AAYAARGCNAAYGARGARTTYGTNGARGARAAYTAYCARAARGCNATHGAYYTNTAYTCN GARGCNYTNACNGTNGARGARACNMGNGAYGAYATHTAYTGYTTYMGNGCNCARGCNAAR YTNTCNYTNGGNAAYACNTCNGAYGCNATHAARGAYTAYGAYGARGCNATHMGNYTNAAY GCNGGNAAYCARAARGCNTAYATHAARAARGGNGCNYTNYTNYTNAARATGGGNGARGTN GTNCARGCNCARGAYGTNTTYAARGARGGNCARAARAAYTGYGGNAAY------------ ------------AARGAYTTYGARGAYTGGYTNGARAARGCNGARYTNMGNATGAARGAR YTNGGNATHGGNCARCCNGCN------AARACNGARAGYCARCCNCCNTCNATHAARCAY AAYTGGTAYCARACNCAYACNCAYGTNATHGTNACNGTNATGGTNAARAAYGTNAARAAR GARGARYTNACNATHGAYGTNGARGAYMGNTCNYTNCAYATHAGYATHAARMGNGAYGTN TCNAGY------GAYYTNAAYATGATHYTNGCNCAYMGNGTNGTNCCNGAYCARACNCAR TCNAARYTNTTYTCNACNAARATHGARGTNAARYTNAARAARTTYGARGGNATHCARTGG GCNAARYTNGARGGNTCNCCNGAYGCNGCNGAY---GCNAAYGTNATGCCNGCNTGYGCN GCNCCNGCNAAYGCNGARGCNCCNMGNTAYCCNAGYTCNTCNCAYCAYTCNMGNAAYTGG GAYAARYTNGCNGCNGARGTNACNGARGARGARAARAAYGARAARYTNGARGGNGAYGCN GCNYTNAAYCARTTYTTYCARAARATHTAYGCNGAYGCNTCNGAYGAYACNAARAARGCN ATGATGAARTCNTTYTCNGARTCNGGNGGNACNGTNYTNAGYACNAAYTGGGAYGARGTN GGNAGYAARAARGTNGAYGTNAARCCNCCNGAYGGNATGGARTAYAARAARTGGGAR--- ------------------------------------------------------------ ------GARGAYGCNAARAARCCNGARGARGCNCCNAARAARGCNAARTCN------GAY TCNGARAARMGNGGNMGNGGNMGNCCNCCNYTNTCNCCNGARGARAARGCNAARMGNGCN AARGCNGCNGCNCCNTCNTCNGGNMGNGGNMGNGGNMGNCCNAARGGNTCNACNAARGCN TCNAARAARAGYAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GTN YTNCARATHCARAARGTNCCNYTNTCNAAYGTNCARYTNGARGCNCAYGTNTAYTAYCAR CARAAYMGNYTNAARCARYTNTGYGARCARAAYAAYATHGTNGTNTCNGCNTAYGCNCCN YTNGGNGCNCCNGCNMGNCCNAGYCAYCAYCARAAYGARTTYGARTCNATHYTNGARGAY CCNGTNATHYTNCARATHTCNAARMGNCAYCARAARACNCCNGCNCARGTNYTNYTNAAY TTYYTNYTNMGNMGNGGNATGGTNGTNYTNCCNAARAGYTCNAARMGNGARMGNYTNCAR GARAAYYTNAAYTGYTCNGAYTGGTCNYTNACNGAYACNGAYTTYYTNGCNATGYTNAGY YTNGAYMGNGGNATHAARYTNTTYAARTTYYTNTAYATGAARGARCAYCCNGAYTTYTTY GARGGNGARGARTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNCCNATHAARTTYAGYYTNAAYMGNACNCCNTCNGCNACNAGYACNCCN CARACNAGYYTNCARAARTCNACNAARMGNMGNTTYGARGGNTTYATHCCNCCNGGNYTN CAYCARMGNTCNAGYGGNAGYGAYTAYGARGTNTCNYTNGAYAARATHGTNACNGARTAY YTNMGNAARCARCAYGCNYTNTGYCCNCARCCNATHTCNACNTGYCCNACNATGTCNYTN TTYYTNCCNCAYCARTGYCCNGARCCNYTNGGNMGNGAYTTYGCNTCNGTNTCNGTNACN ACNMGNYTNTTYGAYMGNCARATGMGNCCNCCNCAYGGNGGNCCNAAYGGNCARMGNYTN ACNMGNAARTAYYTNTAYTCNAARATHGCNYTNYTNTCNAGYGTNMGNGAYACNGCNAGY GAYGGNYTNGCNTGYTGYGCNTTYGAYTGYGGNGGNGAYACNATGTTYGTNGGNTCNTTY GCNGGNGARYTNMGNGCNATGCCNGTNAAYTCNGCNAAYGAYGAYTAYGTNGGNACNATH TGYCAYTCNTCNCCNYTNATHCARATHAAYACNTCNATGGTNGAYCCNAAYYTNATHATH ACNAGYACNTGGGGNGCNTCNCARAAYTGYGCNYTNTGGGGNTTYCARMGNGAYAGYGAY ACNTGYACNYTNAARTAYMGNTTYGAYGARCAYCAYGCNACNYTNGCNAAYYTNAGYCAY GAYMGNYTNATHGGNACNAARGARTTYGTNGCNACNATHTAYGAYACNACNACNGGNACN AARYTNCARMGNYTNTAYGAYGARAGYAARGCNAAYAAYTAYAARTTYAAYGTNGCNTCN TTYAAYACNACNGAYGAYYTNGTNYTNAAYGAYGGNAAYYTNTGGGAYGTNMGNTCNAAY AARYTNATHTAYAARTTYGAYAARTTYAAYCARTAYACNAGYGGNTGYTTYCAYCCNGGN GGNYTNGARGTNGTNATHAAYTCNGARATHTGGGAYATHMGNACNTTYMGNYTNYTNCAY ACNGTNCCNGCNYTNGAYCARTGYCARATHATGTTYAAYCAYGGNGGNGAYGTNATHTAY GCNGTNAARGTNGAYGAYGAYATGTCNGGNGARGCNTTYATGMGNMGNGAYTAYGCNTCN ACNYTNCAYACNTTYGAYGCNTAYAGYTAYAAYAAYATHGGNACNTTYGAYYTNAARACN AAYAGYATHYTNGAYYTNGCNGTNGAYMGNAAYGAYCARYTNATHGGNGTNATHGARAAY ATGGCNCARCAYGAYAGYGAYCCNGARGARTCNATHTGYMGNGTNTAYGARATGGGNAAR YTNMGNATGCCNGARGAYCARGCNGAYGARGARGARGAYAAYGGNCARAAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------MGNACNCCNTCNAARYTNCARCCNATHGCNCCNAARACNTCNCCN TGYTCNAARTCNGCNCCNTAYGTNCCNYTNCCNMGNATGAGYCCNAARMGNAARGARYTN AAYMGNCARGTNMGNCAYATHYTNCCNAARTCNTTYGTNTTYGARACNAARYTNGCNTCN CCNACNAARACNACNGCNYTNAAYYTNAARAARAARGCNGCNYTNYTNTGYCARAARATH CCNGTNAARATHYTNCCNMGNCCNGCNAAYGCNCCNGCN------ACNGAYMGNGAYGCN GARMGNAAYACNMGNATGYTNACNMGNTCNCARMGNGGN--------------------- ------------------ATHTCNAARCCNAARMGNAARGARGARCCNACNCAYAARGCN GTNAARMGNGTNAARAARATHGARGAR------GARTAYGARAGYCCNAARGARACNGAR AGYGARGCNAGYGARTTYGAYGARTCNGGNTCNCARGARGARGAYGAYGAYMGNACNAAR YTNGAYGAYYTNATGGCNGCNAGYACNACNATHMGNTCNGGNTCNMGNCARCCNACNTCN ACNGAYGAYGAYGTNAARACNAARGCNGARAARAARAARGCNATGTCNYTNGCNYTNYTN MGNCCNGAYYTNGTNCARAAYGAYCCNAARAARGAYGAYMGNGAYACNGCNTTYGCNCAR AARTAYTTYAAYGARGTNAARGARACNYTNTCNTCNGAYCCNGARMGNTTYTAYAARTTY YTNTCNYTNYTNAARGAYYTNAAYAARGAYCAYACNAGYCCNGTNGARYTNTAYYTNGAY ATGGTNACNYTNYTNTCNGAYCAYAARCARYTNGTNGARGAYTTYGCNGGNTTYYTNYTN TCNTTYCARGCNGTNGARTGYMGNTGYTTYTCNACNAAYGTNGARTAYTCNAARATHMGN CARTTYYTNMGNCARGTNGARGTNCAYTGYGGNCCNTCNATGACN---GCNTAYMGNMGN GTNYTNAARGCNATGTCNGCNTGGAGYACNATGTGYCARGARGGNACNYTNGARGGNAGY YTNMGNGAYAARYTNATGGGNYTNYTNAARAAYGTNCCNGGNGTNYTNGAYAAYYTNATH AGYTAYTTYYTNGAYGGNACNGTNCCNGARTGYGAYGCNATGGAYTTYGARGAYATHGAY YTNGARGARGARGARMGNGGNATGAAYAAYGARGAYGARTTYGARACNGTNGTNYTNCCN GAYGARCCNGARGAYTAYAAYACNAARACNTGYACNTGYCARTGYCAY---AGYAAYAAY GTNGAYGARMGNTAYCARMGNMGNAAYAARCAYTGYGTNTCNTGYAGYYTNCARATHTAY GARGGNCARCCNGTNYTNAARATGTCNMGNAAYGARTTYMGNCCNGTNTCNATHGTNTTY CCN---------TCNGARGARAARGARAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNGCNMGNAAYGAYYTNGARGARGTNMGNAAR YTNYTNGGNGAYAAYGTNAGYCCNGAYGTNACNAAYGARGAYGGNYTNACNGCNYTNCAY CARTGYTGYATHGAYGAYAAYGARGARATGYTNAARYTNYTNYTNGARTTYGGNGCNAAY GTNAAYGCNTGYGAYAGYGARATGTGGACNCCNYTNCAYGCNGCNGCNACNTGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGNCAYATG AGYTGYYTNGAYYTNACNGAYGARYTNGTNGCNGTNATHAARACNTAYCCNTGGCARTGY ATGGARTGYAARACNTGYGTNCARTGYATGGAYCCNTAYGAYGARGAYAARATGATGTTY TGYGAYMGNTGYGAYMGNGGNTAYCAYACNTTYTGYATHGGNYTNGAYGCNYTNCCNACN GGNCAYTGGGARTGYMGNAGYTGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATGGCNAARMGNGGNCCNCARTCNGARYTNAAYGAYMGNAAYTGGGAYGAYGAR GARGARGCNGARGARGCNGGNGTNTTYAARCARGCNTCNACNGAYACNYTNAARAARMGN GARATHAARAARGCNAARMGNMGNGGNGCNGGNGGNAARGCNGGNGCNTTYGGNGGNTTY GGNGGNTTYGGNGGNYTN---------ACNTCNAARACNGCNGCNCCNCCNAARACNTCN CARATGTTYGGNYTNGGNGGNMGNGAYTCNATHAARCCNYTNGAYAGYGGNTCNGCNGGN ACNTTYACNGGNGCNGCNGCNACNTCNCCNYTNGAYGCNGARACNGGNAARAAYGAYTCN TCNTAYYTNCAYTCNYTNAARGCNYTNAAYGARAGYGTNYTNGCNTGGATHAARCARCAY GTNGAYAARAAYCCNTAYATHATHYTNACNCCNATHTTYAARGAYTAYGARAARTAYGTN GCNAGYYTNGARGCNAARAARACNACNGCNGCNAAYGGNTCNTCNCAYTTYGTNGGNAAR GAYAGYGGNAGYGAYACNAARACNGCNACNGCNACNACNTTYTCNACNTTYGCNCARAAR AARTCNACNGAYGARYTNGAYGGNGAYGGNAARAARGAYAGYGAYAARGAYACNGARTCN AARTCNAARGCNCCNACNTTYTCNATHACNGCNACNACNAGYGTNAGYTCNGGNTTYGTN TTYGGNAARGCNGCNACNTCNTCNATHTCNTCNGGNTTYTCNTCN---------GAYTTY TCNTTYGGNCARAGYAAYTCNYTNACNGCNTCNTCNACNTCNTCNGCNACNACNACNACN GCNGCNGCNACNACNGGNTTYTCNTTYGGNGGNAGYGGNATGACNGCNGCNCCNTTYGGN ------------------GGNTCNGGNTTYTCNTTYGGNACNYTNGCNGCNAAYAARGTN GCNTCNGAYAARGCNCARGCNGGNAAY---TCNCARGARGGNGGNGAYGARGAYGARTAY GTNCCNCCNAARCCNGAYGTNAARGARATHAARGARGAYGGNTCNYTNTTYTCNAARMGN TGYAARYTNTTYCAYCARAARGAYGGNAAYTGGGTNGARMGNGGNGTNGGNAAYGTNCAY ATHAARCCNYTNGAYGARCCNAARACNCARYTNYTNATHMGNGCNGAYACNAAYYTNGGN AAYATHYTNYTNAAYATHAAYYTNACNTCNGCNYTNCCNACNTCNMGNCARGGNAARAAY AAYGTNYTNYTNGTNTGYGTNCCNAAYCCNCCNYTN------------AARGARGGNTCN ACNGAYCARACNCCNATHCCNATGYTNATHMGNGTNAARACNGCNGARGARGCNGAYGAR YTNYTNGCNAARYTNGARGARMGNAARGCNYTNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNCCNCAYMGNGTNMGNAAYGAYGGNYTNCARAAYTTYGAR AARGCNAAYAAYMGNGARGARATGACNGCNATHATGMGNGGNAGYCCNTCNGGNAGYGAR GTNMGNCCNMGNAGYGGNAARAARGTNATGGCNCAYYTNCARAARTCNGARYTNTGG--- ------------------------------------------------------------ ------ACNYTNYTNYTNAAYATHGCNAAYAARCCNGGNGCNATHGGNMGNYTNTCNCCN TTYATHGCNATHGAYCCNGAYCCNAARGCNYTNGTNAARTTYGAYTAYACNTCNGCNCAR CCNATHMGNGAYAARAAYGGNMGNTGYGTNAARGTNAARGTNGGNGARCCNGGNYTNTTY ATHAGYAARGTNCCNGARGCNATGATH--------------------------------- ---------------------------------------MGNATHGARGCNMGNAAYYTN CAYGAYGCNACNGTNGCNACNGCNAAYAGYTTYACNGARATHATHATHTCNTCNCARCAR GCNGARGTNYTNAARMGNGAYGAYMGNTTYYTNTAYATHTGGGGNACNGCNGGNACNGGN AARACNYTNYTNYTNTCNYTNAARGGNMGNTCNTGGYTNMGNAARAAYMGNGCNGTNGTN ATHYTNAAYACNMGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------YTNCARTCNGAYGCN MGNYTNGTNGTNACNGGNCAYAGYYTNGGNGCNGGNGTNGCNTCNATHYTNGCNGTNYTN YTNAARCCNTCNTAYCCNAAYYTNATGTGYTTYGCNTTYTCNCCNCCNGGNGGNYTNATG AGYCCNTCNGCNAGYAARTAYACNCARGAYTTYATHTGYTCNGTNGTNYTNGGNAARGAY YTNGTNCCNMGNYTNGGNATGTAYACNYTNYTNGAYYTNAARGTNAARATHYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR GCNATHAARMGNAAYGAYAARATHCCNTCNCCNTTYACNCCNATGGCNCCNTAYGAYGAR ATGAAYACNCCNGARYTNAARGAYGCNGTNGGNAARGTNGGNGTNAARCCNATGGGNAAR AARMGNATGMGNGARYTNYTNAARCAYATHTAYACNGARACNCAYCARTAYGARACNGAY TCNGAYGAYGCNAGYACNCCNGTNAARTGY------------------------------ ---------------CCNAAYCCNAARGCNCCNMGNMGNGARGCNYTNGCNTTYACNGAR GARTCNCARAAYMGNGTNACNGTNAARYTN------------------------------ ------------------------------------------------------------ ---------------------------------CCNGARAARAARAAYGTNGTNGGNTCN ACNGGNAAYACNACNTCNCARAARCCNTCNTCNTCNGCNTTYGARTCNGAYTGYATHGAY ------CARMGNAGYGGNGARGARGAYATHYTNAGYTCNCARGAYTCNAGYTTYAGYGAY GGNCCNGAYTTYCCNGARGARAGYATHYTNCARGTNYTNCCNGAYGAYGCN------GAY GCNCCNTGYACNCARYTNACNCARACNAGYATGGARGTNGTNAGYAAYMGNYTNATGGAY TTYYTNAARGAYAAYYTNAARATHTAYGARCARATHYTNATGTAYGARGCNYTNGARYTN GAYGTNTTYAARAARCARATHTCNGAYGCNGGNATHMGNGTNGGNTAYTCNMGNYTNCAR GAYTTYYTNGAYGARMGNTGYATHACNTTYTCNATGAARAAYATGAGYAAYMGNAAYAAY MGNCARAARCAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGNGCNGAYCAYCAYGAYAARCARMGNGARATHTTYACN GARAARYTNGCNGTNCARCAYCAYGARMGNAARYTNAAYATHMGNGTNYTNAARGCNTGG TAYGGNYTNATHCARAGYMGNTGGMGNGCNMGNACNGAYMGNAARAGYCARACNCARGCN AARGARGTNTGYYTNAGYYTNACNAAYGAYTAYGARGCNAARATHGCNATGYTNAAYGAR AARATHTCNTCNYTNGARAAYAARAGYTCNYTNYTNCARTCNGARMGNGARATGTAYTCN GARCARGTNAARAARGCNTTYATGMGNGGNATGTGYGCNYTNAAYATGGARACNATGTCN GTNTTYGGNGARGAR---------------------------AARGTNAARCARTAYAAY GGNYTNGAYGARTCNGCNMGNGAYATHCARGARGTNYTNACNTTYGAYGGNYTNTCN--- ------------------------------ATGGTNTCNACNACNGAYGAYGTNATHGAY CARTCNCARAAYTCNCARATHCCNTCNGAYTGYGTNACNTCNAAYAAYMGNCCNGTNAAR ACNGGNTCNCCNACNTCNMGNCARCCNCAYGTNACNTTYTCNTCNAARCCNATGAARGTN ACNAARACNAARCCNAARTCNGGNGGNAARGGNCARGTNAAYAAY--------------- AARGTNGTNTCNCCNTGYCARGTNYTNGTNCCNCCNATGGCNTCNGTNGTNGTNGARMGN CAYCCNCCNATHAAYAARCARACNATGGGNAARGCNACNGCNGTNMGNTAYCCNAARATG GGNMGNAARAARATHCARATHACNMGNATHAAYGAYGARMGNAAYMGNCARGTNACNTTY ACNAARMGNAARTTYGGNYTNATGAARAARGCNTAYGARYTNAGYGTNYTNTGYGAYTGY GARATHGCNYTNATHATHTTYACNAGYAAYAAYAARYTNTAYCARTAYGCNAGYTCNGAY ATGGAYAARGTNYTNYTNAARTAYACNGARTAYAAYGAYTCNGTNGTNAGYCARACNAAY AARGAYATHATGGAYATGYTNAAYAARAARGARAGYAARGGNGGNGAYTAYGAYGGNGAY GAYGAYGAYTTYCCNATHTCNCCNMGNACNGAYGARAGYTAYMGNAARATHGAYGCNGAR TTYGCNCARGCNATGAAYGCNGGNGGNYTNAARCCNTCNACNGTNCARTAYCARATHCCN GTNCARACNCCNGCNGCNCARTAYACNGCNGCNCCNGCNAGYATGGCNAGYGGNGGNTCN GTNATHGTNYTNCAR---------TCNGTNGCNAAYCCNGTNACNMGNCCNCARGGN--- ---GTNACNCARATHAGYGCNTCNCCNGCNCARAARGTNACNGTNAAYACNAAYGTNTCN AGYGGNGGNGCNCARGCNCAYCCNGTNGCNYTNCAYATGGCNGGNGARYTNCCNMGNGTN ATHGCNACNTCNGCNACNTCNTCNAGYCCNCARGCNACNGCNACN------AARAARCCN GGNYTNAARGTNGTNATHCCNGAYMGNGGNCCNGCNGTNGCNCARACNAARGTNCAR--- GGNACNGCNYTNGAYACNCCNAAYGTNTCNATHGCNACNCCNAAY---AGYCARAAYGCN CARGGNACNATHCARGCNATHYTNCARTCNGGNGAYYTNYTNAAYAGYGCNGAYATHGCN GGNYTNTCNCCNYTNGTNTAYCARYTNACNCAYCARGGNTCNGGNCCNGGNCCNYTNACN GCNGCNYTNCARGCNTCNGGNGTNTTYACNCCNGGNGGNTCNYTNTCNATGTCNACNACN CCNGTN---------ATHACNATGCCNGCNCARAARTCNGARYTNGTNAARCARGARCCN CCNGGNTCNCCNAGYMGNCARGAR------------GGNTCNTCNGTNACNCCNCCNCCN GCNACNACNCAYGGNGARCCNCCNGARAARMGNCARMGNTTYGAYACNGAYATGAGYTCN GAYACNTGYTTYAARTGYGGNGGNMGNGGNCAYTTYGCNMGNTAYTGYGGNGTNAGYGGN GGNCCNCARMGNGGNTTYCARGGNGGNTCNGGNGGN------------------GGNGGN TTYTCNGGNCARAARTGYTAYAARTGYAAYMGNACNGGNCAYTTYGCNMGNGARTGYACN CARGAYCARGARMGNTGYTAYAARTGYAAYGGNYTNGGNCAYATHGCNAARGAYTGYGAR AARCARATHTCN---ACNGGNGCNTGYTAYAAYTGYGGNAGYAGYGARCAYYTNCARMGN GAYTGYCCNGARGCNATHGTNAARTCNTGYTAYMGNTGYGGNGARTCNGGNCAYYTNGCN AARGARTGYCCNGCNGAYATHCCNGGNAARCCNTTYGCN------------GAYGAYMGN AARTGYTAYACNTGYGGNGGNGTNGGNCAYYTNGCNAARGAYTGYCCN------------ TCNCCNMGNAARGARTGYTAYMGNTGYAAYCARACNGGNCAYYTNCARAARGAYTGYCCN AAYGGNCCNCARGCNGAYGCNCARTGYTAYAAYTGYAAYGARGTNGGNCAYATHGCNMGN GAYTGYACNGCNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CCNGCNCCNGAYTAYGAYGARGAYGAYATHTCNCARYTN---CCNCCNCCNCCN CCNGARATHGAYGAYGAYYTNTAYCARGTNCCNCCNAAYAAYGCNCCNGCNATHYTNCCN CCNCCNCCNGARAGYATGTAYGAYATH------------------------------CCN CCNCARCCNTCNCCNGCNGGNGTNAAYACNTGYATHCCNGAYACNTAYGARGARAARGTN ATHGCNATHTAYGAYTAYCARAARYTNMGNGAYGAYGARYTNGARYTNACNGARGGNGAY GTNYTNTAYGTNATHAARAARAAYGAYGAYGGNTGGTAYGARGGNGTNAARGAYGGNATH CARGGNYTNTTYCCNGGNAAYTAYGTNACNCCNTAYATGAARMGNTAYYTNATHATHACN GCNGAYGAYTTYGGNTTYAGYAAYGARMGNAAYCARGGNATHATHGAYGTNTTYAARAAY GGNACNGTNACNAGYGCNTCNATHYTNYTNAAYTGYACNGGNACNGARGAYGCNGTNCAR YTNYTNAARCAYAAYAARYTNTGYTCNGGNYTNCAYYTNAAYYTNACNGARGGNCAYGCN ATHGGNAARAARGCNCAYTCNACNYTNACNAARTCNACNGGNGARTTYTGGGGNAARTTY CARYTNMGNAARYTNYTNCARGAYGGNAARATHAGYCCNGAYGARATHAARYTNGARATH GARTGYCARATHGARYTNTTYAARMGNAARATHGGNGARTAYCCNACNTAYGTNGAYGGN CAYCARCAYATHCAYGTNCAYCCNGAYGTNGCNCCNATHTTYTCNTCNACNYTNCARGCN TAYGGNATHMGNGCNACNMGNYTNCCNATHGARYTNTCNYTNAAYGAYAARGCNTGGATH AARCCNGCNGTNATHCCNTTYTAYAAYCARGTNATGGAYGAYGCNGCNAAYAGYGTNTCN AAYTTYAARAAYTGYGGNGTNMGNTAYACNGAYGCNTTYGTNGGNYTNTCNACNATGGGN GCNGAYATGACNGARGCNMGNYTNCARYTNAGYATHYTNGARGCNTTYGARGARAARGAR AARCARTTYTTYGARTCNTCNGARTCNTTYATHGCNTGYGARGTNATGTGYCAYCCNGGN TAYGCNACNGGNMGNGARTCNGGNGGNTTYGAYGGNYTNTCNGAYGAYTTYGGNTGYTCN AARGAYMGNGARCAYGARATHYTNGTNYTNAGYTCNCAYGARATGYTNGTNTTYTAYGAR AARAAYAAYATHGARYTNGTNTCNCAYCARTTYYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GAYCARGARYTNCAYGAYCARATHGCNGCNCARMGNGCNGARCARMGNTAYAARAAY CAYTAYGAYATGTGYGCNGARATGGTNGGNAGYATHGTNGAYTTYTCNTGYAARATHGCN GARTAYMGNGARYTNACNTCNAAYYTNYTNCCNGCNAARYTNATGMGNGARTGGAARYTN YTNTTYACNAGYGGNCARCCNYTNTTYGARCCNCARGAYGTNGTNAGYAAYGARYTNACN CCNGARCARGTNYTNGARGARGAYMGNCARCARYTNYTNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATHGTNGCNMGN MGNYTNMGNCCNTTYGCN---YTNGGNYTNTAYGCNMGNACNGGNAARTCNATHCAYACN ACNACNAARAARTCNGGNCARGCNYTNTAYMGNGARCAYATG------TTYGAYTAYAAR GARCCNAARTAYATHCARCAYACNGGNACNGCNTTYAGYGCNTTYATGTGGTAYTGGATH YTNTAYCAYTGYTAYTTYGARTTYGARCAYYTNGTN------------------------ ---------------------------------------------TTYYTNAAYAARYTN GGNGARATHCCNGTNYTNAGYGAYGGNTGGTTYGTNGCNGCNGAYTAYTAYTCNMGNGTN AARGAYTAYAAYGCNYTNATGMGNATGGCNYTNTCNATGGCNGARTCNGGNGTNAARGTN GCNGGNCARYTNTCNGCNCCNGTNGTNAAYMGNTAYCARCCNCARATHAAYAGYYTNAAY GAYATGGCNTGYAARACNYTNGAYAAYYTNGARACNAARTAYCCNGCNATHMGNCARCCN ACNGARCARTGGAAR---------GCNGAYTAYGTNGARCCNGTNGTNGGNMGNGTNAAR CCNGTNATHTCNCARGTNCARGGNATGGTNGAYGGNGGNAARCARAARATHAAYGGNYTN AARACNGCNGGNACNAAYATGGTNGARGGNGCNAARAAYMGNGGNGTNGGNACNATHACN CAYGTNTTYAAYACNACNTTYGARACNGCNCCNGGNMGNTTYGTNACNMGNACNGCNGAY GGNGCNYTNAAYATGGCNGAYAAYYTNGTNGAYAARTAYYTNCCNGGN------GARAAR GARCARGARGARGAYATGAAYGARGARYTNGARGCNAAR--------------------- ---TCNGGNTCNGARGTNGARAARATGGARGARATGGAYCCNACNCCNMGNMGNGTNYTN GTNCAYGCNGGNTCNGTNACNGAYAARATHMGNAARMGNATGTAYAGYMGNGCNATGAAR GAYATHACNTAYGCNMGNGCNMGNACNACNAAYGCNYTNAARMGNATGACNAGYACNGTN GARYTNATGGAYATGGCNAARMGNAAYYTNAAYTCNGCNAARGAYAARGCNGAYAAYATG TGGACNGARATHGTNAARGAYTCNGAYGTNTCNGARGARAAR------------ACNGTN TTYGTNGGNACNGTNGARGAYMGNATHGTNGCNYTNGGNMGNGTNGTNGCNMGNCARGTN AARTCNGGNGTNACNGCNTTYGARAARGCNTAYTCNGARYTNGGNGAYTTYAGYAARGAY CCNATHTCNAARTCNAARGARTAYAARGAYYTNATHTCNACNTTYYTNTCNGTNGAYTCN ATHAARAGYATHTCNTCNCARAGYYTNCARMGNGCNMGNGARTCNATGAARTAYATHCAR GAYMGNYTNMGNAAYYTNACNAAYTTYTCNACNAGYYTNACNTGGYTNGCNGTNGAYATH AAYATGGARAAYATHCCNATHAAYGARACNGAYYTN------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGTTYCAR AAYTTYAARCAYATHCARTCNGAYGAYGAYYTNMGNTCNAAYGARGCNYTNGARTAYCAY GCNACNATGGTNATGAAYACNYTNGAYGAYGCNATHACNCAYATHGAYAGYTAYGARTTY GTNMGNGAYYTNYTNTGYGARACNGGNGCNTCNCAYAARMGNTTYGARAAYTTYGARCCN ACNACNTTYYTNCAYATHAARCARCCNTTYYTNGAYGCNGTNAARGTNACNYTNGGNGAY MGNTAYACNGARAAYATGGARAAYATHTAYACNATHGCNATHAAYTTYYTNGTNGAYACN ATGGTNGARGGNYTNMGNGTNCARYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYTGGMGNGTNYTNCARATHYTNYTN CARCAYGGNGCNAARGTNAAYGARCCNGAYGGNTAYTAYMGNACNGCNYTNCAYTAYGCN GCNGARCARGAYCARAAYTGYGTNMGNATHYTNYTNGARAAYGGNGCNYTNGCNGAYCAR GGNGAYGGNTTYGGNGAYACNGCNYTNCAYTGGGCNGCNTAYAARAAYAAYACNYTNTGY GTNAARMGNYTNYTNGARMGNGGNGCNAAYGTNAAYGCNACNGAYTTYGAYTAYGAYACN CCNGTNAGYTGGGCNGCNMGNAARGGNAAYYTNGCNGTNATHCARGTNYTNYTNAAYTAY AAYGCNGAYGTNGAYATHMGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARACNGCNTTYGTN ACNGGNGGNGCNCARGGNYTNGGNCAYGCNTAYGTNGARMGNTTYYTNGARGARGGNGCN AAYGTNGTNTTYGGNGAYGTNAAYGCNGARGTNGGNAGYACNGCNGARCARAARYTNCAR GARAARTAYGGNAARGAYMGNGTNATGTTYGTNGCNTTYGAYGTNACNAAYGARGARAAR TTYAARGARGCNTTYGAYAARGCNGTNTCNCAYTTYGGNAAYATHGAYGTNTTYGTNAAY AAYGCNGGNATHYTNAAYGARGCNGTNTGGGARAARATGATHGAYATHAAYTTYACNTCN ACNGTNMGNGGNACNAARYTNGCNATGGCNCAYATGMGNAARGAYCARGGNGGNAARGGN GGNMGNATHATHAAYATHAGYTCNGTNGTNGGNYTNAAYGARCAYCCNTCNGCNCCNATH TAYTGYGGNACNAARCAYGCNGTNMGNTCNTTYACNACNTGYATGGCNAGYACNCCNGGN YTNGARGCNGGNYTNGGNATHGARATHGCNATHATHTGYCCNGAYCCNACNAAYACNGCN YTNATGACNGAYYTNGAYGAYGARAARATGCAYGGN------------TAYTCNAARGTN AARGAYGTNYTNCARGGNATGATHATHTCNCCNTCNYTNGTNGTNGAYGGNYTNTTYTCN YTNYTNACNMGNGAYGAYAGYATHAAYAARGCNATHYTNYTNGTNCARAARGAYGGNGCN AARTTYCARAARATGGARMGNGTNGAYYTNGGNAGYGARTGGCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TCN YTNATHYTNGGNYTNTAYATHGCNTAYGGNGTNYTNGCNGGNCAYCAYGTNTCNCCNYTN YTNCCNATGTCNACNGGNYTNAAYYTNACNCARTTYATGGAYMGNAARGTNGAYATGMGN MGNYTNGCNCCNMGNAARMGNCAYYTNAARYTNCAYMGNYTNATGMGNMGNATGGGNAAR GAYTTY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GTNACNAAYAAYAGY ACNAARACNMGNAARGGNTAYYTNAARAARTGYMGNGAYYTNGGNTTYCCNGCNGARGAR GAYGAYGTNYTNTGYACNGCNTTYGTNGCNGCNCARTAYYTNAARATGCARGAYTTYAAR GGNAARGTNTAYYTNGTNGGNMGNGARGAYAGYYTNGGNAARGARYTNAARGAYGCNGGN ATHTCNTAYATHGGNGCNGGNCCNGAYGARGCNCAYTCNATHGARCARACNGAYYTNATH GAYACNAARYTNGAYCCNGARGTNAAYTGYGTNYTNGTNGGNTTYGAYCCNTAYATHAGY TAYCCNAARTGYYTNAARGCNAGYAGYTAYYTNAARAAYCCNGAYTGYYTNTTYATHGGN ACNAAYGARGAYCCNTGYYTNCCNACNAAYGGNCCNATHAARYTNCCNGGNACNGGNACN ATGGTNGCNTTYGTNAARGCNGGNGCNGARMGNGARCCNATHATHGTNGGNAARCCNGAR GTNGGNATGTTYGARATHYTNCARAARYTNCAYAARYTNGAYCCNTCNMGNTGYYTNATG ACNGGNGAYMGNYTNGARTCNGAYATHGCNTTYTCNAARMGNTGYGGNATGAARTCNYTN YTNGTNYTNACNGGNAAYGAYTGYGTNGAYGAYATHGARAARMGNGGNATH------ACN CCNGAYTTYTAYGCNGARMGNYTNGGNACNYTN------ATGAAYMGNAAYMGNCARMGN GAYGGNMGNGGNATGMGNGAYAAYMGNGGNAGYMGNGGNGGNGAYGGNYTNYTNGGNGAR GGNCCNCCNGCNGGNGGNCCNGGNCCNATGATGAGYGGNAAYCCNYTNGGNYTNMGNGAY ACNCARYTNGCNYTNGCNCARTCNYTNYTNCARCARCARCARYTN---ATGAGYTCNGGN TTYGGNGGNGCNGGNAGYGAYTTYGGNGGNYTNGGNGCNYTNGCNGGNGGN--------- ATGCAYTTYYTNCARCARCARCARCARCARATGMGNATGCCNYTNGGNGGNGTNGGNGGN ATHGGNGGNYTNGGNGGNATGMGNAAYGAYMGNAARMGNAGYGGNGGNCARYTNMGNMGN GAYAAYGAYGARAARMGNGGNMGNMGNGAYTCNTGGGGNMGNGGNGARMGNGAYMGNTCN ---CAYGGNAAYAGYAAYMGNAGYGGNCARGAYMGNGAYMGNAAYMGNMGNGARTCN--- GAYAARGARMGNAAR---AARCAR---GGNGARGAYTAYGAYCCNGCNGARCCNACNGAR GAYGAYGAR------GAYAGYAARGAYAARGAYGGNTCNAAYYTNTAYTGYCAYGTNTGY TCNGTNTCNGTNTAYGAYGARGARAGYTTYCARMGNCAYYTNAAYGGNGTNAARCAYAAR GCNMGNATGGARAGYATHGCNTCNGTNCAYAAYGTNMGNTCNTCNCARATGAAYTTYMGN YTNAARGCNGARGARCAYYTNMGNAAYATHGARMGNAARGGNGGNMGNGAYCCNGAYTAY TTYTGYAARATHTGYAAYAAYGAYYTNGCNATHCCNTGGGARAARCAYMGNTAYTCNAAY ATHCAYAARCARMGNYTNYTNCARGTNMGNAARGGNTGYGGNTGGTGYAARGTNCAYGAY TTYACNAAYTTYACNGARGTNYTNGARCAYMGNGARACNGARGARCAYAARAARAAYGCN GARCARTAYGGNAARAARGARGARGARAARGAYGAYTCNMGNCARMGNATHAARGAYGGN AARGARMGNAGYAARCCNTCNGAYAARAARGAYAARATGGARGARGARGAR--------- ------------------------GARGARGARGAYYTNACNATHCCNGARTTYAAYGCN GARAAYCCNGTNGGNATGGAYTAYGTNATHCCNGTNACNGGNTAYTTYTGYAARYTNTGY CAYAARTTYTAYAAYAARAARTCNGCNMGNGCNACNCAYTGYCARAGYGARATGCAYTAY GARAARTTYAARGARGCNACNGARGTNAARATHGCNGCNMGNGARAARMGNAARGARGAR GARMGNATHMGNAARGARAARGARGCNGARGARGARGCNATGGARGARGAYGGNGARGCN GTNAARCARGARGAYGAYGAY------------------------GARATHAARAARGAR GAYGGNGAYGARCARAAYGARGAYGARAAYGAYGAYGGNGARGARGAYGGNGAYATHGAR GAYGAYGTNATGYTNGCNGARGGNGAYGAYGTNGGNGGNGAYGARGAYCCNATHGAYAAY GAYCARGAYYTNTCNGGNAGYATH------------GGNGGNGARAAYGARTCNACNYTN GTNGGNGGNACNGTNGARAGYTCNAGYTTYATGTAYGTNCCNGGNGAYGTNGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARAARATHAAYAARATGGGNGTNGAYMGNGCNGARACNGCNYTN YTNTGYGCNATHAGYATGACNAGYATHGAYTGYCCNGGNYTNGTNAARCCNGCNACNGTN TCNGARGTNCARACNGTNYTNGTNGARTCNYTNGARGCNTAYTCNGCNAARGGNCAYTCN GGNGGNMGNYTNCARATHYTNYTNAGYYTNATGCCNCARGTNMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TCNTCNTCNAAYCAYCCNATHGTNYTNAARCCNTAYTAYYTNTCNGTN GTNGAYGGNTAYTCNCARCCNTCNCAYAARGCNYTNGAYGAYGGNCAYATHGCNAGYYTN ATHAARGAYTAYGARGCNACNGARGGNAARCARATHAARGAYATHATHAAYGAYCARAGY CARGCNAARGTNAARGGNGGNTCNGARGGNTAYGARAARTCNAAYGTNAARCAYGGNGAY AARGTNTTYCAYAARTTYTGGAARGARATHCARAARTTYCCNGARCARTGYATHMGNTAY GAYMGNGGNGGNCARCCNYTNYTNGTNCARAGYYTNAGYCCNATHCARTCNGTNATHCCN CCNTGYGCNCAYTGYGGNTCNAGYMGNGTNTTYGARTTYCARYTNGTNCCNGCNYTNATH CCNTGGYTNTGYTCNMGNGARGGNAAYCARTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN AAYATHATGGGNGGNTAYYTNTAYYTNGARAGYYTNCAYCCNGTNAAY------------ GARCARGAYAARATHGTNMGNATHCCNCARAARGTNCARGARMGNTAYYTNTCNGTNGTN AARGARTTYATHGARCARGGNTTYYTNGAYTTYATHCAYGGNYTNAARYTNGCNGTNATG AARGARTTYGGNMGNATHTCNYTNAARGARCARYTNGGNYTNGAYAAYYTNGCNTCNATH TTYGGNCAYGTNMGNGARMGNATHGARTGYGGNGTNGAYAARCCNACNATHTCNYTNTAY CCNTAYYTNATHAARTGYGARCARGTNGCNGTNCCNGAYTCNCARAGYGTNATHAGYCCN GAYGAYGARYTNTAYGAYAARYTNATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TTYTTYATGTCNTGYGCNATHMGNATGGAYAARYTNCCNGTNAARATGCARTCNTAYYTN CARYTNCARATHTCNCARYTNTTYTTYAAYGCNGARAAYCCNGAYGTNCCNCCNATHCCN ATHATGCCNYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GCNTCNTGYATG AGYGTNGAYAAYCCNGTNTTYMGNTCNTTYATHGGNTAYGCNGCNGTNGTNYTNYTNAAR ATGATGYTNATGAGYACNATHACNGCNTTYTAYMGNATHACNAARAARGTNTTYGCNTCN GARGARGAYGCNGARTAYTTY---------AARGTNAARAARGGNATGACNYTN---AAY GAYCCNGAYGTNGARMGNGTNMGNMGNGCNCAYCARAAYGAYYTNGARAAYATHYTNGCN TTYGTNYTNYTNGGNGCNATHTAYTCNACNACNGGNCCNGCNATGTCNACNGCNYTNYTN CAYTTYMGNATHTTYACNGCNGCNMGNATHYTNCAYACNYTNGTNTAYYTNACNAARGTN CCNCARCCNGCNMGNGCNATHACNTTYTTYATHAGYTTYGGNGTNAAYATGTCNYTNGTN TAYAAYATHATHYTNCARGCNGCNTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNGTN CARATHTGYATHGAYAAYACNMGNGGNATHYTNTAYGCNMGNACNCARAAYGGNTCNATH CARGTNTTYGAYYTNGGNGARAAYAARAARGGNYTNAGYAARGTNGCNTAYCARTCNCAR GCNTCNATHYTNAAYTCNGCNTCNGCNTTYGCNMGNACNATHGARAARTCNAAYTTYAAR TCNATHATGCAYATHTCNGCNATHACNCAYMGNGARGCNGARAGYGTNCAYYTNGTNGCN ATHACNGARACNGGNGTNMGNYTNTAYTTYTCNACNGTNCCNTCNAARCARYTNGAYTAY MGNCCNTGYACNYTNAGYYTNATHCAYGTNMGNYTNCCNCCNGGNTTYTCNGCNACNTCN ACNCCNGARMGNCCNACNAGYGTNCAYACNGCNTTYTAYAARAARGAYACNYTNATGYTN GTNTCNTCNCARAGYCARGAYMGNGAYACNYTNTGGTGYATHGGNCCNGAYTCNTTYCCN TTYCARAARCARYTNATGGARGCNCAYACNATHATHTCNTGYGGNGGNAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CARAGYTAYATHAARGARGGNGTNACNAARACN TGYGGNTGYMGNATHAARACNCARGGNAAYCCNTCNGGNGTNCCNGTNTGGCARTAYTCN TAYAAYCARGTNGGNGGNGCNGTNACNAAYGGNYTNACNGTNAARTAYGAYTCNAAYGAY CARTAYCCNTCNTAYACNTGYATHGGNGTNTCNMGNYTNGGNTAYGGNGCNGCNACNGTN TAYMGNCCNTTYGCNTAYGGNCCNACNMGNATHTCNCARTCNTTYATHGAYAARCARACN GAYACNATHAAYAARTGY---GAYGARACNACNTCNTTYACNGTNTAYTGYGAYATHGCN ATGAAYAAYCCNACNGTNGTNGTNACNTCNAGYCARGGNGAYACNATHACNCCNCARGTN GARAGYACNYTNCCNYTNTAYTAYMGNCAYAARTAYAARGTNGTNCCNACNMGNGGNGGN ATHGAYACNATHACNTGYCARGCNACNAAYACNAARTTYTCNGAYYTNACNACN---ACN AGYAARACNATHACNGTNCARGARCCNCCNCCNTCNAARCCNGTNATGGCNATHGTNATH TCNAAYAARGARCAYGCNGTNGGNAAYGGNGTNGTNACNATGACNAAYGGNGAYACNGTN AARGTNAARTGYMGNGTNAAYGGNGGNTAYCCNMGNGTN---AGYAARGTNACNACNACN TGYACNGGNAARAAYGTNAAYAAYGARGCNGARGCNATGCARACNYTNTAYGTNGARAAY AAYGARGARAARTGYTCNTGYGARGCNGARCAYGTNACNGGNTGYTAYGGNAARGARTCN GTNAARGAYTTYCAYGTNCCNATHACNYTNGCNAARGGNMGNGARAARGTNMGNGARATG TTYYTNAARAAYAARCAYATHACNGAYYTNMGNGTNATHGAYATGYTNGTNATHAARGGN CARATGGARYTNGTNGARACNGCNAAYATHTGGAARCARAARCAYCAYATHATGGCNTAY TTYAARGAYACNGTNAAYCCNAARCCNACNGAYTTYYTNAGYAARTTYTAYGARGGNCAR GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARTTYCCN YTNCCNCCNTGYMGNATHTGYAARGCNCCNGGNGCNGGNTTYCAYTAYGGNGTNAAYACN TGYGARGCNTGYAARGGNTTYTTYCAYMGNAGYYTNAGYCAYTGGCCNMGNTAYAARTGY YTNAAYAARGGNAARTGYACNATHCARCARGGNCARGGNAARATGTGYMGNYTNTGYMGN TAYCARAARTGYYTNGAYACNGGNATGTCNAARTCNGCNATHAARACNGGNMGNTAYAAY TAYAARAARAARACNGAYGAYATHYTNGARGTNAAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNATHCCNGTNGCNAAYTCN---TTYGCNYTNYTNAARCCN GARGARGARYTNGARGARGARMGNMGNGCNMGNMGNAARYTNGARCARCARCARAAYAAY GARGCNTCNGCNAARAARAARGAYGAYAARAARAARAARGCNAGYGARAARGARMGNYTN CARCARYTNGCNTTYGGNTTYTCNMGNGCNTCNGCNGGNAARAARAARTCNGGNAARAAY AARAAYTCNAAYGCNAARGARCAR------GAYTGGCARCARTGGAARGARCAYGAYAAR GARGTNGTNGARGAYCARTTYMGNGAYGAYYTNGARAARGCNATHYTNGARAGYCARGTN CARYTNGARCARAARAARAARGAY------GAYMGNCARGARMGNYTNAAYGGNGGNCAY GARGCNTCNGCNACNGARGCNGARGGNAARAARAARAARAARAARGAYAARGCNAARACN ATGTCNYTNGARGARTTYAAYAAYYTNCARAARCCNAARTCNCARAARGCNTCNGARGAY CAYCARGAYGAY------------GTNTCNMGNCCNCCNATHCAYCAYMGNGTNCCN--- TCNGARAARGAYTCNAARTTYTTYAAYAGYGCNCARCAYGARGCNAARCARATHATHAAR AARGAYAARATGCARGARGARTAYMGNAARACNTGYGCNGCNGAYAAYGCNGTNGTNGCN AARYTNAARAAYGAYATHGARATHMGNGAYAARACNATHAARGAYYTNAARCARAARATG GARAARATGGARAAYGARACNAARCARGTNAARCAYMGNAAYAARCARYTNTGYGTNATH YTNGCNCARGGNGARATGAARGAYAARGCNCARGTNYTNYTNCARGTNGAYGARYTNAAY AAYGTNAARGAYGARYTNATGGARCARGTNACNTCNYTNACNGCNGARYTNGARAARGAR AARTCNAARAAYMGNGCNYTNAARCCNGARGGNGAYAARCCNAARTCNGGNAARCARGGN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MGNACNGCNAGY GCNTCNAGYYTNTAYTGGAGYTGYGGNTAYTGYGAYTTYCARAGYAGYAGYCARGCNGAR ATHAARGARCAYTCNAAYMGNACNCAYCCNGGNAARCCNCAYMGNTAYGTNGCNYTNATH AARAAYATGACNCCNGAYTCNATHATHAAY---AARAAYGCNAAYAARTAYAAYTCNAAY CCNTCNCCNTCNYTNMGNAARGTNGCNCCNGCNGTNAARTCNTCNCCNTCNTTYTCNTCN GTNAARYTNGAYAAYGTNGCNAAYMGNTTYGAYTCNGAYMGNGAYATHGTNAAYYTNTCN AAYAAYGCNGAYGAYAGYACNYTNAARGTNAARATHGGNACNCCNMGNGGNCCNMGNMGN GAYAAYACNACNTAYAARTGYTAYCAYTGYACNTAYACNGCNAARMGNCAYTCNTCNATG AARTCNCAYATHTAYTAYAARCAYMGNGGNAARGGNYTNYTNGCNGTNGAYGARGAYATH ACNACNGGNGGNCARGTNTTYTTYTGYGCNMGNGAYGAYTGYACNTTYAARTCNATHAGY CCNACNTCNTAYYTNAAYCAYGTNGARCARTGYACNCCNTGGCAYAARCCNGARYTNGCN GAYGTNGARGTNGARCCNCAYATHMGNGARTGYNNNCARCARACNGTNACNTTYGCNGAR ATGGCNYTNGAYAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TTYGTNTTYGAYTGYCCNYTNTTYAARAARTCNATH YTNATHGARGTNAARGARMGNGTNATHCAYTCNGAYGAYGCNTTYGCNCCNGTNGGNTAY YTNAAYYTNMGNAARTGYTGYYTNCARGARAARCCNGGNCAYGAYGTNTCNAGYTTYGTN AARACNATHAAYGARMGNGCNATHTCNACNACNTCNAARTGGYTNGCNAARCARYTNGCN AAYAGYGAYAAYGAYMGNGARTAYGARAGYTCNGARACNGARAARAAYGAYGAYGGNCAY GCNCARGCNATHCARCAYTCNYTNGARGARGGNGAYATHGCNCAYGCNAGYGAYGGNAAY AAYTTYCARGTNTCNGGNATHMGNGCNACNACNTGYTCNACNTCNGAYGTNTCNCARGCN GCNACNATHGCNATGGAYTCNYTNAARGARTGYATHACNAARATGGGNCAYGARATHTCN GAYGTNACNTCNYTNTCNYTNTAYGTNGGNAGYATGTCNAAYTAYATHGCNATHAAYGCN GTNTAYAARAARTAYTTYGARATHAAYCCNCCNACNMGNATHTGYATHCARGTNTGYYTN CCNCCNTCNGTNGTNTTYCARYTNGAYTGYGARGGNTGYAARACNATHGARGAYGAYMGN MGNACNATGTAYGTNCARAGYYTNTCNYTNTGGGCNCCNGCNAAYYTNGGNCCNTTYAGY CARTCNATHTCNYTNAAYGARAARATHTAYGCNTCNGGNACNACNGCNYTNATHCCNTCN ACNYTNAARYTNATHGAYGGNGGNATHMGNGTNCARAGYMGNGTNTCNTTYCAYCAYYTN YTNGARAARTTYTAYGGNYTNTGGCCNCAYTAYYTNYTNGGNAAYTCNCCNYTNATHAAY TGYTAYGTNACNAARMGNGARCAYATHTGGGCNGCNMGNMGNGARTTYGARYTNATHYTN CARGAR------------ATHACNTCNGGNGGNYTNAGYCCNAARGTNAARTAYTGYGTN GTNCCNMGNYTNCCNCARGGNGCNYTNGTNGARTGGCARGCNTAYGCNTGGATGTTYGCN ------------GAYTCNGARGARGARGCNACNCARTCNACNAARAAYTTYCAYAAYTGG ACNATGGARATGGAYTGYGTNMGNTTYCARCARCAYATHTGYTGYGCNATHAARGTNGAY GTNCARGARYTN------------GCNMGNAAYGTNYTNGCNTCNTAYACNGARGCNYTN GGNAARYTNAGYGGNCARGGNACNGCNAARMGN---------YTNGCNAARATHTAYTAY YTNGCNGAYAARTTYTCNTAYAARGAYYTNGTNCARAGYTTYTCNCARGCNYTNCCNCCN ---GARGAYMGNGTNATGYTNCCNACNYTNTCNTTYGTNCCNGTNATHGGNYTNGAYACN GARMGNCAYYTNYTNACNTGGTGYCAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CCNYTNACNTGGATHACNCAYGAYAAYAARMGNYTNTCN TTYGTNMGNAAYGAYYTNACNTAYACNAARGGNMGNATHGTNGTNCARACNACNGGNGTN TAYCAYYTNTAYAGYCAYATGACNTTYTCNTCNGTNGGNAAYGCNAAYGTNGAYAARATG CAYGTNTTYCAYTCNATHTCNAARMGNAARGARYTNATGGARACNYTNYTNATHACNMGN GTNAGYYTNGGNGARGAYGAYYTNAARTCNACNAAYYTNGARGGNTCNTTYGARYTNAAR GAYGGNGAYGARYTNGCNGTNTAYTTYAGYCAYCCNTCNYTNYTNACNGGNGARYTNCCN GCNAAYGTNTTYGGNYTNTTY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GGNATHCCNAAYCAYYTNYTNACNGARATHAARAAYAARYTNAARTGGYTNMGN TCNGARTTYMGNGARMGNYTNGTNMGNGARMGNMGNYTNMGNAGYGARTTYMGNACNGCN YTNTCNTCNTCNGARGCNGAYMGNCARTTYYTNATHGGNCARYTNGCNMGNAARGAYGAR GARYTNGAYGAYYTNGCNYTNGARAARCARGARATHGCNTAYAARGARATHCARTCNTCN AGYTTYGTNGARGARYTNGARGARCARGTNYTNGAYYTNTCNGAYGARYTNCARYTNMGN AARATHMGNGARGAYGARCARMGNAARATGTTYGTNMGNGARAARCAYAAYATHATHGTN GARATGGARGAYATHATGGAYGCNGARAARGARAARGCNAARATHGARGAYMGNTAYMGN MGNYTNCARGARACNYTNAARTCNYTNCAYCAYGAYYTNAAY---ACNAARGTNGARAAR GGNAARAARACNAAYGGNATHYTNMGNTCNCCNTCNCCNAAYGGNACNCCNAARAARMGN AAYCAYGTNMGNATHTCNTCNACNACNCCNACNAARGARTTYGAYGCNGAYGARCCNATH YTNGGNACNCCNTGYCAYACNCCNCCNCCNATGGCNYTNACNGAYGAYGARTTYMGNTCN AARTTYYTNCCNCARACNCCNCARGAYATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARACNTCNCARAAYGAYMGNCAYATHCARATHYTNAAR CARCARAAYGAYGARYTNCARGCNCARATHAARGCNYTNCARAARTCNCARGTNAGYGGN AARGCNYTNATGAAYTCNAAYTTYYTNGAYGAYMGNGARGAYGAYGAYTAYGARAGYTAY GARGAYGARCCNGTNGTNGCNTCNCCNCCNAARMGNAARAARACNAARACNAGYCAYAGY ------------------------------------------------------------ ---------------------YTNAARTCNCCNTCNTCNGGNYTNMGNYTNGGNYTNTCN MGNAAYCARMGNGTNAARCCNYTNCAYGGNTCNTTYATGGTNGTNGGNYTNGGNAAYTTY CCNTAYCCNGAYACNMGNCAYAGYGTNGGNATGAARGCNYTNGAYGAYTTYTCNAAYAAR YTNGGNYTNAGYTGGGARAAYGTNCARGGNGGNCARGGNGGNYTNYTNTGYAARACNACN ACNCCNGGNGAYAGYCARGARYTNACNCARATHTAYYTNTTYAARCCNAARTCNYTNATG AAYATHTGYGGNAARAAYGTNGCNAARGTNGCNAARTCNYTNGGNYTNATGTCNGAYTGY ATHTAYYTNGTNCAYGAYGARYTNGAYYTNCCNYTNGGNAARGTNTCNATHAARAAYGGN GGNAGYGCNAAYGGNCAYMGNGGNGTNYTNTCNTGYATHGTNAAYYTNAARTCN------ ---------------TCNGGN---------------------------------YTNCCN MGNAARTCNACNGCNATH------------------------------------------ ------------------------------------------------------------ ------------------------------CCNCCNAAYAARCARYTNMGNATGCARAAR MGNATHCCNYTNYTNAARGARMGNCAYCCNCCNATHTTYCARTCNCCNCCNMGNAARGTN ACNTCNACNGTNACNCCNCARTCNCCNCCNCCNGCNCCNMGNGTNGARACNTCNYTNGAY ATHAARGCNACNYTNAARGAYAARGAYYTNAARGAYGTNYTNGGNGARCARGCNCCNAGY GTNAARAAYCARTCNGTNGARAARCCNGTNGCNGTNGARAARGTNGGNGTNTCNGTNATG AAYGARTCNGTNCARACNAAYATGAARAARGGNGTNGCNCAYGCNGCNCCNGARGCNCCN GCNGARTAYGCNYTNAARTAYAARGCNGGNGTNGCNCCNCCNMGNGCNATHAARAARTTY TCNGARTAYCARAARCARTTYCARTGGAARAAYGGNAARAARGCNTCNCCNYTNYTNGCN GCNGARCARATHGTNTAYACNAGYAAYACNGARYTNGGNCCNTAYAARACNGARGCNATH CCNAARGTNTCNGARTAYAARMGNGARTTYCARMGNTGGAARCCNACNGARGTNAGYAGY TGYYTNAAYYTNAAYGARAAYAAYAAYATHAAYAAYCARGGNGGNAARAGYAARACNGTN GTNAARMGNAGYAARAGYGCNGCNGCNGAYYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYMGNTAYTTYGCNTAY GGNAGYAAYYTNYTNGARGARMGNATHCAYATHAARAAYTCNACNGCNMGNTAYGTNACN AAYGGNACNYTNAARAGYTAYMGNYTNGGNTTYGARAARCCNYTNACNTCNGAYGARGAY ---ATGGAYGCNGTNGCNACNGTNMGNCCNGGNGAYAAYGAYGARGTNAARGGNTGYGTN TGGGARATHGAYYTNGAYCARATGGAYAAYYTNGAYGGNCARGARAGYGCNTAYAARGCN ATHCARGTNGAYGTNYTNYTNGAYAAYGGNTCNTCNTGYGCNTGYMGNACNTAYGARATG AAYTGYGGNGTNTTYCCNGAYGARACNAARCCNCAYCCNTTYTAYCARMGNATHTGYGTN GCNGGNGCNAARCARCAYGGNYTNCCNGAYGARTAYGTNMGNTTYYTNGARAGYTTYGAR CCNACNAGYCARYTNAARGCNCCNACNGTNTAYGARGTNYTNGCNCCNGTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATHACNYTNACNATHGGNCARGCNTTYGARYTNGCNTAY AARMGNTTYATHGARTCNTCNACNCARGAYYTNGAYYTNAARAARCARTTYYTNYTNYTN CARAARAARGTNAGYACNYTNCARTTYGARAAYGAYGCNYTNAARAARMGNYTNGCNGAY YTNGARMGNYTNAARGAYMGNTCNGAYGTNGARCARTAYAARACNAAYAAYCARCCNACN AAYCARACNTCNGTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CARCCNTCNCCNTCNGCNMGNGGNGTNAARMGN TCNCAYGARGARGTNGARAAYATHAGYGAYTGYTCNAAYTCNCCNAARCCNTCNCCNCAR AARAAYAARAARMGNTGYTTYACNTGYAGYTGYMGNYTNGARYTNGCNCARMGNACNATH GGNAARTGYMGNTGYGAYCAYGTNTTYTGYCCNATGCAYMGNYTNCCNGARYTNCAYGAY TGYGARTTYAAYCAYAARGARGAYGGNMGNMGNGARGCNMGNGARAARATGGTNAARCCN ACNMGNCAYATGGGNACNTCNTTYMGNMGNGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TCNGGNCARCAYAARAAR AARATHTTYATHAAYGTNACNYTNGARGGNYTNAARGTNATHGAYGCNATHTCNYTNGTN GTNYTNCAYACNCAYCCNGTNCAYMGNATHTCNTTYATHTCNMGNGAYACNACNGAYAAY MGNGCNTTYGGNTAYATHGTNGGNAAYGGNGAYGGNAAYCAYACNTTYTTYGCNATHAAR ACNGCNGCNGCNGCNGARCARYTNGTNYTNACNYTNMGNGAYYTNTTYCARGTNGTNTAY GARYTNAARAARAARCARGTNGAYGARGCNAARGARAARYTNGARGGN------AAYGAY AARGARTCNGGNACNGARAAYGARAARCCNTCNGGNCARGGNTCNACNTCNGARGARGGN CARACNCARAARACNGCNCARGCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GARGTNATHCCNAAYTGGGAYGCNAGY AARAAYACNAARAARGTNAARGARYTNTGGTGGTCNGGNATHCCNCCNAGYGTNMGNGGN ---------------ATGTCNGGNATHACNTGYYTNACNTGYAAYGTNGGNTTYGARGAY GTNGAYYTNGGNMGNATHCAYTAYAARACNGAYTGGCAYMGNTAYAAYYTNAARMGNAAR GTNGCNAGYYTNCCNCCNGTNACNYTNCARAARTTYGARGARMGN---------CARMGN GCNCARGARCARYTNGAYTCNACNACNAARCARGARMGNTGYGCNTGYAARCCNTGYAAY AARTGGTTYAAYACNACNAAYGCNTTYGARAAYCAYYTNCARTCNAARAARCAYAARGAY GTNATHTCNGGNGCNGCNAARGTNAARAARNNNAARMGNAARAARGCNYTNCCNAARCCN TCNACNGCNTCNCARGTNYTNAARAAYAARCAYTCNAAYGARGARGARTAYATGTCNGAR GAYGARGAYGAYTGYGAYGCNGARTCNTGGGAYAGYTAYGAYGARAARATHATHGCNYTN GARGARTGYYTNTTYTGYTCNYTNGTNAGYCCNTCNATGGARGAYAAYYTNACNCAYATG ACNTCNAGYCAYGGNTTYTTYYTNCCNGAYGCNGARTAYATHTGYGAYYTNGARGGNYTN ATGTCNTAYYTNGGNGARAARGTNGGNGCNGGNTGYGTNTGYYTNTGGTGYAAYGARAAR GGNAARMGNTTYMGNGAYTCNAARGAYGTNCARAARCAYATGATHGAYAARGGNCAYTGY AARATHTTYCAYGARCARGARACNYTNTAYGARTTYACNGAYTTYTAYGAYTAYTCNAAR AGYTAYCCNACNGTNGARGGNGARGAYCCNGAYACNCAR---TCN---GARACNGTNGAY ATHYTNGARYTNGAYGGNGAYGGNTAYTCNYTNACNYTNCCNTCNGGNACNGTNATHGGN CAYMGNTCNYTNGTNMGNTAYTAYMGNCARAAYYTNGCNCCNTAYMGNCAYGARAARACN AARACNGTNYTNCCNAARATGYTNGCNCAYTAYAARGCNYTNGGNTGGACNGGNGCNACN GGNCCNYTNGTNGARMGNMGNGCNAARGAYYTNCARTAYATGCARMGNGTNMGNAAYMGN CAYTTYATGAARYTNGGNACNCARGGNAAYAAYYTNMGNYTNMGNYTNMGNYTNCARAAY ------------------------------------------------------------ GTNTCNTCNCAYAAYAARGARATHYTNYTNAGYTGYYTNTTYATGGARGGNGTNGGNAAR TTYGCNYTNGTNYTNGGNCCNGARTTYGGNGTNCAYYTNATHAAYACNYTNTAYCCNYTN GTNGARAAYYTNGGNCAYAARAAYACNCAYATHAGYAGYACNGCNTTYGAYACNYTNACN CARATHTGYGCNGCNTGYGGNTAYACNTCNYTNGAYAAYYTNATH--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TCNCCNAGYTTY ATHGAYTCNACNGGNAARGCNACNATGACNACNTGYGTNGCNAAYAARGCNACNATHGTN ACNGTNGGNATHGTNAGYMGNCCNGCNAAYYTNGGNGGNTCNGARYTNACNCAYAGYTCN CCNMGNGAYATHATGGCNACNGGNAAYGGNTAYTCNGAYCARMGNTAYCCNCCNCARCAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY TCNAARAGYGTNATHAARTAYYTNYTNACNTCNCCNTCNGCNGGNACNCCNCARCARGCN CCNGCNTCNAAYGTNATHCARGCNTCNYTNCARGAYACNACNACNCCNCCN------CCN ACNAARCCNAARAARACNAGYAARAARATHAARTTYGAYGAY------GGNACNGGNGCN CCNCCNCCNAARAARAARGARAARAARATGAARATHGARATHATGTCNCCNTCNGARATH AARCCNCCNGTNTCNTCNGCNCCNCCNCCNGARCCNAARGCNCCNAGYYTNAARATGAAR ATHGTNTCNGGNTCNAAYCCNATGACNGCNCARGTNGCNATGGARGCNCARGAYGGNGGN GTNAAYAGYCCNGCNCCNCCNAARAARAARGTNACNAARAARGTNAARAARGARGTNAAY ------GARGAYGCNAARCCNGAYATH------------------CCNCCNGCNCARCCN GAYGGNGAYGGNGARAARGTNGTNAARAARAARAARGTNTCNAARAARAARGARAARYTN ATHCARAAYGCNATHAGYGCNGCNAARCARATHCCNAGYYTNACNGCNYTNGTNTCNACN CCNCARGGNCARACNGTNACNYTNGGNGAYTCNCCNTCNCCNYTNCCNGTNAARGCNAGY AAR------AARAARGCNAARMGNGCNTCNTCNCCNGTNAARAGYGARYTNAAYACNAGY GAYTCNYTNGTN---------ATGGAYTTYGAYGAYACNGGNATGGARGAYGARATHACN YTNGTNATHGCNGARACNGARAARAARAARAARAARGTNTCNGCNAARAARAARAGYCCN AARGAYAARGARGGNGTNGAYGCNTCNAARGGNGARAAR---GCNAARAARATHCCNAAR MGNGCNCCNACNGCNTAYATGYTNTTYTGYAAYTCNCAYMGNCCNGCNATHGTNGCNGAR AAYCCNGGNATHGARTTYGCNGGNATHAGYMGNAARYTNGGNGARYTNTGGCARACNCAR TCNAAYAARCARAARYTNCARTGGMGNMGNAARGCNCARMGNMGNYTNAARAARTCNAAY YTNATHTCNACNGGNAARACNGGNGGNAARGARTCNCARGGNGGNGCNGGNGGNCCNATG ACNGCNATHGGNCCNCCNATHATHCCNACNAGYAARAARYTNCCNYTNATGYTNCARAAR AGYGCNCCNGCNGTNGTNGAYGARGGNCCNYTNAGYCCNACNAARAAYTTYAGYATHGAR CCNYTNGAYGTNGCNGCNCAYYTNAARYTNYTNGGNGARTCNYTNAGYATHATHGGNATG MGNYTNCARGARCAYAARGGNATGATHGCNGTNCARGGNAGYYTNTCNGTNYTNYTNGAY TCNYTNYTNTGYGCNTGYGGNCCNYTNYTNTGYYTNACNCARCARGTNCCNGGNATGGAY GGNTGYTCNCCNTCNGTNCAYGCNCARACNYTNGAYAGYGTNGCNTAYGTNATGCCNGGN YTNGARYTNTGYGCNTAYGCNGTNCARTCNGARYTNGGNAAYTTYGAYCCNTGYMGNAAY ACNCCNGGNTAYGTNTCNGARTTYAAYTTYATHCCNAAYCARACNGARGARYTNGARGAY MGNATHGCNGCNATGCAYMGNMGNTGYATGGGNGCNACNCCNYTNATGGCNGARCAYMGN TTYYTNGARAARTCNAARTGGYTNGARATGTAYGGNGTNGAYYTNCAYCCNGTNCARGGN GARAGYTGYGTNGARTAYTTYYTNGGNYTNACNCCNACNGGNATHGTNGTNTAYAARCAY AARACNAARGTNGCNAGYTAYTTYTGGCCNMGNATHAARAARGCNTCNTAYAARAGYAAR ATHTTYATGGTNAARGTNAARGAYAARAGYAAYGAYGARCAYGTNTAYGCNTTYGARYTN TCNTCNAARTCNGCNTGYAARCAYYTNTGGAARTGYTGYGTNGARCAYCAYGCNTTYTTY MGNMGNCARCARMGNMGNGTNAAYTCNGARTCNMGNYTNAAYGCNCAYCARYTNTAYGAY AAYTCNGARAGYGGNTTYATHACNYTNATGGGNCARGCNCARCCNGTNMGNGCNTCNMGN CAYMGNTCNYTNCCNGARYTNCARGGNAARGARTCNCCNMGNAGYGTNAARTCNGCNCCN TGGGARTCNAARTTYGAYTTYGGNYTNTAYACNTCNGGNCAYGARTCNGAYCAYGGNCAR CAYCCNMGNMGNCCNMGNGCNATGTCNGGNAGYGAYAGYGARAGYGGNATHAGYCARMGN AARAARTAYTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TAY GGNTAYGGNTAYTAYCCNTCNAAYTAYAAYTAYGARAARTAYGGNATGCAYTTYAGYTCN CARCCNTCNYTNGCNMGNTCNGGNAGYMGNGAYGGNAARTAYCCNCCNGGNMGNYTNAGY CARATGAAYGGNAAYGCNATHYTNAAYGGNCCNCAYGAYYTNTTYGARCCNTAYTAYCAR CARGGNTCNMGNMGNGGNTGYCARGARMGNGAYTCNCAYMGNGARGTNMGNAAYGGNGAY ACNAARGAYAARGAYAARGCNTCNGARAARGAYMGNCCNTTYAAYGAYGAYTTYCCNTCN YTNAAYGGNTCNGGNGARTCNTCNGCNGAYTCNAARGCNAARCCNGCNTCNGGNGTNTGG GARAAYCCNCCNAARTCNTCN---AAYMGNAAYGARGARTCNACNGAYYTNYTNAARAAY ACNTCNCCNGGNATHTAYAARGCNYTNGTNCCNAGYAARAGYGTNCARCCNAARAARCCN GTNAARGAYGTNCCNMGNGTNAAYGGNAGYGTNMGNGARATHTCNCCNYTNAGYCCNTCN AAYAARACNGGNCAYMGNGARGGNTCNMGNTAYAGYCCNACNCCNGAYYTNGCNATHTTY ACNCARCCNAARAARYTNGGNGAYAARAARAGYGAYTTYYTNMGNGCNATHMGNAAYGAR AGYTCNATHMGNAAYGGNGARGTNTGYCARAAYCARAAYCARAAYATGGAYMGNAARTCN GARYTNAARCCNGAYTCNAAYGAYAAY---GCNAGYGAYGAYAGYTCNGGNTAYAARCAY ATHAAYGGNGAYMGNCAYGTNGAYACNAAYGARAAYYTNGTNAAYATGAARAARGGNAGY GTNAAYGGNGARGTNAARGAYGARATHGTNAAYGGNGAY---------GCNYTNATHAAY CAYGTNGAYCAYATHTCNYTNTCNGGNGARGARGARGARMGNMGNYTNYTNYTNTCNATG GGNTGGGTNGARGARGAYAAYACNGARTAYGARATHACNGARGAYGARATHMGNGARTTY CARAAYYTNYTNYTNAAYCAYTGYCAYGGNCARAARAAYGGNYTNAARTCNTCNYTNMGN AGYGCNYTNGAYMGNAARYTNGGN------ACNGAYGAYATGYTNAAYGGNATHTCNTCN GCNGARGARAAR---------------ATGACNCARAARGCNTAYTCNTCNGGNTCNCAR TAYCCNGARYTNAARCCNGAYACNYTNMGNYTNTAYAGYTCNMGNYTNTGYCCNTAYGCN GARMGNGCNMGNYTNGTNYTNGCNCAYAARAAYATHCCNCAYGARGTNGTNAAYATHAAY YTNGGNGAYAARCCNGARTGGTTYYTNGCNMGNGCNCCNYTNGGNAARGTNCCNGTNATH CARCAYAAYGAYATHATHYTNTAYGARTCNACNGCNGTNAGYGARTAYYTNGAYGAYTCN TAYCCNGGNGARAARYTNCARACNCARGAYCCNTAYCARAARGCNGTNGAYMGNATHYTN YTNGARGCNTTYGGNCARYTNTCNTCNGCNTTYTAYGGNATHYTNTTYGGNATHAAYAAR GARGARAARAARGAYGAYGTNTAYAARGCNTTYGGNTTYTAYGARGARGARYTNTCNAAR AARGGNACNAARTAYTTYGGNGGNGAYAARCCNGGNATGATHGAYTTYTTYATGTGGCCN CAYYTNGARMGNGTNCCNTCNGTNACNAARATGGCNCCNCAYATHTCNYTNGAYAARACN AARTTYCCNAARYTN---GCNTGGTGGGAYGCNATGACNAAYGTNCCNGCNGTNAARAAR GARATGCAYGAYATHAAYTGGCAY------------------------------------ ------------------TTYGGNMGNTAYCCNMGNGARTAYAAYCCNAARGTNCAYGGN CCNTAYATGCCNGGNMGNTTYTAYGGNAARCCNGAYACNCCNYTNGGNCARGTNAARYTN GGNGARYTNGGNGCNTGGYTNGGNMGNMGNAAYAARACNCCNGARGGNATGTGGAGYGCN GTNCAYMGNACNTAYTGGMGNTGGGCNGCNAAYAAYYTNCAYGTNMGNAARAGYGGNTTY GTNCCNTTYGGNCARGCNGCNATGGTNYTNTCNATHACNTTYTTYTTYYTNYTNTAYAAR GARMGNAGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARGARGARCARATHAAYTCNYTNGARTAYACNYTNGARGARACNAARAGYGAYGTN GARATGMGNCARTCNACNATHGAYCARATGAARTCNGAYYTNGCNATHACNCARTCNGAY YTNACNCARGCNMGNGARGAYAARAGYGCNGCNYTNAARGARATHGAYMGNYTNGARCAR CARAGYCARCARYTNCARYTNAAYYTNGCNTCNGCNCAYCARMGNCAYAARAGYGARACN TGYMGNTTYGARGARCARGTNTCNTCNYTNGARMGNCARATHTCNGARACNCARGGNAAY YTNMGNAGYGCNGARTGYGARGTNAAYAAYAARGARGARCARATHAARMGNAAYGARGCN GARATHGCNTCNTGYMGNGAYGAYATHMGNAGYAARGTNGARGARATHGARMGNYTNGAR MGNACNYTNCAYGARGTNMGNYTNGARATGAAYCARACNAAYGCNCARTGYAARCARYTN GARAAYGTNATHGCNGARYTNAARTCNGAYGGNGARAAYYTNMGNAARGAYYTNAAYGAR GCNMGNYTNCARTAYAARGAYTGYGCNCARGARYTNGCNCAYCAYGARGARAARYTNAAY YTNATGGARCAYAGYYTNCARTCNACNCARGAYCARYTNAGYCARMGNGTNACNGARATH GTNMGNCAYGARCARAAYACNMGNAARYTNCARGTNGARYTNAARGCNATHAARGARMGN GCNGARGCNTAYGARGARGARATGGARGAYCARAARGGNATGATHGAYAARYTNMGNAAR GAYYTNGTNYTNTCNAARGARGARTAYCAYGCNTCNGTNCARGARGGNATHGCNTAYAAR CARCARGCNCAYAARAAYGARYTNGARYTNAGYGGNAGYMGNGARCARGARAARATGYTN TCNGAYCARGTNGARCARCARGARCARATHYTNAAYCARYTNCARACNGARYTNMGNGCN GARMGNGARMGNCAYGGNGAYACNGTNCAYCARYTNAGYGCNAGYAARAARAAYGGNATH GAYYTNCARGCNGAYYTNGARGCNATGCARAARCARGTNMGNGARYTNCARGAYMGNGTN AARGCNMGNGARGARACNATGGTNMGNYTNMGNCAYGARATHGAYAAYATGCAYCARAAR AAYMGNGARAGYAAYGARATGATGGCNGARAARGAYGGNCARYTNMGNYTNGCNGARATG AAYYTNCARACNGCNCARAARCARGCNAARCAYCAYGCNCARGARATHGCNMGNTAYGAR GAYACNYTNGCNCARYTNCARACNGAYCARGARAARYTNCARGARCARTAYGGNCAYTCN TCNTCNAAYYTNATGGARGCNGAYAGYAARGTNCAYGARYTNAARGTNCARYTNACNACN YTNCARGGNCAYCAYAARGARGCNATGGAYCARYTNACNGAYAARGCNMGNCARYTNGCN GCNATHAARACNGARGCNGCNAARATGGCNCARCARAAYAAYTCNATGAARGAYGARATH ATGATHTAYGAYGARAARGTNMGNMGNYTNCARCARGARYTNMGNAARTCNCARGARATH AAYAARGCNACNGARGARGARYTNCARCAYTTYGARGARMGNTAYACNAGYYTNCARGTN GAYYTNGTNACNAGYCARGARAARCARAARCAYTCNYTNCARGARYTNTCNTCNAARGAR GARGARAAYGTNGTNGTNAARGTNGARYTNAGYTCNYTNCARGARAARTAYAARGCNGTN AAYGAYGARGTNCAYAARYTNACNAGYGARYTNGARYTNACNAARCARAAYTAYMGNAGY GCNACNGARGARATHTCNGGNYTNMGNGTNGCNYTNGARGARTCNMGNGCNAAYGGNGAY MGNYTNCAYMGNGARAGYGARYTNGTNGTNCAYAAYGTNAAYACNTGGGTNCARGARCAR AARATGGCNAAYGARAARYTNGGNAAYAARATHMGNGARCARAGYAARTCNATHATGGCN YTNACNTCNGARAARGARACNYTNYTNGARCARGTNTCNAARYTNCARAARAAYTAYAGY AARACNMGNACNGARYTNGARGAYAARACNATHGARGGNGARAARYTNMGNGCNYTNCAR TCNCAYTCNGCNCAYCARCARGTNGTNYTNAAYCARYTNAARAGYMGNYTNGARGARCAY GARYTNGAYAARGAYTCNGAYYTNAARACNAARGTNGCNACNATHGARGAYYTNCAYCAY MGNYTNAARTCNAAYATHGARAGYATHCAYCARYTNAAYCARCARYTNAGYACNYTNCAR AARGAYAAYATHMGNYTNMGNAGYGARYTNGAYMGNGARATHTCNACNMGNCARAGYYTN GARATGCARGTNCARGGNAARGAYCARYTNGTNGARTCNYTNMGNTCNCARYTNGAYTCN AAYTCNTAYAARAARYTNYTNGARAARGCNGARAGYTAYAARGAYCCNGARAARYTNGTN MGNTCNACNYTNAGYAARACNGCNGAYGARACNGGNGTNGCNGAYCCNCAYAAYYTNGAY AARTCNTAYTGGATHCARMGNGTNGGNGARAAYAARYTNTCNATHCARYTNCARCARAGY AGYGARTAYTGGTCNGAYAARGTNMGNGAYYTNTCNGARCARYTNGARAARACNMGNACN ATGTCNACNGCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNAAYGAYYTNAAYACNAAYTCNACNAARTCNMGNCCN AAYTCNATHYTNTCNCCNAAYTCNGARTTYGTNGCNYTNGCNGAYAAYATHGARCARYTN GCNAAYAAYATHAGYTTYGARTAYGARGAYAGYTTYGAYACNTCNYTNGARAGYACNGCN GCNTCNAAYMGNGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGCNTCNACNTCNCCNAARCCNAARAARGGNATHYTNAARAGYTCNAAYAGYATHGAY CAYAGYAARAARGARATHGARTGGGAYGARATGAAYATHYTNGCNACNCAYCAYCCNCCN GAYAARGAYTAYGGNTTYATGAARGTNGAYGARCCNCCNACNCCNTAYAGYMGNTCNGCN ATHTCNGAYAAYGARGAYGARGARTCNAGYMGNGCNMGNMGNTCNAGYGTNGARMGNGAY TCNGGNYTNGAYCCNGAYGAYYTNGCNTCNMGNYTNCARGAR------GGNAGYGAYAAR AAYAARACNTTYGCNGAYGAYGAYGAYGAYAGYGAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYYTNMGNATHAAYCARTTYGAYATHGGNGAR ACNATHGCNCARMGNMGNMGNMGNGCNGGNGTNTTYAARAGYCARTCNGGNCCNCCNCCN GARMGNMGNAGYACNATHAGYAGY---ATG---ACNAGYAGYTAYCARGTNACNMGNATG MGNAAYYTNTCNGGNGGNAGYAGYGGNAGYACNGCNAGYGGNAGYAGYAGYGGNAGYTCN GTNCARYTNGAYAAYCARTAYTCN------TCNACNGAYACNAAYYTNTAYTTYAAYTGY TAYATHCCNTCNATHACNAAYTCNACNTCNACNGTNCCNMGNAAYGARGAYTCNAAYTCN TCNTCNCAYMGNAARYTNGAYMGNAGYYTNAGYGAYAGYGAYAGYGAYMGN--------- ---------------------------TCNGGNAGYMGNTAYAARACNGARYTNTGYMGN CCNTTYGARGARAGYGGNTCNTGYAARTAYGGNGAYAARTGYCARTTYGCNCAYGGNTCN CAYGARYTNMGNAAYYTNGCNMGNCAYCCNAARTAYAARACNGARYTNTGYMGNACNTTY CAYACNATHGGNTTYTGYCCNTAYGGNCCNMGNTGYCAYTTYATHCAYGARGAYGAY--- ------AARGGNGARGCNTCNCCNAAR--------------------------------- ---CARAGYGGNAGYGGNAGYAGYAGYCCNTCNYTNAGYCCN------ACNYTNAAYGAY CARAGYAAYTTYTCNTAYTCNTCNGARTCNTCNCARYTNAAYATHGARAAYACNCARATH AAYAAY---------TCNYTNACNGTNAAYATHAAY---TAYGGN---------AAYGTN GARYTNCARTCNYTNGAR---CAY---CARTTYTCNGCNYTNAAYATGAAYMGNAAYTGY ------AAYGARTCNTCNMGNAAYGTNTTYAAYAAY------------------------ ------AAYAARTCNGAYGARTAYGAYATHTTYAGYTCNATHTCNGTNTTYAAYGCNGAY GARGTN---GTNGAYAAYGCNCAYCCNAARCCNTCNAAYTCNTAYCCNTCNCAYTGYAAY CARAGY------YTNGAYAAYTAY---TCNATHTCNAGYTCNCAYTTYGAYTGGCCNTCN ACNATGTCNTCNCARAGYATHGCN------CCNGTNGAYCCNATHAAYTAYTCNCCNACN GGNTCNACNGGNTCN------------------------TCNAGYTCNGGNAGYGAYTGY AGYGGNAGYACNGARAGYYTNGTNAGYTCNGGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ACNGCNATHAARGAYAARAAYGGNACNNNNYTNAAYGAYCCNGARAARATHTCN AAYMGNTGGGCNGARTAYTGYGARGARATGTAYNNNAGYGAYAGYAGYNNNAAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNYTNGGNGARGGNGARGTNTCNGTNCCNACNCAYTTYTTYAARGTNATHATH ATHGARACNYTNGAYGGNAAYYTNGARYTNGARTCNTAYATGATGCCNAAY--------- AARGARYTNGAYGAYAAYAAYYTNGAYAARTAYYTNACNCCNYTNTGYAARATHGARCAY TAYTCNGGNYTNATHTTYTTYCCNGARAARAARGTNTGYTTYACNAGYAAYAAYAARMGN MGNGGNGCNATGYTNCAYGCNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGNAAYTAYMGNCARYTNGARAARGGNMGNATHGTNGTN TAYGCNACNTCNATGAGYGTNGTNMGNGARACNAGYGARMGNTGYAARTCNGTNMGNAAY ATHYTNCARAAYCAYATGGTNMGNTAYGARGARMGNGAYYTNTAYATGAGYMGNGARATH CARTCNGARYTNAARCAYMGNYTNAGYCARGARGGNATHGAYCARATHAARYTNCCNCAY ATHTTYGCNGAYGGNATHMGNATHGGNGGNGCNGGNGARGTNGARMGNYTNAAYGARGCN GGNGARYTNMGNGCNYTNYTNGAYGGNTAYCARAARGTNAAYGTNMGNTTYGCNTGYCAR TCNTGYGGNGGNTAYMGNTAYGTNCCNTGYGAYGTNTGYCAYGGNAGYAARMGNTCNYTN ATHMGNAAYCAYTTYACNGARGAYTTYTTYGCNYTNMGNTGYATGCAYTGYGAYGAYCAY GGNYTNAARMGNTGYGARYTNTGYAARGARCARCARGAR---------TAYTGYAARAAY ATHYTNYTNAAYCARGTNGTNGARYTNAARTCNATGYTNAGYYTNTCNTCNTAYAARYTN GCNMGNGTNTAYGGNATHACNCAYATHMGNATHYTNCAYATHAGYACNAARAAYAAYGCN CARTCNGGNGCNATHGCNGARTCNACNAARTTYAAYATHTCNAAYATHCAYAGYGARGTN TTYCAYGTNYTNACNYTNGAR---ACNCARAAYATHYTNGARYTNGGNGGNYTNGARACN GARTTYGARAARATHAARMGNYTNTTY---TTYGTNAAYAARTCNACNACNAARYTNTAY MGNCCNCAYGGNATHYTNYTNCAYGGNCCNCCNGGNTGYGGNAARACNTCNTTYGCNMGN AGYYTNGCNAARAARTGYGGNGCNATHTTYTAYAAYGTNGARTCNTCNGAYYTNYTNACN TCNGARTTYGGNAGYGGNGCNAAYGCNYTNMGNAAYGTNTTYCARAARGTNGTNGCNYTN ACNGARGARGGNCCNGTNATHYTNTTYYTNGAYGARATHGAYATGYTNTGYCCNMGNCCN GARACNGCNAGYYTNGGNAAYMGNCARYTNTGYAAYGCNYTNACNACNGARATGGAYGAR ATHCAYAGYAAYAAYACNTCNTGYYTNYTNATHYTNGCNGCNACNAAYTCNGTNTCNAGY GTNGAYCCNTGYYTNMGNMGNCCNGGNMGNTTYGAYCARGARATHYTNATHAAYGTNCCN TCNGARTCNCARMGNTTYTCNATHYTNCARGTNYTNACNGCNGAYYTNATHYTNGCNCCN GAYGTNTCNTGYAARGCNYTNGCNCARATGACNCCNGGNTTYGTNGGNGCNGAYYTNMGN GGNYTNTGYGARGAYGCNGTNAAYCARGCNCARAAYMGNCAYCCNGARGARCCN------ ATHGCNYTNAGYATGGAYAAYTTYTAYCARGCNYTNCAYAARATHATHCCNTCNYTNAAR AARGGNACNGARTGYGTNGTNGAYTTYAARCCNGTNAARTGGGAYGAYATHGGNAGYYTN GAYGARATHAARGCNGARATHAARCARTCNATHGARTGGCCNYTNAARTAYCCNGARATH YTNCARAARATGGAYATHCCNCCNGCNAARGGNATHYTNYTNTAYGGNCCNCCNGGNTGY TGYAARACNACNYTNGTNMGNGCNGCNGCNACNTCNTGYAAYGTNTCNTTYYTNTCNYTN AGYGGNGCNCARGTNTAYTCNGCNTAYGTNGGNGARTCNGARMGNYTNATHTCNCARGCN TTYCARAARGCNMGNGCNYTNTCNCCNTCNATHYTNTTYTTYGAYGARATHGARTCNYTN GTNGGNAARMGNACNGCNAAYGTNGGNAAYAAYMGNGTNCARGARMGNATHYTNTCNACN ATGYTNAAYGARATGGAYGGNGTNGGNAAYAARYTNGAYTTYAARATGGAYTCNAGY--- ------------------ACNCCNACNAARACNTCNGGNGGNCAR------AARACNATG GARAGYAGYGCNGGNAGYAAYGCNAGYTGYCCNCCNGTNTGYGAYTCNAGYATHGAYGTN ---AGYYTNAARGTNATHGTNGTNGGNGCNACNAAYMGNCCNGAYATGYTNGAYCCNGCN ATHYTNMGNCCNGGNMGNYTNGAYAARCAYGTNTAYGTNCCNCCNCCNGAYAARCARGCN MGNAARGCNATHYTNGGNATHTAYTCNTCNAARATGTCNTGYCAYGARGTNGAYYTNGAR ATGYTNGTNAAYAARACNGARYTNTAYAGYGGNGCNGAYYTNAARAAYGTNTGYAARGAR GCNGGNYTNCARGCNGTNMGNGARCARYTNTCNAARAAYGAYGAYTCNAGYAGYYTNGTN GTNACNCAYAAYCAYTTYGARGARGCNYTNAARAGYGTNAARGCNTCNYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MGNGARMGN GAYGARYTNYTNGCNYTNYTNGAYGTNTCNGARMGNATGAARTAYGARCARGGNAARAGY ATGATHGAYGARGARGARTAYGGNTCNTTYACNTCNACNGARYTNGCNGTNYTNGGNGCN TGYAARTGYMGNGGNGCNAAYCCNGARCCNTGYGGNTGYGCNCAYGCNGCNGCNAAYYTN MGNAARGARGTNGTNAARYTNMGNGARGARATH--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AAYATHGTNACNTGYGGNGGNYTNYTNGGNGTNGGNGCN TTYGTNGTNCARAARATH------------------GGNTCNCAYGARTAYGAYTAYGCN MGNACNGGNMGNATGATHACNGTNGGNTTYTGYYTNGGNCCNTTYAAYCAYTAYTGGTAY TCNTTYYTNGAYAARGCNGTNAARGGNTCNGGNATGACNATHGTNNNNAARAARATHATH TGYGAYCARYTNGTNGCNGGNCCNTTYTTYTGYACNACNTTYYTNTCNGGNATGACNYTN YTNGARGGNAARGGNYTNACNGGNGCNTTYGARGARTGGMGNGCNAARTTYYTNTCNATH TAYYTNGTNGAYTGGGCNTTYTGGCCNGCNGCNCARTTYATHAAYTTYMGNTTY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNAARCARAARYTNCARCARMGNYTNGARCARMGNGARCARTCNATHYTNTTYAAR CARGAYGARGARATGCARACNYTNATHAAYAARGTNACNAAYAARAARCARAARATHATH CARGARCARGARYTNACNGARGTNGARAARGGNATGAGYGTNTTYYTNGAYGTNTTYMGN MGNGCNGAYAARAAYGAYGAYGGNTTYATHTCNTGGGARGARTTYGTNTCNTTYTTYGCN GAYGGNGTNATGGGNAARCARGARYTNCARGAYYTNTTYAAYGARATHGAYTCNCAYAAY ACNGGNAAYATHGAYATHGGNGARYTNTGYACNTAYTTYTCNCARAARYTNGGNAARTTY CARGARATHTTYGGNTTYGTNGARGARATGAAYAARAARYTNACNGAYGTNYTNTTYAGY ACNTCNAARATHTAYAARGAYTCNGAYMGNACNGAYAARTTYGTNACNMGNTTYYTNATG MGNGARGTNYTNAAYCARATGGGNGCNATGCARMGNCCNATGGAYGCNGCNTCNGARACN YTNGAYCARCARGCNMGNGAYGARMGNTCNGAYATHCARCCNYTNGARGTNGGNGAYATH GTNAARAARTCNGGNAGYGAYAGYGGNATHGTNCCNGGNMGNGTNGTNMGNMGNGCNAAR MGNCARGTNAGYAAYAGYAGYACNTTYGGNGGNTCNATHGARGARGGNCAY---CCNGGN CARAGYTTYYTNAAYGGNCARYTNGAYAARYTNGCNATGYTNGTNGAYAARYTNGARTGY AARATHAARTTYGARAAYTTYMGNGAYGARGARGTNGTNACNGCNMGNGAYGAYACNGTN YTNYTNGTNCARMGNGARTTYATHGTNAARAARGAYGGNATGGGNGARTTYMGNTCNCAR YTNMGNTCNTAYGTNGAYYTNACNCARGGNTTYMGNGGNTGYTTYAAYGTNAGYGTNMGN GAYYTNMGNGCNAGYCAYTCNTTYCAYGTNTAYGARGTNTGGTGYGAYGARGARCAYTAY YTNCARAAYTGYGGNAGYGARGCNACNACNTCNYTNGTNAAYAARACNGCNGAYYTNYTN GARAARCCNGARACNGTNAARTCNATGGTNATHCCNGGNGCNTGGTGG------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CARACNAGYAAYGCNYTNAAYAARTGY TGYATHGGNAAYACNTAYTTYGCNGGNTCNGCNGARCARGTNGARTGYAAYMGNYTNYTN YTNATHTCNTGYCARAARMGNCARGTNTAYATGAARGARATHCARMGNYTNAARGARACN TCNATHYTNGAYGCNTCNGGNCCNGGNCCNMGNGGNTCNYTNACNATHAGYGAYATHMGN YTNCCNYTNAARAARGAYTTYGTNAARAARATHGGNACNTCNCAYGAYAAYACNACNCAY TTYTTYATHYTNYTNATHMGNAAYGGNTGYCARATHATHTGYACNCARATGYTNTCNACN CAYGAYCCNATGATGMGNGGNAGYYTNGAYTTYCCNAAYYTNATHAARATHAAYGGNATH GGNGGNGAYTTYAARYTNGCNGTNGAYATHTAYGGNATGAGYATHTCNMGNGARATGACN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYTTYGGNTCNTCNGTN YTNGGNACNCARAARTAYTGGGARGAYGCNTAYGARAARGARYTNGARAAYTTYGARGAY TTYGGNGAYGTNGGNGARATHTGGTTYGGNGARGAYACNCARGAYMGNATGGTNAARTGG ATGTGYAAR---AARTCNATHCCNAARACNTCNAAYATHGTNGAYYTNGGNTGYGGNAAY GGNACNYTNYTNYTNGCNYTNMGNCARGARGGNTAYGTNTCNYTNACNGGNYTNGAYTAY TCNGARTAYTCNGTNAARYTNGCNAAYAARGTNTGYGARGCNGARGGNATHATHGAYATH ACNTTYGARGTNTGYGAYATHYTNTCNTCN------GAYGARGCNAGYAARCAYAARGGN ATHTAYGAYATHTGYYTNGAYAARGGNACNTAYGAYGCNATHAGYYTNAARAAYACNGCN GAYTCNAGYTAYMGNCARACNTAYATHAAYCAYGTNTGYTCNATGYTNAARTCNAAYGGN TGYYTNATHATHACNTCNTGYAAYTGGACNAARGAYGARYTNACNCARCAYTTYAGYAAR GTNTTYGAYGTNACNGAYGARATHCCNGCNCCNAARTTYACNTTYGGNGGNCARACNGGN CARAARGTNACNTCNYTNATHTTYACNMGNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYAAYAGYATGTAYGTNGTNGCNAAY ATGGGNAAYMGNGTNCCNTGYGAYCCNAARYTNGAYCCNAARTGYCCNCARGAYGGNMGN TAYCARTAYAAYACNGAYGTNGCNTTYGAYCCNCAYGGNAAYYTNGTNGCNMGNTAYCAY AARGTNAAYYTNTAYTTYGARCCNCARTTYGAYAARCCNCARCCNGARGTNATHTAYTTY GAYACNCCNTTYGGNMGNTTYGGNYTNYTNGTNTGYTTYGAYATHYTNTTYGARTCNCCN GCNGARTCNATGYTNAARGARTAYTCNATHGCNAAYATHGCNTAYCCNACNGCNTGGATG GAYGCNYTNCCNYTNYTNTCNGCNATHGGNTAYCAYTCNTCNTTYGCNMGNGGNGCNGGN GTNAAYYTNYTNTCNGCNAAYATHCAYATGCCNTCNYTNMGNATHCARGGNAGYGGNATH TTYACNCCNGARGGNGCNGCNAARTTYTAYTAYAAYAAYGAYCCNAARTCNACNGGNAAR YTNYTNGTNTCNACNYTNGAYATHYTNGGN------------------------------ ---TCNAAYGGNAARGAYAAYATHGCNGAR------------------------------ ------------------------------------------------------------ ------------------------CCNTTYAAYGCNGCNAGYGARGARTTYTAYTCNAGY YTNYTNCAYGAYCARTAYACNTTYAARATGYTNGARAGYCCNTCNGGNGARGTNCAYGTN TGYAAYAAYAAYYTNTGYTGYTCNYTNAAYTAYACNATHTCNAAYGCNAAYAAY---AAY AAYYTNTTYGCNYTNGGNGCNTTYGAYAARYTNCAYACNCAYCAYGGNMGNTAYTAYYTN CARACNTGYGCNYTNGTNAARTGYGGN---AAYAAY---AARGAYAARTCNTGYGGNCAY TAYACNTTYGAYTCNGARATHAARTTYGARTCNYTNTCNYTNACNGGNACNTTYCARACN AARTTYGTNTAYCCNCARGTNGTNATGGTNGARAAYAARCARYTNTTYYTNGGNGCNCAR CCNTCNTGGAGYTTYCARGAYAAY---ACNYTNMGNTCNAAYGGNGGNYTNGAYAARCCN YTNYTNACNGCNGCNYTNYTNGGNMGNTTYTAYAGYGARGAYAGYGAYTCNGGNAGYGAR GAYGTNGGNYTNACNTAY------GAYMGNAGYMGNAARATGAAYGGNCARYTNGAYGAY GAYGTNTGYMGNGAYTAYATGMGNAAYACNTGYACNMGNGGNAARAAYTGYMGNTTYMGN CAYCCNGTNGCNGARGARCARGCNGAYCCNCCNCCNMGNMGNGAYATHACNTTYTGYCAY GAYTAYCARAAYAAYGGNTGYACNMGNGGNAAYTGYAARTAYYTNCAYTGYACNMGNGAY GARCARGARTGGTTYCAYAARACNGGNYTNYTNCCNYTNMGNYTNAAY---CARCCNATH GGNTAYGGNAGYCCNACNCAYMGNGTNGARGCNCCNYTNTGYAARGAYTAYYTNCAYGGN GAYTGYAARMGNGGNGGNAARTGYMGNTAYMGNCAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TCNGTNACNATHGARGTNACNGCNATHCCNCCNGAYGCN CCNCCNGARGTNACNGTNAAYGGNGTN---CCNATHGTNAAYGGNCARGAYGTNACNGTN AAYYTNGAYMGNACNYTNAAYGTNMGNTGYAAYGTNGAYGGNGGNCAYCCNGARGTNAGY AGYGTNACNYTNGTNTGYACNGGNATGGAYGCNACNACNCAYGAYGGNACNYTNGTNACN ---AARAGYTTYAGYGCNACNGARGAYATHAAYCARGCNCARTGYGTNTGYTCNGCNACN CAYGAYTCNGGNYTNTAYACNCAYACNACNTCNTTYATHATHGTNATHCARGARCCNCCN TCNATHATGAARTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYATHATHAARMGNGGNAARTGYYTNATHGGNCARCAYGCN GARATHATHGCNACNCCNTTYGGNTCNYTNTGYCCNACNGTNTTYTTYAAYGGNTAYAGY MGNGGNGTNATHAGYAAYGTNAAYGGNGTNAAYGAYTGYTGGATHGTNTCNGAYGCNMGN TGYATHCCNGTNTGYGARGTNGGNCCNYTNTAYACNAARMGNAARYTNACNGAYTCNAAR AGYTTYYTNACNGGNGTNATHGCNTCNACNYTNTGYTGGAARAAYAAYGARTGGGTNGGN TTYTCNATHGCNTGYAGYATHGAYAGYGTNYTNCARTCNATGACN---CARYTNAARTCN ATHTAYCCNGARAAR------------------------ATHYTNAARCAYCCNAARTCN ACNMGNAARCARAAYMGNAAYGAYMGNACNACNAARGGNYTNCARYTNGCNCARTCNATG ACNGTNGTNATHCARACNGAYACNTCNTGGGGNTCNGGNGTNATHATHGAYMGNGAYAAY GGNATHATHYTNACNTGYAGYCAYGTNGTNAAYGGNGCNAAYGTNAARTCNGTNMGNATH ACNCCNTCNAAYAGYACNAAYCAYTAYGGNGCNATHGTN---TAYMGNCARAAYCCNYTN CARACNCCNTAYGAYYTNGCNGTNATHAARTGYYTNCARGCNACNMGNCAYYTNCCNMGN GGNTGGMGNGTNAGYGTNGCNGARGCNTGYYTNGGNGARGAYATHTTYATHTCNGGNCAY GCNGCNTTYGGNACNGARGCNCAYYTNCARCCNTCNATHTGYCAYGGNGTNGTNTCNAAR GTNYTNMGNAGYGARAGYGARCCNGTNATGATHCARACNACNTGYGCNGTNCAYCCNGGN TCNAGYGGNGGNCCNATGTTYACNYTNGAYAAYCARYTNGTNGGNATHATHCARAGYAAY ATHAGYGAYGCNAGYMGNAARATHTGYTAYCCNCAYYTNAAYYTNTGYATHCCNATHTCN ACNYTNTGGCCNATHATHTCNMGNTAYYTNCAYAAYGGNGAYAARCARGTNYTNTCNGGN YTNCARGTNCARAAYGAYGARYTNAAYCARYTNTGGACNYTNATGGGNGTN--------- ------TCNYTNGAYGARTTYATHMGNCARAARAAYGTNAARGTNCARATHMGNAAYACN CARCARAAYCARCCNMGNGGNCARCARCARAAYCAYMGNAARGGNYTNGGNGTNACNCCN AARTTYCARACNAARCCNGTNCARMGNACNTTYGAYGCNMGNTCNAARYTNGGNCCNAAR ACNGTNGTNGAYGCNMGNGAYAARATHATHATHAAYAARAARAGYGGNAARGGNGAYGCN MGNAAYAARATHGTNCARAARCARGTNCARAARGGNACNTTYGAYGCNMGNTCNYTNYTN AARAAYCARAARCARGCNAARAAYAARCARAAYGGNCCNCARGGNCCNCARTTYGGNTTY CCNGGNGTNCAR------------------------CCNYTNACNMGNACNYTNTCNAAY CCN------ATGGGNCARATHGGNAAYATHCARGTNACNMGNCARATHCCNGGNACNGAR GTNACNYTNACNMGNGAYTCNATGCARATHACNAARMGNTCNGGNCCNCCNCCNYTNTCN GCNAARTCNATHGGNGAYACNGTNCCNATHATHCARATHMGNAAYGAYMGNTAYCARCAR CCNCCNCCNCCNCCNCARCCN------------CCNTCNTGGCCNAGYCARCCNCCNCAR CAYGTNCCNCARCCN---GCNCAYATGGGNATHCARTAYTCNCAYCAYGGNAAYTCNTCN GCNMGNCCNTCNTAYATGTCNTCNTCNCARTAYAAYMGNTAYCARGAYTTYGAYAAYCCN GARTAYAAYAAYAARGCNTCNGTNGGNGTNCAYAAYATHCCNAARATGCAYATHTCNAAY ATHAARTCNGTNGARGCNGCNGGNATGMGNCCNGTNTCNTCNTCNTCNACNMGNTCNMGN CARGCNCCNATHCARCCNMGNGCNCCNCCNGGNGCNGCNACNGTNTCN------------ GCNAARCARCCNATHTCNYTNTCNCARCARTCNTCNGGNGCNYTNAARMGNMGNCAR--- CCNCCNGTNACNCARGARGTNGGNGGNCCNYTNMGNYTNGGNAARGGNGGNGGNCCNGGN YTNCARGTNGGNATHGGNGARGTNTCNCCNCCNAARMGNGCNAARCCNGGNGCNAAYCCN ------ATHGARCCNATHGARATHATHGAY---GARGAYTTYTCNAARTTYGTNAGYCCN ATHCARGGNTTYMGNGTNGTNGTNACNAAYYTNTTYTCNGGNGTNACNCARGAYGAYATH ATHGARYTNTTYGGNGTNGTNGGNCCNYTNAARAARGCNMGNYTNYTNAARGCNGGNTCN GCNGARGTNGTNTAYACNGTNMGNGARGAYGCNGCNAARGCNGTNCARAARTAYCAYGGN MGNGARYTNGAYGGNCARCCNATGTAYGTNAARATGACNACNCCNYTNACNGCNGTNGTN AARACNCCNCARGGNCAY---GAYCCNGAYATHACNGGNGARGCNYTNAARYTNTAYAAR AARCCNAGYAGYYTNGGNGCNYTNCCNGARGGNCCNATHGARGTNCCNACNATHCAYMGN GCNYTNTTYAARGTNGGNCCNCCNGCNCCNAAYAARTCNGTNAARTTYACNGTNAARATH ---------------------CAYYTNYTNMGNAAYAGYATHYTNTCNCAYCARTGGGCN GAYGCNATHAARGTNATHCAYACNYTNGCNAARGARAGYAGYATGACNGARATH---ATH TGGAARGCNGGNATGACNTCNYTN---ATGGARAARAAYACNAARGCNGCNGAYYTNTAY TCNMGNCARYTNTGYGAYTGYCCNAARGTNACNMGNATHGARGTNTTYTAYGARTAYYTN YTNTAYYTNYTNACNGARGGNAAYYTNGARAARGCNMGNAGYYTNACNCARGAYATHGTN GARGCNGARGARATGCARACNGCNGAYACNGAYTAYYTNMGN---------YTNYTNTTY MGNGCNTAYATGGGNYTNATHGAYTAYATHCAYTGGAARATHGARATHTCNCARGARGAR GARGARAGYTCNGTNGTNGAYTTYATHTCNTCNCARYTNTCNCARGGNYTNTCNCAYMGN ACNTCNAARYTNAARGCNGARAARGCNATHCAYAAYYTNTCNTGYGTNMGNGAYATGCCN GGNGTNTGGGAYATHTTYATHGTNAARATHGTNGARATGCAYGARTTYTAYAAYGARYTN GARGCNGCNAARTCNGTNYTNMGNGAYTAYATHTCNAARAAYCCNGAYAAYYTNAAYGCN CAYMGNTAYYTNTAYAARTAYGARATGAARCAYAARGARAAYACNGAYGARAARYTNCAR AGYATGAARAAYATHATHCAYYTNGAYCCNAGYAAYTCNYTNGCNYTNGARYTNTAYMGN GARYTNGARTCNTCNGAYCCNGGNGCNGTNGCNATHYTNTTYGAYTAYYTNGAYTTYAAY CAYTGYAARAAYGAYATHCARGCNTGGAGYTTYYTNAARACNCAYYTNGARAARGTNGGN AARAARAARCARTGYCARGARGCNGTNTCNAARTGYTGGGTNCCNMGNAARGAYTGGTGG CCN---------------GTNGTNTGGGTNYTNYTNGTNTTYGTNGAYTGY--------- ---AARAARTCNCARGAYTGYTCNACNTGYAARGARATHGTNGAYAAYTTYCAYAARGGN YTNYTNGCNACNGCNAARTCNAAYTAYGGNGGNGGNAAYACNAAYTGGGARGARAARTCN YTNGGNTCNTAYGCNTTYAGYGARGTNMGNYTNGTNGARATHGTNGARAAYYTNTGYAAR GAYAARTCNAARGARTGYCAYACNATGYTNGARAARCAYGARGAYYTNGTNGARAGYTAY TGGTTYAARGARTTYGCNAARAARACNAAYAARGAYTTYCAYATHTTYYTNTGYATHGAR AAYATHAARGCNTGYTGYCCNAAYGGNACNTAYGGNAARGARTGYAARCCNTGYCCNGGN GARGTNGAYMGNCCNTGYCAYGGNAAYGGNAARTGYGAYGGNGAYGGNACNMGNGGNGGN AARGGNAARTGYMGNTGYAAYTCNGGNTAYACNGGNGAYYTNTGYAAYGARTGYAARGAY GGNTAYTAYGARGAYAGYAARAAYGARACNCAYAGYYTNTGYAARGTNTGYCAYATHTCN TGYAARGGNTCNTGYACNGGNGARGGNCCNAARYTNTGYGGNGARTGYAARGAYGGNTGG YTNYTNGAYCCNCARCARGGNTGYAARGAYATHGAYGARTGYYTNGARGARCCNTGYGAY GAYGAYCARTAYTGYGCNAAYACNATGGGNTCNCAYTCNTGYTTYAGYTGYAAYGCNGCN TGYGCNTCNTGYACNGGNTCNGGNCCNGAYAARTGYAAYGARTGYAGYAARGGNTAYATH AARYTNGARAGYGGNAAR---TGYGARGAYCARGAYGARTGYAGYYTNGAYCCNACNYTN TGYACNAARACNAAYGARGARTGYGTNAAYATHCCNGGNAGYTAYGARTGYATHTGYTCN ACNGGNTTYGARTAYAAYTCNGAYAARGARTGYATHAARACNCCNAARGAR--------- ------------------------------------------------ATGGGNGGNACN GARAGYAARMGNMGNGTNGTNGTNGARAAYGTNAAYGGNGARGCNGTNGTNCARYTNACN GAR---GCNGCNGTNMGNMGNGTNAARGGNCAR------CCNGAYCCNGCNGTNCARAAR ACNTCNMGNGAYGAYGARMGNYTN------------------------------------ ---------AARACNATGAGYAARGARATHGARGAYTTYTAYATGGARAARYTNAAYGAY YTNCARAARAARAGYCARGCNYTNCARGAYACNACNAAYGARCARTTYTCNAAYGCNGTN AARGARGTNGARCARAARTTYATGAARTAYACNTCNTCNCCNGTNTGYCARGAYYTNCAR ACNAARGTNYTNGARTGYTAYCARACNAAYCCNAAYTCNATHYTNGAYTGYTCNTCNGTN GTNAAYGCNTTYACNACNTGYGTNGAYMGNGCNMGNATGACNGTNTCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARGCNGGNGARTGYTTYYTNCAYGGNYTNCAR GCNGCNMGNGAYTGYGGNGAYCAYAARACNGARTGGCARAAYYTNGARGCNYTNGCNAGY GTNGCNTTYCAYAARAARGCNYTNAARAARGCNGARCARCAYTAYCARCARGCNATHGCN GTNYTNTCNCARTCNCCNGARGCNGCNGAYCCNTCNGTNCAYGARMGNYTNGTNACNAAR YTNAARAGYGTNATH--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARCCNGARAGYMGNATHACNAAYCARGARGTNYTNACNAARTTYGAR AARGARAARATHYTNTAYTTYACNCCNTCNMGNMGNATHAAYGGNMGNMGNGTNGTNTGY TAYGAYGAYMGNTAYATHATHAARTAYGCNTTYGARACNGAYAGYATHGTNGTNTCNAAY GAYAAYTAYMGNGAYYTNCARAARGARAAYCCNGAYTGGAARTCNTTYATHGARCARMGN YTNYTNATGTAYTCNTTYGTNAAYGAYMGNTTYATGCCNCCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GAYGTNGCNACNATH CARYTNTCNGARGAYAAYTAYAARAGYATGGAYAAYTTYYTNGCNGAYCARATGYTNAAY AARTCNMGNGARAARACNGCNYTNMGNATHGGNGCNAARTAYGTNGTNCARGTNTCNCCN YTNGARATHGCNGAYYTNGCNCAYCCNACNGTNCARCARYTNATHCARYTNCAYCCNACN YTNACNYTNATHTTYAARMGNCARACNGTNAARTTYMGNAARAARAARGGNTTYGCNGAR GCNGCNTTYTCNACNATGACNGARYTNAARGARTTYGTNTAYAARYTNACNCARATHAAR GTNYTNGARAARMGNATHGAYGTNACNATH---------------AARACNYTNAAYGAR TCNAAYACNYTNGTNATHAAYYTNAGYMGNAAYGGNAARYTNYTNGAYYTNYTNAGYACN GGNGARGAYCCNYTNATHAAYAARCCNATGCCNATHGGNGARAARAARATHCARTTYGAR ------AARGTNCCNACNAGYACNAGYGGNGCNTTYATGCAYAGYATGTTYCCNTTYACN AAYAAYGTNYTNATHACNMGNACNTCNGTNGGNAARGAYCCNAARACNGTNTAYCAYGGN CCNGTNTCNGTNTAYTAYGTNAAYACNAARTGGYTNGARGCNGTNATGGAYTGYTGYTCN GAYTTYATGGTNAAYGAYTTYCCNYTNACNGTNCCNGAYATGAGYTCN------------ ------------------------------------------------------------ GARTCNAAYCARGGNGARYTNTCNATGGAY------------------GTNGAYGAYGAY GAYGCNGTNTCNAAYATGACNMGNGAYGTNTGYGCNGAYATGYTNGARTCNATHCARAAR YTNMGNGARYTNGARCCNAAYAAYCCNAAYATGAARAARATHYTNGAYATGCARAAYCAR ATGACNGCNYTNCARAGYTCNYTNGARAARTCN------------------CARTCNAAY ACNAGYAARGCNGAYACNAARTAYGGNTCNGAYGARTCNGGNMGNATHYTNYTNACNTCN ---------------------GCNAARAARAARGARMGNGARATGAARTAYYTNGARGAR AARYTNGARGARGCNAAYAARGCNGARYTNCARAARGARGARCARMGNAARCARCARMGN GARGCNGARYTNCARMGNMGNAARGARTTYGARCARMGNAARAARTCNCARTGGGCNAAR AAYATHYTNTCNGAYTTYAARCARGAYGGN------------GTNGTNGGNAARAARATH AGYGCNGAYGCNGARAARATHYTNMGNCARMGNGARCARMGNYTNAARGARGARGARGGN GAYAARGARAARGCNGCNGARATHCAYGGNCARGARGARGARAARAAYYTNMGNGTNMGN CARAARGARGARGARAARMGNAARGARGARGARMGNMGNMGNTGGATHGARAARATHGAR GARACNMGNCARMGN---------------------GAYTCNCARAARTTYTCNTCNTCN CARYTNYTNTGGAAYCCNTCNTCNAGYAARGTNTCNCCNTCNGCNTCNTCNACNTCNGGN MGNTCNGCNGAYMGNCAYCCNTCNAAYMGNGAYACNYTNGARGAYGGNYTNYTNYTNTCN GARGARGARTAYAGYAAYYTNGTNGCNAAYAAYCARYTN--------------------- ---CAYACNATHCCNGARGGNAGYYTNAARGTNMGNGTNGCNAGYTAYCCNAAYMGNGTN TGYCCNGTNCAYAGYTGYCCNTCNAARACNTTYTTYMGNGAYTTYAARTCNTTYYTNGAY CAYTGGATHATHTTYCAYAARGCNCARAGYACNATGAARTTYTGYCCNATGTGYTCNGCN TAYTTYATGAAYCCNGAYGARYTNGARAGYCAYATHATGAARCAYCAYMGNYTN---TCN YTNAARGARGCNAAYAAYTTYACNYTNAAYGCNMGNGTNAARATHATHGCNAAYCCNAGY TAYMGNGAYCCNTAYCCNTTY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYMGN GTNYTNTGGATGTGGCAYGARGCNMGNMGNCARGARAARAARATHMGNGGNYTNATGGTN GAYYTNAARMGNMGNGCNGAYMGNMGNMGNGARTTYTAYGARAARATHAARCARGAYCCN ACNCARTTYYTNMGNATGTAYGGNMGNCCNGTNAARATHCAYYTNGAYCCNGCNGTNGCN ATGGCNGCNGARGGNCCNCARAGYATGATGGCNTGGCARGGNGAYAAYACNAAYATGATH GAYMGNTTYGAYGTNMGNGCNAAYYTNGAYTTYATHACNGARTAYAAYCCNAARAARTCN TCNAGYACNACNATHGTNCAYGARCARGAR---GARMGNYTNGCNAAYTAYGARMGNTAY MGNACNYTNGTNGARAAYGARGCNTCNGGNYTNTCNGARGARCARTCNYTNCAYCARYTN TAYYTNGAYGARCAYTTYGGNACNATHAAYAARCCNAAYGARGARGARAARAARAARAAY GCNGAYAARAARGCNGCNATHGGNTAYGTNTAYGARGAYAGYACNCCNATGGARAARAAY GARCCNACNGARGARAGYGARGARGARAGYGARGAYGAYYTNGAYATGGCNGAYYTNGAY GTNACNATHGAYGTNGAYACNYTNACNCCNGAYATGTGYAGYGCNGTNAAYGGNATHGCN GGNCARTAYGGNATGATGGAYGAYGAYTTYGTNMGNYTNYTNMGNAARGAYAARGARGAR YTNGARGCNYTNAARGARGCNMGNCARYTNGARGARGCNAARGCNCARTTYTCNGGNMGN AARTCNMGNMGNGARMGNMGNGCNATHAAYGARAARMGNCARAAYCCNCARMGNTTYTGY MGNCCNAGYTAYGCNGCNMGNGAYAGYCCNAARTAYGARCCNTAYAARMGNCCNGGNTCN TCNTCNMGNTCNMGNTCNMGNTCNMGNTCNMGNTCNTCNGARMGNGCNGARGTNAARTTY ATHACNAGYTTYGGNGGNAAYGAYAGYGAYGAYGAYGGNGGNGGNGTNGTNCARGGNCCN TCNYTNCCNACNGCNGCNACNACNACNGTNCCNTCNAAYAARAARAARAAYTCNGARTCN TCNAARTGYGARACNCCNTGGYTNTCNTCN------------------------TCNCCN CCNMGNAGYGAYTCNAARCARGAYAGYCAYAGYTCNMGNMGNMGNCARAGYAGYAARTCN TCNACNAGYMGNTCNMGNTCNMGNTCNMGNTCNATGTCNTAYMGNMGNMGNMGNTCNMGN ------GGNAGYTCNAGYAGYMGNMGNCAYTCNTCNAGYTCNTCNTCNMGNTCNMGNAGY MGNTCNMGNTCNYTNTCNGCNAARMGNGARTCNAARMGNGTNGARAARYTNCCNGTNAAR MGNTAYMGNMGNGARAGYYTNTCNTCNAGYTCNGGNYTNAGYGGNYTNGARTCNGARGAY GAYAAY---ACNTCNYTNTCNTCNACNTCNAARAAYAARACNGGNGARGAYAARAARACN AAYATGAARACNGGNGGNAARYTNAGYAGYAARAGYTAYTCNCARAGYGTNMGNGARACN CCNCARGARMGNYTNAARMGNMGNATGCARGCNCARYTNAAYAARCARTAYAARGCNGAY AARAARGCNGARATHAGYMGNATHACNAARCARGARCARGARMGNATGGAYMGNGARGAR GARATHMGNACNYTNGCNATHGARATGMGNMGNMGNGARMGNGARMGNMGNCAYAARGAR MGNGARGARGARGARAAYAAYMGNMGNGCNAARMGNMGNGAYMGNCAYCAYAGYTCNAGY AGYAAYAGYAGYTCNMGNGAYAGYTCNMGNTCNMGNTCNCCNAGYAARAGYAGYAGYCCN TCNCCNCCNCCNAARGCNMGNMGNAARAGYCCNGAYTCNGAYGAYMGNMGNTGYGAYAGY GCNGGNGGNMGNGGNTAYAARGAYGAYAAYGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARTTYCCNTCN GTNGGNGARCARGGNMGNGAYTGYAAYCCN---------GARGARACNGARAARYTNMGN AGYGARYTNTCNGARYTNCARTCNAARTAYAGYGARYTNGARGCNACNYTNGARCARCAR CARGGNAARYTNAAYATGAGYAARCARMGNCARAARGAYTGGGARCAYTCNGTNTGYMGN CAR---GTNATGAARAGYAARMGNTCNMGNAGYYTNTCNGARTCNTTYGAYGAYYTNAAY GTNATGGARAARGAR---------------GAYMGNGAR------------YTN------ ------ACNGAYGARGAYCAYGARAARATHYTNCARATHAAYAAYACNAARATHYTNAAY CCNGARMGNMGNCCNCARTAYGARCARATHAARMGNGCNTAYGCNGAYATHYTNTAYAAR TGGGGNYTNYTNAAYCARMGNGCNCARGTNYTNAARCAYACNGTNTCNGTN---CARAGY AGYCARAARATHGARTTYTCNATHCCNTGYTCNAAYTGYTCNGAYACNGTNATGAGYGTN CARTGYAAYMGNTGYMGNTAYCCNTCNYTNAAYTGYGCNATHTGYCAYATHGGNGTNMGN GGNACNGCNAAYGTNTGYCARACNTGYGGNCAYGGNGGNCAYGCNAGYCAYATGATGAAR TGGTTYCAYAGYAAYACNYTNTGYCCNAGYGGNTGYGGNTGYCARTGYYTNCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GCNGARYTNAAY CARCARYTNMGNATHAAYMGNGARCARATGCARAARCARCAYGAYGAYYTNGTNCARTGY MGNCARGCNYTNAGYTGYGCNCARMGNGAYGCNGAYAARYTNMGNMGNGARYTNGAYGAY GCNATHGCNAGYYTNGARCAYMGNGARTGYGARATHACNMGNYTNAAYGARGARMGNAAR ATHYTNATGGARAARGTNGCNTCNYTNACNTGYCAYYTNGAYCARGARACNGGNATGYTN MGNCARCARATGGCNGARACNAARTGYMGNYTNGARAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GGNTAYGGNGGNTCNGGNGGNAGYTAY GGNACNGGNAGYTAYGGNGGNTAYGAYGGNGGNTAYGGNACNGGNGGNGGNYTNGGNAGY GGN---AGYCAYGGNTAYGGNGGNAGYGGNTAYGGNTAYGGNGGNAGYGCNYTNGGNGGN GGNGCNAAYATHGGNGGNGGNCAYAARGGNGTNCAYYTNCCNAGYMGNGTNAGYTAYAGY CAYGGNTAYACNAARTCNCCNYTNATHTCNTTYGTNAARGGNTTYAARCCNGGNAARATH TAYGTNGAYAARGGNCAYGTNATHMGNAAYTAYTTYMGNCAYGGNACNTAYAAYGTNGCN YTNCARCAYTAYAARYTNATHCCNACNGTNAARATHGTNCCNTAYACNACNTAYAARAAR ATHGGNGTNGGNCARAARGTNCARGCNAARTAYCARTAYAARGCNGTNATHTGYAARTAY TGYTAYCAYGGNTAYCCNAARATHGAYGTNTAYGARATGAARAARCCNTAYAGYTAYGCN GTNAARMGNTTYGTNTAYYTNCCNAAYGAYTAYAAYYTNGGNGGNGARGGNTAYGGNAGY GGNTAYGGNAGYGGNTAYGGNAGYGGNTAYGGNAGYGGNTAYGGNAGYGGNTAYGGN--- ------------------------------------------------------------ ------------------------------GARACNATGGCNYTNACNAAYGAYAAYACN GCNYTNGCNGTNGTNYTNTAYAARGARGAYAAYYTNYTNCCNCAYGARAARAARAGYMGN AAYTTYCAYATHGCNGGNCAYGARTAYCAYATHGARCARAAYTGGCAYGTNGGNGGNGTN GCNGCNGTNGTNTGGGAYGCNGCNYTNGTNYTNGGNGARTAYYTNGCNTCNAGYCCNCAY YTNGTNAARGAYAARAARGTNYTNGARYTNGGNGCNGGNACNGGNYTNGCNGGNATGGTN GCNTCNTCNYTNGGNGCNGAYGTNATHGTNACNGARMGNGARGARGCNATGCCNTTYYTN GARAGYACNYTNTCNGCNAAYAARATHGAYAARAAYTGGAARATHAARGCNGAYGTNYTN GAYTGGACNCAYCARATHAAYGCNTCNAAR------TGGGAYCARTTYGAYYTNGTNATH GGNGCNGAYATHATHTAYATHGARAGYACNTTYTCNTTYYTNYTNAARACNATHAARTCN GTNGCNGCNTCNCCNAARACNCAYATHYTNYTNTCNTGYMGNATHMGNTAYGAYMGNGAY YTNMGNTTYYTNCAYATGYTNAARAARTTYTAYACNATHGARGARATHTAYTAYGAYTCN AARYTNGAYATHAARATHTTYTCNGCNATHTCNAAR------GTNGTNCAYYTNGGNGGN TGYCAYTGYGGNGCNGTNMGNTTYTCNGTNAARGCNCCNGCNCARYTNAAYGTNGTNGAR TGYAAYTGYAGYATHTGYTGYAARAARCARAAYAGYCAYTTYATHGTNCCNAARGCNMGN TTYACNYTNYTNCARGGNTCNGAYCAYATHACNACNTAYACNTTYAAYACNCAYCARGCN AARCAYACNTTYTGYAARACNTGYGGNGTNCARAGYTTYTAYACNCCNMGNTCNAAYCCN GAYGGNTAYGGNATHATGCCNCAYTGYYTNGAYCCNGGNACNATHGARTCNATHAARGTN TCNACNTTYGAYGGNAGYAARTGGGARGARTCNATHAARGAYTCNAARATHMGNCARTAY TCNAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GARGAYYTNTCN------CARMGNACNGAR GARTCNGCNGGNCCNTCNCARGGNTCNCARGGNCARYTNACNGARTCNYTNTCNGCNMGN CARMGNTCNYTNATHAAYATHGTNTCNAARGARCARAARAARTGGAARGGNACNGTNCAR GARCARMGNMGNAAYATHTAYGAYMGNCAYTCNATGYTNAAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AAYCCNAAYCCNGGNGARAAYGAYACNACNGGNYTNGARGGNGCNGGNAARMGNTGG GCNGCNTTYAAYGGNGGNGTNGGNGARAARCARYTNCAYTGGYTNTCNCARACNYTNGAR AARGCNCARTCNAARCARGARAAYGTNATHATHTCNTCNCAYATHGGNTTYTAYCCNAAY ATHCCNGARAAYTAYTCNYTNTCN------TGGACNTAYGARGARGTNYTNGARGTNGTN CAYMGNTAYGARTGYGTNATHGGNATHTTYGCNGGNCAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CARYTNGTNAARGTNYTNAAYGGN YTNGTNAARAARTTYGARGCNAAYGGNATHTCNGAYCCNTCNTCNAGYGCNGARTAYATH ACNGCNCAYATHYTNGGNAARAARACNYTNTAYGGNGTNGAY---GCNAAYGARTGYATH AAYGAYTCNGAYGTNGCNGCNATHAAYAAYYTNTGYGARATGMGNYTNAARMGNATGCCN GTNCARTAYATHYTNGGNCARTGGGAYTTYGAYGGNATGACNYTNGARATGAARCCNCCN GTNTTYATHCCNMGNCCNGARACNGARGARYTNGTNGGNCAYTGYCARGAYATHYTNGAR TCNAAY------CCNTCNYTNTGGCARACNMGNCCNGTNACNYTNGARYTNGGNTGYGGN AGYGGNGCNATHAGYYTNGCNYTNYTNAARMGNTTYAARGGNYTNGARTCNGTNTGYGTN GAYGTNYTNCCNGARGCNTGYGAYYTNACNAARMGNAAYGCNAGYATHGTNGGNGTNGAR GAYMGNATHMGNGTNATHAAYGGNGAYTTYACNTGYMGNAARGTNATHTCNTGYYTNCAY TCNYTNGGNCCNTTYTGYYTNYTNGTNAGYAAYCCNCCNTAYGTNACNYTNGAYGARATG GARGARYTNTCNCCNGARATHGARMGNTTYGARAGYCCNGTNGCNYTNAAYGGNGGNGTN GAYGGNYTNGAYATHGTNMGNCAYATHYTNAAYCARGCNGARAARTTYYTNATGYTNGAY GGNCAYATHYTNYTNGARGTNGGNGARAAYCAYCCNGCNATGATHAARAAYATHGTNACN AARAAYAAYACNAAYATHMGNYTNCARTTYATHACNGGNGGNAARGAYATHTAYAAYMGN GAYMGNTTYTGYCAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GTNGARGAR AGYCARATHGARGGNAARYTNCAYGTNACNGCNACNGAYGARAAYAARGTNGTNATGAAY ATHTCNMGNCAYGGNATHAARGTNTTYGAYATHGCNGGNAARGARGTNYTNCARMGNCAY CCNYTNCAYACNATHGCNCARYTNACNCARTAYAAYGAYGGNTTYGGNMGNCARAAYATH GCNGTNAARATHGGNCARGTNGGNAARAAYGTNTAYCARTGYTAYGTNTTYCARTGYCAY TCNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYATHGCNTAYACNGGNYTNGTNATHGTNGTN GCNGTNATHYTNATGTTYTAYGTNGCNCCNAARTAYGGNACNACNAAYATHYTNGTNTAY GTNTCNATHTGYTCNYTNATHGGNTCNYTNACNGTNATGGCNTGYAARGGNATHGGNATH GCNYTNAARCARACNATHGCNGGNGTNAAYCARGTNACNAAYCCNGTNACNTGGATGYTN YTNATHGGNGGNGCNATHTGYATHATGATHCARATGAAYTAYYTNAAYAARGCNYTNGAY ATHTTYAAYACNTCNATGGTNACNCCNATHTAYTAYGTNATGTTYACNACNTGYACNATH YTNGCNTCNGCNATHYTNTAYAARGARTGGTCNMGNYTNGAYGCNAARGAYACNYTNGGN TCNATHTGYGGNTTYYTNACNATHATHTGYGGNGTNTTYYTNYTNCAYTCNTTYMGNGAY ATHAARACNACNYTNYTNGAYYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYMGNATHACNYTNGAYMGNMGNGARAARCARATHGGNTAYGGNAARMGNACN GARTCNTAYCARYTNTAYATHAARTCNGTNCCNAARGAYCARMGNGCNYTNGAYMGNMGN MGNCAYCCNCARACNCCNGAYAARAAYATGMGNYTNAGYMGNMGNAAYTTYGAYGCNCAR ATHAARGCNTGGAARAARCAYGTNCAYCARTGGGCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------MGNAGYAGYMGNMGNTCNTAYACNTCNTCNGARTAYACNTCNMGNTCNTAY TCNMGNTCNMGN------TCNGGNTCNTAYMGNAGYTAYTCNGAYGAYTCNMGNTAYAGY GAYTCNAGYMGNTCNCAYAGYMGNTCNTCNMGNAGYTAYAGYMGNAGYCAYTCNMGNCAY MGNTAYMGNMGNMGNTCNTCNTCNAGYMGNGGNMGNAGYMGNAGYTAYAGYTAYAGYAGY MGNAGYAGYTCNAGYMGNTTYMGNTCNMGNTCNTAYTCNMGNTCNMGNAGYTAYACNMGN TCNMGNTCNMGNGGNMGNGGNTAYAARAGYAGY---TCNMGNAGYCCN---MGNMGNGGN AGYGTNAARYTNAARMGNATHYTNAARTCNCCNYTNGCNATHGTNCCNGTNACNACNYTN ACNGTNGCNCCNGTNACNGGNTGYACNATHGGN--------------------------- ------GGNGGNGGNAARGGNAGYGGNGGNGCNGCNCCNGAYGAYATHCCNYTNCCNGGN AARGAYTCNYTNGCNACNTCNACNAGYCCNAARAARGAY---------GARGAYAARTCN GTNYTNACNGAYATHCCNYTNCCNACNTCNACNAGYAARGGNCCNTCNGAYGGNAARGAR AAYTGYAAYTCNGARAAYGCNCCNGTNATHAAYACNAGYAAYGGNGARTCNGTNAAYACN GCNACNGTNCCNCCNGAY---------CCNGAYYTNCARGCNAAYCCNACNAAYGGNGGN GGNGGNGAYAGYCAYGTNGGNGGN------GARAAYAAYYTNYTNCCNGARGARYTNGGN GGNGGNGGNGGNATGGGNAAYCCNGAYATGATGGGN------------------------ ---TAYAAYCARGAYTCNTAYAAYCARATGGGNTAYGGNACNCAYGAYGCNGCNTTYTGY GARGAYACNGGNTAYGAYAAYTTYGAYTTYGAYGGNGCNGGNGARTAYGAYCAR------ ---GGNTAYGAYGAYGARCAYCAYGAYTAYGAYTAYAAYCCNGAYCCNTAYCAYCAYCCN CCNYTNMGNCAYCARGGNCCNCCNCAYGGNCAYCAYATGMGNGGNCCNCCNCCNCCNGGN TAYMGNGGNCCNCAYCCNMGNATHTTYCCNCCNGAYATGMGNTTYGGNCCNCCNMGNCCN GGNATGGGNCCNCCNMGNATGMGNCCNCCNAAYGGNCCNATGGGNCCNCAYCAYCCNATG GGNCCNMGNGGNCCNMGNCCNCCNMGNGGNCCNGGNGGNCCNATGGGNCCNCCNGGNATG MGNGGNCCNCCNCCNMGNGGNCCNCCNCCNMGNGGNCCNCCNGGNATGMGNGGNCCNCCN GGNATGCCNGGNCCNMGNGGNCCNCCNCCNMGNCCNGGNATGATGGGNCCNGGN------ GGNCCNATGGGNCCNAAYGGNCCNMGNCCNMGNATGGGN---CCNCCNACNMGNATGGGN CCNCCNCCNCCNGGNCARGGN------------GGNCCNCCNCCNGGNGGNCCNMGNAAY MGNATGCCNCCNCCNGGNCAYATGCARGGNCCNCCNATGMGNGGNGAR------GGNCCN CCNMGNCCNGGNATGCCNCAYCARGGNMGNGGNCCNATGCCNCCNCAYATGMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNGARTGGGCNATGGARAAYGTNCCNACNGCN TTYCCNAGYAAYGTNTTYCARTGYYTNATHGARATGGTNCAYGTNCCNGARGGNGTNGCN AAYTAYGARGARGCNYTNCARAAYGCNGARGARGARTAYATHMGNACNTTYTAYGTNMGN AAYYTNAARYTNGCNAARACNAGYGARGAYCAYCARYTNMGNCARGAYYTNYTNAARAAR ACNATGTCNCAYATHYTNGGNAARGARGAYATGGARGGNATHTGYCARGCNTTYGGNYTN AAYAARAARGAYATHGGNAAYYTNAGYMGNAARTTYGGNTCNGARAAYGCNYTNAARACN GGNYTNYTNGAYGARTGYTCNAARATGGGNYTNMGNGARYTNTGGAGYATHYTNCARGAY GTNAARGARGAYAARACNYTNGCNGAYTTYMGNGGNAARAARYTNGCNGTNGAYTTYAGY GGNTGGYTNATHCCNATHACNGCNGCNGCN---AAYTTYTCNTCNMGNGCNATGTTYTTY MGNATHYTNGAYYTNATGTCNCAYGGNATHACNCCNGTNTTYGTNTTYGAYAGYGCNAAR GCNATHGCNATHAARGARMGNAARMGNGGNGTNGARTAYTTYMGNTCNACNCARCARTGG GARGARYTNYTNAARGCNATGGGNTTYCCNGTNATGMGNGCNGARGGNGARGCNGARAAR ACNTGYGCNYTNYTNAAYGCNTCNAARATHGTNCAYGGNGTNATHACNAAYGAYGGNGAY GGNTTYGCNTAYGGNGCNACNAARGTNYTNAARGAYTAYGCNACNAAYATHACNAARAAR AARATGATHCAYGTNTAYGAYTCNTCNAAYYTNAARACNAGYAARGGNTTYGGNCARATH GARATHATHGTNGCNGCNATHYTNATHGGNTGYGAYTAYTAYAARGGNGTNCCNAARGTN GGNAARGARATGTTYCARAARYTNYTNGARGARTGGGAYGGNAAYGGNGTNACNGAYGTN YTNGGNMGNATHMGNACNTGGAARACNAAYCCNGGNYTNYTNTCNYTNGTNGARGAYATG AARAARATHAGYATGATGMGNAARAAYCCNCAYTGYTCNCARTGYGGNCAYYTNGGNACN ATHMGNCARCAYGARAAYGAYGGNTGYGGNACNGCNTCN--------------------- ------------------------------------AGYCCNTGYCCNTGYGARTAYCAY ACNYTNAARGAYMGNATHAARCARTGYTAYGTNGARYTNGARGTNMGNGARAARGCNYTN GCNYTNCCNAAYTTYCCNCCNGARGAYGTNATHTCNGARTTYYTNATGCARGAYGARGCN TTYGAYTAYGAYATHGARTTYAARGTNAARAARACNGAYTAYACNMGNGTNTTYGARATG YTNAARGARCARYTNGARYTNGGNAAYGAYGAYATHAARAARTTYTTYCCNGCNYTNGTN AARATGATHYTNTAYGGNCARGARACNGAYTTYGARGTNYTNCCNGTNGGNAAYYTNAAR GARTGYAARTGGAARGGNGARYTNTGYTAYGARGTNAARTTYCARMGNTTYGGNTTYGAY ACNATHCARGAYGARACNGGNTAYGAYATHAARGTNGTNMGNAAYGTNGTNGARTCNMGN TTYCCNGAYYTN------------------------------------------------ ------------------------------------------------------------ ---------------------GTNAARAAYAAYGTNTGYGARAAYCAYTTYCARATGGCN AARAGYAGYYTNGARMGNCARMGNACNAGYAARYTNAARCARYTNCAYGAYCAYGCNAAY MGNYTNMGNCAYGARGTNAARYTNYTNGAYYTNGAYMGNCARMGNCAYACNGTNGARGTN MGNAARMGNYTNGARCCNGARAARGAYTAYAGYTAYGAYGARGTNCARATHCAYAAYACN GARAARMGNYTNGGNGCNAAYATHGCNTCNTTYTAYYTNGAYAARAARYTNAARTAYCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGGAR GCNAGYAARATHTCNMGNYTNMGNGAYGARCARCARAARGCNATHTCNGARACNGARGAR AARATHACNCARTTYGARMGNTAYAARGCNGAYTAYAARGCNYTNCARAARMGNYTNGAR ACNYTNCCNGAYAARGTNACNCAYGAYGTNATGGTNCCNTTYGGNAARAARGCNTTYATG CCNGGNCARYTNGTNCAYACNAAYGARATHYTNGTNYTNYTNGGNGAYAAYTGGTTYGTN GARMGNTCNGCNAARCARGCNTGYGAYATHACNGAYMGNMGNATHAARGARYTNGAYACN MGNATHACNGARYTNAARAARCARAARAGYYTNYTNGTNCCNMGNYTNGGNATGACNTCN GARYTNCARGARGTNGCNGARGGNYTNGGNGAYTAYMGNGARATHATHGARGARTAYGAY GARGARAARGARMGNCARTGGGAYGARCARCAYMGNATHAAYGTNMGNMGNCAYAARATH CARGARCARMGNAARACNAARGAYAGYGARMGNAARGARATGAARAGYGTNACNGCNTCN MGNAAYMGNAGYGAYGARGAYYTNTGGTCNMGNYTNGAYGAYYTNGARAARCARGARGAR GARMGNGGNGARYTNAAYAGYAGYGARGARCARMGNGAYCARGARAARAAYGGNGAYTCN GARAARAARATHGTNTCNCCNACNGGNGAYMGNMGNGTNAAYTGGATHGAYGAR------ ------------------------------GARMGNGTNMGNAARGAYAAYGARGAYAGY GGNGGNGAYAGYGAYGAYGAYGAYGAYAAYGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TCNYTNGARGAYGTNGTNATHGGNTAYCAYGARGAYGAYYTNTCN TTYGTNAARAARYTNGCNGAYAARYTNMGNTCNGCNGGNYTNAGYGTNTGGTAYAARAAY CCNMGNGAYGAYGCNACNAARATHAGYGARGCNATHYTNGGNTGYAARGTNTAYYTNCCN GTNYTNACNGAYYTNTCNGCNGTNGAYAARGGNATHCAYGARCARYTNTCNYTNGCNTAY ATHTCNAAYTCNGCNATHTAYCCNYTNGGNAARATHMGNTTYAAYYTNYTNGCNCCNAAR YTNAAYGGNGGNGCNMGNYTNATGYTNGCNAARATHAAYTGGTCNTTYATHYTNAARGAY GARCAYTTYGARCCNMGNACNGAYACNATHATHGARTGYATHAARAARGAYATHGCNAAY ATHGARAARACNTTYGAYTCNCCNGGNGAYGGNTCNGGNTAYGTNGTNACNCAYGGNATG CARATHCCNGTNAGYACNACNCAYYTNCARAARACNGGNGAYCARGARCCNGARTTYGTN GCNTTYTCNCARGGNATHGAYYTNAGYTCNATHAGYCARGAYACNCCNTTYTGGGAYMGN CAYTTYAARGGNAARAARGARGTNACNTGGATHGARTAYMGNGAYAARTTYYTNCARGAY TAYGGNGCNAARATHATGGARGGNTTYTCNGARAAYGCNGAYGARMGNAARAARYTNTTY GTNAAYYTNATGTAYAARGAYGTNTTYGCNYTNAGYAARATHGTNAARMGNTCNGTNTAY GAYAARTTYTGYGGNAARCCNCAYCCNCAYGCNTTYTTYACNGGNATGCARGAYTAYGTN ATGGCNTAYGCNTCNYTNMGNGARGTNYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHGAR GAYATHGARAARATGATHGARMGNTGYGARAARAARATHGAYGARYTNGARMGNAARGAY MGNYTNGTNGARATGTCNGAYGARCARTGGGARGAYYTNMGNAGYGARAARAARTCNYTN GARAARCARATHAARAARTAYAARAGYGARYTNMGNAGYYTNMGNTGGCARAAYTGGAAR AGYATGGTNATGTCNYTNTTYATHTTYGGNYTNYTNTAYYTNGGNTAYATHATGGTNTTY GAYTCN---------------------------ATGGAYACNTGYGTNCCNAGYCCNAAY YTNYTNAGYACNCCNTTYGCNCARAGYCCNCAY--------------------------- ------------ATGTAYTGYGARAAYTCN---AAYGTNAAYTAYAAYTCNGAYYTNTGY GGNGCNGTNCCNGAYGARAGYGGNYTNYTNGAYGAYAARTTYGARGAYAGYACNYTN--- ACNATHTTYACNCCNGARYTNATHAAYTCNATHACNAGYACNGCNCCN------------ ---------------------------------GCNACNGGNTTYACNTCNACNGAY--- YTNTGGAAYACNAARGTNGCNATGGAYGARTCNYTNTCNCAYGAYACNGTNATGGAYGCN CCNTTYGTNCCNYTNGGNATGGAYTCNGAR------ATHTTYATHAAYYTNYTNAAYGAY TCNAAYGAYAGYMGNTTY------TCNATHCCNGAYYTNGAYYTNATGTCNAGYTAYCCN CCN------------TCNTCNTGYCAYACNCCNACNCCNGCNTCNGARCCNAARATHATG GCNTTYCCNYTNGGNCAYAARGARACNGARTCNATGATGAAYGCNAAYACNTTYGCNCCN AARAARTTYACNACNATGAARTCNAAYTTYCCNCCNMGNAARTCNGARCCNCCNGTN--- GTNGTNGCNCCNGTNAARGTNGARGARGAYCAR--------------------------- ---AAYYTNTTYAAYAAYCCNCARCCNGTNAARATGGARATHAARGARCARTTYCCNAAY ATGGARAARAARGAYGTNCARTTYACNAARATH------------AAYTCNTGYGGNGTN GAYGTNTCNGARYTNTCNCCNCARACNGTNCCNTCNTTYACNGCNTCNAARCARGARGTN GTNAGYMGNCARGTNAARTTYGARTCNAAYMGNCCNGARATGATGGCNCARCCNTAYGGN AARMGNTCNTCNACNGAYGTNAARGAYTTYATGCCNGGNGAYTTYATGACNTCNGCNAAR ------------AAYAARMGNMGNMGNTGYGAYTCNGGNAGYTCNGGNATHACNTCNGAR GAYGGNGAYGAYGARGAYAAYGAYTAYCARTAYCARATHGAYTAYGAYAGYGAYGAYGAY ---------GAYYTNGAYGCNGAYYTNGCNCAYATGAARCCNGGNGGNTGYGARTCNYTN ATHGGNGGNGGNAARAARCARAARCARTAYTTYTGGCARTAYAAYGTNCARGCNAARGGN CCNAARGGNACNMGNYTNAARYTNGCNGTNGARTCNCCNTCNGAYCCNCAYATHYTNAAY GGNTTYGARGAYCCNGTNTTYGAYGARGGNAAYACNACNGTNGCNGGNATHMGNCAYGGN GGNAARGCNMGNAARGGNGAYGGNAAYGARGTNACNCCNAAYCCNCAYAARYTNTTYAAR ATHGGNCAYCARYTNYTNMGNYTNAAYAARAARATHAAYGCNTGYCARYTNGGNTCNGAY GTNCCNYTNGCNCARMGNAAYGARTCNMGNAARGARAARAAYAARYTNGCNTCNMGNGCN TGYMGNYTNAARAARAARGCNCARCAYGARGCNAAYAARATHAARYTNAAYGGNYTNGAR ATGGARCAYGGNCARATHAAYAAYGTNYTNMGNYTNYTNTGGCCNGARYTNMGNGARMGN GCNAARCAYYTN------CARAAYGARCARAARCAYYTNGARGTNAARCCNGAYCCNGAY AAYAAYYTNTAYACNAARYTNACNGGNTAYATHAGYTCNAAYYTNAARTCNATGGTNGCN GAYAAYACNACNGAYTAYGTNAAYGAYGTNATHATGACNGTNGARAARGGNGAYYTNACN GGNGGNYTNAAYATHMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GCN CCNAARGGNCARTAYTTYMGNGAYYTNATHTCNAAYGARTCNGARMGNYTNATGAGYATG TCNCARMGNTGGAAYGAYGTNGCNACNMGNGARGTNGGNYTNCARGARGARGTNYTNGGN CARATHMGNTCNACNGTNGGNAARGCNGTNYTNYTNATGGAYCARMGNTTYAARCARTTY TCNGGNYTNGTNGAYAAYTAYGTNTTYGAYYTNGGNGARAARAARACNACNCCNACNGAY YTNCARGGNTTYTGGGAYATGATHTAYTTYCARGTNGARGAYGTNAAYAAYCARTTYAAR GARYTNGARGARYTNCARCARTCNGGNTGGCARGCNAARAGYAAYACNCCN--------- ---------AARGCNACNGGNYTNCARYTNAARAARAARATHACNAARGGNCCNAARGTN AARGGNAARTCNAAYTTYGCNGCNTTYMGNGCNGARYTNCARAARAARAARGCNCARGCN GCNTCNACNYTNCCN---GARGARYTNAARAARATGAARGTNCCNGARYTNAARCARGCN YTNAARGAYAARGGNYTNACNACNTCNGGNGCNAARTCNGAYYTNATHAARMGNYTNGTN GAYTCNACNYTNGGNGCNGCNGGNGAYAGYACNGAYCCNGTNYTNGAYGAR--------- ------GAYGARATHYTNAARGAYGAYTCNACNCCNCCN--------------------- GTNGCNGCNGTNCCNCCNCARCCNGCNCARGTNYTNTCNACNGARAARTCNGARACN--- ---------------GCNAGYAAYGGNGTNGTNCARGCNAAYCCNCARCCNACNCAR--- ------ATGGCNGCNGAYACNACNGCNATHGCNAARCCNGAYGARGTNAARAARYTNACN GARGCNGARMGNYTNAARATGMGNGCNGAYAARTTYGGNGTNACNTCNGARCARGCNAAR AARGAYYTNMGNGCNCARMGNTTYGGNATHGCNYTNAAYGARAAYAARTCNGGNAAYATH GGNTCNTCNACNGARCCNGTNGAYGTNGARAARYTNAARAARMGNGCNGARMGNTTYGGN GTN------------TCNACNAGYTCNGTNACNGARGAYGARAARAARMGNAARMGNGCN GARMGNTTYGGNACNAGYYTNACNACNTCNAGYACNTCNAARAGYATHAGYYTNAAYTCN ACNGAYAGYGARYTNGARGCNAARAARMGNAARMGNGCNGARMGNTTYGGNYTNTCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARTTYTCNTCNTTYGARAGYGGNAGYGARGGNCARAARAARGGNGTNTTYYTNGTN AAYAGYCCNYTNGARGAYGTNACNGARCARATHYTNCARGAYATHATHACNCARAGYCAY TTYCARTAYGTNGTNGTNYTNACNACNGCNCAYCCNYTNYTNCAYTCNAARATHACNGCN GCNAGYATHGARAAYGGNGCNGCNTTYGARGAYTTYGARGARCARATHYTNGARTGGATG GGNGAYATGAAYTAYACNTCNGARGTNCARCARATHAAYYTNTTYAGYTGYGARGTNTCN CCNGGNTTYTTYATHACNCCNGCNTTYTCNGARYTNTTYCCNYTNYTNCCNTCNGAYYTN CARCARATHAAYTAYCAR---CARGGNATHAARCAYACNAARGAYGCNAARAAYTGYGAR GGNYTNAAYGAYGTNGARATHACNAAYYTNCCNGARGAYYTNGARGTNGARATHMGNYTN TTYTCNACNTCNYTNGAYGGNYTNYTNCARTCNYTNAAYGTNAARGARGAYATHTAYTCN ATHGGNTGYYTNAGYMGNATHATHGCNACNGAYYTNGAYAGYTTYCCNCCNGCNAARGCN MGNMGNAARATGGCNCARGCNMGNATGTCNYTNYTNYTNATHGAYMGNAGYYTNGAYYTN GCNTCNGGNGTNACNAARCARGCNGAYGTNYTNYTNGAYAARATHTTYAAYACNYTNCCN GCNATGGGNGCNAAYCAYTGYGAYMGNYTNGTNGAYATGGCNGAYYTNTGYCAYTGYTAY AAYACNAARTCNAGYCARCCNYTNATHYTNCCNGGNTGYYTNGCNCCNACNTCNGTNCAR GAYTCNGTNACNCAYYTNACNCCNACNGTNATGAARAARCAYAARGARGTNYTNATGGAY ATHAAYMGNCARYTNGTNGARATGGCNGCNTCNGARAARYTNCCNYTNGAYYTNTCNMGN MGNCCNAGYMGNGTNACNCCNGAYYTNYTNGAYTCNACNYTNGCNYTNTTYAARGGNAAR TAYGAYYTNATHCAYAARCAYYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNTCNGAYYTNGCNCAR AAYAARYTNCCNAARGTNGARGTNGARGARGAYCARGTNCCNYTNGTNMGNTTYYTNTGY GGNGCNGAYYTNYTNGARTCNTTYGCNGTNCCNGGNYTNTGGAARGAYGARGAYATHGAR AAYATHGTNAARAAYCAYGGNYTNGTNGTNATHAAYMGNGARGGNTCNAAYGCNGAYAAR TTYATHTAYGARTCNGAYGTNYTNACNAARTAYMGNGARAAYATHGTNYTNGTNAAYGAR TGGYTNAGYYTNGAYATHAGYTCNACNAARATHMGNMGNGCNTGYMGNMGNGGNGARAGY YTNAARTAYGTNGTNCARGAYACNGTNATHGAYTAYATHMGNGARCAYMGNYTNTAYGGN YTNCCNGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GCNYTNCARAARYTNGTNGTNGTNYTNAARCARTGY TGYGAYTCNYTNCAYMGNTCNMGNYTNYTNTGYYTNTTYGCNGAYTGYTAYTTYAAYATG GGNTGYCCNCARYTNTCNATHCARACNTAYMGNGAYGCNYTNCAYGCNGAYGCNAGYCAY TAYTCNATHYTNTAYCARYTNTCNYTNGTNTAYCARAGYATGGAYYTNCCNGAYYTNGAR YTNGARTCNYTNAAYYTNTGYGTNATGGCNYTNGCNGAYTCNGARMGNAARAARACNGAY MGNGTNCCNATHATGACN---YTNGAYGARGTNGTNTGGTCNATHGTNCCNCCNGTNACN CARATHTCNTAYATHATGGCNAARGTNACNTTYGCNAARMGNTGYATHCAYYTNAARMGN TAYCCNGARGCNGCNGARCARTAYTCNAGYYTNATHAARATGYTNCARCARGCNGAYACN TTYYTNCARTTYGARAARCAYGARATGAAYTGGACNYTNAAYATHGCNGARATHYTNGTN GARGCNGCNGARGTNYTNYTNATHGCNMGNCARTTYCARGARTGYATHMGNYTNTGYGAY AAYACNCARCCNTCNYTNTCNGCNGAYGAYACNTTYGCNMGNAAYMGNCARGCNACNGCN GARCAY---------------CCNACNAAYGCNATH------------------ACNTCN YTNAAYTCNCARTCNGAYATHTTYGAYYTNYTNAAYAGYTCNCARAAYGARGAYGCNGCN AAYACNYTN------------YTNAGYCCNMGNAARAARCCNGCNACNCARAAYCARAGY CAYTAYGARACNGCNGCNACNGAYYTNTCNGTNTCNTTYGARAARTCNMGNAARMGNATH MGNTCNAGYGGN------------------CCNATGACNAARGAYGGNATGAAYAARACN TTYAGYGAYAGYAAYGAYTTYYTNYTNGCNMGNYTNYTNYTNTGYAARGCNGAYGCNYTN GTNATGTCNCARGGNATHACNGAYAAYGCNGTNCAYTGYYTNCARCARTCNATHGAYATH YTNYTNGAYACNTCNGAYAARYTNCCNGGNGGNGARCCNACNATHCAYCCNCCNCAYTCN AARMGNYTNMGNATHAGYTCNGAY---------------GGNAARGCNGTNTGYCCNCAR CARGGNGAYGCNGAYGCNTCNAAYGTN---TGGTCNAARYTNYTNGTNGCNACNGCNYTN MGNATGGCNGCNGCNTCNTGGAARMGNGCNMGNTTYTCNTCNGTNATHAAYAGYTGYCAR GTNGTNGARCARYTNGAYMGNGGNAAYATGGAYGTNGTNTAYYTNTGYGTNGARGARCAY YTNGGNGCNGGNATHCAYCARCAYCCNACNGAYTGYAGYAARTTYATHGARTGYACNCAY GGNGTNGCNTAYGARATGTAYTGYCCNGCNACNYTNGCNTTYAAYCCNGCNATHAARGCN TGYGAYAGYACNGCNAAY------------CCNAARGGNACNAAYGCNCCNACNACNACN TTYGAYCAYYTNTGYGARAAYAAYGCNTGGATGTCNGGNACNCAYCCNCAYCCNACNGAR TGYCAYAARTTYATHGARTGYGTNGGNGGNMGNGGNGTNGARATGGTNTGYCCNGTNGAY YTNGCNTAYAAYCCNGAYAARYTNTAYTGYGAYCCNATHAARATGGGNTGYACNAARTAY ATHACNGARGGNCCNGGNYTNACNGTNGCNCCNGGNGTNTCNTTYYTNCAYTTYTGYGAY GAYCAYAARTTYTCNGAYTCNYTNCAYCCNCAYCCNACNGAYTGYCAYMGNTAYATHGAR TGYTCNAAYGGNYTNGCNTAYGTNATGACNTGYGCNGCNGARYTNGCNTTYAAYGAYGCN ATHGAYTCNTGYGAYAAYGCNAAYACNYTNAAYTGYAAYACNGCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNGGNYTNTCNGTNTTYYTNGARACN GAYGCNACNGAYYTNCAYAAYCAYCCNGTNATHAGYAARGARAGYTTYGAYCAYATHATH TTYAAYTTYCCNYTNGCNGAYMGNCAYAAYATHAARAARAAYMGNTCNYTNYTNGCNGAR TTYTTYTCNAGYTGYMGNTCNGTNYTNGCNCCNGARGGNTGYGTNATGGTNACNYTNTGY AARGGNCARGGNGGNACNCCNGCNGAYAAYCCNATHMGNTCNTGGCAYGAYAGYTGGCAR GTNGTNGCNATGGCNACNAAYGCNAGYTTYYTNYTNAGYGARGTNYTNCCNTTYCAYCCN GCNGAYTTYCCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNAGYATHATHGGNATGATHGTNGGNYTNTCN GCNGGNGCNGTNTTYAGYTTYCAYTTYAARAAYTAYAAYGCNGGNYTNTGGGGNYTNTGY TCNGCNATHGCNGCNTTYACNGCNYTNTGYGTNACNGTNGCNTTYATHMGNMGNGCNTGG GAYTCNAAYCCNYTNGCNYTNAAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGAGYGCNTCNGAYCCN ACNTCNTAYTCNGARCCNGARAARTGYGARATGAARAARYTNAAYTGGAAYGTNAARYTN GAYTTYGARAAYCARACNATHAGYGGNGTNGCNAGYYTNTAYTTYGARAARAARAGYGAY AARYTNGAYYTNYTNYTNYTNGAYGTNMGNGAYYTNAARATHGTNAGYGTNCAYYTNCAR GARAAYAAYCARACNYTNAGYTTYACNATHGAYAAYCCNTCNAAYGTNAAYTAYGGNTCN MGNYTNTGYATHCARYTNCCNYTNATHGCNAGYAAYAGYTTYACNATHGAYGTNACNTAY AGYACNTCNAARAAYTCNACNGCNYTNTGYTGGATGMGNCCNGARCARACNGCNGGNAAR MGNCARCCNTAYYTNTAYAGYCARTGYCARGCNATHCAYGCNMGNAGYYTNTAYCCNTGY CARGAYACNCCNGCNGTNAARTTYGCNTAYAARGCNCARGTNGARGCNCCNAGYGARATH ACNGTNYTNATGAGYGCNAAYMGNGGNGARGTNAAYCCN------GGNTCNGARGGNCAY AGYATHACNAGYTTYTCNYTNGAYATHCCNATHCCNAGYTAYYTNYTNGCNATHGTNGCN GGNGAYYTNGARTCNMGNGAYATHGGNCCNMGNTCNAARGTNTGGTCNGARAARGARTTY GTNGAYMGNGCNGCNTAYGARTTYGGNGARACNGARTCNATGYTNCARGTNGCNGARGAY YTNATGGGNCCNTAYGTNTGGGGNCARTAYGAYYTNYTNGTNYTNCCNCCNTCNTTYCCN TAYGGNGGNATGGARAAYCCNTGYYTNACNTTYGTNACNCCNACNYTNYTNGCNGGNGAY MGNTCNYTNGTNAAYGTNGTNGCNCAYGARATHTCNCAYAGYTGGACNGGNAAYYTNGTN ACNAAYGCNAAYTTYGARCAYTTYTGGYTNAAYGARGGNCAYACNGTNTTYYTNGARMGN AARATHGAYGGNMGNYTNTAYGGNGAR---GAYTGGAARCARYTNCAYTCNCAYGGNGGN TGGACNGGNYTNGGNGARACNATHMGNGAYYTNACNGARGAYGGNCAYGCNCCNTAYACN MGNYTNGTNCCNGAYYTNTGYGGNGTNGAYCCNGAYGARGCNTTYTCNAARGTNCCNTAY GARAARGGNTAYGCNYTNYTNGARCAYYTNGARMGNYTNYTNGGNGGNCCNGAYGTNTTY AAYGTNTTYYTNMGNGCNTAYATHGARCAYTTYAARTAYAARTCNATHYTNACNGARGAY TGGAARAARTTYYTNTTYGGNTAYTTYTCNTCNCCNGAYGAYCARCARAARYTNAAYAGY YTNGAYTGGGAYCARTGGYTNTAYGGNGARGGNATHCCNCCNTTYGARGCNAAYTAYGAY YTNACNYTNGCNCARCCNAGYCAYAGYYTNAGYTCNMGNTGGATHAAY------GAYTCN GAYGARGARMGNTTYTCNCCNGARGAYATHGARAARTGGAGYAGYGAYGTNGTNMGNGAY TTYYTNTCNAGYTTYYTNCAYGCNGARCCNCCNYTNCCNYTNGTNAARGTNAARAARATH CARGARATHTAYGAYTTYAAYGCNGTNMGNAAYTCNGARGTNMGNTTYACNTGGYTNCAR YTNTGYATHCARGCNAARTGGACNGARGCNATHCCNCAYGTNYTNAGYTTYYTNAAYGAR CARGGNMGNATGAARTTYGTNYTNCCNYTNTAYMGNTCNATGAAYAARTGGGARGARGGN MGNAARACNGCNCAYGARAAYTTYYTNCARCAYAARGAYGARATGCAYTCNACNACN--- ------------------------------------------------------------ ---------------------------------------TCNTCNCCNTCNTCNCCNAAR TCNCARCARCARAAYGAYAARMGNGTNMGNMGNGARATHGCNAAYGGNAAYGARMGNMGN MGNATGCARTGYATHAAYGCNGGNTTYACNTCNYTNMGNGCNYTNATHCCNCAYYTNGAR GGNGARAARYTNAGYAARGCNGCNATHYTNCARCARAGYATHGAYTAYATHACNAGYYTN GARAARGAYAARAGYMGNYTNCARATGCARYTNGARMGNACNGCNMGNYTNYTNGCNGAR YTNGGN---CARGARMGNATGYTNGTNGARTCNTAYGTNACNAAYACNCCNCCNCCNACN AARMGNAARAARMGNGAYACN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNATGGARAAYCAYGAR GARATHYTNGAYGCNYTNACNGCNTTYGGNAARAAYCCNAAYCCNCARGARATHCCNTCN GTNYTNGARCARTAYYTNAAYTCNGTNGCNAARAAYGGNGARACNYTNTTYCCNTGGACN CARYTNAARCCNYTNATHYTNMGNAARATGGARYTNGTNATHATGGARYTNMGNMGNAAY YTNGCNTCNGARAAYATHCCNACNMGNCCNAAYGTNGARAAYGTNMGNTTYGAYGTNATH CAYGCNMGNATHATHGAYTCNYTNCAYAARTTYAAYGGNGCNCCNTTYACNATHCARMGN YTNTGYGARYTNYTNATHGAYCCNAARMGNCAYTAYAARMGNAGYGAYAARTTYATGMGN GGNYTNGARAARAAYGTNYTNGTNGTNAGYACNGTNGAYCCNTTYGGNMGNAARGTNGTN TCNGARYTNGGNAAYAARCCNGTNYTNAAYGGNATHYTN---GAYATHAAYGGNTCN--- TTYCCNCCNMGNGAYTCNGCNYTNAGYGTNCCNYTNCCNCCNGTNCCNGGNTGGGTNAAY ACNTCNGCNGTNAAYMGNAAYACNAGYTCNGGNGCNCCNACNATGCCNTCNAAYATGATH AAYAARGCNGGNACNGAYAAYAAYYTNGAYACNYTNGAYAARGAYCCNGAYGGNGTNGTN TCNAAYAGYYTN------TCNCARGTNTTYTCNGAYCARGGNGAY---CCNYTNGCNGTN CARTCNGARGARGTNGTNGARGARACNGTNGTNACNATGGAYACNGGNGARGTNAGYTCN GTNGTNACNGAYGGNGGNGARTCNYTNGCNGARMGNGAYATHGARGCNGAY------ATH GGNGARGAYMGNGAYGCNTCNTCNTCNTCNTCNTCNTCNTCNTCNTCNTCNGARGARYTN TCNACNTCNTCNGAYTCNGARAAYGGNMGNMGNTCNACNTCNCCNYTNGGNATGGTNGGN ACNACNGCNATGGAYGARAAYMGNCCNTGGGCNGCNTTYGCNCARCAYCARGAYGAYYTN GCNACNGCNACNAGYCARTCNAAYATHGAYGARAAYCARTCNTCNTCNTCNCCNCAYAAY ACNYTNACNGCNGAYTCNCCNTCNTCNTCNTGYYTNACNTCNTCNTCNTCNTCNGTNACN TCNGARACNCARTCNTCNYTNYTNTCNACNTCNACNACNGTNACNTCNAARGTNGARGAR TAYGARCARGGNGAYGARAARTCNGTNGGNAAYGTNGCNAAYCARCARACNACNACNTCN TCN---------------------GAYCARTCNAAYTGGAARCARTCNCARAGYGAYGAR GCNCCNGCN---GTNGAYAGYAAYCARAGYTTYGGNTTYGAYCCNGTNGTNCCNTCNCCN CARCARATHACNGAYAARTCNACNGTNACNGAYAARYTNATHTCNTCNACNAGYACNGTN YTNCCNACNACNACNTCNACNACNAAYAAYGCNTCNTCNGAYGTNCAYACNTCNTCNTCN TCNTCNTCNYTNTCN--------------------------------------------- ---------------------GCNAAYGAYGGNGTNGTNGTNACNCARCCNCCN------ ------------ACNTAYGCNCARGTNGTNGCNTCNTCNACN------------ACNGAY MGNATGTCNTCNTCNTCNCCNTCNATHCARCAYATHTCNCCNGCNTGYGAYAGYGTNGCN GGNYTNGARMGNYTNGTNGGNTCNGTNGARCCNTCNYTNTCNTCNTCN------------ ---------------TCNTCNATHTAYTCNYTNTCNTCNGCNTCNTCNCCNCCNTCNTCN ------------------GTNYTNYTNATHCARGTNACNATHACNATHTCNYTNGTNYTN GGNGTNYTNTGYYTNTTYGGNTGYGTNGCNAAYGTNYTNAAYATGATGATHTTYACNAAR ATHGGNTTYAARGAYTCNGTNAAYGTNAGYYTNTTYGGNGTNTCNATGTCNGAYTTYGGN GTNTGYTTYACNTCNYTNYTNTAYGCNATHACNATHAAYCCNYTNATHATHGARTCNAAR TAYCCNATHCAYYTNAGYGGNGTNTCNYTNATGACNATHATHTAYCCNCAYATHATHTGY TTYAARATHACNTAYATGATHACNGCNTTYYTNGGNTTYGARMGNTGYYTNTGYGTNGCN YTNCCNATGAARATH--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TGGACNCARGAY GAYYTNYTNCAYYTNGARAGYGARYTNYTNYTNGCNACNGARGARCCNYTNTGYYTNGAY CCNTCNCCNGCNGTNATGTTYATHGARAAYGCNATHCARTAYGGNGARAARTTYYTNAAY GAYCCNGCNYTNAARMGNTCNGTNAARMGNCAYACNCARGTNGCNACNAAYMGNAARMGN AARYTNGCNCAYTCNGTNGCNCCNGAYAAYATGMGNYTNCAYGAYTTYGTNACNAARMGN AARGGNAARACNAGYYTNTCNAARACNMGNATGATHGTNGAYTCNTTYAARCARACNTCN GAYCCNACNYTNTCNAARCCNGARTCNATHGAYGTNAARAARTAYGCNAARCCNCCNGAR GTNCCNAGYACNAAYGGNATGATHTTYGTNGARGARCAYACNATGGARMGNGAYCCNAAY CARGARCAYCAYATGATGGCNCARATHACNATHTAYCARCCNCARYTNGGNGAYMGNTAY TAYGGNGARTTYTAYYTNGAYCAYGAYTAYGGNCARACNMGNTCNGGNAARGARGGNMGN MGNTGYMGNTTYGTNATHGGNTCNMGNCARTGYGTNGAYMGNTAYYTNCARCARTTYAAR GAYYTNTTYACNGARGARGGNAARYTNCARATGAARATHACNATHMGNAARGCNAAYGAR CCNACNCCNACNATHACNTAYACNCARGGNYTNGCNAAYGCNCCNATHATHCCNCCNGCN GCNCCNACNACNATHGCNYTNAAYACNGCNCARGCNGCNYTNATGAARCARGTNGCNYTN AAYCARCARGCNGTNAARGCNGARATHGGNCCNGCNGTNGCNGGNYTNGCNAAYAARMGN AAYTTYCCNATHCARYTNTCNYTNTCNYTNAGYCCNGCNGGNAAYGCNTCNGCNGGNATH CCNTCNACNYTNTCNACNCARTTYYTNACNACNGCN---------TCNATGGTNGCNAGY CARMGNYTNAAR------ACNCCNAGYCARCAYMGNCCNTCNAGYTCNCCNYTNTCNAGY CCNGTNGCNCCNCCNAARGCNTCNACNCCNCARCARAGYGCNAGYATHCCNYTNATHGCN YTNCCNAARGCNTCNACNCCNACNYTNACNCCNCCNCCNAAYTCNMGNACNCCNACNCCN ACNYTNGCNGGNTCNMGNMGNTCNTCNAAYGAYYTNTCNCARCARATGGCNGCNGGNGTN AGYAAYCARCARACNYTNCARCARCARAAYYTNACNAAYTTYATHCARGGNYTNGCNTCN GGNACNGTNGTNGCNAGYGCNGAYAAYCARAGYACNCARCARCARCARAGYAGYGGNGGN YTNACNAAYYTNAGYATHAGYAAYYTNGGNCARYTNTCNTCNAAYYTNAAYYTNCARGGN YTNGCNGGNYTNTCNGGNGTNAAYATHGCNAAYYTNGGNGGNYTNCARCARATGCARGTN TCNYTNGCNCARATHGCNGTNCCNATHACNATGATHAAYGCNAAYGCNAAYYTNYTNCAR GCNCARCCNGGNATHYTNGCNAAYAGYTCNGCNTCNACNGGNAGYTCNACNGCNACNYTN GTNACNATGGTNACNGCNYTNCCNGCNTCNTCNACNAAYACNACNACNACNACNACNAGY GTNACNGGNTCNTCNGTNGCNGTNTCNACNGGNTCNAAYYTNYTNTCNTTYCCNGTNGGN YTNAGYGGNYTNACNCARYTNATGCCNGTNACNTCNAARGGNCARGCNGGNCARGCNATH MGNCCNACNGCNATGCCNYTNYTNCARYTNCARGGNCARCARGGNATHCARYTNYTNAGY YTN------CARCARMGNGGNCARGTNAARACNAGYAGYTCNAAYACNGCNCARGGNATH ACNMGNYTNGCNCARGCNGGNACNACNACNGTNCCNYTNTCNACNGTNYTNGCNGGNCCN CARATGACNGCNYTNGGNATGGGNAAYAARCCNGGNCARGGNGGNAGYACNGCNATHACN GCNCARCARYTNATHCARYTNACNGGNGCNCARGGNACNTCNYTNGGNCARGGNAAYCAR CCNMGNGCNACNCAYATHACNTTYGGNAARGGNCARCARGGNYTNCARTTYCAYAGYYTN CARYTNAARCARGGNGGNACNACNYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNATHTGGTAYGAYAGYGTNATHGARGAYGGN CARYTNAARTGGCARAAYAARYTNTGYCCNGTNAAYMGNATHTTYTTYGAYGCNTGYGAY GGNATHTTYYTNAAYTAYAAYTGGTCNGCNGCNGAYYTNGARATHTCNGTNTCN---ACN TGYGGNACNGAYMGNMGNCAYGAYATHTAYGTNGGNGTNGAYGTNTTYGGNMGNGGNTGY TTYGGNGGNGGNGGNTGGAAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AGYCCNAAYCCNTCNTCNGAYAARYTNACNGAYCAYAARGAYAAYGGN---GAY GARGGNCAYTCNGAYAARCARGARCARCARAGYCCNAARTCNAGYMGNGARAAYACNCCN GARAARMGNACNAGY------------TCNTCNGAYMGNGARAARACNCCNGAY---AAR GARAARGGNATHAARAARATHAARTCNCCNGAYGARTCNAARCCNTCNACNTCNACNTCN GTNTCNAARGAYGCNCCNTCNACNTCNGCNACNGCNTCNAARTCNCARAARMGNAARAGY GCNGARAGYGAYGARGARYTNAARCARGCNATHAARMGNTAYAARMGNCARGAYGARGAR MGNATGAARATGCARGTNYTNGTNTCNAAYTTYTCNGARGARCARYTNAAYMGNTAYGAR ATGTAYMGNMGNGCNACNTTYCCNMGNGCNTCNATHAARMGNYTNATGCARAAYATHACN GGNTCNGCNGTNTCNCARAAYGTNGTNATHGCNATGTCNGGNATHGCNAARGTNTTYGTN GGNGARGTNYTNGARACNGCNYTNGAYGTNAGYGARAARTGGGGNGAYTCNGGNCCNYTN CAYCCNAARCAYYTNMGNGARGCNGTNMGNGTNYTNAAYACNAARGGNATGATGCCNTCN ACNAARAGYAARAARTCNYTNTTY---------ACNATGGCNATGAARGTNGAYGTNCCN AGYGGNAAYAARYTNGGNTCNGTNCCNGCNATGATGTCNGGNGAYCCNAARACNATGAAR CARGGNYTNATHGTNYTNCARGARTGGTGGGGNYTNAAYGARCARATHCARGAYTGYGGN AARGAYYTNTGY---GGNCARGGNCARATGGTNACNYTNGTNCCNGAYYTNTAYMGNGGN AARGTNGCNACNGAYAAYGARTCNGCNGGNCAYTAYATGGGNAGYYTNGAYTGGCARGGN GCNGTNAGYGAYATHMGNGGNTGYGCNCARTAYYTNAARTCNCARGGNGTNACNAARGTN GCNGTNACNGGNTTYTGYATGGGNGGNGCNYTNTCNATGGCNGGNGCNGCNYTNGTNACN GARATHGAYGCNGCNGTNCCNTTYTAYGGNATHCCNTCNGCNGARYTNTGYGAYGTNACN ACNATHAARATHCCNATGCARTGYCAYTTYGCNYTNAAYGAYCARACNGCNGGNTTYGCN TCNCCNGCNGARTGGAARCCNYTNAARGARAARYTNACNGGNAARYTNGARAARYTNGAR TTYTAYGARTAYGAYGCNGGNCAYGCNTTYACNAAYAARACNGGNGAYAAYTAYAAYAAR GARYTNTGYGAYYTNGCNTTYTCNMGNATGTTYGCNTTYYTNCARAARCAYYTN------ ------------------------------------------------------------ ---------------------AARGAYCCNATGGTNGGNACNTGGGGNMGNYTNAARGAY GTNAAYTCNTCNCAYGCNYTNGAYTAYGGNTGGAGYAGYTCNCAYTGYAGYCARGARATH TTYAAYACNYTNCAYATHGAYACNAARAAYATGYTNTTYAGYCARAARAARCARGCNGTN CCNTTYTAYGCNACNGGNYTNGGNATHYTNGARCCNATHMGNGGNGGNACN---AAYCCN ACNGARAARAAYCARCCNACNGTNGCNCCNACNYTNYTNGAYACNAAYAARTCNGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGGCNGAYTGGAAYTCNGTNGCNGCNGCNYTNAGYAARGTNTCNACN GAYGAYYTNAGYAGYGTNTGYCAYYTNATHGCNGARAGYTTYTGYYTNGAYCARGCNATH GAYTCNGAYCARYTNATHTCNTCNTGGTCNYTNGARGARTGGTGGACNGTNMGNGGNGCN GTNACNGARATGYTNCARMGNGCNGTNCARAARGAYATGACNMGNGAYCARATHCAYAAR GARYTNGARTCNGTNGARGAYTCNCAYAARGCNATHATHTCNGAYGTNATHTCNGTNCAY CAYGCNTCNYTNAARMGNAARYTNYTNCARAAYACNGCNTCNATHTCNCAYGCNGTNYTN TCNGAYTTYGAYTGGAARYTNCARYTNGCNYTNTCNAGYGAYACNATGTCNAGYYTNCAY CARCCNYTNGTNACNYTNGAYYTNGAYATHCARCARGCNAAYGGNGAYATGAARGAYGTN GTNYTNGARATGAAYAARGARGARYTNGCNMGNYTNATHACNTCNYTNGARAGYTGYAGY AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNCAYGCNGGNCAYCAYGARGGNAARCCNYTNGARTTYTCNTCNGAR ATHCAYAAYAARGAYCAYATHATHGARCAYYTNCARMGNCARGTNGCNACNAARCCNAAR GAYCARATGACNGAYGARGARYTNGARTTYCAYTAYTTYAARYTNCAYGAYTAYGAYAAY AAYAAYAARYTNGAYGGNGTNGARATHGGNAARGCNYTNACNCAYTTYCAYGAYGAR--- ------------GAYGCNGAYGTNAARAARGAY---------CCNCCNAARGTNTTYTCN GAYGARGARATHTCNAAYATHGTNGAYTCNGTNATHGAYGARAAYGAYACNAAYAARGAY GGNTAYATHGARTAYTTYGARTTYAARACNAARCARGCNGARGCNAARAARTCNGGNTCN CCNTCNCCNCCNCCNCARCARCARCCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------MGNTCNMGNTCNMGNTCNACNGAYMGNMGN--------------- ACNTCNMGNMGNTCNMGNTCNCARGARGTNMGNMGNTAYMGNTCNTCNMGNGAYMGNMGN MGNTCNMGNTCNGAYTCNMGNGGNMGNAGYMGNMGNTCNMGNTCNMGNTCNGARTCNMGN AAYTAYAGYAAYTAYACNAGYAGYAGYMGNMGNTCNMGNTCNMGNGGNGAYCAYCAYMGN AGY---AGYMGNMGNTCNMGNTCNAARTCNAGYTCNMGNGGNACNACNAAYTCNMGNCAY GGNAGYCCNGAYMGNAARTCNGARCARTCNCAYGGNACNAGYTCN--------------- ------------------------------------------------------------ TCNGARAARGCNGARYTNMGNATGMGNAARGCNTTYCARGCNGCNGCNGCNGCNGAYGAR MGNYTNMGN------AAYYTNMGNGAYGARTCNTCNTCNMGNTCNTCNCCNTCNTCNGCN AAYAAYGGNTTYGCNAGYACNGCNGCNGCNAAYCARAARGAYTTYGCNGAYTCNGTNGCN GCNATHGAYTCNGGNMGNTTYGTNCARTCNTCNTTYAARTCNGGNGGNATHGTNGTNAAR GARGARYTNCCNGAYCCN---YTNATGTCNAGYCAYGAYGAYGCNATHTTYGGNTCNYTN TCNTCNATGGGNTTYACNATHAARCCNGAYCCNGAYYTNAARCCNGTNTCNYTNGAYGCN GAYTCNATHATGCAYCCNMGNYTNTTYTGYAAYGCNGARGAYAARATGGARAARTGGATH GAYMGNYTNGCNCARYTNMGNAARMGNAARATHGARGGNGARGCNATG------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TTYGGNAARGARTAYATGATGAAYATGCARACNAGYAAYGTNAAYTGYGGNCAYYTNAAR ATHGTNCCNGGNGTNTCNAAYGGNGTNGCNTCNATHCARGTNGCNGAYAAYGGNGCNAAY TGYATHGTNATHGTNCCNGGNGCNAAYAGYTAYYTNAGYGARGARGAYGTNATHAAYGCN GARGAYACNATHAARAAYTGYAARGTNYTNATHTGYCARAAYGARATHCCNCARGAYATH TCNYTNTCNGCNGTNAARATHGCNNNNAARCAYAAYGTNAARATHATHTAYAAYCCNGCN CCNGCNGCNTCNAGYYTNYTNCCNGARYTNTTYYTNYTNCCNGAYTAYTTYTGYCCNAAY GARACNGARGCNGARATHYTNACNGGNAAYCCNGTNAARACNGTNGARGAYGCNTTYAAY GCNTGYAARACNYTNCARAAYACNAARGGNTGYAARTCNGTNATHGTNACNYTNGGNGAR AARGGNGCNGTNTAYAARGAYGCNTCNTCNGARGARGCNGTNCAYATHYTNACNTCNCCN GTNAARGCNGTNGAYACNACNATGTCNTTYCCNGGNMGNACNCCNATGGCNATGCCNGGN AGYATGCCNGGNATGCCNCCNMGNATGATGACNACNCCNGGNTAYGCNTTYACNTCNATG GGNATGACNMGNATGAAYCCNATGATGCCNATGCARATGGGNATGATGACNCCNATGATG CARCCNATGATG---CARCCNCARATGCARATGCARCCNCARCARCARCAYATGAARCAR AAYCARAARTTYGTNCCNCARGARATHCCNAARAGYGAYCCNAARGGNGARAARCCNCCN GTNACNACNGTNTTYGTNGGNAAYATHAGYGAYMGNGCNCCNGAYATGATGATHAARCAR ATGYTNCARMGNTGYGGNAAYGTNYTNAGYTGGAARMGNGTNCARGGNGCNTCNGGNAAR YTNCARGCNTTYGGNTTYTGYGARTAYGARGAYCCNGARGCNACNYTNMGNTGYATHMGN YTNYTNAAYGAYTGGCCNATHTCNAAYAARAAYYTNGTNGTNAARGTNGAYGCNAARACN AARACNYTNYTNGAYGAYTAYMGNAARAARAARCARGGNAAYGAR------GARGGNGCN AARAARGGNTCNGAYACNAAYGARAARGARAARGGNGARGARGARAAYGGNGARGTNAAR GARGAYCCNGAYACNGGNAARGAYGARATHGARGAYAARGARGGNGARYTNGAYGARAAY ACNMGNMGNGARGAYMGNYTNGCNCARGCNGGNYTNGARGCNATHATGAARGARTAYGCN TTYGARYTNGCNAARGARCCNGCNAARTCNTCNGAYGGNGGNGAYCAYGARAARGARAAR CARGCNCCNAARAARGAYAARGARATHTAYATGCAYGCNAARGAYACNGGNTTYGAYGAY ATGGARATGGARGAYGARAARMGNCARATHATHAAYMGNGARATHAAYAARTTYMGNGAY MGNCAYAARGAYGCNGAYGARGARAARGARAARGAYAAYMGNGARAARGARMGNAGYATH GCNMGNGARMGNGAYMGNMGNCARGARGARAARMGNCAYMGNGARMGNYTNGARAARYTN MGNGARCARCAR---------------MGNGARACNCAYMGNGARMGNGARMGNCCNTCN ACNMGNATHTCNMGNTCNAARTCNMGNTCNGTNTCNCCNGTNCCNTCNMGNTCNMGNMGN MGNTCNMGNTCN------------MGNGARMGNACNAGYMGNGAYMGNTCNMGNGARMGN MGNAARGARMGNGARATHGARGARGARGARGARYTNTAYGARMGNMGNAARYTNGARAAR AARYTNMGNGARAARGARGCNGCNTAYCARGARMGNYTNAARAAYTGGGARGGNMGNGAR MGNAARAARACNMGNGARTAYGARAARGARGGNGAYMGNGARGARGARMGNAARGTNGAR GARGGNMGNGARGCNMGNMGNYTNAARGARTTYYTNGARGAYTAYGAYGAYYTNMGNGAY GAYCCNAARTTYTAYAARGGNAGYGCNYTNCARMGNMGNCARAARGARMGNGARAARGAR AARGARYTNGAYAAYMGNGAYMGNCARMGNGARAARGARGARTTYGARGARATHAARMGN AARYTNTTYGAYGARGGNCAYCCNGAYGCNGARACNGARGTNGCNMGNATGGARMGNGAR MGNGARGARCAYYTNCARCCNTGYYTNCARYTNCARGARYTNAARCARCCNCCNCARCCN GTNYTNAGYMGNGAYTAYGAYTCNGAYGAYGARCCN------CCNTCNTCNGGNATHGGN GARATHMGNCARCCNCCNTCNCCNAARGARACNGARCAYCARCCNMGNAAYGGNYTNCAY AAYCARCARCARCARCARYTNACNGCNCAYCAYCAYCARCARCARCARCARCARCAYMGN CCNTCNCCNTCNYTNTCNACNTCNCCNATHTCNACNGAYTCNMGNGTNAGYAGYNNNNNN NNNYTNTGYATGGAYGARCCNTCNCARTCNTCNTTYCCNCCNACNGGNGCNYTNCCNATG TCNTCNCCNTAY---GGNGARGCNMGNYTNGGNTTYAARCAYTCNTCNGCNTCNACNTCN TCNYTNAAYYTNGCNCCNGGNATHAGYCCNGAYTCNTCNAGYYTNCCNGGNGTNACNAAY YTNTCNGAYGGNAARMGNAARAARYTNACNGTNGGNGAYGTNTTYAAYCARGAYGAYGAY GAYAGYAAYGARCCNAARAARMGNAARYTNATHCCNYTNGAYTAYGAYGARGAYAARTCN ACNCCNACNGAYAARAARGGNGCNACNGCNGARGARAARMGNCARAARATHAARCARYTN ATHGARAAYATHCCNACNGCNAARGAYGARYTNTAYGCNTAYACNGTNGAYTGGGAYATH GTNGAYCARGCNYTNATGGAYAARMGNATHAARCCNTGGGTNACNAARAARATHGTNGAR TAYATHGGNGARGARGARCCNACNYTNACNGARTTYATHTGYCARAARGTNATHGCNMGN AGYACNCCNCARAGYATHCARAAYGAYGTNGCNATGATHYTNGAYGARGARGCNGARGTN TTYGTNGTNAARATGTGGMGNYTNYTNGTNTAYGARACNGARGCNAARAARYTNGGNYTN GTNAARYTNGTNACNGARGARTAYAAYAARCAR---GTNCCNYTNTGGCCNCARGARGGN AARCAYATHYTNGCNCAYTAYGAYGAYGARACNGTNGTNGTNTAYCARGCNTAYAAYCCN AARATHGCNAGYTAYGCNGTNAARTAYCARCARTTYGGNGGNCCNGAYTTYAARTAYACN MGNATGTCNTGGATHAARCCNAAYTTYATGTGGATGATGTAYMGNTGYGGNTGGGCNCAR AARCARAAYCARGARMGNGTNYTNGCNGTNMGNYTNACNAARCARGGNTTYGARAAYATH YTNGCNGCNGCNAARTCNGGNMGNGARGGNGAYCARGARTCNAARAARGCNGAY------ GARGTNMGNATHCARTGGGAYCCNGAYCAYGGNCCNCAYGGNGAR---AGYYTNACNMGN MGNGCNATHCARYTNGGNATGMGNGGNATGGGNAAYTGYGTNCAYMGNTGYTTYGGNGTN ATHGAYMGNMGNAARMGNTAYYTNMGNTCNAARTAYAGYGARGARCARAAYTTYTCNATH GARTTYGARAAYYTNATGGARGARGARCCNCARGAYGARATGTCNMGNYTNYTNACNGAY MGNGARAARCARYTNYTNAARACNAARCARTTYACNGCNYTNGCNCARGARCARYTNMGN GTNGAYYTNGARATHGAYGCNAARYTNAARCARGARYTNGARMGNGARGARGARGCNTTY TAYGARGCNAARMGNGARGCNGCNMGNATHGCNAARATGAAYAARGCNAARGARCARGCN GCNAARAARCAYYTNGCNAAYGGNGGNAGYGCNAAYGAYGARGARTGGGARATHGCNGGN GGNGARGAYGAYTTYGARATGTTYYTNGCNAAYGTNAARGCNMGNTCNYTNGCNACNATH TCNCARGTNAARAAYGGNTCNGGNGAYGGNCAYAGYTCNAGYAGYAGYAAYGCNCAYACN AARGCNAGYTCNYTNGAYATGGARTGGGARCAYGARGTNGGNATGTCNCCNAGYAARMGN CCNCCNCARGTNTCNGTNTCNGARGAYAAYTGGTCNAARACNTCNACNGCNAGYCCNYTN CAYTCNAGYGAYYTNGARTGGGAYCCNGAYTTYGTNTCNGCNGAYGAYAAYGARMGNYTN CARYTNATHTCNAARGGNTTYATHCCNAARMGNMGNCCNATHCCNMGNYTNGGNCARGTN GGNGGNACNGGNMGNTTYTGYGTNATHGTNGAYGCNGARAGYTGYYTNGAYMGNYTNTAY GGNGGNTAYTTYTCNGAYTGGGTNTGYGGNGGNCARTGGAAYMGNATGACNGCNTTYYTN GCNAAYYTNGTNTCNGCNTGYCAYAAYGGNAAYATGGARYTNGTNGTNTTYTTYAAYGGN GCNYTNGARAAYCARAARATHAAYGARTGGATGCCNCAYCARYTNTCNCARMGNGAYAAR GTNMGNTAYGTNYTNMGNCAYATHTCNAAYAARGGNACNCCNCCNCCNAARATHTGGTGG AAYCARCCNGTNTTYYTNAARGARGCNYTNAARATGGCNYTNMGNCARYTNGGNGTNACN GTNGCNTGYTCNYTNGAYGAYCAYCAYCARGARGTNATHAARTTYTGYMGNGARCAYACN YTNCARGGNATHATHGCNCARGARTCNGTNTAYACNATHTTYGAYCCNCCNMGNTAYTTY TCNTCNAAYAAYYTNAARYTNACNTAYAARGGNTCNYTNGARACNAARGARTAYATHATG GAYGARGTNGCNAARTGYATGAAYYTNAAYCCNAAYMGNTTYTGYGTNTTYGCNGCNYTN YTNGGNAAYCAYATHYTNACNGAYGARGAYYTNGTNCCNTTYMGNGARAGYYTNCCNGCN CCNGAYGGNGGNAARCCNMGNMGNCCNMGNGAYAARYTNGAYGCNCCNATGATHAARGCN ATHTGYGAYTAYGTNMGNAAYYTNCARTCNGTNGAYAAYTGGGARTCNGTNGGNAAYGAY GCNTTYAARYTNGCNAARAAYAAYAARGCNGAYYTNGTNGAYMGNTTYAARAARAGYGTN AARTAYTAYGTNAGYGGNACNCARGARGGNTAYTTYAARTAYGTNYTNAAYMGNGGNCCN YTNATGTCNCARCCNATGTAYAGYGGNGGNCAYCCNCCNYTNCAYGCNTAYGAYGARCAY AARCARCAYGGNCAYGCNATGGGNGAYGCNGGNGGNTCNMGNAGYCCNGGNYTNCCNCCN GTNTCNAAYGARATHATGMGNGTNGCNATHGAYMGNCAYCARAARGGNYTNATGCAYCCN YTNATHTAYCARGTNYTNACNCARGGNGARGTNAARYTNCCNGTNATHYTNGARGAYGAY ACNCCNMGNGAYYTNCCNAGYTAYATHGAYYTNTAYMGNCCNATHMGNCARACNGTNTAY TCNGTNYTNYTNAAYYTNAAYAARCARAARATHGTNCAYGARATHCARAAYAARGARAAR TCNAARAARCCNCARGGNGAYTTYACNGCNCARGTNAARGARTGGGTNGTNMGNMGNGGN TCNGGNMGNGCNGCNTAYGARGTNGTNACNGCNMGNCCNGTNGARTGGAARACNCCNAGY GTNCARMGNATGTGGYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATGGCNGAYGARTCNGAYATHCCNCCNYTNGARGAYATGACNGAYGTNYTNCAR AARGCNGARYTNATHMGNGARCARMGNTTYGGNTCNACNGGNCARGCNCCNAGYAARTCN AARAGYGARGGNGCNAARAARMGNGCNAARGTNACNAARAARAAYGTNGGNAAYACNGAR GTNGCNTCNGARCAR---GARAARGTNCAYAGY--------------------------- ------------------------------------------------CCNAAYACNCCN GARAARAARAARGARGAYMGNTCNAARAGYCCNGGNATGTTYGGNGGNATGAARAARGGN TTYYTNTTYGGNGGN---CCNAGYAARACNTCNTCNAARCCNTCNTCNAAYGCNAGYGGN AAYGTNATGAARACNAARAGYTCNACNGARAARGCN------------------------ ---------------CAYAARGARGAYATHCCNTTYATHACNCCNTCNGGNAARACNAAR GCNGAYYTNACNTTYAAYGARGTNCARCARGCNATGTCNGARGCNAARGGNYTNYTNGAY GAYCARGARTGGATHACNGAYGAYTTYYTNAGYACNATHGARAARAAYGAYACNYTNYTN AARMGNTTYAGYGAYCCNCARTTYATGTCNGCNYTNCARGARTTYCARACNAAYCCNCAR GCNGCNATGGTNAARTAYAARGGNAAYCARGARGTNGARAARTTYYTNATGGARTTYTGY GGNYTNYTNGGNGAYCAYTTYACNAARYTNGGNAGYAGYGGNGAYAAYCARAARTCNTGY CARACNCCNGAYACNGARGCNCARTCNGCNGCNAARTCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GTNAARGAYAGYTCNAARMGNTCNTTYTTYATHAAR GTNTTYGAYATHAARAARCARCARATGATHTGGGARCARGARYTNTAYAAYCARTTYGTN TAYAARACNCCNMGNGARTAYTTYCAYACNTTYGARGCNCARAAYTGYCARGCNGGNYTN AAYTTYGCNCAYGARGAYGARGCNATHAARTTYAARAARGCNGTNGARGGNAARYTNAAY GARMGNMGNCARAARAARATHGARMGNAARCARAARTCNGTN------TAYCAYAAR--- ------GGNGGNAAYGAYCAYGGNCARGCNAAYCCNCCNCARMGNATGGGNGGNGTNACN CCNGCNGCNCCNACNCARACNGTNACNGTNGAYGTNAGYMGNATGAAYAAY--------- ------AARGARAARAARGAYAARGAYAARAARAARGAYGCNAARAARAARYTNACNAAR GCNGAYATHGGNACNCCNTCNAAYTTYGTNCAYGTNAGYCAYGTNGGNTGGGAYCCNGAY AARGGNTTYGAYATGAAYAAYYTNGARCCNGAYATGCARACNYTNTTYCARTCNGTNGGN ATHAARCCNGARGAYAARGTNGAYAARGARACNGTNGAYTTYATHTAYGAYTTYGTNGAR AARCARGGNGGNATGGARGCNTTYAGYMGNGARYTNMGNAARAAYCAR------GGNMGN CCNCCNCCNCCNCCNGCNTCNATHGGNMGNAGYGGNGGNGCNCCNCCNCCNCCNCCNGCN MGNTCNCCNGGNGGNCCNCCN--------------------------------------- ------ATGGCNCCNCCNCCN---CARMGNGGNGGNGCNCCNCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGGCNTCNYTNTTYGGNGARCAYMGNYTNYTNACNAARAARGTN TTYGAYGARATGTAYATHCCNGARAARGAYAARGAYAAYTAYAAYACNGTNCARGCNAAY GARGCNYTNGARGGNAARGTNGTNTGYYTNTTYTTYTCNGCNTCNTGGTGYACNCCNTGY CARCAYTTYGTNCCNACNYTNAARGARACNTAYACNGARYTNGTNCAYMGNAAYAGYCCN YTNGARGTNGTNTTYYTNAGYTTYGAYAARACNGARGARGAYATGATGAGYTAYTAYCAR GARAARCAYGGNGAYTGGYTNTGYGTNAARTTYGAYGAYTCNYTNAARCARGARYTNGTN GARMGNTAYTCNATHAGYGTNATHCCNAARYTNATHGTNATHCARCCNGAYGGNGARGTN ATHAGYAGYAARGGNMGNAARGAYGTNCARGAYMGNGGNGTNGTNTGYATGMGNACNTGG CARGCNGGNTTYGAYAARTAYATGCAYCAYGAYAARGARCAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AAYGTNTCNGGNATGMGNAARCCNTAYAARGGNAAR CARGAYGTNTTYGAYGTNAARGAYYTNATHTCNAARGARCCNTTYGARCARTTYAAYGCN TGGTTYGARGARGCNAARTCNACNCCNGARATHTTYGARGCNAAYGCNATGGCNYTNGCN ACNGCNAGYAGYTCNGGNAARCCNTCNGTNMGNATGGTNYTNATGAARGGNYTNAGYAAR GAYGGNATHGAYTTYTAYACNAAYTAYCAYAGYMGNAARTCNCARGAYYTNATHGARAAY CCNCARTGYAGYYTNATGTTYTAYTGGGARAARYTNAAYAARTCNGTNMGNATHGARGGN AARGTNGARAARYTNCCNCARGARCAYTCNGARAAYTAYTTYCAYTCNMGNCCNMGNTCN AGYCARATHGGNGCNTGYGTNAGYGARMGN---CARAGYTCNGCNATHTCNTCNMGNGAR GTNYTNGAYAARMGNAARGARCAYYTNGARTCNCARTAYAGYGAYGARAGYATHTCNATH CCNAARCCNGAYTAYTGGGGNGGNTTYMGNGTNGTNCCNGAYMGNTAYGARTTYTGGCAR GGNCARACNAAYMGNATHCAYGAYMGNATHGTNTTYMGNAARCCNCARTCNGGNGARAAR ATHGAYCCNTCNGTNACNTTYGARGGNAAYGARGGNTGGGTNTAYGARMGNYTNCARCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CCN AGYGGNATHYTNGCNMGNGTN------MGNGGNTTYMGNAGYAARAARAGYACNTCNGAY GTNTCNAAYCARGTNGAYAARACNMGNCCNGAYGGNAAYTAYTCNYTNATHAARTCNGCN ACNTTYGTNACNGGNGTNTGYAGYTGYAGYTTYGTNGGNGCNATGATHTGGAAYTAYGAR AARGTNMGNAARATGTAY---------------ACNGARMGNTCNTCNGARAGYATHTCN CAYCARCAYTTYGAYAARGCNTTYGGNTTYMGNTCNCAYYTNAAYGCNATGTGGAARAAY ATHGAYTCNTCNACNAARYTNGTNTTYGGNATHATHGCNGTNAAYGTNGCNGTNTGGGGN YTNYTNMGNGTNCCNMGNYTNCARGCNGAYATGATHMGNTAYTTYTTYTCNTCNGCNGCN AAYCCNMGNGTNTCNATGGTNYTNAGYAGYTTYACNCAYATHAGYGTNATHCAYYTNTTY ATHAAYATGTAYGTNYTNYTNTCNTTYGCNCCNGTNGCNACNMGNACNTTYGGNGCNGAR CARTTYTCNGCNTTYTAYATHAGYGCNGGNACNGTNTCNGCNTTYGCNAGYATHYTNTGY CARMGNYTNYTNAARMGNCCNYTNTCNYTNTCNATHGGNGCNTCNGGNGCNATHATGGGN YTNYTNGGNGTNACNGGNATHYTNTAYCCNAAYGCNCARYTNCARATHGCNYTNGTNTCN GARATHTTYCCNCAYTCNTTYTCNGCNCARACNGGNATHACNGCNATHGTNYTNTTYGAY YTNYTNGGNYTNTTYATGGGNTGGAARGTNYTNGAYCAYGCNGGNCAYYTNGGNGGNATG YTNTTYGGNATHYTNTAYGCNAARTAYGGNAAYCARATGGTNTGGGGNAAYMGNGARTCN YTNGTNAARATGTGGCAYAAYATHMGNGGNAARCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNAGYTCNAGYMGNGGNAGYCCNAARTCNTCNAAYMGNMGNACNGARTCNCCNACNYTN ACNATHGCNAARACNCCNAAYYTNAGYACNMGNGGNMGNTCNMGNTCNCARAARCAYYTN ACNMGNGARGARGARGARGARATHGARTAYGARAARCAYMGNCARCARCARTTYAARGCN CAYAARGTNAAYCAYAARATHYTNCARGARTCNTCNTTYGGNGTNMGNMGNGTNCCNTCN AARCCNCCNACNATGGTNAARGARTTYAAYYTNCAYACNACNAGYTCNATHCAYMGNAAR GGNTCNAGYGAYTCNACNGAY---GGNAARGCNAGYGCNTTYCAYGCNCAYCCNGTNAAY CARAARATHYTNGAYGGNCCNACNGGNATHAARCCNGCNGARMGNMGNCCNATHACNGTN GCNCARTCNCCNGCNTTYTCNYTNAARAAYMGNYTNMGNACNCCNGTNGARGTNGTNTCN CCNGARCCNCCNAARGTNTCNTCNMGNACN------GTNCCNCAYATGGGNGTNCCNTTY MGNCCNCAYYTNGARCAYAARTAYACNGTNACNAARCCNTTYGCNGTNGARAARCAYAGY AARGAYATGYTNGARAARMGNGAYCARAARATHCARCARATHYTNGARGARGARAARAAR GCNMGNGARTTYCAYGCNAGYYTNYTNCCNAGYGAYAGYCCNGAYCARYTNCCNCCNAAR AARACNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CAYATHGARGGNTCNACNGAYGAYCCNCAYGGNGGNGTNCCNATGGGN ATHCCNAAYTCNTTYTGYGAYGAYGGNAARAGYTAYYTNTCNATHGAYTGGGAYCCNTCN TCNACNGAYGARTAYACNTGYACNGARGAYGARAARGAYACNYTNGGNGAYAAYGARGCN YTNTCNAAYAGYTTYGARGARTGYGARCARATHGCNAARMGNCCNGTNCAYGTNTGYTAY CCNGARAARATHCAYTAYGAYGARGAYYTNCCNACNAGYGGNMGNCAYMGNCCNYTNTGG CCNAARTAYGGNGARTAYAARTAYYTNCCNCCNGARMGNTGGYTNCAYTCNYTNGARCAY GGNGCNATHGTNTTYYTNTAYAAYCCNTGYACNGAYAARMGNCARGTNGAYAARTTYAAR GCNYTNGCNMGNGGNTGYYTNMGNMGNCAYGTNATHTCNCCNTCNAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARCCNTTYGAYTCNAARAAR AARAGYMGNATHGAYGAYGARYTNYTNCCNGAYYTNGAYGAYGCNGTNYTNMGNYTNGCN MGNATGMGNAARAAYCARGTNTCNAARTGYAARTCNYTNGCNMGNAGYACNGTNGCNAAY TCNGTNAARTAYTAYAGYCAYYTNACNGTNGARAGYGARTCNYTNGGNGAYGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AGYYTNTCNGGNGGNAAYCARCCNGGNAGYATGGARACNYTNAARAAYATG YTNTTYAARYTNCARAARGARGARAGYTCNGTNACNACNAAYAAYGCNACNGCNGAYGCN CCNYTNCCNGCNYTNCARGAYTAYGAYTTYCARACNGARCCNGGNGGNCAYTCNYTNGAR AARGCNYTNCAYCAYYTNGAYMGNYTNAAR------AAYGGNGAYAGYTGYAAYACNGGN CCNGTNGTNGTNGTNCAYAARYTNGAYGAYGARTCNGCNTTYCCNTAYGCNGGNMGNGAR GGNCARGTNGCNTGYAGYGTNTAYAAYAARGTNTAYGTNTTYGGNGGNGTNGARCARGGN CARGGNGAYGARCCNAARGARACNAAYGARYTNYTNGTNTTYGAYYTNGCNTCNCARAAR TGGTCNAARCCNYTNGTNYTNGGNTCNCCNCCNCCNCCNMGNTCNGCNGCNTCNYTNACN GCNGTNGGNACNAARYTNTAYYTNTTYGGNGGNYTNAGYCAYATHTGYGGNTGGTTYGAY GAYGTNCAYGTNTTYGAYATHGTNACNAAYTCNTGGTCNYTNYTNGARACNGAYGGNACN AARCCNMGNGCNMGNGAYAARYTNCARGCNGTNGTNTTYGAYACNAAYATHTAYTAYTTY GGNGGNTTYGGNCCNAARTCNGAYGARGCNGARGTNGAYGAYYTNGCNGGNGAYGAYGAY GAYGAYTAYGARGAYGARGARGAYATHCCNGARAGYMGNGARCARGAYGGNGCNGARTTY GGNTGGTTYAAYGAYYTNTGGGTNYTNGAYACNYTNACNYTNAARTGGTTYCARCCNATG CARATGAAYYTNGGNGTNCCNACNCARMGNGCNGCNCAYGGNATGTGYGCNGTNGGNMGN AAYATHGTNATHTTYGGNGGNMGNGAYATHGARGAYMGNCARAAYGAYGTNCAYATHTTY AAYATHGAYACNMGNAARTGGGAYACNGAYYTNAARYTNACNGGNCARTCNCCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGTAYTCNGCNCAYACNGARGGN TCNYTNGTNATGCARCCNYTNYTNTAYCARTTYCCNACNGAYACNGCNACNYTNAGYATH GAYACNCARTTYATGYTNGGNGAYGCNYTNYTNGTNTCNCCNGTNYTNGAYGARGGNGAR ACNAGYGTNCARGCNTAYTTYCCNCARGGNMGNTGGTAYGAYTAYYTNACNGGNCARGAR ATHGCNAGYGGNGGNAARACNGTNGARYTNGCNACNCCNYTNAAYAARTTYAAYGTNCAY ATHMGNGGNGGNCAYGTNGTNCCNTGGCARCARCCNGGNATGACNACNTAYGARAGYMGN CARAAYAARYTNGGNYTNATHGTNGCNYTNGAYGARACNGGNAARGCNAAYGGNGARATG TTYTGGGAYGAYGGNGARCAYAARGTNACNCCNTCNAAYTAYAAYATGATHAGYTTYACN ATGGARAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TCNTAYATGAARAAYACNTCNCCNMGNYTNYTNCCNTCNTCNTTY GTNTAYCCNAAYATHTAYCCNTCNCARYTNATHGTNCCNTCNGGNGARAARACNTAYGAR YTNATHGGNATGYTNACNATHACNGAYTTYATHAAYATHYTNAARCARTAYTAYAARGTN TCNGGNAARAARATHGARGARYTNGARGARCAYAARATHTCNACNTGGMGNGARGTNYTN AARGGNAARCARAARCCNTTYGTNTCNATHTGYCCNGAYCARAGYYTNTTYGAYGCNGTN AARACNYTNGTNGAYCAYCARGTNCAYMGNYTNCCNGTNATHGAYGARACNACNGGNAAY GCNYTNTAYATHYTNACNCAYAARMGNATHYTNMGNTTYATGCAYYTNTTYNNNAARGAY YTNCCNCAYCCNGCNTAYATGAARAARTCNATHAARGARYTNGGNATHGGNACNTAYGAR AAYGTNATHACNGCNACNCCNGAYATGACNYTNATHGCNGTNYTNAAYYTNTTYTCNGAY AAYMGNATHTCNGCNYTNCCNGTNGTNGAYACNAAYTCNGGNAARATHATHGGNATHTAY GCNAARTTYGAYGTNATHAAYYTNGCNGCNGARAARACNTAYGAYAAYYTNGAYATHACN YTNAARGARGCNYTNGAYMGNMGN---TTYGAYAAYCAYGARGCNGGNGARAARGTNGTN TCNTGYCARGGNACNGAYYTNYTNGARGAYGTNGTNAAYAARATHGTNAARGCNGARGTN CAYMGNYTNGTNGTNGTNGAYGARTGYGGNGCNGTNGAYGGNATHATHTCNYTNTCNGAY YTNYTNAAYTAYACNGTNYTNMGNCCNGTNGARGARGTNTCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CARAARATHCARGAYCCNTAY AGYYTNGTNACNAAYAAYMGNATGACNGARTGGGARAARTCNMGNGARMGNGAYGARTTY AGYMGNTCNGCNAARYTNTAYMGNCCNATGTCNGCNATGATGTCNGCNMGNTTYGTNCAR GGNGCNATGYTNGAYGAYAARAAYCARGAYTCNAARATGGARGAYAGYGARGARGCNACN GAYGARGTNAARGCNTCNGARATGMGNATGTTYGGNAARYTNACNMGNGARGARTTYGAR TGGCAYCCNGAYAARYTNGTNTGYAARMGNTTYAAYGTNCCNAAYCCNTAYCCNGGNTCN GAYATHGTNGGNYTNCCNACNGTNAARMGNGAYAARTTYTCNGTNTTYAAYTTYYTNAGY TTYGGNGAYTAYMGNCCNAARGARTCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TCNYTNGCNGTNTGYGTNAARACNGAYGAYGCNCARACNGTN MGNAARATHYTNGARGARAAYAAYTTYTGGGAYAARAGYYTNAARYTNAARYTNATHGGN GARACNGTNGCNATHCCNATHTGYGGNAARGTNGGNCCNAARYTNTGGMGNYTNYTNGAR GAYTTYCCNGGNGCNAARATHGTNGARMGNTGYYTNYTNAGYACNMGNAAY------MGN YTNTCNGAYTTYCCNGTNGAYYTNYTNCARGARGTNCCNMGNAARTGGGARAARCAYGGN GAYYTNGTNYTNYTNCCNTCNATGGCNTTYACNTCNCCNGTNTGGAAYCAYYTNGGNGAY GARYTNTGGCAYACNGTNGCNTCNTCNYTNTCNTGYCAYMGNGTNGCNMGNYTNTCNMGN GTNTCNACNGAYGGNTAYMGNACNCCNCARGTNACNYTNYTNYTNGGNCAYCAYGGNAAY GTNATGCAYATHGAYAAYGGNATHAARTAYACNTTYGAYGTNACNAARTGYATGTTYAGY TCNGGNAAYATHACNGARAARYTNMGNGTNGCNTCNTGGGAYTGYTCNAAYGARGTNATH GTNGAYYTNTAYGCNGGNATHGGNTAYTTYACNYTNCCNTAYYTNGTNCAYGCNAARGCN ATHCAYGTNCAYGCNTGYGARTGGAAYCCNTAYGCNGTNGAYGCNYTNMGNAARGCNYTN GARYTNAAYGGNGTNACNGAYMGNTGYACNATHTAYCCNGGNGAYAAYMGNCARGTNAAR YTNCAYGAYGTNGCNGAYMGNGTNAAYYTNGGNYTNATHCCNAGYAGY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARATGYTNCAYGAYGAR YTNGTNMGNAARGAYAAYCARATGAARYTNGAYGTNGARGAYYTNTGGGAYMGNYTNAAR GCNYTNTGGAGYMGNYTNGARACNCCNGARATHGARMGNGARGCNTTYTCNYTNGAYMGN ACNGGNCAYGGNCARAARGTNATGAAYGAYYTNAARTCNGARATHTCNGTNTGYGARGAR YTNAARYTNCARAAYATHCARAARTTYATHGARGGNATHMGNACNGARYTNGTNTCNTGG TGGGAYAARTGYTTYTTYGAYCCNCARGARMGNAARAAYTTYACNYTNTAYTAYGARGAY AAYTTYACNGARTCNYTNYTNGARGCNCAYGARCARGARYTNGARAARGTNMGNGAYTAY TAYAARGARCAYMGNGARYTNYTNGAYAARGTNACNMGNMGNGARGGNYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GCNGGNGGNATGGARAAYGCNGTNGAYGCNYTNGARGGNATGTTYAAYAARGCN GARAARGAYYTNGAYTAYATGTCNMGNAARYTNGAYAARCARYTNGARTGYGTNAAYGAR GGNGAYCCNACNGCNAAYCCNGTNAARYTNATGAARAARYTNGARYTNATHAARACNGAR TAYGCNAAYGTNGTNCARGAYGTNMGNGAYATHCARAAYGCNCARAARGARTTYTCNGAY ATGTTYMGNTCNCARYTNYTNACNYTNACNGAYGTNYTNCARMGNYTNGARATGAGYACN GGNCARTCNTCNGARAARAGYGARGARGARAARGAYGTNTTYGAYCARYTNTCNAAYYTN YTNGGNATH------------------CCNCCNGGNCARYTNGAYTCNCCNTCNTGYGAR GAYACNAAYAARAAYGGNAGYGCNTCNGTNTCNGARTCNTCNTCNTCNGARGCNGTNACN AAYGGNGCNGARTCNAARGCNCAYAGYAARGGNACNAARACNGCNTCNAARACNGCNAAY GGNTCNAARACNAARGGNCCNGARTTYTGYGARATHTCNGTNGARGARTTYCARTCNYTN TCNAARYTNGTNACNCARMGNTGYAARATHGARGAYGTNAAYAARGTNTAYMGNMGNYTN TGGCARCAYTTYMGNGARGARAARAAYAARAGYAARYTNACNCCNAARGARATGAAYGCN ATGGGNYTNAARGTNACNGGNGCNACNGGNGARGCNAARYTNAARGTNYTNMGNGCNYTN AARYTNTGYACNATHGAYAARGAYGGNGGNGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGTAYTCN ACNTGYGGNACNTCNTAYGTNTAYACNATHTAYGGNATGTAYTTYTGYTTYAAYATHTCN AGYCARGAYACNGGNGGNTGYGCNYTNATHMGNGGNYTNGARCCNYTNTCNGGNYTNGAR AARATG---------MGNGTNAAYMGNTCNGTNAAR------MGNTCNCCNCCNYTNAAR YTNAAYCAYYTNTGYAGYGGNCCNTCNAARYTNTGYCARGCNATGAAYATH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CARCARYTNAAYACNAAYGGNGAYGGNGAYGGNAAYTGYGCNTAYAAY TGGACNACNAAYAARTAYGCNMGNTGYGTNAARGARGAYGTNATGTGYATGTCNACNTCN TCNGAYCAYACNGARTCNTCNCCNMGNCARTCNCCNTCNCCNTCNCCNMGNAGYGCNAGY GAYGGNMGNCARYTNCCNAGYATHCCNACNTCNCARACNCAYTCNACNGGN------TCN TCNAAYAARAGYAAYAAYCARTCNAAYAGYGTNAARGGNAGYAAYGGNTAYGGNCCNTTY TTYCARGARTAYTCNYTNATGGCNGARTTYAAYCARGTNCAYCAYCARAAYATHCCNGGN YTNTAYGCNATGCCNTCNTCNAARTCNCCNYTNATHTGGTCNGGNGTNATHTTYATHMGN CARGGNYTNTAYCARGGNGCNGCNYTNMGNTTYACNYTNACNATHCCNCAYAAYTAYCCN GAYGGNAAYTGYCCNACNYTNGTNTTYGARCAYCCNGTNTTYCAYCCNYTNGTNGAYCCN GAYACNGGNGARYTNGAYGTNAARMGNGCNTTYCCNMGNTGGMGNMGNAAYGTNAAYCAY YTNTGGCARGTNYTNYTNTTYGCNAARAARGTNTTYTAYAAYATHGAYACNAARGTNCCN TCNAAYCCNGARGCNGCNGTNYTNTAYGAYMGNGARCARGARYTNTTYAARAGYAARGTN TCNGARTCNGTNGARGCNGCNMGNGARMGNYTNTAYCARCCNCCNTCNYTNGAYGAYCCN TTYGCNYTNMGNTTYAGYCCNTGGAAYGARGCNGTNCAYCCNGAYACNMGNMGNCARATG YTNCARACNTCNAARAAR---TGYGAYGGNGAYAAYTCNGCNAAYCCNTCNGAYYTNGGN YTNAGYTGGATGGARTCN------ACNCAYATHTTYGCNTCNGAYAAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GGNATGGTNTCNGCNATGGAYGAR GGNGTNGGNAAYYTNACNTCNGCNYTNAARGARGARGGNYTNTGGGAYAAYACNGTNTTY GTNTTYTCNACNGAYAAYGGNGGNCARGTNYTNGCNGGNGGNAAYAAYTTYCCNYTNMGN GGNTGGAARGGNTCNYTNTGGGARGGNGGNTTYCAYGGNATHGGNTTYGTNTCNGGNCCN YTNGTNAARTCNCCNGGNACNGTNAAYAARGARYTNATHCAYGTNACNGAYTGGTAYCCN ACNYTNGTNAARYTNGCNGGNGGNAGYYTNAAYGGNACNAARCCNATHGAYGGNTAYGAY CARTGGGAYGCNATHAGYTCNTGYACNACNTTYCCNMGNCAYGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GGNGTNTTYGARACN AGYACNACNACNACNAARGCNAAYGAYTCNCAYYTNATGGTNGCNATHGARAGYGAYGCN CAYTGGYTNGCNYTNTAYYTNGAYAAYGARGAYGGNMGNGARYTNACNGARGTNGAYGTN GARGTNCCNATHYTNGARATHATHCCNAARGGNGAYATHGTNTAYACNCCNGGNCARAAY GCNACNTTYGAYATHCARCAYAAYACNGARAAYGGNCCNGGNGGNATHATHCCNGAYGCN MGNTAYGTNYTNACNGARCCNGCNACNGAYACN---------GTNTTYAAYMGNTAYACN TCNAAYTCNAGYGARATHATHCAYYTNAARGARAARGCNGARTAYGTNGARAARATHGAR AGYMGNTTYGARGTNGARACNYTNTCNTAYTCNGGNYTNATHGAYGTNGARTCNGGNATH ACNAARAAYAAYGGNYTNGTNMGNMGNGTNGARCARCAYAARCARATHATHYTNMGNCCN TCNAAYCARCAYGGNCCNTTYCCNTCNGGNAARATHTAYMGNTAYTAYGGNGGNTTYGAR GARMGNAAYGARAAYGGNGAYATHATHGARTTYTGYAGYTAYACNTGYTCNGTNTAYGGN YTNTTYTAY------GGNAAYAAYYTNTCNAGYATGACNYTNTAYAARGTNAAYAAR--- ---AARACNACNCARGARGAYYTNAARATHMGNGGNGGNAARACNATGTCNTAYYTNAAR GCNGARTTYACNCCNTCNGCNTCNGAYCCNTCNCCNGTNMGNTAYACNTTYAARGTNAAR AAYATHAARGGNAAYGTNYTNACNGGNAGYACNATHGTNCAYYTNGGNATHGARATHGAR ATHYTNGCNAAYGARACNAGYATGGARGTNYTNCARAGYGGNACNGCNAAYATHGTNTGY ACNGCNMGNGGNYTNCCNYTNCCNAARGTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATHYTNGGNTCNGCNCCNAARTCNAGYGCNGARATHTAYGCNMGNGARCCN TTYATHTGYCAYGAYGGNCAYGTNTTYYTNGCNGCNGAYTTYCARCARATHGARYTNMGN ATHYTNGCNCAYYTNTCNGAYGAYAARGCNYTNYTNTCNATGTTYTGGACNCCNGGNAGY ACNGAYGTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR TCNYTNAGYMGNGARGARAARYTNGCNYTNYTNACNCARACNTGYGGNGCNATHTCNGAR CAYACNGGNAARATGTGYACNMGNACNGGNMGNTGYGTNCARCAYTCNGAYGARCARMGN AARAAYGTNMGNATHTCNYTNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATHTGYYTNAAYACNCAYGAYYTNGAYGARGARGGNMGNATGCCN GGNTAYTTYGGNTGYCCNMGNCAYAAYGAYACNAAYTCNGAYGTNTTYTGYTGYGGNCCN CARGGNMGNGGNTAYTGYTGY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ACNACNGCNGAY---MGNTCNTTYTCNATHGCNACNACNTGGGAY GGNCARTGYTTYTGYCAYGTNCCNGTNAAYATHTCNYTNGGNCARTCNCCNAGYGGNGAY YTNYTNYTNAARGTNGAYGCNCCNTTYTTYAAYAGYCCNGCNAARCCNAAYGGNCCNGCN GGNCARCCNTTYCCNCARYTNTGGAAYTAYGARGTNGTNGARGCNTTYTTYYTNAAYGAY CARAAYCAYTAYYTNGARGTNGARYTNAGYCCNCAYGGNCARCAYYTNYTNYTNYTNYTN AAYGGNMGNMGNAARATGGTNAARGAYAARYTNCCNYTNCARTTYACNTCNAARATHACN GGNGAYAARTGGAGYGGNGARGCNGTNGTNCCNMGNGAYTAYYTNCCNTCNGCNATHACN AARTTYAAYGCNTAYGCNATHAAYGGNGARGGNGAYGAYMGNCARTAYGARGCNYTNTAY CCNGTNACNGARYTNAAR---------GARGGNATGCARCCNGAYTTYCAYMGNYTNGAR YTNTTYMGNCCNATHGAYATGAGYGCNATHYTNGAYAAYTAYGAYCCNTCNCAYGTNTCN AAYYTNTGG--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR GAYCAYATGGARGAYATHTGYTCNAGYCARYTNYTNGCNTAYATHAARMGNYTNGTNYTN TCNYTNACNGCNCARACNGGNAAYCARGARTTYGCNMGNTTYTTYCAYMGNCARYTNTCN TCNATHYTNCARGAYACNYTNGARAARTAYGARGGNMGNAARATGMGNGARTGYGGNGAR GAYYTNYTNGTNGARATHTCNGAYGTNYTNTTYAAYGARYTNGCNTTYTTYMGNYTNATG GARGAYATHGARGAYCCNAAYGARGTNGARMGNYTNMGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TGGGCNMGNMGNYTNAARAAYAAYTAYGCN GCNAARMGNTCNMGNGAYGCNMGNMGNGTNAARGARAAYCARATHGCNYTNMGNGCNGCN TAYYTNGARAARGARAAYAARTGYYTNAARGARGARATGGCNAARYTNMGNAARGARAAY TCNAARYTNAARACNATHGCNGAYAARTAYGARCCN------------------------ AAYMGNCARGCNTAYATGGAYGCNGTNYTNCARGAYCAYCARCARACNATGTCNGTNATH CCNYTNAGYMGNCAR---CAYAGYTTYAAYTCNYTNGARCAYGTNGAYACNMGNTTYATH ACNCAYAAYAARGCNATHCARMGNATGGGNATHTCNCARAAYMGNAAYMGNMGNGCNCAR TCNGCNMGNGTNMGNACNMGNTCNGCNAARAARGAYGARGTNAARGCNATGGAYATHTCN YTNAARGAYYTNGTNGGNGAYATGCCNTCNAGYAGYCAYTTYGTNGAYACNGARGTNYTN MGNGARCARMGNAAYATHACNCCNTCNCARAAYGGNMGNMGNMGNCCNCARACNTCNCAY ---CCNMGNCAYCCNYTNAAYACNTAYAAYGAYCCNGGNMGNTAYTGYAARGGNGAYGTN TTYGAYGTNMGNGARACNGAYGGNGTNCARAARCCNMGNCCNGTNAGYGCNTCNAGYYTN MGNGAYGCNGAYGCNGCNMGNTCNMGNCCNMGNTCNGGNAARMGNGARAARGGNCCN--- CARGCNCAYGCNTTYATHACNCARAARAAYGARMGNTCNYTNMGNTAYGARTCNACNAAR CCNGTNTAYGTNTTYCCNAARCARACNCCNACNAARCCNMGNMGNAAYTCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGNGARCARTAYMGNCCNATGAARGAYGGNAARGGNAARCCNYTNTGY ATGTAYCARTTYMGNMGNGTNTTYAAYGCNTGYMGNGTNCCNGGNGTNTTYMGNGAYAAR YTNYTNGARTAYTTYAARATHGARTCNGARGGNGARTGYCCNTCNCAYATHATHGTNATG TGYAARGGNCAYATGTTYATGATGAAYACNYTNGAYGAYGCNGGNGARGTNYTNACNYTN YTNGARATHGARGCNCARTTYAARTAYGTNCARCARGARGCNGARAARYTNGGNGCNCCN CARGARGTNAAYTTYYTNACNACNYTNCCNMGNACNGCNTGGGCNGARTAYMGNAAYAAR YTNYTNGCNTGYCAYCCNCAYAAYTAYGAYGTNYTNGARAARATHCARAGYTGYATGAAY ATHTAYGGNYTNGAYGAYGARAAYGCNGTNGAYYTNACNGAYYTNGCNAAYAARACNYTN YTNGGNAAYGTNCARAAYMGNTGGTGYGAYAARTCNYTNTCNATGACNACNTAYAARAAY GGNACNYTNTCNTGYACNGCNGAYCAYTCNTTYTGYGARGGNATHATGATGGTNTTYATH ACNGGNTAYGTNCAYYTNAARGTNAARGARTGYAARGGNGTNTGGCARGGNACNAARGCN GTNMGNCCNCARCCNCCNCCNGTNYTNYTNACNTTYGTNGTNCCNGAYGARGTNATGCAY GGNATHGARATHGCNAARAARGCNTAYAARGARYTNCARAARTGYGCNGAYTGYGTNGTN TTYMGNTAYAARGGNTAYGGNAARGCNTAYTGYAARCARCAYAARYTNCAYCCNGAYGCN TTYTGYCARYTNGCNYTNCAYYTNACNTTYTAYACNYTNCAYGGNMGNATGGCNCCNGCN TAYGARACNGCNGCNATHAARCARTTYTAYCAYGGNMGNACNGARACNYTNMGNTCNTGY ACNATGGARGCNTTYGARTGGTGYCARAGYATGGTNGAYAARTCNTGYTCNAAYGCNAAR MGNTTYCARYTNATGTCNAARGCNATHTCNAARCAYAAYCARAARATGGCNGCNGCNTGY GARYTNMGNGGNTGYGAYMGNCAYYTNATGGGNYTNGCNYTNATHGCNAARGARGARAAY ATGCCNATGCCNYTNYTNTAYCARGAYCCNTCNTTYGTNAARAGYGGNGGNGGNGGNAAY TTYYTNYTNTCNACNAGYACNGTNGGNTAYTCNAGYATHATHGGNGGNGTNYTNCCNATG TGYGARAAYTGYTAYGGNTGYTTYTAYMGNATHAAYGAYAAYATGYTNACNTTYTTYATH TCNACNTGGAAYGCNGAYAARYTNACNAGYAGYMGNGGNTTYGARGARGCNYTNGGNAAR AGYYTNGAYAARATGAARGARGTNATHGAYCARGCNACNAGYGCNGCNAARGCNMGNYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNATHYTNACNTGYGGNGGNACNATHGAYAARCARTAYCCN CARGGNCCNGGNGCNTAYGCNTTYGARTTYGGNGAYGCNGCNATHGARAARATHYTNCAR MGNATHMGNCCNTCNTTYCARTAYCARATHGARAGYATHTGYACNAARGAYAGYCARGAR ATGACNGAYAAYGAYMGNGARGAYATHYTNMGNGCNGTNGTNGAYGGNGAYCARAGYYTN ATHYTNATHACNCAYGGNACNGAYACNYTNTGYGAYACNGCNCAYTAYYTNAGYAARGCN GGNGTNGGNCARGGNCCNCARTTYGGNCCNGGNGTNGGNGARAARACNGTNATHYTNACN GGNGCNTTYAARCCNGARACNATGAARGAYTCNGAYGCNGAYTTYAAYGTNGGNTTYGCN YTNGGNTTYYTNCAY---TCNTCNACNCCNGGNGTNTTYGTNGCNATGGARGGNAGYATH YTNGAYGGNAGYCAYGTNATHMGNTGYGARGAYGGNAARTTYGTNGAYGARMGNTTYGTN YTNAARMGNTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNGTNAARTAYGGNGAYYTNTGYAARAAYATGAARTCNAAYATHMGNGGNAAY YTNACNGCNTGGGARMGNGARAARAARCARATHAARCARYTNGARAARGCNCARYTNAAR CARGCNCCNAAYAGYCCNCARGTNATHAARGCNCARAGYGAYYTNATHYTNMGNGARTTY GTNCARATHGARATGYTNTTYCAYTCNAARGCNGAYATGGAYCARTTYMGNAGYGCNYTN YTNGARGCNTCNGGNYTNGCNMGNTCNTTYACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGYTNTCNMGNTCNGGNMGNGCNGARACNMGNAGYMGNGCNAARGAR GAYATHAARMGNGTNATHAAYGCNATHGAYAARGTNMGNAARTGGGARAARAARTGGGTN ACNYTNGGNGAYACNTCNGTNACNATHYTNAARTGGGTNCCNGTNACNGCNCARGARAAY CCNGGNGCNYTNMGNAARATHCCNGGNGTNAARACNAARACNTAYTCNAARGCNMGNGTN GARMGNGARMGNGARYTNTAYAAYGCNGARACNAAYGGNYTNCCNMGNGCNAAYTCNCCN GCNGAYTCNACNAGYAAYAAYACNAAYATGTCNAAYACNAGYTCNCCNTCNTCNAARAAY CAY------AAYACNGARAARGCNAARAAYGGNAAYGTNACNAAYAGYCARAAYTCNGTN GTNTAYTCNGARGARAAYACNCARCARTCNACNGGNTCNTTYGGNTCNGARATGYTNAAY GARGAYTCNAAYATGTCNTTYCCNGARAAYAGYGGNYTNAGYGARCARGGNGAYCAYAAY GARTTYTCNCAYGAYAGYAAYGAYGCNGAYCCNGGNATGMGNGTNGCNATGAGYATGGTN GGNGAYGARGARGCNGCNAARACNGAYCARGGNCAYGAYTCNAAYGARTCNTCNCCNCCN GARCAYGARAARGAYTCNTCNTCNGARGARCCNCARGARAARAARGCNAARACN------ ATGTCNGARAARCAYAAYTTYGGNGTNGCNCCNGTNACNTGYCAYGCNTTYAGYAARGAY MGNAAYGGNYTNGCNATGTCNYTNAAYGAYTCNAAYGTNAARATHTAYAARAARTCNGGN TCNAARTGGGAYGARGCNGAYACNYTNAGYGARCAYGGNCARMGNGTNACNAGYATHGAY TGGGCNCCNAAYAGYAAYMGNATHGTNACNTGYTCNGCNGAYMGNAAYGCNTTYGTNTGG ATGYTNGARGAYGGNAARTGGAARCARGTNYTNGTNATHCCNMGNATHAAYMGNGCNGCN ACNTGYGTNAARTGGTCNCCNAARGARAAYAARTTYGCNGTNGGNAGYGGNTCNMGNYTN ATHGCNATHTGYTAYTAYGAYGAYGARAAYAAYTGGTGGGTNAGYMGNCAYATHAARAAR CCNATHMGNTCNACNGTNACNTGYYTNGAYTGGCAYCCNAAYAAYGTNYTNYTNGCNGCN GGNTCNACNGAYTTYAARTGYMGNGTNTTYTCNGCNTAYCARAARGARGTNGAYGARAAR CCNGGNCCNTGYAGYTGGGGNACNAARATGCCNTTYGGNGCNYTNATGGCNGARTTYAGY AAYGGNGGNGGNGGNTGGGTNCAYTCNGTNTCNTTYTCNCCNAAYGGNACNYTNGCNGCN TGGGTNGGNCAYGAYTCNAGYGTNTCNATHGTNGAYTCNTCNAARGGNAAYGARYTNACN GTNATHAARGAYAGYTTYYTNCCNTTYATGAGYYTNACNTGGATHACNGARAAYTCNYTN GTNGCNGCNGGNTAYGAYTGYAAYCCNATGGTNTTYTCNTTYGGNGGNGGNAARATHACN TGYCARGGNAARYTNGAYGTNCCNCARGARAARGCNTCNGGNACNATGAGYGCNATGAAY MGNTTYAARAAYYTNGAYAARAARGCNACNGAYAGYGARAGYTCNAAYGARATGAARACN CARCAYCARAAYACNATHACNAAYGTNTCNATHCAYACNGGNGAYAARCARAAYGCNAGY AARATHGCNACNAGYGGNGTNGAYGGNAAYYTNATHATHTGGGAYYTNAAR--------- ------------------------------AARATHGARACNGTNAARACNGARTGGAAY GCNAARCCNMGNATHGGNTCNYTNGARAARGCNCAYCAYAARCCNGGNGGNGGNGAYGTN AARATHGARACNGTNAARACNGAYTGGAGYGCNGARTCNAARATHGGNTCNYTNAAYAAY GTNAARCAYAARCCNGGNGGNGGNGAYGTNCARATHGARACNCAYCARYTNGAY------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TGYGAYYTNTGYCCNTGYCCNAGYYTN ACNGCNTAYTGGACNAAYCCNCCNTCNTGYCCNMGNMGNGTNTGYTGYGARAGYAARTCN TCNTGYTGYTCNTTYAGYTGYTTYMGNGAYAGYMGNACNGTNTCNGTNTTYGTNGCNACN GTNATHATHACNTAYTTYATHTTYATGGAYATHATHYTNTAYTGYTAYTAYATGAARGCN AAYYTNGTNGARGAYTCNAARGGNGGNAGYGCNGARGARATHTAYACNCCNTTYACNCAY YTNTCNGTNAARGCNYTNYTNAAYGAYCARCCNAGYCARTAYYTNATHGCNCCNAGYACN GARTGGYTNGARTAYTTYACNAAYTTYGCNAAYACNTTYTAYTTYATHACNCCNAAYGTN GTNTCNTTYACNCAYYTNATHGTNGGNTTYATHTCNGGNAARTTYATHTCNTCNGAYAAY YTNAAYGAYMGNMGNATHGGNGTNTTYYTNTTYGARTTYMGNACNTGGYTNGAYGCNTTY GAYGGNACNATHTTYMGNGCNCARCCNGGNAAYCAYYTNAARTAYAAYTCNGTNCAYAAY ACNYTNGGNTAYTAYATHGAYTCNGTNTTYGAYAGYGTNGGNGGNGCNTTYYTNTGYTTY GGNATHYTNTTYTAYYTNYTNAARAARTTYGGNCCNCCNMGNTTYCARTGYGTNYTNCCN TTYTGGTCNTCNGGNTCNTCNGAYGGNAAYAARGTNCCNYTNGTNAGYGARGGNAAY--- ---------AARGARAGYTAYTCNTCNYTNTAYYTNTTYTGGAARGTNTTYTCNTTYGGN ATGGTNYTNYTNGTNTCNGCNGGNGCNTGGGAYAAYATHGTNGTNCARTTYTCNGARGTN TTYCARACNGARYTNAARGAYCCNAARYTNGCNGCNYTNCARYTNGARYTNTCNCAYTCN AAYACNACNGTNTTYATHTTYCARYTNTGGMGNYTNATHGGNTCNCARTGYATGYTNAAY TAYATHYTNATHGTNATHTTYTGYGAYAARATHTGGGARTTYYTNAARGGNACNCARTAY ATHYTNATGGTNATGATHGTNAGYYTNTAYATHATHTCNACNYTNTAYGTNAAYATGATH MGNACNCARYTNCAYYTNCCNAARYTNATHGTNTTYGAYYTNGAYTAYACNYTNTGGCCN TTYTGGGTNGAYACNCAYGTNAGYCCNCCNTTYAAYAARGCNCARGAYGGNAARATHMGN GAYGCNMGNAAYAGYCAYGTNACNTTYTAYCCNGAYGTNCCNGARATHYTNGCNMGNYTN CAYGCNGAYGGNTAYGCNYTNGGNATHGCNTCNMGNACNGGNGCNATHAARGAYGCNGAR GAYYTNGTNAGYYTNTTYGGNTGGGAYCARTAYTTYAGYTAYMGNCARATHTTYCCNGGN TGYAARATHACNCAYTTYAARGCNYTNCARAARATGAGYAARGTNCCNTAYAARGAYATG YTNTTYTTYGAYGAYGARCAYMGNAAYATHAARGAYGTNTCNTCNYTNGGNGTNACNTGY ATGTTYGTNCCNGAYGARGGNGTNTCNMGNGCNTCNYTNCARGARGGNYTNGARYTNTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY TCNATHCCNGARGAYMGNAGYCAYGAYCCNTCNCCNTCNAARYTNAARGCNCARTCNAAY CCNCARAARGGNAARGGNACNMGNCARGCNCAYGTNATHGAYCCNAAYATGTTYAARYTN MGNGARMGNATHGCNAARCARAARACNAARGTNGAYAARGAYATGYTNAARGARATGMGN MGNATHGARAARYTNAARAARYTNGARAGYYTNYTNAGYTCNAARAARTCNGGNAARATG TCNTCNGARAAYGAYATHCCNMGNYTNAARAARCARGAYGCNMGNGARTCNGTNGCNTGG CAYATHCCNATHGAYYTNCCNTCNAAYCARTGGAARGARCCNTCNATGGARCAYAARAAR CARCCNCARCCNYTNACNTCNYTNGTNACNAAYAARCAYAAYAARAAYGAYAARCAYTCN GARTCNYTNTAYAAYAAYAARAGYGARTAYAAYAAYGARATGAAYAGYATHTGGACNAAR AGYAGYCAYCCNMGNGGNATHCCNAARYTNCARTGGGARMGNGTNGTNTCNAARGAYGCN YTNGCNAGYAARACNAAYCAYTGGGARGTNGAYCCNATGATGGAYMGNGTNCARTAYATH YTNAAYAARCCNGGNACNGGNAAYACNTAYCAYAAYCARMGNGAYGGNAGYGARGARAAR CCNYTNTCNAARATGTCNYTNCARGARGCNTTYTTYATGMGNAARCARMGNTTYATHTCN AARTGYTCNGARMGNCARAARMGNYTNAARYTNGCNAARGAYGAYMGNCARYTNCARGAR TGYYTNMGNYTNGARMGNGARGCNATHTTYGTNGARCARCARMGNYTNGCNCCNCCNAAY YTNTAYGCNCAYCCNTAYAGYGAYAAYYTNCAYCARCCNAARCAYMGNATHYTNACNAAR CARGARATGAARACNYTNACNGCNMGNMGNTAYAAYAARYTNCCNGARGTNGTNGGNAAR AARGARGAYGAYAARAARAARATHGARGCNAARYTNAAYMGNYTNMGNGCNAGYYTNTTY AAYAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CARTGGTGYTCNGCNATHAAYTGY TCNAAYAAYMGNYTNMGNCARCCNAAYYTNTCNTTYTTYMGNYTNCCNTCNGAYCCNGAR MGNGGNAARAARTGGATHATHAAYGCNCARMGNTTYGAYYTNYTNGARAARCCNTAYAAR AARYTNCAY------AAYATGTTYTGYYTNGARCAYTTYGARCARMGNTGYATHATGCCN AAY---------TTYMGNMGNCAYYTNTAYAARTGGGCNGTNCCNACNGTNTTYAAYTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGYTNYTNTAY CARTGYGTNATHTCNGGNGAYGARATGTTYACNGAYACNTAYAAYATHGARGARAARGAY GGNTTYTTYATHATHAARGGNAARTTYATHACNAARAAR---ACNGAYGAYGTNGAYGCN TCNYTNYTNGGNGCNAAYCCNAGYGCNGARGAYTGYGGNGAY---GARGTNGARGGNGGN GTNGARTCNGGNGTNGAYGTNGTNYTNAAYAAYMGNYTNAARGTNACNGGNTTYGGNGCN AARAARGARTAYCARYTNTAYATGAARGAYTAYATGAARGCNGTNTTYGCNAARYTNGCN GAYAARGGNATGTCNGCNGAYGTNGCNGCNTCNAARGCNCARGCNACNGARGCNTTYAAR GTNGCNTGYGGNAARTTYAARGAYYTNGARTTYTAYACNGGNGARAGYCARAAYCCNGAY GGNCAYATHGCNYTNATHGARTGGGTNGAYGARGARGTNGAYGGNGARTCNGTNTCNACN CCNTAYTGYTAYTTYTAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTNTGGAAYGCNGTNYTN--- ------CCNGAYGTNCARTCNATGMGN---------ATHGTNGGNMGNTGYTCNYTNYTN TGYGCNGARGARMGNMGNGCNAARTCNGARTGYGTNAARCARMGNGAYTGYTTYTCNTTY ATGTTYAGYGAYAAYYTNGARAARTTYGCNCARTGYGCNGARCCNTGYTCNAARATH--- GGNGAYTGYTTYGARMGNTGYGCNYTNGGNGCNGAYGARATHAARCARAARTGYGCNTCN CARTGY------------------------------------------------------ ------------------------------------------------------------ ------------------------------GARGAYACNGCNGAYGCNAGYGARACNGAR GAYAARACN---CCNAARTCNCARAARCCNAGYGCNAAY---GGNAGYCARMGNACNGAR ATHAARGARCARATGTAYCARGAYAARYTNGCNCARATHAARAARCAYATHCARATGYTN GARGARGGNACNYTNCARGARTTYYTNAARMGNACNAARAARATHGARYTNAAYTAYMGN GARMGNYTNMGNGAYAAYGARATHTGYAARAARGTNGAYATHGARAARGCNGARCARAAY TAYYTNATHGAYTGYGAYAAYGCNCARAARGARTTYGARGARAARMGNGTNGCNATGAAR GARMGNYTNATHAAYCAYYTNAARGARAARAARATHGAYYTNAARGARACNYTNATHAGY GAYYTNAARGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TCNYTNGGNMGNACNGAYTAYCCN TCNGGNATGAARCARATHGTNYTNAGYTTYTTYACNAARYTNYTNTCNMGNYTNTCNCAY CCNYTNYTNCCNCAYATHAAYGTNCAYAARGCNGTNCARMGNATGGTNAARACNTGYGGN GARACNMGNGCN------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTCNMGNGCNGCNCARTCNAARACN MGNGGNGCNGAYAARACNAARCCNCCNGCNTCNCARACNCCNGTNATHGCNCAYGARATH GTNCCNGGNAARTTYAAYGAYAAYGAYTGGAAYTCNATGYTNGARMGNGAYGGNGGNGAY GARTTYGTNATGGAYATHATGGAYACNYTNATGGARAARACNATGYTNACNATHTAYGAY AARTAYATHGARMGNCARYTNYTNCCNTTYACNATHACNCARGCNMGNGAYGCNATHATH GARATHATHGARTGGCARTTYYTNACNMGNGAYGARGGNGARGARAAYATHGARGCNGAY YTNGGNTGGACNCARGAYGARGARCCNGARCCNGCNGARACNGAYTGYTGGGCNCARGGN TCNGTNCCNMGNAAYATHATHYTNGCNCCNACNCCNGARYTNGARGARATHCCNGARGAR GCNGARGARGTNTCNCAR---------------GARGCNGARGARGARAARGARTGYGGN GARGARGCNAGYCARGARCCNYTNGARYTNGARGAYGTNGTNTCNGARTCNGARGAY--- ------GCNGGNGTNACNAARGARGAYAARGAYATHGARAARACNCCN------TCNCCN CCNAARGTNTCNYTNTCNGGNTCNAARAARAARTAYMGNCCNTAYMGNGGNAARYTNAAR TCNGCNGGNGTNMGNAARATGACNGARTCNYTNGARGAYACNGARATHAARATGATHTAY GAYGARATHGTNGCNTCNATGCCNCCNAGYGARGARAARCCNAGYACNYTNYTNAAYATG CCNGCNTCNTGYACNAGYATHYTNAARGTNCARACNGGNMGNCCNCCNGGNAAYAARGAY GTNGTNTAYGAYGARYTNGGNAAYGTNGTNGCNGTNATGMGNYTNGAYCCNGARAARYTN CCNACNCAYAARGTNAAYGTNAARTAYCAYGTNGTNGAYCCNGCNGTNGARGCNGCNCAR GCNMGNYTNGAYGCNATGMGNAARGGNAARTCNACNGGNAGYAARATGMGNAARATGMGN TCNAAYMGNAGYYTNGCNTCNGARAAYGTNGCNGGNACNTCNAARACNAARACNACNCCN CCNGCNAAYACNGTNGCNCCNYTNCCNCCNCCNYTN------------------------ ---------------------------------ATHGARGARATGGARGTNTCNCAYGGN GTNATHATHAARGARGGNGGNMGNGTNAARAARGGNCCNGGNMGNTAYTAYMGNAARYTN GAYGTNYTNGARGARCAYCARAARGGNATGAARCCNGTNACNGTNMGNYTNAARAAYGCN GGNATHACNGTNAAYGAYYTNYTNGAYMGNAAYACNCCNATHYTNMGNCCNYTNACNGAR CARTCNCCNYTNCCNCCNATHGTNCCNCARCCNYTNCCNMGNGCNGAR---CARTCNAGY ATGGTNAAYGTNGCNGTNATHGGNGCNGGNATHATHGGNYTNAGYACNGCNGTNAAYGCN CARMGNGTNYTNCCNTCNGCNAARGTNACNATHYTNGCNGAYCARATHTTYAAYGAYGGN GTNAGYGARGGNGCNGGNGGNYTNTTYMGNCCNGARYTNAGYAARATHGTNCARGGNGAY AAYGGNCCNYTNATHAARCARTGYYTNMGNGAYTCNTGGGAYCAYTTYACNAGYYTNGCN GTNTCNGARCAYGCNAARGARTCNGGNCARTTYATGGTNTTYGGNYTNGCNTCNCAYMGN MGNAAYATGGAYGARGAYTAYACNTTYATGMGNGARTGYACNTAYGAYTTYMGNMGNYTN TCNGAYAGYGARATHMGNCAYMGNGGNATHCCNGARGARTTYAARTAYACNTAYGCNTTY ACNTCNGTNGTNTCNCARGCNACNYTNTAYYTNCCNTGGYTNATGMGNCARTTYGARGCN CARGGNGGNACNYTNGTNAARMGNACNGTNAAYAARYTNGARGARYTNTAYGGNGARTAY CARGTNGTNATHAAYTGYTGYGGNCAYMGNGCNYTNACNTTYATHGGNGAYGARGARTGY TTYCCNACNMGNGGNCARYTNGTNMGNGTNAARGCNCCNTGGTTYAARCAYTTYCAYTAY TTYGAYACNGAYTCNTAYATGATHCCNCAYGTNGAYAARYTNAAYATHGGNGGNATHMGN ATHCAYGGNGAYCCNAARACNGARGTNGAYCCNGCNGTNTCNGAYACNATHATGMGNGAR GCNGARGCNATGTAYCCNMGNYTNAARGGNGCNGARMGNGTNGGNGTNTGGGCNCAYTCN MGNCCNGGNMGNAAYMGNCCNMGNATGGARACNGARACNYTNCARYTNGGNGGNAAYMGN AARYTNGTNGTNGTNCAYAAYTAYGGNCAYGGNGGNAAYGGNGTNACNYTNAGYTGGGGN TCNGGNAARTAYGCNGCNAAYYTNGCNAARCARTCNYTN---ATGGARGAYGARGARTGG CCNGCNCCNGGNTCNCCNCCNYTNCCNAARAARGGNGCNTAYAAYATHGAYTTYGAYAAY YTNGAYGARTTYTCNAAYCCNTTYGARTCNAARAGYAARATGATGATGGGNTCNTCNCCN CCNATHCAR---------------CCNAGYACNGTNAGYTTYGAYGARAAYGCNGAYCCN TTYAARTCNAARAARTGYATHGCNAAYTCNCCNCCNGGNTCNCCNAARGTNGTNCCNAAR AAY---MGNGARCCNATHGTNAARCCNGAYCCNGTNGGNGAYGGNYTNAAYAGYGAYGGN AAYGARACNGTNCCNYTNCCNCCNGCNGARGCN---TCNGTNGARGARGARAARAGYGTN AAYGTNACNCCNAARAARAARAARATHATHAARAARCCNCARGCNCARTCNAARTTYAAR CCNCCNMGNGAYYTNAARMGNAAYAARAAYAAYGAYGAYATHGARATHCAYATGCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARATHYTNAARGCNATHMGNYTNGAYGGNATHGAY ATHMGNGGNTAYACNGCNTGGTCNYTNATGGAYAAYYTNGARTGGACNAGYGGNTAYTAY TCNAARTTYGGNYTNTAYMGNGTNGAYTTYGAYCAYCCNAAYMGNACNMGNACNCCNMGN ACNTCNGAYGTNTTYTAYAARCARYTNATHCARAAYCAYGGNTTYAAYAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CAYAARTGYTTYCAYTGYGGNAARATGTTYAAYTCNAARTCNAAYYTNAARTCN CAYATHMGNACNCAYACNGGNGARAARCCNTTYGARTGYAGYACNTGYGGNMGNGCNTTY TCNCAYAARTCNGAYYTNAAYMGNCAYGTNMGNACNCAYTCNAAYGARMGNCCNTTYGGN TGYGAYATGTGYYTNAARAARTTYGTNACNAARTGYGARYTNACNMGNCAYATHACNATH CAYACNGGNGARGAYCCNTTYGARTGYAGYAARTGYGGNMGNTCNTTY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GGNAARTTYGARAARYTNGAYGARYTNYTNCCNGAYATGAARGARMGNGGNGAY MGNGTNYTNYTNTTYAGYCARTTYACNATGATGYTNGAYGTNGCNGARCAYTAYYTNGAR CARMGNCARCAYAARTTYATHMGNYTNGAYGGNCARACNCCNGTNCCNGAYMGNYTNCAR YTNATHGAYMGNTTYAAYAAYGARCCNGAYATHTTYATHTTYYTNYTNTCNACNMGNGCN GGNGGNYTNGGNATHAAYYTNGTNACNGCNAAYACNATHATHYTNCAYGAYATHGAYTTY AAYCCNTAYAAYGAYAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNYTNTCNATGCCNAAYGTNGCNATGAAYGGNGTNYTNMGNAARMGNGCNYTNATGAAY AARATHATHGCNAAR------AAYTGGCCNMGNGARTAYGTNATHGTNGCNGAYCARTGY YTNTAYTAYTAYTCNAGYGARACNGGNAARAARCCNTCNGGNGCNTTYTCNYTNTAYGGN TTYAAYMGNATHTGYMGNGCNCCNCARACNAARGCNAARGAYACNGTNTGGGCNTTYAAR YTNGARCAYATHCARCCNAAYGTNCARTCNYTNTAYTTYTCNGCNCCNTCNGARAARGAR ATGMGNCARTGGATGAGYTGYATHAARCARCARATGYTNYTNGCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TGYGTNMGNCARTAYYTNMGNTGYGARGAYTCNGTNTGGAAYMGNGCNATHTGY GTNGGNGGNTAYTTYAGYCAYACNATGAARGARTGYGTNCCNTCNGAYGAYCAYTGYGAR ACNMGNCAYMGNMGNCARACNACNACNAGYTGYAGYGARGCNTAYAAYTGYCCNAARGAY YTNATHCARGARTTYATHTAYCCNGAYTGGAARGAYTGYGAYACNTAYTTYAARTGYYTN MGNGGNGTNYTNAAYAARCAYACNTGYAARAGYGGNATHTAYAARTAYTAYAAYCCNMGN ACNTTYAGYTGYGARGARTAYCCNTCNACNACNAAYACNTGYYTNAARMGNTAYGARACN ------------------------------------------------------------ ------------------------------------------ATGGCNGAYTCNAARTCN AGYYTNGCNMGNGAYGGNACNATGCARGTNACNGCNAARGARGGNATHGAYTAYYTNAAR GCNGCNAAYAARGAYACNYTNYTNAARGCNCARGGNYTNGTNAARGAYAARCCNGTNGTN CARMGNGAYGGNACNATGGTNGCNACNGCNAARGARGCNGAYMGNYTNYTNGAYGGNAAY AARCCNGAYGCNGAYGCNCARACNMGNGGNCARCARAARCARATHGAYGAYYTNAARAAY GAR---ACN---CCNAARGCNAARAARGCNMGNYTNGCNAARGAYGGNACNATGGCNGTN ACNGCNAARGARGCNAARGCNYTNYTNGGNAGYGARAARYTNGGNGAYACNMGNCARGAR ACNAARAGYAARTCNGGN------AARACNCCNYTNAARAARACNAAYACNATGGCNMGN ACNGTNGARGARGCNAARAGYGTNYTNAAYGGNAARGTNGAYYTNAGYGARGGNMGNAAR ACNMGNTCNCARAGYMGNGGNGAYCCNCCNAARCCNTCNATHAARAARATGGGNACNATG CARCARACNGCNAARGAYGGNAARGCNTAYYTNAARAARTCNAARGGNAARAAR------ ---MGNGCNGCNAARACNGAYGAYGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGCCNAGYYTNCCN YTN---------------------ACNAARCAYACNATGGCNGCNGCNGGNGCNAAYACN GCN------------MGNGCNATHAARCCNCAYGTNCCNYTNATHAARTTYCCNAARMGN GAYCCNYTNACN------------GARGCNMGNCCNATHGGNAAYCCNAAYTCNATHGAY ACNYTNYTNACNAARAAYGTNACNTCNMGNCCNGCNCCNGCNTCNAGYGGNTCNTCNAAR GCNAARGGNCCNTCNGTNGARTAYTCNGARYTNCCNGTNMGNTAYMGNMGNAARGCNYTN TCNGCNGARGARATGGARTAYATHGARAARGGNGGNCARGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TGGAAYMGNGAYGTNAARGGNMGNATHTCNAGYCCNGAYATHCCNTTYACNMGNTGG GAYACNGAYMGNATHACNGCNTGGYTNAAYGAYATHGGNYTNAAYATGTAYYTNGTNGAY TGYAARMGNTGGGTNMGNAAYGGNGARCARYTNYTNMGNTGYTCNCARCARGAYYTNGAR AARGARYTNGGNATGAARAAYAGYYTNCAYMGNAARAARYTNACNATGGCNATGCARGCN GCNTCNACNGCNMGNCCNGAYYTNATGGGNGAYYTNGAYCAYAAYTTYGTNGCNMGNTGG YTNGAYGAYATHGGNYTNCCNCARTAYAARGAYTCNTTYTAYGAYGCNMGNGTNGAYGCN MGNATGYTNAAYAGYYTNACNGTNGARGAYYTNTTYAAYYTNAARGTNTCNAAYGARGTN CAYCAYGTNTCNATHMGNMGNGGNATHCARGCNYTNMGNYTNAAYAAYTTYGAYCCNAAY GCNYTNMGNMGNMGNCCNGCNCCNGARGARCCNAARCAYATGGAYTCNATHCCNGGNGAR GTNGTNYTNTGGACNAAYCAYMGNGTNATGGARTGGYTNMGNACNATHGAYYTNTCNGAR TAYGCNCCNAAYYTNMGNGGNAGYGGNGTNCAYGGNGCNYTNATGGTNYTNGARCCNMGN TTYAAYTCNGARYTNTTYGCNGTNYTNYTNTCNATHCCNGCNAGYAARACNYTNYTNMGN MGNCAYYTNAAYTCNCAYTTYATHGGNYTNATHGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATHCAYACNCARGTNTCNCCNYTNYTNTTY CARGTNTCNGARAARYTNTGGGGNATGCCNATGAARAARAARAARGGNYTNGAYCCNCAR YTNGCNGTNGCNMGNTCNGARAARMGNATHAARAARATHGAYAARGARATHAARMGNYTN TCNMGNATGGGNAARATHYTNAARCCNATHGARGARATHGARGGNGAYMGNAARMGNYTN ATGGCNTCNGAYGCNMGNMGNMGNGARCCNACNGTNYTNAGYTTYGARGARTCNGARGAR MGNGCNYTNYTNCAYAARGCNTGGTCNGTNTTYMGNACNAAYMGNTAYAAYGARATGGCN ACNGCNTAYTCNAARGTNGTNTCNGCNCARCARGARGCNYTNGAYGARYTNMGNGCNGAR TCNGARGARYTNTAYYTNGCNGCNATHCARAARGAYGARAGYYTNYTNCCNYTNACNTTY GAYGGNCCNAARGARACNCCNCCNATHAARAAYTAYGCNCCNCCNGAYGGNGARTAYATH GAYACNACNMGNAARTAY---------AGYGGNGAYATGGARTGGAAYATHGAYATGGAR GTNAAYYTNTTYCAYGCNATGMGNGGNCAYAARCCNGCNGGNGTNAAYMGNCAYTTYCAR ATGATHGCNATHCAYGAYAARYTNAGYTCNTCNACNAARAARYTNTCNTCNAGYGAYGTN TGGAARCAYYTNTCNACNYTNTAYGAYYTNCARGCNYTNTAYGARTCNGARATHGTNCCN TTYCCNAAYAARAAYGGNGAYTTYGCNYTNGTNGAYAARGAYATGYTNGAYYTNTGYACN AARTCNTTYCCNMGNTCNTCNTAYATHAAYACN---CCNGTNGARCCNGCNAARACNGAR CCNACNGGNAARTCNATHCCNAARYTNAGYTCNAARCARGAYGGNAARATGGGNTCNCAR ACNCCNAARTCNGAY------AARAAYGARCARAARCCNTCNAGYGCNYTNAARGCNGAY AGYMGNYTNAAYACNCCNTCNAGYMGNTCNGARTCNAARTCNTCNAGY------------ ------------AGYAGYATHTCNAARTCNTCNTAYYTNAGYACNCCNACNTCNGCNCCN TCNCCNTCNCCNAARMGNGCNAARMGNACNMGNAAYGTNAAYTCNACNTCNGCNAGYCCN GCNACNCCNACNGARCCNCARTCNAARMGNMGNMGNATGAARGARGARTAYTGYGGNACN CCNGTNTAYATGGCNCCNGARATGAAYTCNACNTAYTCNTAYYTNGTNGAYGTNTGGGCN ATGGGNATHATHATGTAYTAYYTNYTNACNGARTAYCCNAARGAYAAYYTNYTNAAYGAR TCNATHAARACNGAYGGNCCNCARTTYAARGARCCNCARTGGATHGCNGTNAGYGAYCAR GCNAARGAYYTNYTNMGNGARATHYTNACNCARGAYCCNGCNCAYMGNCCNTCNTCNGGN GARGTNYTNAAYCAYGARTGGTTYACNGGNAARAARMGNGARCAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TAYCARYTNCARGAR YTNTCNGTNATGTCNAARGCNGTNGARGTNGARMGNGAYAARATGACNGARYTNGTNCAR GTNYTNCARACNMGNYTNTCNGARGARGTNGAYMGNCAYAAYAARACNCARCARGARYTN CARGCNCARAARMGNTCNGGNATHGARYTNGARAARYTNYTNGGNMGNAARAAYATGGAR GCNTCNMGNGGNGGNGTNGARGCNAARAGYYTNGAYGCNGCNAARACNGAYGAYGAYTCN GAYGAYGARGGNGGNAAYTCNAGYAARGCNGARYTNGTNACNMGNYTNGARATHCARAAR GAYGARATHCARTCNYTNAARYTNACNYTNCARMGNAGYATGAARGCNAARGARGAYGAY YTNAARGTNTAYAGYAARACNYTNGAYGARACNAARCARGTNTTYYTNCARGCNYTNMGN CARATGAARGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TGYCARTCNYTN GCNYTNCCNTAYTAYTCNGAYTTYTGYYTNCCNGTNGGNGTNGAYAARGAYCARGAYGAR TTYACNGTNAAYAARGGNTGGATHGCNGGNGCNTTYTTYYTNGGNYTNYTNYTNGGNGTN GGNATHGTNYTNYTNYTNGCNMGNCCNTTYYTNAARGCNTGGGARAARAARAARCARCAR GAYGARGARTAYATGYTNGAR------------AARACNGTNAARGCNGARCARGCNGAR CCNTTYCCNGAYAARAARGARGGNAAR---------------GTNGARGARAARGARAAR AARGGNMGNMGNAARTCNAARTCNMGNTTYTGGMGNMGNAARCCNAARGGNGGNGGNAAR GAYGARACNGTNAARGARGGNGAYGTNGAYCCNGCNCAYGCNMGNGGNATGGTNGAYGTN ATGYTNCARACNACNAGYACNGGNGARGARGTNGARYTNGCNGAYCARGAYATGGCNGCN ATHATHTCNATGGARMGNGGNYTNGARGARGARAARACNACNYTNATGYTNAARACNYTN GCNATHYTNYTNMGNAARAARGCNGARAARMGNGARATHACNCARAAYTTYTAYACNGAY TTYATGAARAARGCNGARGARGAYYTNAARGAYATGGGNACNATGATHGAYMGNGARAAR GARGARGCNGARGARAARYTNAARAAYGAYCCNAARYTNAAYAARGAYACNCARACNATG GARACNGARATGCARAARYTNCARACNCARTTYAAYCAYAARCARGCNAARYTNCARAAR GAYTTYMGNGAYAARATHMGNYTNGAYYTNYTNMGNTCNTCNGGNATGCCNGARTCNGAY GTNGARGAYGTNATHTCNGGNYTNATGGCNAAYATGGCNCAYGTNGARGARAARYTNGGN YTNGARCARGCNMGNCARMGNMGNTCNTTYGARCARMGNYTNGCNAARMGNMGNCARGCN ATHGARTAYCARGARATHGARAARGAYGARAARATHAARGARCARGARGCNAARATHAAR GTNTTYMGNTCNYTNYTNGARCAYCAYACNAARGAYGGNTCNYTNYTNGARAARCARTGY GAYACNATHGTNACNGAYTAYGARAAYGARYTNGAYCARYTNMGNAARTAYCAYGCNGAY GGNTAYAAYCARYTNMGNYTNGARAARTTYGAYCARYTNCARCARGAYMGNYTNAAYAAY TTYTAYAARYTNAAYAARAARCAYGAYAARGARAARGCNGCNYTNYTNCAYAAYGCNGAY AARGCNACNAAYTCNGCNGARTTYGTNAARYTNTAYCAYGAYYTNATGACNAARCARCAY ATGGARAARGARGCNYTNTCNGGNGARYTNGAYATGMGNGARATHCARGARATHCAYAAR YTNACNGARGAYTGYAARAARAARGARGARAARGCNATGGCNCARGCNACNGAYAARYTN GCNGARCARATHGARGGNTCNTCNAAYATHACNTCNAARGARGCNGCNAARATHATGAAR YTNCAYAARGCNGARATGGAYCARTAYMGNGCNAARAARCARMGNGARAARCARGCNATG YTNGCNMGNYTNCARGARAARYTNCAYCARMGNATHGARGCNGCNGAYGARGCNGARGCN MGNGAYCARAARGARCARGARGCNYTNAARGARCARCARATGGCNACNYTNAAYAARGTN YTNGCNACNAAYYTNGAYYTNTCNGARGAYGCNAARGAYMGNATHATGMGNGARCAYGAR CARAAYATGCARACNYTNTCNAAYCARYTNATGMGNAGYAARATHMGNCARCARAARAGY YTNGARATHAARYTNAAYCARAARAARGCNAARYTNGCNGARYTNAARCARAARMGNGAR GAYGCNYTNCCNGAYAGYAGYAARAARGARAARGCNAAYYTNGARAAY------ATGGCN ACNAGYYTNGAYGARCARATHGCNAARGARGARGCNGGNTTYGARGAYGCNMGNCARGTN GCNGTNGCNGARYTNMGNAARCARYTNGCNCARGARACNGARGARGCNYTNAARCARCAR GAYGARGARATHGGNYTNYTNATHGGNMGNYTNCARGTNGGNCARGCNMGNMGNAARGCN ATHYTNGARAARCARGAYGCNGTNYTNAARGAYYTNCARGAYAAYYTNGARMGNCARGTN TCNTCNGCNAGYGGNYTNAARCCNTCNATGACNGAYCARATHYTNAAYCAYCAYTAYGCN AARGTNTCNAGYYTNAAYGAYCARYTNCARMGNCAYMGNGAYGAYCAYGARMGNMGNATH YTNGARAARYTNTCNCARAARMGNGCNGARAARGARTAYCARATHGARTCNCARYTNGAR MGNGARGCNCAYACNGARTAYTCNGARAARCARAARMGNGGNGCNGGNTAYGCNAGYYTN GCNYTNATGCARTCNTTYYTNGARCARMGNCAYGCNAARGCNYTNCARGARYTNGARYTN GARATGAARGCNGARYTNGARAARAGYAARGGNGARYTNAAYCARCARYTNGARGTNGAR YTNMGNAARGARYTNGARTCNGARMGNCARAAYYTNYTNACNCARYTNGCNGCNGTNAGY GAYATHTCNCARTCNGAYYTNCARAAYGCNGTNACNGCNAARCARTCNGGNCARAAYGAY TCNAARYTNGCNAARMGNYTNGCNAARGAYYTNAARGAYAAYGTNGARMGNGCNMGNTCN GCNATGTCNGTNCAYMGNGAYGAYCCNMGNGAYGAYGAYTAYGGNTAYMGNMGNAGYMGN ACNGAYATGGARAGYAAYAARCARTAY---CCNAARAARGGNMGNAARGGNTCNGCNGTN TCNACNCARMGNMGNGGNAGYGCNMGNAARGCNTTYGCNGAYGARCARGARGAYGARGAY ------------------------------------------------------------ ---------------------------------------------------------GGN ACNGARGGNGTNCAYTTYMGNTGYCAYGTNAAYMGNGGNCCNATGTAYGTNATHAARAAY ACNGTNGAYATHGTN---------------------CAYGTNAAYCCNATHACNAARGAR GARACNATHYTNAGYAGYGCNTCNGGNYTNGTNGCNAARCCNGARTTYTAYTCNGTN--- GARCCNGAYACNCCNGAYGTNGCNAAYTCNGTNATHTTYGAYTTYACNATHAARAARGTN MGNTAYCARGAYGAYGGNATHTTYAARTGYCAYGTNCAYTCNGGNGGNAARAGY---GAY TCN------------------GTNGARYTNGTNGTNCAYMGNCCNYTNTCNACNYTNAAR YTNAARYTNGGNGAYYTNGARCCNTTYGARCARACNYTNACNGAR------------CCN YTNAARYTNGAYCAYGGNGAYTAYAARGTNGCNTGYATHGCNGARGGNAGYAAYCCNGCN ACNGARGAYGTNCAYYTNTCNTTYGAYGGNATHATGACNCCNCAYAGYGCN---CCNGCN GTNACNGCNATGGARGGNCCNGAYMGNAARTTYCARACNGARATHACNACNGAYTTYAAY ATHGTNGTNAGYAARTCNGGNAARGARYTNGCNTGY------CARGCNACNGAYTCNACN GGNCARACNAARACNGTNAARYTNACNTTYGARGTNAAYAARTAYGAYCCNATHGTNACN TGYAAYGAYAGYGTNGCNCAYATHGGNCARTCNAAYCCNGTNGTNTAYTGYGTNGTNAAY TAYACNGGNYTNGARGTNGAYGGNTAYTCNTAYCARATHGGNGAYTCNGGNGARATHATH AARGARGGNGAY---------ACNAAYCCNGAYAARATHGCNGTNACNGTNTCNGAYGTN TCNCCNGGNGTNGCNATHGTNTCNYTNGAYYTNCAYMGNGCNGARGARAARTAYYTNGAY AARCAYTAYTAYYTNATHATHGAYATGGTNGGNGGNCAYACNGTNAARGAYAGYGTNACN YTNTAYAARAARGARGCNCCNGTNACNGAYAAYGGNGGNACNAAYGARGGN---TCNGGN TCNGGNATHGGNGARGCNACNYTNAGYTGYCCNTCNGGNAGYGTNATHAGYATHGAYGAR GCNYTNYTNGGNGCNAAYCARTGGTTYGARTGYGTNYTNACNGAYGARGAYTGYACNCAY TCNACNAARATHTTYMGNAAYTGYGARGGNYTNAAYTAYTGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MGNAARGAY GCNGTNGARGTNTTYAARYTNATHYTNCARTGYATGGGNGAYAARTCNTGYMGNAARTTY CAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNAGYGARACNGGNAGYTGYAGYGGNGGN GGNGCNGTNAAYYTNTCNGAYACNTAYGCNGCNGGNTTYYTNTAYYTNGCNAARYTNGGN ATHGCNGCNCARAAYTGYCAYCARGCNGTNATHMGNCARAGYTTYTAYGGNGGNTTYTAY GGNATGYTNGAYCCNGARYTNGAYCCNYTNCCNGAYTAYTGGTCNGCNYTNYTNTTYAAR AARYTNGTNGGNACNMGNGTNYTNMGNGCNTCNYTNMGNGGNAAY---AAYAARGTNCAY GTNTAYCCNTTYTGYTCNAARMGNAAYMGNAARGAY---------------GCNGTNYTN YTNGTNATHAAYTTYAAYMGNTAYCCNGTNAAYTTYTTYATGCCNGGNCAYYTNCARAAR AARGTNAARAARTTYGTNYTNACNGCNCCNMGNGGNAAYATHCAR---TCNAARGGNGTN YTNYTNAAYGGNATHMGNYTNMGNATGGAYAAYTTYAARTTYCCNMGNYTNAARGGNGCN ACNACNMGNCARCCNGTNMGNYTNYTNAARACNAGYTAYTCNTTYYTNGTNATHAARAAY ATGCAYYTNAARGCNTGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNATGGGNCCNMGNCCNYTNMGNCCN GGNGCNCCNATHMGNCCNGGNGGNCCNATGGAYGGNTCNGTNMGNCCNMGNGAY------ ------------------CCNATGGAYGGNYTNGTNMGNCCNMGNGGN------------ ---------------------CCNATGGAYGGNCCNGTNMGNCCNMGNGGNCCNATGGAY GGNCCNGTNMGNCCNGGNGGNCCNATGGAYGGN--------------------------- ---------------CCNATHMGNCCNGGNYTNATHGGNCCNCARACNGCNCARCCNGCN MGNATHTCNGAYCCNATGAAYGAYCCNMGNTGGTCNGCNATGMGNGGNYTNYTNGARTCN GGNGGNACNGARGARGTNGTNYTNGAYGAYAARCCNTTYGARYTNMGNATGGGNACNGCN MGNAARYTNMGNYTNTAYGAYCARGTNTTYGARGTNMGNGTNGAYYTNAARGARMGNGGN ATHTGYATHAAYGGNGARYTNYTNTAYAARYTNGGNGARCCNATHAARGARGTNAAYATH AAYGGNMGNCCNGTNMGNYTNTAYTAYCAYGGNYTNCCNAARCCNATHTGGYTNGAYGGN CARTAYCAYGARATGMGNYTNGAYGCNCCNCCNMGNAAYGTNYTNGTNGAYGGNTGYATG MGNGGNTTYCARATHGAYGGNMGNGAYAAYATGYTNYTNGTNGAYMGNATHGARAARGGN MGNTTYGGNGGNCCNCCNMGNAARATHCAYATHGCNGGNATHGARCAYGAYATHAGYTTY CARTTYCCNCCNMGNACNATHYTNATHGAYGGNAARCCNTGYGCNYTNAARYTNGAYAGY AARATHCCNTAYGTNGTNATHGARGGNAARCCNCAYGGNATHMGNTTYGARGGNGARCCN MGNGTNATHTTYATHAAYGAYCARGCNTTYAARATHCCNYTNGAYAARGCNGCNAARATH MGNATHGGNCARMGNCCNACNTAYATHGCNTTYGGNGGNCCNGCNCAYGARATHATHATH GAYGGNAARTGGTTYGARGTNAARTTYGAYAAYACNATHAARGAYATHCAYYTNGGNAAY MGNCAYTTYCARATHMGNATHCCNGGNCCNYTNCCNMGNGTNAARATHYTNGAYGARYTN CCNACNAAYTTYGAYGTNTCNAGYYTNATGATGAARAAYTCNATGGGNATHCARMGN--- CARYTNTCNACNAGYYTNMGNCCNGARGAYATHGGNCCNCARGTNCCNGGNCAYATHCAR ------------AAYCCNTCNATH------GCNGAYCARATHAARAARATHCARCARGCN ------------------------------------------------------------ ------------------------------------------------------CARATH YTNMGNTCNYTNTCNCARCARCCNMGNGCNACNYTNGCN---------------ATGCCN AAYCCNAAYMGNCCNCAYYTNCCNCARAGYYTNATHTCNGGNATH--------------- ------------------------------------------------TCNMGNATGACN CARCARTCNCARTCNAAYGCNGGNATHATGYTNTCNGGNATHGTNMGNCCNCARTTYCCN YTNCARGCNYTNGARYTNGGNGGNACNYTNCAR------CAYCARCCNAAYGTNGCNTCN CARGGNCCNGTNAAYGARATGTCNAAYGCNGCNATHATHAGYCARTCNYTNGAYGAYGCN ---------------GCNMGNTCNYTNGGNCARCCN------------------------ ------------------------------------------------------------ ---ATGAGYAGYCARTCNACNGCNYTNYTNTCNGGNGTNCARGGNTCNYTNGCNACNTCN AGYCCNATHCCNTCNGTNCCNGGNTCNGCNGCNYTNGCNGGNGCNGGNAAYGTNGCNACN CCNAGYACNGTNYTNGGNACNCARCCNCARTCNAGYTCNGTNGGNYTNCCNCCNTCNYTN ---ACNGCNGCNYTNGGNYTNCCNGGNYTNTCNGCNGCNCCNACNCARACNCCNGCNAAY CCNTCNGCNACNAGYTCNAAYCCNATGGAYATHAAYAGYYTNYTNAGYAAYYTNATHAAR GCNGGNYTNATHCARGAY---------------------------------------TCN AARACNGAYAARGCNACNCCNAAYGCNACNAARTCNCARCCNCCNACNTCNACNGTNGAY TCNAARCCNGCNAARCCNAARCCNCAYATHCCNAAYYTNTTYGAYTTYGAYGCNGAYYTN YTNAARATHCCNTAYCARMGNGTNGTNGAYGARYTNCAYGARGGNATHCARTGYCAYACN TGYTCNGCNMGNTTYACNGAYGARGAYCARGTNAARTAYAARGCNCAYYTNGAYTGGCAY TTYMGNCARAAYAARYTNGARCARGARATGGTNAARGTNGCNAARAAYMGNAARTGGTTY TAYACNATHACNGAYTGGATHCARTAYGARGARYTNGARGAYAGYGARGARAARTCNMGN AGYGARATHTTYGARCARATGMGNYTNGTNAGYGARCARTCNGGNTCNGGNAGYCCNCAR MGN------------YTNMGNGCNYTNGARGGNAARGARGTNACNACNAAYCCNGTNGCN ACNGGNGTNGARGGNGARGAYGTNTGYGCNACNTGYGGNGAYCCNTTYGAYCARGTNTGG AAYGARGARACNGARGARTGGATHYTNAARAAYACNATHAARGTNAAYGGNAARACNTAY CAYCCNATHTGYTTYGARGAYATHCARGARACNCCNACNCCNGTNGCNGAYCCNAGYAGY AAYCCNYTNGAYAGYGARATHCARAARATHCARTCNGAYGAYACNCARTGYGTN------ ---ATHAAYCCNGAYGTNAARAAYATHAARATHGARCCNAAYCCNAAYGCNGAYACN--- ------------GAYTCNGGNGTNAARAAY---ATHAARYTNGARATHCAYGCNYTNGAR GAYACNTGYGARATHAARAARGARCCNGTNGARGARCCN---GARAAYTCNGTNCCNGCN GARCCNTTYATHAARACNGARCCNATHTCNGARGGNGAYATHCCNGGNATHTCNTCNGAR YTNCARGGNATHAGYAAYTCN------GARGAYGTNCCNGTNAAYAARGCNMGNAARGTN ATHTCNGTNTGYCCNGARGAYCCNAAYTCNCCNTGGGARATGGAYTCNAAYCCNACNCCN GARYTNTCNMGNACNCCNAGYCCNYTNCCNYTNTAYACNMGNATHATGTAYCAYACNGGN GARAARCCNCAYATGTGYAGYGTNTGYGGNAAYGCNTTYTCNMGNAARGCNACNYTNAAY GAYCAYATHAARATGCAYACNGGNGARAARCCNCAYCARTGYTAYATHTGYGGNAARAAR TTYTCNCARAARTCNAAYTTYCARTAYCAYGTNAARACNCAYATHGGNAARGARTCNTGY ATHTGYGARGTNTGYGGNAARACNTTYTCNGAYAARTCNTAYYTNGARAAYCAYGTNMGN ACNCAYAAYGGN---AARCARTTYAARTGYAAYGTNTGYGARAARACNTTYTCNTAYAAY TCNCARYTNGTNAAYCAYACNMGNAGYCAYACNGGNGARAARCCNTAYGGNTGYGAYATH TGYGGNAARAARTAYGGNGARAARTAYGCNYTNAAYAARCAYATHAARTCNCAYGGNGTN GARAARACNTAYGAYTGYGGNGTNTGYGGNMGNATHTTYTAYMGNAARTCNCAYYTNGAY AAYCAYYTNMGNTCNCAYMGNGGNGARGCNTCNTTYGARTGYGARATHTGYGARMGNCCN TTYGCNAARAARGCNACNYTNAARAARCAYCARAARACNCAYGARGAYGAYGARGAYGAY GAYGTNGAYGARTTYACNGARGAYGARATHGCNNNNGAYCCNTCNAARMGNATHYTNTGG GCNTCNGARAAYAAYAARATHGAYATHGTNGARGARYTNYTNAARGARAGYCCNGAYTTY GCNYTNGCNTGYGAYAGYGAYGGNTAYACNCCNYTNCAYMGNTGYTCNTAYAAYAAYCAY CCNGAYATHGCNATHATHYTNYTNTCNCAYAAYGCNAGYATHAAYGCNMGNACNGTNGAY GGNTGGCARCCNYTNCAYAGYGCNGCNMGNTGGAAYTCNGTNGARACNGCNCARATGYTN ATHCAYAAYGGNGCNGAYGTNAAYGCNCARACNCAYGGNTCNYTNACNCCNYTNCAYATG GCNGCNTCNGARGGNCAY---GGNCARATGYTNGARYTNYTNYTNTAYAAYCCNTTYATH GAYATHACNGTNGTNTCNAARGGNGGNGARACNGCNMGNCARATHGCNCARMGNACNAGY TGYCAYCAYCARYTNTTYGARYTNYTNGAYGCNAGYATHAAYCAYYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TGGGAYAGYGTNCARGTNYTNTGYYTNACNAARATHGAYATH CAYGTNGCNACNCARTGYGTNGTNGAYAARTAYCCNTCNGTNGTNGCNAAYTTYTCNTCN YTNTGYTAYCARGGNGAYGTNAAYAARTAYTCNTCNATGGTNAARTCNATGGARAARGTN YTNAARTTYTCNACNACNAARCCNGCNAARGAYGARCARGTNTAYGTNAARGCNTAYAAR GARYTNYTNACNAARYTNGCNGARYTNTTYCCNCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNACNTAY GAYAARGAYAAYGAYYTNYTNCARGAYGAYAAYTGYGCNGTNMGNTTYGARGGNGGNTGG TGGTTYAAYTCNTGYCAYGAYGTNTTYYTNAAYGGNATHTAYGGNAGYACNGARTAYGCN AARGGNATHAAYTGGTTYTGYYTNACNCAYGCNTCNYTNAARMGNGTNGARATGAARATH AARATH------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARACNTTYTTY CCNTCNCAYYTNTCNMGNGGNACNACNACNYTNTCNGTNCCNAARTCNTCNGCNYTNYTN MGNCCNGGN--------------------------------------------------- ------------------------------------------------------------ ---------AARGARGTNYTNATGAARMGNYTNTCNAARMGNYTNATGTAYGTNYTNMGN TAYGGNGCNYTNAARGARGGNYTNGAYGTNGAYGCNAAYGGNTAYGTNGAYGTNGARGGN GTNYTNCARGTNCCNYTNYTNAGYGARTAYTCNCARGAYGARATHATGAAYGARGTNAAR ACNTCNATHTCNTAYMGNAAYATHCAYMGNTAYGARTGGAARGARAARGAYAARMGNACN YTNATHMGNTCNTCNTAYYTNMGNMGNTTYGARGCNAGYCCNTTYCAYCCNGGNACNCAR GTNAARACNYTNATHGARACNAGYATGATGTGYATHYTNGAYAAYYTNGAYATGTTYGAY YTNGARGAYTTYCARGAYGARCAYACNATHAARYTNATGATHMGNMGNYTNAARMGNAAR AARGCNGTNACNAAYAARGCNYTNTCNGTNYTNYTNGTNCCNACNATHACNMGNATHGAY YTNGARGGNATHTAYYTNACNAAYAAYACNATHMGNATGYTNTGGACNCARTGYCCNCAY YTNMGNGGNATHAGYYTNMGNAAYTGYGGNTAYATHATHACNGAYACNGTNYTNACNMGN YTNGTNAARAAYYTNCCNYTNYTNGARCARYTNAAYYTNTGYMGNTGYGCNCAYYTNACN GAYAAYTGYYTNGCNATHATGTCNAARMGNYTNACNCAYYTNAARGTNYTNCAYATHGCN GGNGTNCCNYTNATHAARCCNAARGCNGTNTCNAAYTTYYTNGAYACNGCNAARGARYTN ACNTTYYTNGAYGTNTTYTAYATGAAYACNACNCARGAYGARTTYGAYTCNYTNATGAAR AARGCNGARTGYGTNGGNGTNAARYTNGTNYTNCAYTCNCCNAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNCCNTAYYTNGGNAGY AARATHAGYYTNATHTCNAARGCNGARATHMGNTAYGARGGNACNYTNTAYACNATHGAY CCNAAYGARGCNACNGTNGCNYTNGCNAARGTNMGNTCNTTYGGNACNGARGAYMGNCCN ACNGAYMGNCCNYTNCCNGCNMGNAAYGARGTNTTYGARTTYATHATHTTYMGNGGNCAY GAYATHAARGAYYTNCAYGTNTGYGARCCNCCNAARCAYTGYCAYACNGARGGNGGNGTN CCNCCNGAYCCNGCNATHGTNAARTCNTCNCARCCNCCNCCNGGNCCNGCNGGNGCNGCN TTYCAY------CCNGGNGCNGGNGGNTTYCARCCNGGNCARTCNTAYCARCCNTTYACN CCNCARCCNYTNTTYTAYGGNCARGGNGGNCARTCNGCNCCNGGNTAYCCNCCNCCNCAY CAYGGNCARGGNGGNTCNCARGARGARGTNTCNTCNATHGTNGARCARTCNCCNGARCAR AAYATHCAYGGNTCNGTNGCNGCNATHGGNACNMGNCCNATHTCNGGNTCNCARACNTCN ACNCCNCCNYTNAGYMGNAARTCNCCNACNTCNGAYCARGGNGTNCARGTNCARCCNMGN AGYCCNGARAARTCNAGYAAYGARAGYGTNCARCAYAGYCAYAAYTAYCAYAGYCARCAR AAYCAYCAYCAYCAYCAYCARCARMGNGARTTYCCNMGNGGN------------GGNATG MGNGGNGGNCAYCARMGNATGGAYGGNCAYCARMGNGGN---------MGNCCNAAYGAR GCNMGNGGNGGNATHACNTCNTTYGTNMGNGGNMGNGGNAAYAAYMGNGGNCARCARATG MGNGARGGN---GGNAAYGTN---MGNGGNCARGGNCAYCCNMGNCAYMGNGGNMGNGGN GGNMGNTCNTCNGARCCNYTNAARTTYGAYACNGAYTTYGAYTTYGARACNTCNAAYGCN CARTTYGAYAARAAYACNATHGARAARGARYTNAARAAYYTNAGYYTNAGYGAYAARTCN GTNAAYGGNGAYAARACNGAYGAYGAYCCNGARATHGARGARGARGARGGNCARGARGAR GARGAYGARACNGTNTAYTAYGAYAARAARAARTCNTTYTTYGAYAAYATHAGYTGYGAR GCNACNGARAARAAYAARGGNCARMGNGTNACNTGGMGNGARGARMGNAARYTNAAYAGY GARACNTTYGGNATHTCNGARAAYTAYMGNMGNAAYTTYMGNGGNMGNGGNGGNTGGMGN GGNGGNAAYCCNMGNGGNGGNTGGMGNGGNMGNGGNMGNGGNGGNGGNTAYAAYMGNGAR GGNGGNTAYTAYGGNAAYMGNGGNGGNAGYMGNGGNMGNMGNCAYGAYTGGGAYTAYGGN GAYMGNMGNMGNATGGAYGCNCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CARCAYTTYACNAARAAYTGYCCNAARYTNAARMGNYTNTTY YTNACNTGGTCNACNCAYYTNACNACNTAYGCNTTYACNAAYACNYTNGCNTGYTCNAAY ATHACNCAYYTNGGNYTNGCNGAYMGNCARGARMGNGAYCCNTAYYTNAAYTTYGTNYTN CCNAAYTTYCCNCAYYTNGTNTCNYTNACNGTNAAYGGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYTAYCCNGCNGAYGTNGARGTNTCN TAYGAYGARTTYCAYTTYGTNGARMGNGTNYTNCCNAARGARACNATHCCNGAYATHCCN CAYCAYTCNTCNTAYCCNACNCCNTCNGGNTGGGTNCCNCCNAAYGAYGARATHMGNTCN AARCARCCNTAYYTNGTNMGNMGNACNAARAAYCAYGTNYTNCCNGTNTAYGCNGAYCAR ACNGARGTNTGGGGNMGNATHAARCAYCAYGTNACNATHMGNCAYATHGARGGNGAYATH TGGAARYTNGARTCNGAYYTNMGNGARCAYYTNYTNGGNGTNYTNCARACNTAYAARATH AAYACNCARGTNCAYGARGTNAGYMGNTGYATHMGNGTNMGNGGNGAYCAYMGNCCNATH ATHGCNCARTTYYTNATGGAYAARGGNATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AAYAAYTCNGTNTTYATHYTNCAYTTYCARGGNTCNCCN TTYYTNATHATGAGYAAYGCNMGNGTNAARGARACNACNYTNYTNACNGARTCNYTNGTN AARGTNTTYGGNGCNGARAGYYTNAARTAYATGCARYTNTCNGAYMGNCAYGTNTTYTCN YTNGCNGAYATHGTNYTNAARAARGAYTTYGARACNCARAARGTNCAYGGNTTYMGNGAR YTNGAYGARAARGARAAYCCNYTNTCNAARAGYGAYMGNAARMGNAARMGNACNGARGAY GTNTTYCAYGAYACNAARGTNATHCAYGAYGARAAYAARGTNGARAARMGNATGMGNYTN AARCAYGTNGAYAARGCNTTYGGNCCNGGNTCNCARCCNGCNYTNGARAARYTNGARTAY AARTTYGAYATHCARAGYAARCARCARGGNATHGCNATHATHMGN------ACNGARGTN CAYATHAARGGNAARTCNGTNYTNGCNGGNATGAARCARYTNGCNAAYAAYGGNTTYATH AARTTYCCNYTNCCNMGNCAYYTNACNAGYGTNYTNTCNGAYCARMGNAAYAGYTTYACN ATH--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AARAAR MGNMGNMGNACNTTYGARYTNGARGARCCNACNYTNAGYGGNGAYAGYACNCCNGTNATH GARACNGAYCARCCNMGNMGNYTNAARACNTCNMGNAAYAAYACNCCNCARAAYAAYTGY GGNGARGGNCARCCNATG---AARMGNYTNMGNMGNGAYACNTAYGARAARTCNCCNAAY YTNCARGGNAARGAR------------------------------------AGYAGYCCN AGYACNMGNGCNATHYTNGAYTCNATHAGYGGNGAYTGYTCNAGYGCNGARMGNMGNGAR AARYTNYTNTCNGCNATHGAYAARAARGTNCARTCNAARATGGTNTCNAGYCCNTCNGGN TTYACNAARAAYCARCCNAGYCARATHCCNMGNTTYATGGCNTTYYTNACNAAYAARAAR AARGARACNCARAAYTCNTCNACNCCNGGNAGYAARAGYTGGGAYAARATHCAYAARAAR GARTTYGARAARTTYGAYTCNATHGAYGTNTAYYTNGARAARAARCARCARMGNAARGAR AAYYTNTCNGTNAGYACNAARAARMGNYTNGCNAARCARTCNCCNGCNGTNAAY---CCN GCNTCNMGNGCNGCNAARYTNGCNTCNACNGAYCARGAYAGYTCNAARATHTTYAARCCN ACNGTNACNTCNGCNAARAAYATHAGYTTYGAYTTYAAYAARATGCCNAAYACNAARGTN YTNAAR---CCNTCNACNAARGAYTCNTCNAARAARGCNGTNACNGCNTCNAAYGCNACN CCNMGNTCNAARGCNYTNAAYACNTCNTCNGCNMGNYTNCCNTCNGCNAARAARGCNCAY ACNACNCCNTTYAARTTYACNGGNYTNAAYACNACNGTNACNYTNTCNTCNAGYACNACN TCNTCNAARAARCAR---GTNTTYGAYATHAARGCNAGYYTNGCNAARCCNYTNACNTGG AARCCNCAYACNGGNAARYTNCARCCNATGGAYGTNAAY------AGYAARACNACNGTN CCNATHTCNAARTCNTCNGCNGGNGCNACNTCNCAYMGNGCNMGNAARATGATHTCNGCN AAYAARATGMGNCCNGTNCARGCNAARAAYATHMGNMGNGCNGCNCARYTNGAYMGNMGN AGYAAYCARAARTAYGTNGAYATGATGAARMGNMGNGGNYTNYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGCARTTY GGNTGYGAYTAYGTNTAYYTNGGNAAYGARGARGARGAYGTNGARGARGTNAARGTNTCN GCNGTNGAYGAYGTNGCNYTNTCNYTNAGYGAYGTNAGYGAYGAYGAYGGNGARACNTGY YTNYTNGAYATHYTNGAYACNGCNGGNCARGARGARTAYTCNTCNYTNAARGAYCARTAY GTNMGNGAYGGNAAYGGNTTYGTNATHATHTAYAGYATHGTNGAYAARCARAGYTTYGAY GARGCNGARGCNATHTTYMGNTGGYTNAARMGNYTNMGNGAY---GARGAYTGYCAYGCN ATHYTNGCNGCNAAYAARCARGAYYTN------AARAGYGARGCNGTNGTNAGYGARCAR GAYGGNAARGAYYTNGCNGARAARYTNGGNATHCCNTTYTAYCARACNTCNGCNAARGAR GGNACNGGNATHACNCAYGCNATGAARGGNYTNGTNMGNCARATHCCNMGNATHGGNAGY GAYTAYAARATHGTNATGYTNGGNGCNGGNGCNGTNGGNAARTCNAGYATHACNATHMGN TTYGTNAAYGAYGTNTTYGTNGAYGAYTAYGAYCCNACNATHGARGAYTCNTAYMGNAAR ATGATHAAYGTNGAYGGNYTNTCNGCNGTNAAYAARGAYACNAARAARGCNGCNAARAAR GCNAARAARYTNAARAARAARTCNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARAARCARATGTCNGCNGCNGAYATHGAYAARATGCARCARGARATHCARTCNYTNMGN MGNTCNYTNYTNAGYGCNAARMGNGAYMGNTGGGTNAARYTNCCNGTNCARGAYACNYTN MGNMGNATHATGAARGGNGARTCNTAYTCNYTNGARATGTAYMGNTCNYTNGCNGAYAAR MGNCARYTNGTNGAYTCNGCNGTNAARACNCAYGAYGGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNGGNAARMGNTGGMGNACNTCNMGNGARAAYMGNYTNGCNCAYTCN GTNGGNAARTCNGAYGARGARGARGAYGAYGARGARGARGAYGGNCARATGCCNATGGGN GAYGARATGAGYAGYTCNAAYAGYGTNCARGARACNAGYTCNTCNGCNGCNTCNCCNCCN CCNACNCCNGAYYTNAAYYTNGARATGGARGGNACNTAY---CCNAAYACNGAYCCNTCN MGNTGGAGYGTNATGGARGTNTAYGARTTYGTNYTNTCNYTNCCNGGNTGYTCNGAYTAY GCNGAYGAYTTYMGNTCNCARGARATHGAYGGNCARGCNYTNYTNYTNYTNAAR------ ------------------------------------------------------------ ---------------------------ATHCAYACNTCNACNMGNTTYGCNGTNGAYCAY ACNAARGARAARGCNATHGTNAARCAYYTNAAYTAYGTNGAYCAYGARACNTCNYTNGGN CAYGGNCAYACNCCNYTNGTNGCNYTNCCNGAYTAYTCNTAYCARGAYGGNMGNCCNACN GARYTNACNAARTCNTAYAARAARMGNCARGARMGNAAYTAYAAYYTNACNAARCARGTN GTNACNYTNTCNAAYGARGTNMGNTTYGCNCARAAYCARYTNYTNGCNCARCARGARGTN GAYAARMGNMGNGARGGNGARMGNAARAARGCNCARYTNMGNCAYAARGGNAAYYTNGAY TCNGARGCNTTYYTNCCNGGNYTNCCNTAYTGGATGAARGTNGGNTAYAARAAYGTNCCN GGNATHACNMGNTGGTGGAAYGGN---ATGGGNGGNATHYTNGAYACNACNAAYCCNAAR GCNMGNGAYTGGTTYTCNAARMGNYTNGARGAYTTY---GCNCARYTNGARATHGAYGGN TTYAARTTYGAYGCNGGNGARATGTCNTAYYTNCCNYTNAAYTAYAGYTTYACNAARGAY CARCCNAAYCCNAAYTAYTAYTCNAARTAYTAYGTNGARATGGCNTCNAARTTYAARGGN YTNTCNGARGTNMGNGTNGGNTAYAARTCNCARAARTTYCCNYTNTTYGTNMGNYTNYTN GAYMGNTCNTCNACNTGG------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGTCNATHGARYTNGTNACNAARTGYYTNGARYTNGAY------YTNAAYGTNACNGGN AARGGNTCNAARGGNAARAARAAYAARAARYTNAARACNAAYGAYGCNATGGARATHATH CCNACNAAYMGNCAYGGNGTNTGGAARGARYTNMGNAARGTNMGNAARAARCARYTNAAR GARATHAARAARAARMGNAARGCNGARATHTTYAARTCNGCNATHGARGTNTAYAARGAY AARCAYGAYATHGAYCAYACNGARAGYAAYGTNGARACNYTNYTNAARATHTCNAARYTN GGNAARGTNGAYACNAARTGYGCNGARAARATHYTNTAYCAYCARCCNTGYMGNYTNTCN MGNGAYATHAARCCNGGNACNGARGTNTCNGARCCNACNACNGTNTTYACNGARGAYGAY TTYGARGCNTTYGCNAARGAYTAYCARCCNAAR------ATGTCNGCNCARCAYGTNGCN GGNGGN------------AAYCARCAR---------------------GAYMGNCARAAY MGNAARYTNYTNYTNGARCAYATHCARGARCARAARAARMGNTAYGGNCAY---CAYTCN TCNTCNACNCCNAGYCCN---ACNCCNTCNATGAGYTCNAGYCCNGCNCCNATGACNAAY AAY---CCNTCNTCNGTNCCNGGNYTNTCNGCNGCNGARTAYGCNACNATHAAYAAYCCN CARCARMGNGCNGCNYTNCARCAYGCNCAYGCNAAYTCNGTNGGNTTYTTYATHACNCAR GAYTCNTCNTTYGGNAAYYTNATHYTNCCNGTNYTNCCNMGNGARCCNGARCCNAARTCN GARACNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARAARGGNMGNGTNTCNYTNTCNTTYTTYGAY MGNYTNTCNACNCCNAARTTYCAYMGNAAYCARGAYGAR------CARAARGAYACNCCN GCNAARAARGARTCNCCNATHGTNMGN--------------------------------- ------------------AARACNTCNTTYMGNGARAAR--------------------- ------ACNAARGCNGAYTCNAGYTCNACNACNCCNMGNCAYACNCCNMGNMGNGAYCAY TCNGCNTCNTCNCCNMGNCCNTCNGGNGGNAARAGYATHTCNCCNGCNCCNAGYATGTCN AARTCNGCNTCNGCNGCNTCNCCNMGNATHACNCCNCCNCCNTCNTCNTCN--------- ------------ACNTCNTCNTCNCCNCAYCCNATGCCNAGYATHAGYGTNACNTCNCAY GGNAAYGCNCCNGARGAYGGNACNGCNACNCCNMGNGCNGGNGGNACNAAYCARGAYATH TCNAARGARGARTAYAARGCNAARATGGCNGARAARMGNMGNCARGCNMGNGARAARGCN GARMGNGARGCNGARGARGARMGNAARMGNYTNGARGARGARMGNYTNGCNGARGARGAR MGNATGMGNCARGARGARGARGARCARYTNMGNYTNGARGARGARACNATHMGNYTNGCN GARGARGCNMGNAARGCNGARGARGARMGNYTNCARMGNGCNATHGARGCNGARGARMGN MGNAARAARGARGARGCNGARMGNYTNGARCARGARMGNAARGCNAARGARGARGCNGAY MGNAARGCNAARGARGARGCNGARMGNATGGARMGNGARAARCARGARMGNGCNAARAAR GARGARGARGARMGNATGGARMGNAARAARAARYTNGARATGATHATGAARMGNGTNAAR ATHGAYCCNGCNCAR---------------------------GAYACNTCNYTNAARYTN GAYAGYCCNGTNAARTCNTCNGGNAGYTCNCCNAAYMGNAGYGCNYTNGCN--------- ---TCNCCNGARGTNCARGARATGCCNCCNTTYGGNCARGARCARGARAAYTCNTCNGGN TCNGARGAYGGNAARCARAAYACNGTNCCNACNCCNGCNTCNTCNGTNAGYGCNGARAGY TCNGARATGCCNTCN--------------------------------------------- ------------------------------------------------------GARCCN GCNGCNYTNACNCCNGTNGTNMGNAGYGCNTCNTCNGGNGAYATHATHGAYAGYGCN--- GCNGAYGARGAYAARAARGARATGGARAARGGNGAY---------AGYYTNGGNGCNYTN AAYACNCCNGTNAARTCNACNAAYGGNACNGCNTCNGARCCNTCNTCN---ACNGARGTN AARTCNMGNTTYAARTCNCCNYTNYTNCARCAYYTNGTNGARAAYAARGGNGGNTCNGAY TCNCCNAGYGGNACNCCNAARTTYAARTCNCCNYTNYTNCARAAYYTNYTNGGNAARACN AARGTNGGNGCNMGNATGGGNYTNTCNGCNAGYATGGGNGAYYTNAAYYTNAAYAARGAY AGYCCNAARGGNGGNAGYGCNCCNCARCARCARYTNCARGARTCNAGYYTNTCNTCNTCN TCNYTNAGYCCNGCNGGNTCNAGYAARGARATHTCNAARGCNGGNCARGAYGARGAYAAR GAYGTNGAYGARTCNATHGGNTCNTCNGCNTCNTCN------ACNTCNGGNAAYGAYCAR GARTCNTTYGARGAYCAYYTNACNAAYGGNAARTCNTCNGGNTCNGARGGNGAYGARGAR GAYGCNGTNGTNACNGAYAGYAARTTYTCNCCNATGGGNATGGTNGAYTCNGCNYTNGGN TCNAGYATHGARCCNCAR---CARGGNGAYGCNGCNGAYTTYTTYCCNACNCCNGTNATG TCNAAYGGNCAYGGN------------GCNAARAAYATGGARGAYTCNAGYATHAGYGTN GAYACNCCNGARACNYTNTCNGGNCCNCCNTCNGTNCCNACNTCNTCNTCNCARGAYGAR ACNGARGARGARGARGARGARGAYGAYGGNGAYGGNMGNTTYGARCAYGTNATHGAYYTN CCNTAYTCNACN---------GGNAAYAGYTCNTCNAARGCNTCNCCNATHATHGCNTTY GARGARAAYAGYYTNMGNACNGCNGAYGTNGGNGARTCNATGTCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATHAAYTCNAAYGGNCARGTNYTNGAYTCNCARTCNCCNTGGMGN YTNTCNTTYATHACNGAYGCNATHTGGGGNTTYATHAAYTTYYTNGTNYTNTTYTTYCAR ACNATGATHAAYCCNAAYAARAAYAGYMGNGGNGARAAYTAYACNTCNGAYTAYMGNMGN CCNGGNGGNGGNGGNCCNCCNACNMGNMGNATGGGNGGNTTYMGNGGNGGNMGNGGN--- ---------------------------ACNATHATGTGYTCNAARTGYMGNAGYCAYAAR TTYCCNGGNTGYGARATHTCNCCNCCNGCNCCNACNACNTGYGTNTCNTCNGGNAGYGGN ATHCCNGARTCNTGYTCNATHGTNMGNGTNTTYAARAARACNGGNGCNYTNGARCARTTY ATHMGNAGYTGYTCNAAYTCNAARGARACNAARTGYTTYGAYAGYMGNCCNGGNTAYGAR ACNTGYGCNCAYATH--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATHMGNGAYCCNTAYATHTCNGGNACNCCNCARGAYTAYGGNAAYCARCCNCAR GGNTAYATGATGGAYAAYCARTTYTCNCAYYTNCCNGCNCCNCCNCCNTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGTCNAGYGARGARGARGAYTAY ATGTCNGAYGCNTTYYTNYTNCARTGYGCNGAYACNMGNCCNGGNYTNGCNCCNAARCAY AARCARAARCARTAYGARAARGARAARAARGARAARGARTCNAAYMGNMGNAAYAARACN GTNCCNGTNAARCARYTNGARATHCARCARMGNGARATGGGNYTNAGYACNAGYATHTCN CARAAYAGYAARGGNTTYGCNATGYTNCARAARATGGGNTAYAARCCNGGNACNGGNATH GGNAARTCNGGNGARGGNMGNGTNGAYCCNGTNGGNTTYGARGTNAARAAYAAYMGNTCN GGNYTNGGNAARGAYYTNGAYATGAARMGNAARTCNTCNGARATGAAYAAYATHMGNGCN GCNATGYTNGCNAARMGNAARAARGTNCAYGARAARCARGCNCARTCNTTYCARAGYMGN ATGAGYGAYAARTTYAGYGAYAARYTNCARGARAARGAYYTNMGNGCNGCNCARAARGCN TGYATHCARYTNGAYCARAAYGCNGGNYTNGTNAAYCCNCCNGARCCNTTYTTYTGGCCN GARAAYAGYATHATHCCNGTNGARGARCCNGAYAARAARGAYGARGARGARGARTCNGAY GAYGAYTGY---------------GAYAAYGAYGAYGGNGAYAARGARGARGARGTNCCN TAYTAYYTNTAYTTYAGYGTNGCNGARMGNACNGARATHGTNACNMGNTAYYTNMGNAAY GTNTAYMGNTAYTGYATHTGGTGYGGNACNAGYTTYGARGAYGARGCNGARATGAARTCN ATGTGYCCNGGNAAYTCNGCNGAYYTNCAYGARTAYAAYACNGCNYTNGAYYTNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TGYCCNAGYTGYAARMGNGTNTAYGGNGAYAARGTNGGNAAYTGYCCNGCNGGNACN ATGATGTGGAAYMGNATHGAYAAYYTNATHYTNGGNCAYGARCAYTGYAAYGGNGCNATH GARATHACNTAYATHATHAGYGCNGGNACNCARGCNCAYGGNCAYCCNAAYCCNGGNACN CCNTTYAARGCNAARGGNTTYCCNMGNCCNAAYTAYYTNGAYAAY--------------- ---------------GTNACNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARYTN GARGCNCARGGNGTNACNGARGAYTGYYTNCAYGARACNYTNAAYMGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTNTTYCARGARGARAAYACN CCNTTYGTNCCNGAYATGATHGCNTCNCAYTTYYTNCAYTGYTTYATHGTNGTNTGYCCN YTNCAYAARCARGGNGARCCNCCNMGNTAYCARATHTCNATHGCNGCNMGNAARGAYGTN CCNMGNTTYTAYCCNCARYTNCCNCARCCNGCNGARTTYTCNAARGGNGARGARTTYMGN GARTTYYTNYTNACNAARYTNATHAAYGCNGARYTNGCNAGYTAYAARGCNGAYCARTTY GCNAARYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGAYCAYCAYTAYGGNGTNGCNGTN ACNAAYAARTTYGCNYTNTTYACNGAYGAYGAYGARGAYCCNATHGARATHAAYGCNCAR AARGAYGARGAYAARAARGCNAARGCNAARGARGARGAYGAYAARAARGCNGAYAAR--- ---------------------------CCNGCNACNGCNACNACNCAYAAYGARGAYGCN GARCARAAR---------GARGTNGGNGAYAARCARTGGCARACNGARAARGGNMGNGGN AGYGCNAARAAYMGNGARCCNMGNGARYTNMGNGARAAYGAYGGNGAYMGNMGNCCNMGN ---MGNCARGGNCCNMGNGARTTYAARGAYGGNAARCARCCNMGNGAYTTYAARGAYGGN AARCCNTCNMGNGAYTAYAARGAYGGNAARGCNGGNGAYGARAAYGTNCCNCCNGARMGN GARCARCCNCAR---ACN---GGNTTYAARMGNMGNGARGAYMGN------GARGGNAGY GGNTTYGGNGGNGARMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNGGNMGNGGN GGNGARMGNGGNGGNGGNTTY------GGNCCNMGN------------------GGNGAR CARAARMGNGARTTYGAYMGNCAYAGYGGNACNGAYMGNACNGGNATHAARGCNATHGAR AARAARGARGGNCAYGGNGCNCAYAAYTGGGGNAGYTTYMGNGAYGAYATHGARGARCAR GGNCARATHAAY------------TCNCCNGARGARACNACNGARMGNGARAAYCARCCN GARAARACNGARYTNAAYGARAGYGTNGARGGNGGNAAYGCNACNGARGARGAYGCNCAR CCNCARCARATGACNYTNGAYGARTGGAARGCNYTNCARACN------AAYAARCCNAAR CCNAARTTYAARATHMGNCARGCNGGNGARGGNGTNGAYTCNGGNCARTGGAARCARGGN GTNGARTAYCARAARAARCAR---------GAYGARAGYCARGCNCAYGGNGARCAYGAY GARGAYGAYCAYGGNGAYYTNGGNCARGGN---AAYAARCARYTNYTNTCNGAYATHMGN ATHACNTTYAAYGAYAAYCCNMGNMGNGGNMGNGGNMGN---MGNGGNGGNMGNGGNGGN ATGGARMGNGGNGGNGGN------MGNGGN------GGNMGNGGNGGNMGN------GGN ACNGCNMGNGGNTTYAGYAAYAAR---AARGARGCNGCNCCNMGNTTY---GAYGARGCN GAYTTYCCNTCNYTNYTNAARACNGCNGCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNGTNMGNTCNGARCCNGTN TCNTTYAARCCNGARGCNYTNACNAARACNTCNCAYTCNTCNTTYTAYTCNMGNCAYGGN GGNATGAAY---GGNMGNACNGGNAGYCCNAARAAYAAYCARGARAAYGGNAAYGCNGAY AARAARTCNTCNTCNCAYTGGTCNAGYTCNGGNCAYAARYTNGGNCCNACNTCNCARMGN YTNCAYCCNCCNACNTTYCARAAYCCNACNGARAAYGCNTTYAARAAYTCNMGNTCNMGN MGNCARAAYCCNTCNCCNTTYGAYTAYGAYATGAAYGAYTTYATGGARGCNAARCARTTY TAYATHATHGGNATHAGYGGNGTNACNAAYAGYGGNAARTCNACNATHGGNTCNMGNYTN TCNAARGCNYTNCCNAAYTGYACNTGGATHTGYCARGAYCAYTAYTAYYTNGCNGCNGAY GAYCCNMGNGTNGARATHGARCCNAAYGGNATGCARAAYTGGGAYAARYTNAGYGCNYTN GAYATGGAYACNATGYTNAGYGAYGTNTTYGCNTGGATHGARMGNCAYAARACNYTNACN CCNCCNTCNCARGCNTTYYTNGTNATHGARGGNTTYACNATHTTYAAYCAYMGNCCNATG TCNAAYYTNTGYGAYAARAARTAYTTYYTNCARGTNGAYMGNGAYACNGCNTAYGAYMGN MGNTGYACNMGNGTNTAYGAYCCNCCNGAYYTNCCNGGNTAYTAYTCNGARATHGTNTGG CCNATGTAYYTNAARAAYYTNCARGAYATHGARGAYCARAARGAYATHGARTAYGTNGAY GGNYTNTTYGAYYTNGAYACNYTNTAYCARCARYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNCAYGTNMGNCAYMGNAAYAARAARCARMGNGTNAARAAYGCNAARGTNGAR GGNGAYAARGARAARAAYTAYATHTCNAARAARAGYGTNAARAARTTYCARTCN---TCN ATHCAYGAYYTNCARGAYACNGGNACNATHATHGCNAAYAARCCNGTNGAYAAYGTNTGG GTNMGNMGNTTYTAYCCNTAYCCNAARTTYTCNATHGARACNGCNATGGARMGNCAYAAR AGYTTYGCNCARCCNGCNATGYTNGAYAAYATGGAYGGNYTNGTNTAYYTNGAYATGYTN YTNGAYTTYACNACNAARAARAARACNAARTTYATGAARAAYATHCARTCNACNATGYTN YTNCCNCAYCCNTTYAARTGGGGNMGNCCNCCNTCNATHYTNGTNTTYTGYAARGARGAR GARCAYACNAAYYTNGCNATGTCNYTNGGNGCNAARCAYGCNGGNCCNCCNGCNGAYGTN ATHAARATGATHGARAAYGGNGTNYTNAAYCCNAARGARTTYGAYCAYGTNYTNGCNACN GCNGAYTGYACNGTNGARATHACNCCNGCNMGNTCNTAYTTYMGNGAYAARTTYCCNCAR MGNGCNAARGGNAAYYTNGGNACNGAYYTNAAYGTNATGTGGACNYTNTTYTAYACNGGN TAYACNTAYGARTCNATHAGYYTNTCNGARTCNCARGGNAARYTNCARGTNCCNGTNGGN CARYTNAAYCARCCNACNAAYGARYTNGTNGCNAAYGTNGARGCNTTYATHGARTCNATH TGYAARCAYMGNAGYGTNGCNYTNGGNCCNTTYATHATGTCNATGGCNGTNGTNGCNCCN CCNTCNCCNGARGARTTYYTNATHAARGTNGARGAYTAYGTNCCNGGNTAYMGNAAYGAR GARGTNGAYTCNGAYGAYGARGARATGGAR------------------------------ ------------------------------------------------------------ ---GARGAYGARGAYGARYTNTCNTTYGAYAARGGNGARATHATHCAYGTNATHCCNTAY GARGAYCCNGARGARCARGAYGARGGNTGGYTNATGGGNGTNATGGAYTCNAAYGGNYTN ACNGGNGTNTTYCCNGARAAYTTYTCNAARAARYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYGCNTGGYTNYTNAGYGARTGGGGNCARTCNGTNTCNGCNTGY AARAARTCNYTNTCNTCNTCNATHGCNGCNTCNAARYTNCAYYTNATGTTYCCNTCNAAR GAYAAYATHMGNYTNAGYYTNGARGGNTAYAAYGGNGGNGGNTGYGTNCCNTAYTCNATH AARACNGCNTCNAARCARCCNTGGYTNACNCCNTTYTTYTGYCARTGGAARTCNGARGGN MGNGGNMGNTCNAARGCNGTNCCNCAYATHAARACNTAYACNMGNTCNTCNCCNGAYGGN TCNGARGCNGCNTGGTTYATGGTNACNAGYGCNAAYYTNTCNAARGCNGCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ACNAARAARTCNGTNGARATHTTYTAYGAYGTNGTNTCNCCNTAYTCNTGGTTYGCN TTYGARGTNATHYTNMGNTAYCARAAYMGNTGGAAYATHAAYYTNAARYTNMGNCCNTTY TTYYTNGGNGGNGTNATGCARGARACNGGNAAYMGNCCNCCNGCNATGGTNCCNAAYAAR GGNATGCAYYTNACNAARGAYGTNGARMGNTGYGCNMGNTAYTAYGARGTNCCNYTNGTN ATHCCNAARAAYCCNGCNGARYTNATGTTYGARAARGGNTCNYTNAARGCNCARMGNTTY YTNACNGCNGTNGAYATGAARTAYCCNGARAARGTNGARGCNGTNTCNMGNGARTTYTGG ATGMGNGGNTGGTCNMGNGAYGARGAYYTNTCNGARGAYTCNAGYYTNGCNGARGCNGCN AGYAARGCNGGNYTNAGYCARCARGAYATHCARGAYYTNYTNTCNMGNGTNAARGAYCAR GAYATHAARGAYMGNYTNAARAAYACNACNAAYGARGCNYTNGARYTNGGNGCNTTYGGN TCNCCNATGATHGTNGCNCARGTNAAYGGNAAYAARGARTGGATHTTYGGNAGYGAYMGN TTYCCNATHYTNGCNCARYTNYTNGGNAARATGAAYTGGGGNYTNTGGCARGTNTGYGTN TCNGGNGARATHAARGAYAGYTCNTGYAARATGTGGYTNGAYGARAAR------------ ---GAYGGNTAYYTNGAYCCNGGNATGTGGYTNAARGTNGCNMGNGGNATGGCNATHYTN GGNGCNGTNATHYTNGGNAARTGYGCNATHGGNACNGTNYTNGCNYTNATHGTNGARAGY MGNGGNGAYMGNCARAARTAYYTNCCNTAYATHATHTGYGCNTTYTGYTTYGCNGGNGGN TTYTTYTCNTTYGTNGGNGAYATGATHGTNGCNGGNAAYTAYAARTCNATHGTNGGNGGN GGNGCNGGNATGCARYTNTCNGARGGNGCNAARGAYYTNATHGGNGAYTGYTTYTCNYTN GGNTGGAGYTTYGGNYTNGAYATGGTNGTNCCNATHYTNGCNTGYATHAGYGGNGTNTGY CAYYTNYTNGGNMGNMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GCNAAYGCNAGYTTYTGYAARTCNCCN---CCNYTNCARATHCARTGYCCNATH TGYYTNGAYGAYYTNAARCARATHAARTCNAGYAARAARMGNGTNATGTCNACNACNTGY GGNCAYATHTTYTGYGARGARTGYATHGTNAAYGCNATHAARACNTAYMGNTCNTGYCCN ACNTGYMGNAARCAYYTNGGNCARAAYAARATHCAYCCNYTNTTYYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARTCNTGYAARYTNCARGTNAARCCNTTYAAYATHGCNMGNGARCARGAYCARMGN ACNYTNATHYTNCARTGYCCNYTNGGNATHGGNMGNGCNYTNGCNCCNGARTTYAARCCN GAYAARGAYTTYTGYTGGGCNMGNATHCARGGNGTNYTNGTNAGYAARAARACNAAYCAR ------YTNAARATHAARGGNAAYAGYAARYTNGTNCAYCARATGAARAGYAARGCNTAY GAYAARGTNATGAARATGTCNMGNGAYAAYACNYTNYTNGCNCCNAARMGNGGNACNAAR GARTTYYTNAARTTYGCNGCNTAYTCNGAYGAYGAYATHCCNTCNTAYTGGCAYCARAAR GGNAARGGNCAYGAYAGYCAYTCNTAYCARATGGTNGAYGTNGAYGCNAARACNTTYAAR GAYATHTCNGAYYTNYTNGTNAAYTGYTGGGAYCCNACNYTNACNGGNAARGGNTAYGAY GCNGCNAAYATHCCNCCNAAYTCNCARATHAARGTNACNAARATHCARMGNYTNGARAAY MGNCCNYTNTTYYTNMGNTAYTGYATGAARMGNAARTCNATGTTYMGNGAYATGYTNGAR MGNGAYMGNGCNTGYATHCARATHGARAARYTN------ACNGGNAGYAARGGNCAYGTN MGNACNAARGGNCARYTNCCNAAYTCNATGACNMGNGARYTNTAYCAYGARATHAAYGAR TTYTAYYTNTTYCAYGGNACNAARGGNGAYAGYYTNGCNTCNATHMGNAARCARGGNTTY GAYAAYMGNYTNACNAGYTCNGGNGCNYTNTTYGGNCARGGNGTNTAYYTNGCNGARAGY TCNACNAARTCNGAYCARTAYACNGAYCCNMGNGAYAGYMGNGTNGCNCARGGNACNAAY YTNAAYATGATHYTNACNMGNGCNTCNYTNGGNGAYGTNTTYYTNTGYAAYGAYAARCAY GARAGYGTNCARACNAARAAYTCNACNAARYTNAARMGNCCNCCNTGYYTNTCNTGYTCN AARGAYGTNTGYAARTGYGGNGARGCNYTNTAYCAYTCNGTNATGGGNGAYGGNAARTGG TTYGTNGTNTGYTAYCCNGARTAYTTYCAYMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GCNYTNACNTTYGAYAGYGTNGARGAYYTNGAYAAY TTYTGGYTNYTNCAYAARAARAAYMGNYTNACNCCNGCNTTYCARGAYATHYTNGTNGAY MGNTCNYTNYTNAARYTNGCNAAYTGYTCNAARYTNACNYTNMGNGTNAARYTNTGGGAR GAYGARGTNATHGGNTGYAARGARGAYYTNAARMGNMGNACNGAYTCNMGNGTNAARYTN ATHAGYTCNGAYMGNGAYTTYGARYTNGTNAARMGNATHCARGAYTAYCARAARTCNATG CCNGAYMGNGTNGTNMGNGCNMGNGAYGCNGARAGYCARTTYGARCAYAARYTNGGNGAR TTYATGYTNACNATHAARCARATHYTNCCNCARAAYACNCARGTNATHAARTCNATHAAR GARTTYCAYACNAAYYTNAARATGGCNMGNGGNGTNAARMGNGTNAAYTAYGAYAAYATH GAYCAYTAYYTNCAYTCNYTNGARTTYTTYMGNAARTCNTTYCARGARATHGARMGNCAR YTNGTNCAYCCNYTNTGYCARATHCARGGNATHTGYGARAAYGARAARCARCAYAAYYTN AARAARATHGTNAARAARGCNACNTCNGARATGYTNGGNTAYYTNAARCCNGAYGTNGAY YTNCARAARGTNMGNCAYAARGARTGGGARGGNAARGTNYTNACNMGNGARCAYGGNYTN TTYTAYGGNYTNATHAGYYTNATHCCNATGAGYGTNGAYMGNYTNACNACNATHGAYTAY ACNGTNGAYGARTAYATHAAYGAYTTYCCNGARATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNCCNYTNGTNAARAARGTNAAYATHCCNAARAARYTNGGNTGYAARYTNAGYACN GARAGYYTNTCNYTNATHAARTCNAARGARAARGTNGAYMGNAAYGGNMGNGTNTGGGAR GAYGGNGARGTNCARTCNTCNAAYAGYGAYGCNTCNAAYAARGARGAYAGYGAYTCNGAY AAYGAYGGN---TTYCCNTCNGAYACNGGNTCNATHAAYTCNGAYAARGAYGAYTGGAAR AGYTCNTCNTCNAARCAYAARAARAARCAYAARCAYAARCAYAARAARAARAARAARAAR AARYTNAGYAARGARAARGAYAARAGYGARGAYGARAARGAYGGNAARAARTCNAARGAR AARGARAARGARAARGARAARAAYAGYCARAARGAYGARGARGGNAGYTCNAAYTCNAAR AAYAAYGAYGAYCAYGAYGGNGAYAARGAYAARAARTCNGAYGAYMGNGTNAARGAYAAR GARATHGGNGARGARAARTCNAARAARGGNGAY---GGNGAYTCNGGNATHCARMGNAAR GAYMGN------------------------------------------AARAGYTCNGAY AARGAYAARAGYGAYAGYMGNAARMGNGARAARGARAARAARMGNAARCAYGAYMGNTCN MGNTCNMGNTCNCCNAARMGNTCNAARMGNTCNMGNTCNMGNTCNMGNTCNCCNMGNAAR TCNATHMGNAGYAAYAGYCCNMGNMGNAGYMGNTAYGGNGARTGGGAYGCNMGNMGNTAY ACNGAYGAYCCNAARAARTTYTCNMGNTCN---CCNGAYMGNAARMGNGAYAARTCNAAR GARMGN---GAYAAYGAYMGNGAYYTNMGNYTNCARATHGAYAARGCNAARYTNMGNAAR ATHGCNATHGCNAAYGCNYTNAAYTCNATGAARTCNGGNCARCCNGTNCCNGCNCARYTN GAYGTNGCNACNGTNAARTCNGGNGGNAARTCNGTNGARGARYTNACNGAYTTYTGYAAR MGNATHTCNGARAARGARCARGARAAYGCNGAYACNCCNATHAGYGAYAGYAGYGARGAR GARGCNGCNCAYAGYGAYGARGARGARCCNYTNATHCAYCAYCCNTTYAARGTNAARGAY ATGACNGCNAAYATHGTNATGAAYATHMGNAAYGCNAARCARYTNCCNGTNYTNACNCCN TCNGARAARCARGCNCARCARGCNTCNYTNMGNYTNGCNTTYCCNGTNTCNAGYGGNACN CAYCAYMGNGCNAGYGARTCNGARTGGGTNCCNGTNGAR------------------AAR ACNACNACNCCNGCNCCNYTNACNAGYAARCCNGTNAAYTCNATGAGYACNACNGARTCN CARCCNGARGTNAARGAYAGYATHTTYCCNTCNGCNGCNCARAAYGTNGAYATHGGNGCN ATHATHTCNGARMGNYTNCARGCNGTNMGNAARYTNCARGCNAAYCCNTAYGAYGTNCAR GCNYTNACNTCNATGCAYAARGCNCARGARAARGCNAGYCARTGGGCNCARTCNAARCAY YTNCCNGGNCARTTYGTNGGNAGYACNGGNGCNCARGTNATGTCNCARCARGARYTNATG GGNGAYAARMGNMGNCARGCNTGGGTNAARAARACNCARTTYAGYACNGCNACNCCNGTN AGYGGNGGNATHGGNATGTTYYTNYTNCARAARATGGGNTGGAARCAR------------ ------------------------------------------------------------ ---------------------GGNMGNAARGGNYTNCARAGYGCNGCNGAYCAYCCNAAR GCNGCNCAYGTNCCNCARGCNAARGAYYTNTCNCAYAARCAYCCNGTNTCNGCNYTNATG GARYTNTGYAAYAARMGNMGNTGGGGNCCNCCNAAYTTYACNGTNGTNCARGARGAYGGN CCNGCNCAYAARAARTGYTTYYTNTTYAARGTNGTNGTNATHACNGTNAARGARAARGGN ACNGCNGTNYTNCCNTGYTCNGTNATHCAYYTNAAYGAYTAYAARGTNACNTGGATGACN CAYTCNTCNYTNGTNCARACNATHGARGARMGNMGNATHGTNAAYGAYGAYMGNATHAGY GTNGAYMGNCCNTTYCCNAAYGAYTGGAAYYTNMGNATHAGYGAYGTNMGNMGNAGYGAY AAYGGNGARTAYGTNTGYTCNATHAAYACNAAYCCNGTNMGNATHAARTAYGTNTTYYTN AAYGTN------ACNYTNTCNAARACNGTNTCNACN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNAARCARTTYCCNAARGTNGCNGAYACNCCNGAYYTNATGAARATH TTYMGNACNTCNTGGTTYGARAARYTNAARGAYATHMGNAARGCNGARAARMGNGAYGAR GARTAYATGAARGARATGTTYMGNCARGTNTTYATGGARTCNGTNTAYCCNGTNCAYCAY GTNGCNACNYTNCCNGCNTAYMGNATGGGNGAYGARGAYAAYGAYAARATGMGNCARGAR ACNATHGTNMGNCAYAAYGARATHAARMGNGCNAAYAARAGYGCNYTNGCNATHYTNYTN TCNCCNAAYATGGTNTTYCAYCCNATGATHYTNGAYGARGTNGCNTAYAAYGTNATHGGN TCNAAYTGYYTNAAYAARACNCAYTCNGCNYTNGTNGTNCARGCNGARGARYTNGGNTGY GARGGNAARGTNGARGARGCNCARGGNGTNATGAARYTNGTNGAYCARYTNAARGARGAR MGNCAYCARYTNGARGTNMGNCCN---GCNATGCARGAYGAYGGNGGNCCNYTNATGAAR CARATGGARGTNTGYGAYGTNTGYGGNGCNTTYYTNATHGTNGGNGAYGCNCCNCARMGN CARGAYGARCAYYTNATGGGNAARCARCAYGCNGGNTAYGCNCARGTNMGNGCNGARATH GAYMGNMGNAARAARMGNGTNMGNGAYGARACNGARGCNMGNGARGCNAAYGARACNMGN YTNMGNYTNGARMGNGARGARMGNGARAARGARMGNCARMGNGARMGNGAYGARMGNMGN CARMGNGARAARGAYACNGARMGNMGNMGNGAYMGNGAYATGMGNMGNMGNAGYMGNTCN MGNAGYMGNGARMGN------GGNAARGAYMGNMGNMGNTCNCAYAGYMGNGARMGNMGN MGNCARMGNAGYTCNAGYMGNGAYMGNMGNAGYMGNMGNAGYMGNAGYMGNAAYMGNGAR ------------------AGYTCNAGYMGNAGYAARMGNTCNMGNMGNTCNTCNAGYMGN GAYMGNAARMGNGAYMGNMGNMGNTCNMGNGAYMGNAARTCN------------MGNAGY MGNTCNMGNGAYMGNAARAAYMGNAGYMGN---GAYAARGAYYTNGARMGNAAYGGNGGN AGYATHAGYAGYMGNGARGARAAYAGYMGNGAYAARGGNGAYAGYAGYACNTCNATHACN GAYGAYAGYYTNGTNACNTCNTGYTCNAARGAYTTYATHGARYTNYTNTCNTCNCAYTTY AAYGGNAARTTYGGNAARAAYTGGGARGAYYTNYTNGCNYTNTAYGGNTGGAAYTAYCAR GARATHYTNYTNTTYCARAAYAARGAYCAYCCNMGNGGNTAYTTYTGYAGYATHYTN--- ------------------------------------------------------------ ------------------------------------------------ATGGAYTTYGAY TCNTCNTCNAARTTYATHGCNTCNYTNGCNMGNTTYYTNCARTCNYTNTGYAAYGGNTAY GTNGARTTYGAYAARGGNGTNGARGTNATHGGNCAYATHTAYYTNAGYGTNGAYAGYGAY ACNGGNMGNAARATHGAYTAYGTNYTNAAYGARAARGTNTGYAARAAYGAYAAYTCNGTN ACNTTYATHAGYAAYAGYTTYCAYGCNCARCCNGCNGARAARCCNCARCCNGTNYTNAAR AARCCNGARGGNGAYAARGGNAAYGARGAYTCNGTN------GAYGARTCNGGNCARTCN ATHCCNAGYAGYACNAAYGTNGGNACNATHAGYGCNCAYMGNGAYGGNTCN--------- ------------------AAYAARMGNCCNMGNTCNCCNACNCARMGNMGNATGGGNATG GGNMGNGGNTCNGGNGGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CCNACNAAYGCNAGYGCNCCNYTNGCNTTYGARGARATHGAYGTNGAY TAYGGNTAYGTNYTNTAYMGNACNATHATHCCNAARAAYTTYGGNTCNAAYTGGGTNYTN AARYTNACNAARTAYCAYGAYMGNGCNACNGTNYTNGTNGAYCARAARTTYCARGGNATH YTNAAYMGNAAYCAYAAYAGYAGYATHACNATHGARTCN------GGNATGGTNYTNGAY ATHYTNGTNGARAAYCARGGNMGNGTNAAYTAYGGNATHGGNATGAARAGYACNTCNAAR GGNYTNYTNGGNACNGTNAGYYTNAAYGGNGTNCARYTNGARAAYTGGCARATGTTYCCN YTNAGYATGAGYAARGTNTAYGAYGAYCCNTGYGGNTCNGTNGARGARACNTCNTCN--- ------------------------GGNGGNYTNGGNGCNCCNACNTTYGTNYTNTTYCAY TTYAAYGTN---------TCNYTNGTNGARGAYACNTTYYTNAARYTNGAYGCNTGGAGY AARGGNTTYGCNGTNYTNAAYGGNTTYAAYYTNGGNMGNTAYTGGACNACNYTNGGNCCN CARAARACNYTNTAYACNCCNAAR---------AAYGCNATHMGNTCNGARAAYACNYTN YTNATHTTYGARACNGAYGCNGTNCCN---CCNYTNYTNAGYGGNGCNTAYGTNGARTTY GTNGAYACNCCNATHYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------AARGGNYTNAARYTNCCNAGYCAR TCNGTNGAYYTNGARAARTCNAAYYTNTCNAARACNAARAGYGAYACNGAYYTNAARMGN AARGARGGNGARAARMGNCCNCAYGAYAARTCNACNAARGAYCCNTTYGARCCNGAYATH AARMGNTCNAARTTYGAR------------CARYTNAARCARCARAARGARAARGARGTN AARGARAARGARMGNGARAARYTNAARAARGARAARGARMGNAAR------GAYAARGAR GAYGCNCARAARYTNAARGAYAARGCNGARAARGARMGNAARGARAARGARYTNGCNGCN GTNAARCARGAYGTNGAR------GTNCCNAGYGAYGARGARGARGCNGCNCARCARATG GAYGCNGGNGAYTTYGCNATHGAYYTNGGNATHGCNTGYGTNGTNTGYMGNCARTTYGAY GTNAGYTCNGGNAAYCARYTNGTNGARTGYCARGARTGYCAYAGYYTNTAYCAYCARGAR TGYCAYAARCCNACNGTNACN------GAYGTNAGYTAYCCNMGNTTYGTNTGGTAYTGY TCNMGNTGYACNAARAGYTTYAARAARATGATHTCNCARAARCCNGTNAARTCNAGY--- AARCCNACNGCNCCNYTNACNTCNACNTCNAARGARYTNACNTCNAAYATHACNAARTCN AGYAARACNGAYTCNGAYTCNGCNAGYCARGCNTTYMGNMGNATGGAYCCNAARGCNATG GTNGCNCCNAARGAYACNAGYAAYYTNACNTCNTCNTCNAARGCNATGGTNGGNYTNGCN GGNYTNGCNGCNAAYYTNACNAARCCNMGNGGNGAYCCNAARAGYTCNTCNAGYTCNAAR AARTCNGARCAYAARGGNGAYGGNGCNAARTCNTCNTCNAGYAARTCNGARACNGGNTCN AARCARGAYAGYTCNGCNAARCARTCNCCNYTNCCN------TCNTCNATGAARAGYGAR TCNMGNAARTCNGARTCNAGYAARYTNTCNTCNTCNTCNGGNAARGARGARTCNMGNGAY GGNAARAARTCNGARTCNAARAGYAGYAGYAGYAARTCNGAYAGYAGYTCNTCNMGNAAR GARGARAARAARGARAARTCNGAYTCNTCNAGYGGNAARAGYAARGARGAYAARAARTCN GAYAARTCNTCNCCNAARCAY------------------------------------TCN GCNTCNTCNTCNAAYTCNCCNCCNACNACNCCNGTNTCNCCNGAYTCNCCN--------- ---AGYAARACNATHGGNGGNAGYAGYAGYAGY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GCNAARYTNYTN GCNYTNATHTCNAAYGCNCARACNTGGACNGCNAAYCAYAAYGARACNGGNAARTGYAGY GTNYTNYTNACNGCNCCNTCNMGNATHAARTCNYTNCARAAYGTNYTNGAYCARTTYCAY TAYGARYTNGCNATHTAYGARGGNCCNTCNAARGAYGAYGCNGGNTCNAARYTNTCNTTY ACNTCNAAYAARACNCARATHTCNGTNTCNTTY--------------------------- ------------------------------GTNAAYAARGAYYTNATHCARATHAARACN AAYGAYGARAARGARGTNCARMGNMGNATHGAYTCNTTYATHMGNAAYAARMGNAAYGAR GTNGAYGARMGNAAYATHMGNGARTTYATHTCNCCNTTYTGYTCNGAYCCNGGNAAYAGY TGYGCNMGNGTNGARGCNATHTAYATHCAYMGNGARGGNATGAARAGYCAYATHAAYYTN AARCAYGTNGARAAYTCNTAYGGNCCNCARACNMGNGGNMGNCCNGARGAYATHGAYGGN MGNAARTCNTGGATGATGCCNGCNGAYGTNCARMGNGCNGARGCNGTNGAYGARMGNYTN TCNAAYATGGARCARCAYYTNAAYATHACNGAYGAYGCNGGNGAYATHTAYAARMGNYTN AARGCNYTNGARGARMGNATHAGYTTYYTNGARGGNGTNTCNCCNGARTAYTTYACNCAY GGNATHCCN------------------------------------------------ATH GTNCCNACNAARCARATHACNGCNGARGTNGGNGGNCAYCCNACNGAYGTNATHGTNAAY AARTTYGARGAYCAYYTNTTYATHATHGCNACNCARTAYCARAARYTNGGNACNGTNGTN GARGTNTCNMGNGAYGTNATHAGYGAYGARGTNCARGGNCCNATHCCNATGTTYTCNACN AAYGTNYTNYTNGGNAARGAYGARCCNYTNACNCAYGTNATHGCNAARAAYATHGTNACN GCNYTNAAYCCNCCNATHCCNGTNATHYTNAGYYTNGCNYTNAARGARACNTCNCAYGAY GCNGTNCARGCNATHAAYGARYTNATHAARTCNTGYYTNATGGCNGCNCAYTAYCAYGAR GARGCNMGNMGNMGNCARAARGTNYTNGAYAARGCNTGYMGNGCNMGNAAYGARYTNGCN TTYGGNCARAARTCNGAYAARGTNGCNCCNGTNGARACNGGNCCNAAR------CCNGAR ACNATHATGTGYACNGAYCARGGNCARTTYTAYCARACNMGNCCNAGYATHCAYGTNTGG ACNGGNCCNGARMGNAAYMGNMGNACNTAYGAYMGNAGYMGNGARGGNCCNGTNYTNGGN AGYTCNTGGMGNCARYTNGARMGNGARATGAAYTAYMGNCARMGNAGYYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNAGYGAYATHGAYYTNTCNGCNGCNYTNAARGAY ATHYTNGGNTTYGAYYTNTCNTAYTAYCARATHYTNGGNCCNGGNGAYTGGGTNGGNTGG AGYACNAARACNMGNCARYTNAARGGNAARCARYTNACNYTN---------ATGCCNAAR TTYTAYGARGAYYTNGARGARAARCCNACNMGNMGNAARYTNGCNTGYGARGGNYTNMGN GAYGAYYTNYTNGARTGYYTNYTNAAYAGYGAYTGYTGYAARYTNGARAARAARACNCCN MGNGARTGYATG---------TCNMGNGTNGGNGAYCCNTCNGTNCCNGAYMGNTGYCAY CARYTNMGNACNTCNTTYTTYAAYTGYMGNMGNTCNATGYTNGAYATGMGNACNMGNTTY MGNGGNMGNAARGARAARGTNAARGTNYTNAAYGGNTGYGAYTCNYTNGAYGAYYTNYTN AARMGNAGYACNTTYACNTTYYTNTTYGTNACNAARTCNTTYGCNCARGARGARTGGTCN GARYTNATHTCNAAYGCNTGYYTNATGMGNGCNATHAARTCNAARMGNACNGTNGTNCCN GTNAAYTCNGARMGNGAYTCNCARATHAAYTTYAGYATHTCNACNYTNYTNGGNGGNATH AARCCNATHAAYTAYTTYAAYATHGAYCARTTYTAYYTNAARTCNYTNMGNGARATGTTY TCNACNGGNGCNGCNGARMGNTTYMGNMGNGAYGTNATHYTNGAYGAYCARMGNMGNYTN TAYTAYTGYGGNMGN---AARAARTCNGGNAARGGNGGN------YTNTCNAARGGNGAR MGNGCNGGNATHGGNATHYTNGTNATHGTNTGYGTNGCNGGNGTNGTNTTYGGNATHTTY GTNGTNTAYMGNMGNACNAAYATGACNAGYMGNGGNTTYAARGCNTTYYTNACNGGNGGN GTNMGNTAYAARACNTAYACNAAYGCN--------------------------------- GARGAYAARTCNMGNAARAAYGCNATHCARGCNAARATHAAYMGNGARAARAARAARGCN TAYATHAARAGYYTNGARGAYGARMGNGCNTCNYTNAARAGYGAYAAYGCNAARYTNAAR TCNGARAAYCARACNATGAARMGNAAYATHGCNGAYYTNGCNGARGARGTNGAYTAYYTN AARTCNGTNYTNGCNAAYTCNAGYGCNYTNTCNAAYYTNYTNMGNAAYATHCCNAAYGTN CCNGAYGTNAAYYTNTCNGCNACNGTNGTNGGNMGNAARMGN------TCNGTNGTNGAY GAYCAYAGYTAYAAY---TTYGARTCNTCNTCNTCNAARMGNYTNMGNTGYATHAAYGAR AAYYTNAARAARGCNGGNGTNTGYYTNCAYGTNAAYGGNGARTCNGCNAGYYTNGARTTY TGYGCNCAYTGYTCNAARYTNGCNYTNAARTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AGYACN YTNCCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GGNAARTAYTTYGTNGCNGTNAAYTCNGGNGCNGGNAAYCAYTCN AARGCNAAYGARAAYCAYAAYAARTCNYTNTGYAARACNGCNTGYATGCARGCNGTNGAR YTNYTNMGNTCNAARGTNTCNGCNATHGAYGCNGTNACNGCNGCNGTNMGNGCNYTNGAR AAYGAYGARAGYACNAAYGCNGGNTAYGGNTCNAAYYTNAAYGTNCARGGNGAYGCNGAR TGYGARGCNTGYTGYATGGAYGGNGCNTCNYTNTAYTTYGGNAGYGTNGGNGCNYTNTCN GGNGTNAARAAYCCNGTNGAYGTNGCNAAYYTNYTNGTNMGNGARCARATHCARGGNCCN YTNCCNTAYGGNMGNGTNMGNCCNAGYATHYTNGTNGGNAARGGNGCNAARACNTAYTGY ATGGAYCAYGGNATHGAYACNAAYTAYAAYATGATHTCNAARTCNGCNTTYAARACNTAY AAYMGNTAYAARMGNAARTGY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TAYGARAGYGAYTTYGAY TGGAGYAAYGARACNGCNAARGARGARMGNYTN------AARATGAGYYTNGCNAGYTAY CAYTCNCARTCNTTYACNCARGGNGAYAARTGYGAYYTNACNGGNTTYCCNMGNAARGTN GARATHMGNTTYATGTGYGARGARAAYTCNGARGAYTAYYTNTCNMGNATHGARGARTCN GARACNTGYGTNTAYACNATGAGYGTNATGACNTCNMGNATHTGYMGNCAYCCNTAYYTN MGNCCNCCNGTNMGNMGNAARGCNGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARACNGCNTCNGGNGTNGCNYTNGGNGCNGGNATHYTN GGNTGYGGNATGGCNATHTCNGGNGCNTGYCCNGGNACNTCNYTNGTNCARYTNGGNGCN GGNGTNGARAAYGCNTGGYTNACNATHYTNGGNGGNYTNTTYGGNAGYYTNGCNTAYGCN ATGGCNCARACNGAYYTNTTYCARAGYTAYAARACNMGNTTYCARCCNAARACNTAYTTY YTNGAYAARTAYYTNGAYGTNCCNTTYTAYAGYATHGCNGTNCCNYTNTCNTGYGTNYTN GCNGGNACNGTNTTYGTNYTNGARYTNYTNTTYCCNTGGGAYACNCARGTNGAYGCNTCN YTNGTNACNGARGGNGTNATGAARGCNGGNGCNTGGCCNCCNTTYATHGCNGGNATGATH GTNGGNGCNYTNCARATHCCNACNGTNYTNTCNAAYCARGAYACNYTNGGNACNGCNAGY TCNTAYGTNACNATHGTNTCN---------MGNATHTGGCCNTAYATHAAYTTYAAYAAY GARGARACNTAYYTNAARTCNTAYMGNAGYGGNATGAARAAYTGGTGGCAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYAARTAYTCNAARACNGCNCARCARYTNCARAAYGARGAYATH AAYYTNCCNAAYAAYYTNGARGARATGCARYTNYTNYTNYTNAARTAYMGNGARGARATH ATHTCNGCNAARGTNGCNAARGARCAYACNGARGARACNYTNAARAGYCARATGGCNTTY YTNAARTCNCARGTNYTNGGNGARCARCARGARAARGCNACNYTNGARGARACNYTNTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGTTYMGNTCNGARAARGAYYTNCCNTCNGGNATGYTNCCNTCN CARCCNTCNTCNCARATHTCNGGNTTYAAYGGNAGYACNAAYTTYTAYGGNCARGGNAAY YTNTCNYTNCARCAYMGNGCNATHGGNGCNAAYCAYTTYMGNGGNGGNAAYAAYACNGGN CAYATHACNCCNACNAGYATHAAYACNGGNTTYCCNYTNGGNYTNCAYCARCCNCARCAR CARCARCCNCARCARCARCARCAYTCNCCNAAYAGYYTNGCNGCNATHGGNTCNMGNAAY GTNYTNAAYGTNCARAGYCARAGYGGNCARCCNAGYYTNGTNAAYATGCARAARMGNCCN TTYAGYTCNTCNGGNCCNATGCARAAYTTYGCN---ACNTAYGGNTTYGGNGGNTCN--- TCNATGGARTCNCAYCCNACNATHGAYYTNTCNGAYTTYCCNACNYTNAGYAGYMGNTCN TCNGCNACNCCNAAYCCNYTNCCNTCNACNMGNAAYTAYGTNGGNATGGTNAGYAARCCN GCNCARGAYTCNGCNCCNGARTTYAAYATHTCNCARGARGARTTYCCNGCNYTNCCNGGN TCNCARAAYCCNCCNGTNCARTCNGGN---TCNGARTAYMGNGGNMGNGGN---MGNAGY AGYAGYTGGMGNGGNGGNCCNCCNMGNGGNGGNGGNTTYMGNGGNGGNMGNGGNGGNTAY ATGATHGAYMGNGARGGNGGNMGNGGNGGNTTY---MGNGGNMGNGGNGGNTTYTCNMGN GGNMGNGGNGGNCCNCCNMGNAGYMGNGAYGAYATGTCNCCNCCNMGN------ATGTCN MGNAGYTAYGAY---ACNGAYMGNGGNMGNGGNCCNCCNCCNAGYMGNMGNCCNGAYMGN TAYGARGAYAGYTTYGAYAGYMGNGGNCCNTCNATGMGNATGAARGAYATGTAYTCNTCN CCNCCNMGNGAYTCNGGNMGNAGYTTYGAYMGNCAYTCNCCNCCN---CCNACNMGNMGN GAYMGNGAYTAYAGYACN---MGNCAYAGYGAYCAYATGAGYTCNMGN---GAYTAYYTN CCNCCNMGNAGYTAYTCNCCNCCNMGNGAYACNGGNTAY---AGYATGTAYAARGAYTCN TAYAGYTCNGGNYTNMGNGARGAYMGNMGNCCNATGMGNGAYTAYCCNTCNTCNMGNGGN ACNAGYGAYTAYGAYCAYCAYMGNGGNGGNAGYMGNGAYTTYMGNGAYGGNGCNMGNGGN GAYTAY------AGYTCNMGNGAYTAYCCNCCNCCNTCNTCNMGNAAYGGNGAYTTYMGN GAYTCNYTNGGNAGYMGNGAYTTYMGNGAYGCNCCN---------MGNGGNGGNGAYMGN TAYGGNAGYGGNGGNMGNGGNGGNAGYAGYMGN--------------------------- ---------------GGNMGNTCNMGNTTY------------GARGAYAGYMGNGGNCCN CCNCCNMGNGARTAYAGYTCNMGNGGN---------------MGNGGNGAYMGNGAYGAY GAYMGNGGNAGYMGN------GGNTTYATGAAYGGNGGNTCNMGNGGNTCNMGNGGNGCN CCNMGNGGNMGNGGNMGNGAYTTYCCNGGNAGYMGNGGNGAYMGNMGNTCNCCNAGYMGN GARGGNGCNGGNGGNAARMGNCCNMGNYTNGAYTCNGGNGAYTAYMGNMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNAAYTAYMGNTTYTAYYTNGGNCCN GCNAARACNCAYATGYTNGGNGARGGNTTYAARACNATGMGNGCNGGNGCNGTNCCNTCN GCNTTYGGNYTNYTNAGYATHGGNGTNTCNTAYMGNACNAARYTNYTNYTNTCNCCNGAY ACNACNGCNTCNTCNGCNAGYGTNATGCARGTNACNGAYGAYTAYTTY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNAARAARAARAARGAYYTNGCNMGNAARGAYTCNCARCARGAYTCNGAY AGYACNGARGARATHTTYGCNAAYATHACNCCNACNATHTCNAGYTCNTCNMGNCCNMGN MGNTCNACNGAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNATHCCNYTN GCNACNTCNATHGARATGGTNAARAARACNATHTCNACNTTYGCNGGNAARYTNGTNAAY YTNYTNGAR------GARGTNYTNCARGAYGCNGCNATGTCNMGNAAYTGYYTNAARTGY YTNAARAGYTTYTGGTCNYTNTGYTCNMGNCARCARAAYGTNATHTCNTAYCARTGYTTY GGNAARTGGCAYCCNGCNYTNYTNGARGARATHACNCCN---YTNGCNTCNATHTTYATH GAYYTNTCNATHTCNGCNCAYGGN------CAYGAYGARAAYAARYTNMGNTGGTCNAAR AARYTNTAYAGYTGGYTNAAYTTYGAYYTNACNGAYMGNGCNATHMGNATHGCNYTNYTN GARGTNGTNGGNCAYAARAARGTNGGNGCNGARATHGCNGGNCCNATHYTNAGYCARGTN YTNMGNMGNAAYTCNAGYGARYTNTCNGAYCCNGAYTAYYTNYTNCAYTTYYTNYTNYTN AAYAARTGGCARGGNYTNACNGCN---GTNTCNGARATHGCNGARGARTCNAARYTNATH AARGCNCCNCCNACNTTYYTNTCNTGGGTNAGYTGYTTYATHCCNGAR------------ ---------------GAYATGAARGGNGCNTCNGTNAGYMGNTTYYTNYTNGAYYTNAAY ACNGAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GARCAYCCNGAYATHATHGTNCCNACNTTY MGNCCNCCNCCNGAYATHAAYAAR------------------------------YTNYTN GAYGCNCCNTCNCCNYTNCCNAARCCNCCNCCNTTYAAYAGYYTNAGYTCNACNTTYCCN TCNGGNCCNATHTTYCCNGAYTCNACNCARCARATHCARYTNAGYGTNCCNACNGTNACN TCNCAYGAYGGNAARTTYCARYTNACNATGCCNATHGAYGAYTTYAARCCNGARGARYTN ACNGTNAARACNCARGAYAARAARGTNATHATHTGYGCNAARMGNGARGTNYTNAGYGGN AGYMGNAAYCAYACNATGGARATGAAYMGNGARCAYAGYYTNCCNGAYAAYGTNGAYCCN YTNACNGTNAARGCNTTYTTYACNGAYACNAAYATGYTNATHGTNGARGCNCCNYTNATG MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARTTYACNGAYGAYGARATH MGNCARGARYTNGCNCARYTNGGNTAYCAYAAYGTNCCNCARGAYAARYTNGARGARTTY MGNAARGAYYTNATGGCNYTNATHGCNAARGARMGNAGYAARTCNAAYTCNATGAAYAGY AGY---------------TAYAAYTCNGAYMGNGGNGCNGTNCAYCARGGNTAYMGNCAR AARCARCARACNAAYGCNGGNCAYTTYGCNGAYGARAGYCARGARTGGMGN---GGNCAR MGNTTYAAYGARAAYTGGGARTAYCAYGGNGARMGNGAYGCNGGNCARMGN--------- ---------------------------------------------------CCNCARACN GCNCCNGGNGGNMGNMGNCAYTGYGAYYTNGGNGGNAAYAAYCARTAYTGYTTYCCN--- ------------------------GAYAAYGCNTCN---------------------GAR TCNAGYTCNGARGCNMGNTTYATGAARMGNAARACNTCNMGNAARACNCCNAGYGGNTGY MGNYTNGTNGAYGARTCNTTYACNGAYACNGARTCNGGNGTNTTYGARATHTAYGARAAR ATHAARAAYYTNGCNATGMGNGARTGYGARTGYGGNAARACNAARCCNAARTCNGGNGAY GTNGARCCNCCNTAYMGNATGAARGGNAARGTNAAYAARTAYCCNTCNTTYATHMGNAAR YTNGARCCNCCNCAYACNMGNAAYYTNGTNAARACNGAYGTNAAYGARMGNYTNAARATG TAYAARGARGCNTGGAARGTNCARCCNCCNATHGGNGARGAYCAYMGNATHCCNYTNMGN AARGCNATGCAYTCNAARYTNATGAARCARGARCARATHAARATGAARTCNAARGTNTAY ATHCCNAAYMGNTAYGTNCCNCCNCAYCARAARYTNMGNAARGAYGTNMGNTGGAAYGTN MGNCARGCNTTYGARAARTAYGARYTNCCNGCNCAYGGNTTYTAYCAYGAR--------- AARGARAAYGARGAYYTNMGNAARAARACNTCNCARYTNCAYATGGCNAAYAARGARTGG AARAAYMGNTGGGAYACNYTNAARAARCARAARGARGAYGARAAYGTNAAYYTNCARGCN CARGTNMGNCARYTNACNYTNGARATGGARMGNATGMGNMGNGAYATGGARCAYMGNATH GCNTCNCARAARGARGARYTNAARAARATGACNCARGTNAARAARGAYAGYGAYAAYGCN TAYYTNATHYTNYTNTCNGGNMGNTCNCARGARAARCARYTNYTNGARAARYTNAARCAR GAYTAYGGNACNYTNCAYCARGARAARMGNTCNYTNGARATHCARYTNGARATHYTNGAR GCNCAYAARACNGCNGARGARCCNGGNCCNACNAGYATHACNGCNGARYTNGARACNGAR YTNGCNGTNGTNAARMGNCARGTNACNYTNTAYATGGAYGAYTTYAAYMGNGARCAYAAR GARMGNYTNAAYGTNGARACNAARYTNCARAARGARMGNGAR------------ACNACN CARCARYTNGAYGCNAARYTNMGNAARACNCAYGCNYTNYTNAARGCNMGNGAYGARGAY YTNMGNGTNAARTCNAARAARGCNGCNGAYYTNCARTAYCARGTNGAYGAYYTNAARYTN AARYTNGARGTNGARCARMGNMGNTCNTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNGTNGCNATGYTNAAY TCNTGYTGYAARAAYGAYTCNGTNATGGCNGCNACNGTNMGNGCNCAYATGGTNTCNATH YTNTCNGARYTNGGNGARGAYGAYAARGAYTCNGCNYTNGGNGGNYTNATGGCNTGGATG CARGARAARTAYGTNGCNAARGCNGARYTNGAYGARAARYTNTCNYTNGTNGCNGCNAGY GTNACNGARAGYYTNCARTCNYTNYTNGCNGAYAARATHGCNGCNGARGCNCARGCNGAY ---------------------GARAARGCNGTNAARTCNATHGTNGARGARGCNYTNGTN CARTTYAGYGCNGAYMGNGTNGGNATGCCNGAYTTYGCNYTNGARTCNGCNGGNGGNAGY GTNYTNAAYGTNMGNTGYTCNGARACNTAYTAYMGNAARACNGCNYTNGTNAGYGTNTTY GGNGTNCCNYTNTAYTAYGCNTCNAAYTCNCCNMGNACNGTNATHCARCCNAAYGTNCAY CCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARTAYCARTGYCCNTCNMGNYTNGCNCARAARTTYTCNGARATGGTNATHYTNGAY CARCARACNAAYAARTCNGAYTAYCAYYTNCCNYTNGCNACNAAYGTNAAYACNACNYTN ATHGAYCCNMGNCAYCARAAY------AAYGARATHAARGAYCCNTCNTCNCAR------ ------CAYACNCCNGCNAARGARGCNAARATHATHATGMGNATHMGNCAYAARAARATG AARAARCAYAARYTNAARAARYTNMGNAARMGNATGTAYTTYYTNTGGMGNAARCARAAR YTNACNMGNMGNGCNAARMGNGAYTCNATHTAYTGGAARGGNATHGCNGAYATHAARAAR GARGGNGAYGAYTTYGAYGCNGARTCNTTYGTNAARAAYCARYTNAAYAAYGCNMGNMGN GGNGGNTAYTAYATHAAYGTNTTYGAYTCNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TCNTTYYTNTCNTCN------------CARATHGTNCAR YTNGTNCAYAGYATHATHGGNTTYATHATHGGNTCNTGYGTNTAYCAYATHYTNGTNGTN YTNYTNGGNGCNGCNTTYACNGARAAYGTNGARGARACNTTYYTNTTYTCNTGYYTNYTN TCNTCNYTNACNGTNTTYCCNYTNTGYATHGTNTTYGGNMGNTGGGARGARTTYGTNAAY AAYYTNCCNGAYCCNATHGAYCCNCARACNTCNYTNACNGAYGCNYTNAARATGGTNGCN ACNTTYTCNGTNGCNGGNGGNTGGGTNGGNGCNTTYCCNATHCCNYTNGAYTGGGAYMGN GAYTGGCARGCNTGGCCNATHACNTGYTGYGTNGGNGCNATHGCNGGNAAYATHGTNGGN TGGYTNGCNGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CAYGTNCARMGNTGYTTYTTYYTNTTYCCNACNATHGARMGNATG GCNGTNTCNCCNAAYGGNYTNTTYATGACNCCNYTNYTNMGNTAYTTYMGNTGGATGGTN GTNYTNYTNTCNTTYTTYTGYATHYTNATHCCNYTNCCNYTNMGNCAYATGATHGTNGGN TTYYTNTAYMGNAARGTNACNTAYCCNTCNTGYATHCCNCCNTCNATHYTNAAYACNGCN ACNCCNTGGACNTCNAAYTTYTCNACNTAYYTNGCNAARACNGARATGAAYAARGTNACN ATGYTNCARAARGAYYTNGTNMGNAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TCNATGGCNMGNGGNATGAARAGYAARAARYTNCAYGARGTNTCNMGNYTNTCNAGYYTN GTNAARGAYATHGTNAGYCARACNCAYTGYAAYYTNGTNGTNGAYGTNGGNTCNGGNYTN GGNTAYYTNGAYCAYGTNATHCAYCARACNTTYGGNACNCAYYTNYTNGGNATGGARACN GCNYTNACNCAYGCNTCNGCNGCNGAYAARMGNGCNGGNGARCARGGNATHACNTGYGAR GGNATHAARAGYYTNCARTGYCAYYTNGARGAYACNACNGARTCNTAYGARACNTTYYTN GGNCAYGTNGARTCNGTNTTYCCNACNYTNAARTGYGAYTGYCARTCNATHYTNGARGGN CAYACNACNGCNCARGGNMGNCCNMGNATHTGYYTNATHGGNYTNCAYTGYTGYGGNGAY YTNTCNCCNACNATHATGGCNYTNGTNTCNAARTGYCCNYTNATHAARGCNATGTGYTGY GTNTCNTGYTGYTAYCAYAARATGGCNTAYTCNAAYGARGARTTYGARAARTTYCCNYTN AGYGAYYTNGGNAARMGNATHTAYTCNCARCAYGCNCARAARAARGGNCAYCCNTTYATH ACNYTNTCNACNYTNMGNYTNGGNGCNCARGARACNMGNAGYMGNTGGMGNCARCARACN AARGARGAYCAYGARTGYCAYGTNAAYCAYGTNGGNTTYMGNGGNYTNGTNACNYTNACN GAYGARGAYGARYTNTCNACNMGNCAYAARATHMGNMGNTGYCAYTTYGARTCNATHCAR MGNTTYGTNGAYTCNTTYTAYGAYYTNCCNTCNCAYGAYAAYGCNATHACNGCNAARGGN GAYTAYYTNATGGAYYTNCAYGAYAARTAYAARMGNGAYTTYGAYGGNATHGARATHYTN ACNYTNYTNCARGTNTGYGTNCARCCNGTNATHGARTAYYTNYTNTAYGARGAYMGNGCN CARTGGYTNATGGARCARGGNCAYTCNAAYGTNCAYATHATHCCNGTNTTYGAYGAYGTN GTNTCNCCNMGNAAYYTNGCNYTNGTNYTNYTNAAR------------------------ ------------------------------------------------------AGYAAY AARGTNAARYTNACNGCNAARAGYGTNTGYMGNCAYYTNGAYATHYTNTCNGARYTNTTY TCNAARCARTGYAAYYTNGTNYTNGCNCARMGNATHMGNMGNACNTAYCARGTNYTNYTN YTNTAYMGNAAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNTAYGGNGARCAYYTN YTNAARGARTGGGARAARGARMGNACNGAYGARGARATHAARAARTGYTAYAAYGARGTN ACNGARGTNAAYCARYTNYTNAARCAYCCNGARAAYCCNGAYTGGGARAAYATHGTNGAY AARGTNGAYTTYAARGTNTGGMGNTAYAARATHCCNAAYTCNAAYYTNTTYAARTAYMGN GTNYTNGGNCAYTTYAARGAYATHCCNGCNMGNGCNTTYTAYAGYACNCARGTNGAYGTN AAYTAYTGGAARGAYTGGGAYAAYCARACNATHGAYGTNCAYATHATHGAYMGNGAYGGN AARACNGGNTCNGARGTNATHCAYTGGYTNTAYMGNTTYCCNTAYCCNATGAAYCCNMGN GARTAYGTNTAYGTNMGNMGNTGYACNGTNTAYCCNGARAARAAYGCNATGATHATHACN GCNMGNGCNACNGAYCAYCCNACNTGYCCNTAYGARCCNAARCAYGTNMGNGTNGARACN TTYATHTCNCARATGGTNATHACNCCNTAYACNTTYTTYGAYGARAAYGGNTTYTCNTAY GTNYTNTCNTAYTGYGAYGAYCCNCARACNAAYTTYCCNCCNGTNTGGTAYAAYTGGATG GCNAGYGCNGGNGTNCAYGARTTYYTNGARMGNYTNCAYAARGCNGCNYTNMGNAARCAY GARMGNGGNAAY---GTNGARATGACNACNAAYATHYTNAGYAGYGGNCCNTCNYTNTAY CCNGGNATGGTNCAYATGYTNYTNMGNYTNAARGARGTNGTNCARTGGACNMGNATGACN GCNYTNGARYTNATGYTNCAYYTNATHTCNGTNYTNATHTTYTCNYTNYTNGTNGCNACN AARGTNGARGGNGAYYTNACNGCNTCNTGGCCNATHYTNTTYACNCCNYTNTTYATHTGY GAYGGNYTNAAYGCNTAYYTNTGYGTNATHATHTTYGTNMGNCARTAYMGNGARTAYGAR YTNAARCARGCNTGYYTNMGNYTNTCNAAYTCNYTNTCNGTNATHGTNYTNATHTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GTN GARCCNCCNCCNTTYGARAAYGARGARGAYGARGTNAARGARGARGAYGAYYTNTTYTCN GAYGCNAARGARAARACNTCNTCNCCNGAYACNGTNACNCCNCAR------TCNGTNAAY GGNACNGAYGAYAAYCCNTTYGGNGAYGAYAARGAYGAYGARGAYGAYCARTTYAARGGN GGNAGYTCNGARATHAARYTNGARTCNGAYGARGARGARGARGTNTCNGAYGTNAAYAAY AGYCAYYTNTCNGCNCARGCNGARAARCCNGCNGARAAYGCNACNTCN------------ ------------------AAYGARGARGTNACNCCNGARATHGCNGTNTCNGARGTNGTN ACNGCNAARACNAARATHGCNGCNCCNTCNYTNAARGCNGAYGAYGGNGTNGARGAYAAY GARGAYGARAARGARCARTAYGAYYTNGAYATHAARATHACNGARAAYYTNAARATHGGN GAYGGNATGTCNGCNTAYATGGTNTTYAARATHGTNTCNAARACNACNAAYCCNGCNTTY MGNCAYCCNGARAAYGCNGTNYTNMGNMGNTTYAGYGAYTTYYTNGGNYTNTAYTCNAAR YTNGCNGARAARCAYGTNCCNYTNGGNATHATHGTNCCNCCNGCNCCNGARAARAGYGTN ATHGGNATGACNAARGTNAARATGTCNAARGARGAYACNGGNTCNATHGAYTTYATHGAR MGNMGNAARGCNGCNYTNGARMGNTAYYTNATHMGNACNGCNGCNCAYCCNYTNYTNGCN GCNGAYTCNGAYTTYATHGARTTYYTNGARAARGAYGGNGAYYTNCCNAARGCNACNAGY ACNTCNGCNYTNAGYGGNGCNGGNGTNATGMGNYTNTTYCAYAARGTNGGNGARTCNYTN GARAARATHACNYTNAARGTNGAYGARAGYGAYGARTGGTTYGARGARAARCAYCARCAR ATHGARGCNYTNGAYYTNCARYTNAARAARYTNCAYACNAGYYTNGARACNYTNGCNGCN CAYMGNMGNGARYTNTCNGGNAGYACNGCNGTNTTYGCNAARAGYGCNGCNATGYTNGGN AAYGTNGARGARCAYACNGCNYTNTCNMGNGCNYTNTCNCARYTNGCNGARACNGARGAR AARATHGARYTNGTNCAYAARGARCARGCNGARGTNGAYTTYTAYACNATGTCNGARYTN ATGAARGAYTAYGTNGCNYTNATGGGNGCNGTNAARGGNGTNTTYCAYGARMGNATHAAR ACNTAYAARCARTGGAARGAYGCNGARACNATGYTNGGNAARAARMGNGARAAYAARGCN AARYTNGARATGCARGGNAARACNGAYAARYTNTCNCARGCNMGNACNGARATHACNGAR TGGGARCAYAARGTNGARAARGGNCARGARGAYTTYGARAARATHTCNAARACNATHMGN AARGARGTNGCNMGNTTYGARAARYTNMGNGTNTCNGAYTTYAARACNAAYGTNATHAAR TAYYTNGARGTNYTNATGGARAAYCARGARAARYTNATHAARTAYTGGGARACNTTYYTN CCNGARGCNAARGCNATHGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARTGYCCNTTYGARGGNTGYGAYAARAGYTTYCCNTTYCCNACNGTNYTNMGNMGNCAY ATGAARGTNCAYCARGGNTAYCCNTGYGARGTNGAYGGNTGYGGNGGNGTNTTYGARACN TAYYTNAARYTNMGNAARCAYAARGCNGTNGAYCAYGGNCCNGAYYTNGTNTGYMGNCAR TGYCARACNCARTTYAARTCNMGNCARACNYTNGTNCARCAYYTNAARACNCAYYTNTTY GTNAARGARGTNTTYGCNTGYACNAARCCNGGNTGYGARMGNACNTTYYTNTAYAARAAR AAYYTNACNCARCAYATHMGNTCNTTYCAYYTNGGNGARAARGTNTTYGTNMGNAARAAR GTNTCNAAR--------------------------------------------------- ---------------------------------CCNAARGCNTCNATGGAYAAYGARGAR ACNCCNGCNAAYAGYAGYCCNGAYAAYGARGAYGGNAAYMGNCARGTNYTNGCNCCNTCN GARGGNCCNMGNGARGARYTNATHAGYACNGCNGTNAARTTYYTNCARAAYCCNAARGTN ATGGGNAGYCCNYTNAAYCARAARAARGCNTTYYTNACNAARAARGGNYTNACNCARGAR GARATHAAYYTNGCNGTNGARMGNTCNGGNGTNACNGAR------ACNGCNGCNGCNGAY GTNATHCARGCNMGNCCNCCNCCNCCNGGNTAYCARCCNGGNATGATG------------ ---GTNCCNTAYAAYCARATGCARCCNCCNATHCCNGCNCARTCNMGNTGGGCNCARGTN MGNGAYYTNACNYTNGCNTCNGTNGTNGTNGCNAGYGTNTCNTAYGCNATGTAYCAYYTN TAYAARACNTAYATHGARCCNYTNATHMGNGGNAARACNGTNCARGARAARMGNYTNGAY MGNYTNGARYTNCARGTNGGNGARATHCAYAARTCNGTNAAYGARTCNYTNTCNGARATH AGYMGNACNYTNGCNGCNATHCARATHACNATHAAYAAYCARAGYCARCARCCNCCNGCN AGYCARGCNGTNGGNMGNGGNATHACNGAYYTNAARGCNGAYATHTCNTCNYTNMGNAGY YTNYTNYTNAGYAAR------------ATGGCNGARCAR---ACNACNATHACNGCNAAR ATHGCNAARTGGTGGMGNCARGGNGGNTCNCARGGNYTNGAYCARAAYATGCCNAARTGY GAYCCNAARTCNATGATHCAYCAYATHGCNMGNYTNCCNGARTGYMGNAAYTTYYTNCAR MGNGARMGNAARMGNYTNYTNATGATGYTNGARATHTCNAAYGAR---AARGCNGAYGTN TTYGCNGCNYTNGCNAGYYTNGARGAYTAYATGACNAAYTTYCAYACNGCNYTNGGNTAY ATHAAYCARGCNYTNCARATHGARACNGARTGYGCNGARAAYYTNTGGYTNMGNGARAAR YTNTCNMGNCARTGYMGNGTNYTNGARGARCARAAYAAYGARAARATHAAYAAYTGYGGN AARCARYTNAARTGYCCNTCNATGAAYGARGTNCCNMGNGTNTCNGGNAARACNYTNAGY GTNGARGAYTTYMGNATGMGNTTYYTNAARACNAGYAARCCNGTNATHATHACNGAYATH GTNTCNAGYATGACNAAYGGNCCNTTYGAYTAYTCNYTNATHACNGARCAYGCNGGNGAR ACNACNATHACNACNAARGARGCNYTNTCNGCNTCNYTNGCNTGGGCNAARYTNGARAAY AARMGNAAYACNACNGTNGCNGARTTYATHCARGGNGTNCARAGYGGNTCNGTNAARGAY GTNYTNTTYGAYTGGAGYYTNCCNATHCAYTGYCCNAGYYTNGCNGARCARATHYTNYTN CCNGARTAYTTYAARAAYAAYTTYYTNYTNCARACNACNCCNGGNTCNYTNTAYMGNGAR AGYTGGCCNAGYYTNTTYATHGCNCCNAARGGNGCNACNACNCARYTNCAYGTNGAYGCN TTYYTNTCNCAYTTYTGGATGGCNYTNTTYAARGGNCARAARMGNTGGACNTTYTTYGAY GCNAARGAYACNGCNTTYYTNTAYCCNCARTGGTGYCARTCNYTNGAYCCNGTNTTYGAY ATHGAYCCNACNAARCCNGAYYTNCARAARTTYCCNYTNTTYGCNCARACNCAYCCNCAR CARTGYGTNYTNCARGARGGNGARYTNYTNTTYGTNCCNGCNGGNAGYCCNCAYTTYGTN GARAAYYTNACNGCNTCNYTNGCNATHTCNTCNAAYTAYGTNGAYTCNTCNAAYTTYGAY AARGTNTGYAARGARYTNAARATHAAYGCNTTYCARGAYCARMGNGCNGCNGAYYTNYTN TCNCARYTNCARGAYAARCAYTTYYTNCARAARGTNAARGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARTCNAARATHYTNTTYTCNMGN------ AGYAARGARAGYAGYGAYYTNMGNACNGCNMGNAAYYTNCARGARGARTCNTAYGARTTY ATGMGNGGNGTNATGGAYGARTGYACNCAYYTNGGNAAYTTYTCNGTNCCNGTNGAYCCN GARYTNGTNATHATHGTNTCNGCNGTNCARGAYGCNTAYATHCCNMGNGAYGGNGTNYTN CCNYTNGAYAARYTNTGGCCNGGNTGYGARGTNMGNTAYGTNGAYCARGGNCAYGTNGGN GCNGTNYTNYTNCAYCARGAYGTNTTYMGNAARGCNGTNACNGAYGCNTTYGAYAARCAR YTNCARAARTAY---------------------------------------AGYGAYTCN GGNATHAGYAARMGNGTNTTYTCNAARGARAGYMGNGAYMGNYTNATHGGNMGNGTNGAR AAYTCNATHTCNCCNGAYYTNMGNATGATGYTNYTNTCNGAYAGYAAYAAYATHTCNATH CCNGCNAGYATGAAYMGNACNGTNAAYCARAARYTNGTNGCNTCNGTNATGACNCARAAY CCNMGNGAYAGYGTNTTYTGYAARTAYAGYYTNMGNAAYTGYACNCARAAYAGYYTNGAR GGNTAYGAYTAYTGYATHMGNCAYATHYTNGARGAYMGNGCNGCNCCNTAYMGNCARTGY GCNTAYGTNATGAARACNGGNMGNAARTGYCCNTCNGCNGCNCCNAARYTNGARAARAAR GAYGGNTTYTGYACNTTYCAYACNAARAARGGNYTNYTNGCNMGNCARMGNYTNTCNMGN AARMGNMGNYTNAARGARACNCCNGAYAGYATGYTNGARGARYTNGTNGCNACNATGTCN GCNATGTCNAAYAAYCAYAAYGCNGARCCNMGNMGNGGNAARYTNAAYAAYGAYAGYATH GCNTCNMGNGCNYTNGAYTAYGCNAGYTCNAGYGAYTCNGARGCNGARCCNCCNYTNGTN GARCARGCNTGGMGNGAYTCNGGNGAYAGYGAYGCNGARAGYATHGAYAGYGAYCARGAR GAYGTNYTNAARTAYGCNGGNGTNTAYACNACNGARGARGTNGCNCARATHYTNMGNGAY AARYTNATHMGNYTNCARGCNYTNTAYATHGAYCARTTYAARMGNYTNAARCAYATHYTN TTYACNAARAARMGNAARTAYYTNAGYGCNCARAARAARGARAARGARYTNTTYGGNAGY ATHAARMGNTAYAARGAYGAYCCNCAYCARAGYGARAARTAYAARAARYTNTGYGCNATG AARMGNTAYCAYAARAARTTYGGNYTNGAYGCNYTNATGCARCAYCARTCNACNCARMGN MGNYTNAARATHACNGARGGNATGAGYCAYAARATGCCNATGCCNGTNCARTGYAAYTTY GTNGAYGARGGNYTNMGNTGYACNCARTCNGTNGTNCCNYTNAGYCARTAYTGYCARAAR CAYATHYTNCAYGAYCARCAYCARGTNYTNTAYMGNCCNTGYCCNTTYGCNGAYAGYCAR TGYGGNMGNCCNGTNCCNTCNYTNYTNGGNAAYCCNTTYTGYTCNYTNCAYCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATHTCNCARTCNAAY GARYTNYTNAAYAARCARAARTCNGAYATHACNGAYATHCAYTCNAARYTNAARGARAAR CARAAYYTNGAYGARGAYTTYAGYMGNGCNCARGARATGATHAARTCNYTNGAYAARGAY GTNTCNGARYTNAARATHAGYAAYMGNGAYYTNCARAARGAYATGGARTCNTGYMGNGAR MGNGARTCNAARATGYTNGCNYTNCARTCNGARYTNAGYMGNACNAAYGCNTGYYTNMGN TCNGARAAYACNACNYTNAGYAAYAARTCNACNAAYCARACNGCNGARATHGARMGNYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARTCNAAR AAYGAYGGNGAYGARACNTAYCARACNTTYATHYTNTAYGAYGARGAYCAYACNYTNGGN AAYGCNYTNAARTAYATHYTNAAYAARAAYCCNGARGTNACNTTYGTNGGNTAYAGYATH ACNCAYCCNTCNGARAGYAARATHAAYYTNMGNATHCARACNACNGGNAARCCNGCNATG CARATHYTNAARCARGGNYTNAARGAYYTNAARCARYTNTGYGGNCAYATHYTNACNACN TTYGARTCNTCNACNAARTAYTAYAARGARAAYCAYYTNGAY---CARAGYGAYATGGAY CARTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNACNGARGAYGAYGGNACNTCNTGYAGYMGNGGN GARAARYTNCCNATH---CCNYTNGCNATGTGGGAYTTYGARCAYTGYGAYCCNAARAAR TGYACNGGNAARAARYTNAGYMGNGCNGGNTTYGTNMGNACNYTNMGNYTNAGYCARMGN TTYAAYGGNYTNATHYTNTCNCCNGTNGGNACNAARTGYGTNGCNCCNGTNGAYMGNGAY ATHGTNGARACNCAYGGNGTNGCNGTNGTNGAYTGYAGYTGGGCNAARYTNCARGARACN CCNTTYGCNMGNATGAARGGNGAYCARYTNMGNYTNYTNCCNTAYYTNATHGCNGCNAAY CCNATHAAYTAYGGNAARCCNTGYAARYTNTCNTGYGTNGARGCNTTYGCNGCNACNYTN TAYATHACNGGNTAYTCNGARGARGCNGARACNYTNYTNMGNAARTTYAARTGGGGNMGN TCNTTYTCNTCNYTNAAYAARGARYTNYTNGARACNTAYAGYAARTGYCAYACNAGYCAR GARGTNGTNTCNGARCARGARAARATHYTNGCNMGNYTNGARGARGAYGGNMGNCARAAY AARATGAARAAYTGGATGGARATGGAYTCNGAYACNGAYGTNTGYAAYCCNAAYMGNCCN ---------YTNTCNGARTCNAGYTCNGARGARGAYACNGARGAYGARAGYGARGAR--- ---------------------------------------------------------ATG GARAARTAYTCNATGGARTGYGTNGCNGCNCAYTCNGAYCCNGCNTTYATGATGGARGTN GCNACNCAYATGGAYAAYCCNAAYTCNATHGCNACNCCNGARTTYATHTGYAARTAYCAR AGYGAYYTNGTNAAYATHGTNGARTGYATGAARGAYAARATHCARGGNTGYATH---CCN GARATGTAYAARCCNYTNATGGARYTNTTYCCNTCNAARGARMGNYTNACNGAYGGNGTN AARTTYATGTGYGAYAAYAARGARGTNYTNCARAAYAARTGYATG------------CAR GAYCAYGTNATGGAYGTNTAYACNTGYTAYATGGGNAARATHGGNCARYTNCARAGYMGN GCNACNACNACNTCNGAYATGAARGGNYTNTTYTGYAGYGTNATHMGNTCNGARGARCAR TGYTTYMGNGAYCAYAARGGNACNTGYAGYAGYGARTAYATHGARGTNATHGTNCARYTN ATHGARAARATHTTYCCNACNTCNTCNTGYGGNAAYTCNGTNGCNAGYTCNAAYAGYYTN GCNAAYGTNYTNGGNAGYYTNYTNATHCAYGGN------------------CARCCNCAR GGNGAYYTNMGNTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CARACNCAYGTNCCNAGYGARGTNTCNAAYYTNGARAAYGTNAARCCNTCNATG ATGGGNGARMGNGARMGNACNATHCARACNYTNCARGAYGARYTNAAYGARYTNMGNACN CARGTNYTNGGNATGGAYGAYMGNCAYGARMGNGARAARGGNCARTGGYTNGARGARAAR AAYAARGTNATHMGNTAYCARAARCARYTNCARYTNAAY--------------------- ------------------------------------------------------------ ------------------------------------TCNTGYTTYTTYATGTCNYTNCAY YTNGCNGCNGTNYTNAAYYTNGCNTGYYTNGTNTAYATGYTNCARTGGYTNCCNACNGCN GARTCNTAYGTNCCNTAYTTYGTNGTNATGGGNYTNTGGGGNGTNACNGAYGGNTTYTGG ACNGCNCARGTNACNAGYYTNATGGGNYTNATHTTYCCNGAYAARATHGARGARGCNTAY GCNGGNYTNMGNATGACNCARGGNYTNAGYGCNGTNYTNATGTTYGGNATHTCNAGYGTN YTNTGYATGGCNGCNAARATHTAYYTNACNATHGGNATHTGYGCNGTNGGNYTNYTNGGN TAYACNGTNATGGARGGNYTNGTNMGNTGYMGNMGNGGNAARCCNGCNGTNYTNYTNAAR CARACNTCNGTNATHGAYAGYACNCARYTNYTNGCNTTYAAYATGMGNYTNAARGAYTCN CCNCARGGNACNATHGTNATHACNAAYGGNGGNMGNTAYGARGTNAAYGTNGGNAAYMGN GTNMGNACNTCNGTNTTYTGGGAYCARGARCCNATGTCNGTNMGNMGNTGYTCNTGGTTY TTYAARMGNGARGGNGAYAAYMGNTAYGTNCCNTAYGAYGARGARTTYTGYYTNAARYTN GARAAYGARTAYAARAARGCNYTNGARACNAAYGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARYTNMGNGAYMGNAARMGNGCN CARMGNCARAAYGTNGAYTTYGCNGARMGNGARMGNYTNMGNGCNMGNGGNMGNATHAAR GCNYTNMGNGARGAYCCNGTNTTYMGNGARGTNGARMGNCARAARGAYMGNGARMGNMGN MGNAARGCNMGNYTNYTNAAYCCNGCNCARMGNATGMGNGARMGNGAYMGNGAYAARTCN MGNAARGCNMGNATGMGNCCNAAYTCNMGNAARGCNGGNTAYGCNMGNATHMGNCCNGAR TTYATHYTNYTNGAYCAYAARCCNAARATHCARACNGARTAYYTNAGYGARGAYACNAAR MGNAARATHTCNGGNGARGARAARCARGCNGARCARGGNGAYGAY--------------- ---------------------TCNGCNGARCCNCCNAAYAARAARCCNAARYTNAARGGN MGNAAYAARCARMGNCCNAARAAYGARMGNGTNGARCARAARGAYAARYTNTGYCCNTCN GTNAARGCNGGNAARGAYTGYMGNTTYGGNGAYAGYTGYAARTTYAAYCAYGAYATHAAR GAYTTYYTNAARAARAARMGNCCNGAYATHGARGARAARTGYCCNGTNTTYGCNMGNGTN GGNTTYTGYAARTTYGGNGTNACNTGYMGNTTYGCNAGYAGYCAYYTNGAYGARAAYCAR GARAAYGTNGTNAAYCARGAYYTNTAYGARMGNATGAARGTNGARCCNYTNTTYYTNAAY GCNYTNAGYGAYGAYGTNMGNACNAARYTNTGGAARMGNAARTAYGAYTTYTCNAARGCN ATGAARTGYGTNAAYTAYGTNCARAARACNTTYMGNAAYGAY------------------ ---------------------------------------------------------ACN GARAGYTCNCARATHAGYGAYCARCCNACNAAY---------------------GARAGY AAYATHTGYCCNGTNAARGARAARGARGAYGTNACNACNYTNACNCCNGARACNGARACN GTNAAYGAYGAYYTNAGYCCNCCN------ATHGCNGGNCCNGCNCARAGYGAYAAYAAR ATGATHATGGCNTAYAAYAAYGAYGAYGTNGCNATHMGNYTNACNCCNMGNGARGTNAAR AARATHGAYTTYCAYAAYAARYTNTAYYTNGCNCCNYTNACNACNGTNGGNAAYYTNCCN TTYMGNMGNGTNTGYAARGAYTAYGGNGTNGAYATHACNTGYAGYGARATGGCNYTNGCN TCNCARYTNYTNAARGCNAARGCNTCNGARTGGTCNYTNATHAARMGNCAYCCNTGYGAR GAYATHTTYGGNGTNCARATHTGYGGNGCNTTYCCNGAYATGATGACNAARTGYGCNCAR GTNYTNACNGARACNAGYAAYATHGAYTTYATHGAYATHAAYTGYGGNTGYCCNATHGAY YTNGTNTTYMGNAARGGNAGYGGNAGYGCNYTNATGGGNAARGTNACNAARYTNGARCAR ATHTGYMGNAGYATGMGNGGNGTNATGGGNGGNATGCCNYTNACNGTNAARYTNMGNACN GGNGTNTTYGAYAAYAARAGYACNGCNCAYAAYATHATHCCNMGNATGMGNGAYGCNGGN GTNTCNYTNGTNACNATHCAYGGNMGNTCNMGNGARCARMGNTAYACNAARYTNGCNGAY TGGGAYTAYATHGAYTAYTGYGCNAGYYTNGGNGGNCCNATGCCNGTNTTYGGNAAYGGN GAYATHYTNTCNTAYGARGAYGCNAAYYTNCARATGGCNMGNAGYMGNGTNTCNGGNGTN ATGGTNGCNMGNGGNGCNYTNATHAARCCNTGGATHTTYACNGARATHAARGARCARMGN CAYTGGGAYATHTCNTCNTCNGARMGNTTYGAYATHYTNMGNTCNTAYACNAAYTAYGGN YTNGARCAYTGGGGNTCNGAYCAYCARGGNGTNGARACNACNMGNMGNTTYATGYTNGAR TGGYTNTCNTTYYTNCAYMGNTAYATHCCNGTNGGNGTNYTNGARCARGTNCCNCARAAR ATHAAYGARMGNCCNCCNTAYTAYATHGGNMGNAAYGAYYTNGARACNATGATGGCNAGY GGNAAYTGYGCNGAYTGGATHAARATHAGYGARATGYTNYTNGGNCCNGTNCCNCCNAAY TTYCARTTYYTNCCNAARCAYAARGCNAAYGCNTAYCAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNCCNYTNGAYGAYCCNAAYGARYTNACN TGYATHAARCCNYTNAGYGAYGCNGTNGTNCARGTNCARACNCCNGARAAYGCNCCNGCN MGNAAYGGNCARATHAARGARTAYCARTAYACNTTYCARCAYGTNTTYGAYGAYTTYACN TCNCARAARGCNGTNTTYGAYAARACNGCNYTNCCNATHGTNGARGAYYTNYTNTGYGGN AARAAYGGNYTNYTNTTYACNTAYGGNATHACNGGNTCNGGNAARACNTAYACNATGACN GGNGTNCCNCARGAYCARGGNATHYTNCCNMGNTGYYTNGAYGTNYTNTTYAAYAGYATH GGNGARMGNCARGCNAARAARTAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYTCNGGNTCNAAYATHYTNGARYTN CARMGNAARGTNAARGAYYTNGARTCNAGYYTNTCNAARAARGGNGAYGARYTNCARCAR CARGCNACNTCNYTNCAYGARCAYCAYMGNCARAARGTNGCNACNYTNAARGARMGNCAY TCNAARGARGTNAARTCNYTNAARGARAARYTNAAYGTNYTNGARCARCARYTNTCNAGY TCNCARCAYAGYGGNYTNYTNCCNGARTCNGAYMGNCCNAAYGTNAGYAGYAAYMGNYTN GCNGARYTNGARAARYTNGCNGCNGCNGTNAGYGARAARGARAARGCNCARAAYGCNMGN ATHCAYYTNGARGGNGTNYTNGARGARYTNCARCARGARGTNGARMGNYTNCARCARGAR CAYGARGCNCAYAAYGAYGGNGGNMGNTCNGARTCNATGCARMGNCARYTNTCNGARYTN TCNCARYTNYTNGARGARTCNCARGARGARAAYAARCARYTNAARTCNGCNYTNGARACN TCNAAYGARACNYTNGCNTCNYTNATHAGYGCNAARGARGARAARGAYGGNGTNGTNGAR MGNYTNGARGARYTNATHACNAGYATHGGNGAYCARGAYTGYCARGARAARACNGCNGAR YTNYTNAAYYTNATHCAYAARGARAAYYTNATGYTNAARGARCARAARACNAARYTNGAR GARCARGTNGTNYTNYTNGARAARTCNTCNTCNAAYCARATGAARGARAARCARTCNYTN YTNGARACNATGGCNACNATGAARTCNCCNACNGTNGCNATHGAYGCNTCNATHACNTCN GARACNGAYGAYACNYTNGAYACNAARTTYACNACNTCNCARGTNMGNCARGARGAYATH GAYGCNGARGTNYTNMGNYTNMGNTCNGCNYTNAARAARATGGGNGARGARTCNTCNAAR TTYGARCARGARAARTCNGAYTGGGTNATGGARAARGARACNYTNGARGAYATHYTNACN GAYYTNCARACNAARTCNAARGARCARGARGAYGARATHYTNTCNYTNAARTCNTCNCAR CARTCNAAYGARAGYCARCARGGNGGNGAY---------TCNGAYTCNAARATHCARGAR YTNGARMGNGARGTNTCNTCNYTNAARGARCARAAYTCNGARYTNGARATHGCNATGGAR GARYTNGAYACNCARCAYTCNGARGCNYTNGCNCARYTNATHAAYCARMGNGAYAARATG GCN---------------------TCNCARYTNACNGAYCARCARTCNGARATHGAYCAR TAYAARMGNGARATHGARTCNYTNATHGCNAAYGAYTCNGARAARCARCAYGCNGARGAR AARTGYCARAARTAYGARAARGARYTNATGGARTGGAARGARAARAGY---GCNGAYYTN ATGGARAARAARATHGTNGARYTNAARGARAARYTNGARAARGGNGCNYTNGTNATHAAY GAYYTNCAYATGGAYAARCARGAYYTNAARGARCARYTNCARAARGCNCARCARGARATH GARGTNAARGTNTCNAARYTNAARCARAAYMGNACNGARMGNGCNGAYTTYGARAARGAR AARMGNGARGTNGARGARAARYTNMGNGARACNGARGARAARMGNYTNGARACNGARGTN GARYTNGARAARTGGCARCARYTNAAYGARGAYMGNCARATH---CARGAYGGNGTNGAY MGNCARGARAGYGARTGYTCNCAYYTNMGNTCNAARGTNGARGARATGAARCAYGARAAR GARGCNATHAARGARGARTTYCARAGYYTNATGGARGGNAAYGAYYTNCAYGGNGARCAY YTNTCNTCNTTYAARGAYTCNGCNTTYCARCAYATHTTYGAYGARGARYTNMGNGTNMGN CARAARYTNGARGARGAYGAYAARATHATHCARGARYTNAARGARTAYATHGARAARYTN MGNGAYGARMGNAARACNYTNAARGARAAYGTNACNGTNYTNAARTCNGAYAARATHGAR TAYGARTCNYTNYTNAAYTCNYTNCARCARGARAARGCNAARTTYGTNGARCARYTNGAY GARCAYMGNGTNTCNYTNGARAAYAARGAYTCNCARYTNGARGARATG------------ ------------AARGGNGAYYTNGARGCNYTNAAYGGNGARAARYTNAARYTNGARAAR AGYYTNGCNGAYGTNAARACNGCNTAYGARAAYCARGAYGARCARTAYGARGARATHAAR ATHGGNAARGARYTNMGNGAYGARAAYGTNGARTCNYTNMGNGARYTNAAYGTNGARATG GARMGNYTNAARAARCARGTNGARGARGCNGARGGNYTNAARAGYTCN------------ ------------------ATHACNGARAARAGYCARGARATHGARCAYYTNAAYAGYGAY AAYGARATHTAYAARAAYGARATHCARTCNATHAARGCNGARGTNTCNMGNYTNGARGGN YTNTGYAARGARAARGAYATHGARATGGARYTNGTNAARGARMGNATGGGNMGNTTYGAR CARGAYYTNTCNGARATGGAYGARTCNGTNCAYACNTCNCARGARGARAGYGARYTNGAR ATHMGNAARAARGARGARGARATHTCNYTNYTNCARACNAAYAAYGARGARYTNGARMGN AARYTNAAYGARATHCARAGYCARYTNMGNTCNAARGCNGARYTNCARAAYAGYAAYAGY YTNGARAARGAYAARACNATHGGNGTNYTNACNAAYGARMGNGAYGGNAAYTTYCARACN ATHTCNACNYTNCARACNGARYTNTCNGTNTCNGARGARAARATHACNAGYYTN------ ------------------------------------------------------------ ---------GARGARCARATHTCNAARGCNAARTCNGARATHTCNTCNAAYGCNAAYGTN AAYAARCAYTTY---------------------------------------YTNGAYGAY GTNAAYGGNAAR------------------------------------------------ ---------------------------------------------------GGNGARATH GARGTNATGGTNAARTCNGTNTCNTCNGCNYTNYTNACNTCNCCNTGYCCNACNTCNGAY GARGTNCCNGAYTAY---------------------------------TCNAAYGCNCAY GGNMGNTTYGTNGARYTNGARAARGARATGGARGARYTNMGNGARMGNYTNATGGARAAR GAYGGNATHYTNTCNGAYYTNCARMGNTCNAAYTCNTCNYTNYTNGARYTNYTNGAR--- AAR------AARACNGGNGGNGAYACNGGNMGNGTNGCNAGYCAYAARYTNGARGCNGAR YTNAARGCNYTNMGNGTNGARMGNGARCARATGGTNGCNGTNGTNAGYGAYAARTCNMGN GARAAYTCNTCNYTNAARTCNGARATHCAYMGNYTNATGGAYYTNGTNGCNGCNGGNCAR GCNGCNYTNGCNAARGTNCARCARGAYAAYGTNACNYTNGARCARMGNCARCAYTCNCCN CCNMGNGARAAY------GARGARGAYGARATGAARMGNGARGCNYTNAAYAAYATGGCN MGNYTNGTNMGNGAYMGNGAYACNGARATHGARGCNYTNACNCARAARAAYAAYACNYTN YTNGCNGTNYTNCARGAR---TCNAAYGARTCNAGYGCNGCNGCNCAYYTNGGNCCNYTN YTNAARGARAARGARGCNYTNACNCARCARATHAAYTCNATHYTNACNGARMGNGARCAR YTNATHTCNTGYGTNACNCARAARCAYTCNGARTCNYTNGCNTTYCAYGCNGARGTNCAR MGNYTNACNGGNYTNYTNGTNGGNGCNCARGARGCNGCNGARAARGCNAARGCNGARTAY GCNGCNYTNATHCCNTCNTTYGARGGNAARAAYCARGCNYTNYTNACNACNCARCARGAR YTNATHGARTGYAARCARAARYTNTCNGAYATHGARATHMGNTAYGGNGARYTNATGCAR AGYTCNGAYGCNCCNTCNGTNGAYGAYYTNGARGCN------------GAYYTN------ ------------------GARAARYTNAARMGNYTNAARGCNGAYTAYAARTCNATGGTN YTNGARMGNGAYGAYCAYATHCARAGYYTNTCNCARAARGTNAARATHGTNGARGAYGCN YTNTCNTCNMGNGARGCNGARTGYACNCAYYTNMGNAARCARYTNGARAAYTCNAARTTY CARYTNACNGGNYTNATGGCNGARATHGCNGAYGTNAARTCNGARAARGARMGNGTNCAR CARAARAGYGAYAGYAARGGNGARGARTCNGTNAGYYTNMGNAAYAAYYTNGAYCARATG ACNYTNACNGTNAARAAYMGNGAYYTNGARATHAAYTCNYTNAARGAYCARATHGCNACN YTNAAYTCNGTNYTNCARAAYCARAARGGNGAYGARGAYCARGTNAGYCARYTNATHMGN GAYCAYGARATGGCNGTNGTNGCNAGYMGNCARYTNCARCARGARMGNGAYMGNAAYGCN ATGYTNGCNGAYCARMGNYTNCARGARTGYGARGCNYTNAARGCNGARGTNTCNTCNCAR AARGAYAARGTNGTNAARYTNGGNMGNGARYTNGARMGNYTNMGNAGYCAYYTNATHGAR ATHGARGARGGNTAYACNAARGARGCNYTNGARGCNGARGARMGNGARAARGARYTNMGN AAYAARYTNGCNGTNGCNGARGARCARYTNYTNTCNTCNTCNTCNCAYGTNCARYTNGCN AGYCARGARTCNCARMGNCARATHGARACNYTNCARGARCARYTNCAYCAYATHGCNTCN CARMGNGAYGCNGCNTAYATGCARGTNGCNACNTCNCARGAYCARTGYCARCARTAYGCN GCNTCNYTNAGYAAYYTNCARYTNGTNYTNGARCAYTTYCARAARGARAARGARTCNGCN GTNGCNYTNGARACNGARAARTAYCARGAYCARGCNAARTCNYTNAGYTCNAARGTNGCN GARYTNCARAARGARYTNGARGCNACNMGNAGYGAYYTNACNGARGCNYTNGAYGGNYTN GARGCNGCNTCNMGNYTNAGYGARCARYTNGAYMGNAARGARGARGCNYTNGCNGCNYTN AARGARGARGTNCARYTNMGNGARCARGCNYTNAARGGNGCNGARGARGARATHGCNAAR YTNAAYTCNAGYAARGARGCNAARGTNGAYAARATGYTNATGCAYAAYATGGTNYTNACN TGGYTNACNTCNCCNGARAARAARMGNAAYGARATHGTNCARYTNATHGGNCAYGTNYTN GAYTTYAGYCARGAYGAYTTYTCNAARATHGARTCNGCNCAYAGYCARGAYAAYYTNTGG ATHGGNTTYTTYAARMGNTCNGCNCCNAARTCNTCNCCNACNACNACNAGYAARGTNGAY CARTCNTTYTCNCARYTNTTYGTNAARTTYYTNGARAARGARTCNACNCCNGCNCCNACN CCNGTNGARYTNCCNGTNGARGCNATGGCNGCNGARGCNCARCARMGNCAYAARATHGCN TTYAAYCCNTTYATGGCNCCNMGNCAYGTNACNCAY---GGNAAYGARGCNCCNGGNTCN TCNGGNTCNTCNTCNCAYYTNYTNATHCCNCAYGAYAGYCCNCAYCCNTCNCCNYTNTTY GCNCCNGTNACNAGYGTNTCNAGYTCNGGNGARAGYGCNATHYTNAARGAYGTNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TCNYTNGARGARTCNAGYTGGMGNCARGARATGGARATHTAY AAYACNGGNATGYTNAGYCAYGARAAYATHYTNGTNTTYCAYGCNTCNGAYACNATHGGN MGNTTYTCNTGYACNCARAAYYTNYTNATHGTNCARTAYCAYCCNAAYGGNTCNYTNTAY GAYTAYYTNCARMGNAGYGAYATHGAYYTNGARGARATGYTNATG--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGYTNTTYAAYYTNGARGAYTGGCARCARGGNATGGAYYTNYTNTGYGARGAYYTNAAY MGNAARYTNGTNTTYMGNGARCAYTTYGAYTGYYTNTCNAARTAYGCNACNMGNATHTCN MGNTGYATHATHGAYAARACNCAYYTNTTYMGNAARGCNATHCAYCARGCNGGNATGTCN ACNCAYAARTCNYTNCAYGAYATHACNTGYAAYTTYGCNGARAAYATHGTNAAYTGYYTN GARMGNCCNYTNAGYAARMGNTGYCCNGTNMGNGTNGTNGAYACNATGGTNACNGCNYTN CAYMGNTTYYTNCCNCCNGCNTGYGCNCCNYTNCCNGCN------------ACNGAYGTN AAY---------------------AAYGCNACNGTNYTNGARGCNGTNATHYTNGARGGN GGNGGNGGN--------------------------------------------------- ---------------GARCARACNAAYTAYTAYGARYTNAARAGYAARATHGTNGTNGGN AGYCCNGTNCCNGARATHAARAAYGCNAGYATGCCNATGMGNGCNAAYYTNAARCARCAR YTNCARMGNCARCARYTNTAYGAYCARGARAARMGNCARAARGGN---TCNAARAAYAGY CAYATHACNGGNTCNATHGGNATHAAYGTNCCNCAYGTNGTNGARTCNTCNTCNGTNCCN TCNACNGTNYTNCARGTNCAYACNCARYTNCARCAYCCNACNAARTAYCAYGTNMGNCAR AAYCARAARMGNCARGTNCARAAYTTYYTNCARGARCARCARGGNAGYCAYYTNCCNATH CARTCNYTNCCNTCNAAYYTNACNCARYTNGCNTCNCCNTCNTCNTCNCARCARCARCAR CARCARCAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARYTNAAYGAYGTNAARTTYGCN GCNTAYMGNACNTCNATGAARYTNMGNTGYGTNCARAARGCNTGYTGYYTNGAYYTNGTN GAYYTNGAYGGNGCNATHAARGTNTTYAGYCARAGYACNYTNYTNYTNAAYAAYGARACN YTNYTNGAYGTNGGNGAYATGATHAAYATHYTNYTNGCNYTNTTYGAYAARATGGARAAR CARMGNAARGARGCNGTNAAYATGYTNCARAGYGTNGAYATGACNYTNAAYTGGYTNYTN AAYGTNTAYGAYAGYGGNMGNATHGGNAARATHMGNGTNYTNTCNTTYAARGTNGCNGTN GTNYTNYTNTGYMGNGCNAARYTNGARGARAARTGGAARTAYYTNTTYMGNCARGTNGCN GAYGGNTCNAGYCAYYTNGAYGCNAARAARYTNGGNYTNYTNYTNCAYGAYTGYGTNCAR ATHCCNMGNCARYTNGGNGARATHGCNGCNTTYGGNGGNAGYAAYATHGARCCNAGYGTN MGNAGYTGYTTYGARAARGCNAARAAYAAYTCNTCNATHGAYGTNAAYAAYTTYATHGAY TGGACNTCNGCNGARCCNCARTCNATHGTNTGGATGCCNGTNYTNCAYMGNYTNGCNGCN GCNGARACNGCNAARCAYGARGCNAARTGYAAYATHTGYAARGARTAYCCNATHGTNGGN TTYMGNTAYMGNTGYYTNAARTGYTTYAAYTAYGAYYTNTGYCARAGYTGYTTYTGGTCN GGNMGNGTNTCNAARAGYCAYMGNYTNACNCAYCCNATGCAYCARTAYAGYYTNGCNACN ACNACNGGNGARGAYATGGCNGAYTTYGTNAARYTNATGAARAAYAARTTYAARTCNMGN MGNTAYMGNAGYMGNCCNCCNAARAARGGNTAYYTNCCNGTNCARAGYATHATGGARGGN AGYACNATHGARACNCCNACN--------------------------------------- ---------------------------------------------------ATHCCNTCN ACNCCNGAYATGGGNTAYMGNMGNATGAAYGGNTCNGCNTCNCCNGAYACNGARGARCAY MGNYTNATHCARCARATGTGYCARTCNYTNAAYGGNGAYGTNACNACNCCNAAYCCNAAR AGYCCNTCNCARATHYTNGCNTCNYTNGAYTTYGAYCARAARCARGAYATHAAYGARATG ATHCAYAGYYTNGARGARGARCAYMGNGCNYTNCARGAYGARTGYAAYMGNYTNAARGGN ATHAARGCNAAY------------------------GGNCAYTCNATHGAYGGNAGYAGY TCNGGNACNGARTCNGTNMGNGAYGCNGARYTNATHGCNGARGCNAARATHYTNMGNCAR CAYAARGGNMGNYTNGARGCNMGNATGCARATHYTNGARGAYCAYAAYMGNCARYTNGAR GCNCARYTNCARMGNYTNMGNCARYTNYTNGARCARCCNCCNTCNGARMGNGAYMGNGCN GCNATHCCNTCNCCNTCNMGNGTNACNCCNGCNYTNACNCCNTCNTCNTCNTAYCAYGGN TCNCCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARATGACNAARAARACNAARAARAARGARCARAARATHGAYTCNGARGARAAR CARGAYGAYGAYACNGARCCNGAYMGNAARCARMGNAARAARAARAARATGCARAARGCN GARTCNGARCARGARCARGAYGAYGAYGARGARYTNGARAARTCNGARAARAARGCNAAR AARAARGCNAARGARGTNTCNTCNTTYGGNGTNGTNGAYACNGARYTNYTNAARGARCAY GGN---------------------GGNGARGAYGTNAARGCNAARAARACNAARAARMGN AARCCNAAYCARGTNAAY---------------------------------------MGN GCNYTNGAYTAYYTNTAYYTNTGGAARAAYGAYTTYAARTCNTGGAARTTYAGYAARYTN TAYCARGCNMGNYTNATHAARATHYTNTAYAAYGAYTCNCARYTNCCNGARGARGAYTTY GARACNTGYYTNCARTAYTTYTCNAARAGYCARGGNAARGTNMGNGARCAYYTNAARTCN GARGCNATGAAYTTYATHAAYGARGAYGAYGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGGCNGCN CCNTGYAAYAARTCNCAYTGYYTNCCNTGYGAYGAYTTYATGAARTTYCARGAYGCNYTN AARAARYTNMGNATHATHGAYGAYMGNATHATHCAYGCNYTNAAYAARAAYATHCCNACN CARTCNTTYCARCARCARGTNAAYGTNACNTCNAAYTGYAARCARATHTAYGAYGAYATH CARACNTCNCAYAAYCAYMGNGARAARTCNATHCARCARTGYATHMGNYTNGTNAGYGAY GAYGTNAARAARYTNAGYGAYAARMGNCARCARGAYCCNGAYAAYYTNGAYGTNATGAAR AAYYTNMGNAARGARCARACNAARYTNMGNYTNATGCARCARGARATGAAYGTNGARGAR GTNGTNAARGAYMGNACNYTNAARGTN---------------------------TAYYTN TGYGGNYTNAAYGGNATHAGYGARAARGARATHYTNTGYYTNGGNCAYGGNCCNTTYTCN CAYACNTTYGARCARATHATGAARGAYAAYGGNAAYAARGAR---GARTTYCAYCAYGAR AAYCARAGYGTNAARATGYTN------------------AARAARATHTTYGARAGYYTN GARGAYYTNCCNMGNTAYGGNATHGARGARAARGARAARCARYTNATHAARGAYATGATH ATHGGNCARGARAARACNATHAARGGNGARCARAARMGNGARAGYAARGARAARYTNAAR MGNTTYYTNTAYGARATHGTNGCNAAYAARTGYACNGGNATHGAYTGYGAYAARTTYGAY TAYYTNYTNMGNGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GCNAAYGTNACN GAYATHAARAAYGGNAARATHGCNTCNCAYYTNGARYTNGTNAAYCAYACNGTNMGNGAY ATGYTNAAYGARYTNAARMGNAARGARYTNGCNMGNYTNACNCARYTNGCNMGNYTNCAY ATGAARGCNAARTCNGGNATGAARAAYTTYGARATHCCNGAYCAYYTNGAYYTNGGNAAY CARCAYACNTTYGARGTNAARGAYYTNGARAAYYTNATHAARAARACNACNTCNGAYYTN GARMGNYTNGAYGARCARMGNMGNAARGARTTYAARGARTAYGARATGGARAARAARTTY GARGARGARGARCAYYTNAARCARYTNAAYGARGAYGARAARAARAARGARAARGARAAR YTNGARGARYTNAARAARAARCAYAARGAYCAYCCNAARYTNCAYCAYCCNGGNAGYAAR GAYCARTTYGARGARGTNTGGGAYAARGAYGAYCAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGGTNGCNTTYGGNYTNCAYYTNGGNGCNTGY TCNGCNTGYYTNGCNGTNCAYMGNGAYGGNAARACNGARGTNATHGCNAAYGAYYTNGGN GAYMGNGTNACNCCNACNGTNGTNGCNTTYACNGAYCAYGARATHTCNGTNGGNGCNGGN GCNAARCARGGNGCNGTNMGNAAYGCNGCNAAYACNGTNGCNCAYGTNAARCAYATHGTN GGNAGYGTNAGYAAYGAYGCNCARGTNAARGARTAYACNCARAAYCAYCARGTNGAYGTN AGYGAYCARAARGGNGCNGTNATHTTYAAYGTNGARTAYCARGGNAARAARGTNCARTAY ACNCCNAGYAARATHYTNGARYTNATHTAYAAYAARATGYTNGARACNGCNCARAGYCAR AGYGGNGGNGGNAARAAYGAYGCNGTNYTNGCNGTNCCNTCNAAYTTYACNCARCAYCAR MGNAAYATHYTNAGYGARGCNGCNATGAARGCNGGNTTYAAYGTNYTNMGNYTNATHAAY GARCCNTCNTCNGCNATGYTNGCNTTYGAYGTNGGNCARTTYGAYGARTCNGARCARGAR TTYAARACNYTNGTNTAYMGNYTNGGNGGNACNTCNCAYGAYGCNACNYTNGTNAGYGTN CARCAYGGNATGTAYTGYATHYTNGCNAARGCNTCNGAYAAYCARTTYGGNGGNGAYAAR YTNTCNGARGTNYTNCARGAYTTYYTNGCNACNGARTGYAGYMGNCARTTYMGNTGYAAY GTNAARGARAGYAARMGNTCNATGAGYAARYTNAARYTNGCNGCNGARMGNTGYAARCAY TCNYTNAGYTCNATGTCNAAYGCNCARTGYAGYGTNGARTCNYTNTTYGAYGGNYTNGAY TTYTCNTAYAAYGTNTCNMGNGCNMGNTTYGARAGYYTNTGYATGCCNYTNYTNTCNCAR TGYACNCARYTNGTNCARGARGTNYTNAAYAGYGCNGGNTTYGCNAARGAYGAYATHTCN AARGTNATHYTNTGYGGNGGNGGNGCNAARCCNCCNATGGTNAARAARGTNATGGGNGAY TTYYTNCCNTCNTCNTCNYTNYTNAAYTCNATGCCNGARGAYGARATHATHGCNATHGGN GCNGCNAARGARGCNGCNYTNYTNGARGGNGAYGAYGAYGAYAARGTNAARGTNGAYGTN GARGGNTCNAAYGCNTTYAARTCNYTNTCNAARGCNATHTGYATHAARGTNAAYTCNGAR GARYTNAGYGTNATHYTNCCNCARAAYTGYYTNATHCCNTCNMGNMGNCARCAYACNYTN ACNYTNCCNACNAGYCARACNTGYGTNAARATHGARATHTTYGARGTNCARGARCCNATH ACNTCNGARTCNGARGCNYTNYTNYTNGCNAARATHGTNYTNMGNGAYYTNCCNCCNGGN TCNAGYATHAARACNAGYTTYCAYYTNACNMGNCCNACNCCNCCNACNTTYCCNAAYGCN TTYAGYGTNTCNTTYAAYGAR------------------ATHGARCARYTNTTYGGNAAR GTNYTNAGYACNAAYAAYGGNACNTGGTAYTTYGAYTTYTCNAAYMGNMGNGCNMGNTTY GAYCAYAAYMGNGGNCARACNAAYAAYTTYTGYGAYTTYCARAAYYTNAGYCCNAARGAY CCNAARGCNGAYTGYCARYTNTTYTTYACNCCNACNGARGAYATGTTYGTNTAYTAYCCN GGNGCNAARACNTGYTGYMGNYTNTGYGGNAARGAYGARGGNTGYACNATHYTNAARCCN GAYTGGYTNCAYCARGGNTCNAARYTNATHTCNGTNGARCARATHAAYGGNATGACNTGY TAYGGNTGGGCNAARCARGGNGCNGTNGCNGCNGCNGAYACNTGGTTYGCNACNGCNGAY GGNGTNCCNTGYMGNTAYCAYGARGTNGTNYTNCAYATHAAYCAYAAYYTNACNTTYYTN CCNYTNACNTAYAARATHGGNCCNCARGAYCCNGCNYTNTTYGAYGTNCCNTCNGGNTGY AAYAARACNTGYCCNCAYCCNTAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNCCNAAR TGGGGNGARACNYTNCCNCARGAYTTYTTYGAYMGNYTNMGNYTNTGGGARGARGARMGN AARCARCAYAARCARGARYTNAAYGARAARACNYTNAARGAYATHAARGAYAAYYTNGAR AARAARYTNGCNGGNCARCAYAARYTNAGYAARMGNGARGARCARATHTAYGAYGCNYTN AARGAYGTNAGYYTNCCNGCNYTNTTYATGCCNTAYAARACNGGNAAYATHTTYAAYCCN MGNGCNCAYCAYTAYTTYCAYCCNACNGGNTCNTCNGAYGTNMGNYTNACNCARCCNCCN TCNATGTTYACNYTNCCNCCNYTNCCNAAYAGYAARYTNTCNGTNGTNAAYYTNTTYGAR YTNAGYAARATHTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GGNCCNACNTCNTGYACNATHMGN YTNACNTCNCARTCNCCNATGCCNGGNGTNCARYTNMGNYTNACNATHGGNGCNATGAAY ATHYTNGAYTGYAAYACNCARYTNACNATHTAYGAYGGNGARGAYATHGAYMGNYTNGGN TCNTAYGAYTGYMGNAAYAGYCARAAYACNAAYMGNMGNCCNYTNGTNACNACNGGNGAY ACNGTNTCNTTYATHTTYACNMGNGAYAAYCCNGAYAGYTAYAAYTTYAAYATHGARGTN ACNGTNACNCCNATHMGNAGYGAYGTNGAYCCN------GAYAAYAAYTAY---AAYTTY TTYAGYTTYCARAARTTYGARCARGARGCNATHGTNGGNATGATHGGNGGNTTYTAYGCN YTNATHATHATHATHTGYATHGTNGTNTGYTAYTGYAAYTTYMGN---TAYMGNGGNYTN AAYAARAARTGGGARACNCAYCARYTNGAYACNATGAARACNGARACNACNTTYGAYGGN MGNAGYCARGTNTCNCARCCN------CCNTGGTCNGTN---GCNAGYCARAGYMGNGGN CCNACNAGYACNTAYGARMGNTCNTAYACNGARCCNTAYTCNMGNAARGGNGCNCCNMGN ---AGYGARGAYGGNTCNAGYGTNGTNTAYGAYCAYGAYGARAARTTYCARCARMGNAAY YTNATGAAYGAYGARMGNGAYMGNCAYMGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR GARAAYMGNTTYAARMGNACNGCNGARGCNYTNCARAARTCNGGNYTNTGGGAYATHGCN ATGAARACNGGNCAYYTNATHAARMGNAAYCARGARYTNCARAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CCNATHCCNCCNMGNTGG---YTNCAYTGYCCN MGNAARAGYCARGTNATHCARGGNAARTTYATHGCNTTYAARACNCCNYTNGAYTCNMGN TAYGAYGGNCARGTNCCNTTYGARAAYMGNTGGACNATGGAYATGYTNTTYAAYTCNYTN AARATHTCNGGNMGNAARYTNGGNYTNATHATHAAYYTNTGYAAYACNGAYMGNTTYTAY AAYCARAARGAYYTNGARAARTTYGARTGYAGYGTNATHTCNYTNMGNTGYAARGGNMGN GARACNCCNACNACNGARCARACNGARACNTTYGTNGAYATGTGYGARAARTTYAARAAR CCNYTNGARATHATHGGNGTNCAYTGYACNCAYGGNTTYAAYMGNAGYGGNTTYYTNATH ATHTCNTAYYTNGTNGARAARYTNTCNTGGAGYATHGARGCNTCNGTNMGNMGNTTYGCN CARGAYMGNCCNACNGGNATHTAYAARCARGAYTAYYTNAAYGARYTNTTYGARMGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CARGARGCNGAYAARYTNATHAARCAY TCNCARGAYGARGAYATHTAYAARGARGGNTCNGCNCCNGTNTTYGAYGARYTNTCNAAR ATGMGNGGNATGATGACNYTNATGMGNCCNMGNGGNTCNACNGTNMGNYTNACNTGYAAR GTNAGYGGNAAYCCNGARCCNCARGTNCARTGGTAYAARGGNTCNGARYTNTAYAAYCAR MGNMGNGCNCAYTCNACNYTNAARYTNTAYCARGTNACNGGNAARGAYAGYGGNMGNTAY ACNTGYGTNGCNAGYAAYMGNYTNGGNCARACNAAYTTYACNTAYAGYGTNCARGTNATH GAYGARATHACNCARGCNMGNYTNATHGCNCCNCAYCCNATGAAYAARACNGTNAAYGTN GGNGARTCNGTNTCNTTYCARTGYTTYATHGARAGYGTNGTNAARCCNMGNGTNCARTGG YTNAARGGNGTNGAYGTNTCNGAYGARAAYACNGAYCCNAAYGTNAARYTNATHCAYTAY AAYCARCARACNYTNATGGTNYTNAARGGNGCNGGNATHCARCARGCNAARCCNGAYGGN TCNTAYYTNAAYAARYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNATH------------------------ ---------------------------------------------------AAYACNATG CCNYTNACNCAYMGN------------MGNYTNYTNAGYAARGCNYTNAARATGCCNTGY MGNGARMGNAARYTNGTNAARGARGCNYTNYTNATHMGNTAYACNGAYGTNGCNYTNAAR MGNGARGGNATHGAYAAYYTNACNGAYGAYGAYYTNGAYMGNGCNTGYGCNTGGMGNGGN YTNAAYCCNGARGGNATGGAYMGNACNTCNAARYTNACNTAYYTNAAYMGNTGGACNGAR ATHACNGCNCARGTNCAYCARTCNAGYATHTCNYTNYTNYTNCAYYTNCCNATHYTNYTN TCNTAYTGYCARCCNTCNAAYAARAARATHATHGGN------------------------ ------------------------------------------------------------ ---------------------TGYATHAAYAARYTNYTNTCNYTNCARAAYCCNYTNTCN GTNYTNCARGGNGAYAAYYTNCCNYTNAAYAARATHTGYAARYTNATHCAYGTNAAYGAY AAYAAYAGYACNGCNACNGARYTNGARAARTGYTCNTAYAAYGARMGNAGYGARATHATG MGNGAYATHGARATGCAYATHAARGAYAARYTNGARAAYAARGAYAAYTGGCARAAYGTN GCNGTNTGYYTNGARAAYAAYTAYGGNGAYAGYGARMGNTCNACNTAYATHMGNGAYATH TGYGGNATHGTNGARMGNACNGGNGARGTNTGYMGN---TAYGAYACNCAYAARCARGTN GARAARTTYGTNAAYGARCARATHGARCAYYTNCARTGYACNTGYAARGCNYTN---MGN TCNCAYACNGARGARCAYGAYCAYAGYYTNTCNACNGCNGTNATGGGNGCNYTNGGNGCN GCNGCNTTYYTNATHYTNTGYATHGTNYTNGGNGTNGTNTAYTAYTGYGTNAARAARMGN CARATGAARAARAARAARAARGGNCCNAAYGTNATHTAYYTNCCNGCNGCNAAYTCNGAY AAYTAYCCNGTNTAYCARGARATHTTYGAY---------CARMGNTCNACNCCNTCNAAY CCNCCNGCNYTNCCNAGYMGNTAY------------GGNTCNMGNCCNYTNCCNGGNCAY CCNATHGAYGARGCNGARTAYYTNGARCCNGTNCARGCN---------GCNAAYAGYTTY MGNTCNAARGCNCCNYTNCAYGGNYTNGTNAAYAAYCCNGGNTAYCAYGTNGAYYTN--- ---CCNCCNGARTAYAGYGARACNGAYCARATGTAYGARGAYGCNATHCCNYTNAAYCAR GARGAYGGNAAYGTNTAYATHGAY---------------CCNATHGTNACNCCNAARGAR GAYGGNGAYGARGAYTCNAGYYTNCCNGAYCARTAYCARCCNYTNCARGAYATHGARACN ACNGAYACNGAYMGNAARYTNGGNCCNGAYCCNGCNAAYMGNACNAARAARGAYGAYMGN GTNACNGARTCNGARTAYTTYGARYTNGARATGYTNGARGARGGNAGYTTYACNATGGAR AARAARGCNATHGCNMGNCARTCNCCNGCNCCNGGNCARTGYMGNAAY---GGNGCNGTN GCNGARMGNAARTCNGAYTTYACNCCNAAYMGNMGNGGNAAYAAYMGN------MGNTCN GCNTCNAAYGGNGTNGCNAARCCNCARGAYGGNCARMGNCCN------AGYCCNAAYCAY AARTGGGAYAARTCNATHGGNAGYMGNMGNCARMGNCARMGNAGYGGNTAYGAYTAYMGN CARMGNGARGARGTNGARGARCAYGAYGAYGTNTTYGAYGTNYTNAGYACNGGNTCNMGN AARGGNAAYYTNAAYCAYYTNYTNAAYTTYAARTTYYTNCCNMGNMGNCARAGYCARMGN GAYGAYTCNMGNTGGMGNAGYTAYTAYAGYTCNCAYGGNCARGGNGGN------TAYMGN AARMGNAARMGNTAYAARAARGARCARTTYYTNCARGCNAGYTGYCARTTYGTNGTNMGN GAYACNGGNGAYTAYACNGARCARGCNATHAGYTCNGAYGCNYTNGTNGAYTGGAAYYTN GTNGARYTNGTNMGNAGYTTYTCNACNGARAGYGTNAAYTGYCCNATHTGYYTNGARATG CCNACNGCNGGNAARATHACNAARTGYGGNCAYACNTAYTGYTGGGCNTGYATHYTNCAY TAYYTNAARYTNGGNGARGGNGTNGCNMGNAARTGYCCNATHTGYTAYGARACNGTNGAY ACNGARGAYYTNAARAGYGTNCARTGGATHGARGTNCCNAAYTTYAARGTNGGNGAYACN ATHGARATGMGNYTNATGAARAARACNAARGGNAGYGTNATHACNYTNCCNAARGAYCAR TGGGARGAYMGNATGGGNMGNCCNATGAAYATHCARGAYGGNCCNAAYACNGARTAYATG AARYTNYTNGTNGCNTCNTCNGAYCARATHCARGTNGARGTNATHGARATGGARMGNGCN GCNYTNACNGTNCARYTNGARGTNGCNGARGARTCNGARGCNTGYTTYATHCARATGGCN YTNGARTAYYTNGARGCNMGNGARAARTCNYTNAARGCNCARTCNAARCAYAARAGYCAR ATHCCNGGNATGTGGTCNAGYAAYGCNGAYAARGCNCARGAYGARGTNGARGTNGTN--- ------------------------------------------------------------ ------------------------------------CCNTTYCCNACNCCNGCNGTNCAR GARATG------------------------------AARAAYGARACNACNGAYTTYTCN ------------------------------------------------------------ ------------------------------------------------------GCNGAY GTNGAYTCNCARTCNTCNMGNCARMGNAAYGAYAAYGARTGYTCNYTNTCNTTYGGNTCN CCNCCNTCNCCNTTYCCNYTNYTNCCNGAYCARGARGTNAAYCCNGGNCCNYTNAGYYTN GARGARACNGCNGAYCAYYTNGARYTNCCNATHGAYCCNAARATGGCNCCNCCNTTYACN MGNAAYTCNTTYAAYYTNAAYGCNAARGAYGAYTAYATHTTYTTYCARGCNTCNACNGGN CARCARATHTAYYTNAAYTCNYTNAAYGCNCARTGYATGGCNAARGARTAYGGNTCNYTN GARGAYAGYCCNACNACNATHCARGGNTCNATHGTNGCNATHGARMGNATHTTYATGACN GARGAYGTNMGNAARMGNYTNMGNTAYYTNGAYCAYATHCCNYTNACNTGYGARGTNCAY ATHGTNGARYTNAARYTNAARCCNCCNGTNGTNAGYAARGARACNYTNAARTTYTTYGAR GCNGCNTTYGARAARAARMGNAARCARMGNCARCARAARGARMGNGARGAYMGNMGNMGN GAYAARAARATHGARATHGARCAYAARAARAGYTTYGGNATHTAYCCNGARGTNCAYATH CCNYTNGAYAGYYTNGARCARTTYCCNTCNCAYYTNTCNGCNAGYATGGARTTYYTNGAY TCNATHMGNCARTGGYTNMGNMGNTCNTAYAAYGTNGAYGTNGCNGARGAYTGGYTNTCN ACNTGYGTNGARTTYATHCARCARGARACNCARGGNTCNMGNCCNAGYYTNGARGARYTN AARGGNYTNGTNTTYGARCARTGGYTNGGNTCNGAYYTNGGNGARATHGGNAARCCNTCN YTNACNGAYGAYATHTTYACNTGYGARAARTGYTAYYTNAAYAAYGCNTAYCCNYTNCAR ATHATHTCNATHYTNGAYGTNGCNACNCCNYTNTTYGGNCARYTNCARAARTTYCARACN AAYACNTTYTCNGAYACNCARCAYACN---CARCARAAYACNTTYAAYAAYTTYTCNGCN CCN------------------AARCCNTCNMGNATGYTNAARYTNGARYTNACNGAYGGN ACNMGNACNGTNCARGCNATHGARTAYMGNCCNATHCAYTCNYTNAAYGCNGAYYTNCCN GCNGGNACNAARGTNATHATHAARGGNAGYGTNYTNTGYMGNMGNCARTGYYTNYTNYTN CARCARGAYAAYGTNTGYGTNYTNGGNGGNGARGTNGAYGAYYTNATGGTNGTNTAYAAY CCNYTNGTNAAYYTNCARACNGARATGGAYAARAAYMGNATGGAYAAYAAYGARTTYAAY GAYGARGGNAAYAAYGAYCAYATHGAYGARTAYTAYCAYGGNGARGAYATHYTNAAYCAR ATGAARGAR---------GAYGARGARAAYATGAARGARACNAARCCNCCNACNGCNCCN ACNAAYATGGTNYTNTTYTAYACNTGGATGATHYTNGTNATHYTNATHATGGTNATHGCN GTNTCNACNTAYCARGCNAARTGYAARGGNYTNYTNTCNGGNGGNAAYMGNCARCCNATG MGNGGNGARGAYMGNAARMGNYTN------------------------------------ ------------------------------------------------------YTNTTY MGNYTNMGNGCNGTNAGYCAYAGYTGYATGTGYYTNGTNGAYACNCAYYTNAGYYTNCAR TTYCAYYTNAAYATHTGYCAYYTNGARAARAARYTNACNCCNGCNGCNTTYTCNYTNATG ACNAARGAYAGYMGNTGYYTNAARACNYTNYTNYTNMGNGGNGCNAARTAYGGNYTNAAY AAYGARGTNTTYYTNCCNGTNYTNTCNAAYAAYCCNMGNYTNGARAARATHGAYATHAGY GGNTGYACNTCNYTNTCNGGNTGYGTNYTNTAYGCNATHGGNGTNAAYTGY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR GTNGTNYTNTAYAAYTAYTAYATGAGYTCNTGYAGYTGGMGNGTNMGNATHGGNYTNGCN ATHAARAARATHCCNTAYGARTAYGARGTNGTNAAYYTNGARACNTCNCARCARATGACN GAYGARTAYAARAARGTNAAYTCNTTYGGNTAYATHCCNACNYTNAARATHGAYGGNYTN ACNYTNACNCARTCNYTNCCNATHYTNGARTAYYTNGARGARMGNAAYCCNGARCCNGCN TTYYTNCCNAARGAYAARGCNGAYMGNGCNCARGTNMGNGCNATHGCNGARATGATHAAY AGYGGNATHCARCCNYTNCARAAYYTNMGNGTNACNCARAARGCNGGNGARACNGARGCN GARTGGGCNAAYCAYTTYGTNACNGCNGGNATGGARGCNYTNGARCCNGTNYTNGARAAR ACNGCNGGNATHTAYTGYTAYGGNGAYCARGTNACNYTNGCNGAYYTNTGYYTNGTNCCN CARGTNTTYTTYGCN---AAYMGNTTYAARGTNGAYATGTCNMGNTTYCCNGTNATHGCN MGNGTNAAYAARGCNYTNGARGTNYTNTCNGTNTTYAARGTNGCNGAYGCNMGNMGNCAR CCNGAYACNCCNGARGAYYTNAARATHGARATGGARAAYGCNGAYGCNGCNGTNYTNTCN YTNTGYAARGAYGTNTGGATGTGGMGNATHTCNGARAGYCCNGARYTNGCNACNTTYTGY GGNTTYTAYCARGAYGAYGAYAARTGGGAYGAYATHAGYGARGARGCNTAYGCNMGNMGN GARGTNAARGTNMGNGARTTYYTNAARGCNGCNGARGCNYTNGAYGTNAARGAYTGYAGY CCNGARGTNTCNYTNAGYTAYAARYTNYTNYTNGCNGAYATGAARYTNTAYYTNAGYGGN GTNCCNTAYMGNAGYTAYYTNATGCCNATGAAYTAYYTNGARGGNATHCAYACNGAYTGY AAYYTNACNGTNTCNTAYATGAARTTYGARGARGARAARGAYTTYCARAAYYTNAARGCN MGNYTNGARAARYTNCCNTCNMGNGTNGARTCNGTNATHTCNGTNTCNAARMGNGGNGTN GARCARGGNATHGTNAGYCCNGTNCAYTCNGTNCARGAYATHCCNGGNCARATHGAYGTN ATHYTNGCNACNAARATHGARGAYTGGGGNYTNATGACNCCNTTYAARGARAAYAARTGY GGNATHGAYGCNGARGTNTTYCARAARYTNAARACNCARTGYTGYGAYATHATHCARTCN TCNATHATHCCNGCNTTYAAYACNYTNAARACNTAYATHGTNGARGAYTAYATGAARAAY GTNMGNCCNAARGAYGGNGTNAAYTCNYTNCCNAAYGGNGAYGARTGGTAYAARCAYTGY YTNAAYTTYCAYYTNACNTGYTCNATGACNCCNCARGARGTNCAYGAYYTNGGNYTNAAR GARGTNGCNMGNATHACNGCNCARATHATHGCNYTNGCNAARAARGARGGNYTNCCNGAR ACNATGCCNGARYTNYTNGARGCNATHGARAARMGNCARGCNAAYTCNTTYAARACNCAR GAYGARGTNYTNAARTAYGTNGARAAYYTNTGYTAYAARAARATHMGNCCNAARATHAGY GAYTAYTTYAARGGNYTNCCNGAYATHAARATGAARATHCARYTNACNCCNGCNTAYTCN GCNTCNGCNCCNGGNGGNTAYTAYYTNAAYGGNACNCCNGAYGGNTCNMGNGAYGGNTCN TAYTTYATHAAYGCNAAYAAYYTNGAYTCNTGYYTNCCNTAYGCNYTNCCNGCNYTNAGY YTNCAYGARGGNGARCCNGGNCAYCAYYTNCARGGNATHTAYTCNYTNGCNGCNTCNCAY YTNCCNGAYTTYMGNMGNTAYTCNGARGAYAGYAARTAYTAYYTNGCNCCNTGYAARTTY TCNTTYAAYACNGGNTAYACNGARGGNTGGGGNYTNTAYTGYGARGCNYTNGGNGARGAR ATGGGNGTNTAYTCNGAYAAYATGGARATGYTNGGNMGNTAYAAYATGGARATHTTYMGN GCNGCNMGNYTNGTNGTNGAYACNGGNATHCAYGCNTTYGGNTGGACNAARCARAARGCN GTNGARTAYATGAAYGARCAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGTCNGAYAARYTNACNACNMGNGTNATHCARGTNACNAAY ATHGCNCCNAGYTGYTCNAARGARCARYTNMGNACNYTNTTYGGNTAYYTNGGNMGNATH AARGARYTNGARATGTAYCCNCCNGAYGGNGCNGAR---GGNGTNGTNACNGCNMGNGTN GCNTAYATHGARTTYGARGAYTCNGTNACNACNGGNGTNGCNYTNCAYYTNAGYAGYACN GTNTTYATHGAYMGNGCNATHATGATHGTNCCNGTNATGGAYGGNAARATHCCNGAYGAR AGYTCNGCNYTNCARYTNACNCCNTCNGCNGTNGCNGGNATGYTNCCNGGNCARCCNACN TGGCCNGCNAAYGTNGTNTCNCARGTNACNGGNYTNGGNGCNAAYCARATHATHATGACN AAYGAYCCNMGNYTNACNTCNYTNGGNYTNCCNCARTAYCCNCCNYTNCCNGCNACNACN GAYCCNAGYAARATHGARGARATHMGNMGNACNGTNTTYATHTCNGAYYTNGAYGCNAAR GTNACNCCNGARATGYTNYTNTCNTTYTTYTCNCARACNGGNGARATHAARTAYATHMGN ATGGCNGGNGAYGARAAYGCNCCNACNMGNAGYGCNTAYATHGARTTYACNGAYCARMGN TGYATHGCNCARGCNYTNAGYTAYAAYAAYGTNGTNTTYCARGGNMGNACNGTNAGYGTN AARCAYGCNACNACNAGYATHGTNAARCCNACNCCNMGNTCNGARGCNTCNCARMGNGAR ATHGAYGAYGCNATGAARAARGTNAARGARGCNTCNAARYTNATHTCNGCNGCNGCNAAY AGYGAYMGNGAYAGYTCNMGNTCNCCNGTNMGNAARMGNTCNMGNTCNAARGGNMGNAGY MGNTCNMGNTCNMGNTCNMGN---MGNMGNTCNMGNTCNMGNTCN---CCNMGNMGNMGN MGNMGNAGYAGYTCNMGNTCNMGNMGNMGNTCNMGNTCNMGNMGNMGNTCNCCNAARMGN TCNMGNACNCCNGTNMGNMGNMGNMGNTCN------------------------------ ------------MGNTCNMGNACNMGNGAYMGNMGNMGNTCNMGNACNMGNTCNCCNGTN MGNMGNMGNMGNTCNMGNACNMGNTCNAARTCNAARACNMGNMGNTCNMGNACNCCNCCN AARTCNTAYAGYMGNGGNMGNMGNTCNCAYTCNMGNAGYMGNMGNAGYMGNTCNMGNGAY MGNMGNGAYAARAARGARMGNAARAARAGYAARTCNYTNTCNCCNCCNACNYTNATHMGN GARAAYTCNGCNGCNMGNGAYGARGGNMGNGAYAARTCNCCNATHAAR------GGNAAY TCNCCNAGYCCNCCNMGNGCNAARAARMGNAGYYTNACNCCNAARMGNMGNAGYMGNTCN MGNTCNCCNAGYMGNMGN---AARAARMGNMGNCAYTCNMGNTCNCCNTCN---AARAAR MGNTCNMGNTCNMGNAGYGGNTCNMGNTAYMGNTCNMGNMGNGAYMGNAARMGNAGYMGN AGYMGNGAYMGNAARCAYGAY---AGYAARAARAARAGYGGNMGNGAYAARGARGAYMGN AARAARGAR------AGYAGYTCNAARATHAARMGNGAYTAYGAYGARGARGARAARGGN TTYGCNAGYGAYMGNAGYGAYGARMGNGAYAAYAGYGARGGNCCNMGNTCNMGNGTNGAY TCNCCNAGYGARCCNCCNGTN------YTNGARAARGAYACNGAYAAYCARCCNGTNGAY ATGGAYATGAGYGAYYTNATHMGNACNTTYCAYMGNGAYCARAARGAYTTYYTNGGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CAYATHTGYATGATHAGYCCNCCN CARMGNGGNTCNATGYTNGGNATHAAYAARCCNGGNGCNACNGAYTGYATHYTNYTNAAR GCNCCNTGYGGNGGNMGNGGNGARGGNGGNCCNATHYTNGARYTNATHGCNGGNAARAAY TTYACNGTNACNGTNATGAARAAYYTNGAYCAYTTYAAYCARGCNGCNCCNGGNAAYTTY ACNGTNTCNATHGGNAARGGNGAYGGNCCNTTYAARCARYTNYTNACNTTYCCNGAYGAY GCNGAYCCNTCNYTNACNYTNTAYTCNTAYAAYGTNACNATGCCNGARGAYCAYGGNGAR TTYGTNYTNCARTCNATHTAYAAYACNAAYAAYCCNAARGCNCCNCCNGCNTTYTAYCAR TGYAGYGAYYTNMGNYTNGTNGGNAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARATHTCNCAY ATGATHGCNTTYATHGAYCARGARGCNTCNGARAARGTNGARGARATHGAYYTNAARGCN GARGARGARTTYAAYATHGARAARGGNMGNYTNGTNCARCARTCNMGNGTNCARATHATH GAYTAYTAYGAYAARAARATHAARAAYGTNGARYTNCARAARAARATHCARAAYTCNAAY ATGCARAAYAAYGCNMGNYTNGARGTNYTNMGNAARAARGARGARTAYGTNAARGARGTN YTNGAYGAYGCNMGNGARCARYTNATGAARGTNGCNMGNGAYAAYCCNGARGARTAYAAR CAYYTNYTNYTNMGNYTNGTNATGCARGCNYTNGCNMGNATGGTNGARCARAARGTNACN GTNMGNTGYMGNMGNGARGAYGTNCARATGATHAARAAYGCNATHCCNAGYYTNGTNAAR GARTAYAARCARYTNYTNAARGGNAARTAYTCNYTNGAYYTNGTNGTNGAYGARGARAAR TTYYTNTCNCARGARATHTGYGGNGGNGTNGARYTNCAYGCNATGAGYGGNAARATHGTN ATHGTNAAYACNYTNGAYGARMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGCNGARAGYGAYCARCARTAYACNATHTAYGAY---ACNAAYCARCCNYTNACNYTN ACNGTNAGYAAYGTNAAYCARGGNACNGARGARGCNCARGCNGTNCARAGYATHCARTAY ATHTCNCARGAYGGNGTNCCNGTNACNCARYTNGAYTCNAAYGAYGTNATHCARGTNGCN CARGCNGCNGAYGGNACNTTYCARCARGCNACNACNGCNTTYCARAAYATHCARGGNTCN GTNCARCARCARGTNATHACNAAYGCNGCNTCNGTNCCNATGGTNTCNGCNACNTCNCAR GGNGGNACNATHYTNCARTCNAAYAAYGTNYTNMGNAAYGTNACNCARCARCARACNTCN CARAGYACNCARCARCARACNATHCARACNGCNGGNACNTCNACNGCNCARGTNGGNACN TCNGTNGCNGGNATHCCNCARATGATGTTYYTNAAYCARGTNACNATHAAYGGNCARACN TCNTTYGTNYTNGTNGAYGCNAAYAAYAARCCNATHCARYTNCCNCARGGNATHCARYTN ATHAAYYTNCCNCAYCARCARYTNCCNGGNCARTCNATHCARATGCCNGGNAGYGAYACN GGNGAYGARCCNYTNTAYGTNAAYGCNAARCARTAYCAYMGNATHYTNAARMGNMGNCAR GCNMGNGCNAARYTNGARTCNGARGGNAARATHCCNAARGARMGNMGNAARTAYYTNTAY GARTCNMGNCAYAARCAYGCNYTNAAYMGNACNMGNGGNACNGGNGGNATHTTYGTNGGN CARACNGCNTCNGTNGAYGTNATHYTNGTNGCNGGNAARGAYAARATHCCNGTNAGYGTN TGYATHCCNCARTCNGGNGGNGGNAARGAYTGYYTNACNGTNCAYCAYYTNTGYYTNGCN ATHCARCARMGNACNAAYATHGARCCNCARGCNCARAARATHATHTAYMGNGGNMGNACN YTNTTYAARACNTTYAAYCCNGARGAYTCNAAYGTNAARAARAGYYTNTCNTCNYTNGGN ATHAARAAYGGNGAYMGNATHATGGTNTTYGGNAARCCNACNGTNAAYGARAARTCNACN GAYGARAGYGAYCCNMGNGCNGARYTNATG------AARGTNYTNGAYCARCAYCARGTN AARATHGAYGARATHTGYGTNYTNTGYMGNGAYATGYTNGAYCARATHGGNAARGARAAR GAY---GTNGARGARTGGMGNAARCARMGNAARTTYTTYYTNAGYCARTCNGARTAYTCN ATGCARGARYTNACNMGNYTNGAYGCNACNCCNGGNGAYYTNTCNCARAAYGGNGARTAY AARACNMGNMGNAARACNYTNGTNAAYMGNYTNYTNGARAAYATHACNYTNTGYGAYAAY CARGTNGCNMGNYTNGAYACNTGYATHMGNAARGCNGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYGARGAYYTNYTNGCNCARGGNATHGTNYTN YTNACNGCNGTNCAYGTNGCNACNAGYACNACNYTNGCNGTNGCNYTNTAYTAYATHGCN AARCAYCCNGAYATHCARGARAARYTNCARGARGARATHGAYGCNYTNTCNGARGAYGAR GAYCCNAGYYTNGAYCAYGTNACNCARYTNAGYTAYACNGARCARGTNYTNAAYGARTGY ATGMGNYTNTAYCCNTCNGCNTTYATGYTNATGMGNGARTGYACNGARAGYTGYACNATH GGNGAYATHACNTTYGAYAARGGNAGYATGGTNATHATHCCNACNTAYTCNATHCAYMGN GAYGARAARYTNTGGACNGARCCNGARMGNTTYGAYCCNGAYMGNTTYTCNGGNACNACN GCNAARMGNAAY------TTYTTYCCNTTYGGNGAYGGNCCNMGNACNTGYATGGGNAAY AARYTNGCNYTNATHGARATGAARACNGCNYTNGCNAARATHYTNAARTCNTTYACNATH TCNYTNAARGARAAYGTNTCNTCNCAYGTNACNATHCARGCNATGYTNACN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGGGNAARAARCAYAARCAYGGNAARCAYTCN TCNTCNTCNTCNTCNTCNTCNAGYAGYAGYGAYTCNTCNGAYGAYGARTGGMGNCAYYTN CCNAARCAYGARAARAARATGMGNAARAARTGGAARAARCARATGMGNAARGGNCAYATH GCNMGNGGNACNYTNCCNCCNTGGCARGGNGGNGCNGCNTGGGCNCCNCCNATGAARGGN AARAARGGNGGNAARGTNTAYTCNACNGGNGTNCAY---------------CCNCCN--- ------CCNCCN------GGNTAY---GCNGGNCARCCNGGNTAYCCNGCNCARGGNTAY CCNGGNCARCARCCNGGNTAYCCNCARCARCCNGGNTAYCCNGGNCARCARCCNGGN--- TAYCCN------GGNCARCARCCNGGNGCNTAYCCNGCNCCNCCNAGYTAYCCNCCNGGN GGN---------------TAYCCNGCNGGN------------GGNCARTAYCCN------ ---CCNCCNCCNGCNGCNCARTAYGCNCCNCCNCCNGGNGCNGCNTAYGGNTCNCAYGGN GCNCCNTCNGGNCCNTTYCARGCNCCNCCNGGNGGNGCNTAY---CARTCN------GGN TAYCCNCCNCAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TCN YTNYTNTAYTTYGAYATHCCNGCNMGNGGNGARGCNATHMGNYTNGTNTTYAARCAYAGY GGNGTNGARTTYGARGAYAARMGNATHTCNATGGARGARTGGCCNGCNGTNAARAGYAAY ACNCCNACNGGNTTYGTNCCNGTNYTNACNACNGARGGNAARAARYTNGTNGARACNACN GCNATHYTNMGNTTYGTNGCNAARGAYTGYGGNGTNTAYGGNACNACNAGYGTNGARGCN GCNTTYGTNATHGARATGAAYAARGAYATHCARGAYAGYATHCARATHATHTAYTAYACN CCNGAYGARAAYGARAARAARCARAARMGNGCNYTNYTN------------GARAARAAR ATGATHGARGTNTGYAARTAYTTYAAYACNYTNYTNMGNAARAAYGARGCNAAYAARGTN GTNGGNATGAARATHAGYGTNGCNGAYATHTCNTTYATGGAYATGATHACNAGYATHGCN YTNCCNAAYAAYACNGTNYTNGARAARTTYTCNYTNYTNAARAAYYTNGAYATGGARGTN MGNTCNTCNGARAAYATGAARMGNTAYYTNAARMGNTGYCCNGTNCCNYTNMGNYTNATG AARGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHAARGTNYTNGARTTYGTNYTNTCNATHTTYGCNTTYGCN ACNACNACNAGYCCNGAYGARTCNACNACNTTYACNGTNAARAAYTGYAGYCARTGGACN AAYAAYACNYTNACNGGNCCNGTNTCNAARACNTAYTCNTAYAGYTAYCCNTAYGAYYTN GARAGYGTNTGYTTYGAYYTNCCNYTNTGYAARGGNAAYYTNCCNAAY---------GGN GARTTYTGYYTNYTNGARGGNTCNAARTCNTCNGCNCARTTYTAYGTNTTYGTNGGNGTN ATHGTNTTYYTNTAYTGYYTNGCNAGYYTNGTNYTNTAYGTNTTYTTYGAYGARYTNTAY MGNMGNAAYTCNMGNATHGTNYTNGCNGAYTTYGTNATHTCNTGYGTNYTNACNYTNTTY TGGATHATHTCNTCNTCNGCNTGGGCNGCNGGNYTNGAYGAYGTNAARYTNTAYACNGAY CCNTAYGGNGGNGGNATHTTY---CARTCNAARGCNGARTGYCARGAYAARGGNGCN--- TGYCAYACNGAYAARGARGGNAAYTTYGCNAGYYTNAAYGTNTCNATHATHTTYGGNTTY YTNAAYTTYGTNGTNTGGYTNGGNAAYYTNTGGTTYYTNTAYAARGARACNCCNTGGTTY AARGTNCARGCNAARCCNCCNACNCARCCNYTNTCNCARGCNAARYTNGARTGYGARTGG MGNYTNGCNTCNTCNYTNATHYTNGARAAYGARMGNATHCARCARGCNYTNAARGAYAGY CARGAYYTNCCNTCNTTYTTYAARTCNTTYATHGCNATHGCNGARAARTGYYTNAARGTN ACNGGNYTNCCNGARAARCARTGGACNGAYCAYTGYCARAAYGTNYTNAAYCARYTNCAR AAYATHGGNTGGAAYAARGTNATHGARATHGCNAARGAYTTYTCNAGYGTNGARYTNGGN TGYTAYGAYATHAGYCAYMGNMGNCAYAARYTNMGNGTNAAYTTYAAYAARGARAAYTCN GARGCNMGNCCNAGYTGYGTNACNGAYYTNCCNCARGARTTYGAYTTYCAYTGGTCNTCN ACNGCNCARYTNGAYGAYYTNYTNGTNCARTTYGARGGNGTNYTNGGNAAYTAYCARGAR TTYTGGAAYATGGCNGARGARATHGAYAARAAYACNTGGGTNYTNGARCCNGARCARCCN ACNTAYTCNTGYGCNTAYMGNMGNATHGCNYTNGGNCARAAYYTNTCNYTNCAYATHATH ATHAAYCCNYTNCARCCNTCNAGYYTNCCNGARTGYMGNYTNYTNGGNGCNGARAARGCN GTNTCNCCNYTNMGNGARAARYTNAAYGTNAAYYTNCAYYTNTGG--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GCNAARAARAAYAARGTNYTNCCNYTNTGGYTNMGNCARGGNYTNGARAAR ATGGARAARGARAARMGNAAR---------------------------ACNGAYYTNGCN AARACNAARGARAGYTCNGARTAYCAYCARGAYTCNCCNGTNTCN--------------- ---------------TCNCCNGTNGCNTCNCAYMGNTCNGARCARGARMGNAGY------ ---GARMGNCAYGARGCNGARGARTCNGAYGAYTCNGCNAGY------------TCNCCN MGNMGNMGNTCNATGAARTCNAGYCCNYTNCCNGAR------------------------ ---TCNCCNGARTCNTCNGARGAYGARGAYGARGARGARAARCARMGNCARYTNATGYTN AARATHAARACNTGGATGACNGARATHYTNYTNGGNGTNACNAAYCAYGARYTNAARACN YTNTGYAAYGARGTNTAYTTYGARATGAARMGNTCNGCN---AARGTNAARGCNACNCAR YTNMGNCARTCNGGNGGNYTNGAYGCNYTNMGNTAYGCNGGNYTN------GGNGGNGAY GARGARGCNTCNAGYAGYGARGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TAYGTNCARMGNAAYYTNGCNTTYGTNMGNTCNAAR AARGAYMGNGTNGAYTAYAARGAYGARGARGARYTNAARAARYTNGARCARTCNATGAAY AARCARCCNAAYCARGARATHYTNGAYCAYGARMGNAARMGNAARGTNGARYTNAARTGY ATGGARATGCARGARYTNATGGARGARCARGGNTAYACNAGYAARGARGTNACNGAYAAR GTNAAYATGTTYMGNAARATGYTNATGGCNAARGARGGNGTNTCNGAY---ACNCCNATH GARAARGAYGARCAYGGNMGNCCNATHGCNAARGARACNCAYCARYTNGCNGARGCNAAY CARATHAARAAYGAYAARYTNAARGARGCNTTYGGNYTNTCNGARTAYACNGAYGGNAGY GCNTTYGAYCCNGAYMGNAARGCNAARGARGARCARGCNAARGCNYTNGCNYTNGCNCAR AARAARTAYAGYATHGTNCAYAGYTCNGARGARGAYGAYCCNAAR---GARAGYTCNCCN GTNCCNAARAARAARAARAARAARTCNMGNCAYGAYGAYGGNTCNTCNCCNGARMGNAGY AARGARAARAARAARAARAGYMGNAARCAYAGYAARMGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNACNCARMGNYTNCAYGCNGCNGARAARGARMGN MGNCAYYTNYTNGCNGAYYTNACNGARYTNAARCARCARATHGGNGAYGARAAYACNTCN YTNCARAAYTCNACNGAYMGNCARTCNTCNAAYAARGGNACNAARTAYGTNTCNATGGAY AARTTYGARAARGTNTGYGTNGARYTNTCNAGYGCNYTNMGNMGNGARCARAARGCNCAR GTNYTNYTNCARGARCARAGYAAYCARYTNGCNGARYTNACNTCNMGNYTNGAYATHTGY GCNTCNGAYGGNGTNCAYAARGARAARAGYYTNGTNCAYATHCARGARGGNYTNACNGAR ATGCARGGNCAYYTNMGNCAYAARGAYCARAAYYTNMGNCARATHGGNAARCARGTNGCN CAYYTNGARTAYGARMGNAAYACNYTNCARAGYAAYYTNAARGAYGCNGARAAYGCNYTN MGNACNGCNGCNMGNGAYAARGARATHYTNGCNCARTAYATHMGNAAYGTNGGNAGYGCN YTNGARACNGCNAARAARCAYTTYYTNATHATHMGNGARCCNCCNCCNYTNTCNAAYGAY ATGTCNYTNTCNMGNYTNYTNYTNGAYTCNGAYYTNATHCCNATGGARATHGGNAARACN GGNCCNGARYTNATHTCNYTNCARAAYYTNGTNGGNGGNTTYGTNGAYGCNCARCAYCAR GCNGTNAAYAARATHMGNGCNYTNGARGARGARATHAARTCNCAYMGNAGYCAYATHGAR TCNYTNAARMGNGARYTNAGYAAYGCNGTNCARMGNGARTTYAAYCARCARYTNGARTCN GCNACNGAYGGNGCNTTYTCNGTNYTNACNGAYCARGARGAYGAYYTNGTNCARYTNAAR CCNGAYACNGAYAAYTCNTAYGARAGYYTNCCNACNCCNMGNAARYTNACNCCNCCNACN TCNACNAGYYTNGGNAAYCCNTCNATHCARCAYAARAARTCNGCNTTYCAYTCNGTNAAR TCNAGYAGYTCNYTNTAYACNACNTCNGCNGTNGTNGGNGCNGCNATHYTNAAYCARTTY ATGACNTGGTAYGTNAAYCCNAAYAAYYTNATHCCNGAYMGNCARGTNGAYTCNATHTTY ATHTTYTCNCARGAYGARGTNYTNGAYAARATHCCNTCNATGTTYYTNGTNTTYGGNGGN TTYAAYYTNGTNYTNCARGCNATHGGNTTYTGYYTNYTNAAR------------------ ------AAYCCNTTYYTNAAYGCNGAYATHGTNCAYGAYTAYCAYGAYTAYTAYAAYACN AARGCNYTNAAR---GAYGARGTNACNAARTAYTAYGTNGAYATHTCNACNGCNGAYAAR CAYGARACNYTNTCNGAYAAYCAYMGNGTNGCNGCNGTNATHCCNYTNAARTTYAAYTTY CCNTTYTAYGGNCAYCCNGTNAAYAAYGTNACNGTNGCNACNGGNGGNTTYATHTAYATG AGYCCNTTYYTNCAYCARTGGYTNACNGCNACNCARTAYATHGCNCCNYTNATGGCNAAY TTYGAYCCNTCNYTNAGYGAYAGYTCNAAYATHTTYTAYYTNAGYCARGARGAYATHTTY ACNGTNGARTGGMGNGAYGTNGTNYTNCARGAYCARAARGAYGTNGGNGGNTTYACNTTY CARACNTCNYTNCAYAGYAAYGGNACNATHAGYTTYYTNTAYAARGAYATHCCNYTNGAY GCNAAYAARATHTCNGCNGAYAAYCAYCCNGTNAARATHGGNYTNTCNGAYGCNTAYTAY AAYGAYACNTAYATHMGNCAYTTYGGNATHMGNMGNMGNACNATHTAYGARTAYCAYCAR GTNGTNYTNCARAARAGYYTNGCNAARACNGGNGCNGTNATHTTYATHGTNCCNGTNCCN ACNTGYAAYACNYTNAAYGAYTGYGARTCNTGYACNAGYCAYATHAAYGTNGAYTTYGAY TGYATGTGGTGYAAYACNATHGGNMGNTGYTCNGAYGGNYTNGAYTGGTAYMGNCARCAY TGGGAYMGNTAYTCNTGYACNAGYYTNAGYACNAAYCARACNCARGAYTGYATHGGNYTN CCNGCNCCNACNMGNCCNATHYTNGAYCCNCARAGYCARACN------------AARAAR TGYAARGGNGGNAARTGY---GAYGAYGGNAARGAYGTNCCNGCNGCNGTNATHGTNGTN GTNYTNYTNYTNGTNYTNACNYTNATHGGNGGNGTNATHGGNTGGGTNTAYTAYGCNTAY ACNCAYCCNACNTCNAARTCNGGNATGTGGYTNATHCARCAYMGNCCNAGYCARATHAAR GCNAARATHCARTTYTGGAARAGYAGYAGYAGYAGYTCNGCNAARTAYMGNGCNGAYACN GAYGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNGARYTNGAYGCNCCNGTNGGN CAYCAYGAYGGNTTYTTYAAYCAYAARMGNTAYTTYTTYTGYCARAARGAYCAYGGNGTN TTYGTNCCNYTNCAYGAYATGGTNTGYAARGTNGGNGGNAARGCNGARGAYTGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYATHMGNAARCARACNGCNGARGTNTCNTCNTGGYTN TCNTAYGTNYTNAARCAYAARCCNATHCCNGAYTTYGARATGACNGCNCARACNYTNCAR YTNYTNCAYMGNYTNTCNGTNGTNAGYCARTTYAAYGARMGNAAYGTNMGNYTNTGYGTN GAYGAYTTYAARAARAARTCNGARGARTAYAGYACNGAYGTNCARMGNATHGGNTGYATH YTNGAYAARYTNACNTTYGGNCARAAYAGYYTNTCNMGNTCNGGNTAYTCNTGYGTNCAR GCNYTNTCNMGNGCNGGNGCNYTNYTNGAYGTNAARGAYGCNTCNGAYACNTGYTAYATG YTNTCNATHMGNGARYTNAARTCNAGYGTNGAYGARYTNACNGARAARYTNGARGCNGGN AAYGARGAYYTNCARAARYTNTCNAARAARACNCARACNGTNYTNYTNAARCAYAGYTCN YTNGARAARGTNYTNGARGTNYTNGARAARAARTCNACNCARAARACNGGNMGNATHGCN GARMGNAARAARGARACNTCNATHYTNMGNAARGCNACNGCNGARAAYGARYTNACNATG GARAARYTNAARGGNMGNYTNGTNAARTCNGGNGTNAGYCARTCNGAYTTYCAYGGNAAR YTNGTNAARAARAARGARAARYTNGAYGCNYTNGARAAYGARYTNGAYCCNYTNAARYTN GARYTNCARTCNTAYATHAGYYTNCCNCCNGAYACNGTNGAYGCNAARGTNAARATHGAR CARYTNAARMGNGARYTNAGYGARYTNCARACNAARATGTCNGARTGYGTNGAYGTN--- ------------------------------------------------------------ ---------------------------------------TGYCCNAAYCCNGGNAGYCAR GAYAGYYTNGAYATHAAYCARTAYYTNGGNAARTGGTAYGARTAYGARMGNTTYAGYGCN TGGTTYGARYTNGGNGTNGTNTGYGGNAGYGCNCARTAYGGNYTNAAYCARGAYGGNTCN YTNAGYGTNACNAAYGGNGGNTAYMGNAAYATH---------------YTNGGNTTYAAR GTNCCNACNTCNATHACNGGNMGNGCNATHACNCCNGAYCCNGCNMGNCCNTCNGARYTN MGNGTNTCNTTYTCNMGNTTYGAYMGNTCNACNGGN---GGNCCNAAYTAYTTYGTNGTN GARACNGAYTAYACNGGNTAYACNGTNGTNTTYTCNTGYACNGAYYTNCCN---TTYGGN TAYAGYAGYCARTTYGCNTGGATHYTNACNMGNGAYMGNGGNGTNGCNCCNTCNAAYYTN GCNGCNATHAARTCNMGNYTNACNTCNCAYGGNGTNAAYGTNGGNTAYTTYAAYTCNGTN GAYCARTCNGAYTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNATHMGNMGNGTNGTNGGNGGNCARCCN GTNTCNATGGGNACNTGGCCNTGGYTNGTNTCNYTNCAYTTYCARGARGAYCAYCCNTAY YTNMGNYTNCARGGNYTNGAYCAYYTNTGYGCNGGNGCNYTNATHGAYCCNTAYTGGGTN YTNACNGCNGCNCAYTGYGTNCAY---CCNYTNYTNTAYMGNGGNYTNGAYAAYCCNTCN AAYTGGATGGCNGTNYTNGGNGAYTAYCAYMGNMGNGTNGARGARGCNACNGARCARATH YTNGCNATHGARCARATHTAYGTNACNCCNAARTTYGCNTGGAAYCCNGCNTTYACNGGN GAYATHGCNYTNYTNAARYTNGCNCARCCNGCNACNCCNTCNTCNCARGTNMGNCCNATH CCNATHGAYGAYGGNATGTAYATHCCNGAYGGNGCNCARTGYGAYGTNGCNGGNTGGGGN CARCAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TGYAGYMGNYTNAARGARATHMGNGTNYTNATHCARGGNYTNGAY GCNGCNGGNAARACNACNYTNYTNTAYMGNYTNAARYTNGGNGARATHGTNACNACNATH CCNACNATHGGNTTYAAYGTNGARACNATH---GARAGYACNGGNYTNGCNGTNACNGCN TGGGAYYTNGGNGGNMGNGAYAARATHMGNCCNYTNTAYMGNCAYTAYTAYCCNGGNACN GAYGGNTTYATHTAYATHYTNGAYAGYTCNGAYGTNGAYMGNATGGARGAYGCNTTYGAR GARYTNAAYAGYATGATHYTNAARGARGAYTCNACNMGNGAYACNGTNGTNATGGTNYTN GCNAAYAARCARGAYYTNAARGAYGCNYTNTCNCCNGCNGARATHGARGAYMGNYTNAAR GGNAGYTCNCCNYTNAAYYTNAAYCAYTCNYTNTTYGTNATGCCNTGYTCNGTNACNYTN GARGAYGAYCARCCNATGTGGCAYACNTTYAAYCAYTTYGTNAARATGATHAARATGAAR CARGARGAR---------------------ATHACNCARTCNGARGCNGARGAYAARGAR ACNACNCAYGARGCNTCNGCNTTYCAYAARYTNAARACNTCNATHAARGAYCCNTTYAGY YTNYTNAARTCNYTNYTNTTYTAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AGYGGNYTNATH GGNMGNAGYTTYACNATGATHTTYGCNAGYGCNGGNTAYGAYGTNATGATHTTYGAYYTN GAYCCNGARCARACNTCNGCNGCNAARGCNGAYATHCARATHCARYTNTCNAAYYTNGAR AGYTCNGGNYTNYTNMGNGGNAARYTNTCNAARGARGARCARTTYAGYAARATHTCNACN ACNGARAGYYTNGAYGARTGYGTNAARCARGCNTTYTTYATHCARGARTGYGTNCCNGAR MGNYTNGARATHAARMGNTCNGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYGTNGTNTTYTCNTTYGAYACNACNGGNTCNATGTCNCARGCNYTN GAYGARGTNAARGCNMGNGTNATGGAYATHGTNCARAARYTNCARGCNGAYATHCCNGGN GTNMGNATHGGNATHATHGCNCAYGGNGAYTAYTGYGAYGCNGARCAYTTYTAYGAYATH AARAGYYTNGAYYTNTCNGAYAAYGTNGCNGAYGTNGTNACNTTYATHAAYGAYACNGAY GGNACNGGNGGNGGNGAYTTYCCNGARTGYTAYGARYTNGCNYTNMGNMGNGCNAARAAY ATGAGYTGGMGNCCNGTNGGNYTNMGNATHYTNGTNGTNATHGGNGAYTCNTAYCCNCAY GARGCNGAYTAYCAYATGAAYGTNGAYAAYATHGAYTGGMGNCARGARYTNAAYGAYYTN GCNGCNATGAAYGTNCAYATHTAYGGNGTNCARGTNCARCARGAYGARGARAGYTCNAAR TTYTTYAGYGAYYTNGCNGGNMGNACNGARGGNCARCAYYTNMGNYTNGARAAYATGGGN MGNGTNTGYGARGTNATHATGGGNATHTGYTAYMGNGARCARGGNCCNGTNATGTTYAAR AAYTTYGARGCNGARATHMGNCAYAARGARGCNAAYCARYTNGCNCCNGAYYTNGARTGY GTNTTYGGNACNYTNMGNCAYGARGTN--------------------------------- ------------------------------------------GAYGGNGAYTCNAARMGN ATHYTNCCNTGYGARCAYGARYTNCAYAARGAYTGYATHGAYCARTGGYTNAARACNAAY GCNACNTGYCCNATHTGYMGNAARGAYATHMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNACNGGNGARTGYGAYCARTAYATHCCN YTNAGYACNYTNCARGGNATHATHCCNCCNAAYYTNTTYTCNAARATHGTNAGYMGNYTN CARGARGARGARGTNYTNCARGCNCARATHCCNGAYYTNGTNACNTGYCCNTTYTGYCCN TTYGCNACNATHATGCCNGAYCCNGAYGAYAARGTNYTNAARTGYYTNAAYCCNGARTGY YTNAARGARTCNTGYMGNYTNTGYMGNGARGAYAGYCAYATHCCNYTNAARTGYAAYGAR GTNGARAGYMGNGCNGGNACNMGNATGMGNACNTAYATHGARAAYMGNGTNGCNGARGCN GTNATG------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNACNTGGTGYMGNCAYGTNACNYTNACNMGNGGNYTNTGYCAR CARGAYGARTCNGGNGARGARGTNGCNGGNAAR---------CCNAARMGNMGNGTNGTN GAYGTNGAYACNAGYATHMGNTAYGTNCAYAGYCARGCNTTYTCNGARAGYTAYAGYGAY AARCCNGTNTGGTTYTAYTAYMGNMGNAAYTTYAARGGNMGNTTYYTNCCNCCNACNMGN AARACNTGYATHMGNMGNGGNGTNYTNTCNACNCCNAGYCCNTGYCCNATHTGYMGNGAY GARTAYYTNGTNYTNGAYGCNAARAAYACNAARYTNYTNTCNCARTTYATHAAYCCNTAY ACNGGNGAYATHYTNGAYTCNATGAARACNGGNYTNTGYCARGARCARCAYMGNAARYTN TCNYTNGARGTNATGMGNGCNMGNGAYYTNGGNTTYATHGARATGGARGTNCCNGAYMGN ACNTAYGAYTAYGAYGAYTAYAARACN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATHCAY------------------ ------------------------ACNTTYCCNTGYATHCCNGAYTAYAAYMGNGAYAAR ------------------------------------------------GTNYTNATHGTN TTYCCNGGNGARAAYTCNGTNAGYYTNGARGAYYTNAARTTYGCNGARTGYGARACNAAY TCNACNATGGCNGGN---------------------AGYATHTCNTCNACNCCNCCNATH CARGAYAGYATHAAYAAYGAYACNACNTGYGTNAAYAARCCNTAYAGYAGYCARAAYAAR AAYATHAAYTCNTAYAAYAAYATGGARAAYGCNGTNYTNTGYGARAAYTCNCCNTCNCCN GGNTTYGCNAARTCNGAYGTNGTNAGYGARAARGAYTCNYTNYTNAARCCNAAYGAYCCN AAYAARACNCARGAYYTNAARMGNAARMGNGAYYTNAGYAAYGARGAYGARAARGAYACN ACNTCNCCNAARAARGTNCARAARACNGGNYTNMGNMGNTGYCCNTTYGARMGNGTNGTN TTYATHGAYTGYACNTGGAAYCARACNAARCARATHGTNAAYGAYGARMGNYTNAARGGN YTNAARMGNGTNGARYTNAARTCNCARTTYACNCAYTTYTGGMGNACNCARGARGGNATG CCNAARACNTAYYTNTCNACNATHGARGCNATHTAYTTYTTYTTYAARGAYTTYCAYTCN ATHTTYGTNGAYYTNGTNTAYAAYCAYGARTAYGAYAAYYTNYTNATGTTYTTYTGYTTY ATGTAYCAYAARATHAARCARAGY------ATHACNTCNATHYTNTAYMGNGAYGTNMGN TAYTCNMGNTGYYTNAARGARCAYGCNGAYYTNGCNTCNAARGTNGGNATHCCNCARCAY TAYGGNATHTTYTAYGCNATGGGNTTYGCNYTNATHATGGARGGNGTNATGAGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TAYAARAARTTYCAYCAYTCNTTYGCNGTNYTNATHGARGGNATG GCNTCNAARYTNAARTCNAAYGCNCCNAARGCNYTNTCNTCNAAY------GCNATHYTN AARATHYTNCCNTCNGAYTCNAARTGGTTYAARCAYMGNGAYGTNAARGCNATHTCNAAR YTNACNAARACNACNYTNGCNTAYACNTCNYTNTAYYTNAARAAYGTNCARGAYTGYYTN AARACNGAYAGYAARYTNTGGTTYGGNATHCARAARATHCAYYTNGAYYTNCARATHCCN AARGTNAARACNGAYYTNGAYAARTTYYTNACNGARGAR------AAYGTNGCNACNGGN TCNACNGGNGCNGGNGGNGTNAAYCCNGGNGTN--------------------------- ------------------------------CARYTNTCNACNTTYAARAGYAAYYTNAGY YTNGAYAARGTNTAYCCNCAYTCNAAYYTNGAYTAYYTNMGNGGNAAR---------CAR GARATGAARAGYGAYGCNGARACNTTYTCNGGNTAYATHCCNGTNGARCARYTNGARATH AAYTAYAGYMGNAGYGGNGGNCCNGGNGGNCARAAYGTNAAYAARGTNAAYAGYAARGTN GARATHMGNTTYCAYATHGAYTCNGCNTCNTGGATHCCNGGNTGGATHAARCCNMGNYTN CARGARCARGARCARAAYMGNATHACNAARGAYGGNTTYYTNATHATHAARTCNGAYATG ACNMGNAARCARATGYTNAAYCARGCNGAYTGYYTNAAYAARYTNMGNAAYGTNATHTAY CARGCNTCNATHYTNCCNAARGARCCNACNGARGARGARYTNCARAARAARGARMGNAAR ATHATGAARGCNAARGCNCARGTNYTNMGNGARAARMGNMGNMGNTCNCARGARAAYMGN TTYAARTCN------------TCNTCNCARGCNATHACNCARYTNAARTAYAAYCCNTAY TAYAARTCNTCNYTNGCNTCNGCNTCNGARGAYGGNGTNGTNGCNTTYTGGGAYACNAAY ACNMGNAGYMGNGTNCAYGTNTTYAAYACNAGYCCNCARGCNCCNGCNACNGAYYTNGCN TTYTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GCNAARGCNAGYGAYGAYYTNYTNAGYYTN GCNTCNAAYCCNTTYGCNAGYAAYGTNCARGAYGTNATGGCNACNGCNTAYCARGCNCCN GCNAAYAGYGCNCCNAAYAAYCCNTTYGGNACNCCNGCNTTYCARTCNAAYGGNATHGGN GCNGCN---AAYTCNAAYAAYTTYGAYGCNGAYTTYGCNAAYGCNTTYAAYAAYACNGGN ACNAAYTCNCARGGNGCNCCNCCNGGN--------------------------------- TTYGAYGCNTTYGGNGAYGTNYTNGCNCCNATGAAYAARTCNCCNTCNCAYCARGCNCAR AAYAGYCARGGNGCNAARCCNYTNGGNGGNGAYYTNGAYTCNTCNYTNGCNTCNYTNGCN TCNAAYYTNAAYGTNAGYGGNGGNACNGGNCARYTNAARAARGAYCAYCARTGGCAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY AGYMGNAARMGNYTNNNNCCNTGGYTNAARCAYACNGAYGCNGGNGAYNNNGGNYTNNNN TGGGTNNNNAARNNNGARNNNATHTTYMGNATHCCNTGGNNNNNNNNNNNNAGYNNNNNN TGGNNNNNNNNNCAYNNNCARGTNYTNAARGARTGGGCNNNNNNNACNNNNAARTAYNNN NNNGGNGAYNNNGARGAYTAYNNNNNNTGGAARNNNMGNATNNNNNNNGCNYTNACNNNN YTNNNNGAYTTYNNNGANNNNNNNGANYTNCAYNNNNNNNNNGAYNNNAAYCCNTAYAAR GTNTAYMGNTTYAARATGGCNGGNMGNCCNAARTCNGGNATHACNGCNGAYACNGAYGTN AAYYTNGAYTTYYTNACNAARGARGARAARGAYGCNYTNYTNTCNAARAARATGGAYATG ATHMGNCARMGNAAYAARATGATHAGYGARMGNCAYGARYTNATHGARGCNGAYMGNMGN AARGCNGARGARTCNGGNAAYGCNGTNAARGCNATGGAYAGYAARACNYTNCCNGCNGAR GGNGCNCCN------AARTCNMGNGGNMGNGGNMGNGGNCARNNNNNNGGNCARGGN--- CAYMGNGAYGGNAAYMGNAAYAGYMGNGAYMGNCCNAARTCNCAYGGNGAYACNTCNTCN TAYGARCCNATHGTNGAYGTNAGYGAYTTYACNAAYAAYMGNAGYAAYAAYMGNGGNGGN AAYAARGGNGGNCARCARCARCARCARCARCAYAAYCAYCAYCCNCAYCARGAYMGNGAY GGNTCNACNTCNACNCCNAARAAYMGNMGNAARCCNCAYCARAARGAYGARGCNGGNTTY MGNCARCAYTCNTCNGTNTCNCCNCCNGCNATGGCNTTYGAYTAYGARCCNATHGTNGAY YTNAAYGAYYTNGAYCAYMGNTTYGGN---------------ACNMGNGGNACNTCNTCN TCNTCNCCNGCNACNCARACNAARCCNTCNATHCARAARGAYGGNAAYAAYAAYACNMGN GGNTAYAGYGCNGGNGGNCAYTCNMGNTCNAAYMGNMGN---------CCNTAYAGYGGN MGNYTNAAR---GAYAAYAAYCCNCCNCCNGAYCCNTCNTTYAAYCCNYTNTCNGAYMGN MGNMGN------------GARGAYMGNAARGARGGNCCNGARMGNTCNGAYMGNCCNGAY CAYAARMGNCAYCCNMGNAAYTAYGGNGGNGGNGCNGAYYTNGCNAARGTNAARGAYAAY ATGAARACNATGMGNGARMGNGARAARGARMGNCCNGTNTCNTCNMGNAAYYTNGARATG GTNATGACNGGNMGNGARMGNAARAAYCAYGARCARTGGAARCARGAYMGNGARMGNTAY GAYAAYGARMGNATHCARMGNCARATGGGNGAYGCNGGNGGNTGGAARMGNGARTGGGAY CAYGAYAARATHGTNYTNGAYTAYGAYGAYCAR------CAYCAYTCNAARATGGARCCN GCNAARMGNCCN------------------------------------------------ ------------------------------GCNGGNMGNATHGGNAGYGGNMGNTTYGAY MGNGGNGAYAGYMGNGAR---------------------------------------GAY MGNCCNAARGCNGTNGTNMGNGAYGGNAARGCNCARCARCAYCAR---YTNCARCARCAR CARCARCARCAYGCNGAYTCNAARGCNGGNMGNGGNMGNGGNMGNGGNMGNGGNMGNGGN AARGGNGTNGGNCARGGNCARGGNCCNGGNACNGGNGGN---GARAARTCNCCNMGNCCN MGNACNTGGTCNGGNGGNGAYGAYMGNTTYGTNGARTGYCARAARGARATGYTNGTNGTN AARTTYGAYAAYACNGTNGGNGAYAAYTCNGTNGARGTNGARTAYGAYGAYGGNGCNCCN YTNTCNCCNACNCCNTCNTCNMGNTCNTCNGGNTCNACNCCNGGNMGNGGNCCNACNGGN MGNACNCARAAYCARGGNGGNGGN---GGNAGYAGYGGNTCNTCNAGYCAYAAYCARCAY TCNCARCARCARCARGARCARCARAARCARTTYAAYAAYYTNCCNMGNGTNCAYCAYCAY GAYCARTTYGTNGAYGCNGARTGGGAYAGYMGNCAYTCNTAYGAYGGNTCNATHCCNCCN ------AAYTCNAARGTNMGNACNYTNTCNTCNCAYTCNCAYAGYCARGGNGAYAGYGAR GARTGGGARGAYTGYACNGARTCNTCNGGNGCNYTNGARGAYGAYGGNYTNYTNCARYTN CAYCAYCARAAY------YTNCAYYTNGARTGYCARYTNAAYCCNGARGCNCCNGARTTY YTNCCNACNTCNCCNGAYTTYYTNAARACNCCNCCNGGNCAYGTNAARGTNYTNAAYTGG GCNGGNAGY---AARAGYCCNACNTCNCCNCARTCNAAYYTNAGYCAR------------ ------------------------------CCNGARYTNTCNCCNMGNCARCARCARGGN TCNGARTCNAAYCARTCNACNGTNTCNTCNCCNGGNTCNTCNGCNTCNACNMGNGCNAAR AAYMGNCARGARGTNATHGAYGTNATGCCNGARCCNGAYGARCCNTTYCCNCCNCCNTTY YTNYTNAAYGCN---GCNGARYTNACN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARYTNCARGCNTTYGGNAGYAAYGCNACN TTYAAYAARATGGAYGCNATHMGNATHCARCARGARCARYTNGCNAARCARCAYTTYGAR YTNGAYYTNYTNCCNMGNTCNGCNTCNAGYMGNYTNAAYGCNGARGARTCNMGNAARGAR AAYAGYGARAARATGGAYAARYTNATHGARCARTGYGAYYTNYTNATHATGGCNAARATH AAYGTNACNATHAARGTNATHTGYGCNATHAAYAAYCARAARCCNATHGTNACNCCNGAY TAYYTNGAYCAYTTYCAYCARTTYYTNGTNGGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CCNGAYCCNATHCCNGGNCARCCNTAY GCNGGNGCNCCNGCNCARMGNGTNGGNAGYGCNCCNYTNMGNAARATGGCN---AAYCAR GGNACNGCNAGYMGNGCNAAYGCNGCNAAYAAYMGNTCNTCNYTNGARGCNGGNGARACN ---------ACNGAYTGYCCNAGYCCNTTYATGMGNCCNCAYTCNMGNTTYGARACNGGN YTNGARCARGTNCARTCNCARCAYCAYCCNAAYTTYYTNCCNCCNATGCCNMGNCCNTCN CARGCNTCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GTNATHCAR AARGCNYTNGARTCNATHCCNTCNGAYATGCARGTNGARATHGTNAARGARYTNGAYGGN CAYGTNYTNAARTGYGTNAARGAYCARAAYGGNAAYCAYGTNGTNCARAARTGYATHGAR TGYGTNGAYCCNGARTAYYTNCARTTYATHATHGAYGCNTTYAARGGNCARGTNTAYNNN YTNTCNACNCAYCCNTAYGGNTGYMGNGTNATHCARMGNATHYTNGARTAYTGYACNGTN GAR--------------------------------------------------------- ---------------------------------------------------ATGAGYACN TCNGTNAGYACNATGMGNGCNGGNGCNAAYAARYTNCCNGGNCCNAAYGAYAARACNGCN AARAAYGAYATGAGYACNTCN---CARGCNACNACNACNGCNAARACNGAYGGNCAYTCN AARAARATGCARCCNACNCARGARCARYTNMGNYTNGCNCARATGATGAGYATHAAYCAR ATGGAYGCNGAYCCNAAYACNGTNAARCARYTNATGGAYATGACNGGNAARAGYGARGAY GAYGTNGTNATHGCNYTNCAYGAYGCNGGNAAYGAYGCNGAYMGNGCNGTNATGACNYTN YTNGARGGNGGNGARGARCARGAYGARTGGMGNGARTGYGGN------AARMGNAARAAR MGNAGYACNCARAARGAYAGYACNAAYAAY------GARGAYCAYTCNGAYAAYMGNAAY MGNGARMGNGGN---------------------------GAYAAYCARGAYYTNCCNCCN MGNMGNGGNMGNMGNAAYGGNGTNCCNCCNCCNMGNYTNGCNMGNGGNMGNGGNMGNGAY MGNGGNAAYTTYGGNGAYMGNGAYAARGARMGNAAYAAYACNTCNTCNGARGAYTGGGAY AAYGAYAARGARGAY------------------AARGGNTCNMGNGGNGAYAARGGNGAY MGNGGNMGNTTYMGNGGNMGNGGNGGNTTYAGYGGNMGNMGNCCNGCNGGNGTNATGAAY AGYAGYMGNGGNGGNMGNTTY------AGYAGYGAYMGNGARAAYMGNGGNTTYACNMGN CCNMGNMGNTTYGARAAR---------------CCNYTNAAYGGNCCNGARCCNGARATH GAYGTNTGGACNAAYGARACNGCNGARACNAAR---TCNAAYAARGAYACNGAYTGGAAY AGYTGGCAYGAYTTYGGNGTNAAYGARGARGAYCARTGGACNGGNACNYTNGARGARACN AARGTNTTYACNCCNTCNCAYGTNAARACNCCNGARACNGAYTCNGTNAAYAAYGARCCN CCNAGYTCNMGNGGNCARMGNYTNGAYGTNGAYAGYYTNTTYGARAGYGCNAARTTYACN AARGCNCCNGAYTAYAGYAARCCNAGYGGNGAYTCNTAYATHAAYCARTTYAAYCARGCN GCNACNGARTCNATHAARAAYACNATHGGNATHGGNAAYACNACNMGNCCNCARATHCCN YTNTCN---------------CCNCCNGAYACNTCNGGNTCNYTNGGNYTNTCNAAYYTN GGNCARAARACNGCNCARCCNCAYGGNAGYTCNGTNYTNCCNTCNYTN------CARCAR TCNGCNCARCARAAYTCNYTNCCNCAYGCNATGGCNCARYTNTCNCARATHTCNCARCCN GCNTCNCARTCNACNAGYATGTCNCARATGGGNATHGGNTCNCCNCCNAGYCCNGCNTCN TCNAAYCARGCNCCNCAR------------------------------------------ ---------------CARTCNMGNATHCCNGCNGTNGTNCARCARCARCARCARCARYTN CCNCARACNAGYATH------------------AAYAAYATGCCNCARMGNCCNAARACN CARMGNTCNAARYTNCCNCCNCCNTCNAARATHCCNTCNACNGCNGTNGARATGCCNGGN CAYATHCCNMGNAAYCCNCARYTNGAYGTNCARTTYGGNYTNGAYTTYGGNTCNGARACN TCNGTNCARTTYGGNTTYGGNGGNAAYGGNGAYAAYACNGCNGTNACNAGYTCNTAYTCN ACNACNACNAAYGGN---ACNACNGCNATGTCNAAYCAYYTNAAYCARGCNCAYATGACN CARTCNGCNGGNGAYGGNAAYCCNGTNTCNCARATHYTNCCNTCNCCNCCNTCNGGNTCN GCNAAYGTNCCNACNGGNATGGARCCNCARGGNACNAAYMGN---CARGGNGTNTTYCAY AAYTCNATGTAYCCNTCNTCNCARCARAARAAYGARAGYCARTCNYTNGARYTNGAYCAR AAYAARGTNAAYGAYTCNATHCCNTTYYTNTCNTCNCARYTNGARMGNAARTCNAGYCCN ATGGCNTCN---CARMGNACNGGNCARCCNAAYCARAAYYTNGCNTCNGGNCCNATGACN TCNAGYAARAGYGAYTCNACNAGYGCNGTNGCNAAYAAYAGYTAYTCNGTNGCNAAYGGN TAY---TCNACNTCNTAYCARAGYCAYCCNAARGGNTCNTCNATHTCN------CAYACN GCNAGYTCNCARCCNTCNCARACNTCNTCNTTYCAYGGNCARTAYCCNGTNAAYCARTCN TCNTTYCCNTCNACNGGNCARACNCARTTYCCNACNCCNCCNAAYGCNACNGCNTTY--- CCNTCNGCNCARCCNTCNCARTAYAGYACNTCNAAYTCN------TCNCARAAYCARTAY TCNTCNGGNCARAAYCARTAYTCNGTNGGNACNTCNACNYTNAAYCAY------CARAAY AAYCARTTYCCNGCNTCNGGNCARAAYAGYTAYGCNAGYGGNTCNTCNTCNCARTTYTCN GGNTAYCARAAYAGYAGYTCNTTYCCNCCNCAYCCNCARTCNCARACNAAYTTYCCNTCN AGYCARAAYGGNGGNGCNGGNGCNGTNYTNTAYCCNACNTCNACNCARTCNAGYGTNCCN TCNTAYACNACNCARTCNAGYTCNTAYCARTCNCCNTCNGCNGGNTCNTAYCAY---TCN TCNMGNGAYGGNTCNGCNGCNGCNGTNAGYACNCARTCNAGYAGYGGNATGGCNTTYCCN AGYCARCCNCARAGYTCNAAYYTNAARCCNGCNACNACNCARAGYAGYTCNAGYTTYAAY TCNCARAGYTAY---ACNACNCCNACNCCNYTNCARCCNTCNTCNYTNGCNAAYAARYTN GGNGARAGYYTNTCNAARATHTCNATGAARGAY---AAYTCNGTNYTNGAYAGYCAYCAR TCNTCNCARTAYGARCAYACNCCNTCNCCNGCNAGYGTNCCNACNAGYGTNAGYYTNCCN TCNGCNTCNAGYTCNGCNTCNYTNTCNACNGGNTCNAGYGCNATHTCNTCNACNTCNACN GTNACNTCNGCNTCNCCNGCNTCNMGNGTNGCNTCNATGCCNTCNACNTCNGGNAARGCN CCNCCNAAYYTNCCNCCNGGNGTNCCNYTNATGGGNCARTAYATHATGGGNCARAGYACN ATHCCNCCNTTYTAYAGYGTNCARCCNCCNYTNTAYGGNTAYGARGAYATGCARYTNYTN CARCARMGNATGCCNATGCARACNGGNAGYTTYTAYGAYGTNAGYGCNTTYCCNGCNGCN CCNGCNGGNTCNACNYTNCCNACNGGNMGNGAYGCNCARCCNCCNATHCCNAAYGTNCCN TTYTCNGGNACNTCNGAYACNAARYTNACNMGNGTNGAYGCNCARAGYCCNAAYGCNTCN AGYCARCCNCARAGYGCNCAYTCNGCNGCNCARCAYCCNYTNTTYAAYTTYCAYTAYGGN TAYTAYTAYCCNTCNATGTTYCCNGGNGCNGCNGGNYTNCARTAYCCNACNACNGTNTAY CCNATHCCNCCNGTNACNAAYGCNGCNGCNCAYCARGGNACNACNGCNACNACNCARTTY CARAARACNTAYCCNTCNCAYGTNTAYACNACNAARGGN--------------------- ------------------------------------------------------------ ---------------TCNGGNACNAGYGARATHACNCCNAAYGCNTAYAGYAARTCNCAY GGNCARGCNGGNTTYGAYAARCARGGNTAYCAYGGNGGNACNCCNCCNCCNTTYAAYYTN CCNYTNGCNTCNGCNACNCARACNGGNCCNATGGGNGCNCCNACNACNCCNTAYGGNGCN CCNTTYYTNCCNGTNATGGCNGCNCAYCARCCNCAYTCNCARATGATGCAYCAYCCNATH CARCARGAYAAYACNACNACNAAYTCNMGNGGNYTNAAYCCNGCNGGNGGNCARGGNAAR TCNGGNGCNGCNAARTCNTTYGGNGGN---CCNCCNTAYTGGAAYAAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AAYGARAAYTCNYTNGTNATHTTYMGNYTNGTNATHTAYGGNYTNYTNATHACN YTNAGYTTYTTYATHTTYGTNGGNAARGTN------------------------GGNAAR TGYCCNYTNTAYTTYGARATHAARGGNAARYTNTCNTAYATHCAYTAYAAYTCNAGYTGY GARTAYCCNATHGCNGTNTCNATHGCNTTYCARYTNGTNTTYYTNYTNYTNMGNATGATH TCNYTNATHYTNGCNACNATHGGNAARYTNTCNAARGARGTNTTYYTNTTYTCNAARCCN TTYGARTTY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGAYTCNAAR TTYAARMGNMGNATHCARCARMGNYTNTAYCAYGCNTGYGCNAGYGAYTGYGAYAGYGAY AGYGAYGTNGAYGGNYTNAGYACNTCNTCNYTNCCNYTNACNGARACNTGYATGGARTAY TTYCARGAYAGYTTYCCNGGNTCNGARGGNYTNGGNMGNYTNGAYATGCCNATGGCNGCN ACNATHACNAARMGNAAYCARGTNTCNCCNTGYTCNGTNGTNYTNTCNATGATGTAYGCN AARMGNYTNMGNCARMGNAAYCARCARTAYYTNCAYTCNATGTCNTCNACNGAYGTNTTY TTYATHTCNATGATGATGGCNAGYAARTAYYTNTAYGAYGARGGNGTNGAYGARGARGTN TAYAAYGAYGARTGGGCNGCNAGYGTNGGNCAYGARACNGARGAYGTNAAYCARATGGAR ATGGAYTTYYTNAARGARATGGAYTGGCAYYTNTTYGCNAARCAYGARGAYTTYGAYACN GCNYTNACNGCNGTNGARMGNMGNYTNGCNYTNMGNGARGGNGTNMGNMGNGGNTGGTTY ACNTAYACNGARATGTCNGTNYTNYTNGAYTGGGARCCNATGYTNAAYYTNTGGAAYCAR GTNAGYGTNGAYTGYACNAARATGGTNTCNYTNYTNTCNGCNGTNTAYGTNACNAGYYTN GTNAGYATGATGGGNTCNGCNGCNATHGCNYTNCARYTNTCNGGNCCNYTNGCNTCNGCN ACNATHGCN---------------------------------------------YTN--- ---AARTGYTGYCCNAARGTNTGGAAYTAYGGNTGYMGNCAYGTNAAYTCNMGNYTNCCN TGYTTYYTNAAYTTYAAYAAYAAYGCNMGNGARTGGTGYTGYCCNATHTTYCCNCARCCN ACNATH------GCNMGNTGYYTNTGYGAYAARTGYGCNATHGCNACNAAYTCNTGYATH CAYYTNGGNMGNTGYCAYAARMGNTAYACNMGNMGNAGYTTYGTNGCNGTNTGY---TAY MGNTTY---GGNTGGAARTAYYTNMGNTTY---AGYAARTGGGTNCCNTCNAGYTGYTAY TGYMGNATHAARACNMGNYTNTTYTAYGTNYTNYTNGTNTTYTCNACNATHYTNAAYTAY GCNTTYTTYACNYTNAAYACNTAYTAYAARACNTTYGGNYTNYTNTAYATHCCNGAYGAY CAYTTYYTNACNYTNATHGTNATGATHAARTGYTTYGCNATGCCNGTNTGYACNTGGATH GCNGGNTTYTGYGTNGAYAARTAYGGNGTNAARCCNACNATHGTNACNGTNTCNTGYATH TTYTGYATHYTNGCNGCNTTYTTYGAYYTNACNTTYAAYMGNTGGYTNTAYYTNTTYACN GTNYTNTAYGGNTGYTCNYTNTTYAGYYTNTTYTGYYTNACNTCNGCNTGYTGYGTNAAR YTNTTYGGNCARAGYCAYTTYTCNACNATHTTYGGNYTNATHYTNACNYTNAGYAAYATH GTNGCNYTNTCNATHCCNCCNATHACNCARTGGATHATHTCNCAYTAYGGNTGGATGTTY YTNTTYAGYTCNGTNGGNGTNYTNGCNYTNTGYCARGTNTTYGTNYTNATGGTNTGYGTN CCNTGYTTYYTNATHCCNATHATHYTNTGGGTNTTYCAYAARTTYATHCARCCNTGGYTN TCNAARATHTGGGGNAAYTCNGARAAYTAYGTNACNAGYAAYYTNACNTGYCCNATGCCN CARAARAARAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CAYCCNGAYGGNAARGAYATGCARATHAAYYTNACNGGNTTYYTNAAY GGNAARAAYGCNMGNGTNTTYGTNGCNGARYTNTGGACNCAYYTNTGYAGYGCNCARGAR AAYATHACNGGNATHCCNAAYGARTTYYTNGARCARAARAARAAYGARATHAARCARMGN CARGARGARCARGARMGNYTNCARGARCARYTNAARAARAARGARGARCARATHAARGAR CARYTNTCNMGNGARMGNMGNGARYTNGARAARAARGAYYTNAAYAAYYTNTCNCCNGAY MGNCCNAARCCNGTN------------------GARACNAAYGGNATHATHAARCCNYTN ATGGARAGYGGNGAY---------GGNGGNGAYGTN---AARCCNGAYGTNAARCCNGAR CCNAAYCARGARGCNTCNMGNGARCCNCCNAGYGAYATG------------------GAY GTNAARAARGAYAGYAARGARAARGARAARGARAARGARMGNACNCCNGARAARMGNAAY MGNGAYMGNGAYMGNGAYMGNMGNMGNCAYTCNMGNTCNCCNGAYMGNCAYMGN---CCN MGNTCNMGNACNCCNGAYMGN---CAYMGNMGNGAYMGNGAYMGNMGNGCNGAYCAYGGN CAYMGNMGNTAYTCN------CCNCCNMGNMGNMGNTCNMGNTCNCCNMGNMGNTCNCCN TCNCCNMGNMGNMGNTCNCCNTCNCCNMGNMGNMGNTCNCCNCCNCCNAARCAYMGNTCN CCNCCNMGNMGNTCNCAYTCNCCN------------MGNAARMGNTCNCCNAARAARGCN GARACNGCNAARMGN---------GCNMGNTCNAGYAGYGGNAGYTCNTCNAGYGGNTCN GARGAYGAR---------TCNGGNAAYGARGAY---TCNTCNCCNGARAARAGYGGNATH CARCARMGNMGNAAYTAYMGNAARCCNGAYGAYAGYGGNAARGARTCNTCNTCNGAYTCN TCNGAYGGNGARACNMGNAAYAARMGNMGNGCNTCNCCNCCNMGNAAYGTNMGNAGYCCN TCNCCN------------MGNMGNMGNMGNTCNCCNCCNCCNTAY---MGNMGN------ ---CARAGYCCNCCNMGNMGNMGNTAYCCNTCNCCNCCNMGN------------------ ------MGNMGNATGAGYCCNCCNCAYCAYMGNMGNAGYCCNTCNCCNMGNMGNMGNTCN CCNGCNMGNYTNTCNCCNMGNMGNMGN---------AGYCCNCCNMGNTTYMGNMGNCAR TCNGTNTCNCCNMGNMGNMGNMGNTCNAAYACNCCNCCNMGNMGNYTN---CCNTCNCCN TTYCARGGN---MGNMGNMGNMGNTCNMGNTCNCCNTCNGAYTCNCCNGTNAARMGNYTN MGNCARTCNTCNCCNATGTCNCCNCCNGTNAARTCNAARAARAARMGNGTNTCNCCNCCN CCNTCNGARTCNGARGAYAGYTCNAGYTCNGAYGAYTCNTCNTCNTCNCCNCCNCCNCCN TCN------AARAARCCNTCNAARGTNAARGARCCNCAR--------------------- CCNTCNAARMGNGTNGCNCCNCCNGCNAARCARGCNAARCCNTCNAGYGAYGARAGYTCN TCNTCNGGNTCN---------GAYGAYAGYGARGARGAYTCNGAYTCNGAYCARCCNGCN TCNTCNCCNAARCARTGGMGNGARGCNACNCCN---------------CCNMGNCAR--- ------------AARCARAARCARTCNTCNCCNTCNAAY--------------------- ---------------------------AARMGNAARCCNTCNAAYAGYTCNMGNACNCAY TCNCARTCNCCN---------GTNGCNMGNMGNGAYMGNMGNCCNAGYCCNCCN------ ------------CCNACNMGNAARMGNGCNAAYTCN---MGNTCNTAYTCNMGNTCNCCN GTNMGNMGNGARMGNCCNMGNMGNMGNAAYTCNMGNTCNCCNCARCCNMGNAARCAYMGN CARMGNMGNGAYACNGAYCCNGARGGNMGNMGNGAYMGNMGNYTNCCNAGYCCNCCNMGN MGNMGNTCNCCNTCNCCNMGNMGNGAYMGNGAYGARGGNGGNMGNGAYMGNMGNMGNTCN CCNGARGTNCCNGARMGNCARGAYMGNMGNAARGARAARMGNCCNTCNTCNTCNGAYAGY AGYAGYGAYAGYAGYTCNGARGARGARGARGAYGAYAARGAYTAYAARAAY--------- ------------------------------------------------------------ ---------------------------------AARTCNAARYTNCCNCCNGCNAARCAR TTYAAYGARGGNMGNCARTCNTCNCCNAGYGCNCCNTCNAARMGNMGNTCNCCNCCNCCN TCNAARTCNACNMGNMGNGAYACNAARAAYGAYGARMGNYTNAARAGYGAY--------- AARYTNMGNMGNAARTCNGARAGYCCNGAYMGN--------------------------- ------------------MGNGCNGTNTCNCCNMGNAAYGGNAARGGNTCNTCNCCNCCN TCNTCN------AARTCNAARAARGAYAARCCNATHGARTCNGTNATHAAYAGYGAYTCN GAR---TCNGAYTCNGARAAYGCNTCNAARAARAARAARAARAARAARGAYAARAARCAY AARAARCAYAARAARCAYAARAARCAYAARCAYAARAARGARGTNGGN---------GAR AARGGNGARGAYYTNGARCARMGNYTNMGNGARAARGCNYTNATGTCNATG------CAR MGNAARAARACNCARGARTCNCARGGNCCNGAYGAYTCNGARAGYGGNAGYAGYAGYAGY AGY--------------------------------------------------------- ---------------------------------------YTNGAYYTNCARGCNGCNGCN TAYCCNYTNTTYGCNAAYMGNMGNACNMGNMGNGAYACNTTYCARGCNTGGGAYMGNACN CAYACNCARMGNCCNGARCAYYTNGTNGARYTNGGNTTYTTYTAYGCNGGNTAYTCNGAY TGYGCNMGNTGYTTYTAYTGYGGNYTNGGNYTNAARTAYTGGMGNCCNAAYGAYGAYGCN GCNTAYCARCAYGCNMGNTTYMGNCCNCARTGYAARTAYAAYCARTTYGTNAARGGNCAR GCNTTYGTNGAYCAYGTNCARMGNAGYATG---------------CARGAYAGYYTNGTN GAYGCN---------YTNGAYGAYYTNATGMGNTCNAAYGCNGCNMGNCARGCNATGGAR GARGGNTGGGCNMGNGARMGNGTNMGNGCNGGNATHACNMGNYTNGTNCARGAYYTNGGN GARGARGAYGARYTNAAYATHYTNGTNGTNGGNGCNGGNGAYATHMGNCAYATHYTNACN ACNATHGCNMGNMGNAGYMGNCAYAARAARAARAARYTNAAYTTYTAYGTNGTNGARTCN GCNYTNGARYTNTAYGCNMGNGAYATGATGYTNATGATGGTNGCNYTNGARYTNCARCAR AAYATGGGNYTNCARGARAARACNGARGTNTTYYTNGARATHCAYGGNAAYACNYTNYTN MGNCARCARACNAGYGAYTAYATHCARAARATGTCNCARCARYTNATHMGNATGGTNACN GAYTTYGAYTAYATGAARAARAARTTYTCNATHTTYGAYYTNGARCARYTNAARTAYAAR GARMGNGAYTTYYTNGARGGNATHYTNAARTTYTGGMGNAAYCARGARAARGTNAARGCN CCNTTYGAYATHAGYAARTGYTGGGAYATGMGNYTNMGNCARGTNYTNGGNGTNMGNTAY GAYAGYMGNATHAAYGCNTTYGAYTGGGAYTAYAAYATGGARATGATHGARMGNGGNGGN TCNATHATHCAYYTNCARCARTAYAARTCNTGGMGNAAYGAYGGNATHGCNTAYACNATH MGNGARGGNACNTAYGAYGTNCCNAAYMGNACNATGTCNTCNGCNATGGTNTTYAARCAY GARGGNGARMGNTAYCCNMGNMGNGGNTAYTGGGGNGAYATGGTNGTNTCNCCNTAYGTN ACNTTYGGNGTNGARACNGARGARAARTCNTTYTAYAARAARCARAAYAAYCARCAYACN AARACNGCNGARGAYGTNGCNGARTAYAAYATHACNGCNYTNATHCAYGARYTNATGACN GGNGARAARTAYGTNYTNCCNAARGTNGARACNAARGAR------AARTCNGARAAYATH GARAARCARTCNGCNACNYTNGARGARATHATHGARGAR---CCNGAYTAYGARAGYAAR GAYATHAAYGARAGYTCNAAYTCNAAYAAYGARGGNGCNAARGARGARGARGARGARGAY GTNCCNGARACNAARYTNTAYGARTGGTGYTCNYTNGARGAYGTNAARGTNACNTTYYTN CCNYTNTCNTGYGTNAARGARYTNGGNAARAARAGYAARTAYCARAARYTNTTYAAYGCN GCNTTYTTYTCNAAYAGYATGGTNCAYYTNYTNACNCCNGARGTNACNTCNYTNTTYGCN GAYAARTGYGCNATHGTNYTNGARACNGCNYTNTTYATGYTNACNYTNAARAARCCNGAR GTNCARGARTTYGTNAARAARGTNAGYGGNYTNGCNGAYGCNGCNGGNTGYAARCCNYTN GAYGCNATHGAYGAYYTNCARGAYTCNTAYGCNGCNTTYTAYTAYCARMGNTAYCARGGN TGYGARGAYTAYGAYCAYACNTAYGARCAYACNCARTGGGGNYTNGAYCCNYTNTTYYTN TAYYTNCCNTTYCARGCNGTNCAYAGYTCNGGNGAYGGNCCNCAYYTNCARGCNCCNYTN GAYTAYATHAAYAARTTYAARTAYATHGARAAYAARCARMGNMGNATHTAYGCNGCNATG GTNTCNGCNYTNGAYGAYGCNGTNGGNACNGTNTAYGAYACNYTNAARTCNTCNGGNYTN YTNTCNAAYTCNATHATHGTNTTYACNACNGAYAAYGGNGGNCCNGCNAAYGGNTTYGAY TTYAAYGCNGCNAAYAAYTTYCCNYTNMGNGGNGTNAARGCNACNYTNTGGGARGGNGGN GTNMGNGGNGTNGGNYTNGTNCAYAGYCCNYTNYTNAARCARAARGGNTAYGTNGCNGAY CARATGYTNCAYGTNTGYGAYTGGYTNCCNACNYTNTAYAGYGCNGCNGGNGGNAAYGTN TCNGAYYTNGARAAYYTNGAYGGNTTYGAYGCNTGGAGYATGYTNAGYCARAAYGGNCCN GCNATHMGNGAYGARATHYTNCAYAAYATHGAYCCNYTNGARAARAARGGNGCNATHMGN GTNGGNGAYTAYAARYTNYTNGTNGGNGGNATHAGYMGNGCNTGGGGNGGNTGGTAYCCN CCNTGGAARYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNATHYTNTGYGCNTCNGCNATHGAY MGNCCNMGNGGNGTNTCNYTNGARAARGCNTCNTTYTAYCARCAYGARACN---TTYMGN TGYYTNACNAGYGGNAARGTNYTNCCNGCNGAYCAYGTNAAYGAYGAYTAYTGYGAYTGY GARGAYGGNTCNGAYGARCCNGGNACNTCNGCNTGYTCNAAYGGNYTNTTYTAYTGYGAR AGYAARCCNTAYAARGGNCAYTAYATHAARACNTCNMGNGTNAAYGAYGGNATHTGYGAY TGYTGYGAYGGNTCNGAYGARTAYGAYGGNGTNACNTCNTGYCCNAAYACNTGYGTNGAR AARTAYGARCARGARMGNGTNMGNCARGARGCNYTNMGNMGNCARCARTCNGARGGNTAY AARGTNAARCARGARTAYATGCARCARGGNAARMGNGCNAARGAYGARAARMGNTCNAAR YTNAGYGARYTNGARMGNGARAARGAYATHYTNGTNAARGARAARGARGCNGCNGARGCN GCNAARAAYGARGCNGARGARCCNGARAARGCNGCNATHGARGARCAYAARAARGCNTGG GARYTNGTNAARGARGARMGNCARAARGCNAARGAYGCNGTNGARGCNGCNCARGCNTTY TCNAAYYTNGAYGCNAAYAGYGAYGGNAAYGTNGAYTAYCCNGARYTNATGAARCAYCAR GARTTYGAYATHGAYTCNGAYGGNACNATHAGYGARGARGARGCNAARGARTAYYTNGAR GAYAAYGARCARGTNGAYYTNGCNACNTTYACNGARAARATHTGGCCNAAYATHAARGAR ATHTAYAARCCNGARGGNGARGCNACNGAYGARCCNAARGGNGAYGGNGARGARGARATH GAYTCNGGNGTNGARGARMGNTCNGAYGTNGTNGARGGNGGNTCNCCNGAYGAYAAYGAR GARGARGARGAYGAYGAYGAYGARGAYTCNTCNTAYGAYATHGCNMGNGARAARGTNGAY GAYAGYACNGTNTCNGARGARAARGARCCNGARTAYAAYGARGARACNAARAARYTNATH GARGTNGCNGAYGARGCNMGNAAYAARTTYAAYGARGCNGARMGNAARATGAARGAYAGY GARMGNGARATHGAYGARATHAARAARTAYYTNGARATHGAYTTYGGNCCNAAYGARGAR TTYGCNCAYYTNAARGAYCARTGYTTYGARTAYACNGAYMGNGARTAYACNTAYMGNYTN TGYCCNTTYGAYAARAGYACNCARAARAAYAARAAYGGNGGNATHGARACNTCNYTNGGN ACNTGGGGNAARTGGCAYGGNCCNAAYGAYGAYAARTAYGAYACNATGAARTAYGARAAY GGNCARGGNTGYTGGAAYGGNCCNAGYMGNTCNACNCAYGTNAAYYTNCAYTGYGGNTCN ACNAAYGCNGTNACNAGYGCNTCNGARCCNAGYMGNTGYGARTAYCARTTYGARTTYACN ACNCCNGCNMGNTGYGCNGARCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GTNYTNGGNTCNAAYACNAAYGARYTNACNATHAARAARATH GARAAYACNGAYTGGGTNGGNTGYTAYTGYTGYMGNGTNTCNMGNGGNCARGARGTNATH TTYACNAARGAYGCNATHYTNCARGTNAAYTTYMGNCCNCCNAARCAR------------ ---TAYAAYGCNACNGAYAARGTNGCNYTNYTNATGGGNGCNGARGAYTAYMGNTGYGAR AARAARYTNTCNGCNCCNCARCAYGAYGTNCARACNATGGCNACNGTNTTYAARAAYYTN AAYTTYAARGTNGTNTCNYTNYTNAAYYTNACNAARAARGARATGYTNGCNGCNATHCAY GARTTYAARCAYYTNGTNGGNGARGGNGTNTAYTGYGTNTTYTAYTTYTGYGGNCAYGGN TTYGARGCNTCNGGNCARTGYTAYYTNATHCCNCCNGAYGCNCCNYTNGGNTAYAAYGAY AGYCAYTGYGTNTCNGCNGAYGCNATHYTNTTYAAYGTNYTNYTNCARCARAAYCCNAAR GTNTGYTGYATGATHYTNGAYATHTGYMGNYTNAARMGN---GARGGNMGNCARGAR--- ------YTNYTNAARCCNCCNGGNGGNGARTAYATHATGTGYTAYGGNACNTCNCARGGN AAYTTYTCNTAYGARCARGAYAARAARGGNATHYTNGTNAGYCAYYTNAARAAYATHYTN CARYTNGAYYTNAGYATGGARGAYGTNTTYAARGARYTNMGNGCNGARATGACNYTNGAY CCN---------ATHYTNAAYCARCARCARGAYGGNMGNCARGCNCCNGARATHMGNACN ATHYTNTCNGARCCNAAYMGNTCNTTYMGNGAYAARATHAAYGCNACNGGNCAYACNGAR GCNTAYYTNGAYMGNCARYTNMGNTGGGARAAYGCNCAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AAYYTNACNTAYYTN AGYYTNYTNGGNAAYCARGCNTGYCCNAAYCARYTNTCNTCNYTNGAYAARGAYGAYGAR GAYTAYCARMGNTAYMGNTAYTTYGTNATHTAYAARYTNCARAARYTNAARTTYYTNGAY TCNTCNCARGTNACNTCNATHGARYTNGCNGARGCNMGNMGNGTNGGNCCNTTYATGCAR GTNGTNMGNCCNAARYTNGARACN---GARGARAGYGARYTNGCNCCNTCNCCNCCNACN GAYTCNAARTAYACNCCNYTNCCNGCNGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TTYCARCARGGNGCNGGNYTNAARCCNGGNAARAARACNAARGGNMGNGTNAARATHAAR ATGGARTTYATHGARAAYAARYTNMGNMGNTAYACNACNTTYAGYAARMGNAARACNGGN ATHATGAARAARGCNTAYGARYTNTCNACNYTNACNGGNACNCARGTNATGYTNYTNGTN GCNAGYGARACNGGNCAYGTNTAYACNTTYGCNACNMGNAARYTNCARCCNATGATHACN AGYGARAGYGGNAARGCNYTNATHCARACNTGYYTNAAYTCNCCNGAYCCNGCNCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AARGARAARYTNCARMGNCAR YTNYTNYTNTGYGGNAARYTNAARYTNAARYTNMGNMGNYTNTAYGCNTCNCARCARGAR ATHGCNCARYTNMGNGARACNATHCAYAARTGYACNTTYGGNATHAGYGTNCARCCNGAR YTNAAYTAYYTNATHCCNYTNGARGTNTTYYTNYTNMGNCAYCCNGARAGYYTNGGNAAR ATGATGGAYATHATHGARGARGAYAAYMGNCARYTNAARMGNYTNYTNGARTGGAARGAR AARGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGTGGGGNCCNAAYGAYGCNGGNGTNGTNTTY TGYGGNTGGGAYCAYGARCCNTTYMGNYTNGGNYTNAARCAYTGYTGYCARMGNAARAGY GGNYTNTTYTAYTAYGAYYTNGARAARYTNTCNATHGARYTNYTNAGYGGNGARGGNMGN GCNGTNMGNTTYCCNMGNTTYAGYYTNGAYATGACNMGNYTNGTNTAYTTYGAYTCNCCN ATHGGNGGNGCNCAYCAYCARTGYGCNMGNYTNYTNATGATHGAYTGGCCNTCNMGNAAY ACNAARGTNGTNGTNGAYATHGTNMGNCAYGCNCCNGCNACNTCNTTYCARGGNATHTTY ATHGCNGCNYTNCCNMGNAAYATHTGGTTYGARGAYAAYGTNCAYYTNGCNTTYTCNACN GCNTGGMGNAGYGCNACNAARGCNATHATHGTNAAYACNAAYACNGCNGAYGTNAARACN ATHAAYGAYAARAAYATGGAYATGAAYYTNACNGTNYTNAGYGTNAAYAARAAYTGYGTN YTNTGYTCNTCNTCNAAYYTNACNACNCCNAGYTAYYTNGTNYTNGCNCARYTNACNAAY GCNGGNAGYCCNCARACNGCNGARTGGATHTAYCCNGAYGGNCCNCCNGGNCARYTNGAY TGGYTNTCNTCNTAYCARGTNYTNACNATHACNCCNACNGGNGGNMGNGTNTCNYTNATH AAYGCNAAYYTNGAYTAYGARAGYATHYTNTGYYTNCCNTCNAARCCNACNGAYGGNCAY YTNCCNCCNYTNATHGTNTTYTCNCAYGGNGGNCCNCAYGTNGGNTTYGAYACNTCNTAY AAYGTNATGACNAAYTTYTTYTGYYTNTGYGGNTAYGCNGTNGTNATGGTNAAYTAYMGN GGNTCNTGGGGNTTYGGNCARGAYTGYATHGARTCNYTNYTNGGNTCNATHGGNGAYGTN GAYGTNAARGAYGTNGARGCNGCNATGCARYTNGCNATHTCNACNGGNCARGTNGAYAAR TCNMGNGTNTTYYTNGCNGGNGGNTCNCAYGGNGGNTAYYTNACNACNCARYTNATHGGN CARTAYCCNAAYTCNTTYAARGCNGCNGCNGTNMGNAAYCCNGTNACNAAYYTNGTNTCN ATGTAYTCNACNAGYGAYATHYTNGAYTGGATHTTYGTNGARGGNGGNTTYCCNTAYGAY ATGACNTGYATHGCNGAYGAYAARAARYTNCCNGARYTNTGGAARMGNTCNCCNYTNTGY CAYATHGAYAARGTNACNACNCCNTAYTAYAARMGNCAYATHCCNGTNMGNTGYYTNGCN TAYCCNTCNAGYAAYCAYAGYYTNTCNGARGTNGAYGTNGARTCNGAYAGYYTNGTNAAY TCNATGGTNTGGTAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GGNGGNTCNCCN ACNYTNTTYGGNGTNGCNTCNGTNATHAAYCAYGTNTCNGARYTNYTNGCNTAYTTYATG ACNGGNACNTTYATHGCNAARTAYGGNCAYGTNAARYTNYTNTAYGCNGGNYTNATHGGN AAYATHATHMGNTTYYTNTAYATHTCNTTYYTNAARAAYCCNTGGTGGGCNYTNCCNTTY GARTTYGTNCARGGNYTNACNCCNGCNGCNGTNTGGGCNGCNTCNTGYGCNTAYATHACN CAYGCNATHCCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARACNGAY GAYCARAARACNGTNGTNGCNGTNGARAARCCNGCNGAYGGNGARGAYACNGAY---GCN ATHATHGAYTTYGTNGARGAYAARGAYYTNAGYAARGGNCAYTAYACNTAYCARGGNGAY ATHTAYACNYTNCCNGGNAARAAYACNAGYCCNAGYGARAAY---YTNGAYGARAAYCCN ATHATHTCNMGNATGAARGARATGGTNGTNGARAARTCNMGNACNAAYAGYTCNGTNTCN TCNTCNMGNGAYTAYTCNGCNAAYCAYACNCCNMGNTCNTTYAARTCNACNTCNGCNGCN GGNGGNGAYATHATGGARACNCAYCARGAYAGYAGYGTNGAYAARGGNATHGTNGARYTN MGNGAYAGYACNAARGCNGCN--------------------------------------- ---ACNACNTTYGAYGARATHAAYAAYGCNGGNAARMGNATHACNGCNTCNGCNTTYGAR TTYYTNAAYACNTAYYTNTCNGAYGAYGARGGNGGNGAYGGNCARATG------------ ------------------------------------------------ATGATHGCNMGN GAYCCNGARCCNCARYTNCCNTCNATHAAYTGYGAYYTNGCNGAYYTNAAYATHTCNAGY AAYGARTTYGAYCARYTNATHYTNCAYAGYYTNMGNGAYATHCCNYTNTCNATHGAYACN AAYATGYTNGTNGAYTCNACNACNCARGARACNACNTGYGAYAAYGTNGGNGCNAAYGTN TCNGTNYTNCCNGARYTNGARCCNAAYTTYYTNTCNTTYTTYCARAGYYTNCCNATHCCN AAYCCNGGNTCNTCNYTNTTYCARACNGCNGAYCAYAAYGTNAGYCARMGNGAYGGNGAY GCNACNCCNCCNTTYTCNGGNGGNAGYACNCCNCARAGYCARTCNMGNGCNCCNTCNCCN ACNTGGAGYGARAGYAGYGGNAAYATGAGYACNAGYAGYYTNTCNAGYTCNYTNAARATG ACNCCNGARAGY------------AARCCNGTNCCNMGNCAYAARMGNCCNTCNCAYMGN MGNGCNGARGTNAARMGNMGNGAYAARATHAARACNACNYTNGAYGARATHAARATGAGY GTNCCNTCNYTNCARGAYAARGGNAARYTNAGYGARTCNGCNATHYTNTTYAARNNNNNN NNNNNNNNNNNNCARYTNAARGAYGGNGTNTCNGAYMGNGGNAGYAARGCNGCNGARYTN MGNMGNGARATHCARAGYYTNAGYGARGARATHCAYTCNTTYCARGARACNYTNCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TCNAGYAARTCNTCN CCNTAYCCNACNCCNATHCAYGCNAAYGARMGNYTNMGNAGYCAYAGYAGYMGNYTNCAR TTYTCNTCNCAYMGNTCNCCNCAYTCNGGNAAYYTNCCNCAYTAYGAYGGNGAYAAYGTN TGYYTNGAYAAYACNGARTCNATHGAYAGYTTYAAYTCNGAYGARGAYAGYATHAAYTGG GGNATHGARGARGARGARGGNAAYCARMGNYTNTCNGCNYTNCCNCAYYTNAAYCARTCN YTNTCNGAYYTNCAYTTYMGNCARTCNYTNATGCARMGNATHCARGARTGGTCNAGYTTY GCNGARGARTAYAAYAARTCNATGTCNGTNACNCCNGARGTNTCNCCNATHMGNTAYGTN MGNMGNAGYMGNTCNYTNGAYMGNCAYYTNAGYGAYTCNTCNGTNATHGCNACNGARTCN GARATHCCNTCNTCNAARCCNYTNGARATHGARCCNGTNACNGARAARAAYYTNGARACN YTNGARTAYGARYTNCAYGAYATHCARGGNGARTTYGARTCNATHACNTCNMGNYTNCAY GAYYTNATHGARCARCCNACNCCNYTNTCNCAYGCNCCNATGTCNTCNTCNTAYCCNGCN GCNTTYACNTCNAARAARTCNGCNTCNTCNTCNAAYAAYAAYAARGARTCNCCNYTNGCN TCNCCNCARAARMGNMGNYTNGARAGYMGNAGYGCNTCNTCNTCNTCNTCNYTNCCNGGN AAYAGYACNGCNTCNYTNMGNAARATGAARACNAARTGGGARAARGTNCCNGGNTCNGCN TGYTCNGAYTGYAGYMGNAGYTCNMGNGGNAGYAGYGTNGARTAYGTNTGGGAYATGGCN GAYTAYTCNCCNAAYTCNACN---AAYGCNTCNGCNGAYMGNTCNMGNACNAGYCCNGCN ACNGGNMGNMGNGTNTCNAAYGTNTGYAAYATHAAYCARCCNGTNTCNGTNYTNGAYTAY TGYYTNCARGARTGGAARGGNGAYACNGCNAARGCNTCNGCNATHMGNCARGGNTAYCAY CARATHCCNTCNMGNATHAAYTGYCARMGNATGTGYGTNGTNMGNGGNGAYAAYTAYTGY GCNYTNMGNAGYACNYTNTTYCARGTNYTNGTNGARGGNATHMGNATHGTNCCNAGYTCN TGGGGNATHATHGGNATHATGGAYMGNYTNCAYGAYCAYTTYGARGAYCCNTCNATHCAR ATGTCNGCNTGGAAYTTYGCNAAYMGNYTNCCNAGYCAYTGYMGNGAYAARYTNGCNTCN ATHTCNAARTGYGCNYTNTCNYTNTAYGCNACNGTNGARGARGTNTGYAAYYTNTCNACN MGNGARGARMGNGARAARMGNACNATHAAYYTNTTYAAYGCNAGYTCNACNTTYGAYYTN GARYTNATGGARGGNGTNAARGTNATGATGYTNYTNCARYTNGTNTCNYTNMGNCARAAR ATGYTNGAYGGNGARGAYATHCCNATHTTYGGNCAYYTNYTNTTYGCNMGNGAYACNTCN GARTCNGTNGCNAAYTTYATHACNAAYCAYYTNAAYAARGTNGGNGAYACNGGNGGNYTN GARCARGTNGARATGTGYYTNYTNGGNTAYACNYTNGGNGTNAGYGTNAAYGTNYTNMGN YTNTCNCARACNGGNCARGAYGAYTTYGCNTGYTGYTTYCCNGAYGAYATGCCNTCNGAY ACNCCNCARGTNGCNYTNYTNGCNGARGAYGAYMGNCAYTAYAAYGTNCCNYTNCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR GAYYTNGARTTYAARCCNGAYGTNGTNTGGCCNTGYTCNGAYACNATHACNAGYTCNGCN ATHAGYCCNTGYTCNTCNCAYYTNGCNATHGGNYTNGCNAAYGGNAAYGTNGCNGTNTGG GAYTAYCARATGGGNYTNCCNAARGCNGTNYTNACNGTNTCNGGNAAYGCNGGNGTNAAR GARYTNTGGTTYYTNGAYCCNAGYYTNTTYCCNTCNGAYCCNYTNGARTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARMGNAAYTTYYTNAAR GTNCARGARGAYMGNMGNACNYTNCARCARGARATHACNGARATHCARGCNGAYGTNMGN TCNATHGCNGCNGARATHGARAARACNCAYMGNACNGAYCCNTGYTAYATHGAYYTNGTN AARAARGARCAYGGNGTNYTNGTNAARGARAARGAYATGTCNGCNMGNYTNAARGCNYTN GAYMGNTGYGARMGNGAYYTNTTYTCNYTNYTNAGYATGTAYGTNMGNGARAGYCAYGAR AARGARMGNGCNMGNGCNGARMGNACNAARTAYTGGTCNGTNATHGGNTCNATHGTNGGN GCNGTNATHGGNATHACNGGNTCNACNATHAAYAAYCAYMGNMGNYTNAARGARATHMGN TCNATHGTNACNGARTCNGGNGARAAYACNGCNGARTAYAARCARATHGCNGAYAAYATH YTNGCNAGYYTNTCNTCNAAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNCCNACNTAYTCNACNCCNCCNATGTCNTTY CAYAARGTNMGNYTNGARTCNAGYTCNACNGGNTCNTCNTTYCCNGCNGAYTTYACNAAR CCNGTNCCNYTNGCNGTNATHTCNCCNGGNMGNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARCARTTYGAYMGNGARTAYGAYGAYGCNYTN TCNAARMGNGARGARAARTAYAAYGGNAAYTGYAARGTNGCNGTNTCNTTYGAYAAYTAY AARMGNAARCAYATGCARTCNGARTAYCARAAYGARGAYGTNGARGAYGAYGAYGAYTTY TAYGARGARGAYYTNCCNGARCAYCCNAAYMGNACNCARTGGGARAAYGGNGCNCCNTCN ATHGGNGGNAARGGNTAYGTNAARCARGGNGAYAGYATHATHACNAARCAYGAYAARGTN ATHTGYGGNMGNMGNAAYGCNCARMGNYTNATGCARTTYCCNCCNGAYTTYGAYAGYGGN GAYGGNGARGGNATGGAYATGCARYTNCCNAAYMGNGTNTAYAAYAARYTNAARCARCAY TCNYTNTCNGARAAYAARAARAGYCAYAARGTNYTNGARAARAARGAYCAYTCNACNGCN ATHAARGCNGTNGAYGARAARACNMGNATHYTNATHTTYAARATGATHAAYTCNGARTTY YTNACNTCNGTNGAYGGNGTNGTNAGYGARGGNAARGARGCNGTNGTNYTNAARGCNGCN GGNGGNMGNAARGAYAAYATGGTNYTNCCNCARAAYGTNATHYTNAARATHTAYAARACN TCNATGAAYGARTTYAARACNMGNYTNAARTAYGTNCARGGNGAYTAYMGNYTNTCNAAR GAYACNTTYAARAARTTYAAYGCNMGNAARYTNATGCARATHTGGGCNGARAARGARTTY YTNAAYYTNMGNAARYTNCAYMGNCAYGAYGTNYTNTGYCCNGTNCCNYTNATGCARAAR AARCAYGTNYTNGCNATGAGYTGYATHGGNGGNGARACNCCNGCNCCNAARYTNAARGAY GTNGTNTTYAGYACNGARGAYTTYCARGAYGCNTTYGARCARACNGTNCAYYTNATGAAR YTNATGTTYGAYAARTGYAAYATGGTNCAYTGYGAYTTYAGYCCNTAYAAYYTNYTNTGG CAYAAYAARAARGTNTGGGTNATHGAYGTNGGNCARGCNGTNGAYMGNGAYAAYCCNMGN TCNAAYTCNTTYYTNTAYMGNGAYTGYAARAAYATHTCNGARTTYTTYAARCARGGNGGN GTNTAYGGNGTNCCNTCNCCNGARGARYTNTTYAAYGARATHACNAARTAYAAYTTYGAR GGNGARGGNAARGTNTTYGARTCNCARGTNCAYMGNTAYGAYGARGARGGNTAYGCNTTY GAYTTYTTYTTYGARYTNTCNGARGARGCNMGNTCNCARMGNYTNATGAAYGCNGAYGGN AGYGAYAGYGAYAGYGCNGARGAYAAYGAYGAYGAYGGNGAYAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CARAARGARMGNAAYMGNAAYAARAARGGNGTNTGGGCNCAYTCNCARATGATGAAY CAYCCNGTNGCNCCNCCNGTNAARCCNYTNMGNMGNGAYATGGGNCCNACNCCNCCNTCN CARCCNMGNCCNAARCCNMGNCCNCCNCCNCCNAARMGNGAYACNGGNCARCCNCCNCCN GAYYTNGARCCNYTNGAYTCNGAYGTNATHYTNATHMGNCAYAAYCAYYTNCARCCNGAR GAYYTNMGNYTNACNAARACNAAYAARGTNGAYGAYAARGARGARAARMGNMGNAARTTY TGGMGNGGNGTNTAYMGNAARAARGARGTNYTNTAYTGGACNAAYYTNMGNCCNTTYATG TTYAAYGTNGGNATHTCNAARMGNGGNCARGGNGTNGARATGGTNGTNCCNTCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGACNGARGTNGAYGTN GGNATHACNGARTAYYTNGGNTCNYTNACNGARTCNTTYTCNGCNGTNATHAARCARMGN TAYTCNGAYTTYATHGTNAAYGARATHGAYGARGAYGGNAAYGTNGTNCAYYTNAARAAR GTNACNCAYGARGARGARAARGAYGAY---------GGNGARGARGARAARTAYCCNTCN TCNAGYGTNYTNAGYGARTCNGAYAARGCNCCNATHCARAARATHGTNACNGAYMGNAAY MGNGAYGCNTCNCAYACNATHYTNGCNCCNGARGAYAARACNYTNMGNACNAARATHCAY YTNGCNATHAARGARMGNTTYTCNCARATGGARACNTCNACNGTNGAYGAYGARACNGGN AAYAARGTNATHAARGTNGCNTGGMGNAARGGNAARACNMGNGAYGTNATHMGNGAYGAR TGGCCNCARTCNAARAARTCNTGYMGNTAYGTNMGNTTYGTNYTNTAYAARGARAAYAAR GAYACNATGGAYGCNATHGGNYTNATHGCNAARAAYYTNAARGTNMGNGARAAYATGTTY CARTAYGCNGGNAGYAARGAYAARMGNGCNAARACNACNCARGARATHACNGCNCAYMGN ATHCAYCCNAARAARYTNGCNAAYYTNAAYAARGTNYTNTGGAAYATGGGNYTNGGNGAY TTYMGNTAYGTNGAYCARCCNYTNCARYTNGGNCARYTNTCNGGNAAYMGNTTYACNATH GTNYTNMGNAAYATHCARGCNAGYTGYGAYGTNGTNGAYTCNGCNYTNACNTCNYTNAAR GTNACNGGNTTYATHAAYTAYTTYGGNATGCARMGNTTYGGNACNACNGCNGTNCCNACN CAYMGNATHGGNAGYGCNYTNYTNAARGGNGAYTGGGAYAARGCNATHGAYYTNATHYTN GCNCCNMGNAAYGAYATHCCNGCNAARGAYAARTTYCARAARAARTGGGCNGARACNAAR GAYCCNACNGCNACNYTNGAYGTNACNCCNMGNTAYTGYGGNYTNGARMGNAAYATHYTN GARGGNYTNGCNAARAARCARAARCCNTTYAAYGCNYTNGARMGNYTNCCNMGNAAYACN MGNYTNYTNTAYATHCAYAGYTAYCARTCNYTNGTNTGGAAYAARATGGCNTCNAARMGN YTNACNCARYTNGGNCAYAARGTNGTNGTNGGNGAYYTNGTNATGGCNMGNCARGCNMGN ACNGCNAARGGNGAR------GARTCNTCNTCNCCNGTNGTNGTNACNGARGAYACNGTN AGYATHTAYACNYTNACNGAYGTNGTNYTNCCNYTNCCNGGNTTYGAYGTNGTNTAYCCN CARAAYCARGTNTGYGARTGGTAYAARGAYYTNYTNTCNTCNGAYGGNYTNGAYATHGAY AAYATGAARMGNTCNCARAARGAYTAYTCNYTNTCNGGNGCNTAYMGNCAYYTNGTNGTN ATHCCNACNGAYGTNTCNTGGACNCARCCNACNTAYGAYGAYTAYACNCARCCNYTNACN YTNAGYGAYTTYGAYGTNATHAARGARGARACNYTNAARGAY---TGYGGNGARTCNGGN ACNCARMGNGCNGTNGTNYTNCAYATGTCNYTNCCNTCNTCNTGYTAYGCNACNATGGCN YTNMGNGARGCNATGMGNATHGAYACNTCNTCNTTYCAYCARTCNTCNYTNAAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGGCNGAYGARYTNCCNYTNTTYCCNAAR GCNACNTCNATGTTYYTNCAYAGYGGNAAYATGATHAAYTGGAAYMGNYTNAARMGNMGN CCNAAYYTNTCNTCNTCNGAYGARYTNTGYGARGTNATHGCNGAYACNYTNCAYGCNTAY GTNGARGCNTCNGAYAARACNGARYTNCARTAYGTNACNGARGTNTAYAARGTNAARTCN GARAAYGTNGARGTNATHGARGARAGYGARMGNGGNGAYGTNAARATHACNGTNAARGTN TTYATHTGYGAYTCNCARCCNCCNAGYGTNATHGGNGAYGCNGTNACNAARGTNYTNAAY GARYTNGGNACNACNTTYGTNGARACNYTNYTNYTNGCNGTNMGNCCNAAYAGYGGNGAR GAYCAYGAYCCNGARGARGTNGTNAGYYTNTCNACNGTNGARGGNTAYTGGAARGCNATG GARGARYTNGTNGCNAARGAYAARGTNYTNTCNYTNGGNATHTGYGAYTTYGGNAARGAY GGNYTNGARGCNYTNTAYAAYTGGGCNCARGTNAARCCNTGYGTNGAYCARGTNAAYYTN GARTCNTGYTGYGTNYTNCCNAARGAYYTNACNGARTAYGCNAARAGYATHAAYGTNCAR YTNYTNACNCAYAAYGAYMGNCCNGCNTTYATHACNAARGARYTNYTNCARGARAARATH CARAGYGTNACNACNGARMGNGAYAGYGAYGCNTGGGCNCCNGARTGGGTNGTNMGNTAY TCNGGNATHYTNAARTGYMGNGGNATHATHAARACNAARGGNTAYATHTTYCAYGCNGCN MGNGAYAAYAARAARMGNATHYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AAYGGNTGYTCNGARMGNAARMGNAARMGNMGNAGYMGN TGGAAYACNGAYAAYGAYGAYAARACNGTNATHCCNGGNATGCCNACNGTNATHCCNTCN AAYYTNTCNGARGCNCARCARMGNCARTAYGTNGTNCARYTNCARATHGARGARATHACN MGNAARYTNMGNACNGGNGARYTNGGNATHCCNTCNAAYCCNGARCARMGNTCNCCNTCN CCNGARCCNATHTAYAAYAAYGARGGNAARMGNYTNAAYACNMGNGARTAYMGNACNMGN AARAARYTNGARGARGARMGNCAYMGNYTNATHCARGARGCNYTNAARYTNAAYACNGAY TTYAARCCNCCNAGYGAYTAYAARCCNCCNGTNGTNMGNGTNAAYGAYAARGTNATGATH CCNCARGARGARCAYCCNGARATHAAYTTYGTNGGNYTNYTNATHGGNCCNMGNGGNAAY ACNYTNAARACNYTNGARAARGAYACNGGNGCNAARATHATHATHMGNGGNAARGGNTCN GTNAARGAYGGNAARATHGGNMGNAARGAYGGNCARCCNYTNCCNGGNGARGAYGARCCN YTNCAYGCNTAYGTNACNGCNAAYAAYCCNGARAAYGTNAARAARGCNGTNGARCARATH AARGARATHATHAARCARGGNATHGARGTNCCNGARGGNCARAAYGAYYTNMGNMGNCAR CARYTNMGNGARYTNGCNYTNYTNAAYGGNACNYTNMGNGARAAYGAYGGNYTNCARAAR YTNMGNCARATHGCNGARAGYCARACNATHGTNACNAAYACNATHATHTGYACNATHTGY GGNGGNACNGGNCAYATHGCNCARGAYTGYAARCARAARMGNCCNGGNGAYACNTTYMGN ATGCARCARATGCARAAYCCNGCNGAYMGNGCNAARATGGAYAGYGARTAYATGTCNYTN ATGGCNGARYTNGGNGARGGNCCNCCNCCNCCNAARTCNGARACNCAR------GCNCCN AAYAAYTTYGGNCARAAYCARTCNCCNTTYAAYMGNCCNYTNYTN---AAYCCNCCNCCN AAYCCNATGGCNATGAAYTCNCCNTGGCARATG---CCNGGNAAYMGNCCNCCNATGTCN AAYCCNGTNCCNCCNCCNCCNTCNAGYTCNGGNCCNCCNYTNYTNAAYMGNCCNCCNATG GGNATGCARTCNACNGCNCCNCARATHAAYCCNATGGGNMGNYTNCCNATGCCNYTNATG TCNAAY------------AAYCCNGGNATGCARCARGGNCCNATGYTNCCNCCNCCNCCN GGNCARCARCCNCCNCARCARATGGGNAAYATGCARCARCCNCCNCCNCCN--------- ---------------CARCARCCNCARCARCARCARCARCCN------YTNMGNCCNTGG CARCARCCNTCN---AGYCARTCNCARCCNATGATGAAYCARGGNGGN------------ ------------------ATHTCNTCNAGYGCNGGNATGGGNATHCCNCCNCCNCCNCCN TCNATGATGACNGCNCCNCCNCCNCCNCCNGTNAGYACNCARGGNCAR---GTNCARCAR GCNCCNCCNCCNTGGATGCARCARCARCARCARCARCAYGGNAGYATGGGNYTNCARCAR CARCARCCNCCNCCNCCNCCNCCNCCNTCNACNTCNGCNGCNCCNTGGCARCAR---CAR CARCARCARCARCARCCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AAYTCNNNNNNNNNNNNNNNNGGN GGNTTYTCNGARTTYGCNTTYAARTTYCCNAARYTNTGYGARTCNAARAARAARACNGGN TGYGCNYTNYTNTCNATHTCNACNCCNTGYGCNTCNGTNMGNACNTGYCCNCCNACNAAR GTNYTNCCNTTYYTNTAYYTNGGNTGYGARGARGAYGCNCARTCNGCNGAYGTNYTNMGN ACNTGYMGNGTNAARTAYGTNYTNAAYGCNAGYCARACNGCNGCNGAYACNCCNCAYTGY AGYTCNACNCAYTAYYTNAARATHCCNATHGARGAYTCNTCNAAYGARAAYATHGTNGAR TGGTTYCARACN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY CCNYTNACNATGGARCAYYTNYTNGARCARCARTGGGARGCNGGNGCNCARTTYYTNATG GARCARAGYGARCAYTTYGAYATHTCNTCNYTNYTNAAYTGYYTNCAYCAYTAYAARTCN GAYATHMGNCARYTNGARGGNGARGTNMGNGAYYTNACNTCNCARMGNGAYCAYYTNATG GCNGTNAAYGCNMGNYTNTCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAY ACNYTNTAYTAYGAYTCNMGNTGGATGTGGCARCAYGTNTCNYTNACNTGGYTNAGYGCN YTNYTNATGYTNACNGCNCAYTTYYTNACNCCNCARTAYYTNCAYYTNYTNCAYAARAGY GCNMGNCAYYTNGGNMGNTGGCARMGNATGGARGCNMGNCAYGCNCAYGTNCCNTAYAAY GCNTGGTCNGARYTNCARGTNTGGCCNCARGGNGCNYTNGTNAARCAYGTNMGNGGNYTN TTYAARGCNGARGGNATHAAYGTNACNGCNGARCCNGGNAAYAGYYTNCAYAGYMGNTTY TTYYTNYTNTTYCAYCARCCNYTNMGNGTNATGAAYTGGYTNGTNTTYYTNACNTGYYTN GTNATGGCNTAYCARGCNTTYMGNYTNGTNCARACNTCNGARTGGAGYCAYATHATHTCN YTNGCNYTNYTNATGTTYTGYAAYTTYTAYACNYTNTTYAARYTNATGMGNGAYTGGTTY ATHATGGGNAARATHTAYAARGAYCAYGAYTAYGTNGTNTCNAAYTCNGAYGAYGCNGAY GARGARTTYGTNGAYGCNTCNGARGARAAYCARCARACNACNGTNGCNATGGCNAAYGGN GAYATHCAYAAYATHYTNCARGGNYTNGAYATHAARATGAARTCNAARACNTTYGARGAY YTNAGYTAYGCNATGACNMGNYTNAAYGARYTNAARATHATHCAYCCNYTNGARTCNGGN ATHTAYTGGMGNATHTCNGARACNTCNTTYAAYYTNGCNCARGARGARATG---YTNCCN GCNGARCAYCCNYTNGARMGNCAYAARGARYTNATGTCNYTNGCNAARGARGCNGTNGAR AARTCNGTNAARYTNAAYCCNAARTCNGGNAAYGCNCAYMGNTGGGCNGCNATHATHYTN GGNAGYYTNACNCARTAYATGCCNACNCARGAYCARATHAARAGYGCNTTYATHATHAAR GAYCAYATHGARACNGCNATHAARTAYYTNCCNGAYGAYTAYYTNYTNTAYCAYATGATG GGNMGNTGGTGYTAYTGYGCNTAYATGYTNACNTGGGTNGARMGNAARATGGCNTCNGCN YTNTTYGCNACNCCNCCNACNGCNACNYTNGARGARGCNATGGAYAAYYTNAARAARGCN GARACNYTNAAYCCNYTNTCNTCNATHTCNAAYCARYTNTAYYTNGCNAARGCNTTYATH GCNAARGGNGAYTAYAARACNGCNGTNGAYTAYYTNAARGCNGGNGARGARYTNTAYGCN ------------------------------------------------------------ ------GGNMGNACNAARTAYACNGAYGARGAYGAYTTYAARATGYTNATGTTYATHCAY TGYTAYAARMGNGTNMGNGGNMGNACNYTNTGGCARGAYATGGARAAYAARCARGTNACN AAYCAYTCNTGGGARAGYATGAARTGYMGNTTYYTNMGNGTNATHYTNCCNAAYATHGAR ATGTAYGAYATHCCNTCNCARYTNMGNGAYMGNYTNACNGGNCCNGTNAARCCNGARMGN YTNCARCARCCN---CCNACNGAYGCNCCNGAYGAYATHTAYGAYGAYGCNATHTCN--- ACNTCNGARYTNACNATHTAYGAYTGGTTYCAYGGNAARATHAAYMGNAARGARGGNGAY AARMGNGTNCARTCNATHGGNTCNATHGGNACNTTYYTNATHMGNGARAGYTCNGGNAAY ACNGGNAAYTGYTTYCCNTAYACNYTNGTNGTNAARTCNAARGAYGARGTNAARAAYYTN MGNATHMGNAARMGNCCN---GAYTCNAARTAYGCNATHGGNAGYGARMGNACNGAYGAR ATHTGYTTYCARCAYATGTAYGARYTNGTNGAYCAYCAYMGNGARAAYTCNGTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CCNTCN GAYTAYGARCCNGCNGTNGTNYTNGAYAAYCARAAYCCNGAYGTNTAYTGYATHMGNGCN YTNGTNMGNAGYTGYMGNAAYGARGARAARYTNGCNYTNMGNGAYYTNGAYGAYGCNYTN GCNTTYAGYCCNAAYCAYGTNAGYTGYYTNGTNGTNMGNGGNGCNATHACNMGNCCNTGG TCNCCNAARTAYCCNGGNGAYATHCCNMGNCARAAYAARTAYYTNMGNAARGCNGARAAR YTNAAYCCNGAYTCNCARTCNTAYTTYAAYGTNGAYAGYTTYAAYCAYCCNTGYGTNCAR GAYTTYTAYGAYMGNATGYTNTTYACNYTNYTNGTNCCNCAYACNATGACNGARATHAAY YTNACNCCNAAYAARCCNAGYAARAARCARATGGAYTCNAGYCCNGARYTNTTYMGNAGY GARTCNAGYMGNTCNYTNAAYTCNMGNATGGGNTCNCCNACNMGNCARGGNTCNCCNACN GARMGNYTNGAYCCNTTYMGNTGYGGNACNCCNTCNATHACNGARAAYMGNCAYGCNACN MGNMGNMGNYTNGAYTAYGGNGARGCNGTNMGNMGNCAYAAYTCNMGNCCNAARACNGCN ACNGARTAYATGGCNGTNYTNGARAARGARMGNATGAARMGNATGGARAAYTCNACNMGN GCNCARACNGCNACNGCNTCNTCNTCNATGGARMGNTGYCARTCNGCNCARAARTCNGTN TAYCAYTCNTCNACNACNAAYTCNAGYGGNMGNACNACNAARACNAARAGYACNAARGCN TTYGTNTTYGARACNCCNAGYAAYTAYTCNATHCCNGTNTTYCARCCNATGAAYATHGCN GARGCNCCNMGNATGTAYTAYMGNCCNTGGMGNGGNGAYAARYTNCCNGTNGGNGAYGTN CCNCAYCCNCARCCNTCNCCNGCNTTYTAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AGYMGNYTNAAYMGNAAYYTNGAYCAYAARYTNTCNGAYGAR TCNCCNCAYATGCARGAYGTNTGYGTNTCNMGNGCNGTNCARAARGGNATGYTNGCNYTN ATHAARGCNATHATHCAYGGNYTNGGNCARACNATHACNAAYCAYGGNYTNGGNGGNATG GCNTCNGCNTAYATGGTNYTNGARGTNGCNCAYACNCAYTTY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TGYGCNATGGGNCARCARCCNTCNMGN CARGAYATHYTNCAYAARGARGTNAGYGAYTCNAARATGMGNAAYTGGATGTGYGCNAAY ATHGCNATGMGNGAYACNTCNAARGCNYTNGCNGTNTGYYTNCAYCAYMGNATHGCNCAR ATHCAYAARGAYATGTCNCARGCNGTNGGNMGNGGNMGNCAYTGYACNAARAAYTGYTCN TGGAAYMGNGCNGAYTGGTGYTCNGTNTGYGARMGNTGGGCNMGNGARATHATHGCNATH TGYGARCCNGAYTAYMGNCCNMGNATHAAYTGGTCNMGNYTNAAYTCNTCNCARTGGCCN CAYAAYCCNTAYGARGTNGCNMGNGCNYTNATHCCNAARGCNCAYMGNYTNTAYTAYAAR TGYTCNGARTTYCAYGARGAYTTYMGNTTYAGYYTNAGYTTYATHGARAAYTGYACNGAR ATHCCNGTNTCNMGNTCNYTNTGYGARAARGCNTGGCARTTYMGNAGYMGNYTNAARMGN AARAAYAAYACNATGMGNATGAGYYTNGGNGAYYTNGARGAYGGNGTNTCNTGYATGATH GCNYTNGTNTCNYTNCCNGTNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AARAARAAYGTNATHGARGCNATHACNGAYYTNGAR AAYGGNAARCAYGTNATHAGYGGNAARGTNGTNGAYGTNACNMGNAARACNAGYGGNGGN TTYAAYATHGGNCAYGTNATGATHAAYGGNAGYGAYMGNTGGACNGGNGARATGATHGAR ATHGARTTYCARAAYGARTAYYTNGTNATHTAYYTNATHGARAAYGGNMGNMGNGGNGAR GTNCARGGNTGYGTNCCNGAYYTNATHGGNYTNGTNGAYTCNGARACNGGNGARCCNATH ACNGCNGARGARYTNMGNTAYGGNATGATGGTNGCNGTNGTNYTNYTNCCNTCNTGYAAY YTNYTNMGNMGNCCNGARGCNYTNAARTGYGTNGGNCCNCARGCNTTYMGNTAYAAYGAY GAYATGAARTTYGTNCCNTTYMGNGARMGNAARCCNATHAARCCNGTNCCNYTNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARTCNCCNACNAAYCCNGGNACNTTYACN ATHAGYCCNCCN------ATHACNACNTCNGTNCCN---TCNTCNYTNCCNGCNAAYGCN ATHTCNCCNAARCCNGAYCCNAAYAARCARAARAARGTNCCNCCNCCNCCNCCNCCNMGN AARGGNAGYMGNCCNACNTCNATGACNGGNYTNGAYYTNAAYGGNACNCARCARCARCAR GARCARCARCARCARGARCARCARGARATGCCNCARTTYGTNGGNGGNATHYTNGGNCAR CAYMGNYTNTCNGGNGGNCCNYTNTCNTCNACNCCNAARCCNGCNTCNCARCARMGNGCN YTNTCNACNTTYGARAARGAYATHGCNTCNGGNATHTAYGCNAAYYTNAAYMGNCCNGAY YTNCARAAYCARAGYAGYTCNCCNCARCARATGATHGGNMGNGCNAAYGCNGTNAGYGTN AGYACNAARCAYACNAAYAAYAAYAAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARGARMGNACN ACNGAYACNATHAAYGARACNGAYAARTGGTAYAARATHAARGCNGGNYTNTTYYTNACN GCNGTNACNGGNTTYTCNGTNTTYTCNGGNTTYGGNATGAGYYTNGGNATGGCNAARAAR CARGAYCCNMGNCAYTTYGCNAARGGNYTNGCNGGNTCNAARGARATHCCNGARAGYGGN GTNGCNYTNGCNTCNMGNGCNYTNGCNMGNGCNTCNYTNTAYACNATHACNGGNTAYGGN YTNTTYTGYTTYGGNGTNTGGAARYTNATGGGNGTNAAYAAYTTYGCNGARTTYMGNGAR AARGTNGGNAAYGCNYTNCCNMGNYTNAARMGNAARGARAGYACNGGNMGNAAYGARTTY GCNTCNATHMGNGAYYTNTTYCARTAYYTNATHGAYGARGAYGAYAARTCNAARGCNYTN AARGCNGCN------GARGARGARTGYGARTAYTAYAARCARMGNTTYAAYTGYYTNAAR ATHGTNCARGARMGNATHGCNAAYGARYTNACNCARTAYAARAAYMGNTGYYTNGGNGTN GAYACNATHCARTCNYTNYTNAARGARTCNMGNCARGARAAYGCNAARYTNTCNAARCAY GTNAARAGYYTNGARACNGAYATGTCNYTNYTNCARAARMGNYTNGARAARAAYGGNYTN TCNAARAGYATHAAYACNCARGAYTCNGARYTNTTYGCNCCNAGYGCNTCNAARCARACN YTNGAYAAYYTNGCNAARGARACNGTNMGNYTNMGNTCNYTNYTNAARCARGAYAAYGAR YTNTTYATHAARAARTCNGCNGAYGARATHGARGARATGAARTTYGCNYTNGARGARGCN GAYTCNGARATHAAYGARYTNAARAAYAARATHAARGAYATGGARGAYGTNAARYTNAAR YTNATHAGYGGNTAYGARCARACNATHGARAARYTNACNAARGARATGCARGARGARAAR GARAAYTTYGARGAYGARCARMGNAARAAYGARAGYYTNTCNGCNAGYTCNAGYGCNGTN CARGARYTNAARAAYYTNYTNATHAARACNGTNGARAARTGYAGYGCNYTNAAYGARCAR YTNYTNATHGGNGGNGTNGCNAGYCAYACNACNGAYMGNGCNGGNGGNTCNTAYGARMGN GARATGTCNGTNTCNAARGARGARTAYGARMGNYTNGARYTNMGNCAYCARGARGCNGTN AAYATGAAYCARAARTGGCARGTNTAYACNAARGARMGNGARAARCARTTYCAY------ ---GAYAARGTNCARGARYTNTCNGAYCCNCAYMGNYTNAAYGCNYTNATHGARGAYGCN ACNATGCARAARACNATGGAR---------------------YTNCAYCARAARGAYGCN GARATHATHGARYTNMGNAAYCARATHGCNGGNYTNTCNAARGARYTNACNGAYGCNMGN AAYTAYCARAARMGNATHCARCARGAYAGYAGYACNGTNGARATHYTNAARCARCARATH CARGTNTGYACNGARGAYTTYAAYACNGARMGNAARGAYMGNGARYTNGCNGTNCARAAR GCNMGNGCNYTNAARGARGAYGCNATHCARYTNAAYACNGARAAYGCNGGNYTNAARMGN CARATHGARYTNYTNAARAARACNATHGARCARCAR------------------------ ------------------------------------------------------------ ---------------------------------GAYGTNACNCARGTNAARGARTTYYTN GARTCNGTNAARYTNGCNTTYATHCAYAAYYTNAAYAARYTNAARMGNTTYYTNAARCAR GCNGARYTNGAYCAYTAYGCNYTNTAYAGYGCNYTNTCNTAYYTNAARAARTGYGGNTGY GGNACNYTNATHYTNMGNTAYGTNAARYTNGAYTCNGGNTCNGARACNAARTCNGTNYTN ATGGCNYTNGARAGYTTYATHAAYACNACNGARCARACNYTNCARAGYATHYTNTGYCAY TCNTGY---------CARTAYGCNACNTGYGCNGAYAARTAYGAYGTNAARAARTAYGCN GCN------AAYYTNGGNGARTGYGAYGAYGAYCARTAYTGYGTNAARTAYAARACNATH GTNTGGATHAARGAYTCNGGNGARATHAARGGNACNTCNMGNGARTCNCAYGTNGTNACN MGNAGYTGYGARTCNAARAARGGNCARAARGARGGNTGYATHGGNTGGCARAAYAAYGGN GGNGTNACNYTNAARTGYTGGTGYGGNACNGAYGGNTGYAAYAGYGGNYTNTCNYTNAAR GCNACNTCNGGNTCNYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CARAARCAYAGYATGYTNCARAGYCAR AAYACNGARATHGARGCNGAYTTYATGAARYTNAARCARGAYATGGARAAYYTNMGNGCN GARCAYYTNCARACNGARTCNCARCAYGCNCARGARTAYCARAGYYTNAARCARACNAAR GARAARGARATHGCNGAYYTNACNGAYCARGTNGCNGCNTCNAARAARCARAAYGAYGAY TAYCARGCNACNATHAAYCARYTNCARATHCARATHCARAAYTAYGARACNGCNAARCAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AARYTNATGGAYCARYTNGCN MGNAARAARTAYTCN---GGNCCNTCNTTYTCNGGNACNAGY------------------ AARGTNAARGGNTTYCAYTCNGCNAGYCARGARACNTAYGCNTGGAARYTNMGNAARYTN AARAARACNATHAARGARCAYATHTTYYTNAAYGGNGCNATHTGYGAYGARGTNYTNMGN ACNGARGARAARYTNGCNMGNGTNAARGARGARMGNMGNTTYYTNYTNMGNAARYTNYTN CARTAYCARTCNYTNACNGARTCNGCNGGNACNATHGGNAARGCNGAYACNCCNGCNGCN ATGGTNMGNAAYYTNAARAAYGCNGCNGCNGGNAAYGARCCNAGYTCNACNTCNGCNCCN TCNAARGGNTCNAARGGNGTNAARMGNAARYTNAAYGCNTCN---TCNGCNGCNCAYGCN GCNGTNGCNGGNGGNAGYGGNATHAAYATHGTNACNTCNYTNCCNACNYTNTCNTCNGGN ACNACNGCNAARAARAARCARCCNCARTCNGCNAARGAYATHYTNGAYTCNYTNCARGGN MGNCCNAARAARAGYAARTCNGCNGGNAARAARAGYATHCCNCCNYTNATGYTNGAYTCN YTNGGNMGNCCNATGATHCCNATGATGYTNGGNGARATHACNYTNCAYAGYATGGGNGAR ATHGTNATGGAYMGNCCNAGYTTYCAYTGYCCNGARGCNATHTTYCCNGCNGGNTAYTGY ATHACNMGNGTNTAYATHAGYYTNCAYAARCCNGAYGCNAARTGYYTNTAYACNTGYAAR ATHTCNGARGGNGAYAAYGARCCNYTNTTYGARATHGCNCCNGARGAYAGYTCNGAYATH GTNTTYMGNGCNAGYACNCCNTCNGARTGYCAYAGYYTNYTNYTNMGNGCNGTNAAYAAR TCNMGNGGNGCNGAYGTNGTNCCNACNGAYACNCARGGNYTNGAYTTYTTYGGNYTNTCN CAYTCNGTNATHCARAAYYTNATHCARTCNATHCCNGGNGCNMGNAARTGYTCNMGNTAY AARTGGGTNAARTTYGARATHGAYAARTCNGARTCNAAYGARAAYTTYGCNGTNGGNAAR AAYGAYCCNACNATHAGYTTYGARGCNTTYYTNAARCAYATHGCNGCNYTNACNCARTCN MGNCCNGGN---YTNGCNTCNCARATGGARAARTCNACNAAYYTNMGNTCNYTNYTNACN AAR---------ATGAAYTTYAAYGTNGARYTNGCNYTNGCNTCNGGNGGNMGNYTNGGN MGNATHGTNCARACNGTNCAYGGNMGNTCNATHGCNYTNGAYACNCCNNNNTGYACNYTN TTYACNNNNNNNGGNAGYGTNCCNTAYYTNAGYYTNAGYATGYTNAAYMGNGTNAARAAY GTNCCNGARYTNGCNACNATGAGYATHAAYTCNTTYGTNGARCAYGTNGAYAGYYTNACN GGNAGYGGNAARAARYTNGCNGARTTYACNTCNATGAARGARAARYTNGTNTTYTCNTCN YTNCAYGAYGCNAGYYTNCCNYTNCCNTCNGGNAARAAYGAYAARACNGGNGTNGCNGTN TGGGGNAARGGNGGNAARACNATGYTNGAYCCNGAYYTNTAYATGAARATHCARGARACN ATHCARCCNGAYTGGYTNYTNGCNYTNAGYGAYGGNGAYACNGAYMGNGAYAGYACNGAR AARMGNGCNGGNAARGCNGTNGAYMGNACNYTNGAYTTYYTNGAYAGYATHGTNTCNGCN MGNGARAARTCNGARGTNYTNAARAGYTCNAGYYTNATHGGNGCNGTNGTNGGNGGNTAY AGYGAYMGNCAYMGNCARMGNAGYGCNGTNGARACNTCNACNMGNCCNGTNCAYGGNTTY YTNYTNGARGGNTTYCARAARGGNAAYACNAGYGARAAYTCNYTNGAYGAYAARCCNTTY ATGGAYATHYTNTCNAARACNATHAGYCAYYTNCCNGARAGYAARCCNMGNYTNATGGAR ACNCCNTGGTCNCCNYTNGARGTNATHCARGCNGTNAAYYTNGGNATHGAYGTNTTYTCN AGYGCNTAYCCNCAYATHYTNGCNGARAARGGNCARGCNATGAGYGARGAYTTYAGYYTN TCNGARAARTCNTCNYTNAARACNGAYGARGTNACNGARMGNGARAARACNAGYGTNCCN TCNTCNGCNGTNATHGAYYTNAAYGAYMGNMGNTTYTTYGARGAYTTYAGYCCNATHYTN GARGGNTGYCARTGYTAYACNTGYGCNACNTTYACNMGNTCNTAYATHCAYCAYYTNYTN ATHACNTCNGARYTNYTNGCNCAYGTNYTNYTNACNATHCAYAAYTTYGARMGNTAYTTY YTNTTYTTYATHAARYTNMGNGARTCNATGMGNGAYGGNMGNYTNGCNGARYTNGARGAY AARATHAARCARCAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TTYTAYTCN ATHYTNAARTGGGAYTCNCCNYTNCCNTCNYTNATHTAYCAYACNGARGTNTGYGTNTTY YTNATHTGYYTNGTNATGTGYCCNGCNMGNTGGAAYTGYTTYGTNATHGCNAAYTGGTTY TTYYTNTGYCAYCCNCAYATGYTNAARAARTGYTAYAGYTAYGAYAARGTNAAYGCNGAY AARGARGGNGAYYTNGAYTTYGGNGAYGCNGAYGAYGAYAGYGTNGGNGAYGARGCNYTN ATHGGNYTNGAYCCNTCNCCNTCNAARCCNGGNATGGTNGCN------------------ ------------------------------YTNYTNTAY------GGNATH--------- ---------------------TTYATGACNCAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------CCNATHGCNCCNAARGTNAARGTNMGNYTNACNGTNACNCARTGG GARGAYACNTTYCAYTTYCARCARGARGCNAARGARCARAAYCAYYTNGAYGTNGTNTAY ATHTTYAAYMGNATGYTNGARGARCAYGCNTTYYTNTTYTGYTAYACNCARACNGARATG AGYGARACNACNYTNAAYACNGARMGNGARGAYAAYGARATHAAYYTNGCNGAYGAYATG AARGAYGARCARMGNGARATHGAYMGNYTNTTYGAYTAYGARTCNATGGARCARYTNTCN TAYYTNYTNGAYCAYTAYCAYCARATGAARGTNGGNATHTCNAGYTCNAARTCNAGYAAR CCNGAYAARTCNYTNGAYGTNGTNCARGGNTCNATGGTNGARGAYYTNGTNACNATGYTN CARACNTTYAARGARAGYTGYTCNAAYATHTAYAARCAYGGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGACNACNGTNTGYGGNTGGYTNAAYTTYTTYTGYYTNMGNGARGTNAAYAARAARAAR GCNGTNACNCAYMGNATHCAYCCNAAYMGNCARCAYTAYGAYGCNGTNGTNGTNTGGAAY GGN---AARGARAAYAARAARACNAARGGNAGYATHAGYTTYGAYGTNATHYTNAARCCN GCNGCNGCNGAYTCNCCNMGNCCNTCNYTNCCNGTNACNCCNMGNAAYAARATGCARAAR GARYTNTCNGARGARAARATHGCNATGAARYTNAARAARGCNGARCARMGNMGNAGYYTN ATHGARCARGARMGNATGGARCARYTNGCNAARGARMGNCARAARGCNATHGARGTNATH ACNAARGCNCARTCNGARAGYCARGARTTYTCNAARAARACNGARGARAARYTNMGNMGN TCNATGGARGTNMGNMGNGARAAYMGNGARACNCARATHMGNGCNYTNCARGARMGNYTN MGNGARCAYTCNGTNAARGTNCAYGAYGTNCARAARTCNGGNATGGARATGGTNAARGAR TTYGARGCNAARGCNGARAARAARYTNACNCARAARATGGGNACNTAYGARGARAAYMGN AARAAYCARYTNTGYAAYATGYTNTCNMGNYTNCARGARCAYGCNAAYCAYATHAAYGAR GTNTGYGTNGCNAGYGARAAYMGNGGNGCNAAYACNGAYGARYTNCARGARCARYTNGTN CARAARATGGARAAYGCNYTNAARAAYMGNGARGARCARYTNMGNCARATHCARGAYMGN YTNGCNGARCAYGARAAYMGNATHAARGARGTNCARAARAARAARGGNATGGTNTCNTCN GGNGARCCNACNGTNTAYAAYTGYCAYYTNTGYTCNGCNGTNYTNAGYTCNGARTTYTTY YTNMGNATHCAYYTNGCNAARCAYGGNGGNTTYAARCAYATHTCNACNYTNTCNTCNCAR GAYGGNYTNYTNATHTGYGCNTCNTGYAAYTAYATHGCNAARAGYAAYATHGAYYTNGTN AAYCAYGTNGCNACNCAYGCNACNGAYMGNMGNTAYAARTGYTCNYTNTGYGARTTYGAR AGYCAYMGNMGNAARCARGTNGARATHCAYATHGAYAARYTNCAYCARTGGGAR---TCN GGNMGNGTNATHGAYMGNGARMGNAARAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TTYYTNMGNYTNGARTCNCARGTNMGNGARATGGTNATHGARATHAAR ACNGGNYTNYTNCARAARYTNAAYGARAAYGGNGTNAAYAAYCCNGCNYTNGCNYTNGAY TTYACNAGYACNYTNYTNTAYCAYTAYGAYYTNATHACNAARAARGCNCAYYTNYTNGCN CARTAYYTNGGNGGNYTNACNGAYCAYYTNAARCARTTYCARGTNACNTGGGARYTNYTN AAYAARCAYYTNTTYCAYTCNATHGCNCAYAAYGAYCCNGCNATHAGYTGYGTNGGNCCN ACNATHYTNGARCARYTNMGNCARGGNTCNYTNCARTAYGARAARTCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARMGNMGNCAYCARCCNCARAGYGTNATHGAYYTNCCNCCNAAYATHMGNCAY CARTTYGGNAGYMGNGTNTGYGAYMGNYTNYTNTCNGAYCARGGNATHGTNACNYTNGCN YTNGARMGNCARAARTCNAARATGGCNCCNCCNMGNCCNTCNAARAARCARAAYGTNCAR GGNYTNCCNGTNAAYATGTCNAAYACNTAYGARAGYYTNGGNCAYACNACNMGNTAYAAY GTNTGYCCNGGNGTNAGYTCNGGNCAYAARATHAGYMGNACNAARGAYGARTTYAAYGAY GAYGTNCAYCARMGNMGNGTNCCNAAYCCNGAYGARTAYMGNTAYCARMGNGAYGARYTN AGYACN---TGGTCNGARCAYAAYGTNYTNMGNGARMGNATGAARAARGCNTGG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATHGCNATH ATHGGNAAYTCNTGYGTNATHTAYYTNGTNGTNTCNAARMGNMGNATGMGNAAYGTNACN AAYTAYTTYATHGCNAGYYTNGCNYTNAGYGAYATHATGATHGCNGTNATHTGYATHCCN TTYTCNTTYACNGCNAAYGTNYTNTTYACNTAYTGGCCNTAYGGNAGYTTYYTNTGYCCN ATHYTNAAYTAYTTYCARYTNGCNGTNGTNTTYCARAAYGCNTAYACNTTY--------- ------------------------------------------------------------ ---------CCNATGTCNACNAGYATHAARTTYAAYTGYAAYTGYTGYGAYTTYGTNGTN GAYTGYCAYTAYMGNGGNACNCARCCNCCNTTYGCNAARCAYATHGTNYTNCAYGARGAY TGYTTYGTNACNAARGAYCCNTTYTCNACNACNGGNGGNTTYATHTGYGTNGGNGCNTCN TGYTCNATHTGYAARGARAAYGTNTGYATGTCNAGYACNTGYAGYYTNTTYTAYACNCAR MGNTTYTGYGTNAARTGYGCNTAYGARAAYATHACNGAYTTYCCNTCNGARYTNCAY--- ------------------------------------------------------------ ------------------------------------YTNGGNTCNYTNGTNYTNYTNGCN GCNACNACNACNCCNGGNYTNGGNCARYTNAGYTGYGARGAYAGYGTNGARAAYMGNGAY TAYACN------TTYACNAAYATGGAYTGGACNGGNGCNGCNAARGAYTAYGCNTCNGCN YTNGGNAARTCNATHYTNTTYTAYGAYGCNCARMGNTCNGGNAARYTNCCNGCNAAYAAY CCNATHTCNTGGMGNGGNGAYTCNGCNYTNGGNGAYTGYGTNGTNGGNGGNTGGTAYGAY GCNGGNGAYCAYGTNAARTTYGGNYTNCCNATGGCNTCNTCNGCNCAYYTNYTNYTNTGG GGNGCNATHAARTTYAARGAYGGNTAYGTNAARGCNGGNCARATGGAYATGATGTAYGAY TCNATHAARTGGGCNACNGAYTAYTTYTCNAAYGCNTGGAAYGARGGNGCNCARGARYTN GTNGTNCARATHGGNGAYGGNAAYGCNGAYCAYGCNTAYTGGGGNMGNCCNGARGAYATG TCNATGTAYMGNCCNTGYYTNAARATHAAYAGYGGNACNCCNGGNAGYGAYATHGCNGGN GARACNGTNGCNGCNYTNGCNGCNGGNAGYATHYTNTTYAARGAYAARGAYGCNGGNTAY TCNACNAARYTNYTNAAYAARGCNAARAGYYTNTAYGCNTTYGCNAARGCNCAYMGNGGN GTNTTYCAYGGNAGYGCNCCNTTYTAYGGNTCNTCNGGNGAYAARGAYGARATGTGYAAY GGNGGNGTNTGGYTNTAYMGNGCNACNAARAAYAGYCARTAYYTNAAYGAYGCNAARGCN AAYGCNGAYYTNGGNACNGCNTGGGCNYTNAGYTGGGAYGAYAARMGNATHGCNTGYCAR ACNYTNYTNTAYGARGARACNAARGAYGGNTCNTAYAARGGNGCNATGGARGCNTTYTTY AAYTCNTGGYTNCCNGGNGGNGGNATGACNTAYACNCCNTGYGGNYTNGCNTGGMGNGAY AARTGGGGNGCNAAYMGNTAYGCNGGNAAYAGYGCNTTYGCNGCNYTNGTNGCNGCNGAR GAYGGNGTNATGTCNGAYMGNYTNMGNCCNTGGGCNGTNCARCARGTNAAYTAYYTNYTN GGNGAYAAYCAYCAYGAYGGNGGNTGYTTYAGYTAYGARATHGGNTAYGGNTCNAARTTY CCNMGNCAYCCNCAYCAYMGNGGNGCNTCNGTNAGYGGNCARATHYTNCARGGNGCNYTN GTNGGNGGNCCNGAYCARAAYGAYAAYTAYAAYGAYAGYCARGAYGAYTAYGTNATGAAY GARGTNGCNACNGAYTAYAAYTCNGGNTTYCARGGNGCNYTNGCNGGNATHGTNCAYYTN CARAARAAYCAYAARTTYCCNTCNACNACNAAYAARTGYCCNTGYTTYGARTTYTTYGAR GAYGARATHGARAGYYTNAARGAYTCNTTYCCNAAYCARACNCARMGNTTYTGGAGYACN YTNTCNGCNTCNGCNYTNCAYGTNTTYGARCARACNGAYCCNTGYTAYCCNAGYGTNATH YTNATGGCNTCNCAYAAYAARCAYCARCARYTNAGYTCNTGYYTNGCNAARAARATHGCN TAYGTNTTYTCNCARTCNTTYGAYMGNCAYTCNCARATHTCNACNACNGAYGTNGARGAY TTYAARCAYATGAAYGCNAAYGARCARAARYTNTAYYTNGAYGARGCNATGCARAARACN TTYCAYCARGARGGNGGNAARGCNTTYGTNATHAGYAAYATHCAYTCNYTNTCNCCNCAR GCNGCNYTNYTNYTNCAYGGNTTYTGYGAYGGNGAYAAYGCNCCNTTYAARGAYGTNATG ATHATHYTNACNTTYCARGTNGAYGARAGYGTNGTNTTYAARTCNGTN---------AAR CARGTNGARTCNYTNYTNACNGARATHTGGAGYAARGGNYTNGAYATGGAYAARYTNTTY GCNYTNATGAGYMGNGTNGCNAAYAAYCCNGTNGTNYTNATGGCNGARAAYGARAGYACN GTNAAYAARCAYTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GGNGCNGGNCCNTGYGTNTTYTGYGGNAAYYTNGTNTGYACNCCNGARGARATGGARATH YTNGAYMGNGGNACNAARAARTCNGARAARYTNMGNGARCARYTNATGAAR---TAYTCN AARTCNAARGGNYTNAGYGARACNGCNCARTCNATHYTNCCNATHGGNTTYAAR---AGY CARCAYAARGARGARGARGARAARGCNYTNAARCAYMGNGAYAARYTNYTNGARTAYGAY MGNACNAGYGTNMGNMGNACNCARGTNATHGAYGAYGARTGYGAYTAYTAYGCNACNGAY TCNAAYMGNTGGYTNAARAARGARGAYMGNGARAARYTNMGNAAYMGNGARGARGARYTN MGNGARTCNMGNTAYGGNTCNMGNMGNAAYMGNAARATHACNTTYGAYATHGCNGGNMGN GAYGTNMGNATHYTNGAYGCNGARGAYGAYTCNGGNAARAAYATGTAYAAYMGNGARGAY GCNGTNATHCARGARGTNCAYTAYGGNAARTCNYTNCCNAAYGGNTTYGGNAAYGCNGAY YTNGTNAAYCCNGCNTTYGAYTTYGARCCNCCNACNTTYATGGAYACNCARCCNGTNCAR TGGGGNCCNGAYTCNTTYAARACNGCNTCNGTNGAYAAYTTYAAYCARCARACNTCNTCN MGNMGNATHCARGAYAARGARYTNCARGARATGAGYGAYGARGGNATGTGYYTNAGYATG CAYCARCCNTGGGCNTCNYTNYTNATHTGYGGNATHAARATGCAYGARGGNMGNACNTGG TAYTCNTCNCAYMGNGGNMGNYTNTGGATHGCNGCNACNGCNAARCARTGYGAYCARGAR GARGTNMGNGAYYTNGARCARTTYTAYAARCAYTTYTAYTCNGAYTCNACNATHAARTTY CCNAARGARTAYCCNACNGGNTGYYTNYTNGGNTGYATHAAYGTNGAYGAYTGYYTNGAY CARGGNCARTAYMGNGARAARTAYCCNGARGGNGARTCNMGNTCNCCNTAYGTNTTYGTN TGYTCNAAYCCNTCNAARYTNATHGTNAARTTYCCNATGAARGGNMGNCAYAARATHTAY AARYTNGAYTCNCARATHCAYCARGCNGCNMGNAARGGNATHMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TCNGAYGCNGTNACNGGN ATHTTYTCNYTNGCNTTYYTNYTNACNYTNATGACNTTYATHYTNTCNGTNYTNGCNGTN ACNTGGTGYTCNYTNTCNTAYYTNACNGTNAARCARGARATHAAYACNTCNMGNYTNTCN AGYATHYTNAGYYTNTTYMGNTGGTCNMGNYTNCCNYTNYTNGTNATHTGYYTNACNAAY GGNTCNATGTGYGCNTGGAGYTTYGCNMGNTTYACNGGN---GTNACNTTYACNGAYTTY ATHAGYACNCARGARTAYGARAARACNGTNYTNAAYGARMGNTGYYTNTTYATHATHGGN TGYGGNATGTTYTCNGGNTTYAGYTAYTAYTGYCARTTYTTYACNCARCAYAARTTYCAY YTNGGNTTYCCNGGNATHCARMGNCARAARGTNTTYCARGTNMGNAGYGARACNAARGCN ATGGCNGARAARATHTGYTGGMGNACNYTNCAYGTNATHAARTAYTAYTAYATHYTNTAY TTYYTNTTYGGNTCNYTNCCNMGNTCNTGGATHTGYACNTCNTTYGGNATHAGYGARGAY ACNGARATHTCNCCNYTNGAYTCNYTNATHGGNYTNATGAAYYTNTCNYTNYTNTGGAAY TCNTAYYTNACNTCNTTYGTNYTNACNTTYGCNYTNTCNTTYACNYTNGCNYTNACNMGN ATHTTYCAYACNGARCARYTNGARTTYCCNATHACNACNATGATGGARTAYACNACNGAR MGNACNYTNTCNGAYGCNYTNGTNTGYTCNTAYTCNCCNYTNYTNCARCAYYTNGCNTTY TTYGAYYTNGCNTGYYTNAGYAARTTYGTNTCNCCNMGNYTNCARGARYTNYTNAGYYTN AGYCARCCNGGNGGNCAYCCNAARGTNTGGATGTCNGTNAGYCARTCNGCNYTNTCNGCN ATHCARGARYTNACNAAYCARGTNAARGARGARAAYTGGTCNATHATGTCNAARGTNCCN ATHAGYCAYCAYCARAGYATHGCNAAYGGNAAYGGNACNGGNGCNCAYAGYYTNAAYAGY GGNGARMGNYTNGAYTCNACNGTNACNTAYMGNGGNGAYGGNAARCAYGAYYTNGTNCAR ACNGTNMGNGAYGAYCCNGARATHTCNCARYTNAGYACNMGNYTNTCNTCNATHCCNGTN YTNTCNCAYYTNGTNACNCARAGYCARGAYTCNACNAGYMGNCARYTNTTYGTNTCNTGY CARAARCARATHTGGGCNGTNGARAGYYTNTCNCAYATHGCNGTNMGNGCNTAYACNGAR GAYAARTAYGGNATHGTNCARACNTCNYTNCCNATHATHTTYATGTCNYTNYTNGARYTN CAYGARTCNATHGARAARCAYTTYAARYTNAGYACNTCNCCNMGNMGNTCNAAYGGNTCN GTNCARCCNTCNCCNGAYACNGCNATHMGNTAYAARYTNCARTCNGTNYTNAARTCNTCN YTNTAYMGNATGGTNAAYACNTAYMGNTCNCAYYTNGARGAYATHAARYTNMGNCCNGAR GARATHAARAARYTNACNCCNTTYTTYCARTAYACNYTNTTYAARGCNATHCCNTAYACN TTYTAYGARGTNGGNTCNACNTAYTTYTGGGTNCAYTTYGGNYTNGTNATHYTNGGNTTY GTNYTNGCNGTNGTNACNTGYATHGCNCARTGGMGNAARCCNGCNCCNTAYGGNAARCAY GAYTCNAAYGARGARAAYTGGGGNCCNYTNATHCCNCARMGNYTNTCNCAYTTYATHTCN GAYGCNYTNTCNGGNGTNYTNATGTTYTCNYTNGTNTTYTTYYTNTAYAGYAARGARGAR AGYGAYAARAARGCNYTNAAYTAYGTNTTYTTYGGNYTNTTYYTNGTNCAYACNGTNCAY MGNGGNATHATHCAYCCNYTNATHATGMGNTAYAARAGYGCNAARGTNTCNYTNGGNATH TGYATHGGNGGNGGNYTNCCNAAYGTNYTNTAYCARTGGYTNATHGCNAAYCAYATHGGN GTNGCNAARTAYGAYGAYTCNTAYCCNTAYGAYCCNMGNTTYATHYTNGGNGTNGTNYTN TAYGTNGTNGGNTTYGTNATHAAYMGNTGGGCNGAYTGGAARYTNMGNTCNYTNMGNAAR AARAARGGN------------------AGYAARGGNTAYTAYATHCCNTTYGGNGGNYTN TTYAAYTAYGTNTCNTGYCCNAAYTAYTTYGGNGARYTNGTNCARTGGACNGGNTGGGCN ATHGCNACNTGGTCNYTNTCNGGNTTYGTNTGGGCNTGYTTYGGNGCNGCNACNTTYYTN GCNMGNTCNMGNCAYAAYCAYAARTGGTAYCARGAYCAYTTYGAYGARTAYCCNYTNAGY MGNAARGCNYTNATHCCNTTYATHTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AGYTAYCAYAARCARGGNCARGGNMGNATH GARAARACNGARATHATHGARATGGCNATHAARCAYATHAAYATGYTNCARCARMGNGTN GARGARYTNGARAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNAARTGGTGGATGGTNGCNTTYGGNTGGACNYTNTCN ACNGTNACNGCNYTNGCNYTNGTNTAYGGNGTNTAYGGNGAYACNTCNGGNAAYCAYGTN AGYAGYAAYGGNGTNTCNGCNYTNTAYAAYGCNGTNTCNMGNTCNATGTGGGGNYTNGTN ATHGCNTGGATHATHYTNGCNTGYGAYTCNGGNTAYGGNGGNCCNATHAAYGCNYTNYTN TCNTGGCARCCNTTYGTNGTNYTNGGNMGNYTNACNTTYATGACNTAYYTNATHCAYYTN TAYATGGTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TTYAARGAYATHGGNACNATHCARTCNGTNMGNGTNGARCAYGAYGGNMGNGGNGTN GCNGCNGGNTGGTTYYTNGAYMGNATHATHYTNCARAGYGTNGARMGNGCNAAYATHATH TAYTAYTTYYTNYTNAAYGGNTGGYTNGCNMGNGAYATHGGNGAYGGNCAYYTNTGGMGN GAYATHCCNGCNAARMGNAARYTNGCNAARGARGTNACNTCNGGNAARCCNGTNAAYTAY CARGTNTCNGTNACNACNGGNGAYGTNMGNTAYGCNGGNACNGAYGCNAAYGTNTAYATH ATHATHCARGGNAARAARGGNACNACNAARAARATGTTYATGGAYGAYAGYMGNGAYAAY TTYGARMGNGGNAARACNGARGTNTTYGARYTNAAYGCNYTNGAYGTNGGNCCNATHACN CARATHCAYATHGGNCAYGAYAAYTCNGGNCCNGGNGCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNTTYGGNAARTGYAARMGNGGNAAYAGYTGYATGTAYATHCAYGAYCCNGAYAAR ATHGCNGTNTGYACNMGNTTYYTNMGNGGNACNTGYCARGAYGARGARTGYGCNTTYTCN CAYAARATHGAYCCNAAYAARATGCCNATGTGYTCNTAYTTYYTNYTNGGNAARTGYTCN MGNGAYGAYTGYCCNTAYMGNCAYGTNAAYGTNAGYMGNTCNGCNCCNGTNTGYGARGAY TTYYTNAGYGGNTAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AGYGGNGTNCAYYTNACNGAYGARMGNATHGAYGARATHYTNMGNGTN GCNAARGARTGGTGYYTNTCNAAYGGNGTNGGNATHAARTGYGGNTAYAAYGARCCNGAR TCNTCNAARGTNTGYTGYGCNCCNATHGCNYTNTTYCCNAGYYTNGTNCCNTCNCCNATH YTNACNACNGCNAARTCNACNATGCCNCAYTTYAAYMGNYTNATGCAYAARGTNGCNATG GAYCAYCARTTYYTNGARGAYTCNYTNAARAAYGTNGTNCARGTNGAYGARTTYATGYTN AAYYTNTGGAAYATHTAYACNMGNGTNMGNGARAAYGGNATHAARCARCCNATHATGYTN GGNYTNTTYMGNAAYGAYTTYATGATHAAYTGYAAYAAYCARGARGARACNAGYGARAAR TAYAAYGCNGARAAYYTNCARATHAARCARATHGARTTYAAYACNATHGCNTCNAGYTTY GCNGGNYTNACNCARAARYTNGGNGAYYTNCAYMGNYTNACNYTNGGNATGGCNGGNAAR CARTTYACNMGNGAYCARACNCCNACNAAYYTNCCNGTNTCNGGNYTNGCNTCNGGNYTN GCNMGNGGNTGGGARYTNTAYAAYAAYCCNAARGCNATHATHGTNTTYATHGTNAGYGAY TTYGARMGNAAYGTNYTNGAYCARTGYGCNYTNGARTTYGGNGTNTAYAARMGNAAYCCN CARATHMGNGTNYTNCAYAARACNATHYTNGARATHGARGARMGNGGNAGYYTNGAYGAR GARGGNMGNYTNATHGTNGAYGGNGAYGARGTNGCNGTNYTNTAYYTNMGNGAYGGNTAY ACNGTNGAYAAYTAYCCNTCNCARAARGTNTGGGAYGGNMGNYTNAARATGGARYTNTCN MGNGCNATHAARTGYCCNTCNATHCARTAYCARYTNGCNGGNGCNAARAARATHCARCAR GARYTNGCNMGNCCNGGNGCNYTNGARMGNTTYATHGAYGAYGCNAAYGTNATHAARAAY YTNMGNGCNACNTTYGCNGAYCARTAYAGYYTNGAYYTNGGNCCNGARGGNGAYAARGCN ATGACNYTNGCNATHGCNTCNCCNGAYAARTTYGTNYTNAARCCNCARMGNGARGGNGGN GGNCAYAAYYTNTAYGGNGARAAYATHATHCARTTYYTNACNAARCAYAARGAYAGYAAR GARMGNAAYGCNTAYATHYTNATGGARMGNATHTTYCCNYTNCARCARCARAAYTAYYTN TTYAARGARGGNGTNCCNTTYTGYYTNTCNACNGTNGTNAGYGARYTNGGNATHTAYGGN YTNTAYATHGGNACNGARAAR---GARGARATGGTNAAYCARGARTGYGGNCAYATGATG MGNACNAARATHTCNGGNACNGAYGARGGNGGNATHGTNGCNGGNTTYGCNGTNYTNGAY ACNCCNYTNGTNATH--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGGCNGARAARTAYACNGCNYTNYTNAAYAAYGTNGTNTGYTAYAGY GCNGCNTCNTTYTGYTTYTCNYTNGCNAARGARACNGGNACNTTYAAYACNYTNYTNGCN GCNAGYAARCCNYTNACNTCNGARGARATHGCNTCNGARAAYAARATHAARGARMGNTAY GTNMGNGARATGYTNGGNTGYYTNACNGCNATHGARATGGCNAARGTNTCNCARAAYGAR GAYGGNGTNAAYGTNTAYTAYYTNGARGARGCNGCNAARAARGCNYTNAAYGGNYTNGGN GTNTCNYTNGCNGARATHAAYTTYACNCCNGCNYTNGCNTCNTAYGARGCNGTNAARGAY TGYGTNGGNGCNGAYAARTCNGGNGCNTGYMGNTAYCARCARTCNTTYATHAAYTGYYTN GAYGAYTAYAARGCNAARYTNACNGAYGTNACNGTNAAYTTYYTNYTNAARAAYATHCCN GGNGTNAARGARAAYYTNGARAAYGGNATHGAYGTNATHGARTTYGGNTGYGGNAAYGCN TAYCAYYTNTCNGTNYTNGCNACNATGTTYCCNAARAGYMGNTTYGTNGCNTCNGAYGTN AAYCCNGARTTYYTNGARCCNYTNAARAARMGNTAYAGYCAYATHCCNAAYYTNGAYTAY GGNGTNGTNGAYYTNTGYGCNGTNCCNGAYTCNGTNGAYAARAARTAYGAYYTNATHTAY GTNAAYGAYGTNATHCAYGAYYTNCCNCAYCCNGCNGARTGYYTNAARGGNGTNAARMGN ATGATGAARGARAGYGGNAGYTAYTGYGCNATHATHGAYTTYGCNGGNACNGGNAGYCAY CAYAARGAYGCNGGNGAYYTNTAYGCNGTNTTYAARTAYGCNGCNTCNACNTTYYTNTGY ATHCCNGARAGYTAYCARATHGCNGAYAGYGARGCNCAYGGNGCNGCNGTNGGNAARGAY ACNATGGTNGGNTTYATGAARACNGCNGGNTTYGAYGTNCARTTYCAYCCNATGGGNGAR CARGCNGGNYTNTAYYTNTGYAAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNAARAGYYTNTTYACNGGNTTYATGGCNTCNNNNGGNNNNNNN ATHNNNATHGCNNNNNNNACNGCNATHCCNATHTCNATGATHNNNATGGGNGCNNNNTAY AARGAYGAYTGYCCNGCNGARGAYATGATHNNNATHTAYYTNATHGTNATGGGNGCNGTN NNNNNNNNNMGNAAYNNNATHNNNATHNNNATGNNNNNNNNNMGN---------GAYGGN GAYNNNGAYNNNNNNNNNGTNAAYCCNTGYACNTGYATHYTNGAYGTNTTYYTNNNNGCN TGGTTYATHGCNGGNTGYGTNNNNATHTAYMGNACN---AARGAYGANTTYCARTCNNNN GAYTCNNNNGCNGAYGAYTTYTGYAAYTAYACNYTNTAYTGGTAYNNNTTYTGGGTNACN ACNNNNAGYTTYATHYTNNNNGGNNNNATHYTNGTNGTNNNNNNNNNNNNNGGNTGYNNN GCNNNNTGYTGYGCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CARGTNGCNAAYAARGAYTTYYTNCAYGAYYTNATHAARATHATH GGNCCNAARAAYGAYCCNCCNCARATHATHCARGARAARGTNYTNGCNATGATHCARACN TGGGCNGAYGCNTTYMGNGGNAAYCCNGARYTNAARGARATGGARAARGTNTAYCARGAR YTNAARCARAARGGNATHGARTTYCCNATGACNGAYYTNGAYAAYATGGCNCCNATHCAY ACNCCNGCNMGNAGYGTNCCNGAYMGNGARCARCCNACNYTNAGYCAYGAYMGNGGNGGN AGYAGYMGNGGN------GCNCCNGCNGCNATHCCNCARACNACNGGNACNCCN------ TAYCCNATGGTNCAYCCNATGGGNGAYGGNAGYMGNTCNGGNCCNYTNAAYGGNGAYCAR YTNTCNAARYTNMGNMGNGARYTNGARGTNGTNCARGGNAAYGTNMGNATHATGGGNGAR ATGYTNACNGARYTNAGYCCNACNAAYGTNGAYTCNTCNGAYYTNGARYTNYTNCARGAR YTNAAYMGNACNTGYMGNCARATGCARTCNMGNATHGTNGARYTNYTNAAYGARACNGCN GCNGARGARGTNACNGAYGAYYTNYTNMGNGTNAAYGAYGAYYTNAAYAAYGTNTTYYTN MGNTAYGARMGNTTYGARMGNTAYMGNACNGGNCARTCNGGNCARGCNACNACNCCNTCN TCNGARGTNCCNCCNCCNGAYTCNYTNCCNCCNGCNTAYGAYCARYTNCCNGCNGCNAGY AAYCCNAARGTNGGNAAYYTNATHGAYYTNAGYGAYGAYCCNACNCCNGCNGAYAAYTCN ATHAAYTCNCARYTNGCNGGNYTNACNYTNAGYTCNACNACNGCNACNAAYGCNGGNCCN CCNCCNCCNGCNMGNGGNGAYGAYGAYTTYGAYATGTTYGCNCARTCNMGNCARTCNTTY GAYCARAGYMGNCARGCNGTNCARTCNAGYGCNTAYAAYAAYCARCAYCCNGAYACNTTY AGYGGNGGNYTNGGNCARGCNGTNAGYGCNMGNTCNAAYGARGARACNATGAARYTNCAR GARAARGAYTCNGAYTAYGAYGARATGGARCARTGGYTNGCNACNCAYGAYAGYCARCAR TCNGAYGTNAAYTCNCARGARCCNATHACNAGYTCNGARTTYGAYMGNTTYYTNACNGAR MGNGCNAGYGCNTCNGAYTCNGTNCCNAGYATHCCNGCNCARACNGGNMGNTCNACNMGN ACNYTNCARAARAARGAYGAYGAYGARAAYCCNYTNTTYGCNYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------YTNMGNGGNGAYCCN YTNGGNGAYYTNAGYATHTCNGCNCARGGNATHATHMGNMGNGAYGARATHGTNTTYGAR GCNGCNMGNACNMGNCCNATHCCNATHACNATGGTNACNTCNGGNGGNTAYCARMGNTGY ACNGCNGARGTNATHGCNGAYTCNATHCAYAAYYTNGTNMGNAARGGNATHATH------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GTNCCNGTNATHAAYGGNATGTCNGAYYTNYTNCAYCCNYTNCARATH YTNGCNYTNTTYATGACNATHCARGARTAYTTYGGNTAYYTNMGNGGNAGYCARGTNTGY TGGATHGGNGAYTCNAAYGGNGTNYTNCAYTCNYTNATGCAYGGNTGYGCNMGNYTNGGN ATHGAYYTNAAYATHGCNACNCCNGTNGGNTAYGARCCNAAYGCNGAYATHACNATGGAY GCNATHAARATHGCNGGNCARACNGGNGCNTCNYTNCARATGAGYAAYAAYCCNGTNGAR GCNGCNTAYMGNGCNAAYGTNATHATHACNGAYTCNTGGTAYMGNTCNGGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGTCNGARGGNTCNGCNTCNCCNAARMGNCCNMGNYTNGAY TTYGAYGAYAGYTCNAARGAYGAYATHCAYGAYAARYTNAGYAARAAYMGNGAYCAYGAY GAYCARGGNAGYTAYAGYACNTCNMGNAARMGNMGNGCNGAYACNGGNGAYGAYGAYGAY GAYGTNAARGAYTGYGAYGAYYTNAARTCNAARACNGCN---GTNGAYGCNGGNMGNMGN GARCAYACNYTNGTNATGMGNYTNACNAAYAARGARCARGARGTNCARGARTGYATGAAY CARATHCARGARATGAARCAR---------------------------------CARYTN GAYCCNGCNATHAAYYTN------------GTNTTYCARMGNATG--------------- ---------------------------------------------------TCNAARGAR ATGGARGARCAYAARGARAARYTNAARCARAARCARAAYGARYTNAAYGCNTGGAARTTY ACNCCNGAYAGYCARACNGGNATGMGNYTNATGGGNAARTGYMGNATGYTNYTNCARGAR AAYGGNGARYTNGGNAARATGATHTCNTCNGGNMGNACNGCNMGNYTNGARGGNGARATH TCNYTNCAYAARGCNYTNGTNGCNGARATGAARAARAAYCARAARGARYTNGAYGARTTY GTNGGNGARYTNGARGARGAYGTNGARGGNATGCARGGNATGATHTTYATGYTNCARCAR CARYTNAARGARGCNMGNGARCARATHACNMGNYTNCARCARGARAAYGARCARYTNMGN ACNYTNCARYTNCCNTCNGARCCNGARCCNGGNGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY AAYGAYMGNAAYACNTGYGARGCNCCNGARGTNAARTAYGAYGARAGYGARCAYATHYTN ACNAARTTYACNCCNGGNTCNATHGTNTGGGCNAARATGGAYGGNTTYCCNTGGTGGCCN GCNATGATHGAYGTNGAYCCNGAYTAYGAYACNTAYTTYGARYTNCCNTCNGCNGCNAGY ATGATGCCNTAYATGTAYCAYGTNACNTTYATGGAYGAYCAYGTNTCNMGNGCNTGGGTN AARTCNTAYYTNGTNACNCCNTAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNMGNTCNAAYYTNGTNGGNACNAARTTYACNTGYTTY GAYAGYGGNCARAGYCCNAARAARGGNGGNGGNTCNAAYYTNMGNGARGARYTNTGYGCN GTNGTNTAYGAYACNAAYGTNYTNGGNTTYAARGGNCCNMGNAARATGACNGTNATHATH CCNGGNATGGAYGTNAAYCAYCARMGNGTNCAYGTNAARCCNCARAAYGARATHGARACN YTNYTNGARMGNCAYMGNACNAARMGNATGCARAAYYTNATHACNYTNCARAAYAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG GCNTCNTCNAAYAARTGGGARGTNGTNTCNAARAAYAARAARAAYACNGGNGARCCNCAR AARYTNTCNCCNAARMGNMGNAAYGARYTNATHGARAAYATGCCNMGNYTNGARACNAAR GAYCCNATHGARYTNGAYACNACNYTNTAYTCNGCNTTYYTNCCNAARGARCARGCNCCN GTNGGNAAY------TCNAARGARGARGCNAAYAARCARAAYGGNGCNAARAARAAYTCN AGYCARAARAARAAYAARAARGAY---------GARAARAARGCNAARCCNGTNGAYATH GAYGTNGCNYTNTCNCARYTNGAYCCNAAYGARYTNAARATGGTNYTNGARAARACNCAR TCNATGTTYCCNAAYCAYCARATHATHTGGYTNAARGAYYTNGTNTCNTTYYTNAAYAAY AARYTNGARATHGCNAARGAYTTYGAYCCNGTNTAYAGYGAYAARTCNTCNGGNTTYCCN TTYGAYGCNGTNCCNTCNGCNGTNGCNAARGAYYTNMGNACNTTYATGAARCARTTYTCN AARGARACNYTNGAYAAYATHTTYTTYTAYGCNATHAARACNATGTGYCARGARATHGGN MGNGGNAAYCCNGTNCAYGGNTTYAARGTNTTYYTNCARYTNATHATHAAYATHAARTCN GAYACNGGNYTNGAYCARYTNCCNCARTAYATGGARATGYTNAARYTNCAYCARCAYAGY CCNGGNAARTGYYTNTCNATHATGTGGGCNYTNGGNCARTGYGGNAAYAARCAYTTYCAY TTYGGNYTNAARGTNTGGYTNGARYTNATGYTNCCNGCNYTNGARATHAARCARATHGCN CAYTAYCCNGTNGARTAYYTNGARAAYYTN---------TTYAARAARTAYTGY---AAY YTNCCNAARAARAGYTAYGARYTNATHTCNYTNMGNGARTAYTTYCARGTNYTNGAYGTN TTYTTYAGYCCNAARTTYCCNYTNATHAGYGARYTNAARTAYMGNYTNATHCARGTNTAY CCNACNYTNAARACNYTNGCNTTYGGNGARGARCCNTCNCARACNYTNMGNACNTTYTTY CCNTCNTAYYTNACNMGNTTYGCNAAYGCNMGNACNAARGARATGAARGARGARYTNYTN GTNTGYATGACNGARTGYYTNACNACNGAYAARCARTCNTTYGGNGTNTGGTGYCARYTN TAYACNAARCAYYTNGTNACNTCNAGYMGNYTNYTNGAYTAYATHAAYACNAAYTGGCAR CARYTNTCNTCNMGNTTYGAYAARAARATHYTNAARGARACNYTNMGNTCNTTYTCNGTN ACNAAYGARGARYTNGARGTNCARACNAARGGNACNCARGAYGGNYTNAARYTNAGYCAR GCNGCNACNAARGAYYTNATGGCNAARATHAGYGCNGCNCAYTTYCCNTGGAGYYTNTTY GTNTTYATHYTNATHTCNATHTTYGCNGGNATHGTNATHTAYGAYGTNACNTCNAGYCCN ACNCCNCARTCNTCNAARAGYATGCARTTYYTNGARCAYTAYGGNATHYTNACNYTNYTN GARAARGCNTAYCAYAAYGTNCAYCAYTTYACNACNYTNTCNGTNAAYTGGGTNAARGTN AAYTTYCCNATHTTYTAYAAYCARGTNMGNGARACNGTNGTNCCNTTYYTNGTNATGGCN TGGAAYACNTCNAARGAYTTYYTNATHAAYGCNGARGTNCAYTCNMGNCCNTAYMGNGCN YTNGCNYTNGARAARYTNATHCARTTYTAYCAYTGGGTNTAYGARYTNTCNCCNGARTTY TGGATHMGNTGYGARGARYTNYTNTGGYTNTCNTGGGAYYTNTGYAARGAYTAYTCNTTY MGNATHTGGATGCAYGCNCARCARTTYCCNGGNGARGCNAAYCAYTGGYTNACNGARCAY GTNYTNACNGGNTCNTTYTCNAARGARGCNATHAARGAYACNGCNYTNTGGGGNGTNGAR CAYYTNCARAAYTGYACNACNYTNYTNGTNACNTGG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AGYATHGAYACNGGNGCNTCNTTYACNCARCAY YTNAARGARACNGARAAYMGNYTNAARGARTTYGGNAGYTTYATHTCNAGYGTNGCNAGY CAYGARCCNATHAAYGARATHTTYGARCARATHAARCAYATHGAYAAYGARATHGAYATH AARYTNAARAAYYTNGARAGYGCNATGTCNAAYAAYCARAARGCNGTNCAYGARYTNGAR GCNGARAARGARGARYTNTCNMGNMGNATHAGYYTNCAYAARATHAAYTTYAAYYTNTCN CARGAYGARTAYAAYCAYYTNYTNAARGARMGNACNYTNATGAARAAYGTNCCNGAYAAY GARATHAAR---GARYTNAARATHAARCARYTNGARGCNGARGAYYTNATGTTYMGNAAR CAYYTNGGNATGGARATHMGNAARATGAARGGNGGNTGYYTNCARGTNGCNTTYAGYCAR ATHGAYCARAAYCARCCNAGYTCNYTNTTYYTNTTYTCNYTNAARYTNGAYGARAAYMGN CARTAYATHATHACNGAYTGYAARCCNCCNATHGCNGAYYTNGAYGAYATHGTNCAYAAR YTNAAYAAYGAYAAYGAYTTYMGNAAYTTYATHMGNACNATGMGNMGNAARTTY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNAARMGNMGNTAYAGYGAYGTNYTNGAR---GAYYTNTAYMGNGGNCCNCARGAY TTYATGGARGCNGGNGCNMGNGGNTTYYTNATHACNTCNATHCCNGAYMGNGARGARCAY TCNATHGAYGARACNGTNAARGTNYTNMGNAARACNTGYGTNAARYTNTAYGGNGGNATH AARCCNYTNAARMGNGARGAYGCNTCNTTYGCNAARGGNTAYGTNATGGTNGAYTTYATG GAYCCNGARACNGTNATHAAYATHCCNAAYCCNGAYGCNGARAARGCNGCNGARGARGAR GARAARGCNAARGCNGCNACNGARGARACNGARGARGCNACNAARGARGARACNAARGAR ACN--------------------------------------------------------- GARGARATGGARGARGARAAYAARACNGARCARGARGARGAR------------GTNAAR CCNGARGGNGGNGAYGCNATHGARGARAARGARAARACNGTNGGNGARGGNGARGCNGCN GCNCCNGARACNAARGAYACNAARCCNAARGARGAR------------------------ ------------------------------AARAARAARAARGARGAYACNMGNMGNMGN MGNGAYGARGAYAARAARCCNYTNATGYTNGCNCCNTAYAARTTYAAYGCNTAYMGNACN GARYTNMGNAAYATHATGTTYATHAARTCNGAYATHCCNGAYCCNGTNGARGTNGTNAAY GCNTGYTTYGAYATGATGYTNAAYMGNAARCCNYTNTAYACNGAYTGYGTNAAYCARYTN YTNCCNGTNCARGGNGTNTGYAAYAAYGAYTAYAARCARYTNGARATHATGTGYMGNMGN GTNYTNGTNCCNTAYTTYGGNGARCAYYTNGARGARCCNCCNAGYTTYGGNGTNATGYTN ATHAAYAARATGTGYGARCCNGGNGCNGARGTNYTNYTNGAYGTNGTNMGNAGYGCNATH TGGTGYYTNAAYCCNYTNGCNTGGCARAGYTCNCCNTGGGCNGARCCNGAYGTNGTNGTN CAYGTNGARYTNATHGGNAGYAARATHGTNATHAGYGCNATGCCNCAYTAYATGAARTAY MGNCARTAYAGYCCNTTYGTNGTNCAYGARYTNGGNGCNGGNAARCCNGARGAYGAR--- ---GTNCARYTNYTNAARGARATGAARGARGARAAYTCNMGNGAYMGNGARMGNGGNGGN MGNGGNGGNAARGGNMGNGAYMGNMGNGGNCAYMGNGAYMGNGARGAYMGNAARCAYTCN GARAARGARCAYGARAARAARMGNGGNNNNGARGARGCNAGYAARGAYACNGARAAYACN CARAGYGCNGAYAARGARAAYACNGTNAAYTCNGARAARGARCAYACNGARGARGCNAAR GARGARGARCCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ACNTAYAARGARTAYGARAARAGYMGNCAR ATGCARAARYTNYTNTAYAARAARGGNGCNAARACNMGNAARCAYTGGTAYAARTCNCAY YTNGGNGARGCNYTNGARGTNGCNACNAARAARACNAARMGNACNGTNTCNCAYAGYCAY AAYATHMGNYTNMGNCARYTNAGYCAYGTNYTNTAYGAYAARGTNATHGAYATHATHAAY ACNGGNGARYTNTCNCARGARGTNYTNGAYAARCARGTNTCNATHACNGCNGTNAARGTN GCNAARGAYGTNAAYAGYGTNAGYGTNTAYTGGGARGCNGAYMGNAAYGAYTGGAARGAY GTNGARGAYYTNYTNGTNGCNCAYAGYGGNAARYTNMGNAGYYTNYTNATHTCNTAYCAY GTNYTNGGNMGNATHCCNCAYGTNGTNTTYGTNAARGAYGARTCN---GCNACNAAYYTN CAYCARYTNACNGARYTNTTYCARAARGCNGAYTAYGGNCCNGAYTAYGTNCCNGGNGTN AAYAAYACNGARGCNGARGTNGTNAAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------MGNAGYYTNAARGAYTTYTTY MGNGCNTCNCARACNGCNATHGAYTCNGAYMGNGAYAAYAGYACNTGYGARMGNMGNCCN YTNNNNATHGGNTTYAARGAYYTNGGNTGGGCNGAYTGGATHATHGCNCCNGAYGGNTAY AARGCNGCNTAYTGYGGNGGNGARTGYNNNTTYCCNYTNNNNCCNCANATGAARGCNNNN AAYCAYGCNATHATHCAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARAARGCNACNGGNTTYMGNCCNCCNCARGARCCNAARTCNTCNATHYTN TCNTCNATHYTNAAYGCNATHATHACNAARGGNGCNAARCCNATGGCNAARYTNCCNTGY GGNMGNAARAAYCAYATHACNGCNGCNAAYAARTCNTGYATHYTNGTNCAYGGNGGNGAR ACNTTYGAYGGNMGNAGYMGNGARCCNGTNGGNGARATGTTYYTNATHTCNYTNGCNTCN CCNACNATHTTYTAYAARYTNAAYACNACNAGYATHMGNMGNGCNGGNCAYGTNTGYTGY GTNTCNGARGGNGGNATHTAYATHCAYGGNGGNTTYACNGGNCARTCNAARATHAAYTGY GAYYTNTAYCARYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHMGN TCNACNGCNGARCAYCAYACNGCNCAYATHGCNCARTAYCCNCCNCAYTCNCCNAARYTN GTNAARGAY---TCNTTYACNTCNCARTCNAAYMGNMGNGTNGAYTCNGCNMGNMGNATH MGNGGNTCNATGGARAGYYTNCCNYTNAAYAARMGNTCNCCNMGNGAYGARGCNTTYCAR GARGTNAARGARTTYCAYATGGAYGCNGARGAYTGYYTNMGNAAYYTNGARGAYAARATH TCNGCNYTNTCNCCNTCNGGNGARCAYATHAAYTCNYTNGAYTCNGARYTNYTNYTNYTN AARGCNACNTCNTCNGCNACNYTNMGNTGYGTNCARGAYTGYATHCCNYTNYTNCARAAY GCNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TTYGAYMGNCAY TAYTGGGTNCCNTGGACNTCNTAYTAYTTYCAYGCNGCNTTYGCNTCNTCNTTYGCNTTY ATHTTYTTYGGNACNAARAARYTNTTYTCNMGNAAY---MGNAARTTYCARAGYAGYGGN TTYTTYYTNGARTCNYTNYTNGTNGCNGTNACNGGNYTNTTYTCNATGCCNYTNGGNGTN YTNCARTTYATHCCNATHTAYCAYCCNYTNCAYGAYACNYTNAARGTNCAYTCNGARGTN TGYGTNYTNYTNTTYYTNGGNTTYTTYGCNYTNGTNATHTGGTGYTCNGAYMGNCARCCN AAYGAYTTYACNMGNCAYAARGGNGGNAGYYTNTTYAGYYTNATGATGYTNGTNGTNYTN YTNCAYTAYGGNTTYTAYGCNTTYYTNGTNTTYACNGCNAAYCCNAGYAARATHMGNTCN ATHGGNYTNCAYCARCCNGTNGGNCCNTGYAAYAARCARGTNAARGTNCARACNCCNTTY GGNCAYGTNYTNAARAARACNCAYTAYYTNTGYYTNAARAAYTAYTCNGARGAYTAYTTY ACNYTNGAYTGYYTNAARAARCCNCCNGCNGAYAARACNGARTGGTAYACNGTNTGYGGN ACNCCNTAYCCNAAYCAYAARGARTAYATGGTNGTNGTNAGYGCNTTYTGYATGYTNGGN YTNTTYTGGTTYTAYCARGCNYTNTGYMGNTCNGGNCCNCARCCN--------------- ---MGNAAYTTYTTYATHATHTTYGCNAAYATHTGYGTNTTYGCNATGTTYACNATHYTN TTYAARATHCARTCNTCNTCNTCNACNAGYGARTCNAAYGAYGTNCCNAARTTYMGNTAY YTNACNYTNTTYTGYATHGGNTGGGGNATHYTNTTYAAYGCNATHTTYTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TGG ATHCCNACNATHTTYCAYACNGCNTCNATHTGGYTNACNATGGCNYTNGCNATHCARMGN TAYATHTAYGTNTGYCAYTCNTTYAARGCNMGNACNTGGTGYACNGTNAARAAYGTNYTN TAYGGNACNYTNACNATHTAYATHATHTCNTGYYTNACNCAYGCNTCNMGNTTYTTYATH CARTAYCCNGTNGARATHATGMGNCARTCNAARYTNGAYGTNGCNATHATH--------- ------GARGARGARGAYYTNCCNCCNGGNGTNMGNMGNCAYAAYMGNTGYCAYAGYAGY AGYAGYTCNGAYTCNGARAAYGARGTNAARAARAARACNGARGTNGAYTCNTCNGAYTCN GAYTCNGAYAARTCNCCNCAYCARGAYYTNGTNGARTCNAARGCNGARAGY--------- ------AARGARAARGAYACNAAYTCNAARGTN---GGNMGNAGYMGNTCNMGNTCNGAY TCNMGNTCNAARTCNMGNTCNMGNTCNMGNTCN---CCNAARMGNMGNMGNTCNTCNGAR AARAGYMGNMGNTCNMGNTCNMGNTCNMGNGAYMGNMGNCAYMGNMGNGAYMGNAARCAY MGNTCNCAYMGNTCNMGNTCNAARGARMGNMGNMGNTCNMGNGAYMGNCAYMGNCAYAAR AARGAYMGNMGNMGNAGYMGNAGYMGNAGYMGNAGYMGNGAYMGNAARGAYMGNMGNTAY AGYMGNMGNAGYMGNGAYMGNGAYMGNMGNMGNMGNAGYMGNAGYMGNGAY--------- ------------------------------------MGNMGNGAYAGYMGNAGYCCNAGY CCNMGNGAYGGNAARGTNATHAARTTYGGNAAYAARGTNATHAARCCNGGNGCNAGYTTY GGNMGNCCN------AGYTCNAAYTTYTCNAARCCNGTNACNTTYAARGARAARATGMGN CARCARYTNATHAARGCNATHGARGARGGNGCNGAYACNAAYGARGTNYTNGCNAAYAAR GGNGGNTCNACNATHTGYACNCARAGYGCNGGN---GTNCARCARCARAAYATGCCNAAR CCNAARGGNCCNCCNGTNCCNYTNATGGAYACNATHGTNCCNTCNACNGCNAGYYTNGCN GCNATGACNGTNACNGCNTCNGARGCNGCNATGCARTCNATGYTNGCNYTNCARAARGAR GCNACNGARAARACNGGNATHGARATHCCNAARTAYTAYAAYCCNGCNGCNATHAAYCCN ATGAARTAYGCNGARCARGTNCARAARMGNAARYTNYTNTGGTCNAARGCNAARGAYAAR GAYGTNAAYTCNCARTGGCAYGCNACNAGYYTNTCNGGNGAYGCNGAYGAYAARTCNAAR GARAARTTYMGNAARYTNATGGGNATHAARAAYGAYCCNTCN------------------ ---------GCNGCNCCNGARAARGARGARAARCARAARCARYTNTTYGAYCARYTNAAY AARGARTAYGARTTYGCNMGNATGACNACNCAYACNCAYMGNGGNATHGGNYTNGGNTTY AGYTCNTCNTCNCCNCARCARCCNCCN------ATGGCNCCNATHCCNGAYGAYAARCAR GARAARTCNCCNMGNGAYGAR------------------GARTTYACNATHCCNAAYAAY CARGCNCCNATHTTYGGNTCNGAYTCNAGYGAYGARAAYGAY---GAYAAYTAYCCNGAY ACNACNGGNTAYATGYTNYTNCCNCARGARCCNGGNGTNGAYATHGAYGAYTAYGGNAGY GAYAAYAAYGAYGAYGGNGAYTTYAGYAAYGCNGARYTNAGYGCNAAYACNAAYGARCAY ATHAGYAGYGGNGAYAGYGCNAAYAAYAGYAGYAAYGAYAGYYTNCCNGAYGARGTNATH CARTCNGARGCNGGNGCNGCNGCNCCNTAYGTNACNGCNAGY---ACNTCNYTNCAYCCN GARTTYYTNGCNAARTTYCCNGAYGGNAARGTNCCNTCNTAYATGCARGTNCCNGAYGTN CCNYTNAAYMGNAARGAYGCNYTNTGGAAYAARMGNMGN---CARGARAARMGNTCNTCN YTNGARCCNGCNGARGCNAARAAYATHATGAARGCNATGTCNGGNTTYTCNYTNCCNTCN GARAAYGTNCCNGAYTGGGCNAARGGNATHTCNGARGAYCARTGGAAYAAYGTNATHACN CARCARATHAARCCNTCNGAR------------TGYACNACNGAYTCNTCNACNGARGCN GCNAARCARGARGARTGGGTNGCNGARTTYCCNGAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GTNTAYTTYTAYAARCCNYTNMGNATHAGYATHATH TCNTCNTTYCARGTNGAYGAYTCNGCNTCNGAYGTNTAYGARMGNGARCCNTTYGCNGTN GARATHGARTAYYTNMGNACNTCNCAYTCNTCNCAYCARMGNATHGTNYTNYTNGGNYTN CAYGCNAARCCNGAYTCNGTNYTNGARGARYTNCARGARYTNTCNAAYACNGTNAARAAY GTNATGCCNAARTTYCCNAAYTCNCARGGNGTNGTNATHYTNGGNGAYYTNAAYGCNGAY TGYAGYTAYYTNAAYCARAARGARMGNGAYAARYTNGCNYTNTTYAARAARGAYTCNGGN TTYGTNAAYYTNATHCCNGAYGAYGCNGAYACNACNGTNTCNMGNAAYACNGAYTGYGCN TAYGAYMGNGTNATHGTNTAYMGNAAYCCNCARAGYAGYGCNGCNGCNTCNGARTAYYTN YTNCARCARCAYAAYATHTGYTGYGARGARAARGCNGAYGAYATHAGYGAYCAYTAYCCN GTNGARTTYACNYTN------TTYAGYATHAAYYTNTGYYTNGGNCCNACNTAYGAYCAR GAYTGYGCNYTNCAYTTYAAYCCNMGNTTYGAYGARAAYAARGTNGTNMGNAAYCAYCAY GTNGGNGGNGGNTGGGGNCARGARGARACNGCNGGNGGNTGYCCNTTYMGNMGNGGNCAY CAYTTYGARGTNCAYATHAARGCNCAYCAYCAYGGNTTYACNATHACNGTNAAYAAYMGN CAYTTYTGYGAYTTYGCNAAYMGNYTNCCNMGNGARAGYATHCARTAYYTNTAYATGGAR GGNGAYGCNATGATHACNTAYATHCARTTYAARGGNGGN------------CAYCCNTCN TTYCCNCARCCNGGNCARTAYCCNCCNGCNGTNCCNAGYTAYCCNCCNGCNCCNAGYTAY CCNCCNGCNCCNAGYTAYCCNGCNGCNCCNGGNTAYCCNGGN------------CARGGN GGNGGNTTYGGNCCNATHTAYAAYCCNCCNGTNCCNTTYACNACNCCNATHCARGGNGGN GTNGTNCCNGGNAARATHATHTTYATHTCNGGNGTNCCNAAYCCNAAYCCNAGYMGNTTY ACNGTNAAYATGCARTGYGGNCCNTAYGAYTCNGGNGAYTTYGCNATGCAYTTYGAYGTN MGNTTYAAYTAYGGNAGYGAYACNAAYCARATHATHMGNACNCAYAARCARMGNGGNGAY TAYGGNAAYGARGARAARCARYTNAAYTTYTTYCCNTTYTAYCCNAAYGCNCCNTTYMGN ATGATGATHYTNATHGARCARGCNTCNTTYAARATHGCNGTNAAYGAYCARCAYYTNGTN GARTTYTAYCAYMGNATHCAYCCNTTYAAYMGNGCNGAYCAYGTNAAYATHGTNGGNGAY GTNMGNYTNACNGARGTNMGNTTYCARACNTCNGGNTTYGTNCCNAAYTTYYTNGGNAGY TCNGGNACNGGNYTNACNCCNACNYTNACNCCNACNACNYTNGCNACNATHGARCARTCN TTYATGGARATGCARCAYTCNGGNGCNMGNGAYCCNGTNACNCARAGYGGNTTYATGCCN CCNGTNGTNGARCCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGTCN AAYCAYGCNGAYMGNYTNGAYTCNATGGTNGTNGAYGCNGARAARTCNCAYTGGCARCAR GARTGYAGYACNATGGARACNYTNAARGCNAAYTAYMGNGARYTNTCNTCNYTNYTNGAY AARACNCAYGTNAAYCARGTNGARAARAARYTNTCNMGNATHAARCARMGNAARGCNMGN YTNAARMGNTCNMGNCARACNCARTTYCARCARYTNCARGARGTNGAYGARGCNMGNYTN GCNAARGARAARGARATHAGYAAYTGGCARCARMGNYTNYTNTCNGARATGAARGARGGN YTNATGMGNAARAARMGNAARCARGAYATGGAYCARACNYTNAGYGARGTNMGNAARAAR ATHCAYGAYGCNAAYMGNYTNATHGAYACNATGACNGCNYTNGARAARYTNMGNYTNATH MGNCARGAYGCNGCNAARAARMGNGGNGAYACNGAYYTNGGNGARTCNMGNCARAGYTTY GARCARAARATHTCNGAYATGACNMGNYTNGTNMGNTCNCARYTNGARGTNTAYAARGAR GARGARGARCARYTNMGNGGNGTNATHAARTCNGARCARGARGARTCNAGYAARAARGAR AARCARYTNCARGARAGYAARGAYAARGARGARCARMGNCARAARGAYGARGAYYTNAAR AARATGYTNTTYGGNATGGARMGNGAYATHGAYGAYYTNYTNGAYGARGTNGARTCNAAR TAYGTNAAYMGNAARCCNGARTCNAARCCNGARAAYGCNGCNCCNAARAARCCNACNCCN AARCARTCNAARMGNACNACNATGGAYGAYGCNATHAGYGAYATHYTNGAYYTNAAYYTN CCNCAYAAYACNACNTCNGGNAGYACNACNTCNACNACN---ACNAARACNYTNACNACN ACNTCNGCNCCNGAYMGNAARGARGCNACNAARAARTGYTTYCCNATHTTYYTNGGNAGY AGYTCNGAYGARATGGGNYTNGGNACNACNGTNAARACNMGNGTNTGYGAYCARYTNMGN TGYACNGAYTGYGAYTTYMGNGTNTGYTAYTTYGAYAAYTTYTCNTGGAARAARGARACN ACNTAYYTNTTYYTNMGNAAYAAYGTNCCNGAYTTYCARAARYTNAARTCNAAYYTNMGN AARCARAARGGNTGYMGNGCNTAYTGYTGYCARTGYACNTGGMGNGAYGTNACNTCNYTN CARGARGTNACNGAYACNAARYTNAARTGGGTNTGYGGNAARCAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNGARTGYCCNTAYGAYAARGCNCAY ATGATHYTNCCNYTNAARATGCCNTAYCAYYTNTAYAARTGYMGNAARAAYCAYCCNAAY ATGGARATGGCNGTNTGYCCNTAYAAYGCNACNCAYGARGTNAARGCNATHGARYTNAAR TAYCAYATGACNAAYTGYCCNAAYMGNACNYTNYTNGARMGNGAYATGCCNTAYMGNTCN YTNCARAAYGCNATGYTNGGNMGNGARAAYACNGCNATHAARGGNAAYACNGAYYTNCCN CCNGCNGTNCCNATGTCNGGNTTYGCNAAYAGYGGNYTNGARAAYTGGGAYAARGAYGAY TCNATGYTNGARTTYGAYYTNATHTTYATGTTYGGNCCNCCNYTNTTYGAYAARYTNAGY TAYGTNCCNMGNTCNYTNYTNMGNGAYGAYYTNGTNACNYTNAGYAARYTNTTYGARGAY AAYCCNTCNTTYGGNYTNMGNGAYGTNTCNYTNAARATHATHTCNGARYTNAARCARGGN AARCARGTNATHATHGARGAYGARYTNCAYTTYGCNAAYACNMGNAARAGYATHYTNTCN ACNGTNAARAARAARGTNGCNAARTGYGARGCNGTNYTNYTNMGNATHACNCCNGTNCAY GGNYTNGTNCARGTNYTNTGGACNCAYCARAAYGCNCAYGGNCARGGNYTNYTNCCNCAY TGYACNTGYCARAARGTNAAYGCNAAYGCNAGYCAYTGGTTYGAYGCNTCNTGYYTNTCN ATHGAYTAYCARTCNGGNTTYGTNGAYGCNCCNAAYGARAGYGARGGNTTYGARATGAAR GAYGTNCARGCNCAYTAYMGNYTNCARTAYAAYTAYAARTGYGAYTCNCCNGCNYTNTTY ATHCARTGGGARGCNGCNATHTCNGARGCNGGNGAYYTNAAYGCNGCNYTNATHACNATH TGYGGNMGNTGGTCNGCNYTNAAYGARCAYGGNCARATHATHTTYATHMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ACNTTYGAYAAYGTN TAYYTNCCNATHGARGARATHGCNGTNCCNYTNAAYACNGCNTGGTCNACNGTNAARAAY YTNTGYTAYATHGCNGCNAGYGAYGAYTTYMGNAARGCNTTYTCNAARGTNCAYCCNCAR GTNGARMGNGTNAARAAYGARMGNTGGGTNAGYCARCCNYTNTAYTAYTCNTTYAARGAR YTNGARGCNAAYAAYGGNAAYYTNACNGARTTYCARAARMGNYTNGTNAAYYTNTAYYTN YTNGARGGNAARYTNAAYGGNGTNCAYYTNGCNACNGARGARAGYTCNAARYTNGTNGAY MGNYTNAARYTNATHGCNAARGARGGNCARAAYTTYMGNAAYAARGTNMGNATHTGYACN GAYATHTTYTCNCAYGAYGTNACNAAYTTYAAYGAYATHGARGARATGCCNTGGCCNYTN YTNGCNCARATGTCNAARGAYMGNTCNAAYCCNACNMGNGGNCCNTGGMGNGCNACNYTN CARCCNGARACNTAYCARGCNATGATGAGYTAYTGYAGYCAYMGNATGACNMGNTGGAAY YTNTGGAAYGCNCARCAYAAYMGNGCNTCNCAYAAYCAYGCNAGYCARTAYYTNAAYAAY AAYAARYTNATHGARAGYYTNMGNGCNTAYMGNTCNGAYGTNGCNACNATGGTNGGNTAY GAYTCNTTYGCNGARATGTCNATGGARACNAARATGGCNGGNTCNGTNGARAAYGTNYTN ACNATGATHGARACNYTNMGNGCNMGNTTYGCNCCNGTNGTNTGGGARGARATGGCNCAR YTNCARGAYTTYGCNATHTCNGARGGNTTYAARCAYTCNYTNGARATGTGGGAYGTNGCN TAYTGGMGNMGNMGNCARMGNGARCAYYTNTAYAGYYTNAAYAARGAYGCNACNAARGAR TAYTTYCCNGTNAAYTCNGTNYTNYTNGGNYTNTTYGAYYTNTGYACNAAYYTNTTYGGN ATHAAYTTYGARGARGTNACNCCNGARGTNGARGTNTGGCAYCAYGAYGTNMGNTTYTTY AARGTNACNGAYAGYGARTCNGGNGARCAYATHAGYTCNTTYTAYTTYGAYCCNTTYGAY MGNCCNGGNAARAAYTCNCCNGGNTAYATGGGNATHGGNMGNGAYAAYAGYGARCAYGTN GGNACNTGGCCNTAYTCNTAYYTNTGYYTNMGNATHCCNMGNCCNAARTCNTCNTCNGAR CCNGCNYTNATGMGNTTYAARGAYGTNGTNACNYTNTTYACNGARTTYGGNCAYGGNYTN CARCARATGYTNACNAARGTNCCNTAYAGYGARATHTCNGGNCARAARAAYATHGARTGG GAYGCNGTNCAYATHTGYGCNAARTTYATGAARYTNTGGYTNACNAGYCCNAGYGTNGTN AARAGYYTNAGYAGYCAYTAYAGYACNGGNGARCCNATHCCNGAYACNATGYTNTCNGAY ATHYTNMGNGCNTCNCARCAYTGGAGYAAYTTYGAYACNYTNTAYCARYTNTAYGTNTCN GCNTAYGAYATGGARGTNTAYATGACNAAYACNCAYTGGCAYAGYGTNATGAARAAYYTN TGGGARAAYTTYATHCCNYTNCCNYTNAGYGARGARGAYAAYYTNCCNTGYTCNATGATH CCNATHTTYTGYGAYGTNTAYCCNGCNGCNTAYTAYTCNCAYAARTGGTCNGARATGGTN GCNGCNGAYATHTTYTCNGCNTTYGARGARGCNGGNYTNGARAAYCARGARCARATGAAR GTNYTNGGNMGNMGNTTYMGNGARACNTAYYTNTCNYTNGGNGGNGGNGTNCCNTCNTGY GARGTNTTYMGNCARTTYMGNGGNMGNGAYCCNTCNACNCARGCNYTNCARCCNATGGAR AAYAAYAAYGCNATHGTNACNGAR---CCNGARGAYGGNGARTCNAARATHGARGAYGTN AARCCNACNGTNACN------GARGAYACNGAYTCNTCNCCNACNAAYAAYATGAARGGN GGNMGNGGNTAYMGNAARGAYGTNAAYCCNGARACNGARACNGGNAARGCNGCNATHMGN MGNAARATHTGGGAYAAYYTNGARGAYAAYAAYYTNGTNTCNATHCCNMGNCCNTGYCAY TAYMGNATHCCNAAYTTYGARGGNGCNGCNGCNGCNGCNGAYMGNYTNTCNTCNYTNGAR GARTTYAARAARGCNMGNACNATHAARGTNAAYCCNGAYAARGCNCARGARCAYGCNMGN TTYYTNGTNYTNGARGCNGARAARGAYYTNGTNYTNYTNAAYCARAAYCARAARGAYYTN ATGGTNCCNACNCCNGARYTNAARTCNGGNYTNYTNAAYMGNGTNGTNCCNCCNGARGGN GCNAAYAARGARGARYTNMGNCAYTGYTGYACNACNCARGGNGTNAARGARAAYAGYAAR GARATHGGNYTNGARGAYAARGTNAAYYTNGAYYTNATHGTNGTNGGNAGYGTNGCNGTN TCNMGNAAYGGNTAYMGNATHGGNAARGGNAARGGNTAYGCNGAYYTNGARTAYGCNATG ATGMGNACNATGGGNGCNGCNAAYGCNGAYACNATHGTNGTNACNGCNGTNCAYGAYTCN CARGTNGTNGAYATHTCNGAYGAYYTNGTNGARGARCAYGAYATHACNGTNGAYTAYATH YTNACNCCNACNGARYTNATHAARACNAAYTGYACNMGNCCNMGNCCNGCNGGNGTNATH TGGAAYCAYYTNGARGTNTCNAARTTYTAYCARATHCCNGTNYTNMGNCARYTNMGNAAR AAYGARMGNGAYGGNGGNAARGAYGTNYTNYTNAARGAYCARAARGARGARGAYGARGAY CCNGTNGAYGCNATGGARCCNCCNCARCCNMGNMGNTAYGTNMGNTAYTAYAARAAYGAY GGNGGNTAYMGNGGNMGNGGNMGNTAYTAYGGNGGNMGNTAYMGNMGNGGNGGNMGNMGN MGNCARTAYGARGARAAYGGNGARGTNGAYTCN------GGNGCNGAYGGNGAYAAYGAR GGNGGNMGNGTNGGNGGN---AAYMGNMGNCCNCCNCCNMGNAAY--------------- AAYTTYMGNAAYMGNMGNTTYMGNMGNGGNGGN---------AARCCNMGNGCNTCNGAR TCNGARCAYAGYGAYGGNGGNAAYAARGAYGGN---GGNGAYGGNGARGAYMGNCCNMGN CARMGNMGNTAYAAYACNAAYMGNMGNMGNTAYAAYCCNAAYAAYGAYMGNMGNMGNMGN TAYGAY---------AAYMGNMGNGAYAAYMGN---MGNGARGAYCAYTCNGGNAGYGAY GGNGARCARAARTAYTCNGCNGAYGARAGYGGNGARGGNMGNMGNCCNCARMGNCARMGN TTYMGNACNAAYCCNGARGCNGTNGTNTTYGTNGGNGCNYTNTCNMGNAAYYTNMGNGTN AGYGARYTNAARACNGARYTNMGNAGYCAYAAYGTNAAYCCNGTNMGNYTNYTNTGGMGN GGNGCNAAYGGNTAYGCNTTYYTNTTYTTYATGGARCCNGAYAAYGCNAARCARGCNGTN GGNGTNYTNACNGGNMGNGARYTNAAYGGNMGNGARATGAARGTNGARATGGCNAAYATG GAYMGNGAYMGNMGNMGNTCNAAYMGNAAYGAYMGNGGNMGNGARGARGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNGTNCAYTGGTCNTGGGARATHYTNMGNATHYTNGTNACNGGNGAYATH AAYAAYAARGGNYTNGAYAARGARAGYTCNATGATGGARTGGMGNMGN---CCNGARGAR TTYAARTCNYTNCCNACNCCNMGNATHYTNAAYAAYCAYATGCCNTTYCAYATGCARCCN GCNGAYYTNYTNAARAARAARCCNAARGTNGTNYTNTTYTAYMGNAAYTTYAARGAYGTN GCNGTNTCNTTYTAYCAYCAYCAYTGYGCNATHAARGARTAYGGNTAYGARGGNGGNGAY TTYGGNGCNTAYYTNGAYMGNYTNATHGAYGGNYTNATGGARTCNGGNAAYCCNTTYAAR TTYCAYAARGARTGGGAYGCNGCNATHGARGCNAAYCCNGAYYTNCCNGTNTAYTGYTGY GCNTTYGARGAYATGAARGAY--------------------------------------- ------------------------------------------------------------ ------------GAYCCNGTNTCNGARATGMGNAARGTNTCNACNTTYYTNGGNAARCAY TAYGAYGAYAGYTTYYTNCARGAYGCNGCNAAYTCNACNGCNTTYAAYCAYATGAARAAR ACN---------------AARGGNGCNACNAAYCCNATHTTYTAYMGNAARGGNCARGTN GGNGAYTGGAARAAYCAYTTYACNGTNGCNCARAAYGARTGGTTYGAYMGNYTNATH--- ------GARACNGARATGGCNTTYAARTTYMGNTAYTCNYTNYTNYTNAGYTAYGGNATH GGNMGNTTYATGTCNTGYTCNATHGCNMGNTTYCARYTNGCNTTYTTYYTNGTNYTNAAR GARAARYTNAAYTGYGARAGYTGYYTNGCNTTYGAYCCNATGTTYTCNTCNMGNGARATH AAYGTNYTNGARGAYYTNGGNTGYAAYGTNATHTCNCAYAAYGARGARGGNAARMGNGTN TGYAAYTCNCCNACNATHGTNTTYATGCCNCAYTGYGGNAARGCNYTNTAYAAYAAYYTN ATHTGGGCNAAYYTN------YTNGAYAAYYTNGTNATHATHGGNAAYAGYTTYYTNACN ATGATHGARAGYACNCCNCAYMGNYTNYTNAARCARACNGCNAAYTAYGTNATHAARGTN GCNCCNTTYATGGTNGARTCNCCNYTNAARTCNTCNTCNTTYGTNCAYTCNGAYGTNTTY AAYGAYATHTCNATHCAYACNTTYCCNYTNTCNAARYTNAARACNGCNTCNGCNGAYTTY TGGGARGGNAAYAARGARCCNGARTAYTGYGAR---GARGTNGARATHATHCARAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR ATGYTNCARGTNGAYGCNYTNCARTCNAARTTYGAYTCNGAYTCNAARYTNYTNAARGAR AARGARGAYAAYTAYCAYMGNYTNGARGGNYTNGCNMGNGARAAYGAYAGYGARGAYGAR TCNGARTAYAGYCCNTTYGGNMGNCCNTTYCAYGGNGTNAARATHCCNAAYATHGAYYTN AGYGARGAYGARAGYAGYGGNGTNAGYAGYTCNGAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TCNYTN CCNCCNYTNMGNCCNAARATHYTNTCNGTNGAYAARAGYCARAAYTCNGGNATHTCNTTY GGNTCNCAYMGNCCNTTYCCNMGNGARAAYYTNACNTAYYTNAAYCCNYTNGGNGTNGGN TGGTTYGGNCARGTNATHYTNTCNGARGCNYTNMGNATHTCNACNGGNAGYATGMGNAGY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYTTYTCNGCNATHGARGARGARGAY YTNAAYATGYTNTGYMGNTGGMGNGGNGARYTNTAYYTNGARYTNCAYAAYGGNACNTAY ACNACNTGGGGNYTNGTNAARAARGGNAAYMGNGARTGYGARTTYYTNYTNCARGARYTN GARGCNYTNAGYACNATGGCNTGYYTNMGNGAYCCNTCNTTYCAYTAYCCNTAYGAYGAR YTNGAYMGNYTNTGGAARYTNYTNYTNYTNAAYCARTTYCAYGAYGTNYTNCCNGGNTCN TCNATHACNYTNGTNTTYAARGAYGCNATGAARTAYTAYGARGAYATHMGNGTNACNGCN TCNAARYTNACNGGNGTNGCNGTNGAYGCN---ATHACNAARTGYGGNGGNAAYGARACN GGNTCNCARGARTGYGCNCAYATHATHAAYAGYCARGGNTTYGARMGNATHGARGTNATG GAYATH------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARGARGCNACNACNGTNGARATHTGYTCNATHTGYYTNGAR ACNTTYGTNAAYMGNMGNAARGTNYTNAARYTNGARTGYAAYCAYGTNTTYCAYGTNAGY TGYATHGGNAAYTGGYTNAARCARGARGCNAARTGYCCNYTNTGYAARMGNGTNATHCAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGGCNGCNTCNGCNACNGCN------ACNTCNATHAARAGYTCNAARAAY AAYGTNTCNYTNCARMGNGGNAARGARTCNCCNYTNACNGGNTTYATHAAYATHGCNAAR AGYTTYCARMGN------GARAAYAAYAAYGGNYTNAGYYTNGARGAYMGNATGTCNGTN GARCARTGGYTNGAYTAY------------AGYTGY------------GARGARATHACN GGNGAYMGNGARMGNATHGGNGTNGTNGTNAARGAYYTNAAYAGYTTYATGAARGAYAAR GTNTAYTTYGTNGGNGCNACNTCNACNGTNGCNGAYATHTTYATGTAYCAYAGYYTNTTY CCNGTNTTYGARMGNATGTCNTTYCARGARAARGARAARYTNATHAAYYTNTCNMGNTGG TTYAGYCAYATHCARAGYGAYGARAARGCNMGNCARTCNYTNTCNCCNATHACNTTYYTN MGNACNATGATHTAYTCNAGYATHGGNCAYCAY--------------------------- ------AARGCNGTNGCNCCNYTNTCNYTNGCNGARAARTGGGAYAAYGTNGGNYTNYTN GTNGARCCNTCNGGNCCNAARTAYATHAGYCARATHATGYTNACNAAYGAYYTNACNTCN GCNGTNATGGARGARGCNAARGARAARACNGTNGAYYTNATHYTNTCNTAYCAYCCNCCN ATHTTYGCNCCNGTNAARMGNYTNACNCARAGYTCNTGGAARGARMGNATHYTNATHGAR TGYATGGARAAYMGNATHGCNGTNTTYTCNCCNCAYACNTCNTAYGAYGCNGTNGARGAR GGNGTNAAYGAYTGGYTNATHTCNGCNTTYGGNYTNGAYAARGARTCNGTNAARCCNGTN GARGCNACNGARACNTTYGTNAAYAAYAARTCNCAYGTNYTNGARGTNGARYTNGAYCCN TCNAAYYTNGCNGARGTNTGGAARGGNATH---ACNGCNTTYATHCCNAARGAYTCNMGN ATGAARAARGAYAARACNTGYTTYTCNACNCAYGTNGTNMGNACNGGNTCNGTNGARAAR TGGMGNATHMGNATHGARTGYAGYAAYTCNGARYTNATGGAYYTNATGAARGGNGTNGTN ATHTGYCARAAYGCNGARAARTAYACNGTNTCNTCNYTNAAYAARGTNGCNCARAGYAAR TGYGGNATGGGNMGNCARGCNAARYTNGCNGARCCNATHTCNYTNGARAARGCNGTNGAR TGYGTNAARAAYCAYYTNAARYTNAARTAYATHAGYYTNGCNAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARCAYCARACNGARACNYTNTGYATGTAYTGY YTNTCNTGYAARYTNCCNGTNTGYAAYACNTGYTCNAARGAYGGNMGNCAYATGACNCAY GARGTNCARCCNYTNCCNACNYTNTGYAARTCNCARAARAGYGARYTNTCNCARAAYYTN CARTCNYTNTCNGARAARGCNAARTCNGGNACNGARTTYATHCARMGNYTNAARAARATG GCNGAYAGYGTNAGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TCNAARTTYGARGAR GTNATHYTNAARYTNGTNCCNYTNGARCCNGGNGAYTGYYTNGGNTGYAARYTNGTNGGN ACNTCNGTNATGATHGCNAGYGGNATHATHGTNYTNACNTCNGCNATHGCNGGNMGNAAR MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARCARCCNGGNATGAARGTNMGNMGNACNGARATHYTN AARYTNCCNCCNGAYGGNCCNACNTAYCARCARTTYATHGCNAAYACNYTNAAYAARGCN GARTCNYTNGARAARGARTAYACNMGNATHTGYGAYCARACNTCNACNGCNATHYTNGAR YTNGARMGNTAYAARMGNGAYTCNAAYAARGARATHGGNGARYTNAARAARGCNYTNACN AGYATHAARAGYATHCCNGARMGNMGNTCNYTNATGGARAARATHTCNGARTAYAARGAY YTNATGATHAARGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GCNGTNAARACNYTNCCNTAYGAYCCNAAYTAYTTYACNATG CCNCAYCCNGTNYTNGGNAGYTTYATHATHGTNYTNYTNYTNTAYYTNATHGTNGTNACN GTNTCNCCNAAYAGYYTNCCNGARTTYYTNGGNCCNTTYTCNCARTTYGGNAARTAYATG GCNMGNCARCAYTTYAAYGTNYTNATHGGNYTNTGYYTNTTYACNATHATHGCNCAYTGY YTNGARGCNGCNTAYGCNGGNAARGTNTGYCAYGAYMGNMGNTAYTCNGTNACNACNACN ATHAARTGGACNYTNACNGCNYTNGTNTTYGGNTTYCCNTCNYTNATHMGNYTNYTNTCN GTNAARCCNMGNTCNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYCAYACNAARGGNTAY ATGYTNCCNCCNGARYTNYTNGCNAARMGNGARMGNGCNCARMGNGCNGTNGARYTNTCN AAYAARAAYTTYGCNGARTCNACNCARTCNTCNMGNTCNAAR------ATHACNCAYCCN MGNCCNCAYTCNGCNCCNTCNCCNTGGMGNAARAARGARGTNAAYTTYGAYYTNMGNGAR GAYACNMGNTCNCAYCARCCNTGGATHCCNGCNGGNTGYGCNCCNTGYAARCAYCAR--- MGNCCNMGNTCNTCNAGYGCNGARMGNAAYCCNTTYTAYGTNAARGTNATGGARGAYCAR GARYTNTGGGAYTTYYTNCCNGAYMGNCAYTCN---MGNAGYGCNACNACNCARGGNAAR CARMGNGARTCNCCNTAYGGNTAYMGNTCNYTNCCNACNGARMGNCARYTNMGNTCNTGY GAYGTNTCNGARTCNTTYGTNGAYYTNATHGARAARMGNATHYTNCAYMGNATGGARAAR ACNGGNATGAARGGNGGNMGNCARTCNMGNAARGAYCARATGYTNTAYAGYAGYAAYGAR GCNYTNGAYATHACNGAYYTNACNGTNGAYAARTCNTAYAAY---GAYAAYACNAGYYTN AAYTCNACNGCN---------------GARGCNGCNAGYATGATGGAYGCNCCNACNYTN GARAAYATHAARYTNAARYTNGCNGAYATGGARMGNACNMGNMGNGARATHMGNCARMGN TGGTCNTCNYTNAARTTYATGGAYACNACNAAYAARCCNAARCAYAARACN--------- ------AAYGCNTGYCCNGTNGAYCCNCCNGCNYTNGAYTAYACNMGNCAYACNMGNCAY MGNYTNGAYGAYGARTTYGAYGARCCNGTNAAYAARGGNTGGTCNGARGARCCNYTNYTN TTYACNAARTCNMGNAGYGGNACNAARGCNYTNAAYGARCAYAAR--------------- ------------TCNCAYTCNACNACNGTNCARTTYAARCCNCARGTNMGNYTNAAYCCN AGYACNYTNGAYAARATHYTNGARGAYMGNGARMGNTTYGARGGNCAYYTNMGNAARMGN TCNCAYCAYCCNACNGGNAARTTYGAYCCNTGGAGYYTNATGGARGARATHTCNGARGAR ATHYTNAARGARTGYYTNCARGARGTNTCNGARGARGTNGARAARGTNAGYGARGARATH GCNAAYCARATGTAYAARTCNGARTTYATGGTNACNGGNMGNCCNTCNGARTCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARACNYTNGCNATHMGN GGNGARGAYGGNTAYTCNGCNTTYCAYYTNTCNGTNATHAGYGGNGAYTTYMGNGCNGTN AARTAYYTNYTNAARYTNGGNGCNGAYTGYGAYGGNAARTCNGAYTTYGGNAAYTCNGCN ATHTCNYTNGCNATHGCNTAYGGNCAYAAYTGYYTNGTNCCNYTNYTNYTNCARCAYGCN GAYGTNAAYGCNMGNGAYMGNCAYCAYGAYACNTCNYTNATHTTYGCNACNTGGAAYAAY GCNCCNMGNATHGCNTCNGCNYTNATHGARCAYGGNGCNTAYGTNAAYAARAARAAYAAR TAYGGNAGYACNCCNATHTGGAAYGCNGTNTAYAARTCNTCNGTNGARTGYGTNYTNGTN YTNYTNAGYAARAAYGCNAAYATGGAYGCNCCNTGYGARGGNATGGAYATHTTYTTYAAY ---GARAAYAARGGNTGYGARAAR------ATHTCNAARYTNTAYCCNGGNCAYAARCAR TCNGTNYTNTGGGTNGCNGTNGARMGNATHGGN---------CAYAGYYTNAARACNYTN YTNYTNATHYTNGARGCNGGNTAYGAYGTNACNAARGARCAYTGGYTN------TCNATG AAY---------------TGGAARATGACNGTNGAYAARMGNCARGCNYTNGTNGARATG YTNCARTTYYTNTAYAARAAYCCNCARAAYYTNAARGAYYTNTGYMGNAAYACNYTNMGN AARTAYCAYAGYYTNAGYCAYYTNCCNTAYCAYGAYTGGYTNAARGGNYTNTAYYTNCCN TCNACNYTNTAYGAYTTYATGACNYTNTCNTAYATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARMGNGARMGNGARMGNGARGCNMGNGGNMGNCARATH GCNGARGGNTGYACNGGNAARGTNATGGAYATHTTYTTYYTNATGGAYTCNTCNTCNTCN ATHTAYATHAAYGAYTAYATGTCNCARCAYMGNTTYGTNAGYAAYATHGTNMGNMGNTTY GAYATHAGYAAYGARGCNACNMGNGTNGGNATGYTNACNTTYAGYGAYGAYYTNGARMGN CCNGTNYTNGGNYTNGAYCARTAYAAYGGNMGNGCNGARYTNYTNTCNAGYATHTCNATH CARAAYYTNCCNTAYMGNACNGGNGTNACNAAYACNGAYATGGCNATHMGNTAYGTNMGN CARYTNAAYAAYTTYMGNCARGAYATHACNAARGTNATGGTNGTNATGACNGAYGGNGGN TCNMGNTCNCCNGGNTCNACNGCNMGNGARGCNGARYTNGCNMGNAAYTCNGGNTTYTAY ATGTAYGTNGTNGGNATHGGNCARTAYYTNGARGARMGNGARTGGATGGCNATHGCNAGY GAYCCNGAYGAYAGYTTYGTNTTYAAYATHACNAAYCCNMGNYTNATGGARGAYGTNCAR TTYAGYYTNCCNTCNMGNGCNTGYGCNYTNCCNCCNATHATHYTNGGNGGNTCNTGYGAY ATHTCNMGNATGTCNGARGTNTAYTTYGTNGCNGGNMGNACNACNCARGAYGARGCNCAR ACNTTYYTNGARAAYTTYGGNMGNMGNACNMGNGAYATHMGNGAYGTNYTNMGNGTNAAY TAYTAYGTNGAYGGNTGYGTNAAYGTNGARGAYATGACNYTNYTNAAYGARGARCCNTTY YTNTGYGARMGNTAYAAYATHGTNAGYCARGCNGGNGTNGCNGARATGATGTCNMGNGCN GTNMGNGCNATHMGNGARAGYMGNGAYACNGAYACNAAY------------CAYGTNATH GTNYTNTTYGTNGAYGARGARACNATG---GTNAAYMGNTTYGARYTNGCNGAYAGYAGY MGNAGYGTNATHAAYTTYAAYGGNGCNTCNGTNGTNGTNGCNGAYYTNGGNACNMGNACN TAYMGNGAYTTYGCNCARMGNATHGCNTCNAGYMGNAAYAAYYTNGTNAGYTTYACNAGY GGNAGYYTNGCNAGYCARTCNAGYGCNCARATGAAYYTNYTNAAYTCNATHTGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGAGYAARMGNTTYTCNTGGTTYAARMGNTAYGGNCCNGARTTYCAY ATHMGNGGNGAYCARGTNCARATHATHTCNGARCCNMGNCARTTYTAYGARATHYTNAAR GTNAARATHMGNAARGCNAARMGNMGNGTNACNYTNGCNTCNYTNTAYYTNGGNAAYGGN CARYTNGARCARGAYYTNGTNTCNACNATHGAYGAYGCNTGYCARACNGTNYTNTCNCAY GGNTCNTCNGAYYTNGARGTNAAYATHYTNYTNGAYTTYACNMGNGGNTCNMGNGGNAAR GTNAAYTCNMGNACNATGYTNTGYCCNYTNYTNGARAARTGGCCNAAYGTNAARGTNGCN YTNTAYCAYACNCCNGAYYTNMGNGGNYTNYTNAARAARGTNGTNCCNGARMGNTTYAAY GARACNATHGGNYTNACNCAYATGAARGTNTAYYTNATHGAYGAYAGYTTYATHATHAGY GGNGCNAAYYTNAGYAAYGAYTAYTTYACNAAYMGNCARGAYMGNAAYATHYTNTTYAAY GAYTGYTCNCARYTNGCNGAYTTYTTYAAYAAYYTNGTNAARTGYTCNATGTCNTTYTCN YTNCARYTNCAYGGNGAYAAYTCNYTNCAYYTNGCNCCNGAYTGGAAYATHCAYCCNTTY YTNGAYTCNGAYAAYGGNCAYAAYTTYAARYTNGCNGCNAARMGNAARATHGARCARTGY YTNMGNYTN------------CAYCARATHTCNGCNCARGAYGARGCNTCNAGYTAYGTN GGNAAY------GARATHAAYGTNACNAAYGAYYTNAAYACNGAYACNGTNGTNTAYCCN YTNGTNCARATGGGNCCNTTYGGNGTNCARAAYGAYGARYTNGCNACNGTNGARYTNTTY YTNMGNTCNGARCCNTCNGAYYTNATHYTNYTNTCNTCNGGNTAYTTYAAYYTNACNGAY CARTAYATHAAYGTNATHGTNGAYGAYGCNGAYTCNAARTTYAAYATHYTNATGGCNTCN CCNAARGCNAAYGGNTTYYTNGGNGCNAARGGNATHGCNGGNGCNGTNCCNTAYTCNTAY ATHTAYYTNGCNCAYCARTTYTAYAAYAARGTNATHAAYGCNGAYCARTCNCAYMGNATH AAYATGYTNGARTAYGARMGNGARGGNTGGACNTTYCAYAGYAARGGNYTNTGGTAYTAY YTNAARAAYGAYCCNYTNCCNMGNYTNACNYTNATHGGNTCNCCNAAYTTYGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TAYMGNYTNAAYYTNGCNGARATHCCNTTYGTNGCNGGNAARTCN ACNACNCCNAGYCAYTCNYTNGGNGCNAAYGTNCARAARGTNYTNTCNATGATGAARTCN CAYAAYACNGCNYTNTGYTCNCARGTNCAYCCNCAYCAYAAYAAYCAYGGNCARMGNTCN GCNAGYCCNTCNTCNTCNMGNTCNGGNTCNAGYGTNACNTCNTCNATHGAYCARGAYYTN ACNGAYYTNYTNAAYCARYTNCARGARGARTTYMGNCARYTNAGYAGYGAYCAYCARGAY YTNGCNGTNCARYTNAAYGCNGCNACNGAYAARGGNGARMGNYTNGAYYTNGARCARGAR ATHGARGTNATG------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYAARTCNGGNMGNYTNTCNGCNTAYGAYTTY CCNGAYGAYAGYCCNGAYGARGAY------AAYTAYATGGCNYTNGCNGCNMGNTCNAAY MGNAGYAARTGYCCNGTNGAYAGYTCNGARAGYAAR---TCNGCN--------------- ACNGTNGCNGAYGARGGNGGNAARGGNGAYAARAGYGARGCN------YTNGARTCNTCN TCNTCNTCNTCNTAYCCNGAY---GCNGCNAARCCNCCNAARGCNMGNTTYACNAGYMGN YTNAGYAGYGGNGARGTN---GTNGAYACNGGNGTNTCNTCNGTNGAYAGYAGYACNMGN TCNGAYAAYAARCCNGGNCARGAYGGNGCNGGNGTNGAYAGYTCNACN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATHATHGARTCNAARCCNTCN---ACNACNCAYAAYTGYAAYGTNTAYMGNTCNMGNGTN ATHATHGAYGCNCCNATHCARATHGTNAAYGAYACNTTYCCNYTNTGYCCNTTYAAYAAR CAYAARGARTGGGCNCCNGAYATHCARGAYGTNTAYATGGTNGARGAYYTNGGNGGNGGN AAYATHGTNTAYCAYGTNAARTGYACNAGYGTNGGNATG---ATHTCNCCNMGN------ AGYTTYGTNGCNGCNGGNGGNCAYGAYCAYAAYACNYTNCCNATHYTNMGNTAYGGNGTN AGYATHGAYTAYCCNAARCCNGARGAYGGNATGGTNMGNGGNATHTAYGGNCCNTAYGGN ATHMGNYTNGAYCARTAYCARGGNAAYCCNAAYCARACNMGNGCNGARGTNATHYTNCAR ATHGAYTTYAARGGNMGNYTNCCNMGNAARYTNGTNGARAARAAYATHCCNAGYTCNATH GTNACNTCNTAYTGYCAYTAYATGGARTAYATGAARAARAAYGGNYTNYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNGCN YTNGARCARGARAARAARGCNGARTCNAARGCNGARCCNYTNTCNYTNGARCARCARYTN MGNAAYAARGARYTNGARGAYAARGCNGAYAAYGCNGCNYTNGARGTNGTNATHAAYAAR YTNYTNGARTCNGGNCARAAYTGGGTNTCNGARGCNGCNMGNGCNCARYTNGAYGTNGCN AARGCNACNCARAAYCAYAGYTCNYTNYTNAARATHGCNATGGAYGARACNTCNAAYGTN YTNGGNAARGAYTCNGARTGGGARGCNGTNACNGTNGCNTTYAARGARMGNGARAAYGCN GTNACNMGNGCNAAYGARYTNGTNGAYGARGCNAARAARAGYATHGAYAARYTNAARAAR GTNYTNGARGARGCNAARGTNAARAARGTNACNTCNAARAAYCCNGCNATHTAYCCNGCN ACNAARMGNYTNGCNGAYYTNACNAARGARATGTCNGAYGCNGGNGCNAARGTNMGNCAR GCNGAYGCNGAYGCNAARGTNATGYTNAARTAYAARGAYYTNGTNGAYAARGGNMGNAAR CARTTYCARCARGARYTNGARAGYYTNACNCCNGAYGTNAARATGGGNGGNAARAGYMGN AARYTNACNGAYGARGARYTNAAYGCNYTNGTNGCNCAYGCNCAYMGNMGNATHGARCAR YTNCARAARCARATHGCNGARCAYYTNGCNATGGARMGNAARMGNYTNAAYATGGCNYTN GARGCNCARMGNGARGARAGYAARGGNATHACNCARGCNGCNGTNATHGAYGARMGNGCN MGNATGGTNTCNGARTTYGARATGGARAARCARMGNATGGARYTNGARTTYGCNGCNTGG ATGGARGCNGAYGTNMGNAARCARYTNGGNMGNCARGCNGCNGCNCAYAGYGAYCAYYTN AARGAYGTNYTNTCNGTNCARGARCARGARYTNACNAARGAYTTYGARMGNCARATGAAY ATHAARYTNYTNGARGARMGNGARAARTTYCARACNGARACNGCNAGYTGGATHTCNMGN YTNAARGGNATHGARGCNGCNGTNGAYGCNMGNGCNGCNAGYCARAARYTNGCNCAYTCN GCNCARGAYYTNTGGYTNGCNTGYATHGCNYTNAAYTCNACNATHCARTTYGGNGAYGAR AARGARGAYGARGTNYTNATHCCNYTNCARAAYCARGTNGARACNATGYTNATHTCNGCN AAYAARCAYCCNTTYGTNGARACNGTNGCNAAYACNATHCCNCARACNGCNYTNGARMGN GGNGTNTAYACNGARAAYAAYYTNMGNGAYMGNTTYGTNAARGTNGCNAARATHAGYMGN MGNYTNGGNYTNGTNCARGARTCNAAYGCNTCNYTNTAYAARTAYYTNGTNTCNTTYYTN CAYTCNTTYTTYACNGTNAAYACNGTNGCNGCNTAYTCNGARAARGAYTTYGTNTCNYTN GAYGARATGGAYAAYTTYAARYTNGTNGCNAAYGCNCARTAYTGGATGGARAARGGNAGY YTNGAYATGGCNGTNMGNTTYATGAGYCARYTNACNGGNGARTCNMGNAARGCNGCNAGY GAYTGGATHACNGARGCNAARYTNYTNYTNGARACNMGNCARGCNGCNCAYACNATHYTN ACNTTYGCNTCNGCNACNGGNYTNGCNGCNACNTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AAYACNTCNYTNGAYTGGGARTCN GGNAAYATGAGYATHTTYGGNAAYYTNAGYGCNYTNGARGARAGYAAYATHGAYGAYATH GARYTNGARAAYATGGARGAYYTNTTYACNACNATG------------------------ ------------ACNGARACNACNAAYYTNYTNAAYCAYGTNACNAGYTCNGAY---ATG GAYAGYYTN---YTNGTNCCNMGNACNMGNACNGAYACNGTNGGNTCNYTNCCNTCNACN TCNTTYTCNGAYGAYYTNGCNGARGCNTTYGAYGGNYTNGARGGNGCNACNGGNGGNGCN TAYTAYAGYGGN---CAYGAYGGNYTNGAYACNCCNTAYMGNAARATHTCNMGNYTNTCN GARTCNTCNTCNGAYTCNGGNTTYGCNGGNAARGGNGGNTTYAGYTCNTCNTCNTCNTCN GCNTCNTCNTCNTAYTCNGGNAGYCCNTCNGAYTCNTCNATGGGNTAYCAYAAYAAYYTN ACNAAYTCNAAYGAYACNGAYCAYGAYCCNCAYGGNACNAARGCNYTNGCNCAYCARGTN GCNCAYAAYCAYACNTAYAAYACNYTNCCNGGNCAYGTNCCNMGNGARGTNAARAARTAY GCNCCNAARCCNCARTCNAARAARGGNCCNCARTGYMGNGAYGCNAARAARGCNCARGAR YTNAARATHCCNYTNACNATHGAYGARATHGTNGAYTCNCCNGTNGARACNTTYAAYGAY YTNYTNACNAARTAYAGYYTNACNGARGAYCARYTNACNYTNATHMGNGAYATHMGNMGN MGNGGNAARAAYAARYTNGCNGCNCARAAYTGYMGNAARMGNAARGTNGGNGTNATHGTN ACNYTNTCNGAYGARATGTCNGAYYTNCARAARGCNMGNGAYMGNYTNATGGARGARMGN GCNGARATGGARMGNGARACNMGNMGNATGMGNGARAARTTYGGNCAYYTNTAYACNCAY ATHTTYCARTCNYTNMGNGAYGARCAYGGNCARCCNTAYGAYCCNAGYYTNTAYTCNYTN CARCARTCNAGYGAYGGNAAYGTNTTYYTNGTNCCNMGNAAYGTN--------------- ------------------------------------------------------------ ---------------------MGNGCNATHTTYTCNYTNGTNYTNTCNGCNATHGGNYTN GTNTTYGCNATHYTNACNATHYTNAAYYTNACNATGATGYTNGTNMGNAARGGNCCNAAR AARATGYTNTAYAARAARAARMGNGAYGARGARCCNGCNTGYYTNMGNGAYCCNGTNTAY GGNGARCAYGGNTAYYTNCAYYTNGARGARGTNMGNATHCAYTAYGTNATHACNGGNCCN TCNGARAARCCNYTNATGYTNYTNYTNCAYGGNTTYCCNGARTCNTGGTAYTCNTGGMGN CAYCARATHAARGARTTYTCNAARGAYTAYMGNGTNGTNGCNATHGAYATGMGNGGNTAY GGNGAYTCNAGYMGNCCNGCNGGNATHAARMGNTAYACNYTNGARTGYYTNGTNAARGAY GTNAARCARATHATHACNGCNYTNGGNTAYAGYTCNTGYGTNYTNGTNGGNCAYGAYTGG GGNGGNGCNATHTCNTGGGCNTTYGCNGGNTGYTAYCCNGARATGGTNGARAARGTNATH ATHATGAAYAGYCCNCAYGTNMGNGTNTTYAARAARTAYYTNCARAGYCAYYTNGCNCAR TTYAARAARAGYTGGTAYATGTTYTTYTTYYTNGTNCCNTTYYTNCCNGARATHTAYATG GGNYTNAAYGAYTAYAARCCNTTYGAYGTNATGTTYAARGGNMGNAARCARGGNGTNCAR ACNGAYGCNACNACNCARGARGAYGTNGARGTNTAYAARTAYYTNTAYCCNAAYMGNCAY GCNTTYACNGGNCCNATHAAYTAYATHMGNGCNGGNYTNTTYTGYGGNACNTCNTCNTGG YTNTCNCARAARGTNACNAARCCNGTNYTNYTNATHTGGGGNTGYMGNGAYYTNGCNYTN GARACNGGNYTNGCNGARTGYTGYAARGAYTAYGCNTAYGAYATGAARATHGARTAYYTN AARGAYTCNAGYCAYTGGGTNCARATGGAYCAYGCNGARCARGTNAAYTCNTTYATHMGN GARTTYGTNACNACNAAYGTNTGYAAYATHGTNATGTTYTGYAARATHGGNTTYAARGAY ACNTTYAAYATHTCNYTNATGGCNYTNTCNGTNTCNGAYYTNGGNAGYTCNATHATHYTN TTYTGGATGGGNAAYCCNYTNTTYGTNTTYTCNGAYGTNCCNTTYGAYACNYTNTCNYTN GTNTAYYTNACNGGNGGNTGGGTNMGNATHTAYTTYACNMGNACNACNAGYTGGYTNACN GCNATGATHTCNYTNGARMGNTGYYTNTGYATHATHATHCCNYTNAARGTNAARTCNATH YTNACNMGNAARMGNTCNATHTAYACNATHATHATHATHTTYTTYACNATGTCNTTYACN YTNCCNAARACNYTNYTNGGNYTNACNTTYTCNGAYGAYMGNCCNGTNGTNTAYAAYGCN ATHATGAGYGCNAAYYTNGTNYTNGCNTTYATHTCNTTYTTYATHGTNATHYTNAGYACN TCNYTNYTNGTNTCNAARYTNAAYCARAARACNAARTGGMGNGGNGCNTCNGTNAARGGN CARGARAAYYTNGARACNATGACNACNMGNGAYCARMGNGTNAGYAARATGGTNATHYTN ATHTCNTCNGTNTTYATGGGNTGYYTNACNCCNGGNGTNATHYTNTCNATHGTNATGYTN TTYGTNCCNGARTTYAGYAARGGNMGNGCNTAYCAYAAYYTNTTYACNATGGTNTGGGCN ATHAAYCAYATHACNGARGCNATHAAYTCNTCNGTNAAYATHTTYATHTAYTAYAAYATG AGYACNAARTTYMGNAGYACNATHMGNGAYATGTTYATGYTNAAYAARYTNTCNAARTTY TCNMGNTTYATHCCNMGNGTNMGNAAYGCNMGNTGYATG---GGNGGN---GGNGTNCCN GCNCAYTTYAARCCNATHMGNCARGTNTGYGARGARACNAARAGYCAYATGAAYCAYATG CCNGTNCCNCARGGNTCNTGGCARGARGCNTAYAAYGCNACNAAYTCNACNAAYAAYATG ATGYTNYTNGGNTCNTTYACNGTNGCNGTNGCNACNTTYGCNATGYTNYTNYTNACNGAY TGYATHTAYYTNCAYGGNCCNCCNCCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AAYAARYTNGGN CARYTNGGNATHATGACNGCNAARYTNYTNCCNGCNTTYYTNAARTGYTTYAGYGAYTCN TAYGTNTCNATHMGNTGYGARGTNTGYATHACNTGYGGNAAYYTNCARATHAARGARGAR CARGTNYTNGARMGNYTNGTNCAYYTNGCNACNTTYGAYCCNATHTGGAARGTNAARGCN YTNGCNATHCARGCNYTNGGNAARATHGGNGARGTNACNGARGARATHAARGARTGYYTN YTNTGGGCNATGMGNTAYGARGARMGNCCNGGNGTNMGNGCNGARGCNTGYCAYTCNYTN ATHGARYTNAAYATHGAYGAYGARGAYGTNATHGARATHATHCARGARMGNYTNYTNGTN GARTCNAAYCARYTNGTNMGNGARGARATGATHGARGCNYTNTCNYTNTTYGGNTAYAGY ACNTCNGARGAYATGGAYACNGTNGCNCARATHAARGCNGARGTNMGNAARYTNTGYACN MGNAAYATHATHGCNTCNCARATHATHGTNAAYGARAAYGAYGARACNMGNMGNGARCAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TCNGAYACNGTNYTNGTNYTNYTNATGGARGCNMGNGARCARTAYGARTAYGGNATG YTNAARTCNATGTGGGGNAGYGTNYTNCCNATGYTNGGNGAYGTNGARGCNCARGTNAAR TCNYTNATHACNTCNGTNAAYCARGCNCCNAARGTNAGYGARAAYTAYYTNMGNTAYAAY CARYTNACNGARAGYTAYCARGGN---AARATHTCNGAYGTNAGYYTNCARAAYMGNATG TTYYTNGARACNATHAAYATGATGMGNCAYCARTTYGARAAYTCNCCNTCNYTNACNGAR ATHACNTTYAARAAYAAYTCNTCNTGYGCNTTYGCNCAYMGNTCNCCNGGNGARGARYTN TAYTAYMGNACNGGNAARTAYTCNGGNCCNTCNAGYAARGAYGARGCNTGGMGNYTNGAY CARMGNGCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARATGACNATGACNATGGARTCNACNTCNACNATGAARTTYGGNCARACNGGNGAYYTN TAYAGYACNATHCAYTCNGARCARCARAAYYTNGGNGARGTNGARATGTCNGGNAARGAR ACNGARAAYGARYTNACNGCNACNCARGTNYTNAARGARTAYCARATGAAYYTNACNGCN AARGAYGAYAGYGGNGAYGGNAAYGGNGAYTCNTTYGGNAAYGAYAARGGNAAYGGNGAY TCNGGNAAYGARMGNCCNGCNACNGGNGARMGNMGN------------------------ ------------------------GCNGTN------------GGNGAYTTYATGGARATG GTNTAYGARYTNGCNGARTTYGARAAYATGMGNGAYCARGTNMGNAAYACNCCNGARGAY YTNAARCARGAYATHTTYGGNCARCCNCARMGNTGYCARTGYYTNGTNGCNGARGAYACN AARAAYAARGAYGCNGGNATHGTNGGNTAYGCNYTNTAYTTYTTYCCNTAYTCNACNTGG GCNMGNACNTTYATGCAYYTNGARGAYYTNTAYGTNAARCCNGAYTAYMGNGGNAARGGN ATHGGNAARAARATGTAYCARGCNTGYGCNCARATHGCNATHGAYATGGGNTGYAGYMGN YTNCARYTNGARGTNYTNGGNTGGAAYAARCCNGCNAARGARTTYTAYGARAARGTNGGN AAYGARGAYAAYACNGARGTNGARGGNTGGCAYAARATGMGNATGAARMGNGARCARATG GARAARTTYGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNYTN AAYAAYGARTGYGAYGGNYTNGAYGARGAYAAYYTNAARYTNCARGARGARAAYMGN--- ------------------GCNYTNATHMGNGCNATGTCNAARYTNAGYCAYAAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GTNMGNTGYTCNMGNGGNGTNCARACNGARGAYGCNYTNATG GARAGYTAYATHCARACNAAR------CARTTYCARAAYGTNTCNACNGAYAGYGGNCAY YTNTCNGGNTTYTGYGAYCARGARGCNTAYGAYYTNATGGTNAAYGAYAAYGTNCCNGAR AAYTAYTGGAARGAYYTNGCNGARCAYMGNMGNCARGCNYTNAAYGAYACNYTNGARGAR AAYGARAARYTNTGYTGYGARATGAARCARYTNAARAARGARAAYMGNMGNYTNTCNGAY ATHGCNTCNAARGCNGARTAYYTNGARAAYYTNYTNCARGAYGTNYTNACNGARGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATHTGYGCNCAY YTNTCNATHGAYACNGCNCCNGARTCNGTNYTNGAYACNYTNACNGAYGTNTGYCARGAR TTYTTYTGYCARTTYACNMGNCAYYTNGGNGCNGCNACNGAYMGNMGNGCNYTNTAYGGN AGYAAYGGNTTYCCNGAYTCNATHGARMGNGTNYTNCAYGARYTNGGNATGGGNAGYGTN ACNGARYTNCAYTCNTTYTAYCARCARMGNATHGTNGCNTAYCAYAARMGNATGGARMGN CARTGYCARTCNYTNATGGTNGARTAYAAYAGYYTNGTNAARCARCCNCAYTCNACNTCN TCNTCNTCNTCNAGYTCNCCNAAYATGACNGGNGAYACNYTNCARYTNATHMGNATHAAR GARGARCCNAGYACNGGNATHCARTTYCCNYTNYTNGAYGAYAARGAYGARGTNTCNGAR GCNGARCARYTNYTNAAYATHGARAAYYTNGGNCCNTTYGARATHGTNGARCARGARATH CCNACNGGNYTNACNACNGARATGAARGCNAARGGNATGCARGCNAARGGNATHGGNTCN GARAGYMGNGTNTCNAARATGTCNATHTGGGGNTCNGTNGAYGARTCNAGYGARAAYCCN AGYAGY---------GGNCAYGAYATGCCNACNGTNACNACNCCNCARTCNGGNATHCCN ACNACNCCNCARGAYGTNGGNGTNCCNACNCCNMGNGARGGNGGNTCNACNGAYGAYGCN GCNATHCARGARCCNGGNTCNATHAGYAGYACNGAYATHTTYTCNCCNGCNYTNTCN--- GCNCCNAGYAARCCNAARAARAARAARAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNYTNGCNTCNAAYGGNATHGCNTCNTTYTCNYTNAARTAY ATHTGYGAY---GARGTNGCNAARTCNCCNGAYGTNYTNGAYTAYACNTAYTTYYTNAAR GCNTTYGAYTGGYTNTCNMGNCAYCCNAARGTNAAYMGNAARGCNYTNGGNGGNATHGGN AGYTGYGTNGGNGCNGCNTAYGTNTCNYTNATHACNTGGAARMGNCCNGARYTNMGNTGY TAYGTNAGYATHAAYAGYCCNCCNMGNCCNCARGCNCCNACNCARATGGTNGARGGNGAR ATGGTNGARGARYTNTCNTGGCARTGGGAYMGNATHGARGARAARGARGGNGCNTTYGCN TGGMGNTCNATGGGNMGNGTNGARGAYAARATHGCNTCNYTNCCNTAYTGGMGNCAYGGN GCNAARGTNYTNCAYATHCARGGNGARGAYGAYCARTGYGTNAAYCCNGAYTGYYTNMGN GCNAGYCAYGARGTNATHCCNCCNCARTTYMGNAGYAAYTTYGARTTYYTNAGYTAYCCN GGNGCNGGNCAYATHYTNGARCCNCCNCAYATHCCNYTNTGYMGNATGAAYTAYAAYTCN GTNTTYCARTCNATGYTNTTYTGGGGNGGNAARCCNAARCARCAYGCNCAYGCNCARGCN GAYAGYTGGCCNMGNATHGTNAARTTYATGAARAARAAYYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATHCCNGTNATGACNATGMGNAGYGAYGAYGTNATHGTNTGYGCNTAYCCN AARGCNGGNACNCAYTGGGTNTGGGARATHGTNMGNTGYYTNCARGCNGGNACNGTNGCN GTNCCNGTNATHGARAARGAYAAYTAYATGYTNGARTGYAARGGNAARGAYTAYATHGAY TAYYTNCCNTCNCCNMGNGCNYTNAAYTCNCAYYTNMGNTAYAGYCARYTNCCNGARGAR GTNMGNTCNAARAARTGYAARYTNGTNTAYATHAAYMGNAAYCCNAARGAYYTNACNGTN TCNATGCAYCCNTAYTAYTAYGTNCARTAYGTNCCNATHCCNYTNAARCARGAYYTNGAR ATGAARGTNAAYTGGGCNGCNTCNCCNAGYACNGCNCCNAARCARGAYACNAGYAARCAY TTYCAYGTNTTYGTNGGNGAYYTNAGYTCNGAYATHGARCARCAYCARYTNMGNGAYGCN TTYTCNATGTAYGGNGARATHTCNGAYTGYAARATHATHMGNGAYCCNGCNACNATGAAR TCNAARGGNTAYGGNTTYGTNTCNTTYGTNAAYAARGCNGARGCNGARACNGCNATHAGY GGNATGAAYAAYCARTGGYTNGGNACNMGNCCNATHMGNACNAAYTGGGCNACNMGNAAR CCNYTNGCNCCNATGGTNAARGARAAYGCNAARCCNYTNYTNTAYGAYGARGTNTTYGGN CARTCNAGYCCNACNAAYTGYACNGTNTAYTGYGGNGGNGTNGCNAAYGGNYTNACNGAR GARYTNATGMGNAARACNTTYTCNCARTAYGGNACNATHCARGARGTNMGNGTNTTYAAR GAYAARGGNTAYGCNTTYATHMGNTTYAGYACNAARGARGCNGCNACNCARGCNATHTGY GCNGTNCAYGGNACNACNATHAAYGARCARCCNGTNAARTGYTCNTGGGGNAARGARTCN AAYGARTCNAGYCARACNAAYCARCARTCNAAYAGYCCNCCNGTNGTNATGGTNCCNTCN CARCARCARCARCCNATHGCNGCNACNCCNGCNGCNGCNCCNTAYGGN---CARTTYTAY AAYATGAAYTAYTAYCAYGGNGCNCCNTAYGCNGCNGGNACNCCNACNTAYCARAGYGCN GTNCCNACNCARGGNCARTTYATHCCNACNGCNACNGGNCARTGGCCNGGNGGNTAYTCN AAYTAYCARGCNTAYGGNAGYATGAAYGTNCCNGTNGGNGGNTAYGCNGGNYTNCARATG CARCCNGGNGCNCARCARCARCARTTYAGYGGNCARAGYCARGGNATGGTNGGNTAYCCN ATGCARCAR---ATGGCNMGNTCNAAYGTNMGNTAYGARGTNYTNCCNTCNGARGARCAR AAYGTNGCNGCNGARCCNGTNGAYGTNGCNYTNGTNGTNCCNCCNCCNAGYTAYACNGAR AAYGCNGTNATGGARCARGAYGGNGAYAAYCCNGCNTTYGGNCCNGCNAARYTNCCNAAY TAYGTNGAYGCNACNACNYTNCCNACNTAYGARGARGCNGARMGNAGYAARGCNGARGAR ------TCNGGNGCNTCNAGYAAYCAYGAYTGYGARTCNGGNMGNATHAGYTCNATHGAY GGNGTNAAYGARGCNACNATHGGNACNGAYGGNATGTTYATHTGYACNTTYTTYATHTCN TTYYTNTTYAAYTGGYTNGGNTTYYTNYTNTCNYTNTGYYTNTCNAAYACNATHGCNGGN MGNTGYGGNGCNYTNTCNGGNYTNGGNYTNTCNATHGTNAARTGGGTNGTNATHGCNAAR MGNAAYAAYTGGGGNACNGAYTTYGCNGAYGGNGAYTCNTGGYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TCN CARGARATGGARYTNGAYYTNGTNAAYMGNGAYCCNAAYAAYYTNAAYGAYCAYGTNMGN GTNTGYTTYGAYGARGTNATHGGNGARCCNGAYGGNGCNCAYTCNATHAAYTGYGTNTGG ACNAAYAGYTAYMGNTGYTTYAAYTGYTGGAARAGYTGYTGYTAYAAYYTNATGACNATH TTYTGYGCNATHCCNYTNTCNATGTGYTGGGGNTGYGARTTYGCNGCNATHACNTTYTAY CAYGTNTGGCARGTNACNCCNTGYATGMGNGCNTAYATGATHCARTGYGGNTGYATGCAR AARTTYTAYGGNACNTGYYTNCARTGYTGYYTNCARCCNTGYTTYGARTCNATGGGNTTY YTNYTNAAYAAYATHAARGTNACNAAYGTNAGY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------MGNYTNAARYTNGCNYTNGARGARAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CCNGCNGAYAAYGCNYTN GAYTGGTAYYTNGARAAYATGAAYMGNCCNGGNGAYCAYGTNTGYYTNGCNCAYGTNTCN CARTTYCARYTNCAYGTNGGNYTNCCNGGNGCNGCNGTNAAYGTNGARCAYGTNAGYAAR CARGTNCARGARGCNAARGAYAARGCNGARAGYATHATHAGYAARGCNACNYTNATHYTN MGNGGNAARGARATHCARTGYTAYTCNGTNATHMGNTCNAGYACNAARCCNCARTAYACN YTNYTNGARGTNGCNCARGARGARAARGTNGAYCAYATHGTNATGGGNACNMGNGAYYTN GGNTCNATHAARMGNGCNYTNGTNGGNAGYGTNAGYACNGARGTNGTNMGNCAYACNCCN GTNCCNGTNACNATHGTNAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MGNTCNTGG TCNMGNACNAGYATHGGNTCNGTNCCNCCNMGNGGNGAYTCNTCNATGAGYMGNMGNGCN ATGACNCCNACNAARCARGTNTCNYTNCARGCNGTNAARMGNMGNGARGARAGYAGYGTN TCNTTYGTNGAYCAYATHGAYGCNGARAGYGCNMGNYTNAGYGGNGGNGTNMGNAARGCN TGG---------------GAYTTYAAYGAYGAYGAYGTNGAYYTNTCNMGNYTNTCNYTN GGNAGYCAYMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AGYAGYMGNYTNGTNTGGATHGAYYTNGARATGACNGGNYTN GAYGTNGARAARGAYCARATHYTNGARATHGCNTGYYTNGTNACNGAYAARAAYYTNTCN ATHGTNGCNGARGGNCCNGAYYTNGTNATHCAYCARAAYGAYTCNGTNYTNACNGGNATG AGYGARTGGTGYGTNCAYCAYCAYGGNAARTCNGGNYTNACNTCNGCNTCNAARAAYTCN AARATHAGYYTNCARGARGCNGARAARATGGTNYTNGAYTTYGTNGARCARTAYACNCCN AARGGNAARTGYCCNATHGCNGGNAAYTCNGTNGGNACNGAYAARTTYTTYATHGAYMGN CAYATGCCNAARYTNTCNGARCAYYTNCAYTAYMGNATHATHGAYGTNAGYTCNGTNAAR GARGTNTGYMGN---------------------------------MGNTGGTAYCCNGAY GAYTTYAAYGCNGCNCCNCCNAARAARATGGCNCAYMGNGCNYTNGAYGAYATHMGNGAR AGYATHGARGARYTNAARTAYTAYMGNAAYTGYATHTTYAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNGARGGNTAYAARYTNGTNTCNGCNGTNGCNAAYACNAAYMGNCARGCNGARTTY YTNYTNCARYTNCARTCNAAYTGGACNCARGTNGAYTTYTGGTCNGGNCCNGCNGTNTTY CAYCCNAGYACNATGYTNGTNTGYCCNGAYGTNCARCARGCNYTNGARTCNGCNYTNACN CARGARGGNATHCCNTGGCARGARATHAARGCNGAYGTNAAYCARATHGTNGARGGNGGN ATGGCNYTNAAYCCNGTNCAYCAYGGNAARCCNMGNGTNGCNMGNTCNGARGAYATHATH GAYCAYACNAAYTAYCAYAAYTAYAAYGARATHATHTCNTAYYTNMGNCARYTNGARGCN AARTAYCCNGGNAAYYTNGCNYTNAGYAAYYTNACNTAYYTNACNCAYGARGGNMGNGAY ATHGCNATGATHAARGTNAGYAAYMGNAAYGTNTCNGGNAARAARCCNTCNATHGTNYTN GARGCNGGNATHCAYGCNMGNGARTGGATHTCNTCNGCNGCNACNYTNTAYGTNATHGAR AARYTNYTNCARAAYTAYCAYAGYGGNACNMGNGGNGCNCARTGGATGYTNGAYTCNTAY GAYTGGTAYATHATHCCNATGGCNAAYCCNGAYGGNTAYCARTAYACNMGNAGYGGNGGN ATGGARMGNATGTGGMGNAARAAYMGNMGNYTNATHAAYTGGGARTGYGTNGGNGTNGAY YTNAAYMGNAAYTTYGAYGCNCARTTYGGNACNACNGGNGTNTCNAARGAYTGYYTNTCN TTYATHTAYCCNGGNGARAGYGCNTTYTCNGARCCNGARACNGCNAGYATHMGNGARYTN GTNCAYAAYATHAARGAYTCNATHGTNTCNTAYATHGGNYTNCAYGCNTAYTCNCARTTY YTNYTNYTNCCNTGGGGNTAYTCNAARGCNGGNYTNCARCCNACNAAYTCNAARGARYTN CARMGNGTNGCNAARAGYATGGTNAARGCNATHAARAAYACNCAYGGNCARACNTAYAAR GTNGGNACNATHTGGAAYYTNYTNAARTAYGCNGCNAGYGGNTCNTCNATGGAYTGGGCN YTNTCNATHAARCARAAYATGTAYGCNTTYGCNTAYGARYTNMGNCCNGAYGARGAYGAY CCNMGNGGNTTYAAYYTNCCNCCNGAYGARATHGTNCCNACNGGNCARGARYTNYTNGCN AGYYTNGARCARYTNGCNCCNCARCAYGAYCCNACNAGYAARYTNTGYMGNTCNTGGYTN GTNCCNAGYCCNCARCCNCARMGNGARMGNGTNTTYTTYATHGCNTTYYTNACNTGYGTN TAYTCNTGYATGYTNATHGGNTGYYTNATGGCNGCNMGNGTNGGNTAYYTNGTNAGYAAR MGNGTNAARCARGARACNMGNMGNACNACNMGNYTNTAYCAYGARGARGAYAAYGTNCCN GAYATHMGNGARYTNTCNGTNYTNGAYGAYYTNAARMGNCAYCAYAGYYTNTCNTGYYTN GCNYTNTGYGGNATHYTNACNTGGYTNCCNATHGCNATHATGYTNACNYTNCARAARTCN GGNATHCAYATHAGYGARGCNACNYTNGTNTAYTCNAAYATHGCNACNTCNYTNCCNTGY YTNYTNAAYCCNYTNYTNTAYAGYYTNATHYTNGCNMGNTAYMGNGARGGNTAYAARGCN ATHYTNGARMGNTGYMGNMGNAARAARGGNCCNCARAARCCNCAYMGNYTNMGNAAYGTN CARCAYTGYTGYGAYYTNGAYCCNGGNACNGAYACNGAYATHATHTCNTCNTCNAAYGGN CAYMGNTGYGTNCAYGGNMGNCCNAAYCCNACNTTYGAYYTNYTNTTYGTNGTNGTNGTN ---------AGYMGNCARATGTGYTAYACNTGYCARTAYGTNCARAAYGGNCCNGGNAGY GARTGYGCNACNGCNCCNYTNAAYTGGAGYGGNGGNGARCCNMGNATGMGNTGYCCNAAY MGNTGYACNATHYTNGCNGARTAYGAYGCNAAYACNGGNAARCCNACNTTYTTYTAYMGN GGNTGYGCNGTNTCNAAYCCNGCNCARAARGARGGNTGYMGNGAYAGYGGNGCNMGNCAY ATHTGYTTYTAYTCNTGYGGNGAYGGNAARAAYTAYTGYAAYGGNAARTCNATGGCNCAR TCNCCNTAYCAYAGYGCNGAYGAYGGNGAYGGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TTYAAYTCNGTNTTYGGNAGYATGYTNGGNATHGTN GTNACNCCNTTYYTNATHYTNGTNATGYTNGGNAARGAYGGNGAYATHCCNACNCAYAAR ATHTTYTCNCARYTNTTYATGACNGTNGTNGTNCCNYTNTTYATHGGNCARYTNATHMGN AAYTTYAAYTAYTAYTGG------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGTTYAARAARGARAAYYTNMGNAARAAYTTYYTNMGNGTN AARCARAAYATHGAYCARAAYYTNGGNMGNTCNGARAARTCNGARGTNYTNTCNGARGAY CARCARGARAAYGARAARMGNGTNGAYGTNGTNAARCAYGCNTTYCARAAYATHGCNAAR AARTCNGGNGCNGTNYTNCARGCNCARGGNAGYGAYTTYGAYAARMGNYTNAARAARYTN CCNGARACNGGNYTNGGNCAYGCNYTNCARGARTCNGCNCARGGNYTNGGNATHGAYTCN YTNYTNGGNCAYACNTGYCAYGTNTGYGGNGARTGYCARGGNAAYYTNGCNAARGARMGN GTNCARTTYGARACNGTNGTNGARCARGAYTTYATHAARCCNYTNAAYGGNATHGTNGAY GTNGAYATHCCNAGYATHATH--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TTYTAYTTYGTNMGNGCNGAYAARAGYYTNGGNCARAAYGCNTTYTGYMGNGCNTAY GTNAAYTTYYTNAAYGCNGARGAYGTNTTYATHTTYMGNGAYAARTTYGAYGGNTAYGTN TTYYTNGAYGARAARGGNGGNGARTAYCCNGCNGTNGTNGARTTYGCNCCNTTYCAYAAR GTNACNAARAARMGNCARMGNAARGGNGAYTCNAARTGYGGNACNYTNGARCARGAYTCN GAYTAYAARMGNTTYYTNGARGCNYTNGCNAAYCCNCCNGARATHCCNTCNGTNTCNYTN GAYGCNATHGTNGARGARGTNGARGCNAARGARYTNMGNYTNGTNAARYTNAGYATGATG AARACNAAYACNCCNYTNYTNGARTAYYTNAARAARMGNAARGARGARAARMGNATGAAY ATGGTNAARYTNMGNGAYGARMGNMGNMGNGGNGGN---------MGNGAYTAYGAYMGN MGNMGNTCNGGNAARGAYGAYGGNGGNMGN------------------------------ AARGAYMGNGAYMGNGAYMGNCCNATHGAYMGNGAYMGNMGNAARGARMGNGCNMGNGAR YTNGCNMGNGARAARGGNMGNGARMGNMGNMGNGAYMGNGAYMGNGGNGGNGGNGGNGGN MGNCARMGNGAYMGNMGNAGYGARGGNGGNGGNGGNMGNMGNGAYGARGARGARAARCCN AARCCNATHATGYTNYTNAARAAYACNGARMGNGARAAYCAR------GCNAARGARGAR ATHCCNGARGAYMGNGTNAARGGNGTNMGNGARGAYAGYMGNYTNGGNAARGARGARMGN GGNGGN------------------------------------------------------ ------------------------------------------------------------ ---------------TTYCARYTNCCNAAYGAYATHGCNGGNACNACNGARATHGCNGGN GARAAYGARCARGGNTCNTGGGARGTNAAYGTNMGNTAYTGGYTNAARGCNTGGGTNAAR GGNTCNGAYGCNATHCARGARGTNCARCCNGTNGTNATHTAYCARTGYCARGCNYTNGAY YTNMGNGARAGYGTNGCNGGNACNGCNAARGCNTCNGARTTYGARATHAARMGNTTYTTY MGNAAYAARACNATHCAYACNACNGTNAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CCNGARCARATHMGNGGNGGNGGNGARYTNTTYAARTTYCCNTGGACNTCNTAY TCNMGNGTNCARCARTTYCCNTTYAARTTYTAYTGGAARCAYGTNMGNGTNTTYMGNTTY TTYTTYTAYACNAGYGCNYTNGTNTTYCCNYTNATGGTNAARYTNACNAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGACNGAYACNATGCARYTNYTNAARTGY GGNGTNMGNTTYTCNCCNCCNACNYTNGTNYTNACNTAYAARGAYTGGAARTCNGGNAAR ATGMGNMGNMGNTCNATGCCNYTNMGNAAYTTYACNAARCAYTCNGGNGTNGARMGNTTY TGYGARGAYYTNAARGARAAYCCNMGNCAYGCNAARTTYGTNMGNYTNATHTCNCCNYTN CARYTNCARMGNYTNYTNACNATHATHAARGAYAARATHAGYGGNYTNAGYYTNGARGCN AGYATHGCNMGNAAYAARGARYTNGAYACNYTNGAYCCNGARGARAAYYTNAAYAARGTN GAYGARGARACNYTNAARMGNAARAARATGGTNATGAAYTCNTCNTTYGARAARAAYCAR AARAARYTNGGNGAYCCNGAYTTYGARTAYAAYGTNGARGTNGAYTTYGAYGCNGGNGCN ATHGARACNAGYGGNTGGGAYTCNGARGAYTCNGAYATGGAYTTY >papillata YTNGTNATHGCNCCNYTNYTNYTNAGYGTNGCNYTNGCNGGNTAYGAYCCNTAYACNGAY YTNGCNCARYTNTAYMGNATGCARYTNYTNGCNGAYGCNTTYGGNGAYTAYATHCCNGAR AAYYTNCCNATHGAYAAYAAYGAYATHGAR------ATHMGNTCNTAYTGGCCNGARTTY ---------------GCNGCNTCNYTNGAYCCNACNAARTCNTCNGAYGAYATGTAYGGN TCNCARATGTAYAGYGGNGCNCAYATHMGNGAYCARGARCAYATHGARCAYAGYGCNYTN CAYGGNTAYCARTCNGTNGCNGGNGGNACNGCNGARGGNCCNGCNAAYAAYAARATGCAR AARAGYGAYAARCCNYTNCCNGCNTAYTGYAAYCCNCCNAAYCCNTGYCCNATHGGNAAR ACNGCNAARGAYAAYTGYGTNGARGAYTTYGARAAYTCNGCNGAYAAYAAYAARAARYTN YTNAGYGARCARGAYTGYCCNTGYGAYACNGARCAYATGTTYAGYTGYCCNGCNGGNAAR GARACNGTNTCNTCNAARGGNAAYTCNGGNTAYCARCARACNYTNAAYAARGTNATHGAY CARYTNAGYAARATGGGNGCNGGNGAYGAY------GARAAYGGNGGNATHYTNAAYCCN ACNCARCARMGNTTYTCNACNGTNGCNAARAARTCNCCNCAYATHATHCAYAARMGNAAY GARMGN------GTNATGAAYCCNTAYTTYAARGGNACNACNAARGAYATHGCNGCNAAR AARAAYAGYAARYTNTCNCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGNTAYGTN AGYAGY---ATHTGYTTYTTYGGNYTNATHCARGCNYTNTCNGCNGCNAGYYTNGARGAY AARTAYGARCCNATGGTNGCNTTYATHTGYGARMGNCCNGCNATGCAYMGNGGNGTNAAY GGNTGGATHTCNGAYAARACNCARGAYTGYCCNGAYACNYTNGARGAYGTNYTNGCNTAY TGYAARAARGTNTAYCCNGAYCAYAAYATHACNAAYGTNGTNGARTCNTCNMGNTTYTAY AAYATHTCNAAYTGGCCNATGGGNAAYGCNGGNMGNCARCAYACNCAYCAYGTNMGNCCN TTYMGNTGYYTNGTNGGNGGNTTYCARTCNGAYGCNYTNYTNGTNCCNCARCAYTGYGAR TTYGAYCAYMGNCAYGAYATHACNCARTGYAARGARTTYTCNCAYTGGAAYMGNGTNGCN GAYGAYGCNTGYGTNGAYAARGGNATGCAYYTNGARTCNTTYGGNATGYTNYTNTAYTGY ACN---YTNGGNCAYTTYAAYGGNGTNGARTAYGTNTGYTGYCCNGAYAARTCNGGNCCN MGNGTNCAYCCNGARCCN---GARAGYCAYGAYGAYAARCCNGAYAARTGG---GAYAGY CCNGARGARGAYAAYCAYGAYCAYGARGARTAYGAYCARGAYGAYGAYGAYGAYTAYGAR TAYTAYTCNACNTCNACNTCNTCNAGYAGY------------------------------ ---------------GARGARTAYTCNGARGARAAYGTNGTNGAYYTNTAYGARGCNTAY YTNMGNGGNCARACNTTYCCNCCNCARTAYAAYAAYGARCAYAARMGNTAYYTNGCNGCN AARCARMGNATGAARCARAAYCARAARAARAARGTNGCNAARYTNYTNCARGARTGGGAR AARGCNMGNGGNCAYGTNAAYGARGTNMGNAARACNGAYGCNAARACNGCNGAYMGNATG AAYGCNGARATHGCNGARMGNTTYAARCAYYTNTAYGCNTCNTTYAARCARGARGAYGCN TCNGARAAYATGCARYTNGCNGCNYTNCAYCARCARMGNGTNCARGCNTAYYTNAAYGAR AARAARMGNGARGCNATGGAYMGNTAYATGAAYGCNYTNGARAAYGGNAAYATHCCNATG GTNAARAARTAYYTNCAYAGYTAYGTNMGNGCNGARGARAARGAYMGNATGCAYACNGTN AAYCAYTTYGARCAYATHMGNAAYTCNAAYCCNAARGARGCNYTNMGNGTNCAYMGNCAY ATHATHAAYCAYYTNAARYTNTCNGARATGMGNATHGAYCARGCNYTNGARATGYTNACN CAYTAYCCNACNGTNGARMGNGARGTNMGNCCNGARATGGARGARTTYYTNAARMGNTTY AAYGARATHGCNACNAGYATHAARAAYGTNGTNYTNCCNGTNCCNGARGTNAAYAGYCAR GARGARACNAGYGCNAGYAGYGAYTCNGAYAGYTTYACNGCNTCNAAYGAYATHAGYTAY GAYAAY------------GAYAAYACNGAYGGNTAYGAYACNAGYAGYGARGARAARAAR GCNGARGARACNTCNMGNAGYAGYGARGAYGCNTCNACNATHATHGAY------------ ---------------------------GAYGARGTNCARGARGAYGARCAYATHTAYGAR MGNGAYGAYCAYTTYGCNGCNAAYGTNCARTCNGAYACNCAYAGYATHAAYCAYGGNYTN CARTCNTCNGCNACNTCNGGNAGYCARATGGGNAGYACNATHGGNATHGCNYTNGGNAGY GTNAGYGTNTTYGTNATHGTNATHGTNGCNGTNATGATGGTNMGNCAYAAYAARAAYMGN CARTCNGTNTCNCAYGGNTAYGTNGARGTNGAYCCNTCNGCNAGYCCNGARGAYMGNCAY YTNGCNAAYATGCARATGAAYGGNTAYGARAAYCCNACNTAYAARTAYTTYGAR------ ---AARGAYAARYTNTAYAARCARATHACNGTNGARGTNAARGGNCAYGAYCCNGCNGTN ATHAAYAGYTAYCARAARTTYACNACNACNGCNGCNGARCARYTNGGNGTNAARATHGCN AGYATHACNGARCCNCCNMGNGTNATHACNMGNAARAGYYTNYTNAARTCNGTNTTYATH TTYAARAARCAYATGCAYCARTAYGARGCNMGNACNYTNTTYMGNGTNTTYGARTTYAAR CAYYTNACNGARTCNACNGCNYTNACNTTYYTNGARTAYATHCARMGNAAYYTNCCNGAR GGNATGGCNATGAARGTNACNAARCAYGARYTNAARCCNYTNCCNGGNCAYYTNAARCCN CCN---------------------------------GAYTAYTTYAAYGTNATGYTNGGN AGYCARYTNYTNTAYAARTTYGARMGNCCNCARTAYGGNGARATHYTNGCNGARCAYAAR GAYAARCCNATGTCNAGYATHTAYGGNGCNACNCAYYTNYTNMGNYTNTTYGTNMGNYTN GGNGCNATGYTNGCNTTYACNTCNYTNGAYGARMGNACNGTNCAYATHYTNYTNAAYCAY GTNCAYGAYTTYYTNAARTAYATGTCNAARAAYGGNTCNACNYTNTTYAARACNTCNAAY TAYGARATHGCNACNCCNGAYTAYCAYMGNAARGCNATH---YTNGTNAAYTTYATHAAR GARAAYTCNGAYCCNGCNGTNATHCCNCARACNTCNYTNGAYAARCCNGTNGARYTNTCN ATHMGNYTNGGNYTNATHAAYATHMGNAAYGTNGAYTTYACNACNAARGAYGTNGARYTN GAYGCNTGGATHYTNYTNAARTGG---AAYGCNGGNYTNACNTTYGAYCCNTCNGAYTTY AAYAAYYTNCARGAYGTNMGNYTNCCNGCNTCNTTYATHTGGMGNCCNGAYGTNGCNYTN TAYAAYGGNAARATHGAYTTYCCNGARAAYGAYAAYATHGCNAAYTAYGTNGTNGAYGCN AAYGGNGAYGTNYTNTGGGTNCCNCARGTNACNYTNMGNGCNACNTGYGAYGTNAAY--- MGNCAYCARATHTTYTTYAAYACNACNTGYAAYYTNAARATHGGNTCNTGGACNTAYAGY GGNCARTAYATHAAYYTNAARGAY---GAYCCNACNTGGGAYYTNGCNAAYTAYGTNTAY GGNTCNAGYTTYGARYTNGTNAAYACNTCNGCNGARAARCAYACNTCNCAYTAYTCNTGY TGYCCNGARTCNTAYCARGAYATHGGNTTYTCNTTYTCNTTYAARAARMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TCNAARCARMGNTGGATHCCNYTNGAR TCNAAYCCNACNATHYTNAAYAARTAYGTNCAYGGNYTNGGNATGGAYAARGCNTGGAAY TTYGTNGAYGTNTTYGGNYTNGAYCCNGARYTNYTNGCNATGGTNCCNMGNCCNGTNGCN GCNATHGTNYTNYTNTTYCCNGAYACNAARTCN------------CARAAYGCNATHGGN GARTAYYTNAARGARTCNCCNGARGAYYTNTAYTAYACNAARCARACNATHGGNAAYGCN TGYGGNACNGTNGCNYTNGTNCAYGCNYTNGCNAAYAAYCARGAYAARATHACNTTYGAR GARAAYAARGCNTTYTCNAAYTTYYTNAARGCNACNAARGCNATGAAYCCNGARGAYAAR GCNAARCAYYTNGARCARGAYATGGARATGGGNGCNGCNCAYGARGAYTGYGCNCARGAR GGNGAYACNGCNGTNCCNGCNCCNTCNGAYAARGTNAARTGYCAYTTYATHGCNYTNGTN CAYTTYAAYGGNACNYTNGTNGARYTNGAYGGNMGNAARGARGGNCCNGTNACNCAYGGN CCNACNTCNGCNGAYAAYYTNYTNGARGAYGCNGCNGTNGTNGTNAARAARTTYATHGAR AAYAGYCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYAAYYTNTAYATGTGYGTNAAYCARAARACNCAYYTNATG CARTTYCARTTYCAYAARGCNACNCCNAARGCNACNTGYGCNTGGACNTCNGTNAARACN GARMGNAAYGCNGCNGCNAGYGTNTCNGARTTYGAYGARAARATHAARMGNAAYYTNAGY ATGYTNACNTCNGAYCCNYTNGTNACNTAYCCNACNGTNACNGARGCNTGGGGNMGNTTY ATGCARTAYTTYGGNCARGTNTTYAARATHATHTTYTTYGARCCNGTNTTYMGNGAYTAY AAYATGCARGCNYTNACNGARTTYTAYGARGAYAAYGTNCARTAYATHGARYTNMGNTCN YTNTTYGAYGGNATHTAYGAYATHAAYGGNAARGTNTAYGGNAARGARAARGCNTTYCAR ATHTAYMGNGARGTNGCNGARGARTTYAARAARAAYCAYCCNGAYTTYATHGGNGCNAAR TTYATHATGTCNGGNATHMGNGCNAGYCCNAAYGARGTNATHYTNGARCARATHAARGAR ACNATGGCNATGMGNAARGARCAYCCNGAYTCNATGYTNGGNTAYGAYYTNGTNGGNCAR GARGAYCCNAAYAAYCCNYTNATHTAYTAYMGNGAYCARYTNYTNTAYCCNGGNCARATH GAYCCNAAYAAYCCNYTNCCNTAYTTYTTYCAYGCNGCNGARACNAAYTGGCARGGNACN GAYACNGAYTAYAAYYTNYTNGAYGCNYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNTAYCCNGAYTTYGCNGAYGTNGTNGTNGAYGARAAYGGNAARGTNTGG GAYGGNAARACNGGNGARGARYTNAAYAARMGNGGNTAYAAYGGNYTNAAYATGYTNMGN YTNGGNAARMGN---------------------------------CARMGNGARAGYYTN AAYTCNGARTTYACNGAYAGYAAYGAYAARMGNTCNTTYAAYATHYTNMGNYTNGGNAAR MGNAAYYTNAAYATGYTNMGNYTNGGNAARMGNYTNCCNGGNGCNGAYGARGARCARAAR MGNAAYYTNAAYATGYTNMGNYTNGGNAAR---------------------------AAR MGNAAYYTNAAYATGYTNMGNYTNGGNAARMGNCARYTNAAYATGYTNMGNYTNGGNAAR MGNCARYTNAAYATGYTNMGNYTNGGNAARMGNCARYTNAAYATGYTNMGNYTNGGNAAR MGNGGNGTNGTNGGNGAYGARGCNTCNAARMGNAAYYTNCARATGYTNMGNYTNGGNAAR MGNCARGAYGAYGAYGCNGARAARMGNAAYYTNCARATGYTNMGNYTNGGNAARMGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGARAAYCARCARAGYATHYTNYTNGTNYTNTTYGGNTCNYTNATHTGYGCNAGYYTN GTNACNTGYYTNCCNAARMGNTCNGCNGAYGAYATHYTNCARGAYACNTCNGGNATGGTN YTNGAYAARMGNCCNAARTAYATGGAYACNMGNMGNGAYYTNGAYGTNTTYAARGAYYTN GTNYTNATGAGYGTNCARGARYTNGTNGAYGARGGNMGNYTNGARCCNTCNGTNYTNCCN GARGAR------GAYMGNGARACNAGYAARCCNGTNGARAARMGNMGNTAYATGGGNYTN TGYATGCAYMGNCARGCNAAYCARTAYATHCCNTTYCCNTGYYTNMGNACNGGNMGNATG AARGCNGTNYTNTGYYTNYTNYTNATHGGNTGYGCNACNGTNYTNGCNGAYAAYTAYYTN TGYCCNCCNAARAAYGGNGARMGNTTYGARTGYTTYGARTCNGAYCCNYTNTAYMGNGCN TGYYTNACNGAYGGNMGNMGNGGNGAYGCNTAYGTNGTNTGYTCNAARTGYAARMGNAAR TGGGARTTYTGYGTNACNCAYGGNAARTTYCARGARTCNAARAAYCCNACNMGNGAYTGY GGNGCNGAYTAYAARACNACNGARTGYACNCCNGARAAYTCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GCNGCNTTYYTNACNATHGARAARYTNGTNGCNCCN ATHAAYTCNGCNGAYGAYYTNGTNGAYCAYCCNACNATHAARTAYGGNACNAARAARACN GGNACNTCNTGGMGNTTYTTYCARCAYTCNACNATHGAYACNTAYATHCARATGMGNAAR GCNATGGARGARAAYGARGAYGARGTNYTNTTYACNAAYTAYGAYGAYGGNGTNMGNAAR GTNMGNGARTCNAARGGNGAYTAYGCNTTYYTNYTNGARTCNGCNATGAAYTCNTAYCAY GCNCARCARGARCCNTGYGAYACNATGATGGTNGGNGAYCCNYTNGAYAAYAARGGNTAY GGNGTNGCNACNTAYYTNAARTAYCCNYTNMGNCAYAAYATHAAYATHGCNGTNYTNACN YTNGARGARAARGGNGARYTNATHAARYTNCARCARAARTGGTGGYTNGAYAARGGNCAR TGYGGNGCNCARACNTCNGGNAARGARTCN------------------------------ ------------------YTNTTYACNYTNTGYYTNTTYGCNGGNAGYACNTAYGCNGTN TTYTAYATHCCNGGNTCNGTNGTNAGYTAYCCNAARATGGGNAARMGNGCNTTYTAYACN AAYGCNACNGGNAAYMGNTAYCCNYTNATHGGNMGNMGNTCNTCNTCNTCNTCNTCNACN AGYTCNGARGGNCARGGNCCNGGNGARGGNCARGGNCARAAYGCNGARGTNGCNGTNGCN GGNGCNATGAARMGNGGNGTNTTYACNCARGGNCCNCAYMGNAGYYTNCCNMGNGTNGGN MGNTCNGGNGTNTCNGAYGARAAYTCNGARGCNACNGTNAGYGGNAARATHMGNAGYGAR ATHYTNAARGGNYTNGCNGARMGNYTNGARGGNAGYGAYTTYAGYAGYYTNYTNACNGGN CARCARMGNGCNYTNTCNGGNGARAGYACNGAYTCNYTNCCNCARTTYYTNTTYYTNATH TTYGAYGARGAYGGNGAYAAYCARYTNAGYMGNGTNGARTTYACNTCNGGNYTNGCNAAR GTNYTNGAYCARAAYYTNYTNTGYMGNACNGAYGTNATHCCNCARACNTCNYTNGAYACN CCNGTNAARGTNTCNYTNGGNATGTCNYTNACNAAYATHCAYAARGTNGAYACNGARACN MGNAGYGTNTAYYTNGAYGCNTGGATGAAYATGGGNTGGAAYAGYAGYATHACNTTYGAY CCNAGYATGTTYCAYAAYYTNACNTTYACNMGNYTNCAYATGTCNAARATGTGGYTNCCN GAYATHGCNGTNTAYAAYGGN---GARYTNACNYTNGTNAARAAYGARYTNGCNYTNCAY GTNATGCARTCNTCNGGNGAYGCNTTYTGGATHCCNAARACNMGNATHMGNGTNGTNTGY AAYGTNACNGAYGCNTCNYTNGCNGCNAAYACNACNTGYAGYGTNMGNATGGGNTCNTGG ACNTAYGGNAGYTCNCAYYTNTTYYTNGAYAGYAAYCCN---CAYATGGAYATHTCNAGY TTYGAYGCNAAYTCNMGNTAYGARATHGTNCARTAYTCNGCNGTNAARGARTCNAARAAR TAYCCNTGYTGYGARGARYTNTAYGARACNATHYTNTTYATHYTNACNTTYMGNAARMGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------YTNYTNTCNYTNGCN GTNGTNYTNGTNTCNCARGCNCCNTCNACNAARGCNAAYYTNGARCAYGTNTGYAAYCCN GAYTCNTTYGCNAGYCARGGNMGNGGNYTNTGYGGNGCNAAYYTNGTNTCNCARYTNCAY TTYGTNTGYTCNCAYTTYAAYGGN------CCNYTNYTNGAYAARTAYGTNGTNAARMGN AGYTAYCCNACNGARATHGAYMGNGARGTNCAYGAYYTNYTNATHAAYAARAARGAYGCN TTYTCNTTYYTNTCNAARMGNCARAGYAGYCARAAYATHGTNTGYGARTGYTGYGTNAAY TCNTGYAAYTTYATHGARYTNYTNCARTAYTGYGARYTNCCNAAYMGNTAYACNCCNMGN TTYGTNGGNAARMGNTAYACNCCNMGNTTYGTNGGNAARMGNCARGCNCCNMGNTTYATH GGNAARAAYGAYAAYGTNTTYGAYAAYGGNGAYMGNAARCCNCCNMGNTTYATHGGNAAR MGN---------------------------------CCNMGNTTYGTNGGNAARMGNGGN CCNCCNMGNTTYGTNGGNAAR---------------------MGNGGNGCNCCNMGNTTY ATHGGNAARCCNMGNTTYATHGGNAARMGNGCN--------------------------- ------------------------------------------------------------ ---GGNGCNCCNMGNTTYATHGGNAARMGNGGNCCNCCNMGNTTYGTNGGNAARMGNGGN CCNCCNMGNTTYGTNGGNAARMGNGGNCCNCCNMGNTTYGTNGGNAARMGNTCNCCNCCN MGNTTYGTNGGNAARMGNAGYGARGAY------------------------------GAR YTNGARGAYTAYGCNATHYTNAAYGAYACNTAYGAYACNAARMGNGCNGTNCCNMGNTTY GTNGGNAARAARTCNTAYAGYGAYTTYGGNAARMGNGAYGTNCARTCNTTYYTNGAYAAY TGGAGYMGNCARGARGCNATHAARAARYTN---------GTNGAYAAYGAYAARMGNTGG GGNAGYCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TCNTGYATHTCN CCNCCNGTNCARATHCCNCARCCNMGNCAYGTNTCNACNATHTCNTCNGGNACNCCNCCN CCNAAYCARCARYTNTTYCCNGGNCARTCNCCNGGNYTNGTNCARGGNCCNACNTAYAAY TTYATHCARCCNCARTAYCCNCARAGYGARCARTTYYTNTCNTAYCARGCNTAYGGNAGY GCNCCNAAYGAYYTNMGNGGNGCNTCNTCNACNAGYGGNMGNGGNGGNGCNGGNCCNGCN AAYATGGCNCARTCNGGNACNTAYTAYCAYCARACNAAYCARAAYATGMGNCCNTCNCAR CCNCCNCCNCCNAAYCAYTCNCARCCNTAYTTYATHAGYGGNCARAAYAAYATGMGNCAY GCNCCNAAYCCNCCNATGGTNTTYATHCARCCNAAY---------------CCNCCNAAY AAYATGGTNATHCCNGCNAAYATGTAYCARCARACNGCNMGNATGCCNYTNTAYGCNCAR GGNGGNCCNCARTAYCARGCNMGNTTYACNCARCCNAGYGGNATGATGTAYTTYAAYGGN ACNTCNGTNCCNATGCARGCNCCNGGNATGGGNCCNCCNCCNGCNCCNMGNGARAARMGN TTYATHAAYATHAGYGAYCCNAAYACNGGNMGNAAYATHACNAAYGARATHATHAAYTCN CARCARTCNACNGAYGARAARAGYGARCARGARGAYYTNTCNGCNAAYGAYAARGGNGTN GARATHMGNAARAAYTTYACNMGNCARGTNGTNGARMGNATGAARATHGCNGARGGNTCN GCNTCNCCNAAYCAR------CARTCNACNGARCCNGTNAGYYTNTCNCARCARAAYCAR CCNAGYCARGARCAYCCNCARTCNGGNCAYCARCARTCNACNCCNCCNYTNTCNGTNACN CCNGGNCCNGGNTCNATH---------------------------------------ATG MGNCCNCCNTCNATGMGNATGGGNAGYCCNGCNATHAAYYTNAGYGTNCCNCCNCCNCAR YTNCCN---------CCNAAYATGGTNTAYAAYAGYMGNCAYGGNCCNAGYCARCARACN ATGCCNGGNCCNGCNCCNGTNCARACNCARCAYGTNATGTCNTCNAARGGNCCNCAYCCN CCNACNGTNGARGARGCNCCNACNYTNACNMGNCARTCNCCNCCNGCNTCNGARTCNGTN CCNYTNAARGTNGTNCCNCCN---ACNGTNCCNYTNACNCCNYTNGAYACNAARCARYTN AARGCNGAYTCNCARACN------GARTCNGCNGTNACNAARGAYCAYGTNGCNGCNGGN CARCARCCNGTNGARTCNATHAARAARCCNGARAARCCNGARATHGAYGCNGTNAARGAR GAYAGYGGNAGYGGNGCNAGYACNCARGGNAAYAARGAYGGNMGNAARGGNAARAARAAY AARAARGAYTTYAAYMGNAARGARAGYGGNGGNTCNGAYATGGAYGCNTTYATHGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AGYTGGTTYGAYGAYYTNGAY CCNGAYYTNTCN---GGNGAYCCNYTNGGNGAYGAYAGYATGGARGCNTTYATHAAYYTN GAYAARTTYYTNAAYGGNAAYTCNTTYTTYGAYGAR------GARGGNAAYYTNACN--- GTNGARGARGCNGCNGARGTNGCNCCNGTNATHAAYTTYGARCCNGARACNACN------ ---------CARGARCCNACNGTNGARCCNGTNGARGGNACNAARGTNAAYGGNGGNAAR AARCCNTCNMGNAARMGNAARGCN---GGNTCNMGNGARGGNGTNAARACNAGYYTNTAY GARATHCCNGCNACN---------------TCNGTNATHCCNGARATHATHCARTCNACN ACNYTNTCNGAYACNGARYTNGAYCAYGAYTAYAGYACNAARMGNCARMGNATGGCNGTN CCN------------------GARGGNAAYGAYAAYACNCCNTCNACNAGYGGNGCNATG MGNGARTGYACNCARCAYGGNATGGAYATHCCNCARATGGTNYTNGCNAARGCNTCNTGY AAYCCNGTNCARYTNYTNGAYGARAGYYTNGAYAARCARACNATHMGNMGNATHAARAAY AAYCAYGCNTCNAARMGNTCNMGNGARCARMGNAARCARAARTAYGTNGARATGGAYGTN GARGCNGARGARYTNGTNGTNMGNAAYCARCARYTNMGNGARAARATHGTNGAYYTNGAR GTNYTNGCNAARGARATGAARGCNATGYTNGTNGCNAARATGGCNGGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNAARGTNTCNTCNTCNTTY---------GGNGCNCAYGCNMGNTCNTAY TCNGAYTCNACNCCNTCNGCNCARGAYAGYAAYCARGARGTNAGY---AGYTCNGAYATH ACNGARTCNGGNTGYYTNTCNCAYCCNCCNAARGTNCCNGGNACNTCNATGAGYCCNTAY AGYAAYGCNTTYTAYGGNAAYACNCAYAAYTCNGGNATGTAYACNAAYCCNTTYGTNCCN MGNGCNCCNYTNAARTCNGAYGTNGTNTCNACNGAYCARTCNAAYAGYAGYGAYAGYMGN GARGGNYTNATHGCNCCNAGYMGNYTNAAYGCNGCNGTNAAYMGNGAYAGYTCNGARGTN GARGGNACNMGN------TCNTTYCCNAARCARTCNGTNYTNGCNCCNCCNAARYTNACN AGYGCNGTNTTYGGNGGNGGNGGNGCNAGYCAYGAYACNCCNAGYTCNACNTTYAAYTCN TTYAAYTCNTAY---ATHMGNCCNTCNGTNTTYTCNGGNCCNTTYGAYTCNCCNGGNGGN MGNGGNGCNGCNCCNYTNYTNAARCCNGCNAARYTNCCNGAYCCNACNAARTCNTGYGAY AGYAARGCNGAYTCNGCNAGYGARGCNGARGTNAAYGTN---------AAYGCNAARTCN GGNGARGCNTCNTCNGCNAGYGAYMGNYTNAGYGGNGGNGAYGGNACNTCNGGNGGNAGY GARGTNTCNTCNTCNTCNGCNTCNTCNTCNGTNCCNCCNCCNGCNYTNTCNACNCCNACN GAYGGNGARGGNGCNGTNGGNGGNGARAGYACNCCNTAYAAYCARGAYATHGTNCCNGAY ATHAAYAARAAYAAYMGNYTNAARGAYACNTCNGGNGTNTCNAGYAGYTCNCARTCNTTY GTNTTYGGNAGYAAYYTNTCNCARMGNGTNACNGGNATHYTNTCN---TCNCCNGTNGAR AAYGARGCNTCNGCNTCNGCNGGNTTYGTNTTYGGNGARTCNYTNAGYTCNMGNGCNATG GTNGARACNAAYGGNTCNACNYTNCCNCAYAARGAYGAYGARAGYGAYTCNGAYTCNGGN GCNAARYTNAAYCARACNYTNGARGARTCNGCNMGNGARTAYCARGCNAARCAYGARAAY AARACNGARYTNAARGARGTNGARACNATHACNGGNGARGARGARGARTCNAAYGTNYTN CARGCNAAYGCNAARYTNTTYTTYTTYGARACNAGYAAYGARTCNTGGGTNGARMGNGGN MGNGGNACNATHMGNYTNAAYGAYATGTCNGCNMGNGAYAAYACNAAYTTYCARTCNMGN YTNGTNATGMGNACNCARGGNAGYYTNMGNGTNGTNYTNAAYGCNAARATHTGGCCNGGN ATGTCNGTNGARMGNGCNTCNACNMGNTCNATHMGNATHACNGCNATGGAYACNGAYGAR TCNATHAARATHTTYYTNATHACNACNAAYGTNAARGAYTCNGARAAYYTNYTNMGNGCN ATHGAYTGGMGNATHCARCARYTNAARATHCARGARGARCCNGTNMGNCARCAYTCNGAR TCNMGNATHGGNGAYAARMGNAARGCNGAYGAYTCNGAYTTYGARYTNCCNATHAARAAY AARAARGTNAAYAGYTCNCCNGAYCARGGNATHTCNATHACNAARAARGARGARTCNGAY AGYAGYGTNCARGAYCCNGARACNGARGCNTCNTGYGARAGYCAYTCNTCNTCNYTNACN ATHAARTCNGARTCNGAYTTYCARTGYATHCAYTGYGGNTGYAARACNGARAARYTNTAY CAYGAYTTYAARGCNGGNATHACNAARGTNACNAGYTGYAARGTNTGYGGNAAYATHGTN GAYAARTAYGTNGARTAYGAYTCNGCNATHATHYTNYTNGAYGTNYTNYTNYTNCARMGN CARGCNTAYGCNCAYYTNYTNATHAAYGTNGARGTNAAYTCNCAYTGGMGNTTYGCNGTN YTNYTNYTNGTNGTNGARGCNTTYATHAARYTNATHCARCARMGNTCNGAR--------- ------CAYGTNAGYACNAGYGAYGCNAAYAGYTCNTTYGTNGGNGTNGARYTNTAYTTY AAYTAYATHGGNGCNGCNGTNGARYTNATGAGYTTYYTNYTNTGYGTNYTNGCNGTNYTN GCNATHMGNAGYYTNGTNCARACNMGNAGYYTNAARYTNGTNAAYACNTTYYTNATHACN AARGCNATHYTNYTNTCNAAYYTNGGNTCNYTNYTNACNATGCCNGCNYTNYTNTGGGGN AARTCNTGYAGYCCNATHTTYGTNTCNYTNGGNCARATHTTYGTNTGYYTNTCNTCNYTN CARGCNYTNMGNGTNGTNYTNGAY---GGNCCNCAYAARACNYTNGTNGCNGCNGTNGCN GTNGCNTCNGGNATGTGGGTNCARTCNGTNYTNTCNGARGCNYTNAAYACNTGGYTNCAY TCNTTYTAYATGYTNCAYGTNACNYTNAARGARGGNMGNGAYYTNGTNGTNMGNGAYAGY TGYGGNACNAGYGAYCCNTAYGTNAARTTYAARTTYGGNGGNAARCARGTNCAYAARAGY MGNACNATHYTNAARAAYYTNAAYCCNAARTGGGAYGARCARTTYACNATHCCNATHGAY GAYATHAAYAARCCNYTNAAYGTNAARGTNTAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CARMGNGCNGTNATH GARTTYYTNAAYGCNGARGGNTGYTCNCCNATHGARATHCAYACNMGNATGAARMGNGTN TAYGGNGAYGCNTGYGCNGAYTAYAGYACNGTN--------------------------- ------------------------------------------------ATGGCNTCNTCN AAYGTNTCNMGNACNGTNGTNAARTCNYTNAARGGNMGNACNTTY---TCNGCNGCNGCN GCNCARGCNCARMGNGCNCAYAGY---GAYAAYGCNCCNAARTGYTCNGTNAARAARYTN AGYAAYGGNATGAARATHGGNGTNATHCAYTCNAAYTCNCCNATHTCNMGNYTNGCNGTN GTNGCNAAYGCNGGNTCNMGNTTYGARAAYGGNGAYAAYYTNGGNGTNTCNCAYTTYYTN MGNATGTCNTCNMGNATGMGNACNGARAAYATGACNAGYYTNGGNATHACNMGNACNGTN CARCARATGGGNGGNGAYATHACNATHATGGGNACNMGNGARTAYATHTAYTAYAARACN AAYGTNACNMGNAAYTGYGCNGARAARGCNATHAGYATHYTNGARGARATHACNACNAAR CARGCNTAYATHGGNTGGGARATGGCNGAYGTNCARGGNGAYAARAAYGGNATGGCNYTN GAYYTNGCNYTNTAYCAYACNCARCCNYTNGTNMGNGTNGTNGARYTNYTNCAYTCNGCN TCNTTYMGNAAYACNYTNGGNAAYTCNYTNTTYGCNCCNGARCAYATGATHGGNAARTAY ACNCCNGARCARGTNATGCARTAYGTNAARACNCAYTTYAGYGGNGGNMGNATGGCNYTN GTNGGNATHGGNGTNGAYGARGCNGCNYTNGARGAYYTNGCNTCNGCNTTYGARCCNCAY GCNTCNGCNGGNGTNCCNGTNGARAARGCNGCNTAYTAYGGNGGNGGNGARATHMGNCAR AAYACNGGNGGNGAYGTNTCNTAYGTNGCNGTNGGNTGYGGNGGNCCNAGYYTNACNAGY AARGARYTNYTNGCNTCNGARGTNYTNMGNCAYATHYTNGGNGTNGGNCCNTGYATHAAR TAYAGYAGYGGNACNGCNGGNGCNCAYYTNGCNAARGCNGCNGCNGGNGCNACNGAYGCN CCNTTYCAYGTNTCNTGYYTNAAYGCNAAYTAYAGYGAYAAYGGNYTNTTYGGNTTYACN GCNGTNTCNCAYGCNTCNCARATHGARAARGTNYTNCARGCNGCNTGYACNCARYTNAAR GGNYTNYTNTCNGGNAARATHACNGAYCARGAYGTNAGYAARGCNAARAAYCARYTNAAR GCNGARATHTGYATGCARTTYGARAGYCCNGAYGTNYTNYTNAAYTGGYTNGGNGARCAR GCNYTNAAYAGYGAYCARATHGTNACNCCNGAYGAYATHTAYAARATGGTNGAYAAYGTN AAYACNAAYGARGTNAARACNGTNGCNAARAAYATHYTNAAYACNMGNCCNTCNATGGCN GCNATHGGNAAYGTNGCNAAYGTNCCNTAYYTNGAYAARYTNATGGGNGCNAARGGNAGY AARCARAARAGYAARAARAAYAARAARGGNGARGARGARGCN---GGNGAYGCNGTNCAR GARCAR---CARCARCARCCNGARGCNGGNGARGCNACNAAYGARCARAARGTNGARGAR AAYGGNTCNGCNGCNAARGTNGARGARGGNGGNGAYGARAARGARGARGCNAARAGYGAR GARCCNGCNGARGCNAARGCNACNACNGARGARCCNGCNAARGARGARCARAARGARAAR CCNTCNGARGARAARCCNTCNGARCCNGCN------------CCNGCNGCNGARGARCCN GCN------------GCNGCNCCNGARCCNACNAARGAYGARCCNGCNGCNGCNGCNGAR GARCCNAARGCNGARGARCCNGCNTCNGTNGARACNAARGTNGARGARCCNAGYCCNGCN CCNGCNGCNGARGARCCNGCNGARGARCCNGCNAARGARGARACNCARCCNGARCCNGCN ---GCNGARACNCCNGCNCCNGTNGARGARACN------GCNCCNGCNGARGARCCNGCN CCNGARCCNGTNCARGARCCNGCNCCNGTNGARGARCCNTCNGCNCCNGCNGARGARACN CCNGCNCCNGARGTNGCNGARGCN---------------CCNGCNGCNGARGARGCNCCN GTNGARGARACNCCNGCNTCNGTNGCNGARGAR--------------------------- ------------------------------------ACNCCNGCNCCNGCNGCNGARGAR ACNCCNACNGARCARGGNTCNCARAGYGARAGYACNCCNGCNACNCCNACNGAYACNGCN GARACNGGNGCNGCN---------GAYGGNTCNGCNGCNGARACNGGNGARGTNGCNGCN ------GARGARTCNGCNCCNTCNACNGTNMGNACNGARTTYAARTGGGARAAYGGNGGN GAYACNGTNATGGTNAGYGGNACNTTYAAYAGYTGGCARGARAAYATHGCNYTNTCNAAR GARGGNGAYATHTTYACNGGNTTYATGGAYYTNCCNGTNGGNGARTAYYTNTGYAARTTY ATHGTNGAYGARCARTGGGTNGTNAAYAARAAYYTNCCNATHMGNTCNGGNGAYGAYGGN CARGARAAYAAYGTNATHYTNGTNTCNATHATGAARTTYATHCAYTAYYTNTTYTCNYTN YTNGTNTTYATHATGACNATHTCNGCNGTNGGNAAYTTYCARYTNTTYGTNTCNAARCAR ACNYTNAAYTAYTGGGAYGARGARTCNACNGTNATHGGNTGYTTYYTNTGGGAYTTYGCN YTNATHTGYYTNTTYATHGGNCARCAYTCNGTNATGGCNACNCCNTGGTTYAARAAYGAY YTNMGNTCNTGGYTNMGNGTNTCNGTNTCNGARMGNYTNYTNTAYYTNGTNATGACNAGY ACNTCNYTNATGGTNATGATHYTNTAYTGGCAYAGYATHCCNCARGTNTAYYTNTGGTAY ATHCARACNTAYGARACNACNTTYYTNTGGATHTTYTTYYTNYTNTGYCAYTTYGTNGGN TGGYTNYTNATHGGNYTNGARACNATGGCNATGGAYGCNGGNGARTTYTTYGGNTTYTCN CARGTNTAYAAYCAYCAYAAYGGNYTNACNGCNCCNYTNYTNGARAARAARGCNGCNAAR YTNMGNGARATHTAYTCNTGYATGMGNCAYCCNGGNGTNGTNATHYTNAGYATHYTNYTN TGGTTYCAYCCNYTNATGACNYTNGAYMGNGTNYTNYTNGCNTCNGTNTTYACNACNTAY ATGGTNTGGMGNCAYCARYTNGAYGAYACNCAYTGYCARTAYGCNCARAARCAYTTYTCN GTNTCNTAYTCNGARMGNAARCCNCAYCARACNGTNACNTAYGARTAYGTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CARGTNGCNMGNTGGATHTCNTCNATHGGNATGGGNCARTAYTCNAAYAARTTYATH GAYTTYCAYGTNGAYGGNATHCAYYTNYTNACNACNGAYAGYYTNATGYTNGARMGNATG GGNATHAAYAAYGGNCAYGAYGTNYTNTAYATGGARACNMGNATHMGNGARYTNAAYAAY TCNAARMGNYTNTCNGTNTGYCARATHGARGTNYTNCCNCAYTCNTAYTAYMGNGCNYTN AAYTCNGGNGARGARCCNCCNCCNMGNTAYYTNGGNGARYTNYTNCAYTAYTGYGCNACN TTYATHCCNGGNYTNAAYTCNACNCAYGARTAYATHGTNTGYCCNTCNCARGCNACNATH TCNCAYTTYTGGGAYATGGTNTGGGARAAYAARAGYAARGTNATHGTNATGYTNTCNGAY YTNAGYAAYAGYAARGTNAAYACNCARCCNTAYTGGCCNAARAGYATHAAYAARCCNATH ACNTAYGGNAAYTTYAGYYTNAARACNACNAAYTGGATGAAYTTYAARMGNTGYACNATH MGNGAYTTYGTNYTNTCNAARGGNAARACNAAYMGNAARGTNATHCAYTTYAAYATHCCN GCNTGGTGGCARGAYAAYAGYAGYATHTCNACNAGYGAYGTNYTNGAYTTYGTNCARATH GTNMGNGARMGNATHAGYGGNGGNAAYACNGGNCCNATHACNGTNCARTGYACNGCNGGN GTNGGNMGNACNGGNACNATHATHGCNYTNGAYTAYTTYATGCARTAYATHGCNAARCAY TCNCCNGARGAYACNATHGAYGTNTTYAAYTAYGTNYTNMGNATGMGNAARCAYMGNCAR CAYATGGTNCARGAYGARAGYCARTAYATHTTYATHTTYGAYGCNYTNTGYMGNYTNATH AARAARATGGAYAGYGAYATGGARATHATGGGNYTNTAYCARCCNCCNYTNGAYTGYCCN AAYGGNMGNTGYGAYGTNATGTTYACNGCNTTYYTNTAYTGYTTYTCNATHCCNGTNGCN GTNATGATHGTNTTYYTNGTNYTNYTNATHGTNGTNATGTGYTGYTCNMGNMGNGCNTGY ACNTGYAARAARTAYTCNTCNYTNACNTCNGAYGCNAAYGGNATHCARATGGARAGYTAY AAYACNATHMGNMGNGCNTCNGCNAGYYTNMGNTAYATGTCNCARGGNMGNGAYGGNTCN GTNATGGGNAGYMGNGTNGGNTCNTCNGCNACNYTNGAYMGNTCNTAYMGNMGNGCNMGN MGNGGNMGNGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AAYTCNCCNACNAARCARACNAAYTAY ATHATHACNACNACNACNCARTCNCCNYTNAARTCNCARACNTTYGTNYTNAAYACNGCN AAYGGNGTNYTNACNCCNGARCARAAYGTNACNGTNTCNTAYMGNCCNAGYGTNYTNGCN TCNCCNCARYTNTCNCCNTCNCARGCNTCNCCNGTNYTNYTNGGNCAYYTNCARACNGGN GTNCCNCCNCARYTNTTYCARCARGTNGTNTCNACNAAYGTNATHACNTCNACNCARTCN GAYGCNGCNACNGTNTCN------------------------------------------ ------------------------------------------------------------ ---------------------------------------TAYAAYGARTAYYTNGGNTAY YTNYTNCARATHYTNATGYTNGAYGTNAAYYTNGTNGTNTTYATHGARCCNAARGGNACN GGNTTYGTNAARAARAARMGNMGNGGNMGNGARGCNMGNACNYTNATHGTNCCNACNGAR YTNTCNGAYYTNGARTAYTTYCCNYTNYTNCCNMGNATHMGNTCNATHATGAAYAGYGTN TCNTTYCARACNGAYAAYACNAAYTAYCARMGNGGNYTNCCNGARGGNACNGAYCCNYTN TAYAAYYTNGTNACNAAYTCNAARACNACNYTNGTNCAYCARGCNATHGTNTCNAAYCCN TTYAARTCNGAYTAYTTYGTNTGGATGGAYGGNGGNTAYGGNCAYGGNGAYTCNMGNATH TTYCCNCCNAAYGGNGTNTGGTGYCCNCAYCAYYTNYTNMGNCAYCCNGAYAARGTNTCN TTYATHGCNTTYGARAAYYTNAGYGGNGARMGNGCNGARACNGARACNYTNTAYAARCAR AARACNGCNTGGATHGCNGGNGGNYTNTTYTCNGGNGGNACNGCNTCNATGGARMGNTTY TAYTCNYTNCAYAARGAYACNYTNTGGAAYTAYATGAAYAARGGNGTNATHGAYGAYGAY CARACNACNTTYGTNGAYTGYGTNATGAARGAYCAYCARAAYTTYMGNCCNGTNYTNGGN GAYTGGTAYGAYYTNATGAARCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNGTNGGNGARMGNTGYATHYTNGCNCARAAY GCNAAYTCNYTNCAYGTNAGYTAYTGYGCNGTNGAYCCNGTNGGNCCNTGGGAYTGGGAY GARAAYACNGGNYTNATHAARCAYMGNGARYTNAAYAARTGYGTNAARGTNGGNTCNGAY AGYGTNYTNCAYYTNCARTTYTGYGAYAAYAARGAYCARGAYATGCARTGGGTNATHAAY GARGTNTAYCCNTGGAARTGGMGNACNAARTGYATGAARYTNGARAARGTNATHAARACN YTNTCNAAYCAYTGYGTNAARGTNGTNGARCAYCAYGARGAYYTNYTNGTNAARTTYAAR AARAAYCARGAYCARTAYGARMGNYTNAARCARAARTGYAARGARMGNGGNGCNCARATH AARCARGCNMGNGAYGTNYTNATHCCNGTNTCNAAYGARYTNAARYTNYTNMGNGARAAR TAYGARGTNGCNYTNMGNTGYCARATGGARGCNGARTCNTTYGCNATHGARACNACNAAY AARAAYAARAARYTNCAYMGNCARAGYCARGTNYTNACNGCNAARYTNGGNAAYGTNAAY ATHGTNGAYATHAAYATHGAYGAYGAYGARCARGGNGAYGARGARGARAARAARTAYATH GARAARYTNGGNCARAARATHGAYGAYYTNGARGARGARMGNAGYACNYTNTAYATHCAR ATHAARGARATGACNGAYAAYTTYMGNGAYGARTGYACNACNAAYGGNMGNYTNMGNGAR MGNATHGARGCNYTNAARGARGARYTNCARCARGCNAAYACNACNATHAARGARCARACN CARYTNYTNCARAARGTNGCNGTNACNTCNGARATGGCNTTYAARGARTAYCARGAYATG GARCARACNTAYAARAARGARTAYATGGTNMGNAAYGARGCNGARMGNTTYGCNAARMGN YTNTGYTCNGARMGNGAYCARGCNMGNMGNGARAGYTCNATGGCNYTNAGYAARGTNGCN GAYAAYAARAARYTNATGGARGCNATGYTNCARATHCARGAYYTNAAYGCNCARYTNACN CARATGMGNGARGAYTTYGAYAARCARACNYTNGCNYTNGARGARCARYTNAARGCNGCN AARGARGTNTAYAAYGTNGARAAYYTNGARGCNGARAAYGARGARYTNAAYGCNGARAAR GCNACNYTNCARCARAARYTNGARAARATHGARGCNGARATGACNAGYYTNMGNGTNCAR TAYACNGAYYTNCARGARACNTAYAARGCNYTNGARACNAARTAYGARAARGCNACNGCN GTNCCNCCNCCNCCNGCNCCNCCNCCNCCNCCN------CCNGCNGTNAARGTNGGNGGN TTYYTNCARAARATHGTNGGNMGNMGNGGNCARMGNGAYMGNGCNAARGARCAYYTNAAR AARGGNGGNGTNGCNYTNAAYGAYAAYCAYACNAARGCNGTNGARGARATGATGAARMGN ATHCARAGYGGNAAYATHGGNYTNAARCCNGTNYTNCARMGNMGNACNTCNGAYAARCAR TCNYTNCCNGARAARGARGARCCNAGYGCNATGAAYGARYTNCARGGNYTNYTNAGYAAR ATGAARAARGCNAARAGYGAYGAYGAYYTNTCNGTNTTY---GARGARAGYGGNGTNAGY GARGAYTCNGARYTNGGNAARATHTTYMGNAAR---GTNTCN------------------ ---------GARCCNGARMGNACN------------------TCN--------------- ------MGNCCNGTNCCNGCNCCNMGNAARYTNTCNACNATHCARGAYGARGCNGAYGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNAARACNGTNGCNGARYTNGARGCNGAYATGCAYCARAGYTTYCCNAARAARACN GAYAGYCCNGTNCARTCNGTNGCNCARTCNGGNTCNGCNGGNGAYACNACNCCNTTYAAY AARYTNYTNATHATGATGAARGCNTCNTCNGARGCNAAYCARAAYGCNATGMGNAARGAR ACNCCNCCNAAYACNTCNAGYGGNTAYGGNATGGTNCCNAGYCAYAGYGARTTYCCNCAR GCNGTNYTNMGNAAYAARGARCAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNTCNACNGGNAAYTTYAARGARMGNTCNMGNACN TCNACNYTNTCNTCNGGNCARGGNGAYGGNAGYGARGARTGYTCNYTNCCNAGYAAYCAR TCNAAYACNAGYTCNGTNGTNTCNAAYGCNAGYAARACNTAYCCNGARYTNTCNGCNYTN GTNGARGCNACNYTNCCNTCNMGNGAYAAYMGNAGYAGYAARMGNAAYTCNGARCAYMGN TTYTCNMGNCAYAGYCCNMGNGTNCCNACNCCNACNAAYTCNGCNGARGCNYTNGTNTTY ACNATHGAYACNATGCARAGYTAYYTNAAYAAYAGYCARGGNAGYGGNACNTAYYTNCCN CARACNGTNTTYYTNGARACNTCNACNTGYCAYTAYTCNCCNCAYAAYGTNCAYACNGCN CARATHYTNCCNGGNGTNACNYTNGTNYTNYTNTCNCARGCNCCNMGNCAYGTNYTNGCN GAYCCNYTNTAYCARGTNATGAGYAAYATHCARGAYYTNATHTTYGGNMGNMGNACNAAR YTNCCNMGNTCNMGNAGYYTNCAYGTNTAYGARATHATHAAYTCNYTNYTNGGNAARYTN CAYAAYAGYYTNMGNAARTTYAARGGNMGNGARMGNACNYTNATHTCNGAYATHCAYGTN MGNTGGGARAARGARGAYGTNAARCAYMGNYTNYTNGARTAYYTNGARMGNGAYTCNMGN TAYCARATHCCNCCNGAYGTNGARTCNCCNYTNGTNGARATGTAYAARAARYTNMGNGAR YTNTTYTCNYTNYTNTTYYTNTGYCCNGTNCCNGAYAAYCCNCARYTNTGGGARTCNATH TCNCAYYTNMGNGTNGCNATHAAYGCNGARYTNYTNGAYTAYMGNGARTAYYTNAAYGTN AARTCNCARMGNAAYATHACNATGACNAGYTAYTTYGARAARTAYCCNGGNYTNATHCAY TTYATHTTYGTNGAYMGNMGNYTNCAYCARATGACNGTNCCNTCNYTNAAYATHTCNYTN AARGARGGNGARACNGTNAAYACNATHTCNTAYYTNAARGAYAAYATHTGGMGNATGTAY CARCAYATGATGGARAARYTNACNGARGGNTAYACNACNGTNATGYTNMGNGARGGNGAY TTYTAYTAYTCNTAYTTYYTNTGGTTYGARGAYAGYGCNGGNAAYGCNYTNGCNGTNCAR GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNCAYGAYATHTAYCAYTAYAAYACNGARGAR GAYTAYAAYTCNGARAAYMGNTAYGCNAARATHMGNGAYGGNGGNGAYTTYCARGAYACN YTNAGYTCNTTYGTNACNCCN---AARAARAARGCNATHAARCCNTTYMGNGCNGTNYTN CCNACNMGNTCNTCNCCNMGNACNAARYTNTTYAGYMGNAARATHTCNTCNCCNCCNAAR CARGCNGARAGYAAYAARTCNACNTTYAARCAYCCNCARTCNTTYCAYGGNAGYTCNAGY CCNYTNTCNTCNYTNACNCCNGAYTCNGCNTGYCCNCCNCARTCNTCNCARMGNAGYMGN YTNAAYTCNACNGCNAAYCCNGAYGTNGAYCAYCCNTCNTCNACNAGYATHGCN------ ------AGYAGYAGYCAYMGNAARCAYYTNACNCCNGAYYTNGAYYTNACNCARCCNTCN TAYAAYAAYGCN---------------------AAYTTYMGNMGNAARMGNCCNACNTCN TCNTCNTTYACNCCNGARYTNGARCCNAGYMGNCCNTTYAARTTYGCNAGYACNCCNTCN CCNAAYCCNYTNTCNTCNTCNTCNTCNYTNAARTCNGARTTYGARCARCAYTCNTCNTCN TCNTTYTCNYTNCAYAARMGNGTNCCNTTYACNACNGTNYTNGAYATGCCNGARTCNGGN GTNMGNMGNTCNCCNMGNAARYTNTTYGARAARTCNATGAARGCNTCNAARCCN------ ------ACNGARTCNTGYCAYMGNAGYGARAAYGCNGGNCCNTCNGARACNACNGARTCN ACNCCNACNACNAGYATHMGN------------------------------ATGAARMGN TCNGARMGNCAYATGATGMGNYTNAARAGYATHATHGCNAARGTNYTNACNGARAARGGN GTNGARAARGAYAAYGCNATHTAYCARGCNTGYTCNAARAAYYTNYTNAAYGTNAGYATH GTNYTNYTNAARAGYYTNCCNAAYTCNMGNAAYYTNACN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TAYTTYAARGARTTYTTY---CARATGTCNYTNTGGGGNAAYAARTGYGAY YTNTCNATGTCNGCNGGNCARGARAAYAAYGCNACNGARAAYCCNGTNGAYCARYTNGTN MGNYTNATGCCNCAYATHYTNATHGAYAAYACNGAYGAYATHYTNAARATHYTNMGNGAR AARCARAAYAGYGTNGGNGGNAARGGNGCNAARATHTCNTAYGTNYTNGAYAAYGCNGGN TTY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------MGNMGNAARMGNAGYMGNAGY MGNGARMGN---------------------MGNAGYMGNGARMGNAARTCNMGNAGYMGN AGYAARGARMGNMGNMGNMGNGARGARGCNGARAARGGNGGNMGNMGNMGNAGYMGNAGY AARAGYMGNGARMGNMGNMGN---MGNAGYMGNAGYMGNAGYMGNMGNMGNMGNAAYAGY MGNAGYMGNAGYMGNGAYMGNMGNMGNAARAGYMGNTCNCCNMGNMGNMGNTAYAGYMGN AGYCCNYTNMGN---GARMGNYTNCCNGARYTNACNGTNGARGARMGNGAYGTNMGNACN ATHTTYTGYATGCARYTNTCNGCNMGNATHMGNCCNMGNGAYYTNGARGARTTYTTYTCN TCNGTNGGNAARGTNMGNGAYGTNMGNYTNATHACNGAYAAYAARACNMGNMGNTCNAAR GGNATHGCNTAYGTNGARTTYGCNGAYCCNGARTCNGTNACNYTNGCNATGGGNYTNACN GGNCARAARYTNYTNGGNGTNCCNATHATGGTNCARCCNTCNCARGCNGARAARAAYMGN GCNYTNCCNGCNACNCARGCNCCNACNCARAARCAR---GCNCCNGARGGNCCNYTNMGN YTNTAYGTNGGNTCNYTNCAYTTYAAYATHAAYGARGAYATGYTNMGNGGNATHTTYGAR CCNTTYGGNAARATHGTNGAYATHAARATHATGMGNGAYCAYGAYACNCARMGNTCNYTN GGNTTYGGNTTYATHAGYTTYGCNAAYGCNGAYGAYGCNAARAARGCNYTNGAYCARYTN AAYGGNTTYGARYTNGCNGGNMGNCCNATGAARGTNGGNCAYGTNACNGARMGNACNGGN GARCARGGNCARGGN------GCNCARAAYGGNGTNGGNGGNCARYTNGAYACNGAYGAR ATGGAYMGNGCNGGNATHGAYYTNGGNGCNACNGGNMGNYTNCARYTNATGGCNAARYTN GCNGARGGNACNGGNTTYCARATHCCNCARTAYGCNGCNAGYGCNYTNAAYAAYATHACN CCNGCNGCNGCNCCN---GGNGGNCCNGCNACNGCNCCNGCNCCNCCNGTNGCNAAYGCN ATGGCNATGGCNCCNGCNGTNCCNACNACNGTNGCNGCNCARCCNCCNCCNGCNGCN--- ---------ACNAAYGCNCCNCCNATHGCNACNCARTGYTTYATGYTNTCNAAYATGTTY GAYCCNACNTCNGARCCNMGNYTNACNTGGGAYCARGARGTNMGNGAYGAYGTNATHGAY GARTGYAAYAARCAYGGNGGNGTNYTNCAYATHTAYGTNGAYAARAAYTCNCCNCARGGN AAYGTNTAYGTNAARTGYCCNAGYATHTCNGCNGCNGTNGCNTCNGTNAAYTCNYTNCAY GGNMGNTAYTTYGCNGGNMGNGTNATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TTYTGYTCNAARCAYAAYYTNCARCCNYTNAAYTTYTTYTGYGARCCN TGYATHMGNCCNGTNTGYMGNGAYTGYACNGTNYTNGAYCAYAARGARGTNGAYGGNCAY YTNGTNATGGAYYTNGARGARGCNATGGCNAARTAYACNCCNGGNYTNGARACNGCNYTN GCNGARATGGAYGCNGARGCNATHAGYYTNGAYGAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARTTYGGNGAR GAYTTYAARGAYCARYTNGTNTAYYTNGTNTAYGGNTGGATGGCNGGNATHMGNCCNGCN CCNMGNAGYTGGATHATHTGGGAYATGGCNCAYYTNGARCCNCCNAAYYTNAARATGMGN GARGARATGATGCARAARAARAAYAGYAARAARACNACNTCNTTYATHGAYTTYGAYTAY YTNGAYTCNYTNATHTCNACNAAYGCNAGYCARTAYGCNTCNACNATGTCNYTNGCNCAR TCNACNTCNAARTCNTCNACNACNTCNAAYYTNGGN---CCNGCNMGNAARCCNMGNATG CAYGCNMGNATHAGYAAR---CARCAYAARCCNYTNTTYMGNACNTCNTCNCCNAAYAAR ACNCAYTCNCCNAAYTCNACNCARGAYTCNAAYYTNATHGAYGTNGTNGCNGAYGCNCAR TCNAGYCCNMGNGTNAARGGNMGNGAYACNAAR---MGNGGNAGYGAYGCNYTNACNCCN GGNMGNGAYATGAARMGNCARACNGAYGCNYTNACNCCNATHMGNGARATGACNAGY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR YTNGTNCCNTGYYTNTCNTTYTCNGAYGAYAAYAARGARCCNTAYAARATHGARATHTTY AAYACNGCNYTNTCNATHATGGAYATHCAYTCNCAYATHTCNAARACNGARGTNATHGGN ATGYTNGGNGGNMGNTTYAAYGTNGARACNAARTGYYTNACNATHAGYATGGCNGTNCCN TGYAARAGYATGAGYACNGGNATGCARTGYGARATGGAYCCNGTNTCNCARACNYTNGCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TGYCCNGCNTTYYTNMGNCAYAARATGTCN YTNATHTCNCCNCAYATHYTNAARAARTAYTCNATHCCNGTNCARAARATHACNCARGAR GCNGGNGARATHATGATHACNTTYCCNTAYGGNTAYCAYGCNGGNTTYAAYCAYGGNTTY AAYTGYGCNGARTCNACNAAYTTYGCNTCNGARMGNTGGATHGARTAYGGNAARMGNTGY YTNCARTGYGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGCNACNCCNGARGTNCARAARYTN YTNGAYYTNCAYAARAGYYTNGTNTTYGAYACNGGNACNCARAARATHAARTGYMGNYTN ACNAAYCAYGARATGCCNGCNAARGTNAGYGCNATHGARAGYTAYGTNAGYGGNAARAAR TAYAARMGNYTNGCNGGNTTYAAYYTNTTYTCNTAYGARGARCAYAARGARCAYATHGTN CARAAYAARAARAARGAR------CAYGARYTNTTYTGYAAYYTNACNYTNMGNCAYYTN GARAARACNGCNACNGCNATHCARMGNCAYATHAAYGGNMGNAARTAYAARAAYGCNYTN GCNMGNTGGAARGARTGYCARGARACNGGNTCNAARTTYACNCCNCAYAAYCARMGNAAR GCNAARGTNCCNCARYTNAAYGAYGAYGARGARGARGAYAAYGAYGAYAARAARAAYGAY GAYAARAAR------AAYGAYGAYAAYGCNAGYGGNAGYGAY---------GAYGAYGCN GGNAGYGAYGGNACNGTNGTNGARGAYGARAGYACNGAYGAYGAYGARGARGAYGARGAR GAYGAYTAYCCNGCNGCNGAYTTYCARGARATGAGYAAYGARGAY--------------- ------------------------------------GARGARGAR--------------- ---------CCNYTNCCNCCNGGNAGYATGGGNTGGCCNATHATHGGNGARACNATHCAR TTYYTNATHAARGGNACNGARTTYTAYACNGARAARTTYAARCARTTYGGNAAYATHTTY AARTGYAAYATHYTNGGNAGYCCNACNATHMGNGTNACNGGNGCNGARAAYATHMGNACN YTNGTNGAYMGNGARCCNAARCARYTNACNATGAARTGGCCNATGGCNGTNAAYTTYYTN ATGGGNMGNAARAGYYTNCCNACNYTNGTNGGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNYTNGCNGCNTTYMGNAGYYTNCAYMGNGCNMGNAAR GARGTNTTYGCNGGNGAYGARAGYGCNYTNAARGARGTNMGNCAYCARATHAAYTCNCAR TTYMGNGARAARYTNYTNGARACNGAYAARTCNAARATHGARGARAAYYTNGTNYTNGCN AAYGAYGTNGCNTAYYTNYTNMGNTCNACNGTNGTNCARATHCARCARAARCARGCNAAY GAYGAYACNTAYGARYTNMGNATHACNAARAAYACNTAYYTNCCNGARAAYACNCCNTTY GAYCCNACNAARGARATGCCNYTNAARMGNMGNAARACNAARAAYGCNGAYTGYTCNGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGACNGAYGCN CAYMGNATGTTYYTNCARTGYTTYATGTCNAARGGNGTNATGAAYACNGGNGARGTNAAR GTNTGYTAYACNCARTGYAARACNAARTTYTCNGARCCNGTNGAYGARGAR---ACNATG ATHGARATHCCNGAY---------------TTYGTNMGNAARATHAAYTGYGTNATHTCN GTNTTYAAYYTNGARATHAARAARGGNTTYCARGARCAYGAYGGNTCNAGYGTNTAYTGY YTNGTNAAYACNGTNGARAGYCCNATHTCNMGNYTNTCNTCNATHTAYACNCARAAYGAR YTNGARYTNTTYAARAARYTNGTNGARTAYATHGTNGARTCNGAYGAYGGNAARATHGGN TCNACNATHGCNATHAAYYTNACNGARAARYTNGARAARMGNATGGGNAARGARGARGCN CARAAYTTYYTNAAYAGYYTNGARAAYGARAARTGGATHGTNAARGAYAARAAYGGNAAR ATHTCNYTNTCNGTNMGNAGYYTNYTNGARYTNGAYCARTAYYTNCARGAYATGTAYCCN GAYYTNGTNAARAAYTGYAAYATGTGYAGYAARYTNTGYATGCARGGNGAYTCNTGYYTN AGYTGYGGNATHMGNATHCAYYTNAARTGYTCNAARACNTTYTTYTCNAARCARACN--- GAYAARAARTGYCCNAGY------TGYAARYTNCCNTGG------------ATHAARGTN TAYGAYCAYAARMGNGARAGYGCNAARAAYACNMGNTCNCARTTYYTNMGNYTNTCNTTY ACNGTNAAYTGGATHTGGTTYGGNMGNGARTTYCAYYTNGARGTNAARTCNYTNCCNTTY AAYYTNGTNACNGGNTCNYTNCARGCNYTNGARTTYACNGGNACNMGNYTNTGGTAYTGY AAYATGAAYGAYATGTAY---TCNAAYTGYAAYATGGARGARGARYTNGAYAARAGYMGN TTYYTNGAYATGYTNGAYCARATGATHMGNAGYGTNTCNGAYAARAARMGNAARTTYGAY TCNAAYGAYMGNGARTTYYTNTGGAAYCARATHCCN---CARAARAARGGNAGYTCNTCN GGNGCNGCNACNAGYATHAGYGARTGYTTYTCNAARACNACNCCNGARACNACNTGYGAR MGNAARTTYAGYTTYTTYACNTGGTTYTAYGCNYTNYTNAAYACNYTNAGYAGYATHYTN CCNAARYTNTGGGTNGAYGGNATGATHTAYGGNYTNATGACNAARGARCAYGCNGARCAR GTNYTNYTNAAYGAYAARATHCCNCCNYTNACNGTNYTNYTNMGNCCNGTNMGNTCNTTY GTNATGACNCCNAAYTGYAARMGNGCNCARATHAARATHGCNGCNGARATHAARTAYMGN ATHGGNGAYGAYGAYAARATHGGNGTNGTNATHATHGAYGCNGAYGAYTTYGTNCARTAY GGNYTNTAYGGNMGNYTNAARMGNATHMGN---AARYTNGAYATGYTNYTNTCNTCNCAY MGNGARGARGTNMGNMGNGAYGARATHCAYCARAARYTNAARGARGARYTNYTNCAYTCN ATHGARCARGGNTCNCARGGNGAYTCNYTNACNGGNGARTTYGCNGARMGNATHGARCAR YTNGARGTNGCNACNCCNGTNYTNYTNACNGAYCAYCCNAGYATHACNATHTTYAGYCCN GAYAARTTYTGYTGYYTNTTYAARGAYAAYATHAAYCCNTTYTCNTGYGGNTTYTCNMGN TCNCAYTTYTCNAARATHGAYAARGTNTTYGCNACNTTYMGNTCNGARAAYYTNATHCCN TTYYTNYTNTCNAGYACNYTNCCNTCNTGYTTYCAYCARYTNTCNAGYCCNCAYTCNATH ATGATGTGGYTNYTNAGYYTNYTNTCNATHCAYTCNTCNTCNATGGTNGTNAAYYTNATH CAYCARAAYATGACNAGYATHATHCARAAYTTYAGYAAYCAYCCNCARGGNGAYAARAAY GARTCNGCNGAYAARTGGTGYCCNAARCCNATHGARATHGTNMGNATHYTNGTNAAYATG GGNGCNAAYCCNGTNTAYYTNYTNGGNGAYCARGCNYTNTAYTCNACNGARGAYATHAAR GARCAYYTNTCNGTNGARAAYGAYGARAAYGAYTCNATGCCNACNAARTCNTCNGGNMGN GTNAARGTNGARAAYTGYMGNTGYGTNTTYGARATHYTNACNMGNTAYTTYCARACNAAR CCNGCNTAYACNAARGARGARACNAAYYTNATGATHTGYYTNATHACNAARGTNTCNYTN GAYACNTCNTTYCARAAYTTYGARYTNCAYCAYGTNTTYCARGAYYTNYTNTCNTCNYTN YTNGARTGYTAYACNGAYTCNGARTGGTTYTCNGTNGTNCCNTCNYTNTGYCAYGARTTY AGYACNATHCCNCARGAYCAYCAYTGYTCNGTNTAYYTNGTNGAYYTNATGCCNYTNACN GCNMGNGGNAAYTAYATHCARATHMGNYTNAGYTTYYTNYTNYTNTGYACNACNYTNGAY TAYGARMGNAARGAYGARCAYGTNYTNCARYTNGAYTCNATHTCNCCNTCNMGNATHTCN CARYTNGGNMGNGAYTCNAGYGARGAYCARCCNTCNTCNTAYYTNTAYTCNTGYYTNCAY MGNYTNATHAARGARAAYGTNAGYATGATGAAYTCNGCNATHACNYTNYTNGAYMGNGCN GTNGGNGAYGARTCNAAYMGNAAYGCNCARCCNAARGAYGARYTNGAYTTYYTNACNAGY CARGTNMGNATGGTNATHMGNGAYATHMGNGAYAGYATHAAYAAYYTNGAYYTNTCNAAR ATHAARGAYMGNATGACNATHATGACNAARAARTGGATGATGATGTCNACNCARCAYACN AARAGYATHCARMGNAGYATHTTYTCNTGG------GTNACNTCNCAYATGAGYGTNCAR GARGARAARYTNAARGAYAGYGTNTCNAGYGAYGCNGAYGARGARATGGAYATGAGYGGN MGNAAYMGNAARGTNMGNGTNTGGGGNMGNYTNMGNCCNACNGCNAAYTTYGCNTAYGAR AAYGTNGARGTNYTNCCNGAYAAYAARGGNATHAAYATHCAYATGMGNMGNGAYCCNAAR AARGGNGTNGTNAAYAAYCARATHYTNGAYTGGTCNTTYAARYTNGAYGGNATHTTYAAY AAYGCNGAYCARGARGTNGTNTAYAAYACNGTNACNTCNGAYGTNGTNTCNAGYTCNYTN GAYGGNTAYAAYGGNACNYTNATGTGYTAYGGNCARACNGGNGCNGGNAARACNTTYACN ATGACNGGNGCNACNGARAGYTAYMGNCAYMGNGGNYTNATHCCNMGNGCNATHTCNCAR YTNTTYMGNCARATHGARGAYMGNYTNGARTAYAGYATHACNGTNMGNGTNTCNTAYATG GARATHTAYAAYGARCARATGTTYGAYYTNYTNGGNACNTTYCCNGARGCNAGYTGGTCN AAY------AARGAYATHAAYTGYAGYCCNGAYCCNATGGTNATHTCNGARAAYCARGGN GGNGTNTTYGTNAARGGNYTNTCNTGYCAYYTNGCNCARAAYGARGARGARGCNYTNAAY YTNYTNTTYGARGGNGARACNAAYMGNTCNATHGCNGCNCAYTCNYTNAAYAARGTNTCN TCNMGNTCNCAYTGYATHTTYACNGTNTAYATHGARTCNMGNTCNMGNGTNCARTCNAAY GCNAARTAYACNGTNTCNAARYTNAAYTTYGTNGAYYTNGCNGGNTCNGARMGNYTNAGY AARACNAARTCNGARGGNAARACNAARGARGARGCNATGTAYATHAAYAARTCNYTNTCN TTYYTNGARCARGTNGTNATHGCNYTNGCNTCNAARACNMGNGARCAYGTNCCNTTYMGN CARTCNAARYTNACNCAYTTYYTNAARGAYTCNATHGGNGGNAAYTGYAAYACNGTNYTN ATHGCNAAYATGTGGGCNGARAARCCNCARATGGARGARACNGTNTCNACNYTNMGNTTY GCNACNMGNATGATGTGYGTNGCNAGYGARCCNGCNGTNAAYGARATHTAYGAYCCNGCN YTNYTNGTNAARAARYTNCARAARGARATHTGYCAYYTNAARTCNGARYTNGCNATGCAY GAYACNYTNACNAAYMGNAGYATGGTNTCNTAYGAYCCNYTNTCNGARCARCARAARTAY GARATHMGNACNCARGTNMGNMGNTTYYTNGARGGNAGYYTNGAYGARATHGAYATHGTN AAYYTNMGNCARATHGCNGGNTGYTTYAARACNTTYAARGAYYTNTAYCARGAYATGGAR AARGARATGGARGCNAARYTNMGNGARAARTTYATGYTNATHGAYAARACNGAYCCNAAY TCNATHTCNGCNGCNCARCAR--------------------------------------- ------GCNGGNATHCCNATHGCNGAYGAYGGNACNTAYGTNGGNGARYTNGARGGNGGN GGNTTYGGNATHGGNTCNGCNCCNAARAGYACNAARGGNGAYAGYTCNGCNGTNGTNCAR YTNMGNAARAARGARMGNGARMGNGARMGNAARMGNGGNTCNMGNGGNGCNAAYAGYCCN ATHGCNGGNAARACNTCNTCNAGYCCNTCNCARAGYGTNAARGGNGARMGNAARGCNGAR ACNCCNCCNACNCCNGGNGGN------GGNGARMGNGTNGARAARGAYCCNGARGGNTCN GCNTCNCCNGTNAGYTCNACNGGNAAYYTNTCNMGNGCNGAYMGNAGYCARMGNCCNMGN GCNGCNYTNGARGARCCNGARAGY------------------------GAYACNCCNCCN TCNMGNAGYGCNGCNTTYGARGARTTYAARAGYGAYMGNGGNTGYGARATHAAYMGNATH YTNATHGARAAYAARGARTTYYTNGCNAAYTCNAARAARACNTAYTCNGARYTNGCNAAR CARATGAAYACNYTNAARGTNAAYATHGAYGGNTCNMGNCARMGNYTNGAYGARYTNAAR GARYTNMGNGARTCNGARGGNCCNATHYTNAAYGARGAYGGNGAYATHGTNATHAGYGAR GCNGARTTYAARGARATHACNAARYTNMGNGARYTNAARACNTCNTAYMGNAGYAARMGN GAYGARYTNGCNAARACNGARTCNGARGTNAARTAYTGYCARAARYTNGTNGAYCARTGY MGNYTNAARYTNATHCARGARTTYGAYAAYTGGTAYAGYGARAGYTTYYTNAGYGCNGCN GARGARGCNCARACNAGYYTNGGNGTNGGNAGYGGNGTNMGNCCNGGNGTNATGYTNCCN ATHACNAGYYTNACNAAYGARGAYGARCARGARAARTTYGARMGNYTNCARYTNGARYTN ATGATGAAYAAYGCNGARTCNGCNGCNTTYTAYAAYGCNCARATGMGNACNTCNMGNMGN AARATHTAYGGNGCNGCNYTNAAYCARCCNCARCCNGCNTTYMGNMGNCARGCNGGNACN CCNACNATGACNTTYMGNAAYCARCCNCCNGGNYTNATGCARATH--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNTCNTGYACNTTYCARTGGAGYATHTCNAAY TAYTCNAARAARYTNGARAAYGARAARAARGGNAARNNNACNAAYACNGTNTCNGARCCN TTYTAYATHGGNCAYTGYGGNTAYYTNGCNMGNYTNGARGTNTAYYTNAAYGGNAAYGAY ACNGGNTAYGAYMGNTGYATHTCNGTNTTYYTNMGNGTNATHAARGGNGARTAYGAYGAY YTNYTNCARTGGCCNGCNAARYTNTCNATHGCNTTYATHYTNATGGAYCAR--------- ---AGYGAYGGNTCNAARAGYTCNAARATGTAYAAYGCNGTNTTYGAYTAYGARCARCCN TCNGGNGAYTCNTTYAARGGNAGYACNTCNTGGGGNYTNGTNGARTTYGTNTCNCAYTCN GCNYTNCARGARAAYGTNTTYATHAARGAYGAYACNATH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MGNAAR------TTYCCNATGTAYYTNGTNGAY GCNTTYACNAARAARGCNYTNAGYGGNAAYCARGCNGCNATHTGYYTNGTNCCNTCNGAY GTNACNYTNTCNGARGAYGARATGCARAARATHGGNGCNGARATGAAYYTNTCNGARACN GCNTAYATHCAYGTNYTNGAYAARGAYGCNGAYTTYAARTCNGGNAAYAARTTYTCNYTN MGNTGGTTYACNCCNACNAARGARGTNAAYYTNTGYGGNCAYGCNACNYTNGCNTCNGCN GCNGTNYTNATHGAYGGNGTNGGNAAYGCNAAYMGNGTNATHGAYTTYTCNACNAARAGY GGNACNYTNTCNGTNAGYMGNCAYCCNGAYAARACNGGNTTYYTNTCNATGGAYTTYCCN AAYAAYAARCCNGTNCCNCARGAYACNGARAARATGGARAARYTNATGYTNAGYYTNGTN AGYGAYYTNGAYATGATHCARGARGTNCARTAYTCN---GCNACNACNAARAARYTNGTN GTNMGNYTNAARGAYCAYATHCAYMGNAARGARYTNGARMGNYTNAGYCCNAARGCNAAY GTNYTNATGGARGCNGARCARTCNGGNATGGTNATGGGNGTNGGNGTNACNYTNAARGGN TGYCAYGCNAAYGGNTGYGTNGAYGARGARGGNAAYYTNTAYGAYTTYYTNTCNMGNTAY TTYGCNCCNTGGAAYGGNATHCCNGARGAYCCNGTNACNGGNTCNTGGCAYACNGTNATH GGNCCNTAYTGGGCNACNGARYTNGGNAARACNATGYTNTAYGCNMGNCARTGYTCNCCN MGNGGNGGNGAYYTNTGYGTNGARGTNAARGAYGARMGNGTNATHYTNATGGGNCARTCN GTNATHACNYTNGARGGNACNTTYCARYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNCAYAAYGCNGAYGAYGAYGARATGMGNTTYACNGGNYTNCAYGGNAARTCNGAYATH CCNTCNMGNACNTTYGAYMGNYTNAARAARTCNACNCCNGARGAR--------------- ---AAYGGNCARGAYAAYCCNCAYATHGARGAYGARTCNGAYMGNGTNGGNAAYTAYAAY GARGCNTCNATHMGNTAYACNGGNAARAGYATHCCNTCNCCNGCNTTYMGNGTNYTNCAR ACNTGGGCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATHCAYGGNGAYGTNAARCCNGAYAAYTTYYTNYTN ATGGAYYTNCCNYTNGTNTGYAAYAGYCARAARCCNYTNGARGTNTTYGGNCCNCARYTN MGNGTNTTYTGYYTNACNGAYTTYGGNCARACNATHGAYATGCAYATGTTYCCNTCNGGN ACNTCNTTYMGNACNAARACNAAYACNGAYGGNTTYGARTGYATHGARATGMGNACNGAY MGNCCNTGGACNTAYCARGCNGAYYTNTTYGGNYTNGCNGGNACNGTNCAYGTNYTNYTN TTYGGNTCNTAYATGAARGTNTTYGTNGARAARGGNGTNTGGAARATHACNGGNAAYTTY GTNMGNAARTGGAAYGTNTCNYTNTGGAARAARYTNTTY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TGYYTNGARGCNTCNGAYTCNTCNGAYCARGAYYTNACNAAR TTYTTYCCNCARGTNAAYAARTTYATHCAYAARGCNMGNYTNGARGGNGGNGGNGTNYTN GTNCAYTGYYTNGCNGGNGTNTCNMGNAGYGTNACNGTNACNGCNGCNTAYATHATGACN GTNACNGARYTNGGNTGGMGNGAYGCNYTNAAYTCNATHMGNGGNGCNMGNAGYGTNGCN AAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TGGGTNAAYGAYGARMGNGTNTCNYTNGCNCARYTN CARACNCARCARGCNGGNTGYTAYAAYMGNMGNCCNMGNAGYTTYTCNYTNGGNMGNCAY AAYCAYAAYYTNCARGAYCAYTTYACNAAYATHATHAARMGNTCNTTYMGNTTYGCNACN AAYGAYGARAARTCNYTNCARGTNTCNGARTAYATGGCNGARAGYYTNTGGTCNTAYGAR ATGCCNGTNAARYTNYTNAARYTNTGGGTNACNGARGARAARATGATGGTNAARATHYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TGGGARGGNGTNTCNMGNACNACNAARAAYGCNGGNGARGCNGAYGCNGTN GGNATGGTNGTNYTNTTYCAYGAYCCNCARACNGAYYTNCARAGYATHATHYTNATHMGN CARTAYMGNCCNCCNATGGARACNTGYACNATHGARTTYCCNGCNGGNYTNATHGAYAAR GGNGARACNGCNGGNGARGCNGCNGTNMGNGARATGAARGARGARACNGGNTAYGAYGTN ACNGTNGTNGAYGTNTCNCCNGCNACNTCNYTNGAYCCNGGNGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ACNAARAAY YTNTCNAARYTNCARATHYTNYTNGTNGARYTNCARACNMGNTAYAGYGAYTGGCARGCN GGNGGNYTNTCNACNCCNTAYTTYCAYAARCARYTNAARTCNTCNGARGCNYTNYTNTCN CARTAYGARGARAGYGCNGTNCCNTCNGGNTGGYTNTGYCARTGGGAYMGNGCNAGYTGY MGNTAYTTYTAYMGNAAYGARCAYACNGGNCAYACNCARTGGGARTAYCCNCARGCNTCN TCNAARGGNGGNGARGTNAARGAYTCNGGNAGYAGYMGNGGNMGNAGYAGYAARAARMGN MGNAGYAARGAYGCNGARGARMGNGGNGARGARAGYAAYAARACNAGYAGYMGNAGYCAY MGNAARGCNTCNGARAARGAYMGN------------------GGNAARMGNGAYMGNCAY AGYGGNAGYTCNCAYCAYCAYMGNAARAARAARMGNMGNMGNMGNGARCAYAAYAGYAGY AGYAGYAGYAGYAGYGARGAYGARAGYGGNTCNTCNMGNCAYMGNCAYMGNAGYAARMGN AARAARMGNGGNMGNTCNGAYAARTCNGCNAGYYTNGARGTNATHGAYTGYGAYGGNCCN GAYGAYGTNCARYTNATHGARGAYAGYCCNCCNCCNGAYGARTCNMGNGARTAYMGNAAR AAYAGYYTNGAYAAYGAYGGNGGNAAYACNGCNTCNGTNCARTCNGTNTCNGCNACNYTN GGNYTNATHGCNGAYTAYGGNTCNGARCARGARAARMGNGARATGGARGARGARYTNGAR GGNATHGAYGGNGARGARATGGARAARGARGARGARGARGCNGCNGGNGGNATGCARGAR GAYGARATGAARGARGARGAR------GARCCNGGNGARGARGARGARGARGARGGNGTN ---AAYAAYGCNGTNATHGTNAARCCNCCNCARATHATHGTNCCNCCNTAYGTNGCNGCN ATGAAYCARCCNCARYTNTAYTCNGCNCCNGCNYTNTAYGCNTCNGCNCCNGTNCCNTCN TCNGARACNGCNTCNGCNYTNGCNATHACNAGYACNAGYCARGCNTCNGARGARAAYGAY AARGCNGCNAGYAARAARAARAARAARGAY------------AARTCNGGNACNGCNAAY TCNAGYATHATGATGAARAARAARMGNGTNTCNTCNATGGTNCARAARTGGCARCARGTN AARAARGARGTNGARAARGARAAYMGNGAYAARGARYTNAARCARGCNGCNATHMGNGAR AARATHAAYCARYTNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNYTNATHGGNGGNTAYAARTTYGAYATH MGNATHTAYGTNGTNATHCCNAGYTTYCAYCCNYTNCARGTNTAYATHCAYGARGARGGN YTNGTNMGNTTYAGYACNGARAARTAYGAYYTNMGNMGNYTNGAYAAYGTNTTYGCNCAY YTNACNAAYACNAGYATHAAYAARTTYAGYCCNGGNTAYACNGCNGAYAARGARGARGTN GGNCAYGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ACNGCNGTNACNTGY YTNGAYMGNGGNAARGTNTCNTCNTTYGTNCARCAYMGNGGNTCNGTNCCNYTNTTYTGG TCNCARGAYATHTCNAARATGGTNCCNAARCCNCCNATHTCNYTNGAYCARMGNGAYCCN TAYTGYAGYGCNGCNGGNATGCAYTTYAAYGARATGYTNCAYMGNTAYGGNTCNCCNATH ATHGTNTTYAAYYTNGTNAARACNMGNGARAARAARMGNCAYGARAGYATHYTNAGYGAR GAYTAYGTNCAYACNATHGAYTAYYTNAAYCARTTYYTNCCNTCNGARCAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARYTNCARAARCAYCARGARTCNYTNMGNAARYTNCARCARGCNCARAARGAR CARYTNGCNAAYATGCARYTNCCNGCNTCNAGYAAYTGGGCNAARCAYGCNTCN---CAR GGNAGYGTNAGYCAYTCNAARTCNYTNACNGARATHCARGARGARGARGCNMGNMGNGAR AARGARMGNCARAARGARCARCAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MGNGCNAAY TAYTTYTAYTGYGTNMGNGTNACNGAYCCNGARATHCAYAARAAYATHACNAAYGCNYTN GAYTGGATHGTNGAYAARGARCCNCARTTYGCNGAYTTYTGYTAYACNCCNGARATGYTN CAYGTNACNYTNGCNGARGTNTCNYTNCARAGYGARGARGAYATHAARYTNGCNTCNCAR GTNYTNCARGAYTGYMGNACNAARYTNCARGARATHATHCCNAAYTCNCCNYTNGTNTTY MGNGGNATHTCNGAYTTYCAYAARAARGTNATGATHTCNAARGTNAAYTAYGARGAYGAY TTYGTNACNTTYGCNGAYTGYYTNMGNTCNCARGCNAARGARGCNGGNGTNAAYGTNGTN GARAAYCAYGARTTYACNCCNCAYATGACNATHYTNAARGTNAARCCNATHAAYCCNGAY GCNGGNAARTTYAAYTAYCARGARCARMGNAARCARYTNGCNGARGARMGNMGNMGNGAR TAYAAYCARATGYTNCARCARAARTCNAAYCCNMGNACNMGNGARMGNGARCCNGARATH GAYAAYCCNTCNATHATHCCNTTYAAYMGNCCNGAYCARGARMGNATGAARGTNAARATH YTNGARGARGARMGNCARMGNGARTAYAAYGARACNYTNGCNAARATGCARGAYMGNCCN MGNAARMGNGARGTNACNCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGCARGCNTAYAGYCCNCCNYTNTCNYTN TGGAAYYTNGTNGARCARCAYGTNCCNACNTTYGARYTNGARGARGTNAARAGYATHYTN GGNTCNAAYYTNGTNGAYCARAGYYTNGARYTNCAYAGYGARATHGARATGYTNYTNGAY ATHTGGMGNGAYATGMGNGAYGARGTNCARGARAAYAARYTNGTNCARTCNMGNYTNCCN GARCCNCCNAAYCARMGNGARMGNYTNATHCARGARATHAAYTTYTTYGCNGARAAYATH AARGAYAARGCNMGNCARAARGGNATHGAYCCNGARAAYATHYTNAARACNCAYAAYAGY AAYGTNATHGAYTAYGCNTCNGAYGCNAGYMGNCCNGGNTCNTCNATHGGNMGNACNTCN MGNTCNTCNGAYGGNMGNGARACNCCNATGATGGTNGCNTCNCCNGAYMGNATHYTNAAR GCNTAYGARGTNACNGAYGARATHGARGCNTGYAGYGGNCARYTNAAYGTNGAYMGNTTY GAYAAYGTNTGYGCNCAYYTNMGNYTNACNYTNGARAARGARGTNGAYCARYTNYTNGGN GAYATHGARTTYYTNCARAAYTGYYTNGAYAAYCARGCNAAYATHMGNGAYTCNATHGAY ACNCCNMGNATGTCNMGNGARCCNACNYTNACNGARYTNMGNGARGARMGNACNTCNYTN GARAARGARYTNYTNYTNACNGAYAAYYTNACNTAYACNCCNCARGTNGGNAARCCNYTN TTYAAYAAYYTNATGAARCCNYTNYTNTCNAAYCCNATGAGYACNTCNACNCCNGTNACN MGNTCNAARCARACNCCNGTNAARGCNTTYCAYAAYAGYGCNATGGCNACNGARYTNTGY AAYAARGCNAAYGARGARTAYGTNGARGARAAYTAYCARAARGCNATHGAYYTNTAYACN GARGCNYTNGCNYTNGARAAYACNMGNGAYGAYATHTAYTGYTTYMGNGCNCARGCNAAR YTNTCNYTNGGNCAYTCNTCNGAYGCNATHAARGAYTTYGAYGARGCNYTNMGNYTNAAY CCNAAYAAYCARAARGCNTAYATHAARAARGGNTCNGTNYTNYTNCARATGGGNGARGTN YTNCARGCNCAYGGNGTNTTYAARGARGGNCARAARCAYTGY---GGNGAYAARGAYTTY GARGAYTGGYTNGGNAARGTNGARTGYMGNATGAARGARYTNGGNATHAGYCARTCNTCN CARGTNACNACNGARCCNGCNGARGTN------------------CCNTCNATHAARTAY AAYTGGTAYCARACNCAYACNCAYGTNATHGTNACNGCNYTNGTNAARAAYGTNAARAAR GARGARYTNGTNYTNGAYGTNGARGAYMGNTCNYTNMGNATHAGYATHCARMGNGGNGAY CARTCNAGY---GAYYTNAAYATHATHYTNGCNCAYTGYGTNGTNCCNGARCARACNCAR TCNAARYTNTTYTCNACNAARATHGARATHAARYTNAARAARTCNGARGGNATHCARTGG GCNAARYTNGARGGNTCNCCNAAYGARGTNGAYAAYAGYGTNYTNCCNGCNTGYGCNGCN CCNGTN---AAYGCNGARGCNCCNMGNTAYCCNAGYTCNTCNCAYCAYTCNMGNGAYTGG GAYAARYTNGCNGCNGARGTNACNGARGARGARAARAAYGARAARYTNGARGGNGAYGCN GCNYTNAAYCARTTYTTYCARAARATHTAYGCNGAYGCNTCNGAYGAYACNAARAARGCN ATGATGAARTCNTTYTCNGARTCNGGNGGNACNGTNYTNAGYACNAAYTGGGAYGARGTN GGNAGYAARAARGTNGARGTNAARCCNCCNGAYGGNATGGARTAYAARAARTGGGAR--- ------------------------------------------------------------ GARGARGCNTCNACNGCNTCNCCNAARAARGCNGARCCNGAR------CCNAARAARCCN ACNACNGTNAARGGNMGNGGNMGNCCNCCNYTNTCNGCNGARGARAARGCNAARMGNGCN GCNAAYAARAARCCNAGY---GGNMGNGGNMGNGGNMGNCCNAARGGNTCNACNAARGCN TCNAARAGYAARAARGTNATHAAYGAYMGNGTNAAYGCNGGNTAYATHAARMGNAARGAR YTNTTYGTNACNTCNAARGTNCCNMGNGTNMGNATGGTNACNGGNGAYGTNATGCAYTCN GGNYTNCARTCNYTNGARAARYTNAARYTNCARCAYYTNGAYATGYTNYTNYTNCAYAGY GCNTGGAAYMGNCCNYTNAAYATHGTNGAYGTNTGGMGNGCNYTNGARTCNATGTGYAAY GAYGGNYTNGTNTCNAAYATHGGNGTNTCNAAYTTYACNGCNGARCARATHGAYAARGTN YTNAARATHCARAARGTNCCNYTNTCNAAYGTNCARYTNGARAGYCAYATHTAYTAYCAR CARNNNAARATHAARCARYTNTGYGAYAARAAYAAYGTNGTNATHTCNGCNTAYGCNCCN YTNGGNGCNCCNGCNMGNCCNAGYCARCAYGTNACNGGNACNTCNTCNYTNYTNGARGAY CCNGTNATHYTNCARATGTGYGARMGNTAYAARAARACNCCNGCNCARGTNATGYTNAAY TTYYTNGTNAARAAYGGNATGGTNGTNYTNCCNAARAGYTCNAAYAARGARMGNYTNCAR GARAAYYTNCAYAGYYTNGAYTGGTCNYTNAGYGARAGYGAYTTYAARGCNATHCARGGN YTNGAYMGNGGNATHAARYTNTTYGARTTYGTNTAYATHAARGGNCAYCCNGAYTTYTTY CCNGGNAGYGARTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ AARYTNYTNAGYGTNAARACNCCNATHGTNGARGCNGAYAARATHMGNACNYTNGCNTGY AARGCNYTNGCNGGNATGTCNMGNTCNGARACNATHMGNCARATHATHGGNAARMGNCCN CCNYTNAAYAAYGGNCARYTNCARTCNYTNGTNAARGARCCNGTNYTNGCNGAYAARMGN ACNGTNCAYYTNYTNTTYTGYAARTAYGCNTCNACNYTNYTNGARAARATHGCNGGNAAR GAYACNAGYGTNTTYGGNGCNACNACNYTNGARGARATHMGNMGNGCNGGNGTNGTNGCN CARACNAARATHGTNTAYCARGAYMGNGARYTNYTNCARYTNATHCAYGARCAYYTNACN TCNAARGGNYTNCAYGAYACNGCNTCNGCNYTNCARAARGARGCNAGYYTNCCNAARTGY TCNACNCCNCCNCCNCAYCCNTTYACNTGYACNCCNAARGCNMGNMGNCARYTNAGYCAR CCNAAYGGNCCNAGYGTNTCNTCNCARAGYCCNACNCCNAGYGGNACNCCNGCNTCNCAR CAYCAYACNGGNCCNATHAARTTYAGYYTNAGYMGNACNCCNGCNACNAGYAAYACNCCN CARACNAGYYTNCARAARTCNACNAARMGNMGNTTYGARGGNATHATHCCNCCNGGNYTN CARCARMGNTCNAGYGGNAGYGARTAYGARGTNTCNYTNGAYAARATHGTNACNGARTAY YTNMGNAARCARCAYGCNYTNTGYCCNCARCCNATHTCNACNTGYCCNACNATGTCNYTN TTYYTNCCNCAYCARTGYCCNGARCCNYTNGGNAARGAYAGYGCNTCNGTNTCNATHGCN AGYMGNYTNTTYGAYMGNCARATGMGNCCNCCNCAYGGNGGNCCNAAYGGNCARMGNYTN AAYMGNMGNTAYYTNTAYTCNAARATGGCNYTNYTNACNAGYTAYMGNGAYGTNTCNAGY GAYGGNYTNGCNTGYTGYGCNTTYGAYTGYGGNGGNGAYACNYTNTTYGTNGGNTCNTTY GCNGGNGARYTNMGNGCNATGCCNGTNAAYTCNGCNAAYGAYGAYTAYGTNAGYTCNATH TGYCAYTCNTCNCCNGTNATHCARATHAAYACNTCNATGGTNGAYCCNGAYYTNATHATH ACNAGYACNTGGGGNGCNTCNCARAAYTGYGCNYTNTGGAAYTTYAARMGNGAYACNGAY ACNTGYGTNYTNAARTAYMGNTTYGAYGARCAYCAYGCNTCNYTNGCNAAYYTNAGYCAY GAYMGNTTYATHGGNACNAARGAYTTYGTNGCNACNATHTAYGAYACNGCNGCNGGNACN AARGTNCARACNYTNTAYGAYGARAGYAARGCNAAYAAYTAYAARTTYAAYGTNGCNTCN TTYAAYCCNACNGAYGAYYTNGTNYTNAAYGAYGGNAAYYTNTGGGAYGTNMGNTCNAAY AARYTNATHTAYAARTTYGAYAARTTYAAYCARTAYACNAGYGGNTGYTTYCAYCCNMGN GGNYTNGARGTNGTNATHAAYTCNGARATHTGGGAYATHMGNACNTTYMGNYTNYTNCAY ACNGTNCCNGCNYTNGAYCARTGYCARATHYTNTTYAAYCAYGGNGGNGAYGTNATHTAY GCNATHMGNGTNGAYGAYGARYTNTCNGGNGAYATHATHATGMGNMGNGAYTAYGCNTCN ACNYTNACNACNTTYGAYGCNYTNAAYTAYACNAGYATHGGNACNTTYGAYYTNAARACN AAYAGYATHYTNGAYYTNGCNGTNGAYMGNAAYGAYCARTTYATHGGNGTNATHGARAAY ATGTCNCARCAYGARTCNGAYCCNGARGARTCNATHTGYMGNGTNTAYGARATGGGNAAR YTNMGNATGCCNGARGAYCARGCNGAYGARGARGARGAYAAYGGNCARAAYAAYGAYGAR GAYTAYGAYGAYGAYGAYGAYGAYGAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATHGCNCCNAARACNTCNCCN TGYCCNAARTCNGTNCCNTAYGTNCCNYTNCCNMGNATGAGYCCNAARMGNAARGARYTN AAYMGNCARGTNMGNCAYATHYTNCCNAARTCNTTYGTNTTYGARTCNAARTCNCCNTCN CCNACNAARACNACNGCNYTNAAYYTNAARAARAARGCNACNYTNYTNTGYCARAARAGY CCNGTNAARATHYTNCCNMGNCCNGCNAGYATHCCNGTNGCNGAYATHGGNATGMGNACN MGNAGYMGNTCNTCNATGYTNACNMGNTCNCARMGNGGN------------ATHTCNAAR CCNAARMGNAARGARGARCCNTCNCAYAARGARYTNAAR--------------------- ---MGNGTNAARAARACNGARGARGAYTAYGARAGYGCNAARGARACNGARAGYGARGCN AGYGARTTYGARGARTCNGGNYTNTCNCARGARGARGAYGAR------GAYMGNACNAAR YTNGAYGAYYTNATGGCNGCNAGYACNACNATHMGNTTYGGNTCNAARCARYTNGCNACN ACNGAYGAYGAYGTNAARACNAARGCNGARAARAARAARGCNATGTCNYTNTCNYTNYTN CARCCNGAYYTNGTNCARAAYGAYCCNAARAARGAYGAYMGNGAYACNGCNTTYGCNCAR CARTAYTTYAAYCARGTNAARAARACNYTNTCNTCNGAYCCNGARMGNTTYTAYAARTTY YTNTCNYTNYTNAARGAYYTNAAYAARGAYCAYACNAGYCCNGTNGARYTNTAYYTNGAY ATGGTNYTNYTNYTNTCNGAYCAYCARCARYTNGTNGAYGAYTTYGCNGGNTTYYTNYTN TCNTTYCARGCNGTNGARTGYCARTGYTTYTCNACNAAYTTYCARTAYGCNCARATHMGN CARTTYYTNMGNCARGTNGARGTNCAYTGYGGNTCNTCNACNACN---ACNTAYMGNAAR GTNYTNAARGCNYTNTCNACNTGGAGYAGYATGTGYCARGARGGNAARYTNGARGGNAGY YTNMGNGARAARATGYTNACNATHYTNAARAAYGTNCCNGGNGTNYTNGAYAGYYTNATH GGNTAYTTYYTNGAYGGNGCNGTNTCNGAYTGYCAYGCNATGGAYTTYGARGAYGTNTGY YTNGAYGARGARATGGARAARGGNGARGGN------GAYTTYGARAAYATHGTNYTNCCN GAYGARCCNGARGAYTAYAAYACNAARACNTGYTCNTGYCARTGYCAYAGYAGYAAYCCN CARGAYGAYMGNTAYCARMGNMGNATHAARCAYTGYGTNTCNTGYAGYYTNCARGTNTAY GAYGGNCARCCNGTNYTNAARYTNTCNMGNTAYGARTCNMGNCCNATGTCNATHGTNTAY TCN---------TCNGARGARAARGARAARTGYGCNCARGCNAARATHGARGCNGCNCAR ATHGTNYTNGCNAARGCNAARGTNCAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AARGTNAARTCNTTYAARMGN AARTAYCCNGAYYTNTAYMGNMGNGTNTGYGAYAARGARGARAARGAYTTYYTNMGNGAR AARGGNGTNGTNTCNGARACNCARTCNGAYYTNGGNYTNACNGCNYTNMGNAGYGARGAR GTNTAYGAYYTNATGATGAARGAYTAYAAYGAYMGNTAYCARGARTAYYTNACNGTNYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATHGGNCCNGCNTTY CCNGGNTTYGAYTAYAAYTCNMGNAARGGNGTNAGYGCNGTNCCNATHATGTAYCARAAY YTNGARGTNCARGCNTAYTCNGARGGNGGNGGNTAYTTYYTNCCN---TAYAGYCARCCN TCNTAYGARACNCAYACNGTNYTNGGNCARTAYAARACNYTNGARAGYTTYCCNGCNGCN ATHGTNAARTGY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATGGCNAARMGNGGNCCNCARTCNGARYTNAAYGAYMGNAAYTGGGAYGAYGAR GARGARGTNGARGARGCNGGNGTNTTYAARCARGCNTCNTCNGAYACNYTNCARAGYMGN GTNATHAARAARGCNAARMGNMGNGGNGGNGGNGARGARGGNGGNAARTCNGGNGCNTTY GGNGGNTTYGGNGGNYTN---------TCNAARGCNACNCCNACNGCNGCNTCNCCNATG ACNGGNYTNGGNGGNAARACNTCNACNGARAAYAARCCNTTYAGYMGNGGNGCNGCNACN TCNGAYAAYAAYGTNGARTCNACNACNMGNAARAAYGAYTCNACNGCNAARGAYAAYTCN TCNTAYYTNCAYTCNYTNAARGCNYTNAAYGARAGYGTNYTNGCNTGGATHAARCARCAY GTNGAYAARAAYCCNTAYATHATHYTNACNCCNATHTTYAARGAYTAYGAYAARTAYGTN GCNAGYYTNGARGCNAARAARACNACNGCNTCNACNAAY---GGNTCNGTNTCNMGNGAY AARGAYAARAAYACNGARATGGCNGCNAARGGNCCNACNTTYACNTTYGGNTCNGCNTCN ---------------GCNTCNAAYGGNGAYGGNTTYAARTTYTCNACNGCNATHGCNACN ACNAAYTCNGGNTTYAGYTTYGGNAARACNGCNGCNCCNTCNATHTCNTCNGGNTTYTCN TTYGGNCARAGYAGYTCNGCNTCNAARTCNYTNGCNACNGCNACN---------GCNACN ACNGCNGCNTCNACNGGNTTYTCNTTYGGNAGYAGYACNAGYAGYGCNGCNTCNACNACN GCNACN---------------------------GCN------------GCNCCNTTYGGN ------------------GCNTCNGGNTTYTCNTTYGGNGCNYTNGCNGCNGCNAARGTN GCNTCNGAYAARGCNCARGCNGARGGNGGN---------GGNGGNGAYGAYGAYGARTAY GTNCCNCCNAARCCNGARGTNAARGARATHAARGARGARGGNTCNYTNTAYTCNAARMGN TGYAARYTNTTYTAYCARAARGARGGNGGNTGGGTNGARMGNGGNGTNGGNAAYGTNCAY GTNAARCCNYTNGAYGARCCNAARACNCARYTNYTNATHMGNGCNGAYACNAAYYTNGGN AAYATHYTNYTNAAYATHAAYYTNACNTCNGCNYTNCCNGTNTCNMGNCARGGNAARAAY AAYGTNYTNYTNGTNTGYGTNCCNAAYCCNCCNYTN------------AARGARGGNTCN ACNGAYCARACNCCNATHTCNATGYTNATHMGNGTNAARACNGCNGCNGARGCNGAYGAR YTNYTNGCNAARYTNGARGARMGNAARGCNYTNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNATHGARCARATHGCNTTYMGNACNGTNGGN YTNYTNTCNACNGTNAARGTNTGGTCNYTNYTNGARGCNMGNYTNGARGTNMGNAAYATG CAYGAYGCNACNGAYGCNACNGCNCARAGYTTYACNCARATHATHATHTCNCCNCAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GCNGGNGTNGCNTCNATHYTNTCNGTNYTN YTNAARCCNTCNCAYCCNAAYYTNATGTGYTTYGCNTTYTCNCCNCCNGGNGGNYTNATG AGYCCNTCNGCNAGYMGNTAYACNCARGAYTTYATHTGYTCNGTNGTNYTNGGNAARGAY YTNGTNCCNMGNYTNGGNATGTAYACNYTNYTNGAYYTNAARGTNAARATHYTNMGNGCN YTNTGYCARTGYGAYAARCCNAARTAYCARATHYTNGCNTCNGGNTGYTTYMGNYTNYTN TGYTGYAARGGNTCNCARGARTCNGAYTCNGCN---------YTNAGYYTNGTNCCNMGN TAYGTNCARGAYCARAAYTGYATHATHGARGAYYTNTTYGTNCARGAYGCNYTNMGNYTN GCNGARAAYAARATGGARGARATHYTNCAYACNGARTGGCCNYTNCAYCCNGCNGGNCAR ATHYTNCAYATHATGGAYATHAAYGGNGAYACNGTNTGYGGNGGNGAYCCNCARTTYTGY GCNGTNTGGTCNAGYCCNGARTAYTTYGAYAARATHGTNATHAGYCAYAARATGGTNAAR CCNGTNAARGGNAGYGTNAARATHCCNTCNCCNTTYACNCCNATGGCNCCNTAYGAYGAY ATGAAYACNCCNGARYTNAARAARGCNGTNACNAARGTNGGNGTNMGNCCNATGGGNAAR AARMGNATGMGNGAYYTNYTNAARCAYATHTAYACNGARACNCAYCARTAYGARACNGAY TCNGGNGAYGGNGAYACNCCNYTNAARCCNCCNAAYCCNAAYGTNCCN------------ ---TTYAARGARGCNCCN------------AARTAYAARGARGTNTCNAARAARCARYTN TTYACNAARTCNTCNTCNGGNACNMGNATHTGYCCNAAYGTNCARAGYACNAGYAARGGN ACNGCNATHTCNTCNAAYGAYAARTGYGGNAARATGGARACNYTNGARAARACNAARGCN TGGGTNGARAARATHCARAAYTTYCCNACNYTNTCNTCNGAYGARCARGTNGAYGGN--- ------------------------------------------------------------ ------------------GARGARGAYGTNYTNAGYTCNCARGAYTCNAGYTTYAGYGAY GGNCCNGAYGTNCCNGARGARAGYATHYTNCARGTNYTNCCNGAYGARGARGARACNGAR GCNCCNTGYACNCARYTNTCNCARACNAGYYTNGARGTNGTNAAYGGNMGNYTNATGGCN TTYYTNMGNGAYAAYCCNAARATHTAYGARCARATHYTNATGTAYGARGCNYTNGARYTN GAYGTNYTNAARAARAARATHGCNGAYGCNGGNATHMGNGTNGGNTTYTCNMGNYTNCAR GAYTTYYTNGAYGARMGNTGYGTNACNTTYTCNATGAARAAYATHAGYAAYMGNAAYTTY MGNCAYTTYCARAARAARAARAARGGNAAYTCNCCNACNAARMGNAARAARACNACNCAY ATHTCNAAYACN------TCNYTNGTNGAYATGMGNGTNAARYTNGAYGGNTGGTTYGGN ACNYTNAARGAYAAYATHYTNGGNGARYTNAAYTCNTCNYTNATGGCNGTNYTNMGNACN CARCAYGARGCNAAYYTNMGNTCNAAYGARGARATHCARGCNGARAARGGNGCNYTNCAR AARGARGTNAAYCARYTNACNGARCARATGAAYAGYYTNGARCAYAGYTCNAARCARAAR TGYACNYTNATHAARAAYYTNACNGAYTCNYTNGTNGCNCARAARAARAARGTNGARATG GCNAARCAYTTYTAYCAYTGGAARGCNGAYCAYTAYGAYAARCARMGNGARATGTTYACN GARAARYTNGCNGTNCARCAYCAYGARMGNAARYTNAAYYTNMGNGTNYTNAARGCNTGG TAYGGNATGATHCARACNMGNTGGMGNTCNMGNACNGARMGNAARAGYCARACNCARGCN AARGARATGTGYATGAGYYTNAGYAGYGAYTAYGARGTNAARGTNGGNATGYTNAAYGAR AARGTNGCNGCNYTNGARNNNAARGTNTCNYTNYTNCARGCNGARMGNGARATGTAYTCN GARCARGTNAARAARGCNTTYATGMGNGGNATGTGYGCNYTNAAYACNGARACNATGTCN GTNTTYGGNGAYGAYCARCCNGARTCNACNATHGAYGTNATHCARGARGTN------TCN ACNTTYGAYACNAAYACNYTNGTNACNAGYYTNGARGARATGGAYAGYCAR--------- ---------------------CCNAARTCNATHCCNCAYACNGTNGARAARAGYTCNTCN CARTCNCAYTCNTCNYTNTCNCCNACNMGNACNGGNGARAGYCARTCNYTNCCN---ATG CARGGNYTNATGCARCAYCAYTCNCCNATHATHTGYGGNGCNGCNACNAARCCNAARTCN ACNAARAGYAAR---------------CCNAARTCNAGYAARACNMGNTGYAAYAAYAAY AARGTNGTNTCNTCNTCNCARGTNYTNGCNCCNCCNATGGCNTCNGTNGTNGTNGARMGN CAYCCNCCNGTNAAYAARCARACNGTNGGNAARGCNACNGCNATGMGNTAYCCNAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGAGYTCN GAYACNTGYTTYAARTGYGGNGGNMGNGGNCAYTTYGCNMGNTAYTGY------GGNGTN GGNGGNGAYGGNCCN---GGNMGN---------------------------------GGN TTYTGYGGNCARAARTGYTAYAARTGYAAYMGNATGGGNCAYTTYGCNMGNGARTGYACN CARAAYCARGARMGNTGYTAYAARTGYAAYGGNYTNGGNCAYATHGCNAARGAYTGYGAR AARCARATHTCN---ACNGGNGCNTGYTAYAAYTGYGGNAGYAGYGARCAYYTNCARMGN GAYTGYCCNGAYGCNATHGTNAARTCNTGYTTYMGNTGYGGNGAYACNGGNCAYGTNGCN AARGARTGYCCNGGNAARCCNTTY------------GCN------------GAYGAYMGN AARTGYTAYACNTGYGGNGGNATHGGNCAYGTNGCNATHCAYTGYCCN------------ TCNCCNMGNAARGARTGYTAYMGNTGYAARCARACNGGNCAYATHCARAARGAYTGYCCN ---ATH---GARAGYGAYACNYTNTGYTAYAAYTGYAAYAARGTNGGNCAYATHGCNMGN GAYTGY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AARGTNGCNMGNMGNGARATH GGNGTNYTNACNTCNAGYMGNAAYGTNCCNMGNCCNATGGGNATGAARAAYGGNATHATG TAYCCNGAYCARACNGARMGNCCNATHAARTAYACNMGNAARCARATHGAYTAYTCNATH YTNGAYGAYATHGGNCAYGGNGTNMGNTCNCARAGYCARCARGCNACNACNCCNMGNACN GTNMGNTCNCCNTCNGTNAGYAGYACN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNCCNACNCCNCCNCCNCCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNMGNACNTTYGCNTCNTTYAARGARTTYGAR GARGAYTTYGCNATHTTYCARTCNGTNAAYCAYGTNGTNTTYTGYAARAARGCNTCNMGN AARYTNCCNACNTTYCAYCCNCARAGYGARAARYTNGTNTAYCARTTYGTNCAYTAYGCN TGYAARCARGGNMGNAARMGNAAR---TCNGARAGYAARGGNYTNMGNCCNAAYCARAAR TCNYTNAARTGYGAYTGYAARGCNTAYATHMGNYTNTCNGCNGTNGARGGNGAR---GAR TGGAARATGAARATHAGYGGNAGYAGYCAYGTNCAYTCNAAYCAYCCNGTNGAYGCNMGN ACNGCNGCNATHTAYCCNGARAAYMGNMGNGCNATHYTNACNGARACNGTNMGNGTNATG GCNYTNAGYGARGTNCCNAARAARACNYTNAARAARTAYATHGARGAYAGYCARGGNGTN CAYATGMGNTCNCAYGAYGTNTCNAAYYTNMGNMGNMGNATG------ATHGTNGTNCAY MGNYTNMGNCCNTTYGCN---YTNGGNYTNTAYGCNAARGCNGGNAARTCNATHCAYACN ACNCCNMGNAARTAYGGNGARGCNYTNTAYMGNGARAARATG------TTYGAYTAYAAR GARCCNAARTAYATHCARCAYGGNGGNACNGCNTTYAGYGCNTTYATGTGGTAYTGGATH YTNTAYCAYTGYTAYTTYGARTAYGGNCAYYTNGTN------------------------ ---------------------ATGCCNGGNGARGARCARGTNGTNTTYYTNAAYAARYTN GGNGARATHCCNGTNYTNAAYGAYAGYTGGTTYGCNGCNGCNGAYTAYTAYTCNMGNGTN AARGAYTAYAAYGCNYTNATGMGNATGACNYTNTCNGTNGCNGARTCNGGNGTNAARGTN GCNGGNCAYYTNTCNACNCCNGTNATHAAYMGNTGYCARCCNCARATHAAYAAYYTNAAY GAYTTYGCNTGYAARACNYTNGAYGAYYTNGARACNAARTAYCCNGCNATHAARCARCCN ACNGARCARTGGAARGARACNTGYGCNGAYTTYGTNGARCCNGTNGTNGGNMGNGTNAAR CCNGTNATHTCNCARGTNCARGGNATHGTNGAYAAYGGNAARCARMGNATHAAYAGYATH AARAGYGCNAGYACNAAYATGATHGARGGNGCNAARACNMGNGGNGTNGGNACNGTNACN CAYGTNGTNAAYACNACNTTYGARACNGCNCCNGGNMGNTTYGTNACNMGNACNGTNGAY AGYGCNYTNGAYGTNGCNGAYAAYYTNGTNGAYAARTAYYTNCCNGAR------------ ---------------GARAARGARGARACNGAYGARCARCARGAYGARAARGARTCNACN ACNGCNCARTCNGARGTNGARAAYATGGARGARATGGAYCCNACNCCNMGNMGNGTNYTN GTNCAYGCNGGNTGYGTNACNGAYAARATHMGNAARMGNATGTAYMGNMGNGCNATGAAR GAYATHACNTAYGCNMGNGCNMGNACNTCNGCNGCNYTNMGNAARATGACNAGYACNGTN GARYTNATGGAYYTNGCNAARACNAAYYTNAAYACNACNAARGARAARGTNGAYCARYTN TGGACNGAYATHGTNAARGAYACNAAYGCNGCNGAYGAYAAR------------ACNGTN TAYGTNGGNACNGTNGARGAYMGNATHGTNGCNYTNGGNMGNATHYTNGCNMGNCARGTN MGNTCNGGNGTNACNGCNTTYGARAARGCNTAYTCNGARYTNGGNGARTTYAGYAARGAY CCNATHTCNAARTCNAAYGARTAYAARGAYYTNATHACNACNTTYYTNTCNGTNGARTCN ATHAARAAYATGACNTCNCARAAYYTNCARMGNGCNAARGARTCNYTNAARTAYYTNCAR GAYMGNYTNAARAAYATG---------GTNCCNTCNYTNAGYTGGATGACNGTNGAYATH AAYATGGARGAYATHCCNATHAGYGARACNGAYYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNATGTGGTAYCAYATGGARAGYACNCARGAR ACNTAYMGNYTNTCNGAYCARYTNATHMGNGCNATHGGNAARGGNAARYTNCAYGAYMGN GARGARGAYATHAAYTCNYTNATHGAYAARGGNGCNGAYGTNAAYMGNMGNCAYGGNACN YTNYTNCCNYTNCARTAYGCNTGYTGYYTNGGNGAYTGGCAYGTNYTNGARYTNYTNATH CARMGNGGNGCNAARGTNAAYGARCCNGAYGGNTAYAAYMGNACNGCNYTNCAYTAYGCN GCNGARCARGAYGARAAYTGYGTNMGNATHYTNYTNGARAAYGGNGCNYTNGCNGAYATH GGNGAYGGNAAYGGNGAYACNGCNYTNCAYTGGGCNGCNTAYAARAAYAAYACNATGTGY GTNCARMGNYTNYTNCARCAYGGNGCNAAYGTNAAYGCNGTNGAYYTNAAYAAYGARACN CCNATHAGYTGGGCNGCNMGNAARGGNAAYYTNGCNGTNATHCARGTNYTNYTNGAYTAY AAYGCNGAYATHGAYATHMGNAAYACNAGYGGNCARACNGCNYTNAARAARTCNGCNGCN GTNCARGCNAGYGGNYTNAAYAAYGARGARGAYGAYGCNTGYYTNGARYTNYTNGTNAAR GCNTCNGGNCARTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARACNGCNTTYGTN ACNGGNGGNGCNAARGGNYTNGGNAARGCNTAYGTNGARAARTTYYTNGARGARGGNGCN AGYGTNTTYTTYGGNGAYGTNGAYGARGARYTNGGNAARACNACNCARCARGARYTNCAR GGNAARCAYGGNAARGAYMGNGTNGTNTTYTCNCCNTTYGAYGTNACNAAYGGNGARCAR TTYAARGARGCNGTNGAYAARGCNGTNTCNCAYTTYGGNAAYATHGAYGTNTTYATHAAY AAYGCNGGNATHYTNAAYGARGGNGTNTGGGARAARATGATHGCNATHAAYTTYACNGCN GTNGTNMGNGGNAGYAAYYTNGCNATGGAYCAYATGMGNAARGAYAARGGNGGNAARGGN GGNMGNYTNATHAAYATHAGYTCNATHATHGGNYTNTCNACNCAYGARTCNATGCCNGTN TAYTGYGGNACNAARCAYGCNGTNMGNTCNTAYACNAARTCNYTNACNACNATHCCNGGN YTNGARTCNGAYATGGGNATGGARATHGCNGTNYTNTGYCCNGAYGCNGCNAAYACNGAY YTNATGACNAARYTNGAYGAYGARAARYTNCAYGGNTAYAAY------------GARYTN AARGARGCNATHGAYGARMGNATHATHTCNGTNTCNACNGTNGTNGAYGGNYTNTTYTCN YTNYTNAARAARGARGAYTCNATHAAYGGNGCNATHYTNYTNGTNACNAARGAYGARAAR AGYTTYCARGARATGGARCCNGTNGAYYTNGGNAGYGARTGGCCNGTNCCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNGAYTAYCAYGARATGGGNTTYGTNTAYAAYMGNGCN ACNGGNACNGAYGTNGAYAARGTNTAYGARTTYGGNTGYTAYYTNATGGCNCCNCARCAY TCNYTNGTNYTNTTYCCNTCNACNGCNCAYTTYYTNGAYYTNGARYTNTCNGTNATGAAY AARGCNGGNYTNACNATHGGNYTNCARGTNTAYYTNCARTAYYTNYTNMGNCCNAAYGAR YTNTCNCARATGTAYMGNAARTAYAAYMGNGAYTAYAARAARATHATHTAYATHATGGCN GARAGYACNGTNAARAAYATGGCNATHGARTTYACNYTNGAYCARTAYMGNYTNAAYMGN TCNATGGTNGARGCNAGYGTNTTYCAYMGNYTNAARMGNGTNYTNTCNGGNGAYTGYTGY AAYACNMGNTAYGARMGNTTYCARACNTCNTCNCARACNACNGCNTGYAAYGCN------ ------AAYGCNGCNACNTGYGAYCCNGGNTTYCAYGTNGAYYTNGCNTTYTTYCARATG GGNAGYATHACNATHCCNAAYGAYGTNATGAAYCAYTAYYTNAARCARATHATHYTNAAR ATGGARACNGARMGNGARGARTAYGTNCARCARNNNACNGTNGARGARAARYTNTCNAGY YTNYTNGTNCARGARATHACNAAYCARGCNAAYGARATHMGNGCNATGGCNAAYGCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GGNAAR GAYTTYGAYACNTTYTGGATGTCNCARAARATHCAYAAYGAYTTYTCNAARYTNYTNATH AAYMGNAAYGTNGAYTCNTCNYTNMGNGCNGARACNGARACNTCNTCNYTNGAY---YTN CARACNATHGCNAARGAYYTNTAYACNACNYTNGARGARTCNGARTCNTAYGCNCARACN GARAAYGAYTTYAAYACNAAYTCNACNTCNGCNATHAAYGTNTCNAAYTCNAARATHGAR GARCAYYTNMGNTCNTGGYTNGTNGGNGTNGCNTCNTGYCCNATHTAYTAYAARTGGGAR GAYTTYGGNGCNTTYTAYTGGCCNMGNTGGGTNAARACNGGNTCNTGY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATHATHGCNTCNTCNGCNGTNGCNYTNTTYGTNTTYYTNATHYTNATHGTNGTNATHGTN TTYGCN------AGYTGYTTYTCNCARAAYTGGATHMGNTCNAGYATGAARMGNGARGGN AARGTNAARATGCCNMGNTCNTAYTTYGAYAARAARMGNGARGCNAARMGNMGNYTNATH GCNGARTCNATHGCNCCNGCNCCNGCNCCNGTNGTNAAYGGNTCNYTNCCNCAYYTNACN ATHCCNACNYTNGAYAAR---------GARACNYTNGTNCARGGNTGGAAYCAR------ ---AAYACNATGAARATHTAYGARGARATGGGNAARACNATGGARYTNGGNGAYGARATH GAYGARGARTTYCAYATHGARACNACNATHGTNGAYAAYGARGTNYTNGAYGTNGGNCCN TAYAARAAYATG---GARTCNACNAARGCNCARCCNGTNGAYGGNAAYGTNTAYGCNAAY CCNTAYYTNTAYAGYAAYAAYGAYMGNGTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------MGNAGYGGNCARGAYMGNGAYMGNAAYMGNMGN--------- ---GARTCNGAYAAR---AARAARCARGGNGARGAYTAYGAYCCNGCNGARCCNACNGAR GAYGAYGAY------GAYGGNAARGAYAARGAR---TCNAGYYTNTAYTGYCAYGTNTGY TCNGTNTCNGTNTAYGAYGAYGARAGYTTYCARMGNCAYYTNAAYGGNYTNAARCAYAAR TCNMGNATGGARGAYATHGCNACNGTNCAYACNGTNMGNTCNTCNCARYTNAAYTTYMGN YTNAARGCNGARGARCAYYTNMGNAAYATHGARMGNMGNGARGGNMGNGAYCCNGAYTAY TTYTGYAARATHTGYAAYAAYGAYYTNGCNATHCCNTGGGARAARCAYMGNTAYTCNAAY ATHCAYAARCARMGNYTNYTNCARGTNMGNAARGGNTGYGGNTGGTGYAARGTNCAYGAY TTYACNAAYTTYACNGARGTNYTNGARCAYMGNGARACNGARGARCAYCARCARAAYGCN GAYMGNTAYGGNAARAARGARGAYGARAARGAYGAYTCNMGNCARMGNATHAARGAY--- ---------------------GGNAARGARMGNAGYAARTCNYTNGARAARAGYAARGAR GAYAARGARGARGTNGARGARGARGARGARGARGAYYTNACNATHCCNGARTAYGAYCCN GARAGYCCNGTNGGNATGAGYTAYGTNATHCCNGTNACNGGNTAYTTYTGYAARYTNTGY CAYAARTTYTAYAAYAARAARTCNGCNMGNGCNACNCAYTGYCARAGYACNATGCAYTAY GARAARTTYAARGTNGCNACNGARGCNAARATHGCNGCNMGNGARAARAARATGGARGAR GARMGNYTNMGNAARGARAARGARGARGARGARGCNATGGARGARGARGGNGAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNGARTTYTGGCAYTAYATHCARCARACNATHGCNTAYGAYCCNGARACNMGNGARYTN AARAARATHTGGACNTGYAARATGCCNGTNCAYGGNGCNYTNYTNGGNTAYMGNGARCAY YTNYTNACNYTNGGNGAYAARATHAAYCARYTNGGNGTNGAYMGNGCNGARACNGCNYTN YTNTGYGCNATHAGYATGACNAGYATHGAYTGYCCNAGYYTNGTNAARCCNGAYACNGTN TCNGARGTNCARAGYGTNYTNATHGARTCNYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARAGYTAYGAY TTYCAYTCNGTNYTNAARTCNAGYATHGAYMGNGGNTTYAAYTGYATHATGGAYGCNYTN GCNGAYCAYTTYAARCARGTNACNGCNGGNGTNCAYGARCAYTCNAGYATHCAYGAYGTN TCNYTNGCNATGGCNAARYTNATHCCNGTNYTNAGYGCNYTNYTNCCNAARATHTGYGGN GAYGCNCCNAAYCCNTTYATGCARGARYTNYTNATGATGGARGARYTNAARCARYTNGCN GCNAAYGTNTAYGARGCNTTY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGGCNGCNGCNTGYATG AGYYTNGAYAAYCCNGCNTTYMGNTCNTTYATHGGNTAYGCNGCNGTNGTNYTNGTNAAR ATGATGYTNATGAGYYTNYTNACNGCNTTYAAYMGNATHACNMGNAARGTNTTYGCNTCN GARGARGAYACNGCNTAYTTY------AARGARACNMGNAARGGNGTNGTNYTN---AAY GAYCCNACNGTNGARMGNGTNMGNMGNGCNCAYCARAAYGAYGTNGARAAYATHYTNGCN TTYGTNYTNYTNGGNGCNATHTAYTGYACNACNGGNCCNGTNYTNTCNACNGCNYTNYTN CAYTTYMGNGTNTTYACNGTNGCNMGNATHYTNCAYTCNATHGTNTAYYTNYTNCARGTN CCNCARCCNGCNMGNGCNACNGCNTTYTTYGTNGGNYTNGGNGTNAAYATGTCNYTNGCN TAYMGNATHATHYTNCARGCNGCNTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATHGAYGARCARAGYMGNAAR MGNATGCARATHGARGTNCARMGNATGGARAARATHTCNYTNCARCAYYTNCARGAYYTN YTNCAYMGNACNGARGARGTNYTNGGNYTNTGGTGYYTNYTNATHGAYCAYCARTTYCAY ATHYTNGCNGCNGCNATGGCNCCNGAYATHCARAAYCARYTNMGNAAYATGACNTTYAAR ACNYTNGTNACNAGYGGNAARGAYGTNTGYAGYACNYTNATHATHTGYYTNGTNAGYMGN TAYYTNAAYGAYAAYGCNACNATHGAYGCNATHAAYGAYMGNYTNMGNGARGTNTGYCCN ACNYTNTAYAGYACNGAYGAYGCNACNTGYTCNAARTCNAAYGARYTNYTNCARGCNGCN AARATGAAYCCNAAYAARYTNGARAARGARCARCARYTNCARGARGCNYTNCARYTNYTN AARGGNGTNTCNCARCCNYTNAAYYTNTCNGTNATHTGYTCNCARYTNGCNGGNGTNCAR TTYTAYYTNGGNATHGTNGARYTNGCNYTNAAYGARGCNGGNAARYTNGAYCCNCARGGN ATGGCNATHCAYTTYTAYAAYAAYGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATHAARGAYTTYAAYGTNCCNTTYACNCAYGCNAARGGNMGNGCNAARGTNMGNGARGAR TTYATGAARAAYAARCAYGTNACNGAYATHMGNGTNATHGAYATGYTNGTNATHAARGGN CARATGGARYTNGTNGARACNGCNAAYATHTGGAARCARMGNCAYCAYATHATGGCNTAY TTYAARGAYACNGTNAAYCCNAARCCNACNGAYTTYYTNAGYAARTTYTAYGARGGNCAR GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYAAYYTNMGNMGNAARATGAAYTCN GGNGAYAAYATHTAYMGNMGNATGTCNGGNCARCCNYTNTAY------AGYCAYGTNGAY CARGARYTNGAYCAYAARGTNAARMGNGTNTCNGAYAARTTYTCNGARACNGTNAAYATG GTNGCNAAYGARCCNTCNYTNGCNTTYTTYMGNATHCARGARCAYGTNMGNAARACNYTN CCNCARYTNGTNGARACNAARCAYGARGTNGARGAYGTNCARTCNAARGTNCARGGNACN TGYTTYGAYGCNGAYTAYGCNGTNAAYGCNGTNAARGCNATGCARAGYAGYGCNATHCAY TTYCARAAYATHCARGAYYTNYTNAARAAYGCNATGTTYATGAARCARCARATHGCNTAY GARGAYAAYAARMGNAARCARGGNMGNAGYAGYCCNATGGCNGGNGARMGNAARTTYCCN YTNCCNCCNTGYMGNATHTGYAGYGCNCCNGGNGCNGGNTTYCAYTAYGGNGTNAAYACN TGYGARGCNTGYAARGGNTTYTTYCAYMGNAGYYTNAAYCAYTGYTCNMGNTAYAARTGY GTNAAYAARMGNAAYTGYACNATHMGNCAYGGNAARGGNAARATGTGYMGNYTNTGYMGN TAYCARAARTGYYTNGAYATGGGNATGTCNAARTCNGCNATHAARACNGGNMGNTAYAAY TAYAARAARAARACNGAYGAYATHYTNGARGTNAAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYGCNTGYYTNAARACN GARGARGARYTNGCNGARGARMGNAARGCNMGNMGNAARYTNGARCARCARAGYCAYGAR AGYTCNTCNAAYAARAARAARAAYAAYAARCCNAARAARACNACNGARAARGARMGNYTN CARCARYTNGCNTTYGGNTTYGCNAARACNGCNGGNAARAARAARTCNGGNAARAAYMGN AAYTCNAAYAAYCARAARAGYCARGARAARGARTGGGARCARTGGAARGARCAYGAYCAR GARGTNGTNGARGAYCARTTYMGNGARGAYYTNGARAARGCNYTNATGGARAGYCARYTN CARYTNGTNAARAARAARACNGARGARAARCARAARAARGARMGNATGAAYTCNGCNACN GARCCNACNATHGARGARGARGARGGNAARAARAARAARAARAARGAYAARACNAARACN ATGTCNYTNGGNGARTTYAAYAAYYTNCARAAYCCNAARCCNCARAARATHTCNGAYGAY TCNCARGAYGARGAR---------CCNTCNMGNCCNCCNATHCAYCAYMGNGTNCCNTCN GCNGAYAARGAYTCNAARTTYTTYAAYAGYGCNCARCAYGARGCNAARCARATHYTNAAR AARGAYAARATGCARGARGARTAYMGNAARACNTGYGCNGCNGAYAAYGCNGTNGTNGCN AARYTNAARTAYGAYATHGARYTNMGNGAYAARACNATHAARGAYYTNAARCARAARATG GARAARAARGARACNGARATGAARCARGTNAARCARMGNAAYAARCARYTNTGYGARATH YTNGCNCARGGNGARATGAARGAYAARGCNCARGTNYTNYTNCARGTNGAYGARYTNAAY AAYGTNAARGAYGARYTNATGGARCARGTNACNTCNYTNACNGCNGARYTNGARAARGAR AARTCNAARAAYMGNTCNYTNAARCCNGARGTNGAYAARGCNAARGGNGGNAARCAYGGN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MGNACNGCNAGY GCNTCNAGYYTNTAYTGGAGYTGYGGNTAYTGYGAYTTYCARAGYAGYAGYCARGCNGAR ATHAARGARCAYTCNAAYMGNACNCAYCCNGGNAARCCNCAYMGNTAYGTNGCNYTNATH AARAAYATGACNCCNGAYTCNATHATHAAYAARAAYGCNAAYAARTAYAAYACNAAYGCN TCNCCNTCNYTNTCNGCNGTNAARAAYACNCCNTCNTTYTCNTCNGTNAARYTNGAYAAY GTNGCNAAYAARTTYGAYMGNGARGGNGCNGGNGCNGGNGAYGAYATHGTNAAYYTNTCN AAYAAYGCNGAYGARAGYACNYTNAARGTNAARATHGGNACNCCNMGNGGNCCNAARAAR GAYAAYGCNACNTAYAARTGYTAYCAYTGYACNTAYACNGCNAARMGNCAYTCNTCNATG AARTCNCAYATHTAYTAYAARCAYMGNGGNAARGGNYTNYTNGCNGTNGAYGARGAYACN AGYACNGGNGGNCARGTNTTYTTYTGYGCNMGNGAYGAYTGYACNTTYAARTCNACNAGY CCNACNTCNTAYYTNAGYCAYGTNGARCARTGYACNCCNTGGCAYAARCCNGARYTNGCN GAYGTNGARGTNGARCCNCAYATHMGNGARTGYYTNCARCARACNGTNACNTTYGCNGAR ATGGCNYTNGAYAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AGYGAYGGNAAY AAYTTYCARGTNGCNGGNATHMGNGCNGTNTCNCAYTCNACNTCNGAYGTNGCNCARGCN GCNACNYTNGCNATGGAYTCNYTNAARGAYTGYATHGARAARYTNGGNCAYCARACNTCN GAYGTNACNTCNYTNTCNYTNTAYGTNGGNAAYATGTCNAAYTAYGCNGCNATHAAYACN GTNTAYAARAAYTAYTTYGARGTNAAYCCNCCNACNMGNATHTGYATHCARGTNTGYYTN CCNCCNACNGTNTTYTTYCARYTNGAYTGYGARGGNGGNACNGCNGARAARGARGAYMGN MGNACNATGTAYGTNCARAGYYTNTCNYTNTGGGCNCCNGCNAAYYTNGGNCCNTTYAGY CARTCNATHTCNYTNAAYGARAARATHTTYGCNTCNGGNACNACNGCNYTNGTNCCNTCN ACNYTNAARYTNATHGAYGGNGGNGTNGGNGTNCARAGYMGNGTNGCNYTNACNCAYYTN ATGGARAARTTYTAYGGNYTNTGGCCNCAYTGYGTNGTNGGNAAYTCNCCNGCNATGTTY TGYTAYGTNACNMGNMGNGARCAYATHCCNCCNGCNMGNMGNGARTTYGAYTCNATHYTN AAYGARAGYMGN------CCNGGNGCNYTNAGYYTNACNCCNATHGTNCARTAYTGYATH GTNCCNMGNYTNCCNCARGGNGCNYTNGTNGARTGGCARGCNTAYTCNTGGATGTTYAAR GARGARGARGARGAYGGNMGNATHGGNGTNGCNCARTCNGCNAARGARTTYTCNCAYTGG TCNTAYGAYYTNGAYTGYGTNTGYTCNAAYGAY------------------GTNGCNTGY GTN------------------------------------------YTNYTNCARGARTAY AGYAARGCNATGGARAARMGNAAYMGNAAYMGNACNGGNGGNYTNGCNAARATHTTYTAY YTNGCNGAYMGNATHTCNTAYAARGAYATHGTNGARAAYTTYTCNCARGARYTNCCNGAY YTN---GAYMGNGAYAARATHCCNATGYTNTCNTTYGTNCCNGTNYTNGGNYTNGAYACN GARAARCAYYTNYTNTCNTGGTGYCAR--------------------------------- ------------------------------------------------------------ ------------ACNAGYGCNGCNCAYYTNATGYTNAAYGTNGARCARACNAARGARAAY CARCARMGNAARGCNGARMGNCCNYTNGCNTGGATHGCNCAYGAYCCNAARAARMGNTCN TTYGTNMGNAAYGAYYTNACNTAYACNAARGGNMGNATHGTNGTNCARTCNAARGGNYTN TAYCAYYTNTAYAGYCAYATGACNYTNAGYTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARGTNAARGARMGNMGNMGNAARMGNACNGCNGAR GAYGARMGNAGYMGNGCNYTNGARAAYGAYYTNYTNGARATGAARTCNCAYYTNGTNMGN TCNGTNGGNGCNATGTCNGARATGGARGARATHAARMGNMGNYTNGARAARAGYGARMGN CARMGNACNCARYTNTCNGAYCAYATHGARACNYTNGTNAARGAYYTNGARAAYMGNGAR MGNCARAGYGCNAARGTNATHAAYCARYTNAARGARACNTCNGAYAARTAYGAYGARTCN GAYMGNCARMGNTCNYTNATGTCNACNCARYTNGARGAYATHCAYCARAARYTNAARGAY GTNTCNMGNGAYYTNGARAARACNACNCAYGARYTNMGNAAYACNCARYTNYTNYTNGCN GARACNGARAARAARAARGAYGARTTYAARGGNMGNGCNCARGARACNGTNMGNCARTGG AARGCNAARGTNAARCARYTNGARMGNGAYYTNGAYMGNCARAARCAYGGNAAYGGNCAR ATGATGGCNMGNCAYGARCARYTNGTNAARGARATGGARGGNCARAARCARCAYGGNACN TAYAGYCARYTNCARYTNGARAGYYTNAARMGNGARYTNGCNGAYGCNYTNGCNGTNMGN GCNGCNCARGAYGARCARYTNMGNYTNAARGAYATHGARGTNAAYGARYTNAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYGAYGARGAYGGNYTNAGY GCNTTYAGYTCNGTNGAYGAYAARMGNGCNCAYCAYAAYGCNYTNGARMGNAARMGNMGN GAYCAYATHAARGAYAGYTTYCAYAGYYTNMGNGAYTGYGTNCCNCARGAYGAYAAYAAR ------ACNAAYTCNTCNAGYAARACNTCNMGNGCNCARATHYTNMGNCARGCNTCNGAY TAYATHATHMGNATGMGNGAYAARACNTCNCARAAYGAYMGNCAYATHCARATHYTNAAR CARCARAAYGAYGARYTNCARGCNCAR--------------------------------- ------------------------------------------------ATHAARGCNYTN CARAARTCNCARGCNGGNGGNAARGCNYTNATHAAYTCNAGYTTYYTNGARGAYMGNGGN GAYGAYGAYTAYAARAGYTAYGARGAYGARCCNGTNGTNGCNTCNCCNCCNAARMGNAAR AARGTNAARACNAGYCAYAGYATHAARTCNCCNTCNTCNGGNYTNMGNYTNGGNYTNTCN MGNAAYCARMGNGTNAARCCNYTNCAYGGNTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNCAYMGNGGNGTNYTNTCNTGYATHTCNGAYYTNAARTCN------ ---------------TAYGGNYTNTGGCCNAARGARTCNATHGAYGGNATHATHYTNCCN MGNYTNMGNATHGGNATHGGNMGNCCNTCNTCNAARTCNGARGTNATHCCNTAYGTNYTN GGNCCNATHCCNAAYTAYGARGTNAARGTNATHGARGCNGCNATHGAYMGNGGNATG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARAARAARGCNATH GTNAARMGNAGYAARAGYGCNGCNGCNGAYYTNMGNAARCCNAARGTNGAYGARTCNACN GAYAARGARGAYGTNTCNGCNGAR------YTNAARGARAARYTNAARAARACNCAYGGN AARATGMGNMGNACNGGNTCNGARTAYCARTCNAAYTTYAARGCNCCNTCNGCNTAYTAY AGYAGYMGNGGNGTNTGGAARGGNGCNGAYCCNCCNCARYTNATGCCNGTNGCNAARGAR GTNGAYGCN---------------AAYGTNAAYAAYAAYGCNGAYGCNGAYGCNGCNCCN YTNTCNAAYTGGTTYGCNGARGTNGTNGARYTNMGNMGNMGNGCNGAYGARTAYMGNAAR MGNGCNCARGGNACNCAYTTYTCNMGNGARCAYYTNGTNCARYTNATGGCNCARCARAAY GARTGYTGGGAYGTNGARTCNCARGCNTCNTCNACNGTNAARGCNYTNAAYYTNGARGCN CCNAARATHAAYAARAARTTYCARMGNGAR------------------------------ ---------------------------GAYMGNGAYTCNCCNGTNYTNTCNGAYATHGAR ATGGARGARGARCARGTNGARCCNACNGTNGTNAARAARAGYTAYAARTCNGCNTCNCCN GAYGGNCARMGNATHGCNMGN------------ATGAARMGNGAYAARGARGCNYTNTCN CARCARCARAGYAARATGAARGARAARGCNCARAARGARMGNGAYATHGARYTNGGNGAR AAYGGNGAYGARGAYGTNGTNGAYGARGARGGNMGNCARCCNACNCCNAARYTNAARCAR ACNMGNACNTCNGCNAAYMGNCAYCAYYTNGAYYTNACNACNCCNGCNGTNGGNGGNGCN YTNYTNACNTGYCCNCCNTCNAARAGYAGYAARATGATHGTNACNTCNMGNTCNGGNGAY AGYTAYGTNACNGCNTCNGAYAAYATGGARGTN------GARCARAARAARTTYGAYATG GAYAAYYTNAARACNMGNCCNATHYTNGGNCARCCNTCNGGNGAYACNCAYGCNYTNMGN GAYGAYGAYGCNTCNTCNGAYMGNCCNYTNAAYACNMGNTAYGTNCCNTCNCCNGCNYTN ATHACNAGYGAYGARGAYAARGARAAY---ACNCCNTCNAARAAYYTNTCNAARACNACN AARCCNAGYAGYYTNACNCCNGTNCARGARGGNGCNGGNAARACNTAYATHAARTCNAAR CCNTTYATHACNYTNGAYGAYGTNMGNTCNAAYGARATGGCNGCNATHGAYGAYGAYGTN ATGTCNGTNTCNATGATGTCNGTNGCNTCNAGYGCNTCNYTNGCNTCNGARGTNYTNGAR MGNGCNMGNAARMGNCARAARGARTTYTGGGGNAAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GGNGCNATHGCNACNATHMGNCCNAGYACNGAYAAYCAYGTNAARGGNTGYGTN TGGGARATHGAYGCNGAYCARGTNGARAAYYTNGAYMGNCARGARTGYAAYTAYAARGCN GTNGARGTNGAYGTNYTNYTNGAYATHGGNGCNACNGTNTCNTGYMGNACNTAYGARATH AAYMGNGARGTNYTNCCNAAYGAYACNAARCCNCAYCCNTTYTAYAARMGNATHTGYATH GARGGNGCNAARCARCAYGGNYTNCCNGARGAYTAYATHMGNTTYYTNGARAGYTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GAYGCNTTYGGNATGCARGCNTTYAAYCCNGCN---CCNCARTCNGARCAR GARYTNATGGAYATHMGNGAYGGNTTYAGYMGNGGNYTNTCNTTYGGNACNGAYGAYTTY AAYYTNGAYGAYYTNGAYCCNYTNAAYCARMGNATG------------------------ ------------------------------------------------------------ ---------ACNAARCCNYTNGAYAARGCNGTNTCNACNTCNMGNAAYAAYYTNAARAAR CARAARCCNTCNMGNGGNGGNAARATGGAYTCNAARCAYTTYTCNTCNMGNTCNACNACN GAYAAYYTNCCNAGYTCNYTNAGYACNCCNGGNGARMGNGCNGGNYTNAGYTCNACNTCN CCNGCNGCNGTNGAYTCNTCNGTNCCNACNTCNTCN------ACNCCNAAYACNATGTCN CCNCAYYTNTCNACNCCNGCNGAYATHACNTCNCAYTCNACNAAYCCN---GCNATGGCN ACNGARGCNGARGTNGAYACNACNACNMGNYTNCCNCCNGAYGCNAAYGAYTCNGARTCN TCNCAYTCNTCNACNAGYGAYAARTCNTAYGAYCCNAARAAYGAYTCNTCNAAYTCNTGY TCNAGYYTNGGNAGYTCNYTNTCNGCNGTNATHTCNTCN------------TCNTCNAAR GGNCAYAAYAAYGAYGAYTTYYTNAAYTCNGAYTTYCARGGNAAYAGYYTNTCNAGYACN ACNGAYGGNCCNAGYYTNTCNCCNCCNGCNAARAAYTCNATHACNTCNTCNAAYACNATH AGYAAYGGNCARAAYATHACNTCNACNGTNGGNAAYACNATHACNTCNTCNAAYTCNAAY AARGAYAGYGTNTCNGCNAARGARMGNAGYAGYGARGAYCARAAYAARGAYGGNYTNTCN TCNACNCARAAYACNAARTCNGTNACNGGNYTNCCNTCNGGNTCNAGYYTNYTNAARGAY TCNAARCCNTCNATHGARGAYTCNTCNCARCCNTCNCCNTCNGCNMGNGGNGTNAARMGN CCNCAYGAYGARATHGARGAYACNTGYGTNAGYTCNAAYTCNCCNAARCCNTCNCCNCAR AARAAYAARAARMGNTGYTTYACNTGYAGYTGYMGNYTNGARYTNGCNCARMGNACNATH GGNAARTGYMGNTGYGAYCAYGTNTTYTGYCCNATGCAYMGNYTNCCNGARYTNCAYGAY TGYGARTTYAAYCAYAARGARGAYGGNMGNMGNGARGCNMGNGARAARATGGTNAARCCN ACNMGNCAYATGGGNACNTCNTTYMGNMGNGAY--------------------------- ------------------------------------------------------------ ------------------------GGNTGYTGYAAYAARGARCCNTGYTTYTGYMGNTCN GAYGTNATHTTYTAYGAYGGNGTNGCNTAYGAYCARAARCCNTTYATHCARGGNAAYYTN MGNACNMGNCCNGGNAAYACNATGTAYTTYGARGGNAARATGGTNGGNCCNTTYAAYCCN GGNAARTCNCCNYTNMGNTTYGGNCCNAAYAARACNMGNGARACNCAYCCNAARGARAAY TGYTAYAAYTAYAGYATHAAYTCNTAYTCNMGNCAYCCNTGYTGYMGNACNTCNATHTAY GGNGAYACNYTNCAYCCNTTYCAYAAYACNCARAARYTNGCNTAYAGYMGNATGGGNYTN CCNCAYGGNAARACNATHGGNTAYTTYMGNTTYMGNCCNGARMGNATHTGYTAYGAYMGN GAYCCNCCNGTNGCNMGNATHCARGAYTGYTGYGAYTGYCARCARTTYGARTAYGAYGCN AGYCARTAYGCNCARGAYGARTGYCCNGGNAAR--------------------------- ------------------------------------------------------------ ---YTNCAYACNCAYCCNGTNCAYMGNATHTCNTTYATHTCNMGNGAYACNACNGAYAAY MGNGCNTTYGGNTAYATHGTNGGNTCNGGNGAYGGNAAYCAYACNTTYTTYGCNATHAAR ACNGCNGCNGCNGCNGARCARYTNGTNYTNACNYTNMGNGAYYTNTTYCARGTNGTNTAY GARATGAARAARAARGARGTNGAYGAYGCNAARGARAARYTNGARAGYGARACNGCNAAR GARGAYAAYATGGCNGARAAYGGNAARCCNTCNGGNGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNMGNGARATHGTNATGTCNGGNATHACNTGYYTNACNTGYAAYGTNGGNTTYGARGAY GTNGARYTNGGNMGNATHCAYTAYAARACNGAYTGGCAYMGNTAYAAYYTNAARMGNAAR GTNGCNAGYYTNCCNCCNATHACNTTYGARAARTTYGARGARMGN---------CARMGN GCNCARGARCARYTNGAYTCNACNACNGARAAYGARMGNTGYACNTGYAARCCNTGYAAY AARTGGTTYAAYACNAARAAYGCNTAYGAYAAYCAYYTNCARTCNAARAARCAYMGNGAY GTNATHTCNGGNGCNGCNCARATHAARAARGAYAARAARAARAARGCNGTNCCNAARCCN AAR---------------------------GARATHAAYGTNGARGARAAYATHTCNGAR GAYGARGAYGAYACNGAYGCNGARTCNTGGGAYAGYTAYGAYGCNAGYATHATHGCNYTN GARGARTGYYTNTTYTGYTCNYTNGTNAGYCCNTCNATGGARGARAAYYTNACNCAYATG ACNTCNTGYCAYGGNTTYTTYYTNCCNGAYGCNGARTTYATHTGYGAYYTNGARGGNYTN ATGTCNTAYYTNGGNGARAARGTNGGNGCNGGNTGYGTNTGYYTNTGGTGYAAYGARAAR GGNMGNMGNTTYAAYAAYTCNAARGAYGTNCARAARCAYATGATHGAYAARGGNCAYTGY AARATHTTYCAYGARCARGARACNYTNTAYGARTTYACNGAYTTYTAYGAYTAYTCNAAR AGYTAYCCNACNGGNGARGGNGARGAYTCNGARACNGCNGTNATG---GARAAYGTNGAY ATHATGGARYTNGAYGGNAAYGGNTAYTCNYTNACNYTNCCNTCNGGNACNGTNATHGGN CAYMGNTCNYTNATGMGNTAYTAYMGNCARAAYYTNGCNCCNTAYMGNCAYGARAARACN AARAGYGTNYTNCCNAARATGYTNGCNCAYTAYAARGCNYTNGGNTGGACNGGNGCNACN GGNCCNYTNGTNGARMGNMGNGCNAARGAYYTNCARTAYATGCARMGNATHMGNAARMGN CAYTTYATGAARYTNGGNATHCARGGNAAYAAYYTNMGNCAYMGNYTNMGNCAYCARAAY TCNTCNYTNACNTCNGCNYTNACNATGGCNGTNCCNAAYACNGAYAARGCNACNATGTCN GTNGCNACNCAYAAYAARGARATHYTNYTNAGYTGYYTNTTYATGGARGGNGTNGGNAAR TTYGCNTCNGTNTTYGGNCARGARTTYGGNGTNTAYYTNATHCAYGCNYTNTAYCCNYTN GTNGARAAYYTNGGNCAYGARAAYATHCAYATHAGYAGYACNGCNTTYGAYACNYTNACN CARATHTGYTCNGCNTGYCARTAYMGNTCNYTNGAYCAYYTNATHCARAAYAAYGCNGAY TAYYTNGTNAGYAGYYTNTCNYTNMGNYTNMGNCAYTTYAAYCARAAYCARMGNACNACN MGNYTNYTNTGYGTNATGYTNMGNTAYTGYTCNGARGAYYTNYTNCCNYTNGTNGARCAY AGYATHGGNGARATHYTNGAYACNYTNGAYGAYCAYTAYACNGARGAYYTNGTNYTNTTY ATGCCNGTNYTNYTNGARYTNACNTCNGCNATHGGNMGNTGGTTYCCNCCNATHGTNGAR AARTCNGGNGGNGAYACNGTNGAYCAYGARAARTCNACNCCN---------------GTN TCNTCNYTNGARGARTAYGTNMGNYTNAARMGNACNGCNGAYYTNGARGAYCARCARAAY GAYGTN------------------------GARMGNTCNYTNGARGAYATHGARAARGAR YTNAAYGGNYTNMGNGARGCNAARGARAARGCNAARGAYACNGARGARYTNATG------ ---------GARAARGARYTNGARGARGARAARCARAARGAYTGYCCNAARCAYATHCAR ATHGTNAARGARGTNYTNTAYMGNGTNAARAAYYTNYTNTCNTCNCAYGAYGCNMGNGTN MGNGTNCARTCNYTNGARGTNGTNACNCARAGYTGYAARGAYYTNGCNTGYCAYGARMGN GARYTNYTNCCNCARATHCAYCARATHTGGCCNGGNTTYTAYCCNMGNTTYCAYAGYGAR GARAARTTYGTNGTNATHAARGCNYTNCARACNYTNAARGTNATGGCNGAYGTNAGYGGN AGYTTYATHYTNCARMGNGTNATGAARGAYGTNATHCCNGGNYTNTCNCARTTYATGGAR AARCARGGNAGYATHAGYTGYGAYAGYMGNTCNACNTAYGGNAAYACNGCNAGYTTYAAR YTNCARATHGCNATHYTNGAYACNYTNGGNCCNYTNGCNGARAARYTNGARYTNAAYGGN MGNAAYYTNGAYGTNGTNGTNAARATHTGYYTNCCNTAYYTNAGYTGYYTNCARCCNGAY AARYTNCARAARGCNAGYATGACNTCNTTYAARTCNTTYATHTCNYTNGAYTCNGAYGCN GTNTGGYTNYTNYTNTGYCARGCNTAYTGYCCNTGGCAYTAYCARGTNCCNGGNGTNGAR TTY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNMGNTCNGGNMGNGTNMGNAARAARTCNGCNAARGTN YTNGARATGGARGARTTYGARCARGCNGARAARAGYACNACNACNAARAARCCNAARACN CCNAARGTNGGNTCNGAYGGNGAYYTNAGYAARAARTCNAARGTNGCNYTNGARGCNACN CCNACNTCNMGNAARAGYAARAARCCNGCNTCNTCNAAYGGNMGNCCNGTNCCNGCNGAR YTNYTNATHTCNCCNGTNYTNCARGAYGTNAARCARGARGTNCARCCNGCNCARGAYGAY CCNAARAGYGTNATHAARTAYYTNYTNACNTCNCCNGTNGCNGGNATGCCNCARCCNATG ACNACNACNGAYATHCCNCARYTNACNCCNGCNCCNGCNGTNTCNGTN------------ ---------AARAARTCNAGYAARAAR------------ATHAARTTYGARGAYGGNACN ACNGCNCCNAARAARAARGARAARAARATGAARATHGARATHATGTCNCCNTCNGARATH GGNCCNCCNGTNTCNTCNGCNCCNCCNCCNAARTCNAARGCNCCNAGYYTNAARATGAAR ATHATGTCNGGNTCNAAYCCNATGACNGCNCARGTNGCNATGGARTCNCARGAYAGYGGN ACN------GGNCCNACNCCNAARGTNAARAARTCN------------------ACNAAR AARATHAARGCNGARGTNAAYGAYGAYGTNCARGARYTNACNAGYCCNGGN---GAYGAR GAYAARGCNYTNAARAAR------------AARAARGTNTCNAARAARAARGARAARYTN ATHCARAAYGCNATHAGYGCNGCNAARCARATGCCNAAYYTNNNNGCNYTNGTNTCNACN ---CCN---------CARACNCAYATHYTNGAYYTNGGNGAYTCNCCNTCNCCNACNACN GTNAARCCNAGYAARAARAARGCNAARAGYTCNCCNTCNGTNAARACNGARYTNAAYACN AGYAGYTCNYTN------GTNATGGAYTTYGAYGARACNGGNGARGGNGAYGARTCNACN YTNGTNATHGCNGARACNGARAARAARAARAARAARGTNTCNGCNAARAARAARAGYCCN AARGARAARGARGCNTCNAGYCCN---AARGCNGARAAR---GCNAARAARATHCCNAAR MGNGCNCCNACNGCNTAYATGYTNTTYTGYAAYGCNCAYMGNCCNGCNATHGTNGCNGAR AAYCCNGGNATHGARTTYGCNGGNATHAGYMGNAARYTNGGNGARYTNTGGCARACNCAR TCNAAYAARCARAARYTNCARTGGMGNMGNAARGCNCARMGNMGNATGAARAARTCNAAY YTNATHTCNACNGGNAARGCN---GGNGGNAARGARTCNYTNACNTCNGCNGCNTCNCAR GGNGTNGGNCCNYTNAAYTCNACNAAYAAR------AARYTNGCNYTNATGYTNCARAAR AGYAARCCNGTNGTNGTNGARGARGGNCCNYTNAGYCCNACNAARAAYTTYAGYATHGAR CCNYTNGAYGTNGCNGCNCAYYTNAARYTNYTNGGNGARTCNYTNAGYATHATHGGNATG MGNYTNCARGARCAYAARGGNATGATHGCNGTNCARGGNAGYYTNTCNGTNYTNYTNGAY TCNYTNYTNTGYGCNTGYGGNCCNYTNYTNTGYYTNACNCARCARGTNCCNGGNATGGAY GGNTGYTCNCCNYTNGTNCAYGCNCARACNYTNGAYAGYGTNGCNTAYGTNATGCCNGGN YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYAARATGAGYAGYGTNCAYCCNAAYGCNCCNCCNCCNCCNTAY--- TCNACNGAYCCNGTNTAYCCNCCN---CCNCCNGCNGGNTAYTAYGGNGCNCCNCCNCCN CARGCNTAYGGNGCN------------------GCNCCNGCNGGNTAYGGNCCNCCNCCN CCN---GGNTAYGGNGCNCCNCCNCCNCARGGNTAYGGNGGNCCNGGNCARCCNGGNTAY GGNCCNGGN---------------------CCNTAYCCNCARCARCARTAYCAYCCNCAR ------------GGNCAYTAYCARCARCARCCN---CARCARGTNGTNTAYATHMGNGAR GARMGNAAR------GARAARGAYAAYTCNGCNGARACNTGYTGYATHATHGGNYTNTGY AGYGCNYTNYTNTGYTGYTGYYTNATG--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARAGYGAYTTYYTNMGNGCNATHMGNAAYGAR AGYTCNATHMGNAAYGGNGARGTNTGYCARAAYCARAAYCARAARAAYGGNNNNAARCAR GARTCNAARCARGAYATGAAYGARAAR---------GAYGARAGYGCNGGNTAYAAYCAY ATGAAYGGNGAYMGNCARGTNGAYACNAAYGARAAYYTNGTNAGYACNAARAARGGNGGN YTNAAYGGNGARATGAARGAYGARTGYGTNAAYGGNGAY---------GCNYTNATHAAY CAYGTNGAYCAYATHACNYTNTCNGGNGARGARGARGARMGNMGNYTNYTNYTNTCNATG GGNTGGGTNGARGARGAYAAYACNGARTAYGARATHACNGARGAYGARATHMGNGARTTY CARAAYYTNYTNGARAAYCAYTGYCAYGGNCARMGNAAYGGNYTNMGNTCNACNYTNMGN AGYGCNYTNAAYMGNAARYTNGGN------ACNGAYGGNATGYTNAAYGGNATHTCNACN GARGAYGARAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYGGNMGNTAYCCNMGNGARTAYAAYCCNAARGTNCAYGGN CCNTAYATGCCNGGNMGNTTYTAYGGNAARCCNGAYACNCCNTTYGGNCARGTNAARYTN GGNGARATGGGNTCNTGGYTNGCNMGNMGNAAYAARAGYCCNCARGGNATHTGGGCNGCN ATHCAYMGNTCNTAYTGGMGNTGGGCNCARGCNAAYYTNCAYGTNMGNCARAGYGGNTTY GTNCCNYTNGGNCARGCNGCNATGGTNYTNTCNATHACNTTYTTYGCNYTNYTNTAYAAR GARMGNAGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARYTNAGYGGNAGYMGNGARCARGARAARATGYTN TCNGAYCARGTNGARCARCARGARCARATHYTNAAYCARYTNCARACNGARYTNMGNGCN GARMGNGARMGNCAYGGNGAYACNGTNCARCARYTNAGYGCNAGYAARAARAAYGGNYTN GAYYTNCARGCNGAYGTNGARGCNATGCARAARCARGTNMGNGARYTNCARGAYMGNGTN AARGCNMGNGARGAYCARATGGTNMGNYTNMGNCAYGARATHGAYAAYYTNCAYCARAAR AGYMGNGARAGYAAYGARATGATGGCNGARAARGAYGGNCARYTNMGNYTNGCNGARATG AAYYTNCARACNGCNCARAARCARGCNAARCAYCAYGCNCARGARATHGCNMGNTAYGAR GAYACNYTNGCNCARYTNCARACNGAYYTNGARAARATHCARGARCARTAYMGNCAYTCN TCNTCNAAYYTNATGGARGCNGAYAGYAARGTNCAYGARYTNAARGTNCARYTNACNACN YTNCARGGNCAYCAYAARGARGCNATGGAYCARYTNACNGAYAARGCNMGNCARYTNGCN GGNATHAARACNGARGCNGCNAARATGGCNCARCARAAYAAYTCNATGAARGAYGARATH ATGATHTAYGAYGAYAARGTNMGNAARYTNCARCARGARYTNMGNAARTCNCARGARATH AAYAARGCNACNGARGARGARYTNCARCAYTTYGAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNYTNGGNCAYATGTCNYTNACNTCNYTNGTN AARAGYATHCCNAARATGGCNGARYTNGGNYTNYTNGAYCAYAGYTCNTCNGARGCNGAR ACNGTNATHAGYMGNYTNAARGAYTCNAARGCNTTYGCNGARGARMGNGTNTCNCCNGTN ACNGTNTTYGTNGCNCARMGNAARTAY--------------------------------- ------------------------------------------------------------ ------MGNMGNGTNACNGTNCARGGNYTNTCNAAYCAYCAYCARGCN------TCNTCN GGNYTNTAYGAYGAYAGYYTNTCNGARTTYAGYGAYAGYGARMGNAAYGARGTNTCNGAR AAYYTNGTNTCNGCNTAYAARAAYATGACNAARGARGARYTNYTNMGNGTNGCNATHCAR GCNAARGCNCARATGATHMGNAARGARAARTAYATHAARGAYYTNGARAAYTAYATHGAY GAYYTNYTNGTNMGNGTNATGGARACNACNCCNMGNYTNYTNACNMGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYMGNTCNACNMGNAAYYTNGCNGARMGNGTNGCNGTNYTN MGNMGNGARAARGARATHATHTAYMGNAARATHCARGARGTNCARCARCARCARGARYTN GAYMGNCARMGNGARCARTTYCARCARCAYMGNAAYYTNCAYAGYCARMGNAARGAYGAR YTNYTNGARACNYTNMGNATHYTNAARGARAARYTNGARGARCARAGYAARACNYTNCAY ---------------------------------------------TCNAAYAGYATHGAY CAYAGYAARAARGARYTNGARTGGGAYGARATGAAYATHYTNGCNACNCAYCAYCCNCCN GAYAARGAYTAYGGNTTYATGAARGTNGAYGARCCNCCNACNCCNTAYAGYAARGTNGCN YTNTCNGAYAAYGARGARGARGARTCNAGYAARGARMGNAARGGNAGYYTNGAYGGNGCN GCNGGNYTNGAYCCNGGNGAYYTNGCNTCNMGNYTNGCNTCNGAYGGNCAYGAYGARAGY MGNAARMGNTTYGCNGAYGAYGAYGARGAYGAYGAYGARTCNGARGAYGAYTCNACNGAR GARGARMGNGCNMGNNNNAARGCNTTYATGATGAARMGNAARATGCAYTAYAAYGARTTY CARGCNGTNCARYTNGCNAARAARYTNATGGCNGARGAYAARGAYGAYGAYGAYGAYGAY GAY------------------------GAYYTNMGNATHAAYCAYTTYGAYATHGGNGAY ACNATHGCNCARMGNMGNMGNMGNGCNGGNGTNTTYAARAAYCARTCNGGNCCNCCNCCN GARMGNMGNAGYACNATHAGYAGY---ATG---ACNAGYAGYTAYCARGTNACNMGNATG MGNAAYYTNTCNGGNGGNAGYAGYGGNAGYACNGCNAGYGGNAGYAGYAGYGGNAGYTCN GTNCARYTNGAYAAYCARTAYTCNTCNACNGARAAYAAYCAYGTNTAYTTYTCNTGYTAY ATHCCNCCNTTYGCNAAYTCNTCNTCNGCNGTNCCNAARCAYAAYGARGAYTCNGCNTCN ACNTCNCAYMGNAARYTNGAYMGNAGYYTNAGYGAYAGYGAYAGYGAYMGN--------- ---------------------------TCNGGNAGYMGNTAYAARACNGARYTNTGYMGN CCNTTYGARGARAGYGGNTCNTGYAARTAYGGNGAYAARTGYCARTTYGCNCAYGGNTCN CAYGARYTNMGNAAYYTNGCNMGNCAYCCNAARTAYAARACNGARYTNTGYMGNACNTTY CAYACNATHGGNTTYTGYCCNTAYGGNCCNMGNTGYCAYTTYATHCAYGARGAYGAYAAR GGNGARTGYCARCARCCNAAR------------------------------------YTN AGYAGYAGYGGNAGYGGNAGYAGYAGYCCNTCNYTNAGYCCNATHYTNCAYGAYCARAAY ------AAYTTYTCNTAYTCNTCNGARTCNTCN---CARYTNAAYATHGAYAAYGCNMGN GTNAAY------AGYTCNYTNACNGTNAAYATHAAY---TAYGGN---------AAYGCN GAYYTNCARTCNYTNGARCAYCAR---TTYAGYTCNGCNYTNAAYYTNAAYMGNAAYTGY ------AAYGARTCNTCNMGNAAYGTNTAYAAY--------------------------- ---------AARTCNGAYGARTAYGAYATHTTYAGYTCNATHTCNGTNTTYAAYGCNGAY GARGTN---GTNGAYAAYGCNCCNYTNAARCCNTCNAAYTCNTAYTCNTCN---TCNCAY TGYAAYCARAAYYTNGAYAAYTAYCCNGGNTGYGTNAAYACNTCNTGYTAYTGGCCNTCN ------AAYATGTCNTCNCARAGYATGGCNCCNGTNGAYCCNTTYAAYTAYTCNCCNACN GGNTCNACNGGNTCNACNAGYTCNTCNGGNTCNTCNGAYTCNAGYAGYGGNAGYGAYTGY AGYGGNAGYACNGARAGYYTNGTNAGYTCNGGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHAARAGYAARACNGGNGAYGTNATGTTYGARAAYGARAARATHATH GARMGNTGGAARGARTAYGTNGARGAYYTNTTYAARGAYAAYMGNCCNAAYAAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CCNAAR TTYACNCCNGAYTGYMGNATHCAYGGNTAYCAYMGNGCNGAYGCNAARGAYTAYTGYGAY ACNGARTAYGARATGGGNYTNYTNGCNAAYCCNGARAAYTAYCCNTTYTGYAARGARTCN TAYTGYGARACNTTYACNATGACNAAYGTNGTNCCNCARGTNCCNGGNTTYAGYTGYGGN CCNTGGTAYGAYYTNGARYTNTAYATHMGNGARAARYTNGTNYTNAAYAAYAARAGYGTN TAYGTNTGYTCNGGNCCNYTNTTYYTNCCNGTNGAYGARGGNGARAARATGGTNAARTCN TTYGAYGTNYTNGGNGAYGGNGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARCAYMGNYTNGCNCARGAYGGNATHAAYGARGTNAARYTNCCNCAY ATHTTYGCNGAYGGNATHMGNATHGGNGGNGCNGGNGARYTNGARMGNYTNAAYGARGCN GGNGARYTNMGNGCNYTNYTNGARGGNTAYCARAARGTNAAYGTNMGNTTYGCNTGYGAR MGNTGYGGNGGNTAYMGNTTYGTNCCNTGYGARTTYTGYCAYGGNAGYAARMGNTCNYTN ATHMGNAAYCAYTTYACNGARGAYTTYTTYGCNYTNMGNTGYATGCAYTGYGAYGAYAAY GGNYTNMGNMGNTGYGARYTNTGYAARGARCARCARGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYGAYCARGARATHYTNATHAAYGTNCCN TCNGARYTNCARMGNYTNTCNATHYTNCARGTNYTNACNMGNGAYYTNATHYTNGCNTCN GAYGARTCNTGYAARGCNGTNGCNCARATGACNCCNGGNTTYGTNGGNGCNGAYYTNMGN GGNYTNTGYGARGARGCNGTNGAYTAYGCNCARAAYMGNTCNTCNGARGARGARTCNACN YTNACN------ATGGARGAYTTYTAYCAYGCNYTNCAYAARACNATHCCNTCNYTNAAR AARGGNAGYGARTGYGTNGTNGAYYTNACNCCNGTNMGNTGGGAYGAYATHGGNAGYYTN GAYCARATHAARGCNGARATHMGNCARTCNATHGARTGGCCNYTNATHTAYCCNGARGTN YTNMGNMGNATGGAYYTNCCNCCNGCNAARGGNATHYTNYTNNNNGGNCCNCCNGGNNNN TGYAARACNACNYTNGTNMGNGCNGCNGCNACNTCNTGYAAYGTNTCNTTYYTNTCNYTN AGYGGNGCNCARGTNTAYTCNGCNTAYGTNGGNGARTCNGARMGNYTNATHTCNCARGCN TTYCARAARGCNMGNGCNYTNGCNCCNTCNATHYTNTTYTTYGAYGARATGGARACNYTN GTNGGNAARMGNGTNGCNAAYGTNGGNCAYAAYMGNGTNCARGARMGNATHYTNTCNACN ATHYTNAAYGARATGGAYGGNGTNGGNAAYMGNYTNGAYTCNAARATG---GCNGCNGTN AAYCAYGARGCNGGN------------GGNGAYGCNGGNATGCARAARATHYTNGARGGN AAYYTNACNAGYGAYAGYGAYMGNGTNTTYCCNGGNGARGGNAAYACNACNAARGAYACN AGYAGYYTNMGNGTNATGGTNGTNGGNGCNACNAAYMGNCCNGAYATGYTNGAYCCNGCN GTNYTNMGNCCNGGNMGNYTNGAYAARCAYATHTAYGTNCCNCCNCCNGAYGARCARGCN MGNCARGCNATHYTNCARATHTAYACNTCNMGNATGTCNTAYACNGAYATHGAYGTNMGN YTNYTNGCNAAYAARACNGAYYTNTAYAGYGGNGCNGAYYTNAARAAYYTNTGYAARGAR GCNGGNYTNCAYGCNGTNMGNGCNCARYTNGCNAAYMGNGARTCNMGNCARAGYYTNACN GTNACNAAYCARCAYTTYATGYTNGCNYTNGAYAARGTNAARCCNTCNYTN--------- ------------------------------------------------------------ ------------------MGNGTNTGYMGNGAYAAYTCNTTYYTNACNACNAARYTNGAR GARMGNAAYGAYGARATGMGNMGNATGATHGCNCAYAARACNGCNATHGCNMGNGARMGN GAYGARYTNYTNGCNYTNYTNGAYGTNACNGARMGNATGAARTAYGARCARGGNAARAGY ATGATHGCNGARGARGARTAYGGNTCNTTYACNTCNACNGARYTNGCNGTNYTNGGNGCN TGYAARTGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYAAYCAYTAYTGGTAY ATGTTYYTNGAYAGYATHGTNAARGGNCARTGYATGAARACNGTNGGNAARAARATHATH TGYGAYCARYTNGTNGCNGGNCCNTTYTTYTGYACNATGTTYYTNTAYGGNACNACNATH YTNGARGGNAARGGNTTYTCNGGNGCNAARGCNGARTGGAARGCNAARTTYYTNCAYATH TAYATGATHGAYTGGGCNTTYTGGCCNGCNGCNCARTTYATHAAYTTYAARTTYYTNCCN ACNMGNTTYMGNGTNYTNTAYGTNAGYTTYGCNACNYTNGTNTGGAAYTCNTTYYTNTCN TTYATHAARCAYMGNACN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARGAYMGNGCNYTNGCNYTNAAR GAYCARGARGARMGNYTNGGNGCNYTNATHGCNTCNYTNCARATGGAYAARGCNMGNGAR YTNGCNAARATHGARGARCARCARAARGCNATHAAYAAYYTNAARTCNAAYYTNATGGAY GAYYTNAAYGCNMGNGGNGTNYTNTCNACNCCNGARTGYCARAARATHYTNAAYGTNCAY AARGARGAYCARGAYGCNATHAAYMGNAARYTNGAYGGNCARMGNGCNAARCARGARAAR GCNYTNMGNCARAARYTNCARCARMGNATGGARCARMGNGARCARTCNATH--------- ------------------------------------------------------------ ------------------------GARAARGGNATGACNGTNTTYYTNGAYGTNTTYMGN MGNGCNGAYAARAAYGAYGAYGGNTCNATHTCNTGGGARGARTTYGTNTCNTAYTTYGCN GAYGGNGTNATGGGNAARGARGARYTNCARACNYTNTTYAAYGARATHGAYTCNCAYAAY ACNGAYAAYATHGAYATHGGNGARYTNTGYGCNTAYTTYTCNCARCAYYTNGGNGAYTTY CARGARATHTTYGGNYTNGTNGARGARATGAAYAARAARATGACNGCNGTNYTNTTYAGY ACNTCNAARGTNTAYAARGAYTCNTCNMGNACNGAYAARTTYGTNACNMGNTTYYTNATG MGNGARATHYTNAAYCARATGGGNGCNYTNCARMGNCCNYTNGAYGCNGCNTCNGARGCN YTNGAYCARCARGCNMGNGAYGARMGNTCNGAYATHCARCCNYTNGARGTNGCNGAYATH ATHAARAARTCNGGNAGYGAYAGYGGNATHGTNCCNGGNMGNGTNGTNMGNMGNGCNAAR MGNCARGTNAGYAAYTGYAGYTCNYTNGGNGCNAAYGAYGARGGNCAY------TCNGGN CARACNAGYYTNAAYGGNCARYTNGAYAARYTNGCNMGNYTNGTNGAYAARYTNGARTGY AARATHAARTTYGARAAYTTYMGNGAYGARGARGTNGTNACNCAYGGNGAYGAYACNGTN YTNYTNGTNCARMGNGARTTYATHGTNAARGARGAYGGNATGAAYGAYTTYMGNTCNCAR YTNMGNTCNTAYGTNGAYYTNACNCARGGNTCNMGNGGNTGYTTYAAYGTNAGYGTNMGN GAYYTNMGNCCNAGYCAYTCNTTYCAYGTNTAYGARGTNTGGTGYGAYGARGARCAYTAY YTNCARAAYTGYGGNAGYGARCCNACNACNTCNYTNGTNAAYAARACNGCNGARYTNYTN GARAARCCNGARACNGTNAARTCNATGGTNATHCCNGGNTCNTGGTGGAGYYTNGARGCN CARATHATHGAYATHTAYCCNGAYTCNAARAAYCAYTAYATHAARYTNAAYGAYYTNCAY ATHGGNCARAGYTAYTCNGCNTTYATHGTNTGYGAYMGNACNACNAARACNAGYATHATH AAYTTY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNYTNTCNAARTTYGAR GCNGARGTNCAYAARATGCAYGAYGCNCAYGTNTCNYTNYTNGARTCNCAYCARAARMGN GARGCNYTNTGGYTNGCNATGMGNMGNAARYTNGARGARMGNATHCAYGGNYTNGARGGN TTYGCNCCNGGNGGNGGNGGNTCNCAYGGNGAYTCNTCNAARCCNATGTCNGTNACNGAR TCNGAYYTNMGNTCNMGNYTNYTNGARAARGARTCNYTNGTNGCNMGNYTNYTNTCNCAR AAYCARGARYTNGTNTCNAAYMGNAARCARYTNGARGCNGARAAYATHCARYTNAAYGTN ACNYTNGCNGARCARMGNGCNMGNGTNGARATHGTNGARAARGCNYTNGTNAAYTGYCAR GCNAARGTNYTNATGGGNGAYGARGARTAYCARAARAARATHTCNGGNGARGTNTCNGCN YTNGGNTGYAGYTCNTTYCAYGCNGCNGCNACNGCNGTNGAYTCNCAYGAYAARCARGAR GTNGARCARTTYGGNAGYGCNGGNGTNGAYCARAAYYTNGGNGTNGARGARAGYMGNGGN ATG------------------------------GTNACNGGNTGGAARGTNGAYYTNGAY TCNTCNTGYMGN------------------------------AARCCNACNTAYATGAAR GARGCNGCN------TCNGCNYTNATHGAYGARACNTCNCARCCNYTNAARGGNGTNMGN YTNGCNGCNYTNGARAARAAYTCNTCNGAYGTNGARAARYTNATHGAYGARGCNAARACN GARAARYTNAARCAYATGGARGARYTNCAYGARAGYAAYAARMGNACNGCNGARYTNGAR GCNAARGTNAARCARYTNCARACNCARYTNGTNGARAARGARGCNATGGTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYTTYGGNCCNTCNGCN YTNGGNACNCARGARTAYTGGGAYGAYGCNTAYGARAARGARYTNGARAAYTTYGAYGAR ATHGGNGAYGTNGGNGARATHTGGTTYGGNGARGAYACNCARAAYMGNATGGTNAARTGG ATGTGYAAR---AARTCNATHTCNAARTCNTCNAARATHATHGAYYTNGGNTGYGGNAAY GGNATGYTNYTNYTNGCNYTNMGNCARGARGAYTTYAGYGAYYTNACNGGNGTNGAYTAY TCNGARTTYTCNGTNAARYTNGCNAAYAARGTNTGYGARGCNGARCARATHAARGAYGTN ACNTTYGARGTNTGYGAYATHYTNTCNTCNTCNGAYGTNGARAARTTY------AARGAY ACNTAYGAYGTNTGYYTNGAYAARGGNACNTAYGAYGCNATHAGYYTNAARAAYACNAAR GAYCCNACNGAYMGNCAYATGTAYGTNGAYCAYGTNTCNTCNATGYTNAARCCNAARGGN CARYTNATHATHACNTCNTGYAAYTGGACNAARGAYGARYTNACNAARCAYTTYTGYAAR GCNTTYCAYYTNACNGAYGARATHCCNGCNCCNAARTTYACNTTYGGNGGNCARACNGGN CARAARGTNACNACNYTNATHTTY---------GCNCARATHATHATHTTYCCNGARAAY GGNATHTAYGGNTAYGAYTTY---TCNMGNCARTCNATHGARCCNTTYTCNGARCARATH CCNGARCAYGARAAYACNACNTGGTCNCCNTGYTCNAAYCCNGAYAARTTYGCNMGNAGY GAYGTNCARAARGCNYTNAGYTGYATHGCNAARGAYAAYAGYYTNTAYGTNGTNGCNAAY ATGGCNGAYAARGTNCCNTGYCARATHAARACNGAYCCNAARTGYCCNAARGAYGGNTTY TAYCARTAYAAYACNAAYGTNGCNTAYTCNCCNGAYGGNACNTAYYTNGCNAARTAYCAY AARGTNCAYYTNTGGTTYGARCCNTAYTTYAAYCCNTCNGTNCCNAARGTNTCNTAYTTY GARACNCCNTTYGGNMGNATHGGNYTNGTNATHTGYTTYGAYYTNYTNTTYAGYGAYCCN YTNATHACNYTNGTNACNGARCAYAAYGTNACNACNATHGCNTAYCCNACNAAYTTYGTN GAYTTYYTNCCNYTNGTNTCNGCNATHGGNTTYCAYTCNTCNGTNGCNCARGGNYTNGGN ATHAAYGTNYTNTCNGCNAAYATGCAYGAYGTNTCNTTYMGNGGNTAYGGNAGYGGNATH TAYACNCCNAAYGGNCCNAGYGARTAYTAYTAYGAYGAYMGNAARAAYTCNTCNGGNAAR YTNYTNGTNTCNTCNATHGAYAGYYTNTCNCARCAR------------------------ ---------------------------------ATGATGCCNAGYCAY------------ ------GARCARMGN------------GCNGAYGTNACNCCNATGATGCAYGGNACNAAR CCNGAYGAYTTYGARGTN---------------------------------------YTN ATHTTYGGNGAYATGTGGACNTTYCARYTNYTNAARGARTCNTCNGGNAAYGTNAGYGTN TGYAAYAAYAARATHTGYTGYTCNYTNAAYTAYAGYATHGGNGGNGAYTCNAAYGAYAAR GAYYTNTTYGCNYTNGGNGCNTTYGAYGGNYTNCAYGAYATGTTYGGNMGNTTYTAYTGG CARGTNTGYACNYTNGTNMGNTGYGCN---GAYAGY---AAYAAYAARACNTGYGGNAAR CCNGCNAARATHTCNTCNACNAARTTYGARTCNATHTCNATGAARGGNAAYTTYCARACN AARTAYATHTAYCCNCARGTNATHYTNTCNGAYGAYGARCARYTNMGNYTNCCNGARGAR AAYACNTGGAGYTTYGGNAAYAGY---ACNYTNGCNTGGGARTCNGGNYTNGARGARCCN GTNGTNAGYGTNACNATGATHGGNMGNGTNTTYAGYMGNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CCNCCNMGNMGNGAYATHACNTTYTGYCAY GAYTAYCARAAYAAYGGNTGYAAYMGNGGNAAYTGYAARTAYYTNCAYTGYACNMGNGAY GARCARGARTGGTTYCAYMGNACNGGNYTNYTNCCNYTNMGNYTNAAYCARCCNTTYGGN ---TAYGGNAGYCCNGGNCAYMGNGTNGAYGTNCCNYTNTGYAARGAYTAYYTNCAYGGN GAYTGYAARMGNGGNGGNAARTGYMGNTAYMGNCAYYTNAAYGGNGARTGY--------- ---AARMGNGGNGGNCARTGYAARTAYMGNCAYGTNATHGAYCAYGAYYTNGAYMGNGGN GGNACNATGAARMGNMGNMGNYTNGAYGAYGAYTAYGAYMGNGAYMGNTCNGAYYTNAGY TAYTCNTAYYTNGARGARGARAAYGARACNYTNAARAARAARGTNGAYGARYTNAARAAR CARGTNTCNGAYYTNACNGCNATH------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATHCARGTNMGNTGGMGNAGYYTNMGNTCNTGYTTY YTNMGNGARYTNMGNGARCARAARAARMGNATGTCNGGNCARGGNAAYAARAARMGNMGN AARTAYGTNTAYTTYGAYCARYTNYTNTTYYTNYTNCCNACNGCNGARGGNACNACNTTY AARCARGTNAARTGYCAYTTYATGAGYGGNTTYMGNAAYCAYGAYTTYCAYAARACNYTN ACNAARATGATGCCNAAYAGYACNTGGACNTTYAAYGAYYTNAARTCNGAYGAYAAYTAY AGYMGNGAYAARAARCARGAYATHAGYAAYGAYGARYTNAGYGAYATHACNTAYCAYYTN YTNAGYTAYTTYYTNYTNTTYAARTTYAAYTAYTCNGAYYTNGARATHCCNAAYCARMGN TTYAARGCNTCNTCNGTNYTNMGNAGYMGNMGNGGNAGYTGYTTYATHGGNGARACNGCN GARATHGTNGCNACNCCNTTYGCNTCNYTNTGYCCNGCNGTNTTYTTYAAYGGNTAYAGY MGNGGNGTNATHAGYAAYGTNGCNGGNGTNAAYGAYTGYTGGATHGTNTCNGAYGCNMGN TGYATHCCNGGNTGYGARGGNGGNCCNYTNTAYACNAARMGNAARCCNACNGAYAARGAY AGYTTYYTNACNGGNATHATHACNTCNCCNYTNTGYTGGAARAAYAAYGARTGGGTNGGN TTYTCNGTNGCNTGYAGYATHGAYAGYATHYTNATGTCNATHGCNCARAAYCARGARATH YTNCCNTAYGGNAGY------------------AAYAARTAYYTNACNTCNGGNACNGCN ---MGNAARGARAGYAGYCCNYTNGAYAARAARYTNYTNAAR------GCNCARGCNGTN ACNGTNYTNGTNCARTGYGGNAGYACNTGGGGNACNGGNGTNATHGTNAAYMGNGAYAAR GGNATHATHYTNACNTGYAGYCAYGTNATHAARGGNGCNAAYCAYTGYTCNGTNACNGTN ACNCCNTCNAARAGYACNAAYCARCAYMGNGGNCARGTNATHTAYMGNCARGARCCNGTN MGNACNGCNTAYGAYYTNGCNGTNATHAARTGYCCNCARGCNACNAARCAYYTNCAYMGN GGNTGGTGYATHAGYGTNGCNCARGCNTGYGTNGGNGARGAYGTNYTNYTNTCNGGNCAY GCNGTNTTYGGNACNGAYAARTAYYTNGARCCNTCNATHTGYCARGGNGTNGTNTCNAAR GTNATHMGNATHCARGGNGARCCNGTNATGGTNCARACNACNTGYGCNGTNCAYGCNGGN TCNAGYGGNGGNCCNYTNYTNACNTCNGAYTGYMGNYTNGTNGGNATHGTNGTNTGYAAY ACNMGNGAYTCNGTNAGYAAYACNAGYTTYCCNCAYGTNAAYYTNTGYATHCCNATHTCN ACNGTNTGGCCNATHGTNCAYAAYTAYYTNTGYGGNGGNGAYAARGARGGNYTNTCNCAR YTNCARGTNAARGAYGTNGARYTNAAYAARYTNTGGGCNYTNGGNGCNCARACN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CARTCNCAYMGNTAYCARGAYYTNGAYAAYCCN GCNTAYAAY---AARTCNTCNYTNGGNGTNCAYCAYGTNCCNAARATGCAYATHTCNAAY ATHAARTCNGTNGARGCNGCNGGNATGMGNCCNGTNACNTCNTCNYTNACNMGNTCNMGN CCNGCNCCNYTNCARCCNMGNGCNCCNCCNGGNGCNGCNACNYTNTCN------------ GCNAARCARCCNATHGCNYTNTCNCARCARTCNTCNTCNGGNGCNATHAARMGNMGNCAR CCNCCNGAYATGCARGARGTNGGNGGNCCNYTNMGNYTNGGNAARGGNGGNGGNCCNGGN YTNCARGTNGGNATHGGNGARGTNTCNCCNCCNAARMGNGCNAAR------CCNGGNGTN CAYCCNTCNGARCCNATHGARATHTTYGAY---GARGAYAAYTCNAARTTYGTNAGYCCN ATHCARGGNTTYMGNGTNGTNGTNACNAAYYTNTTYTCNGGNGTNACNCARGAYGAYATH ATHGARYTNTTYGGNGTNGTNGGNCCNYTNAARAARGCNMGNYTNYTNAARGCNGGNTCN GCNGARGTNGTNTAYACNGTNMGNGARGAYGCNYTNAARGCNGTNCARAARTAYCAYGGN MGNGARYTNGAYGGNCARCCNATGTAYGTNAARATGACNACNCCNTCNACNGCNGTNGTN AARACNCCNYTNGGNCAY---GAYCCNGAYATHACNGGNGARGCNYTNMGNYTNTAYAAR AARCCNAGYAGYYTNGGNGCNYTNCCNGARGCNCCNATHGARGTNCCNACNATHCAYMGN GCNYTNTTYAARGTNGGNCCNCCNGCNCCNAAYAARTCNGTNAARTTYACNGTNAARATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNYTNGARGAYTAYAARGCNCARAAYCCNGAYAAYYTNAAYGCN CAYMGNTAYYTNTAYGARTTYGARATHAARCAYAARGARAARATHGAYGGNGARYTNCAY AGYYTNCARAAYATHATHMGNYTNGAYCCNAGYCAYCCNYTNGCNATHAARYTNTAYMGN GAYYTNATHTCNTCNGAYCCNGARGCNGTNTCNATHYTNTTYGAYTAYYTNGAYTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARAARTCNCCNGARTGYTCNACNTGYAARGARATHGTNGAYAAYTTYCAYAARGGN YTNACNGCNACNGCNAARTCNAAYTAYGGNGGNGGNAAYACNAAYTGGGARGARAARTCN YTNGGNTCNTAYGCNTTYAGYGARGTNMGNYTNGTNGARATHGTNGARAAYYTNTGYAAR GAYAARTCNAARGARTGYCAYACNATGYTNGARGARCAYGARGAYYTNGTNGARAGYTTY TGGTTYAARGARTTYGCNAARAARTCNGAYAARGAYTTYCAYACNTTYYTNTGYATHGAR AAYATHAARGCNTGYTGYCCNAAYAAYACNTAYGGNAARGAYTGYYTNCCNTGYCCNGGN GGNGTNGARMGNCCNTGYCAYGGNAAYGGNAARTGYCARGGNGARGGNACNMGNGGNGGN ACNGGNAARTGYMGNTGYAGYGCNGGNTAYGCNGGNTCNYTNTGYCAYGAYTGYAARGAR GGNTAYTAYCARGARAGYAARAAYGARACNCAYAGYGTNTGYAARYTNTGYCAYATHTCN TGYAARGGNAAYTGYTCNGGNGARGGNCCNMGNGCNTGYGAYGARTGYAARGAYGGNTGG GTNGCNGAYATHACNAAYGGNTGYAARGAYATHGAYGARTGYYTNGARGARCCNTGYGAR GAYGAYCARTAYTGYACNAAYACNYTNGGNTCNTAYTCNTGYTTYACNTGYAAYACNGCN TGYACNTCNTGYACNGGNGCNGGNCCNGAYAARTGYAAYGAYTGYAAYAARGGNTAYATH AARYTNGAYAAY---GARAARTGYGARGAYCARGAYGARTGYAGYYTNGAYCCNACNYTN TGYACNAARTCNAGYGARGARTGYATHAAYACNCCNGGNAGYTAYGARTGYATHTGYACN ACNGGNTAYGARTAYAAYGARGAYAARGARTGYATHAARACNCCNAARGAR--------- ------------------------------------------------ATGGGNGGNACN GARAGYAARMGNMGNATHGTNGTNGARGAYGTNAAYGGNGARGGNGTNGTNCARGTNACN GAR---GCNGTNGTNMGNMGNATGAARGGNCARCCNGCNCCNCCNGTNCARAARACNTCN AAYGARYTNCCNMGNGARAARGARTTYTCNAAYACNGARCAYMGNCCNCCNMGNGAYGAY GARMGNTAYMGNACNATGAGYAARGARATHGARGAYTTYTAYATGGARAARYTNAAYGAY YTNCARAARAARAGYCAYGCNYTNCARCARCAYTCNAAYGARCAYTTYTCNAARGCNGTN AARGARGTNGARGARAARTTYATGAARTAYACNACNTCNCCNGTNTGYCARGAYATHCAR ACNAARGTNYTNGARTGYTAYCARTCNAAYCCNGAYTCNATHYTNGAYTGYTCNTCNGTN GTNAAYGCNTTYACNACNTGYGTNGAYMGNGCNMGNATGACNGTNTCN------------ ------------------------------------------------------------ ---------------------------------------------GCNTAYCARCAYGCN CARACNYTNAGYAAYCAYGGNTAYATGATHMGNGCNTGYGCNTTYAAYYTNGGNGCNATG ATGATHTCNGCNAAYAAYTAYATHGARGGNYTNTCNTAYYTNAAYAARGCNATHCCNCCN AAYGGNAARMGNGAYGGNMGNTCNAAYGGNGAYYTNTAYTTYAAYTAYGGNYTNGCNTAY GARGGNYTNAARAAYCCNAGYAARTCNAARTAYTAYTAYGARATGGCNYTNAARGARTAY MGNGCNGARAAYGAYAAYGTNAARATGGARGCNGAYACNATHACNMGNATGAGYMGNYTN TGYGTNGARAAYAAYYTNYTNTCNGARGCNAAYGAYYTNATGAARCARYTNACNGTNYTN CAYTCNAGYCARGGNGAYGTNGARAARGARYTNCARTCNMGNGTNGARMGNTCNAAYYTN YTNYTNAARATGGGNMGNGCNCARGARGCNGARGARGTNGCNGAYAARTGYTTYAARGTN YTNGARAGYAAYACNCCNTCNYTNGCNTTYGCNAARATGTAYAGYGAYYTNTCNGTNGCN TAYACNCARATHYTNCAYTAYGAYAARGCNGTNCARTGYAAYGARAARGCNYTNCCNYTN GTNGARGAYTCNAGYGGNGAYCCNMGNYTNGCNTCNGTNATHTAYCARAAYYTNGGNGCN ATHTAYAAYTAYATGGGNMGNTTYGARGARGCNGTNAARTTYCAYGAYAARGCNTGYCAR ACNTTYGCNAARYTNGGNATGMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARCARGAYAAYATHYTNGARGAYGAYMGNTTYAGY AARCAYATHGAYCARGCNMGNAARYTNGGNTTYTCNGARGARCARACNTCNAARGTNYTN MGNMGNYTNGGNGTNGAYGCNAGYATHGAYGAYATGATGMGNGARTTYGTNTCN------ ---------------------------------------------------------GAY CCNCARGGNYTNAAYGARYTNGAYGAYGAYAAYAAYYTNTCNTCNAARGGNGARGAYAGY GAYGAYAGYGGNTTYGAYGTNAAYGAYAGYTCNAAYYTNMGNCCNATHATHATHGAYGGN AGYAAYGTNGCNATGAGYCAYGGNCARAARGTNTTYTCNTGYYTNGGNATHAARATHGTN GTNGAYTGGTTYAARAGYMGNGGNCAYAARAAYATHATHGCNTTYGTNCCNYTNTGGMGN AARGARGCNTCNMGNCCNGAYGCNCCNATHACNAAYCARGARATHYTNTCNGARYTNGAR GCNGARAARATHGTNGTNTTYACNCCNTCNMGNMGNATHGGNGGNGCNMGNATHGTNTGY TAYGAYGAYMGNTAYATHYTNGARTGGGCNGTNAARACNAAYGGNATHGTNGTNTCNAAY GAYGTNTTYMGNGAYYTNGARMGNGARMGNGAYGAYTTYAARGARGTNGTNGARAARMGN YTNYTNATGTAYTCNTTYGTNCARGAYACNTTYATGCCNCCNGARGAYCCNYTNGGNMGN CARGGNCCNTCNYTNGAYAAYTTYYTNMGNATHAARCCNTCNGARCCNAARAAYAARCCN CARATHTGYCCNTTYGGNAARAARTGYACNTTYGGNATHAARTGYMGNTTYTAYCAYCCN GARMGNMGNTAYTCNTCNCARAARATGGTNGCNGARAARYTNAARGARAGYGCNGARYTN AARYTNAARYTNAGYAARGARACNGTNACNGARAARGGN---AARCCNAARCARAARYTN TCNMGNACNGTNTCNYTNGTNCCNCARGGN---GCNAAYAAYGAYGCNACNTAYGAYGGN CARACNAARAARCCNCCNYTNCAYCAYTCNAARTCNYTNGTNTAYCCNAGYAGYTAYYTN ACNGGNYTNMGNYTNAARATGGARACNGTNYTNCARTCNTCNTTYGCNACNATHCCN--- ---MGNCARGAYGTNAAYCCNGAYCARACNCAYACNTCNGCNGCNGTNAARAAYCCNACN AARACNCARTAYTGYAAYCCNAGYCCNMGNACNTCNCCNACNCCNGTNCAYAGYTTYCCN TCNTCNCCNATHCCNAARYTNCCNCCNGGNTCNTCNYTNAAYATHCCNAAYTCNGARTCN CARAAYMGNTAYYTNAGYGGNCAYYTNYTNGTNGTNAARAARYTNTCNGAYGARGAYAAY AGYAAYTTYTTYTCNAARCAYACNTCNGARGGNAAYCARGCNGTNAAYAARGAYAAYATG MGNTTYACNGAYGAYGAYTAYMGNAGYATGGAYAAYTTYYTNGCNGAYCARATGYTNAGY AARTCNMGNGARAARATHATHTCNMGNAAYGGNGTNAARTAYACNGTNCARGTNTCNCCN YTNGARATHGCNGAYYTNGCNCAYCCNTCNYTNCARCARYTNATHCAYYTNCAYCCNACN ATGTCNYTNATHTTYAARMGNCARACNGTNAARTTYAARAARAARAARGGNTAYGCNGAR GCNGCNTTYTCNACNATGACNGARGTNAARGARTTYGTNTAYCARYTNACNCARATHAAR GTNTTYGARAARMGNATHGAYGTNACNATHACNGTNYTNAAYCARTCNGAYAAR------ ---YTNTCNTTYGTNATHAAYYTNAAYMGNAAYGAYAARYTNYTNAAYYTNYTNGAYTCN GGNGARGAYCCNYTNATHAAYAARCCNATHCCN---------ATHGGNGARAAYCCNCAY CARGTNCARGTNCCNAGYAGYGCNAAYGGNGCNTTYATGCAYAGYATGTTYCCNTTYACN AAYAAYGTNYTNATHACNMGNACNCARGTNGGNAARGAYGGNAARACNGTNTAYCAYGGN CCNGTNTCNGTNTTYTAYATHAAYTCNAARTGGGTNGARGCNGTNATGGAYTGYTGYTCN GARTTYTCNGTNAAYGAYTTYCCNYTN------ACNGCNATHGGNGAYYTNAARAARGTN AAYCCNGTNGAYAARMGNGGNACNACNAAYGARYTN---------------------GAY CARAGYTCNAARTCNTTYGTNAGYGTNGGNGARGGNAGYGGNGAYTAYGAYGARGAYGAY GAYCCNATHTCNAAYATGACNMGNGAYGTNTGYGCNGAYATGYTNGARTCNGTNCARAAR YTNMGNGAYYTNGARCCNAAYAAYCCNAAYATGAARAARATHGTNGARATGCARAAYAAR YTNAGYATHYTNCARAGYTCNYTNAARMGN------------TCNMGNAGYTCNACNACN GCNAGYGARCARGARACNTTYTCN------------------------------------ CAYGARATGAARYTNAGYCCNGCNGARAARAARCARMGNGARYTNAARAGYGTNGARGAR AARTTYGARGARGCNGARMGNYTNGARCARCARGARGARGARCARATGAARCARMGNMGN GARYTNGAYYTNCARAARMGNMGNGARTCNGARCARAARAARAARTCNCARTGGGCNAAR AAYGTNYTNTCNGAYTTYAARAARCARGARGGNGTNGTNGGNGARMGNATHAGYGCN--- ------GAYGCNAARAARATHYTNCARCARMGNGARCARMGNATH--------------- ---------AARGARMGNGARGARGARGARMGNCARMGNAARGARGARGARATHMGNAAR CARGARGARGARGARAARYTNMGNGTNCARCARGARAARGARGAR--------------- ---AARTTYMGNGARGCNGARMGNAARMGNYTNATHGARAARATHGARGARGCNMGNTCN MGNGAYTCNCARAARTTYTCNTCNTCNCARYTNCARTGGAAYCCNTCNTGYAARATHCAR AARAARGCNYTNCCNTTYTCNYTNTCNAGYMGNTCNACNGARMGNGAYTAYTCNTCNGAR MGNGARGARTGYCARGAYGGNYTNATHATGTCNGARGARGARTAYCARGAYYTNGTNGGN CARYTNCAYACNATHCCNAARAAYYTNAARGTNTGYATHACNAGYYTNGCNAAYMGNYTN TGYCCNGTNCARGAYTGYCCNTCNAARACNCAYTTYMGNAAYATGGARYTNTTYATGGAY CAYTGGGTNATHTTYCAYCARTCNCARACNACNATGMGNTTYTGYCCNMGNTGYTCNGCN TAYTTYATGAAYCCNGARGARYTNGARAAYCAYATHATGAARCAYCAYTGYYTNTCNTCN ---AARGARGCNATHGARYTNGTNMGNAAYGCNMGNACNAARGTNATHGCNAAYCCNAGY TAYMGNGAYCCNTTYCCNTTYYTNCARTCNAARTAYGGNATHCCNGTNYTNMGNGAYTTY TCNAGYGGNGTNAARCCNYTNTCNAGYMGNGARAARTTYGTNMGNCARATHYTNACNGAY MGNGARGARGARTTYACNGAYYTNAARACNTTYAARGTNTTYTGYGGNTCNTGGAAYGTN AAYGGNCARTCNCCNGCNGARGCNYTNCAYAARTGGATHGTNGTNGAYAAYGARCCNCCN GAYATHTAYGCNATHGGNTTYCARGARYTNGAYYTNAGYAARGARGCNTTYATHTTYAGY GAYTCNGTNAARGARGARTGGCARAAYGCNGTNAARAGYTAYYTNCAYCCNAARGCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ACNCARTTYYTNMGNATGTAYGGNMGNCCNGTNAARATHCAYYTNGAYCCNGCNGTNGCN ATGGCNGCNGARGGNCCNCARAGYATGATGGCNTGGCARGGNGAYAAYACNAAYATGATH GAYMGNTTYGAYGTNMGNGCNAAYYTNGAYTTYATHACNGARTAYAAYCCNAAYMGNYTN TCNAGYACNTCNAAYGTNAAYGARCAYGAR---GARMGNYTNGCNAAYTAYGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MGN ACNTGYYTNAAYGAYGTNTCNAARATHATHTCNYTNGCNYTNATHACNGARYTNCCNTCN ATGGGNGARATGGGNMGNTTYCCNGAY------------YTNGARACNGARAARYTNMGN GGNGARYTNTCNGARYTNCARTCNAARTAYAGYGTNYTNCARTCNACNGTNAARGARCAR CARGGNAARYTNAAYGTNTCNAARCARMGNCARMGNGAYTGGGARCAYTCNGTNTGYMGN CAR---------AARAGYAARMGNTCNMGNAGYYTNTCNGARTCNTTYGAYGAYYTNAAY GCNATGGARAARGARYTNGGNGARGCNTCNGAYGAYMGN------------GARATHATG GAYTGYMGNGAYGTNGAYCCNGARAARATGGCNCAYTTYAAYAAY---MGNATHYTNAAY CCNGARCAYACNGCNCARTAYGARCARATHAARMGNGCNTAYGCNAAYATHYTNTAYAAR TGGGGNYTNYTNAAYCARMGNGCNCARATHYTNAARCAYACNGTNTCN---YTNCARAGY TGYAARAARATHGARTTYTCNATHCCNTGYTCNAAYTGYTCNGAYGCNGTNATGAAYGTN CARTGYAAYMGNTGYMGNTAYCCNTCNYTNAAYTGYTCNATHTGYCAYGTNGGNGTNMGN GGNCCNGCNAAYGTNTGYYTNGCNTGYGGNCAYGGNGGNCAYTCNAGYCAYATGAARAAY TGGTTYCAYAGYAAYAAYCARTGYCCNAGYGGNTGYGGNTGYAAYTGYYTNCARGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATH GAYTGYYTNCARTCNGARAARACNCAYYTNTGYGGNGARATHAARAARYTNAAYGAYCAR ATGTGYTGYCARYTNGARCARYTNAARAARATGGARACNGAYAAYCARGARYTNTGYMGN CARYTNCARCARAARATGGARTGYATHMGNGAYYTNGARAAYYTNGTNMGNACNAARGAR CAYGARYTNAARTGYYTNACNAARTAYGTNCARGAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNGTNMGNTCNYTNYTNCARTCNCAYGGNCARAAYGGNGGNCAY GGNTCNTCNTAYGGNAAYGGNGGNTAYGGNTCNGGNCAYGGNGGNAGYGGNTTYGGNGGN TAYGGNGGNAGYCARYTNGGNAGYTTYGGNATHCAYYTNCCNAGYCARGTNMGNTAYGGN CAYTCNTAYGCNCARTCNCCNATHATHTCNTTYGTNAARGGNTTYAARCCNGGNAARATH TAYGTNGAYAAYGGNCAYGTNGTNMGNAAYTAYTTYMGNCAYGGNACNTAYAAYGTNGCN YTNCARCAYTAYAARYTNATHCCNACNGTNAARGTNATHCCNTAYACNACNTAYAARAAR ATHGGNGTNGGNCARMGNGTNCARGCNAARTTYMGNTAYAARGCNGTNATHTGYAARTAY TGYTAYCAYGGNTAYCCNAARATHGAYGTNTAYGARATGAARAARCCNTAYAGYTAYGCN ATHMGNMGNTTYGTNTAYYTNCCNAAYGAYTAYAAYYTNAAYAGYTAYGGNGGNAGYTAY GCNGGNGGNCARGGNTAYGGNTAYGGNGGNCARGGNCAYGGNTAYGGNGGNCARGGNTAY GAYGGNGGNAGYGTNTCNGGNTTYGGNGGNMGNGGNTAYGGNCAYGGNGGNAGYTAYGGN GGNAAYAGYTAYGGNGGNTAYGGNTAYGGN------------------AGYGAYAGYACN GCNYTNGCNGTNGTNYTNTAYAARGARACNGCNYTNYTNCCNCAYGARAARAARAAYMGN AGYTTYAAYATHGCNGGNAAYAARTTYTAYATHGARCARGAYTGGCAYGCNGGNGGNGTN GCNGCNGTNGTNTGGGAYGCNGCNATHGTNYTNGGNGARTAYYTNGCNTCNAAYGCNCAY YTNGTNCARGAYAARMGNGTNYTNGARYTNGGNGCNGGNACNGGNYTNGCNGGNATGGTN GCNTCNTCNYTNGGNGCNGAYGTNATHGTNACNGARMGNGARCARGCNYTNTCNTTYYTN GARACNGCNATHTCNGCNAAYAARGCNGAYAARAAYTGGAARGTNAARGCNGARGTNYTN GAYTGG---ACNCAYGAYATHGAYTCNTCNAAR---TGGAGYMGNTTYGAYATHGTNATH GGNGCNGAYATHGTNTAYATHGARAGYACNTTYTCNCAYYTNYTNAARACNATHAARTCN GTNGCNAAYTCNCCNCARACNCARGTNYTNYTNTCNTGYMGNATHMGNTAYGAYMGNGAY YTNGTNTTYYTNAARATGYTNAARAARTTYTAYAARGTNGARGARATHTTYTAYAAYTCN AARYTNGAYATHAARATHTTYTCNGCN------------YTNGTNACNCAYTAYGGNGGN TGYCAYTGYGGNGCNGTNMGNTTYTCNGTNAARGCNGCNGCNCAYYTNGAYGTNGTNGAR TGYAAYTGYAGYGTNTGYYTNAARAARCARAAYCAYCAYTTYATHGTNCCNAARTCNMGN TTYGARYTNYTNCARGGNTCNGAYTCNYTNACNACNTAYACNTTYAAYACNCAYAARGCN AARCAYACNTTYTGYAARGTNTGYGGNGTNCARAGYTTYTAYACNCCNMGNTCNAAYCCN GAYGGNTAYGGNATHATGCCNCAYTGYGTNGAYCCNGGNACNGTNCARTCNACNACNGTN ACNMGNTTYGAYGGNAAYCARTGGGARGCNTCNATHAARACNTCNAAYATHGCNGARTAY TCNAARAGYCCNTCNTAYYTNGTNTTYGCNTAYGGNACNYTNAARMGNGGNGARCCNAAY GARTGYGARATG---GGNCCNGARTGGGGNMGNGCNGARTTYYTNGGNTGYGGNGARACN AARGCNAARTAYCCNYTNGTNGTNTAYACNTCNTAYAAYGTNCCNTTYYTNATGCARGAR GARGGNCARGGNTAYAAYGTNMGNGGNGARYTNTAYMGNGTNGAYGAYAARATGYTNGAY CAYYTNGAYTAYTTYGARTTYCAYCCNCAYYTNTAYGTNMGNAARGARGCNGARATHACN YTNACNAARGAYGCNCARGGNAAYGAYGTNACNCCNCCNCARACNMGNACNTGYYTNGTN TAYTTYYTNTCNMGNMGNCAYGAYGARATGYTNAARYTNCCNTAYMGNCCNGARTAYAAR TCNGTNGAYGARGGNAAYYTNCCNTAYGTNATGMGNGAYGARMGN--------------- ------------------------------------------------------------ ---------GTNTTYMGNAAYACNACNAARGGNGARCARTGYGAYTGYGAYCAYGTNGTN MGNCCNYTNMGNCCNAAYYTNTCNTGYTCNYTNTGYCARTGYAARACNGARACNMGNAAY ACNACNACNATHAARGTNGTNGTNATHTTYATHATHTGYGTNGTNTCNYTNYTNTTYGTN TAYATGYTNTTYYTNYTNTGYYTNGAYCCNYTNYTNCARAARMGNCCNGCNAARTCNTAY CARCARCAYACNAAYGARGARGTNAAYATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNCCNCCNGARATHGAYGGNTTYGARAAYCCNGTNGCNYTNCAYGGNGGNGTN GAYGGNYTNGAYYTNGTNMGNCAYATHYTNTAYCARGCNCARACNYTNGTNGTNCCNAAY GGNCAYYTNTTYYTNGARGTNGGNGARAGYCAYCCNGGNYTNATHGARAAYTTYGTNGCN AAY---AAYCARACNYTNAGYYTNCARTTYATHAGYGGNAARAARGAYATGTTYGGNMGN AAYMGNTTYTGYCAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AGYYTNTTYGAYACNACNACNAAYGARYTNAAYMGN ATGATHAARGAYATHYTNGAYAARYTNAAYGGNCAYGARGARGGNTGGAARTCNGCNYTN GCNAARGCNATGGARGARYTNGAYGGNAARYTNGAYMGNATGGARYTNMGNAAYYTNAAR GAYTGGYTNGARAARCARYTNAARGCNATHAAYAAYAARATHAARACNATGGGNCCNGGN TTYCARYTNGAYGAYGARGCNGCNGGNATGAARAARCARYTNATHCARMGNTTYAAYTGY YTNTCNTGYGAYAARCCNGTNGAYGTNATGCCNCAYGGNCCNATHCCNTCNATHCCNGGN AAYTAYGGNYTNCCNMGNTCNAARTCNCCNMGNCCNTAYACNACNTTYGARYTNGAYCAR ATHMGNCARCAYGCNMGNAGYYTNGGNATGAGYCCNGARYTNGCNGAYTAYTAYGCNCAR GCNMGNCARTGYGGNGGNCAYCAYACNATGACNTAYCCNAAYAARMGNACNACNAARYTN AAYAAYYTNGGNCARGTNTTYMGNGARGARGARACNATHYTNCCNYTNTAYAARGAYGAR ATHGAYGTNCARGGNGCNGAYGGNCAYATHTAYAARGGNMGNATGGARTCNGCNMGNYTN GARGCNAARYTNCCNGTNAAYYTNACNACNAARCAYTCN---CAYCCNGTNTAYATGGAR ACNAARGCNCCNTCNCCNCCNCCNGCNCARMGNCCNYTNTCNGCNMGNYTNCCNMGNCCN GGNTCNGCNMGNCCNGGNTCNTCNAAYTCNCARCARMGNTCNCARTCNGCNATGCCNATH CCNAAYGGNGAYGCNGTNGTNGTNCCNCARAAYAGYCARATHGGNGGNTCNMGNGCNACN ACNCCNATGCARGARGARGCNGARGTNGCNGTNGAYYTNGTNGCNGTNGARAAYMGNGTN CARGARGARGARCARYTNGAYGARMGNGCNGARCARGARGARAAYGTNATGTTYAARAAR CARAARTCNAARGTNYTNCARAAYGGN------GARTAYGTNGAYAGYCARGCNAGY--- ACN------AGYAAYGARAAYYTNTCNTCNAGYACNAARGARAAYAARGAYACNGTNGAY AARATHYTNCAYCARMGNGTNCAYTTYCARGTNTAYTAYYTNGGNYTNGTNCCNGAYATH AAYYTNACNAAYTCNAARAARMGNGAYACNGARGCNCARYTNATHGAYGTNGTNGARGAR AAYCARATHGARGGNAARYTNCARGTNACNGCNACNGAYGARAAYAARGTNGTNATGAAY ATHTCNMGNCAYGGNATHAARGTNYTNGAYATHGCNGGNAARGARGTNYTNCARMGNCAY CCNYTNCAYACNATHGCNCARYTNACNGARTAYAAYGAYGGNTTYAGYMGNCARAAYATH GCNGTNAARATHGGNCARGTNGGNAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYACNTCNTGYGTNATH YTNGGNTCNGCNATHYTNTTYAARGARTTYTTYAARATGGAYGCNATGAAYGTNATHGGN GAYYTNTGYGGNTTYYTNGTNATHGTNATHGGNATHTTYYTNYTNAAYTCNTTYAARGAY YTNAARATHTCNYTNMGNAAYYTNCCNAARGCNTCNAARGARGTNGAYGCNGAYATGYTN GARGGNATGGAYAGYAAYAAYTGYMGNGAYATHGARGCNGGNTAYAAYTTYMGNYTNAAY GTNTCNGTNGCNGARCAYYTNCCNGTNACNGGNGCNTCNYTNMGNGTNGTNATHATHGTN TCNTTYGCNGTNGGNGCNGGNTTYGTNYTNTAYAARTAYGCNAAYCAYYTNTCNATGGAR TGGGGNGARGAYCARMGNGARGARACNATGGAYMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TCNCCNATHGGNGCNGAR ACNAARCCNYTNATHYTNACNACNGCNACNTCNGCNACNTCNCCNATHCCNYTNACNAAY YTNTCNGCNAAYTCNATGAARCCNAGYMGNTCNAARCCNTCNACNCCNGCNACNACNATH AARCCNTGYGTNTTYCCNYTNACNGARGCNGARTCNGTNTGYCAYGARGTNGAYATGTCN GAYATHATHATHCCNCCNCCNATHAARACNGARGAYGTNCCNYTNCCNCCNGGNAGYCCN AARACNCCNGCNGGNGAYCARGCNAARYTNGAYAGYCARATHGTNGARGAYYTNACNAGY ATHYTNYTNCCNAAYAAYCCNCCNCCNTTYGGNAARAGYTTYTCNAARGAYACNATGGAR YTNGGNAARGCNAGYGTNTCNTTYTCNTTYCAYAARACNACNAAYAARATHGCNACNACN TCNGCNTTYAAYCARGARGARCCNGAYCCNGTNGARGTNCCNCCNACNMGNCCNYTNACN YTNATGGAYAGYATHGARGARGARAARMGNYTNATGGARCARGARTCNCARCARAAYYTN GARACNACNACNGAYAARAARCCNGARGTNCCNACN------------------------ ------------------------------AARCCNMGNYTNYTNGARAARTTYGTNCAR GTNGTNYTN---AARGARGGNACNGGNGARATHCCNTGGCCNGTNGARACNATHAARTAY ACNAGYACNCARCCNAGYATHCAYTTYGCNTGYAAYYTNATGCARTTYGAYTTYAARGAY ATHATGAAR---------------ACNGARACNACNACNGCNGCNGGNGAYGCNGTNAAR AARGGNGARGARGTNAAR------------GCNGARAARGAYAGYAARGARGGNAARGAR AARAARAARCAYTCNTCNMGNAARAARMGNAARMGNAARAARGGNAGYGGNAARGGNGCN GAYAGYAARAGYGTNGARGGNACNAARGTNGARAAR------GARGGNGARAAYGARGCN ATHGARTGYGARCCNGGNGARAAYAARAARGAYAARAARAARAARMGNAARAARMGNAAR AARMGNCAYAARAGYAARAARGARGARGGNGARGCNGGNGGNGAYGCNAARGARGGNGAY GGNAARGGNGARGAYAARGAYAARTCNMGNMGNMGNCCNCAYMGNAARMGNACNCAYAAR GARMGNGAYGARAARGCNTCNGARAARGTNAAYGCNGGNYTNGGNAARGARAAYACNGAR GAYGTNYTNGTNAAYGGNAARAAR---------AARGARYTNTCNTCNTCNACNGGNAAR MGNAARCAYAARMGNAARCAYMGNMGNMGNMGNCAYGAYMGNTCNGARAARGCNAARGCN ATGAGY------------GCNTCNGARAARAARACNGTNGAYACNGTNAAYGCNAARGAR CCNAARGTNAARATHGAYTAYGAYGAYGARGARGARACNCAYATHCCNACNGAYAAYGAR CARGAY---ACNGCNGARCCNAARATHAARMGNCCNTGYMGNTCNMGNAARMGNCAYMGN MGNAAYAGYAGYCAYAARCAYAAYGARATGGAYTCNYTNAARTCNGARGAYMGNAGYGGN GCNGAYCARYTNAAYATHACNTTYAARACNCAYAARAARATGCARGARAAYGCNATHAGY AAYYTNCCNGAYATHGTNAARGGNGTNAGYGCNGGNACNAAYAARYTNACNGGNCCNTCN AARGARAAYGAYACNCARCAYTCNAARACNCCNAAYGGNGAYATHAGYAGYGGNMGNAAR MGNGGNACNAGYATHTCNAGYACNGAYGGNACNACNCCNGCNAARGTNAGYAARATGGAY AGYAARGCNGTNGARGARGAYACNTGGAGYAARATGGARGGNYTNTAYGARGAYATGGGN GARGARGGNTCNAARAGYAARTGGGAYACNAGYGAYAGYGARGGNGARGAYGCNYTNCAR AARACNYTNGAYGCNAAYGGNGAYAARGCNGGNAGYAGYGGNAAYACNAARCAYMGNGAR YTNCARCARAARCCNACNAAYGGNAARATHCCNYTNTCNAARTCNATHYTNYTNACNAAY ---------GGNATGAAYCCNATGAARCAYCAYACNYTNTCNACNAAYCAYAGYAAYCAY ACNACNTCNAARCAYGAYAGYACNGARAARGGNGTNGGNGARGAYGAYAARTCNAAYTCN ------------------ACNCAYAARCARTCNTCNTCNGCNTCNCARMGNGARGGNMGN TCNMGNAARMGNGGNAGYMGNMGNTCNTAYACNTCNTCNGARTAYTCNTCNCAYTCNMGN TCNTAYTCNMGNTCNMGNTCNGGNTCNTAYMGNAGYTAYTCNGAYGAYTCNMGNTAYAGY GAYTCNAGYMGNTCNCAYAGYMGNTCNTCNMGNAGYTAYAGYMGNAGYMGNTCNMGNCAY MGNTAYMGNMGNMGNTCNTCNTCNAGYMGNGGNMGNAGYMGNAGYTAYAGYTAYAGYAGY MGNAGYAGYTCNAGYMGNTTYMGNTCNMGNTCNTAYTCNMGNTCNMGNAGYTAYTCNMGN TCNMGNTCNMGNGGNMGNGGNTAYCAY---AGYAAYTCNMGNAGYCCNTCNMGNMGNAGY AGYGTNAARYTNAARMGNATHYTNAARTCNCCNYTNGCNATHGTNCCNGTNACNACNYTN ACNGTNGCNCCNGTNACNGGNTGYACNGTNGGNGGNGTNAARGAYAGYGCNACNACNAGY GGNGGNGGNGGNGGNGAYGGNAGYGGNGGNGCNACNCCNGAYGAYATHCCNYTNCCNGCN AARGAYGCNTCNTCNGCNTCNACNTCNACNAGYCCNAARAARGAY---GARGAYAARTCN GTNYTNACNGAYATHCCNYTNCCNACNACNAGYAARYTNACNACNGCNGAYGGNAARGAR AAYTCNAAYTCNGGNGARAGYTCN------------------------------------ ------------------------GCNGTNGTNAAYAAYAAYGGNGAYCCNACNACNTCN GCNCCNGCNGTNGCNATHCCNTCNGAYTCNCAYACNAAYGGNAAYCCNAAYACNGAYCCN YTNAGYAAYCCNATHMGNGAYGGNAAYATGACNGGNGARAAYAAYGGNGGNGAYATGYTN GGNTAYGAYCARGAYTCNTAYAAYCARATGGGNTAYGGNAAYCAYGAYTCNGCNTTYTGY GARGAYACNGGNTAYGAYAAYTTYGARTTYGAYGGNGGNGGNGAYTAYGAYCARCAYGGN GGNGGNTAYGAYGAYCAYCAYCARGAYTAYGAYTAYAAYCCNGAYCCNTAYCAYCAYCCN CCNYTNMGNCAYCARGGNCCNCCNCAYGGNCAYCAYATGMGNGGNCCNCCNCCNYTNGGN TAYMGNGGNCCNCAYCCNMGNATGTTYCCNCCNGAYATGMGNTTYGGNCCNCCNMGNCCN GGNATGGGNCCNCCNMGNATGMGNCCNCCNAAYGGNCCNATGGGNCCNCAYCCNCCNATG GGNCCNMGNGGNCCNMGNCCNCCNATGGGNYTNGGNGGNCCNATGGGNCCNCCNGGNATG MGNGGNCCNCCNCCNMGNGGN---CCNCCNMGNGGNCCNCCNGGNATGMGNGGNCCNCCN GGNATGCCNGGNCCNMGNGGNCCNCCNCCNMGNCCNGGNATGATGGGNCCNCCNCARGGN GGNCCNATGGGNCCNAAYGGNCCNMGNCCNMGNATGGGNYTNGGNCCNCCNMGNATGGGN CCNCCN---CCNGGNCARGGNCARGGNCCNATGCCNCCNCCNCCNGGNGGNCCNMGNAAY MGNATGCCNCCNCCNGGNCAYATGCARGGNCCNATGMGNGGNGARGGNCARCCNCCNCCN CARMGNCCNGGNATGCCNCCNCCNGTNMGNGGNCCNATGCCNCCNCAYATGMGNGGNCCN YTNCCNCCNAAYATGGCNCAYCCNCCNCCNAAYTTYAAYATGCCNCCNCCN--------- ------------TCNTCNTCNTCNGARGGNATHAARCCNCCNGARTCNATGGARCCNCCN CCNYTNCCNCCNCCNAARGCNCCNACNCCNCARCCNCCNCCNCCNCCNAARAARGARGAR GARAARAARGARGARATHAARCCNATGGTNCCNGAYATHCCNCCNGARCARGCNGARCAR TAYMGNAARYTNMGNGARAARGCNCARAARCAYGCNAARAARCARCARMGNAARGCNGAR CAYCARGCNAARGGNGARCCNGARAGYAGYGAYGAYGAYGAYGAYGARGARGCNGCNAAR AARAARGARGAYGCNGCNAARYTNGCNGCNGARCARAARGARATGGARGARGCNGCNYTN YTNGCNGCNCARGGNGGNGARAARGTNGCNGTNGARGARGGNAGYGCNATHYTNGTNCCN TCNCCNACNACNCCNYTNGCNGTNCARCARCARGCNGTNTAYATHCARCARCARCCNATH GCNGCNGCNGCNGCNGCNGCNCAYTCNACNTAYGGNATHGTNTCNACNCCNCAYYTNGTN CAYGCNACNCAYCCNGCNYTNCARGCNGGNCAYCCNCAYGCNCAYGCNCAYGCNCAYGCN TTYGCNGCNGCNGGNCARCCNCARYTNGTNCARYTNCCNAAYGGNCARGTNGCNTAYGCN ACNCCNGCNMGNCCNCARTCNGTNCCNYTNCARGCNGGNGCNCCNGTNATHGCNATGTCN CAYCAYGCNCCNATHGCNGCNGCNTCNCCNTCNATGTCNCAYCARYTNYTNYTNCARTCN GGNGCNGTNCCNGGNCARGTNCARATGGCNCAYGCNGTNCCNGGNCCNCARTAYATGTCN CAYGTNATGGCNGCNCARGCNCARGCNCARGCNCARGCNCAYGCNCARGCNCARGCNCAR ATGCARGCNGCNCARGTNCARGCNGCNCAYATHCARGCNGCNCAYGCNCARGCNGCNCAR GCNCARGCNCARGCNCARGCNCARGCNCARGCNGCNCARYTNCAYGGNYTNGTNCCNGCN GGNATGCAYGCNGCNCARCARATGYTNCARGGNGGNCARCCNGGNCARCCNCARGGNCAR ATHATHYTNGTNCCNMGNATHGCNMGNCCNCAYATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGNGCNAARTTYGAYATHGGNGCNAAYGARATGYTN ATHACNCCNYTNGTNGARTAYCAYGCNGARGGNTCNTAYCAYTTYCAYAAYCAYGTNGCN GTNAARYTNCCNCAYGCNYTNCCNGAYGAYTTYGAYGTNTCNYTNATHAARTTYTAYACN TTYACNMGNGAYGAYTGYGGNAAYGTNYTNYTNGARTCNYTNCCNYTNAARTTYAARGAY AAYAARAAYATGGAYGAYGCNTTYTGGGARATHTGYAAYCARGGNMGNAGYTTYATHGCN ACNAARCAYTTYAGYGGNTAYTTYTGYACNACNTGYGARAGYAARTCNAARYTNCCNTCN GTNTAYGCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHAARYTNGARGGNAAYTAYTTYATHATGGAYTCNGARCARYTNGTN TCNAAYCCNTTYCARGARYTNCARCARGARGCNGTNAAYGARGCNAAYAARAARAAYAGY ATGACNGARAARYTNACNATHGTNAARAAYAAYGTNTGYGARAAYCAYTTYCARATGGCN AARAGYAGYYTNGARMGNCARMGNAGYAGYAARYTNAARCARYTNCAYGAYCAYGCNAAY AARYTNMGNCAYGARGTNAARYTNYTNGAYYTNGAYMGNCARMGNCAYACNGTNGARGTN MGNAARMGNYTNGARCCNGARAARGAYTAYAGYTAYGAYGARGTNCARATHCAYAAYACN GARMGNMGNYTNGGNGCNAAYATHGCNTCNTTYTAYYTNGAYAARAARYTNAARTAYCCN ATGMGNYTNMGNTCNATGAARGAYATHMGNGTNACNCCNACNATHTCNAARGCNMGNGCN AARATHMGNACNAGYGAYGTNAAYAARGCNYTNGARGARGARATHAGYTTYTCNMGNCAR GAYMGNGCNCARACNGCNAARACNACNGCNTCNGCNAAYACNAAYACNAAYAGYGCNGCN MGNMGNMGNGGNTCNMGNTCNGCNCCNYTNMGNAAYACNMGNTCNAARACNYTNTTYCCN GCNATHGCNGGNYTNACNMGNAGYAARACNTTYACNAARGGNGGNAGYGCNACNGGNCCN CARCAYCARGTNAARTTYACNTTYGARAAYCCNYTNAARATHYTNGCNTCNAGYGARGAR AGYGCNAAYATGTTYGCNMGNTCNTGYTCNTAYTAYCCNGGNTCNACNMGNGCNATGGAR GCNAAYAARATHTCNMGNYTNMGNGARGARCARCARAARGCNGTNTCNGARACNGARGAY ACNATGGARCARYTNGARMGNTAYAARGCNGAYTAYAARGCNYTNCARAARMGNYTNGAR ACNYTNCCNGAYAARGTNACNCAYGAYGTNATGGTNCCNTTYGGNAARYTNGCNTTYATG CCNGGNGARYTNGTNCAYACNAAYGARATHATGGTNYTNYTNGGNGAYAAYTGGTTYGCN GARCARTCNGCNAARCARGCNCAYGGNATHGCNGCNMGNMGNATHAARGARYTNGARAAR MGNYTNACNGARATHGARGARCARAARMGNYTNYTNGARCCNMGNYTNGGNATHACNTCN GARYTNCAYGCNGTNGCNGARGGNAARGGNGAYTAYAARGAYATHATHGARGAYTAYAGY GARGARAARGARMGNYTNTGGGAYGARCARCAYAARATHTTYGTNMGNMGNCAYAAYGAR AAYMGNMGNGTNAARYTNGCNAARAGYGCNACNTCN---------------------GTN TCNMGNCAYAGYGAYGARGAYYTNTGGTCNMGNYTNGAYGCNYTNGARAARCARGARATH GARMGNGGNGARYTNAAYAGYTCNTTYGARTCNGAYAGYAAYACNGARGAYGTNAGYGGN CARGGNGARGARAGYGAYTGYCARMGNAARMGNAAYYTNTCNYTNGCNMGNGAYAARMGN GTNATHTGGATG---------------GAYGARAARGAYAARAAYAAYGARGTNTGYAAY GARTAYCAYAGYGAYGAYAAYGAYACNGAY------------------------------ AGYGAYTAYGARGTNAARCCNATHATHAARACNATHACNTTYCARCAYACNAARGCNCCN ACNYTNYTNCCNCCNGARGGNAAYCARGARTTYAAYATHACNAGYCCNGCNGARATHTAY AARYTNTTYTCNCCNAARCCNATHYTNAARAARATG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GCNGTNACNYTNYTNCCN GCNATHYTNATHATHAGYATHACNATGATHGTNGCNACNATHGGNAAYGTNATGGTNTTY TAYATHTAYCARACNAARTTYAGYGCNAAYTCNACNMGNACNGCNGTNYTNGCNYTNGCN YTNTTYGAYYTNYTNGCNAGYTGYTTYTCNATGCCNGGNGARATHATHGAYYTNMGNTAY TCNTAYAAYTTYMGNAGYGAYGCNYTNTGYAARTGYATHMGNYTNGGNACNACNGTNGTN YTNATHGCNTCNGGNYTNACNYTNYTNATGGTNGCNGTNGAYMGNTAYMGNMGNATHTGY CARCCNACNAARGAYCARTGGACNGCNGARCARACNAARAARGGNGCNYTNYTNTGYYTN TGYGTNGCNGCNGTNYTNTCNATHCCNTCNGGNATHGTNTAYGGNYTNTCNAARGTNGAR GGNGTNTAYGGNACNGARTGYTCNATHGAYCARAARTAYCAYAAYCAYATHYTNCCNYTN ATHAAYAAYATHYTNCARGCNYTNATHTTYGGNACNGTNTTYTTYACNATHATHGTNYTN TAYAGYYTNYTNGGNMGNGTNGTNYTNMGNCARAGYAARTTY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYGTNGTNATHGGNTAYCAYGAYGAYGAYYTNGAR TTYGTNMGNAARYTNGCNACNAARYTNMGNTCNAARGGNYTNAGYGTNTGGTAYAAYGAR CCNGGNGAYGAYGGNAARAARACNAGYGARGCNATHYTNGGNTGYAARGTNTAYYTNCCN GTNYTNACNGARYTNTCNGCNGTNGAYAARGGNATHCARGARCARYTNTCNYTNGCNTAY ATHTCNAAYTCNGCNATHTAYCCNYTNGGNAARATHMGNTTYAAYYTNYTNGCNCCNAAR YTNAAYGGNGGNGCNMGNYTNATGYTNGCNAARATHAAYTGGTCNTTYATHYTNAARGAY GARCAYTTYGARTCNMGNACNGAYACNATHATHGARTGYATHCARAARGAYATHAARAAY ATHGARAARATHTTYGAYACNTCNGCNGARAGYTCNGGNTAYGTNYTNACNCAYGGNATG CARGTNCCNATHAGYACNAGYCAYYTNCCNAAYCCNGGNGAYCAYGARCCNGARTTYGTN GCNTTYAGYCARGGNATHGAYYTNAGYTCNATHAGYCARGAYACNCCNTTYTGGGAYMGN CAYTTYAARGGNAARAAYGARGTNACNTGGATHGARTTYMGNGAYAARTTYYTNCARGAY TAYGCNGCNAARATHGTNGARGGNTTYTCNGARAAYGGNGARGARMGNAARAARATHTTY GTNAAYYTNATGTAYAARGAYGTNTTYATHYTNAGYAARACNGTNAARMGNTCNGTNTAY GAYAARTTYTGYGGNAARCCNCAYCCNCAYGCNTTYTTYATGGGNATGCARGAYTAYGTN ATGGCNTAYGTNTCNYTNMGNGARGTNYTNAGYATGGAYAGYAGYYTNMGNATHCCNACN ATHCARAAYYTNGGNMGNTTYMGNTTYCCNGCNATHGTNTCNGGNYTNTCNGAYATGATH GARGAYGAYGAYCCNAAYGTNMGNGCNGTNGCNGCNATHGCNYTNGCNCAYGCNGGNAAR AARAGYGARTCNACNGTNGAYAARATHATHAARYTNYTNGARGAYGARGAYMGNYTNGTN MGNGARAGYGCNTGYYTNAGYYTNGGNTAYYTNMGNTCNACNMGNGCNGTNYTNCAYGTN GTNGAYMGNTGGMGNAAYGAYCCNATHTCNACNGTNMGNGARGCNGCNGARYTNGCNYTN AGYMGNATGGAYGCNCCNGAYGCNGTNCARTGYATGAARGTNACNAARGTNYTNTCNTCN GARATGAAYGCNYTNAARCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------GTNGARAARGCN GGNGCNGTNTAYMGNTGYAARACNGAYAARGTNAAYTCNTGYCARCARGTNCCNTTYGAY ACNAARGGNAAYAAYATHAARTAYAAYMGNACNYTNGGNAAYTAYTCNCCNATHGARGAR AARTCNAAYCARTGGTTYGGNGCNACNYTNCARAGYTCNGGNGARAGYGGNGTNATHGTN TCNTGYGCNCCNMGNTAYATHTAYTTYGGNAGYGAYYTNMGNAARMGNGARCCNGTNGGN ATGTGYTGGGTNGCNAARACNTCNACNACNGARTAYGARAAYTAYTCNCCNTGYATHGAR GAYATHGARAARATGATHGARMGNTGYGARMGNAARATHGAYGARYTNGARMGNAARAAY MGNYTNGTNGARATGTCNGAYGARCARTGGCARGARYTNAARAGYGARAARAARYTNYTN GARAARCARATHAARACNTAYAARAGYGARYTNMGNGGNYTNMGNTGGCARAAYTGGAAR AGYATGGTNATGTCNGTNTGYATHTTYGGNYTNYTNTAYGTNGTNTAYGTNGTNGTNTTY GAYTCNGARTCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARMGNMGNMGNTGYGAYTCNGGNAGYTCNGGNATHACNTCNGAR GAY---GGNGAYTGYGAY------------GAYAAYGAYAAYTAYTAYGAYAGYGAYGAY GAYAAYTCNGAYYTNGAYGCNGAYYTNGCNCAYATGAARCCNGGNGGNTGYGARTCNYTN ATHGGNGGNGGNAARAARCARAARCARTAYTTYTGGCARTAYAAYGTNCARGCNAARGGN CCNAARGGNACNMGNYTNAARYTNGCNGTNGARTCNCCNGCNGAYCCNCAYATHYTNAAY GGNTTYGARGAYCCNGTNTTYGAYGARGGNAAYACNACNGTNGCNGGNATHMGNCAYGGN GGNAARGCNMGNAARGGNGAYGGNAAYGARGTNAGYCCNAAYCCNCAYAARYTNTTYAAR ATHGGNCAYCARYTNYTNMGNYTNAAYAARAARATHAAYGGNTGYCARYTNGGNTCNGAY GTNCCNYTNGCNCARMGNAAYGARGCNMGNAARGARAARAAYAARYTNGCNTCNMGNGCN TGYMGNYTNAARAARAARGCNCARCAYGARGCNAAYAARATHAARYTNAAYGGNYTNGAR ATGGARCAYGGNCARATHAAYAAYGTNYTNMGNYTNYTNTGGCCNGARYTNMGNGARMGN GCNAARTGYYTNCARAAYGARCAYCAYGTNGARGAR------------AARCCNYTNCAR GAYAGYYTNTTYAAYAARYTNAAYGGNTAYATHACNTCNAAYATGAARAGYATGGTNGCN GGNCAYACNACNGAYTAYGTNAAYAAYGTNATHATGAAYGTNGARAARGGNGAYYTNACN GGNGGNYTNAARGGN---AARGCNMGNAARACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARGAYYTNAARAARATGAARGTNCCNGARYTNAARCARGCN YTNAARGARAARGGNYTNTCNACNTCNGGNGCNAARACNGAYYTNATHAARMGNYTNGTN GARTCNGTNGARGCNTCNGGNGAYAGYAAY---GAYCCNGTNYTNGAYGAR--------- ------GAYGARATHYTNAARGAYGAYTCNACN------------------ACNGTNGTN GCNGCNCCNACNGCNGCNGTNCCNAARGCNCCNGCN------------------------ GARAARTCNGARGCNGCNAGYAAYGGNGTNGCNTCNACNAAYYTNGARCCNACNCCNAAY GTNAARATGGCNGCNGAYACNACNGTNGTNGCNAARCCNACNGARGTNAARAARATGACN GAYGCNGARMGNYTNAARYTNMGNGCNGAYAARTTYGGNGTNACNTCNGARCARGCNAAR AARNNNYTNMGNGCNCARMGNTTYGGNATHGCNYTNTCNGARAAYAARTCNGGNAAYATH AGYTCNTCNACNGGNCCNGTNGAYGTNGAYAARYTNAARAARMGNGCNGARMGNTTYGGN GTN------------TCNACNAGYTCNGTNACNGARGAYGARAARAARMGNAARMGNGCN GARMGNTTYAAYACNAGYYTNACNACNTCNACNTCNTCNAARAGYGTNAGYYTNAAYTCN ACNGAYAGYGARYTNGARGCNAARAARMGNAARMGNGCNGARMGNTTYGGNYTNACNACN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARGTNAARAARGCNGTNGTNTTYTGYGAYAARAARATGGCN MGNGTNYTNCAYTGGATHGGNGGNATGGCNACNYTNYTNGAYGCNGGNGCNGARGAYGTN MGNGARTTYTCNTCNTTYGARAGYGGNGCNGARGAYCARAARAARGGNGTNTTYYTNGTN AGYGAYCCNYTNGARGGNGTNACNGARACNATHYTNCAYGAYATHYTNACNCARAGYCAY TTYCARTAYGTNATHGTNYTNACNACNGCNCAYCCNYTNYTNCAYTCNAARATHACNGCN GCNAGYATHGARAAYGGNGCNGCNTTYGARTAYTTYGARGARCARYTNYTNGARTGGATG GGNAAYATGAAYTAYACNTCNGARGTNCARCARATHAAYATGTTYAGYTGYGARATHTCN CCNGGNTTYTTYATHACNCCNGCNTTYTCNGARYTNTTYCCNYTNYTNCCNTCNGAYYTN CARCARATHAAYTAYCAR---CARGGNATHMGNYTNGTNAARGAYGGNAARAAYTGYGAY GGNYTNAAYGAYGTNGARATHACNAAYYTNCCNGARGAYYTNGARATHCARATHMGNATG TTYTCNACNTCNYTNGAYGGNYTNYTNYTNTCNATGAAYGTNAARGARGARATHTAYTCN ATHGGNTGYYTNAGYMGNATHATHGCNACNGAYYTNGAYAGYTTYCCNCCNGCNAARGTN MGNMGNAARACNTGYCARTCNMGNATGTCNYTNYTNYTNATHGAYMGNAGYYTNGAYYTN GCNACNGGNGTNACNMGNCARGCNGAYGTNYTNYTNGAYAARATHTTYAAYGTNYTNCCN TCNYTNGGNAGYAAYGAYTGYGAYAARYTNGTNGAYATGACNGAYYTNTGYCAYTGYTAY AAYACNAARTCNAGYCARAGYGTNATHYTNCCNGGNTGYYTNGCNCCNTCNAARATHAAR GAYTCNTCNTCNCAYYTNACNGCNACNATHATGAARAARCARAARGARGCNYTNATGGAY ATHAAYMGNMGNYTNGTNGARACNGCNATGTCNGARAARYTNCCNYTNGAYYTNTCNMGN MGNCCNAGYMGNGTNACNGCNGAYYTNYTNGAYTCNACNYTNTCNYTNTTYAARGGNAAY TAYTCNYTNATHCARAARCAYYTNGAYACNYTNCARGTNGCNATGGCNACNAGYCARGCN YTNAARCAYCCNTCNGCNCCNCAYCAYGAYGGNGTNATHGCNAARGARAARAAYYTNYTN CARGCNATHGCN------------------------GAYGGNGARGARGARGGNGARAGY AGYGCNTAYCCNTCNGCNTTYTCNYTNYTNTCNAARYTNTTYATHACNGARYTNGGNAAR GAYAARGARGARMGNGARTTYACNYTNGAYGAYATHYTNCAYYTNYTNGTNTAYATHTAY TCNGTNTCNAAYGGNAGYAGYGARAAYCARGARGARGTNMGNGTNYTNCARGAYTAYATH GTNCARYTNATHATHAARGAYAARGARTGYYTNCCNCCNATHATGAARGCNATHGTNGGN GAYAARGTNACNGARTCNATHYTNCCNGAYCARATHGARAGYATGTGGGARAARYTNGAY GGNYTNATGGARGTNMGNMGNGAYATGACNGAYTTYGGNAAYYTNYTNGAYCCNGGNTGY GAYATGAGYCCNGCNTCNGTNAAYCCNYTNYTNAARCARGTNATGGARMGNATHGTNGAY CCNGCNMGNCCNGARATGCCNGAYGTNGARTGYAARTCNGGNGGNYTNAARGAYYTNYTN AARTCNGGNTTYGGNTTYTTYAARAGYACNGCNAARCCNMGNCCNGGNGAYGCNCCNYTN YTNATGGTNATGGTNATHGGNGGNGTNACNGGNTCNGARGTNAARATGATHAARGAYATH GTNAGYAGYGCNAARCCNGGNTTYGARGTNGTNATHGGNGGNACNMGNATHAAYAGYACN GARGCNACNYTNCAYTCNYTNYTNGTNGARGAYAAYATHAAYATHAAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GTNGTNATHAAYMGNGARGGNTCNAAYGCNAGYAAR TTYATHTAYGARTCNGAYGTNYTNACNAARTAYMGNGARAAYATHGTNYTNGTNAAYGAR TGGYTNAGYYTNGAYATHAGYTCNACNAARATHMGNMGNGCNTGYMGNMGNGGNGARAGY YTNAARTAYGTNGTNCARGAYGCNGTNATHGAYTAYATHAARGARCAYMGNYTNTAYGGN YTNCCN---ATHATHAARATHGTNAARGTNYTNGARAAYCCNGTNTTYCAYTTYAARTGY YTNACNATHYTNGGNMGNYTNYTNYTNYTNGTNACNACNGTNTGYYTNTAYAARMGNTCN AAYTGYYTNCARMGNYTNGTNGARATGGCNGGNGTNCCNGTNYTNAARGARAGYTGYCAY TTYCAYCAYAGYYTNYTNYTNTCNCARYTNCAYGGNGAYACNATGGARGARGAYMGNATH GTNACNGTNGARGAYGTNGTNTGYYTNTTYYTNGCNACNTTYCARCARCCNGTNAARCAY YTNGTNATGGARCAYAARMGNTGGAARTGGYTNTTYGCNGGNATGGARTGYMGNAAYYTN ATGYTNGAYAARTCNCAYGCNYTNGCNATGCARAARYTNCARGTNGTNYTNAARGAYTGY GTNGAYCCNCARCAYAARAGYMGNYTNYTNTGYYTNTTYGCNGAYTGYTAYTTYCAYYTN GAYTGYCCNCARYTNTCNATHCARACNTAYMGNGAYGCNYTNCARACNGAYTCNMGNCAY TTYTCNATHATGCAYMGNYTNTCNCAYGTNTAYCARAGYYTNGAYYTNCCNGARYTNGAR YTNGARTCNYTNAAYYTNTGYGTNATGGCNYTNTCNCARGAYGARMGNMGNGARGGNGAY MGNATHCCNGTNATG---GAYYTNGAYGARYTNATHTGGTCNACNGTNCCNCCNYTNYTN GAYATHTCNTAYGTNATGGCNAARGTNACNTTYGCNAARMGNTGYYTNCARYTNAARMGN TAYCCNGARGCNGCNGARCARTAYTCNAGYYTNATHGGNATGYTNYTNCARGARGAYATG TTYYTNCARTTYGARAARCAYGARATHAAYCARGARYTNAAYATHGCNGARATHATHGTN GARGCNGCNGARGTNYTNGTNATHACNTGYCARTAYCARGAYTGYATHAARYTNTGYGAY AAYACNCARCCNTCNYTNTCNGCNGAYGAYACNATHGCNACNAAYAGYCARTCNYTNACN AAYGTNGARAAYTCNCARTCNGAYATHTTYCAYYTNYTNGAYAARTCNCARAGYYTNGAR AAYTAYGAYCCNYTNTCNTGYTCNAAYAAYGGNYTNATHTCN------------------ ------------------------------------------------CCNAARGGNGGN AAY------CAYTCNTCNGCNGAYYTNTCNATHTCNTTYGARAARTCNMGNAARMGNGTN MGNTCNAGYGGNAAYMGNGARGAYGTNAAYGARATGYTNACNGARAGYAGY--------- ------------AAYGAYATHYTNATGACNMGNYTNYTNYTNAGYAARGCNGAYGCNYTN ATHYTNTCNCARGGNTTYACNGAYGAYGCNATHTAYTGYYTNCARAARTGYATGGAYATH YTNATHCAYCAYCCNYTNTCNATHCAYAARYTNTCNTAYCCNACNCAYCCNCCNTAYTCN AARMGNCARMGNATHAGYTCNGAYGGNAARGCNGTNCCNCARGGNYTNGAYAAYGGNCAR TCNGGNTTYTCNGARGTNTCNAAYAGY---TGGTTYMGNYTNYTNGTNGAYACNGCNYTN MGNATGGCNACNGCNTCNTAYAARMGNAARMGNTTYTCNTCNGTNATHAAYAGYTGYMGN GTNGTNGARCARYTNGAYAARGGNAAYATHGTNGCNGCNTAYYTNTGYMGNGAYCARCAY YTNCCNGAYGGNGTNCAYCCNCAYCCNTTYGARAAYMGNAARTTYATHGTNTGYGCNTAY CCNGTNACNGCNATHMGNAARTGYCCNTCNGGNTTYCARTAYGAYGCNMGNTCNATGGCN TAYAGYGCNATGCCNTGYAGYMGNAARGGNGCNTGGTTYCCNTCNATH------ATHGGN GTNCARACNYTNTGYAARGAYTTYGGNYTNTCNAAYGARAARTAYCCNCAYCCNTTYYTN TGYGAYAARTAYATHCARTGYAGYAAYGGNYTNACNAAYGARATGCCNTGYGCNCCNGGN ACNAARTAYGAYAAYGAYYTNCARACNTGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNYTNYTNTGGTCNCAYAGYGAYAAR TTYYTNAAYCARTTYCARGCNAAYYTNCCNYTNTGYCARTAYMGNCCNTTYAGYYTNTTY CCNATGAARTTYGTNCAYGAYYTNAGYTTYTGGGARMGNGAYTCNGTN---ACNGAYTTY GAYGTNTTYGGNYTNTAYGARGCNATHMGNAGYGTNGTNGGNGAYYTNGTNACNAGYGTN TCNYTNATHGAYATHTAYGARGAYAARGARATGAARMGNMGNAGYMGNTGYTAYMGNYTN CAYTTYYTNTCNTCNGAYAARTGYYTNTCNTAYGTNACNTCNTGGAARATGCARAGYAAR ATHMGNATGGARGTNGCNMGNAGYYTNGGNGTNCARYTNMGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ACNCCNYTNGGNGGNCCNGAYGTNTTY AAYGTNTTYYTNAARGCNTAYATHGARCAYTTYAARTAYAARTCNACNTAYACNAARGAY TGGAARGARTTYYTNYTNAARTAYTTYTCNYTNGAYGARGAYCARAARAARYTNAAYAGY GTNGAYTGGGAYGCNTGGYTNTAYGGNGARGGNGTNCCNCCNTTYAARCCNAAYTAYGAY CARAGYTTYGCNCARGCNAGYYTNGAYYTNAGYGARMGNTGGATHAAYGCN------AGY AGYGCNGAYAARTTYGCNCCNGARGAYATHAARAAYATGAARGGNGAYYTNGTNAARGAR TTYGTNTCNMGNYTNYTNATGGCNGARCCNCAYATHTCNAARGAYAARGTNGARCARYTN GARTCNATHTAYAAYTTYAAYGCNGTNAARAAYTCNGARATHMGNTTYACNTGGYTNGAR YTNTGYATHCARGCNCARTGGATHGAYTCNATHCCNCAYATHYTNAAYTTYYTNAAYGAR CARGGNMGNATGAARTTYGTNATHCCNYTNTAYMGNTCNATGAAYAARTGGGARGCNGGN MGNAARCCNGCNYTNGARAAYTTYGARAARCAYAARGCNGARATGCAYAGYACNACNGTN AARAARGTNGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GCNATHYTNCARCAYAGYATHGAYTAYATHACNTCNYTN GARAARGAYCARAGYMGNYTNCARATGCARYTNGARMGNACNGCNMGNYTNYTNGCNGAR YTNGGNCARCARGAYMGNGTNYTNGTNGAYTCNTTYGTNACNAAYACNCCNCCNCCNTCN AARMGNAARAARMGNGAYACNGARTCNTCNGAYGARGGNGTNGGNTCNYTNTCNGAYGCN TCNGAYGAYTGYGGNACNGAYYTNMGNCARAARAAYGARGARYTNMGNMGNGARATGGAY MGNGARAARCARMGNGGNGAYTCNYTNGARGARGARAAYMGNAGYYTNMGNAAY---YTN ATHYTNATHCARAARCAR---CARMGNGAYCARCARACNGTNACNYTNGTNGCNGCNCCN CARCARCARGARATGMGNGTNMGNGAYGCNGTNGARGTNATGTCNCCNMGNYTNAAYTAY ACNCCNCCNACNACNGCNMGNCCNGCNTCNCCNGAYAGYACNATHACNATGGCNGCNACN ACNCCNCCNATHAAYACNGGNMGNTCNATHATHTCNTCNGARGTNCAYATGGAYCAYMGN GAYACNCCNTCNTCNYTNATHAGYATGTCNCCNGCNGCNTCNTCNGAYTCNGCNTTYYTN CAYAAYTAYGCNCAYMGNGAYCAYCCNMGNMGNMGNCAYCARACNATGGAYAAYCAYGAR GARACNYTNGAYGCNYTNACNGCNTTYGGNAARAAYCCNAAYCCNCARGARATHCCNTCN GTNYTNGARCARTAYYTNAAYTCNGTNGCNAARAAYGGNGARACNYTNTTYCCNTGGACN CARYTNAARCCNYTNATHYTNMGNAARATGGARYTNGTNATHATGGARYTNMGNMGNAAY YTNGCNTCNGARAAYATHCCNACNMGNCCNAAYGTNGARAAYGTNMGNTTYGAYGTNATH CAYGCNMGNATHATHGAYTCNYTNCAYAARTTYAAYGGNGCNCCNTTYACNATHCARMGN YTNTGYGARYTNYTNATHGAYCCNAARMGNCAYTAYAARMGNAGYGAYAARTTYATGMGN GGNYTNGARAARAAYGTNYTNGTNGTNAGYACNGTNGAYCCNTTYGGNMGNAARGTNGTN TCNGARYTNGGNAAYAARCCNGTNYTNAAYGGNATHYTN---GAYATHAAYGGNTCN--- TAYCCNCCNMGNGAYTCNGCNYTNAGYGTNCCNYTNCCNCCNGTNCCNGGNTGGGTNAAY ACNTCNGCNGCNAAYMGNAAYGCNGGNACNGGNGTNATGTCNCCNTCNGCNGTNGAYGGN GGNAAYAARACNGGNCAY---------------AAYATGGAYACNYTNGAYAARGAYTCN GAYGGNATGGTN------TCNAAYAGYATGGCNGTNGCNGGNACNCARCCNYTNGCNGTN CAYTCNGARGARGTNGTNGARGARACNGTNGTNACNATGGAYACNGGNGARGTNAGYTCN GTNGTNACNGAYGGNGGNGARGCNYTNGCNGAYMGNGAYATGGARGGNGGNGAYGTNGAY MGNGARGAYMGNGAYGCNTCNTCNTCNTCNTCNTCNTCNTCNTCNTCNTCNGARGARYTN TCNACNTCNTCNGAYTCNGTNGARAAYAGYATGGCNACNGGNAAYMGNYTNAARGARGAR GTNACNGCNATGGAYGARAAYMGNCCNTGGGCNGCNTTYGCNCARGAYATGAARCARCAR CARGAYGAYYTNGGNACNACNTCNYTNTCNTCNTCNTCNACNTCNTCNTCNCCNCARYTN TCNTCNGCNGAYCCNTCNCCNYTNTCNTCNTCNTCNTCNTCNYTNTCNCCNGARACNCAR TCNTCNYTNCCNTCNGCNTCNAARACNACNTCNATHTCNACNTCNAAYGTNGARGARGAY MGNCARGARGAYAGYCCNGAYGGNGCNGARTGYGCNCCNACNAAYCARCARACNACNGTN TCNTCNGAYCARTCNGAYTGGCARCARCAR------CARTCNTGYGAYGARTCNTCNTCN ATH---------GCNGAYACNAAYCARAGYTTYGGNTTYGARACN---ACNACNACNACN CCNACNCCNTCNTCNCCNCARCAYATHGCNGAYATGACNACNACNTCNGCNACNACNGCN ACNGAYAARYTNATHTCNTCN---------TCNACNAGYACNGTNATHCCNACNTCNACN GTNACNACNACNACNACNACNACNACNAAYAAYAAYAAYAARAAYACNTCNTCNTCNTCN GAYATHCAYACNTCNTCNCCNTGGACNGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATHAGYGAYGAYTTYYTNCARGTNTTYGTNTTYATHGAYTAYGCNATHYTNTCN GGNATHATHTCNTTYTCNGGNYTNGTNTCNAAYATHATHAAYATHATHATHTTYTAYMGN YTNGGNTTYAAYGAYACNGTNAAYATHTCNYTNTTYAGYYTNGCNYTNTCNGAYTTYGGN GCNYTNYTNCCNATGGTNTGGAARGCNATHYTNTTYAAYCCNTCNTTYCAYAAYTGGGAY YTNACNTTYGAYTAYATGACNTTYCARTAYTAYACNGGNGGNTGGCCNCAYGGNTGYTTY GCNAAYTTYTCNGGNYTNATHATGTTYTTYGTNACNYTNGAYMGNTGYYTNTGYATHGCN ATGCCNYTNAARGTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNCAR ACNCARTCNGGNATHYTNACNAAYAGYTCNGCNTCNACNGGNAGYTCNACNGCNACNYTN GTNACNATGGTNACNGCNYTNCCNGCNTCNTCNACNAAYACNACNACNACNACNAGYGTN ACNGGNTCNTCNCARGTNGCNGTNTCNACNGGNTCNAAYATGYTNTCNTTYCCNGTNGGN YTNAGYGGNYTNACNCARYTNATGCCNGTNACNTCNAARGGNCARGCNGGNCARACNATH MGNCCNACNGCNATGCCNYTNYTNCARYTNCARGGNCARCARGGNATHCARYTNYTNAGY YTNCARCARMGNGGNCARGTNAARCARGGNACNAGYAGYTCNAAYACNGCNCARGGNATH ACNMGNYTNGCNCARGCNGGNACNACNACNGTNCCNYTNTCNACNGTNYTNGCNGGNCCN CARATGACNGCNYTNGGNATGGGNAAYAARCARGGNCARGGNGGNAGYACNGCNATHACN GCNCARCARYTNATHCARYTNACNGGNGGNCARGGNGCNTCNYTNGGNCARGGNGCNGGN CARMGNGCNGCNCAYATHACNTTYGGNAARGGNCARCARGGNYTNCARTTYCAYTCNYTN CARYTNAARCARGGNGGNGCNACNYTNTAYMGNTTYTAYCAYTGGCAYYTNATHGAYACN TTYGTNTAYTTYAGYCAYMGNTTYATHACNATHCCNCCNGCNGGNTGGGTNMGNGCNGCN CAYAARAAYGGNGTNCARATHYTNGGNACNYTNATHACNGARTGGGARGAYGGNTCNAAR YTNTGYCARGARYTNYTNMGNACNAARGARACNATHGAYYTNGTNGCNACNAAYYTNGCN GAYATHGCNGTNGTNTTYGGNTTYGAYGGNTGGYTNATHAAYATHGARAAYGTNATHCAY TGYCAYMGNMGNYTNGAYGCNGCNAARGTNYTNTGGTAYGAYAGYGTNACNCAYGCNGGN TCNYTNGAYTGGCARAAYGARYTNAAYGAYAARAAYGARYTNTTYTTYTCNGTNTGYGAY GGNATHTTYYTNAAYTAYGCNATHACNGARGARAARYTNTCNAGYTCNAARCARAARGCN GARACNACNAAYMGNTGYTTYGAYGTNTAYGTNGGNGTNGAYGTNTTYGGNMGNGCNACN CCNGGNGGNGGNGGNTTYAAYTGYAAYCARGTNYTNGARGTNATHTCNAARGTNGGNYTN TCNTGYGCNATHTTYGCNCARGGNTGGGTNTAYGARAAYCAYGGNGCNGARCAYTTYGAY AAYAAYGARYTNAARTTYTGGAARYTNYTNAARGAYTTYYTNCCNMGNMGNACNCAYACN GTNCCNYTNAARACNTCNTTYTGYCARGGNTTYGGNCARAARCAYTAYYTNAAYGGNAAR GTNGTNAGYGARAARGCNTGGCAYAAYYTNTCNYTNCARCARYTNCARCCNTGYTAYAGY GAYAGY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MGNCARGAYGARGAY AGYMGNAARATGCARGTNYTNGTNTCNAAYTTYTCNGARGARCARYTNAAYMGNTAYGAR ATGTAYMGNMGNGCNACNTTYCCNMGNCCNTCNGTNAARAARYTNATGCARAAYATHACN GGNTCNACNGTNTCNCARAAYGTNGTNATHGCNATGTCNGGNATHGCNAARGTNTTYGTN GGNGARGTNYTNGARACNGCNYTNGAYGTNAGYGARAARTGGGGNGAYTCNGGNCCNYTN CAYCCNAARCAYYTNMGNGARGCNGTNMGNATHYTNAAYGCNAARGGNATGATGCCNTCN ACNAARAAYAARAARTGYYTNTTY---------------------AARGTNAAYGTNCCN AGYGAYAAYAARYTNGGNGCNGTNCCNGCNGTNATGACNGGNGAYTCNACNAARYTNCAR MGNGGNYTNATHGTNYTNCARGARTGGTGGGGNATGAAYGAYCARATHGTNACNTGYGGN AARGAYYTNTGY---GGNAARGGNAAYATGGTNACNYTNGTNCCNGAYYTNTAYMGNGGN AARGTNACNAARGAYAAYGARGARGCNGGNCAYTTYATGGGNGAYYTNGAYTGGAARGGN GCNGTNGAYGAYATHCARGGNTGYGCNMGNTAYYTNAARAGYCARGGNGTNAARAARATH GCNGTNACNGGNTTYTGYATGGGNGGNGCNYTNGCNATGGCNGGNGCNGCNYTNGTNCCN GARATHGAYGCNGCNGTNCCNTTYTAYGGNATHCCNGGNGARTCNYTNTGYGAYGTNACN ACNATHAARATHCCNATGCARTGYCAYTTYGCNYTNAARGAYGCNACNGCNGGNTTYGCN TCNCCNGCNGARTGGAARCCNYTNAARGARAARYTNACNAARACNATGAARGTNYTNGAR TTYTAYGARTAYGAYGCNGGNCAYGCNTTYACNAAYAARACNGGNGARAAYTAYAAYGAR GARCAYTGYAAYYTNGCNTTYTCNMGNATGTTYGARTTYYTNAAYAARCAYYTNTCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATHYTNGARCCNATHMGNGGNGGNTCNCCNGCNGAY AARAGYCARCCNCCNGTNGCNCCNACNCCNACNYTNYTNGAYACNAGYAARCCNGARGAR GCN------AARAARTCNYTNGAYATHCCNCCNGTNGAYTTYGAYTGGGGNTCNAGYGGN YTNACNAAYCCNYTNAARGTNTTYAARAAYGAYAGYTTYAAYAAYGGNYTNTCNTCNATH GARCCNTTYTCNGAYGTNYTNAARAAYATHGARCCNACNAARGAR---YTNAGYAAYGAR GCNAARAGYATHYTNTCNAARATHCCNAAYYTNAAYTTYATGMGNTCNAAYGTNYTNATG TTYCCNATHAAR------------------------------------------------ ------------AAYGTNTGYCAYYTNATHGCNGARAGYTTYTGYCARGAYAARGCNATH AARTCNGAYYTNYTNATHTCNTCNTGGTCNATHGARGARTGGTGGGAYGTNMGNGCNGCN YTNYTNGARYTNATGAARAARGTNGTNCAYCARGAYTGGACNMGNGARCARATHCAYGAR GARYTNGAYTCNGTNGAYGAYACNTTYAARACNACNATHTCNGARGCNATHTCNGTNCAY CAYTAYTCNYTNAARAARAARYTNYTNCARAAYACNGCNTCNATHTCNCAYGCNGTNYTN YTNGAYTTYGAYTGGAARYTNCARYTNGCNYTNTCNAGYGAYAARATGTCNAGYYTNCAY CARCCNTTYGTNACNYTNGAYYTNGAYATHMGNCAYGCNAAYGGNGAYMGNAARGARGTN GCNYTNGARATGGAYAARGARGARYTNGCNAARYTNATHTCNTCNYTNGARAGYTGYAGY AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AAYTTYTCNGARGTNYTNGGNAARYTNAGYCARGAY GCNAARATGGTNATHYTNCARTAYTCNCARGAYTTYAAYGCNAGYGARGTNTAYGARCAR CARAGYATHCARGCNGTNACNGARYTNGCNGCNCAYGCNACNGTNYTNGARCAR------ ------------------------------------------------------------ ------------GGNCAYGGNGGNCAYCAYGAYGGNAARCCNYTNGARTTYTCNTCNGAR ATHCAYAAYAARGAYCAYATHATHGARCAYYTNCARMGNCARATHTCNACNAARCCNAAR GAYCARATGACNGAYGARGARYTNGARTTYCAYTAYTTYAARYTNCAYGAYTAYGAYGAY AAYAAYAARYTNGAYGGNGTNGARATHGGNAARGCNYTNACNCAYTTYCAYGAYGARGAY ACNAAYTCNACNTCNGCN---------------------------GTNCCNGARGTNACN GARGARGARYTNGCNGARGAYGTNGAYGARGTNYTNGARGAYAARGAYAARAAYAARGAY GGNTAYYTNGAYTAYGTNGAR--------------------------------------- ------------------------------ATGGGNMGNGGNMGNTCNAGYGAYTCNGAY AGYGAYTAYTCNMGNTCNAARAARAARAARGARAARMGNMGNMGNTCNMGNAGYAARTCN TAYAGYTCNAGYGAYTCNAGYMGNCAYYTNAGYTCNAARAGYAARAARACNAARAARAGY MGNAARCAYTCNACNMGNCCNCCNTCNGTNAGYCCNGAYMGNCAYMGNGGNTCNAARGAR MGNTCNMGNMGNTCNMGNTCNMGNTCNATGGARCARMGNACNTCNMGNMGNTCNMGNTCN AARTCNMGNTCNCCNTCNTCNMGNGAYMGNMGNMGNTCNMGNTCNGGNTCNCARMGNMGN TCNMGNTCNMGNTCNCCNTCNMGNAGYTAYAAYAAYMGNAGYAAYAGYMGNMGNTCNMGN TCNGGNTCNMGNAGYMGNMGNTCNMGNTCNAGYTCNMGNGGNCAYGGNGGNAGYAGYMGN ATGAARAGYGAYMGNMGNMGNTCNMGNTCNAARTCNAGYTCNMGNGGNACNACNGAYMGN TCNMGNCAYGTNAGYCCNGARMGNTCNAARGTNGARCARGGNCARGGNATGGCNTCNTCN TCNGARAARGCNGARATHMGNATGMGNAARGCNYTNCARGCNGCNGCNGCNGCNGAYGAR AARYTNAARACNYTNMGNGAYCARGCNYTNTCNYTNTCNMGNTCNTCNCCNTCNATHGAY AGYATGTCNGARYTNTCNYTNGCNATGACNGCNTCNMGNGAYTTYGTNGAYTCNGTNGCN GCNATHGAYGCNGGNMGNTTYGTNCARTCNTCNTTYAARTCNGGNGGNATHGTNGTNAAR GARGARYTNCCNGAYCCN---YTNATGTCNAGYCAYGAYGAYGCNATHTTYGGNTCNYTN TCNTCNGTNGGNTTYACNATHAARCCNGAYGTNGAYAGYAARCCNGTNGCNATGGAYGCN GAYTCNATHATGCAYCCNTCNYTNTAYTGYAAYGTNGARGAYAARATGGARMGNTGGATH GARMGNYTNTCNCAYYTNMGNMGNMGNAARYTNGARGGNGARGCNATGATGGAYGTNGTN GTNGTNGGNAGYTGYATGACNGAYYTNATHAGYTAYGCNCCNCAYYTNCCNAARGARGGN GARACNYTNACNGGNTAYAARTTYTCNGTNGGNTTYGGNGGNAARGGNGCNAAYCARTGY ATHACNGCNGTNAAYYTNGGNGCNCARGTNGCNATGGTNGGNAARYTNGGNGAYGAYACN TTYGGNAARGAYTAYCARGTNAAYATGAARACNAAYAAYGTNAAYTGYGAYCAYYTNAAY ATHGTNCCNGGNGTNTCNAAYGGNGTNGCNTCNATHCARGTNGCNGAYAAYGGNGCNAAY TGYATHATHATHGTNCCNGGNGCNAAYAGYCAYYTNACNGTNGARGAYGTNCAYAAYGCN GARGAYGTNATHAARAAYTGYMGNGTNYTNATHTGYCARAAYGARATHCCNCARGARATH TCNYTNTCNGCNGTNAARATHGCNAARAARCAYAAYGTNAARGTNATHTAYAAYCCNGCN CCNGCNTCNTCNAGYYTNYTNCCNGARYTNTTYTCNYTNCCNGAYTAYTTYTGYCCNAAY GARACNGARGCNGARATHYTNATHGGNMGNCCNATHAARACNGTNGARGAYGCNTTYGAR GCNTGYAARATHYTNCARAAYACNAARGGNTGYCARTCNGTNGTNATHACNYTNGGNGAR AARGGNGCNGTNYTNAARGAYACNTCNTCNAAYGARGCNGTNCAYGTNTCNACNTCNTCN GTNAARGCNGTNGAYACNACNATGTCNTTYCCNGGNMGNACNCCNATGGCNATGCCNGGN GCNATGCCNGGNATGCCNCCNMGNATGATGACNACNCCNGGNTAYGCNTTYACNTCNATG GGNATGACNMGNATGAAYCCNATGATGCCNATGCARATGGGNATGATGACNCCNATGATG CARCCNATGATGCARCCNCARCARATGCARTCNCARCAR---CARCARCAYATGAARCAR AAYCCNAARTTYGTNCCNCARGARATHCCNAARACNGAYCCNAARGGNGARAARCCNCCN GTNACNACNGTNTTYGTNGGNAAYATHAGYGARMGNGCNCCNGAYATGATGATHAARCAR ATGYTNCARMGNTGYGGNAAYGTNYTNAGYTGGAARMGNGTNCARGGNGCNTCNGGNAAR YTNCARGCNTTYGGNTTYTGYGARTAYGARGAYCCNGARGCNACNYTNMGNTGYATHMGN YTNYTNAAYGAYTGGCCNATHTCNAAYAARAGYYTNGTNGTNAARGTNGAYGCNAARACN AARACNYTNYTNGAYGAYTAYMGNAARAARAARCARGGNGAYGAR---GAYGGNATHAAR AARGARCCNGARACNGGNGARAARCARGARAARGGNGARGARGARAAYGGNGAYAAYAAR AARGARGARGAYGGNAARGARGARTCNGARGARAARGAYGGN---CARYTNGAYGARAAY ACNCARMGNGARGAYMGNYTNGCNCARGCNGGNYTNGARGCNATHATGAARGARTAYGCN TTYGARYTNGCNAARGARCCNGCNAARTCNAGYGAYGGNGGNGAYCARGAYAARGARAAR CARATGCCNAARAARGARAARGARGTNTAYATGCAYGCNAARGAYACNGGNTTYGAYGAY ATGGARATGGARGAYGAYAARMGNGARATHATHAAYMGNGARATHAAYAARTTYMGNGAY MGNCAYAARGAYGAYGAYGARGARAARGARAARAAY---MGNGARAARGARMGNAGYYTN GCNMGNGARMGNGAYMGNMGNCARGARGARAARMGNCAYMGNGARMGNYTNGARAARYTN MGNGARCAR------------------------MGNGARMGNGARMGNGARMGNCCNCCN ACNMGNGTNTCNMGNTCNAARTCNMGNTCNGTNTCNCCNGTNCCNTCNMGNTCNMGNMGN MGNTCNMGNTCN------------MGNGARMGNACNAGYMGNGAYMGNTCNMGNGARMGN MGNAARGARMGNGARATHGARGARGARGARGARATHTAYGARMGNMGNAARYTNGARAAR AARYTNMGNGARAARGARGCNGCNTAYCARGARMGNYTNAARAAYTGGGARGGNMGNGAR MGNAARAARACNMGNGARTAYGARAARGARAAYGAYMGNGARGAYGARMGNAARGTNGAR GARGGNMGNGARGCNMGNMGNYTNAARGARTTYYTNGARGAYTAYGAYGAYYTNMGNGAY GAYCCNAARTTYTAYAARGGNAGYGCNYTNCARMGNMGNCARAARGARMGNGARAARGAR AARGARYTNGAYAAYMGNGAYMGNCARMGNGARAARGARGARTTYGARGARATHAARMGN AARYTNTTYGAYGARGGNCAYCCNGAYGCNGARACNGARGTNGCNMGNATGGARMGNGAR MGNGARGARCAYYTNCARCCNMGNYTNCAYYTNCARGARYTNAARCARCCNCCNCARCCN GTNGTNAAYGARGARTCNGAYTCNGAYAAYGARCCNCCNCCNTCNAGYAARGCNGARCCN MGN------CARCCNCCNTCNCCNAARCARTCNGAYCAYYTNCCNCARTCNMGNAAYGGN CCNCARCARCARCAYCARYTNATHCCNGARCARCARCARCARCARCARCARCARCARMGN CCNTCNCCNTCNYTNTCNACNTCNCCNATHTCNACNGAYTCNMGNGTNAGYAGYGCNCCN GGNYTNTGYATGGAYGARTCNTCNCARTCNTCNTTYCCNCCNGCNGCNCCNCCNYTNATG TCNTCNTCNTCNTAYGGNGARCCNMGNYTNGGNAAYAARCAYTCNACNACNTCNACNTCN TTYAAYAAYYTNGCNCCNGGNATGAGYCCNGAYTCNTCNAGYYTNCCNGGNGTNGTNACN ATHTCNGAYGGNAARMGNAARAARYTNACNGTNGGNGAYGTNTTYAAYCARGAYGAYGAY GAYAGYAAYGARCCNAARAARMGNAARYTNATHCCNYTNGAYTAYGAYGARGAYAARACN ACNCCNACNGARAARAARGGNGCNACNGCNGARGARAARMGNCARAARATHAARCARYTN ATHGARAAYATHCCNACNGCNAARGAYGARYTNTAYGCNTAYACNGTNGAYTGGGAYATH GTNGAYCARGCNYTNATGGAYAARMGNATHAARCCNTGGGTNACNAARAARATHGTNGAR TAYATHGGNGARGARGARCCNACNYTNACNGARTTYATHTGYCARAARGTNATHGCNMGN AGYACNCCNCARAGYATHCARAAYGAYGTNGCNATGATHYTNGAYGARGARGCNGARGTN TTYGTNGTNAARATGTGGMGNYTNYTNGTNTAYGARACNGARGCNAARAARYTNGGNYTN GTNAARYTNGTNACNGARGARTAYAAYAARCAR---GCNGCNYTNTGGCCNCARGARGGN AARCAYATHYTNGCNCAYTAYGAYGAYGARACNGTNGTNGTNTAYCARGCNTAYAAYCCN MGNATHGCNAGYTAYGCNGTNAARTAYCARAARTTYGGNGGNCCNGAYTTYAARTAYGAR MGNATGTCNTGGATHAARCCNAAYTTYATGTGGATGATGTAYMGNTGYGGNTGGGCNCAR AARAARGAYCARGARMGNGTNYTNGCNGTNTGGYTNACNMGNCARGGNTTYGARAAYATH YTNGCNGTNGCN------------AARACNGGNAARGARAGYGAYTCNGGNAARACNGAY GARGTNMGNATHCARTGGGAYCCNGAYCAYAAYCCNCAYGGNAAY---AGYYTNACNMGN MGNGCNATHCARYTNGGNYTNMGNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GGNMGNTCNCCNGTNGARGCNMGNGGNGGNCARYTNGARATHGCNGGNGTNGTNGTNGGN CARTGGGGNCCNAAYATGTCNGGNMGNMGNGGNMGNGGNGGNCARYTNTCNCCNCARATH ATGTCNGTNGGNCARMGNGGNATGTAYAAYGGNMGNGGNTTYATGCCNACNMGNGGNGCN TAYCCNGGNAAYTAYGGNMGNGGNMGNGGNTCNCCNMGNCCNGTNMGNATHGTNGCNMGN CCNGGN------------------ATHCCNYTNYTNGARGAYATGACNGAYATHYTNCAR AARGCNGARYTNYTNMGNGARCARAARTTYGGNTCNAGYGGNCARACNCARAARACNTCN AARAAYGARGAYGCNAARAARMGNGCNAARGTNACNAARAARAAYGTNGGNAAYGCNACN GTNGTNTCNACNAAR--------------------------------------------- ---------------CARACNCCNGAYAGYGARAGYAARTCNGARAARAARGAYGARGTN CARAGYGTNAARCCNGCNAGYTCNAGYAGYCARGGNATGTTYGGNGGNATGAARAARGGN TTYYTNTTYGGNGGNTCNAGYAARCARCCNAARTCNTCNTCNAAYACNTAYGGNAARCAR GCNCARGAYCARACNACNAAYAARGARAARAARTCNAAYCCN------------------ ------AARACNACNCCNAARGARGAYYTNCCNTTYATHACNCCNTCNGGNAARACNGAR TCNAGYYTNACNTTYAAYGARGTNCARCARGCNATGTCNGARGCNAARGGNYTNYTNGAY AAYCARGARTGGATHACNGAYGAYTTYYTNAGYAARATHGARAARAAYGARAAYYTNYTN AARMGNTTYAGYGAYCCNCARTTYATGTCNGCNYTNCARGARTTYCARACNAAYCCNCAR GCNGCNATGGARAARTAYAARGGNAAYACNGARGTNGARAARTTYYTNATGGARTTYTGY GGNYTNYTNGGNGAYCAYTTYACNAARYTNGGNAGYAGYAAYGAYCARTCN--------- ------------------------------------------CARCCNACNGARAAYAAR AGYTCNAARCCN---CARCCNGTNGCNAARCARAARGCNCARAAYGAR------------ ---------------------------------------------CARYTNCARTCNGCN ACNCCNAARATHGTNGARATHGGNAGYGGNGAYGAYYTNGGNGAYGARCCNYTNAARGCN TCNAARTCNGARYTNAGYAAYTGYAARGCNAAYTCNAARCCNGCNGCNAARAAYATHCAR ATHCAYGAYCCNCARAARGGNGCNGAYATHCARGARYTNCCNTTYAARCCNGARACNCAR ACNGAYGAYGAYGCNGTNMGNGARGTNYTNAAYGAYCCNAARGTNATGGARACNYTNATG GAYCCNAARATHATGGCNYTNATHAARACNYTNMGNGARGAYCCNGARAARGGNCARMGN ATHATHGAYAARGCNGAYGGNGAYYTNAARGARAARGTNMGNTTYYTNGTNGCNMGNGGN YTNYTNCARTTYCAR---------------------------AAYGTNTCNTCNYTNYTN YTNCARGAYCAYGARAAYGARACNYTNTTYCARACNYTNGGNMGNYTNTGYGTNACNYTN GCNACNGGNGTNGTNCARYTNTAYYTNGCNGAYCARAGYGAYMGNGCNMGNTGGAAYAAR MGNTGYTGYGGNGTNGCNTGYTTYGTNAARGAYAAYTCNAARMGNTCNTTYTTYATHAAR GTNTTYGAYATHAARAARCARCARATGYTNTGGGARCARGARYTNTAYAAYCARTTYGTN TAYAARACNCCNMGNGARTAYTTYCAYACNTTYGARGCNCAYAAYTGYCARGCNGGNYTN AAYTTYGCNGAYGARGAYGARGCNATHAARTTYAARAARGCNGTNGARGGNAARYTNAAY GARMGNMGNCARAARAARATGGARMGNMGNCARAARTCNGTNTCNAGYAARCAYGGNGTN GAYCARGGNCCNGGNGCNAAYCCN------------CCNCARMGNATGGGNGGNACNAAY AAYGCNGCNCCNACNCAR------ACNGTNGAYGTNAAYMGNATGAAYAAY------AAY AAYCAYAARAARGARAARGAYAARAARAARGARAARGAYAARAARAARAARYTNACNAAR GARGAYATHGGNTCNCCNTCNAAYTTYGTNCAYATHAGYCAYGTNGGNTGGGAYCCNGAY AARGGNTTYGAYATGAAYAAYYTNGARCCNGAYATGCARACNYTNTTYCARTCNGTNGGN ATHAARCCNGARGAYAARGTNGAYAARGAYACNGTNGAYTTYATHTAYGAYTTYGTNGAR AARMGNGGNGGNATGGARGCNTTYAGYAARGARYTNMGNAGYAAY---------ACNAGY MGNCCNCCNGCNCCNCCNGCNAGYATGGGNMGNMGNGCNCARCCNCCNCCNCCNCCNGCN MGNTCNCCNGGNGGNCCNCCNCCNCARMGNAGYGGNGGNGCNCCNCCNCCNCCNCCNCCN TCNMGNGGNCCNCCNCCNCCNACNATGMGNGGNGCNGTNCCNCCNCCNCCNCCNTCNMGN GCNATGCCNGCNCCNCCNMGNGCNCCN------------------------------GCN GCNCCNYTNCCNCCN------------CCNCCNMGNCCNCCNTCNTCNGTNCCNCCNCCN CCNCCNCCNCCNATGATGGGNGGNGGNGGNTCNGCNGGNATHGGNGTNCCNCCNGCNCCN CCNCCNCCNCCNCCNATGGCNTCNYTNTTYGARGARCAYMGNYTNYTNACNAARAARGTN TTYGAYGARATHTAYATHCCNGARAARGAYMGNGAYAAYTAYAAYACNGTNCARGCNAAY GARGCNYTNGARGGNAARGTNGTNTGYYTNTTYTTYTCNGCNTCNTGGTGYACNCCNTGY CARCAYTTYGTNCCNACNYTNAARGARGTNTAYTCNGARYTNGTNCAYMGNAAYAGYCCN YTNGARATHGTNTTYYTNAGYTTYGAYAARACNGARGAYGARATGATGAAYTAYTAYCAR GARAARCAYGGNGAYTGGYTNACNGTNAARTTYGGNGAYCCNYTNAARCARGARYTNGTN GARMGNTAYTCNATHAGYGTNATHCCNAARYTNATHGTNGTNCARCCNGAYGGNGARGTN ATHAGYAGYAARGGNMGNAARGAYGTNCARGAYMGNGGNGTNGTNTGYATGMGNGCNTGG CARGCNGGNTTYGAYAARTAYATGCAYCAYAARGARCARGARMGNTCNTCNGTNCARYTN TTYMGNATHCARMGNGTNGARATHYTNACNYTNTTYCARYTNYTNAAYATGGTNYTNTGG ATHGTNGAYGTNCAYTAYAARTTYYTNCCNGTNTCNATHYTNCCNGCNYTNATGATHTTY ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNTCNGGNATGMGNAARCCNTAYMGNGARAAR CARGAYGTNTTYGAYGTNAARCAYYTNGCNTCNAARGARCCNTTYGARCARTTYAGYGCN TGGTTYGARGARGCNAARTCNATGCCNGGNATHTTYGARGCNAAYGCNATGGCNYTNGCN ACNGCNACNMGNGARGGNAARCCNTCNGTNMGNATGGTNYTNATGAARGGNYTNAGYAAR GAYGGNATHGAYTTYTAYACNAAYTAYCAYAGYMGNAARGCNCARAAYYTNATGGARAAY CCNATGGCNAGYYTNATGTTYTAYTGGGARTCNYTNAAYAARTCNGTNMGNATHGARGGN AARGTNGARAARYTNTCNCARGARCARTCNGARAARTAYTTYCAYTCNMGNCCNMGNTCN AGYCARATHGGNGCNTGYGTNAGYGARMGN---CARAGYTCNGCNATHCCNTCNMGNGAY GTNYTNGAYAARMGNAARGARAAYYTNGARTCNCAYTAYAGYGAYGARAGYGTNGTNATH CCNAARCCNGAYTAYTGGGGNGGNTTYMGNYTNGTNCCNGAYAGYTAYGARTTYTGGCAR GGNCARTCNAAYMGNATHCAYGAYMGNATHGCNTTYMGNAARCCNACNCCNGGNGARGCN ATHGAYCCNGCNGTNACNTTYCARGGNMGNGARGGNTGGGTNTTYGARMGNYTNCARCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNTAYGCNAARTTYGGNAGYMGNATGATHTGGGGNAARMGNGAYACN GTNGTNAARTCNTGGCAYAAYYTNMGNGGNAARCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GARAARCAYMGNCARCARCARTTYAARGCN CAYGGNGTNAAYCAYAARATHTTYAARGARCCNCARYTNGGNGTNMGNAARGTNCCNGCN AARCCNCCNACNACNATHCARGARTTYAAYYTNCAY------------ATHAGYAGYTCN CAYGTNMGNTCNAARGAYTCNACNGGNGARAARACNGGNTTYCAYGCNAAYCCNATHAAY CAYAARATHYTNGAYGGNCCNACNGGNGTNAARCCNGCNGAYAARMGNCCNYTNACNGTN GCNCARTCNCCNGCNTTYTCNYTNAARAAYMGNYTNMGNCCNCCNGARGTNGTNCCNCCN ACNGARCCNCCNAARGTNTTYTCNAAR------CCNGTNCCNCAYATGGGNGTNCCNTTY MGNCCNCARYTNGARCAYAARTAYACNGTNACNAARCCNTTYGCNGTNGARCARCAYAGY AARGARATGYTNAARAARAARGARYTNAARATHCARCARGTNYTNGARGARGARAARAAR GCNMGNGARTTYCAYGCNAGYYTNYTNCCNAGYAAYAGYCCNGAYCARYTNCCNGCNAAR MGNACNMGNCCNGTNACNGCNGTNGARCCNTTYAGYYTNGCNATHGAYGARMGNGGNAAR AARTAYCARGARGARTGGAARTCNAARCARATHGARGARGARGARGAYCARGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GTNGARCAYGGNGGNAARGAYGAYCCNCAYGGNGGNGTNCCNATGGGN ATHCCNAAYCAYTTYTGYGAYGAYGGNCARAAYTTYACNTCNATHGAYTGGGAYCCNTCN TCNACNGAYGARTAYACNTGYYTNGARGAY------MGNGAYYTNGAYATHYTNMGNCAY ---------AGYTAYGARTCNTGYGARGARATGGCNAARMGNCCNGTNCAYGTNTGYTTY CCNGARCARATHTCNTAYGAYGARGAYYTNCCNACNAGYGGNMGNCAYMGNCCNYTNTGG CCNCARTAYGGNGARTAYMGNTAYYTNCCNCCNCARMGNTGGYTNCAYTCNYTNGARCAY GGNGCNATHGTNTTYYTNTAYAAYCCNTGYGCNAAYGARGAYCARATHMGNAARYTNAAR GCNYTNGCNMGNGGNTGYATGMGNMGNCAYATHATHTCNCCNTCNAARMGNATHCCNAAR CCNAAYATGTTYGCNGTNYTNGCNTGGMGNTGYAARYTNGTNATGACNCAYGTNGAYGTN CCNAARACNGTNGCNTTYGTNMGNGARCAYGCNYTNCAYTCNCCNGARMGNTCNGTNTTY ACNGAYGGNCARTAYAGYGTNGCNYTNACNCAYCAYGCNAARATGGTNACNACNCARGAY GARATHAARYTNTGYCCNGARATGTCNYTNATG--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------MGNATH AARTGYTCNAARGAYAARATHTTYATHGGNGAYMGNCAYTAYCARTCNGCNACNGAYGCN YTNYTNGCNTAYYTNMGNCARTTYGARACNGTNTCNGCNGTNGTNGGNGGNAAYGGNGCN TCNTCNMGNGGNGGNACNCCNGCNGGNACNAAYGGNGCNAGYGAYGTNGAYYTNAAYGGN ATHGGNGTNGAYAAYAARAARGAYGARGTNCARCARYTNYTNACNTCNAARGTNTCNCCN GARYTNAARGARGARGTNACNGAYACNYTNMGNGARATHAARYTNAARAAYYTNYTNAAR AARGCNGTNTCNAARTCNCARAARCCNGGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------YTNGCNTCNAARAAR TGGTCNAARCCNGTNGTNATGGGNTCNCCNCCNCCNGCNMGNTCNGCNGCNTCNYTNGTN GCNGTNGGNACNAARYTNTAYYTNTTYGGNGGNYTNAGYCAYATHTGYGGNTGGTTYGAY GAYATHCAYACNTTYGAYACNGTNACNAGYACNTGGTCNATHYTNGARACNGARGGNACN AARCCNMGNGCNMGNGAYAARYTNCARGCNGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CARGAYCCNGCNTCNTTYGGNCARGARTTYGTNGAYATGGTNMGNCCNGCNYTNGTN ACNMGNTAYMGNYTNYTNCCNTAYATHTAYACNTCNGTNTAYACNGCNCAYACNGARGGN MGNYTNGTNATGCARCCNYTNTTYTAYCARTTYCCNCAYGAYAARAARACNYTNGCNATH GAYMGNCARTTYATGYTNGGNGAYAGYYTNYTNGTNTCNCCNGTNYTNGAYCARGGNGCN ACNAGYGTNCARGCNTAYTTYCCNGARGGNMGNTGGTTYGAYTAYTTYACNGGNGARGAR ATHAAYAARGGNGGNAARMGNGTNGAYYTNGCNACNCCNYTNGAYAARTTYAAYYTNCAY ATHMGNGGNGGNCAYGTNATHCCNTGGCARGARCCNGGNGCNAAYACNGARGARAGYMGN AARGGNCCNATGGGNYTNATHGTNGCNYTNGAYCARACNGGNMGNGCNCARGGNCARYTN TTYTGGGAYAAYGGNTCNTCNAARYTNACN------ACNTAYAAYATHGTNACNTTYACN ATGGARAARGGNACNYTNACNATHACNGCNCARACNAAYAARTTYGCNGAYACNYTNAAR TTYGARACNGTNGARATHTAYGGNYTNCCNMGNATGCCNTCNAGYGTNAARGTNAAYATG CAYYTNCCNGCNGAYYTNAAYGGNTTYACNCCNTTYCARGARTTYACNATGTCNGARYTN GGNGTNGCNCCNGGNGAYMGNCCNYTNACNTGYGTNYTNAAYGAYCAYCCNGGNGARYTN GTNAARACNGGNAGYCCNAAYTTYYTNTGYTCNGTNYTNCCNTCNCAYTGGMGNTCNAAY AARACNYTNCCNGTNCCNTTYAARGTNGTNTCNYTNGGNGAYATHMGNGAYGGNACNAAR GTNATHATHACNGCNGGNAAYGAYGARAAYTTYTGYTCNGARYTNMGNAAYAAYACNGCN ACNATGAARAAYCARGTNGCNAARTTYAAYGAYYTNMGNTTYGTNGGNMGNAGYGGNMGN GGNAARAGYTTYACNYTNACNATHACNGTNTTYACNAAYCCNCCNCARGTNGCNYTNTAY CARAARGCNATHAAR--------------------------------------------- ------------------------------------------------------------ ---------ATGYTNACNATHACNGAYTTYATHAAYATHYTNAARCARTAYTAYAARACN TCNGGNACNAARATHGARGARYTNGARGARCAYAARATHGCNACNTGGMGNGARGTNYTN AARGGNMGNCARAARCCNTTYGTNTCNATHTAYCCNGAYAARAGYYTNTTYGARGCNGTN AARACNYTNGTNGAYCAYCARGTNCAYMGNYTNCCNGTNGTNGAYGARATHACNGGNAAY GCNYTNTAYATHYTNACNCAYAARMGNATHYTNMGNTTYATGCAYYTNTTYTTYAARGAY YTNCCNCAYCCNGCNTAYATGAARAARTCNATHAARGARYTNGGNATHGGNACNTAYGAR AAYGTNATHACNGCNAGYCCNGAYATGACNYTNATHAARGTNYTNAAYYTNTTYTCNAAY AAYMGNATHTCNGCNYTNCCNGTNGTNGAYGAYAAYTCNGGNAARATHATHGGNATHTAY GCNAARTTYGAYGTNATHAAYYTNGCNGCNGARAARACNTAYAAYAAYYTNGARATHACN YTNAARGARGCNYTNGAYMGNMGNTTYGAR---AAYCAYCARGCNGGNGARAARGTNGTN TCNTGYCARTCNTCNGAYTCNYTNGARGAYGTNGTNAAYAARATHGTNAARGCNGARGTN CAYMGNYTNGTNGTNGTNGAYGARTCNGGNAARGTNGAYGGNATHATHTCNYTNTCNGAY GTNYTNAAYTAYACNGTNYTNMGNCCNATHGARGARGTNTCNGARGARGAYTTYGTNGTN YTNGGNACNCCNGTNCCNGARYTNGAYGARAGYGARGCNACNAARAARCCNACNACNYTN CARGAYYTNACNGCNAARGAYAARGARGGNMGNMGNMGNTTYCAYGGNGCNTTYACNGGN GGNTAYTCNGCNGGNTAYTTYAAYACNGTNGGNTCNAARGARGGNTTYACNCCNTCNGTN TTYGTNTCNTCNMGNAGYCARAARCARGARGAYGCNCARACNYTNMGNCCNGARGAYTTY ATGGAYGAYGARGAYYTNGARGARCAYGGNATHGCNCCNMGNAARTTYGCNACNGCNMGN AAYTAYTCNTCNGARGARMGNAARMGNAARYTNGARAAYGTNGCNGCNCARYTNGCNCAR TCNTCNACNYTNGAYYTNGGNGGNGCNYTNTCNGAYYTNATHATHCCNGAYTAYYTNCCN ATHGGNATHAARYTNYTNMGNAARATGGGNTGGMGNGARGGNCARGGNYTNGGNCCNMGN GTNAARAARAARAARCARAARACNAARAARAARGARTCNAARAARGGNAARAARGTNTAY GGNTGYGCNMGNCCNCCNTCNAAYTCNGAYAGYGAYGAYTCNGAYTCNTTYATHCCNTCN AAYYTNAGYGAYYTNACNTTYGCNCCNTCNGAYGTNACNCCNGTNTGYYTNAGYGCNAAR GAYGAYGTNAARGGNYTNGGNTAYMGNGGNYTNGAYCCNTCNYTNGCNYTNCCNGGNTCN CAYGTNAAYYTNTTYGCNAAYCCNGTNAARGGNAARMGNGCNGGNAARGGNATHMGNGGN CAYGCNTTYGGNGTNGGNGCNYTNGARGAYGARGAYGAYGAYATHTAYGGNCARGAYAGY YTNTCNAAYTAYGAYYTNACNATGMGNGGNGAYGAYAARGGNCAYGAYGGNAAYTTYGGN TGGACNGCNCCNCARGCNCAYGGNAARCARAARGTNCCNGTNTCNTAYGTNGGNAARYTN YTNGARGGNTTYTGYYTNTCNTCNAARCCNYTNCARCCNMGNAARAAYTTYCCNCCNCCN AARYTNCCNCCNAAYTTYAARCCNCAYCAYTGGTCNMGNMGNMGNAAR------AARGAR GARGAYGAYGGNAGYGGNCARCARTAYAAYYTNAGYGTNGTNGAYMGNGGNYTNATGYTN GGNGARACNCCNATHATGAAYTCNGTNTTYGAYYTNGTNGGNTCNAARGAYAARTCNMGN ATGGARTGYGCNAARGARGCNATHCARATGACNAARTCNYTNGAYACNTCNTCNGGNACN GCNGCNGTNGCNAGYGTNAAYGARAARGGNGGNAARGAYTCNCARACNTCNAGYGTNCCN GGNCCNGARCARAARAAYCCN------------------CCNTCNAARTTYYTNTCNMGN TTYACNGARGCNAGY---ACNGAYACNAGYAAYGGNAAYACNAGYACNTCN--------- ------------YTNTTYAARGGNTCNYTNAGYYTNCARCCNTTYMGNAARGAYCCNGCN AARCARGCNMGNTTYGAYCARTAYYTNGCNTGYATHCARCARAARYTNCCNGAYCCNTAY AGYCARGTNTCNAGYAGYMGNATGACNGARTGGGARAARGCNMGNGARMGNGAYGARTTY AGYMGNTCNGCNMGNYTNTAYMGNCCNATGTCNGCNATGATGTCNGCNMGNTTYGTNGTN GGNGCNATGYTNGAYGAYAARAAYCARGAYTCNAARACNGARGCNGGNGGNGARGCNACN GAYGARGTNAARGCNTCNGARATGMGNATGTTYGGNAARYTNACNMGNGARGARTTYGAR TGGCAYCCNGAYAARYTNGTNTGYAARMGNTTYAAYGTNCCNAAYCCNTAYCCNGGNTCN GAYATHGTNGGNYTNCCNACNGTNAARMGNGAYAARTTYTCNATHTTYAAYTTYYTNAGY TAYGGNGAYTAYMGNCCNAARGAR------------CCNGAYACNGGNTCNGARMGNTCN GCNGARAARGARGTNCCNGGNAARTCNGARTGGGGNACNCAYAARCCNGARAARAARAAR GCNATGYTNTCNTCNATHTTYAARGTNYTNGAYGAYCCNGAYTTYCAYATGCCN------ ------CCNACNGAYATHAARTCNGARGARCCNTCNGARCARAARATHGARGGNAARGAY GTNAGYCARGARGARGARAARCARCARGARGARGARGARGCNGAYGTNGAYYTNTTYMGN GCNATHTTYAARAAYTCNGAYTCNGARGAYTCNGARGAYGAYMGNAARGAYGAYGAYGAR TCNATGAGYGAY------GAYGAYAARGAYGARAARGAYAAYGAYGAYAAYAARGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TCNYTNACNGTNTGYGTNCCNTCNGARATHGCNCARGTNGTN MGNAARGTNYTNGARGARAAYAARYTNTGGGAYTGYAGYMGNAARYTNCARMGNCAYGGN GARTCNGTNGCNATHCCNATHYTNAAYTAYAAYGGNTCNCARATGTCNACNYTNYTNCAR GAYTAYCCNGGNGCNGTNATHAARGARYTNTCNYTNCCNGTNTCNGCNAARAGYGTNMGN YTNATHACNAAYAARYTNGCNYTNYTNTCNGARATHCCNMGNAARTGGGARMGNCAYGGN GAYYTNGTNYTNYTNCCNTCNTCNGCNTTYACNTCNTCNGAYTGGGGNMGNYTNGGNGAR GARYTNTGGCARACNGTNGCNTGYGTNYTNTCNTGYCAYMGNYTNGCNMGNCAYTCNACN GTNGCNAAYAAYGGNTTYMGNACNCCNCARGTNTCNYTNYTNYTNGGNAARGAYGGNAAR GTNGTNCAYATHGAYAAYGGNATHAARTAYAGYTTYGAYGTNACNAARTGYATGTTYAGY TCNGGNAAYATHAGYGARAARYTNMGNGTNGCNTCNTGGGAYTGYTCNAAYGARACNGTN GTNGAYYTNTAYGCNGGNATHGGNTAYTTYACNYTNCCNTAYYTNGTNCAYGCNMGNGCN MGNCAYGTNCAYGCNTGYGARTGGAAYCCNGAYGCNGTNGARGCNYTNMGNGARTCNYTN TCNTTYAAYGGNGTNGCNGAYMGNTGYACNATHCAYCARGGNGAYAAYMGNCARYTNCAR YTNTCNTGYGTNGCNGAYMGNGTNAAYYTNGGNYTNATHCCNAGYAGYGARGARGGNTGG MGNGTNGCNACNMGNYTNYTNAARTCNACNGGNGGNGTNYTNCAYATHCAYCARAAYGTN ACN---------TAYGTNGGNCAYCAYTAYGCNGGNCCNGGNAAYCAYTTYTGYAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY TTYGAYGCNCCNTGYGCNACNYTNGCNAARAAYYTNYTNGGNCARTAYATHGTNMGNTCN GTNGGNTCNCARATHATHAARGGNCARATHGTNGARACNGARGCNTAYATHGGNCCNGAR GAYAARGCNGCNCAYAGYTAYCARGGNAARMGNACNCCNMGNAAYGARGCNATGTTYATG ACNCCNGGNACNAGYTAYGTNTAYAAYATHTAYGGNATGTAYTGYTGYYTNAAYATHTCN AGYMGNGGNGARGGNTGYGCNGTNYTNYTNMGNGCNYTNGARCCNGTNGARGGNCARGAY GTNATG---------GCNGARGGNMGNYTNAARAAR------GAYAARAARCCNTTYAAR GARAARGCNYTNACNAAYGGNCCNTCNAARYTNTGYCARGCNYTNCAYATHAAYAARAAY GAYTTYAAYAARGTNGAYYTNACNYTNTCNGAYGCNYTNTGGYTNGARAARGGNYTNGAY GTNGAYAGYGGNAAYATHGTNAGYTGYGCNMGNATHAAYATHGGNTAYGCNGAYGAYTGG AARGARAARCCNYTNMGNTTYTAYATHCARGGNAAYCCNTGYGTNAGYGTNMGNGAYAAR AARGCNGARACNAARGGNAAYTCNAARGGNAARATGGTNTGYTAYTAYACNAAYTGGGCN CARTAYMGNCCNGGNYTNGGNAARTAYACNCCNACNGAYYTNGAYGCNTCNYTNTGYTCN CAYATHCAYTAYGCNTTYGCN---AARYTNGAYTCNAGYMGNATHGCNCCNTAYGARTGG AAYGAYGARAGYACNCARTGGATGAARGGNATGTAYGARAARYTNAAYGAYYTNAARAAR ACNCAYCCNGGNYTNAARACNATGYTNTCNYTNGGNGGNTGGAAYYTNGCNTCNGGNCCN TTYACNMGNATGGTNGCNTCNCCNCARAAYMGNGCNGTNTTYATHAARAGYGTNGTNGCN TTYYTNMGNAARTGGACNTTYGAYGGNYTNGGNYTNGAYTGGGARTAYCCNGGNTCNMGN GGNAGYCCNGCNGGNGAYAARCARMGNTTYACNYTNYTNGTNCARGARACNATGGCNGCN TTYCARCARGARTCNGCNTCNACNGGNYTNCCNMGNYTNYTNYTNTCNGCNGCNGTNTCN GCNGGNAARAGYACNATHGAYACNGCNTAYCARGTNGAYAARGTNACNAGYGTNYTNGAY TAYGTNGTNGTNATGACNTAYGAYTTYTTYGGNGCNTGGAAYCCNTAYACNGGNYTNGTN AGYCCNYTNTAYGGNCCNAARAAYGCNACN---GGNATHGAYGCNATHTTYAAYGTNGAY TAYGCNGTNMGNTAYTGGGTNTCNAARGGNTGYCCNAARGAYAARATGGTNGTNGGNGTN ATHTCNTAYGGNMGNTCNTTYACNYTNACNGAYCCNTCNAAYTCNGGNYTNMGNGCNCCN GCNAAYGGNGCNGGNTCNCCNGGNCARTAYACNMGNGARGCNGGNTTYYTNTCNTAYTAY GARGTNTGYMGNATGATHAGYAARGGNGCNAARATHGTNMGNYTNGARGAYGARAARGTN CCNTAYYTNGTNYTNGGNAAYCARTGGGTNACNTTYGARGAYCCNACNAGYATHAGYGTN AARGCNGAYTAYATHACNCARGGNGGNTAYGCNGGNGCNGCNATGTGGGCNGCNCCNYTN GAYGAYTTYCAYGGNGCNGTNTGYGGNCARGGNGCNTAYCCNYTNYTNTCNACNGTNTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GGNATGTGYCARCARTGGAARGGNTGY------------------GGNGTNMGNGARACN AGYATHGTNACNTCNCCNAARAAYGGNACNCAYYTNATGYTNYTNGTNGGNTCNAGYAAR CARTGGYTNTCNYTNTTYYTNAAYAAYGARTCNGARAAYGAYGARAAYGARACNGAYATH GARATHCCNYTNYTNGAYATHACNCCNAARGGNGAYGTNGTNTAYGAYYTNGGNMGNAAY GCNACNATGGAYATHGCNTTYCCNMGNGARAAYGTNMGNCARGAYCCNGGNAGYGGNGCN TCNTAYGTNTTYGTNAARCCN------CAYGAYATGAARYTNATHACNGAYCAYGAYAGY MGNGCNGARYTNYTNAAYCCNGGNAARGARAAYAARTTYYTNGAYAARGTNGARATGACN GTNTAYATHAAYACNTCNATHATHCCNTAYTCNGGNGTNATGAAYYTNTAYTCNGGNGTN ACNMGNGARAARGGNGTNGTNAARMGNGTNGARAAYCAYAARGARATHGTNYTNMGNCCN TCNACNCARACNGARCCNTTYCCNGARGGNACNTTYCCNYTNCCNAAYAGYMGNGARAAY GAR---------AAYGGNGARATHGTNAGYCARTGYAGYTAYGGNAARGTNTGYCARAAR TAYTGYCARTTYTTYGGNAARGAYYTNACNAGYYTNGARYTNTTYAARAAYGGNAARACN ACNCCNGARCAYATHGARATHTTYGAYACNGCNAGYYTNTCNTAYCARAARGCNGGNACN TTYGARYTNYTNCCNATGGARGGNGAYTCNTTYCCNGTNACNTAYACNTGYAARGCNGGN AAYGTNGARGGNCARACNGCNGARTGGAAYGARGTNGTNGTNTTYGGNTAYGAYGTNAAR ATHYTNACNAAYGARTCNAGYTTYGARATHTTYGAYAAYGGNACNGGNAARATHGTNTGY ACNGCNMGNGGNATHCCNYTNCCNAARGTNGARCCNGARACNMGNGTNCARGARGGNCAR CCNACNCARYTNCAYTTYTTYYTNCCNCARYTNGCNGAYACNATGAGYGARGTNTCNGGN ACNGCNACNGCNMGNAGYTTYTAYCARGARCARMGNYTNGARYTNYTNTCNMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GARATHATGAARAAY TTYYTNGCNMGNTTYCCNGCNATHGAYTCNTTYACNAARAARTGYTGYTCNTAYGCNAAR GARTAYGGNTAYACNGARACNATHTGYGGNMGNMGNMGNTAYTTYCCNTAYATHAAYAGY MGNTCNCCNGCNYTNMGNGCNCARGCNCARMGNCARGCNGTNAAYTTYTGYGTNCARGGN TCNGCNGCNGAYATHTGYAARYTNGCNATGYTNGARGTNGARTCNGAYYTNAARAARCAR CCNGCNYTNAAYTAYMGNYTNYTNYTNCARATHCAYGAYGARYTNYTNTGGGARGTNGCN GARGARCARYTNYTNCARATHAARGARATHATHGARAAYGTNATGGARAGYGCNACNATH YTNTGYCAYAARTTYTGYTCNYTNCARGTNCCNYTNACNGTNTCNTTYAGYCARGGNAAR TCNTGGGCNCAYYTNATHCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGGTNGARGCNGAYGTNTCN CCNGGNGAYATHGAYCCNGAYATGCAYGCNGCNYTNCARAGYATHATGGARGARYTNATH GAYGARGTNACNYTNGGNYTNTGYTTYGARATHCAYMGNTCNTGYAARATHGGNTCNTTY TTYYTNGAYGGNGGNGAYGAYATGTCNGAYACNGARTAYGCNATHATHGARMGNCCNGGN GTNGAYGTNYTNGGNCARGTNCCNTCNAARAARAAYTAYGARTGYGTNTGYCCNAAYTGY CARMGNCAYYTNGCNGCNTCNMGNTTYGCNCCNCAYYTNGARAARTGYATGGGNATGGGN MGNAAYTCNTCNMGNATHGCNAGYMGNMGNATHGCNAAYAAYCARAARCAYGGNAGYGAY GARAGYGGNCARGAYGAYGARAAYGAYAAYGAYTGGAAYTAYGCNCCNGARTCNAARMGN YTNMGNAARYTNAARAARGAYAARATGTCNAAYTCNCCNMGNAAYMGNMGNYTNGCNAAR YTNMGNACNAAYAAYTTYMGNAARYTNMGNAAYGGNGGNGAYCAYCAYACNACNACNGCN GCNGCNACNGTNACNCCNGCNTCNGCNGCNGTNACNACNGCNGGNGTNACNGTNTCNTCN TCNGCNGAYYTNGGNGGNGCNGAYTAYCAYGAYATHCARGAYCAYATHCCNAAYTAYGAR ACNATGAGYYTNGARGARMGNAARGCNYTNYTNYTNACNAARTGYGGNGTNATHTCNGAR ATHACNAARAARATGTGYACNMGNTCNACNAARTGYGCNCARCAYACNGAYGARCARMGN MGNCAYGTNMGNCARCAYYTNYTNMGNCARAGYMGNCCNCAYGAYYTNGARGAYATHCAY ATHGAYATHGAYACNTAYGAYGAYGCNGARTCNCARTCNYTNMGNGARTCNYTNCARTGG GARGCNTCNTCNAAYTCNTCN---------------------AAYAAYAGYACNTCNAGY TCNYTNAARCARCARMGNTCNACNACNGTN------AARTCNTCNGGNGGNAGYAARTCN AGYAARAGYAARAARTCNAARGCNGTNAARGCNACNATGAGYGTNTCNAAYAAYAGYAAY AGYAGY------------------------------------------------------ ------MGNAAYATHTTYYTNCARAARTAYAARYTNCAYGTNTCNTTYCARGARGARGAR CARTTYTAYCARGARTTYMGNCARGAYYTNMGNATGMGNGGNTGYGCNACNCCNCARCAR TAYGARGCNGTNYTNGCNGARATHMGNAARGARATHTCNMGNMGNAARAAYTTYCAYCAY GAYGCNTAYATHMGNTAYCARAARATHTCNGARACNTAYMGNTGYYTNCAYCCNCAYYTN TGGGARTTYAARCCNTCNTTYGTNGAYAGYATGYTNTCNAAYATHGTNTCNYTNATH--- CARATHTCNAGYAARGARGARGCNGARAARGCNATHYTNCAYAAYGGNGGNAAYGTNATH GGNMGNCAYYTNTAYMGNATHCCNGTNTTYTCNACNGAYTTYTGYAARAARYTNGTNGAR GARYTNTCNCAYTTYGARGAYAGYTCNTGYCCNAARGGNMGNCCNAAYACNATGTCNAAY TTYGGNATHTCNYTNGAYGARATGGGNYTNTCNGARGGNYTNYTNACNCCNYTNATHGCN AARTAYATHCARCCNYTNGTNACNGCNYTNTTYGGNCAYTGGTGYCARGARAARYTNGAY TCNTTYMGNTCNTTYTCNGTNYTNTAYGGNCCNGGNAARGAYACNGARYTNAGYAARCAY TAYGAYAAYGCNGARGTNACNYTNAAYGTNTGYYTNACNTCNGAYTTYGARGGNAGYCAY YTNGARTTYGGNGGNYTNTGG---GAYGARCCNGAYTCNGARAGYTAYAARGAR------ ---ACNGTNATGCAYGARATHGGNAARGGNATHYTNCAYYTNGGNCARCAYACNCAYCAR GCNYTNCCNATHGTNTCNGGNACNMGNTGYAAYYTNATHYTNTGGATGMGNAGYTCNGCN GTNMGNAAYAARTTYTGYMGNATGTGYGGNTCNAARCCNGTNGTNYTNGARGTNCCNTTY GCNGGNGAYGGNTTYACN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GTNAARATHTCNYTNAGYCARGGNCCNAAYGGNGAY YTNYTNATHAARGTNGAYGCNCCNTTYTTYAAYAGYCCNGCNAARCCNGAYGGNCCNGTN GGNCARCCNTTYCCNCARYTNTGGGAYTAYGARGTNGTNGARGCNTTYTTYYTNAAYGAY CARGAYCARTAYYTNGARGTNGARYTNAAYCCNCAYGGNCARCAYYTNYTNYTNYTNYTN AAYGGNMGNMGNAARATGGTNAARGAYAARYTNCCNYTNAGYTTYACNGCNACNATHAAR GGNGAYAAYTGGAGYGGNGARGCNGTNATHCCNAARGAYTAYYTNCCNTCNTCNGTNACN AARTTYAAYGCNTAYGCNATHCAYGGNGARGGNGAYGARMGNGARTAYGARGCNYTNTAY CCNGTN---------ACNGARAARYTNGARGGNATGCARCCNGAYTTYCAYMGNYTNGAR YTNTTYCARCCNYTNGAYATGAGYGCNATHYTNAGYAAYTAYGAYGCNACNCAYGTNTCN CCNYTNTGG--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNAGYTAY TCNAGYATHCARTCNATHAARGARGARCAYTCNMGNATHAARCARGARCARGGNCARGCN AARTCNTCNAAYACNGARGARTCNAAYACNYTNTTYGARAGYYTNMGNGAYACNATHTAY ACNGARGTNGCNTCNYTNATHTCNCARAAYGARAAYMGNCCNCAYTTYCARCCNAARYTN GGNGARGGNGCNTTYYTNGCNTCNGARCAYYTNYTNMGNCCNAARGGNTCNAARCARAAR ACNAGYGAYTCNGGNAAYCAYATHGAYCCNGAYATGGCNTAYGGNGAYGGNGCNAGYAAY TCNGGNGTNGAYCARGCNAGYGARAGYTCNATGTCNGAYATGCCNTAYCCNMGNATHGAY ATGAARCARYTNGAYYTNCARATHAARCARGTNATGATGGARACNATHCCNGTNGTNAAR GARCAYATGGARGAYATHTGYTCNAGYCARYTNYTNGCNTAYATHAARMGNYTNGTNYTN TCNYTNACNGCNCARACNGGNAAYCARGARTTYGCNMGNTTYTTYCAYMGNCARYTNTCN TCNATHYTNCARGAYACNYTNGARAARTAYGARGGNMGNAARATGMGNGARTGYGGNGAR GAYYTNYTNGTNGARATHTCNGAYGTNYTNTTYAAYGARYTNGCNTTYTTYMGNYTNATG GARGAYATHGARGAYCCNAAYGARGTNGARMGNYTNMGNGCNTAYCARGGNAARMGNAAY CAYAGYCARMGNGTNGARGAYGARAAYGARGARGARGAYAGYAGYTTYAAYGARGAYGGN GAYATGGAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AGYTCNCCNMGN GARTAYYTNMGNACNCCNCCNGTNAGYCCNTCNCAYTAYACNATHAARGGNTCNTCNGTN ACNCCNACNATHCAYACNGCNCAYTCNCCNTTYCCNACNCCNGTNTCNTCNGCNTCNTCN GCNCCNAAYAGYCCNTCNTTYAAYGTNGAYTTYCARGTNTCNGAYCARGAYYTNGCNYTN ACNTCNATHCCNGGN--------------------------------------------- ------------------------------------GTNAGYTTYGAYCCNMGNAARMGN AAYTTYTCNGARGARGARYTNAARCCNCARCCNATHATHAARAARTCNAARAARNNNTTY GTNCCNGAYGARYTNAARGAYGAYAARTAYTGGGCNMGNMGNYTNAARAAYAAYTAYGCN GCNAARMGNTCNMGNGAYGCNMGNMGNGTNAARGARAAYCARATHGCNYTNMGNGCNGCN TAYYTNGARAARGARAAYAARTGYYTNAARGAYGARATGGTNAARYTNMGNAARGARAAY GCNAARYTNAARACNATHGCNGAYAARTAYGARCCNGGNGCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------MGNACNATHACNCCNTTYCAYAAYAGYMGNMGNMGNCCNCARACNTCNCAY ---CCNMGNTTYCCNCCNAAYACNTAYAAYGAYCCNGGNMGNTAYTCNAARGGNGAYGTN TTYGAYGTNMGNGARACNGAYGGNGTNAARAARCCNMGNCCNGTNAGYGCNTCNAGYYTN MGNGARGCNGAYGCNGCNMGNGCNMGNCCNMGNTCNGGNTCNTTYTCNAARMGNGAYAAR CARTCNCARGCNTTYATHACNCARAARAAYGARMGNTCNYTNMGNTAYGARGCNACNAAR CCNGTNTAYGTNTTYCCNAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CAYAAYCARYTNGARAARAAYMGNMGNAARCARATGMGNGARTGYTTYAAYTAYYTNCAR CARTGYATHCCNACNYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNYTNYTNACNTGYGGNGGNACNATHGAYAARCARTAYCCN CARGGNCCNGGNGCNTAYTCNTTYGARTTYGGNGARGCNGCNGTNGARAARATHYTNGGN MGNATHTGYCCNTCNTTYCAYTAYCARATHGARAGYATHTGYACNAARGAYAGYCARGAY ATGACNGAYAGYGAYMGNGARGAYATHYTNMGNGCNGTNGTNGAYGGNGAYCARCAYYTN GTNYTNGTNACNCAYGGNACNGAYATHYTNTGYGAYACNGCNCAYTAYYTNGTNAARGCN GGNGTNGGNCARGGNCCNCARTTYGGNCCNGGNGTNGGNGTNAARACNGTNATHYTNACN GGNGCNTTYAARCCNGARGTNATGAARGARTCNGAYGCNGAYTTYAAYATHGGNTTYGCN YTNGGNTTYYTNCAY---TCNTGYACNCCNGGNGTNTTYGTNGCNATHGARGGNAGYATH YTNGAYGGNTCNCAYGTNATGMGNTGYGARGAYGGNAARTTYGTNGAYGARMGNCAYGTN YTNAARMGNTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATHTTYYTN TTYGGNYTNTAYGARAGYGTNACNGAYAAYTCNTAYTCNAAYGCNACNTCNYTNTCNCAR ACNYTNAARGAYGTNYTNGGNGAYGTNAARAARGCNTTYGAYAAYGAYGTNACNCCNTTY TTYGCNYTNTTYATHTGYGCNTGGGGNACNGTNTTYYTNGARATGTGGAARMGNCARTGY GCNACNYTNGCNTAYGARTGGGAYGTNGAYCARTAYGARGAYAAYGARCCNGAYMGNCCN CARTTYTAYGGNACNAGYGTNAAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYATGGAYCARTTYMGNAAYGCNYTN YTNGARGCNTCNGGNYTNGCNMGNTCNTTYACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGYTNTCNMGNTCNGGNMGNGCNGARACNMGNAGYMGNGCNAARGAR GAYATHAARMGNGTNATHAAYGCNATHGAYAARGTNMGNAARTGGGARAARAARTGGGTN ACNYTNGGNGAYACNTCNGTNACNATHYTNAARTGGGTNCCNGTNACNGCNCARGARAAY CCNGGNGCNYTNMGNAARATHCCNGGNGTNAARACNAARACNTAYTCNAARGCNMGNGTN GARMGNGARMGNGARYTNTAYAAYGCNGARACNAAYGGNGGNYTNMGNGCNAAYTCNCCN GCNGAYTCNACNAGYAAYAAYACNAAYYTNTCNAAYACNAGYTCNCCNACNTCNAARAAY CAY------AAYACNGARAARCCNAARAAYGGNACNGTNACNAAYAGYCARGGNTCNGTN ATGTAYTCNGARGARAAYACNCARCARTCNATHGGNTCNTTYGGNTCNGARAAYYTNAAY GARGAYTCNAAYATGTCNTTYCCNGARAAYAGYGGNYTNAGYGARCARGGNGAYCAYAAY GARTTYTCNCAYGAYAGYAAYGAYGCNGAYCCNGGNATGMGNGTNGCNATGAGYATGGTN GGNGAYGARGAR------------------------------------------------ ------------------------------------------------------------ ATGTCNGARAARCAYAAYTTYGGNATHGCNCCNGTNACNTGYCAYGCNTTYAGYAARGAY MGNAAYGGNYTNGCNATGTCNYTNAAYGAYTCNAAYGTNAARATHTAYAARAARGCNGGN AAYAARTGGGAYGARACNGAYACNYTNAGYGARCAYGGNCARMGNGTNACNAGYATHGAY TGGGCNCCNAAYAGYAAYMGNATHGTNACNTGYTCNGCNGAYMGNAAYGCNTTYGTNTGG ATGTTYGARGAYGGNAARTGGAARCARGTNYTNGTNATHCCNMGNATHAAYMGNGCNGCN ACNTGYGTNAARTGGTCNCCNAARGARAAYAARTTYGCNGTNGGNAGYGGNTCNMGNYTN ATHGCNATHTGYTAYTAYGAYGAYGARAAYAAYTGGTGGGTNAGYMGNCAYATHAARAAR CCNATHMGNTCNACNGTNACNTGYYTNGAYTGGCAYCCNAAYAAYGTNYTNYTNGCNGCN GGNTCNACNGAYTTYAARTGYMGNGTNTTYTCNGCNTAYCARAARGARGTNGAYGARMGN CCNGGNGCNTGYAGYTGGGGNACNAARATGCCNTTYGGNGCNYTNATGGCNGARTTYAGY AAYGGNGGNGGNGGNTGGGTNCAYTCNGTNTCNTTYTCNCCNAGYGGNACNMGNGTNGCN TGGGTNGGNCAYGAYTCNAGYGTNTCNATHGTNGAYTCNTCNAAYGARAAYGARYTNGTN GTNGTNAARGARAGYTTYYTNCCNTTYATGAGYATHTCNTGGGTNACNGARAAYTCNYTN GTNGCNGCNGGNTAYGAYTGYAAYCCNATGATHTTYTCNTTYAGYGTNGGNAARATHACN TGYCARGGNAARYTNGAYGTNCCNCARGARAARGARTCNGGNACNATGAGYGCNATGAAY MGNTTYAARAAYYTNGAYAARAARGCNACNGAYAGYGAYAGYTCNCCNGARATGAARACN CARCAYCARAAYACNATHACNCARGTNTCNATHCAYACNGGNGAYAARCARAAYGCNAGY AARATHGCNACNAGYGGNGTNGAYGGNAAYYTNATHYTNTGGGAYYTNAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ---ATHGARGTNGTNAARACNGARTGGAAYGCNAARTCNAARGTNGGNTCNYTNGAYAAY GCNAGYCAYMGNCCNGGNGGNGGNGAYAARAARATHGARACNCARAARACNGAYTGGAAY GCNAARTCNMGNATHGGNTCNYTNGARAARGCNAAYCAYAARCCNGGNGGNGGNGAYAAR AARATHGARACNGTNAARACNGARTGGAAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNGAYAAY YTNAAYGAYMGNMGNATHGGNGTNGTNYTNTTYGARTTYMGNACNTGGYTNGAYGCNTTY GAYGGNACNATHTTYMGNGCNCARCCNGGNAAYCAYYTNAARTAYAAYTCNGTNCAYGCN ACNYTNGGNTAYTAYATHGAYTCNTCNTTYGAYAGYYTNGGNGGNGCNTTYYTNTGYTTY GGNATHTAYTTYTAYATGYTNAARAARTTYGGNCCNCCNMGNATHCARTGYGCNYTNCCN TTYTGGTCNTCNACNTCNGARGTNCARAAYAARGTNCCNYTNGTNAGYGAY--------- ---GGNGGNAARGARACNTAYTCNGCNYTNTAYYTNTTYTGGAARGCNTTYTCNTTYGGN YTNGTNYTNYTNGTNGGNGCNGGNGCNTGGGAYAAYATHGTNGTNCARTTYTCNGAYGTN TTYCARACNGARYTNAARGAYCCNAGYTCNGCNGCNYTNCARYTNGARYTNTCNCAYGCN AAYACNACNGTNTTYATHTTYCARYTNTGGMGNYTNATHGGNTCNCARTGYATGYTNAAY TAYATHYTNYTNATHATHTTYTTYGAYAARATHTGGGARTTYYTNAARGGNACNCARTAY ATHYTNYTNGTNGTNATHGTNAGYYTNTAYGTNATHTCNGTNYTNTAYGTNAAYCARATH MGNACNCARYTNCAYATGCCNAARYTNATHGTNTTYGAYYTNGAYTAYACNYTNTGGCCN TTYTGGGTNGAYACNCAYGTNAGYCCNCCNTTYAARAARGARTCNGAYGGNAARATHMGN GAYGCNMGNAAYAGYMGNGTNAARTTYTAYCCNGAYGTNCCNGCNATHYTNGCNAGYYTN CAYTCNCARGGNTAYAARYTNGGNATHGCNTCNMGNACNAGYGCNATHGARGAYGCNGAR GAYYTNGTNMGNYTNTTYGAYTGGGAYAARTAYTTYCAYTAYMGNCARATHTTYCCNGAY TGYAARATHACNCAYTTYAARGGNYTNCAYAARATGAGYGGNATHCCNTTYTCNGAYATG YTNTTYTTYGAYGAYGARCAYMGNAAYATHAARGAYGTNTCNAGYYTNGGNGTNACNTGY ATGTTYGTNCCNGAYCAYGGNYTNACNAAYGARTCNYTNGTNGARGGNYTNGARYTNTTY AARACNAAYAAYAARAARMGNGGNTCNACNTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TCNCAYGAYAARTAY YTNCCNTAYMGNCCNCCNGGNTCNAARCARGTNTAYTAYATHGARAGYGAYACNGCNTCN GTNGCNGAYAGYGTNACNACNYTNGARAGYACNCAYATHGGNTCNGAYGAYGCNAARGGN CCNACNYTNCCNTCNCAYGCNTTYGGNTCNMGNAARGAYCCNCCNATHGCNTCNGGNATH TAYAGYTCNCAYGAYYTNTCNACNGTNMGNGARGAYACNGARYTNGGNACNATHGARGAR AARTTYATGAAYGAYTCNGGNAGYAGYTCNATHAAYAGYTCNAARATHGARGCNGTNGCN GAYYTNYTNAARAGYCCNTCNMGNCAYYTNGTNTCNCARTAYGTNAARGAYMGNGARGAR TAYMGNATHGARMGNCARGARMGNGCNGARYTNGARMGNGARCARMGNYTNCARGARCAR CAYATGAGYTCNAGYGARGAYGARATHAAYGARMGNTAYGCNGARYTNYTNGCNYTNAAR GARGARGARMGNATGAARMGNMGNGTNGCNAARAARAARAARGGNMGNGAYAAYYTNTTY TCNATHCCNGARGAYMGNAGYCAYGAYCCNTCNCCNACNAARACNAAYACNCCNTCNCAR AAYCARAARTCNAARGGNACNMGNCARGCNCAYGTNATHGAYCCNAAYATGTTYAARYTN MGNGARMGNATHGCNAARCARAARACNAARGTNGAYAARGAYATGYTNAARGARATGMGN MGNATHGARAARYTNAARAARYTNGARAGYYTNYTNAGYGCNAARAARACNGGNAARATH TCNTCNGARAAYGAYGCNCCNMGNCAYAARGAYCARGTNGTNAARGARTCNGTNTCNTGG CAYATHCCNATGGAYYTNCCNCCNAGYCARTGGAARGARCCNTCNAARTGYCCNCARMGN CCNYTNMGNGARGTNGTNACNAAYACNACNGARAARCAYTCNGARACNGCNCARMGNTTY AAYAGYGTNCARAARGAYMGNAAYAAYTGYGGNAAYCAYAARAGYGGNATHTGGACNATG AAYAGYCAYCCNAARGGNATHCCNAARYTNCARTGGGARMGNGTNGTNAGYTCNGAYGCN YTNGCNACNAARACNAAYCAYTGGGARGTNGAYCCNATGATGGAYMGNGTNCARTAYATH YTNAAYAARCARGGNTCNGGNGAYCCNTTYTAYGGNGGNGAYAGYGAYMGNTAYGARAAR CCNGTNTCNAARATGTCNYTNCARGARGCNTTYATGATGMGNAARCARMGNTTYATHTCN AARTGYTCNGARMGNCARAARMGNYTNAARYTNGCNAARGARGAYMGNCARYTNCARGAR TGYYTNMGNYTNGARMGNGARGCNATHTTYGCNGARCARCARMGNYTNGCNCCNCCNAAY YTNTAYGCNCAYCCNTAYAGYGAYAAYYTNCAYCARCCNAARCAYMGNATHYTNACNAAR CARGARATGAARTCNYTNACNGCNAARMGNTAYAAYAARYTNCCNGARGTNYTNGGNAAR AARGARGARAAYAARAARCARATHGARGCNAARYTNAAYMGNYTNMGNGCNAAYYTNTTY AAYAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AGYGCNATHAAYTGY TCNAAYAAYMGNGTNMGNMGNCCNGAYYTNTCNTTYTTYMGNTTYCCNYTNGARCCNGAY MGNTGYAARAARTGGATHATHAAYTCNCARMGNTTYGAYYTNAARGGNAARTCNTGYAAR ACNYTNCAYAAYGGNAAYACNATGTGYTCNGARCAYTTYGAYAARAARTGYATHMGNGTN AGYCCNAAYTCNGTNMGNCARMGNYTNTTYMGNTGGGCNGTNCCNACNATHTTYAAYTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGMGNATHTAY AARTGYYTNYTNACNGGNGAYGARATGTTYTCNGAYACNTAYCCNATGAARGARGCNGAY GGNTTYTAYATHGTNAARGGNAARTAYGTNACN---MGN---AGYGAYTCNGTNGAYGAY AGYYTNATHGGNGGNAAYCCNAGYGCNGARGARGCNGARGAY---ACNGCNGARGAYGGN GCNGARTCNGGNATHGAYATHGTNYTNGAYTCNMGNYTNAARGARACNGGNTTYGGNACN AARAARGARTAYACNGCNTAYATGAARGARTAYATGGCNAGYGTNGTNGAYAARYTNAAR GARAGYYTNTCNGARGARAARGTNACNGARGCNAARYTNGARGCNAAYGGNGCNTTYAAR ACNGCNYTNGGNAARTTYAARAGYTGGCARTTYTAYTCNGGNGCNGGNGAYAAYCCNGAY GGNCAYATHGCNYTNYTNGAYTGGYTNGAYGARGARGTNGAYGGNAARTCNGTNTCNACN CCNTAYATGTAYTTYTAYAARATHGGNYTNGTNTCNGARAARGGNGCNGTNGGNTGYMGN AGYCARAAYGARYTNATHGAYATHATGGAYGGNTTYAARGCNGGNACNTTYTCNATHGGN GAYGCNGARATGYTNYTNAAYGCNTGGAARGARMGNAAYGAYGGNGGNAAYMGNGCNATG AGYTTYAARGGNMGNCARACNGCNYTNCARAAYATGMGNTTYAARACN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARMGNYTNMGNGAYAAYGARATHTGYAARAARGTNGAYATHGARAARGCNGARCARAAY TAYYTNATHGAYTGYGARAAYGCNCARAARGARTTYGARGARAARMGNGTNGCNATGAAR GARAGYYTNATHAAYCAYYTNAARGARAARAARATHGAYYTNAARGARACNYTNATHTGY GAYYTNAARGARAARMGNAGYGTNATHGARYTNGARMGNCARACNGTNGAYYTNAAYGGN GCNGAYTTYATGGARGTNAARCCNACNATGACNMGNAARYTNMGNMGNMGNCCNAAYGAY CCNATGCCNATHCCNGARAARMGNMGNAARCCNTCNCCNGCNCARGTNAAYATHYTNYTN GARGAYGAYYTNATHYTNGCNGAYYTNMGNYTNATHATGAARGTNAGYGGNAARCCNATH GCNAARAARCARGGNYTNGGNAAYCAYAGYCCNATHATHGAYACNTCNTCNGAYGTNMGN ATHGARGAYGGNMGNYTNTGGTAYGAYAARAARTGGTTYCARMGNAAYACNATGGTNCAR ATHGAYAAYAARGARACNGGNTCNMGNATHCAYGGNACNATHACNAAYATHYTNAAYCAR GARATHTGGGTNAARAARAGYGGNGAYAAYTCNAARYTNMGNATHATGYTNAAYCARTTY CARAARGGNAARTAYAAYATGAARAARMGNACNACN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GARATHAARCARCAYCARAARTCNGAYTCN ACNTTYGAYGARAARYTNYTNYTNGCNMGNAARCARYTNYTNGGNYTNGTNCCNACNATH CAYMGNTTYAARCAYCAYGCNGCNGTNACNMGNATGTCNMGNGCNGCNCCNTCNAARACN MGNGGNGCNGAYAARACNAARCCNCCNGCNTCNCARACNCCNGTNATHGCNCAYGARATH GTNCCNGGNAARTTYAAYGAYAAYGAYTGGAAYCAYATGYTNGARMGNGAYGGNGGNGAR GARTTYGTNYTNGAYATHATGGAYGAYYTNATGGARAARACNATGGCNACNATHTAYGAY AARTAYATHGARMGNCARYTNYTNCCNTTYACNATHACNCARGCNAARGAYGCNATHATH GARATHATHGARTGGCARTTYYTNATHMGNGAYGARGGNGARGARAAYATHGARGCNGAY YTNGGNTGGACNCARGAYGARGARCCNGARCCNGCNGARACNGAYTGYTGGGCNCARGGN TCNGTNCCNAARAAYGTNATHYTNGCNCCNTCNCCNGARYTNGARGARATHCCNGARGAR ACNGARGARGTNCCNCARGARGARGARAGYAARGARGCNCARGCNGARGARGARCARGAR GARGARGTNGARCARGARCCNCCNGARYTNGAYGAYATHGTNTCNGARGCNGARGARACN TCNCARGTNGTNGAR---GARCARAAYGARAARGAYAARGARAARGARAARATHCCNTTY CCNCCNAARGTNTCNGTNTCNTCNMGNAARAARTTYMGNCCNTAYMGNGGNAARYTNAAR TCNGCNGGNGTNAGYAARATGACNGARTCNYTNGARGARACNGARATHAARATHATHTAY GAYGARATHGTNGCNTCNATGCCNCCNAGYGARGARMGNCCNAGYACNYTNYTNAAYATG CCNGCNTCNTGYACNAGYATHYTNAARGTNCARACNGGNMGNCCNCCNGGNAAYAARGAY GTNGTNTAYGAYGAYYTNGGNAAYGTNGTNGCNGTNATGAARYTNGAYCCNGARAARYTN CCNACNCAYAARGTNAAYGTNAARTAYCAYGTNGTNGAYCCNGCNGTNGARGCNGCNCAR GCNMGNYTNGAYGCNATGMGNAARGGNAARTCNACNGGNAGYAARATGMGNAARYTNAAR TCNATHAARAAYYTNCCNACNGARGCNCCNAAYTCNGGNTCNAARGCNAARGTNACNACN AGYCARAGYGCNGTNACNTCNYTNCCNCCNCCNYTNCARACNGGNAARMGNTCNGTNGAY CARTCNMGNGCNGCN------AARCCNTTYMGNATHGARGARATGGARGTNTCNCAYGGN GTNATHGTNMGNGARGGNGGNMGNGTNAARAARGGNCCNGGNMGNTAYTAYMGNAARYTN GAYGTNYTNGARGARCAYCARAARGGNATGAARCCNGTNAGYGTNMGNYTNAAYAAYACN GGNATHACNGTNAAYGAYYTNYTNGAYMGNAAYACNCCNATHYTNMGNCCNYTNGCNGAR CARTCNCCNYTNCCNCCNATHATHCCNCARCCNCCNCCNCARCCNCAR---CAR------ ATGGTNAARATHGCNGTNATHGGNGCNGGNATHGTNGGNTAYAGYTCNGCNYTNAAYYTN CARMGNGTNYTNCCNGGNGCNCARGTNACNATHATHGCNGAYCARTTYGGNGAYCARYTN GTNTCNACNGGNGCNGGNGGNGTNTTYMGNCCNGARYTNGGNCARYTNGTNCARGGNGAY AAYGARAARYTNATHAARCARTGYYTNMGNGARTCNTGGGCNCAYTAYACNACNYTNGCN GCNTCNGAYCARGCNAARGARTCNGGNCARATGATGGTNTTYGGNYTNTTYTCNCAYMGN MGNCCNATGGARTAYGAYTAYTCNGTNYTNAARAARTGYGCNTTYGAYTTYMGNMGNATH TCNGAYAGYGARMGNMGNGCNMGNGGNATHCCNGARGAYTTYAARTAYACNTAYGCNTGY ACNAGYGTNATHTCNCARACNTCNATHTAYATHCCNTGGYTNAARAARCARTTYGARGCN AARGGNGGNAARATHCARGTNMGNACNGTNAARAARYTNGARGARYTNTAYCCNGARTTY CARATGGTNATHAAYTGYTGYGGNATGMGNGCNMGNACNTTYYTNGGNGAYACNGARTGY TTYCCNACNMGNGGNCARYTNGCNMGNGTNCARGCNCCNTGGTTYAARCAYTAYCAYTAY TTYGAYACNGAYATHTAYATGATHCCNCAYATGGAYAARYTNAAYATHGGNGGNATHMGN ATHCAYGGNGAYGGNAAYACNGARGTNGAYCCNGARGTNACNCARACNATHYTNAARMGN GCNMGNGAYYTNTAYCCNCARYTNAARGGNGCNGARYTNATHTCNTCNTGGGCNCAYTCN MGNCCNGGNMGNAGYAARCCNMGNATHGARYTNGARMGNYTNAARATHGGNAGYGGNAAR GARYTNATGGTNATHCAYAAYTAYGGNCAYGGNGGNAAYGGNATHACNYTNAGYTGGGGN TGYGGNGCNCAYGTNGCNMGNATGGCNAARGARGCNYTN---ATGGAYGARGAYTCNCCN GCNGTNCCNGGNTCNCCNCCNYTNCCNAARAARGGNGCNTAYAAYATHGAYTTYGAYCAY YTNGAYGARTTYTCNAAYCCNTTYGARTCNAARAGYAARGTNGARATGGGNTCNTCNCCN CCNATHGAR---------------CCNAGYGCNTTYGAYTTYGAYGARCARGCNGAYCCN TTYAARTCNAARAARTCNYTNGCNAAYTCNCCNCCNGGNTCNCCNAARAAYAGYGTNMGN AAYACNGCNGARATHAGYACNGAYYTNAAYCAYGGNGGNGAYCARAAYAAYGAYYTNCCN CARGARTCNGGNGGNGTNCCNGARCCNGCNTCN------GTNGARGARGARAARAGYTCN CARATHACNCCNAARAARAARAARGTNATHAARAARCCNCARTCNYTNTCNAARYTNAAR CCNCCNAARAGYGTNAARMGNAAYAARAAYTGYGARGAYGTNGARATHYTNATGCCNAAR ACNGGNYTNTAYTGGGTNGAYATGGGNYTNGAYTGGMGNCCNMGNTAYCCNMGNTAYTCN ATGACNTTYTAYAARAAYYTNATHCARGAYMGNGGNYTNACNAAYCCNACNYTNGAYTAY MGNGCNTAYCCNGCNGAYMGNGAYACNTTYTAYTAYGGNAAYTTYCCNTCNAAYTTYYTN TGGGGNGTNGCNACNTCNGCNTAYCARATHGARGGNGGNTGGAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGGMGNATH GCNAAYYTNATHATGGCNGTNTTYTTYYTNYTNGCNGGNYTNGCNAAYACNAAYGAYAAY GAYTGGTTYATHTGGACNCCNATHTAYYTNGTNGCNTCNGTNYTNTGYTTYYTNGCNTTY ACNTTYTCNACNATHATHGGNAAYCAYYTNTGGCARYTNATGATGTCNATHCARYTNGGN GTNGCNATHGTNATGGGNYTNTAYCARGTNTCNYTNGTNTTYGGNGTNGTNCAYAARATG GGNACNAAYCCNYTNGTNYTNGARGARGGNMGNGARATGGGNGGNATHATHATHATHYTN GTNTGGACNGGNATHTCNMGNTTYTCNCCNTTYAARAGYGCNGGNCCNCARGGNTCNTCN AAYYTNATGACNGGNYTNYTNGCNGTNTCNYTNACNYTNGCNGTNGTNCCNYTNATHATH TGGTCNYTNTGYTTYGTNGGNGAYTGGCAYAARCAYYTNGGNCAYTGYTCNGGNATGYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CCNTTYAARTCNTGG GARGAYYTNTGYGCNAARTTYGAYAGYACNAARCCNYTNTCNACNGCNYTNATHTCNGGN TGYAARGARATHATGMGNGTNMGNAAYATHATHMGNMGNYTNATGATHMGNTGYGARAAY ATGTCNCARCARATGGARAARGTNGTNTCNACNYTNACNGARAGYCARCARAGYGARGGN YTNAAYGAYAAYGGNMGNATHGTNMGNCARCCNCARYTNYTNAAYAAYGAYTTYTCNYTN AARCCNTAYCARYTNATHGGNYTNAGYTGGYTNMGNYTNATGCAYGARCARGARYTNAAY GGNATHYTNGCNGAYGARATGGGNYTNGGNAARACNATHCARGCNATHTCNTTYYTNGCN CAYYTNYTNGARGARGARGARGARGGNCCNCAYGTNATHATHGTNCCNTCNTCNACNATH GARAAYTGGYTNMGNGARYTNCARACNTGGTGYCCNGCNYTNAARGTNATHGTNTAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TAYAAYATHGGNATHYTNGGNGTNAARAARCCNYTNGARTGYACNTGYCARGAR YTNYTNTCNACNACNAAYGTNGTNATGAAYGGNTGGYTNMGNAARMGNGCNYTNMGNAAY AARATH------ATHACNATGAAYTGGCCNCARATGTAYGTNATHGTNGCNAAYCARTGY YTNTAYTAYTTYTCNAGYGARMGNGCNAARAARGCNTCNGGNTCNYTNTCNTTYTAYGGN TTYAAYMGNATHTGYMGNGCNCCNAGYATHAARGTNAARGAYGTNGTNTGGGCNTTYAAR YTNGARCAYATHCARCCNAAYATHMGNTCNYTNTAYTTYTCNGCNTCNTCNGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGGCNGAYTCNAARTCN AGYYTNGCNMGNGAYGGNACNATGCARGTNACNGCNAARGARGGNATHGAYTAYYTNAAR TCNGCNCAYAARGAYACNYTNYTNAARGTNCARGGNYTNGTNAARGAYAARCCNGCNGTN CARMGNGAYGGNACNATGGTNTCNACNGCNAARGARGCNGARMGNYTNYTNGAYGGNAAY AARCCNGAYGCNGAYGCNCARACNMGNGGNCARCARAARCARATHGARGAYYTNAARAAY GCN---GARCCNCCNAARGCNAARAARGCNMGNYTNGCNAARGAYGGNACNATGGCNGTN ACNGCNAARGARGCNAARTCNYTNYTNGCNGGNGARAARYTNGGNGAYACNMGNCARGAR ACNAARAAYAARACNGGN------AARACNCCNYTNMGNAARGCNAAYACNATGGCNMGN ACNGTNGARGARGCNAARAGYGTNYTNGAYGGNAARGTNGAYYTNAGYGARGGNMGNAAR ACNMGNTCNCARAGYMGNGGNGARGTNCCNAARCCNTCNATHAARAARATGGGNACNATG CARCARACNGCNAARGAYGGNAARGCNTTYYTNAARAARAAYAARGGNAARAARMGNGCN ------GCNGCNAARGCNGAYGAYGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGCCNAGYYTNCCN YTNATH---------------------AARCAYACNATGGCNGCNGTNGGNGCNAGYACN GCNMGNGCNYTNAARCARATGATGAARCCNCAYATHCCNATGATHMGNTTYCCNAARMGN GGNTCNCARAGYGARYTNCAR------GCNACNTCNGGNGGNAAYACNAGYTCNYTNGAY GTNYTNYTNACNAAYAAYGTNACNTCNGGNCAYCCNGCNCCNGCNAGYGGNTCNAARAAR GTNAARGGNCCNTCNATHGAYTCNTCNGARYTNCCNATHMGNTTYCARMGNAARCCNATH TCNAAYGARGARATHGARTTYATHGARAARGGNGGNCCNGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CARGGNGARGCNAARAARMGNMGNGGNYTNMGN MGNYTNTTYGGNMGNYTNAARMGNAGYAGYTCNCARGAYYTNGARGGNTCNMGNGAYMGN MGNGAYAAYAAYGGNGAYTTYMGNMGNGGNGGNGTNMGNGCNACNGCNACNGCNMGNYTN GCNTGGAAYMGNGAYGTNAARGGNMGNATHTCNAGYCCNGAYATHCCNTTYGCNMGNTGG GAYACNGAYMGNATHACNGCNTGGYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNAGYATHCAYACNCARGTNTCNCCNYTNYTNTTY CARYTNTCNGARAARYTNTGYGGNGARCCNATGAARAARMGNAARACNAARGAYCCNCAR ATHGTNATHGCNMGNACNCARAARMGNYTNAARAARATHGAYAARGARATHAARMGNYTN TCNMGNTTYGCNAARACNATGAARCCNGTNGARGARATHGARGTNGAYMGNMGNAARYTN ATGTCNACNGGNGARMGNMGNMGNGARCCNACNGTNYTNACNTTYGARGARTCNGARTCN MGNGCNYTNYTNCAYAARGCNTGGACNTCNTAYMGNACNAGYTGYCAYCAYGARYTNYTN AARACNTTYACNYTNGTNTGYGCNGCNCARCARGARGCNYTNGAYGARYTNMGNGCNGAR TCNGARGARYTNTAYCARGCNGCNATHCARAARGAYGARAGYATGYTNCCNTTYACNTTY GARGGNCCNAARGARACNCCNCCNATHAARGAYTAYGAYGCNCCNGAYGGNGARTAYATH GAYACNACNMGNAARTTY---------------GAYGTNGARTGGAAYATHGAYATGGAR GTNAAYYTNTTYCAYGCNATGMGNGGNCAYAARCCNGCNGGNGTNAAYMGNCAYTTYCAR ATGATHGCNATHCAYGAYAARYTNAGYTCNTCNACNAARAARGTNACNTCNAGYGAYGTN TGGAARCAYYTNTCNACNYTNTAYGAYYTNCARGCNYTNTAYGARTCNGARATHGTNCCN TTYCCNAAYAARAAYGGNGAYTTYGCNYTNGTNGAYMGNGARATGYTNGAYYTNTGYACN MGNTCNTTYCCNMGNTCNTCNTAYATHAAYGCN---CCNAGYGARCCNGCNAARCCNGAR GCNGGNAARACNATHTCNAARTTY---AGYACNAARCARGAYAGYAARCARGTNTCNCAY ACNCCNAARTCNGAYGCNAARAGYGARCAYAAR---TCNTCNAGYAGYTCNAARTCNGAY AGYMGNTCNAAYACNCCNTCNAGYMGNTCNGARTCNAARTCNTCNCARCAYAAYAGYAGY AGYGCNGTNAGYACNAGYAGYTCNAARTCNTCNCAYCARAGYACNCCNACNTCNGCNCCN TCNCCNTCNCCNAARMGNACNAARMGNACNMGNAAYGTNAAYTCNGCNTCNGCNAGYCCN GCNACNCCNACNGARCCNCARTCNAARMGNMGNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGCAR YTNTTYMGNGTNYTNMGNATHTTYMGNYTNATGMGNCARATGCCNGGNYTNTGGATHYTN GTNTAYACNYTNAARTCNAGYGTNAARGAYYTNYTNYTNYTNYTNYTNTTYYTNTGYGTN GGNACNYTNATHTTYTCNACNYTNGTNTAYTTYGCNGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNAARCAYCARTTYCARCARYTNCARGARCARCAR CARCARAARYTNYTNGARMGNMGNAARAARAARGARGARAARAARAAYAARAARGGNACN GARGARAARGAYAGYAGYACNGGNAGYTTYAARGTNGARGAYGAYYTNAAYYTNAARYTN GCNGARCAYTCNAGYAARGGNTAYGGNTAYGTNTCNGARGARYTNGTNGAYCAYYTNAAY GAYCARATHMGNCARYTNAARGAYGARAAYGGNMGNYTNTAYAARYTNYTNAGYGARAAR GAYTTYGARATHMGNCARTTYAARAARAARAARGARGARCARGCNTCNAAYACNATGGAY YTNTCNGTNACNAGYGARACNGCNGCNACNAARATHGTNGARYTNAGYAARAARGTNMGN GARYTNACNGCNGARAARGARTCNGARAARACNMGNTGYAARCARTTYCARAARAARTGY CAYGAYYTNCARYTNCARYTNCARTCNCARCCNCCNACNYTNGAYAAYTCNTCNGTNATG GGNTCNATGGTNAGYYTNMGNTCNCARGGNGAYACNMGNGARGAYGAYGGNGTNGAYGTN AARGCNYTNCARGAYMGNYTNAARCARTCNGARTCNMGNYTNTCNGAYTTYMGNAAYCAR TGYCARCARYTNMGNCARGARYTNAARGTNGCNCAYAARGTNYTNTCNCARGARATHGGN GARACNGTNAAYATHCARTCNYTNYTNAAYGARACNAGYCARTGGMGNGGNMGNGCNCAR CARATHATHGGNYTNCARCARAARATHGARGARYTNAARATHMGNTAYGAR------GGN CCNCCNGTNGTNGAYCARYTNGGNGAYAARGTNTCNACNGCNMGNMGNMGNCARGARGAY MGNTAYMGNGARGARYTNAARMGNGCNGARAARGARAARAARGARGCNTTYGARATGTCN ATGACNAARYTNMGNGTNYTNGARGAYGAYCAYGARAARGTNAARAAYAARYTNGAYGCN TCNAARACNMGNAAYAARGTNYTNTCNAAYGARYTNAARGGNYTNAARGCNCARGTNCAR ACNYTNYTNMGNAARAGYCARAAYGAYGAYGARTTYATHGARGCNYTNATGAARCARCAR AARCARYTNAARGARATGATGGARTCNACNAGYACNAARCARAAYGCNCARCARYTNCAR CARCARCARCARYTNYTNCARATGAAYATGAARAGYCARCARGAYAAYAAYATHGTNGAR CARYTNAARYTNATHGCNGCNCARAARGARTCNCARGTNAARATGYTNGARATGGARYTN ACNCARYTNMGNAGYGCNCAYGCNTCNCAYTCNGAYCARGGNTCNGARGCNGTNACNTCN GGNTCNGTNATGTCNGGNACNGTNACNCCNGGNGCNCCNGARGAYGCNACNGCNGGNGTN GGNGTNACNTAYMGNMGNGARACNACNCARATGTCNAGYGCNMGNTCNAGYGTNMGNTCN MGNTCNMGNATGTCNAGYCARGCNACNCCNACNCCNGGNAGYCCNTCNAAYCCNAAYGCN AAYGCNGTNAAYCAR---------AARGARATHGARAAYYTNMGNTAYCARYTNCARGAR YTNACNGTNATGTCNAARGCNGTNGARGTNGARMGNGAYAARATGACNGARYTNGTNCAR GTNYTNCARACNMGNYTNACNGARGARGTNGAYMGNCAYAAYAARACNCARCARGARYTN CARGGNCARAARMGNACNGGNATHGARYTNGARAARYTNYTNGGNMGNAARAAYATGGAR GCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARGAYYTNAARGAYATGGGNACNATGATHGAYMGNGARAAR GARGARGCNGARGARAARYTNAARAAYGAYCCNAARYTNAAYAARGAYACNCARGCNYTN GARACNGARATGCARAARYTNCARACNCARTTYAAYCAYAARCARGCNAARYTNCARAAR GAYTTYMGNGAYAARATHMGNYTNGAYYTNYTNMGNTCNTCNGGNATGCCNGARTCNGAR GTNGARGARGTNATHTCNAGYYTNATGTCNAAYATGGCNAARGTNGARGARAARYTNGGN YTNGARCARGCNMGNCARMGNMGNAAYYTNGARCARMGNYTNGCNAARMGNAGYCARGCN GTNGARTAYCAYCARYTNGAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGAYACNYTNTAYTTYTCNYTNTGY------GTNTTYGCNYTNTTYGCNTCNTCNTTY GGNGAYGAYCCNYTNGARGTNACNTTYGARAAYGCNACNMGNGTNGAYGCNGTNGARGGN TCNAARYTNATHCAYTTYMGNTGYCAYYTNAAYMGNGGNGCNATGTAYGTNATHAAYAAY AARGTNGAYATHGTNCAYGTNCAYCCNYTNACNAARGARGARACNACNGTNAGYAGYGCN GCNGAYYTNGTN------------------GARGGNAGYCCNTCNTTYTAYGCNGTNAAR ATHGAYCARCAYCCNGARGAYTCNAAYTCNATGGTNYTNGAYTTYACNATHYTNTCNGTN MGNTAYCARGAYGAYGGNATHTTYAARTGYTAYGTNCAYCCNGGNGGNAARTCNAGYTCN TCNGARGARGGNTTYGCNGARMGNGARGTNGTNGTNCAYMGNCCNGTNTCNTCNYTNAAR YTNAARYTNGGNGAYTTYGAYGCNATHGARGAYTCNCCNACNGAYCAR------------ YTNCARATHGAYCAYGGNGARTAYAARATHGCNTGYATHGCNGARGGNAGYAAYCCNGCN ACNGARGAYGTNACNYTNTTYTTYCAYGGNGTNGARYTN---GAYCARAGYACNCCNATG GTNACNCCNATGGARGGNTCNGARMGNAARTTYAARACNGTNGTNAAYGGNAGYYTNAAY ATHGTNGTNAGYAAYTCNGGNCARGARYTNGTNTGY------CARTCNACNGAYTCNACN GGNCARTCNAARTCNGTNACNYTNGGNATHAGYGTNAAYATHTAYGAYCCNGTNGTNCAY TGYAAYGAYAGYGARGCNCAYYTNGGNGARGAYAAYCCNATHYTNTTYTGYACNGTNAAY CAYACNGGNYTNGARGTNGARGGNTAYTCNTAYCARATHGGNGAYACNGGNGARATHGTN AARGCNGGNGAYAAY---------CAYCCNAARAAYATHATHGTNACNGTNTCNGAYGTN TCNCCNGGNATHTCNGTNGTNTCNYTNGAYYTNCAYAARGCNGARCARCARTAYYTNGAY AARAAYTAYTAYATHYTNATHGAYATGAARGGNGGNCAYACNAGYAARGARTCNGTNMGN YTNAGYGARAARGARCCNCCNGTNTCNGARAAYGGNAAYGGNAAYGGNGGNGAYGGNGGN TCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARAARGAR GCNTGYGAYATGTTYAARATGATHCARYTNTAYATGGGNGAYMGNAARGGNAAR------ ---TTYYTNAGYATHACNATHGAYTCNTCNYTNGTNMGNTAYGGNTTYMGNGGNTTYGAY TTYGGNTCNCARAARYTNCAYAGYATGGCNAARGCNYTNAGYCCNTGYGAYTTYMGNYTN GGNGGNACNAGYGCNGAYTTYYTNACNTTYGAYCCNGAYGGNAARGARTCNCCNTCNTCN TCNAGYGCNGTNTTYTCNCARGCNGAYGAY---ACNATHYTNGARAAYGARYTNYTNTAY CARGCNTTYAARGARGARGGNAARGTNTCNACNAAYTTYACNATGACNGGNCARYTNTGG GAYCAYATGGTNAARTTYTTYTCNCARGCNGGNTGGTCNGTNATGTTYGAYTTYAAYATH TTYAARTGGAARAAYGGNYTNTGGGAYCCNAARAAYGCNGARGAYYTNYTNMGNTAYTCN GCNYTNMGNGGNTAYGAYYTNCARGCNTTYCARYTNGGNAAYGARCCNAAYGCNTAYCAY TAYAAYTTYAAYTTYMGNATHCCNGCNGCNACNYTNGTNAARGAYTTYAARATHYTNAAR GAYATHYTNTAYCARTAYCCNCARTAYATGAARAAYAARYTNTAYGGNCCNGAYGTNACN GGNAARCAYTCNTCN---TCNAGYCAY---TAYYTNCARGARTTYGTNGCNGCNGGNGGN AGYYTNGTNGTNGAYGARATHTCNYTNCAYCAYTAYTAYYTNAAYGGNMGNTAYGCNAAR GCNGARGAYTTYTAYAAYATHGCNGTNATGGARAARYTNMGNGAYGARATHGARYTNGGN CARMGNTTYGCNAARGGNAGYCCNATHMGNYTNACNGARACNTCNTCNTGYTAYGGNGGN GGNGCNCCNGGNYTNTCNGAYGCNTAYGTNGCNGGNTTYYTNTGGYTNGAYAARYTNGGN YTNGCNGCNAARTAYGGNGTNACNMGNGTNTTYMGNCARACNTTYTAYMGNGGNAAYTAY GCNYTNYTNTCNCCNACNYTNGAYCCNAAYCCNGAYTAYTTYYTNTCNYTNYTNCAYAAR MGNYTNATHGARGGNCCNGTNTTYAAYGCNACNGTNCAYCCNAGYGCNCCNCAYTTYMGN ATHTAYGCNCAYTGY---ACNMGNAGYTTYGGNATGTAYAARAARGGNGCNATHACNYTN GCNTAYYTNAAYACNAARAAYGARACNGTNACNGTNGGNYTNAAYCARTTYTCNTCNYTN AAYGTNGAYYTNTAYATHYTNACNCCNGGNGAYACNGCNGGNYTNMGNTCNAARTTYGTN AARYTNAAYGGNGARGTNYTNAARATGTCNGGNTCNTCNYTNCCNCCNYTNACNCCNAAR CCNTCNAARGGNGAYATGGCNYTNCCNCCNYTNTCNTTYGGNTTYATHGTNGTNCCNAAY GCNAARGTNGCNYTNTGYAARAARYTNTCNGGNACNGGNGGNGAYATHAGYCARYTNTTY GGNGCNGARGAYGTNGAYTAYMGNAAYATHAAYAARACNGTNACNAGYATGYTNCCNCCN CCNCCNATGCCNTCNGCNGTNYTNYTNTCNCCNTCNATHAARAGYAGYACNCARGTNGGN TGGAGYCARTTYAARGARAARCAYCCNGAYGAYTTYGTNCARGARACNGARMGNAARMGN YTNMGNGAYGCNCARATGCARGAYGCNCARGAYACNGAYYTNMGNCARTCNTCNTCNTCN CARYTNMGNATGATGAAYGTNGTNCCNACNAAY---------CARCARCCNGTNGGNTCN AGYMGNGAYAARATHATGCARMGNGCNGARGTNGARGTNAARGARGGNMGNATGACNAAR GARGAYTAYCARGTNYTNGTNMGNCARGTNGGNGARGTNTAYAAYMGNCCNMGNGCNMGN GARGGNCCNGARGCNTCNMGNATGYTNATHCAYGAYCCNMGNATHMGNGGNAGYMGNGAY AGYMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNAARGARCAYATGGCNATHCAYTCNGGN GARAARCCNTAYAARTGYACNYTNTGYAGYAARGCNTTYYTNMGNAARYTNCARYTNGAY CARCAYATHMGNGGNCAYTAYGGNGARAARCCNTTYGTNTGYACNGTNTGYGGNAARGCN TTYGCNGCNAARAGYGTNTTYYTNGTNCAYACNMGNACNCAYTCNGGNAARAARTCNTTY CARTGYTCNATHTGYCCNAARACNTTYGTNCARAGYGGNCAYYTNACNCARCAYATGMGN ATHCAYACNGGNCARACNCCNTAYAARTGYTCNGTNTGYGCNAGYGCNTTYAARCARAAR GCNAAYYTNATHCARCAYGARMGNATHCAYACNGGNGARAARCCNTTYCARTGYCCNACN TGYGGNAARYTNTTYAAYAAYAGYAGYCARATGAAYMGNCAYYTNMGNAGYCAYACNGAY AARAARCCNTTYCARTGYGTNATGTGYTCNAARGCNTTYAARGARGGNTGYTAYYTNACN MGNCAYATGAARACNCAYGARGTNGARMGNCCNCAYGCNTGYTCNTTYTGYATHMGNMGN TTYGTNTCNAARTAYAARYTNAAYCARCAYYTNAARAARCAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNACNCCNYTNCAYATG GCNGCNTCNGARMGNGAYAAYGGNCARGTNYTNGARYTNYTNYTNCAYAAYCCNTTYATH GAYACNAAYATHGTNTCNAARGGNGGNGARACNGCNMGNCARATHTGYCAYMGNACNAGY AGYCAYTAYGARYTNTTYGARYTNATGGAYAAYAGYGTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARGARACNGTNTGGAGYTTYTAYATHGTNCAYAGYCARAGYGTNATHGAYCAR TGYAARGAYATGYTNCARTTYGCNGARAAYATHMGNATHACNGGNCCNACNTCNTAYGTN CAYYTNYTNCARGARGCNGAYYTNYTNYTNAGYTCNCAYATHGCNCARAGYAAYGTNAAR GAYTCNGARATGGAYGARTGYYTNACNMGNGTNAARMGNYTNYTNGGNGAYGTNTAYGCN CARCCNGGNGAYGARAAYTGGMGNYTNTGYCAYTCNTAYTAYAAYAGYYTNGGNATHAGY ATHGAYTAYGTNGTNAARCARGCNYTNGARCARGCNAGYCARACNAAYCCNCCNGARTTY GGNAARGGNATHYTNGAYTTYYTNGAYAARMGNYTNTTYGGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARYTNCARTCNCARYTNCAYAGYYTNAARGCNGARAAYGTNGCNYTNAARGAR GCNATHGARAARCARMGN---------------------AAYGARACNGARGCNAARYTN AAYGAYYTNGTNGCNGAYCARGARAAYATGTCN---------CAYCARGTNGGNACNYTN TCNTCNYTNTAYGGNCARAARATHGAYAAYATHACNTCNATHYTNCAYGARAARGAYYTN GAYAAYYTNGCNTCNTGYACNYTNAARTCNGCNACNTTYAAYAARCCNAAYTCNAAYGGN ATHCAYATGGARACNACNTTYAARCCNGAYAARGARGARYTNGARGAYAAYTTYGTNYTN TTYGCNTTYTGYACNTTYATHGGNATGGARGAYGTNAGYYTNGAYGTNCARAAYYTNAAR TCNGCNATHCARTAYMGNTGYMGNTGYAARTCNAARAARGGNTTYGCNTAYMGNTCNTGY ACNYTNTAYTAYTGGYTNTGYCCNMGNAARAAYMGNAGYAARAARACNYTNAARTTYGAY GGNTGYTTYCARTCNTGYTCNGARGAYGCNGTNGTNCARYTNYTNCAYGGNMGNYTNTAY GTNAAYGARGGNMGNTGGAARMGNTAYYTNGTNAGYATHCARGCNTCNGCNYTNACNGTN TGGATHCARAAYGAYCAYAARCARTGGAGYCCNGARYTNGAYTGGMGNYTNTCNGCNACN ACNCAYATHYTNCAYGTNTGYATHYTNCCNATHACNGAYAARATHGCNATHGCNGCNAGY GGNTGGGARAARACNCAYCCNATGGTNACNGTNTTYGTNTAYGAYTTYGTNAARGAYCAY ACNYTNMGNTTYAAYATHCCNTAYACNGGNTCNCARCCNCARYTNYTNYTNGTNYTNGGN ACNAGYAGYGAYAGYCAYCAYACNYTNCAYMGNGTNATGTTYCAYTCNGAYATHCAYGGN GTNGCNTCNAGYGCNTTYGAYGCNYTNTGYMGNGGNAARYTNAAYACNYTNYTNYTNTGY TAYGGNCARAAYAARGCNTGYGTNACNYTNACNTGGGAYCARMGNATHACNGTNTGGAAY ACNGARGAYAARATHGCNATHYTNACNGTNTCNATHCCNAGYTAYYTNCCNTGYYTNACN GCNYTNGTNGAYGTNMGNGCNATHAARGGNYTNYTNTTYYTNACNGCNTCNTGGMGNGTN GARGAYATGGGNGAYTGYGGNGGNATHYTNGTNTGGAAYCCNATGACNGGNTGYYTNAAR AARGCNMGNGTNTGGAAYATHCCNAAYGCNGGNTGGMGNAGYACNGARAARACNAAYAAR GTNAARAAYTAYATHTAYTCNACNAGYAGYTCNGGNTCNGTNTCNTGGTGGAAYGGNMGN AAYGGNGAYATGGTNGGNTAYMGNCARTCNAAYATHGCNACNTGYGTNCARACNTTYTTY CCNTCNCAYYTNCCNMGNGGNACNACNACNYTNTCNGTNCCNAARTCNTCNGCNYTNYTN MGNCCNGGN--------------------------------------------------- ------------------------------------------------------------ GAYGAYGCNAARGARGARATHATGAARMGNYTNCCNAARMGNYTNGTNTAYYTNATGMGN TAYGGNGCNGTNAARGARGGNATHAAYGTNGAYGAYCAYGGNTAYGCNGAYGTNACNGAR GTNATGAARGTNCCNYTNYTNAGYGTNTAYTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNCCNTAYYTNGGNAGY AARATHAGYYTNGTNTCNAARGCNGARATHMGNTAYGARGGNACNYTNTAYACNATHGAY CCNAAYGARGCNACNGTNGCNYTNGCNAARGTNMGNTCNTTYGGNACNGARGAYMGNCCN ACNGAYMGNCCNYTNCCNGCNMGNAAYGARGTNTTYGARTTYATHATHTTYMGNGGNCAY GAYATHAARGAYYTNCAYGTNTGYGARCCNCCNAARCAYTGYCAYGARAGY---GGNGTN CCNCCNGAYCCNGCNATHGTNAARTCNTCNCARCCNCCNCCNGGNCCNTCNGGNGCNGCN TTYCAY------CCNGGNCARGCNGGNTCNGGNAGYGGNCARCAYTAYCARTCN---CCN CARCCNYTNTTYTAYAAYCARGGNGGNCARCCNGCNCCNGGNTAYCCN---CCNCCNCAY CAYGGNCAYTCNGGNGGNTTYCARGARGAR---------GTNGARCARTCNCCNGARCAR ATHGTNCAYGGNTCNACNGCNGCNTTYGGNGCNMGNCCNATHTCNGGNTCNCARACNTCN ACNCCNCCNCCNAGYMGNAARTCNCCNACNTCNGAYCARGGNGTNCARGTNCARCCNMGN AGYCCNGARAARTCNAGYAAYGARAGYAGYCARCAYAARCCNCAYAGYCAYCCNAAYCAR CARAAYCAYCAYCAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYTAYCCNGCNGARGTNGAYGTNTCN TAYGAYGARTTYAARTAYGTNGARCARATHYTNCCNAARACNACNGTNCCNGARATHCCN CAYCAYTCNTCNTAYCCNACNCCNTCNGGNTGGGTNCCNCCNAAYGAYGAYATHMGNTCN CARCARCCNTAYYTNGTNMGNMGNACNAARAAYCAYGTNYTNCCNGTNTAYCCNGGNTCN MGNGARGTNTGGAARMGNATHAARCAYCAYGTNATHATHAARAAYATHGARGGNGAYATH TGGAARYTNGARTCNGARYTNMGNAARCAYYTNCARGAYACNACNGARACNGAYAARGTN ATHACNCARGTNCAYGARGTNAGYMGNTGYATHMGNATHMGNGGNGARCAYMGNGCNGAR ATHGCNCARTTYYTNYTNGAYAARGGNATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARTCNYTNATG ACNGTNTTYAAYGCNGCNAAYYTNACNTAYATGCARYTNTTYGAYMGNCAYGTNTTYTCN YTNGCNGAYATHGTNYTNAARCARAGYCAYGARACNGCNGCNGTNMGNGGNTTYAARGAR GTNGAYGAYAAYGARAAYCCNYTNTCNYTNTGYGAYMGNAARMGNAARCARGARGGNGAY ATHTTYCARGAYACNGARGGNATHGTNGAYGARAAYMGNAAYGARAARCAYATGMGNCAY GTNTAYGTNGAYAARAARTTYGGNCCNGGNAGYCARCCNACNYTNGARAARYTNGARTAY AARTTYAGYATGGGNTTYCAYAGYCARCARYTNTCNTCNAAYAAYTGYAAYACNMGNGTN AAYATHAARGGNATGTCNGTNYTNAAYGGNYTNMGNCARYTNGCNAAYAARAGYTAYATG ACNTTYCCNYTNCCNMGNCAYYTNACNGGNGTNYTNGCNGAYAARMGNAAYAGYTTYACN GTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------ACNCCN GTNATHATGYTNAARCARCARTAYMGNATGCAYCCNGARATHYTNAARYTNCCNAAYTCN TAYTTYTAYAARAAYYTNYTNATHACNGCNCCNTCNTGYATHCARTCNMGNAARTCNAAY YTNAGYCCNTAYYTNGTNTTYGAYGTNYTNGAYGGNATGGARACNTCNGGNAGYAGYGGN TCNAARTCNAAYAARAARGARGCNAARTGYGTNTCNYTNYTNTGYAARAAYGTNGTNAAY YTNYTNACNAARAARAGYACNTCNTCNGARMGN------CARAARAARATHGGNGTNATH TGYCCNTAYACNGAYCARAARAARGCNATHCARGAYAGYYTNGGNGARYTNGGNYTNTAY AAYATHYTNGTNAAYACNGTNGAYAGYTTYCARGGNCARGARAARGAYATHATHATHYTN TCNTGYGTNMGNGCNCARGGNAAYCAYCARTCNGTNGGNTTYGTNGAYGAYAGYAARMGN ATGAAYGTNGCNYTNACNMGNGCNAARYTNGCNYTNTAYATHGTNGGNCAYMGNAARACN ATGAGYACNTCNGAYYTNTGGAARYTNYTNTAYGARGAYGCNGGNAAYMGNMGNTGYYTN GTNGARGTNCCNGARACNGARATGTTYTCNGARATHGCNTCNAARMGNGTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GCN AAYAARATGMGNCCNGTNCARGCNAARAAYGTNMGNMGNGCNGCNCARYTNGAYMGNMGN AGYAAYCARAARTAYGTNGAYATGATGAARMGNMGNGGNYTNATGGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGGAYTTY GGNTCNAARTTYGTNTAYYTNGGNAAYGARCARGARGAYGARGARGARGTNAARGTNGAY GARGTNGAYGAYGTNGCNYTNTCNYTNAGYGAYTGYAGYGAYGAYGAYGGNGARACNTGY YTNYTNGAYATHYTNGAYACNGCNGGNCARGARGARTAYTCNTCNYTNAARGAYCARTAY GTNMGNGAYGGNGAYGGNTTYGTNATHATHTAYAGYATHGTNGAYGARGARAGYTTYAAR GARGCNAARGCNATHTTYMGNTGGYTNAARMGNYTNMGNGAYGTN---AAYTGYCAYGCN ATHYTNGTNGCNAAYAARCARGAYYTN------AARGAYGARGCNAARGTNAGYAGYCAR GAYGGNAARGAYYTNGCNGGNGARYTNGGNATHCCNTTYTTYGARACNTCNGCNAARGAY GGNTCNGGNGTNGTNGAYGCNATGAARGGNYTNGTNMGNATHATHCCNMGNACNGAYAGY GAYTAYAARATHGTNATGYTNGGNAGYGGNGCNGTNGGNAARTCNAGYATHACNYTNMGN TTYGTNAAYAAYGTNTTYGTNGAYGAYTAYGAYCCNACNATHGARGAYTCNTAYMGNAAR ATGATHTCNGTNGAYGGNYTNTCNGCNGTNAGYAARGAYAARMGNAARGCNTCNAARATG GCNAARMGNMGNAARAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AGYTAYAGYTCNTCNMGNGTNCARMGNGCNGCNMGNYTNAAY AAYGTNGARGCNACNAARYTNTTYYTNGAYATHMGNYTNGTNTCNATGTCNATHGAYTAY ATHCARGCNCAYAGYGGNAAYAGYCARGARGCNTGGMGNCCNCCNGCNCCNCCNACNCCN GAYGARACNGAYGAYGARAARCCNGARGGNCCNTGYTTYATGTAYGGNGARMGNATHATH AGYMGNAARGTNMGNMGNYTNACNMGNCCNATGTCNGCNATHGARMGNTCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------MGNGARYTNAARCARMGNCCN YTNGCNGCNAAYCAYTAYYTNAARTAYYTNAARGARCAYTAYGAYTTYAAYGARTAYATH GARACNYTNAGYATHYTNGGNMGNACNGARGARGCNGCNATHTTYAARTTYCARYTNGCN YTNCCNACNCCNGAYGTNACNYTNAARATHTCNAARYTNAARGAYTCNYTNMGNAGYCAY TTYAAYGCNGAYCCNACNYTNTCNTCNCAYTCNTCNYTNGTNCARGARTAYATHGAYYTN YTNGARMGNCARMGNCCNATHGARGAYTCNGAYGCNAARMGNGARGCNAGYGGNCARAGY CARYTNTTYAARGAYTTYCCNMGNAARCARTCNYTNGTNAAYATGCCNGTNATHACNACN YTNTAYTAYTGYGCNYTNTAYCAYTTYGAYYTNTCNGARAAYTCNYTNGGNAGYCCNGCN GCNATHMGNAAYMGNCAYCAYATHTCNGARAARCARTTYGTNTGGACNAGYATHGGNGCN MGNGCNAARYTNMGNCAYTGGAARGAYATHGARACNATHYTNACNACNAARGGNTGGTTY GGNGGNACNAARYTNAARGCNGTNATHGGNTTYGARAARATHGTNGGNATHYTNCAYAAR TAYAAYGCNCCNCCNGAYATHYTNGAYAARTAYYTNGCNYTNATGGAYGAYCCNGARGCN MGNYTNAAYYTNGCNAARAARATHAAYTGYCAYAARACNGTNATHGAYACNTAYGCNTCN YTNAARGAYAARCCNTCNYTNGARAAYTAYGCNTCNAARYTNGAYMGNTAYTCNGARGAR GGNCAYTAYGCNTAYAAYGTNYTNAAYGGNTCNGTNGTNAARTGGMGN---------GCN GCNGGNYTNACNACNATHATHAARGARGCNAARCCNATHACNGCNGTNGARCCNTCNCCN GTNAARCCNGCNCCNYTNGTNGTNGARAARCARAARGCNATHGTNAARCCNCARATHATH ACNCAYATHATHGARGGNTAYGTNATHCARGARGGNYTNGARCCNTTYCCNGTNCARCAR ACNTCNYTNYTNCARGARTTYGTNTGYCCNGARAARAAYCARGARATGGARAARGARTCN GARGARGAYGGNACNAGYTAYGAYGARGARCCNCCNACNYTNYTNCCNCARATGGARACN CAYYTNACNAAYCCNCARYTNAAYGAYCCNYTNCCNGAYGARCCNAARGARAGYTCN--- GCNTCNGTNACNTCNCCNTCNAARYTNYTNGARTGYGARGTNTGYCARAARGTNGGNCCN GCNTCNTCNTTYAAYAGYTCN---MGNTTYTGYTCNYTNTCNTGYTCNMGNMGNTAYAAY GTNAGYCARACNMGNMGNGTNGGNYTNTTY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYCAYACNAAYAGYTGYTGYMGNGTNAAYMGN MGNAARGAYAAYGCNGTNGTNAARCAYYTNTAYTAYAARGAYCAYGARAARTCNYTNGAR CAYTCNMGNAGYCCNYTNGTNGARYTNCCNGAYTAYACNTAYCARGAYGGNMGNGCNACN GARACNACNATHTGYCAYAARATHMGNCARGARAARAAYTAYAAYYTNGCNAARCARGTN GTNAARYTNGTNGARGARATGAARTTYGCNCARAGYCARYTNAARACNCARGARGARTCN AARGTNMGNTTYGARGARAARMGNMGNAARGCNCARYTNAARCAYAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGTCNYTNGARYTNGTNTCNAARTGYYTNGARYTNGAR------GAYYTNAGYGTNAAR GGNGARAGYTCNGGNMGNAARAAYAARAARTTYAARACNAAYAAYGCNATGGAYATHATH CCNACNAAYAARCAYGGNGTNTGGAARGARYTNMGNAARGTNMGNAARGGNCARYTNMGN GARATHAARAARAARMGNAARGCNGARATHTTYAARTCNGCNATHGARATGTAYAARGAY AARCAYGAYATHGAYCAYACNGAYAGYAAYGTNGARACNYTNYTNAARATHTCNGARYTN GGNMGNGTNGAYACNAARTAYGCNGARAARATHYTNTAYCAYCARCCNTGYMGNYTNTCN MGNGAYATHAARCCNGGNACNGARGTNTCNGARCCNACNACNGTNTTYACNGARGAYGAY TTYGARGCNTTYGCNAARGAYTAYCARCCNAAR---------ATGTCN------GTNCCN CAYACN------------CCN---CCNYTNGGNGGNGGNAAYCARCARGAYMGNCARAAY MGNAARYTNYTNYTNGARCAYATHCARGARCARAARAARMGNYTNCARCAYGGNCAYCAY TCNTCNACNGGNACNCCN---ACNCCNTCNATGAGYTCNGGNCCNGCNACNATHATHGGN AAY---CCNTCNTCNGTNCCNGGNYTNTCNGCNGCNGARTAYGCNACNATHAGYAAYCCN CARCARMGNGCNGCNYTNCARCAYGCNCAYGCNAAYTCNGTNGGNTTYTTYATHACNCAR GAYTCNTCNTTYGGNAAYYTNATHYTNCCNGTNYTNCCNMGNGTNCCNGAYACNAARACN GARGCNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TTYGTNAAY ATGGCNAARCARTAYAAYTAYGTNGCNGGNGTNGGNTTYGAYAARCCNAAYATGACNGTN AAYGCNCAYCCNGARAARAARYTNTGGGARATGGGNGTNATHAGYTTYCAYMGNAARATH GAYTAYTCNTGYAAYTTYTGGYTNGARYTNAARACNYTNGAYATHCARACNGGNATHAAR TAYGGNGCNCCNATHAGYTTYTTYYTNAAYTAYGTNTCNATHCCNAARAARGGNYTNAAY ATGACNGTNYTNGTNGCNAAYAARACNACNACNMGNYTNCCNGARTCNGTNTCNYTNAAY TTYACNCCNAARAAYGTNAARMGNAARTGGYTNATGACNAARATGGAYCARGAYATHGAY CCNTGYACNGTNGTNYTNAAYGGNAGYCARTAYGTNCAYGCNGTNGAYTCNACNGTNAAR YTNACNGAYAAYAGYAARAARGGNYTNGTNATHTCNGCNCARGAYTCNCCNGTNATHYTN TGGGGNACNGCNYTNCAYACNCCNTCNCCNTTYCCNGTNCCNYTNCARCCNTTYAAYTGY TCNACNYTNACNTCNGTNGCNTTYAAYYTNTAYAAYAAYATHTGGAAYACNAAYTAYATH TTYTGGTAYCCNTAYAGYAAYGAYGAYGCNAGYTTYAARTCNMGNTTYAGYYTNTAYTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARGARAAR MGNAARAARGARAARGCNGARMGNYTNGARCARGARMGNAARGCNAARGARGARGCNGAY MGNAARGCNAARGARGARGCNGARMGNATHGARAARGARAARCARGARMGNGCNAARAAR GARGARGARGARMGNYTNCARMGNAARAARAARYTNGARATGATHATGAARMGNGTNAAR ACNGAY------------------CCNGCNCARGAY------------------AARGTN GAYAGYCCNGTNAARTCNTCNGGNAGYTCNCCNAAYMGNAGYGCNYTNGCN--------- ---TCNCCNGARGTNCARGARATGCCNCCNTTYACNCARGARAGYGAYAAYTCNTCNGGN TCNGARGAYGGNAARCARAAYGAYGCN--------------------------------- ---------------------------CCNGCNCCNAGYGCNTCNGARAAYGCNGARAAY TCNGTNATHTCNTCNTCNTCNTCNTCNGARCCNGCNGCNYTNACN--------------- ------------CCNGTNGTNMGNAGYGCNTCNTCNGGNGAYATHATHGAYAGYGCN--- GCNGAYGARGAYAARAARGARATGGARAARGGNGAY---------AGYYTNGGNACNYTN AAYACNCCNGTNAARTCNTCNACNAGYGGNACNACNTCNGARCCNTCNTCNACNGARGTN AARTCNMGNTTYAARTCNCCNYTNYTNCARCARYTNGTNGARAAYAARGGNGGNTCNGAY TCNCCNAGYGGNTCNCCNAARTTYAARTCNCCNYTNYTNCARAAYYTNYTNGGNAARACN AARGTNGGNGCNMGNATGGGNYTNTCNGCNAGYATGGGNGAYYTNAAYYTNAAYAARGAY AAYAAYACNAAYGCNGCNAGYAGYACNACNCARCARCARCARCARAGYTCNAGYCCNYTN TCNYTNAGYCCNTCNGGNTCNAGYAARGARATHTCNAARGCNGGNCARGAYGARGAYAAR GAYGTNGAYGARTCNATHGGNTCNTCNGCNTCNTCN------ACNTCNGGNAAYGAYCAR GARTCNTTYAARGCNCARTCNTCNCAYGAYGARGAYCAYYTNACNAAYGGNAARTCNTCN GGNGAYGARTCNGGNGGNMGNAARTTYTCNCCNATGGGNATGATHGAYTCNGCNYTNGGN TCNAGYATHGARCCNCARCARGGNGAYGTNYTNGARTTYGCNGCNCCNAGYTCNGTNATG TCNAAYGGNCAYGGNGCNAARAAYAARCARGAYYTNATGGARGAYTCNAGYATHAGYGTN CARACNCCNGARGARACNGTNACNGCNCCNACNGCNACNACNTTYAAYGGNCARTCNTCN TCNCARGAYGARACNGARGARGARGGNGGNAGYGGNCAYTTYGARGARYTNATHGAYYTN CCNTAYTCNACNAGYAAYAGYTCNAARTCNGCNGTN------TCNCCNATHATHGCNTTY GARGARAAYAGYYTNMGNACNGCNGAYGTNGGNGARTCNATGTCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATHAAYTCNAAYGGNCARGTNYTNGARTCNCARTCNCCNTGGMGN YTNTCNTTYATHACNGAYGCNATHTGGGGNATHATHAAYTTYATHGTNYTNTTYTTYCAR ACNATGTTYAAYCCNAAYAARAAYAGYMGNGGNGAYAAYTAYACNTCNGAYTAYMGNAAR CCNGGNGGNGGNGGNCCNCCNACNMGNMGNATGGGNGGNTTYMGNGGNGGNMGNGGNGGN ---GTNTTYTTYAARAARGGNCARGCNACNATHATGTGYTCNAARTGYGARAGYAGYAAR AAYCCNGGNTGYGARATHCARCCNCCNGCNCCNGCNACNTGYGTNTCNTCNGGNAGYGGN ATHCCNCARTCNTGYTCNGTNGTNMGNGTNTAYAARAARGAYACNGGNGTNGAYCARTTY ATHMGNAGYTGYTCNATHTCNCARGARGAYMGNTGYTTYGAYAGYAARCCNGGNTAYMGN ACNTGYGCNATHATHTGYTAYACNAAYGGNTGYAAYTCNGCNCCNGAYATGTTYGGNGAY GGNYTNGGNAARAARAGYYTNATGCCNGARATHAGYCARGCNTTYACNGCNGTNAARAAY MGNYTNGAYTCNTCNYTNTCNAAYGAYGARGAYTCNCARMGNTAYYTNTTYGARGARGCN MGNGTNAGYGCNGCNACNATHYTNYTNCARYTNAGYMGNATHATHTAYTTYTTYGAYAAY ATHTGYAAYCAYATHCCNAARTCNYTNGARTAYCARYTNYTNTCNAGYTAYACNGARYTN ACNGTNGAYGTNCARGTNGTNCCNMGNGARTGGCARACNGCNTCNATGAARGARGCNTAY YTNMGNMGNATHACNGARGTNCARAGYGAYGARGARCCNGARAARGTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNMGNGTNMGNAARAARGTNGARGCNYTN MGNTCNYTNGARAAYGGNGGNACNYTNTCNCCNAGYYTNAGYGARGAYTAYYTNGAYGCN TTYAGYGAYTTYMGNCCNMGNGCNAGYTCNAAYGCNAGYAGYTGYGGNMGNYTNTCNCCN ATHCAYGCNGTNGCNGARCCNGAYYTNCAYGAYAAYCARGTNCCNCCNATGTCNCCNAGY ATHTGGAAYGCNGAYATGAAYCARTCNCCNACNYTNTAYCCNGGNGAYTGYTAYTCNGAY YTNGTNGAYTCNYTNGGNGAYGGNATGAARYTNTCNTCNCCNGAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TAYTTYATGYTNYTNCARGGNACNTGGTTYTGG CARATHTCNTTYATHYTNTGGAARCCNTTYGGNYTNCCNTGGAAYCAYGAYAAYGCNGGN GAYYTNACNYTNGCNTGYYTNTTYTTYGCNTGGCAYTGYGGNGGNAAYYTNYTNYTNGTN GTNTCNGGNGCNGTNACNTTYGTNTAYMGNGGNAARGGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TAYGAYGTNAAY ACNAGYGTNYTNGTNACNGAYTTYCCNCCNTGYACNATGGARAGYCARYTNMGNGCNGTN TTYMGNGAYTAYMGNGTNATGGAYATHTGYGTNYTNAAYAAYGGNTAYTCNAAYGGNMGN ACNMGNGCNYTNYTNTAYATGAGYACNATHTAYGARGCNATHAGYGCNGTNACNGAYGAR ATGGGNTAYGTNATGGARGGNMGNCCNYTNAARGTN------------------------ ------------------------------------------------------------ ---------------------------------------------------AAYAARACN GTNCCNATHAARCARYTNGARATHMGNCARMGNGARGCNGGNYTNAAYACNACNATHTCN CARAAYAGYAARGGNTTYGCNYTNYTNCARAARATGGGNTAYAARCCNGGNACNGGNATH GGNAARTCNGGNGARGGNMGNGTNGARCCNGTNAGYTTYCARGTNAARACNGGNMGNTCN GGNYTNGGNAARGAYTCNGAYATGAARMGNAARTCNTCNGARATGAAYAGYATGMGN--- ---------GCNGCNATGCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYGGNTGYGAYGTNATHCAYYTNAAYCAYTGYGAR CAYGTNTTYCAYAARYTNTGYGTNGTNCARATGTAYTCNMGNGGNAARAAYGGNTAYYTN CARTGYCCNACNTGYAAYMGNGTNTAYGGNGARAARGTNGGNAAYTGYCCNGCNGGNTCN ATGGTNTGGAAYCAYMGNMGNGAYGTNGARYTNTCNGGNCAYGARGGNTAYGGNGCNYTN GARGTNGTNTAYAAYATHGTNAARGGNMGNCARGCNGARGGNCAYCCNAAYCCNGGNAAY AGYTTYAAYGCNMGNGGNTTYCCNMGNAARGCNTAYYTNCCNGAY--------------- ---------------ACNGAYGARMGNMGNMGNYTNATGTTYACNGTNGGNACNTCNGCN ACNACNGGNGARTCNGAYACNGTNATHTGGAAYGAYATHCAYCAYAARACNGARTCNAGY GGNAAYCAYGGNCAYGGNTAYCCNGAYCCNAAYTAYYTNGAYAAYGTNMGNGGNGARYTN GCNGCNCARGGNGTNACNCARGARTCNYTNATHGAR---------------------GAY MGNATGGARAARACNTAYMGNATGGARACNTGYMGNTGYYTNTTYTCNGCNGCNAAYGTN TAYACNAARTCNAARYTNGCNAGYAARGARCARGTNGARAARGCNGTNTCNAAYYTNAAR AAYYTNACNAARGTNTTYAARYTNACNGAYACNGAYGAYACNAAYTTYGTNGARAARTCN GARYTNMGNYTNYTNTTYAARATHYTNGARTAYGCNGTNAGYGAYAAYYTNYTNCAYAGY ATHATGACNMGNTAYGGNGGNMGNMGNCARMGNYTNGGNYTNGARGAYTTYGTNCAR--- ------------------------------------------------------------ ---------------------------------------------GARGGNTTYCARACN CARGAYAARGAYGTNCAYGARTCNTTYACNTCNYTNMGNCCNAGYGCNAGYGARYTNAGY ATHGAYACNGAYTTYACNGCNCARTGYTAYMGNTGYGARTTYTAYGGNAARGARCAYTTY AAYTAYTAYGGNYTNGAYGARAGYYTNGGNCCNATHGTNATHTCNATHAARYTNGARGCN GTNCCNTCNGARAGYGTNAAYGTNATHGTNMGNACNAARTTY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGAYCAYCAYTAYGGNGTNGCNGTN ACNAAYAARTTYGCNYTNTTYACNGAYGAYGAYGARGAYCCNATHGARGCNGTN------ ---------YTNAARATHAAYGCNCARAARGAYGARGAYAARAARGCNAARGCNAARAAR ACNYTNGARGARGARGAYMGNAARGCNGAYAARCCNGCNGCNCCNCARAAYGAYGAYGCN GARCARAAR---------GARGTNGGNGAYAARCARTGGCARACNGARAARGGNAARGGN AGYGCNMGNAAYMGNGARCCNMGNGARYTNMGNGARAAYGAYGGNGAYMGNMGNCCNCCN MGNMGNCARGGNCCNMGNGARTTYAARGAYGGNAARGCNCCNMGNGAYTAYAARGAYGGN AARCCNCCNMGNGAYTAYAARGAYGGNAARGCNGGNGAYGARAAYGTNCCNCCNGARTTY MGNGARCARCCNCARGGN---GGNTTYAARMGNMGNGARGAYMGN------GARGGNAGY GGNTTYGGNGGNGARMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNGGNMGNGGN GGNGARMGNACNAGYGGNAGYGGNTTYGGNCCNMGN------------------GGNGAY CARAARMGNGARTTYGAYMGNCAYAGYGGNACNGAYMGNACNGGNATHAARGCNATHGAR AARAARGARGGNCAYGGNGCNCAYAAYTGGGGNAGYTTYMGNGAYGAYATHGARGARCAR GGNCARGCNGCN---------GCNCCNGARGAR---AGYAAYGARMGNGARAGYCARCCN GARAARACNGARYTNAAYGARAGYGTNGARGGNGGNAAYGTNGCNGARGARGAYGCNCAR CCNCARCARATGACNYTNGAYGARTGGAARGCNYTNCAR---GTNCARAAYAARCCNAAR CCNAARTTYAARATHMGNCARGCNGGNGARGGNGTNGAYTCNGGNCARTGGAARCARGGN GTNGARTAYCARAARAAR---YTNGTNGCNGAYCARGAYCAYGGNGARCAYGARAGYGAY CAYAGYGAYCAYCCNGGNMGNGAY---------AAYAARCARYTNYTNTCNGAYATHMGN ATHACNTTYAAYGAYAAYCCNMGNMGNGGNMGNGGNMGN---MGNGGNGGNMGNGGNGGN ATGGARMGNGGNGGNGGN---------------MGNGGNMGNGGNAGYMGN------GGN GCNGCNMGNGGNTTYGGNAAYAAR---AARGARGCNGCNCCNMGNTTY---GAYGARGCN GAYTTYCCNTCNYTNYTNAARACNGCNGCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNCAYGTNMGNCAYAARGGNAGYMGN---MGNATHMGNGAYGTNAARYTNAAY GTNGAYAARAAYAARAARTTY---ACNAARAARGARAARAARAARTCNCARCCN---YTN AGYAGYAAYYTNATHGARAARTCNACNATHATHGCNGARAARCCNGTNGAYAAYGTNTGG GTNMGNAARTTYTAYCCNACNCCNMGNTTYTCNATHAAYACNGCNYTNGARMGNCAYCAR GCNTTYGCNCARCCNGCNATGYTNGAYAAYATGGAYGGNYTNGTNTAYYTNGAYATGACN YTNGAYTAYTCNTCNAARAARAARACNAARTTYATGAARAAYTTYMGNTCNACNYTNYTN YTNCCNCAYCCNTTYAAYTGGGGNAARCCNCCNACNATHYTNGTNTTYTGYAARGARGAR GARCAYACNAGYYTNGCNATGTCNYTNGGNGCNMGNCAYGCNGGNGTNCCNGCNCARGTN GTNAARYTNATHGARAGYGGNGTNYTNCAYCCNAARGAYTTYACNCAYGTNYTNGCNACN GTNGAYTGYACNAAYGARATGTCNCCNGCNMGNTCNTAYTTYMGNGAYAARTTYCCNCAR AARGCNAARGGNACNYTNGGNACNGAYYTNAAYGCNATGTGGAAYYTNTTYTAYAAYGGN TAYACNTAYGARACNCARAGYYTNTCNGARTCNCARGGNMGNYTNCARGTNCCNATHGGN CARYTNAARCARCCNACNAGYCAYATHATHGCNAAYTTYGARGCNTTYATHGAYTCNATH TGYAARCAYMGNAGYGTNGCNYTNGGNCCNTTYATHCARTCNATGACNGTNGTNGCNCCN CCNTCNCCNGARGARTTYATHGTNAARGTNGARGAYTAYGTNCCNGGNTAYAARAAYGAR GARGTNGAYTCNGAYGAYGARGAY------------------------------------ ------------CCNCCNCCNGGNACNYTNTAYCARGTNCARGCNACNCAYMGNTAYACN GGNGARGAYGTNGAYGARYTNAAYTTYGARCCNGGNGARATHATHTAYGTNATHAARTTY GARAAYCCNGARGARCARGAYGAYGGNTGGCARATGGGNATHAARCARTGYGAYGGNTTY AARGGNGTNTTYCCNGARAAYTTYACNMGNAARATG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARACNCAYGCNATHTCNGAYTCNGARGGNTCNGAYGGNTCNGAYGAYYTNTTYGGNGAR GAYAGYGAYGAYGAYGAYGTNGTNMGNTCNAARGTNAARGGNTCNAARGARTAYGAYGAY GARTAYGAYGTNGAYACNGAYGTNGAYGARCCNGGNGARGTNAARAARGARGARMGNAAR CCNYTNTGYAARTAYGGNAGYAARTGYTAYMGNAARAGYCCNTCNCAYYTNCARGARTTY TTYCAYCCNMGNAAYAARMGNAARACNGARGARCAYGGNATGGCNGCNTCNCCNTCNAAR AARYTNAARAGYTAYCCNGAYAARACNMGNCCNAAYGTNTTYGARGAYTTYGARCCNTTY GGNTTYTTYYTNACNAARGTNTCNGGNATHCCNCCNCARTTYAAYACNGTNGGNGCNATG AGYYTNAARGAYATHYTNTCNCCNGARATGGGNMGNYTNAARMGNTCNTGYCAYTTYAAY TTYATGTTYGAYGTNCCNTGGYTNGTNCARCARTAYTCNCAYACNGAYMGNTCNYTNCCN ATHATGYTNGTNCAYGGNGAYCARGGNMGNGCNGARYTNGAYYTNAARCAYGARGCNTCN CCNTAYCCNAAYATHTCNYTNTGYMGNGCNMGNYTNGAYATHCCNTAYGGNACNCAYCAY ACNAARATGATGTTYYTNYTNTAYGARACNGGNYTNMGNGTNATHGTNCAYACNGCNAAY YTNATHCCNAAYGAYTGGCAYCARAARACNCARGGNGTNTGGATHAGYCCNACNTTYCCN MGNYTNAARAGYCCN---TCNGAYCCNGGNGARTCNTGYACNAARTTYAARGCNAAYYTN YTNCARTAYGTNTCNGCNTAYAARTCNCCNMGNYTNTCNCCNTGGGARGCNATHATHTCN GAYCAYGAYYTNTCNTCNGCNACNGTNCAYATHGTNGCNTCNGTNCCNGGNMGNCAYACN ATGAAYGAYAARCAYCAYTGGGGNCAYYTNAARYTNAARAARATHYTNTCNGCNMGNGGN CCNGAYCARGGNYTNGTNAARAAYTGGCCNGTNATHGGNCARTTYTCNAGYATHGGNTCN YTNGGNGCNAAYCARGAYGCNTGGYTNYTNAGYGARTGGGGNCARTCNYTNTGGACNTGY ATHAARTCNYTNCCNTCNCCNATHCCNCCNTCNAARYTNCAYYTNATGTTYCCNTCNAAR GAYAAYATHMGNYTNAGYYTNGARGGNTAYAAYGGNGGNGGNTGYGTNCCNTAYTCNATH AARACNGCNTCNAARCARCCNTGGYTNACNCCNTTYTTYTGYCARTGGAARTCNGARGGN MGNGGNMGNTCNMGNGCNGTNCCNCAYATHAARACNTAYGCNMGNTCNTCNCCNGAYGGN TCNGARGCNGCNTGGTTYYTNGTNACNAGYGCNAAYYTNTCNAARGCNGCNTGGGGNGCN TCNGARAARAARGGNAGYCARYTNATGATHMGNTCNTAYGARATGGGNGTNYTNTTYYTN CCNGGNGAYTTYGGNTGYAARAAYTCNTTYAARGTNACNAGYCARATHGAYAARYTNCCN AAYCCNGARGTNAARACNTTYCCNYTNCCNTAYGAYYTNCCNACNACNACNTAYATHAAR GGN---AARAARTCNGTNGARYTNTTYTAYGAYGTNGTNTCNCCNTAYTCNTGGTTYGGN TTYGARGTNATGATGMGNTAYCARAAYMGNTGGAAYATHAAYYTNAARYTNMGNCCNTTY TTYYTNGGNGGNGTNATGCARTCNTCNGGNAAYAARCCNCCNGGNYTNGTNCCNAAYAAR GGNATGTAYAGYATGYTNGAYGTNGAYMGNTGYGCNMGNTAYTTYGAYGTNCCNYTNGTN ATHCCNAARAAYCCNTCNGARYTNATGTTYGARAARGGNTCNYTNAARGCNCARMGNTTY YTNACNGCNGTNGAYATGAARTGYCCNGAYAARGTNGARGCNGTNTCNMGNGARTTYTGG ATGMGNGGNTGGTGYMGNGAYGARGAYYTNTCNGARGAYGCNAGYYTNGCNGARGCNGCN CARAARGCNGGNYTNAGYCARCARGAYATHCARGAYTTYYTNYTNMGNGTNAARGAYCAR GAYGTNAARGAYMGNYTNAARAARACNACNGAYGARGCNATGGAYYTNGGNGCNTTYGGN TCNCCNATGATHGTNGCNGARGTNAAYGGNAARAARGARTGGGTNTTYGGNAGYGAYMGN TTYCCNATHYTNGCNCARATHYTNGGN--------------------------------- ------------------------------------------------------------ ---------------------------TGGYTNAARGGNGCNMGNACNGTNYTNTGYATH GGNGCNGCNATHYTNGCNAARAGYGCNATHGGNGCNACNYTNAAYYTNGTNGTNGTNAGY MGNGGNGAYMGNCARMGNTAYYTNCCNTTYATHATHTGYGCNTTYTGYTGYGGNGGNGGN TTYYTNACNTTYGTNGGNGAYATGATHATHGCNGCNAAYTTYMGNTCNYTNAARGAYYTN CCNAAYGGNGGNTCNTTYTCNGARGGNGCNAARGARYTNATHGGNGAYACNTTYTCNYTN GGNTGGGGNTTYGGNYTNGAYATHTTYTCNGCNYTNYTNGCNTGYGTNGCNGGNGGNTTY CAYTTYYTNGCN------------------------------------GCNACNAAYATH GCNMGNGTNGTNGCNGTNACNACNGTNATHYTNGGNTTYYTNTAYMGNGGNGCNATHCAR ATHTAYATHGAYACNYTNTGGGTNTAYYTNCARCARGAYACNYTNTTYCARTCNGCNCAY TAYGARACNATHTAYGTNACNGTNATHTAYACNATHYTNATGATHATHTAYCCNTAYGCN ATGCAYCAYATHCCNTTYTTYCARCARTTYMGNATHTCNAARGARGTNAARTAYGTNAAY CARACNGTNATHGGNACN------GAYYTNYTNTTYCAYYTNAGYCCNYTNYTNATHGCN TAYATGYTNATHATHAARMGNTAYTCNGGNGTNCCNTAYTCNGARATHGCNATHMGNAAR CARGAYTGGATHGTNMGNACNMGNCCNYTNCCNMGNGAYTCNCCNGARTTYGTNACNATG TGYYTNCAYGTNTCNGGNAGYGTNYTNYTNTTYGAYGCNTTYTTYACNATHGTNCAYTAY GCNATGCAYMGNAAYMGNTTYYTNTAYAARTAYTTYCAYTCNCARCAYCAYGAYCAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AARMGN CCNGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYGAYYTNTTYYTN------------------ CARAGYTCNGTNCCNGGNATHGTNCCNGCNTAYAARMGNATHGCNATGGGNGAY---GCN TCNAARGGNGGNATHCCNYTNTAYCCNGCNAAYCAYYTNATHTCNCCNTAYCARCARCAR GCNGCNTCNYTNATGCCNYTNCARCARCAYCCNTCNTAYATHCCNATGCCNTAY------ ---------------------------------------------------TGYATHGAY YTNACNGTNGAYATHGGNGGNGAYGARGTNATHGAYYTNACNCAYAGYACNAAYATHATG GAYTCNCCNGTNGTNGTNATHAGYGCNGCNGAYGAYGTNGGNCCNGTNMGNMGNCARMGN GGNAGYGGNMGNMGNGGNMGNMGNMGNTCNTTYTCNMGNGGNYTNACNTCNCARGTNGCN GTNTCNCCNTCNTCNTCNCAYACNCCNACNTCNTCNTCNTCNAAYGTNGGNMGNYTN--- ---GARYTNGARAGYTGYGAYGAYGARYTNCCNGAYATHCCNTTYGARATHCCNAARGAR AGYTCNAARGCNAAYGCNATHTTYTGYAARTCNCCNACNATHCARATHCARTGYCCNGTN TGYYTNGAYGAYYTNAARCARATHAARTCNAGYAARAARMGNGTNATGTCNACNATHTGY GGNCAYATHTTYTGYGARGARTGYATHGTNAGYGCNATH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TGYTCNTCNTGYAGYACNTTYGCNMGNAAYGARGARYTN ACNMGNCAYCARMGNATHCAYTCNGGNTAYAARCCNCAYCARTGYCARGTNTGYTGYAAR AARTTYGGNMGNAARGAYCAYYTNAAYAARCAYGTNAARACNCAYYTNCARTCNTCNGAR AARAARGTNCAYYTNTGYGAYYTNCCNAAYTGYGGNCARACNTAYACNMGNTCNGAYGCN YTNGCNMGNCAYCARATGAAYTCNCAYGGNTTYAARGCNAARCCNTCNAARTGGMGNCCN CAR------TGYGGNATGCCNYTNTAYCAYTCN--------------------------- ------------------GTNATGGGNGAYGGNAARTGG---------TTYTAYGAYAGY AAYTAYCCNGARTAYYTN------------------------------------------ ---------------------ATHACNTAYCARMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYMGNAARACNTTYCARGARATHGARMGNGAR ATHGTNCAYCCNYTNTAYCARATHCARGGNGTNTGYGARAAYGARAARCARMGNAAYYTN AARCARACNGTNAARAARGCNACNTCNGARATGYTNGGNTAYYTNAARCCNGAYGTNGAY YTNCARMGNGTNMGNCAYAARGARTGGGARGGNAARGTNYTNACNMGNGARCARGGNYTN TTYTAYGGNYTNATHAGYYTNATHCCNATGAGYGTNGAYMGNYTNACNACNATHGAYTAY AGYGTNGAYGARTAYGTNAAYGAYTTYCCNGARATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AGYGARGARGAR CCN---GCNGTNCAYAGYGAYGAYGARCCNYTNATHCAYCAYCCNTTYAARGTNAARGAY ACNTCNACNAAYATHGTNATGAAYATHMGNAAYGCNAARCARYTNCCNGTNYTNACNCCN TCNGARAARCARGCNCARCARGCNTCNYTNMGNYTNGCNTTYCCNGTNTCNAGYGGNACN CAYCAYMGNGCNAGYGARTCNGARTGGGTNCCNGTNGARAARACNACNGCNCCNGTNACN ACNACNTCNAGYAARCCNGTNGAYTCNAARMGNGCNTCNGARTCNCAR------------ ---CCNGARCCNAARAAYAGYATHTTYCCNACNGCNCCNTCNACNGTNGAYATHGGNGCN ATHATHTCNGARMGNYTNCARGCNGTNMGNAARYTNCARGCNAAYCCNTAYGAYGTNCAR GCNYTNAGYTCNATGCAYAARGCNCARGARAARGCNAGYCARTGGGCNCARTCNAARCAY YTNCCNGGNCARTTYGTNGGNAGYACNGGNGCNCARGTNATGTCNCARCARGARYTNATG GGNGAYAARMGNMGNCARGCNTGGGTNAARAARTCNCARTTYAGYACNGCNACNCCNGTN AGYGGNGGNATHGGNATGTTYYTNYTNCARAARATGGGNTGGAARCARGGNGARGGNYTN GGNAARAAYAAYGARGGNAAYACNCARCCNYTNCARYTNGAYATHAARATHGAYMGNAAR GGNYTNCARAGYGCNGCNGAYAAYCCNAARTCNMGNCCNCARATHGCNCAYGTNCCNCAR GCNAARGAYYTNTCNCAY------------------AARCAYCCNGTNTCNGCNYTNATG GARYTNTGYAAYAARMGNMGNTGGGGNCCNCCNAAYTTYACNGTNGTNCARGARGAYGGN CCNGCNCAYAARAARTGYTTYYTNTTYAARGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGNCCNGTN YTNTTYGARATHTAYGGNYTNATHATHTCNGGNCCNGTNGAYACNTCNTCNGGNGGNGGN AARGARTTYTAYGTNMGNGAYCARTCNGCNACNACNMGNTGYATHTTYTAYGARATHGTN MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNGTNGTNCARGCNGARGARYTNGGNTGY GARGGNAARGTNGARGARGCNCARGGNGTNATGAARYTNGTNGAYCARYTNAARGARGAR MGNCAYCARYTNGARATGAARCCN---GCNATGCARGAYGAYGGNGGNCCNYTNATGAAR CARATGGARGTNTGYGAYGTNTGYGGNGCNTTYYTNATHGTNGGNGAYGCNCCNCARMGN CARGAYGARCAYYTNATGGGNAARCARCAYGCNGGNTAYGCNCARGTNMGNGCNGARATH GAYMGNMGNAARAARAARGTNMGNGAYGARACNGARGCNMGNGARGCNAAYGARAAYMGN YTNMGNYTNGARMGNGARGARMGNGARAARGARMGNCARMGNGARMGNGARGARMGNMGN ---MGNGARMGNGAYGTNGAYMGNMGNMGNGAYMGNGAYMGNGAYMGNMGNMGNAARAGY MGNTCNMGNAGYMGNGAYMGNGGNAARGAYMGNMGNMGNTCNMGNAGYMGNGAYAARMGN MGNCARMGNAGYTCNAGYMGNGAYMGNMGNAAYAARMGNAGYMGNAGYMGNAAYMGNGAR ------------------AGYTCNAGYMGNGGNAARMGNTCNMGNMGNTCNTCNAGYMGN GAYMGNAARMGNGAYMGNMGNCAYTCNMGNGAYAARAARTCN------------MGNAGY MGNTCNMGNGAYMGNAARGAYMGNAGYMGNGAYMGNGAYYTNGARMGNAAYGGNGGNAGY ACNAGYAGYMGNGARGARATHAGYMGNGAYAARACNGGNGGNTTYGGNCARTGYATHGCN GAYGAYACNMGNGTNATHGAYTGYCCNAARAARYTNATHGAYTTYATHTCNGAYCAYTTY AAYGGNGARMGNGGNAARAAYTGGGARGAYYTNYTNGAYYTNTAYCARTGGAAYTAYAAY GARATHATGYTNTTYMGNAAYAARAAYCAYCCNCARGGNTAYTTYTGYAGYATHYTNAAR GARAGYCARTTYCARGAYTAYACNATHGARYTNYTNAARGARGAYYTNGCNAAYYTNCCN AARAARGAYTCNYTNGCNGAYATHGARAARTGGATHGAYGAYTAYAAYATGGAYTTYGAY TCNTCNTCNAARTTYATHGCNTCNYTNGCNMGNTTYYTNCARTCNYTNTGYAAYGGNTAY GTNGARTTYGAYAARGGNGTNGARGTNATHGGNCAYATHTAYYTNAGYGTNGAYAGYGAY ACNGGNMGNAARATHGAYTAYGTNYTNAAYGARAARGTNTGYAARAAYGAYAAYTCNGTN ACNTTYATHAGYAAYAGYTTYCAYGCNCARCCNGCNGARAARCCNCARCCNACNCCNAAR AARCCNGARGGNGAYAGYAARAARGAYGAYTCNGAR------GARGAYAGYGGNCARTCN ATHCCNAAYAGYACNAAYGTNGGNACNATGGGNGCNYTNMGNGAYAGYTCN--------- ------------------AAYAARMGNCCNMGNTCNCCNYTNCARMGNMGNATGGGNATG GGNMGNGGNTCNGGNGGNCCNGCNGCNAARTCNCCNMGNTAYCARGAYCARTCNGGNGCN TCNGCNCARTCNTAYAAYACNGAYGGNYTNTCNACNAAYAAY---AGYAGYGGNGARCAY TAYGAYAGYTCNTAY---------CARGGNGGNGAYGARGAYAAYTAYAGYCARGAYTAY ------------------TCNAAYTCNGAYYTNGAYCARAARCCNGTNATHGARCCNGAY ATHAGYATHGTNAARGARGARTAYATGGCNAAYCARCARCCNGGNGCNTCNTAY---CCN AAYATHCARTCNTCNGGNCCNGGNMGNGGN------------------------------ ---------MGNCARTCNTCNTCNCARCARCCNTCNTAYCCNTCNAGYTTYTCNTCNAGY AGYGAYTAYACNGGNTCNTCNATHGARCCNMGNGAYCCNTCNGARYTNACNMGNGCNCAR CARGARGARYTNGARATGTAYTAYMGNAARGGNACNGAYCARCAYYTNACNTTYYTNMGN AAYATGMGNGARGCNCAYGCNATGTAYCCNTTYACNGGNAARMGNGAYAARGARYTNTTY GAYAARGCNYTNGCNGARYTN--------------------------------------- ------------------------------------------------------------ MGNYTNTTYGCNTGYTAYAAYGAYGGNATHATHAAYYTNYTNGARAARTAYTTYGAYATG AAYAARAARCARTGYAARGAYGCNYTNGAYYTNTAYAARMGNTTYYTNGTNMGNATGGAY AARGTNTCNGARTTYYTNAARGTNGCNGARAAYATGGGNATHGAYAARGGNGAYATHCCN GAYYTNGCNAARGCNCCNGCNAGYYTNYTNGAYGCNYTNGARCARCAYYTNGCNTCNYTN GARGGNAARAARTCNACNACNCCNACNGGNTCNAGYAARCCNTCNGGNTTYACNACNGCN YTNAAYAAYATGTCNAGYAAYACNTTYAAYGTNAGYGARGCNGARAARAARMGNATHYTN GARGARGARAAYCARCARYTNCARMGNCAYAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY ATHYTNGTNGARAAYCARGGNMGNGTNGGNTTYTCNACNGAYATHAAYTTYAAYGCNAAR GGNYTNATHGCNAAYGTNACNYTNGGNGGNGARATHYTNAGYGAYTGGYTNATHTAYCCN YTNCAYACNAGYAARYTNAAYGARTCNGTNTGGCARAARTAYMGNCAYAARTCNCCNCCN CARAARCCNGTNACNTCNCCNGARGGNCARTGGTCNACNCCNTCNTTYTAYGTNGGNGAY YTNATHMGNGCNTCNACNCARGARTTYGARGAYACNTAYYTNGAYCCNMGNCCNTTYATH AARGGNCARGCNTTYATGAAYTCNTTYAAYYTNGGNMGNTAYTGGCCNACNMGNGGNCCN CARGTNMGNYTNTAYATHCCNAARCCNGTNTTYYTNGCNCCNCCNGTNGCNAAYMGNYTN TTYYTNTTYGARYTNGARGGNTCNCCNTGYTCNTCNCCNTCNGAYTGYAARGTNTCNYTN GTNGAYACNCCNYTNYTNGAYGGNCCNAAYGGNTCNGAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNATHGCNTGYGTNGTNTGYMGNCARTTYGAY GTNAGYTCNGGNAAYCARYTNGTNGARTGYCARGARTGYCAYAGYYTNTAYCAYCARGAR TGYCAYAARCCNACNGTNACNGGNCARGAYGTNAGYGAYCCNMGNTTYGTNTGGTAYTGY TCNMGNTGYACNAARAGYTTYAARAARATGATGGCNCARAARCCNGTNAAR---CCNAGY AARCCNACNYTNCCNYTNACNTCNGCNGTNAARGARCCNGCNTCNATHATHATGAARACN ACNAARCCNGARAGYGAYGCNGGNATHCARGCNTTYMGNMGNATGGAYCCNAARGCNATH GTNCCNCCNAARGAYGCNGCNAGYYTNACNTCNTCNTCNAARGCNATGGTNGGNYTNGCN GGNYTNGCNGCNAAYYTNACNAARCCNMGNGGNGAYTCNAARACNGCNTCNTCNAGYTCN AARAARGARCAYAARGGNGAYTCNAGYAARTCNTCNGARACNAARTCNCARCARGGNYTN AARCARGARAGYTCNAAYTCNTCNGGN---------------AARCAYTCNTCNTCNTCN TCNTCNACNAARAGYGARTCNMGNAARTCNGARTCNAGYAARTCNTCNTCNTCN------ ---------------------TCNTCNTCNTCNTCNTCNAAYAARGAYGARTCNMGNGAR YTNAARMGNTCNGAYTCNAARAGYAGYAARTCNGAYGARGAYAARMGNGARAARTCNGAY TCNTCNAARTCNTCNTCNAARGAYGAYTCNAARAARTCNGARAARTCNTCNTCNCCNAAR CAYTCNGTNTCNTCNAAYAAYAAYTCNCCNCCNCCNACNCCNGCNTCNCCNTCNGGNAAR AGYAGYAGYAGYAGYGGNGGNAGYAGYAGYAAYAAYAARCARGCNGTNGCNAAYYTNTCN ATGGTNACNGCNAAYAARMGNATHCARATGATGAARAARAARGCNCARACNAAYCCNAAR GARAARMGNGTNCAYATHAAR--------------------------------------- ------------------------------------------------------------ ------------------CCNAARATHACNYTNGCNCCNAGYGAYCAYMGNGTNCCNGAR GAYGARACNGTNAGYTTYTTYTGYMGNGCNTCNGGNATHCCNACNCCNACNTTYACNTGG GARMGNGAYGGNMGNMGNATHAARGCNAGYMGNCAYMGNATHGARATHCAYGAYACNCCN TAYATHTCNGCNYTNMGNATHMGNGARGCNAARGCNYTNMGNGAYAAYGCNACNTTYACN TGYYTNGCNACNAAYGAYYTNAAYCAYGTNATHATHGCNGGNCCNGAYACNGCNAAYAAR ACNTCNTTYGTNTTYCARGCNTCNGTNACNGCNGCNACNAAYGGNTTYAARGTNGTNCAY GTNTGYACNCAYCCNYTNTCNAARYTNCCNACNYTNGTNCAYGGNATGCCNACNCCNGAR CCNTCNGTNATGAARAAYGTNGAYTTYYTNTAYTTYGARGARGCNACNGAYGTNATHGCN TAYTTYGCNAGYATHCAYATGAARAARAAYYTNCCNAGYTAYATHATHGTNGARGAYATH YTNTCNTAYGCNTCNCARAARYTNGAYAARTCNGTNGARMGNACNYTNGCNAARYTNYTN GCNYTNATHTCNAAYGCNAGYGCNTGGACNGCNAARAAYAAYGAYACNGGNAARTGYAGY GTNYTNYTNACNGCNCCNGCNMGNATHAARTCNATGCARAAYGTNYTNMGNCARTTYGAY TAYGARGTNGCNATHTAYGARGGNCCNACNAARGAYGCNATGCARTCNAARYTNTCNTTY ACNGGNAAYAARGCNCAYGTNTCNYTNACNTTYCAYMGNCARAAYAARTGYYTNATHYTN GAYGAYGTNTGYGTNACNGTNAARGARAAYGTNAAYAARGARYTNATHCARATHAARACN GCNGAYGARCARGARATGCARMGNMGNATHGAYTCNTTYATHMGNAAYAARMGNAAYGAR GTNGAYGARMGNAAYATHMGNGARTTYATHTCNCCNTTYGGNTCNGAYCCNAAYAAYAGY TGYGCNMGNGTNGARGCNATHTAYGTNCAYMGNGARGGNATGAARAGYCAYATHAAYYTN AARAAYGTNGARAAYTCNTAYGGNCCNCARACNMGNYTNMGNCARGAYGAYCARGAYMGN MGNYTNTAYTGGATGATGCCNGCNGAYGTNCARMGNGCNGARGCNGTNGAYGARMGNYTN TCNAAYATGGARCAYCAYYTNAAYATHTCNGAYAAYGARGGNGAYATHTTYMGNMGNATH AARGCNYTNGARGARMGNATHAGYTTYYTNGARGGNYTNTCNCCNGARTAYTTYACNAAY GGNATHCCNCCNAGYAARCAYTGYAARACNAARCAYACNGARMGNGAR------------ ------------------------------------------------------------ ---------GAYCAYYTNTTYATHATHGTNACNCARTAYCARAARYTNGGNACNGTNATH GARGTNTCNMGNGAYGTNGTNAGYGAYGARGTNCARGGNCAYATHCCNATGTTYTCNACN AAYGTNYTNYTNGGNAARGAYGARCCNYTNACNCAYGTNATGGCNAARACNATHGTNACN GCNYTNAAYCCNCCNATHCCNGTNATHYTNACNYTNGCNYTNAARGARACNTCNCAYGAY TCNGTNCARGCNATHATHCARYTNATHAARTCNTGYYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GCNGGN TAYAARGTNCCNCAYAARACNYTNATHTCNYTNATHTTYMGNTTYGCNGAYGARAARGGN CARATHAGYYTNGAYAGYTTYYTNTCNYTNATGGCNMGNYTNATGAARACNTTYAAYACN TTYCAYCAYTCNCARAARGARGGNATHGCNACNTTYTCNYTNGAYCARTGGYTNGAYAAR TGYYTNTTYGGNAGYGTNATGACNTCNTGYGAYACNGAYYTNGCNTCNGCNYTNMGNGGN YTNYTNGGNGARGAYYTNTCNTAYTAYCARATHGTNGGNCCNGGNGAYTGGGTNACNTGG TCNACNAARGCNGGNCARYTNMGNGGNAARCARYTNACNYTNCARCAYATGATGCCNAAR TTYTAYGARGAYATHGARGARCARCCNACNMGNMGNAARYTNGCNTGYGARGGNATHMGN GAYGAYYTNYTNGAYTGYYTNYTNAARAGYGAYTGYTGYAARATHGARAARAARACNCCN MGNGARTGYATG---------AGYMGNGTNGGNGAYCCNTCNGTNCCNAAYGARTGYCAY AARYTNMGNGTNGCNTTYTTYGAYTGYMGNMGNTCNATGYTNGAYATGMGNACNMGNTTY MGNGGNMGNAARGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARGAYMGNTCNMGNAARAAYGCNATHCARGCNAARATHAAYMGNGARNNNAARAARGCN TAYATHAARAGYYTNGARCARGARATHTCNTCNYTNMGNGCNGAYAAYACNAARYTNAAR TCNGARAAYAARMGNATGCARAGYAAYATGTCNGAYYTNGARGARGARGTNGARTAYYTN AARTCNGTNYTNGTNAAYTCNAGYTCNYTNTCNGGNYTNYTNAARAAYATHTCNAAYGTN AARGARGTNAARYTNTCNGCNACNGTNYTNGGNMGNAARMGNTCNATGGCN------GAR GAYCAYAGYTAYAAYTTYGTNGCNTCNGCNCCNGARAARMGNGCNMGNMGNATHAAYGAR AAYYTNAARAARGCNGGNGTNTGYYTNCAYGTNAAYGGNGGNTCNGCNTGYYTNGARTTY TGYGCNCAYTGYTCNAARYTNGCNCAYAARACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY GARCAYGGNYTNGTNAAYCAYATHCAYYTNATGTGYGAYMGNCAYYTNGAYCARYTNATH ATGTGYTCNYTNTAYYTNATHGCNAARGTNACNGAYAARACNYTNACNTTYCARAAYATH ATGAARTGYTAYMGNYTNCARCCNCARGCNCARAGYCAYGTNTAYMGNAGYGTNYTNYTN CARGAYMGNCAYMGNCAYAGYTCNGGNAGYAGYGAYAGYAGYAARAGYAAYAGYAGYACN YTNCCNACNACNTTYGGNGGNCAYATHGAYCAYAGYAAYCCNGGNGGNACNAGYTAYGGN GTNAAYGCNGGNCAYACNTGGTCNCAYGGNGGNGGNAGYAARACNACNGTNACNGGNGGN TTYGAYCAYAAYTCNCAYACNGGNAAYAGYTTYGGNTTYGGNGTNTCNCAYACNTTYGGN AARMGNCAYGTNGAYAAYAARGTNTTYGTNGCNGTNCAYGCNGGNGCNGGNAAYCAYTCN AARGCNAAYGARAAYTAYAAYAARAAYATHTGYAARACNGCNTGYATGCARGCNATGGAR YTNYTNAARTCNAARMGNTCNGCNATGGAYGCNGCNACNGCNGCNGTNGTNGTNYTNGAR GAYGAYGARAGYACNAAYGCNGGNTTYGGNTCNAAYYTNAAYGTNTAYGGNGAYGCNGAR TGYGARGCNTGYGTNATGGAYGGNTCNTCNYTNTAYTTYGGNGGNGTNGGNGCNYTNTCN GGNGTNAARAAYCCNGTNAARGTNGCNAAYYTNYTNGTNAARGARCARATGGARGGNCCN YTNCCNTTYGGNMGNGTNMGNCCNAGYATHYTNGTNGGNAARGGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYAARTCNATHCAYGTNATH CARCARGARGAYAARGAYGGNAAYACNAAYAARTTYATHTTYGTNYTNGGNTTYAARAAY ATGGAYGARGARGCNGCNGARCARGAYMGNCARYTNGCNATGGARGAYAAYTAYGCNTTY GTNTAY---------------GTNMGNGTNTTYYTNAGYGTNGCNACNGGNGCNYTNTTY GGNATHGCNYTNGARAARGGNMGNGTNTTYGARCCNCARGTNATHMGNGAYCARATGYTN TTYMGNMGNTTYGGNATGATGAARATGTTYYTNTCNGCNTCNGCNGTNGGNATHYTNTGY TTYTCNTTYYTNCAYGGNATGCCNCAYACNATGMGNAARATGGGNYTNGCNYTNCARAAR TTYCCNGARAARCCNCCNACNAARTCNYTNYTNGGNGTNGTNYTNGGNGCNGTNATHYTN GGNAGYGGNATGACNATHGCNGGNGCNTGYCCNGGNACNGTNYTNGTNCARYTNGCNACN GGNGTNGARAAYGCNTGGATHACNYTNGTNGGNGGNYTNTTYGGNTCNATHGTNTAYGCN ACNTCNCARGCNGAYYTNCCN------ATHTTYYTNAARTCNAGYTCNCARCCNAARAAY YTNGAYAARTAYYTNAAYGTNCCNTAYTCNTCNATHGCNGTNCCNYTNTCNTGYGTNYTN GCNGGNGTNGTNTTYGTNYTNGARTGGTAYTCNCCNTGGTAYGARGARGTNGAYCCNTCN YTNYTNACNGARGGNYTNATGMGNGCNGGNGCNTGGCCNCCNTTYATHGCNGGNYTNGTN ATHGGNTCNYTNCARATHCCNACNGTNYTNGTNAAYGARGAYACNYTNGGNTCNTCNAGY GCNTAYGTNACNATHATGTCN---------ACNATHTGGCCNTCNATHAAYTTYAAYAAY GARGARAGYTAYYTNAARMGNTTYMGNAAYGGNYTNGAYAAYTGGTGGCARGTNATHCAY GTNGTNGCNGCNGTNTTYGGNGGNGCNYTNTCNGCNACNGCNTCNAAYACNATGGGNACN GTNCCNGGNYTNCCNTGGTAYCAYGCNTTYTCNGGNGGNTTYYTNATGYTNTAYGGNGCN MGNYTNGCNGGNGGNTGYACNAGYGGNCAYGGNYTNTCNGGNTTYGGNYTNTTYTCNYTN ATHTCNYTNGCNGCNGTNCCNGCNATGTTYGGNGGNGGNATHGCNACNGCNTTYTTYATG AARCAYGTNYTNAAYATHGARATG------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CARATGACNTCNACNCAYYTNCARYTNGARGAYCARTGY AARACNYTNTCNGAYAAYMGNGARGTNATHCARTCNGARYTNATHAARYTNGARGARGAR AAYGAYAGYYTNGTNGAYAARTAYTCNAARACNGCNCARCARYTNCARAAYGARGAYATH AAYYTNCCNAAYAAYYTNGARGARATGCARYTNYTNYTNYTNAARTAYMGNGARGARATH ATHTCNGCNAARGTNGCNAARGARCAYACNGARGARACNYTNAARAGYCARATGGCNTTY YTNAARTCNCARGTNYTNGGNGARCARCARGARAARGCNACNYTNGARGARACNYTNTCN CARGARATHTCNAGYYTNCARTCNAARYTNTCNGARYTNGARTCNACNAARCARGAYYTN GARCARGARTCNTCNAARMGNTCNGARGCNGARTCNAARYTNAARGARTCNGAYTCNGCN YTNAARGGNYTNCARGCNAARTCNAARCARYTNATHGGNAARYTNCARGARMGNYTNGAR GARGARGAYAARMGNMGNAGYAARYTNGARTCNGAYAAYCAYCAYYTNAARGGNAARGTN CARTCNYTNCARGTNGAYYTNGAYAAYAGYGARGCNGTNCARMGNGAYTTYGTNAARYTN TCNCARTCNYTNCARATHCARYTNGARAARATHMGNCARGCNGARACNGARGTNMGNTGG CARCAYGARGAYGAYATHGAYGAYTGYAGYAAYTGYAARCARCCNTTYTCNGTNACNAAR MGNAARGTNAGYTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNGARTAYMGNGGNMGNGGN---MGNAGY AGYAGYTGGMGNGGNGGNCCNCCNMGNGGNGGNGGNTTYMGNGGNGGNMGNGGNGGNGGN GGNGGNGAYMGNGARGGNGGNGGNMGNGGNGGNTTYMGNGGNMGNGGNGGNTTYTCNMGN GGNMGNGGNGGNCCNCCNMGNAGYMGNGAYGAYYTNTCNCCNCCNMGN------ATGTCN MGNAGYTAYGAYACNACNGAYMGNGGNMGNGGNCCNCCNCCNAGYMGNMGNCCNGAYMGN TAYGAYGAYAGYTTYGAYMGNGGN---CCNTCNATGMGNATGAARGAYATGTAYTCNTCN CCNCCNMGNGARTCNGGNMGNAGYTTYGAYMGNCAYTCNCCNCCN------CCNMGNMGN GAYMGNGAYTAYCCNCCN---MGNCAYAGYGAYCAYATGAGYTCNMGN---GAYTAYYTN CCNCCNMGNAGYTAYAGYCCNCCNMGNGAYTCNGGNTAY---AGYTCNTAYAARGAYTCN TAYAGYTCNGGNCCNMGNGARGAYMGNMGNCCNGCNMGNGAYTAYGCNCCNCCNMGNGGN ACNGGNGAYTAYGAYMGNGGNGGN---AGYAGYMGNGAYTTYMGNGGNGGNCCNMGNGGN GAYTAY------AGYTCNMGNGAYTAYCCNCCNCCNTCN---MGNAAYGGNGARTTYMGN GAYTCNATGAGYAGYMGNGAYTTYMGNGAYGCNCCN---------MGNGGNGGNGAYMGN TAYGGNAGYGGNGGNMGNGGNAGYAGYAGYMGN--------------------------- ---------------GGNMGNTCNMGNTTY------------GAYGAYAGYMGNGGNCCN CCNCCNMGNGARTAYAGYTCNMGNGGN---------------MGNGGNGAYMGNGAYGAY GAYMGNGGNAGYMGN------GGNTTYATGAAYGGN------------------------ ------------------------------------------------------------ ---------------------------------------------------------TCN ATHYTNGARACNAGYATHGGNAARGAYGCNGAYTGYGARMGNGTNTTYAARMGNTTYACN TAYAARTGYYTNCARATHATHGTNCARTCNMGNATHGARMGNCCNGTNYTNCARGGNAAR GAYACNTCNAAYGAYTAYTTYAGYATHAAYYTNCCNGAYAGYGGNTCNATHGAYGARCAR ATHAARTAYACNYTNGARGGNATHAARTCNTTYCCNGTNAARGAYMGNTCNATHTGYGTN GARATHGCNYTNMGNACNAAYGAYGGNGAYCAYATGTTYYTNGARACNTGGGAYATHAGY TTYAAYYTNAGYAGYYTNGAYATGTCNGCNAGYAARGTNCARCAYATHTTYACNMGNATG GGNYTNACNYTNAARTCNYTNYTNTCNGCNACNMGNGCNACNCCNGCNTTYMGNYTNGCN AARAAYCARGGNGARAARGGNGGNGGNTAYAARYTNAAYTAYMGNTTYTAYYTNGGNCCN CCNAARACNCAYATGYTNGGNGARGAYTTYAARACNATGMGNGCNGGNGCNGTNCCNTCN GCNTTYGGNYTNYTNAGYATHGGNGTNTCNTAYMGNACNAARYTNYTNYTNTCNCCNGAY ACNACNGCNTCNTCNTCNAGYGTNATGCARGTNACNGAYAAYTAYTTYATGAARGARAAY MGNGCNCAYTCNACNGGNCARGTNTAYTCNGAYCCNAARCCNTGYTAYTCNTCNGTNAAR MGNAARCCNTCNYTNTCN------------------AGYCCNGARAAYATGGCNGCNGCN CCNTAYAAYTAYACNATHTCNCCNTCNTCNCARGGNACNGAYGARGAY---ATHGCNTCN AARYTNTCNGCNGGNAAYAAYGCNATHCCNTGGCCNYTNGCNAGYATHYTNAAYATHGAY GARYTNCCNGARCCNGCNGTNGGNGCNTTYTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNGTNCCNYTN GCNGCNTCNATHCCNATGATHAARGAYATHATHTCNGTNTTYTTYMGNAARYTNGTNTCN YTNYTNGAYGARGGNAARGTNYTNCARAAYACNGARYTNTCNAARAGYTTYYTNGARTGY YTNAARAGYTTYTGGTCNYTNTGYTCNMGNCARCARAAYATHGTNACNTCNTCNCARTCN TTYGGNAARTGGCAYCCNMGNYTNYTNGARGARATHACNCCNYTNGCNTCNGTNTTYACN GAYYTNTTYATHTCNGCNTAYGGNCAYAARGARGAYCAYGAYYTN------TGGTCNMGN MGNYTNTAYAGYTGGYTNAAYTTYGAYYTNCCNGAYMGNGCNATHAARGTNGCNYTNYTN GARGCNGARGGNCAYGAYAARGAYGGNGCNGARYTNGTNGGNCCNYTNYTNMGNCARGTN YTNCARMGNAARTTYGAYAGYTCNTCNAAYCCNGARTAYYTNYTNCAYTTYYTNYTNYTN AARAARTGGCARGGNYTNTCNGCN---YTNTCNGAYGTNAARGARGTNTCNAARTTYYTN AARGCNCCNACNTCNTTYYTNGCNTGGYTNAARACNTAYTGGACNTCNGGNGCNAARTAY ATHCCNGARGAYACNYTNYTNGARGGNGCNGARGTNAGYMGNTTYYTNYTNCARYTNAAR ACNGARAAYGTNYTNGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GTNATHGARYTNTCNAARATHTGGCARYTNTCNGAYYTNAAYTGYGAY GGNGCNYTNTCNATGGARGARTTYTGYATHGCNATGCAYYTNGTNGTNYTNMGNMGNAAY GARATHGARYTNCCNGAYMGNYTNCCNYTNGAYGAYGGNAARCCNGTNATHGARAARGAY GARMGNGGNATGCCNGTNTTYAARGTNMGNTTYAAYATGAARGAYTAYMGNCCNGARGAR GTNAAYGTNAARATGGAYAGYAAYAARATHGTNGTNTCNGCNMGNCAYGARGARAARAGY AGYGGNTCNACNGTNAGYMGNGARTAYAAYMGNGARGTNAAYGTNCCNGTNGARGTNGAY CCNYTNGCNYTNCARTGYYTNTTYCARCCNGAYGGNTTYYTNGTNTTYAGYGCNCCNYTN CCNGCNCCNAARTAYGAYGCNATHAARGAYGCNTCNGGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNTGGCARACNTCNTCNACNAAYCARGARGAYGGNGGNGAYTGYGAYAGYACNCCN ACNACNCCNTCNGAYAAYACNCCNTCNGCNAGYTCNACNTGGAAYAAYTGGCCNAAYCCN CCNGGNTCNAAYAARGTNGAYTCNYTNMGNCCNCAYACNATHAGYTCNGCNTAYGARAAR GGNCAYGGNMGNCCNGCNYTNAARCCNGAYYTNTTYGARCCNCCNTCNGGNGGNGTN--- ---------------------------------------GARTTYACNGAYGAYGARATH MGNCAYGARYTNGCNCARYTNGGNTAYTAYGAYGTNCCNCARGAYAARYTNGARGAYTTY AARAARGAYYTNATGGCNYTNATHTCNAARGARMGNAGYAARTCNACNTCNYTNAAYAGY AGY---------------CAYGCNTCNGAR---ACNGGNMGNGAYGTNAARGCNMGNCAR GARGGNCARTTYCARACNGARGAYTTYACNAGYTAYGGNCARCCNTGGACNGGNCAYTCN MGNYTNAAYGARGAYTGGCAYTAY---GGNGGNGARAGYGGNCCNAGYCCNMGN------ ---------------------------------CCNAARACNGCNCCNGCNGGNMGNGAY TGGGAYTTYYTNAAYAARGAY--------------------------------------- ---------------TAYGAYGARMGNAAYCARAGYTGYAAYMGNGAYGAYGTNTCNGAR ACNAAYTCNGARACNMGNTTYATGAARMGNAARACNTCNMGNAARACNCCNAAYGGNTGY MGNYTNGTNGAYGARTCNTTYACNGAYACNGAYTCNGGNGTNTTYGARATHTAYGARAAR ATHAARAGYYTNGCNATGMGNGARTGYGARTGYGGNAARACNMGNACNAARTCNGGNGAY GTNGARCCNCCNTAYMGNATHAARGGNAARACNAAYAARTAYCCNTCNGTNATHMGNAAR YTNGARCCNCCNCAYACNMGNAAYYTNGTNAARACNGAYGTNAAYGARMGNCAYAAYATG TAYAARGARGCNTGGMGNACNCARCCNGCNATHGGNGAYGAYCAYMGNATHGCNYTNMGN AARGCNATGCAYAGYMGNYTNATGAARCAYGARGARGTNAARATGAARCCNAARGTNTAY ATHCCNAAYYTNTAYGTNCCNCCNCAYGARAARYTNMGNAARGAYGTNMGNTGGAARGTN MGNGARGCNTTYGARAARTAYGARYTNCCNGCNCAYGGNTTYTAYCAYGARAGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GTNAARTCNATHGTNGARGARGCNYTNGTN CARTTYAGYGCNGAYMGNGTNGGNATGCCNGAYTTYGCNYTNGARTCNGCNGGNGGNAGY GTNYTNAGYGTNMGNTGYTCNGARACNTAYTAYMGNAARACNGCNYTNGTNAGYGTNTTY GGNGTNCCNYTNTAYTAYACNTCNAAYTCNCCNMGNACNGTNATHCARCCNAAYGTNCAY CCNGGNGARTGYTGGGCNTTYAARGGNGAYTAYGGNTTYGTNGTNATHCARYTNTCNCAR CCNATHCARCCNAAYGGNTTYACNYTNGARCAYATHCCNAARAGYYTNGCNCCNTCNGGN ACNATHGAYAGYGCNCCNAARGCNTTYACNGTNYTNGGNYTNAARGCNGARGAYGAYYTN GARGGNATHAAYYTNGGNAAYTTYACNTAYYTNGAYAAYGGNAARCCNATHCARCAYTTY TCNGTNCARAAYCARCAYCCNGGNGTNTTYCARTAYATHGARYTNMGNGTNATGAGYAAY CAYGGNAAYCCNGARTAYACNTGYATHTAYMGNTTYMGNGTNCAYGGNYTN--------- ---GARTAYCARTGYCCNTCNMGNYTNACNCAYMGNYTNTCNCARYTNGTNATHGTNGAY AARCARACNAAYAARTCNGAYTAYCAYYTNCCNYTNGCNAAYACNGTNATHACNTCNTTY ATHGAYCCNCARMGNYTNAAYGARATHTCNGARATHAARGAYCCNTCNTCNCAR------ ------CAYACNCCNGCNAARGARGCNAARGARATHATGMGNATHMGNCAYMGNAARATG AARAARCAYAARYTNAARAARYTNMGNAARMGNATGTAYTTYGTNTGGMGNAARGARAAR YTNACNMGNAARGCNAARMGNGAYGCNATHTAYTGGAARGARGTNTCNGAYATHAARAAR GAYGGNGAYGAYTTYAAYGCNGARACNTTYGTNAARGGNCARYTNGARAARGCNMGNMGN GGNGGNTAYTGYATHAAYGTNTTYGAYTCNAARGTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARATHATHACN GCNYTNAARTCNTCNATHYTNYTNYTNGTNGTNAGYTGYGTNTAYCAYTGYATHGCNGTN YTNTTYGGNGCNCCNGTNTTYACNTTYGTNTCNGARACNTAYCAYTTYGCNATHYTNATG ACNGTNYTNACNGGNYTNCCNATGTGYGCNGTNGCNGGNCCNMGNYTNGAYAARTGGATG GAYATHTTYACNACNGAR---MGNGARCCNGGNYTNCARACNGTNGTNTAYYTNACNACN ATHGGNGCNYTNYTNGGNGCNTGGATGGGNGCNATHCCNATHCCNYTNGAYTGGGAYMGN CCNTGGCARAAYTGGCCNATHAGYTGYTCNGTNGGNTGYGTNTCNGGNTAYTCN------ ------------------------------------------------------------ ------------CCNGGNAAYCCNGGNGTNCCNACNTTYTAYAARGAYTTYATGMGNGAR YTNTAYGARCARTCNGAYGGNCARATHCCNGTNTGGGCNGTNAGYCAYGCNGGNCAYTCN MGNCCNCCNGAYGARACNYTNTCNTTYAGYGAYGTNTTYGCNACNAAYGAYAARAARTAY GGNYTNGARGCNCARATHGAYCAYAARGCNACNTTYATHAARGAYTAYATHCCNTCNGAY GTNAARGTNATHYTNATHGGNCAYTCNATHGGNTGYTAYTTYATHYTNAAYGCNYTNGAY AARATHCCNGTNCAYCAYGTNCARMGNTGYTTYYTNYTNTTYCCNACNATHGARMGNATG GCNGTNTCNCCNAAYGGNYTNACNYTNACNCCNGTNTTYMGNTAYYTNMGNTGGATHATH GTNTTYTTYACNTTYTTYTGYATHYTNYTNCCNGTNACNYTNMGNGARAARATHGTNCAR TTYATHTAYMGNAARATHGAYTAYCCNCCNTGYGTNGTNMGNTCNATHYTNTCNACNGTN ACNCCNTGGCCNACNAAYTTYTCNACNTTYYTNGCNAARACNGAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARAGYTAYGAYYTNYTNTCNMGNTAYCARTGGATHCAY GAYTTYCARGTNACNGAYATHYTNAARAAYGGNATHYTNCAYAARATHCCNCCNCAYTGG TAYGCNTGYYTNTCNCARYTNACNATHGARGARYTNAAYGARGTNCCNTTYYTNGGNGAR AGYAGYATHTCNAARTAYCCNGARTGGCCNTGYTCNTTYYTNCARGARTCNAGYCARYTN GCNAAYYTNMGNAAYGAYAARYTNAAYGCNGCNGARGTNAARACNGTNGARATHAAYTCN GARATGGCNMGNGGNATGAARAGYAARAARYTNCAYGARGTNACNMGNATGGCNTCNYTN GTNCARGARATHATHACNGARACNAAYTGYAAYGTNGTNATHGAYGTNGGNTCNGGNYTN GGNTAYYTNGAYCAYGTNYTNCAYCARAARTAYGGNATHAARGTNYTNGGNYTNGARACN GTNCARAGYCAYGCNTCNGCNGCNGARMGNMGNGCNGTNAARCARGGNATHACNTGYGAY GGNATHMGNACNYTNCARTGYCAYYTNGARGAYAARGARGARTCNTAYAARGCNTTYATH AGYCAYGTNGARTCNGTNTTYCCNACNYTNAARTGYGAYTGYTCNTCNMGNGAYACNGAR GARATG------------------------------------------------------ ------------------------------------------------------------ ------------------------------AGYCCNGARAARTTYGARAARTTYCCNYTN AGYGAYYTNGGNCARMGNATHTGYTCNCARATHTCNCARGARAAYGGNAAYGTNTTYATH ACNCCNTTYACNYTNMGNYTNGGNGCNCARGARACNMGNTGYMGNTGGCAYCARCARACN AARAAYGAYCAYGARAAYCAYATHAARCAYGTNGCNTTYMGNGGNYTNYTNAGYYTNACN GAYGARGAYGAYGGNCAYATHMGNCARAARGTNMGNCAYTGYAAYTTYGARTCNATHCAR AAYTTYGTNGAYTCNTTYTAYGGNYTNCCNTCNGARGAYYTNGCNATHACNGARAARMGN AAYYTNYTNYTNTCNYTNTAYGAYCARAAYAARAARGAYTTYGAYGCNATHGARATHYTN ACNYTNYTNCARGTNATHYTNCARCCNGTNATHGARACNYTNGTNTAYGARGAYMGNGCN CARTGGYTNMGNGARCARGGNCAYATGAAYGTNAARGTNYTNCCNGTNTTYGAYGARYTN ATHTCNCCNMGNAAYYTNGCNYTNGTNGCNYTNAAR------------------------ ------------------------------------YTNTTYTCNGARAARTTYAGYGAY GGNGTNAARYTNGCNGCNAARAAYGTNTGYMGNCARYTNGAYATHYTNTCNGARYTNTTY TCNMGNCARTGYAAYGTNATHGTNGCNCARMGNATHMGNMGNTCNTAYCARATHYTNATG YTNTAYMGNAAYYTNTAYGGNGARTGYYTNYTNAARGARAARGTNMGNTCNCARTTYACN MGNYTNAARMGNAARCCNYTNATHACNYTNYTNTCNGCNGCNGTNTTYAGYTGGGAYGCN GARMGNGTNTCNGAYGARGARATHAARMGNTGYCAYCARGARATHAAYGARGTNAAYCAR YTNGTNAARAAYAGY---AARTTYTAYAARGAYAAYCCNGAYYTNGCN------------ ---------------------------CCNAARAAYCCNGTNTGGGARCARATHGTNGAY AGYAAYGAYTTYAARGTNTGGMGNCARCARYTNCCNAAYTCNCARYTNTAYAARTAYMGN GTNYTNGGNCAYTTYAARGAYATHCCNGCNMGNGCNTTYTAYAAYACNCARGTNGAYGTN CAYTAYTGGAARGAYTGGGAYGCNCARACNATHGAYGTNMGNATHGTNGAYMGNGAYAGY AARACNGGNTCNGARGTNATHCAYTGGYTNTAYAARTTYCCNTAYCCNATGTAYCCNMGN GARTAYGTNTAYGTNMGNMGNTGYACNATHTAYCCNGARAARAAYGCNATGATHATHACN GCNMGNGCNACNCARCAYCCNAARTGYCCNATHAARAAYAAYAAYGTNMGNATHGARACN TAYTCNTCNCARATGGTNATHACNCCNTAYACNTTYTTYGAYGARGAYGGNTTYTCNTAY GTNATGTCNTAYTGYGAYGAYCCNCARACNAAYTTYCCNCCNACNTGGTAYAAYTGGGTN GCNAGYTCNGGNGTNCAYGARTTYYTNCARMGNATGCAYMGNGCNGCNATGAARAARCAY GARAARACNACNGTNGAYTAYGCNTCNAAYMGNATHGARAGYGGNCCNTCNAAYYTNTAY CCNGGNATGGTNCAYATGYTNYTNMGNYTNAARGARGTNGTNCARTGGACNMGNATGACN GCNYTNGARYTNATGYTNCAYYTNATHTCNGTNYTNATHTTYTCNYTNYTNGTNGCNATG AARGTNGARGGNGAYATHAAYGTNTCNTGGCCNGTNATHTTYTCNCCNYTNTTYATHTGY GAYGGNYTNAAYGCNTAYYTNTGYGTNATHATHTTYGTNMGNCARTAYMGNGARTAYGAR YTNAARCARGCNTGYYTNMGNYTNTCNAAYTCNYTNTCNGTNATHGCNYTNATHTTYACN TTYAARYTNYTNYTNTGYCARAARYTNGARAAYGGNGGNYTNAGYTGYTCNGARGTNTTY GCNCCNATHTTYGTNYTNTCNCARGTNTTYATGTTYMGNGCNTGYMGNATGCAYGAYCCN GARTCNYTNACNGARYTNCCNGARGTNGCNAARACNAARGARGCNCARCARYTNGTNGGN ATHYTNCCNTAYGARGAYGAYGARGAYGARTCNGARTTYMGNCCNGTNTGGGAYAARGAR AGYTGGGCNAGYGCNYTNGARGARTTYAARATHAAYYTNACNGTN--------------- ---------------------------------GTNAARGARGARGARGAYYTNTTYTCN GAYGCNAARGARAARCCNTCNTCNCCNGAYACNGTNAGYCCNCAR------TCNGTNAAY GGNACNGAYGARAAYCCNTTYGGNAGYGAYGARAARGARGAYGAYGAYYTNTTYAARGGN GGNAGYTCNGARATHAARYTNGARTCNGAYGAYGARGAYGTNTCNGAYGTNAAYAAYAGY GARTCN------------------------------------GCNCARCCNGARGARCCN GCNATGGCNGCNTCNTCNAAYAARGARGTNACNCCNGARATHTCNGTNTCNGARGTNATH ACNGCNAARACNAARATHGCNGCNCCNTCNYTNAARTCNGAYGARYTNTCN---GARGAY AAYGAYGARAARGARCARTAYGARYTNGAYATHAARATHACNGARAAYYTNAARATHGGN GAYGGNATGTCNGCNTAYATGGTNTTYAARATHGTNTCNAARACNGCNAAYCCNGCNTTY MGNCARCCNGARAAYGCNGTNYTNMGNMGNTTYAGYGAYTTYYTNGGNYTNTAYTCNAAR YTNGCNATGAARCAYGTNCCNYTNGGNATHATHGTNCCNCCNGCNCCNGARAARAGYGTN ATHGGNATGACNAARGTNAARATGTCNAARGARGAYACNGGNTCNATHGAYTTYATHGAR MGNMGNAARGCNGCNYTNGARMGNTAYYTNATHMGNACNGCNGCNCAYCCNGTNYTNGCN GCNGAYTCNGAYTTYATHGARTTYYTNGARAARGAYGGNGAYYTNCCNAARGCNACNAGY ACNTCNGCNYTNAGYGGNGCNGGNGTNATGMGNYTNTTYCAYAARGTNGGNGARTCNATH GARAARATHACNYTNAARGTNGAYGARAGYGAYGARTGGTTYGARGARAARCAYCARCAR ATHGARGCNYTNGAYCARCARYTNAARAARYTNCAYTCNAGYYTNGARACNYTNGCNGCN CAYMGNMGNGARYTNTCNGGNAGYACNGCNGTNTTYGCNAARAGYGCNGCNATGYTNGGN AAYGTNGARGARCAYACNGCNYTNTCNMGNGCNYTNTCNCARYTNGCNGARACNGARGAR AARATHGARATHGTNCAYAARGAYCARGCNGARGTNGAYTTYTTYACNATGTCNGARYTN ATGAARGAYTAYGTNGCNYTNATGGGNGCNGTNAARGGNGTNTTYCAYGARMGNATHAAR ACNTAYAARCARTGGAARGAYGCNGARACNATGYTNGGNAARAARMGNGARAAYAARGCN AARYTNGARATGCARGGNAARGCNGAYAARYTNTCNCARGCNMGNACNGARATHACNGAR TGGGARCAYAARGTNGARAARGGNCARGARGAYTTYGARAARATHTCNAARAAYATHMGN AARGARGTNGTNMGNTTYGARAARYTNMGNGTNTCNGAYTTYAARACNAAYGTNATHAAR TAYYTNGARGTNYTNATGGARAAYCARGARAARYTNATHAARTAYTGGGARACNTTYYTN CCNGARGCNAARGCNATHGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AARCCNAARCAR GTNYTNATHAGYAGYMGNACNTAYCARAAYTTYGARAARYTNYTNGTNGAYYTNAGYACN ATHGTNGARACNTCNACNGGNGTNAARTTYATHTTYTCNTGGCCNGAYGGNAARGARATG AAYTCNATHACNCARTTYGARAGYGGNAARTAYTAYATHTGYTCNAGYACNAARAARYTN AARTGYCCNTAYGARGGNTGYAAYAARACNTTYCCNTTYCCNACNGTNYTNMGNMGNCAY ATGAARGTNCAYCARGGNTAYGARTGYGAYATHGARGGNTGYGGNGARGTNTTYGARACN TAYYTNAARYTNMGNAARCAYAARGCNGTNGARCAYGGNCCNGAYYTNGTNTGYMGNCAR TGYCARACNCCNTTYAARTCNMGNCARACNYTNGTNCARCAYYTNAARACNCAYYTNTTY GTNAARGARGTNTTYGTNTGYACNGARGTNGGNTGYGARMGNACNTTYYTNTAYAARAAR AAYYTNAARCARCAYATHMGNGCNTAYCAYYTNGGNGARAARGTNTTY---ACNMGNAAR AARATHCCNAARGAYGGNGARCARGCNCARAARATHCCNGCNCCNMGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AAYCCNAARGTN ATGGGNAGYCCNYTNAAYCARAARAARGCNTTYYTNACNAARAARGGNYTNACNCARGAR GARATHAAYYTNGCNATHGARMGNGCNGGNGTNACNGARACNAGYACNGCNCCNAGYAAY GTNAAYCARGCNMGNGCNCCNCCNCCNGGNTAYCARCCNGGNATGATGACN--------- ------CCNTAYGGNCARATGCAYCCNCCNATHCCNCCNCARTCNMGNTGGGCNCARGTN MGNGAYYTNACNYTNACNTCNGTNGTNGTNGTNAGYGTNTCNTAYGCNGCNTAYCAYYTN TAYAARACNTAYATHGARCCNYTNATHMGNGGNAARACNGTNCARGARAARMGNYTNGAY MGNYTNGARYTNCARGTNGARGARATHCAYAARTCNGTNAAYGARTCNYTNTCNGARATH AGYMGNACNYTNGCNGCNATHCARATGAGYATHAAYAAYCARAGYCARCAR--------- ------------------------------------------------------------ ---------------------------------------GARCCNACNATHGCNGCNAAR ATHGCNMGNTGGTGGMGNCARCAYAARTCNCARAGYATHYTNCAYCAYCARATHAARTGY GAYCCNAAYTCNATGATHCAYCAYATHTCNMGNYTNTCNGARTGYMGNTGYTTYYTNAAR AARGARMGNAARMGNYTN---YTNACNYTNATGGARYTNTCNGGNGCNAARGGNGAYACN TGYGCNGCNYTNGCNAGYYTNGAYGAYTAYATGGCNAAYTTYTCNTCNGCNYTNAAYTAY ATHGARCARGCNGTNAARATHGARCCNAAYAAYTCNGARTAYYTNTGGYTNAARGARAAR ATHTCNACNCARTGYCARATHATGMGNGARCARAAYGAYGCNAARAARCARATHGAYAAR MGNYTNYTNCARTTYCCNTCNATGAAYGARGTNCCNMGNGTNTCNGGNAARAAYYTNAGY GTNGCNGAYTTYCARAAYAARTTYYTNTAYCCNGGNAARCCNGTNATHATHACNGAYGTN GTNGAYGGNATGACNGAYTGYCCNTTYGAYTAYTCNYTNGTNATHGARAAYGCNGGNAAR ACNACNATHACNACNAARGARGTNGTNTCNGAYTCNYTNACNTGGGCNAARYTNGARAAY AARMGNGARACNACNGTNGCNGARTTYATHCAYGGNGTNCARGCNGGNATHGGNAARGAY GTNYTNTTYGAYNNNNNNYTNNNNATHNNNTGYCCNAARYTNGCNCARAARATHTCNYTN CCNGARTAYNNNNNNNNNAAYTTYYTNYTNCARACNACNCCNGGNTCNYTNTAYMGNGAR AGYTGGCCNAGYYTNTTYATHGCNCCNAARGGNGCNGTNACNCARYTNCAYATHGAYGCN TTYCAYTCNCAYTTYTGGATGGCNYTNTTYCARGGNGARAARAARTGGACNTTYTTYGAY GGNAARGAYACNGCNTTYYTNTAYCCNCARTGGGTNCARTCNATGGAYCCNGTNTTYGAR GTNGAYYTNACNCARCCNGAYYTNACNCARTTYCCNYTNYTNGCNYTNACNCAYCCNCAR CARTGYGTNYTNCARAARGGNGARYTNYTNTTYGTNCCNGCNGGNAGYCCNCAYTTYGTN GARAAYYTNACNCCNACNYTNGCNATHTCNTCNAAYTAYGTNGAYCAYTCNAAYTTYAAR MGNGTNTGYGARGARYTNAARAARAAYTCNTTYCARGAYCARMGNGCNCAYGAYYTNYTN TCNCARYTNCARGAYCCNGCNTTYYTNCARAARGTNGARGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------MGNGARTCNGAYMGNGGNGAR GAYACNAAYYTNCCNTCNCCNGGNYTNGCNCARAAYYTNYTNGCNAARTTYTCNACNGGN ACNGCNAGYAAYTCNACNCCNMGNTCNAARMGNGARATHACNCCNCCNAAYCCNACNATG GGNGGNGGNGARTAYGTNTCNGARCCNMGNGTNGTNYTNGARMGNTAYGARGGNAARGCN GARTCNGGNGTNTTYGARAGYGARCCNCARMGNAAYCCNGARGTNGTNACNTCNGAYTCN CAYYTNGAYGAYGCNYTNCCNGARCARGGNAARGCNAARAARTTYGCNGCNMGNTAYGCN CARATHGAYCARGARGGNAARAGYACNGTNGTNACNAARAARAARGARGTNACNCCNGAY MGNGAYACNGGNCCNGTNGARTAYGTNTCNGARCCNMGNGGNTTYGTNGARCAYTAYGAR GGNAARGCNGAYTCNGGNGTNTTYGARAGYCARCCNGARAAYATGCCNGAYGTNGTNAAR TCNGGNGARAARYTNGCNCARGAYGCNGTNCCNGARMGNGGNACNGCNAARAAYYTNGCN CARMGNTTYCAYCARATHTCNATHGARAGYGCNGCNAGYAGYGCNGGNMGNAAYAARMGN GARYTNACNCCNGAYCARAGYGGNMGNACNGARTAYGTNAGYGARCCNMGNTCNCARGTN GARTCNTAYGARAGYAARGTNGARTCNGGNGTNTTYGARAAYACNCCNYTNGARGAYACN GARGTNGTNAARTCNCARACNGCNGCNGARGARTAYGTNCCNGARMGNGGNTAYGCNAAR AAYGTNGCNGCNAARTTYAARGARYTNGARAAYACNGCNAARTCNCCNCCNYTNTCNCCN GGNMGNMGNAARGARTTYACNCCNCCNMGNGARGAYGTNACNAGYMGNACNTCNGGNATH TAYGARAGYACNCCNGARACNAARCCNGAYGTNGTNACNTCNTCNGARTCNCARCARGAR GTNATGCCNGGNGCNGGNACNGCNMGNTCNYTNGCNCARMGNTAYAARGARATHGARGCN CARAGYAARTCNCCNGTNACNTCNAARCCNAARAARGARATHACNCCNCCNCCNAAYGAR GCNGGNGTNTTYGARAAYAARCCNGARMGNTTYCARGCNGAYTAYAAYMGNCCNGCNGAR TCNGGNATHYTNGARAAYACNCCNTCNGCNCARMGNGARGAYGTNYTNAARAGYAGYGAY ---GGNAAYACNGARGTNGARYTNCCNGARGCNGGNTCNGCNMGNAAYYTNGTNAGYAAR TGGMGNCARATHGARTCNGARAGYGCNAARAAYACNTCNCCNGGNTCNGCNGGNMGNCAY AARGARTTYACNCCNCCNMGNGARGARCCNMGNATHATGCARAAYMGNAARTCNCCNMGN ACNCCNAARTCNCCNACNGCNCARYTNGAYAAYGGNGCNGTNCAYCCNTCNGARYTNCCN GGNCARTAYCARCCNCARAAYGARCCNCAYGTNTTYGARTCNAAYCCNGARCCNCAYCCN GAYGCNYTNMGNGARGCNGAYACNGAYAARAGYCAYGGNYTNCCNAARAARAAYCARGCN AARAARATGYTNGCNMGNTTYCARAGYATHCARGCNGARGCNAAYAARGARATGCCNAAR CCNGTNCCNAARAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CCNTTYGTN GAYCAYATGCCNGGNATHATGCCNAARGARGTNGARACNGCNAGYTTYCARGCNATHYTN CCNATHCARTGGCARCAYCCNACNYTNAARCCNATHTGYATHCAYYTNGCNGGNACNGGN GAYCAYTTYTTYTGGMGNMGNMGNGTNTTYACNGCNMGNCCNYTNYTNAARGARGCNGGN ATHGCNTCNATHYTNYTNGARAAYCCNTAYTAYGGNTCNMGNAARCCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGAAYMGNAGYGTNAAYACNAARYTNATHMGNGCNTCNATGAGYCARAAY TCNMGNGAYAGYGTNTTYTGYAARTAYACNCAYMGNAAYTGYACNCARAAYTGYYTNGAR GGNTAYGAYTAYTGYATHMGNCAYATHYTNGARGAYAARACNGCNCCNTAYMGNCARTGY GCNTAYATHACNAARGCNGGNAARAARTGYCCNTCNGCNGCNCCNAARYTNGARAARAAR GARGGNTTYTGYGCNTTYCAYACNAARAARGCNCARYTNGCNMGNCARMGNYTNGCNMGN AARMGNMGNCCNAARGARACNCCNGAYAGYYTNYTNGARGAYYTNGTNGTNACNACNTCN ATGATGGAYTCNAAYCAYAAYYTNGARCCNMGNMGNGGNAARYTNCAYAAYGAYAGYATH GCNTCNMGNGCNYTNGAYTAYGCNAGYTCNAGYGAYTCNGARGCNGARCCNYTNYTNGTN GAYCAYGCNTGGMGNGAYYTNGGNGAYAGYGAYGCNGARAGYATHGAYAGYGAYCARGAR GAYGTNYTNAARTAYGCNGGNGTNTAYACNACNGARGARGTNGCNCARATHYTNMGNGAY AARYTNATHMGNYTNCARGCNYTNTAYATHGAYCARTTYAARMGNYTNAARCAYATHYTN TTYACNAARMGNMGNAARTAYYTNCARGCNCARAARAARGARAARGARATHTTYGGNAGY YTNAARMGNTAYAARGAYGAYCCNCAYCARMGNGARAARTAYAARAARYTNTGYGCNATG AARMGNTAYCAYAARAARTTYGGNATGGARGCNYTNGTNCARCAYCARTCNACNCARMGN MGNYTNAARGTNACNGARGGNATGAGYCAYMGNCCNCARGCNCCNATHCARTGYAGYTTY GARGAYGARGGNYTNMGNTGYTCNCARACNGTNGTNCCNYTNAGYAARTAYTGYCARAAR MGNATHYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CARGARTTYCCNGTNATHACNGARCARGTNGARATHGAYAARCAR GTNYTNATHGARMGNATHGTNMGNYTNCARAARTCNCAYGCNMGNAARAAYGARAARYTN GARTTYYTNGGNGARCAYATHCARCARYTNYTNGARGARATHAARAARAARACNAARATH ATHCARAGYTAYGTNATGMGNGARGARGCNGGNACNYTNTCNTCNGARGAYATGGAYGCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARTCNAAR AARAAYGGNGAYGARAGYTAYCARACNTTYATHYTNCAYGAYGARGAYCAYACNYTNGGN AAYGCNYTNAARTAYGTNYTNAAYAARAAYCCNGAYGTNACNTTYGTNGGNTAYAGYATH ACNCAYCCNTCNGARAGYAARATHAAYYTNMGNATHCARACNTCNGGNAARCCNGCNATG GARGTNYTNAARCARGGNTTYAARGAYYTNCARAARYTNTGYGGNCAYATHYTNACNACN TTYGARTCNTCNACNAARTAYTAYAARGARAAYCAYATGGAY---CARGCNGAYATGGAY CARACN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARGAYGAYCCNGTNGCNTGYAGY CARATHGTNAARYTNTCNCCNYTNGCNATGTGGGAYYTNGARCAYTGYGAYCCNAARAAR TGYACNGGNAARAARYTNAGYMGNGTNGGNTTYGTNMGNACNYTNMGNATGAAYCARMGN TTYAAYGGNYTNATHYTNTCNCCNATHGGNACNAARTGYGTNGCNCCNGAYGAYMGNAAY ATHGTNGARATGAAYGGNGTNGCNGTNATHGAYTGYAGYTGGGCNAARYTNCARGAYACN CCNTTYGCNMGNATGAARGGNGAYCARYTNMGNYTNYTNCCNTAYYTNATHGCNGCNAAY CCNATHAAYTAYGGNAARCCNTGYAARYTNTCNTGYGTNGARGCNTTYGCNGCNACNYTN TAYATHACNGGNTTYGCNAARGARGCNGARACNYTNYTNMGNAARTTYAARTGGGGNMGN TCNTTYTCNACNYTNAAYAARGARYTNYTNGAYACNTAYAGYAARTGYCAYACNAGYCAR GARGTNGTNTCNGARCARGARAARATHYTNGCNCARYTNGARGARGAYGGNMGNCARAAY AARATGAARGAYTGGATGGARATGGAYYTNGAYACNGAYGTNTGYAAYCCNAAYMGNCCN ------ACNACNGARTCNAGYTCN------GARGARGARAGYGARGARGARAGYGARGAR GAYGAYTAYGARGAYGGNTGYGAYAARGAYAAYGARACNGGNGARGAY---GARYTNGGN CARAARATHGGNATGGARTGYGCNGCNAARCAYAGYAAYCCNGARTTYYTNATGGCNGTN GCNAGYCAYATGGARAAYCCNGAYGAYATGGCNCARCCNACNTTYATHTGYGAYTAYCAR AARGAYATHGTNAAYATHYTNATHTGYGTNAARGAYGARGTNGCNAARTGYATGCCNGAR GARACNAAR---ACNYTNATGGARYTNTTYCCNTCNAARGARMGNYTNACNGARGGNYTN MGNTTYATGTGYGARCAYAARGAYATHYTNCARAAYAARTGYATGGAY---GAYCAYACN CARGARTTYATHCARTGYTAYATGGGNAARYTNACNAARYTNCARGCNTCNGTNACNGAY GTNTCNAAYAGYGAYCARYTNAARGGNYTNGTNTGYAGYGTNATHMGNTCNGARGARCAR TGYTTYMGNGAYAAYAARGGNTCNTGYAGYAARGARTTYGTNGAYYTNGTNATHCARATG YTNGARAARTTYTTYCCNATGTCNCARTGYGGNGCN------CCNGGNAARAAYGAYYTN ATGAAYGTNYTNGGNAGYATHYTNATHCAYGGN------------------CARCCNCAR GGNAGYYTNAARTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GARGARTAYGARMGNAARYTNAARATHCAR AGYMGNAARTCNTAYAARACNGARCARGTNYTNTCNYTNCARGTNTAYAARYTNCARCAR GARCARAARACNTTYTCNGARGARAARGARAARGTNGTNGGNGARYTNGAYAGYYTNAAR ACNCARYTNGARGARGCNAAYTCNGARATHTCNAAYYTNMGNAGYCARYTNGARTTYAAR TCN---------AARYTNAARGARGTNYTNGAYTCNCCNGAYTCNAAYGARGARYTNGCN ATHAARAAYAARGARGTNATHAAYYTNCAYACNCARYTNCAYACNTAYCARGTNGAYATG GARAARAARAAYAARGARYTNGGNGARAARGCNAARGARYTNATHGGNTGYAARGARGAR GTNGARAARYTNAARMGNGARYTNGAYMGNYTNAARAAYCCNCCNGTNATGTGYGARGCN TCNAGYCARACNCAYGCNYTNTGYGARGTNTCNAAYYTNGARAAYGTNAARCCNTCNATG ATGGGNGARMGNGARMGNACNATHCARACNYTNCARGARGARYTNAAYGARYTNMGNACN CARGTNYTNGGNATGGAYGARMGNCAYGARAARGARAARGARCARTGGYTNGAYGARAAR AAYAARGTNATHMGNTAYCARAARCARYTNCARYTNAAYTAYGTNCARATGCARMGNAAR AAY--------------------------------------------------------- ------------------------------------------------------------ ---GCNGCNACNYTNAAYYTNGTNTGYYTNATHTAYATGYTNCARTGGYTNCCNACNGCN GARTCNTTYATHCCNTAYTTYGTNATHATGGGNGTNTGGGGNGTNACNGAYGGNTTYTGG ACNGCNCARGTNACNAGYYTNATGGGNYTNATHTTYCCNGAYMGNATHGARGARGCNTAY GCNGGNYTNMGNATGACNCARGGNYTNGGNGCNGCNGTNGCNTTYGGNTAYTCNAGYGTN TTYTGYATGACNGCNAARATHTAYATHACNGTNGCNGTNTGYTCNYTNGGNYTNGTNGGN TAYYTNYTNGTNGARGGNATGYTNAARMGNCARMGNAAYAARTCNGGNTTYYTNYTNAAR CARACNTCNGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AGYATHGAYTAYYTNAARGGNTGYATHGGNGTNGGNCARYTN AARGTNTGYTAYCCNCARYTNGAYTTYACNCCNAGYGCNYTNTTYGCNATGGGNTCNCCN ATHGCNYTNTAYYTNTCNYTNMGNGGNATHGAYGARGTNGGNGARTTYTTYCARYTNCCN ACNTGYCCNMGNGTNTTYAAYATHTTYCAYCCNTTYGAYCCNATGGCNTTYMGNYTNGAR CCNYTNATHMGNCCNTCNATGTCNCARGTNAARCCNGTNCARGTNCCNCAYTAYAARGGN MGNAARMGNYTNCAYYTNGARTTYAARGAYGCNGTNAGYMGNTAYGGNACNGAYATHAAR CAYAARATHATGGARTCNYTNAARAGYACNTGGAAYAGY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ACNAARGARCARGARMGNMGNMGNAARYTNMGNGAYMGNAARMGNATH CARMGNCARAAYGARGAYTAYGCNGARMGNGARMGNYTNMGNGCNMGNGGNMGNATHAAR GCNYTNMGNGARGAYCCNGTNTTYMGNGARGGNGARMGNYTNMGNGAYMGNGAYMGNMGN MGNAARGCNMGNYTNYTNAAYCARGCNCARMGNATGCARGARMGNGAYMGNGAYAARYTN MGNAARTCNATGATGMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARACNYTN GGNTTYTGYAARTTYGGNGTNACNTGYMGNTTYGCNAGYAGYCAYYTNGGNGARAAYCAR GARAAYATHGTNAAYAARGAYYTNTAYGAYACNATGAARGARAARCCNTCNTTYYTNAAY GCNYTNTCNGARGAYGTNMGNCAYAARYTNTGGAARMGNAARTAYGAYTTYTCNAARGCN ATGGARTCNGTNAAYAAYGTNCARAARGCNTTY---------------GCNTTYAGYAAY ATHAAYAGYACNGCNGTNACNCCNGTNTCNGAYAARAGYGCNGAYYTN------------ ------------------AAYAAYGAYYTNGCNACNAARGARGGNGAYGTNTCNCCNCCN ---------CCNGCNACNGARGCNGTNGAYYTNGGNCCNGTNGTNTCNAARCCNTCNCCN GAYMGNTGYCCNTCNGARGAYGGNYTNAGYAARGTNGTNGGNGCN--------------- ---------------------GAYCAYGARGAYGTNCCNATHMGNTCNMGNGARGTNAAR AARATHGAYTTYCAYAAYAARYTNTAYYTNGCNCCNYTNACNACNGTNGGNAAYYTNCCN TTYMGNMGNGTNTGYAARGAYTAYGGNGTNGAYATHACNTGYAGYGARATGGCNYTNGCN TCNCARYTNYTNAARGGNAARGCNTCNGARTGGTCNYTNATHAARMGNCAYCCNAGYGAR GAYATHTTYGGNGTNCARGTNTGYGGNGCNTAYCCNGAYYTNATGACNAARTGYGCNCAR GTNYTNACNGARTCNAGYAAYYTNGAYTTYATHGAYATHAAYTGYGGNTGYCCNATHGAY YTNGTNTTYMGNACNGGNAGYGGNAGYGCNYTNATGGGNAARGCNACNAARYTNGARCAR ATHTGYMGNAGYATGMGNGGNGTNATGGGNGARATHCCNYTNACNGTNAARYTNMGNACN GGNGTNTTYGAYAARAARAGYACNGCNCAYACNATHATHCCNMGNATGMGNGAYGCNGGN GTNTCNYTNGTNACNATHCAYGGNMGNTCNAARGARCARMGNTAYACNAARYTNGCNGAY TGGGARTAYATHGAYCARTGYGCNAAYYTNGGNAGYCCNATGCCNGTNTTYGGNAAYGGN GAYATHYTNTCNTAYGARGAYGCNAAYYTNCAYATGGCNMGNAARGGNGTNTCNGGNGTN ATGYTNGCNMGNGGNGCNYTNATHAARCCNTGGATHTTYACNGARATHAARGARCARMGN CAYTGGGAYATHTCNTCNTCNGARMGNYTNGAYATHTTYMGNTCNTAYACNAARTAYGGN YTNGARCAYTGGGGNTCNGAYCAYCARGGNGTNGARACNACNMGNMGNTTYYTNYTNGAR TGGYTNTCNTTYACNCAYMGNTAYATHCCNGTNGGNGTNYTNGARCARGTNCCNCARAAR ATHAAYGARMGNCCNCCNTAYTAYATHGGNMGNAAYGAYYTNGARACNYTNATGGCNAGY GCNAAYTGYGCNGAYTGGATHAARATHAGYGARATGYTNYTNGGNCCNGTNCCNCCNMGN TTYCARTTYYTNCCNAARCAYAARGCNAAYGCNTAYCAR------TCNAAYACNCARCAY ACNGARTGGATHYTNGARACNATHGAYCAYYTNMGNAARMGNAARGCNMGNCCNGAYYTN CARMGNATHTGYCAYGTNGTNMGNMGNMGNCAYGGNYTNCCNAGYGTNGTNACNGARGCN AARYTNGARAARYTNGTNGAYTCNGARACNGTNATHAARGTNGARTAYAARGGNAGYACN AGYTAYMGNAAYGCNTCNAARTGGMGNAARAAYATGATHGGNTGYACNGTNCARAAYTCN ACNACNGTNTCNACNAARATHATHGARGCNATHYTNGCNYTNTCNAARACNAGYGTNGGN GGNGCNAAYAARTGYTCNGAYAARGAR---------------GTNCCNGGNGCNTGYAAY ACNAAYGAYTCNAARGAYMGNCCNTCNTCNGTNGGNGTNCCNYTNGGNGAYATHGARACN TGGYTNACNAARTAYTGYGAYGGNTTYACNAAYYTNAARAGYCCNYTNCAYGTNGTNYTN CARMGNGARATHGAYGTNGGNMGNATHGARAARYTNGAYAGYGGNGGNTAYGTNATHTCN MGNGCNCARAARGAYGARYTNACNAAYGAYGTNGTNAARYTNGAYGCNAAYAARTAYGTN AARCCNGCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYCAY GAYMGNTTYGTNGARYTNGARAARGARATGGARGARYTNMGNGGNMGNYTNATHGARAAR GAYGGNATHGTNTCNGAYYTNCARMGNTCNAAYTCNTCNYTNYTNGARYTNYTNGARAAR AARGCNGAYGGNGAYAGYAGYYTNGGNAAYMGNYTNGCNAGYCAYAARYTNGARGCNGAR YTNAARAAYYTNMGNGGNGARMGNGARCARATGGTNGCNGTNGTNAGYGARAARTCNMGN GARAAYTCNTCNYTNAARTCNGARATHCAYMGNYTNATGGAYYTNGTNGCNGCNGGNCAR GCNGCNYTNGCNAARGTNCAYCARGAYAAYGTNTCNYTNGARCARMGNCARCARTCNCCN CCNMGNGAY---------GARGARGAYGARATGAARMGNGARGCNYTNAAYAAYATGGCN MGNYTNGTNMGNGAYAARGAYACNGARATHGARGCNYTNACNCARAARAAYAAYACNYTN YTNGCNGTNYTNCARGAR---TCNAAYGARTCNAAYGCNGCNGCNCAYYTNGCNCCNYTN YTNAARGAYAARGARACNYTNACNCARCARATHAAYTCNATGYTNACNGARMGNGARCAR YTNATHTCNTGYGTNACNCARAARCAYTCNGARTCNYTNGCNTTYCAYGCNGARGTNCAR MGNYTNTCNGGNATHYTNATGGARACNCARGARGTNGCNGARAARGCNAARGCNGARTAY GCNGCNYTNATHCCNTCNTTYGARGGNAARAAYCARGCNYTNYTNACNACNCARCARGAR YTNATHGARTGYAARCARAARYTNACNGAYYTNGARATHMGNCAYGGNGARYTNATGACN CARMGNTCNAGYATHCARCARCARAGYCCNGAYTCN------------CCNACNAAYGAY GAYYTNGARGCNGARYTNGARAARTAYAARMGNYTNGARTCNGAYTAYAARTCNATGGTN YTNGARMGNGAYGARCARATHCAYAGYYTNTCNCARAARGGNAARGTNTTYGARGAYGCN GTNTCNTCNAARGARGCNGARTGYACNCAYYTNMGNAARCARYTNGARAAYTCNAARTTY CARYTNACNGGNYTNATGGCNGARATHGCNGAYGTNAARTCNGARMGNGARGTNATGCAR MGNAARMGNGAYAGYCARGGNGARGARTCNGTNAGYYTNMGNAAYAGYYTNAAYCARATG ACNYTNACNGTNAARGAYMGNGAYCARCARATHGTNTCNYTNAARGAYCARATHTCNACN YTNAAYTCNGTNYTNCARAAYCARAARGGNGAYGARGAYCARGTNAGYCARYTNATHMGN GAYCARGARYTNGCNGTNGCNGCNAGYMGNCARYTNCARCARGARMGNGAYMGNAAYGCN ATGYTNGCNGARCARMGNTTYCARGARTGYGARGCNYTNAARACNGARATHTCNTCNCAR AARGAYAARATHTTYAARYTNGGNMGNGARYTNGARMGNYTNMGNAGYCAYYTNATHGAR ATHGARGARGGNTAYACNAARGARGCNATHGARGCNGARGARMGNGARAARGARYTNMGN AAYAARYTNGCNGTNGCNGARGARCARYTNYTNACNTCNTCNTCNCAYGTNCARYTNGCN AGYCARGARTCNCARMGNCARATHGARAGYYTNCARGARCARYTNCAYCAYATHGCNTCN CARMGNGAYGCNGCNTAYATGCARGTNGCNACNACNCARGAYCARTGYCARCARTAYGCN GCNTCNYTNAGYAAYYTNCARYTNGTNYTNGARCAYTTYCARAARGARAARGAYTCNGCN ATHGCNYTNGARACNGARAARTAYCAYGAYCARGCNAAYTGYYTNAGYAAYAARGTNAAR GARYTNGARAARGARYTNGARGCNACNMGNGGNGAYYTNACNGARGCNYTNGAYGGNYTN GARGCNGCNTCNMGNYTNAGYGARCARYTNGAYMGNAARGARGARGCNYTNATGGCNYTN AARGARGARGTNCARYTNMGNGARCARACNYTNAARGGNGCNGARGARGARATHGCNMGN YTNAAYTCNAGYAARGARGCNAARGTNGAYAARATGYTNATGCAYAAYATGGTNYTNACN TGGYTNACNTCNCCNGARAARAARMGNCAYGARATHGTNCARYTNATHGGNCAYGTNYTN GAYTTYAGYGCNGAYGAYTTYTCNAARATHGARTCNGCNCAYAGYCARGAYAGYYTNTGG ATHGGNTTYTTYAARMGNTCNTCNTCNAARTCNCCNCARTCNACNCCNAGYAARGGNGAY CARTCNTTYTCNCARYTNTTYGTNAARTTYYTNGARAARGARTCNTCNCCNGCNCCNGCN CCNTTYCARYTNCCNGTNGARGCNATGGCNGCNGARGCNCARCARMGNCAYAARACNGCN TTYAAYCCNTTYATGGCNCCNMGNCAYGTNACNCAYGGNAAYGARGCNTCNGGNYTNTCN TCNGGNTCNGCNTCNCAYYTNYTNYTNCCNCARGAYAAYCCNCAYCCNTCNCCNYTNTTY GCNCCNGTNACNAGYGTNTCNAGYACNGGNGARAGYGCNATHYTNAARGAYGTNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AGY GGNTCNGGNCARCCNAARYTNGTNACNMGNACNGTNGGNAARGARGTNCAYYTNATHGAR AARATHGGNAGYGGNMGNTTYGGNGTNGTNTGGMGNGGNAARTGGYTNGGNGAYGAYGTN GCNGTNAARAGYTTYACNTCNYTNGARGARACNAGYTGGMGNCARGARATGGARATHTAY AAYACNGGNATGYTNAGYCAYGARAAYATHYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGYTNTTYAAYYTNGARGAYTGGAARCARGGNATGGAYYTNYTNTGYGARGAYYTNAAY MGNAARYTNGTNTTYMGNAARCAYTTYGAYTGYYTNTCNMGNTTYGCNCCNMGNATHTCN GGNTGYATHYTNATHMGNACNCARATGTTYAARAARGCNATHYTNGAYGCNGGNATGGCN ACNCAYAARACNYTNCAYGAYATHACNTGYAAYTTYGCNGARAAYATHGTNAAYTGYYTN GARMGNCCNYTNGGNMGNCARTGYCCNATHCARGTNGTNGAYACNATGGTNACNGCNYTN CAYMGNTTYYTNCCNCCNGCNTGYGCNCCNYTNCCN------------------------ ---------GCNAARGAYGCNAGYGAYGTNACNGTNYTNGARACNGTNATHYTNGARGGN GGNGGNGGNATGGGNGAYTCNGGNATHGARATGGAYTTYTCNAAYTTYYTNGGNAAYGAY GARGAYTCNGCNGTNGARCARCARAARTAYTAYGARYTNAARAGYAARGTNGTNGTNGGN AGYCCNGTNACNGARATHAARAAYGCNAGYATGCCNATGMGNACNAAYYTNAARCARCAR YTNCARMGNCARCARYTNTAYGARCARGARAARMGN---CARAARGCN------------ CAYGTNACNAGYTCNATHGGNATHAAYGTNCCNCAYGTNGTNGARTCNTCNCCNGTNCCN TCNAAYGTNYTNCARGTNMGNACNCARYTNCARCAYCCNACNAARTAYCAYGTNMGNCAR AAYCARAARMGNCARGTNCARAAYTTYYTNCARGARCARCARGGNGGNCAYATGCCNATG CAYTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGYTNCARGAYMGNATGGAYMGNYTNCARGAYGCNYTNAAYGCN TAYGGNCCNAAYTCNCARCAYTTYYTNAARGAYTCNGTNGCNAGYCCNTGGGARMGNGCN GTNGCNGTNAAYAARGTNCCNTAYTAYATHAAYCAYGAYACNGARACNACNCARTGGGAY CAYCCNCARYTNACNGTNATHATGGAYCARYTNATHGAYATGAAYAARATHMGNTTYGCN GCNTAYMGNACNGGNATGAARYTNMGNTGGYTNCARAARGARYTNCAYYTNCAYACNGTN ACNYTNCARATGGCNATGGARTCNTTYGAYAGYCAYGGNYTNMGNGGNMGNAAYGAYAAR YTNATGGAYGTNGGNGARATHATHGARTGYYTNTCNTCNATGATGGARTCNGCNGCNGGN CARCAYCCNGAYGTNGTNAAYGTNCCNYTNTGYGTNGAYYTNACNYTNAAYTGGATHYTN GAYGTNTAYGAYAGYGTNMGNAGYGGNAARATHMGNGTNYTNTCNTTYAARGTNGCNGTN GTNYTNYTNTGYCARGCNCARYTNGARGAYAARTTYMGNTAYATHTTYMGNYTNATHGCN GAYGCNAAYGCNTTYGCNGAYCARMGNAARATGGGNYTNYTNYTNCAYGAYTGYATGCAR ATHCCNMGNCARYTNGGNGARATHGCNTCNTTYGGNGGNAGYAAYATHGARCCNAGYGTN MGNAGYTGYTTYGARAARGCNAAYAGYMGNCCNGARATHGARGCNTAYCAYTTYYTNGAY TGGYTNAARYTNGARCCNCARTCNATGGTNTGGYTNCCNGTNYTNCAYMGNGTNGCNGCN TCNGARACNTCNAARCAYCARGCNAARTGYAAYGTNTGYAARGAYTTYCCNATHYTNGGN TTYMGNTAYMGNTGYYTNAARTGYTTYAAYTTYGAYGTNTGYCARAAYTGYTTYTTYTCN GGNMGNACNGCNAARAGYCAYAARYTNGCNCAYCCNATGCARGARTAYTGYACNACNACN ACNTCNGGNGARGAYGTNMGNGAYTTYTCNAARGTNTTYAARAAYAARTTYAARTCNAAR MGNCAYTTYAARAARCAYCCNMGNMGNGGNTAYYTNCCNGTNGARTCNCAYYTNGARGGN GAYAGYYTNGARAGYCCNAAYCCNTCNCCNCARCAYAGYATHTCNCARGAYATGCAYTCN MGNYTNGARATGYTNACNAGYMGNATHGCNGARGTNGARCARMGNCARGGNGGNTCNGCN GAYYTN------------------------------------------GARGAYGARCAY CAYYTNATHGCNCARTAYTGYTCNAGYYTNAAYGGNGARCCNAAYTCNCAYGCNYTNAAR AGYCCNATGCARATHATGATGGCNGTNGAYGCNGARCARMGNCAYGARYTNGARTCNATG ATHCARGAYYTNGARGAYGARAAYAARACNYTNCARGCNGARTAYGAYMGNYTNCARATG GCNGCNCAYGARMGNGCNTCNGAYMGNYTNMGNYTNGGNTCNGGNGARGGNGAYAGYGGN AGYCARGGNCARYTNAGYMGNGAYGARGARATGYTNGARGARGCNAARYTNYTNMGNCAY CAYAARGGNMGNYTNGARGCNMGNATGMGNGTNYTNGARGAYCAYAAYTCNCARYTNGAR TCNCARYTNACNMGNYTNMGNCARYTNYTNGARCARGCNCCNGGNGAYAARAGYCAYATH TCNYTNGAYTCNTCN---MGNACNACNCCNYTNACNACNCCNTCNTCNTCNCARAGYTCN TTYCAYATHGGNTCNAAYAGYTTYMGNATGGCNCCNCARATGGARTCNACNCCNCARTCN AAYGGNCAYAGYGCNATGAGYYTNACNGAYGAYCCNGAYYTNAGYGGNATHATHGGNAAR GTNAGYAGYCCNCCNCARTAYAAYGCNATHAARACNAARCCNGGNAAYGTNAGYGAYYTN TTYCAYATHGCNGGNGARYTNGGNGARGCNGTNGGNTCNYTNGTNACNGTNATGACNGAY GARGAYAARTCNAARAARAARAARAARGCNGAYGAYMGNYTNAGYAAYTCNAGYGARGAY GARGGNGARGGNTCNCAYTCNCARCCNGARAARGGNAARAARAARMGNAAR---GARTCN GGNGARGARGARGAYGARTCNGARAARGARCARTCNCAYTCN------AARAARGARMGN AARAARGGNAARCARCCNTCNTCNTTYGGNGTNGTNGAYACNAARYTNYTNMGNGAYCAY GGN---------------------------------------AARAARAAYGTNAARMGN AARCCNAAYCARGTNAAY---------------------------------------MGN GCNYTNGAYTAYYTNMGNYTNTGGAARAARAAYTTYAARTCNTGGAARTTYAGYAARYTN TAYCARGCNMGNYTNATHAARATHYTNTAY---GARCCNGTNGTNACNGARGARGAYTTY GARATHTGYYTNCARTAYTTYGARAARTGYCARGGNAARGCNMGNGARCARYTNAARGCN GAYGCN---------------------------GCNGGNYTNAARYTNGCNTAYATHGAR GGNTGGAARYTNATHAAYATHGCNAAYGARYTNTTYGGNTTYACNGGNTGGTCNCAYTCN GTNAGYAAYCARACNGTNGAYTTYGTNGAYCAYGTNAAYGGNAARTAYTAYGTNGGNGTN TCNGCNAAYGTNMGNGTNACNYTNAARAGYGGNGTNTAYCAYGARGAYGTNGGNTAYGGN GTNAGYGARGGNATGMGNTCNAARGCNYTNTCNYTNGARAARGCNMGNAARGARGCNGCN ACNGAYGGNYTNAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------TAYYTNCCNTGYGAYGAYTTYATGAARTTYCARGAYGCNYTN AARMGNYTNMGNYTNATGGAYGAYMGNATHATHCAYGCNYTNAAYAARAAYYTNCCNACN CARTCNTTYCARGGNAGYGTNGAYGTNGCNTCNAAYTGYMGNCAYATHTAYGAYGAYATH CARACNTCNTAYAGYCAYMGNGARAARTCNATHCARCAYTGYATHMGNYTNGTNAGYGAR GAYGTNAARAARYTNAAYGARAARMGNCARAARGAYCCNGAYAGYYTNGAYGTNATHAAR TCNYTNMGNATGGARCARACNAARYTNMGNYTNATGCARCARGARATGAAYGTNGARGAR GTNGTNAARGAYMGNACNYTNAARGTN--------------------------------- ---------------------------------------------------------TCN CAYATGTTYGAYGGNAARTTYATHCCNCARGTNACNGARAAYATGGAYTGGACNCAYGAR AARGCNTCNYTNGAYATGTTYGAYTAYATGATHGARGARCAYGGNTTYATGAARCCNGGN GGNGTNYTNCAYAARCAYGGNYTNGARGAYCARGAYATHGTNTTYATHAARGARYTNATH AAYGGNCCNGARAARACNAARGAYGTNGAYTGGCCNTAYMGNGGNMGNAARMGNGARAAR GCNTTYYTNTAYGARATHGTNTCNAAYAARMGNACNGGNATHGAYGTNGAYAARTGGGAY TAYTTYGCNMGNGAYTGYCAYCAYYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHYTN ATHCCNGAYYTNTCNTCNAARATHTCNGAYCARGARYTNAARAAYACNGTNTCNGAYYTN TCNTTYTTYGAYGARATHCARGTNGARGAYCCNMGNGTNCAYGARYTNGGNAAYAARGTN GGNCARCCNAGYCCNTTYCARYTNYTNMGNGARTGYYTNMGNMGNAAYTTYGGNATGGGN ACNCCNCARTGYTCNGTNAAYACNACNGCNYTNAARAAYCARAARTGYGARTTYACNYTN AGYGTNGGNAARCAYTCNGCNACNATHGTNGCNAARAAYAARMGNGAYGGNAARCARYTN GCNGCNCARGCNATHYTNGCNAARYTNCAYCCNCAYGTNCCNAGYTGGGGNTCNYTNYTN MGNYTNTAYGCNACNAAYGTNGARAARCCNATGGARAARGTNGARGARATGAAYGARATH AARACNCAYGTNCCNAAYAARGCNGTNYTNGARAARYTNMGNAARGARATGMGNAARYTN CAYAARCARAARGARGCNATHCARTCNAARGGNAARATGYTNATHTCNACNAARGAYYTN CCNAGYAARATGTCNTGYGTNGAYYTNATGGTNGCNTTYGGNYTNCAYYTNGGNGCNTGY TCNGCNTGYYTNGCNGTNCAYMGNGAYGGNAARACNGARGTNATHGCNAAYGAYYTNGGN GAYMGNGTNACNCCNACNGTNGTNGCNTTYACNGAYCAYGAYATHTCNGTNGGNGCNGGN GCNAARCARGGNGCNGTNMGNAAYGCNGCNAAYACNATHGCNCAYGTNAARCAYATHGTN GGNAGYGARAGYGARGAYGCNCCNGTNAARGARTAYATHCARAAYCAYCARGTNGAYGTN AGYAGYCARAAYGGNTCNGTNATHTTYAAYGTNGARCAYCARGGNAARAARGTNCARTAY ACNCCNAGYMGNATHYTNGARYTNATHTAYAAYAARATGYTNGARACNGCNCARAGYCAR GTNGGNAGYGGNGCNAARGAYGCNGTNYTNGCNGTNCCNTCNGAYTTYACNCARCARCAR MGNAAYATHYTNAGYGARGCNGCNTCNAARGCNGGNTTYAARGTNYTNMGNYTNATHAAY GARCCNTCNTCNGCNATGYTNGCNTTYGAYGTNGGNCARTTYGAYGARTCNGARCARGAR TTYAARACNYTNGTNTAYMGNTTYGGNGGNACNTCNCAYGAYGCNACNATHATGAGYGTN CARCAYGGNATGTAYTGYATHAARACNAARGCNTCNGAYAAYCARTTYGGNGGNGAYAAR YTNACNGARGTNYTNCARGGNTTYYTNGCNTCNGARTGYAGYMGNCARYTNMGNTGYGAY GTNACNGARAGYAARMGNTCNATGAGYAARYTNAARYTNGCNGCNGARMGNTGYAARCAY TCNYTNAGYTCNYTNTCNAAYGCNCARTGYAGYGTNGARTCNATHTTYGAYGGNYTNGAY TTYTCNTAYAAYGTNTCNMGNGCNMGNTTYGARAGYYTNTGYATGCCNMGNATGTCNCAR TGYACNCARYTNGTNCARCARGTNYTNAAYAGYGCNGGNTGYACNAARGARGAYATHTCN AARGTNATHYTNTGYGGNGGNGGNGCNAARTCNCCNATHGTNAARAARGTNYTNACNGAY TTYYTNCCNTCNTCNGCNYTNYTNAAYTCNATGGCNGARGAYGARATHATHGCNATHGGN GCNGCNAARGARGCNGCNYTNYTNGARGGNGAYGAYGAYGAYGAYGTNGARATHCARGAR CARMGNTCNAAYGCNTTYAARTCNYTNTCNAARGCNATHTGYYTNMGNGTNAAYTCNCCN GARYTNAAYGTNATHYTNCCNCARAAYTGYYTNATHCCNGCNMGNMGNCARCAYACNYTN ACNYTNCCNACNACNCARACNAGYGTNAARYTNGARATHYTNCARGCNTCNGARCCNATH ACNTCNGAYACNGARGCNCARYTNYTNGCNAARATHGTNYTNMGNGAYYTNCCNCCNGGN TCNAGYATHAARTCNAGYTTYCAYYTNACNMGNCCNACNGCNCCNACNTTYCCNGAYGCN TTYAGYATHTCNTTYCARGARATHGARGTNYTNTTYGGN------------------CAY GTNYTNAGYACNAAYAAYGGNTCNTGGTAYTTYGAYTTYGCNAAYMGNMGNGCNMGNTTY GAYCAYAAYMGNGGNCARACNAAYAAYTTYTGYGAYTAYCARAAYYTNAGYCCNAARGAY CCNAARGCNGGNTGYCARYTNTTYTTYACNCCNACNGARGAYYTNATHGTNTTYTAYCCN GTNGTNCARAAYTGYTGYMGNYTNTGYGGNAARGAYGARGGNTGYACNATHYTNAARCCN AAYTGGYTNCARCARGAYTCNAARYTNATGTCNGTNGARGARATHAAYGGNGTNAARTGY TAYGGNTGGGCNAARCARGGNGCNGTNGCNGCNGCNGAYACNTGGTTYGCNACNGCNGAY GGNGTNCCNTGYMGNTAYCAYGARGTNGTNGTNCAYATHGAYCAYAAYYTNACNTTYGTN CCNCARACNTTYAARGTNGGNCCNCARGAYCCNGCNYTNTTYCARGTNCCNTCNTGGTGY AAYAAYACNTGYCCNCAYCCNTAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYAARACNCCNGTNYTNGAYTCNCCNGARGAYGAR------ YTNTCNGARGTNACNGARGARGTNGARGARMGNCCNAAYCARMGNCCNCARGCNGCNMGN AARGCNGAYGAYMGNTCNAAYGCNGAYGCNACNCARGARACNGAYTCNACNAARTCNAAR TCNAARAARTAYTTYGARTTYGARATHCCNYTNCCNGAYGARATHMGNGARGGNATHYTN YTNYTNGGNGAYAARCCNCCNCCNGARCCNGARAAYATHMGNATHGCNATHCAYCARGGN CARTTYGARGARATHATHGCNATGGCNACNATHGAYTTYCARGAYATHAARGGNYTNACN YTNGARACNATHTGGYTNCCNGCNCCNACNGGNGAYGAYGAYGTNGCNGTNGTNAARTCN MGNTCNAAYTCNYTNAGYGGNGCNTCNAGYYTNGGNGGNGARTCNYTNAAYGAYTCNATG GAYATHCCNATHATGATGGAYGAY------GAYCARTCNGGNATHGGNYTNGTNTCNTCN ACNCCNMGNGAYGAYATGTTYAARGTNAARGAYCCNYTNCCNTTYCCNYTNTAYACNYTN CAYGGNGGNAARACNGAYTCNYTNCAYGTNCCNTGYGGNAAYGTNCCNYTNTTYYTNTAY TGGGGNAARMGNCCNMGNCCNYTNAAYTTYAAYMGNCARTGYGGNACNYTNGGNATHTAY GAYATHGTNTAYGAYATHACNGGNTAYGAYATGACNACNACNTCNAARGARGAYYTNCAY AARGARATGGTNGAYGARGCNYTNTCNGTNGCNGCNTTYACNCCNGAYCCNGAY------ ------------------AARGARACNGTNYTNAARTCNGARTAYGAYAARYTNGTNGAR AARCAYCARGARGARATGATHTAYYTNCARGARCARTAYGARAAYMGNYTNCARGARYTN GTNCARAAYYTNCARACNATGCARGCNGARAAYGARCARGTNCCNCARATGATHTCNCAR CARTCNACNCARCARMGNCCNYTNTCNCARGCNTCNMGNGTNAGYACNACNCCNGGNGCN ATGACNCCNATHACNTCNAARMGNTCNGARMGNTCNGAYCCNTCNTTYTAYGARAGYATG GCNYTNCCNCARACNGGNCARAGYATGMGNACNTTYAGYMGNGAYAARACNAAYGTNGGN GARATGGARMGNGARAARAGYATGATGTCNCARAGYACNGCNAGYACNMGNYTNAARCCN YTNCCNCAYMGNAGYGCNMGNCARACNAARAAYTTYMGNATHGGNAARCCNYTNCCNAAR TGGGGNGARACNYTNCCNCARGAYTTYTTYGAYMGNYTNMGNYTNTGGGARGARGARAAR AARCARCAYAARCARGARYTNAAYGARAARACNYTNAARGAYATHAARGAYAAYYTNGAR AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TAYYTNACNAGYAARAGYGAYTGYAGYAAYGARYTNAARAAYATHTTYGGNTAYGARGCN GTNGTNAGYGGNTAYGAYCCNMGNAAYATHGGNACNGGNCCNACNTCNTGYACNATHMGN ATHACNTCNGARTCNGGNTAYCARGGNGTNCARYTNCARATHGTNATHATHTCNGCNGAY ATH--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNTCNMGNATGCARATHTTYAAYMGN AAYGGNCAYTTYYTNMGNMGNATHGCNATHMGNTTYATHGAYATHGTNGCNGGNYTNGAY ATHACNCCNGARGGNCAYATHGTNGCNGTNGAYAGYGTNTCNCCNACNGTNTTYMGNYTN ACNGARGCNGGNGARYTNATHAARTGGTTYGAYTGYAGYGAYTAYATGMGNGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CCNTCNGCNYTNTCNACNYTNATH CARGARAARGGNYTNAARYTNGGNGGNGTNGTNGAYYTNACNTAYACNACNAARTAYTAY GAYGCNCARTTYTTYACNACNAGYGGNGTNGGNTAYAARAARGTNTTYACNGCNGGNCAY GTNATHCCNAAYGAYAARACNTTYGARCARTTYACNAARGCNATHAARTCNYTNGARAAR GARGGNGARGTNATHTGYGTNCAYTGYACNCAYGGNYTNAAYMGNTCNGGNTAYATGATH TGYMGNTAYATGATHGARGTNYTNAAYATHGARCCNCARACNGCNATHMGNYTNTTYGAR CARGCNMGNGGNCAYAARATGGARMGNGARAAYTAYMGNGAYGAYYTNYTNMGNMGNACN CCNGGNGTNTGGGCNCAYAAYGTNGAYGARTCNMGNATGGGNTAYGTNACNGTNTGGGAR YTNGTNYTNTGYTAYYTNGTNGTNGCNTGYGTNGCNAAYAAYCCNCCNTCNYTNTCNGGN AARGTNGTNTCNMGNGTNATHGCNAARGTNGGNAARAAYTCNMGNYTNYTNTGYCCNGCN AAYTCNGAYCCNTCNYTNACNCARTGGAARAARAAYGGNCARGCNYTNAAYCCNGGNTGG GARMGNTTYAARGTNTCNCCNAARGGNCAYYTNMGNATHMGNGAYGTNCARYTNYTNGAY GCNGGNYTNTAYACNTGYGTNGCNACNAAYGGNTAYGGNAGYATGAAYATHAAYTAYACN GTNATHGTNYTNGAYGARGARAAYCARGTNTTYCARGARGCNGAYAARYTNATHAARCAR TCNCCNGGNGARGAYATHTAYMGNGARGGNGCNGTNCCNGTNTTYGARGGNYTNTCNAAR ATGCARGARACNACNACNYTNAARAARCCNACNGGNTCNACNYTNMGNYTNACNTGYAAR GCNTTYGGNAAYCCNAARCCNCARGTNTAYTGGTAYAARGGNTCNGARYTNYTNAAYCAR ATGMGNGCNCARCCNACNYTNAARATHCAYAARGTNACNGGNGARGAYAGYGGNAARTAY ACNTGYGTNGCNAGYAAYMGNYTNGGNCARACNAAYTTYACNTAYAAYGTNYTNGTNATH GAYGARATHAGYCARCCNMGNYTNATHGCNCCNCAYCCNATGAAYAARACNGTNAAYGTN GGNGAYTCNGTNTCNTTYCARTGYTTYATHGARAGYGTNGTNGARCCNGARGTNAARTGG YTNAARMGNGTNGAYATHACNGAYAARAAYACNAAYCCNAAYGTNACNYTNATHCAYTAY AAYAARCARAAYYTNATGGTNYTNAARGGNGCNGGNATHYTNCARGCNAARMGNGAYGGN TCNTAYYTNAAYAARYTNAAYATHAARTCNGTNMGNCCNCARGAYGCNGGNATGTTYGTN TGYYTNGCNACNAAYMGNCARGGNTTYGTNAGYMGNCAYGCNTAYYTNCAYGTNATHGAR GGNGGNGGNTAYCARAAYTCNTCNCCNTCNGAYTCNCARMGNTCNTCNTCNCARTCNTCN GAYAGYGTNGAYGAYACNAAYYTNCCNATGYTNATHGGNYTNCCNGCNTGYGGNYTNYTN ATHATHATHYTNATHACNGTNTTYYTNYTNCARMGNAAYAAYMGNTGYMGNMGNTCNAGY ACNAAYACNAARGTNCCNMGNACNCCNGTNCCNCCNGCNGARMGNGAYGCNTAYTAYTAY AGYAAYTGYCARCARCARCAYYTNCARCARTCNATHAAYCCNYTNYTNATGTCNMGNGAY AARYTNCCNAARACNCCNACNCCNTCNGTNGAYATGACNGGNTCNGARTTYTCNTCNGTN TCNMGNAGYCAYCCNTCNCAYCAYTAYCAYAGYAAYCAYAAYTAYGGNTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CAYGAYCAYGAYGAYGAYGAYCAY TGYCAYYTNTCNGCNAARTAYACNGARTAYATHAARATHCAYYTNGARGAYYTNCARTCN AARTGYAAYCAYYTNACNATHTGYATHAAYACNYTNYTNTCNCARCARAGYCCNATHTCN GTNYTNAARGGNGAYAAYYTNGARYTNAARAARATHTGYGARYTNATHAAYGTNAARAAY AAYTCNGCN---TCNATGYTNGGNGGNAARTGYTCNYTNCARGARMGNATGGAYATHATG YTNGAYGTNGARAAYCAYYTNAARGAYAARATGGARAARAARGAYAAYTGGGARAGYGTN GCNGTNTGYYTNGARAAYAAYTAYGGNGAYAAYGARMGNACNACNTAYATHGGNGAYATH TGYGGNYTNGTNGARAGYMGNGGNGARATHTGY---TCNTAYGAYACNCAYAARCARGTN GARAARTTYATHAAYGARCARATHGAYCAYYTNCARTGYACNTGYAARGCNYTNAAYCAY ACNGAYCAYCAYCAYGAYAGYGARYTNTCNATHGCNGCNATHGCNGGNATHGGNGTNGGN GCNTTYYTNYTNTGYYTNATHTTYGGNYTNATHTTYTTYTGYTAYGTNMGNAARCARMGN AARMGNMGNAARAARAAR---GGNCCNAAYGTNGTNTAYYTNCCNGCNGCNAAYAGYGAY AAYTGYCCNGTNTAYCARGARATHTTYGAYCARMGNTCNCCN---------CCNYTNAAY CCNCCNACNYTNCCNAGYMGNTAYATGTCNMGNCCNCCNGGNAGYCCN------------ ------GAYGAYACNGARTAYYTNGARCCNGTNCARGCNCARGCNGCNGGNAGYTAYMGN AARGCNCCNGCNCCNYTNCARMGNYTNGTNAAYAAYCCNGGNTAY------GARGTNGAR GCNCCNCCNGARTAYAGYGARACNGAYCARACNTAYGAR---------------GAYGCN GTNYTNATGGAYGCNGARGCNGCNAGYACNTAYTTYGARCCNATHGTNACNCCNAARACN GARAARACNGAYGAYAAYGTNMGNAARGAYAAYAAYGARGARTAYCARGCNYTNCARGAY ATHGAYAARGAYAARAARYTNGGNCCNYTNCCNGCNCARMGNGTNAARAARGARGAYMGN GTNACNGARTCNGARTAYTTYGARYTNGARATGYTNGARGARGGNAGYGTNACNATGGAR AARAARYTNACNAAYMGNCARTCNCCNGCNCCNGGNCARTGYAARAAY---GGNGCNACN AGYGARMGNAARTCNGAYTTYACNCCNAAYMGNMGNGGNCAYAGYMGN---MGNTCNGGN TCNGGNGGNGGNGCNAARACNCARGAYGTNGGNCARACNCCNMGNCCNAGYCCNATHCAY AARTGGGAYMGNTCNGTNGGNAAYMGNMGNCARMGNCARMGNAGYGGNTAYGAYTAYMGN CARMGNGARGARGTNGARGARCAYGAYGAYGTNTTYGAYGTNYTNAGYACNGGNTCNMGN AARGGNAAYYTNAAYCAYYTNYTNAAYTTYAARTTYYTNCCNMGNMGNCARAGYCARAAY GAYGAYCAYMGNTGGCAYGAYMGNMGNCAYTAYAAYTCNCARGGNMGNGGNGGNTTYMGN AARMGNAARMGNTAYAARAARGARCARTTYYTNCARGCNAGYTGYCARTTYGTNGTNMGN GAYACNGGNGAYTAYGCNGARCARGCNATHAAYTCNGAYGCNYTNGTNGAYTGGAAYATG ATHGARYTNGTNMGNAGYTTYTGYACNGARCCNGTNAAYTGYCCNATHTGYYTNGARATG CCNACNGCNGGNAARATHACNAARTGYGGNCAYACNTAYTGYTGGGCNTGYATHYTNCAY TAYYTNAARYTNGGNGARGGNGARGCNMGNAARTGYCCNATHTGYTTYGARACNGTNGAY GTNGARGAYYTNAARAGYGTNCARTGGATHGAYGTNCCNAAYTTYAARGTNGGNGAYACN ATHGAYATGMGNYTNATGAARAARGCNAARGGNAGYGTNATHAGYATGCCNAARGAYCAR TGGGARGAYMGNYTNGGNAARCCNATGAAYGTNCARGAYGGNGTNAAYACNGARTTYATG AARYTNYTNGTNGCNTCNTCNGAYCARATHCARACNGARGTNATHGARACNGARMGNGCN TCNYTNACNGTNCARYTNGARGARGCNGARGAYTCNGARACNTGYTTYATHCARATGGCN YTNGARTCNYTNGARGCNMGNGARAARTCNYTNAAR------------------------ ------------CARGTNTTYCARCARACNGCNGGNACNAARGAYAARGTNCARATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AARGCNCARGAYAARACNTTYGAYCARAARAAYGAY GAYATHTCNGARTCN------------------ACNTCNACNAAYGARACNACNGARMGN ACNGGNAAYGAY------------------------ATGGCNATHGAYYTNGAYCCNCAR ------------TAYTCNMGNCARMGNCAYGAYAGYGARTGYTCNYTNCCNTTYGGNTCN CCNCCNTGYCCNTTYCCNYTNGTNCCNGAYCARGARGTNAAYCAYGTNCCNYTNACNYTN GARGARACNGCNGAYCAYYTNGARYTNCCN---------ATHGAYATHCCNCARACNATG GAYAARCARCARCCNAARATGTCNAARGAYAAYTAYTTYTTYTAYCARGCNTCNACNGGN CARCARATHTAYYTNAAYTCNYTNAAYGCNCARTGYATGGCNMGNGARTAYGGNTCNYTN GARGARAGYCCNAARGAYYTNGARGGNACNATHGTNGCNATHGARMGNATHTTYATGACN GARGAYGTNMGNAARMGNYTNMGNTAYYTNGAYCAYATHCCNYTNACNTGYGARGTNCAY ATHGTNGARYTNAARYTNAARCCNCCNGTNGTNAGYAARGARACNYTNAARTTYTTYGAR GCNGCNTTYGAYAARAARMGNAARCARMGNCARCARAARGARMGNGARGAYAARMGNMGN GCNAARAARATHGARATGGARCAYAARAARAGYTTYGGNATHTAYCCNGARGTNCARATH CCNYTNGAYAGYYTNGARCARTTYCCNTCNCAYYTNTCNGCNAGY--------------- ------------TGGYTNAARAGYTCNTAYAAYATHGAYGTNGCNGAYGAYTGGYTNTCN ACNTGYATHGARTTYATHMGNCARGARACNCARAGYTCNAGYCCNAGYYTNGARGAYYTN AARAGYYTNGTNTTYGARCARTGGYTNYTNTCNGAYYTNTCNGARATHGGNAARCCNTCN YTNCCNAAYGAYGTNTTYACNTGYGARAARTGYYTNYTNGARCAYGTNTAYCCNYTNCAR ATGATHTCNATHGTNGAYGTNTCNACNCCNYTNTTYGGNCARYTNCARAARTTY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYAARGAYACNGARAAY GAYAAYAAYAAYGAYGAYATGTTYGARGARAGYCAYAAYTAYMGNTTYTCNCAYGCNMGN YTNCCNGARGARGAYGTNATGGAYGAYGARGTNAAYGAYGCNAARCCNCCNACNGCNCCN ACNAAYATGGTNYTNTTYTAYACNTGGATGATHYTNGCNATHYTNGTNATGGTNATHGTN GTNTCNACNTAYCARGCNAARTGYAARGGNYTNYTNTCNAAYGGNAGYMGNCARCARACN MGNGGNGARGAYMGNAARMGNYTNYTNGAYCAYGARTTYGTNGTNACNYTNYTNGAYYTN CCNTGGGARCARGTNYTNTGYMGNAAYGTNYTNCCNTAYYTNACNATHCCNCARYTNTTY MGNYTNMGNACNGTNAGYCAYAGYTGYYTNTGYYTNGTNGAYACNTAYTTYAGYYTNCAR TTYCAYYTNAAYATHAGYCAYYTNGGNAARAARYTNACNTCNAARGCNTTYTCNYTNATG ACNMGNGAYAGYMGNTGYYTNAARACNYTNTTYYTNMGNGGNGCNAARTAYGGNYTNAAY AAYGARGTNTTYYTNCCNGTNYTNGCNAGYAAYTCNMGNYTNGARAARATHGAYATHAGY GGNTGYACNTCNYTNTCNGGNTGYGTNYTNTAYGCNATHGGNGTNAAYTGYCCNAARYTN AARCARYTNATHYTNMGNGAYTGYGTNACNTTYATGGARGARAAYTTYYTNTCNTTYYTN TGYGTNAARCARCCNGTNCAYYTNGARTAYYTNGAYATHTCNGGNTGYTGGAAYYTNGGN GAYGAYYTNGTNATHAARYTNGTNCARMGNTGYCCNAAYATHAARCAYYTNYTNYTNGGN AAYYTNTAYGGNYTNACNGAYMGNACNGTNTGYACNATHTCNCAYTCNTGYCCNGAYYTN ATHTCNYTNAGYATHGTNGGNTGYTGGMGNATHACNGAYCAYTCNATHAGYYTNATHGCN GCNTAYTGYCARAAYYTNAARTTYYTNGAYGTNAARGARTGYMGNGAYATHACNGARGAR AGYYTNGGNCCNYTNMGNACNMGNCARGTNAARATHGAYAARCCNGGNCCNCCNCCNTCN TAYYTNAAYMGNYTNGARTTYYTNAAYAARGCNCAYAARATHAAYGTNATGYTN------ GTNGCNYTNTTYGGNTAYTTYMGNAGYTCNTGYAGYTGGMGNGTNMGNATHGGNYTNGCN YTNAARAAYATHCCNTAYGARTAYGARGCNGTNCAYYTNGTNAARGGNCAYCARMGNACN GAYGARTAYAARAARATGAAYAGYTCNGGNTAYGTNCCNACNYTNAARATHGAYGGNCAY ATHYTNACNCARTCNYTNCCNATHYTNGARTAYYTNGAYGARMGNAAYCCNGARCCNCCN YTNYTNCCNAARGAYATGGCNGAYAARGCNGARGTNMGNGCNATHGCNGARATHATHAAY AGYGGNATHCARCCNYTNCARAAYYTNACNGTNYTNCARAARGTNGGNGAYACNAARYTN GARTGGGCNAAYCAYTTYGTNACNGCNGGNATGGARGCNYTNGARTCNTGYYTNAARAAR ACNGCNGGNACNTAYTGYTTYGGNGAYAARGTNACNATHGCNGAYATHTGYYTNGTNCCN CARGTNGCNAGYGCN---GCNMGNTTYAAYGTNGAYATGTCNMGNTTYCCNACNATHTGY MGNGTNAAYAARGCNYTNGARGARYTNCCNGCNTTYAARGTNGCNGAYGCNMGNMGNCAR CCNGAYACNCCNGARGARATGMGNATHGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGTCNGAYAARYTNACNACNMGNGTNATHCARGTNACNAAY ATHGCNCCNAGYTGYTCNAARGARCARYTNMGNACNYTNTTYGGNTAYYTNGGNMGNATH AARGARYTNGARATGTAYCCNCCNGAYGGNGCNGAR---GGNGTNGTNACNGCNMGNGTN GCNTAYATHGARTTYGARGAYTCNGTNACNACNGGNGTNGCNYTNCAYYTNAGYAGYACN GTNTTYATHGAYMGNGCNATHATGATHGTNCCNGTNATGGAYGGNAARATHCCNGAYGAR AGYTCNGCNYTNCARYTNACNCCNTCNGCNGTNGCNGGNATGYTNCCNGGNCARCCNACN TGGCCNGCNAAYGTNGTNTCNCARGTNACNGGNYTNGGNGCNAAYCARATHATHATGACN AAYGAYCCNMGNYTNACNTCNYTNGGNYTNCCNCARTAYCCNCCNYTNCCNGCNACNACN GAYCCNAGYAARATHGARGARATHMGNMGNACNGTNTTYATHTCNGAYYTNGAYGCNAAR GTNACNCCNGARATGYTNYTNTCNTTYTTYTCNCARACNGGNGARATHAARTAYATHMGN ATGGCNGGNGAYGARAAYGCNCCNACNMGNAGYGCNTAYATHGARTTYACNGAYCARMGN TGYATHGCNCARGCNYTNAGYTAYAAYAAYGTNGTNTTYCARGGNMGNACNGTNAGYGTN AARCAYGCNACNACNAGYATHGTNAARCCNACNCCNMGNTCNGARGCNTCNCARMGNGAR ATHGAYGAYGCNATGAARAARGTNAARGARGCNTCNAARYTNATHTCNGCNGCNGCNAAY AGYGAYMGNGAYAGYTCNMGNTCNCCNACNMGNAARMGNTCNMGNTCNAARGTNMGNAGY MGNTCNMGNTCNMGNTCNMGN---MGNMGNTCNMGNTCNMGNTCN---CCNMGNMGNMGN MGNMGNAGYGGNTCNMGNACNMGNMGNMGNTCNMGNTCNMGNMGNMGNTCNCCNAARMGN TCNMGNTCNCCNATGMGNMGNMGNMGNTCNMGNTCNMGNGGNMGNGTNCCNCARCCNGCN CCNCCNGTN------------TCNMGNGARMGNMGNMGNTCNMGNACNMGNTCNCCNGTN MGNMGNMGNMGNTCNMGNTCNMGNTCNAARTCNMGNCCNMGNMGNTCNMGNACNCCNCCN AARTCNTAYAGYMGNGGNMGNMGNTCNCAYTCNMGNAAYMGNMGNAGYMGNTCNMGNGAY MGNMGNGARAARAARGARMGNAARAARAGYMGNTCNATHTCNCCNCCNACNYTNATHMGN GARGGNTCNGCNTCNGTNGARGARGARMGNGAYAARTCNCCNTCNAARGGNAAYGGNMGN TCNCCNAGYCCNCCNAARACNAARAARMGNAGYCCNACNCCNAARAARMGNAGYMGNTCN MGNTCNCCNAGYMGNMGN---AARAARMGNMGNCAYTCNMGNTCNACNTCN---MGNAAR MGNTCNMGNTCNMGNAGYGGNTCNMGNTAYMGNGCNMGNMGNGAYMGNAARMGNAGYMGN AGYMGNGAYMGNAARCAYGAY---AGYAARAARAARAGYAGYMGNGAYAARGARGAYMGN AARAARGAY------AGYAGYTCNAARATHAARMGNGAYTAYGAYGARGARGARAARGGN TTYGCNAGYGAYMGNAGYGAYGARMGNGAY---AAYAAYAGYGARGGNGTNMGNTCNMGN GCNGAYTCNCCNAGYCARCCNCCNYTNYTNGARAARGAYACNGAYAAYCARCCNGTNGAY ATGGAYATGAGYGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARTCNGCNGTNACNGARGAYGCNTAY GAYMGNTTYMGNAGYACNGTNGARAAYTCNATGGGNCAYGARYTNAGYTGGAAYACNATH GCNYTNYTNTTYTAYGCNACNAARGGNGTNGTNTCNGCNGTNGGNAARAGYTCNCARGTN GCNACNCARGCNAARGARTTYACNYTNAARTAYATHAGYGAYACNTTYGTNTCNTGGATH ATGGARCARGGNGGNTTYGAYAGYATGYTNAGYGGNAGYGARTCNGAYCCNGARYTNGAY TAYACNGGNTAYYTNGARGAYMGNGGNGARYTNAARGCNGCNATHCCNYTNGTNGAYATG TGGTCNGTNGARAAYGTNCARGAYGGNATGYTNGARGAYCAYAARAAYGTNTTYCARGTN YTNTAYGARGAYGAYCARYTNTTY---CAYYTNTAYATHGTNGCNGARACNGAYYTNGAR MGNAAYTCNTGGGTNGCNGCNATHAARAARGARGCNGCNMGNTGYAAYGTNTGYYTNCAR TCNMGNTAYCAYCCNGGNGTNTGGYTNAARACNGTNMGNAARTAYAAYTGYTGYGGNMGN GTNCCNMGNGAYTCNCCNGGNTGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGYTNCAYACNGTN YTNTTYYTNACNTCNGTNYTNTTYGCNGGNACNTGYCAYYTNTGYATGATHAGYCCNCCN CARMGNGGNTCNATGYTNGGNATHAAYAARCCNGGNGCNACNGAYTGYATHYTNYTNACN TCNCCNTGYGGNGGNMGNGGNMGNACNGARGTNATHYTNGARYTNATHTCNGGNTCNAAY TTYACNGTNACNYTNATGAARAAYYTNAGYCAYTTYAAYAARGCNGCNCCNGGNAARTTY ACNGTNGCNATHGGNAARGARGGNGGNACNTTYAARGARYTNYTNACNTTYCCNGAYAAY GAYGAYCCNTCNYTNACNYTNTAYACNTAYAAYGTNACNATGCCNCARGARMGNGGNGAR ATGGTNYTNCARTCNGTNTAYTAYACNAAYAAYCCNTCNGCNCCNCCNGCNTTYCAYCAR TGYAGYGAYYTNMGNYTNGTNGCNMGNAAR------------------------------ ------------------------------------------------------------ ------------------------GAYGARAARTGYCCNATGGCNACNGARGAYGCNYTN AARGAYATGAGYYTNGGNCARYTNTCNGAYTAYTTYCAYGGNTAYATHCAYGGNACNCAR GTNYTNTGYMGNMGNMGNGTNMGNATGGGNTCNGTNGAYGAYGGNGGNTGGGAYGTNTGY GARGAYCCNCCNTAYMGNYTNGAYCCNACNAAYTGYYTNGTNTAYTCNTAYGGNATHTCN MGNGAYTAYAGYTTY---GAYGTNGCNATGCARAARTAYGGNTGYGARGTNCAYGCNTAY GAYCCNAGYYTNGGNGAYTAYGAYCCNTCNAARGGNCARAARTTYCAYTTYCAYAARGTN GGNATHGGNGCNMGNAAYTCNAAYGARGARGGNGARTGGACNATHCARACNYTNGGNAAR AGYMGNGARGTNAAYAAYCAYTCNGARMGNMGNYTNGAYATGGTNAARATGGAYGTNGAR GGNTAYGARYTNGAYTCNYTNATGGTNGCNYTNGAYGARGGNAGYYTNCARGAYGTNAAY CARYTNTGYTTYGARATHCAYYTNMGNTCNTCNCCNATHMGNGARAAYYTNYTNTCNGTN YTNAARYTNYTNMGNGGNYTNTGGYTNGARGGNTTYMGNYTNTAYTAYACNAAYMGNAAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNGGNGCN CCNTCNGTNTTYGGNTCNTCNCARGGNCARAGYTCNAGYTTYGGNGCNACNACNAAYACN GCNTCNTCNACNGGNGCNCCNCCNGCNCARCARCARCARCCNGCNCARAGYTCNGTNGCN TTYGGNAAYCCNGGNGCNTTYGGNACNCCNAARCCNCCNAAYGCNAAYCCNTTYGGNGCN ------------------CCNGCNAGYACNCARGCNGCNGGNTTYAAYTTYACNGGNAAY GCNTCNCCNTTYGGNACNTCNGCNAAYAGYACNGCNGCNTCNGGNTTYAAYTTYGGNCAR GCNCARACNGCNTCNACNAAYCCNGCNGGNGGNTTYAAYTTYTCNGCNGCNTTYCARCCN ACNCCNAAYAAYGGNGGNTTYAAYTTY---ACNCCNGGNGGNGTNTCNACNCCNTCNTTY AAYTTYAGYGCNTCNCCNGGNACNCCNAAYATGTTYACNCCNCARAAYCCNGGNGCNGCN CAYMGNCCNMGNGTNGCNGCNMGNMGNGGNACNMGNMGNGGNMGNMGNCARATHTCNCAY ATGATHGCNTTYATHGAYCARGARGCNTCNGARAARGTNGARGARATHGAYYTNAARGCN GARGARGARTTYAAYATHGARAARGGNMGNYTNGTNCARCARTCNMGNGTNCARATHATH GAYTTYTAYGAYAARAARGTNAARAAYGTNGARYTNCARAARAARATHCARAAYTCNAAY ATGCARAAYAAYGCNMGNYTNGARATHYTNMGNAARAARGARGARTAYGTNAARGARGTN YTNGAYGARGCNMGNGARCARYTNAARMGNGTNGCNAARGARAAYCCNGARGARTAYAAR GGNYTNYTNYTNAARYTNATHATGCARGCNYTNGCNMGNYTNATHGARTCNAARGTNACN ATHMGNTGYMGNMGNGARGAYGTNCARATGATHAARAAYGCNGTNCCNAAYYTNGTNAAR CARTAYAARGARYTNYTNAAYGGNAARTAYTCNYTNGARYTNGTNGTNGAYGARGARAAR TTYYTNTCNCARGARATHTGYGGNGGNGTNGARYTNCAYGCNYTNAAYGGNAARATHGTN GTNGTNAAYACNYTNGAYGARMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGCNGARAGYGAYCARCARTAYACNATHTAYGAYGCN---AAYCARTCNYTNACNYTN ACNGTNAGYAAYGTNAAYCARGGNTCNGARGAYGCNCARGCNGTNCARAGYATHCARTAY ATHTCNCCNGARGGNGTNCCNGTNACNCARYTNGAYTCNAGYGAYGTNATHCARGTNGCN CARGCNGCNGAYGGNAGYTTYCARCAR---ACNACNGGNTTYCARAAYYTNCARAGYTCN GTNCARCCNCARATHATHACNAAYGCNGCNTCNGTNCCNATHGTNTCNTCNGCNGCNCAR GGNGGNACNATHYTNCARTCNAAYAAYYTNYTNMGNAAYGTNACNCARCARCARACNCCN CARGCNTCNCARCARCARACNGTNCARGCNGTNGGNACNTCNACNCCNTCNGTNGGNACN AAYGCNGCNGGNATHCCNCARATGYTNTTYYTNAAYCARGTNACNATHAAYGGNCARACN TCNTTYGTNYTNGTNGAYGCNAAYAAYAARCCNATHCARYTNCCNCARGGNATHCARGTN ATHAAYYTNCCNCAYCARCARATGCCNGGNCARTCNATHCARATGCCNGGNGGNGAYACN GGNGAYGARCCNYTNTAYGTNAAYGCNAARCARTAYCAYMGNATHYTNAARMGNMGNCAR GCNMGNGCNAARYTNGARTCNGARGGNAARATHCCNAARGARMGNCARAARTAYYTNTAY GARTCNMGNCAYMGNCAYGCNYTNAAYMGNGCNMGNGGNACNGGNGGNATHTTYGTNGGN CAR------------------GTNYTNGTNGTNGGNAARAAYAARATHCCNGTNAGYYTN AGYGTN---------GARGAYGGNGGNGAYAGYCCNACNYTNCAYCAYYTNTGYCARACN ATHCARYTNCAYACNAAYATHCCNCCNCCNGCNCARAARATHATHTAYMGNGGNMGNACN YTNTTYAARACNTTYGAYCCNGAYGAYCCNAGYYTNAARAARAGYYTNTCNTCNYTNGGN ATHAARAAYGGNGAYMGNATHATGGTNTTYGGNAARCCNTCNGTNGAYGARAARGARAAR GARGGNAGYGAYGCNAARGARGARYTNATG------AARGTNYTNGAYCARCAYCARGCN AARGTNAARGAYATHTGYGTNYTNTGYMGNAAYATGGTNGAYCARATHGGNAAYCCNGGN ACN---ATHGARGAYTGGAARAARCAYAARAARTTYTTYYTNGGNCARTCNGARTAYTCN ATGCARGARYTNACNMGNYTNGAYGCNACNCCNGGNGCNYTNTCNCARTAYGGNGAYTAY AARGCNMGNMGNAARGCNYTNGTNAAYGCNYTNYTNGARAAYATHAGYYTNTGYGAYAAY CARGTNTCNMGNYTNGAYMGNTCNATHCARGARGTNGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNACNAAR GCNATHATHGARAARGAR------GCNYTNGGNATGGCNGTNGCNATGATHAARGGNTCN YTNGAYATHACNCCNYTNGCNATGYTNAGYMGNYTN------------------------ ------------------------------------------GTNTGYGGN--------- ---------------------------------------MGN------------------ ---------------------------ATGGGNAARAARCAYAARTAYGGNAARCAY--- TCNTCNTCNTCNTCNTCNTCNTCNAGYAGYGAYTCNTCNGAYGAYGARTGGMGNCAYYTN CCNAARCAYGARAARAARATGMGNAARAARTGGAARAARCARATGMGNAARGGNCAYATH GCNCAYGGNACNYTNCCNCCNTGGCAYGGNGGNCCNATGTGGGCNCCNCCNATGAARGGN CAYAARGGNGGNAARGGNGCNAARGGNGCNAARCCNACNGGNACNCAYCCNCCNCCNCCN GGNTAYCCNGGNCARCCNGGNTAYCCNGCN---------------CARCCNGGN---TAY CCNGCNCARCCNGGNTAYCCNGCNCARCAYGGN---TAYCCNGGNCARCARCCNGGNGCN TAYCCNGCNCCNCARAAYCCN------AGYTAYCCNCCNCAYCCNGGNGGNTAYCCNGGN GGNCAYGTNCCNGGNGGNTAYCCNGCN---------CCNGGNGGNCARTAYCCN------ ---CCNCCNCCNCCNGCNCARTAYGGNCCNCCNCCNGGNGCNGCNTAYGGNTCNCAYGGN GCNCCNTCNGGNCCNTTYCARGTNCCNCCNGGNAGYGCNTAY------CCNCARTCNGGN TAYCCNCCNCAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNATHMGNAAYGGNYTNATGGCNMGNAARACN YTNGCNMGNMGNGCNAARACNGTNMGNTAYGARAAYMGNMGNMGNTCNTCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYGARAAYGTNTGYGAR TGYTGYGAYAAYTGYTTYAAYGCNTGYTGY------------ACNAAYTCNAGYYTNCAY AARYTNYTNMGNYTNTCNGAYATHTGGTCNTCNATHATGYTNTAYACNGTNATGTCNTTY GTNACNATHGGNGTNGAYGAYATHTTYCCNATGTTYGCNTCNACNATHMGNGAYTAYGGN GGNYTNGGNTTYACNACNAGYGARATHGGNATGGCNYTNGGNTTYGCNACNYTNCCNYTN YTNTTYYTNCARATHAARYTNTAYCCNTTYYTNGTNTCNAARYTNGGNATHMGNAARAAR YTNATHTAYTTYGAYYTNAARGGNMGNGCNCARYTNTCNMGNYTNYTNTTYGCNGTNGCN GGNGTNGARTTYGARGAYTAYMGNGTNCARTGGACNGAYTGGCCNGCNYTNAARCCNACN YTNCCNTTYCARCARYTNCCNGTNYTNGARGTNAAYGGNAARAARTAYGCNCARAGYTTY GCNATHGCNGGNTTYYTNGCNAAYGARTTYGGNTTYTAYGGNAARGAYAAYATGGARMGN TTYGARATHGAYCARATHYTNGARYTNATGAARGAYTTYATHTTYTAYYTNAAYMGNTCN TTYAARGARTCNGAYAARGAYAARAARGCNGARTAYATGAARGARGCNGTNAARGTNCAY AGYYTNACNTAYYTNAAYCAYTTYGARAAYYTNATHAARGGNAGYACNACNGGNTTYTTY GTNGGNTCNAARYTNACNYTNGCNGAYYTNGCNGTNTTYGAYCAYYTNGAYTAYATHACN GARMGNAAYGCNACNGCNYTNGAYAAYTGYCCNCAYYTNCARGCNTTYMGNGARAARATH GGNAGYATHGARAGYGTNMGNACNTTYATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AGYGAYCARCARGAYTCNGTNGAYCCNMGNMGN TCNGARCCNAAYTTYGGNMGNTTYTAYAAYACNAGYTAYYTNGGNYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GAYGAYGCNATGCCNMGNGARATGTCNAAY AAYGGNAGYYTNTCNTTYGCNTTYCAYGTNCCNGGNGARGARGGNMGNYTNTCNTCNYTN CCNTCNCARAARTAYACNGCNAAYGARACNGTNYTNGARTTYYTNYTNGAYAARTAYACN CCNTCNTGGAAYAARTCNMGNTTYGCNYTNGARGCNGTNGCNGTNAGYYTNGGNGCNAGY AARAARATGGAYGTNAARACNATHGARACNATHGAYGAYGARTAYTCNCCNGGNGTNTTY YTNYTNACNAAYTGGYTNACNGAYCCNTCNGAYAAYTCNAARCCNGGNTTY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARGTNYTNGARTTYGTNYTNTCNATHTTYGCNTTYGCN ACNACNACNAGYCCNGARACNTCNACNACNTTYACNGTNCAYAAYTGYTCNTAYTGGACN AAYAAYACNTAYACNGGNTCNGCNTCNMGNACNTTYTCNTAYAGYTAYCCNTAYGAYYTN GARGARACNTGYTTYAARATHCCNATHTGYAARGGNAAYYTNTCNGAY---------GGN GARGTNTGYYTNYTNGARGGNTCNAARTCNGCNGCNCARTTYTAYGTNTTYGTNGGNGTN ATHGTNTTYYTNTAYTGYYTNGCNGCNYTNGTNYTNTAYGTNTTYTAYGAYGARACNTAY MGNMGNAAYTCNMGNATHGTNYTNGCNGAYTTYATHGTNTCNTGYGTNYTNACNYTNTTY TGGATHATHTCNTCNTCNGCNTGGGCNGCNGGNYTNGAYGAYGTNAARYTNTAYACNGAY CCNTAYGAYGGNGGNATHTTY---CARACNGCNGCNGARTGYCARATGAARGGNGCN--- TGYTCNACNACNAARGARGGNAAYTTYGCNAGYYTNAAYGTNTCNATHATHTTYGGNTTY YTNAAYTTYGTNGTNTGGYTNGGNAAYYTNTGGTTYYTNTAYAARGARACNCCNTGGTTY AARGTNCARGCNAARCCNCCNACNCARCCNYTNTCNAARGCNCARYTNGARTGYGARTGG MGNYTNGCNTCNTGYYTNAARAAYGARAAYGARCAYATHCARAARAARYTNAARGARAGY GGNGAYYTNTCNTCNTTYYTNAARGCNTTYATHGARATHGCNGARMGNTGYYTNCARGTN ACNGGNATHCCNGARMGNCCNTGGAAYGAYTAYAAYCARAAYATHYTNAAYCARYTNCAR AAYATHGGNTGGAAYAARGTNACNCAYYTNTCNGARAAYTTYTCNAGYGTNGARATHAGY TGYTAYGAYMGNAGYCAYMGNAAYCAYAARYTNAARGTNAAYTTYAAYAARAARAAYTGY CARGCNMGNCCNGAYTGYATGACNGAYYTNCCNCARGARTTYGAYTTYCAYTGGTCNTCN ACNGCNCARYTNAAYGAYYTNGTNYTNCARTTYGARGGNTGYYTNGGNAAYTAYGARGAR TTYTGGAAYATGGTNGARGARATHGAYMGNAARACNTGGGTNYTNGARCCNGARCAYCCN YTNTAYTCNTGYACNTAYMGNMGNATHGCNYTNGGNCARAAYYTNTCNYTNCAYATHATH ATHAAYCCNYTNCARCCNTCNAGYYTNCCNGARTGYMGNATHYTNGGNTCNGARTCNGCN GTNGCNCCNYTNMGNGARAARYTNAAYGTNAAYYTNCAYYTNTGGGAYYTNGAYMGNTCN YTNYTNAAYAAYYTNCARGARGTNYTNGARATHGAYTTYCCNGCNCCNTCNGAYAARACN AARGARGARYTNAGYGTNGAYTGYGGNATHTGYTAYAGYCAYCAYYTNGGNGARGARATH CCNGAYATHGTNTGYCARTAYCCNCARTGYAGYCARTCNTTYCAYTAYACNTGYYTNTTY GARTGGYTNMGNAAYTCNTCNTGYMGNCARAGYTTYAAYTAYATHTTYGGNGARTGYCCN TTYTGYAGYAARCCNATHMGNGTNAARATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARGARCARYTNAARCARAARCARAARGARATGTAYGCNATGCARGARGARACN TTYGGNAARGAYGARGTNGARGARGARGAYGAYGAYGGNCARCCN--------------- ------------AARGTNCCNMGNAARAGYMGNTTYGAYTCNGAYGAYGARGAY------ ---GARGAYAARAARGARGARGAYGARGAYGARGTNGAYAGYGAYAAYGAY--------- ---------------GTNCCNAARTCNCARCARGARCCNTCNAARTCNTCNCCNAARAAR MGNAGYCCNTCNCCNTCNGAYTTYATGACNGARGARGARMGNGARYTNGCNYTNATGATG AARGTNAARMGNATGYTNACNGARACNYTNYTNGARGTNACNGAYCARGARATHMGNAGY ATHGCNACNGARGTNCAYCARAARGARAARAARAARGCNCARAARGCNCCNGCNAARCAR YTNGCNAARTCNTCNGCNYTNGCNTCNYTNTCNAGYYTNGGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTAYAAYGGNATHGGNYTNCARACN CCNMGNGGNAGYGGNACNAAYGGNTTYGTNCARMGNAAYYTNGCNTTYGTNAARTCNAAR AARGARMGNGTNGAYTAYAARGAYGARGAYGARYTNAARAARYTNGARCARTCNYTNAAY AARCARCCNAAYCARGARATHYTNGAYCAYGARMGNAARMGNAARGTNGARYTNAARTGY ATGGARATGCARGARYTNATGGARGARCARGGNTAYACNAAYAARGARGTNATGGAYAAR GTNAAYATGTTYMGNAARATGYTNATGGCNAARGARGGNGTNTCNGAY---ACNCCNATH GARAARGAYGARCAYGGNMGNCCNATHGCNAARGARACNCAYCARYTNGCNGARGCNAAY CARATHAARAAYGAYAARYTNAARGARGCNTTYGGNYTNTCNGAYTAYACNGAYGGNAGY GCNTTYGAYCCNGAYMGNAARGCNAARGARGARCARGCNMGNGCNYTNGCNYTNGCNCAR AARCARTAYAGYATHGTNAARAGYTCNGAYGARGARGAY------AARGARAGYTCNCCN GTNCCNAARAARAARAARAARAARTCNMGNCAYGAYGAYGGNTCNTCNCCNGARMGNAGY AARGARAARMGNAARAARAGYMGNAARCAYAGYAARMGNGAYMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GTNYTNAAYGCNGCNMGNACNTCN TTYACNAARTAYATHGAYMGNYTNGCNYTNTTYTTYCCNGCNTCNTCNYTNCCNGTNCAY GCNTCNGTNMGNGARMGNACNTCNYTNYTNMGNAARYTNGARMGNCCNYTNTCNCAYCAR YTNMGNAAYATGTCNTTYAAYTCNAARGGNTGYYTNATHTCNTCNCARGARATHATGAGY AGYYTNCARAAYCAYATHYTNGAYYTNACNCARMGNYTNCAYTCNGCNGARAARGARMGN MGNCAYYTNYTNACNGAYYTNAAYGAYYTNAARCARCARATHGGNGAYGARAAYTCNACN YTNCARAAYTCNACNGAYAARCARTCNTCNTGYAARGGNACNAARTAYGTNGCNATGGAY AARTTYGARAARGTNTGYGTNGARYTNTCNGGNGCNYTNMGNMGNGARCARAARGCNCAR GTNYTNYTNCARGARCARAGYAAYCARYTNGCNGARYTNACNTCNMGNYTNGAYATGTGY GCNTCNGARGGNGTNCAYAARGARAARAGYYTNGTNCAYATHCARGARGGNATGACNGAR ATGCARGGNCAYYTNMGNCAYAARGAYCARAAYYTNMGNCARATHAGYAARCARYTNGCN CAYATHGARTAYGARMGNGAYACNYTNCARAGYAAYYTNAAYGAYGCNGARAAYGCNYTN MGNACNGCNTCNMGNGAYAARGARATHYTNGCNCARTAYATHMGNAAYGTNGGNAGYGCN YTNGARACNGCNAARAARCARTTYYTNATHATHAGYGARCCNYTNCCNYTNTCNAAYGAR ATGTCNYTNTCNMGNYTNYTNYTNGAYGCNGAYYTNATHCCNATGGAYATHGGNAARACN GGNCCNGARYTNATHTCNYTNCARAAYYTNGTNGGNGGNTTYGTNGAYGCNCARCAYCAR GCNGTNAAYAARATHMGNTCNYTNGAYGARGARATHGCNTCNCAYMGNAGYCAYATHGAR TCNYTNAARAARGARYTNAGYAAYGCNGTNCARMGNGARTTYAAYCARCARYTNGARTCN GCNACNGAYGGNGCNTAYTCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARGAYATHCCNATHGGN GCNGAYCARATHTCNGAYGARAARCAYCCNGTNAARATHGGNYTNTCNGAYGCNTAYTAY AAYGAYACNATHATHMGNAAYATHGGNYTNMGNMGNMGNACNATHTAYGARTAYCAYCAR GTNATHYTNCARAARAGYYTNGTNMGNACNGGNGCNGTNATHTTYGTNAAYCCNYTNCCN ACNTGYAAYACNYTNGARGAYTGYGARTCNTGYACNAGYCAYACNAAYGTNAAYTTYGAY TGYATGTGGTGYAAYYTNATHGGNMGNTGYTCNGAYGGNYTNGAYTGGTAYMGNCARCAY TGGGAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNAGYYTNYTNTAYGCNGARCCNYTNTAY GGNTGYAARTGYAAYGCNTGYGAYGARGCNATGGGNAGYGAYATHCAYTCNGCNYTNAGY GCNGCNYTNAAYCARGARYTNCARAARTTYCCNATHGGNTCNAAYGTNYTNGTNCARYTN GGNGAYCAYGTNGTNACNAARGGNGARAARACNGGNMGNATHMGNTAYATHGGNCAYYTN GAYAARATHGGNCARCCNAAYATGGTNTTYGTNGGNYTNGARYTNGAYGCNCCNGTNGGN CAYCAYGAYGGNTTYTTYAAYAAYAARMGNTAYTTYTTYTGYCARAARGAYCAYGGNATH TTYGTNCCNYTNCAYGAYGTNATGTGYAARGTNTGYCARAARAAYGARAGYTGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GARTGGGAYGAYYTNGCNAARTAYTGGACNAGYAAYTCNGTNAARAAR CCNGCNTGYATGAARCAYYTNYTNAAYAARAAYGTNAARATGTTYAAYYTNTAYTGYCCN ATGAGYGGNATHGAYCARGARGTNTGYTAYGCNYTNTTYAARATGTTYGGNTGGCCNATG ATH--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MGNGCNGARATHTCNTCNTGGYTN GCNAARGTNATHAARAAYGARCCNATHCCNGAYTTYGARATGAAYGCNCARACNATHCAR YTNYTNCAYGGNYTNTCNGTNATHAGYCARTGYAAYGARAARAAYACNCARYTNTAYATH GARGAYATHAARAARAARATGGAYGARTAYAAYGCNGAYGCNCARMGNATHGGNAAYGTN YTNGAYMGNYTNACNYTNGGNCARAAYAGYYTNTCNMGNTCNGGNTCNTCNTGYYTNCAR GCNYTNGCNMGNACNGGNGCNTCNYTNGGNGTNAARGAYGCNTCNGAYTCNTGYTAYYTN YTNTCNATHCARGARYTNCAYYTNAGYGTNAAYGARYTNACNGARAARYTNCAYTCNGAR AAYCARGAYYTNCARACNATGYTNMGNAARACNCARAAYGTNYTNATGAARCAYAGYTCN YTNAARAARGCNYTNGARGTNYTNGAYGARMGNTCNTCNCARGARGCNGCNMGNATHGCN GARMGNAARAARGARACNGGNATHGTNAARAARGCNACNGCNGARAAYGAYACNAAYATH GARAARYTNAARACNAARYTNGCNCARTCNGGNYTNAGYGARTCNGAYTTYCAYGAYAAR YTNGTNAARAARAARGARAARYTNAAYGCNGTNGARAAYGARYTNGCNCCNYTNAARGAR GARYTNCARTCNTTYACNAGYYTNCCNCCNGAYGCNATHGARGCNAARGTNCARATHGAR CARYTNAARMGNGARYTNAGYMGNYTNCARACNCARATGTCNGARTGYGTNGAYGTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TTYAAR GTNCCNACNTCNATHACNGGNMGNGCNACNATHCCNGAYCCNGCNMGNCCNTCNGARYTN MGNGTNTCNTTYTCNMGNTTYGAYACNTCNACNGGN---GGNCCNAAYTAYTTYATHGTN GARACNGAYTAYACNACNTAYACNGTNGTNTTYTCNTGYACNGAYYTNCCNGGN---GAY TTYAGYATHCARAAYGTNTGGATHYTNACNMGNGAYMGNGGNGTNGCNCCNTCNAAYYTN GCNAAYATHAARTCNACNYTNCARTCNAARGGNGTNGAYGTNACNAARTTYAAYTCNGTN GAYCARTCNGAYTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNATHMGNMGNGTNGTNGGNGGNCARCCN GTNTCNMGNGGNACNTGGCCNTGGYTNGTNTCNYTNAAYTAYCARGARCAYCAYCCNTAY YTNGARYTNCARGGNYTNGAYCAYYTNTGYGGNGGNACNYTNATHGAYCCNAAYTGGGTN YTNACNGTNGCNCAYTGYGTNCAYCCNYTNYTNGGNAAY---GGNYTNGGNGTNCCNTCN AAYTGGATHGCNGTNYTNGGNGARTAYCAYMGNMGNGTNGARGARTCNTCNGARCARMGN YTNCCNGTNGARGCNATHTAYATHAGYCCNAARTTYTCNTGGAAYCCNAARTTYACNGGN GAYYTNGCNYTNYTNAARYTNAGYCARCCNGCNATHYTNAAYAGYGAYGTNMGNCCNATH GCNYTNGAYGAYGGNATGTTYATHCCNGAYGGNGCNGARTGYGAYGCNGCNGGNTGGGGN CARCAYGCNGARGCNGGNTCNCCNGAYCCNCARTTYGGNAAYGGNACNATGGTNCCNCAY TTYGTNACNYTNAARAARCARGAYCARGGNACNTGYAARGCNCARTAYMGNTCNACNTTY TTYGGNATHGAYGCNACNGTNATGTGYTTYTCNTCNGAYGARMGNAARGAYACNTGYCAR GGNGAYTCNGGNGGNCCNYTNGTNTGYYTNAAYCCNYTNGGNATHGGNGTNYTNTCNGGN GTNGTNTCNGCNGGNCCNGGNTGYGGNMGNGARAAYTTYTCNGGNYTNTAYACNMGNGTN TCNAGYTAYTAYCCNTGGATHCARCARACNATGGCNTCNCAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHTGYAGYMGNCARAAYCCNTCNMGNGTNATHATHCARGGNYTNGAY AGYGCNGGNAARACNACNYTNYTNTAYMGNYTNAARYTNGGNGARGTNGTNACNACNATH CCNACNATHGGNTTYAAYGTNGARACNATHGARACNAGYMGNGGNYTNGARATHACNGCN TGGGAYYTNGGNGGNMGNGAYAARATHMGNCCNYTNTAYMGNCAYTAYTAYGGNGGNACN GARGGNTTYATHTAYATHGTNGAYAGYGCNGAYGTNGARMGNYTNGARGARGCNYTNACN GARYTNCAYGAYATGATHYTNCAYGARGAYYTNTCNMGNAAYTCNGTNGTNATGYTNYTN GCNAAYAARCARGAYYTNGARCAYGCNYTNAGYCCNGCNAARATHGARGCNMGNTTYCAY GCNAARTGYAAYYTNGARYTNTAYGTNTCNYTNTTYGTNATGCCNTGYAGYGTNACNTCN YTNGAYGAYAARCCNATGTGGCAYGCNTTYAAYTAYTTYGCNAARATGATHAARYTNAAR AARGARGGNMGNYTNGARAAYGGNYTNATHAARACNGCNAGYCARGARGCNGARAGYGAR AARATGGAYGAYGTNGGNYTNTTYCAYAARYTNAARAGYTCNGTNAARAAYCCNYTNCAR YTNGTNAARTCNYTNYTNTTYTAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AGYGGNYTNATH GGNMGNAGYTTYACNATGYTNTTYGCNAGYGCNGGNTAYGAYGTNACNATHTTYGAYYTN GAYCCNAARCARACNTCNGCNGCNAARGCNGAYATHMGNATHCARYTNGCNAAYYTNGAR AGYCARGGNYTNYTNMGNGGNAARTTYTCNAARGARGARCARTTYAAYAARATHTCNACN ACNGARAGYYTNGARGARTGYGTNAARGGNGCNTTYTTYATHCARGARTGYGTNCCNGAR AARYTNGARATHAARMGNTCNYTNTGGTCNAARGTNGAYAARYTNGTNGAYGGNAARGTN ATHATGTCNTCNTCNACNAGYGCNYTNYTNCCNTCNGCNATHTCNGAYGGNYTNGAYCAY AARAAYMGNTTYATHGTNTCNCAYCCNTGYAAYCCNCCNTAYTAYGCNCCNGCNACNGAR GTNGTNCCNGCNAARTGGACNGAYAARGARGTNACNACNMGNACNATHGARGTNYTNAAR GARGTNGGNCARGTNCCNGTNYTNATHAARAARGARATHGAYGGNTTYGTNYTNAAYMGN YTNCARTAYGCNATHATGGGNGARGCNTAYAARYTNGTNAARGAYGGNGTNGTNAGYGCN AAYGAYYTNGAYGTNATHATGTCNCARGGNYTNGGNATGMGNTAYGCNTTYATGGGNCCN TGGGARACNGCNCAYYTNAAYGCNGARGGNATGYTNGTNTAYGGNGARMGNTAYGCNGAY ATGATHYTNGGNATHCARAARAGYTTYACNTCNCCNYTNMGNATGGARGGNGARACNYTN CARGTNATHCAYGARGAYATGYTNACNATHGCNGGNCCNYTNGARGAYATGCARGCNMGN MGNCARTGGMGNGAYMGNMGNYTNGTNGGNYTNGCNCARYTNAARGCNAARATGGAYAAR GARGAYGCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TCNTCNTCNTCNTCNTCNGCNGCNACNCARGAY AGYTCNTCNTCNCARTGYGCNATHTGYYTNTCNGARTAYAAYGTNGGNGAYTCNAARMGN ATHYTNCCNTGYCARCAYGAYYTNCAYAARGARTGYATHGAYCARTGGYTNAARACNAAY GCNACNTGYCCNATHTGYMGNAARGAYATHMGNTAYAARCARCAYGCNMGNGCNAGYATG YTNAAYGAYTAYYTNGTNTTYAARGCNGAYTAYYTNACNAARACNYTNGARGARCAYAAY TTYCAYTAYTAYYTNGCNTCNAARAARGTNTAYGAYATHYTNGTNAARACNCCNGTNGTN GARMGNMGNYTNCAYMGNMGNTTYATGAARACNMGNMGNAARAARYTNCCNGTNCCNACN GARAAYGAYGARTAYTTYTTYCAYGARCAYTGGTTYGCNCAYAAYGARYTNAARATHGAR GAYTAYAARAARGARAARGARGCNGARMGNCARGCNAARGTNGARGARGCNMGNGARAAR GGNGARYTNTAYGARTGYTGYTGYTGYTAYGARGAYGARTGYYTNTTYGARGAYYTNACN AAYTGYCCNGARGGNCAYYTNTTYTGYAARGTNTGYGTNGTNMGNTCNACNGARGCNGCN TTYGGNGARATGAARACNMGNTTYCCNTGYYTNACNGGNGARTGYGAYCARGARATHCCN YTNAGYACNYTNCARGGNATHGTNCCNCCNAAYTTYTTYTCNAARATHGTNAGYMGNYTN CARGARGARGARGTNYTNCARGCNCARATHCCNGAYYTNGTNACNTGYCCNTTYTGYCCN TTYGCNACNATHATGCCNGAYCCNGAYGAYAARGTNYTNMGNTGYYTNAAYCCNGARTGY YTNAARGARTCNTGYMGNYTNTGYCARGARGARAGYCAYATHCCNYTNAARTGYAGYGAR GTNGARAGYMGNGCNGGNACNAAYATGMGNACNTTYATHGARAAYAARGTNGCNGARGCN GTNATGMGNAARTGYCAYAARTGYGGNAARMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNACNTGGTGYMGNAAYGTNACNTTYACNAARGCNYTNMGNCAR GARGAYCARGAYAARCCNGARGAYACNGAYGAYGGNAGYACNCCNAARMGNAARGTNGTN GAYGTNGARACNAGYATHMGNTAYYTNAAYAGYAARGCNTTYGAYGCNGGNTAYGGNGAY AARCCNGTNTGGTTYCAYTAYMGNMGNAAYTTYAARAARAAYATHATGCCNCCNACNMGN AARGAYTGYATHMGNATGGGNAARATHTCNACNGCNAGYCCNTGYCCNGTNTGYMGNGAY GARTAYYTNGTNYTNGAYGCNAARAAYGTNAARYTNYTNGARCARTTYATHTCNCCNTAY ACNGGNGARATHTTYGAYTCNATGAARACNGGNYTNTGYCARAARCARCARMGNAARYTN ACNGTNGARGTNATGMGNGCNTGGGAYCARGGNTAYYTNGARATGAARGTNCCNTTYMGN ACNTAYGAYTAYAGYGAYTAYAARAGY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GTNAARYTNCCNYTNAARGTNGAYATHATHAARCAY CCNAARGARYTNGAYGGNAARAGYACNGCNCCNCAYGCNTCNATHYTNGCNCCNGAYGAY GTNACNATHCAYACNTAYCCNTGYGTNCCNGAYTAYAAYCAYCARAARGTNATHGTNGTN TTYCCNGGNGARGAYGCNGTNAGYYTNGAYGARYTNGGNACNACNACNACNAGYACNGAR AAYCARAAYCARTCNGCNCCNGCNTCNAARGAYGCNAARGARGARATHGAYCAYCCNACN AAYGGNTCNTGYGAYGCNGGNGTNMGNGARGGNAAYGTNAARCAYGAYGCNACNAAYAAY ACNCCNTCNMGNTGYAAYAAYGTNTCNCCNGCNTCNGARGCNAARGGNYTNTCNTGYGAY GCNACNCCNAARACNAAYTCNGAYTCNGAYTCNCAYMGNGAYTCNAARATGAARMGNACN YTNAAYAAYGARGAYGGNAAYGGNAGYGTNCCNGGNGAYAGYGARTGYGARGARTCNGGN CCNTTYGTNGTNAARCAYCARMGNACNTGYYTNMGNCARTGYCCNTTYGAYAARGTNGTN TTYGTNGAYTGYACNTGGAAYCARACNAARCARATHGTNACNGAYGARMGNYTNAARGGN YTNMGNAARGTNGARYTNAARTCNCARTTYACNAAYTTYTGGMGNACNCARGARGGNATG CCNAARACNTAYYTNTCNACNATHGARGCNATHTAYTTYTTYYTNMGNGAYTTYCAYACN ATHTTYGTNGAYCCNGTNTAYMGNCAYCARTAYGAYAAYYTNYTNATHTTYTTYTGYTTY ATGTAYCAYAARATHAARCARAGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GTNTAY AGYACNAGYATHTTYTGGATHTTYTAYGCNYTNATHCAYATGTTYATHACNTTYTTYYTN TCNGCNCARYTNTAYTTYATGGGNMGNTGGMGNATHGGNTGGTGGTTYTTYAARTGGTTY ACNYTNTTYYTNATHAAYGAYTGYMGNMGNTGYTCNCCNCCNGTNAGYCCNAGYMGNTTY ATHATGYTNATHATHGGNAAYATHATHAAYTGGACNTTYGCNYTNTAYGGNGCNATHACN MGNCCNTCNGAYTTYGCNAGYTAYYTNYTNGCNATHTTYATHGGNAAYYTNYTNYTNTAY TGYATGTTYTAYGTNATHATGAARYTNYTNAGYGGNGARMGNATHAGYYTNYTNGTNATH GGNGTNATGGTNACNTCNYTNGTNTCNTGGGGNTGYTCNYTNTAYTTYTTYTTYCARCAY GTNACNTCNTGGCARAARACNCCNTCNGGNTCNMGNGARGGNAAYMGNGARTGYATHYTN YTNGAYTTYTAYGAYTCNCAYGAYGTNTGGCAYTTYYTNTCNGCNTTYAGYYTNTTYTTY ------------------------------------------------------------ ---------GAYTCNMGNGCNGARGGNGCNGGNGCNATHCCNGTNCCNATGGARGARCCN ---------MGNACNGAYGGNMGNAGYAGYGTNGARGTNAARGARAAYGGNGARTAYMGN GGNGARGAYMGNACNGAYGCNTCNCCNCCNGARGGNACNGARGAYAGYMGNGGNCARGGN CARTGGAARTCNCCNGARGAYCARTAYATGGCNTCNGCNGTNYTNGCNCARAARACNGAR ---------------------CARGARGCNYTNAARGARGTNCARGARGARMGNGAYMGN YTNYTNGARGARCARGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TAYACNGCNTTYTAYACNGCNYTNACNAARTTYACNGCNGARATH CCNAARMGNATHAARTCNTCNGCNCCNAARGCNGTNTCNTCNAAYATHGCNGCNYTNACN AARATHYTNCCNCCNGAYGAYAARGCNTTYACNYTNCAYTAYATHGCNGCNATHAARAAR MGNGCNACNYTNACNTTYAAYGTNYTNGCNAARTAYYTNGARYTNGGNTGYAAYTAYGTN AARGARGAYCCNMGNGAYTGGTTYAAYATHCARAGYYTNTCNYTN---------GGNTTY TCNATHGCNGTNAAYMGNATGTCNATHAARAARYTNGTNGARTCNGAYGTNGAYGTNGTN GGNCCNGGNATHGGNGGN------------------------------------------ ------------------------------CARYTNTCNACNTTYAARAGYGAYYTNAGY YTNGARAARATGTAYCCNAAYTCNGAYATGGAYTAYYTNMGNAARAAR------CARCAY GAYGGNGARATGGAYATGGARAARTTYTCNGGNTAYATHCCNGTNGARCARYTNGARATH AGYCAYAGYMGNAGYAGYGGNCCNGGNGGNCARAAYGTNAAYAARGTNAAYAGYAARGTN GARGTNMGNTTYCAYYTNGAYTCNGCNTCNTGGATHCCNCARTGGATHAARYTNAARYTN ACNGARCARGARCARAAYMGNATHACNAARGAYGGNTTYYTNATHATHMGNTCNGAYATG ACNMGNAARCARYTNYTNAAYCARGCNGAYTGYYTNAAYAARYTNMGNAAYATGATHTAY CARGCNTCNGTNYTNCCNGARGARCCNACNGARGARGARATHAARAARAARGARCARMGN ATGATGAARGCNAARGCNGGNATHYTNMGNGARAARAARAAYMGNTCNYTNYTNAARAAR TCNMGNTCNAAYCCNGARYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNMGNCARGAYACNGTNCARAARYTNGTNGAYGCNAARGCN GTNTCNGTNYTNTTYAARTCNYTNAGYATHTCNAAYYTNAARTAYTGYGARGCNGTNYTN MGNTGYYTNMGNTCNATHTTYATHGARAAYACNGAYTGYATHGAYATHYTNTAYGARGAR AAYAGYTTYGGNCCNTCNTAYATHCCNACNYTNYTNGTNATGACNCARCARTCNYTNGTN TGYCARGARTGYGTNACNAAYATHYTNGTNTGYTGYTGYAARACNMGNGARCAYCARATG TCNYTNYTNAAYAGYCARGCNYTNCCNATHYTNTCNCCNYTNYTNCARTCNAAY---CAR TAYAARATHCARATGCCNACNYTNMGNTTYTTYGCNAARGTNTGYCAYAARAAYYTNGAR GTNTGYACNGAYATHGCNAARGAYAAYAARYTNGTNGARACNTTYGTNGGNYTNATGAGY TGGGAYAARTCNACNGARATGCARYTNTCNGCNGCNGARATGYTNACNAAYATGCAYMGN TCNGGNGTNATHGCNGCNAGYGAYTTYATHATHAGYMGNAARACNYTNGGNACNYTNGTN MGNATGTGYATGMGNGAYMGNAGYGTNGARGARAAYGTNMGNGGNGCNGARATHYTNGCN TAYYTNATHGARATHGAYCCNGAYYTNCARYTNATHGCNAGYTAYACNTTYCAYYTNATH GARGCNYTNGCNAGYTGYYTNMGNTAYCARGARACNAARATHACNTCNTCNGARGGNAAY AARGAYGTNGAYTGGGGNAGYGARATGMGNMGNGCNGCNTTYYTNGCNTTYGCNTCNATH AGYGCNAAYGAYGARGARGTNMGNGCNAARGTNATHAARAARGAYGGNGTNATHAARCAR ATHCARACNTCNYTNACNAGYAGYAGYGAYGGNGARGTNGCNGCNAGYYTNMGNTGYYTN CARTCNYTNACNMGNTCNGTNCARCARATHMGNACNGARYTNCAYGAYAAYGCNGTNTGG AARCCNYTNYTNGARAARGTNMGNTCNGGNAAYAARGARATHATG--------------- ATHYTNGCNATGTCNTGYYTNTGYAAYYTNGTNYTNGARTTYTCNCCNAGYAARGARGCN YTNGTNGARAAYCAYGCNGTNGAYGTNYTNTGYAGYYTNTCNMGNAAYGAYGAYAAYATH GTNMGNYTNAAYGCNACNTGGGGNATHATGTCNATGTCNTAYTGYGCNTCNGARGAYYTN MGNACNAAYATHATHAAYAARYTNGGNACNACNACNYTNGTNMGNMGNATHCARGAYCCN GTNYTNYTNATHMGNGARAARGCNYTNTGYATHGTNMGNAAYYTNYTNGCNGGNAARATG ACNATHGAYAGYACNGTNAARCARYTNGGNAAYGARGTNATHGARGCNGTNTTYAARACN YTNTCNGAYCAYGAYATGCCNTCNAGYATHATHACNCARGCNYTNTGYGCNYTNAGYAAY ATGGCNGAYGGNCCNTCNTGYAARGCNTAYATGATHGCNAARACNGAYGARATHAAYGCN GTNGTNAARTAYYTNCARTAYCCNGAYAARGAYYTNCARYTNCCNGCNATHCARTTYGTN AGYAAYYTNGTNGAYACNAGYGAYGAY------------------------GGNTCNTAY CARMGNATGYTNCARYTNAARACNYTNGGNGTNCARACNYTNYTNGARAGYYTNATHGGN ACNGGNYTNGARGARGTNGARYTNMGNGCNCARCARGCNYTNAARTAYTTYGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNCCNGTNYTNCARCARCARYTNGAYGCNYTNYTNGAR TTYGAYTGYACNCCNAAYGARYTNACNAAYGGNGTNATHACNGCNTGYTTYATGYTNYTN TTYAARGAYYTNATHMGNYTNTTYGCNTGYTAYAAYGAYGGNATHATHAAYYTNYTNGAR AARTAYTTYGAYATGAAYAARAARCARTGYAARGAYGCNYTNGAYYTNTAYAARMGNTTY YTNGTNMGNATGGAYAARGTNTCNGARTTYYTNAARGTNGCNGARAAYATGGGNATHGAY AARGGNGAYATHCCNGAYYTNGCNAARGCNCCNGCNAGYYTNYTNGAYGCNYTNGARCAR CAYYTNGCNTCNYTNGARGGNAARAARTCN---GCNACNACNCCNACNGGNTCNAGYAAR CCNTCNGGNTTYACNACNGCNYTNAAYAAYATGTCNAGYAAYACNTTYAAYGTNAGYGAR GCNGARAARAARMGNATHYTNGARGARGARAAYCARCARYTNCARMGNCAYAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGGCNGGNMGNCCNAARTCNGGNATHACNGCNGGNACNGAYGTN AAYYTNGAYTTYYTNTCNAARGARGARAARGARGCNYTNYTNTCNAARAARATGGAYATH ATHMGNCARCARAAYAARATGATHAGYGARMGNCAYGARYTNATHGARGCNGAYMGNMGN AARGCNGARGARTCNGGNAAYGCNGTNAARGCNATGGAYAGYAARACNYTNCCNGCNGAR GGNGCNCCN---ATHAARCCNMGNGGNMGNGGNMGNGGNCARAGYCARGGNCARGGNTCN CAYMGNGAYGCNCARMGNCCNAGYAARGAYMGNCCNMGNTCNCAYGGNGAYACNTCNTCN TAYGARCCNATHGTNGAYGTNAGYGAYTTYACNGTNCAYMGNAGYMGNAAYAAYAAYMGN GGNAGYAAYAARGGNGGNCARCARCARTAYCAYCARCAYTAYCAYCAYCARGAYMGNGAY GTNCCNACNTCNACNCCNAARAAYMGNMGNAARCCNCAYCAYCARAAR------------ ------------------------------------------------------------ ---------------------------CAYCARAARGAYGARGGNTAYAAYGCN------ ------------------------------GGNGGNCAYGCNMGNTCNAAYMGNMGNTCN GAYCCNCCNGAYAAYMGNGGNAAR---------------TCNAARCCN---TAYGAYGGN MGNYTNAARGARNNNNNNAAYCCNCCNCCNGAYCCNACNTTYAAYCCNYTNGCNGAYTGG MGNMGN---------------GARMGNGGNTCN------------GAYGAYMGNTCNGAY CAYAARMGNCAYCCNMGNAAYTAYGGNGGNGGNGCNGAYYTNGCNAARGTNAARGAYAAY ATGAARACNATGMGNGARMGNGARAARGARMGNCCNGTNTCNTCNMGNAAYYTNGARATH GTNATGACNGGNMGNGARMGNAARAAYCAYGARCARTGGAARCARGARMGNGARMGNTAY GAYAAYGARMGNATHCARMGNCARATGGGNGAYACNGGNTCNTGGAARMGNGARTGGGAY CAYGAYAARGTNGTNATGGARTAYGAYGAY------CAYCAYCAYAAYMGNATGGARCCN GCNAARMGNCCNGCNGGNMGNATHGGNAGYGGNMGNTTYGAYMGNGGNGAYMGNGARGAY MGNCCNAARGCNGTNGTNMGNGAYGGNAARGGNGGN------------------------ ---------------------------------------------------------TCN TCNCCNCARGTNCARTCNCARCARAGYCAYCAYCAYCAYCAYCAYCARGCNCCNCCNCCN TCNCAYCAYCARCARACNCCNYTNAGYCCNCARGGNMGNGGNMGNGGNMGNGGNMGNGGN GTNGGNCARGTNCARGGNCCNGGNCARAGYCCNGGNGGN---GARAARTCNCARMGNCCN MGNACNTGGTCNGGNGGNGAYGAYMGNTTYGTNGARTGYCARAARGARATGYTNGTNGTN AARTTYGAYAAYACNGTNGGNGAYAAYTCNGTNGARGTNGARTAYGAYGAYGARGCNCCN YTNTCNCCNACNYTNTCNTCNAARTCNTCNGGNTCNACNCCNGGNMGNGGNCCNACNGGN MGNACNCCNAAYCARAGYGGNGGNAAYAGYAGYGGNGGNGGNGCNTCNAARTCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNACNGCNTCNAARCAYCCNCAYGGNACNAGYCCNACNACN GGNAGYCAYCCNCAYACNGGNCARGCNMGNCCNYTNTTYTAYGGNAAYGAYAAYAGYAGY GTNAAYMGNCARTCNMGNACNCARACNACNMGNCCNGAYCCNATHCCNNNNCARCCNTAY GCNGGNGCNCCNGCNCARMGNGTNGGNAGYGCNCCNYTNMGNAARATG---ACNAAYCAR GGNACNATHMGNACNGGNCCNGGNAAYMGNTCNAAYAARACNYTNGARCCNGGNGARACN ---------AGYGAYACNCCNAGYCCNTTYATGMGNCCNCAYTCNMGNTTYGAYTCNGGN YTNGARCARGTNCARTCNCARCAYCAYCCNAAYTTYYTNCCNCCNATGCCNMGNCCNCCN CARGCNTCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGAGYACN TCNGTNAGYACNATGMGNGCNGGNGCNACNAARYTNCCNGGNCCNAAYGARAARACNGCN AARGGNGAYATGATHGCNTCNTCNCARTCNGGNACNGCNGCNAARACNGAYGGNCAYTCN AARAARATGCARCCNACNCARGARCARYTNMGNYTNGCNCARATGATGAGYATHAAYCAR ACNGAYGCNGAYCCNAAYACNGTNMGNCARYTNATGGAYATGACNGGNAARAGYGARGAY GARGTNGTNATHGCNYTNCAYGAYGCNGGNAAYGAYGTNGARMGNGCNGTNATGTCNYTN YTNGARGGNGGNGARGARCARGAYGARTGGMGNGARTGYGGN------AARAARAARAAR AARAGYACNCARAARGARAAYACNAAY------AGYGARGAYCAYTCNGARGGNMGNAAY MGNGAYMGNGGN---------------------------GAYAAYCARGAYYTNCCNCCN MGNMGNGGNMGNMGNAAYGGNGTNCCNCCNCCNMGNYTNGCNMGNGGNMGNGGNMGNGAY MGNGGNAAYTTYGGNGAYMGNGAYMGNGARMGNAAYAAYGCNTCNGCNGARGAYTGGGAY AAYGAYAARGARGAY------------------MGNGGNCCNMGNGGNGAYMGNGGNGAY MGNGGNMGNTTYMGNGGNMGNGGNGGNTTYAGYGGNMGNMGNCCNGCNGGNGCNYTNAGY GGNGGNMGNGGNGGNMGNTTYAAYAAY------GAYMGNGAYAAYMGNGGNTTYAAYMGN CCNMGNMGNTTYGARAARATGAAYAAYTCNCARCCNYTNGAYGGNCCNGARCCNGARATH GAYACNTGGACNAAYGARACNGCNGARACNAAR---TCNAAYAARGAYACNGAYTGGAAY AGYTGGAAYGAYTCNTGGGTNAAYGARGARGAYCARTGGACNGGNACNYTNGARGARACN AARGTNTTYACNCCNTCNCAYGTNAARATGCCNGARGCNGARCCNGTNAGYAAYGARCCN CCNAGYTCNYTNGGNCARMGNYTNGAYGTNGGNAGYYTNTTYGARAAYGCNAARTTYACN AARGCNCCNGAYTAYAGYAARCCNAGYGGNGAYTCNTAYATHAAYCARTTYAAYCARGCN GCNACNGARTCNATHAARAAYACNATHGGNATHGGNAAYACNGCNMGNCCNCARATHCCN YTNTCN---------------CCNCCNGAYACNTCNGGNTCNYTNGGNYTNTCNAAYYTN GCNCARAARACNGCNCARGGNCARGGN---TCNGTNYTNCCNTCNYTNCARCCNTCNGCN CCNCARAAY------TCNYTNCCNCAYGCNATGGTNCARYTNTCNCARATHTCNCAR--- ------------------------------------CCNGTNTCNCARCARTCN------ TCNGGNATGTCNCARATG---------GGNATGGGNTCNCCNCCNTCNGCNTCNGCNAAY CARGCN---CCNCARCARTCNMGNATHCCNGCNGTNGTNCARCARAGYATGCCNCARACN AGY---------------------------ATHAAYAAYATGCCNCARMGNCCNAARACN CARMGNTCNAARYTNCCNCCNCCNTCNAARATHCCNTCNACNGCNGTNGARATGCCNGGN CAYATHCCNMGNAAYCCNCARYTNGAYGTNCARTTYGGNYTNGAYTTYGGNTCNGARCCN TCNGTNCARTTYGGNTTYGGNGGNAGYGGNGAYAGYACNGCNGTNACNAGYTCNTAYTCN ACNACNACNAAYGGN---ACNCCNGCNATHTCNAAYCAYYTNAAYCARGGNCAYATGACN CARTCNGCNGGNGAYGGNAAYTCNGTNAGYCCNATHATGCCNTCNCCNTCNGCNGGNTCN GCNAAYGTNCCNTCNGCNATHGARTCNCARGGNCCNAAYMGN---CARGGNGTNTTYCAY AAYTCNATGTAYCCNTCNACNCARCARCARACNGARAGYCARGCNYTNGARATHGAYCAR AAYAARGTNAAYGAYTCNATHCCNTTYYTNTCNTCNCARYTNGARMGNAARTCNAGYCCN ATGGCNTCN---CARMGNCARGGNCARACNAAYCARAAYYTNACNTCNGGN------CCN TCNAGYAARAGYGAYTCNACNAGYGCNGTNGCNAAYAAYAGYTAYTCNGCNGCNAAYGGN TAY---CCNTCNTCNTAYCARAGYCAYTCNAARGGNTCNTCNATHTCN------CAYACN GCNACNTCNCARCCNTCNCARACNTCNTCNTAYCAYGGNCCNTAYCCNGTNAAYCCNTCN TCNTAYCCNTCNACNGGNCARACNCCNTTYCCNGCNCCNCCNAAYGCNGCNCCNTTY--- CCNTCNGCNCARCCNTCNCARTTYAGYTCNTCNAAYTCN------TCNCARAAYCARTTY TCNTCNGGNCARAAYCARTAYTCNGTNGGNACNTCNACNYTNTCNCAY------CARAAY AAYCARTTYCCNTCNAGYGGNCARAAYAAYTAYGGNAGY---GGNTCNTCNCARTAYTCN GGNTAYCARAAYAAYAGYTCNTTYCCNCCNCAYCCNCARTCNCARACNAAYTTYCCNTCN ACNCARAAYGGNGGNACNGGNGCNGTNYTNTAYCCNGCNTCNACNCARTCNGGNGTNGCN TCNTAYACNACNCARTCNAGYTCNTAYCARTCNCCNTCNGCNGGNTCNTAYCAYTCNTCN MGNGAYTCNGCNACNAAYATGGCNGTNAGYACNCARTCNACNAGYGGNATGACNTTYCCN AGYCARCCNCARAAYTCNAAYATGAARCCNGTNACNACNCARAGYAAYTCNAGYTAYAAY TCNCARAGYTAYACNGCN---CCNACNCCNYTNCARCCNTCNTCNYTNGCNAAYAARYTN GGNGARAGYYTNTCNAARATHTCNATGAARGAYTCNTCNTCNGTNYTNGAYAAYCAYCAR TCNGCNCARTAYGARCAYAAYCCNTCNCCNGCNAGYGTNCCNACNAGYGTNAGYYTNCCN TCNGCNTCNAGYTCNTCNTCNYTNTCNACNGGNACNAAYGCNYTNTCNTCNGCNTCNACN GTNACNTCNGTNTCNCCNGCNTCNMGNGTNGCNTCNATGCCNTCNGCNTCNGGNAARGCN CCNCCNAAYATHCCNCCNGGNGTNCCNYTNATGGGNCARTAYATHATGGGNCARAGYACN ATHCCNCCNTTYTAYAGYGTNCARCCNCCNYTNTAYGGNTAYGARGAYGTNCARYTNYTN CARCARMGNATGCCNATGCARACNGGNAGYTTYTAYGAYATGGGNGCNTTYCCNGCNGCN CCNGCNGGNTCNACNYTNCCNACNGGNMGNGAYCCNCARCCNCCNATHCCNAAYGTNCCN TTYTCNGGNACNTCNGAYACNAARYTNGCNMGNGTNGAYGCNCARAGYCCNAAYGCNTCN AGYCARCCNCARAGYGCNCAYTCNGCNACNCARCARCCNYTNYTNAAYTTYCAYTAYGGN TAYTAYTAYCCNTCNATGTTYCCNGGNGCNGCNGGNYTNCARTAYCCNACNACNGTNTAY CCNATHCCNCCNGTNACNAAYGCNGCNGCNCAYCARGGNACNACNGCNACNACNCARTTY CARAARACNTTYCCNTCNCAYGTNTAYACNACNAARGGNTAYGARGARGTNAAYCARGTN CARGAYTTYTCNAARACNGGNTAYGGNAGYTCNCARAGYTGYGGNAARGCNTCNGGNACN MGNATGTCNACNMGNTCNGGNACNAGYGARATGACNCCNAAYGCNTAYAGYAARTCNCAY GGNCARGCNGGNTAYGAYAARCARGGNTAYCAYGGNGGNACNCCNCCNCCNTTYAAYYTN CCNYTNGCNTCNGGNACNCARACNGGNCCNATGGGNGCNCCNACNACNCCNTAYGGNGCN CCNTTYYTNCCNGTNATGGCNGCNCAYCARCCNCAYTCNCARATGATGCAYCAYCCNATH CARCARGAYAAYAAYACNACNAGYTCNMGNGGNYTNAAYCCNGCNGGNGGNCARGGNAAR TCNGGNGCNGCNAARTCNTTYGGN------CCNCCNTAYTGGAAYAAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGGNGTNYTNGAY ATGYTNAAYCCNGCNYTNGTNYTNAARYTNMGNYTNGTNGTNTAYGGNATHYTNATHTTY TTYTCNTTYTTYATHTTYGTNGGNACNGCN------------------------GTNATG TGYCCNYTNTAYTTYGAYTAYAGYAARAARGGNTAYGAYTCNGGNCCNGAYTCNAAYTGY GGNTAYCCNATGGCNATHTCNATHATGTTYCARYTNYTNTAYYTNYTNTTYMGNATHGGN ACNYTNGTNYTNGTNYTNYTNGGNAARTTYACNGCNGAYATGGTNYTNTTYTCNGAYYTN GCNGARTTYGTNTAYGTNGTNGTNGAYYTNTCNGCNTTYTTYYTNATHTTYATHGCNGCN TGYATHYTNTCNGCNGGNATHAAYCAYACNTGYGAYTTYATHGAYTGYGAYCAYGARAAY TGGGAYGAYGTNATHTCNGCNTCNAARGCNGCNCARGCNGGNGCNTGGATHAGYACNTTY YTNTGGYTNTTYATHGGNATHTGYGGNTTYATHACNYTNTGGMGNGCNGGNAARATHCCN TTYYTNCCNGGNGGNGGNGCNGCNAARTCNGAYCCNAAYACNACNGGNCCNGAYACNAAY CARCCNCCNATHGARACNCCNCCNTAYAAYCCNGAYGARCCNCCNAARTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARMGNATHCARMGNMGNYTNTAYCAYGCNTGYGCNAGYGAYTGYGAYAGYGAY AGYGAYATGGAYGGNYTNAGYACNTCNTCNYTNCCNYTNACNGARACNTGYATGGARTAY TTYCARGAYAGYTTYCCNGGNTCNGARGGNYTNGGNMGNYTNGAYATGCCNATGGCNGCN ACNGTNACNAARMGNAAYCARGTNTCNCCNTGYTCNGTNGTNYTNTCNATGATGTAYGCN AARMGNYTNMGNCARMGNAAYAARYTNTAYYTNCARTCNATGTCNTCNACNGAYGTNTTY TTYATHTCNATGATGATGGCNAGYAARTAYYTNTAYGAYGARGGNGTNGARGARGARGTN TAYAAYGAYGARTGGGCNGCNAGYGTNGGNCAYGARACNGAYGAYGTNAAYCARATGGAR ATGGAYTTYYTNAARGARATGGAYTGGCAYYTNTTYGCNAARCAYGARGAYTTYGAYAAY GCNYTNACNGCNGTNGARMGNMGNYTNGCNYTNAARGARGGNGTNAARMGNGGNTGGTTY ACNTAYACNGARATGGCNGTNYTNYTNGAYTGGGAYCCNYTNTGYAAYYTNTGGAAYCAR GTNGGNATGGAYTGYACNAARATGGTNTCNYTNYTNTCNGCNGTNTAYGTNGCNAGYYTN GTNAGYATGATGGGNTCNGCNGCNYTNGCNYTNCARYTNTCNGGNCCNGTNGCNTCNGCN ACNGTNGCNGCNATH--------------------------------------------- ---MGNTGYTGYCCNMGNTCNTGGAAYTAYCARTGYMGNAGYAGYAAYGTNMGNYTNCCN TGYTTYTCNCAYTAYTAYGGNAGYGTNMGNGARTGGTGYTGYCCNATHTGGCCNTCN--- ---GTNTTYGTNAARMGNTGYATGTGYAGYCARTGYGCNGTNYTNACNCCNACNTGYGCN CAYGARGGNMGNTGYCARMGNMGNTAYTCNMGNMGNAGYTTYYTNGCNGTNTGYTAYMGN AAYAAY---CARTGGGGNAAYYTNMGNTAYATHACNAARTAYYTNCCNTCNAGYTGYTAY TGYMGNYTNAARACNAGYGCNTTYTAYGTNYTNGTNATHATGGGNGGNTAYGCNGAYATH GTNTGYACNATHYTNAAYACNTAYTAYAARGCNTTYGGNYTNAAYTTYTAYCCNGAYGAY AAYTTYTTYAAYTCNATGGGNGTNTGGATGAARGTNAGYGCNATHYTNGCNAAYTTYYTN TCNGGNATHGCNAGYGAYAARTTYGGNGTNAARACNGCNGTNGTNGCNTCNACNGCNATG TCNTGYYTNYTNTCNGCNTTYTTYTAYYTNTCNMGNCAYCARTGGYTNTAYTTYGTNGGN GTNYTNTAYAAYGGNTCNGCNATHTGYGCNTTYAAYYTNATGACNGTNTGYGCNTCNGTN TAYTTYGAYAARGARYTNACNACNACNGTNCARGGNATGGCNYTNGTNTCNYTNYTNGTN ACNAAYACNGCNATGCCNATHGGNGCNAGYTAYATHYTNTCNTCNTTYGGNTGGYTNCAR YTNTTYACNTCNGTNACNGTNTTYATHYTNTTYGCNYTNYTNATHTTYATGGTNTGYGTN CCNTGYTTYYTNATHCCNATHATHYTNTGGATHTTYCAYAARTTYATHCARCCNTGGYTN TCNMGNATHTGGAGYGGNTCNGARAAYTAYGTNACNAGYAAYYTNACNTGYCCNATGCCN CARAARAARAAR------------------------------------------------ ---------------------------------------GGNACNACNGCNCARCARGAY ACNMGNTTYTCNGAYAARAARAARAARYTNATGAARACNATGAARTTYGGNGARAGYYTN GARAARAARGTNGAYATGACNAARGTNAAYGTNGAYAGYYTNAARCCNTGGATHGCNCAR MGNGTNACNGAYYTNYTNGGNATHGARGAYGAYGTNGTNGTNGARTTYGTNTAYAAYCAR YTNGARGARMGNCAYCCNGAYGGNAARGARATGCARATHAAYYTNACNGGNTTYYTNAAY GGNAARAAYGCNMGNGTNTTYGTNTCNGARYTNTGGACNCAYYTNTGYAGYGCNCARGAR AAYGTNACNGGNATHCCNAAYGARTTYYTNGARCARAARAARAAYGARATHAARCARMGN CARGARGARCARGARMGNYTNCARGARCARYTNAARYTNAARGARGARCARATHAARGAR CARYTNTCNMGNGARMGNAARGARYTNGARAARAARGAYYTNAAYAAYYTNTCNCCNGAY MGNCCNAARCCNATH---------------------GARACNAAYGGNATHAARCCNYTN ATGGAYGTNGARGAYAGYGCN------------GAYYTNAARGCNGARATGAARTCNGAR CCNAARATHGAYGGNGARCCNCAYGGNGARGGNGARGTNAARAARGAYCARAAR------ ------------------GARAARGARAARGARMGNGAYMGNACNCCNGAYAARMGNGAY MGNGAYMGNGAYMGNGAYMGNMGNMGNCAYTCNMGNTCNCCNGAYMGNCAYMGN---CCN MGNTCNMGNACNCCNGAYMGN---CAYMGNMGNGARMGNGAYMGNMGNCARGAYTAYGGN CAYMGNMGNTAYTCNCCN------------------------------------------ ---CCNMGNMGNMGNTCNMGNTCNCCNMGNMGNMGNTCNCCNCCNCCNAARMGNMGNTCN CCNCCNMGNMGNTCNCCNTCNCCN---------CAYAARAARMGNTCNCCNCCNAARGCN GARGCNGCNAARMGNGAY---------MGNTCNAGYAGYGGNAGYAGYTCNAGYGGNTCN GARGAYGAR---------TCNGGNAARGAY------TCNTCNCCNGARAARAGYGGNATH CARCARMGNMGNAAYTAYMGNAARCAYGAYGAYGAYAGYGGNAARGARTCNTCNTCNTCN GAYGGNGGNGCNGCNAARGAYAARMGNMGNCCNTCNCCNCCN---------------MGN GAYMGN------------MGNAAYGCNMGNAGYCCNTCNCCNMGNMGNMGNMGNTCNCCN CCNTAYMGNMGNCCNAGYCCNMGNMGNCARAGYCCNCCNMGNMGNMGNTTYCCNTCNCCN CCNMGNMGNMGNATGAGYCCNGTNCCNCAYMGNMGNAGYCCNTCNCCNMGNMGNMGNTCN CCNGGNMGNYTNTCN---CCNMGNMGNMGNAGYCCNCCNMGNTAYMGNMGNCARGCNTCN ATGTCNCCNMGNMGNMGNMGNATGTCNGCNTCNCCNCCNMGNMGN---CCNCCNTCNCCN TTYCARGGNMGNMGNMGNMGNCCNTCNMGNTCNCCNTCNGAYTCNCCNGTNAARMGNMGN MGNCCNTCNCCNCCNCCNTCNCCNCCNGCNAARTCNAARAARAARMGNGTNTCNCCNCCN CCNTCNGARTCNGARGAY------TCNTCNAGYTCNGAYGAYTCNTCNCCNTCNCCNCCN CCNGCNTCNAARMGNCCNTCNAARGGNAARGARCARAAR---------CCNTCNAARMGN CCNCCNCCN---------CCNACNAARCARGCNAARTCNTCNAGYGAYGAYAGYTCNTCN TCNGGNTCNGARGAYAGYGAYGARGAYTCNGAYTCNGAYGARGCNACNCCNCCNMGNYTN GTNAARTCNTCNCARAARCARAARCARACNCCN---------------CCNTCNAAY--- ------------AARMGNAARCCNTCNCAY---------------GGNTCNMGNTCNMGN ---------------------TCNMGNTCNCCNGTNAAYMGNMGNGARMGNMGNCCNAGY CCNCCNCCNCCNMGNAARMGNACNGGNTCNMGNTCNCAYTCNMGNTCNCCNGTN------ ------------CAYMGNMGNGAYMGNCCNGCNTCNCCNCCNCAYMGNMGNGGNTCNCCN CCNMGNGARGARTCN---------------TCNAGYTCNMGNMGNCARMGNMGNGAYACN GAYCCNTCNGAYCCNGAR---YTNGGNMGNMGNGAYMGNMGNCCNAGYCCNCCNMGNAAR MGNCARGTNMGNTCNCCNTCNCCNAAYMGNGARMGNGAYGGNGGNAGYGGNMGNMGNTCN CCNCCNCARCCNGARMGNCCNAARMGNCCNCCN---------------TCNTCNGAYAGY AGYAGYGAYAGYAGYTCNGARGARGAYGARAARGAYYTNAARAAYAARTCNAARGCNGCN CCNATGAARCCNTCNAGYGGNMGNCCNGCNMGNMGNTCNTCNCCNGGNGTNGCNGCNAAR MGN--------------------------------------------------------- ---------AARCAYTCNGCNAGYCCNTCNCCNCCNMGNGCNAARGTNTCNMGNMGNGAY GCNAARGAY------GAYGAYAARCARMGNAGYGAYAARCCN------------------ ------MGNCAYMGNTCNGTNAGYCCNAAYMGNCAYGTNACNTCNCCN------------ ---------------------------------------CCNAAYGGNAARGGNTCNCCN CCNCCNTCNACNAARCCNAARAARGAYAARCCNGTNGARTCNGCNAGYAAYAGYGAYTCN GARGGNTCNGAYTCNGAYAAYGCNTCNAARAARAARAARAARAARAARGAYAARAARCAY AARAARCAYAARAARCAYAARAARCAYAARCAYAARAARGARGTNCCN---------GAR AARGGNGARGAYYTNGARCARMGNYTNMGNGARAARGCNYTNATGTCNYTNYTNCAYMGN AARAARAARCARGCNTCNCARGAYCCNGAYAAYGAYTCNGAYAGYGGNAGYAGYAGYGGN GARGARACN--------------------------------------------------- ---------------------------------------YTNGAYYTNGARGGNGCNGCN TAYCCNYTNTTYGCNAAYMGNMGNACNMGNAARGARACNTTYGTNTCNTGGGAYCCNAAY CAYAGYCARAARCCNGARGARYTNGTNAAYYTNGGNTTYTTYTAYGCNGGNTAYTCNGAY TGYGCNMGNTGYTTYTAYTGYGGNYTNGGNYTNAARTAYTGGMGNCCNAAYGAYGAYGCN GCNTAYCARCAYGCNMGNTTYMGNCCNCARTGYAARTAYAAYCARTTYGTNAARGGNCAR GAYTTYATHGAYCAYGTNCARMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYGAYYTNAAYATHYTNYTNGTNGGNGCNGGNGAYATHMGNCAYATHYTNACN ACNATHGCNMGNMGNTGYMGNTAYAARAARMGNAARYTNAAYTTYTTYGTNGTNGAYTCN GCNYTNGARYTNTAYGCNMGNGAYATGYTNYTNATGATGGTNGTNYTNGARATGCARCAR AAYATGGGNYTNCARGARAARACNGARGTNTTYYTNGARATHCAYGGNAAYACNYTNYTN MGNCARCARACNAGYGAYTAYATHCARAARATGTCNCAYCARYTNATHMGNATGGTNACN GAYTTYGAYTAYATGGARAARAARTTYCCNATHTTYGAYYTNAAYCARYTNAARTAYAAR GARMGNGAYTTYYTNGARGGNGTNYTNAARTTYTGGMGNAAYCARGARAARGTNAARAGY CCNTTYGAYATHAGYAARTGYTGGGAYYTNMGNYTNMGNCARYTNYTNGGNGTNMGNTAY GAYAGYMGNYTNAAYGCNTTYGAYTGGGAYTAYAAYATGGARYTNATHGARMGNGGNGGN TCNATHATHCAYYTNCARCARTAYAARTCNTGGMGNGGNGAYGGNATHGCNTAYACNATH MGNGARGGNACNTAYGAYGTNCCNAAYMGNACNATGTCNTCNGCNATGGTNTTYAARCAY GARGGNGARMGNTAYCCNMGNMGNGGNTAYTGGGGNGAYATGGTNGTNTCNCCNTAYGTN GCNTTYGGNGTNGARACNGARGARAARTCNYTNTAYAARAARCARAAYAAYCARCAYACN AARACNGCNGARGAYGTNGCNGARTAYAAYATHACNTCNYTNYTNCAYGARYTNATGACN GGNGARAARTAYGTNYTNCCNAARGTNGARGTNAARGAYGGNAARGARGARGARAAR--- ------CARACNGCNACNYTNGARGARATHGTNGARGARACNAARGAYAARGARAAYCAR GARGAYACNAARGCNAAYGGNGGNGAYGCNAGYGARGARAARGARGARTCNGARTCNAAR ATHCCNGAYAGYGARYTNTAYGARTGGMGNTCNYTNGARGAYGTNAARGTNACNTTYYTN CCNYTNTCNTGYGTNAARGARYTNGCNAARAARAGYAARTAYCARAARTTYTTYAAYATH GTNTCNTTYTCNAAYAGYATGGTNCAYYTNYTNACNCCNGARGTNGCNTCNATHTTYTCN GAYAARTGYGCNATHGTNYTNGARACNGCNYTNTTYATGYTNAGYYTNAARAARCCNGAR GTNCARGARTTYGTNAARMGNGTNAAYGGNYTNGCNAAYGCNGCNGGNTGYAARCCNYTN GAYGCNGTNGAYGAYYTNCARGAYTCNTAYACNTCNTTYTAYTTYGARMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNYTNYTNYTNTCNTTYTTYATHYTNTCNATHTCNATHACNATHGCNATHAGY MGNCCNMGNGGNGTNTCNYTNGARAARGCNTCNTTYTAYCARYTNGAYACNGARTTYCAY TGYYTNACNAGYGGNAARGTNYTNCCNGCNGAYCAYGTNAAYGAYGAYTAYTGYGAYTGY GARGAYGGNTCNGAYGARCCNGGNACNTCNGCNTGYTCNAAYGGNYTNTTYTAYTGYGAR AAYMGNCCNTAYAARGGNCAYTAYATHAARTCNTCNMGNGTNAAYGAYGGNATHTGYGAY TGYTGYGAYGGNTCNGAYGARTTYGAYGGNATHATHGCNTGYTCNAAYACNTGYGTNGAR AARTAYGARCARGARMGNGCNMGNCARGARGTNYTNMGNCARCARCARTTYGARGGNTAY AARGTNAARCARGARTAYATGCARCARGGNAARMGNGCNAARGAYGARAARMGNTCNAAR YTNAGYGARYTNGARMGNGARAARGARGTNYTNACNMGNGARAARGARATHGCNGARACN GCNAARAAYGARGCNGARGARCCNGARAARGCNGCNATHGARGARCAYAARAARGCNTGG GARYTNGTNAARGARGARMGNCARAARGCNAARGAYGCNGTNAARGCNGCNCAYGCNTTY TCNACNYTNGAYGTNAAYAAYGAYGARAAYGTNGAYTAYCCNGARYTNATGAARCAYAAR GARTTYGAYATHGAYTCNGAYGGNACNGTNAAYGARGARGARGCNAARGARTAYYTNGAR GAYAAYGARCARGTNGAYYTNACNGTNTTYACNGARAARATHTGGCCNAAYATHAARGAR ATHTAYAARATHGCNAARCCNGARGGNCAYGTNCCNAARGARCCNACNGAYCARGARCAR AARGAYGAYAARGARAARGAYCCNGAYGTNGTNGARGGNGGNTCNCCNGAYGARGARATH GARGARGAYGAYGAY--------------------------------------------- ---------------GARGARAARGARCCNGARTAYAAYGARGARACNAARMGNYTNATH GAYGTNGCNGAYCARACNMGNACNAARTTYAAYGARGCNGARMGNAARGTNAARGAYGCN GARMGNGARATHGAYGAYATHAARAARTAYYTNGARATHGAYTTYGGNCCNAAYGARGAR TTYGCNTTYYTNAARGGNCARTGYTTYGARTAYACNGAYMGNGARTAYACNTAYMGNCAY TGYCCNTTYGAYAARAGYACNCARAARAAYAARAAYGGNGGNATHGARACNTCNYTNGGN ACNTGGGGNAARTGGCAYGGNCCNGAYGAYGAYAARTAYGAYACNATGAARTAYGARAAY GGNCARGGNTGYTGGAAYGGNCCNTCNMGNTCNACNCAYGTNAAYYTNCAYTGYGGNTCN ACNAAYACNYTNACNAGYGCNTCNGARCCNAGYMGNTGYGARTAYCARTTYGARTTYACN ACNCCNGCNMGNTGYGCNGARCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNCARTGYTAYYTNYTNCCNACNGAYGCNCCNYTNGGNTAYAAYCAY AGYCAYTGYGTNTCNGCNGAYGCNATHYTNTTYAAYGTNYTNYTNCARMGNAAYCCNAAR ATHTGYTGYATGATHYTNGAYATHTGYMGNYTNAARMGN---GARGGNTGYCCNGAR--- ------YTNYTNAARCCNCCNGAYGGNGARTAYGTNGTNTGYTAYGGNACNTCNCAYGGN AAYTTYGCNTAYGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TTYATHYTNATGGCNYTNCCNTAYCAYATHTAYGCNACNTAYACNACNATH AARGARAAYAARGAYAAYTTYTCNAGYTAYATGAAYCCNATHGCNTAYTGYTTYYTNTAY YTNAAYTCNATGTGYAAYCCNATHATHTAYGCNTTYMGNTCNCCNGCNTTYMGNGARGGN TAYAARGARATHYTNTGYCARACNCCNAAYTAYGTNATHMGNGAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNGAYGTNGGNTTYGAYGARMGNGARATH YTNCCNGAYGAYGARCAYYTNGAYGAYGGNYTNTAYAARACNGCNGCNGTNGAYGARMGN GARGARGTNGCNGGNAGYAAYCAYMGNGGNGAYGGNYTNGAYGAYAARGAYAARCCNATG GAYATHGAYYTNCCNCCNCCNGTNGTNGGNGAYGGNTTYGGNGAYGGNTTYATGGAYGAY GAYGAYGGNTGYGARGAYGAYAAYGAYAAYTTYGGNGAYGTNGAYCARGAYTTYTTYGGN CARGAYTTYATGGGNACNGGNGGNYTNTTYGARGAYCCNCCNGTNATGCCNAGYGARTCN TCNGCNCCNGARTCNGTNCARCCNCCNTCNTCNCCNAARGARGAYGTNGARTCNAGYAAR CCNAGYAAYGARGCNGARGAYACNGTNAAYYTNCARGCNAGYAAYGCNGGNGTNTCNGCN GTNTCNAGYGTNACNGGNGARCARACNACNYTNGTNCAYAAYGARGARGARGCNTTYGCN YTNGARCCNYTNGAYATHACNTCNGTNCCNGGNACNGARMGNAARGGNAARMGNAARMGN AARYTNATHGTNGAYGARCARAARGGNATHCCNAGYGARACNATGAARYTNCARYTNTCN GAYACNTCNGAYATHGTNACNTCNYTNGAYYTNGCNCCNCCNACNAARAARYTNATGYTN TGGAARGARACNGGNGGNGTNGARAARATHTTYGTNYTNCCNGGNMGNCCNATHATHTCN AARATHAGYAARCAYYTNTTYTCNATHAAYYTNGTNTGYAARTCNGTNGCNGAYGAYTAY GAYCCNGGNGCNAGYMGNATHGAYYTNGAYATGGCNCCNGARGTNGCNMGNGARAAYGAR MGNAAYAGYACNYTNCARGAYACNMGNYTNTCNGARATGTCNACNATHGTNGARGARCCN TCNGARGTNTCNMGNMGNTCNTCNMGNAAYCARGARATGGTNGAYACNTCNMGNMGNTCN GARCCNTCNGTNGTNGAYAAYCARTCNYTNTTYGAYCARATHCCNGAYACNATHCARCCN GCNGAYATHCCNACNGAYCCNAAYAGYATHGTNCCNACNATHAAYTCNATGYTNGAYGAY GGNCCNCCNTCNGTNGCNCCNTTYTCNGTNCCNCCNCCNCCNTGYGTNACNTTYGAYATG GAYCARGARCARGAYAAYGAYYTNATGCCNGARAAYGCNGARCARGARGARAARMGNTGG AGYAARMGNACNCARGTNATGCARGAYATHTTYGAYMGNGGNTTYAAYGAYCARGAYTGY YTNAGYTTYAARGAYATGGCNGTNAAYYTNAAYMGNAARCARGCNGCNTCNMGNTTYTAY ACNYTNYTNGTNYTNAARAARCAYCARGCNATHTGYACNGARCARCCNGARCCNTTYGGN GAYATHTAYATHACNMGNGGNCCNCARTTYGGNATHGCNTGYTTYAARCARGARGAYGAR ACNTTYATHAARATGTTYAARYTNACNGAYATHATHTTYATHAGYACNGGNYTNTAYGAR CARACNYTNAAYATHGARAGYMGNGAYAARAGYMGNCARAARCARMGNYTNTGG------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARACNGGN ATHATGAARAARGCNTAYGARYTNTCNACNYTNACNGGNACNCARGTNATGYTNYTNGTN GCNAGYGARACNGGNCAYGTNTAYACNTTYGCNACNMGNAARYTNCARCCNATGATHACN AGYGARAGYGGNAARTCNYTNATHCARACNTGYYTNAAYTCNCCNGAYCCNCCNCCNAGY TCNGCNGTNACN---AAYTCNYTNGARCARMGNATGAAYCCNTCNGGNTTYGARGARACN GARYTNTCNTGYGTNCCNGARGARGARCARAARGTNTTYGAYAGYAAY---AAYGGNAAR CCNGTNTTYCCNATGGGNACNCAYGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNTAYGARGARGARTCNGTNTTYTTYCAYACNTCN CCNGAYATHGGNMGNCARATHTCNGAYYTNMGNGCNCAYATHMGNGAYTTYATHYTNGGN CAYGARGARAARATHGARGCNYTNGARAARYTNGTNYTNMGNAARAARCCNTCNCCNATG GARATHGARYTNGCNAARTTYCAYGTNGARAARGARYTNTTYGCNYTNTCNCARCARTTY GCNYTNTAYGARAAYGGNCARTTYGAYATHCCNTCNATHAAYAGYGARGAYAARGARGGN AGYCAYCARCCNGARAGYGTNYTNACNAAYGAYGCNTTYAGYAGYAARTCNCAYCARAAR TAYGTNCCNCARACNGCNCARTAYGTNAARGCNTGYAARGARACNGARGTNTCNGAYTCN GTNMGNAARGARATHTCNYTNYTNCARAAYGARGTNGARAARYTNGARCARGARYTNAAR CARATHCARATHAAYAAYYTNAARMGNYTNCARAGYATHACNGARCARGAYAGYAGYTCN ATHTGYATHYTNCCNMGNCAYTTYAARCARTTYYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GAYGAYATHTAYCAYTCNCCNYTNGAYTTYGCNAARGAYATHGGNAAYGCNATHACN GGNYTNGTNGAYTAYYTNGAYGCNGAYYTNYTNGARAAYGARGARGCNTTYAARGCNGAY YTNTAYCCNYTNGAYCCNGARGAYATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGNTGGATHGCNCCNGAYGGNATHMGNAAYAARYTNGAY TGGYTNTCNTCNTGGGARGTNYTNACNCAYAARCCNGAYGGNGAYMGNGTNAGYCCNATH AAYGCNCAYYTNGAYTAYGARAGYATHYTNTGYATGCCNCARAARGAYAARGAYGGNAAR YTNCCNCCNYTNATHGTNTTYGTNCAYGGNGGNCCNCAYGTNGGNTTYGAYTCNTCNTAY AAYCCNATGACNAAYTTYTTYTGYYTNTGYGGNTAYGCNGTNYTNATGGTNAAYTAYMGN GGNTCNTGGGGNTTYGGNCARGAYTGYATHGARTCNYTNYTNGGNCAYGTNGGNGAYATG GAYGTNAARGAYGTNGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGTTYCCNATHTTYCCNATH YTNGAYGCNGCNGCNTAYGAYATHYTNGGNGARGARMGNCAYATGTGGGGNAARCARMGN YTNTGGGGNACNTTYGGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AAYACNCCNYTNCCNMGNCAYAARMGNCCNTCNCAYMGN MGNGCNGARGTNAARMGNMGNGAYAARATHAARACNACNYTNGAYGARATHAARTCNAAY ATHCCNTCNYTNCARGAYAARGGNAARCCNAGYGARTCNGCNATHYTNTTYAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYTAYYTNCARTAYTAYCARTGGTAYGGN CAYYTNTCNGARGGNGTNCCNTCNTGGCCNATHTCNGGNATHTAYYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CCNGGNATG YTNGCNTTYYTNAAYMGNCARGAYACNTGYTAYACNCCNGARAARTTYTTYGAYMGNACN ATHAAYYTNGAYTAYTTYGGNTGYCCNGGNCCNGTNTAYATHAAYGTNATGMGNGCNYTN TGGGAYTTYGCNAARATHGTNYTNTTYYTNTTYTTYGTNYTNATHATHGTNYTNGCNTTY GGNGAYGCNTAYCARATHTCNTCNACNAAYCARYTNYTNGCNACNGTNGTNGGNGGNTTY ATHCCNTTYATHTTYAGYCAYTTYTTYTCNNNNAAYACNGAYGTNTCNGGNTTYAAYAAR GAYAGYGTNCARTTYGCNACNGARTTYCAYACNGCNATHAAYMGNTTYGARCARGCNTGG CCNGTNTTYGAYATHATHCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYAGYGGN---MGNYTNTCNGCNYTNCCNCAYYTNAAYCARTCN YTNTCNGAYYTNCAYTTYMGNCARAGYYTNATGCARMGNATHCARGARTGGTCNAGYTTY GCNGARGARTAYAAYAARTCNATGTCNCCNACNCCNGARTGYTCNCCNATHMGNTTYGTN MGNMGNAGYMGNTCNYTNGAYMGNCAYYTNAGYGAYTCNTCNGTNATHGCNACNGARTCN GARATHCCNTCNTCNAARCCNYTNGARATHGARCCNATGACNGARAARAAYYTNGARACN YTNGARTAYGARYTNCAYGAYATHCARGGNGARTTYGARTCNATHACNTCNAARYTNCAY GAYYTNATHGARCARCARGCNACNCCNACNGTNACNCCNTCNCCNTCNCAYGCNCCNATG TCNTCNTCNTAYCCNACNGCNTTYATHTCNMGNAARTCNTCNACNCCNTCNTTYACNTCN ACNTCNAAYCAYTCNCAYTCNTCNCCNTCNCCNAARMGNAGYAARAGYACNCCNTGYGTN AAYAGYTCNACNAAYYTNMGNAARATGAARACNAARTGGGARMGNGTNCCNGGNTCNGCN TGYTCNGAYTGYAGYMGNAGYTCNMGNGGNAGYAGYGTNGARTAYGTNTGGGAYATGGCN GAYTAYACNGCNAAYTCNACNAGYCCNGCNACNGGNMGNMGNGTNTCNYTNGGNGGNATH ACNTCNACNGAYYTNTGYGAYGTNTGYAAYATHAAYCCNCCNGTNTCNGTNATHGARTAY TGYCARCARGARTGGAARGGNGAYACNCCNMGNGCNACNGTNATHMGNCARGGNTAYCAY CARATHCCNTCNYTNATHCARTGYGARMGNATGTGYGTNATHMGNGGNGAYAAYTAYTGY GCNYTNMGNAGYACNYTNTTYCARGTNYTNGTNGARGGNATHMGNATHGTNCCNAGYTCN TGGGGNATHATHGGNATHATGGAYMGNYTNCAYGAYCAYTTYGAYGAYCCNACNATHCAR ATGTCNGCNTGGAAYTTYGCNAAYMGNYTNCCNGGNCAYTGYAARGAYAARYTNGCNTCN ATHTCNAARTGYGCNYTNTCNYTNTAYGCNACNGTNGARGARGTNTGYAAYYTNCCNACN MGNGARGARMGNGARAARMGNACNATHAAYYTNTTYAAYGCNAGYTCNACNTTYGAYYTN GARYTNYTNGARGGNGTNAARGTNATGATGYTNYTNCARYTNGTNTCNYTNMGNCARMGN ATHYTNGAYGGNGARGARGTNCCNATHTTYGGNCAYYTNYTNTTYGCNMGNGAYACNTCN GTNTCNGTNGCNGAYTTYATHAARAAYCAYYTNAAYAGYGTNGGNGAYTCNGGNGGNYTN GARCARGTNGARATGTGYYTNYTNGGNTAYACNYTNGGNGTNAGYATHMGNGTNYTNMGN YTNTCNCARGCNGGNCARGARGAYTTYGARTGYTCNTTYCCNGAYGAYATGCCNTCNGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TAYYTNATHTCNCCNGARTAYCAYYTNATHTCNACNGTNGAYGAYATGGGN ACNGCNMGNATHTTYYTNTTYGCNTTYGAYCAYATHTTYTTYGTNAARGCNYTNAAYGAR AAYAGYCCNGARGGNACNTCNAARATHYTNTGYCARAARTGYGARGCNTCNAGYGARGGN GAYTAYYTNGGNGTNTCNTTYGARAAYACNGGNAAYAARGARATHTGGYTNGARGTNCAY AARYTNCCNGTNGARAAYTGGYTNAARGARYTNGARGTNATHCARAAYGCNATHGGNAAR ATGAARGAYGARCARGARAARTCNCARATGGARACNGCNGGNAAYGCNGGNGAR---GCN GAYCAYGARGCNGTNCCNAARTCNGTNGAYGAYACNAARACNGAYGARCCNGTNGTNAAY GTNGARTCNGTNATHGARAARYTNGGNTCNAARTTYAGYGGNCCNTCNATHGTNTTYAAR GCNAARCCNCCNGCNCAYCARTTYCCNGCNCCNAAYCCNTCNAGYAAYATHGCNTCNGCN GTNTCNAARGTNGAYCAYGGNGAYGTNATHGGNACNGGNACNAAYCAYGTNYTNAGYTCN GCNCAYYTNGARTCNMGNGAYGCNATGTTYAARCAYMGNCAYCARGGNYTNYTNGARTTY YTNCCNACNGARGARGARGARAAYCARATHTTYGTNACNTTYCAYTTYACNAAYCCNAGY MGNATGATHCCNYTNGGNATGGAYCCNTCNTCNCCNCAYGAYAARCCNGTNTCNYTNTTY YTNTGGTGGTCNGGNACNCAYCAYYTNTGYCAYTAYTCNYTNYTNAAR---ACNGGNAAR GAYATHGARTTYAARCCNGAYATHGTNTGGCCNTGYTCNAAYACNATHACNTGYTCNACN GTNAGYCCNTGYGGNTCNCAYYTNGCNGTNGGNATGGCNAAYGGNAAYYTNGCNYTNTGG GAYTAYCARATGGGNYTNCCNAARGCNGTNYTNACNGTNTGYGGNAAYGGNGGNGTNAAR GAYYTNMGNTTYYTNGAYCCNACNYTNTTYCCNTCNGAYCCNCCNGARTAYCCNCCNTAY CCNGTNTCNTCNGCNACNTTYATHYTNGCNGARTAYTCNGAYGGNACNCARGCNYTNTTY GAYACNTGYGAYGGNAGYCARCARATHCCNMGNGTNGTNGCNTCNGTNCCNGARAAYGAY GAYGAYATHCARACNYTNATHAARATHATHCCNAAYYTNCCNGARYTNATGYTNTTYGTN AARAARAAYGGNTGYATGTAYATHAARGAYATHGGNACNGGNGCNTCNYTNTGYCARGTN GTNYTNCCNTCNACNCAYGCNATHCARACNCCNTGGAAYCCNATHTTYGCNYTNGGNGCN GGNAGYCARGTNYTNTAYYTNAARGGNGARGGNCARGAYGTNAGYGARGARGGNGARGTN AAYGAYGTNTCNTGYYTNTTYAARTTYAAYYTNMGNGAYTAYCCNATHYTNGCNGARTAY TGGGCNMGNCCNMGNGARAARACNGAYYTNATHGTNTAYACNACNTAYCARCARMGNYTN GAYTCNYTNATGAARGARMGNYTNCARCARCARGCNATGMGNAARCCNMGNATGCARAAR CAYTGGGGNCARYTNMGNGGNGARYTNGAYATHATHCARAAYGCNMGNGARATHCCNGTN GAYTCNYTNMGNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNACNGCNTAYGCNACNCCNCCNACNYTNYTN CAYMGNGTNGGNYTNGARTCNAGYTCNACNGGNTCNTCNTTYCCNGCNGAYTTYACNAAR CCNGTNCCNYTNGCNGTNATHTCNCCNGGNMGNMGN---CCNAAYACNAAYATGGAYAGY CCNTGGGGNAARTCNAAYCARGTNAAR------CCNTGYTCNYTNGCNGAYGTNATGAAY GARCARYTNGCNTCNGARYTNCARAAYAAYCAYATHYTNAAYCARGARYTNCARGTNATG GARAAYYTNGARACNACNACNGAYGAYTCNGARGTNGTNTCNCARTCNACNGAYACNGAR YTNACNGAYGCNGARYTNGCNGCNAARYTNGCNGCNGARGARGGNAAYTGYGAYCCNAAY GAYGARATHATHGCNYTNATGYTNCARAARCARTAYGAYMGNGARTAYGAYGCNGCNYTN TCNCAYMGNGARCARAARTAYAAYGGNAAYTGYAARGTNGGNATHTCNTTYGAYAAYTAY AARMGNAARCAYATGCARACNGARTAYCARAAYGARGAYGCNGARGAYGAYGAYGAYTTY TAYGARGARGARMGNCCNGARCAYCCNCARMGNACNCARTGGGARAAYGGNACNACNACN ATHGGNAGYMGNGGNTAYGCNAARCARGGNGAYAAYATHGTNACNAARCAYGAYAARGTN ATHTGYGGNMGNMGNAAYGCNCARMGNYTNATGCARTTYCCNCCNGAYTTYGAYAGYGGN GAYGGNGARGGNATGGAYATGCARYTNCCNAAYMGNGTNTAYAAYAARYTNAARCARCAY TCNCARGCNGARATGAARAARGGNCAYAARGTNYTNGARAARAARGAYCAYTCNACNGCN ATHAARGCNGTNGAYGARAARACNMGNATHYTNATHTTYAARATGATHAAYTCNGARTTY YTNAGYTCNGTNGAYGGNGTNGTNAGYGARGGNAARGARGCNGTNATHYTNAARGCNATH GGNGGNMGNAARGAYCAYGTNGARYTNCCNMGNGAYGTNATHYTNAARGTNTAYAARACN TCNATGAAYGARTTYAARACNMGNYTNAARTAYATHCARGGNGAYTAYMGNYTNTCNAAR GAYATHYTNAARAARTTYAAYCCNMGNAARYTNATGMGNATHTGGGCNGARAARGARTTY YTNAAYYTNMGNAARYTNMGNMGNCAYGGNGTNCCNTGYCCNGAYCCNYTNGCNCARAAR AARCARGTNYTNGCNATGACNTGYATHGGNGGNGARMGNCCNGCNCCNAARYTNAARGAY GTNGTNTTYAGYACNGARGAYTTYCARGAYGCNTTYGARCARACNGTNGARYTNATGAAR YTNYTNTTYGAYAARTGYAAYATGGTNCAYTGYGAYTTYAGYCCNTAYAAYYTNYTNTGG CAYCARAARAARGTNTGGGTNATHGAYGTNGGNCARGCNGTNGAYMGNGAYAAYCCNAAY TCNAAYTCNTTYYTNTTYMGNGAYTGYMGNAAYATHTGYGAYTTYTTYAARYTNGGNGGN GTNCAYGGNGTNCCNTCNGCNGARGGNYTNTTYAAYGARATHACNAARTAYGCNTTYGAR GGNGARGGNGARGTNTTYGARTCNCARGTNCAYMGNTAYGAYGARGARGGNTAYGCNTTY GAYTTYTTYTTYGARYTNTCNAARTCNGCNCARTCNCARGARYTNTGYGGNAAYAGYAGY GGNAGYGARAGYGARGARGGNGARGARGARGAYGGNAGYGAYGGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CAYAARTAYCCNGTNATHTCNYTNGGNTGYATHYTNAAYGTNGGNAARYTNATH TCNGTNGAYAGYAARGGNTTYATHAAYGTNTGGAARTAYGAYAARCARCAYGTNACNCAR TTYGGNTGGTAYTTYCCNGAYAGYAARTAYMGNATHGAYTTYAAYAARATHATGTAYTCN CCNGCNCCNGGNGGNAARGTNAARGTNATHTTYACNGAYMGNAAYMGNTCNAARACNACN TCNCARGCNGCNATHGCNMGNGARMGNMGNGARGCNCARGCNTCNYTNGAYAAYATHCAR YTNGGNAAYCCNTGGCAYGTNAAYGARGAYMGNCCNGGNYTNGARACNTCNATHTAYATH CCNTCNGGNGGNTCNATGGARTCNGGNGCNATGTTYAAYATHATHATHMGNCAYACNMGN ACNCARCARYTNTCNACNTAYATGACNAGYTAYTAYACNCCNGTNAARGTNGGNTGYTCN AARYTNYTNTCNGCNMGNYTNTCNCCNTCNGGNAARCARATGGTNTTYGTNYTNYTNTTY CCNCCNTTYCCNCCNAARGAYGCNCAYYTNATGGTNYTNGTNYTNGARYTNCCNTCNGTN ACNYTNMGNCAYTTYMGNTAYGAYCAYCCNGTNTCNGAYCARCARCAYMGNGAYYTNGCN ATHGAYAARGTNTGYTCNGCNGARATGAGYCARGTNTAYGGNCCNACNGGNGCNGAYTAY YTNTTYYTNACNGTNGGNGGNGAYTTYACNTGYGTNTCNYTNGCNACNGGNTGYGGNGTN YTNMGNATHGAYAAYACNTCNMGNCCNMGNGTNGGNAAYTTYMGNGGNYTNGTNATHGAY GARAARCARTTYCCNYTNTCNMGNACNCARAARGTNTGYYTNGTNGGNAAYATGGGNTCN YTNTAYGCNGTNTTYTAYGAYCARAGYACNACNGGNYTNAARGTNYTNMGNYTNGARGAY GGNAAYAAYCAYGARGAYGCNGTNMGNGTNTGGAARGCNTTYCARCARTGGGARMGNTTY GARGCNACNCCNATGGARATGMGNGTNAAYCCNGTNGAYTGGGCNYTNCCNGAYATGAAR CAYAARYTNGCNGARATGMGNAGYYTNATHYTNTCNYTN------ACNGARGTNGAYGTN GGNATHACNGARTAYYTNGGNTCNCARACNGARTCNTTYTCNGCNGTNATHAARCARMGN TAYTCNGAYTTYATHGTNAAYGARATHGAYGARAAYGGNGCNATHGTNCAYYTNAARAAY GTNACNCAYGARGARGARAARGARGARGAYGGNGARGAYGAYCARAARTCNACNGAYGAY TCNAGYGTNYTNAGYGARTCNGAYMGNGARGCNATHCARAARATHGTNTCNGAYMGNAAY MGNGAYGCNACNCAYAGYATGYTNGCNCCNGAYGAYAARTCNATGMGNACNAARATHCAY YTNGCNGTNAARCARAGYTTYTCNCARYTNGARACNTCNACNACNGARGAYGARAARGGN CARAARGTNATHAARGTNACNTGGMGNAARGGNAARACNMGNGAYGTNATGMGNGAYGAR TGGCCNCARTCNAARAARTCNTGYMGNTAYGTNMGNTTYGTNYTNTAYAARGARAAYAAR GAYACNATGGAYGCNATHGGNYTNATHGCNAARAAYYTNMGNGTNMGNGARAGYATGTTY CARTAYGCNGGNAGYAARGAYAARMGNGCNAARACNACNCARGARATHACNGCNCAYMGN ATHCAYCCNAARAARYTNGTNAAYYTNAAYAARATGYTNTGGAAYATGGGNYTNGGNGAY TTYMGNTAYGTNGARCARCCNYTNCARYTNGGNCARYTNTCNGGNAAYMGNTTYATHATH GTNYTNMGNAAYATHCARGCNAAYGCNGARGTNGTNGAYACNTCNTTYACNTCNYTNAAR GTNACNGGNTTYATHAAYTAYTTYGGNATGCARMGNTTYGGNACNACNGCNATHCCNACN CAYMGNATHGGNAGYGCNYTNYTNAARGGNGAYTGGGARMGNGCNATHGAYYTNATHYTN GCNCCNMGNAAYGAYGTNCCNGCNAARGAYAARTTYCARAARATGTGGGCNGARTCNMGN GAYCCNGCNGCNACNYTNGAYGTNACNCCNMGNTTYTGYGGNYTNGARMGNAAYATHYTN GARGCNYTNGTNAARMGNGCNAARCCNTTYAAYGCNYTNGARAARYTNCCNMGNAAYACN MGNYTNYTNTAYATHCAYAGYTAYCARTCNYTNGTNTGGAAYAARATGGCNTCNAARMGN YTNTCNCARYTNGGNCAYGGNGTNGTNYTNGGNGAYYTNGTNYTNGAYMGNCARCCNTGG TCNYTNAARGGN------GGNGARTCNCCNTCNCCNGTNGTNGTNACNGARGAYAAYATH GGNAAYTAYAARGTNACNGAYGTNGTNYTNCCNYTNCCNGGNTAYGAYATHATHTAYCCN CAYAAYCARGTNGGNGARTGGTAYAARGARYTNYTNTCNTCNGAYGGNYTNGAYGTNAAY AAYATGAARMGNACNCARAARGAYTAYTCNYTNTCNGGNGCNTAYMGNCAYYTNGTNGTN ATHCCNAARGAYGTNTCNTGGACNCAYCAYCARTAYGAYGAYCAYACNCARCCNYTNACN YTNAGYGAYTTYGAYGTNATHCARGGNGARATGYTN---CARGAYTGYGGNGAYACNGGN ACNCARAARGCNGTNGTNYTNCAYATGTCNYTNCCNTCNTCNTGYTAYGCNACNATGGCN YTNMGNGARGCNATGAARATHGAYACNTCNTCNGTNTAYCARACNTCNYTNAAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNCCNYTNTTYCCNAAR GCNACNTCNATGTAYYTNCAYAGYGGNAAYATGATHAAYTGGAAYMGNYTNAARMGNMGN CCNAAYYTNTCNTCNTCNGAYGARYTNTGYGARGTNATHACNGAYACNYTNAAYTCNTAY GTNGARGCNGCNGAYAARACNGARYTNCARTAYGTNACNGARGTNTAYAARGTNAARTCN GARAAYGTNGARATHATHGARGARTGYGARMGNGGNGAYGTNAARATHACNGTNAARGTN TTYATHTGYGAYCCNCARTCNCCNAGYGTNATHGGNGAYGCNGTNAAYAARGTNYTNAAY GARYTNGGNACNACNTTYATHGARACNYTNYTNYTNGCNGTNAGYCCNAAYGGNACNCAR GAYYTNGAYCCNGARGARGCNATGAGYYTNTCNGTNGTNGARGGNTAYTGGAARGCNATG GARGARYTNGTNTCNAAYGAYAARGTNYTNTCNYTNGGNATHTGYGAYTTYGGNAARGAR GGNYTNGARACNYTNTAYAAYTGGGCNCARGTNAARCCNTCNGTNAAYCARGTNAAYYTN GARTCNTGYTGYGTNYTNCCNAARGAYYTNACNGARTAYGCNAARTCNATHAAYGTNCAR YTNYTNACNCAYAAYGAYMGNCCNGCNTTYATHACNAARGARYTNYTNCARGARAARATG YTNGGNGTNACNACNGARMGNGAYAGYGAYGCNTGGACNCCNGARTGGGTNATHMGNTAY TCNGGNATHYTNAARTGYMGNGGNATHATHAARACNAARGGNTAYATHTTYCAYGCNACN MGNGAYAAYAARAARMGNATHYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AAYGGNAGYTCNGARMGNAARAARAARMGNMGNAGYMGN TGGAAYACNGAYAAYGAYGAYAARACNGTNATHCCNGGNATGCCNACNGTNATHCCNTCN AAYYTNTCNGARACNCARCARMGNCARTAYGTNGTNCARYTNCARATHGARGARATHACN MGNAARYTNMGNACNGGNGARYTNGGNATHCCNTCNAAYCCNGARCARMGNTCNCCNTCN CCNGARCCNATHTAYAAYAAYGARGGNAARMGNYTNAAYACNMGNGARTAYMGNACNMGN AARAARYTNGARGARGARMGNCAYMGNYTNATHCARGARGCNATGAARYTNAAYACNGAY TTYAARCCNCCNAGYGAYTAYAARCCNCCNGTNGTNMGNGTNAAYGAYAARGTNATGATH CCNCARGARGARCAYCCNGARATHAAYTTYGTNGGNYTNYTNATHGGNCCNMGNGGNAAY ACNYTNAARACNYTNGARAARGAYACNGGNGCNAARATHATHATHMGNGGNAARGGNTCN GTNAARGAYGGNAARATHGGNMGNAARGAYGGNCARCCNYTNCCNGGNGARGAYGARCCN YTNCAYGCNTAYGTNACNGCNAAYAAYCCNGARAAYGTNAARAARGCNGTNGARCARATH AARGARATHATHAARCARGGNATHGARGTNCCNGARGGNCARAAYGAYYTNMGNMGNCAR CARYTNMGNGARYTNGCNYTNYTNAAYGGNACNYTNMGNGARAAYGAYGGNYTNCARAAR YTNMGNCARATHGCNGARAGYCARACNATHGTNACNAAYACNATHGTNTGYACNATHTGY GGNGGNACNGGNCAYATHGCNCARGAYTGYAARCARAARMGNCCNGGNGAYTCNTTYMGN ATGCARCARATGCARAAYCCNGCNGAYMGNGCNAARATGGAYAGYGARTAYATGTCNYTN ATGGCNGARYTNGGNGARGGNCCNCCNCCNCCNAARTCNGAYAAYCAR------GGNCCN ---AAYTTYGGNCARAAYCARCCNCCNTTYAAYMGNCCNYTNYTNTCNAAYCCNCCNCCN AAYCCNATGGCNATHAAYCCNCCNTGGCARATG---CCNGGNAAYMGNCCNCCNATGTCN AGYCCNGTNCCNCCNCCNCCNTCNAGYTCNGGNCCNCCNYTNYTNAAYMGNCCNCCNATG GGNATGCARTCNACNGCNCCNCARATHAAYCCNATGGGNMGNYTNCCNATGCCNYTNATG AAYAAYCARGTNCARTCNCCNGCNGGNATGCARCCNCCNCCNAAYATGYTNCCNCCNCCN CCNGGNCARCARCCNCCNCARCARATGGGNAAYATGCARCARYTNCCNCCNCCNCARCAR CCNCARCARCARCARCARCAYCARCAYCARCAYCAR---------------CAYCARCAY CARCAYCARCAYCARCARTCNYTNMGNCCNTGGCARCARCCNGCNAGYCARGCNCARTCN ATHATGAAYCARGGNGGNATHTCNTCNACNGCNAGYATGGGNATHCCNCCNCCNCCNCCN TCNATGATGAAYGCNCCNCCNCCNCCNCCNGTNAGYACNCARGGNCAR---GTNCARCAR GCNCCNCCNCCNTGGATGCARCARCARCARCARCARTCNGGNAAYATGGGNYTNCARCAR CARCARCCNCCNCCNCCNCCNCCNCCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNACNTAYGCNGTNAAYYTNAAYATGGAYAARAARAGYATH MGNACNGCNATGGAYAARGCNTTYYTNGARYTNMGNAARAARGGNACNGAYGTNTGGGGN GARGAYMGNTTYTAYGTNCARYTNCCNACNGARGARGCNCAYGAYTAYCAYGARTCNTCN GGNTCNGTNCARCCNAARCCNGARCARGARGARTTYGTNYTNTCNGGNMGNATHCAYCCN MGNGTNYTNGARAARATHMGNTCNYTNGTNGCNTCNGGNGARACNAARYTNTAYGCNATH MGNAARCARYTNMGNAARTTYGTNGTNMGNGARYTNTAYMGNGGNTCNMGNCARGCNCCN GARMGNCAYGAYYTNACNGTNTTYCCNACNGTNAAYGAYYTNAARAAYCAYATHCAYCAR GCNYTNACNGAYATHGAYAAYGGNAAYYTNGGNYTNTCNCARCCNGAYTCNACNATGGAY ATG---------------TCNACNAAYGGNTCNGAYTGYGARGAYAARGAYGTNMGNCCN GAYYTNTCNTCNYTNTTYTCNGGNACNGCNATGCCNGARACNGTNACN------------ ------------YTNGARATGGAYGARAAYGAYAAYAGYTTYCCNTGGGGNYTNATHCAY CAYAAYGARYTNGCNACNATGYTNAAYACNGGNYTNGGNAARACNATGGTNATHGAYAGY MGNTCNTTYYTNGARTAYAAYACNAGYAAYATHCARCARTCNGTNAAYGTNTGYTGYTCN AARYTNGTNAARMGNMGNYTNCARCARGAYAARGTNCAYGTNGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY CCNYTNACNATGGARCAYYTNYTNGARCARCARTGGGARGCNGGNGCNCAYTTYYTNATG GARCARAGYGAYCAYTTYGAYATHTCNTCNYTNYTNAAYTGYYTNCAYCAYTAYAARTCN GAYATHMGNCARYTNGARGAYGARGTNMGNGAYYTNACNTCNCARMGNGAYCAYYTNATG GCNATHAAYGCNMGNYTNTCNATGGCNGGNGGNMGNMGNATHYTNTCNMGNATHCARTCN AAYGGNCCNTAYTCNTCNGCNGGNAARGGNTCNGGNAGYGGNGGNAGYCAYGGNCCNGAY GAYMGNGAYGGNAAYATHGTNCCNYTNGCNTCNATGGTNGTNYTNCCNAARCAYAGYCAR YTNCCNGAYATHCCNGGNGAYGGNAAYYTNTAYTTYGARTGYATGYTNTTYGTNTTYGGN ATHATHATGATGTGYYTNCARTAYATHAAYYTNTAYAARACNGTNTGGTGGYTNCCNCAR TCNCAYGCNCARTTYGCNYTNAAYTTYTAYYTNATHGAYTTYAAYYTNGCNGCNYTNATH TGYGTNATHYTNATHATHMGNTTYYTNATHTGYTTYGTNCARGARGTNCAYAGYAAYMGN ATGYTNTAYTGGCCNYTNTTYTGYYTNAARACNTCNATGGTNGGNTTYTCNGTNATHGTN ATGGTNTAYACNGGNTAYAARGTNATHATGGARCAYGGNGTNGTNACNAGYYTNTTYYTN TGYTAYCCNGCNGTNATHTAYGTNGTNYTNTTYGGNYTNGCNATHAARCCNYTNTAYCAR MGNAAYCARGCNTGGCCNMGNCCNGCNTAYGGNATGGAYMGNCCNGCNGGNCCNATGMGN ATHAARATGAARGAYGAYTCNCCNYTNTGYCAYACNTGYACNYTNACNCCNGAYATHGTN MGNGARGARGTNGAYGTNYTNAARMGNGAYTTYAAYAGYMGNYTNAARCARATHYTNTTY AAYTCNYTNACNACNTCNTTYTAYGCNACNGGNGTNCCNGTNTGGTTYTCNCAR---AAY ACNYTNTAYTAYGAYTCNTGG--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AGYGAYGAYATHTAYGCNGAYGGNGTNTCN--- GAR---GAYYTNACNMGNTTYGAYTGGTTYCAYGGNGAYATHGAYMGNGARGARGCNAAR AARMGNATHAARTCNATHGGNAARGTNGGNACNTTYYTNATHMGNACN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CCNTAYATGACNTCNCCNGGNCCNGCNGARTCNGAYAAYAAYACNTAY TCNCAYTAYMGNCAYMGNTTYTCNATGCCNTTYACNGARTGGCCNATGACNYTNGAYMGN ATGTGGTAYAGYYTNGAYATHGGNCCNGTNCAYYTNATHAGYTAYTCNACNGARGTNTTY AARGCNGAYGGNAARTAYGCNCCNTCNCARAAYAAYTGGYTNATHAARGAYYTNAARGTN GCNAAYGARAAYMGNGARMGNACNCCNTGGATHYTNGCNTTYGCNCAYGAYCCNATGTAY TGYTCNAAYAARGAYCCNGGNYTNACNTGYAARAARGARAARTCNAARATGGCNCARAAR YTNGARGAYATHYTNTTYCAYTAYGGNGTNGAYGTNATHTTYTCNTCNTCNGGNYTNGGN AAYGARATHTCNTAYCCNYTNTAYAARGGNTTYAARGTNGGNGAYAGYTTYAGYCAYCCN ATGGCNCCNGTNCAYATHAAYYTNGCNTCNGCNAGYCCNTGGAARGCNGARTAYAAY--- ---TCNTCNCAYGARGAYTGGYTNCAYTAYTCNGAYGAYGARAGYACNCCNATGAAYTTY GGNMGNGTNCAYATHGTNAAYGCNAGYYTNYTNMGNTTYGARATHGTNTCNTTYGARGGN TAYAAYGTNYTNGARTCNGTNGARATHACNCARCCNCAYCAYGGNYTNTTYTCNAARGAY GARYTNCCNGCNAAYGTNTCNGCNAARATHGAYAARGARATHCARATHTCNGGNGGNAAY CCNGGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GTNGTN GARGCNGARTCNGCNGTNGTNYTNGAYAAYCARAAYCCNGAYGTNTAYTGYATHMGNGCN YTNGTNMGNAGYTGYMGNAAYGARGAYACNYTNGCNYTNAARGAYYTNGAYCARGCNYTN TCNTTYAGYCCNAARCAYGTNAGYTGYYTNGTNGTNMGNGGNGCNATHACNMGNCCNTGG TCNCCNAARTAYCCNGGNGAYATHCCNMGNYTNAAYAARTAYYTNMGNAARGCNGARAAR YTNAAYCCNGAYTCNCARTCNTAYTTYAAYGTNGAYAGYTTYAAYCAYCCNTGYGTNCAR GAYTTYTAYGAYMGNATGYTNTTYACNYTNYTNGTNCCNCAYACNATGACNGARATHAAY YTNACNCCNGAYAARCCNAGYAARAARCARATHGAYTCNAGYCCNGARCARTTYMGNTGY GARTCNGGN------------------------TCNCCNACNMGNATGGGNTCNCCNACN GARAARYTNGAYCCNTTYMGNTGYGGNACNCCNTCNATHGGNGARAAYMGNCAYTCNACN MGNMGNMGNYTNGAYTAYGGNGARGCNGTNMGNAARCAYAAYTCNMGNCCNAARACNGCN TCNGARTAYATGGCNGTNYTNGARAARGARMGNMGNAARMGNATGGARGCNTCNGCNMGN GTNCARTCNGCNMGNAARATHTCNYTNGARAGYMGNAGYGTNMGNTTYAAYACNTCNTCN CCNGCNTAYACNGARMGNAAYTCNAGYGGNMGNACNACNAARACNMGNAGYACNAARGCN TTYGTNTTYGARACNCCNAAYAAYTAYTCNATHCCNGTNTTYCARCCNATGAAYATHGCN GARGCNCCNMGNATGTAYTAYMGNCCNTGGMGNGGNGAYAARYTNCCNATHGGNGARGTN CCNCAYCCNCARCCNTCNCCNGCNTTYTAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNGCNYTNACNACNGARAGYAGYCCNTCNAAR ACNTAYYTNTTYGARGGNYTNGTNGGNAARGAYMGNTCNMGNGTNTGGGAYCAYATGCAR TTYTGGGARGAYATGTTYYTNGAYGCNGTNGCNCARGARMGNGAYATHATHGGNATGGAY CARMGNCCNTCNGARATGATGGARMGNTAYGARTCNYTNGGNGAYYTNGARMGNAARMGN YTNGARTTYGAYGARGAYTGYGTNYTNTCNACNATGYTNTTYAAYCARGCNGCNTTYATG YTNATGATGMGNGTNCCNAARGCNGARATHAARAARAARGTNMGNMGNYTNATGGGNAAR TCNCAYATHGGNYTNGCNCAYAGYCARGARATHAAYAAYYTNYTNGAYAAYYTNCARAAY YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GCNYTNATHCCNAARGCNCAYMGNYTNTAYTTYAAR TGYTCNGARTTYCAYGARGAYTTYMGNTTYAGYYTNAGYTTYATHGARAAYTGYACNGAR ATHCCNGTNTCNMGNTCNYTNTGYGARAARTCNTGGCARTTYMGNAGYMGNYTNAARMGN AARAAYAGYACNATGMGNATGGGNTGYATGGARYTNGARGAYGGNATHTCNGCNATGATH TCNYTNGTNTCNYTNCCNGCNYTNGGNGGNAAYGGNAGYACNGTNGARAARYTNMGNACN YTNACNGARCARGGNGAYGAYYTNAAYGARGGNTGYTAYATHATG--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYGGNGTNGCNAAYGCNATHGGNGCNGCN YTNAGYAARATHTCNGCNAGYGTNGAYACNATGGTNAAYYTNATGGAYYTNATHGAYGTN AGYYTNATGGAYGCNAARATHAARGARGCNAARGARAGYYTNGARTCNCCNTCNGAYMGN GAYATHAARMGNGCNATHGARAARGCNAARAAYCCNTTYCAYAARMGNGCNMGNGARCAR GCNATHGARGGNGTNTGYGARCARGCNAARTCNGARGTNATHMGNCARGGNGCNAARGAR AARGARATHGARGTNYTNGARAARTCNGAYTCNGTNYTNGCNTAYATHGARGGNMGNGTN ---AAYATHAARGTNAARGTNGTNGGN---------------GARATGAARCARCARGAY GTNYTNAARGTNTGGGTNGARCCNGARGARGTNCARAGYYTNYTNGARATGAARGAYATH CAYCAYGTNAARCARAGYATHACNTCNACNGGNGCNTCNYTN---TTYGGNGARTCNGAR AAYGARAAYGAYTCNACNCARTAYCCNAARGAYCCNGTNATHGAYGAYAARTCNGGNGAR TGGATHYTNTCNGAYTGGGAYATHGARTGYYTNGCNGTNGGNTCNGGNATHTAYGGNTGY GGNGGNGGNGGNAGYATHCAYTTYGGNMGNATHMGNGCNYTNAARGCNYTNMGNAAYGGN AARAARATHMGNGTNGTNMGNCAYGARMGNYTNTTYAARAAYAGYGAYCCNGARMGNGAY YTNATHTTYGTNGTNGCNCAYYTNGGNTCNCCNACNGTNGCNTAYGARACNGGNATHTCN ATHMGNGARCCNGGNGARGCNGTNAARTGYYTNAARGARATHTAYGAYATHGGNCAYTTY AARGAYGGNAAYATHCARAAYGAYGARGGNATHTCNGTNGARACNAAYGARGARGGNTGY MGNTAYATHACNAAYTAYAAYCCNGAYACNTCNAAYAARAARGGNAARTAYAARATHATH GGNYTNACNTCNTTYGARTTYGCNGGNATGAAYGCNATHGARCCNYTNYTNYTNGCNGCN GAYATGGAYYTNCCNYTNATHGAYTCNGAYGGNATGACNMGNGCNTTYCCNTCNYTNGAY ATGTAYATHCCNTTYATHTAYGGNAARACNCCNTAYCCNYTNTCNATGGTNGGNAAYGGN AAYYTNTCNGARMGNAAYGTNYTNYTNTAYACNCCNGARAGYAARTAYGCNGARTAYTAY YTNMGNGAYGTNAGYATHAARCAYGGNTGYATHGGNAGYATHGCNYTNGCNATGACNAAR CAYGARATHGARACNAARGCNGCNCCNGAYGTNGTNAGYAGYGCNTGGMGNYTNGGNGAY GCNGTNYTNMGNGCNMGNYTNGAYAARMGNAAYGTNATHGAYGCNATHGTNGARYTNGAR AAYGGNAARCAYATHATHGTNGGNAARGTNGTNGAYGTNAARAARGARACNAGYGGNGGN TTYAAYAARGGNGAYGTNYTNATHGAYGGNGTNGARGARTGGTCNGGNMGNAARATHGAR ATGGARTTYCARAAYGARTAYYTNGTNGTNTTYCCNYTNGARGAYGGNMGNMGNGGNCCN TGYGARGGNTGYGTNCCNGAYYTNATHTGYGTNGTNGAYTCNGARACNGGNGARCCNATH ACNGCNGARGARYTNMGNTAYGGNATGATGGTNGCNGTNGTNYTNYTNCCNTCNTGYGAY YTNYTNMGNACNCCNGARGCNYTNAARTAYGTNGGNCCNAGYGCNTAYMGNTCNGAYGAY GARGTNTCNTTYGTNCCNTGGMGNGARMGNAARCCNATHCARCCNATHCCNCCNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARAARGCNGCNMGNAGYGCNTTYTCNAGYGCNTGGGTNTCNCCNCCN TCNTCNCCNCCNATHTCNACNGGNAAYTCNATHGCNCARATHACNCCNGGNGGNACNATH AAYYTNGTNYTNTCNGGNGTNGCNAGYCCNAARTCNCCNACNAAYCCNGGNACNTTYACN ATHACNCCNCCNACNGAYATHACNACNTCNTCNGTNTCNGCNGCNATHCCNGCNAGYACN GCN---------------GTNAAYAARCARAARAARGTNCCNCCNCCNCCNCCNCCNMGN AARGGNAGYMGNCCNACNTCNATGACNGGNYTNGAYYTNAAYGGNGCNYTNCARCARCAY CARYTNCARGARCARCARGAR------ATGCCNCARTTYGTNGGNGGNATHYTNGGNCAR CAYMGNYTNTCNGGNGGNCCNYTNTCNTCNACNCCNAARCCNTCNTCNCAYCARAARGCN YTNTCNACNTTYGARAARGAYATHGCNTCNGGNATHTAYGCNAAYYTNAAYMGNCCNGAR TTYCARAGYCARAAYACNTCNCCNCARCARATGATHGAY------AARGCNAAYTCNAAY AARAARGCNAAYAAYGGNAAYGTNAAYCCNYTNGCNCCNATGGTNTCNTCNAAYTGYGTN GAYMGNACNGARMGNGGNAGYAGYAGYGARAGYTCNTCNAGYAGYTCNGGNACNAGYATG GGNTCNCARCARTGYGTNGCNGGNGTNATGMGNTCNGCNTCNYTNMGNAGYTCNGGNAGY AARCCNAARCCNGARCCNCCNAARMGNCAYTCNAGYYTNYTNTCNAARAARGAYATHTCN CCNACNAARATGAAYGARAARGAYAARTGGTAYAAYYTNAARGCNGGNYTNTTYYTNACN TCNATHACNGGNTGYTCNGTNYTNGCNGGNTTYGGNYTNACNYTNGGNATGGCNAARAAR ACNGAYCARMGNCAYTTYGCNAARGGNYTNGTNGGNTCNAARGARYTNCCNGARAGYGGN GTNGCNYTNGCNACNMGNGCNYTNGCNMGNGCNTCNYTNTAYACNGTNACNGGNTTYGGN YTNTTYTGYTTYGCNGTNTGGAARATGATGGGNGTNCAYAAYATGACNGARTTYMGNGAR AARGTNGGNAAYGCNYTNCCNMGNGTNAARMGNAARGARAGYACNGGNMGNAAYGARTTY GCNACNATHMGNGAYYTNTTYCARTAYATHATHGAYGARGAYGARAARGCNAARGCNYTN AARGCNGARAARGAY--------------------------------------------- ---------------------------------------------------------GTN AGYACNATHCARYTNYTNYTNAARGARTCNMGNCAYGARAAYGTNAARYTNAAYMGNCAY GTNAARGCNYTNGARGCNGCNATHTCNATHYTNCARAARMGNYTNGAYAARAAYGGNYTN TCNGTNAGYGTNAAYATHCARGARGCNGARYTNTTYGTNCCNGGNGCNTCNAARCARACN TTYGAYAAYYTNGCNAARGARACNGCNMGNYTNMGNTCNYTNYTNAARCARGARAAYGGN YTNYTNGGNAARCARTCNGCNGAYGARATHGARGAYATGMGNGGNGCNYTNGARGARGCN GAYTCNGARAAYAAYGARYTNAARAAYAARATHAARGAYATGGARGTNATHAARYTNAAR YTNGTNAAYGAYTAYGARCARGARGAYAARAAYAARTTYGARAARGARYTNAARGCNMGN GARGCNAARCARYTNAARGGNGARGARMGNCARACNTTYCCNGAYCCNGGNACNATHCAR GAY---YTNAARAAYTTYTTYGAYCARACNATHGARMGNTGYAGYAARTTYAARGARCAR YTNCCNGCNAGYTTYACNGGNATHCCNGAYGTNMGNGCNGCNGCNGAR---AARTCNMGN MGNTTYTCNGTNTCNCARGARGAYTAYGAYYTNYTNGTNTCNAARCAYMGNGARGCNGTN ACNATGAAYCARMGNTGGCARATGTAYAGYAARGAYMGNGARCARCARATHCARGCNYTN AAYGAYMGNYTNAARGAYYTNTCNGAYCCNCAYCARATGACNGCNATGATHGARGARGCN TCNAAY---------CARAARATHGCNCCNYTNACNATGCARYTNMGNCAYAARGAYGAR GARATHYTNGARYTNMGNAARCARATHACNGGNYTNTCNAARYTNGARAAYATGMGNAAR GGNCARTTYGARYTNCCN------GAYAAYAGYACNGTNGARATHYTNAARCARCARATH CARGTNTGYACNGARGAYTTYAAYACNGARMGNAARGAYMGNGARCARGCNGTNCARAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TGYTAYGGNTGYCARTAYATHACNTGYGCNGAYAARTAYGAYATHGTNAARAAYGCN GAY------CAYYTNGGNGARTGYGAYGAYGAYCARTAYTGYGTNAARTAYAARACNATH GTNTGGATHMGNAAYTCNGGNGARATHATGGGNAAYTCNAARGARTCNCAYGTNGTNACN MGNTCNTGYGARTCNAARAARGGNCARAARGARGGNTGYGTNGGNTGGMGNAAYAAYGGN GGNGTNACNATHAARTGYTGGTGYGGNTCNGAYGGNTGYAAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARCCNACNYTNTCNTCNYTNAAYGAYYTNTCNACNAAY AAYATGACNAGYACNGAYGTNGAYGTNAARCCNAGYCARAARYTNYTNGARCARYTNACN CAYAARAARTAYTCN------------------------GGNGCNTCNTTYCCNGGNAGY AARACNAARGGNCCNCAYTCNATGAGYCARGARATGTAYGCNTGGAARYTNAARAARYTN AARAARACNATHAARGAYCAYATHTTYYTNAAYGGNGCNATHTGYGAYGARGTNYTNMGN ACNGARGARAARYTNGCNMGNGTNAARGARGARMGNMGNTTYYTNYTNMGNAARYTNYTN CARTTYCARTCNYTNAAYGARTCN---ACNGGNATHACNAARGCNGAYACNCCNGCNGCN ATGGTNMGNAAYYTNAARGCNGCNGTNGCNCAYAGYGARAAYGCNGCNTCNGCNACNCCN GCNAARGGNTCNAARGGNGTNAARMGNAARYTNAAYGCNTCNTCNGCNGGNGGNAGYGGN GGNCARGCNTCNGGNGCNGGNATGAAYATHGTNACNTCNYTNCCNACNYTNTCNTCNGCN TCNGARAARAARAARAARCARCCNCARTCNGCNAARGAYATHYTNGAYTCNYTNCARGGN MGNCCNAARAARAGYAARTCNGCNGGNAARAARACNATHCCNCCNYTNATGYTNGAYTCN YTNGGNMGNCCNATGATHCCNATGATGYTNGGNGAYATHACNYTNCAYAGYATGGGNGAR ATHGTNACNGAYMGNTCNAGYTTYCAYTGYCCNGARGCNATHTTYCCNGCNGGNTAYTGY ATHACNMGNGTNTAYATHAGYYTNCAYAARGCNGAYTCNAARTGYYTNTAYACNTGYAAR ATHTCNGARGGNGARAAYGARCCNYTNTTYGARATHGCNCCNGARGAYAGYTCNGAYATH GTNTTYMGNGCNAAYAAYCCNTCNGARTGYCAYAGYYTNYTNYTNMGNGCNGTNAAYAAR TCNMGNGGNGCNGAYGTNGTNCCNACNGAYACNCARGGNYTNGAYTTYTTYGGNYTNTCN CAYTCNGTNATHCARAAYYTNATHCARTCNATHCCNGGNGCNMGNAARTGYTCNMGNTAY AARTGGGTNAARTTYGARATHGAYAARACNGARTCNAAYGARAAYTTYGCNGTNGGNAAR AAYGAYCCNACNATHAGYTAYGARGCNTTYYTNAARMGNYTNGCNGCNYTNACNCARGCN MGNCCNGGN---YTNGCNTCNCARATHGARAARTCNACNAGYYTNMGNTCNYTNYTNACN AAR---------ATGAAYTTYAAYGTNGARYTNGTNYTNGCNTCNGGNGGNMGNYTNGGN MGNATHGTNCARATHGCNCAYGGNMGNACNGTNGCNYTNGAYACNCCNATGTGYACNYTN TTYACNAARGGNGGNAGYGCNCCNTAYYTNAGYYTNAGYATGYTNGARAARGTNAARAAY GTNCCNGARATHGCNACNATGAGYATHAAYTCNTTYGTNGARCAYGTNGAYAGYYTNMGN GARAGYGGNMGNMGNYTNGCNGARTTYACNTCNATGAARAAYAARYTNGTNYTNTCNACN YTNCAYGAYGCNAGYYTNCCNYTNCARTCNGGNAARAAYGAYAARTCNGGNGTNGCNGTN TGGGGNAARGGNGGNAARACNATGYTNGAYCCNGGNYTNTAYATGAARATHCARGARACN YTNCARCCNGAYTGGATHYTNGCNYTNAGYGAYGGNGAYACNGAYAARGAYAGYACNGAR AARMGNTCNAGYAARGCNGTNGAYMGNACNYTNGAYTTYYTNGAYAGYATHGTNTCNACN ATGAARAARTCNGARGTNYTNAARAGYTCNAGYYTNATHGGNACNGTNGTNGGNGGNTTY AGYGARMGNCARMGNCARMGNAGYGCNACNGARACNGCNACNMGNCCNGTNCAYGCNTTY YTNYTNGARGGNTTYCARAARGGNAAYTCNGARGARAAYATHGTNAAYGAYGARTCNTTY CARAARYTNYTNACNAARACNYTNAGYCAYYTNCCNGARACNAARCCNMGNYTNATGGAR ACNCCNTGGTCNCCNYTNCARGTNACNCARGCNGTNAARYTNGGNATHGAYGTNTTYTCN AGYGCNTAYCCNCAYACNYTNGCNGARAARGGNYTNGCNATGGCNGARGAYTTYMGNYTN CCNCARAARACNGGNGARGTNGARAAYGAR---AARAARGCNGAYACNAAYACNACNACN CARTCNTCNACNATGGAYYTNAARGARAARMGNTTYTTYGARGAYTTYACNCCNGTNYTN GARGGNTGYCARTGYTAYACNTGYGCNACNTTYACNMGNTCNTAYATHCAYCAYYTNYTN AAYACNTCNGARYTNYTNGCNCAYGTNYTNYTNACNATHCAYAAYTTYGARCAYTAYTTY YTNTTYTTYCAYTCNYTNMGNGARGCNATGMGNACNGAYMGNYTNGARGARYTNGARACN ATGYTNTCNAARCARGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TAYCAYTAYYTNCCNACN ACNGGNGTNMGNGCNGAYTTYAARMGNYTNATGAAYGARTTYATHTCNGCNCARACNGTN MGNTAYGARCARTTYAGYCARATGTGGMGNAARMGNMGNTTYGGNTTYYTNTGYGCNGGN MGNCAYTCNGAYMGNGARACNMGNGARTTYYTNGARMGNGCNYTNYTNATHGCNATHGAR TTYTTYYTNCCNCCNTAYCARTTYCARGTNMGNGTNGGNGGNYTNTAYYTNYTNTAYGGN ATHTTYATGACNCARCCNATHGCNCCNAARGTNAARGTNMGNYTNACNGTNAGYCARTGG GARGAYACNATHCARTTYCARCARGARGCNAGYGARCARAAYCAYYTNGAYGTNGTNTAY GTNTTYAAYMGNATGYTNGARGARCAYGCNTTYCARTTYTGYTAYACNCCNTGYGARYTN AAYGARMGNACNYTNAAYACNGARMGNGARGAYAAYGARGTNAAYYTNGCNGAYGAYATG AARGTNGARCARMGNGARATHGAYCAYYTNTTYAAYTAYGARTCNATGGARCARYTNTCN TAYYTNYTNAARCAYTAYCAYMGNATGAARGTNGGNATGGCNGGNMGNAARGCNACNAAR CCNGAYAARTCNYTNGAYGTNGTNCARGGNTCNATGGTNGARGAYYTNGTNGTNATGYTN CARTCNTTYAARGARAGYTGYTCNAAYATHTAYAARCAYGGNACN---------GCNCAY GCNGTNCCNTCNGARGARGCNGGNACNTCNGGNTCNGGNAAYAARMGNCARGCNATHAAR TCNAARATHTTYGGNGARGTNGARGTNMGNMGNGTNATHGTNTTYGTNGTNACNTGYGGN ACNYTNYTNYTNTCNYTNTTYTAYYTNCCNYTNYTNGTNAGYGCNGCNTTYGARTAYGGN ATGACNACNGTNTGYGGNTGGYTNAAYTTYTTYTGYYTNMGNGARGTNAAYAARAARAAR GCNGTNCARCAYMGNATHCAYCCNAAYMGNCARCAYTAYGAYGCNGTNGTNGTNTGGAAY GGN---AARGARAAYAARAARACNAARGGNAGYATHAGYTTYGAYGTNATHYTNAARCCN GCNGCNGCNGAYTCNCCNMGNCCNTCNYTNCCNGTNTCNCCNMGNAAYAAYATGCARAAR GARYTNTCNGARGARAARATHGCNATGAARYTNAARAARGCNGARCARMGNAARAGYYTN ATHGARCARGARMGNATGGARCARYTNGCNMGNGARMGNCARAARGCNATHGARGTNATH ACNAARGCNCARTCNGARAGYCARGARTTYTCNAARAARACNGARGARAARYTNAARMGN TCNATGGARACNMGNMGNGARAAYMGNGARACNCARATHMGNGCNYTNCARGARMGNYTN MGNGARCAYTCNGTNAARGTNCAYGAYGTNCARAARGCNGGNATGGARATGGTNAARGAY TTYGARACNAARGCNGARCARAARYTNACNCARAARATGGGNACNTAYGARGARAAYMGN AARAAYCARYTNTGYAAYATGYTNGCNAARYTNCARGARCAYGCNAGYCAYATHAAYGAR GTNTGYGTNGCNAGYGARAAYMGNAGYGCNAAYACNGAYGARYTNCARGARCARYTNGTN YTNAARATGGARAAYGCNYTNAARAAYMGNGARGARCARYTNMGNATGATHCARGAYMGN YTNGCNGARCAYGARAAYMGNATHAARGARGTNCARMGNAARAARGGNATGGTNTCNTCN GGNGARCCNYTNMGNTAYAAYTGYCAYYTNTGYTCNGAYTCNATGAGYTCNGARTTYYTN YTNMGNATHCAYYTNGCNAARCAYAARGGNTTYAARTAYACNACNACNGTNTCNACNCAR GAYGGNYTNYTNATHTGYGCNCAYTGYAGYTAYATHGCNCAYAGYAAYATHGAYYTNGTN GAYCAYGTNTCNAGYCAYACNACNGAYMGNMGNTAYAARTGYTCNYTNTGYAAYTTYGAR GGNCAYCAYAARAARGAYGTNGCNGTNCAYATHAARAARAARCAYAARGAYGARGCNAGY GCNAARGTNYTNGAYMGNGARAARMGNAARGGNAAR---ATGAARYTNAARGTNGTNAAY YTNAGYCCNGTNGTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GTNCCNATHGAYGAYGCNCARTTY GTNAAYGAYATGTCNMGNYTNATHAAYAAYAARYTNCAYAGYGAYATHCARYTNAAYATH AAYGGNAARTGYGTNTAYGGNCAYAARGCNATHYTNGCNACNMGNTCNTCNTAYTTYGCN MGNATGTTYGARACNAAYAARAGYGCNACNACN---YTNGARATHTCNAAYYTNACNTTY GAYGAYATHMGNATHGTNYTNCAYTTYYTNTAYACNAAYMGNYTNCCNATHGGNGTNTGY ATGAGYAGYYTNGTNACNATGTGYAARGCNTCNGCNATGYTNGARGTNCCNGARYTNAAR TCNGCNGCNATHTAYAAYYTNYTNGARTGGATHAARTGYGAYAAYGTNGTNGGNGTNTTY YTNCARGCNAARGAYGAYTCNCARYTNGCNGAYGTNAARTGYATHTGYCARACNTTYATG GCNTCNAAYYTNAARGARATGTCNAAYGARTCNTCNTTYAARYTNYTNTCNCARAGYGAY ATGGTNYTNGTNGTNCARGARGCNACNCARTCNYTNTGYATGAAY--------------- ---------GARCARGGNGARMGNYTNAARTTYYTNATHCAYAARYTNTGY---AARGAY CCNCAYCARYTNTTYYTNMGNYTNGARTCNCARGTNMGNGARGTNGTNATHGARATHAAR ACNGGNYTNYTNCARAARYTNAAYGARAAYGGNGTNCAYAAYCCNCCNTCNGCNYTNGAY TTYACNAGYGCNYTNYTNTAYCAYTAYGAYYTNATHACNAARAARGCNMGNYTNYTNGCN CARTAYYTNGGNGGNYTNACNGAYCAYYTNAARCARTTYCARGTNACNTGGGARYTNYTN AAYAARCAYYTNTTYCAYTCNATHGCNCAYAAYGAYCCNGCNATHAGYTCNGTNGGNCCN ACNATHYTNGARCARYTNMGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AGYGTNATHGAYYTNCCNCCNAAYATHMGNCAY CARTTYGGNAGYMGNGTNTGYGAYMGNYTNYTNTCNGAYCARGCNATHGTNACNYTNGCN YTNGARMGNCARMGNACNAARATGGGNCCNCCNMGNCCNTCNAARAARCARAAYGTNGAR GGNYTNCCNGTNGAYYTNCARAAYACNTAYGARAGYYTNGGNCAYACNACNMGNTGYAAY GTNTGYCCNGGNGTNAGYTCNGGNCAYAARATHAGYMGNACNAARGAYGARTTYAAYGAY GARGTNCAYCARMGNMGNGTNCCNAAYCCNGAYGARTAYMGNTAYCARMGNGAYGARYTN AGYATH---TGGGTNGARCARGAYGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AAYACNGGNGGN--------------------------------------- ------------------------------ACNGGNGCNGTNAARGAYTAYGCNGTNGCN YTNGGNAARTCNATHYTNTTYTAYGAYGCNCARMGNTCNGGNAARYTNCCNGCNAAYAAY CCNATHTCNTGGMGNGGNGAYTCNGCNYTNGGNGAYTGYGTNGTNGGNGGNTGGTAYGAY GCNGGNGAYCAYGTNAARTTYGGNYTNCCNATGGCNTCNTCNGCNCAYYTNYTNYTNTGG GGNGCNATHAARTTYAARGAYGGNTAYGTNAARGCNGGNCARATGGAYATGATGTAYGAY TCNGTNAARTGGGCNACNGAYTAYTTYTCNAAYGCNTGGAAYGARGGNGCNCARGARYTN GTNGTNCARATHGGNGAYGGNAAYGCNGAYCAYGCNTAYTGGGGNMGNCCNGARGAYATG AAYATGAAYMGNCCNTGYYTNAARATHAAYMGNGGNACNCCNGGNAGYGAYATHGCNGGN GARACNGTNGCNGCNYTNGCNGCNGGNAGYATHYTNTTYAAYGAYAARGAYAGYGCNTAY GCNAAYAARYTNYTNAGYAARGCNAARAGYYTNTAYGCNTTYGCNAARGCNCAYMGNGGN GTNTTYCAYGGNAGYGCNCCNTTYTAYGGNTCNTCNGGNGAYAARGAYGARATGTGYAAY GGNGGNGTNTGGYTNTAYMGNGCNACNAARAAYGCNCARTAYYTNAAYGAYGCNAARGCN AAYGCNGAYYTNGGNACNGCNTGGGCNYTNAGYTGGGAYGAYAARMGNATHGCNTGYCAR ACNYTNYTNTAYGARGARACNAARGAYAAYTCNTAYAARAGYGCNATGGARGCNTTYTTY AAYTCNTGGYTNCCNGGNGGNGGNATGACNTAYACNCCNTGYGGNYTNGCNTGGMGNGAY AARTGGGGNGCNAAYMGNTAYGCNGGNAAYAGYGCNTTYGCNGCNYTNGTNGCNGCNGAR GAYGGNGTNATGGCNGAYAARYTNMGNCCNTGGGCNGTNCARCARATHAAYTAYYTNYTN GGNGAYAAYMGNCAYGAYGGNGGNTGYTTYAGYTTYGARATHGGNTAYGGNTCNAARTTY CCNMGNCAYCCNCAYCAYMGNGGNGCNTCNGTNAGYGGNCARATHYTNCAYGGNGCNYTN GTNGGNGGNCCNGAYCARAAYGAYCAYTAYAAYGAYAGYCARGAYGAYTAYGTNATGAAY GARGTNGCNACNGAYTAYAAYTCNGGNTTYCARGGNGCNYTNGCNGGNATHGTNCAYYTN CARCARAAYAARATGTTYCCNTCNACNACNAAYAARTGYCCNTGY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TGGYTNTGYMGNGARYTNGGNAAR YTNGGNATHGAYTCNAAYGARGAYAGYGCNMGNTAYATHYTNTCNATGGARAGYTCNAGY GAYYTNGARGARTAYATGYTNGARYTNYTNGAYGGNTCNAAYCCNAARGTNMGNTTYTTY YTNCARGARYTNAARGAYMGNTTYTCNGCNAARGGNAARAARGCNAAYTTYCARGTNTAY MGNAARGARATGGGNCCNGARCCNTCNGARGARAARTCNAARAARAARAAYAARTCNGCN CCNAAYCARACNAARAAYAAYGGNAAYACNYTNAAYTCNAAYAARCARATHGTNAAYGGN AAYATHCCNGARAARTCNTCNGGNATGAARCCNGAYAARAAYTGYAAYCCNCARCARAAR ACNGGNGARATHGGNGTNGGNGCNAARAARAARACNAARTAYGTNCCNYTNTAYAGYAAR GARGGNCARGGNAARACNGTNGTNCARYTNCCNGGNMGNCAYAARTGYGARTGYCARGCN TCNMGNCAYAARYTNGTNAAYAAYTGYACNCARTGYGGNMGNGTNGTNTGYGAYCARGAR GGNGCNGGNCCNTGYATHTTYTGYGGNTCNYTNGTNTGYTCNCCNGARGARATGGARGTN YTNGAYMGNGGNACNAARAARTCNGARAARYTNMGNGARCARYTNATGMGNGARTCNAAR CCNAARGGNYTNAGYGARGCNGGNCARTCNYTNYTNCCNYTNGGNTTYAAY------AAY CARTCNAARGARGARCARGARAARGCNYTNAARCAYMGNGAYAARYTNYTNGARTAYGAY MGNACNAGYGTNMGNMGNACNCARGTNATHGAYGAYGARTGYGAYTAYTAYGCNACNGAY TCNAAYMGNTGGYTNAARAARGARGAYMGNGARAARYTNMGNAARMGNGARGARGARYTN MGNGARTCNMGNCAYGGNTCNMGNMGNAAYAARAARATHACNTTYGAYATHGCNGGNMGN AAYGTNMGNYTNYTNGARGCNGARGAYGAYTCNGGNAARAAYATGTAYAAYMGNGARGAY GCNGTNATHCARGARGTNCAYTAYGGNAARTCNYTNCCNAAYAGYGCNGTNAAYACNGAY YTNGTNAAYCCNYTNTTYGAYTTYGARCCNCCNACNTAYATGGAYACNGARCCNGTNAAR TGGGGNCCNGARACNTTYAARCCNGTNTCNGCNGARCAYYTNAAYCCNCARGTNTCNTCN MGNMGNATHCARGAYMGNGARYTNCARGARATGAGYGAYGARGGNATGTGYYTNAGYATG CAYCARCCNTGGGCNTCNYTNYTNGTNTGYGGNATHAARATGCAYGARGGNMGNTCNTGG TAYACNTCNCAYMGNGGNMGNYTNTGGATHGCNGCNACNGCNAARGTNATHGAYAAYGAY GARATHMGNGAYYTNGARCARTTYTAYAARCAYYTNTAYGCNGAYCCNAARYTNAARTTY CCNAARGAYTAYCCNGTNGGNTGYYTNYTNGGNTGYGTNAAYGTNGAYGAYTGYYTNGAY CARGGNCARTAYMGNGARAARTTYCCNGAYGGNGARTCNMGNTCNCCNTAYGTNTTYGTN TGYTCNAAYCCNTCNMGNYTNYTNGTNAARTTYCCNATGAARGGNMGNCAYAARATHTAY AARYTNGAYTCNCAYATHCAYCARGCNGCNAARAARGGNATHMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGGCNTCNCCNATHTAYCAYTGGTAYACNAARGARGTNTTYTAYTGGMGN AGYYTNGCNGCNACNYTNTGGTCNATHATHAGYYTNCCNATHYTNGTNTTYTGGATGTCN YTNTTYYTNAGYATHTCNYTNACNAGYCCNYTNTCNTGGGTNTCNGAYGCNGCNGCNGCN GTNTTYTCNGTNCAYTTYGTNTTYACNYTNATGACNTTYACNYTNGCNGTNGTNTCNGTN ACNTGGTTYTCNYTNTCNTAYATHACNGTNACNCCNGAYATHATHCCNTCNMGNYTNTCN TGYGTNATGGGNYTNTTYMGNTGGTCNMGNYTNCCNYTNATGGTNATHTGYGTNYTNATG GGNTCNYTNACNGCNTGGACN---------GGNATGGGNYTNTCNACNYTNACNGAYTTY GTNAGYACNGARGARTAYGARAARACNGTNYTNAAYGARAGYTGYYTNTTYGTNATHTGY TGYGGNATGTTYACNGGNYTNTGYTAYTAYTGYCARTTYTTYGCNMGNCARGARTTYTAY YTNAGYTTYCCNAGYATHCARMGNCARAARGTNTTYCARGTNMGNAGYGARACNMGNACN ATGGTNGARMGNACNGCNTGGCARACNYTNCAYGTNATHAARTAYCAYTAYATHYTNTAY TTYYTNTTYGGNTCNGTNCCNMGNGGNTGGATHTGYCARTCNTTYGGNATHTGYGARGAY ACNAARTCNTTYCCNYTNGAYTCNATHGTNGGNYTNATGAGYYTNTCNYTNYTNTGGAAR GCNTAYYTNACNTCNTTYGCNYTNACNTTYGCNYTNTCNTTYACNYTNGCNYTNATHMGN ATHTTYCAYTCNGARCARYTNGARYTNCCNGTNACNAGYYTNYTNGARGAYTGGMGNGAR MGNACNYTNTCNGAYGCNYTNGTNTGYTCNTAYTCNCCNYTNYTNCARCAYYTNGCNTTY TAYGAYATGGCNTGYYTNAGYAARGTNGTNTCNCCNMGNYTNCARGARYTNYTNAGYYTN AGYCARCCNGGNGGNCAYCCNAARGTNTGGATGTCNGTNAGYCARTCNGCNGTNTCNGCN ATHCARGARYTNACNAAYCARGTNAAYGARGARAAYTGGTCNATHYTNTCNAARGTNCCN ATHAGYCAYCAYCAYAGYCAYGCNAAYGGNGGNGTNGCNAAYGGNGGN---------TCN TCNGGNGAYMGNTGGGAYGGNGCNGCNGGNGTNCCNGAYYTNGTNCARACNCCNGGNGTN GARACNGCNMGNCCNGGNATHATGACNCARYTNAGYCAYMGNYTNTGYTCNYTNCCNYTN YTNTCNCAYYTNGTNACNCCNAGYCARGAYACNAGYAGYMGNMGNYTNTTYACNTCNTGY CARAARCARATHTGGGCNGTNGARAGYYTNTCNCAYATHGCNGTNMGNGCNTAYACNGAR GAYMGNTAYGGNGTNGTNCARACNTTYYTNCCNGAYATGATHACNGCNGTNYTNGAYYTN CAYGARGCNGTNGARAARCAYTTYAARYTNAGYACNTCNCCNMGNMGNCCNAAYAAYGGN TGYGTNCARGCNGCNGAYGGNYTNATHMGNTAYAARYTNCARTCNGTNYTNAARTCNTCN YTNTAYCARATGACNAAYACNTAYAARTCNCAYYTNCARGAYATHAARYTNMGNCCNGAR GARATHAARAARYTNACNCCNTTYATHCAYTAYACNYTNTTYGARGGNATHCCNTAYACN TTYTAYGARCCNGGNACNACNTAYTTYTGGGTNCAYTTYGGNYTNGTNATHYTNGGNTTY GTNYTNGCNGTNGTNACNTGYATHGCNCARTGGAARAARCCNGCNCCNTAYGGNAARCAY GAYTCNTCNGARGARAAYTGGGGNCCNYTNATHCCNCARMGNYTNTCNCAYTTYATHTCN GAYGCNATHCCNGGNGTNYTNATGTTYTCNYTNGTNTTYTTYYTNTAYAGYMGNGARGAR AGYGAYAARAARGCNYTNAAYTAYGTNTTYTTYGGNYTNTTYYTNGTNCAYACNATHCAY MGNGGNATHATHCAYCCNYTNATHATGAARTAYAARAGYGCNAARGTNTCNYTNGGNATH TGYATHGGNGGNGGNYTNCCNAAYGTNYTNTAYCARTGGYTNATHGCNAAYCAYATHGGN GTNGCNAARTAYGAYGAYTCNTAYCCNTAYGAYCCNMGNTTYATHGTNGGNGTNYTNYTN TAYGTNACNGGNTTYATHATHAAYMGNTGGGCNGAYTGGAARYTNMGNTCNYTNMGNAAR AARAARNNNGCNACNGARYTNGTNGARAGYAARGGNTAYTAYATHCCNTAYGGNGGNYTN TTYAAYTAYATHTCNTGYCCNAAYTAYTTYGGNGARYTNGTNCARTGGGTNGGNTGGACN ATHGCNACNTGGTCNYTNTCNGGNTTYGTNTGGGCNTCNTTYGGNGCNGCNACNTTYYTN GCNMGNTCNMGNCAYAAYCAYAARTGGTAYCARGARMGNTTYGARGAYTAYCCNTCNAGY MGNAARGCNYTNATHCCNTTYGTNTTYTCNGAYAAYGGNTGYGAYCAYGARGARTCNYTN TCNMGNACNGCNCARYTNGTNYTNAARGCNTCNGARYTNTTYTCNGAYACNAARACNAAY AARACNGGNYTNACNYTNGARGARGARATGGCNGTNTTYYTNCCNACNYTNAAYYTNTCN ATGGTNGAYTTYGAYACNGTNACNGTNGCNGAYYTNMGNCAYAARTTYGARMGNAARAAR MGNMGNAARYTNTCNCCNCARGARMGNMGNAARTTYTCNGARCARTGYCARACNTTYATG YTNAARYTNACNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------GGNTTYATHYTNCAYCCNTCNGGNACNCAYTAYATGCCNATHTCN GTNCAYAAYAGYAAYATHGCNGGNYTNTTYGARTCNAAYGGNGAYCARGARGGNATGCCN GTNTTYCAYCCNATHAGYATHCCNGTNCAYTTYMGNMGNCCNGTNATH------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TTYACNCCNGGNTCNAARGARACNTTYTTYATHAARGCN CCNCARYTNGGNAAYYTNGARATHYTNTCNATHGARCAYGAYGGNATGGARAARAARCAY GGNTGGTAYTGYGARAARGTNGARATHACNTGYATGMGNACNATGCARCAYTGGGTNTTY ATHTGYAARAAYTGGYTNTCNYTNCAYCAYGGNGAYTTYAGYYTNGCNMGNAAYYTNGAR GCNMGNTAYGTNGARAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ACNAGYATGAGYMGN GTNGAYATHGGNGGNATGACNTAYGTNAARACNGGNCCNCAYACNYTNGARYTNTCNTCN CARGGNAAYAARAARYTNGCNGCNAGYMGNGCNGTNCAYAARAGYYTNTCNATHGTNGTN GCNAARCARMGNAARACNGGNAGYMGNYTNAARACNAARCARAARCAYTGYGTNTTYTTY MGNMGNTTYGGNAARTGYCARMGNGGNGAYGARTGYCCNTTYATHCAYGAYCCNGAYAAR GTNGCNGTNTGYACNMGNTTYYTNMGNGGNCARTGYGAYAAYAGYTCNTGYCCNTTYTCN CAYGAYGCNTCNGTNCAYAARATGCCNGTNTGYYTNTTYTAYYTNCARGGNYTNTGYTCN MGNGARGAYTGYYTNTAYYTNCAYGTNAARGTNAGYCCNGAYGCNCCNATHTGYAAYGAY TTYMGNCARGGNTTYTGYCCNYTNGGNYTNAARTGYAARAARYTNCAYTCNTTYGTNTGY CCNTGYTAYGCNGTNTTYGGNAAYTGYCCNCARMGNGAYAARTGYTCNYTNYTNCAYMGN CAYAGYAAR---ATGCCNTTYTTYAARATHGARACNAAYYTNCCNAARGAYCARATHCCN GAYACNTTYYTNCAYGARGCNACNCARATHATHGCNTCNGARYTNGGNAARCCNGCNTCN TAYGTNTGYATHCARGTNTGYCCNGAYCARGTNATGAGYTTYGGNGGNACNACNGARCCN TGYGCNAAYATHACNYTNAAYTCNYTNGGNATHGTNGGNCCNGAYAARAAYAARTCNYTN GCNCCNGTNYTNTCNAARTTYGTNGARAARCARYTNGGNATHAARCARGARMGNTTYTTY ATHTTYATHCAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CARACNCCNACNAAYYTNCCNGCNTCNGGNYTNGCNTCNGGNYTN GCNMGNGCNTGGGARYTNTAYGAYAAYCCNAARGCNGTNATHGTNTTYATHGTNAGYAGY TTYGARMGNAAYGTNYTNGAYCARMGNGCNYTNGARTTYGCNGTNTAYAARMGNAAYCCN CARATHMGNGTNATHMGNAARACNYTNYTNGAYGTNGARGARAARGGNAGYYTNGAYGGN GAYAGYMGNYTNTTYGTNGAYGGNGAYGARGTNGCNGTNYTNTAYYTNMGNGAYGGNTAY ACNGTNGAYAAYTAYCCNTCNCARAARGARTGGGAYGGNMGNYTNAARATGGARYTNTCN MGNGCNATHAARTGYCCNTCNGTNCARTAYCARYTNGCNGGNGCNAARAARATHCARCAR GARYTNGCNMGNCCNGGNGCNYTNGARCARTTYATHGAYGAYCCNAGYGTNATHAARGAY YTNMGNTCNACNTTYGCNGAYCARTTYAGYYTNGAYYTNGGNCCNGARGGNGAYAARGCN GTNGCNYTNGGNATHGCNTCNCCNGCNAARTTYGTNYTNAARCCNCARMGNGARGGNGGN GGNTAYAAYATHTAYGGNGARGAYATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ACNGTNGAYTGYYTNYTNAARAAYGTNCCN GGNYTNGARGARAAYYTNMGNMGNGGNATHGAYGTNATHGARTTYGGNTGYGGNAAYGCN TAYCAYYTNTCNATHYTNGCNACNAAYTTYCCNAARAGYAAYTTYATHGCNACNGARGTN AAYCCNGARTTYYTNGARCCNYTNAARAARMGNTAYAAYCAYATHCCNAAYYTNAAYTAY GAYGTNGTNGAYGTNTGYAAYATHCCNGARATHYTNGAYAARAARTAYGAYTTYGTNTAY ATGAAYGAYGTNYTNCAYGAYYTNCCNCAYCCNGTNGAYGCNYTNAARGGNATGMGNMGN TTYYTNAARGGNCCNGARGGNGTNTGYGCNATHATHGAYATGGCNGGNACNGGNAGYCAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CCNCCNCCNTCNTAYGAYTCNYTNTAYGGNMGNGTNAARGCNGCNAARGCNTCNTCNGAY GGNAAYGTNGAYTTYTTYAARACNTTYATHGTNATHATHYTNTCNACNATHGGNTTYACN ATHATGYTNGGNYTNTTYATGGCNATHCCNGTNTCNATGATHGTNATGGGNGCNATHTAY YTNGAYGAYTGYAARGCNGARMGNATGATHCCNATHTAYYTNGTNGTNGCNGGNAGYTTY GGNTGYGCNAARAAYYTNTTYAGYYTNATHCARMGNTGYMGNAARTCNGARGARGARMGN CARGARGAYCARAARAARGTNCARCCNGTNGARGCNATHGTNAAYTGYTTYATHTTYGCN TGGTTYATHGCNGGNTGYGTNTTYATHTAYMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AGYGTNCCNGAYMGNGARCARCCNGCNYTNAGYCAYGAYMGNGGNGGN AGYAGYMGN---GGNCAYGCNCCNGCNGCNATHCCNCCNTCNGGNATGCCNTAYCCNATG AAYCCNCCNGTNGTNGGNGAYGGNGTNGGNTCNGGN---GGNCCNYTNACNGGNGAYCAR YTNGCNAARYTNMGNMGNGARYTNGARGTNGTNCARGGNAAYGTNMGNATHATGGGNGAR ATGYTNACNGARYTNAGYCCNACNGGNGTNGAYTCNTCNGAYYTNGARYTNYTNCARGAR YTNAAYMGNACNTGYMGNCARATGCARTCNMGNATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARTGYMGNCARCAY GARGCNATHGTNAARGAYACNCARTGGCCNGTNGTNTAYAGYTCNGARTAYAAYATHGGN TTYTGYGGNYTNGARAARYTNCAYCCNTTYGAYGCNGGNAARTGGGGNMGNATHTTYGAR TTYYTNAARGTNGCNGGNATGYTNMGNGARGAYACNGTNGTNGARCCNTTYGARGCNACN GARGARGARYTNYTNTTYGTNCAYACNAARMGNTAYYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ACNGGNAARMGNYTNATGGGNAARTGYMGNATGYTNYTNCARGAR AAYGARGARYTNGGNAARATGATHTCNTCNGGNMGNACNGCNMGNYTNGARGGNGARATH TCNYTNCAYAARGCNYTNGTNGCNGARATGAARAARAAYCARAARGARYTNGAYGARTTY GTNGGNGARYTNGARGARGAYGTNGARGGNATGCARGGNATGATHTTYATGYTNCARCAR CARYTNAARGARGCNMGNGARCARATHACNMGNYTNCARCARGARAAYGARCARYTNMGN ACNYTNCARYTNCCNTCNGARCCNGARCCNGGNGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TAYCAYGTNACNTTYGTNGAYGARCAYGTNTCNMGNGCNTGGGTN MGNTCNCAYYTNATHATHCCNTAYGAY------------CAYMGNTCNACNCCNACNGAY AARTCNMGNTTYTGYAARAARGGNYTNCARACNGCNGTNACNATHGCNGARMGNGCNATG AARYTNAGYYTNCARGAYMGNYTNGAYACNTAYAGYTTYGCNAARMGNTAYTCNAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CAR GCNTCNGTNAARAAYTTYCARATHGTNCAYGAYAAYGAYGTNGAYTAYATHGTNATGCAR TTYGGNMGNGTNGCNGARGAYGTNTTYACNATGGAYTAYAAYTAYCCNATGTGYGCNYTN CARGCNTTYGGNATHGCNYTNAGYAGYTTYGAYGGNAARYTNGCNTGYGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TAYAGYGGNMGNTCNTCNGGNTTYCCN YTNGAYGCNGTNCCNTCNGAYGTNTCNAARGAYYTNMGNAAYTTYATGAARCARTTYTCN AARGARACNYTNGAYAAYATHTTYYTNTAYGGNATHAARACNATGYTNCARGARTCNGCN MGNGGNGTNCCNGTNCAYGGNTTYAARYTNTTYYTNCARYTNATHTCNCAYACNAARTCN GAYACNGGNYTNGAYGAYATHCCNCARTAYYTNGARYTNYTNAARACNCAYCARAAYAGY YTNTCNAARTGYYTNTCNATHYTNTGGGCNYTNGGNCARTGYGGNAAYAARCAYTTYCAY TTYGGNYTNAARGTNTGGYTNGARYTNATGATGCCNACNYTNGARATHMGNCARGTNGCN CAYTAYCCNGTNGARTAYYTNGARAAYYTN---------TTYAARAARTAYTCN---AAY YTNCCNAARAARAGYTAYGGNYTNGTNTCNATGATHGARTAYTTYCARGTNYTNGAYGTN TTYTTYAGYCCNAARTTYGCNYTNGCNAGYGAYYTNAARAARMGNYTNATHACNGTNTAY CCNACNATHAARACNYTNGCNTAYGGNGARGAYCCNTCNCARAAYYTNMGNAARTTYTTY CCNTCNTAYYTNTCNMGNTTYGCNAAYGCNMGNTCNAARGARATGAARGARGARYTNYTN GCNTCNATGACNGARTGYYTNATHACNGAYAARCARTCNTTYGGNGTNTGGTGYCARYTN TAYACNAARTAYYTNCCNACNTCNAGYCAYYTNYTNGAYCAYATHAAYAGYAAYTGGTCN AARYTNTCNTCNMGNTTYGAYAARAARATHYTNMGNGARACNYTNMGNTCNTTYTCNGTN ACNAAYGARGARYTNGARGTNCARACNAARGGNAARCARAAYGGNYTNAARYTNTCNCAR ACNGCNACNAARGAYYTNATGATGAARYTNAGYGCNGCNCAYTTYCCNTGGAGYYTNYTN GTNTTYTTYATHACNTCNATHTTYGCNGCNATHGTNGTNTAYGAYATHACNTCNAGYCCN ACNTTYMGNTCNTCNAARACNATGCARTTYYTNGARMGNTAYGGNTTYYTNGCNYTNYTN GARAARACNTAYCAYGCNGTNCAYAAYATHTCNACNGTNTCNGTNAAYTGGYTNAARGTN AAYTTYCCNATHTTYTAYAAYCARGTNYTNGARACNGTNGTNCCNYTNTCNATHACNGTN TGGAAYAGYTCNMGNGAYTTYATHATHAAYGCNGARGTNCAYTCNMGNCCNTAYMGNGAR YTNGCNATGGARAARATGATHCARTTYTAYTAYTGGGTNTAYGAYYTNTCNCCNGARTTY TGGYTNMGNTGYGARGARYTNACNTGGYTNTCNTGGGAYYTNYTNAARGAYTAYACNTTY MGNATHTGGGTNCAYACNCARTAYTTYGCNGGNGARGCNCAYCAYTGGYTNACNGARCAY GTNYTNACNGGNTCNYTNTCNAARGARTCNATHAARGAYACNGCNYTNTGGGGNGTNGGN CAYYTNCARAAYTGYACNTCNYTNYTNGTNTCNTGG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AAYMGNACNAGYGGNATG ACNTCNGARATGGCNYTNGARAARYTNAARACNGGNYTNMGNGAYAAYCAYTCNACNTTY ATHTAYCAYTGYCAYAAYCAYTAYTTYTGYCCNGTNGGNTTYGARGAYTCNCCNYTNTAY CCNYTNGAYGCNTAYAGYGAYAARATGTCNGAYGAYTCNATHGARAARACNTGGATHYTN ATHGGNGAYACNAGYMGNAARTAYGGNCCNTTYCAYTGYAARAGYTGGGAYGARATHTGY YTNGAYYTNAAYTGYGARAAYCCNGARTAYTAYAAYATHMGNCARTCNTGGAAYGGNYTN ATGAARMGNCARAARAAYAARMGNATHGGNGGNAAYYTNCAYTGYATHATGTGYTTYCAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARGTNAARCARYTNGARGCNGARGAYYTNATGTTYMGNAAR CAYYTNGGNATGGARATHMGNAARGTNAARGGNGGNTGYYTNCARGTNGCNTTYAGYCAR ATHGAYCARAARCARCCNAAYTCNYTNTTYYTNTTYTCNYTNACNTTYGAYGARAAYMGN CARTAYGTNATHTCNGAYTGYAARCCNCCNATHTCNGAYYTNGARGAYATHGTNCAYAAR YTNAAYGCNGAYAAYGAYTTYMGNAARTTYGTNCAYACNATGMGNAARMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNAARMGNMGNTAYAGYGAYGTNYTNGAR---GAYYTNTAYMGNGGNCCNCARGAR TTYATGGARGCNGGNGTNMGNGGNTTYYTNGTNACNTCNYTNCCNGAYMGNGARGARCAY TCNATHGAYGARACNGTNAARGTNYTNMGNAARACNTGYGTNAARYTNTAYGGNGGNATH AARCCNYTNAARMGNGARGAYGCNTCNTTYGCNAARGGNTAYATHATGATHGAYTTYATG GAYCCNGARCARGTNGTNGCNYTNCCNCAYCCNGAYGCNGARAARAAYGCNGARGCNGAR AARGCNAARGCNGCNGARGARGCNGCNAARGTNGAR------------------------ ---------------------------------------------------------GGN GARGARATGGARCARGARAAYAARCARGARCARGARGARGARGCN------------AAR CCNGARGAYGGNGAYGCNGGNGGNGAYAARGCNAARGCNGARGGNGARGCNGARAAYACN ACNGARGARGTNAARGARAGYAARCCNAARGARGAR------------------------ ------------------------------AARAARAARAARGARGAYACNMGNMGNMGN MGNGAYGAYGARAARAARCCNYTNATGYTNGCNCCNTAYAARTTYAARGGNTTYMGNACN GARYTNMGNAAYATGATGTTYATHAARTCNGAYATHCCNGAYCCNGTNGARGCNGTNACN GCNTGYTTYGAYYTNATGYTNAAYMGNAARCCNYTNTAYACNGAYTGYGTNAAYCARYTN YTNCCNGTNCARGGNGTNTGYGAYAAYGAYTAYAARCARYTNGARATHATGTGYMGNMGN GTNYTNGTNCCNTAYATHGGNGARCARYTNGARGARCCNCCNAGYTTYGGNGTNATGYTN GTNAAYAARATGTGYGARCCNGGNGCNGARGTNYTNYTNGARGTNGTNMGNAGYGCNATH TGGTGYYTNAAYCCNTGYGCNTGGCARTGYTCNCCNTGGGCNGARCCNGAYGTNGCNATH CAYATHGARATHATHGGNAGYAARATHATHYTNAGYGCNATGCCNCAYTAYATGAARTAY MGNCARTAYAGYCCNTTYGCNYTNTAYGARYTNGGNCCNGGNAARCCNGARGAYGARGAR ------AARYTNYTNAARGARMGNTCNGAYGAYTTYMGNCCNMGNGGNTGYMGNGGNMGN MGNAARGAYAARAGYGGNMGNCAYAARGARCARGAYAARGGNGARAARAARGARGGNGGN GARAARGARAARGCNAAYAARGAYTCNGCNGARACNGGNGAYAARGAYACNGARCARCCN GARCARACNGARCARACNGAYCARACNGARGARGGNAARGARGARGAR------------ ------------------------------------------------------------ ---------------------------------------------GARMGNYTNAARMGN ATHAARMGNAARACNGARGARAAYATHYTNGTNYTNYTNTCNMGNATHTCNGTNAARACN GAYCCNTCNCARTAYYTNCCNAARTAYGCNGTNYTNTCNACNYTNACNAARTAYATHGGN GTNGTNCCNAAYCCNATHCARMGNTGYATHMGNACNYTNTTYMGNGTNTTYCAYAAYCCN CAYTGYTTYGARTCNGTNYTNYTNGARCARGCNCCNGCNYTNATHGTNAARAAYYTNATH ATGGAYCARGAYGGNAARTTYCCNTCNGTNYTNTTYAAYGAYCARCARGAYGGNGGNCAR AGYGGNCCNCARAGYMGNAARATHAAYTTYGAYGAYYTNTTYTCNTGYTCNCARAGYTCN GARACNCCNTCNGAYTTYGARATGCARATHCARTTYGARTTYGGNGGNGAYGCNTAYAGY AAYATGATHCAYCARMGNAGYTTYMGNTCNGAYATHTTYCARCCNAAYYTNYTNTTYAAR GGNAARTCNYTNAGYMGNGGNATGTCNMGNGAYACNTCNACNCCNGARGAYYTNACNMGN GTNMGNATHMGNAGYGGNATHAAYYTNATGAARGCNATHACNTCNYTN---------GCN YTNTCNMGNTAYGGNGAYGGNGARATHCARMGNATHTGGTCNMGNGGNACNGARTCNGAR AARYTNATGTGYGCNATHAGYYTNYTNCAYATGCCNATHGGNTGYGGNCCNYTNCAYMGN MGNCARATHGTNYTNAARCAYGAYGCNYTNCAYCARGTNATHCCNTTYYTNTTYTGYAAR GARGGNCCNGTNGTNMGNGARGGNATHGTNACNGCNYTNAGYYTNYTNGCNCAYYTNTTY MGNATHCARAARGTNACNCCNAARATHTGYAARYTNAAYACNTGYCCNGARTCNAAYCCN TTYAARMGNGGNAGYCCNGAYTTYCARATGTCNAAYAARATGAAYAAYGGNAAYGAYGAY ATHTGYMGNTTYGARCAYATHTCNGAYAARYTNGAYAAYTTYATHGTNGTNGAYAAYGGN GARMGNAARGTNTTYAARGCNTGYAARGARATHYTNATGAARAARTCNGARGTNTTYTGY GCNATGYTNGGNGGNGGNTAYGCNGARGCNGAYAARGTNGAYATHGARTTYTCNGAYGTN AAYYTNTCNGGNTTYGARTAYGTNYTNCAYTTYYTNCAYGGNTGYGARTCNGGNTGYGCN GTNATHGAYYTNYTNTCNTTYATHGAYTTYATHYTNGAYMGNTGYATHGAYATHGTNACN GTNGCNGAYMGNTTYYTNGTNCAYGAYYTNATHCARTAYYTNACNTCNGTNYTNTCNCAY ACNTGYYTNTAYACNMGNACNGTNACNGAYATHATHTAYGTNGCNTCNACNTAYAARYTN AAYTGYYTNGCNACNGAYTGYGTNGTNGAR------------------------------ ------------------------------------------------------------ ------------------------ATGCARAARYTNAARAARGGNATHTCNCAYGCNCAY AGYGTNMGNYTNMGNCARYTNAGYCAYATHYTNTAYGAYAARGTNACNGARATHATHAAY ACNGGNGARYTNTCNCARGARATHYTNGAYAARCAYGTNTCNATHACNGCNGTNAARATG ACNAARGAYATGAAYAAYGTNAGYGTNTAYTGGGARTCNGAYMGNGAYGAYTGGCARGAR GTNGARCAYYTNYTNYTNTCNCAYAGYGGNAARYTNMGNAGYYTNYTNATHTCNTAYCAY GTNYTNGGNMGNATHCCNCAYATHGTNTTYGTNMGNGAYAARTCN---GCNGTNAAYYTN CAYCARYTNACNGARYTNTTYAARAARGCNGAYTAYGGNCCNGAYGGNGTNGAYGAYAAY TTYGAYYTNGARCARGAR---------------------AARAAYYTNAAYACNACNCAR GAYGGN---------------------GGNYTNGGNCAYYTNMGNYTNCAYGAYGCNACN GAYGAYYTNAARTCNAARGGNGAYCARATGAAYGCNATHCAYAAYAARGAYAGYCARGCN GCNATHGAYTCNAARTAYGARACNTCNACNAARAAYGAYYTNCAYTAYMGNTGYGAYYTN TAYGGNYTNAAYMGNGARGARATGATGAARAARATHYTNGCNAARAARTCNAAYTCNMGN MGNAGYGAYGAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CARCARGARTCNACNATGTCNGARGARGTNGAYCAR CAR------YTNGTNGARAARYTNTAYMGNGARTTYCCNAAYACNACNAARGCNYTNATH TCNGAYATHYTNGTNGGNTGYTTYAAYAAYGARMGNGARGCNMGNGARCARYTNACNGAY YTNGGNTTYGCNACNAGYACNTCNCCNACNMGNAAYACN--------------------- ------------------------------------------------------------ ------GTNGAYTTYACNGARGTNGGNTGGGAYGAYTGGATHGTNGCNCCNCCNGGNTAY AAYGCNAAYTTYTGYGAYGGNGARTGYCARTCNCCNYTNCCNYTNTTYACNAARGCNTCN AAYCAYGCNATHYTNCAR---------ATHGARTGGGARCCNYTNGCNCCNYTNGGNCCN TCNGCNGCNTTYCAYGTNGGNTGYYTNATHMGNGGNAAYYTNTAYATHCAYGGNGGNATH TCNGAYATGAARTCNAAYCARCCNTCNAAYCARYTNTAYMGNYTNAAYYTNCAYTCNAAY YTNTGGCARTGYGTNMGNACNCCNGGNAGYCCNGCNYTNAGYCAYCAYGCNTGYGTNGTN AGYGARGGNMGNTAYATGATHYTNGTNGGNGGNTGGAAYGGNAARMGNMGNTGYGCNGAY GTNCAYATHTAYGAYTCNCARGARGAYAARTGGYTNCCNGTNAARCARACNGGNTTYCCN GARGGNGCNGGNYTNAGYTCNCAYACNGCNTCNATGYTNCARAAYGGNGAYATHYTNATH ATHGGNMGNGARGGNAGYYTNMGNYTNCARMGNAARCAYGGNCAYGCNTAYATHYTNAGY GGNAGYGTNYTNTCNGGNCARTTYYTNTAYMGNGARTAYAGYAAYAAYGTNACNTCNMGN TCNGGNCAYACNGCNGAYGTNATHAGYAAYTCNGTNTTYATHATHGGNGGNMGNAGYGAY AARYTNYTNGARAARGCNACNGGNTTYAARCCNCARCARGARCCNAARTCNTCNATHYTN TCNTCNATHYTNAAYGCNATHAARACNCARCARGTNAARCCNATGACNAARYTNCCNTGY GGNMGNAARAAYCAYATHACNGCNGCNGAYCAYTCNTGYATHYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARTTYGARGCNCARGARGAYGCNAARATHGCNGGNYTNAARAAR CCNCARCARGGNTCNMGNCARCARCCNATGGARGGNYTNATHYTNAARTTYACNAAYGTN GTNAARGGNTAYCARTAYMGNTGGYTNGTNYTNGAYCCNGARTCNGGNATGYTNGARTAY TTYGARAARGARGARCAYAARAARCARMGNCCNMGNGGNTCNGTNCAYYTNGCNGCNGCN GTNGTNTCNCCNTCNGARGARGAYTCNCARACNTTYATHGTNAAYGCNGCNAAYGGNGAR ATHTAYAARYTNMGNGCNTCNGAYGCNMGNGAYMGNCARYTNTGGGTNGAYMGNATHMGN TCNACNGCNGARCAYCAYACNGCNCAYATHGCNCARTTYCCNCARCAYTCNCCNAARYTN GTNMGNAAYGAYTCNTTYACNTCNCARCCNAGYMGNMGNCARGAYTCNGGNMGNMGNACN MGNGGNTCNATGGARAGYYTNCCNACNAGYAARMGNTCNCCNMGNGAYGARGCNTTYCAR GARGTNMGNGARTTYCAYYTNGAYGCNGARGAYTGYYTNMGNAAYYTNGARGAYAARATH TCNGCNYTNTCNCCNTCNGGNGARCAYATHAAYTCNYTNGAYTCNGARYTNYTNYTNYTN AARGCNACNTCNGCNGCNACNYTNMGNTGYGTNCARGAYTGYATHTCNYTNYTNCARAAY GCNGARAGYCCNCARTCNAGYCCNMGNAGYCCNATGGTNAAYGAYCARCCNMGNYTNAGY GTNACNGARACNGAYGGNAAYATGGAYTAYCARGCNAAYYTNCCNAARGARGARGARGAR GTNYTNGAYGARGARGTNTAYGARGAYAARGAYYTNGARGGNGTNGARGARCAYAARTCN ATHATHYTNCAYYTNYTNTCNCARYTNAARYTNGGNATGGAYYTNACNAARGTNGTNYTN CCNACNTTYATHYTNGARMGNMGNTCNYTNYTNGARATGTTYGCNGAYTGYATGGCNCAY CCNGARGCNTTYYTNAARATHCCNGAYATHCARGAYCCNGARGGNMGNATGYTNGCNGTN YTNGARTGGTAYYTNACNTCNTTYCAYAAYGGNMGNAARGGNACNATHGCNAARAARCCN TAYAAYCCNATHATHGGNGARACNTTYCAYTGYTCNTGG--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TTYGCNTCNTCNTTYGCNTTY ATHTTYTTYGGNGCNAARAARYTNTTYTGYTCNMGNGCNYTNAARTTYCARAGYAGYGGN ATHTCNYTNGARTTYCCNGTNYTNYTNATGACNGGNYTNTTYTCNATGCCNYTNGGNGTN YTNCARTTYATHCCNGTNTAYCAYCCNYTNCAYGAYACNYTNGGNATHCAYTCNGARGTN TGYGTNYTNYTNTAYYTNGGNTTYTTYGCNYTNGTNGTNTGGTGYTCNGAYMGNMGNCCN TTYGARTTYGCNMGNCAYAARGGNGGNAGYGTNYTNAGYYTNCCNATGYTNGTNGTNGTN YTNCAYTAYGCNYTNTAYGTNTTYYTNGTNATGACNGCNAAYCCNAGYAARATHMGNTCN ACNGGNYTNCAYCARCCNGTNGGNCCNTGYAAYAARCARGTNAARGTNCARACNCCNYTN GGNCAYGTNYTNCARAARTCNAAYTAYYTNTGYYTNAARAAYTAYTCNGARGAYTAYTTY ACNYTNGAYTGYYTNAARAARCCNCCNGTNGGNAARACNGARTGGTAYACNATHTGY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARAARTAYGTNYTNAARTCNTCNAARATGTCNTGGAARGAYTGGYTNAARGARCAYCAR TTYTAYCARATHGGNTTYYTNTAYATGTTYACNMGNYTNTAYTTYAAYATHAGYCARGTN TAYTTYGGNATHTAYYTNACNAARACNATHGARYTNAARAARATGTTYGTNGCNGTNATG CCNYTNTTYGTNTAYGGNTCNGGNTTYYTNGCNTCNATHYTNGCNCCNACNYTNAAYAAR YTNTCNGGNMGNAARACNTCNTAYTTYGTNGGNYTNGTNTTYGGNYTNATHGCNACNATH TGGYTNTAYTTYATGGAYACNGGNAGYAARCARATGTAYGGNGCNTCNACNTTYYTNGGN ATHGCNAAYTCNGTNYTNYTNATHACNTCNYTNTCNATGACNTCNGAYYTNATHGGNAAR AAYGTNGARAGYGGNGCNTTYGTNTTYGGNGCNATGAGYTTYACNGAYAARYTNTCNAAY GGNATHACNATHYTNYTNATHGARAARTTYGAYCCNTGYCAYGARAAYTGYCCNGCNCAR TCNGGNTAYTAYMGNCAYATHGARTCNATGGTNCCNGGNGGNGCNAAYYTNGCNGCNTTY ATHGTNYTNYTNACNYTNYTNCCNCARACNATHGGNATGMGNMGNAARAARYTNAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AGYMGNTCNMGNTCNGAY TCNMGNTCNAARTCNMGNTCNCARTCNCCNTCN---CCNAARMGNMGNMGNTCNTCNGAY AARAGYMGNMGNTCNMGNTCNMGNTCNMGNGAYMGNMGNCAYMGNMGNGAYAARAARCAY MGNTCNCAYMGNTCNMGNTCNAARGARMGNMGNMGNTCNMGNGAYMGN------CAYMGN CAYAARAARGAYMGNMGNMGNAGYMGNAGYMGNAGYMGNGARMGNMGNGAYMGNMGNTAY AGYMGNMGNAGY---AGYMGNGAYMGNGAYMGNMGNMGN--------------------- ---------MGNAGYMGNAGYMGNGARMGN---MGNGAYAGYMGNAGYCCNAGYCCNCAY GAYGGNAAR------GTNATHAARTTYGGNAAYAARGTNATHAARCCNGGNGCNAGYTTY GGNMGNCCN------TCNTCNAAYTTYTCNAARCCNGTNACNTTYAARGARAARATGMGN CARCARYTNATHAARGCNATHGARGARGGNGCNGAYACNAAYGARGTNYTNGCNAAYAAR GGNGGNTCNACNATHTGYACNCARAGYGCNGGN---GTNCARCARCARGTNATGCCNAAR CCNAARGGNCCNCCNGTNCCNYTNATGGAYACNATHGTNCCNTCNACNGCNAGYYTNGCN GCNYTNACNGTNACNGCNTCNGARGCNGCNATGCARTCNATGYTNGCNYTNCARAARGAR GCNACNGARAARACNGGNATHGARATHCCNAARTAYTAYAAYCCNGCNGCNATHAAYCCN ATGAARTAYGCNGARCARGTNCARAARMGNAARYTNYTNTGGTCNAARGCNAARGAYAAR GAYGTNAAYTCNCARTGGCAYGCNACNAGYYTNTCNGGNGAYGCNGAYGAYAARTCNAAR GARAARTTYMGNAARYTNATGGGNATHAARAAYGAYAGYGGNAAYGCNGCNCCNAARGAR GGNGARAAR---------------GARGARMGNAAYAARCARYTNTTYGAYCARYTNAAY AARGARTAYGARTTYGCNMGNATGGCNACNCAYACNCAYMGNGGNATHGGNYTNGGNTTY AGYTCNTCNGGNTAYCCNCARACNTCNTCNATHATGGCNCCNATHCCNGARGAYAAYCAR GARAARCCNCCN---CCNMGNGAYGAYGARGARYTNAAYGCNTTYTCNAAYGGNAAYGTN GCNTCNATHACNTTYAGYTCNGAYTCNAGYGAYGARAAYGAY---GAYAAYTAYCCNGAY ACNACNGGNTAYATGYTNYTNCCNCARGARCCNGCNGGNTAYGAYGAYGCNGAYGAYGAY ACNGAYTAYGARGARAAYAAYGTNAAYGCNTCNGAYMGNCARTGYGARTCNGARACNATH GAYAAYTGYGGNTCNATHACNGARAAYTGYCAYCCNGAYGGNYTNCCNGAYGARGTNATH CARTCNGARGGNGTNGCNGTNGCNCCNAARGTNACNGCNTCNTCNACNTCNCAYCAYCCN GCNTTYYTNGCNAARTTYCCNGAYGGNAARATHCCNTCNTAYATGCARGTNCCNGAYATH CCNACNAAYMGNAAYGAYGTNYTNTGGAAYAARAARMGNGAYGGNAARAGYTCN---TCN YTNGAYACNGCNGARGAYAARAARATHYTNMGNGCNATGTCNGGNTTYTCNYTNCCNTCN GARAAYGTNCCNGARTGGGCNAARAAYATGTCNGARGAYCARTGGAAYGAYGTNATHYTN CCNMGNTCNGAYAAYTCNGGNCARACNGARCARAARTCNTCNCCNCCNGTNCAYGGNGAR CARAARCARGAYGAYTGGGTNGCNGARTTYCCNGAY------------------------ ------------------------------------------AAYATHMGNCARTTYGGN MGNAGYYTNATGGAYAAYTCNGARGCNGTNTCNGGNYTNYTNAARATHTTYCARMGNTAY GAYATHGTNYTNGTNCARGARGTNMGNGAYTCNACNCAYGCNGCNYTNAARGAYTTYYTN ACNATHYTNGCNACNGGN---GTNGAYTGGCARTAYGTNTCNAGYGCNCCNYTNGGNMGN TCNMGNTAYTAYAARGARCARTAYGTNTAYGTNTAYAARACNGAYTCNGTNAARGTNGTN TCNTCNTAYCARGTNGTNGAYTCN---GCNGAYGTNTAYGARMGNGARCCNTTYGTNGTN GARATHGARTAYAAYTCNGTNTCNTAYGGNAGYACNAARMGNGTNGTNYTNATGGGNYTN CAYGCNAARCCNACNGAYGCNGARGGNGARYTNMGNGARGCNGCNGGNACNGTNMGNAAR GTNTCNGCNYTNATHCCNGAYAAYYTNGGNGTNATHYTNYTNGGNGAYYTNAAYGCNGAY TGYAAYTAYYTNAAYAARGARGAYMGNMGNCAYYTNGAYATHTTY---TCNGGNCCNGAY TTYGTNAGYYTNATHCCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TTYAGYGTNAAYYTNTGYGTNGGNCCNACNTAYGAYCAR GAYTGYGCNYTNCAYTTYAAYCCNMGNGTNGAYGARAAYMGNGTNGTNMGNAAYCAYATG CARGGNGGNAGYTGGGGNAGYGARGARACNGCNGGNGGNTGYCCNTTYAARAARGGNCAY CAYTTYGARATGCAYATGAARGCNCAYCAYCAYGGNTAYCAYATHACNGTNAAYAAYMGN MGNTTYTGYGARTTYAAYAAYMGNYTNCCNMGNGARAGYATHCARTAYATHTAYATHGAR GGNGARGTNYTNATHAGYTAYATHAAYTTYAGYGGNGGNNNNTCNTTYCCNTCNCCN--- ---CCNAAYGTNCCNGGNTTYCCNCCNGCNTTYCCNNNNTAYCCNNNNNNNCCNNNNNNN CCNNNNGCNCCNAGYTAYCCNCCNACNTCNTCNTAYCCNGCNGTNCCNGGNTAYNNNGGN GGNGCNTTYGGNCCNATHTAYAAYCCNCARGTNCCNTTYACNACNCCNATHCARGGNGGN GTNACNCCNGGNAARATHGTNTAYATHTCNGGNGTNCCNCAYCCNAAYCCNAGYMGNTTY ACNYTNAAYATGCARTGYGGNCCNTAYGAYTCNGGNGAYTTYGCNATGCAYTTYGAYGTN MGNTTYAAYTAYGGNAGYGAYMGNAAYCARGTNGTNMGNACNCAYAARCARGGNGGNAAY TAYGGNAGYGARGARAARCARATHACNCAYTTYCCNTTYTAYCCNAAYACNCCNTTYCAR ATGATGATHYTNATHGARCARACNTCNTTYAARATHGCNGTNAAYAAYCARCAYTTYGTN GARTTYTAYCAYMGNATHCAYCCNTTYAAYMGNGCNGAYCAYATHAAYATHAGYGGNGAY GTNMGNYTNACNGARGTNMGNTTYCARACNTCNGGNTTYGTNCCNAAYTTYYTNGTNAGY TCNGGNACNGGNYTNACNCCNACNYTNACNCCNACNACNYTNGCNACNATHGARCARTCN TTYATGGARYTNCARCAYTCNGGNGCNMGNGAYCCNGTNACNCARAGYGGNTTYGTNCCN CCNGTNGTNGARCCNTCNAAYAGYAAYAGYGCNGAYCARTCNCARGAYAGYTAYGAYAAY TCNTCNTCNGAYACNGARTGGGARCCNAGYAGYAARAARYTNTGYATGAARGAYGGNGTN AARGGNGTNGAYTAYATHGTNACNTCNACNGGNACNGTNAAYGTNGCNCCNCARMGNAAR TAYACNMGNMGNAAYAARGAYGARAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNACNGCNTCNGARATHACNACNAAYGARGAYATHAARGGNACNTTYACN TCNAARMGNGGNCARGAYAAYTTYAAYCCNTTYAGYAARGGNTCNYTNTTYAGYAAYTGY ATGGGNATHYTNTGYGGNCCNGTNCCNCCNAGYYTNYTNGAYMGNMGNAARYTNATHGTN CCNGARYTNGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNGARTGYCCNTAYAAYCCNTCNCAY ATGATHTGYCCNYTNMGNATGCCNTAYCAYYTNCAYMGNTGYMGNAARAAYTAYCCNAAY YTNGCNATGTCNGTNTGYCCNTAYAAYGCNGTNCAYGARGTNMGNACNCCNGARYTNAAR TAYCAYATGAGYCARTGYCCNAAYMGNACNYTNYTNGAYMGNGAYATGCCNTAYAAYGCN YTNCAR------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNTTYATGTTYGGNCCNCCNYTNTAYGAYAARGTNAGY TAYYTNTCNGARTCNYTNYTNCARCARGAYCAYYTNACNYTNTGYAARATHTTYGARGAR AAYCCNTCNTTYGGNYTNMGNGAYGTNTCNYTNCARATHATHTCNGARYTNAARAARGGN AARCARGTNATHATHGARGAYGARYTNTAYTCNGCNAAYACNMGNAARAGYATHYTNTCN ACNGTNAARAARAARGTNYTNGGNTGYAARGCNGTNYTNGTNAARATHATHCCNGAYCAY GGNYTNGTNCARGTNYTNTGGACNCAYCARAAYGCNCAYGGNMGNGAYYTNYTNCCNAGY TGYMGNTGYCARAAYGARATGATGMGNGCNAARMGNTGGTTYGAYGCNTCNYTNYTNTCN GTNGAYTAYGGNTCNGGNTTYGTNGAYGCNCCNAAYGARAAYGARGGNTTYGARATHAAR GARGTNCARGCNCCNTTYYTNYTNCARTCNGAYTTYAARTGYGARGTNCCNGCNYTNTTY ATHCARTGGGARGCNGCNGTNTCNGAYGCNGGNGGNATHAAYACNGCNYTNGTNAAYGTN TGYMGNMGNTGGACNGGNYTNAAYCARCAYACNMGNATHATHYTNATH------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARTTYTCNCAR ATHACNCCNTCNTCNTGYATHACNGCNTGYGCNAARYTNTCNATHGARTAYGARACNAAR YTNGARAARCAYATHGAYACNYTNAARGAYCCNAARGTNGARAARACNTTYGAYGAYGTN TAYYTNCCNYTNGARCARATHGCNYTNCCNYTNAAYACNGCNTGGGCNACNGTNAARAAY YTNCAYTAYGTNGCNGCNAGYGAYGAYTAYMGNMGNGCNTTYTCNAARGTNCAYCCNCAR GTNGARMGNGTNAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GGNAARGCNGCNATHMGN MGNAARATHTGGGAYAAYYTNGARGAYAAYAAYYTNGTNTCNGTNCCNMGNCCNTGYCAY TAYMGNATHCCNAAYTTYGARGGNTCNTCNGARGCNGCNGAYMGNYTNACNTCNYTNGAR GARTTYAARAARGCNCARACNATHAARGTNAAYCCNGAYAARGCNCARGARCAYGCNMGN TTYYTNGTNYTNGARGCNGARAARGAYYTNGTNYTNYTNAAYCARAAYCARAARGARYTN ATGGTNCCNACNGARCARYTNAARTCNGGNYTNYTNAAYMGNATHGTNCCNCCNGARGGN GCNAAYAARGARGARYTNMGNCAYTGYTGYACNACNCARGGNGTNAARGARAAYAGYAAR GARATHAGYAGYGGNGAYAARGTNAARYTNGAYYTNATHGTNGTNGGNAGYGTNGCNGTN TCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CCNCARTTYCAYGCNTAY GCNTGYGARCAYATGATHGAYTTYCCNATGMGNGARGAYGAYGTNYTNYTNGTNACNTAY CCNAARACNGGNGTNCAYTGGTCNTGGGARATHYTNMGNATHYTNGTNACNGGNGAYATH GTNAGYAARGGNYTNGAYAARGTNAGYTGYATGATHGARTGGMGNCAY---CCNGAYGAR TTYCARACNYTNCCNTCNCCNMGNATHYTNAAYAAYCAYATGCCNTTYCAYCARCARCCN AGYGAYYTNYTNAARAARAARCCNAARGTNGTNYTNTTYTAYMGNAAYYTNAARGAYGTN GCNGTNTCNTTYTAYCAYCAYCAYTGYGGNATHAARGAYTAYGGNTAYCARAGYGGNGAY TTYGGNGCNTAYYTNGAYMGNGTNGTNGAYGGNYTNGTNGARTCNGGNAAYCCNTTYAAR TTYCAYAARGARTGGGAYGARGCNATHAARAAYCAYCCNGAYYTNCCNGTNTAYTGYTGY GCNTTYGARGAYATGAARGAR--------------------------------------- ------------------------------------------------------------ ------------AAYCCNGTNTCNGARATGMGNAARATHTGYGAYTTYYTNGGNAARTCN TAYGAYGARGAYTTYYTNCARAARGCNGCNAAYACNACNAGYTTYGAYAAYATGAARAAR ACNYTNGGN---------YTNGGNGCNTCNAAYCCNGTNTTYTAYMGNAARGGNCARGTN GGNGAYTGGAARAAYCAYTTYACNGTNGCNCARAAYGARTGGTTYGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYGARGAYGAYCCNYTNMGNGGNYTNCAYMGNATHAGY GAYATGAARCCNTCNAGYCARTGGTAYGGNAGYYTNTCNATGGARCCNGAYGAYYTNACN GTNCAYATHGAYMGNAAYGAYMGNAGYGGNATHAARACNTAYYTNCAYAARGARGGNYTN GTNATHGCNMGNGCNAARACNTTYYTNCAYAARCARMGNMGNACNYTNAARCARMGNCAR TCNGCNYTNAGYGCNGCNAARCARGARYTNAAYAARGAYAGYAGYATHYTNCARCARTCN AAYCCNACNAAYGARGCNACNGARATGYTNGAYAARGTNMGNGAYACNYTNGARTCNGAR ATGGTNCARATHGAYGCNYTNCARTCNAARTTYGAYTCNGAYTCNAARYTNYTNAARGAR AARGARGARAAYTAYCAYMGNYTNGARGGNYTNACNAARGARAAYGARAGYGAYGAYGAR TCNGARTTYAGYCCNTTYGGNMGNCCNTTYCAYGGNGTNAARATHCCNAAYATHGAYYTN AGYGARGAYGARAGYAGYGGNGTNAGYAGYTCNGAYGCNAGYYTNGAYGGNTAYTTYCAY GCNMGNCAYMGNCARTTYTCNAGYACNACNMGNACNGTNYTNGGNTCNAGYACNGGNGGN GAYGAYYTNTCNMGNGCNYTNCAYMGNATHAAYCAYGAYYTNTCNCAYGTNYTNAGYGTN ATHGGNAARGAYGGNGARTCNGTNYTNGGNACNCCNYTNCCNMGNCCNCCNTCNACNCAR CARTAYCARGGNYTNCCNGARGGNGTNCARTGGACNCCNCARCCNCCNAGYCARYTNCCN TCNAARGAYTAYTCNACNATGGTNGCNACNGCNGARCAYTCNYTNGARMGNAARTGGMGN AARTAYTTYGGNGAYMGNMGNCCNCCNTTYACNGCNGTNCCNTCNCAYYTNTCNTCNATH AARGGNTTYGGNTCNTCNTCNAGYYTNTCNMGNGAYACNCAYTTYTCNMGNCCNGGNTAY TCNTCNATHCARTCNMGNYTNGAYGARCARAARGARTGGYTNMGNCARCAYCAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYGTNATGGAYTAYCAYYTNGARACNMGNAAR CCNGTNYTNCARTGYGTNGARGTNTCNTGYAARGARGGNCCNYTNMGNAARACNYTNATG TTYAGYCAYAARATHAGYAARTCNAGYACNATHCARCARGARATHGTNYTNCAYGCNGGN AGYCCNTAYYTNMGNTTYAAYACNTCNGTNTCNTGGCARGARAGYCAYAARATGYTNAAR GTNGARTTYCCNACNTCNATHCAYTCNATGGCNGTNTCNTAYGAYATHCARAGYGGNTTY TTYAAYMGNCCNAAYCAYTTYAAYACNTCNTGGGAYTCNGCNMGNTTYGARGTNTGYGGN CAYAARTGGGCNGAYATHTCNGARCAYGGNTTYGGNGTNGCNATHYTNAAYGAYTGYAAR TAYGGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TCNAGYCARGCNCAYGCNCARATGGCNATGAGYATHAARGCNTCNTTYTCNTAYCARGAR YTNGTNACNGCNACNGAYGGNTTYAGYGAYAARAAYATHYTNGGNGARGGNGGNTTYGGN ATHGTNTAYTAYGGNCAYYTNMGNAAYYTNGAYTGYGCNGTNAARTTYATHAARAARMGN TCNGARGARAAYAARGAYTCNACNGARCARATHCAYAGYGARYTNGCNGCNYTNYTNAAR TGYCARCAYGARAAYATHGTNACNYTNTAYGGNTAYGCNYTNGAYGGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GCNACNYTNGARTTYYTNAARGARACNTAYGGNAAYGCNATHAARGCNACNAARAAY AAYGTNTCNYTNCARMGNGGNAARGGNGTNTCNYTNACNGGNATHATHAGYATHGCNAAR AAYYTNCARMGN------GARAAYGGNAAYGGNYTNAGYYTNGARGAYMGNATGTCNGTN GARCARTGGYTNGAYTTYAGYGCNGARATHACNAGY------------ATHGARAAYGCN GGNGAYMGNGARMGNATHGGNTCNGTNYTNAARGAYYTNAAYAGYTTYATGAARGAYMGN GTNTAYTTYGCNGGNGTNACNATGACNGTNGCNGAYGTNTTYYTNTAYCAYTGYYTNTTY CCNATHTTYGARMGNATGTCNTTYCAYGARAARGARCARYTNATGCAYYTNTCNMGNTGG TTYAAYYTNATHCARAGYGAYAGYAARGCNMGNCARTCNYTNTCNYTNGTNAARTTYYTN MGNACNCARATHTAYTCNAGYATHGGNCAYCAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CCNGAYCARGCNYTNTAYTCNTAYATGATGCARYTNGCNGARYTNMGNYTNTAY AARYTNGTNMGNTGGGCNMGNAAYYTNCCNCARTTYGGNGCNATHTCNACNGAYGAYCAR ATHYTNYTNYTNCARAAYTGYTGGTCNGARYTNATHGGNATGGAYYTNTTYMGNTCNTGG YTNCAYGGNMGNGARAARCCNGARMGNAARACNGTNACNGARAAYGARAAYGGNGGNCAR AAYATGGAYCARAARACN---------------------------TCNMGNYTNGARAAY YTNGTNYTNAARGTNGTNCCNYTNGARCCNGGNGAYTGYYTNGGNTGYAARYTNGTNGGN ACNTCNGTNATGATHGTNAGYGGNTTYATHGTNYTNACNTCNGCNATGGCNGGNMGNAAR MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGGCNYTNTTYAAYACNGGNTCNYTNGTN GARGTNCARCARCCNGCNGGNGAYAARAARCCNCCNACNACNYTNGARGARTTYYTNGAR GCNGARGGNYTNGAYGAYTGGCCNYTNCCNATGAGYYTNGARGGNCCNYTNCAYATHGAR TCNGARGGNYTNTTYATHGGNAAYCARGAYGAYATHGCNGAYATHYTNAAYGARGCNGCN CCNYTNGGNYTNCAYATGYTNGARGCNATGGARGAYAARYTNTCNGTNYTNGARGAYAAR ATHAAYTTYTAYGCNGAYCARATHGTNACNGAYGTNAARMGNCCNTCNMGNYTNGCNGAR MGNYTNTTYCAYTCNCCNACNAARACNTTYATGACNGAYATGTCNGAYTCNGAYGCNYTN AARTCNCAYMGNAGYTCNAARGGNCAYMGNAGYGTNGAYYTNATGGAYACNATGATHGAR ACNMGNAARMGNAGYYTNGAYTAYTAYGCNTTYCCNGGNTTYGTNCAYGGNGARTTYATH GARYTNCCNGCNCARYTNGARGCNCCNCCNATHYTNCAYMGNATHACNAAYGCNCARGAY TTYAAYCCNGGNTTYAARAARTTYTGGAARAARYTNTTYYTNTCNGARGCNTCNTCNGCN GTNYTNCARGAYGCNTTYTGGTGGATHTTYYTNGAYATGTTYAAYAARNNNGARGGNTTY GARGARGAYAARGAYTGYATHTTYGAYMGNATHGCNGAYAGYTAYGTNGCNYTNTTYACN AGYATHAAYACNGAYGTNAARGAYAARTTYYTNTCNGTNTAYCCNAGYTGYYTNTCNCAR GCNYTNTAYTAYACNTAYMGNGARGCNTTYCCNGARTCNAARTGGMGNTTYGAYGARACN TTYAARCARTAYYTNGTNAAYYTNGTNTAYGARTGGGTNATGGGNYTNMGNCCNGTNCCN GGNGTNTGGAARGCNTGGAGYGARGARGGNYTNGARGGNAAYCARACNAGYMGNGARAAY GARACNGCNAARAARATGYTNGARGCNGCNGCNYTNAAYAARAARGTNGARYTNAGYYTN GAYATGGARTCNTTYGCNAARGTNATHGAYAARYTNGGNACNGARCCNGAYGCNACNCCN CAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TAYGAYCCNAAYTAYTTYTCNATG CCNCAYCCNGCNYTNGGNGCNTTYACNATHAGYYTNYTNATHTAYYTNTTYGTNACNACN GTNACNCCNAGYAGYYTNCCNGAYTTYYTNTGGCCNTTYGCNCARATHGGNAARTAYATG TCNAGYCARCAYTTYAAYGTNGTNATHGGNYTNTGYGGNTTYACNYTNATHGTNCAYTGY YTNGARGCNGCNTAYGCNGGNAARGTNTGYCARGAYMGNMGNTAYTCNGTNTCNACNACN ATHAARTGGGTNYTNTCNACNTTYATHTTYGGNTTYCCNTCNATGATHMGNYTNYTNTCN GTNAARCCNMGNTCNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARGAYGARATHGGNAARYTNCARCARGARYTNGARGGNTAYYTNGARTCNYTNTGY MGNATHGARCARMGNGTNYTNMGNAAYGGNAAYGCNGAYTTYYTNCARAAYMGNATGAAR GGNMGNGTNAARAAYAAYTTYYTNGCNGARGARGARGAYYTNGAYMGNGTNMGNYTNMGN GCNGGNGARCAYAAYACNMGNTCNGCNMGNAAYYTNTAYAAYYTNTGYCARAARGTNAAR CARYTNCARMGNGAYGTNAGYCARTCNGAYYTNAGYAARCCNACNAARAARAGYCARATH TCNGCNCARYTNAAYGCNACNTAYMGNGGNGCNGTNMGNGCNYTNCARGTNTTYGTNAAY CARYTNCCNTAYCARGAYYTNCARATGGGNYTNCCNTCNACNTAYAAYGARYTNGCNYTN YTNYTNTGYCARYTNACNACNYTNATGACNYTNACNCARCAYGGNYTNAARGTNGARGGN GARAAYAAYGTNYTNACNYTNYTNGAYCARGTNGAYGAYTTYAAYTCNAARTGGTGYTCN CARTCNAAYMGNGCNGGNCARCCNYTNCAYMGNMGNACNAAYCARAAYATHATHCARAAR GAYTGGGTNAGYGAYACNAARGTNGAYGCNAAYYTNYTNTCNAARAAYGTNACNGARTTY ACNGCN------------MGNMGNCCNGTNTCNAARAARAAYGTNGGNGCNAAYMGNCCN ATHCCNMGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATHATHGAYAGYAARYTNTTYGARTGYCCNCAYCAYGARMGNYTNCARTCNGTN ACNCCNACNYTNYTNTCNAAYGCNGCNMGNYTNTGYGCNTCNACNGARTAYYTNTAYCAR ACNYTNTCNCAYYTNGCNTCNMGNYTNAARYTNAGYGTNACNAARACNYTNAAYGTNATH GGNGARGAYGGNTAYTCNGCNYTNCAYYTNTCNGTNATGAAYGGNGAYYTNAARGCNACN AARTAYYTNYTNGARGTNGGNTCNGAYTGYAAYAARAARTCNGARAGYGGNAAYTCNGCN ATHTCNYTNGCNGTNGCNTAYAGYCAYGAYTGYYTNGTNCCNYTNYTNYTNAARMGNTCN GAYGTNAAYACNCARGAYYTNGAYCAYGAYACNCCNYTNATGTTYTCNGCNTGGAAYAAY GCNCCNACNATHACNTCNGCNYTNATHCARCAYGGNGCNGAYGTNAAYMGNAARAAYAAR TAYGGNAGYACNGCNATHTGGAAYGCNGTNTAYCARTCNTCNGCNCARTGYGTNYTNATH YTNYTNACNAAYAAYTCNACNATGGAYGTNCCNTGYGARGGNACNGAYYTNTTYTTYAAY GARNNNGAYTGY---------MGNGARAARATHACNAARYTNTAYCCNGGNTAYAARMGN TCNYTNYTNTGGGTNGCNGTNGAYMGNATHGGNTTYAGYGAR---GGNYTNAARGTNYTN YTNATHYTNYTNGARGCNGGNTAYGAYGTNACNAARGARCAYTGGYTNMGN---AAYTTY MGNYTNCCNTCNGCNGAYTTYCCNAAYAAYYTNCAYAAYAAYCCNGCNYTNYTNGAYATG YTNCARTTYCARTAYAARMGNCCNCARAAYYTNAARGAYYTNTGYMGNAAYTCNTTYMGN AARMGNCARAGYAAR------YTNCCNTTYCAYAARTGYYTNMGNAGYYTNGGNYTNACN CARACNYTNAARGAYTTYYTNACNYTNTCNTAYGTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARMGNGARMGNACNMGNGAYTTYGAYMGNMGNMGNCCN GCNGARGGNTGYTCNGGNAARGTNATGGAYATHTTYTTYYTNYTNGAYTCNTCNTCNTCN ATHTAYATHAAYGAYTAYATGTCNCARCAYMGNYTNGTNMGNGAYATHATHAGYMGNTTY GAYGTNAGYAGYGARTCNACNMGNGTNGGNATGYTNACNTTYAGYGAYGAYYTNGARMGN CCNGTNATHTCNYTNAAYCARTAYAGYGGNAARGCNGARYTNYTNTCNAGYATHTCNGTN CARAAYYTNCCNTAYMGNACNGGNGTNACNAAYACNGAYATGGCNATHMGNTAYGTNMGN CARYTNAAYAAYTTYMGNCARGAYATHACNAARGTNATGGTNGTNATGACNGAYGGNGGN TCNMGNTCNCCNGGNTCNACNGCNMGNGARGCNGARYTNGCNMGNAAYGCNGGNTTYTAY ATGTTYGTNGTNGGNATHGGNCARTAYATHGARGARMGNGARTGGMGNTCNATHGCNAGY GAYCCNGAYGAYAGYTTYGTNTAYAAYATHACNTCNCCNMGNTTYYTNGAYGAYGTNCAR TTYTCNYTNCCNCCNMGNGCNTGYGAYYTNCCNCCNATHATHYTNGGNGGNTCNTGYGAY GTNTCNMGNATGTCNGARGTNTAYTTYGTNGCNGGNMGNACNGCNCARGAYTCNGTNCAR AAYTTYYTNGAYAAYTTYGGNMGNMGNACNMGNGAYCARMGNGAYYTNYTNMGNGTNAAY TTYYTNATHGAYGGNTGYGTNCCNGTNCARGAYATHCARYTNYTNAAYGARGAYCCNTTY ATHTGYGARMGNTAYGAYMGNCARGGNAAYGCNGTNYTNTCNMGNGGNGCNGCNGARATG TTYGCNGARGCNGTNMGNGCNYTNMGNGARAGYMGNGAYTCNGARACNAAYCAYGTNATH GTNYTNTTYGCNGAYGARGARACNATGAGYACNGAYMGNTTYGAYYTNGCNAAYAAYGCN MGNAAYGCNCARAAYTTYGARGGNGCNTCNGTNGTNGTNGCNGAYYTNGGNATHMGNACN TAYMGNGAYTTYGCNCARMGNATGGCNTCNGGNMGNAAYAAYTTYATHAGYTTYGCNAGY GGNAGYTTYGCNGGNCARTCNAAYGCNCARMGNAAYYTNYTNGAYTCNATHTGY------ ATGGCNGAYAGYACNAAYCAYCCNGAYYTNYTNTTYGAYAGYCARCCNGARAGYTCNGGN TTYACNAAYGAYGAYTTYGARAARGTNGAYGCNCCNGGNGGNGGNTTYGGNCAYGAYGAY GTNACNGCNGCNGCNGCNGCNGCNTAYGARTAYGAYGTNAAYCARGAYGCNGARATHTCN ACNACNGCNGAYGCNGAYTTYGARGGNGARGARGARGCNGARGCNGAYMGNTTYGCNGTN ---------------------------------------------------TCNMGNGAY GAYGARCCNGCNTAYCCNTCNTGGGGNGAYGARGTNGARGAYAAYGAYGAYYTNACNGCN CARGTNCARCCNTCNGCNCCNGTN------CCNGARAAYAAYGAYCCNYTNGTNAAYTTY GAYGAYAGYTCN---TCNGGNCAYGAY---TAYTTYATGCCNTCNGTNCCNTCNAGYGAR ACNCCNAGYAAYYTNYTNCARACN---CARYTNGAYGARATHATHGARCCNAARMGNGAR GARAGY------------------------------GARAGYGTNAARGARAGYAARCAR GAYTCNGAYCCNACNCCNGTNGCN------TCNGCNAARGGNTCNTGGYTNAARGGNGTN GAYCCNMGN---------------------------------GTNATHGAYYTNATHTAY TGGMGNGAYGTNAARACNACNGGNATGGTNTTYGGNGCNATGTTYGTNGTNYTNYTNTCN YTNGCNATHTTYTCNYTNATGAGYGTNYTNGCNTAYYTNTCNYTNGCNGTNYTNGTNGTN ACNTTYAGYTTYACNGTNTAYAARAARATHATGGGNGCNGTNCARAARTCNAAYGARGGN CAYCCNTTYAARCARYTNATHGAYATGGAYATHACNYTNAGYGARGAYAARYTNAARAGY GTNATHCARAGYATHYTNAARAAYGTNAAYTGYACNATHAGYGARYTNMGNMGNYTNTTY YTNATHGARGAYATGGTNGAYTCNATHAARTTYGGNYTNYTNYTNTGGGTNYTNACNTAY GTNGGNGCNTGGTTYAAYGGNATGACNYTNATHATHYTNGTNGTNATHAGYATHTTYACN YTNCCNAARGTNTAYGARACNTAYAARGTNCARATHGAYAAYTAYATHGCNATGGCNAAR GCNCAYGTNGAYAAYGCNATGACNATHGTNCARAGYAARYTNCCNTTYYTNAARAARAAR GARAARGCNCAR------------------------------------------------ ---MGNGGNGARCARGTNCARATHATHTCNGARCCNMGNCARTTYTAYGARATHYTNAAR GTNAARACNMGNAARGCNAARMGNMGNGTNACNYTNGCNTCNYTNTAYYTNGGNAAYGGN MGNYTNGARCARGAYYTNGTNTCNTGYATHGAYGARGCNTGYCARACNGCNYTNTCNAGY GGNTCNYTNGAYYTNGARGTNAAYGTNYTNYTNGAYTAYACNMGNGGNTCNMGNGGNAAR GTNAAYTCNMGNACNATGYTNTGYCCNYTNATGGARAARTGGCCNAAYGTNAAYGTNGCN YTNTAYCAYACNCCNGAYYTNMGNGGNTGGYTNAARAARGTNGTNCCNGARMGNTTYAAY GARACNATHGGNYTNACNCAYATGAARGTNTAYYTNGTNGAYGAYAGYTTYATHATHAGY GGNGCNAAYYTNAGYAAYGAYTAYTTYACNAAYMGNCARGAYMGNAAYATHYTNTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ACNGAYTCNAAYTAYGTNMGNAARAAYYTNACNGAYAGYGGNCAY GCNATGYTNYTNTCNGCNTTYCARMGNGAYAAYGCNMGNAGYTCNCCNCARACNATHTCN ACNGCNCARTCNTCNCARGTNAGYGGNGGNTCNGTNACNGCNGAYMGNYTNATHAAYGCN ATHATHATHCAYTCNATHAAYCARACNTCNCCNGARGARAARAAYAAYGCNTCNCCNTCN CCNYTNMGNYTNGCNGGNACNCCNACNTCNGAYCARGCNTCNAGYTCNACNAGYGAYCAR MGNCAYATGATHGARTCNAARMGNTAYATGATGCCNGAYGGNGGNGGNMGNCCNGAYATG ATGGAYCCNATGCARMGNGARATGATGGAYCARMGNAARMGNCARATHGCNGCNGARCAR MGNCARYTNCARGARATGCAYGGNMGNMGNCARCAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNAAYCCNAAYCARACNAARGCNGARATHATHYTNCAR ATHGAYTTYAARGGNMGNYTNCCNMGNAARYTNGTNGARAARAGYGTNCCNAGYTCNATG GTNACNTCNTTYAGYCAYTAYATGGARTAYATGAARAARAAYGGNYTNYTNATGTGGMGN TCNCARACNYTNAARMGNGGNMGNCARATHYTNGCNYTNACNCARMGNCAYYTNGCNGCN GARGCNGGN---GGNGCNACNCCNACNCCN---CCNMGNCCNAARCCNAARTCNMGNGGN TTYGGNYTNYTNAARTTYYTNGGNYTNGGNYTNCCNYTNGCNACNGGNGGNGTNGTNGGN TAYGCNTGGTAYGAYAAYGAYTTYMGNAARCARYTNGARGAYAAYGTNCCNTAYGCNAAR GARATGYTNGARAAYGTNYTNGTNCARGAYGAYATGAAR---ACNCARMGNGGNCCNAAR TCNCARGTNCCNGTNCCNATHTTYGAYTCNAARGAYGTNYTN------------------ AARAAYGARTCNTCNAARGTNGARTCNMGNAARGCN------------CCNGGNYTNGCN YTNGARGARAARTCNGARACNGARGCNAARAARGARGTNYTNTCNYTNGARCARCARYTN MGNAAYAARGARATGGARGAYAARGCNGAYAAYGCNGCNYTNGARGTNGTNATHGAYAAR YTNYTNGARTCNGGNCARAAYTGGGTNTCNGARGCNGCNAARGCNCARYTNGAYGTNGCN AARGCNACNAARAAYCAYAGYACNYTNYTNAARAARGCNATGGAYGARACNTCNAAYATH CARGAYAARGAYTGYGARTGGGARGCNGTNACNGTNGCNTAYAARGARMGNGARATHTCN GTNTCNMGNGCNAAYGARYTNGTNGAYGARGCNMGNMGNAGYATHGARAARYTNAARAAR GTNYTNGAYGARGCNAARGCNAAYAARGTNACNATGAARAAYCCNTCNATHTAYCCNGCN ACNAARAARYTNGCNGAYTTYGCNAAYGARATGTCNAAYGCNGGNGCNCARGTNMGNCAR GCNGAYGCNGAYGCNAARGTNATGYTNAARTAYAARGAYYTNGTNGAYAARGGNMGNAAR CARTTYCARYTNGARYTNGARAGYYTNACNCCNGAYGCNAARGTNGGNGGNAARAGYMGN AARYTNACNGARGARGARYTNAAYGCNYTNATHGCNCAYGCNCAYMGNMGNATHGARCAR YTNCARMGNCARATHGCNGARCAYYTNGCNATGGARMGNAARMGNYTNACNYTNGCNYTN GARGCNCARAARGARGARAAYAARGGNATHACNAARTCNGCNGTNATGGAYGARMGNTCN MGNYTNTAYGCNGARTTYGARYTNGARAARCARAARATGGARATHGARTTYGCNGCNTGG ATGGARGCNGAYGTNMGNAARCARYTNAGYMGNCARTCNGCNGCNCAYAGYGAYCAYYTN AARGAYGTNYTNACNGTNCARGARGCNGARYTNAAYAAYGARTTYCARMGNAARATGAAY ATGAARYTNYTNGARGARMGNGARAARTTYCARTCNGARACNGCNAGYTGGATHTCNMGN YTNAARGGNATHGARGCNGCNGTNGAYGCNMGNGCNGCNAGYGARAARYTNGCNCAYACN GCNCARGAYYTNTGGYTNGCNTGYATHGCNYTNAAYTCNACNATHCARTTYGGNAAYGAR ---GTNGARGAYACNCCNATHCCNYTNCARCARCARGTNGARACNATGYTNACNTCNTCN AAYAARCAYCCNTTYGTNGARACNGTNGCNAAYACNATHCCNCARGTNGCNYTNGAYMGN GGNATHTAYACNGARAAYAGYYTNMGNGAYMGNTTYGTNAARGTNTCNCARGTNAGYMGN MGNYTNGGNYTNATHCARGARTCNAAYGCNTCNYTNTAYCARTAYYTNGTNTCNTTYYTN CAYTCNTTYTTYACNGTNAGYAGYGTNGCNGCNTAYTCNGARAARGAYYTNGTNTCNYTN GGNGARATGGAYAAYTTYAARYTNGTNGCNAAYGCNCARTAYTGGATGGARAARGGNAAY YTNGAYYTNGCNGTNMGNTTYATGAGYCARYTNACNGGNGARTCNMGNMGNGCNGCNAGY GAYTGGATHACNGARGCNMGNYTNYTNYTNGARACNMGNCARGCNGCNCARACNATHYTN ACNTTYGCNTCNGCNACNGGNYTNGCNTCNACNTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNATHCARGAYGTNTCNYTNCCN TCNTCNGAYATHGARCCNGTNCCNGARYTNGGNGCNGTNACNYTNACN---------AAY TCNAGYATGCCNCCNCARCCNTGYATG------ATGAAYACNTCNYTNGARTGGGAYACN GGNAAYATGACNATHTTYGGNAAYYTNACNGCNYTNCCNGARGAYAAYATHGAYGAYATH GAYYTNGARAAYATGGARGAYYTNTTYAAYACNATG------------ACNGARGCNTCN GAYYTNATHAGYAAYGTNACNCCNCAYACNGAYGTNAGYAAYYTNGTNYTNTCNGGN--- ------------------------------AAYGAYACNATHAAYACNYTNCCNTCNACN TCNTTYTCNGARGAYYTNGCNGAYGCNTTYGAYGGNYTNGARGGNGCNACNGGNGGNGCN AAYTAYAGYAGY---CCNGAYGGNTAYGAYGTNCCNCARAARAARATHTCNMGNYTNTCN GARTCNTCNTCNGAYTCNGGNTTYGGNGGNAARGGNGCNTTYAGYTCNTCNTCNTCN--- ---TCNGCNTCNTCNTCNTAYGTNGGNAGYCCNGCNGAYTCNACNATGGGNTAYAAYTCN ACNAAYTCNAAYGAYACNGAYAAYGAYCCNCAYGGNACNAARGCNGTNGCNCAYCARGTN GCNCAYAAYCAYACNTAYAAYACNYTNCCNGGNCAYGTNCCNMGNGARGTNAARAARTAY GCNCCNAARCARCAYTCNAARAARGGNCCNCARTGYAARGAYGARAARAARGCNAAYGAR ATGAARATHCCNTTYAGYGTNGAYGARATHGTNGARTCNCCNGTNGARACNTTYAAYGAY YTNYTNACNAARTAYAGYYTNAGYGARGAYCARYTNACNYTNATHMGNGAYATHMGNMGN MGNGGNAARAAYAARYTNGCNGCNCARAAYTGYMGNAARMGNAARGTNGGNGTNATHGTN ACNYTNTCNGAYGARATGGTNGAYYTNCARAARGCNMGNGAYMGNYTNGTNGARGARMGN GCNGARATGGARMGNGARACNMGNMGNATGMGNGARAARTTYGGNCAYYTNTAYACNCAY ATHTTYCARTCNYTNMGNGAYGARCAYGGNCARCCNTAYGAYCCNAAYYTNTAYTCNYTN CARCARTCNAGYGAYGGNAAYGTNTTYYTNGTNCCNMGNAAYGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ACNAAYGTNTGYAAYATHGTNATGTTYTGYAARATHGGNTTYAARGAY ACNTTYAAYATHTCNYTNATGGCNYTNTCNGTNTCNGAYYTNGGNAGYTCNATHATHYTN TTYTGGATGGGNAAYCCNYTNTTYATHTTYTCNGAYGTNCCNTTYGAYACNYTNTCNYTN GTNTAYYTNACNGGNGGNTGGGTNMGNATHTAYTTYACNMGNACNACNAGYTGGYTNACN GCNATGATHTCNYTNGARMGNTGYYTNTGYATHATHATHCCNYTNAARGTNAARTCNATH YTNACNMGNAARMGNTCNATHTAYACNATHATHACNATHTTYTTYACNATGTCNTTYACN ATGCCNAARACNYTNYTNGGNYTNACNTTYTCNGAYGAYMGNCCNACNGTNTAYAAYGCN ATHATGAGYGCNAAYYTNATHYTNGCNTTYATGTCNTTYTTYATHGTNATHYTNAGYACN TCNYTNYTNGTNTCNAARYTNAAYCARAARACNAARTGGMGNGGNGCNAGYGTNAARGGN CARGARTCNYTNGARACNATGACNTCNMGNGAYCARMGNGTNAGYAARATGGTNATHYTN ATHTCNTCNGTNTTYATGGGNTGYYTNACNCCNGGNGTNATHYTNTCNATHGTNATGYTN TTYGTNCCNCARTTYAGYAARGGNMGNGGNTAYCAYAAYYTNTTYACNATGGTNTGGGCN ATHAAYCAYATHACNGARGCNATHAAYTCNTCNGTNAAYATHTTYATHTAYTAYAAYATG AGYAAYMGNTTYMGNAGYACNATHMGNGGNATGTTYATGTTYAAYAARGTNACNACNYTN GCNMGNTTYGTNCCNMGNGTNMGNAAYGCNMGNTGYATG------GGNCAYGGNGTNCCN GCNCAYTTYAARCCNYTNMGNCARGTNTGYCAYGARAAYAARGCNACNATGGAYTTYATG CCNGTNCCNTCNGGNTCNTGGCARAARGCNTAYGCNGTNACNAAYTCNMGNAAYAAYATG YTNYTNATGGGNAGYYTNGGNGCNACNATHGTNACNTTYACNATHYTNTAYCARACNGGN TGYATHTAYYTNCAYGGNCCNCCNCCNGCNTAYAAY---------------------ATH AARGTNCCNCARMGNYTNCAYAARYTNGTNAAYGARAAYMGNACNYTNYTNGARAARTGY TCNACNGCNAARYTNGTNAARMGNATGCCNAAYACNGAYGTNGCNCAYAAYTTYGTNGAR MGNYTNAAYAARTCN---TAYGARGTNAGYCARGARYTNTGGACNMGNGTNAARGCNYTN ACNTGYGTNCARAGYCAYCAYYTNATGYTNGAYTCNYTNMGNTCNYTNGGNATHGARGGN ATGTCNGARGARATHTCNTTYCARACNGTNTAYMGNACNAARMGNYTNYTNGARTTYATH YTNACNAARTTYGCNCARACNCARGAYGARGCNGAYTAYTTYTCNAARGTNCARTTYMGN CCNMGNCARTCNAGYGGNATGACNYTNACNTCNGAYTCNGAYGARAARGAYGTNATHAAR ACNTTYTTYAARAGYCARGARACNGARATHATGCARATGAAYAAYCARTTYGTNATGGGN ---GCNYTNGCNAGYTCNAARACNTGGACNCAYYTNCARTTYGARAARAAYYTNTAYAAR YTNYTNYTNCAYYTNYTNTGYYTNTCNGARTCNCARTGGTGGAARGTNYTNTGYGARGAY TCNACNAAYGGNAGYACNGTNCARATGATHCAYAGYYTNYTNACNTCNAGYGGNGARTTY TTYCCNGCNATHGTNGARAAYCCNTAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGMGNTAYGARGARMGNCCNGGNGTNMGNGCNGARGCNTGYCAYTCNYTN ACNGCNYTNGAYATHGAYGAYGARGAYGTNATHGARATHYTNCARGAYMGNYTNYTNGTN GARTCNAAYCARYTNGTNMGNGARGARATGATHGARGCNYTNTCNYTNTTYGGNTAYAGY ACNTCNGARGAYATGGAYACNGTNGCNCARATHAARGCNGARGTNMGNAARYTNTGYACN MGNAAYATHATHGCNTCNCARATHATHGTNAAYGARAAYGAYGARACNAARMGNGARCAR YTNMGNMGNAARGTNTGYCARACNGARAARGAYATHGARACNYTNAAYGARMGNAARGAR ATHATHYTNMGNMGNATHMGNTCNCARGCNMGNAGYAGYMGNGCNAGYAAYAARGAYAGY YTNAGYTCNTCNCCNCCNCCNMGNACNTCNACNCCNYTNYTNCCNACNGTN------AAR CAYAGYAGYACNACNACNCCNGARCCNGTNAGYMGNGARGGNACNGTNTTYACNCCNACN GCNGAYAARGARYTNGARGCNATHYTNAAYCAR---GAYGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHGARYTNYTNGAYCAYMGNGCNACNGTNMGNTGYYTNGAYTTYACN AARGAYGGNYTNCARYTNYTNTCNGCNTCNCAYGAYAAYACNYTNAARYTNTGGGAYYTN GARAAYGAYGGNAAYATGTAYCAYACNTTYAARGTNCAYGGNAARTGYTTYGGNTGYMGN TTYTCNCCNAAYGGNAARTGGATHGTNGCNAARMGNACNGTNYTNCARTGGMGNACNTCN ATHAARGAYAGYCCNGTNMGNYTNAGYGGNCAYCAYAAYGAYGTNGTNTCNTGYGAYTTY AGYCCNGAYTCNGCNATHYTNGCNACNGCNGCNTTYGAYACNAARATHATHYTNTGGAAY ACNGAYACNCAYGARCARYTNAARGTNYTNGGNCAYYTNCAYCCNAGYCCNAGYYTNATH TAYGCNGGNGGNGCNAAYGAYCAYTAYGTNMGNAGYGTNGCNTTYTCNCCNAAYACNYTN ATHGTNGGNTCNATHTGYGAYGAYAGYTAYGTNMGNTTYTGGAAYYTNAGYGARGAYMGN GAYCCNGTNTCNATHTCNTCNATHGGNGAYGCNATHTCNTGYGCNTTYTCNACNGGNGGN GGNGTNYTNGCNATHGGNTGYMGNAAYGGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARACNATGCCNACNAAYCARYTNTCNGARTCN ATGYTNATGGAYATHACNYTNCARAGYMGNGAYGGNMGNCAYTCNCARGARGAYAARMGN GAYGTNCCNCCNYTNGCNATHTCNATGGAYACNGAYCAYTTYAARTGGYTNCARGARCAR GCNTCNAARGCNCARGTNMGNGCNMGNCAYAGYTCNAARATH---AARCCNGAYYTNMGN CCNGAYGTNACNATGGARGGNATGGARGARGGNGAYGARGARAGYAGYCAYTCNATHMGN YTNGARACNYTNAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNYTNGAYATGATGGTN------------------------ ---------------------------------AARGCNYTNGAYYTNGAYTGYCARAAR GTNGARYTNACNGTNYTNACNTCNAAYAARAARGCNAARGCNTTYTAYGARAGYATGGGN GCNATHGAYCARACNGARGCNGAYGGNMGNCAYAARATGMGNYTNACNMGNAARCARATG GAYYTNTTYGTNAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG TCNAAYATHATGTAYTGGGGNGARATHCCNGARGTNTCNGAYACNGAYTCNGGNATHGCN GCNYTNGARMGNGARCARATHACNMGNCCNAARCCNATGGAYGTNGARGGNCAYYTNYTN CAYCARCCNTCNAAYMGNCAYCAYCCNCCNACNAAYGARATHYTNGCNACNGAYCAYTTY AARATGGAYCCNGTNGTNYTNCAYACNATHMGNYTNYTNCARCAYATHAARAARGTNMGN GCNGCNATHGARTCNYTNCARCAYGAYATHAARTCNGARTCNGARCCNACNAGYATHAAY GTNGGNCCNATHCCNGARTAYGAYGGNCCNCARATHAARGAYMGNTCNCAYCARAARTAY TTYACNGARGARGARTAYGARAGYGAYTTYGTNAARGGNGTNCCNAARCCNCARCCNCAR ATHGAYGARGCNACNTGYMGNAARYTNYTNMGNMGNTCNACNGCNGCNATHTGYGCNCAY YTNTCNATHGAYACNGCNCCNGARTCNGTNYTNGAYACNYTNACNGAYATHTGYCARGAR TTYTTYTCNCARTTYACNMGNCAYYTNGGNGTNGCNACNGAYMGNMGNGCNTCNCAYGGN AAYAAYGGNTTYCCNGAYTCNATHGARMGNGTNYTNCAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARGTNAGYTTYGCNGGNATHTCNACNTCN ACNACNMGNTCNAARCCNTGYATHCAYYTNTCNAARACNGAYGCNYTNYTNAAYGARAAR GTNTGYGTNYTNGTNAAYGGNYTNCARGCNGAYCARAARGTNACNYTNCARACNTAYGTN GAYGARGGNAGYAARAGYTAYGGNTCNTGYGGNCAYTAYGTNGCNGAYAGYGARGGNMGN GTNAAYACNTTYGARCAYGARTGYYTNGGNGGNACNTAYGAYGGNACNGARCCNATGGGN YTNTTYTGGAGYATGCARTCNYTNCCNGGNGGNMGNCCNMGNMGNATHYTNAAYYTNGAY GTNACNAARCCNGTNGAYGTNCARATHTCNYTNCAYACNGAYCAYGTNGAYTTYGAYGAY YTNCCNTGGAGYCCNGAYGCNCCN---YTNGCNTCNTGYCAYTTYTCNCARMGNTTYATH GAYGARGGNGTNAARGTNATHCCNGTNAARGARGAYGGNGTNGTNGGNACNYTNTAYYTN CCNGARGGNCCNGGNCCNTTYCCNGCNGTNATHGAYGTNTTYGGNATGACNCCNGTNACN CCNGGNCAYMGNTCNTCNYTNYTNGCNTCNGGNGGNATHGCNTCNYTNAAYYTNACNTAY YTNGGNCARCARGGNYTNGCNTCNTCNTCNTCNGAYATHGAYTTYACNTAYTTYYTNAAR GCNTTYGAYTGGYTNTCNMGNCAYCCNAGYATHAAYCCNAAYGCNYTNGGNGGNATHGGN AGYTGYATHGGNGCNGCNTAYGTNTCNYTNATHGTNTGGAARMGNCCNAAYYTNMGNTGY TAYGTNAGYATHAAYAGYCAYACNMGNCCNGARGGNCCNAGYCARATGGTNGARGGNGAR ATGGTNAARACNGGNTCNTGGMGNTGGGAYMGNATHGARGARGTNGARGGNGCNCARGCN TGGMGNCCNATGGCNMGNGTNGARGAYAARGTNCCNTCNYTNCCNTAYTGGMGNCAYGGN GCNAARGTNYTNCARATHCARTGYGARGAYGAYCAYTGYGTNAAYCCNGAYTGYYTNMGN GCNAGYCAYGARGTNGTNCCNCARGARYTNMGNGCNAAYATGGARTTYATHAGYTAYCCN GGNGCNGGNCAYATHYTNGARCCNCCNTAYYTNCCNYTNTGYMGNATGAAYTAYAAYAAY ATHTTYCARTGYATGYTNTTYTGGGGNGGNAARCCNAARCCNCAYGCNCAYGCNCARGAR GAYAGYTGGCCNMGNATHGTNGAYTTYYTNCARMGNAAYYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CCNATGTTYGAYTCNCCNATHGCNAAYGTNACNATHAARGARATGAGY ACNGCNGTNYTNCCNTGYTCNGTNAARTAYYTNGGNAARMGNCARGTNATHTGGACNGAY AARTAYTCNACNGTNYTNACNTTYGARGARMGNMGNGTNATHGAYGAYAAYMGNYTNAGY GTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYGARYTNCARAARCARYTN GGNGGNTAYGGNMGNTAYCARGTNATHATHTAYATHYTNATGGGNATHGTNTAYATGMGN GGNTGYTGGCAYGCNTTYGTNCCNATHTTYCARGGNTAYGARCCNGGNTAYCAYTGYMGN CCNGCNCCNGGNGTNCCNYTNAAYGARTCNGTNCCNGGNCAYAAYGAYAGYGGNGGNTTY GARTAYGAYCARTGYACNCARTAYGTNAAYTTYTCNYTNGGNAAYCARACNGARGAYTGY ACNMGNGGNTGGGTNTAYTAYTTY---GAYAGYCAYATHTCNTCNATHGTNTCNGARTTY ACNYTNACNTGYGAYMGNTCNTAYYTNAAYAAYYTNGCNACNACNYTNTAYATGGTNGGN GCNACNTGYGGNGTNATHTTYYTNGCNCCNGTNTCNGARMGNGTNGGNGGNAARCCNGTN ATGYTNGTNTGYYTNTGGYTNCARGCNGTNATHGGNACNGTNYTNCCNTGGGCNGGNAGY ATHGTNTTYTAYYTNGTNYTNAARTTYTTYATHGGNGTNTTYAAYATGACNATHGCNYTN TGYGTNGCNGTNYTNATGCAYGARACNTTYGAYTCNACNCAYMGNGARATHCCNTCNATH GGNGTNCARTTYTTYTGGGCNTTYGGNATHATGAGYYTNGCNYTNTTYGGNTAYYTNYTN CCNGAYTGGAARCAYYTNCARYTNGTNATHACNYTNCCNGTNCCNATHYTNAGYATHGCN TTYATHTGGYTNATHCCNCARTCNYTNCCNTGGYTNYTNTCNAARGGNAARYTNAARGAR GCNGCNMGNGTNATHAAYMGNTTYATHAGYATHAAYAAYYTNCCNGCNATHCCNAAYYTN GAYAAYGTNYTNYTNAGYTTYAARAARAAYTCNGTNAARGAYTCNAAYATHTCNGAYTCN AGYYTNAAYAGYCAYGGNGAYGAYCAYGTNTCNTCNAAYCARGGNTAYGAYGARGGNGAY TCNAARGTNTAYACNGTNYTNGAYATHTTYAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNTAYCCN AARGCNGGNACNCAYTGGGTNTGGGARATHGTNMGNTGYYTNCARGCNGGNACNGTNGCN GTNCCNGTNATHGARAARGAYAAYTAYATGYTNGARTGYAARGGNAARGAYTAYATHGAY TAYYTNCCNTCNCCNMGNACNYTNAAYACNCAYYTNMGNTAYAGYCARYTNCCNGARGAR GTNNNNTCNAARAARTGYAARYTNGTNTTYATHAAYMGNAAYCCNAARGAYYTNACNGTN TCNATGCAYCCNTAYTAYTAYGTNCARTAYGTNCCNATHCCNYTNAARCARGAYYTNGAR ATGAARGTNAAYTGGGCNGCNTCNCCNAGYACNGCNCCNAARCARGAYACNAGYAARCAY TTYCAYGTNTTYGTNGGNGAYYTNAGYTCNGAYATHGARCARCAYCARYTNMGNGAYGCN TTYTCNATGTAYGGNGARATHTCNGAYTGYAARATHATHMGNGAYCCNGCNACNATGAAR TCNAARGGNTAYGGNTTYGTNTCNTTYGTNAAYAARTCNGARGCNGARACNGCNATHAGY GGNATGAAYAAYCARTGGYTNGGNACNMGNCCNATHMGNACNAAYTGGGCNACNMGNAAR CCNYTNGCNCCNGTNGTNAARGARAAYGCNAARCCNYTNYTNTAYGARGARGTNTTYGGN CARTCNAGYCCNACNAAYTGYACNGTNTAYTGYGGNGGNGTNACNAAYGGNYTNACNGAR GARYTNATGMGNAARACNTTYTCNCARTAYGGNACNATHCARGARGTNMGNGTNTTYAAR GAYAARGGNTAYGCNTTYATHMGNTTYAGYACNAARGARGCNGCNACNCARGCNATHTGY GCNGTNCAYGGNACNACNATHAAYGAYCARCCNGTNAARTGYTCNTGGGGNAARGARTCN AAYGARTCNAGYCARACNAAYCARCARTCNAAYAGYCCNCCNGTNGTNATGGTNCCNTCN CARCARCARCARCCNATHGCNGCNACNCCNGCNGCNGCNCCNTAYGGN---CARTTYTAY AAYATGAAYTAYTAYCAYGGNGCNCCNTAYGCNGCNGGNACNCCNACNTAYCARAGYGCN GTNCCNGCNCARGGNCARTTYATHCCNACNGCN---GGNCARTGGCCNGGNGGNTAYTCN AAYTAYCARGCNTAYGGNAGYATGAAYGTNCCNGTNGGNGGNTAYGCNGGNYTNCARATG CARCCNGGNGCNCARCARCARCARTTYAGYGGNCARGGNCARGGNATGGTNGGNTAYCCN ATGCARCAR---ATGGCNMGNTCNAAYGTNMGNTAYGARGTNYTNCCNTCNGARGARCAR AAYGTNGCNGCNGARCCNGTNGARGTNGCNATGGTNGTNCCNCCNCCNAGYTAYACNGAR AAYGCNGTNATGGARCARGAYGGNGAYAAYCCNGCNTTYGGNCCNGCNAARYTNCCNAAY TAYGTNGAYGCNACNACNYTNCCNACNTAYGARGARGCNGARMGNAGYAARGCNGARGAR ------TCNGCNTCNGCNAGYAAYCAYGAYTGYGARACNGGNMGNATGGCNTCNATHAAY GGNGTNAAYGARGCNACNATHGGNACNGAYGGNATGTTYATHTGYACNTTYTTYATHTCN TTYYTNTTYAAYTGGYTNGGNTTYYTNYTNTCNYTNTGYYTNTCNAAYACNATHGCNGGN MGNTGYGGNGCNYTNTCNGGNYTNGGNYTNTCNATHGTNAARTGGGTNGTNATHGCNAAR MGNAAYAAYTGGGGNACNGAYTTYGCNGAYGGNGAYTCNTGGYTNAAYYTNACNCARYTN CCNAAYCCNCCNGTNYTNGAYGARGARGGNAARAARAARYTNGCNAARAARGCNGARATG TTYGAYATHGAYGTNTCNGGNAARAARATGTCNATHTAYGTNCARCARGTNATHAAYAAY GARYTNCARACNYTNGGNACNATHYTNTTYYTNCAYGGNGCNGCNTTYTCNTCNCARAAY TGGCARGAYATHGGNGCNATGGAYCARGTNGCNAGYTGGGGNTAYMGNGCNGTNGCNATH GAYYTNCCNGGNAARGGNAARAGYACNCARAGYYTNGARAARTCNYTNACNGAYAARTTY YTNCCNGCNYTNGTNAARACNYTNGARATHGAYMGNCCNATHATHGTNTCNCCNTCNATG AGY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYACN TTYYTNTTYGARGGNTTYGAYACNACNTCNAGYGGNGTNTCNTGGACNYTNTAYAGYYTN GCNTCNCAYCCNGARTGYCARACNMGNGTNTAYCARGARGTNACNGARGTNYTNGAYGGN MGNCARGAYATGGAYTGGAGYGAYATGTCNAARYTNGARTAYACNACNATGTGYATHAAR GARGCNATGMGNATGCAYACNGTNGTNCCNTTYATHGARMGNAARYTNAAYGARCCNYTN GTNYTNGAYGGNCAYGTNATHCCNACNGAYACNYTNGTNGGNGTNCAYATHTGGGGNYTN CAYCAYAAYCCNCAYGTNTGGGAYMGNCCNCAYGARTAYGAYCCNGARMGNTTY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYGARGAYAGYYTNTCN AAYTTYYTNGAYACNCCNMGNCARGAYGAYCAYTCNAARGTNCCNATGTCNCCNGCNAGY AARYTNCAYCAYYTNYTNYTNGARTCNCARGARATGATHMGNTCNYTNGARAARATGTCN NNNGARATGGARATHGAYYTNATHAAYMGNGAYCCNAAYAAYYTNAAYGAYCAYGTNNNN GTNTGYTTYGAYGARGTNATHGGNGARCCNGAYGGNGCNCAYTCNATHAAYTGYGTNTGG ACNAAYAGYTAYMGNTGYTTYAAYTGYTGGAARAGYTGYTGYTAYAAYYTNYTNACNATH TTYTGYGGNATHCCNYTNGCNATGTGYTGGGGNTGYGARTTYGCNGGNATHACNTTYTAY CAYGTNTGGACNGTNACNCCNTGYATGMGNTCNTAYATGATHCARTGYGGNTGYATGCAR AARTTYTAYGGNGCNTGYYTNCARTGYTGYATGCARCCNTGYTTYGARTCNATGGGNTTY YTNYTNAAYAAYATHAARGTNACNAARGTNAGY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATGTCNACNTCNAARATHTCNGCNAARGTNTCNAAY TGGAAYCARGARACNAARACNMGNYTNAAYGARAARATHACNTCNAAYGTNAAYGAYGTN GGNTCNYTNGTNMGNCARYTNATHMGNGGNTCNAARACNAAYGARTTYYTNGCNCARGCN GCNAARAAYTTYGCNTCNCARGARAGYTAYGTNMGNTCNCAR------------YTNGAR TTYCARCARTCNGCNATHTCNMGNAGYYTNCARCAYYTNGAYGARGTNCARGAY------ ---------------------------------CARYTNTCNACNYTNCARCAY------ ------------------------------------------CCNTCNGARMGNGCNTTY GARTGGTAYYTNGARAAYATGAAYMGNCCNGGNGAYMGNGTNGTNYTNGCNCAYTGYTCN CARTTYCAYYTNCAYATHGGNYTNCCNGGNGTNGTNGTNAAYGTNGARAAYGTNGCNAAR CARGTNGARGARTCNAARGCNAARGCNGAYAAYATHATGACNAARGCNATHGCNGTNYTN MGNGCNAARGAYATHTCNGCNTAYACNGTNGTNAAYAAYCAYTCNAARGCNCAYGARGGN YTNYTNAAYACNGCNGARGARGARAAYGTNGAYCAYATHGTNATHGGNAGYMGNGAYYTN GGNGCNGTNAARMGNGCNTTYGTNGGNAGYGTNAGYACNGARGTNGTNMGNCAYGCNAAR GTNCCNGTNACNGTNGTNAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARGAYGAYGAR GGNAARGAYGARAAYGARAARYTNAARGCNCCNACNGARYTNYTNATGGARTTYATHGAY TGYYTNATHMGNAARGAYTAYCCNAAYGCNAGYAARYTNTGYAARATGATHYTNYTNTAY GARCCNGARAAYGARGARGCNYTNAARTTYCARCCNYTNATHGARGARAARATGGCNATH GAYGCNGARGCNGARGARGARGGNAGYACNGAYGAYGAYGAYGAYGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TTYGARGGNTAYAARYTNGTNTCNGTNATHGCNAARTCNCARAARGARGTNCARTTY YTNCARGCNYTNGARGARGARTAYAARGARYTNGAYTTYTGGAAYGGNCCNTCNMGNTAY AARACNAAYACNATGATGYTNCCNCCNGAYYTNYTNACNCCNATHGARGARGCNATGACN MGNGARGGNATGACNTGGAARGARYTNGARGCNGAYGTNGCNAARATHATHGARGAYGGN ATGMGNTCNGCNCCNTCNGGNCAYMGNCAYATHMGNTCNGCNGAYGCNTCNGAYATHATH GAYCAYACNAAYTAYCAYGGNTAYCCNCARATHATHAAYTAYATGGARCARYTNGARCAR AARTAYCCNGAYYTNGTNAGYATHYTNTAYYTNACNTTYCCNTCNCAYGARGGNMGNAAR GTNGCNGTNATGAARYTNCAYAGYTCNAARYTNTCNTCNAGYAARMGNTCNATHGTNATH GARTCNGGNATGCAYGCNMGNGARTGGATHTCNCCNGCNGCNACNATGTAYAGYATHGAR AARYTNYTNCARMGNTAYTAYGCNGARATHAAYAAYGCNAARTTYATGGTNGAYTCNTTY GAYTGGTAYATHGTNCCNGTNACNAAYCCNGAYGGNTAYGARTAYACNMGNAARGGNCAR AAYACNMGNYTNTGGMGNAARAAYMGNMGNYTNATGAGYTGGAAYTGYCARGGNGTNGAY YTNAAYMGNAAYTTYGAYGTNTAYTTYGGNACNACNGGNGTNTCNAARGARTGYGAYTCN AAYATHTAYCCNGGNATGACNCCNTTYTCNGARCCNGARACNGCNAAYATHMGNGARYTN GTNMGNTCNYTNAAYGARTCNYTNGCNGTNTAYYTNTCNGTNCAYGCNTAYTCNCARTTY YTNYTNGTNCCNTGGGCNTTYTCNAAYGCNGGNYTNACNTCNCAYAAYAAYGARGARATG ACNCARYTNGGNACNCARATGGCNGAYGCNATHAARGGNACNCAYGGNAARATHTAYAAR GTNGGNACNYTNTGGGAYYTNYTNAARTAYGCNGCNAGYGGNTCNTCNACNGAYTGGGCN YTNCARACNAAYCCNGAYATHTAYGCNYTNGGNTTYGARYTNMGNCCNGGNGAYAARGAY GARMGNGGNTTYAAYYTNCCNCCNAAYGARATHATHCCNACNGGNCARGARTTYYTNGCN AGYYTNGARACNATGGCNCCNCARCAYGAYCCNACNAGYAARYTNTGYMGNTCNTGGYTN GTNCCNACNCCNCARCCNCARAARGARMGNGTNTTYTTYATHGCNTTYYTNACNTGYGTN TAYGTNTGYATGGTNATHGGNTGYGCNTCNGCNGCNMGNGTNGGNTAYYTNGTNAGYAAR MGNGTNAARCARGARATGMGNMGNACNACNMGNYTNTAYCAYCARGARGARGAYGTNCCN GAYATHMGNGARYTNTCNGTNYTNGAYGAYYTNAARMGNCAYCAYAGYYTNTCNTGYYTN GCNGTNTGYGGNATHYTNACNTGGYTNCCNATHGCNATHATGYTNACNYTNCARAARTCN GGNGTNCAYATHAGYGARGCNACNYTNGTNTAYTCNAAYATHGCNACNTCNYTNCCNTGY YTNYTNAAYCCNYTNYTNTAYAGYYTNGTNYTNGCNMGNTAYMGNGARGGNTAYAARGCN ATHYTNGARMGNTGYMGNMGNAARAARGGNCCNCARAARCCNCAYCARYTNMGNAAYGTN CAYCAYTGYTGYGAYCARGARATHGGNACNCAYAGYGAYYTNATHTCNACNTCNGAYGGN CAYMGNTGYGTNCAYGGNMGNCCNAAYCCNACNTTYGAY--------------------- ---------GGNMGNCARATGTGYTAYGCNTGYCARTAYGTNYTNAAYGGNCCNGGNATH GARTGYGTNACNGCNCCNYTNAAYTGGACNGGNGGNGTNGTNMGNATHMGNTGYCCNACN MGNTGYACNATHATGGCNGARTAYGAYGCNAGYACNGGNAARCCNACNTTYTTYCAYMGN GGNTGYGGNGTNGGNTCNGAYGCNCARGARGARGGNTGYAARGAYGTNGGNTCNMGNCAY AAYTGYTTYTTYTCNTGYGGNGAYGGNCAYGAYTAYTGYAAYAGYCARGCNYTNTCNMGN TCNCCNATHATGGGNCCNGGNGAYGGNTGYGGNGCNYTNMGN------------------ ---------------------------------GGNAARGAYTGGAARAAYGTNTAYTCN MGNYTNCCNTTYGAYCCNCCNMGNGAYCCNACNMGNYTNCARMGNGAYATHTCNGTNYTN GAYCAYATHGCNTAYMGNAGYGAYATHCCNCCNGARAARCARGCNYTNAARAGYYTNGAR MGNTGGMGNGCNYTNCAYMGNAARGGNGAYGTNAAYGARYTNATHCARGTNYTNMGNGAY GTNAARAARAARMGNYTNGCNGCNGARYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CARAARGCNTCNACNCCN GARATHGAYAARAARAARGAYMGNGAYMGNCCNCCNTCNAARATHGTNATHMGNMGNYTN CCNCCNTCNYTNACNCCNGARAAYTTYYTNGARCARGTNTCNCCNYTNCCNGAYCAYGAY TTYTTYTAYTTYGTNMGNGCNGAYATGAGYYTNGGNCARAAYGCNTTYTGYMGNGCNTAY GTNAAYTTYYTNAAYGCNGARGAYATHTTYATHTTYMGNGAYAARTTYGAYGGNTAYGTN TTYYTNGAYGARAARGGNGGNGARTAYCCNGCNGTNGTNGARTTYGCNCCNTTYCAYAAR GTNACNAARAARAARCARMGNAARYTNGAYTCNAARTGYGGNACNYTNGARCARGAYTCN GAYTAYAARAARTTYYTNGARTCNYTNGCNAAYCCNCCNGARACNCCNTCNGTNTCNYTN GAYGCNATHGTNGARGARGTNGARGCNAARGARYTNMGNYTNGCNAARYTNGGNTCNACN AARACNAAYACNCCNYTNYTNGARTAYYTNAARMGNMGNAARGARGARAARMGNATGAAY ATGGTNAARATGMGNGAYGARMGNMGNMGNGGN------AARGAYMGNGAYTAYGAYMGN MGNMGNTCNGCNAARGAYGARGGNGGNAGYGGNMGNAARGAYMGNGAYMGNGAYMGNCAR ATGGAYMGNGAYMGNMGNMGNGARMGNGCNMGNGARATGGCNMGNGARAARGAYMGNGAR MGNMGNMGNGGNMGNGCNMGNGARMGNAARAARGARMGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHCAYYTNACNGCNAARYTNGTNGARAAYTTYAARACNACNGGNYTN AAYTCNCARYTNMGNYTNATHGTNACNAAYGAYTCNAARGTNATHGTNTCNGGNATHGAR ATHAARYTNAARMGNTAYYTNACNTTYCARATHAARGAY------TGYGAYMGNGCNAGY YTNACNCCNACNATGAARACNGAYGGNATHGARATHYTNCCNGARTCNGGNCCNTAYYTN GTNTAYTCNATHACNGGNTGGTCNGAYTCNGTNATGAGYAARTTYGTNAGYGGNGGNYTN GAYCAYYTNCARATHCCNYTNGTNGARAARACNATHGARGGNGGNMGNAAYAAYYTNCCN CCNTCNGCNGARGGNAARAGYTTYAARAAYAARTAYGGNYTNGAYGTNTCNATHAGYTTY AGYAAYGGNCAYACNGARACNYTNAGYYTNGTNATHCCNGGNGTNYTNCCNTGYYTNAAY AARGARTGGTCNTCNTGGAARGCNTCNGAYTGGYTNTTYAAYTGYGAYACNAARYTNTCN GGNTCNYTNTTYTCNGTNGGNGARCAYYTNYTNTAYACNGARGCNTTYTCNAGYYTNCCN GGNTTYCARGTNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CCNGARCARATHMGNGGNGGNGGNGARYTNTTYAARTAYCCNTGGACNGCNTAY TCNAARGTNCARCARTTYCCNTTYAARTTYTAYTGGACNCAYTCNMGNYTNTTYMGNTAY TTYTTYTTYTCNTCNGCNYTNGTNTTYCCNYTNATGGTNAARATGACNAARGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNGCNGTNCCNAARATGMGNMGNACNYTNGARGGNGTNMGN GGNCAYCCNTAYACNMGNGTNTCNYTNTCNATGACNGARACNATHCARYTNYTNAARTGY GGNGTNMGNTTYTCNCCNCCNACNYTNGTNYTNACNTAYAARGAYTGGAARTCNGGNAAR ATGMGNMGNMGNTCNATGCCNYTNMGNAAYTTYACNAARCAYACNGGNGTNGARMGNGTN TGYCARGAYYTNAARGARAAYCCNMGNCAYGCNAARTTYATHMGNYTNYTNTCNCCNYTN CARYTNCARMGNYTNYTNACNATHATHAARGAYAARGTNAGYGGNYTNAGYYTNGARGCN AGYATHGCNMGNAAYAAYCARATGGARAARGTNGAYCCNGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------- >picta YTNYTNATHGCNCCNYTNYTNGCNGGNGTNGCNTCNGCNGGNTAYGAYCCNTAYACNGAY YTNACNCARYTNTAYMGNATGCARYTNYTNGCNGAYGCNTTYGAYGGNTAYATHCCNGAR GAYYTNCARYTNGAYAAYAAYGAYGTNGAR------ATHMGNTCNTAYTGGCCNGARYTN ---------------GAYGAYAAYGCNAARGCNCCNAGYGAY---------ATGTAYGGN TCNCARATHTAYAGYGGNGCNCAYATHMGNGAYCARGARCAYATHGARCAYAGYGCNYTN CAYGGNTAYCARTCNGTNGCNGGNGGNACNGCNGARGGNCCNGCNAAYAAYAARATHCAR AARAGYGAYAARCCNYTNCCNGCNTAYTGYAAYCCNCCNAAYCCNTGYCCNGTNGGNAAR ACNGCNAARGAYAAYTGYGTNGARGAYTTYGARAAYTCNGCNGARAAYAAYAARCARYTN YTNAGYGARCARGAYTGYCCNTGYGAYACNGARCAYATGTTYAGYTGYCCNGCNGGNMGN GARACNGTNTCNTCNAARGGNCARTCNGGNTAYCARCARACNYTNAAYAARGTNATHGAY CARYTNACNAARATGGGNGCNGARGAYGAR------GARAGYGAYGGNYTNATGGCNCCN ACNMGNAARMGNATHACNATGGTNGCNAARAARTCNCCNCAYATHATHCAYAARMGNTCN GARAARATGGAYGAYGTNAAYCCNTAYTTYGCNGGNACNMGNATGGAYATHGCNGCNAAR AARAAYCAYGARYTNGCNCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TGYAGYATHTGYTTYYTNATHGGNYTNATHCARYTNGGNGCNAGYGTNGARGAY AARTAYGARCCNATGGTNGCNTTYATHTGYGARMGNCCNGCNATGCAYMGNGGNGTNAAY GGNTGGATHGCNGAYAARTCNCARGAYTGYCCNGAYACNYTNCARGAYGTNYTNAAYTAY TGYAARAARGTNTAYCCNGAYCAYAAYATHACNAAYGTNGTNGARTCNTCNAGYTTYTTY AAYATHACNAAYTGGCCNATGGGNAAYGCNGGNMGNAARCAYACNCAYCAYGTNMGNCCN TTYMGNTGYYTNGTNGGNGGNTTYCARTCNGAYGCNYTNYTNGTNCCNCARCAYTGYGAR TTYGAYCAYMGNCAYGAYATHACNCARTGYAARGARTTYTCNCAYTGGAAYMGNGTNGCN GARGARGCNTGYGAYAARAARGCNATGCAYYTNGARTCNTTYGGNATGYTNYTNTAYTGY AAYACNYTNGGNCAYTTYAAYGGNGTNGARTAYGTNTGYTGYCCNAAY---------CCN ACNACNACN------MGN---GTNCARACNGAYGAYAARCCNGAYAARTGGAGYAGYTCN GARGARGAYCAYGARGAYATHGARGARGCNACNGARGGNGGNGARCARAAR--------- ------------------------------------------ACNAARGAYGCNAGYGCN CCNGCNTCNAAYAAYGAYTTYAAYCCNGAYGARAAYGTNGCNGAYYTNTAYGARGCNTAY YTNMGNGGNCARGCNTTYCCNTCNACNTAYGAYAAYGARCAYAARMGNTAYYTNGCNGCN AARGARMGNATGAARAARAAYCARAARAARAARGARGCNAARYTNYTNCARGARTGGGAR AARGCNMGNGARMGNGTNGAYGARGTNMGNACNACNGAYCCNAARACNGCNGAYAARATG AAYGAYGARATHGCNATGMGNTTYAARCAYYTNTAYGCNTCNTTYAARCARGARGAYGCN GCNGARAARCARCARYTNATGGCNYTNCAYCARCARCAYATHCARGCNTAYYTNAAYGAR MGNAARMGNGARGCNATGGAYAARTAYATGCARGCNYTNGARACNGGNGAYATHTAYAAR GTNATHAARTAYYTNCAYAGYTAYATHAARGCNGARGARAARGAYMGNATGCAYACNGTN AAYCAYTTYGARCAYATHMGNTAYTCNGCNCCNAARGARGCNYTNMGNATHCAYMGNCAY ATHATHAAYCAYYTNAARYTNTCNGARATGMGNATHGAYCARGCNATGGAYATGYTNACN CAYTAYCCNGARGTNGARMGNCARGTNMGNCCNGARATHGARGARTTYATGAARMGNTTY AAYGCNATHGCNACNAGYATHAARAAYGTNGTNYTNCCNGTNCCNGTNGTNGARGAYGAY ACNGARGCNGARACNAGY------------------GAYAGYAGYAAYACNGCNAGYAGY GAYGAYGAYATHAGYATHGAYGAYGGNGCNAARTAYGAYTCNAGYAGYGARGARGCNGAY AGYACN---------------------------------------TCNCARCARGCNACN GCNAAYGAYATHACNAAYGTNATHGAYGAYGARGTNCARGARGAYGARCAYAAYTAYGAY CAY------CAYTTYTCNGCNAAYGCNMGNGCNGAYACNCAYAGYGCNAARCAYGGNYTN CARTCNGTNGTNACNTCNGGNTCNCARATHGGNAGYACNGTNGGNATHGCNYTNGGNAGY GTNAGYGTNTTYGTNATHATHGTNGTNGCNGTNATGATGGTNCAYMGNAAYMGNAAYMGN CARTCNGTNGCNCAYGGNTAYGTNGARGTNGAYCCNTCNGCNACNCCNGARGARMGNCAY YTNGCNAAYATGCARATGAAYGGNTAYGARAAYCCNACNTAYAARTAYTTYGAR------ CARAARGAYAARYTNTAYMGNCARATHACNGTNGARGTNAARGGNCAYGAYCCNGCNGTN ATHAAYAGYTAYCARAARTTYACNACNACNGCNGCNGARCAYYTNGGNATHAARATHGAR AGYATHTCNGARCCNCCNAARGTNATHACNMGNMGNAGYYTNYTNAARTCNGTNTTYATH TTYAARAARCAYCARCAYCARTAYGARACNMGNACNYTNTTYMGNGTNTTYGARTTYAAR CAYYTNACNGARTCNACNGCNYTNACNTTYYTNGARTAYATHCARMGNAAYYTNCCNGAR GGNATGGCNATGAARGTNACNAARCAYGARYTNCAYCCNATHCCNGARCAYYTNAARCCN CCNGCNCARTCNCARTCNTCNAARCCNTCNCCNTCNGAYTAYTTYAAYGTNATGYTNGGN TCNCARYTNYTNTAYAARTTYGARMGNCCNCARTAYAGYGARATHYTNACNGARAAYACN GAYAARCCNATGTCNAGYATHTAYGGNGCNACNCAYYTNYTNMGNYTNTTYGTNMGNYTN GGNACNATGYTNGCNTTYACNTCNYTNGAYGARMGNACNGTNCAYATHYTNYTNAAYCAY GTNCAYGAYTTYYTNAARTAYYTNTCNAARAAYGGNCCNAGYYTNTTYAARACNTCNAAY TAYGARATHGCNACNCCNGAYTAYCAYMGNAARGCNATH---YTNGTNGAYTAYATHMGN TCNAAYTCNGAYCCNGAYGTNATHCCNMGNGCNTCNCAYGAYTCNCCNGTNAARGTNAAR GGNGGNYTNGAYYTNYTNAAYATHATHGAYGTNGAYCARGCNAAYAAYCARYTNGTNATG GARGCNTGGGTNCARTTYCARTGG---AAYTCNYTNATHACNTTYGAYCCNGARTAYTTY AAYAAYATGAGYYTNGTNMGNATHCCNGTNTCNGARYTNTGGGTNCCNGAYATHACNGTN TTYAAYGGNGAYTTYGTNATGGCNGAYGCNGGNATGAARCARTTYGCNGTNGTNTCNCAR GAYGGNGGNGTNTTYTGGGTNCCNAARACNAARATHMGNATHGGNTGYGAYYTN---GCN GARGAYYTNGTNAGYACNAAYGCNACNTGYACNGTNAARATGGGNTCNTGGACNCAYAGY GCN---CARGARYTNYTNGTNGAYGGNACNCCNGTNTTYGAYACNYTNAAYTTYGARGAR GAYTCNAARTAYGARYTNYTNGGNACNTCNAGYAARAARYTNGTNAARAARTAYTCNTGY TGYCCNAARGAYTAYGARAGYGTNYTNTTYACNTTYTCNTTYMGNMGNAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ACNAARCARMGNTGGATHCCNYTNGAR TCNAAYCCNTCNGTNYTNAAYAARTAYGTNCAYGGNYTNGGNATGGAYACNACNTGGAAY TTYGTNGAYGTNTAYGGNYTNGAYCCNGAYYTNYTNGCNYTNGTNCCNMGNCCNGTNGCN GCNGTNGTNYTNYTNTTYCCNGAYTCNAARTCNGARACNGTNGCNGARAAYCCNATHGGN GAYGTNATGAAR---AGYGTNGGNGAYYTNTAYTAYACNAARCARACNATHGGNAAYGCN TGYGGNACNGTNGCNATHGTNCAYGCNYTNGCNAAYAAYCARGAYYTNATHACNTTYGAY GARAAYAARCAYTTYTCNACNTTYATHAAYGCNACNAARTCNYTNAAYCCNGARGAYAAR GCNAARCAYYTNGARGARGAYYTNCARATGGGNGCNGCNCAYGARGAYTGYGCNCARGAR GGNGAYACNACNGCNCCNGCNGCNACNGAYAARGTNAARTGYCAYTTYATHGCNYTNGTN CAYGAYAAYGGNACNYTNGTNGARYTNGAYGGNGCNAARGARGGNCCNGTNAGYCAYGGN GCNTCNACNGCNGAYTCNYTNYTNGARGAYGCNGCNGTNGTNGTNAARAARTTYATGGAR MGNACNCCNTAYYTNAARGARMGNGAYGGNYTNYTNCARACNGAYMGNAGYACNMGNATH GGNCAYTCNYTNACNYTNACNGAYGAYGARAARATHGTNTCNGAYYTNATGGTNAARGAR AARMGNACNYTNATHGARAAYAGYMGNCARGGNMGNCARCCNTAYTAYCCNTCNTAYAGY TTYTAYAARTCNAARCCNTTYATGGARAAYACNACNATHTTYAARYTNATHAARCARATG CCNAARGGNGCNGCNYTNCAYYTNCAYGAYYTNGCNATHGGNAGYYTNGAYTGGYTNGTN ACNAAYGCNACNTAYMGNGAYAAYTGYTAYATGTGYATHGAYAARTTYTCNTTYATGAAY TTYAARTTYTCNAARAAYCCNCCNAGYGAYGCNGAYTGYACNTGGACNTCNGTNGCNGCN GCNMGNAGYTCNGCNCAYAAYGCNCAYGAYTTYGAYYTNAGYYTNAARAARAAYATGAGY YTNYTNGCNACNGAYCCNYTNGARACNTAYCCNACNATHACNCARATHTGGACNMGNTTY ATGCARTAYTTYGGNCARGTNCARGGNYTNATHTCNTAYGCNCCNGTNTTYAARGAYTAY TAYAARCARGCNYTNAARGARTTYTCNGARGAYAAYATHCARTAYYTNGARYTNMGNGGN YTNTTYMGNGGNGTNTAYGAYTTYGARGGNACNGTNTAYACNCCNGARTCNATHYTNCAR ATHTAYYTNGARGCNACNAARGARTTYYTNCARGARAAYATGGAYTTYTTYGGNGCNAAR TTYATHATGTCNGGNATHMGNAGYGAYACNGARAARTCNATHATGAGYGARGTNAARATG GCNATGGAYYTNMGNCARAARTAYCCNGARNNNGTNYTNGGNTAYGAYYTNGTNGGNCAR GARGAYCCNAAYNNNTCNYTNYTNCAYTAYNNNNNNGARYTNYTNNNNCCNAGYCARNNN NNNCCNNNNMGNGAYYTNCCNTAYTTYTTYCAYGCNGCNGARACNAAYTGGCARGGNACN GCNACNGAYTAYAAYYTNNNNGAYGCNATHYTNNNNAAYNNNACNMGNATHGGNCAYGGN TTYGGNYTNNNNAARCAYCCNNNNYTNGTNNNNGARATHAARNNNNNNGGNATHGCNGTN GARGTNAAYCCNATHTCNAAYCARYTNYTNGGNYTNGTNGARGAYCCNMGNAAYCAYGCN YTNGTNCCNYTNATGGCNGAYGAYYTNCCNYTNGTNATHAGYTCNGAYGAYCCNGGNTGY TGGGARGCNGCNCCNYTNTCNTCNGAYTTYTAYGTNGCNTTYATGAAYATGTGYGGNGAR GAYCAYGAYYTNMGNTTYYTNAARCARYTNGCNATHAAYTCNATHAARTAYAGYGCNATG TCNAGYCARGARAARGAYAGYGCNATGAARYTNTGGAAYATGCARTGGGAYAARTTYATH AAR------------TCNGCNCCNTCNGCNTCNAAYAAYCAYGARTCNCARAARGCNTCN MGNGTNAARMGNGGNAAYTAYGAYATGYTNMGNYTNACNMGNGGNYTNCAYATGYTNMGN YTNGGNAARMGNGGNGAYCCNATGGTNGAYGARGAYGAYGAYYTNTAYGCNCAYYTNYTN TAYACNYTNACNGAYCARTCNGARATGTCNCCNGARTAYAAYTCNCARTTYGAYAAY--- ------------------GGNGGNGARGAYGTNTCNTCNGGNATGMGNTTYMGNMGNTCN ACNCCNTCNGAYGAYGCNATGGTNACNCCNGTNCCNYTNYTNGARGAYGGNAGYGAYGTN ATGGAYGGNAAYTCNATGGCNYTNCCNGARGARYTNGARGCN------GGNGAYGAYGGN GCNAGYTGGYTNTAYCARGARATHGGNGAYGAYGGNGARATHGARGAYGGNYTNYTNGAY GARAGYAARMGNTCNYTNAAYATGYTNMGNYTNGGNAARMGNAAYYTNAARATGYTNMGN YTNGGNAARMGNGAYTCNGTNGARGARGAR------------------------------ ---------------------------AARMGNAAYYTNAAYATGYTNMGNYTNGGNAAR MGNAAYYTNAAYATGYTNMGNYTNGGNAARMGNCARYTNCCNATGYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CAYMGN ACNATGGCNGAYCCNAARMGNGTNCCNTGYGAYAARAAYGGNGAYAAYAARCCNATHACN AAYGGNGGNYTNTGGTAYTCNGTNGCNAARGGNATGCARGAYTAYAAYTAYYTNAAYACN AAYTGYTTYGARATHACNYTNGARYTNGGNTGYGAYAARTTYCCNCCNGGNTCNGARYTN GARCARTAYTGGGTNGAYAAYGTNGGNGCNYTNTTYAAYTAYATGYTNCARGCNCAYAGY GGNGTNAARGGNTTYGTNAARTCNAARAGYGGNGARCCNATHGARAAYGCNGARATHAAR GTNACNAAYYTNGCNACNGGNYTNCCNATHGARCAYGAYATHYTNTCNYTNGARGAYGGN GAYTAYTAYMGNYTNYTNGGNAAYGGNTAYTAYTAYATHMGNGCNGTNGCNCCNGGNTTY CAYGCNTCNGCNCAYTGYGTNMGNGTNACNAAYATGYTNMGNATHGGNGARACNGGNGAR GARYTNCARCCNGCNCCNATHYTNGAYTTYATHYTNACNCCNGAYTCNGARGARAARGAR GARAGYCCNAARGAYGAYGARATHTGYCARAARYTNTGGGAYGARGTNCARGARGARACN CARATHGAYAAYMGNGAYYTNYTNYTNTCNGTNYTNTCNTAYYTNGARCCNAGYTAYAAR TGGTCNTAYTAYGCNCAYMGNATGACNACNYTNCARYTNTAYTAYTAYYTNACNGARGCN YTNAARMGNYTNGARCCNGARGARATGAARACNGTNYTNCAYATGYTNCCNMGNGCNGTN CARGARCARYTNGARATGGTNATHATGGCNGAYYTNATHCAYAARATHTTYGGNCCNAAR CAYGGNAARAAYACNGARCAYGCNAGYAARCARTCNGARCCNGARGGNTAYACNAARCAY CARCAYGARTTYTTYAARGARTTYYTNGCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNYTNCCNACNMGNACNGCNGARGAYATHYTNCARGAYGCNTCNGGNYTNGTN YTNGAYAARMGNCCNAARTAYATGGAYACNMGNMGNGAYYTNGAYGTNTTYAARGAYYTN GTNYTNATGAGYATHCARGARYTNGCNGAYGARGGNMGNYTNGARTCNCARATHYTNCCN GARGARGARAARGAR------ACNAGYAARCCNGTNGARAARMGNMGNTAYATGGGNYTN TGYATGCAYMGNCARGCNAAYCARTTYATHCCNTTYCCNTGYYTNMGNGCNGGNMGNATG ATGAARGTNYTNTGYYTNGCNYTNYTNGGNTGYGTNGCNGTNYTNGCNGAYAAYTAYGTN TGY---CCNGAYATGGGNCARAARTTYGARTGYTTYGARTCNCARAARGAYTAYMGNGCN TGYYTNACNGAYGGNMGNMGNGAYAGYGCNMGNGTNGTNTGYGGNAARTGYACNMGNAAR TGGGARTTYTGY---ACNAARGGNAARATGGTNGARTCNAARCAYGGNGCNMGNGAYTGY GGNAGYGAYTAYAARAAYACNCCNTGYACNCCNCARAAYTCNTAYTGGTCNACNGTNTTY GTNTCNGTNGCNYTNGTNTGYCAYATHGCNTCNGGNTAYTCNATHTTYMGNTCNMGNATH CCNAAYGGNTTYATHGTNCCNAAYCCNTGYAAYCCNYTNGARACNTGGTAYGGNGTNGGN CAYYTNAGYMGNTAYGGNTCNGGNCCNMGNAAYAGYTTYGGNATHGAYTTYAARAAYGCN GGNYTNCARTGGACNGTNACNYTNTGYCARCARGAYTCNGAYGGNGAYGGNYTNACNAAY GGNGCNGARYTNGGNGAYCCNGAYTGYGTNTGGTCNGTNGGNATGACN---GCNACNTTY GAYAAYGTNACNCAYCCNGGNATHAAYAAYAAYAAYCCNGTNTGY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AARAAR GTNMGNGARTCNAARGGNGAYTAYGCNTTYYTNYTNGARTCNGCNATGAAYTCNTAYCAY GCNCARCARGARCCNTGYGAYACNATGATGGTNGGNGAYCCNYTNGAYAAYAARGGNTAY GGNGTNGCNACNTAYATHAAYTAYCCNYTNMGNCAYAAYATHAAYATHGCNGTNYTNACN YTNGARGARAARGGNGARYTNATHAARYTNCARCARAARTGGTGGYTNGAYAARGGNCAR TGYGGNGAYCARAGYCCNGGNAARGARTCNACNGGNACNCARAGYGCNYTNACNYTNAGY AAYGTNTCNGGNATHTTYYTNYTNGCNYTNYTNYTNTTYGCNGGNACNACNTGYGCNGTN TTYTAYATHCCNGGNTCNGTNGTNAGYTAYCCNAARATGGGNAARMGNGCNTTYTAYACN AAYGCNACNGGNAAYMGNTAYCCNYTNATGGGNMGNMGNTCNTCNCCN---------CCN GAYCARGAYGTNGARGCNAARGAYAGYGTNATGGGN---GCNATGATHCARGAYGGNACN GARTAYAAYAARMGNGGNGTNTTYACNCARGGNCCNCAYMGNAGYTAYCCNMGNGTNGGN MGNGCNGGNAAYACNGARGARTCNTCNCCNATGACNGTNGAYGGNMGNATHMGNGCNGAR ATHYTNAARGGNYTNGCNTCN---MGNGAYGGNAGYGAYGTNACNAGYYTNGGNGARGAR TCNGGNGARAGYAAYTCNTCNAAYGAYGTNCARYTNCCN---CARTTYYTNTTYYTNATH TTYGAYGARGAYGGNGAYAAYCARYTNAGYAARTCNGARTTYTAYGCNGGNGTNGCNAAR ATHGTNGARCARAAYYTNYTNTGY---------------CCNATGACNTCNCCNGAYGAR CCNGTNAARGTNTCNATHGAYATGTCNATHAARGCNGTNAGYAARGTNGAYAARACNACN AAYAARGTNGARATHGARGTNTGGCCNGCNATGACNTGGAAY---GGNGTNACNTTYGAY CCNGCNGAYTTYAAYGGNYTNACNGGNGTNMGNATHCCNGTNTCNGAYGTNTGGGTNCCN GAYYTNGCNGTNTAYAAYGGNGAYYTNTCNATHGTNGARAAYTTYGGNGARAAYCARGTN ATHATHAGYTAYGAYGGNCAYGCNACNTGGGTNCCNCAYACNMGNATHCAYGTNCARTGY GAYYTNGCNGAYGAYATGATHGCNAAYAAYACNACNTGYACNATHAARYTNGGNTCNTGG GTNTAYAGYAGYAAYTCNYTNACNYTNGCNGARAGYAAYGAY---TTYAAYTTYATGGAY TAYTTYGARGGNTCNAARTAYGARATHATHGAYACNTCNTCNGTNMGNCARGTNAARACN TAYAGYTGYTGYCCNGARAGYTAYGARAAYATGATGTAYACNTTYTCNTTYYTNGARAAR AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGYYTNYTNACNYTNGTN GTNACNYTNYTNTAYACNCCNGGNCCNGCNGCNGCNAAYTAYGARCAYTAYTGYGAY--- TCNTCNTTYMGNTCNCARMGNAAYGGNMGNTGYGGNGARAAYYTNGCNTCNACNATHYTN AAYYTNTGYGARGCNYTNTCNAAYTCN------TTYYTNAGYAARTAYATHATGAARMGN MGNCCNYTNGAYGTNGGNAARMGN---YTNCAYGAYATHAGYYTNAGYAARAARGAYGCN YTNTCNTAYYTNTCNAARMGNCARGGNAGYCARAAYATHGTNTGYGARTGYTGYGTNATH MGNTGYAGYTTYACNGARATGTAYCARTAYTGYGARYTNCCN------------CCNMGN TTYGTNGGNAARMGNGCNGCNCCNMGNTTYGTNGGNAARGARGARGAY------------ ------AARMGNATHCCNMGNTTYGTNGGNAARMGNGGNGTNCCNMGNTTYGTNGGNAAR MGNGGN------------------------------------------------------ ---CCNMGNTTYGTNGGNAAR---------------------MGNGGNGCNCCNMGNTTY GTNGGN------------------------------------------------------ ---------------------------------------------------------AAR MGNGGNAAYCCNMGNTTYGTNGGNAARMGNGGNATHCCNMGNTTYGTNGGNAARMGNGGN GCNCCNMGNTTYGTNGGNAARMGNGGNGTNCCNMGNTTYGTNGGNAARMGNGGNCCNCCN MGNTTYGTNGGNAARMGNAAYCARGAYGTNGGNAARMGNGAYGARGAYGAYGAYTTYGAY ATHAAYGAYTAYATHGAYTCNTAYAAYAAYGTNTAYGAYAARMGNGGNATHCCNMGNTTY GTNGGNAARAARTCNGCNAGYMGNYTNCARGARAARGAYGTNCARTCNATHYTNCAYAAY TGGAGYMGNCARCARGCNATHAARGARYTNAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR YTNGTNTAYGAYMGNGCNTAYYTNATGGARYTNMGNGGNTGYGTNTCNTCNCARACNAAR CCNGAYGGNYTNCCNGCNYTNGARGTNATHYTNGAYMGNCCNAAYCCNACNTCNATGTCN MGNCCNTCNGGNGGNCCNGCNGAYTTYACNCCNGCNTTYTTYCAR---ACNGTNACNAAY CARMGNCARGTNCCNCCNATHGGNAARAGYAGYAGYMGNGGNMGNCCNMGNCCNGGNGAY ATGCCNGGNACNCCNMGNATHATHAARAGYATHTCNATGTCNAAYGAYACNAARTCNYTN CAYCARGCNGARAAYCCNTGGAAR---------CCNACNAARAARGARGAYAARAAYGAR ATHAARACNYTNGARGGNGARATGYTNTTYATHATGAAYMGNYTNACNCCNACNAAYTTY GARAARATGGCNGGNGARATGAARAARYTNAAYGTNAARACNTAYGARGAYYTNACNTCN ATGGTNAARATHTTYTTYGAYAARGTNACNATGGARACNAARTTYGTNGARGCNTAYGCN YTNYTNTGYAARGTNATGTCNGTNYTNMGNGTNACNCCNCCNACNGAYGGNACNGTNAAR GARCAYATGGCNACNTTYMGNGTNGTNATGYTNACNAARTGYCARCARGARTTYGARGCN GAYAARTCNATHATHTTYGARGAYCCNGARGARAARMGNAARAARYTNGARGCNGARAAY CCNGARAARACNCCNGARMGNAAYGARATGATHGARAARACNYTNTAYCAYATGAARYTN AARMGNATGAARTTYTAYGGNAAYATHMGNTTYATHGGNGARYTNTTYAARYTNGGNATG YTNACNGARAGYATHATGCAYGAYTGYATHTTYMGNYTNYTNAARGCNMGNGAYGAYGAY TCNYTNGTNTCNYTNTGYAAYYTNYTNACNACNGTNGGNMGNAAYYTNGAYACNGARAAR GCNAARCCNMGNATGGARCARTAYTTYTCNCARATGAAYAARATHGCNGAYGARMGNAAR TCNMGNATHAARTTYACNYTNMGNGAYGTNATHGAYYTNMGNTCNAAYCAYTGGGTNCCN MGNAARGARTCNACNGGNCCNAARAARATHGAYGARGTNCAYAARGAYTTYGCNCARGAR CARGCNMGNAAYCARTTYYTNGCNAGYCARCCNCCNCCNCCNMGNAAYGAYAAY---CAR GCNGGNAGYMGNMGNGGNAGYMGNCARMGNCARGAYGAY---MGNTCNAAYGAYGARGGN TGGAAYACNGTNAGYTCN---AARTCNGTNMGNGTNATHGAYGCNTCNAARATGAARATH TCNAAR---AAYGTNGTNGAYGAYAAYATHCARYTNGGNCCNGGNGGNGGNGTNCAYAAR CARGCNATHTGGAGYMGNGGNAGYCAYGGNGGNGCN---CARCCNTCNCARGAYGAYMGN ---GCNCARGGNTCNAAYMGNTTYTCNGCNYTNACNAAYGAYGAYGCNMGNMGNTCNTTY CCNMGNTCNCCNTCNMGNGGNGARGGNTCNGCNGCNMGNAGYATHMGNCARGGNCCNACN GCNGGNCAYGGNMGNGGNAARATHATHACNMGNTCNAGYCARGARGGNGARMGNMGNACN GCNATHGCNAAYGCNMGNTCNTTYATGGGNGGNMGNTCNCARAAYTCNAGYMGNGAYAAY AGYTGGAAYMGNGAYGAYMGNMGNCARTTYATGGGNCCNMGNAGYTCNTTYGARMGNGAY AAYCCNATGACNMGNAGYGAYAGYGCNGTNMGN---ACNGARGARTTYMGNGCNCCNGCN CCNCCN------GCNGTNAARCARATGACNGARTCNGARATHGARACNAARGCNATHAAY ATHYTNGAYGARTAYYTNAAYATHMGNGAYYTNACNGARGCNAARYTNTGYATGAARGAR YTNGGNGGNCARAAYCAYATGCAYYTNGTNGTNACNGCNAGYATHAAYAAYGTNYTNGAR AARMGNGAYGAYGCNMGNCAYATGACNGGNAAYTTYTTYCAYGARATHGTNAGYAAYGAY YTNYTNACNGCNGAYATHTAYATHAARGGNYTNGGNGARGTNYTNCARTAYGCNAGYGAY ATGGTNGTNGAYATHCCNAARYTNTGGAGYTGYYTNGCNCARGTNATHTGYCCNYTNYTN ATHGGNGGNTCNYTNCCNTGGTCNAARYTNAARCARGCNTTYACNCCNCAYYTNGAYAAY AARGAYGGNGCNAARYTNYTNGCNTCNATHYTNTCNCARTGYGTNGARAARCARGGNGAR MGNGARGTNGTNCAYCARTGGCARAAYAGYGGNYTNAGYTGGTCNTCNTAYYTNAARGCN GAYGARGTNAAYGAYTTYGTNAARGAYAARAARGTNGAYTTY------------ACNATH GGNGCNTCNTCNGCNAARCCNCCNACNGGNAGYGGNYTNGAYAARYTN---------GCN GAYYTNGARAARATGATHMGNAGYCARGTNTCNAAYACNGAYYTNATHTCNTTYATHGAR MGNTCNGTNCCNGGNAGYAARACNGAYTCNAAYTTYATHMGNGCNYTNACNACNGCNTTY GTNAAYGCNGCNATHAAR---------GARAAYAARAAYATHGAYGARGAYATGATHAAR AGYCAYAARGAYGTNYTNCARAARTAYATH---GGNAAYAARGTNGAYYTNCARYTNCAR GCNYTNTAYGCNATHCARACNYTNATGGCNAARYTNGARCAYCCNTCNGGNGTNYTNYTN AARYTNTTYGARYTNYTNTAYTAYGARATHTCNGTNGARGARGAYGCNTTYTAYMGNTGG GARAARTGYAAYGAYCCNCARGARCARGARAGYAARGGNTCNTGYYTNATGCARGTNMGN CARTTYTTYATHTGGYTNMGNGARAAYGARGAYCCNGAR---------GGNATHGCNGGN GAYGCNCARGTNATHACNAGYACNGGNYTNAGYGCNCCNGCNGAYYTNGAYGGNCAYYTN GAYACNAGYTTYTAYCCNGGNGTNTCNGGNCCNGAYAGYTGGTTYGAYGAYYTNGAYGAY ---------YTNTCNGGNGAYCCNYTNGGNGAYGAYAGYATGGARTCNTTYATHAAYYTN GAYAARTTYYTNAAYGGNAAYTCNTTYTTYGAYGAR------GAYGGNAAYYTNAAY--- GTNCCNGAYGARGCNGCNGTNACNCCNGTNATHGAYTTYGARCCNCARGARATHGTNTCN GTNTCNGAYCCNACNGTNCCNGTNYTNGAYGARCARCARGAYTTYYTNYTNCCNGTNGAR AARCCNGCNMGNAARMGNTCNGCNMGN---AARATGGARGGNATHAARACNAGYYTNTAY GARATHCCNACNTCN---------------GTNATHCARGTNGARTCN------GARMGN GTNGCNAARGAYATGGARYTNGAYCAYGAYTAYAGYTCNAARMGNCARMGNATGTCNGTN CCNGTN---------------------------AAYMGNAAYACNACNAGYGAYACNATG AARGTNTTYACNGTNGGNGARAARGARATHTCNCARGCNAGYACNTCNTCNCCN------ AAYAAYGGNCARGGNYTNAAYGAYAGYGTNGAYAARCARACNATHMGNMGNATHAARAAY AAYCAYGCNTCNAARMGNTCNMGNGARCARMGNAARCARAARTTYGTNGAYATGGAYGCN GARTCNGARGARYTNATHTCNMGNAAYCARGARYTNMGNCARAARATHGTNGARYTNGAR AARYTNGCNAARGARATGAARACNYTNYTNGTNGCNAARATGGCNGGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGGCNGAYAAYGCNGTNGAYTCNACNAARAGYGARGARGAYGGNGCNGAY GCNGCNGAYACNAARGTNTCNTCNTCNTTY---------GGNGCNCARAGYMGNCARTAY TCNGAYTCNACNTTYTCNTCNACNAAYGAYGGNAAYCARGARGTNAGYAGYTCNGAYATH ACNGARTCNGGNTGYYTNGCNCARGCNCCNAARGTNCCNAGYACNTCNGTNAGYTCNTAY AGYAAYGCNTTYTAYGGNAAYTCNCAYAAYGCNGCNATGTAYACNAAYCCNTTYGTNCCN MGNGCNCCNYTNAARTCNGAYGTNGTNTCNACNCARTCNAGYAGYGGNGAYAAY---MGN GARAGYYTNATHGCNCCNAGYMGNYTNAAYGCNGCNGTNAAYMGNGAYAGYTCNGARGCN GARGGNGAYMGN------AGYTTYCCNAARCARTCNATGYTNGCNCCNCCNAARYTNACN GGNGCNGTNTTYGGNGGN------GCNMGNCARGAYACNCCNAGYTCNACNTTYAAYTCN TTYAAYTCNTTYAAYATHMGNCCNTCNGTNTTYTCNAGYCCNTTYGAYGCNCCNYTNYTN AARCCNGCNTCNCCNYTNYTNAARCCNGCNAARYTNCCNGAYCCNACNAARTCNTGYGAY GGNAARGCNGAYTCNCCNAGYGARGCNGAR------GTNYTNTGYGCNACNGCNAARTCN GGNGARGCNGCNCCNGTNAGYGAYMGNYTNGGNGGNGTNGAYGGNGCNTCNGGNGGNAGY GARGTNTCNTCNTCNTCNTCNACNCCNGCNTCNACNYTNCCNCCNCCNCARACNYTNCCN GAYGCNGARGGNGCNGTNGGNGGNGARAGYACNCCNTAYAAYCARGAYATHGTNCCNGAY ATHAAYAARAAYAAYMGNYTNAARGAYTCNTCNGGNGTNTCNAGYAGYTCNCARTCNTTY GTNTTYGGNAGYAAYYTNTCNCARMGNGTNACNGGNATHYTNTCN---TCNCCNTGYGAR AAYGARGCNCCNGCNTCNTCNGGNTTYGTNTTYGGNGARTCNYTNGGNTCNMGNGCNACN GTNGARACNAAYGGNTCNGCNCARCCNACNAARGAYGARGARAGYGAYTCNGAYTGYGGN AAYAARYTNAAYCARACNYTNGARGARTCNGCNMGNGARTAYCARGCNAARCAYGAYAAY MGNACNGARYTNAARGARGTNGARACNATHACNGGNGARGARGARGARTCNAAYGTNYTN CARGCNAAYGCNAARYTNTTYTTYTTYGARACNAGYAAYGARTCNTGGGTNGARMGNGGN MGNGGNACNATHMGNYTNAAYGAYATGTCNGCNMGNGAYAAYACNAAYTTYCARTCNMGN YTNGTNATGMGNACNCARGGNAGYYTNMGNGTNGTNYTNAAYGCNAARATHTGGCCNGGN ATGTCNYTNGARMGNGCNTCNACNAARTCNATHMGNATHACNGCNATGGAYACNGAYGAR TCNATHMGNATHTTYYTNATHACNACNACNACNAARGAYTCNGARAAYYTNYTNMGNGCN ATHGAYTGGMGNATHCARCARYTNAARATHCARGARGARCCNGTNMGNTCN------GAY GCNMGNACNGGNGAYAARMGNAARGCNGAYGAYTCNGAYTTYGARYTNCCNYTNAARAAY AARAARGTNAAYAGYTCNCCNGAYCARGGNATHTCNATHACNAARAARGARGARTCNGAY AGYAGYGTNCARGAYCCNGARACNGARGCNTCNTGYGARAGYCAYTCNTCNTCNYTNACN ATHAARTCNGARTCNGAYTAYCARTGYATHCAYTGYGGNTGYCCNACNGAYAARYTNTAY CAYGAYTAYAARGCNGGNATHACNAARGTNACNAAYTGYGAYGTNTGYGGNAARATHGTN GAYAARTAYGTNGARAAYGAYACNGCNATHATHYTNYTNGAYGTNYTNYTNYTNCARMGN CCNGCNTAYGCNCAYYTNYTNATHAAYATGCARGTNAARTCNCAYTGGAARTCNGCNGTN YTNYTNTGGGTNGTNGARGCNTTYGTNAARYTNATHCARCARMGNTCNGARCAYGGNGCN TCNYTNCAY---------GARGCNGAYGTNTAYTCNATHGTNGGNGTNGARYTNTAYYTN AAYTAYATHGTNGCNGCNGTNGAYYTNATGAGYTTYYTNYTNTGYGTNYTNGCNGTNYTN ACNGTNMGNAGYYTNYTNYTNACNGGNAGYYTNAARYTNYTNAAYACNTTYTTYATHACN AARGCNGTNYTNYTNGCNAAYYTNGGNTCNGTNYTNGCNATGCCNGCNYTNYTNTGGGGN AARTCNTAYAGYTCNYTNYTNGTNTGGYTNGGNCARGCNTTYGTNTGYYTNTCNTCNYTN CARGCNYTNMGNGTNGTNATH---YTNGGNCCNCAYAARAAYATHTTYGCNGTNYTNGTN GTNATHTGYGGNATHAGYTTYCARGCNATHATGTCNGARGCNYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGCNTCNTCN AAYYTNTCNMGNACNGTNGTNAARTCNYTNCARGGNMGNTCNTTYGCNGCNGCNGCNGCN GCNCARGCNGAYMGNGGNCAYAGY---------GAYAGYMGNTGYTCNGTNAARAARYTN AGYAAYGGNATGTCNGTNGGNGTNATHCAYTCNAAYTCNCCNGTNGCNMGNYTNGCNGTN GTNGCNAAYGCNGGNTCNMGNTTYGARAAYGGNGAYAAYYTNGGNGTNTCNCAYTTYYTN MGNATGTCNTCNMGNYTNMGNACNGARAAYATGTCNAGYYTNGCNATGACNMGNACNGCN CARCARYTNGGNGGNGAYGTNACNATHATGGGNACNMGNGARTAYATHTAYTTYAARAGY GGNGTNACNMGNAAYTGYACNGARAARATGGTNCARYTNYTNCARGARYTNACNACNAAR CARGTNTAYACNCCNTGGGARGTNACNGAYGTNCARCAYGAYAARGAYGGNATGYTNYTN GAYYTNGCNYTNTAYCAYACNMGNCCNCAYGTNMGNGCNGTNGARYTNYTNCAYTCNGCN GCNTTYMGNTCNACNYTNGGNAAYTCNYTNTAYGCNCCNGGNCAYAGYGTNGGNTCNTAY ACNCCNGARCARGTNATGCARTTYGTNAARACNTAYTTYAGYGCNGGNMGNATGGCNYTN ATHGGNATHGGNGTNGAYCARGCNCARATGGARGAYYTNGCNTCNCARTTYGARCCNTTY GCNTCNGCNGGNGTNCCNGARGARAARGCNGTNTAYCAY---GGNGGNGARATHMGNAAR AGYATHGGNGGNGAYGTNTCNTAYGTNGCNGTNGGNTGYGGNGGNCCNGGNYTNAAYAGY AARGAYYTNYTNGCNGCNGARGTNYTNMGNCAYATHATGGGNACNGGNCCNCAYATHAAR TAYAGYAGYGGNACNGTNGGNGCNAAYYTNGCNAARGCNGCNGCNGARGCNACNAAYGCN CCNTTYCAYGTNTCNTGYYTNAAYGCNACNTAYACNGAYAAYGGNYTNTTYGGNTTYACN GCNGTNGCNCAYGCNTCNCARATHGARAARGTNGTNCARGCNGCNGCNAAYCARTTYAAR AGYGCNGCNTCNGCNAAYATHTCNGAYCARGAYATHGCNMGNGGNAARAAYCARYTNAAR GCNGARATHTGYATGCARTTYGARAAYCCNGAYGTNYTNYTNAAYTGGYTNGGNGARCAR GCNYTNAGYGGNGARGARGTNATHACNCCNGARGAYGTNTAYAARATGGTNGAYGGNATH AAYGCNAAYGARGTNAARAAYGTNGCNAARACNATHYTNAGYTCNMGNCCNTCNATGGCN TCNATHGGNAAYATHGCNAAYGTNCCNTAYYTNGAYAARYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CCNCCNAAR GARGARGARCCNGCNGCNCCNGARCCN------------CCNAARGCNGARGARCCNGCN CCNGCNCCNGTNGAR---------GARAGYAARGTNGARGARGCNGCNCCNGARAARGTN GARGARCCNGCNGCNGARCCNGCNGCNAARGARGARGARCARCARCCNGAR---CCNGTN TCNGARCCNTCNGCNCCNGAR--------------------------------------- ------------------------------------CCNGTNGCNACNGARCARGARACN GTN---GARGCNCCNGCNGCNGARGARGARCARGTNYTNACNMGNAARAARACNATHCCN AARYTNGCNCARACNGTNAARGCNGCNMGNGGNATHYTNCARTTYTCN---TCNAARGAY AARGARAGYCCNCCNTCNGCNAGYGARGARAGYGCNCCNGCNACNCCNTCNGARACNGCN GARACNGGNGCNGCN---------GAYGGNTCNGCNGCNGARACNGGNGARACNGCNGCN CCNAGYGARGARTCNGCNCCNTCNACNGTNMGNACNGARTTYAARTGGGARAAYGGNGGN GARGCNGTNYTNGTNAGYGGNACNTTYAAYAGYTGGCARGARAARATHGCNYTNTCNAAR GARGGNGAYGTNTTYACNGGNTTYATHGAYYTNCCNGCNGGNGARCAYYTNTGYAARTTY ATHGTNGAYGARGARTGGGTNGTNAAYAARAAYYTNCCNATHAARYTNGGNGAYGAYGGN CARGARAAYAAYGTNATHTCNGTN---------AARYTNGGNCAYTAYYTNATHTGYTGY CARGTNTTYATHYTNTCNYTNTCNGCNGTNGGNAAYTTYCARYTNTTYGTNTCNAARCAR TCNYTNAARTAYTGGGAYGARGAYGCNTCNGTNATHGGNTGYTTYYTNTGGGAYTTYGCN YTNATHTGYYTNTTYATHGGNCARCAYTCNYTNATGGCNACNACNTGGTTYAARTCNMGN YTNCAYTCNTGGYTNAGYGTNACNGTNTCNGARMGNYTNGTNTAYYTNTGYGCNACNTCN ATHTGYYTNATGGTNATGATHCARTAYTGGTAYTCNATHCCNGAYGTNTAYYTNTGGTAY ATHGAYACNCARGAYMGNACNTTYYTNTGGACNTTYTTYTTYYTNTGYCAYTGYGTNGGN TGGGTNGTNYTNGGNYTNGARYTNATGYTNGTNGAYYTNGGNGARYTNYTNGGNTTYAAR CAYGTNTAYAAYTAYCAYAAYAGYYTNYTNCCNCCNTTYTTYGGNAARAARGCNACNCAR YTNMGNGARATHTAYTCNMGNATGMGNCAYCCNGGNGTNGTNGTNYTNAGYGTNYTNYTN TGGTTYCAYCCNYTNATGACNYTNGAYMGNGCNYTNYTNGCNTCNATHTTYACNTCNTAY ATGGTNTGGMGNCAYAGYTTYGARGAYGTNCAYTGYGARTAYGCNGARAARCAYTTYTAY TCNGARGTNACNCARMGNAARTCNMGNAARTCNGTNMGNTAYGARTAYGTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GCNGCN TTYATHCCNGGNATGATHTCNAAYCARGAYTAYATGGTNGCNCCNTAYCAYAAYTCNGTN TCNCARTTYTGGYTNATGGTNTGGMGNYTNAARTCNCCNGTNATHYTNAGYYTNTCNCCN AGYACNGAYGGN---------GARAAYGTNTAYTGGCCNGCNGCNATGAAYGARGCNACN TGYTAYGARGGNGTNGTNATHAARYTNAARGAYGTNGCNCARCAYGARGARYTNACNATH MGNACNTTYMGNGTNACNGTNGGNAARGTNAGYYTNTCNGTNACNCAYATHGAYGTNAAY GAYTGGCAYAGYGGNAAR------YTNTCNAARGARGARATHATHAARYTNGTNMGNYTN TTYMGNAARGARGTNGGNYTNGARAARACNGGNGTNCCNGTNATHCAYGGNAGYGTNGGN ACNGARTTYGTNGGNTCNTTYATHGCNYTNGAYCAYTTYATGCARYTNATHGAYMGNCAY CCNGAYGAYGTNGTNATHGAYGTNTTYCAYTAYGTNYTNACNYTNTGYMGNYTNMGNCCN CCNMGNYTNGTNAAYGARTTYCARTAYGTNYTNATHCAYGARGTNYTNYTNGCNTTYATH AAYCARATGGARAGYGAYATHGARATGATHMGNYTNTAYCARCCNCCNTCNCAYTGYCAR GAYGAYMGNTGYGARGAYATGYTNYTNACNTTYYTNTAYTGYATHGGNATHCCNGCNATH YTNGTNGCNATHTTYYTNGTNATHYTNACNAGYATHATGTGYTGYTCNMGNAARGCNTGY ACNTGYAARAARTAYTCNTCNYTNACNACNGARTGYAAYGAYATHCARATGGARAGYTAY AAYACNATHMGNACNGCNTCNGCNAGYYTNMGNCAYATGTCNCARAAYMGNGARACNTCN GTNGARGGNAGYMGNTCNGGN---TCNATGACNYTNGAYMGNTCNTAYMGNMGNACNMGN MGNGGNMGNGARTCNTGYAGYTCNGCNCCNGGNACNYTNCARMGNCARCAYMGNAAYMGN CAYTCNGAYYTNGTNGARCARGCNCCNCCNCCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNYTNAAYAARTGYTTYGCNAARGTNGAYAAYCCNAARYTNAGYCARGGN GCNAARAARGGNTGYYTNTGGGCNYTNAAYCCNGCNAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AGYAAYCCN TTYCCNACNGAYTAYTAYGTNTGGYTNGAYGGNGGNTAYGGNCAYGGNGAYCCNGAYATH TAYCCNCCNGAYGGNATHTGGCAYCCNMGNCAYYTNYTNGCNCAYCCNGAYAARGTNACN TTYATHGCNTTYGARGCNYTNACNGARMGNAARAARGARGTNGARACNYTNCAYAARATG AARACNGCNTGGATHGCNGGNGGNYTNTTYGCNGGNGGNAARATGGCNATGGARMGNTTY TAYCAYYTNCAYAARGARATGATG------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GTNTAYTAYTGYCAYAGYCARGGNGGNAAYCARYTN TTYMGNATHAAYACNAARGGNCARYTNGCNYTNGGNGARMGNTGYATHATGGCNGARAAY GARGAYACNYTNCAYATHCAYGTNTGYGCNATHCARCCNGAYGGNCCNTGGGARTTYGAY AARGCNACNGGNGCNATHMGNCAYACNAARYTNGAYAARTGYGTNGGNACNACNATHGAY GAYAARYTNCAYGTNCARCCNTGYGAY--------------------------------- ------------------TGGMGNACNAARTGYATHAARYTNGARAARGTNATHAARACN YTNTCNAAYCAYTGYGTNMGNGTNGTNGARAAYCAYGARGAYYTNYTNGTNAARTTYAAR AARAAYCARGAYCARTAYGCNAARYTNAARACNAGYTTYGARGARAARGGNCARCARATH YTNAARGCNMGNGAYGTNYTNATHMGNGTNTCNAAYGARTCNAARTCNATGMGNGARAAR TAYCARATHGCNGTNMGNTGYCARATGGARGCNGARACNTTYGCNGTNAGYACNAGYACN AARAAYAARGARYTNAARMGNCARAGYCARATGYTNYTNACNAAYYTNGGNGCNGCNAAY ATHGTNGAYATHGAYATHGAYAGYYTNGARAARGARGAYGARGARGARAARGARTAYATH GCNAARYTNGAYCARCARATHGAYGARYTNGARGARCARAAYAGYGTNYTNAGYYTNCAR GCNAARGARYTNACNGARAAYTTYCARGTNGARAARGARGCNAAYGARAARYTNMGNGAR AARATHGARYTNATGAARACNGARYTNAARCARACNAARYTNGTNACNATHGARCARGAR AARYTNYTNCARCARGTNGCNACNACNTCNGARAARGTNTAYAARGARTAYAAYGAYATG GARCARACNTAYAARAARGARATHGTNGTNMGNAAYGARGCNGARMGNGCNGCNTCNMGN YTNTTYGTNGARMGNGARCARGCNMGNMGNGARAGYACNATGGCNYTNAGYCAYGTNGCN GAYAAYAARAARYTNATGGAYGCNATGYTNGARATHCARGAYYTNACNGCNAARTCNATH CARGTNAARGARGAYTAYGAYMGNMGNATHGARGCNYTNGARGARCARYTNAARGTNGTN AARGARGTNTAYAGYGTNGARGGNGTNCARGCNGARAAYGARGARYTNACNGARGARAGY YTNCARYTNAARGARMGNYTNAAYAARACNGARACNGARTTYAAYYTNYTNMGNACNCAR TTYTCNGARYTNYTNGARAARCAYAARGAYYTNGARATHAARTAYGARAARGCNACNCAY ATHCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNYTNCCNACNGTNAARTCNGGNGGN TTYYTNACNAARYTNGTNGGNMGNAARGGNCARMGNGARAARGCNAARGARCARYTNAAR AARGGNGGNGTNACNATGGAYGAYAAYCAYTCNAARGCNGTNGAYGARATGATGAARMGN ATHAARAAYGGNAAYGTNGGNYTNAARCCNGTNYTNCARMGNMGNACNACN--------- ------CCNGARCARGARGARGCNAGYGCNATGACNGARYTNCARGGNYTNYTNTCNAAR ATGAARCCNTCNMGNAGYGARGAYGAYYTNTCNGTNTTY---GGNGAYTCNGGNGTNGAY GARGARTCNGARYTNGGNAARATHYTNMGNAAR---MGNCARCARGCNATHCARGCNCAR GGNCCNCCNGCNGTNCARTCNGGN---------GTNGAY---GGN--------------- ------MGNCCNGTNCCNYTNCCNMGNAARYTNTCNACNATHCARGAYGARTCNGARGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNAARCCNCARCCNATHGCNCARCAYGTNATGCCNCCNAAYCCNCARCCNAARGGN TCNACNGTNAAYACNTTYACNCCNACNTCNGTNYTNGTNAARATGCAYTCNGAYAARGCN ATHGARAARGARAARCARGCNCARGARGTNGGNGARGGNTCNTCNATHGARTAYATGCCN TCNATGGARGARYTNAGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ACNACNTAYTTYGARAARTAYCCNGGNYTNATHCAY TTYATHTTYGTNGAYMGNMGNYTNCAYCARATGACNTCNCCNTCNYTNAAYATHTCNYTN AARGARGGNGARAARGTNAAYGCNAGYTCNTAYYTNAARGAYAAYATHTGGMGNATGTAY CARCAYATGATGCARAARYTNACNGARGGNTAYACNACNGTNATHYTNMGNGARGGNGAY TTYTAYTAYTCNTAYTTYYTNTGGTTYGARGAYAGYGCNGGNAAYCCNYTNCCNGTNCAR GARAGYTTYAARCCNTCNTAYAARYTNCCNTAYCCNGGNATHYTNTGYGGNTCNTTYTAY MGNGAYGTNYTNCARCARTGYTAYCCNCARATGATHACNAGYTCNGTNYTNTGYTTYGAR ATGTTYYTNATGCAYGTNGGNAGYGTNCAYCCNCARTAYATHGCNTCNCAYTGYAARAAR YTNGCNGTNGARYTNTGGGARATGTCNGGNGAYGCNTAYTCNACNYTNAAYYTNTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GCNACNAARATGAARMGN TCNGARMGNCAYATGATGMGNYTNAARAGYATHATHGCNAARGTNYTNGCNCARAARGGN GTNGARAARGGNCAYGCNATHTAYGARGCNTGYTCNAARAAYYTNYTNAAYGTNAGYATH ATHYTNYTNAARGCNYTNCCNAAYTCNCARAAYYTNACNGAYGARATGAARTCNGTNGTN TAYGARCARGTNCARCARATHATHAAYYTNGARAARMGNMGNTCNGGNATHGCNATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYCARAARCARAAYGCNTTYCAYAGYTCNTAYAARTCNATHTCNACN YTNATGATGCAYGTNTAYGARATHACNMGNCARYTNTCNYTNTGGGGNAAYAARTGYGAY YTNTCNATHTCNTCNGGNCARGARAAYAAYCAYACNGARAAYCCNYTNGARCARYTNGCN AGYYTNAARAAYAAYATHYTNGTNGAYGAYACNAAYAGYGTNYTNGARYTNYTNMGNAAR MGNCARAAYAAYYTNAAYGGNAARGGNGCNAARGTNTCNATHGTNYTNGAYAAYGCNGGN TAYGARTTYATHACNGAYYTNTGYYTNGCNGARTTYYTNTTYTCNTCNGGNYTNGTNTCN TCNGTNCARTTYCAYGGNAARGCNATGCCNTGGTTYGTNTCNGAYGTNACNGARMGNGAY GTNAARTGGTCNTTYGAYCARATGGGNGCNATGAAYCAYATHGCNATHAGYCARYTNAGY CARGCNTGGMGNGARMGNATGMGNGAYGGNACNATGACNTTYGARTAYGAYTCNTTYTGG ACNATGGCNCAYCCNTTYAGYCARATGGARTCNYTNCARCCNGARYTNTAYTTYAARYTN AGYCARGGNGAYYTNGTNATHTTYAARGGNGAYYTNAAYTAYMGNAARYTNGTNGGNGAY ATHAAYTGGGARACNACNGTNAAYTTYTCNCAYAGYYTNCARGGNTTYCARCCNACNGCN GTNTGYTCNYTNMGNACNYTNAARGCNGAYGTNGTNGTNGGNYTNAARGCNGGNCARGCN GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARTCNAAYTCNNNNNNN NNNMGNNNNNNNNNNNNNNNNNNNMGNNNNMGNAGYMGNGAYNNNAARTCN--------- ---MGNMGNNNNNNNAGYMGNGANMGNMGNAGYAARAGYMGNGARMGNMGNMGNMGNGAY GAYAARGARAARGGNMGNMGN---MGNAGYMGNAGYMGNGAYMGNMGNMGNAGYMGNAGY AARAGYMGNGAYMGNGAYMGNMGNMGNMGNAGYMGNTCNCCNGGNMGNMGNMGNAGYMGN AGYCCNATHMGN---GARMGNYTNCCNGARYTNACNGTNGARGARMGNGAYGTNMGNACN ATHTTYTGYATGCARYTNTCNGCNMGNATHMGNCCNMGNGAYYTNGARGARTTYTTYTCN TCNGTNGGNAARGTNMGNGAYGTNMGNYTNATHACNGAYAAYAARACNMGNMGNTCNAAR GGNATHTCNTAYGTNGARTTYGCNGAYCCNGARTCNGTNACNYTNGCNATGGGNYTNACN GGNCARAARYTNYTNGGNGTNCCNATHYTNGTNCARCCNTCNCARGCNGARAARAAYMGN GCNCARCCNGCNACN---GCNACNCARACNCARAARCARGCNACNGARGGNCCNYTNMGN YTNTAYGTNGGNTCNYTNCAYTTYAAYATHAAYGARGAYATGYTNMGNGGNATHTTYGAR CCNTTYGGNAARATHGTNGAYATHAARATHATGMGNGAYCAYGAYTCNCARMGNTCNYTN GGNTTYGGNTTYATHAGYTTYTCNAAYGCNGAYGAYGCNAARAARGCNYTNGAYCARYTN AAYGGNTTYGARYTNGCNGGNMGNCCNATGAARGTNGGNCAYGTNACNGARMGNTCNGGN GARGGNGTNCARGGN------GCNCARAAYGGNGTNGGNGGNCARYTNGAYACNGAYGAR ATGGAYMGNGCNGGNATHGAYYTNGGNGCNACNGGNMGNYTNCARYTNATGGCNAARYTN GCNGARGGNACNGGNTTYCARATHCCNCARTAYGCNGCNAGYGCNYTNAAYAAYATHTCN ------------ACNCCNGCNGCNGCNCCNGGNATHCCNGCNGCNGCNCCNCCNAAYAAY ATHGGN------------ATHCCNGCNATHCCNACNAGYGTNGCNGCNCARCCNCCNACN ------GTNACNAAYGCNCCNCCNATHGCNACNCARTGYTTYATGYTNTCNAAYATGTTY GAYCCNCCNACNGARGCNMGNYTNACNTGGGAYCARGARGTNMGNGAYGAYGTNATHGAY GARTGYAAYAARCAYGGNGGNGTNYTNCAYATHTAYGTNGAYAARAAYTCNCCNCARGGN AAYGTNTAYGTNAARTGYCCNAGYATHTCNGCNGCNGTNGCNTCNGTNAAYTCNYTNCAY GGNMGNTAYTTYGCNGGNMGNGTNATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYACNTTYTGGTAYYTNTTYYTNGARAARTTYCARCCNAGY CARAAYTAYCARGCNAARYTNTTYAAYMGNATHTCNCAYAAYTAYGTNAARYTNATGATG ATGACNGCNGAYCCNATHGCNAARGAYACNTTYTTYAARGAYTAYCCNAARYTNATGTCN CARGCNYTNTAYGCNTCNTTYTGYTTYTGYTTYCCNGAYTCNTAYMGNCARTTYGGNGAR AAYTTYAARGAYCARYTNYTNTAYYTNGTNTAYGGNTGGATGGCNGGNATHMGNCCNTCN CCNMGNAGYTGGYTNTCNTGGGAYATGTGYCAYYTNGARCCNGCNAAYYTNAARATGMGN GARGARATGATGCARAARAARAAYACNAARAARATGACNTCNTTYATHGAYTTYGAYTAY YTNGAYTCNYTNATHTCNACNAAYGCNAGYCARTAYGCNTCNACNATGTCNYTNGCNCAR TCNACNTCNAARGCNTCNACNGTNTCNAAYATHACN---GCN---MGNNNNCCNMGNATG CAYGCNMGNYTNAGY------------AARCCNYTNTTYMGNACNTCNTCNCCNAAYAAR ACNCAYTCNCCNACNTCNTCNCARGAYTCNAAYGTNATHGARGCNGTNGCNGAYGCNCAR AAYAGYCCNMGNGTNMGNGCNACNGGNAARGARCCNAARAARATGGAYACNYTNGCNCCN GGNAARGAYYTNAARMGNCARAGYGAYGCNYTNACNCCNATHMGNGARATGACNAGYGAR GAYGARGAYGARGAYTTYGGNAARAARTTYTCNCARGTNTCNATGAGYCARATHMGNGAR GCNMGNGTNAARGAYAARTAYGTNATGGARTCNCAYCCNATGGGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARTCNGARTTYATGMGNCCNMGNAARMGNMGNATHMGNGAYGARAGY GGNYTNTGGGTNGAYGARAARGARYTNGARGGNAARACNATHGAYCAYAAYGTNGCNGAR AARAARAARACNCARAGYMGNMGNATGAARCARATGAARCARATGTAYAAYCCNTTYAAR YTNGTNCCNTGYYTNTCNTTYACNGARGARAAYAARGARCCNTAYAARATHGARATHTTY AAYACNGCNYTNTCNATHATGGAYATHCAYTCNCAYATHTCNAARACNGARGTNATHGGN ATGYTNGGNGGNMGNTTYAAYCCNGARACNGARTGYYTNACNATH--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CCNCCNYTNMGNACNATH TCNGARCCNTGGGCNCAYCCNATHAAYCAYYTNTGGCARTCNAGYCAYCCNGAYGGNGAR GCNATHMGNMGNTTYAAYCARACNATGTCNTCNMGNMGNCCNCAYTGYACNGTNTGYTCN YTNTTYCARCARTTYGAYCCNGAYGTNGARYTNCARGAYMGNGTNAAYGAYGAYGTN--- ---------------ATHCCNTCNMGNTCNYTNCCNATGATHCCNGARTCNTCNTTYGCN GTNAGYGCNTCNAAYMGNACNCCNTTYTGYGAYTAYTCNCCNGTNGAYGARGAYGGNYTN AGYTCNYTNYTNGTNTGYTCNTCNTGYAGYGTNTGYGTNCAYGCNAGYTGYTAYGGNGAY YTNMGNGGNGCNMGNCCNYTNGAYTGGAARTGYGAYGCNTGYACNTCNGTNGARCARCAR CARAGYYTNTCNTGYGTNYTNTGYCAYYTNMGNGGNGGNGCNYTNAARCARACNTCNGAY GGNCAYTGGGCNCAYGTNTCNTGYACNYTNGCNATHGGNGAYGCNTCNTTYAARAAYGTN MGNYTNMGNGCNCCNATHAAYACNGCNAARATHCAYCARGARMGNTTYAARYTNAARTGY AGYYTNTGYAAY------------TCNGTNTCNCARCAYGCNCCNTGYATHCARTGYTCN CAYGGNMGNTGYACNACNGCNTTYCAYGTNTCNTGYGCNTTYATGGCNGGNATHMGNTTY GARATGTGYGAYTGGCCNGTNCCNATHTAYGTNTCNTGYMGNAARCAYATGTCNACNMGN AARAARGTNGARCARTCNMGNGAYATGCCNGAYTTYGAYGTNGCNAGYYTNGCNYTNGCN AARCAYAARAAYAARMGNTTYTAYTGGGCNAARGTNGTNCAYATHGARMGNMGNMGNYTN TAYGARGTNGAYTTYGAYGAYGGNTCNTTYAGYGARGAYYTNYTNCCNGARGAYATHGAR AGYMGNGAYTGYGTNMGNGAYGGNCCNCCNYTNAARGGNGAYCAYGTNTTYATHAARTGG GARGAYGGNTCNYTNTAYGGNGCNACNTTYMGNAARGTNAAYAAYMGNGAYYTNTAYACN GTNGARTTYGARGAYGGNTCNCARYTNCARGCNMGNMGNGARGARYTNTGGGGNGARATG GARGARATHCCNMGNCAYATHMGNAAYMGNATGTCNCAYGCNACNGARCARAARTTYGAY YTNTTYGAYGARGAR---GCNCARGAYGGNMGNMGNAAYAARAARAARGTNAAYTAYYTN AARATGYTNGAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGCCNTCNCCNGARGTNCARAARYTN YTNGAYMGNCAYAARTCNYTNGTNYTNGAYGARGGNACNCARAARGTNAARTGYAGYYTN ACNAAYCAYGARATGCCNGCNAARGTNGAYGCNATHGARACNTAYYTNAAYGGNAARAAR TAYAARMGNYTNGCNGARYTNGAYGCNYTNGTNTAYGARGAYCAYAARAARCAYATHGTN CCNAGYTTYAARAARAARAARGARAAYGARATGTTYTGYMGNYTNACNYTNMGNCAYYTN GARAARACNGCNAARGCNATHCARYTNCAYATHAAYGGNMGNAARTAYAARAAYGCNYTN GTNMGNTGGGAYGARTGYAARAARAAYGGNACNAARTTYGTNGCNCAYATHMGNMGNAAR CCNAARMGNCCNGAYGARTCNGAYGAYGARAGYGTNTCNGGNGAYGGNAGYGTNGTNGAR GAYGAYGAYTCNGAYAAYGARGAYAAYGAYGAYATGGAYGAYYTNTAYCCNGARGCNGAY TTYCARGAYGTNGAYATHCCNGAYGCNGAYATGGARGGNGAYGTNGARGARGAYGAY--- ------------------------------------------------------------ ---------------------------------------------ACNGGNGAYGARCCN GARAARACNCCNYTNCCNCCNGGNTCNYTNGGNYTNCCNATHATHGGNGARACNTTYCAR TTYYTNGTNCARGGNACNGCNTTYTAYGCNGAYAARYTNAARAARTAYGGNAGYATHTAY AARACNCAYGTNYTNGGNAGYCCNACNATHMGNGTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNYTNACNGCNTTYMGNAAYYTNCAYMGNGCNMGNAAR GARGTNTTYGCNGGNGAYGARMGNGCNYTNAAYGARGTNMGNCARMGNATHAAYTCNGGN TTYMGNGARAARYTNGARGARACNGAYGARTCNAARATHGAYGARTCNYTNATHYTNGCN AARGAYGTNGCNTAYYTNYTNMGNTCNACNGTNGTNCARYTNCARCARAAR------GAY GARGAYACNTTYGGNATHMGNATHACNAARAAYACNATHYTNCCNGARAAYAAYYTNTAY GAYCCNAAYAARGARATHCCNGCNATHMGNMGNAARAARAARTGYGCNGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TCNGAR GTNATGGCNGTNATHTTYAARYTNYTNGGNYTNYTNMGNATGYTNATHGARGGNCARGAR GCNGCNGCNATHAARYTNGGNCARGARMGNGCNTTYYTNGAYTGYYTNTCNGARTGGTGY ACNGTNGARGTNCAYGCNGGNGTNAARGGNGARGCNCCNMGNGTNATHGCNTCNYTNATH AARAAYAGYAARTCNYTNGCNGTNATHCARAAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNAARGAYAGY CAYMGNATGTTYYTNCARAGYTTYATGTCNMGNGGNGTNATGAAYACNAARGARGTNAAR GCNATHTAYGTNCAYAGYAARAAYMGNTAYTCNGARCARYTNGAYCCNGAR--------- ------AAYGTNACNGTNGARATHCCNAAYTTYGTNMGNACNATHAAYYTNGCNATHTGY CCNTTYAAYYTNGARATHMGNAARGGNATHCARGARCAYGAYGGNTCNAGYGTNTAYTGY YTNGTNAAYACNGTNGARAGYGCNATHTCNMGNYTNTCNTCNACNTAYACNGCNAAYGAR YTNGARYTNTTYAARMGNGTNATHGARTAYATHGTNGARTCNGAYGAYGGNYTNATHGGN TCNMGNACNGCNYTNAAYYTNACNGARAARYTNGARAARMGNATGGGNAARGARGARGCN CARAAYTTYTTYAAYAGYYTNGARMGNGARAARTGGATHGTNAARGGNGARGAYGGNAAR ATHTCNYTNTCNGTNMGNAGYYTNYTNGARYTNGAYCARTAYYTNCARGAYATGTAYCCN GCNYTNATHAARAARTGYAAYATGTGYACNGTNATHTGYGTNYTNGGNYTNTCNTGYCCN AGYTGYGGNATHAARATHCAYYTNAARTGYGCNAARAAYYTNTTYTCNMGNCARAAYGAR GAR---ACNTGYCCNGTNCCNAGYTGYMGNGCNGTNTGG--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNGTNATHAARGAYATHMGNGAYAGYATHAAYACNATHGAYYTNTCNMGN ATHAARGAYAARATGACNATHATGACNGTNAARTGGATGATGATGTCNGTNCARAAYACN AARAGYGTNCARMGNAGYATHTTYTCNTGGGTNACNTCNTCNTCNCAYGCNATHTTYCCN GARGAYAARYTNAARGAY---GCNTCNAAYCCNCARGAYGAYGAYATGGARATGAGYGGN MGNAAYAARAARGTNMGNGTNTGGGGNMGNYTNMGNCCNACNTCNAAYTTYGCNTAYGAR AAYATHGARTGYYTNCCNGAYAAYAARGGNATHAAYGTNCAYATGMGNMGNGAYCCNAAR AARGGNGTNGTNAAYAAYCARATHYTNGAYTGGTCNTTYAARYTNGAYGGNYTNTTYGGN AAYGCNGAYCARGARGTNGTNTAYAAYACNGTNACNTCNGAYATHGTNTCNGGNTCNYTN GAYGGNTAYAAYGGNACNYTNATGTGYTAYGGNCARACNGGNGCNGGNAARACNTTYACN ATGACNGGNGCNACNGARAGYTAYMGNCAYMGNGGNYTNATHCCNMGNGCNATHTCNCAR YTNTTYMGNCARATHGARGAYMGNYTNGARTAYAGYATHACNGTNMGNGTNTCNTAYATG GARATHTAYAAYGARCARATGTTYGAYYTNYTNGGNACNTTYCCNGARTCNAAYTGG--- ---AAYAGYAARGAYATHAAYTGYAGYCCNGAYCCNATGGTNATHTCNGARAAYCAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNGCNATGGAYTTYCCN AARAAYGARCCNGTNCCNCARGAYTCNCARAARTTYGARAARYTNYTNYTNAGYTGYGTN GGNGAYYTNGAYTGGATHCARGARGTNCARTAYTCN---AGYACNACN---AARAARYTN GTNMGNYTNAARGAYCAYATHCAYMGNAARGAYYTNGARGGNYTNAGYCCNCARCCNAGY GTNYTNGTNGARGCNGARCCNTCNGGNATHGTNAARGGNGTNGGNGTNACNYTNAARGGN TGYMGNGAYAAYGGNTGYGTNGAYGAYCARGGNAAYGARTAYGAYTTYGTNTCNMGNTAY TTYGCNCCNTGGAAYGGNATHCCNGARGAYCCNGTNACNGGNTCNTGGCAYACNGTNYTN GGNGGNTAYTGGGCNAARCARYTNGGNAARACNCAYYTNTAYGCNMGNCARTGYTCNCAR MGNGGNGGNGAYYTNYTNGTNGARGTNGAR---TCNMGNGTNACNYTNAAYGGNCARACN GTNATHAAYYTNAARGGNACNTTYCARYTNATGGGNAAYAAYCCNAARAARCARTCNAAR TCNTTYAARGTNYTNCARTGGATGACNGARACNGARAARGARGARGARCARGAYGARGAR ---------GCNGGNCCNGAYYTNMGNCCNAARCCNMGNAARCAYAARGAYCCNGAYYTN MGNCAYAAYGCNGAYGAYGAYGARATGMGNTTYACNGGNYTNCAYAAYAARACNGCNATH CCNTCNAARGCNTTYGGNMGNATHAARMGNTCNACNTCNGTNGARGARAAYGGN------ ---AAYGGNCARAAYAAYGTNTAYGTNGGNGAYGGNACNGARGCNGTNGGNGAYTAYAAY GARGARTCNATHMGNTAYGTNGGNAARAGYATHCCNTCNCCNGCNTTYMGNGTNYTNCAR ACNTGGGCNGARAAYGAYCCNGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TAYYTNTCNACNYTNCAR CCNCCNYTNTCNTCNTAYGARAAYTTYYTNGARYTNCAYGAYCAYYTNGARGCNGTNCAY GARAAYGAYATHATGGARATHACNAARTGYYTNGGNAARGGNGCNTAYGCNCARGTNTTY AARATGTAYAARGAYTTYTTYGCNATGAARGTNCARAGYCCNCCNTGYCAYTGGGARTTY TAYATGGCNCAYGARATGCARCAYMGNYTNACNGCNYTNCARGCNCCNATGGAYGTNMGN CCNTCNYTNATGAAYGTNGAYTAYGGNTAYTTYAAYGAYAAYGTNAGYATHYTNGTNATG AARYTNATGGARCAYGGNTCNYTNYTNAAYYTNGTNAAYATGTAYAARGCNGAYCCNAAY YTNATGGCNCARGTNGARCCNTTYGTNTGYYTNGCNACNGTNGARYTNYTNCAYYTNTTY GARCARYTNCAYAARTGYGAYATHATHCAYGGNGAYGTNAARCCNGAYAAYTTYYTNYTN ATGGAYYTNTCNYTNGTNCCNGARAGYAARAAYGCNAGYGARGTNTTYGGNTCNCAYYTN MGNACNTTYTGYYTNACNGAYTTYGGNCARAGYATHGAYATGCAYATGTTYCCNAARAGY ACNACNTTYMGNACNAARGTNACNGCNAGYGGNTTYGARTGYATHGARATGMGNACNGAY MGNCCNTGGACNTAYCARACNGAYYTNTTYGGNYTNGCNGGNACNATHCAYGTNYTNYTN TTYGGNTCNTAYATGAARGTNTTYGTNGARCARGGNGTNTGGAARACNACNGGNAAYTTY GTNMGNAARTGGAAYGTNCCNYTNTGGAARMGNYTNTTYCAYGARYTNYTNAAYATHCCN TCNTGYGAYTGYYTNCCNAAYYTNTCNTCNYTNMGNGCNGARTTYGARGAYTAYTTYTGY TCNAARYTNATHGARCCNTAYAAYGARTGGATHAGYAARGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARTTYGGNAGYGTNGCNYTNCARGARAARYTNAAYATGGAYTCNTTYGCNAARYTNTAY GARTAYTAYTCNGCNTAYAAYGCNCAYTTYGARGAYCCNTCNGAYAARGTNCARGGNGTN MGNTCNYTNAGYCAYATGATHAARATGYTNCARAAYAAYGTNATGACNAARAARAGYAAR AAYGTNGAYYTNYTNCAYACNGCNGCNGARGTNACNMGNACNATGMGNGGNYTNMGNGTN ACNTTYTGYAARAGYGGNAARGAYMGNACN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNAARTCNGARCAYGTNGGNGTNGARGAR ATHGCNMGNGCNAARTGGATHTGYYTNAAYAARATHTCNTAYAARGAYCCNCARGGNAAY ACNMGNGTNTGGGARGGNGTNTCNMGNACNACNAARAAYAGYGGNGARGCNGAYGCNGTN GGNATGATHTGYATGTTYCAYGAYCCNATHACNGAYYTNCARAGYATHATHATGATHMGN CARTAYMGNCCNCCNATGGARACNTAYACNATHGARTTYCCNGCNGGNYTNATHGAYGCN GGNGARACNGCNAGYCARTCNGCNATHMGNGARATGAARGARGARACNGGNTAYGAYGTN ACNGTNYTNGAYGTNTCNCCNGGNACNTCNYTNGAYCCNGGNGTNGGNAAYACNACNYTN AARYTNGTNACNTGYAARGTNGAYACNAGYAARYTNAGYAARAAYGARMGNCCNAARCCN ACNGGNGGNGAYGCNGAYGARTTYATHCARGTNGTNGTNCARCCNYTNAARACNYTNATG GARAARYTNAARGARTTYGCNGCNCARGGNGAYTGYGTNGAYTCNMGNGTNTAYGCNTGG GCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MGNGCNAGYTGY MGNTAYTTYTAYMGNAAYCARMGNAGYAAYCAYACNCARTGGGARTAYCCNGARGCNGAR GARGAYAARGARGTNMGNCAYAARAARMGNAGYAARGARAARGARGARMGNGAYGARAAY AARTCNMGNGGNAAYAGY---------------TCNAGYMGNAGYAGYMGNCAYMGNAGY AARAARGGNCARGARAARGAYMGN------------------GGNAARMGNGAYMGNCAY AGY---AGYAGYCAYCAYCAYMGNAARAARAARMGNMGNMGNMGNGAYCAYAGYAGYAGY AGYAGYAGYAAYAGYGAYAAYGARAGYACNCARTCNMGNCAYMGNCAYMGNAGYAARMGN AARAARMGNGTNMGNTCNGAYAARTCNCARAGYGTNGARYTNYTNGAYGGNACNGARCAY GCNCAYGTNATHGAYGAYAGYCCNCCNCCN---------------------TCNATHYTN CCNGTNGAYTCNCARCCNTCNGCNYTNGAYAGYGARGAYMGNTCNAARCCNACNGCNTCN YTNYTNGTNGCNGAYTAYGGNTCNGARGARCARGAYGCNGAYAARGARAAYCARGGNCAR AGYGTNGARACNGARGARCARGARYTNGAYAAYGAYGGNGGNGTNGGNGCNGGNATHGAY GGNGARGARATGCCNACNGAYGGNGCNGCNYTNCARCARGCNGARGARATGGARGARGAR GTNAAYTCNGCNGTNATHGTNAARCCNCCNCARATHATHGTNCCNCCNTAYGTNGCNGCN ATGAAYCARCCNCARATGTAYTCNACNCCNTCNYTN---TAYACNTCNGCNGCNCCNGCN GGNCARGAYGGNGARGGNGARACN---ACNACNACNCARCARACNTCNGARGARGTNGAR AARGGNAGYAARAARAARAARAARGAYAARTCNGGNAARGARAARTCNYTNACNGCNAAY TCNAGYATHATGATGAARAARAARMGNGTNTCNTCNATGGTNCARAARTGGCARCARGTN AARAARGARGTNGARAARGARGAYMGNGCNAARGARYTNMGNCARGCNGCNATHMGNGAR AARATHAAYCARYTNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AAYCARTTYYTNCCNGCNGARCAYCARATGCAR TAYATHGGNTTYGAYATGGCNMGNGTNAAYAARMGNAARGAYGCNGAYGTNATGYTNMGN YTNAAYMGNATHGCNMGNTAYTGYYTNAARCARACNGGNTTYTAYYTNMGNGTNCARCAR CCNCARGCNCARTAYYTNCARAARGAYGCNGARYTNCARAGYYTNAARGGNGTNTGGGGN GCNAAYGGNATGAGYCARACNGGNGCNGTNMGNACNAAYTGYGTNGAYTGYYTNGAYMGN ACNAAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARGARAARYTNAARGAR---GARGARMGNATGCARCARGTNATGATHGAR AGYAARCARGARGARYTNMGNAARCARCARAGYGARYTNGARMGNCARMGNGARCARGTN MGNMGNGARAARGARGARYTNGARMGNGARMGN---YTNAARYTNGARGARGTNMGNMGN GARCARGARMGNYTNGCNCARYTNGARAAYGARMGN---------CARAARAARGARMGN ATH---------------------------------GARYTNGAYYTNMGNMGNCARGAR GARAARMGNMGNCARGARGARGARAARAARMGNGAYCARGARYTNAARAARCARGARGAR AARAARMGNAARGARAARGARAARGTNGARGARCARAARMGNCARGGNGARGCNMGNMGN AAYAARGARATHGARGARYTNMGNCARMGNCARGARATGGARCARGTNATGGARGCNMGN MGNAARGARGARATGCARMGNCARATGGARYTNCARCARATHCARGARGARGARGARMGN ATGAAR---------MGNGARGTNGTNGARAARGARAARCARCARGTNYTNAARAARCAR CARATGGARYTNCARMGNCARCARGARTCNYTNMGNAARYTNCARCARGCNCARMGNGAR CARYTNGCNAAYATHCARYTNCCNGCNTCNAGYAAYTGG---GCNAARCARGGNTCNCAY GGNGGNYTNGGNAAYTCNAARTCNYTNACNGARATHCARGARGARGARTCNMGNAARGAR MGNGARMGNCARAARGARCARCARGCNCARAARGARMGNATHCARGARCARGCNGCNATH TTYAAYCARCAYCARAGYCARAARTCNTGGGCNTCNCAYGCNTCNAARGGNGCNACNMGN GGNYTNTCNYTNYTNGAYATHCARCARCARGARAARGARAAYGCNAARAARACNGAYAAR GGNAARGGNCAR---AAYCAYCARGCNAARCCNAGYYTNGGNAGYGGNAGYACNTGGACN GGNACNAAYGGNACNAAYTCNATGTGG--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MGNGCNAAY TAYTTYTAYTGYGTNMGNGTNACNGAYCCNGARATHCAYAARAAYATHGARAAYGCNYTN AAYTGGATHGTNGAYAARGARCCNCARTTYGARGAYTAYTGYTAYACNAARGARATGYTN CAYGTNACNYTNGCNGARGTNTCNYTNCARAGYGAYGARGAYATHTCNYTNGCNTCNAAR GTNYTNGARGAYTGYCARTCNGGNYTNMGNGGNYTNACNCCNACNGAYCCNATHTCNATH AARGGNATHTCNGAYTTYCAYGARAARGTNATGATHGGNAARGTNGARCAYGGNCARGAR TTYYTNACNTTYGCNGAYTTYYTNMGNTCNAARGCNAARGARGCNGGNGTNAAYGTNGTN GARAAYCAYAGYTTYAAYCCNCAYATGACNATHYTNAARGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GCNACNGARYTNTGY AAYAARGCNAAYGARGARTAYGTNGARGARAAYTAYCARAARGCNGTNGAYYTNTAYACN GARGCNYTNGCNYTNGARGAYAARMGNGAYGAYATHTAYTGYTTYMGNGCNCARGCNCAY YTNTCNYTNGGNAAYACNTCNGCNGCNGTNAARGAYTGYGAYGARGCNATHAARYTNAAY AARAAYAAYCARAARGCNTAYGTNAARAARGGNTCNATHYTNYTNAARYTNGAYGAYGTN YTNCARGCNCARAAYGTNTTYAARGARGGNCARGARCARTGY---GGNGAYAARGGNTTY GAYGAYTGGYTNGGNAARGTNGARAGYMGNATG---------------------AARGAR YTNGGNATHGGNCARTCNACNCARGCN------------------CCNACNYTNAARTAY AAYTGGTAYCARACNCAYACNCAYGTNACNGTNACNGTNYTNGTNAARAAYGTNAARAAR GARGARYTNACNYTNGAYGTNGARGGNMGNTCNYTNAARYTNACNATHAARMGNGGNGAY CARGAYAGY---GAYYTNGAYATHACNYTNGCNCAYCCNATHGCNCARGARCARACNCAR TCNAARYTNTTYTCNACNAARATHGARATHAARYTNAARAARCARGARGGNATHCARTGG GTNAARYTNGARGGNTCNCCNGAYGTNGTNGARAARAGYGTNYTNCCNCCNTGYGCNGCN CCN---GARGAYGCNGARGCNCCNMGNTAYCCNAGYTCNTCNCAYTAYACNMGNGAYTGG GAYAARYTNGCNGCNGARGTNACNGARGARGARAARAAYGARAARYTNGARGGNGAYGCN GCNYTNAAYCARTTYTTYCARAARATHTAYGCNGAYGCNTCNGAYGAYACNAARAARGCN ATGATGAARTCNTTYTCNGARTCNGGNGGNACNGTNYTNAGYACNAAYTGGTCNGARGTN GGNACNAARAARGTNGARGTNAARCCNCCNGAYGGNATGGARTAYAARGARTGGGAR--- ---AARATGCCNAARMGNAARTCNGARGARGCNGTNGCNCCNGARTCNCCNAARAARGCN AARGCNGARCCNGCNGCN------------------AARAARTCNGCNACNGGNAAR--- ---------------MGNGGNMGNCCNCCNYTNTCNGCNGARGARAARGCNAARMGNGCN GCNAARAARGCNCCNCCNTCNGGNMGNGGNMGNGGNMGNCCNAARGGNTCNACNAARTCN AARAARGGNAARAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------MGNACNCCNACNMGNATGCARCCNATHGCNCCNAARACNTCNCCN TGYCCNAARTCNGTNCCNTAYGTNCCNYTNCCNMGNATHAGYCCNAARMGNAARGARYTN AAYMGNCARGTNMGNAAYATHYTNCCNAARTCNTTYGTNTTYGARACNAARAAYCCNTCN CCNACNAARACNACNGCNYTNAGYYTNAARMGNAARGCNACNYTNYTNTGYCARAARAGY CCNGTNAARATHYTNCCNMGNCCNCCNTCNGCNCCNGCN------AGYGAYAARGARTCN GARACNGGNAAYCARYTNATHATGACNACN---------MGNCCNMGNTCN--------- ---------------------CARMGNMGNAARTTYAARACNAARAARACNGARGARTCN AARMGNGTNAARAARACNGARGARGAYTCNGARAGYGCNAARGARACNGARAGYGARGCN AGYGARGTNGARGARTCNGGNYTNTCNCARGARGARGAYGAY------GAYCARYTNAAR YTNAAYGAYYTNATGGCNGCNAGYACNACNATHMGNTTYGGNTCNAARCARMGNGGNAAR GTNGAYGARGAYGTNAARACNAARGCNGARMGNAARAARGCNATGTCNYTNTCNYTNYTN CARCCNGAYYTNGTNCARGGNGAYCCNAARAARGAYGAYMGNGAYACNGCNTTYGCNAAR CARTAYTTYAAYCARGTNAARGARACNYTNTCNTCNGARCCNGAYMGNTTYTAYAARTTY YTNTCNYTNYTNAARGAYYTNAAYAARGAYCAYACNAGYCCNGTNGARYTNTAYYTNGAY ATGGTNTCNYTNYTNTCNGAYCAYMGNCARYTNGTNGARGAYTTYTCNGGNTTYYTNYTN TCNTTYCARGCNGTNGARTGYAARTGYTTYTCNACNAAYTTYCARTAYGCNCARATHMGN CARTTYYTNMGNCARGTNGARATHCAYTGYGGNTCNTCNGCNAAY---ACNTAYCAYAAR ATHYTNMGNGCNATGGCNACNTGGTCNAAYGTNTGYCARGARGGNAARYTNGAYGGNAGY YTNMGNGARAARATGYTNGGNATHYTNAARAAYGTNCCNGGNGTNYTNGAYAAYYTNATH GGNTAYTTYYTNGAYGGNACNGTNTCNGAYTGYCAYTCNATGGAYTTYGARGAYGTNTGY YTNGAYGAYGARATGGAYGGNGGN---------GAYGARTTYGARAAYGTNATHYTNCCN GAYGARMGNGARGAYTAYAAYACNAARACNTGYACNTGYCARTGYCAY---AGYAAYGCN CARGAYGARMGNTTYCAYMGNMGNATHAARCAYTGYATHTCNTGYAGYYTNCARATHTAY GARGGNCARCCNGTNYTNAARATGTCNMGNAGYGARTTYMGNCCNATGTCNATHGTNTAY CCNTCNGARGARGTNGARGARAARGARMGNYTNGCNAARGTNAARAARGARGCNGCNCAR ATHGCNYTNGCNAARGCNAARGTNCARAARGCNGARAARAARAARGARYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARAGYTCNYTNATHATHCARTGY YTNTCNGCNATHCCNGARCCNAARATHACNGAYGTNGARGCNMGNAGYGCNATGATHAAR YTNTCNGCNCCNGARTGYGGNGAYACNATGGAYYTNTAYCCNTCNGAYYTNAARTAYGAR YTNTTYYTNTCNGAYAGYGGNMGNGAYGAYAARTAYGAYTCNGTNTTY------------ ---------CARGARATGGCNTCNATHGARMGNATGCCNACNCARGAYMGNYTNAARCAY GCNMGNAARMGNMGNYTNCARCARYTNAARAARTGGAAYCARTAYGARAARCARYTNGAR AARGARAGYAGYAARAARMGNAARAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AGYATGATGACNTCNTCNYTN ACNACNCCNYTNCCNCCNAARMGNYTNTTYCAYYTNGAYGAYACNAARGAYTCNGTNGAY TCNGARACNAARATGTCNGCNACNACNGAYACNGARGAYATHMGNYTNMGNAAYACNATH AGYGTNGAYCARGARAAYACNAARGAYTCNGTNGCNTCNGAYTCNGTNGCNGARGGNCCN ACNCCNTCNAAR---MGNGTNAARGGNTAYMGNGARGGNYTNGGNGAYGTNATHMGNGAY TTYAARGGNGTNTTYACNGCNGARAARYTNTTYGARTAYCARTGGCCNCARGAYGGNGGN GARTGGCAYATHYTNCARGARCAYGTNAGYGAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNCCNGARTGYYTNATHYTNTCNMGNATGYTNGTN GGNYTNCAYTCNGGNTGGAAYATHGCNGTNTGYCCNATGTAYYTNACNGARATHTCNCCN AARMGNATHMGNGGNGCNATHGGNACNTGYCAYCARYTNTTYATHACNGTNGGNATHYTN TTYTCNCARATHATGGGNYTNCCNGAYYTNYTNGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TGYMGNTGYGGNCARGGNGTNGCNGTNYTNACNGCNGTNCAYYTNGARTTY CCNGCNYTNAGYYTNAAYAAYGARGAYAARTAYYTNAARAARYTNYTNCCNCAYTTYGTN MGNGCNGARGARAARMGNMGNATHGTNTTYMGNGAYATGYTNAGYCAYYTNGGNATH--- ------ATGGCNAARMGNGGNCCNCARTCNGARYTNACNGAYMGNAAYTGGGAYGAYGAR GAYGARCCNGARGARGCNGGNGTNTTYATGCARGCNTCNAARGARACNYTNCARCARMGN GTNATHAARAARGCNAARMGNMGNGGNGARGGNTCNACNGGNGGNAARACNGGNGCNTTY GGNGGNTTYGGNGGNYTNYTNCARMGNCCNTCNYTNGCNCARAGYAAYACNGAYAARGCN CCNAGYATHAARGCNCCNTCNGCNAAYGAYTTYAARCCNAAYTTYACNGGNGGNGCNACN TCNTCNGTNGAYAAYATHGARACNTCNAARGGNGAR---------TCNAARGARAAYTCN TCNTAYYTNCAYGGNYTNAARTCNYTNAAYGARAGYGTNYTNGCNTGGATHAARCARCAY GTNGAYAARAAYCCNTAYATHATHYTNACNCCNATHTTYAARGAYTAYGARAARTAYYTN GCNACNYTNGARACNAARAARTCNCCNTTYTCNGCNTCNACNACNACNACNGCNAARCAR GGNGGNGCNAGYGARATGAARACNACNTTYACNTCNCCNGTNTCNCCNAARAARYTNYTN GAYGAYACNGAYCCNAARAARGAYGGNAARGARGARGTNAAR---------GARTCNTCN AARTCNTCNGGNTTYTCNTTYGGNTCNGTNACNTCN------AAYGGNGARGGNTTYAAR TTYGCNTCNGCNACNACNGAYTCNGGNTTYTCNTTYGGNAARAGY---------ACNACN GCNTCNTCNGGNTTYTCNTTYGCNCARAGYAGYTCNACNCCNGCNCARACNGCNACNACN ACNGCNGCNTCNTCNGGNTTYACNTTYGGNAGYAGYGGNAGYACN---TCNACNTCNACN ------------------GGNTCNGGNTTYTCNTTYGGNACNYTNGCNGCNAARACNATG GCNTCNCARGTNTCNGARGGNGCNTCNGGNAGY------GCNGCNGAYGAYGAYGARTAY GTNCCNCCNAARCCNGARGTNAARGARATHAARGARGARGGNTCNYTNTAYAGYAARMGN TGYAARYTNTTYTAYCARAARGARGGNCARTGGAARGARMGNGGNGTNGGNAAYATHCAY YTNAARCCNYTNGGNGARTCNAARACNCARATHYTNYTNMGNGCNGAYACNAAYYTNGGN AAYATHYTNYTNAAYATHATGYTNACNTCNGGNYTNCCNGTNTCNMGNCARGGNAARAAY AAYATHYTNYTNGTNTGYGTNCCNAAYCCNCCNYTN---AARGARGGNCARGARGARGAY CARACN------CCNATHCCNATGYTNATHMGNGTNAARACNGGNGARGARGCNGAYGAR ATGYTNGCNAARYTNGAYGARMGNAARGCNYTNYTNAARTCNTCNGAYTGGTTYGCNCAY GGNAAYACNGCNAAYCCNCARCCNGARGCNMGNYTNMGNTCNGAYGCNGCNMGNGAYAAY GCNYTNAARAAYMGNGGNTCNGTNGGNGARAGYATGGGNGGNTAYGCNAAYCCNGCNGTN GARMGNACNYTNCAYCCNMGNGGNGTNMGNCCNGARGCNCARGGNGCNGCNTCNGAYAAY AARGGNGGNAAYATGAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNATGAARCARATHGCNTTYMGNACNGTNGGN YTNYTNTCNACNGTNAGYGTNTGGTCNATHATHCARCCNMGNGTNGARGTNMGNACNYTN CAYGAYGCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYGAYGAYGTNYTNYTNGGNTCNCARGGNTCNTGYTGYAGYGAY GGNCCNGAYGTNCCNGARCARAGYATHYTNGARYTNTGGCCNGARGARGARGARATGGAR GCNGCNTGYACNCARYTNACNCARACNAGYATGGARGCNYTNAGYGAYAARYTNATGAAY TTYYTNMGNGAYAAYCCNACNATHTAYGARAARATHYTNATGTAYGARGCNYTNGARYTN GAYGTNYTNAARAARYTNATHTCNGAYGCNGGNATHMGNATHGGNATHGCNMGNYTNCAR GAYTTYYTNGAYGARMGNTGYATHACNTTYTCNATGAARAAYATGAGYAAYMGNAAYAAY AARCARGTNCARMGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AARATHGGNATGYTNAAYGAR AAYATHTCNTGYYTNGARAARAARGTNTCNGTNYTNCARTCNGARMGNGARATGTAYTCN GAYCARGTNAARAARGCNTTYATGMGNGGNATGTGYGCNYTNAAYATGGARACNATGTCN GTNTTYGGNGGNGAYAGYGGNGGNYTNGCNGAYATHYTNATHGARGARGTNTCNTCNTCN ---------------------------------------------GAYACNYTNGCNCAY AAYYTNGAYTCNGCNATHCCNTCNAARGAYAGYCCNTCNGGNGARTTYCARACN------ ---------------------------------------AGYCARTCNGCNTCNYTNTCN ACNGGNTCNTCNTCNTCNAAYCARYTNTGYGGNTCNCCNAAYMGNGARAAYCAYCARCAR YTNCAYAGYAARGCNGTNTGYGGNTCNAARTCNACNYTNGCNGCNAARMGNAARCCNMGN TCNGTNGTNGCNACNTCNCARGTNYTNGCNCCNCCNATGGCNTCNGTNGTNGTNGARMGN CAYCARCCNGTNACNAARCARACNGTNGGNAARGCNACNGCNYTNMGNTAYCCNAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GAYGARAGYTAYMGNAARATHGAYGCNGAR TTYGCNMGNGCNATGAAYGAYGGNGGNYTNAARTCN---TCNGTNCARTAYCARATHCCN GTNCARGCNGCNACNGCNCARTAYACNGCNGCNCCNGCNAAYATGGCNAGYGGNGGNTCN GTNATHGTNYTNCARCCNTCNGGNGCNGTNGCNAAYACNGTNACNMGNACNCARGCN--- ---ATHAGYCAYGTNAGYGCNTCNCCNGGNATGACNACNAARATHACNGTNAAYCCNACN AAYGCNTCNAAYATHGCNCAYCCNGTNGCNYTNCAYATGGCNGGNGAYATHCCNMGNGTN ATHGCNGCNGCNTCNACNTCNACNCCNCARACN---------TCNGCNGCNAARAARCCN GGNYTNAARGTNGTNATHCCNGAYMGNGGNCCNGCNGTNTCNCARGGNAARYTNCAR--- GGNACNGCNYTNGAYACNCCNAGYGTNTCNATHGCNACNCCNAAYAGYCARAAYATGGCN CARGGNACNATHCARGCNATHYTNCARTCNGGNGAYYTNYTNAAYAGYGCNGAYATHACN GGNYTNTCNCCNYTNGTNTAYCARYTNACNAAYCARGGNTCNGGNCCNGGNCCNYTNACN GCNGCNYTNCARGCNTCNGGNGTNTTYACNCCNGGNGGNTCNYTNTCNATGTCNACNACN CCNATHATHACNYTNCCNCCN------GCNCARAARTCNGARYTNGTNAARCARGAR--- CCNGGNTCNCCNCAYAARCAYGAY---YTNTCNGAYMGNACNTCNGGNACNCCNCCN--- ------------GGNGARCCNCCNGARAARMGNTCNMGNTTYGAYACNGAY--------- ------TGYTAYAARTGYGGNGGNMGNGGNCAYTTYGCNMGNGAYTGYATGCAYGGNCCN GGNGGNCCNACNCARMGNTCNGGNGGNTTYCARGGNCCN------------------TCN TTYCARGGNCAYAARTGYTAYAARTGYAGYMGNACNGGNCAYTTYGCNMGNGAYTGYACN CARGAYCARGARMGNTGYTAYAARTGYAAYGGNYTNGGNCAYATHGCNAARGAYTGYGAR AARGCNATHTCN---CCNGGNGCNTGYTAYAAYTGYGGNAGYGAYCARCAYYTNCARMGN GARTGYCCNCARGCNATHGTNAARACNTGYTTYMGNTGYAAYCARGCNGGNCAYYTNGCN MGNGAYTGYCCNAGYGAYCAYGGN------CCNGGNACN------------GAYGAYMGN AARTGYTAYTCNTGYGGNGGNGTNGGNCAYATGGCNAARGARTGYCCN------------ TCNGTNMGNAARGARTGYTAYMGNTGYAAYCARAGYGGNCAYATHCARAARGAYTGYCCN AAYTCNCCNCARACNTCNGCNCARTGYTAYAAYTGYAAYGARAGYGGNCAYATGGCNMGN GAYTGYACNGCNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARMGNYTNGGNGARGGNGARATHGAYYTNYTNGARGTNMGNMGNGARATH GARTGYCARATHGCNGARTTYGTNAARYTNGTNGGNAARAARCCNTCNTAYGTNGAYGGN CAYCARCAYATHCAYGTNCAYCCNGCNGTNGCNGAYATHTTYGCNTCNACNYTNCAYGAY AAYAGYATHCARGTNACNMGNYTNCCNGTNGARATHTCNATGGCNAGYAARGARTGGGTN AARGCNGGNGTNMGNCARTTYTAYGARGARGTNATGAAYGAYGCNGARAAYTGYAARACN GTNTTYGAYTCNTAYGGNGTNMGNTAYAGYGAYACNTTYGTNGGNYTNTCNACNATGGGN GCNGAYATGACNTTYGCNMGNYTNCARTCNAGYATHYTNGARAGYTTYAARGAYGCNGAR AARYTNCAYMGNAAYAARYTNAARTCNTAYGTNATHTGYGARYTNATGACNCAYCCNGGN TAYGCNACNAAYAARGAYGGNGGNGGNTTYGAYGGNCARTCNGAYGARTTYGGNTGYTCN CARGAYMGNGARCAYGARATHGGNGTNYTNAGYTCNAARGARATGTTYGAYTTYTAYGAR GARAAYAAYATHCARYTNGTNTCNCAYGARATHTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARGAYGCNGCNGCNMGN GARGARMGNGARAARMGNMGNMGNAARGTNYTNGGNGAYCARATGAAYGCNCAYCARGCN CARGARGARGCNMGNMGNGARGARATGATGGTNAAYMGNYTNATGMGNCARTCNCARCAR GARMGNMGNATHGCNGTNCARYTNYTNCARGCNMGNCAYGARAARGARGTNATHMGNCAR AAYMGNATHTCNMGNGARAARCARTAYCARGARMGNMGNYTNAARGAYTTYGARGAYGCN YTNGAYYTNGARGCNGARATGGCNGCNYTNCAYAARATGGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNGAYATHTTYCARTCNTTYGCNGARTGYGAR AAYGCNYTNAARAARTAYGGNGAYGARCAYTTYACNGTNTTYGTNAARGCNAAYTGYAGY MGNYTNAGYGCNGAYCAYCCNGAYTGYTGYMGNYTNCARTAYAAYTTYATGAARTAYGAR TGYAARCARGGNTCNAARMGNAAR---ACNAARAGYCARGGNACNMGNCCNAAYCARMGN ACNGTNAARCARGGNTGYGARGCNTTYATHMGNGTNGTNAARGAYAARGAYGGNGARMGN ACNTTYYTNAARATHAARTCNYTNAAYYTNTCNCAYAAYAAYCAYCCNGTNGAYAARAAR ACNGTNTCNYTNTAYCCNGARAAYMGNAARGCNAAYGTNACNGARACNGTNAARGCNYTN GTNGCNGCNAARACNCCNAARAARGARYTNCARCARTAYATHGCNGARAGYCARGGNGTN ACNATGYTNCCNATGGAYATHTAYAAYYTNACNMGNMGNYTN------------GTNGGN MGNYTNMGNTGYTTYGCNGTNGGNGTNTTYGGNAARACNGGNMGNTCNTAYYTNCAYACN ACNCARMGNAARTCNGGNGARGCNYTNTAYMGNGTNTAYGAR------TAY------AAR GARCCNAARTAYATHCAYCAYGCNGGNACNGCNTTYAGYGCNTTYATGTGGTAYTGGATH YTNTAYCAYTGYTAYTTYGARTTYGARCAYYTNATG------------------NNNGCN ATGTGYATHYTNATHCAR------------GARGCN------ATHTTYYTNAAYAARYTN GGNGARATHCCNGTNYTNAAYGAYGGNTGGTCNACNGCNGCNGGNTAYTAYTCNMGNGTN AARGAYTAYAAYGCNYTNATGMGNYTNACNYTNTCNATGGCNGARTCNAGYGTNAARGTN GCNGGNCARATHTCNGCNCCNGTNYTNAAYCAYTAYCARCCNCARATHAAYAAYATHAAY GAYTTYGCNTGYAARAARYTNGAYGARYTNGARAAYTCNTAYCCNGCNATHAARCARCCN ACNGARCARYTNAARGARACNTGYGCNGGNTAYGTNGARCCNGTNATGGTNMGNGTNAAR CCNGTNATHTCNCARGTNAAYGGNATHATHGAYAAYGGNAARCARAARATHGTNAAYATH AARACNGCNAGYACNAAYATGGTNGARGGNGCNAARACNMGNGGNGTNGGNACNGTNACN CAYGTNTTYAAYTCNACNTTYGARAGYGCNCCNGGNMGNTTYGTNACNMGNACNGCNGAY GGNGCNYTNAAYATHGCNGARGGNYTNGTNGAYMGNTAYYTNCCN---------GARGAR GARAARGARGTNGARGAYAARAGYAAYTCNGAYGARGCNGAYGGNGAYTCNAGYGAYGAY AGYATHGAYCAYGARATHGARAARATGCARGARATGAAYCCNACNCCNAARMGNGTNATH GTNCAYGCNGGNTGYATHACNGCNAARATHMGNAARMGNATGTTYMGNYTNGCNGTNAAR GAYYTNACNTAYGCNAARGCNMGNACNGTNTCNGCNYTNAGYCAYATGCARAGYACNGTN AAYYTNATHGAYTAYGCNAARACNAAYGTNGCNGCNGCNAARGAYAARGTNGAYGAYYTN TGGACNGARATHGTNAARGARAAYGGNACNGARGARGARAAR------------ACNGTN TTYGTNGGNACNATHGARGAYMGNATHGTNGCNYTNGGNMGNYTNGTNGCNMGNCARGTN AARTCNGGNGTNACNGCNYTNGARAARGCNTCNTCNGARYTNGGNCARTTYGGNAARAAY CCNATHTCNAARTCNAARGARTAYAARCAYYTNATHGARACNTTYYTNCARACNGARTCN ATHCARAAYTTYTCNTCNCARAGYYTNGCNAARGCNMGNGCNTCNYTNACNTAYATHCAR AGYCARYTNCAYAGYTTYGCNAGYAGYTCNTCNTCNYTNAAYTGGGTNGCNATGGAYATH GAYATGGARAAYATHCCNYTNGAYGARAGYGAYGTN------------------------ ------------------------------------------------------------ ------------------------------------------YTNCARTCNATGTTYAAR AAYTTYAARGAYATHAAYTCNGAYGAYGARYTNMGNTCNAAYGARGCNYTNGARTAYCAY GCNTCNATGGTNATGACNACNYTNGAYGAYGCNATHACNCAYATHGAYAAYTAYGARTTY GTNAARAAYCAYYTNGGNCARACNGGNGCNTCNCAYAARMGNTTYCARGGNTTYGARCCN AARACNTTYYTNAAYATHAARCARCCNTTYYTNGAYGCNGTNAARGTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNATHMGNACNATHGGNMGNTGYAARTTYGAYGAYMGN GARGARGAYATHGAYGCNYTNATHGARMGNGGNGCNGAYATHAAYMGNYTNCAYGGNACN GTNYTNCCNYTNCARTAYGCNTGYTGYYTNGGNGAYTGGMGNGTNYTNGAYYTNYTNATH CARMGNGGNGCNAARGTNAAYGARCCNGAYGGNTAYCAYMGNACNGCNYTNCAYTAYGCN GCNGARCARGAYGARCARTGYGTNMGNATHYTNYTNGARMGNGGNCCNCARGCNAAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARACNGCNTTYGTN ACNGGNGGNGCNCARGGNYTNGGNCARGGNTAYGTNCARMGNTTYYTNGARGARGGNGCN AAYGTNTTYTAYGGNGAYATHAARGCNGARYTNGGNMGNTCNACNGARCARGARYTNCAR AGYAARTAYGGNAARGARMGNGTNGTNTTYTTYCCNTTYGAYGTNACNAGYGAYGARCAR TTYAARGARGCNTTYGAYCARGCNACNTGYMGNTTYGGNCAYGTNGAYATHATGGTNAAY AAYGCNGGNATHYTNAAYGARGCNYTNTGGCARAARATGATHGARGTNAAYTAYACNGCN ACNGTNMGNGGNACNCARYTNGCNATGGARCAYATGMGNAARGAYAARGGNGGNAARGGN GGNMGNATHATHAAYATHAGYTCNATHGCNGGNATGATHGAYCAYTAYTCNYTNCCNGTN TAYNNNGGNNNNAARCAYGCNGTNMGNNNNTTYTCNTCNTCNNNNGCNNNNACNGARGGN ATNGTNNNNNNNMGNGGNATHGARATHGCNNNNYTNTGYCCNNNNCCNNNNNNNACNNNN YTNNNNNNNAANYTNNNNGANNNNNNNYTNCCNGGNTAYAAYCAYGAYTTYGANNNNGTN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTNNNNNNNNNNGTNGAYGCNYTNTTYNNN YTNYTNAGYAARGARGAN---ATHAAYGGNGCNATHYTNNNNNNNNNNNNNNNNNNNAAY ACNTTYCARNNNATGNNNAARGTNGAYYTNGGNTCNGARTGGCCNYTNCCN--------- ------TGYGCNGARGAYTCNGARTGYCARGARCAYGARTGYTGYMGNMGNGTNGTNGGN CCNCAYATHACNAGYAARMGNGAY------------ACNTTYGGNYTNGARGTNGARMGN CAYCCNCARGGNACNTGYAARCCNTTYTCNTCNAAYGGNGGNCAYTGYGAYTAYTTYGGN ATHMGNAAYGGNTTYTGYGAYTGYGCNCCNGGNTAYTCNTGYMGN--------------- ------------------------------------------------------------ ---------------------GTNGAYTAYGAYAARATGGGNTTYGTNAARAAYAGYGTN ACNGGNATHGAYTAYGAYGARGTNTAYGARTAYGGNTGYTTYYTNYTNGCNCCNCARTAY GARATGGTNYTNTTYCCNGCNACNGCNCAYTTYYTNGAYGTNGAYACNGARATHTTYAAY AARGAYGGNYTNACNATHGGNYTNGARATHCAYYTNCARTAYTTYYTNMGNCCNAARGAR YTNGCNMGNYTNTAYYTNAAYTAYCAYGAYGAYTAYGAYAARYTNATHMGNYTNGTNGCN ACNAGYACNATHAARAAYAARGCNGTNCARTTYACNATGGAYGARTTYMGNYTNAAYMGN TCNTCNGTNGARACNGARYTNTTYAARGAYYTNAARTAYGTNYTNTCNGGNGAYTGYTGY CAYTCNTAYCAYGCNAAYCARTTYCCNACNTAYGGNGAYACNATHGGNAGYGARTGYGAY TCNTCNCCN------AARTGYAAYMGNGGNAARAAYGTNGAYGTNGCNTTYTTYCARATG GGNGCNATHACNATHCCNGAYGARGTNYTNAAYMGNTAYATGAARCARGARYTNYTNGAR ATGGARYTNGARGARGARTTYTAYAARCARGARAARGGNGTNGTNGARATGAARACNACN ATGYTNGTNMGNGAYATHTGGAAYGARGCNMGNGARATHAARGARACNGCNMGNGCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GCNATGAGYGAY YTNGTNCCNGTNATHGCNGCNGGNGCNGTNGCNAGYTTYYTNYTNYTNATHYTNATHATH YTNATHGTNTGYTCNGCNTCNGCNAARTCNTGGATHAARTCNATHAARAARAGYAAYGGN AARGTNAARATGCCNMGNTCNTAYTTYGARAARAARAARGARGCNAARMGNMGNYTNYTN GCNACNTCNGTNTCNCAYCAYACNGCNCCNATHGTNAAYGGNTTYCCNCCNGCNGTNCCN GTN---------------GCNGAYAARGARACNATGGTNCARGGNTGGAAYCARGGNACN MGN---------AARATHTAYGARGARAARGGNTAYACNATGGARYTNGGNGAYGARCAY GAYGAYGARTTYCAYATHGARACNACNATHGTNGAYAAYGARGTNYTNGAYGTNGGNCCN TAYACNAGYYTNGGNGAR---ACNAGYGCNAARCCNGTNAAYGGNAAYGTNTAYGCNAAY CCNTAYATHTAYTCNAAYAAYGAYMGNGTNACNGTNATHMGNAGYTCNGAYACN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CAYATHAGY TTYATGAARATHATGAARGCNGGNAGYTAYYTNAARAAYCCNGAYTGYYTNTTYATHGGN ACNAAYGARGAYGGNTGYYTNCCNCAYAARGGNAGYATHTGYATHCCNGGNACNGGNTGY ATGGTNGCNCCNGTNMGNACNGCNACNGARMGNGTNCCNATHATHATGGGNAARCCNGAR ACNGGNATGTTYGAYGTNYTNCARAARATHCAYAAYYTNGAYGCNTCNMGNAGYATGATG ACNGGNGAYMGNATHGARACNGAYATHGCNTTYGCNAARAARTGYGGNATGAARTCNTTY GCNGTNYTNTCNGGNCAYTCNACNMGNGARGAYGTNYTNAGYGAYGARAARGAYGTNAAR GCNGAYTTYTAYGCNGAYTGYYTNGGNAGYYTNGGNAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GGNGARTTYGGNTCNYTNGGNGGNYTNGCNGGNGGN ATGCAYTTYYTNCARCARCARCARCARCARATGGGNGGNGTNGGNGGNGGNGGNGGNGGN GGNGGNGGNATGGGNGGNATGMGNAAYGAYMGNAARMGNAGYGGNGGNCARATGMGNMGN GAYAAYGAYGARAARMGNGGNMGNMGNGAYTCNTGGGGNMGNGGNGARMGNGAYMGNTCN GGNAAYAAYAAY------MGNAGYGGNCARGAYMGNGARMGNAAYMGNTCNAGYMGNTGG GAYAAYAARGAYAAR---MGNMGNCAYGGNGARGAYTAYGAYCCNGCNGARCCNACNGAR GAYGAYGAYGARGGNGGNCAYAARAGYGGNGAYGGNTCNAAYYTNTAYTGYCAYGTNTGY AGYGTNTCNGTNTAYGAYGAYGARAGYTTYCARMGNCAYYTNAAYGGNYTNAARCAYAAR GCNMGNATGGARAGYATHGCNTCNGTNCAYCARATGMGNTCNACNCARYTNAARTCNMGN YTNAARGCNGARGARCAYYTNMGNAAYATHGARMGNAARGGNGGNMGNGAYCCNGAYTAY TTYTGYAARATHTGYAAYAAYGAYYTNGCNATHCCNTGGGARAARCAYMGNTAYTCNAAY ATHCAYAARCARMGNYTNYTNCARGTNMGNAARGGNTGYGGNTGGTGYAARGTNCAYGAY TTYACNAAYTTYACNGARGTNYTNGARCAYMGNGARACNGAYGARCAYAARAARAAYGCN GARYTNTAYGGNAARAARGAYGAYGAYAAR---GAYGAYGAYTCNCAYMGNCAYAGYMGN GAYGGNAARGARMGNGARMGNAGYAARTCNTGYTCNGAYAARGGNAARAARAGYGAYGAY AARAARGAYGARGTNGARGARGARGARGARGARGAYYTNACNATHCCNGARTTYAAYGCN GARGTNCCNGTNGGNYTNGAYTAYGTNATHCCNGTNACNGGNTAYTTYTGYAARYTNTGY CAYAARTTYTAYAAYAARAARTCNGCNMGNGCNACNCAYTGYCARAGYAGYGTNCAYTAY GARAARTTYAARGARGCNACNGARGTNAARATHGCNGCNMGNGARAARMGNAARGARGAR GARMGNYTNMGNAARGARAARGARGCNGARGARGARGARGGNACNGARGGNGGNGAYGAY GAYAARAARGAYGGNGARGAY------GARAAYGGNGARGARGTNAARGARGARTGYGAR CCNGARGTNAARGARGCNATGGARGARGARGARGARGARGARCARGAYGAYGGNATHYTN GAYGARGARGAYATHGARGAYATGGGNGGNGARGGNGARGARGGNCARGAYCARTTYGAR GARGAYCARGAYYTNTCNGGNAGYATHGGNGGNGAYGCNGAYCARGARGAYGARTCNGGN YTNAAYGTNACNATGGCNAGYTCNAGYTTYACNTTYGTNTCNGGNGAYATGGCNCARGCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARTTYYTNAARGARGTNCARAARTGYCCNGARCARTGYATHMGNTAY GAYMGNGGNGGNCAYCCNYTNYTNGTNCARAAYYTNGCN---GTNGARGARGTNGCNCCN GCNTGYTCNAARTGYGGNMGNGTNMGNGTNTTYGARYTNCARYTNGTNCCNGCNYTNATH CCNTGGYTNMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNGAYAARCCNACNATHTCNYTNTAY CCNTAYYTNATHAARTGYGARCARGTNGCNGTNCCNGAYTCNAARAGYGTNGTNGAYTCN GAYGAYGARYTNTAYGARMGNYTNATHAGYGARACNMGNGAYATHYTNGARAGYTAYGAY TTYCAYTCNGTNYTNAARGGNAGYATHGAYMGNGGNTTYAAYTGYGTNATGGAYACNYTN GCNGAYCAYTAYAARCARGCNACNGCNCAYGAYGTNTCNGGNGCNAGYATHCAYGAYGTN TCN--------------------------------------------------------- ------------------------------------------------------------ ---------------------------------------------AARTTYATHGARYTN GTNTCNCARAAYCCNYTNYTNTAYGAYCCNACNGCNAARCAYAGYGAYATHCARTCNACN AARGCNGTNTGGACNAARATHGCNGCNGARATGAAYGTNCCNTCNATGGGNGTNACNGAY TGGAARAGYAARTGGAARTGYYTNMGNGAYACNTTYGTNAARAARAARMGNGARATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GCNGCNACNYTN AGYATHGAYAAYCCNGTNTTYAARTCNTTYATHTGYTAYGCNACNGTNGTNYTNGCNAAR ACNATHYTNGTNGGNYTNATHACNTCNTTYCAYMGNATHACNAARAARGTNTTYGCNACN GARGARGAYGTNAGYTAYTTYGGNGTNGCNAAR------AARGGNATHGTNYTNAAYAAY ---CCNGCNGTNGARMGNTCNMGNMGNGCNCAYCARAAYGAYYTNGARAAYATHATHCCN TTYGTNYTNYTNGGNYTNYTNTAYACNGCNACNGGNCCNTCNYTNTCNGTNGCNYTNYTN CAYTTYMGNATHTTYACNGCNACNMGNATHATGCAYACNGTNGTNTAYYTNYTNCARGTN CCNCARCCNGCNMGNTTYYTNTTYTTYGTNATHGGNYTNTTYGTNAAYYTNTCNYTNGTN TTYCARATHYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNYTNCCNAAYAGYCCNATG------ATHATGACNTCN ACNCCNGCNGGNGGNCCNATGGCNGGNTCNCARGCNATGATHGGNGGNGGNAAYAAYCCN YTNCARGARGTNATHTAYTCNGGNAARCAYAAYGGNATHTAYATHTTYTTYAGYMGNATH YTNMGNCCNTTYTGGGAYAGYCCNGTNACNGTNGARTTYGTNCAYGAYTCNAARCARGGN AARGTNACNTTYYTNACNTCNAAYTTYAGYGTNGAYGARYTNTGYACNGCNYTNGARATG ATHMGNGAYYTNTCNGAYTTYGTNGAYTTYAAYTCNAARTTYGAYGTNGAYCCNCAYATH GAYATHATGAGYTCNGGNMGNGGNMGNYTNGAYGGNACNATHGAYGARCARAGYMGNAAR MGNATGCARATHGARGTNCARMGNATGGARAARATGTCNYTNCARCAYYTNCARGAYYTN YTNCAYMGNACNGARGARGTNYTNGGNYTNTGGMGNYTNYTNATHGAYCAYCARTTYCAY ATHYTNGCNTCNGCNATGGCNCCNGAYATHCARAAYCARYTNMGNAAYATGACNTTYAAR ACNYTNGTNACNAGYGGNAARGAYGTNTGYAGYACNYTNATHATHTGYYTNGTNAGYMGN TAYYTNAAYGAYAAYGCNACNATHGAYGCNATHAAYGAYMGNYTNMGNGARGTNTGYCCN ACNYTNTAYAGYACNGAYGAYGCNACNTGYTCNAARTCNAAYGARYTNYTNCARGCNGCN AARATGAAYCCNAAYCARYTNGARAARGARCARCARYTNCARGARGCNYTNCARYTNYTN AARGGNGTNTCNCARCCNYTNAAYYTNTCNGTNATHTGYTCNCARYTNGCNAGYGTNCAY TTYTAYYTNGGNATHGTNGARYTNGGNYTNAAYGARGCNGGNAARATHGAYCCNCARGGN ATGGCNGTNCAYTTYTAYAAYAAYGGNGARCCNCARGARGAYATHCARGGNATGCARGCN TAYATHGCNMGNATGGAYTGYTAYAARTGYATHACNGAYACNYTNACNTAYYTNTGYGCN GCNAGYACNAGYCARGCNCARGTNCCNGCNATHTCNTTYATGGGNTCNCCNCCNACNACN GTNGAYGCNAAYMGNATGGARCCNCARCARGCNGARTGYTTYAARGARGARGTNTTYCAY ACNGCNYTNMGNTGYGAYGAYCCNYTNTTYCAYGCNGCNYTNTAYGARTGGYTNTTYAAY ACNAAYCARGCNGARAARYTNYTNGARATHAAYACNCCNTAYGTNGARYTNTAYYTNMGN MGNAARGTNAAYYTNCARACNGARAAYACNACNGCNYTNGAYATGYTNTGGMGNCAYTAY GARAARGTNGARAAYTTYCCNGCNGCNACNMGNATHYTNTCNCARYTNGCNGARMGNCAY GGNACNAAYGTNAAYYTNACNCARMGNYTNGARTAYYTNTCNMGNGCNGTNGTNTGYGCN AARAGYTCNACNTCNMGNYTNGGNACNTCNGCNGGNGGNGARACNYTNCAYGARYTNGAR GARAARATGGARGTNGCNMGNYTNCARATGCARATHTAYMGNTGYYTNTGYAAYATGCCN GGNACNYTNCCNGTNGARAAYGCNAARGTNAARYTNGAYGCNGARYTNATGGAYATHACN ACNYTNTAYGARGARTTYGCNGAYCCNTTYGAYYTNCARGARATGAARYTNGCNATHGTN CAYTGYGCNGGNYTNTAYGAYYTNGCNYTNATHGARGAYYTNTGGGGNAAYATHATHGAY AARGARATHAAYAAYACNGCNCARATGTCNGGNGTNGAYMGNATHAGYACNATHGGNACN AARYTNACNACNGTNGCNAARYTNTAYGTNAGYGCNGARMGNTAYTTYCCNGTNGCNYTN ATHYTNMGNCAYYTNGARCARAARTCNTGYGARATGGAYYTNGAYMGNGARTGGGTNTTY AARATGATGYTNGARGTNGGNGTNGCNCCNGCNMGNYTNATGGARYTNTAYGAYMGNYTN TAYAARTCNAARGAYGTNATHTGGCARACNYTNAAYMGNCCNYTNCAYGTNYTNGCNGTN YTNCAYGCNTTYATHGAYCAYATGGCNMGNAAYCCNGTNYTNYTNMGNACNTCN---ACN CCNCCNATGCARGAYTGGTGYYTNGAYYTNGTNGCNTCNTAYYTNGTNGAYYTNGGNGCN YTNGGNGCNTCNTCNMGNGARGTNGCNGCNYTNATGGCNGGNTTYAARGCNACNCARGCN MGNYTNGARMGNYTNYTNTTYAAYATHYTNCARCARTAYGARAGYAAYCARGGNGAYTCN GAYYTNYTNYTNTAYACNCCNACNACNCCNAGYCCNGARGAYGTNAAYTGYCAYGTNGAR ATHCCNGTNACNMGNMGNGTNGGNGGNAARTGYGTNAAYYTNGGNTCNTTYATHGGNTGY CARGCNGGNATGTAYYTNGCNTTYGAYGCNATGTGYCARYTNGGNGGNACNGCNCCNGAR GARTCNGAYGGNACNAAYACNCCNGTNAAYMGNTCNMGNMGNMGNCAYCARAAYCCNTTY CARCARMGNMGNGGNMGNMGNYTNMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNAARGAYTTYCAYGTNCCNATHACNGTNGCNAARGGNCAYGARAARGTNMGNGARGAR TTYATGAARCAYAARCAYGTNTCNGAYATHMGNGTNATHGAYATGYTNGTNATHAARGGN CARATGGARYTNGTNGARACNGCNAAYATHTGGAARCARMGNCAYCAYATHATGATGTAY TTYAARGAYACNGTNAAYCCNAARCCNACNGAYTTYYTNAGYAARTTYTAYGARGGNCAR GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGCAYGCN AGYGAYAGYYTNTAYAARMGNATGTCNGGNCARCCNYTNTAYAAYAARGAYAGYATGGAY CCNGARYTNGAYCAYMGNGTNAARMGNGTNTCNGAYAARTTYTCNGARACNATHAAYYTN GTNGCNAAYGARCCNTCNYTNGCNTTYTTYMGNATHCARGARCAYGTNMGNAARACNYTN CCNCARYTNGTNGAYACNAARCAYGARGTNGARGAYGTNCARGCNAARGTNCARGGNACN TGYTTYGAYGCNGAYTAYGCNGTNAAYGCNGTNAARGCNATGCARGGNAGYGCNATHCAY TTYCARAAYATHCARGAYYTNYTNAARAAYGCNATGTTYATGAARCARCARATHTCNTAY GARGAYAAYMGNMGNAARCARGGNMGNAAYAGYCCNATGACNGGNGAYMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARACNGTNATHAARGCN YTNGTNACNGCNGAYGARAARTAYGTNYTNCCNAAYTTYGARGARATHCCNAARGARGAR ATHCARAARCARCARATGGARCAYTAYGARGCNTGYAARYTNCAYAARGARATGTTYGGN GGNATHMGNMGNYTNCAYGAYCAYGARTAYGAYCARATHTAYGGNGARACNGGNATHGAY GTNGAYGGNMGNCARAAYMGNATGATGYTNTAYGCNAARGCNATGGARAGYATHATHCAR GGNATGGTNTTYTTYGCNAARGCNATHCCNGGNTTYTCNAARYTNCCNACNAGYGAYCAR ATHACNYTNATHAARTAYTCNMGNCARGARTTYTGYTTYYTNAAYYTNTTYAARTAYGTN AAYATHGAYYTNAARGTNTAYMGNGGNGTNGARGAYYTNTGGCARTGYTCNYTNGARATG GARAAYTCNGARTAYMGNGAYATHYTNGAYYTNATHTTYTAYTTYYTNAGYAARTTYCAR YTNATGGAYYTNACNATHGARGARTGYGTNGTNYTNMGNGCNYTNGCNATHATGGCNCCN GAYMGNGCNAAYCCNGTN---ACNTCNCCNGAYGTNTCNGCNATHTAYGAYMGNYTNGTN GARYTNYTNATHTAYCARYTNGGNAARMGNTGYGAYMGNCCNATGYTNCAYTTYGCNMGN ATHATGAGYYTNATHACNGARTGYMGNACNAARGARGARGAYYTNACNACNATGTTYAAR ACNCARAAYYTNATHMGNTAYGTNAAYYTNGGNGAYAARCCNYTNYTNCARGCNATGTTY GCNGGNATHTAYAAYMGNGGNATHCCNGTNACNAGYTCNATGTTYGCNTGYYTNACNYTN GARGAYGAYCARAAYGARGARAARAARTCNAARMGNAARMGNAAYACNACNAAYGCNCAR AGYGCNGAYGCNAARAARAARGARGAYAAYAARAARAARMGNGAYGARAGYAARCARYTN CARCARYTNGCNTTYGGN---------------------AARCCNGGNTCNGGNAARAAR GGNAARGGNAARAAYGCNAAYCARAAYAARAGYTGGAAYAARTGGAARGARCAYGAYAAR GARGTNGTNGARGAYCARTTYAARGARGAYYTNGARAARGCNYTNYTNGARAGYCARYTN CARATGGARCARCARAARACNTCNGAYAARGAYAARAARGARMGNATHGARGCNGGNATH GARYTNCCNAARACNAARGARGARAARAARAARAARMGNCARAARGAYAARGCNAARGCN ATGTCNYTNGARGARTTYAARCARYTNCCNCCNCCNGCNMGNAARAAYTCNTCNGAYGAY TCNGARMGNGAY------------CCNTCNCCNCCNCCNGTNCAYTAYMGNGTNCCNTCN ACNGARCARGAYTCNAARTTYTTYAAYAAYGTNCAYAAYGARGCNAARCARATHYTNMGN CARGAYAARATGCARGARGARTAYMGNAARACNTAYGCNGTNGAYAAYGCNGTNGTNGCN AARYTNAARAAYGAYATHGARATHMGNGAYAARAARGTNGARGARYTNAARAGYCARATG GARAARATGGARGTNGARATGAARCARGTNAARCAYMGNAAYAARCARYTNTGYGTNATH YTNGCNCARGGNGARATGAARGAYAARGCNCARGTNYTNYTNCARGTNGAYGARYTNAAY AGYGTNAARGAYGARYTNATGGARCARGTNACNACNYTNACNGCNGAYYTNGARAARGAR AARTCNAARAAYMGNGCNYTNAARATGGARTCNGAYAARATGAARACNAAYAARCAYGGN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GGNGGNAARGAYAGYTGYTTY AAYATGATGATGTGYATHGCNGARGGNCAYGAYATHGTNGCNYTNGCNAAYYTNMGNCCN GARAGYMGNGAYGARYTNGAYAGYTAYATGTAYCARACNGTNGGNCAYCAYGCNATHGAY YTNTAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNACNTGGATHACNCAYGAY---AARAARMGNTCN TTYGTNMGNAAYGAYYTNACNTAYTCNAARGGNCAYATHGTNGTNCAYCAYCCNGGNGTN TAYCAYGTNTAYAGYCAYYTNACNYTNAGYTCNGTNGGNAAYGARAAYAARAARTGGGTN GTNGTNCAYTCNGTNACNAARTAYTAYAARACNCCNGARMGNACNYTNYTNTAYTCNCAR GTNAGYATHGGNGARGAYGAYYTNMGNACNACNAAYYTNGARGGNTCNTTY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TCNCAYTCNYTNCARGAYGAYYTNAARGARYTNAGYMGN GTNAARGCNGAYATHGCNAGYCARYTNGCNCARGCNACNGCNAARAAYCAYGAYYTNMGN CARGCNYTNGTNGARTTYCARCAYMGNGARAARGCNGCNAARGAYGARACNGARYTNTAY AARAARCARYTNTAYCARGARMGNAAYGGNYTNAGYAARAAYTAYGARACNYTNAARCAR GARYTNAAYGARGCNAARGTNMGNGARGCNCAYACNYTNCARGARGTNCARMGNAARTTY MGNGCNAAYAAYGCNGARACNGAYGCNGTNACNCARGCNYTNAARATGGARYTNTCNGAR GARAARTCNAAYAAYAARATHYTNGGNMGNAAYGCNGAYMGNYTNAARGARGARYTNGCN GTNYTNGARAARMGNTTYMGNATGTCNGARGARGARAAYGGNTCNATGMGNMGNAARATG GARYTNGTNAARAAYGARTTYGARGCNCARAGYCARYTNGCNGARGAYGAYYTNAAYMGN GTNTGYCAYYTNGARTCNCARYTNAGYGGNGCNCARACNGARYTNGARAARYTNGARAAR CARCARATHAAYYTNGTNCARGARATHGCNATHGARATHGAYGCNYTNGTNGARACNGCN TCNATHGAYGCNACNAGYAARTGYCARCCNATHAAYGGNYTNAARAAYYTNGCNACNGTN MGNTCNGGNATHCCNAAYCAYYTNYTNACNGARATHAARAAYAARYTNAARTGGYTNMGN TCNGARTTYMGNGARMGNYTNGCNMGNGARMGNMGNYTNMGNAGYGARTTYMGNACNGCN YTNTCNTCNTCNGARGCNGAYMGNAARTTYYTNATHGGNCARYTNGTNMGNAARGAYGAR GARYTNGAYGAYYTNGCNACNGARAARCARGARATHGCNTAYAARGARATHCARAAYCAR AGYTTYGTNGARGARYTNGARGARCARGTNTAYGAYYTNTCNGAYGARYTNCARYTNMGN AARATHMGNGARGAYGARCARMGNMGNATGTTYGTNMGNGARAARCARAAYATHATHGAR GARATGGARGAYATHATGGAYGCNGARAARGARAARGCNAARATHGARGAYMGNTAYMGN MGNYTNCARGAYACNYTNAARTCNYTNCAYCARGAYYTNAARACNACNAARATHGARAAR GGNAARAARACNAAYGGNATHYTNMGNTGYCCNTCNCCNAAYGGNACNCCNAARAARMGN AAYCAYGTNMGNATHTCNTCNACNACNCCNACNAARGARTTYGAYGCNGAYGARCCNGTN ------ACNACNTGYCAYACNCCNCCNCCNATGGCNYTNACNGAYGAYGARTTYMGNTCN AARTTYYTNCCNTCNACNCCNCARAAYATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG AGYGAYGARGAYMGNGARATHGAYATHGARAGYGAYGCNGAYGAYGARGAYGGNYTNAAY TCNTTYGGNCARGTNGAYGAYAARMGNGCNCAYCAYAAYGCNYTNGARMGNAARMGNMGN GAYCAYATHAARGAYAGYTTYCAYAGYYTNMGNGAYTGYGTNCCNCARGARGAYCARAAR GCNTCNGCNAAYTCNTCNAGYAARACNTCNMGNGCNCARATHYTNMGNCARGCNTCNGAY TAYATHATHMGNATGMGNGAYAARACNACNCARAAYGAYMGNCAYATHCARATHYTNAAR CARCARAAYGAYGARYTNCARGCNCAR--------------------------------- ------------------------------------------------ATHAARGCNYTN CARAARTCNCARGCNGGNGGNAARGGNYTNATHAGYTCNAGYTTYYTNGAYGAYMGNGGN GAYGAYGAYTAYGARAGYTAYGAYGAYGARCCNGTNGTNGCNTCNCCNCCNAARMGNAAR AARTCNAARAAYAGYCAYAGY--------------------------------------- ---------------------------------TTYATGATHGTNGGNYTNGGNAAYCAR CCNTTYCCNGARACNMGNCAYAGYGTNGGNATGCARGCNGTNGAYCARYTNGCNATHMGN YTNGGNYTNCAYTGGGARAARTCNCARGGNGGNYTNGGNGGNYTNYTNTGYAARACNGTN ATHAARACNAGYGAYGTNTGYATGGCNGARATHTAYYTNTTYAARCCNAARGCNYTNATG AAYATHAAYGGNGGNAGYGTNGCNMGNACNGCNAARYTNYTNGGNATGACNGCNGAYCAR ATHTAYYTNGTNCAYGAYGARYTNGAYATGGCNGTNGGNAARTGGGGNYTNAARYTNGGN GGNAGYGCNAARGGNCAYAARGGNGTNCARTCNTGYGTNYTNTCNYTNAARTCN------ ---------------AGYGGNYTNTGGGTNAARGARAGYACNGAYACNMGNAAYYTNCCN MGNYTNMGNYTNGGNATHGGNMGNCCNTCNTCNAARTCNGARGTNGTNTCNTAYGTNYTN AAYMGNGTNCCNTCNGARGAYYTNAARGCNATHGCNACNGCNACNGAYAARGGNTTYGAY YTNYTNYTNAARCAYATHGCNGGNAARGTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATH CCNAARATGTCNGARTAYAARMGNGARTTYCARCCNTGGAARCCNYTNGAYGTNGGNGGN AGYTTYAAYYTNAAY---------------GCNGAYAARGAYGTNGGNAARAARCCNATG GTNAARMGNAGYAARAGYGCNGGNGCNGAYYTNMGNAARGCNAARCCNAAYGAYTCNTGY GCNAARGARGARGGNAGYGGNGARGCNGARYTNAARGARAARYTNACNAARAGYCAYGGN AARATHMGNMGNYTNGGNTCNGARTAYCARGCNAAYTTYAARGCNCCNACNAGYTAYTAY AGYAGYAARGGNGCNTGGAARGGNGCNGAYCCNCCNCARATGATGCCNCCNACNGARAAR AARGAYGTNGAYAGYAARAARGAYGCNAGYGAY------------TCNGAYAGYGTNCCN ATGTCNAAYTGGTTYGCNGARGTNGTNGARYTNMGNMGNMGNGCNGARGARTAYMGNAAR MGNGCNCARGGNACNCAYTTYTCNMGNGARCAYYTNGTNCARYTNATGGCNAARCARACN GARTGYTGGGAYYTNGAYTCNCARGTNTCNTCNACNGTNMGNGCNYTNGAYYTNGAYGCN CCNMGNATGGAYAARMGNGTNACNMGNCARMGNMGNGAYTCNCCNATHYTNTCNGAYGAY GTNGARGTNGARGAYYTNGAR------------GARGCNGCNGARGTNAGYGAYCARGAR GTNAARGARCCNAARAAR------------------------------------TCNTCN GCNTCNACNMGNAAYGGNMGNAARATGACNMGNYTNMGNGARGAYGGNCARGCNYTNACN MGNCARCARMGNAARATGAARGARCARGCNMGNAARGARGARATGGGNGARAAYGAYGAY GGNGAYGAYGAYGTNGTNGARGARGGNGARGGNMGNCARCCNACNCCNACNYTNAARCAR AARAAYAAYTCNGCNTGYMGNCAYCAYYTNGAYYTNACNACNCCNGCNGTNGGNGGNGCN YTNYTNAGYTGYCCNCCNGCNMGNAAYACNAARATGATHGTNACNTCNMGNTCNGGNGAY AGYTAYGTNACNGCNTCNGAYAAYATGGARGTNCCNCCNGTNCARAARAARGTNGAYATG GAYCAYYTNAAYACNMGNCCNATHYTNGGNCARCCNTCNGGNGAYTCNCAYCCNYTNMGN GAYGAYGAYGCNTCNAGYGAYMGNGCNYTNAAYACNMGNTAYGTNCCNACNCCNGTNATG GTNAAYGGNGAYGARGAYAARGARAAYTCNCCNCCNTCNAARCCNCARGCNAARGGNGGN AARCCNAGYATGYTNACNCCNGTNCARGARGGNGTNGGNAARACNTAYATHAARTCNAAR CCNTTYYTNACNATHGARGAYGTNCAYGCNAAYGCNAAYCARAAYGTNGAYGAYGAYGCN ATGTCNGTNTCNATGATGTCNGTNGCNTCNAGYGCNTCNATGGCNTCNGARGTNYTNGAR MGNGCNMGNAARMGNAAR---GARTTYTGG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARGGNACNGARGTNGTNAARGCNGCN ATHACNAARATGAARTTYAAYAARCAYATHAARMGNGCNGARGGNCARAARCCNCARAAR GTNGARYTNACNATHTCNGCNGAYGCNGTNAARATHYTNGAYCARAARCAYAARGTNATH YTNTAYCARTAYCCNYTNCAYMGNATHTCNTAYTGYGCNGAYGAYAARTCNGAYAARMGN ATGTTYACNTTYATHGGNAARGCNGCNGARAAYAAYGAYCAYTTYTGYTAYGTNTTYGAY AGYGARAARTGYGCNGARGARATHACNYTNACNATHGGNCARGCNTTYGARYTNGCNTAY AARMGNTTYATHGARTCNTCNACNCARGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARGAYCCNTGYCCNCARTCNCCNYTNTCNMGNGGNGTNAARMGN ACNCAYGARGARATHGARGARCCNAGYGARAGYTCNCCNTCNCCNAARCCNTCNCCNCAR AARAAYAARAARMGNTGYTTYATHTGYAGYTGYAARYTNGARYTNGCNCARMGNACNATH GGNAARTGYMGNTGYGARCAYGTNTTYTGYCCNATHCAYMGNYTNCCNGARYTNCAYGAY TGYGTNTTYAAYCAYAARGARGAYGGNMGNMGNGARGCNMGNGARAARATGGTNAARCCN ACNMGNCAYATGGGNACNTCNTTYMGNMGNGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGTCNGGNATHACNTGYYTNGCNTGYAAYGTNGTNTTYGTNGAY GTNGARYTNGGNMGNGTNCAYTAYAARACNGAYTGGCAYMGNTAYAAYYTNAARMGNAAR GTNGCNGGNYTNTCNCCNATHACNYTNGARAARTTYGARGARMGN---------CARAAR GCNCARGAYCARYTNGAYTCNAGYCCNACNCAYGARAGYTGYGTNTGYAARCCNTGYAAY AARTCNTTYAAYAGYTCNAAYGCNTAYGARAAYCAYYTNCARTCNAARAARCAYAARGAY GARACNTCNAARAARGGNAARAARAARAARAARTCNMGNGCNMGNGGNGGNCAYTCNCAR GTNGCNAGYCARAARGAYGARMGNAAR---------------GARGARAAYATGTCNGAR GAYGARGAYGAYTCNGAYCAYGARTCNTGGGAYAGYTAYGAYGARAAYGTNYTNGGNATG GARGARTGYYTNTTYTGYTCNTTYATHAGYCCNTCNYTNGARGAYAAYYTNACNCAYATG ACNTCNGARCAYGGNTTYTTYYTNCCNGAYGCNGAYTAYATHAGYGAYYTNGARGGNYTN ATHACNTAYYTNGGNGARAARGTNGGNGCNGGNCAYGTNTGYYTNTGGTGYAAYGARAAR GGNAARMGNTTYCAYAAYTGYAARGAYGTNCARAARCAYATGGTNGAYAARGGNCAYTGY AARATHYTNCAYGARGGNGAYACNYTNTAYGARTTYGCNGAYTTYTTYGAYTAYTCNAAR AGYTAYCCNGCNGCNGARAAYGARAAYTCNGARACNGCNYTNGTN---GARTCNGTNGAY GTNACNGARYTNGAYGGNGAYGGNTTYTCNYTNACNYTNCCNTCNGGNGCNGTNATHGGN CAYMGNTCNYTNATGMGNTAYTAYAGYCARAAYYTNGTNCCNCARATGMGNGARMGNACN MGNAAYGTNYTNCCNAARATGYTNGCNCAYTAYAARGCNYTNGGNTGGACNGGNGCNACN GGNYTNCARGTNGARCARMGNGCNAARGAYYTNMGNTAYATGCARMGNGTNMGNAAYMGN CAYCAYATGMGNYTNGGNGTNAARGCNAAYAARYTNCARCAYCAYTTYMGNGAYGCNAAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TTYGGNGTNTAYYTNATHCARACNYTNTAYCCNYTN GTNGARAAYYTNGGNCAYGARAAYATHCAYATHAGYAGYACNGCNTTYYTNGCNYTNACN CARATHTGYTAYGCNTGYAAYTAYMGNTCNATHGAYGAYYTNATHCARGGNAAYGCNGAY TAYYTNATHAAYAGYGTNTCNYTNMGNYTNMGNCAYTTYAAYCARAAYCARMGNACNCCN MGNYTNYTNTCNGTNATGYTNMGNTAYTGYTCNATGGARYTNYTNCCNYTNGTNGARCAY AGYGTNGGNGARATHYTNGAYAGYYTNGAYGAYCAYTAYACNAAYGAYYTNGTNYTNTTY ATGCCNGTNYTNYTNGARYTNACNTCNGCNATHGGNMGNTGGTTYCCNMGNAAYACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TTYCARTTYGCNGGNNNNGAYTAYGGNCCNGTNGAYTTYCCNAGYACN YTNCCNGCNGAYYTNCARGCNGGNATGGCNTTYGCNGGNGGNGGNCCNGTNTTYCCNCAR AAYCARMGNGGNGGNACNTAYGGNATGCCNCCNTTYCAYATGAAYTAYTCNCARCARGCN TCNATGCCNTCNATGTCNACNYTNCCNTCNAGYTCNTTYMGNAGYMGNTTYAGYGAYTTY CCNTCNGAYCARAGYCCNCAYYTNCCNATGCCNATHCCNTCNCCNGCNTCNGGNATGATH GCNGAYMGNYTNCCNAGYTTYAGYACNATHGTNTCNAGYAGYGGN------GARYTNTCN AARAGYAGYCARGCNYTNTAYTCNAGYATHGCNACNTCNYTNTCNGCNCARCARCAYGCN TTYCARCCNTCNTCNMGNGGNGCNYTNCCNTCNCAYTTYGAYGCNTCNTTYCARGAYCAR GTNGCNTCNAARAGYTAYAGYAARTCNTCNCCNYTNGGNTCNACNTCNCCNGGNATGAAY AAYAGYAAYAAYAAYATHCCNCAYTCNTCNGTNATGCARGGNTCNTCNCAYAAYGGNAGY CAYCAYYTNCCNTCNYTNTCNCCNMGNTCNTAYAARGGNGAYAGYATHTCNCARCARGCN TAYYTNGGNGCNATGAAYYTNGARMGNCAYGGNACNTTYCCNCAYGGNTCNYTNGCNGGN TCNCARGGNCARGARTCNATGACNYTNCCNAARTTYAARCAYAARTAYYTNTCNCAYACN CARYTNGCNCCNMGNMGNCCNAAYGGNACNTTYAARTTYTTYYTNYTNGGNMGNACNGAR MGNCARACNATHTTYAAYMGNGGNACNCARACNAARGARGARTCNATGTCNCCNAGYTTY ATGGAYTCNACNGGNAARGCNACNATGACNACNTGYGTNGCNAAYAARGCNACNATHGTN ACNGTNGGNATHGTNAGYMGNCCNGCNAAYTTYGGNGGNGCNGARYTNACNCAYAGYTCN CCNMGNGAYATHATGGCNACNGGNAAYGGNTAYTCNGAYCARCAYTAYAAYCARCAYAAY GARAAYTAYGAYCARATHATGGARGARMGNAARGCNAARGCNMGNGAYYTNGARCARGAR MGNATGGARGTNAGYGTNMGNATHGAYGAYACNCARTAYGTNAAYGTNGGNAAYGTNAAR MGNTGGCARTGYAAYGARTGYGARAARTCNTAYACNACNAARCAYAAYYTNGTNATGCAY GTNYTNGAYCAYAGYGGNATHAARCCNCAYYTNTGYYTNAARTGYGGNAARTAYTTYAAR CARYTNAGYCAYYTNAAYACN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARGAY CCNAARAGYGTNATHAARTAYYTNYTNAGYTCNCCNACNGCNGGNTCNACNCAYCARATH TCNACN---------CCNYTNGCNCARCCNATGCCNGCNCARGARACNCCNGARTCNGCN GCNCCNGTNAARAARTCNAGYAARAARATHAARTTYGARGAYAARATH---------ACN CCNGGNGTNAARGCNAARGARAARAARATGAARATHGARATHATGTCNCCNTCNGARYTN GGNCCNCCNATHTCNTCNACNCCNATHCCNGAYGTNAARGTNCCNAGYYTNAARATGAAR ATHATGTCNGGNTCNAAYCCNATGACNGCNCARGTNGCNYTNTCNACNGGNGAYGGNGCN GCN------GGNCARACNCCNAARACNAARAARTCNAARAARGCNAARGCNCCNGTNGAR ATHGAYGAYGAYGTNAARYTNGARATH------------------------GCNGAYGCN GGNACNGARGARAARGCNCCNAARAAR---AARAARGTNTCNAARAARAARGARAARYTN ATHCARGAYGCNATHAGYGCNGCNCARCARATGCCNAAYYTNGCNGCNYTNGTNGCNTCN CCNCARGCNYTNGGNGTNYTNGCNGCNGAYTCNCCNTCNCCNACNGTNCARAARCCNACN ---------AARAARAARATGAARAAYTCNTCNCCNGCNGCNTCNGAYGTNAAYACNAGY GAYTCNYTNGTNATGGAYGAYATHGGNATGGARGARGAY---GARGGNGARGARTCNACN YTNGTNATHGCNGARACNGARAARAARAARAARAARTCNTCNGTNAARAARAARGTNCCN AARGAYAARGAYGGNGTNGTNAGYCCNAARCCNGARAAR---GARAARAARATHCCNAAR MGNGCNCCNACNGCNTAYATGYTNTTYTGYAAYTCNCAYMGNCCNGCNATHGTNGCNGAR AAYCCNGGNATHGARTTYGCNAGYATHAGYMGNAARYTNGGNGARYTNTGGCARATGCAR TCNAAYAARCARAARYTNCARTGGMGNMGNAARGCNCARMGNMGNATGAARAARTCNAAY YTNATHTCNACNGGNAARGTN---GGNAARGARTCNCARGCNACNGCNTCNGCNTCNCAY GTNACNGGNCAYATHAAYTCNACNAAYCAR------AARYTNGCNYTNATGYTNCARAAR AGYAARCCNGTNGCNATGGAYGARGGNCCNYTNAGYCCNACNAARAAYTTYAGYATHGAR CCNYTNGAYGTNGCNGCNCAYYTNAARYTNYTNGGNGARTCNYTNAGYATHATHGGNATG MGNYTNCARGARCAYAARGGNATGATHGCNGTNCARGGNAGYYTNTCNGTNYTNYTNGAY TCNYTNYTNTGYGCNTGYGGNCCNYTNYTNTGYYTNACNCARCARGTNCCNGGNATGGAY GGNTGYTCNCCNYTNGTNCAYGCNCARACNYTNGAYAGYGTNGCNTAYGTNATGCCNGGN YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNMGNCARCARMGNMGNGTNAAYTCNGARTCNMGNYTNAAYGCNGAYCARYTNTAYGGN AAYTCNGARGGNGGNYTNATHACNYTNATGGGNCARCCNCARCCNGTNMGNGCNCCNMGN CAYMGNTCNYTNCCNGARYTNCARGGNAARGARTCNCCNMGNAGYGTNAARTCNGCNCCN TGGGARTCNAARTAYGAYTAYGGNYTNTAYACNTCNGGNCAYGARTCNGARMGNCCNCAY CAYGGNMGNCAYCCNMGNGCNGTNTCNGGNAGYGAYAGYGARAGYGGNATHMGNCAYMGN AARAARTAYTTY------------AGYATHCAYCCNAAYGCNCCNCCNCCNCCNTAYACN ACNGGNTCNCCNGCNTAYCCNCCNCCNCCNCCNGCNGGNTAYTAYGGNGCNCCNCCNCCN CARGCNTAYGGNGGN------------------CCNCCNCCNGGNTAYGGNGCNCCNCCN CARCCNGGNTAYGGNGTNCCNCCNCCNGCNGGNTAYGGNCCNACNCARCCN--------- ------GGNTAYGGNCAR---------CCNCCNTAYCCNCARCARCARTAYAAYCCNCAR ------------GGNCCNTAYCARCAR------CCNCARCARGTNGTNTAYGTNMGNGAR GARMGNMGN------GARAARGAYAAYTCNGCNGARACNTGYTGYATHGTNGCNYTNTGY AGYGCNYTNYTNTGYTGYTGYYTNATG--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGTCNCARAARGTNTAYNNNTCNGGNTCNACN TTYCCNGARYTNACNNNNGGNYTNYTNMGNATHTAYAGYAAYMGNYTNTGYCCNTTYGCN GARMGNACNMGNYTNGTNYTNGCNCAYAARAAYATHCCNCAYGARGTNGTNAAYATHCAY YTNAARGARAARCCNGARTGGTTYYTNGCNYTNTCNCCNGCNGGNAARGTNCCNGTNATH CARYTNGAYGAYYTNATHYTNAAYGARTCNACNGCNGCNTCNGARTAYYTNGAYGAYGTN TAYCCNGGNGAYMGNYTNCARGCNNNNGAYCCNCAYMGNAARGCNGTNGAYMGNATHYTN YTNGARAAYTTYGGNCARGTNACNATGYTNTTYCAYTTYYTNTCNYTNYTNATGTGGGAY GAYAARAAYAARGAYGARATHGARCARAGYTAYAARTTYTGYGARGARGARYTNGTNAAR MGNGARAGYCARTTYTTYGGNGGNTCNAARCCNGGNYTNATHGAYTAYTAYYTNTGGCCN CAYYTNGARMGNGTNCCNACNGCNATGYTNATH---CCNAARYTNGCNYTNACNAARTCN GAYTAYCCNAARATGTCNAGYTGGTGGGARGAYATGACNCARGTNCCNGCNGTNAARAAR GARTTYTTYGAYGCNGAYTGGCAYTAYCARGTNTAYAARATGMGNAAYGARGGNTCNCCN TAYTAYGAYTAYGGNYTNTTYGGNMGNTAYGCNMGNGARTAYAAYCCNAARGTNCAYGGN CCNTAYATGCCNGGNMGNTTYTAYGGNAARCCNGAYACNCCNGTNGGNCARGTNAARYTN GGNGARYTNGGNACNTGGTTYGGNMGNMGNAAYAARAGYCCNCARTCNATGTGGAGYTGY GTNCAYMGNGCNTAYTGGMGNTGGGCNGCNAAYAAYYTNCAYGTNMGNCARAGYGGNTTY GTNCCNATHGGNCARGCNGCNATGGTNYTNTCNATHGCNTTYTTYGCNYTNYTNCAYAAR GARMGNAGY--------------------------------------------------- ---------------------------------------------------GGNYTNGGN GAYGAYYTNAAYAARTAYAARAAYYTNCARGAYGARAGYACNGCNGAYATHCAYCARAAR AAYGARCARYTNAARGAYCARGARTTYGARYTNTCNGARACNMGNCARCAYYTNGTNATH GCNCARAGYCARYTNGARGTNGCNAAYGARACNACNGARAARCARGAYTCNTCNYTNGCN GCNATHAARCARAARTAYAGYCARGCNACNACNCARATHGGNCAYYTNGARGCNACNGTN AAYACNYTNCARGAYAARYTNACNGARAGYMGNAGYMGNGARATHGAYAARGARCARACN GTNGARAAYATGMGNGCNGARYTNGARGGNYTNGAYCAYGCNTAYTCNGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGCNTCNACNTCNCCNAARCCNAARAARGGNATHYTNAARAGYTCNAGYAGYATHGAY CAYAGYAARAARGARATHGARTGGGAYGARATGAAYATHYTNGCNACNCAYCAYCCNCCN GAYAARGAYTAYGGNTTYATGAARGTNGAYGARCCNCCNACNCCNTAYAAYMGNGCNGCN ATGTCNGAY---GARGARGGNGARGGNGGNAARGARMGNAARGGNAGYGTNGAYMGNATG ACNGGNYTNGAYCCNAGYGAYYTNGCNTCNMGNYTNMGNTCNGARGGNGAYGAYAARMGN AARAARAAYTAYGAYGARGAYGAYGAYGAYGAYGAYGAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------ATGGAYACNMGNTGYGCNGGNGAYATGMGNATHAAYCARTTYGAYATHGGNGAR ACNATHGCNCARMGNMGNMGNMGNGCNGGNGTNTAYAARAAYTGYTCNGGNCCNCCNCCN GARMGNMGNAGYACNATHAGY------ACNATGACNAGYAGYTAYCARGTNACNMGNATG MGNAAYYTNTCNGGNGGNAGYAAYGGNAGYACNGCNAGYGGNAGYAGYAGYGGNAGYTCN ACNCARYTNGAYAAYCARTAYTCNTCNACNGAYAAYCAYYTN---TAYYTNCCNYTNGAY ATHTCNCCNTTYGCNAAYTCNTCNGAYGCNCCNCARCAY------MGNGAYGAYTCNTCN YTNTCNCAYMGNAARYTNGAYMGNAGYYTNAGYGAYAGYGAYAGYGAYMGNTCNGGNAAY GGN------TCNTCNCAYMGNACNGTNAAYTCNAGYMGNTAYAARACNGARYTNTGYMGN CCNTTYGARGARAGYGGNTCNTGYAARTAYGGNGAYAARTGYCARTTYGCNCAYGGNGCN CAYGARYTNMGNAAYYTNGCNMGNCAYCCNAARTAYAARACNGARYTNTGYMGNACNTTY CAYACNATHGGNTTYTGYCCNTAYGGNCCNMGNTGYCAYTTYATHCAYGARGAYGAY--- ------------------------------------------------------------ AARYTNGCNGAYAGYGGNAGYYTNAGYCCNCCNYTNAGYCCNACNGGN------AAYGAY CCNAAYAAYTTYTCNTAYTGYTCNGARTCNACNTCNCARYTNAAYATHGARAAYGCNCAR ATHAAYAAY------TCNYTNACNGTNAAYATHAAYAGYTAY------AAYGGNAAYGTN GAYYTNCARTCNYTNGAR---CARGGNTTYAAYTCNGCNYTNAAYYTNAAYMGNCARTGY AGYGARTCNACN------------------MGNAAYGTNTTYAAYAAYGCNTCNACNTGY AAR---------GGNGAYGARTAYGAYATHTTYAGYTCNATHACNGTNTTYAAYCCNGCN GARGTNGTNGTNGAYAAYGCNCCNAARCCNTCNAAYTCNTCNTAYTCNTCNTAYTCNGAY CAR---------GTNGAYAAYTAYCCNACNTAYGTNGAYACNAAYTCNTTYTGGCCNTCN ------AAYATGTCNTCNCARAGYATGGCNCCNGCNGAYCCNTTYAAYTAYTCNCCNACN GGNTCNACNGGNTCN------------------------TCNAGYTCNTCNGGNGAYTGY GGNGGNAGYACNGARAGYYTN---------------------AARMGNACNGCNTGGTGG AAYGAYYTNGTNAARYTNAARGTNAARGARAARAARGARGCNTGGAARAARTAYYTNGCN ACNCARAGYACNCARGAYYTNGARTTYTAYAARACNAARMGNAARGARGCNAARGAYGAR GTNAARYTNTCNAARCARACNCARTGGGARATHTTYGGNGARAARYTNGARCARAAYTAY MGNGARAAYCARAARYTNTTYTGGGGNGCNGTNAARMGNTGYMGNMGNGGNAAYAGYTGY CCNGTNAARCAYGTNAARGAYAARCARGGNGARGTNGTNAARGAYAGYGAYAARATHYTN GAYGTNTGGCARGARTAYTTYCARAGYYTNCAYAAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARGARMGNGAYYTNTAYATGAGYMGNGARAAY CARCARGARYTNAARCAYMGNYTNAAYCARGARGGNATHGGNGARATHMGNYTNCCNCAY ATHTTYGCNGAYGGNATHCAYATHGGNGGNGCNGGNGARYTNGARMGNYTNAAYGARGCN GGNGARYTNMGNGCNYTNYTNGAYGGNTAYCARAARATHAAYGCNMGNTTYGCNTGYGAY GGNTGYGGNGGNTAYMGNTTYATGCCNTGYGARATHTGYCAYGGNAGYAARMGNTCNYTN YTNMGNAAYCAYTTYACNCARGARYTNGTNGCNYTNMGNTGYATGCAYTGYAAYGARAAY GGNYTNMGNMGNTGYGARYTNTGYMGNGAYCARCARGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARGTNATHTTYGARAARGCNGTNTGYYTN ATHGARGARGGNCCNGTNATHYTNTTYATHGAYGARATHGAYATGYTNTGYCCNMGNCCN GARACNGCNAGYYTNGGNAAYMGNCARYTNAGYAAYGCNYTNATGACNGARATHGAYGCN ATHCAYAGYAARCARATHTCNGGNYTNYTNGTNYTNGCNACNACNAAYTCNATHTCNAAY GTNGAYCCNMGNYTNMGNMGNCCNMGNMGNTTYGAYCARGARATHYTNATHAAYGTNCCN ACNGARGCNCARMGNYTNTCNATHYTNCARGTNYTNACNGGNTGYATGAGYYTNGCNTCN AAYGTNTCNTGYACNGCNYTNGCNCARATGACNCCNGGNTAYGTNGGNGCNGAYYTNMGN GGNYTNTGYGARGARGCNATHAGYCAYGCNCARACNYTNCARGGNTCN------------ ACNGTNGTNAAYATGGAYGAYTTYGAYTAYGCNYTNCAYAARATGATHCCNTCNYTNAAR AARGGNATGGAYTGYGTNGTNGAYATGAARCCNGTNAARTGGACNGARATHGGNAGYYTN GAYGARGTNAARGCNGARATHAARCARTCNATHGARTGGCCNYTNAARTAYCCNGAYGTN YTNMGNAGYATGGAYATHCCNCCNGCNAARGGNATHYTNYTNTAYGGNCCNCCNGGNTGY TGYAARACNACNYTNGTNMGNGCNGCNGCNACNTCNTGYAAYGTNTCNTTYYTNTCNYTN AGYGGNGCNCARGTNTAYTCNGCNTAYGTNGGNGARTCNGARMGNYTNATHTCNCARGCN TTYCARAARGCNMGNGCNYTNGCNCCNTCNATHYTNTTYYTNGAYGARATHGARTCNYTN GTNGGNAARMGNACNGCNAAYGTNGGNAAYAGYMGNGTNCARGARMGNATHYTNTCNACN ATGYTNAAYGARATGGAYGGNGTNGGNAAYMGNYTNGAYYTNAARTTYGAYTCNACNGTN TCNCAR------------ACNGARAAYAGYAAYTCNGGNACNCARAARATHATHGARAAY GAYACNAAYGCNGARGARTGYCCNATHAARGTNAAYGARTCNGARGCNGGNAGYAGYYTN AAR---------GTNATHGTNGTNGGNGCNACNAAYMGNCCNGAYATGYTNGAYCCNGCN ATHYTNMGNCCNGGNMGNYTNGAYAARCAYATHTAYGTNCCNCCNCCNGAYGAYCARGCN MGNAARGCNATHYTNCARATHTTYACNTCNAARATGTCNTGYYTNGAYGTNAAYATHGAY TTYYTNGTNGGNAARACNGAYATGTAYAGYGGNGCNGAYYTNAARAAYYTNTGYAARGAR GCNGGNYTNCARGCNYTNMGNGGNCARYTNAAYGAYACNAARTCNATHGAYGAYCARTGY GTNTCNAAYMGNCAYTTYCARYTNGCNYTNGAYAARGTNAARCCNTCNYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNGAYAARTTYGTNGTNGGNCARGGNATGAARGTNGTNGGNAARAARATHATG TGYGAYCARTTYGTNGCNGGNCCNTTYTTYTGYACNACNTTYYTNTTYGGNACNACNYTN YTNGARGGNAAYGGNGTNTCNGGNGCNATGGCNGARTGGAARGCNAARTTYYTNCAYATH TAYATGGTNGAYTGGGCNTTYTGGCCNGCNGCN--------------------------- ------------------------------------------------------------ ------------------ATHGTNTAYAGYYTNATHGARGARYTNTTYCCNTGGYTNYTN AAYMGNGARCAYYTNMGNAAYAGYGTNCAYMGNTTYTTYACNAGYYTNAARCARGARCCN TGYATHACNATGTTYTAYTCNYTNYTNYTNGTNTTYGGNTTYYTNCCNTGYYTNGGNTTY TGYATGTTYATHGGNGGNAGYTTYTTYATHACNATHGTNTGYTTYGCNGCNTCNCARYTN TTYATGGTNYTNYTNGCNGGNTTYATGTTYGGNGGNATGTTYGTNTTYYTNGTNGGNGTN TGYTTYACNGTNGCNATGATGTAYGGNTCNTTYGTNCAYTTYYTNTAYTGYTGG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ACNYTNTCNAARYTNAARCARMGNMGNATGYTNGARGARAARATHGCNYTNAAR MGNTCNMGNCARYTNGARGARYTNGARAARAARCARAAYGCNGARYTNCARAARCARMGN MGNATGGCNGARAAYAAYGGNGARGAYGARGAYGAYGAYGTNCAR---YTNCARGTNGCN ACNATGAARAARCAYGTNCARCARAARATHGCNYTNGCNCARGGNCARGARYTNGAYATG GARGARGARYTNGARGARATHMGNATHGARATGACNAARGAYMGNGCNYTNGCNYTNAAR GAYCARGARGARMGNYTNGGNGCNYTNATHGCNTCNYTNCARATGGAYAARGCNMGNGAR YTNGCNAARATHGARGARCARCARAARGCNATHAAYAAYYTNAARTCNAAYYTNATGGAY GAYYTNAAYGCNMGNGGNATHYTNTCNACNCCNGARTGYCARAARATHYTNAAYGTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ACNGCNAARCARAARGGNATGTCNATHTTYYTNGAYGTNTTYMGN MGNGCNGAYAARAAYGAYGAYGGNTTYATHTCNTGGGARGARTTYGTNTCNTTYTTYGCN GAYGGNGTNATGGGNAARGARGARYTNCARACNYTNTTYAAYCARATHGAYTCNCAYAAY ACNGAYAAYATHGAYATHGARGARYTNTGYGCNTAYTTYACNGARCAYYTNGGNGARTTY CARGARATHTTYAGYGCNATGGARGARATGAAYAARAARATGACNAAYGTNYTNTTYAAY ACNTCNAARGTNTAYCARGGNTCNTCNMGNACNGAYAARTTYGTNACNMGNTTYYTNATG MGNGARACNYTNAAYCARATGATGGCNYTNCARCARCCNYTNGAYGCNGCNGCNGARACN YTNGAYAAYCARGCNMGNGARGARMGNTCNGAYATHYTNCCNYTNGARGTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GAYATHTAYCCNGAYGCNMGNAAYCAYTAYATHCARYTNAAYACNYTNGAY AAYGGNCARAGYTAYAARGCNTTYYTNGTNTGYGAYGGNACNAARMGNACNAAYGAYGTN AAYTTYATHATHGGNAAYYTNTGYGAYGAYTTYAAYGARACNTCNMGNGTN--------- ------GGNGAYAARATHGAYCCNGTNGARATHTCNMGNACNGAYACNTTYACNATHYTN GGNATGYTNAGY---------GCNATHYTNTTYTCNTCNATHGGNGTNATHYTNGTNGCN GTNGTNGCNTAYTAYACNTGGAARAARTAYCARCAYMGNCARMGNATHYTNMGNATHTTY MGNCAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARAARAARACNCCNMGNAARGGNAARGGNTAYGCNTCNACNYTNGARAGY CCNGGNGGNCCNTCNGCNGTNMGNACNACNAGYTTYAGYCAYATHTCNTGYGTNGAYYTN ACNATGAARTGYYTNGAYAARACNAAYTTYCAYYTNGAYMGNYTNCCNCAYYTNTCNCCN YTNTAYGGNCARATHTTYATGMGNYTNAARTGYGTNATGGARGCNAAYGTNGARGARAAR GGNTTYYTNACNATGTTYGARGAYGTNAGYGGNTTYGGNGCNTGGCAYMGNMGNTGGTGY GTNYTNTCNAGYAAYAARYTNTGYGTNTGGAARTAYCCNGAYGAYGARACNMGNAARGAY CCNATGACNATGATHGAYYTNAARMGNTGYATHACNGAYAARGTNGGNYTNGTNCCNMGN GAYATHTGYGCNMGNCCNAAYACNTTYGARATGGTNACNGTNMGNCARCCNYTNAARGGN GARCAYGAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GCNAAYATHATHGTNTTYCCNGARGAY GGNYTNTAYGGNGAYCCNGAY---TCNMGNAARATHATHTTYCCNTTYYTNGARMGNATH CCNGAYGCNGARGTNGTNCARTGGTCNCCNTGYTCNGAYCCNACNMGNTTYCCNGAYACN GARGTNCARYTNGCNYTNAGYTGYATGGCNAARGAYAAYAGYYTNTAYYTNGTNGCNAAY ATGGGNGAYTAYGTNCCNTGYAAYGCNAGYYTNGAYCCNAARTGYCCNGCNGAYGGNMGN TAYCARTAYAAYACNGAYGTNGCNTAYGGNCCNGAYGGNAARTAYYTNGCNAARTAYCAY AARACNCAYYTNTTYTAYGARTCNCARTAYGAYACNCCNGCNCCNAARGTNGTNTAYTTY GAYACNCCNTTYGGNMGNGTNGGNATGGTNGTNTGYTTYGAYATHYTNTTYAARGAYCCN TCNGTNACNATGGTNACNGARTAYAAYATHACNACNATHGCNYTNCCNAAYGCNTGGTAY GAYTTYYTNCCNYTNGTNACNGCNATHGGNTAYCAYTCNTCNGTNGCNMGNGGNYTNGGN GTNAAYGTNYTNTCNGCNAAYATHCAYATGCCNTCNACNMGNACNTAYGGNAGYGGNATH TAYACNCCNAAYGGNATGTCNTCNTTYTAYTAYAAYAGYAAYCCNCAYTCNACNGGNCAR YTNYTNGTNTCN------------------------------------------------ ------------------ACNATHGAYACNGTNTCNCARCCNMGNYTNYTNGAR------ ---------------------------AARAARGTNAAYACNTCNACNCCNGTNGAYAAR ACN---------------------------ACNAAYGGNAGYGARTTYCARGCNAARYTN TTYGCNGAY---ACNTTYACNTTYMGNYTNYTNGAYGGNACNTCNGGNCAYYTNAAYGTN TGYCARAARAAYGTNTGYTGYTCNYTNACNTAYAGYYTNGCNGAYMGNTCNCAR---TCN GARATGTTYGCNTTYGGNGCNTTYGAYGGNACN------TAYGTNGCNAARGCNTAYTTY CARATHTGYACNYTNGTNAARTGYGCNAARCAYGGN---GAYMGNTCNTCNTGYGGNTCN CARACNTCNGTNTCNACNACNAARTTYAARTCNTTYTCNATGACNGGNCAYTTYCARACN AARTTYGTNAAYCCNCARGTNATHYTNTCNGARGCNGGNCARYTNGCNYTNGCNAAYCAY AAYTCNTGGACNTTYCARGGNACNACNYTNACNTCNCARTCNGGNATHGARGARAARTCN ATHYTNTCNGCNGCNYTNTTYGGNMGNTAYTAYAGYMGNGAY------------------ ------------------------------------------------CARTAYGAYGAY GAYATHTGYMGNGAYTTYATGMGNAAYGTNTGYACNMGNGGNAARMGNTGYMGNTAYMGN CAYCCNGTNGTNGARGARCAYACNGARACNCCNCCNMGNMGNGAYATHACNTTYTGYCAY GAYTAYCARAAYAAYGGNTGYACNMGNCCNAAYTGYAARTTYYTNCAYTGYTCNMGNGAY GARGARGARTGGTTYCAYMGNACNGGNYTNYTNCCNGCNMGNYTNAAYCAYCCNTCNAAY ---CCNTGYAGYGTNATGCAYMGNGCNGARGTNCCNYTNTGYAARGAYTAYATGAAYGGN GAYTGYAARMGNGGNAAYAARTGYMGNTAYMGNCAY---AARTCNGARTAYGAYTAYGAY MGNAAYAGYAGYGGNGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNAAYMGNTAYMGNCCNYTNCCNCCNGCNCCNTCN CCNAGYCCNAAYAAYMGNAAYCARCCNYTNGGNYTNACNGAYCCNTAYAAYAGYYTNTCN MGNGARGCNCARGCNTTYACNGAYMGNATHACNTCNATGGGNTTYYTNMGNGCNMGNGTN GCNMGNGCNGTNGARAARTTYGGNCARGAYGARAARGARGTNYTNGAYCAYYTNTTYGCN GCNGTNYTNYTNATHGARAARAARTAYGCNCCNGTNCAYGTNGARGCNGCNYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AGYACNGTNTCNTTYACNCCNCAYTTYGTNGTNCCNCCNCCNGAYCCN CCNACNYTNATGYTNGAY---GGNGTN---CAYYTNGCNGAYGGNAGYATHGTNAAYGTN ACNGARGGNAAYATGYTNAAYGTNACNTGYCARGTNACNGGNGGNMGNCCNGAYGTNAGY GAYGTNATGYTNGTNTGY---GGNGAYCARAAYAARACNGTNAAYGGNCARGARYTNTCN ATGCAR---YTNYTNATHGGNCARGCNTTYCARCARGTNYTNTGYGTNTGYACNGCNGAY CAYGARTCNGGNTGYTAYGAYAGYGCNGGNCARATHAARYTNAGYGTNYTNTTYYTNCCN ------------------------ATHCARCARMGNTGGMGNAAYYTNMGNACNTGYTTY TCNMGNGARYTNMGNGARCARMGNMGNGAYGCNACNMGNACNCAYGCNMGNAARMGNMGN AARTAYATHTAYTTYGAYCARYTNGTNTTYYTNYTNCCNTTYYTNGAYAAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GTNAGYGGNAAYAARAAYTGYTGGATHATHACNGAYACNMGN TGYATHCCNGGNTGYGARGGNGGNCCNYTNTAYACNAARMGNAAR---CCNGARGCNGAR AGYTAYYTNACNGGNATHATHGCNTCNTCNYTNTGYTGGAARAAYAAYGARTGGATHGGN TTYTCNGTNGCNTGYGGNATHGAYAGYATHATGGAYTCNATHAGYCAR------------ ---CAYCCNGAYTTYTCNMGNAAYMGNATHGAY---GGNAARYTNMGNTCNGTNATG--- ------AARYTNAGYMGNCCNTTYGTNTCNGARCCNGAYGARGGNACNGCNCARGCNGTN ACNGTNYTNATHMGNTGYGGNAGYACNTGGGGNACNGGNGTNATHGTNGAYMGNGAYCAR GGNGTNATHYTNACNTGYAGYCAYGTNATHAARGAYGCNGAYMGNAAYMGNGTNACNGTN ACNCCNTGGAARAGYGAYMGNAARTAYGGNGCNGARGTNATHTAYMGNCARGAYCCNGTN AARGARCCNTAYGAYYTNGCNGTNATHAARTGYCAYGARGCNACN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNGGNTTYCARGTNACNMGNCARATHCCNAAYACNGAR GTNTCNATHTCNMGNGAYTCNYTNCARATHACNAARMGNGGNATGGGNGGNGCNCCNCCN GTNACNTCNATHGGNGAYTCNGTNCCNATHATHCARATHMGNAAYGAYMGNTAYMGNCAR GARATGCARCCNCCNCARCCNACNTGGTCN---------------AAYCARCCNTCNCAR MGNYTNCCNCCNCARCCNGCNCAYGCNGARATGCARTAYTCNCAYCAYMGNCCNTCNTAY TCNGCNCCNAGYMGNCCNTAYTCNTCNCARAAYMGN---TAYCARAAYYTNGAYAAYCCN GARYTNAAY---AGYTCNTCNATHAGYGTNCAYGARATHCCNAARATGCAYATHTCNAAY ATHAARGCNGTNGARGCNGCNGGNATGMGNCCNATHTCNMGNTCNGCNCCNCCNYTNCAR CAY---------------MGNGCNCCNCCNGGNGCNGCNACNYTNTCN------------ GCNAARCARCCNATHACNATGTCNCARCCNTCNTCNGGNAGYYTNAARMGNMGNCAR--- CCNGTN------CARGARGTNGGNGGNCCNYTNMGNYTNGGNAARGGNGGNGGNCCNGGN YTNCARGTNGGNATHGGNGARGGNTCNCCNCCNAARMGNGCNAAR------GCNGGNGCN YTNCCNTCNGARCCNATHGARATHATGGAYYTNGARGAYAAYTCNAARTTYGTNAGYCCN YTNCARGGNTTYMGNGTNGTNGTNACNAAYYTNTTYTCNGGNGTNACNCARGAYGAYATH ATHGARYTNTTYGGNGTNGTNGGNCCNYTNAARAARGCNMGNYTNYTNAARGCNGGNTCN GCNGARGTNGTNTAYACNAGYMGNGARGAYGCNGTNAARGCNGTNCARAARTAYCAYGGN MGNGARYTNGAYGGNCARCCNATGTAYGTNAARATGACNACNCCNTCNACNGCNGTNGTN AARGCNCCNCARGGN---TAYGAYCCNGAYATHACNGGNGARGCNYTNMGNYTNTAYAAR AARCCNAGYAGYYTNGGNGCNYTNCCNGARGGNCCNATHGARGTNCCNACNATHCAYMGN GCNYTNTTYAARGTNGGNCCNCCNGCNCCNAAYAARTCNGTNAARTTYACNGTNAARATH ------ATHCCNGGNTTYATHCAYYTNGTNMGNGARTCNGTNYTNACNCAYGARTGGACN AAYGCNGTNAARATHACNCAYGCNGTNGTNAAYGARGCNCAYAARGTNGCNAAYACNYTN TGGAARGTNGGNYTNACNTCNYTNATHYTNGARAARAARCCNAARGTNGTNGAYCARTAY GTNMGNCAYYTNTAYAARGTNTAYGGNYTNACNTGYACNGARGTNYTNYTNGAYTAYYTN YTNTAYYTNYTNGTNATHGGNGAYYTNGARMGNGCNGARGARYTNYTNCARGARTCNAAR ------TCNTAYTAYGTNTTYGTNMGNAAYGARAARMGNGAYGAYGCNAARATHYTNTTY TCNGGNTAYATGGGNTTYACNCARTAYGTNAARTGGAARACNCARATHGTNCARGARGAR ATGAARGAYMGNGARTCNGAYTTYATHAARTCNATGYTNTCNCARGGNTCNTCNGGNAAR TCNTCNAARYTNACNTCNYTNACNGCNYTNGAYCAYTTYGCNTGYATHAARGGNAARCCN GGNGTNTGGGAYATHTTYATHATHAARATGATHGARATHTAYGARTAYTAYGAYGAYYTN GCNACNGCNMGNAARYTNYTNACNGAYTAYMGNAARGARAAYCCNTGYAAYCCNAAYGCN CAYCAYTAYYTNTTYAARTTYGAYAARAARCAYGARATHGAYACNGARGAYACNATHCAR ATHYTNACNAGYATHGTNAARTCNGAYCCNAGY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARAARTCNTCNGARTGYTCNACNTGYAARGARATHGTNGAYAAYTTYCAYAARGGN YTNTCNGCNACNGARAARTCNAAYTAYGGNGGNGGNAAYACNAARTGGGARGARAARTCN YTNGGNTCNTAYGCNTTYAGYGARGTNMGNYTNGTNGARATHGTNGARAAYYTNTGYAAR GAYAARTCNAARGARTGYCAYACNATGYTNGARGARCAYGARGAYYTNGTNGARAGYTTY TGGTTYAARCARTTYACNAARAARACNAAYAARGAYTTYCAYACNTTYYTNTGYATHGAR AAYATHAARGCNTGYTGYCAYAAYAAYACNTTYGGNAARAAYTGYGARCCNTGYCCNGGN GGNGTNGAYAAYCCNTGYCARGGNAAYGGNAARTGYGAYGGNGARGGNACNMGNGGNGGN ACNGGNAARTGYMGNTGYTCNTCNGGNTAYACNGGNGAYYTNTGYTCNGARTGYAARGAY GGNTAYTTYGARGAYAGYAARAAYGAYTCNCAYACNGTNTGYAARGTNTGYCAYATHTCN TGYAARGAYAGYTGYGAYGGNTAYGGNCCNAARGCNTGYGAYGARTGYAARGAYGGNTGG GTNGTNAGYGARGARGAYGGNTGYCARGAYATHAAYGARTGYYTNGARGARCCNTGYGAR GAYGAYCARTAYTGYATHAAYACNCARGGNTCNCAYTCNTGYTTYAGYTGYCAYTCNGCN TGYACNTCNTGYACNGGNTCNGGNCCNGAYAARTGYAAYGARTGYAARGARGGNTAYGCN MGNYTNGARAAYGGNAAR---TGYGAYGAYAARGAYGARTGYGTNYTNGAYCCNAGYYTN TGYCCNAARGAYAAYGARGARTGYACNAAYACNCCNGGNAGYTAYCARTGYATHTGYTCN ACNGGNTAY---GARTAYAARGAYGGNGARTGYTTYAARGCNCCNGARNNNMGNTCNAAR YTNGTNAAR------ACNGARGARATHAARTTYGCNAAYAAYYTNAARATGGGNGGNTCN CARAGYAARMGNMGNYTNGTNGTNGARGAYGTNAAYGGNGARGGNGTNGTNCARGTNACN GAR---GCNGTNGTNMGNMGNGTNAARGGNCCNGAYTCNCCNGTNCARAARTCNTCNGAY GARTCNAARATHGAYAAYGARAARTAY--------------------------------- ---------CARGCNATGAGYAARGARATHGARGAYTTYTAYATGGARAARYTNAAYGAY YTNCARGAYMGNAGYCARGCNYTNCARCARCAYTCNAAYGAYCARTTYGCNAAYGCNGTN AARGARGTNGARCARAARTTYATGAARTAYACNTCNTCNCCNGTNTGYCARGAYYTNCAR ACNAARGTNYTNCARTGYTAYCARACNAGYCCNGAYTCNATHYTNGAYTGYTCNGCNYTN GTNACNGCNTTYTCNACNTGYGTNGAYMGNGCNMGNATGACNGTNTCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGGNGCNATG YTNGTNTCNACNGGNAAYTAYGTNGARGGNYTNGCNTAYYTNAAYAARGCNATHCCNCCN GARGGNAARMGNGAYGGNMGNTCNAAYGGNGAYYTNTAYTTYAAYTAYGGNATHGCNTAY GARGGNYTNAARAAYGTNGCNAARGCNMGNAAYTAYTAYGARACNGCNYTNAARGARTAY MGNGCNGARCAYGAYAAYGTNAAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GARGGNGAYTCNGAY GAYCCNGTNGCNAAYATGACNMGNGAYGTNTGYGCNGAYATGYTNGARTCNATHCARAAR YTNAARGARYTNGARCCNGAYAAYCCNAAYATGAARMGNATHATHGARATGCARGARCAR YTNAAYGCNYTNCARAGYTCNYTNAARAARACNYTNCCNAARATHGCNGAYCCNGAYAAR GTNTCNGARGCNGAYGAYAAYTCNAAYYTNAARGAYTCN--------------------- ------AARMGNGTNAGYCAYAGYGARAARAARCARAARGARATGGARGCNYTNGARMGN ATGATGGARGARACNGAYMGNGCNGARMGNCARMGNGARGARGAYYTNMGNCARCARMGN GARATGGARATHCARAARGCNMGNGARTAYGARGCNAARMGNAARTCNCARTGGGCNMGN AARATHATHYTNGAYTAYAARCARGAYGGN------------GTNAARGAYATGGGNGTN GGNCCNGARGGNGARMGNYTNYTNAARCARMGNGARCARMGNATHCAR------------ ---GARMGNGCNGARGARGARMGNMGNAARGARGARGARAAYYTNMGNYTNYTNCARCAR GARAARGAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGNMGNMGNGARTTYTAYCARAARACNAARCARGAYCCN ACNCARTTYYTNMGNATGTAYGGNMGNCCNTAYAARATHCAYYTNGAYCCNGCNGTNGCN ATHGCNGCNGARGGNCCNCARAGYATGATGTCNTGGCARGGNGAYAGYTCNAAYATGATH GAYMGNTTYGAYGTNMGNGCNAAYYTNGAYTTYATHTCNGARCAYAAYCCNCAYGGNTCN TCN------AGYACNTCNAAYGTNGAYGARGARGARMGNYTNGCNAGYTAYGARMGNTAY MGNACNYTNGTNGARAAYGARGCNGCNGGNYTNACNGARGARCARAGYYTNCAYCARATH TAYYTNGAYGARCAYTTYGGNACNATHGAYAARTCNAAYGARGARGARAARAARAARAAY GCNGAYAARAARGCNGCNATHGGNTAYGTNTAYGARGAYAGYACNCCNGTNGARAARAAR GARCCNGARGARGARAGYGARGARGARAGYGAYGARGAYYTNGAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNYTNTTYGCNGTNYTNAAR YTNGAYYTNTTYGAYAARATHMGNAGYGARATGGGNGARTGYYTNGTNGAYYTNAARGAR YTNGARGGNMGNYTNGARCARGGNCARAARTCNCCNAARACNAARCARGARATHGAR--- ------------------------------GARATGGCNACNTCNTAYCARMGNATHMGN TCNTGYYTNGARGARGCNGTNMGNATHATHTCNYTNGCNTGGATHACNGARYTNCCNCCN ATGGAYAAYCARGGNAAYTTYCAYAAYCCNGARYTNGTNGARGARAAYGAYAGYYTNAAR TCNGARYTNATHMGNYTNMGNAGYMGNTGYGAYGTNYTNGAYYTNGCNGTNAARAGYCAY CARGGNMGNYTNGARGCNTCNACNCARMGNCAYMGNAAYTGGGARGARGCNGTNTAYMGN CAR---------AARGGNAARMGNTCNMGNAGYYTNTCNGARTCNTTYGAYGAYTTYAAY AGYATHGARGARAAR---------------GAYACNGTN------------GAY------ ------MGNGARATGGARACNGARMGNAAYYTNCARMGNAAYAAYAGYAARATHYTNAAY CCNGARYTNTGYGTNCARTAYGAYCARATHAARMGNTCNTAYGCNAAYATHYTNTAYAAR TGGGGNYTNYTNAAYCARMGNACNCARGTNYTNAARCAYACNGTNTCNGTNCARGCN--- GAYAARAARATHGARTTYTCNATHCCNTGYTCNAAYTGYAAYGAYAAYGGNATGCAYGTN CARTGYAAYMGNTGYMGNTAYCCNTCNYTNAAYTGYTCNATHTGYCAYGTNGGNGTNMGN GGNCCNGCNAAYGTNTGYYTNGCNTGYGGNCAYGGNGGNCAYTCNAGYCAYATGATGAAY TGGTTYCAYAGYAAYAGYCARTGYCCNTCNGGNTGYGGNTGYATHTGYGTNCARGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AAYAGYAARYTNYTNGARMGNATHTCNMGNGTNGARGARYTNGARMGNGGN ATHGARAAYYTNCAYAARGAYGTNGARMGNMGNATGATGMGNGTNGAYGARCARYTNAAR AARTAYGARACNGARYTNGTNGAYMGNGTNCARGARATHGGNGAYYTNAARGARAAYGTN AAYACNTGYCARYTNAAYYTNGCNGARAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GGNTAYGAYGGNTAYGGNMGNGGNAAY GGNGGNGAYAGYTAYTAYGGNTAYAAYAAYGGNGGNAAYGARGGNGGNTAYGGNGGNCAR GGNCARGGNTAYGARAAYCARGGNGARAGYTAYGGNAAYAGYGGNGGNGGNTAYGGNGAY AGYGGNCAYGAYAGYGGNCARAGYAARGGNYTNCAYGTNCCNAAYGARGTNAAYTAYGGN CAYTCNTAYACNAARTCNCCNATGATHTCNTTYGTNAARGGNTTYAARCCNGGNAARACN TAYGTNGAYAARGGNTAYGTNATHMGNAAYTAYTTYMGNCAYGGNACNTAYGAYGTNGCN GTNCARCAYTAYAARYTNGTNCCNATGGTNAARGTNATHCCNTAYACNACNCAYCARAAR ATHGCNGTNGGNCARAARGTNGARGCNMGNTTYMGNTAYAARGCNTAYATHTGYAARTAY TGYTAYCAYGGNTAYCCNAARATHGAYATHTAYGARATGAARAARCCNTAYAGYTTYACN GTNMGNMGNTTYGTNTTYYTNCCNAARGAYTAYAARYTNGAYGGNTAYGGNAAYGAYTAY ATHAAYGGNAAYGGNAAYYTNCAYGGNAGYGGNCAYCARCAYGGNAAYGCNTAYMGNAAY GGNAAYGCNTAYCARAAYMGNAAYGGNTAY------------------------------ ------------------------------CAYACNGARTCNCARGCNAGYGAYAGYAAR GCNYTNGCNGTNGTNYTNTAYAARGARGARACNYTNYTNCCNCAYGARAARAARCAYMGN ACNTTYCAYATHGCNGGNCAYAAYTTYCAYATHGARCARGAYTGGCAYYTNGGNGGNGTN GCNGCNGTNGTNTGGGAYGCNGCNGTNGTNYTNGGNGARTTYYTNGCNTCNAAYAARTTY CCNGTNAARAAYAARMGNGTNYTNGARYTNGGNGCNGGNACNGGNYTNGCNGGNATGGTN GCNTCNYTNYTNGGNGCNGAYGTNATHGTNACNGARMGNCARGARGCNYTNTCNTAYYTN GARTCNGCNGTNTCNAARAAYYTNGTNGGNATGGAYTGGAARATHAARGCNGARGTNYTN GAYTGG------ACNYTNAAYGTNGAYTCNAAYATHTGGGCNGGNTTYGAYYTNGTNATH GGNGCNGAYATHATHTAYATHGARAGYACNTTYTCNCAYYTNYTNAARACNYTNAARTCN GTNGCNGCNACNTCNAARACNCARGTNYTNYTNTCNTGYMGNATHMGNTAYGAYMGNGAY YTNAARTTYYTNCAYATGYTNAARAARTTYTTYAGYGTNGARGARATHTTYTAYAAYGCN GARYTNGAYATHAARATHTTYTCNGCNATHTCNAARCARYTNGTNACNCAYTTYGGNGGN TGYCAYTGYGGNGCNGTNMGNTTYTCNGTNCARGCNACNCCNCAYYTNGAYATHGTNGTN TGYAAYTGYAGYATHTGYACNAARAARCARAAYCARCAYTTYATHGTNCCNAARTCNAAR TTYAARYTNYTNCARGGNGARGAYTCNYTNACNACNTAYAGYTTYAAYACNCAYGTNGCN AARCAYACNTTYTGYAARACNTGYGGNGTNCARAGYTTYTAYAGYCCNMGNTCNAAYCCN GAYGGNTTYGGNATHATGCCNCAYTGYYTNGAYGARGGNACNGTNACNTCNAGYAARGTN GTNACNTTYGAYGGNAAYGARTGGGARAARTCNTTYCARACNTCNAAYATHACNGARTAY TCNAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNTCNTGYTCNGTNTGYCARTGYMGNACNGARACNMGNAAY ACNACNACNATHAARGTNGTNGTNATHTTYATHATHTGYGTNGTNTCNYTNYTNTTYGTN TAYATGYTNTTYYTNYTNTGYYTNGAYCCNYTNYTNCARMGNMGNCCNGCNAARTCNTAY CARCARCAYACNAAYGARGARGTNAAYYTNGARGARGAYTTYTCNTCNGCNMGNCCNGAR GAR------------GARCCNGARGCNGCNGGNCCNTCNACNGARGCNATGTCNGCNMGN CARMGNTCNYTNYTNAAYATHGTNACNAARGARCARAARAARTGGAARGGNACNGTNCAR GARCARMGNMGNAAYATHTAYGAYMGNCAYTCNATGYTNAAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNGAR AARGCNCARTCNAARGARGARAAYGTNATHATHGCNTCNCAYATHGGNTAYCAYTGYACN TTYCCNAARGAYTAYGCNATHTGYYTNTCNTGGAGYTAYCARGARGTNATGGAYATHGTN CAYCARTAYGGNTGYGTNGTNAGYGTNTTYGCNGGNCAYGARCAYAGYGGNTCNCARTAY YTNGAYGAYTAYGGNGTNCARCAYATHAAYTTYCARGCNGTNYTNGARACNGCNCCNGGN AGYGAYGCNTAYGCNACNGCNAAYYTNTGGGAYAARGARYTNACNATHTCNGGNGTNGGN MGNGTNCCNAGYTTYACNATHGCNYTNMGNTAYCCNMGNYTNACNGAYYTNYTNAAYGAY TGGACNAAYAARTTYCAYGCNGARGGNATHTCNGAYTCNTCNTCNAGYGCNGARTAYATH ATHGCNTTYGTNYTNGGNMGNAARACNYTNCAYAAYGTNAAYAARAAYGAYTTYATHYTN GAYGARGAYGAYGTNGCNTCNGTNCAYGARYTNTGYMGNYTNMGNYTNAARMGNATGCCN GTNCARTAYGTNATHGGNCARTGGGAYTTYCARGAYYTNACNYTNAARATGMGNCCNCCN GTNTTYATHCCNMGNCCNGARACNGARGARYTNGTNAAYCAYTGYAARCAYATHYTNGAR TCNAAY------TGGTCNCARTGYGARCARCAYCCNGTNTTYYTNGARGTNGGNTGYGGN AGYGGNGCNATHAGYYTNGCNYTNYTNAARCAYTTYAARCARYTNCARTCNATHTGYGTN GARATHTCNCCNAARGCNTGYGCNYTNACNATGGAYAAYGCNAARGAYGTNGGNGTNGAR GAYMGNYTNCAYGTNYTNAAYGARGAYTTYACNAARCAYGARGCNTCNTCNAARYTNCAR GCNATGGGNCCNTAYTGYYTNYTNGTNAGYAAYCCNCCNTAYGTNACNGCNAARGARATG GARAGYYTNTCNTCNGARATHTCNMGNTTYGARGAYCCNGTNGCNYTNGAYGGNGGNCAR GAYGGNYTNGAYYTNGTNMGNCAYATHYTNYTNCAYGCNCCNCAYYTNYTNATGCCNCAR GGNCAYYTNYTNYTNGARGTNGGNGARGAYCAYCCNMGNGCNATHAARGAYTAYGTNACN ACN---AAYAARGCNYTNGGNYTNCARTTYGTNGARTCNATHCARGAYATGTTYGARMGN GAYMGNTTYTGYCAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------MGNYTN GARGCNAARYTNCCNGTNAAYYTNACNGCNAARCAYTCN---CAYCCNATHTAYATGGAR CCNAARGCNCCNTCNCCNCARCCNCCNAAYMGNCCNGGNTCNGCNMGNGTNCCNMGNTCN AGYTCNGCNMGNCCNGGNTCNTCNAAYTCNCARCARMGNGCNCARTCNACNATGCCNACN MGNGTNGARGAYGCNGTNCCNGTNCCNCARAAYAGYCARATHGGNGGNTCNMGNGCNACN ACNCCNYTNCARGAR---GCNGARGTNGTNYTNAAYYTNGTNGCNGARGARAAYGAYCCN CARGARCARGCNCARAARGARGGNATGATGCARGARCARGAYGARGCNATGTTYAARMGN CCNAARCCNAARGTNYTNCARAAYGGNAGYMGNGARTCNGTNGAYAGYCARYTNAGYACN TCNAGYGCNAGYAAYGARAAYYTNGCNCCNAAYACNAARGARACNAARGAYACNGTNGAY AARATHYTNCAYCARMGNGTNCAYTTYCARGTNTAYTAYYTNGGNYTNGTNCCNGAYATH AAYYTNACNAAYTCNMGNAARMGNGAYACNGARGCNCARYTNATHGAYGTNGTNGARGAR AAYCARATHGAYGGNAARYTNCARGTNACNGCNACNGAYGARAAYAARGTNGTNATGAAY GTNTCNMGNCAYGGNATHAARGTNYTNGAYATHGCNGGNAARGARGTNYTNCARMGNCAY CCNYTNCAYACNATHGCNCARGTNACNGARTAYAAYGAYGGNTTYGGNMGNCARAAYATH GCNGTNAARATHGGNCARGTNGGNAARAAYGTNTAYCARTGYTAYGTNTTYCARTGYCAY TCNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GGNTAYAAYTTYMGNYTNAAY GTNTCNATGACNGARCAYYTNCCNGTNACNGGNATGCCNYTNMGNATHGTNATHATHGTN TCNTTY------------------------------------------------------ ------------------------------------------------------------ ------GAYMGNGTNMGNYTNGCNMGNMGNGARAARGARATHTCNTAYGGNAARAAYACN GAYTCNTAYAARYTNTAYATHAARGTNGTNCCNAARGARGARMGNGTNGGNAAYYTNAAR ATHCAYCCNMGNACNCCNACNAARATGACNAARTGYAGYMGNMGNAAYTGGGAYGCNCAR ATHAARGCNTGGAARAARCAYGTNCAYGARTGGGCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AARTCNCARMGNGARGGNMGN TCNAARAARMGNAAYAGYGGNMGNGGNTAYAGYTCNTCNGARTAYTCNTCNCAYTCNMGN TCNTAYTCNMGNTCNMGNTCNGGNTCNTAYMGNAGYTAYACNGAYGAYTCNMGNTAYAGY GAYTCNAGYMGNTCNCAYAGYMGNTCNTCNMGNAGYTAYAGYMGNAGYMGNTCNMGNCAY MGNTAYMGNMGNMGNTCNTCNTCNAGYMGNGGNMGNAGYMGNAGYTAYAGYTAYAGYAGY MGNAGYAGYTCNAGYMGNTTYMGNTCNMGNTCNTAYTCNMGNTCNMGNAGYTAYACNMGN TCNMGNTCNMGNACNMGNACNTAYCAYAGYACN---TCNMGNAGYCCN---TCNMGNMGN AGYATHAARYTNAARMGNATHYTNAARTCNCCNYTNAGYATHGTNCCNGTNACNACNYTN ACNGTNGCNCCNGTNACNGGNTGYACNATHGGNGGNAARGAYAAYAGYGCNAGYGGNAGY GGNGGNGGNGARGGNAGYGGNACNGGNGGNGGNCCNCCNGAYGAYATHCCNYTNCCNGGN AARGARGCNCCNGCNGCNGCNACNGCNGTNGCNGCNACNAGYCCNAARAARGAYAARGCN GTNYTNACNGAYATHCCNYTNCCN------------------------------------ ------------------------------------ACNTCNTCNACNGTNGGNAARGAR ACNAAYTGYGCNGARACNCCNGCNGCNACNGGNGAYGGNGCNAAYCCNACNCCNGCNCCN GAYCCNGCNCCNAAYCARCCNAAYGGNAAYAAYGAYYTNGGNAAYCCNGCNGGNGARGAR MGNCCNGTNGARACNAGYYTNCCNGAYGARATGGGNATGGCNAAYCCNGARGAYGTNYTN GGNTAYGAYCARGAYTCNTTYGGNCAYYTNGCNTAYGGNAAYCAYGAYGCNGCNTTYTGY GARGAYACNGGNTAYGAYAGYTTYGARTTYGAYGGNGAYTAYGAY---CARCAR------ ---GGNTAYGARGAR------CARGARTAYGAYTAYCAYCCNGAYCCNTAYCAYCAYCCN CCNYTNMGNCAYCARGGNCCNCCNCAYGGNCAYCAYATGMGNGGNCCNCCNCCNCAYGGN TAYMGNGGNCCNCAYCCNMGNATGTTYCCNCCNGAYCCNMGNTTYGGNCCNCCNMGNCCN GGNATGGGN---CCN------------------CCNMGNATGMGNCCNAAYGGNCCNATG GGNCCNMGNGGNCCNMGNCCNCCNATGGGNCCNGGNGGNCCNATHGGNCCNCCNGGNATG MGNGGN---CCNCCNMGNGGN---CCNCCNMGNGGNCCNCCNGGNATGMGNGGNCCNCCN GGNATGCCNGGNCCNMGNGGN---CCNCCNMGNCCNGGNATGATGGGNCCNCAR------ GGNCCNATGGGNCCNAAYGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNTAYYTNTGGGAYMGNMGNYTNAAYATHAARGAYTTYATHGARGCNATHMGN CARCARGARTGYGAYATGGAYMGNCARYTNYTNGCNGAYGARCCNGTNCCNYTNYTNGAR AAYGCNTCNTCNGAYGTNMGNAARYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MGNGCNATHTTYTTY MGNATHATHGAYYTNYTNAARAARGGNATHACNGCNGTNTAYGTNTTYGAYAGYAARGAR GCNATHCARYTNAARMGNMGNAARMGNGGNGARAARTTYTTYAARTGGAAYTCNAARTGG AARYTNYTNYTNGARGCNATGGGNTTYCCNGTNATHMGNTCNGGNGGNGARGCNGARAAR ACNTGYGCNTAYYTNTCNAARAAYAARATHGTNGAYGGNTGYATHACNACNGAYGGNGAY GCNYTNGCNTAYGGNGCNACNACNATHYTNAARGGN---------TAYAAYGTNAARAAY AARATGATHGAYGTNTAYGARATGACNGAYATHGTNGCNCARYTNAARYTNAGYCARMGN GARATGATHGCNGCNGCNYTNGTNYTNGGNTGYGAYTAYGGNGARGGNGTNGCNAAYATH GGNCCNAARAARTTYYTNGARTTYGTNCAYGARYTNCARAGYCARAARGTN---GAYATH YTNGAYMGNATHMGNTCNTGGMGNCARGAYGAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARYTNMGNCAYGARGTNAARYTNYTNGAYYTNGAYMGNCARMGNCAYACNGTNGARGTN AARAARMGNYTNGARCCNAARAARGAYTAYGGNTAYGAYGARGTNCARATHCAYAAYACN GARMGNMGNYTNGGNGCNAAYATHGCNTCNTTYTAYYTNGAYAARAARYTNAARTAYCCN ATGMGNYTNMGNTCNGTNAARGAYATHMGNGTNACNCCNACNATHTCNMGNGCNMGNGCN AARATHMGNTCNACNGAYYTNACNMGNCAYATGGARGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARAARTTYAARTCNGAYTAYCARGCNYTNAARAARMGNYTNAAR ACNYTNCCNGAYAARYTNTCNCAYGAYGTNATGGTNCCNTTYGGNAARYTNGCNTTYATG CCNGGNCARATHGTNCAYACNAAYGARGTNYTNGTNYTNYTNGGNGAYAAYTGGTTYGCN GARMGNTCNGCNAARCARGCNTGYGAYATHGCNAGYMGNMGNATHAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNCCNCCNAARYTNMGNAAR YTNGCNATGGARAAYGCNGGNYTNYTNTAYTAYYTNACNMGNYTNTCNGTNAAYGARACN AAYCARYTNGARGARYTNCAYYTNGCNTCNAAYGCNTTYCCNATHGTNGARGGNCCNTTY MGNGGNTTYAAYMGNYTNAARATGYTNGAYYTNGCNCAYTCNCARATHTTYAAYATHGAR GARACNTTYTTYAARCAYTTYCCNTCNYTNGARCAYYTNGAYYTNTAYGGNAAYTTYYTN ---GGNTTYGGNACNAGYYTNAGYCAYCAYCAYCCNTTYAARTAYYTNACNAARYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AGYMGNAGYGCNYTNTCNGTNGTNYTNGCNATHYTNCAR AAYYTNGCNYTNGCNGCNGCNGGNACNATHGTNCCNTCNGCNYTNGGNGCNGTNTAYYTN YTNGCNTTYYTNATHATHYTNACNYTNTGGGCNTGYTAYAARACNYTNGGNGCNGCNTAY GGNTTYGTNMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYATHGTNATHGGNTAYCAYGARGAYGAYATHGAR TTYGTNAARMGNYTNGCNAAYAARYTNMGNACNAARGGNYTNAGYGTNTGGTAYAAYGAR CCNGGNGARGAYGGNAARAARACNAGYGARGCNATHYTNGGNTGYAARGTNTAYYTNCCN GTNYTNACNGARTGYTCNGCNGTNGAYAARAAYATHCAYGARCARYTNNNNYTNGCNTAY ATHTCNAAYTCNGCNATHTAYCCNYTNGGNMGNGTNMGNTTYGGNYTNYTNGCNCCNAAR YTNAAYGGNGGNGCNMGNYTNATGYTNGCNAARATHAAYTGGTCNTTYATHTTYAARGAY ACNGAYTTYGARGARAARATGGARACNATHATHGTNTGYATHCARAARGAYYTNAAYAAY ATH---MGNACNGARGARGCNCCNCAYGAYGAYTCNGGNTAYGTNCAYACNCAYGGN--- ---ATGCCNGTNAGYATGAAYCAYGTNCCNGCNATGGGNGAYAGYGARCCNGAYTTYGTN ACNTTYATHCARGGNATHGAYYTNTCNTCNATHAGYCARGAYACNCCNTTYTGGGAYMGN CAYTTYAARGGNAARACNGARGTNACNTGGATHCARTTYMGNGAYCARTTYYTNAARGAY TAYGGNCCNAARATHGTNGARGGNTTYTCNAGYAGYGARGARGARMGNAARAARYTNTTY GTNAAYYTNATGTAYAARGAYGTNTTYGTNYTNAAYAARAAYATHAARMGNTCNGTNTAY GAYAARTTYTGYGGNAARCCNCAYCCNCAYGCNTTYTTYACNGGNATHCARGAYTAYGTN ATGGCNTAYTCNTCNYTNMGNGARGTNYTNGGNATGGAYAGYAGYYTNMGNATHCCNACN ATHCARAAYYTNGGNMGNTTYCCNTTYCCNGCNATHGTNTCNGGNYTNTCNGAYATGYTN ATGGAYGAYGAYCCNAAYATHMGNGCNGTNGCNGCNATHGCNYTNGCNCAYGCNGGNAAR AARAARGARTCNACNGTNGAYAARATHATHAARYTNYTNGARGAYGARGAYMGNYTNGTN MGNGARAGYGCNTGYYTNAGYYTNGGNTAYYTNMGNTCNGCNMGNGCNGTNACNCAYGTN GTNGAYMGNTGGMGNAAYGAYCCNATHTCNACNGTNMGNGARGCNGCNGARYTNGCNYTN AGYMGNATGGAYGCNCCNGAYGCNGTNCARTGYATGAARGTNACNAARGTNYTNTCNTCN GARATGAAYGCNYTNAARCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHGAR GAYGTNGARAARCARATHCARMGNMGNGARAARGARYTNGAYGARATHGARMGNCARTGY MGNYTNGTNGARATGTCNGAYGTNAARMGNCARGARYTNACNTCNGARAARAARYTNYTN GARAARCARATHAARAARTAYMGNACNGARYTNMGNGGNYTNMGNTGGCARAAYTGGAAR AGYATGYTNATHTCNGTNTGYYTNTTYGGNYTNYTNTAYATHATHTAYYTNYTNTTYTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MGNCAYGGN GGNAARGCNMGNAARGGNGAYGGNAAYGARGTNTCNCCNAAYCCNCAYAARYTNTTYAAR ATHGGNCAYCARYTNYTNMGNYTNAAYAARAARATHAAYGCNTGYCARYTNGGNTCNGAY GTNCCNYTNGCNAARMGNAAYGARTCNMGNAARGARAARAAYAARYTNGCNTCNMGNGCN TGYMGNYTNAARAARAARGCNCARCAYGARGCNAAYAARATHAARYTNCAYGGNYTNGAR ATGGARCAYGGNCARATHAAYAAYGTNYTNMGNYTNYTNTGGCCNGARYTNMGNGARMGN GCNAAR---------TCNYTNATGAAYAARAARGCNGTNGAYGARAARGAYCAYCCNGAR AAYAGYTTYACNAAYAARYTNACNGGNTAYATHTCNACNAAYYTNAARAGYATGGTNGCN GGNAAYACNACNGAYTAYGTNAAYAAYATHATHATGGCNGTNGARMGNGGNGAYYTNAGY GGNGGNYTNAARATH---AARTCNAARAARACNAGYMGNMGNTCNGCNACNCCNAAYTCN GTNMGNAAYATHGARAAYATHCCNMGNMGNAAYGCNMGNAARTCNTCNGTNATHAGYGTN AGYGAYGARGGNACNGCNGTNGGNMGNGAYYTNGARYTNGCNYTNGCNTAYAARGTNGAR AARCCNGTNYTNTCNGCNAARGCNTCNMGNATHYTNAAYGARYTNGTNATHGARAARGTN GAYGGNGARAARAGYTTYTTYGARGTNTCNTTYGAYGARTCNATGTTYAGYTAYCCNGAR TCNAARTCNGTNAAYYTNTCNTCNTCNAGYAARATHCARTCNACNTCNACNTCNCCNTTY ACNCCNMGNAARTCNAAYGARGTNACNAGYAGYAGYAGYTCNAAYTCN------------ ---YTNGTNACNCCNAARACNACNTCNCAYGCNMGNCAYTCNATGGCNCCN---YTNTCN GGNTTYAARGARCCNGGNYTNCCNYTNTCNGCNYTNMGN---AARAGYGGNTCNMGNMGN AARACNACNCCN---------TCNAARACNCCNGARCARATGATHAAYATHYTNAARAAR AGYCCNATGGTNGARATGACNMGNMGNMGNTCNMGNCAYGTNTCNTCNCCNGCN---CCN GTNAARGGNCARTAYTTYMGNGAYYTNATHAAYAAYGARATGGAYMGNYTNACNAAYYTN AGYAAYAARTGGAAYGAYGTNGTNACNMGNGARGCNGGNATHGARGARGAYGTNYTNGGN CARATHMGNTGYACNGTNGGNAARGCNYTNYTNYTNATGGAYCARMGNTTYAARCARTTY TCNGGNYTNGTNGAYAAYTAYGTNTAYGAYYTNGGNGARAARAARACNACNCCNACNGAY YTNCARGGNTTYTGGGAYATGATHTAYTTYCARGTNGARGAYGTNGAYTCNCARTTYAAR GARYTNGARGARATGMGNCARTCNAAYTGGCARATHAARAARGCNTCNCCN--------- ---------ACNGTNGCNGCNGGNCCNAARAARAAR---ATHGCNAAYAARGCNAARGCN AARCCNAARTCNAAYTTYGCNGCNTTYMGNGCNGARYTNCARAARAARAARGCN------ ------------------GARGAYYTNAARAARATGAARGTNCCNGARYTNAARCARGCN YTNAARGARAARGGNYTNTCNATHACNGGNACNAARCCNGAYYTNATHAARMGNYTNATH GARTCNGCNGGNTCNTCNGTNGAYAGYAGY---GAYCCNGTNYTNGAYGAR--------- ------GAYGARATHYTNAARGAYGAY--------------------------------- ------CCNAGYCCNTCNGCNCCNGCNGTNCCNCCNAARTCNCCNACNAARYTNCCNACN GARAARTCNGAYAAYGCNACNAAYGGNGTNTCN---AARAGYACNGARCCNACNCCN--- ------AAYGTNCCNGCNGAYACNACNATHACNGCNAARCCNGARGCNCARAARYTNACN GARGCNGARMGNYTNAARYTNMGNGCNGAYAARTTYGGNATHACNTCNGARCARGCNAAR AARGAYYTNMGNGCNCARMGNTTYGGNATHTCNYTNAGYGARAAYAARTCNTCNGGNAAY ATHAGYTCNGAYGCNCCNATHGAYGTNGARAARYTNAARAARMGNGCNGARMGNTTYGGN GTN------------TCNACNAGYTCNGTNACNGARGAYGARMGNAARMGNAARMGNGCN GARMGNTTYGGNGCNACNYTNACNACNACNACN---------ACNGCNAARTCNGGNGTN ACNACNAGYGAYYTNGARGCNAARAARMGNAARMGNGCNGARMGNTTYGGNYTNGCNACN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CARATHTCNTAYCARTAY---GGNGTNAARCAYGCNAARGARGCNATGTCNTGYGAY MGNYTNAGYGAYYTNGAYATHTCNCAYYTNCCNGAYGGNYTNCARYTNGARATHMGNCAY TTYGCNACNTGYYTNGAYGGNYTNTTYCARTCNATGAGYGTNAARGARGAYATHTAYTCN ATHGGNTGYYTNAGYMGNATHGTNGCNACNGARYTNGAYAGYTTYCCNCCNGCNMGNGCN MGNMGNAARGCNTGYCARTCNMGNATGTCNYTNATHYTNGTNGAYMGNAGYYTNGAYYTN GCNTCNTCNATHACNMGNCARATGGAYGTNYTNYTNGAYAARATGGTNAAYACNYTNCCN GCNYTNAGYGGNCAYCAYACNGAYMGNMGNGTNGAYATGAGYAAYYTNTGYCAYTGYTAY AAYACNAARAGYGGNCARGGNGTNATHYTNCCNGGNTGYYTNGCNCCNTCNMGNYTNGAY GAYTTYCCNTCNCAYYTNGCNTCNAGYGTNACNAARAARCARAARGARGGNYTNATGGAY GTNAAYMGNAARYTNGTNGARACNGCNACNTCNGCNGARYTNCCNYTNGAYYTNTCNYTN MGNCCNGGNMGNATHTCNGCNGAYCARYTNGARTCNACNYTNGCNYTNTTYAARGGNAAR TAYTCNYTNATHYTNAARCAYATGGARACNYTNCARGTNGCNYTNGCNACNAGYCARACN YTNACNGAYCCNTCNATHMGNCAYCAYGAYAAYGTNYTNGCNAARGARAARAGYATGATH CARGCNATHGCNGAYTCN------------------GAR---------------GGNGGN GAYGCNTAYCCNTCNGCNTTYGCNYTNYTNTCNAARATGYTNYTNTCNGARATGGARAAR AGYTAYGAYGARMGNGARYTNACNYTNGAYGAYATHYTNCAYYTNYTNGTNTAYGTNTAY TCNYTNTCNGAYGGNAGYAGYGARAAYCAYGAYGARGTNMGNYTNYTNCARGAYCARYTN GTNCARGTNATHGCNAARGAYAARTCNTGYYTNCCNCCNYTNGTNCARTCNATHGTNGGN GARAARGTNACNGARGCNATHYTNCCNGAYYTNGTNGARAGYATGTGGGAYAARYTNGAY GCNYTNATGGAYGCNMGNMGNGAYYTNAARGAYTTYGGNAAYYTNGTNGAYCCNGGNGGN GCNATGAGYCCNGCNTCNGTNAARCCNYTNYTNAARCARGTNATGGARAARATHGTNGAY CCNGCNMGNCCNGARYTNCCNGAYATHGARTGYAARTCNGGNGGNYTNAARGAYYTNYTN AARTCNGGNTTYGGNTTYTTYAARAGYTCNGCNAARCCNMGNCCNGGNGAYGCNCCNYTN YTNATGATHTTYGTNATHGGNGGNGTNACNGCNTCNGARGTNAARCARGTNAARGAYATH GTNAAYAGYGCNAARCCNGGNTTYGARGTNGTNGTNGGNGGNACNMGNATHTCNAGYATH GARTCNACNYTNAARGCNGTNYTNGTNAAYGAYAAYATHAAYGTN---ATGYTNAARGCN GCNYTNAARACNAGYGAYTGGATHAARYTNGAYACNTGGGARTGYGARCARAGYAGYTGG ACNGARTCNATHAARGTNYTNMGNCAYTGYAARCARATGGTNGARACNCARTAY------ GGNGTNAARCCNTCNCCNAAYAARMGNMGNAARAARCARCARGTNTCNGAYYTNGCNCAY AAYAARATGCCNAARGTNGARGTNGARGARGAYCARGTNCCNGTNGTNAARTTYYTNTGY GGNGCNGAYYTNYTNGARTCNTTYGCNGTNCCNGGNYTNTGGAARGAYGARGAYGTNGAR CARATHGTNGCNAAYCAYGGNYTNATHGTNGTNAAYMGNGARGGNTCNAAYGCNGAYAAR TTYGTNTAYGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGYTNAARATHGTNAARGTNYTNGARAAYCCNGTNTTYCAYTTYAARGCN YTNAAYGTNATGGGNMGNYTNYTNYTNYTNGTNACNGCNGGNTGYYTNTAYAARCAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GTNACNATHATHAAYYTNGARCAY YTNGTNTGYTGYYTNTGYGAYATHGGNGAYCCNMGNYTNYTNTGGTCNGTNAGYGARAAR TTYYTNAGYCARTTYGARGTNAAYATHTCNYTNTGYMGNTAYMGNCCNTTYAGYYTNTAY CCNATGAARTTYGTNCAYGAYYTNAGYTTYTGGGARMGNGARGAYTCN---GARCCNTTY GAYGARTCNGGNYTNTAYGARGCNATHMGNAAYATHGCNGGNGAYYTNGTNATHAAYGTN AGYYTNATHGAYATHTAYAARGARCCNGAYTCNAAYMGNMGNAGYMGNTGYTAYMGNYTN TAYTTYYTNTCNYTNGAYAARTGYYTNCCNTAYGTNATHTCNTGGAARYTNCARAGYMGN ATHMGNATGGARGTNGCNMGNAGYYTNTGYGTNGARYTNMGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GTNGCNTAYATGMGNGGNGGNTGG GAYTCNAAYCCNYTNMGNYTNAARGGNTTYATGYTNAGYGGNTGYTTYATHCARYTNGCN GGNATHTGYGGNTTYGTNGCNTAYYTNGTNYTNGCNATHTCNCARAAYCARAARGTNGAY GCNTAYGGNCARGGNTTYTAYYTNTGYTGYGTNTGGTGYTTYATGACNTGGAARTGGGGN TTYYTNYTNYTNATHTAYTCNMGNTCNTAYTAYMGNACNTAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNGAYAAYCCNGCNGGNGTNGARTAYGGNTCN MGNYTNACNGTNAAYYTNCCNGCNYTNAARGGNGARAGYTTYACNGTNGAYATHCAYTAY AGYACNTCNCCNAAYTCNTCNGCNYTNCARTGGATGACNYTNGARCARACNGCNGGNAAR MGNCARCCNTAYYTNTAYAGYCARTGYCARGCNATHCAYGCNMGNAGYYTNTAYCCNTGY CARGAYACNCCNGCNGTNMGNTTYACNTAYAAYGCNCARGTNGARGCNCCNAARGARATG ACNGTNYTNATGAGYGCNAAYCAY------MGNGARGTNACNGARGGNTCNGGNGGNGAR AGYGTNACNAARTTYGTNATGGAYATHCCNATHCCNAGYTAYYTNYTNGCNATHGTNGCN GGNGAYYTNGARTCNMGNGARATHGGNCCNMGNACNMGNGTNTGGTCNGARAARGARATG GTNGAYAARGCNGCNTAYGARTTYGCNCARACNGARTCNATGYTNGTNGTNGCNGARGAY YTNATGGGNCCNTAYGTNTGGGGNCARTAYGAYYTNYTNGTNYTNCCNCCNTCNTTYCCN TAYGGNGGNATGGARAAYCCNTGYYTNACNTTYGTNACNCCNACNYTNYTNGCNGGNGAY MGNTCNYTNGTNAAYGTNGTNGCNCAYGARATHTCNCAYAGYTGGACNGGNAAYYTNGTN ACNAAYGCNAAYTTYGARCAYTTYTGGYTNAAYGARGGNCAYACNGTNTTYYTNGARMGN AARATHCAYAGYMGNYTNTAYGGNGARGCNAAR---MGNGARYTNCAYGCNCAYMGNGGN TGGAGYAAYYTNATHAARACNGTNAAYACNYTNACNGARGAYAARCAYAGYGAYTAYACN MGNYTNGTNCCNGAYYTNTGYGGNATHGAYCCNGAYGARGCNTTYTCNTCNGTNCCNTAY GARAARGGNTTYGCNYTNYTNCARCAYYTNGARACNYTNYTNGGNGGNCCNGAYGTNTTY AAYGTNTTYYTNAARGCNTAYATHGARCAYTTYAARTTYMGNTCNATHYTNACNCARGAY TGGAARGAYTTYYTNTTYGGNTTYTTYAARTCNGAYGARGAYAARMGNMGNYTNGCNACN GTNGAYTGGGAYCARTGGYTNCAYGGNGARGGNATHCCNCCNTTYACNCCNGAYTAYGAY YTNAGYYTNACNGARATHAGYMGNGARYTNAGYCARMGNTGGATHGAYMGN------GGN AGYGARGAYGTNTTYTCNTGYGAYGAYATHAARGAYATGAGYTGYGAYGTNGTNGARGAY TTYYTNTCNMGNYTNATHCARGCNAARCCNCCNATGTCNYTNCCNAARATHCARGARATG GARAGYGTNTAYMGNYTNAAYGAYGTNAARAAYGCNGARATHMGNTTYAARTGGYTNGAR YTNTGYATHCARGCNMGNTGGGCNGAYGCNATHCARCAYGTNYTNAAYTTYYTNAAYGAR CARGGNMGNATGAARTTYGTNATHCCNYTNTAYMGNGCNATGAGYAARTGGGARGARGGN MGNAARGCNGCNTTYGARAAYTTYACNAGYCAYMGNTTYGARATGCAYAGYACNACNGTN AARAARGTNGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ACNCCNCCNCCNTCN AARMGNAARAARMGNGAYACNGARTCNTCNGAYGARGGNGTNGGNTGYYTNTCNGAYGCN TCNGAYGAYTGYGGNACNGAYYTNMGNCARAARAAYGARGCNYTNAARCAYCARATGGAY MGNGARMGNCARMGNGGNGAYTCNYTNGARGARGARAAYMGNAGYYTNMGNAAY---YTN ATHYTNATHCARAARCARAGYGCNMGNGAYCARCARCCNATHACNYTN------------ GCNGCNGCNCCNCARGAYATGMGNGARATHGTNGARGTNATGTCNCCNMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNATGGAYAAYCAYGAR GARATHYTNGAYGCNYTNACNGCNTTYGGNAARAGYCCNAAYCCNCARGARATHCCNTCN GTNYTNGARCARTAYYTNAAYTTYGTNGCNAARAAYGGNGARACNYTNTTYCCNTGGTCN CARYTNAARCCNYTNATHYTNAARAARATGGARYTNGTNTTYACNGAYYTNMGNCARAGY YTNGGNTCNGARAAYATHCCNAAYMGNCCNAAYGTNGARAAYGTNMGNTTYGAYGTNATH CAYGCNMGNATHATHGAYTCNYTNCAYAARTTYAAYGGNGCNCCNTTYACNATHCARMGN YTNTGYGARYTNYTNYTNAAYCCNAARAARCAYTAYAARMGNAGYGAYAARTTYATGMGN GGNYTNGARAARAAYGTNYTNGTNGTNAGYACNGTNGAYCCNTTYGGNMGNAARGTNGTN TGYGARTCNGGNAAYAARCCNATGYTNAAYGGNATHYTN---GAYATHAAYGGNTCNTCN CAYCCNYTNMGNGAYACNGGNYTNAGYATHCCNYTNCCNCCNGTNCCNGGNTGGGTNACN AGYGCNACNTCNATHACNCCNCCNGTNMGNTCNGGNGGNACNATGCCNTCNYTNGAYTCN AARGCNGGNACNAAYATGGARAGYYTNGGNGAYGCNGGNGTNGTNTCNAAYAGYATGTCN GGNGGNATGGCNGTNTCNGGNTCNGTNTTYTCNGAYCARGGNGAY---CCNYTNGCNGTN CAYTCNGARGARGTNGTNGARGARACNGTNGTNACNATGGAYACNGGNGARGTNACNTCN GTNGTNACNGAYGGNGGNGARGGNATGGCNGARMGNGARGCNATGGARGGNGAYATG--- GCNGAYGAYMGNGARGCNTCNTCNTTYTCNTCNTCNTCNTCNTCNTCNTCNGARGARYTN TCNTCNTCNGARTCNGTNGARAAYGGNCARMGNGTNTCNCCNTTYGGNGTNGCNGGNAAY AGYGCNTCNYTNGAYGARAAYMGNCCNTGGGCNGCNTTYGCNCARGAYGTNAARCARGAY GARAAYCARTCNGCNGARAAYYTNTCNGAYGARAAYCARACNTCNGGNGTNTCNTCNTCN TCNCCNCAYCAYACNTCNCCNGARGCNYTNTCNTCNTCNTCNCCNGCNGCNCCNCCNTCN TCNGAYACNCCNCARTCNTCNTCNTCNTCNGCNACNACNTCNTCNAARGTNGARGAYGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GTNACNGCNYTNCCNGCNTCNTCNACNAAYACNACNACNACNACNACNATG ACNGGNTCNTCNCARGTNGCNGTNTCNACNGGNTCNAAYATGYTNTCNTTYCCNGTN--- ------GGNYTNACNCARYTNATGCCNGTNACNTCNAARGGNCARGCNGGNCARACNATH MGNCCNACNGCNATGCCNYTNYTNCARYTNCARGGNCARCARGGNATHCARYTNYTNAGY YTNCARCARMGNGGNCARGTNAARCARGGNACNAGYAAYTCNAAYGCNGCNCARGGNATH ACNMGNYTNGCNCARGCNGGNACNACNACNGTNCCNYTNTCNACNGTNYTNGCNGGNCAR CARATGACNGCNYTNGGNATGGGNAGYAARCCNGGNCARGGNGGNAGYACNGCNATHACN GCNCARCARYTNATHCARYTNACNGGNGGNCARGGNACNTCNYTNGGNCARGGNACNGCN CARMGNGCNGCNCAYATHACNTTYGGNAARGGNCARCARGGNYTNCARTTYCAYTCNYTN CARYTNAARCARGGNGGNGCNACNYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AGYCCNAAYTCNTCNTTYGGNAARAGYAGYGGNCARAARGARGGN--------- ---GGNGGNCCNTCNGAYAARCARGCNACNAGYCCNAARTCNAGYMGNGARAAYACNCCN GARAARMGNTCNTCNGARMGNGARAARTCNTCNGARMGNGARAARACNCCNGARGGNAAR GGNAARGGNAARCARATHTCNACNTCNCCNTCNGARTCNACNCCNTCNACNTCNCARTCN GCNCCN------------TCNACNTCNTCNGGNTCNCCNGCNGARAARAARMGNAAR--- GGNATGGGNGARGARGARYTNAARCARGCNATHAARMGNTTYAARAARCARGAYGARGAR MGNATGAARATGCARGTNYTNGTNTCNAAYTTYTCNGARGARCARYTNAAYMGNTAYGAR ATGTAYMGNMGNGCNACNTTYCCNMGNGCNGCNATHAARMGNYTNATGCARAAYATHACN GGNACNTCNGTNTCNCARAAYGTNGTNATHGCNATGTCNGGNATHGCNAARGTNTTYGTN GGNGARGTNYTNGARACNGCNYTNGAYGCNAGYGARAARTGGGGNGAYTCNGGNCCNYTN CAYCCNAARCAYYTNMGNGARGCNGTNMGNATHYTNAAYTCNAARGGNACNATGCCNTCN ACNAARAGYAARAARACNYTNTTYTCNATHATGTCNGCNAAYAARACNGTNCARGTNCCN AGYCARAAYAGYYTNGGNCCNYTNCCNGCNTGYATHAGYGGNGAYCCNACNAARTGYACN AARGGNYTNATHGTNYTNCARGARTGGTGGGGNATGAAYGAYCARATHCARGCNTGYGGN CARGAYYTNAGYAAYCARGGNAAR---ATGGTNACNYTNGTNCCNGAYYTNTAYMGNGGN AARGTNACNACNGAYAAYGARGARGCNGGNCAYTAYATGAGYAAYYTNGAYTGGCARGGN GCNGTNYTNGAYATHCARGCNGCNGCNMGNTAYYTNATHGGNCARGGNGTNAARAARGTN GCNGTNACNGGNTTYTGYATGGGNGGNGCNYTNTCNATHGCNGCNGCNGCNAARGTNCCN GARGTNTCNGCNGCNATHCCNTTYTAYGGNATHCCNTCNTCNGAYYTNTGYGAYGTNACN ACNATHAARGTNCCNATGCARTGYCAYTTYGCNGARAARGAYGCNACNGCNGGNTTYGCN TCNCCNGCNGARTGGAARCCNYTNAARCARAARATHGARGGNAARYTNAARGAYYTNGAR TTYTAYGARTAYGAYGCNGGNCAYGCNTTYACNAAYAARACNGGNGAYAAYTAYAAYAAR ACNYTNGCNGAYYTNGCNTTYTCNMGNATGTTYACNTTYYTNGARAARCAYYTN------ ------------------------------------------------------------ ------------------------------------------TGGGGNCAYYTNAARGAY GTNAAYTCNTGYCAYGCNYTNGAYTAYGGNTGGAAYACNTCNCAYTGYTGYCARGARGTN TTYAGYACNYTNCAYATHGAYACNAARAAYGTNYTNTTYAGYCARAARAARCARCCNGTN CCNTTYTAYACNTCNGGNYTNGGNATHYTNGARCCNATHMGNGGNGGNCCN---AAYCCN GCNGARAARAGYCARCCNCCNGTNCARCCNACNYTNYTNGAYACNGGNAARCCNGARGAY ------CCNAARAARGTNYTNGAYATHCCNCCNGTNGAYTTYGAYTGGGGNTCNAGYGGN YTNACNAAYCCNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGGCNGAYTGGAAYTCNGTNGGNGTNYTNYTNAGYAARYTNTCNACN AGYGAYATHAGYAAYGTNTGYCAYYTNATHGCNGARAGYTTYTGYCARGAYMGNGCNATH AARTCNGAYCARYTNAAYTCNACNTGGTCNYTNGARGARTGGTGGGARGTNMGNGGNGCN YTNYTNGCNYTNATGMGNAARGCNGTNCARCARCAYTGGAGYMGNGAYCARATHTAYGGN GARYTNGGNCARGTNGAYGAYGCNTAYAARAGYGTNATHACNGARGCNATHAAYGTNCAY MGNCCNGCNYTNAARCARAARYTNYTNCARAAYACNAGYGCNATHTCNCAYGCNGTNYTN TCNGAYTTYGAYTGGAARYTNCARYTNGCNYTNTCNAGYGAYAARATGTCNAGYYTNCAY CARCCNTTYYTNYTNYTNGAYYTNGAYGTNMGNCARGCNGAYGGNGARMGNAARCARGTN GCNYTNGARATGGAYAARGARGARYTNGCNAARYTNATHACNTCNYTNGARAGYTGYAGY AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AAYTTYTCNGARGTNYTNGGNGARYTNGGNCARGAR TCNAARATGGTNATGYTNCARTAYTCNCARACNTTYTGYGAYAGYGARYTNTAYGARCAR CARGGNYTNCARGCNGTNACNGAYYTNGCNGCNCAYGCNAARATGYTNGARCARAGYYTN AARTAYCARAARGARYTNYTNTGYAAYMGNYTNAARATGATHACNCARAAYYTNAARAGY GAR---------GGNCAYGGNCAYGGNGGNAGYGGNAARCCNYTNGARTTYGCNTCNGAR ATHCAYAAYAARGAYCAYATHYTNGAYCAYYTNCARCAYGTNATHTCNACNAARCCNAAR GARCARYTNACNGAYGARGARYTNGARTTYCAYTAYTTYAARYTNCAYGAYTAYGAYAAY AAYAAYAARYTNGAYGGNGTNGARATHGGNAARGCNYTNACNCAYTTYCAYGAYGAYCCN GCNTCNGARGCNAAY------------AARGARAAYAARGARCCNCCNAARGTNTTYTCN GAYGAYGARATHTCNAAYATHGTNGAYTCNGTNATHGAYGARAAYGAYGGNAAYAARGAY GGNTAYATHGARTAYTTYGARTTYAARTCNAARCARGCNGARATGAARCARACNAGYGGN ACNAAYCARCARCARCARGGNCARCARCCNATGGGNMGNGGNMGNTCNAGYGAYTCNGAY AGYGAYTAYTCNMGNTCNAARMGNAARAARAARMGNMGNGCNMGNTCNMGNACNMGNTCN AAYAGYTCNAGYGGNTCNAGYMGNYTNTCNAGYCAYAARAGYAARAARTCN---AARAAR AGYAARMGNTCNAGYMGNAARTCNTCNGTNAGYCCNGAYMGNCAYAARAGYGARMGNGAR MGNTCNMGNMGNTCNMGNTCNMGNTCNACNGAYMGNMGNACNTCNMGNMGNTCNMGN--- ---TCNMGNTCNCCNGARGTNTCNTCNMGNTAYMGNTCNMGNACN------------MGN TCNAARTCNCCNTCNTAYTCNMGNGAYMGNMGNTCNMGNTCNGGNTCNMGNGGNCAYMGN YTNAARGGNMGNCAYMGNMGNTCNMGNTCNCAYTCNAGYTCNAARGGNTAYGARMGNTCN MGNTCNACNTCNMGNCAYMGNGARMGNTCNTCNMGNCAYGAYAGYCCN------------ ---------------------GAYMGNCAYAARACNGAYCARGGNAAYGGNATGACNTCN TCNGARYTNGCNGARYTNMGNATGMGNAARGCNYTNCARGCNGCNGCNGCNGCNGAYGAR AARYTNAARAGYYTNAGYGGNTCNTCNGTNAAYGGNTCNTCNGARCARYTNTCNGCNYTN ACNYTNACNGCNACNTCNCAYGCNCCNACNTCNTCNAARAAYTTYGCNAAYAARGTNGCN GCNATHGARTCNGAYAGYTTYGCNCCNGCNTCNTTYMGNTCNTCNGGNATHGTNGTNATG GARGAR---CARATHGAYCCNYTNATGTCNAGYCAYGAYGAYGCNATHTTYGGNTCNYTN TCNTCNGTNGGNTTYACNATHAARCCNGAYCCNGAYACNAARCCNGTNTCNYTNGAYCCN GARTCNATHATGCAYCCNMGNYTNTTYTGYAAYGTNGARGARAARATGGAYMGNTGGATH GARMGNYTNTCNCARYTNMGNMGNMGNAARYTNGARGGNGARGTNATG------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GAYGCNAARGAR GCNTGYAARATHYTNCARGAYACNAARGGNTGYAARTCNGTNATHATHACNYTNGGNGAY AARGGNGCNGTNYTNAARGAY---GCNTCNAARGARGCNGTNCAYGTNGCNACNTCNCCN GTNAARGCNGTNGAYACNACNATGTCNTTYCCNGGNMGNGCNCCNATGGCNATGCCNGGN GGNATGCCNGGNATGGCNCCNMGNATGATG---ACNCCNGGNTAYGCNTTYACNTCNATG GGNATGACNMGNATGAAYCCNATGATGCCNATGCARATGGGNATGATGACNCCNATGATG CARCCNATGATG---CARCCNCARATGCARATGCARCAR---CARCARCARATGAARCAR AAY---AARTTYATHCCNCARGARATHCCNMGNACNGAYTCNAARGGNGARAARCCNCCN GTNACNACNGTNTTYGTNGGNAAYATHAGYGAYMGNGCNCCNGAYATGATGATHAARCAR ATGYTNCARMGNTGYGGNAAYGTNYTNAGYTGGAARMGNGTNCARGGNGCNTCNGGNAAR YTNCARGCNTTYGGNTTYTGYGARTAYGARGAYCCNGARGCNACNYTNMGNTGYATHMGN YTNYTNAAYGAYTGGCCNATHGCNAGYAARMGNYTNGTNGTNAARGTNGAYGCNAARACN AARACNYTNYTNGAYGARTAYMGNAARAARAARCARGCNAGYGARGCNGCNGCNGTNAAR AARGAR---------------CCNGAYGCNAAYGARAARAARGARAAYGGNGARGARGAR AARGARAARAARGAYGAYGTNAARGARGARGARAARGARAAY---GAYYTNGAYGARAAY ACNAARMGNGARGAYMGNGTNGCNCAYGCNGGNYTNGARGCNATHATGMGNGARTAYGCN TTYGARYTNGCNAARGARCCNGCNAARTCNGCNGAY---GCNGTNCARGAYAARGARAAR CARYTNCCNAARAARGAYAARGARATGTTYATGCAYGCNAARGAYACNGGNTTYGAYGAY ATGGARATGGARGAYGARAARMGNGARATHATHAAYMGNGARATHAAYAARTTYMGNGAY MGNCAYAARGAYGAYGAYGARGARAARGARAARGAYAAYMGNGARAARGARMGNAGYYTN GGNMGNGARMGNGARMGNMGNCARGARGARAARMGNCARMGNGARMGNYTNGARAARYTN MGNGARCAR------------------------MGNGAYMGNGARMGNGARMGNTCNAGY ACNMGNGTNTCNMGNTCNAARTCNMGNTCNGCNTCNCCNGTNATHTCNMGNTCNMGNMGN MGNTCNMGNTCNMGNGARMGNGARMGNGARMGNAGYAGYMGNGAYMGNTCNMGNGARMGN MGNAARGARMGNGARATHGARGARGARGARGARYTNTAYGARMGNMGNAARYTNGARAAR AARYTNMGNGARAARGARGCNGCNTAYCARGARMGNYTNAARAAYTGGGARGGNMGNGAR MGNAARAARACNMGNGARTAYGARAARGARAAYGARMGNGARGARGARMGNAARATHGAR GARGGNMGNGARGCNMGNMGNYTNAARGARTTYYTNGARGAYTAYGAYGAYYTNMGNGAY GAYCCNAARTTYTAYAARGGNAGYGCNYTNCARMGNMGNCARAARGARMGNGARAARGAR AARGARYTNGAYAAYMGNGAYMGNCARMGNGARAARGARGARTTYGARGARATHAARMGN AARYTNTTYGAYGARGGNCAYCCNGAYGCNGARACNGARGTNGCNMGNATGGARMGNGAR MGNGARGARCAYYTNCARCCNMGNYTNCAYYTNCARGARYTNAARCARCCNCCNCCNCCN CCNGCNGARCCNGCNCCNGCNATGGARGARTCNGARTCNGAYGARGARGCNTCNGGNGGN GCNGARGTNMGNCARGCNTCNCCNAARCARCCNGARCAYCCNCARTCNMGNAAYYTNTCN AGY------------------TCNCAYCAYCARCAYCAYYTNGCNGTNCCNGARCARMGN CCNTCNCCNTCNYTNTCNACNTCNCCNATHTCNACNGAYTCNMGNGTN---AGYGCNCCN NNNYTNTGYATGGAYGARTCNTCNCARTCNTCNYTNCCNACNGTN------CCNCCNYTN TCN---GCNTAY---GARGARACNMGNYTNGGNACNMGN--------------------- ACNACNTCNYTNGCNCCNAGYGTNAGYCCNGAYTCNTCNAGYYTNCCNGGNGTNCCNAGY GTNTCNGAYGGNAARMGNAARAARYTNACNGTNGGNGAYGTNTTYAAYCARGAYGAYGAY GAYAGYAAYGARCCNAARAARMGNAARYTNATHCCNYTNGAYTAYGAYGAYGARAARTCN ACNCCNACNGARAARAARGGNGCNACNGCNGARGARAARMGNCARAARATHAARCARYTN ATHGARAAYATHCCNACNGCNAARGAYGARYTNTAYGCNTAYACNGTNGAYTGGGAYATH GTNGAYCARGGNYTNATGGAYAARMGNATHAARCCNTGGGTNACNAARAARATHGTNGAR TAYATHGGNGARGARGARCCNACNYTNACNGARTTYATHTGYCARAARGTNATHGCNMGN AGYACNCCNCARAGYATHCARAAYGAYGTNGCNATGATHYTNGAYGARGARGCNGARGTN TTYGTNGTNAARATGTGGMGNYTNYTNGTNTAYGARACNGARGCNAARAARATGGGNYTN GTNAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AARACNCCNAGY GTNCARMGNATGTGGYTNGGNCARCARGAYGGNGAYAARGAYMGNMGNYTNMGNGCNTTY YTNACNATHATGATGAGYGAYACNAGYYTNATGYTNAAYACNAAYTAYATHCCNCARCAY YTNYTNGTNATGTGYTGYGTNYTNMGNTAYATGYTNCARTGYGGNMGNATHYTNCARMGN CCNGARYTNGAYGCNTTYYTNGCNATGTCNGTNTCNCCNYTNYTNMGNGAYATHCARACN ATGCARGAYYTNAARYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATGGCNGAYGAYTCNGAYATHCCNCCNYTNGARGAYATGACNGARATHGTNAAR AARGCNGARYTNATHMGNGARCARMGNTTYGGNTCNGGNAGYCARGCNAARGAYACNAAR CARAAYGTNGAYGCNAARAARMGNGCNAARGTNACNAARAARAAYGTNCARAGYGGNGTN TCNTCN---------------GTNACNGARGARGTNTCNAAYACNCARAGYAARYTNCAR GARGTNTCNATHACNCARAAYAARYTNGGNGAYGGNGAYGGNGARGGNGARAARAARGCN AGYAGYTCNACNAARACNAARCCNCCNAGYCARGGNYTNTTYGGNGGNATGAARAARGGN TTYYTNTTY---GGNGCNCCNAGYAAR------------CARACNACNAARTCNTCNTCN AAYAARGCNYTNAGYGGNAGYCARGGNGAYGGNCAYACNGAYCARGTNGARAARAARAAR AGYACNACNACNGAYAARGARGAY---YTNCCNTAYATHACNCCNTCNGGNAARACNGAR TCNGGNYTNACNYTNGAYGARGTNCARCARGCNATGTCNGARACNAARGGNYTNATGGAY AAYCARGAYTGGATHACNGAYGAYYTNYTNACNAARATHGARAARAAYGAYACNYTNYTN AARMGNTTYAGYGAYCCNAARTTYATGTCNGCNYTNCARGARTTYCARACNAAYCCNGAR TCNGCNATGGCNAARTAYAARGGNAAYACNGARGTNGARAARTTYYTNATGGARTTYTGY GGNYTNYTNGGNGAYCAYYTNACNAAYTTYGGNAAYAARACNGARACNCCNCARCCNGGN CAR------AARCARCCNCCNAARAARCCNCCNCCNTCNACNATGACNGARTCNAARCAR TCNAAR------GTNACNCCNTCNACNACN---------------------------CCN AARATHGTNGARATHGGNGGNGAYTGY--------------------------------- ---------------------------GAYGAYACNGCNAARGCNGARCCNAARATHACN AARTCNACNAARYTNAGYACNGTNCCNAARACNAAYGCNAAYTCNGGNTCNCAYATHMGN ATHCAYGAYACNCARAGYGGNGCNGAYATGCARGARGTNCCN---------------CAR ACNGAYGAYGARGCNGTNAARGARGTNYTNAAYGAYCCNMGNGTNATGGARCAYYTNATG GAYCCNMGNGTNATGAGYYTNATHAARTGYYTNMGNGARAAYCCNGCNGARGGNCARMGN ATHGTNGAYAAYGCNGAYTCNGARYTNAARGGNAARATHMGNTTYYTNGTNTCNAARGGN YTNYTNCARTTYCAR---------AAYAARTCNMGNCCNGCNAAYGTNAARTCNYTNYTN YTNCARGAYTAYGARAAYGARATGYTNTTYCARACNYTNGGNMGNYTNTGYGTNACNYTN GCNACNGGNGTNGTNCARYTNTAYTTYGCNGAYCARGCNGAYMGNACNMGNTGGAAYAAR MGNTGYTGYGGNGTNGCNTGYTTYGTNAARGAYAGYTCNAARMGNTCNTTYTTYATHAAR GTNTTYGAYATHAARAARCARCARATHYTNTGGGARCARGARYTNTAYAAYCARTTYGTN TAYAARACNCCNMGNGARTAYTTYCAYACNTTYGARGCNCARAAYTTYCARGTNGGNYTN AAYTTYGCNGAYGARGAYGARGCNATHAARTTYAARAARGCNGTNGAYGGNAARYTNAAY GARMGNATHAARAARAARAAYGARMGNMGNCARAARTCNGTNTCNCARMGNAARACN--- ------TCNGARGGN---------GGNAGYATHGTNCCNCARMGNACN---ACNCARAAY GCNGCNGCNCCNACNCCNGCNGTNACNACNAAYGTNAGYMGNCCNAGYAAY------AAY ACNCARAARAARGARAARGARAAR---AARAARGAYGGNGGNAARAARAARYTNACNAAR GCNGAYATHGGNACNCCNTCNAAYTTYATHCAYGTNAGYCAYGTNGGNTGGGAYCCNGAY AARGGNTTYGAYATGAAYAAYYTNGARGCNGAYATGCARATGYTNTTYCARTCNGTNGGN ATHAARCCNGARGAYMGNGTNGAYAARGARACNGTNGAYTTYATHTAYGAYTTYGTNGAR AARCARGGNGGNATGGARGCNTTYAGYAARGARYTNYTNAAYAAR------------GCN CCNCCNCCNCCNCCNAGYCARGGNMGNACNATH------CARCCNCCNCCNCCNCCNTCN MGNGCNCCNGCNGCNYTNCCNCCNMGNGGN---GGNGCNCCNCCNCCNCCNCCNCCNCCN TCNMGNGGNGCNCCNCCNCCNTCNATGMGNGGNACNCCNCCNCCNCCNCCNCCNTCNMGN GCNATGCCNGCNCCNCCNMGNGCNCCNGCNGCNGCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGGCNGCNYTNTTYGGNGARAGYMGNYTNYTNACNAARAARGTN TTYGAYGARATHTAYGTNTCNGARAARGAYMGNGAYAAYTAYAAYACNGTNCARGCNAAY GARGTNYTNGARGGNAARGTNGTNTGYYTNTTYTTYTCNGCNTCNTGGTGYACNCCNTGY CARCAYTTYGTNCCNTAYYTNAARGARGTNTAYTCNGARYTNYTNCARMGNAARAGYCCN YTNGARATHATHTTYYTNAGYTTYGAYAARACNGARGARGARATGATGGAYTAYTAYCAR AGYAARCAYGGNGAYTGGYTNGCNGTNAARYTNGGNGAYCCNYTNAARCARGAYYTNGCN GARMGNTAYTCNATHAGYGTNATHCCNAARYTNATHGTNATHCARCCNGAYGGNGARGTN ATHAGYAGYAARGGNMGNAARGAYGTNCARGAYMGNGGNGTNGTNTGYATGMGNGCNTGG CARGCNGGNTTYGAYAARTAYGTNCAYCAYGAYAARGARYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYATHTCNGCNATGMGNAARACNTAYMGNGGNAAR CARGAYGTNTTYGAYYTNAARGAYYTNGTNTCNAARGARCCNTTYGAYCARTTYTCNAAY TGGTTYGARGARGCNMGNACNTCNCCNGAYATHYTNGARGCNAAYGCNATGGCNYTNGCN ACNGCNACNMGNGAYGGNCARCCNTCNGTNMGNATGGTNYTNATGAARGGNATHAGYAAR AARGGNGTNGARTTYTAYACNAAYTAYYTNAGYMGNAARTCNCARGARYTNATGGARAAY CCNCARTGYAGYGTNGCNTTYTAYTGGGCNCCNYTNAAYAARTCNGTNMGNATHGARGGN MGNATGGARAARYTNAGYCARGARCARTCNGARAARTAYTTYCAYTCNMGNCCNMGNTCN AGYCARATHGCNGCNTGYGTNAGY---CARAARCARAGYGGNACNGTNTCNTCNMGNGAY GTNYTNGAYAARMGNAAYGARGARYTNCAYGCNCARCAYAGYGAYGARACNGTNCCNGTN CCNAARCCNGARTAYTGGGGNGGNTTYMGNATHGTNCCNCAYMGNTTYGARTTYTGGCAR GGNCARACNAAYMGNATHCAYGAYMGNATHGTNTTYMGNAARYTNGAYGARGGNGARACN ATHGAYCCNACNGTNACNTTYCAYGGNAGYGAYGGNTGGYTNTAYGARMGNYTNGARCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GCNGARGTNTAYATHGTNGARATHGAYCCNATHATGGAYTAYCCNMGNCCN ATGYTNCCNAAYACNAARYTNGTNGGNGGNACNGCNGTNMGNAARGCNAARTAYYTNAAY GARCCNTTYAARAGYTTYGTNGAYAAYTCNAARACNGGNGTNATHGTNATHTCNTTYGGN ACNMGNGTNYTNGAYGTNCCNGARTAYATHTTYAAYAARATHCAYACNGCNTGYAARMGN TCNGGNYTNAAYATHGTNTGGMGNTCNGAYCARCCNTCNCCNGAYACNGAYAARATHYTN ACNAAYGARTGGATHCCNCARAAYGAYATHYTNGGNCAYAAYAAYACNAARYTNTTYATH TCNCAYTGYGGNAARAAYGGNCARTAYGARGCNYTNTAYCAYGGNGTNCCNATHYTNTGY YTNCCNTTYTAYGCNGAYCARCCNTAYAAYGCNGARMGNGTNMGNGCNAARGGNTAYGGN YTNAARGCNGAYATGMGNTCNATHTCNACNGAYGAYYTNTCNGAYATGATHAARGARATH ATHACNAAYACNACNTAYAARACNAAYATHGCNAARGCNTCNAARYTNTTYMGNYTNYTN TAYAARTCNCCNATGAARGARGCNGCNTTYTGGYTNGAYCAYGTNATGGARTTYGGNGGN GAYTAYATGMGNGCNGCNAGYCARAARATGCCNTAYTAYCARTTYYTNATGYTNGAYGTN NNNGCNGTNNNNYTNTTY---------------------------------------MGN AGYTTYCARCCNYTNCARTTYGCNAARMGNAGYTTYMGNAGYCARAARACNACNGTNCAR ACNAAYCCNGTNCCNAARACNGARCCNCARGGNGAYTCNTTYTCNTTYATHAARTCNGCN GCNTTYGTNACNGGNGTNTGYAGYTGYAGYTTYGTNGGNGCNATGATHTGGAAYTAYGAR AAYGTNMGNAARGTNTAY------------AARGAYATGGCNYTNGARGAYAARCCNGCN MGNCCNMGNCAYGARAARGTNYTNGGNTTYMGNCARCAYYTNAAYGCNATHTGGACNGGN YTNGAYTCNTCNACNAARYTNACNTTYGGNATHATHGCNGCNAAYGTNATHGTNTGGGGN ATGTGGAARGTNCCNMGNTGGCARTCNGGNATGGTNMGNTAYTTYTCNTCNGCNGCNGCN CAYCCNMGNTCNTCNATGGTNYTNAGYAGYTTYAGYCAYATHAGYATHTTYCAYYTNTTY GTNAAYATGTAYGTNYTNYTNTCNTTYGCNCCNGTNGCNACNMGNGTNTTYGGNCAYGAR CARTTYTCNGCNTTYTAYATHAGYGCNGGNACNATHTCNGCNTTYACNAGYATHYTNTGY CARMGNYTNYTNMGNMGNCCNYTNTCNATHTCNGTNGGNGCNTCNGGNGCNATHATGGGN YTNYTNGGNGTNACNGGNATHGTNTAYCCNAAYGCNCARYTNCARGTNGCNTTYATHTCN GARATHATHCCNCAYTCNTTYTCNGCNGARACNGGNATHAARGCNATHGTNYTNTTYGAY YTNATHGGNYTNTTYATGGGNTGGMGNGTNYTNGAYCAYGCNGGNCAYYTNGGNGGNATG YTNTTYGGNATHYTNTAYGCNAARTAYGGNAAYAARATGATHTGGGGNMGNMGNGAYACN GTNGTNAARGTNTGGCAYGAYATHMGNGGNAARCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GTNCCNCAYATGGGNGTNCCNTTY MGNCCNCARYTNGARCAYAARCAYACNATHACNAARCCNTTYGCNGTNGARCARCAYAGY AARGARATGYTNAARAARMGNGARCARAARAARCARCARGTNTTYGARGARGARAARAAR GCNMGNGARTTYYTNGCNACNYTNYTNCCNAGYGAYAGYCCNGAYCARYTNCCNCCNAAR AARACNMGNCCNGTNACNGCNCCNGARCCNTTYAAYTTYACNGTNGAYGARMGNGGNAAY AARTAYAARGARGARTGGAARTCNAAR---ATHGARGARGARAARGARCARGCNMGNACN MGNTCNCARTTYCAYGCNACNTCNAAYAARGTNGTNTTYAARCCNCCNTTYGTNCCNGAR AARTCNAAYMGNCARYTNACNGARATGAGYAGYTTYACNYTNAAYACNGAYYTNMGNTCN GGNAARMGNGARGGNTTYAAYCARAARATHAARGCNCAYGARGCNAGYGCNGCNGCNGTN AARMGNCARCAYGARGARATGGARAARMGNGARGAYAAYAARGCNGTNGCNCARYTNMGN CARGAYATHGTNCAYAARGCNACNGGNATHAARAARTAYAARCCNGTNAARYTNCARCCN AGYGAYAARCCNYTNACNGTNGCNCAYTCNCCNTGYYTNACNCAYAARYTNMGNACNAAR ---------------CAYCAYGGNGAYAARGAYGAYCCNCAYGGNGGNGTNCCNATGGGN ATHTCNAAYTCNTTYTGYGAYGAYGGNCARAAYTTYACNCARACNGAYTGGGAYTCNGAY TCNACNGARGARTAYACNTGYYTNGARGARACN------------GAYGAYYTNGAYATH YTNMGNGAYAGYCAYGARGARTGYGARAARGTNGCNAARMGNCCNATHCAYGTNTGYTTY CCNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CCNTTYGAYTCNAGYAAR AARAGYCAYATHGAYAGYGTNYTNATHCCNGAYATGGAYGAYGCNGTNGTNMGNATHGGN MGNATGMGNAARAAYCARCCNTCNAARTGYAARMGNGARGCNYTNAARATHGCNGCNAAY TCNGTNAARTAYTAYAGYCAYGTNACNGTNGARTGYGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNGAYATHATGAARGGNAARACNYTNGCN CARAARGTNTTYTCNGARTCNCCNATGYTNTCNTCN------GCNAAYATGTCNTCNGAY GGNYTNGAYGGNGAYMGNTCNTGGGARAARCAYACNAAYACNTTYAARCCNCCNGTNCCN GTNGGNAAYTGYGAYAAYTAYGGNAARGTNAAYGGNTGYGGNGAYAAYATGCARAARAAY YTNTCNGCNAGYYTNTCNGGNGGNAAYCARCCNGGNAGYATGGARACNYTNAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNTCNGAYGARTCNAAYACNAAYAGYAGY TTYACNGTNACNGTNAARAARYTNGAYGAYGARTCNGCNTTYCCNTAYTCNGGNMGNGAR GGNCARGTNGCNAGYAGYGTNTCNAAYAARGTNTAYGTNTTYGGNGGNGTNGARCARGGN CARGGNGAYGARCCNAARGARACNAAYGARYTNATHATHTTYGAYATGGCNTCNCARAAR TGGTCNAARCCNTCNGTNYTNGGNTCNCCNCCNGCNGCNMGNTCNGCNTCNTCNYTNGTN GCNGTNGGNACNAARYTNTAYYTNTTYGGNGGNYTNAGYCAYATHTGYGGNTGGTTYGAY GAYGTNCAYGTNTTYGAYACNGTNACNAGYACNTGGTCNATHGTNGAYACNGARGGNACN AARCCNMGNGCNMGNGAYAARYTNCARGCNGTNGCNATHGAYACNAAYATHTAYTAYTTY GGNGGNTTYGGNCCNAARTCNGAYGARGCNGARATHGAYGAYYTNGCNGGNGAYGAYGAY GAYGARTAYGARGAYGARGARGAYATHCCNGARAGYCAYGARCARGAYGGNGCNGARTTY GGNTGGTTYAAYGAYYTNTGGGTNYTNGAYACNYTNACNYTNAARTGGTTYCARCCNATG CARATGAAYYTNGGNGTNCCNACNCARMGNGCNGCNCAYGGNATGTGYGCNGTNGGNMGN AAYYTNGTNATHTTYGGNGGNMGNGAYGTNGARGAYMGNCARAAYGAYGTNCAYATHTTY AAYATHGAYACNAARAARTGGATGACNGARYTNCARATHAGYGGNCARCCNCCNGCNCCN MGNTCNTTYCAYACNYTNACNGCNGTNGGNGAYAARGTNGTNGTNTTYGGNGGNMGNGGN MGNGAYAAYAARCAYTTYGAYGAYTTYGAYGTNYTNGAYGTNGARAARAARGARTGGACN MGNGCNTCNATHGAYGGNTAYAARCCNCCNGCNMGNGGNCARCARAGYGCNYTNACNGTN GGNGAYACNTTYYTNGTNTTYGGNGGNTCNGGNGARTTYAGYCCNGARATHATGCARTGY CARACNTTYYTNMGNGAYACNTTYTTYATHAARACNGAYTCNTTY---TCNACNGGNAGY AARTCNAAYGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GGNAARGTNTGG CCNGGNACNACNGTNTGGCCNGAYTTYYTNTCNCCNAARTCNCARGARTAYTGGACNCAR GTNGTNAGYGCNTTYCAYCARAARGTNGCNTTYGAYGGNYTNTGGGTNGAYATGAAYGAR ATHACNAGYTTYACNGAYGGNTCNGTNCAYGGNTGYCCNAAYAAYTCNAGYYTNGAYMGN CCNCCNTAYYTNCCNGCNGTNMGNAAYGGNGCNYTNTAYMGNCAYACNATHTGYCCNTCN GCNMGNCAYTCNATHGCNTCNCAYTAYAAYGTNCAYAAYYTNTAYGGNYTNTAYGAYGCN GTNMGNACNAAYAARGCNYTNCARGTNATHMGNCARMGNMGNCCNTTYGTNATHTCNMGN TCNACNTTYCCNGGNCARGGNCARTAYGGNGGNCAYTGGTCNGGNGAYAAYAARGCNTCN TGGTAYGAYYTNTAYAARTCNATHTCNGCNATGYTNCAYATGAAYATGTAYGGNGTNCCN GTNACNGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGYTNACNATHACNGAYTTYATHAAYATHYTNAARCARTAYTAYAARAGY TCNGARCCNAARATHGARGARYTNGARGAYCAYAARATHTCNACNTGGMGNGARGTNYTN AARGARAARCARAARCCNTTYGTNTCNATHTGYCCNGAYAARAGYYTNTTYGAYGCNGTN AARACNYTNGTNGAYAAYMGNGTNCAYMGNYTNCCNGTNATHGAYGARACNACNGGNAAY GCNYTNTAYATHYTNACNCAYAARMGNATHYTNMGNTTYATGCAYYTNTAYTTYAARGAY YTNCCNCAYCCNGCNTAYATGAARCARTCNATHAARGARYTNGGNATHGGNACNTAYGAR AAYGTNATHACNGCNTCNCCNGAYATGACNYTNATHAARGTNYTNCAYYTNTTYTCNGAY CAYMGNATHTCNGCNYTNCCNGTNGTNGAYAARAGYTCNGGNATGATHGTNGGNATHTAY GCNAARTTYGAYGTNATHAAYYTNGCNGCNGARAARACNTAYAAYAAYYTNGAYATHACN YTNCARGARGCNYTNAAYMGNMGNTTYGARACNAAYCAYCARGCNGGNGARAARGTNGTN TCNTGYMGNTCNTCNGAYTCNYTNGARGAYGTNGTNAAYAARATHGTNAARGCNGARGTN CAYMGNYTNGTNGTNGTNGAYGARAGYGGNGGNGTNGARGGNATHATHTCNYTNTCNGAY YTNYTNAAYTAYACNGTNYTNMGNCCNATHGARGARGTNTCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARGCNGCNGARATGAARATGTTYGGNAARYTNACNMGNGAYGARTCNGAR TGGCAYCCNGAYAARYTNYTNTGYMGNMGNTTYAAYGTNCCNAAYCCNTAYCCNGGNTCN GAYATHGTNGGNYTNCCNAAYGTNAARMGNGAYAARTAYTCNATHTTYAAYTTYYTNACN GTNGGNGAYTTYCARGCNAARGARCCNCCNTCNGTNCCNGARTCNGTNTCNAARGAYGTN TCNAARCARCCNGAYAARGAYGCNCCNGGNCCNGGNMGNCCNGGN------AARAARAAR GCNACNYTNGCNTCNATHTTYAARGTNYTNGAYGAYCCNGAYTTYCAYAARCCNATGACN CCNAARGAYTCNAARAARGAYATHTCNGARCCN---------------GARAARCCNGAR ACNGAYGARGGN------------GAYGARGARTCNGARGCNGAYAAYGAYYTNTTYMGN GCNATHTTYAARAAYTCNGAYTCNGARGAYTCNGARGARGARAARTCNGARMGNAARGAR GGNGAYGAYTCNATGAGYGAYGARGAYGAYAAYAARAAYGARGARGARAARATGGAYAAY ACNGARATHTCNTCNCCNGAYGAYGTNACNACNCARAGYGAYAARGTNTTYATGGAYACN GARGARGCNAGYGAYGGNCAYYTNGGNATHYTNCCNAAYGARGARMGNGGNGAYYTNGTN ACNCCNTCNAARTCNTCNACNGAYAARTCNGCNATHGTNAAYCCNTTYGCNAGYGTNGTN MGNGAYCCNGGNATHAARTCNMGNMGNTCNGARTCNMGNTGGGGNCCNAARTCNATHTTY AGYGTNYTNGAYGARATHAAYGARGARGTNAAY--------------------------- ---TCNCARAARGCNATGGGNAAYGARGARGAYACNTCNGAYYTNTAYGGNCCNGCNYTN CCNCCNCCNYTNGARTCNMGNTCNACNCCNACNGTNTCNGARGGNGARMGNGGNGTNAAR AARCAYCARGARAARCARMGNCAYCAYMGNCAYCAYCAYAARGARAARCAYCARAARCAY AARAARGARAARAARAARAARTCNAARCAYAARAARGAYAARAARCAYAARAAR---AAY AARAARTCNTCNAARTCNAARAARGARAARGTNGARAGYTCNGGNAGYGAYGCNGAYTCN GARACNAGYGARGAYTCN---GTNTCNGGNGARGARYTNYTNGAYMGNTTYAARCARGTN TCNMGNYTNAARTCNGGN---------GTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGTNAAYAGYMGNMGNYTNCARMGN YTNCCNCCNTCNGCNGARGCNYTNYTNYTNGARGTNCCNAARAARTGGGARAARCAYGGN GAYYTNATHATHYTNCCNGCNTCNGCNTTYATHTCNTCNCARTGGCAYCARYTNGGNGAR GARYTNTGGYTNACNGTNGCNTCNGCNYTNGGNTGYAARMGNYTNTCNCARCAYTCNCAY GTNGCNGAYGAYGGNTTYMGNTCNCCNCARGTNTCNATGYTNYTNGGNCAYAAYGGNACN GTNGTNCAYGTNGAYAAYGGNATHMGNTGYAGYTTYGAYGTNACNAARTGYATGTTYAGY TCNGGNAAYATHAGYGARAARYTNMGNGTNGCNAGYTGGGAYTGYTCNAARGARACNGTN GTNGAYYTNTAYGCNGGNATHGGNTAYTTYACNYTNCCNTAYYTNGTNCAYGCNAARGCN TGYCAYGTNCAYGCNTGYGARTGGAAYCCNGAYGCNGTNGCNGCNYTNMGNAAYAAYYTN GCNYTNAAYGGNGTNGGNGAYMGNTGYACNGTNTAYGARGGNGAYAAYMGNAARYTNAAR YTNTCNTGYGTNGCNGAYMGNGTNAAYYTNGGNYTNATHCCNAGYAGYGARGAYGGNTGG CCNGTNGCNGTNMGNGTNYTNAARCAYAGYGGNGGNGTNYTNCAYATHCAYGCNAAYGTN ACN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CAR GCNGARAARGAYGARMGNAGYGCNGARTTYAAYGAYACNAARGCNAARATHTGYAGYYTN TAYAAYGARATGGARACNGAYCCNGARACNTCNTTYGCNCAYGAYGTNGTNTGYGARGAY GCNGAYACNTTYACNYTNTCNAGYACNAARATGAARAAYYTNMGNGTNYTNCAYGARGAR YTNGAYGARAARAAYAARAARATGACNYTNGARGTNGARGAYYTNTGGGAYMGNYTNMGN GCNYTNTGGAAYMGNYTNGARACNTCNGARATHGAYAARGARGCNTTYTCNGGNGAYAAR AAYGGNCAYGGNAARAARGTNATHTCNGAYATHAARGCNGARATHGCNGCNTGYGARGAR YTNAARYTNCARAAYATHCARAARTTYATHGARGGNATHMGNACNGARYTNGTNTCNTGG TGGGAYAARTGYTTYTTYGAYCCNGCNCARMGNAARAGYTTYACNYTNTAYTAYGARGAR AAYTTYACNGARGAYYTNYTNGAYGCNCAYGARCARGARYTNGARAARGTNMGNGARTAY TTYAAYCARCAYMGNGAYATHYTNGARAARGTNGCNMGNMGNGARGARYTNTTYAARATH ATGGTNGARTTYGAYTCNAARGCNAGYGAYCCNAARMGNTTYTTYAAYGAYMGNGGNGGN AARYTNYTNCARGARGARAARYTNMGNAARAARATHYTNAARGAYYTNCCNAARATGGAR GAYGARGTNACNGAYTTYATHGCNCARTGGGARCARACNAAYAARAARGARTTYCAYGTN AAYGGNYTNMGNTTYCCNCARTAYGTNATHMGNCAYTGGGARGAYTTYCAYMGNCAYAAR GARCARGARAARCARCAYMGNATGAARGTNMGNGCNAARCARACNCARGARGARATHATG TTYGGNAGYAARTCNGCNYTNGCNACNCCNGGNAARMGNAARYTNGGNGCNACNACNACN CCNATGMGNACNCCNYTNAARGCNMGNAARYTNAAYGGNCCNGTNAARACNCCNAAYACN ACNAGYMGNYTNCCNAAYAGYAGYMGNATHCARCAYAGYACNYTNYTNCAYTCN---CCN ATGTAYACNCCNAARACNCCNYTNACNACNTCNAAYAARAARMGNMGNTCNATHMGNYTN ATGAARAARTCNGCNACNGARMGNMGNAGYTCNAAYTCNAARMGNMGNMGNTCNMGNGAY ATHTTYTCNCAYACNACNATHAGYAGYGAYAAYAAYACNACNTCNTCNYTNGCNTCNACN TGYTCNTAYAAYGARTTYGCNAAYGGNYTNTCNAARCCNAAYTGYMGNAGYAGYGTNATG CCNAGYATHGARGTNATGGARAARGCNGTNGAYGCNYTNGARGGNATGTTYTGYAARACN GARAARGAYYTNGAYTTYATGTCNMGNAARYTNGAYTAYCARYTNGARAAYATGCARGGN GTNGAYCARAARGTNAAYCCNGTNAARYTNATGAARAARATGGARGTNATHAARGCNGAR TAYGCNAAYATHGTNCARGAYGCNYTNGCNGTNCARGARGCNCARAARGARTTYTCNGAY TAYTTYMGNTCNCARYTNYTNACNYTNACNGAYGTNYTNAARAARYTNGARATGAAYACN GGNCARTCNTCNGAYCARGAYGARTCNACNAARGARGTNTTYGAYCARYTNTCNAAYYTN YTNGGNATHCCNCCNGGNGARYTNGARGCNCARGCNAAYGCNGTNAGYGGNTCNTGYCCN GGNTCNTCNTCNACNGARGCNGCNGTNCCNTCNAAYAAY------------------MGN AARTCNGCNAARGARACNGAYAARACNAARTCNGARTTYTCN---------ACNGCNGCN GAYAARMGNGCNAARACNGGNGARTAYTGYGARGTNTCNGARGARGARTTYAARTCNGTN TCNCARYTNYTNACNAARMGNYTNAARYTNGARGAYGTNAAYCARGTNTAYMGNTGYATH TGGCARCAYTTYAARGARGARAARAARATHACNAARYTNACNCCNAARGARATGAAYGCN AARGGNYTNMGNGTNACNGGNGCNACNGGNGARGCNAARYTNAARGTNYTNMGNTCNYTN AARYTNTGYCARATHAGYAARACNGGNGAYGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AARATH TTYCCNAAYGTNCAYYTNTCNACNGGNTGYGGNGTNGAYYTNACNYTNTAYYTNATHAGY GGNYTNATHYTNYTNYTNTCNACNATHACNYTNTTYGARTAYGGNTCNCAYTAYTTYCAY GARAARTCNAARATHGTNGARMGNAAYCAYGTNACNGAYACNTTYATGAARMGNACNGTN ATHGTNAAYAGYGGNTGYCARGGNTAYATHCCNCAYTCNTGYGCNATGGGNGCNYTNGTN GCNTTYGCNATHTGYAARGGNCCNYTNATHTAYGAYYTNGTNCAYYTNATGMGNYTNACN AGYGAYGARYTNATHGTNTCNAGYGTNATHTGYGARGTNTGYTAYATGGTNACNTGGGTN ATGYTNTGGTTYGGNYTNACNYTNAARCARAARTGGAARTTYMGNATHYTNGAYTAYGTN ACNYTNMGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNYTNGGNCARGTNTTY TTYGAYATHCARTGYGCNAAYYTNGCNMGNAARYTNYTNGGNCARCAYATHGTNMGNTCN ATHGGNACNCARMGNATHAARGGNMGNATHGTNGARACNGARGCNTAYCARGGNGARGAR GAYAARGCNGCNCAYAGYTAYAARGGNAARAARACNCCNMGNAAYGARGCNATGTTYATG ACNCCNGGNACNAGYTAYGTNTAYAAYATHTAYGGNATGTAYTGYTGYYTNAAYATHTCN AGYCARGGNGAYGGNGCNGCNGTNYTNATHMGNGCNYTNGARCCNGTNGARGGNCARGAY YTNATG---------CARGARGGNMGNMGNCARAARAAYGARAAYAARAARCCNYTNAAR GARAARGAYYTNACNAAYGGNCCNTCNAARYTNTGYCARGCNYTNCAYATHTCNAARAAY GAYTTYAAYAARGTNGAYYTNACNTCNTGYGAYTCNATGTGGYTNGARAGYGGNGAYAGY GTNGAYGAYAGYGCNATHGTNTGYTGYCCNMGNATHAAYATHGGNTAYGCNGAYGAYTGG AARGAYAARCCNYTNMGNTTYTAYGTNYTNGGNAAYTCNTCNGTNAGYGTNAARGAYAAR AARGCNGAR------AGYGGNCARAARGGNYTNATGGTNTGYTAYTAYACNAAYTGGGCN CARTAYMGNCARGGNYTNGGNAARTTYACNCCNGARGAYATHGAYCCNCAYYTNTGYGAY CAYTAYCAYTAYGCNTTYGCNAARYTNAAYGCNAAYAAYACNATHGCNGCNTAYGARTGG AAYGAYGARAGYACNCCNTGGATGACNGGNATGTAYGARAARTTYAAYAAYYTNAARAAR AARAAYCCNAARYTNAARACNATGYTNTCNYTNGGNGGNTGGAAYYTNGCNTCNAGYCCN TTYACNGARATGGCNGCNTCNMGNGARACNMGNAARGTNTTYATHGAYAGYGCNGTNGCN TTYYTNMGNAARTGGAAYTTYGAYGGNYTNGGNGTNGAYTGGGARTAYCCNGGNTCNMGN GGNAGYCCNCCNGGNGAYAARGARMGNTAYACNYTNYTNYTNCARGARACNATGGCNGCN TTYGARGCNGARTCNCARAAYTCNGGNCARGCNMGNYTNATGYTNTCNGCNGCNGTNTCN GCNGGNAARGAYACNATHGAYGCNGCNTAYGARGTNACNAARATHGCNAGYACNYTNGAY TAYATHGTNYTNATGACNTAYGAYTTYTTYGGNGCNTGGGAYAARTAYACNGGNYTNGTN AGYCCNYTNTAYCCNCCNAAR---MGNGCNATHGGNYTNGAYGCNATHTTYAAYGTNCAR TAYGCNACNAAYTAYTGGGTNAARAARGGNTGYCCNAARGAYAARYTNGTNGTNGGNGTN ATHTCNTAYGGNMGNTCNTTYACNYTNGCNAAYATHTCNGAYACNGGNYTNAARGCNCCN GCNATHGGNCCNGGNMGNMGNGGNCARTAYACNGGNGARGCNGGNTTYYTNTCNTAYTAY GARGTNTGYAGYATGATHAARCARGGNGGNAARATHGTNMGNYTNGARGAYGARAARGTN CCNTAYYTNGTNYTNGTNAAYCARTGGGTNACNTAYGARGAYCARACNAGYYTNGGNATH AARGCNGGNTTYATHMGNGAYGGNGGNTTYGCNGGNGCNGCNATGTGGGCNGTNCCNYTN GAYGAYTTYGARGGNACNATGTGYGGNGARGGNCCNTAYCCNYTNYTNTCNCAYTTYTCN AARACNYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CCNAGYCCNMGNAARGTNYTNYTNCAYAAYATH GAYATHYTNCAYAARAARGCNGGNMGNMGNYTNTAYAAYGAYACNTTYGAYACNMGNATH MGNGCNGCNATHMGNGTNGGNGAYATGAARYTNATHACNGGNAAYCCNGGNCCNGGNAAR TGGATHCCNGARCCNCCNAGYGCNTCNGARGCNCARGAYCCNATHGAYAARAAYYTNTGG YTNTTYAAYATHACNGCNGAYCCNACNGARCAYTTYGAYYTNTCNAGYAARATGCCNGAR GTNGTNYTNAGYATGYTNAARCARYTNGARGCNTTYAAYAARGGNGCNGTNCCNCCNMGN TAYCCNCCNTAYGAYCCNAARAGYAAYCCNGCNYTNCAYGGNAAYGTNTGGGGNCCNTGG ---------------------------------------------AAYGTNTGGGARTCN AGYGTNATHACNCARCCNAARAAYAARACNTAYGTNATGYTNACNGTNGGNGTNMGNAAR CARTGGGTNAAYYTNTAYYTNMGNAAYGAYGTNGGNGARGAYACNGCNGARAARAAYATH GARYTNCCNYTNYTNAARYTNATHCCNGAYGGNGAYATHGTNTAYGARCCNGGNCAYAAY GTNACNTTYGARATHGTNCAYCCNGTNATHMGNMGNTCNGGNCCNAGYAAYGAYAAYAAY GARTAYTAYYTNGTNAARCCNGGNGAYAGYACNACNCCNTTYAAYGTNGAYGTNGARGAR ATGAARAAYTTYYTNCCNACNCCNACNGARAAYAARTTYATGGAYACNACNGARYTNACN ATHGARYTNAAYACNGCNGARYTNCARTAYTCNGGNGTNTTYTCNTTYACNYTNGGNATH AAYAGYCARACNGGNYTNGCNGCNMGNATHGARAARGGNACNGARAARGTNYTNMGNCCN TCNACNCARMGNGGNCCNTTYCCNGARGGNTTYTTYGAYGCNCCNAAYGGNATHTAYGAR AARTTYTGYGGNTAY---------------------------GGNAARTCNTGYATHYTN GGNTGYGAYTTYATGGGNAGYGAYYTNACNAAYYTNGARYTNTTYAARACNGTNGAYGAR GARACNACNAARGARGARATHCARGTNATHGGNGAYGAYATGGCNAAYCCNTAYMGNYTN TCNACNYTNAARCCNCARCAYGGNGAYACNTCNCCNGTNACNTTYACNTGYYTNGCNACN AAYGCNCARGGNGGNAGYAARACNGTNAARCAYGTNTAYACNTTYGGNACNGAYATHGAR TTYATHAARGAYGARACNAGYYTNGARAARTTYGAYAAYGGNACNGCNAARATHACNTGY ACNGTNMGNGCNTCNCCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGYCARAARYTNGTNGAR GARYTNTCNCAYTTYGARGAYTGYCCNTGYCCNAARGGNMGNCCNAAYACNATGTCNAGY TAYGGNATHTCNYTNGAYGARATGGGNATGTCNGCNAGYYTNYTNGGNCCNYTNATHYTN GARTTYATHCARCCNYTNTCNGCNGCNYTNTTYGARCAYTGGMGNACNGARAARYTNGAY TCNTTYMGNGCNTTYTCNGTNYTNTAYGGNCCNGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARGGNMGNAGYGGNAGYGTNATGTGGTGGGGNGCNGARAAY GTNGTNAARTTYGTNMGNCCNACNTAYCAYATGCCNYTNGAYTCNAARGTNGAYGARGTN TTYAARYTNAARACNATGGTNAAYTGGTTYGTNAAYGARTAYCCNATHAAYYTNGGNYTN YTNTAYTTYAAYGGNCCNGAYCAYYTNGCNCAYMGNTAYGGNCCNGAYTCNATHAAYGTN ACNMGNGARATHGCNMGNGAYGAYCARYTNYTNGGNATHYTNYTNGAYGARYTNGARAAR GTNGAYATHYTNGAYGAYATGAAYATHATHGTNACNTCNGAYCAYGGNTTYGCNTCNGTN TCNCARGAYMGNYTNATHCAYYTNGAYTCNTTYATHGAYMGNTCNACNTAYMGNATHATH CAYTAYACNCCNGTNGCNACNATHATHCCNAAYCCNGGNTTYGARGAYAAYATHTTYCAR AAYYTNAGYAARGCNGCNCCNGAYAAYCAYTTYAARGTNTAYAARAARTCNGAYATHCCN GARMGNYTNCAYTAYAARCAYAAYAAYMGNGTNCCNGCNATHGTNGCNATHGCNAAYYTN AAYTGGTCNTTYATHTCNGGNATGCCNGAYGARAAYTTYACNYTNGCNGGNACNCAYGGN TAYGAYAAYGAYTAYGAYGARATGMGNCCNTTYTTYATGGCNATGGGNCCNTCNTTYAAR TCNGGNTAYMGNATGGARTCNTTYGAYAGYATHAAYATHTAYGCNYTNATGTGYCAYYTN YTNCAYYTNAARCCNAAYGCNAAYAAYGGNACNGTNACNAARYTNACNCARATGTTYCAY GGNCAYGARAAYACNGTNTGGACNTTYGGNACNTAYATHATHTGYYTNATHGTNATHGCN AGYGTNGGNGGNGTNTTYGTNGTNGCNGCNTGYMGNCARCAYMGNTAYYTNAARMGNAAR YTNAGYCARYTNAAR------------------GAYTTYTCNATHTGYTCNACNTGGGAY GGNACNTGYATHTCNCAYGGNCCNGTNCARGTNTCNYTNAGYCARTCNTCNAAYGGNGAY YTNCARATHAAYGTNGAYGCNCCNTTYTTYAAYAGYCCNGCNAARCCNGAYGGNCCNGCN GGNCARCCNTTYCCNCARYTNTGGGAYTAYGARGTNGTNGARGCNTTYTTYYTNAAYGCN CARGAYCARTAYYTNGARGTNGARYTNAGYCCNCAYGGNCARCAYYTNYTNYTNYTNYTN AAYGGNMGNMGNAAYGCNGTNAARCARCARYTNCCNATHAAYTAYACNGCNACNATHGAY GCNGAYCAYTGGGCNGGNGARGCNACNATHCCNMGNTCNTAYYTNCCNCCNGGNGTNACN MGNTTYAAYGCNTAYGCNATHCAYGGNGARGGNGARGCNMGNCARTAYGARTCNYTNTAY CCNGTN------ATGACN---------GAYGGNATGCARCCNGAYTTYCAYMGNYTNGAR YTNTTYCARCCNYTNGAYATGTCNTCNYTNYTNAARGAYTAYAAYCCNTCNCARGTNTCN GCNYTNTGG--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARGARGARAAYGAYACNGAYAAYGGNACNTAYACNATHGARGCNGAYGCN MGNCARMGNCARAGYATGMGNAARCCNGCNCAYATGGGNATHGGNGCNMGNCCNAARACN TCNMGNGGNMGNCARACNTTYCCNCARCCNGCNTAYACNGAYCARACNGCNACNAARAAR ACNACNAARCCNAARMGNCAYACNCARAGYAAYCARMGNGARTCNAARGTNMGNCARGAR AAYTAYMGNTCNGCNGARGAYYTNATHCARGARGAYGARGTNAARGGNMGNAAYGCNGAR TGGTTYMGNYTNATGGARAGYMGNYTNAAYAAYYTNAGYTCNTCNGTNGARTCNYTNGTN AARAARYTNGAYTCNGGNGGNMGNCARYTNAGYGTNTCNYTNAGYCARGARAAYACNTCN CCNCCNATGCARGARCARATGCARCARYTNCARAAYCARTCNATGATGYTNAGYTTYAGY CAYATHGTNCARTCNYTNGCNMGNCARCARGGNGAYATGCARCAYATGCAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TGYAAYCCNAGYGAYGCNTAYCARGTNYTNATH ATGGGNTGGYTNAAYMGNMGNGTNGCNGCNACNTCNATGAAYMGNGARAGYTCNMGNTCN CAYGCNGTNTTYACNGTNACNATHGARTCNAARGARGARGTNGAYGGNGTNCARAAYATH MGNACNTCNCARYTNAAYYTNGTNGAYYTNGCNGGNTCNGARMGNCARAARGAYACNAAY ACNGTNGGNACNMGNYTNAARGARGCNGGNAGYATHAAYAARTCNYTNTCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYGAYCCNMGNAARMGN AAYTTYTCNGARGARGARYTNAARCCNCARCCNATHYTNAARAARTCNMGNAARATHTTY GTNCCNGAYGARYTNAARGAYGAYAARTAYTGGGCNMGNMGNGTNAARAAYAAYTGYGCN GCNAARMGNTCNMGNGAYGCNMGNMGNGTNAARGARAAYCARATHGCNYTNMGNGCNGCN TAYYTNGARAARGARAAYAARTGYYTNMGNGAYGARATGTCNAARYTNMGNAARGARAAY GCNAARYTNAARACNGTNGTNGAYAARTAYGARCCNGARACNGCNGCNGCNGCNGCNAGY ------------------------GTNYTNCARGAYCAYCAYCARACNATGTCNGCNATH CCNYTNAGYMGNCARCCN---AGYACNCARACNYTNGARAAYGTNGAYGCNMGNTTYATH AAYCAYACNAARGCNATGCAYMGNATGGGNGCNCCNCAYAGYCAYAAYMGNMGNGCNCAR TCNGCNAARATHMGNCCNMGNACNGCNGCNAARGAYCARGTNAARGCNATGGAYATHTCN YTNMGNGARYTNGTNGGNGAYGTNCCNTCNAGYGGNCAYTTYGTNGAYACNGARGGNYTN GGNGARMGNACNACNATHACNCCNTTYCARACNAGYMGNMGNMGNCCNCARACNTCNCAY GTN---MGNCAYGTNCCNAAYACNTAYAAYGAYCCNAGYMGNTAYACNAARGGNGAYYTN TAYGARGTNMGNGARAGYGAYGTNGTNAARMGNCARMGNCCNGTNAGYGCNTCNAGYYTN MGNGARGGNGAYTCNYTNMGNTCNMGNCCNMGNTCNGGNTCNTAYGGNAARMGNGAYAAR GGNGCNCCNACNTTYYTNACNCARAARAAYGARMGNTCNYTNAARTAYGARTCNACNAAR CCNGTNTAYGTNCAYCCNAAR------CAYGGNAAYCCNMGNMGNAAYTCNGAYGGNCAR GTNACNAARYTNACNMGNTCNAAYAGYCAYCCNGGNYTNATGTCNCARACNGAYATHTTY AGYGCNTCNAGY---------------GCNGTNAARATGAAYTCNGCNAGYAAYAARGCN GTNCARGARAAYTAYGGNAAYGARAAY---------------------GTNGAYGGNGGN AAYGGNTAYGARGAYGGNTAYGCNAGYCCNGARATGGAR---CCNGCNATHCAYACNAAR CCNCCNATGTCNATHMGNGTNAARTCNGCNCAYACNMGNMGNCCNGCNTAYATHGAYAAR TTYGCNGAYGARGARMGNGCNYTNMGNGARATGGARGCNGAYTTYAARAARACNGCNYTN ACNYTNCARAARAARYTNGGNATHGARGARACNGGNATHATHGCNYTNGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGGCARGGNACNAARGCN GTNMGNCCNCARGCNGCNCCNGTNCCNYTNGARTTYGTNYTNCCNAAYGARYTNAARYTN GGNATHGARATGGCNAARAARATGTAYAARGARYTNCARAGYTCNGCNACNTGYAARATH TTYAARTAYGARAARTAYGGNAARTCNTAYYTNAARMGNATGAARGTNCAYCCNGAYGCN CAYTGYCARYTNTCNYTNCAYYTNACNTAYTAYACNYTNTAYGGNMGNATGGCNCCNGCN TAYGARACNGCNCCNATHAARCARTTYTAYCAYGGNMGNACNGARACNYTNMGNTCNTGY ACNATGGARGCNTTYGARTGGTGYAARAGYATGTCNGAYTCNTCNTGYTCNAAYGCNMGN MGNTGYGARYTNTAYGCNAARGCNGTNAARAARCAYAAYACNAARATGGCNGARGCNTGY GARYTNMGNGGNTGYGAYMGNCAYYTNATGGGNYTNGCNYTNYTNGCNAARGARGARGGN YTNCCNYTNCCNGTNYTNTTYCARGAYCCNGCNTTYGTNAARAGYGGNGGNGGNGGNAAY TTYATHYTNTCNACNAGYACNATHGGNTAYACNTCNGTNATGGGNGGNGTNYTNCCNATG TGYGARAAYTGYTAYGGNTGYTTYTAYMGNATHAAYGAYAAYYTNYTNACNTTYTTYATH TCNACNTGGAAYGCNGAY---GAYACNGAYATHGARGTNTTYTCNAGYCARYTNGGNAAR AGYYTNGAYMGNATGAARGAYATGATGGAYCAR---ATGGCNAGYACNAAYGCNMGNYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR AARCCNGGNATHTAYATHCCNGGNCARGGNCCNTTYGCNGCNGCNCCNCCNGGNTAYGCN GCNGCNCARGTNYTNCCNAAYGGNYTNACNACNMGNTAYGGNCAYGCNCCNCARGCNTAY GCNGTNGTNTCNACNCCNGGN---------------------------AGYCAYCCNGCN TAYGCNGCNTAYTCNTCNATGCCNGGNATHCCNACNTCNAGYCAYACNTAYATHCCNACN GCNCARTAYCCNGCNGGNYTNAGYTAYCARACNGCNGCNYTNGCNGGNMGNTCNGGNCCN CCNGCNCAYTAYACNYTNCCNATGCCNGCNCARGCNGGNGCNCCNATHTTYGCNGCNGGN TAYTCNCCNGTNCCNGCNGGNATHCCNGGNGCNMGNTCNYTNCCNYTNGCNCCNGTNGCN ACNGCNGCNGGNTAYCCNCCNGGNTAYGGNTAYCCNGCNGCNGCNTCNGARGGNAAYCCN CCNATGGGNAARGCNATHYTNATHYTNCARACNGGNGGNACNATHGAYAARMGNTAYCCN CARGGNCCNGGNGCNTAYGCNTTYGARTTYGGNGARCCNGCNGTNGARAAYATHYTNGCN MGNATHTGYCCNACNTTYYTNTAYACNATHGARTGYATHTGYACNAARGAYAGYCARGAR ATHACNGAYATHGAYMGNGARGAYATGYTNMGNGCNGTNGTNGARGGNGAYCARGARYTN GTNYTNATHACNCAYGGNACNGAYACNYTNTGYGAYACNGCNMGNTAYYTNGTNMGNGCN GGNGTNGGNCARGGNTCNCARTTYGGNCCNGGNGTNGGNGARAARACNGTNGTNYTNACN GGNGCNTTYAARCCNGARGTNATGAARGAYACNGAYGCNGAYTTYAAYATHGGNTTYGCN YTNGGNYTNYTNCAYGCN---TCNCCNCCNGGNGTNTTYGTNGCNATHGARGGNAGYATH YTNGAYGGNAAYCAYGTNATHMGNTGYGARGAYGGNAARTTYGCNGAYGAYMGNTAYGTN YTNAARMGNTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATHGGNATGTGGTTYGAYATHYTN CARYTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGYTNTCNMGNTCNGGNMGNGCNGARACNMGNAGYMGNGCNAARGAR GAYATHAARMGNGTNATHAAYGCNATHGAYAARGTNMGNAARTGGGARAARAARTGGGTN ACNYTNGGNGAYACNTCNGTNACNATHYTNAARTGGGTNCCNGTNACNGCNCARGARAAY CCNGGNGCNYTNMGNAARATHCCNGGNGTNAARACNAARACNTAYTCNAARGCNMGNGTN GARMGNGARMGNGARYTNTAYGCNGCNGARACNAAYGGNATGCCNMGNGCNAAYTCNCCN TCNAGYAAY---------AAYACNAAYYTNTCNAAYACNAGYTCNCCNTCNTCNAAR--- ---AAYAAYAAYGGNGAYAARCCNAARAAYGGN------ACNGGNACNAGYAGYCARGTN GTNTAYTCNGARGARAAYACNCARCARTCNATHGGNTCNTAYGGNTCNGARAAYYTNAAY GARGAYTCNAAYATGTCNTTYCCNGARAAYAGYGARYTNAGYGARCARGCNGAYCAYAAY GARTTYTCNCAYGAYAGYAAYGAYGCNGAYCCNGGNATGMGNGTNGCNATGAGYATGGTN GGNGAYGARGARGARACNAARCCNGAYCARGARAGYCARAAYGTNGARTCNACNCCNAGY GARCCNGAYAARGARTCNTCNTCNGARGARCCNCCNATGAARAARACNAARACNGCNTCN ATGACNGARAARCAYGAYTTYGGNGTNGCNCCNATHACNTGYCAYGCNTTYAAYAARGAR MGNAGYGGNYTNGCNATGTCNYTNAAYGAYTCNAAYGTNAARATHTAYAAYAARTCNGGN GCNAARTGGGAYGARGTNGCNACNYTNATHGARCAYGCNCARMGNGTNACNAGYATHGAY TGGGCNCCNAAYAGYAAYMGNATHGTNACNTGYTCNGCNGAYMGNAAYGCNTTYGTNTGG ATGYTNGARGAYGGNAARTGGAARCARGTNYTNGTNATHCCNMGNATHAAYMGNGCNGCN ACNTGYGTNAARTGGTCNCCNMGNGARGAYAARTTYGCNGTNGGNAGYGGNTCNMGNYTN ATHGCNATHTGYTAYTAYGAYAAYGARAAYAAYTGGTGGGTNAGYMGNCAYATHAARAAR CCNATHMGNTCNACNGTNACNTGYYTNGAYTGGCAYCCNAAYAGYGTNYTNYTNGCNGCN GGNTCNACNGAYTTYAARTGYMGNGTNTTYTCNGCNTGYCARAARGARGTNGAYGGNAAR CCNGCNCCNTGYTCNTGGGGNACNAARATGCCNTTYGGNGCNYTNATGGCNGARTTYAGY AAYGGNGGNGGNGGNTGGGTNCAYTCNGTNTCNTTYTCNCCNAGYGGNCARYTNGTNGCN TGGGTNGGNCAYGAYTGYAGYGTNTCNATHGCNGAYTCNACNAARAAYAAYGARYTNGTN GTNGTNAARGARAGYTTYYTNCCNTTYATGAGYATHTCNTGGGTNACNGARAAYACNGTN GTNGCNGCNGGNTAYGAYTGYAAYCCNATGGTNTTYTCNTTYAAYGGNGGNAARATHACN TCNCARGGNAARYTNGAYGTNCCNCARYTNAARGARACNGGNACNATGAGYGCNATGAAY MGNTTYAARAAYYTNGAYAARAARGCNACNGAYAGYGAYACNTCNCCNGARAARTCNACN CARCAYCARAAYACNATHACNCARGTNTCNATHTAYACNGGNGAYAARACNAAYGCNTCN AARATHGCNACNACNGGNGTNGAYGGNAAYYTNATHATHTGGGAYYTNAAR--------- ------------------------------------------------------------ ---------------------------------------AARCCNGCNGGNGGNGAYAAR AARATHGARACNAARAARYTNGARTGGAARGTNGARTCNAARATHGGNTCNYTNGAYAAY GCNGGNCAYGTNGCNGGNGGNGGNGAYATHAARATHGARTCNCARAARACNGARTGGAAY GCNACNTCNAARATHMGNTCNYTNGARAARGCNAAYCAYAARCCNGGNGGNGGNGAYAAR AARATHGARACNCARAARACNGAYTGGAAYGTNCARTCNMGNATHGGNTCNYTNGAYAAY GTNAARCAYCARCCNGGNGGNGGNGAYATH------------------------------ ------------------------------------------------------------ ---YTNYTNGGNYTNCCNATGTTYMGNGAYGCNAARACNTCNTGYATHTTYTTYGGNYTN YTNGTNATHACNTAYTAYATHATHATGGAYATHATHYTNTTYATGMGNTTYAARAAYGTN AGYATHGTNGARGAYTCNAARCCNGGNGCNCCNGAYGARATGTAYTCNCCNTTYACNCAY YTNTCNGTNAARGCNYTNATGAAYGAYCAYACNAGYCARTAYATHATHAGYCCNTCNGCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNAARYTNATHGTNTTYGAYYTNGAYTAYACNYTNTGGCCN TTYTGGGTNGAYACNCAYGTNGCNCCNCCNTTYCARATGAARTCNGAYGGNAARGTNTAY GAYMGNMGNGGNCARCAYGTNAARTAYTAYMGNGAYGTNCCNGARATHYTNTCNAARYTN CAYTCNGARGGNTAYAARYTNGGNYTNGCNTCNMGNACNAGYGCNATHGARGAYGGNGAR GCNYTNGTNAARYTNTTYGAYTGGGAYAARTAYTTYCARTTYMGNGARATHTAYCCNGGN TGYAARAARACNCAYTTYGARMGNCAYCAYAARTCNAGYGGNATHCCNTAYAARGAYATG YTNTTYTTYGAYGAYGARCAYMGNAAYATHGTNGARGTNTCNACNYTNGGNGTNACNTGY ATGTTYATHCCNGAYAARGGNGTNACNCAYGARTCNYTNMGNGARGGNYTNGARYTNTTY AARAARAAYAAYAGYGARAGYGGNCAYACNTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TTYATGAAYGARTCNAGYAGYAGYTCNATHAAYAGYTCNAARATHGARGCNGTNGCN GAYYTNYTNAARAGYCCNTCNMGNCAYYTNGTNTCNCARTAYGTNMGNGAYMGNGARGAR TAYMGNATHGARMGNCARGARMGNGCNGARGTNGAYMGNGARMGNMGNYTNMGNGARCAR CARGTNAGYTCNAGYGARGAYGARATHAGYGARMGNTAYGCNGARYTNYTNGCNATGAAR GARGARGARMGNATGMGNMGNMGNGTNTCNAARAARAARAARGGNAARGAYAAYYTNTTY TCNATHCCNGARGAYMGNAGYCAYGAYCCNACNCCNACNAARCCNAGYACNTCNTCNAAR MGNCCNAARCCNAARGTNGCNAGYCARACNCAYGTNATHGAYCCNAAYATGACNAARYTN MGNGAYMGNATHGCNAARCARAARACNAARGTNGAYAARGAYATGYTNAARGARATGCAR MGNATHGARAARYTNAARAARYTNGARAGYYTNYTNATHGCNAARAARAARGGNAARATH TCNTCNGARAAYGAYGARCCNGGNAGYTAYGARGGNCARGAYGTNGCNTCNGTNTCNTGG CAYATHCCNATGGAYYTNCCNGCNAGYCARTGGAARGARCCNCARCCNMGNCCNCARCCN TTYMGNGAR------GTNACNTCNTCNGTNACNAAYAARCCNMGNAARGARAARCAYGGN MGNGGNGTNGGNMGNGCNGCNACNGARAGYMGNAARGARTAYGARGGNATHTGGACNAAR TCNAGYCAYCCNCARGGNATHCCNAARYTNGARTGGGARGARGTNGTNMGNMGNGAYGCN YTNGCNACNAARACNAAYCAYTGGGARGTNGAYCCNATGATGGAYMGNGTNCARTAYATH YTNAAYMGNCCNGCNACNCAYACNGCNAGYGARGAYGCNGAYGTNTAY------GARAAR CCNATHTCNAARATGTCNYTNCARGAYGCNTTYCARATGMGNAARCARAAYTTYATHTCN TCNTGYTCNCARMGNCARAARMGNATGAARYTNGCNMGNGARGAYMGNCARYTNCARGAR TGYYTNMGNYTNGARMGNGARGCNATHTTYGCNGARCARGARMGNYTNGCNCCNGCNAAY YTNTAYGCNCAYCCNTAYAGYGAYAAYYTNTAYCARCCNAARYTNMGNGTNYTNACNAAR CARGARATGAARACNYTNACNGCNAARMGNTAYAAYAARYTNCCNGARGTNATHGGNAAR AARGARGARGAYAARAARAARATHGARGCNAARYTNAAYMGNYTNMGNGCNAGYYTNTTY AAYAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARACNAGYCCNGAYATG TGYAGYTTYYTNGARCAYTTYGARTGYYTNYTNGARAARTCNAARATGATGGGNCARYTN AGYYTNTTYAAYYTNGCNTGYGCNGCNAARGCNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGMGNGTNTTY AARTGYYTNGTNTCNGAYGAYGARATGTTYAAYGAYTCNTAYGAYTTYGARGARAARGAY GGNTTYTAYGTNGTNAARGGNAARTAYGARACN---MGN---MGN---GGNGAYAAYATH GTNATHGCNGGNTTYAAYCCNAGYGCNGARGARGGNGGNGAY---GARGAYGAYCCNGAY TCNGARTCNGGNGTNAAYATHGTNATGGAYCARMGNYTNAARGARACNGGNTTYGGNACN AARAARGARTAYACNACNTAYATGAARGAYTAYATGAARMGNATHTTYGCNAARYTNGCN GARAARAARTCNGCNGAYGARGTNGGNGARYTNAARTCNGGNGCNACNGARGCNTTYAAR YTNGCNYTNAGYAARTTYAARGAYYTNCARTTYTTYACNGGNGTNAAYATGGAYCCNGAY GGNYTNGTNGTNYTNYTNGARTGGGTNGARGCNACNGAYGGNGGNAAYGGNGTNCARACN CCNTAYYTNTAYTTYTAYAARGCNGGNYTNTCNGAYATHAARGGNTCNGTNGGNTGYMGN AGYCARAAYGARYTNATHGAYATHATGAGYGARGTNAARGAYGGNAAYTTYACNATHGAR GARGCNTCNACNYTNTTYAAYGCNTGGAARGARMGNTAYCARAAYGGNGGNGCNGCN--- AGYTTYAARGAYAARAARAAYTCNYTNCAYGARATGMGNCARAARACN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNCCNMGNCAYGCNMGNGARTAYGAYGGNGCNGAYAGYTCNGAYYTNGAY GARAARGAYGCNGAYGGNAAYGTNTCNGAYGARGAYACNGCNGAYGCNAGYGARACNGAR GARAARACNCCNAARTCNCARAARCAYACNYTNCCNAAYAGYGGNAGYCARMGNACNGAR ATHAARGARCARATGTAYCARGAYAARYTNGCNCARATHAARAARCAYATHCARATGYTN GARGARGGNACNYTNCARGARTTYYTNAARMGNACNAARAARATHGARYTNAAYTAYMGN GARMGNYTNMGNGAYAAYGARATHTGYAARAARGTNGAYATHGARAARGCNGARCARAAY TAYYTNATHGAYTGYGARAAYGCNCARAARGARTTYGARGARAARMGNGARACNYTNAAR GARAGYYTNATHAAYCAYYTNAARGARAARAARGTNGAYYTNAARGARACNYTNATHAGY GAYYTNAARGARAARMGNAGYATGATHGARYTNGARMGNCARACNGTNGAYYTNAAYGGN GCNGAYTTYATGGARGTNAARCCNACNATGACNMGNAARYTNMGNMGNMGNCCNAAYGAY CCNATGCCNATHCCNGARAARMGNMGNAARCCNTCNCCNGCNCARGTNAAYATHYTNYTN GAYGAYGAYYTNATHATGGCNGAYYTNMGNYTNATHATGAARGTNAGYGGNAARCCNGTN GCNAARAARCARGGNYTNAGYTCNCARAGYCCNATHATHGAYACNTCNTCNGAYGTNMGN ATHGARGAYGGNMGNYTNTGGTAYGAYAARAARTGGTTYCARMGNAAYTCNATGGTNCAR ATHGAYAAYAARGARGGNGGNTCNMGNATHTGYGGNACNATHACNAAYATHYTNAAYCAR GARATHTGGGTNAARAARAGYGGNGAYAAYTCNAARYTNMGNATHTGYYTNTCNCARTTY GTNAARGGNAARTAYATHATGAARAARMGNACNACN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTCNMGNGCNGCNGCNTCNAARACN MGNGGNGCNGAYAARACNAARCCNCCNGCNTCNCARACNCCNGTNATHGCNCAYGARATH GTNCCNGGNAARTTYAAYGAYAAYGAYTGGAAYGTNATGYTNGAYMGNGAYGGNGGNGAY GARTTYGTNATGGAYATHATGGAYGARYTNATGGARAARACNATGACNACNATHTAYGAR AAYTAYATHGARMGNCARYTNYTNCCNTTYACNATHACNCARGCNMGNGAYGCNATHATH GARATHATHGARTGGCARTTYYTNGCNMGNGAYGARGGNGARGARAAYATHGCNGAYGAY YTNGGNTGGACNCARGAYGARGARCCNGARCCNGCNGARACNGAYTGYTGGGCNCARGGN TCNGTNCCNMGNAAYGTNATHYTNGCNCCNACNCCN------------GTNYTNGARGAR ATHCCNGARGARCCNGARGCN---YTNCCNCARGARGARGARACNGARGTNGARGCNCAR AARGAYGTNTCNCARGARCCNCCNGARYTNGAYGAYGTNGTNTCNGARCCNGARGARACN CCNGARGTNGTNGCNCARCARGAYAARAARGARCARGARGTNGAYAARGTNCCNTGYCCN CCNAARTTYTCNGCNTCNAARTCNAARACNAARTTYMGNCCNTAYMGNGGNAARYTNAAR TCNGCNGGNACNGGNAARATGACNGARTCNYTNGARGARACNGARATGAARATGATHTAY GAYGARATHGTNGCNTCNATGCCNCCNAGYGARGARAARCCNAGYACNYTNYTNAAYATG CCNGCNTCNTGYACNAGYATHYTNAARGTNCARACNGGNMGNCCNCCNGGNAAYAARGAY GTNGTNTAYGAYGAYYTNGGNAAYGTNGTNGCNGTNATGAARYTNGAYCCNGARAARYTN CCNACNCAYAARGTNAGYGTNAARTAYCAYGTNGTNGAYCCNGCNGTNGARGCNGCNCAR GCNMGNYTNGAYGCNATGMGNAARGGNAARTCNACNGGN---AARATGMGNAARYTNMGN YTNAGYAARAAYTCNATHTCNGARGGNGTNACNGGNGGNGCNAARTCNAARGTNTCNTCN ACNAAYAAYACNGTNGCNCCNYTNCCNCCNCCNYTN------------------------ ---------------------------------ATHGARGARATGGARGTNTCNCAYGGN GTNGTNATHMGNGARGGNGGNMGNGTNAARAARGGNCCNGGNMGNTAYTAYMGNAARYTN GAYGTNYTNGARGARCAYCARYTNGGNATGAARCCNGTNAGYGTNMGNYTNACNAAYGCN GGNATHACNGTNAAYGAYYTNYTNGAYMGNAAYACNCCNATHYTNMGNCCNYTNCARGAR TCNTCNCCNYTNCCNCCNATHATHCCNCARCCNCCNMGNCARCCNCARTCNCARGTNTCN ATGTCNMGNATHGCNGTNGTNGGNGCNGGNGTNAGYGGNYTNAGYGCNGCNATHAAYGTN CARMGNGCNTTYMGNAAYTCNAARGTNACNATHATHGCNGAYGGNTTYGGNCCNGAYYTN GTNAGYAAYGGNGCNGGNGGNYTNTTYMGNCCNTAYYTNGGNGAYGTNCARACNGGNAGY GGNGGNGARATHACNAARCARTGYTAYMGNGAYTCNTTYAARCAYTTYAGYAGYYTNGCN ATGTCNGAYAARGCNAARGAYAGYGGNCARACNTTYGTNTCNGGNACNATGGCNTAYAAY GARTCNMGNGAYGCNGGNTAYGARYTNATGMGNGARYTNGCNTTYGAYTTYCAYAAYATH ---CCNCCNAGYGARYTNAARMGNMGNGGNATH---CCNTAYAARTAYGGNTAYAAYTGY ACNACNGTNATHTCNCARATGCCNGTNTAYYTNMGNTGGYTNATGGARCARTTYAARGCN GARGGNGGNACNGTNCARMGNMGNACNYTNAARGAYATHAARGARYTNTAYGGNGAYTAY CARYTNGTNATHAAYTGYTGYGGNCARMGNGCNGARACNYTNYTNGGNGAYAARGARTGY TTYCCNGTNMGNGGNCARYTNGCNGCNGTNMGNGCNCCNTGGATHAARCARTTYTTYTTY TCNGARTCNYTNCARGTNATGCCNCARCCNGAYAARGTNYTNATHGGNGGNGGNATHMGN GTNAARGGNAAYTAYAGYACNGCNGTNGAYCCNGARYTNGARGAYGAYYTNTTYAARMGN GCNGARGCNATHTTYCCNGARTTYAARGGNGCNGARAARYTNCCNGGNTGGGCNGGNYTN MGNCCNGGNMGNACNCARYTNMGNYTNGARTAYGARATHATGGAYYTNGGNAAYAAYMGN AARYTNCCNGTNGTNCAYAAYTAYGGNCAYGTNGGNCAYGGNGTNTCNYTNAGYTGGGGN GCNGGNATGCARTGYGCNAARYTNGCNAARGARGCNATH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GCNTAYGAYTTYGAYGARAAYGARGAYCCN TTYAARTCNAARAARACNYTNGCNAGYTCNCCNCCNTGYTCNCCNAARYTNACNCCNAAR TAYACNGARGAYCARGGNAARTGYGAYGAYGGNATHGAYGTNYTNTCNCCNGARTCNGGN CARYTNCARGGNACNGARCARTCNCCNGARAGYGCNCCNGCNGARAAYAARACNAGYTCN CARGTNACNCCNAARAARAARAARATHATHAARAARCCNCARGCNCARTCNAARTTYAAR CCNCCNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGGMGNYTN GCNAAYATHATHATGGCNGCNTTYTTYTTYYTNGCNTCNYTNGCNAAYAGYAAYGAYAAY GAYTGGTAYATHTGGTCNCCNATGTAYTTYTGYCCNGCNGTNYTNTGYTTYGCNGCNTTY YTNCAYCCNAARGCNATHGGNAAYCCNATHTGGCARYTNTTYACNTCNATHGARTTYGGN YTNTCNGTNGTNATGGGNYTNTAYCARATGGCNACNGTNTTYGGNATGTCNAGYAARATG AARTCNAAYCCNYTNTTYCAYGARGARGGNMGNGARATGGGNGGNYTNATHATHATHYTN GCNTGGACNGGNATHTCNMGNTTYTAYCCNTAYGGNAGYACNACNTCNAARTCNAARAAY AAYYTNATGACNGGNYTNYTNGTNGTNGCNYTNACNYTNGCNGTNGTNCCNYTNYTNACN TGGTCNYTNTGYTTYGTNAGYGAYTGGCAYAARCAYYTNGGNCAYTGYTCNGGNATGTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TAYYTNACNTCNAGYGGNYTNAARTGY CAYGARTGYGCNCAYAAYAAYMGNMGNCCNTTYAARTGYACNYTNTGYTCNAARGCNTTY TAYAGYGCNAAYGTNYTNAARTGYCAYYTNAARATHCAYACNGGNGARMGNYTNGAYATH TGYCAYATHTGYGGNAARTCNTTYATH--------------------------------- ------------------------------------------------GARGGNACNTCN TCNYTNCARATHCAYYTNATGMGNCAYMGNGGNGARAARMGNCAYGARTGYAARATHTGY AARAARGCNTTYATHGARAAYTAYAARYTNAAYACNCAYATGMGNATHCAYACNGGNGAR AARCCNTAYAARTGYYTNGTNTGYCARAARGAYTTYGCN--------------------- ------------------------------------------------------------ ------------------------------------------------------CCNCAR CCNGARAGYGAYAGYGAYGARGAY------TTYGGNAARGGNAGYGGNATHMGNGTNGAY MGNACNAARYTNCARAARYTNAARGARATGTTYCCNGGNGGNGAYGTNAARMGNATGAAR GCNGCNYTNTTYGCNTAYGAYAARGAYTTYGARAARGCNATHGGNTTYGTNACNAAYAGY ACNCCNGGNAARMGNCCNTCNACNGARGAYCARTCNGAYGAYYTNCCNGCNATHACNGGN AGYMGNAARMGNATHAARATHYTNCCNTCNTCNCCNTCNCCNACNAARGARGAYGGNTTY TCNTTYACNACNTCNAAYGGNACNAAYCARGAYTCNGTNAARTTYYTNAARCARTGYTTY CCNCARAARTCNGARGARCAYATHAARMGNATHYTNAARGARAAYGAYGGNGAYGCNGAR AARTCNTCNGTNGCNYTNACNAGYGARGAYAGYGAYGAYGCNAARYTNGCNGCNTCNYTN GCNTCNGARATGCCNGGNACNAGY---TCNAARYTNACNAARGCNGTNAARGARCARAAR ---AAYGGNAAYGCNAARMGNMGNAAYGAYGAYATGAGYGAYGAYGAYGAYGARTAYGGN GAYGARTAYGAYAGYGCNGAYAGYGARGAYAGYGARGAYYTNGAYAAYAARTCNAARTCN GARATHGAYAAYTTYYTNCARTTYTTYGARGARGCNACNGTNGARGARYTNACNGCNATG CCNGGNTGYTCNAARAARAARGCNGARYTNATHATHACNYTNMGNCCNTTYAARTCNTGG GARGAYYTNTGYAAYAARTTYAGYAAYATGAARTCNYTNTCNACNTCNYTNATHTCNGGN TGYMGNGARATHATGMGNGTNMGNAAYATHATHMGNMGNYTNATGGTNMGNTGYGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARACNGAYGCNTCN GTNATHATHGCNAARATHGCNGAYGAYGGNACNTAYYTNGTNMGNAARAGYGARGAYAAY TCNAAYGTNYTNGTNGTNTAYGCNGGNGGNGTNAARAARTAYMGNATHATHAAYCARGAR AAYGGNMGNATGACNYTNTCNGCNAAYTCNCCNGAYTTYGARMGNATHGARGAYYTNYTN TAYCAYTAYTAYAGYACNCCNYTNCCNAGYTGYAAYCARAARYTNGTNTGYCCNTTYAAR YTNCAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGTCNGAYTCNAARTCN AGYYTNGCNMGNGAYGGNACNATGCARGTNACNGCNAARGARGGNATHGAYTAYYTNAAR TCNGCNCAYAARGAYACNYTNYTNAARGCNCARGGNYTNGTNAARGAYAARCCNGCNGTN CARMGNGAYGGNACNATGGTNGCNACNGCNAARGARGCNGAYMGNYTNYTNGAYGGNAAY AARCCNGAYGCNGAYGCNCARACNMGNGGNCARCARAARCARATHGARGAYYTNAARAGY GARAARGCNGARCCNMGNGCNAARAARGCNAARYTNGCNAARGAYGGNACNATGGCNGTN ACNGCNAARGARGCNAARGCNYTNYTNGCNGGNGARAARYTNGGNGAYACNMGNCARGAR ACN---------AARAGYAARACNAARACNCCNYTNMGNAARAAYACNACNATGGCNMGN ACNGTNGARGARGCNAARAGYGTNYTNGAYGGNAAYYTNGAYGTNAGYGARGGNMGNAAR ACNMGNTCNCARAGYMGNGGNGAYGCNCCNAARCCNTCNATGAARAARYTNGGNACNATG CARCARACNGCNAARGAYGGNAARGCNTAYYTNAAYMGNAAYAAR---GGNAARMGNGCN GCNAARGCNGTNGARGARGARAGYGAYGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MGNTCNCAYAAYTCN AGYGAYTCNAGYYTNGARMGNCAYAGYGTNGAYACNAAYGGNAGYGAYGARAAYAAYYTN GCNCCNGARGCNATGMGNGCNCCNTCNTCNMGNYTNCARGCNCCNAAYAGYACNTCNACN TCNYTNCCNAARMGNGGNATGTCNGGNYTNGCNCCNGGNYTNGCNMGNCCNCARCARMGN GGNGCNTCNCCNCARMGNCARAGYGGNYTNCCNACNGCNMGNMGNCARATHGCNMGNCCN TCNACNGCNCCNMGNTCNTCNYTNCCNCARTTYMGN------------------------ ------------------------------------------------------------ ---------------------------------ACNATGGCNGCNGCNACNGCNMGNACN YTN------GTNAARGARATGATGAARCCNCAYGTNCCNATGATHAARTTYCCNAARMGN GAYYTNCCNAARGGNYTNCAR---CCNGGNCAYGTNGTNGGNAAYCCNAAYTCNYTNGAR TCNYTNYTNGCNAAYAAYGTNGGNTCNGGNAGYGCNAGYTCNMGNTCNGCNGGNTCNACN TCNAARGGNCCNTCNATHGAYTCNTCNGARYTNCCNACNMGNTTYCARMGNAARCCNATH TCNGCNGARGARATGGARTTYATHGARAARGGNGGNCARGTN------------------ ---------------------------CCNGCNGARGARAARMGN------GGNATHTGY GTNGARTAYTGYAGYTCNGAYYTN------------------AAYTGYCCNTCNGGNCAR GCNTGYGCNTCNAAYGGNTGYGGNCAYACNTGYCARACNGTNATGGCNGCN--------- ---CCNAARAARTGYTCNGAYGCNATGTGYYTNATGYTNTGYGARCAYGGNTTYAARGAY GGNCCNGAYGGNTGYCCNGTNTGYAARTGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNGTNYTNTGGACNAAYCAYMGNGTNATGGARTGGYTNMGNACNATHGAYYTNTCNGAR TAYGCNCCNAAYYTNMGNGGNAGYGGNGTNCAYGGNGCNYTNATGGTNYTNGARCCNMGN TTYAAYGCNGARYTNTTYGCNGTNYTNYTNTCNATHCCNCCNAGYAARACNYTNYTNMGN MGNCAYYTNACNTCNCAYTTYGTNGGNYTNATHGGNTCNGARACNCARCARMGNAARMGN GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------AGYCAYATHCAYACNCARCCNTCNCCNYTNYTNTTY CARGTNTCNGARAARYTNTGYGCNGARCCNATGAARMGNMGNAARAARATGGAYCCNGCN ATHGCNGCNGCNMGNACNCARAARAARYTNAARMGNATHGAYAARGARATHAARMGNYTN TCNAARTTYGGNAARATHYTNAARCCNGTNGARGARATHGARGTNGAYMGNMGNMGNYTN GARGCNTCNGGNGARMGNAARMGNGARCCNAARGTNYTNACNTTYGARGARTCNGARTCN MGNGCNYTNYTNCAYAARAAYTGGACNTGYTAYMGNACNAAYAARCAYCAYGARATGYTN CARATHTTYTCNAARACNYTNGAYGCNCARGARGARGCNYTNGARGARYTNMGNGCNGAR TCNGARGARYTNTAYYTNGCNGCNATHGARAARGAYGAYAGYYTNYTNCCNYTNACNTTY GAYGGNCCNAARGARACNCCNCCNATHAARGAYTAYGAYGCNCCNGAYGGNGARTAYGTN GAYACNACNMGNAARTTYATGACNATHAGYGGNGAYATGGARTGGAAYATHGAYATGGAR GTNAAYYTNTTYCAYGCNATGMGNGGNCAYAARCCNGCNGGNGTNAAYMGNCAYTTYCAR ATGATHGCNATHCAYGARAARYTNAGYTCNTCNGCNAARAARGTNACNTCNAAYGAYGTN TGGAARCAYYTNTCNACNYTNTAYGAYYTNCARGCNYTNAAYGARTCNGARATHGTNCCN TTYCCNAAYAARAAYGGNGAYTTYGCNYTNGCNGAYAARGARATGYTNGAYYTNTGYACN AARTCNTTYCCNMGNTCNTCNTAYATHAGYACNGTNTCNAGYGAYTCNGTNAARYTNGAR GGNACNGGNAARAAYATHTCNAARYTNAGYAGYAARCARGARATHAARACNCCNAARCCN GARTCNAARAGYGARCAYAAR---------------CCNAGYAGYTCNTCNAARGCNGAY GGNMGNTCNAAYATHCCNTCNAGYMGNTCNGARTCNAARTCNTTYCARCAYAGYAGYAGY GGNAAYGTNAGYAGYAGYAGYTCNAARTCNTCNCAYCAYAAYACNTCNTCNTCNGCNCCN TCNCCNTCNCCNAARMGNACNAARMGNACNMGNAAYGTNAAYTCNGCNTCNGCNAGYCCN GCNACNCCNACNGARCCNCARTCNAARMGNMGNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNGTNGAYCAYYTNAAY GAYCARATHMGNCARATGAARGAYGARAAYGGNMGNYTNTAYAARYTNYTNAGYGARMGN GAYTTYGARYTNMGNCARYTNAARAARAARAARGARGARCAYACNTCNAAYGCNATHGAY YTNCCNATHACNAGYGARACNGCNGCNACNAARATHGTNGARYTNAGYAARAARGTNMGN GARYTNACNGCNGARAARGARTCNGARAARACNMGNTGYAARCARTTYCARAARAARTGY CAYGAYYTNCARATGCARYTNCAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TTYAAYATH ATH------------AGYACNGGNGARGARGTNGARATGGCNGAYCARGAYATGGCNTCN ATHATHTCNATGGARMGNGGNYTNGARGARGARAARACNACNYTNATGYTNAARGTNYTN GCNATHYTNYTNMGNAARAARGCNGARAARMGNGARATHACNCARAAYTTYTGYAAYGAY TTYYTNAARAARACNGARGARGAYYTNAARGAYATGGGNACNATGATHGAYMGNGARAAR GARGARGCNGARGARAARYTNAARAAYGAYCCNAARYTNAGYAARGAYACNCARACNYTN GARACNGARATGCARAARYTNCARACNCARTTYAAYAAYAARCARGCNAARYTNCARMGN GAYTTYMGNGAYAARATHMGNYTNGAYYTNYTNMGNTCNTCNGGNATGCCNGARTCNGAR GTNGARGTNGTNATHGCNGGNYTNATGACNAAYATGGCNCARGTNGARGARAARYTNGGN YTNGARCARGCNMGNCARMGNMGNTCNYTNGARCARMGNYTNGCNAARMGNAARCARGCN GTNGARTAYCARGARATHGARAARCARGARAARGCNAAYGAYCARGAYGARMGNGTNAAR ACNTTYMGNTCNYTNYTNGARAAYCAYACNAARGAYGGNTCNYTNYTNGARAARCARTGY GAYACNGTNGTNGCNGAYTAYGCNGAYGARYTNGAYAARYTNAARAARTAYCAYTCNGGN GARTTYAAYCARYTNMGNYTNGARAARTTYGARYTNYTNCARCARGAYMGNYTNAAYAAY TTYTAYAARYTNAAYMGNAARCAYGAYAARGARAARGCNGCNTTYGTNCARACNGCNGAY AARGCNACNAAYCCNYTNGARTTYATHAARYTNTAYCAYGAYYTNATGACNMGNCARCAY ATGGARAARGARGCNYTNTCNGGNGAYYTNGAYATGMGNGARGTNCARGARATGCAYAAR YTNAARCARGARTGGGAYAARAARGARTGYMGNGCNATGGAYCARGCNACNGARAARYTN GCNGARCARATHGARGGNTCNTCNACNATHACNTCNAARGARGCNGCNAARATHATGAAR YTNCAYAARGCNCARATGGAYCARTAYCAYGCNMGNAAYCARMGNGAYAARCARGCNACN YTNGCNMGNYTNCARGARAARATGCARCARMGNYTNGARGCNGCNGAYGARGCNGARGCN MGNGAYCARAARGARCARGARACNYTNAARGAYCARCARATGGCNACNYTNAGYAARGTN YTNGCNACNAAYYTNGAYYTNTCNGARCARGCNAARGARMGNATHATGMGNGARCAYGAR CARAAYATGCARTCNYTNTCNAAYCARYTNATGMGNAGYAARATHMGNCARCARAARAGY YTNGARATHAARYTNAAYCARMGNAARGCNAARYTNGCNGARYTNAARCARAARCARGAR YTNGGNTCNTCNMGNCCNGGNAGYAGYAARAARGARAARGCNAAYAAY------GARAAY ------ATGGCNACNCARATHGCNAARGARGARGARGGNTTYGARGARGCNMGNATHYTN GCNGTNGCNGAYYTNMGNMGNCARYTNGCNCARGARACNGARGAYGCNYTNAARCARCAR GAYGARGARATHGGNYTNYTNATHGGNMGNYTNCARGTNGGNCARGCNMGNMGNAARGCN ATHYTNGARAARCARGAYGCNGTNYTNAARAAYYTNCARGAYAAYYTNGARMGNCARGTN TCNTCNGCNAGYGGNYTNMGNCCNTCNGTNACNGAYACNATHYTNAAYCARCAYCAYGCN AARGTNTCNCAYYTNAAYGARCARYTNCARMGNCAYAARGAYAAYCAYGARMGNAAYATH YTNGARAARYTNGCNCARMGNMGNGCNGARAARGARCARCARATHGARTCNCARYTNGAR GARGARGCNCAYTCNGARTAYACNGARAARCARAARMGNGGNGCNGGNTAYGCNAGYYTN GCNYTNATGCARTCNTTYYTNGARCARMGNCAYGCNAARGCNYTNAAYGARYTNGARYTN GARATGAARGCNGARYTNGARAARAGYAARAAYGARYTNAAYTCNCARYTNGARGTNGAR YTNMGNAARGARYTNGARAGYCAYMGNCARACNYTNYTNACNCARYTNGCNGCNGTNAGY GAYGTNTCNCARGCNGAYYTNCARCAYGCNGTNAAYGCNGCNACNATGGGNCAYACNGAY AGYAARGCNGCNAARMGNYTNGCNAARGAYYTNAARGARAAYGTNGARMGNGCNAARTCN TCNATG------TCNTAYGGNGAY---MGNGAYGAYGAYYTNGGNTAYMGNMGNAGYAAY ACNGAYATGGAYAAYMGNCARGCNCAYCCN------AARACNMGNAARGGNTCNGCNGTN TCNAAYCARMGNMGNGCNAGYGCNMGNACNGCNTTYGTNGAYGARGAYGARGARGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARAARGAR GCNTGYGAYATGTTYAARATGATHCARYTNTAYATGGGNGAYMGNAARGGNAARAARTTY CAY--------------------------------------------------------- ---GGNTCNCARAARYTNCARACNYTNGCNAGYGCNYTNTCNCCNTGYTAYYTNMGNYTN MGNGGNACNTAYGCNGAYTTYYTNACNTTYGAYCCNGAYGGNAAR------GARTCNYTN TCNGCNGTNCARAARCARGGNCARATHAAYGARACNATGACNGGNTTYGGNYTNYTNGAY CAYYTNGAYAGYCARGTNCAYAARAAYATHGAYAAYTTYACNATGACNGGNGARYTNTGG GGNCARACNATGAARTTYACNAAYYTNGTNGGNTGGGAYGTNATGTTYGAYTTYAAYYTN TTYAARMGNAGYAAYGGNTCNTGGGAYCCNACNAAYGCNGARCARYTNYTNAARTAYTCN GCNYTNMGNGGNTAYAAYATHCAYGCNTTYCARYTNGGNAAYGARCCNAAYTCNTTYMGN CAYAAYTTYAAYTTYAGYATHTCNGCNGCNACNYTNGTNAARGAYTTYGAYATHYTNMGN AAYATHYTNTTYGARTAYCCNCARTAYATGAGYAAYAAYYTNTAYGGNCCNGAYGTNACN AAYYTNAAYMGNCAYTCNTCNTCNMGNAAYTAYYTNCARGAYTTYGTNAGYGCNGGNGGN GAYMGNGTNGTNAAYGARATHTCNYTNCAYCAYTAYTAYYTNAAYGGNMGNACNGCNAAR GTNAAYGAYTTYTAYGAYATHTCNGTNYTNGAYTCNYTNAARYTNGARTTYGARGARGGN CAYAARYTNGCNGGNGGNAGYCCNATHMGNYTNACNGARACNTCNTCNTGYTAYGGNGGN GGNGCNCCNGGNYTNTCNGAYMGNTAYGTNGCNGGNTTYYTNTGGYTNGAYAARYTNGGN YTNGCNGCNAARCAYGGNGTNACNAARGTNTTYMGNCARACNTTYTTYGGNGGNAGYTAY TCNYTNGTNTCNAARAAYATGGAYCCNAAYCCNGAYTAYTTYYTNTCNYTNYTNCAYAAR MGNYTNATHGARGGNCCNGTNTTYAAYGCNACNGTNCARCCNAGYATGAARTAYYTNMGN ATHTAYGCNCAYTGY---ACNMGNAAYTCNGGNCARTAYATGAARGGNGCNATHACNYTN GCNATHYTNAAYACNAARAAYGARTCNGCNACNGTNAGYYTNGGNCARTTYCCNGCNTCN CAYGTNGAYYTNTAYATHYTNACNCCNGGNGAYTCNYTNGGNYTNAARTCNMGNTAYGTN AARYTNAAYGGNGARATHYTNATGATGTCNGGNTCNTCNYTNCCNCCNYTNAARCCNAAR GCNCAYAARGGNGAYGTNGCNTTYCCNGCNYTNTCNTTYGGNTTYATHGTNGTNCCNGAY GCNAARGTNCCNYTNTGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GTNMGNYTNTAYTAYCAYGGNYTNCCNAARCCNGTNTGGYTNGAYGGN CARTAYCAYGARATGMGNATHGAYGCNCCNCCNMGNAAYGTNYTNATHGAYGGNGGNCAR MGNGGNTTYCARATHGAYGGNMGNGAYATGATGYTNYTNGTNGAYMGNATGGARAARGGN CCNTAYGGNGGNCCNCCNMGNAARATHYTNATHGGNGGNGCNGARCAYGAYATHAGYTTY CARTTYCCNCCNMGNMGNATHYTNATHGAYGGNAARCCNTGYGARYTNAARYTNGAYAGY AARATHCCNTTYGTNATHATHGARGGNAARCCNCAYGGNATHMGNTTYGAYGGNGARCCN MGNACNYTNTTYATHAAYGAYCARCCNTTYACNATHCCNYTNGAYMGNGCNGARAARATH MGNATHGGNGCNMGNCCNACNTAYGTNGCNTTYGGNGGNCCNGCNCAYGARATHATHATH GAYGGNAARTGGTTYGARGTNAARTTYGAYAAYACNYTNAARGAYATHCAYYTNGGNAAY MGNCAYTTYCARATHMGNATHCCNGGNCCNYTNCCNMGNGTNAARATHYTNGAYCARYTN YTNATGAAYTTYGAYGTNTCNMGNYTNATGGTNGCNAAYACNGCNGARGTNCARMGNATG CCNACNTCNGGNYTNCARCARCCNGTNAAYATHCARCCNCAYMGNCCNGGNCARATG--- ---------------CCNACNATGAAYGTNGGNCARAAYCCN------------------ ---------------ATGGTNCCN------------------MGNCCNATHAAYTCNAAY CARGTNGARATGCAR---------------------------------GGNCARGTNCAR CCNCCNYTNTCNGAYATHAAYCCNATG--------------------------------- ---CARACNGCNCCNAAYCARGCNCARGTNGCNATGCARATG------------CARAAY CAYYTNCCNCARGGNATHCCNAAYATH---------CCNCCNMGNCCNAGYATGATGCAR CARCCNGCNAGYTTYATHMGNCCNGGNATGATGGGNCCNCARATHCARGGNAAYCCNGTN ATHCARCCNATGGGNATGMGNMGNCCN------------------------------YTN CCNAAYYTNATGGCNYTNCARCARAAYCCNCARATGATGTCNAAYGTNATHGCNCARGGN YTNYTNAAYCARGTNGCNAAYAGYATGYTNMGNCCNCARGTNCCNGGNATHCCNAAYATH GCNGCNTCNATHMGNGCNYTNACNGCNCARACNMGNGTNMGNCCNCARCAYAAYYTN--- ---GGNGAYATGCARTCNGCNGTNATGGCNACNGGNATGCARGGNTCNGTNATGAAY--- ---CARAAYAAYATGGCNCCNGGNATGATGTCNTCNGCNAGYAAYTCNGGNATGTCNTCN AAYATGGGNCCNATHAARYTNGARCCNAARCCNCARATHTCNATHCAYGGNATGTCNYTN CCNGGNATHYTNTCNTCNGCNACNTCNCARAGYACNTCNAGYATHTCNACNACNAGYTCN GAYTCNTCNAARCCNTCNGCNGGNYTNGAYATHAAYTCNYTNYTNAGYAAYYTNATHAAR GTNGGNYTNATHAAR---------------GARCARAARCCN------------------ ---------------GAYGTNGCNCCNTCNGCNTCNGARTCNAAYTCNGARGAYAARAAR CCNACNCCNYTNTCNAARAAYGAYAAYATGCCNGAYTTYACNGARTTYGAYCCNGTNGCN YTNAARGTNCCNTAYAARMGNATHGTNGAYGARYTNCAYGARGGNATHCARTGYCAYACN TGYTCNGCNMGNTTYACNGCNGARGAYCARGARAARTAYMGNGCNCAYYTNGAYTGGCAY TTYMGNCARAAYAARYTNGARCARGARATGGTNAARGTNGCNAARAAYMGNAARTGGTTY TAYACNATHGCNGAYTGGATHCARTAYGARGARYTNGARGAYYTNGARGARAARTCNMGN AGYGARATHTTYGARCARATGMGNTCNGGNACNGARCCNTCNGGNACNGGNGCNYTNGGN ATGGAYCCNTTYMGNYTNMGNGCNYTNGARGGNAARGARTTYATHAARAAYCCNGTNGCN TCNGGNGTNGARGGNGARGAYGTNTGYGCNACNTGYGGNGAYCCNTTYGAYCARATGTGG AAYGARGARACNGARGARTGGATHYTNAARAAYACNATHAARGTNAAYGGNAARACNTAY CAYCCNATHTGYTTYGARGAYYTNCARGARACNCCNACNCCNGTNACNGARACNACNAAY AAYCCNYTNGAYCAYGARATHTCNTCNCAYATGGARGARTCNGGNTCNAAYCARCCNTCN ACNGCNGARCCNGAYATGGAYGTNATHAARCAYAAYATHYTNCARATHATHAARACNGAR CCNCARGARAGYGTNGAYGAYGCNAAYGTNAARATHAARATGGARGTNGAYGARCCNGAR TCNMGNCARGARGCNACNTCNGAYAARTAYGAYACNATGCCNYTNAARACNGARGTNTCN ACNGAYCARTCNGARATHTCNTCNCAYAGYATGGAYACNTCNGGNAARGGNGARTAYTCN GARTCNGARACNCCNACNTAYATHTCNGCNYTNAGYAAYCCNGGNGCNACNMGNAARGTN ATHTCNGTNTGYCARGARGAYCCNAAYTCNCCNTGGGARATGGAYTCNAAYCCNACNCCN GARYTNTCNMGNACNCCNAGYCCNATHCCN------------------------------ ---------TAYGTNTGYTCNATHTGYAAYAARACNTTYMGNATHAARGGNAAYYTNAAR ATGCAYATGTCNGTNCAYACNGGNGARAARCCNCAYAARTGYYTNYTNTGYGARAARGAR TTYACNMGNAARAGYTCNYTNAARACNCAYATHMGNATHCAYACNGGNGARAARCCNTAY AGYTGYYTNYTNTGYGARAARACNTTYGCNAARAAYGAYCARYTNAARACNCAYYTNAAR ATGCAYTCNACNGARAARAAYTAYGTNTGYTCNGTNTGYGGNAARGCNTTYGGNCARAAR CARACNYTNACNMGNCAYATHYTNATHCAYACNGGNGARAARCCNTAYAARTGYYTNTAY TGYAARAARGARTTYAAYACNCARAGYAGYYTNAAYMGNCAYAAYMGNATHCAYTCNGGN GAYMGNCCNTAYAARTGYTCNGTNTGYGAYAARGAYTTY--------------------- ------------------------------------------------------------ ------------------------------------------TGGGAYGARGAYGARGAY GAYGTNGAYGARTTYACNGARGARGARYTNGCNAAYGAYCCNTCNAARMGNATHYTNTGG GCNTCNGARAAYAAYAARGTNGAYATHGTNGARGARYTNYTNAGYAAYAAYCCNGARYTN GTNTCNGTNTGYGAYAGYGAYTGYTAYACNCCNYTNCAYMGNTCNTCNTAYAAYAAYCAY CCNGAYGTNGCNAARYTNYTNATHTCNCAYAARGCNAGYGTNCAYGCNAARACNGTNGAY GGNTGGCARCCNYTNCAYAGYGCNGCNMGNTGGAAYTCNGTNGARACNGCNCARYTNYTN ATHCAYTGYGGNGCNGAYGTNAAYGCNCARACNAAYGGNGGNYTNACNCCNYTNCAYATG GCNGCNTCNGARMGNGARAAYGGNCARATGYTNGARYTNYTNYTNCAYAAYCCNTTYATH GAYACNAGYYTNGTNTCNMGNGCNGGNGARACNGCNAARCARATHTGYCARMGNTGYAAY TCNCAYTAYCCNYTNTTYGARYTNATHGAYAAYAGYATHAAYCAYYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNATHACNYTNGAYTCN YTNYTNATHYTNYTNCARAGYCARGGNCARTCNGAYGTNCAYCAYAAYTCNCAYATHAAR CARATHYTNGARYTNATHYTNACNGAYGARAARMGNMGNTAYATHTTYGARGARGCNGTN AAYYTNYTNTGYGARATHTAYATHTCNYTNYTNAARGARAARAARACNTGGAGYTCNCAR GTNAAYCARAARGGNCAYATGAARTTYTCNYTNYTNCARGGNAGYGGNCAYTTYGGNGTN MGNTTYGGNTGGYTNGAYGARYTNCCNCCNTTYYTNGGNACNGARCARATGYTNMGNCCN TGYCARAAYYTNGARGTNAARMGNATGTTYGGNCARGGNTCNMGNGTNGGNTCNAARCCN ATHTCNGCNACNCCNGGNCARGARGAYAARTTYGARTGYCCNTGYTGYYTNTGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNCARTGGAARMGNTAYATGATHAGYATHCARGCNTCNGCNYTNACNGTN TGGATHCARAGYGAYAGYAAYGAYTGGAAYCCNGARYTNGAYTGGMGNYTNCCNTCNGAR GTNCAYGTNTTYCAYGCNTGYATHYTNCCNGTNAAYGAYAARATHGCNATHGCNGCNAGY GGNTGGGAYAARAAYCARGCNTTYGTNTCNGTNTTYGTNTAYGAYTTYTCNAAYGAYGAY ACNTTYMGNTTYAAYATHCCNGAYYTNGARAARTGYCCNTCNYTNCARYTNYTNYTNGGN ATHTCNAGYGAYACNCAYCAYACNGTNMGNAARATHATGTTYCARAAYTCNTTYCARGAY GTNGCNACNAAYGARGCNTTYGAYACNYTNCARGGNAARYTNAAYACNYTNGCNYTNTGY GGNGGNYTNGARAAYGCNTGYGTNAGYYTNACNTGGGAYCARMGNATHACNATHTGGAAY ATHGCNTGYMGNGTNGCNYTNAARACNGTNACNYTNCCNGAYGAYTTYCCNTGYYTNACN GCNATHATHGCNGTNAARGCNGTNAARGGNYTNYTNYTNYTNTCNGCNTCNTGGMGNATH GARGAYACNGGNGAYTGYGGNGGNATGATHATHYTNAAYCCNACNACNGGNYTNGTNTAY AARACNACNGTNTGYAAYATHCCNAAYGCNGGNTGGMGNAGYTCNGARAARGTNAARGAR GARAGYAAYCAYGTNTTYGCNGTNAGYAGYTCNGGNTCNGTNTCNTGGTGGAAYGGNAAR AGYGGNAGYYTNGTNGGNTAYMGNCARTCNAAYATHGCNACNTGYGTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATH TAYGTNMGNGCNGCNTAYYTNMGNAAYTTYGARATGAAYCCNTTYCAYCCNGGNACNAAR GTNAARACNYTNATGGARTCNTGYATGACNTCNGTNYTNCARAAYYTNGAYATGTTYGAY YTNGARGARTTYCARGAYGARTAYACNATHAARMGNATGATHCAYMGNYTNAARMGNACN AARACNATHACNAAYAARGCNYTNGCNGTNYTNYTNGTNCCNACNYTNACNMGNYTNGAY ATGGARGGNATHTTYYTNACNAAYAAYACNYTNMGNYTNYTNTGGACNCARTGYCCNAAY YTNACNGGNYTNAGYYTNAARAAYTGYGGNTAYATHGTNACNGAYACNGTNYTNACNCAR ATHGCNAARAAYYTNCCNAAYYTNGARCARYTNAAYYTNTGYMGNTGYAAYCAYYTNACN GARAARTGYYTNGCNATHYTNTCNAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CARGGNCARCCNGCNCCNGGNTAYCCN---CCNCCNCAY CAYGGNCARCCNGGNGGNTCNCARGARGARGTNTCNTCNATHGARCARTCNCCNGAYCAR AAYACNCAYCCNTCNGTNGCNGCNATHGGNACNMGNCCNATHTCNGGNTCNCARAAYTCN ACNCCNCCNYTNAGYMGNAARTCNCCNACNTCNGAYCARGGNGTNCARGTNCARCCNMGN AGYCCNGARAARTCNAGYAAYGARAGYCARCARCAYCAYCARCAYCARCAYCARCAYCAY CARCAYCAYCAYCAYCCNMGNGGNCARGGNATGMGNCAY--------------------- ---GGNGGNCARCAYMGNGTNGAYAAYMGNAAYGAYGGNMGNGTNAAYGARCCNMGNGGN GAYMGNAAYGTNACNTCNTCNTTYGTNMGNGGNMGNAGYAGYAAYMGNGGNCARCARATG MGNGARGGN------GGNACNATHMGNGGNCAYGGNCAYCCNMGNCAYMGNGGNMGNGGN GGNMGNTCNGCNGARCCNYTNAARTTYGAYACNGAYTTYGAYTTYGARACNTCNAAYGCN CARTTYGAYAARGAYCAYATHGARAARGARYTNAARAAYYTNTCNYTNAGYGAYAARTCN YTNAAYGGNGAYAARACNGAYGAYGAYCCNGARATHGARGARGARGARGGNGARGARGAR GARGAYGARACNGTNTAYTAYGAYAARAARAARTCNTTYTTYGAYAAYATHAGYTGYGAR GCNACNGARAARGCNMGNGGNCARMGNGTNACNTGGMGNGARGARMGNAARYTNAAYAGY GARACNTTYGGNATHTCNGARAAYTAYMGNMGNAAYTAYMGNGGNMGNGGNAAYTGGMGN GGNGGNCAYCARMGNGGNGGNTGGMGNGGNMGNGGNMGNGGNGGNTTYAAYAAYMGNGAR GGNGGNTAYTAYGGNAAYMGNGGNGGNGGNMGNGGNGGNMGNMGNCAYCAYGAYTGGGGN GAYMGNMGNMGNATGGAYGGNCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNTTY GARATHTGYAARTAYTCNMGNAAYYTNGARGTNYTNTCNGTNYTNTAYAAYMGNAAYATH ACNCAYGCNGGNATHTTYGCNATHTTYMGNTCNYTNGAYGTNACNYTNAARMGNYTNAAR TCNTTYAGYTTYGTNTAYAAYGCNTTYYTNAAYYTNYTNYTNAAYATHGGNTCNGGNAAY GTNGAYATHYTNTTYGTNGAYGCNCAYCCNCARGGNAGYYTNGAYGTNGTNTGGTCNACN YTNTTYGGNAARGTNCAYMGNGCNGGNATGYTNGARCAYCCNACNYTNGTNGARAAYYTN GTNTGGGGNTAYCCNAGYTAYTCNAGYCCNYTNATHGAYTGYTAYMGNAARGCNGTNCCN TAYYTNGARGARTTYMGNGAYTTYGTNYTNTCNMGNCAYGARGTNGAYGCNTCNCAYGTN ATHGAYTGYAAYCAYYTNAAYGTNGTNATHGTNTGGMGNCAYAAYTAYACNGCNCAYCCN MGNAAYAGYCARGGNAARGTNGTNMGNMGNTTYTCNAAYGARGARGARATHYTNMGNGCN GCNCARGAYGCNTTYGGNCCNTCNGCNGTNGTNACNGGNGTNCARYTNGAYACNATGACN ATGAARGARCARYTNTCNYTNATHTCNTCNTGYGAYTAYCCNACNGARGTNGARGTNTCN CAYGARGARTTYAARTAYGTNGARCARGTNYTNCCNCCNACNACNGTNCCNAARATHCCN CARCAYTCNTCNTAYCCNACNCCNTCNGGNTGGGTNCCNCCNAAYGAYGAYATHMGNTCN CARCARCCNTAYYTNGTNMGNMGNACNAARAAYCAYGTNYTNCCNATHTAYCCNGARCAR AARGARGTNTGGGGNMGNATGATGCAYCAYGTNACNATHMGNAAYATHGARGGNGAYATH TGGAARYTNGARTCNGARYTNMGNCAYCAYYTNAARCARAAYATGGCNGARGARGCNGTN ATHTCNCARGTNCAYGARGTNAGYMGNTGYATHMGNATHMGNGGNCARCAYMGNGCNACN ATHGCNGARTTYYTNYTNGARAARGGNATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AARAAR MGNMGNMGNACNTTYGARYTNGARGARCCNACNYTNAARGGNGAYAGYACNCCNACNATH GARAAYGARCARGCNMGN---ACNACNMGNYTNCARACNTCNMGNAAYGCNACNCCNCAR GAYGARCARAGYCARCCNYTNAARMGNCARMGNMGNAGYACNTAYGAYAARAARACNCCN GAYYTNAARGAYGAYAARTCNTCNGCNTCNCARCAR---------------AGYAGYCCN AGYGCNMGNGCNATHYTNGAYTCNATHCARGGNGAYTGYTCNAGYGCNGARMGNMGNGAR AARATHYTNTCNGCNATHGAYAARAARGTNCAYYTNAARATGGTNTCNAGYCCNTCNAAY CCNYTNAARAGYCARCCNAGYCARATHCCNMGNTTYATGACNTAYYTNACNAAYAARAAR AARGARAGYCARAAYTCNGCNACNCCNMGNAGYAARAAYTGGAAYAARATHCAYAARAAR GARTTYTCNAARTTYGAYTCNATHGAYGTNTAYYTNGAYMGNAARCAYCARMGNAARGAR AAYYTNTCNAAYAGYACNAARAARCAYYTNGCNAARAARTCNCCNGCNGTNAAR---TCN TCNGCNMGNATHGCNAARCCNGTNCARAARGCNCCNGAYTCNTCNAARATHTTYAARCCN ACNGTNGTNTCNACNAARAAYATHAAYTTYGAYTTYACNAARATG---ACNTCNGAYTCN TGYAARACNCCNTCNACNTCNAGYAARACNCCNMGNTCNMGNACNGTNGGNACNCCNAGY MGN------AARGAYATHCCNACNTCNACNAARYTNAARGAYGTNGGNTCNACNACNGGN GCNACNCCNTTYAARTTYACNGGNACNACN---------AGYTCNYTNAAYTCNACNTTY ACNTCNTCNAARAARGGNGGNTTYGAYYTNAARGCNAGYYTNTCNMGNCCNYTNACNTGG AARCCNCAYACNGGNAARYTNCARCCNATHGAYGTNAAYGCNGCNAARGCNCCNATHYTN AARGCNGCNAAYGTNACNATHAGYAGYAARGCNMGNGAYGTNATGMGNMGNGAYTCNGCN AGYMGNAARMGNCCNATHCARGCNAARAAYGTNMGNMGNGCNGCNCAYYTNGAYMGNMGN AAYAAYCARAARTAYGTNGAYATGATGAARMGNMGNGGNYTNATGGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CAYCARGTNACNCARGARGARGAYGGNACN ATHTTYATHGAYMGNGAYGGNACNCAYTTYMGNTAYATHYTNAAYTAYYTNMGNGAYGGN GGNGTNAAYCARGAYAGYYTNCCNMGNGAYMGNCARGTNYTNAARGARYTNATGCAYTTY GGNTCNAARTAYGTNTAYYTNGGNAAYGAYAARGARGAYGARGARGARGTNAARGTNTCN GARGCN---GAYATHGTNYTNTCNGAYAGYGAYGTNAGYGAYGAYGAYGGNGARACNTGY YTNYTNGAYATHYTNGAYACNGCNGGNCARGARGARTAYTCNTCNYTNAARGAYCARTAY GTNMGNACNGGNGAYGGNTTYGTNATHATHTAYAGYATHATHGAYCARGARAGYTTYAAR GARGCNGARGCNATHTTYMGNTGGYTNAARMGNYTNAAR---GARGAYAAYTAYCAYGCN ATHYTNGTNGCNAAYAARCARGAYYTN------AARGAYGARGCNACNGTNAGYACNCAR GAYGGNCARGAYYTNGCNGCNMGNYTNGGNATHCCNTTYTTYGARACNTCNGCNAARGAY GGNTCNGGNGTNGTNAAYGCNATGAARGGNYTNATHMGNATHATHCCNMGNACNGGNAAY GAYTAYAARATHGTNATGYTNGGNAGYGGNGCNGTNGGNAARTCNAGYGTNACNATHMGN TTYGTNAAYGGNAAYTTYGTNGAYGAYTAYGAYCCNACNATHGARGAYTCNTAYMGNAAR ATGATHAAYGTNGAYGGNYTNTCNGCNGTNACNAARGAYACNMGNAARGCNGCNAARNNN NNNAARNNNAARAARAARMGNGCNGGNATHAGYGGNGAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNAGYACNATHAGYMGNCCNTCNAGYGCNATHTCNACNACN ACNGGNMGNGARCCNTGGGARGAYGAYACNTCNATHATHACNAARAARATHYTNAARTCN CARGCNMGNGCNCARATGGGNAARMGNGARTCNGTNTAYCARTCNGCNGGNGCNGTNATG ACNTCNCARTCNTCNAARAARGTNMGNGAYYTNGCNMGNAARATHMGNATHACNTCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARACNAGYGGNCARAGY CARATHTTYAARGAYTTYCCNMGNAARMGNTCNYTNGTNGAYATGCCNGTNGTNACNACN YTNTTYTAYTGYTGYYTNTAYCAYTTYGAYYTNTCNGARAAYTCNYTNGGNAGYCCNGCN GCNATHMGNAARMGNCAYYTNATGTCNGARAARCARTAYGTNTGGACNGCNATHGGNGCN MGNGCNAARGTNMGNCAYTGGAARGAYATHGARACNATHYTNACNACNAARGGNTGGTTY GGNGGNTCNAARYTNAARTCNGTNATHGGNTTYGAYAARATHGTNGGNATHYTNCAYMGN AAYAAYGCNCCNYTNGAYGTNYTNGAYAARTAYYTNGCNYTNATHGAYGAYACNGGNGTN MGNYTNGCNYTNGCNACNAARGTNAARTGYCAYAARGCNATHATHGAYACNTAYGCNTCN YTNAARGAYMGNTCNGCNYTNGARACNTAYGCNTCNAARYTNGAYMGNTAYTCNAARGAR GGNYTNTAYGCNTAYGAYGTNYTNAAYGGNTCNYTNGTNAARTGGAAR---------GCN GCNGGNYTNACNACNATHATHAARGARGCNAARCCNATGACNGCNGTNGARCCNTCNCCN ATHACNCCNGCNCCN---GTNGTNGARAARCARMGNGCNATHGTNAARCCNCARATHATH ACNCAYATHATHGARGGNTAYGTNATHCARGARGGNYTNGARCCNTTYCCNGTNCARCAR ACNTCNYTNYTNCARGARTTYATHTGYCCNGARAARACNCARGGNACNGARAARGARTCN GARGARGARGGNACNAGYTAYGAYGARGARCCNCCNACNYTNYTNCCNCARATGGAYGCN CAYYTNYTNTCNAGYCCNACNYTNAAYGAYYTNGGNGARGARCCNAARGARAAYCCNCCN ---------------------------YTNAARTGYGARATHTGYCARAARGTNGCNCCN GCNTCNACNTTYAAYAAYTCNGGNMGNTTYTGYTCNYTNTCNTGYTCNMGNMGNCAYAAY GTNAGYCAYACNMGNMGNGTNGGNYTNTTYAARCCNAARGGNACNTCNMGNAARMGNAAR CARATGYTNGTNGGNMGNAARGGNTGGMGNACNTCNMGNGGNGGNMGNYTNCCNTAY--- ---CCNAARAAYCARTGYATGGAYGARAAYTCNCARAAYACNAAYGARAAYCCNGTNGGN GAYGARATGAGYAGYTCNAAYAGYACNCARGAYACNAGYTCNTCNGCNGCNTCNCCNCAY TCNGCNYTNGAYTTYAAYATGGAYGTNGAYGCN---AGYATHCCNACNACNGAYCCNTCN AARTGGACNGTNACNGARGTNTAYGAYTTYGTNYTNGCNYTNCCNGGNTGYTCNGAYTAY GCNGAYGAYTTYMGNTCNCARGARATHGAYGGNCARGCNYTNYTNYTNYTNAARGARGAY CAYYTNATGACNGCNATGAAYATHAARYTNGGNCCNGCNYTNAARATHTGYGCNAARATH AAYTCNYTNMGNATHGAY---CCNCCNTTYCAYACNAGYTGYYTNTCNAAYGTNGAYCAY MGNAARGARMGNGCNGTNATHAARCAYYTNTAYTAYMGNGAYCAYGARAARACNYTNAAR CARACNTAYAGYCCNGTNGTNGARYTNCCNGAYTAYACNTAYYTNGAYGGNMGNCCNACN GARATGACNYTNTCNTAYAARGARAARCARGARAARAAYTAYAAYYTNGCNAARCARGTN GTNAARYTNGTNGAYGARGTNAARTTYGCNCARAGYCARTTYGCNACNAAYGARAARGCN AARGARAARCAYGARCAYAAYMGNAARAARCARCARYTNAARGARAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGTCNATGGARYTNGTNTCNAARAGYYTNGARATGGARGAYATGGGNAARAARGGNGAY ACNYTNAARGGNCAYAAYAARAARAARAARYTNAARACNAAYGAYGCNATGCARGTNATH AARACNGAYMGNCAYGGNGTNTGGMGNGARYTNMGNAARGTNMGNAARAARCARYTNAAR GARATGACNAARAARAARAARAARGARGTNTTYAARTCNGCNATHGARYTNTAYAARGAY GARCAYGAYGTNGAYTAYACNGAYAGYAAYGTNGARACNYTNYTNAARATHTCNAARYTN GGNAARGTNAARCCNAAYGAYGCNCARAARATHYTNTAYCARCARCCNTGYMGNYTNTCN AARTAYGTNAARGARAARGTNGARGCNGARGCNCCNGCNTCNATHTTYACNGAYCARGAY TTYGARAAYTTYGCNAARGARTAYAARCCN------------------------------ ------------------------CCNATHGGNGGNGGNAAYCARCARGAYMGNCARAAY MGNAARYTNYTNYTNGARCAYATHGARGARCARAARAARMGNYTNCARCAYGGNCAYCAY TCNTCNTCNAGYAGYCCN---ACNCCNTCNATGAGYGCNAGYCCNGCNACNATGYTNAAY AGY---CCNTCNTCNGTNCCNGGNYTNACNGCNGCNGARTAYGCNACNATHAGYAAYCCN CARCARMGNGCNGCNYTNCARCAYGCNCAYGCNAAYTCNGTNGGNTTYTTYATHACNCAR GAYTCNTCNTTYGGNAAYYTNATHYTNCCNGTNYTNCCNMGNGCNCCNGAYGTNAARGTN GARTCNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARCARMGNCARTTYYTNTAYYTNGCNCAYACNGCNYTNGGNACNCAYCCNYTN AGYGAYAAYGTNACNAARGCNATHTCNGARYTNCARACNTCNGTNCCNGAYYTNACNGAY TAYTAYCCNGCNTAYYTNTCNCARGARTTYACNTGYAARGAYGGNAAYATHATHMGNTTY GCNAARGAYGGNTCNYTNTCNMGNYTNTAYGAYTCNGCNAAYCARGTNGARTGGGCNTCN CCNGAYCAYCCNATHGGNCARYTNATGTAYAAYACNTAYGTNGARCARGAYTTYACNGAY ATGGCNAARYTNTAYAAYTTYGAYGCNGGNGTNGGNTAYGAYAARCCNAAYGTNACNGCN AAYGCNCAYCCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN GCNCARGARAAYMGNGARMGNCARYTNGARATGMGNMGNCARAARATHGARGAYYTNMGN MGNMGNGAYACNGARMGNMGNGCNGCNGTNGARGARMGNMGNMGNATGAARGARGARATH GARMGNYTNMGNAARGARTCNATHYTNCARAARGCNGARGARMGNGTNGCNMGNTAYGAR GCNTGGMGNGCNGGNGGNMGNAARGGNGGNYTNGGNTTYGGNAGYTCNGCNCCNMGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GAYGTNGTNATGATG ATGGARYTNCCNAAYGGNGCNAGYYTNACNACNAARAARGAYYTNTAYYTNCARGCNGCN GGNYTNTGGTCNGAYCARCCNGTNGTNAARYTNGAYAAYATGYTNTAYGTNGGNAARGTN TCNCARACNYTNGGNTCNCAYYTNTTYATHGAR--------------------------- ------------------------------------------------------------ ---------------GTNAAYTCNAAYGGNCARGTNYTNGARTCNCARTCNCCNTGGMGN TTYTCNTTYATHCCNGARGCNATHTGGGGNATHATHAAYTTYATHGTNYTNTTYTTYCAR ACNATGTTYAAYCCNAAYAARAAYAGYAARGGNGAYAAYTAYACNTCNGAYTAYMGNMGN CCNGGNGGNGGNGGNCCNCCNACNMGNMGNATGGGNGGNTTY------MGNMGNGGNGGN GGN--------------------------------------------------------- ------------------------------------------------------------ ---------------------GTNMGNGTNGTNGARAARGCNACNGGNYTNGAYCARTTY ATHMGNAGYTGYTCNAAYTCNAARGARAARGGNTGYTTYGAYAGYAGYCCNGGNTAYMGN ACNTGYGCNGARGTNTGYAAYACNGAYGGNTGYAAYTCNGCNTCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TGGTCNMGNGAYGGNGGNGGNTGGGTNCARTTYGTNGCNGCNTCNGCNATG YTNACNACNGCNATHYTNTTYYTNTTYCAYTTYTTYAAYYTNYTNCCNMGNYTNCCNGGN CCNTGGACNTTYATHGARTTYYTNTAYTAYTGYGTNTAYTGYATHYTNTTYGTNATHGCN GCNATHGTNTGYGCNGTNMGNGCNCAYYTNACNGCNGCNATHGGNGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARCARYTNGARAARCARCARMGNGARACNGGNYTNAAYACNAGYATHTCN GARACNAGYAARGGNTTYGCNYTNYTNCARAARATGGGNTAYAARCCNGGNACNGGNATH GGNAARTCNGGNGAYGGNMGNGTNGARCCNGTNTCNTTYGARGTNAARACNGGNMGNTCN GGNYTNGGNAARGAYACNGAYATGAARMGNAARTCNTCNGARATGAAYAGYATGMGNGCN GCNATGGTNGCNAARMGNAARAARGTNCAYCARAARCARACNGARTCNTTYCARAGYMGN YTNMGNGAYAARTTYAGYGAYMGNYTNYTNGARAARGAYYTNMGNACNGCNCARAARGCN TGYATGCARYTNGAYCARCARGCNGGNYTNYTNGARCCNYTNGARYTNTTYTTYTGGCCN GCNAAYGGNYTNCCNAGYGTNCARTCNGARGARGTNTAYGAYGAYAARGAYACN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GTNCAYCARGGNGAYGTNGCNACNYTNCCNTGYACNGTNCARAAYYTN GGNGCNMGNCARATHTCNTGGAARAARGTNGGNAAYGARCAYTTYYTNAGYATHGGNACN GARATHTGGGTNCARGAYCCNAAYYTNATGATHCARCAYCAYACNTGGCCNGCNGARGTN AGYAAYTGGAAYYTNGARTTYMGNTCNGCNMGNYTNGARGAYAGYGGNGTNTAYGARTGY CARATHATHTCNACNGARAARATGACNYTNACNGTNGARYTNTCNGTNATHGARGAYATH ACNMGNTTYTCNTGYGAYGTNATHGTNAAYGCNGCNAAYAGYMGNYTN------GGNGGN GTNGCNMGNGCNATHGCNGARGGNGCNAARYTNACNGAYGARTGYGARAARTTYACNTCN CARAAYACNMGNATHGARGTNTCNCAYCAYTTYGCNTCNTGYGGNGGNAAYYTNCARGTN AARCARGTNTAYCAYGCNGTNGGNCCNAARTGGGARAGYTAYAGYACNAGYCCNGAYGAR TGYAARMGNGTNYTNMGNYTNACNATHYTNMGNTGYYTNYTNMGNGCNGARCARCARGGN CAYMGNTCNATHGCNTTYCCNTCNATHAGYGCNGCNATHTTYAARGTNCCNCARGAYATH TGYGTNGARAGYTAYATGAARGCNGTNCARCAYTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR ACNGTNCCNATHACNGGNCCNATHYTNYTNACNGTNGGNGCNYTNTTYYTNATHYTNGCN TCNMGNCARTTYTTYYTNGCNCAYAARMGNAARAAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ACNYTNGGNGCNGCNGARGCNAARTGGAAYGAYYTNACNGARYTNYTNGTN CARCARGTNTCNYTNGARGCNYTNTCNGARATHGAYGGNATGYTNAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGAYCAYCARTAYGGNATHGCNGTN ACNAAYAARTTYGCNYTNTTYATHGAYGARGCNGARGAYCCNTTYGARGCNATHTCN--- ---------------AARAAYAARAGYAARAARGAYGCNGARAARAARGCNAARGCNAAR CARAARAARAAYACNCCNGTNGCNGARGARAARCCNGCNGCNCCNGARAAYGARGGNGCN AARMGNAAR---------GARGAYAARTCNGCNTCNAARCARACNGARMGNGGNAARGGN AGYGCNMGNAAYMGNGARCCNMGNGARYTNMGNGARAAYGAYGGNGAYMGNMGNCCNCCN MGNMGNCARGGN------------------------------------------------ ------CCNMGNGARAAYAARGAYGGNAARGTNGGNGAYGARAAYGTNCCNCCNGARTTY MGNGARMGNCCN---GARGGNGGNTTYAARMGNMGNGARGAYMGN------GARGCNGGN GGNTTYGGNGGNGARMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNGGNMGNGGN GGNGAYMGNGGNGGNAGYGGNGGNTTYGGNCCNMGN------------------GGNGAY MGNAARMGNGARTTYGAYMGNCAYAGYGGNACNGAYMGNACNGGNATHAARCCNATHGAR AARAARGARGGNGGNGGNGCNCAYAAYTGGGGNAGYTTYMGNGAYGAYATHGARGARCAR GGNCARGTNAAYGCNACNGARACNTCNGGNGAYTGGGGNAAYCARCAR------------ GARAARCCNGARYTNAAYGARAGYGGNGARGCNGARAAYGCNACNGARGARGARGCNCAR CCNCARCARATGACNYTNGAYGARTGGAARGCNYTNCARACNCARCAR---AARCCNAAR CCNGARTTYAAYACNMGNCARGCNGGNGARGGNGTNGAYTCNGGNCARTGGCARAARGGN ATHGARTAYCARAAR------------------GAYGARGCNAARGAYGGNGARTAYGAY GARGGNGARCAYAGYGAYCAYCAYATHMGNAAYAGYAARCARYTNGTNACNGAYATHMGN ATHACNTTYAAYGAYAAYCCNMGNMGNGGNMGNGGNMGN---MGNGGNGGNMGNGGNGGN ATGGARMGNGGNGGNCCNGGNGGNGGNGGNCCNGGNAGYMGNGGNGGNMGN------GGN AGYTCNMGNGGNTTYGGNGGNAAYAARAARGARGCNGCNCCNMGNTTYGAYGAYGARTCN GAYTTYCCNTCNYTNYTNAARACNGCNGCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AGYGGNAARTCNAGYATHGGNTCNMGNYTN TCNAARACNYTNCCNAAYTGYGTNTGGATHTGYCARGAYCAYTAYTTYYTNTCNGCNGAY GAYCCNMGNGTNGARATHGCNCCNAAYGGNATGMGNAAYTGGGAYACNYTNAGYGCNYTN GAYATGGAYACNATGYTNAGYGAYGTNTTYGCNTGGATHAARAARACNCARGGNCCNTCN CCNCAR------GCNTTYYTNATHGTNGARGGNTTYACNATHTTYAAYCAYMGNCCNYTN GCNAAYYTNTGYGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNCAYGTNMGNTAYAARAAY---AARCARMGNGTNAARGAYGCNAARGTNCAR GTNGAYAARAAYAARAARTTYATHTCNAARAARGAYAARAARAARAARTCNCARYTNTCN GGNAGYGGNYTNGGNGARAARCAYACNATHYTNGCNGARAAYCCNGTNGAYAAYGTNTGG ATHMGNAARTTYTAYCCNMGNCCNMGNTTYTCNATHGARGARGCNATHAAYMGNCAYCAR GCNTTYGCNCARCCNTCNATGYTNGAYAAYGGNGAYGGNYTNGCNTAYYTNGAYATGYTN YTNGAYTTYMGNACNAARAARCARACNAARTTYYTNAARAAYATHMGNTCNACNATHYTN YTNCCNCAYCCNTTYACNTGGGGNGTNCCNCCNTCNATHYTNGTNTTYTGYAARGARGAR GARCAYACNCAYYTNGCNTTYTCNYTNGGNGCNAARCARGCNGGNTCNCCNTCNGARATH ATHAARATGATHGARAAYGGNGTNYTNAAYCCNAARGAYTTYACNCAYGTNYTNGCNACN GCNGAYTGYGCNTCNGAYATHACNCCNGCNMGNTCNTAYTTYMGNGAYAARTTYCCNCAR MGNGCNAARGGNAAYYTNGGNACNGAYYTNAAYGCNATGTGGACNYTNTTYTAYACNGGN TAYACNTAYGARTCNCAYAAYYTNACNGARGCNCARGGNAARYTNCARGTNCCNYTNGGN CARYTNAARCARCCNACNAGYGARYTNGTNGCNAAYTTYGARGCNTTYATHGARTCNATH TGYAARCAYMGNAGYGTNACNYTNGGNCCNTTYATHCARTCNATGAGYGTNGTNGCNCCN CCNTCNCCNGARGAYTTYATHGTNMGNGTNGARGARTAYGTNCCNGGNTAYAARAAYGAR GARYTNGAYTCNGAYGAYGAYGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AAYATHTCNYTNTGYMGNGCNAARYTNGAYATHCCNTTYGGNACNCAYCAY ACNAARATGATGYTNYTNYTNTAYMGNACNGGNYTNMGNGTNGTNGTNCAYACNGCNAAY YTNATHTCNAAYGAYTGGCAYCARAARACNCARGGNATHTGGATHAGYAARATHTTYCCN CCNMGN---GCNAAYCCNTCNGAYCCNGGNGAYTCNCCNACNMGNTTYAARGCNGAYYTN YTNCARTAYYTNTCNGTNTAYMGNTCNCCNCARYTNACNCCNTGGGARAARGCNATHATG GARCAYGAYATGTCNTCNGCNAAYGTNCAYATHGTNGCNTCNGTNCCNGGNMGNCAYGTN ATGAAYAAYAARCAYCAYTGGGGNCAYTTYAARYTNMGNAARATHYTNTCNGARMGNGGN CCNGARCARAGYYTNGTNAARAAYTGGCCNGTNATHGGNCARTTYTCNAGYATHGGNTCN YTNGGNGCNAAYCCNGAYGCNTGGYTNYTNAGYGARTGGGGNCARTCNYTNTCNGGNTGY AARAARTCNATGCCNAGYTCNATHCCNTCNTCNAARYTNAAYYTNATHTTYCCNTCNAAR GAYAAYATHMGNYTNAGYYTNGARGGNTAYAAYGGNGGNGGNTGYGTNCCNTAYAGYATH AARACNGCNTCNAARCARCCNTGGYTNACNCCNTTYYTNAGYCARTGGAARTCNAARGGN MGNGGNMGNTCNGGNGCNGTNCCNCAYATHAARACNTAYACNMGNTGYTCNCCNGAYGGN TCNCARGCNGCNTGGTTYYTNGTNACNAGYGCNAAYYTNTCNAARGCNGCNTGGGGNGCN YTNGARAARAARGGNAGYCARYTNATGATHMGNTCNTAYGARATGGGNGTNYTNTTYYTN CCNCCNGAYTTYGGNTGYAARAAYTCNTTYGGNGTNAGYAGYCAYACNGAYATHGTNATH GAYCCNGGNMGNAARGTNTTYCCNYTNCCNTAYGAYYTNCCNCCNACNACNTAYATHAAR GGN---AARAARTCNGTNGARYTNTTYTAYGAYGTNGTNTCNCCNTAYTCNTGGYTNGCN TTYGARGTNATGTGYMGNTAYCARACNMGNTGGAAYATHAAYYTNAARYTNMGNCCNTTY TTYGTNGCNGGNATHATGCARGGNGCNGGNAAYMGNGGNCCNACNACNGTNCCNAAYAAR GGNMGNCAYYTNTTYYTNGAYATHATGMGNTGYAGYCARTAYTGYGARGTNCCNYTNAAR ATHCCNCARAAYCCNTAYGARYTNATGTTYGARAARGGNTCNYTNAARGCNCARMGNTTY YTNACNGCNYTNGAYATGACNAAYCCNGAYAARGTNGARGCNGTNTCNMGNGARTTYTGG ATGMGNGGNTGGGGNMGNGAYGARGAYYTNACNGAYGAYTCNAGYATHGCNGARGGNGCN AGYAARGCNGGNYTNAGYCARCARGAYATHCARAGYYTNYTNTCNMGNACNAARGAYTCN GAYGTNAARGGNMGNYTNAARGGNGTNACNGAYGARGCNYTNGARYTNGGNGCNTTYGGN TCNCCNATGATHGTNGTNGAYGTNAAYGGNGARAARGARTGGGTNTTYGGNAGYGAYMGN TTYCCNATHYTNGCNCARATGYTNGGNAARATHAAYTAYGGNGTNTGGAARYTNTGYTTY ACNGCNMGNAARCCNGAYGGNGAYTGYAARGCNTGG------GAYGAYAARATHAGYCCN GGN---------------------GAYTGGYTNAARGGNGTNCARGCNATGGGNATHYTN GGNGCNYTNTTYYTNGCNTTYGGNGCNGTNYTNGCNGTNYTNAAYYTNGTNGTNGARAGY MGNGGNGAYMGNGTNMGNYTNTTYCCNTAYTTYATHGCNAGYYTNTGYTTYGTNGGNGGN GTNYTNACNYTNATHGGNGCNATHATHGTNACNGCNAARTAYAARTCNGTNCARAAYYTN CCNAAYCCNACNCCNYTNCCNYTNGCNGTNAARACNYTNATHGGNGAYGARTTYTCNYTN AGYTGGGGNTTYGGNYTNGAYATHYTNACNGTNGTNYTNGCNTGYYTNGCNGGNGGNATG CAYATHYTNGCN------TAYGTNYTNYTNGCNGAYGAYTAYTCNMGNGCNACNCAYATH GCNMGNGTNGCNGTNYTNTCNGTNATHACNYTNAGYGTNTGGTAYMGNGAYGTNATHCAR ATHMGNGTNGAYAGYYTNTGGGCNCAYYTNMGNGARGAYGARYTNTTYCARTCNGCNCAY TAYGARACNATHTAYGTNACNGTNGTNTAYACNATHYTNATGGTNTTYTAYCCNTTYGCN ATGCAYCAYATHCCNTAYYTNCARMGNTTYAARGTNTCNAARGAYGTNAARTAYGTNCAY CARACNTTYYTNGGNATGGGNGTNGAYYTNGTNTTYCAYYTNACNCCNYTNYTNATHGCN GAYATGYTNATHATHAARMGNTAYTCNGGNGTNCCNTAYTCNGARATHGCNGTNMGNCAR CARGAYTGGATHGTNMGNACNMGNCCNYTNCCNCAYGARCCNCCNGARTTYATHTCNYTN TGYYTNCARGTNYTNGGNAGYGTNTTYYTNTTYGAYYTNTTYTTYACNGCNGTNCAYTAY GCNATGCAYMGNAAYMGNTTYATGTAYAARTAYTTYCAYTCNCARCAYCAYGAYCAYGTN GTNGTNCAYGCNCAYGTNACNAAYCARYTNTCNGTNGTNGARMGNGGNYTNCARGTNATH TCNGCNAAYTAYGCNYTNAARGCNTTYMGNTGYCAYCCNYTNTCNMGNYTNGTNTTYGTN CCNGTNTTYYTNTGGYTNYTNATHGARAAYCAYACNGGNATHGAYYTNCCNTGGGCNCCN CAYMGNYTNYTNCCNGGNAARGTNATGGGNGGNCCNGCNAARCAYTAYGCNCAYCAYGCN CARGGNCAYGGNCAYTAYCARCCNTTYTTYACNTAYYTNGAYAAYTGGYTNGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AGYTCNATGCCNGGNATHGTNCCNGCNTAYAARMGNATHGCNGTNGGNGAYGCNGTN GGNAARGGNGGNATHCCNYTNTAYCCNAGYAAY---YTNATGTCNCCNTAYCARCARCAR GCNGCNTCNYTNGTNCCNYTNCARCARCAYCCNTCNTAYATHCCNATGCCNTAYCAYYTN CCNTAYCAYCARCCNYTNGCNGGNCAYCCNCCNACNGTNCCNMGNTTYGCNTGYATHGAY YTNACNGTNGAYATHGGNGGNGAYGARGTNATHGAYYTNACNAAYCAYAAYAAYATHATG GAYTCNCCNGTNGTNATHYTNACNCARACNGAYGAYATHGGNCCNATHMGNMGNMGNMGN GGNAGYGGNMGNMGNGGNYTNMGNMGNTCNAAYAGYACNMGNCARYTNCARMGNGARGCN TTYACNTCNCCNCCNTCNMGNTCNGAYATGCCNTCNTCNTCNAAYGCNGGNCARYTNGAY ATHAAY---GAYAGYGAY---GAYGARYTNCCNGAYATHCCNTTYGARATHTCNCARGCN AGYTCNAARGCNAAYGCNAAYTTYATGACNTCNCCNCARATHAARGTNACNTGYCCNATH TGYYTNGAYGAYATHAARCARATHAARTCNAGYCARAARMGNATHATGTCNACNACNTGY GGNCAYGTNTTYTGYGARGAYTGYATHATHAGYGCNATHMGNACNTTYMGNTCNTGYCCN ACNTGYMGNAARTCNYTNTCNCARAAYAARATHCAYCCNATHTTYATHAGYCARTCNAAR TCNYTNAARGTNTCNGAYCCNGAYTCNTCNATHACNCCNTCNCCNMGNGARGGNTAYAAR YTNAARMGNCARAAYMGNAGYAARACNYTNCCNATGGCNAAYGCNGAR---GARGAYAGY TCNCCNAARGTNCARMGNGCNTTYTCNCAYMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARGTNYTNGGNGTNYTNGTNAGYAARGTNTCNGAYCCN GCNACNAARMGNYTNCAYTTYGARATHAARGGNMGNATGCARGAYGTNAAYGARATGAAR AAYATHYTNGTNAAYCAYCARGAYYTNYTNTCNTCNGGNGCNCCNAARMGNGGNACNACN CARTTYGTNCARTAYGCNGCNGAYTGYAAYGAYMGNTTYCCNTCNTAYTGG------AAR YTNAARMGNGARGCNCARCARTCNAAYMGNAARGARATGGTNGAYGAYAARGCNTTYAAR GCNATHGARAARYTNGTNCARGCNACNTGGAARCARAAYYTNGTNGGNCARGGNAAYGAY GCNGCNAAYATHCCNGCNAAYAGYAARATHAARGTNTTYAARATHGARMGNYTNGARAAY TCNTCNYTNTTYTTYAARTAYTCNATGAARMGNAARACNATHTTYAARGAYATGGCNTCN MGNGGNCARYTNTGYAARAAYGTNAARAARYTNAARGGN---AGYAARGGNGGNGTNGAR ACNATGAAYAAYYTNGAYGAYTTYGTNAARACNGAR---YTNTAYTAYGARATHAAYGAR GTNTAYYTNTTYCAYGGNACNAARTCNGCNACNATHAARTCNATHTGYGARCARGGNATG GAYAGYMGNYTNACNAGYGARCARGCNATGYTNGGNCARGGNATHTAYYTNGCNGARAGY TGYACNAARTCNGAYCARTAYTCNGCNCARAARYTNMGNMGNCCNCCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GAYACNGCNGARGCNYTNAAYGAY TTYTGGATGYTNCAYAARMGNAAYMGNYTNTCNCCNYTNTTYCARGAYATHYTNGTNGAY AARTCNYTNYTNMGNGARACNAAYTGYGTNAARYTNACNYTNMGNGCNATHYTNTGGGAR CAYGARGTNMGNGGNTGYAARGARGAYYTNMGNAARMGNCCNGARACNMGNACNAARYTN TCNAGYYTNGCNAARGAYYTNGCNATGGTNAARMGNGTNCARGARCAYCARAARTGYATG CCNGARAAYGTNGCNAARGCNMGNGAYGCNGARAGYCARTTYGARAARCAYYTNGGNGAR TTYATGYTNACNATHAARCARATHYTNCCNCARCCNACNCARGTNATHAARACNATHAAR GARTTYCAYACNAAYYTNAARATGGCNMGNGGNGTNAARAARGTNCARTTYGAYAARATH GAYCAYTAYYTNCARTCNYTNGARTTYTAYMGNAARGTNTTYCARGARGTNGARAARCAR ATHGTNCAYCCNYTNTGYCARGTNCARGCNTGYTGYGARAAYGARAARCARMGNAAYYTN AARAARACNATHAARAARTGYTGYTCNGARATGYTNGCNTAYYTNMGNCCNGAYGTNGAY YTNCARAARGTNMGNCAYAARGARTGGGARAAYAARGTNYTNCARMGNGARCAYGGNYTN TTYTAYGGNYTNATHAGYYTNGTNCCNATGAGYGTNGAYMGNYTNACNACNATHGAYTAY AGYACNGAYGARTAYATHAAYGAYTTYCCNGARATG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATHGCNATHGCNAAYGCNYTNAAYACNATGAARGCNGGNCARACNGTNCCNGTNCARYTN GAYGTNGCNTCNGTNAARTCNGGNGGNAARTCNGTNGARGARYTNACNGAYTTYTGYAAR MGNATHTCNGARAARGARCARGARAARYTNGAYAAYGCNGTNAGYGAYAGYAGYGARGAR GARGCNGTNCARAGYGAYGARGARGARCCNYTNATHCAYCAYCCNTTYAARGTNAARGAY GCNTCNTCNAAYATHGTNATGAAYATHMGNAAYGCNAARCARYTNCCNGTNYTNACNCCN TGYGARAARCARGTNCARCARGCNTCNYTNMGNYTNGCNTTYCCNGTNTCNAGYGGNTCN CAYCAYMGNGCNAGYGARTCNGARTGGGTNCCNGTNGARMGNACNACNGCNCARTCNACN TCN------------ACNGTNAGYAARGTNACNAAYTCNATHGCNTCNTCNGARTCNCAR CCNGARCCNTCNAAR---AGYATHTTYCCNAGYGARACNAARAAYATGGAYATHGGNACN ATHATHTCNGARMGNYTNCARGCNGTNMGNAARYTNCARGCNAAYCCNTAYGAYGTNCAR GCNYTNAGYAARATGCAYAARGCNCARGARAARGCNAGYCARTGGGCNCARTCNAARCAY YTNCCNGGNCARTTYATHGGNTCNACNGGNGCNCAYGTNATGTCNCARGARGARATHATG GGNGAYAARMGNMGNCARGCNTGGGTNAARAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNGTNGTNCARGCNGARGARYTNGGNTGY GARGGNAARGTNGARGARGCNCARGGNGTNATGAARYTNGTNGAYCARYTNAARGARGAY MGNCAYCARYTNGARATH---AAR---CCNATHCARGAYGAY---GGNCCNYTNATGAAR CARATGGARGTNTGYGAYGTNTGYGGNGCNTTYYTNATHGTNGGNGAYGCNCCNCARMGN CARGAYGARCAYYTNATGGGNAARCARCAYGCNGGNTAYGCNCARGTNMGNGCNGARATH GAYMGNMGNAARAARAARGTNMGNGAYGARACNGAYGCNMGNGARGCNAAYGARAAYAAR YTNMGNYTNGARMGNGARGARMGNGARMGNGARMGNCARMGNGARMGNGAYGARMGNMGN CAYAARGAYMGNGAYGTNGAYAARMGNMGNGAYMGNGAYMGNGAYMGNMGNMGNMGNAGY MGNTCNMGNAGYMGN------------GAYMGNMGNMGNTCNMGNAGYMGNGAYMGNMGN MGNCARMGNAGYTCNAGYMGNGAYMGNMGNAGYMGNMGNAGYMGNAGYMGNAAYMGNGAY ------------------AGYTCNAGYMGNGGNAARMGNTCNMGNMGNTCNTCNAGYMGN GAYMGNAARCAYGAYMGNMGNMGNTCNMGNGAYMGNAAYTCNMGNGGNMGNGCNMGNTCN GGNTCNGGNGARAARAARGARMGNATHMGNGAYGAR---GARTAYGARMGNAAYGAYCCN MGNMGNGARGAYGTNAARGAYAARACNAGYAAYGGNGAYAGYAGYGGN------------ ------------------------------------------------------------ ------------------------MGNTCNYTNYTNGGNYTNTAYAAYTGGAARTAYAAY GAYATHACNYTNTTYTCNAAYMGNAAYCAYCCNAAYGGNTAYTTYTGYGGNATHYTNCAR GARCCNGARTTYCARGTNTAYACNATHGGNCAYYTNAARGARGAYYTNGTNAAYATHCCN AARMGNGAYACNYTN---------------------------------ATGGAYTTYGAY TCNTCNTCNAARTTYATHGCNTCNYTNGCNMGNTTYYTNCARTCNYTNTGYAAYGGNTAY GTNGARTTYGAYAARGGNGTNGARGTNATHGGNCAYATHTAYYTNAGYGTNGAYAGYGAY ACNGGNMGNAARATHGAYTAYGTNYTNAAYGARAARGTNTGYAARAAYGAYAAYTCNGTN ACNTTYATHAGYAAYAGYTTYCAYGCNCARCCNGCNGARAARCCNAARCCNGCNCCNAAR AARTCNGAYTCNGARAAYAARAAYGARGAYACNGTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNYTNTTYGCNTGYTAYAAYGAYGGNATHATHAAYYTNYTNGARAARTAYTTYGAYATG AAYAARAARCARTGYAARGAYGCNYTNCARYTNTAYAARAARTTYYTNGTNMGNATGGAY AARGTNTCNGARTTYYTNAARGTNGCNGARAAYATGGGNATHGAYAARGGNGAYATHCCN GAYYTNGCNAARGCNCCNGCNAGYYTNYTNGAYGCNYTNGARCARCAYYTNGCNTCNYTN GARGGNAARAARTCNACNACNCCNACNGGNTCNAGYAARCCNTCNGGNTTYAAYGCNGCN YTNAAYAAYATGTCNAGYAAYACNTTYAAYGTNAGYGARGCNGARAARAARMGNATHYTN GARGARGARAAYCARCARYTNCARMGNCAYAAR--------------------------- ------------------------------------------GAYYTNGARMGNTTYYTN TCNYTNGCNAARGARGARGAYYTNGTNGTNYTNYTNMGNATHGGNCCNTAYATHTGYGGN GARTGGGARTTYGGNGGNTTYCCNGGNTGGYTNYTNACNGARAAYCCNAAYATGGTNYTN ATHACNAGYGAYCCNACNTAYATGAARTGGGTNAAYYTNTGGTTYCARGARATGYTNCCN AARGTNAARCCNCAYYTNTAYAARAAYGGNGGNTCNGTNATHATGGCNCARGTNGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGGCNGCNGTNGARYTNGAY CCNGTNTTYGTNAARGCNYTNAARYTNYTNCARTCNAARACNAARGAYAGYAGYGCNCAR YTNAARTCNATGYTNGAYGAYGCNATHGCNYTNMGNAARGGNYTNAARGTNCCNGCNCAR TCNGGNGAYGTNGAYAARACNGCNYTNTCNAARGCNAARCAYGAYGAYGAYGTNAARMGN AARGAYGGNGARAARMGNTCNCAYGAYAARTCNGTNAARGAYCCNTTYGARCCNGARGTN AARMGNTCNAARTTYGARTCNTCNAARCARAARGAYAARGAY---------ACNAARGAY AARGARAARGARMGNGARMGNGTNAARAARGAYAARGARAARAARGARMGNGAR------ GARGCNCARMGNCARAARGAYAARGCNGARAARGARAARAARGARAARGARTCNACNAAR CARGAYTCNGARATH------------ATHAGYGAYGARGARGARCCNGCNCARCARATG GAYGCNGGNGAYTTYGCNMGNGAYYTNGGNATHGCNTGYGTNGTNTGYMGNCARTTYGAY GTNAGYTCNGGNAAYCARYTNGTNGARTGYCARGARTGYCAYAGYYTNTAYCAYCARGAR TGYCAYAARCCNGCNGTNACNGGNCARGAYGTNAGYGAYCCNMGNTTYGTNTGGTAYTGY TCNMGNTGYACNAARAGYTTYAARAARATGATGGCNCARAARCCNATHAARTCNAGY--- AARCCNGTNGCNCCNYTNTCNACNACNGCNAARGARTCNACNTCNACNACNACNAARATH AAYAARCCNGARTCNGAYTCNGGNAGYCARGCNTTYMGNMGNATHGAYCCNAARGCNATH GTNACNCCNAARGAYACNGGNAAYYTNACNTCNTCNTCNAARGCNATGGTNGGNYTNGCN GGNYTNGCNGCNAAYYTNACNAARCCNMGNGGNGARTCNAARAAYGCNACNTCNTCNAAR AARACNGARCAYAARGGNGAYAGYGCNAARTCNTCNAARACNGARATGAARTCNGGNTCN AARCARGARAGYTCNAGYAARCARTCN---------------CARTCNTCNTCNTCNTCN TCNTCNTCNAARAGYGARGCNMGNAARGCNGAYAGY---GTNAARTCNTCNAGYAARGAR GAYGAYTCNAARAGYAGYAARACNAAYGARAGYTCNTCNMGNAARGARGARAARAARGAR AARGARAARGGNGAYTCNTCNGCNAARTCNTCNAARGARGAYAAR------AARTCNGAY GCNATHAARTCNTCNCCNTCNCAYTCNGGNTCN------------------------TCN AGYAGYTCNCCNCCNGCNGCNCCNGTNTCNCCNGTNACNCCNACNACNCCNTCNAARAAY AGYAGYGGNAGYAGYAGYAGYAGYAGYAGYAGYAAYAARCARGCNGTNGCNAAYYTNTCN ATGGTNACNGCNAAYAARMGNATGCARATGATGAARAARAARGCNCARACNAARCCNCAR GARAARAARGTNCAYATHAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GTNAARGGNAAYACNAAYMGNGAYYTNATHCARATHAARACN GCNGAYGARAARGARGTNCARMGNMGNATHGAYTCNTTYATHMGNAAYAARMGNAAYGAR GTNAAYGARMGNAAYGTNMGNGARTTYATHTCNCCNTTYGGNTCNGAYYTNGAYGAYAGY TGYGCNMGNGTNGARGCNGTNTAYGTNCAYMGNGARGGNATGAARAGYCAYATHAAYYTN AARACNGTNCARAAYGTNTAYGGNCCNCARACNMGNYTNMGNCCNGAYYTNAGYGAYGAR ATGCARTCNTGGATGGCNTCNGCNGAYGTNCARMGNGCNGARGCNGTNGARGARMGNYTN GCNAAYATHGARTCNCAYYTNAAYGTNACNGAYGGNGCNGGNGAYATHTAYAARMGNATH AARTCNYTNGARGARMGNATHAGYTTYYTNGARGGNATHTCNCCNGARTAYTTYACNCAY GGNATHCCNCCNGGNAARCAYMGNAARTCNAARCARCCNAARCARGARAARAAYGCNYTN GTNCCNACNAARCARACNGCNGCNGARGTNTCNGGNCAYCARACNGARATHGTNGTNAAY AARTTYGARGAYCAYYTNTTYATHATHGCNACNCARTTYCARAARYTNGGNACNGTNATH GARGTNTCNMGNGAYGTNGTNAGYGAYGARGTNCARGGNCAYATHCCNYTNTTYTCNACN AAYGTNYTNYTNGGNAARGAYGARCCNYTNACNCAYGTNATGGCNAARACNATHGTNACN GCNYTNAAYCCNCCNATHCCNGTNATHYTNAGYYTNGCNYTNAARGTNACNACNCCNGAR GCNGTNCARACNATHATHGARYTNATHAARTCNTGYYTNATGGCNAAYAAYATHCAYTTY GARGCNMGNMGNMGNCARATGGTNYTNGAYMGNGCNTGYAARGCNAARMGNGARATGCCN YTNGCNCAR------AARGCNACNGCNCCNYTNACNGARGAYGGNATHAAR---CCNGAR ACNGTNATGTGYACNGAYCARGGNCARTTYTAYCARACNMGNCCNAGYATHCAYGTNTGG ACNGGNCCNGARMGNAAYMGNMGNACNTAYGAYMGNAGYMGNGARGGNCCNGTNYTNGGN AGYTCNTGGMGNCARYTNGARMGNGARATGACNTAYMGNCARAAYTGYYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGCCNAAR TTYTAYGARGAYGTNGARGARAARAGYAAYAARCCNAARYTNGCNTGYGARGGNATHMGN GAYGAYYTNYTNGARTGYYTNYTNAARAGYGAYTGYTGYAARAARGAYAARAAYACNCCN MGNCARTGYATGGGNAARATHGGN---------GAYCCNTCNGTNCCNGAYGARTGYCAY AARYTNMGNGTNGCNTTYYTNGARTGYMGNMGNTCNATGYTNGAYATGMGNACNMGNTTY MGNGGNMGNAARGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AARAARAARGTN TAYATHAARAGYYTNGARGAYGARATHAGYACNYTNAARACNGAYAAYACNAARYTNAAR TCNGARAAYACNMGNATGCARTCNTCNATGACNGCNYTNGARGARGARGTNGAYTAYYTN AARTCNGTNYTNGTNAAYTCNAGYGCNYTNTCNGGNYTNYTNAARAAYATHTCNGGNGTN ACNGARGTNAARYTNTCNGCNTCNATHGTNGGNMGNAARMGNTCNGCNACNGGN---GAY GAYCAYAGYTAYAAYATHGTNGARAGYGTNCCNGARAARMGNGCNMGNMGNATHAAYGAY AAYYTNMGNAARGCNGGNGTNTGYYTNCAYGTNAAYGGNGGNTCNGCNTGYYTNGARTTY TGYGCNCAYTGYTCNAARYTNGCNAARAARTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARGTNATHACNAARMGNGTNAARGARATGGGNGAR YTNTTYTGYCARCAYTAYATHAARTCNACNGARAAYGAYCCNGGNGCNCAYATHGAYTTY GCNMGNMGNMGNYTNCARYTNGGNGARAGYYTNTAYTTYAARACNYTNGARGARATHGTN GAYGGNGARMGNMGNMGNYTNGARGGNAARTCNGTNGAYYTNYTNGCNYTNYTNGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AGYTCNGTNGGNGGNCAYATHGAYCAYAGYAAYCCNGGNGGNACNAAYTAYGGN GTNCAYGGNAGYCAYACNTGGTCNCAYGGNGGNGGNAGYAARACNACNYTNTCNGGNGGN TTYGAYCAYAGYTCNCAYGGNGGNAAYAGYGTNGGNATHAGYGTNACNCAYAGYATHGGN AARMGNYTNGCNGAYAAYAAYGTNTTYGTNGCNGTNCAYTCNGGNGCNGGNAAYCAYTCN AARGCNAAYGARGARCAYAAYAARACNATHTGYAARMGNGCNTGYCARCARGCNATGGAR YTNYTNMGNTCNAGYAARTCNGCNYTNGAYGCNGTNACNGCNGCNGTNGTNTCNYTNGAR GAYGARGAYAGYACNAAYGCNGGNTTYGGNTCNAAYYTNACNGTNCARGGNAAYGTNGAR TGYGARGCNTGYGTNATGGAYGGNGCNTCNYTNTAYTTYGGNGGNGTNGGNGCNYTNTCN GGNGTNAARAAYCCNGTNAARGTNGCNGGNYTNYTNGTNAARGARCARACNGARGGNCCN YTNCCNTTYGGNMGNGTNMGNCCNAGYGTNYTNGTNGGNAARGGNGCNMGNACNTTYTGY GTNGARCAYGGNATHGAYGTNAAYTAYAAYATGATHTCNAARTCNTCNTTYAARACNTAY AAYMGNTAYAARMGNAARTGY--------------------------------------- ---------------------GGNAARMGNMGNAAR------------ATHGARCAYGAR ACNAARGARAARAAYTCNACNCCNATGGAYGCNGARGTNYTNTCNCAY------------ TTYGTNCARGAYACNGTNGGNGCNATHTGYGTNGAYCARGAYGGNAAYGTNGCNGCNGCN TCNTCNAGYGGNGGNATHTGGYTNAARCAYCCNGGNMGNYTNGGNCCNATHTCNATGTAY GGNGCNGGNTGYTGGGCNCARAAYYTNAARTCNGARGAYAARCCNGGNGTNGCNGTNGTN ACNTCNGGNTGYGGNGARCAYATHATGCARACNGTNYTNGCNAARACNTGYGCNGAYGGN ATHMGNTCNTCNGARAAYYTNTCNCARACNYTNCCNCARGTNTTYAARACNGAYTTYYTN GARTCNGARTTYYTNTCNTCNACNCCNGARAARYTNAGYGGNGCNYTNGCNYTNAARTTY AGYGAYATHTCNGAYTCNAARGARGTNGARYTNTGYTGGATHCAYTCNACNGCNAGYTTY TGYTTYGCNTTYATGGGNGGNGARCARAARCCNCCNAARGCNGTNATGTCNCAYYTNGAR GARCARTGYAARCCNGGNCAYTCNTTYACNATGGGNGGNCAYYTNGTNTTYYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNGAYMGNTAYYTNGGNGTNTCNTTYGTNTCNYTNGCNATHCCNTTYGCNTCNGTNYTN GCNATHGCNGTNTTYGCNYTNGAYTAYTTYTCNCCNTGGTAYACNGARYTNCCNGARTCN YTNYTNGGNGARGGNATHATGAARACNGGNGCNTGGCCNCCNTTYGTNGCNGGNATHATH GTNGGNGCNYTNCARATHCCNATHGTNYTNGCNAAYATGAAYACNYTNGGNACNTCNTCN AGYTAYGTNTCNYTNGTNTCNCARATHYTNCCNYTNMGNGCN---------GGNAGYTCN GGNGARAAYTAYYTNAARCARTTYTGYAGYGGNATGAARAAYTGGTGGCARGTNTTYTAY GTNGGNGGNGCNGTNYTNGGNGGNTAYATHTCNGCNTCNGCNTCNGGNACNYTNAGYACN GTNCCNGGNGTNCCNTGGTAYCARGCNTTYGGNGGNGGNATGATGYTNGTNTAYGGNTCN MGNYTNGCNGGNGGNTGYACNAGYGGNTAYGGNYTNTCNGGNATGGGNYTNATGGTNATG YTNTCNTTYATHGCNGTNCCNGCNATGTTYGGNTCNGGNATGGCNACNGCNTTYTTYATG MGNGAYATHYTNAARYTNGAYATH------------------------------------ ------GTNMGNACNGCNGCNGCNGTNTCNGARAAYAAYAARCARCARGARATHAGYACN GTNATHACNAAYTAYCARCARGARGTNGCNAGYYTNCARCARYTNYTNAARGARGCNGCN GAYACNGCNTCNGAYAAYACNGCNGCNCARTAYGARTCNGARMGNAAYAARYTNGTNACN YTNAAYGARAAYTAYGARGARGARATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNGAYTAYMGNGGNMGNGGN---MGNAGY AGYMGNGGNMGNGGNGGNCCNATHMGN---GGNTCNTTYMGN---GGNMGNGGNAGYTAY ATGGAYMGNGAYAGYGGNGGNMGNGGNGGNGGNTTYMGNGGNMGNGGNGGNTTYTCNMGN GGNMGNGGNGGNCCNCCNMGNAGYMGNGAYGAYYTNTCNCCNCCNMGN------ATGTCN MGNAGYTAYGARTCNTCNGAYMGNGGNMGNGGNCCNCCNCCNAGYMGNMGNAAYGAYMGN TAYGARGAYAGYTAYGAYMGNGGN---CCNACNATGMGNATGAARGAYYTNTAYTCNTCN CCNCCNMGNGAYTCNGGNMGNAGYTTYGAYMGNCAYTCNCCNCCN------CCNMGNMGN GARMGNGAYTAYGTNCCNMGNCAYAGYGAYCAYTTYAGYTCNTCNMGNGGNGAYTAYYTN TCNCCNMGNAGYTAYAGYCCNCCNMGNGAYACNGGNTAYAGYTCNTCNTAYAARGAYTCN TAYAGYTCNGGNCCNMGNGARGARMGNMGNCCNATGMGNGAYTAYGCNCCNMGN------ ------------ACNAGYGAYTAY---GAYMGNMGNGAYTTYMGNGAYACNCCNMGN--- GAYTAYGGN------TCNMGNGAYTAYCCNCCN---TCN---MGNAAYGGNGAYTTYMGN GAYTCNATGAGYAGYMGNGAYTTYMGNGAYGCNCCNMGNAGYGAYMGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CARCAYATHTTYACNMGNATG GGNYTNACNYTNAARTCNYTNYTNTCNGCNACNMGNGCNACNCCNGCNCAYMGNYTNGCN MGNAAYCARGGNGARAARGGNGGNGGNTAYAARYTNAAYTAYMGNTTYTAYYTNGGNCCN CCNAARACNCAYATGYTNGGNGARGAYTTYAARTCNGTNMGNGCNGGNGCNYTNCCNTCN GCNTAYGGNYTNYTNAAYATHAAYGTNGCNTAYMGNACNAARYTNYTNYTNTCNCCNGAY ACNACNACNTCNTCNTCNAGYATHATGCARGTNACNGAYGAYCAYTTYATGAARGARAAY MGNAAYAARCAYACNYTNCAYATGTAYTCNGAYCCNAARCCNTGY--------------- ---CAYCCNTCNYTNTCN------------------AGYCCNGAYAAYATGGCNGCNATH CCNTAYCAYTAYACNGTNTCNCCNTCNTCNCAYGGNACNGAYGARGAR---ATHATGTCN AARATGTCNGCNGAYCCNGGN------ACNTGGCCNYTNGCNAGYGTNYTNAAYYTNGAR GARTTYCCNGARCCNGCNGTNGGNGCNTTYTCNGCNCARMGNCCNCARGCNTTYMGNGTN GARGARAARGAYYTNCCNTTYGARGGNYTNATGAARMGNAGYATGATGGCNMGNYTNGAR CARAARCARAARCARGARATGMGNGARMGNGGNATGGAY------AGYGGNTTYGGNACN TCNCAYGARATHMGNAARGTNGGN------GCNGCNGARGARGARAARGARAAYYTNGAY GTNYTNAAYACNTTYTCNAAYAAYYTNCCNYTNGARGARGAYTAYGTNATHGTNGAYCCN CCNTTYGCNAGYGCNGAYGAYCCNMGNGAYGTNAARTCNTTYYTNGGNGTNATGTTYMGN GCNCCNCAYYTNTAYGARGCNCCNGAYGTNMGNYTNACNGTNGAYGAYTAYYTNATGGAY GTNGGNGARATGATGACNMGNYTNGARGARGAYATGCCNCARYTNGAYGARTTYTGYCAR TCNGTNATHGARTTYAGYAGYACNGARGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TAYCCNGGNAARGGNCCNGGNTTYMGNGTNATGTTYTGYMGNGAYACNTTYTAY CAYTCNGARATHGAYGAYYTNGAYATHMGNATGGAYCAYATGATGCCNACNYTNAARAAY MGNCCNMGNGGNAARAARAARAARGARYTNTCNMGNAARGAYTCNCARCARGAYTCNGAY AGYACNGARGARATGTTYGCNAAYGTNGCNCCNTCNGTNTCNAGYTCNTCNMGNCCNMGN MGNTCNACNGAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNYTNCCNYTN TCNACNTCNACNYTNGTNATHAAYMGNATHATHACNYTNTTYGCNMGNAARTTYGTNGCN YTNYTNGAR------GARYTNAAYGARAGYGCNGAYYTNTCNCARGARGCNYTNAARTGY YTNAARAAYTTYTGGTCNYTNTGYTCNAAYCARCARAAYGTNATHTCNTCNTCNGARYTN TTYGGNMGNTGGGAYACNTGYYTNYTNGARTCNATHACNCCNYTNGCNTCNATHTTYGTN GAYYTNTCNATHGCNGCNCAYGGNCAYAAR------GARAAYCARYTNTTYTGGTCNAAR AARYTNTAYAGYTGGYTNAAYTTYGAYYTNCCNGARMGNGCNGTNAARGTNGCNYTNYTN GARGTNACNGGNCAYACNMGNGAYGGNGCNGAYATHGTNGGNCCNYTNYTNMGNAARGTN YTNTCNCARCAYTTYGAYGCNGAYTCNAAYCCNGARTAYYTNYTNCAYTTYYTNYTNGTN AARAARTGGCARGGNYTNGARGCN---GTNGCNGAYATHGCNGARACNTCNAARTCNYTN AARGCNCCNGCNTCNTTYYTNGAYTGGYTNAARACNTAYTGGAARGAYGCNAGYGAYTAY ATHCCNGARGAYAARAGYYTNAARGGNATGATGGTNAGYCARTTYYTNYTNGAYYTNGAY ACNGAYGARGTNYTNGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TGYGGNCARGGNACNAARAARMGNAARMGNCARTGYYTNGGNCARMGNTAYGGNGGN AARTCNTGYCCNGGNGARGAYGARGAYCARGTNCCNTGYAAYAARGARCCNTGYCCNGTN YTNCCNMGNCAYTTYCARATGTCNCARTGYAAR---AGYAAYTAYACNTGYGCNAGYGGN AARATGTGYACNNNNTCNAGYCAYMGNTGYGAYGGNAARGTNCARTGYCAYGAYGGNAGY GAYGARATGAARTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGCARCCNGAYYTNAAYAAYGTNATHACNGGNCCNGTNGCNAARCAYTTYTTYGARAAR TCNAARYTNCCNGTNATHGARYTNTCNAARATHTGGCARYTNTCNGAYYTNAAYTGYGAY GGNGCNYTNTCNGTNGARGARTTYTGYATHGCNATGCAYYTNGTNGTNYTNMGNMGNAAY GARATHGARYTNCCNGAYMGNYTNCCNYTNGARGAYGGNAARCCNGTNGTNGARAARGAY GARCAYGGNATGCCNTTYTTYAARGTNMGNTTYAAYATGAARGARTAYMGNCCNGARGAR GTNAAYGTNAARATGGAYACNAAYAARATHATHGTNTCNGCNMGNCAYGARGARAARACN GGNGGNTCNTCNGTNAGYMGNGARTAYAAYMGNGARGTNAAYGTNCCNGCNGARGTNGAY CCNYTNGCNYTNCARTGYYTNTTYCARCCNGAYGGNTAYYTNGTNTTYAGYGCNCCNYTN CCNGCNCCNAARTAYGAYGCNATHAARGARGCNCCNGGN---CAYTCNTCNCCNTCNGTN TCNTCNAARTTYAGYAGYYTNAAYTCNTCNGARAAYCCNGAYCAYATHGTNCCNATGTTY MGNCCNCCNCCNGAYATHAGYAARYTN---------------YTNGAYGGNCCN------ ---------TCNCCNATGGTNAARCCNCCNCCNTTYACNAAYYTNAGYTCNACNTTYCCN GCNGGNCCNATHTTYCCNGAYTCNTCNAARCARATHCARYTNAGYGTNCCNACNGTNACN TCNCAYGAYGGNAARTTYCARYTNACNATGCCNATHGAYGAYTTYAARCCNGARGARYTN ACNGTNAARACNCARGAYMGNAAYGTNATHATHTGYGCNMGNMGNGARGTNATGAGYGGN AGYMGNAAYCAYACNATGGARATGAAYMGNGARCAYGGNYTNCCNGAYAAYGTNGAYCCN YTNACNGTNAARGCNTTYTTYACNGAYACNAAYATGYTNATHGTNGARGCNCCNTTYYTN MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARTTYACNGAYGAYGARATH MGNGARGARYTNGCNCAYYTNGGNTAYCAYGAYGTNCCNCARGAYAARYTNGARGGNTTY AARAARGAYYTNATGACNYTNATHACNMGNGARMGNAGYAARTCNAAYTCNYTNAAYAGY AGY---------------MGNACNACNGARCCNGARAGYMGNGARMGNGAYCCNMGNCAR CARCARTTYACNAGYAARGGNGAYTTYACNAAYCAYGGNAAYCARTGGYTN---GGNAAY GGNTTYCAYGARGAYTGGMGNTAYCARGGN------------------------------ GARAARGARGGNCCNGTNAARCCNCARACNATHTCNMGNCCNCARACNGCNCCNGARAAR CAYGGNCARCARMGNMGNGARMGNGCNGCNGARGGNTAYTCNGAYTTYGARYTNCCNTCN TCNTCNMGNGCNCAYCARGARMGNAAYCARAGYTGYCAYMGNGAYGAYGARTCNTCNGAR GCNGGNTCNGARAGYMGNTGYATGAARMGNAARACNTCNMGNAARACNTCNGAYGGNTGY MGNYTNATHGAYGARTCNTTYACNGAYACNGAYTCNGGNGTNTTYGARATHTAYGARMGN ATHAARAAYYTNGCNATGMGNGARTGYGARTGYGGNAARAGYMGNTCNAARTCNGGNGAY GTNGARCCNCCNTAYMGNATHAARGGNAARGTNAAYAARACNCCNTCNGTNATHAARAAR YTNGARCCNCCNCAYACNMGNAAYYTNGTNMGNGTNGAYGTNAAYYTNMGNCAYCARATG TAYCARGAYGCNTGGAARGCNMGNCCNCCNATHGGNGAYGAYATHMGNATHAAYYTNMGN AARTCNGTNCAYACNAARATGYTNAARMGNGAYGARTTYAARYTNAARCARAARGTNTTY GTNCCNAAYYTNTAYGTNCCNCCNCAYCARAARYTNMGNAARGAYGTNMGNTGGAARGTN AARCARGCNTGYGARAGYTAYGARYTNCCNGCNCAYGGNTTYTAYCAYGAR---ATGMGN AARGARGTNGARAGYAAYMGNYTNAARACNAAYCARYTNCAYATGGCNAAYAARGARTGG AARGAYAARTGGGAYTTYYTNAARAARCARAARGARGAYGARAAYYTNCARYTNMGNGTN CARGTNGCNCARYTNMGNGARGARMGNGAYMGNGCNMGNMGNGAR------------ATG ACNTCNYTNAARGARGARYTNATHCARGCNAAYYTNTCNAARMGNGARYTNGARAARTCN TGYGCNGCNYTNCAYGCNGGNMGNTCNCARGARAARCARYTNYTNGARAARYTNAARCAR GAYTAYGGNAGYYTNCAYCARGARAARMGNGCNYTNGARATHGARGTNGARAGYYTNMGN ATGAAYAARCCNGARAAYCCNMGNTGYCAYGARMGNGGNAAYTCNGARATGGARATGGAR YTNTCNATGGTNAARMGNCARGTNTCNYTNTTYATGGARGAYTTYAAYAARGARCAYGAY GARMGNYTNGCNYTNGARGCNAARYTNCARAARGARAARGARTCNAAYCAYAGY------ ------YTNGARAAYAARYTNAARAARACNCAYGTNYTNYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TCNCCNGGNGGNAGY GTNYTNAGYGTNMGNTGYTCNCARACNTTYTAYMGNAARACNGCNYTNGTNAGYGTNTTY GGNGTNCCNYTNTAYTAYACNTCNAAYTCNCCNMGNACNGTNATHCARCCNAAYGTNCAY CCNGGNGARTGYTGGGCNTTYTGYGGNAGYTCNGGNTAYGTNGTNATHCARYTNTCNGAR TCNATHCARCCNACNGGNTTYACNYTNGARCAYATHCCNMGNAGYYTNGCNCCNTCNGGN ACNATHGAYAGYGCNCCNCARTCNTTYACNGTNYTNGGNYTNTCNTCNGARGGNGAYACN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARTAYAARTGYCCNTCNAGYYTNACNCAYAARTTYTCNGARYTNGTNATHYTNGAY CAYTGYACNAAYAARTCNGAYTAYMGNYTNCCNYTNTCNAAYTCNACNGTNGCNTCNATH ACNGAYCCNAARATHCARAAYGARGCNACNGARATHAAYGAYCCN------------GTN CCNTCNCARTAYACNCCNAARGARTCNAARGARATHYTNAARATHMGNCAYAARAARATG AARAARCAYAARYTNAARAARYTNMGNAARMGNATGTAYTTYGTNTGGMGNAARCARAAR ATGACNMGNAARGCNAARMGNGAYACNGTNTAYTGGAARGARATHAAYGAYATHAARAAR GARGGNGARGAYTTYGAYGCNGARTCNTTYGTNAARGGNGARYTNGARAARGCNMGNMGN GGNGGNTAYTAYATHAAYGTNTTYCAYTCNAAR---TGGCARGARTCNMGNGAYAGYTGY AARTCNGARGGNGGNGAYYTNATHTCNATHACNAAYTCNGARATHTTYTAYACNGTNGTN AARGTNYTNAARTGYMGNTGYTGGGTNGGNYTNCAYGAYAGYAAYAARAAYGGNACNTGG ACNTGGYTNGARGGNGAYACNCCNTTYGAYGAYYTNTTYTGGAGYMGNGGNGARCCNAAY AAYCAYMGNGGNATHGARTAYTGYGGNGARGTNGAYAAYTTYMGN------YTNAARYTN AAYGAYAARMGNTGYAGYMGNAARMGNCAYTAYATHTGYCAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARGTNYTNACN ATHGTNAARTCNGCNTTYYTNYTNATHTTYATGAGYYTNGTNTTYCAYTGYGCNGCNGTN YTNTTYGGNGCNCCNGTNTTYATHTCNGTNTCNGARACNTTYCAYTTYGCNATHYTNATG ACNATHTTYGTNTGYYTNCCNTGYTGYYTNGTNGCNGGNCCNAAYYTNGAYAARTGGYTN GAYATHTTYACNACNGAR---MGNGARCCNGGNYTNGARACNGTNGTNTTYYTNAGYAGY YTNGGNGCNYTNYTNGGNGCNTGGYTNGGNGCNATHCCNATHCCNYTNGAYTGGGAYMGN CCNTGGCARAAYTGGCCNGTNACNTGYTCNATHGGNTGYATHTCNGGNTAYTCNGTNGGN YTNTTYATHGCNTCNYTNTAYYTNCCNCAYCARTAYAARGCNYTNTTYAARTCNAARYTN ATGYTNATHATHCCNGGNAAYCCNGGNGTNCCNACNTTYTAYGARGAYTTYATGMGNGAR YTNTAYGAYCARTCNGGNGGNCARATHCCNGTNTGGGCNATHGGNCAYGCNGTNCAYACN CARCCNCCNAAYGARTCNYTNAGYYTNAARGAYATHGTNGCNCCNGAYGARGARATHTAY GGNYTNGARGCNCARATHAAYCARAARGTNGCNTTYATHAARGARCAYGTNCCNCCNGAY GTNAARYTNATH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AGYTAYGCNYTNYTNTCNAARTAYGARTGGATHCAY AAYTTYCARGTNATHGAYATHTTYAAR---GGNGTNYTNTCNAARATHCCNGCNGAYTGG TAYTCNTGYYTNGTNCARYTNACNACNGARCARYTNAAYGARGTNCCNTTYYTNGGNGGN AAYAGYMGNYTNAARTAYCCNGAYTGGCCNTCNTCNYTNCAYGCNTTYYTNYTNGAYTCN AGYCARYTNTCNAAYYTNMGNAAYCARAARCCNGARGTNAARCCNATHGARATHAGYTCN AAYATGGCNMGNGGNATGAAYAGYAARAARMGNCAYGARGTNACNMGNATGGCNTCNYTN GTNTAYGARGTNGCNACNGARACNAAYTGYAAYGTNGTNATHGAYGTNGGNTCNGGNYTN GGNTAYYTNGAYCAYGTNYTNCAYCARAARTAYGGNYTNAAYGTNYTNGGNATGGARACN GTNCARAGYCAYGCNTCNGCNGCNGARAARMGNGCNGTNAARCARGGNATHATHTGYAGY GGNATHAARAGYYTNCARAGYCAYATHGARGAYGAYAARGAYTCNTAYACNGCNTTYGTN TCNAARGTNGARTCNGCNTGYCCNAGYYTNCARTGYGARTGYGCNAARMGNYTNACNGGN GAYYTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNCCNTCNATGATGTCNTAYTTYCCNYTN AGYGAYYTNGGNMGNCARACNTAYAGYGARTGYATHCARAAYCAYGGNAARCCNTCNGTN ACNCCNTGYACNYTNMGNYTNGGNGCNCARGARACNAARTAYMGNTGGMGNGARCARACN MGNTCNGAYCAYGARTCNCAYACNAAYCAYGTNGCNTTYMGNGGNYTNYTNAGYYTNACN GAYGARGAYGARGGNCAYATHMGNCARAARGTNMGNMGNTGYAAYTTYGAYTCNTTYCAR AGYTTYATHGAYTCNTTYTAYGAYTCNTCNTAYGARAGYCCNTCNACNMGNGARAARAAR TCNGGNYTNYTNTCNYTNTAYAAYCARTAYAARAARGARTTYGAYGCNATHGARATHATH ACNYTNYTNCARGTNATHYTNCARCCNGTNATHGARACNYTNYTNTAYCARGAYMGNGCN CARTGGYTNAARGARCARGGNCAYAAYAAYGTNAARATHGTNCCNACNTTYGAYGARATG ATHTCNCCN------------------------------YTNTGYCARCARTGYGTNCAR AAYTGYGGNTCNAGYATGAGYTAYTCNACNTCNACNYTNTTYTCNCARAAYTTYAAYAGY MGNYTNAARTCNGCNGCNAARAGYTTYTGYAARAARATHGAYATHATHTCNCARYTNYTN TCNAARCARTGYAAYYTNGTNATHGCNCARMGNATHMGNMGNTCNTAYCARATHYTNYTN YTNTAYMGNAAYATHTAYGGNGARCAYYTNYTNAARGARAARGTNGCNTCNCARYTNAAY AARATHMGNAARAARCCNYTNATHGCNYTNYTNTCNGCNTCNATHTTYAAYTGGGAYAAR GARMGNGTNACNGAYGAYGARATHAAYAARTGYTAYCARGARGTNGAYGCNGTNGAYMGN YTNGTNMGNAGYAGYCARYTNYTNACNGARAAYCCNACN--------------------- ------------------------------------CAYGAYTGGGARCARATHGTNGAY AARGAYACNTTYAARGTNTGGMGNCAYCARYTNCCNAAYTCNGARYTNTAYGARTAYMGN GTNYTNGGNCAYTTYAARGAYATHCCNGCNMGNGCNTTYTAYAAYACNCARGTNGAYGTN TCNTAYTGGAARGAYTGGGAYAARCARACNATHGAYGTNAGYGTNGTNGAYAARGAYGCN AARACNGGNTCNGARATHATHCAYTGGYTNTAYAARTTYCCNTAYCCNATGTAYCCNMGN GARTAYGTNTAYGTNMGNMGNTGYATGATHGAYAARAAYAARAAYACNATGGTNATHACN GCNMGNGCNACNGAYCAYCCNAAYTGYCCNGTNAAYAGYTCNAGYGTNMGNATGGARACN TAYACNTCNCARATGGTNATHACNCCNTAYACNGGNTTYGAYGARAAYGGNTTYTCNTAY GTNATGTCNTAYTGYGAYGAYCCNCARACNAAYTTYCCNCCNATGTGGTAYAAYTAYGTN GCNAGYTCNGGNTGYCAYGARTTYYTNGARMGNATHCAYMGNGCNGCNYTNAARAARCAY GARAARACNGCN---GARATGACNACNAAYMGNATHGAYCARGGNACN---ACNYTNTAY CCNGGNATGGTNCAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARCCNAGYAGYATGTCNAGY AARGCNCARGCNACNCCNGTNGCNTCNTCNACNCCNGARATHTCNGTNTCNGARGTNATH ACNGCNAARACNAARATHGCNGCNCCNTCNYTNAARTCNGAYGARYTNTCN---GARGAY AAYGAYGARAARGARCARTAYGARYTNGAYATHAARATHACNGARAAYYTNAARATGGGN GAYGGNATGTCNGCNTAYATGGTNTTYAARATHGTNTCNAARACNACNAAYCCNGCNTTY MGNTAYCCNGARAAYACNGTNYTNMGNMGNTTYAGYGAYTTYYTNGGNYTNTAYTCNAAR YTNGCNGARAARCAYGTNCCNYTNGGNATHATHGTNCCNCCNGCNCCNGARAARAGYGTN ATHGGNATGACNATGGTNAARATGTCNAARGARGAYTCNGGNTCNTTYGAYTTYATHGAR MGNMGNAARGCNGCNYTNGARMGNTAYYTNATHMGNACNGCNTGYCAYCCNYTNYTNGCN GCNGAYTCNGAYTTYATHGARTTYYTNGARAARGAYGGNGAYYTNCCNAARGCNACNAGY ACNTCNGCNYTNAGYGGNGCNGGNGTNATGMGNYTNTTYCAYAARGTNGGNGARTCNYTN GARAARATHACNYTNAARGTNGAYGARAGYGAYGARTGGTTYGARGARAARCAYCARCAR ATHGARGCNYTNGAYYTNCARYTNNNNAARYTNCAYTCNAGYYTNGARACNYTNGTNAAY TTYMGNMGNGARYTNTCNAGYAGYACNGCNGTNTTYGCNAARAGYGCNGCNATGYTNGGN AAYGTNGARGARCAYACNGCNYTNTCNMGNGCNYTNTCNCARYTNGCNGARACNGARGAR AARATHGARYTNGTNCAYAARGAYCAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARTGYCCNCAYGARGGNTGYGAYAARAGYTTYCCNTTYCCNACNGTNYTNAARMGNCAY YTNAARATHCAYCARGGNTAYAARTGYGARYTNGARGGNTGYGGNCARGTNYTNCCNACN TGGACNAARYTNMGNAARCAYMGNGCNGTNGAYCAYMGNAARAAYYTNGTNTGYCAYATH TGYCARACNACNTTYTCNACNAGYCARAAYYTNACNCARCAYYTNAARATHCAYYTNCCN GGNMGNGAYTCNGTNATHTGYCCNMGNGARGGNTGYACNMGNACNTTYYTNTAYAARAAR AAYYTNACNCARCAYATHMGNTCNTTYCAYGARGGNAARCARGTNTTYATHMGNAARAAR AAR---ATHMGNAARAARAARGARCCNACNGGNMGNMGNATGCCNMGNAARATGTCNGCN GCNGCNAARYTNTCNGGNYTNGAYYTNACNAAR--------------------------- ---------------AGYCARATGAAYGGNGAYGGNGAYMGNCARGTNYTNGCNCCNTCN GARGGNCCNMGNGARGAYYTNATHAAYACNGCNATHAARTTYYTNCARAAYCCNAARGTN ATGGGNAGYCCNYTNCARCARAARAARGCNTTYYTNAAYAARAARGGNYTNACNCARGAR GARATHAGYYTNGCNGTNGTNMGNGCNGGNGTNACNGAR------ACNACNGAYTCNACN AGYGGNATGGCNGCNMGNCCNCCNCCNGGNTAYCARCCNGGNATGATG---------GCN CCNGCNGCNTAYAAYCCNATHTAYCCNCCNATHCCNCCNCARTCNMGNTGGACNCARYTN MGNGAYYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CAYGAYTTYGAYTGYGTNGAYAARGARCAYGAYATHACNGCNAAR ATHGCNMGNTGGTGGMGNMGNMGNMGNATHCARGGNTTYGGNCAYAGYACNCCNAARTGY GGNCCNAAYTCNATGYTNCARCAYATHTCNMGNYTNCCNGARTGYMGNACNTAYYTNAAY AARGARMGNMGNMGNYTN---YTNGGNYTNATGGARATGTCNGGNAARAARGCNGAYATH TAYGCNGCNYTNGCNAGYYTNGAYGAYATHATHGGNGAYATHTCNTCNGCNTAYAAYTTY ATHAARCARGCNGTNCAYTAYGARCCNTCNTGYCCNGARTAYYTNTGGYTNMGNGARAAR ATHTCNMGNCARTGYTGGATHYTNMGNAARCARAGYGAYGCNMGNACNCAYATHGARAAR AARGARYTNAARTTYCCNTCNATHATHGARGTNCCNMGNGTNTCNGGNAARGAYYTNAGY GTNTCNGAYTTYCARAARAARTAYYTNGCNGCNGGNAARCCNGTNATHATHACNGAYTCN GTNGAYGGNATGACNAAYGCNCCNTTYGAYTAYTCNYTNATHATHAARCAYGCNGGNAAY GCNACNGTNACNACNAARGARGCNGCNTGYGAYTCNYTNACNTGGGCNAARYTNGARAAY AARMGNGARACNACNGTNGCNGARYTNATHAARGGNATHCARGCNGGNTCNGTNAAYGAY TTYYTNTTYGAYTGGAGYYTNCCNYTNCAYTGYCCNAGYYTNGCNGARGARATHTCNYTN CCNYTNTAYTTYAARAAYAAYYTNYTNYTNCARACNGTNCCNGGNTCNYTNTAYMGNGAR AGYTGGCCNAGYYTNTTYATHGCNCCNAARGGNGCNAARACNGARYTNCAYGTNGAYGCN TTYAGYTCNCAYTTYTGGATGGCNYTNTTYCARGGNGARAARMGNTGGACNTTYTTYGAY AARMGNTAYACNGCNYTNYTNTAYCCNMGNYTNTTYCARTCNATGGAYCCNGTNTTYGAR GTNGAYYTNAAYCARCCNGAYYTNGARAARTTYCCNYTNYTNGCNYTNACNCARCCNCAR CARTGYATHYTNTGYCCNGGNGARYTNYTNTTYGTNCCNGCNGGNAGYCCNCAYTAYGTN GARAAYYTNACNTCNACNYTNGCNATHTCNTCNAAYTAYGTNGAYCAYACNAAYATHCAR AARGTNTGYGARGARYTNAARATHAAYGGNYTNCARGAYCARMGNGCNAARGAYYTNYTN YTNCARYTNCARGAYCCNGCNTTY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNACNYTNGGNCAYGCNGTNGCNAARTCNAARATHYTNTTYTCNMGNAAYMGN GGNGGNCARGARAARGGNGAYGAYAARAAYAARACNYTNMGNGAYGARTCNTTYGARTTY ATGMGNGGNGTNATGGAYGARTGYACNCAYYTNGGNAAYTTYTCNATHCCNGTNGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AARGCNCARYTNATHMGNGCNTCNAAYAGYCARAAY GTNMGNGARGGNGCNTTYTGYAARTAYAGYCAYMGNGAYTGYATGCARAAYTGYYTNGAR GGNTAYGAYTAYTGYGTNMGNCAYATHYTNGARGAYAARACNGCNCCNTAYMGNCARTGY GCNTAYATHACNAARGCNGGNMGNAARTGYCCNACNGCNGCNCCNAARCAYGARAARAAR GARGCNTAYTGYGCNTTYCAYACNAARAARGCNYTNGTNGCNMGNCARMGNYTNGCNMGN AARMGNMGNCCNMGNGARACNCCNGAYAGYYTNYTNGARGAYYTNGTNGTNACNACNTCN ACNATGGAYTCNCAYCAYAGYATHGARCAYMGNMGNGGNAARATHCAYAGYGAYAGYATH GCNTCNMGNGCNYTNGAYTAYGCNAGYTCNAGYGAYTCNGARGCNGARCCNYTNYTNGTN GARCAYGCNTGGMGNGAYTCNGGNGAYAGYGAYGCNGARAGYGTNGAYAGYGAYCARGAR GAYGTNYTNAARTAYGCNGGNGTNTAYACNACNGARGARGTNGCNCARATHYTNMGNGAY AARYTNATHMGNYTNCARGCNYTNTAYATHGAYCARTTYAARMGNYTNAARCAYATHYTN YTNACNAARMGNAARAARTAYYTNCARGCNCARAARATGGARMGNGARYTNTAYGGNAGY GTNAARMGNTAYAARGARGAYCCNCARCARMGNGARAARTAYGARAARYTNTGYGCNATG AARMGNTAYCAYAARAARTTYGGNGTNGARGCNYTNATGCARMGNCARTCNACNMGNMGN MGNATGAARATHACNGARGGNATGACNCAYAARYTNCCNACNCCNGTNAARTGYAGYTTY GTNGAYGARGGNYTNMGNTGYAAYCARTCNGTNGTNCCNYTNAGYAARTAYTGYCARAAR CAYATHYTNCAYGAYCARAAYCARGTNYTNTAYMGNCCNTGYCCNTTYGCNGAYAGYCAR TGYGGNMGNCCNGTNCCNTCNYTNYTNGGNAGYCCNTTYTGYTCNYTNCAYCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AAYATGACNYTNGARYTNTCNYTNCARATHAAYAARAARYTNCARGCNGTNYTNGARGAY ACNYTNYTNAARAAYATHACNYTNAARGARAAYYTNGAYACNYTNGGNGARGARATHGCN MGNYTNTCNCARGTNAAYMGNAARYTNCARYTNCAYYTNCARGAYYTNGARGARGCNAAR ACNGARGGNAAYGAYAGYTAYCARACNTTYATHYTNCAYGAYGARGAYCAYACNYTNGGN AAYGCNYTNAARTAYATHYTNAAYAARAGYCCNGAYGTNACNTTYGTNGGNTAYAGYATH ACNCAYCCNTCNGARAGYAARATHAAYYTNMGNATHCARACNTCNGGNAARCCNGCNYTN CARGTNYTNAARCARGGNYTNAARGAYYTNAARCARYTNTGYGGNCAYGCNYTNACNACN TTYGARTCNTCNACNAARTAYTAYMGNGARAAYCAYYTNCAYGTNTCNAGY---ATGGAY CAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNYTNGCNATGTGGGAYTTYGAYCAYTGYGAYCCNAARAAR TGYACNGGNAARAARYTNAGYMGNATGGGNTTYGTNAARACNYTNMGNYTNAAYCARMGN TTYGGNGGNYTNATHYTNTCNCCNGTNGGNACNAARTGYGTNGCNCCNGAYGAYMGNTCN ATHGTNGARATGAAYGGNATHGCNGTNATHGAYTGYAGYTGGGCNMGNYTNCARGARACN CCNTTYGCNMGNATGAARGGNGAYCARYTNMGNYTNYTNCCNTAYYTNATHGCNGCNAAY CCNATHAAYTAYGGNMGNCCNTGYAARYTNTCNTGYGCNGARGCNTTYGCNGCNACNYTN TTYATHACNGGNTTYTCNACNGARGCNGARAARATHYTNGARAARTTYAARTGGGGNCCN TCNTTYATHCCNYTNAAYAARGARYTNYTNGAYGTNTAYAGYGCNTGYCAYTCNAGYCAR GAYGTNGTNTCNGARCARAARMGNGTNYTNGARAGYTTYGARGARGAYMGNAARCARGAY AARYTNACNGAYTGGTTYTCNATGGAYCCNAAYATHGAYGTNTGYAAYCCNAAYMGNCCN ---------YTNTAYCCNCCNTCNGAYCCNTCNAGYTCNGAYGARGAYACNGARGARGAY AGYGARGCNGARGARGARGARAGYGAYGAYGAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TCNYTNTTY------------CCN YTNGCNGCNGTNYTNAAYTTYGGNTCNYTNGTNTAYATGYTNTTYTGGCARCCNACNCCN GGNTCNYTNATHCCNTAYTTYYTNATHATGGGNYTNTGGGGNACNACNGAYGGNATHTGG AAYACNCARACNAAYAGYYTNATGGGNATHATHTTYCCNGARAAYTAYGARGARGCNTAY GCNGGNYTNMGNATHACNCARGGNYTNAGYGTNGCNGCNGCNTTYGGNTAYTCNAAYGTN YTNTGYATGACNGCNAARATHTAYATHACNYTNGCNATGTGYGTNYTNGGNATHGTNGGN TAYYTNATHATGGARGGNATHCAYMGN---------------------------TGYGAY CARACNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGATG AARCARATHTCNCARCARCAYGCNGARGAYGAYGTNGCNTCNGTNTCNTCNATGGCNGAR GARGARATHCAYATHGGNCARYTNAAYGARGGNCARMGNGTNGAYTAYCARYTNCARGAR GGNCCNYTNGARAGYTTYAAYGAYTAYYTNTTYGCNATHACNTCNCAYTCNTGYTAYTGG GAYTCNGARGAYACNGCNYTNYTNGTNYTNAARGARATHTAYATGCCNGCNATGACNTCN CCNMGNCCNCCNAAYAARGARYTNGARMGNMGNCARAARYTNMGNGAYMGNAARMGNGTN CARMGNCARAAYCARGCNTTYGCNGARMGNGARMGNYTNMGNGCNMGNGGNMGNATHAAR GCNYTNMGNGARGAYCCNTCNTTYMGNCARGTNGARMGNMGNMGNGAYMGNGARMGNAAR MGNAARTCNMGNYTNGTNAAYYTNACNCARMGNATHCARGARACNGAYGGNGAYCARYTN CAYAAR------------CCNMGNCCNCARAARMGNGGNTAYGCNCAYATHAARTCNGAR TTYYTNYTNYTNGAYTAYAARCCNAARYTNCARACNGARTAYYTNAGYAARGARGTNMGN GARAARYTN------AAYGCNTCNAARGARGARGGNCARAGYAARGARGARGARYTNACN ---------------------------GARCCNCCNAAYAARAARCARAARATHAARGGN MGNAAYAARCAYMGNCCNMGNAAYGARMGNATHGARCARAARGAYAARYTNTGYCCNGCN ATHAARGARGARMGNGAYTGYAARTTYGGNGAYGGNTGYAARTTYAAYCAYGAYGTNAAR GAYTTYYTNGARAARAARATGGCNGAYATHGARAAYAARTGYCCNGTNTTYGARACNTGG GGNTAYTGYMGNTCNGGNGTNACNTGYMGNTTYGCNAGYGGNCAYYTNGGNGARAAYAAY GARAAYATHATHAAYAARGARYTNCAYGAYACNATGAARGARAARCCNMGNTGYYTNAAY ACNYTNAGYGAYGAYGCNMGNCAYAARYTNTGGAARMGNAARTAYGAYTTYAGYAARGCN ATGAAYTCNGTNAARAGYATG------------------GARAARAAYCCNCCNATHAAR GAYGAYGTNCCNGTNGTNATHGARAAR------------------------------GAR GTNGARAARAGYATHGAYTCNGTNGCNGAYACN------------------------ACN CARGARGTNGGNAAYAARGARYTNYTNTCNACNTCNAAYGAYAAYAGYCAYCCNACNACN GAY------------------------CCNGAYACNGTNACNGCNTCNAAYTGYGCNGAY ACNCCNACNGAYAARATHAAYGAYGAYGTNCCNACNMGNYTNACNTCNMGNGARGTNAAR AARATHGAYTTYAGYAAYAARYTNTAYYTNGCNCCNYTNACNACNGTNGGNAAYYTNCCN TTYMGNMGNGTNTGYAARACNTAYGGNGCNGAYATHACNTGYAGYGARATGGCNYTNGCN TCNCARYTNYTNAARGCNAARGCNTCNGARTGGTCNYTNATHAARMGNCAYCCNAGYGAR GAYATHTTYGGNGTNCARGTNTGYGGNGCNTAYCCNGAYATGATGACNAARTGYGCNCAR GTNYTNACNGARACNAGYGAYATHGAYTTYATHGAYATHAAYTGYGGNTGYCCNATHGAY YTNGTNTTYAARCARGGNAGYGGNAGYGCNYTNATGGGNAARGCNACNAARYTNGARCAR ATHTGYAARAGYATGATHGGNGTNATGGGNGARACNCCNYTNACNGTNAARYTNMGNACN GGNGTNTTYGAYCAYAARAAYGTNGCNCAYAAYATHATHCCNMGNYTNMGNAAYGCNGGN GTNTCNATGGTNGCNATHCAYGGNMGNTCNAARGARCARMGNTAYACNAARYTNGCNAAY TGGGAYTAYATHGAYCARTGYGCNGGNATHGGNAAYCCNATGCCNATHTAYGGNAAYGGN GAYGTNYTNACNTAYGARGAYGCNAAYYTNCAYATGGGNMGNAAYACNGTNTCNGGNGTN ATGATHGCNMGNGGNGCNYTNATHAARCCNTGGATHTTYACNGARATHAARGARCARMGN CAYTGGGAYATHTCNTCNTCNGARMGNTTYGAYATHYTNMGNTCNTTYACNAAYTAYGGN YTNGARCAYTGGGGNTCNGAYCAYCARGGNGTNGARACNACNMGNMGNTTYATGYTNGAR TGGYTNTCNTTYYTNCAYMGNTAYATHCCNYTNGGNGTNYTNGARCARGTNCCNCARAAR ATHAAYGARMGNCCNCCNTAYTAYATHGGNMGNAAYGAYYTNGARACNYTNATGGCNAGY ACNAAYTGYGCNGAYTGGATHAARATHAGYGARATGYTNYTNGGNCCNGTNCCNTCNAGY TTYCARTTYYTNCCNAARCAYAARGCNAAYGCNTAYCAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARGAYYTNYTNGCNGGN AARAAYGGNYTNYTNTTYACNTAYGGNATHACNGGNTCNGGNAARACNTAYACNATGACN GGNGTNCCNCARGAYCARGGNATHYTNCCNMGNTGYYTNGAYGTNYTNTTYAAYAGYATH GGNGAYAARCARGCNAARAARTAYGTNTTYMGNCCNGAYCAYATGAAYGGNTTYGAYGTN CARAGYGARGCNGAYGCNATGATGGARMGNCAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGARCARGARAAR GARACNTTYAARGARGARTTYCARGTNYTNATHCARGGNAAYAARGAYCAYAGYGAYCAR GTNTCNGARGTNMGNGAYTCNGCNTTYGARCAYATHTTYGARGARGARYTNAARGTNMGN CARAARYTNGARGCNGAYGAYAGYATHATHCARGARYTNAARGARTAYATHGARAARYTN MGNAGYGARMGNCARGARYTNAARGARAARATHGCNACNYTNAARTCNGAYAARAGYAAR TCNGARGCNYTNYTNGGN------------------------------------------ ------------TCNGTNCARCARGARAARGCNGCNTAYGARGARCARYTNGAYGGNAAR GCNGCNGAYYTNCARGGNAARGARGARAAYATHCARAARGARAARTCNAGYYTNCARAAY GCNYTNGCNAGYYTNGARACNGARAARTTYGAYAGYCARGARAARTAYTTYACNGCNTGY ATGGARGARATGAAR---------GCNGGNCARGAR---------------GCNGGNAAY GARMGNYTNGARYTNMGNGARATGAAYACNGARATGGAYMGN---YTNMGNGAYCARGTN AARGAYTCNGARGARYTNYTNAARGARAARGAYCARGARTTYGARGAYYTNAGYAARGAY AAYGTNATGTAYCARAAYGARATHGAYYTNGTNAARACNGARGTNTCNMGNYTNGAYGAR YTNTGYAARGGNAARGARATHAARYTNGARTCNGTNAARGARMGNATGYTNGARTCNGAY CARGCNYTNTGYGARATGGARGARACNATGACNGCNGCNCARMGNGARCAYGARAARGAR YTNAARAAYAARGARGAYGARYTNGARGTNTGGAARTCNGGNAARAARGARYTNGARACN MGNYTNGGNCARYTNCARGAYCARCARCARAAYGTNGGNGCNCARCARGGNATGGAYGAR CAYGAYGAYGARCARYTNYTNGARYTNCARAAYGARGARMGNGARACNMGNGARGCNACN ATHTCNCARYTNGARACNGARYTNTCNYTNTCNMGNGARAARATHGCNGGNYTNAARGAR GARYTNTCNCAYGCNCARGARACNATHGARTCNTAYAAYTCNAGYGTNGTNAAYGCNAAY AARAAYTCN---------------------------TTYTCNGARGARGCNTCNMGNCAR GARAARTTY------------------------GARGARAARGAYGARATGYTNAAYGCN YTNCAYGCNAARATGAAYTTYATHYTNCCNYTNYTNAAYTCNTCNCARATGGAYCARYTN MGNAAY------------------------------GARTAYAAYGAY------------ ---------------------------ACNYTNCCNTCNTCNAAYTCNGARTGYGARAGY AAYMGNAAYGARGARAGYGAYTTYATGGARMGNAAYCARAGYGARGAYGCNAAYGARTGY GAYMGNTTYATGGARYTNGARAARGARATGGARGARYTNMGNGGNAARYTNGGNGARAAR GAYGGNGTNGTNGTNGARYTNCARMGNTCNAAYTCNTCNYTNYTNGARYTNYTNGAR--- ---------AARAARGCNGAYYTNGGNAAYMGNYTNGCNACNCAYAARYTNGARGCNGAR YTNAARAAYYTNMGNGCNGARMGNGARCARATGGTNGCNGTNGTNAGYGARAARTCNMGN GARAAYTCNTCNYTNAARYTNGARATHCAYMGNYTNATGGAYYTNGTNTCNGCNGGNCAR ACNGCNYTNACNAARGCNCARCAYGAYAAYYTNAAYYTNGARCARMGNCARAGYACNCCN CCNMGNGAYGAY------GARGAYGAYGARATGAARMGNGARGCNYTNAAYAAYATGGCN MGNYTNGTNMGNGAYMGNGAYACNGARATHGARGCNYTNACNCARAARAAYACNACNYTN YTNGCNGTNYTNCARGAR---TCNAAYGARTCNGGNGCNGCNGCNCAYYTNGGNCCNYTN YTNAARGARAARGARACNYTNCARCARCARYTNGCNYTNATGGTNTCNGARMGNGARCAR YTNATHGCNTGYGTNCARCARAARCAYTCNGARTCNYTNGCNTTYCAYGGNGARATHCAR MGNYTNACNGCNYTNYTNGTNGARYTNCARGAYACNGCNGAYAARGCNAARGCNGARTAY TCNTCNYTNATHCCNGCNTTYGARGGNAARNNNCARGCNYTNYTNTCNACNCARAARGAR YTNGTNGAYTGYAARCARAARYTNACNGARYTNGARATHMGNCAYGGNGARYTNATHCAR AARTCNAAYAGYYTNCARAAYTCNTCNGAYTCNACNACNGGNGAYYTNGARGTN------ ------------------GARAARTAYAARMGNYTNGARTGYGAYTAYAARGCNATGGTN GTNGARMGNGAYGGNCARATHCARAGYYTNTCNCARAARGTNAARATGTCNGARGARGTN GCNTCNTCNAARGARTCNGARTGYATGCAYYTNAARAARCARYTNGAYAAYTCNAARTTY CARYTNACNGGNYTNATGGCNGARATHGCNGAYACNAARTCNGARMGNGARYTNGTNCAR CARAARAGYAAYACNCARAGYGARGARTCNACNAGYYTNMGNAAYAGYYTNAAYCARATG ACNYTNGCNGTNAARAAYAARGAYYTNGARATHGTNTCNYTNAARGAYCARYTNGCNACN YTNAAYTCNGTNYTNCARAAYCARAARGGNGARCARAAYCARGTNGCNCARYTNATHMGN GAYCARGARTCNTCNGTNGCNGCNACNMGNCAYYTNCARCARGARMGNGAYTAYAGYGCN ATGYTNGCNGARCARMGNYTNCAYGARTGYGAYGCNACNAARGCNGARYTNTCNGCNCAR AARGAYAARGTNTTYAARYTNGGNMGNGARYTNGARMGNYTNMGNAGYCAYYTNATHGAR ATHGARGARGGNTAYACNAARGARGCNYTNGARGCNGARGARMGNGARAARGARYTNMGN AAYAARYTNGCNGTNGCNGARGARCARYTNATGTCNTCNTCNTCNCARGTNCARGTNGCN AGYCARGARTCNCAYMGNCARATHGARAGYYTNCARGARCARYTNCAYCAYATHTCNAGY CARMGNGAYTCNGCNTAYATGCARGTNGCNACNACNCARGAYCARTGYCARCARTAYGCN GCNTCNYTNAGYAAYYTNCARYTNGTNYTNGARCAYTTYCARAARGARAARGAYTCNGCN ATHGCNATGGARACNGARAARTAYCAYGAYCARGCNAAYTCNYTNAGYGCNAARGTNAAR GAYYTNCARGCNGARYTNGARGCNACNMGNTCNGAYYTNACNGARGCNYTNGAYGGNYTN GARGCNGCNTCNMGNYTNAGYGARCARYTNGAYMGNAARGARGARGCNYTNYTNGCNYTN AARGARGARGTNCARYTNMGNGARCARGCNYTNAARGCNGCNGARGARGARATHTCNAAR YTNAAYTCNAGYACNGARGCNAARGTNGAYAARACNYTNATGCAYAAYATGGTNYTNACN TGGYTNACNTCNCCNGARAARAARMGNCAYGARATHGTNCARYTNATHGGNCAYGTNYTN GAYTTYAGYTCNGAYGAYTTYTCNAARATHGARTCNGCNCAYGGNCARGAYAGYYTNTGG ATHGGNTTYTTYAARMGNTCNTCNGGNAAR---CCNGCNAGYGARCCNAGYAARATGCAR TCNTCNTTYTCNCARYTNTTYGTNAARTTYYTNGARAARGARTCNTCNYTNCCNCCNACN CCNGTNAARYTNCCNGTNGARGCNATGGCNGCNGARGCNCARYTNMGNCAYAARACNACN TTYAAYCCNTTYATGGCNCCNMGNCAYGTNACNCAYGGNAAYGAYACNYTNGGNTCNTCN TCNAGYTCNTCNTCNCAYYTNYTNATHCCNCARGAYAAYYTNCAYCCNTCNCCNYTNTTY GCNCCNGTNACNAGYGTNTCNAGYTCNGGNGARAGYGCNATHYTNAARGAYGTNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNGGNAARGARGTNCAYTTYATHGAR AARATHGGNAAYGGNMGNTTYGGNGARGTNTGGMGNGGNAARTTYYTNGGNGAYGAYGTN GCNGTNAARACNTTYACNTCNYTNGARGARTGYAGYTGGMGNCARGARATGGARATHTAY ATHACNGGNATGYTNAGYCAYGARAAYATHYTNGTNTTYMGNGCNTCNGAYACNATHAGY MGNTTYTCNTGYACNCARAAYATHYTNATHGTNCARTAYCAYCCNAGYGGNTCNYTNTAY GAYTAYYTNCARMGNAGYGAYATHGAYATGGARGARATGYTNATHYTNGCNYTNTCNGCN GCNGCNGGNGTNAAYCAYYTNCAYTAYGARATHAARCARGGNACNGGNACNCAYGARAAR CCNTCNATHGCNCAYMGNGAYATHAARTCNAARAAYATHYTNGTNAARGCNAGYGGNGAR TGYTGYATHGGNGAYYTNGGNCAYGCNATHAARGAYACNAARGARTGGGAYMGNGGNMGN GGNMGNYTNTGGGTNGGNACNMGNMGNTAYATGGCNCCNGARYTNYTNTCNAARACNYTN AAYCCNGCNTAYTTYGARTCNTTYMGNTGYGCNGAYGTNTAYGCNTTYGGNYTNGTNYTN TGGGARATHGCNMGNMGNGCNMGNCCNTTYTGYGARGARTAYMGNGTNCCNTTYTGGGAY ATGGTNCCNGCNGAYCCNAGYYTNGARGARATGAGYGARGTNGTNGTNACNMGNAARCAR MGNCCNGCNATHCCNAAYAAYTGGGCNCARGARGARYTNATGYTNGARATHGARAARYTN ATHMGNGGNTGYTGGGCNCARCAYCCNCCNAAYMGNYTNAAYATHYTNMGNGTNAARAAR AAYYTN---CARGCNYTNMGNTCNCARACNGARCARATGATGGARAARMGNGTNAARYTN ACNGGNAARATHYTNGAYGGNAGYACNACN------------------------------ ATGYTNTTYAAYATGGAYGAYTGGAARCARGGNATGGAYYTNYTNTGYGARGAYYTNAAY ---------YTNTTYMGNAAYCAYTTYGAYTGYYTNTCNCARTTYGCNCCNMGNATHTCN ACNTGYATHYTNCAYMGNACNMGNACNTTYAARMGNGCNATHYTNGAYGCNGGNATGTCN CCNCAYAARAAYYTNCAYGAYATHACNTGYAAYTTYGCNGARAAYATHGTNAAYTGYYTN GARMGNCCNYTNTCNAARAARTGYCCNATHYTNGTNGTNGAYACNATGGTNGCNGCNYTN CAYMGNTTYYTNCCNCCNGCNTGYGCNCCNGTNCCNGCNGTNAAR---------ATGGGN AAY---------ACNAARCAYTTYCARCCNACNGTNYTNGARACNGTNATHGTNGARGGN GGNGGNGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CAYACNGGNATHATGTCNGTNCARGAYGARATHTGGMGNAARGARMGNATH AARAARGAYAAYCAYAAYATGATHGARMGNMGNMGNMGNTTYAAYATHAAYGAYMGNATH AARGARYTNGGNGGNYTNYTNCCNAARTCNATGGAYCCNGAYTCNMGNCARAAYAARGGN ACNATHYTNAARGCNTCNGTNGAYTAYATHGTNGCNYTNCARGAYGARCARMGNMGNTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGYTNCARGAYMGNATGGAYMGNYTNCARGAYGCNYTNAAYGCN TAYGGNCCNAAYTCNCARCAYTTYYTNAARGAYTCNGTNTTYAGYCCNTGGGARMGNGCN GTNGCNGTNAAYAARGTNCCNTAYTAYATHAAYCAYGAYACNGARACNACNCARTGGGAY CCNCCNCARYTNACNGTNYTNATGGAYTCNYTNATHAARYTNAAYAARGTNMGNTTYGCN GCNTAYMGNACNAGYATGAARYTNMGNATGYTNCARAARAARYTNTGYYTNGAYACNGTN TCNYTNCARATGGCNATGGARGCNTTYGAYAGYCAYGGNYTNMGNGGNMGNAAYGAYAAR YTNATGGAYGTNGGNGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARAARAARGGNAARGGNAARAARGARGAYGAYGAYTCNTCNCCNTCN------ ---------------------------AARCCNGCNAARGGNAARAARCARAARGTNTCN TCNACNGAYGARAAYACNGTNGARTCNGARGARGTNGCNGARAARACNAARAARGARAAR AAR------------GTNGCNTCNTTYGGNGTNGTNGAYTCNAARYTNYTNAARGARTCN GGNGAYAGYAAYACNAAYGAYACNCARAARCCNGARMGN--------------------- ------------------------------------------CCNAGYMGNATHAAYMGN GCNGTNGARTAYYTNCAYYTNTGGAARACNAGYMGNAARTCNTGGAARTTYAAYAARAAY TTYCARTCNYTNYTNATHAARGCNGCNTAYAAYTCNGTNATHATHACNGARGAYGAYTTY GARACNYTNYTNYTNTAYYTNGGNGARTGYAARGGNAAYGCNMGNGARAARYTNMGNACN GAYGCNATGGCNYTNATHAARGARGAYGARGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGGCNGCN CCN---ACNGARACNAAYTAYYTNCCNTGYGAYGAYTTYATGAARTTYCARGAYGCNYTN AARAARYTNMGNYTNATHGAYGAYMGNATHGTNCAYGCNYTNAAYMGNGGNATGCCNACN CARTCNTTYCARGGNAARGTNGAYACNTCNGCNAAYTGYMGNCARATHTAYGAYGAYATH CARATGTCNTAYGGNCARMGNGARAARTCNATHCARCAYTGYATHMGNYTNGTNGAYGAR GAYGTNAARGCNYTNAAYGARAARMGNMGNAAYGAYCCNGAYAAYYTNGAYGTNATGAAR AAYYTNMGNMGNGARCARACNAARYTNMGNYTNATGCARCARGARATGAGYGTNGARGAR GTNGTNAARGAYMGNACNYTNAARGTN--------------------------------- ---------------GTNTGYCAYYTNGCNGGNATGGTNMGNGGNCAYGGNCCNTTYTCN CAYYTNTTYGAYGGNAAYTTYATHCCNAARGTNAAYGGNAAR---GARTGGAARCAYGAR AARGCNTCNYTNGTNYTNGTNGARMGNATGYTNAARAAYAAY---------------GAY GCNYTNYTNGARAARTGYCAYYTNGARAAYGARGAYATHGARTTYATHAARGARYTNATH GAYGGNCCNAARGARGARGARGAYAARGTNTGGCCNTAYGTNGGNMGNTCNGARGAYAAR GCNTTYYTNTAYCARATHATHGCNAAYAARAARACNGGNATHGAYGTNGAYAARTGGGAY TAYYTNGCNMGNGAYTGYCAYCAYYTNGGNTAYGCNAAYAAYTTYGAYCAYAARMGNTAY GTNAAYTTYGTNMGNGTNYTNAARGTNGGNGAYMGNYTNGARATHTGYYTNMGNGAYAAR GARATHGGNAAYATHTAYCARATGTTYGTNATGMGNTAYAAYYTNTTYMGNACNGCNTAY CARCAYAARGTNGTNCARGCNGTNGARATGATGGTNGTNGAYGCNYTNGTNYTNGCNAAY GAYCAYYTNAARTTYCCNGGNGARAAYAAYMGNATGACNYTNTCNGARACNATHAAYGAY ATGAARGCNTAYGCNYTNACNACNGAYAAYATHYTNTGGATGATHTAYMGNTCNCARGAR AARGARYTNGARACNGCNAARAARATHGTNGARMGNATHTTYMGNMGNGAYYTNTAYMGN TGYYTNATHGAR------CAYCCNATGCCNAAYAGY------------GTNACNYTNATG GAYYTNACNACNGARATGATGAAYTCNGAY---------CARAGYYTNGAYAARGAYGAY TTYTTYYTNAARACNTTYAARATHGAYTTYGGNATGGGNGAYAARGAYCCNYTNAGYAAY YTNTGGTTYTAYTCNAARGCNTCNCCNGAYACNCCNACNAARGCNTCNACNGCNGGNYTN ATHATHCCNGARAARTTYAARTAYYTNGCNATHMGNGTNTTYAGYMGNAARAAYGAYGAR GTNGTNGAYAARMGNATHAARGARAGYTTYAARAAR------------------------ ---------AARCCNGTNAARCARGGNCCNCCNGCNATHGARCCNGCNGARGGNAAYTCN CCNGAYGAY------ACNAARAAYYTNGGNYTNCARTAYGARCAYTAYYTNAARGARGTN GTNGAYGTNYTNGARAGYGAYGCNGARTTYAARAARMGNYTNGARACNGCNAAYGTNACN GAYATHAARTCNGGNAARATHGCNATGTAYYTNGAYYTNGTNAAYCAYAAYGTNMGNGAY AARYTNCAYGARYTNAARMGNAARGARYTNGCNMGNYTNGCNCAYYTNGCNMGNYTNCAR YTNAARTCNCARACNGGNYTNAARAARTTYGAYATHCCNGAYCAYYTNGAYYTNGGNAAY CARCAYACNTTYGARATHAARGAYYTNGARAGYYTNATHAARAARACNACNTCNGAYYTN GARAARYTNGAYGARCARMGNMGNCAYGAYTTYAARGARTAYGARATGGARAARAARTTY GARMGNGARGARCAYATGAAYGARATGAAYGARGARGAYAARATHAARGARAARCAYMGN YTNGARGARYTNGARAARAARCAYAARGARCAYCCNAARATHAAYCAYCCNGGNAGYAAR GAYCARTTYGARGARGTNTGGGAYAARCARGAYCAYYTNCARGAYCARGARTTYGAYCCN MGNACNTTYTTYTTYACNCAYGAYCARAAYGGNGAYATGGARTGGAGYATHGAYGARGTN GAYTCNGTNYTNCARYTNGARYTNGAYAARGTNTAYGAYGCNMGNAAYTCNCCNGAYGAR GAYGAYCCNTTYGARMGNGAYGARGARATGAAYMGNATGMGNGARCAYATHTTYAGYGAR ATGGAYAARGAYAARAAYATGMGNATHTCNTAYAARGARTTYATHGAYTAYACNGGNCAR CAYGGNGAYAAYCCNGARTTYAARAARGAYGAYGGNTGGAARACNYTNGAYGARGARCCN GTNTTYGAYGAYGAYGAYTTYGARAAYTTYGTNMGNGARCAYCAYGCNCARCCNGGNGTN GTNAAYCCNCCNGAYCCNAAYYTNCAYTTYAARCCNGARCARCARYTNAAYCARCAYCAY CARCARCARCARCARTTYCAYCARCARCAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNGGNMGNAAYMGNAGYAAYMGNCCNGARYTN CCNTCNGCNACNAARYTNATHACNTGYCCNATHGTNAAYAAYGCNAAYGGNTCNTCNGGN ATHGGNAARAARAARGARTTYGTNYTNAAYCCNTCNGGNAARTCNTTYYTNTGYATHYTN CAYGARTAYATGCARMGNACNYTNAARATHCARCCNACNTAYGTNTTYAARGARYTNGAR AAYTCNAARACNCCNTAYGGNGCNACNGTNATGATHAAYAAYATHGARTAYGGNACNGGN TAYGCNTCNTCNAARAARATGGCNAARCARGARGCNGCNAARGARACNYTNAARATHYTN ATHCCNGAYYTNTCNACNAARATHACNGAYCARGARYTNAARAAYACNATHTCNGAYYTN TCNTTYTTYGAYGARATHCARGTNGARGAYCCNMGNGTNTAYGARYTNGGNAAYAARGTN GGNCARCCNAGYCCNTTYCARYTNYTNMGNGARTGYYTNMGNMGNAAYTTYGGNATGGGN GCNACNCARTGYGTNGTNAARACNACNGCNYTNAARAAYCARAARTGYGARTTYTCNATH CARGTNGGNAARCAYTCNGCNACNGTNGTNGCNAARAAYAARMGNGAYGGNAARCARYTN GCNGCNCARGCNATHYTNGCNAARYTNCAYCCNCAYGTNCCNAGYTGGGGNTCNYTNYTN MGNYTNTAYGCNACNAAYGTNGARAARCCNATGGAYAARGTNGARGARATGAAYGARATH AARACNCAYGTNCCNAAYAARGCNGTNYTNGARAAYYTNMGNGARGARATGMGNAARYTN CAYMGNCARAARGARGCNATHCARTCNAARGGNAARATGGTNATHTCNACNMGNGAYYTN CCNAGYAARATGTCNTGYGTNGAYYTNATGGTNGCNTTYGGNYTNCAYYTNGGNGCNTGY TCNGCNTGYYTNGCNGTNCAYMGNGAYGGNAARACNGARGTNATHGCNAAYGAYYTNGGN GAYMGNGTNACNCCNGCNGTNGTNGCNTTYACNGAYCARGAYATHTCNGTNGGNGCNGGN GCNAARCARGGNATHATHMGNAAYGGNGCNAAYACNGTNGCNCAYGTNAARCARATHATH GGNAGYGARATHGAYGAYGCNCARGTNAARGARTAYATHCARAAYCAYCARGTNACNATH GGNAAYCARAAYMGNTCNGTNGTNTTYAGYGTNGARCAYATGGGNAARAARGCNCARTAY AGYCCNAGYAARATHYTNGARYTNATHTAYCAYAARATGYTNGARACNGCNCARAGYCAY AGYGGNAGYGGNCCNAARGAYGCNGTNYTNGCNGTNCCNTCNGAYTTYACNCCNCARCAR MGNAAYYTNYTNAGYGAYGCNGCNACNAARGCNGGNTTYAARATHYTNMGNGTNATHAAY GARCCNTCNTCNGCNATGYTNGCNTTYGAYGCNGGNCARTTYGAYGAYACNGARCAR--- TTYAARACNYTNATHTAYMGNYTNGGNGGNACNTCNCAYGAYGCNACNYTNGTNAGYGTN GARCAYGGNATGTAYTGYATHYTNGCNMGNTCNACNGARAGYCARTTYGGNGCNGAYAAR YTNACNGARGTNYTNCARAAYTTYYTNGCNACNGARTTYAAYMGNCARTAYMGNTGYGAY GTNMGNGARAGYAARMGNTCNATGAGYAARYTNAARYTNGCNGCNGARMGNTGYAARCAY TCNYTNAGYTCNATGACNAAYGCNCARTGYAGYYTNGARTCNYTNTAYGARGGNATGGAY TTYTCNTAYAAYATGTCNMGNGCNMGNTTYGAYATGYTNTGYGCNCCNYTNYTNTCNCAR TGYACNCARYTNGTNCARCARYTNYTNGAYAARGCNGGNTGYAGYAARGAYGAYGTNACN AARGTNATHYTNTGYGGNGGNGGNGCNAARTCNCCNATHATGAARAARGTNATGACNGAY TTYYTNCCNACNTCNACNCARYTNAAYTCNATHCCNGARGAYGARATHATHGCNATHGGN GCNGCNAARGARGCNGCNYTNYTNGARGGNGAY---GARGARGARGTNAARATHCARGAR GARAARTCNACNACNTTYAARTCNYTNTCNAARGCNATHTGYYTNMGNGTNAAYTCNCCN GARYTNCARGTNATHYTNCCNCARCAYTGYYTNGTNCCNTCNMGNMGNCARCAYACNYTN ACNYTNCCNCARTCNCARACNAGYGTNGTNATHGARYTNYTNGARGCNGAYGARCCNGTN ACNTCNGAYGAR---ACNMGNTCNYTNGCNAARATHGTNYTNAARGGNYTNCCNCCNGGN TCNACNATHAARTCNAGYTTYCAYYTNACNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GARAARAGYYTNATGTCNCARAGYACNACNAGYAAYMGNYTNMGNCCN YTNCCNCCNMGNAAYCARAARCCNGCNAARAAYTTYMGNATHGGNAARCCNYTNCCNAAR TGGGGNGARACNYTNCCNCARGAYTTYTTYCAYMGNYTNCARYTNTGGGARGARGARMGN AARCARCAYAARCARGARYTNAAYGARAARACNYTNAARGAYATHAARGAYAAYYTNGAR AARAARYTNGCNGGNCARCAYAARYTNAGYAARCAYGARGARCARATHTAYGAYGCNYTN AARGAYGTNAGYYTNCCNGCNYTNTTYATGCCNTAYAARACNGGNAAYATHTAYAAYCCN MGNGCNCAYCAYTAYTTYCAYCCNACNGGNTCNACNGARGTNMGNYTNACNCARCCNCCN TCNGTNTTYACNYTNCCNCCNYTNCCNAAYAGYAARYTNTCNGTNGTNAAYYTNTTYGAR YTNAGYAARAAYTTYMGNAAYMGNGGNCCNGCNTGGYTNGCNGARMGNTAYATHCARCAR CARCARCCNTCNGARGARGAYTAYCCNCARACNCCNGCNCCNACNTCNGCNGTNCCNCAR GCNACNACNACNTCNGGNCARACNCCNATHAAYGARCAYGTNGGNTCNCCNACNAGYCAR MGNAGYATGCARCCNGARYTNGARGAYCCNMGNGAYCARAAYGCNGCNTCNAAYATHTTY TCNYTNACNAGYAARAGYGAYTGYGAYGAYAARYTNAARAAYATHTAYAAYTAYGARGCN GTNGTNMGNGGNTTYGAYCARAAYAAYYTNGGNACNGGNCCNAARACNTGYACNATHAAR ATHACNTCNCARGCNYTNTAYCARAGYGTNCARYTNCARATHCARATHACNTCNGTNGAY ATHAAYGAYTGYMGNACNCAYYTNTCNATHTAYGAYGGNCARGGNGTNCARAARYTNGCN ACNTTYGAYTGYCAYGGNGTNCARAAYATHAAYMGNATGAAYYTNGTNACNACNGGNGAY ACNGTNACNTTYATHATGAGYMGNGARAAYACNGAYAAYTAYGARTTYGAYATHGARATH MGNGTNAARCCNATHMGNGGNGGNTGGGAYCCNGAYCAYGARACNAAYTTY--------- TTYAAYTTYAARAARTTYGARCARGARGCNATHGTNGGNATGATHGGNGGNTTYTAYYTN YTNGTNYTNATHATHTGYTTYAGYGTNGTNTGYTAYTGYAAYGTNMGNTAYAARGGNYTN AAYAARAARTGGGARACNCAYCARYTNGCNACNATGAARACNGAYACNAGYTTYGARACN MGNAGYCARGTNTCNCARCCN------CCNTGGTCNGTNGGNCCNAGYCARMGNGGNGGN CCNACNAGYCARTAYTCNMGNTCNTAYGGNGARACNTAYTCNMGNAGYMGNCARCCNGCN MGNAGYGARGAYGGNTCNAGYGTNGTNTAYGAYCAYGAYGARAARTTYCARCARMGNAAY YTNATGAAYGARGARMGNGAYMGNCAYMGN---GGNMGNGAYMGNATGGCNTCNCARAAY ACNACNTAYACNGAYGAYGAYGAYCCNGAYAAYTTYAARGARAARGTNATHACNCCNMGN GTNMGNCCNGGNGGNMGNAARGAYMGNMGNCCNCCNTCNTTYGARGARGCNACNMGNGAR AGYTCNCARGARMGNTCNTCNTCNGARGARGARTCNGAYGARGARAGYGAYAAYGAYTCN GTNMGNAARMGNYTNACNACNTCN---------------------------TCNGARGGN GARAGYGARTCNGARACNGARTCNGARTCNGAYTAYAGYAAYGGNAGYTCNMGN---MGN GGNGCNMGNMGNGGNMGNGGNGCNAARGGNAAYAAYAARTCNAARGGNAARGGNAARCCN MGNAAR---------MGNMGNCARTCNGAYTCNGAYGAYGCNTCNTCNMGNCAYACNGAR CCNMGNAGYMGNCCNCCNCCNATHCARGGNGCNATGCCNTAYGGNGCNTAYCCN---CAR CCNGGNGGNCARTTYGTNCCNGTNATGGCNGGNCCNCCNCCNCARTTYCARCCNGTNCCN ATGGTNCAYCCNAAYTAYCCNCCNCCNCARTAYCCNACNGARGCNGCNTAYCCNCCNACN TCNGGNGTNAAYGTNAARCCNACNGAYCCNCCNGTNTAYTCNTAYYTNGTNMGNMGNGGN TAYACNCCNYTNGAYAARMGNAAYTCNCCNGCNGGNAGYGTNGCNTCNAAYCARMGNACN TCNCCN------MGNGARGARCCNGAYACNCCNYTNCARAGYGGNGTNGARTAYATGMGN MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GCNMGN CARTGYACNTGGTTYAARGCNAARGGNCAYATHAAYMGNTTYTTYATGACNTCNATHGAY CAYAGYATHTGGTTYCAYCAYCCNGTNATHGCNGCNGTNGTNACNCCNGTNCCNAGYAAR GARAAYMGNTTYAARMGNACNGCNGARGCNYTNCAYAARTCNGGNYTNTGGGARATHGCN ATGAARACNGGNAAYYTNATGAARMGNAAYCARGARYTNCARAARGAYYTNGARCARTTY AARATGGAYGCNYTNAAYTTYYTNAARTCNGTNATHAARAAYCCNGARAAYMGNGAYTTY ATHAARACNGTNYTNAAYAAYGCNYTNTCNGCNGGNGCNACNMGNAARAARAGYTCNGTN ATGACNGTNGTNGTNTCNGCNGCN------------------------------------ ---------------------ACNACNATHATGCCNATHAARGTNCCNYTNMGNGARAGY YTNACNAGYTCNYTNCCNCCNGARGARMGNTTYTCNCCNTCNATGYTNATHCARYTNYTN CARGAYAAYAARYTNACNYTNGGNGGNGTNGTNGAYYTNACNTAYACNACNAARTAYTAY GAYAGYACNTTYTTYGTNGARAAYGGNATHGAYTAYMGNAARGTNTTYACNGCNGGNCAY GTNATHCCNAAYAAYCARACNTAYAARCARTTYTCNAAYGCNATHAARGARGTNGARAAR GARGGNGARGTNACNTGYGTNCAYTGYACNCAYGGNYTNAAYMGNTCNGGNTAYYTNATH TGYMGNTAYYTNATHGARACNYTNAAYATHAARCCNCARAARGCNATHMGNATGTTYGAR GARGCNMGNGGNCAYAARATGGARMGNCARAAYTAYYTNGAYGAYYTNATGMGNMGNAAR CCNGGNGTNAGY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATHMGNGARGTNCAYYTNACNGAY GCNGGNYTNTAYACNTGYGTNGCNACNAAYGGNTTYGGNAGYACNAAYATHAAYTAYACN GTNATHGTNYTNGAYGARGARAAYAARGTNTTYCARGARGCNGAYAARYTNATHAARCAR TCNCCNAAYGARGAYATHTAYMGNGARGCNTCNGCNCCNATHTTYGARGARYTNAAYAAR ATGMGNGGNATGATGACNYTNATGMGNCCNAARGGNTCNACNYTNAARYTNGTNTGYAAR GTNACNGGNAAYCCNCARCCNCARGTNCARTGGTAYAARGAYTCNGARYTNTAYAAYCAR MGNMGNCCNCAYCCNACNYTNAARATHCAYGGNGTNACNGGNAARGAYAGYGGNMGNTAY ACNTGYGTNGCNAGYAAYMGNYTNGGNCARACNAAYTTYACNTAYAGYGTNCARGTNATH GAYGARATHCARGCNCCNAARYTNATHGCNCCNCAYCCNYTNAAYCARACNGCNTAYATH GGNGAYTCNGTNTCNTTYYTNTGYTAYATHGARAGYGTNGTNGARCCNGAYGTNAARTGG YTNAARMGNGTNGAYTTYGCNGAYAARATHTCNAAYCCNAAYATHACNYTNATHMGNTAY AARAARCARACNYTNATGGTNYTNAARGAYGCNGGNATHYTNCARGCNMGNMGNGAYGGN TCNTAYYTNAAYAARYTNGTNATHCARMGNGTNMGNCCNCARGAYGCNGGNAARTTYGTN TGYYTNGCNACNAAYMGNAARGGNTTYGTNAGYMGNCAYGCNTTYYTNAARGTNMGNAAR GTNYTNGAYYTNGTNGGNTCNTCNCARAAYCCNTCNTCNACNGAYTCNCARCAYTCNTCN CAYTCNTCNGAYGAYACNAAYYTNCCNYTNYTNATHGGNYTNCCNGCNTGYGCNYTNYTN ATHATHATHYTNATHGTNGTNTTYYTNYTNCARMGNAAYAAYMGNTGYMGNMGNTCNAGY ACNAAYAAYAARGTNCCNTGYACNCCNGTNCCNCCNGCNGARMGNGARGCNTAYTAYTAY AGYAAYTGYCARCARCAYCAYYTNCARCARTCNGTNAAYCCNYTNYTNATGTCNMGNGAR AARYTNCCNAARACNCCNACNCCNTCNGTNGAYATGACNGGNTCNGARTTYTCNTCNGTN TCNMGNACNCAYCAYCCNCAYCAYTAYCAYAAYAAYCAYAAYTAYGGNTAY--------- ---------------------AGYMGNAGYTCNAGYGGNAGYCCNACNCCNAGYGAYACN AGYTCNCARAAYGCNGCNATHAGYCARCARGCNYTNAAYGCNGCN---GTNATGAARAAY GARGARACNGCNAARYTNACNGCNTCNYTNAGYAAYTAYTAYAAYGARTCNYTNATHGGN CAYGTNYTNGGNTGGCARGCNGAYGCNYTNGARAARCARGCNTCNAARYTNTGGGARGAR ACNATGGTNAAYGGNAGYYTNCARTGYAGYCARATHTCNGTNGAYYTNAARAARGCNMGN TCNTTYGTNMGNATHGCNGARATHCARTCNACNYTNCAYGARCARMGNATHATGTCNTCN GAYCARCARMGNCARTCNATGTTYGTNACNGAYACNAARMGNTAYTAYGGNATHACNACN MGNYTNTGGGGNGGNGARAGYYTNAGYCAYYTNACNMGNMGNGARYTNGARYTNTAYMGN CARTTYTCNTCNGAYYTNCCNGTNGTNGCNACNGTNATGATHATHGCNTTYGCNCCNGGN GGNGTNTTYGTNTTYCCNYTNGCNTAYATGTTYCCNMGNTAYYTNYTNTCNCCNCAYTTY TGGACNAARAARCARMGNAARGAYTTYMGNCARYTNGARATGAGYAARMGNYTNACNCAY TAYCCNAGYGTNYTNGAYYTNATGCAYTCNGARTCNAGYAARMGNGARYTNCARATHAAR AARGCNGTNAAYAARYTNGARACNTCNTGGCAYYTNAGYMGNTCNATGGGNTTYTCNYTN MGNMGNAARAARYTNGTNAARGARGCNYTNYTNGTNCAYTTYATGGAYYTNGCNYTNATH MGNGARGGNATHCAYAAYYTNACNGAYGAYGAYYTNAAYMGNACNTGYCARTGGMGNGGN YTNAAYCCNGARGAYATGGAYMGNGARGCNAARYTNGCNTAYGTNAARAARTGGACNGAR ATHACNGCNGAYATHCAYGARCCNAGYATHACNYTNYTNYTNCAYYTNCCNATHYTNATG GCNTAYACNCARCCNTCNAAYMGNAARYTNATGGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGYTNGAYGARGARATHGGNGCNATGGAR AARAARGTNTCNACNMGN------CARGCNCCNGGNCARTGYMGNAAYGGNGGNGTNACN TGYGARMGNAARTCNGAYTTYACNCCNAAYMGNCAYGGNMGNGGNMGNMGNCCNTCNAAY ---------GGNGGNACNAARACNCARGAYACNCCNMGNCCNATHTCNACNCCN------ AARTGGGAYMGNTCNTTYGGNGAYAGYMGNCARMGNCARMGNATHTGYTAYGAYTAYMGN CARMGNGARGARGTNGARGARGCNGARGAYGTNTTYGAYGTNYTNAGYACNGGNTCNMGN AARGGNAAYGCNAAYCAYYTNYTNAAYTTYAARTTYTAYCCNMGNCARAGYCARTCN--- GAYGAYCAYMGNTGGTAYGAYMGNAGYMGNTTYAAYAAYCAYGGNMGNGGNGGNTAYMGN AARACNACNMGNTAYAARAARGARCARTTYYTNCARGCNAGYTGYCARTTYGTNGTNMGN GAYACNGGNGAYTAYACNGARCARGCNATHAAYTCNGAYGCNYTNGTNGAYTGGAAYATG ATHGARYTNGTNMGNAGYTTYTCNACNGARCCNGTNAAYTGYCCNATHTGYYTNCARATH CCNACNGCNGGNAARATHACNAARTGYGGNCAYACNTAYTGYTGGTCNTGYATHYTNCAY TAYYTNAARYTNGGNCARAAYGARGCNMGNAARTGYCCNATHTGYTAYGAYAAYGTNGAR GTNGAYGAYYTNAARAGYGTNCARTGGATHGAYGTNCCNGAYTTYAAYGTNGGNGAYGAR ATHACNATGMGNYTNATGMGNAARGCNAARGGNAGYGTNATHTCNATGCCNAARGAYCAR TGGGARGAYMGNCARGGNAARCCNATGAAY---ATHAARGGNACNAAYACNAARTAYATG AARYTNYTNGTNGCNTCNTGYGAYCARATHCARAARGAYGTNATHGAYATHGARMGNGTN GCNYTNACNGTNCARYTNGAYGAYGCNGARGARTCNGARGCNTGYTTYATHGARATGGCN YTNGARCAYYTNMGNGTNMGNGARGTNTTYYTNGARCCNGGNYTNTCNTCNAGYGARATH GAYAARGCNCAYGARAARYTNCARGARAARMGNGAYGCNAARCCNGARCCNCCNTCNACN GTN---------------------------------------TAYGCNGAYGCNTTYGAY GAYGARATHGTNGAR------------------------------------GAYTGYACN GARAAYAAYCCNGAYATHGCNGAY------------GARTCNCAYATHACNGARGARAGY GARACNGCNGCNACNGTNYTNGCNGARCCNTGYGTNGCN--------------------- ------------------------------------------------------------ ---GAYGAYGARTCNACNMGNCARMGNAAYGAYAGYGARTGYTCNYTNCCNTTYGGNTCN CCNCCNGTNCCNTTYCCNYTNGTNCCNGAYCARGARGTNAAYTCNGTNTCNYTNAGYYTN GARGARAARGCNGARMGNYTNGARYTNCCN------------ATGGAYATHCCNCARGCN GARAARCARCARCCNMGNAARACNMGNGAYACNTAYTAYTTYTAYCARGCNTCNACNGGN CARCAYATHTAYATGAAYTCNYTNAAYGCNCARTGYYTNTCNAARGARTAYGGNTCNYTN GARGARAGYCCNAAYAAYATHAARGCNACNATHGTNGCNATHGARMGNATHTTYATGACN GARGAYGTNMGNAARMGNYTNMGNTAYYTNGAYCAYATHCCNYTNACNTGYGARTTYCAY GTNGTNGARYTNAARYTNAARCCNCCNGTNATHAGYAARGARACNYTNAARTCNTTYGAR GTNGCNTTYGARAARAARMGNAARYTNMGNCARCARMGNGARMGNGARGAYAARMGNMGN GCNAARMGNTTYGARATGGARCARMGNAARAGYGAYGGNYTNTAYCCNGARATGCARATH CCNYTNGAYAAYATGAAYCARTTYCCNTCNTAYYTNTCNAGYAGY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GCNATHGARTAYMGNCCNATHAARACNYTNAAYGTNGAYYTNCCN TCNGGNACNAARATHYTNATHAARGGNTCNGTNYTNAGYMGNMGNCARGTNYTNYTNYTN CARGARGAYAAYGTNTGYGTNATGGGNGGNGARGTNGAYGAYYTNATHGTNGTNAAYAAY CCNYTNATGAAYYTNCARGCNGARYTNGARMGNAAYMGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYAAR ATHGTNYTNTAYGGNTAYTTYMGNAGYTCNGCNAGYTGGMGNGTNMGNATHGCNYTNGGN YTNAARAARYTNAARTAYGARCAYGARGGNGTNCAYYTNGTNAARGCNCARCARACNACN GAYGAYTAYAARAARATGAAYCCNATGGGNTTYGTNCCNACNATGAARATHGAYGGNYTN ACNYTNAAYCARTCNYTNCCNATHATGGARTAYYTNGARGARMGNAAYCCNGARCCNGCN ATHYTNCCNAARGAYATHGGNGGNMGNGCNAARGTNMGNGCNATHTCNGARGTNATHAAY AGYAGYATGCARCCNYTNCARAAYYTNAGYGTNYTNCARTAYGTNGGNGARACNAARATH GARTGGGCNAAYCAYTTYYTNACNAARGGNTTYGGNGCNYTNGARGARATGYTNAARGAR ACNTCNGGNTCNTAYTGYTAYGGNGAYCARGTNACNATGGCNGAYATHTGYYTNGTNCCN CARACN---GCNGCNGCNCCNMGNTTYAARGTNGAYATGTCNCCNTAYCCNACNATHAAY MGNATHGTNAARAAYYTNGARGARYTNCCNGCNTTYAARGARGCNGAYTTYMGNMGNCAR CCNGAYACNCCNGARGAYYTNMGNATHGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGTCNGAYAARYTNAAYACNMGNGTNATHCARGTNACNAAY ATHGCNCCNAGYTGYACNAARGAYCARYTNMGNACNYTNTTYGGNTAYYTNGGNMGNATH AARGARYTNGARATGTTYCCNCCNGAYGGNGCNGAR---GGNGTNGTNACNGCNMGNGTN GCNTAYATHGARTTYGARGAYTCNGTNACNACNGGNGTNGCNYTNCAYYTNAGYAGYACN GTNTTYATHGAYMGNGCNATHATGATHGTNCCNGTNATGGAYGGNAARATHCCNGAYGAR AGYTCNGCNYTNCARYTNACNCCNTCNGCNGTNGCNGGNATGYTNCCNGGNCARCCNACN TGGCCNGCNAAYGTNGTNTCNCARGTNACNGGNYTNGGNGCNAAYCARATHATHATGACN AAYGAYCCNMGNYTNACNTCNYTNGGNYTNCCNCARTAYCCNTCNYTNCCNGCNACNACN GAYCCNAGYAARATHGARGARATHMGNMGNACNGTNTAYATHTCNGAYYTNGAYATHAAR GTNACNCCNGARATGYTNYTNTCNTTYTTYTCNCARACNGGNGARATHAARTAYATHMGN ATGGCNGGNGAYGARAAYGGNCCNACNMGNAGYGCNTAYYTNGARTTYACNGAYCARMGN TGYATHGCNCARGCNYTNAGYTAYAAYAAYGTNGTNTTYCARGGNMGNACNGTNAGYGTN AARCAYGCNACNACNAGYATHGTNAARCCNACNCCNAARTCNGARGCNTCNCARMGNGAR ATHGAYGAYGCNATGAARAARGTNAARGARGCNTCNAARYTNATHTCNGCNGCNGCNAAY AGYGAYMGNGAYGGNTCNMGNTCNCCNACNMGNAAR------MGNTCNAARTCNMGNGGN MGNAGYMGNTCNMGNTCNAARTCNMGNMGNTCNMGNTCNMGNTCNMGN---GGNMGNMGN MGNMGNAGYMGNTCNMGNTCNMGNMGNMGNTCNMGNTCNMGNMGNMGNTCNCCNMGNMGN TCNMGNACNCCNGTNMGNMGNMGNMGNTCNMGNTCNMGNGGNMGNGTNCCNCCNCCNGCN CCNCCNGTN------------TCNMGNGARMGNMGNMGNTCNMGNACNMGNTCNCCNGTN MGNMGNMGNMGNTCNMGNTCNMGNTCNAARTCNMGNACNMGNMGNTCNMGNACNCCNCCN AARTCNTAYAGYMGNMGNGARGGNTCN--------------------------------- ------------------------------------------------------------ ------GCNGCNAAYGGNGAYGAYMGNGAYGGNTCNATHAARGGNGGN------GCNMGN TCNCARAGYCCNGCNAARGCNMGNAARMGNAGYYTNACNCCNAARAARMGNAGYGGNTCN AARTCNCCNAGYMGNMGN---AARAARMGNMGNCAYTCNMGNTCNACNTCNMGNAARMGN TCNTCNMGNTCNMGNAGYGGNTCNMGNCAYMGNTCNMGNAARGAYMGNAARMGNAGYMGN AGYMGNGAYMGNAARCAYGARAGYAGYAARAARAARAGYGGNMGNGAYAARGARGAYAAR AARAARGARAGYGGNAGYTCNTCNAARATHAARMGNGAYTAYGAYGARGARGARAARGGN TTYGCNAGYGARGGNAGYGARGARMGNGAYAAYAGYGARGGNGGNGGNTCNGTNGAYTCN TCNGGNGARYTNCCNCCNGTN------YTNGARAARGAYACNGAYCAYCARACNGTNGAY ATGGAYATGAGYGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CCNYTNACNGAYYTNGARAARGARATHATHGCNTGYYTNMGNGTNGGNGGNGAYAARTAY GGNAARAARATGGAYGAYCARYTNGAYGCNYTNAARTCNGCNGTNTCNGARGARGCNTAY ACNMGNTTYMGNAGYACNGTNCARAAYTCNATGGGNCARGARYTNAGYTGGAAYACNGTN GCNYTNYTNTTYTAYGCNACNAARGGNGTNGTNTCNGCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------MGNGCN GARYTNGAYAAYGGNCARGGNAARYTNYTNGAYTAYTGYYTNCARATHGCNAGYGGNATG GARTAYATGAAYTGYMGNAAYATHTTYCAYMGNGAYYTNTCNGCNMGNAAYTGYYTNGTN GGNAARGAYGARGTNGTNAARGTNGCNGAYTTYGGNYTNGCNMGNATHGTNYTNACNGAY AGYGARTAYCAYATGTCNGARMGNTCNAARTTYCCNTTYAARTGGTCNCCNCCNGARGTN YTNCAYTAYMGNAARTAYTAYAAYAARTCNGAYGTNTGGTCNTAYGGNATHYTNATGTGG GARGTNTAYTCNTTYGGNCARYTNCCNTAYCARGGNYTNAARAAYCCNGARGTNACNAAR TTYGTNGTNGTNGAYAGYAARMGNYTNAGYAARCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CARAGYGGNTTYGGNGCNCCNGCNCCNAGYACNGCNCCNACNGGNTTYGAYTTYGGNCAR GCNGCNCARCCNGCNACNAGYCCNGCNGGNGGNTTYAAYTTYTCNGCNCARACNCCNACN CCNGCNCCNGCNGGNGGNTTYAAYTTYAAYGCNGGNGCNGGNACN------CCNTCNTTY AAYTTYAGYGCNACNCCNACNACNCCNAAYATGTTYACNCCNCARACNCCNGGNTCNGTN CAYMGNCCNMGNGCNGCNGCNMGNMGNCCNACNMGNMGN---------CARATHTCNCAY ATGATHGCNTTYATHGAYCARGARGCNTCNGARAARGTNGARGARATHGAYYTNAARGCN GARGARGARTTYAAYATHGARAARGGNMGNYTNGTNCARCARTCNMGNGTNCARATHATH GAYTAYTAYGAYAARAARGTNAARAAYGTNGARYTNCARAARAARATHCARAAYTCNAAY ATGCARAAYAAYGCNMGNYTNGARATHYTNMGNMGNAARGARGARTAYGTNAARGARGTN YTNGAYGARGCNMGNGARCARYTNMGNAARGTNGCNAARGARAAYCCNGARGARTAYAAR MGNYTNCARAARAARYTNATHATGCARGCNYTNGCNMGNATGATHGARGCNAARGTNTCN ATHMGNTGYMGNMGNGARGAYGTNCARATGATHAARAGYGCNATHCCNACNYTNGARCAR GARTAYAARCARYTNYTNAARGGNAARTAYTCNGTNCARYTNGTNGTNGAYGARGARAAR TTYYTNTCNTCNGARATHTGYGGNGGNGTNGARYTNMGNGCNATGAARGGNAARATHGTN GTNGTNAAYACNYTNGAYGARMGN---AGYGARTCNGTNACNGGNGCNTAYGTNYTNTGY YTNYTNCAYCARCAYMGNGTNCAYCARTAYMGNATHYTNCCNGAYAARGAYGGNAARATH TCNGTNCARTCNGARGGNGAYATGCARCCNCCNTCNTAYAAYGAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATHTAYGAYGCN---AAYCARCCNYTNACNYTN ACNGTNAGYAAYGTNAAYCARGGNACNGARGARGCNCARGCNGTNCARAGYATHCARTAY ATHTCNTCNGAYGGNGTNCCNGTNACNCARYTNGAYTCNAAYGAYGTNATHCARGTNGCN CARGCNGCNGAYGGNACNTTYCARCARACNACNACNGGNTAYCARAAYYTNCARGCNGCN GTNCARCCNCARGTNATHACNAAYGCNGCN------------TCNGTNACNTCNCARCAR GGNGGNACNATHYTNCARTCNAAYAAYGTNYTNMGNAAYGTNGCNYTNCAR------ACN CCNCARGTNACNCARCARACNCARCARGCNATHCARACNGGNACNTCNAGYACNGCNGTN GGNACNGCNGGNATHCCNCARATGYTNTTYYTNAAYCAYGTNACNATHAAYGGNCARACN TCNYTNGTNYTNGTNGAYGCNAAYAAYAARCCNATHCARYTNCCNCARGGNATHCARGTN ATHAAYYTNCCNCAYCAYCARTCNGGNGGNCARTCNATHCARATGCCNGGNAGYGAYACN GGNGAYGARCCNYTNTAYGTNAAYGCNAARCARTAYCAYMGNATHYTNAARMGNMGNCAR GCNMGNGCNAARYTNGARTCNGARGGNAARATHCCNAARGARMGNMGNAARTAYYTNTAY GARTCNMGNCAYMGNCAYGCNYTNAAYMGNGCNMGNGGNACNGGNGGNATHTTYGTNGGN CAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AGYYTNTCNTCNYTNGGN ATGAARAAYGGNGAYMGNATHATGGTNTTYGGNAARATHTCNAARGAYGTNAARGARAGY GGNGAYGAYAARGTNATGGAYGGNYTNATG------AARGTNYTNGAYCARCAYCARGCN AARATHGARGARATGTGYGARYTNTGYAARGARATGGTNAAYAARATGGGNCARACNAAR GGNACNGTNGAYGAYTGGAARAARCAYAARAARTTYTTYATGTGYCARTCNGARTAYTGY ATGCARGARYTNACNMGNYTNGAYGCNACNCCNGCN------TCNCARTGYCCNAARTAY AARACNMGNMGNAARACNYTNGTNAAYMGNYTNYTNGARAAYATHGCNATGTGYGAYAAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNACNAARGAYATHATH CCNGAYGARCARGARATHAARGCNAARATGGGNAARAARCAYAARTAYGGNAARCAYTCN TCNAGYAGYTCNTCNAGYAGYAGYAGYAGYGAYTCNTCNGAYGAYGAYTGGAARCAYYTN CCNAARCAYGARAARAARATGMGNAARAARTGGAARAARCARAARMGNAARGGNATGATH GGNCAYACNGCNYTNCCNCCNTGGCARGGNGGNCCNGCNTGGGCNCCNCCNATGAARGCN GGNAARAARGGNCAYAARGGNAARGGN------CAYGGNGCNGGNCAYCCNCCNCCNGTN GGNTAYCCNGGNCARCCNGGNTAYCCNGCNCAYCARCCNGGNTAYCCNCCNGGNTAYCCN CCNCARCARCCNGGNTAYCCNGGNCARCARCCNGGNTAYCCNGGNCARCARCCNGGN--- TAYCCNGGNGGNGGNTAYCCNCARCCNGGNTAYCCNCCNCARGGNGCNTAY---CCNGGN GGNCCNCCNCCNGGNGGNTAYCCNGCNGGNAGYCAYCCNCCN------------------ ------CCNCCNGCNGCNCARTAYGCNCCNCCNGGNGGNGCN---TAYGGNTCNTAYGGN GCNCCNTCNGGNCCNTTYCARGCNCCNCCNGGNAGYAAYCAY------CCN------GGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CARAARGARATGACNGARAARGARYTN AARGARGARATHMGNGCNMGNATHTCNGCNGARGARMGNYTNAARGARGCNGARCARTCN YTNAAYTGYYTNGAYCAYGCNGTNCARACNCARTCNCAYMGNATHGARGARGGNGCNAAR GARGARATGAAYGTNAGYGTNMGNAARYTNAARCAYTTYTTYGARGAYYTNGCNGARGAR GCNAARATGTCNTCNGAYAARCCNATHGTNATHMGNAAYGGNYTNATGGCNMGNAARACN YTNGCNMGNMGNGCNAARACNGTNMGNTAYCARAAYMGNMGNMGNGARTCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TCNACNYTNGCNAAYYTNCCNACNCCNAARCCNGGNTAYGGNCCNTCNTAYATGGCN CCNMGNGCNGCNACNYTNCCNYTNTCNGGNGCNTAYGGNGCNMGNGAYGAYTTYMGNTTY TAYGARTTYGAYGARTCNGAYGAYMGNCCNAAYACNAAYYTNTCNTCNTCNACNYTNACN GGNCAYAGYACNTCNACNMGNCAYGAYTCNTCNTAYAGYGGNTAYGARGGNCCNAAYATH TCNYTNYTNAARYTNCARAARAGYACNTGGCAYACNGARATHGARCCNACNATHTAYGAY TAYGARMGNYTNAARATHACNAAYTTYGAYYTNCCNAARGAYGTNGAYATHAAYCAYYTN GARATHCAYYTNACNAAYGARGAYTTYGAYGARYTNTTYAARATGCCNAARGARMGNTTY TAYMGNATGGCNGARTGGAARMGNAAYGAYGTNAARMGNAARYTNAAYYTNTAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHAARGTNYTNGARTTYATHYTNGCNATHTTYGCNTTYGCN ACNACNACNAGYCCNGARACNTCNACNACNTTYACNGTNAARAAYTGYAGYCARTGGACN AAYCAYACNGTNACNGCNTCNGCNTCNMGNACNTAYACNTAYAGYTAYCCNTAYGAYYTN GARAAYGTNTGYTTYGAYYTNCCNGTNTGYAAYTTYYTN---GTNAAR---------AGY MGNTTYTGYYTNYTNGARGGNTCNCARTCNGCNGCNCARTTYTAYGTNTTYGTNGGNGTN ATHGTNTTYYTNTAYTGYYTNGGNGCNYTNGTNGTNTAYGTNTTYTTYGAYGARGTNTAY MGNMGNAAYACNMGNTTYGTNGTNGCNGAYTTYGTNATHTCNTGYGTNYTNACNYTNTTY TGGATHATHTCNTCNTCNGCNTGGGCNGCNGGNYTNTCNGAYGTNAARYTNTAYACNGAY CCNGCNGAYGGNGGNATHATG---CAYAAYGTNCCNGARTGY---TTYGCNAARGGNGCN TGYTCNACNTCNAARGARGGNAAYTTYGCNAGYYTNAAYGTNTCNATHATHTTYGGNTTY YTNAAYTTYATHGTNTGGATHGGNAAYYTNTGGTTYYTNTAYAARGARACNCCNTGGTTY AARGTNCARGCNAARCCNCCNACNCARCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARYTNAAYGTNAAYYTNCAYCAYTGGGAYYTNGAYMGNTCN YTNYTNAAYAAYYTNCARGARGTNYTNGARATHGAYTTYCCNACNCCNTCNGAYACNAAR AARGARGARYTNAGYGTNGAYTGYGGNATHTGYTAYAGYCAYCARYTNGARGAYGARATH CCNGAYATHGTNTGYCARCAYCCNCARTGYAGYCARGCNTTYCAYTAYACNTGYYTNTAY GARTGGYTNMGNAAYTCNTCNTGYMGNCARAGYTTYAAYTAYATHTTYGGNGARTGYCCN TTYTGYAGYAARCCNYTNMGNGTNAARATHATHAAYACNCARCCNCCNCCNCCNCCNCCN CCNCCNCCNCCNCCNCCNYTNGCNCCNAARYTNGGNGAYGARAAYAGYATGGAYATHGCN TCNGAYGGNGARGAYGAYCAYGCNGTNGGNGGNGARMGNTCNCAYCCNCARAAYATGTGG ATGCARCAYCARCARCARCARCAR---TGGTGGCCNGCNGGN------CARATGTGGATG CARCARCARATGTAYCCNTCNAAYCARAGYTTYGGNAAYGGNAGYGAYAAYGGNGGNCCN CCNTTYCCNCCNAAYCARGAYMGNCCNAARAARGGNGARTCNTTYAAYCCNTAYTGGGAR GAY---CCNGARCARGAYAGYGAYAGYMGNMGNCAYCAYCCNYTNYTNGGNGTNAARCCN CAYCAYTCNGAYCAYCAYCAYCAYMGNCAYCAYTCNCCNCAYAGYGAYCARCAYCAYCAY MGNCAYGAYMGNATGGGNGAYGGNTAYGGNTCNGGNATGGGNGCNTCNTCNTAYGARTCN GGNYTNGAYGCNGCNAARMGNMGNACNYTNCCNYTNTGGYTNMGNGARGGNYTNGARAAR ATGGARMGNGARAARCAYAARYTNYTNGARAARGARCARATGAAR---CARAARCARAAR GARATGYTNGCNATGCARGARGARTCNACNAARMGNMGNGAYGAYGTNGARGAR------ ------------AARGAYCCNMGNAARAGYMGNTTYGARTCNGAYGAYGARGAYGARGTN TCNGAYAARAARGGNGARGARGAYGAYGARGTNGGNGGNAAYGARGCNGAYCAR------ ------------GTNGTNGARTCNCARTCNCARGARAARGGNCCNAARYTNTCNCCNAAR MGNAGYCCNTCNCCNACNGARTTYATGACNGARGARGARAARGARYTNGCNYTNATGATG AARGTNAARMGNYTNYTNACNGARACNYTNYTNGCNGTNACNGAYCARGARATGMGNAGY ATHGCNTCNGARGTNTAYCARMGNGARAARAARAARGCNYTNAARGCNCCNGCNAARCAR YTNGCNAARTCNTCNGCNYTNGCNTCNYTNTCNACNYTNGGNYTNGGNTAYGGNTCNAAY AGYGAR---AGYGAYAGYGARGCNMGN---GARAARGAYGARGAYTCNGAYAGYGAYYTN GARGARMGNATHMGNAARAARAARGCNGAYTTYGCNAARMGNCARAARATHTTYAGYGAY GCNGARGAYAGYGAY---------GAYGAYAARGCNACNTCNCCNGTNAARAARTCNGGN GGNGARMGNAGYMGNGAYGTN------AARYTNGAYGTNCAYTCNGGNAARGAYAGYAGY GARAARYTNGAYMGNMGNCARGGNGAYMGNMGNGAYTCNGAYMGNAGYGTNAARTCNGAY MGNTGYGAYAGYAARGAYGAYATHGTNAARAARGARAGYCARGGNAGYMGNTGGGAYTCN MGNTCNAARCCNGAYATHGCNACNGAYAARGGNAARCAYACNGAY--------------- ------------AARGTNGARAARGGNGCNAARCARGAYAARYTNTCNGGNGTNAARGAY ATHATHCCNAARTCNGAYGARAARAAYAARTCNAARGCNGTNAARAARAARGARGAYACN AGYGGNAGYAGYAGYGGNAGY------------------AGYAGYGGNTCNTCNAGYTCN GAYTCNGARGAYAGYAGYAGYGGNAGYGAYGGNAGYTCNTCNTCNTCNTCNTCNTCNTCN TCNTAYATHGAYCCNAARTCNAARGCNAARATGAARTCNAGYGTNCARAAYAAYGTNAAR ATHGCNGARAARGCNGARAARATHAARGAYGCNGAYAARGARAARCAYAARAGYAAYGAR GARAARGAYMGNAARGCNTCNAARACNGARAARGAYAARAARGGNGAYGCNAARGTNTCN AARTCNGGNMGNAGYGARGARGCNMGNTCNCCNMGNAARGCNAARGCNGARGAYACNAGY AARCAYAARGARAARTCNAARAARAAYAGYAARGAYAARMGNAARMGNAGYAGYTGGGAY GGNGARAAYGARAARAARYTNAARAGYAGYAARACNTCNMGNAAYMGNAGYMGN------ ---------AGYMGNGAYTAYGARGAYAGYMGNCAYMGNGARTAYAGYGARGARMGNGGN MGNAGYMGNAGYGAYTCNMGNGAYTCNAARAGYAARAGYAARMGNCAYMGNAGYMGNAGY AAY------------TCNMGNGAYGTNMGNGARMGNMGNMGNGARMGNAGYMGNAGYGAY TCNMGNYTNMGNAGYMGNAGYCAYTCNCAYGARAAYTTYMGNGARAARGAYTCNYTNGAR GAYTCNMGNGAYMGNAGYCAYCAYMGNGAYYTNAARTAYAGYGARGARGARMGNGAYMGN ---CARACNMGNCAYAGYMGNGARMGNMGNGAYAGYTTYMGNAGYACNAGYMGNGARATG MGNMGNAGYMGNAGYACNGAYAARMGNMGNGAYMGNACNMGNAARMGNAGYMGNAGYACN GARAARGTNTCNTCNATHMGNGARMGNCCNTCNMGNAARTCNGGNAARAARMGNAARMGN GCNMGNTCNTCNTCNGARAGYGARGGNTCNMGNAARCARAARAARAARAARTCNAARTCN TAYGGNGARGARMGNGARAARGARGGNGARAARGARTAYMGNAARGAYGGNAARACNGCN MGNAAYAARMGNGGNMGNTCNMGNTCNMGNTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARGTNAARYTNGTNYTNAAYGCNGCNMGNACNTCN TTYACNAARTAYATHGAYMGNYTNTCNYTNTTYTTYCCNACNTCNTCNYTNCCNGTNCAY TCNTCNGTNMGNGARMGNTCNTCNYTNYTNMGNAARYTNGARMGNCCNYTNTGYCAYYTN YTNMGNAAYYTNTCNCCNTAYTCNAARGGNAGYYTNATHTCNTCNCARGARGTNATGAGY AGYYTNCARAAYCAYATHYTNGAYYTNACNCARMGNYTNCAYGCNGCNGARAARGARMGN MGNCAYYTNYTNGCNGAYYTNAAYGAYYTNAARCARCARATHGGNGAYGARAAYATGCAR GTNCARAAYTCNGTNGAYAARCAYGCNTCNGGNAARGGNACNAARTAYGTNGCNATGGAY AARTTYGARAARGTNTGYGTNGARYTNTCNGGNGCNYTNMGNMGNGARCARAARGCNCAR GCNYTNYTNCARGARCARAGYAAYCARYTNACNGARYTNACNTCNMGNYTNGAYATGTGY GCNTCNGAYGGNGTNCAYAARGARAARAGYYTNGTNCARTTYCARGARGGNYTNTCNGAR ATGCARGGNGARYTNMGNCAYAARGAYCARAAYYTNMGNCARATHGGNAARCARYTNGGN CAYATHGARTAYGARMGNGAYTCNYTNCARAGYAAYYTNAARGAYGCNGARAGYGCNYTN MGNACNGCNGCNMGNGAYAARGARATHYTNGCNCARTAYATHAARAAYGTNGGNAGYGCN YTNGARTCNGCNAARAARCARTTYYTNATHATHAGYGARCCNCCNCCNYTNTCNAARGAY GTNTCNYTNTCNMGNYTNYTNYTNGAYGCNGAYYTNATHCCNYTNGAYATHGGNAARACN GGNCCNGARYTNATHTCNYTNCARAAYYTNGTNGGNGGNTTYGTNGAYGCNCARCAYCAR GCNGTNAAYAARATHMGNTCNYTNGARGARGARATHGCNTCNCAYMGNAGYCAYATHGAR TCNYTNAARAARGARYTNAGYAAYGCNGTNCARMGNGARTTYAAYCARCARYTNGARTCN GCNACNGAYGGNGCNTTYTCNGTNYTNACNGAYCARGARGARGAYYTNGTNCARYTNAAR AAYGAYTCNGAYGTNTCNTAYGARAGYYTNCCNACNYTNMGNAARYTNACNCCNCCNATH TCNACNAGYYTNAAYCAYCCNTCNYTNCARCAYAARAARTCNGCNTTYCAYTCNGTNAAR TCNAGYAGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARYTNGCNTCNGCNACNAAR CAYGARACNYTNTCNAARAGYCAYMGNYTNGCNGCNGTNATHCCNYTNAARTTYAGYTTY CCNTTYTAYGGNCAYCCNGTNACNAAYGTNACNGTNGCNACNGGNGGNTTYATHTAYATG AGYCCNTTYYTNCAYCARTGGYTNACNGCNACNCARTAYATHGCNCCNYTNATGGCNAAY TTYGAYCCNTCNTCNACNAGYTCNTCNAAYATHTAYTAYYTNAGYGARGARGAYACNTTY ACNGTNGARTGGAARAAYGTNATHYTNCARGAYCARCCNYTNYTNGGNAGYTTYACNTTY CARACNTCNYTNTAYATHAAYGGNAGYGTNAGYTTYGTNTAYAARGAYATHCCNGARAGY ATHAGYAARATHTCNGAYMGNAAYCAYCCNGTNAARATHGGNYTNTCNGAYGCNTAYTAY AAYGAYACN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNACNTGGTAYATHGAYGARYTNACNMGNATHYTNGTNAARTAYCAY GARMGNGARAGYYTNCARCAYATGYTNGTNYTNGTNAAYCARTCNGTNACNAARAAYMGN TAYCCNCAYACNAAYGAYCARGGNGCNATGGARCAYTAYACNCARGTNCCNGCNCCNCAR CAYACNYTNACN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNGCNCARACNGGNGCNYTNYTNAGYGTNAARGAYGCNTCNGAYACNAGYTAYATG YTNTCNYTNMGNGARATGCAYACNCARATHTAYGARYTNACNGAYAARYTNMGNGCNGAR AARCARGARACNCAYGTNYTNTCNMGNAARGCNCARGAYATHYTNATHAARCAYAAYTCN YTNCARAARGCNYTNTCNGAYGTNGARMGNATGTCNAGYAARGARAARGCNMGNATHGCN GGNMGNAARGARGARACNGTNAARYTNAARACNAAYATGGAYGARAAYAARAAYAARATH GCNAGYYTNCARATGGARATHGCNAARACNGGNGTNAGYGARGCNGAYTTYCAYGAYAAR YTNTCNAARAARMGNGARMGNYTNGARGGNYTNGARAAYGARYTNGGNCCNYTNAARTCN GARYTNCARTCNTAYTCNAGYYTNCCNCCNGAYGCNGTNGARGCNAARYTNAARATHGAR CARYTNTCNMGNGARYTNAARMGNMGNGARACNGARATGTCNGCNTGYATHGAY------ ---------------------------AGYTGYYTNYTNGTNGTNYTNACNGTNGCNATH TCNTCNACNGCNGGNYTNGTN---------CAYGGNAGYTGYCCNAGYCCNGGNAGYCAR GAYGAYTTYGAYYTNAGYCARTAYYTNGGNAARTGGTAYGARTAYGARMGNTTYAAYGCN TGGTTYGARYTNGGNGTNGTNTGYGGNAGYGCNGARTAYGCNYTNAAYGAYGAYGGNAGY ATHAARGTNGTNAAYGGNGGNCAYMGNAAYATH---------------GCNGGNTTYAAR TTYCCNACNTCNGTNACNGGNAARGCNACNGTNCCNGAYGARTCNAARCCNGGNGARYTN MGNGTNTCNTTYTCNMGNTTYGAY---CCNGGNACNGGNCCNGCNAAYTAYTTYGTNGTN AARACNGAYCAYACNAGYTAYTCNGTNGTNTTYTCNTGYACNAAYYTNCCN---YTNGGN TTYAGYYTNCARTAYGCNTGGATHYTNACNMGNGARMGNGGNGTNGCNCCNACNGARYTN GCNTCNATHAARTCNTTYYTNCARGAYGGNGGNATHGAYYTNAGYCAYTTYAARTCNGTN GAYCARTCNGAYTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARGCNGCNCARACNCARTAYATHGARCARYTNGARMGNTAYGARAAYAAYCAY YTNGGNAAYTTYMGNMGNATHTTYCCNATGCCNGGNACNGAYAARTAYGAYAARTAYTTY CAYAGYAGYGGNACNYTNTTYCARGARACNGCNGCNTTYMGNGCNMGNCARGARYTNGCN MGNCARCARMGNGARGARYTNYTNMGNNNNAARGARAARAAYGARATGATGYTNAARGGN AARGGNAARAARGAYGGNATGMGNCCNGARAGYCCNGGNMGNAARMGNMGNYTNAGYCAY MGNCCNACNYTNCCNYTNMGNCAYYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNMGNATHMGNMGNGTNGTNGGNGGNCARCAR YTNGCNATGGGNGARTGGCCNTGGYTNGTNTCNYTNAAYTAYAARGARCAYCAYGCNTAY YTNGARYTNCARGGNYTNGAYCAYYTNTGYGGNGGNACNYTNATHCAYMGNYTNTGGGTN ATHACNGCNGCNCAYTGYGTNCAYCAYATNTCNGGNAGYGARGGNYTNGGNGTNCCNTCN AAYTGGATHGCNGTNYTNGGNGARTAYAAYMGNMGNGTNGARGARCARACNGARCARMGN YTNGARGTNGARCARATHTTYATHAGYCCNCAYTAYAGYYTNAAYCCNAARYTNACNGGN GAYATHGCNYTNYTNAARYTNMGNGARCCNGCNMGNGTNACNAGYTCNGTNAARMGNYTN AARGTNGAYGAYYTNMGNTTYATHCCNGAYMGNTCNGARTGYAARGCNGCNGGNTGGGGN CARCAYTCNCCNGAYGAYTAYGGNCARCCNCARTTYGGNAAYGGNACNATGGTNCCNCAY GTNGTNAAYGTNAARAARGTNTCNACNMGNAAYTGYCARGAYGCNTAYGGNGARYTNTGG CCNYTNATHGAYMGNACNGTNATHTGYTTYCAYTCNGAYCARMGNAARGAYACNTGYAAR GGNGAYTCNGGNGGNCCNYTNGTNTGYATGAAYGAYGAYGGNAARCCNGTNYTNACNGGN ATHGTNTCNGTNGGNGTNGGNTGYGCNYTNGARGAYTAYCCNGGNATHTAYACNMGNGTN GGNAGYTAYMGNAAYTGGATHGTNTCNACNYTNMGNGARAAYACNCAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TGYAGYMGNCARAARCCNATGAARATHYTNATGCARGGNYTNGAY GCNGCNGGNAARACNAGYYTNYTNTAYGTNYTNAARYTNGGNGARATHGTNACNACNATH CCNACNATHGGNTTYAAYATHGARACNATH---AAYTGYAAYGGNYTNGARYTNGTNGCN TGGGAYGTNGGNTGYMGNGGNAARATGMGNCCNYTNYTNMGNCAYTAYTAYCCNGGNACN GAYGGNATHATHTAYGTNGTNGAYTGYGGNGAYYTNGARMGNATHAAYCARTCNYTNGAY GARYTNAAYAARTTYGTNATHCARGARGARGARATGCARAAYACNGTNGTNATGGTNYTN GCNAAYAARCARGAYYTNCCNAAYGCNGTNAGYGCNGARCAYATHGARTCNAARATHAAR GARATGTGYACNTTYAGYACNGGNGTNTCNTTYTTYGTNATGCCNTGYAGYGTNACNAAY ATGGAR------GGNYTNCARCARGCNTTYAAYYTNTTYGCNMGNCAYATGAAYATGAAR AARGARGGNAARYTNCARGCNGGNYTNATHCCNTCNGCNTGGGAYGTNGCNGARGARACN GAYGAYGTNACNACNGARGGNGGNGAYTCNTCNAGYACNTTYTTYAARGAYCCNYTNAAY TGGYTNAARTCNGTNYTNTTYTAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TTYACNATHATGYTNGAYGARGTNGGNATHCAYGCNGTNGAYTGYYTN GCNTCNAAYATHYTNCAYGAYGAYYTNACNGTNGTNACNGTNTTYGCNCCNCCNAGYYTN GCNCCNAARATGAAYATHAAYAGYYTNYTNACNAAYGAYAGYAGYGARTCNATGAARTCN GGNCARMGNGCNGARGTNAARTGYTCNGTNGARGGNGGNTAYCCNGAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNAARGGNGCNTTYTTYATHCARGARTGYGTNCCNGAR ATHYTNGARATHAARMGNTCNGTNTGGTCNAARATHGAYAAR---ATGGAYYTNGAYGCN ATHYTNTCNTCNTCNACNAGYGCNYTNYTNCCNTCNGCNATHTCNGARGGNYTNGAYCAY AARAAYMGNTTYATHATHTGYCAYCCNACNAAYCCNCCNTAYTAYGCNCCNGCNACNGAR GTNGTNCCNTCNACNTGGACNGAYAARGARGTNATHACNMGNACNATHGARYTNYTNGAR GARGTNGGNCARGTNCCNGTNYTNGTNAARAARGARGTNAGYGGNTTYGTNYTNAAYMGN YTNCARTAYGCNATHATGGGNGARGCNTAYMGNYTNGTNAARGAYGGNGTNGCNAGYGCN AARGAYGTNGAYYTNATHATGTCNCARGGNYTNGGNGTNMGNTAYGCNTTYATGGGNCCN TGGGARACNGCNTAYYTNAAYGCNGARGGNATGAARGTNTAYGGNGARMGNTAYAGYGAY ATGATHYTNGCNATHCARCARGAYTTYAARGCNCCNGARMGNATGGARGGNGARACNYTN CARYTNATHCARGARGARATGGARAARGTNGCNGGNCCNGTNGARGAYATHYTNCARMGN MGNCARTGGMGNGAYMGNMGNYTNGTNGCNYTNGCNAARYTNAARGCNGAYATGGAYAAR ACNGAYGCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------YTNCCNGARCCNAAR GGNACNGAYGARTAYTTYTGYCAYGARTAYTGGTTYACNCAYAAYGARYTNAARYTNGAR GAYTTYGTNAARGARAARGARYTNGAYMGNCARYTNAARGTNCARGAYGCNAARGAYAAR GGNGARYTNTAYGARTGYAGYTGYTGYTTYGAYGAYGARTGYYTNTTYGARGAYYTNGCN CAYTGYCCNGARGGNCAYYTNTTYTGYAARGTNTGYGTNGTNMGNTCNACNGARGCNGCN TTYGGNGARATGAARACNMGNTTYCCNTGYYTNACNGGNATGTGYGAYCARAGYTTYGCN YTNAGYACNYTNCAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNACNTGGTGYMGNAAYATHACNYTNTCNAARACNATGMGNCAR GAR------GARGARCARCCNGAYGTNGARACNGARGTNGTNCCNAARMGNAARGTNGTN GAYGTNGARACNAGYATHMGNTAYYTNAAYAGYAAYGCNTTYGTNGARGGNTAYGGNGAR AARCCNGTNTGGTTYCAYTAYMGNMGNAAYTTYAARGGNAAYATHATGCCNCCNACNMGN AARAARTGYGTNMGNAARGGNGARATHGCNACNTCNAGYCCNTGYCCNGTNTGYMGNGAY GARTAYYTNATHYTNGAYGCNAARAAYACNAARYTNYTNGAYCARTTYATHTCNCCNCAY ACNGGNGARATHTTYGAYTCNATGAARACNGGNYTNTGYCARGAYCARCARMGNAARYTN ACNGTNGARGTNATGAARGCNTGGGAYCARGGNCAYYTNGARATGAARGTNCCNATHMGN ACNTAYAAYTAYGAYGAYTAYAARAGY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CCNTGYGAYMGNGTNGTN TTYATHGAYTGYACNTGGAAYCARACNMGNTGYATHATHGAYGAYGARMGNYTNAARGGN YTNAARAARGTNGARYTNAARTCNGARTCNACNCAYTTYTGGMGNACNCARGAYGGNATG CCNAARACNTAYYTNTCNACNATHGARGCNATHTAYTAYTTYTTYMGNGARTTYCAYACN ATHTTYGTNGAYCCNGTNTAYMGNAAYGARTAYGAYAAYYTNATGYTNTTYTTYTGYTTY ATGTAYGAYAARATHAARGAYAGYAGYACN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARGAYMGNACNGAYGTNTCNGTNCCNGARGGNACNGARGAYAGYMGNGGNCARGGN CARTGGAARTCNGCNGARCARCARTAYTTYGCNTCNGCNGTNYTNGCNCARAARAGYGAR ------------CARGARGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------YTNAARGARGTNCARGARGARMGN GAYAARYTNYTN------GARGAYCARCAYGARATGAARATHAARGAYYTNCARGGNMGN YTNGCNATHATGTCNMGNGARAAYGARGARAARGAYGARMGNATHCAYAARATGAAYGAR GARYTNAARATGACNYTNAARAARYTNAARGARACNGARCAYMGNYTNGCNYTNTCNGAR CARGCNAAYGCNTCNGCNTCNGARGCNCCNAARTCNAARACNTGYTCNGTNATGATGAGY AGYGCNAARACNCARTAYGARACNTTYTAYATHAARYTNGGNGARTTYATHGAYGAYTTY GGNTCNAARYTNACNTCNGAYGCNCCNAGYATHYTN---CARGAYYTNAGYTTYGTNACN AARATHATHACNCCNAGYGAYCCNGCNTTYGAYAARGAYGAYGCNAARTAYGTNGCNAAR CARATHATHYTNGTNAAYAAYGTNGTNACNTAYATHYTNAAYAAYGCNGAYCARTAYGTN GCN---GAYACNGCNTGGTGGGARGGNCARAARAGYAGYYTNMGNATGTAYGTNATGTTY AAY---AARATGGCNYTNACNACNYTNAARYTNACNGARGAYATHGAYGAYGAYGTNCAR AGY---GGNATGGGNGGNGTNAAY------------------------------------ ---------------------------------------ACNTTYAARAGYGAYATHAGY YTNGAYAARYTNTAYCCNAAYTCNAAYATGGAYTAYYTNMGNAAYAGYAAYCARAAYGAY GARTCNMGNGARACNGGNGAYACNTTYTCNGGNCAYGTNCCNATHGARCARYTNGARATH AGYCAYAGYMGNAGYAGYGGNCCNGGNGGNCARAAYGTNAAYAARGTNAAYAGYAARGTN GARATHMGNTTYCAYYTNGAYTCNGCNTCNTGGATHCCNGARTGGYTNAARCCNMGNATH TCNYTNCARGARGARAAYAARATHACNAARGAYGGNTTYYTNGTNATHAARTCNGAYATG ACNMGNAARCARATGYTNAAYCARGCNGAYTGYYTNAAYAARYTNMGNAAYATGATHCAY AARGCNTCNATHYTNCCNAARGARCCNACNGARGARGAYACNAARATHAARGARCARMGN ATGGTNAARGCNAARTCNGGNATHYTNMGNGARAARMGNMGNAARTCNYTNYTNAARAGY TCNMGNTCNAAYCCNGAR---TCNTCNCARGCNGTNAGYCARYTNMGNTAYAAYCCNTAY MGNAARTCNTCNYTNGCNTCNGTNACNGARGAYGGNGTNATHTCNTTYTGGGAYACNAAY ACNMGNAGYYTNGTNMGNGCNTTYGAYGTNGAYCAYCARGCNCCNGCNACNGAYYTNGCN TTYTCNCCNGTNAAYGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY GGNTCNTCNTGGCARGGNTGGTGGAAYGCNGARTTYAGYCCNACNYTNYTNTCNMGNATG ACNGCNATGATHYTNTGYAAYGCNAAYMGNYTNGCNGAYYTNMGNACNMGNGARTGYTAY AGYGAYAAYCAYTGGTCNATGTGYGARGCNATHYTNGARAARTAYTCNCCNTGYAGYAAR ATGCARGCNGCNGAYAAYATHCCNAARATGCARGARYTNYTNAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGGARGTNGAYGARGAYGTNMGN---CCNTCNTAYYTNAAYATH YTNATGCARGAYGAYATGGCNTCNGAYYTNYTNTCNTCNATHGTNGAYYTNAARAAYGCN GTNATHGGNAGYAAYMGNGARAARTCNMGNGCNATHCARCARGGNYTNGTNCCNMGNYTN YTNAGYTGGGTNGARGARGARYTNTGYCCNATGGAYYTNAARACNGARTCNGCNATHGTN YTNGGNAGYYTNGCNAARGGNGGNMGNGAYACNGTNGARAARYTNGTNGAYGCNAAYGCN GTNCCNGTNYTNYTNAARTCNATHAAYACNTCNAAYYTNAARTAYAGYGARGCNGTNYTN MGNTGYYTNMGNTCNATHTTYATGGARAAYACNGAYGGNATHGAYTAYYTNTAYGARGAR AAYAGYTAYGGNAARTCNTAYATHCCNACNTTYYTNGTNATGACNCARCARTCNACNGTN TGYCARGARTGYGTNACNAAYATHYTNGTNTGYTGYTGYAARACNMGNGARCAYCARATG TGYYTNYTNGAYAGYCARGCNYTNACNATHYTNTCNCCNYTNYTNCARTCNAAY---CAR TAYAARATHCARATGCCNACNYTNMGNTGYTTYGCNAARATGTGYTAYAARAAYCAYGAR GTNTGYTCNGCNATHGCNAARGAYAAYAARTTYGTNGAYACNTTYGTNGGNYTNATGAGY MGNGGNAARCCNACNGARATGCARATGGCNGCNGCNGARATGYTNACNAAYYTNCAYMGN TGYGGNGTNATHCCNTCNAGYGAYTTYGTNATHAGYMGNAARACNYTNGGNACNYTNGTN MGNATGTGYATGMGNGAYMGNACNYTNGARGARAAYGTNMGNGGNGCNGARATHYTNGCN TAYYTNGTNGARATHGARCCNGAYYTNCARGTNATGGCNAGYTAYACNTTYCAYYTNATH GGNGCNYTNTCNAAYTGYYTNCAYTAYCARGAYATHAGYAARACNTCNACNAGYGGNAAR CARGARGTNGAYTGGGGNAGYGARATGMGNAARGCNGCNTTYYTNGCNTTYGCNTCNATH AGYGCNAAYGAYGARGARATHMGNGARAARGTNATHAARCARGAYGGNATGATHGARCAR ATHCARACNTCNYTNTCNAGYCARCAYGARGGNGARGTNGCNGCNAGYYTNMGNTGYYTN CARTCNYTNACNMGNTCNGTNCARCARATHMGNACNTTYYTNCAYGAYAAYGCNGTNTGG AARCCNYTNYTNGARAARGTNMGNTCNGGN---------------AAYMGNGARATHATG GTNYTNGCNATGTCNTGYYTNTGYAAYYTNGTNYTNGARTTYTCNCCNAGYAARGARGCN YTNGTNGARCAYCAYGCNGTNGAYGTNYTNTGYGARYTNTGYCAYAGYGAYGAYAAYATH GTNMGNYTNAAYGCNACNTGGGGNATHATGTCNATGTCNTAYTGYGCNTCNGARGARYTN MGNATHAAYATHATHAAYAARATGGGNACNGAYACNATHGTNMGNMGNATHCARGAYCCN ATHYTNYTNATHMGNGARAARACNYTNTGYATHATHMGNAAYYTNYTNACNGGNAARATG ACNATHGAYAAYACNGTNAARYTNYTNGGNAAYGARGTNATHGARGCNGTNTTYAARGTN YTNTCNGAYCCNGAYATGCCNTGYAGYGTNGTNACNCARGCNYTNTGYGCNYTNAGYAAY ATGGCNGAYGGNCCNTCNTGYAARGCNTAYATGATHGGNAARACNGAYGARATHAAYTCN GTNGTNAARTAYYTNCARTAYCCNGARAARCAYYTNCARYTNCCNGCNATHCARTTYGTN AGYAAYYTNGTNGAYACNAGYGAYGAYGAYTTYGGNCCNTTYCCNMGNGCNGGNTCNTAY CARMGNATGYTNCARYTNAARACNYTNGGNGTNCARACNMGNYTNGARAGYYTNATHGGN ACNGGNATGGARGARGTNGARCAYMGNGCNCARCARGCNYTNAARTTYTTYGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------MGNYTNTTYGCNTGYTAYAAYGAYGGNATHATHAAYYTNYTNGAR AARTAYTTYGAYATGAAYAARAARCARTGYAARGAYGCNYTNCARYTNTAYAARAARTTY YTNGTNMGNATGGAYAARGTNTCNGARTTYYTNAARGTNGCNGARAAYATGGGNATHGAY AARGGNGAYATHCCNGAYYTNGCNAARGCNCCNGCNAGYYTNYTNGAYGCNYTNGARCAR CAYYTNGCNTCNYTNGARGGNAARAARTCN---GCNACNACNCCNACNGGNTCNAGYAAR CCNTCNGGNTTYAAYGCNGCNYTNAAYAAYATGTCNAGYAAYACNTTYAAYGTNAGYGAR GCNGARAARAARMGNATHYTNGARGARGARAAYCARCARYTNCARMGNCAYAARGGNYTN CAR------GARCAYAARYTNAARGAYAAYACNTCNCCNCARAARYTNGCNGCNCCNGCN GCNAAYAAYCCNTTYTCNACNGCNAGYCCNCARCAR------GGNCARTCNGAYYTNTTY GGNTCNCCNGTNGARAAYAGYGGNGCNGGNGGNAARYTNAAYAAYGAYYTNYTNAGYYTN GGNTCNAAYCCNTTYGTNGGNGGNGTNCARGAYGTNATGGGNTCNGCNTAY--------- CARCCNCARGCNAAYAAYAAYCCNTTYGGNACNGCNGCNTTYCARACNAAYGGNTAYGGN GCNCCNTCNAAYAGYTTYACNTCNGAYGCNGAYTTYGCNAARGCNTTYACNACNGGNTCN ACNAGYGCNCARGGN--------------------------------------------- TTYGAYGCNTTYGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CAY TCNMGNMGNMGNYTNGGNCCNTTYYTNATHAARATGYTNGARAARATHAGYGGNYTNGAR TGGCAYGAYMGNGAYAAYAARYTNTTYAARATHTCNTGGACNGAYAARMGNAGYACNCAR TGGTCNAGYGARGAYAAYATHATHYTNAARAARTGGGARATGTAYAAYAAYMGNTAYAAR GARGGNGARCCNGARAAYTGGACNGCNTGGAARCARACNTTYMGNAAYGCNYTNAAYAAR AGYCCNGAYGTNCAYGCNATHGARAARTCNCARYTNAARAAYACNTCNATGCCNTTYAAR GTNTAYAARTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARAAYCCNMGNGGNAARGGNMGNGGNMGNGGNMGNGGN MGNGGNMGN------------GGNGGNGGNCARGGNCCNGGNGAYAARTCNCCNMGNCCN MGNACNTGGTCNGGNGGNGAYGAYMGNTTYGTNGARTGYCARAARGARATGYTNGTNGTN AARTTYGAYAAYACNGCNGGNGAYAAYACNGTNGARGTNGARTAYGAYAAYGGNGCNCCN YTNTCNCCNACNCCNTCNTCNAARTCNTCNGGNTCNAAYCCNGGNMGNGGNCCNACNGGN MGNACNCCNAAYCARGGNGTNAAYGCNMGN------CCNAARGGNAGYAARGCNCCNAAY AARCARGAYAARTTYCCNAARGGNAARATHGGNAGYGGNMGNGTNTCNGGNCARCAYCAY CAR---------------GAYGTNGAYGCNGAYTGGGARAAYCCNGTNAAYCAYMGNCAY TCNTAYGAYGGNGCNAARGTNMGNACNACNTCNCAYTCNCARAGYCAYGGNGAYAGYGAR GARTGGGARGAYTGYACNGARTCNTCNGGNGCNCCNGAYGAYGAYGAYYTNGCN------ ---GAYGGNAAYCARAAYYTNYTNYTNGAYTGYCARYTNAAYCCNGARGCNCCNGARTTY YTNCCNACNTCNCCNGAYTTYYTNAARACNCCNCCNGGNCAYGTNAARGTNYTNAAYTGG GCNGGNAGY---AAYAGYCCNACNTCNCCNYTN--------------------------- ------------------TCNAAYYTNAGYCARCCNTCNYTNACNTCNACNTCNCCNMGN ACNAGYTCNATHCARTCNCCNGTNTCNTCNCCNGGNTCNTCNGCNTCNACNMGNGCNATG AAYMGNMGNGARCARATGGAYGARATGCCNGARGCNGAYGARCCNCAYCCNCCNCCNTTY YTNYTNGAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GTNTCNTTYCAYCCNGAYATHMGN MGNGCNACNYTNYTNAARGAYYTNAARTTYTAYTTYYTNTCNGCNCAYCARTTYAAYAAR ACNAAYYTNGCNGTNTCNACNGCNGGNGGNYTNCCNATHYTNYTNGARGAYGGNATGGAR GARGAYGCNGARGTNATGACNCARGAYGGNACNATHGTNGTNGCNGTNTCNMGNGAYGTN YTNACNTCNYTNAGYCCNACNTGYCARAARTTYGTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TAYGGNAAYGAYAAYAGYAGY GTNAAYMGNCARTCNMGNACNCARAGYACNMGNCCNGAYCCNATHCCNGGNCARCCNTAY GCNGGNGCNCCNGCNCARMGNGTNGGNAGYGCNCCNYTNMGNAARATGGGN---AAYCAR CARGGNACNATHMGNACNAAYGGNACNYTNGTNAAYMGNTCNGARYTNGGNGARACNACN ---------GAYGTNCARTCN--------------------------------------- CARCAYCAYCARAAYTTYYTNCCN------------------CCNATGCCNCAYCCNCCN CARGCNTCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MGNAGYMGNYTNYTNGARGAYTTYMGNAAYAAY MGNATHCCNAGYYTNTCNYTNAARGAYYTNATHAAYCAYGTNGTNGARTTYTCNCARGAY CARCAYGGNTCNMGNTTYATHCARCARAARYTNGARMGNGCNACNCCNCARGARAARGCN ATGGTNTTYGCNGARATHATHTCNGCNGCNTAYTCNYTNATGACNGAYGTNTTYGGNAAY TAYGTNATHCARAARTTYTTYGARTTYGGNTCNCCNGAYCARAARCARACNYTNGCNCAR MGNGCNMGNGGNCAYGTNYTNCCNYTNGCNYTNCARATGTAYGGNTGYMGNGTNATHCAR AARGCNYTNGARTCNATHCCNTCNGAYATGCARGTNGARATHGTNAARGARYTNGAYGGN CAYGTNYTNAARTGYGTNAARGAYCARAAYGGNAAYCAYGTNGTNCARAARTGYATHGAR TGYGTNGARCCNGAYTTYYTNCARTTYATHATHGAYGCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGAGYACN TCNGTNGGNACNATGMGNGCNGGNTCNAAYAARYTNTCNGGNCCNAARGARAARCCNGCN AARGGNGAYAARGGNACNGCNTCNTCNCARGTNACNGTNATHAARACNGARGGNCAYTCN AAYAARATGCARCCNACNCARGARCARYTNMGNYTNGCNCARATGATGAGYACNAAYCAR ACNGAYGCNGAYCCNAAYACNGTNAARCARYTNATGGAYATGACNGGNAARAGYGARGAY GTNGTNGTNATHGCNYTNCAYGAYGCNGGNAAYGAYGCNGAYMGNGCNGTNATGATGYTN YTNGARGGNGGNGAYGARCARGGNGARTGGYTNGARCARGGNGGNAARAARAARAARAAR ---AAYACNCARAARGARAAYACNAAY------AGYGARGAYCARTCNGARGGNMGNAGY AARGAYMGNGGN------------ACNGAYAARAGYGGNGAYCAYCARGAYYTNCCNCCN MGNMGNGGNMGNMGNAAYGGNGTNCCNCCNCCNMGNYTNGCNMGNGGNMGNGGNMGNGAY AARGGNAAYTTYGGNGAYMGNGAYAARGARMGNAAY---AAYGTNATGGARGAYTGGGAY AAYAAYGARAARGAR------------------GARAARGGNCCNMGNAGYGAYGGNGAY MGNGGNMGNTCNMGNGGNMGNGGNGGNTTYGGNGGNMGNAARACNGGNGGN--------- GGNGGNGGNGGNGGNMGNTTYGGNAAYAGYAAYGAYMGNGARAAYMGNGGNTAYAGYMGN CCNMGNMGNTTYGARAARATGAAYAGYTCNCARCCNYTNGAYGGN------CCNGARATH GAYACNTGGACNAAYGARACNGCNGARACNAAYGTNACNAAYAARGAYACNGAYTGGAAY AGYTGGAAYGAYTCNTGGGTNAAYGARGARGAYCARTGGACNGGNACNYTNGAYGARACN AARGTNTTYACNCCNTCNCAYGTNAARATGCCNGARCCNGAYCCNGTNAGYAAYGARCCN CCNAGYTCNYTNGGNCARMGNYTNGAYGTNGGNAGYYTNTTYGARAAYGCNAARTTYACN AARGCNCCNGAYTAYAGYAARCCNAGYGGNGAYTCNTAYATHACNCARTTYAAYCARGCN GCNACNGARTCNATHAARAAYACNATHGGNATHGGNAGYACNTCNMGNCCNCARATHGGN ATGTCN---------------CCNCARAAYTCNTCNAGYTCNYTNGGNYTNTCNAAYYTN GGNCARAAYTCNGGNCARGTNCARGGNAGYTCNGTNYTNTCNCCNYTN---CARCARACN GGNTCNCAR---AAYTCNATGCCNCAYGCNATGGCNCARYTNTCNCARATHTCNCARCCN GCNTCNCARTCNCCNAGYATGTCNCARATGGGNATHGGNTCN---CARCCNTCNCARGTN AGYAGY------------------------------------------------------ AGYCARGCNCCNCARCARTCNMGNATHCCNGCNGTNATH--------------------- CARCARCARAAYYTNCCNCARACNAGYATG---AAYAGYATGCARCARMGNCCNAARCCN CARMGNTCNAARYTNCCNCCNCCNTCNAARATHCCNTCNACNGCNGTNGARATGCCNGGN CAYATHCCNMGNAAYCCNCARYTNGAYGTNCARTTYGGNYTNGAYTTYGGNTCNGARCCN TCNGTNCARTTYGGNTTYGGNGGNAAYGGNGAYAGYACNGCNGTNACNAGYTCNTTYTCN ACNACNTCNAAYGGN---ACNACNGTNATHTCNAAYCAYYTNAAYCARGGNCAYGTNAGY CARTCNGCNGGNGAYGGNAAYTCNGTNTCNACNATHATGCCNTCNCCNTCNGCNGGNTCN TCNAARGTNCCNTCNGGNATHGARCCNCARGTNTCNAAYMGN---CARGGNGTNTTYCAY AAYTCNGTNTAYTCNTCNTCNCARCARAARAAYGARAGYCARACNYTNGARMGNGAYCAR AAYAARGTNAAYGAYTCNATHCCNTTYYTNCCNTCNCARYTNGARMGNAARGCNAGYCCN ATGCCNTCN---CARMGNCCNGGNCARACNAAYCARAAYYTNAGYTCNGGN------CCN ATGACNTCNAAYAARGAYTCNACNGGNGCNGTNGCNAAYAGYTAYTCNTCNGCNAAYGGN TAYCCNTCNTCNTCNTAYCARAGYCAYACNAARGGNTCN---------ATHTCNCAYACN GCNAAYTCNCARCCNTCNCARTCNTCNTCNTTYCCNGGNCARTAYCCNGTNAAYCARTCN ---TAYCCNTCNGCNGGNCARACNCARTTYCCNGCNCCNCCNAAYACNACNCCNTTY--- CCNTCNGCNCARCCNACNCARTAY---------AAYTCNAAYCCNTCNCARAAYCARTTY TCNTCNGGNCARAAYCARTTYTCNGTNGGNACNTCNACN---------YTNTCNCAYCAR AAYCARTAYTCNAGY---GGNCARAAYAAYTAY---GGNGGNGGNCCNTCNCARTAYTCN GGNTAYCARAAYAAYAGYTCNTTYCCNCCNCAYCCNCARTCNCARTCNAAYTAYTCNAAY CARAAYGGNGGNGGN------GGNGCNYTNTAYCCNACNTCNACNCARTCNGGNGTNTCN CCNTAYACNTCNCARTCNAAYTCNTAYCARTCNCCNTCNGCNGGNTCNTAYCAY---TCN MGNGAYGGNCCNACNAAYATGGTNGTNAGYACNCARTCNAAYAGYGGNATGTCNTTYCCN AGYCARCCNCARAAYTCNAAYYTNAARCCNGCNGCNACNCARAAYAAYTCNAGYTTYAAY TCNCARACNTAYAAYGCNAAYCCNACNCCNYTNCARCCNCCNTCNYTNGTNAAYAARYTN GGNGARGGNYTNTCNAARATHTCNATGAARGAYTCNACN------YTNGAYAGYCAYCAR TCNTCNCARTAYGARCAYACNCCNTCNGTNGCNAGYGTNCCNACNAGYGTNAGYYTNCCN TCNGCNTCNAGYTCNGCNTCNYTNTCNACNGGNACNAAYACNATHTCNTCNACNTCNACN GTNACNTCNATHTCNTCNGCNTCNMGNGTNACNTCNATGCCNTCNACNTCNGGNAARGCN CCNCCNAAYYTNCCNCCNGGNGTNCCNYTNATGGGNCARTAYATHATGGGNCARAGYACN ATHCCNCCNTTYTAYAGYGTNCARCCNCCNYTNTAYGGNTAYGARGAYGTNCARYTNYTN CARCARMGNATGCCNATGCARACNGGNAGYTTYTAYGAYGTNAGYGCNTTYCCN---GCN CCNGCNGGNCCNACNYTNCCNACNGGNMGNGAYCARCARCCNCCNATHCCNAGYGTNCCN TTYTCNGGNACNTCNGAYACNAARYTNACNMGNGTNGAYGCNCARAGYCCNAAYGCNTCN AGYCARCCNCARAGYGCNCAYTCNGCNGCNCARCARCCNYTNTTYAAYTTYCAYTAYGGN TAYTAYTAYCCNTCNATGTTYCCNGGNGCNGCNGGNYTNCARTAYCCNACNACNGTNTAY CCNATHCCNCCNGTNACNAAYGCNGCNGCNCAYCCNGGNACNACNTCNACNACNCARTAY CARAARTCNTAYACNTCNCAYGTNTAYACNACNAARGGNTAYGAYGARGTNAAYCARGTN CARGAYTTYTCNAARACNGGNTAYGGNAGYTCNCARAGYTCNGGNAARGCNTCNGGN--- ---------ACNMGNTCNGGNACNAAYGARATHACNCCNAAYGCNTAYAGYAARTCNCAY GGNCAR---GGNTTYGAYAARCARGGNTAYCAYGGNGGNACNCCNCCNCCNTTYAAYYTN CCNYTNGCNTCNGCNACNCARACNGGNCCNATGGGNGCNCCNACNACNCCNTAYGGNGCN CCNTTYYTNCCNGTNATGGCNGCNCAYCARCCNCAYTCNCARATGATGCAYCAYCCNATH CARCARGAYTCNAAYAGYAGYAGYTCNMGNGGNYTNAAYCCNGCNGGNGGNCARGGNAAR TCNGGNACNGCNAARTCNTTYGGNGGN---CCNCCNTAYTGGAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGGNATHYTNGAY YTNTTYAAYGCNAGYCAYGTNYTNAARYTNMGNYTNGTNGTNTAYGCNGTNYTNGTNTTY TTYAGYTTYTTYATHATHATHGGNGTNGCNGTNATGAARGAYAARGARAGYTTYGAYMGN TGYCCNYTNTAYYTNAAYGAYGGNGGN---------TAYTAYGGNTCNTCNGCNAAYTGY AGYTAYCCNATGACNATHGCNATHATHTTYCARYTNGTNTTYYTNYTNTTYMGNGTNGCN ATHYTNGTNYTNGCNYTNATHGGNAARYTNTCNTCNGAYTTYTTYATHTTYTCNGAYATH TTYGARYTNATHTAYGTNGTNGTNGAYYTNGTNGCNTTYTTYYTNACNTTYGTNGGNGCN TGYATHYTNTCNGCNGGNTCNAAYGCNTCNCAYTCNGAYTAY---------CCNTTYGCN TGG---------MGNCCNGCNTCNMGNGTNTCNCARGCNGGNGCNTGGATHAGYACNTTY YTNTGGYTNTTYATHGGNYTNTGYGGNTTYATHTGYYTNTGGMGNTCNGGNAARATHCCN TTYATHGGNGGNMGNGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNGGNMGNYTNGAYATGCCNATGGCNGCN ACNGTNAGYAARCARAAYCCNGTNTCNCCNTGYTCNATGGTNATGTCNATGYTNTAYGCN AARMGNYTNMGNCARMGNAGYAARCARTAYYTNCARTCNATGTCNTCNACNGAYGTNTTY TTYATHTCNATGATGATGGCNAGYAARTAYATHTAYGAYGARGGNGTNGAYGARGARGTN TAYAAYGAYGARTGGGCNACNAGYATHGGNCAYGAYGTNGARGAYGTNAAYCARATGGAR ATGGAYTTYYTNAARGARATGGAYTGGCARYTNTTYGTNAARCCNGARGARTTYGAYCAR GCNYTNACNGCNATHGARMGNMGNYTNGCNYTNAARGARGGNGTNAARMGNGGNTGGTTY ACNTAYACNGARYTNGCNGTNYTNYTNGAYTGGGAYCCNGTNTAYAAYYTNTGGAAYCAR GTNGGNYTNGAYTGYACNAARGTNGTNTCNYTNYTNTCNGCNGTNTAYGTNGCNAGYYTN GTNAGYATGATGGGNTCNGCNGCNATHGCNYTNCARGTNTCNGGNCCNATGGCNACNGCN ACNYTNGCNGTNYTNTCNTCNCAYATGTCNMGNTTYACNGCNCCNTGYCARCCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGTNTGYGTN CCNTGYTTYYTNATHCCNGTNATHYTNTGGATHTTYCAYAARTTYGTNCARCCNTGGYTN TCNAARATHTGGGGNAAYTCNGARAAYTAYGTNACNAGYAAYYTNACNTGYCCNATGCCN AARAARAARAARAARGTNGAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CAYCCNGAYGGNAARGAYATGCARATHAAYYTNACNGGNTTYYTNAAY GGNAARAAYGCNMGNATHTTYGTNGCNGARYTNTGGGAYCAYYTNTGYAGYGCNCARGAR AAYATHACNGGNATHCCNAAYGARTTYYTNGARCARAARAARAAYGARATHAARCARMGN CARGARGARCARGARMGNYTNCARGARCARYTNAARAARAARGARGARCARATHAARGAR CARYTNTCNMGNGARMGNMGNGARYTNGARAARAARGAYYTNAAYAAYYTNTCNCCNGAY MGNCCNAARYTNGTN---------------------GARAGYAAYGGNATHAARCCNGTN YTNGAYGGNGGNGAYGGNGGNGAYTCNAARGCNGARGTNAARTCNGAYGCNAARATHGAY GTNGARGCNGCNGGNGAYTCNAARCCNGGNGCNGARGTNAARAARGAR------------ ------------------TCNMGNGAYAARGARMGNGARMGNTCNCCNGARAARAARMGN GAYAAYMGNGAYMGNGAYMGNMGNMGNCAYTCNMGNACNCCNGAYAARCAYMGN---CCN MGNTCNMGNACNCCNGAYMGNCAYMGNMGNGAYMGNGAYMGNGAYMGNCCNGCNTAYGAY MGNGGNMGNTAYTCNCCN------------------------CCNMGNMGNMGNTCNMGN TCNCCNMGNMGNMGNTCNCCN---CCNMGNMGNMGNACNCCNCCNCCNMGNTCNGCNTCN CCNYTNMGNAARAARTCNYTNAARAARCCNGARGGNAAYMGNMGNGAYGGN--------- ------------------------------TCNAGYTCNGAYAGYAGYTCNAGYGGNTCN GAYGGNGAY---------------TCNAAYAARGARGAYTCNCCNGAYAARGCNGGNATH CARCARMGNMGNAAYTAYMGNAARCAYGAYGARGARAGYGGNAARGARTCNTCNTCNAAY TCNTCNGGNGAYGARMGNGARMGNMGNMGNCCNCCNCCNCCNCCNMGNGAYMGNMGNTAY GGNMGNAGYCCNTCNCCNMGNMGNMGNMGNTCNCCNCCNMGNMGNYTNAGYCCN------ ---MGNMGNCARAGYCCNCCNMGNMGNMGNTCNCCNCCNMGN------------------ ------MGNMGNATGAGYCCNATGCAYCAYMGNMGNAGYCCNTCNCCNMGNMGNMGNTCN CCNCCNMGNTAYTCNCCNCCNMGNMGNMGNAAYTCNCCNCCNCCNCCNMGNMGNMGNTCN ATGTCNCCNMGNMGNMGNMGNTCNTCNGGNTCNCCNCCNMGNMGNCCNCCNTCNCCNTTY MGNGGNMGN---MGNMGNCARTCNTCNMGNTCNCCNTCNGGNTCNCCNGTNAARMGNMGN MGNTCNCCNCCNGCNGCNTCNCCNCCNGTNMGNCCNMGNAARAARCARGCNTCNCCNCCN CCNTCNGAYTCNGAR------------AGYTCNGGNTCNGARGAYTCNTCNTCNTCNCCN CCNCCNAARAARMGNCCNGTNAARGGNAARGAR------------CARCCNCCNAARMGN CCNGTNCCNCCNGCNAARCCNTCNGCNCCNGCNCCNGCNAGYGAYAGYTCNTCNTCNTCN GGNTCNGAR---GAYAGYGAYGARGAYTCNGARTCNGARAAYGARYTNCCNCCN------ ------AARCARTGGAARGARGCNTCNCCNCCN---------------YTNCAYMGN--- ------------MGNGAYCAYAARTCNAGYCCNGCNCCNCCNGCNMGNMGNMGNCCNAGY ---------------------TCNMGNTCNMGNTCNCCNGTNCAR---MGNMGNGAYTCN MGNCCNAGYCCNCCNCCNGCNMGNMGNAARCCNGGNTCNMGNTCNCCNCCNCCN------ ------------CCNMGNMGNTCNMGNAARGAYACNGAYTCNTCN---GAYCARGARYTN GCNMGNMGNGAYMGN---------MGNCCNMGNGAYGCNCCNAGYCCNCCNMGNAARMGN CARGCNMGNTCNCCNTCNCCNMGNMGNGARAARGAYGGNGGNAGYMGNGAY------GAR MGNMGNMGNTCNCCNGTNAARGARAARCCNMGNGARATGTCNGAYMGNGCNGAYMGNAAR CARCARGTNGTNMGNAARGARAARMGNCCNCCNTCNTCNGAYAGYAGYAGYGGNAGYAGY TCNGARGARGARGARGARGARAARGAYTAYAARTCNAAR------CCNAARTCNGGNTCN AARCCNCCNATHGAYAGYGCNAARCCNGGNMGNMGNGCNTCNCCNGCNGTNGCNCCNAAR MGNAARMGN--------------------------------------------------- ---------TCNGARAGYGGNTCNCCNCCNCCNCCNGCNCCNCARGTNTCNMGNTCNTCN MGNMGNGAYGCNMGNGAYGAR------------GAYMGNCCNMGNAGYGAYCAYMGNTCN CCNAGYCCNAGYMGNGGNGCNACNCCNCCNMGNAAYGGNAAR------------------ ---------------------------------------------------GTNTCNGCN TCNTCNTCNTCNAARCCNAARAARGAYAARCCNCCNCARTCNGGNAGYAAYAGYGARTCN GARGGNTCNGAYTCNGAYAAYGCNTCNAARAARAARAARAARAARAARGAYAARAARCAY AARAARCAYAARAARCAYAARAARCAYAARCAYAARAARGAYGCNGGNCARATHCCNGAR AARGGNGARGAYYTNGARCARMGNYTNMGNGARAARGCNYTNATGTCNYTNYTNCAYMGN AARAARCARGCN---------------TCNGARAAYAARGAYTCNGAYAGYGGNAGYAGY AGY--------------------------------------------------------- ---------------------GGNGAYGAYAARCCNYTNYTNGAYYTNMGNGCNGCNGCN TAYCCNYTNTTYGCNAAYMGNAAYACNMGNMGNGAYACNTTYCAYCCNTGGGAYCCNGAR CAYACNCARAARCCNGCNGARYTNGTNGARYTNGGNTTYTTYTAYGCNGGNTAYTCNGAY TGYGCNMGNTGYTTYTAYTGYGGNYTNGGNYTNAARTAYTGGMGNCCNACNGAYGAYGCN GCNTAYCARCAYGCNMGNTTYMGNCCNCARTGYYTNTAYAAYTGYTTYGTNAARGGNCAR GAYTTYATHGAYMGNGTNCARMGNGARATHGGNCARAGYACNGCNCARTCNGAYAAYGCN GGNCARGTNCCNAAYATHGARMGNYTNATGATGTCNGARGCNGTNMGNCARGTNATHGAR GARGGNTGGACNMGNCAYCARGTNAARCARGGNGTNGTNCARYTNGTNAARGAYYTNGGN GARGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYGTNCCNAAYMGNACNYTNTCNTCNGCNATGGTNTTYAARCAY GARGGNGARMGNTAYCCNMGNMGNGGNTAYTGGGGNGAYACNGTNGTNTCNCCNTAYGTN ACNTAYGGNATHGARACNGARGARAARTCNTTYTAYAARAARCARAAYAARCARCAYACN AARACNGCNGARGAYGTNGCNGARTTYAAYATHACNTCNYTNYTNCAYGARYTNATGATG AARGARAARTAYGARYTNCCNAARGTNGARGTNAARGAR---AARGTN---GAYAGYGCN GARAARCARACNGCNACNYTNGARGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CAYAGYCCNYTNYTNAARGARMGNGGNTAYGTNGCNAAY CARATGYTNCAYGTNTGYGAYTGGYTNCCNACNYTNTAYAGYGCNGCNGGNGGNGAYGCN TCNAAYYTNACNAAYYTNGAYGGNTAYGAYGCNTGGGCNATGYTNACNCAYAAYGGNGAY GGNGTNMGNGAYGARATHYTNCAYAAYATHGAYCCNYTNGARAARAARGCNGCNATHMGN GTNGGNGAYTAYAARYTNYTNACNGGNGAYGTNAGYYTNMGNTGGGGNGGNTGGTAYCCN CARTGGAARYTNGAYGGNGAYGARCARYTNYTNCAYTTYTCNAAYTTYACNGAYAARTTY GTNGARAGYGARGARAAYAGYATHMGNMGNGGNGCNTCNGARTCNCARTAYMGNAARTTY TGGCAYTCNGAYGTNGAYGAYMGNYTNCAYGTNYTNTAYAAYTCNGAYTCNGCNCCNGGN AGYAAYTTYGARTCNGARACNGGNYTNMGNCCNGGNMGNMGNGGNACNCCNGTNAARYTN GAYTGYGGNGTNAARCCNYTNAAYGCNAGYACNAAYTGYCARCCNMGNAARTCNCCNTGY YTNTAYAAYATHTCNAARGAYCCNTGYGARTAYTAYAAYATHGCNCARGCNAAYCCNGAY ATHGTN---------------GTNTTYATHTCNTGYGTNATGYTNGTNGCNGCNGTNMGN MGNCCNMGNGGNGTNTCNYTNGARAARYTNTCNTTYTAYCARTTYGAYAARGARTTYMGN TGYYTNTCNGAYGGNAARATHTTYCCNATHGAYCAYGTNAAYGAYGAYTAYTGYGAYTGY GARGAYGGNTCNGAYGARCCNGGNACNTCNGCNTGYCCNAAYGGNYTNTTYTAYTGYGAR AAYAARCCNCAYAARGGNAGYTAYATHAARTCNTCNMGNGTNAAYGAYGGNATHTGYGAY TGYTGYGAYGGNTCNGAYGARTTYGAYGGNGCNATHTCNTGYTCNAAYACNTGYYTNGAR CARTTYGARCARGCNAARGCNGARCARGARATHYTNMGNMGNAARCARGCNGAYGGNTAY AARATHAARCARGARTAYATGCARCARGGNAARMGNGCNAARGAYGARAARYTNTCNCAR YTNTCNGARTAYGARAARGARAARGARATHYTNACNAAYGARAARGTNGCNGCNGARGCN GCNAARACNGTNGCNGARGARCCNGARACNATHGCNAARGARGARCAYAARAARGCNTGG GARYTNGTNAARGARGARMGNCARAARGCNAARGAYGCNGCNGCNGCNGCNCARGCNTTY GARATHYTNGAYGTNAAYAARGAYGGNMGNGTNGAYTTYCCNGARYTNATGAARCAYAAR GARTTYGAYATHAAYTCNGAYGGNACNGTNAGYGARGARGARGCNCARGARTAYYTNGAR GARTAYGTNCARGTNGAYATHGCNYTNTTYACNGARAARATHTGGCCNAAYATHAARGAR ATHTAYAARCCNCCNGCNGTNGCNGARACNGAYCCNGCNACNGARGGNGGNGCNGGNAAR GAYATHCCNGTNGAYGARGAYYTN---------GARGGNTAYAAYGAY---GARGARGAR GARGARGARGARGAR--------------------------------------------- ---------------GARGARAARGARCCNGARTAYAGYGARGARACNAARCAYYTNATH GARGCNGCNGAYGARGCNMGNAAYAARTTYGAYGAYGCNGAYMGNAARYTNMGNGAYCAY GARMGNGARATHGAYGARGTNAARAARTAYYTNGARATHGAYTTYGGNCCNAAYGARGAR TAYGCNGCNYTNAARGGNCARTGYTTYGARTAYACNGAYMGNGARTAYACNTAYMGNYTN TGYCCNTTYGAYAARAGYACNCARAARAAYAARAAYGGNGGNATHGARACNTCNYTNGGN ACNTGGGGNAARTGGCAYGGNCCNGAYGARGAYAARTTYGAYACNATGAARTAYGARAAY GGNCARGGNTGYTGGAAYGGNCCNAGYMGNTCNACNCAYGTNAAYYTNCAYTGYGGNTCN ACNAAYGARGTNACNAGYGCNTCNGARCCNAGYMGNTGYGARTAYCARTTYGARTTYACN ACNCCNGCNMGNTGYGARCCNCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNATHAAY GARTTYACNAAYYTNGTNGGNGARGGNGTNTAYTGYGTNTTYTAYTTYTGYGGNCAYGGN TTYGARGCNTCNGGNCARTGYTTYYTNYTNCCNCCNGAYGCNCCNCARGGNTAYAAYCAY ACNCAYTGYYTNTCNGCNGAYGCNATHYTNTTYAAYGTNYTNYTNCARAARAARCCNAAR ATHTGYTGYATGATHYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GGNATHAAYAARTAYTGYTCN ATHGTNCAYCCNYTNAGYAAYCCNATHAARYTNAARCAYATHGTNATHATGATGGTNGCN GCNTGGATHTGGGGNGCNTTYTGYGCNACNATHGCNGTNACNGGNYTNAGYMGNGTNAAR TAYAARAAYGGNACNTCNCARTGYGGNCCNGAYTAYCCNAARGARATHAARGGNTAYYTN TTYCAYGGNATHGTNCARACNACNGTNATHGTNYTNCCNTTYTGYYTNYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GTNGAY CCNAGYGAYGAYTCNGAYTCNGAYTCNACNAGYGGNCCNTTYGCNACNAARGGNMGNGTN TTYCARCARAAYGGNAGYATHAARCCNGGNAARAARACNAARGGNMGNGTNAARATHAAR ATGGARTTYATHGARAAYAARYTNMGNMGNTAYACNACNTTYAGYAARMGNAARACNGGN ATHATGAARAARGCNTAYGARYTNTCNACNYTNACNGGNACNCARGTNATGYTNYTNGTN GCNAGYGARACNGGNCAYGTNTAYACNTTY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATHATHCAYMGN MGNACNAAYCCNYTNAAYCARGAYATHYTNTCNTTYAARGAR---------TCNGTNGAY GGNTCNCCNTAYCCNATGCAYAARYTNATHYTNCCNTGYAARGARAARYTNCARMGNCAR YTNATGYTNTGYGGNAARYTNAARYTNAARYTNMGNMGNYTNTAYGCNTCNAARCARGAR YTNGCNMGNATGCAYCARACNATHAARAARAGYACNGTNGGNGTNAGYATHMGNCCNGAR YTNAAYCAYYTNACNCCNYTNGARGTNTTYYTNYTNMGNTAYCCNGAYAGYYTNGGNMGN ATGGTNCARATHYTNGAYGARGAYAAYGCNTCNYTNAARMGNYTNYTNGARTGGAARGAR AARGAYCAYGTNTTYTGGGARTGGATGGAYAGYGTNYTNACNYTNCAYATHCARGARCCN GTNAGYGARATHGAYYTNCARGARCCNGTNAARGARGARTCNGTNTTYYTNGAYACNCCN TCNGAYATHGGNGARMGNATHTCNAGYYTNMGNTCNTGYYTNMGNGAYTTYATHYTNGGN CAYGARGAYGAYATHGARACNYTNGARAAYYTNGTNGARGAYAARAARATHTCNCAYGGN GARYTNGARYTNATGAAYTAYCARGTNGARAARGARYTNATHGARYTNTCNAARAARTTY TCNAARTAYGARAARGGNAARTTYGAYATHCCNGGN---MGNGGNATHTGYTCNCARGAR TCNCCNATHGTNAARACNAAYAGYGTNTCNTCNAGYACNTTYGAYAGYGGNMGNMGNAAR AGYCARCCNCARACNGCNCARAGYATHAARGCNMGNMGNGARACNGARGTNTCNGARYTN GTNCARGARGARATHTCNGCNYTNCARAARGARGTNGARAARYTNGARCARGARYTNAAR CARGCNCARATHAAYAAYYTNAARAARYTNCARAAYTTYGCNGGNAAYAAYATHAGYTCN ATHTGYATHYTNCCNMGNTAYTTYAARCARTTYYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARGARATGTAYMGNTCNCCNYTNGAYTTYGCNAARGAYATHGGNAAYGCNATHACN GGNYTNGCNGAYTAYTTYGAYTCNGAYYTNYTNGARAAYGARGARGCNTTYAARGCNGAY YTNTAYCCNYTNGAYCCNGARGAYATHATGTGGTCNCCNGAYGAYGCNGGNGTNGTNTTY TGYGCNTGGGAYCAYGARCCNTAYMGNYTNGGNYTNAARCAYTGYTGYCARMGNAARGGN GGNYTNTAYTAYYTNGAYYTNCARAARGGNTCNGTNGARMGNYTNAGYCAYGARGGNMGN GCNGTNMGNTTYCCNMGNTTYAGYCCNGAYATGAGYMGNYTNATHTAYYTNGAYACNCCN GTNGGNGGNGCNCAYYTNCARTGYTGYMGNYTNGTNATGATHGAYTGGGCNACNMGNGGN AGYMGNGTNGTNGTNGAYGTNGTNMGNCAYGCNCCNGCNGCNTCNTTYCARGGNATHTAY GTNGCNGCNYTNCCNMGNAAYGTNTGGTTYGARGAYAGYGTNCAYYTNGCNYTNTCNACN GCNTGGMGNAGYGTNACNACNGTNGTNATHATHAAYACNGAYACNGGNACNGTNGAYMGN YTNTCNAARGAYGARAAYAARGGNTCNACNTCNYTNYTNGGNGTNGARAARACNAGYYTN ATHYTNGCNTCNTCNTCNYTNACNTCNCCNTTYCAYYTNGTNYTNGCNMGNYTNGARGAY GTNGCNAAYCCNAARTCNGTNCARTGGATHTAYCCNGAYGGNACNCCNGAYACNYTNGAY TGGGTNTCNTCNTGGGARGTNYTNCARCAYACNCCNACNTCNGAYMGNGTNAGYGCNAAY AAYGCNAAYYTNGAYTAYGARAGYATHYTNTGYYTNCCNCCNAARGTNAARGAYGGNAGY YTNCCNCCNYTNATHYTNTTYTCNCAYGGNGGNCCNCAYGTNGCNTTYGAYACNTCNTAY AAYYTNATHGCNAAYTTYTTYTCNYTNTGYGGNTAYGCNGTNYTNATGGTNAAYTAYMGN GGNTCNTGGGGNTTYGGNGARGAYGGNGTNGARTCNYTNYTNGGNGCNGTNGGNGAYCAR GAYGTNAARGAYGTNGARAGYGCNATGATGAGYGCNATHGCNAARGGNGTNGTNGAYGCN AAYAARGTNYTNGCNTTYGGNGGNTCNCAYGGNGGNTTYYTNACNACNCAYYTNATHGGN CARTAYCCNAARACNTTYAARGCNGCNTGYTCNMGNAAYCCNGTNATHAAYYTNACNTCN ATGTGGTCNACNACNGAYATHMGNGAYTGGATHTTYGAYGARGGNGGNGTNCCNTTYGAY ATGGCNTCNYTNATGAAYGARACNCAYTTYCCNAARYTNTGGAARTGYTCNCCNATGTTY TAYGTNGAYCARGTNACNACNCCNTAYTAYAARGCNMGNTGY------------YTNACN TAYCCNTCNAGYAAYCAYAGYYTNGCNGARGTNGAYGTNGARGGNGAYTGYATGGTNAAY ACNATGGCNTGGTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATH GCNGGNTCNATHATGAARMGNATHGGNATGGTNTCNTGYYTNTAYYTNGCNYTNYTNGGN TTYGCNYTNMGNTTYYTNTCNTAYTCNYTNYTNCARGARCCNTGGTAYGTNYTNYTNGTN GARCCNATHCAYAGYGTNACNTAYGGNYTNATGTAYTCNGCNGCNTCNTCNTAYGCNAGY TAYATHGCNCCNCCNGGNATGTCNGCNACNGTNCARGGNATHATGGGNGGNYTNAGYTAY GGNTTYGGNAARGGNATHGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGATHGCNMGNGARGCNAAYTCNTCNAARMGNCAYGAYTTYCARAAYACN TCNTTYGGNGAYGARYTNCCNTCNGTNAGYTGYGAYYTNGCNGAYYTNAAYATHTCNACN AAYGAYTTYGAYCARYTNYTNYTNGAYGGNYTNTCN------------------------ ---ATGGAYTGYGAYGGNCCNGCNCARAAYGCN---ACNGCNCARTCNTAYTGYGAYTTY AAYATGTTYYTNGARGAYAGYCARMGNCCNMGNGAYATGAAYATHTCNGARYTNACNGAR GCNAGYYTNACNGCNTTYTTYCARAGYYTNAGYAGYAGYGCNCARYTNAARGARACNGAY GCNACNCCNCCNTTYTCNGGNGGNAGYACNCCNCARACNCARTCNMGNGCNGTNTCNCCN ACNTGGAGYGARAGYAGYGGNAAYATGAGYGGNAGYAGYGTNTCNGGNCCNTCNTGYCCN MGN---AARYTNGCNCAYAGYAAYAAYYTNGTNCCNMGNCAYAARMGNCCNTCNCAYMGN MGNGCNGARGTNAARMGNMGNGAYAARATHAARACNTGYYTNGAYGAYATHAARYTNCAR GTNCCNTCNYTNCAYGAYAARGGNAARYTNAGYGARTCNGCNATHYTNTTYAARGGNCCN TCNAARAARCAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATHATHCARTCNGARYTNACNGGNGGNATHMGNTAYGAYTAYMGNACNCARGTNCAR ATHGARTCNGAYYTNGTNCAYMGNMGNATHATHTGYACNAARAAYCCNGGNCAYGARCAR TTYGTNCCNATHAARGARYTNGGNYTNGGNGAYYTNCCNGARTCNYTNAARACNGARGAR GTNYTNGARTAYYTNAARGCNYTNAGYAARYTNGTNGTNMGNATHCARGTNAARCAYACN AGYGARAAYMGNCAYAARGAYGAYCCNTTYATGTCNATGATHGGNMGNMGNGTNTTYMGN GGNGCNACNGGNAGYGTNTCNGGNGTNAGYGAYGGNAARGAYATHCARGARATHCCNTGY AARGAYGARTCNTGYATHYTNGGN------ATHGARCAYTGYCARTAYGGNTTYGTNGAR GTNMGNACNAAYMGNCAYYTNGCNATHGAYGCNAARGARGCNCARGARACNGARATHGAY TTYTTYTAYTCNCCN---MGNATGAGYGTNGTNACNYTNAARGGNTAYGAYGTNAARAAR GAYTCNGARAAYGAYCAYTGYGTNATHATHMGNTGYGTNACNCAYGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGGAYMGNYTNCAYGAYCAYTTYGARGAYCCNACNATHCAR ATGTCNTCNTGGAAYTTYGCNAAYMGNYTNCCNGGNCAYTGYAARGAYAARYTNGCNTCN ATHTCNAARTGYGCNYTNTCNYTNTAYGCNACNGTNGARGARATHTGYAAYYTNCCNACN MGNMGNGARMGNGARAARMGNACNATHAAYYTNTTYAAYGCNAGYTCNACNTTYGAYYTN GARYTNATGGARGGNYTNAARGTNATGATGYTNYTNCARYTNGTNGGNYTNMGNCARAAR ATGYTNGAYGGNGARGAYATHCCNATGTTYGGNCAYYTNYTNTTYGCNMGNGAYACNTCN GARACNGTNTCNGAYTTYATHAARAAYCAYYTNAAYTGYGTNGGNGAYTCNGGNGGNYTN GARCARGTNGARATGTGYYTNYTNGGNTAYACNYTNGGNATHAGYATHCARGTNYTNMGN YTNTCNCAYAGYGGNGARGARGAYTTYGARTGYTGYTTYCCNGAYGAYACNCCNGCNGAY ACNCCNCARGTNGTNYTNATHGCNGARGAYGAYMGNCAYTAYAAYGTNCCNYTNCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNTCNAGYATHGCNTCNGCN GTNTCNAARGTNGAYCARGGNGARGTNYTNGGNACNGGNACNAAYCAYGTNYTNAGYGCN CAYCAYYTNGARTCNMGNGAYGGNATGTTYAAYCAYMGNCAYAAYAGYYTNATGACNTTY YTNTCNGARCARGARGARGARAGYCCNGTNTCNGTNACNTTYCAYTTYGCNAAYACNAGY MGNATGATHCCNATHGGNATGGARCARTCNACNCCNTCNAAYAARCCNGTNACNGTNATH YTNTGGTGGTCNGGNACNCARCAYATHTAYCAYTAYTCNYTNYTNAAR---ACNAGYAAR GAYYTNGARTTYAARCCNGAYATHGTNTGGCCNTGYACNAAYGTNATHACNTGYTCNAGY ATHAGYCCNTGYGGNTCNCAYYTNGCNGTNGGNATGGAYAAYGGNAAYYTNGCNYTNTGG GAYTAYCARATGGGNYTNCCNAARTCNGTNYTNAGYGTNTCNAAYGAYTGYGGNGTNAAR GAYYTNMGNTTYYTNGAYCCNAGYYTNTTYCCNTCNGAYCCNCCNGARTAYCCNCCNTAY CCNGTNTCNTCNGCNACNTTYATHYTNGCNGARTGYTTYGAYGGNACNCARGCNYTNTTY GAYACNTGYGAYGGNAGYCARCARATHCCNMGNTCNATHGCNTCNATHCCNGARAAYGAY GAYGAYATHCARACNYTNYTNAARGTNATHCCNGAYYTNCCNGARYTNATGGTNTAYGTN AARAARAGYGGNTCNATGTTYATHAARGAYGTNGGNACNGGNGCNGCNYTNTGYCARATH TGYYTNCCNTCNACNCAYAGYATHCARACNCCNTGGAAYCCNGTNTTYGCNGTNGGNGCN GGNGGNCARGTNYTNTAYYTNAARGGNGARGGNACNGAYGTNAGYGARGAYGGNGARGTN AGYGAYATHTCNTGYYTNTTYAARTTYAAYYTNMGNGARTAYCCNGTNYTNGARGARTAY TGGGCNMGNCCNMGNGCNAARTCNTCNYTNATHGTNTAYACNACNCAYCARCARMGNYTN GAYTCNYTNATGAARGARMGNYTNCARCARCARGCNATGMGNAARCCNMGNATGCARAAR CAYTGGGGNCARYTNMGNGGNGARYTNGAYATHATHCARAAYGCNMGNGARGTNCARGTN GAYGCNYTNMGNYTNTCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGACNAAYAARYTNAARACNYTN GAYMGNTCNGARMGNGAYYTNTTYTCNYTNYTNAGYGCNGGNGTNMGNGARAGYCAYGAR AARGARMGNGCNMGNGCNGARMGNACNAARTAYTGGTCNATHATHGGNTCNGTNATHGGN GCNGTNATHGGNATHACNGGNTCNACNATHAAYAAYTAYAARMGNYTNAARGARATGMGN GCNATHGTNMGNGARTCNGGNGARAAYAGYGCNGARTAYAARCARATHGCNGAYAARGTN YTNGCNGGNYTNGCNTCNTCNTCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNCCNGCNTAYGCNACNCCNCCNGCNTCNYTN CAYMGNGTNGGNYTNGARTCNAGYTCNACNGGNTCNTCNTTYCCNGCNGAYTTYACNAAR CCNGTNCCNYTNGCNGTNGTNTCNCCNGAYGGNMGN------------------ACNAAY CCNTGGGGNAARCCNGCNCCNATHCAR------CCNTGYTCNYTNGARGAYGTNATGAGY GARCARYTNGCNACNGARYTNCARAAYAARGARGAYAAR---CAYGTNGAYCARGARYTN CARYTNCARGARGCNTCN---AARYTNAGYGARGCNACNGCNTCNTCNACNGAYACNGGN GGNTCNGAYGCNGARYTNGCNGCNAARYTNGCNGCNGAYGAYGTNGGNTAYGAYCCNAAY GAYGARATGATHGCNYTNATGYTNCARAARCARTAYGAYMGNGARTAYGAYTCNAGYYTN TCNAARAARGARCARAARTAYAAYGGNAAYAGYAARGTNTCNATHTCNTTYGAYAAYTAY AARMGNAARCAYATGCARTCNGARTAYCARAAYGGNGARGAYGAYGARGAYGAYGAYTTY TAYGARGARGARMGNCCNGAYCAYCCNAAYMGNACNCARTGGGAYAGYGGNGCNCCNACN ATHGGNGCNMGNGGNTAYAGYGGNMGNGGNAARAAYATHGTNACNAARCAYGAYAGYGTN ATHTGYGGNMGNMGNAAYGCNCARMGNYTNATGCARTTYCCNCCNGAYTTYGAYAGYGGN GAYGGNGARGGNATGGAYATGCARYTNCCNAAYGGNGTNTAYAAYAARYTNAARMGNCAY TCNCARACNGARAGYAARAARAGYCAYAARGTNCAYGARAARAARGAYCAYTCNACNGCN ATHAARGCNGTNGAYGARAARACNMGNATGYTNATHTTYAARATGGTNAAYTGYGARTAY YTNTCNTCNGTNGAYGGNGTNGTNAGYGARGGNAARGARGCNGTNGTNYTNAARGCNATH GGNGGNAARMGNGAYGAYGAYGARYTNCCNAARGAYGTNATHYTNAARGTNTAYAARACN TCNATGAAYGARTTYAARGCNMGNYTNMGNTAYATHCAYGGNGAYTAYMGNYTNTCNAAR GAYACNYTNMGNAARTTYAAYCCNMGNAARYTNATGMGNATGTGGGCNGARAARGARTAY YTNAAYYTNAARAARATGMGNMGNCARTGYGTNCCNTGYCCNAGYGTNYTNACNYTNMGN AARCAYATHYTNGTNATGTCNTGYATHGGNGGNGARAARCCNGCNCCNAARYTNMGNGAY GTNYTNTTYAGYGCNGARGAYTGYCARGAYGTNTAYGARCARACNGTNGAYATHATGAAR ATHATHTAYCAYAARTGYAAYATGGTNCAYGCNGAYTTYAGYCCNTAYAAYYTNYTNTGG CAYGAYGGNAARGTNTGGGTNATHGAYGTNGGNCARGCNGTNGAYMGNGARAAYTCNAAY TCNGCNTCNTTYYTNYTNMGNGAYTGYAARAAYGTNTGYGAYTTYTTYMGNCARMGNGGN GTNCAYAAYGTNCCNACNGCNGARAAYYTNTAYAAYGARATHACNAAYCAYACNYTNCAR GGNGARGGNAARGTNTTYGTNTCNGARGTNCARMGNTAYGARAARGARCARTAYGCNTTY GAYTAYTTYTTYGARCARTCNGARGAYGCNMGNYTNCARAARYTNGAYATHGAYAGYAGY AGYGARAGYGAYGARGAR---------------------------GAYMGNGTNCAYAGY MGNAAYATGATHYTNCARGARGARATHGAYMGNMGNTTYMGNTCNCCNAGYGAYAAYAAY AAYAARATHYTNGAYCARGTNATGGCNYTNMGNACNAARGARTTYCARAARTCNCARGCN CARAARGCNAGYCARATHCARCAYYTNGCNCARGARMGNCARMGNATHYTNGAYGCNMGN AAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CCNGCNACNGARYTNGAYGTN GGNATHACNGARTAYYTN---GGNACNCAYACNTCNTTYACNGCNATHATHAARCARMGN TAYTCNGAYTTYATHGTNAAYGARATHGAYYTNGAYGGNAAYGTNGTNCAYYTNACNAAR GTNACNCAYGAYGAYAARGARGAYGGNGARGARGARGARGARAARATGATHGARGTNGCN GAYAGYGTNYTNAGYGARGAYGAYMGNAARGCNATHCARAARATHGTNACNGAYMGNAAY MGNGAYGCNTCNCAYAAYATHAAYGCNCCNGARGAYAARGAYYTNMGNACNAARATHCAY YTNGCNGTNAARCARAGYTTYTCNCARYTNGARACNMGNACNGARGAYGAYGAYMGNGGN AAYAARGTNATHAARGTNATGTTYMGNAARGGNAARACNMGNGAYCARATHMGNGAYGAR TGGCCNAARTCNAARAARTCNTGYMGNTAYGTNAARTTYGTNYTNTAYAARGARAAYAAR GAYACNATGGAYGCNATHGGNYTNATHGCNAARAAYYTNMGNGTNMGNGARAGYATGTTY CARTAYGCNGGNACNAARGAYAARMGNGCNAARACNTCNCARGARATHACNGCNCAYMGN ATHCAYCCNAARAARYTNGTNGGNYTNAAYAARGTNYTNTGGAAYATGGGNYTNGGNGAY TTYMGNTAYGTNCARGARCCNYTNCARYTNGGNCARYTNTCNGGNAAYMGNTTYGTNATH GTNYTNMGNAAYGTNCARGGNAGYCARGARGTNGTNGAYTCNGCNYTNACNTCNYTNAAR GAYACNGGNTTYATHAAYTAYTTYGGNATGCARMGNTTYGGNACNACNTCNATHCCNACN CAYGAYATHGGNAGYGCNYTNYTNAARGGNGAYTTYGAYAARGCNATHGAYYTNATHYTN GCNCCNMGNAAYGAYGTNCCNGCNAARGAYAARTTYCARAARAARTGGGCNGARACNMGN GAYCCNGCNGCNACNYTNGAYYTNACNCCNMGNTTYTGYAAYYTNGARMGNAAYATHYTN GARGGNYTNATGAARMGNCAYAARTCNTTYAAYGCNYTNGARAARYTNCCNMGNAAYGCN MGNYTNYTNTAYYTNCAYAGYTAYCARTCNYTNGTNTGGAAYAARATGGCNTCNAARMGN YTNACNCARYTNGGNCAYAARGTNGTNGCNGGNGAYYTNGTNATGGARACNCARGGN--- ------------------GGNGTNACNACNAGYCCNATHGTNGTNACNGARGARAAYGCN GGNAGYTAYAARYTNACNGAYGTNGTNYTNCCNYTNCCNGGNCAYGAYGTNATHTAYCCN AAYAAYCCNGTNGGNGGNTGGTAYMGNGARGTNYTNACNTCNGAYGGNYTNGAYATHGAY AAYATGAARMGNCCNCARAARGAYTAYTCNYTNCCNGGNGCNTAYMGNCAYYTNATHGTN ATHCCNAARGAYGTNTCNTGGACNCAYCAYAGYTAYAAYGAYTAYACNAARCCNYTNACN YTNAGYGAYYTNGAYYTNGTNCARGGNAAYACNYTNGARGAY---AAYGGNGARACNGGN AARATGTCNGCNGTNGTNYTNAARATGTCNYTNCCNACNTCNTGYTAYGCNACNATGGCN YTNMGNGARGCNACNMGNGTNGAYACNTCNTCNTTYCAYCARACNTCNYTNAAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGGCNGAYGARYTNCCNATHTTYCCNAAR GCNTCNTCNATGTAYYTNCAYAGYGGNAAYATGATHAAYTGGAAYMGNYTNAARMGNAAR CCNAAYYTNTCNTCNTCNGAYGARYTNTGYGARGTNATHACNCARACNYTNAGYTCNTAY YTNGARGARGCNAAYAARACNGARYTNCARTAYGTNACNGARGTNTAYAARATHAAYACN GARAAYGTNGARYTNATHGAYGARAGYGARMGNGGNGAYGTNAARATHACNGTNAARGTN TTYATHTGYGAYTCNCARTCNCCNAAYGTNATHGCNGAYGCNGTNAGYMGNGTNYTNAAY GARYTNGGNACNACNTTYATHGARACNYTNYTNYTNGCNGTNAGYCCNAAYGGNCARGAR GARCARGARACNGARGARGTNGTNAGYYTNTCNACNATHCARMGNTAYTGGCARGCNATG GARGARYTNGTNGCNAARGAYAARGTNATHTCNYTNGGNGTNTGYGAYYTNGGNAARGAY GGNYTNGARGCNYTNTAYAAYTGGGCNCARGTNAARCCNGTNGTNAAYCARGTNAAYYTN GARTCNTGYTGYGTNYTNCCNAARGARYTNACNGARTAYGCNAARGCNATHAAYATHCAR YTNYTNACNCAYAAYGAYAGYCCNGCNTTYGTNACNAARGARYTNYTNCARGARAARATH CARAGYGTNTCNACNGARMGNGAYAGYGAYGCNTGGACNCCNGARTGGGTNGTNMGNTAY TCNGGNATHYTNAARAAYMGNGGNATHATHAARATGAARGGNTAYGTNTTYCAYGCNACN MGNGAYAAYAARAARMGNATHYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MGNTCNCCNTCN CCNGARCCNATHTAYAAYAAYGARGGNAARMGNYTNAAYACNMGNGARTAYMGNACNMGN AARAARYTNGARGARGARMGNCAYMGNYTNATHCARGARGCNYTNAARYTNAAYACNGAY TTYAARCCNCCNAGYGAYTAYAARCCNCCNGTNGTNMGNGTNAAYGAYAARGTNATGATH CCNCARGARGARCAYCCNGAYATHAAYTTYGTNGGNYTNYTNATHGGNCCNMGNGGNAAY ACNYTNAARACNYTNGARAARGAYACNGGNGCNAARATHATHATHMGNGGNAARGGNTCN GTNAARGAYGGNAARATHGGNMGNAARGAYGGNCARCCNYTNCCNGGNGARGAYGARCCN YTNCAYGCNTAYGTNACNGCNAAYAAYCCNGARAAYGTNAARAARGCNGTNGARAARATH AARGAYATHATHAARCARGGNATHGARGTNCCNGARGGNCARAAYGAYYTNMGNMGNCAR CARYTNMGNGARYTNGCNYTNYTNAAYGGNACNYTNMGNGARAAYGAYGGNYTNTCNAAR YTNMGNCARATHGCNGARAGYCARACNATHGTNACNAAYACNATHATHTGYACNGTNTGY GGNGGNACNGGNCAYATHGCNCARGAYTGYAARCARAARMGNCCNGGNGAYACNTTYMGN ATGCARCARATGCARAAYCCNGCNGAYMGNGCNAARATGGAYAGYGARTAYATGTCNYTN ATGGCNGARYTNGGNGARGGNCCNCCNCCNCCNAARAAYGARACNGCN------CCNAAY ---------------AGYCARCCNCCNTTYAGYMGNCCNYTNYTNACNAAYCCNCCNCCN AAYCCNATGGCNATHAAYTCNCCNTGGCARATGCCNCCN---AAYMGNCCNCCNATGTCN GCNCCNGTNCCNCCNCCNCCNAGYTCN---GGNCCNCCNYTNYTNAAYMGNCCNCCNATG GGNATGCARTCNACNGCNCCNCARATHAAYCCNATGGGNMGNYTNCCNATGCCNYTNATG TCNACNCCNGTNCARCCNCCNCCNGGNATGCARGCNTCNCCNGCNYTNYTNCCNCCNCCN ---------------------------CCNGGNCARCARCCNCCNCCNCARCARATGGGN GGNATG---CARCARCCNCCNCCNCARCARCARCARCAYCCN------------------ ------CAYCCNCARCARCARCARCARCCNYTNCARCARGCNGCNAGYCARTCNCARCCN ATGATGAGYATGAAYCARGTNTCNTCNAGYGCNGGNATGGGNATHCCNCCNCCNCCNTCN TCNATGATGAAYCCNCCNCCNCCNCCNCCNGTNAGYACNCARGGNCAR---GTN---CAR CARACNCCNCCNTGGATGCARCARCARCARCARCARCCNGGNAAYATGGGNYTNCARCAR CARCCNCCNCCNCCNCCNCCN---------ACNTCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TAYATHTGYGARGARCARAARMGNGAYACNAARGCNACNGCNGGNGCNTGYATGCAR TGYAAYMGNAAYGGNTGYAARCARTAYTTYCAYGTNACNTGYGCNCARGCNCARGGNYTN YTNTGYGARGTNACNGGNAGYTAYGARAAYGTNAARTAYTGYGGNTAYTGYTCNCAYCAY TAYAARAARYTNAARCAYYTNTCNAAYGTNAARACNATHCCNGCNTTYMGNCCNATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GCNATGMGNTTYYTNATHTGYTTYGTNCARGARGTNCARAGYAAYAAR ATGYTNTAYTGGCCNYTNTTYGTNYTNAARACNTCNATGGTNGGNTTYTCNTCNGTNGTN TCNGTNTAYACNGGNTAYAAYGTNATHATGGARCAYGGNATHGTNACNAGYYTNTTYYTN TGYTAYCCNGCNGTNATHTAYYTNYTNTTYTTYGGNYTNGCNATHAARCCNYTNTAYCAR MGNCAYCARGCNTGGCCNMGNCCNGCNTAYGGNATHGAYMGNCCNGCNGGNCCNACNMGN ATHAARATGAARGAYGAYGCNCCNYTNTGYCAYACNTGYACNYTNACNCCNGAYATHGTN MGNGARGARGTNGAYATHYTNAARMGNGAYTTYAAYACNMGNYTNCARCARATHYTNTTY AAYTCNYTNATHACNTCNTTYTAYGCNACNGGNGTNCCNGTNTGGTTYTCNCARATGAAY ACNYTNTAYTAYGAYTCNTGGTGGATGTGGCARCAYGTNTCNYTNTGYTGGYTNAGYGCN YTNYTNATGYTNACNGCNCAYTTYYTNCCNCCNAAYTAYYTNCAYYTNYTNCAYAARAGY GCNMGNCAYYTNGGNMGNTGGCARMGNATGGARGCNMGNCAYGCNCAYGTNCCNTAYAAY GCNTGGTCNGARYTNCARGTNTGGCCNCARGGNGCNYTNGTNAARCAYGTNMGNGGNYTN TTYAARGCNGARGGNATHAAYGTNACNGCNGARCCNGGNAAYAGYYTNCAYAGYMGNTTY TTYYTNYTNTTYCAYCARCCNATGMGNGTNATGAAYTGGYTNGTNTTYYTNACNTGYATH GTNATGGCNTAYCARGCNTTYMGNYTNGTNCARAGYTCNGARTGGAGYCAYATHATHTCN YTNGCNYTNYTNATGTTYTGYAAYTTYTAYACNYTNTTYAARYTNATGMGNGAYTGGTTY ATHATGGGNAARATHTAYAARGAYCAYGAYTAYGTNGTNTCNAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TAYATGYTNTCNTGGATGGARMGNAARYTNGCNTCNGCN YTNTTYGCNACNCCNCCNACNGCNACNYTNGARGARGCNYTNAARCAYYTNYTNAARGCN GARAGYYTNAGYCCNYTNTCNTCNATHCARAAYGTNYTNTAYYTNTCNAARGCNTAYATH GCNAARGGNGAYTAYTGYGCNGCNGTNGARTAYYTNAARGCNGGNATGGCNYTNAAYTGY TCNTTYYTNGAYGAYMGNAARGCNYTNGARAARATHGARAARYTNTAYAARCARTAYAAR TCNTAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GARGTNTAYGAYGAYGCNTTYTCNYTN TCNGARAAYYTNTCNYTNTAYGAYTGGTAYCAYGCNGAYATHGAYMGNAAYGARGGNGAR AARMGNGTNAARGCNGTNGGNAARTGYGGNACNTTYYTNATHMGNGCNAGYGCNGTNAAY GAR---------TAYCCNTAYACNYTNGTNGTNAARACNAARAAYGARGTNAARAAYYTN MGNATHMGNCARMGNCCNGAYAAYAAYTAYGCNGTNGGNACNACNGARMGNGCNGAYGAR YTNMGNTTYCARACNYTNCARGARYTNGTNCARCAYCAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNGTNGTNMGNGGNGCNATHACNMGNCCNTGG TCNCCNAARTTYCCNGGNGAYACNCCNMGNMGNAAYAARTAYYTNMGNAARGCNGARAAR YTNAAYCCNGAYTCNCARTCNTAYTTYAAYGTNGAYAGYTTYAAYCAYCCNTGYATHYTN GAYTTYTAYGAYMGNATGYTNTTYACNYTNYTNGTNCCNCAYACNATHACNGARATHAAY YTNACNCCNGAYAARCCNTGYAARACNCARCARGAYCCNGARYTNTCNGARTCNMGNYTN TCNTCNCAY------------------------GGNTCNYTNGTNAGYTCNGCN---GCN CARAGYCAYGAYCCNTTYMGNTGYGGNACNCCNTCNATHAAYAARAAYGCNATGTCNACN MGNMGNMGNYTNGAYTAYGGNGARGCNGTNMGNAARCAYAAYGCNMGNCCNAARACNGCN TCNGARTAYATGGCNGTNYTNGARAARGARMGNAARYTNMGNCARGARGCNTCNACNMGN GTNCARTCNGCNAGYTTYCARAGYAGYAARATGTCNGCNGGNAAYMGNAGYGCNAGYCAR TCNGCNGCNACNAAYGCNACN------AGYMGNCCNACNAARACNMGNAGYACNMGNGAY TTYGTNTTYGARGCNCCNACNAAYTAYTCNATHCCNGTNTTYCARCCNATGAAYATHGCN GARGCNCCNMGNATGTAYTAYMGNCCNTGGACNGGNGAYAARYTNCCNGTNGGNAAYGTN CCNCAYCCNYTNCCNTCNCCNGCNTTYTAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TCNGGNTAYMGNTAYACN GARGGNAARYTNYTNCAYACNGGNATGGCNGCNYTNACNGCNGARAGYAGYCARGCNAAR ACNTAYYTNTTYGARGGNYTNGTNGGNAARGAYMGNTCNMGNGTNTGGGAYCAYATGCAR TTYTGGGARGAYATGTTYYTNGAYGCNGTNGCNCARGARMGNGAYATHATHGGNATGGAY CARMGNCCNTCNGARATGATGGARMGNTAYGARTCNYTNGGNGAYYTNGARMGNAARMGN YTNGARYTNGAYGARGAYGTNGTNYTNTCNACNATGYTNTAYAAYCARTCNGCNTTYATG YTNATGATGMGNGTNCCNAARCARGARATHAARAARAARGTNMGNMGNYTNATGGGNAAR TCNCAYATHGGNYTNGCNCAYAGYCARGARATHAAYAAYYTNYTNGAYAAYATHACNAAY YTNCARMGNCARAAR--------------------------------------------- ---------------------------------YTNAAYATGGGNCARCAYACNTCNMGN CARGAYATHATHCAYAAYGARGTNAGYGAYYTNMGNATGMGNAAYTGGYTNTGYGGNAAY GTNGCNATGMGNGARTCNTCNAARGCNYTNGCNGTNTGYYTNCAYGAYAARATHTCNCAR ATHCAYAARGARATGTCNMGNGCNGTNGGNMGNGGNYTNGTNTGYAAYMGNAAYTGYAGY CARAAYCARACNGAYTGGTGYTCNGTNTGYGTNMGNTGGTCNMGNGARATHATHGCNATH TGYGARCCNGAYTAYMGNCCNMGNATHAARTGGTCNMGNYTNAAYTCNTCNCARTGGTCN GTNAAYCCNTAYGARGTNGCNMGNGCNYTNATHCCNAARGCNCAYMGNYTNTAYTAYAAR TGYTCNGARTTYCAYGARGAYTTYMGNTTYAGYYTNAGYTTYATHGARAAYTGYATHGAY ATHCCNGTNTCNMGNTCNATHTGYGARAARTCNTGGCARTTYMGNAGYMGNYTNAARMGN AARAAYGGNATHATGMGNATGGGNTGYMGNGARYTNGARGARGGNACNTCNYTNATGATH TCNYTNGTNTCNATHCCNGCNYTNGGNGGNAAYGARAGYACNGTNGARAARYTNAARACN YTNGCNAAYGAYYTNGAYGARTCNAAYGGNGGNTGYTGYGTNATGCARGARYTNMGNGCN MGNGAYATHGCNATGGARYTNAGYTTYCCNGTNYTNACNTTYGCNTCNGGNCCNACNAAY AGYATGMGNGGNGCNGCNTTYYTNACNGCNAARACNGARGCNGTNGTNGTNGAYATHGGN GGNACNACNAGYGAYGTNGGNATHYTNAARATGGGNTTYCCNMGNGARTCNGCNACNCAY GTNCAYGTNGCNGGNGTNAARACNAAYTTYMGNATGCCNGAYGTNATHAGYATHGGNYTN GGNGGNGGNTCNTAYGTNGTNGARAARMGNGGNGARGAYGGNGGNYTNYTNGGNATGCAR ATHGGNCCNYTNAGYGCNGGNTTYAAYYTNCAYMGNGARGCNYTNGTNTAYAAYGARGAR GAYAGYACNGARGGNMGNGTNYTNACNGCNACNGAYATHGCNGTNTGYTCNGGNYTNTGY AAYYTNGGNTCNAARGARMGNGTNAAYCAYYTNGCNCCNAAYGTNGTNAGYGARTCNGTN GAYGARATHCAYAARATGYTNGARAAYYTNGTNGAYMGNATHAARYTNAGYAARGAYGAR GTNCCNATHATHATHGTNGGNGGNGGNAGYGTNYTNGTNGAYACNAARMGNCCNTTYMGN GGNGCNTCNGARYTNATHATHCCNAARCAYTTYGGNGTNGCNAAYGCNATHGGNGCNGCN YTNAGYAARGTNTCNTCNAGYGTNAAYTCNGTNGTNAAYYTNYTNAAYYTNGTNGAYATH GARGCNATGGAYAGYGCNGTNAGYGAYGCNAARATGAAYGTNGAYTCNGGNAGYGAYMGN GAYYTNGAYATHGCNGTNGARAAYGCNAARACNCCNTTYYTNAARAAYGCNMGNGARGAY GCNATHGCNAGYTGYTGYGARCARGCNAARTCNCARGTNATHAARYTNGGNGCNMGNAAR GAYAGYATHGAYATHYTNGARMGNTCNGAYTCNYTNATHGCNTAYATHGCNGGNMGNGTN YTNAAYATHAARGTNAARGTNGTNGGNGAYATGAAYCARCCNGCNACNACNGGNGARGGN GTNACNCAYTGGACNGARCCNAARGGNYTNYTNGGN---ATGYTNGARAAYAARGAYCAR TCNAAYACNAARCARAAYGTNACNTCNACNGGNGTNAARYTNTCN--------------- ---GAYAAYGAYTCNGTNYTNTGYCCNAARGARCCNTTYATHGAYACNAAYACNGGNGAR TGGATHYTNTCNGAYTGGGAYATHGARTGYATHGCNATHGGNTCNAGYATHTAYGGNTGY GGNGGNGGNGGNAGYCAYTAYATGGGNAARYTNMGNGCNYTNMGNGCNYTNMGNGARGGN MGNGARTTYMGNGTNATHTGYGCNAARMGNYTNYTNGCNAAYGCNGAYCCNCARAARGAY YTNATHTTYACNCCNGGNGTNATGGGNACNCCNACNGCNGTNTGYGARCARGGNGTNTCN ATHYTNGARTCNGARGARGCNTTYMGNTGYYTNAARGAYATHTAYGARATHGGNMGNTTY GARGARGARCAYYTNCARAAYACNGAYGGNGTNACNGTNGARGARAAYGARGCNGGNAGY MGNTAYATHTCNAAYTAYAARCCNGTNCCNYTNGAYAARAARGARGAYTAYAARATHGTN GGNATHATGGCNGTNGARTTYGCNGGNATHAAYGCNYTNGARCCNYTNYTNYTNGCNTCN AAYYTNAAYATHCCNGTNATHGAYGCNGAYGGNATGAGYMGNGCNTTYCCNAARGTNGAR CARTTYATHCCNTTYATHTAYGGNAARTCNCCNTAYCCNGGNTCNGCNGTNGGNATHGGN AAYACNTCNGARMGNGCNGTNYTNYTNTAYGCNCCNCARAGYAARCARTTYGARGARTAY TTYMGNGAYATHGTNATHAARAAYGGNTGYTAYGCNCAYYTNATGATGTCNYTNACNAAR TCNGARGTNYTNACNAARACNGTNCCNCAYGTNGTNAGYAGYGCNTGGMGNYTNGGNGAY GTNGTNYTNMGNGCNMGNYTNCARAARCARCCNGTNGTNGAYGCNATHGCNGARCARGAR AAYGGNGARCAYGTNATHTCNGGNAARGTNGTNGAYGTNMGNCARGARACNAGYGGNGGN TTYAAYAARGGNCAYGTNACNGTNGARGGNACNGAYGARTGGGCNGGNCARGCNGTNGTN ATHGARTTYCARAAYGARTTYYTNGTNATHTTYCCNYTNGTNGAYGGNAARCAYGGNCCN AAYAARGCNTGYGTNCCNGAYYTNATHACNGTNGTNGAYTCNGAYACNGGNGARCCNATH CAYGCNGARGARATHMGNTAYGGNATGMGNATHGCNGTNATHATHATHCCNTGYTGYGAY YTNYTNMGNCAYCCNGARGCNYTNAARTGGGTNGGNCCNACNGCNTTYAAYTAYCCNCAR GAYGTNTCNTTYGTNCCNTTYMGNGARMGNAARCCNGTNCARCCNATHCCNCCN---ATG GARCARCARYTNGCNAGYYTNCARMGNGAYAGYYTNGGNCCNMGNAGYYTNGGNAGYACN ACNTCNGAYAGYTCNGAYACNTTYCCNGCNTCNTCNGCNAGYAGYTCNGAYATHCCNGAY GGNCCNAAYCARCCNCCNTCNTCNAGYCCNCCNGCNATHCCNGTNCCNACNGARATHAGY AAYCARYTNGCNACNYTNAARTCNGAYYTNYTNGTNYTNMGNMGNCARACNCARYTNAAY GTNGARGCNATGMGNGARGARTTYYTNAARGCNGCNAAYTCNATHAARGTNGTNTTYTCN TCNGTNCCNGGNGCNGARAAYCARYTNAGYTTYCAYAAYMGNGTNGCNGCNACNAARACN AARACNACNTAYGTNAGYGAYAARGTNCARGTNGAYCARGARYTNAGYGAYYTNGARAGY AGYGTNGARGARYTNMGNAAYGAYATHATHAAYCAYCARTGYMGNGTNCARYTNTCNGAY GTNGARGGNATGGCNYTNYTNYTNAGYAAYATHACNAARAAYYTNGCNGAYYTNAARACN CARTTYCCNGARGTNCAYGARCARATGAARGARGTNATGAGYAGYGARATGCARCARGTN GTNGCNGARGARAAYTTYYTNAARGARGARCCNGCNAARATHGARAARTCNYTNATGMGN TGYAARAARYTNACNGGNACNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNCCNMGNYTNAARMGNAARGARAGYACNGGNMGNAAYGARTTY GCNACNATHMGNGAYYTNTTYCARTAYGTNATHGAYGARGAYAARAARGARAARYTNYTN AARGCNGARAARGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AAYGTNCARGAYACNGARYTNTTYGTNCCNGGNGCNTCNAARCARACN YTNGAYAAYYTNGCNAARGARACNGCNMGNYTNMGNAGYYTNYTNAARCARGARAAYGGN CAYYTNGGNAARAARTCNGCNGAYGARATHGARGAYATGAARACNGCNYTNGARGARGTN GARYTNGARAAYAAYAAYYTNMGNAGYAARYTNMGNGARATGGARTCNTTYAARYTNAAR YTNGTNAGYGAYTAYGARATGATHGTNAARYTNAAYAARGARAARAAYGCNTAYAARGGN MGNYTNCARYTNYTNGARGAYAARGARTTYGARACNGARAARATHTCNTCNAGYGAYATH CARGARYTNAARGAYYTNYTNAARCARACNGTNCARAARTGYAGYCARYTNAAYGTNCAR YTNATHGAYGTNGCNAGYGAYCCNAGYACNCARGAYAAYMGNTGGGAYGARACNGCNMGN GTNCCNGGNGTNTCNCARCARGARTAYAAYMGNYTNCARGARAARYTNCARGARGCNGTN ACNATGAAYCARAARTGGCARATGTAYAGYAARGARMGNGAYMGNCARATHCARACNYTN AAYGAYCARYTNCARGARCAYCARGAYCCNACNCARATGTCNGCNATGATHGARATGGCN GARAARAARAAYGCNGARTAYGTNAAY------------GARYTNAAYMGNAARGAYGCN GARATHGTNGARCAYMGNAARCARATHTGYGGNYTNTCNAARGARYTNACNGAYGTNMGN CARYTNAARGARCARTAYTGYCAYGARAAYAGYACNGTNGARATHYTNCARCARCARATH CARGTNTGYACNGARGAYTTYAAYACNGARMGNAARGAYMGNGARGCNGCNGTNCARAAR GCNMGNGCNYTNCARGARGARAAYGARMGNYTNATHMGNGARAARACNAAYYTNAARGCN CARGTNGARCARATGAARMGNGTNGCNGARCAYCAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TGYCAY CARTGY---------CARTAYGCNACNTGYGCNGAYAARTAY------------GTNGCN GAYCCNAAYAAYYTNGGNGAYTGYGGNGAYGGNTAYTAYTGYGTNAARTAYAARACNATH GTNTGGATHGGNGAYTCNGGNGARATHAARGGNAGYTAYAARGARTCNTCNGTNGTNACN MGNACNTGYGARACNAARAARGGNCARACNGARGGNTGYACNGGNTGGCARAAYAAYGGN GGNGTNACNYTNAARTGYTGGTGYGGNACNGAYGGNTGYAAYAGYGGNMGNTCNYTNAAR CCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AGYGCNGCNACNTCNGARATHAGYAGYYTNAGYGGN--- ------------------CARGAYGTNAARCCNAGYCARAARATGYTNGAYCAR------ ------------------CARTAYAARAARAAYTTYGGNGCNCCNGGNTCNAGYTCNAGY AARTCNAARGGNTTYYTNTCNACNAGYCARGARATHTAYTCNTGGAARYTNAARAARATH AARMGNACNATHGARGAYATHATHTTYGTNAAYGGNGCNGTNTGYGAYGARGTNGTNMGN ACNGARGARAARYTNGCNAARGTNAARGARGARMGNMGNTTYYTNYTNMGNAARYTNYTN CARTAYCARTCNYTNAAYGARTCNTCNGGNGCNTCNGGNAARGCNGAYGCNCCNTCNTCN GCNGTNGTNMGNAGYYTNAARGCNTCNGCNCARYTNGAYGGNTCNGCNGGNAAYGAYGCN CCNGTNAARCCNAARGCNGCNAARMGNAARYTNAAYGCNTCNTCNTCNGCNGGNGCNGGN CARACNGCNGCNGGNGTNGGNACNAAYGCNGCNTCNTCNYTNGCNGCNTCNTCNGCNTCN TCNGAYAARAARAARAARCARCCNCARTCNGCNAARGAYATHYTNGAYTCNYTNCARGGN MGNCCNAARAARNNNAARTCNGCNGGNAARAARACNATHCCNCCNYTNATGYTNGAYTCN YTNGGNMGNCCNATGATHCCNATGATGYTNGGNGAYATHACNYTNCAYAGYATGGGNGAR ATHGTNACNGAYMGNYTNAGYTTYCAYTGYGCNGARGCNATHTTYCCNGCNGGNTAYTGY ATHACNMGNATHTAYGTNAGYYTNCAYAARCCNGAYGCNAARTGYYTNTAYACNTGYAAR ATHTCNGARGGNGAYGARGAYGCNYTNTTYGARATHGCNCCNGARGAYAGYTCNGAYATH GTNTTYMGNGCNACNTCNCCNGCNGARTGYCAYAGYYTNYTNYTNMGNGCNGTNAAYAAR TCNMGNGGNGCNGARGTNGTNCCNGTNGARACNGAYGGNYTNGAYTTYTTYGGNYTNTCN CAYGCNGTNGTNCARAAYYTNATHCARTCNATHCCNGGNGCNMGNAARTGYTCNMGNTAY AARTGGGTNAARTTYGARATHGAYAARACNGARACNAAYGARAAYTTYTCNGTNGGNMGN GCNGAYCCNMGNATHAAYTAYGAYGCNTTYATHACNCAYATGACNGCNGTNATHCARGCN MGNGCNGGN---YTNGCNTCNCARGTNGARAARTCNACNAGYYTNMGNTCNYTNYTNACN AAR---------ATGAAYTTYAAYATHGARAARGCNYTNGCNTCNGGNGGNMGNYTNGGN AARATHACNCARATHGCNCAYGGNMGNACNYTNTCNYTNGARACNCCNATGTGYACNYTN TTYACNAARGGNGGNAGYGTNCCNTAYYTNAGYYTNAGYATGYTNGARAARATHAARCAY ATHCCNGARGTNGCNACNATGAGYATHAAYGCNTTYATHGAYCAYATHGAYAAYATHCAR GARAAYGGNAARGGNYTNAGYGGNTTYACNTCNATGAARAAYAARYTNGTNTTYTCNTCN YTNCAYGAYGCNAGYYTNCCNGTNCCNACNGGNAARAAYGAYAARTCNGGNGTNGCNGTN TGGGGNAARGGNGGNAARGCNATGYTNTAYCCNGGNCARTAYATGAARATGCARGARTCN ATHMGNCCNGAYTGGYTNATGGCNYTNAGYGAYGGNGAYACNGAYGGNGAYAGYACNGAR AARMGNGCNGGNAARGCNGTNGAYMGNACNYTNGAYTTYYTNGAYACNATGGTNGCNGGN TGGGARAARAGYGTNGTNYTNAARAAYACNAGYYTNATHGGNGTNATHGTNGGNGGNTTY AGYGARMGNCARMGNCARMGNAGYGCNAARGARACNTCNACNMGNCCNGTNCAYGGNTTY YTNYTNGGNGGNTTYCARAARGGNAAYACNGARGARAAYATHTTYGARAAYGAYTCNTTY AARAARATHYTNYTNAARACNYTNAGYAAYYTNCCNGARACNAARCCNMGNYTNATGGAR ACNCCNTGGTCNCCNYTNCARGTNATHCARGCNTTYAARYTNGGNATHGAYGTNTTYTCN AGYGCNTAYCCNCAYACNYTNGCNGARAARGGNGTNGCNATGACNGARGAYTTYAARYTN CCNCCNACNTCNCARACNGCNGGNYTNGARAARGARGARGGNGTNAGYGTNACNGAYTGY GGNCAYTCNGTNATHAAYATHAARGAYAARMGNTAYTTYGARGAYTTYGGNCCNGTNYTN GAYGGNTGYCARTGYTAYACNTGYGCNACNTTYACNMGNTCNTAYATHCAYCAYYTNYTN AAYACNTCNGARYTNYTNGCNCAYGTNYTNYTNACNATHCAYAAYTTYGARMGNTAYTTY CAYTTYTTYCAYGCNATGMGNAGYGCNYTNMGNGAYGAYMGNYTNGAYGARYTNGARAAR AARYTNTCNCARCAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GAYCAYTAYCAYCARATGAARGTNGGNATGGCNGGNCCNAARGCNAGYAAR CCNGAYAARTCNYTNGAYGTNGTNCARGGNTCNATGGTNGARGAYYTNGTNGTNYTNYTN CARTCNTTYAARGARAGYGTNTCNAAYATHTAYAARCAYGGNAGYGCNAARACNACNTCN GAYGGNGGNGARACNTCNAARCCNGCNGARAGYATHYTNAGYAARMGNCARGCNATHAAR ------------------------------------------------------------ ------------------------------------------------------------ ATGTCNACNGTNTGYAAYTGGYTNAAYATHTTYTGYYTNMGNGARGTNCAYAAYAARAAR GCNGTNCARCAYMGNATHCAYCCNAAYMGNCARGCNTAYGAYGCNGTNGTNGTNTGGAAY GGNAARGARAAYCARAARTCNAARMGNGCNAGYATHAGYTTYGAYGTNATHYTNAARCCN GCNTCNGCNGAYTCNCCNMGNCCNTCNYTNCCNCARTCNCCNMGNGAYAAYAARCARAAR GARYTNTCNGARGARAARATHGCNATGAARYTNAARAARGCNGARCARMGNMGNAGYYTN ATHGARCARGARAARYTNGARCARYTNGCNAARGARMGNCARAARTAYATHGARGTNATH ACNAARGCNCARTCNGARAGYCARGARTTYATHAARAARACNGARGARAARYTNAARMGN TCNATGGARAGYMGNMGNGARAARMGNGARACNCARATHMGNGCNYTNCARGARMGNYTN MGNGARCAYTCNGTNAARGTNCAYGAYGTNCARAARACNGGNATGGARATGGTNAARGAR TTYGARGCNAARGCNGARCARAARYTNACNCARAARATGACNGCNTAYGARGARAAYMGN AARAAYCARYTNTGYATHACNYTNGCNAARYTNCARGARCAYGCNAGYCAYATHAAYGAR GTNTGYYTNGCNAGYGARAAYMGNGGNCCNAGYACNGAYGARYTNCARGARCARYTNGTN YTNAARATGGARAAYGCNYTNAARAAYMGNGARGARCARYTNMGNGGNATHCARGAYMGN YTNGCNGARCAYGARAAYMGNATHAARGARGTNCARAARAARAARGGNATGGTNTCNTCN GGNGARCCNYTNMGNTAYAAYTGYCAYATHTGYTTYGCNAARYTNAGYACNGARTTYTTY YTNMGNTAYCAYYTNGCNAARCAYMGNGGNTTYCCNCAYATGTCNACNYTNTCNACNTCN GAYGGNGTNYTNATHTGYGCNCAYTGYGGNTAYATHGCNAARAGYAAYACNGAYYTNGCN AAYCAYGTNGCNACNCAYGTNACNGAYMGNMGNTAYAARTGYTCNCARTGYGAYTGGGAR GAYCAYCAYAARAARTCNATHCARTCNCAYATHAARAARMGNCAYGGNCARGAYAGYGAY GCNMGNGTNTTYGAYMGNGARAARAARMGNGGN---AARATGAARYTNAARGTNGTNAAY YTNAAYCCNTCNGTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TAYACNAAYMGNYTNCCNYTNGAYTGYCCN YTNTCNMGNYTNGCNACNATHTGYAARATHTCNCCNTCNTTYGARGTNCCNGARYTNAAR ACNGCNGCNATGTAYAARATHACNGCNGGNATHACNTGYCARAAYGTNGTNTCNGTNTTY TTYCARGTNCARAAYGAYCCNCCNYTNGAYGAYGTNMGNAGYYTNTGYYTNACNTTYATG GCNACNCAYYTNAARGAYATGTCNAARGARGCNTCNTTYGARAARYTNCCNCARAGYGTN ATHGTNTCNGTNGTNCARGARGCNACNATGTCNYTNTGYYTNAAYGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHTCNACNTCNYTNCCNYTNCARGTNCCNGTNTCNCCNCCN CCNGCNGARYTNAAYYTNTAYCCNCAYATHCAYGGNYTNCCNCCNCARMGNTAYATGTAY GGNYTNCCNCCNCCNYTNYTNCCNTCNATHAARYTNCCNTTYAARYTNGAYTTYGAYGAY CCNGCNAGYATHCAYGAYCAYYTNTAYCAYGCNTAYAGYGAYTGGGAYAAYCCNMGNCCN GGNTCNYTNGCNGCNCARCAYCARCAYCARTCNCAY---MGNYTNTCNGGNYTNACNTCN GARYTNYTNCCNCCNGCNCCNGTNGTNGAYGCNGTNCCNGCNTTYAGYTTYGARGCNYTN AGYYTNACNACNCAYAGYACNCARACNYTNACNAAYACNAGYAGYGCNTTYAARTCNATH ACNGGNAARAGY---GGNGARAGYTTYGTNTCNAAYGTNAAYMGNTGYGGNGCNGARGGN AGYTCNGTNGAYCCNACNACNAARCCNYTNGAYTTYTCNTCNTTYYTNAARATHCCNCAR GCNTGYYTNAAYTCNTCNTCNTCNTCNYTNCCNYTNTTYACNTCNTCNGTNCCNTCNGCN GTNCCNTCNTCNGTNGTNTCNAAYYTNCCNGTNACNACNTCNGTNACNGCNTCNAARAAY MGNTCNTGYCAYGGNCCNCCNTCNTCNMGNCCNGTNCCNYTNGGNGGNAAYGTNGCNAAY TCNAARTGGGARAARACNCAYTCNYTNCARTGYAARAARTTYACNGCNACNGCNCCNAAY AARTTYGCNYTNYTNAAYCARCARGGNGAYACNGTNAAYCCNTTYTCNGCNGTNGCNAAY CCNGTNCCNCARAGYAARTCNYTNMGNTCNACNYTNCCNTGYYTNCAYTCNTCNTCNCCN ATHAARGCNAGYGAYGCNAAYTCNYTNCCNACNTCNTGYCCNAAYGGNAAYGTNCCNTCN ACNATHGTNAAYAAYATHGGNGTNGGNACNACNACNCCNTGYGTNGAYGTNGARTGYAAR GTNCAYCAYGAYGAYAAYTGYGAYAGYGTNGAYGAYAGYTGYTCNGARMGNAGYTCNAGY ACNTCNTCNAAYCARAARGARGGNAARTAYTGYGAYTGYTGYTAYTGYGARTTYTTYGGN CAYAAYAAYCCNCARGGNCCNAARACNAGYCCNAAYTAYYTNGARATHAARGAYMGNYTN MGNAARAARYTNAARAARAARAAYGARAGYAARCCNAARTCNGCNAGYCCNCCNCAYATH GARGGNAARMGNGARGARYTNTCNAARGCNACNATGGARAARMGNGGNYTNGAYGARYTN YTNAAYTTYATHAAYGGNACNGAYGARAGYACNMGNACNAAYAARGCNGCNAARMGNGCN MGNCARAARCARMGNAARYTNGARGARAARGCNMGNCARGGNAAYGGNGCNCARAARTGY GARGARAAYMGNCARCCNGARGTNACNAARTCNYTNACNAAYYTNYTNCAYAARCCNCCN YTNGGNYTNAAYAGYYTNGARCARCARCARGCNMGNYTNGAYAAR---GCNCCNCCNACN GGNCARGARMGNATHAARGARYTNCAYAARAARYTNGCNYTNYTNAARGARGARATGAAR CARGARACNACNMGNTCNCCNATGATHATHGARTCNACNMGNCCNACNATHGTNTCNTCN AARGCNCCNAGYGCNACNGTNAAYCARYTNAGYTCNTCNAARGCNCCNGGNTCNGCNAAY GGNYTNATHTCNATHAARCCNAGYAAYGCNCCNGGNGCNTCNATHGGNYTNAGYTTYTCN GCNCCNAGYGCNTCNAAYGGNYTNAGYTCNTCNAARACNCCNAGYGCNTCNAAYGGNYTN AGYTCNTCNAARACNCCNAGYGCNTCNAAYGGNYTNAGYTCNTCNAARACNCCNAGYGGN GTNAAYGGNCCNAARGCNCCNYTNAAYMGNYTNAGYTCNTCNAAYGCNCCNAGYGCNTCN AAYGGNYTNAGYTCNTCNAARCCNGCNGCNTCNAAYGGNGTNAGYYTNTCNAARGGNCAY GCNGTNGCNGTNTCNTCNACNGTN------------------AGYGTNACNTTYACNTCN GCNGTNTCNTCNCCNAGYAARGTNACNGCNAAYTTYGGNAGYCCNMGNAGYGGN------ AARTCNTCNTCNGARTCNCCNTCNTCNMGNGCNAARGGNCARACNGARCARACNAARGCN GCNAARAGYAARAARAAYAARAARAARAAYAARAAYGGNGAYGTNCAYGAYCCNGARGGN GTNTTYATGCCNAARTCNGARTCNGARYTNAAYGGNGCNGTNGAYGAYTTYGARMGNGAR YTNGARGARTTYAARMGNTTYTGYTAYGARACNTCNGARCCNAARGARAARMGNAARYTN GCNGTNAAYGTNAAYYTNAARGAYATHTTYAARAARAARTCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CCNGGNTCN AGYCAYGGNAGYYTNAAYTCNAAYMGNCCNACNTGGYTNTCNGARAARGAYYTNGARCAY TCNAARGAYATHAAYATHYTNGGNYTNACNGARCAYGGNAGYTAYAAYMGNGAYAARTAY GGNAARAARCCNCARGTNCAYAAYTAYAGYYTNATHGGNGAYATHYTNGCNCCNAARATG GAYTTYAAYACNGTNMGNCCNAGYGARGARGARAARACNGGNYTNGAYGGNACNAARACN AAY---GTNGCNTGGGGNCCNGGNMGNCARYTNCCNCAYAARYTNATGGAR---GARCAR ATHTCNAARAARMGNACNAAYTCNAARAGYGTNATHGAYYTNCCNCCNAAYATHMGNCAY CARTTYGGNAGYMGNGTNTGYGAYACNYTNYTNTCNGAYCARGCNATHGTNACNYTNGCN YTNGARMGNCARAARTCNAARATGGGNCCNCARMGNCCNTCNAARAARCARAAYGTNAAR GGNYTNCCNGTNAAYYTNAAYAAYACNTAYGARAGYYTNGGNCAYACNACNMGNTAYAAY GTNTGYCCNGGNGTNAGYTCNGGNCAYACNATHAGYMGNACNAARGAYGARTTYAAYGAY ATGGTNCAYYTNMGNMGNGAYCCNAAYACNGAYGARTTYMGNTAYCARMGNGAYGARYTN AGYATH---TGGGTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TAYGARYTNTTYGAR AARGAYATHAARGTNYTNCARACNTCNTTYCCNAGYCARACNMGNMGNTTYTGGAAYACN ATGTCNGCNTCNGCNMGNCAYGTNTTYGARCARCARGAYCCNTGYTAYCCNAGYGTNATH YTNATGGCNTCNCAYAAYAARAAYCARMGNYTNAAYGCNTGYYTNGCNAARAARATHGCN GCNACNTTYTCNAAYTCNMGNGGNATHAAYTCNMGNGGNTCNGGNACNGAYGTNGARGTN TTYAARCAYYTNGARCCNGARAARCARAARAARTAYYTNGAYGAYGCNYTNCARTCNGCN TTYCARCARGAYGGNGARAARGCNTAYGTNATHAAYAAYGTNCAYTCNYTNTCNCCNAAR GCNGCNYTNYTNYTNCAYGGNTTYTGYGAYGGNGAYAAYGCNCCNTAYCARGAYGTNATG ATHATHYTNACNTTYCARGTN---------GARGAYMGNATHGAYTTYCAYTCNGTNAAR GARGTNGARGAYTTYYTNGTNGGNATHTGGAGYCARGGNYTNGAYATGGAYAARYTNTCN GCNYTNATGAGYMGNATHGCNAAYAAYCCNGTNGTNYTNATGCARGARGARGAYAGYGTN ATGAAYCARATGTGY---------------GARAARTGGYTNTGYMGNGARYTNGGNAAR YTNGGNATHGAYTCNAAYGARGAYAGYGCNMGNTAYATHYTNTCNATGGARAGYAGYAAY GAYYTNGARGARTAYATGYTNGARYTNYTNGAYGTNTCNAAYCCNAARGTNMGNTTYTTY YTNCARGARYTNAARGAYMGNTAYAGYGCNAARGGNAAYAARAARGGNGTNCARGTNTAY MGNAARGARAARGARACNGAYCCNTGGGARGAYAARTCNAARAARAARAAYAARTCNGCN TCNAGYGGNGCNAARAARCARNNNTCNTCNAAYATHCARATHTCNAAYGGNAAYATHCCN GARYTNTCN---AARAARYTNAARCAYGARAARGCNTCNYTNGTNGAYTCNCCNTCNAAY TCNGGNGARATHGGNGTNGGNGCNAARAARAARTCNAARTAYGTNCCNYTNTAYAGYAAR GARGGNCARGARAARGCNGTNGTNCARYTNTCNGGNMGNCAYAARTGYGARTGYCARGCN GCNAARCAYAARYTNGTNAAYAAYTGYGTNCARTGYGGNMGNGTNGTNTGYGCNCARGAR GGNGCNGGNCCNTGYGTNTAYTGYGGNTCNYTNGTNTGYAGYCCNGARGARATGGARATH YTNGAYMGNGGNTCNMGNAARGCNGARMGNYTNMGNGARCARYTNATGMGN---GARAAR TCNAARGGNYTNAGYGARACNGGNCARTCNYTNYTNCCNATHGGNTTYAAYCAR---GCN MGNGARGARGARGAYAAYGARAARGCNYTNAARCAYMGNGAYAARYTNYTNGARTAYGAY MGNACNAGYGTNMGNMGNACNCARGTNATHGAYGAYGARTGYGAYTAYTAYGCNACNGAY TCNAAYCARTGGYTNMGNCARGARGAYMGNGARAARYTNMGNAARMGNGARGARGARYTN MGNGARTCNMGNCAYGGNTCNMGNMGNGAYMGNAARATHACNTTYGAYATHGCNGGNMGN ------MGNGTNYTNGAYGCNGARGARGAYGTNGGNAARACNATGTAYAGYMGNGARGAY GCNGTNATHCARGARGTNCAYTAYGGNAARTCNGCNCCNAAYGGNGTNAGYCCN---CAY YTNGTNAAYTCNTCNTAYGAYTTYGARCCNCCNACNTTYYTNGAYACNCARCCNGTNAAR TGGGGNCCNGARACNAAYAARTCNCARTCNGCNGAYCAYGTNAAYCCNCARTCNTCNTCN MGNMGNATHCARGAYAARGARYTNCARGARATGAGYGAYGARGGNATGTGYATGAGYATG CAYCARCCNTGGGCNTCNYTNYTNGTNGGNGGNATHAARATGCAYGARGGNMGNACNTGG TAYACNTCNCAYMGNGGNMGNYTNTGGATHGCNGCNACNGCNAARACNCCNGARAARGAR GARYTNGTNGARATGGARCARTTYTAYMGNCAYCAYTAYMGNGAYTCNAARYTNACNTTY CCNAARGAYTAYCCNACNGGNTGYYTNYTNGGNTGYGTNAAYGTNGAYGAYTGYYTNGAY CARGAYCARTAYMGNGCNAARTTYCCNCARGGNGARTCNAAYTCNCCNTAYGTNTTYATH TGYACNAAYCCNTCNAAYYTNATHGTNAARTTYCCNATHAARGGNAARCAYAARATHTAY AARYTNGARTCNCAYATHCAYCARGCNGCNAARAARGGNYTNMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MGNGARGARGCNGARGARGTNTGY MGNAARGCNAAYYTNGTNGAYTTYTAYTTYGAYTCNTGYGTNTTYGAYYTNATGGCNACN GGNGAYMGNAAYTTYACNYTNTCNGCNYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TTYTTYACNCARCARGARTAYTTY YTNAGYTTYGCNAAYATHAARMGNCARMGNGTNTTYCARGTNMGNAGYGARACNAARATH ATGGCNGCNMGNACNGCNTGGCARACNYTNCAYGTNATHAARTAYTAYTAYATHYTNTAY TTYYTNTTYGGNTCNYTNCCNMGNGTNTGGATHTGYACNTCNTTYMGNATHAGYGARGAY TCNGARGCNTTYCCNYTNGAYTCNATGGTNGGNYTNYTNAAYYTNTCNYTNYTNTGGAAR GCNTAYYTNACNTCNTTYGCNYTNACNTTYGCNYTNTCNTTYTCNATHGTNYTNGCNAAR GTNYTNCAYACNGARCAYYTNGARTTYCCNGTNACNAGYATHATGGARAAYTCNAAYGAY MGNACNYTNCCNGAYGCNYTNGCNTGYAAYTAYTCNCCNYTNYTNCARCAYYTNGCNTTY TAYGAYYTNGAYTGYYTNGGNAARGTNGTNTCNCCNMGNATGCARGARYTNYTNAGYYTN AGYCARCCNGGNGGNCAYCCNAARGTNTGGGTNTCNGTNAGYGGNTCNGCNYTNTCNGCN ATHMGNGARYTNACNAAYCARGTNAARGARGARAAYTGGTCNGTNATGTCNAARGTNCCN ATHAAYCCNCAYAAYGGNGTNGCNAAYGGNAAYGGNTTYTAYACNTCNGARCAYYTNGGN GAYMGNATGGAYTCNTCNYTNATHTAYMGNGGNGARATGACNAARGAYGGNGTNCARACN GARGTNGARAARCCNAGYATHATHTCNCARTGGATHGGNMGNATGTCNTCNGTNCCNATH YTNTCNCARYTNYTNGTNCAYAGYCAYGAYATHAAYAGYAARMGNYTNTTYGCNTCNTGY CARAARCARATHTGGGCNGTNGARAGYYTNTCNCAYATHGCNGTNMGNGCNTAYACNGAR GAYMGNTTYGGNGTNGTNCARGGNTCNYTNCCNGTNATHTTYATGACNYTNYTNGARYTN CAYGARACNYTNGARAARCAYTTYAARYTNAGYACNTCNTCNMGNMGNACNAAYGGNACN GCNTAYTCNTCNAGYGAYTGYGTNATHMGNTAYAARYTNCAYTCNGTNYTNAARGCNTCN YTNTAYMGNATGGTNAAYACNTAYAARGCNCAYYTNGCNGAYATHAARYTNAAYACNGAY GARATHAARAARYTNATGCCNTTYATHCARTAYACNYTNTTYAARGCNATHCCNTAYAGY TTYTAYGARCCNGGNACNACNTAYTTYTGGGTNCAYTTYGGNYTNGTNATHYTNGGNTTY GTNATHGCNGTNGCNACNYTNATHGCNCARTGGMGNAARCCNGCNCCNTAYGGNAARCAY GAYGTNGCNGGNGARAAYTGGGGNCCNTCNATHCCNCARMGNYTNTCNCAYATHATGTCN GAYGCNGTNTCNGGNGTNGCNATGTTYTCNGTNGTNYTNACNATHTTY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GGNTTYATHYTNCAYCCNACNGGNACNCAYTAYATGCCNATHTCN GTNCAYAAYTCNAAYATHTCNAAYYTNTTYGARTCNGCNGGNGAYCARGARGGNATGCCN GTNTTYCAYCCNATHAGYATHCCNGTNCAYTTYMGNMGNCCNGTNATH------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARGARGTNYTNGCNGGNAGYCCNCCNGGNCARGAYGARTTYGTNAGYGAY GCNTTYCARGGNAGYAAYATGACNGARGARGAYATHMGNAARGARATGGARCARCARYTN MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNCAYGTNAARGTNAAYCCNGAYGCNCCNGTNTGYAARGCN TTYYTNCARGGNTTYTGYCCNYTNGGNCARAARTGYAARAAYYTNCAYTCNTTYGTNTGY CCNTCNTAYGCNATGTCNGGNMGNTGYCCNMGNCARGAYGCNTGYCARATGYTNCAYMGN YTNACNAARAAYATGCCNATHYTNAARATHGARACNAAYYTNCCNMGNGAYAARATHCCN GARAARTTYYTNCARAAYGCNACNGAYGTNATHTCNTCNGARYTNGGNAARCCNGGNTCN TAYGTNTGYATHCARATHTGYCCNGAYCARGTNATGAGYTTYGGNGGNACNAGYGARCCN TGYGCNAAYATHACNYTNAAYTGYATHGGNGTNGTNGGNCCNGARAARAAYAARGARYTN GCNCCNGTNYTNTCNAARTTYATHGARMGNCARYTNGGNATHAARCARAAYMGNTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AARGARTGGGAYGGNMGNYTNAARATGGARYTNTCN MGNGCNATHAARTGYCCNTCNGTNCARTAYCARYTNGCNGGNGCNAARAARATHCARCAR GARYTNGCNMGNCCNGGNGCNYTNGARMGNTTYATHGAYGAYCCNCARGTNGTNAARGAY ATHMGNATHACNTTYGCNGAYCARTAYAGYYTNGAYYTNGGNCCNGARGGNGAYAARGCN GTNTCNYTNGCNYTNGARTCNCCNGAYAARTTYGTNYTNAARCCNCARMGNGARGGNGGN GGNCAYAAYYTNTAYGGNCARGAYATHGTNGAYTTYTTYAARGARCAYGCNAGYAGYAAR GARMGNAAYGCNTAYATHYTNATGGARMGNATHTTYCCNYTNCARCARCARAAYTAYYTN TAYAARGARGGNGTNGCNTTYCARYTNTCNACNGTNGTNAGYGARYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGGCNGARAARTTYCARAARGTNYTNGARCARACNGCNYTNTTYGGN CCNATHGCNGTNGGNGTNATGATGGCNAARGARAARGGNATHTTYTCNTCNATHATHAAR TCNGAYAARCCNYTNACNTCNGARGARATHGCNAARGARAAYAARYTNAARGARMGNTAY ACNMGNGARYTNYTNGGNTGYYTNTCNAGYGCNGARTTYATHAARGTNTCNTCNAAYGAR GAYGGNGTNAAYGTNTAYTAYYTNGAYGCNCCNGCNAARCAYATHYTNTCNGARACNAAY TTYYTNCCNGARATGAAYTTYYTNAARATGYTNATHGTNMGNTAYTCNGARATHAGYGAY YTNATGGAYGAYGGNAAYGCNACNGTNGTNMGNTAYGGNGAYAARTTYTTYAGYYTNYTN GAYGAYATHAARATHMGNACNACNGGNGARYTNATHGARTCNATHYTNGCNAAYGTNCAR GGNYTNMGNGARAARYTNGARGCNGGNATHGAYGTNATHGARATHGGNAGYGGNAARGCN GTNTGYYTNGTNMGNYTNGCNGGNATGTTYCCNAAYAGYACNTTYACNGCNACNGAYATH CARTCNGAYTTYGCNGARACNATHGGNAARAARTAYAGYCAYYTNACNAAYATGAARTTY GARACNYTNGAYYTNTGYGCNYTNCCNGARACNATGGAYAARAARTAYGAYTGGGCNYTN AGYATHGAYGTNATHCAYGAYYTNCCNCAYCCNMGNGARGGNYTNAARGCNATHMGNAGY YTNATHAARTCN---GAYGGNGTNTAYACNTTYGARGAYATGTCNGGNACNGGNAGYCAY ATHCARGAYGTNGGNGAYAAYGTNGCNGCNGCNTTYTAYACNYTNGGNACNTTYYTNTGY ATHCCNGARAGYTTYCARTCNGAYGAYAGYGARGCNCAYGGNCCNTGYTGGGCNAARCAR ACNTGYYTNGAYTAYGCNAAYTCNGTNGGNTTYGAYACNACNGCNATHCCNYTNGARGGN AARAARATGYTNTTYATHGCNAAR------------------------------------ ---------------------------------------------------------GAR CCNCCNCCNTCNTAYGAYTCNYTNTTYGGNMGNGTNAARGCNGCNAARGCNGARTCNTCN GGNGCNGTNGAYTTYTTYAARACNTTYATHATHATHATHYTNTCNACNATHGGNTTYACN ATHYTNYTNGGNATHTTYATGGCNGTNCCNGTNTCNATGATHGTNATGGGNGCNYTNTAY YTNGAYGAYTGYGAYGCNGARMGNATGATHCCNATHTAYYTNATHGTNGCNGGNTGYTTY GGNTGYGCNAARAAYYTNTTYAGYYTNGTNCARMGNTGYMGNAARACNGARGARGARMGN CARGARGAYCARAARAARGTNAAYCCNYTNGARAGYGTNGTNAAYTGYTTYATHTTYGCN TGGTTYATHGCNGGNTGYGTNTAYATHTAYMGNACNAARGAYGAY------TTYCARTCN CAYGAYCCNGAYTCNGAYTAYTGYAAYTAYAAYYTNTAYTGGTTYGCNTTYTGGATHACN ACNGCNGCNTAYATHATHATGGCNYTNGGNTGYYTNTGYGTNTGYGGNGCNGGNTGYYTN GCNTCNTGYTTYGTNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR AAYTAYACNGCNGTNATGTAYTGYYTNACNTGYYTNGARGCNTGYGTNAARAAYTGYTGY MGNMGNTTYCAYYTNCARGTNGCNAAYAARGAYTTYYTNCAYGAYYTNATHAARATHATH GGNCCNAARAAYGAYCCNCCNCARGTNATHCARGARAARGTNYTNAGYATGATHCARACN TGGGCNGAYGCNTTYMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNGTNGGNMGNGAYTTYYTNAGYYTNAARCAYTTYMGNGCNGAYGAR ATHAARCARTTYYTNTGGACNGCNAARGAYYTNAARACNMGNATHAARGAYAAYGGNGAR GTNTTYCARCCNYTNGCNGGNAARACNGCNGCNYTNATHTTYCARAARMGNAGYACNMGN ACNMGNYTNTCNTCNGARYTNGGNYTNGCNMGNYTNGGNGGNCAYGCNGCNTTYYTNGGN CCNGAYGAYATHCAYYTNGGNGTNAAYGARAGYACNGARGAYTCNGCNMGNGTNYTNACN GGNATGGCNGAYATHATHYTNGCNMGNGTNTTYGARCARGARTTYYTNGAYACNYTNGCN GAYAARGCNTCNGTNCCNGTNATHAGYGGNYTNTCNGAYYTNYTNCAYCCNYTNCARATH YTNGCNGAYTTYATGACNYTNCARGARCAYTTYGGNTAYYTNMGNGGNTGYAARATHGCN TGGGTNGGNGAYGGNAAYAAYATHYTNCAYTCNYTNATGTAYGGNTGYGCNAARYTNGGN ATHGAYYTNAGYGTNGCNACNCCNGCNGGNTAYGARCCNGAYTCNGAYATHACNYTNGAR GCNATHAARATHGCNGGNAARACNGGNGCNTCNTTYCARATGGGNAAYAGYCCNGARGAR GCNGTNTAYMGNGCNGAYGCNATHATHACNGAYACNTGGGTNAGYATGGGNCARGARGAR GARAAR---AARAARMGNYTNGCNGAYTTYGCNGGNTAYCARGTNACNMGNAARATGYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGTCNGARGGNTCN---TCNCCNAARMGNCCNMGNYTNGAY ---GAYGAYAGYGGNAARGAYGAYCAYCAYGAYAARTAYAGYAARATHMGNGAYCARGAY GAYCARGGNAGYTAYAGYAAYCCNMGNAARMGNMGNGGNGAYACN------GAYGARGAY GAY--------------------------------------------------------- ------------------------------------------------------------ ------------ATGAARGAR--------------------------------------- ------TGYGAYGARATGAARTCNGAYCCNGCNATHAAYYTNGTNTTYCARMGNATGTCN AARGARATGGARGARCAYAARGARAARYTNAARCARAARCARAAYGARYTNAAY------ ------------------------------------------------GCNTGGAARTTY ACNCCNGAYAGYCARACNGGNATGMGNYTNATGGCNAARTGYMGNATGYTNYTNCARGAR AAYGGNGARYTNGGNAARATGATHTCNTCNGGNMGNACNGCNMGNYTNGARGGNGARATH TCNYTNCAYAARGCNYTNGTNGCNGARATGAARAARAAYCARAARGARYTNGAYGARTTY GTNGGNGARYTNGARGARGAYGTNGARGGNATGCARGGNATGATHTTYATGYTNCARCAR CARYTNAARGARGCNMGNGARCARATHTCNMGNYTNCARCARGARAAYGARCARYTNMGN ACNYTNCARYTNCCNACNGARCCNGARCCNGGNGGNGTNGAYAARAAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TAYGAYGARAGYGARCAYATHYTN ACNAARTAYACNYTNGGNTCNGTNGTNTGGGCNAARATGGAYGGNTTYCCNTGGTGGCCN GCNATGGTNGAYACNGAYCCNGAYTAYGAYACNTAYTTYGARYTNCCNACNGARTCNAGY ATGATHCCNTAYYTNTAYCAYGTNACNTTYTTYGAYGARCAYGTNTCNMGNGCNTGGACN AARTCNCAYYTNATHGCNCCNTAYGAYCAYAARTCNYTNCCNACNGAYAARGTNACNGTN AARTCNCAYTCNTAYAARAARGAYMGNCARATHGCNATHACNAAYGCNGARATHGCNYTN AAYYTNAGYYTNCARAARMGNYTNGAYMGNTAYACNTTYTCNAARMGNTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNACNMGNATGATHACNYTN GAYAAYGTNGAYAARATHTTYTCNGARTAYYTNTCNTGYGTNMGNACNATGAGYYTNAAY GAYGTNMGNTTYYTNATGCARAAYGTNTCNGARATHYTNAAYGARAARCCNGAYGTNGAY AARGCNTGYGTNGAYTTYYTNAARAAYYTNYTNGCNACNGARAARCCNGARATHGTNAAY GARGTNGTNCARATHYTNCCNTCNATHAARYTNAAYGAYGAYAAYCARTGGMGNGAYATH YTNACNTCNGTNGARGARAARTAYGAYYTNATHACNTCNGTNGARGCNAARGTNGCN--- GCNTCNGCNACNTCNTGGGARGTNGTNGGNAARAGYAARAARTCNAARGGNGAYTCNAAR ACNYTNTCNCCNGCNMGNGARAARGARYTNYTNGAYAAYATGCCNMGNATHTCNAAYCAR GAYCCNGTNCARYTNGAYGARACNGTNTAYTCNATHTTYYTNCCNAARGARCARCARAAR CARGCNAAYGCNGCNAGYGCNAARGARGAYGCNAARCARAAYGCNAAYAARAARGCNAAY CARAARAARAARAARCARGAYGARCAR------AARAARAARCARAARCCNGTNGAYYTN GARACNGCNYTNTCNACNYTNGAYTTYMGNGAYYTNGAYAGYATHYTNAGYAARTCNCAR GCNTAYTTYCCNAAYCAYCCNGTNGTNTGGYTNAARGAYGTNGCNTCNTAYYTNAAYATH AARYTNGARAAYACNATHGARACNGAYCCNGTNTAYAARGGNAARTCNACNAGYTTYCCN YTNGAYGCNGTNCCNACNGCNTAYGCNAAYGTNYTNCAYTCNTTYATGAARAARTTYTCN AARCARACNYTNGAYAGYATHCAYTAYTAYGGNATHCARACNATGYTNCARGARGCNTCN AARGGNATHCCNGTNCAYGGNTAYAARATHTTYYTNCARYTNYTNGCNCAYACNAARCCN GAYATHGTNATGGAYCARATGCCNCARTAYYTNGARYTNYTNAARATGAAYCARAAYAAY CCNTCNAARTGYYTNTCNGTNYTNTGGGCNYTNGGNCARTGYGGNTTYAARAAYTTYAAY TGYGGNYTNAARGTNTGGYTNAAYYTNATGYTNCCNGCNYTNGARGTNMGNCARGTNGCN CAYTAYCCNGTNGAYTAYYTNGARGCNYTNGTNAARTCNAAYAARAARGTNAAR---AAR ------------AGYTTYGGNYTNGTNACNYTNMGNGAYTAYTTYCARGTNATGGAYGTN TTYTTYAGYCCNCARTTYACNYTNGCNAAYGAYYTNAARAARMGNYTNACNGTNYTNTAY CCNTTYATHAARACNYTNGCNTAYGGNGARGARCCNTCNMGNCAYYTNMGNACNTTYTTY CCNTCNTAYYTNACNMGNTAYGGNTCNACNAAYTCNCARCCNATGAARGAYCARYTNYTN GARTGYYTNACNCAYTGYYTNATHACNGAYAARCARTCNTTYAGYGTNTGGTGYCARATH TAYACNAARCAYYTNCCNGCNTCNAGYCAYYTNYTNGAYCAYATHAAYMGNAARTGGTCN AARYTNTCNTCNAARTTYGAYAARAARATHTGGACNGARACNYTNAARTCNTTYTCNGTN ACNAAYGARGARYTNGARGTNCARAGYAARGGNAARGCNCCNGGNYTNAARATGTGYCAR ACNGCNTCNAARGAYYTNYTNACNAARYTNACNMGNTTYAGYTTYCCNTGGAGYYTNYTN GTNTTYTTYYTNGTNTCNGTNTTYGCNGCNATHGTNATHTAYGAYGTNTCNTCNAGYCCN AGYTTYMGNTCNTCNAARTCNATGCARTTYYTNGARCAYTAYGGNATHYTNGCNYTNYTN GARMGNACNTAYCARTGYGTNAGYAAYGCNTTYAAYYTNTCNATGAAYTGGYTNAARGTN AAYTTYCCNGTNTAYTAYGCNACNATHMGNGAYACNGTNGGNCCNTTYATGATHYTNGTN TGGGARACNTCNAARGAYTTYGTNATHAAYGCNGARGTNGCNTCNMGNCCNTAYMGNGCN YTNATGGTNGARAARGCNGTNCARTTYTAYTAYTGGGTNTAYGARYTNTCNCCNGARTTY TGGAARMGNTGYGGNGARYTNTCNTGGYTNGCNYTNGARATHYTNAARGAYTAYGCNYTN MGNATHTGGGCNYTNACNGTNTAYTTYGCNGGNCARGCNGARCAYTGGYTNACNGARCAY GTNYTNACNGGNTCNTTYTCNAARGARACNYTNAARGTNACNGCNYTNMGNGGNGTNGAR CAYYTNCARAAYTGYACNTCNTTYYTNGTNTCNTGG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGGCNGAYTAYACNGARACNAARACNTCNATH TCNCARCAY---YTNAAYGARGCNAARGARTTYAGYAAYATHATHTCNAGYGTNACNGAY CARAGYTAYCARGAYGGNGTNATHGAYAARATGAAYCAYATHGARGTNGARATHGARMGN AARATGAARATGCARGARAAYGTNACNTCNAGYAAYCARAARACNGTNCARGARYTNGAR GCNGARGCNGARGCNYTNTCNTTYAARATHAAYTCNCAYAARAARAGYATHAAYYTNYTN CARGARGARATGAAYCAYYTNTCNAARGARAARACNYTNYTNAAYAAYGTNCCNGAYGGN GAYATHATGGCNACN---AARGTNAARCARYTNGARGAYGARGAYYTNGTNTTYMGNAAR CAYYTNGGNATGGARGTNMGNAARGTNAARGGNGGNTGYYTNCARGTNGCNYTNAGYCAR ATHGAYCAYAARCARCCNAAYTCNYTNTTYYTNTTYTCNYTNMGNYTNGAYGARAAYMGN MGNTAYAAYATHTCNGAYTGYAARCCNTAYATHGCNGAYYTNGAYGCNATHGTNGARAAR YTNAAYAGYGAYAAYGAYTTYCAYAARTTYGTNCAYACNATGMGNMGNMGNTTY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNAARMGNMGNTAYAGYGAYGTNYTNGAR---GAYCCNTAYMGNGGNCCNCARGAR TTYATGGARGCNGGNGCNMGNGGNTTYYTNGTNACNTCNATHCCNGAYMGNGARGARCAY GCNATHGAYGARGCNGTNAARGTNYTNMGNAARTCNTGYGTNAARYTNTTYGGNGGNATH MGNCCNYTNAARMGNGARGAYGCNTCNTTYGCNAARGGNTAYGTNATGGTNGAYTTYATG GAYCCNGARAGYGTNGTNGCNYTNCCNCAYCCNGAYGCNGAYAARGARGARAARGARAAR CARTCNGARGCNGARGCNGAYGCNACNAARGARGARGTNAARGARAGYGARGAYATGGAR GARGARACNAARCARGARGARGCNAARGARGARACNGARCCNGARACNAARGARGARGCN GARCCNGARACNAARGARGARGCNGARAARGARGARGCNGARCARGARACNAARCARGAR GCNGARGARGARGCNGARAARGARAARGCNGAYACNGAYAARGTNGAYGCNGARGTNAAR AARGAYGARGGNACNGAYACNAARACNAARGARGARAARGARAARGARGARAARAAR--- ------------------------AARAARGARGARYTNMGNAARAARMGNAARGARGAR GARGARMGNGCNAARCCNCCNYTNATGYTNGCNCCNCAYAARTTYAARAGYTTYMGNACN GARYTNMGNAAYATHATGTTYATHAARTCNGAYATHGTNGAYCCNGTNGTNGTNGCNACN ACNGCNTTYGAYYTNATHATGGARMGNAARCCNYTNYTNACNGAYTGYATHAAYCARATH YTNCCNGTNCARGGNGTNTGYGAYAAYGAYTAYAARCARYTNGARATHATGTGYMGNMGN GTNYTNGTNCCNTAYGTNGGNGARCAYYTNGARGARGCNCCNAGYTTYGGNGTNATGYTN GTNGAYAARATGTCNGARCCNGGNGCNGARGTNYTNYTNGARGTNGTNMGNAGYGCNATH TGGTGYYTNAAYCCNTGYGCNTGGCARTGYTCNCCNTGGTGYGARCCNGAYGTNGTNATH CAYGTNGARATHATHGGNAGYAARATHATHYTNAGYGCNATGTCNCARTAYATGAARTAY MGNCARTAYAGYCCNTTYGCNYTNCAYGARYTNGGNCAYGGNAARGCNGARGAYGARGAY ------------------------------------AAYYTNYTNMGNGARMGNMGNGAR AARAAYGAYGAYGAR---------AARGAYMGNGAYAARGAYAGYAARMGNMGNMGNAAR TCNMGNGGNAARGGNGAYTCNTCNGGNAARAARGARGARAARGARAARAARGARGARAAR GARAARAARGAYGAYAARGARAARAARGARGGNAARGARAAYAARGARGTNGARGARGAR ACNGAYTCNYTNGARGARAARGARAARCCNACNGARGTNGTNGAYGARAARGARACNGAR CCNACNGARGCNTCNGAYGARAARAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNTCNATH GAYAGYCARTGYGCNMGNGAYAAYCCNGARGTNTAYACNATGGARACNAGYGAYAAYGCN MGNATHAARTCNMGNGTNAGYATHGCNATHGGNYTNATGAARGCNYTNTCNTCNGTNGCN YTNTCNMGNTAYGGNGAYGGNGARATHCARMGNATHTGGYTNMGNGGNACNAARTCNGAY AARYTNGCNTGYACNATHAGYYTNYTNCAYATGCCNATHGGNTGYGGNMGNYTNCAYMGN TAYYTNCCNGTNTCNAARAAYGAYAAYYTNCAYCARGCNATHCCNYTNYTNTTYATGGAR GARGCNGCNCCNGTNMGNGARAGYATHGTNACNGCNTTYAGYYTNYTNGCNCAYYTNACN GGNATHACNAARYTNACNCCNGCNATHTCNMGNYTNAARCCNTGYCCNGAYTCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AARGGNATHTCNCAYGGNCAY AGYGTNMGNYTNMGNCARYTNAGYCAYGTNYTNTAYGAYMGNATHGTNGARATHATHAAY TCNGGNGARYTNTCNCARGGNATHYTNGARAARCARGTNTCNATHACNTCNGTNAAYATG GCNAARGAYATGAAYAAYYTNAAYATHTAYTGGGAYTCNGAYMGNGAYGAYTGGGARCAR GTNGARCARYTNYTNCARGCNYTNGGNGGNAARYTNMGNAGYYTNYTNATHTCNTAYCAY GTNYTNGGNMGNATHCCNCAYATHGTNTTYGTNAARGAYAAR---ACNATHGTNAAYYTN AGYCARYTNACNGARYTNTTYGARAARGCNGAYTAYGGNCCNGAYTAYGTNCCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AGYCARAARTGGATHCCNCCNYTNCCNCCNAAYTGGGARGGNMGNTAY GAYTAYGARMGNMGNCAYTAYTTYTTYATHAAYCAYGTNACNAARAARACNCARTGGGAR GAYCCNMGNTTYCCNAARMGNCARGAYCCNCCNGTNGCNGCNCCNMGN------------ ------------CAR------------CARGARGARGARTCNACNYTNTCNGARGARGTN GAYMGNGAYGTNGTNGCNAARYTNTGYMGNGARTTYCCNAARGCNACNAARGARYTNGTN GTNGAYYTNYTNGTNACNTGYCAYCAYAAYGARMGNGARACNMGNGARCARYTNCARGAY TTYGGNTTYTCNACNGCNGCNMGNGARTCNMGNTCNMGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTNCCNAARGARGGNGARGAR GTNYTNGAYGARGARYTNTAYGARGAYAARGAYYTNGARGGNGTNGARGARCAYAARTCN ATHATHYTNCAYYTNYTNTCNCARYTNAARYTNGGNATGGAYYTNACNAARGTNGTNYTN CCNACNTTYATHYTNGARMGNMGNTCNYTNYTNGARATGTTYGCNGAYTGYATGGCNCAY CCNGAYGCNTTYYTNAARATHCCNGAYATHCARGAYGCNGARGGNMGNATGYTNGCNGTN YTNGARTGGTAYYTNACNTCNTTYCAYAAYGGNMGNAARGGNACNATHGCNAARAARCCN TAYAAYCCNATHATHGGNGAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATHAARAARGTN YTNCCNAARAAYGAYAARGARTGGGARTGGTGGATHAARTTYMGNAAYCCNGARGAYATH CARAARCAYCAYGARTCNTAYYTNTAYTGYGARATHGCNTTYTAYGTNYTNGGNTTYYTN ACNTTYTGYCAYGCNATGGCNAGYGGNGGNMGNTAYAARTGGYTNTGGYTNGCNACNATH GCNCAYGGNYTNACNGTNGARTCNYTNAGYTAYGTNATHCCNGAYATHGAYAAYTTYTGG CAYAGYCARTCNATGGTNATGTTYATHGGNCARMGNYTNCCNYTNCAYATHATHYTNYTN TAYCCNATHTTYYTNTAYACNTCNGTNGTNGCNGTNTCNCAYATGAAYYTNMGNTGGTGG GCNGARCCNTTYGCNGTNGGNATHTCNGCNGTNYTNYTNGAYYTNCCNTTYGAYGTNATG GGNATHAARYTNATHTTYTGGACNTGGCAYGAYGAYGAYCCNAAYATHTAYGAYMGNCAY TAYTGGGTNCCNTGGACNTCNTTYTAYTTYCAYGCNGCNTTYGCNTCNTCNTTYGCNTTY ATHTTYTTYGGNATHAARAARATHTTYTGYTCNMGNGGNYTNAARTTYCARAGYAGYGGN TTYTTYYTNGARYTNCCNATHGTNATHGTNACNGGNYTNTGYGCNATGCCNYTNGGNGTN YTNCARTTYYTNCCNYTNTAYCAYACNYTNCAYGAYACNYTNAARYTNCAYTCNGARATH TGYGTNYTNTTYTTYYTNGGNTTYTAYTTYYTNGTNGTNTGGAAYTCNGAYMGNMGNCCN TTYGARTTYGCNMGNYTNAARGGNGGNAGYATGTTYAGYYTNATGATGYTNACNGTNYTN YTNCAYTAYGCNTTYTAYGTNTTYYTNGTNTTYACNGCNGAYCCNTCNACNATHMGNTCN ATHGGNATGCAYCARCCNGTNGGNCCNTGYAAYAARCCNGTNAARGTNCAYACNCCNYTN GGNCAYGTNYTNAGYAARAAYAARTAYYTNTGYYTNAARAAYTAYTCNGARGAYTAYTTY ACNYTNGAYTGYGTNAARAARCCNCCNGCNGAYAARACNGARTGGTAYACNATHTGYGGN ACNGCNTAYCCNAAYCAYAARGARTAYATGATHATHGTNTGYGCNTAYTGYYTNYTNGGN YTNTTYTGGTTYTAYCARGCNTTYTGYGGNTCNGGNCARCARCCNMGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR GAYGARGAY---------YTNCCNCCNGGNGTNMGNAARCAYAAYMGNTGYCAYAGYAGY AGYAGYTCNGAYTCNGARGAYGARAARAARAARCAYTCNAAYTCNGAYTCNTCNGAYTCN GARTCNGAYAAYTCNGCNAARAARGAYGGNAARGAYGGNGAYGTNTCNCARYTNCCNGTN YTNGARAARTCNAARTCNCARAGYAARGARAARGARATHCCNTCNAARAARCAYAGYMGN TCNMGNTCNGAYTCNMGNTCNMGNTCNMGNTCNGCNTCNCCNAARMGNMGNTCNTCNGAR AARAGYMGNCAYTCNMGNTCNMGNTCNMGNGAYMGNMGNCAYAARAARGARMGNMGNMGN MGNTCNTAYMGNTCNMGNTCNMGNGARMGNMGNMGNTCNAARGAYAAR------CAYMGN CAYAARMGNGAYCAYAARMGNAGYMGNAGYMGNAGYMGNGAYMGNMGNGAYMGNMGNCAY GAYMGNMGNAGY---AGYMGNGAYMGNMGNMGNMGNAGYMGNAGYMGNAGYMGNAAYMGN ---------MGNAGYMGNAGYMGNGAYMGNMGNMGNGAYAGYMGNAGYCCNAGYCCNCAY GGNGGNAAR------GTNATHAARTTYGGNGAYAARGTNATHAARCCNGGNGCNAGYTTY GGNMGNCCN------ACNTCNAAYTTYTCNAARCCNGTNACNTTYAARGARAARATGMGN CARCARYTNATHAARGCNATHGARGARGGNGCNGAYACNAAYGARGTNYTNGCNAAY--- AARGGNTCNACNATHTGYACNCARTCNGCNGGN---GTNCARCAR---GTNATGCCNAAR CCNAARGGNCCNCCNATHCCNYTNATGGAYGCNATHYTNCCNTCNACNGCNAAYYTNGCN GCNATGACNGTNACNGCNTCNGARGCNGCNATGCARTCNATGYTNGCNYTNCARAARGAR GCNACNGARAARACNGGNGTNGARATHCCNAARTAYTAYAAYCCNGCNGCNATHAAYCCN ATGAARTAYGCNGARCARGTNCARAARMGNAARYTNYTNTGGTCNAARGCNAARGAYAAR GAYGTNAAYTCNCARTGGCAYGCNACNAGYYTNTCNGGNGAYGCNGAYGAYAARTCNAAR GARAARTTYMGNAARYTNATGGGNATHAARGAYGAYGCNTCNAARGGNGARGGN------ ------------------GARCARGARGARAARCARAARCARATHTTYGAYCARYTNAAY AARGARTAYGARTAYGCNMGNATGGCNACNCAYACNCAYMGNGGNATHGGNYTNGGNTTY GGNTCNGCNGGNTAYCARCCNCCNCCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------GGNTAYACNYTNYTNCCNCARGARCCN---------GARGAYGAYGAYGAYAAY AAYTAYAAYGAYGTNGCNAAYTAYYTNGCNAGYTAYAAYGCNATGAAYGAYAAYTCNGCN ACNGCNTCN---------------GAYMGNCARCAYGAYTCNGTNCCNGAYGARGTNATH MGNTCNGARGCNGCNGCNTCNGCNCCNACNGTNGAYGCNTCNAARACNAGYYTNCAYCCN GARYTNATHGCNAARTAYCCNGAYGGNAARGTNCCNTCNTAYATGCARGTNCCNGAYATH CCNGCNAAYAGYAARGAYGTNYTNTGGAAYAARAARMGNTCNGARAARAGYATHCCNTCN YTNGAYTCNGCNCARGARAAYAARATHGTNAARGCNATGTCNGGNTTYTCNYTNCCNACN GARAAYATHCCNGARTGGGCNMGNACNATGTCNCCNGAYGAYTGGGAYMGNGTNATHTCN CAYCARATHAARTCNGAYACNTGYGARAGYCARCARAARACNGAYACNTCNYTNGARCAR AARACNCARTCNGAYTGGGTNGCNGARTTYCCNGAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TAYMGNAARAGYGCNGTNACNATHTCN GGNCAYTAYCARGTNGARGAYGAR---TCN------TAYGCNMGNCCNCCNTTYGCNGTN YTNATHGAYTAYAARAGYGTNTCNGAYGAYATHAAYAAR---GTNGTNYTNYTNGGNATH CAYACNCARCCNTCNMGNGCNTTYAARGARYTNGARCARTTYGGNCARAGYATHAARCAR GTNTAYGCNATHTTYTCNGARACNAGYGGNGTNGTNGCNATGGGNGAYTAYAAYGCNGAY TGYTCNTAYYTNAGYAAYMGNAARGARGARAARYTNGCNATHTTYAARGGNGAR---GAR TTYGAYAGYYTNATHCCNGAYGCNTGGGAYACNACNATHTCNAARGGNAGYAAYTGYGCN TAYGAYMGNGTNGTNATGTAYCCNAARAAYGTNCAYGTNMGNAAYATHAARGTNTAYAGY GTNGARAARAAYYTNGAYATHGAYAAYAARCARGCNMGNMGNGTNAGYGAYCAYTAYCCN ATHGARTTYAAYYTN------TTYAGYYTNAAYYTNTGYGTNGGNCCNACNTAYGAYCAR GAYTGYGCNYTNCAYTTYAAYCCNMGNTTYGAYCARAAYAGYGTNGTNMGNAAYCAYATG CARGGNGGNAAYTGGGGNCARGARGARACNAGYGGNGGNAAYCCNTTYMGNNNNNNNCAY NNNTTYGARATHCAYATGAARGCNNNNCAYCANGGNTAYGARNNNNNNGTNAAYGGNMGN NNNTTYTGYAAYTTYAAYCAYMGNYTNCCNMGNGARNNNNNNCARTAYATHTAYATHGAR GGNGAYGTNNNNATHCAYNNNATHCARTTYMGNGGNNNNCAYNNNNNNCCNNNNCCNGGN TAYCCNGCNCCNCCNTCNTAYCANCCNTCNNNNCCNNNNTAYCCNCCNGCNGGNNNNTAY CCNNNNNNNCCNNNNNNNCCNNNNNNNNNNNNNTAYCCNCCNNNNNNNNNNNNNNNNNNN GGN---GTNNNNCCNACNTAYAAYCCNNNNGTNCCNYTNACNNNNNNNATHCCNGGNGGN YTNNNNCCNGGNAARATHATHTAYATHTCNGGNATHCCNCAYNNNAAYCCNAGYMGNTTY NNNGTNAAYYTNCARTGYGGNCCNTAYGANTCNGGNGAYNNNGCNYTNCAYTTYGAYGCN MGNTTYAAYTAYGGNAAYGAYGTNAAYCARGTNGTNMGNACNCAYAARCARGGNGGNAAY TAYGGNCCNGARGARAARCARATHACNTAYTTYCCNTTYTAYCCNAAYGCNAAYTTYGAR ATGATGATHYTNATHGARCCNCARGCNATHAARATHGCNGTNAAYAAYCARCAYTTYGTN GARTTYMGNCAYMGNATHCAYCCNATHCAYMGNGCNGAYCAYYTNAGYGTNGARGGNGAY GTNMGNYTNACNCARGTNMGNTTYCARACNAGYACNTTYGTNCCNAAYTTYYTNGTNAGY TCNGGNACNGGNYTNACNCCNACNYTNACNCCNACNACNYTNGCNACNATHGARCARTCN TTYATGGAYATGCARCAYTCNGGNGCNMGNGAYCCNGTNACNCARAGYGGNTTYGTNCCN CCNGTNGTNGARCCNTCNAAYAGYAAYAGYGCNGAYCARTCNCAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AGYCARGARMGNTTYATH TCNCARGTNGARAARATHMGNAARACNGGNGARCARMGNYTNACNTCNTGGYTNCARAAR ATHGGNAARGCNAARAARGTNGTNAARGAYGARATHAARGTNAARCCNGCNGCNAAYATH AARATHAAYGARTAYYTNTGYAARYTNCARGCNTGYGTNGGNYTNATHGGNTGYATGYTN GGNCARGTNGAYMGNYTNGARGCNATGACNTCNGARGCNGAYAARTCNTCNTGGCARAAY GARTGYGAYATHATGGARACNYTNAARGCNAARCAYMGNAAYATGCARAAYGTNTTYGAR AARGCNAAYGTNGARCARGCNCARAARAARYTNATHGGNATHMGNCARAARMGNAGYMGN YTNAARMGNTCNMGNCAYCARAARTAYCARGARACNCARGARGTNGARGARGCNMGNCAR GCNAARGARAARGAYATHAGYGAYTGGCARCARAARYTNYTNYTNGARATGAARGAYAAR YTNYTNAARAARAARMGNAARATGGAYATGGAYCARACNYTNAGYGARGTNACNAARAAR ATHAAYGAYGCNAAYMGNYTNATHGAYACNATGACNTCNYTNGARAARYTNMGNYTNATH MGNCARGAYGCNGCNGARAARMGNGGNGAYGCNGAYYTNGGNGARTCNMGNCARAGYTTY GARCARAARATHGCNGAYATGACNMGNYTNGTNMGNTCNCARYTNGARGTNTAYAARGAR GARGARAARAARYTNMGNAARGTNATHAARTCNGARCARGARGARYTNAGYAARAARGAR MGNCARYTNCARGARAARAARGAYCARGARGARCARATHCARAARGAYGARGAYYTNCAR AARAARYTNTTYGGNATGGARAARGAYATHGAYGAYYTNYTNGAYGARGTNGARTCNAAR TAYGTNAAYMGN---------TCNAARAARCCNGARTCNAARCCNACNAARGCNGCNCAR YTNCARCCNACNAARAAYACNGTNGAYGAYGCNATHAAYGAYATHYTNGAYYTNGAYYTN GAYGAYGAYGTNGCNAARAARGARATH------CCNAGYAAYAAYGCNCCNTCNYTNTCN GCNATHAAYGGNMGNAARGAYGCNCCNAARAGYMGNTGYTTYCCNGTNCAYYTNGGNGGN AGYAARGAYGARGCNGGNYTNGGNACNTCNGTNAARACNMGNGCNTGYGAYMGNYTNMGN TGYACNGAYTGYGAYTTYCAYGTNTGYTAYTTYGAYGAYTTYTCNTGGAARAARGAYACN AAYTAYYTNTTYYTNMGNAAYAAYGTNCCNGAYTTYAARAARYTNAARTCNAAYYTNMGN MGNCARAARGGNTGYMGNGCNTAYTGYTGYCARTGYACNTGGMGNGAYATHCARTCNYTN CARGARATHTCNGAYCCNAARYTNAARTGGGTNTGYGGNAARCAYGAYTCNCCNGCNAGY GTNATHGARGCNYTNATHTGYTTYTTYTCNATHTGGTCNGTNGTNGGNYTNGCNGGNTTY CAYTCNTAYYTNACNGCNTCNGARATHACNACNAAYGARGAYATHAARGGNACNTTYACN TCNAARMGNAGYCAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CAYYTNCAYAARTGYMGNAARAAYTTYCCNAAY GTNATGATGTCNGTNTGYCCNTAYAAYGCNACNCAYGARATHMGNTCNCCNGARYTNAAR TAYCAYATGGCNCARTGYCCNAAYMGNACNYTNYTNGARAAYGARATGGGNTAYAAYGCN YTNAARAAYGCNGTNATHGGNMGNGARGARCCNATHMGNAARGGNAAYACNGAYYTNCCN MGNCCNGCNGTNATHGARTTYAAYGARGARGARAGYYTNGARAAYTGGGAYGAYGAYGAY GAYGAYCAYCCNTTY--------------------------------------------- ------------------------------------------------------------ ---------------YTNMGNGAYATHTCNYTNCARATHATHTAYGARYTNAARAARGGN MGNCARGTNTTYATHGARGAYGARYTNCAYTCNCARACNACNMGNAARAGYATHYTNAGY ACNGTNAARAARAARGTNCCNGGNTGYMGNGCNYTNYTNATGAARATHATHCCNGCNCAY GGNYTNATHCARGTNYTNTGGTCNCAYCARAAYGTNCAYGGNMGNGGNYTNYTNCARAAR TGYCAYTGYCARAAYGGNTAYACNAAYGCNAARMGNTGGTTYGAYCCNTCNYTNYTNACN ATHGAYTAYYTNTCNGGNTTYGTNGAYGTNCCNGAYGARAAYGARGGNTTYAARATHATG GARGTNAAYGCNCARTTYCARGTNAARTCNAAYTAYAARYTNGARGTNCCNGCNYTNTTY ATHCARTGGGARGCNGCNGTNTCNGAYTCNGGNGAYYTNGTNATGACNYTNTCNGGNYTN TGYGAYMGNTGGGCNAGYYTNAAYACNCAYGGNMGNATHATHTTYATHTGY--------- GAYGGNAARAARGAYTTYAAYYTNGGNAGYAARGARAARAGYATHYTNCAYMGNAAYYTN AARCARTTYGCNATHAARGGNCAYTAYCCNGTNTAYGTNGTNAARACNGCNAARACNAAY ATHAAYAGYTTYTGYGTNCCNCCNCARCCNGGNATHYTNGCNTTYYTNCARACNCAYCAY YTNATHGAYYTNCARGCNAARCAYTCNGTNTAYGTNTTYGARACNACNGAYCAYATGAAR ATGGCNCARGCNGCNGGNGTNAARCAYGTNAARAGYAGYAARGCNTTYAARCAYCCNGAR AARGTNYTNAGYAGYYTNTGYATGAAYCCNAGYGTNCCNACNATGYTNAARGAYATGAAR GTNGTNAARGGNGGNGAYGAYGARACNTCN------TGYATHCCNATHYTNGAYAARTCN AARGAYAGYGTNGAYGARGARTTYGTNTCNCAYTCNTAYCARGAYGGNYTNGARGARCAR ATGTTYTCNCCNAGYACNGCNGAYYTNTTYMGNATHCARGARAGYTTYGCNAGYCAYGTN ACNCCNATHGAYATGCCNGGNAGY------AARATGGTNACNCARGARTTYGAYGAYAGY ATHACNGTNTCNAGYAARGCNAARMGNCARGTNGARAAYATGAARAARAGYTCNTCNYTN CAR---------AAYYTNCCNGTNTGGATGAARAARMGNYTNAARMGNAARTCNACNGAR TCNTCNYTNTCNGGNYTNGARAGYGAYGARCARGARYTNTCNTTYAARTGYTCNAARACN GTNTAYATHATGAGYGARAARGARYTNAARGAYATHGCNGTNCARGTNATHAARCARGCN GGNAARGCNTGGYTNGGNAARGGNMGNTCNTGYGGNCCNCARTCNATHMGNGTNYTNAAR CARTGYGTNMGNACNGCNGCNGGNGCNAAYTCNCAYTAYGTNYTNYTNCCNGARGTNCCN CCNGAYAAYGCNGARACNAAYGCNGTNATGMGNATHGAYCARYTNCCNGARTTYTCNCAR ATHTCNCCNAAYAGYTGYATHACNGCNTGYGCNAARYTNGCNATHGARTAYGARACNAAR YTNGARAARCAYGCNAAYATHYTNAARGAYCCNAARTTYGARAARACNTTYGARAAYGTN TAYCAYCCNYTNGARGARATHGCNGTNCCNATHAAYACNGCNTGGGCNACNGTNMGNAAY YTNCAYTAYGTNGCNGCNAAYGAYGAYTAYMGNAARGCNTTYTCNAARGTNCAYCCNCAR GTNGARMGNGTNAARAAYGARMGNTGGGTNAGYCARCCNYTNTAYTAYTCNTTYAARGAR YTNGARTCNAAYAGYGGNAAYYTNACNGAYTAYCARAARMGNYTNGTNAAYYTNTAYYTN YTNGARGGNAARYTNAAYGGNGTNCAYYTNTCNGCNGARGARAAYTCNAARYTNATGGAY MGNYTNAARYTNATHTCNAARGARAGYCARAAYTTYMGNAAYAARGTNMGNATHTGYACN GAYATHTTYACNCAYGAYGTNACNAAYTTYAAYGCNATHGARGARATGCCNTGGCCNYTN YTNGCNCARATGTCNAARGAYAARTCNAAYCCNACNMGNGGNCCNTGGMGNGCNACNYTN CARCCNGCNGTNTAYCARGCNATGATGACNTAYTGYAGYCAYMGNYTNACNMGNTGGAAY YTNTGGAAYGCNTAYCAYAAYMGNGCNTCNCAYTCNCAYGCNGGNCARTAYYTNAAYAAY AAYAARYTNATHGARAGYYTNMGNTCNTAYMGNTCNGAYGTNGCNAGYATGYTNGGNTAY GAYAAYTTYGCNGARATGTCNATGGARACNAARATGGCNGAYTCNGTNGARAGYGTNYTN GGNATGATHGARACNYTNMGNGCNMGNTAYGCNCCNGARGTNTGGGARGARATGGCNCAR YTNCARCARTTYGCNACNTCNGARGGNTTYGARCAYACNYTNGARATGTGGGAYATHGGN TAYTGGMGNMGNMGNCAYMGNGAYCAYYTNTAYAGYYTNGAYAARGARGCNGTNAARGAR TAYTTYCCNGTNAAYTCNGTNYTNYTNGGNYTNTTYGAYYTNTGYACNAAYYTNTTYGGN GTNAAYTTYGARGARGTNACNCCNGARGTNGARGTNTGGAAYCCNGAYGTNMGNTTYTTY AAYGTNYTNGAYGAR---AAYGGNCARCAYATHAGYTCNTTYTAYTTYGAYGCNTTYGAY MGNCCNGGNAARATHTCNTCNGGNTAYATGGAYYTNGGNMGNGAYAAYAGYGTNCAYGTN GGNACNTGGCCNTAYTCNTAYYTNTGYYTNAARGTNCCNMGNCCNAARTCNGCNTCNGAY CCNATHYTNATGMGNTTYGARGAYGTNGARATGYTNTTYACNGARTTYGGNCAYGGNYTN CARCARATGYTNACNAAYGTNCCNTAYAGYGARATHGCNGGNCARAARAAYATHGARTGG GAYGCNGTNCAYGTNTGYGCNAARTTYATGAARCARTGGYTNACNGTNCCNAGYGTNGTN AARAGYYTNAGYGGNCAYTAYAGYACNGGNGARCARATHCCNGAYGAYATGYTNGCNACN ATGYTNAARGCNTCNCARCAYTGGAGYAAYTTYGAYATGATGTAYCARYTNTAYGTNTCN GCNTTYGAYATGGARATHTAYATGACNAARAAYCAYTGGCAYAGYGTNATGMGNAAYYTN TGGGARAAYTTYGTNCCNYTNTCNYTNGTNGARGARGAYAAYYTNCCNTGYTCNATGYTN CCNATHTTYTGYGARYTNTAYCCNGCNGCNTAYTAYTCNCAYCARTGGTCNCARATGATH GCNTCNGAYYTNTTYTCNGCNTTYCARGARGARGGNYTNGARGAYCARGARAARATGAAR GCNYTNGGNMGNMGNTTYMGNGAYACNTAYYTNTCNYTNGGNGGNGGNGTNTCNTCNAGY GARGTNTTYMGNCARTTYMGNGGNMGNGAYCCNTCNACNCARGCNYTNCARCCNATGGAR AAYAAYAAYGCNATHGCNGCNAARCCNGARYTNGAYGGNGARGCNAARATHGARAAYGTN AARCCNACNGCNGAR------GAYAAYTCNMGNAAYMGNGGNTAYMGNTAYAAYAAYMGN MGNMGNCARATHMGNMGNGAYGTNAAYCCNGARGAYGARACNGGNAARGCNGCNATHMGN MGNAARATHTGGGAYAAYYTNGARGAYAAYAAYYTNGTNTCNGCNCCNMGNCCNTGYCAY TAYMGNGTNCCNAAYTTYGARGGNGCNACNGARGCNGCNGAYMGNYTNACNTCNYTNGAY GTNTTYAARAAYGCNMGNACNATHAARGTNAAYCCNGAYAARGCNCARGARCAYGTNMGN TTYYTNGTNYTNGARGCNGARAARGARYTNGTNYTNYTNTAYCARAAYCARAARGARYTN ATGGTNCCNACNCCNGARYTNAARTCNGGNYTNYTNAAYMGNGTNGTNCCNCCNGARGGN TCNAAYAARGARGARYTNMGNCAYTGYTGYACNACNCARGGNGTNAARGARAAYAGYAAR GARATHGGNGTNGAYGAYAARGTNACNYTNGAYYTNATHGTNGTNGGNAGYGTNGCNGTN TCNMGNAAYGGNTAYMGNATHGGNAARGGNAARGGNTAYGCNGAYYTNGARTAYGCNATG ATGMGNACNYTNGGNGCNGCNGAYGCNAAYACNGTNGTNGTNACNTCNGTNCAYGAYTCN CARGTNGTNGAYATHCCNGARGARYTNGTNGAYGARCAYGAYATHACNGTNGAYTAYATH YTNACNCCNACNGARYTNATHAARACNAAYTGYAGYMGNCCNMGNCCNACNGGNGTNACN TGGAAYCAYYTNGARGTNAAYAARTTYTAYCARATHCCNGTNYTNMGNCARYTNMGNAAR AAYGARMGNGAYGAYGGNAARGAYGTNYTNYTNAARGAYCARAARGARGARGAYGARGAY CCNGTNGAYGCNATGGARCCNCCNMGNCCNMGNMGNTAYGTNMGNTAYTAYCARAAYGCN GGNGGNTTYMGNGGNMGNGGNMGNCCNTAYGGNGGN---TTYMGNMGNGGNAAYGGNMGN MGNMGNCAR---TAYGGNGAYAAYGARGAYAAYAARGARAAYYTNGARGGNGGNGARGAY TCNGGNGCNGAYGGNGAYAAYGARGGNMGNGGNAGYAGYAAYMGNCCNCCNGCNMGNGGN AAYTAYMGNAAYMGNMGNTTYMGNMGNGGNGGNGGNGGNAARATG---MGNGCNTCNGAR TCNGARCAYAGYGAYGGNGCNGTNGAYGGNAAYMGNGARGAYGGNGAYGAYMGNCARMGN CARMGNMGNTTYAAY---AAYMGNMGNMGNTTYAAYCCNAAYAAYGAYMGNMGNMGNMGN TTYGAYGGNCCNMGN------MGNGAYAAYMGN---MGNGAYGAYCAYTCNGGNAGYGAY GGNGARCARAARCAYTCNGGNGAYGARGAYGGNGARGGNMGNMGNCCNCARMGNCARMGN TAYMGNACNAAYCCNGARGCNGTNGTNTTYGTNGGNGCNYTNTCNMGNAAYYTNMGNGTN AGYGARYTNAARACNGARYTNMGNAARGARAAYGTNAAYCCNATHMGNYTNYTNTGGMGN GGNGGNMGNGGNTAYGCNTTYYTNTTYTTYATGGGNACNGAYAGYGCNAARGARGCNGTN AGYYTNYTNGCNGGNMGNGARYTNAAYGGNMGNGARATGAARGTNGARATGGCNAAYATG GAYACNAARMGNMGNCCNMGNAAYGAYMGNGGNMGNGAYGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNYTNAGYTTYGGNATH GGNCAYTTYTCNTCNTGYCCNATHGCNMGNTAYCARYTNGCNTTYYTNYTNGTNYTNMGN GARAARYTN------CCNCCNTGYCAYGTNTAYGAYCCNGTNTTYTCNACNCARGARAAR ATHGCNYTNGARGAYYTNGGNTGYACNYTNATHCAYCAYAAYGARGARGGNAARCAYGTN TGYCAYACNCCNACNYTNGTNTTYATGCCNCAYTGYGGNAARGCNYTNTAYAAYAAYYTN GTNTGGGCNAAYYTNGCNACNYTNGAYAAYYTNGTNATHATHGGNAAYAGYTTYTCNMGN ATGYTNGARAGYACNCCNCAYMGNATHYTNAARCARACNGCNAAYTAYGTNATHAARGTN TCNCCNTAYGTNACNGARACNCCNYTNAARTCNTCNTCNTTYGTNCAYACNGAYGTNTTY AAYGAYYTNGCNYTNCAYAGYTTYTCNMGNYTNAARYTNACNACNGCNCCNGARGARTTY TGGGARGGNAAYGGNGARCCNGTNTAYGAYACNGARGARGTNGARATHATHMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARAARTTYAGYYTNAARAARGARGCNGTNCARGAYCARYTNGAYGAYGARGAYGAR GARATGYTNGARAARAARGCNGAYATHGARMGNMGNACNTCNTAYGTNGGNAARTCNATG AARATHYTNGARTCNCARGARGCNAARYTNGARGARMGNMGNAARAARTTYGCNGCNGAY AARGAYMGNYTNGARCARGAYCARGAYGAYGTNYTNGGNTCNAARGTNTCNAGYYTNGGN ACNGCNGARYTNGARMGNATGMGNGARGARMGNMGNCARYTNTCNCARGARYTNMGNGAR GARCARAAYGARYTNGAYMGNGTNAARCARGAYMGNAARTCNATGGARGGNGAYGTNACN MGNYTNAARATGGCNMGNGARCARCARAAYAARAARYTNACNGARATHMGNGARMGNGTN GARACNAARYTNAARGARTTYGARGGNYTNCARGAYMGNTTY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GTNYTNGCNCAYTTY CCNCCNGGNGAYTCNTAYGARATGAAYGGNMGNGTNAARGARYTNAARAARTCNGCNGAY AAYTTYAAYGAYAARGGNMGNTCNAAYMGNTCNGCNTTYYTNTTYGGNCAYGGNGAYGGN GGNCAYGGNCCNAGYGARGARATGYTNGGNMGNYTNAGYMGNTTYAARGAYTGYGAYGGN YTNCCNMGNATHAARATGAGYAGYTCNGAYGARTTYTTYTCNGCNATHGARMGNGARGAR ATGGAYATGYTNAGYMGNTGGMGNGGNGARYTNTAYYTNGARYTNCAYAAYGGNACNTAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARTAYATHAARAARTCN GARGARAARAGYTCNATGGAY------CARATHCARAGYGARYTNACNGCNYTNYTNAAR TAYCARCAYGARAAYATHGTNACNYTNTAYGGNTAYGCNYTNGAYGGNCCNGARYTNTGY YTNGTNTAYCARTAYYTNAGYAAYGGNTCNYTNGARGAYMGNYTNATGMGNAARAAYAAY ACNCCNGCNYTNTCNTGGGARMGNMGNYTNAAYATHYTNGTNGGNTCNTGYAARGCNGTN AGYTTYYTNCAYTCNATGGGNTCNCARCCNYTNATHCAYGGNGAYATHAARAGYGCNAAY ATHYTNYTNGAYAAYCAYYTNGARGCNAARTTYGCNGAYYTNGGNCARTCNMGNTAYGCN ACNAGYMGNAGYTCNAAYACNGGNMGNYTNACNCAYATHACNATHGCNGARTCNCARACN MGNCARTAYGGNACNGTNGTNTAYCARGCNCCNGARATHATHTCNGGN------TGYAGY ATGTCNATHCARTCNGAYATHTAYGCNATGGGNGTNGTNATHYTNGARGTNTGYAGYGGN YTNGCNGCNTTYGAYGTNGGNMGNAAYACNAAYAARTTYYTNACNGARYTNTTYACNAAY CAYATHYTNCCN---YTNMGNGARGCNGAYMGNGTNGARYTNTTYCARGAYMGNAGYCCN GCNGAYGTNATHYTNCCNGAYGTNTTYYTNTCNGTNYTNAARYTNGCNGGNMGNTGYATH CARAGYACNAARAARYTNMGNCCNAAYAGYGGNAARYTNYTNAARGGNATHAARCARGTN TAY--------------------------------------------------------- ------------------GGNAARGGNGTNACNYTNACNGAYCCNTGYAGYATHGCNAAR AARYTNCARAARGARACNTCNAAY------GGNATGAGYYTNGARGAYMGNATGTGYGTN GARCARTGGYTNGAYTTYAGY---------AGYGAR------------ATHGARGCNGTN AGYGAYMGNGAYMGNATHCAYGTNATGYTNAARGAYYTNAAYTGYTAYATGAARGAYAAR GTNTAYTTYGTNGGNTCNGAYYTNACNGTNGCNGAYGTNTTYYTNTAYCAYAGYYTNTCN TCNATHTTYATGAARYTNTCNTTYCARGARAARGARAAYYTNATHCAYYTNTCNMGNTGG TTYAGYCAYGTNCARAARGAYGAYAARGCNMGNCARTCNYTNYTNCCNGTNACNTTYYTN MGNACNATGYTNTAYACNGGNATHGGNAAYCAY--------------------------- ------------------------------------------------------------ ------------------------------AARATGATGYTNACNAAYGAYYTNACNGCN GCNGTNATGGARGARGCNAARGARAARACNGTNGAYYTNATHYTNTCNTAYCAYCCNCCN ATHTTYGTNCCNYTNAARMGNYTNACNCARAAYTCNTGGAARGARMGNATHYTNATHGAY TGYATHGARAAYMGNATHGCNGTNTTYTCNCCNCAYACNTCNTAYGAYGCNGTNGARGGN GGNGTNAAYGAYTGGYTNATHTCNGCNTTYGAYGTNGAYAARGAYTCNYTNTCNCCNGTN GARGCNACNGARTCNTTYGTNAAYAAYAAYACNCAYATHYTNGARGTNGARACNGARCAR TCNAAYTTYAAYGARGTNTGGAARACNGTN---GCNAARTGYYTNCCNAARGARACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARCAYCARACNGARACNYTNTGYATGTAYTGY YTNTCNTGYAARYTNCCNGTNTGYATGACNTGYGCNAARGAYGGNMGNCAYATGACNCAY GARGTNCARCCNYTNCCNACNYTNTGYAARTCNCARAARAGYGARYTNTCNCARAAYYTN CARTCNYTNTCNGARAARGCNAARTCNGGNACNGARTTYATHCARMGNYTNAARAARATG GCNGAYAGYGTNAGYGCNMGNGTNAARGCNCAYAAYCAYGCNGGNGARAGYGAYTAYAGY GAYGTNGTNAAYYTNCARACNGCNGARTTYAARMGNACNGTNCARAAYAARAARACNTTY GTNTGYCCNAARGCNTCNGAYTGYACNGTNAAYGCNGTNAAYMGNAARAARTGYCCNGCN TGYMGNTTYAARMGNTGYYTNAAYATGGGNATGAARYTNGARGCNATHMGNCARGAYMGN ACNMGNGGNCCNGGNCCNTCNAARTCNCAYMGNAAYYTNGTNGCNATHYTNAAYCAYAAY GCNCAYAARCARACNCCNAGYCCNGGNAGYCCNGTNATHCCNGARYTNYTNMGNGAYATH ATGAAYYTNGARCCNYTNYTNAGYGAYGAYGAYATHCCNCCNGAYTCNATGATGGAYAGY GCNTTYCCN--------------------------------------------------- ------------------------------------------------------------ ---------------------------------------ATGGAYYTNYTNMGNTCNTGG ATHTAYGGNCAYGARAGYGAYAARACNACNAGYGGNATHTCNTCNGGNCARGAYGARAGY GAYGAYAARAARYTNGTNAAYGTNCAYCAYGCNGAYGARGAYTCNTCNAARYTNMGNCAR TTYATHYTNAARATHGTNCCNYTNCARTCNGGNGAYTGYYTNGGNTGYAARYTNGTNGGN ACNTCNGTNATGGTNGCNAGYGGNATHATHGTNYTNACNTCNACNATGGCNGGNMGNAAR MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------TTYCAYYTNAAYAAYCAYCARGCNAAYMGN AARYTNGGNATHTCNTGGAAYGGNGARGCNYTNGARCAYACNACNTCNCCNGTNTAYYTN GGNGTNACNYTNGAYMGNACNYTNTCNTTYGCNCARCAYATHAARAARGTNAARGCNAAR GCNGCNACNMGNAAYAGYCCNYTNGGNAARYTNACNAAYACNAARTGGGGNGTNGAYCCN AARACNYTNMGNACNACNGCNYTNTCNYTNTGYTAYTCNACNGCNGARTAYTGYTCNCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARCCNCCNACNAAYYTNGCNGARTTYYTNGAR GCNGARGGNYTNGARGAYTGGCCNYTNCCNATGAGYYTNGARGGNCCNYTNGAYATHAAR TCNGARGGNYTNTTYATHGGNAAYCARGAYGAYATHGCNGAYATHYTNAAYGARGCNGCN CCNYTNGGNYTNAAYATGYTNGARGCNATGGARGAYMGNYTNTCNGCNYTNGARGAYAAR ATHAAYYTNTAYGCNGAYCARATHGTNACNGARGARAARMGNCCNTCNMGNYTNGCNGAR MGNYTNTTYCAYTCNCCNACNAARACNTTYATGACNGAYATGTCNGAYTCNGAYGCNYTN AARTCNCAYMGNAGYTCNAARGGNCAYMGNAGYGTNGAYYTNATGGAYACNATGATGGAR ACNMGNAARMGNAGYYTNGAYTAYTAYATHTTYCCNGGNTTYGTNMGNGGNGARTTYATH GARYTNCCNGCNCARYTNGARGCNCCNCCNATHYTNCAYMGNATHACNAAYGCNCARGAY TTYAAYTCNGGNTTYAARAARTTYTGGAARAARYTNTTYYTNTCNGARGCNTCNTCNGCN GTNYTNCARGAYGCNTTYTGGTGGATHTTYYTNGAYATGTTYAAYAARACNGARGGNTTY GTNGARGAYAARGAYTGYATHTTYGAYMGNATHGCNGAYAGYTAYGTNGCNYTNTTYACN AGYATHAAYACNGAYGTNAARGAYAARTTYYTNTCNGTNTAYCCNAGYTGYYTNTCNCAR GCNYTNTAYCAYACNTAYMGNGARGCNTTYCCNGARTCNAARTGGMGNTTYGAYGARACN TTYAARCARTAYYTNGTNAAYYTNGTNTAYGARTGGGTNACNGGNYTNMGNCCNGTNCCN GGNGTNTGGAARACNTGGAGYGARGARGGNYTNGAYGGNAGYCARACNAGYMGNGARAAY GARACNGCNAARAARATGYTNGARGCNGCNGCNYTNAAYAARAARGTNGARYTNAGYYTN GAYATGGARTCNTTYGCNAARGTNATHGAYAARYTNGGNATHGARCCNGARACN---CAY CARGGNAAYYTNTCNMGNGARYTNACNAARATHACNAAYMGN------YTNTCNGTNCCN TCNMGNGGNAARGCNACNYTNGGNAARCARGARTCNCAYCARATHGGNCCNGGNCCNGAY TAYGARMGNGTNAARTTYAAYACNTCNGGNMGNAGYCCNYTNATHGCNCAYTAYYTNCAY ATGMGNCARYTNMGNAGYTAYAARCARCCNGGNATGAARGTNMGNMGNACNGARATHYTN AARYTNCCNCCNGAYGGNCCNACNTAYCARCARTTYATHGCNAAYACNGTNAAYAARGCN GARTCNYTNGARMGNGARTAYACNMGNATHTGYGARCARACNTCNAAYGCNATHATGGAY YTNGARMGNCAYAARMGNGAYTCNAAYMGNGARATHGCNGARYTNCARAARGCNYTNACN AAYGTNAARAGYATHCCNGARMGNMGNTCNYTNATGGAYAARATHTCNGARTAYAARGAY YTNGTNATHAARGARAARCCNYTNYTNGAR------------------------------ ------------------------TAYGARAAYYTNMGNGCNACNTGYCCNTGGAARTGG ACNMGNGAYACNGGNTAYGARGTNTAYCCNMGNTAYCCNATHGARGCNGARTGYYTNTGY TCNAGYTGYGTNACNGCNCARACNATGGARTGYAARMGNCARTAYMGNGARTTYAAYTTY TAYYTNAARTCNGGNTGYCARGGNGAYAARCCNGTNTTYMGNGCNGGNGTNTTYAAYYTN ACNGTNAGYTGYTTYTGY------------------TAYGAYCCNAAYTAYTTYTCNYTN CCNCAYCCNGCNTTYGGNGCNYTNACNGTNATHYTNATGGTNTAYYTNGCNGTNACNACN YTNTCNCCNGARAGYYTNCCNGARTTYATHTGGCCNTTYGCNCARTTYGGNAARTAYATG GGNACNCARCARTTYAAYGTNTGYATHGGNTTYTGYGTNTTYACNYTNATHGCNCAYAGY ATGGARGCNGCNTAYACNGGNAARGTNTGYCARGAYMGNMGNTAYACNGCNTCNAAYACN TTYAARTGGGCNYTNTCNACNTTYATHTTYGGNTAYCCNTCNYTNATHMGNYTNYTNTCN CAYAARCCNMGNTCNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNGAYATHACNGAYYTN ACNGAYGARAGYYTNAAYACNACNGCNGARGCNGCNGGNATGGTNGAYGCNCCNACNYTN GARAAYATHMGNYTNAARYTNGCNGAYATGGARMGNACNMGNGGNGARATHMGNCAYMGN TGGTCNTCNYTNAARTTYGTNGAYACNMGNCCNAARTCNMGNCAYCAYACN--------- ------AAYGARTGYCCNGARGAYCCNCCNGCNTTYGAYGTNTCNAARYTNACNMGNTGY CAYGCNTAYGARGARCAYAAYCAYCCNATHAAYAARGAYTGGTCNGARGARCCNYTNYTN TTYACNAARCCNMGNCCNGARAAY------GCNGGNCAYCAYMGNYTNACNATGGTNAAY ACNACN------CARGCNACNACNGAYCCNCCNGGNMGNCARCARGTNACNYTNAAYCCN GGNACNYTNGAYMGNATHYTNGARGAYMGNGARMGNYTNGAYGARMGNYTNMGNAARCAY TCNCAYCAYCCNACNGGNAARTTYGAYCCNTGGAGYYTNGTNGARGARATHTCNGARGAR ATHYTNGGNGARTGYYTNCARGARGTNTCNGARGARGTNGARAARGTNAGYGARGARATG GCNAAYCARATGTAYAARTCNGARTTYATGGTNACNGGNMGNCCNTCNGARACN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARATHATHGGNAGYCCNYTNTTYAARTCNCCNCAYAAYGAYTTYTTYYTNCCNGTN GCNCCNACNTTYATHTAYAAYACNGCNCAYACNTAYAARTCNACNGARACNGTNCAYCAY ATHYTNACNTTYYTNGCNTCNMGNTCNAARYTNGAYATHAAYGARATHYTNGAYATHYTN GAYGARGAYGGNTTYTCNGCNYTNCAYYTNTCNGTNATHAAYGGNGAYGTNAARGTNGTN AARATHYTNYTNGARYTNGGNTCNAAYTGYAAYAARNNNTCNCARAGYGGNAAYACNGCN YTNTCNYTNTCNATHGCNTAYGARTAYTAYTAYYTNGTNCCNYTNTTYYTNCAYAARTCN GAYGTNAAYACNCAYGAYTCNGAYCAYGAYACNCCNYTNATGTTYGCNGCNTGGAAYAAR GARCCNAAYATHYTNTCNGCNYTNATHCARTAYGGNGCNGAYGTNAAYAARGTNAGYAAR CAYGGNAGYACNGCNYTNTGGAAYGCNGTNTAYMGNTCNTCNCCNGARTGYGTNYTNACN YTNYTNAGYCAYAAYTCNMGNACNGAYGTNGCNTGYGARGGNACNCAYYTNTTYYTN--- GAYGARAAYGAYTGYAAYCAYAAYCARGARGTNGCNAARATHTAYCCNGGNAAYAARMGN TCNYTNYTNTGGGTNGCNGTNGAYMGNATHGGNGTNGARGAR---AGYYTNCARGTNYTN TCNATHYTNATHGARGCNGGNTAYGAYGTNACNAARGARTGYTGGYTNAAYGAYAARTGY CCNAARYTNTTYCAYTCNAAYCCN---------------------CCNYTNCARTGYYTN YTNCAYTTYYTNAAYAARMGNCCNCCNAGYYTNAARGAYYTNTGYMGNAAYAGYYTNMGN YTNCAYCAYMGNYTNAGYAAYYTNCAYTTYCAYGAYTGGATHCARGGNYTNGGNYTNCCN TCNATHYTNAARGAYTTYTTYATHYTNTCNTAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNACNYTNTTYYTNYTNGCNYTN------------ ---------------GTNGGNGCNTTYGCNYTNGTNAGYTGY------------------ ------CARTTYGCNGARMGNGARMGNGARMGNAGYMGNGAYMGNAGYMGNGARMGNCCN TCNGARGGNTGYATGGAYAARGTNATGGAYATHTTYTTYYTNATGGAYTCNTCNTCNTCN ATHTAYATHAAYGAYTAYATGACNCARCAYMGNTTYGTNMGNGAYGTNATHGCNMGNTTY GAYGTNAGYCCNGARAGYACNMGNGTNGGNATGYTNACNTTYAGYGAYGAYYTNGARMGN CCNGTNYTNGGNYTNGAYMGNTAYACNAGYAARAAYGAYYTNYTNGARAGYATHTCNATG CARAAYYTNCCNTAYMGNACNGGNGARACNAAYACNGAYYTNGCNATHMGNTAYGTNMGN CARATHAGYGAYTTYMGNCARGAYATHACNAARGTNATGGTNGTNATGACNGAYGGNGGN TCNMGNTCNMGNGGNTCNACNGCNMGNGARGCNGARYTNGCNMGNAAYAGYGGNTTYTAY ATGTTYGTNGTNGGNATHGGNCARTAYYTNGARGARAAYGARTGGMGNTCNATHGCNAGY GAYCCNGAYGAYAGYTTYATHTAYAAYATHACNAAYCCNMGNTTYATGGAYGAYGTNAAR TTYTCNYTNCCNCCNMGNGCNTGYGCNYTNCCNCCNATHATHGTNGGNGGNTCNTGYGAY GTNMGNGARYTNTCNGARGTNTAYTTYGTNGCNTCNMGNAGYGCNAGYGAYATGGCNATH GAYYTNATHGAYACNTTYAARMGNMGNACNMGNGAYCARMGNGAYYTNATHMGNTTYAAY TAYATGATHGARGCNTGYGGNTCNATHACNAAYGCNGCNYTNGAYGAYGCNGARGTNGAR ---TGYGAYMGNTTYGCNCCNMGNAGYGGNGAYACNTCNGAYTCNGTNGCNGCNYTNTTY TCNCARGCNMGNCARATHGCNMGNMGNAAYAAYGGNGGNMGNAAYTCNAAYCARGTNGTN GTNYTNTTYGCNGAYGAYGARACNATGAAYYTNGCNMGNTTYGAYTGGTCNAAYGAYGCN MGNAGYGCNGARAAYYTNGARGGNATHAARGTNATHGTNGTNGAYYTNGGNYTNMGNACN TAYMGNAAYTTYGCNMGNMGNATGGTNTCNGCNACNAAYAAYATHGTNAAYTAYYTNGAR GGN------------CARTCNAGYTCNCARMGNGCNATGATHGAYACNACNTGY------ ---------------------------------------------CCNAAY--------- ---------GAYGAYTTYGARAARGTNGAYGCNCCNGGNGGNGGNTTYGAYATGACNGCN TCNTCNGGNGCNTAYGARTAY------------GAYGTNGAYCARGAYGCNGARATHTCN ACNACNACNGAYGCNGAYGTNGCNGGNGARGARGARGCNGARGCNGAYMGNTTYGCNATG GGNTCNCARGAYGARATHGCNCAYCCNTCN---------GARCCNYTNATHTGYTGGGGN GAYGAR---------------------------------GARGAYGARGTNACNTCNCCN CARGTNCARCCNTCNGCNCCNGTNCCNGARCCNGARAGYAARGARCCNYTNYTNAAYTTY ---GAYGAYACN---CCNTCNGGNGAYGAYTAYATGCARTCNTTYAARCCNTCNGTNCCN CCNACNAGYACNACNCCNGARCCNAAYTCNAGYAAYCCNYTNCCNTCNTCNYTNGAYGAR TTYATHGTNCCNAARACNGARGARAGYGARAGYGARMGNATHAARGARGARAGYAARCCN GTNTCNGAYCARACN------ACNGTNGARGCNGCNGARGGNTCNTGGYTNAARGGNGTN GAYCCNMGNGARGAYGAYGTNGGNGAYGCNYTNTCNCARGCNYTNATHGAYYTNATHTAY TGGMGNGAYGTNAARACNACNGGNYTNGTNTTYGGNGCNATGYTNGTNGTNYTNYTNTCN YTNGCNATHTTYTCNYTNYTNAGYGTNGTNGCNTAYYTNTCNYTNGCNGTNYTNACNGTN ACNTTYAGYTTYACNGTNTAYAARAARATHATGGGNGCNGTNCARAARTCNAAYGAYGGN CAYCCNTTYAARCARYTNATHAAYATGGAYATHGCNYTNAGYGARGAYAARYTNAARAGY ATHATHCARAGYTTYYTNAARAAYGCNAAYTGYACNATHAGYGARYTNMGNMGNYTNTTY YTNATHGARGAYATGGTNGAYTCNATHAARTTYGGNYTNYTNYTNTGGGTNYTNACNTAY GTNGGNGGNTGGTTYAAYGGNATGACNYTNGTNATHATHGTNGTNATHGAYATHTTYACN YTNCCNAARGTNTAYGARACNTAYAARGTNCARATHGAYAAYTAYGTNGGNYTNGCNAAR GCNCARATHGAYAAYGTNYTNAAYATHGTNCARAGYAARYTNCCNTTYYTNAARAARAAR GARAARGCNCAR------------TTYACNTGGYTNAGYAARTAYGGNCCNGARTTYCAY ATHMGNGGNGARCARGTNCARATHATHTCNGARCCNMGNGARTTYTAYGARATHYTNAAR GTNAARACNMGNAARGCNAARAARMGNGTNACNTTYGCNTCNYTNTAYYTNGGNACNAGY CARYTNGARAARGAYYTNGTNTCNAGYATHGAYGARGCNTGYCARGCNGCNGCNTCNACN GGNTCNTCNGAYYTNGARGTNAAYGTNYTNYTNGAYTTYACNMGNGGNTCNMGNGGNGAR ATHAAYTCNMGNACNATGYTNMGNCCNYTNATGGARAARTGGCCNAAYGTNAARGTNGCN YTNTAYCAYACNCCNGAYYTNMGNGGNTGGYTNAARAARGTNGTNCCNGARMGNTTYAAY GARACNATHGGNYTNACNCAYATHAARGTNTAYYTNTTYGAYGAYAGYTTYATHATHAGY GGNGCNAAYYTNAGYTAYGAYTAYTTYACNAAYMGNCARGAYMGNTAYATGYTNTTYAAY GAYTGYCCNCAYYTNGCNGAYTTYTTYCARCARYTNGTNAARTCNGTNATGTCNTTYTCN YTNCARYTNCAYCCNGAYAAYTCNYTNCAYYTNGCNGARGAYTGGAAYATHCAYCCNTTY YTNGAYTCNGAYAARGGNYTNAAYTTYAARYTNGCNGCNMGNGARAARATHCARGAYTGY YTNAAR---------------TCNCAYATHTAYTCNCAYGAYGAYATHGTNGAYGARGAR AARGARATHTTYCAYATHCARGAYTAYMGNGCN---------GAYACNGTNGTNTAYCCN YTNATHCARATGGGNCCNTTYGGNGTNCARAAYGAYGARAAYGCNACNATGGAYYTNYTN YTNMGNTCNCARCARCCNGAYYTNGTNYTNYTNACNTCNGGNTAYTTYAAYYTNACNGAY GARTAYGCNGAYGTNATHGTNAAYGAYGCNGAYGCNAARTTYAAYATHYTNATGGCNTCN CCNAARGCNAAYGGNTTYYTNGGNGCNAARGGNGTNGCNGGNGCNATHCCNTAYTCNTAY ATHTAYYTNGCNCAYAARTTYTAYAAYAARGTNACNAARGCNGAYCARGCNTAYMGNYTN CARATGYTNGARTAYGARMGNGARGGNTGGACNTTYCAYAGYAARGGNYTNTGGTAYTAY YTNAARAAYGARCCNYTNCCNMGNYTNTCNYTNATHGGNTCNCCNAAYTTYGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNTCNTCNCAYAARACNCCNGGNGAYAARTCNGGNMGNYTNTCNGCNTAYGAYTTY CCNGAYGAYAGYCCNGAYGARGAYCCNGTNAAYTAYATG---------GCNGCNMGNTCN ACNMGNAARTGYCCNGTNGAYAGYTCNGARAAYAARACNGCNTCNTGGGTNGGNCCNGAY ACNCARGGNGCNGAYGAYGGNAARGGNGAYAARAAYGARGCNCARACNYTNGAYACNTTY CCNGAYAGY------------------------AARCCNAARTCNMGNTTYGGNAGYMGN GTNAGYAGYATHGARGCNGAYTCNGGNATG---------TCNTCNGTNGAYAGYACNMGN CCNGAYAAR---GCNCCNGAYGCNGGNGARGTNGAYAGYTCNACNTCNTCNTCNTCNCCN GCNGAYMGNYTNAARATGGGNGCNAGYAAYCCNCARACNTCNGCNGAYTCNGGNCARACN GTNGAYTCNTTYTCNCAR---GGNAGYCARGAYTCNYTNGTNACNAGYGARGAYGTNGGN TCNGGNCARTCN---------------------------GTNTCNAGYCCNTCNTAYTCN TCNGGNCARCCNGTNGTNTCNAGYATGATHMGNGAYCCNGAYCARACNACNATGTGYTCN MGNGAYCARGARCCNACNCCNYTNYTNTCNGCNCARTAYGARACNYTNTCNGAYGAYGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGTGGMGN TCNCAYACNTTYMGNAARGGNMGNCARATHYTNACNTTYGCNCARMGNCARYTNGCNACN GARGCNGGNGGNGCNAGYGCNGCNCCNYTNCCNCCNCCNCCNCCNCCNAARTCNGGNGGN TTYGGNYTNATHAARTTYYTNGGNYTNGGNYTNCCNYTNGCNACNGGNGGNATHGTNGGN TAYGCNTGGTAYGAYAARGAYTTYMGNAARCARYTNGARGAYAARGTNCCNTAYGCNAAR GARYTNYTNGARAAYGTNYTNCCNCCNAAYGARCCNGCNGCNCARGGNAAYTTYCCNAAR AAR------------------------------------------GTNCARATGCARGAR AGYGCNCARTTYCCNGCNCCNATHTAYGGNTCNAARGCNCCNCCNAARCARGAYYTNTCN TCNGCNATGGARAARCARGARAARGTNGAYAARGTNAARACNGTNGARCARCARYTNMGN AAY---AARGARATGGARGARAARGCNGAYAAYGCNGCNYTNGARGTNGTNATHGAYAAR YTNYTNGARTCNGGNCARAAYTGGGTNTCNGARGCNGCNMGNGCNCARATGGAYGTNGCN AARGCNACNAARAAYCAYAGYGCNYTNYTNAARAARGCNATGGAYGAYTCNTCNGAYATH YTNGCNAARGAYTCNGARTGGGARGCNGTNACNATHGCNTTYAARGARMGNGARATHGCN GTNACNMGNGCNAAYGARYTNGTNGAYCARGCNAARMGNAGYATGGAYAARYTNAARAGY GTNYTNGAYGARGCNAARTCNAAYAARGTNACNATGAARAAYAARGCNATHTAYCCNGCN ACNAARAARATHGCNGCNYTNACNAAYGAYATGACNGCNGCNGGNTCNCARGTNMGNCAR GCNGAYGCNGAYGCNAARGTNATGYTNAARTAYAARGAYYTNGTNGARAARGGNMGNMGN CARTTYCARYTNGARYTNGARAGYYTNGTNCCNGAYGTNAARCCNGGNGGNAARAGYMGN AARYTNACNGARGARGARYTNAAYGCNYTNATHGCNCAYGCNCAYMGNMGNATHGARCAR YTNCARAARCARATHGCNGARCARYTNTCNATGGARMGNAARMGNYTNTCNATGGCNYTN GAYGCNCARAARGARGARAAYAARAGYATHACNGARTCNGCNGTNGARGAYGARMGNACN MGNTCNYTNAGYGARTTYGAYYTNGARAARCARAARATGGARATGGARTTYATGGTNCAR ATGGARYTNGAYGTNMGNMGNCARYTNAGYMGNCARGCNGCNGCNCAYAGYGAYCAYYTN AARGAYGTNYTNGCNGTNCARGARCARGARATGAAYAARGAYTTYGARMGNAARATGAAY ATHAARYTNYTNGARGARMGNGAYAARTTYCARGARGARACNTCNGGNTGGATHTCNMGN YTNAARGGNATHGARGCNGCNGTNGAYGCNMGNGCNGCNAGYGARAARYTNGCNMGNACN GCNCARGAYYTNTGGYTNGCNTGYATHGCNYTNAAYTCNACNATHYTNTTYGGNAAYGAR GARGARAGYAGYACNYTNGTNCCNYTNCARCCNCARGTNGARGCNGTNGTNAAYTCNGCN AAYAARCAYCCNTTYGTNGARACNGTNGCNAAYACNATHCCNCARGTNGCNYTNGAYMGN GGNGTNTAYACNGARAAYGAYYTNMGNGAYMGNTTYGTNMGNGTNTCNCARATHAGYMGN MGNYTNGGNYTNGTNACNGARTCNAAYGCNTCNYTNTAYAARTAYYTNGTNTCNTTYYTN CAYTCNTTYTTYACNGTNAAYAAYGTNGCNGCNTAYTCNGARAARGAYYTNGTNTCNYTN GAYGARATGGAYAAYTTYAARYTNGTNGCNAAYGCNCARTAYTGGATGGARAARGGNAAY YTNGARATGGCNGTNMGNTTYATGGGNCARYTNACNGGNGARTCNAARAARGCNGCNGGN GAYTGGATHACNGARGCNMGNYTNYTNYTNGARACNMGNCARGCNGCNCAYACNGTNATG ACNTTYGCNTCNGCNACNGGNYTNGCNGCNACNTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYGGNYTNAAYGAYACNCARGCNTCNYTNCCNMGNACN TCNTTYTCNGARGAYYTNAGYGAYGCNTTYGAYGAYATHGARGGNGCNACNGGNGGNGTN AGYYTNAGYGGNCAR---GAYAGYYTNGAYACNCCNTAYAGYAARATHTCNMGNYTNTCN GARTCNTCNTCNGAYTCNGGNTTYAGYGGNAARGGNGGNTTYAGYTCNTCNTCNTCN--- ---TCNTCNTCNTCNTAYTAYGCNGGNAGYCCNGCNGAYTCNACNATGGCNAAYAGYTCN ACNAAYTCNAAYGAYACNGARCAYGAYCCNCAYGGNTCNCARGTNYTNGCNCAYCARGTN GCNCAYAAYCAYACNTAYAAYACNYTNCCNGGNCAYGTNCCNMGNGARGTNAARAARTAY GCNCCNAARGARAAYACNMGNAARGGNCCNCARTGYMGNGAYGCNMGNAARGCNCARGAR ATGAARATHCCNTTYACNATHGAYCARATHGTNGARTCNCCNGTNGARACNTTYAAYGAY ATHYTNACNAARTAYAGYYTNAAYGARGAYCARYTNACNYTNATHMGNGAYATHMGNMGN MGNGGNAARAAYAARYTNGCNGCNCARAAYTGYMGNAARMGNAARGTNGGNGCNATHGTN ACNYTNTCNGAYGAYATGGTNGARYTNCARAARGTNMGNGAYMGNYTNAARGCNGARMGN ACNGARATGGARMGNGARACNMGNMGNATGAARGARAARTTYGGNCAYYTNTAYACNCAY ATHTTYCARTCNYTNMGNGAYGARCAYGGNGARCCNTAYGAYACNAAYMGNTAYTCNYTN CARCARTCNAGYGAYGGNAAYGTNTTYYTNGTNCCNMGNAAYATHAGYACNAAYGGNATG AGYAAYGGNAAYAGYAGYAAYAGYGAYAGYGGNCARAARAAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARTTYGCNCCNYTN GTNMGNGCNGTNTCNMGNGTNAAYAAYGCNMGNAAYATG---AGYGGNCAYGGNGTNCCN GCNCAYTTYAARCCNATHMGNCARATHTGYGARGARAAYMGNAGYCAYATGAAYTGYATG CCNGTNCCNCARGGNTCNTGGCARGARGCNTAYGCNGCNAARAAYTCNCARAAYAAYATG ATGYTNYTNGGNAGYYTNGCNGCNTGYATHGCNACNTTYGGNGTNYTNTAYTCNACNGGN TGYATHTAYYTNCAYGGNGCNCCNCCN------------------------------ATH AARGTNCCNCCNAARYTNAAYAARYTNGTNGCNGARAAYCAYGCNYTNYTNGARAARTGY GCNACNGCNAARYTNGTNAARAARATGCCNGAYGCNGAYGCNGCNCARAAYTTYATHGAY MGNYTN---AAYGGNCARAAYGARGTNAGYCCNGARYTNTGGGCNMGNGCNAARGCNATG ACNTGYYTNCARAGYCAYTCNYTNATGYTNAARTCNYTNCAYTCNYTNGARYTNGGNAAR YTNTCNGARGCNACNCCNTTYGARACNGTNTAYAARGGNAARAARYTNYTNGARTTYATH YTNTCNAARTTYGCNCARACNCARAAYGARGCNGAYTAYTTYTCNMGNGTNCARTTYMGN CAYGTNCCNTCNAAYGGNYTNACNTCNACNGTNGCNTCNTCNGAYACNGAYGTNATHATG TCNTCNCARGGNAAYGARTCNTCNGARCAYTGGCAR------AARGAYMGNATHGTNCAR GAYGCNYTNMGNTGYTCNAARYTNTGGACNCARYTNGARTTYGARAARCAYYTNTAYYTN GTNCARAARCAYYTNYTNTCNYTNTCNGARGCNGARTGGTGGGAYGTNYTNTCNAAYGAY CCNCARTAYTGYAGYATHTTYCARATGACNCAYAGYYTNYTNACNTCNAGYGGNGARTTY TTYCCNGCNATHGTNCAR---------------------TTYMGNACNGCNYTNGARGAR GCNAARCARMGNATHGTNMGNYTNMGNGAYGARAAYGAYATHAARGAYGAYATHATHGAR GAYGARMGNAARCAYMGNCARGCNYTNGARGARAARYTNGARAARTAYYTNGTNGAYCCN TAYACNAGYCCNGAYGTNAAYGAYGARYTNCAYCARMGNYTNCCNAARGCNAARAARAAR GGNYTNYTNGAYATGTCNMGNCCNACNCCNGCNACNACNTAYAGYCCNTTYGGNTCNACN AGYAGYCCNYTNTAYAGYMGNGCNACNGGNGCNAGYGTNGARTCNAARTCNYTNGAYAGY YTNGAYTTY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GCN AARATHAGYAAYAGYAGYACNYTNGTNCAYTGYATGGTNGCNGARCARYTNAAYAGYAGY AGYTGGMGNTAYMGNGTNATHGCNTGYAARATHYTNCCNACNYTNTTYGGNTCNATHAAY MGNGAYATHACNCARAARYTNTCNGARYTNATGTGGCAYGAYTGGCAYGTNGARGTNMGN AARGCNGCNGCNCARTGYYTNGGNAARACNAGYCAYGGNMGNGAYGTNCAYGAYGAYATH MGNGAYMGNATHYTNAAYGGNACNGARMGNACNAARATGGARGCNATHAAYAARYTNGGN CARYTNGGNATHATGACNGCNAARYTNYTNCCNGCNTTYYTNAARTGYTTYTCNGAYTCN TAYGTNTCNATHMGNTGYGARGTNTGYATHACNTGYGGNAAYYTNCARATHAARGARGAR CARGTNYTNGARCARYTNGTNCAYYTNGCNACNTTYGAYCCNATHTGGAARGTNAARGCN YTNGCNATHCARGCNYTNGGNAARATHGGNGARGARAAYGARGAYGTNAARGARTGYYTN YTNTGGGCNATGMGNTAYGARGARMGNCCNGGNGTNMGNGCNGARGCNTGYCAYTCNYTN GTNGGNYTNAAYATHCARGAYGAYGAYGTNATHGARATHYTNCARGAYMGNYTNYTNGTN GARTCNAGYCARYTNGTNMGNGARGARATGATHGARGCNYTNTCNGTNTTYGGNTTYAGY ACNTCNGARGAYATGGAYACNGTNGCNCARATHAARGCNGARGTNMGNAARYTNTGYACN MGNAAYATHATHGCNTCNCARATHATHGTNAAYGARAAYGAYGARACNAARMGNGARCAR YTNGGNMGNATGGTNTGYCARACNGARAARGAYATHGARACNYTNAAYGARMGNAARGAR ATHATHYTNMGNMGNATHMGNTCNCARGCNMGNAGYMGN------GGNGAY---AAYAGY GTNAGYTCNTCNCCNCCNCCNMGNACNTCNACNCCNYTNCCNMGNGTNAARATHGGNTCN GGNAGYAGYAGYACNACNCCNGARCCNGTNAGYMGNGAYGGNACNGTNTTYACNCCNACN GCNGAYAARGARYTNGARGCNATHYTNAAYCARGAYGARGAYGTNGARAGYGTNAGYGGN TCNACNAGYGGNAARTCNMGNCCNGTNACNGAYGGNTCNYTNGARYTNGAYGGNGARGAR GARGAYGGNGARGCNGARGGNGARAARGARGARGARAGYGARAARGTNATHTCNMGNATH ACNATHACNAARGTNGAYGGNGARGARGAR---------------------ACNGGNAAR AGYAGYGCNAAYAAYCARGGNAARATHCARYTNAGYATHCCNMGNAGYCARGCNGGNYTN YTNTCNCCNATGGGNTCNGTNGCNGAYTTYAARGGNTCNMGNYTNACNATHAGYCARTTY TCNGGNAARMGNTCNATHATHAGYMGNGAYAGYATGMGNGARMGNGARAARATGAAYGCN GARGTNAAYACNATHTAYGCNGAYYTNAAYGCNMGNTAYGCNAAYATGATHCARCAYYTN GCNAARATHGAYAARGGNYTNAAYACNAARGGNTCNTCNGCNGARTCNAGYAAY------ ---------GTNTCNAAYGTNGGNTCNAGYCAYATHGCNMGNYTNAGYCAYCARGARATH GTNGAYGARAGYATHCARTCNGCNMGNYTNGARAAYGARGARGGNGGNGARGARGARGGN AARGARGARGARGGNGAYGARGARGGNGGNACNGGNTCNGARGARAARTCNGAY------ GAYGAYGGNAARACNGTNGAYGAYCAYGAY---------------------------ACN ACNGARTGGAARTCNTTYGTNGARACNYTNTCNCAYGAY---AAYACNGARGAYATGACN ACNTAYCCNTTYAAYGARGARAAYCARAAYTCNCARYTNAGYACNGAYGGNAAYACNGCN YTNGAYTCNCARTGYGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARGARGARCARAARTAYYTNGCNTTYGCNAARGARGTNACN GAYGAYGTNYTNACNMGNGGNATHTCNACNGAYMGNGTNYTNCARAARGCNTTYGARAAY CAYATHGARMGNMGNMGNGGNGAYYTNGAYGARGAYMGNATGMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHMGNCCNYTNAAR---GARGAYGARCARYTNCAYCARATG ATHATHGAYYTNGCNGARTTYGARAARATGGGNGGNMGNGTNGARAAYACNCCNGAYGGN YTNMGNMGNGAYATHTTYGAYGTNCCNAARMGNTGYATHTGYYTNGTNGCNGARGAYAAR GAYATHGGN---------ATHYTNGGNTTYGCNYTNTCNTAYTAYGCNTAYTCNACNTGG CARGGNACNTAYYTNCAYYTNGARGAYYTNTAYGTNAARCCNGAYTTYMGNGGNAARGGN ATHGGNATGAARYTNTAYCARGCNACNGCNCARYTNGGNYTNGAYATGGGNGCNGCNMGN GTNGARYTNGAYGTNYTNGAYTGGAAYAARACNGCNAARGAYTTYTAYGARAARGTNGGN AAYGARGAYATHACNGARAARGARGGNTGGCAYMGNATGMGNYTNACNCARGAYAARATG GARAARTTYGTNAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CCNMGNGAYACNTCNTAYACNGAYGAYAAY GCNATHCARGARCCNGGNTCNATHACNAAYGTNGAYATHTTYTCNCCNTCNCARTCN--- GCNCCNAGYAARCCNAARAARAARAARAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CAYCCNAGYGTNAAYCCNAAYGCNATGGGNGGNYTNGGN AGYTGYGTNGGNGGNGCNTAYACNTCNYTNATHGCNTGGAARMGNCCNTCNATGAARTGY TTYGCNGCNATHAAYAGYTCNCCNTGGCCNACNGCNCCNMGNCARACNGTNGARGGNGAR YTNGTNGARGARMGNCCNATGATHATGAARAAYACNGARYTNATHGAYGGNGCNYTNTCN ATGMGNCCNYTNCAYCARGGNGGNAARCARACNYTNTTYYTNCCNTAYTGGMGNCAYGGN GCNAARGTNYTNCAYGTNCARGGNGARGAYGAYCARTGYATHGAYCCNGARTCNATHGTN GTNGAYYTNAARAAYATGCCNGARAARTTYMGNAARAAYGTNGARATHGTNMGNTAYCCN GGNGCNGGNCAYATHATHGARCCNCCNTAYYTNCCNYTNTGYMGNAARAAYTTYAAYAAR ATHTTYAAYGTNATGTTYYTNTGGGGNGGNCARCCNAARYTNCAYGCNCAYGCNCARATG GARAGYTGGTCNAARATHGTNGCNTTYYTNAARGARAAYYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GTNGAYCARYTNCARGGNAARYTN GGNGGNTAYGGNMGNTAYCARATHATHATHTAYTGYYTNYTNGGNATHGTNTAYATGMGN GGNTGYTGGCAYGCNYTNATHCCNATHTAYCARGGNYTNGAYCCNGGNTAYCAYTGYMGN CCNGCNCCNGGNCARTCNYTNAAYGARTCNGTNCCNGGNCAYACNGCNGAYGGNGTNTGG GTNTAYGAYAGYTGYAARCARTAYGTNAAYTTYTCNAARGGNAAYCARACNGARGAYTGY AARMGNGGNTGGGAYTAYGAYTTYGAYGAY---GAYCARACNTCNATHGTNTCNGARTTY TCNYTNACNTGYGARMGNAAYTAYYTNATHGARYTNTCNACNACNATHTAYATGGTNGGN ACNACNTGYGGNGTNATHTTYYTNGCNCCNGTNTCNGARMGNATGGGNGCNAARACNGTN ATGYTNGCNTGYYTNTGGGTNCARGCNGTNGTNGGNACNATHATGCCNTGGGCNAGYAGY ATHGGNGTNTTYYTNATGYTNAARTTYTTYATHGGNGTNTGYAAYATGACNATHGCNYTN TGYGTNGCNGTNATGATGCCNGARGCNTTYGAYGCNGCNCAYMGNGARATHCCNGCNATH GGNATHCARTTYTTYTGGGCNTCNGGNATHATGACNYTNTCNYTNTTYGCNTAYYTNYTN CCNGAYTGGAARCAYYTNCARYTNYTNATHACNYTNCCNATHAAYATHTTYAGYATHACN TAYATHTGGYTNATHCCNCARTCNYTNCCNTGGYTNATHTCNAARGGNAARYTNAARAAR GCNMGNMGNGTNATHCARMGNTTYACNGCNATHAAYAARYTNCCNACNATHCCNAAYYTN GAYYTNYTNYTNATGAGYTTYGGNGARGGNAARAARACNAARYTNGTNTCNGARTCNGCN CARTCNAAYTCNMGNYTNTCNGARMGNGTNTCNTCNGARGGNAGYGARAAYGAYACNAGY GGNCCNACNTAYAAYGTNYTNCAYYTNTTYAARGAYYTNTTYMGNGGNTTYYTNGTNTCN GARCAYAGYGAYGARAAYATHGARTTYTGGATHGCNTGYGARAARTAYAARGTNGTNAAR TCNCAYAARCARYTNGCNCCNYTNGCNAAYAARATHTTYAAYGAYTAYGTNGCNGTNCAR TCNMGNMGNGARGTNAAYYTNGAYTCNAARACNMGNACNTCNACNGARAGYGTNACNTCN AAYCCNAAYMGNCARACNTTYGAYGAYGCNCARAARMGNGTNCARGCNYTNATGGARAAR GAYTCNTAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATGCAYCCNTAYTAYTAYGTNCARTAYGTNCCNATHCCNYTNAARCARGAYYTNGAR ATGAARGTNAAYTGGGCNGCNTCNCCNAGYACNGCNCCNAARCARGAYACNAGYAARCAY TTYCAYGTNTTYGTNGGNGAYYTNAGYTCNGAYATHGARCARACNCARYTNMGNGAYGCN TTYTCNYTNCAYGGNGARATHTCNGAYTGYAARATHATHMGNGAYCCNGCNACNATGAAR TCNMGNGGNTAYGGNTTYGTNTCNTTYGTNAAYAARCARGARGCNGARGCNGCNATHGTN GCNATGAAYAAYCARTGGYTNGGNACNMGNCCNATHMGNACNAAYTGGGCNACNMGNAAR CCNYTNGCNCCNGTNATHAARGARAAYACNAARGCNYTNGCNTAYGARGARGTNTAYGGN CARTCNAGYTCNACNAAYTGYACNGTNTAYTGYGGNGGNGTNGCNAAYGGNYTNACNGAR GARGTNATGMGNAARACNTTYTCNCARTTYGGNACNATHCARGARGTNMGNGTNTTYAAR GAYAARGGNTAYGCNTTYATHMGNTTYAGYACNAARGARGCNGCNACNCARGCNATHTGY GCNGTNCAYGGNACNAGYGTNAAYGAYYTNCCNGTNAARTGYTCNTGGGGNAARGARTCN AAYGARTCNAGYCARACNAAYCARCARTCNCAYAGYCCNCCNGTNGTNATGGTNCCNTCN CARCARCARCARCCNATHGCNGCNACNCCNACNGCNGCNCCNTAYGGN---CARTAYTAY AAYATGAAYTAYTAYCAYGGNGCNCCNTAYGCNGCNGGNGCNCCNACNTAYCARAGYGCN GTNCCNGCNCARGGNCARTTYATHCCNGCNGCN---GGNCARTGGGGN---GGNTAYTCN AAYTAYCARGCNTAYGGNAGYATGAAYGTNCCNGTNGGNGGNTAYGCNGGNYTNCARATG CARCCNGGNGGNCARCARCARCARTTYAGYGGNCARGGNCARGGNATGGTNGGNTAYCCN ATGCARCARGGNATGGCNMGNTCNAAYGTNCARTAYGARGTNYTNCCNTCNGARGARCAR TGYGTNGCNGCNGARCCNGTNGAYATGGCNATGGTNATHCCNCCNCCNCARTAYACNGAR AAYGCNGTNATGGARCARGAYGGNGAYACNCCNGCNTAYGGNCCNGCNAARYTNCCNAAY TAYGTNGARGCNACNACNYTNCCNACNTAYGARGARGCNGARMGNAGYAARGTNGARGAR GAYGCNGCNTCNGGNGGNMGNAGYGGNGAYTGYGARTCNGGNMGNYTNACNACNATHGAY GGNGTNAAYGARGCNACNATHGGNACNGAYGGNATGTTYATHTGYACNTTYTTYATHTCN TTYYTNTTYAAYTGGYTNGGNTTYYTNYTNTCNYTNTGYYTNTCNAAYACNATHGCNGGN MGNTGYGGNGCNYTNTCNGGNYTNGGNYTNTCNATHGTNAARTGGGTNGTNATHGCNAAR ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNAGYGTNCAYACNGARCARGTNGTNAAYTCN GAYAAYAARCCNAARMGNTCNATHYTNTTYYTNCAYGGNATGMGNTTYTCNTCNCARAAY TGGYTNGAYATHCARTCNGTNTTYCAYGCNGCNAGYTGGGGNTGGMGNGCNGTNGCNATH GAYYTNCCNGGNTTYGGNAARACNAARGAYACNYTNCAYGARAARCAYAARTCNGARTTY YTNTCNTCNYTNATHACNAARYTNGGNATGAARAARCCNGTNATHGTNTCNCCNTCNATG AGYGGNACNTAYTCNYTNCCNTTYYTNTTYGGNGAYGGNGCNGARTCNYTNGAYYTNGCN ACNGGNTTYGTNCCNGTNGCNCCNATHCARACNAGYGCNTTYGTNAARAAYTAYATHAAY AGYCARYTNCCNACNYTNATHGTNTGYGGNAGYAARGAYGTNAAYATHGGNGCNATHAGY AAYAARGAYYTNGGNCAYYTNCCNAARGGNCARTAYGCNCCNATHAARGAYGCNGGNCAY GCNTGYTAYYTNGAYAAYCCNGAYGCNTTYCAYAARTAYYTNTAYCAYTTYYTNAAYCAR YTN--------------------------------------------------------- ------------------------------------------------------------ ---------------------------------YTNAARTAYGAYTTYGGNATHATHTCN AARTAYMGNACNTTYCAYMGNTTYTGGGCNGGNGCNYTNTGYCCNGTNYTNYTNTGYTAY CAYCCNACNGTNGTNAARACNGTNYTNAARTCNTCNGCNCCNAARCCNMGNGGNGGNTTY GTNAGYACNCCNTAYGAYATGGGNYTNMGNTGGYTNGGNGAYGGNYTNYTNYTNTCNAAY GGNACNAARTGGGCNMGNAAYMGNMGNYTNYTNACNCCNGCNTTYCAYTTYGAYATHYTN AARCCNTAYGTNTAYGTNTAYAAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHGAYYTNGTNAAYMGNGAYCCNAAYGAYYTNAAYGAYCAYGTNCAR GTNTGYTTYGARGAYGTNATHGGNGARCCNGARGGNGCNCAYTCNATHAAYTGYGTNTGG ACNAAYTCNTAYAARTGYTTYAAYTGYTGGAARAGYTGYTGYTAYAAYYTNATGACNATH YTNTGYGCNATHCCNATHTCNATGTGYTGGGGNTGYGARTTYGCNTAYATHACNTTYGCN CAYGTNTGGACNATHACNCCNTGYATGMGNACNTAYATGATHCARTGYGGNTGYATGCAR AARTTYTAYGGNACNTGYYTNCARTGYTGYATGCARCCNTGYTTYGARGCNATGGGNTTY NNNYTNAAYAAYATHAARNNNACNAANGTNAGY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNGAYACNACNMGNATHACNTCNTTYYTNTCN AARGCNAGYCAYGCNGAYATHTCNMGNYTNAGYCARTCNGTNGGNAGYCCNCAYAARGGN TTYAARGGNGCNGGNGCNGAYGCNCAYAAYGCNGTNCCNGAYACNAARGARYTNTGYMGN MGNYTNGARGAYAARATHAAYAGYYTNACNMGNATGGGNGGNAAYYTNCARAARGARAAY MGNGARATGGCNAGYYTNATHGAYMGNCARGGNGARAARYTNGAYACNGTNAARCARATH GARMGNAARGCNMGNGARACNMGN------------------------------TCNAAY TGGAAYCARGARACNAARGCNMGNYTNAAYGARAARATHACNTCNAAYGTNAAYGAYYTN GGNTCNYTNGCNMGNCARGTNATHMGNGGNTCNAARACNAAYGARTTYYTNGCNCARGCN GCNAARAAYTTYGCNTCNCARGARAGYTAYATHCARAAYTCN------------ACNGAR ACNATGAARAARATGGAYGTNATHMGNTCNCARYTNGARTTYCAR--------------- ---------------------------------CARTCNTCNATHTCNMGNAGYYTNCAR CAYYTNGAYGARGTNCARGAYCARYTNTCNACNYTN------CCNTCNGARAARGCNTTY MGNTGGTAYYTNGAYAAYATGAARAARGCNGGNGAYCAYYTNGTNYTNTTYCAYTGYACN GAYYTN---CCNCAYGGNATGYTNCCNGGNATGATGACNGAYGTNGARYTNGTNACNAAR CARTAYCARAARGTNMGNCARGARGCNGAYACNATHATHGCNAAYGCNACNGARYTNYTN CAYGARGARGAYGTNAARGCNTAYTCNGTNATHAARTTYAAYACNAARCCNCAYGARGCN GTNGTNCARGCNGCNTGGGARGARAARGTNGAYCAYATHGTNATGGGNACNMGNGAYYTN GGNACNATHAARMGNGCNATGGTNGGNAGYGTNAGYACNGARGTNGTNMGNGAYGCNCAY GTNCCNGTNACNATHGTNAARACNAARGARATGGAYAARYTNGCNYTNACNGGNAARGTN GCNATHATHACNGGNAGYAGYTCNGGNATGGGNCARGCNACNGCNATHYTNTTYGTNMGN MGNGGNGCNAARGTNACNYTNCAYGGNMGNAAYCARGCNMGNYTNGTNGCNGTNGCNGGN GARTGYAARAARGCNGGNGCNAARGAYGAYCARGTNYTNATHGTNGCNGGNGAYYTNATH AAYGARAAYAGYMGNCARGAYYTNGTNAAYAARACNGTNGARCAYTTYGGNAARYTNGAY ATHYTNGTNAAYAAYGCNGGNGCNYTNAGYGCNGARCCNYTNMGNGAYATHACNGARTCN GGNATHGAYCARATGATGGAYYTNATGTTYAARGCNCCNGTNTTYYTNACNAARGGNGCN YTNCCNCAYYTNAARAARACNAARGGNTGYATHGTNAAYYTNTCNACNGCNATHACNACN GARAAYYTNCCNGGNTTYTTYTCNTAYACNGTNGCNAARGCNGCNATHGAYAARTTYACN GARTAYGCNGCNYTNGARTTYMGNCCNTGYGGNATHMGNGTNAAYTCNGTNAARCCNGGN ATHACNGARACNGCNATHTTYGAYAAYGTNTTYGCNGGNGAYAARGAYCARGTNAARGGN TTYYTNGCNGTNCARACNAAYCAYTCNATGYTNGGNMGNAAYGGNCARTCNGARGARATH GCNGARATGGTNGCNTTYYTNGCNTCNGARGCNGCNAGYAAYGTNACNGCNCARCAYTTY YTNGTNGAYGGNGGNMGNAGYAARTAYTTYCAYCAYGGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------MGNAARAARAARGCNCCNAAYGARYTNYTNATGGARTTYGTNGAY TGYYTNATGAARAARGAYTTYCCNAAYGCNAGYAARYTNTGYAARATGATHYTNATGTTY GARCCNGARAAYGARGARGCNYTNAARTTYCARCCNYTNATHGARGARAARATGCARYTN GAYGCNGARGCNGCNGCNGCNGAR---------GARGARGARGGNAGYAGYGAYGARGAY GAYGAYGAYGAY------------MGNYTNTTYTGGGTNGAYYTNGARATGACNGGNYTN GAYGTNGARAAYGAYCARATHYTNGARATHGCNTGYYTNGTNACNGARAARGAYYTNGCN ATHGTNGCNGARGGNCCNAAYYTNGTNATHCAYCARAGYGAYGCNGAYYTNGAYGGNATG AARGARTGGTGYGTNGARCAYCAYGGNAARTCNGGNYTNACNCARGCNTGYMGNAAYTCN AARATHAGYGTNAARGARGCNGARAARATGGTNYTNGARTTYGTNCARCARCAYACNTCN AARGGNACNTGYYTNATHGCNGGNAAYTCNGTNGGNGTNGAYAARCARTTYATHACNMGN CAYATGCCNYTNYTNTCNGARCAYYTNCAYTAYMGNATHATHGAYGTNAGYACNGTNAAR GARYTNTGYMGNMGNTGGTAYCCNGAYGARTAYAAR------------------------ ---------GCNGCNCCNGCNAARAARACNTGYCAYMGNGCNYTNGAYGAYATHMGNGAR AGYATHGARGARYTNAARTTYTAYMGNGCNGCNATHTTYAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNCARCAYGAYCCNGTNGARAARYTNTGYAGYTCNTGGYTN GTNCCNACNCCNGARTCNCAYMGNGARCARGTNTTYTTYGTNGCNTTYYTNACNTGYGTN TAYYTNTGYYTNYTNYTNGGNTGYACNGCNACNGCNMGNGTNGGNTTYYTNGTNAAYMGN MGNATHAARCARGARATGMGNMGNACNACNMGNYTNTAYCAYGARGARGARGAYGTNCCN GAYATHMGNGARATGGCNATHATHGAYGAYYTNAARMGNYTNCAYAGYYTNGCNTGYYTN GCNGTNTGYGGNATHYTNACNTGGYTNCCNATHGCNATHATGYTNACNYTNCARAARTCN GGNGTNCARGTNAGYGARGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNGCNGTNAGYMGNCARATGTGYTAYACNTGYCARTTYGTNTCNAAYGGNCCNGGNYTN GARTGYGCNACNGCNCCNYTNAAYTGGACNGGNGGNGARGTNMGNATGAARTGYCCNACN ATGTGYACNACNATGGCNGARTTYGAYGCNACNACNGGNAARCCNACNTTYTTYCAYMGN GGNTGYGGNGTNGCNCCNGARGGNCARAARGAYGGNTGYACNGAYAAYGGNGCNMGNCAY AGYTGYTTYTAYTGGTGYGGNGAYGGNCARGAYTAYTGYAAYGAYAARTCNATHCCNMGN TCNCCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATHACNGTNAARTAY TTYGCNGTNTTYATHATHTTYYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYYTNTGYTCNGGNGCNYTNATHGTNAGY GTNGGNTTYGTNTCNTGYGARCAYMGNGARACNGCNGTNGTNYTNYTNGCNGTNGCNGTN GGNGTNGARGGNYTNTCNTTYGCNGGNTAYATGGTNAAYCAYGTNGAYTTYGCNCCNMGN TAYGCNGGNGTNYTNTAYGGNATHACNAAYATHATHGCNACNATHCCNGGNATHYTNGCN CCNATHGTNATHGGNGCNYTNACNCCNAAYAARTCNCARGARGARTGGMGNAAYGTNTTY TAYGTNTGYGGNGGNTTYTCNGTNATHGGNGCNATHGTNTTYGGNGGNTTYTCNAARGGN GARYTNGARCCNTGGGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GTNGAYTCNAARTGYGGNATHYTNGARCARGAYGGN GAYTAYAARAARTTYYTNGARGTNYTNGCNAAYCCNCCNGARCCNCCNACNATHTCNYTN GAYGCNATHGTNGARGARGTNGARGCNAARGARYTNMGNATGGCNAARATGAGYTCNTCN AARACNAGYACNCCNYTNYTNGARTAYYTNAARAARMGNAARGARGARMGNMGNATGAAY AGYYTNAARYTNMGNGAYGARMGNMGNMGNGGN---GGNMGNGAYMGNGAYAGYGAYMGN MGNMGNTCNGCNAARGAYGAYTCNGAYMGN------------------------------ ------MGNGAYMGNGAYMGNCARAARGAYAARGAYMGNMGNAARGAYMGNGGNAARGAR YTNGCNMGNGARAARGARMGNGARMGNMGNMGNGAYMGNGGNGGNGGNGGNGGNGGNMGN CAYAARGAYMGNMGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNAARTCNATHTCNGGNTCNTCNGARTCNGTNATGTCNMGNTTYGTNAGYGGNGGNYTN GAYCAYYTNNNNGTNCCNYTNGTNGARAARAARACNGGNGARACNATH---GGNYTNCCN CCNACNGCNGTNGGNAARTGYTTYAARATHMGNTAYGGNYTNGAYGTNTCNGTNAGYTTY AGYAAYAARCAYACNGARACNYTNAGYYTNACNATHCCNGGNATHYTNCCNMGNTGYAAY CARCARTGGGCNTCNTGGAARGCNCCNCAYTGGGCNTTYGARTGYCARACNMGNYTNTCN AAYTCNYTNTTYTCNGTNCCNGARCAYYTNYTNCAYACNGARGCNTTYTCNAAYYTNCCN GGNTTYCAYGTNYTNTGYGAYAARTGYCARATHAGYACNCCNCCNMGNTCNCAYCAYTGY AARGTNTGYCARGARTGYATHYTNAARMGNGAYCAYCAYTGYTTYTTYGCNGGNTAYTGY ATHGGNTAYTTYAAYCAYMGNTAYTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------GARCARATHMGNGGNGGNGGNGARATGTTYAARTTYCCNTGGACNTCNTAY TCNAARGTNCARCARTTYCCNGTNAARTTYTAYTGGAARCAYTCNMGNTTYTTYMGNTAY TTYTTYTAYTCNTCNGCNYTNATHTTYCCNYTNATGGTNAARYTNACNAARGCNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CARGCNGGNGCNGTNCCNAARATGMGNMGNACNYTNGARGGNGTNMGN GGNCAYCCNTAYACNMGNGTNTCNYTNTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------- >pinnata YTNATHYTNGCNCCNTTYYTNYTNGGNTTYGCNATGGCNGGNTAYGAYCCNTAYTCNGAY YTNGCNCARYTNTAYMGNTAYCARYTNYTNGCNAAYGCNTTYAGYGAYCCNGGNCARGAY ACNATGCCNYTNACNGAYGAYGCNAGYGAYATHGGNATHMGNTCNTAYTGGCCNGARYTN GCNGCNAGYYTNGARGARMGNGAYGCNAARCCNYTNGAYGAY---TCNGCNYTNTAYGAY TCNCARATHTAYAGYGGNGCNCAYATHMGNGAYCARGARCAYATHGARCAYAGYGCNYTN CAYGGNTAYCARTCNGTNGCNGGNGGNACNGCNGARGGNCCNGAYAAYAARATHCAR--- AARAGYGAYAARCCNYTNCCNGCNTAYTGYAAYCCNCCNAAYCCNTGYCCNATHGGNAAR ACNGCNAARGAYAAYTGYGTNGARGAYTTYGAYAAYAGYGCNGARAAYAAYAARAARYTN YTNAGYGARCARGAYTGYCCNTGYGAYACNGARCAYATGTTYAGYTGYCCNGCNGGNAAR GAYACNGTNTCNTCNAARGGNCARGCNGGNTAYCARCARACNYTNAAYAARGTNATHGAY CARYTNAGYAARATGGGNGCNGARGAYGAR------GARGGNGAYAGYYTNATGAGYCAR GCNAARMGNMGNATHTCNYTNGTNGCNAARAARTCNCCNCAYATHATHCAYAARMGNTCN GARAAYGCNGAR---GAYAAYCCNTAYYTNMGNGGNGCNMGNATGGARATHGCNGCNAAR AARAAYCAYGARATGGCNCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNAGY AGYGTNTGYTTYATHTTY---GGNGTNYTNCARYTNTCNTCNGGNGCNAGYYTNGARAAY AARTAYGARCCNATGGTNGCNTTYATHTGYGAYMGNCCNGCNATGCAYMGNGGNATHAAY GGNTGGGTNGCNGAYAARACNCARGAYTGYCCNGAYACNYTNGAYGAYGTNYTNGCNTAY TGYAARAARATHTAYCCNGAYCAYAAYATHACNAAYGTNGTNGARTCNTCNAGYTTYTAY GAYATHGARAAYTGGCCNATGGGNAARGCNGGNMGNMGNCAYACNCAYCAYGTNMGNCCN TTYMGNTGYYTNGTNGGNGGNTTYCARTCNGAYGCNYTNYTNGTNCCNCARCAYTGYGAR TTYGAYCAYMGNGCNGAYATHTCNCARTGYAARGARTTYTCNCAYTGGAAYACNGTNGCN GAYGAYGARTGYYTNAARAARGGNATGCAYYTNGARTCNTTYGGNATGYTNYTNTAYTGY AAY---YTNGGNCAYTTYAAYGGNGTNGARTAYGTNTGYTGYCCNAAYCCNTCNAAYACN MGNGTNCAY------CCNGARCCNAARGGNGAYGAYAARCCNGAYGAYTGGGARAGYGAR GARAARGAYGARGAYGAYGAYAGYGARGARAARAGYACNGAR------------------ ------TCNGCNAARTCNTCNGARAGYGTNGAY--------------------------- ---------------------------GAYGARAAYAGYCCNGAYGTNTAYGARGCNTAY YTNMGNGGNYTNACNYTNCCNTCNGTNTAYACNAAYGARCAYGARCARTAYYTNGCNGCN AARGCNMGNATGYTNGTNGTNCARAARAARAARGARGCNAARYTNYTNGAYGARTTYGAR AARACNCARGARAAYGTNGAYAARGTNMGNAARACNGAYCCNAARGCNGCNAAYAARATG AAYGARGARATHGCNGAYMGNTTYAARCAYYTNTAYGCNTCNTTYAARCARGARGAYGCN GCNGARAARYTNCARYTNGCNGCNYTNCAYCARMGNMGNGTNCARGCNGCNYTNAAYGAR MGNAARMGNGARGCNATGGAYAARTTYATGCARGCNYTNGARGAYCARAAYATHGCNAAR GTNTCNAARTAYYTNCAYAAYTAYATHAARGTNGARGARAARGAYMGNACNCAYACNGTN AAYCAYTTYGARCAYYTNAARYTNTCNGAYGCNAARGARGCNYTNMGNGTNCAYCCNCAY ATHATHMGNCAYYTNAARYTNTCNGARATGMGNATHGAYCARGCNYTNGARATGATGACN CAYTAYCCNAAYGTNGARAARGCNGTNMGNCCNGARATHGARGARTTYATGAARGGNTTY AAYAAYATHGCNGAYMGNATHAARAARGTNGTNGTNCCNGTNCCNGARGTNAARGAR--- ------------ACNAGYAGYTAYGAYTTYGARGARAGYACNAGYAAYACNAAYAGYAAY GAYAAYGARTAYCAYTTYGAYTCNAGYAGYGARGARCARAAYAGYAGYGAYAAYTCNGCN ATGGTN---------------------------------------GAY------------ ---------------------------GAYGARGTNCARGARAAYGARCAYAGYTAYGAR ---GGNCAYCAYTTYGCNGCNAAYGCNATGGCNGAYACNCAYAGYGCNCARCAYAGYGTN ATHMGNTCNAGYGCNTCNTCNAGYAGYYTNGGNAGYACNATHGGNATHGTNYTNGGNGCN ATHAGYGTNATGGTNATHGTNGTNGTNGCNGTNGTNATGGTNMGNCAYAAYAARCAYMGN CARCCNGTNTCNAGYGGNTAYGTNGARGTNGAYCCNTCNGCNTCNCCNGARGAYMGNTAY YTNGCNAAYATGCARATGAAYGGNTAYGARAAYCCNACNTAYAARTAYTTYGAR------ ---AARGAYAARYTNTAYMGNCARGTNACNGTNGARGTNAARGGNCAYGAYCCNTCNGTN ATHAAYAGYTAYCARAARTTYACNACNATGGCNGCNGARCARYTNGGNATHACNATHGGN AGYATHTCNGARCCNCCNMGNGTNATHACNMGNAARAGYYTNYTNAARTCNGTNTTYATH TTYAARAARCAYCARCAYCARTAYGARCARMGNACNYTNTTYMGNGTNTTYGARTTYAAR CAYYTNACNGARTCNACNGCNYTNACNTTYYTNGARTAYATHCARMGNAAYYTNCCNGAR GGNATGGCNATGAARGTNACNAARCAYGARYTNCAYCCNATGCCNGARCAYYTNAARCCN CCNGARYTNTCNMGNYTNGARGCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CCNGAYTCNGGNGARAARATHACNYTNGGNATHACNGTNYTNYTNGCNTTY TCNGTNTTYATGYTNYTNATHGCNGARAGYATGCCNGCNACNTCNGAYTTYGTNCCNYTN ATHGGNATHTAYYTNACNGTNACNATGGGNATGACNTCNYTNTCNATHATHYTNACNGTN YTNGTNYTNCARYTNCAYCAYGTNGGNCCNCAYCARAARCCNGTNCCNMGNTGGYTNTGG TCNYTNGTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CARMGNTGGATHCCNYTNGAR TCNAAYCCNACNGTNYTNAAYAARTAYGTNCAYGGNYTNGGNATGGAYAARGGNTGGAAY TTYGTNGAYGTNTTYGGNYTNGAYCCNGARYTNYTNGCNATGGTNCCNMGNCCNGTNGCN GCNATHGTNYTNYTNTTYCCNAGYAAYGAYAGY------------GGNGARGARAGYGGN GARYTNATHAARGAYATHCCNGAYGAYYTNTAYTAYACNAARCARACNATHGAYAAYGCN TGYGGNACNGTNGCNATHGTNCAYGCNYTNGCNAAYAAYGTNTCNMGNATHAAYTTYGAY GCNGGNAARCAYTTYTGYAGYTTYYTNTCNGCNACNAARTCNYTNAGYCCNGARGAYAAR GCNAARMGNYTNGARGTNGAYYTNCARATGGGNTCNGCNCAYGARGTNAGYGCNCARGAR GGNGAYACNGCNGCNCCNGAYGCNACNGARMGNGTNAARTGYCAYTTYATHTCNYTNGTN CAYTTYAAYGGNAGYYTNATHGARYTNGAYGGNMGNAARGARGGNCCNGTNAAYCAYGGN CCNACNAARGARGAYTCNTTYYTNGARGAYGCNGCNYTNATHGTNAARAARTTYATHGAR MGNTGYCCNTAYATGGCNGCNMGNAARYTNYTNYTNMGNMGNGAYCARAGYACNGGNYTN GGNTAYAGYYTNGTNYTNACNAARGAYGARGARATHGTNTCNAAYGCNATGTTYAARGAR AARGCNGCNATGATHGARAARAGYMGNYTNGGNMGNGARACNTAYTTYCCNGCNYTNAGY TAYTTYAARTCNAARCCNYTNATGGARAARACNAAYGTNTAYMGNYTNATHAARGCNATG CCNAARGGNGGNGTNYTNCAYYTNCAYGAYATGGCNATGACNAGYYTNGAYTGGYTNGTN AGYAAYGTNACNTAYMGNGAYAAYYTNTAYTTYTGYGTNAARAGYAAYACNTCNYTNCCN YTNTTYCAYTTYTTYMGNACNCCNCCNAAYCCNGGNTGYATHTGGAARYTNGTNAARGAR GARMGNMGNATGGCNGARAAYGTNGAYGAYTTYGAYGCNAGYYTNMGNAARAGYATHAGY YTNYTNACNACNGAYCCNTTYGTNAGYTAYCCNTCNYTNACNGARGTNTGGGAYMGNTTY GCNTCNTAYTTYGGNCARGTNTTYGGNYTNATHTTYTAYAARCCNGTNTTYCARGAYTAY TTYMGNMGNGGNYTNGARGARTTYATGGARGAYAAYGTNCARTAYATHGARYTNMGNGTN YTNATGGGNGGNGTNTAYGAYYTNGAYGGNAARACNGGNGAYACNCARGGNACNTTYGAR YTNTAYMGNAGYGARYTNGCNMGNTTYATGMGNGCNCAYCCNCARTTYATHGGNGCNAAR TTYATHYTNACNAGYGAYMGNTCNCARAGYCARAARGTNATHATGGARGGNATHAAYAAY GCNATHAARATHMGNCARAARTAYCCNGAYYTNATGYTNGGNTAYGAYYTNGTNGCNCAR GARGAYCCNAAYCAYACNYTNYTNTTYTAYAGYAARCARYTNYTNTCNCCNAGYCARGGN AAYCCNCCNGTNGAYYTNCCNTTYTTYTTYCAYGCNGCNGARACNAAYTGGCARGGNACN GGNACNGAYTAYAAYYTNATHGAYGCNATHYTNYTNAAYACNACNMGNATHGGNCAYGGN TAYGGNYTNGCNAARCAYCCNACNYTNGCNAARGARGTNAARGAYMGNGGNATHGCNGTN GARGTNAAYCCNATHTCNAAYCARYTNYTNGGNYTNTTYAARGAYCCNMGNAAYCAYGGN YTNGTNCCNYTNATGGCNGAYGAYTTYCCNATHGTNGTNAGYTCNGAYGAYCCNGTNGTN TGGGARGCNGCNCCNYTNTCNAGYGAYTTYTAYGTNGCNTTYATGACNATGTGYGGNGAR GAYTGYGAYYTNMGNTTYYTNAARCAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGGNATGYTNMGN YTNGGNAARAARAAYTCNGTNAGYGGNGARMGNYTNGAYAARAAR--------------- ---------------------------------AAYYTNCARATGYTNMGNYTNGGNAAR AAR---ATGGAYCCNGAYGTNYTNAARMGNAARATGATHGGNYTNYTNMGNYTNMGNAAR MGNMGNATGGGNATGYTNMGNYTNGGNAARMGNGGNATGAAYACNYTNMGNYTNGGNMGN MGNAGYYTNGGNGCNATHMGNYTNGGNMGNMGNAAYYTNTCNATGYTNMGNYTNGGNAAR MGNAGYATGAAYGTNYTNMGNYTNGGNAARMGNCAR------------MGNCARGGNGAY GAYGTNGAYGGNGCNGGNGCNGTNGGNAARMGNMGNATGAAYATGYTNMGNYTNGGNMGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CCNATHGARTGYTTY TCNGARGAYGTNCCNYTNAGYCCNGCNAARMGNGARTAYGCNMGNAGYTAYTGYTGGYTN CAYAAYACNTAYMGNGTNCCNGAYAGYGTNGARYTNCCNGTNGGNCARAGYGAYMGNTCN CARTCNGARATHCARTAYTAYCARTGGGTNCCNATHATHYTNYTNGTNATGGCNATHYTN TTYAARYTNCCNAAYYTNATHTGGMGNYTNACNAGYTAYAGYTGYGGNYTNGAYYTNACN AARATHGCNACNYTNGTNTCNAARTCNCARATGATGACNCCNGARCARTCNAARGAYACN YTNYTNCARATGACNAAYTAYYTNGAYMGNTGGYTNAGYTCNAAYCAYYTNYTNGTNACN AAYCAYGGNTCNACNGCNTAYMGNTAYTGGGCNACNTAYATHMGNTGYTGGGGNAARGGN AAYGGNACNTAYYTNACNGGNYTNTAYYTNYTNACNAARTTYYTNTTYYTNTCNACNTCN GTNTCNATHTTYTTYYTNYTNTGGCAYGTNYTNGGNAARTGGTAYYTNGGNTTYGGNYTN GAYATGGTNAGYGARGAYAGYGARMGNGCNGCNYTNCARCARYTNCCNTAYTTYCCNAAR YTNACNTTYTGYGAYTTYAGYGTNMGNCARCARAAYAAYATHAAYACNCAYACNYTNCAR TGYGCNYTNCCNATHAAYATGTTYAAYGARAARATHTTYTCNTTYYTNTGGTTYTGGATH ATHATHGTNACNGCNATHAAYGGNGTNAAYTTYATGATGTGGYTNTAYAARTTYCARTTY GGNACNYTNMGNGGNAGYGGNGTNTGYCARYTNYTNAAYCAYGGNGAYYTNATHACNGAY TAYGAYMGNATHYTNGCNGCNAARTTYGGNCAYAARTAYYTNGGNMGNGAYGGNTGYTTY GTNATGGARGTNGTNCARAARAAYTCNAAYGTNTTYGTNACNGGNGAYYTNGTNAGYCAR YTNTTYMGNYTNTAYMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATHCCNACNMGNACNGCNGARGAYACNYTNCARGAYACNTCNTCNYTNGTN YTNGAYAARMGNCCNAARTAYATGGAYACNMGNMGNGAYYTNGAYGTNTTYAARGAYYTN GTNYTNATHAGYYTNCARGARYTNGTNGAYGARGGNMGNYTNGARTCNTCNATHYTNCCN GARGAR------GAYMGNCARACNAGYAARCCNGTNGARAARMGNMGNTAYATGGGNYTN TGYATGCAYMGNCARGCNAAYCARTAYATHCCNTTYCCNTGYGTNMGNACNGGNMGNATG AARACNGARYTNTGYATHYTNYTNGTNATHTGYGCNGTNGCNTTYGCNGAYAAYTAYYTN TGY---CCNAARAGYGGNGARACNTTYGAYTGYTTYGARTCNTCNAARGAYCAYMGNACN TGYYTNACNAAYTCNMGNCAYTCNGARAGYTAYGTNGTNTGYGGNAARTGYACNMGNAAR TGGGARTAYTGYGTNACNAARGGNGARTTYGTNAARTCNAARCARCCNGARMGNGAYTGY GGNGCNGAYTAYGARTCNACNCCNTGYACNGCNCARAAYTCNCAYTGGTCNAGYACNTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ACNYTNATHATH ATHTCNTCNTAYACNGCNAAYYTNGCNGCNTTYYTNACNATHGARAARYTNGTNGCNCCN ATHAAYTCNGCNGAYGAYYTNGTNAAYCAYCCNACNATHAARTAYGGNACNAARTCNACN GGNACNTCNTGGMGNTAYTTYGARCAYTCNACNATHGAYACNTTYATHGCNATGAARAAR TTYATGGTNGARAAYGCNGAYGARGTNYTNTTYACNAAYTAYGAYGAYGGNGTNMGNAAR GTNMGNGARTCNAARGGNGARTAYGCNTTYYTNYTNGARTCNGCNATGAAYTCNTAYCAY GCNCARCARGARCCNTGYGAYACNATGATGGTNGGNGAYCCNYTNGAYAAYAARGGNTAY GGNGTNGCNACNTAYATHAAYTAYCCNYTNMGNCAYAAYATHAAYATHGCNGTNYTNACN YTNGARGARAARGGNGARYTNATHAARYTNCARCARAARTGGTGGYTNGAYAARGGNCAR TGYGGNGCNCARAAYTCNGGNAARGARTCNACNGGNTCNCARAGYGCNYTNACNYTNAGY AAYGTNTCNGGNATHTTY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNACNTTYYTNAAYATHAAYGARGCNAAYCCNACNAAR AAYGARGTNGARATHGAYGCNTGGYTNTCNCARAARTGGACNAAYAAYYTNATHTTYAAY MGNAGYMGNTTYCAYAAYATHTCNTCNGTNAAYGTNCARGCNGAYGARGTNTGGACNCCN GAYATHGCNGTNTAYCARGGN---GAYATGMGNATHACNGAYGARMGNTCNAARATHGTN ATHTTYAGYGAYGAYGGNTTYTCNYTNTAYGTNCCNCCNGTNMGNATHMGNACNCAYTGY GAR---------GTNGTNGARCAYGGNAAYACNACNTGYCARATGAARTTYGGNTCNTGG ACNTAYAAYGGNYTNMGNYTNACNYTNGGNGARGAYGTN---TCNGTNCAYYTNAAYAGY TAYTCNGCNGCNTCNAARTTYGARGTNGTNGARACNACNGCNAARMGNAAYYTNGTNMGN TAYAARTGYTGYCCNGARCCNTAYGARGAYATHGARATHACNTTYACNTTYACNAARAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GAYGGNGARGAY GCNTTYGAYAGYTTYTTYAAYGAYGAYGARATHGARGARAGYTCNGGNAARMGNTTYGAY ACNGGNGCNCCNMGNTTYGTNGGNAARMGNCARGCNCCNMGNTTYGTNGGNAARMGNGAR CCNCCNMGNTTYGTNGGNAARMGNGGNGCNCCNMGNTTYGTNGGNAARMGNGARCCNCCN MGNTTYGTNGGNAARMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYGTNMGNYTNCCNACNTCNYTNGTNCCNGTN CAYTAYGCNGTNMGNYTNCARGARGAYCCNAARAARTTYACNTTYAARGGNTAYGTNAGY ATHAARGTNAARTGYYTNGARCCNACNGAYAAYATHACNYTNCAYTCNGTNATHYTNACN ATHGAYGTNGCNTCNGTNCARTTYAARTCNAGYCCNTCNTCNAAYGAYCCNACNGTNTCN ACNTTYCAYGAYAARGARMGNGARTTYTTYATHGTNGARAARGAYAARGARTAYGARATH TCNATGAAYTAYACN------------------TCNCCNYTNCARCCNACNYTNAARGGN YTNTAYYTNAGYTCNTAYACNGARACNAAYAARACNATHTAYYTNGCNACNACNCARTTY CARCCNACNGAYGCNMGNMGNGCNTTYCCNTGYTTYGAYGARCCNGCNATHAARGCNACN TTYGAYATHACNYTNGTNMGNAARCARGAYYTNATHTCNATHTCNAAYACNCCNATHTCN AGYAGYCCNTGGGTNGARGAYGGNATHACNGCNGAYAARTAYGTNACNACNCCNAARATG TCNACNTAYYTNYTNGCNTTYGTNATHTGYGAYTTYACNTAYAGYTCNGGNGTNGCNTCN AAYGGNATHACNTAYMGNGCNTTYTCNMGNCCNGAYGTNGTNAAYTCNACNAARTAYGCN YTNTAYGTNGGNYTNGARYTNYTNCCNTTYTTYGARACNTAYTTYAAYTCNACNTAYCCN YTNCCNAARCARGAYATGATHGCNATHCCNGAYTTYGCNGCNGGNGCNATGGARAAYTGG GGNYTNATHACNTAYMGNGARACNMGNATGYTNTTYTCNGARGGNATHTCNAAYAGYGCN AAYAARGARGGNGTNGCNATHGTNGTNTCNCAYGARYTNGCNCAYCARTGGTTYGGNGAY YTNGTNACNCCNTCNTGGTGGGAYGAYYTNTGGYTNAAYGARGGNTTYGCNACNTTYATG CARTAYYTNGGNGTNGAYTTYGTNCAYCCNGAYTGGMGNATGTTYGAYMGNTTYGTNYTN GAYGAYACNCAYMGNGTNYTNTTYTCNGAYGGNYTNGTNACNTCNCAYCCNGTNTAYGTN CCNGTNTAYAAYCCNGAYGARATHAAYGARATHTTYGAYGAYATHTCNTAYTCNAARGGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARAARAGYGGNGGNAAR YTNGTNTAYGAYMGNGCNTAYYTNATGGARYTNMGNGARTGYGTNTCNTCNCARACNAAR CCNGAYGGNYTNCCNGCNYTNGARATHATHYTNGAYCARCCNACNCCNTTYYTNAGYMGN CCNTCN---GGNGGNCCNGCNGAYTTYACNCCNTCNTTYTTYCARTCNGGN---GGNAAY CARMGNCAYGCNCCNCCNATHGGNAARAGYAGYAGYMGNGGNMGNCARMGNCCNGGNGAY ATGCCNGGNACNCCNMGNGTNATHAARAGYATHTCNATHTCNACNGAYGTNAARCCNYTN CAYCARAGYGARAAYCCNTGGAAR---------CCNGCNAARAARGARGAYAARAGYGAR CCNAARACNYTNGARGGNGARATHYTNTTYATHATGAAYMGNYTNACNCCNACNAAYTTY GARAARYTNGCNACNGARATGAARMGNYTNAAYGTNAARACNTAYAGYGAYYTNCARCAR ATGGTNAAYATHTTYTTYGAYAARGTNACNYTNGARACNAARTTYGTNGARGCNTAYGCN CARYTNTGYAARGTNATGTCNCARYTNAARGTNCCNCCNCCNTCNGAYGGNACNGTNAAR GARAAYATGGCNACNTTYMGNGTNGTNATGYTNACNAARTGYCARCAYGARTTYGARGCN GAYAARTCNGTNGTNTTYGARGCNCCNGARGARAARAARAARAARATGGARGCNGARAAY CCNGARAARACNCCNGARMGNGAYGARYTNATHCARAARACNYTNTAYCAYATGAARYTN MGNMGNATGAARTTYTAYGGNAAYATHMGNTTYATHGGNGARYTNTTYAARYTNGGNATG YTNACNGARAAYATHATGCAYGAYTGYATHTTYMGNYTNYTNAARGCNMGNGAYGAYGAY TCNYTNGTNTCNYTNTGYAAYYTNYTNACNACNGTNGGNMGNYTNYTNGAYTCNGAYAAR GCNMGNCCNMGNATGGAYCARTAYTTYYTNCARATGTCNAARATHGCNGAYGARMGNAAR TCNMGNATHAARTTYACNYTNMGNGAYGTNATHGAYYTNMGNYTNAAYCAYTGGGTNCCN MGNAARGARGCNGCNGGNCCNAARAARATHGAYGARGTNCAYAARGAYTAYGCNCARGAR CARGCNMGNAAYCARTAYYTNGCNTCNCARCCNCCNCCNCCNMGNAAYGAYAAYGCNCAR GTNGGNAGYMGNMGNGGNAGYMGNCARMGNCCNGAYGARAAYMGNATGAGYGARGAYGGN TGGAAYACNGTNCCNAAY---AARAAYYTNMGNATGATHGAYGCNAAYAARATGAARATH TCNAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNACNGAYAAYTGGATGGAY GARYTNGARGAYYTNTCNGAYCCNYTNGGNGAYGAYAGYATGGARACNTTYGTNAAYYTN GAYCARTTYYTNAAYGGNAAYTCNTTYTTYGAY---------GAYGAYAAYYTNGCNYTN GAYGAYGTNGCNTCNGARGTNACNCCNGTNATHGAYYTNGGNGGNGAYACNACNTTYAAY MGNGGNAAYYTNACNACNCCNGARGCNAAYATHCAYGARCARATHGARTCNAARTCNCAR AAYTCNTCNTTYAARCARCCNGCNCARAARGGNATHGTN---------ACNAGYYTNTAY GARATHCCNGTNTCN---------------ATHGARGCNGCNGCNGTNGTNCAYACNTCN ACNATHTCNGAYACNGARYTNGAYCAYGAYTAYAGYTCNAARMGNCARMGNATGTCNATH CCNTCNGARGTNAAYGAYAARCCNTCNACNAGYAAY------TCNGARYTNACNAARMGN TTYTCNMGNCCNTCNAAYATHTAYYTNAARGCNGCNATHCCNACNACNGTNTCNACNCCN TCNGAYAAYATGTTYYTNGAYAAYAAYATGGAYAARCARACNATHMGNMGNATHAARAAY AAYTAYGCNTCNAARMGNTCNMGNGARCARMGNAARCARAARYTNAGYGARATGGAYGTN GARGCNGARGARYTNGARGTNMGNAAYCARAARYTNMGNCARAARATHATHGARYTNGAR AARYTNGCNAARGTNATGAARGCNGCNYTNGTNGCNAARATGGCNGGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CCNCCNCCNCARGGN CARYTNGCNGCNGCNGCNTCNGGNACNAAYACNCCNTAYAAYAARGAYATHGTNCCNGAY ATHAAYAARAAYAAYMGNYTNAARGAYACNTCNGGNGTNACNAGYAGYTCNCARTCNTTY GTNTTYGGNAGYAAYYTNTCNCARMGNGTNACNGGNATHACNTCN---TCNCCNGCNGAR YTNGARGCNGCNTCNTCNTCNGGNTTYGTNTTYGGNGARTCNYTNGCNTCNMGNGCNGTN GTNGARACNAAYGGNTCNATHCARCAYAARGAR---GAYGARAGYGAYTCNGAYTCNGGN AAYAARYTNAAYCARACNYTNGARGARTCNGCNAARGARTAYCARGCNAARCAYGAYAAY AARACNGARYTNCARGTNGTNGARACNGTNACNGGNGARGARGARGARTCNAAYGTNYTN CARGCNAAYGCNAARYTNTTYTTYTTYGARACNAGYAAYGARTCNTGGATHGARMGNGGN MGNGGNACNATHMGNYTNAAYGAYATGTCNGCNAARGAYAAYACNAAYTTYCARTCNMGN YTNGTNATGMGNACNCARGGNAGYYTNMGNGTNGTNYTNAAYACNAARATHTGGCCNGGN ATGTCNYTNGARMGNGCNTCNCCNAARTCNGTNMGNATHACNGCNATGGAYACNGAYGAR ACNATHMGNATHTTYYTNATHACNACNAAYGTNAARGAYTCNGARAAYYTNYTNMGNGCN ATHGAYTGGMGNATHCARCARYTNAARATHCARGARGARCCNGTNMGNCARTCNTCNGAY ACNMGNATHGGNGAYAARMGNAARGCNGAYGAYTCNGAYTTYGARCAYCCNCAYAARAGY AARAARAGYAAYAGYTCNCCNGAYACNGGNATHTCNATHAGYAARAARGARGARTCNGAY AGYAGYGTNCARGAYCCNGARACNGARGCNTCNTGYGARAGYCAYTCNTCNTCNYTNACN ATHAARTCNGARTCNGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNGGNGARMGNGGNAARACNGARTAYATGGGNTAYYTNYTNYTNTCNTGY CARYTNGTNCCNAARTCNGARGARGAYAARGAYCAYTTYTTYAARMGNTCNGTNMGNTCN ACNGAYTCNGCNAARAARYTNAARATGCARTCNTGGACNGGNGTNGTNAAYATHGTNYTN ATHGARGGNAGYGAYYTNGTNCCNATGGAYGAYAAYGGNYTNAGYGAYCCNTAYGTNAAR TTYMGNYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATGCARTAYTGYMGNGGNTCNGTNATHAAYGCNATGAAYGAYMGNYTNAGYACNGGN TTYTCNGARCARGARATHYTNMGNATHTTYTGYGAYATHTGYGARGCNGTNTCNMGNYTN CAYCAYTGYCARACNCCNATHATHCAYMGNGAYYTNAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGCNTCNAAY ---GTNTCNMGNACNATHGCNAARTCNYTNAARGGNMGNACNTTYGCNACNGCNGCNGCN GCNCARGCNGARAARGGNAAYGTNGCNAAY------------TGYTCNATHAARAARYTN AAYAAYGGNATGCAYGTNGGNGTNATHAAYTCNAAYTCNCCNGTNTCNMGNGTNGCNGTN GTNGCNCAYGCNGGNTCNMGNTTYGARGAYGGNGARAAYCARGGNATHACNCAYTTYYTN MGNATGTCNACNMGNYTNMGNTCNMGNAAYATGACNAGYYTNAGYMGNACNMGNACNGTN CARCARATHGGNGGNGAYGTNACNATHATGGGNACNMGNGARTAYATHTAYTAYAARAGY GCNGTNACNMGNAAYTGYYTNAAYGAYATHGTNGCNGTNYTNCARGAYYTNACNACNAAR CAYGCNTAYGGNCCNTGGGARYTNGCNAAYGTNCARAARGAYCARAAYGGNATGGCNYTN GAYYTNGCNYTNYTNGARAAYMGNCCNCAYGTNMGNGCNYTNGARYTNYTNCAYTCNGCN GCNTTYMGNAAYACNYTNGGNAAYTCNYTNTAYGCNCCNGARCAYAARATHGGNAGYTAY ACNGCNAAYCARATHYTNCARTAYGTNAARACNTAYTTYAGYGTNGGNMGNYTNGCNYTN GTNGGNATHGGNGTNGAYCARGTNCAYYTNGARGARYTNGCNTCNTCNTTYGARCCNTTY GCNTCNGTNGGNGTNCCNGARGARAARGCNGTNTAYAAYGGNGGNGGNGARATHMGNGAR AAYTGYGGNGGNGAYYTNGCNCAYGTNGCNGTNGGNGTNCARGGNGCNAGYYTNACNAGY AARGARYTNYTNGCNGTNGARGTNYTNMGNCAYATHYTNGGNTCNGGNCCNCAYATHAAR TAYAGYAGYGGNTCNTCNGGNGCNYTNYTNGCNAARGGNGTNGCNGGNGCNACNAAYGCN CCNTTYCAYGTNTCNGCNYTNAAYGTNAAYTAYACNGAYCARGGNYTNTTYGGNTTYTCN GCNGTNGCNCAYTCNTCNAAYATHGARAARGTNGTNYTNGCNGCNGCNAAYCARTTYAAR AGY---YTNGCNGCNAGYGTNTCNGAYAARGAYATHGCNMGNGGNAARAAYCARYTNAAR GCNGARATHTGYATGCAYTTYGARAAYCCNGAYGTNYTNYTNAAYTGGYTNGGNGARCAR GCNTTYGGNGGNAAYGCNGTNGTNACNCCNGARGAYATHTAYAARATGGTNGAYGGNATH AAYGCNAAYGAYGTNAARAAYGTNGCNAAYAAYGCNYTNAARTCNMGNCCNTGYATGTCN GCNGTNGGNAAYACNAGYAAYGTNCCNTAYYTNGAYAARYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNACNGAR CARAGYTCNYTNTCNYTNAAYGAR---GARAGYGCNCCNGCNACNCCNTCNGAYACNGCN GARACNGGNGCNGCNGAR---------GGNAARTCNGCNGARACNGGNGARGTNGCNGCN CCNAGYGARGARTCNGCNCCNGCNACNGTNMGNACNGARATHACNTGGGARAAYGGNGGN GARAAYGTNYTNGTNAGYGGNACNTTYAAYAGYTGGAARGARAAYGTNGCNYTNTCNAAR GARGGNGARATHTTYAARGGNTTYGTNGAYYTNCCNGTNGGNGARTAYYTNTGYAARTTY ATGGTNGAYGARCARTGGGTNGTNAAYAARAAYYTNCCNATHAARTCNGGNGARGAYGGN CARGARAAYAAYGTNATHYTNGTNTTYTTYYTNAARAAYYTNCAYTAYTTYGTNTGYTTY ATHGTNTGYACNTTYTGYYTNACNGCNTTYGGNAAYTTYATHCARTTYCCNTCNMGNTTY AAYCCNAAYGARAAYATHGAYACNCCNAGYGTNATHTCNAGYTTYATHTGGGAYYTNTTY YTNATHTGYYTNTTYATHGGNCARCAYTCNYTNATGGCNACNTCNTGGTTYAARAARCAR YTNCARGCNTGYTTYAARATHTCNGTNTCNGARMGNYTNYTNTAYYTNAGYGCNACNAGY TTYTTYYTNATGTTYYTNATHYTNAAYTGGCARCARATHCCNCARGTNTTYYTNTGGGAY GTNGAYGTNGARAARMGNTGGTAYYTNTGGACNTTYTTYGGNYTNYTNCAYATHYTNTGY TGGGTNATGATGGGNYTNGARATGGTNYTNYTNNNNTGYCARGARTTYYTNGGNATHACN CARGTNCAYAAYTAYCAYAAYGGNYTNGCNCARCCN---YTNACNAARAARAGYGARGGN GTNMGNGARATHTTYTCNMGNATGMGNCAYCCNGGNCCNGTNYTNYTNTCNGTNYTNYTN TGGYTNCARYTNTCNATGACNYTNGAYMGNYTNYTNYTNGCNTCNGTNTTYACNGCNTAY ATGGTNATGMGNAARGARTTYGAYTAYCARCAYTGYCARTGGGCNMGNAARCAYTAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGGGARACN AARCARGTNTTYGARTGGGCNAAYGCNGTNGGNYTNAGYGAYCARACNGAYYTNTTYYTN GAYAAYAARGTNGAYGGNATHCAYYTNYTNACNACNGAYGCNYTNCARYTNGARMGNATG GGNATHAARACNGCNCARGARGCNYTNMGNATHGARAAYMGNATHMGNGARYTNAAYTAY GCNAARMGNCARTGYGTNGGNAAYATHGARACNYTNCCNTAYCARTAYTAYCARGCNYTN AAYYTNGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNCCNACNTTYYTNTAYTGYATHGTNGTNCCNGCNGTN YTNYTNGTNGTNTTYATHTTYGTNYTNTCNATHTTYATGTGYTGYTAY---MGNGCNTGY AARTGYAARAARTAYTCNTCNYTNTCNACNGARACNAAYGAYATHCAYYTNGARGAYTAY AAYACNATHMGNMGNGCNTCNATHAGYYTNMGNCARATGTCNCAYAAYMGNGAYACNCCN ATHATGGGNAGYMGNACNGGN---TCNATGACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TAYGARAARTAYYTNGGNTTY YTNYTNGARYTNYTNAARATGGAYGTNAAYATHGTNATHTTYATHGARCCNAARGGNGTN AAYTTYGTNAARMGNATHMGNMGNAAYMGNGARAARMGNACNMGNATHGTNCCNATGAAY ATHTCNGAYYTNCARTAYTTYTCNATGYTNCCNMGNATGACNGARATHATGGARAGYAAR GARTTYCARGARAAYAAYAGYAAYTAYYTNAGYGGNYTNGCNGARGGNACNTAYCCNYTN TAYAAYYTNATHGTNAAYTCNAARYTNGGNTTYGTNCAYCARGCNATHCARCARAAYATH TTYAARTCNGARTAYTTYGTNTGGYTNGAYAGYGGNTAYGGNCAYGGNGAYTCNAGYATH TAYCCNCCNGAYGGNATHTGGAAYCCNMGNCAYYTNTTYCARTAYCCNGAYAARGTNACN TTYGCNGCNTTYGARAAYYTNACNAARATGAGYYTNGAYGCNAARAAYYTNCAYAARATH GARACNGCNTGGATGGCNGGNGGNYTNYTNGCNGGNAGYYTNACNGCNATGGAYAARTTY TAYTTYYTNCAYAARTCNGTNYTNATHGARAAYYTNGARMGNGGNMGNATHGAYGAYGAY CARACNATHAAYGTNGAYTGYTTYYTNAAYGAYCCNGGNAAYTTYAAYCCNGTNYTNGGN GGNTGGTAYGAYYTNATGAARCCNYTNYTNMGNACNGTNCAYAGYGTNATHCAYACNACN CCNCCNAARYTNYTNAARGARGTNGTNYTNATHGAYGAYGGNAGYGAYTAYGAYTTYYTN CARGARAARYTNGARAAYTAYATHAARCARTTYAAYGGNYTNGTNAARYTNTAYMGNAAY CCNGARMGNTAYGGNYTNATHACNGCNMGNACNAARGGNGCNGARCAYTCNACNGGNGAY GCNATHGTNTTYYTNGAYGCNCAYTGYGARTGYAAYAARAAYTGGYTNCCNCCNYTNYTN ACNMGNATHAARTAYGAYMGNACNATHYTNGCNGTNCCNATHGTNGAYGGNATHAAYTGG GAYAAYATGGCNTAYTAYACNACNTAYGAYCAYAAYYTNCAYMGNGGNATHTTYGARTGG GGNTTYYTNTAYAARGARGGNYTNGTNCCNGARAARATHYTNAARGCNMGNGARCAYCCN AGYGARCCNTAYGCNTCNCCNACNCAYGCNGGNGGNYTNYTNGCNATGGAYMGNGCNTAY TTYTTYGARATGGGNGCNTAYGAYCCNGGNYTNAARATHTGGGGNGGNGARAAYTAYGAR YTNGCNTTYAARGTNTGGATGTGYATHGARATHYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TGGMGNACNAARTGYTTYAARYTNGARAARGTNATHAARACN YTNTCNAAYCAYTGYGTNMGNGTNATHGARCARCAYGARGAYYTNYTNATHAARTTYAAR AARAAYCARGARCARTTYGAYCARYTNAARMGNAGYTGYTTYGARMGNGGNGARCARATH AAYCARGCNMGNGARGTNYTNGTNCCNATHTCNAAYGARYTNAARACNYTNMGNGARAAR TAYGARATHGCNGTNMGNTGYCARGTNGARGCNGARACNTAYGCNATHGARACNACNAAR ACNAAYAARAARYTNTTYMGNCARAGYCARYTNYTNMGNGCNAAYYTNCARGCNAARGAR ATHGTNGARATHAAYATHGAYGAYGARGARCARGGNGAYGARGARGARMGNMGNTAYATH GAYAARYTNGGNCARCARATHGAYGARYTNGARGARGARAARGTNGCNYTNAGYYTNCAR ATHAARACNATGAAYGAYAGYYTNYTNGARGARAARGARACNAAYGARCAYYTNMGNGAR AARTGYATGYTNATGAARGTNGARYTNCARCARTTYCARMGNACNGTNMGNCARCARGAR GARYTNTTYCARCARGTNGCNATHACNTCNGARAARGCNTAYYTNGARTAYCARGAYATG GARGARACNATHAARAARGARGTNTTYGTNMGNAAYGARGCNGARMGNGTNGCNCARMGN TAYCAYACNGARMGNGAYCARGCNMGNMGNGARAGYGCNATGGCNYTNAGYAAYGTNGCN GAYAAYMGNAARYTNACNGAYGCNATGYTNGARATHCARGARYTNAAYACNAARTCNATG GARATGAARGARGARTTYGARAARCARGTNATHGGNYTNAARGARCARYTNAARGCNGCN AARGARGTNTAYAAYACNGARACNYTNGTNGCNGARAAYGARGARYTNAAYGCNGARAAR AARGGNYTNCARGARMGNYTNGARAARAAYGARGARGARATGAARCARYTNAAYACNAAR TAYTGYGARYTNYTNGARACNTAYAAYTCNYTNGARAGYAARTAYCARCARGCNACNAGY CCNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNCCNACNAARAARGCNGAYGGN TTYYTNTCNMGNATHGTNGGNMGNAARGGNCARMGNGARMGNGCNAARGARAARYTNAAR AARGGNGGNGTNGARATHAAYGAYACNCAYTCNAARGCNGTNGAYGARATGATGAARMGN ATHAARAGYGGNAAYATHGGNYTNMGNCCNGTNYTNMGNAAR---------GGNACNCAR TCNYTNCCNGARAARGARGARCCNAGYGCNYTNAGYGARYTNCARGGNYTNYTNAGYAAR ATGAARAARTCNMGNAGYGARGAYGAYYTNTCNGCNTTY---GAYGAYATHGGNGTNGAY GARAAYTCNGARYTNGGNCARATHTTYAARAARMGNATHCAR------------------ ---------GARAAYGTNGARTCN------------------AAYACNAAYCARGCNAGY GARATGMGNCCNGTNCCNATGCCNMGNAARYTNTCNACNATHCARGAYGARGCNGARGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNGARMGNGARGAYGGNMGNGGNGAYMGN GAYMGNGAYNNNGARMGNGAYMGNGARAARGAYMGNAAYACNMGNAARATHGGNAGYGGN MGNATHACNATHGAYMGNGAYGGNGGNMGNGAYTTYTCNAGYYTNMGNGAY--------- ------------MGNGAYMGNGAYMGNGAYATHCCNTGGGGNMGNGAYMGNCARGARMGN GAYMGNGAYMGNGAYTGGGGNMGNGAYMGNGAYMGNGAY------GAYTGGGAYMGNGAY MGNMGNTTYGAYMGNGAY---MGNCCNGARMGNTTYMGNMGNGAYAGYGAYMGNGAYTTY TCNGAYMGNAAY---MGNGAYMGNMGNGAYTAYAAYMGNCCNTAYGARMGNCCNGGNMGN MGNMGNTTYTCNGARGARGARAARGARCCNGARTGGTTYACNGGNGGNCCNACNAGYCAR TCNGAYACNATHGARYTNMGNGGNTTYGARAGYGARAAYCARAARCAYCCNAAYGGNYTN MGNYTNAARAARGTNGARAAYTCNAARGGNAARGAYAARAGYTCNGCNAARGTNAARGAR ACNAARGCNGAYGARCCNTCNMGNAARGAYGTNGCNAAYGARCARGGNCCNGTNTCNGAY GARACNYTNMGNAARGTNCARCAYGCNGGNCARATGCARAAYCARGCNAARATH------ ------------------------AAYGCNTTYGAYYTNGAYGARTTYYTNAARGCNAAY YTNCCNYTNGAYGCNGAYTCNGARACNCARGGNAGYMGNTTYTCNMGNTTYTTYGGNCCN ACNGCNAAYACNTCN---------GGNGARGAYATGATGCCNAARGAYYTNYTNGARGAR AGYGTNTCNAGYTCNTCNATHCCNTCNCCNAARCARGTNTCNTCNAAYCAYCCNTAYTCN ACNGGNAGYATHCCNAAYTCNGCNGGNGAYAAYAAYGCNTCNYTNCCNCCNTCNGTNACN GCNYTNTTYAGYMGNGCNGGNCCNGCNGGN---TCNAAYGCNTCNYTNTCNAGYAAYAGY AGYTAYAGYGCNCARGAYGCNGARGCNCARYTNAARGCNATGYTNTTYGGNGGNCCNAAR GAYTCNGCNTCNTCNAGYGGNACNGCNTCNCCNGCNGGNGTNYTNCCNAAYTTYCARAAR MGNGTNAARACNGTNGCNGARYTNGARGCNGAYATGCAYCARAGYTCNCCNCAYAARATH GAR---------CCNCARTCNGGNCCNYTNGARGGNAAYAARGAYATGACNGCNTTYAAY AARTTYYTNATHATGATHAAYGCNGCNGCNGARGCNAAYCARAAYACNATHMGNAARGAR GTNTCNAAYACNTCNGTNCCNGGNTAYGGNATGGTNCCNAGYCAYAAYGARTTYTCNCAR GCNATGATGMGNAAYAARGARCAYCARYTNCARYTNCARCARCARTCNGTNAAYATGAAY CCNCARGCNATGTCNACNCCNCAYGCNACNGGNTCNTCNTCNGAYCCNATHYTNAAYYTN ATHCAYCARAAYCCNTCNATHGTNATGAARCCNGTNCCNCARTCNCCNAGYACNTCNGCN ATGYTNACNTCNCARCCNTCNGGNATHCCNGCNAAYGCNMGNGTNGTNTCNCCNYTNATG TTYAGYCARCARCCNCCNYTNCAYYTNAAYGCNCCNTCNCCNATHCAYCCNTCNCARATH TCNCCNGCNTCNYTNACNMGNTCNCCNGTNYTNCARMGNGGNTAYAGYCCNCARGARGTN GCNGCNCAYGCNCARGCNGTNGTNCARAAYACNYTNYTNAARMGN---YTNCARAAYCAR AGYGARMGNTTYAAYAARAARCARCARGARMGNGARAAYTCNCCNAGY------ATHAAR GTNGTNAARCCNCARCCNGCNGCNCARACNATHYTNCCNCCNACNCCNCARCCNAARGGN TCNACNGTNAAYACNTTYACNCCNACNTCNGTNYTNGTNAARATGCAYTCNGAYAARGCN ATGGARAARGARAARCARGTNCARGGNTCNATHGAYAAYAARGCNATGGAYTTYATGCCN TCNATGGARGARYTNGGNAAYGARGCNAAYATGCAYCCNATGGGNATHCCNAAYCCNGAY MGNTCNTCNCCNCCNCAYGAYGTNGARGAYGTNAGYTTYYTNGARCCNGTNAAYCCNAAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CCNCCNGARGTNGARTCNCCNYTNATGGARATGTGYAARAARYTNMGNGAR YTNTTYTCNYTNYTNTTYYTNTGYCCNYTNCCNGARAAYCCNCARYTNTAYGARTGYATH TCNCARYTNMGNGTNGCNATHAAYGCNGARYTNYTNGAYTAYMGNGARTAYYTNAAYGTN AARTCNCARMGNAAYATHGCNATGACNAGYTAYTTYGARAARTAYCCNGGNYTNATHCAY TTYATHTTYGTNGAYMGNMGNYTNCAYCAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AARATGAARMGN TCNGARMGNCAYATGAAYMGNYTNAARAGYATHATHACNAARGCNYTNTCNGARAARGGN GTNAARGARGAYGAYCCNATHCAYCARCCNTGYGCNAARAAYYTNYTNAAYGTNAGYGTN ATHYTNYTNAARACN--------------------------------------------- ---------------------------------------------------------AGY TCNTTYGCNTAYCCNACNATHAARGAYMGNAAYACNGTNATHGTNGCNAARATHGCNGAY TAYYTNAGYMGNAGYMGNGAYAGYYTNGTNCARMGNTTYGGNGGNCARCAYGCNGARGAY GARYTNAARACNATHATHGGNGCNATGTCNTGYYTNMGNCAYGARGTNATGACNAAYAAR CCNGCNATHCCNYTNAARGAYTCNTTYCARGAYTCNYTNGCNTGGAAYATHGARYTNGAY AARATHYTNAAYGGNGGNGARGCNCCNAARTGGTTYAAYAGYCCNTGGYTNYTNATGGAR TGYTAYYTNTAYMGNMGNATHAAYGARGCNGTNCARAARAGYTCNTTYTTYMGNAARYTN GAYGTNTTYGARGARCARAARCARAAYGCNTTYCAYGGNTCNTCNAARTCNATHTCNGCN YTNATHCARTAYYTNTAYGAYGTNATHAARGARYTNTCNYTNTGGGGNAAYAARTGY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARTGYTCNYTNYTNGGNATHGARAGYGTNYTNCARYTNTTYCARYTNAAYGAYAAY GARGCNATHYTNATGTGYAARAAYGTNGAYTGYACNTTYATGTCNTCNCCNACNTGGGAR AGYYTNGTNGTNCCNMGNGAYGCNTCNMGNYTNATHACNGARAAYTCNATHMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TTYATHAGYYTN CCNATHGTNGTNAARAAYYTNGGNGAYACNTCNAARATHGARTAYTCNGARACNGCNTCN CCNATHTCNGCNAARGTNGTNCARGGNAAY---ATGGGNTCNTCNGGNAARATHTTYYTN AAYGCNTCNGGNCARYTNAARCARGTNGTNGAYGTNAARGGNTTYGTNTCNTCNATGGCN AARGGNYTNGARACNGCNCARACNAARGTNAAYAAYAGYGARGCNGCNYTNCARGTNYTN GARACNGARGTNAAYYTNYTNMGNGARMGNGCNGCNYTNYTNGARMGNGARGARATGCAR MGNGTNTTYGARAARYTNAARGARGAYGARAAYMGNMGNATHGARCARGAYGCNGARGAR GARAARCAR---------------------------NNNMGNAARAARMGNAGYMGNAGY MGN------------GAYMGNAARMGNTCNMGNAGYMGNGARAARMGNMGNGAYGGNMGN ---MGNMGNAGYMGNAGYMGNGAYMGNAGY---MGNGARMGNMGNMGNMGNAGYMGNAGY MGNAGYMGNGAYMGN---------------------------MGNMGNMGNAGYMGNAGY MGNGAYAARAGYGAYAARMGNMGNGCNTAYAGYMGNAGYCCNGTNMGN------------ ---------------GARMGNYTNCCNGARYTNACNGTNGARGARMGNGAYGTNMGNACN ATHTTYTGYATGCARYTNTCNGCNMGNATHMGNCCNMGNGAYYTNGARGARTTYTTYTCN TCNGTNGGNAARGTNMGNGAYGTNMGNNNNATHNNNNNNAAYAARACNMGNMGNTCNAAR GGNATHGCNTAYGTNGARTTYGCNGAYCCNGARTCNGTNACNYTNGCNATGGGNYTNACN GGNCARAARYTNYTNGGNGTNCCNATHYTNGTNCARCCNTCNCARGCNGARAARAAYMGN GCNYTNCCNGCNACN---GCNCCNGCNCARAARCAR---GCNCCNGARGGNCCNYTNMGN YTNTAYGTNGGNTCNYTNCAYTTYAAYATHAGYGARGAYATGYTNMGNGGNATHTTYGAR CCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CCNAARYTNATGTCN CARGCNATHTAYGCNTCNTTYTGYTTYTGYTTYCCNGAYTCNTAYMGNCARTTYGGNGAR AGYTTYAARGAYGARYTNACNTTYYTNGTNTAYGGNTGGATGGCNGGNATHMGNCCNGCN CCNMGNAAYTGGATHACNTGGGAYATGAGYCAYYTNGARCCNCCNAAYYTNAARATGMGN GARGARYTNATGCARAARAARACNAAYAARAARATGACNTCNYTNATHGAYTTYGAYTAY YTNGAYTCNYTNATHTCNACNAAYGCNAGYCARTAYGCNTCNACNATGTCNYTNGCNCAR TCNGCNTCNACNGGNTCNAAYGTNAAYACN---------GCN---MGNAARCCNMGNATG CAYGCNMGNGGNAGYAAR---ACNYTNAARCCNACNTTYMGNACNTCNTCNCCNAAYAAR ACNCAYTCNCCNACNTCNTCNCAYGAYAAYAAYYTNATHGARGCNGTNGCNAAYGCNCAR AAYAGYCCNMGNTAYAARGGNAARGARAARMGN---AAYAGYGAYTTYTCNYTNACNCCN GGNAARGAYGGNAARMGNCCNAAYGARGCNYTNACNCCNATHMGNGARYTNGCNAGYGAR GAYGARGARGARGAYTTYGAYAARAARTTYTCNCARATHTCNATGAGYCARATHMGNGAY GGNMGNTCNAARAARGAYCAYGTNATHGARTCNCAYCCNYTNGGNMGNGGNTGYGGNTTY GTNMGNACNGCNTTYAAYGTNGARGGNAARAGYCCNYTNGTNGCNCAYTTYYTNCAYATG AARGGNYTNGCNCARGAYGTNGGNCARAAYATHTGGATHCARMGNGTNGARATHGAYAGY YTNCCNCCNYTNGAYGCNACNACNTAYATGGAYYTNATHGGNAAYTCNTCNAARACNATH AARAARYTNGARTCNGGNTTYCARGARATGTAYCAYAARAAYTAYAARGCNAGYCARAAR TTYATGAARCAYCARCARAARATHYTNMGNGARCAYATGCARAARCARTCNGCNYTNYTN GCNAAYAARGARGARGTNAARGTNYTNTGYGAYYTNATHATHYTNGAYCARMGNAARAGY CARGAYTCNGTNTCNGCNGGNGCNAAYGCNGCNATHGARGCNGCNYTNATGGCNCARGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNCCNGCNTAYYTNAAYAARACNTCNGTN MGNCCNGGNYTNAARAAYTGYGGNGAYGTNAAYTGYATHGGNMGNATHCAYGCNTAYYTN GARGCNATHGGNGCNATHAAYTTYGGNTGYGARCARGTNTCNTAYAARAAYCCNCARMGN AGYTCNTTYGGNGGNCARAAYAAYMGNTCNAARGTNYTNAAYAARGARTTYATHACNTCN GTNACNAARCCNAARTCNGARTTYCARMGNCCNMGNAARMGNMGNATHAARGAYGARAAY GGNATHTGGGTNGAYGARAARGARYTNGARGGNAARACNATHGARCAYGGNGTNGTNGAY AARGAYMGNAGYCARGTNAARAARTCNMGNAGYGCNAARCAYGCNTAYAAYCCNTTYAAR YTNGTNCCNTGYYTNCCNTTYGGNGARGARAAYATGGARCCNTAYAARATHGARATHTTY AAYACNGCNYTNTCNATHATGGAYATHCAYTCNCAYATHTCNAARACNGARGTNATHGGN ATGYTNGGNGGNCARTTYGAYYTNTGYMGNAAYTGYYTNATHGTNAGYATGGCNATHCCN TGYAARAGYATGAGYACNGGNATGCARTGYGARATGGAYCCNGTNTCNCARACNCARGCN AGYGARCARATHGARGARATGGGNATGTCNGTNGTNGGNTGGTAYCAYTCNCAYCCNACN TTYGTNCCNGAYCCNTCNGTNMGNGAYATHGARACNCARCARAARTTYCARTAYTGGTTY TCNAARGGNGGNAAYCAYTTYGTNGGNATHATHGTNAGYCCNTAYAAYCCNTCNTCNMGN TCNGCNTTYTCNGAYATHTGYTGYYTNACNATHAGYGARGARTTYAAYTCNGARTTYCAR TGYAAYAAYCCNTAYAARTTYGAYTAYCARATHGTNTAYAARGAYAAYCCNMGNGARATH YTNGGNCCNGCNAGYGARYTNGCNGARTAYATHGARTCNTGYGGNGCNCAYAARGCNGGN GTNGCNAARATHGTNCCNCCNAARGARTGGGTNCCNMGNAARAGYGGNTAYGAYGAYATH GAYYTNGTNATHCCNGCNCCNATHGARCARATHGTNTCNGGNCARCARGGNYTNTAYACN CARTTYAAYGTNCARAARAARGCNATGCAYGTNAARGAYTTYAARAARYTNGCNGARTCN TCNMGNTAYMGNGCNCCNAAYCAYTTYGAYTAYGAYGAYYTNGARMGNAARTAYTGGAAR AAYATHACNTTYGGNCARGCNATHTAYGGNGCNGAYATHAGYGGNTCNATHACNGAYAGY GAYCARGAYGTNTGGAAYATHAAYMGNYTNGGNTCNATHYTNGAYCAYGTNAARACNGAY TAYAAYATHAARATHGARGGNGTNTCNACNGCNTAYYTNTAYTTYGGNATGTGGAARACN ACNTTYGCNTGGCAYACNGARGAYATGGAYYTNTAYAGYATHAAYTAYYTNCAYTTYGGN GCNCCNAARTCNTGGTAYGCNATHCCNCCNGARCAYGGNCARMGNYTNGARMGNYTNGCN TCNGGNTTYTTYCCNAGYAGYTTYGGNGARTGYCCNGCNTTYYTNMGNCAYAARATGTCN YTNATHTCNCCNCAYATHYTNAARAARTAYTCNATHCCNGTNAAYAARATHACNCARGAR GCNGGNGAYATHATHATHACNTTYCCNTAYGGNTAYCAYGCNGGNTAYAAYCAYGGNTTY AAYTGYGCNGARTCNACNAAYTTYGCNTCNGARMGNTGGATHGARTAYGGNAARMGNTGY YTNCARTGYGTNTGYMGNMGNGAYGGNGTNAARATHCAYATGGAYGTNTTYGTNAARAAR TAYCARCCNGARMGNTAYCARYTNTGGAARGARGGNAARGAYYTNGCNCCNCAYCCNGAR GGNCAYMGNGAYGCNAGYMGNCCNYTNGGNGGNMGNGGNYTNAARAARAARATHGARGCN AAYAGYTCNGGNACNGCNCAYTCNMGNMGNCAYCCNYTNAARGARGARTTYAAYACNCCN TCNTGYAAYGCNGAYACNGTNGCNACNTCNGAYGARCCNAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MGNGGNGAYACNTTYGTNGCNGAY YTNGTNGCNGGNYTNACNGTNGGNYTNACNGTNATHCCNCARGGNYTNGCNTAYGCNTCN ATHGCNAAYYTNCCNCCNCARTAYGGNYTNTAYTCNGCNTTYATGGGNTGYTTYGTNTAY ACNATHATGGGNACNTCNAARGAYATHACNYTNGGNCCNACNGCNATHATGTCNYTNATG ACNGCNGARTTYGGN---ATHTCNCCNGTNGAYGGNGAYCCNACNGTNGCNATHYTNYTN ACNYTNATHTGYGGNGTNGTNCARYTNYTNATGGGNYTNYTNCARYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TCNYTNGTNYTNGAYGARCARACNCARAARGTNAARTGYAAYYTN ACNAAYCAYGARATGCCNGCNAARGTNGCNGCNATHGARAGYTAYGTNAARGGNAARAAR TAYAARMGNYTNGCNGAYYTNGAYGCNYTNGTNTAYGARGARCAYAARCARCAYATHGTN CCN------AAYAARAARMGNGARAAYGARATGTTYTGYYTNYTNACNYTNMGNCAYYTN GARAARACNGCNTCNGCNATHCARMGNCAYYTNAAYGGNAARAARTTYAARAAYGCNYTN GCNMGNTGGAARAARTGYCARGARAAYGGNGARAARTTYATHGCNAARGCNATHGCNGAR GCNGARGAYMGNGAYGARGAYGAYATGAAYAGYGTNGARAGYGGNGAYGARTCNTTYGAY GAYGAYGARGCNGGNGARGARGAYGARGAYGAYATGAGYGAYYTNTAYCCNGCNGCNGAY TTYCARGARGAYAGYTCNGARGARGARCARAAYGAYGAYGCNGARGAYGARAARGARACN ATHCCNTCNCCN------------------------------------------------ ------------------------------------------------------------ ---------CCNATGTTYACNGGNTCNATGGGNYTNCCNATHGTNGGNGARACNYTNCAY TTYYTNGCNAARGGNTCNTCNTTYTAYGCNGARAARGCNAARAARTGYGAY---ATHTAY AARACNCAYYTNYTNGGNAAYCCNGCNGTNCARGGNACNGGNGARGAYGAYATHTTYATH YTNATHGARYTNGARTGGAGYYTNYTNMGNGTNAARTGGCCNGCNTCNGTNAAYATGYTN ATGGGNTCNAARMGNGTNACNACNYTNGTNGGNYTNGARCAYGCNMGNYTNAARTCNGAY YTNAARMGNGCNTTYACNCCNACNMGNYTNGCNGAYTAYTTYGAYTGYGTNCARAAYCAY GTNTGYAAYCAYATHAARCARTGGACNGARGARGGNYTNYTNAAYMGNYTNGTNATGGGN TTYCCNGCNTGY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATHYTNGCNTGYTTYMGNGAYYTNCAYMGNGCNMGNMGN GARGTNTTYGCNGGNGAYATHAGYGCNYTNAAYAARGTNMGNTCNCARATHAAYACNGAR TTYMGNGARAARYTNAAYGARACNGAYGAYTCNAARATHGARGARAAYTTYGTNYTNGCN MGNGAYGTNGCNTAYYTNYTNMGNTCNACNGTNGTNCARYTNCARCARAAR------GAR GCNGARACNTAYGARYTNMGNATHACNAARAAYACNCAYYTNCCNGARAAYACNCCNTTY GAYCCNAGYAARGARATHCCNGTNMGNCCNAARAARMGNAARGGNTCNAARTGYTCNGAY AGYTCN------MGNTTYYTNGTNAARGCNAARGARATGAARGARTTYTTYMGNYTNACN GARGAYTCNATHATHAAYGAYTTYYTNAARATGGAYAGYTGYAARMGNATHGCNGAYAAR TAYYTNYTNGCNATGGTNTTYGCNTAYTTYAARMGNGCNGAYTAYTCNYTNAARGAYTAY ACNMGNTCNAAYTTYTTYGTNGCNYTNTAYYTNGCNAAYGAYGTNGARGARGAYGARGAR GARATHAARTAYGARATHYTNCCNTGGGCNYTNGGNAARGARTGGMGNGARACNTAYGTN GAYTTYYTNAARGARMGNGAYYTNYTNTTYMGNMGNATHGAYTAYAARGCNATHATHAGY MGNMGNTGYTGYGAYGARATHATGAAYATHGARCCNAAYAAYATHYTNTGGAARMGNGAR MGNYTNCARCAYCAYGCNGGNGCNGTNMGNMGNTAYATGAARGAYCCNAARGAYAAYGGN ATHCCNMGNGGNCCNGAYGCNAGYCCNTGGATGTGYCCNGAYTGYGAYACNAAYGAYAGY CARTAYGAYTCNTCNAGYTCNACNAGYYTNAGYTGGTTYATHTCNTCNAGYAARTCNCCN ATGGAYACNGTNTTYGTNCCNTGYYTNAARTGGYTNGAYTCNGARMGNGAYGARATGAAR ACNYTNGGNTGYYTNGCNGTNGGNAAYTTYGCNMGNMGNGAYTCNTAYTGYGTNGARYTN GTNAAYAAYGGNATHGTNGARAARYTNYTNCCNYTNYTNAARTCNGGNCCNGAYGARTCN TTYTAYYTNCARCAYGCNGTNYTNAGYACNYTNMGNAAYYTNGCNATHCCNGTNGCNAAY AARCCNMGNYTNYTNGARYTNAARGTNATGGARTCNTGYYTNTGYYTNGTNAAYTCNGAR GTNATGGCNGTNATHTTYAARYTNYTNGGNYTNYTNMGNATGYTNATHGARGGNCARGAR TCNGCNGCNATHAARYTNGGNCARGARMGNGGNTTYYTNGAYTGYYTNTCNGARTGGTGY AAYGTNGARGTNCAYGCNGGNGTNAARGGNGARGCNCCNMGNGTNATHGCNTCNYTNATH AARAAYAGYMGNTCNYTNGTNGTNATHCARAAYYTNATHMGNGCNAGYTGYGTNGGNCAY YTNGTNGCNATGGCNCARAGYGARCAYCAYGTNATGCARAAYGARGCNYTNGTNGGNYTN ACNGCNATHTGYAGYACNGCNCCNGGNGAYGCNGCNGTNTCNYTNAARGARGCNGARYTN CCNCARACNATHATHAARYTNYTNAAR---------------------ATGACNAAYTGY CAYMGNYTNTTYYTNCARAGYYTNGTNTCNCARGGNATGATGAAYCARAGYGARATHAAR TCNTGYTAYGTNAARAGYAARAAYMGNTTYGCNGARCCNTAYGARMGNGARAAYATHTCN GCNYTNGTNATHGAR---------------TTYGTNMGNACNGTNAAYGCNGCNATHTCN CCNTTYCAYYTNGARATHAARAARGGNATHCARGARCAYGAYGGNYTNAGYGTNTAYTGY YTNGTNAAYACNGTNGARAGYCCNATHTCNMGNYTNTCNTCNTCNTAYTCNAARAAYGAR YTNGARYTNTTYAARAARYTNGTNGARTTYATHGTNGARTCNAAYGAYGGNAARATHGGN TCNMGNATHGCNYTNAAYYTNACNGARAARYTNGARAARMGNATGGGNAARGARGARGCN CARAAYTTYTTYAAYMGNYTNGARAGYCARAARTGGGTNGTNAARGAYGARAAYGGNAAR ATHTCNYTNTCNGTNMGNACNYTNYTNGARYTNGAYCARTAYYTNCARGAYATGTAYCCN TCNYTNATHAARAARTGYAAYYTNTGYGAYAARATHTGYATGCARGGNGARTCNTGYGAR AGYTGYGGNGTNMGNATHCAYATHAARTGYTCNAARACNTAYTTYTCNAARCAR------ ------------------------------------------------GAYATHACNGTN CARAARCAYCARMGNAARGGNAGYGGNAAYGTNMGNCAYCARTTYGTNMGNYTNYTNATH AAYGTNAARGTNCARTGYTTYGAYGAYGTNTTYGARYTNAARGCNAARACNYTNCCNTTY TAYYTNTGYACNGGNGCNYTNCARGARYTNGARYTNATHGGNATGMGNATGTGGTAYTGY AGYAAYACNGAYATGTAY---GGNCARTGYGTNTTYCAYAARGARYTNAAYACNAARGAR TTYYTNGAYATGYTNGAYATGMGNATHAGYGTNTGYGGNGAYMGNGARMGNGGNYTNTCN AAYGAYGCNMGNCARTTYATHGTNTCNMGNATHAARTCNAAYGAYMGNAARATGATHTCN GARCAYTCNTTYGTNAAR------------GCNAARYTNATHAARTTYGAYGARAGYGAR AARAGYTTYAGYTTYTTYACNTGGTTYTAYGCNYTNGTNAAYACNATHGARACNCAYYTN YTNCAYCAYTGGTGYAAYGGNGTNATHTAYGAYYTNATGACNAARGARGARGCNMGNCAR GTNYTNYTNAAYGARGARGTNCCNTTYTAYACNGCNYTNATHMGNCCNTCNAAYTCNTAY GTNAARAARCCNAAYTGYACNGARGCNYTNGTNAARYTNGTNGTNGARATHAARATHCAR ACNGARGGNGCNGARAGYATHGARGGNGTNCAYATHGCNATGAARAAYGTNAARCARCAR GGNTTYTAYAARGTNYTNCARAARATHGARTTY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATHCCNCARTAYCAYCARAGYTGYGTNTAYYTNGTNGAYYTNATHCCNYTNACN CCNMGNGGNAAYTAYYTNCARGGNMGNYTNAGYTTYATHTGGYTNTGYYTNACNYTNGAR CCNAAYCARGCNGAYGARATHGAYTTYGAYYTNGARAAYATHTCNCCNGTNATGATHACN CARYTNGGNCAYTTYCCNAGYGAYGCNAAYAGY---TCNAAYYTNTAYTCNGCNYTNCAY CAYYTNATHAARACNGAYGCNAAYAARATGGAYTCNGTNYTNACNYTNYTNGAYMGNGCN GTNGGNGAYGARAAYAAYMGNTCNATGCARTCNAARGARGARYTNCAYTAYYTNATHGAY CARGTNAARCAYGTNAARMGNGAYATHMGNGAYAGYATHAARATGYTNGARYTNACNAAR GTNAARGAYAARATGTCNATHATGATHGCNAARTGG---YTNATGACNGCNCARAAYACN AARGARGTNCARMGNAGYATHTTYTCNTTYGTNACNTCNTCN------CARGTNGTNYTN CCNGARGARAARYTNAARGAYGTNTCNACN---------------------ATGAGYGGN MGNAAYMGNAARGTNMGNGTNTGGGGNMGNYTNAARCCNACNGCNAAYTTYGCNTAYGAR AAYYTNGARTTYYTNCCNGAYAAYAARGGNATHAAYGTNCAYATGMGNMGNGAYCCNAAR AARGGNGTNGTNAAYAAYCARATHYTNGAYTGGTCNTTYAARYTNGAYGGNATHTTYAGY AAYGCNGAYCARGAYGTNGTNTAYAAYACNGTNACNTCNGAYATHGTNTCNAGYTCNYTN GAYGGNTAYAAYGGNACNYTNATGTGYTAYGGNCARACNGGNGCNGGNAARACNTTYACN ATGACNGGNGCNACNGARAGYTAYMGNCAYMGNGGNYTNATHCCNMGNGCNATHTCNCAR YTNTTYMGNCARATHGARGAYMGNYTNGARTAYAGYATHAGYGTNMGNATHTCNTAYATG GARATHTAYAAYGARCARATGTTYGAYYTNYTNGGNAGYTTYCCNGAYCCNAAYTGGAGY AAY------AARGAYATHAGYAAYCARYTNGAYCCNATGGTNATHTCNGARAAYCAYGGN GGNGTNTTYGTNAARGGNYTNTCNTGYCAYYTNGCNCARAAYGARGARGARGCNYTNAAY YTNYTNTTYGARGGNGARACNAAYMGNTCNATHGCNGCNCAYTCNYTNAAYAARCARTCN TCNMGNTCNCAYTGYATHTTYACNGCNTAYATHGARTCNMGNTCNMGNGTNCARTCNAAY GCNAARTAYACNGTNTCNAARYTNAAYTTYGTNGAYYTNGCNGGNTCNGARMGNYTNAGY AARACNAARTCNGARGGNAARACNAARGARGARGCNATGTAYATHAAYAARTCNYTNTCN TTYYTNGARCARGTNGTNGTNGCNYTNGCNTCNAARAGYMGNGAYCAYGTNCCNTTYMGN CARTCNAARYTNACNCAYTTYYTNAARGAYTCNATHGGNGGNAAYTGYAAYACNGTNYTN ATHGCNAAYATGTGGGGNGARAARCCNCARYTNGARGARACNGTNTCNACNYTNMGNTTY GCNACNMGNATGATGTGYGTNGCNAAYGARCCNGCNAARAAYGARATHTAYGAYCCNGCN YTNYTNGTNAARAARYTNCARAARGARATHAGYCAYYTNAARTCNGARYTNGCNATGCAY GAYACNYTNACNAAYMGNAGYYTNGTNTCNTAYGAYGCNYTNTCNGARCARCARAARTAY GARATHMGNACNCARGTNAARMGNTAYYTNGARGGNAGYYTNGAYGARATHGAYATHATH AAYATHMGNCARATHGTNGGNTGYTTYGARACNTTYMGNGARACNTAYAARGAYATGGAR AARGARATGGARGCNAARYTNMGNGAYAARTAYATGYTNATHGAYAARACNGAYCCNAAY TCNATHGCNGCNGCNCARCARAAYATHGARMGNYTNGTNMGNTCNAARCARGARTCNATH TCNAARGCNGGNGTNCCNATHGCNGAYGAYGGNTCNTTYGTNGGNGARYTNGAYGGNGGN GGNTTYGGNGTNGGNGCNGCNCCNAARYTNTCNAARCCNGAYATHTCNGCNGTNGTNCAR YTNAARAARAARGARMGNGARMGNGAYMGNAARMGNGGNTCNMGNGGNGCNAAYAGYCCN ATHGCNGGNAARACNTCNTCNAGYCCNTCNCARAGYYTNAARGGNGARMGNAARGTNGAY TCNCCNCCNACNCCNGTNGGNGARMGNGTNGARAARGARCARCAR------GARGGNTCN GCNTCNCCNGTNAGYTCNACNGGNAAYATGTCNMGNCARGAYMGNAGYCARMGNCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATHTAYGCN CARTTYGARCARYTNTAYGTNAAYYTNTGYMGNATHAGYTTYGTNTCNAAYYTNACNAAR ACNGAYGAYGARGCNGAYYTNTAYTCNGTNCCNTCNGGNCCNAGYGARATHYTNYTNCAR GARATHCARGCNYTNAARGARAARGTNAARTAYYTNGARAGYTGYMGNMGNGARAGYAGY TCNGTNCAYAGYCARGAYTCNAGYGCNAGYCCNGGNGAYGGNGAYAGYGCNTGYCCNCAY CCNAAYCCNTGYYTNGAYGTNCARCARATHTCNTCNACNTTYGARTGGACNATHGAYCAR TAYTAYGARMGNYTNGARMGNGARCARAGYGGNMGNATGACNCAYACNGTNTCNGARCCN TTYTAYATHAGYCARTTYGGNTAYMGNGTNTGYYTNGAYGCNTAYYTNAAYGGNAAYMGN CAR------AGYMGNTGYATGTCNYTNTTYYTNMGNGTNGTNAARGGNGAYTTYGAYGAY YTNYTNCARTGGCCNATGTCNTTYAAYYTNACNTTYTTYGTNGTNAAYCARACNGARAAR GGNTCNGTNMGNTTYGGNTCNMGNGAYAAYCCNYTNAAYTCNYTNCCNTAYGGNCARCCN GARGARGARCAYAAYGAYYTNACNCAYTCNTGGGGNATGATHCARTTYATHGGNCAYGAY GTNATHAAYTCNMGNTCNTTYGTNAARAAYGGNGCNGTNAARATHMGNGTNAARATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GTNTCNCARAGYCCNAAYAARTTY------YTNGCNATGGAYYTNCCN AARAAYGARCCNGTNCARCARGARATHGGNGAYTTYAARGAYYTNYTNYTNAARTGYGTN GGNGAYYTNGAYYTNGTNYTNGARGTNTAYTAYTCNCCNGCNACNAAR---AARYTNYTN GTNMGNYTNAARGAYAAYATHCARMGNTCNGTNYTNGARAAYTTYAARCCNAARAGYTCN GARYTNYTNGARGTNGAYACNCARGGNAARGTNAARGGNATHGGNATHACNYTNATHGGN TCNGARGTNAAYGGNTGYGTNGAYACNGAYMGNAAYGTNTAYGAYTTYGTNTCNMGNTAY TTYTCNCCNTGGAAYGGNATHCCNGARGAYCCNGTNACNGGNTCNTGGCAYACNGTNGCN GGNCCNTAYTGGTCNAARCARGTNAAYAARTCNGARYTNTAYGCNMGNCARTGYTCNACN MGNGGNGGNGAYYTNCARYTNCARGTNAARGAYGCNYTNGTNACNGTNATGGGNCARGCN GTNATHAAYYTNAARGGNAAYTTYTAYYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CAYTTYCCNAARGGNGGNCARGARGGNAAYYTNCCN ACNYTNATHGARAARTGYYTNYTNCARTTYCARACNGAYGCNMGNTAYYTNAAYGAYCCN MGNTTYATHAARYTNTGGATHATGTTYTCNAAYTTYGCNGARTCNCCNACNGAYYTNTTY TCNTAYATGTTYGAYAAYGGNATH------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGGNAAYGGNATG AAYAARATHYTNCCNGGNYTNTTYGTNGGNAAYTTYMGNGAYGCNAARGAYYTNAARCAR YTNGARGARAAYAAYATHACNCAYATHYTNTCNATHCAYGAYAAYGCNAARAARATHYTN AARGAYAARGARTAYYTNTGYATHGARGCNGCNGAYAAYTCNGAYCARGAYYTNTCNAAR TTYTTYCCNCARGTNAAYAARTTYATHCAYAARGCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNGARCARYTNCARGCNMGNACNGGN AARGAYCCNGTNGGNYTNCCNGTNCARYTNAAYTCNAGYGTNGAYTTYGARTCNCAYTCN GARAAYGCNAGYGAYGAYCCNGTNATHGARATHACNATHTCNTGYAGYMGNYTNCCNTGY GAYAGYGCNGAYYTNCCNCCNAAYCCNYTNGTNGTNGTNCAYACNYTNYTNCCNCCNCAR CARCARACNTGGYTNCAYCAYAAYCAYACNGARATHGTNGARMGNAARAAYGAYCCNCAR TTYYTNAARACNATHGGNTTYGGNGAYMGNCAYGGNGTNGAYACNAGYACNMGNGTNMGN YTNATGGTNCAYCAYGTNGTNGARMGNATGACNATGTCNYTNYTNGGNCARGCNATHTTY ACNYTNCARCARGTNYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNTGGCCNGAYGCNAARGTNGARATHTTY GGNAGYTTYMGNACNGGNYTNTAYYTNCCNACNAGYGAYATHGAYYTNGTNGTNTTYGGN AARTGGGAYGCNCARCCNYTNTGGACNYTNTAYAAYGCNYTNGTNAARGCNGGNATHGCN GAYGCNGCNTCNATHAARGTNYTNGAYAARGCNTCNGTNCCNATHGTNAARYTNACNGAY GCNGARTCNGARGTNAARGTN------------------AAYAGYAARMGNGAYATHGCN AGYGCNAAYTTYGTNATGCAYGARATGCAYTGYAARMGNCAYATHGTNYTNTGYGAYAAR TGYGAYGARCCNATHCCNMGNTCNGARYTNGARCARCAYTTYACNGAYATHCAYATGAAR GTNCCNTGYGARYTNTGYAARATGGARGTNGCNAARGARGARATGGARAAYCAYMGNGAY AAYYTNTGYMGNAARAARATHAARATHTGYGARTAYTGYGARYTNTCNGTNGCNACNGAY GARYTNGARGCNCAYAGYGAYTAYTGYGGNAGYMGNACNGARTCNTGYGAYYTNTGYCAR CARTAYGTNATGYTNAARGAYATGACNCARCAYCARYTNTCNGGNTGYACNTAYCCNGAR CCNAARCCNCCNGCNCCNCARYTNGAYGCNGAYCCNTTYAGYATGTCNAAYYTNCAYCAR TTYYTNGAYTCNGGNMGNYTNGAYAGYCAR------ATHCCNGAYTTYACNGCNAGYYTN MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNTCNYTNGGNMGNAARCCNGGNGAYAARGAYGGNCCNATHYTNYTNATGYTNTGY ACNTCNAARAAYMGNAAYGGNGAYAARTTYAARYTNMGNMGNAAYGTNGARAAYATHTTY TAYAARTTYYTNAARGAYGGNAARGCNACNYTNMGNYTNACNGARCCNCCNMGNGAYATH GCNTTYAGYAARGTNGAYCCNTCNCARYTNAAYATHTTYYTNAARATHGTNAARYTNACN AGYGARGGNAARGARTGYCCNTCNAARGCNYTNAGYATHYTNGCNCCNGTNTCNACNAAR CARYTNGARAARCCNGCNACNAGYYTNGTNGTNTCNAARCCNTCNGARTAYCCNATGTCN YTNCCNAARACNYTNGARMGNYTNACNATHAAYGARTGYYTNYTNMGNMGNGTNAGYCCN CARATHATHTCNATHTCNAGYYTNAARGARYTNGAYYTNGGNTAYAAYCARGTNGCNTGY YTNCCNGAYTCNTTYAGYGARYTNACNTCNYTNACNAGYYTNYTNYTNCCNTTYAAYAAR YTNACNGCNTTYCCNGTNGTNYTNYTNCARGGNACNYTNCCNAARACNYTNTGYGTNYTN GAYYTNMGNCARAAYGARATHGTNGGNYTNCCNGCNGAYATHGTNAARYTNAARMGNYTN CAYACNYTNAAYYTNAGYAAYAAYCAYGTNMGNGCNGTNCCNGARTCNYTNGGNATGATG GCNTCNYTNTAYAAYATHMGNATGTCNAAYAAYAARYTNGAYTTYYTNCCNGGNAGYTTY YTNATGAAYAGYTTYGARACNGTNGAYTTYAGYGARAAYCCNTTY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ACNAAY YTNGARAARGGNAARGTNTCNTCNTTYGTNCARYTNMGNGGNTCNGTNCCNYTNTTYTGG TCNCARGAYATHTCNAARATGGTNCCNAARCCNCCNATHTCNYTNGAYCARMGNGAYCCN TAYTGYAGYGCNGCNGGNATHCAYTTYAAYCARATGYTNTAYMGNTAYGGNTCNCCNATH ATHGTNTTYAAYYTNGTNAARACNMGNGARAARAARMGNCAYGARAGYATHYTNAGYGAR GAYTAYGTNAAYACNATHGARTAYYTNAAYCARTTYYTNCCNGCNGARCAYCARATGCAR TAYATHGGNTTYGAYATGGCNMGNGTNAAYAARMGNAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYGGNYTNYTNGAYGCNMGNCCNCCNMGNGARACNGARGAY AAYMGNGGNCCNMGNAARATHAGYGAYTCNTAYGARAAYGTNCCNGARTGGGCNGGNGAY GAYGTNGGNGAYGAYCCNGGNACNTTYGAYTCNAARGGNGTNTTYGTNTCNAAYMGNATG AARATGACNGARTCNGARAAYYTNYTNCARATGGARAARTCNYTNCARAAYYTNATHGCN GGNATGACNGCNAAYCCNGARACNAARCCNGARGARGARGTNGAYGTNTCNAARAGYGCN YTNCCNYTNTCNCAYAARGAYGCNAAYAARTGGTTYTAYMGNGAYCCNCARGGNAARATH CARGGNCCNTTYAAYAGYGARAGYATGGCNGARTGGTTYMGNATHGGNTAYTTYACNATG AGYYTNATHGTNAARMGNGGNTGYGAYGAYTCNTTYAARCCNYTNGGNGARYTNATHAAR CARTAYGGNMGNGTNCCNTTYGTNCCNGGNCCNCCNYTNCCNCCNYTNATHACNACNAGY YTNCCNGARGARGTNGTNACNACNATHCCNTCNYTNGTNTCNCCNYTN------ATGCCN GGNATGATGGGNCCNACNATGCCNTCNYTNCAYGAYMGNTTYYTNTTYMGNTCNATGATG YTNCARGARCARCARCARTCNCARGAYYTNCAYCCNCARGTNCAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GCNGGNAARTTYAAYTAYAAYGARCARAARAARCARYTNGCNGARGARMGNMGNMGNGAR TAYAAYGARYTNYTNCARCARAARGCNAAYCCNGTNAGYAARGARAARGARCCNGARATH GAYAAYCCNTCNATHATHCCNTTYAAYMGNCCNGAYCARGARMGNYTNAARATGAARATH YTNGARGARGARMGNCARMGNGARTAYAAYCARACNAARGCNCARATGGARGAYAARACN MGNMGNMGNGARGCNACNCCNGTNAAYCAYTTYGAYCCNTCNGCNYTNGARCARGARAAR MGNYTNCARAARGARMGNGARCARMGNGARTAYAARGCNATGYTNGAYAARCARCARGAY TAYCARAARAARATGATGYTNYTNCARCARGGNGTNCCNTAYGARMGNATH--------- ------------------------------------------------------------ ------------------------------ATGCARGCNTAYAGYCCNCCNYTNTCNYTN TGGGGNYTNATHGARCARCAYGTNCCNCARTTYGARYTNGARGARATHAARTAYATHYTN GGNTCNCAYATHGTNGAYCARAGYYTNGARYTNCAYAAYGARATHGARATGYTNYTNGAY ATHTGGMGNGAYATHMGNGAYGARACNCARGARTCNAARYTNATGCARTCNMGNYTNCCN GARCCNCCNAAYCARMGNGARMGNYTNGTNCARGARATHAAYTTYTTYGCNGARAGYATH AARGAYAARGCNAARAAYAARGGNATHGAYCCNAGYAAYATHYTNAARCAYCAYAAYAGY GAYGTNATHGAYTAYGCNTCNGAYYTNAGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GCNAAYGTNACNGARTTYTGY AAYAAYGCNAAYGARGARTAYGTNAARGARAAYTAYCARAARGCNGTNAAYYTNTAYACN GARGCNYTNGCNYTNGAYGGNAARMGNGAYGAYATHTAYTGYTTYMGNGCNCARGCNTAY YTNTCNYTNGAYAAYTCNGAYGCNGCNATHAARGAYTGYGAYGARGCNATHAARYTNAAY CCNCARAAYCARAARGCNTAYYTNAARAARGGNTCNATHYTNYTNAAYATGAAYGARGTN YTNCAYGCNGARAGYGTNTTYAARGARGGNCARAARCARTGYACNGGNGARAARGARTTY YTNGAYTGGATHTGYAARGTNGARAGYMGNATG---------------------AARGAR YTNGGNATHGGNCAR------------------ACNCARCARCCNCCNATHYTNAARCAY AAYTGGTAYCARACNCAYACNCAYGTNATHGTNAAYGTNATGGTNAARAAYGTNAARAAR GARGAYYTNYTNYTNGAYGTNGARAARMGNTCNTGYAARGTNAGYATHAARMGNGGNGAR GARTCN---AAYGAYYTNGARYTNACNYTNGCNCAYTCNATHGTNCCNGARCARACNCAR TCNAARATHTTYTCNACNAARATHGARATHAARYTNAARAARTCNGARGGNATHCARTGG ACNAARYTNGARGGNCCNCARGARGARGARAAR---ACNGTNYTNCCNCCNTGYGCNGCN CCN---GARGTNGTNGARGCNCCNMGNTAYCCNAGYTCNTCNCAYCAYTCNMGNGAYTGG GAYAARYTNGCNGCNGARGTNGTNGARGARGARAARAAYGARAARYTNGARGGNGAYGCN GGNYTNAAYCARTTYTTYCARAARATHTAYGCNGAYGCNTCNGAYGARACNAARMGNGCN ATGATGAARTCNTTYTCNGARTCNGGNGGNACNGTNYTNAGYACNAAYTGGAGYGARGTN GGNAGYCARAARGTNGARGTNAARCCNCCNGAYGGNATGGARTTYAARAARTGGGAR--- ---AARATGCCNAARMGNAARGCNACNGAR------------------------------ ------GARACNACNCCNGCNCCN---GARTCNCCNAARAARGCNAARGARGAYGCNCCN AARAARGCNMGNGGNMGNGGNMGNCCNCCNYTNTCNGCNGARGARAARGCNAARMGNGAR GARAARAARAARGCNTCNTCNGGNMGNGGNMGNGGNMGNCCNAARGGNTCNACNAARAAR TCNAARAGYAARAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNGARMGNYTNTAYTAYTGGGCNGARTTYGCNGTNGARCCNYTN MGNTCNTAYGCNACNGGNYTNYTNAGYGGNGCNATGGARYTNAAYGAYATGGCNATHAAR TTYMGNGAYGARAGYATHCAYACNGTNCCNATHATGYTNGAYMGNYTNCAYGCNYTNATG ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNGARAAYGAYTTYGTNAAYGTNGTNGARTTY GCNGARACNGCNAARTTYGTNAGYAARTGYTTYAAYCAYACNGCNTTYGTNCARGCNAAY TAYMGNAAYAARAARCARYTNGARAAYGAYGTNGAYAARYTNTCNGCNYTNGGNCARGCN GAYTTYAGYGARGCNATHACNTTYAARAARTTYGARGARTTYAGYCARAAYGARACNAAY GAYGARAAYAAYATH--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNGTNGARGAYTTYGCNGGNTTYYTNYTN TCNTTYCARGCNGTNGARTGYMGNTGYTTYTCNACNAAYTTYCARTAYACNCARATHMGN MGNTTYYTNMGNCARATHGARATGAAYTGYGGNACNTCNGTNAAY---ACNTAYCAYMGN GCNYTNMGNGCNYTNTCNACNTGGTCNACNGTNTCNCARGARGGNAARYTNGARGGNAAY YTNMGNGARMGNYTNACNGGNATHYTNAARAAYATGCCNGGNGTNYTNGAYAAYYTNGTN AGYTAYTTYYTNGAYGGNACNATGTCNGAYTGYYTNTCNATGGAYTTYGARGAYATHTGY YTNGAYGGNGAYGAYGCNATGAARGAYGAYGAYGAYGGNTTYGARGTNGTNTCNGTNGTN GAYGARAARGAYGAYTAYAAYACNAARACNTGYCCNTGYCARTGYCAY---AAYAAYTCN GCNGARMGNAARTTYMGNYTNMGNCAYMGNCAYTGYATHTCNTGYAGYYTNMGNGTNATH AAYGGNCARGCNGTNTTYMGNAARTCNAAYTGYGAYGTNMGNCCNATGACNGTNTTYCAY CCN---------TCNGAYGARGARGARCCNYTNATHGARGARGARCARGARACNATGCAR GAYGTNYTNTGYGARGARAARYTNCARCCNGCNGCNAARAARMGN------GCNAGYCCN CCNYTNAAYTCNACNGAYGAYMGNGCNYTNMGNACNMGNAAYMGNGTNMGNAARAARYTN CARCARMGNMGNGTNAAYGGNAAYGAYAAYTAYTAYCCNCCNCCNMGNTTYCARGGNGGN MGNMGNATHMGNAAYGGNGTNAAYGGNGAYGGNGGNATGCAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGARCAYCAY GARYTNGTNCARGARATGGTNACNATHGARMGNYTNCCNACNCARGARMGNYTNAARCAY GCNMGNAARMGNMGNATHCARCARYTNAARAARTGGAAYCARTAYGAYAARCARTTYGAR AARGARACNAGYAARAARAARAARAARGCNGCNMGNAAYGAYYTNGARGARGTNMGNAAR YTNYTNAGYGAYGAYGTNAGYCCNGAYGTNACNAAYGARGAYGGNYTNACNGCNYTNCAY CARTGYTGYATHGAYGAYAAYGARGARATGYTNTCNYTNYTNYTNGARTTYGGNGCNAAY ------------------------------------------------------------ ---------------------------------------TCNGARGTNAAYYTNACNAGY TCNTCNGGNYTNCCNCAYAARMGNYTNTTY---YTNAAYGAYACNAARGAYTCNGTNGAY TCNGAYACNAARYTNTCNGCNACNATGGAYACNGARGAYATHMGNYTNMGNAAYACNATH AGYGTNGAYCCNGARAGYACNAARGAYTCNGGNGCNTCNGAYTCNGTNACNGARGGNCCN ACNCCNACNAARAARATGAARMGNGGNTGYMGNGARGGN---------YTNGTNTTYGAR GARCCNAARAARGTNACNGCNGARAAYYTNTTYGARTAYCARTGGCCNCARGAYGARGGN GARTGGCAYATHYTNCARGARCAYATHAGYGAYTTYYTNAARATHAARTCNTTYAARMGN AARTAYCCNGAYYTNTAYMGNMGNGTNTGYGAYAARGARGARAARGAYTTYYTNMGNGAR AARGGNGTNGTNACNGARACNCARTCNGAYYTNGGNYTNACNGCNYTNMGNAGYGARGAR GTNTAYGAYYTNATGATGAARGAYTAYAAYGAYAARTAYCARGARTAYGTNGCNGTNYTN CARGARAARCARAARACNGTNATGAARGARAARCAYAARGARTAYGTNGTNGCNAARYTN GAYAARTCNAARATGGARGCNTAYTGYMGNAARGCNGCNMGNAGYGCNGCNGAYTTYAAY GCNAAYYTNATGMGNGARAARMGNGARGARMGNCARGCNTAYTTYGAYYTNCARACNTTY ACNATHCARCAYGCNAARAARMGNTAYMGNAARYTNCCNGCNAAYCARACNAARGTNGGN TCNTAYCCNGTNTCNGTNATHCAYGGNCARTAYCARGAYAARATHMGNTGGTTYGAYCCN GARGARYTNMGNAARATGCCNGTNAARACNGTNYTNGTNGAYCCNCCNGTNATGGTNAAR TAYCCNACNAARATHCAYGGNYTNGARAARTGYMGNATHTGYAARCARMGNGCNTCNAAR GARGARMGNATGMGNGAYATGYTNGTNMGNTGYGCNYTNTGYCAYAARGTNGGNCAYATG AGYTGYYTNGAYYTNACNGARGARYTNGTNGCNGTNATHAARACNTAYCCNTGGCARTGY ATGGARTGYAARACNTGYGTNCARTGYATGGAYCCNTAYGAYGARGAYAARATGATGTTY TGYGAYYTNTGYGAYMGNGGNTAYCAYACNTTYTGYATHGGNYTNAAYGCNYTNCCNACN GGNCAYTGGGARTGYMGNAGYTGYTCNCCNGARTGYYTNATHATHTCNMGNGTNYTNGTN GGNYTNCAYTCNGGNTGGACNYTNGCNGTNTGYCCNATGTAYYTNGCNGARATHTCNCCN NNNAARATHMGNGGNNNNATHGGNACNTGYCAYCARYTNGCNATHACNATHGGNATHYTN TTYTCNCARATHYTNGGNYTNCCNNNNYTNYTNGGNACNGARGAYYTNTGGCCNYTNYTN TTYGCNTTYAAYNNNNNNCCNNNNYTNATHTGY--------------------------- ---------CAYGAYGTNMGNTTYGCNTCNGCNGAYGARGTNAARGARGGNTCNTGGTCN TCNAARACNAARYTNTTYTGYYTNGGNGGNGGNTAYGAYYTNGGNTAYATHGARTCNYTN GGNAARACNGGNATGMGNATHATHMGNGARTTYGTNAAYGAYGGNGGNTCNTTYYTNGGN ATHTGYGCNGGNGCNTAYTTYGCNTGYGAYTTYATHGTNTTYGAYAARGAYGGNCCNYTN GARGTNGTNGGNGARMGNAGYYTNAARTTYTAYCAYGGNAARTGYATHGGNCCNGCNTAY GGNGGNTTYGAYTAYAAYTCNMGNAARGGNGTNGTNGCNGCNCCNATHACNTAYAARAAY ATGAARATGAARACNTAYTTYGARGGNGGNGGNTTYTTYYTNCCNTAYGAYGCNACNTCN CARAAYGARACNATH---GTNYTNGGNTGYTAYGARAGYYTNAARAAYACNCCNGCNGCN ATHGTNAARTGYAGYTGYGGNAARGGNACNGCNYTNYTNTCNGGNGTNCAYATHGARTAY TCNTCNCAYTTYYTNAAYCCNGARGAYAARTAYYTNAARAARGTNYTNCCNCAYYTNATG CAYTAYGARTCNAGYMGNAAYTTYGTNTTYAARGAYATGYTNMGNCARYTNGAYGTNGTN TGYACNATGGCNAARMGNGGNCCNCARTCNGARYTNACNGAYMGNAAYTGGGAYGAYGAR GAYGARCCNGARGARTGYGGNGTNTTYAARCARGCNTCNTCNGAYACNATGCARCARMGN GTNATHAARAARGCNAARMGNMGNGGNGGNGGNGAYGAY------TCNTCNAARGCNTTY GGNGGNTTYGGNGGNTTY---------ATGAARACNTCNCARAAYAAYTCNGGNACNGCN ACNACNTTYAARCCNAGYGTNTCNTTYAAYTCNACNCARTCNGTNTTYGCNGGNGCNTCN TCN------TCNATGGARAAYTCNTCNACNTCNTCNAARAGYGARYTNAARGAYAAYTCN TCNTAYYTNCAYGCNYTNAARTCNYTNAAYGARAGYGTNYTNTCNTGGATHAARCARCAY GTNGARAARAAYCCNTAYATHATHYTNACNCCNATHTTYAARGAYTAYGARAARTAYCAY GARTCNYTNGARGCNAARAARTCNTCNAGYAGYATHTCNTCNAAYGGNAGYACNAARACN GARGCNAARTCNACNTTYGGNTCNGTNGCNTTYTCNAARCCNGARTCNAARGARACNAAR CCNAARGAYGAYAAYGCNAARGAYGCNGAYAARCCNTTYGGNTTYGGNCCNTCNCCNTCN AAYGGNAGYGGNTTYAARTTYTCNACNACNTCNATHAGYACNGCNTCNTCNGGNTTYACN TTYGGNTCNACNGCNTCNACNTCNTCNGGNTCNGGNTTYGGNTTYAAYTCNTCNACNACN ACNACNGCNAGYAGYGGNTTYTCNTTYGGNAGYAGYCCNYTNTCNTCNTCNACNACNGCN GCNACNGGNGCNAGYGGNTTYTCNTTYGGNAGYAGYTCNACNACNGCNACNCCNGCNACN ------------------GGNAGYGGNTTYTCNTTYGGNGCNYTNGCNGCNAARGCNATG ---TCNGARAAYACNCARAARTCNAAYACNGARAAYAARGAYGGNGAYGAYGAYGARTAY GTNCCNCCNAARCCNGARGTNAARGARATHCARGARGARGGNTCNYTNTTYTCNAARMGN TGYAARATGTTYTAYCARAAYGARGGNCARTGGAARGARMGNGGNGTNGGNAAYGTNCAY GTNAARCCNYTNGAYGGNAAYAARACNCARYTNYTNGTNMGNGCNGAYACNAAYYTNGGN AAYATHYTNYTNAAYATHAAYGTNACNGTNGCNYTNCCNGTNTCNMGNCARGGNAARAAY AAYGTNYTNYTNGTNTGYGTNCCNAAYCCNCCNYTN---AARGARGGNAARGAYAARGAR AGYGAYCCNAARCCNATHTCNATGYTNATHMGNGTNAARACNGGNGARGARGCNGAYGAR YTNYTNGCNAARYTNGARGARMGNAARGCNYTNYTN------------------------ ------------------------------------------------------------ ---------------------------GARAGYATGGGNGGNTAYGCNAAYCCNGTNCCN ACNMGNACNATHCAYCCNMGNGGNGTNAARCCNGARGCNCARGARAAYGCNGCNGGNAAY ACNGGNGGNAAYATGAARAAYYTNATHGARAAYTAYGGNAAYYTNTCNGTNGCNCCNAAR CCNGARCCNAARGTNAARGGNTTYGARGCNCARGARTAYAARGARMGNGARCARGGNAGY ACNAARYTNYTNYTNGAYCAYTAYAGYMGNGAYCCNATHCCNGTNTCNGARCARCCNCCN CCNCCNMGNYTNGGNYTNGGNGCNGGNGARATHGCNGAYAARCAYAARGGNGARCARATG GGNCCNYTNATGMGNYTNGARGGNAARAARACNCARMGNTCNCCNMGNCARGGNCCNYTN CAYCARACNTCNCARGGNGCNAGYTGGGAYGARACNCCNCCNCARAAYMGNTGYMGNCCN GARGGNGARAGYATHGCNTCNAARAAYAGYGCNGAYTCNATGGGNGARATHYTNYTNCAR AAYAAYGTNYTNYTNCCNCARMGNAARGARACNAARGTNYTNAARCAYYTNCARCARTCN GAYATGTCNMGNAARATHCCNCCNCAYMGNGTNYTNGGNGARGGNGTNCARAAYTTYGAR AARGCNCAYAAYMGNGARGAYATGAAYGCNATHATGCAYGGNAGYCCNTCNGCNGGNGAY ---MGNCCNMGNAGYGGNAARMGNTCNATGCCNCAYYTNCARAARAGYGARYTNTGG--- ---------------------------------ATHGCNGARTTYTAYGGNGCNACNGAR GGNGTNACNATGYTNYTNAAYATHAAYAAYAARCCNGGNGCNATHGGNMGNYTNTCNCCN YTNATGAGYYTNGAYCCNGAYCCNAARGTNYTNGTNAARTTYGAYTAYGGNACNGCNYTN CCNATHMGNGAYAARCAYGGNMGNTGYATHAARGTNAARGTNGAYGARCCNGGNYTNYTN YTNAGYAARGTNCCNGAYAGYATGATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TCNTAYTGGGTNTTYGGNCAYTCNTAYACNTGYGAYTGGTCNGTN GTNTGGACNGCNMGNGGNGCNGTNATHACNTCNTGGATHATHTGYATHATGYTNATHATH ATHGCNACNATHTTYGAYCCNYTNGGNTCNATGGAYGAYMGNAAYGCNGTNCAYYTNAGY YTNAGYCARMGNGGNGARGARAGYATHGTNATHGGNAAYGTNTCNTCNGAYAARGTNTGG GARGTNMGNTGYMGNYTNYTNTGYTGYTGYATHCCNAARGAYTGGATGACNATHTCNAAY ATGGCNCAYTAYATGAARTAYGCNATGGGNAGYTAYGGNTGGCCNTTYTAYATHTAYGAY AAYYTNATGACNGGNYTNTGYMGNYTNTGYATHCAYTGYMGNTGYTTYTCNTGYTTYMGN GGNAGYAAYMGNGTNTTYGARGAYAAYTGYTGYCARTGYAAYACNGCNGCNATHAARAAR YTNTCNAARGCNAARAAYCAYGAYYTNGTNCAYGTNACNTTYCAYAAYAARTTYAARGAR ATHCCNTTYTAYATHGCNGTNGAYAARAARAARAAYACNGTNGTNATHGGNATHMGNGGN ACNYTNTCNYTNMGNGAYGCNYTNGCNGAYATHTCNGCNGARGGNGCNAARGTNGAYATH CCNGGNGCNGAYGARGGNTAYTGYCAYGARGCNATGYTNGAYTGYGCNCARTAYATHAAR CARCARATHGAYCAYYTNMGNYTNYTNGAYGARGCNTTYTCNYTNYTNCARCCNGAYGCN GGNYTNGTNGTNACNGGNCAYAGYYTNGGNGCNGGNGTNGCNTCNATHYTNTCNGTNYTN YTNAARCCNGAYCAYCCNCARYTNTGGTGYTTYGCNTAYTCNCCNCCNGGNGGNYTNATG AGYCCNTCNGTNAGYMGNTAYACNCARGAYTTYATHTGYTCNGTNGTNGTNGGNAARGAY YTNGTNCCNMGNYTNGGNATGTAYACNYTNYTNGAYYTNAARGTNAARATHYTNMGNGCN YTNTGYYTNTGYAAYAARCCNAARTAYCARATHYTNGCNTCNGGNTGYTTYMGNYTNYTN TGYTGYAARGGNTCNTCNGTNMGNAAYTCNAGYAAYGARYTNYTNGTN------CCNCAY TTYGARCARGARCARTGYAGYGTNYTN---GAYGARCCNATHCARGARTCNYTNAARAAR GCNGARGCNAARATGGARGARATHYTNCAYACNGAYTGGCCNYTNCAYCCNGCNGGNCAR ATHYTNCAYATHATGGAY------------------------------------------ ------------------------------------------------------------ ------------------------CCNTCNCCNTTYTCNCCNATGGCNCCNTAYGAYGAY ATGAAYACNCCNGARYTNAARAARGCNGTNTCNAARATHGGNGTNMGNCCNATGGGNAAR AARGGNATGAARCARYTNYTNAARCAYGTNTAYCARGARACNCAYAARTAYGARACNGAY ACNGAYGGNGARAGYACNCCNGTNAARMGNGTNAARGARAARACNTCNCAYACNTCNATH CAYCARYTNAGYAARAARTCNYTNTTYAAYMGNAAYAAYGAYGTNGARTAYGGNAGYTCN TGYTCNACNGARGARTCNMGNGARACNGAYTTYMGNTCNAARATHMGN------------ ---------------------------------GCNTAYCARGAYGGNATHAAYGGNGAR CAYGTNMGNCCNGCNCCNTCNYTNCCNAAYTGYYTNCCNGARGAY--------------- ------------------------------------------------------------ ------------CAYGARGARGAYGAYYTNATHGGNTCNCARGAYTCNAGYAGYAGYGAR GGNCCNGAYYTNCCNGARGARAGYATHYTNCARATGTGGCCNGARGARGAR------GAR ACNGAYYTNACNCARYTNACNCARACNAGYGCNGARGCNYTNACNGCNAARYTNATGAAY TTYYTNAARGAYAAYCCNAGYATHTAYGARAARATHYTNATGTAYGARGCNYTNGARYTN GAYGTNYTNAARAARCARATHTCNGARGCNGGNATHMGNATHGGNYTNGCNAARYTNCAR GAYTTYYTNGAYGARMGNTGYATHACNTTYTCNATGAARAAYATGAGYAAYMGNAAYAAY MGNCARCCNCARAARAARACNACNGGNAARTCNCCNMGNAARACNAARCCNAAYAGY--- ---TCNGTNYTNGARCARTCNATHAGYTGYATGMGNACNAARATGAAYAGYTGGATGGAY AGYATGAARGARAARATHATGGARGARATGATHAARCARYTNGCNATGACNGTNCARGCN CARCARAAYGARAAYAARAARTCNAAYAARMGNYTNYTNGCNGAYAARAGYTGYYTNGAR AARCARGTNAAYACNYTNACNGARAARATHAAYGARYTNGARTGYGCNYTNGGNCARAAR AARACNYTNGTNAARAAYATGACNGAYTCNATHTGYTCNCARAARAARAARTTYGARCAR GCNAARTGYTTYTAYACNTGGAARACNGARTGYGCNGAYAARGAYMGNGARTGYTTYACN GAYMGNYTNGCNTGYGAYCAYCAYAGYMGNAARYTNGCNYTNMGNAGYYTNAARGCNTGG TAYGGNYTNATHCARTGYAARTGGMGNAAYMGNGTNGARCAYGARTGYCARAGYCARGCN AARAGYGTNTGYATGAAYYTNAGYAGYGAYTAYGARGTNAARGTNTGYATGYTNAAYGAR AARATHAARTCNYTNGARGARAARGTNTGYYTNYTNCARCARGARMGNGARATGTAYTCN GARCARGTNAARAARGCNTTYATGMGNGGNATGTGYGCNYTNAAYGTNGARACNATGTCN GTNYTNGCN---GARGARAAYCCNCARCARCARGARACNTCNTCNGCNMGNCCNAARTCN ---------AGYATHCCNGGNTAYTCNGTNGARGARGARGTNYTNAAYTCNATGACNTAY TCNAGYATHCCNCCNAGYAGYTCNAARAAYCARGCNCCNAARAGYTTYCCNACNTTYTCN TCNTCNGTNCCNGGNCARACNATGACNGGNACNATGGAYACNCARATHCARACNTCNGAY ACNATGYTNTCNACNMGNAARCARAGYGARAARAARGGNAARGCNGGNAARGGNAARGGN AARGGNGGNAARAAYAARACNGGNAAYGCNTCN--------------------------- ------------------GTNGCNYTNGCNCCNCCNATGGCNTCNGTNGTNGTNGARMGN CAYCARTCNATHAAYAARCARACNYTNGGNAARGCNACNGCNGTNMGNTAYCCNAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY GAYGAYGAYTTYCCNATHTCNCCNMGNACNGAYGARAAYTAYMGNAARATHGAYGCNGAR TTYGCNMGNGCNATGAAYGAYGGNGGNYTNAARTCN---TCNGTNCARTAYCARGTNCCN GTNCARCCNCARGCNGCNCARTAYACNGCNGCNCCNGCNAGYATGTCNAGYGGNGGNTCN GTNATHGTNATHCARTCNTCNGGNGCNATHGGNAAYCARGCNAAYMGNCCN--------- ---------------CARGCNGTNGCNTCNYTNYTNTCNAGYGGNCARYTNAGYAGYACN AGYGCNGTNCCNCARGCNCAYCCNGTNGCNATHCAYACNGCNGGNGARATHCAR---GCN YTNAAYAAYGCNTCNACNTCNGCNCCNCARACN---------GCNGCNAGYAARAARCCN GGNYTNAARGTNGTNATHCCNGAYMGNGGNCCNCCNGTNTCNCARACNAARGTNCAR--- AAYTCNTCNYTNGAYACNCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGAGYTCN GAYACNTGYTAYAARTGYGGNGGNMGNGGNCAYTTYGCNMGNGAYTGYMGNAAYGGNGGN GAYTCNCARMGNTCNTTYMGNCCNGGNCCNGGNGGN---------------------TTY TCNGGNGGNCARAARTGYTAYAARTGYAGYMGNGTNGGNCAYTTYGCNMGNGARTGYACN CARGAYCARGARMGNTGYTAYAARTGYAAYGGNTTYGGNCAYATHGCNAARGAYTGYGAY AARTCNATH---ACNACNGGNGCNTGYTAYAAYTGYGGNAGYGCNGAYCAYYTNCARMGN GAYTGYCCNCARGCNATHGTNAARTCNTGYTAYMGNTGYGGNGARTCNGGNCAYYTNGCN AARGARTGYCCNGCNGAYATHCCN------------AAYAARCCNTTYGCNGAYGAYMGN AARTGYTAYACNTGYGGNGGNGTNGGNCAYYTNGCNAARGAYTGYCCN------------ TCNCCNMGNMGNGARTGYTAYMGNTGYAAYCARACNGGNCAYGTNCARAARGAYTGYCCN AAYTCNCCNATGTCNAAYACNACNTGYTAYAAYTGYAAYGARACNGGNCAYATGGCNMGN GAYTGYACNGCNGARTAYCARMGNGCNGCNGTNGCNGARAARAAYGAYGCNYTNAARGAR ACNAARAAYTAYACNACNCAYTCNYTNGCNAGYGTNGCNTAYCARATHAAYAGYYTNGCN ACNAAYTTYYTNAARYTNYTNGAYYTNCARCARAGYCARYTNACNGAYATGGARTCNAGY GTNAAYCAYYTNAAYCARATHGTNATGATHCAYAARGARAARGTNGCNMGNMGNGARATH GGNGTNYTNACNTCNGGNMGNAGYGTNCCNMGNCCNCCNGGNATGAARAAYGGNATHATH TAYCCNGARCARACNGARMGNCCNATHAARTAYACNMGNAARCARATHGAYTAYACNATH YTNGAYGAYATHGGNCAYGGNGTNMGNTCNCARCARCARCARGCNACNACNCCNMGNTCN GTNMGNTCNCCNTCNGTNAGYAGYACNCAYAGYAAYATGAGYGCNAAYCAYCARCARGCN CCNACNTCNAARCCNCCNACNCCNCCNGTNGGNACNGGNGCNGGNAGYAGYACNATHGGN MGNGCNGCNGGNAGYCAYTAYMGNTCNYTNGGNCCNCCNGTNGCNCCNCCNGTNGCNCCN GGNGTNCCNTCNCCNGCNACNAAYCCNCCNCAYTTYCARCAR------GCNTCNCCNCCN YTNCCNCCNCCNCCNATGTCNGAYGGNCCNGTNCARTTYGAYTAYGGNGCNCCNCCNCCN CCNCCNGAYTTYAGYGAYCARMGNGARGGNCCNCCNAGYATGMGNGAYGGNGTNCCNCAR CCNYTNGARAAYGAYATHTAYGGNACNGCNCARGGNGTNGGNGAYGAYCCNTAYGCNGCN ACNGGNCCNCARTTYYTNGCNCARACNGCNTGGATHCCNAARCAYTAYYTNGARAARGTN YTNGCNATHTAYGAYTAYCARGCNAAYAARGCNGAYGARYTNTCNTTYGCNGARAAYGCN ATHATHTAYGTNATHCAYAARAAYGAYGAYGGNTGGTGGGARGGNGTNATGGAYGGNAAR ACNGGNYTNTTYCCNTAYAAYTAYGTNGARCCNTGY------MGNTAYYTNATHATHACN GCNGAYGAYTTYGGNTTYAGYAARGARMGNAAYCARGGNGTNGCNGARGTNYTNAARAAR TCNGCNGGNAARAGYGTNTCNYTNYTNYTNAAYTGYACNGGNACNGARGAYGCNGTNYTN TTYATHAARMGNAAYGCNTGYTGYGCNGGNYTNCAYYTNAAYYTNACNGARGGNCCNTCN YTNTGYAARACNAARCAYACNACNYTNACNGAYGAYGCNTCNAARTTYTGGGGNAARTTY GARYTNMGNAARYTNYTNGAYCARGGNAGYATHTGYCARCARGARATHMGNTAYGARATH YTNAGYCARATHGARGARTTYACNMGNYTNGTNGGNMGNMGNCCNGCNTAYGTNGAYGGN CAYCARCAYATHCAYGTNCAYCCNGCNGTNTCNAARATHTTYGCNTCNACNYTNCAYGCN TAYAAYATHCARGCNACNMGNTTYCCNGTNGARATGTCNYTNGARACNAARACNGGNATH CAYCCNAARTCNYTNGARTTYTAYAAYAARGTNATGGARGAYGCNCARTCNTGYAARTCN ACNTTYGAYTCNAAYGGNATHMGNACNACNGAYACNTTYGTNGGNYTNTCNACNATGGGN GCNAAYATGACNGTNGGNMGNYTNCARTCNGCNYTNYTNGARGCNTTYGARGARGCNGAR AAYMGN------TGYGAYACNTCNAARCCNTTYACNTGYGARYTNATGACNCAYCCNGGN TAYGTNACNGGNAARTAYMGNGGNGGNTTYGAYTGGYTNTCNGAYGAYTTYGGNTGYTCN AAYGARMGNGARCAYGARATHAARGTNYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNCARACNTTYGAYACNTAYAARCAYTTYCAR GAYGCNYTNACNGAYTAYTGYAARMGNACNCAYACNYTNTTYGTNAARGAYAAYGCNAAY AARACNYTNATHCCNAAYGARGAYTAYCCN---------TAYGAYAAYGTNMGNTAYGTN TGYAARCARGGNGGNMGNATGMGNAARTCNACNAGYAARGGNATHMGNCAYAAYYTNACN ACNTAYAARATHGGNTGYCCNGTNGGNATGAARGTNMGNYTNAARAARTGYAARGGNCAR AAYATGTAYCARYTNTCNMGNGTNGTNYTNGARCAY---AAYCAYCCNGTNTCNGARGAR GTNYTNAARACNTAYCCNGARATGMGNMGN------------------------------ ------------------------------------------------------------ ------------------------------------------YTNACNGTNGTNGCNMGN MGNYTNMGNCCNTTYGCN---YTNGGNYTNYTNAAYAARTCNGGNAARAAYATHCAYACN ACNCCNAARAARTGYGGNGARGCNYTNTAYMGNGARAARATG------TTYGARTAYCAR GARCCNAARTAYATGCARCAYGCNGGNACNGCNTTYAGYGCNTTYATGTGGTAYTGGATH YTNTAYCAYTGYTAYTTYGARTTYGARCAYYTNGTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GTNGGNACNGCNACN CAYATHTTYAAYGCNACNTTYGARACNTAYCCNGGNMGNATGGTNACNMGNACNGTNGAY GGNGCNATHGGNATHGCNGARAAYYTNGTNGAYAARTAYYTNCCNGARGARGARAAYAAR GAYTCNGARAAYGARATGTCNGAYTCNAGYAGYAAYTCNAGY------------------ AGYAGYGGNAGYAGYGTNGARCARATGGARAARATGGAYCCNTCNCCNAARMGNGTNYTN GTNCAYGCNAGYTGYGTNACNGARAARTTYMGNMGNMGNATGTAYCARAARGCNATGAAR GAYYTNACNTAYGCNMGNTCNMGNACNGTNTCNGCNYTNAAYMGNATGAAYAARACNGTN GAYYTNGTNGAYTAYGCNAARTCNAAYGTNACNATHGCNAARGARAARGTNAAYCAYATG TGGGARATHATHACNGARAAYGGNGAR------------------GARGARAARACNGTN TTYAAYGGNACNATHGARGAYMGNATHGTNGCNYTNGGNCARYTNGTNGCNMGNCARGTN AARACNGGNATHGARGARTTYGAYMGNGCNTGYGCNGARATHGGNAARATHMGNGARGAY CCNATHTCNAARTCNAARGARTAYAARGARYTNATHGCNACNTTYYTNTCNGTNGAYTCN YTNAARAAYTTYACNTCNCARAGYATHTCNAARGCNAARGARTCNGTNMGNYTNATHCAR GAYMGNGTNCAYAGYTTYATHAARATHTAYCCNAGYYTNTCNTGGGTNGCNGTNGAYATH GAYATGGARAAYYTNCCNYTNAGYGARTCNGAYYTNYTNGARAARATHGGNYTNACNGAR MGNCARGTNTTYTCNYTNAARCARTCNTGGAARGGNATHAARMGNAARATGGARGARACN GGNGTNGARATGTTYATHMGNYTNTTYCARACNAAYAARGARYTNCARACNATGTTYCAR GGNTTYMGNAAYYTNTCNTCNTAYGAYGARYTNMGNTCNAAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGN---GGN AARTAYTGYACNAAYAAYTCNGARTGYCARAARGGNGARTGYTGYCARATHCARAGYGAY TTYATGATHGTNAGYAARMGNGCNTCNATHYTNCCNYTNCCNCARGTNAAYGGNAARAAR AARAARACNGGNACNTGYGARCCNTAYMGNYTNGARGGNGARAGYTGYAGYMGNYTNGCN AARATGAAYGGNAAYTGYAGYTGYGARCCNGGNACNCAYTGYAARGGNGARCARGTNCCN TAYAARCCNGAYGCNAGYYTNGCNAARMGNAARATGGCNMGNCCNATGCCNGGNCAYGTN TGGAGYTTYACNTGYAARAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TGGYTNATGTCNACNGCNACNTGYCCNGTNCAYTTYAARTGGGAR GAYYTNGGNATGATGTAYTGGCCNMGNTGGATHAARAARGGNACNTGYGGNGAYTAYAGY AAYCCNATHCARGAYGCNTTYCARAARTCNGGNCCNAAYTCN------------------ ---AARCCNACNTAYTGYTCNTGGCCNCCNGGNATGMGNTGYGTNCCNTCNAARGARAAR AARATHAARYTNYTNMGNTGGAGYTGYAAR------------------------------ TCNCCNCCNYTNGTNATHYTNATGGTNTGYYTNCARGGNGTN---TGYGCNAAYGAYAGY ACNGTNCCNGTNATHGTNTCNTCNGGNGTNGCNTTYGTNYTNYTNATHATHGTNGTNTTY GCNGTNTGYTAYTCNGARTCN---------TGGGTNAARTCNATHATGAARMGNGARGGN AARGTNAARATGCCNAARTCNTAYTTYMGNAARAARMGNYTNTCNAARAARMGNCARATG CARAARACNCARGTNATHGCNAARTCNGTNGTNTCNAAYGGNGGNCCNGTNCCNGTNCCN GTNCCNGTNCCNGTNATGAAYAAR---GARAARATGGTNCARGGNTGGAAYCARCAR--- ---------ACNGARGCNTAYGARGARAARGCNATHAGYATGGARYTNGGNGARGARYTN GAYGARGARTTYCARATHGARACNTCNATHGTNGAYAAYGARGTNYTNGAYGTNGGNCCN TTYAARAAYYTN---GARTCNGGNAAYGCNAARCCNGTNGAYGGNAAYGTNTAYAAYAAY CCNTAYATHTTYAGYAAYAAYGAYMGN--------------------------------- ---ATGGCNAARYTNYTNYTNAARGAYGAYGCNYTNAAYYTNATHTCNAAYGTNGAYAAY TTYYTNTTYGAYTGYGAYGGNGTNYTNTGGGAYGGNAARGGNCCNATHGARGGNAGYYTN GAYACNATHYTNAARYTNAARCARYTNGGNAARAARGTNTAYTAYGTNACNAAYAAYAGY TCNMGNACNMGNCARGAYTGYGTNGAYAARTGYCAYTCNYTNGGNTTYCCNGCNGARGTN GAYGAYATHATGTGYACNGCNTAYATGGCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGAAYMGNAAYMGNCARMGN GAYMGNAAYATGAAYMGNGAYAAYMGNTCNGCNMGNAGYGGNGAYGGNYTNYTNGGNGAR AGYCCNYTNGGNGGNGGNGGNGGNATGGGNAAYCCNYTNGGNGTNAAYCCNYTNGGNGCN AAYCARYTNGCNYTNGCNCARTCNYTNYTNCARCARCARCARCARCARGTNAAYGCNGGN TTYGGNGGNGGN------GAYTTYGGNGGNGCNGGNGGNTTYCCNGGNGGNATGCARGGN ATGCARYTNYTNCARCARCAR---------------------CARCARATGMGNCCNCCN CAYGGNYTNGTNGGNGGNATGCAYAAYGAYMGNAARMGNAGYGGNGGNCAYATGMGNMGN GAYCAYGAYGARAARMGNGGNMGNMGNGAYTCNTGGGGNMGN------------------ GGNGARMGNGAYMGNTCNCAYGGNAAYCARAAYMGNAGYGGNCARGAYAARGARMGNMGN GAYTCNGCNAARGAY---MGNAARAARGGNGARGAYTAYGAYCCNGCNGARCCNACNGAR GAYGAYGAY---------------GARAARAAY---AGYAAYYTNTAYTGYCAYGTNTGY GGNGTNTCNGTNTAYGAYGARGARAGYYTNAARMGNCAYYTNAAYGGNYTNAARCAYAAR GCNMGNATGGARAGYATHGCNAAYGTNCAYGCNATGMGNGCNCCNCARATHAAYCCNMGN ATGAARGCNGARGARCAYYTNMGNAAYATHGARMGNAARGGNGGNMGNGAYCCNGAYTTY TTYTGYAARATHTGYAAYAAYGAYYTNACNATHCCNTGGGARAARCAYMGNTAYTCNAAY ATHCAYAARCARMGNCAYYTNCARGTNMGNAARGGNTGYGGNTGGTGYAARGTNCAYAAY TTYAAYAAYTTYACNGARGTNYTNGAYCAYMGNGARACNGARGARCAYAARAARAAYGCN YTNCARTAYGGNAARAARGAYGARGARAARGAYGGNTCNMGNAARMGNYTNAARGAYGGN AAR---------------------------------------------------GARGGN GARGAYGAYGARAARYTNGARGARGARGARGARGAYYTNACNATHCCNGARTAYGAYCCN GARGTNCCNGTNGGNYTNGAYTAYGTNATHCCNGTNACNGGNTAYTTYTGYAARYTNTGY CAYAARTTYTAYAAYAARAARTCNGCNMGNGCNGCNCAYTGYYTNAGYGARGCNCAYTAY GCNAARTTYAARGAYGCNACNGARATHAARATHGCNGCNAARYTNAARMGNGARGARGAR GCNMGNYTNCARAARGARYTNGARGARGCNGARGCNAAYGARGCNMGNGARAAYGGNGAY GAYCARAAYGAYGAYAAYGARGAYGAYGARAAYATGGARGARCAYCARGARGGNGARGAR GCNGARGCNGARGARGARAARGARCARGARCARGARGARGARGCNGARGARGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNGAYTTYTGGAAYTAYATHCARCARACNATHGCNTAYGAYCCNACNACNCAYGAYYTN AARCARATHTGGACNAGYAARATGCCNYTNCARGGNGCNYTNYTNACNTAYMGNGARCAY YTNYTNTGYYTNGGNGAYAARATGCAYAARATGGGNGTNGAYMGNACNGARGCNGCNYTN YTNTGYGCNATHAGYATGACNAGYATHGAYTGYCCNGGNYTNYTNAARGTNAAYACNGTN ACNGARGTNCARACNGTNYTNATHGAYGCNYTNGARGCNCAYYTNGTNAARTCNCARTCN CARGGNMGNYTNCARACNYTNYTNGGNYTNATGCCNCARGTNMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATHCAYGAYATH AGYATHGCNATGGCNAARYTNATHCCNGTNYTNAGYTCNYTNYTNCCNAARATHTGYGGN GAYGCNCCNAAYGCNTTYATHCARGARYTNYTNYTNATGGARGARYTNAARCARYTNGCN GCNAAYGTNTAYGARGCNTTYAGYCARGAYACNAGYAAYGGNCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GCNACNGGNYTN AAYATGGARGAYCCNGTNTTYMGNGCNTTYATHGGNTAYGCNACNGTNGTNATHGCNAAR ACNYTNYTNATGAGYTTYYTNACNGCNMGNCARMGNATGTCNAARAARGTNTTYCCNGTN GARGARGAYYTNAARTAYTTY------------AARAAYAARGGNTCNACNGCNAAYGAY ---CCNGAYGTNGARMGNGTNMGNMGNGCNCAYCARAAYGAYYTNGARAAYATHATHCCN TTYGTNYTNYTNGGNYTNYTNTAYACNGTNACNGGNCCNGCNYTNGCNACNGCNYTNATH CAYTTYMGNACNTTYGCNGCNGCNMGNATHYTNCAYACNYTNGTNTAYYTNGGNAARATH CCNCARCCNGCNMGNGGNATHACNTTYTTYGTNGGNCARGTNGTNAAYYTNTCNYTNGTN TTYCARATHYTNAARCARGCNGCNTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GGNGTNCAYATHGTNCARAARYTNMGNCCNGTNGARCARYTNAAR GCNYTNYTNYTNGARTGYGGNGGNCCNGAYGCNGARCARGTNAARGCNTTYTTYMGNYTN CAYAARYTNGAYCARGCNTGYGCNGTNTGYYTNGTNYTNGCNTGYTCNMGNGCNGCNGCN GAYCARCARGTNTCNGAYTGGGCNMGNATGGCNTTYTTYATGTAYGGNGGNGARGCNYTN TGYAAYYTNACNAGYTTYMGNCCNATHCCNGGNATHGGNAGYCCNTTYCCNAAYCCNGCN ATGTAYAGYCCNGGNAAYATG---ATHCCNAAYAAYCCNATH---CCNAGYATGACNTCN ACNCCNGCNCCNAAYACNATGTCNCCNATGGCNGCNATHGGNGGNGGNAAYMGNAAYCCN YTNCARGARATHATHTAYTCNGGNAARCAYAAYGGNATHTTYATHTTYYTNAGYMGNATH YTNMGNCCNTTYTGGGAYTGYCCNGTNACNACNGARTTYATHCAYGAYTCNAARGAYGGN AARTTYAGYTAYYTNACNTCNAAYTTYGGNACNGARGARYTNTGYACNGCNYTNGARATG GTNMGNGAYYTNTCNGAYTTYGTNGAYTTYAAYTCNAARTTYGAYGTNGAYTCNCAYATG GAYATHATGAAYACNGGNMGN---MGNATGGAYGGNAGYATHGAYGARCARAGYMGNAAR MGNATGCARATHGARGCNCARMGNATGGARAARATGTCNYTNCARCAYYTNCARGAYYTN YTNCAYMGNACNGARGARGTNYTNGGNYTNTGGMGNYTNYTNATHGAYCAYCARTTYCAY ATHYTNGCNGCNGCNATGGCNCARGAYATHCARAAYCARYTNMGNAAYATGACNYTNAAR ACNYTNATHACNAGYGGNAARGAYGTNTGYAGYACNYTNATHAAYTGYYTNATHACNMGN TAYYTNAAYGAYAAYGCNACNATHGAYGCNYTNAAYGAYMGNYTNMGNGARGTNTGYCCN ACNYTNTAYAGYACNGAYGAYGCNACNTGYTCNAARTCNAAYGARYTNYTNCARGCNGCN AARATHAAYCCNAAYATGYTNGAYAARGARMGNCARYTNCARGARGCNYTNCARYTNYTN AARAGYGTNTCNCARCCNYTNAAYYTNTCNGTNATHTGYTCNCARYTNGCNAGYGTNCAY TTYTAYYTNGGNATHGTNGARYTNGCNYTNAAYGARGCNAGYAARYTNGAYCCNCARGGN ATGGCNATHCAYTTYTAYAAYAGYGGNGARCCNCARGARGAYATHCARGGNATGCARGCN TAYATHGCNMGNATGGARTGYTAYAARTGYATHACNGAYACNYTNACNTAYYTNGGNTCN GCNAGYACNAAYCARGCNCARATHTCNAAYATHTCNTTYYTNGGNTCNTCNTCNAAYAGY CARGAYTCNAAYMGNYTNGAYACNCARCARGCNGARTGYTTYMGNGARGARATHTTYAAY ATHGCNYTNMGNTGYGARGAYTCNYTNTTYCAYGCNGCNYTNTAYGARTGGYTNTTYAAY ACNAAYCARGCNGARAARYTNYTNGARATHAGYACNCCNTTYGTNGARCARTAYYTNMGN MGNAARGTNAAYYTNCAYACNGARAAYACNAAYGCNYTNGAYYTNYTNTGGMGNTAYTAY GARAARGTNGARAAYTTYCCNGCNGCNACNMGNATHYTNACNCARYTNGCNGARMGNCAY GGNACNAGYGTNGAYYTNACNCARMGNYTNGARTAYYTNTCNMGNGCNGTNGTNTGYGCN AARAGYTCNACNTCNMGNYTNGGNACNTCNGCNGGNGGNGARACNYTNCAYGARYTNGAR GARAARATGGARGTNGCNMGNYTNCARATGCARATHTAYMGNTGYYTNTGYAAYATGACN AGYTCNCCNYTNGTNGARAAYGCNAARTCNMGNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNAARGAYTTYCAYATHCCNATHACNGTNGARCARGGNMGNGCNAARGTNMGNGARATG TTYYTNAARAAYAARCAYGTNTCNGAYATHMGNGTNATHGAYATGYTNGTNATHAARGGN CARATGGAYYTNGTNGARACNGCNAGYATHTGGAARCARAARCAYCAYATHATGACNTAY TTYAARGAYACNGTNAAYCCNAARCCNACNGAYTTYYTNAAYAARTTYTAYGARGGNCAR GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYGARATHGTNGGNATHATGCAYGCN AGYGAYAGYYTNTAYAARMGNATG---------------TAYAARGAYCARCARATGGAY CARGARYTNGARCAYMGNGTNAARAARGTNTCNGAYAARTAYTCNGARACNATHAAYATG ATHGCNAAYGARCCNTCNYTNGCNTTYTTYMGNATHCARGARCAYGTNMGNAARACNYTN CCNCARYTNGTNGAYACNAARCAYGARGTNGARGGNYTNCARTCNAARGTNCARGGNTCN TGYTTYGAYACNGAYTAYGCNATHAAYGCNGTNAARGCNATGCARAGYAGYTCNATHCAY TTYCARAAYATHCARGAYYTNATHAARAAYGCNATGTTYATGAARCARCARATHTCNTTY GARGARAAYAARMGNAARCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARATHYTNMGN CARGAYAARATGCARGARGAYTAYMGNAARACNTAYGCNATHGAYAAYGCNGTNGTNGCN AARYTNAARAAYGAYATHGARACNMGNGAYAARACNATHYTNGARYTNAARCARCARGTN AAYCARATGGARGCNGARATGAARCARGTNAARCAYMGNAAYAARCARYTNTGYGTNATH YTNGCNCARGGNGARATGAARGAYAARGCNCARGTNYTNYTNCARGTNGAYGARYTNAAY AAYGTNAARGAYGARYTNACNGARCARGTNACNTCNYTNACNGTNGARYTNGARAARGAR AARTCNAARAAYMGNGCNYTNAARTCNGARGCNGAYAARYTNAARGGNGGNAARCAYGGN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TAYTGYACNTTYYTNTCNGAYTAYATHMGNACN AARACNMGNGCNGAYGGNAARGARAAYAAYGARCCNACNGAYYTNGAYGARGAYGTNGAR CCNATHGAYGCNGAYACNATGAARGARCAYACNGARAAYAARMGNGARMGNGARGGNAAR TCNMGNAARAGYCARAAYCCNMGNMGNCAYCCNCARGTNAAYGARAARGAYTAYGAYGCN TTYGARATGGARGTNGARGARATHGAYGARACNGARAAYGGNAAYGARCARGAYMGNGCN GGNTAYGCNCCNGGNGCNGAYAAYCCNATGGAYYTNTAYAARAGYCCNCARATGCARYTN ATHCCNTCNYTNCARGAYGARGGNGCNGCNAGYTTYACNGCNACNACNACNCAYTTYGCN ACNCCNTCNACNMGNACNCCNACNACNMGNACNGGNACNAAYAAYAAYMGNTCNTCNAGY GCNTCNAGYYTNTAYTGGAGYTGYGGNTAYTGYGAYTTYCARAGYAGYAGYCARGCNGAR ATHAARGARCAYTCNAAYMGNACNCAYCCNGGNAARCCNCAYMGNTAYGTNGCNYTNATH AARAAYATGAAYCCNGAYTCNATHATHAAY---AARAAYGCNGAYAARAAYAARAGYAAY TCNCCNTCNACNCAYTCNMGNAAYAAYTCNCCNTAYACNAARACNGGNTCNTTYGCNTCN GTNAARYTNGAYAGYGTNGCNGGNAAYTTYGCNGGNGGNGAYGARGTNGARTCNYTNAAR AAYGAYGCNGAYGAYGGN---ATGYTNAARGTNAARTTYGCNGCNGCNAARCCNAARAAR GARACNACNACNTAYMGNTGYTAYCAYTGYAAYTAYACNGCNAARMGNCAYTCNTCNATG AARTCNCAYATHTAYTAYAARCAYMGNGGNAARGGNYTNYTNGCNGTNGAYGARGAYTCN TCNACNGGNCARCARGTNTTYTTYTGYGCNMGNGAYGAYTGYACNTTYAARTCNACNATH CCNACNGCNTAYYTNGCNCAYGTNGARCARTGYACNCCNTGGCAYAARCCNGARYTNGCN GAYGTNGARGTNGARCCNCAYATHMGNGARTGYYTNCARCARACNYTNACNTTYGCNGAR ATGGCNYTNGAYAAR--------------------------------------------- ------------------------------------------------------------ ---------------------------------------GGNGGNAARGAYAGYTGYTTY AAYATGATGACNTGYGTNGCNGARGGNCAYGAYGTNGTNGCNYTNGCNAAYYTNMGNCCN CAYAARGTNGAYGARYTNGAYAGYTAYATGTAYCARACNGTNGGNCAYCAYGCNATHGAY YTNTAYGCNGARGCNATGGAYYTNCCNYTNTAYGTNGCNACNATHAARGGNTCNAGYYTN TCNATHGGNMGNGAYTAYGTNCCNTGYGARGGNGAYGARGTNGARGAYYTNTAYCARYTN YTNTCNCARATHAARGCNGARMGNGGNATHGARGCNGTNAGYGTNGGNGCNATHATGTCN GAYTAYCARMGNGTNMGNGTNGARAAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNYTNYTNATHTCNACN GTNAGYATHGGNGARGAYGAYATHAARACNAGYAAYYTNGARGGNTCNTTYGARYTNCAR GAYGGNGAYGARYTNGTNGTNTAYATHAGYTAYCCNTCNYTNYTNAGYGARGARTTYACN GCNAAYGTNTTYGGNYTNTTYMGNYTNGARGGNAGYAARATGGCNYTNCARAAYCARGTN GARCARYTNMGNGCNCARYTNGCNCARGCNGARCARGARMGNCARMGNATGMGNGTNGAY YTNGAYGARTCNMGNYTNGAYACNGARATGAARGARMGNMGNMGNAARMGNAAYGCNGAR GARGARMGNAGYMGNGTNYTNGARCARGAYYTNYTNGARATGAARAGYCAYYTNGTNMGN TCNGTNGGNGCNATGTCNGARATGGARGAYYTNAARMGNMGNYTNGARAARAGYGARMGN CARMGNACNCARYTNTCNGAYCAYATHGARACNYTNGTNAARGAYYTNGARAAYMGNGAR MGNCARAGYGCNAARGTNATHAAYCARYTNAARGAYACNTCNGAYMGNTTYGARGAYACN GAYMGNCARMGNTCNYTNYTNTCNACNCARYTNGARGAYYTNCAYCARAARYTNAARGAY GTNTCNMGNGARYTNGARAARACNACNCAYGARYTNMGNAAYACNCARYTNTCNYTNTCN GARACNGARAARAARAARGAYGARTTYAARGGNMGNGCNCARGARACNGTNAARCARTGG AARGCNAARGTNAARCARYTNGARMGNGAYYTNGAYMGNCAYAARCAYGGNAAYGGNCAR ATGATGGCNMGNCAYGARCARYTNGTNAARGARATGGARGGNCARAARCARCAYGGNACN TAYAGYCARYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CCNTTYCARCAYGCNCARATHGGNTCNTTY TTYCARACNCARCCNGTNYTNMGNAAYCARTAYMGNGARGAYGCNTTYYTNMGNGGNTAY YTNCAYCARCAYGTNCCNAARGARCAYYTNTCNGGNATGGARTCNGAYYTNTCNMGNTTY GGNGAYMGNGTNTCNMGNGAYYTNTTYCARYTNTCNGTNCARATGGARGCNGARAARCCN MGNYTNGARCARTAYGAYGCNTGG------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG AGYGAYGARGAYMGNGARATHGAYATHGARAGYGAYGCNGAYGAYGARGAYGGNYTNGGN CARTTYGCNTCNYTNGAYGAYAARMGNGCNCAYCAYAAYGCNYTNGARMGNAARMGNMGN GAYCAYATHAARGAYAGYTTYCAYAGYYTNMGNGAYTGYGTNCCNCARGAYGAYAAYAAR ------AGYAAYGCNTCNAGYAARACNTCNMGNGCNCARATHYTNMGNCARGCNTCNGAR TAYATHATHMGNATGMGNGAYAARACNTCNCARAAYGAYMGNCAYATHCARATHYTNAAR CARCARAAYGAYGARYTNCARTCNCAR--------------------------------- ------------------------------------------------ATHAARGCNYTN CARAARTCNCAR---------GCNCCNGGNAARGGNCAYYTNAGYTAYYTNGGNGGNAAY ---GAYGAYTAYGAYGAYAGYGARGARGARCCNGTNGTNGCNTCNCCNCCNAARMGNAAR AAR--------------------------------------------------------- ------------------------------------YTNGTNGTNGGNYTNGGNAAYCAY CCNTTYCCNAARACNMGNCAYAGYGTNGGNATGATGGCNATHGAYAARYTNGCNCARTTY GAYYTNACNCARTGGGARAARYTNCCNGGNMGNAARGGNGGNTCNYTNMGNCARAARGAR YTNMGNGARGAYGGNAAYCCNGTNAGYAARGTNTTYYTNTTYAARCCNAARTCNYTNATG AAYATHTGYGGNTGYAAYGTNGCNAARACNGCNAARYTNYTNAAYGTNGAYGTNGAYCAY ATHTAYYTNATHCAYGAYGARYTNGAYYTNAGYYTNGGNAARGGNGGNATGAARTTYGGN GGNAGYGCNAAYGGNCAYMGNGGNGTNYTNTCNTGYATHTCNTCNYTNAARGCNGARGGN YTNTGGACNGAYGAYAARATH---------------------------------YTNMGN MGNYTNMGNATHGGNATHGGNMGNCCNCCNTCNAARTCNGGNGTNGTNTCNCAYGTNYTN GGNTCNTTYACNGARGAYGARAGYTTYTGYGTNAAYGCNGGNATHGARAARGGNYTNGAY YTNYTNATHATGGAYATHCARGARMGNGTNCCNCCNAAYAARCARYTNMGNATGCARAAR MGNATHCCNYTNATGAARGARMGNCAYCCNCCNGTNTTYAARTCNCCNCCNMGNAARTCN ACNGGNGTNCCNACNCCNCARTCNCCNCCNYTNGCNCCNMGNGTNACNTCNYTNGAYYTN GTNAARGAYGCNYTNAARGAYAARGAYYTNAARGAYGTNYTNGGNGARAGYGTNAARGCN GGNAARACNAARGGNGTNGARAAYYTNGAYAGYAARTGGAARAGYAARATGTCNGTNATG AAYGARGGNGTNCARACNAAYATGAARAARGGNATHGCNCARTCNTCNCCNGARGCNCCN GCNGARCAYGCNYTNAARTAYAARGCNGGNGTNGCNCCNCCNMGNCCNGCNAARAARTTY TCNGARTAYCARAARCARTTYCARTGGAARAAYGGNATGAARGCNTCNCCNYTNYTNGCN GCNGARCARATHGTNTAYTCNAGYAAYACNGARYTNGGNCCNTAYAARACNGARGCNATH CCNAARGTNTCNGARTAYMGNMGNGARTTYCARMGNTGGAARCCNGTNGARGCNAGYAGY AGYGTNAGYYTNAAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYAARTAYTTYGGNTAY GGNAGYAAYATGYTNACNGARMGNATHCAYATHAARAAYCCNACNGCNAARTAYATHAAY ATHGGNACNYTNAAYGAYTAYGTNTTYGGNTTYGARTCNCCNYTNAGYAAYTCNCARGGN TTY---GGNGCNATHGCNACNATHAARCCNTCNGTNGGNGAYAARGTNATHGGNTGYGTN TGGGARATHGAYGCNGAYCARATGATHCAYYTNGAYMGNCARGARGCNAAYTAYAARGCN ATHGARGTNGARGTNACNYTNGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARTCNGGN GCNAARCARTGGYTNCAYCCNTCNAAYGCNYTNACNAARGGNCAYATHYTNTAYACNGTN AARTTYYTNGGNGARTGYAARGTNGAYGARCCNAARGGNACNGARGTNGTNAARTCNGCN ATHACNAARATGAARTTYAAYAARCAYATHAARMGNGCNGARGGNCARAARCCNCCNAAR GTNGARYTNACNATHTCNGCNGAYGCNGTNAARATHYTNGAYCCNAARAAYAARYTNATH YTNCAYCARTAYCCNYTNCAYMGNATHTCNTAYTGYGCNGAYGAYAARTCNGAYAARMGN ATGTTYACNTTYATHGGNAARGCNGCNGAYAAYAAYGAYCAYTTYTGYTAYGTNTTYGAY AGYGARAARTGYGCNGARGARATHACNYTNACNATHGGNCARGCNTTYGARYTNGCNTAY AARMGNTTYATHGARGCNTCNACNCARGAYGCNGAYATHAARAARCARTTYYTNGTNYTN CARCARMGNGTNAAYAARYTNCARTTYGARAAYGAYACNYTNAARAARMGNYTNGCNGAY YTNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYGCNTCNCAYCARTCNGTNTCNCCNMGNGGNACNAARMGN ACNCAYGCNGARATHGARAGYGCNAGYGARAGYTCNAAYTCNCCNAARCCNTCNCCNCAR AARAAYAARAARMGNTGYTAYGTNTGYAGYTGYAARYTNGARYTNGCNCARMGNACNATH GGNAARTGYMGNTGYGAYCAYGTNTTYTGYCCNGCNCAYMGNYTNCCNGARYTNCAYGAY TGYGTNTTYAAYCAYAARGARGAYGGNMGNMGNGARGCNMGNGARAARATGGTNAARCCN ACNMGNCAYATGGGNACNTCNTTYMGNMGNGAYYTNTGYGARAARGARAARGAYGAYTAY GTNAAYGAYGCNATHCARAARGARGTNMGNTAYGGNMGNGGNCCNTAYTTYATHAAYGGN YTNCCNATHACNCCNGCNATHCARGGNTGYTGYAAYAARGAYCCNTGYTTYTGYMGNTCN GAYGTNATHTTYTAYGAYGGNATHGCNTAYGAYCARAARCCNTTYATHGARGGNGGNYTN MGNACNMGNCCNGGNAAYGTNATGTTYTAYGARGGNAARATGGCNGGNCCNTTYAAYCCN GGNAARTCNCCNYTNATHTAYGGNCCNAAYATHAAYMGNGAYAARCCNCCNCARMGNAAY TGYTTYGARACNGTNAARACNGGNCAYGGNTAYMGNCAYTGYTGYACNTCNTCNATHTAY GGNGAYACNGTNCCNCCNTAYCAYAAYACNCAYAARYTNGCNTAYACNAARYTNGGNYTN CCNCAYGGNAAYACNATHGGNTAYTTYMGNTTYAARCCNMGNMGNATHTGYTAYGAYMGN GARMGNCCNGTNCARMGNTAYGARGAYTGYTGYAAYTGYTAYCCNAAYGAYTAYGAYGCN AGYCARTAYATHAAYGAYGARTGYCCNGGNAARACNTGYTGYTCNGGNCARCAYAARCAR AARATHTTYATHAAYGTNACNYTNGARGGNYTNAARGTNATHGAYGCNYTNTCNATGATH GTNYTNCAYACNCAYCCNGTNCAYMGNATHTCNTTYATHTCNMGNGAYACNACNGAYAAY MGNGCNTTYGGNTAYATHATHGGNAGYGGNGAYGGNAARCAYACNTTYTTYGCNATHAAR ACNGCNGCNGCNGCNGARCARYTNGTNYTNACNYTNMGNGAYYTNTTYCARGTNGTNTAY GARATGAARAARAARCARGTNGAYGARGCNAARGARAARYTNGAYGCNAAR------GAR GAYACNGARGARGGNGARAAY------CCNTCNGGNGAYGGNYTNATHTCNGGNGARGGN CARACNCARACNCARCCNCCNGCNGAYGCNGAYGGNGTNTAYCAYGTNCCNCCNAAYAAY GCNCCNGTNAAYAGYATHGAR---GARCARCARGCNAAYYTNYTNGAYYTNGARGAYCAR GCNGAYTCNATHYTNAARGGNATHGARCARATHAARAAYYTNGARTTYGAYTCNTCNGAR GTNTCNTCNACNACNGCNYTNATHYTNGARAAYMGNCCNGARAAYYTNCCNACNAARGAY CCNGARGARGARGARMGNCAYMGNCARCARTAYATHCARATGATHGARGCNGCNAARAAR AARGARCARAARGAYYTNAARYTNAARAARMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGTCNGGNATHACNTGYYTNGCNTGYAAYGTNGGNTTYGAYGAY GCNGAYYTNGGNMGNATHCAYTAYAARACNGARTGGCAYMGNTAYAAYYTNAARMGNAAR GTNGCNGGNYTNGCNCCNATHACNYTNATGAARTTYGARGARMGNCARMGNGCNCARGAR ------GARTCN---GARTCNGCNCCNGCNCAYGARACNTGYYTNTGYAARCCNTGYAAY AARTCNTTYAAYACNTCNAAYGCNTAYGARAAYCAYYTNCARTCNAARAARCAYAARGAY GTNATHTCNGGNGCNGCNAARTCNAARMGNAARGGNAARAARAARTCNGGNAARTCNCAR GCNAGYGGNCARAARTAYGAYGARAAR---------------GARGARTGGATGTCNGAR GAYGAYGAYGAYTCNGAYGCNGGNTCNTGGGAYAGYTAYGARGARAAYATHYTNGGNYTN GARGARTGYYTNTTYTGYTCNCAYATHAGYCARTCNYTNGARGAYAAYYTNAGYCAYATG ACNGCNGAYCAYGGNTTYTTYATHCCNGAYGCNGARTAYATHTGYGAYYTNGARGGNYTN ATHTCNTAYYTNGAYGARAARGTNGGNGCNGGNCAYGTNTGYYTNTGGTGYAAYGARAAR GGNAARMGNTTYCAYAAYACNAARGAYGTNCARMGNCAYATGGTNGAYAARGGNCAYTGY AARATHYTNCAYGTNCCNGARACNATHTTYGARTTYGCNGAYTTYTAYGAYTAYTCNAAR AGYTAYCCNTCNGARGARGGNGTNGTNTCNAAYGTNGAYCCNTCN---GAYCCNGTNGAY ATHMGNGARYTNGAYGGNGAYGGNTAYTCNYTNACNYTNCCNTCNGGNGCNGTNATHGGN CAYMGNTCNYTNATGCAYTAYTAYMGNCARAAYYTNGTNCCNCARYTNCAYGARMGNACN MGNGCNGTNYTNCCNAARATGYTNGCNCARTAYAARGCNYTNGGNTGGACNGGNGCNACN GGNACNGCNGTNGARCARMGNGCNAARGAYYTNCARTAYATGCARMGNGTNMGNAAYMGN CAYTTYATGMGNGTNGGNGTNAARGCNAAYAAYYTNMGNYTNMGNATGMGNYTNCARAAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATHTGYACNGCNTGYGGNTAYAGYTCNATHGAYAAYYTNATHCARGAYAAYGCNGAY TAYYTNATHAAYAGYGTNTCNYTNMGNYTNMGNCAYTTYAGYCARAAYCARMGNACNCCN MGNATHYTNTGYGTNATGYTNAARTAYTGYTCNYTNGAYYTNYTNCCNYTNGTNCAYCAY AGYATHGGNGARATHYTNGAYTCNYTNGAYGAYCAYTAYACNGAYGAYYTNGTNYTNTTY ATGCCNGTNYTNYTNGARYTNACNAAYGCNATHGGNGGNTGGTTYCCNACNACNGCNMGN AAYACNMGNCARCARAAYAARAGYGARMGNAAYACNGCNCAR---GARAARTCNACNGTN TCNTTYYTNGTNGARTAYGTNMGNYTNAARMGNATHTCNGARYTNGARATGGARGAYGAR GAR------------GAYGARGCNCARGARGARMGNTCNATGAARGAYATHGARMGNGAY YTNGARMGNYTNAARGARGCNMGNCARGCNGAYAARCARGGNGGNGARGARGGNATGGAR GARGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARYTNGCNYTNATGYTNCARAAR AAYMGNCCNGTNGTNGTNGAYGARGGNCCNYTNAGYCCNACNAARACNTTYAGYATHGAR CCNYTNGAYGTNGCNGCNCAYYTNAARYTNYTNGGNGARTCNYTNAGYATHATHGGNATG MGNYTNCARGARCAYAARGGNATGATHGCNGTNCARGGNAGYYTNTCNGTNYTNYTNGAY TCNYTNYTNTGYGCNTGYGGNCCNYTNYTNTGYYTNACNCARCARYTNCCNGGNATGGAY GGNTGYTCNCCNTCNGTNCAYGCNCARACNYTNGAYAGYGTNGCNTAYGTNATGCCNGGN YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATHGARTAYTTYYTNGGNYTNACNCCNACNGGNATHGTNGTNTAYAARCAY AARTCNAARGTNGCNAGYTAYTTYTGGCCNMGNGTNACNAARGCNTCNCAYAARTCNAAR ATHTTYATGATHAARGTNAARGAYAARAGYAAYGAYGARCAYGTNTAYGCNTTYGARYTN GCNTCNAARTCNGCNTGYAARCAYYTNTGGAARTGYTGYATHGARCAYCAYGCNTTYTTY MGNMGNCARCARMGNMGNGTNAGYTCNGARTCNMGNYTNAAYGCNGAYCARATGTAYAGY ACNATGGARGGNGGNACNGTNACNGTNATGGGNCARCCNCARCCNGTNMGNGCNCCNMGN CAYMGNTCNYTNCCNGARYTNCARGGNAARGARTCNCCNMGNAGYGTNAARTCNGCNCCN TGGGARTCNAARTAYGAYTAYGGNYTNTAYACNTCNGGNCAYGARTCNCARMGNGGNCAY TAYGGNMGNCARTCNMGNGCNATHTCNGGNAGYGAYAGYGARAGYGGNATHAGYCARMGN AARAARTAYTTY------------------------------------------------ ------------------------------------------------------------ ---------------------------------CCNGCNCCNGGNTAYGGNCARCCNGCN CCN---GGNTAYGGNCARCCNGCNCCN---GGNTAYGGNCARTCNGCNCCN---GGNTAY GGN---------------------GCNGCNCCNTAYCCNCARCARCARTAY---ACNCAR GGNTAYCCNCARGGNAAYTAYCARGGNCARCCN---CARCARGTNGTNTAYATHMGNGAR GARMGNMGN------GARAARGAYAAYTCNGCNGARACNTGYTGYATHGTNGCNYTNTGY AGYGCNYTNYTNTGYTGYTGYYTNATG--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TAYAARGCNYTNGTNCCNAGYAARAAYGTNCARAAYAARAARTCN GGNAARGARGCNTCNMGNGTNAAYGGNAAYGTNMGNGARATHTCNCCNYTNAGYCCNTCN AAYAARCCNAGY---AARGARGGNTCNMGNTAYAGYCCNACNCCNGAYYTNGCNATHGTN ACNCARCCNAARAARYTNGGNGAYAARAARAGYGAYTTYYTNMGNGCNATHMGNAAYGAR AGYTCNGTNMGNAAYGGNGARGTNTGYCARAAYCARAAYCARAAYGTN------AARAAR CARGARTCNAARCARGGNGARGAR------------GAYATHTTYAARGTNAGYTCNATH TGYAAYMGNYTNAAYGGNGAYMGN---------------GARGTNGAYMGNAAYGARAAY YTNYTNAGYYTNAARGARGAY---AGYYTNAAYGGNGAYAAYGGNGAYGCNYTNATHGAY CAYGTNGAYCAYATHACNYTNTCNGGNGARGARGARGARMGNMGNYTNYTNYTNTCNATG GGNTGGGTNGARGARGAYAAYACNGARTAYGTNATHACNGARGAYGARATHMGNGARTTY CARAAYYTNYTNCARAAYTAYTGYCAYGGNCARAARAAYGGNYTNAARTCNTCNYTNMGN AGYGCNYTNGAYMGNAARTTYGGNGCNGAYTCNACN------YTNAAYGGNATHCCNTCN GAYGARAARAARACNGAYAARGTNYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYGGNMGNTAYCCNMGNGARTAYAAYCCNAARGTNCAYGGN CCNTAYYTNCCNGGNMGNTTYTAYGGNAARCCNGAYACNCCNTTYGGNCARGTNAARYTN GGNGAYYTNGGNGCNTGGTTYGGNMGNMGNAAYAARAGYCCNCARTCNATHTGGGGNAGY GTNCAYMGNGGNTAYTGGMGNTGGGCNACNAARAAYYTNCAYGTNMGNCARAGYGGNTTY GTNCCNTTYGGNCARGCNGCNATGYTNATGTCNATHTTYTTYTTYGGNYTNYTNTAYAAR GARMGNAGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TAYAGY AARACNMGNACNGARYTNGARGAYAARACNGTNGARTCNGARAARYTNMGNGCNYTNCAR TCNCAYTCNGCNCARCARCARATHATHYTNAAYCARYTNAARGGNMGNYTNGARGARCAY GARYTNGAYAARGAYCARGAYATHAARTCNAARYTNGCNACNATHGARGAYYTNCAYCAY MGNYTNAARTCNAAYATHGAYAGYATHCAYCARYTNAAYCARCARYTNAGYACNYTNCAR AARGAYAAYATHMGNATGMGNAGYGARYTNGAYMGNGARATHGCNACNMGNCARACNYTN GARATGCARATGCARGGNAARGAYCARYTNGTNGARTCNYTNMGNTCNCARYTNGAYTCN AAYACNTAYAARCARYTNYTNGARAARGCNGARACNTAYAARGAYCCNGARAARYTNGCN MGNACNGGNTTYAGYAARACNGCNGAYAAYTTYGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AGYCCNTCN GARYTNGTNGTNMGNAARMGNACNMGNGGNCARMGNGAYMGNYTNMGNCARATGMGNCAR GAYAAYMGNMGNGTNACNGTNCARGGNYTNGCN---------AAYCAYCCNGGNTCNTCN GGNYTNTAYGAYGAYAGYYTNTCNGAYTAYAGYGAYCCNCCNMGNCCNGARGTNTCNGAR AAYYTNGTNTCNGCNTAYAARAAYATGACNAARGAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AAYCAYMGNGAYTAYCAYTAYTAYCAYCAYCAYCAYCAYGAYMGNCCNCARCARACNACN GCNCCNYTNGGNGAYMGNAAYTCNTGYAAYAAYTCNAARCAYACNGAYGTNCAYCARGAR AARCCNGGNTTYYTNGGNMGNTCNTTYGCNTCNTTYMGNGCNATHMGNAARCAYAGYMGN AARAGYAARAAYGAYAAYGARCAYTGYYTNGAYGARAAYGGNAARAAYATHTCNTGY--- ------------CCNAAYCCNAARAARAGYGAYAGYCARAAYGGNGCNCAYAARAARACN CCNAARCARACNAAR---------------TGGMGNAARAGYAARCAYAAYACNMGNGAY AAYCAYGGN------GAYGCNTGYTGGCAYTCNGAYAGYGARGCNAARGARCAYAGYCAY MGNGTNTAYCAYCAYCARAAYGARGCNGTNCCNTAYGCNACNATHAAYMGNTTYCCNATH MGNGARTGYACNATH------------------------TCNCCNCAYTTYACNGCNGTN GAYGCNCCNAGYYTNGARAAYGTNTCNATHTCNGGNTAYGAYTCNGAYGTNTCNAARAAY MGNTCNGTNMGNCCNMGNTCNMGNATHAARACNAAYCCNTGGYTNCCNTCNCCNCARCCN TCNYTNGCNYTNGGNMGNMGNATHAAYAAYGAYMGNTCNCARGAYYTNCCNGARGAYTCN ATGAAYTTYCCNMGNTCNGCNATGAAYGAYYTNAAYACNAARMGNCCNAARTCNMGNCCN AAYTCNATHYTNTCNCCNAAYTCNGARTTYATHGCNYTNGCNGAYAAYATHGARCARYTN GCNAAYAAYATHAGYTTYGARTAYGARGAY------------------------------ ACNTGYCCNAAYTGYAGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AGYTCNTCNAARAARAARCCNAARGGNATHYTNAARAGYTCNAAYAGYGTNGAY CAYAAYAARAARGARYTNGARTGGGAYGARATGAAYATHYTNGCNACNCAYCAYCCNCCN GAYAARGAYTAYGGNTTYATGAARGTNGAYGARCCNCCNACNCCNTAYAGYAAYGCNGCN ATHTCNGAYCAYGARGARGAYGGNACNYTNGTNAARAARMGNGGNAGYGTNGAYMGNGTN GCNAGYTTYGAYCCNACNGAYYTNGCNTCNMGNYTNGCNTCNAARGGNAGYGAYATHGGN CARAARTAYGAYGAYGARGAYGAYGAYGAYGAYGAYGAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATHGAYATGMGNATHACNCAYTTYGAYGTNGGNGAR ACNATHGCNCARMGNMGNMGNMGNGCNGGNATHTTYAARACNAAY---CCNGGNCCNCCN GARMGNMGNAGYATGATHTGYAAY---ATG---TCNAGYAGYTAYCARGTNACNMGNATG MGNAAYYTNTCNGGNGGNAGYAGYGGNAGYGCNGCNAGYGGNAGYAGYAGYGGNAGYTCN TCNAAYYTNGAYAAYCARTAYTCN------CCNGARAAYCCNYTNTAYTTYTCNYTNGAY ACNACNCCNTTYGCNAAYACNTCNCCNGTNCCNCARCAR---------AAYGARGAYTCN YTNTCNAAYMGNAARYTNGAYMGNAGYYTNAGYGAYAGYGAYAGYGARMGN---AGYAAY GGN---------TCNCARMGNTCNGTNAAYTCNAGYMGNTAYAARACNGARYTNTGYMGN CCNTTYGARGARAGYGGNTCNTGYAARTAYGGNGAYAARTGYCARTTYGCNCAYGGNGCN CAYGARYTNMGNAAYYTNGCNMGNCAYCCNAARTAYAARACNGARCCNTGYMGNACNTTY CAYACNATHGGNTTYTGYCCNTAYGGNCCNMGNTGYCAYTTYATHCAYGARGAYGAYAAR ACNGAYAAYTCNGGNAGY---------------------------------------ACN AARACNTCNAGYAGYGGNAGYAGYAGYCCNTCNYTNAGYCCNACNGTNAAYGARCAYAAY ---------TTYTCNTAYACNGAYTCNTCNCAYACNCARGTNGAYAAR------------ ---------------TCNYTNTCNGTNAAYATHAAY---TAYGGNAAYGAYYTNAAYTCN YTNGARCAR------------CAR---TTYAAYTCNGCNYTNAAYYTNAAYCAYGCNGAY TCNTCNMGNAAYGCNTTYAAYAAY------------------------------------ ---AAYAAYACNTCNGARGARTTYGAYATHTTYAGYTCNATHTCNGTNTTYAAYGCNGAY GARGTNACNGTNGAYACNTCNCCNAARTCNACNTCN---------TCNTAYTCNTCNTCN CARTCNAGYCARYTNGAYAAYTAY---TCNTAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARAGYACNTAYGTNGGNGAYATHATHAARMGNAARGTNGGNTTY CCNCARCCNACNGCNTGYTGYAARCCNYTNMGNTTYAARGARTTYATHATHTCNTAYGAY TCNMGNAAYMGNATHCCNAAYTGGGTNTAYGARCAYYTNAAYMGNAAYAGYGTNTTYAAY GARGAYCCNTGYAAYCARATHAARMGNGCNTGY---MGNAGYGAYAARGAYMGNCCNAAR TTYACNCCNGAYTGYMGNATHCAYGGNTAYCAYMGNGCNGAYGCNAARGAYTAYTGYGAY ACNGARTAYGARATGGGNYTNATGGCNAAYCCNGARAAYTAYCCNTTYTGYCARGARGCN TAYTGYGARGGNTTYACNATGACNAAYGTNGTNCCNCAYGTNCCNGGNTTYAGYTGYGGN CCNTGGTAYGAYYTNGARAAYTAYATHMGNGAYAARYTNGTNMGNAAYAAYAARAGYGTN TAYATHTGYTCNGGNCCNYTNTTYYTNCCNGTNGARGAYGGNGAYAARATGGTNAARTGY TTYGAYGTNYTNGGNGAYGGNGARGTNTCNGTNCCNACNCAYTTYTTYAARGTNATHGTN ATHGARACNGARGAYGGNCARYTNGARYTNGARACNTAYATGGTNCCNAAY---GCNCCN GGNGAYGGNACNGARACNAAYYTNGAYGAYTGGYTNACNCCNYTNTGYCARATHGARCAY CAYTCNGGNYTNATHTTYTTYCCNGAYAARAAR---TGYTTYAGYAGYAAYAAYAARMGN MGNGGNGCNAARYTNCAYGCNYTNYTNMGNMGNATHGGNMGNTCNCAYGTNCAYTCNGAY MGNTTYGARAARAGYATHATHAARTTYTGYCAYCAYTTYTCNGARYTNGAYGCNTGGGAR ATHGARAGYTGYGGNTAYCARCAYGTNAAYYTNAARACNAARYTNMGNATHYTNAARAAY YTNYTNGARTGYCARTTYGAYTTYAAYGTNAARTTYAARGARAARGTNAAYGARCARGAY GCNGARACNATGMGNTTYYTNCCNATHGGNMGNGAYAARGARGGNYTNGCNTAYTGGTAY TTYYTNGAYAARGAYYTNAAYYTNYTNATHTAYAARGARGARCARGAYGAYGARGTNGCN GAYTCNTGGCARYTNGTNTGYAGYGAYMGNCARGARYTNGCNGARYTNGTNACNTCNYTN CARCAYAGYTGYCAYGTNAARGARGARGARAAYACNGARACNAGYCCNGCNMGNGARGGN GAYTCNGAYAARACN--------------------------------------------- ------------MGNMGNGAYGTNAARAAYCCNAARACNGTNTCNGARAARGARATHGTN AGYCAYAARGGNACNGTNMGNGGNTTYACNAAYMGNGTNMGNGCNGGNATHGCNACNTTY TGGGCNCAYCCNGAYGAYGARMGNAAYTAYMGNCARYTNGARCARGGNAARATHATHGTN TAYGGNACNTCNATGACNGTNGTNMGNGARACNAGYGARMGNTGYAARACNGCNMGNMGN ATHYTNCARAAYCAYATGGTNMGNTAYGARGARMGNGAYYTNTAYATGAGYAARGARATH CARCARGARYTNAARCAYMGNYTNGAYYTNGARGGNATHMGNAARATHATHYTNCCNCAR ATHTTYGCNGAYGGNYTNYTNATHGGNGGNGCNGGNGAYYTNGARMGNYTNAAYGARGCN GGNGARYTNMGNGCNYTNYTNGARGGNTAYCARAARATHAAYGTNMGNTTYGCNTGYGAR CARTGYGGNGGNTAYMGNTTYACNCCNTGYGARTTYTGYCAYGGNAGYAARMGNTCNYTN ATHMGNCAYCAYGTNATGGARGARTTYGTNGCNYTNMGNTGYATGCAYTGYGAYGAYCAY GGNYTNMGNMGNTGYGARATGTGYAARGAYCARCARGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CCNGAYATH YTNMGNAARCAYGAYATHCCNCCNACNAARGGNATHYTNYTNTAYGGNCCNCCNGGNTGY TGYAARACNACNYTNGTNMGNGCNGCNGCNACNTCNTGYAAYGTNTCNTTYYTNTCNYTN AGYGGNGCNCARGTNTAYTCNGCNTAYGTNGGNGARTCNGARMGNYTNATHTCNCARGCN TTYCARAARGCNMGNGCNYTNGCNCCNTCNATHYTNTTYTTYGAYGARATHGARTCNYTN GTNGGNAARMGNACNATGCARGCNGGNCAYAGYMGNGTNCARGARMGNATHYTNTCNACN ATG--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------MGNATGTGYMGNGAYAAYGCNGCNYTNATGTCNAARYTNGAR AARMGNAAYGARGARGCNMGNTGYYTNTCNGCNCAYAARTCNGCNYTNAGYMGNGARMGN GAYGARYTNYTNGCNYTNYTNGAYGTNTCNGARMGNATGAARTAYGARCARGGNAARAGY YTNATHGCNGARGARGARTAYGGNTCNTTYTCNTCNACNGARYTNGCNGTNYTNGGNGCN TGYAARTGYMGNGGNTCNGAYCCNGARCCNTGYGGNTGYGCNCAYGCNGCNGCNAAYYTN MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNTAY AAYAARCAYYTNYTNGTNACNAAYGTNGTNACNTGYGGNACNYTNYTNGGNGTNGGNGAY TTYATHGTNCARCAYATGTCNAAYTTYTGYTTYAAYTGYAARAARAARTAYGAYTAYGCN MGNACNGGNMGNATGATHGCNATHGGNTTYATHYTNGGNCCNTTYAAYCAYTAYTGGTAY TCNTTYYTNGAYAARYTNGTNACNGGNCARGGNYTNCARGTNGTNGGNAARAARGTNATH AGYGAYCARTTYGTNGCNGGNCCNTTYTTYTGYTCNTCNTTYYTNATHGGNACNTCNYTN YTNGARGGNTCNGGNGTNCARGGNGCNAARAAYGARYTNGARGAYAARTTYYTNAARATH TAYATGGTNGAYTGGACNTTYTGGCCNATGGCNCARTTYATHAAYTTYMGNTTYATHCCN TCNCAYTTYMGNGTNYTNTAYGTNAGYYTNGCNACNYTNGTNTGGAAYTCNTTYYTNTCN TTYATGAARCAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNAAY ACNATHCAYGTNGAYACNGAYYTNGARACNGARCARAAYGAYCARTCNGTNCARGCNAGY YTNYTNYTNGTNCARGGNYTNMGNTAYAAYGGNGAYATHTCNAARAGYACNGARGAYAAR ACNTCNTCNGARAARAARCARATGYTNGARYTNATHGAYCARCARCARCARACNGARGAR AAYGARYTNACNTTYAARYTNGGNYTNGARCARAAYGARGARGCNGARAARYTNMGNAAR GARTAYAGYATHMGNAARMGNATGGGNATHAARGAYATHCARCARAAYTAYATHTCNGAY GTNATHAAYGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNGCNGAYAARAAYGAYGAYGGNTTYATHTCNTGGGARGARTTYGTNTCNTAYTTYTCN GAYGGNGTNATGGGNAARGARGARYTNCARGCNYTNTTYAAYGARATHGAYTCNCAYAAY ACNAAYAAYATHGAYGTNGGNGARYTNTGYGCNTAYTTYTCNCARCAYYTNGGNGARTTY AARGARATHTTYGGNYTNATGGARGARATGAGYGTNAARYTNACNAAYGTNYTNTTYGGN ACNGCNAARGTNTAYAARGARTCNTCNMGNACNGAYCARTTYGTNAGYMGNTTYYTNATG MGNGARATHAGYAAYCARATGATGGCNYTNCARGGNCCNYTNGAYCAYGCNACNGARGTN ATGGAYCARCARGCNMGNGARGAYMGNTCNGAYATHATGCCNYTNGARGTNGGNGAR--- ATHAARGCN---GGNACNGARAGYGGNGTNGTNCCNGGNMGNGTNGGNMGNMGNGCNAAR MGNCARATGAGYACNAAYAGYTCNYTNGGN---------------------GGNACNAAY CCNGCNTCNATGACNAGYCARYTNGARAARYTNAGYAGYYTNATGGAYAARYTNGARAGY AARATHMGNTTYGARAAYTTYMGNGAYGARGARGTNGTNACNAGYMGNAAYGAYACNATH YTNATGGTNCARMGNGARTTYATHGTNAARMGNGAYAGYYTNGARGARTTYMGNGCNCAR YTNMGNTCNTAYGTNGAYYTNACNCARGGNTTYMGNGGNTGYMGNAAYGTNAGYGTNMGN GAYATHMGNCCNACNAAYTCNTTYCAYGTNTAYGARGTNTGGTGYGAYGARGAYCAYTAY YTNCARAAYTGYGGNAGYGARGCNACNACNAAYYTNGTNGAYAARACNGCNGAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATH TCNACNAAYMGNAAYAGYGAYATHMGNGCNTGYMGNTCNTAYGARMGNATGGAYAARGTN GCNTCNTCNYTNGGNCARCCNGAYGTNMGNYTNTGYGCNTCNAAYCCNGGNATHTAYYTN CAYMGNATHCAYGGNCCNAGYCCNGGNMGNTGGAGYAAYACNAGYGGNGARGAYAGYGAY CARCCNAGYGTNGCNGCNMGNGTNAGYGGNATGGTNGAYYTNYTNACNGARGARAAYMGN TCNYTNMGNGAYGARYTNGCNACNGCNACNGTNAARGTNGCNMGNYTNYTNAARTTYGAR GTNGARGTNGARAARATGCAYGARGCNCAYGCNTCNYTNYTNCARTCNCAYGARAARMGN GARACNYTNTGGYTNGCNATGMGNMGNAARYTNGARGARMGNATHMGNACNYTNGARACN GTNGAYGGNTGG------CCNGAYGAYGGNAARACN---GGNGCNAARTCNGTNACNGAR TCNGARYTNMGNACNAARYTNGCNGARAARGARGCNATHATHTCNMGNYTNYTNACNCAR AAYCARGARYTNYTNTCNAAYCARAGYCARYTNCARACNGARAAYATGGARYTNAGYGTN AGYYTNGCNGARMGNAARGCNCAYGTNGARATHGTNGARAARGCNYTNATGAAYGCNCAR GCNMGNYTNYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GAYATHTCNGARGCNGAYTAYGAYTCNGAY ATGGAYCCNAAYAAYGTNGTNYTNMGNMGNAARGTNCAYCARGAYGARGGNTAYGAYCCN GAYATGGAYCCNAAYAAYGTNGTNYTNMGNMGNAARCCNAGYAAYCCNAARTCNGARGAY TAYGAYCCNGAYATGGAYCCNAAYAAYGTNGTNYTNMGNMGNAARCCNMGNCCNACNAAY GCNACNMGNAGYCAYGCNATGGCNATGTCNACNGAYGAYGAYGAYCARGAYGARMGNCCN TAYAGYYTNTCNGCNTAYMGNAARAGYGTNAAYGTNAAYCARCAYACNYTNGAYCCNGTN GTNMGNAARAGYAARTAYAGYGGNCARTAYGTNGARGARGARGARATHGTNATGCCNACN TCNCCNMGNAAYCARMGNGAYAAYMGNYTNGCNGTNCARGARMGNGTNAARGARYTNCAR GARYTNGTNCARCARGARCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYTTYGARTCNTCNAAR GTNGGNACNCARGARTAYTGGGAYAAYACNTAYGARAARGARYTNGARAAYTTYTCNGTN TTYGGNGAYGTNGGNGARATHTGGTTYGGNGARGAYGCNCARCARMGNATGGTNMGNTGG GTNTCNGARAARCAYGARGTNCCNAARTCNGCNAARYTNYTNGAYYTNGGNTGYGGNAAY GGNATGYTNYTNATHGCNYTNMGNGARGARGGNTAYACNGAYYTNACNGGNGTNGAYTAY TCNGAYAAYTCNATHAARYTNGCNAARAARATHGCNGTNGCNGARGAYGCNACNGAYATH TCNTTYCARGTNTGYAAYATHYTN------TCNCCNGAYGARGCNYTNAARYTNCARGAY AGYTAYGAYGTNTGYYTNGAYAARGGNACNTAYGAYGCNATHAGYYTNAARAAYACNGAR GAYCCNACNGAYMGNMGNATGTAYGTNGCNCAYATHCAYTCNATGYTNAARAARAGYGGN ATHYTNGTNATHACNTCNTGYAAYTGGACNAARTCNGARYTNGARCARCAYTTYGGNAAR GAYTTYGARYTNACNGAYGARGTNCCNTCNCCNAARTTYACNTTYGGNGGNCARACNGGN CARACNGTNACNACNYTNATHTTYACNMGNAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AGYGAYTCNGGNAGYGAR GAYGTNAGYATGGTNTAYGAYGAYAAYGGNAGY---------------CARTAYGGNGAY GAYGTNTGYMGNGAYTTYYTNMGNAAYGTNTGYTCNMGNGGNAARMGNTGYMGNTAYMGN CAYCCNGTNCCNGARGAYGTNCARGAYCCNCCNCCNMGNMGNGARATHACNTTYTGYCAY GAYTTYCARAAYAAYGGNTGYTCNMGNATGAAYTGYAARTTYYTNCAYTGYAGYMGNGAY GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CCNCCNATHGGNYTNACNGAYCCNTAYYTNAGYYTNTCN CCNCARGGNCARGARTTYACNAGYMGNGTNACNTCNATGGGNTTYYTNMGNGCNAARGTN GCNMGNGCNGTNCARAARTTYGGNCARGAYGARAARGARGTNYTNGAYCAYYTNTTYGCN GCNGAYGTNYTNGTNGARAARAARTAYGCNCCNGTNCAYGTNGARGCNGCNYTNCARTCN TGYAARAAYGAYYTNGARAARGCNGARMGNTTYYTNCARATGCARACNCARYTNGARGAR YTNGGNTTYAGYAGYGARAAYGTNMGNGAYGCNYTNYTNTCNTCNGAYYTNAAYCAYGAY AARGCNYTNGAYYTNYTNACN------------------------AAYACNGARAAYMGN AAYYTNAAYGCNTCNTCNAGYAARACNATHATHTCNATHTAYGARCCNCCNGCNAARAGY CCNGTNATHACNGTN------GAYGGNYTNGARATHACNAAYGGNAARACNYTNACNTTY GTNAAYGGNGARTCNYTNTCNGTNYTNTGYGARGTNAAYGGNGGNTTYCCNAGYGTNTCN AGYGTNAAYYTNACNTGYCAYGAYGTNAARAAYGARACNATGACNTCNTCNAGYYTNGAR YTNGAR---------ATHTCNYTNCCNTTYCAYCARCARAARTGYGTNTGYTAYTAYGAR CAYGTNTCNGAYTGYTCNGARAGYGARACNTAYTTYATHTTYAAYGTNCARGCNGGNCCN GCNAGYGTNMGNATGGAYGAYAGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GCNGARGTNGTNTAYMGNCARAAYCCNATH ACNTGGCCNTTYGAYATHGCNATHYTNMGNTGYMGNTCNTCNACNGARCAYYTNCCNAAR CAYTGGAARATHCARGTNTCNAARCCNTCNGGNGGNGTNGAYGTNATHYTNAGYGGNTAY CCNYTNTTYGAYACNGAYYTNCAYYTNMGNCCNTCNYTNTGYCAYGGNGTNGTNTGYAAR GTNATHAAYAARMGNAAYMGNCCNGTNATGYTNCARACNACNTGYGCNGTNCAYCCNGGN GTNAGYGGNGGNCCNGTNYTNGAYGCNGARGGNAGYYTNGTNGGNATHGTNGTNTGYAAY ACNMGNGAYGCNGARACNAAYAGYACNTTYCCNCAYGTNAAYYTNTGYATHCCNGTNTGY GCNGTNTAYGARGTNATHAAYGTNTAYYTNTCNACNGGNGARACNMGNTGGYTNTCNCAR YTNGARATHMGNGAYCAYGARATHMGNCAYYTNTGGGARYTNGGNTCN------ATGGCN GAYYTNTCNYTNGAYGARTTYATHAARCARAARAAYGTNAARGTNCARATHAAYGGNCCN TCNAARGGNTTYGCNCARCARMGNACNYTNAARCCNAAYGCNAARTTYCARGGNACNGTN MGNCCN------------GTNCARMGNACNTTYGAYGCNMGNTCNAARYTNGGNCCNAAR ATHGTNACNGAYGCNMGNGAYAARATHATHACNAAYAARAARAGYGGNAARGGNGAYGCN MGNAAYAARATHGTNCARAARCARGTNCARAARGGNACNTTYGAYGCNMGNTCNATHYTN CARAARCARAAYAARAARACNAAYGGNGCNGTNGGN------------------------ ---CARCARGTNTTYGTN------------------CCNATHACNMGNACNYTNTCNAAY CCNATGGGNAAY---------------------------------AARCCNGGNACNCAR GTNGCNTTYTCNGGNAAYTCNYTNCARATHACNAARMGNGGNATGGGNMGNCCNCCNCCN TCNCCNAAYGTNAARGAYTCNGTNCCNATHATHCARATHMGNAAYGAYMGNTAYCARCAR MGNCARCARGTNCAYCAYACNTCNTGGTCN---TCNAAYCARCCNTCNCARCAYYTNCCN ACNCARCCNCARCCNGCN---------------------------TAYCCNGGNGGNGCN CARTAYATHCARACNCCNTCNTAYCCNCARGCNCAYGGNTAYTTYGAYYTNGAYAAYCCN AAYYTNCAY---GAYTTYCCNACNGGNGCNCAYAAYATHCCNAARATHAGYGTNTCNAAY YTNAARGCNGTNGARGCNGCNGGNATGMGNCCNGTNTCN--------------------- ATH---------CCNCARMGNGCNCCNCCNGGNGCNGCNACNYTNTCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GCNAAYAARGCNYTNGARMGNYTNTCNGTNGTNMGNTCNTGYCCN GGNGTNTGGGAYATHTTYATHGAYAARATGGTNGARATHCAYTGYTAYTAYGAY------ ACNGAYGCNMGNGARGTNYTNATHCARTAYGCNGARAGYAAYCCNAARAAYCCNATHGCN CAYMGNTAYYTNTAYAAYTTYAAYGARCARTTYGARGAYGARAAYGARGARMGNAARAAR AGYYTNGARCAYATHATHAARYTNGAYCCNAGYAAYCCNYTNGTNTTYGARYTNTGYTCN ATHYTNGARACNACNGCNCCNCAYAARGTNATHATHYTNTTYGAYTTYYTNGAYTTYGAY CAYTGYAARGARAAYYTNAARGCN------------------------------------ ------------------------------------------------------------ ---TTYTGYTCNATHATHGTNTCNTTYYTNGCNYTNYTNTCNATH------YTNGCNGAR TCNAARAARTCNCCNGARTGYTCNACNTGYAARGARATHGTNGAYAAYTTYCAYAARGGN YTNYTNGCNACNGCNAARTCNAAYTAYGGNGGNGGNAAYACNAAYTGGGARGARAARTCN YTNGGNTCNTAYGCNTTYAGYGARGTNMGNYTNGTNGARATHATGGARAAYYTNTGYAAR GAYAARTCNAARGARTGYCAYTCNYTNYTNGARGARCAYGARGAYYTNGTNGARAGYTTY TGGTTYAARGARTTYACNAARAARACNGAYAARGAYTTYYTNACNTTYTTYTGYATHGAR AAYATHAARGCNTGYTGYCCNAAYAAYACNTAYGGNAARGAYTGYYTNGCNTGYCCNGGN GGNAARGAYAARCCNTGYCAYGGNAAYGGNCAYTGYGAYGGNGCNGGNACNMGNAGYGGN TCNGGNAARTGYAARTGYAGYTCNGGNTAYACNGGNGARGARTGYACNGARTGYAARGAR GGNTAYTTYGARGARACNGAYGGNAARGAYGGNGTNGTNTGYAARGTNTGYGAYATHTCN TGYAARGGNGAYTGYTCNGGNCCNGGNCCNAARGCNTGYGAYGARTGYAARGAYGGNTTY ACNTCNGAYGARGARAARGGNMGNYTNGAYGTNGAYGARTGYAARGARGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGGNGCNTCN GARAGYAARMGNMGNGTNGTNGTNGARGAYGTNAAYGGNGARGGNGTNGTNCARATHACN GARGCNGTNGTNMGNMGNATGAARGGNYTNCCNGARGCNCCNGTNAARGARAAYAARGAY AARTCNAARCCNGAYAGYGARGTNAAYTAY------------------------------ ---------AARGARATGACNMGNGARATHGARAAYTTYTAYTCNGARAARYTNGARGAY YTNCARAARMGNAGYAARGARYTNCARGAYGTNTCNAAYGARCARTTYGCNAAYGCNGTN AARGARGTNGARCARAARTTYATGAARTAYACNACNTCNCCNGTNTGYCARAAYYTNCAR ACNAARGTNYTNGARTGYTAYCARAARAAYCCNGAYTCNATHYTNGAYTGYTCNTCNGTN GTNGAYGCNTTYACNACNTGYGTNGAYMGNGCNMGNTTYACNGTNTCNATGACNATGGAR AARTCNAAYAGYYTNGCNGCNATGGARGTNGARMGNYTNTCNAARYTNGGNACNYTNMGN YTNCARCARGGNTTYCCNGARAARGCNYTNGARGCNTAYAARGCNGCNTAYAARAAYGCN CARTCNYTNAGYTCNCAYGGNTAYATGGTNMGNGCNTGYGCNTTYAAYYTNGGNGCNATG ATGATHTCNATHGGNAAYTAYYTNGARGGNATGAGYTAYYTNAAYAARGCNYTNCCNCCN GAYGGNAARMGNGAYGGNMGNTCNAAYGGNGAYYTNTTYTTYAAYTTYGGNYTNGCNTAY GARGGNYTNAARAAYTCNGCNAARGCNAARCARCAYTAYGARGCNGCNYTNAARGARTAY AARGCNGARCAYAAYAAYGTNAARATGGARATHGARACNATHGGNMGNATHATHMGNYTN TGYYTNGARAAYAARYTNYTNTCNGARGCNAAYGAYTGGATGAARCARYTNACNCARYTN CAYTCNAGYCARGGNAAYGTNGARAARGARYTNCARTCNCARGTNGARMGNTCNAGYATH YTNYTNATGATGGGNMGNGCNCARGAYGCNGARCARGTNGCNGAYGARTGYYTNAARGCN YTNGAYAAYTCNCCNTCNTCNATHGCNYTNGCNAARATHTAYAGYGAYYTNTCNGTNGCN TAYACNCARATHTTYCARTAYGAYAARGCNYTNYTNTGYAGYGARMGNGCNYTNCCNYTN GTNGARGAYCARAGYTGYGAYGTNYTNTTYGCNGCNATHATHTAYCARAAYYTNGGNGCN ATHTAYAAYTAYATHGGNAARTTYGAYAAYGCNGTNACNTAYCAYGAYAARGCNTGYAAR GTNTTYGGNCARYTNAGYATGMGNGTNAARCARGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GGNCAR ACNGCNGTNYTNAAYGTNYTNAARGCNYTNAARTTYCCNTGYGARAARTCNGTNGTNTGY AARACNATHAARGCNAAYYTNMGNAARGARGAYAARGAYATHCCNGARTAYYTNTTYTCN MGNGCNTGYGCNGGNACNACNGCNGAYGARYTNATGACNGGNATHGARAARYTNACNAAY GGNGCNGTNGGNGGNMGNTTYTTYCAYTTYTGGCCNCARMGNAARGTNAARYTNYTNCAR TGGYTNGCNTAYTGGATGAARMGNGGNGCNATHCCNATGGCNACNYTNAAYYTNCARYTN GGNCCNCAYTCNATGTGGGARGTNCCNGAYTCNTGGCAYCAYCARATGGTNTAYGGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TCNTGYATGGGNATHAARATHGTN GTNGAYTGGTTYMGNAARMGNGGNCAYAARAAYATHACNGTNTTYGTNCCNCARTGGMGN AARGARGCNTCNMGNCCNGAYGCNCCNATHTCNGAYCARCAYATHYTNACNGARYTNGAR ATGGARAARATHGTNGTNTTYACNCCNTCNMGNMGNGTNGGNGGNACNMGNATHGTNTGY TAYGAYGAYMGNTTYATGYTNAARYTNGCNGTNGARATHGAYGGNATHGTNGTNTCNAAY GAYGTNTAYMGNGAYYTNGTNMGNGARAARGAYGAYTTYMGNCARGTNGTNGARAARMGN YTNYTNATGTAYTCNTTYGTNCARGAYATHTTYATGCCNCCNGARGAYCCNYTNGGNMGN CARGGNCCNTCNYTNGAYAAYTTYYTNMGNATHAARCCNGCNGARCCNAARAAYAARCCN CCNAAYTGYACNTAYGGNAARAARTGYACNTAYGGNYTNAARTGYAARTTYTAYCAYCCN GARMGNMGNTAYGCNCCNGAYAARATGGTNGCNGARAARYTNAARGARAAYGCNGAR--- ------YTNAARCARAARGCNMGNAAYGCNGAYGARAARMGNMGNACNAARYTNAARYTN TCNMGNACNACNTCNATGYTNCCNCARAAYTTYGAYGARAAYTCNYTNTCNGCNGARGGN AARAAYATGAARCCNGCNYTNCARCAYTCNATHTCNGTN------------MGNTAYYTN ACNGARYTNMGNYTNAARATGGARGCNGARYTNTCNGAYYTNTTYCARCARAAYCCNCCN CAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNGARATGGAYTAYAARAGYATGGAYAAYTAYYTNGTNGARCARATGGTN--- ---ATHAARYTNGARYTNGARAAYAARAARAAYGGNGGNTAYAARGTNCAYATGTCNCCN YTNGARATHGCNGAYYTNGGNCAYCCNAGYATHCARCARYTNATHCARYTNCAYCCNACN YTNTCNYTNGTNTTYCARCAYCARGCNGTNAARYTNAARAARAARAARGGNTAYGGNGAR GCNGTNTTYMGNACNGTNACNGAYYTNAARGARTTYGTNTAYCARYTNACNCARGTNAAR GTNTGYGARMGNTGYYTNTAYGTNTCNATHTCNTTYGAYYTNCCN---------GAYTTY AGYATGTCNTTYAARATHAAYYTNAAYCAYACNMGNAARYTNATGGAYYTNATHAAYAGY GGNGARGAYCCNGTNATHAAYAARCCNGTNCCNATHGAYAARAGYTCNCAYAARGTNATG TTYGARAARGTNCCNTCNGTNGCNAAYGCNGCNTTYATGCAYAGYYTNTTYCCNTTYACN AAYAAYGTNCAYATHAARCARTGYATHGAYAARAARACNGCNAARTCNAARTAYTAYGGN CCNYTNACNGTNTGYTAYATHAAYGARAAYTGGYTNGAYGCNGTNATGGCNTGYTGYACN GAYTTYGCNGTNAAYGAYTTYCCNYTNACNGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYMGN GTNYTNTGGATGTGGCAYGARGCNMGNMGNCARGARAARAARATHMGNGGNYTNATGGTN GAYYTNAARMGNMGNGCNGAYMGNMGNAARGARTTYTAYGARAARATHAARCARGAYCCN ACNCARTTYYTNMGNATGTAYGGNMGNCCNGTNAARATHCAYYTNGAYCCNTCNGTNGCN ACNGCNGCNGARGGNCCNCARAGYATGATGGCNTGGCARGGNGAYAAYACNAAYATGATH GAYMGNTTYGAYGTNMGNGCNAAYYTNGAYTTYATHAAYGARTAYAAYCCNGGNAARAAY TCN---AGYAARTCNGGNAARYTNGAYAARGARGARMGNYTNGCNAAYTAYGARMGNTAY MGNACNYTNGTNGARAAYGARGCNGCNGGNYTNACNGARGARCAYTCNYTNCAYCARATH TAYYTNGAYGARCAYTTYGGNACNATHAAYAARAGYGGNGARGARGARAARAARAARAAY GCNGAYAARAARGCNGCNATHGGNTAYGTNTAYGARGAYAGYACNCCNGTNGAYAARGAR YTNACNAAYGARATGAGYGARGARGARAGYGAYGAYGAYYTNGAYATGGCNGAYYTNGAY GTNACNATHGAYGTNGAYAARYTNACNCCNGAYYTNTGYGTNGARGTNAAYCARATHGCN GGNCARTAYGGNATGATGGARGAYGAYTTYGTNMGNYTNYTNMGNAARGAYAARGARGAR YTNGARGCNYTNAARGARGCNMGNCARYTNGARGARGCNAARGCNCARTTYTCNGGNMGN AARTCNMGNMGNGARMGNMGNGCNATHAAYGARMGNMGNCARAAYCCNCARMGNTTYGAR MGNCCNAGYTAYGCNGCNMGNGAYAGYCCNAARTAYGARCCNTAYAARMGNCCNGGNTCN TCNTCNMGNTCNMGNTCNMGNTCNMGNTCN------CCNGARAARACNGARGTNAARTTY ATHACNAGYTTYGGNGGNAAYGARAGYGAYGAYGARGGNAGYGGNGTNGTNCARGGNCCN TCNYTNCCNGCNTCNATG------ATGACNGTNAARAARGARAAYAARATHGARACNCCN AARYTNTGYGAYACNCCNTGGYTNCARTCNGGNGCNGARACNAARTCNTCNMGNTCNMGN TCNCCNTCNAARCCNMGNYTNAAYAGYMGNTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATHTCNTCNYTNTGYGCNGTNYTNAAR YTNGAYGARCARGARATGGCNMGNAARCARGCNAGYGARTGYYTNGTNTCNATHAGYGGN YTNGARGCNMGNATHGAYGAYMGNYTNAARGCNTAYAARGCNAARAGYGTNACNGAR--- ------AGYATGGAYTAYAGYACNTGGMGNGARGCNGGNATGTCNATHCAYCARATHAAR ACNTGYYTNAAYGARGTNTCNAARYTNATHTCNYTNGCNTGGATHACNGARYTNCCNCCN GTNAAYGAYCARGGNAARTTYTAYGAYCCN------------GARACNCARAARYTNMGN TCNGARYTNATHGARYTNAARTCNAARTAYTCNYTNYTNGAYCARTCNGCNAARGAR--- CARAGYAARYTNCAYGTNTCNGCNCARMGNCARAARAAYTGGGARCAYTCNGTNTGYMGN CAR---------AARGGNAARMGNTCNMGNAGYYTNTCNGARTCNTTYGAYGAYTAYAAY AAYATGATGGARAAR---------------GAYATGTCNMGNGARATGYTNGAR------ ------MGNGAYYTNGAYGGNGARAARTTYTCNCARGTNAAYGAYMGNAARATHYTNAAY CCNGARYTNAARMGNCARTAYGARCARATHAARMGNTCNTAYGCNAAYATHYTNTAYAAR TGGGGNYTNYTNAAYCARMGNACNCARGTNYTNAARCAYACNGTNTCNGTNGARTCN--- AGYCARAARATHGARTTYTCNATHCCNTGYTCNAAYTGYAAYGARAAYGCNGCNACNGTN AARTGYAAYCARTGYCAYTAYCCNTCNYTNAAYTGYTCNATHTGYCAYATHGGNGTNMGN GGNCCNGCNAAYATGTGYTTYGARTGYGGNCAYGGNGGNCAYTCNTCNCAYATGATGGAR TGGTTYCAYACNAAYTCNYTNTGYCCNTCNGGNTGYGGNTGYAAYTGYYTNCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TGYYTNGARGCNAAYYTNYTNCARMGNGAYACNGARATH CARAGYGAYGAYGTNGARAGYAGYMGNCARAARYTNTTYTCNYTNAAYAARTAYATHGAR GARCARAARCARGCNATHMGNGTNAARGARGAYAARATHAGYTGYYTNCARMGNGARYTN GARGARGTNAARTTYGCNGCNGARAARACNGARAARATHYTNCARACNCARATHGAYGAY MGNGAYAARMGNYTNAARGCNTCNCARGAYCARGTNYTNGARYTNGARAAYGCNYTNTGY YTNTGYMGNAGYGARGTNTGYTCNCAYYTNAARACNATGGAYGAYATHMGNGCNCARTAY GARTCNGARYTNGARCARMGNGAYTCNTGYATHMGNAARYTNAARGARGAYYTNMGNTGY GCNGTNGARGARYTNAARTGYAARATGGARGAYAAYGGNTCNYTNGARMGNTCNYTNGCN GARGCNMGNAGYAARGTNCAYCARATHTGYGGNCARYTNAARGARGCNGAYACNAAYATH CARTGYYTNAAYATHAARATHGTNGARATGGARAARCARYTNYTNAARGARAARTCNAAY TGGATGAARGARTCNGARGARATGGAYMGNMGNATGCARCARTGYTGYAAYAAYYTNGCN ATHGCNAAYAAYGARATHGAYATHYTNAARCARCAYYTNTCNGARAARAARGGNCARATH GAYTGYATGCARACNGARAARACNCAYATGTGYCARGARATHAARAARYTNAGYGAYCAR GTNTGYTGYGTNCARGARCARATHAARAARATGGARATHGAYAAYCARGARYTNTGYMGN CARYTNCARCARAARATGGARTGYATHMGNGAYYTNGARAAYGTNATHMGNTCNAARGAY CAYGARATGAARTGYYTNACNAARTTYGTNCARGARATGGARACN------ACNGGNGAY AGYGGNGTNGTNCCNACNYTNGARGCNAAYATHAARGARYTNACNGARAARYTNGCNAAR TGYACNGARGARAAYAARTGYAARGGNACNATGYTNTGYGARTGYGARGARGCNTTYAAR CARTGYCARGTNYTNTGYAARGAYAARGAYAGYGARATHTCNYTNCARAARTGYCARATH GARGGNYTNAAYGARAARYTNAAYGAYMGNATHTCNMGNGTNGAYGARYTNGARMGNGGN ATHGARAAYYTNCAYAARGAYGTNGARMGNMGNATGATGMGNGTNGAYGARCARYTNAAR AARTAYGARACNGARYTNGCNGAYMGNYTNCARGARATHGCNACNYTNAARGARTGYGTN ACNACNTGYCARYTNAAYYTNTCNGARAARCARGAYGARYTNCARCARCARGARCARAAR AAYYTNYTNYTNGCNTCNGARYTNGARTCNYTNAAYYTNAARYTNMGNGAYGCNGARGAY TCNMGNGAYCAYYTNGGNACNCARYTNGCNGARAARAARGGNGARGTNAGYGARYTNACN CARCARYTNMGNYTNAAYMGNGARCARATGCARAARCARCAYGARGAYYTNGTNCARTGY MGNCARGCNYTNTCNTGYTCNCARMGNGAYTCNGAYAARYTNMGNMGNGARYTNGAYGAY GCNYTNGCNAGYYTNGARCAYMGNGARTGYGARATHAGYMGNYTNAAYGARGARMGNAAR TGYYTNATGGARAARGTNGCNCARATHTCNTGYCAYATGGARCARGAYACNTCNATGYTN MGNAAYCARYTNGCNGARACNAARTGYMGNYTNGARAARGARATGGARTGYYTNMGNAAY TAYTCNTGYCARGTNGARGGNAAYAAYACNTCNYTNAGYAAYAARYTNTCNYTNACNCAR MGNCARATGATGCARATGGARAARTGYTTYCAYCARAARYTNGAYACNYTNAAYMGNAAY TTYGAYGAYYTNAAYACNAARYTNAARGTNMGNGARGAYGARYTNYTNGCNTGYAARGAY TGYATGGAYYTNAARGARTCNGARATHACNMGNYTNAARAARMGNYTNTGYAAYGCNGAR AARGTNGCNTGYAAYGCNAAY------TGYCAYAAYAAYACNTGYYTNGAYGAYGARMGN YTNTGY---GAYTTYAGYGAYTTYCARCARGAYGAYGTNATHAGYTCNGARAGYTGYATH AAYYTNGCNGGNGGNGAYGAYGGNGAYMGNAARYTNYTNGCNAARGARMGNGCNTGGAGY GARGARGARGAYCAYCCNACNGAYGCNCAYGGNAGYTCNMGNAAYAGYYTNGGNGTNACN GARGTNCARGARMGNYTNMGNAAYAAYCARYTNMGNCARAARGARATHGARMGNCARYTN AARACNYTNGARGARGGNAGYCARGARGAYYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ACN GCNYTNGCNGTNGTNCCNTAYCARGARGARAARYTNATGCCNCAYGARAARAARCAYMGN ACNTTYTAYATHGCNGGNCAYGARTTYCARATHCARCARAAYTGGCAYAGYGGNGGNGTN GCNGCNGTNGTNTGGGAYGCNGCNYTNGTNYTNGGNGARTAYYTNGCNYTNAAYTCNGAY YTNGTNCAYGGNAARMGNGTNYTNGARYTNGGNGCNGGNACNGGNYTNTCNGGNATGGTN GCNTCNGCNYTNGGNGCNGAYGTNGTNGTNACNGARMGNGARGARGCNYTNTCNCAYYTN TCNTCNATHYTNTCNGARAAYGTNGTNGGNAARCAYTGGAGYATHAARGCNGARGTNYTN GAYTGG------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATHTCNYTNCCNGCNGAYYTNAAYGTNGTNGAR TGYAAYTGYAGYGTNTGYACNAARAARCARAAYCAYCAYTTYGTNATHCCNAARTCNMGN TTYGARYTNYTNCARGGNGARAARTCNYTNACNACNTAYACNTTYAAYACNCAYAARGCN AARCAYACNTTYTGYAARACNTGYGGNGTNCARAGYTTYTAYATHCCNMGNTCNAAYCCN GAYGGNTAYGGNATHATGCCNCAYTGYYTNGAYCCNGGNACNGTNAARTCNATHAGYACN TCNACNTAYGAYGGNCARCARTGGGARAARACNTTYAARACNTCNGAYATHAGYAARYTN TCN---TCNAARTCNCAYYTNGTNTTYGTNTAYGGNACNYTNAARMGNYTNGARCCNAAY TAYGARCARATHATHAAYAARGARAARGGNATGGCNGTNTTYATGGGNGTNGCNGARACN GTNAAYAARTAYCCNYTNGTNATHCAYACNCCNTAYAAYATHCCNTTYATGYTNAARGCN GARGGNCARGGNCAYAARATHCARGGNGARGTNTAYGARGTNGAYGAYCCNATGYTNGCN CAYYTNGAYGARTTYGARGGNCAYCCNCAYYTNTAYYTNMGNCARAAYGTNGAYATHYTN ATGAARAGYGGNCCNGAYGAYTCNCCNYTNCCNTCNYTNCARCCNAAYACNGCNCARAGY TAYTTYYTNCCNCARTTYAAYGARAARATGATGAAYYTNAARTTYYTNAGYAAYTAYAGY GCNTCNGCNTGYGAYCAR---CCNTAYGTNAARMGNTGYGAYMGN---GARGGNGCNACN TTYGARGAYACNMGNTGYAARTGYGTNTGYACNAARATHMGNGAYGCNCARGGNAARGAR ACNMGNTCNGTNTTYATHAAYACNACNAARAGYGARCARTGYGAYTGYGARCAYGTNGTN AARCCNATHACNTCNTTYYTNCCNTGYTCNYTNTGYCARTGYGARACNGARACNMGNAAY ACNACNACNATHAARGTNGTNGTNATHTTYATHATHTGYGTNGTNTCNATGYTNTTYGTN TAYATGYTNTTYYTNYTNTGYYTNGAYCCNYTNYTNCARAARMGNCCNGCNAARTCNTAY CARCARCAYACNAAYGARGARGTNAAYATGGARGAYTTYTCNAGYMGNCARGAYCARGAR ---------------CCNGGNACNTCNGCNCCNCARYTNACNGAYTCNATGTCNGCNMGN CARMGNTCNYTNYTNAAYATHGTNACNAARGARCARAARAARTGGAARGGNACNGTNCAR GARCARMGNMGNAAYATHTAYGAYMGNCAYTCNATGYTNAAY------------------ ------------CCNYTNYTNACNTTYGGNATHATHGCNGAYGTNCARTAYGCNGAYGTN GAYGAYGGNACNGAYTAYTCNAARACNMGNACNMGNTAYTAYMGNAAYGCNYTNAAYYTN YTNAARAAYGCNGTNAAYGAYTGGAARMGNTGYTCNGAYTCNATHTCNTTYGTNYTNCAR YTNGGNGAYYTNATHGAYGGNAARTGYAAYGGNGGNTGGAAYGCNAGYCARAARGCNYTN ACNACNGCNYTNYTNCCNTTYAAYTCNYTNCAYGTNTCNGTNTAYCAYYTNTTYGGNAAY CAYGARTTYTAYAAYTTYTCNMGNTCNTTYTGYYTNAARTCNCCNYTNAAYAGYTTYYTN TCNACNGARATH------------------ACNTGYCARGCNGAYTGYYTNTAYMGNACN TTYYTNCCNCAYCCNAARYTNMGNTTYGTNYTNYTNGAYACNTAYGARGTNAGYGTNYTN GGNTAYGGNGAYGAYYTNGARAAYGARAAYTAYGTNAARGCNACNTCNYTNYTNCARGCN AAYAAYCCNAAYGCNGARAARAAYGAYACNACNGGNYTNGARGGNGTNGARMGNMGNTGG GCNGCNTTYAAYGGNGGNGTNGGNGARAARCARYTNGARTGGYTNGCNCARGTNYTNGAR AARGCNCARAARAARGGNGARAAYGTNATHATHTCNTCNCAYGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GTNYTNAARTAY TGGACNCARMGNTTYYTNGCNCAYAARATHAGYGAYGCNGARTCNAGYGCNGARTAYATH GCNGCNCAYGTNYTNGGNAARAARACNYTNCAYTGYGTNAAYCCNAARGARTAYAAYATH AAYCARCAYGARYTNGCNTCNATHAAYAARYTNTGYGARATGMGNCARACNMGNATHCCN GTNCARTAYATHATHGGNGARTGGGAYTTYGAYAARYTNACNYTNAARATGMGNMGNCCN GTNYTNATHCCNMGNCCNGARACNGARGARYTNGTNGCNTAYTGYTCNAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GGNTCNCCNGARGTNGGNGCNGTNAAYTTYAAYGTNYTNCAYACN YTNYTNCAYGCNATGATHCARAARYTNAAYYTNCARGARGTNAARGCNGAYATHGAYGAR CAYGAYMGNGARTTYYTNTCNACNCAYTCNGTNCCNMGNGCNTTYTCNGCNTTYAGYGTN GGNGARGAYTCNYTNTCNGARGAYAAYATHAGYGARAARTCNAGYTAYAAYGCNGCNAAY AARAGYCCNTTYCAYMGNYTNGARAARCARGTNTTYGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGTTYAARAAR ACNAARGCNAARATHYTNCARAAYGGNAGYMGNGARTCNGTNGAYAGYCARATHAGYAGY TCNAGYGCNAGYAAYGARAAYYTNTCNATHAGYACNAARGARAAYAARGAYACNAARGAY AARATHYTNCAYCARAARGTNCAYTTYCARGTNTAYTTYYTNGGNYTNGTNGCNGAYATH AAYTTYACNAAYTCNAARAARMGNGAYACNGARGCNCARYTNATHGAYATHGTNGARGAR TAYCARATHGAYGGNAARYTNCARGTNACNGCNACNGAYGARAAYAARGTNGTNATGAAY ATHTCNMGNCAYGGNATHAARGTNYTNGAYATHGCNGGNAARGARGTNYTNCARMGNCAY CCNYTNCAYACNATHGCNCARYTNACNCARTAYAAYGAYGGNTTYGGNMGNCARAAYATH TCNGTNAARATHGGNCARGTNGGNAARACNGTNTAYCAYTGYTAYGTNTTYCARTGYCAY TCNGARTGYTCNATH--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNGAYGARGCNACNYTNGCNMGNMGNGARAARCARATHCARTAYGGNAARGCNACN TAYTCNTAYAARATGTAYACNGARACNGTNAARMGNAAYGARMGNATHCCNGAYMGNAAR GCNCAYCCNMGNACNCCNGTNAARTCNCARAARTGYAGYMGNMGNAAYTGGGAYGCNCAR ATHAARGCNTGGAARAARTAYGTNCAYCARTGGGCNCAYGCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNGARTCNGTNTGYCAYGARYTNGAYGTNTCN GAYATHATHATHCCNCCNCCNATHAARACNGARGAYGTNCCNYTNCCNCCNGGNAGYCCN AARGAYAARGCNAAYGAYTCNCARGAYGCNGARACN---------GARGAYYTNGCNAAR ATHYTNYTNCCNNNNNNNNNNCCNNNNNNNNNNNNNAANAANNNNGAR---ACNYTNGAR YTNGGNAARGGNACNGTNTTYTTYTCNTTYAAYAAR---AARAGYAARATHGCNACNATG TCNGCNTTYAAYCARGARGARCCNGAYGCNGTNGARGTNCCNCCNAGYMGNCCNYTNACN GTNATGGAYAGYATHGARGARGARAARAARYTNATGAGYYTNGARGCNAGYYTNGAYGGN CARTCNACNAGYGAR--------------------------------------------- ---GCNAGYACNACNAGYTCNAAYYTNCCNAARCCNMGNYTNYTNGARGAYTTYGTNCAR GTNACNYTNATGAARGARGGNGCNGGNGAYATHTCNTGGCCNGCNGARACNATHAARTAY ACNAAYACNYTNCCNAGYATHCAYTAYGCNTGYAAYCCNATGCARTTYGAYTTYAARGAY ATHYTNACNGGNGGNGGN---------------GGNGGNGGNGGNGGNGGNGAYGCNGTN AARAARGARGARGARAAR------------CCNGARAARAAYGGNAARGARGTNAARCAR AARMGNAARCAY---TCNAGYMGNAARAARMGNMGNCAYMGNAARAGYGGNAARAARAAR GARGGNGARGGNAARGARGCNGARGGNGCNGARAARCARGCNGARGGNAARGARAAYGCN CCNCCNGGNGAYAARGGNGGNGARACNGAYAARAARGAYAARAARAARAARMGNAARAAR MGNMGNCAYAARAGYAGYAARAARACNGTNGARACNGGNAARGARGGNGARAARAARGAR GGNGARGARAAYGARGTNAGYAARTCNCAYMGNMGNTCNCAYMGNAARMGNACNMGNAAR GARMGNGAYGARTCNGCN---AARGGNGAYGTNGARGGNGARGARAARGGNGARGARAAY GCNGARGTNGCNGTNAAYGGNAARCCNAGYACN---------TCNTCNCARAARAGYAAR CAYAARCAYAARMGNAARCAYMGNMGNMGNMGNGGNGARMGNTCNGARAARGCNAARGCN ATGAGYGCNTCNGARAARGCNAARGTNGARAARAGYTCNGARGCNGTNAAYGCNAAYGAR CCNAARGTNAARATHGAYTAYTAYGARGARGAYGAYATGCAYATHCCNAGYGAYAAYGAR GTNGAYAARGARGGNGARCCNAARATHAARMGNCCNTAYMGNTCNAARAARMGNCAYAAY CCNGGNGARGGNAGYGARACNAAR---GCNGARAAYCARGTNYTNGGNAAYGARACNAGY GTNGAY------------------------------------------------------ ------------YTNAARATGCARAAYCCNACNGARYTN---------------TCNGAY AAYYTNAARGARGTNGCNCAYGGNAARGTNYTNAAYGGNGAYATHAAYGGNGGNMGNAAR MGNGGNACNAGYCAYTCNAGYGCNGAYGGNGCNACNCCNGCNAARGTNAAYAARAAYGAR AAR---GAYAARCARGARGAYACNTGGAGYAARATGGARGGNYTNTAYGARAAYAARGGN GARGARGGNTCNAARAGYAARTGGGAYACNAGYGAYAGYGARGGNGARGAYGTNYTNCAR AARACNYTNGAYGCNAAYGCN------------AAYGARGARGAYAARAGYGARATHAAR YTNYTNCARAARCCNACNAAYGGNAARATHCCNYTNACNAARACNATHYTNGARACNAAY ---------GGNTTYGGNCAYYTNAARCAY------------------------------ ---CAYATHTCNTCNYTNCCNATHAAYAGYAAYCAYATHAARCARGAYAAYGCNGAY--- YTNGTNAARAAYGARAARGGNGARGARGGNGARGARAGYAARAGYCARMGNGARGGNMGN GCNAARAARMGN---AGYMGNAARACNTAYTCNTCNTCNGARTAYTCNTCNCAYTCNMGN TCNTAYTCNMGNTCNMGNTCNGGNTCNTAYMGNAGYTAYTCNGAYGAYTCNMGNTAYAGY GAYTCNAGYMGNTCNCAYAGYMGNTCNTCNMGNAGYTAYAGYMGNAGYMGNTCNMGNMGN MGN------TAYMGNMGNMGNTCNTCNTCNAGYMGNGGNMGNAGYTAYAGYTAYAGYAGY MGNAGYAGYTCNAGYMGNTTYMGNTCNMGNTCNTAYTCNMGNTCNMGNAGYTAYTCNMGN TCNMGNTCNMGNAAYMGN---AAYTAYCAYAGYYTNTCNMGNAGYCCNTCNAARMGNMGN AGYACNAARYTNAARMGNATHYTNAARTCNCCNGCNATHACNCCNGCNGTNACNACNYTN ATHGTNGCNCCNGTNACNGGNTGYACN--------------------------------- ---------------ACNGGNGGNGGNGCNGCNGCNCCNGAYGAYATHCCNYTNCCNGGN TCNTCNACNCCNAAYTCNTCNTCNAAYAAYACNGTNACNAGYCCNAARCARGAYCARTCN ACNYTNACNGAYATHCCNYTNCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARACNGTNTTYGAYACNMGNTGG CARTTYTCNGGNACNTTYTCNMGNGAYGGNGGNATHYTNCARMGNGAYAAYTCNGAYGTN GTNYTNGTNGTNGGNMGNGAYGCNGTNCARCARMGNGARYTNGTNCAYATHCARGGNGCN ATHTTYACNGAYGCNTCNCARATHAARACNAARTTYGGNYTNCCNAGYAGYGARATGATG ATHACNCCNGTNGTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGGAR GCNGCNAARATHTCNMGNYTNMGNGAYGARCARGARAARGCNTTYGCNGARACNCARGAR CARGTNAAYAARTTYGARAARTTYMGNTCNGAYTAYAARGCNYTNCARACNMGNYTNMGN ACNYTNCCNGARGARYTNTCNCAYGAYGTNATGGTNCCNTTYGGNAARYTNGCNTTYATG CCNGGNAARATHGTNAARACNAAYGARATHYTNGTNYTNYTNGGNGAYAAYTGGTTYGCN GARMGNTCNGCNAARCARGCNMGNGARATHGCNGGNMGNMGNATHGCNGARYTNGAYAAR MGNATHCARTCNYTNAARGARCARCARAAYYTNYTNGGNTCNMGNYTNGGNTTYACNTCN GARYTNCARGAYATGGCNGARGGNAARGGNGAYTGYAARGARATHATHGARGARTAYGAY GARGARAARGARMGNYTNTGGGAYGARCARCAYAARAARAAYGTNMGNMGN------TAY CAYGARAARYTNAARAARGARAARAAYACNTCNATHTCNATGAAYGARCARGGNGARAAY AAYGCNGTNAGYGARGAYAAYGTNTGGGCNMGNYTNGARGCNYTNGARAARCARGARAAY GARMGNGGNGARYTNGARAGYTCNTTYGAYGAYTCNGAYGAYGARMGNGGNCARYTNTCN ACNAARYTNGAYACNTCNCCNCARAAYATGAARMGNGTNGTNTGGGARGAYGARGGNGCN AARMGN---------------------AARGAYGARAGYGARACNGCNGARTAYTCNGAR ------GAYAGYGAYGAYGAYGAYGARTAYGARGARGARGAYGAYGAYGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AAYTGYTCNCAYYTNGARYTNACN GCNGTNCCNATHAAYYTNMGNAARGAYGTNGARGGNYTNGAYYTNTCNCAYAAYYTNATH TCNCARYTNCAYAAYAGYCCNTTYAARGTNTAYTCNAARYTNAARTAYGTNTCNYTNCAR CAYAAYAAYYTNACNMGNYTNGARATHGAYTCNTTYCARGGNYTNGARCAYYTNCARGCN YTNGAYYTNTAYCAYAAYCARYTNGTNATGAAYGARGGNACNTTYCCNMGNGGNGTNTTY MGNAAYYTNAGYGAYYTNGTNGCNTTYCARTTYAAYMGNAAYACNMGNTAYCCNGARCAR TCNGGNYTNTTYTAYCCNGAYCARGCNYTNGCNGAYYTNAARTCNYTNMGNTTYYTNTCN ATGGAYGGNYTNACNAAYAARACNTTYGAYAARGGNTTYGGNAAYYTNACNACNYTNGAR ACNYTNTCNYTNTCNGGNTAYAAYACNGGNTAYTGYGARYTNMGNTGYYTNTCNAARAAY TCNTTYAARTAYYTNGARTCNYTNAARATGYTNGAYATHAGYGAYTGYGGNYTNGAYGGN GAYTGYTTYGAYYTNCARGCNYTNTCNCCNYTNCARAAYYTNCARACNYTNTAYYTNAAY TGGAAYCARTTYYTNTCNTTYAARACNYTNACNAARGTNATHAARCCNYTNAAYCARTCN GGNAAYYTNAARGARYTNTTYATHGGNMGNATHGARCAYCARTAYCARCCNGGNGTNATG ATHAARAARTCNTAYGTNCARAGYYTNCCNTCNAGYYTNYTNTGYYTNGTNGCNAAYGGN AAYAGYATHAAYGAYGTNGARAAYGGNGTNYTNTCNGARYTNCCNAARTCNATHAARTAY YTNGAYTTYTCNGGNAAYAARATGGTNTTYGGNAAYTAYYTNAARAAYYTNACNGTNYTN ACNAAYYTNAARTTYYTNAARYTNAAYGGNMGNGARTAYYTNTTYMGNGTNCCNATHATG TAYCCNMGNCARGARAAYGARGAYAAYTTY---MGNCAYCCNGARAAYGGNGTNGAYMGN TAYCAYGTNGAYAARCARCARCARGAYATGATHYTNTTYYTNCCNCCNAAYYTNAARMGN YTNACNATGAARTAYGCNGGNYTNTGGTAYATHATGACNACNYTNCAYGTNAAYGARAGY AAYACNYTNGARGARYTNGAYATHAGYTTYAAYTAYTTYCCNTCNYTNAARGGNCCNTTY ACNGGNYTNMGNMGNYTNAARAARYTNGTNATGYTNAGYTGYMGNATHGARTTYATGCAY AAYACNTTYTTYGARCAYTTYCCNGCNYTNGARTAYYTNGAYYTNAGYGGNAAYYTNATH GGNGGNGTNAAYAGYYTNTCNYTNTCNMGNCARCCNTTYAARCAYYTNAARAGYYTNGAY ATHYTNAAYATGACNTTYAAYAAYATHTTYAAYATGAARCCNGAYTCNTTYACNGGNYTN GCNATGYTNMGNGARYTNCAYYTNGGNGARAAYCCNTTYTTYGTNTTYAAYGCNAGYATH TCNCAYATGAAYGAYYTNMGNATHYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNMGNTTYTCNGTNYTNCCNAAYACNMGN AARGTNTCNAAYGGNGAYATHMGNACNMGNAARACNACNYTNATGYTNTTYATHATHTCN GCNGTNTTYGTNGCNAGYTTYYTNCCNTAYYTNATHTTYAARGCNYTNCARGCNATHAAR AARGAYTTYCCNCCNAGYGAYTCNAAYAGYCARATHATHYTNTAYAAYATHTTYGTNMGN TCNTAYTTYTTYAAYAGYGTNGCNAAYGGNTTYATHTAYGGNTTYTGYAGYGCNAAR--- ------------------------GAYGTNGTNATHGGNTTYCAYGARAAYGAYTTYAAR TTYGTNGARMGNYTNGCNGAYAARTTYAAYTCNTCNGGNYTNAGYGTNTGGTAY---AAY CARACNATHGAYGGNAARAARACNAGYGARGCNATHYTNGGNTGYAARGTNTAYYTNCCN GTNYTNACNGARATHTCNGCNCCNGAYAARGGNATHCAYGARCARYTNTCNYTNGCNTAY ATHTCNAAYTCNGCNATHTAYCCNYTNGCNMGNATHCCNTTYCAYAARYTNGCNACNAAR YTNAAYGGNGGNGCNMGNYTNATGYTNGCNAARATHAAYTGGTCNTTYATHTTYAARGAY GARCAYTTYGARGARMGNACNGAYACNATHATHGARTGYATHAARAARGAYATHAARAAY ATH---------------GARAARATHACNCAYCARGAYTAYGCNACNACNCAYGGN--- ---ATGMGNATHCCNYTNTCNCAYYTNCCNAAYATGGARGAYGGNGARCARGARTTYGTN TCNTTYAAYCARGGNATHGAYYTNAGYGTNATHAGYAARGAYACNCCNTTYTGGGAYMGN CAYTTYATGGGNAARAGYGARGTNGCNTGGGTNGAYTTYMGNGARAARTTYYTNMGNGAY TAYGGNGARAARATHATHGARGGNTTYTCNGARGGNGTNGARGARMGNAARAAYYTNTTY ATHAAYYTNATGTTYAARGAYGTNYTNAARGGNMGNAARATHGTNCARMGNTCNGARTAY GAYAAYTTYTGYGAYAARTCNCAYCCNCAYGCNTTYTTYACNGGNATGGARGARTAYGTN YTNGCNTAYTCNTCNYTNMGNGARGTNYTNAGYATGGAYAGYAGYYTNMGNATHTCNACN ATHCARAAYYTNGGNMGNTAYCARTTYCCNGTNATHGTNTCNGGNYTNTCNGAYATGYTN AARGAYGAYGAYCCNAAYGTNMGNGCNGTNGCNGCNATHGCNYTNGCNCAYGCNGGNAAR ATGAARGAYTCNACNGTNGAYAARATHATHCCNYTNYTNGARGAYGARGAYMGNYTNGTN MGNGARAGYGCNTGYYTNAGYYTNGGNTTYYTNMGNTCNGCNMGNGCNGTNYTNTAYGTN GTNGAYMGNTGGMGNAAYGAYCCNATHTCNACNGTNMGNGARGCNGCNGARYTNGCNYTN AGYMGNATGGAYGCNCCNGAYGCNGTNCARTGYATGAARGTNACNAARGTNYTNTCNTCN GARATGAAYGCNYTNAARCCNTCNGCNTTYAAYATHGAYYTNAARACNGCNYTNGTNCAY GARGGNTCNAAYGGNAGYATGTTYGGNTAYTCNGTNGCNCARCAYGTNGAYCARGGNGTN CAYTGGYTNYTNATHGGNGCNCCNAARTTYCARACNMGNCARMGNGAYYTNGTNAAYCCN GGNGCNGTNTTYMGNTGYAARACNGAYMGNGTNTTYTCNTGYCARCARATGCCNTTYGAY AAYACNGGNAAYAAYATHAAYTAYAAYMGNAARYTNCARCARTAYYTNCCNATHGARGAR AARTCNAAYCARTGGTTYGGNGCNACNATHGARAGYTCNGGNGARAAYGGNGTNGTNGTN GCNTGYGCNCCNMGNTAYGTNTAYTTYGGNCCNAAYTCNGAYAARMGNGARCCNGTNGGN ATGTGYTGGGTNGCNAARACNTCNACNACNGARTAYGARMGNTAYTCNCCNTGY------ ---------------------------------------------YTNGARMGNAARGAR MGNYTNACNGARATGAAYGARGARGARTGYCARGAYGTNAARAAYGARAARAARTCNYTN GARAARGARATHAARAARTAYMGNAGYGAYYTNAARGGNYTNMGNTGGCARAAYTGGAAR AGYATGATHATGTCNATHAGYYTNTTYGGNTTYTTYTAYATHGTNTAYATHYTNYTNTTY GAYTCNGAYTCN---------------------ATGGAYACNTAYGTNCCNAGYCCNAAY YTNATHAAYGCNACNTTYTCNCCNATHCCNAAYTCN------ATHTAYGAYCARGAYAAR YTNGARGTNTTY---TCNTGYAAYTCNAARATGAAYGTNAAYAAYGAYGAYTCNGAYGTN TGYGGNTCNTAYGARGARACNCAYTCNYTNGAYGGNAAYYTNGARGAYAGYTCNYTNAAR AAYATHYTNACNTCNGARYTNYTNAAYTCNATHTCNAGYTCNTCNGGNGGNYTNGCNCAR ACNAAYYTNTGGGGNAAYAAYAARTCNAAYATHGTNGAYTTYCARGAYACNTCNATGATG GAYCARCCNTTYCCN------------ATHGCNATGGARTCNGAYYTN------YTNTCN GAYYTNYTNAAYATHGAYTCNAAYGAYAAY------TTYGAYTTYGAYTTYATGACNAGY AAYCCNTCNTCNTCNTGYCARACNCCNGTNCCNTCNGTNTCN------------------ ---------------GARTCNAARGTNGAYATHCARGARYTNCCNCCNATGGAYMGNATH TCNMGNAGYAAYAARGAYGTNACNATHTCNAGYTCNAAYGTNACNTCNGAYAAYATHGGN CARGGNTTYATHYTNAARMGNTTYAAYTTYCCNCCNMGNAARTCNGARCCNCCNGTNGGN ATHGTNACNCCNGTNAARGTNGARGARAGYGARGGNTAYYTNATGCARMGNTCNTCNCAR ---------------------------ACNGTNGARMGNGGNYTNAARAARGARGGNAAY MGN---------------GCNAGYCAYCCNYTNGCNGARCAYCCNCARACNGTNCCNYTN TTYNNNTTYTCNGAYCAYGCNGAR---------CAYGARACNACNNNNNNNAARMGNGAR TTYACNACNNNNGTN--------------------------------------------- ------------ATHGARGAYAARTGGGAYGARATGAAR------YTNTCNGAYCARTCN TCNYTNTGYCARCCNAARMGNMGNMGNTAYGAYTCNGGNAGYTCNTGGCARACNTCNGAR GAY---GGNGAYGARNNNNNNNNNNNNNNNNNNNNNNNNAAYGAYTAYGAYTCNGAYGAY GAYAAYTCNGAYYTNGAYGCNGAYYTNGCNCAYYTNAARCCNGGNAAYTGYGARTCNYTN ATHGAYTGYGGNAARAARCARAARCARTAYTTYTGGCARTAYAAYGTNCARGCNAARGGN CCNAARGGNACNMGNYTNAARYTNYTNGTNGAYTCNCCNTCNGAYCCNCAYATHYTNAAY GAYTTYGARGAYCCNGTNTTYGAYGARGGNAAYACNATHGTNGCNGGNATHMGNCAYGGN GGNAARGCNMGNAARGGNGAYGGNAAYGARGTNACNCCNAAYCCNYTNAARYTNTTYAAR ATHGGNCAYCARYTNYTNMGNYTNAAYAARAARATHAAYGGNTGYCARYTNGGNTCNGAY GTNCCNYTNACNCARMGNAAYGARGCNMGNMGNGARAARAAYAARYTNGCNTCNMGNGCN TGYMGNYTNAARAARAARGCNCARCAYGARGCNAAYAARATHAARYTNMGNGGNYTNGAR ACNGARCAYGGNCARATHAAYAGYGTNYTNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TAYMGNGAYYTNGTNATHAAYGARTCNGARMGNYTNTCNAGYYTN TGYAARACNTGGAAYGAYGTNGCNGCNMGNGARGCNGAYYTNAGYGARGARGTNYTNGGN CARATHMGNTCNACNGTNGGNAARGCNYTNYTNYTNATGGARCARMGNTTYAARCARTTY TCNGGNYTNGTNGAYAAYTAYGTNTAYGAYYTNGGNGARAARAARACNACNCCNACNGAY YTNCARGGNTTYTGGGARATGATHTAYTAYCARGTNGARGAYGTNGAYGCNYTNTTYAAR GGNYTNGARCARYTNCARCARTCNAAYTGGCARACNAARATHGARTCNCCNAARATHACN GGN------CCNAARAARMGNATHGCNAARGTNAARCCNMGNGTNAAR------------ ------------------------------------------------------------ ---------------ATGGAYGARYTNAARAARYTNAARGTNCCNGARYTNMGNGAYGCN YTNAARGTNAARGGNYTNCCNACNTCNGGNACNAARCARGARYTNATHAAYMGNYTNATH GARGCN---------------------TCNAAYGGNACNGCNCARAAYGAYTCNGCNATH GAYGARGAYGARATHYTNAARGAYGAY---------------------------AGYGTN ACNGARGCNGTNGTNGTNCCNCCNAARACNACNYTNCCNTCNTCNACNGARCARTCNCAY AAYAAYAAYAAYAAYGGNATHGARGCNATHAGYGARAGYTCNGARYTNCCNACNACN--- ------TCNAGYTCNTCNGAYGCNAARYTNGCNAARCCNGCNGARGTNAARACNYTNACN GARGCNGARMGNYTNCARATGMGNGCNGAYAARTTYGGNGTNACNTCNGARAARGCNAAR AARGARATHMGNGCNCARMGNTTYGGNATHGCNGARAGYAARTCN------GGNAAYATH TCNACNAAYGTNCCNCCNGCNGAYYTNCARAARYTNCARAARMGNGCNGAYMGNTTYGGN ATH------------TCNACNAGYTCNGTNACNGARGAYGARAARAARMGNAARMGNGCN GARMGNTTYGGNATHAGYYTNTCNACNCCNTCN---------ACNTCNACNAARGGNTTY ACNGAYAGYGARYTNGARGCNAARAARMGNAARMGNGCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNCCNAARYTNAAYCAYGCNGTNGTNTTYTGYGAYGCNAARATGGCN GARGTNYTNCAYTGGGTNGGNGGNATGGCNACNYTNYTNCARGCNGGNGCNAGYGAYGTN MGNGARTTYTCNTCNTTYGARAGYGGNAAYGARGAYCARAARAARGCNGTNTTYYTNYTN AGYMGNTGYYTNGARGGNGTNACNGARCARATHYTNCARGAYATHGTNACNCARAGYTCN TTYCARTAYGTNATHGTNTTYACNTCNGCNCAYCCNATGYTNCAYTCNGARGTNTCNYTN AGYAAYGTNGARAAYGGNACNGCNTTYGAYCCNTTYGARGARYTNATHYTNGARTGGATG GGNAAYATGAAYTAYACNGTNGARATHGARCAYGTNAGYYTNTTYGCNACNGARGTNTCN CCNGGNTTYTTYATHACNCCNGGNTTYGCNGARYTNTTYCCNYTNYTNTCNTCNGAYYTN CARCARATHAAYTAYCARCAYAGYYTNAARMGN---CCNAARGARGCNAARAGYTGYGAY AAYATHAAYGARYTNGAYATHACNCARYTNCCNGCNGARYTNGARYTNCARATHMGNTCN TTYTCNACNTCNYTNGAYGGNYTNTTYCARGCNATGAAYGTNAARGARGAYATHTAYTCN ATHGGNAGYYTNAGYMGNATHATHGCNACNGAYYTNGAYAAYTTYCCNYTNGCNAARGCN MGNMGNAARGTNTGYCARTCNMGNYTNTCNYTNGTNYTNGTNGAYMGNACNYTNGAYATH GCNTCNGCNGTNACNACNCARTTYGAYAAYYTNYTNGAYAARGTNGTNAAYTGYYTNCCN TGYYTNGAYGGNCAYACNATHGAYMGNMGNGTNGAYATGTCNGAYYTNTGYCAYTGY--- ---TAYAARTCNAAYTCNAGYATHGCNYTNCCNGGNTGYYTNGCNCCNAGYAARYTNACN GARTCNCCNCAYCAYYTNTCNGCNTGYATHYTNAARAARCARAARGARGCNYTNATGGAY ATHAAYMGNAARYTNGTNGARACNGCNGCNGCNGARAARYTNCCNYTNGAYYTNTCNMGN AARCCNAGYMGNGTNACNGCNGARYTNYTNGAYTCNACNYTNGCNYTNTTYAARGGNAAR TAYTCNYTNATHGGNAARCAYYTNGARACNYTNGARATHGCNATGGCNACNAGYCARGCN YTNAARGAYAARAGYGCNCAYCAYCAYGAYAAYYTNGTNGCNAARGARAARAAYATHGTN CARTCNYTNGCNGAYACN------------------GAR---------------CARGGN GAYGARGARCCNTCNGCNTTYACNYTNYTNTCNAARYTNATHGTNGARGARYTNGARAAR AGYGAYGARGARMGNGARTTYACNACNGAYGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGYTNMGNGCN GCNYTNAARACNAGYGAYTGGATHAARATGGAYACNTGGGARTGYGARCARACNTCNTGG CARGARACNATHAARGTNYTNMGNCAYGTNAARCARYTNYTNGARGTNCARTAY------ GGNGCNCCNGCNMGNCCNTCNAARMGNMGNAARAARCARCARGTNTCNGAYYTNACNCAR AAYMGNGTNCCNMGNATHGAYGTNGARGARGARCARGTNCCNYTNGTNMGNYTNYTNTGY GGNGCNGAYYTNYTNGARTCNTTYGCNGTNCCNGGNYTNTGGAARGARGARGAYATHGAR CARATHGTNTCNAAYCAYGGNYTNGTNGTNATHAAYMGNCARGGNTCNGAYGCNGCNAAR TTYGTNTAYGARTCNGAYGTNYTNTCNAARTAYMGNGARAAYATHATGYTNGTNACNGAR TGGYTNCARAAYGAYATHAGYTCNACNAARATHMGNMGNGCNTGYMGNMGNGGNGARAGY ATHAARTAYGTNGTNCARGAYGCNGTNATHGAYTAYATHAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GTNCCN TGYATHTCNTTYATHAARYTNAARATHATHTTYGCNAARMGNTGYGTNCARYTNAARMGN TAYCARGARGCNGCNGARCARTAYTCNAGYYTNATHAARATGATHCARGAYGARGAYTAY TTYGCNCAYGARAAYAARGAYCARATHGAY------------GTNGTNGARATHYTNGTN GARGCNGCNGARGTNYTNYTNATHACNCARCARTTYCARGAYTGYATHMGNYTNTGYAAY CARGCNCARCCNYTNYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNTGYGTNGAYAAYGAR TGGACNTCNGGNAAYTAYCCNCAYCCNACNMGNTGYGAYMGNTTYATHGARTGYGCNAAY GGNATHACNAAYATHATGATGTGYCCNCARCCNYTNGCNTAYAAYCCNGCNYTNGAYGAR TGYGAYGAYCCNACNAARGTNACNAAYTGYCAYTTYGGNTCNTCNACNCCNTCNATHGAY CCNYTNACNGTNTGYMGNGAYYTNAARYTNACNCARGGNATHCAYCCNCAYCCNACNAAR TGYGAYCAYTTYATHGARTGYACNGCNGAYGTNACNACNCCNGARCCNTGYCCNGCNGGN YTNCAYTAYAGYGTNATHGARCARGCNTGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TTYTTYYTNAGYTGYAARTCNGTNYTNGCNYTNGAYGGNMGNGTNYTNGTNACNYTNTGY AARGGNCARGGNGGNACNCCNGCNGAYCARCCNATHMGNTCNTGGCAYGAYAGYTGGCAR ATHGTNGCNATGGCNACNAAYGCNAGYTTYYTNYTNTGYCARGTNTCNCCNTTYGAYCCN TCNGARTTYCCNGARTAYCAYAGYGTNGGNTTYMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AGYTGYMGNATHAARGCNMGNYTNGTNTTYAGYTGYATHGGNATHYTNGTNGGNTTYTCN GCNGGNGCNGCNTTYACNGTNCAYTTYAARAAYTAYAAYGCNGGNATHTGGGGNATHTGY TCNGGNATHGCNGCNYTNGTNGCNYTNTGYGTNACNGTNGCNTTYATHMGNMGNGGNTGG GAYGCNAAYCCNATGMGNYTNAARCAYTTYATGYTNGCNGGNTGYTTYATHCARYTNGCN GGNGTNTGYGGNTTYGTNGCNTAYATHGTNYTNGCNATHTCNAARGARCARGGNYTNGAY GCNTAYGGNCARGGNTTYTAYGTNGCNTCNGTNTGGTGYTTYATGACNTGGAARTGG--- ------------------------------------------ATGAGYCAYGGNGAYCCN ACNTCNTAYTCNGARCCNGARAARTGYGARATGAARMGNYTNAAYTGGAAYGTNAARYTN GAYTTYAAYTCNCAYACNATHCAYGGNATHGCNAGYYTNTAYTTYGARAARAARACNGAY GARYTNAAYACNYTNYTNYTNGAYATHMGNGAYYTNAGYATHGARGTNGTNAARYTNCAR GGNCAYGAYCARAAYYTNAARTTYGGNGTNGAYAAYCCNGCNGGNGTNGAYTAYGGNTCN MGNYTNTCNATHGARYTNCCNACNATHCCNACNGARAGYTTYACNYTNGAYATHACNTAY TCNACNTCNAARTCNTCNACNGCNYTNCARTGGATGACNCCNGARCARACNGCNGGNAAR MGNCARCCNTAYYTNTAYAGYCARTGYCARGCNATHCAYGCNMGNAGYYTNTAYCCNTGY CARGAYACNCCNGCNGTNMGNTTYACNTAYAARGCNCARGTNGARGCNCCNAARGARATH ACNGTNYTNATGAGYGCNAAYMGN---------GGNGARGTNATHTCNAARCARGAYACN ACNGTNACNCAYTTYACNYTNGAYATHCCNATHCCNAGYTAYYTNYTNGCNATHGTNGCN GGNGAYYTNGARTCNMGNGAYATHGGNCCNMGNTCNAARGTNTGGTCNGARMGNGARATG GTNGARGCNGCNGCNTAYGARTTYGCNGARACNGARTCNATGYTNCARACNGCNGARGAY YTNATGGGNCCNTAYYTNTGGGGNCARTAYGAYYTNYTNGTNYTNCCNCCNTCNTTYCCN TAYGGNGGNATGGARAAYCCNTGYYTNACNTTYGTNACNCCNACNYTNYTNGCNGGNGAY MGNTCNYTNGTNAAYGTNGTNGCNCAYGARATHTCNCAYAGYTGGACNGGNAAYYTNGTN ACNAAYGCNAAYTTYGARCAYTTYTGGYTNAAYGARGGNCAYACNGTNTTYTTYGARMGN AARATHCAYTCNAARYTNTAYGGNGARTCNATG---MGNCARYTNCAYGCNCAYGAYGGN TGGYTNACNYTNAAYAARACNGTNAARCARYTNACNGARGAYGGNCAYGCNCCNTAYACN AARYTNGTNCCNGARYTNTGYGGNGTNGAYCCNGAYGARGCNTTYTCNAGYGTNCCNTAY GARAARGGNTTYGCNYTNYTNGARCAYYTNGARMGNATGYTNGGNGGNCCNGAYGTNTTY AAYAARTTYYTNMGNGARTAYATHGARCAYTTYAARTTYAARTCNATHMGNACNCARGAY TGGAARGARTTYYTNTTYAGYTTYTTYTCNTCNCCNGARGAYCARAARAARYTNACNAGY ATHGAYTGGGAYAARTGGYTNTAYGGNGARGGNYTNCCNCCNTTYACNCCNAAYTAYGAY YTNAGYYTNGCNGARGCNAGYCAYAAYYTNAGYCARMGNTGGATHAGYGCNTCNGAYGAY ------GARAGYTTYTCNGCNGCNGAYATHAARGAYATGAAYAGYGAYYTNATHAAYGAY TTYYTNTCNTCNGTNTCNYTNGCNAARMGNCCNGTNTCNYTNAGYAARGTNCARAARATG GARGARGTNTAYCAYTTYAAYGCNGTNAARAAYTCNGARATHMGNTTYACNTGGYTNCAR YTNTGYATHCARTCNCARTGGAAYGARGCNATHGARCAYATHATHAAYTTYATHAAYGAR CARGGNMGNATGAARTTYGTNGTNCCNYTNTAYMGNTCNATGAGYAARTGGGARGARGGN MGNAARCAYGCNTGGAARAAYTTYATGGCNCAYAARGCNGARATGCAYAGYACNACNGCN AARAARGTNGAR---ATGTCNYTNGAYTAYMGNGAYAGYGARMGNMGNMGNYTNAAYGAY TTYCARTCNMGNGARAARGARATHGCNGCNGTNAARGTNGCNTCNCCNGCNTCNCCNAAR TCNCARCARCARAAYGAYAARMGNGTNMGNMGNGARATHGCNAAYGGNAAYGARMGNMGN MGNATGCARTGYATHAAYGCNGGNTTYAAYTCNYTNMGNGCNYTNATHCCNCAYYTNGAR GGNGARAARYTNAGYAARGCNTCNATHYTNCARCARAGYATHGAYCAYATHACNAGYYTN GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGAYAAYCARGAR GARATHYTNGAYGCNYTNACNGCNYTNGGNAARAAYCCNAGYCCNCARGARATHCCNCCN ATHYTNGARCARTAYYTNMGNTCNGTNGCNAARAGYGGNGARACNTTYTTYCCNTGGTCN CARYTNAARCCNYTNATHYTNMGNAARATGGARYTNGTNATHYTNGARYTNMGNMGNAAY YTNGCNTCNGARAAYATHCCNACNMGNCCNAAYGTNGARAAYGTNMGNTTYGAYGTNATG CAYGCNMGNATHATHGAYGCNYTNCAYAARTTYAAYGGNGCNCCNTTYACNATHCARMGN YTNTGYGARYTNYTNATHGARCCNAARMGNCAYTAYAARMGNAGYGAYAARTAYATGMGN GGNYTNGARAARAAYGTNYTNGTNGTNAGYACNGTNGAYCCNTTYGGNMGNAARGTNGTN TGYGARTCNGGNAGYAARCCNGTNYTNAAYGGNGTNYTN---GAYGTNAAYGGNTCNTAY YTNTCN---MGNGAYGGNGGNYTNAGYGTNCCNYTNCCNCCNGTNCCNGGNTGGGTNAAY ACNCCNGGNTCNACNTCNGCNACNAAYGGNGCNACNTCNAAYAAYCAYACNAARGGNYTN CCNGGNACNACNAARTCNCARAGYCCNGARACNGAYGGNGARGTNTCNAAYAGY------ ------------------GARTCNGTNTTYGCNCCNCARGGNGAY---GCNYTNCCNATH CARTCNGARGARGTNATHGARGARACNGTNGTNACNATGGAYACNGGNGAR--------- GTNGGNGCNGAYGCNGGNGARGCNATGGCNGAYMGNGARGGNGARGAR---------ATG TCNGARGAYMGNGARGCNTCNTCNTTYTCNTCNTCNTCNTCNTCNTCNGARGARYTNTCN ACNTCNTCNGAYTCNGTNGARAAYATGMGNGTNTCNCCNTTYGGNGCNGARAAYGGNGTN AARGARGAYTCNGAYGARCARMGNCCNTGGGCNGCNTTYGCNCARCARTCNAARCARGAY TCNGAYGTN---ACNCAYTCNTTYTCNACNAAYAAYCARTCNAARGCNACNCCNGAYGGN ATHGARYTNTCNAGYGCNATHTCNTCNTCNYTNCCNGTNACNACNTCNTCNTCNCCNCCN TCNTCNTCNTCNCAYACNAARATG---------TCNATGACNGCNTCNTCNGARGCNGAY AAYGAYCARACNATHCAYCARGCNGAYGTNGCN------------CARTCNGAYCARTCN GTNATHGAYATHGCNGAY------------------------------------------ ------------------------CARAGYYTNGGNTTYGARCCNATHAAYCCNAGYGCN GAY--------------------------------------------------------- ------------------------------AAYGAYACNGCNATHAAYTTYTCNCCNGAR AARGARAARYTNGTNTCNTCNTCNTCNYTNTCNYTNACNTCNACNACNACNGCNAAYGTN ACNACNACNACNTCNACNTCNGTNACNGAYACNTCNACNCAYACNYTNCCNGCNTCNGAY TCNGCNATHGTNTCNTCNACNGGNCAYGTNGCN---YTNACNTAYGCNCARGTNGTNGCN TCNTCNAGYACNGAYAAYCARTCNTCNCARCCNAGYTCNGCNACNTGYGAYAGYGTNGCN GGNYTNGARMGNYTNGTNGGNTCNATGGARCCNACNGTNACNTCNCCNGARACNTCNTCN TCNYTNYTNTCNCARCCNATHGAYAGYACNAAYCCNAAYGCNAARATHACNCCNTCNYTN CCNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNGGNAAY------TCNACNGCNACNYTN GTNACNATGGTNACNGCNYTNCCNAAYTCNTCNAGYGGNACNACNACNAGYACNACNGAY GTNTCN------------------------GGNTCNAAYATGYTNTCNTTYCCNGTNGGN YTNAGYGGNYTNACNCARYTNATGCCNGTNACNTCNAARGGNCARGCNAGYCARAAYATH MGNTCNACNGCNATGCCNYTNYTNCARYTNCARGGNCARCARGGNATHCARYTNGTNAGY GTNCARCARMGNGGNCARAARCCNTCN---TCNAAYAGYTCNAGYCCNGGNCARGGNATH AAYMGNYTNGCNCAYGGNGGNACNTCNTCNGTNCCNYTNTCNACNGTNYTNGCNGGNCAR CARATGTCNGGNGTNGGNCARGGNGCNATHACNGCN------------------------ ---CARCARYTNATHCARYTNACN------------GGNTGYCARGGNTCNTCNTCNTCN CARMGNGCNGCNCAYATHACNTTYGGNAARGCNCARCARGGNYTNCARYTNCAYTCNYTN CARYTNAAYCARGCNGGNTCNAGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CARGAYCARYTNAAYGAYCARAAYGARCARTTYTTYTCNGCNTGYGAY GGNATHTTYYTNAAYTAYAAYATHTCNGARGARAARYTNAAYAAYTCNMGNGARYTNGCN TCNGCNTCNAAYMGNTGYACNGARGTNTAYGTNGGNGTNGAYGTNTTYGGNMGNAGYACN CCNGGNGGNGGNGGNTTYAAYTGYAARGARGCNYTNGARYTNATH--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TCNAGYCCNAARCCNGCNMGNGARAAYACNCCN GARAARAARGTNTCN------------AAYTCNAAYAARGARTCNCCNYTNAAYACNGAR AARTCNTCNGAYGAYAARGARAGYGCNTCNGAYGCNTCNAARCCNTCNTCNTCNCCNTCN TCNCAR------------TCNCCNTCNTCNGGNCCNTCN---TCNCARAARMGNAARCCN AGYGARGAYAGYGARGARATGAARCARGCNATHAARCAYYTNAARAARCARGAYGARGAR MGNATGAARATGCARGTNYTNGTNTCNAAYTTYTCNGARGARCARYTNAAYMGNTAYGAR ATGTAYMGNMGNGCNACNTTYCCNMGNGCNTCNATHAARMGNYTNATGCARAAYATHACN GGNACNACNGTNTCNCARAAYGTNGTNATHGCNATGTCNGGNATHGCNAARGTNTTYGTN GGNGARGTNYTNGARACNGCNYTNGAYGTNAGYGARAARTGGGARGAYTCNGGNCCNYTN CAYCCNAARCAYYTNMGNGARGCNGTNMGNGTNYTNCAYTCNAARGGNCARATGCCNTCN ACNAARAAYAARAARCAYYTNTTYTCNATH---ATGTCNGCNACNAARGTNCARGTNCCN AGYGCNAAYAARYTNGGNGCNATHCCNGCNATGGTNACNGGNGAYCCNGCNAARATGTCN MGNGGNYTNATHGTNYTNCARGARTGGTGGGGNYTNAAYGARCARATHCARGAYTGYGGN ATGGARYTNTCNTCNACNGGNAAR---YTNGTNACNGTNGTNCCNGAYYTNTAYMGNGGN AARGTNACNAARGAYAAYGARGARGCNGGNCAYTTYATGGGNGAYYTNGAYTGGAARGGN GCNATHGAYGAYATHCARGGNTGYGCNAARTAYYTNAARAGYAARGGNGTNAARAARGTN GCNGTNACNGGNTTYTGYATGGGNGGNGCNYTNTCNATGGCNGCNGCNGCNYTNGTNCCN GARATHGAYGTNGCNGTNCCNTTYTAYGGNATHCCNTCNCCNCARYTNTGYGAYGTNACN ACNATHAARATHCCNATGCARTGYCAYTTYGCNYTNCARGAYGCNACNGCNGGNTTYGCN TCNCCNGCNGARTGGMGNCCNYTNAARGARAARYTNGARAARTCNATGAARGTNYTNGAR TTYTAYGARTAYGAYGCNGGNCAYGCNTTYACNAAYAARTCNGGNCCNAAYTAYAAYAAR GAYYTNTGYGCNYTNGGNTTYTCNMGNATGTTYGCNTTYYTNGAYAARCAYATG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AARATHTCNGAY ACNGARYTNGCNAARGTNTGYCAYYTNATHGCNGARAGYTTYTAYCARGAYAARACNATH AARTCNGARCARYTNGTNGAYACNTGGTCNYTNGARGARTGGTGGGARGTNMGNGCNTTY YTNYTNCAYYTNATGAARCARGCNGTNMGNCARGARTGGAGYMGNGTNCARGTNTTYTCN GARYTNGGNCARGTNTCNGARTCNTAYAARAGYATHATHGCNGAYACNATHTCNGTNCAY CARAAYACNTTYAARCARAARYTNYTNCARAAYACNAGYTTYATHTCNCAYGCNGTNYTN TCNGAYTTYGAYTGGAARYTNCARYTNGCNYTNTCNAGYGAYAARATGTCNAGYYTNCAY CARCCNYTNGTNACNYTNGGNYTNGAYATHTGYCARGAYGGNGGNGARMGNAARCARGTN AGYYTNGARATGGAYMGNGCNGARYTNACNMGNYTNATHAAYTCNYTNGARAARTGYAGY AARACNGGNGCNAGYGTNATHGAYGAYGTNYTNAARGARGTNYTNGARTTYGCNGTNMGN GAYTAYATHAARACNTGGTAYAGYCARAARAGYGAYCAYGAYGGNTTYYTNGTNGAYATH TGGCARTGYGCNCARAARGTNATGATHACNTTYTCNAAYMGNTCNAARGARATHGAYTGG ACNCCNTAYTTYACNCARCAYYTN---TTYTCNGARGTNYTNGGNGARYTNGGNCARGAR GCNAARATGGTNATGYTNCARTAYTCNCARACNTTYAAYGARAGYGARYTNTAYGARCAR CARGGNYTNCARGCNATHTGYGAYYTNGCNGCNCAYGCNACNTGYYTNGARCARMGNYTN AARYTNCARAARGARYTNYTNTGYAAYMGNYTNCARGTNATHACNCARAAYYTNAARGTN GARYTN------------GGNCAYGGNACNGARGGNAARCCNYTNCARTTYTCNTCNGAR ATHCAYAAYAARGAYCAYATHYTNGARCAYYTNCARCAYGTNATHTCNACNAARCCNAAR GARCARATGACNGAYGARGARYTNGARTTYCAYTAYTTYAARYTNCAYGAYTAYGAYAAY AAYAAYAARYTNGAYGGNGTNGARATHGGNAARGCNYTNACNCAYTTYCAYGAYGAYTCN GGNTCNAAYGGN---------------AAYCARAAYAARGARCCNCCNAARGTNTTYTCN GAYGTNGARATHTCNAAYATHGTNGAYTCNGTNGTNGARGARAAYGAYAGYAAYAARGAY GGNTAYATHGARTAYTTYGARTTYAARACNAARCARGCNGARGCNAAR------------ ------------------CARCARGCNCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARTTYGCNGAYAGYYTNGCN TCNATHGARTCNGAYAARTTYGTNCCNGCNTCNTTYAARTCNTCN---ATHMGNGTNAAR YTNGAY---CCNGCNGARAARATHCARTCNAAYCAYGAYGAYGCNATHTTYGGNTCNYTN TCNACNAGYGGNTTYACNATHAARCCNGAYYTNGAYYTNAARCCNGTNGCNATGGAYGCN GARTCNGTNATGCAYCCNMGNYTNTTYTGYGAYGTNGARGARAARATGGARAARTGGATG GAYMGNYTNTCNCARYTNMGNMGNMGNAARYTNGARGGNGARGCNATHATGGAYGTNGTN GTNGTNGGNAGYTGYATGACNGAYYTNGTNAGYTAYGCNTCNMGNYTNCCNAARGARGGN GARACNYTNACNGGNCAYAARTTYACNGTNGGNTTYGGNGGNAARGGNGCNAAYCARTGY ATHACNGCNGTNMGNYTNGGNGCNAARGTNGCNATGGTNGGNAARYTNGGNGAYGAYACN TTYGGNAGYGAYTAYATGMGNAAYATGCARACNAAYGAYGTNAAYTGYGAYCAYYTNAAY TTYGTNCCNGGNGTNTCNAAYGGNGTNGCNTCNATHYTNGTNTCNGCNAAYGGNGCNAAY TGYATHGTNATHGTNCCNGGNGCNAAYAAYCAYYTNACNGTNGARGAYGTNCAYAAYGCN GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATGTCNTTYCCNGGNMGNGCNCCNATGGCNATGCCNGGN GGNATGCCNGGNATGGCNCCNMGNATGATG---GCNCCNGGNTAYGCNTTYACNTCNATG GGNATGACNMGNATGAAYCCNATGATGCCNATGCARATGGGNATGATGACNCCNATGATG CARCCNATGATG---------CARCCNCARATGCARATG---CARCCNCAYATGAARCAR ACNCCNMGNTTYATHCCNCARGARATHCCNAARACNGAYCCNACNGGNGARMGNCCNCCN GTNACNACNGTNTTYGTNGGNAAYATHAGYGARMGNGCNCCNGAYATGATGATHAARCAR ATGYTNCARMGNTGYGGNAAYGTNYTNAGYTGGAARMGNGTNCARGGNGCNTCNGGNAAR YTNCARGCNTTYGGNTTYTGYGARTAYGARGAYCCNGARGCNACNYTNMGNTGYATHMGN YTNYTNAAYGAYTGGTCNATHGCNCARAARAAYYTNGTNGTNAARGTNGAYGCNAARACN MGNACNYTNYTNGAYGARTAYMGNAARAARAARCARGAYAGYGAYGARAARAGYGAYAAR AARGAYTCNGARACNAARGAYGARGARAARAARGAR------GARAAYGGNGARGAYAAR GAYTCNGTNTCNGAYAARGGNGAYAARGARGARAARGARAAR---GAYYTNGAYGARAAY ACNCARMGNGARGAYMGNGTNGCNCAYGCNGGNYTNGARGCNATHATGMGNGARTAYGCN TTYGARYTNAAYAARGARCCNGTNAARCCNGCNGAY---GCNCARCCNGARAARAARGAR CARCARCCNAARAARGAYAARGARATHTAYATGCAYGCNAARGAYACNGGNTTYGARGAY ATGGARATGGARGAYGARAARMGNGARATHATHAAYMGNGARATHAAYAARTTYMGNGAY MGNCAYAARNNNNNNNNNGANNNNNNNNNNNNNNNN---GARAAYAARGARMGNAGYYTN GCNMGNGARMGNGARMGNMGNCARGARGARAARMGNCARMGNGARMGNYTNGARAARATG MGNATHGARMGNGAR---------------------AAYMGNGARAARGARMGNGCNAGY GCNMGNGTNTCNMGNTCNAARTCNMGNTCNGCNTCNCCNGCNCCNTCNMGNTCNMGNMGN MGNTCNMGNTCN------------MGNGARMGNAAYAGYMGNGAYMGNTCNMGNGARMGN MGNAARGARMGNGARYTNGARGARGARGARGARYTNTAYGARMGNMGNAARYTNGARAAR AARYTNMGNGARAARGARGCNGCNTAYCARGARMGNYTNAARAAYTGGGARGGNMGNGAR MGNAARAARGCNMGNGARTAYGARAARGARAGYGAYMGNGARGAYGARMGNAARGTNGAR GARACNMGNGARGCNMGNMGNYTNAARGARTTYYTNGARGAYTAYGAYGAYYTNMGNGAY GAYCCNAARTTYTAYAARGGNAGYGCNYTNCARMGNMGNCARAARGARMGNGARAARGAR AARGARYTNGAYAAYMGNGAYMGNCARMGNGARAARGARGARTTYGARGARATHAARMGN AARYTNTTYGAYGARGGNCAYCCNGAYGCNGARACNGARGTNGCNMGNATGGARMGNGAR MGNGARGARCAYYTNCARCCNCARYTNCARYTNCCNGARCCNAARCARCCNTCNCCNCCN AAYAARGAYACNGAYTCNGAYACNTCN---------------------------CAYCAR GCNGAYGCNMGNCARCCNTCNCCNAARTCNTCNGARCAYYTNTCNTCNAGYAARAAYGCN ---------------------------------------------GTNATHGARCAYMGN AARTCNCCNTCNYTNTCNACNTCNCCNATHTCNACNGAYTCNMGNGTN---AGYGCNCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------GTNCCNGTNGCNAGYCCNGAYTCNTCNAGYYTNCCNGGNGTNACNAAY GTNACNGAYGGNAARMGNAARAARYTNACNATHGGNGAYGTNTTYAAYCARGAYGAYGAY GAYAGYAAYGARCCNAARAARMGNAARYTNATHCCNYTNGAYTAYGAYGAYGAYAARTCN ACNCCNCCNGARAARAARGGNTCNACNGCNGARGARAARMGNCAYMGNATHAARCARYTN ATHGARAAYATHCCNACNGCNAARGAYGARYTNTTYGCNTAYACNGTNGAYTGGGAYATH GTNGAYCARGCNYTNATGGAYAARMGNATHAARCCNTGGGTNACNAARAARATHGTNGAR TAYATHGGNGARGARGARCCNACNYTNACNGARTTYATHTGYTCNAARGTNGTNGCNAAR AGYACNCCNCARAGYATHCARAAYGAYGTNGCNATGATHYTNGAYGARGARGCNGARGTN TTYGTNGTNAARATGTGGMGNYTNYTNGTNTAYGARACNGARGCNAARAARAAYGGNYTN GTNAARYTNAARATGGARGARTAYCARYTNCAR---GTNCARMGNTGGCCNMGNGAYGGN AARCAYATHATGGCNCAYTAYGAYGAYGAYATGGTNGTNGTNTAYCARGCNTAYAARCCN AGYATHGCNGAYTAYGTNGTNAARCAYCARAARTTYGGNGGNCCNGAYTTYAGYTTYGAY MGNATGTCNTGGATHAARCCNAAYTTYATGTGGATGATGTAYMGNTGYGGNTGGGCNCAR AARAARAAYCARGARMGNGTNYTNGCNGTNTGGYTNACNMGNGCNGGNTTYGAYCAYATH ATHGCNACNGCNAARACNGGNMGNGARAGYGAYMGNCARTCNAAYAARTCNGAY------ GARGTNMGNYTNCARTGGGAYCCNGAYCAYGAYCCNCAYGGNGAR---AARYTNCCNMGN MGNGCNATHCARYTNGGNYTNMGNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNMGNGGNTTYGTNCCNAARMGNMGNCCNATHGCNMGNYTNGGNCARYTN GGNACNACNGGNMGNTTYTGYGTNATHGTNGAYGCNGARAGYTGYYTNGAYMGNYTNTAY GGNGGNTAYTAYTCNGAYTGGGTNTGYGGNGGNCARTGGAAYMGNATGACNGCNTTYYTN ACNAAYYTNGTNCARGCNTGYCAYAAYGGNAAYATGGARYTNGTNGTNTTYTTYAAYGGN GCNYTNGARAAYCARAARATHAAYGARTGGATGTCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATGGCNGAYGAYTCNGAYATHCCNCCNYTNGARGAYATGACNGAYATHYTNCAR AARGCNGARYTNATHMGNGARCAYMGNAARTCNTCNAARGARCARAAYACNAAYCARAGY AARATHATHGARGCNAARAARAARGCNAARGTNACNAARAAR------------------ ---------------------------------GTNACNGAYGCNACNAGYAAYCCNTCN ACNCARAGYGGNAARAGYGTNGCNAAYYTNCARGARAARCCNGARACNGAYATHAARAAY GARTCNGTNAARAAYACNAGYAAYACNAARCARGGNATGTTYGGNGGNATGAARAARGGN TTYYTNTTYGGNGGNGCNAGYAAYAARCCNTCNAARACNGARAGYAARACNCARCARATH TCNCARCARTCN---AARGGNGARAARAARCCNGCNACNAARCCNGTNAAR--------- ---------------------GAYGAYYTNCCNTAYATHTCNCCNTCNGGNAARACNGAR TCNGGNYTNGCNTTYGAYGARGTNCARAARGCNATGTCNGARGCNAARGGNYTNYTNAAY AAYCARGARTGGATHACNGAYGAYTTYYTNAAYAARATHGARAARAAYGARACNYTNYTN AARMGNTTYACNGAYCCNAARTTYATGTCNGCNYTNCARGARTTYCARACNAAYCCNCAR GCNGCNATG--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARCAYAARMGNGTNCAYAARGGNTCNYTNYTN YTNCARGAYAAYGARAAYGARGCNYTNTTYCARACNYTNGGNMGNYTNTGYGTNACNYTN TCNACNGGNGTNGTNCARYTNTAYYTNGCNGAYCARCCNGAYMGNACNMGNTGGAAYAAR MGNTGYTGYGGNGTNGTNTGYTTYGTNAARGAYAGYTCNAARMGNTCNTTYTTYATHMGN ATHTAYGAYATHAARAARCARCARYTNYTNTGGGARCARGARATHTAYAAYCARTTYGTN TAYAARGCNCCNMGNGARTAYTTYCAYACNTTYGARGCNGAYAAYTGYCARGCNGGNYTN AAYTTYGCNTCNGARGAYGARGCNATHAARTTYMGNGARACNYTNGAYGGNAARYTNATH GARMGNMGNMGNAARAARATGGARMGNMGNCARAARGCNGGNGTNAAYAARCARGGN--- ------CARGGNGCNACN---------------CCNCCNCARMGNATG---GGNCAYAAY YTNACNCCNAGYCCNGCNCCNACNACNGTNGARTTYAAYMGNCCNGCNAAYACNAGYACN ---------CARAARAARGAYAARGAYAARAARAARGAYGGNAARAARAARYTNACNAAR GCNGAYATHGGNACNCCNTCNAAYTTYATGCAYATHAGYCAYGTNGGNTGGGAYCCNGAY MGNGGNTTYGAYATGAAYAAYYTNGARCCNGAYATGCARACNYTNTTYCARTCNGTNGGN ATHAARCCNGARGAYGAYGTNGAYAARGARACNYTNGAYTTYATHTAYGAYTTYGTNGAR AARCARGGNGGNATHGGNGCNTTYAAYGARGARYTN---------CARGGNAGYACNAAR AARGCNCCNCCNCCNCCNGCNAGYGTNCCNMGNGGNGGNCARCCNCCNCCNCCNCCNGCN MGNATHCCNGGN---GCNCCNCCNCCNTCNMGNGCNGGNGGNGCNCCNCCNCCNCCNCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYYTNTAYAAYACNGTNCARGCNAAY GARGCNYTNGARGGNAARGTNGTNTGYYTNTTYTTYTCNGCNTCNTGGTGYACNCCNTGY CARCAYTTYGTNCCNAAYYTNAARGARGTNTAYTCNGAYYTNATHCARMGNAAYACNCCN GTNCARGTNGTNTTYATHAGYTTYGAYAARACNGARGARGARATGATHAAYTAYTAYMGN GARAARCAYGGNGAYTGGYTNGCNGTNAARTTYGGNGAYCCNATHAARGARGARYTNGTN GARAARTAYTCNATHAGYGTNATHCCNAARYTNGTNGTNATHCARCCNGAYGGNGARGTN ATHAGYGCNAARGGNMGNAARGAYGTNCARGAYMGNGGNGTNGTNTGYATGMGN------ ------------------------------------------MGNTCNTCNGTNCARYTN TTYACNATHAARMGNGTNGARATHYTNACNYTNYTNCARYTNGCNAAYATGGTNYTNTGG ATHTTYGAYGTNCAYTAYAARTTYATGCCNGTNGCNATHYTNCCNGCNYTNATGATHTTY GTNGGNYTNYTNGGN--------------------------------------------- ------------------------------------------------------------ ------------------------AAYGTNTCNGGNATGMGNAARCCNTAYAARGGNAAR CARGAYATHTTYGAYGTNAARGAYYTNACNTCNAARGARCCNTTYGCNCARTTYAAYGCN TGGTTYGARGARGCNAARACNACNCCNGGNATHATGGARGCNAAYGCNATGGCNYTNGCN ACNGCNACNAARGAYGGNATHCCNTCNGTNMGNATGGTNYTNATGAARGGNYTNAGYAAR GAYGGNATHGAYTTYTAYACNAAYTAYYTNAGYMGNAARTCNCARGARYTNATHAGYAAY CCNCAYTGYAAYYTNATGTTYTAYTGGGARCCNYTNATGAARTCNGTNMGNATHGARGGN AARGTNCARAARYTNAGYCARGARGAYTCNAGYAAYTAYTTYCAYTCNMGNCCNMGNTCN AGYCARATHGGNGCNTGYGTNAGY---GARAGYCARAGYTCNGTNATHCCNTCNMGNGAY GTNYTNGAYAARMGNAARGARGAYYTNGARTCNYTNTAYGGNGAYGARAGYGTNGARATH CCNAARCCNGAYTAYTGGGGNGGNTTYMGNGTNGTNCCNTAYAARTTYGARTTYTGGCAR GGNCARACNAAYMGNATHCAYGAYMGNATHATHTTYMGNAARCCNGCNGARGGNGARGTN ATHGAYCCNACNGTNACNTTYAARGGNGAYGARGGNTGGGTNTAYGARMGNYTNCARCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TTYGGN TCNATGYTNYTNCAYATHCCNGAYTAYATHTTYATHAARATHAARACNGCNTGYGARCAR TCNGGNYTNAAYGTNGTNTGGMGNTCNGAYCARGAYTCNCCNGAYTCNAARMGNTTYYTN AAYTCNAARTGGGTNCCNCARAAYGAYATHYTNGGNCAYGCNAAYACNAARYTNTTYATH TCNCAYTGYGGNAARAAYGGNCARTAYGARTCNYTNTAYCAYGGNGTNCCNATHYTNTGY YTNCCNATHTTYGGNGAYCARCCNTAYAAYGCNGARMGNGTNGTNATHAARGGNTAYGGN YTNAARGCNGAYATGMGNTTYACNACNACNCARCARYTNGCNACNACNATHCARGARYTN GTNACNAAYTCNACNTAYMGNAAYAAYATGGTNAARGCNTCNMGNYTNTTYMGNGTNATG TAYAARTCNCCNATGAARGARGCNGCNTTYTGGYTNGAYCAYGTNATGGARTAYGGNGGN GARTAYATGMGNGCNTCNACNCARMGNATGCCNTAYTAYCARTTYATHATGYTNGAYATH TTYGCNATHATHGCNYTNGGNATHYTNYTNTCNTGYYTNAGYATHGTNTGYGTNYTNCAR AGYATHTCNCCNYTNCARYTNTGYTCNMGNCARTTYMGNAGYMGN--------------- ---AARCCNAARYTNATHCCNAAYCARAGYGGNGGNTCNTTYTCNTTYGGNAARTCNGCN YTNTTYACNGCNGGNGTNTGYAGYTGYAGYTTYYTNGGNGCNATGGTNTGGAAYTAYGAR AAYGTNMGNCARGTNTAYAARGARATG---GCNGCNGARAGYACNTCNCCNMGNCAYCAY MGNTTYATHCAYGARAARGTNTTYGGNTTYMGNAAYCAYYTNAAYGCNATHTGGAAYGGN ATGGAYCARTCNACNAARYTNACNTTYGGNATHATHGCNGTNAAYTCNGCNGTNTGGYTN YTNTGGAARGTNCCNMGNTTYCARYTNAARATGATGMGNTAYTTYTCNTCNGCNGCNGCN CAYCCNMGNGTNTCNATGGTNTTYAGYAGYTTYAGYCAYATHAGYTTYTTYCAYYTNGCN ATHAAYATGTAYGTNYTNYTNTCNTTYGCNCCNATHGCNGCNAARACNTTYGGNCAYGAR CARTTYTCNGCNTTYTAYATHAGYGCNGGNACNATGTCNGCNTTYGCNAGYATHGTNTGY CARAARGTNYTNAARMGNCCNYTNGCNGTNTCNGTNGGNGCNTCNGGNGCNATHATGGGN YTNYTNGGNGTNACNGGNGTNGTNTAYCCNAAYGCNCARYTNCARGTNGCNTTYGTNTCN GARATHTTYCCNCAYTCNTTYTCNGCNGAYTCNGGNGTNAARGCNATHGTNYTNTTYGAY YTNYTNGGNYTNYTNATGGGNTGGAARGTNYTNGAYCAYGCNGGNCAYYTNGGNGGNATG YTNTTYGGNATHYTNTAYGCNAARTAYGGNAGYAARTAYGTNTGGGGNCARMGNGAYTCN GTNGTNAARGTNTGGCAYCARYTNMGNGGNAARCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARCCNTTYCAYYTNAGYGTNGAYGARMGNGGNGAR MGNTAYCARAARGARTTYAARGCNAARCARATGGARGARGARAARGARGAYYTNAARTCN AARTCNMGNTTYCAYGCNTCNTCNAAYAARGTNATHTTYAARGCNCCNTTYGTNCCNGAR AARACNAAYAARCCNYTNACNGARATGAGYTCNTTYACNYTNAAYACNGAYCARMGNGCN GTNATGMGNGARCAYTTYAAYCARCARGCNAARGCNGCNGARGCNGARATHGARGCNYTN AARMGNCARMGNGARGAYMGNAARAARMGNGARGARCARGARGARATHTCNAARYTNMGN CARGARATHGTNCAYAARGCNACNGGNATHAARAARTAYAARAAYGTNAAYCCNCAYCCN AGYGAYAARCCNYTNACNGTNGCNGARTCNCCNTGYYTNMGNACNAARGTNMGNTCNMGN MGNCAYATHGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ACNAGYGGNCCNCAYMGNCCNYTNTGG CCNAARTAYGGNGARTAYYTNTAYYTNCCNCCNCARMGNTGGATHCAYACNYTNGARCAY GGNGGNGTNGTNTTYYTNTAYAAYCCNTGYGCNAAYCCNGAYCARATHMGNAARTTYAAR GCNGTNGCNAARAARTGYYTNMGNMGNCAYGTNATHACNCCNTCNAARMGNATHCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TCNGAYTGYGARAGYGAYYTNAARAGYYTNGAYACNYTNGCNYTNYTN ATHGGNAARCCNCAYGCNYTNGCNGTNYTNTCNTCNATHGARCARGAYMGNACNATGYTN AGYCCNAGYTCNATHAAYAGYATHAAYGGNMGNCCN---------------TCNTCNGAY GGNYTNGAYGGNGAYMGNTCNTGGGARAARCAYACNAAYACNTTYAARCCNCCNGTNCCN GTNGARGTNTAYAAYTCNCARGGNAAYGTNGAYAGYTGYGGNGAYAGYGTNCARAARAAY TCNACNTCNGGNYTNTCNGGNGGNAAYCARCCNGGNAGYATGGARACNYTNAARAAYATG YTNTTYAARYTNCARAARGARGARAGYTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNAARTGGTTYCARCCNATG CARATGAAYYTNGGNGTNCCNACNGARMGNGCNGCNCAYGGNATGTGYGCNGTNGGNMGN AARYTNGTNATHTTYGGNGGNMGNGAYATHGARGAYMGNCARAAYGAYGTNCAYATHTTY AAYATHGAYACNMGNAARTGGGARGCNGAYYTNAGYTTYAGYGGNCARACNCCNGCNCCN MGNTCNTTYCAYACNYTNACNACNGTNGGNAAYAARGTNGTNGTNTTYGGNGGNMGNGGN MGNGCNAAYAAYCAYTTYAAYGAYATHGAYGTNYTNGAYYTNGARAARAARGARTGG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNYTNCCNTCNCAYTGGMGNTCNAAY AARACNYTNCCNGTNCCNTTYAARGTNGTNGCNYTNGGNGAYATHAARGAYGGNACNAAR GTNATHATHAGYGCNGGNAAYGAYGARAAYTTYAGYTCNGARYTNMGNAAYAAYACNGCN ACNATGAARAAYCARGTNGCNAARTTYAAYGAYYTNMGNTTYGTNGGNMGNAGYGGNMGN GGNAARAGYTTYACNYTNACNATHACNGTNTTYACNAAYCCNCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGYTNACNATHACNGAYTTYATHAAYATHYTNAARCARTAYTAYAAYGGN CCNGARACNMGNAAYGARGARYTNGARGARCAYAARATHTCNACNTGGMGNGARGTNYTN MGNGARMGNCARAARCCNTTYGTNTAYATHTCNCCNGAYGCNAGYYTNTTYGAYGCNATH CARAARYTNATHGAYAAYCARGTNCAYMGNYTNCCNGTNATHGAYGARACNACNGGNAAY GCNYTNTAYATHYTNACNCAYAARMGNATHYTNMGNTTYATHCAYYTNTTYTTYAARGAR YTNCCNCAYCCNGCNTAYATGCARAARTCNGTNMGNGARYTNGGNATHGGNACNTAYGAR AAYGTNATHACNGCNACNGTNGAYATGACNYTNATHCARGTNYTNAAYYTNTTYTGYAAY CAYMGNATHTCNGCNYTNCCNGTNGTNGAY---AAYCAYGGNAARATHATHGGNATHTAY GCNAARTTYGAYGTNATHAAYYTNGCNGCNGARAARACNTAYAAYAAYYTNGAYATHACN YTNMGNGARGTNYTNGAYMGNMGNAAYGARGAYAGYGCNGARAAYAAYGARAAYGTNGTN TCNTGYTTYCCNAAYGAYAARYTNGARACNGTNATHGARAARATHGTNAARGCNGARGTN CAYMGNYTNGTNGTNGTNAAYGCNGARGGNGGNGTNGARGGNATHATHTCNYTNTCNGAY YTNYTNAAYTAYACNGTNYTNMGNCCNATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TCNACNYTNGAYYTNGGNAGYGCNYTNAAYGAYYTNGTNGTNCCNGARTAYYTNCCN ATHGGNATHAARYTNYTNMGNAARATGGGNTGGMGNGARGGNCARGGNYTNGGNCCNMGN ATHMGNAARACNAARATHAARACNAARAARAARAARAARAARCCNGARATHAARGTNTAY GGNTGYGCNCCNCCNCCNTCN---TCNTCNGAYTCNGAYTCNGAYCAYTTYYTNGCNTCN AAYATGGCNGAYATHACNTTYGCNCCNAGYGAYATHAGYCCNYTNTCNATHACNGCNAAR ACNGAYGTNAARGGNYTNGGNTAYMGNGGNYTNGAYCCNTCNYTNGCNYTNCCNTCNTCN CAYGTNAAYYTNTTYAGYGARCCNGTNMGNGTNAARGGNMGNGGNAARGCNATHMGNGGN CARGCNTTYGGNGTNGGNGCNYTNGARGAYGAYGAYGAYGAYATHTAYGGNACNGAYAAY YTNTCNAAYTAYAAYYTNACNYTNMGNGAYGAYGAYGAYGAYGGNGGNGGNCAYTTYGGN TGGACNGCNCCNMGNTCNCAYGGNAARCARCARGTNCCNGTNTCNTAYGTNGGNAAYYTN YTNGARGGNTTYATHYTNTCNTCNAARCCNYTNAARCCNGCNAARMGNTAYCCNGCNCCN ACNYTNCCNGCNGAYTTYAARCCNTTYCAYTGGACNMGNMGNMGNAARAARCAR------ ------------------GAYTCNAARGGNATGAGYGCNGTNGAYMGNGGNYTNYTNYTN GGNGARAARCCNATHATGAAYTCNGTNTTYGAYYTNGTNACNGCNTCNGAYAARAAYMGN GTNGCNGCNACNCARGARGCNATHAARATGAAYCARTCNYTNAARGAYTCN--------- ---------------------------------TCNCAYTCNTCNCAYATHCCNGARGAR GCNGAYMGNAARCARGARGTNGARMGNGARAARATHGTNGGNCCNTCNTTYGTNTCNAAR TTYACNCCNGCNGTNGAYAGYCCNGCNGAY---------------ACNCCNCCNGCNCAR CCNCARTCN------TTYACNACNTCNTTYGCNYTNMGNCCNTTYCAYAARAAYACNACN AARCARGCNMGNTTYGAYCARTAYYTNAAYAAYGTNAARCARMGNGTNCCNGAYCCNTAY GCNTCNYTNTCNTCNMGNGAYATGACNGARTGGGARMGNGCNMGNGARAARGARGARTTY GGNMGNTCNGCNAARYTNTAYMGNCCNATGTCNGCNATGATGGCNTCNMGNTTYGTNCAR GGNGCNATGYTNGAYGAYAARGTNGARGAYACNGAYAGYAARGTNAARGAYGTNCCNACN GAYGARGGNAARGCNGTNGARATGMGNATGTTYGGNAARYTNACNMGNCARGARGARGAR TGGCAYCCNGAYAARYTNGTNTGYAARCARTTYAAYGTNCCNAAYCCNTAYCCNGGNTCN GAYATHGTNGGNYTNCCNAAYGTNAARMGNGAYAARTTYTCNGTNTTYAAYTTYYTNAGY ATHGGNGAYTTYMGNCCNAARGAYACNACNYTNCCNGAYTCNCARGARACNAARGARAAR CCNAARAAYGAYAARGARYTNAARCCNGAY---------------------AARAARAAR GCNACNYTNTCNTCNATHTTYAARGTNYTNGAYGAYCCNGAYTTYCAYCARGCNCCNGAY AAYCARCCNACNACNAAR---------------CARGAYGARAARCARYTNATGGCNAAR GARGAYGARGCNGARGCNGARGARGARGARGGNGAYGARCCNGAYGTNGAYYTNTTYMGN GCNATHTTYAARAAYTCNGAYTCNGARGAYTCNGARGAY------AAYTCNGGNAARAAR TCNGAYCARTCNGTNAGYGARGGNMGNGARGARAARGAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TCNATHACNGTNTGYYTNCCNAGYAAYTCNGCNCARGTNGTN MGNAARGARYTNGARCARYTNGARATHTGGGAYAGYAGYMGNAARYTNTCNAARCARGGN AGYMGNGTNGCNATHCCNATHYTNACNTGYACNTCNAARTCN------------------ ---------------------------------CARYTNGAYAGYTTYTCNCCNATHATH CCNTCNATHAARGCNACNAGYYTNYTNACNGARATHCCNAARAARTGGGARMGNCAYGGN GAYYTNATHATHYTNCCNTCNACNGCNTTYMGNTCNYTNGARTGGCARCARATHGGNGAY GARYTNTGGAARTGYGTNTGYATHGCNYTNGTNTGYCARMGNATHGCNCARCAYAGYCAY GTNGCNAAYGAYGGNTAYMGNTCNCCNCARGTNTTYATGYTNTAYGGNGAYAAYGGNGAY GTNGTNCAYGTNGAYAAYGGNATHAARTAYAGYTTYGAYGTNACNAARTGYATGTTYAGY TCNGGNAAYATHAGYGARAARYTNMGNGTNGCNAGYTGGGAYTGYTCNAAYCARGTNGTN GTNGAYYTNTAYGCNGGNATHGGNTAYTTYACNYTNCCNTAYYTNGTNCAYGCNAAYGCN AGYCAYGTNCAYGCNTGYGARTGGAAYCCNGAYGCNGTNGCNGCNYTNAARAAYAAYYTN GTNYTNAAYGGNGTNGARCAYMGNTGYACNGTNCAYCARGGNGAYAAYMGNAARYTNCAR YTNTGYAAYGTNGCNGAYMGNGTNAAYYTNGGNYTNATHCCNACNAGYGARGAYGGNTGG TGYGTNGCNACNMGNGTNYTNAARTCNTCNGGNGGNGTNYTNCAYGTNCAYCAYAAYGTN ACNGTNCARTCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNACNYTNATGAARGARGARAAYACNYTNMGN ACNAARGTNGARGCNYTNAARACNGARAARAARGAYMGNATGACNAARTAYGARGARYTN CAYTCNAARGARGARAARYTNTGYGARCAYATGGCNGARATHCCNTAYTAYATHGCNTCN GGNACNGTNCCNAGYYTNCARCARYTNAARGARYTNGARGCNCAYGTNAARAARYTNCAR ATHGARGARGGNAARMGNACNTCNGAYTAYAAYGCNATGAARAAYGARATHTGYACNYTN TAYAAYGARATGGARYTNGAYCCNGARACNTCNATHGCNCAYGAYGTNTAYTGYGARGAY GCNGAYAAYTTYACNYTNTCNAARACNAARATGGARGARYTNAARAARYTNCARGARGAR YTNGTNCARAARAAYGAYCARATGAARYTNGARGTNGGNGAYYTNTGGGAYMGNYTNAAR GCNYTNTGGAAYMGNYTNGARACNCCNGARATHGARMGNGARGCNTTYTCNYTNGAYAAR ACNGGNCAYGGNCAYAARYTNATHACNGGNYTNAARGCNGARATHGCNGCNTGYGARGAR YTNAARYTNCARAAYATHAAYAARTTYATHGARGGNATHMGNACNGARYTNGTNTCNTGG TGGGAYAARTGYTTYTTYAGYTCNGAYCARMGNAAYAGYTTYGARTTYTAYGARGARGCN AAYTTYACNGARGAYYTNYTNGARGCNCAYGARAARGARYTNGARAARYTNMGNGARTAY TAYAGYCARMGNMGNGAYATHYTNGARAARATHGCNCARMGNGARGTNYTNTTYAARAAR ATGGTNGARTTYGAYMGNAARGCNAGYGAYCCNAAYMGNTTYTTYAAYGAYMGNGGNGGN AARYTNYTNCARGARGARAARATHMGNAARAARGTNYTNAARGAYYTNCCNAARTTYGAR GARGARGTNGCNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNACNACNYTNATGTCNTCNTTY MGNGAYMGNGTNMGNGARTCNTCNATHGCNGCNAGYAAYTTYAARGAYTGYGARMGNGAY ATHTTYGARCAYTAYCAYACNTAY------------TCNACNAARYTNGAYCAYTCNTTY TTYGAYGTNCCNTGYACNGARYTNGCNCARMGNYTNYTNGGNCARTAYATHGTNMGNGCN GTNGGNACNCARMGNATHMGNGGNAARATHGTNGARACNGARGCNTAYATHGGNCCNATH GAYAARGCNGCNCAYAGYTAYCARGGNAARMGNACNGCNMGNAAYGARGCNATGTTYYTN CCNGCNGGNACNAGYTAYGTNTAYAAYATHTAYGGNATGTAYTGYTGYYTNAAYATHTCN AGYCARGGNGAYGGNGCNGCNGTNYTNGTNMGNGCNYTNGARCCNYTNGARGGNCAYGAR YTNATG---------AARGARGGNMGNACNAARAARGAYAARMGNTGYAARCCNYTNAAR GAYAARGAYYTNTGYAAYGGNCCNTCNAARYTNTGYCARGCNYTNCAYATHACNAARGAY GAYTTYGAYCARAARGAYYTNACNGCNTCNAAYTTYYTNTGGYTNGAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGTCNACNTCN TCNGARCAYACNGAYYTNTCNCCNCARAGYTCNTCNTCNCCNTCNCCNMGNAGYGGNAGY GAYGGNMGNCARYTNCCNAGYATHCCNACNGARAGYCCNATGMGNAARCCNGTNMGNAAY GAYAARGGNAAYAAYCCNACNAGYGTNGAYYTNMGNGGNAAYAAYGGNTAYGGNCCNTTY TTYYTNGARTAYTCNYTNATGGCNGARTTYAAYCARGTNCAYCAYCAYCAYATHCCNGGN YTNTAYGCNATGCCNTCNTCNAARTCNCCNYTNATHTGGTCNGGNYTNATHTTYATHMGN CARGGNTTYTAYCARGGNGCNGCNYTNMGNTTYATHYTNAAYATHCCNCAYAAYTAYCCN GAYGGNCCNTGYCCNTCNYTNGTNTTYGARCAYCCNGTNTTYCAYCCNYTNGTNGAYCCN GARACNGGNGARYTNGAYGTNMGNMGNGCNTTYCCNMGNTGGMGNMGNAAYGTNAAYMGN YTNTGGCARGTNYTNYTNTAYGCNAARAARGTNTTYTAYAAYATHGARACNTCNGTNCCN TCNAAYCCNGARGCNGCNGTNYTNTAYGARCARGARCCNGARYTNTTYAARAGYTGYGTN TTYGARTCNGTNAAYGGNGCNAARGARMGNYTNTAYCARCCNCCNTCNTTYGAYGAYCCN TTYGCNYTNMGNTTYACNCCNTGGAAYGARGCNGTNCAYCCNGARGCNMGNMGNCARATG GCNGAY---MGNCARAARAAR------GARAAYTCNTCNGCNAAYCCNTCNGAYYTNGGN YTNTCNTGGGTNGAYCCNYTNGTNCCNMGNATHTTYGCNACNGAY--------------- ------------CCNYTNTTYYTNTAYYTNGCNTAYCARTCNGTNCAY---------GCN CCNYTNCARGTNCCNAAYAAR--------------------------------------- ---------------------GARCARTAYTCNAARCAYMGNMGNACNTAYGCN------ ------------------------------------GGNATGGTNTCNGTNYTNGAYGAR GGNGTNAAYAAYGTNACNAARGCNYTNAARGAYACNGGNYTNTGGGARAAYACNGTNTTY GTNTTYTCNACNGAYAAYGGNGGNCARGTNCAYGARGGNGGNAAYAAYTTYCCNYTNMGN GGNTGGAARGGNTCNYTNTGGGARGGNGGNTTYCAYGGNGTNGGNTTYGTNGCNGGNCCN YTNYTNAARTCNCCNGGNTCNGTNAGYMGNGARYTNATHCAYGTNACNGAYTGGTAYCCN ACNYTNGTNAARYTNGCNGGNGGNGGNYTNAAYGGNACNAARCCNYTNGAYGGNGTNGAY CARTGGAAYACNATHAGYAAYGGNGCNCARAGYAARMGNAARGTNYTNYTNCAYAAYATH GAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNGGNGGN ACNYTNACNTCNMGNAGYTAYTAYCARGARCARMGNATHGAYYTNYTNGTNAARAAYGAY AAYYTNCAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARGAYCARATHYTNAARGTNAARGARYTNATHGARAAYGTNATGGARAAYGGNAARGCN YTNTGYGAYGAYTTYTGYTCNYTNCARGTNCCNYTNACNGTNACNTTYAGYCARGGNMGN TCNTGGGCNCAYYTNAGYCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGGTNGARGCNGAYGTNTCN CCNGGNGAYATHGAYCCNGAYATGYTNGCNGCNYTNGARACNGTNATGGAYGARYTNATH GAYGARGTNACNYTNGGNYTNTGYTTYGARATHCAYMGNTCNTGYAARATHGGNTTYTTY YTNYTNGAYACNGGNGARGAYGTNTCNGAYACNGARTAYGCNGTNATHGARMGNCCNGGN GTNGAYGTNYTNGGNCARATHCCNTCNAARAARAAYTTYGARTGYGTNTGYCCNAAYTGY CARMGNCAYYTNGCNGCNTCNMGNTTYGCNCCNCAYYTNGARAARTGYATGGGNATGGGN MGNAAYTCNTCNMGNATHGCNAGYMGNMGNATHGCNAAYAAYCARAARCAYGGNAGYGAY GAYAGYGGNCARGAYGAYGARAAYGAYAAYGAYTGGAAYTAYGCNCCNGARTCNAARMGN YTNMGNAARYTNAARAARGAYAARATGTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGYGARAAYTTYGTNGAR GARYTNGARAARTTYGARMGNAGYTCNTGYCCNAARGGNMGNCCNAAYACNATGTCNAAY CAYGGNGTNTCNYTNGAYGARATGGGNYTNTCNCCNGGNYTNYTNTCNCCNYTNATHGTN AAYTAYATHCARCCNYTNACNAAYGCNYTNTTYAAYGARMGNTGYAGYGARMGNYTNGAY TCNTTYMGNTCNTTYTCNGTNYTNTAYGGNGCNAAYAARGAYACNGARYTNAAYTTYCAY TAYGAYAAYGCNGARATGACNYTNAAYGTNTGYYTNACNTCNCARTTYGARGGNGGNGAR YTNGARTTYGGNCARYTNTGGGGNGAR------------CCNGCNYTNGARYTNGARACN CARACNYTNAARCAYAARATGGGNGCNGGNATHYTNCAYYTNGGNCARCAYATGCAYCAR GCNTTYCCNATHAARTCNGGNACNMGNTGYAAYYTNATHATGTGGATGMGNAGYTCNGCN ATHMGNAAYAARYTNTGYAARATGTGYGGNTCNATHCCNGAYYTNYTNGAR--------- ------------------------GGNAGYAGYTCNTAYACNAGYAAYACNTGGMGNCAR GCNGCNATGGCNGGNGCNATHTAYGGNGGNGTNYTNTAYGCNACNMGNAAYCCNTAYMGN MGNCARYTNCCNCCNATHTGYACNAAYCARCAYGARATHTCNCCNYTNGGNMGNCCNTAY GGNCAYTTYATHTGYCCNMGNACNAAYGARACNTCNTAYGAYATHTAYTGYTGYGGNCCN AARTAYAARGARTAYTGYTGYAAYGTNACNGARGCNAARATGTAYTAYTAYAARCAYCAY GGNGGNGAYGGNTCNGTNTCNGCNGGNGCNGTNGTNGGNATHYTNATHGCNGTNGGNGTN GTNATHGGNATHGTNGTNTGYTGYTGYAARAARMGNCARAAYGGNGGNGTNATHYTNMGN ACNACNTCNAARGGNGTNTGYAARGAYGCNCARCCNGARGCNCCNCCNGCNTAYACNCCN TCNTAYCCNATGCCNAAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AAYTTYTCNATHAARACNACNTGGGAY GGNCARTAYTTYAGYCAYGAYCCNATHAAYATHTAYYTNAGYCARGCNCCNTGYGGNAAY ATHAARYTNAAYGTNGAYGCNCCNTAYTTYAAYAGYCCNGCNAARCCNGAYGGNCCNGCN GGNCARCCNTTYCCNAARYTNTGGGAYTAYGARGTNGTNGARGCNTTYTTYYTNAAYGAY GAYGAYCARTAYYTNGARATHGARYTNAGYCCNCAYGGNCARCAYYTNYTNYTNYTNYTN AAYGGNMGNMGNAARATGGTNAARGAYCARYTNGCNYTNAGYTTYCARGCNTCNATHGAY GGNAAYCAYTGGACNGGNGARGCNATHATHCCNAARGAYTAYYTNCCNCCNGCNGTNACN AARTTYAAYGCNTAYGCNATHCAYGGNGAYGGNGAYCAYMGNMGNTAYGARTCNYTNTAY CCNGTNAARGARYTNAAR---------GAYGGNATGCARCCNGAYTTYCAYMGNYTNGAR ATGTTYGARCCNYTNGARATGAGYACNGTNYTNAAYYTNTAYAAYCCNAGYTAYTGYTCN CCNYTNTGGAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ACNCARGARGCNGTNTTYTCNATHGTNGGNAARAARATHATHGARAGYTGY GTNGCNGGNTAYAAYGGNACNATHTTYGCNTAYGGNCARACNGGNTCNGGNAARACNTTY ACNATGYTNGGNCCNTCNGARAAYGCNGAYAGYTTYCARCAYGARYTNMGNGGNGTNATH CCNMGNAGYTTYGARTAYYTNTTYAGYYTNATHGCNCAYCARCARGARYTNCAYGGNAAY AARMGNCARTTYYTNTGYMGNTGYTCNTTYYTNGARATHTAYCARGARCARATHTTYGAY YTNYTNGAYCCNACNTCNCARGGNYTNCAYYTNMGNGARAAYATHAAYAARGGNGTNTTY GTNGAYGGNYTNATHGARCARGTNACNTGYAGYCCNAGYGAYGCNTAYCARGTNYTNATH ATGGGNTGGYTNAAYMGNMGNGTNGCNGCNACNTCNATGAAYMGNGARAGYTCNMGNTCN CAYGCNGTNTTYACNGTNACNATHGARTCNAARGARGARGTNGAYGGNGTNCARAAYATH MGNACNTCNCARYTNAAYYTNGTNGAYYTNGCNGGNTCNGARMGNCARAARGAYACNAAY ACNGTNGGNACNMGNYTNAARGARGCNGGNAGYATHAAYAARTCNYTNTCNATGAGYAGY GAYTCNGTNTGGYTNAARAAYTTYYTNGARGCNATGCAYTTYMGNGARGTNTCNGARAAY GARAARMGNGCNYTNCARGAYGTNGTNAAYCAYYTNCAYGARYTNTGYAAYAARAARGAY TCNTAYATHCARTCNGCNAARATGATHATHAARTTYMGNGARGARACNATHTCNACNYTN AARAARCARCAYCCNGGNCAYGARGARGCNGARMGNGAYGAYYTNGTNAARTCNYTNMGN TCNGARATHMGNGTNATHCARCARCARYTNGARTCNAAYCCNCARATGGCNAARYTNTCN GGNGARAAYMGNCAYYTNMGNAGYGARYTNAARCARYTNAARGCNCAYAGYTCNGTNGAR GGNATGYTNAGYGAYACNCARCAYATHGCNMGNYTNGARAARATHTTYMGNGARYTNCCN CAYTTYYTNGGNTCNATGACNYTNAARGCNYTNYTNGARGAYCCNAAYYTNAARAAYCCN CCNGTNATHGARTCNAGYGTNGGNACNAAYAARATHAARAARGARAAY---GGNAGYGAY GGNCCNCARTAYAAYTAYGGNTCNGCNTTYYTNGGNCCNAAYYTNTGGGAYAARTCNTAY GGNATGGAYATHAAYYTNGARTAYATGGAYYTNGARGARTTYYTNTCNGARAAYGTNATH ------------------GGNGARTCNGAYAAYTCNYTNAARGGNATHGTNYTNGAYACN CCNGTNGAYGAYYTNYTNAGYGGNGGNGCNCCNCCNGAYMGNGTNGTNAGYTCNCCNMGN CARTAYYTNMGNACNCCNCCNYTNAGYCCNTCNCARTTYATHACN------GGNAGYTCN TCNAGYAARGCNACNCCNAGY---------------CARCCNGCNACNGCNGCNCCNATH CCNCCNYTNTCNCCNTCNTTYTCNGTNGAYTTYCAYGTNTCNGAYCARGAYYTNGCNYTN ACNACNGTNCCNGAYTAYGARGCNTCNMGNYTNTAYGCNAARGAYCARGARTGGATHAAR AGYGTNAGY---------------------------------TTYGAYCCNMGNAARCAY AAYTTYACNGAYGARGAYYTNAARCCNCARCCNATHATHAARAARTCNMGNAARGTNTTY GTNCCNGARGAYYTNAARGAYGAYAARTAYTGGGCNMGNMGNCAYAARAAYAAYTTYGCN GCNAARMGNTCNMGNGAYGCNMGNMGNGTNAARGARAAYCARATHGCNYTNMGNGCNGCN TAYYTNGARAARGARAAYAARTGYYTNAARGARGARATGGCNAARYTNCARAARGARAAY ACNAARYTNATHCARATHGCNGARAARTAYGARCCN------------------------ AAYMGNCARGCNTTYATGGAYGCNGTNYTNCARGAYCAYCAYCARACNATGGGNATHATH CCNYTNTCNMGNCARAAYAGYGCNGGNAAYGTNYTNGARCARGTNGAYTCNMGNTTYATH AARCAYAAYATGGCNYTNCARMGNATGGGNGGNCARCAYTCN------ACNMGNGTNAAR TCNGCNAARTTYMGNCCNCCNACNGCNAARMGNCARGARGTNAARGCNATGGAYATHTCN YTNMGNGARYTNGTNGGNGAYATHCCNTCNAGYAGYCAYTTYGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AARTAYYTNCARTCNTGYYTNTCNCARAARGCNAAY GGNCARMGNAAYTGGYTNGARAARTGGTGGGARGAYGCNGCNTAYYTNGAYTTYMGNATG CCNYTNCCNYTNATHAGYATGGGNGGNCCNGGNCCNTAYACNGARGAYGTNTGGCCNGCN GARGARGGNACNCARYTNTGYMGNGGNTCNYTNAGYGCNTAYTAYTTYYTNAARTTYTGG CARTTYATHTGYMGNGARCARTAYCARCCNATGAARAAYGGNAARGGNMGNCCNATGTGY ATGTAYCARTTYMGNMGNATHTTYAAYGGNTGYMGNATHCCNGGNGTNTAYMGNGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GAYGGNTGY GTNATHMGNTGYACNATHGCNGARAGYYTNTCNTCNGTNGAYAGYCCNCARCARTCNACN AAYTTYACNGTNTTYTTYMGNAAYCCNAAYGTNCCNGGNATHGGNTCNGGNACNGARCCN TCNTCNGCNGAYAGYTCNGAYYTNGCNATHGGNYTNACNGTNTCNYTNYTNYTNGTNGTN ATHATHGTNGCNGTNGTNYTNTTYTAYGTNTGYTAYTGGMGNAARMGN---ACNCCNGCN GAYAARTAYAARGAYGAYGTNGAYTCNCCNAAYAAY---------------CAYGCNCCN CCNCCNGTNCAYTAYTCNAARCCNAAYAAR---------------------------GCN GCNGGNGGNATHTAYATHCCNAGYCAYTCNCCNTTYGCNCARYTNCCNACNTCNTCNCCN CARCCNGTNTTYCCNAAYGGNYTNCCNGCNGCNMGNTAYGTNGCNGCNCCNCARCCNTAY GCNGTNGTNTCNTCNCCNGGNGGNCAYCCNCAYCCNYTNGCNGCNGCNAAYTAYGCNGCN TCNATGCCNTTYCCNGGNGTNGCNGCNATHCCNACNTCNAGYCCNGCNTTYATHCCNGGN GCNCARTAYCCNGCNAGYATHGGNTTYCARGGNGCNACNYTNAGYAGYMGNTCNATGCCN CCNACNCARTAYGCNATHCCNGCNCCNATGCARGCNGGNGCNCCNYTNTTYGCNGCNGGN TAYTCNCCNGTNCAYGCNGGNATGCCNGCNCCNGCNGGNGCNMGNCAYYTNCCNATHGGN CCNYTNGCNGCNYTNCCNCCNGGNTAYGCNTAYCCNTCNGCN------------------ ---------AARGAYGTNYTNATHYTNACNTGYGGNGGNACNATHGAYAARCARTAYCCN CARGGNCCNGGNGCNTAYGCNTTYGARTTYGGNGAYGARGCNGTNAAYAARATHYTNCAY MGNATHGGNACNACNATHCCNTAYACNTCNGARAARATHTGYGCNAARGAYAGYCARGAY ATGACNGAYTAYGAYMGNGARGTNATHYTNAARGCNGTNAGYGARMGNAARCARTCNYTN ATHYTNATHACNCAYGGNACNGAYACNYTNTGYGAYACNGCNCAYTAYYTNGTNCARGCN GGNATHGGNCARGGNAARTAYTTYGCN---GGNGTNGGNGGNAARACNGTNGTNYTNACN GGNGCNTTYAARCCNGARGCNATGAARGAYTCNGAYGCNGAYTTYAAYATHGGNTTYGCN ATGGGNATHYTNCAR---AGYTCNTGYCCNGGNGTNYTNGTNGCNATGGARGGNATGGTN TTYGAYGGNGCNAARGTNGARMGNAAYGARMGNGGNAARTTYGTNGARGCNMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY TAYGGNYTNTAYGARAGYATHACNGARAAYTCNTAYAGYAAYGCNACNTCNATHTCNCAR ACNYTNAARGAYGTNYTNGGNGAYGTNAARAARGCNTTYGAYAAYGAYGTNACNCCNTTY TTYGCNYTNTTYATHTGYTGYTGGGGNACNGTNTTYYTNGARGCNTGGAARMGNCARTGY GCNACNYTNGCNTAYGARTGG--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GGNYTNGCNYTNAARTAYGGNGTNACN GTNCARGAYATHAARTGGGARATGGTNCARCARCCNTTYAARAARGAYTCNMGNGTNTGG YTNCAYAARAAYTCNAARMGNAARCAYCCNGGNACNGARYTNACNMGNGTNTAYMGNAAY AGYTCNTAYMGNCARGAYGCNGGNTTYGCNTTYGARGARGARGGNTGGGAYAAYAGYCCN TAYATHACNGGNGCNGAYGGNAARGTNTAYAARAARGAYAGYMGNACNTGGYTNCAYAAR AGYTCNAAYAARATGYTNTCNMGNTCNGGNMGNGCNGARACNMGNAGYMGNGCNAARGAR GAYATHAARMGNGTNATHAAYGCNATHGAYAARGTNMGNAARTGGGARAARAARTGGGTN ACNYTNGGNGAYACNTCNGTNACNATHYTNAARTGGGTNCCNGTNACNGCNCARGARAAY CCNGGNGCNYTNMGNAARATHCCNGGNGTNAARACNAARACNTAYTCNAARGCNMGNGTN GARMGNGARMGNGARYTNTAYGCNGCNGARACNAAYGGN---GGNMGNGCNAAYTCNCCN GCNGAYTCNCCN------CCNACNAAYYTNTCNAAYACNAGYTCNCCNTCNTCNAARACN GTNAAYTCN---GARAARACNMGNAAYGGNGGNGTNGTNAARAAYACNAAYGGNTCNGTN GTNTAYACNGARGARAGYACNCARCARTCNGTNGGNTCNTTYTGYTCNGARAAYATGAAY GARGAYTCNAAYATGTCNTTYCCNGARAAYAGYGARYTNAGYGARCARGCNGARAAY--- GARTTYTCNCAYGAYAGYAAYGAYGGNGAYCCNGGNATGMGNGTNGCNATGAGYATGGTN MGNGAYGARGAR------------------------------------------------ ------------------------------------------------------------ ATGTCNGARAARCAYAGYTTYGGNGTNGCNCCNGTNACNTGYCAYGCNTTYAGYAARGAY MGNAAYGGNYTNGCNATGTCNYTNAAYGAYTCNGAYGTNAARGTNTTYAARAARTCNGCN AAYMGNTGGGARGARACNGAYACNYTNAGYGARCAYGGNCARMGNGTNACNAGYATHGAY TGGGCNCCNAAYAGYAAYMGNATHGTNACNTGYTCNGCNGAYMGNAAYGCNTTYGTNTGG ATGYTNGARGGNGGNAARTGGAARCARGTNYTNGTNATHCCNMGNATHAAYMGNGCNGCN ACNTGYGTNAARTGGTCNCCNYTNGARAAYAARTTYGCNGTNGGNAGYGGNTCNMGNYTN ATHGCNATHTGYTAYTAYGAYGTNGARAAYAAYTGGTGGGTNAGYMGNCAYATHAARAAR CCNATHMGNTCNACNGTNACNTGYYTNGAYTGGCAYCCNAAYAAYGTNYTNYTNGCNGCN GGNTCNACNGAYTTYAARTGYMGNGTNTTYTCNGCNTAYCARAARGARGTNGAYGARMGN CCNGGNGCNTGYTCNTGGGGNACNAARATGCCNTTYGGNGCNYTNATGGCNGARTTYAGY AAYGGNGGNGGNGGNTGGGTNCAYTCNGTNAGYTTYTCNCCNAGYGGNGCNGTNGTNGCN TGGGTNGGNCAYGAYTCNAGYGTNTCNATHGTNGAYTCNACNCARGGNAAYCAYYTNATH GTNATHAARGARAGYTTYYTNCCNTTYATGAGYATHAGYTGGGTNACNGARAAYTCNYTN GTNGCNGCNGGNTAYGAYTGYAAYCCNATGGTNTTYTCNTAYAAYGGNGGNAARATHAGY TCNCARGGNAARYTNGAYGTNCCNCARCAYAARGARTCNGGNACNATGAGYGCNATGAAY MGNTTYAARAAYYTNGAYMGNAARGCNACNGAYAGYGAYAGYTCNCCNGARATGAARACN CARCAYCARAAYACNATHACNCARGTNTCNATHCAYACNGGNGAYAARTCNAAYGCNACN AARGTNGCNACNAGYGGNGTNGAYGGNAAYYTNATHATHTGGGAYYTNAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNAAY TAYTTYYTNATHCCNATHTTYYTNGAYAARGTNTGGGARTTYYTNAAYTAYACNCARTAY ATHYTNYTNGGNGTNYTNGTNGGNYTNTAYGTNYTNAGYYTNATHTAYGTNAAYCAYGTN MGNTCNACNYTNGGNYTNCCNAARATGATHGTNTTYGAYYTNGAYTAYACNYTNTGGCCN TTYTGGGTNGAYACNCAYGTNGAYCCNCCNTTYAARATHGGNAARGAYGARAARATHTAY GAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GAYGTNMGNAARAARYTNAAYATGTCNGARACNAGYTCNCARGAYTCNAGYYTNTAYYTN GAYMGNTCNGTNACNAARGGNTTYTCNGCNYTNGARGAYGCNMGNMGNYTNYTNTCNTCN CARATGACNAARGCNTCNGARMGNACNTTYAAYCAYAGYATHGARCAYAARGAYAARTAY MGNCCNTAYMGNCCNCCNGGNTGYAARGARGTNTAYTAYACNGARAGYGAYACNGCNTCN GTNGCNGAYAGYGTNACNACNATGGARAGYACNCAYATHGGNTCNGAYGAYGCNMGNGGN CCNAGYTTYCCNTCNCAYGTNYTNGGNTCNMGNAARGAYCCNCCNAGYACNACNGGNATH TAYGGNACNAARAAYYTNTCNACNGTNMGNGARGAYGTNGTNYTNGGNACNATHGARGAR AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNGAYTCNTGGTCNGTNATHYTNAAYGGNGARGTNGARGTNGTNMGNCCNGGN GGNYTNMGNGARMGNYTNCARATGGGNGAYAGYTTYGGNATHAGYCCNACNATGGARAAR YTNCAYCAYCARGGNGTNATGMGNACNATHGTNAAYGAYTGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARAGYCAYCARMGNMGNTGGAGYMGNCAYYTNAARTCNATGYTN MGNCARCARACNACNCARYTNAARGAYGTNAARAARYTNGTNAAYCARTAYMGNATHYTN GARAARGARAGYATGGARYTNAARAARGARAAYAGYTAYYTNAARTGYYTNYTNGCNAAR AAYGAYCCNGGNYTNMGNGCNGCNTCNCARTTYAAYCCNCARATGTCNAAYAAYCCNCAR TCNTCNAGYATHATGMGNATHYTNATGMGNACNCCNCCNTCNGARMGNATGATHGTNTAY AARTGYGTNATHACNGAYGAYGARATGTTYACNGAYAGYGTNCCNTTYGARGAYAARGGN GGNTTYTAYGTNYTNAARGGNAARTAYGTNACN---MGNAARGCNGAYGARGTNGAYGAY AGYGCNATHGGNGGNAAYCCNAGYGCNGARGARGCNGAYGAR---GGNACNGAYGCNGGN TCNGARTCNGGNATHAAYGTNGTNATGGAYAGYMGNYTNAARGARACNGGNTTYGGNTCN AARAARGARTAYCARGTNTAYATGAARGAYTAYACNAARAGYATHTTYGCNGARYTNGCN AARACNAARTCNGCNGARGARGTNGCNAARYTNAARGARGARTAYACNGARGCNTTYAAR GARGCNTGYGGNAARTTYAARGARTGGCARTTYTTYACNGGNGCNAGYATGYTNCCNGAR GGNCAYACNGCNYTNGTNGARTGG------GTNGAYACNGARGGNGCNACNACNTCNGTN CCNTAYYTNTAYTTYTAYAARGCNGGNATHTCNGCNGTNAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNYTNAGYTGYYTNGTNYTN YTNGGNGTNCARGTNACNGARGCNTCNTCNGAYAAYACNGCNATHYTNTGYAGYTCNGTN TGYTGGGCNGARAGYGCNYTNGCNGARCARTGYGARGTNTCNAAYAAYTGYGAYCCNCAR ------AARCARTCNGAYGAYGARTAYAAYMGNTGYAGYGAYAGYTGYTAYAGYCARGCN GCNMGNTGYMGNAARYTNTGYAARMGNCAYTTYTAYGCNGTNTAYGGNCARTGYMGNCAR MGNTGYACNGAYCAYMGNTTYGARCAYTGYATHACNAAYTGYTTYACNGAYAARATGYTN ACNGTNAAR--------------------------------------------------- ------------------------------------------------------------ ---------------------CARGGNCCNCCNAGYAAY---GGNAAYCARMGNACNGAR ATHAARGARCARATGTAYCARGAYAARYTNGCNCARATHAARAARCAYATHCARATGYTN GARGARGGNACNYTNCARGARTTYYTNAARMGNACNAARAARATHGARYTNAAYTAYMGN GARMGNYTNMGNGAYAAYGARATHTGYAARAARGTNGAYATHGARAARGCNGARCARAAY TAYYTNATHGAYTGYGARAAYGCNCARAARGARTTYGARGARAARGGNGARGCNYTNAAR GAYACNYTNATHTGYMGNYTNAARGARAARAARATHGAYYTNAARGARACNYTNATHAAY GAYCARAARGARAARMGNAGYATGATHGARYTNGARMGNCARACNATHGAYATHAAYGGN GTNGAYTTYATGGARGTNAARCCNACNATGACNMGNAARYTNMGNMGNMGNCCNAAYGAY CCNATHCCNATHCCNGARAARMGNMGNAARCCNTCNCCNGCNCARGTNAAYATHYTNYTN GAYGAYGAYYTNATHYTNGCNGAYYTNMGNGTNATHATGAARGTNAGYGGNAARCCNGTN GCNAARMGNCAYGGNYTNAGYAGYCARAGYCCNCAYATHGAYTCNAAYTCNGAYGTNMGN ATHGARGAYGGNMGNYTNTGGTAYGAYAARAARTGGTTYCARMGNAAYAGYATGGTNCAR ATHGAYAAYAARGARAAYGGNTCNMGNATHTGYGGNACNATHGCNAAYATHYTNAAYAAY GARATHTGGGTNAARAARAGYGGNGAYAAYTCNAARYTNMGNATHTGYGTNTCNCAYATH CARAARGGNAARTAYACNATGAARAARMGNACNACN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTCNMGNGCNGCNCCNGGNAARACN MGNGGNGCNGAYAARGCNAARCCNCCNGCNTCNCARACNCCNGTNATHACNCAYGARATH GTNCCNGGNAARTTYAAYGARAAYGAYTGGAAYGTNATGYTNGARMGNGAYGGNGGNGAR GAYTTYGTNYTNGARATHATGGAYGARYTNATGGARAGYACNATGAAYACNATHTAYGAR AARTAYATHGARMGNCARYTNYTNCCNTTYACNATHACNCARGCNMGNGAYGCNATHATH GARATHATHGARTGGCARTTYYTNGCNMGNGAYGARGGNGARAARGAYATGACNACNAAY YTNGGNTGGACNCARGAYGARGARCCNGARCCNTCNGARACNGAYTGYTGGGCNCARGGN TCNGTNCCNAARAAYATHYTNTCNGCNCCNACNCCNGARYTNGARAARATHCARGARGAR ACNGARGARATHACNGARGARAAYYTNGTNACNYTNAGYATHAGYGAR------------ GARACNGCNYTNCARGARCCNCCNGARYTNGARGAYGTNGTNTCNGARACNGAYATGGCN ACNTCNATGGGNGAYACNGAYCCNMGNTTYTCNYTNGARGARGGNGCNAAR--------- ------------TCNYTNGTNCCNMGNTCNAARTTYAARCCNTAYMGNGGNAARYTNAAR TCNGCNGGNGTNTCNAARATGACNGARACNYTNGARGAYACNGARATHAARATGATHTAY AAYGARATHGTNGCNTCNYTNCCNCCNAAYGARGARAARCCNAAYACNYTNYTNAAYATG CCNGCNTCNTGYTCNAGYATHYTNAARGTNCARACNGGNMGNCCNCCNGGNAAYAARGAY GTNATHTAYGAYGARATGGGNAAYGTNGTNGCNGTNATGAARYTNGAYCCNGARAARYTN CCNACNCAYAARGTNAAYGTNAARTAYCAYGTNGTNGAYCCNGCNGTNGARGCNGCNCAR GCNMGNYTNGAYGCNATGMGNAARGGNAARTCNACNGGNAGYMGNATHAARAARGCNAAR TCNAGYAARAAYTAYGARTCNACNGCNAAYACNGCNACNTCNAARATHAARGGNYTNACN ACNACNTCNGCNGTNGCNCCNYTNCCNCCNCCNYTN------------------------ ---------------------------------ATHGARGARATGGARGTNGCNAAYGGN GTNGTNGTNMGNGARGGNGGNMGNGTNMGNAARGGNCCNGGNMGNTAYTAYMGNAARYTN GAYATHYTNGARGAYCAYCARAARGGNATGAARCCNGTNGCNGTNMGNYTNACNAAYTCN GGNATHACNGTNAAYGAYATHYTNGAYMGNAAYACNCCNATHYTNMGNCCNYTNACNGAY ACNTCNCCNYTNCCNCCNATHATGTCNCARCCNCCNMGNCARYTNCAR------------ ATGATHMGNGTNGGNGTNATHGGNGCNGGNGTNGTNGGNYTNAGYTCNGCNATHAAYGTN YTNGCNTCNATHCCNAARGCNTCNGTNMGNATHATHNNNGAYNNNATHGGNCAYCARACN GTNAGYTAYGGNGCNGGNGGNYTNTTYMGNCCNGAYATGGAYAARYTNGTNGAYCARTCN AAYTAYGAYATGATGGARCARTGYGTNMGNGAYTCNTGGCAYCAYTTYGTNGGNYTNGCN ATGTCNGARAARGCNCARGARAGYGGNCARATGYTNGTNCCNGGNATHGTNGGNCAYMGN AARTCNATGGARAARGCNTAYACNYTNATGMGNGARYTNGTNTTYAAYTTYMGNCARYTN ---AARGARGARGARATHAARMGNATHTAYCCNGARGARTTYAARTAYGCNTAYAGYTAY ATHACNGTNGTNTCNCARGGNAAYGCNTAYATGGAYTGGYTNTAYAARYTNTTYATHTCN AARGGNGGNAARGTNGARMGNMGNACNGTNAAYAAYATGAARGARYTNTAYGGNCARTAY GAYGTNATHATHAAYTGYTGYGGNYTNMGNGCNATGACNTTYYTNGGNGAYAARAAYTGY TTYCCNACNMGNGGNCARYTNGCNYTNGTNAARGCNCCNTGGTTYAARCARTTYCAYTAY YTNGAYACNGAYGTNTAYGTNATHCCNCAYATGGAYAARGTNTGYGTNGGNGGNATHMGN ATHGAYGGNGAYGGNGAYACNACNGTNAARCCNGARGTNACNAARAARATGYTNAARAAY GCNGARGCNATHTTYCCNCARYTNAARGGNGCNGARYTNYTNAGYGARTGGGCNAAYTCN MGNCCNGGNMGNACNTCNATHMGNYTNGARCARGARGTNATGGAYTTYGGNGARAAYMGN AARYTNCAYGTNGTNCAYAAYTAYGGNCAYGGNGGNCAYGGNGTNACNYTNAGYTGGGGN ACNGCNGTNTAYGCNACNAARYTNGCNAAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNTAYCARGTNATGTCNYTNATHGGNGTNGCNCAY---ACN TCNTCNAAYCCNYTNGTNCAYGARGARGGNMGNGARYTNGGNGGNGCNATHATHATHYTN ACNTGGACNGGNYTNTCNMGNTTYTCNTCNYTNTGYTGYACNMGNCCNTCNAAYAAYTAY ACNTCNGCNGTNGGNYTNYTNYTNYTNGGNYTNACNYTNGGNGTNGCNCCNYTNYTNATH TGGTCNYTNTGYTTYGTNAGYGAYTGGCAYCARMGNYTNGGNCAYTGYTCNGGNATGTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARMGNTTY MGNGAYMGNGAYTCNYTNGCNTCNCAYATHAARACNCAYACNAARGARMGNCCNTTYCAR TGYGARGTNTGYGARMGNTGYTTYMGNCAYMGNGGNGAYYTNAAYCARCAYATGAARACN CAYCCNAARGARGCNCCNTTYAARTGYGAYGGNTGYGARMGNAGYTAYMGNMGNAAYCAR GARYTNCARMGNCAYGTNAARAARCAYYTNGAYYTNAARCCNTTYAGYTGYCARATHTGY GGNMGNGGNTAYYTNGARAARTCNGCNYTNGCNMGNCAYGTNTTYACNCAYTCNGARACN AARGCNTTYCAYTGYTCNGTNTGYGGNAARGCNTTYAARCAYCCNGAYCARGTNAARMGN CAYATGGTNGTNCAYACNCARGAYATGMGNTAYYTNTGYACNATHTGYCARMGNMGNTTY AAYCAYMGNAARAGYYTNACNTAYCAY------------AAYTTYCARMGNATHAARMGN CCNACNGAYGAYAGYGAYAGYGAYGARGARTTYGGNAARGGNAGYGGNATHAARGTNGAY AARAARAARYTNCARCARYTNAARGARATGTTYCCNAAYGCNGAYGTNAARAARATGAAR ACNGCNYTNTTYGCNTAYGGNAARAAYTTYGAYMGNGCNGTNGARTAYATGTCNGARMGN GCNGTNGGNAARMGNCARGCNACNGAYGARGAYGAYGAYGARYTNCCNAAYATHACNGCN AGYMGNAARMGNATHAARATGATGCCNCARACNCCNTCNCCNACNAARGARAARGARTTY AAYYTNACNCCNTCNAARGARAGYGAYGARAAYACNGTNGAYTTYYTNAARAAYTGYTTY CCNACNAARTCNGARGARGAYGTNAARAARGCNYTNMGNGAYAAYAAYGGNGAYGTNGAR MGNGCN---------------------------------------------TCNTGYACN YTNGCNATGAAYAAYAARGCNTCNGARAARCCNATGACNGARAARTCNAARYTNATGAAR GCNAANNNNNNNNNNAARCARMGNATGGARGAYGTNAGYGAYGAYGAYGAYGARTAYAGY GAYGARTAYGAYAGYGCNGAYAGYGARGAYAGYGARGAYYTNGGNAAYAARACNACNAAY GARATHGARYTNCAYYTNCARTTYTTYGARGARGCNACNYTNGARGARYTNACNGCNATG CCNGGNTGYTCNAARAARAARGCNGARACNATHATHGGNYTNMGNCCNTTYAARTCNTGG GAYGAYYTNTGYCARAARTTYGAYACNGTNAARCCNYTNTCNACNGCNYTNYTNTCNGGN TTYAARGARATHATGMGNGTNMGNAAYATHATHMGNMGNYTNATGATGMGNTGYGARAGY ATGTCNCARAARATGGARAARGTNGTNTCNACNYTNACN---GGNCCNAGYTGYGARGAR YTNAGYGARTCNGGNAGYYTNGTNMGNCARCCNGGNYTNYTNAAYAAYGARTTYACNYTN AARCARTAYCARYTNATHGGNGTNAGYTGGYTNMGNYTNATGCAYGARCARGARYTNAAY GGNATHYTNGCNGAYGARATGGGNYTNGGNAARACNATHCARGCNATHTCNTTYYTNGCN CAYYTNYTNGARGGNGGNGARGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GAYTTYAAYATGGGNATHYTNGARGTNAAYAARCCNYTNGARTGYGGNTGYCARCAY YTNYTNACNACNTCNAAYYTNGTNYTNAAYGGNTGGYTNMGNAARMGNAGYYTNMGNAAY AAR------YTNATHACNYTNAAYTGGCCNCARGTNTAYGTNGTNGTNTCNAARCARTGY YTNTAYTAYTTYTCNAGYGARACNTCNAARAARCCNTCNGGNTCNATHTCNYTNTAYGGN TTYAAYAARATHTGYMGNGCNACNGGNGARAARGTNAARGAYGTNGTNTGGGCNTTYAAR YTNGARCAYATHCARCCNAGYGTNMGNTCNYTNTAYTTYTCNGCNTCNTCNGARAARGAR ATGGTNAARTGGATGAARGCNATHAARCARGARATGYTNACNGCNAAYGGNAARGGNAAR MGNACNTCNGCNGTNGAYTCNCARTAYGGNGARTCNATHGCNTCNGGNGAYTCNTGGAGY TCNTCNGARTAYAAYGCNYTNGARAARAGYATHTAYGARGARCCNGTNTGYMGNMGN--- ---------YTNTCNAAYTTYACNGAYMGNACNGARTCNAARGAYGAYGGNGARGARGAR GARGARGGNTTYCCNTGYGAYCARTAYGAYCCNGTNAAYTTYGARCCNGGNTCN------ ------------------------------TAYTCNGTNGARCAYGCNGTNTCNGAYTCN AARGARAAYGCNGARTAYTGGAGYGCNGTNAAYTAYCAYGGNTCNAARGARYTNGCNTCN GARATHYTNAARAARATHTCNCARGAYGGNGTNTAYYTNGTNMGNAARAGYGAYGAYGGN TCNAAYGTNYTNGTNGTNTAYTCN---AAYATHAARAARTTYAARYTNATHGARCARGAR TCNGGNAARTGGACNYTNTGYGGNGARGARCCNAAYTTYAAYAARATGGARGAYYTNYTN TAYTAYTAYTAYAGYCAYAAYYTNCCNAARATHAAYCARAARYTNATHTGYCCNTTYCAR YTNCAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TCNGAY YTNACNCARGARTTYATHTAYCCNGAYTGGGCNAARTGYGAYACNTTYTAYAARTGYCAY MGNGGNGTNYTNACNYTNGARTCNTGYMGNTCNGGNGTNTAYAARTAYTAYAAYCCNMGN ACNTTYAGYTGYGARGARAAYCCNTCNGCNACNAAYATHTGYYTNMGNMGNYTNMGNACN ------------------------------------------------------------ ------------------------------------------ATGGCNGAYACNAARTCN AGYYTNGCNMGNGAYGGNACNATGCARGTNACNGCNAARGARGGNATHGAYTAYYTNAAR TCNGCNAAYAARGAYACNYTNYTNAARGCNCARGGNYTNGTNAARGAYAARCARGCNGTN CARMGNGAYGGNACNATGGTNTCNACNGCNAARGARGCNGARMGNYTNYTNGAYGGNAAY AARCCNGAYGCNGAYGCNCARACNMGNGGNCARCARAARCARATHGAYGARYTNAARAAY GARAARACNGARCCNAARGCNAARAARGCNAARYTNGCNAARGAYGGNACNATGGTNGCN ACNGCNAARGARGCNAARTCNYTNYTNGCNGGNGARAARYTNAGYGAYACNMGNCAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CARGARGARAGYYTNMGNCARAGYATHACNCCNTCN---AAR AAYACNYTNMGNAARCAYCARYTNGTNGARGGNGAYAAYGGNGCNMGNACNAGYCCNAGY MGNTTYGAYGTNGAYGGNTCNTAYATGAAYCARCAYMGNGGNAGYTTYAGYTCNGAYCAR AGYACNCCNCCNGARAGYCCNMGNAAYAAYCAYCARTTYCARYTNTCNTCNTCNAAYGAY GGNMGNCARACNMGNACNATHCCNTCNACNCCNGGNYTNCARTAYMGNTCNCAYAAYTCN AGYGAYTCNAGYYTNGARMGNCAYAGYGTNGAYACNAAYGGNAGYGAYGAYGCNATHYTN GCNCCNGARTCNATGMGNGCNCCNGCNTCNMGNYTNCARCCNCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGCCNAGYYTNCCN YTNGTNAARCAYACNATGGCNGCNGTNGGNTCNAGYATGGCNMGNTCNGTNATHAARGCN ------------------ATHATHAARCCNCAYATHCCNATGATHAARTTYCCNGTNMGN GCNCCNACNTCNGGNGCNTCNTCNGCN------AAYATHACNAAYCCNAAYTCNYTNGAY TCNYTNGTNTCNCARACNATGACNTCNAGY---------TCNAARCCNAGYGCNGTNAAR TCNAARGGNCCNYTNATHGAYTCNAGYGAYYTNCCNATGAARTAYMGNMGNAARCCNATH TCNAGYGARGARATGGARTTYATHGARAARGGNGGNCCNGTN------------------ ------------TTYGCNGCNGCNCARTGYYTNGARAARMGNCARCARATHGGNATHTGY GTNGARGARTGYAGYATGCARGCNTAYACNAARAGYCCNGGNCARTGYCCNAAYGGNCAR GTNTGYGCNTCNAAYGGNTGYGGNCAYACNTGYCAR---------------CCNGCNCCN CARGCNACNAARTGYTCNGGNGTNATGTGYGCNATGTAYTGYGARAAYGGNTTYGCNGTN GGNAARGAYGGNTGYCCNATHTGYAARTGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNCARTTYCAYTCNCARACNTGYCCNYTNYTNTTY MGNGCNACNGAYAARYTNTGYGGNGARCCNATGAARAARMGNAARAARACNGAYCCNGCN ATGGCNGCNGCNMGNACNCARAARAARATGAARMGNATHGAYAARGARATHAARMGNYTN TCNAARTTYGGNAARATHYTNAARCCNGTNGAYGARATHGARGTNGAYMGNMGNAARYTN ATGGCNTCNGGNGARMGNAARMGNGAYCCNGCNGTNYTNACNTTYGARGARTCNGARTCN MGNGCNYTNYTNCAYAARCARTGGAAYAAYTTYTGYAAYAAYMGNTAYAGYGARMGNGTN TCNACNTTYTTYAARATHGTNGARGCNCARGARGARGCNYTNAARGARYTNMGNGCNGAR TCNGARGARYTNTAYYTNGCNGCNATHCARAARGAYGAYAGYYTNYTNCCNYTNAGYTTY GARGGNCCNAARGARACNCCNCCNATHAARGGNTAYGCNGCNCCNGAYGGNGARTAYGTN GAYACNACNMGNAARTTY------------------------TGGAAYATHGAYATGGAR GTNAAYYTNTTYCAYGCNATGMGNGGNCAYAARCCNGCNGGNGTNAAYMGNCAYTTYCAR ATGATHGCNATHCAYGAYAARYTNAGYTCNTCNTCNAARAARATHACNTCNGGNGAYGTN TGGAARCAYYTNACNACNYTNTAYGAYYTNCARGCNYTNAAYGARTCNGARATHGTNCCN TTYCCNAAYAARGGNGGNGAYTTYTCNYTNAAYGARAARGARATGGTNGAYATGTGYTCN AARTCNTTYCCNMGNTCNTCNTAYATHACNACNGCNACNAGYGAYTCNACNAARGCNGAR GCNGTNGGNAARAAYATHTCNAARYTNAAYGCNAARYTNGARACNAARACNGGNTCNCAR ACNCCNAARCARGARTCNAARTCNGARCARAAR---YTNATHGCNTCNTAYAARGTNGAY AGYMGNTCN---AGYACNCCNAAYMGNACNGAYTCNAARTCNTCNAAY------------ ------------CAYAAYTCNACNAAYAGYTCNCAYCARACNACNCCNTCNTCNGCNCCN TCNCCNTCNCCNAARMGNACNAARMGNACNMGNAAYGTNAAYTCNGTNACNGCNAGYCCN GCNACNCCNACNGARCCNCARGCNAARMGNMGNMGNATGAARGARGARTAYTGYGGNACN YTNGTNTAYATGGCNCCNGARATGAAYTCNACNTAYTCNTAYYTNGTNGAYGTNTGGGCN ATGGGNATHATHATGTAYTAYYTNYTNACNGCNTAYCCNAARGAYACNGCNYTNAAYGAR GAYATHAARAARCAYGGNCCNGARTTYAARGARCCNCARTGGGCNGCNGTNAGYGAYCCN GCNAARGAYYTNYTNMGNGARATHYTNACNCARGAYCCNGCNCAYMGNATHTCNTCNGGN GARGTNYTNAAYCAYGARTGGTTYACNGGNAARAARMGNGARCAYCCNAAYGTNYTNAAR YTNATGAARGARTTYMGNCARGARCARCARGCNGAYYTNAAYGGNGCNATHAAYGGNACN TGYCARYTNAGYGTNGGNGAYCCNCAYYTNGAYCCNGCNTGYTGYYTNTCNGARGAYACN ACNAARAAYGGNTCNGGNGGNAARAARAGYGGNGARACNAGYCARAGYGGNGCNCCNTCN CCNMGNYTNTCNAGYAARACNCCNACNAARACNAGYMGNYTNGGNTCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARAARTCNTTY TCNAGYATHCCNAARTGYTTYTGGTGGAGYGTNATHACNATGACNACNGTNGGNTAYGGN GAYATGTAYCCNACNACNAARTGGGGNTAYYTNATHGGNACNGTNACNGCNATHTCNGGN YTNYTNATGGTNGGNTTYACNGTNCCNGTNYTNGTNAAYAAYTTYATHYTNTAYTAYAAY CAYTCNGARTCNCAYATHGARMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GCNYTNCARGAYMGNYTNAARCARTCNGARTCNMGNYTNTCNGAYTTYMGNAAYCAR TGYCARYTNYTNMGNCARGARYTNAARGTNGCNAAYAARGTNYTNTCNCARGARATHGGN GARAAYGTNAAYATHCARTCNYTNYTNAAYGARACNAGYCARTGGMGNGGNMGNGCNCAR CARATHATHGCNYTNCARCARAARGTNGARGARYTNAARGTNMGNTAYGARAGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TGYTCNTCNYTN AAYYTNGAYTAYGARATHGAYTTYTGYYTNCCNGTNGARATHGAYGTNGARCARAAYGAR TTYACNATHAGYAGYGGNTGGATHGCNGGNGTNTTYTTYYTNGGNYTNTTYYTNGGNATH GGNYTNGTNYTNYTNYTNGCNMGNCCNTTYYTNAAYGCNTGGGARAARAARAARYTNCAR GAYGARGARAARATGYTNGAYGTNACNAARGGNGARGTNATHACNGCNGAYTAYAARAAR GARAARGAYGAYGGNAARAARGGNAARAARMGNAARAARTCNAARGCNGGNAARGARAAR GTNGCNGTNATHAARAGYAARTCNMGNTTYTGGMGNMGNAARCCNAARGGNGCNGCNGAY TCNAARGARGTNAARGARGGNGAYGTNGAYCCNGCNTAYGCNMGNGGNATGGTNGARGTN ATGYTNCARACNACNAGYAAYGGNGARGAYGTNGARATGGCNGAYCARGAYATGATGAAY ATHYTNTCNATGGARMGNGGNATGGARGARCARAARTCNACNYTNTTYYTNAARACNYTN GCNYTNYTNYTNMGNAARAARGTNGARAARMGNGARATHACNCARAAYTTYTAYGARAAY TTYYTNAARAARACNGARGARGAYATGAARGAYATGGGNACNATGATHGAYMGNGARAAR GARGARGCNGARGARAARYTNAARAGYGAYCCNAARYTNAAYAARGAYACNCARACNYTN GARACNGARATGCARAARYTNCARACNGARTTYAAYAAYAARCARACNAARYTNCARMGN GARTTYMGNGAYAARGTNMGNTTYGAYYTNYTNMGNTCNTCNGGNATGCCNGARAAYGAR GTNGARAARGTNATHTCNAAYYTNATGTCNAAYATGGCNYTNGTNGARGARAARYTNGGN YTNGARCARGCNMGNCARMGNMGNGCNYTNGARCARMGNYTNGCNAARMGNAARCARGCN YTNGARTAYCARGAYATHGARAARGARGARAARAARCARGARGARGARGCNAARGTNAAR GTNYTNMGNTCNYTNYTNGAYAAYCAYYTNAARGAYGGNTCNYTNYTNGARCARCARCAR GAYTCNATHATHTCNGAYTAYGARAAYGARYTNAAYGTNYTNAARAARTAYCAYGCNGAY GARTTYAAYCARYTNMGNYTNGARAARTTYGARATHYTNCARCARGAYMGNYTNAAYAAY TTYTAYAARYTNAAYMGNAARCAYGAYAARGARAARTCNGCNTTYYTNCARACNTCNGAY AARGCNACNAAYCCNCCNGARTTYATHAARYTNTAYCAYGAYYTNATGACNMGNCARAAY ATGGARAARGARGCNYTNTCNGGNGAYYTNGAYATGMGNGARATHCARGARATHTAYAAR YTNAARGARGARATHGARAARAARGARTCNMGNGCNACNCAYCARGTNACNGAYAARYTN TCNGARCARATHGARGGNTCNTCNAAYATHACNTCNAARGARGCNGCNAARYTNATHAAR ATHCAYAARGCNGARATGGARAARTAYCAYGCNAARAGYCARMGNAAYAARCARGCNATG YTNGCNMGNYTNCARGARAARYTNCARCARMGNYTNGARGCNGCNGAYGARGCNGARGCN MGNGAYCARMGNGARCARGARGCNYTNAARGARCARCARATGGCNACNYTNAAYAARGTN YTNGCNACNAAYYTNGAYATHACNGARGARGCNAARCARAARATHYTNCARGARCAYGAR CARAAYATGCARAGYYTNTCNAAYCARYTNGTNMGNAGYAARYTNMGNCARCARAARAGY YTNGARATHAARYTNAAYCARAARAARGCNAARYTNGCNGARYTNAARAARAARMGNGAR GARCCNMGNCCNGGNAGYAGYAARAARGARAARTCNAAYATGGARAAY------ATGGCN ACNAGYYTNGAYGARCARATHGCNAARGARGARTCNAGYTTYGARGARGCNMGNCARGCN GCNGTNGCNGARYTNMGNAGYCARYTNGCNMGNGARACNGARGARGCNYTNAARCARCAR GAYGARGARATHGGNYTNYTNATHGGNMGNYTNCARGTNGGNCARGCNMGNMGNAARGCN GTNYTNGARAARCARGAYGCNGTNYTNAARGARYTNCARGAYAAYYTNGARMGNCARGTN TCNTCNGCNGGNGGNTTYCARCCNTCNATHACNGAYTCNATHYTNAAYCARTAYCAYGCN AAYTCNAAYTAYYTNAAYGARMGNYTNCARMGNCAYMGNGAYGARCAYCARMGNMGNATH YTNCARAARYTNGCNTAYAARMGNGARGARAARGARCARGARATHGARTCNCARYTNGAR GARCARGCNCARACNGARTAYTCNGARAARCARMGNMGNGGNGCNGGNTAYGCNAGYYTN GCNYTNATGCARTCNTTYYTNGARCARMGNCAYAARAARGCNYTNGARGARYTNGARYTN GARATGAARACNGARYTNGARAARAGYAARACNGARYTNAAYACNCARYTNGARTCNGAR YTNMGNAAYGARYTNGAYACNGARMGNCARAAYYTNYTNGTNCARYTNGCNGCNGTNAGY GAYATHTCNCARGCNGAYYTNCAYACNGCNGTNAAYGCN---------GGNAARGGNGAY GTNAARGTNGCNAARAARATHGCNAARGAYYTNAARGARAAYGTNGARMGNGCNAARTCN GCNYTN------TCNAARTAYGGNCARATGGAYGAYGAYATGGGNTAYMGNMGNGCNMGN TCNGAYYTNGARTCNAAR---------ACNMGNTCNAARGARMGNACNGGNTCNGCNGTN ACNTTYTCNAAYMGN---AARGCNMGNCARGCNTTYGTNGAYGARGAYGARTCNGAYGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GGNAARCAYATGTCNGTNAARYTNGCNATHCARGTNAAYATHTAYGAYGCNAGYATHACN TGYAAYGAYACNGAYGCNTTYGTNGGNAARGCNAAYCCNGTNYTNACNTGYATHGTNAAY CAYACNAAYYTNCARGTNGAYGGNTTYTCNTTYCARATHGGNGAYACNGGNGARATHATH MGNGARGGN---GARAARAAYGCNGARCAYATGTTYGTNAAYGTNACNAARGTNAARGAR GGN------ATHAGYYTNGTNTCNYTNGAYYTNCAYYTNGCNAARCAYGARYTNYTNGAY AARAAYTAYTAYGTNYTNATHGAYATHAARGGNGGNCAYACNAGYAARGARAGYGTNMGN YTNAAYAARGTNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GGNGAYCCNMGNMGN MGNAGYAGYCARACNTCNACNCAYAGYGARCARYTNCCNTTYGCNGTNATHAAYMGNAAY GTNATGMGNMGNGAYTCNTTYGARATGCCNCAYMGNACNATHATHGAYTCNCCNMGNCCN ACNMGNTCNMGNTCNYTNCAYAARTCNCCNGTNGAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGGYTNGAYAARYTNGGN YTNTCNGCNAARTAYGGNGTNTCNGCNGTNTTYMGNCARACNTTYYTNGGNGGNAAYTAY GCNYTNATHTCNMGNAARATGGARCCNAAYCCNGAYTAYTAYYTNACNGTNYTNTTYAAR MGNYTNATHGARGGNAAYGTNTTYAAYGCNACNGTNYTNCCNGARAAYAARTAYYTNMGN YTNTAYGCNCAYTGYACNAARCARTCN---GARYTNTAYAARAARGGNGCNYTNACNYTN GCNTAYYTNAAYACNAARAAYGARTCNATGAARATHAARYTNCAYCARTTYTCNGCNYTN CCNYTNCAYYTNTAYATHYTNACNCCNGGNGAYGTNCARGGNYTNAARTCNAGYTAYGTN MGNYTNAAYGGNAAYGTNYTNCARATGTCNGGNTCNGCNYTNCCNCCNYTNCCNCCNAAR ATHTGGAARGAYGCNGTNAARATHCCNCCNYTNTCNTTYGGNTTYATHGTNATHCCNGAY GCNAARATHYTNACNTGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GCNAAYGTNAGYYTNCCNGGNYTNYTNYTNAAYCARAAYGCNGTN CCNGGNACNGCNATHCCNTCNCARCCNACNYTNCCNCARYTNGCNCARCCNTCNACNTCN GGNTCNTCNGTNCCNTCNGCNCCNYTNGAYATHAGYAGYYTNYTNAGYAAYYTNATHAAR GCNGGNYTNATHAARAARGAYGAYCCNCCNACNAAYCARGTNGCNCCNTCNGTN------ ---------ACNCARCARYTNCARAARGCNAARATGGARGARCCNGARGARACNAAR--- ------------AARAARMGNGAYATHYTNCCNGAYYTNTCNGAYTTYGAYTCNGAYYTN YTNMGNATHACNTAYAARAGYGTNGTNGARGAYYTNCAYGARGGNATHCARTGYCAYACN TGYTCNACNMGNTTYACNTCNGARGAYAAYGAYAARTAYMGNGCNCAYYTNGAYTGGCAY TTYMGNCARAAYAARYTNGARCARGAYATGTTYAARGTNGCNAARAAYMGNAARTGGTTY TAYCCNATHGCNGAYTGGATHCARTAYGARGARYTNGARGAYATHAARCARACNTCNMGN AGYATHATHTTYGARCARATGAARTTYGGN---------AAYCARAGYCCNGGNATHGAR CAR------------YTNMGNGCNYTNGAYGGNAARGARGTNYTNAARAAYCCNGTNGCN TCNGGNGTNGARGGNGARGAYATHTGYGCNACNTGYGGNGAYCCNTTYGAYCARYTNTGG AAYGARGARAAYGARGARTGGATHYTNAARAAYGCNGTNAARGTNAAYGGNAARACNTAY CAYCCNATHTGYTAYGARGAYATGCARGARACNCCNACNCCNGTNCCNGGNGTNGAYGCN AAYCCNYTNGAYCARGARATHGCNTCNATHAARGARAARGARGARGARGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARTTYACNGARGARGARATHGCNAAYGAYCCNTCNAARMGNATGYTNTGG GCNGCNGARAAYAAYAARGTNGAYATHGTNGARGARYTNYTNAARAARGAYCCNCARYTN GCNYTNGTNAARGAYAGYGAYGGNTAYACNCCNYTNCAYMGNTCNGCNTAYAAYAAYCAY GTNGAYATHGCNAARYTNYTNYTNGCNCAYCCNGAYTGYATHCAYGCNAAYACNGTNGAY GGNTGG------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TAYTAYYTNGARGCNMGNATGGGNCARCARTAYGGNGAYTCNAAR GAYGTNTTYAARACNAAYATHAARYTNAARGTNGARGTNGAYCAYYTNTCNGARCARYTN GARGARAARCARATHTAYYTNAAYAARGCNGCNCARGCNATGAGYACNATGACNTCNAAY CAYCARCARGCNGARGARGCNGTNMGNCARCARTGYAARGCNGARTAYAGYMGNGARYTN GCNGARYTNMGNAARGARYTNAAYAARGCNYTNGARGARTGYGARGAYAGYMGNAARCAR GCNGARGAYGCNAGYCARGARCARYTNAARACNGCNATGGARGCNYTNGCNAGYAGYGAR ACNGCNGTNGARGARYTNCARATGCARYTNAARMGNGARMGNGCNGARTTYGARAAYAAR YTNAARAAYCARGCNGCNYTNTTYAGYGAYAARGAYAAYGAYGARATGMGNGCNYTNAAR CARCARYTNTCNGAYYTNCARAAYAGYYTNGCNGAYCARAAYGTNAAYATGYTNGCNYTN CARMGNGARYTNGGNGAYYTNGAYMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TTYGTNGGNYTNYTNTCNAARATGAAYTGYCCNTCN CCNAAYGARGARACNGTNTGGAGYTTYTAYATHGTNTAYAGYCARGCNGTNATHGAYCAR TGYAARGAYATGYTNCARTTYGCNGARAAYATHMGNGTNACNGGNCCNTCNTCNTAYYTN CAYYTNYTNCARGARGCNCAYYTNYTNYTNAAYACNTGYATGATGCAYMGNAAYGARAAY GAYTAYCARYTNGAYAARYTNYTNACNAARGTNMGNMGNYTNYTNGGNGAYATGTAYGCN YTNCCNGGNGCNGARGGNTGGMGNYTNTGYTAYACNCAYTAYAAYAGYYTNGGNATHAGY ATHGAYAGYATHGTNAARCARGCNYTNGARCARGCNAARAAYCARAARTCNATHCARTTY GGNAARGGNYTNATGGAYTTYYTNAAYCARMGNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARATHGAYYTNGTNGARYTNMGNAARMGNYTNCCNAARMGNYTNYTNTAYATHYTNMGN TAYGGNGCNGTNAARGARGGNYTNAAYGTNGAYTGYCAYGGNTTYGTNGAYATHAARGAR YTNCARACNATHTCNYTNYTNAAYTGYTAYTCNGARGARGARATHYTNCAYGARGTNAAR AAYTCNGTNTCNTAYMGNAARGTNAAYMGNTAYGAYTGGAARGARMGNGAYAARAARATG TAYGTNMGNGCNTCNTAYYTNMGNMGNTTYGARCCNAGYCCNTTYCAYGCNGGNTCNAAR GTNAARACNYTNCARGARTCNAGYATGACNTGYATHYTNGAYAAYYTNCARATGTTYGAY YTNGARGAYTTYCARGAYGARTAYATHATHAARMGNATGATHCAYMGNYTNAARMGNGAR AARAAYYTNTCNAAYAARGCNYTNTCNGTNYTNYTNGTNCCNACNYTNACNMGNATHGAY YTNGARGGNATHTAYYTNACNAAYAARTCNYTNMGNATGYTNTGGACNCARTGYCCNCAY YTNAARGGNATHAGYYTNAARAAYTGYGGNTAYATHATHACNGAYACNGTNYTNGCNCAR YTNGTNAARAAYATHCCNACNATHGARCAYYTNAAYYTNTCNMGNTGYAAYCAYYTNACN GARAARTGYYTNCCNATHYTNGCNAARMGNYTNCCNAAYYTNAARATHYTNMGNYTNGCN GGNGTNTCNGCNATHAARCCNCCNAGYGTNYTNTCNTTYATHAARTCNGCNAAYGARYTN ACNYTNYTNGAYGTNTTYTAYATGMGNACNAAYTCNCARCARTAYAAYAGYYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNCCNTAYYTNGGNAGY AARATHAGYYTNATHTCNAARGCNGARATHMGNTAYGARGGNACNYTNTAYACNATHGAY CCNAAYGARGCNACNGTNGCNYTNGCNAARGTNMGNTCNTTYGGNACNGARGAYMGNCCN ACNGAYMGNCCNYTNCCNGCNMGNAAYGARGTNTTYGARTTYATHATHTTYMGNGGNCAY GAYATHAARGAYYTNCAYGTNAGYGARGGNCCNAARTGYCARCARATHGAR---GGNGTN YTNTCNGAYCCNGCNATHGTNAARTCNTCNCARCCNCCNCCNGGNCCNACNGGNGCNGCN TAY--------------------------------------------------------- ------------------AAYCARGGNCARCCNCCNCARGGN---------CAYCCNCCN CARGGNCAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TTYTAYAAYGCNTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CCNGCNGAYYTNGARGTNTCN TAYGAYGARTTYAARCAYGTNGARGCNYTNYTNCCNAARACNACNGTNCCNAARYTNCCN CARCAYACNTCNTAYCCNACNCCNTCNGGNTGGGTNCCNCCNAAYGAYGARYTNMGNAGY CARCAYCCNTAYYTNGTNMGNMGNACNAARAAYCAYGTNATHCCNGTNTAYGCNGARCAR AARGARGTNTGGGGNMGNATHATGCAYCAYATHGTNGTNAARGGNATHGARGGNGAYATH TGGAARYTNGARTCNGARYTNMGNCAYTTYYTNATGGARAARCAYGGNYTNGARTCNYTN AAYACNCARGTNCAYGARGTNAGYMGNACNGTNMGNGTNMGNGGNATGTAYCAYGCNGAY ATHGCNCARTTYYTNYTNGAYMGNGGNATGAARAARAAYGARYTNACNAAYGAYATHGCN GGNGAYYTNGARYTNTGYTAYGCNCARYTNCAYCCNAARAARAARYTNTGGAARGCNTTY AARYTNATHGGNTGYAAYAGY---AAYATHGAYCCNMGNATHYTNMGNTCNMGNATHATH MGNGARGTNCARTCNAARTGGAARGAYGGNGTNATHTCNGGNAAYATHGGNCAYTAYGGN GGNGCNGTNTGGYTNMGNYTNCAYTTYGAYACNTCNATHCARMGNMGNAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TCNACNGGNAGYCCN AGYACNMGNTCNATHATHGAYTCNGTNCAYAGYGGNTGYTCNAGYGCNGARMGNAARGAR MGNYTNYTNTCNGCNATHGARCARAARGTNCARATGMGNATGGCNTCNAGYCCNGCNAAY GCNATHAARACNAARGCNAGYCARATHCCNMGNTTYATGGCNTTYYTNGCNAARAARAAR GGNGARACNGCNAAY------ACNCCNGGNAGYAARAARTGGAAYAARATHCAYCARAAR GARTTYGCNAARTTYGAYTCNATHGAYGTNTAYYTNGAYAARAARATHCARMGNAARGAR AAYYTNTCNGCNAGYTCNAARAARACNYTNCCNCAYAARTCNCCNGCNGTNAAR---CCN MGNGTNAARATHGTNAARCCNGTNACNMGNAAYCCNGARYTNCCNAARGTNTTYAARCCN ACNGTNATHTCNACNAARAAYATHAAYTTYGAYTTYTCNAARACN---GCNTCNGAYTCN AAYAARACNCCNGCNAARACNAAR---------YTNAAYTTYACNCCNTCNMGNAARGCN TCNGCNACNAARAARYTN------------------AARGARATHGGNTCNAAYGCNAAR GCNTCNCCNTTYACNTTYACNGGN------------AAYTCNACNTTYAAYGTNACN--- AGYTCNAARAARCCN---GTNTTYGAYYTNAARGCNAGYYTNGCNAARCCNYTNACNTGG AARCCNCAYACNGGNAARYTNCARMGNGTNGAYATHAAY------ACNCAYACNYTNATH TCNGTNACNMGNCARACNGTNACNAGYGTNTCNTCNATHMGNAAYMGNAARGCNATGGCN ACNGCNAGYMGNCCNACNCARGCNAARGAYGTNMGNMGNGCNGTNCARATHGAYMGNMGN AGYAAYCARAARTAYGTNGAYATGATGAARMGNMGNGGNYTNATGGCNTTYGTNTAYGAY CAYGGNMGNCAYCAYTGGTCNCARGGNGGNCCNYTNTTYTAYCCNYTNCCNCARYTNGGN AAYTTYCCNAAYCAYCCNATGCARGGNCCNGCNCCNCARTGGYTNMGNGGNCCNYTNATH GGNGGNCCNGGNCCNAAYCARCARTTYGAYCCNMGNATGGARGARATGACNACNATGCAR AARGGNMGNGTNMGNYTNGAYGTNGGNGGNCAYCARGTNAAYCARGARGARGAYGGNACN ATHTTYATHGAYMGNGAYGGNACNCAYTTYMGNTAYATHYTNAAYTAYYTNMGNGAYGGN GGNGTNAAYCAYGAYAGYYTNCCNAARGAYMGNCARGTNYTNAARGARYTNATGTAYTTY GGNTCNAARTTYGTNTAYYTNGGNAAYGARAARGARGAYGARGARGARGTNAARATHTCN GARACNGAYAAYGTNGTNYTNTCNGAYAGYGAYGTNAGYGAYGAYGAYGGNGARACNTGY YTNYTNGAYATHYTNGAYACNGCNGGNCARGARGARTAYTCNTCNATGAARGAYCARTAY GTNMGNAGYGGNAAYGGNTTYGCNATHATHTAYAGYATHACNGAYAARGARAGYTTYAAR GARGCNGARGCNATHTAYMGNTGGYTNAARMGNYTNMGNGAYGARAAYAGYTGYCCNGTN GTNYTNATHGCNAAYAARCARGAYYTNAARGGN------GARGGNACNGTNACNGAYCAR GARGGNAARGAYYTNGCNCARAARYTNGGNGCNCCNTTYTTYGARACNTCNGCNAARGTN GGNACNGGNATHACNGAYGCNATGAARGGNYTNGTNMGNATHATHCCNMGNGARGGNAGY GAYTAYAARATHGTNATGYTNGGNAGYGGNGCNGTNGGNAARTCNAGYATHACNYTNMGN TTYGTNAAYAAYGTNTTYGTNGAYGAYTAYGAYCCNACNATHGARGAYTCNTAYMGNAAR ATGATHACNGTNGARGGNYTNMGNGCNGTNACNAARGAYACNAARAARGCNGCNAARAAR GCNAARAARTCNAARAARAARTCNACNCAYGCNACNAARNNNCARACNAARTCNGCNGGN YTNCCNGGN------------------------GGNGCNYTNATGAAYAGYGCNTAYAAR AAYATHMGNMGNATGTTY------GGNTCNMGNAAYTCNCARTCNTCNTCNAAYTCNYTN CCNYTNCCNGGNTGYATHCCNCCNCCNCCNCCNCCNCCNGTNACNAARAAR------GAR AARAARACNGAYGGNAAYGTNGTNATGYTNTCNATGGGNACNYTNGGNGARGARACNAAR YTNGTNACNGGNGAYCCNATHAARTGYAGYGGNTGYGARGTNGTNYTNACNGARACNTCN ACNYTNGARACNGAYGGNGAYAARAARGTNTGGAAYTGYGARTTYTGYGGNCAYTCNAAY AARAAYYTNGAYATHGARGAYGAYGARATHCCNAARGGNGAYTGYTTYGAYTAYATGYTN TCNCCNGCNACNGARCCN------GARCCNGTNGGNGARGCNGCNGCNGARGARGTNAAR AARGARAARACNACNCCNGGNGTNATHGTNTAYTGYATGGAYATHAGYTCNTCNATGCAR GCNAAYTGYGARATHCCNGARTCNCARACNACNTGGMGNCARGARMGNYTNGGNACNAGY AAYACNAAYMGNGTNTCNMGNYTNGCNTGYATHCARGCNGCNGTNGARMGNYTNGCNGAR CARATGAARACNGAYCARCCNGARAARAARATHYTNYTNGTNGTNTTYAGYTCNCARGTN TAYGTNAARGCNGGNGGNGCNATGGARAAYYTNCCNTCNATGACNGAYGTNGAYAAYAAR ACNTTYGARCAYYTNATHGARCARGGNATHGCNYTNAAYYTNAAYTAYCCNYTNAARTCN YTNGARGARTCNTAYGARGGNYTNGTNGARGCNGTNMGNGGNYTNMGNACNACNGGNTGY ACNGCNYTNGGNCCNGCNYTNTCNATHTGYATGGGNTTYGTNAAYAGYACNCCNGGNTCN GARATHGTNYTNTGYACNGAYGGNGARCCNAAYGTNGGNGTNGGNAGYGGNCAR---GGN MGNGAYTTYTAYGARMGNGTNGGNGAYTAYGCNMGNTCNAARAAYGTNACNATHAAYATH YTNGCNGTNGARGGNGCNTCNGTNGGNYTNCARTCNGTNAGYYTNGCNGCNGARMGNTCN GGNGGNACNACNAAYAARYTNAAYCCNGCNGARATHGTNMGNCARYTNMGNACNATHGCN CARAAYGARGTNGTNGCNACNTCNGTNACNGTNMGNTTYTTYYTNCAYCCNGAYTTYGTN TTYGAYGARCCNGARTAYGGNGAYAAYYTNAGYCARYTNGARAARGARATHGGNTCNGCN MGNAARGARACNGAYYTNACNTTYMGNTTYAARATHMGNGAYCCNTCNAARGCNAAYATH AARGARGTNCCNTTYCARGTNCARATHACNTAYACNMGNCCNAAYGGNATGAARTGYYTN MGNGTNYTNAGYCARAARAAYGARGCNACNTCNTCNMGNAARGAYATGGARGARAAYATH AARATHTCNGTNYTNAGYGTNGCNGCNATGAARACNACNGCNCARYTNGCNAARACNGGN AARGGNGTNGARGCNCARCAYYTNYTNAARAAYATGAARMGNATGGTNCAYMGNGGNGCN AARACNAGYGARCARCARGARGCNMGNYTNGCNTAYGAYAAYGARYTNGARGCNTGGGAY GAYCAYYTNACNTTYCARAAYGAYATHTTYGCNACNATGAAYCARACNGAYATGGCNAGY AAYATGATHCARCARGCNAAYATHTCNTCNGTNMGNACNGAYGTNGGNTCNAGYAARTTY AGYAARGTNAARGCNMGNAARAARATGAAYTCNGCNAGYAARGCNGCNTAYTAYTCNTAY AARAAYGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARAARTTYGTNCAYCCNCARYTNGCNMGNMGNGARAARGAYATHGAYGARATGATHGCN CARGCNAGYCARCARGGNTAYAGYACNYTNYTNTCNYTNGGNTCNAARGGNGTNAAYTAY GCNTCNCARGTNGTNATGMGNACNGCNATHATGGGNCARTCNAARYTNGTNGAYCAYYTN MGNMGNAGYTAYAGYACNAGYGAYYTNACNGAYGAYGGNCARTCNGTNATGCARMGNCAY GARGCNATGTCNGARGARGTNGCNGARGAYGARYTNGAYAAYMGNYTNMGNGARGAYAAY GCNGARATHGARAARMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARACNTCNGARATHACNAARAARATHYTNAARTCN CARGCNMGNGCNCARTCNGGNAARMGN---TCNYTNTAYCARTCNCCNGGNTCNGTNATG ACNGCNCARTCNTCNAARACNGTNMGNGAYYTNGCNMGNAARATHMGNATHAAYCARACN ATGGAYCCNTCNGTNMGNCCNAGYCARGCNGARACNAGYCAY---------------GAY AARCCNCCNCARMGNGCNCARGTNGCNAARGAYGTNYTNGGNMGNMGNGCNACNTTYGGN GAYATHATGAAYCARMGNAARCCNACNYTNAARATHYTNGCNCCNAARACNCARCARMGN CARCARNNNTCNTCNCCNYTNTCNTCNGCNGARCARCARAARGCNACNYTNGARGCNAAR AARMGNATHAAYGARGARMGNCARGCNGGNGTNCARGAYAARGTNMGNGAYTTYGTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CCN GCNGCNGCNAAYCAYTAYYTNCAYTAYYTNAARGARCAYTAYGAYTTYACNCARTAYGTN GAYATGYTNGGNYTNYTNGGNMGNACNGARGARGCNGCNATHTTYAARYTNCARYTNGCN YTNCCNGCNTCNGAYGTNGGNYTNAARATHTCNAARYTNAARGAYTGYCARMGNTCNCAY TTYAGYGCNGAYCCNTCNYTNAGYCAYCARTCNTCNYTNGTNCARGARTAYGTNGAYYTN YTNGARMGNCARMGNCCNATHGARGAYGCNGAYGCNAARCARGARGCNAGYGGNCARAAY MGNYTNTTYAARGAYTTYCCNMGNAARNNNNNNYTNGTNGAYATGTCNGTNATHACNACN YTNTAYTAYTGYTCNYTNTAYCAYTTYGAYYTNACNGARAAYTCNYTNGGNAGYCCNYTN GCNATHMGNAARMGNCAYCARATHTCNGARAARCARTAYGTNTGGACNTCNATHGGNGCN MGNGCNAARYTNMGNCARTGGAARGAYATHGARGCNATHYTNACNACNAARGGNTGGTTY GGNGGNACNAARYTNAARGCNGTNATHGGNTTYGAYAARATHGTNGGNATHYTNCAYMGN TAYAGYGCNCCNCCNGAYGTNYTNGAYAARTAYYTNGCNYTNATGGAYGAYCCNGARCAR MGNYTNAGYYTNGCNCARAARGTNAARTGYCAYAARGCNGTNATHGAYACNTAYGCNTCN YTNAARGAYMGNGCNTCNYTNGARACNTAYGCNTCNAARYTNGAYMGNTAYTCNAARGAY GGNYTNTAYGCNTAYGAYGTNYTNAAYGGNACNYTNGTNAARTGGAAR------------ ------YTNACNACNTTYATHAARGARACNAARCCNACNACNAAYGTNGARACNACNCCN GCNYTNCCNTCNCCNYTNGTNGTNGARAARCARAARGCNATHGTNAARCCNCARGTNATH ACNCAYGTNATHGARGGNTAYGTNATHCARGARGGNYTNGARCCNTTYCCNGTNCARCAR ACNTGYYTNYTNCARGARTTYACNTGGCCNAAYAARGTNAAYGGNTCNGGNAARGARTCN GARGAYGAYGGNACNAGYCAYGAYGARGARCCNCCNACNYTNYTNCCNCARATGGAYACN TGYGTNACNAGYCCNACNAGYCAYMGNTCNGAYGTNTCNGAYCAYATHGCNACNGTNGCN ------------------------------GARTGYGARTCNTGYCAYAARACNGCNACN GTNTCNGCNCARATHGGNTCNCAYTGYTTYTGYTCNYTNTCNTGYTCNMGNMGNTTY--- GTNTCNCAYACNMGNMGNACNGAYYTNTTYAARAGYAARGGNCARTCNAARAARMGNAAR CARATG------------AARGGNTGGMGNTCNGGNAARGAY---GAYYTNTCNCCNTCN TAYTCNATGGTNGARGGNGARGARGAYCARGAY------AAYGCNATGATGCCNATHACN GAYGARATGAGYTGYTGYAAYTCNAGYTCNAGYGCNACNTCNTCNCAYGAYTCNCCNMGN TCNATGGCNGAYTCNCAYATGGARACNGARCCNACNTAY---CCNAAYACNGAYCCNTCN AARTGGAGYGTNATHGAYGTNTAYAAYTTYGTNAAYTCNYTNCCNGGNTGYGCNGARCAY GCNGAYGAYTTYMGNTCNCARGARATHGAYGGNCARGCNYTNYTNYTNYTNAARGARGAY CAYYTNATGACNGCNATGAAYATHAARYTNGGNCCNGCNYTNAARATHTGYGCNAARATH AAYTCNYTNMGNGTNGAYCCNTCNCCNTTYCAYACNACNCCNCARGAYTGYGTNAAYCAY MGNAARGARMGNGCNGTNGTNAARCAYYTNTAYTAYAARGAYTTYGARAARACNYTNAGY CAYGCNCARAGYCCNYTNATHGARYTNCCNGAYTAYACNTAYYTNGAYGGNMGNCCNACN GARATGACNATHGCNTCNAARGARAARGARATHMGNAAYTAYAAYYTNGCNAARCARGTN GTNAARYTNGTNGARGARGTNAARTTYGCNCARAAYGARYTNYTNGCNCARGARCARGCN AARGCNAARTAYAARGARGAYMGNCARAAYTTYCARYTNAARGGNAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNGGNAAYGCNTAYGAYCCNAARGAYYTNGAYAARACNGTN YTNCCNGAYCCNGARYTNTTYGTNMGNTGGYTNCARGTNACNACNYTNATGCCNATHATH CARTTYTCNATHCCNCCNTGGTTYTAYAAYGAYACNATHGTNGARATHTCNAARCARTTY ACNAAYYTNCAYAARTCNTTYGGNGGNAARATHATHGCNYTNGCNGARAAYGCNGTNMGN CAYGGNGARCCNATHATHMGNCCNYTNTGGTGGYTNGCNCCNGAYGAYGAYGAYGCNYTN CARATHGARTCNCARTTYYTNYTNGGNAAYGAYGTNYTNGTNGCNCCNGTNYTNAAYCAR MGNGCNATHAGYMGNGAYATHTAYYTNTAYTTYATHYTNACNATGGCNATHTTYGAYYTN ATHGCNTGYGTNATHGGNATGCCNACNGARATHTAYGAYYTNAAYAAYCCNTAYACNTTY TAYAGYCCNGTNGGNTGYAARATHTTYMGNGGNTGYGARACNTTYACNATHTAYGGNTCN GCNATGGTNYTNGTNGARATHGCNTTYGAYMGNTAYTTYAARATHTGYAARCCNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGTCNYTNGAYYTNGTNTCNAARAGYYTNGARYTNGAR------GAYYTNGAYGARGGN GTNAGYAARAAYTCNAARAARAARAAR---YTNAARACNAAYGAYGCNATGAARATHATH AARACNGAYMGNCARGGNGTNTGGAARGARYTNMGNAARGTNMGNAARCARCARYTNAAR GARYTNGCNAARAARMGNAARACNGARAARTTYAARTCNGCNATHGARATGTAYAARGAY GARTTYGAYGTNGAYCAYACNGAYACNAAYATHGARACNYTNYTNMGNATGTCNAARYTN GGNMGNGTNAARGARAAYCAYGCNCAYAARATHYTNTAYCARCARCCNTGYMGNYTNTCN MGNGAYGTNAARGARACNAARGARGARGCNGARCCNTCNTCNYTNTTYACNGAYGARGAY TTYGARAAYTTYGCNAARGARTAYAAYCCN---------ATGTCNGCNCCNCAYGTNCCN CCNYTNGGNGGNGGNAAYCAR---CAR---------------------GAYMGNCARAAR MGNAARYTNYTNYTNGARCAYATHCARGARCARAARAARMGNYTNCARCAYGGNCAYCAY ---------------------------TCNTCNACNCCNAAYCCNCCNCCNCCNGTNAAY ACNAGYCCNGGNATGYTNCCNGGNATGCCNGCNGCNGARTAYGCNACNATHAGYAAYCCN MGNCARMGNACNGCNYTNCARCAYGCNCAYGCNAAYTCNGTNGGNTAYTTYATHACNCAR GAYTCNTCNTTYGGNAAYYTNATHYTNCCNGTNYTNCCNMGNATHCCNGAYGTNAARACN GAYGCNAARGGNGGNTAYCCNYTNAAYCCNGGNCCNGAYCCNGCNCAYCCNGGNGGNYTN TCNMGNGAYCARTGYGTNACNACNGAYGGNYTNGAYGARGCNYTNTGYTTYGCNTTYMGN ACNGAYAAYACNGGNCCNCCNCARAAYATHGARGARATHYTNTCNAAYTAYGARATHYTN MGNGCNGARTTYCCNAAYGCNGCNATHTTYGCNTCNACNTTYGAYAAYTTYGTNGCNGAR GARTGYGGNACNGTNAARTGYTCNTTYAAYGAYACNMGNATHTTYAAYTCNYTNMGNTTY YTNYTNAARGTNCCNGARCAYACNTGGGGNGCNCAYAAYTTYYTNAAYAGYATHGAYTGG TCNAAYATHGAYYTNATGMGNGCNYTNCARAARGAYGCNTTYCARGARACNCARGTNACN TGGCAYGARCARMGNCARTTYATHTAYYTNGCNATHAARGCNYTNGAYGAYCAYCCNGTN YTNGAYYTNGTNAGYAARGCNATHGCNAARYTNACNGTNACNATGCCNAAYATGAGYGGN TAYTAYCCNGTNAGYYTNACNAGYGARCAYCARTGYAAYGAYGGNAARATHATHAARTTY GCNAARGAYGGNTCNATHTCNMGNYTNTAYGAYCCNTTYAAYAARGTNGARTGGGCNTCN GARTCNAAYMGNYTNGGNCARATGACNTAYGAYACNTAYGTNGARGCNGAYTTYATHAAY ATGTCNGCNCARTAYAAYTAYMGNGCNGGNGTNGGNTTYGAYAARCCNAAYGTNACNGCN AAYGCNCAYCCNGARAARAARCARTGGCCNTTYGGNYTNATHTCNTAYAARAARATGGAR GAYCCN---TGYGAYGTNTGGYTNCARYTNACNACNYTNGAYATHGAYACNCARGTNAAR TAYGGNGCNCCNAARTAYATHTAYATGCAYTAYTCNGGN------CCNGCNGGNYTNGAY YTNACNGTNGARGTNATHAAYAARACNACNACNMGNYTNCCNGARTCNYTNTCNTTYGCN TTYACNCCNAARMGNCCNGAYCAYMGNTGGYTNATGGARAARATGAAYTTYGCNATHGAY CCNTGYAAYGTNGTNYTNAAYGGNAGYCARTAYGTNCAYGCNGTNAGYTCNTCNGTNGGN YTNTAYAAYAARACNAAYCARGGNATGMGNATHGTNGCNCAYGAYTCNCCNYTNATHCAR TGGGGNACNTCNAGYMGNAGYCCNTCNCCNTTYCCNGTNCCNYTNAGYCCNATHCCNTGY AAYAGYATHACNTCNGTNGCNTTYAAYYTNCAYAAYAAYATHTGGAAYACNAAYTAYATG TAYTGGTAYCCNTAYAGYCCNTCNGAYAGYAGYTTYAARTCNMGNTTYAGYATHTAYTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNATHGAYCCNATHGTNCAYGTNACNTGY TCNGAYGGNMGNAARYTNGARGCNGAYCAYGTNATHYTNGCNGTNCCNGTNGGNCAYYTN AARGAYAARGCNMGNTCNATGTTYMGNCCNTCNYTNTCNCARMGNAARYTNGAYGCNATH GAYGARATGGGNTTYGGNTCNGTNGCNAARGTNTTYYTNCAYTTYGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------MGNGARGGNMGNMGNTCNTTYGTNGGNGGNTCNGCNTCNGCN TCNCCNTGYGCNTCNATGTCNTCNTCNTTYCAYGCNGGNTAYAGYAGYGGN---CCNAGY CCNGTNMGNATGMGNGARAARTCNAARCCNMGNAARCCNMGNCCNGCNAGYGTNGGNACN TCNATGCCNAGYTTYGTNGGNGGNGARCCNGCNAARACNTCNMGNAGYMGNAGYACNGAY MGNGTNTCNMGNGAYMGNTCNAARGGNMGNYTNAGYMGNAAR---------AARGAYAAR TCNGCNAARGAYGGNTCNTCNTCNGCNAARGGNAARGARAARAARGARGARGCNGARGAY GARAARGAYGGNGGNACNAGY------AARAARGGNMGNGCNTCNYTNTCNTTYTTYGAY MGNYTNGCNACNCCNAARTTYCARMGN---AAYCARGAY------GAYCAYAARGAYACN CCNMGNAARGARGCNNNNNNNATNMGNYTNTCNCCNMGNAARGCNTAYTCNACNACNAAY YTNTCNACNATGNNNAARNNNNNNTCNTTYMGNGAR---AARACNAARGARAAYACN--- TCNTCNCCNMGNATGGTNGCNMGNMGNGAYACNTCNGCNTCNTCNCCN------MGNACN MGNAGYTCNYTNACNGGNTCNACNGGNTCNCCN---------------------TCNACN AARCCNTCNACNTCNGCNTCNCCNMGNGTNACNCCNCCNCCNCAYAGYTCNGCNAAYCCN TCNTCNAGYCARATGGCNCCNAGYATHACNGTNACNACNGCNCAY---GGNGGNAGYGCN GCNCCNGGNTCNGARGAYGGNACNGCNGCNCCNMGNGCNATGGGNGTNAAYCARGGNATH TCNGARGARGARTAYAARGCNAARATHGCNGARAARMGNMGNCARGCNMGNGARAARGCN GARMGNGARGCNGARGARGARMGNMGNAARCARGARGARGARMGNYTNGCNGARGARGAR MGNCARATGCARGARGARGARGARCARMGNMGNYTNGARGTNGARACNATHMGNYTNGCN GARGARGCNMGNAARGCNGARGARGARMGNYTNCARAARGCNATHGARGCNGARGARAAR MGNAARAARGARGARGCNGARMGNYTNGARCARGARAARAARGCNAARGARGARGCNGAY MGNAARGCNAARGARGARGCNGARMGNATHGARAARGARAARCARGARAARGCNAARAAR GARGARGARGARMGNATGCARMGNAARAARAARYTNGARATGATHATGAARMGNGTNAAR ACNGAYCCNGCNCAR---------GAYAAYAAYAGYGGNAGYAAYAGYTCNYTNAARATG GARTCN---------------------AGYCCNTTYAARTCNTCNGCNGGNAGYTCNCCN AAYTCNCCNGAYGTNCARGARATGCCNGGNGCNCCNCCNGCNACNCARGAYCARGAYCAY TCNTCNGGNTCN------------------------------------------------ ------------------------GARGAYGGNGAYCAYAARCARCARAARGTNGAYAGY GGNGTNACNTCNTCNTCNAGYGAYAGYYTNGAYAAYGAYAARTCNTCNYTNAGYTCNCAR CARGTNYTNACNCCNGTNGTNMGNAGYGCNTCNTCNGGNGAYATHATHGAYTCNACNGAY GAYAAYGARAAYGGNAAYAGYYTNGGNTCNYTNAAYATHAGYGTNAAYAGYAGYACNCCN ACNAAYTCNGCNGAYGGNAGYAAYAAYTCNGARTCNACNACNTCNTCNTCNTCNGARGTN AARTCNMGNTTYAARTCNCCNYTNYTNCARCARYTNGTNGARAAYAARGGNAGYTCNGCN AAYTCNTCNGGNACNCCNAARTTYAARTCNCCNYTNYTNCARAAYYTNYTNGGNAARACN AARGTNGGNGCNMGNATGGGNYTNTCNGCNAGYATGGGNGAYYTNAAYYTNAAYAARGAY ---------------------------AAYAAYAGYGCNACNGCNGAYTCNAGYTCNGGN GCNGAYGCNGCNTCNAGYTCNAGYAARGARATHTCNAARGCNGGNCARGAYGARGAYAAR GAYGTNGAY------GARTCNTCNACNGCNCARYTNCCNCCNAAYACNGCNGTNTCNGAR TCNTCNTCNGCNGARTCNTTYAGYCCNGAYCAYGAYGCNATGACNAAYGGNGTNGAYGAY GAYCAYGARTCNATHATGACNAARYTNCCNGGNAGYAARATGATGGAYTCNGCNYTNGGN GCNAGYATHGAY---------------CCNTCNGCNAAYYTNTTYGTNATGTCN------ ---AAYGGNCAYGGNGGNGAYGGNCARCARCAYGTNATGGARGAYTCNAGYATHGAYYTN CAYTCNCCNGCNGCNACNACNTCNTCNCARTCNGGNCARTCNTCNTCNCARGARGARACN GARGARGARGARGARGARGARGARAARGGNAGYGGNMGNTTYGARGARTAYATHGAYYTN YTNGARGGNAGYACNCAYAGYAARTCNGCNAGYGTN------ACNCCNATHATGGCNTTY GARGAYAAYTCNYTNMGNACNAGYGAYATHGGNGARTCNYTNTCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATHCARTCNCARTCNCCNTGGMGN YTNTCNTTYATHATHGAYGCNATHTGGGGNTTYATHAAYTTYTTYATHYTNTTYTTYCAR ACNATGATHAAYCCNAAYAARAAYAGYMGNGGNGAYAAYTAYACNTCNGAYTAYMGNAAR CCNGGNGGNGGNGGNCCNCCNACNMGNMGNATGGGNGGNTTY---MGNMGNGGNGGNGGN GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTNGTNTCNTCNYTNTAYCCN AARACNATHCAYTCNGARAAYGTNYTNAAYCARATHTAYGARAAYCARAAYAARAAYMGN ACNMGNCCNTGYGTNCARAGYMGNGGNGAYGTNTTYMGNATHYTNAARTAYGAYATHAAY ACNGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNTCNTAYGCNGAYYTNATHACNAARGCNATHCARAGY TCNCCNGARAAYMGNYTNACNYTNTCNCARATHTAYGAYTGGATGGTNCARAAYGTNCCN TTYTTYAARGAYAARGGNGAYAGYACNAGYTCNGCNGGNTGGAARAAYTCNATHMGNCAY AAYYTNTCNYTNCAYAAYMGNTTYATGMGNATHCARAAYGARGGNACNGGNAARAGYTCN TGGTGGGTNATHAAYCCNGAYGCNAARCCNGGNAARACNCCNMGNMGNMGNGCNGGNAGY ATGGARACNAARAGYTAYGARAARAARMGNGGNMGNATHMGNAARAARGTNGARGCNYTN MGNTCNATGGARAAYGGNGGNACNYTNTCNCCNAGYYTNAGYGARGAYTAYYTNGAYGCN TTYGCNGAYTTYMGNCCNMGNGCNAGYTCNAAYGCNAGYAGYTGYGGNMGNYTNTCNCCN ATHCAYGCNGTNGGNGARCCNGAYYTNCAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNACNACNACNACNGARACN AGYCARACNGCNTCNGGNCCNGGNTCNATHCARCCNCARCARGGNTAYYTNAARTCNACN MGNGGNYTNYTNMGNATHGCNGARATHGTNYTNAGYYTNYTNATGYTNATHTGYGCNTCN GTNGAYTAYTGGTCNCAYYTNGGNGGNGGNTGGGTNCARTTYGTNGCNACNGCNGCNATG ATHGGNACNTCNATHYTNTTYGTNYTNTTYTTYYTNAAYYTNGCNCCNMGNATHCCNYTN CCNTGGAAYAGYGTNGARYTNTGGTAYAAYGCNTCNTTYTGYYTNYTNYTNGTNATHGCN TTYATHGTNTGYTGYTTYMGNGCNCAYYTNACNGCNGCNATHGGNGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYGCNTTYYTNYTNCARTGYTCNGAYACNMGNCCNGGNYTNGCNCCNAARACN AARCARAARCARTAYGARCARGARAARAARGARAARGARGCNAAYAARMGNAAYAARATH ATHCCNMGNAARCARYTNGARGTNCARCARMGNCARGARGGNYTNAAYACNAGYATHTCN CARAAYAAYAARGGNTTYGCNYTNYTNCARAARATGGGNTAYAARCCNGGNACNGGNATH GGNAARTCNGGNGARGGNMGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNYTNGCNYTNGAYAAYGGNYTNATHGTNCCNCCN GTNCCNYTNYTNTCNYTNCCNTCNATHMGNTCNTTYAARYTNYTNCCNCCNAARMGNCAY YTNCARCCNCAYGCNYTNCARGGNGCNGARAARGGNGGNTCNTCNGAYGTNTTYATHTAY ACNCCNYTNTCNYTNTCNAGYACNAARACNGAYGAYAGYAAYCCNGAYTTYAARTGGGTN TGYGAYGAYTAYTGYGARGCNGTNYTNCARGTNTTYAAYCCNYTNGTNGAYYTNYTNACN GTNCAYAARATGGCNYTNATGACNTCNGAYYTNGARACNGARGTNATHTCNGCNAGYCCN GCNYTNCARCCN---TCNMGNGTNTCNGARGTNAARYTNTGYGTNMGNCCNMGNGARATH GGNACNYTNAARYTNACNGGNTAYACNACNGARGTNTTYGGNGTNAARAGYATHTGYMGN YTNAARGAYYTNGTNGGNYTNAARCCNTCNMGNYTNTCNGARATHTCNATHCARGTNGTN CCNMGNYTNCCNCARYTNTCNGTNACNTGYTCNYTNCCNGARTCNTCNCCNYTNYTNTCN MGNGGNGGNGGNGCNTAYGTNGTNGCNACNGGNGCNGCNGTNYTNTTYGCNGGNCARAGY GTNGARTGYATH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYATHTGYTCNATHTGYTGYGARTAYGARGARGAR ---TCNACNTTYCCNTGYTGYAARAARATGGTNTGYAARACNTGYTTYYTNAARATHTCN AARTGYCCNTTYTGYCARMGNATHTTYAARACNYTNAARGGNAAYCARCCNYTNGGNAAY ATGAARATHYTNAARAARAGYGTNAAYYTNCAYGGNTTYCCNMGNGGNACNGGNTGYTTY GARATHAAYTAYGCNTTYAARMGNGGNTAYCCNGAY------------------------ ---------------------------GCNTCNTAYYTNAGYMGN--------------- ---------------GTNAARAGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARYTN GARGCNAARGGNGTNACNYTNCARTCNYTNTCNGARTCNGARAARYTNGAYYTNAAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGAYCAYCARTAYGGNATHGCNGTN ACNAAYMGNTTYGCNYTNTTYGGNGAYGARGGNGARGAYCCNTTYGARGCNATHTCN--- ---------------AARAAYAARCCNCARAARGARGCNGARAARAARCCNAARACNAAY AARCCNAARAARGGNAGYGCNGGN---------------ACNGARGAYAARCCNGTNGCN AARAARGAR---------GGNGGNGAYMGNACNTCNAARCARTCNGAYMGNGGNMGNGGN TCNGGNMGNAAYMGNGARCCNMGNGARATHMGNGARAAYGAYGGNGAYAARMGNCCNGTN MGNMGNCARGGN------------------------------------------------ ------CCNMGNGAYAAYAARGAYYTNAARGCNGGNGAYGARAAYGTNCCNCCNGARTTY MGNGARMGNCCN---GARAGYGGNTTYAARMGNMGNGAR---------GAYMGNGARGGN GCNGGNTTYGGNGAYMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNGCNMGNGGN GGNGARMGNGGNGGN------TTY---GGNCCNMGN------------------GGNGAY MGNAARMGNGARTTYGAYMGNCAYAGYGGNACNGGN---GGNGGNATHAARCCNGTNGAR AARAARGARGGNAGYGGNGCNCAYAAYTGGGGNAGYTTYMGNGAYGAYATHGARGARCAR GGNCARGTNAAYACNGCNGAYGARTCNAGYGAYTGGGCNAAYCARCAR------------ GARAARTCNGAYYTNAAYGARAGYGGNGARGTNGARGCNGTNAAYGARGARGARGCNCAR CCNCARCARATGACNYTNGAYGARTGGAARGCNYTNAARACNCARAGYAAR------AAR CCNGCNTTYAAYATHMGNCARGCNGGNGARGGNGTNGAYTCNGCNCARTGGAARGARGGN GTNGARTAYCARAARAARGTNGARGARGARGARGAYGARGAYGAYTAYGARGARGGNGAY CAYATHGAYCAYCAYACNMGNAAY---------AAYAARCARYTNGTNACNGAYATHMGN ATHACNTTYAAYGAYAAYCCNMGNMGNGGNMGNGGNMGN---MGNGGNGGNMGN------ ------------GGNATGGGNGAYMGNGGNGCNMGNGGNGGNGGNGGNMGNGGN------ ------MGNGGNTTYGGNAGYAAR---AARGARTCNGCNCCNMGNTTYGAYGAYGARTCN GAYTTYCCNTCNYTNYTNAARACNGCNGCNMGNTCNYTNTCNGGNGGNMGNAARAARTTY YTNTAYTCNGGNCCNATHTCNAAYAARMGNCAYGARGARGARGAYTGGTCNTTYGTNCCN AARGCNTCNACNCARGARACNGGNCCNAARTCNGCNATHGGNGTNGAYYTNGAYAGYGTN TGGAGYATHMGNAAYGTNTCNYTNGGNAARACNGCNCARTCNGTNMGNTCNGARCCNGTN TCNTTYAARCCNGARGTNYTNACNAARACNACNAAYTCNAAYTTYTAYTCNMGNCAYGGN ------ATGAAYGGNMGNACNGGNAGYCCNAARAAYGGNCARGGNAAYTCNAGYTCNGAY GCNAARAAYTCNTCNYTNTGGTCNAGYTCNGGNCAYAARYTNGGNCCNACNTCNCARMGN ATGAAYCCNCCNATHTTYCARAAYCCNACNGARAARGCNTTYGGNAAYTCNMGNTCNMGN MGNCARAAYCCNTCNCCNTTYGAYTAYGAYATGAAYGAYTTY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNMGNGARGCNGCNMGNACNCAY GGNGTNCCNTAYCCNACNYTNMGNGCNMGNGTNAAYGGNMGNTCNTCNATHMGNCARACN GAYMGNACNGTNYTNAGYMGNGARCARGARAARMGNYTNACNAAYTGGYTNACNGARTCN TCNMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ACNAARAARCARACNAARTTYATGMGNAAYATHMGNTCNACNYTNYTN YTNCCNTTYCCNTTYAAYTGGGGNCCNCCNCCNTCNATHYTNGTNTTYTGYAARGARGAR GARCAYACNAAYTAYGCNYTNTCNYTNGGNGCNMGNCAYGCNGGNTCNCCNGCNGARGTN ATHAARTCNATHGARAAYGGNGTNYTNAAYCCNAARGAYTTYGAYCAYATHYTNGCNACN GCNGAYTGYGGNACNGARATHGCNCCNGCNMGNTCNTAYTTYMGNGAYAARTTYCCNCAR MGNGTNAARGGNAAYYTNGGNACNGAYYTNAAYGARATGTGGAARYTNTTYTAYACNGGN TAYACNTAYGARACNCARAAYYTNACNGAYGCNCARGGNAARYTNCARGTNCCNYTNGGN CARATGAAYCARCCNACNCAYGARYTNGTNGCNAAYTTYGARGCNTAYATHGAYGCNATH TGYAARCAYMGNAGYATHGCNYTNGGNCCNTTYATHCARAGYATGAGYGTNGTNGCNCCN CCNTCNCCNGARGARTTYATHGTNMGNGTNGARGAYTAYGTNCCNGGNTAYAARAAYGAR GARGTNGAYTCNGAYGAYGAYGAR------GTNGAYGARGAYGGNGGNGAYCCNTCNATG CCNGTNCAYCARCCNCCNGARGGNATGYTNTAYCARGTNGARGCNACNCAYMGNTAYACN GGNGARGAYGTNGAYGARYTNAGYTTYGAYGCNGGNGARATHATHAGYGTNATHCCNTTY GARAAYCCNGAYGARCARGAYGAYGGNTGGCARATGGGNATHAARCARTCNGAYGGNATH AARGGNGTNTTYCCNGARAAYTTYACNAARAARATG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARATGATGYTNYTNYTNTAYACNAARGGNYTNMGNGTNATHGTNCAYACNGCNAAY YTNATHTCNAAYGAYTGGCAYCARAARACNCARGGNATGTGGGTNAGYAARATHTTYCCN CCNCAR---AAYAGY---TCNGARCCNGGNGARTCNTGYACNAARTTYAARGCNTCNYTN YTNCARTAYGTNGCNGCNTAYGGNTCNTCNAARYTNGCNGCNYTNGARMGNATHATHAAR GAYCAYGAYATGTCNTCNGCNAAYGTNCAYYTNGTNGCNTCNGTNCCNGGNMGNCAYACN YTNGARCARAARCAYGCNTGGGGNCAYYTNAARGTNAARAARATHYTNTCNAGYGCNGGN CCNGAYCARGGNGTNGTNAARAAYTGGCCNGTNATHGGNCARTTY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARAARTCNGTNGARYTNTTYTAYGAYGTNATHTCNCCNTAYACNTGGTTYGCN TTYGARGTNATGTGYMGNTAYAARACNMGNTGGAAYATHGAYYTNAARYTNMGNCCNTTY TTYYTNGGNGGNGTNATGCARGCNTCNGGNAAYMGNGCNCCNGCNATGGTNCCNAAYAAR GGNTCNCAYYTNATGATHGAYGTNGARMGNGGNGCNAARTAYTTYGARGTNCCNYTNCAY ATHCCNAARAAYCCNGCNGARYTNATGTTYGARAARGGNTCNYTNAARGCNCARMGNTTY YTNACNGCNGTNGAYATGAARTGYCCNGAYAARGTNGARGCNGTNTCNMGNGARTTYTGG ATGMGNGCNTGGAGYMGNGAYGARGAYYTNACNGARGAYGARAGYYTNGCNACNGCNGCN TCNAARGCNGGNYTNAARCARCARGARATHCARGARYTNYTNGCNATHYTNAARGAYCCN GCNGTNAARGARMGNYTNAARAAYGTNACNGAYGARGCNYTNCARYTNGGNGCNTTYGGN TCNCCNATGATHGTNGTNAAYAAYGARGGNAARMGNGARTGGYTNTTYGGNAGYGAYMGN TTYCCNATHYTNGCNCARATHYTNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GCNTGYATHGAY YTNACNGTNGAYATHGGNGGNGAYGARGTNATHGAYYTNACNCARAAYAGYAAYATHATG GARACNCCNGTNGTNATHYTNAGYCCNATGGGNGGNGTNGGNCCNATHMGNMGNMGNMGN GGNAGYGGNMGNMGNGGNATGMGNMGN--------------------------------- ---TCNMGNAGYAAYMGNMGNMGNATHACNATHAGYCCNGARYTNGTNCCNCCNCCNTCN TCNGARACNGAYAGYAGYGAYGARGARYTNCCNGAYATHCCNTTYGAYATHCCNCARCAR AGYAARCARGCNAAYGCNAGYTTYGTNAARTCNCCNTCNYTNTCNATHGCNTGYCCNGTN TGYYTNGAYGAYYTNAARCARYTNAARTCNAAYAARAARAARATHATGTCNACNGTNTGY GGNCAYATHTTYTGYCARGAYTGYATHACNAAYGCNATHAARACNTTYMGNTCNTGYCCN ACNTGYMGNAARTCNYTNACNCARTCNAARATHCAYCCNYTNTTYYTN------------ TCNYTNAARGTNTCNGAYCCNGAYTCNAAYATHAGYYTNTCNCCNMGNGARGAYTAYAAR YTNAARMGNCARAAYMGNAGYAARACNYTNCCNATGGGNCCNGCNGTNGARGARAAYAAY TCNCCNAARGTNCARMGNGCNAGYTCNCAYMGNTTY---CCNGCNGARCCNTCNTCNTCN CARCARAARAGYACNAAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------MGNCCNTTYAARTGYCCNTGYGGNMGNACNTTYGCNMGNAAYGARGARYTN ACNMGNCAYCARMGNATHCAYTCNGGNTAYAARCCNCAYMGNTGYCARATHTGYYTNAAR ACNTTYGGNMGNAARGAYCAYYTNAAYAARCAYGTNAARACNCAYYTNCAYTCNTCNCAR AARAARGTNCAYGTNTGYAAYATHCCNGAYTGYGGNCARAGYTAYACNMGNACNGAYGCN YTNGCNMGNCAYCARATGAAYGCNCAYGGNATHAARGCNAARCCNTCNAARTGGMGNCCN CAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNAGYAAYYTNCCN---AAYAGYAARGGNCCNGCNMGN ACNATGYTNAAYYTNCCNAAYYTNATGCARAARGARYTNYTN---CAYGARATHAAYGAR TTYTAYYTNTTYCAYTCNACNAAYMGNAARGCNGCNYTNAARATHTGYCARGARGGNTTY GAYCCNMGNYTNTCNAGYGGNAARGCNATGTTYGGNAAYGGNGTNTAYTTYGCNGARAGY TCNACNAARGCNGAYCARTAYGCNGAYAAYCCNGAYAAYMGNCARCARAAYGGNACNGAR YTNACNATGTTYTTYAGYMGNGTNGTNYTNGGNCAYGTNTTYYTNTGYGAYGAYAARCAY GARAGYGTNMGNAGYAAR---------------GARTGYAARAARYTNTCNMGNCCNCCN TGYYTNTAYTGYMGNGARGCNCARMGNCAYCAYTCNGTNYTNGGNGGNATH------TGG TTYGTNGTNTAYGARGARGAYATHACNTAYTGYMGNGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ACNCARGTNATHAARAAYGTNAAR GARTTYYTNACNAAYATHMGNATGGCNMGNGGNGTNAARAARGCNAGYTAYGARCAYATH GAYCARTTYYTNYTNTCNYTNGAYYTNYTNMGNAARATHTTYCARGAYATHGARAAYGAR ATHGTNCAYCCNYTNYTNCARGTNCARGGNATHTTYGARAAYGARAAYCARAARAGYYTN AARCARACNATHAARAARACNACNACNGARATGYTNGARAAYYTNAARCARGAYGCNGAY YTNATGAARATHMGNCAYAARGARTGGGARTCNAARGTNYTNACNMGNGARCARGGNYTN TTYTAYGGNYTNATHAGYYTNATHCCNATGGCNATHGAYMGNYTNACNACNATHGAYTAY AGYGCNGAYGARTAYATHAAYCARATHCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYAARATGGTNGARGCNCAYGGNACNTTYTCN ACNYTNGGNGGNAARATGAARYTNAAYATHCCNAARCARYTNGGNTGYAARYTNAGYGTN GARAGYYTNTCNYTNATHAARTCNAAYGAYAARATHGAYAARAARGGNMGNGTNTGGGAR GAYGGNGARGTNCARTCNTCNCAYAGYGARGAYTCNACNAARGAYGAYAGYGAYTCNGAY GAYGAYGGN------YTNTCNGARACNGGNTCNATHAAYTCNGAYAARGAYTGGAARTCN CARAGYTCNTCNAARCAYAARAARAARMGNAARCAYAARCAYAARAARAARAARAARAAR AARTCNAGYAARGARAARGAYAARACNCARGAYGARAARGAYGGNMGNAARAAYMGNGAY MGN---AAYAARGGNAGYMGNGTNGARAARGAYGARTCNACNAARGCNGAYMGNGARTGY TCNTCNAGYYTNAARGAYAARTAYAAYACNGAYAGYAGYATHAGYAGYAARACNAARGAR AAR------------------------GGNAGYGAYAAYGARAGYTCNAGYACNAARGAR GAY--------------------------------------------------------- AARGGNGAYAARGARATHAARMGNMGNGAYMGNGARMGNAARMGNMGNCAYAAYMGNTCN MGNTCNGGNAGYCCNAARAARTCNAARMGNTCNMGNTCNMGNTCNAARAGYCCNMGNAAR TCNMGNMGNAGYTCNAGYCCNAARMGNAAYMGNTAYGAYGARTGGGAYGCNMGNMGNTAY AGYGAYAAYTCNAARMGNGGNMGNTCNAARGARMGNGAYMGNTCNAARGARGCNAARMGN GARAARAARGAYGGNGARAARGAYYTNMGNYTNCARATHGAYAARGCNAARYTNMGNAAR ATHGCNATHGCNAAYACNYTNAAYACNATGAARATGGGNCARCCNGTNCCNGCNCAYGTN GAYGTNGCNGCNGTNAARTCNGGNGGNAARTCNGTNGARGARYTNACNGAYTTYTGYAAR MGNATHTCNGARAARGAYCAYGARMGNCARGARAAYGCNGTNAGYGAYAGYAGYGARGAR GAR---GCNCARAGYGAYGARGARGAYACNYTNATHCAYCAYCCNTTYAARGTNAARGAR GCNACNACNAAYATHGTNATGAAYATHMGNAAYGCNAARCARYTNCCNGTNYTNACNCCN TCNGARAARCARGCNCARCARGCNCAYYTNMGNYTNTCNTTYCCNGTNTCNAGYGGNAGY CAYCAYMGNGCNAAYGARTCNGARTGGGTNCCNGTNGARAARCCNACNGCNCCNGCNACN TCNGCNATHAGYAAYGGNACNTGYTCNCARCCNGCNTCNGTNACNAGYCCN------GAR CCNCCNAAR---------AGYATHTTYCCNTCNTCNCARCARAAYGTNGAYATHAGYACN ATHATHTCNGARMGNYTNCARGCNGTNMGNAARYTNCARCARAAYCCNTAYGAYGTNCAR GCNYTNAGYTCNATGCAYAARGCNCARGARAARGCNAGYCARTGGGCNCARTCNAARTTY YTNCCNGGNCARTTYACNGGNAGYACNGGNGCNCARGTNATGTCNCARCARGARATHATH GGNGAYAARMGNCAYCARGCNTGGGTNAARAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYACNTCNYTNMGNATHTTY ACNTGYCCNATHMGNGAYGTNCARTCNTGGAGYGARGCNGGNTTYTAYCCNGGNACNATH YTNTTYGARATHTAYGGNYTNATHATHTCNGGNCCNACNGAYACNAAYAAYGGNGTNGGN AARGARTTYTAYYTNMGNGAYCARTCNGCNACNATHMGNTGYGTNTTYTAYGARATHGAY MGNGARATHCCNTCNATHATGAARGGNCARGTNCAYMGNGTNGTNGGNTGYATHGTNATG AARCARAGYTAYYTNAARGTNGTNTCNYTNMGNAARGCNGAYAARATGGARMGNGTNGCN TGYCARAARGGNACNGARYTNTCNYTNAAYGARATGGAYAARYTNGCN---CCNGGNYTN CAYCAYTCNAAYTTYACNMGNGAYGAYAAYCCNAAYATHCARTCNYTNATGAGYGAYGCN GAYGAYCCNTTYATGGGNGAYAARTCNAARTCNYTNTTYGGNTAYGAYTGGGARAAYMGN ACNTTYTCNYTNTCNTTYCARATGAARGCNTCNAARYTNATGTAYAAYCAYAGYATHCCN AARCARGAYYTNYTNTAYAARATGGAYGTNACNTAYGTNGGNAARACNTCNTTYCARATH MGNGGNCARTTYTTYYTNAARGCNATHGARGARCCNGTNYTNAGYTAYYTNCAYCAYATH GTNAAYATHGAYGAYMGNACNMGNTCNTCNAARCCNYTNCCNGCNTGGATHTCNCARMGN GTNAARAAYYTNCARACNCCNGARAAR---------GTNGARAARATHAGYMGNCCNCAR GARACNTTYGTNTAYMGNGTNTGYGTNACNTGGTCNGAYACNGAYACNAAYTCNCAYTGY AAYTTYGCNAGYTAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CARGCNGARGARYTNGGNTGY GARGGNAARGTNGARGARTCNCARGGNGTNATGAARYTNGTNGAYCARYTNAARGARGAR MGNGARCARYTNGAR------AAR---CARCARGARGAYGGN---GGNCCNATGATGAAR CARATGGARGTNTGYGARGTNTGYGGNGCNTTYYTNATHGTNGGNGAYGCNCCNCARMGN CARGAYGARCAYYTNATGGGNAARCARCAYGCNGGNTAYGCNCARGTNMGNAAYGARATH GARMGNMGNAARCARAARGCNMGNGARGARATHGARGCNMGNGARGCNAAYGARAAYAAR ATGMGNATGGARMGNGARGGNMGNGARAARGAYMGNCARAARGARMGNGARGAYAARMGN CAYAARGARAARGAYAAYGAYMGNGAYMGNGAYMGNGAYMGNGAYAARMGNMGNMGNAGY MGNTCNMGNAGYMGNAAYMGNGGNAARGAYMGNMGNMGNTCNMGNAGYMGNGARMGNMGN MGNMGNMGNAGYTCNAGYMGNGAYMGNMGNAGYMGNMGNAGYACNAGYMGNAAYMGNGAR MGNGAYMGNMGN---MGNAGYTCNAGYMGNGGNAARMGNTCNMGNMGNTCNTCNAGYMGN GARMGNMGNMGNGAYAGYMGNMGNAGYMGNGARMGNAGYTCNMGNAGYAARGCNMGNTCN GAYTCNAARGAYAARATHGARAARGAYAARGARAAYGGNGARAAYAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGAYTTYGAR TCNTCNACNAARTTYATHTCNTCNYTNGGNAARTTYYTNCARTCNYTNTGYAAYGGNTAY GTNGARTTYGAYAARGGNGTNGARGTNATHGGNCAYATHTAYYTNAGYGTNGAYAGYGAY ACNTGYAARAARATHGAYTAYGTNYTNAAYGARAARGTNTGYAARAAYGAYAAYTCNGTN ACNTTYATHAGYAAYAGYTTYCAYGCNCARCCNGCNGARAARCCNAARCCNCCNCCNAAR CCNYTNGARACNGARAAYACNAAYGARGGNTCNYTN------GAYGARCCNGGNCARTCN TTYCCNAAYAGYACNAAYGTNGGNACNACNGGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNCARACNTTYGTNCCNTGGAAYGCN CAYGARACNGCNCCNGGNACNTTYAARTGGGAYGGNTTYTCNGAYYTNGARAARTTYYTN AAYYTNGCNAAYCARGARAAYYTNGTNGTNYTNYTNMGNYTNGGNCCNTAYATHTGYGGN GARTGGGARTTYGGNGGNTTYCCNGCNTGGYTNYTNACNGARAAYCCNAAYATGATHYTN MGNACNAGYGAYCCNGCNTAYATGAARTGGGTNACNYTNTGGTTYCARGARYTNYTNCCN AARGTNAARMGNTTYYTNTAYAARAAYGGNGGNCCNGTNGTNATGGTNCARATHGARAAY GARTAYGGNAGYTAYTTYGCNTGYGAYMGNAAYTAYATGYTNAAYYTNMGNGAYATGGTN ACNGAYGCNYTNGGNAGYGAYGTNATHATHTAYACNACNGAYGGNAGYGGNGAYGGNTTY YTNAARTGYGGNAARACNCCNGGNCCNYTNGTNAAYTCNGARTTYTAYACNGGNTGGYTN GAYCAYTGGGGNGAYCCNCAYTCNAARACNAAYGCNATHAARGTNAGYAARAGYYTNGAY ATHYTNYTNGGNTAYAAYMGNTCNAAYATHAAYATGTAYATGTTYGTNGGNGGNACNAAY TTYGGNTTYTGGAAYGGNGCNAAYGARCCNCCNTAYCARCCNGTNCCNACNTCNTAYGAY TAYGAYGCNCCNATHTCNGARGCNGGNGAYATHAGYACNAARTTYTTYGCNATHMGNGAY ATHATHTCNAARTAYYTNCCNYTNCCNGARTCNGAYATHCCNTCNAAYACNACNAARATG AAYTAYGGNCCNGTNGARATGAARTTYMGNTGYACNATHCARGAYTCNYTNGARGTNYTN TGYCCNAAYGGNCCNGCNTCNTCNAARTAYCCNATHCCNATGGARAARATHAARTTYTAY CAYGGNTTYATHYTNTAYMGNCAYATHYTNACNAGYAAYGTNACNGARATGACNGARYTN CAYACNTGGGGNATHMGNGAYMGNGCNATGGTNATGATHGAYGGNATGCCNCARGGNATH YTNGAYMGNACNYTNCARYTNTCNGTNAAYGTNACNGGNCAYAARGGNCARTAYYTNGAY ATHYTNGTNGARAAYCARGGNMGNGTNGGNTTYTCNACNGAYATGAAYTTYAAYTCNAAR GGNYTNATHGCNAAYGTNTCNYTNGGNGGNAARGTNYTNACNGAYTGGYTNYTNTAYCCN YTNGAYTTYAARAAYYTNAAYAAY------YTNAARGCNATGGGNMGNTCNGGNAAYYTN MGNTCNCCNCARMGNTCNMGNGAYGGNMGNYTNATGACNCCNTCNTTYTAYATHGGN--- ---YTNYTNACNTCNAARAAYGARYTNCARGAYACNTTYYTNGAYCCNYTNYTNTTYACN AARGGNCARGTNTTYYTNAAYGAYTTYAAYYTNGGNMGNTAYTGGCCNAARMGNGGNCCN CARGTNMGNYTNTTYACNCCNAARCCNGTNTTYYTNCCNAARACNACNACNAAYACNTTY TTYGTNTTYGARGTNGARAAYGCNCCNTGYAAYTTYACNTCNGGNTGYAGYATHTCNYTN GTNAAYAARCCNTAYYTNGAYGGNCCNGTNAARTCNATHATGGCNGCNGTNGARYTNGAY CCNATHTTYGTNAARGCNYTNAARYTNYTNCARTCNAAYACNAARGAYAGYGGNGCNCAR YTNAARGCNATGYTNGAYGAYGTNATHGCNCARMGNAARGGNYTNAARACNATHTCNCAY TCNGGNGAYTTYGAYAARGTNTCNYTNTCNAARGGNAARACNGAYTCNGARYTNMGNMGN AARGAYGCNGARAARMGNTCNYTNGARAARGGNACNAARGAYTCNTCNGARCCNGAYGTN AARAARTCNAARYTNGARCARTCNTCNAARCARAARGARAARGARAARGARAGYMGNGAY AARGARMGNGARMGNCAR------AARMGNGARAARGARAARAARGAR------------ GARGCNCARMGNGARMGNGAYMGNGTNGARAARGARAARAARGARMGNGARGARGTNTCN ---------AARYTNGGNGCNGARGTNATHAGYGAYGARGARGARCCNGCNCARTCNATG GAYGCNGGNGAYTTYGCNMGNGAYYTNGGNATHAAYTGYGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AGYYTNCCNAARATHACNMGNAAYCCNACNGAYCAYMGNGTNTAYGAR GGNGGNAARGTNAGYTTYTTYTGYCARGCNTCNGGNAAYCCNACNCCNACNTTYAAYTGG GARAARAAYGGNAARMGNATHMGNGARGARGAYGARMGNTAYAARGTNCAYGAYGTNGCN CAYATGTCNGCNYTNCAYATHGARAARGTNYTNYTNAARGARGAYAAYGCNACNTAYTCN TGYYTNGCNACNAAYGAYYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNCCNAGYTAYATHATHGTNGARGAYATH YTNTCNTAYGCNTGYCARAARCARGAYAARCCNGTNGARAARACNYTNGCNYTNYTNYTN TCNYTNATHTCNGAYGCNMGNMGNTGGATHGCNAGYCAYAAYGARGCNGGNAARTGYTAY GTNGTNYTNACNGCNCCNTCNMGNATHAARTCNATGCARAAYATHYTNTGYMGNTTYAAY TAYCAYYTNGCNGTNTAYGARGGNCCN--------------------------------- ------------------------------------------------------------ ------------------------------------------YTNATHCARATHAARACN GCNGAYGARAARGARGTNTTYMGNMGNATHGARTCNTTYATHMGNAAYAARMGNAAYGAR GTNAAYGARMGNAAYATHMGNGARTTYATHTCNCCNTCNGAYTCNGAYGAYGGNAGYAGY TGYGCNMGNGTNGARGCNGTNTAYGTNCAYMGNGARGGNATGAARAGYCAYATHAAYYTN AARACNGTNGARAAYACNCAYGGNCCNCARACNMGNYTNMGNCCNCAYTTYAAYGAYGAR ATHCARGCNTGGGARATGCCNGCNGAYATHCARMGNGCNGARGCNYTNGARGARMGNATH GTNAAYATGGARACNCAYYTNAAYGTNTCNAAYGGNTCNAGYAGYYTNCAYCARMGNATH AARTCNYTNGARGARMGNATHAGYTTYYTNGARGGNATHTCNCCNGARTAYTTYACNAAY GGNATHCCN---------------------------------------CARATHCCNATH GTNCCNACNAARCARACNTCNGTNGARATHTCNGAYCAYATGACNGAYATHATHGTNAAY AARTTYGARGAYMGNYTNTTYATHATHGTNACNCARTAYCARAARATHGGNACNYTNATH GARGTNTCNMGNGAYGTNATHTCNGAYGARGTNCARGGNYTNATHCCNATGTTYTCNACN AAYGTNGTNYTNGGNAARGAYGARCCNYTNACNCAYGTNATGGCNAARACNATHGTNACN GCNYTNAAYCCNCCNGTNCCNGTNYTNYTNGGNYTNGCNYTNAARGTNACNACNCAYGAR GTNGTNCARGCNGTNATHGARAARATHAARTCNTGYYTNATGGCNACNAAYATGCAYTTY GARGCNMGNMGNMGNCARATGGTNATHGAYAARGCNCARMGNGCNAARGARAARATGAGY YTNACNCAYCARAARGAR---AAYGTNTCNYTNTCNGCNGARACNTCNAAYAARCCNGAR ACNATHGTNTGYACNGAYCARGGNCARTTYTAYCARACNMGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TTYTTYATGGTNACNACNTCNTCNAAYACNGAYYTNGGNTCNGCNYTNMGNCAY ATHYTNGGNGAYGAYYTNTCNCCNTAYATHATHACNAGYCCNGCNGGNTGGGTNACNTGG GAYACNAARGCNTTYYTNYTNAARGGNACNCARATHGAYATHYTNMGNMGNATGCCNAAR TTYTAYGARGAYGTNGAYGARAARAGYATHAARCCNMGNYTNGCNTGYGARGGNATHMGN GAYGAYYTNYTNGARTGYYTNYTNAARAGYGAYTGYTGYAARAARGARAARAARACNCCN MGNGARTGYATG---------AGYMGNATHGGNGAYCCNTCNGTNCCNGAYGARTGYTCN AARYTNMGNGTNGCNTTYTTYGARTGYMGNMGNTCNGTNYTNGAYATGMGNACNMGNTTY MGNGGNMGNAARGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------YTNTCNAAYAGYGAR AGYGCNGTNATHGGNATHYTNGTNGTNATGTGYATHGTNGGNGCNGGNATHGGNATGTTY GTNTGYTAYMGNMGNAAYAAYATGACNCCNMGNAGYATHAARGCNYTNTTYTCNGGNGGN GTNMGNTAYAARTCNTAYACNAAY---TCNTCNTTYACNACNGARGARGTNGTNATGGGN ---GARAARTCNAAYAARAAYGCNATHCARGCNAARATHAAYMGNGARAARAARAARGCN TAYATHAARAGYYTNGARGAYGARATHAARTCNYTNMGNGCNGAYAAYGARAAYTTYAAR ACNGARAAYTCNAGYATGAARACNMGNGTNTGYGGNYTNGARGARGARGTNCARTAYYTN AARTCNGTNYTNATHAAYTCNAGYTCNYTNTCNAGYYTNYTNAARAAYATHTCNAAYGTN AARGARGTNAARYTNTCNGCNACNGTNATGGGNMGNAARMGNTCNATHGARGAYGAYCAY AAYTAYAAYTTYAAYYTNACNGARAAYGCNAAYCARAARMGNGCNMGNYTNGTNAAYGAR AAYYTNMGNAARGCNGGNGTNTGYYTNCAYGTNGAYGGNAAYTCNGCNAGYYTNGARTTY TGYGTNAAYTGYTCNAARYTNGCNMGNAARTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------AARGARCAYTGG TGGAARCCNCAYATHAARMGNYTNACNGAYATHACNAARMGNGTNAARGARATGGGNGAR YTNTTYTGYCARCAYTAYATHAARTCNACNAARAAYGAYCCNGARGCNCAYATHGAYTTY GCNMGNMGNMGNYTNCARYTNGGNGARAGYYTNTAYTAYAARACNYTNGARGARATHYTN AGYGGNGARAARMGNMGNYTNGARMGNAARGCNATHGAYYTNYTNGCNYTNYTNGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ACNGCNATHGARGCNGTNACNGCNGCNGTNAARACNYTNGAR GAYGAYGARAARACNAAYGCNGGNTTYGGNTCNAGYATGACNGARAAYGGNGAYGTNGAR TGYGARGCNAGYYTNATGGAYGGNAARACNYTNMGNTTYGGNGCNGTNGCNGCNYTNTCN GGNGTNCARAAYGCNATHAARGTNGCNACNYTNYTNGTNACNGARCARGCNAARGGNCCN YTNCCNTAYGGNMGNATHMGNCCNAGYATHYTNGTNGGNAARGGNGCNAARACNTTYTGY CARGARCAYGGNATHGAYATHAAYTAYAAYCAYATHTCNAARGCNGCNYTNAARACNTAY ACNMGNTAYAARMGNAARTGY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGGAY ATGGARGARYTNAARTCNGTNTAYTAYGGNYTNGAYATHYTNAGYGARCCNGTNYTNYTN GARAARCARYTNCCNYTNGGNGCNGTNCAYGTNACNTCNAARTAYGGNCARCARTAYCAR TGYAGYTTYCCNGAYCAYTCNGARGCNGARAARAARAARGARGARGARGARAARGARGCN GTNGARATGGGNATHGTNGARATGYTNAARCCNYTNCARTCNAARCCNTGYYTNACNAAR ACNAARGAYTGGTGGACNTAYGARTTYTGYTAYGGNAARCAYATHMGNCARTAYCAYATG GARGAYAARAGYATHAARGGNYTNATHATHCAYYTNGGNTTYTAYGARAGYGAYTTYGAY TGGAAYAAYGAYACNGCNAARGAYGARMGNYTNAARGCN---AGYTCNYTNTCNAGYTAY CAYTCNCARACNTAYTCNYTNGGNGAYAARTGYGAYYTNACNGGNAAYCCNMGNCARGCN GARGTNMGNTTYGTNTGYGARGARAARGCNCARGAYCARYTNTCNMGNATHGARGARTCN GARACNTGYGTNTAYACNYTNACNGTNGTNACNTCNMGNACNTGYMGNCAYCCNTAYYTN AARCCNCCNYTNCARMGNAARGCNGTNGARATHGAYAAYGTNAARAARMGNTTYAARMGN ACNGGNGARAARYTNMGNTCNATHAARACNAARYTNGCNAAYGARAARYTNTGGGARAAR AAYATHGARGAYGCNGTNAARGARGCNGARGARGARYTNGGNGTNAARGTNAAYCAYAAY YTNGTNTCNGGNYTNTCNAARACNYTNAAYAARYTNGTNAAYAARYTNCARGAYACNGAR GCNGARTGGTCNTCNATGGARAARGARATHGARGGNYTNGAYAARACNGTNCAYGTNATH CARCARGARGAYAARGAYGGNAAYACNAAYAARTTYATHTTYGTNYTNGGNTTYAARAAY ATHGAYGARGARGCNACNGARCARGARMGNCARTCNACNYTNGARGARAAYTAYGARTTY GTNTAY---------CCNATHGCNMGNATHATHATHACNGGNGCNACNGGNATHATHTTY GGNATHGCNYTNGARAARGGNMGNGTNTTYGARCCNCARGTNATHMGNGAYCARATGYTN YTNMGNMGNTTYGGNATGYTNAARATGTTYYTNTCNGCNTCNGCNGTNGGNATGATHTGY TTYTCNATHYTNAGYYTNYTNCCNCARACNGTNMGNAARTTYGGNATGGCNYTNAARAAY TAYCCNGAYMGNTCNAGYTAYAARACNGTNTTYGGNGTNGTNACNGGNGCNTCNYTNYTN GGNTGYGGNATGACNATHGCNGGNGCNTGYCCNGGNACNATHYTNGTNCARGTNGGNTCN GGNGTNCCNAAYGCNTGGGTNACNGTNYTNGGNGGNYTNTGYGGNGCNTTYYTNTAYGCN YTNACNAAYTCNGGNYTNCCNTCNTCNATGYTNGARAARGCNAARCCNAARTAYTTYTAY YTNAAYAAYTAYYTNMGNACNTCNTAYATGCARATHGCNGTNCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATGCARGAYGARYTNTCNMGNGTNATHTCNGARYTN GARGGNGTNAARACNGCNGCNGCNGTNTCNGARAGYAAYAARCARCARGARATHAGYAGY GCNATHACNAAYTAYCARCARGARGTNGCNACNYTNCARGARYTNYTNAARGARGCNGCN GAYACNGCNTCNGAYAAYACNGCNGCNMGNTAYGARTCNGARMGNAARAARYTNGTNACN YTNAAYGARAAYTAYGARGARGARATHCARGAYYTNMGNAAYAARYTNACNCARGARMGN GARAGYTTYYTNTCNTCNGTNGCNAARTCNATHAARTGGGTNGGNAAYGTNGGNAGYGGN AGYACNGARATGTAYGTNGCNGTNYTNAGYACNCARAARGGNGTNYTNCARGAYGAYGCN GAYAARGTNMGNGCNGARYTNTCNGARGTNTGYCARYTNYTNGARGARGARMGNCAYAAY CAYGARTCNYTNAARCARACNTGGCARATGGCNAAYGAYCARTTYYTNGARTCNCARMGN YTNYTNATGATGGAYYTNMGNMGNATGGARGGNGTNYTNTCNTCNGARCARCARMGNCAR ATHTCNGARYTNCARCARAARGAYGARCARMGNGARGCNCARAARAARAARGTNGCNGAY YTNGARGARAARMGNGARAARCAYGARGARMGNMGNAARYTNAGYCARTCNMGNATGGGN CARMGNAGYMGNAAYTCNTCNCCNGCNCAYTCNATHACNGAYATHCCNGAYGGNYTNMGN GCNGCNAGYGGNTCNATHACNTCNCARGGNAGYATHGGNGCNGTNGARGAYGARGARGAY GCNATHTTYYTNGAYAGYGGNTCNTAYGAYMGNMGNTCNYTNGGNGAYAGYGARGGNTGY GAYYTNAARGTNAGYCCNGARMGNATHCCNGCNYTNACNGTNGCNCARATGAARGCNATH ACNGAYCCNACNCCNGARACNGARGCNCAYAARTCNATGYTNGCNAGYYTNMGNTCNAAR GGNGGNTCNYTNAAYYTNYTNAAYTAYCARTCNGARYTNGARGARGCNYTNAARAAYGCN GCNGARGAYGCNCARTCNCARATHACNCARYTNTCNAAYAARGTNATGGARCAYGARAAR TAYGCNCARGARYTNAARGARCARATGACNTCNACNCAYYTNCARYTNGARGARCARTGY AARTCNYTNTCNGAYAAYMGNGARACNGTNCARGCNGARYTNGCNAARYTNGARGARGAR AAYGAYAGYYTNATGGAYAARTAYTCNAARACNGCNCARCARYTNCARAAYGARGAYATH AAYYTNCCNAAYAAYYTNGARGARATGCARYTNYTNYTNYTNAARTAYMGNGARGARATH ATHACNGCNAARGTNGCNAARGARCAYACNGAYGARACNYTNMGNAGYCARATHGCNTTY YTNAARTCNCARGTNYTNGGNGARCARCARGARAARACNACNYTNGARGARACNYTNTCN CARGARATHACNACNYTNCARTCNAARYTNTCNGAYTTYGAYACNATHAARCARGARYTN GARAARGARTCNTCNCARMGNGTNGARATHGARTCNAARYTNAARGARTCNGARYTNGCN GTNAARGGNACNCARGCNAARTCNAARCARATHATHAGYAARYTNCARGARAARYTNGAR GARGARGAYAARAARMGNACNAARYTNGARTCNGAYCAYCARCARYTNMGNAAYAARGTN CARTCNATGCARGTNGAYYTNGAYAAYAGYGARGCNGTNCARMGNGAYTTYGTNAARYTN TCNCARTCNYTNCARATHCARYTNGARAARATHMGNCARGCNGARACNGARGTNMGNTGG CARCAYGARGAYGAYATHGAYGAYTGYAGYAAYTGYAARCARTCNTTYTCNGTNACNAAR MGNAARCAYCAYTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CARCAYATHTAYACNMGNATG GGNYTNTGYYTNAARTCNATHYTNTCNGCNACNMGNGCNGTNCCNGGNTAYMGNYTNGCN AARAAYCARGGNGARAARGGNGGNGGNTAYGTNYTNAAYTGYMGNATHTAYYTNGGNCCN CCNAARACNCAYATGYTNGGNGAYGGNTTYAARACNGTNMGNGCNGGNGCNGTNCCNTCN GCNTAYGGNYTNYTNGGNGTNAAYGTNGCNTAYMGNACNAARYTNYTNYTNTCNCCNGAY ACNACNTCNTGYACNGAYAGYATHATGCARGTNACNGAYGAYTAYTTYATGCARGARCAY ATGGCNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARATHGARYTNYTNTGGGARGAY AARGCNTCNAAYCARYTNYTNGCNAGYGTNMGNYTNTAYTTYMGNCCNGARCAYACNCCN GAYGGNMGNCARGAYGAYTCNGGNGARGAYGARATHGTNGTNYTNGGNGARMGNYTNGTN GTNMGNYTNGAYGAYYTNYTNCCNYTNYTNGTNGARGAYTTYAARTGGACNTAYGGNAAR GCNCCNTTYGCNGGNAARGCNCCNGGNTGYMGNGTNATGTTYTGYMGNGARACNTTYTAY CARTCNGARATHGAYGAYYTNGAYATHMGNATGGAYCAYATGATGCCNACNYTNAARAAY MGNCCNMGNGGNAARAARAARAARGARYTNTCNMGNAARGAYTCNCARCARGAYTCNGAY AGYACNGARGARYTNTTYGCNAAYGTNACNCCNACNGTNTCNACNTCNTCNMGNCCNMGN MGNTCNAAYGAR------------------------------------------------ ---------------------------------------------------------GAR AARCARAAYAARTTYCARGGNYTNGARYTNYTNAARMGNATHCARGARYTNATHCCNYTN GCNAARTCNGTNTCNGCNGTNAARCAYAGYATHACNGCNTTYACNMGNMGNYTNYTNAGY YTNYTNGAYGARMGNAAYGTNYTNGAYAAYCARGARYTNTCNCARGARATHYTNAARTGY YTNAARACNTTYTGGTCNATHTGYTCNAGYAARCARTCNGCNYTNTCNTCNCCNAARYTN YTNGGNMGNTGGGAYGCNACNYTNATHGARGARGCNACNGCNYTNGCNTCNATHTTYATH GAYYTNTTYATHGCNGCNAAYGGNACNAARGARAAYCARGCNGTN------TGGTCNAAR MGNYTNTTYAGYTGGYTNAAYTTYGAYYTNCCNGAYMGNGCNATHAARGTNGCNYTNYTN GARGTNACNGGNCARAAYMGNAARGARGCNGARATHGCNGGNCCNYTNGTNAGYCAYGTN YTNCARMGNAARTTYGAYTAYGAYTCNTGYCCNGAYTAYYTNYTNCARTTYYTNGTNTTY AARAARTGGCARCAYYTNACN---GAYGTNGCNCCNATGGARAARACNTGYAARTCNYTN ATHGCNCCNTCNCARTTYYTNTCNTGGYTNAARACNTTYTGGGARCCNGTNGCNGAYTAY GTNCCNACNGAYAARAGYYTNAARGGNTCNATGATHAGYCARTTYYTNYTNGAYYTNGAY ACNTCNGAYGTNTTYGAYTCNYTN------------------------ACNGAYGCNYTN AAYGCNGAYAAYGTNGARAAYGGNGCNGCNCARCCNGTNTTYGTNGTNGAYAARCARGGN ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNGTNAAYTCNACNGGNAGYCCNATHGARCARMGNMGNCARGTN---GTN ATHAAYATHCCNCCNGGNTCNYTNTCNGGNGGNTCNGTNACNCCNGCNGGNGCNAAYACN AAYTCNCAYCAYATHMGNATGCAYTTYGGNGAYACNGGNGGNACNTGYACNGTNAARMGN AAY---------GGNGTNAARGTNMGNAARMGNGAYTGYATHGGNCCNTTYTAYAARGGN AARCCNTGYCCNGGNGARAARGARGARGARGTNAARTGYAARAARACNCCNTGYCCNATH YTNCCNCAYAAYTTYCCNATHCAYGARTGYACNGTNAARAAYTTYACNTGYACNAGYCAR AARATGTGYATHCCNYTNMGNCARAARTGYGAYAAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNCAYCCNAAYGGNCAR GARAAYGGNAGYTGGGCNATGTTYGARGAYGARGARAGYCAYATGYTNATHGGNTCNGGN GTNAARCARCAYTAYAAYAAYYTNGARYTNCCNAAYTTYGAYTCNTCNTCNATHTCNTCN GARGCNGARAGYGTNGAYGAYGTNTGGTGYATHAAYGAYGARCARMGNGARTAYTAYATH ATGCARCCNGAYYTNAAYAAYGTNATHACNGGNCCNGTNGCNAARCAYTTYTTYGARAAR TCNAARYTNCCNGTNACNGARYTNTCNACNATHTGGCARYTNTCNGAYYTNAAYTGYGAY GGN--------------------------------------------------------- ------------------------------GARGAYGGNAARTCNGTNATHGARAARGAY GARMGNGGNATGCCNGTNTAYAARGTNMGNTTYAAYATGAARGAYTAYMGNCCNGARGAR GTNAAYGTNAARATGGAYAAYAAYAARATHATGGTNTCNGCNMGNCAYGARGARAARGCN AGYGGNTCNACNGTNAGYMGNGARTAYAAYMGNGARGTNAAYGTNCCNAAYGARGTNGAY CCNYTNGCNYTNCARTGYYTNTTYCARCCNGAYGGNTAYYTNGTNTTYAGYGCNCCNATG CCNGTNCCNAARTAYGARGCNATHAARGAR---GCNCCNTCNCAYTCNCCNCARAGYGTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CCN ACNACNCCNTCNGAYAAYACNCCNTCNGCNAGYTCNACNTGGGAYAAYTGGCCNAAYGCN CCNCARGCNACNATGTCNGGNCCNAGYMGNCCNCAYACNATHAGYTCNGCNTAYGARAAR GGNCARTCNMGNCCNGCNYTNCARCCNGAYATGTTYGARCCNCCNAGYAGYGGNGTNGAR ATGMGNAAYAARTCNAGYMGN------------------GARTTYACNGAYGAYGARATH MGNCAYGARYTNGCNYTNYTNGGNTAYCAYGAYGTNCCNCARGAYAARYTNGARGAYTTY AARMGNGAYYTNATGCARYTNATHTCNAARGARMGNAGYAARTCNAAYTCNYTNAAYAGY AGYMGNATHACNGARACNGARGARGARGARGARAARCAYAARAARGAYMGNGGNYTNGAR GAYGAYGAR------------AGYTAYAAYAAYCAYGCNAGYCARGARGTN---GGNAAR AGYTAYMGNGARAAYTGGCAYTAYCARGGNGAYTTYATHTCNACNTAYTCNMGNMGNAAY GAYTAYTAYAAYYTNCCNCAR------------------TCNMGNTCNYTNACNTCNCAY GCNYTNGAR--------------------------------------------------- ------------------------MGNAAYCAYAGYTGYTGYGTNMGNGAYGAYATHGAR GCNAGYTCNGAYAGYMGNTCNATGAARMGNAARACNTCNMGNAARGCNTCNGAYGGNGGN MGNATGGTNGAYGARTCNTTYTCNGAYACNAAYGCNGGNYTNTTYGARATHTAYGARMGN ATHMGNAAYYTNGCNATGMGNGARTGYGARTGYGGNAARGAY---GGNACNMGNGAYACN CCNGARCCNCCNTAYMGNATHCAYGGN---AARAAYAARAAYCCNTCNGTNATHAARAAR AARGARCCNCCNCAYACNMGNAAYYTNATHMGNACNAAYATHAAYGARMGNCAYAARATG TAYAARGARGTNTGGAARGCNCARCCNCCNGTNGGNGARGAYMGNMGNYTNAARYTNMGN AARTCNGTNCAYGCNAARATGATGCARCAYCARGAYATHAARYTNAARCARAARATHTAY GTNCCNAAYYTNTAYGTNCCNCCNCAYGARAARYTNMGNAARGAYGTNMGNTGGAARGTN MGNCARGCNTTYGARAAYTAYGARYTNCCNCARACNGGNTTYTAYCAYGAY---ATGYTN AARGARYTNGAYATHYTNMGNGTNAARACNCARCARYTNCAYAARGCNAAYAARGARTGG AAYGAYCARTGGGAYMGNYTNAARCARGARAARGARAAYGARAAYYTNMGNYTNCAYGCN CARATHAARCAYYTNGTNCAYGARAAYGARCARYTNMGNAARAARATGGARTAYGCNATG GCNATHCARMGNAARGARYTNYTNCAYYTNAAYATGTCNAARCARGARYTNGARCARACN AAYAARGTNYTNYTNTCNGGNMGNGGNCARGARAARCARYTNYTNGARAARYTNMGNCAR GAYTAYGGNGCNYTNCAYCARGARAARMGNGCNYTNGARATHAARYTNGARGAYYTNACN AAYAAYAGYAAYATHGAYTCNCARAARGAYGAYTCNTTYAAYAARACNAARGARACNGAR YTNGCNGTNGTNAARMGNCARGTNACNYTNTTYATGGARGAYTTYAAYAARGARCAYGAR GARMGNYTNGARYTNGARAARAARYTNAARAARGARAARGARACNAGYCARAGY------ ------YTNGARACNAARYTNAARMGNACNCAYGCNYTNYTNAARTCNMGNGAYGARGAY YTNMGNCARAARTCNAARCARYTNGCNGARYTNCARTAYCARGTNGAYTCNYTNAARYTN AARYTNGARATHGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNTCNAAR GARAARTAYCAYTGYCCNTCNMGNYTNGCNCARACNTTYTCNGARATGGTNATHYTNGAY AARCARACNAAYAARTAYGAYTAYCAYYTNCCNYTNGCNCARTCNATHATHACNTCNATH ATHGAYCCNGARCAYTCNAAY------ACNGARGCNCCNYTNCCNCCN------------ ---CARCARTCNACNACNAARGARGCNAARGARATHATGAARATHMGNCAYAARAARATG AARAARCAYAARYTNAARAARYTNMGNAARMGNATGTAYTTYGTNTGGMGNAARCARAAR YTNACNMGNMGNGGNAARMGNGAYACNATHTAYTGGAARGGNATHTCNGAYATHAARAAR GARGGNGARGAYTTYGAYGCNGARACNTTYGTNAARGGNCARYTNGAYAARGCNMGNMGN GGNGGNTAYTTYATHAAYGTNTTYGARTCNMGNGTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNAARTGYATHATHTTYYTNTTYATHGCNAGYATHATHTTYCAYTGYATHGCNGTN YTNTTYGGNGCNCCNGTNAAYACNTCNGTNTCNGARACNTAYCAYTTYGCNGTNYTNYTN ACNACNYTNACNGCNYTNCCNTGYTGYGCNGCNGCNGGNCCNAARYTNGAYAARATGATG GARATHTTYACNTCNGAR---MGNGARCCNGGNYTNGARACNGTNGTNTAYYTNACNACN ATHGGNACNATHYTNGGNGCNTGGYTNGGNGCNGTNCCNATHCCNYTNGAYTGGGAYMGN CCNTGGCARACNTGGCCNGTNAGYTGYTCNATHGGNTCNGTNAGYGGNTAYTCNGTNGGN YTNTTYYTNGCNTCNYTNTAYATHCCNCAYGARTAYAARGCNGCNGTNAARCAYAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNGCNGTN GTNGCNGAYGTNGCNAARCARGCNMGNTGYGAYATHGTNATHGAYGTNGGNTCNGGNYTN GGNTAYYTNGAYCAYGTNYTNCAYCARGTNTAYGGNYTNAAYGTNYTNGGNYTNGARACN ATHCARAGYCAYGCNTCNGCNGCNGARAARMGNGCNGCNAAYCARGGNATHACNTGYGGN GGNATH------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TTYTGYCARCARTGYGTNCAR AAYTTYTCNMGNTCNGAYMGNYTNAAYATGAAYAARYTNYTNTCNGCNACNTTYAGYGAY CARATHAARACNGCNGCNAARAAYATHGGNCARAARYTNGAYATHATHTCNGARATGYTN TCNAARCARTGYAAYGCNGTNYTNGCNCARMGNATHMGNMGNTCNTAYCARGTNYTNYTN YTNTAYMGNAAYYTNTAYGGNGARMGNYTNYTNAARGARAARATGACNTCNCARATHAAY MGNATHAARAARAARCCNYTNYTNGCNGTNYTNTCNGCNTCNGTNTTYAGYTGGGAYMGN GARMGNGTNTCNGAYGARGARATHAARMGNTGYTAYAARGARGTNGAYGARGTNCAYYTN YTN------------AAYAGYMGNAAYATGTCNTCNGCNAGYTCNGAY------------ ---------------------------TCNAARGGNYTNMGNTGGGAYCARGTNGTNGAY AARGAYAAYTTYAARGTNTGGMGNMGNCARATHCCNAAYTCNGARYTNTTYCARTAYMGN GTNYTNGGNAGYTTYTCNGAYYTNCCNGCNMGNGCNTTYTTYAAYACNCARGTNGAYGTN CAYTAYTGGAARGTNTGGGAYGCNCARACNATGGAYGTNAARGTNGTNGAYMGNGAYGCN ACNTCNAGYTCNGARGTNATHCAYTGGATHTAYTCNTTYCCNTTYCCNATGTAYCCNMGN GARTAYGTNTAYGTNMGNMGNTGYATGATHAAYCCNGARMGNAAYAGYATGATHATHACN GCNMGNGCNACNCARCAYCCNAGYTGYCCNYTNAAYAARTCNTTYATHMGNATHGARACN TAYAARTCNCARATGATHATHACNCCNAAYAARAGYTTYGAYGARAAYGGNTTYACNTAY GTNATGTCNTAYGCNGAYGAYCCNCARACNAAYTTYCCNCCNTCNYTNTAYAAYTGGGTN GCNAGYTCNGGNGTNCAYGARTTYYTNCARMGNYTNCAYCAYGCNGCNATGAARAARCAY AARAAYATGCAY---ATGAGYAAYACN--------------------------------- ---------------ATGYTNYTNMGNYTNAARGARGTNATHCARTGGACNMGNATGACN GCNYTNGARYTNATGYTNCAYYTNGTNTCNTTYYTNGTNTTYTCNGTNYTNYTNGCNACN AARATHGARGGNGAYATHGAYATGTCNTGGTCNGCNGTNTTYTCNCCNYTNTTYATHTGY GAYGGNYTNAAYACNTAYYTNTGYGTNATHATHTTYGTNMGNCARTAYMGNGARTAYGAR YTNAARCARGCNTGYTTYMGNYTNTCNAAYTCNYTNTGYGTNATHGCNYTNATHTTYACN TTYAARYTNYTNYTNTGYCARAARYTNCARAAYGCNGGNYTNACNTGYTCNCARGCNTTY AGYCCNGTNTTYGTNYTNTCNCCNGTNTTYATGTTYMGNGCNTGYMGNATGCAYGAYGCN AARCCNYTNGARGARYTNCCNGARGTNGCNAARACNGARGARGTNAARMGNYTNGTNGGN ATHYTNCCNTAYGAYGARGAYGGNGARGAYGAYGARTTYMGNCCNGTNTGGGAYACNGAR TCNTGGGCNGCNGCNATHGCNGARTTYAAR---------------ATGGCNGAYATHGTN GARCCNCCNCCNTTYGARAAYGARGARGAY---GTNAARGARGARGAYGAYYTNTTYACN GAYGCNAARGARAARGCNTCNTCNCAYGAYGCNAGYCCN------YTNGAYGAYGCNGGN CCNAGYCCNTTY---------------GAYGAYAARGAYGAYGARGAYYTNTTYAARGGN GGNAGYTCNGARATHAARYTNGARTCNGAYGARGAYGAYGARGTNCCNGTNGGNAAYAAY AGYGTNYTNACNCARAAYCARTCNGCNGCN------------------------------ ---------GCNTCNTCNGTNCARGARGTNACNCCNGARATHTCNGTNTCNGARGTNATH ACNGCNAARACNAARATHGCNGCNCCNTCNYTNAARGCNGAYGARTTYTCN--------- GAYGAYAAYGAYGARAARTAYGAYYTNGAYATHAARATHACNGARAAYYTNAARATGGGN GAYGGNATGTCNGCNTAYATGGTNTTYAARATHGTNTCNAARACNACNAAYCCNGCNTAY MGNCAYCCNGARAAYACNGTNYTNMGNMGNTTYAGYGAYTTYYTNGGNYTNTAYGCNAAR YTNGCNGARAARCAYGTNCCNYTNGGNATHATHGTNCCNCCNGCNCCNGARAARAGYGTN ATHGGNATGACNAARGTNAARATGTCNAARGARGAYACNGGNTCNATHGAYTTYATHGAR MGNMGNAARGCNGCNYTNGARMGNTAYYTNATHMGNACNGCNGCNCAYCCNGTNYTNGCN GCNGAYCCNGAYTTYATHGARTTYYTNGARAARGAYGGNGAYYTNCCNAARGCNACNAGY ACNTCNGCNYTNAGYGGNGCNGGNGTNATGMGNYTNTTYCAYAARGTNGGNGARTCNYTN GARAARATHACNYTNAARGTNGAYGARAGYGAYGARTGGTTYGARGARAARCAYCARCAR GTNGARGCNYTNGAYGCNCARYTNAARAARYTNCAYTCNAGYYTNGARACNYTNGCNGCN CAYMGNMGNGARYTNGCNGGNAGYACNGCNYTNTTYGCNAARAGYGCNGCNATGYTNGGN AAYGTNGARGARCAYACNGCNYTNTCNMGNGCNYTNTCNCARYTNGCNGARACNGARGAR AARATHGARATHGTNCAYAARGAYCARGCNGARYTNGAYTTYTAYACNATGTCNGARYTN ATGAARGAYTAYGTNGCNYTNATGGGNGCNGTNAARGGNGCNTTYCAYGARMGNATHAAR GTNTAYAARCAYTGGAARGAYGCNGARACNATGYTNAGYAARAARMGNGARAAYAARGCN AARYTNGARYTNGCNGGNAARTCNGAYAARYTNCCNCARGCNMGNACNGARATHTCNGAR TGGGARCARAARGTNGARAARGGNCARGARGAYTTYGARAARATHTCNAARAAYATHMGN AARGARGTNGCNMGNTTYGARAARYTNMGNGTNTCNGAYTTYAARACNAAYGTNATHAAR TAYYTNGARGTNYTNATGGARAAYCARGARAARYTNATHAARTAYTGGGARACNTTYYTN CCNGARGCNCARGCNATHGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARGCNGCNATGMGN YTNAAYACNYTNCCNTCNACNATGAGYGAYGAYGAYTTYGAYTCNTCNGARAAYGAYMGN TAYGARGARTCNAARYTNMGNGAYYTNAGYAAYGAYCARCARAARGARGAYACNACNYTN AARAARGGNMGNMGNGTNTTYTTYTTYMGNAAYGGNGAYATHCAYTAYAARCCNAARCAR GTNYTNATHAAYAGYMGNACNTAYCARAAYTTYGARAARYTNYTNGTNGAYYTNAGYTCN ATHGTNGARACNTCNACNGGNGTNACNTTYATHTTYTCNTGG------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AAYGGNGAYGGNGAYMGNCARGTNYTNGCNCCNACN GARGGNCCNMGNGARGARYTNATHAAYACNGCNATHAARTTYYTNCARAAYCCNAARGTN ATGGARAGYCCNYTNTAYCARAARAARGCNTTYYTNAGYAARAARGGNYTNACNCARCAR GARATHAGYYTNGCNGTNGARMGNGCNGGNGTNAARGAYATHTCNAAYAGYGCNGCNGGN ACNGARGCNAGYYTNYTNCCNCCNCCNGGNTAYCARCCNGGNGCNYTNGCNCCNYTNCCN CCNAAYTAYGCNYTNCCN---TAYGCNCCNGTNCCNCCNCAYTCNMGNTGGGCNCARYTN MGNGGNYTNGCNTTYACNTCNGTNGTNGTNGCNGGNGTNTCNTAYGCNGTNTAYCAYYTN TTYAARACNTAYYTNGTNCCNYTNATHACNGGNTCNAARCARCARGARAARMGNATHGAY MGNYTNGARYTNCARATHGCNGARATHCAYAARTCNGTNAAYGARTCNYTNTCNGAYATH AGYAARACNYTNGCNGCNATHCARATGAGYGTNCARAGYCARCARCCNGCNGCNTCNCAR ATG---GTN---GGNMGNGGNATHACNGAYYTNAARGCNGAYATHTCNTCNYTNMGNAGY YTNYTNYTNAGYAARACNAAYGARGARCARTCNGAYACNGARCCNAGYATHTCNGCNAAR ATHGCNMGNTGGTGGMGNCARMGNAARMGNYTNGGNYTNTCNGTNCAYYTNCCNAARTGY AAYCCNGAYTCNATGYTNTAYCAYATHTCNMGNYTNCCNGARTGYTGYAGYTTYYTNAAR AARGARAARGARMGNYTNYTNAGYYTNYTNCARATH---CAYTGYAARAGYGCNAAYATH TAYGCNGGNYTNGCNAGYATHGARGAYTAYTTYGGNAAYTTYYTNYTNAGYYTNAAYTAY ATHCARCARGCNYTNGARYTNAAYCCNTCNAGYAARGAYTAYCARTGGTTYCARGCNAAR ATHTCNMGNCARTGYGAYACNYTNCARGARCARACNACNGCNAARGARMGNYTNAAYAGY AAYGARYTNCAYTTYCCNAARATHGCNGARATHCCNMGNGTNTCNGGNAAYAGYYTNAGY GTNTCNGARTTYAARGARYTNTAYATHAARCCNGGNAARCCNGTNATHATHACNGAYGTN GTNAAYAAYATGACNAARGAYTCNTTYGAYTAYTCNYTNATHGTNAAYCAYGCNGGNGAR ACNMGNGTNTCNACNAARCARACNTCNAARGAYTCNACNACNTGGGCNAARYTNGARAGY AGYMGNGARACNTCNATHTCNGARYTNGTNGARGGNATHCARAGYGGNTGYGTNAARGAY TGYYTNTTYGAYTGGAGYYTNCCNYTNCAYTGYCCNAGYYTNGAYCARYTNATHACNYTN CCNCCNTAYTTYCARGAYAAYATHYTNYTNCARACNTCNCCNGGNTCNYTNTAYMGNCAY AGYTGGCCNAGYYTNTTYATHGCNCCNGARGGNGCNGTNACNCARYTNCAYGTNGAYGCN TTYCAYTCNCAYTTYTGGATGGCNYTNTTYCARGGNMGNAARMGNTGGACNTTYTTYGAY GARMGNGAYACNTCNYTNYTNTAYCCNCARMGNTTYCARTCNATGGAYCCNGTNTTYGAR GTNGAYYTNACNCAYYTNGARGTNGAYAARTTYCCNYTNYTNTCNYTNACNACNCCNCAR CARTGYGARYTNCARCCNGGNGARYTNYTNTTYGTNCCNGCNGGNAGYCCNCAYATGGTN GARAAYYTNACNACNACNYTNGCNATHTCNTCNAAYTAYGTNGAYCARTCNAAYTTYGAY AARGTNTGYCAYCARYTNMGNATHAAYTCNYTNCARGAYGARMGNGCNACNGAYYTNYTN TCNCARYTNGARGAYCCNGCNTTYYTNAARMGN---------AARCARTGYGCNGTNATH GARTTYYTNYTNYTNGARGGNGARATHCCNAARAAYATHCAYATHMGNYTNAARAAYGTN TAYAARCARTAYACNYTNGAYTTYAGYAGYGTNTGYMGNNNNCARTTYCAR--------- ------------------ACNYTNTCNGAYAARCAYTGYTCNGGNMGNCCNTCNGTNTGY GTNAAYMGNGTNAAYMGNCARAARGCNGAYCARYTNGTNMGNGARAAYMGNMGNATHTCN ATHGAYAAYYTNGCNYTNGGNYTNAAYGTNAGYCAYGGNAGYGCNCAYTGYYTNATH--- GAYTCNYTNGGNTAYTCNAARGTNAGYGCNMGNTGGATHCCNAARCARCAYTCNCCNGAY CARAARAARGARMGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AGYMGNGTNGAYCARGTNTAYMGNAGYYTNYTNYTNTCNAARTTY TTYACNAARGGNTGGGGNAARCCNGAYAAYYTNAARMGNATHTTYGARTTYMGNAARATH YTNTCNAAYMGNGARTCNTGYCARACNYTNGTNGAYAARGAYTAYCCNATHAAYATHGAY AARGAYTAYAARGAYGGNGAYTGYMGNATHATGGARGGNCAYTTYACNTCNCCNTTYGTN CAYCAYYTNCCNGGNATHATGCCNAARGARGTNGARAARGCNAGYTTYCARGCNGTNYTN CCNYTNGARTGGCARCAYCCNACNYTNAARCCNATHTGYATHCAYYTNGCNGGNACNGGN GAYCAYTAYTTYTGGMGNMGNMGNYTNTTYACNGCNMGNCCNYTNYTNAARGAYGCNGGN ATHGCNTCNATHYTNYTNGARAAYCCNTAYTAYGGNTCNMGNAARCCNAARGCNCARYTN MGNTCNAGYYTNCAYAAYGTNAGYGAYYTNTTYGTNATGGGNGGNGCNYTNGTNYTNGAR TCNYTNGCNYTNYTNCAYTGGTGYGARMGNCARGGNTGGGGNCCNTTYGGNYTNTCNGGN GTNTCNATGGGNGGNCAYATGGCNTCNYTNGCNGCNACNAAYTGGGARAARCCNATHTCN YTNGTNCCNYTNYTNTCNTGGAGYACNGCNTCNTGYGTNTTYACNCARGGNGTNATGAGY GGNGCNATHCCNTGGCARGTNYTNCARGARCARTTYTTYAARAAYAAYYTNTAYCAYGAY GARATHAGYAARYTNATHGTNTCNCCNGARAARGCNTAYCARATGGGNCARCARTTYGTN ATHAAYTAYTAYGCNCARACNAARCARTCNCARCARTCNTCNAGYTCNTCNGARAARAAY AARAARYTNACNGCNGGNCAYGCNYTNGCNAARTCNAARATHYTNTTYTCNMGNAAYMGN ACNAARAARGARGARGARGARAARAARATGAARTCNYTNMGNGARGARTCNTAYGARTTY ATGMGNGGNGTNATGGAYGARTGYACNCAYYTNGGNAAYTTYTCNGTNCCNGTNGAYCCN GARYTNGTNATHATHGTNGCNGCNACNCARGAYGCNTAYATHCCNMGNGAYGGNGTNYTN CCNYTNGAYAARYTNTGGCCNGGNAGYGARGTNMGNTAYATHGAYCARGGNCAYGTNGGN GCNGTNYTNYTNCAYCARGGNGTNTTYMGNAARGCNGTNGTNGAYGCNTTYGAYAARCAR GTNAARAARTAYAARGAYAGYCAYGTNGGNYTNGAYTTYMGNGAYTAYTTYAGYGAYACN GGNGCNAGYAARMGNGTNTTYTCNAARGARAGYMGNTCNMGNYTNTGYGAYMGNGTNAAR AGYTCNATHTCNCCNGAYYTNMGNATGMGNYTNTGYGARGGNAAYAAYAARGTNTCNATH CCNGCNAGYATGAAYMGNGTNGGNAAYGCNAAYGCNATHGTNCAYGCNACNACNGCNGGN GTNMGNGARAAYGTNTTYTGYAARTAYAGYCAYMGNGAYTGYACNCARAGYTGYYTNGAR GGNTAYGAYCAYTGYATHMGNCAYATHYTNGARGAYAARTCNGCNCCNTAYMGNCARTGY GCNTAYGTNACNAARACNGGNMGNAARTGYCCNGCNGCNGCNCCNAARYTNGARAARAAR GARGGNTTYTGYGTNTCNCAYACNAARAARGCNYTNYTNGCNMGNCARMGNTTYTCNMGN AARMGNMGNCCNAARGARACNCCNGAYACNYTNYTNGARGAYYTNGTNGCNGCNACNTCN TCNATGGTNTCNAAYCAYGGNGTNGARCAYMGNMGNGCNAARGTNCAYAGYGAYAGYATH GCNGCNAARTGYYTNGARTAYGCNAGYTCNAGYGAYTCNGARTCNGARTCNYTNYTNGTN GARCAYGGNTGGMGNGAYTCNGGNGAYAGYGAYGCNGARAGYATHGAYAGYGAYCARGAR GAYATHYTNAARTAYGCNGGNGTNTAYACNACNGARGARGTNGCNCARATHYTNMGNGAY AARYTNATHMGNYTNCARGCNYTNTAYATHGAYCARTTYAARMGNYTNAARCAYATHYTN YTNACNAARMGNAARAARTAYYTNGAYACNGCNAARGTNGARAARGARYTNTAYGGNAGY ATHAARMGNTAYAARCARGAYCCNAAYCARAARGARYTNTAYGAYAARYTNMGNGCNATG AARMGNTAYCAYAAYAARTTYGGNATHGARAGYYTNYTNCARCARCARTCNACNCARMGN MGNATGAARGCNACNGARGGNATGGARGAYAARCCNAARATHGARATHAARTGYACNTTY ACNGAYGARGGNGTNGGNTGYCCNCARCCNGTNGTNCCNYTNAGYAARTTYTGYCARAAR CAYATHYTNCAYGAYCARCAYCARGTNYTNTAYCARCCNTGYCCNTTYGCNGAYAGYCAR TGYGGNMGNCCNGTNGCNACNYTNYTNGGNAGYCCNTTYTGYTCNYTNCAYCARGAYAAR GARAAYATHYTNTCNAGYYTNAAYGCNGCNAARGCNGAYAARCARAARGCNYTNGCNGGN TTYGARYTNAARGGNAGYGARYTNAAYAAYGTNYTNAARGARATGGARAARYTNAARGAR GCNGTNTCNTCNACNGARTAYMGNGTNAARTGGTTYCARAAYAARYTNAARGARGARYTN GAYGCNCAYAARGARACNAARTCNAGYYTNGAYAARACNACNACNAARYTNAARGARGCN AARGARGARACNGARATHATHMGNMGNGARTGYCARGCNATHGTNAARACNTAYCARGAR TCNGARGARATHAARTCNAAYAGYYTNGAYAARGARYTNAARATGAARGARTCNCARTTY MGNYTNCARACNCARGARTGGAAYGAYAAYCARCARGCNCAYGARAARACNAARYTNGAR YTNGAYGGNYTNAARGGNGARCAYCARCARGTNYTNGGNCARATHMGNACNYTNAARGAR AARAAYCARGGNYTNGARTCNATHYTNGCNGARAARGARTCNACNGCNAGYCARTGYAAY CARYTNYTNAAYAARCARAARYTNGAYATHTCNTCNYTNACNGCNAARGTNAARGARACN GARGCNYTNGARGARAAYTTYAAYMGNGCNMGNGARATGATHCARTCNYTNGAYCARGAR ATHTCNGARYTNAARATGACNAAYCARGAYYTNGTNAARGAYATGGAYGCNTGYCARCAR MGNGARTCNAARATGYTNGGNYTNCARTCNGARYTNAGYMGNAGYAAYGCNTGYYTNMGN TCNGARAAYACNACNYTNAAYAAYAARGTNTGYAAYCARACNGGNGAYGTNGARMGNATG AARATGGARATHCARCARYTNGAYACNTCNATHAARAAYYTNACNGAYGCNYTNGARGAR GARAARAARTCNAARGARCARACNGTNAGYTCNYTNAAYGCNTCNYTNAGYGCNAARACN AARGAYTGYACNGAYYTNAARCARAARTGGGARGAYGARATHGAYGCNAAYAARACNYTN AARMGNMGNCAYGCNAGYAAYGTNAARGAYYTNACNMGNCARYTNCARCARGCNAARMGN MGNYTNGARGTNATHGARGGN------AAYTCNGARGCN------ATGGGNTCNMGNTCN AAYTCNAAYGGNAGYYTNAAYTCNATGGCNGAYGGNAAYAAYATGACNCCNTCNGCNGGN GCNCARGCNTCNGTNCARGARTTYCCNGTNATHACNGARCARGTNGARATHGAYAARCAY GTNYTNATHGARMGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARGCNCAR GGNGGNAARGAYGARACNTTYCARACNTAYGTNTTYCAYGAYGARGAYCAYACNYTNGGN AAYGCNYTNAARTAYATHYTNAAYAARAAYCCNGAYGTNTCNTTYGTNGGNTAYAGYATH ACNCAYCCNTCNGARAGYAARATHAAYYTNMGNATHCARACNTCNGGNAARCCNGCNGTN CARGTNYTNMGNCARGGNYTNAARGAYYTNAARCARYTNTGYGGNCAYATGYTNACNACN TTYGARTCNTCNACNAARTAYTTYAARGARAAYCAYYTNGAY------AAYGAYATGGAY CARTCNTGYGCNAAYCARACNTGYCARAARATHTTYTCNGTNTTYGARMGNCAYCAYCAY TGYMGNAARTGYGGNGAYGTNTTYTGYTAYAAYTGYACNYTNTAYAARMGNMGNYTNAAY AARYTNGCNCAYTTYGAYCCNGCNGGNCARTCNTAYAARGTNTGYAARGTNTGYTTYGAR AGYGGNGCNYTNACNGARGGNCAYAGYCARAGYCAYACNYTNGCNTTYATHGCNATGMGN TCNGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARCAYGAYMGNMGNACNAARMGNCARTCNAARACNACNGARAAYGAY AGYAGYTCNYTNGCNTTYGCNGAYCARGTNACNGAYGAYGGNGCNACNTCNTCNAARGGN MGNGARAARATHGGNGTNCCNYTNGCNATGTGGGAYTTYGARCAYTGYGAYCCNAARAAR TGYAGYGGNAARAARYTNAGYMGNYTNGGNTTYGTNMGNACNYTNMGNYTNAAYCARMGN TTYGGNGGNYTNATHYTNTCNCCNGTNGGNACNAARTGYGTNGCNCCNGAYGAYMGNCAR TTYGTNGARGCNAAYGGNATGGCNGTNATHGAYTGYAGYTGGGCNAARYTNCARGARACN CCNTTYGGNMGNATGAARGGNGARAARYTNMGNYTNYTNCCNTAYYTNATHGCNGCNAAY CCNATHAAYTAYGGNMGNCCNTGYAARYTNTCNTGYGCNGARGCNTTYGCNGCNACNYTN TAYATHACNGGNTTYATHGARGARGCNGARATHYTNYTNAGYAARTTYAARTGGGGNCCN TCNTTYTTYTCNATHAAYACNGARYTNYTNGARACNTAYAGYAARTGYGTNACNAGYCAR GAYGTNGTNAGYGARCARAGYAARGTNYTNGCNMGNTTYCARCARGAYAGYATHGARGAY AARYTNAARGAYTGGATGGARATHGAYGAYGAYGCNAAYGTNTGYAAYCCNAAYMGNCCN ------YTNTAYCCNCCNTCN------------GAYTCNAGYTCNGARTCNGARGARGAR AGYGARGARGARGARGARGAYGAYAAYGARGAR---------------CARCARGTNATH GARAARAARGTNATGGCNTGYGCNATG------CAYGAYYTNCCNTTYATGATHCARYTN GCNGARTCNCARCARCARACNGAYGARGCNTCNAARGTNAAYTTYTTYTGYGAYCAYGTN TCNCARTTYGTNAARYTNGTNATGTGYACNATHAARCARATGTCNTCNTGYGTNCCNCCN GARATGAARCCNYTNYTNAAYMGNGTNYTNAARGCNGAR---MGNYTNACNGARGCNYTN AAYTTYYTNTGYGARGAYMGNTCNGTNYTNATGGAYAARTGYATG------------GAY GAYMGNGTNYTNCARTGYTAYACNGAYAAR---------ATHAARMGNATHATGGCNGTN GCNAARTCNACNGAYGAYMGNTCNCARYTNGCNTGYMGNGTNATHCAYGARGARGARAAR TGYYTNGTNGAYAAYAARGGNTCNTGYAGYGARGCNTAYGTNGCNAARYTNACNGGNTTY ATGGARAARYTNTTYTCNAARTCNGTNTGYGGNYTNGARCAYCARMGNCARATGAAYYTN ACNAAYAGYYTNGGNAGYYTNYTNGTNCAYGGNGTNCCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNGARTCNCCNGAYTCNGTNTCNGARAARYTNAAYTCNYTNYTNAAR TCNYTNCCNAAYTTYGGNCARCCNYTNTCNMGNMGNAAYAGYYTNGTNMGNACNGGNTCN YTNMGNGTNCAYMGNAGYTCNTCNYTNGAYYTNTCNTCNAARCAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNMGNGTNAAR AGYMGNAARTCNTAYAARACNGARCARGTNYTNTCNYTNCARGTNTAYAARYTNCARGAR GARAARCARAARYTNACNGARGARAARYTNAARGTNGAYAGYGARAGYGARTCNYTNAAR AARGARYTNCARGCNACNCARGCNGARYTNTCNGCNYTNMGNAARCARYTNGARATGAAR ACN------------GAYCAYGAYGGNYTNGAYTCNCCNGAYACNAAYGAYGARYTNGCN ATHAARAAYAARGARGTNATHAAYYTNCAYACNCARYTNCAYACNATHCARGTNGAYATG GAYAARAARAAYMGNGARYTNTGYGARAARACNAARGARYTNYTNAAYTAYAARGAYGAR GTNGAYAARYTNAARAARGARGTNGARAARYTNAARAAYCCNGCNGTNYTNTGYGARGCN TCNAGYCARACNCAYTCNGARAGYGARATHTCNAGYTCNGARAAYGTNAARCCNTCNATG ATGGGNGARMGNGARMGNACNATHCARACNYTNCARGARGARYTNGAYAARYTNAARAGY GAYGTNYTNGARATGGAYGAYMGNCAYGARMGNGARAARGARCARTGGYTNGARGARAAR AAYAARGTNATHMGNTAYCARAARCARYTNCARYTNAAYTAYGTNCARATGCARMGNAAR AAYTCNGCNYTNGARACNGARGTNCARCARYTNACNYTNGARYTNGARAAYMGNGAYATG AARYTNATHGCNYTNAGYGGNGARGARAGYGTNTGY------------------------ ---GCNGCNATHGTNAAYGTNGTNTCNYTNATHTAYATGCAYCARTGGCARCCNACNGAY GARTCNYTNGTNCCNTAYTTYATHATHATGGGNAGYTGGGGNGTNACNGAYGGNATHTGG ACNGCNCARGTNAAYAGYGTNATGGGNATHATHTTYCCNGARAARTTYGARGARGCNTAY GCNGGNYTNMGNATHACNCARGGNYTNAGYGCNGCNGTNGCNTTYGGNTAYTCNAGYATG YTNTGYATGACNTCNAARATHTAYATHACNATHATHGTNTGYGTNYTNGGNYTNGTNGGN TAYYTNATHATGGARGCNCARYTNAARTTYGGNAGYCARAARAARGCNGTNYTNYTNAAR CARACNTCNGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TAYGTNCCNTAYGAYGARGARYTNTCNGTNMGNYTN GARAAYGARTAYAARAARGCNATGGARACNAAYGGNTGGCAYMGNMGNYTNGARTTYCCN GGNAARGARATHATHGTNATGCAYAAYGCNAGYGTNATHGTNCARTTYGAYGARTCNTCN GCNCCNGAYCARTGGGGNAAYGTNATGGGNGAYCARAARMGNCCNMGNGTNGTNAARMGN GGNGTNGAYGAYTTYGCNACNATHGARTAYGGNGARMGNGARGARGTNGAYCAYYTNGTN TTYTTYGTNCCNGGNATHGARGAYATHGCNGAYGGNAARGARAARTCNYTNGARGGNTAY GTNAAYGAYTTYMGNAGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNTAYACN---AARCCNGGNTAYGCNMGNATHAARCARGAR TTYCAYYTNYTNAAYTAYAARCCNAARATHCARACNGARTAYYTNAGYGCNGAYTCNAAR MGNAARYTNGAR------GCNACNAARGAYGARCARAAYAARAARGARGAYGAR------ ---------------------GARTCNGARCCNCCNAGYAARAARACNAARYTNAARGGN MGNAAYAARCARMGNCCNMGNAAYGARAARATHGARCARAARGAYAARYTNTGYCCNGCN ATHAARGAYGGNMGNGTNTGYAARTTYGAYAAYAAYTGYAARTTYACNCAYGAYYTNAAR ACNTAYYTNGARAARAARATHCCNGAYATHGAYCARYTNTGYCCNGTNTAYGARAGYGTN GGNTTYTGYMGNCAYGGNATHACNTGYMGNTTYGCNAARAGYCAYYTNGGNGARAAYATG GARAAYYTNGTNAAYAARGAYYTNTTYGAYAARACNCARGTNCCN---MGNAAYYTNAAY ACNYTNACNGARGARGTNMGNAAYAARYTNTGGAARMGNAARTAYGAYTTYTCNAARGCN ATGAARTCNGTNAARAARATHCARAAYGAR---------------------TTYAAYAAR GAYACNAAYAAR---------------------------------------------AGY CCNAAYGARTCNACNAAYAAYACNGARYTNAAYGARYTNCCNAAYGCNTCNAARAAYTGY GARGAYGCNGGNYTNGARAARGGNGAYGCNGAR------------GAYAARGTNACNGGN TCNACNYTNGARACNTGYAARGAYAARAGYTCNAAYATHATHGARGCNTCNTCNATHCAR MGNGAYGARACNAARACNGTNGARGAYGTNTTYATHMGNCCNACNCCNMGNGARATHAAR AARATHGAYTTYMGNAAYCARYTNTTYYTNGCNCCNYTNACNACNGTNGGNAAYYTNCCN TTYMGNMGNGTNTGYAARAGYTAYGGNGCNGAYATHACNTGYAGYGARATGGCNYTNGCN TCNCARYTNYTNAARGGNAARGGNTCNGARTGGTCNYTNATHAARMGNCAYCCNAGYGAR GAYATHTTYGGNGTNCARYTNTGYGGNGCNTAYCCNGAYATGATGTCNAARTGYGCNCAR GTNYTNACNGARACNAGYGAYATHGAYTTYATHGAYATHAAYTGYGGNTGYCCNATHGAY YTNATHTTYAARAARGGNAGYGGNAGYGCNYTNATGGGNAARGCNACNAARYTNGARACN ATHTGYMGNAGYATGATHAAYGTNATGGGNGARAARCCNYTNACNGTNAARYTNMGNACN GGNATHTTYGAYAAYAARAAYGTNGCNCAYAAYYTNATHCCNMGNYTNMGNGAYGCNGGN GTNTCNYTNGTNACNATHCAYGGNMGNTCNMGNGARCARMGNTAYACNAARATGGCNGAY TGGAAYTAYATHGAYGAYTGYGCNAAYYTNGGNTCNCCNATGCCNGTNTTYGGNAAYGGN GAYGTNYTNTCNTAYGARGAYGCNAAYYTNCAYATGAAYAARAAYCARATHTCNGGNGTN ATGATHGCNMGNGGNGCNYTNATHAARCCNTGGATHTTYACNGARATHAARGARCARMGN CAYTGGGAYATHTCNTCNTCNGARMGNTTYGAYATHYTNAARTCNTTYTCNAAYTAYGGN YTNGARCAYTGGGGNTCNGAYCAYCARGGNGTNGARACNACNMGNMGNTTYYTNYTNGAR TGGYTNTCNTTYYTNCAYMGNTAYATHCCNGTNGGNGTNYTNGARCARGTNCCNCARAAR ATHAAYGARMGNCCNCCNTAYTAYATHGGNMGNAAYGAYYTNGARACNYTNATGGCNAGY ACNAAYTGYGCNGAYTGGATHAARATHAGYGARATGYTNYTN------------------ ------------------------------------------------------------ ACNGARATHATHYTNGARACNATHGAYCAYYTNMGNAARMGNAARGCNMGNCCNGAYYTN CARMGNATHTGYCAYATHGTNAARMGNMGNTTYGGNYTNCCNGCNAAYCARACNGARGCN AARYTNGARAARYTNGTNGAYGCNGARATHGTNATHAARGTNGAYTAYAARGGNAGYACN AGYTAYMGNAAYGCNTCNAARTGGMGNAARAAYYTNATHGGNTGYGCNATHCARAAYTCN ACNACNGTNACNACNAARATHATHGARGCNATHTAYGCNYTNTCNAARACNAAYACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGAARACNCARMGNGGNAARACNGGNMGNAARAAYGCNAGYTCNCCNTGY YTNGARCCNGTNTCNGTNTTYTGYMGNATHMGNCCNYTNGAYGAYCCNAAYGARYTNACN TGYATHAARCCNYTNGCNGAYAAYATHATHCARYTNCARACNCCNGARAAYGCNCCNGCN MGNAAYGGNCARATHAARGARTAYCARTAYACNTTYCARCAYGCNTTYGAYGARTGYTCN TCNCARAARACNGTNTTYAAYCARACNGCNYTNCCNYTNGTNGARGAYYTNYTNYTNGGN AARAAYGGNYTNYTNTTYACNTAYGGNATHACNGGNTCNGGNAARACNTAYACNATGACN GGNTTYCCNCARGAYCARGGNATHYTNCCNMGNTGYYTNGAYGTNYTNTTYAAYAGYATH GGNGARMGNCARGCNAARAARTAYGTNTTYMGNCCNGAYCAYATGAAYGGNTTYGARGTN CARAGYGARGCNGAYGCNATGATGGARMGNCARAARAARGAYATH--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARTTYCARGARATHGARAARGARYTNGARCAYYTNMGNAARAARYTNCARGAYAAR GAYGTNATHGTNTCNGAYYTNCARMGNTCNAAYTCNTCNYTNYTNGARYTNATGGAY--- ---------AARAAYAGYGAYCAYAAYGARMGNYTNGCNGTNCAYAARYTNGARGCNGAR YTNMGNAAYYTNMGNGCNGARMGNGARCARATGGTNGCNGTNGTNAGYGARAARTCNMGN GARAAYTCNTCNYTNAARTCNGARATHCAYMGNYTNATGGARYTNGTNTCNGCNGGNCAR GCNGCNYTNGCNAARTCNCARCARGAYAAYYTNACNYTNGAYCARACNAARCARATHAAR ACNTGYAGYAGYGAY---GAYGAYGAYGARATGAARMGNGARGCNYTNAAYAAYATGGCN MGNYTNATHMGNGAYAARGAYACNGARATHGARGCNYTNATGCARAARAAYCARACNYTN YTNTCNGTNYTNCARGARTCNTCNTCNCARTCNGCNGCNGCN------YTNGGNCCNATH YTNAARGARAARGARGCNYTNGCNCARCARGTNAAYACNYTNGTNTCNGARMGNGARCAR YTNATHGCNTGYATHACNCARAARCAYTCNGARTCNYTNGCNTTYCAYGCNGARGTNCAR MGNYTNACNTCNGTNATGGTNGARACNCARGARGCNGCNGAYAARATHAARGCNGARTAY GCNGCNYTNATHCCNTCNTTYGARGGNAARGCNAARTCNYTNYTNAGYGTNCARCARGAR YTNGTNGARTGYMGNCARAARYTNAARGARYTNGARATHAGYCAYGGNGARYTNATHCAR MGNTCNAAYTCNCARGCNGTNGAYGARYTNGARGCN------------GARATH------ ------------------GARAARTTYAARGCNYTNGARAARGAYCAYAARGCNACNATH YTNGARCARAGYAAYCARATHCARAGYYTNACNCARAARYTNAAYGGNGTNGARGAYGCN GTNGCNTCNAARCARGCNGARTGYGCNCAYYTNAARAARCARYTNGAYAAYAGYAARTTY CARYTNACNGGNYTNATGGCNGARATHGCNGAYGCNAARTCNGARAARGARYTNGTNMGN CARAARAGYGARTCNCARGGNGARGARTCNCARCAYYTNMGNAAYAGYYTNAAYCARYTN ACNYTNGCNGTNAARGAYAARGAYGTNGARATHTCNGCNYTNAARGARCARYTNTCNACN GTNAAYTCNGTNYTNCARAAYAARAARGGNCARCARGAYCARGTNTCNCARYTNATHMGN GAYCAYGARYTNGCNYTNGCNAAYAGYMGNCARYTNCARCARGARAARGAYTCNAGYGTN ATGYTNGCNGAYCARMGNYTNCARGARTGYCARGCNYTNAARACNGARYTNTCNTCNCAR AARGAYAARGTNTTYAARYTNGARMGNGARYTNGARMGNYTNMGNAGYCAYYTNYTNGAR ATHGARGARGGNTAYACNAAYGARGCNYTNGGNGCNGARGARMGNGARAARGARYTNMGN AAYMGNYTNGCNGTNGCNGARGARCARYTNGCNTCNTCNTCNTCNCAYGTNAARYTNGCN AGYCARGARGCNCARMGNCARATHGARAGYYTNGARTCNCARYTNCAYACNATHGCNAGY CARMGNGAYGCNGCNTAYATGCARGTNGCNTCNACNCARGARCARTGYCARCARTAYGCN TCNTCNYTNACNAAYYTNCARYTNGTNYTNGARCAYTTYCARAARGARAARAAYTCNGCN ATHGCNYTNGARACNGARAARTAYCARGARCARGCNAARTCNYTNGAYAGYAARGTNAAR GARYTNGARAARGARYTNAAYGCNACN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TGY TTYGTNCAYATHACNAARGTNMGNGCNTGYACNGARCARAGYGGNYTNATHTGYAAYTCN AARCARCCNATHGTNGTNGCNTGYTGYAARGGNGAYTAYTGYAAYGARAAYYTNACNATH CCNGCNCCNCCNGARGARAAYCCNGTNGGNGCNGARGAYGCNYTNACNAARACNTCNATH ATGATHGTNATGTGGGTNGTNGTNGCNGTNACNATGGTNATGYTNGGNTAYATHATHTTY MGNATHMGNMGNGGNMGNCARAARAARAARGGNYTNGGNTCNATHYTNTCNGARAAYMGN YTNYTNGARTCNGCNAGYGGNAGY---AARGGNTTYATGGTNGAYCARACNTCNGGNAGY GGNTCNGGNCARGCNAAYYTNGTNATHMGNACNGTNGGNAARGARGTNGARYTNATHGAR AARATHGGNAAYGGNMGNTTYGGNGAYGTNTGGMGNGGNAARTGGYTNGGNGAYGAYGTN GCNGTNAARATHTTYACNTCNYTNGARGARACNAGYTGGMGNCARGARATGGARATHTAY AAYACNGGNATGYTNMGNAAYGARAAYATHYTNGTNTTYCAYGCNTCNGAYACNATHGGN MGNTTYTCNTGYACNCARAAYYTNYTNATHGTNCARTAYCAYCCNAAYGGNTCNYTNTAY GAYTAYYTNCARMGNAGYGAYATHGAYATGGARGARATGYTNGTNYTNGCNCAYTCNGCN GCNGCNGGNATHAGYCAYYTNCAYTAYGARATHAARCARGGNATGGGNACNCAYGARAAR CCNTCNATHGCNCAYMGNGAYATHAARTCNAARAAYATHYTNGTNAARYTNAGYGGNGAR TGYTGYATHGGNGAYYTNGGNCAYGCNATHAARAAYACNAARGARTGGGAYMGNGGNMGN GARMGNYTNTGGGTNGGNACNMGNMGNTAYATGGCNCCNGARYTNYTNGAYAARACNYTN AAYCCNGCNCAYTTYGARTCNTTYMGNTGYGCNGAYGTNTAYGCNTTYGGNYTNGTNATG TGGGARATHGCNMGNMGNGCNMGNCCNTAYTGYGARGARTAYMGNGTNCCNTTYTGGGAY YTNGTNCCNGGNGAYCCNAGYYTNGARGAYATGAARYTNGTNGTNGTNGAYMGNCARCAR MGNCCNGTNATHCCNAAYAAYTGGTCNCARGAYCCNACNATGCARGARATGGARAARYTN ATHACNGGNTGYTGGACNCAYCAYCCNTCNAGYMGNYTNAARATHYTNMGNGTNAARAAR AAYYTNCARMGNYTNYTNGCNGCNACNGARCAYAAYCAR---GAYAARMGNGAYYTNTCN GGNAARAARATHYTNGAYGGNAGYACNACNGCNAAYAGY---------AAYAGYGTNATH ATGYTNTTYGAYYTNAARGAYTGGGARCARGGNACNGAYYTNYTNTGYGARGAYYTNAAY ---------YTNTTYMGNGAYCAYTTYGAYTGYYTNAGYCARTCNTCNACNMGNATHTCN AGYTGYATHYTNATHMGNACNCARACNTTYMGNMGNACNATHYTNGARGCNGGNATGTCN ACNCAYMGNACNYTNCAYGAYATHACNTGYAAYTTYGCNGARAAYATHGTNAAYTGYYTN GARTAYCCNYTNAGYAARCARTGYCCNGTNTCNGTNGTNGAYACNATGGTNGCNGCNYTN CAYMGNTTYYTNCCNCCNGCNTGYGCNCCNYTNCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CARATHAARTAYTAYGARYTNAARAGYAARATHTTYGTNGGN AGYCCNGTNACNGARATHAARAAYGCNACNATGCCNATGMGNACNAAYYTNAARCARCAR YTNCARMGNCARCARYTNTAYGAYCARGARAARMGNCARAAR------GGNAAYGGN--- ------ACNGCNTCNATGGGNATHGAYGTNCCNAAYCARTCNGARAAYAAYACNGTNCCN TCNAAYATHYTNCARGTNMGNACNCARYTNCARCAYCCNACNAARTAYCAYGTNMGNCAR AARCARAAYCARCARGTNCARAGYTTYYTNCARGARCARGTNCARGARCARYTNCCNATH CARTCNYTNCCNTCNAAYYTNATHACNACNTCNCARCARCARCARCARCAYCCNTTYYTN CARACNTCNAGYAGYGCNCCNGAYCCNGAYATHTCNAAYCCNYTNATHGAYGGNTCNATH AGYGGNGCNGARTTYATHCCNAGYAAYTTYGAYYTNYTNGGNGAYYTNAGYTCNGTNGAR CARYTNGARYTNGGNAAYATHYTNAAYGAYAGYGAYYTNATHGARATHCARCCNTCNYTN GGNACNGARGGNYTNAAYCARAAYGGNGTNGTNTCNAGYTAYGAYACNYTNGARGCNGAR ACNGCNACNGTNGCNGTNAAY---------TCNTGYCCNACNACNAAYTAYYTNAGYCAR GAYYTNGCNCAYACNGGNATHATGTCNGTNCARGAYGARATHTGGMGNAARGARMGNATH AARAARGAYAAYCAYAAYATGATHGARMGNMGNMGNMGNTTYAAYATHAAYGAYMGNATH AARGARYTNGGNGGNYTNYTNCCNAARTCNATGGAYCCNGAYAAYMGNCARAAYAARGGN ACNATHYTNAARGCNTCNGTNGAYTAYATHAARGCNYTNCARGAYGARCARAARAARGTN MGNGGNATGYTNGAYGARAARMGNAARGCNGARYTNGAYYTNMGNAARGTNYTNATHMGN YTNAAYCARATGAAYYTNGTNYTNAARTCNCAYGGNATHGAYTCNGGNGGNYTNGARGAY YTNGARYTNTCNTCNAGYGTNGCNTCNAAYCCNTCNAAYTTYYTNACNTCNCCNGTNCCN TCNACNCARYTNCCNACNYTNACNAAYAAYACNATHTCNAAYCAYCARGTNYTNTTYTCN AGYAGYGTNATGGAYGAYYTNATGGAYGAY------TCNCCNGTNAGYGGNGAYCCNATG YTNATGTCNGCNCCNGTNAGYCCNGARCCNGAYGARGTNGGNTTYCAYTTY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGGARCARYTNCARAAYGCNYTNAAYGCN TAYGGNCCNAAYTCNCARCAYTTYYTNAARGAYTCNGTNTCNAGYCCNTGGGARMGNGCN GTNGCNGCNAAYAARGTNCCNTAYTTYATHAAYCAYGAYACNGARACNACNCARTGGGAY CAYCCNCARYTNACNGCNYTNATGGAYGCNYTNATHGAYYTNAAYAARATHMGNTTYGCN GCNTAYMGNACNGGNATGAARYTNMGNATGYTNCARAARAARYTNTGYYTNGAYACNGTN TCNYTNCARATGGCNATGGARGCNTTYGAYAGYCAYGGNYTNMGNGGNMGNAAYGAYAAR YTNATGGAYGTNGGNGARATGATHGARTGYYTNTCNACNATGYTNGARTCNGCNGCNAGY CARCAYCCNGAYTTYGTNAGYGTNCCNYTNTGYGTNGAYYTNGCNYTNAAYTGGATHYTN GAYGTNTAYGAYAGYGTNMGNAGYGGNAARATHMGNGTNYTNTCNTTYAARGTNGCNATG GTNATHATGTGYAARGCNCARYTNGARGAYAARTAYMGNTAYYTNTTYMGNYTNATHGCN GAYACNAAYGCNTTYGCNGAYCARMGNAARATGGGNYTNYTNYTNCAYGAYTGYATGCAR ATHCCNMGNCARYTNGGNGARATHGGNTCNTTYGGNGGNAGYAAYATHGARCCNAGYGTN MGNAGYTGYTTYGARAARGCNAAYGGNMGNCCNGARATHGARGCNTTYCAYTTYYTNGAY TGGYTNAARYTNGARCCNCARTCNATGGTNTGGYTNCCNGTNYTNCAYMGNYTNGCNGCN TCNGARACNGCNAARCAYCARGCNAARTGYAAYGTNTGYAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARACNGARTCNTCNAGYACNCCNAGYMGNATHAAYAAR GCNGTNGAYTAYYTNCAYCARTGGCAYAARAAYMGNAARACNTGGAARTTYAGYAARAAY TTYCARACNYTNYTNATHAARGCNYTNTAYAAYCCNGTNATHATHGGNGAYGARGAYTTY GGNACNYTNYTNYTNTAYYTNGARGARAGYAARGGNYTNGCNMGNGARAARGTNYTNACN GAYGCNAARGCNYTNGTNGAYGTNGARGARGAY--------------------------- ---------------------------GARYTNTTYGGNTTYACNGGNTGGGCNCAYTCN ATHAGYAAYCARACNGTNGAYTTYGTNGAYCAYATHAAYGGNAARTAYTAYGTNGGNGTN TCNGCNACNGTNAARGTNACNYTNAARAGYGGNGTNTTYCAYGARGAYGTNGGNTAYGGN GTNAGYGARGGNATGMGNTCNAARGCNYTNTCNYTNGARAARGCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATHCCNACN CARTCNTTYMGNGGNCARATHGAYGTNACNGCNAAYTGYAARCAYATHTAYGAYGAYATG GARAARTCNTAYAGYCAYMGNGARAARTCNATHCARCAYTGYATHMGNYTNGTNAGYGAR GGNGTNAARAARGTNAAYGARAARMGNCARCARGAYCCNGAYAAYYTNGTNYTNATGAAR TCNYTNMGNGCNGARCARACNAARYTNMGNYTNATGCARCARGARATGAAYATHGARGAR GTNGTNAARGAYMGNACNTAYAARGTNATHACNGAYGTNTGYGTNGARATHGCNGGNYTN TGYCAY------------------------------GAYYTNGGNCAYGGNCCNCAYTCN CAYATGTTYGAYGGNAARTTYATHCCNGTNGCNCCNAAYAAR---AARTGGACNCAYGAR GARGCNTCNATHATGATGYTNGAYCAYATGATHAARGARAAYGGNYTN------AARGAR ACNGTNYTNCAYCAYCAYGGNYTNMGNGARATHGAYATHACNTTYATHAARGARYTNATH TAYGGNCCNYTNACNAAYGARGARTGGGAYTGGCCNTAYCARGGNMGNGAYCARAGYAAR TCNTTYYTNTAYGARATHATHTCNAAYAARATGACNGGNATHGAYGTNGAYAARTGGGAY TAYTTYGCNMGNGAYTGYTAYCAYYTNGGNYTNGTNAAYAAYTTYGAYCAYAARMGNTTY ATHAARYTNGTNMGNGTNYTNGARGTNGGNGGNMGNYTNMGNATHTGYGCNMGNGAYAAR GARCARGCNAAYYTNTAYCARATGTTYCAYACNMGNTAYAAYYTNCAYMGNATGGCNTAY CARCAYAARGTNGCNAAYGCNTGYGARGTNATGGCNGTNGAYGCNYTNGTNAARGCNAAY GAYTTYATHAARTTYMGNGGNAGYAAYGGNTCNTTYAARYTNTCNGARTGYATHGAYGAY CCNAARGCNTTYGARCARYTNACNGAYCAYGTNATHTGGCARATHTCNAAYGARATHGCN ------YTNACNCCNGCNAARAAYATHATHGARAARATGTTYMGNMGNAARYTNTAYMGN TGYYTNGAYGARMGNCARTCNAGYYTNGCNAARACNCARACNYTNGAY------ACNYTN MGNGAYCARATGGTNGARATH---TCNMGNAGYATHAAYAARYTNYTNCARAARACNGAY TTYAARYTNCARATHGTNTAYATGGAYTAYGGNAARAARGARAARAAYCCNYTNACNGAY ATGTGGTAYTAYTCNAARAARGAY------------------------------------ ------------------------------------------------------------ ------------------------------------GCNATHYTNGCNYTNYTNYTNYTN TCNACNGCNAARCCNGTNMGNCCNAARCAYGAYAARCCNGARCCNGTNGARGGNAARTCN CCNGAYGAYAARGGNCARGARTCNYTNGGNYTNGCNTAYGARCAYTAYYTNAARGARGTN GTNGAYGTNYTNGARAGYGAYCCNGARTTYAARAARAARYTNGARACNGCNAAYGTNACN GAYATHAARAGYGGNAARATHGCNATGTAYYTNGAYATGGTNAAYCAYACNGTNMGNAAY GTNYTNCAYGARYTNAARMGNAARGARGTNTCNMGNYTNACNCAYYTNGCNCARYTNCAR ATGAARGCN------GGNGTNAARAARTTYGARATHCCNGAYCAYYTNGAYYTNGGNAAY CARCAYACNTTYGARGTNAARGAYYTNGARAAYYTNATHAARAARACNACNTCNGAYYTN GARAARYTNGAYGCNAARMGNMGNGARGARTTYAARGARTAYGARATGGARAARAARTTY GARGARGARGARCAYYTNAARCARYTNAGYCCNGARGARAARAARAARGARGARGARCAY YTNAARCARYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ACNAAYACNYTNTCNAGYATHAARMGNAAR ATHGARGAYYTNAARMGNAAYGCNAARCARMGNAARYTNAAYGAYMGNACNGCNGTNATH ACNAGYACNGAYAAYAAYATHGCNGTNGAYAARGGNACNACNGAYCARTTYMGNCARCAY ACNGTNACNATHAARTCNGCNGARGARMGNGCNAARAARTCNTGYYTNGARGCNTAYCAR GTNTAYAAYTAYTGYACNMGNYTNTTYMGNTTYAARACNATHGCNGTNAARAARTAYMGN ACNTGGMGNGARMGNMGNAARCAYATHAAYGARATGAAYMGNYTNAARMGNCCNCARYTN CCNAAYGAYACNAARYTNATHACNTGYCCNGTNGTNGGNGARAGYAAYAAYAGYATGATG AAYGGNGGNAARMGNGARTTYATHYTNAAYCCNGCNAARAARTCNTAYYTNTGYATHYTN CAYGARTAYYTNCARMGNACNTGGAARATHAARCCNGGNTAYGTNTTYAARGARYTNGAR AAYTCNAARACNCCNTAYAGYGCNACNGTNACNGTNAAYAAYATHGARTAYGGNACNGGN YTNGCNTCNTCNAARAARGTNGCNAARCARGARGCNGCNAARGARGCNYTNAARATHYTN ATHCCNGAYATHCAYGARAARYTNTCNGAYCARGAYYTNAARACNCCNGTNTCNGAYTTY TCNTTYTTYGAYGARATHCARATHGARGAYCCNMGNGTNTTYGARYTNGGNAAYAARGTN GGNCARCCNAGYCCNTTYCARYTNYTNGGNGARTGYGTNMGNMGNAAYYTNGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGGTNGCNTTYGGNYTNCAYYTNGGNGCNTGY TCNGCNTGYGTNGCNGTNCAYAARGAYGGNAARACNGARGTNATHGCNAAYGAYYTNGGN GAYMGNGTNACNCCNGCNGTNGTNGCNTTYACNGARCAYGAYATHTCNGTNGGNGCNGGN GCNAARCARGGNGCNGTNMGNAAYGCNGCNAAYACNGTNATGCAYGTNAARCAYATGATH GGNAGYCARGARGARGAYGAYCARGTNAARGARTAYATHCARAAYCAYCARGTNGARGTN ACNTGYCARAARGGNTGGGTNGGNTTYAAYGTNGARTAYCARGGNAARAARGTNGTNTAY TCNTCNAGYAARATHYTNCARYTNATHTAYGGNAARATGYTNGARACNGCNCARAGYCAR AGYGGNAGYGGNACNACNGAYGCNGTNATHGCNGTNCCNTCNGAYTTYTCNCCNGCNCAR MGNCARYTNYTNAGYGAYGCNGCNACNTCNGCNGGNTTYAARGTNYTNMGNGTNATHAAY GARCCNTCNTCNGCNATGYTNGCNTTYGAYGTNGGNCARTTYGAYGARACNGARCAR--- TTYAARGTNYTNGTNTAYMGNTTYGGNGGNACNTCNCAYGAYGCNACNGTNGTNAGYGTN GARCAYGGNATGTAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CCNGAYTCN TTYAGYGTNTCNTTYCARGARATHGARGTNYTNTTYAAR------------------AAR GTNYTNAGYTCNAAYAAYGGNACNTGGCAYTAYGAYTTYAARAAYAARMGNGCNMGNTAY GAYCAYAAYMGNGGNCARACNAAYAAYTTYTGYGAYGGNCARAAYYTNAGYCCNAARGAY CCNMGNGCNGAYTGYCARYTNTTYTTYACNCCNACNGAYGAYYTNATHGTNTAYTAYCCN GGNACNAARAAYTGYTGYMGNYTNTGYGGNAARAARGARGGNTGYACNATHYTNAARCCN GAYTGGYTNAARCARGAYTCNCAYGCNGTNAAYTCNGARACNATHAAYGGNATGMGNTGY TAYGGNTGGGCNAARAARGGNGCNGTNACNGCNGCNGAYACNTGGTAYGARTCNGCNACN GGNGTNCCNTGYMGNTAYCAYGARGAYATHTAYCAYATHATHCAYAAYYTNACNTTYATH GCNGAYACNTTYAARGTNGGNCCNYTNGAYTCNGCNGTNTTYGAYGTNCCNTCNTAYTGY AAYAARACNTGYCCNCAYCCNTAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TTYMGNAGYATHAGY GAYYTNGGNAAYCCNGTNAAYGARYTNGTNMGNYTNGTNMGNGTNTAYTCNACNCCNTGG GARGARAARAGYGCNGCNYTNAARAARYTNCAYGARGAYTAYGARAGYAARCARMGNCAR YTNAAYATHGCNGTNMGNMGNYTNCARYTNGTNGAYGCNCAYTCNAARMGNGTNGCNAAR GARAARMGNATHATGAAYTGGGARAARYTNTTYTCNAARATGACNACNGCNAARGGNCAY GGNMGNMGNTGGAARTTYYTNATHGARACNATHAARCARAARGCNAARYTNGGNYTNGAR CAYGTNCARGCNTAYACNCARAGYYTNGAYGAYTCNTCNGARTCNGARACNGARGARGCN CCNACNGARCARGCNGCNACNGTNGCNACNMGNGAYATHGAYGAYACNAGYGARACNCAR GGNTCNCARGGNYTNGARGGNACNGARGGNAGYGCNAAYGARGAYGARGARGARGARGAY GAYAAYGAYGAYGAYGAYAAYGARACNGCNGARGGNMGNGGNGAYGARMGNGARGAYATH GAYTCNMGNGTNAGYGGNGARACNGARAAYACNGARGARGAYCARACNGAYGAYGCNCCN ACNGTNTCNATHCARATHGGNCCNGGNGGNGAYACNGAYGTNGARMGNATHTCNYTNMGN TCNGCNTCNCCNAARAARGTNMGNTTYGARGAYAGYGTNACNAGYACNGCNTAYATHMGN CCNCCNATGCARGAYTCNACNACNTGGACNGGNCARCCNGAYTAYGAYMGNTTYYTNTTY YTNMGNATHTTYTGYCCNGARGGNATGGARCARATHGGNACNGGNATHAARTGYTCNYTN TCNTAYGAYGGNAAYATGTTYAARACNCCNATHYTNGAYTCNCCNGARGARCAR------ ---ATGGARGARCCNGAYGTNATHGAYGARMGNCCNACNCARMGNCCNCARGCNGCNMGN AARTCNGAYGAYMGNGCNAAYGTNGAYATHTCNCARGARACNGAYTCNGCNAARAGYAAR AGYAARMGNTAYTTYGARTTYGARATHCCNYTNCCNGAYGAYGTNATHGARGGNYTNYTN YTNYTNGGNGARAARCCNCCNCCNGARCCNGARAAYATHMGNATHGCNGTNCAYCARGGN CARTTYGARGARATHATHGCNATGGCNACNATHGAYTTYCARGAYATHAARGCNYTNAAY YTNGARACNGTNTGGYTNCCNGGNCCNGTNGGNGAYGAYGAYGTNGCNAAYATHAARTCN MGNTCNAAYTCNYTNAGYGTNACNTCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TAYMGNGGNYTN AAYAARAARTGGGARACNCAYCARYTNGCNACNATGAARTCNGAYACNACNTTYGAYGCN MGNAGYCARGTNACNCARCCNCCN---------TTYTCNGTNYTNAGYCAR---MGNGGN GCNACNACNCARTAYTCNMGNTCNTAYACNGARACNTAYTCNMGNAARGGNGCNCCNMGN ---AGYGARGAYGGN---TCNAGYGTNTAYGAYCAYGARACNAARTTYTCNCARAARAAY YTNATGAAYGAYGARMGNGAYMGNMGNMGNGAY---MGNCAYMGNATGGCNTCNCAYAAY GAYTTYGAYGAYGAYGAYGARGAYCCNAAYAAYTTYAARGARAARGTNATHACNCCNMGN TGGAARCCNCARGAYMGNAARAAYMGNMGNCCNCCNTCNTTYGARGARGCNACNMGNGAY AGYTCNMGNGARMGNTCNTCNGAYGARGGNTCNGGNGAYGARACNCARACNGAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARAAYTCNCCNCCNATHAARATHTCNMGNATGGARAAYGCNATHCARTCNGARTAY CCNMGNYTNGTNGGNGARYTNGTNCARGCNYTNCCNCAYGTNCCNYTNGCNTCNTTYGTN GARTGGTTYATHGARACNTCNCAYCCNGGNCARTTYACNGGNTCNGARGCNTCNGCNTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNAARGARYTNGAYGARYTNCAYGARAARMGN GARATHGGNYTNATGGARAGYATGTAYACNYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GCNMGN CARTAYGTNTGGTTYAARGTNATGGGNCAYATHGGNAARTTYTTYATGACNTCNATHGAY CAYAGYATHTGGTTYCAYCAYCCNGTN------------------------------AAR GARATHMGNTTYAARMGNACNGCNGARGCNYTNCARAARTCNGGNYTNTGGGAYATHGCN ATGAARACNGGNCAYYTNATHAARCARAAYCARGARYTNCARATHGARYTNGARCARTTY AARATHGAYGCNYTNAAYTTYYTNAARTCNGTNATHAARAAYCCNYTNAAYMGNGAYYTN ATHAARYTNGTNYTNAAYAAYGCNYTNYTNAGYTCNGCNGARGGNAARAARCCNTCNGTN ATGAGYATHGTNGTNTCNGTNGCNATGCCNCCNCCNGARMGNTGGGARGCNTAYACNAAR ATGGGNAARGTNATHGARGGNACNGCNATHATGCCNATHAARGTNCCNYTNAARGARCAY TTYACNAGYTCNYTNCARGARGARGARMGNTTYTCNCCNTAYTCNYTNYTNGAYYTNATH AARGARCARAAYYTNACNYTNGGNGGNATHGTNGAYYTNACNTAYACNACNMGNTAYTAY GAYAGYCAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TCNYTNTCNGGN AARGTNGTNTCNMGNATHATHGTNCARGTNGGNGARAAYCAYAARYTNYTNTGYCCNGCN AAYTCNGAYCCNGCNYTNACNCARTGGAARAARAAYGGNMGNGCNYTNAAYCCNGGNTGG GARMGNTTYAARGTNTCNMGNGAYGGNAAYYTNAARATHMGNAAYGTNCARYTNGCNGAY GCNGGNYTNTAYACNTGYGTNGCNACNAAYGGNTTYGGNAGYATGAAYATHAAYTAYACN GTNGTNGTNMGNGAYGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CAYGTNCAYAARGAYGGNGARCAY TGYCAYACNTCNGGNGCNAARTAYGGNTAYATHAARGGNGAYYTNGARTTYTAYAARGCN GARTGYAAYMGNYTNYTNGGNTGYATHGAYGARYTNYTNCARCARATHAAYCCNATHTCN GTNYTNCARGGNGAYAARATHAGYYTNMGNAARGTNTGYMGNYTNGTNAAYGTNCCNGAY AAYAAYAGYACNTCNTCNATGTTYGAYAARTGYACNATHAARGARMGNGARGGNATGATG AARCAYYTNGAYAGYMGNATHMGNGAYAARATGAARMGNGARAAY---TGGGARGARGTN GCNGTNTGYYTNGARAAYAGYTAYGGNGAYGCNGARMGNACNACNTAYGTNMGNGAYATH TGYMGNYTNGCNGARAARGARGAYAAYATHTGYGGNAARTAYAAYATHCARAARCAYGTN GARCAYTTYGTNAAYGAYCARATHGAYCAYYTNCAYTGYACNTGYGTNTCNYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGYTNGGNGARGGNAGYGGNGTNATGGAR AARAARATHATHGGNMGN------CARCCNGCNGCNTCNGCNAAYGGN---ACNAAYAGY YTNGARMGNAARTCNGAYTTYGTNCCNAAYAARMGNGGNMGNGGNMGN---MGNCARAGY TTYTTYCCNACNGGNAARACNTCNGAY---GGNCARGGNCCNMGNCCNAAYCCNATHCAR AARTGGGAYMGNCCNATHGGNGAYMGNMGNCARMGNCARMGNGGNGGNTAYGAYTAYMGN CARMGNGARGARGTNGTNGARAGYGGNGAYATHTTYGAYGTNYTNACNACNGGNTCNMGN AARGGNAAYGCNAAYCAYYTNYTNAAYTTYAARTTYAGYGTNCAYGAYGAYCAYAAYMGN TCNTAYTTYAARTCNMGNMGNTTYGCNGGNTCNGGN------------------------ AARGCNAARMGNTAYAARAARGARCARTTYYTNCARGCNTGYTGYCARTTYATHGTNMGN GAYACNGGNGAYTAYACNGARCARGCNATHAAYTGYGAYACNYTNGTNGAYTGGAGYATG ATHGARYTNGTNMGNAGYTTYTCNAAYGARACNGTNCAYTGYCCNATHTGYYTNCARTAY CCNGTNGCNGGNAARATHACNMGNTGYGGNCAYACNTAYTGYTGGGCNTGYATHYTNCAY TAYYTNAARYTNGGNCARGAYGARGCNMGNAARTGYCCNATHTGYTTYGARACNGTNGAR GTNGAYGARYTNMGNAGYGTNCARTGGATHGAYGTNCCNAGYTTYAAYATHGGNGAYGAR ATHAGYYTNAARYTNATGMGNAARGCNAARGGNAGYGTNYTNGTNTTYCCNAARGARGAR TGGGARGAYMGNAARGGNAARCAYATGAGYATHAARGAYGGNCCNAAYACNAARTAYATG AARYTNYTNGTNGCNTCNYTNCARCARATHCARAGYGARGTNATHGAYAARGARMGNGAY GCNYTNACNGCNCARYTNATHGAYGCNGARGAYTCNGARGTNTGYTTYATHCARATGGCN YTNGAYTGYYTNGCNGCNMGNGARGCNTCNYTNGAYGGNCCNAARAAYACNGTNTAYATH CCNGGNYTNGGNTCNATHGAR---------------GCNMGNAARTCNGAYGAYGTNCCN GTNAGYTCNGCNAAYATHGGNTCNAGYATHGAYTGYACNACNTAYACNGAYGCNTTYGAR GAYGARATH--------------------------------------------------- ------------------------GARGARACNGTNGAR--------------------- ------------------------------YTNGCNGTNGCNGAYACNTCNYTNTCNGTN TGYGAYTCNGAY------------------------------------------------ ------------------MGNCARMGNAAYGAYAGYGARAGYTCNYTNCCNTTYGGNTCN CCNCCNTGYCCNTAYCCNYTNYTNCCNGAYCARGARGTNAAYGARGGNYTNYTNAGYYTN GARGARACNTCNGAYAAYYTNGARYTNCCN---------ACNAGYGCNCCNCCNTCNGAY AARMGNATHCCNATHYTNAAYACNTCNGAYAAYTAYTAYTTYTAYCARGCNACNACNGGN CARCAYATHTAYATGAAYTCNYTNAAYGCNCARTGYYTNGCNAARGARTAYGGNTCNYTN GARGAYAGYCCNAAYGTNGTNAARGCNACNATHGTNGCNATHGARMGNATHTTYATGACN GARGAYGTNMGNAARMGNYTNMGNTAYYTNGAYCAYGTNCCNYTNACNAGYGARGTNCAY GTNGTNGARYTNAAYGTNAARCCNCCNACNGTNAGYAARGARACNYTNAARTTYTTYGAR GCNGCNTTYAAYMGNMGNMGNAARCARMGNCARCARAARGARAARGARGAYAARMGNMGN GCNAARAARYTNGARATHGARCAYAARAARAGYTTYGGNATHTAYCCNGARGTNCAYYTN CCNYTNGAYAAYATHTAYCARTTYCCNGCNCCNYTNTCN--------------------- ---GTNAARCARTGGYTNAARCARTCNTAYAAYATHAAYGTNTCNGARGAYTGGYTNACN ACNTGYATHGARTTYATHCARCARGARACNCARGGNACNGCNCCNGGNYTNGARGARATG AARMGNYTNGTNTTYGAYCARTGGYTNATGTCNGAYYTNTCNGARATHGGNAAYCCNGTN ATHCCNGAYGARGTNTCNGARYTNAGYAARTGYTTYYTNCAYGAYGTNTAYCCNYTNCAR ATHATHTCNGTNGTNGAYGTNGCNACNCCNYTNTTYGGNCARYTNCARAARTTYCARACN AAYGGNYTNGCNATGGAYATGATHACNTTYTCNGAYACNTCNTTYAAYAAYAAYTTYAAY AAY------------------AARTCNTCNMGNATGYTNAARYTNGARYTNTCNGAYGGN CAYMGNTAYYTNCARGCNATHGARTAYACNCCNATHMGNGTNYTNAAYAARGAYYTNCCN TCNGGNACNAARGTNYTNATHAARGGNCCNGTNATGAGYMGNMGNCARATGTTYYTNYTN CARGARGARAAYGTNTGYGTNATGGGNGGNGARGTNGAYGAYYTNATHGTNGTNAAYAAY CCNYTNATGAAYYTNCARGCNGARYTNGARMGNAAYMGN--------------------- ------------------------------------------------------------ ------------------------------------------AARCCNCCNACNGCNCCN ACNAAYATGGTNYTNTTYTAYACNTGGATGATHYTNGTNGTNYTNATHATGGTNATHGCN GTNACNACNTAYCARGCNMGNTGYAARGGN------YTNTGYGGNGGNCARCARTCNAAR GGN---GARGAYMGNAARMGNYTNYTNGAYAAYGARTAYGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AGY GGNTGYACNTCNYTNTCNGGNTGYGTNYTNTAYGCNATHGGNGTNAAYTGYCCNAARGTN AARCARYTNATGYTNMGNGAYTGYGTNACNTTYGTNGARGARAAYTTYYTNTCNTTYYTN TTYACNGARCAY------TCNYTNGARTAYYTNGAYATHTCNGGNTGYTGGAAYATGGGN GAYGAYGTNYTNATHAARYTNGTNCARAARTGYTGYAAYYTNAARCAYYTNYTNYTNMGN AAYYTNTTYGGNYTNACNGAYMGNGCNGTNTGYGCNATHGCNCAYTCNTGYCCNGARYTN ATHAGYYTNAGYYTNGTNGGNTGYTGGMGNGTNACNAAYGAYTCNATHAARYTNATHTCN GCNTAYTGYTCNAARYTNAARYTNYTNCAYGTNAARGARTGYMGNGAYGTNACNGARGAR AGYYTNGGNCCNYTNMGNAARMGNCARGTNGCNGTNGAYAARGCNGCNCCNCCN------ ------------------------------------------------------GAYAAR GTNGTNYTNTAYAGYTAYTTYMGNAGYTCNGCNAGYTGGMGNGTNMGNATHGGNYTNGCN YTNAARAAYATHACNTAYGARTAYGARCCNGTNCAYYTNGTNAARGGNCARCARAGYACN GAYGARTAYAARAARYTNAAYCCNATGGGNTAYATHCCNACNYTNAARATHAAYGGNYTN GTNYTNAAYCARTCNYTNCCNATHYTNGARTAYYTNGARGARATHAARCCNGARCCNGCN YTNYTNCCNAARGAYGCNGCNGGNAARGCNCARGTNMGNGCNATHGCNGARGTNATHAAY AGYGGNATGCARCCNYTNCARAAYYTNAARGTNYTNAARAARGTNGGNGAYACNAARATG GARTGGGCNAAYCAYTTYYTNACNGARGGNTTYCARGCNYTNGARGCNATHYTNCARAAY ACNGCNGGNTCNTGYTGYTAYGGNGAYCARGTNACNYTNGCNGAYATHTGYYTNGTNCCN CARGTNGCNAGYGCN---CCNMGNTTYAAYGTNGAYATGAGYCARTTYCCNACNGTNGAR AARGTNAAYAARTAYYTNGTNGARYTNCCNGCNTTYAARGCNGCNGAYTCNMGNMGNCAR CCNGAYACNCCNGARGAYATGMGNATHGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATGCAYGCNCCNGGNTCNCAYGCNGCNCAYTGYYTNCCN GTNGCNGGNYTNMGNCCNCCNGTNGARGCNGAYGTNTAYMGNCAYAAYMGNGTNGTNCCN YTNTTYACNCCNGAYCCNTGYATHGGNCCNAGYACNGGNCARGTNATHTGYCCNCCNGAY TGYGGNCARCARAARMGNAAYGAYYTNATGGARCCNGCNGGNATGAARACNCCNATHGAR TGGCARTTYCARTTYTAYGARCCNMGNCCNTCNAARCCNGARCCNAARGCNGCNTGYAGY TGYCCNGTNTTYGCNAAYMGNCARCCNTGYACNTCNYTNGGNCCNATHACNGAYMGNYTN AAYTGYCCNTCNATHAAYATGGCNGAYAARYTNTCNACNMGNGTNATHCARGTNACNAAY ATHGCNCCNAGYTGYACNAARGAYCARYTNMGNACNYTNTTYGGNTAYYTNGGNMGNATH MGNGAYYTNGCNATGTAYCCNCCNGARGGNGTNGAYAGYTCNGGNGCNTCN---MGNGTN GCNTAYGTNGARTTYGAYGAYTCNYTNACNACNGGNGTNGCNYTNCAYYTNAGYAGYACN GTNTTYATHGAYMGNGCNATHYTNGTNGTNCCNGTNATHGAYGGNAARATHCCNGAYGAR AAYTCNGCNYTNACNYTNACNCCNTCNGCNGTNGCNGGNATGYTNCCNGGNCARCCNACN TGGCCNGCNAAYGTNGTNTCNCARGTNACNGGNYTNGGNGCNAAYCARGTNATHATGACN AAYGAYCCNMGNYTNACNTCNYTNGGNYTNCCNCARTAYCCNCCNYTNCCNGCNACNACN GAYCCNAGYAARATHGARGARATHMGNMGNACNGTNTAYGTNTCNGARYTNGAYGCNAAR GTNACNCCNGARATGYTNYTNTCNTTYTTYTCNCARACNGGNGARATHAARTAYATHMGN ATGGCNGGNGAYGARAAYGCNTCNACNMGNAGYGCNTAYATHGARTTYACNGAYCARMGN TGYATHGCNCARGCNYTNAGYTAYAAYAAYATHGTNTTYCARGGNMGNACNGTNAGYGTN AARCAYGCNACNACNAGYATHGTNAARCCNACNCCNAARTCNGARGCNTCNCARMGNGAR ATHGAYGAYGCNATGAARAARGTNAARGARGCNTCNAARYTNATHTCNGCNGCNGCNAAY AGYGARMGNGARGGNTCNAARTCNCCNACNMGNAAR------MGNTCNAARTCNMGNGGN MGNAGYMGNTCNCAYTCNAARTCNMGNAARTCNMGNTCNMGNTCNMGN---GGNMGNMGN MGNMGNAGYAGYTCNAARTCNMGNMGNMGNTCNMGNTCNMGNMGNMGNTCNCCNMGNMGN TCNMGNACNCCNGTNMGNMGNMGNMGNTCNMGNTCNMGNGGNMGNGARCCNCCNTCNGCN CCNCCNYTN------------------TCNMGNMGNMGNTCNMGNACNMGNTCNCCNGTN MGNAARMGNMGNTCNMGNAGYMGNTCNAARTCNMGNGCNMGNMGNTCNMGNACNCCNCCN AARTCNTAYAGYMGNGGNMGNMGNTCNMGNTCNMGNGGNMGNAARAGYMGNTCNMGNGAY MGNAARGARMGNMGNGARAARAARAARAGYMGNTCNATGTCNCCNCCNACNYTNGTNMGN GARGGNTCNGTNYTNGCNATHGARGAYGGNGAYAARTCNCCNGTNAARGGNAAYGGNMGN TCNCCNAGYCCNTCNAARGTNAARAARMGNAGYCCNTCNCCNAARMGNMGNAGYMGNTCN AARTCNCCNAGYMGNMGNAARAARMGNCAY---------MGNTCNMGNTCNGCNTCNAAR MGNTCNMGNTCNMGNAGYGGNTCNMGNCAYMGNACNMGNMGNGAYMGNAARMGNAGYMGN AGYMGNGAYMGNAARCAYGARAGYAGYMGNAARAARACNAGYMGNGAYAARGAYGAYMGN AARAARGAY------------TCNAARATHAARMGNGAYTAYGAYGARGARGARAARGGN TTYGCNAGYGAYMGNAGYGARGARAARGARAAYAGYGARGGNCARAARGCNYTNGAYTCN CCNAAYAGYGAYCARYTNCCNCCNATHYTNGARAARGAYACNGAYATHCARCCNGTNGAY ATGGAYATGAGYGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYGAYTTYGARATHGAYGARCAYTCNGTNTCNACNCARMGN CCNGAYGGNCARGTNGARACNGTNACNACNGTNACNGCNACNATHYTNGCNGGNGTNAAR GARGARGARGARGAYGAYGAYAAYGAYGGNMGNTCNCARTAYGAYAAYGARGAR------ ---ACNAAYAARGAYGARATHTAYGGNAARATHGCNCARAARYTNATHGARATGGCNGAY ACNTAYAGYACNAAYGTNTCNGAYACNGARACNGCNGCNGCNGARGAY---------GCN CCNYTNACNGAYYTNGARAARGARATHATHGCNTGYYTNMGNTCNAGYGGNGAYMGNTAY GCNAARAARATGGARGAYCARYTNGAYGCNTTYAARACNGCNGTNGCNGARGAYGCNTAY GGNMGNTTYAARAGYACNGTNGARAAYTCNATGGGNCAYGARYTNAGYTGGAAYACNYTN GCNYTNYTNTTYTAYGCNACNAARGGNGTNGTNTCNGCNGTNGGNAARGGNTCNCARGTN GCNACNCARGCNAARGARTTYACNYTNAARTAYATHAGYGAYACNTTYGTNTCNTGGATH ATGGARCARGGNGGNTTYGAYAGYATGYTNAGYGCNAGYGARTCNGAYCCNGARYTNGAY TTYGAYGGNGAYYTNCARAAYMGNGGNMGNYTNAARGGNTCNGTNCCNYTNAGYTCNATH AARGTNGTNMGNGARGTNGAYGAYAARAGYYTNGARGAYAARTGYAAYGTNTTYCARATH GTNTAYGARGAYAARAARGAYTTYYTNATHYTNTAYATGATHGCNAARACNAAYAAYGAR MGNCARGCNTGGYTNACNGCNYTNGCNGARGARGCNYTNAAYTGYGGNGCNCARTTYTTY GCNAARTTYCAYCCNGGNGTNTGGACNAARAARYTNGGNTAYTAYAAYTGYTGYGAYCAR TGYGAYMGNAAYGCNATHGGNTGYAARAGYGAYCAYYTNGTNCARMGNATHCCNYTNCCN CCNGTNCCNTCNCCNMGNCCNGAYCCNGGNAAYMGNYTNGARTAYATHGCNYTNTTYGAY TTYGAYCCNCCNGAYGARGGNGAYYTNGARYTNATHCARGGNGARAARTAYATHATHYTN GAYAARAGYGCNGARAAYTGGTGGTAYGCNGARAAYMGNGARGGNAARAARGGNTAYATH CCNTCNAAYTAYGTNAARATHAAYGCNGGNYTNGARCARTAYGARTGGTAYTAYAARGAY TGYTCNMGNGARMGNAGYACNCARATHYTNYTNAARAGYTGYAARGAYGGNTGYTTYATG GTNMGNGAYTCNGTNAGYCAYCCNGGNACNTAYTCNYTNTCNATHTTYACNACNGARAAY AAYGGNAAYGTNMGNCAYTAYAARATHMGNTGYAAYGAYCARGGNAARTAYTAYGTNTCN GCNACNCAYACNTTYGARACNATHCCNGARYTNATHCAYTAYCAYAARCAYAAYAARGTN GARYTNGARCARAARCARGGNAARYTNYTNGAYTTYGCNNNNCARGTNTGYTGYGGNATG GARTAYYTNAAYAAYMGNCARATHATHCAYMGNGAYYTNGCNGCNMGNAAYTGYYTNGTN GGNAARGAYGARYTNGTNAARGTNGGNGAYTTYGGNYTNGCNMGNGARGTNYTNATGGAY TTYGARTAYCAYATGTCNGARMGNTCNAARTTYCCNTTYAARTGGTCNCCNCCNGARGTN YTNYTNTTYMGNCARTAYACNAAYAARTCNGAYGTNTGGGCNTAYGGNATHYTNYTNTGG GARATHTAYACNTTYGGNGAYATGCCNTAYCARGGNTTYACNAAYCCNGARGTNATHAAR TTYGTNGCNACNGARGAYAARMGNYTNAGYAARCCNAARGCNGCNCCNTCNCCNYTNTAY GARGTNATGYTNMGNTGYTGGGAYAARTAYCAYCARGAYMGNCCNAAYTTYACNGCNATH AARMGNAARYTNGARATGYTNAGYGGNAARGGNGAYTAYATHCCN--------------- ------------------------GTNGGNCAYTGYCAYYTNTGYYTNYTNAGYCCNCCN CARMGNGGNTCNATGATGGGNATHAAYAARCCNGGNGCNTCNGAYTGYATHYTNYTNAAR GGNCCNTGYGGNGGNMGNGCNAARTCNGCNACNGTNATHCARATHGCNGGNGGNTCNACN TTYACNGTNACNTTYCARAARAAYYTNGAYCAYTTYATHAGYACNTCNCCNGGNAARTTY GTNGTNTCNATHGGNCCNAAYGCNAAYTCNATGGTNCARYTNGCNTCNATHGCNGAYACN GCNACNCCNTCNYTNACNYTNTAYTCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GCNAGYYTNAAYTAYGGNTCNCCNAAYCCNGCNAAR TCNMGNGCNGGNCARGTNCCNTGGGTNMGNYTNAARMGNMGNGARTCNYTNGGNYTNGCN GAYTAYATHAGYGGNMGNACNCCNCARAGYCCNAAYACNGTNAARYTNGCNCCNGTNGAR CCNTCNGGNYTNCCNGCNGCNCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARATHTCNCAY ATGATHGCNTTYATHGAYCARGARGCNTCNGARAARGTNGARGARATHGAYYTNAARGCN GARGARGARTTYAAYATHGARAARGGNMGNYTNGTNCARCARTCNMGNGTNCARATHATH GAYTTYTAYGAYAARAARATHAARAAYGTNGARYTNCARAARAARATHCARAGYTCNAAY ATGCARAAYAAYGCNMGNYTNGARATHYTNMGNAARAARGARGAYTAYGTNAARGARATH YTNGAYGARGCNMGNGARCARYTNMGNMGNAGYGCNAARGARAAYCCNGARGARTAYAAR CAYYTNYTNYTNMGNYTNATHYTNCARGCNYTNGCNMGNYTNGTNGARCARAARGTNACN ATHMGNTGYAARMGNGARGAYATHCARATGATHAARAAYGCNATHCCNAGYYTNACNAAR GARTAYAARGARYTNATGAARGGNAARTAYAGYGTNGARYTNGTNGTNGAYGARGAYAAR TTYYTNTCNCCNGAYATHACNGGNGGNATHGARYTNCAYGCNATGAGYGGNAARATHGTN GTNGTNAAYACNYTNGAYGARMGN---AGYGARTCNGTNACNGGNGCNTAYGTNYTNTGY YTNATHCAYCARMGNMGNGTNCAYCARTAYMGNATHYTNCCNGAYAARGAYGGNAARATH TCNGTNCARTCNGARGGNGAYATGCARCCNCCNTCNTAYGCNGAYAGYYTNATHACNTCN TAYATHAAYMGNGGNGARAARAAYGGNYTNGTNTGYGCNYTNMGNMGNCCNATHGCNCCN GARGGNGCNGARATHYTNCARMGNGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGCNGARAGYGAYCARCARTAYACNATHTAYGAY---GGNAAYCARCCNYTNACNYTN GCNGTNGGNAAYGTNAAYCARGGNACNGARGAYGCNCARGCNGTNCARAGYATHCARTAY ATHTCNCARGAYGGNATHCCNGTNACNCARYTNGAYTCNACNGAYGTNATHCARGTNGCN CARGCNGCNGAYGGNACNTTYCARCARGCNACNCCNGCNTTYCARAAYATHCARGCNAGY GTNCARCCNCARGTNATGGCNAAYACNGGNTCNGTNCCNYTNGTNGCNGCNACNTCNCAR GGNGGNAAYATHYTN---CARTCNAGYGTNGTNGCNAAYGTNGCNCARCARGCNCCNCAR YTNTCNCARCARACNTCNCARACNTCNCARGCNGCNGGNCCNTCNMGNYTNAAYGTNACN AGYAAYGTNGGNATHCCNCARATGYTNTTYYTNAAYCARGTNACNATHAAYGGNCARACN TCNTTYGTNYTNGTNGAYGTNGAYAAYAARCCNATHCARYTNCCNCARGGNATHCARGTN ATHAAYYTNCCNCAYCARCARYTNTCNGGNCARTCNGTNCARATGCCNGGNGCNGAYACN GGNGAYGARCCNYTNTAYGTNAAYGCNAARCARTAYCAYMGNATHYTNAARMGNMGNCAR GCNMGNGCNAARYTNGARTCNGARGGNAARATHCCNAARGARMGNCARAARTAYYTNTAY GARTCNMGNCAYMGNCAYGCNYTNAAYMGNGCNMGNGGNTCNGGNGGNATHTTYGTNGGN CAR------TCNYTNGAYGTNGTNYTNATHYTNGGNAARAAYAARATHCCNGTNACNYTN MGNCCNTCNGCNAARGCNTTYGGNGARGARTGYYTNTCNGTNAAYCAYYTNTGYYTNGCN GTNGARGARCAYGCNAAYATHAARCCNAAYGCNCARAARYTNATHTAYMGNGGNMGNACN YTNTTYAARACNTAYAAYCCNGAYGAYGARGCNYTNMGNAARAGYYTNTCNTCNYTNGGN GTNAARAAYGGNGAYMGNATHATGGTNTTYGGNAARATGTCN------CARCCNAAYAAY GARGARGARAARGGNAGYAAYGAYGCNCARYTNATGAARGTNYTNGAYCARCAYCARGCN MGNATHGAYCARATHTGYMGNGTNTGYGTNGAYATGGTNAAYAARATHGGNGAYGARTCN TCNACNGTNGARGARATGAARAARCAYAARAARTTYTTYYTNGGNCARTCNGARTAYTCN ATGCARGARYTNACNGGNYTNGAYGCNACNCCNGGNGAYYTNTCNCARMGNCARGARTAY AARACNMGNMGNAARGCNYTNGTNAAYAARYTNYTNGARAAYATHTCNYTNTGYGAYAAY CARGTNTCNAAR------------------------------------------------ ------------------------------------------------------ATGAAY AARCCNGTNGARGARTGGCCNATHGTNAAYGGNYTNATHTCNTTYTTYTCNCAYGGNTTY CCNYTNGAYAARGCNATHGCNTAYAARAAYYTNMGNCARCCNTTYATHGTNAAYGAYYTN GARATGCARTAYGTNYTNCARGAYMGNMGNCARGTNTAYGCNATGATGGARGCNAAYAAY ATHCCNCAYCCNMGNTAYGCNGTNYTNGAYMGNGARAAYGAYCCNAAYTGYCARGTNATH GARACNGARGAYTCNATHGARTTYAAYGGNAAYGTNTTYATGAARCCNTTYGTNGARAAR CCNGTNGAYGCNGARGAYCAYAAYATHTAYATHTAYTTYCCNCARGCNGCNGGNGGNGGN AGYACNMGNYTNTTYMGNAARATHAARGAYMGNAGYAGYGTNTAYYTNMGNTTYTGYMGN GTNMGNTCNAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARGCNTTYAARATGGGNAAR------ TCNTCNTCNAGYTCNAGYTCNAGYAGYAGYGARTCNTCNGAYGAYGARTGGMGNCAYATG TCNAARAARGAYAARAARATGMGNAARAARTGGAARAARCARATGAARMGNGGNATGGTN CCNCAYGGNACNYTNCCNCCNTGGCARGGNGGNCCNATGTGGGCNCCNACNAGYAARGGN ---------------CAYAARAARGGNCAYAARAARGGNAARGGNGGNTAYCCNTCNATG GGNTAYCCNGGNCARCCNGGNTAYCCNCARCARAAYCCNGCNTAYCCNCCNGGNGGNTAY CCN---------GGNGTNCCNCCNCARCAYGGNGCNTAYCCNGGNGCNCCNCCN------ ---CCNCAYGGNGCNTAYCCN------GGNGTNCCNCCNCARGGNGGNTAYCCNCCNGGN GCNGCNCCNCCNGGNGGNTAYCCNGCNGGNTCNTAYCCNCCN------------------ ------CCNCCNGCNGCNCARTAY---GCNGCNCCNGGNGCNGCNTAYGGNTCNCAYGGN GCNCCNTCNGGNCCNTTYCARGCN------------------------------------ ------------GTNGARYTNAGYGARACNAAYGAYYTNATGAARGARATHGARAGYGAY MGNGTNAAYYTNTCNACNTTYYTNGARAARCARGGNCARCARYTNGARGGNYTNGAYAAR GARMGNCARAARGTNYTNGARGARYTNGARTCNGCNGCNGCNGARMGNACNACNYTNAGY CARGARAARATHACNYTNTCNAARMGNGCNGARGARYTNCARAARTCNYTNCARGAYATH GARGAYAARACNAARGCNATHCARGAYGARAARTCNACNGCNGARGTNMGNYTNAARGAY AAYYTNGARMGNYTNGAYCARYTNGARTTYGARAARTCNATGATHTCNGARCAYGCNTCN GARYTNGARGGNACNATHCAYGAYYTNGTNTCNCARAARGARYTNACNGARAARGARYTN AARGARGARATHMGNGCNMGNATHTCNGCNGARGARMGNYTNAARGARGCNGARAAYTCN YTNGAYTCNYTNGAYCAYGCNGTNAARACNCARTCNCAYMGNATHGARGARGGNGCNAAR GARGARATGACNGTNAGYGTNMGNAARYTNAARCAYTTYTTYGARGAYYTNGCNGARGAR GCNAARATHTCNTCNGAYAARCCNATHGTNATHMGNAAYGGNYTNATGGCNMGNAARACN YTNGCNMGNMGNGCNAARACNATHMGNTAYGARAAYMGNMGNMGNTCNTCNACNTTYGTN GGNGGNTTYTTYGGNAGYATHATHTGGGGNMGNYTNGCNGAYMGNAARGGNMGNAARATH GGNATGACNYTNCCNYTNGTNYTNATGTCNYTNYTNAAYACNGCNTTYGGNYTNACNYTN GAYATHTGGATGGCNATGTGYYTNMGNYTNATGACNGGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARTCNTGYCCNGCNCCNTTYCARMGNACN MGNGAYTGYGARAARGTNMGNGARGGNATHAGYCCNYTNAGYMGNCARGGNYTNGTNTGY ATHAARAARGAYAAYTGYTAYAAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AAYACNAGYTAYYTNGGN--------------- ------YTNAARACNGGNAARGCNGGNTGYGCNACNCCNAARAARGAYGCNAAYGGNGCN CAYTTYCAYMGNCCNCCNAAYTTYACNTAYGCNAARGAYACNCCNCCNTTYYTNAARAAR AARGGNACNGGNATGTCNGCNYTNACNTCNGTNACNMGNGTNGTNAARGTNMGNMGNAGY TCNTCNCCNGGNGAYATGMGNAAYCARGARGCNGTNMGNYTNAGYATGTTYCCNGGNGCN AARCCNMGNCARCCNGAYGARCCNGARACNATHGARMGNGAYGAYTGGCCNGGNCCNGCN TCNCCNGCNGCNATHYTNCCNGARATHYTNMGNAARMGNMGNAARAGYMGNGGNGARAAR GAYGARGAYGARGAYGARGARGARGTNAARGARGAYCCNMGNATHCARAARGARYTNCAR GARATGTCNAARATHAARGAYAARAGYGCNATHGGNTCNGCNATHTAYAARCARYTNGAR ACNYTNAARGCNAARCCNCAYCARCCNYTNGAYCCNTGGAARGCNTCNMGNGTNCCNAGY GCNAARTTYGARCCNMGNTAYMGNACNMGNTTYCARTCNCCNATGTTYGCNTCNCCNTCN MGNTTYYTNGAYMGNCCNMGNTAYGCNTGGGAYGAYATHGAYATHMGNACNTAYMGNTCN GCNTCNACNYTNGCNAAYYTNCCNACNCCNAARCCNGGNTAYGGNCCNTCNTAYATGCCN CCNMGNGCNGCNACNYTNCCNYTNTCNGGNGCNTAYGGNGCNMGNGAYGAYTTYMGNTTY TAYGARTTYGAYGARTCNGARGAYMGNGCNAAYACNAAYYTNTCNTCNTCNACNYTNACN GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYAAY YTNCAYTTYATHTTYAGYACNAARGARYTNCCNACNGTNYTNATHGCNMGNACNTCNAAR YTNGAYTCNGAYATHCARTTYAAYTGGGAYATHATHYTNAAYGARACNTCNYTNGARAAR GGNATHACNTTYTCNAAYAAYATHAARCCNGAYTAYAARTTYGGNATHTGYTTYACNCAR YTNATHGARTAYGAYGAYCARCAYGAYGAYGCNAAYYTNAAYGAYTGYACNAARCAYGAY ATGATGTGYCARYTNMGNTCNTTYAARACNTTYTCNTGGYTNCCNYTNAAYGARACNACN GTNGARGARACNYTNGTNTTYAAYACNTCNGAYGAYAARATGACNCCNTCNYTNTCNYTN AAYGGNACNYTNTCNTTYTCNTTYAAYATHCCNGGNAARGAYGGNMGNGTNTCNGCNCAR CCNGCNCARAARTAYACNGGNAAYGARACNYTNTTYGARTTYATGYTNGAYAAYTAYACN CCNGCNTAYAAYCARTCNMGNTTYGCNYTNGGNGCNGTNGTNATHAGYCARGAYAARMGN TCNAARATGAGYGTNGAYACNATHAARACNATHGAYGAYGARTAYTCNCCNGGNGTNTTY CARYTNACNAAYTGGYTNACNAAYTCNATHGAYAAYTCNAARAGYGGNTTYATHCARTGG AARCCNGTNGCNTAYTTYGGNAARACNMGNGGNMGNCARACNTCNACNAARGTNGAYCAR TAYGGNYTNAARGAYYTNGAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNGTNYTNGCNGAYTTYYTNGTNTCNTGYGGNYTNACNYTNYTN TGGATHATHGCNTCNTCNGCNTGGGCNTCNGGNYTNAGYGAYGTNAARYTNTAYACNGAY CCNTAYGAYGGNGARGTNTTY---CARAAYGTNAARGARTGY---AAYCCNAARGGNGCN TGYTTYACNTCNAARGARGGNAAYTTYGCNAGYYTNAAYGTNTCNATHATHTTYGGNTTY YTNAAYTTYATGGTNTGGGTNGGNAAYYTNTGGTTYYTNTAYAARGARACNCCNTGGTTY AARGTNCARGCNAARCCNCCNGCNCARCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TGGTCNCARAAYAAYGARACNGTNTTYAAYCARYTNCAR GARATHGGNTGGAAYAARGTNYTNAAYYTNTCNGARAAYTTYTCNTGYGTNGARATHTGY TGYACNGAYMGNAGYCARMGNCAYCAYMGNYTNAARGTNCARTTYGARATGCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARAAYTCN GGNYTNGAYGCNGCNAARMGNMGNGCNYTNCCNYTNTGGYTNMGNGARGGNYTNGARAAR ATGGARMGNGAYAARCARAARCARYTNGARAARGARCARYTNAARYTNCARAARGARATG TAYAARATHCARGARATHGAYGAYAARGTNAARGARGAYGARGARGGNGAYGAY------ ---GGNCARCCNMGNATHCCNMGNAARAGYMGNTTYGAYTCNGAYGAYGARGAR------ ---GAYGARAARGCN------GAYGGNGAYGGNGTN---AGYGAYGARGARAARGCNCCN AAR---------------CCNACNAARCCNGARACNTCNGARAARGARTCNCCNGTNMGN AARAGYCCNTCNCCNACNGARTTYATGACNGARGARGARAARGARATHGCNATGATGATG AARGTNAARMGNYTNYTNACNGARACNYTNYTNGAYGTNACNGAYCARGARATGAARAGY ATHGCNTCNGARGTNTAYCARAARGARAARAARAARGCNCARAARGCNCCNGCNAARCAR YTNGCNAARTCNTCNGCNYTNGCNTCNYTNACNAGYYTNGGNYTNGGNTAYGGNTCN--- ---------------GGNAGYGAYAGYGAYCARGARGARGARGAYTCNGAYTCNGAYYTN GARGARMGNATHMGNCARAARAARGCNGARTTYGCNAARMGNMGNAARATHTTYAGYGAR TCNGARGGNGARGAYGAYAARCCN---------YTNTCNACNAARAARMGNAGYGARAAR GARAAYGAYTCNAGYAARGGNGGNAARMGNAGYAAYAARGAYATHGARAARMGNCAYACN GGNMGNCARGAYGARAARGARGAYAARAGYAARMGNGARAGYAARGARGARAARATHATH AARAARGARYTNGARACNAAYTCNAARACNMGN------------------MGNGAYATH AARATHGARATGAARAGYGAR--------------------------------------- ------GTNAARAARGARAGYGGNGAYAARAAYTCNMGNYTNTCNAAYAAYYTNACNAGY MGNGTNAAYTCNYTNAAYGARAARAAYAARTCNAARGTNGTNACNCARGAR--------- ------------------------------------GARAGYAAYAGYAAYAGYAGYAGY GARACNAGYGAYAGYAGYAGYAGYGGNAGYGAYTCNTCNAGYTCNGAYTCNGARGAYAGY AGYAGYGGNAGYAGYGAYAGYGARGGNGARAAYTCNTCNTCNTCNTCNTCNTCNGCNTCN ATGCCNAGYAGYAAY--------------------------------------------- ------------AARTTYATHTCNAARTCNGGNGCNAARAAYACNCAYTTYGTNGARAAR MGNGAYAARCARATHTCNCARGARCCNAARCARGTNGARAARGTNGTNAARCAR------ ---CAYAGYGAYGCNAARGAY------------------------------GARGAYGGN GCNGTNAARGAYTCNMGNCAYAARAARTTYCARMGNGAYGAYAARAAYGAYAARACNYTN CARAARGARTCNGCNGTNAARGTNAGYAARGGNAAYGARAARTCNCAYGARAARGARGAR GCNAAY------------------GARMGNGGNGAYGARTCNAAR---AARAARAARGAR AARMGNMGNTCNATHGARGARGARTCNGTNATGAARYTNGARYTNAARAAYAARTCNAAY AGYGARGAYAAYGTNAARCAYAARGCNCARAARAGYGAYMGNGARMGNGCNATGAGYMGN TCNCCNAGYMGNAARAAYYTNAGYMGNAGYMGNAGYACNTCNCCNGARGCNMGNACNAAR AARMGNAGYAGYMGNAGYGAYTCNMGNGAYCAYYTNGGNAGYMGNMGNMGNMGNAGYAAY ------ACNMGNAGYMGNAGYAAYTCNGTNGGNAARTAYAARCARACNAGYMGNMGNAGY ------------------MGNAGYAAYTCNATGGARTAYTAYMGNAARAARMGNGGNMGN AGYMGNAGYAAYTCNGARAARGAYAGYTTYMGNTCNAARMGNTCNMGNMGNGAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNGARCARYTNYTNCAY AARCARCCNAAYCARGARATHYTNGAYCAYGARMGNAARMGNAARGTNGARYTNAARTGY ATGGARATGCARGARYTNATGGARGARCARGGNTAYACNAGYAARGARGTNACNGAYAAR GTNAAYATGTTYMGNAARATGYTNATGGCNAARGARGGNGTNTCNGAY---ACNCCNATH GARAARGAYGARCAYGGNMGNCCNATHGCNAARGARACNCAYCARYTNGCNGARGCNAAY CARGCNAARAAYGAYAARYTNAARGARGCNTTYGGNYTNACNGAYTAYGTNGARGGNAGY GCNTTYGAYCCNGAYMGNAARGCNAARGARGARCARGCNAARGCNYTNGCNYTNGCNCAR AARAARTAYAGYATHGTNAAYAGYTCNGARGARGARGARCAYAAR---GARAGYTCNCCN TCNCCNAARAARAARAARAARAARTCNMGNCAYGARGAYGCNTCNTCNCCNGARMGNAGY AARGARAARMGNAARAARAGYMGNAARCAYAGYAARMGNGAYMGNGARGTNYTNGCNYTN CARAAYACNAAYAARCARYTNMGNAAYGARATGCARGCNGARCARGAYAAYGCNYTNCAR YTNMGNAARAARATHAAYACNGTNGARAARCARAARYTNGARGCNGARACNMGNGCNAAY GGNGARATHTCNGCNYTNGARACNCARGTNGCNAARYTNMGNTCNCARGTNGARAARGGN GARGCNACNMGNCAYAAYYTNGARTTYGARYTNACNGTNAGYCARMGNGARTCNAAYAAR YTNCARCARATGACNTCNGARAARGARTCNGTNTTYAARCARACNACNGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ACNACNACNGCN ATGAARGAYCCNTTYGCNGAYGCNGAYATHTAYCAYGAYTAYCAYACNTAYTAYAAYTCN ACNGCNATGAARGARACNGTNGCNACNCAYTAY---GTNGAYYTNTCNTCNGGNTCNMGN CAYGARGTNYTNTCNAGYAGYCAYMGNGTNGCNGCNGTNATHAARYTNAARTTYAARTTY CCNTTYTAYGGNCAYCCNATHACNAAYATHACNGTNGCNACNGGNGGNTTYYTNTAYATG AGYCCNTTYYTNCAYCARTGGYTNACNGCNACNCARTAYATHGCNCCNYTNATGGCNAAY TTYGAYCCNTCNYTNAGYAARAGYTCNCAYATHTAYTAYYTNAAYGARGAYGARAARTTY ACNGTNGARTGGMGNGARGTNATHYTNMGNGAYCARCCNAAYTAYGGNAAYTTYACNTTY CARGCNTCNYTNCAYATGAAYGGNAGYATHAGYTTYGGNTAYAARAAYGTNCCNATHGAY GTNAAYAARATHTCNGAYGAYAAYCAYCCNGTNAARATHGGNYTNTCNGAYGCNTAYTAY AAYGAYACNTAYYTNCCNAAYTGGGGNATHMGNMGNMGNACNATHTTYGARTAYCAYCAR GTNGCNYTNMGNAARAGYYTNGCNAARACNGGNGCNGTNATHYTNGTNAAYCCNYTNCCN ACNTGYAAYGTNYTNGARGAYTGYGAYTCNTGYACNMGNCAYACNGGNGTNAAYTTYGAY TGYATGTGGTGYAAYACNATHGGNMGNTGYTCNGAYGGNYTNGAYTGGTTYMGNCARCAY TGGGAYAARTAYGGNTGYAARGCNGTNAGYATHGARGAYGARGARAARTGYACNTCNYTN CCNCCNAARACNCAYCCNCARACNACNCCNGCNACNACNTCNACNAARACNATGACNAAY TGYGCNGGNGGNAARTGYGGNAARAGYGCNAGYGTNCCNGTNGCNGTNATHGTNGTNYTN ATHYTNGTN---YTNYTNGGNYTNGTNGCNGGNGTNGGNGGNTGGACNTTYTAYGCNTAY ACNCAYCCNACNTCNMGNTCNGGNATGTGGYTNATGGARCAYMGNCCNAGYCARATHAAR GCNAARATHAARTTYTGGAARAGYAGYTCNGAYAGYGCNGCNAARTAYMGNACNGARACN GAYGCNYTNGARACNGTNMGNYTNAAYTCNMGNYTNTCNGARGARYTNGGNTCNGCNMGN AARGARATHGARTTYYTNAARGGNMGNYTNAARGARYTNGARATGAARCARYTNGCNMGN GARTCNTTYTTYAAYCARCAYCARTGYCARCAYMGNAAYAAYAARAAYGGNYTNTCNTCN AARTCNTAYMGNMGNGTNTCNGCNCCNCCNGGNAGYYTNYTNTAYGCNGARCCNYTNTAY GGNTGYAARTGYTCNGCNTGYGARGARGCNATGAGYAGYGAYATHAAYTCNGCNYTNAGY GCNTCNYTNAAYGARAARYTNCARAARTTYCCNATHAGYCCNACNGTNYTNGTNCARYTN GGNGAYCAYGTNGTNACNAARGGNGAYATGACNGGNMGNATHMGNTAYATHGGNCAYYTN GAYAARATHGGNCARCCNAAYATGGTNTAYGTNGGNYTNGARYTNGAYGCNCCNGTNGGN CAYCAYGAYGGNTTYTTYAAYAAYAARMGNTAYTTYTTYTGYCARAARGAYCAYGGNATG TTYGTNCCNYTNCAYGAYACNYTNTGYAARGTNAAYGTNAARAAYAAYAGY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNMGNAGYCAYATHCARCARGARGARGARGTNAARAARGTNGTNMGNAAY TTYGTNGAYTTYAAYTTYCCNYTNGAYAAYGCNTTYGGNYTNATGTAYGCNTGYGTNGGN MGNGGNAGYAAYYTNTAY---AARYTNAAYGTNGARTCNGARACNTTYAARAGYTTYTTY CCNAAYGTNCCNYTNATHGGNTTYTTYGGNAAYGGNGARATHGGNTGYACNTTY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GTNGCNTCNTGGYTN TCNCARATHTTYGGNAAYGARCARATHCCNGAYTTYGARAARAAYTCNCARACNATHGAR YTNYTNCAYCARYTNTTYACNATHTGYCAYTGGAAYGARAGYAAYGCNCARYTNTAYYTN GARGAYYTNAARMGNAARTCNGARGARTAYGAYACNGAYGCNYTNMGNGTNGGNGCNATH ATGGGNMGNYTNACNYTNGGNGARCAYAGYYTNTCNTCNACNGCNTCNGCNCAYAAYCAR GCNYTNGCNCARACNGGNGCNYTNYTNTGYGTNAARAAYGCNTCNGAYGCNAGYTTYATG YTNTCNYTNMGNGARYTNAARTCNGAYYTNAAYGARGTNGCNGAYAARYTNCARGTNGAR TGYAARGAYATHCARAARYTNTCNAARAARACNCARGCNATHYTNATHAARCAYAAYTCN YTNGAYAARGCNYTNGARGARGTNGARAARMGNTCNGTNMGNGARGTNGCNCARYTNAAR AARGARAARAARGARACNGARATGYTNAARAARACNACNGARGCNGAYGARCAYAARATH TCNAARYTNAARACNGARYTNGCNAARACNGGNYTNAGYCARTCNTAYTTYCAYGAYAAY YTNGTNAARAARAARGARAARYTNGAYGGNATHCARGAYGARYTNGTNCCNYTNAARGAY AARYTNGARTCNTAYGCNACNYTNCCNCCNAAYGCNGTNGARGCNAARGTNAARATHGAR CARYTNAARATGGARYTNGCNGARYTNAARGCNCARATGTCNGARTGYGTNGGNGTN--- ------------------------------------------YTNYTNYTNTCNYTNTGY GCNTCNACNGARGCNTTYYTNGTNTTYTCNGCNGGNGTNTGYCCNCARGTNGARGTNAAR CARAAYTTYAAYATHACNGCNTAYCARGGNMGNTGGTTYAGYTAYGARAAYTTYGAYGCN CCNTAYCARTTYGGNATGTCNTGYGTNACNGCNAAYTAYMGNYTNYTNCCNGGNGGNAGY ATHGARGTNATHAAYGARGGNTAYMGNGARATHMGNGTNTTYGGNYTNTCNYTNTAYMGN MGNGAYGTNAARGCNGTNGGNGARGCNAARGTNYTNGAYYTNTCNGAYCCNGCNMGNYTN MGNGTNGGNTTYGGNCARCCNGAYTTYGGNTTYGGNCARAARCCNAAYTAYATGGTNGTN GAYACNGAYTAYGARACNTAYAGYYTNGTNTAYTCNTGYAGYACNYTN---TTYATHCCN TTYAARYTNGARGGNGCNTGGATHYTNACNMGNACNMGNGGNGCNMGNCCNCCNAAYACN TTYGARYTNGARAARAARYTNGCNTCNTAYGGNATHAAYACNAARTAYTTYAARATGGTN GAYCAYAAYAAYTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------AARTGGYTNTGY ATHTGYYTNACNAAYTGYAARTAYGAYGTNGTNMGNMGNACNTCNMGNAARTTYGGNTTY AARGARGTNGCNGAYGAYGARGAYTGGACNYTNTAYTGGACNGAYTTYTCNGTNGCNYTN GARMGNGTNATGGARATGAARAAYTAYCARAARATHAAYCAYTTYCCNGGNATGAAYGAR ATHTGYMGNAARGAYATGYTNGCNMGNAAYYTNAAYMGNATGCARAARYTNTTYCCNAAR GARTAYAGYGTNTTYCCNAARACNTGGTGYYTNCCNGCNGAYTAYGGNGAYTTYCARGCN TAYACNMGNCARAARAARAAYAARACNTAYATHYTNAARCCNGGNTCNGGNTGYCARGGN MGNGGNATHTGGGTNACNAARAAYCCNAARGARATHAARCCNCAYGARCAYATGATHTGY CARGTNTAYATHAGYAARCCNTTYYTNATHGAYGGNTTYAARTTYGAYYTNMGNATHTAY ACNYTNGTNACNTCNTGYGAYCCNYTNMGNATHTTYGTNTTYAARGAYGGNYTNGCNMGN TTYGCNACNAAYAARTAYGTNGARCCNAGYCAYAAYAAYACNGAYAAYGTNTAYATGCAY YTNACNAAYTAYGCNATHAAYAARCAYAGYGARGAYTTYATHMGNGAYGAYGARGCNGGN AGYAARMGNMGNATHAGYACNATHAAYMGNTAYYTNAAYGARAARGGNTAYGAYGTNGAR MGNATGTGGGCNGAYATHGAYGAYGTNATHATHAARACNGTNATHTCNGCNCAYTCNGTN YTNAARCAYAAYTAYMGNTCNTGYTTYCCNAAYCAYATHMGNGGNTCNGCNTGYTTYGAR ATHYTNGGNATHGAYATHYTNYTNGAYAARAARYTNAARCCNAGYATHYTNGARGTNAAY CAYTCNCCNAGYTTYACNACNGAYGCNGAYYTNGAYMGNGARATHAARGGNACNYTNGTN TAYGAYACNYTNMGNYTNATH--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNMGNMGNGTNGTNGGNGGNAARGTN YTN---AARAAYACNTGGCCNTGGYTNGTNTCNATGCAYTTYYTNGGNAAYCAYCCNTAY CARMGNYTNCARGGNYTNAARCAYYTNTGYGCNGGNACNYTNATHAARCCNCARTGGATH YTNACNGCNGCNCAYTGY---TTYYTNAARGGNGTNTTYAARGGNYTNGARAARCCNGAY AAYTGGGTNGCNGTNYTNGGNGARTTYAAYMGNAGYGTNGAYGARCCNTCNGARCARMGN ATHAARGTNAARGARATHTTYATHGGNCCNAAYATGACNYTNGAYCCNAAYTTYACNGGN GAYGTNGCNYTNYTNAARYTNGARCAYCCNGCNAARATGACNYTNGAYGTNATHCCNYTN MGNYTNGAYYTNAAYMGNMGNATHGGNGTNGGNACNTTYTGYMGNGCNGCNGGNTGGGGN CARCARAARGARGCNCARGARAARGAYCCNGCNTAYGGNAAYGGNACNTAYGTNCCNCAY GTNATHAARATHAARATGGTNTCNCARGCNMGNTGYAARAARGCNTAYACNGGNCAYTTY GCNYTNATHGAYMGNACNATHATGTGYTTYACNTCNAAY---MGNAARGAYACNTGYCAR GGNGAYTCNGGNGGNCCNYTNGTNTGYGARATHMGNAARGGNYTNAARGTNYTNACNGGN ATHGTNTCNATHGGNCARGGNTGYGCNCARAARGARTTYCCNGGNGTNTAYACNMGNGTN GCNMGNTAYMGNMGNTGGATH---------------------------ATGMGNMGNMGN YTNGAYGAYCCNCARYTNYTNACNGTNGAYACNGTNTGGAAYATGYTNATHTCNTTYMGN GARGTNCARGARTAYAARGCNATGATHAARYTNGTNGARGAYGTNGARAARAGYACNAAY GTNAARATHGAYTGYAAYCARGGNATHCARAAYATGTAYGCNTTYGCNYTNAAYMGNAAY GGNAAYMGNGARAARGCNYTNACNGTNATHYTNAARGCNGTNGARAARTCNGARACNCAR GTNCCNGAYATGATHTGYYTNTGYGGNMGNATHTAYAARGAYAARTTYGTNGAYTCNGAY TTYACNGAYCARGARGCNYTNTCNAAYGCNATHGAYTGGTAYMGNAARGGNTTYGARGTN CARCCNAAYGARTAYGCNGGNATHAAYYTNGCNACNYTNYTNGTNATHTCNGGNAARGAY TTYGCNTCNTGYGCNGARYTNCARMGNATHGGNATHACNYTNAAYATHYTNATHGGNAAR AARGGNAGYYTNTCNTCNYTNACNGAYTAYTGGGAYGTNGCNACNTTYTTYGARATHAGY GTNYTNGCNGARGAYTAYTCNAARGCNGTNCARGCNGCNGARTGYATGGARATHCARGAR AARAAYGTNMGNYTNTGGTAYGTNTGGCAYGAYGARGGNGAYCAYMGNCCNTGYGAYTGG ACNTTYCCNGGNGAYACNATHAARMGNGTNAGYYTNTAYAARMGNGAYGCNMGNGCNGTN TTYGTNTAYGTN---TGYAGYMGNCARACNCCNCAYAARTTYATHATHYTNGGNYTNGAY TGYGCNGGNAARACNAGYYTNYTNTAYMGNYTNAARYTNGGNGARGTNGTNACNACNATH CCNACNATHGGNTTYAAYGTNGARACNGTN---ACNACNACNGGNATGGARTTYATHGGN TGGGAYATHGGNGGNMGNGAYAARYTNMGNGCNYTNTAYMGNCAYTAYTAYCCNGGNACN TCNGGNTTYATHTAYGTNATHGAYAGYACNGAYCARGARMGNATHCAYGAYGCNTTYMGN GARYTNCARGARTAYGTNYTNATGAGYGAYGARACNCARAAYTCNGTNYTNATGATHYTN GCNAAYAARCARGAYYTNGARCAYGCNYTNAGYCCNGCNGARATHGARGARAARTTYAAR GARYTNTGYAARTTYAAYGCNACNATHACNACNTTYGTNATGCCNACNAGYGTNACNGAY TCNGAYTCN---TCNYTNCAYAARGCNTTYGARAARTTYGCNAAYATGGTNGCNGCNAAR AARCARGGN------------ATGYTNTCNGGNYTNATHTCNCAYGCNTGGGARGARGAR GARGGNAARGARTCNAAYTCNGGNAGYGGNTTYYTNCAYGARATHAARAAYCCNTTYTCN ATHATGAARTCNGTNYTNTTYTAY------------------------------------ ------------------------------------------------------TTYTGG YTNYTNATHYTNTTYGCNATGATGTCNTGYTTYGGNGCNTGYGGNTAYTAYMGNMGNMGN MGNATGGCNTTYTTYMGNATHGAYCCNTCNGTNTAYGGNAAYGTNTCNGTNAARTGYATH GCNTCNAAYCCNAARTTYCCNCARATHAGYTGGATHAGYGTNCARGTNCCNCCNCCNTAY CCNCCNGTNGTNACNGTNAAYGGNATGYTNCARAAYYTNAGYACNGTNMGNYTNTCNGCN AAYAAYCCNGCNACNGTNCARTGYMGNGTNGAYGGNGGNTAYCCNAARAGYGGNYTNATH GGNMGNAGYTTYGCNATGYTNTTYGCNAGYGCNGGNTAYGAYGTNGTNATHTAYGAYGTN GARCCNAARCARACNAGYGCNGCNAARGCNGAYATHAARACNCARYTNAGYGCNYTNCAR AARGARGGNYTNYTNMGNGGNAARYTNAGYGAYGTNGARCARTAYGAYAARATHTCNACN ACNGARAGYYTNGARGAYTGYGTNMGNGGNGCNTTYTTYGTNCARGARTGYGTNCCNGAR MGNYTNGARATHAARMGNTCNGTNTGGTCNAARATHGAYAARATGGTNGAYGGNAGYGTN ATHATGTCNACNTCNACNAGYGCNYTNYTNCCNTCNACNATHTCNGARGGNYTNACNCAY AARAAYMGNTTYATHGTNTCNCAYCCNACNAAYCCNCCNTAYTAYGCNCCNGCNACNGAR GTNGTNCCNGCNAARTGGACNGAYGARGARGTNATHAARAARACNGTNGARGTNYTNAAR GARATHGGNCARGTNCCNATHYTNGTNAARAARGARGTNGAYGGNTTYGTNYTNAAYMGN YTNCARTAYGCNATHATGGGNGARGCNTAYMGNYTNATHCARGAYGGNGTNGTNAGYGCN ACNGAYYTNGAYYTNATHATGTCNCARGGNYTNGGNYTNMGNTAYGCNTTYATGGGNCCN TGGGARACNGGNTAYYTNAAYGCNGARGGNATGATGGTNTAYGGNGARMGNTAYGCNGAY ATGATHYTNAAYATHCARAARAGYTTYAARGARCCNACNMGNATGGARGGNCARACNYTN CARTCNATHCARAAYGARATHGARCARATHGCNGGNCCNGTNGARGARATHAAYGTNMGN MGNCARTGGMGNGAYMGNMGNYTNGTNGCNYTNGCNAARYTNAARGCNCARATGGAYMGN GCNGARGARAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARGGNCAYYTNTTYTGYAARGARTGYGTNACNMGNTCNACNGARGCNGCN TTYGGNGARATGAARACNMGNTTYCCNTGYYTNTAYGGNGAYTGYGAYCARGARATHTCN YTNAAYACNYTNCARGARATHATHCCNCCNAAYYTNTTYTCNAARATHGTNAAYMGNYTN CARGARGARGARATHYTNAARGCNNNNATHCCNGAYYTNGTNNNNTGYCCNTTYTGYCCN TTYGCNACNATHATHCCNGAYYTNGARTAYAARATHYTNAARTGYYTNAAYCCNGARTGY YTNAARGARTCNTGYMGNYTNTGYMGNGARGARAAYCAYATHCCNTTYMGNTGYGAYGAR ACNGARAGYMGNGCNGGNGTNAAYATGMGNACNTTYATHGARAAYAARGTNTCNGARGCN GTNATGMGNAARTGYCAYAARTGYGAYAARMGNTTYYTNAARGARTCNGGNTGYAAYAAR ATG--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNACNTGGTGYMGNAAYATHACNGTNACNAARYTNYTNMGNCAR GAYGARAAYGAYGCNAGYYTNGAYTCNGARGAR---GCNAARCCNAARMGNAARGTNGTN GAYGTNGARACNAGYATHMGNTAYYTNAAYAGYAARGCNTTYGTNGARGGNTAYGGNGAY AARCCNGTNTGGTTYCAYTAYMGNMGNAAYTTYAARGGNAAYATHYTNCCNCCNACNMGN AARAARTGYATHMGNAAYGGNGARGTNGCNACNGCNAGYCCNTGYCCNGTNTGYMGNGAY GARTAYYTNGTNGTNAAYGCNAARAAYACNAARYTNYTNGARCARTTYATHTCNCCNTAY ACNGGNGAYATHYTNGAYTCNATGAARACNGGNYTNTGYCARCARCARCARAARACNYTN ACNYTNGARGTNATGAARGCNTAYGAYCARGGNTAYYTNGARATGAARGTNCCNTTYMGN TCNTAYGAYTAYGAYGAYTAYAARAGYTCNAARGTNYTNCARTGYTCNATGGAYMGNGAR YTNATGYTNTAYTGYGAYGTNAARGARCARACNAAYCCNGTNGCNAGYYTNTTYYTNTAY GGNYTNACNAGYCARCCNGTNAAYCAYGARATHAAYGGNCAYMGNAARAAYGCNTCNTCN GAYGCNGAYMGNTCNCCNGAYYTNGAYAAYGAYAGYGAYGAYGAYGAYGGNCCNGARTAY AAYGAYTAYTCNTCNAAYGARGAYATGAGYGAYAGYGARCCNACNATGACNGARGCNMGN GCNMGNCARMGNAARYTNAGYMGNTCNAARTCNMGNGCNGGNGTNACNCARMGNAAYATH AARCARAARTTYMGNGCNYTNYTNMGNAARTTYAARATHTCNGARGAYGCNYTNGTNGAY TCNGARGCNGAYCAYGAYCARATHCCNAAYCCNYTNGAYGARYTNTTYGAYGARYTNGAY GAYTCNGAYTCNGGNCCNGARYTNGAYACNATGAGYGTNATGTCNACNCCNAARCCNAAR YTNMGNCCNTTYTTYGCNAAYMGNAGYATHACNCCNGGNYTNGCNGARYTNCCNAARACN ACNTCNCARGARACNTTYMGNTCNCARGAYGARACNCCNGTNAARGGNTGYGARAARCCN TTYCARGAYYTNATHATHACNGAYACNTCNTTYYTNGARGARAGYTCNTCNMGNACNAAR TGYGARAARTGYAAYAARTCNMGNAARTAYTAYTGYTAYAGYTGYGTNATHCCNYTNCCN TAYATHCARGAYAARYTNCCNAARGTNAARYTNCCNYTNCARGTNGAYATHATHAARCAY CCNAARGARYTNGAYGGNAARAGYACNGCNCCNCAYGCNTCNATHYTNGCNCCNGAYGAY GTNAARATHTAYACNTAYCCNTGYATHCCNGAYTAYGAYTAYGAYAARGTNYTNGTNGTN TTYCCNGGNCARGAYTCNATHAAYYTNGARGARAAYGCNTCNGARYTNACNYTNGAYGAR AAYMGNYTNGARACNGCNCARACNACNTCNYTNCAYTCNGTNGAYAARACNAAYACNTCN AAYTGYTCNGARATGYTNCARAAYTCNAAYACNATHYTNCCNAGYAARATHTCNAAR--- ------------------ATHTCNGARGCNAAYTCNGAYTCNTAYTCNGTNAAYGAYATH GAYACNCARTCNTCNTTYACNATHTCNAAYYTNCAYAARGAYYTNAARMGNAARMGNTCN TGY---------------------------------GAYGARGARGARTCNATHAAYGGN TCNTCNCCNTCNGARCAYAGYATHAARACNYTNAARGARTGYCCNTTYGARAARGTNATH TTYATHGAYTGYACNTGGAAYCARACNAARCARATHGTNGARGAYGARMGNYTNAARGGN YTNAARAARGTNGARYTNAAYTCNCAYACNACNAAYTTYTGGMGNAGYCARGAYGGNATG CCNAARACNTAYYTNTCNACNATHGARGCNATHTTYTAYTTYTTYAARCARTTYCAYACN GTNTTYYTNGAYCCNGTNTAYMGNAAYCARTAYGAYAAYYTNYTNYTNTTYTTYTCNTTY ATGCAYACNAARATHAARAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGNMGNTGYTCNGGNCCNGTNAGYCCNAAYMGNTTY ATHATGYTNGTNATHGGNAAYYTNATHAAYTGGACNTTYGCNYTNTAYGGNGCNATHCAR CARCCNTCNGAYTTYGCNAGYTAYYTNYTNGCNATHTTYATHGGNAAYYTNYTNYTNTAY TGYYTNTTYTAYGTNATHATGAARYTNYTNAGYGGNGARMGNATHAGYGTNYTNGTNGTN TGYGTNATGYTNACNTCNYTNGTNTCNTGGGGNTGYTCNYTNTAYTTYTTYTTYCAYCAY ATHACNTCNTGGCARAARACNCCNTCNGGNTCNMGNGARGGNAAYMGNGARTGYATHGTN YTNGGNTTYTAYGAYTCNCAYGAYGTNTGGCAYTTYYTNTCNGCNTTYAGYYTNTTYTTY TCNTTYATGATHYTNYTNYTNYTNGAYGAYGAYGTNTCNYTNAAR--------------- ------------------------------------------------------------ ---------------------------------------------------------MGN GGNGARGAYMGNACNGAYATGACNCARGCNGARGGNACNGARGAYAGYMGNGGNCARGGN CARTGGAARAGYGCNGARCARCARTAYATHGCNTCNGCNGTNATGGCNCAYAARAGYGAR CARGARGCNYTNAARGARGTNGARGGNGARMGNGAYAARYTNGTNGARGAYAAYCARGAR YTNAARAARTCNYTNGARTCNGTNGARCAYGARYTNGCNAGYAARTGYGAYYTNYTNGTN GCNGARMGNGARATHAGYGCNGCNMGNGAYAARAARATHAARCARYTNAGYGARGARYTN TCN------YTNACNAGYGGNGARGGNAAYGARGARMGNATHAARGAYYTNCARGARMGN YTNGCNGTNYTNGCNMGNGARTGYGARGARAARGAYAARMGNATHAAYGTNYTNGARGGN GAYYTNMGNACNACNAARGCNAARYTNAARCARACNGARGAYMGNYTNAARGCNATHGCN TCNGCNTCNGCNGGNAAYGGNGAYGTNCCNAARTCNAARACNTGYGCNATHATG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNTTYAARAGYGAYYTNACN YTNGARAARYTNTAYCCNAAYTCNAAYCCNGAYTTYYTNMGNCARACN---GARTAYCAR AARTCNGCNGAYAARGAYGAYAARTTYTCNGGNTAYATHCCNATHGARCARATHGARATH TCNCAYAAYMGNAGYAGYGGNCCNGGNGGNCARAAYGTNAAYAARGTNAAYAGYAARGTN GARATHMGNTTYCAYGTNGAYTCNGCNTCNTGGATHCCNCAYTGGATHAARCCNMGNYTN GTNGARCARGARCARAAYMGNATHACNAARGARGGNATHYTNGTNATHAARTCNGAYATG ACNMGNAARCARATGYTNAAYCARGCNGAYTGYYTNAAYAARYTNMGNAAYATGATHCAY MGNGCNTCNGTNYTNCCNAARGARCCNACNGARGARGARATHMGNATHAARGARCARMGN YTNATGAARGCNAARGCNGGNATHYTNAARGARAARMGNAAYAARTCNYTNYTNAARAAR TCNMGNTCNGCNCCNGARYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TAYCAYMGNGTNATHTGYCCNACNAAYCARGAR TCNACNTCNGGNATGYTNTAYGAYGTNMGNTGGTCNTTYAARGAYGTNATGGTNACNGAR GGNGTNTCNYTNAARGGNTGGTGGAAYACNAGYTTYAGYCCNATHYTNYTNTCNMGNATG TGGGCNATGGTNYTNAGYAAYGCNGTNMGNATHGCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TAYYTNAARYTN YTNAARGARGAYGGNAAYGTNTCNGAYTGGYTNACNTCNATHATHGARYTNAARAAYTCN GTNATHGGNAGYAAYMGNGARAARGCNMGNGTNATHCAYCAYGGNYTNGTNCCNMGNYTN YTNAARTGGATHGARGAYGAYGGNTGYCCNAGYGAYYTNAARACNGARTCNGTNATHGTN YTNGGNAGYYTNGCNAARGGNGGNCAYGARGCNGTNCARCARYTNGTNCARTTYAARGTN ATHCCNACNYTNYTNMGNTCNYTNTCNGCNTCNAGYYTNMGNCAYAGYGARAGYGTNYTN CARTGYYTNMGNTCNATHTTYATGGARAGYACNGAYTAYGTNGAYTGYYTNTAYCARGAR TCNAARTTYGGNGCNTCNTAYATHCCNATGYTNYTNTCNYTNATHCARMGNTCNGARGTN TGYCARGARTGYGTNGCNAAYATHYTNGTNTGYTGYTGYAARACNAARGAYCAYCARATG TGYYTNTTYTTYAAYCARGCNYTNCCNAGYYTNGGNCCNYTNYTN---CARTCN---TCN TTYAARATHCARATGCCNACNYTNAARTGYTTYGCNAARATGTCNTAYAARAAYGARGAR GTNTGYMGNGCNATHGCNMGNGARAGYGARYTNYTNGAYTGYTTYAARGAYYTNATHGGN MGNGAYAARCCNGGNGARATGCARYTNTCNGCNGCNGARGTNTTYACNAAYYTNCAYMGN TGYGGNGTNGTNCCNGCNTCNGARTAYATHATHAGYMGNAARACNYTNGGNACNYTNGTN MGNATGTGYYTNCARGAYMGNTCNGTNCARGARAAYGTNMGNGGNGCNGARATHYTNGCN TAYYTNGTNGARATHGAYCCNGGNYTNCARYTNATGGCNAGYTAYACNTTYCAYYTNATH AGYACNYTNTCNTAYTGYYTNCAYTTYCARAAYCARGGNAARMGNTCNAGYGGNGGNAAR CARGARGTNGAYTGGAGYAGYGARATGMGNMGNGCNGCNTTYYTNGCNTTYGCNTCNATH AGYGCNAAYGAYGARGARATHMGNGARAARGTNATHAARCARGARGGNYTNATHGARCAY YTNCARAARTCNGTNTCNAGYCCNAAYGARGGNGARGTNGCNGCNAGYYTNMGNTGYYTN CARTCNYTNACNMGNTCNGTNGTNMGNGAYMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGTCN ACNTAYATHMGNMGNTAYGCNAARTAYYTNAAYGARAARGCNGTNTCNTAYMGNYTNATG GCNTTYGAYTTYTGYAARGTNAARMGNGGNAARGAYGAYGGNYTNYTNMGNACNATGAAY ACNGARAARYTNYTNAARACNYTNCCNATHYTNCARCARCARYTNGAYGCNYTNYTNGAR TTYGAYTGYTCNCCNAAYGARYTNACNAAYGGNGTNATHACNGCNTGYTTYATGYTNYTN TTYAARGAYYTNATHMGNYTNTTYGCNTGYTAYAAYGAYGGNATHATHAAYYTNYTNGAR AARTAYTTYGARATGAAYAARAARCARTGYAARGAYGCNYTNGAYYTNTAYAARAARTTY YTNGTNMGNATGGAYAARGTNTCNGARTTYYTNAARGTNGCNGARAAYATGGGNATHGAY AARGGNGAYATHCCNGAYYTNGCNAARGCNCCNGCNAGYYTNYTNGAYGCNYTNGARCAR CAYYTNGCNTCNYTNGARGGNAARAAR---ACNGCNACNACNCCNACNGGNTCNGCNAAR CCNTCNGGNTTYACNACNGCNYTNAAYAAYATGTCNAGYAAYACNTTYAAYGTNAGYGAR GCNGARAARAARAARATHYTNGARGARGARAGYCARCARYTNCARAARCAYAARGGNGGN CARCARGAR------AARGTNAARACNGAYYTNTCNCCNCAR------AARGCNGTNTCN GCNAAYAAYCCNTTYTCN------AGYCCNACNTCNTCNTCNGCNCARCARGAYYTNTTY GGNTCNCCNATH---------AAYGCNGCNAGYAARGCNAGYGAYGAYYTNYTNAGYYTN AGYGCNAAYCCNTTYGCNGAYAAYGTNGCNTCNAAYGCNTAYTCNTCNCARACN------ ---------TCNAGYAGYAAYCCNTTYGGNACNCCNGCNTTYCARACNAAYGGNTAYTCN GGNGCN---------------TTYGAYGCNGAYTTYGCNAGYGCNTTYAAYAAYGCNGGN ACNAAYTCNCARGTNCCNACNGCNGCNCCNTCNTCNACNGCNCCN---------CCNGGN TTYGAYGCNTTYGGNGARGTNATGACNCCNATGAAYAARTCNCCNTCNCAYCARGCNCAR GGNAAYCARGCNGGNMGNGCNYTNGGNGGNGAYYTNGAYTCNTCNYTNGCNTCNYTNGCN TCNAAYYTNACNGTNAGYGGNGGNACNGGNCARYTNAARAARGAYCAYCARTGGCAYCCN AARGGNGARAGYAARYTNACNGGNGGNCARTCNTTYCARMGNCCNCCNATHGCNACNTCN ACNACNACNGCNGCNCCNCARTGGGGNCARCARCCNGGNTTYCARCARCCNATGYTN--- ---GGNGCNGTNCCNGGNGCNCARATGATGTAYGGNCARCARATGGGNATGCCNGTNGGN CARCCNATGATGATGCCN------CCNCARCARATGGGNATGCARCCNATGGGNYTNATG GGNATG------------CARCARCARCCNATGATG---TAYGGNGCNCARCCNCCNCAR ATGCCNCARACNCARCCNATGGCNCARTCNAAYGCNAAYGAYCCNTTYGGNGCNYTNGAR TCNMGNAARMGNYTNMGNCCNTGGYTNYTNAARAARGTNAAYGARGGNYTNGGNYTNMGN TGGATHGAYMGNMGNGARGARATHTTYAGYATHCCNTGGGCNAAYAARAARAAYMGNTGY TGGGAYGARTCNTAYTGYCARGTNTAYAARGARTGGGCNAARTAYACNAARAARTAYGTN GAYGGNCARCCNGARGAYTGGCCNGGNTGGAARACNMGNYTNMGNACNGCNYTNAAYAAR YTNCCNGAYTTYGARGARATGGAYAARATGCAYCARYTNGAYATHGAYAARCCNTTYMGN GTNTAYMGNTTYGTNATGGCNAGYMGNCCNAARTCNGGNATHACNGCNAAYACNGAYGTN AAYYTNGAYTTYYTNACNAARGARGARAARGARGCNYTNYTNTCNAARAARATGGAYATG ATHMGNCARCARAAYMGNYTNATHAAYGARMGNCAYGARATGATHGARGCNGAYMGNMGN AARGCNGARGARACNGGNAAYGCNGTNAARGCNATGGAYAGYAARACNYTNCCNGCNGAR GGNGCNCCNAARTCNAARGGNMGNGGNMGNGGNCARAAYCARGGNTCN------------ AAYAARGAYGGNAGYMGN---ACNAARGCNMGNTCNAARTCN------------ACNTCN TAYGARCCNATHGTNGAYGTNAGYGAYTTYTCNGTNMGNGTNGAYAAYACNMGNAGYAAR GGNAARGGNGGNCARTAYTAY---------CAR------------------GARAARGAY AAYTCNTCNCAYACNCCNAARAAYMGNMGNAARCCNCAYCAYAARGAYGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNTAYAAYGCNGGNTAYGCNMGNTCNAAYMGNMGN--- ------------------------------------------------------------ ---------AGYGAYACNAAYCCNCCNCCNGAYCCNTCNTTYAAYCCNYTNTCNGAYCAY MGNMGNGGNGGNGGN---TCNGAYMGNAARGARGGNTTYGARMGNCARGAYMGNTCNGAR CAYAARMGNCAYCCNMGNAAYTAYGGNGGNGGNGCNGAYYTNGGNAARGTNAARGAYAAY ATHAARAAYATGMGNGARAARGARMGNGAYMGNYTNGGN---AAYAARCCNYTNGAYATH ATGATGACNGGNMGNGARMGNAARAAYCAYGARCARTGGAARCARGARMGNGAYMGNTAY GAYAAYGARMGNATHCARMGNCARYTNACNGAYGGNGGNGGNTGGMGNMGNGARTGGGAY CARGAYAARGTNGTNATHGAYTAYGAYGAYGGNGCNCAY------TCNAARTCNGARCCN GCNAARMGNCCN------------------------------------------------ ------------------------------GCNGGN------------------------ ---------------------------------------------------------MGN ATHGGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNAAYGGNMGNAARGCNTCNGTNACNMGNCCN GCNAARGARCAYACNTTYYTNACNGAYGTNGCNAAYGTNMGNACNATGGARCAYGGNYTN YTNTCNYTNYTNAAYGAYTTYCAYTCNGGNAARYTNCARGCNTTYGGNAGYAAYGCNACN TTYAAYAARATGGAYGCNATHMGNATHCARCARGARCARYTNGCNAARCARCAYTTYGAR YTNGAYYTNYTNCCNMGNTCNGCNTCNAGYMGNYTNAAYACNGARGARGCNMGNAARGAR AAYAGYGARAARATGGAYAARYTNATHGARCARTGYGAYYTNYTNATHATGGCNAARATH AAYGTNACNATHAARGTNATHTGYGCNATHAAYAAYCARAARCCNATHGTNATGCCNGAR TAYYTNAAYCAYYTNTAYCARTAYYTNATHGGNMGNGARAARCCNGAYCCNAARGAYTAY YTNCCNGARGTNGTNGAYAARGARGTNCCNGCNGGNGTNTCNTTYCAYCCNGAYATHMGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHGAYGCNAAYGCNCCNMGNCCNGARCCNGTNTAYYTNMGNMGNGAR AARCARCARCCNCCNACNYTNACNCCNTCNAARCAYCCNCAYGGNAGYAGYCCNACNACN AAYAGYCAYCCNCAYACNGGNCARGCNMGNCCNYTNGTNTGYGGNAAYGAYAAYAGYACN GTNAGYMGNCARTCNMGNACNCARACNACNMGNCCNGAYCCNATHCCNGGNCARCCNTAY GCNGGNGCNCCNGCNCARMGNATHGGNAGYGCNCCNYTNMGNAARGTNGGN---AAYCAR GGNACNATHMGNCAYGCNGCNGGN---------AAYMGNTCNGARYTNGARCCNGGNGAR ---------CARGTNCARTCN--------------------------------------- CARCAYCAYGTNGAYTTYYTNCCN------------------CCNATGCCNMGNCCNCCN CARGCNTCNGTNGGNGAYGAYTCNATGYTNGAYCARAGYMGNCARATGACNACNGTNCAR GARYTNGARMGNCARTTYCARGGNATGCCNATGCCNTCNGCNCCNGGNMGNCCNGARATH AGYCCNCAYTCNAARAARYTNTGGGAYGAYGAYTCNAAYAARGCNGGNGAYCCNAAYAAY TCNGGNATGTTYCAYCAYGGNTGGCCNACNMGNGAYGAYTCNTGGATGACNGGNCCNTCN GARTCNAGYAAYCARATHGGNGTNAAYATGGTNGARTAYGTNYTNGGNGGNGGNTCNCCN AAYAARATGGAYGCNGGNGCNATGGGNMGNATHAARTCNTAYGAYGAYAARAARAAYGAR AAYGTNACNCARTAYGARGARAGYGTNGAYGAYGGNAARGAYGGNYTNCARGCNAAYAGY ATGYTNCCNAAYGGNYTNGAYGAYACNGGNTTYMGNGGNAGYMGNCARAAYTCNCCNACN GAYGAYGARMGNCARGGNGTNGTNGGNATGCCNATGGAYCCNCARGAYATGCAYYTNMGN GAYCCNGGNAAYTTYYTNGAYACNGGNCAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TAYTCNTCNGCNAAYGGN TAY---GCNCCNTCNTAYCCNAGYCAYCCNAARGGN------------------CAYCCN CCNATGTCNCARCARTCNCARAAYTCNTCNTTYCCNGGNCARTTYCCNGTNAAYCARTCN ---TAYCCNCCNACNGGNCARACNCARTTYCARGCNCCNCCNAAYGCNGCNCCNTTY--- CCNACNGCNCARCCNTCNCCNTAY---------AAYTCN------TCN------------ AAYTCNTCNCARAAYCARTTYTCNTCNGGNCCNAGYCARTAYTCNGTNYTNTCNCAYCAR ACNCARTAYCCNTCNAGYGGNCARAAYACNTAYGGNAGY---GGNCCNTCNCARTAYGCN GCNTAYCARAAYAGYAAYTCNTTYCCNCCNCAYCCNCARTCNCARTCNAAYTTYCCNTCN AAYCARAAYGGNACNACNGGNGCNACNYTNTAYCCNTCNTCNACNCCNTCNAGYGTNCCN TCNTAYTCNTCNCARTCNAAYTCNTAYCARTCNCCNTCNGCNGGNTCNTAYCAY---GCN MGNGARGGNTCNTCNAAYATHGTNGCNAGYACNCARTCNAGYTCNAGYATGCCNTTYCCN GCNCARCCNCARGCNTCNAAYYTNAARCCNGCNTCNTCNCARAGYTCNTCNAAYTTYAAY ACNCARCAYTAYAAYAAYACNCCNGCNCCNYTNCARCCNTCNTCNYTNGCNAAYAARYTN GGNGARAGYYTNTCNAARATGACNYTNAARGAY---ACNGCNGTNYTNGAYAAYCAYCCN TCNACNCARTAYGARCAYCCNTCNTCNACNTCNAGYGTNCCNACNGCNGTNAGYYTNCCN TCNGCNTCNTCNTCNGCNTCNYTNTCNACNGGNACNAAYACNATHTCNTCNATHTCNACN GTNACNTCNGCNTCNTCNAGYTCNMGNGTNACNTCNATGCCNTCNACNTCNGGNAARGCN CCNCCNAAYYTNCCNCCNGGNGTNCCNYTNGTNGGNCARTAYATHATGGGNCARAAYACN ATHCCNCCNTTYTAYAGYGTNCARCCNCCNYTNTAYGGNTAYGARGAYATGCARYTNYTN CARCARMGNATGCCNATGCARACNGGNAGYTTYTAYGAYGTNAGYGCNTTYCCN---GCN CCNGCNGGNTCNACNYTNCCNTCNGGNMGNGAYCARCARCARCCNATHCCNAGYGTNCCN TTYTCNGGNCCNTCNGAYACNAARYTNACNMGNGTNGAYGCNCARAGYCCNAAYGCNTCN AAYCARCCNCARAAYGCNCAYTCNGCNCARCARCCN---YTNTTYAAYTTYCAYTAYGGN TAYTAYTAYCCNTCNATGTTYCCNGGNGCNGCNGGNYTNCARTAYCCNACNACNGTNTAY CCNATHCCNCCNGTNACNAAYACNGCNGCNCAYCCNGGNACNACNTCNACNACNCARTTY CARAARTCNTAYCCNTCNCAYATHTAYACNACNAARGGNTAYGAYGARYTNAAYCARGTN CARGAYTTYTCNAARACNGGNTAYGGNAGYTCNCARAGYTCNGGNAARGCNGCNGGNACN MGNATGTCNACNMGNTCNGGNACNAAYGARATHACNCCNAAYGTNTAYAGYAARTCNCAY GGNCAR---GGNTTYGAYAARCARGCNTAYCAYGGNGGNACNCCNCCNCCNTTYAAYYTN CCNATGGCNTCNGCNGCNCARACNGGNCCNATGGGNGCNCCNACNACNCCNTAYGGNGGN ACNTTYYTNCCNGTNATGGCNGCNCAYCARCCNCAYTCNCARATGATGCAYCAYCCNATG CARCARGAYTCNAAYACNAGYAGYTCNMGNGGNATGAAYCCNGCNGGNGGNCARGCNAAR TCNGGNGCNGCNAARGCNTTYGGNGGN---CCNCCNTAYTGGAAYAAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNAARTTYACNCCNGAYATGATHYTNTTYTCNGAYYTN GCNGARYTNGTNTAYGTNATHGTNGAYYTNGTNGCNTTYTTYYTNATHTTYATHGCNGCN TGYATHYTNTCNGCNGGNACNAAYTCNACNTGYGAYGTNGTNAAYTGYGAYATGTCNGAY GCN---------ATHTCNGCNTCNMGNGCNGCNCARGCNGGNGCNTGGATHAGYACNTTY YTNTGGYTNTTYATHGGNGTNTGYGGNTTYATHACNYTNTGGMGNGCNGGNAARATHCCN TTYYTNCCNGGNAGYGGNGGNGCNAARTCNGAYCARGGNACNGGNCCNACNGAYCCNAAY CARCCNCARATHGARACNCCNCCNAGYAAYCCNGAYGAYCCNCCNAARTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CCNCARGCNGCNAARGAYGARGARCAYATH GCNAAYGCNGTNAAYCARATHYTNGCNCARGCNGTNCARCARCARMGNGARYTNACNYTN GCNGCNCARAAYCARCCNCCNCCNCCNCCNAARAGYMGNAGYMGN--------------- TAYAARTAYMGNATHCARMGNMGNYTNTAYCAYGGNTGY--------------------- AGYGARAARGCN---GTNTCNACNACNTCNYTNCCNYTNACNGARGTNTCNATGGAYTAY TTYCARGAYAGYTTYGAYGGNGCNGARGGNYTNGGNMGNYTNGAYATGCCNATGACNACN GCNATHACNAARAARAAYAARGTNTCNCCNTGYTCNGTNGTNYTNTCNATGYTNTAYGCN AARMGNYTNMGNCARMGNAAYMGNCARTAYYTNCARTCNATGTCNTCNACNGAYGTNTTY TTYATHTCNATGATGATGGCNAGYAARTAYYTNTAYGAYGARGGNGTNGAYGARGARGTN TAYAAYGAYGARTGGGCNGAYAGYATHGGNCARGARGTNGARGAYGTNAAYCARATGGAR ATGGAYTTYYTNMGNGARATGGAYTGGCARYTNTTYGTNAARCCNGAYGARTTYGAYTCN GCNYTNACNGCNGTNGARMGNMGNYTNGCNYTNAARGARGGNATGAARMGNGGNTGGTTY ACNTAYACNGARATGGARGTNYTNYTNGAYTGGGAYCCNATHTAYCARATGTGGAGYCAR TTYACNAAYGAYTGYACNAARGTNGTNTCNGTNYTNTCNGCNGTNTAYGTNGCNGGNYTN YTNAGYATGATGGGNTCNGCNGCNATHGCNYTNCARYTNTCNGTNCCNATGGCNACNGCN ACNGTNTCNATHYTNTCN------------------------------------------ ---AARTGYTGYCCNMGNGCNTGGAAYTAYGGNTGYMGNCAYGTNAAYTAYMGNYTNCCN TGYTTYMGNAAYTAYTTYCAYGGNMGNMGNGARACNTGYTGYCCNATHTGGCCN------ GCNGTNTAYACNGCNMGNTGYTCNTGYAGYACNTGYCAYATHMGNACNAGYACNTGYATH CAYMGNGGNMGNTGYAAYAGYMGNTAYACNMGNMGNAAYTTYGTNGCNGTNTGYTAYGGN MGNTGG---AGYTGGAAYYTNMGNTTYTTY---CARAARTGGATHCCNTCNAGYTGYTAY TGY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGTNTGYGTN CCNTGYTTYYTNATHCCNATHATHYTNTGGATHTTYCAYAARTTYATHCARCCNTGGYTN TCNAARATHTGGAGYGGNTCNGARACNTAYGTNACNAGYAAYYTNACNTGYCCNYTNCCN CARAARAARAAR---------------AARAARATHGAYGCNTCN--------------- ---------------ATGGCNACNGCNGGNTTYTAYMGNGGNACNAAYGCNGARCARGAY ATHMGNTTYGCNGAYAARCARAARAARYTNATGAARTCNATGAARTTYGGNGARAAYATH GAYAARAARATHGAYATGACNAARGTNAAYGTNGAYAGYATHAARCCNTGGATHGCNCAR MGNGTNACNCARYTNYTNGGNYTNGARGAYGAYGTNGTNGTNGARTTYGTNTAYAAYCAR YTNGAYACNMGNCAYCCNGAYGGNAARGAYATGCARATHYTNYTNACNGGNTTYYTNAAY AGYAARAAYGCNMGNATHTTYGTNGCNGARYTNTGGAARCAYYTNAGYAGYGCNCARGAR AAYATHACNGGNATHCCNTCNGARTTYYTNGARCARAARAARAAYGARATHAARCARMGN CARGARGARCARGARMGNYTNCARGARCARYTNAARCARAARGARGARYTNATHAARGAR CARYTNTCNMGNGARMGNMGNGARATHGARAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNAAYYTNMGNGGNGCNGCN TAYCCNCARTTYGCNTGYCAYAARAGYMGNYTNCARAGYTTYYTNTTYTGGGAYCCNAAY CAYAAYCARAARCCNAARGARYTNGTNAARYTNGGNTTYTTYTAYGCNGGNTAYTCNGAY TGYGCNMGNTGYTTYTAYTGYGGNYTNGGNYTNAARTAYTGGMGNCCNGARGAYGAYGCN GCNTAYCARCAYGCNMGNTTYMGNCCNCAYTGYACNTAYAAYCARTTYGTNAARGGNCAY GAYTTYATHGAYCARGTNCARMGNGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARAARACNGARGTNTTYYTNGARATHCAYGGNAAYACNYTNYTN MGNCARCARACNAGYGAYTAYATHAARAARATGTCNCARCARYTNATHMGNATGGTNACN GAYTTYGAYTAYTTYGARAARAARYTNGCNATGTTYGAYYTNAGYCARYTNAARTAYAAR GARMGNGAYTTYYTNGARGGNGTNTTYAARTTYTGGMGNGAYAARGAR------AARAAR CCNTTYGARATHTCNAARTGYTGGGARYTNMGNCARMGNCARYTNYTNGGNGTNMGNTAY GAYAGYMGNCCNAAYGCNTTYGAYTGGGAYTAYAAYATGGARATGYTNGARMGNGGNGGN TCNATHATHCAYYTNMGNCARTAYAARGCNTGGMGNGARGAYGGNATHGCNTAYACNATH MGNGARGGNACNTAYGAYGTNCCNAAYMGNACNYTNTCNTCNGCNATGGTNTTYAARCAY GARGGNGARMGNCAYCCNMGNMGNGGNTGYTGGGGNGAYATGYTNGTNTCNCCNTAYYTN ACNTTYGGNGTNGARACNGARGARAARTCNYTNTAYAARAARCARAAYGAYCARCAYACN AARACNGCNGARGAYGTNGCNGARCAYAAYATHYTNTCNYTNYTNCAYGARYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CAYYTNCARGCNCCNYTN AARTAYATHGARMGNTTYAARTAYATHGARAAYAARCARMGNMGNACNTAYGCNGCNATG ATGTCNGCNYTNGAYGAYGCNGTNGGNTCNGTNTAYGAYACNYTNAARACNTCNGGNYTN YTNTCNAAYTCNATHATHGTNTTYACNACNGAYAAYGGNGGNCCNGCNAAYGGNTTYGAY TTYAAYGCNGCNAAYAAYTTYCCNYTNMGNGGNGTNAARGCNACNYTNTGGGARGGNGGN GTNMGNGGNGTNGGNTTYGTNCAYAGYTCNYTNYTNAARCARMGNGGNTAYGTNGCNAAY CARATGYTNCAYGTNTGYGAYTGGYTNCCNACNYTNTAYACNGCNGCNGGNGGNAAYTCN TCNGAYYTNAARAAYYTNGAYGGNTAYGAYGCNTGGGARATGYTNAAYTCNAAYGGNCCN GCNGTNMGNCAYGARATHYTNCAYAAYATHGAYCCNYTNGGNAARCARGCNGCNATHMGN GTNGGNGAYTAYAARYTNYTNACNGGNGGNATHAGYYTNCAYTGGGGNGGNTGGTAYCCN CCNTGGACNYTNGAYCAYGAYGAYCARYTNYTNCAYTAYACNAAYGTNATGGAYAGYATH ACNGAYGARGARGARTTYTAYTAYYTNMGNCAYAARYTNGAYATGGARTAYAARAAYTTY TGGCCNACNGAYGTNAARATHMGNYTNAARACNYTNTAYGAYGARGGNCARAARATHAAR AAYGAYTTYGARGAYGAYCARAGYYTNTTYGAYCARGGNCARGGNACNCCNGTNAARGTN GARTGYMGNGAYAARCCNGTNAAYGCNAGYATGAAYTGYCAYCCNGCNAARTTYGTNTGY YTNTAYAARGTNACNGARGAYCCNTGYGARTAYCAYAAYATHGCNGAYCARCAYCCNGAY ATHGTN---------------------------------------------GCNGTNCAR MGNCCNMGNGGNATHTCNYTNGARAARGCNTCNTTYTAYCARCCNGARAAYGAYTTYMGN TGYYTNACNGAYGGNAARATHYTNCCNTTYGAYCAYGTNAAYGAYGAYTAYTGYGAYTGY GARGAYGGNTCNGAYGARCCNGGNACNTCNGCNTGYGCNAAYGGNYTNTTYTAYTGYGAR AAYAARCCNTAYAARGGNGTNTAYATHYTNTCNTCNMGNGTNAAYGAYGGNATHTGYGAY TGYTGYGAYGGNTCNGAYGARTTYGAYGGNACNATHACNTGYCCNAAYACNTGYYTNGAR YTNCARCARAARGARMGNTCNGARCARGARGTNTTYAARMGNGTNCARGCNGARGGNTAY AARGTNAARCARGARTAYATGCARCARGGNAARMGNGCNAARGAYGARAARYTNTCNAAR YTNAGYGARYTNGARMGNGARAARGAYTCNYTNGCNAARGARAARGAYGCNGCNGARGTN GCNAARAAYACNGCNGARGARCCNGARAARATHGCNATHGARGARCAYAARAARGCNTGG GARYTNATHAARGARGARMGNAARAARGCNAARGARGCNGCNGAYGCNGCNYTNGCNTTY AARACNYTNGAYGCNAAYGGNGAYGGNAARGTNGAYTTYCCNGARYTNATGAARCAYCAY CARTTYGAYATHGAYTCNGAYGGNACNGTNAGYCARGARGARGCNAARGARTAYYTNGAR GARAAYGARGARGTNAAYGCNGCNATHTTYACNGARAARATHTGGCCNAAYATHAARGAR ATHTAYAAR---------------------YTNGARAAYAAYGTNAARTCNGAYAGYGAR GTNACNCCNGARGARACNGCNACN---------GARGAYAARGAYCCN---YTNGAYGCN GAYGCNGCN---GAR--------------------------------------------- ---------------GARGAYAARGARCCNCCNTAYAGYGAYGARACNAAYMGNYTNATH GCNGAYGCNGAYYTNGCNMGNTCNCARTTYGAYGAYGCNGARAARAARYTNMGNGAYTCN GARMGNGAYATHAGYGAYATHMGNAARTAYYTNGARATHGAYTTYGGNYTNAAYCARGAR TAYGCNGCNYTNAARGGNCARTGYTTYGARTAYATHGAYMGNGARTAYAARTAYCARYTN TGYCCNTTYGARAARACNACNCARGCNAAYAARAAYGGNGGNATHGARACNTCNYTNGGN ACNTGGGGNAARTGGCAYGGNCCNGARGGNGAYAARTTYGAYTCNATGAARTAYGARAAY GGNCARGGNTGYTGGAAYGGNCCNAGYMGNTCNACNACNGTNAARYTNCAYTGYGGNACN GTNAAYGARGTNACNAGYGTNTCNGARCCNAGYMGNTGYGARTAYCAYTTYGARTTYACN ACNCCNGCNAGYTGYCARGCNCCNYTNCCNGARGAYATHAAYGARACNCAYGAYGARYTN ------------------------------------------------------------ ------------------------------------------------------------ ------GAYTCNNNNNNNNNNNNNGGNTCNAAYACNAAYAARYTNGARATHTCNMGNGTN CARATHGAYGAYCAYACNGGNATHTAYTAYTGYMGNATHTCNMGNGGNGARGARGTNATH TTYACNCARGARGCNGTNYTNCARGTNTCNTCNCCNATH------ACNTAYACNCCNTCN AARTTYACNGCNTCNGAYAARATHGCNYTNATHATGGGNGCNGGNGAYTAYATGAGYGAR MGNYTNYTNGTNGCNCCNAARCAYGAYGTNCARMGNATGTCNACNGTNTTYCARAAYYTN GGNTTYAARGTNGTNTCNYTNYTNAAYYTNTCNMGNAARGARATGATHGCNGCNATHCAY GARTTYAARGAYYTNGTNGAYGARGGNGTNTAYTGYGTNTTYTAYTTYTGYGGNCAYGGN TAYGARGCNGCNGGNCARTGYTTYYTNYTNCCNCCNGAYGCNCCNCARGGNTAYACNCAR GAYCARTGYATHTCNGCNGAYGCNATHYTNTTYAAYGTNYTNYTNCCNMGNAARCCNCAR TTYTGYTGYATGATHYTNGAYATHTGY---MGNYTNMGNYTNCARGGNGTNCCNGARATG YTNMGNACNGCNGTNGCNGAY---------TAYATHATHTGYTAYGCNACNTGYCCNGGN GAYCCNGCNTTYGARCARGARGAYTCNAGYATHYTNGTNMGNCAYYTNAARAAYATHYTN YTNTCNAAYATHGGNATHGARGARACNTTYCARMGNYTNMGNGARCARATHAARCAYGAY CCNGCNYTNAAYGAYGARAAR---------------MGNCARGCNCCNGARATHMGNGCN GTNYTNCCNTAYMGNGGNATHTCNTTYCAYGAYCCNATHAAYTTYACNGGNTAYACNCAR GCNTAYGGNGARMGNCARYTNAARTGGGARGCNGCNCAYGTNYTNCCNCARCCNATHGAY AARATHGTNAAYTTYCCNGGNTTYGAYGTNTTYGTNAARYTNGARTTYCARGCNGAYTTY TCNAAYGCNYTNACNATHTTYACNACNGTNYTNGAYGCNGGNYTNGCNAARTCNTGYAAR GCNCAYGTNAARAARATHCCNATHGAYGTNGCNGARAAYGCNAARGTNCARTGYGTN--- ---------GAYGAYACNTTYCCNAARAGYTCNYTNCARYTNCAYCAYATHCARMGNYTN AARTCNGAYATGCAYGTNATGGTNYTNGTNACNTGYATGGCNGAYGGNACNGTNCAY--- GARGARACNTTYACNGARAAYYTNGGNATGCCNYTNGTNTCNCCNYTNCAYYTNTGGAAR GAYTAYCCNAAYGTNATHMGNTAYCARGARGCNGARGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNTAYGAYGTNGARGARCCNCCNAARMGNYTNATHGAR GAYTAYTGYAAYATHACNACNMGNYTNGAYATGAGYTTYAAYMGNYTNAARACNYTNAAR GGNYTNGARCAYTTYAARTTYYTNAARGARYTNATHYTNGAYAAYAAYAAYYTNGGNGAY TCNGTNAARYTNCCNTCNYTNMGNGARYTNCAYACNYTNACNATGAAYAARAAYMGNYTN AARGAYYTNAGYTCNYTNYTNGAYCARYTNMGNGGNAGYTAYCCNAAYYTNACNTAYYTN AGYYTNYTNGGNAAYCARGCNTGYCCNAAYCARYTNTCNTCNYTNGAYAARGAYGAYGAR GAYTAYCARMGNTAYMGNTAYTTYGTNYTNTAYAARYTNCARAARYTNAARTTYYTNGAY TCNACNCAYGTNACNAGYAARGARYTNGCNGARGCNAARMGNATHGGNCCNTTYATGCAR GTNGTNMGNCCNGTNATHGARGAYGARCCNGARTTYGARCARCCNGTNGARACNGCNGCN GAYACNAARTAYACNCCNYTNCCNACNGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARGAY CCNAGYGAYGAYTCNGAYTCNGAYTCNGGNGGNTTYAAYGAYGARAGYAAYTTYCARCCN ------------AAYGGNCCNAARCCNGGNAARAARACNAARGGNMGNGTNAARATHAAR ATGGARTTYATHGARAAYAARYTNMGNMGNTAYACNACNTTYAGYAARMGNAARACNGGN ATHATGAARAARGCNTAYGARYTNTCNACNYTNACNGGNACNCARGTNATGYTNYTNGTN GCNAGYGARACNGGNCAYGTNTAYACNTTYGCNACNMGNAARYTNCAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATHGCNCCNAAYYTNGGNACNTAYMGNGGNGGNTCNYTNCCNAAY GTNAAYCARATGGCNACNACNCARGGNATHGAYYTNCARGCNACNYTNCARCAYYTNGAY AAYATGAARCARGGNMGNACNAGYATHGAYMGNCCNCAYCCNMGNCARGARMGNCAYMGN CARTCNGTNGGNCCNCAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATHTAYTTYGAYACNCCN GTNGGNGGNGCNCAYCAYCARTGYTCNMGNATGYTNATGATGGAYTGGACNAGYMGNAGY GARAARGTNGTNGTNGAYATHGTNAARAARGCNGARGCNTCNTCNTTYCARGGNATHTTY GTNGAYTCNATGCCNMGNGARATHTGGTTYGAYGAYGGNGTNCAYGTNGCNTTYTCNTCN GCNTGGMGNAGYAGYAARGCNGTNGTNATHGTNAAYACNTCNACNGGNGTNGTNAARMGN YTNTCNAARGAYATHAAYGGNGARAGYYTNTCNGTNYTNCARGTNCAYAARTCNTGYATH YTNATGACNTGYTCNTCNATHTCNAAYCCNCCNTAYYTNTCNYTNGCNYTNYTNTCNGAY GTNCARAAYCCNGARTCNGTNMGNTGGATHAAYCCNGAYGGNAAYCCNGARMGNYTNGAY TGGATHTCNTCNTGGGARGTNMGNTGYCAYAAYCCNTCNAARGAYMGNGCNAGYGCNGCN AAYGGNTTYYTNGAYTAYGARAGYATHYTNTGYYTNCCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGGGNGARAAYAARGAR---TGYGARGCNTTYGTNACNYTNGCN ACNAAYGAYACNTAYAGYYTNGGNTGYYTNGTNYTNGCNAAYTCNYTNMGNMGNGTNAAR ACNACNMGNAARYTNGTNGTNATGGTNACNAGYGGNGTNTCNCCNTCNATGMGNGTNCAR YTNCARCARATHTAYGAYGARATHTTYACNGTNGAYGTNYTNGAYAGYTCNGAYGCNTGY AAYYTNGCNYTNYTNGGNMGNCCNGAYYTNAGYGTNACNTTYACNAARYTNCAYTGYTGG MGNYTNACNCARTAYACNAARTGYGTNTTYYTNGAYGCNGAYACNYTNGTNATHAARAAY GTNGAYGAYYTNTTYAAYMGNGGNGARYTNTCNGCNGCNCCNGAYGCNGGNTGGCCNGAY TGYTTYAAYTCNGGNGTNTTYGTNTTYGTNCCNTCNGARACNACNTAYGCNAAYYTNYTN CARYTNGCNGTNTCNCAYGGNTCNTTYGAYGGNGGNGAYCARGGNYTNYTNAAYYTNTAY TTYAAYTCNTGGGCNACNCARGAYATHGGNACNCAYYTNCCNTTYACNTAYAAYGTNGTN TCNCARGCNTTYTAYAGYTAYYTNCCNGCNTTYMGNCARTTYAARGAYCARGTNAARATH GTNCAYTTYATHGGNGCNGTNAARCCNTGGCAYCAYCCNTAYAGYGTNAGYTCNGGNAAR GTNACNGCNYTNGCNGARACNGGNCAYGAYCARCARTTYYTNCARATHTGGTGGGAYATH TTYATGGAYAARGTNCAYCARGGNYTNGAYCCNCAYGTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNMGNCCNAAYGGNTCNGTNYTNGGN GAYACNTCNTTYGARGAYATHAGYAARGCNGGNAARMGNATHACNGAYTCNGCNTTYGAR TTYYTNAAYACNTAYYTNTCNGAYGAYGAYGGNAAYGARACNGAYATHGARAGYCCNCCN YTNTCNCCNGCNYTNCARTTYAAYTCNCCNTCNGTNGAYTTYYTNTCNGTNYTN------ ------GGNAAYGAYGTNCCNTCNTAYCCNTAYGAYYTNCCNGAYATHAAYATHAAYACN ACNGARTTYGARCARYTNYTNATHCARAGYYTNMGNGAYATHCCNYTNTCNYTNGAYGGN TCNATGGAYTAYGAYGGNGARATHCCNAARGGN---GGNTTYGARYTNCCNGTNCARCAR GAYTTYTTYAAYAARTCNGCNAAYACNGTNGGNCCNAAYTTYGARGCNTTYTTYAAYAGY TTYTCNGTNGGNTGYATH---GARAARCCNCARTAYGGNCCN---CCNACNGAYMGNAGY ACNACNCCNCCNTTYTCNGGNGGNAGYACNCCNCARAGYCARTCNMGNGCNCCNTCNCCN GCNTGGAGYGARAGYAGYGGNAAYATHAGYACNAGYAGYGTNTCNGGNGTNTCNTGYCCN MGNAARATGTCNCARGARAGYGCNACNATHGTNCCNMGNCAYAARMGNCCNTCNCAYMGN MGNGCNGARGTNAARMGNMGNGAYAARATHAARACNTGYYTNGAYGAYATHMGNGCNTGY GTNCCNAGYYTNCARGTNAARGGNAARYTNAGYGARTCNGCNATHYTNATHAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGNAGYYTN TCNCCNCARAARTAYGTNTGGMGNGTNTTY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MGNATHTGYATHGTNMGNGGNGAYAAYTAYTGY GGNYTNMGNAGYACNYTNTTYCARYTNYTNGTNAAYGGNYTNMGNYTNGCNCCNAGYTCN TGGGGNATHATHGGNATHATGGAYCARYTNCAYGCNCAYTTYGAYGAYCCNATGGTNAAR ATGTCNAAYTGGTCNTTYGCNGGNMGNYTNCCNGGNCAYTGYMGNGAYAARYTNGCNTCN YTNTCNAARTGYGCNYTNTCNYTNTAYGCNACNGTNGARGARGTNTGYAAYYTNAAYACN MGNGARGARMGNGARAARMGNACNATHAGYYTNTTYAAYGCNAGYGCNACNTTYGAYYTN GARYTNYTNGARGGNYTNAARGCNATGATGGTNYTNCARYTNATHGCNYTNMGNCARCAR ATGYTNGAYGARGARGARGTNCCNACNTTYGTNCAYYTNYTNTTYGCNMGNGAYACNTCN GARTCNGTNTCNGARTTYATHATHAARCAYYTNAAYTGYGTNGGNGAYACNGGNGGNATG GARCARGTNGARATGTGYYTNYTNGGNTAYACNYTNGGNGTNMGNATHMGNGTNYTN--- ------------------------------------------------------------ ---------------------------------------------------------YTN GCNGGNAGYGTNGAYGGNAARGTNATHTTYGTNGGNYTNCCNGAYGGNYTNGCNGCNTTY GAYGCNGCNACNCARTTYCCNYTNTAYAARTGGGARGARGAYCARGTNGARATHACNTCN ATHAARACNTAYYTNYTNGCNCCNAAYTGYCAYTTYATHACNACNGTNGAYGAYATGGCN ATHGCNMGNYTNTTYYTNTTYGCNTAYGAYCAYATHTTYTTYATHAARGCNYTNAAYGAR AAYAGYCCNGARGGNACNACNAARATHYTNTGYCAYAARTGYGARGCNTCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARGTNMGNTCNGCNCARTGYAAYGTNGTNGARGCNGARCARAAYTTYYTNAAR GTNCARGARGARMGNMGNGGNTTYCARCARGARYTNAGYGAYGTNCARTCNGARGCNMGN TCNGTNGCNATGGARYTNGARAARACNCAYMGNACNGAYCCNTCNTAYATHGARYTNGTN AARAARGARCAYGGNATHYTNTGYACNGARAARGARYTNTCNAGYMGNGTNAARATHYTN GAYAARTCNGARMGNGAYYTNTTYTCNTTYYTNAGYATGMGNGTNMGNGARAGYCAYGAR AARGARMGNGCNMGNGCNGARMGNACNAARTAYTGGTCNATHGTNGGNTCNGTNGTNGGN GCNGTNATHGGNATHACNGGNTCNACNGTNAAYAAYCAYMGNMGNYTNAARGARATGMGN GCNATGGTNCARGAYTGYACNGARACNAGYGCNGARTAYAARGAYATHGCNGAYMGN--- ------------------------YTNACNATHMGNTTYATHTCNAAYATGCARACNGAY AGYMGNTCNCAYGGNTTYAARYTNAARATHYTNTAYGGNAARACNACNAGYGARYTNYTN YTNMGNATHCAYGARGTNMGNAARGARGARGARAARAARGARAARGAYGAYAARACNACN YTNYTNGTNATHYTNGCNTCNAGYYTNYTNGTNYTNATHYTNGTNGTNGTNGTNGCNTTY GTNGTNTAYYTNYTNTAYCAYMGNCAYGCNCCNGCNTAYGCNACNCCNCCNGCNTGYYTN CAYMGNGTNGGNYTNGARTCNAGYTCNACNGGNTCNTCNTTYCCNGCNGAYTTYACNAAR CCNGTNCCNYTNGCNGTNGTNTCNCCNGAYGGNMGNAAYCCNTGGACNAAYAGYGGNAGY CCNTGGGGNAARTGYCCNAAY------CCNGTNCCNTGYTCNYTNGARGAYGTNATGAGY GARCARYTNGCNTCNGARYTNGARACNGARAARATGAAYGARGARAARGARAARYTNAGY GARGCNTCNGARCARAAYCCN------------------------TCNGAYGCNTCNAAY YTNTGYGAYGCNGARYTNGCNGCNAARYTNGCNGCNGARGARGARAGYTAYGAYCCNAAY GAYGARATGATHGCNYTNYTNYTNCARAARCARTTYGAYMGNGARCAYGAYGCNGARYTN ACNAARGTNGARCARAARTAYAAYGGNAAYAGYAARGTNGCNATHTCNTTYGARAAYTAY AARMGNMGNAAYATGCARTCNGARTAYCARAAYGCNGARGARGAYGAYGAYGAYGAYGAR TAYGAYGARGAYATHCCNGARCAYCCNTCNCARACNAARTGGGAYAAYGGNACNCCNACN ATHGGNAGYMGNGGNTAYAGYGGNCARGGNAARAGYATHGTNACNAARCAYGAYAARGTN ATHTGYGGNMGNMGNAAYGCNCARMGNYTNATGCARTTYCCNCCNGARTTYGGNTGYGGN GAYGGNGARGGNATGGAYATGCARYTNCCNAAYAARGTNTAYAAYAARYTNAARCARCAY TCNTAYTCNGARAAYCARAARMGNCAYAARGTNYTNGAYAARAARGAYCAYTCNACNGCN ATHAARGCNGTNGAYGARAARACNMGNATHYTNATHTAYAARATGGTNAAYTCNGARTTY YTNACNGCNGTNGAYGGNGTNGTNAGYGARGGNAARGARGCNGTNGTNTTYAARGCNAAY GGNGGNMGNAARGAYGAYGTNGARGTNCCNAARGAYGTNATHYTNAARGTNTTYAARACN TCNATGAAYGARTTYAARACNMGNYTNAARTAYGTNAGYGGNGAYTAYMGNYTNTCNAAR GAYGCNTTYAARAARTTYAAYCCNMGNAARYTNATGMGNATHTGGGCNGARAARGARTAY YTNAAYYTNAARAARYTNAARMGNAAYGGNATHCCNTGYCCNACNCCNYTNATHYTNAAR AARCAYATHYTNGCNATGACNTGYATHGGNGGNGARAARCCNGCNCCNAARYTNMGNGAR GTNGTNYTNAAYACNGARGAYTTYCARAGYGCNTTYAARCARACNGTNGARYTNATGAAR AAYATGTAYTAYAARTGYAAYATGGTNCAYTCNGAYTTYAGYCCNTAYAAYYTNYTNTGG CAYGAYGGNAARGTNTGGGTNATHGAYGTNGGNCARGCNGTNGAYMGNGAYAAYGTNAGY TCNTCNTCNTTYYTNYTNMGNGAYTGYAARAAYATHTGYGAYTTYTTYMGNCARGCNGGN GTNMGNGGNGTNCCNTCNGCNGARGARYTNTTYAAYCARATHACNAAYTAYTCNTAYACN GGNAARGGNAARGTNTTYGARTCNCARGTNCARMGNTAYGARAARGARGARTAYGCNTTY GAYTAYTTYTTYGARYTNTCNGARTCNTCNMGNGCNCARMGNYTNGARYTNGAYAGYGAR AGYAGYAGYGARGAYGARGAYGAYGGNYTNGARGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CCNYTN CCNAARCARGARAARMGNAARCCNCCNGCNCCNAARCCNCARACNCARTTYCCNGAYTCN GAYCARACNCCNATGGAYGCNGAYGTNGTNATGGTNGTNCAYGCNCAYYTNCAYCCNGAR AAYYTNMGNYTNACNCARCCNATGAARATHGAYGAYMGNAAYGARAARMGNAARAARTTY TGGMGNGARGTNTAYMGNAARACNGARYTNATHTAYTGGMGNAAYATGMGNCCNTTYATG TTYACNGTNCARYTNCCNAARMGNGGNCARGGNGTNAGYYTNYTNGTNCCNTCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CARCARACNGARATHGAYGTN GGNATHACNCARTTYATGGGNTCNAAYGTNGAYCCNTTYAGYGCNGTNATHAARCARMGN TAYTCNGAYTTYATHGTNAAYGARATHGAYTCNGAYGGNAAYATHGTNCAYYTNAARTCN GTNACNTTYAARGAYAARGARAARGARGARGARGARGARGARGARAARATGAGYGCNGCN GCNAGYATHYTNAGYGARGCNGAYMGNGARGTNATHCARAARATGGTNAARGAYMGNAAY AARACNGAYACNCAYAAYATHYTNGCNCCNGARGAYAARGCNYTNMGNACNAARATHCAY YTNGCNGTNAARCARAGYTTYTCNCARYTNGARACNGTNACNGGNGARGAYGAYAARGGN AAYAARGTNATHAARGTNACNTGGMGNAAYGGNAARMGNMGNGAYGCNATHAARGAYGAR TGGCCNAARTCNAARAARTCNTGYMGNTAYGTNMGNTTYGTNYTNTAYAARGARAAYAAR GAYACNATGGAYGCNATHGGNYTNATHGCNAARAAYYTNAARGTNMGNGARAGYATGTTY CARTTYGCNGGNACNAARGAYMGNMGNGCNAARACNACNCARGARGTNACNGCNCAYMGN ATHCAYCCNAARAARYTNGTNGGNYTNAAYAARGTNYTNTGGAAYATGGGNYTNGGNGAY TTYMGNTAYGTNCARCARCCNYTNCARYTNGGNCARYTNTCNGGNAAYCAYTTYACNATH GTNYTNMGNAAYGTNAARGCNAGYAARGAYATHGTNGAYTCNGCNYTNAARTCNYTNAAR GARAARGGNTTYGTNAAYTAYTTYGGNATGCARMGNTTYGGNACNACNTCNATHCCNACN CAYTAYATHGGNAGYACNYTNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGTCNTCNGARYTNCCNATHTTYCCNAAR GCNACNTCNATGTTYYTNCAYAGYGGNAAYATGATHAAYTGGAAYMGNYTNAARMGNAAR CCNAAYYTNTCNTCNTCNGAYGARYTNTGYGARGTNATHAGYGARACNYTNGAYTCNTAY ATHCARTCNGCNGAYAARACNGARYTNCARTAYGTNACNGARATHTAYAARGTNAAYACN GARAGYGTNGARYTNATHGARGARAGYGARMGNGGNGAYATHAARATHACNGTNAARYTN TTYGTNTGYGAYTCNCARCCNACNTCNGTNATHGGNGAYGCNGTNAAYAARGTNYTNAAY GARGTNGGNACNTCNTTYGTNGARACNYTNYTNYTNTCNATHTAYCCNAAYGTNGCNGAR GAYGARGARCCNGAR---CCNGTNAGYYTNTCNACNATHCARGGNTAYTGGCARGCNATG GARGARYTNGTNGCNAARGAYAARGTNYTNTCNYTNGGNATHTGYGAYATGGGNAARGAR GGNYTNGARGCNYTNTAYGAYTGGGCNCARGTNAARCCNTGYGTNAAYCARGTNAAYYTN GARTCNTGYTGYGTNYTNCCNAARGARYTNACNGARTAYGCNAARGCNATHAAYATHCAR YTNYTNACNCAYAAYGAYAGYCCNGTNTTYGTNACNAARGARATHYTNCARGAYAARATH CARTCNGTNGCNACNGARMGNGAYAGYGAYGCNTGGGCNCCNGARTGGGTNGTNMGNTAY TCNGGNATHATHAARTGYMGNGGNATHATHAARATGAARGGNTAYATHTTYCAYGCNAAR MGNGAYAAYMGNAARMGNATHYTNGTNAAYGTNCAYGCNCAYGCNGARYTNMGNATHMGN CARYTNMGNYTNTTYGARGGNATHATHAGYCARTCNCAYCARYTNYTNYTNATHCARAAR AAYGTNATHMGNCCNYTNYTNAARYTNYTNATGGARGTNGCNGARTCNTCNGARATHGAY AAYGGNGARYTNGARTTYAARYTNGTNYTNYTNYTNCAYCARATHTGYATHTGYATHTCN CAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGTTYGGNTCNAARMGNCCNYTNTTYGGNGARGAYCCNATHAAYCARGGN TGGAAYATGAAYTAYGGNGARGTNCARGARAGYGARMGNAARMGNAARMGNAARAGYMGN TGGAAYACNGAYAAYGAYGAYAARACNGTNATHCCNGGNATGCCNACNGTNATHCCNGCN AAYYTNTCNGARACNCARCARMGNCARTAYGTNGTNCARYTNCARATHGARGARATHACN MGNAARYTNMGNACNGGNGARYTNGGNATHCCNTCNAAYCCNGARCARMGNTCNCCNTCN CCNGARCCNATHTAYAAYAGYGARGGNAARMGNATGAAYACNMGNGARTAYMGNACNMGN AARAARYTNGARGARGARMGNCAYMGNYTNATHCARGARGCNATGAARYTNAAYGAYGAY TTYAARCCNCCNAGYGAYTAYAARCCNCCNGTNATHMGNGTNAAYGAYAARGTNATGATH CCNCARGARGARCAYCCNGARATHAAYTTYGTNGGNYTNYTNATHGGNCCNMGNGGNAAY ACNYTNAARACNYTNGARAARGAYACNGGNGCNAARATHATHATHMGNGGNAARGGNTCN GTNAARGAYGGNAARATHGGNMGNAARGAYGGNCARCCNYTNCCNGGNGARGAYGARCCN YTNCAYGCNTAYGTNACNGCNAAYAAYCCNGARAAYGTNAARAARGCNGTNGARCARATH AARGARATHATHAARCARGGNATHGARGTNCCNGARGGNCARAAYGAYYTNMGNMGNCAR CARYTNMGNGARYTNGCNYTNYTNAAYGGNACNYTNMGNGARAAYGAYGGNYTNCARAAR YTNMGNCARATHGCNGARAGYCARACNATHGTNACNAAYACNATHGTNTGYACNATGTGY GGNGGNACNGGNCAYATHGCNCARGAYTGYAARCARAARMGNCCNGGNGAYACNTTYMGN ATGCARCARATGCARAAYCCNGCNGAYMGNGCNAARATGGAYAGYGARTAYATGTCNYTN ATGGCNGARYTNGGNGARGGNCCNTCNCCNCCNAARTCNGARGCNCCNAAYTCNGGNCAR ---------------AAYCARGCNCCNTTYAAYMGNAAYATGYTNGCNAAYCCNCCNCCN AAYCCNATGGCNATGAAYCARCCNTGGCARATGCCNCCN---AAYMGNCCNCCN------ ------------------------------YTNGGNGCNAAYYTNAAYMGNCCNCCN--- ---ATGGGNATGCARTCNCARCARATGAAYCARATGGGNMGNATGCCNATGCCNYTNATG ACNTCNCCNCCNGGNCCNCCN------------------------------------GGN GCNCARTCNTCNAAYTCNATGATGAAYCARCARCARGGNCARCARCCN------ATGGGN AAYATGCARCARCCNCCNCCNCCNCCNCARCARCARCARCARCARTCNATHMGNCCNTGG CAYCAYCCNCCNACNAGYCARCARCARGGNATGATGAAYCCNGGNATGCCNCCN------ ---------------------AAYTCNAGYGCNAGYATGGGNATHCCNCCNCCNCCNTCN TCNATGATGAGYGCNCCNCCNCCNCCNCCNACNAGY---------ACNGGNCAR---CAR GCNCCNCCNCCNTGGATGCARCARCCNCCNCCNCARCCNGCNGGNATHGGN--------- CARCARCCNCCNCCNCCN---CCNCCNTCNACNTCNGCNGCNCCNTGGCARCAR------ ------------------GAY---------AAYATHYTNGTNCARAAYGTNGAYGGNTCN GARYTNACNGTNAAYGGNGAYGGNAAYYTNGCNGCNATHATHATGCCNGGNACNTCNGTN CCNGCNGARCCNCCNCARGAYTGYCCNGCNTGGGCNGCNMGNYTNYTNAARTGYGARAAR ATHGGNGAYTCNTAYMGNGGNTAYGTNGARACNGARGTNGARYTNGAYATHGTNYTNACN YTNCAYAARCARCARACNAAYAGYTTYTGGGGNACNMGNCARTCNCCNAGYTCNGCNAAR TCNTCNACNMGNYTNATGTGGAARTCNCARTAYGTNCCNTTYGAYGGNATHCCNTTYGTN AAYTCNGGNAGYMGNGCNGTNGTNATGGARTGYCARTAYGGNCCNMGNMGNAARGGNGCN AARAARAGYCAYTGYCCNACNGAYCAYAAYGGNTTYAARYTNACNTGYCCNGCNMGNATH TAYGTNAARAARGTNMGNCCNTCNCAYGCNGTNGAYYTNAAYATGGAYAARAARAGYATH MGNGTNGCNATGGAYAARGCNTTYCARGARYTNMGNGARAAYGTNYTNGTNGTNTGGGGN GARGAYMGNTTYTAYGTNCARYTNCCNACNGARGCNGCNCAYGAYTAYCAYGARAGYGAY GARACNGARGGNGARGARTCNGCNGAYAGYMGNAARATGCARGGNGGNMGNATHCAYCCN MGNGTNYTNGARAARATHMGNCARYTNGTNGCNGCNGGNGARACNAARYTNTAYGCNATH MGNAARCAYYTNMGNAARTTYGTNGTNTGYGAYYTNTAYAARGGNTCNMGNCARGCNCCN GARMGNCAYGAYYTNACNGTNTTYCCNACNGTNAAYGAYYTNAARAAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TCNCCNATHTGYTCNMGNAGYCARMGNAARTAYYTNCARACNAGYATH TTYCCNATHATGTCNTCNTCNGTNTCNTCNCCNYTNACNAGYTCNTCNGTNGTNGTNMGN MGNGARAARAARAAYMGNMGNATHYTNGAYMGNCCNAAYAGYATHGCNTTYTCNACNTAY CCNACNTGYGAYYTNATHTCNAARTCNCCNGAYAGYAAYCCNAGYGCNAGYACNTGYAAY CCNGAYGAYGTNAAYGGNGCNATGTCNTTYAAYCAYTAYCARMGNACNTCNTCNYTNAGY CCNGAYATHCCNTAYCAYACNGGNMGNTCNACNTGGGCNAGYTAYTCNGARMGNGARATH TAYCAYCARATHACNGCNGCNATGGARAGYGCNATGYTNMGNACNCARGCNTAYCARCAY TCNCARCAYTCNAAYTGGTCNTCNTCNTCNTCNCARCAYTCNACNTCNTCNMGNAARTCN MGNAGYYTNGAYAAYATHYTNGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MGN AAYGCNAARGARATGATHGGNGGNTGYTGYGTNTGYTCNGAYGARMGNGGNTGGAGYGAR AAYCCNYTNGTNTAYTGYGAYGGNCAYGGNTGYAAYGTNGCNGTNCAYCARGCNTGYTAY GGNATHGTNCARGTNCCNACNGGNCCNTGGTTYTGYAARAARTGYGARTCNCARGARMGN ATHGCNMGNGTNAARTGYGARYTNTGYCCNCARMGNGAYGGNGCNYTNAARMGNACNAAY TCNGGNGGNTGGTGYCAYGTNGTNTGYGCNYTNTAYATHCCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATGCCNGGNGGNMGNMGNATHYTNTCNMGNATHCARTCN AAYGGNCCNTAYTCNTCNACNGGNAARAAYTCNGGNGGNAAYGGNAGYCAYGGNAAYGAY GARAARGAYGGNAAYGTNGTNCCNYTNGCNTCNATGGTNGTNYTNCCNAARCAYAGYCAR YTNCCNGAYATHCCNGGNGAYGGNAAYYTNTAYTTYGARTGYATGYTNTTYGTNTTYGGN ATHATHACNATGTGYYTNCARTAYATHAAYYTNTAYAARACNGTNTGGTGGYTNCCNCAR TCNCAYGCNCARTAYGCNYTNAAYTTYTAYYTNATHGAYTTYAAYYTNGCNGTNYTNATH TGYATHGTNYTNGTNATHMGNTTYYTNATHTGYTTYTCNCARGARGTNCAYAAYAGYMGN YTNYTNTAYTGGCCNYTNGTNTGYYTNAARAGYGTNATGATHAGYTTYTCNATHGTNGTN TTYGCNTAYACNGGNTAYAARGTNGTNATGGGNCAYGGNATHGTNACNAGYYTNTTYYTN TGYTAYCCNGCNGTNATHTAYYTNGTNYTNTTYGGNGTNGCNATHAARCCNATHTAYCAR AARCAYCARGCNTGGCCNMGNCCNGCNTAYACNATGGAYMGNCCNGCNGGNCCNATHMGN ATGAARATGAARGAYGAYGCNCCNYTNTGYCAYACNTGYACNYTNACNCCNGARATHGTN MGNGARGARGTNGAYATHYTNAARAARGAYTTYAAYAGYMGNYTNAARCARATHYTNTTY AAYTCNYTNACNACNTCNTTYTAYGCNACNGGNGTNCCNGTNTGGTTYTCNCAR---AAY ACNYTNTAYTAYGAYTCNTGGTGGATGTGGCARCAYGTNTCNYTNACNTGGYTNAGYGCN YTNYTNATGYTNACNGCNCAYTTYYTNCCNCCNCAYTAYYTNCAYYTNYTNCAYAARAGY GCNMGNCAYYTNGGNMGNTGGCARMGNATGGARGCNMGNCAYGCNCAYGTNCCNTAYAAY GCNTGGTCNGARYTNCARGTNTGGCCNCARGGNGCNYTNGTNAARCAYGTNMGNGGNYTN TTYAARGCNGARGGNATHAAYATHACNGCNGARCCNGGNAAYAAYYTNCAYAGYMGNTTY TTYYTNYTNTTYCAYCARCCNATGMGNGTNATGAAYTGGYTNGTNTTYYTNACNTGYYTN GTNATGGCNTAYCARGGNTTYMGNYTNYTNCARAGYTCNGARTGGAGYCAYATHATHTCN YTNGCNYTNYTNATGTTYTGYAAYTTYTAYACNYTNTTYAARYTNATGMGNGAYTGGTTY ATHATGGCNAARGTNTAYAARGAYAAYGAYTAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CAYMGNTGGATGGCNATHATHYTN GGNAGYGARACNCARCAYYTNCCNATHGGNGARCARATHAARAAYGCNTTYATHATHMGN GARCAYATHGARACNGCNATHAARTAYMGNCCNAAYGAYCCNYTNYTNTAYCAYATGATG GGNMGNTGGTGYTAYAGYGCNTAYATGYTNACNTGGATGGARMGNCARYTNGCNTCNGCN YTNTTYGCNACNCCNCCNACNTCNACNYTNGARGARGCNYTNTTYAAYTTYGARAARGCN GARGARYTNAARCCNYTNTCNTCNATHCCNAAYCARYTNTAYYTNGCNAARTCNTTYATH GCNAARGGNGAYTAYAARATHGCNGTNAARCAYYTNGARATGGGNATGAARATHGARGCN AARYTNTGGGAYGAYAARGCNGCNCARGARGARGTNAARAARGAYYTNAARTAYTAYAAR TCNTAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARATHGARATHCARAGYACNTAYGCNGAYGGNTTYTCNYTN TCNGARAAYYTNTTYATHTAYGAYTGGTTYCAYGGNAARATHAGYMGNCARGARGGNGAR AAYMGNYTNCARAARTAYGGNAARAARGGNGCNTTYYTNATHMGNGARAGYTCNAARACN AAY---------AAYCCNTAYACNYTNGTNATH--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNATHCAYTTYATHAGYTAYTCNACNGARGTNTTY CARGGNAARCARACNTAYAARYTNTCNCARCARGCNTGGYTNATHGCNGAYYTNAARGTN GCNACNTCNAAYMGNAARAARACNCCNTGGATHATHGCNTTYGGNAAYGCNCCNATGTAY TGYACNAGYCARGARCCNTCNYTNGCNTGYAAYAARCARGTNAGYAAYGGNGCNAARGAR YTNGARGAYYTNATGTAYAARTAYGGNGTNGAYYTNATHYTNTCNTCNTCNCCNAAYGGN AAYACNGTNTCNTAYCCNATGTAYAARGGNGTNAARGTNGGNGAYAAYCAYACNTCNCCN YTNGCNCCNATHCAYGTNAAYATGGCNGCNGCNACNAARTGGACNGAYAGYTAYAAY--- ---TCNTCNGARGARGAYTGGGTNTGYTTYCARGGNGAYGAYAARTCNCCNYTNACNTAY GGNMGNYTNCARGTNCAYAAYACNAGYTGYYTNCARTTYGARYTNGTNGCNTTYGARGGN GAYCAYGTNYTNCAYTCNTTYYTNATHGAYCARCCNATHCAYMGNGGNTTYTCNAARGAY CARYTNTCNGTNAAYATHAGYCAYGARATHGAYCARCARATHAARYTNGCNGGNGGNGAY CCNAAYAAYCCNAAYATHAAYAARACNACNGTNAAYAARATHACNGARAARATHCARGAR TAYYTNAARGGNGAYAAYMGNAAYACNATHATHATHGGNACNAGYGTNGCNGGNGCNATH YTNYTNYTNYTNGTNAGYGTNYTNGTNATGMGNMGNGTNTGYMGNGGNMGNMGNMGNCAY TCNGCNMGNMGNTGGGARACNATGGAYATHAAYTAYGGNAARAARTAYTAYAAYAARGCN CCNGAYAARGAYGAYYTNGAYCARGAYTTYGARATHGAYATGACNGARACNACNCARTCN MGNAARYTNYTNTCNGAYGAYAAYATHTAYTCNTCNTCNGGN---GCNYTNCCNGAYTTY YTNTCNGAYGGNCCNYTNYTN------GGNGARAARCAYGTNTCNTAYCAYCCNAGYGAR AAYGGNMGNMGNGARGAY---------GAYYTNATGAAYCARATHCARATHYTNCARGAR GARAAYAARMGNYTNMGNAARGAYYTNTCNCARYTNCARCARAAYTGYGAYAAYAARAAY CARMGNATHAGYCARATGAARACNGAYYTNGARMGNCARAARAARAARGARGCNGARGAR ACNGCNGTNATGGARAARGCNGTNYTNCARGTNGARGARAAYYTNGTNGTNACNACNCAR MGNGCNGTNCARGCNGARGCNTCNGCNACNAARYTNAARCARGARGTNAARTCNYTNCAR AGYCARYTNAARAGYYTNTCNGCNGARAAYGARACNTAYMGNAGYGGNGAYAGYGGNYTN TCNGAYATHMGNGARMGNACNAARTAYACNTCNGAYCARYTNAARATGGCNGCNGARYTN GCNGARAARAAYYTNAARGAYYTNYTNYTNGGNGTNGAY--------------------- ------------------------------------------GTNTTYCARAAYTGGAAR GTNCCNGARMGNYTNGTNCCNCARCARGARGTNAAYCARGAYGAYCARGARGCNYTNMGN GCNGTNATHACNGGNAARMGNGCNAARGGNCARAGYMGNCCNGARYTNYTNMGN------ ---------------------------------------GAYGTNTAYTGYATHMGNGCN YTNGTNMGNTGYTGYMGNAAYGARCARTCNCARGCNYTNAAYGAYYTNGAYTAYGCNYTN ACNYTNAAYCCNAGYCAYGTNAGYTGYYTNGTNGTNMGNGGNGCNYTNACNMGNCCNCAY TCNCCNCARTAYCCNGGNGAYYTNCCNMGNCCNAAYAARTAYYTNMGNAARGCNGARMGN YTNAGYCCNGAYTCNCARTCNTAYTTYAAYGTNAAYAGYTTYAAYCAYCCNTGYATHCAR GAYTTYTAYGAYMGNATGYTNTTYACNYTNYTNGTNCCNCAYACNATHACNGARATHAAY YTNACNCCNGAYAARCCNAGYAARAARCARATGGAYTCNAGYCCNGARMGNTTYMGNAGY GARTCNTCN------------------------TCNGCNMGNTCNGCNMGNTCNCCNACN GARAARTCNGAYCCNTTYMGNTGYGGNACNCCNTGYGTNGCNGARAAYMGNATGTCNACN MGNMGNMGNYTNGAYTAYGGNGARGCNYTNMGNAARCAYAAYTCNMGNCCNAARACNGCN TCNGARTAYATGGCNGTNYTNGARMGNGARMGNATHAARMGN------ACNACNCCNGCN TCNACNCARAAYCAYCARTGYCCNTCNACNACN---------GGNCARTCNTGGTCNAAR CARTCNTCNAGYAGYMGNGGNYTNTCNGGNACNAARACNACNACNTCN------------ TTYGTNTTYGARACNCCNAGYAAYTAYGAYATHCCNGTNTTYCARCCNGTNAAYATHGCN GARGCNCCNMGNATGTAYTAYMGNCCNTGGMGNGGNGAYAARYTNCCNATHGCNGARGTN CCNCAYCCNAARCCNTCNCCNGCNTTYTAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GCNYTNCCNGAYAAYACNMGNTTYAGYYTNGTNGAYTTY CCNYTNCAYYTNCCNYTNGARYTNYTNGGNGTNGARAARTGYYTNAGYGCNYTNACNGCN ATHATGYTNGARCAYAARGTNATHYTNCARTCNMGNGAYTAYAAYTCNYTNTCNATGTCN GTNATGGCNTTYGTNTCNATGYTNTAYCCNYTNGARTAYATGTTYCCNGTNATHCCNYTN YTNCCNACNTGYATGGCNTCNGCNGARCARYTNYTNATGGCNCCNACN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGGGNCARTAYACNTCNMGN CARGAYATHATHCAYAARGARATHAGYGAYYTNAARATGMGNAAYTGGGTNTGYGCNAAY ATGGCNGTNMGNGARTCNTCNAARGCNGTNGCNATHTCNYTNCAYGGNAARATHTCNMGN YTNCAYAARGARATGGTNAARGCNGTNGGNAAR---GGNGTNTGYACNAARAAYTGYAGY AARAARGARTCNGAYTGGTGYGCNGTNTGYGARMGNTGGTCNAGYGARATHGTNGCNATH TGYGARCCNAGYTAYMGNTCNMGNATHAAYTGGTCNMGNYTNAAYTCNTCNCARTGGCCN GTNAAYCCNTAYGARGTNGCNMGNTCNYTNATHCCNAARGCNCAYMGNYTNTAYTAYAAR TGYTCNGARTTYCAYGARGAYTTYMGNTTYAGYYTNAGYTTYATHGARAAYTGYGTNGAR ATHCCNGTNTCNAARTCNYTNTGYGARCARYTNTGGCARTTYMGNAGYMGNYTNAARMGN AARAAYGGNACNATGMGNATGMGNAGYGGNGAYYTNGARGAYGGNATHGCNYTNATGATH TCNYTNGTNTCNYTNCCNTCNYTNACNGTNAAYYTNCARACNGTNGAYMGNYTNCARACN YTNACNATGGAYAGYGAYGARGARAAYCARAGYTGYGCNATHATG--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGNAARGCNGCNMGNAGYGCNTTYTCNAGYGCNTGGAGYTCNCCNCCN TCNTCNCCNCCNGTNTCNCCNTCNAGYTCNATHGCNCARATHACNCCNGGNGGNACNATH AAYYTNGTNYTNTCNGGNGTNGTNAGYCCNAARTCNCCNACNAAYCCNGGNGCNTTYACN ATHACNCCNCCNACNGARCCNCARTCNTCNTCNCCNTCNCCNGCNYTNTCNYTNACNTCN TCNAAYAARTCNGAYACNCCNATHAARCARAARAARATHCCNCCNCCNCCNCCNCCNMGN MGNGGNAGYMGNCCNACNTCNACNAAYYTNACNTCNATHAAYGGNGTNGARCARCCNATH GAYCARAARCARTCNGAYGARAGYGCNCCNCCNCARTTYGTNGGNGGNATHYTNGGNCAR CAYAARYTNTCNGGNGGNCCNYTNTCNTCNACNCCNAARCARGCNTCNCARCARAARGCN YTNTCNACNTTYGARMGNGAYATHGCNTCNGGNATHTAYGCNAAYATGAAYMGNCCNGAY YTNCARAAYCARAGYTTYTCNCCNAARCARATGATHGAYMGNGCN--------------- AGYCCNAARAAYAGYMGNTTYMGNAAYGTNCCNACNCCNYTNGTNGCNACNTCNTGYYTN GAYMGNAAYGARMGNGGNAGYAGYAGYGARAGYAAYAGYAGYAGYAGYGCNAGYAGYATG GGNTCNCARCARTCNGTNGCNGGNGTNGCNMGNTCNGCNTCNAAYATGMGNAAYAAYAAY AARCCNAARCCNGARCCNCCNAARMGNCAYTCNAGYYTNYTNGGNMGNGAYGAYAARCCN ACNAARACNGARAAYGGN---GAYMGNYTNTAYAARYTNAARGCNGGNYTNTTYYTNACN ACNGTNACNGGNTGYTCNGCNYTNGCNGGNTTYGGNYTNACNYTNGGNATGGCNAARAAR ACNGAYCCNMGNCAYTTYGCNAARGGNGTNATHGGNTCNMGNGARYTNCCNGARAGYGGN GCNGCNYTNGCNACNAARGCNYTNGGNMGNGCNACNYTNTAYTCNGTNACNGGNTTYGGN YTNTTYTGYTTYGCNGTNTGGAARATGATGGGNGTNAARAAYATGGTNGARTTYMGNGAR AARGTNGGNAAYGCNYTNCCNMGNYTNAARMGNACNGARAGYACNGGNMGNAAYGARTTY GCNACNATHMGNGAYYTNTTYAAYTAYATHATHGAYGARGAYAARAARGCNAARGTNGCN AAR------------GARGARGARTGYGARTAYTTYAARCARMGNTAYAAYAGYYTNAAR ATHGTNYTNGARGAYTTYCARAAYCARYTNACNTTYTAYAARAAYMGNTGYYTNGGNGTN GAYACNATHGCNYTNGCNYTNAARGARTCNAARCARGARAAYATHAARYTNTCNAARCAY ATHAARGCNATHGARACNTCNATHTCNATHYTNCARAARMGNYTNGARAARCAYGGNYTN TCNAAYAGYGTNTAYACNCARGARACNGARYTNTTYGTNCCNGGNGCNTCNAARCARACN YTNGAYAAYYTNGCNAARGARACNGCNMGNYTNMGNACNYTNYTNAARCARGARAGYGGN CAYYTNACNAARAARTCNTCNGAYGARATHGARGGNATGAARACNGCNYTNGARGAYGCN CARACNGARAAYGARCARYTNAARAAYAARATHAARGAYATGGARGGNTTYAARYTNAAY YTNGTNGARGARTCNGARGARGCNATHAARAARYTNACNGARAAYCARGARYTNMGNACN AARTTYGAYTTYATHGARCARAARGARGARAARGGNGGNATGYTNYTNGCNGGNTCNGTN CARGARYTNAARGARYTNYTNAARMGNACNGTNCARAARTGYAAYATGYTNAAYGAYAAY YTNCCNGTNAGY---ATHMGNGAYGARCAYCARCAYGCNGAYGGNGARACNAAYGCNAAR GAYTCNCARGTNAGYCARGARGARTAYGARAARYTNCARGCNAARYTNGARGGNGCNGTN AAYATGAAYCARCARTGGCARAARTAYAGYAARGARMGNGARAARCARATHCARYTNYTN AARGAYCARATHCARGARCARCCNGAYCCNCAYCAYCARYTNACNGCNTCNGTNCARGAR GCNMGNATHYTNAAYCARMGNATGYTNCARYTNAARAGYGARYTNGARGTNAARGAYGGN GARATHGTNACNYTNAAYAARAAYATHAARTCNYTNAGYAAY---CARYTNGARGAYGCN AARAARYTNCARCARTCNCARCAYGAYACNAGYACNNNNNNNNNNYTNMGNCARCARATH CARGTNTGYACNGARGAYTTYAAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TTYYTNMGNCAR GCNGARYTNGAYCAYTAYGCNYTNTAYAGYGCNYTNTCNTTYYTNAARAARTGYGGNTGY GGNAAYYTNYTNYTNMGNTAYGTNAARYTNGAYGCNGGNCCNGARACNAARGCNGTNYTN TCNGTNYTNGARAAYTTYATHGCNTCNACNAARCARATGYTNAGYAGYATHGARTGYCAY AGYTGY---------CARTAYGAYAARTGYGGNGAYAAYTAYGAYATHCARMGNTAYGAR GGN------AAYYTNGGNGAYTGYGGNGARGGNATGTAYTGYGTNAARTAYAARACNATH GTNTGGATHCARGAYTCNGGNGARATHAARGGNAAYYTNMGNGARTCNCAYGTNGTNACN MGNAGYTGYGARTCNAARAARGGNCARAARGARGGNTGYATHGGNTGGCARAAYAAYGGN GGNGTNACNYTNAARTGYTGGTGYGGNACNGAYGGNTGYAAYAGYGGNCCNTCNGGNMGN CCNGTNACNYTN------ATGAAYAAYMGNGGNGGNYTNCCNGTNAARAAYATHGTNACN GCNATHTTYATHATHYTNTCNGTNTAYYTNYTNTAYATHTAYAAYGTNTCNCARAAYMGN YTNCAYGAYGCNGARATGACNGGNTCNMGNTAYMGNMGNGARGCNGARGAYAARACNAAY GARATHCARGGNYTNGTNGCNGCNAARGARGARTAYCARGAYMGNTGYGARAAYCARAAR MGNGARTTYAAYAAYMGNYTNAARTCNATHAAYCARAARCAYAGYYTNYTNCARAGYCAR AAYACNGARATHGARGCNGAYTTYATGAARYTNAARCARGAYATGGARAAYYTNMGNGCN GARCAYATGCARACNGARAGYCARCAYGCNCARGARTAYCARACNYTNAARCARACNAAR GARAARGARATHTCNGAYATHACNGARCARYTNACNACNYTNAARCARCARAAYGARCAR YTNMGNACNTCNGTNACNGARYTNCARGGNAARYTNCAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------TAYCCNACNTGGGGNACNYTNATHCCNGCNTCNAGYYTNATHGGNGCN ATHGCNGCNCCNATGTGGACNTCNCARGGNYTNTAYATHACNTCNTTYGGNGARGARTAY GCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATHCCNCCNYTNATGYTNGAYYTN ATHGGNMGNCCNATGATHCCNATGATGYTNGGNGAYATHACNYTNCAYAGYATGGGNGAR ATHGTNAGYGAYMGNCCNAGYTTYCAYTGYCARGARGCNATHTAYCCNGCNGGNTAYTGY ATHACNMGNGTNTTYGTNAGYYTNCARCCNCCNGAYACNMGNTGYYTNTAYACNTGYAAR ATHTCNGARGGNGARGAYGARCCNCARTTYGARATHTCNCCNGARGAYCAYTCNGAYGTN ATHTTYAARGCNACNACNCCNGGNGARTGYCAYMGNYTNYTNYTNMGNTCNATHAAYAAY GCNMGNTCN---GARATHGTNCCNACNTCNACNAAYGGNYTNGARTTYTTYGGNYTNACN CAYGCNGTNYTNCARAAYYTNATHCARTCNATHCCNGGNGCNMGNAARTGYTCNAARTAY AARTGGGTNAARTTYGARATHGAYAARACNCARACNAAYGCNAAYTTYGTNGTNGGNAAR AAYGAYCCNTCNATHAGYTTYGARGCNTTY------------------------------ ------------------------------------------------------------ ------------ATGAAYTTYCAYGTNGARAAYGCNYTNGTNTCNGGNGGNMGNYTNGGN AARATHACNCARGTNATHCARGGNAARGCNGTNGCNYTNGARACNCCNATGTGYACNYTN TTYACNAARGGNGGNAGYGCNCCNTAYYTNGGNATHAGYATGYTNGAYMGNATHAARCAY GCNCCNGARYTNGCNACNATGAGYATHAAYTCNTTYGTNGARCAYGTNGARAGYATHAAR GGNAGYGGNAARAARYTNGCNGAYTTYACNTCNATGAARAAYAARYTNGTNTTYTCNACN YTNCAYGAYGCNAGYYTNCCNGTNACNACNGGNAARAAYGARAARACNGGNGTNGCNGTN TGGGGNAARGGNGGNAARGCNATGYTNAAYCCNGGNYTNTAYATGCARATGCARGARACN ATGCARGCNGAYTGGGTNATGGCNYTNAGYGAYGGNGAYACNGAYATHACNAGYACNGAR AARMGNAAYGGNAARGCNGTNGAYMGNACNYTNGAYTTYYTNGAYGARATGGTNTCNGCN TGGAARAARAGYGARGTNYTNAARAGYTCNAGYYTNYTNGGNGTNGTNGTNGGNGGNTTY AGYGARMGNCARMGNGARMGNTCNGCNATHGARACNGCNACNMGNCCNGTNCAYGGNTTY GTNYTNGAYGGNTTYCARAARGGNCAYATHGARAARAAYYTNTTYGAYGARAAYTCNTTY GCNACNATHYTNTCNAARACNGTNGTNCAYYTNCCNGARGAYAARCCNMGNATHATGGAR ACNCCNTGGTCNCCNYTNCARGTNATHCARGCNNNNAARYTNGGNGTNGAYGTNTTYTCN AGYGCNTAYCCNCAYACNYTNACNGARAARGGNYTNGCNATGATGGAYGAYTTYACNYTN CCNYTNACNTCNTCNATHCARAAYYTNGARGTNGARGGNAGYACNGAR------CCNGAY CAYGGNACNGTNATHAAYYTNAAYGARAARMGNTAYTAYGARGAYTTYGGNCCNGTNYTN GAYGGNTGYAARTGYTAYACNTGYTCNAAYTTYACNMGNTCNTAYATHCAYCAYYTNYTN AAYACNTCNGARYTNYTNTCNTAYGTNYTNYTNACNATHCAYAAYTTYGARMGNTAYTTY YTNTTYTTYGARACNYTNMGNGARACNATHAARAAYAAYMGNYTNGARGARYTNGARGAY AARYTNCAYAARCARGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TTYMGNTAYAGY YTNATHGARATGCAYGAYTTYGTNATHAARAGYAAYGARTAYYTNACNCARTTYTAYTCN ATHYTNAARTGGGAYTCNCCNYTNCCNTCNTTYATHTAYCAYACNGARGTNTGYGTNTTY YTNATHTGYYTNGTNATGTGYCCNGCNMGNTGGAAYTGYTTYYTNTTYATHAAYTGGTTY TTYYTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TAYCAYTAYACNCCNACN GCNGGNATHMGNACNGAYTTYAARMGNYTNATGAAYGAYTTYATHTCNGCNAARACNGTN MGNTTYGARTGYTTYAGYGARYTNTGGMGNAAYAARAAYTTYGGNYTNYTNTGYGCNGGN MGNTAYTCNGARMGNGARACNMGNGARTTYYTNGARMGNGCNTTYYTNAAYGCNGTNGAR TTYTTYYTNCCNCCNTAYCARTTYCARGTNMGNGTNGGNGGNYTNTAYYTNYTNTAYGGN ATHTTYATGACNCARCCNATHGCNCCNAARGTNAARGTNMGNYTNACNGTNGARCARTGG MGNGARACNGTNYTNTTYTAYCARGARGCNAAYCARCARAGYCAYYTNGAYGTNGTNTAY GTNTTYAAYAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARCAYAARAARACNAARCARGGNAGYATHAGYTTYGAYGTNATHYTNAARCCN GCNGCNGTNGARTCNCCNMGNYTNTCNYTNCCNATHTCNCCNMGNGAYAAYAARCARAAR GARYTNTCNGARGARAARATHGCNATGAARYTNAARAARGCNGARCARMGNMGNAGYYTN ATHGARCARGARAARATGGARCARYTNGCNAARGARMGNCARAARGCNATHGARGTNATH ACNAARGCNCARTCNGARAGYYTNGARTTYTCNAARAARACNGARCARAARYTNMGNMGN TCNATGGARATHMGNMGNGARAAYMGNGARACNCARATHMGNGCNYTNCARGARMGNYTN MGNGARCAYTCNGTNMGNGTNCAYGAYGTNCARAAYACNGGNYTNGARATGGTNAARGAR TTYGARGCNAARGCNGARCARAARYTNAAYCARAARATGGARACNTAYGARGARAAYMGN MGNAGYCARYTNTGYTCNATGYTNCARAARYTNCARGARCAYGCNAAYCAYATHAAYGAR GTNTGYACNGCNAGYGAYTGYMGNAAYGCNAAYACNGAYGARYTNCARGARCARYTNGTN YTNAARATGGARAAYGCNYTNAARAAYMGNGARGARCARYTNMGNATHATHCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TCNTCNCARTAYAAYTGY GGNGGNTGGGCNGCNYTNCARGTNGTNGGNGARCCNAARGTNTAYCCNMGNTAYGGNGAY ATHGARGGNGCNTGGGCNCARAARMGNTGYGAYMGNGGNGARTTYATHGARGTNGARTTY GARYTNCCNGTNMGNCCNTCNAGYGTNCAYATHTAYGARACNTAYAAYTCNGGNGCNGTN GTNAARATHAARGGNAARCAYGGNACNGARTCNTGGTCNGTNYTNTGG------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNYTNCARGARMGNGGNGAYMGNYTNMGNTAYYTNATHCAYAARYTNTGYCARAARGAY CCNCAYCARYTNTTYYTNMGNYTNGARTCNCARGTNMGNGARATGATGATHGARATHAAR ACNAAYYTNYTNCARAARYTNAAYGAYAAYGGNGTNCAYAAYCCNGARYTNGCNYTNGAY TTYACNAGYACNYTNYTNCAYCAYTAYGAYYTNATHACNAARAARGGNCAYATHYTNGCN CARTAYYTNGGNGGNYTNACNGAYCAYYTNAARCARTTYCARGTNACNTGGGARYTNYTN AAYAARCAYYTNTTYCAYTCNATHGCNCAYAAYGAYCCNGCNATHAGYTCNGTNGGNCCN ACNATHYTNGARCARYTNMGNCARGGNTCNYTNCARTAYGARAARTCNMGNGARGAYCCN TTYTGYAGYGTNMGNAARMGNYTNYTNAARTTYCARGARGARATGTCNGTNGTNGTNGTN GTNTGGMGNGAYTGYCARCARYTNATHGARAAYTAYTGYCARGARGARTTYACNATHACN CARAARCARGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGGGGNGCNATGAARTCN TCNMGNACNCARGCNATGCCNAARCAYTCNYTNTTYGGNACNGCNYTNGARAGYGTNGAY MGNGAYCARYTNAARGAYATHGARGGNMGNTAYATHCCNGARGGNGTNGTNAARGARACN CCNAAYMGNTAYCCNYTNCCNTCNTAYATHAARGAYGTNATHCCNGGNMGNGARAAYGTN CARACNTCNCARMGNAARYTNGCNACNCARAARGAYGTNYTNTCNCARYTNGAYAAYGAR YTNAARACNAARCAYAAYAARGCNTTYACNTTYAARGCNGAYAGYAARTCNGCNTCN--- AGYCAYMGNACNGTNCAYTCNAAYMGNCCNAGYTGGYTNACNGARAARGAYYTNGARCAY TCNAARGAYATHAAYATHYTNGGNYTNAAYCARCAYGGNAGYTAYAAYMGNGAYMGNTAY GGNAARAARCCNCARGTNCAYGAYTAYAGYYTNATHGGNGAYYTNYTNGCNCCNAARATG GARTTYAAYTCNGCNMGNAGYGCNGTNAARGAYYTNGGNACNAARACNAAYTCNAARGGN AGY---GTNGTNTGGGGNCCNGGNMGNAAYYTNCCNMGNGARYTNATHGAR---ATHCAR CARAARAARCARAARAARYTNGCNAARAGYGTNATHGAYYTNCCNCCNAAYATHMGNCAY YTNTTYGGNAGYMGNATHTGYGAYTCNYTNYTNTCNGAYCAYACNATHGTNTCNYTNGCN YTNGARMGNCARAARTCNAARATGGGNCCNCCNMGNCCNTCNAARAARGARAAYGTNATH GCNYTNCCNGTNGAYYTNAARAAYACNTAYGARAGYYTNGGNCAYACNACNMGNCAYAAY GTNTGYCCNGGNGTNAGYTCNGGNCARYTNATHAGYMGNACNAARGAYGARTTYAAYGAY GARGTNCAYAARMGNMGNGTNCCNAAYACNGAYGARTAYMGNTAYCARMGNGAYGARYTN AGYACNATHTGGGTNGARCARGAYGTNYTNMGNAARMGNATGGARCAYAARTGGAARCAY TAYTTYAARTCNAARCCNAARTCNCARCARAARCCN------------------------ ---------AARCARAARGTNACNAARGARTCNACNCCNCCNCCNGTNGAYGAYGAYATG AAYATHGTNTTYGTNACNCCNCCNYTNACN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GAYGTNCCNATHGTNATHAGYTTYAGYTGYAARYTNTGYAAYYTNGARYTN GAYTGYCAYTAYATHGGNACNAARCCNCCNTTYGCNAARAGYATHGTNYTNCAYGARGAY TGYTAYGTNATGAARGAYCCNTTYTCNTCNGCNGGNMGNTTYGTNACNGTNGGNGGNMGN TGYTCNCARTGYAARCARACNGTNTGYATGGCNTCNACNTGYAGYGTNTTYTAYACNAGY MGNTTYTGYATGAARTGYGCNGGNGAYGARGTNGAYGARTTYCCNGTNGARYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TTYGARYTNTTYCAR GARGARYTNCARGTNYTNMGNCAYGCNTTYCCNAAYCARACNAARMGNTTYTGGAAYACN ATHTCNGCNTCNGCNMGNCARGTNTTYTAYCCNMGNGAYCCNTGYTTYCCNAGYGTNATH YTNATHGCNTCNCAYGCNAARCAYAARAGYYTNAAYTCNTGYYTNGCNAARAARGTNGCN ACNGTNTTYTCNAAYTCNCARGGNACNCARTCNACNTCNYTNGAYACNGAYGTNGARGAY ATGCARCAYYTNCARCCNTCNCARCARAARGARTCNYTNGAYGARACNYTNAAYYTNGCN TTYACNAARGCNGGNAARAARTCNATGGTNATHAGYAAYGTNCAYGCNYTNGCNCCNGAR GCNGCNYTNYTNYTNCAYGGNTTYTGYGAYGGNGAYAAYGCNCCNTTYMGNGAYGTNATG ATHGTNYTNACNTTYGTNGTN---------GAYGAYTCNATHGARTTYMGNTCNGTNAAR CARGTNGARACNACNYTNACNCAYATHTGGCARCAYGGNYTNCAYATHGAYAARYTNGCN GCNYTNATGAGYMGNATHGCNAAYAAYCCNGTNGTNGTNATGGGNGARCARGAYGCNGTN GARMGNAAYATGTGYATGGCNACNAARACNGARAARTGGYTNTGYYTNGARYTNGGNAAR YTNGGNATHGAYTCNACNGARGARAGYGCNMGNTAYATHYTNTCNATGGARAGYAGYAAY GAYYTNGARGARTAYATGYTNGARYTNYTNGAYGGNTCNAAYCCNAARGTNMGNTTYTTY ATHCARGARYTNAARGAYMGNTTYTCNGTNAARGCNAARAAYAGYAAYGTNCAYGCNTAY MGNAARGAYAARCCNGTNGARCCNTGGGARGARAARTCNAARAARAARAAYAARTCNACN TCNAAYCARAGYAAYTTYAAYACNAARAAYAARCARGTNTCNAAYGGNAAYAAYTCNTCN AAYGTNAARGGNAARAARGAYYTNTCNATGAAYAAYGAYAAYGTNTCNCARCAY------ TCNGGNGARATHGGNATHGGNGCNAARAARAARACNAARTAYGTNCCNYTNTAYAGYAAR GARGGNCARGARAARTCNGTNGTNCARYTNCCNGGNMGNCAYMGNTGYGAYTGYCARGCN TCNAARCAYAARYTNATHAAYAAYTGYATGCARTGYGGNMGNATHGTNTGYGCNCARGAR GGNTCNGGNCCNTGYGTNTTYTGYGGNACNYTNGTNTGYAGYCCNGARGARATGGAYATH YTNGARMGNGGNTCNMGNAARGCNGAYMGNYTNMGNGARCARYTNATGCAR---GGNGGN TGYAARACNYTNAAYGGNMGNGARGCNGGNAARTCNYTNYTNCCNATHGGNTTYAGYGGN CARTCNAARGARGAYGARGARAARGCNYTNAARCAYMGNGAYAARYTNYTNGAYTAYGAY MGNACNAGYGTNMGNMGNACNCARGTNATHGAYGAYGARTGYGAYTAYTAYGCNACNGAY TCNAAYMGNTGGYTNAARAARGARGARMGNGAYAARYTNMGNAARMGNGARGARGARYTN MGNGARTCNMGNTTYGGNTCNMGNMGNGAYMGNAARATHACNTTYGAYATHGCNGGNMGN AAYATHMGNGTNYTNGAYGCNGARGARGAYACNGCNAARACNATGTAYAAYAARGARGAY TCNGTNATHCARGAYGTNCAYTAYGGNAARTCNGCNTCNAAYAAYACNGGNCARTCNGGN YTNGTNAAYCCNTCNTTYCAYTTYGARCCNAARTTYYTNYTNGAR---CARGARGCNGTN GARTGGGGNCCNAGYCARTCNMGNCCNGTNTCNAAYGAYCAYAAYCCNCARGCNATGTCN AARMGNATHCARGAYMGNGARYTNCARGARATGAGYGAYGARGGNATGTGYYTNAGYATG CAYCARCCNTGGGCNTCNYTNYTNGTNTGYGGNATHAARATGCAYGARGGNMGNACNTGG TAYTCNGCNCAYMGNGGNMGNYTNTGGATHGCNGCNACNGCNAARACNCCNGAYATGGAR GARATHCARGAYYTNGARCARTTYTAYAARCAYCAYTAYGGNGGNACNCAYYTNAAYTTY CCNAARGARTAYCCNAGYGGNTGYYTNYTNGGNTGYGTNAAYGTNGAYGAYTGYYTNGAR CARGGNCARTAYMGNGARAARTTYCCNAAYGGNGARTCNAGYTCNCCNTAYGTNTTYGTN TGYTCNAAYCCNTCNAARYTNYTNYTNAARTTYCCNATGAARGGNAARCAYAARATHTAY AARYTNGARGGNCAYATHCAYCARGCNGCNAARAARGGNYTNMGN--------------- ------------------------------------------------------------ ------------------------------------GARGTNATHYTNMGNGTNTGGAAR ATHATHCCNCCNTCNMGNGCNGAYTCNAAYCARCCNCCNACNCARYTNAARTGYTTYTAY TCNGARTTYAAYGARGARTCNAARATGMGNTCNGARATHCARMGNATGATGGGNAAYAAY GARATHATHTTYYTNGAYMGNYTNATHGARAAYCAYATHGAYTAYATHATHMGNYTNCCN MGNAARATHYTNYTNMGNATHYTNTTYAARYTNGAYYTNGTNTCNATHTCNCARYTNAGY TCNACNTGYAARTTYTTYAARGARYTNTGYATGAGYGAYGARYTNTGGTCNAARATHTAY ATGGAYACNACNAARAARCCNATHACNCARGARYTNYTNATGGTNGTNGAYACNAARGGN TGGMGNGARGTNTTYTTYATGAAYAARYTNCARYTNCARATGCARATGMGNMGNCAR--- GGNGARCCNTCNAARGARTCNMGNTTYTTYTAYGGNAAYAARTTYCCNTTYAAYTGYTCN TGYGTNGARGTNGGNATHYTNYTNACNGTNTCNGTNATHTTYATGGGNGTNCCNGTNGAR GGNTTYGAYATHGGNAARTGYACNAGYGARTAYCARATHGCNMGNCARGAYYTNAAYATH AGYGAYGAYGAYAGYCARGAYYTNACNTCNATHTGYACNGCNYTNMGNACNTAYMGNCAY TGYATHCARTCNGGNGCNGGNTGYAAYGGNGAYYTNGARTAYCAYAGYATHMGNAARATH GCNAGYMGNGARATGAARAARAAYAARTGYAAYGARACNGGNGTNATGGTNCARCCNTCN AARAAYAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TCNTCNTTYGGNACNAGYGARGAY TCNAAYGCNGCNCCNYTNGAYTCNGTNTTYGGNYTNATGAGYYTNTCNYTNATHTGGAAR TCNTAYYTNACNTCNTTYGTNTTYACNTTYGCNGCNTCNTTYACNTTYGCNYTNGCNAAR ATHTTYCAYACNGARCARYTNGARYTNCCNGTNACNAGYYTNATGGARCARTCNAGYGAY AARACNYTNCCNGAYGCNYTNGCNTGYACNTAYTCNCCNYTNYTNMGNCAYYTNGCNTTY TAYGAYYTNGCNTGYYTNAGYAARTAYGTNTCNCARMGNATHCARGAYYTNYTNAGYYTN AGYCARCCNGGNGGNCAYCCNAARGTNTGGATGATGGTNAGYGGNTCNGCNYTNTCNGCN ATHCARGARYTNGCNAAYCARGTNAARGARGARAAYTGGTCNATHATGTCNAARGTNCCN ATH---------AAYCARCAYAARAAYGGNGCNGCNAAYAGYAGYAAYTTYTAYTCNTCN GGNGAYYTNGAYTCNTCNYTNATHAAYMGNGGNGARGTNYTNTCNGAYGGNACNCARGCN GARTCNGARMGNCCNAGYGTNATGACNCARYTNTTYGGNAARYTNTCNTCNYTNCCNATH YTNTCNCARYTNYTNGTNCARAGYCARGAYTCNAGYAGYMGNMGNYTNTTYGCNTCNTGY CARATHCAYATHTGGGCNGTNGARAGYYTNTCNCAYATHGCNGCNMGNGCNTAYACNGAR GAYMGNTAYGGNGTNGTNCARAGYTCNYTNCCNATHATHTTYATGTCNYTNTTYGARYTN TAYGARGCNATGGARAARCAYTTYAARYTNAGYACNACNGCNMGNMGNAAYAAYGGNTCN ATHCAYTCNTCNACNGAYGGNYTNAAYMGNTAYAARYTNCAYTCNGTNYTNAARGCNTCN YTNTAYMGNATGGTNAAYACNTAYAARGAYCAYYTNGARGAYYTNAARYTNAARCCNGAY GARATHMGNMGNYTNGGNTCNTTYYTNCARTAYACNYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNATHGCNAAYCAYATHGGN GTNGCNAARTAYGAYAGYAGYTAYCCNTAYGAYCCNMGNTTYATHYTNGGNGTNYTNYTN TAYGTNATHGGNTTYGTNATHAAYMGNTGGGCNGAYTGGAARYTNMGNTCNYTNMGNCAY AARAARGGN------------------AGYAARGGNTAYTAYATHCCNTAYGGNGGNYTN TTYAAYYTNGTNTCNTGYCCNAAYTAYTTYGGNGARYTNGTNCARTGGATHGGN------ ------------------------------------------------------------ ------------------------TGG------------------------ACNATHGCN ACNTGGTCNYTNTCNGGNTTYGTNTGG--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AAYATHTGYACNYTNTGYGCNTCNYTNGAYGARCAYMGN AARCAYYTNCARMGNATGMGNATHCCNAARAARTGYATHATHCARAARCARACNATHCAR TAYGTNGCNCCNMGNCCNMGNGTNAARCCNGARCCNAARGARCCNGAYGAYCAYTTYACN GARMGNTAYAARGTNATHGTNTGGACNGGNAAYCARCCNGARGCNTCNTCNGAYGCNAAY GTNTAYYTNAGYYTNAARGGNGAYGARGAYATHYTNYTNCCNACNYTNYTNTGYMGNGGN CARTCNAARAARMGNATHTTYTTYGCNCCNGGNTCNAARGARACNTTYTTYGTNAARGGN CCNCARYTNGGNAAYYTNYTNYTNYTNTCNYTNGARCAYGAYGGNATGGARAARAARCAY GGNTGGTAYTGYGAYAARGTNGARATHACNTGYATGMGNTCNYTNCARCAYTGGATHTTY ATHTGYAARAAYTGGYTNTCNYTNCAYCAYGGNGAYTTYAGYYTNACNMGNACNYTNGAR GCNAARTAYYTNGARAARAAYAARATGTTYCARAARGGNAGYATHGAYAARTTYMGNTTY GTNATHAARGAYATHGGNAAYATHCARTCNYTNMGNGTNGARCAYGAYGGNAARGGNGTN GCNTCNGGNTGGTTYYTNGAYMGNATHATHYTNCARAAYGTNAAYCAYCCNAAYATHATH TAYTAYTTYYTNYTNAAYGGNTGGYTNGCNMGNGAYGTNGGNGAYGGNCARYTNGTNMGN GAYATHGTNGCNAARAARAARYTNGCNAARGARATHACNACNGGNAARCCNGTNGAYTAY TCNGTNACNGTNAARACNGGNGAYGTNMGNTAYGCNGGNACNGAYGCNAAYGTNTTYATH ATHATHCARGGNAARAARGGNACNACNAARAARYTNTGYATGGAYGAYTCNMGNGAYAAY TTYGARMGNGGNAARACNGARGTNTTYGARYTNAAYACNGTNGAYGTNGGNCCNATHCAR CARATHCAYATHGGNCAYGAYAAYTCNGGNCCNGGNGCNGGNTGGTAYTGYGARCAYATH ACNATHAARAARTAYYTNCAYCAYGAYGAYATHGTNACNTTYYTNAARAAYYTNAARAAR AARMGNAARCCNAARGAYCARAARMGNAARMGNYTNTCNGAYAARYTNMGNCARACNTCN YTNTCNGAYAARGARGARGARGGNTCNGARGARGARGARTCNGAYAARGARGARGAYGAY GARGAYAARGARTAYAARGAYGTNTTYGAYGTNGAYGGNAARGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGCCNACNTTYMGNATHGAYACNAAYYTNCCNMGNGAYAARATHCCN CARAAYTTYYTNAARGARGCNACNACNYTNATGGCNGGNYTNYTNGGNAARCCNGARTCN TAYATGTGYATHGTNGTNAAYCCNGAYTGYATHYTNAGYTTY---GGNGGNAAYCARCCN GCNGCNAAYGTNACNGTNCAYTGYATHGGNGTNGTNGGNCCNGARAARAAYAARCARATG GGNCCNGTNATHGCNAARTTYATHGARGARAARYTNGGNATHMGNCCNGAYMGNTAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GARTTYGGNATHTAYAARGTNAAYCCN CARATHMGNGTNYTNTAYAARACNYTNTCNGARATHGARGARAGYGGNGTNYTNGAYGAY TCNGGNAARYTNACNATHAAYGGNGAYGARGTNGCNGTNTGYTAYYTNMGNGAYGGNTAY ACNGCNGARAAYTAYCCNTCNMGNAARGARTGGAAYGCNMGNYTNAARYTNGARYTNTCN MGNGCNATHAARTGYCCNAGYGTNCARTAYCARYTNGTNGGNGCNAARAARATHCARCAR GARYTNGCNMGNCCNGGNACNYTNGARMGNTTYGTNAAYGARCCNGARGTNGTNGCNGCN YTNMGNAARACNTTYGCNGAYCARTAYAGYYTNGAYYTNGGNGARGARGGNGAYGCNGCN GTNAARYTNGCNYTNAGYTCNCCNCAYAARTTYGTNYTNAARCCNCARMGNGARGGNGGN GGNCAYAAYATGTAYGAYGAYGAYATHACNAARTTYYTNACNGARCAYGCNTCNAGYCAR GARMGNAAYGCNTAYATHYTNATGGARMGNATHTTYCCNYTNGARCARAGYAAYTAYYTN TTYAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GTNGTNGTNAARTCNACNGTNYTNTTYTCN TTYATHATGGTNTTYGCNTTYGGNYTNCCNATHGCNATGATHGTNATGGGNGCNATHCAY YTNGAYGARTGYCARGCNGARMGNATGATHCCNATHTAYYTNATHGTNGCNGGNTCNTTY GGNGTNTTYMGNAGYATHYTNACNATHTGYAAYMGNMGNMGNGAR--------------- GAYGARGARMGNACNATGGTNGAYCAYTTYGTNAGYGTNATHGAYTGYTTYYTNTTYGCN TGGTTYATHACNGGNTGYGTNTAYATHTAYMGNACN---AARGAYGARTTYCARTCNATG AAYAARACNYTNTCNAAYTAYTGYGAYCAYTCNTTYTAYTGGTTYGCNTTYTGGGTNGTN ACNGCNCAYTAYATHATHATHGGNATHATHYTNTTYATHYTNYTNATHGTNATGTGYTGY GCNGTNTGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATHATHAAYGARACNGAY GARGGNCCNAARGAYGCNATHMGNGCNTTYMGNAARMGNATHTCNCARAAYGTNGGNAAR AAYTAYACNGCNGTNATGTAYTGYYTNACNTGYATHGARTCNTGYGTNAARAAYTGYGGN MGNMGNTTYCAYYTNCARGTNGCNAAYAARGAYTTYYTNCAYGAYYTNGTNAARATHATH GGNCCNAARAAYGAYCCNCCNCARATHATHCARGARAARGTNYTNAGYATGATHCARACN TGGGCNGAYGCNTTYMGNGGNAAYCCNGARYTNAARGARATGGAYAARGTNTAYCARGAR YTNAARCARAARGGNATHGARTTYCCNATGACNGAYYTNGAYAAYATGGCNCCNATHCAY ACNCCNGCNMGNAGYGTNCCNGARAARGARCARCARTCNGCNAGYCAYGAYMGNGGNGGN AGYAGYMGN---GGNCAYGCNCCNGCNCCNTTYACNCAR------CAYCARCCNGTNCCN TAYCCNATGAAYCCNCCNGCNCCNATGGGNGAYGGNTCNGGNGGNYTNACNTCNGARCAR YTNTCNAARYTNMGNMGNGARYTNGARGTNGTNCARGGNAAYGTNMGNGTNATGGGNGAR ATGYTNACNGARYTNAGYCCNACNGAYATHGAYTCNTCNGAYYTNGARYTNYTNCARGAR YTNAAYMGNACNTGYMGNCARATGCARTCNMGNATHGTNGARYTNYTNAAYGARCCNGCN ACNGARGARGTNACNGAYGAYYTNYTNMGNGTNAAYGAYGAYYTNAAYAAYGTNTTYGTN MGNTAYGARMGNTTYGARMGNTAYMGNACNGGNCARTCNGGNCARGGNACNACNCCNATH TCNGAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARATHCCNCCNATHGCNYTNYTNCCNAAYTTYYTNGTNCAR MGNAARGTNYTNMGNCCNTTYMGNTTYCARGTNTCNGGNACNATHATGGCNGGNAARYTN GCNATGGAYMGNGGNTGGGCNATHAAYATHGGNGGNGGNTTYCAYCAYTGYTCNGCNGAY AARGGNGGNGGNTTYTGYGCNTAYGCNGAYATHACNYTNTCNATHAARTTYYTNYTNGAY MGNGTNCCNAGYGTNAARAARGTNYTNATHGTNGAYYTNGAYGCNCAYCARGGNAAYGGN CAYGCNMGNGAYTTYATGGGNGAYGARMGNGTNTTYATHYTNGAYATHTAYAAYMGNGAY ATHTAYCCNCAYGAYGGNTTYGCNAARMGNGGNATHAARMGNAARATHGARATHMGNTCN TTYACNGAYACNGAYGARTAYYTNCARYTNGTNMGNMGNCAYGTNGARGGNGCNYTNAAY GARTTYCARCCNAAYATHGTNGTNTAYAAYGCNGGNACNGAYATHYTNGAYGGNGAYCCN YTNGGNAAYYTNTCNGTNTCNGCNCARGGNATHATHGARMGNGAYCARATHATHTTYCAR AARTGYMGNACNMGNGGNATHCCNGTNTTYATGGTNACNAGYGGNGGNTAYYTNMGNGAR ACNGCNMGNATHGTNGCNGAYTCNATHYTNAAYYTNMGNAAYYTNMGNYTNATHTCNTGY GAYGARGCNGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNYTNATGTAYGGNTGYGCNAARYTNGGN ATGGAYYTNGGNATHGCNACNCCNACNGGNMGNGARCCNAAYACNGAYGTNATGYTNGAY GCNATHAARATHGCNGGNAARACNTCNTCNTCNATHCARTTYAGYAAYCARCCNGTNGAR GCNGTNTAYMGNGCNGAYGCNATHATHACNGAYCCNTGGCAYAGYAAYGARCAYGGNYTN AARAAY---AAYCARCARCCNGCNGAYTTYCARGGNTTYGARYTNAAYMGNAARATGYTN AARGARGCNGGNGCNAAYTGGGTNGCNYTNCAYMGNYTNCCNMGNCARCAYGGNGARACN TCNGAYGAYATHTTYTAYGGNAARGARTCNYTNGTNTGGCARGCNGCNGARAAYMGNATG TGGGTNAGYATGGCNGTNYTNYTNAAYGTNATHATHCCNTAYCARCCNACNATHACNMGN CCNAARTTYGTNAARGGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGTCNGARGAYAARTTYAARAAYAARGARGAYGAYCARGGNTAYAGY AAYCCNTGYGAYGAYYTNAARTCNGAYCCNGCNATHAAYYTNGTNTTYCARMGNATGTCN AARGARATGGARGARCAYAARGARAARYTNAARCARAARCARAAYGARYTNAAY------ ------------------------------------------------GCNTGGAARTTY ACNCCNGAYAGYCAYACNGGNATGMGNYTNATGGGNAARTGYMGNATGYTNYTNCARGAR AAYGGNGARYTNGGNAARATGATHTCNTCNGGNMGNACNGCNMGNYTNGARGGNGARATH TCNYTNCAYAARGCNYTNGTNGCNGARATGAARAARAAYCARAARGARYTNGAYGARTTY GTNGGNGARYTNGARGARGAYGTNGARGGNATGCARGGNYTNATHYTNATGYTNCARCAR CARYTNAARGARGCNMGNGARCARATHACNMGNYTNCARCAYGARAAYGARCARYTNMGN ACNYTNCARTCNCCNAGYGARTCNGAY--------------------------------- ------------------------------------------------------------ ------------------GARMGNGGNGARGAYAARACNGARAGYATGGARYTNCAYMGN GGNCARGTNCCNGARAARAAYAARGTNYTNYTNAARATGCARCCNCARMGNGGNGAYGAY ACNCCNMGNTCNATGGCNYTNAARGGNAARYTNACNAARTCNGCNAARAARMGNGGNATG TCNAAYTAYTAYATGATGGAYGAYGARGARMGNGGNYTNGARAARGARTAYTTYAARCCN YTNGARACNGAYCARGARGTNTAYGTNAARTCNCARYTNACNGAYGAYGARGARGAYTTY GARAGYCCNGCNAGYAGYMGNCCNACNTCNGCNTCN---------------TCNTCNGAY GARGARACNGGNACNTGGATHCARTGYTCNATHCAYCAYTGYGGNAARTGGMGNTAYGTN GCNACNATHGGNGAYCCNATHCARGTNCCNGAYTAYTGGGAYTGYTCNATGAAYACNGAY AARGARCAYAGYAGYTGYMGNGCNACNGARGTNGAYTAYGAYGARAGYGARCAYATHATG ACNAARTTYACNYTNGGNTCNGTNGTNTGGGCNAARATGGAYGGNTTYCCN--------- ------------------------------------------------------------ ------NNNAGYATGTAYCAYGTNACNTTYTTYGAYGAYCARGTNTCNMGNGCNTGGATH MGNTGYCAYYTNATHACNCCNTAYGARCAYAAYTCNGAYCCNAARAAYACNGTNCCNGTN AARTCNMGNTCN---AARAARGARYTNCARAARGCNATHAAYAAYGCNGARACNTCNYTN AARYTNAAYYTNGARGAYMGNYTNAARAARTAYAGYTTYGARAARMGNTTYAARMGNGTN GARAAYGGNGGNGAYGGNGAYCAYGGNGAYCARYTNAAYGGNGCNGGNCCNMGNTCNTAY ACNCCNGAYGCNTCNGAYYTNGARGARTTYGTNYTNMGNCCNGCNCCNCARGGNGTNACN ATGAARTGYMGNATHACNMGNGAYAARMGNGGNGTNGAYMGNAAYATHTAYCCNACNTAY TTYYTNCAYYTNGARYTNGAYAAYGGNMGNAARGTNTTYYTNYTNGCNGGNMGNAARMGN AARAARAGYGCNACNTCNAAYTAYYTNATHTCNACNGAYCCNACNGAYYTNACNMGNCAY GGNGARTCNTAYTGYGGNAARYTNMGNTCNAAYYTNYTNGGNACNCARTTYACNYTNTAY GAYCAYGGNGAYAAYCCNAARAARAGYGGNCARCARACNGCNMGNCARGARYTNGTNGCN ATGGCNTAYGARACNAAYGTNYTNGGNTTYAARGGNCCNMGNAARATGACNATHATHATH CCNGGNATGACNAGYGARCAYCARMGNGTNAAYATHAARCCNCARGGNGGNCAYGAYGGN YTNATHGARMGNTGGAARMGNAARAAYATGGARAAYYTNYTNGARYTNCAYAAYAARACN CCNGTNTGGAAYGAYGAYACNCARTCNTAYGTNYTNAAYTTYCAYGGNMGNGTNACNCAR GCNTCNGTNAARAAYTTYCARATHGTNCAYGAYAAYGAYGTNGAYTAYATHGTNATGCAR TTYGGNMGNGTNGCNGARGAYGTNTTYACNATGGAYTAYAAYTAYCCNATGTGYGCNYTN CARGCNTTYGGNATHGCNYTNAGYAGYTTYGAYGGNAARATHGCNTGYGARYTNACNGCN ACNYTNMGNACNYTNAAYAARTGYGAYTTYYTNAARGAYYTNGTNYTNATHMGNAGYYTN ATHTTYGARATHYTNACNYTNTCNACNAAYGGNACNGAYGTNAARCCNGCNYTNCCNATG ATHYTNAARYTNYTNGCNCAYCCNGAYACNTTYGTNAARMGNGTNAGYGGNGARATHATH TCNATHTAYGCNGARGAYAAYCARGAYATHACNYTNYTNGGNGTNAAYACNYTNGTNCAR GAYTGYAARGAYGTNAAYCCNGTNGTNMGNGGNATHAGYTTYMGNACNYTNGGNTCNYTN AARACNAAYTCNGTNTCNGARGCNYTNGAYAARGCNGTNGTNTCNGGNYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TCNTCNTCNTCNTGGGARGTNGTNGGNAARAARAARAARGGNGARTCNCARAAYCAR ---------CARAAYAARGARAARGARYTNYTNGAYAAYATGCCNAARGTNGARMGNTCN GAYCCNGTNCCNYTNGAYGARACNGTNTTYTCNGCNTTYYTNGCNAARGARAARCARAAR ------TCNGCNTCNAGYGCNAARGAYGAYGTNMGNCARAAYGGNAAYAARAARAAYTCN AAYCARAARAARAARAARCCNGAR---GARCAYAARAARAARCCNAARATHGTNGAYYTN AAYGTNGCNYTNTCNTCNYTNGAYGCNAARGAYATGGARGGNGTNYTNAGYCARTCNGAR GCNTAYTTYCCNAAYCAYCCNACNGTNTGGYTNAARGAYYTNGCNTCNTAYYTNAAYTTY AARTTYGARAAYACNGTNGAYAAYGAYCCNATHTAYAARGGNAARTCNGTNAAYTAYCCN YTNGAYGCNGTNCCNAAYGCNTGYTCNAARYTNYTNCAYAAYTTYATGAARAARTTYTCN AARCARACNYTNGAYAAYATHTTYTAYTAYGGNATHCARACNATGYTNCARGARTCNTCN AARGGNATHCCNGTNCAYGGNTTYAARATHTTYYTNCARYTNYTNTCNCAYACNAARCCN GAYACNGTNGTNGAYAAYYTNCCNCARTAYATGGARYTNYTNAARATGCAYCARAAYAAY CCNTCNAARTGYYTNTCNGTNYTNTGGGTNYTNGGNCARTGYGGNTTYAARAAYTTYAAY TGYGGNYTNAARGTNTGGYTNGAYYTNATGYTNCCNGCNYTNGARGTNMGNCARGTNGCN CAYTAYCCNGTNGARTAYYTNGARACNYTNATHMGNTCNAAYAARAARTCNACNAARAAR ------------AGYTTYGGNYTNGTNACNYTNMGNGARTAYTTYCARGTNYTNGAYGTN TTYTTYAGYCCNAARTTYACNYTNGCNCAYGAYYTNAARAAYMGNYTNAGYYTNYTNTAY CCNTTYATHAARACNYTNGCNTAYGGNGARACNCCNTCNCAYAAYYTNMGNACNTTYTTY CCNTCNTAYYTNACNMGNTTYAGYAGYACNCAYTCNAARGCNATGMGNGTNGARYTNYTN GARTGYYTNACNCAYTGYYTNATHACNGAYAARCARTCNTTYAGYGTNTGGTGYCARYTN TAYACNAARAAYYTNTCNGCNTCNAGYCAYYTNYTNGAYCAYATHAAYAARGARTGGCCN MGNYTNTCNTCNAARTTYGAYAARAARATHYTNACNGARACNYTNMGNTCNTTYTCNGTN ACNAAYGAYGARYTNGARYTNCARAGYAARGGNAARYTNGAYGGNYTNAARYTNTCNCAR AGYGCNACNAARGAYYTNATGYTNAARYTNAGYGGNACNCAYTTYCCNTGGAGYYTNYTN GTNTTYATHATGGTNACNATHTTYGCNTCNATHGTNGTNTAYGAYGTNATHTCNAGYCAR TCNTTYMGNTCNTCNAARACNATGCARTTYYTNGARCAYTAYGGNATHYTNGCNYTNYTN GAYAARACNTAYCARGCNATHAAYAAYGGNATHGCNYTNTCNGTNAARTGGYTNAARACN AAYTTYCCNATHTTYTAYGCNTCNYTNMGNGAYACNGTNGTNCCNTTYGTNATHTCNGTN TGGAARAGYTCNAARGAYTTYGTNYTNAAYGCNGARGTNGARTCNMGNCCNTAYMGNCAR YTNYTNTGGGARAARAGYATHCARYTNTAYCAYTGGGTNTAYGAYYTNTCNCCNGARTTY TGGYTNMGNTGYGARGARYTNGTNTGGYTNTCNTGGGARYTNYTNAARGAYTAYTCNTAY MGNATHTGGATHYTNGGNTCNGARYTNGCNGGNGARGCNGAYCAYTGGYTNACNGARCAY GTNYTNACNGGNTCNYTNTCNAARGAR--------------------------------- ------------------------------------AAYGAYTTYTTYCARGCNTTYYTN CAYTCNYTNMGNGCNTCNTGYTTYCARTTYYTNGAYTTYMGNAAYCAYGTNAAYGTNMGN GGNTTYGTNTCNGTNGARGTNGAYGGNGTNAGYCARCAYCAYYTNGTNYTNGCNGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GAYATGAGYTCNAARAARGTNYTNGAYCCN AARMGNTGGAAYTGYATHAGYMGNCCNCARTAYAARMGNTCNTGYGGNATHTCNAGYYTN GTNTCNTGYTGGAAYTTYYTNTTYTCNACNATGGGNTAYGGNCAYYTNCAYCCNYTNACN CARGARGARGCNATGACNATHYTNGGNTTYGAYGCNCCNTTYGAYGARATHGTNTTYGGN CCNTTYACNGGNAAYYTNACNYTNATHMGNTGGTTYCAYYTNYTNAAYGARCAYTTYAAR GTNCAYGGNMGNGCNTAYTAYYTNTAYAARCCNAARGGNAARAARMGNACNGTNGGNGTN ACNGCNGARATGGCNYTNGAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNAARMGNMGNTTYAGYGAYGTN------GCNGAYCAYTAYAARGGNCCNCARGAR TTYATHGARGCNGGNGTNMGNGGNTTYYTNGTNACNTGYCARCCNGAYMGNGARGARCAY GCNATHGAYGARTCNATHAARATHYTNMGNAARACNTGYGTNAARYTNTAYGGNGGNATH AARCCNYTNAARCCNGARGAYGCNGCN------AARGGNTAYGTNATGATHGAYTTYATG AAYCCNGAYGAYGTNGARYTNYTNCCNCAYCCNGAYGCNGARAARCCNGTNGARGCNGAR ---------------------------------------------------ACNGARAAR CCNACNGARGCNCCNGCNGARAAYGTNGARGCNGARGCNGARGCNAARGGNGAYGCNCCN GARGARGARGARAARAARGAR--------------------------------------- ---------------------GARGTNAARGARGAYGTNAARGARGARACNGAYAARAAY CARCARGARGAYAARGARAARGARAARGARAARGAR---------TCNCCNAARAARCCN AARCAYGARGARMGN--------------------------------------------- ---------MGNMGNMGNCCNYTNATGYTNGCNAAYMGNAARTTYAARGGNTTYMGNACN GARYTNMGNAAYATGATGTTYGTNAARTCNGAYATHGCNGAYCCNGTNGARGTNYTNGAY AAYGCNTTYGARYTNATGGCNGAYMGNAARCCNYTNATHACNGAYGTNATHAAYCARYTN YTNCCNGTNCARGGNGTNTGYGARAAYGAYTAYAARCARYTNGARATHATGTGYMGNMGN GTNYTNGARCCNTAYYTNTCNGARCAYATHGARGARCCNCCNAGYTTYGGNGTNYTNTTY GTNGAYAARATGTGYGARCCNGGNGGNGARGTNYTNYTNGARGTNGTNMGNAGYGCNATH TGGAGYYTNAAYCCNGCNGCNTGGCARTGYTCNCCNTGGTGYGARCCNGAYGTNGTNGTN MGNGTNGARATHATHGGNAGYAARATHGTNYTNAGYGCNATGCCNCAYTAYATGAARTAY MGNCARTAYAGYCCNYTNGCNGTNTAYGARATGGGNTTYGGNAARCCNAARGAYGARGAY GARYTNGTNAAYGARGCNAARMGNCAYGARGARGARGARGARATHMGNAARACNAARAAR AARAGYGGNACNAAYAAYAARGGNAARGARAARGARAARGGNGARGARAARCCNGCNGAY GARAAYAAYAARGARAGYGARGCNCCNGCNACNGARCARAAYGCNGARGARGARCARAAY GGNAARACNGARGARGCNGARAARGTNGARGARGAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ACNTAYAARGCNCAYGARAAYAGYMGNTTY ATGAARAARYTNATHAAYAARAARGGNGCNAARAAYAARAARCARTGGTAYAARCCNCAY YTNGGNGARTCNYTNGARYTNGGNCARMGNAARACNAARAARGARGTNTCNCARACNCAY AGYATHMGNYTNMGNCARTGGAGYCAYGTNYTNTAYGAYAARATHACNGARATHATHAAY ACNGGNGARYTNTCNCARGARGTNYTNGAYGCNCARGTNGCNATHACNTCNGCNTCNATG GCNAARGAYATGAAYAAYGTNAAYGTNTAYTGGGAYGCNGAYMGNAGYGAYTGGGARGCN GTNGARYTNGTNYTNCARTCNAAYTCNGGNAARYTNMGNAGYYTNYTNATHTCNTAYCAY GTNYTNGGNMGNATHCCNCAYATHGTNTTYGTNAARAAYAARGGN---AGYGCNGAYYTN AGYCARYTNAAYCARYTNTTYGAYCARGCNGAYTAYGGNCCNGAYTAYGTNCCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CCNYTNCCNCCNGGNTGGGARGCNMGNTGG GTNCCNGARCARAAYMGNTAYTTYTAYATHAAYCAYCARCARAARACNACNCARTGGGAR GAYCCNMGNTTYCAYATHMGNCCNACNCCNCARGCNGCNGCNGCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AAYMGNMGNMGNAARAAYAAR AAYAARAARAARMGNMGNMGNAARAARAARGGNAAYAARAAYATHTGYAARAARCAYGCN ATGTAYGTNCAYTTYACNGARGTNGGNTGGGAYGAYTGGATHYTNGCNCCNCCNGGNTAY AARGCN------------------------------------------------------ ------------------GCNATHGARATGCAYTGGGARCCNGTNGCNCCNYTNGGNCCN CARGCNGCNTAYCAYGTNGGNTGYATHATHMGNGGNAAYATHTAYYTNCAYGGNGGNATH AARGAYYTNAARTCNAAYCARCCNTCNTCNCARYTNTTYAARYTNAAYYTNCARACNAAY ATGTGGGARGTNATHTAYACNACNGGNAGYCCNACNYTNAGYCAYCAYGCNTGYGTNGTN AGYGARGAYMGNTAYATGATHATHGTNGGNGGNTGGAAYGGNAARMGNMGNAGYTCNGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TAYGCNMGNTCNATHYTNACNGTNCCNTGGGTNGARYTNGGNGAYAARGTNGCN YTNACNTGYGAYAARACNGGNTAYAGYGCNAGYATHGTNTTYAAYACNAARCCNTTYTAY GGNGGNAARYTNCAYAGYATHACNGCNGARGCNAARAAYACNAARACNGGNGARAAYATH TGYAARGTNCARGGNCARTGGAAYGGNATHATGGARTTYAGYTAYGCNAAYGGNGAYTCN CAYACNGTNGAYGTNTCNGARYTNCARGTNACNMGNAARTCNGTNMGNCCNATHGARAAR CARGARGARCAYGARTCNMGNMGNYTNTGGCARCAYGTNTCNCAYGCNYTNAARATGAAY GAYATHAAYACNGCNACNGARCAYAARMGNCARYTNGARGARGTNCARMGNGARMGNGAR MGNCARMGNAARGCNATGAAYATHCCNTAYGTNGGNAARTTYTTYGAYAAYGTNGAYGAY ACNTGGGTNCAYAARAGYTTYCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TTYGCNGTNGGNYTNTCNGTNGTNYTNATHGAYGTNCCNTTYGAYATHATG GGNGTNAARYTNYTNTGGTGGACNTGGCAYGAYGAYGAYCCNAAYATHTAYGAYMGNCAY TAYTGGGTNCCNTGGACNTCNTAYTAYTTYCAYGCNGCNTTYGCNTCNTCNTTYGCNTTY ATHTTYTTYAAYGCNAARAARYTNGTNTGYTCNAARACNYTNAARTTYCARAGYAGYGGN TTYTTYYTNGARTTYCCNGTNYTNATHYTNACNGGNYTNTTYTCNATGCCNYTNGGNGTN YTNCARTTYGTNCCNATHTAYCAYTCNATGCAYGAYACNYTNGGNATHCAYTCNGARGTN TGYGTNYTNYTNTAYYTNGCNGTNTTYGCNTTYATHGTNTGGACNGCNGAYMGNMGNCCN YTNGARYTNGCNMGNCAYAARGGNGGNGGNATGTTYAGYYTNATGYTNYTNTCNATHGTN ATHCAYTAYGCNTTYTAYGTNTAYYTNGTNTTYACNGCNAAYCCNGCNGCNATHMGNTCN AGYGGNYTNCAYCARCCNGTNGGNCCNTGYAAYAARCARGTNAARGTNCARACNCCNTTY GGNCAYGTNYTNAARAARACNCARTAYYTNTGYYTNAARAAYTAYTCNGARGAYTAYTTY ACNYTNGAYTGYYTNAARAARCCNCCNGCNGAYAARACNGARAAYTAYACNATHTGYGGN ACNCCNTAYCCNAAYCAYAARGARTAYATGGTNGTNGTNTGYGCNTTYTGYGCNATHGGN YTNTTYTGGTTYATHCARGCNTTYTGYMGNTCNGGNATGCARCCNMGN------------ ---MGNAAYGCNTTYACNATHTTYGCNAAYATHTCNGTNTAYGGNATHTTYACNYTNYTN TTYTAYATHGAYTCNGARCAYGAYTCNTCNGGNATHGAYGAYGCNCCNAARTTYMGNAAY YTNACNATHATHTGYYTNTCNYTNGGNGTNYTNTTYAAYYTNYTNTTYTAYACNACNATH GARTGYTCNACNATHGARAARTCNYTNATGATHTGGAARGAYTGGYTNAARGARYTNCAR TTYTAYCARATHGCNATHYTNTAYATGTGYACNMGNYTNTAYATHAAYGTNAGYCARGTN TAYTTYTCNATGTAYYTNACNGARACNATHGGNYTNAAYAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTNAGYATHATHYTNTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GAYAARMGNAGYAAR TCNMGNTCNAARTCNMGNTCNMGNTCNGCNTCNCCNMGNAAR---AARMGNAGYMGNAGY MGNAGYMGNCAYTCNMGNTCNMGNTCNMGNGAYMGNMGNCAYAARMGNGARMGNAARCAY MGNTCNCAYMGNTCNAARTCNAARGARMGNMGNMGNTCNMGNGAYMGNCAYMGNCAYAAR AARGAYMGNAARMGNAGYMGNAGYMGNAGYMGNAGYMGNGAYMGNAARGAYMGNAARTAY GAYMGNAARAAYMGNAGYMGNGARMGNAARMGNMGNAGYMGNAGYMGNAARMGNAGYMGN AGYMGNGAYMGN---MGNAGYMGNAGYMGNMGNMGNAGYACNMGNAGYTCNAGYCCNCAY CCNGGNAAR------GTNATHAARTTYGGNGAYAARGTNATHAARCCNGGNGCNAGYTTY GGNMGNCCNACN---AGYTCN------TCNAARCCNGTNACNTTYAARGARAARATGMGN CARGARYTNATHAARGCNATHGARGAYGGNGCNGAYACNAAYGAYGTNYTNGCNAAYAAR GGNGGNTCNAARATHTGYACNCARTCNGCNGGN---GTNCARCAR------YTNGCNTCN AARCCNAARACNCCNGTNCCNYTNATGGAYAARATHATHACNTCNACNGGNAGYYTNCCN CCNATGACNGTNACNGCNTCNGARGCNGTNATGCARTCNATGYTNGCNYTNCARAARGAR ACNACNGARAARACNGGNATHGARATHCCNAARTAYTAYAAYCCNGCNGCNATHAAYCCN ATGAARTAYGCNGARCARGTNCARAARMGNAARYTNYTNTGGTCNAARGCNAARGARAAR GAYGTNAAYTCNCARTGGCAYGCNACNAGYYTNTCNGGNGAYGCNGAYGAYAARTCNAAR GARAARTTYMGNAARYTNATGGGNATHAARGCNTCNGGNGGN------AGYGGNTCNCAR ------------GARGGNGARCARGAYGARAARCARAARCARYTNTTYGAYCARYTNAAY AARGARTAYGARTTYGCNMGNATGACNACNCAYACNAAYMGNGGNGTNGGNYTNGGNTTY GGNTCNATHGGNTTYCARCARCCNCCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CAYCCN GARTTYYTNGCNAARTTYCCNGARGGNAARGTNCCNTCNTAYATGCARGTNCCNGCNGTN CARACNAAYAARAARGAYATHYTNTGGAAYAARAARMGN------GCNAAYCARGGNGGN YTNAAYTCNGTNGCNGARTCNGARATHACNAARGCNATGGCNGGNTTYTCNATHCCNTCN GARAAYGTNCCNACNTGGGCNAARCARATGACNGAYGAYCARTGGCAYAAYGTNATHGTN AAYCARYTN--------------------------------------------------- ------------------------------------------------------------ ---------------------CCNATHAARGTNGCNTCNTTYAAYATHMGNCAYTTYGGN MGNAAYGTNGTNAAYAAYGARGARGTNYTNTCNGCNATHGTNAARATHATGGAYMGNTAY GAYGTNGTNYTNGTNYTNGARGCNMGNGAYGCNACNAAYACNGCNYTNCAYAARYTNAAY GAYATGYTNACNAARTCN---GGNTCNTGGAARTTYGARAARAGYAARATHYTNGGNMGN AAYAARTAYTAYCARGARCARTAYGCNTTYTTYTAYAARACNACNTCNGTNTAYYTNATH AAYACNTAYCARGTNAARGAYACN---AARGAYCAYTAYGARMGNGCNCCNTTYGCNGCN GARTTYATHAGYGARTCNTTYGARAAYAARCARATGACNMGNTTYGTNYTNTTYGGNTTY CAYTCNAARCCNACNGCNACNAARCARGARYTNYTNGARYTNCCNAARTCNATHACNTAY GTNAARAGYMGNTTYCCNMGNGCNGAYGGNYTNATHGCNYTNGGNGAYTTYAAYGCNGAY TGYAGYTAYYTNTCNGGNAARAAYMGNGAYTCNTAYAARATHTTYCAY---GGNTCNAAR TTYAARAGYYTNATHGGNGAYGAYGCNGAYACNGCNGTNGGNAARTCNACNGARTGYGCN TAYGAYMGNGCNGTNGTNTAYGGNGAYAARYTNGAYGTNMGNGAYGCNGGNGTNTTYGAY TTYGARAARGCNTAYGGNYTNACNGARAARGARGCNYTNAARATHAGYGAYCAYTTYCCN ATHGARTTYTCNYTNTAY---TTYAGYGTNAAYYTNTGYATHGGNCCNACNTAYGAYCAR GAYTGYGCNYTNCAYTTYAAYCCNMGNTTYGAYCARAAYGARGTNGTNMGNACNCAYCAY CARGGNGGNTCNTGGGGNAAYGARGARAARGCNGGNGGNTTYCCNTTYAARMGNGGNCAY GTNTTYGARATHCAYATGAARGCNAAYCAYCAYGGNTAYAARATHACNGTNAAYAAYMGN CAYTTYTGYGAYTTYCAYAAYMGNYTNCCNMGNGARAGYATHCARTAYATHTAYATHGAR GGNGARGTNGAYATHCAYTTYATHCARTTYMGNGGNGGNCAYGGNYTNCCNACNCCNGGN TAYCCNGCNGTNCCNGGNTAYCCNCCNGCNGCNCCNGCNTAYCCNCCNGCNCCNGTN--- ------GGNNNNGGNTAYCCNCCNGCNNNNGGNNNNNNNNNNGCNCCNGCNTAYCCNCCN GCNGGNGGNGCNCCNATHTTYAAYCCNCCNGTNCCNTTYACNGCNCCNATHCARGGNGGN GTNGTNCCNGGNAARATHATHTTYATHTCNGGNATHCCNAAYYTNAAYCCNAGYMGNTTY ACNGTNAAYYTNCARTGYGGNCCNTAYGAYTCNGGNGAYTTYGCNATGCAYTTYGAYGTN MGNTTYAAYTAYGGNAAYTCNTAYAAYCARATHGTNMGNACNCAYAARCARGGNGGNAAY TAYGGNAAYGARGARGGNGCNYTNACNCAYTTYCCNTTYAGYCCNAAYACNCCNTTYGAR ATGATGATHYTNATHGARCCNACNTCNTTYAARGTNGCNGTNAAYAAYCARCAYYTNGTN GARTTYTTYCAYMGNATHCAYCCNTTYAAYMGNGCNGAYCAYGTNAAYATHGTNGGNGAY GTNMGNYTNACNCARATHMGNTTYCAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ACNAAYAAYACNACNAAYYTNTCNGARAGYYTN TCNGARYTNGARAARAARMGNAARACNGGNGAYYTNAARYTNAARGARTGGYTNCARAAR ACNGGNAARYTNAARACNAARMGNGARGTNTCNGTNAARGAYGCNACNACNAAY---GTN AARATHAAYCARTTYATHACNAAYYTNCARYTNAGYTTYTCNATHYTNAAYAARATGACN ATHCARGTNGAYAARATGGGNTCNATGATHCARGAYGCNGAYMGNTCNATHTGGCARGAR GARTGYAAYACNATHCAYCARYTNAARGTNGARCAYGCNGAYYTNCARAAYATHGTNGAY AARGTNAARGTNMGNAARGTNCARAAYAARYTNCARMGNATHAARAGYAARAARGCNMGN YTN---------AARMGNATGGCNCARGAYMGNYTNCAR---CARAARGGNGARYTNGAR AGYAARGARAARGARATHGAYGARTGGCARGARAARATHAGYYTNGAYATGAARGARGAR AGYATGAARAARAARMGNAARGARGARATGGAYCARCAYYTNGGNGARATHAGYMGNAAR ATHAAYGAYGCNAAYMGNYTNATHGARACNATGACNGCNYTNGARAARYTNMGNYTNATH MGNCARGAYGCNGCNAARAARMGNGGNGAYGCNGAYYTNGGNGARTCNMGNGARAGYTTY GARCARAARATHGCNGAYATGACNMGNYTNGTNMGNTGYCARYTNGARGTNTAYAARGAR GARGARGARCARATHMGNAAYGCNATHCARTCNGARCARGAYGCNACNAGYGARAARGAR MGNCARYTNCARGARCARCARGARYTNGARGCNAARATGCARAARGAYGTNGARATGTAY AARAARYTNTTYGGNATGGARAAYGAYATHGAYGAYYTNYTNGAYGARGTNGARTCNAAR TTYGTNAAYMGNAAYMGNAARTCNGARTCNAARGCNGCNATHGARACNTCNAGYTCNMGN GTNAARCCNAARTCNAGYGTNGTNGAYGARGCNATHAAYGAYATHYTNGAYYTNGAYYTN GAYGAYAGYTAYGTNAARAARCARGGNTCNACNAGYAGYGTNACNTGYACNYTNACN--- ------AAYGGNGARAARMGNACNGGNACNAARAARTGYTTYCCNGTNTTYYTNGGNGGN AGYAAYGAYGARGCNGGNYTNGGNACNACNGTNAARACNMGNGCNTGYGAYCARYTNMGN TGYACNGCNTGYGAYTTYMGNGTNTGYTTYTTYGAYGARTAYTCNTGGAARAARGAYACN AAYTAYYTNTTYYTNMGNAAYAAYGTNCCNGAYTTYCAYAARYTNAARACNAAYYTNMGN MGNYTNAARGGNTGYMGNGCNTAYTGYTGYCARTGYAGYTGGMGNGAYGTNCARGCNYTN CARGARGTNTCNGAYCCNGAYYTNAARTGGGTNTGYGGNAARCAY--------------- ---------GCNYTNATHTGYTTYTTYTCNATHTGGTCNGTNGTNGGNYTNGCNGGNTTY CAYTCNTAYYTNACNGCNTCNGARATHACNACNAAYGARGAYATHAARGGNACNTTYACN TCNAARMGNGGNCARGAYAAYTTYAAYCCNTTYAGYMGNGGNTCNATHTTYAGYAAYTGY ATGAGYATHYTNTGYGGNCCNGTNCCNCCNAGYYTNYTNGAYMGNMGNAARYTNATHGTN CCNGARYTNGARTCNCCNGCNCCNAAYACNATHGTNGGNCCNMGNGCNGTNCARGCNMGN AAYGTNACNGTNGTNTCNGAYCARGGNGARGTN---------AARAARCAYAAYATGATH AGYTAYCARGGNCCNGAYGGNTCNATHTCNAAYAARYTNCCNGTNCAYAAYGGNTCN--- ---------GGNCAYMGNGTNAAYATHTAYCCNACNGCNCARGARGGNGTNAAYTTYTAY GGNGGNCCNGTNACNCCNCAYGGNCCNAARGAYGCNTAYATHCCNACNACNGGNTAYCAY AARGARAAYTAYAARTAYCAYATGCCNMGNGGNGTNTCN--------------------- ------------------------------------------------------------ ------------------------------------GARTGYCCNTAYAAYAARTCNCAY YTNGTNACNCCNYTNAARATGCCNTAYCAYYTNCAYAARTGYMGNAARAAYTAYCCNGAY YTNAARATGGCNGTNTGYCCNTAYAAYGCNAAYCAYGARATHMGNGCNCCNGARYTNAAR TAYCAYATGGCNCAYTGYCCNAAYMGNACNYTNYTNGARMGNGAYATGACNTAYAAYGCN ATHCARAAYGCNGTNYTNGGNAARGAYGARCCNGCNGTNAARGGNAAYACNGAYYTNCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARAARGARGARGGNTTYGAYATHGTN GARCARAGYGTNCARYTNACNYTNCAYAAYCAYCCNCARGTNGARACNTCNGCNYTNTTY ATHCARMGNGARGCNGCNATHTCNGAYTCNGGNGAYYTNAAYGCNGGNYTNGTNAGYATH TGYCARCARTGGATHGCNYTNAAYAARAAYGGNMGNATHATHATHATHTGYGAYGGNAGY AARGTNYTNAARAAYGAYAAYYTN---------GTNAAYAGYAARATHTGYCARGTNTTY AAYTCNYTNTCNGTNAARYTNTTYCARCCNYTNTAYGTNYTNAARTCNTCNMGNACNAAY TCNAAYACNTTYTGYGCNCCNCCNCAYCCNGGNATGYTNGCNTTYYTNCARTCNCARCAY GGNATHAAYYTNATGGCNAARCAYACNGTNTAYATHTTYGARACNACNGARCAYATGCAR ATGTCNYTNTCNGCNGGNATHAARTGYGTNAARAGYAARCARGCNTAYMGNTAYCCNGCN AARGTNTTYAGYAAYYTNGGNGTNACNCCNTCNGTNCCNGCNATGYTNAARGARATG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR CARAGYYTNMGNTGYGCNTCNGGNGCNAAYTCNCAYTAYGTNYTNYTNCCNGARGTNCCN CCNGAYACNGCNGARTCNAAYGCNGTNATGMGNGTNGAYCARYTNCCNCARTTYTCNCAY ATHTCNCCNTAYACNTGYYTNACNGGNTGYGCNAARYTNACNATHGARTAYGARACNAAR TTYGARAARCAYGTNGAYAGYYTNAARGAYCCNAARGTNGARAARAGYTTYGAYGAYGTN TAYYTNCCNATHGARGAYATHTCNGTNCCNYTNAAYACNGCNTAYGCNACNYTNAARAAY YTNMGNTAYGAR------AAYGAYGAYTAYMGNMGNGCNTTYTCNAARGTNCAYCCNCAR GTNGARMGNGTNAARAAYGAYMGNTGGATHAGYCARACNYTNTAYTAYGCNTTYAARGAR YTNGARGCNAAYAGYGCNAAYYTNACNGAYTAYCARAARMGNYTNGTNGAYYTNTAYYTN YTNGARGGNAARYTNAAYGGNGTNCAYYTNTCNACNGARGAYAAYATHAARYTNGTNGAY MGNYTNAARGTNATHGCNAARGARAGYGARAAYTTYMGNAAYAARGTNCARATHTGYACN AGYGTNTTYTCNCAYGAYGTNACNAAYTTYAAYGCNATHGARGARATGCCNTGGCCNYTN YTNGCNCARATGTCNAARGAYMGNTCNGAYCCNACNMGNGGNCCNTGGMGNGCNACNYTN CARCCNAGYGTNTAYCARGCNATGATGTCNTAYTGYAGYAAYMGNYTNACNMGNTGGAAY YTNTGGAAYGCNTTYCAYAAYMGNGCNTCNTAYAAYCAYGCNAGYCARTAYYTNAGYAAY GAYAARYTNATHGARAGYYTNMGNYTNTAYMGNCARGAYGTNGCNGARATGYTNGGNTAY GAYCAYTTYGCNGARATGTCNATGGARACNAARATGGCNGGNTCNGTNGARAAYGTNYTN GGNATGATHGARACNYTNMGNTCNMGNTTYGCNCCNGTNGCNTGGGARGARATHGCNCAR YTNCARCARTTYGCNTCNTCNGARGGNTTYAARCAYTCNYTNGARATGTGGGAYYTNAGY TAYTGGMGNMGNMGNCAYMGNGARCAYYTNTAYAGYGTNAAYACNGARGCNATHAARCAR TAYTTYCCNATHAAYTCNGTNYTNYTNGGNYTNTTYGAYYTNTGYACNAAYYTNTTYGGN ATHAAYTTYGARGARGTNACNCCNGARGTNGARACNTGGCAYTCNGAYGTNMGNTTYTTY AAYGTNYTNGAYGGN---GAYGGNAARCAYATHAGYTCNTTYTAYTTYGAYCCNTTYGAR MGNCCNGGNAARATHTCNCCNGGNTAYATGGGNYTNGGNMGNGAYAAYAGYGARCAYTGY GGNACNTGGCCNTAYTCNTAYYTNTGYYTNAARATHCCNMGNCCNGCNTCNTCNTCNGAY CCNATHYTNATGMGNTTYGARGAYATHGARATGYTNTTYGCNGARTTYGGNCAYGGNYTN CARCARATGYTNACNCARGTNCCNTAYAGYGARATHGCNGGNCARAARAAYATHGARTGG GAYTCNGTNCAYGTNTGYGCNAARTTYATGAARCARTGGYTNACNGTNCCNTCNYTNGTN AARGGNYTNAGYAAYCAYCAYCARTCNGGNGARCARATHCARGAYGAYATGYTNGAYAAY ATGYTNAARGCNAGYCARCAYATGAGYAAYTTYGAYATGATGCAYCAYYTNTAYGTNTCN GCNTTYGAYYTNGARATHTAYATGACNAARACNCAYTGGAGYTCNGTNATGAARCARYTN TGGGAYAAYTTYATGCCNYTNCCNYTNTGYGARGARGAYCARYTNCCNTGYTCNATGATH CCNATHTTYTGYGAYCCNTAYCCNGCNGCNTAYTAYTCNAAYAARTGGTCNGARATGATH GCNGTNGAYATHTTYTCNGCNTTYCARGARGTNGGNYTNGARGAYCARGARAARYTNAAR ACNYTNGGNAARMGNNNNMGNGAYACNTAYYTNTCNYTNGGNGGNGGNYTNAARTCNTGY GARGTNTTYMGNCARTTYMGNGGNMGNGAYCCNACNACNAARGCNYTNCARCCNATGGAR AAYAAYAAYGCNATHGCNGCNAARCCNGARYTNGAYGGNGARTCNAARATHGARGAYGTN AARCCNACNGCNGARGAYACNGAYTCNTCNCCNAAYAAYMGNMGNTAYAAYMGNMGNMGN MGNCCNCCNATGMGNMGNGAYGGNAAYCCNGARGAYGARACNGCNAARGCNGCNATHMGN MGNAARATHTGGGAYCAYTTYGARGAYGARAAYYTNGTNAAYGCNCCNMGNCCNTGYCAY TAYMGNATHCCNAAYTTYGARGGNGCNACNGARGCNGCNGAYAARYTNACNACNYTNGAY GARTTYAARAAYGCNMGNACNATHAARGTNAAYCCNGAYAARGCNCARGARCARATHMGN YTNYTNATHYTNGARGCNGGNAARGARYTNGTNYTNYTNAAYCARAAYGARAARGAYYTN ATGGTNCCNACNCCNGARYTNAARTGYGGNYTNYTNAAYMGNGTNGARGCNCCNGARGGN ACNAAYAARGARGARYTNAARCAYTGYTGYACNACNCARGGNGTNAARGARAAYTGYAAR GARATHGGNYTNGARGAYAARGTNAARYTNGAYATGATHGTNGTNGGNAGYGTNGCNGTN TCNMGNAAYGGNTAYMGNATHGGNAARGGNAARGGNTAYGCNGAYYTNGARTAYGCNATG ATGMGNACNYTNGGNGCNGCNAGYGCNAAYACNGTNGTNGTNACNACNGTNCAYGAYTCN CARGTNATHGAYATHGCNGAYGAYYTNGTNGGNGARCAYGAYATHACNGTNGAYTAYATH YTNACNCCNACNGARYTNATHAARACNAAYTGYAARMGNCCNMGNCCNTCNGGNGTNATH TGGAAYCAYYTNGARGTNAAYAARTTYTAYCARGTNCCNGTNYTNMGNCARYTNMGNAAR AAYGARAARGAYGAYGGNAARGAYGTNYTNYTNAARGAYCARAARGARGARGAYGARGAY CCNGTNGAYACNATGGARCCNCCNMGNCCNMGNMGNTAYGTNMGNAAYTAYMGNAGYGCN GGNGGNTAYMGNGGNMGNGGNMGNTCNTAYGGNMGN---TAYCCNMGNGGNGGNAGYMGN MGNMGNCARTAYGAY---GGNGAYGAYAGYAAYAARGARAAYCARGAYGCNGGNGARGAY TCNGGNGCNGAYGGNGAYAAYGARGGNMGNTTYAAYMGNMGNAAY--------------- AGYTAYMGNAAYMGNMGNTAYMGNMGNGGNGGNGGNGGNMGNCCN---MGNGCNTCNGAR TCNGARCAYAGYGARGGNGGNGCNGAYGARAAYMGNGARGAYGGNGAYGAYMGNACNMGN CARMGNMGNTAYAAY---AAYMGNMGNMGNTAY------------CARCCNMGNMGNMGN TTYGAY---------AAYMGNMGNGAYAAYMGN---MGNGARGAYCARTCNGGNAGYGAY GGNGARCAYAARAAYTCNGCNGAYGARGAYGGNGARGGNMGNMGNCCNMGNMGNAAYMGN ATHCARACNAAYCCNGAYGCNGTNGTNTGGGTNGGNTCNYTNTCNMGNACNYTNMGNGTN AGYGARYTNAARGTNGARYTNMGNAARCAYGARGTNAAYCCNATHMGNYTNYTNTGGMGN GGNGGNCAYGGNTTYGCNTTYYTNTTYTTYATGGARGTNGARGGNGCNAARGARGCNGTN AARATHYTNGCNGGNMGNGARYTNTGYGGNMGNGARATGAARGTNGARATGGCNAAYATG GAYMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARCARMGNATGGARCARMGNCCNCARGAYGTNAGYGAY GTNGARMGNCARTAYYTNGCNCARTGYACNAGYGARGARCARMGNCARAGYYTNYTNGCN TCNGGNGCNTTYGGNAAYGAYTCNGCNGCNATGGCNGCNYTNAGYGCNTTYTAYGGNCAR YTNGGNGTNGARATHGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNGTNGGNTAYGGNATH GGNMGNTTYTCNTCNTGYCCNATHGCNMGNTAYCARYTNGCNTAYYTNYTNYTNGTNCAR GARAARYTNCARACNATGCCNCCNYTNYTNTAYGAYCCNGTNTTYTCNTCNGARGARAAR ACNTTYYTNGARGAYYTNGGNTGYGARYTNATHCCNTAYAAYGARGARGGNAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR YTNAARCARAAYCAYCARGCNCARYTNAAYACNYTNACNMGNGARCARGARGCNCARATH CARAARYTNAARGAYGARGTNACNCARAARATHTCNTCNGARCARCARAARYTNACNTCN CARYTNGARTCNGARAARYTNAGYYTNCARMGNCARCARGARMGNGARYTNGARGARATG AARAARTCNTTYACNATHAARATGGARGCNYTNAARGAYCARYTNGAYGAYGARGAYGAR GARATGAARGARAARAARGCNGAYATHGARMGNMGNATGGCNTAYGTNGARAARTCNATG AARATHYTNGARTCNCARGARACNAARYTNGARGARMGNMGNAARAARTTYGCNGTNGAY AARGARMGNYTNGARCARGAYCARGAYGARGTNYTNGGNTCNMGNGTNTCNAGYYTNGGN GARGCNGARYTNACNMGNATGMGNGARGARMGNMGNCARYTNTCNCARGARYTNMGNGAY GARCARAAYAARYTNGAYAARACNAARCARGARMGNAARACNYTNGARGGNGAYGTNACN MGNYTNAARATGGCNMGNGARCARCARAAYAARAARYTNGTNGARATHMGNGARMGNGTN GARACNAARYTNAARGARTTYGARGGNYTNCARGAYAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GCNYTN CCNCCNYTNMGNCCNAARATHATHMGNGTNGARCARGTNGARGGNTCNGCNYTNTCNACN GCNTCNCAYMGNCCNTTYCARMGNGARAAYYTNACNTAYYTNAAYCCNYTNGGNGTNGGN TGGTTYGGNCARGTNATHYTNACNGARGCNYTNMGNATHCARTCNGCNAGYYTNMGNAGY AARGTNGTNGTNAARATGYTNAARGAYGAYGCNTCNAGYATHGARGARAARCARTTYATH GARGARGTNYTNCCNTTYMGNTAYYTNGAYCAYCCNAAYGTNYTNTCNYTNYTNGGNCAR TGYACNGARGCNMGNCCNTAYYTNTAYATHGTNGARCAYGCNCCNCAYGGNAAYYTNAAR GCNTTYYTNCAYCAYAAYAARAAYAAYGTNGAYCARYTNATGAARAARAARAARYTNYTN CARTTYTGYYTNGAYGCNGTNTGYGGNGTNGCNTGYATHCAYMGNCAYAAYTTYGTNCAY TGYGAYYTNTCNGCNMGNAAYTGYYTNGTNATGGGNGAYCAYMGNATHAARATHGGNGAY TAYGGNYTNGCNGARGARYTNTAYAARGARGAYTAYYTNCARACNAARTCNGARYTNYTN CCNYTNMGNTGGATGGCNCCNAGYYTNTGGAGYGAYATHTGYAARTTYGTNGTNAAYGGN CARTTYATHCCNGTNGGNGGNGCNTGGGTNGARATGGAYGGNAAYYTNCCNAGYGGNGAR GCNTGYATHMGNCARTTYYTNYTNGGNCARMGNTTYTTYYTNAARGARTTYGGNAARMGN TGYAARGARTTYTGGYTNCCNGAYACNTTYGGNTAYTCNGCNCARTTYCCNCARATHYTN MGNCAYTGYGGNATHACNMGNTTYYTNTCNCARAARYTNAGYTGGAGYYTNGTNAAYAAR TTYCCNCAYCAYACNTTYCARTGGGARGGNATHGAYGGNTCNCARGTNYTNGCNCAYTTY CCNCCNGGNGAYTCNTAYGARATGAAYGGNACNGTNAARGARYTNMGNAARTCNGTNAAY AAYTTYAAYGAYAARGGNMGNTCNAAYTGYTCNGCNTTYYTNTTYGGNCAYGGNGAYGGN GGNCAYGGNCCNAGYGARGARATGYTNGGNMGNYTNTTYMGNTTYAARGAYTGYGAYGGN YTNCCNAARGTNAARYTNAGYGGNCCNGAYGARTTYTTYTCNGTNGTNGARAARGARGAY YTNAAYATGYTNTGYMGNTGGMGNGGNGARYTNTAYYTNGARYTNCAYAAYGGNACNTAY ACNACNTGGGGNAARGTNAARAARTCNAAYMGNCARTGYGARATHYTNYTNCARGARATH GARGCNGTNTCNACNTAYGCNTGYTTYATHAARTCNACNTTYTCNTAYCCNTAYAAYGAR YTNAAYMGNYTNTGGAARYTNYTNYTNYTNAAYCARTTYCAYGAYGTNYTNCCNGGNTCN TCNATHTCNCARGTNTTYGARGAYGCNATGAAYATGTAYAAYGAYATHYTNCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TCNGAYCAYTGYAGYAARGAY GAYGTNAARGGNTTYGCNMGNYTNCCNCARGAYTGGGTNGGNGTNYTNCARTAYTCNACN GAYACNGARAAYTCNATHYTNGAYGARAAYACNTTYGAYTGYCCNYTNGTNYTNGAYMGN GTNAARAAYGCNYTNATGTTYGGNGCNTCNGCNATHATHATHYTNACNYTNAAYCARAAR GTNATHAARGARYTNGAYGCNTCNCARYTNGTNTCNMGNCCNATHATHYTNATGGARGAY GTNGARAAYATHACNGCNYTNYTNAGYYTNYTNATHACNCARGTNAARYTNCAYGGNAAR GTNATGATGAGYAGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGAGYGTNAARACNGCNTTYACNTAYAARGAR YTNGTNACNGCNACNAAYGGNTTYAGYGARGCNAAYATHYTNGGNGARGGNGGNTTYGGN GTNGTNTAYAARGGNCARYTNGGNAGYATHGAYTGYGCNGTNAARAARTTYAARMGNAAR GAYGARAARGGNAARGAYTCNAARGAYCARATHYTNAGYGARYTNACNGCNYTNTCNAAR TAYCARCAYAARAAYATGGTNACNYTNTAYGGNTAYGCNYTNGAYGGNCCNGAYYTNTGY YTNGTNTAYGARTAYYTNTCNAARGGNTCNYTNGARGAYMGNYTNATGMGNAARAAYAAY ACNCCNGCNYTNTCNTGGGARMGNMGNYTNAAYATHYTNGTNGGNTCNTGYMGNGCNYTN GAYTTYYTNCAYACNYTNGGNTCNGCNGCNYTNATHCAYGGNGAYATHAARAGYGCNAAY ATHYTNYTNGAYCARAAYYTNGARGCNAARTTYGCNGAYYTNGGNCARTCNMGNTAYGCN ACNTCNMGNTCNACN---ACNGGNACNYTNACNCAYATHACNCARGARCARACNGCNACN MGNGARTAYGGNACNMGNGCNTAYTTYGCNCCNGARATHGTNMGNGGNTCNMGNYTNTCN ------GTNCARTCNGAYATHTAYGCNATGGGNGTNGTNATHYTNGARGTNTGYAGYGGN YTNCARGCNTAYGAYTTYCAYAARCAYGTNAAYAAYYTNYTNACNGARTAYTAYTTYAAR CARATH---GCNAARYTNGAYGARCARGAYMGNGTNAARATHTTYCARGAYMGNGGNCCN GARGAYTAYATHGGNCCNACNACNTTYTCNTCNYTNYTNAARACNGCNGARYTNTGYYTN AARGAYMGNYTNAARAAYMGNCCNACNGCNGGNGARYTNYTNCARAARGTNACNGAYATH TAY--------------------------------------------------------- ------------------------GGNYTNAAYATHTCNGGNGCNGTNACNATHGCNAAR AAYYTNYTNMGN------AAYAAYCCNAAYGGNYTNTCNYTNGARGAYMGNATGTTYGCN GARCARTGYYTNGARTAY------------AGYCARGARGTNATGAAYGTNGARMGNAGY GGNGAYAARGARAARATGACNGTNATHYTNAARGAYYTNAAYTCNTGYATHAARGAYCAR GTNTAYTTYATHGGNCARGARTGYACNGTNGCNGAYGTNTTYYTNTAYCAYAGYTTYTAY CCNGTNTTYGARAARYTNACNTTYCARGARAARGARAARTTYATHCAYYTNTCNMGNTGG TTYTCNCAYATHCARGAYGAYGAYAARGCNMGNCARTCNYTNCARCCNYTNAARTTYYTN MGNACNATGYTNTAYACNGGNGTNTCNAGYCAYATGAGYTCNYTNGARACNGTNGTNTCN MGNYTNCARMGNATHGCNCCNYTNTCNYTNGCNGARAARTGGGAYAAYGTNGGNYTNYTN GTNGARCCNTCNGGNCCNAARTAYATHAGYAARYTNATGYTNACNAAYGAYYTNACNGCN TCNGTNYTNGARGARGCNAARGAYAARACNGTNGAYYTNATHGTNTCNTAYCAYCCNCCN ATHTTYGTNCCNYTNAARMGNYTNACNCARAARTCNTGGAARGARMGNATHYTNATHGAR TGYATGGARAAYMGNATHGCNGTNTTYTCNCCNCAYACNTCNTAYGAYGCNGTNCARGAY GGNGTNAAYGAYTGGYTNATHTCNGCNTTYGAYATHGAYAARMGNTCNATHTCNCCNGTN GARGCNTCNGARTCNTTYAAYAAYTGY---TCNCAYGTNYTNGARATHGAYTTYGARCCN GCNAAYYTNAAYGAYATHTGGAARACNGTN---ACNTCNTTYGTNCCNAARGARTCNMGN YTNAARAARGAYAARAGYTGYTTYTCNACNCAYGTNATHMGNACNGGNTCNACNGARAAR TGGMGNYTNMGNYTNGARTGYAGYCARTCNGARATGAGYGAYYTNATGAARGGNGTNYTN TGYTGYCARACNYTNGAYAARTAYGCNGTNTCNAGYYTNTCNAARGTNGCNGARAARAAY TGYGGNATGGGNMGNAARGCNACNYTNAARGAYTCNYTNACNYTNGARCARGCNGTNGAR TGYGTNAARAGYCAYYTNAARYTNAARCAYGTNAGYYTNGCNAARATHGARGGNGCNGAY AARAARGCNATHAAYACNGTNGCNGTNTGYGCNGGNTCNGGNTCNAGYGTNYTNAARAAY GTNAARGCNGAYYTNYTNGTNACNGGNGARATGTCNCAYCAYCARGTNYTNGAYGCNGTN CAYGCNGGNAGYAAYGTNATHYTNTGYCAYCAYAGYAAYACNGARMGNGGNTTYYTNTCN CAYYTNCARCARAARYTNAGYACNGTNATGGARAARTCNGTNAGYGTNTTYGTNTCNGAR ACNGAYMGNGAYCCNYTNGARATHGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYAARMGNACNGTNCARAAYAARAARACNTTY ATGTGYGTNMGNTCNTCNAAYTGYTCNATHAAYGTNYTNAAYMGNAARAARTGYCCNGCN TGYMGNTTYCARMGNTGYATGGAYATGGGNATGAARYTNGARGCNATHMGNCAYGAYMGN ACNMGNGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TCNMGNATHGARAAR TGGATHYTNAARTTYGTNCCNYTNCARCCNGGNGAYTGYYTNGGNTGYAARATHGTNGGN ACNTCNGTNTTYATHATHAGYGGNGTNATHGTNYTNACNTCNGCNATHGCNGGNAARAAR MGN------------------------------------------------------GAR AAYACNYTNAGYCAYGAYACNACNTCNYTNAARCARTAYTTYGAYAARTGGTAYYTNNNN ATGAAYACNACNAARNNNGTNNNNNNNGTNTTYCAYYTNAAYAAYNNNNNNNNNNNNNNN NNNNNNAAYATHNNNNNNGAYGGNAANACNYTNCCNNNNGAYNNNAAYCCNAARTAYYTN GGNGTNACNYTNGAYMGNCARYTNNNNTAYNNNNNNCAYYTNGARGGNNNNGCNNNNAAR ATHNNNAARMGNAAYTGYYTNNNNMGNAARNNNGCNGGNACNNNNTGGGGNGCNTCNNNN NNNNNNYTNMGNACNTCNNNNYTNGCNYTNTGYNNNAGYNNNGCNGARTAYTGYGCNCCN GTNTGG------ACNMGNAGYNNNCAYACNAAYYTNNNNGAYNNNAARYTNMGNGANTCN ATGNNNNNNATHACNGGNTGYYTNAARTCNACNCCNACNCARTGGYTNCCNACNATGAGY GGNATHCCNCCNCCNCAYYTNMGNMGNGARGARACNACNAARMGNATHACNGARAARYTN AARACNYTNCCNGAYAGYAAYCCNYTNAARATGGAYTTYTTYAAYAARGAYTCNGCNACN GAYCARCARGTNGCNGTNGTNGARMGNAARCCNCCNACNAAYYTNCARGARTTYYTNGAR GCNGARGGNYTNGARGAYTGGCCNYTNCCNATGAGYYTNGARGGNCCNYTNMGNATHGAR TCNGARGGNYTNTTYATHGGNAAYCARGARGAYATHGCNGARATHYTNAAYGARGCNGCN CCNYTNGGNYTNCARATGYTNGARACNATGGARGARMGNYTNTCNGCNYTNGARGAYAAR ATHAAYTTYTAYGCNAAYGARATHGTNACNAAYGARAARMGNCCNTCNMGNYTNGCNGAR MGNYTNTTYCAYTCNCCNACNAARACNTTYATGACNGAYATGTCNGAYTCNGAYGCNYTN AARTCNCAYMGNAGYTCNMGNGGNCAYAARAGYGTNGAYYTNATGGAYACNATGYTNGAR ACNMGNAARAARAGYYTNGAYTAYTAYGTNTTYCCNGGNTTYTTYCAYGGNGARTTYATH GARYTNCCNGGNCARYTNGARGCNCCNCCNGTNYTNCAYAARATHACNAAYGTNCARGAY TTYAAYCCNGGNTTYAARAARTTYTGGAARAARYTNTTYYTNTCNGARGCNTCNTCNGCN GTNYTNCARGAYGCNTTYTGGTGGATHTTYYTNGAYAARTTYTAYAARACNCARGGNTTY GARGARGAYAARGAYTGYYTNTTYGAYMGNATHTGYGAYAGYTAYGTNGCNYTNTTYACN AGYATHAAYACNGAYGTNAARGAYAARTTYYTNTCNGTNTAYCCNAGYTGYYTNTCNCAR GCNGTNTAYTAYACNTAYCARGARGCNTTYCCNGARTCNAARTGGMGNTTYGAYGARACN TTYAARCARTAYYTNGTNAAYYTNATHTAYGARTGGGTNACNGGNYTNMGNCCNGTNCCN GGNGTNTGGAARGCNTGGAAYGARGARGGNYTNGARGAYACNCARACNGGNMGNGARAAY GARACNGCNAARAARATGYTNGARGCNGCNGCNYTNAAYAARAARGTNGARATHAGYYTN GAYATGGAYTCNTTYGCNAARGTNATHGAYAARYTNGGNTAYGAYTCNGARGCNAAYYTN CARGGNCAYATGTCNMGNGARGTNACNAARACNTCNAAYMGN------ATH------TCN GCNCCNTCNMGNGGNMGNACNAAY---ACNGARTCNCAYCARATHGGNCCNGGNCCNGAY TAYGARMGNGTNAARTTYAAYACNTCNGGNMGNAGYCCNYTNATHGCNCAYTAYYTNCAY ATGMGNCARYTNMGNAGYTTYAARCARCCNGGNATGAARGTNMGNMGNACNGARATHYTN AARYTNCCNCCNGAYGGNCCNACNTAYCARCARTTYATHGCNGAYACNYTNAAYMGNGCN GAYACNYTNGARAARGARTAYACNMGNATHTGYGAYCARACNTCNTCNGCNATHYTNGAR YTNGARAARTAYAARMGNGAYTCNAAYAARGARATHGGNGARATGAARAARGCNYTNACN AAYATHAARACNATHCCNGARMGNMGNYTNYTNATGGARAARATHTCNGARTAYAARGAY YTNGTNATHAARGARAARCCNTTYTTYGARACNTCNATHTCNCARAAYGAYGTNAARACN TCNACNTAYTAYTCNTCNGAYGARACNTCNAAYYTNAARGCNTCNTGYCCNTGGAARTGG ACNTAYGAYACNTGGACNGARATHTAYCCNMGNTAYGTNACNCARGCNGARTGYYTNTGY ACNAAYTGYGTNAAYGCNGGNACNATGGGNTGYAARAARYTNCARMGNGARTAYCARTTY TAYYTNAARACNCAYTGYGAYGAYAAYAARCCNGTNTTYATGGCNTCNAARATGGARGTN ACNGTNGGNTGYTAYTGYAARTCNGTNGCNTAYCAYTAYGAYCCNAAYTAYTAYMGNYTN CCNCAYCCNGTNTTYGGNCCNATHATHGCNTTYYTNATGYTNTAYYTNGCNGTNGTNACN GTNTCNCCNAAYAGYATHCCNGARTCNTGGGGNCCNATHGCNCARTTYGCNMGNTAYATG TCNGCNTCNCAYTTYAAYTTYTGYATHGCNTGYTCNTTYYTNGTNATHGTNTCNCAYAGY YTNGARGCNGCNTAYGCNGGNAARGTNTGYAGYGAYMGNAGYTAYTCNGTNACNACNAGY GCNAARTGGGTNYTNTCNGTNTTYGTNATGGGNTTYCCNTCNYTNATGCARYTNTTYAAR CAYAARCCNACNYTNAARGCNACNGGNCARGTNYTNYTNTTYYTNGAYAGYCAYTGYGAR ATGACNAAYGGNTGGYTNGARCCNYTNYTNACNGTNGTNCAYAAYAAYCCNCAYACNYTN GCNGTNCCNATGATGGAYATHATHAAYCARGAYACNTTYYTNTAYGARGCNTCNTCNYTN GTNMGNGGNGGNTTYAGYTGGGGNATGCAYTAYCARTGGGARCCNYTNTCNAARGARMGN GCNAARGARATHGARTCNTCNCCNGAYCCNTAYGAYACNCCNACNATGGCNGGNGGNYTN TTYGCNATHAARMGNAAYTAYTTYTAYGARYTNGGNGARTAYGAYAARGGNATGGAYGTN TGGGGNGGNGARAAYYTNGARYTNTCNTTYMGNACNTGGCARTGYGGNGGNMGNATHGTN ATHGTNCCNTGYTCNMGNGTNGGNCAYATHTTYMGNAARMGNMGNCCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MGN GGNMGNGGNAARAAYAAYTAYYTNGCNGARGARGARGAYGTNGAYMGNATGMGNTCNMGN GCNGGNGARATHAAYGCNMGNTCNACNMGNAAYYTNTAYAAYYTNGGNCARAARGTNAAR CARYTNCARMGNGAYGTNTCNCARTCNGARYTNTCNAARCCNACNAARAARAGYCARATH ACNTCNCARYTNAAYGCNACNTAYMGNGGNGCNGTNMGNACNYTNCARACNTTYATHAAY CARYTNCCNTAYCARGAYYTNCARATGGGNYTNCCNTCNACNTAYAAYGARYTNGCNYTN YTNYTNMGNCARYTNACNACNATGATGACNYTNGTNCARCARGGNTCNAARGTNGARGGN AGYAAYGAYGTNYTNTCNYTNYTNGAYCARGTNGAYGAYTTYAAYTCNAARTGGTGYTCN YTNGCNYTNCAR---------------TCNAAYAARGGNYTNCCNACNACNCAYMGNMGN GCNTGGGTNAGYGAYACNAARGTNTCNAARAAYTTYCCNCCNGARGTNATHATHGCNAAR AARYTNGCNGCNAARAARCAYGCNGGNAARAARGARYTNCCNTCNTCNMGNCARCAYCCN AARGARMGNAARGCNGGNAARGARAAYMGNAAYYTNATHTAYGAYGARACNAARAARATG ACNYTNGCNGGNCARAARACNTTYGTNGARCCNMGNCCN--------------------- ---------ATHCAYTCNTCNAAYGCNATHTTYAARGAYATHGAYGTNACNAARGGNTAY YTNYTNCCNCCNGAYYTNCARGCNAARMGNGARAARGCNCARMGNGCNGTNGARYTNTCN TAYAARAAYTTYACNGAYTCNACNCAYTCNTCNMGNTCNAAR---GTNGCNGTNATGCCN MGNCCNAGYTCNGCNCCNTCNCCNYTNMGNAARAARGARGTNAAYTTYGAYYTNMGNGAR GAYAARAARATGTAYYTNCCNTGGATHCCNGCNGGNTGYGCNCCN------TGYAARCCN MGNCARMGNTCNTCNAGYGCNGAYTGYAGYCCNTTYTAYGTNMGNTCNATGGAYCARGAY GAYTGGTAYTCNYTN------TCNGARMGNCCNGARMGNAAYGCNGTNYTNCARGAYAAR CARMGNCARCCNGCNTAYGGNTAYMGNTCNYTNCCNACNGARMGNCARYTNMGNTCNTGY GAYGTNTCNGAYTCNTTYGTNGAYYTNATHGARAARMGNATHYTNTAYMGNATGYTNAAY AARAARGCNTCNTCN---------------GGNGGNMGNYTNTCNMGNAARGAYGAYGAR GCNYTNGAYATHACNGAYYTNACNGTNGAYAARTCNTAYGAY------------------ ---AAYACNAGYYTNAAYACNACNGCNGARGCNGCNGGNATGGTNGAYGCNCCNACNYTN GARAAYATHCARTTYAARYTNGARGCNATGGARAARACNMGNMGNGARATHMGNCARMGN TGGGGNACNYTNAARTTYATHGAYACNCAR---------CARMGNYTNAARCCNCAY--- ---ATHAAYGAYTGYCCNCARGCNCCNGCNGCNATHGAYTTYAAYAARACNTCNAARGAR ATHAARAAYTTYGARATGATHTCNCCNATHAAYAARGAYTGGACNGARGARCCNYTNYTN TTYACNAARCCNACNAARAARACNAAYTAYAAYTTYCAY---------ACNTCNTCNATG AARACNAARGARCAR------------------------------ATHGAYATHGAYCAR GGNTCNYTNGAYMGNATHTTYGARGAYMGNGAYMGNYTNGCNTAYCAYCAYMGNAARCAR TCNCAYCAYCCNACNGGNAARTTYAAYCCNTGGACNYTNATGGARCARATHTCNGARGAR ATHYTNAAYGARTGYATGCARGARGTNTCNGARGARGTNGARAARATHAGYGARGARATH GCNAAYCARATGTAYAARTCNGARTTYATGGTNACNGARCARCCNTCNGARTCNTTYGAY GAYGAYGAYGAYGAYAGYYTNTAYGGNGAYCAYYTNTCNAAYAGYTGYTTYGCNACNYTN MGNATGGAYMGNMGNGAYAGYGAYGAYTTYGAYGAYGAYYTNMGNTCNYTNGARTGGYTN CARAAYGARGAYYTNYTNAARAAYATHGGNGGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CARATGACNGTNTAYTCNGCNAAY ACNYTNTCNAARTCNAAYTTYTTYATHCCNAGYGCNCARACNTAYGCNAGYCAYGCNGTN TCNACNYTNGGNCARTCNYTNCAYACNACNGGNTAYTAYCCNCAYACNATHYTNYTNTGG ATH--------------------------------------------------------- ------------------------ATGGCNATHTCNACNACNTTYYTNATHGCNYTNATH GGNGCNGTNGGNYTNGTN------------------------------------------ ------CAYTGY------------------CARGTNGAYMGNGARMGNCCNGTNMGNATH GCNGARGGNTGYTCNGGNAARGTNATGGAYGTNTTYTTYYTNYTNGAYTCNTCNTCNTCN ATHTAYATHAAYGARTAYATGTCNCARCAYMGNYTNACNMGNGAYATHATHTCNMGNTTY GAYGTNAGYGARGARAGYACNMGNGTNGGNYTNYTNACNTTYAGYGAYGAYYTNGARMGN CCNGTNYTNAAYYTNAAYMGNTAYAAYAAYAARAAYGAYYTNYTNAAYAGYATHTCNGTN CARAAYYTNCCNTAYMGNAARGGNGTNACNAAYACNGAYCARGCNATHMGNTAYGTNMGN CARYTNAAYGARTTYMGNAAYGAYATHACNAARGTNATGGTNGTNATGACNGAYGGNGGN TCNMGNTCNCCNGCNGCNACNGCNMGNGARGCNGARYTNGCNMGNGCNGCNGGNTTYTAY ATGTTYACNGTNGGNATHGGNCARTAYYTNGARGARMGNGARTGGMGNGCNATHGCNAGY GAYCCNGAYGAYAGYTTYGTNTAYAAYATHACNTCNCCNMGNYTNYTNGARGARGTNAAR TTYTCNYTNCCNCCNMGNGCNTGYAAYYTNCCNCCNATHATHATHGGNGGNTCNTGYGAY GTNAGYMGNCCNTCNGARGTNTAYTTYGTNGGNGGNMGNAGYACNAGYTCNCARGCNGTN GAYGTNATHGARTAYTTYACNMGNMGNACNMGNGAYMGNMGNGAYYTNYTNMGNGCNAGY TAYTAYGTNGAYGGNTGYAAYCARGTNTCNAAYYTNATHYTNGTNGAYAAYGARCCNTTY ATHTGYGAYMGNTTYAAYGCNGARACNGGNGARCCNGTNGCNCCNAGYTCNACNGCNCAR ATGTTYMGNCARGCNGTNTCNYTNMGNAAYTCNMGNAAYCCNGAYACNAAYAARGTNATH GTNYTNTTYGCNGAYGAYGARATHYTNAGYCARGARMGNTTYGARYTNGCNAAYGCNGCN MGNAAYGCNGARAAYTTYGARGGNGTNACNGTNGTNYTNGCNGAYATGGGNATHMGNACN TAYMGNGAYTTYGCNYTNMGNATGGTNAAYAAYMGNAAYAAYATHGTNAAYTTYTCNAGY GGNAGYGTNTCNACNCARACNGAYGCNCARGCNMGNATHATHMGNGCNACNTGYGAY--- ATGGCNGAYAGYTCNAAYCAYCCNGAYYTNYTNTTYGAYAGYCAYCCNGARGGNTCNGGN TTYTCNAAYGAYGAYTTYGARAARGTNGAYGCNCCNGGNGGNGGNTTYGGNCAYGAYGAY YTNAAYGCNGCNGCNTCNGGNGCNTAY------GAYCAYGAYCARGAYGGNGARATHTCN ACNACNACNGAYGCNGAYGTNGCNGGNGARGARGARGARGARGARGAYMGNTTY------ ------TCNGCNTCNCCNGAYGTNYTNGCNCAYCAYCCNGARCCNYTNATHTCNTGGGGN GAYGAYGARGTNGCNYTNGAR--------------------------------------- ---GCNCARCCNTCNGCNCCNGTN------CCNGARAGYATHGARTCNYTNGTNAAYTTY ---GAYGAYAAYYTNACNGGNCARGAY------TAYTCNCARTCNTTYAAYTCNGCNCCN CCNACNAGYACNACNCCNGARCCN---AARYTNATHTCNACNCCNACNCCN---AGYAAY CCNATHTAYTCNCARYTNGAYGARTTYAARMGNGARGARAGYGARAAYGARAGYAARCCN GTNTCNGAYCARACN------GCNGTNGARACNGCNGARGGNTCNTGGATHAARGGNGTN GAYCCNMGN---GARGAYGGNGTNGAYGGNTTYTCNCARGCNYTNATHGAYYTNATHTAY TGGMGNGAYGTNAARACNACNGGNATGGTNTTYGGNGCNATGATGGTNGTNYTNYTNTCN YTNGCNATHTGYTCNYTNYTNAGYGTNGTNGCNTAYYTNTCNYTNGCNGTNYTNGTNGTN ACNTTYAGYTTYACNGTNTAYAARAARGTNATGAGYGCNGTNCARAARAGYAAYGARGGN CAYCCNTTYAARCARYTNATHGAYATGGAYATHACNYTNAAYGARGAYAARYTNAARTGY GTNATHCARACNGTNYTNAARAAYGTNAAYTGYACNGTNAGYGARYTNMGNMGNYTNTTY YTNATHGARGAYATGGTNGAYTCNGCNAARTTYGCNYTNYTNYTNTGGGTNATGACNTAY GTNGGNGCNTGGTTYAAYGGNATGACNYTNGTNATHYTNYTNGTNATHTCNYTNTTYACN YTNCCNAARGTNTAYGARACNTAYAARGTNCARATHGAYAAYTAYYTNGGNATGGCNAAR GCNCARYTNGAYCAYYTNATGGAYGTNGTNMGNAGYAARYTNCCNTTYYTNAARAARAAR GARAARGCNCAR------------------------------------------------ ---------------GTNCARATHATHACNGARCCNCARCARTTYTAYGARATHYTNAAR ATHAARACNAARAARGCNMGNAARMGNGTNACNTTYGCNTCNYTNNNNNNNGGNAAYGGN CARYTNGARAARGAYYTNGTNTCNTGYATHGAYGARGCNTGYCARGCNGCNATGGGNGAR CCNTCNTCNGARYTNGARGTNAAYGTNYTNYTNGAYTTYACNMGNGGNTCNMGNGGNCAR AAYAAYTCNMGNACNATGYTNCARCCNYTNATGAARAARTGGCCNAAYGTNCAYGTNGCN YTNTAYCAYACNCCNGAYYTNMGNGGNTGGYTNAARAARYTNACNCCNGARMGNTTYAAY GARACNATHGGNYTNACNCAYATGAARGTNTAYYTNTTYGAYGAYAGYTTYATHATHAGY GGNGCNAAYYTNAGYAAYGAYTAYTTYACNAAYMGNCARGAYMGNTAYATHYTNTTYAAY GAYTGYAARAAYATGTCNAAYTTYTTYCAYCAYYTNGTNAARACNGTNATGTCNTTYTCN YTNCARYTNGAYAAYAAYGAYGCNYTNCARYTNGCNCCNGAYTGGAAYATHCAYCCNTAY YTNGAYTCNGGNAAYGGNGAYGAYTTYAARGTNGCNGCNAARGARAARATHGAYCARTGY YTNMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNAAYCCNCCNYTNCARCCNTCNAAYGTNAARTCNAARAARTCNCCNAAR AARAARAARAARMGNGCNTCNCCNMGNAAYCAYYTNTCNTCNGCNAAYCAYTGYAARTCN GARCCNATGMGNCAYTAYMGNYTNAAYYTNGCNGARATHCCNTTYGTNGCNGGNAARTCN ACNACNGCNAGYCAYTCNYTNGGNGCNAAYGTNCARAARGTNYTNGCNATGATGAARTCN CAYAAYGCNGCNYTNTGYTCNCARCAYCCNCAYAGYYTNAAYAAYGARGGNCARMGNTCN GAYAGYTCNGCNTCNTCN---TCNGGNTCNAGYGTNATHTCNACN---GAYCARGAYYTN ACNGAYYTNYTNAAYCARYTNCARGARGARTTYMGNCARYTNAGYAGYGAYCAYCARGAY YTNGTNCARCARYTNGAYCARGCNYTNGAYAARGGNGARMGNYTNGAYYTNGARCARGAR ATHGARGTNYTNACNTCNMGNATGGARTCNAARGCNCARCARATHGAYAARATGMGNAAY CAYCAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TCN TCNTCNCCNTCNTCNTCNGGNYTNCARACNGCNGCNAAYAAYMGNAARCARMGNGGNATH GGNMGNGTNMGNGGNMGNCCNGARGARYTNGGNAGYGGNGCNGGNATHTCNTCNTCN--- TCNTCNGCNTCNAARACNTCNYTNACNYTNCCNAARTCNYTNGCNGCNTCNTCNTCNGCN ---------CCNAAYGCNGCNGARGTNACNMGNMGNGGNTCNCAYYTNAARGGNCCNGGN ---------------------------GAYAARTCNGGNMGNYTNTCNGCNTAYGAYTTY CCNGAYGAYAGYCCNGAYGARGAYCCNGTNAAYTAYATGGCNYTNACN------MGNACN GGNMGNAARTGYCCNGTNGAYAGYTCNGARAAYAAR---AGYTCNTGGACNGGNCCNGAY ACNCARGGNGGNGARACNGGNAGYGGNGAYAARAAYGARGCNCAR--------------- ---------CARGCNCAYGAYACNTCNTCNGGNTTYGCNAARCCNMGNTTYGGNAGYMGN GTNAGYAGYCAYGARGCNGAYGCNGGNGTN---------TCNGCNGTNGAYAGYACNMGN CCNGAYAAR------GGNCCNGARTCNGGNGARGTNGAYAGYTCNACNTCN---TCNTCN TCNCCNMGNGGN---------AARGGNYTNGGNCARTCNTCNGARGTNGGNGCN------ ------------------GGNAGYCARGAYTCNYTNGTNGCNGGNAGYGARGAYGTNGGN GGNTCNTCNAAYCARTCNGTNGCNAGYCCNTCN---------------------TAYTCN GCNGGNCARCCNGTNGTNTCNAGYATGATHMGNGAYCCNGARCARACNACNATGTGYTCN MGNGAYCARGARCCNACNCCNYTNYTNTCNGCNCARTAYGARACNYTNTCNGAYGAYGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARGARYTNGARGAYAARGCNGAYAAYGCNGCNYTNGARGTNGTNATHGAYAAR YTNYTNGARTCNGGNCARAAYTGGGTNACNGARGCNGCNAARGCNCARGTNGAYGTNGCN AARGCNACNAARCAYCAYAGYTCNYTNYTNAARAARGCNATGGAYGARACNACNAAYATH YTNGAYAARGAYTCNGARTGGAARGCNGTNACNGTNGCNTTYAARGARMGNGARAAYGCN GTNGCNMGNGCNAAYGARYTNGTNGAYGARGCNMGNAARAGYGTNGARAARYTNAARMGN GTNATHGAYGARGCNAARTCNAAYAARGTNACNATGAARAAYAARGTNATHCAYGAYGCN ACNAARAARYTNTCNGAYTTYAGYAARGARATGTCNGTNGCNGGNGCNCARGTNMGNCAR GCNGAYGCNGAYGCNAARGTNATGYTNAARTAYAARGAYYTNGTNGAYAARGGNMGNAAR CARTTYCARGAYGARYTNAAYAGYYTNYTNCCNGAYGTNAARMGNGGNMGNAGYAGYMGN AARYTNTCNGARGARGARYTNAAYGCNYTNATHGCNCAYGCNCAYMGNMGNATHGARCAR YTNCARAARCARATHGCNGARCAYYTNTCNACNGARCARAARMGNATHACNTCNGCNYTN GARGARCARAARGTNGARCAYCARAGYYTNACNCARTCNGCNATHAAYGAYGARMGNGCN TTYYTNTAYCARGARTTYGARATHGARMGNCARAARATGGARATHGARTTYTCNGCNTGG ATGGARGCNGAYGTNMGNAARCARYTNAGYMGNCARGCNGCNGCNCAYAGYGAYCAYYTN AARGAYGTNYTNGCNGTNCARGARGARCARYTNAAYAARGAYAAYGARMGNAARATGAAY ATHAARYTNYTNGARGARMGNGARAARTTYCARACNGARACNGCNGGNTGGATHTCNMGN YTNAARGGNATHGARGCNGCNGTNGAYGCNMGNGCNGCNAAYGARAARYTNGCNCAYACN GCNCARGAYYTNTGGYTNGCNTGYATHGCNYTNAAYTCNACNATHCARTTYGGNGAYGAR GARGARGGNCARCCN---ATHCCNYTNAAYCARCARGTNAARACNGTNATHAGYTCNTCN GAYAARCAYCCNTTYGTNGARACNGTNGTNAARTCNATHCCNCARACNGCNYTNGARMGN GGNATHTAYACNGARAAYGCNYTNAARGAYMGNTTYACNAARGTNTCNCARGTNAGYMGN MGNYTNGGNYTNGTNGARGAYACNAAYGCNTCNYTNTAYAARTAYYTNATHTCNTTYGTN CAYTCNTTYTTYACNGTNAAYCAYGTNGCNGCNTAYTCNGARAARGAYYTNGTNTCNYTN GAYGARATGGAYAAYTTYAARYTNYTNTCNAAYGCNCARTAYTGGATGGARAARGGNAAY YTNGAYYTNGCNGTNMGNTTYATGTGYCARYTNACNGGNCARTCNMGNATHGCNGCNAGY GAYTGGATHGAYGARGCNAARYTNYTNYTNGARACNMGNCARGCNGCNAARACNATHYTN TCNTTYGCNTCNGCN---------------------GARGAYYTNAAYGTNATHGARYTN YTNTGGAARCARGAYGTNGAYYTNGGNGTNGGNAARGARGTNTAYGAYCAYTCNYTNMGN GARGARYTNGARMGNAARCARGARCARGARTAYYTNAARCARCARGARCARMGNAARGCN CARYTNGCNGCNMGNGARAARGARGARYTNAGYMGNCARYTNGARGCNAGYMGNTGGYTN AAYCARAAYTAYTCNMGNGAYGGNGARACNGGNGARTGGGTNAARMGNCARAAYMGNCCN TTYACNAAYGGNGARTCNGCNGGNACNAAYMGNGCNGARACNGAY---------GARGTN YTNACNYTNGARGCNGCNYTNGAYTAYYTNTCNAAYAAYGTNGTNGCNAAY--------- ---AGYAAYYTNGARGTNAAYACNGAYMGNGTNGTNCCNGTNCCNGAR---------ACN TCNTTYCARYTNGAYAAYGAYGTNGAYGAYYTNCARGCNACN---ATHACNGTNCARGGN YTNCARGCNGARAAYYTNTCNCCNGARCAYAGYCCNMGNYTNGARAAYCAR--------- ------TGGTTYGARATGGAYCARTAYYTNAAYGTNTCNYTNCCNGAYTCNATGCCNGAY YTNAGYAAYGAYYTNGGNYTNYTNCCNCAYGARTAYGARGTNGAYGAYTCNTCNAARYTN GAYATGYTNAAYCCNATGYTNGAYYTNGAYCARCAYCARACNGAYAAYYTNYTNACNAGY TCNGAYATHYTN------------------------YTNYTNCARAAYGCNTCNYTNCAY GCNGAYGAYCARGAYAAYGCNTTYGARYTNGGN------------------------AAY GTNACNYTNACNAAYYTNAGYGGNCCNTGYAAYATGAAYACNTCNYTNGAYTGGGARTCN GARGAYATHCAYYTNTTYGAYAAYYTNACNACNYTNCCNCARGGNAGYATHGAYGAYGTN GAYYTNCARGGNGTNGARGAYYTNTTYYTN---------ACNACNGARGCNTCNGAYYTN TTYACNGCNACNACNGARGCNTCNGAYYTNTTYACNGCNACNACNGAYYTNGGNGAYGCN TCNAGYATHGARATG---------GCNTAYGARGCNGARGGNYTNGCNYTNCCNACNAAR TCNTTYGCNGARGAYYTNAAYGAYACNTTYGAYGGNYTNGARGGNGCNACNGGNGGNGCN GAYTAYAGY------------------AGYCCNCCNTAYMGNAARATGTCNMGNYTNTCN GARTCNTCNTCNGAYTCNGGNTTYGGNGGNAARGGNGCNTTYAGYTCNTCNTCN------ ---TCNTCNTCNTCNTCNTAYGCNGGNAGYCCNGCNGAYAGYAAYYTNYTNAAYAAYGAR ACNAAYTCNAAYGAYACNGAYCAYGAYCCNCAYGGNAGYAARGTNYTNGCNCAYCARGTN GCNCAYAAYCAYACNTAYAAYACNYTNCCNGGNCAYACNCCNMGNGARGTNAARAARTAY GCNCAYAARGARCCNTCNAARAARGGNCCNCARTGYMGNGAYGCNMGNMGNGCNCARGAR YTNAARATHCCNTTYACNATHGARGARATHGTNAAYTCNCCNGTNGARACNTTYAAYGAR ATHYTNACNAARTAYAGYYTNACNGARGAYCARYTNACNYTNATHMGNGAYATHMGNMGN MGNGGNAARAAYAARYTNGCNGCNCARAAYTGYMGNAARMGNAARGTNGGNGTNATHGTN ACNYTNGARGAYGARATGGTNGARYTNCARAARGTNMGNGAYMGNYTNMGNGCNGARMGN GCNGCNATGGAYAARGARTCNMGNATGATGAARGARAARTTYTCNCAYYTNTAYTCNCAY ATHTTYCARTCNYTNMGNGAYGARCAYGGNCARCCNTAYAAYMGNAAYAAYTTYTCNYTN CARCARTCNAGYGAYGGNAAYATHTTYYTNGTNCCNMGNAAYATGAGYATGAAYATGAAY AGYACNAGYYTNCAYTCNAAYGGNTCNAGYCCNGGNAARGGNGCNGGNCARGAYAAYGAY CAYAGYGTNATHAARAAR------------------------------------------ ---------------------------------------YTNATHAARAARGGNCCNAAR AARATGTTYTAYAARAARAARMGNGAYCARGARCCNGCNGCNYTNMGNGAYCCNGCNTAY GGNGARCAYGGNTAYYTNCAYYTNGARGAYGTNMGNATHCAYTAYGTNGCNAGYGGNCCN TCNGAYAARCCNYTNTTYYTNTTYYTNCAYGGNTTYCCNGARTCNTGGTAYTCNTGGMGN TGGCARATHAARGARTTYAAYCARGAYTAYMGNGTNGTNGCNATHGAYATGMGNGGNTAY GGNGAYTCNAGYCARCCNYTNGGNATHAARMGNTAYAARATGGARTGYATGGTNAARGAY GTNAARCARATHATHACNGCNYTNGGNTAYAGYTCNTGYATHYTNGCNGGNCAYGAYTGG GGNGGNGCNATHTCNTGGGCNTTYGCNGGNTGYCAYCCNGARYTNGTNGARAARGTNATH ATHATGAAYAGYCCNCAYGCNYTNTGYTTYAARAARTAYYTNCARACNCAYTGGGCNCAR TTYAARAARAGYTGGTAYATGTTYTTYTTYYTNGTNCCNYTNYTNCCNGARATHTAYYTN MGNYTNAAYGAYTAYAARCCNTTYGAYYTNATGTTYAARAGYAARAARAAYGGNGTNYTN ACNGAYGCNACNACNGCNGARGAYGTNGARGTNTAYAARTAYYTNTAYCCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNAARGAYAARAGYTCNAARGTN AARGTNCCNTCNMGNYTNGCNAARGCNGTNGCNGARAAYMGNTCNYTNTTYGARAARTGY TCNACNGCNCARYTNGTNMGNMGNACNMGNAARGARGAYACNGCNGCNGTNTTYGTNAAR MGNYTNGARGARTCNAAYACNATH---AGYCCNGARYTNTAYGCNMGNGCNAARGCNYTN TCNTGYYTNCARAGYCAYGARYTNATGATGCARTCNYTNCARTCNYTNAARATGGARCAR ATHACNGAYACNACNCCNTTYGARACNGCNTTYMGNACNAARMGNYTNYTNGARTTYATH YTNTCNAARTTYGCNCARTGYCARGAYGARACNGAYTAYTTYACNMGNGTNCARTTYAAR TCNYTNCCNACNGARCCNGCNTTYGTN---TCNGCNGARGAYAAYAAYAAYGTNGTN--- ------AARTCNYTNTTYGTNAARCCNGAYAARGARYTNAARGARMGNAGYGAYATGYTN GAYGCNYTNGCNAGYTCNMGNGTNTGGACNMGNYTNCARTTYGARAARAAYATHTCNYTN YTNMGNCARCAYATHATGTCNYTNTCNGARAARGARTGGTGGGARATHYTNGCNCARGAY CCNMGNAAYGAYACNGTNGTNCARYTNGTNCAYAGYYTNYTNACNTCNACNGGNGARTTY TGYACNGCNGTNGTNAARAAYCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYYTNAARAARATGATHAARCCNAAR CARYTNACNCCNYTNMGNAARCARGTNAARGARAARGCNACNAARGARCAYGAYTGGGAY GAYCAYYTNATGTCNMGNYTNAGYAARYTNACNGCNAAYTGGATHGTNCAYCARMGNATG CCNGGNGAYAARACNAARGARAARYTNTCNAARGTNYTNGARTCNTGGTAYGGNATGCCN ATHCAYACNGAYYTNGTNMGNGARGARGTNAGYGAYGGNGARGAYGARGAYGCNAARAAR GCNAARAARCCNAARTCNAARTGGMGNAARAARGARGCNGCNYTNYTNGARMGNGTNTAY AAYGTNACNCCNCCNCCNGTNGARGCNYTNGAYCCNTAYTCNGAYGAYAGYMGNGCNCCN TTYTAYMGNCARCCNGCNGGNATHMGNAARAARAARAARAGYGARGARAARGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CARCARYTNAARTAYATHGGNCAYYTNCAYCCNAGYCCNAGYATGATH TTYGCNGGNGGNGCNAAYGAYCAYTAYGTNMGNAGYGTNGTNTTYTCNCARAAYGCNGAR ACNYTNGGNTCNGTNTGYGAYGAYGGNTAYGTNMGNTTYTGGAAYYTNGGNGTNAAYGGN GAYCCNYTNTCNATHGCNAAYATHGARGAYATHATHTGYTGYAGYTTYTCNGAYGGNGGN GGNGTNYTNGCNGTNGGNTGYMGNAGYGGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNATHMGNCCNACNTCNAGYATGTCN CAYACNGARAAYGARGAYYTNGARGARTAYCARGAYYTNTTYAAYGAYGARCCNGARGAY GARGARGGNMGNYTNGTNCARTCNATHATGAARACNACNYTNAARAAYAARTCNCAYGGN AGYAAYGAYGCNACNTTYAAYTCNAARACNCARACNTCNCAYTCNTCNGAYACNGGNTTY AARACNGARAAYGGNTTYTCNTCNACNCAYTGGGCNGARGGNGARAAYCARMGNACNCAR MGNCCNYTNTCNGCNMGNTCNACNMGNTCNGTNACNTCNAAYAAYMGNATGACNMGNGTN CCNATHACNTCNCAYGAYCARAARMGNATHACNTAYAAYGGNGAYGTNATHGARAARMGN GCNTAYTGYTTYACNGARCCNGAYMGNCCNTTYACNCCNMGNACNYTNAARAGYAAYTCN CARTCNMGNATHAARAGYTCNAAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHMGNCCNYTNAARGARAARGTNACNGARATGATH------ ---GGNGARYTNGCNAARTTYGARAAYATGGCNGGNAGYGTNAARATHACNGAYGARGCN YTNAARGARGAYGTNTTYGGNCARCCNCARMGNTGYGCNTGYYTNGTNGCNCARYTNTCN GCNACNGAR------GARATHGTNGGNTAYGCNYTNTAYTAYAAYGCNTAYTCNACNTGG GTNMGNACNTAYGTNCAYYTNGARGAYYTNTAYGTNAARCCNGAYTAYMGNGGNAARGGN ATHGGNAARAARATGTAYCARGCNGTNACNAARATGGCNYTNACNAAYGGNTGYCARMGN YTNGARYTNGARGTNYTNGGNTGGAAYAARCCNGCNAARCARTTYTAYGARAARGTNGGN AAYCARGAYYTNACNGARGCNGARGAYTGGCAYAARATGMGNATGAAYCARACNACNATG GARAARTTYATH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CAYCAYCAYCAYCAYCAYCAYCARTCNCCNMGNCCNTTYGTNCCNAAY GTNTCNTCNTCNTCNTCNTCNTCNYTNATGCARCARAARAAYGARAGYATHTCNCARYTN GARAARCARYTNGARAARGARCARGARGARAAYMGNMGNYTNAARYTNGARATGGARGAR AARGAYMGNAARATHGCNGARYTNCARAARTCNGTNGARYTNYTNAAYAAYGARTGYGAY GGNYTNGAYGARGAYAAYYTNAARYTNCARGARGARAAYAARGCNYTNATHMGNGCNATG GCNAARYTNAGYTCNAAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG TCNTCNACNACNCAYTGGGGNGARATHCCNAARATHCARGAYACNGAYYTNGGNATHGCN GCNYTNGARMGNGARCARATHACNAARCCNAARCCNATGGAYATHGARGGNCAYYTNYTN CAYCARCCNTCNAAYMGNCAYTAYCCNCCNACNAAYGARATHYTNTCNAGYGARTGYTTY AARATGGAYCCNGTNGTNATGCAYACNATHMGNYTNYTNCARCAYATHAARAARGTNAAR ACNGCNGTNGARATHYTNCARAAYGAYATHAARACNGAYATHGARCAYACNTCNATHAAY YTNGGNYTNATHCCNGARYTNGAYMGNCAYCARATHAARGAYMGNTCNTGYCARAARTAY TGYACNCARGARGARAAYGARAGYGAYTTYATHMGNGGNATHTCNAARCCNCARCCNCCN ATHGAYGARTCNACNTGYMGNAARYTNYTNMGNMGNTCNACNGCNGCNATHTGYGCNCAY YTNGCNATHGAYACNGCNCARGARTCNGTNYTNGAYACNYTNACNGAYATHTGYCAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GTNTCNGCNCCN GCNGGNGTNTTYMGNGGNYTNATHYTNAARTCNTTYAGYGGNYTNCCNTAYGTNGGNTAY MGNGGNATHCCNTTYGCNYTNCCNCCNATHGGNAARYTNMGNTTYGCNMGNCCNGTNCCN CAYCCNAARYTNGARGGNGTNTAYGAYGCNACNCARGARGCNTCNGTNAGYATHCARCCN GTNGGNGTNATHYTNGGNCCNTGGAARCARGARGAYTGYYTNTAYYTNAAYGTNTTYACN CCNGTNAARGAYAAYTCNCARGARAAYACNCCNYTNAARAARGTNATGGTNTTYATHCAY GGNGGNGCNTTYTTYATGGGNTGYGCNAAYCARCARCCNCCNGGNGAYYTNGTNTCNCAR NNNNNNNNNATNNNNNNNNNNYTNAAYTAYMGNYTNTCNTGGYTNGGNTTYGTNAARGGN CCNACNGAYGARATHAAYGGNAAYATGGGNYTNTGGGAYCARYTNGARGGNYTNAARTGG GTNCAYGCNAAYATHMGNTCNTTYGGNGGNGAYCCNGAYGAYATHACNYTNGCNGGNCAR TCNATGGGNGGNGARAGYGTNTCNGCNTTYAGYGTNATHAGYCARGCNAARAAYYTNTTY ACNAARGGNATHYTNATGAGYGGNACNATGTTYGCNTGYMGNTCNACNTTYGGNTCNTCN GAYGTNYTNYTNGAYTGGYTNGTNAAYAARACNAGYYTNTCNCAYTCNCAR--------- ---YTNATHCARGARYTNAARGAYYTNCCNCARGARMGNTTYGTNYTNCCNGTNCARAAY GARATHACNAAYAARTTYACNACNATHGAYAARGARYTNTTYCCNGCNTCNTTYCCNGAR ATGATHGCNGAYAARGAYTAYYTNAAYAARGTNGGNTTYTTYGAYMGNGAYTAYYTNGTN ACNYTNACNAAYAAYGARGGNCARYTNGCNCARACNGGNYTNTTYTCNTGYGAYGGNGAR GGNATHAGYGCNGARMGNYTNAAYCARTCNGARGARYTNYTNCARAARYTNATHAARTGG TAYAGYCARGARGGNCAYCAYTGYATHAAYCCNGTNAAYGAYATGTTYAGYGAYCCNATH ATHTGYYTNCCNACNTTYGAYTTYYTNAARGTNGCNACNGAYCARCAYAAYTCNTAYTTY YTNYTNTTYGAYCAYTAYCCNACNTAYGCNCCNGCNGAYGCNGCNGGNACNGTNCAYTGY ATHGAYYTNTGYTAYYTNTTYGAYATHCARCCNAAYGARATGTAYCARATGATHAAYGGN YTNTCNACNAARAARGARTTYACNGARGARGAYAARAARATGAARAARATHTGYATHGAY YTNGTNGTNGAYTTYATGCAYAAYGGNAAYTGYAARAARTCNTCNAARACNCAYGTNGGN AAYGARTGGCARCCNTTYGARCCNAAYAARGARTTYTAYYTNAARYTNACNCCNCARCCN ACNATHGGNCARTTYCCNTAYATGGARMGNMGNAARYTNTGGGARACNGTNGTNCCNGAR TGGAARAARGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATGCAYCCNTAYTAYTAYGTNCARTAYGTNCCNATHCARYTNAARCARGAYCCNGAR ATGAARGTNAAYTGGGCNGCNTCNCCNAGYACNGCNCCNAARCARGAYACNAGYAARCAY TTYCAYGTNTTYGTNGGNGAYYTNAGYTCNGAYATHGARCARCAYCARYTNMGNGARTCN TTYGCNGGNTTYGGNGARATHTCNGAYTGYAARATHATHMGNGAYCCNAAYACNATGAAR TCNMGNGGNTAYGGNTTYGTNTCNTTYGTNAAYAARCARGAYGCNGARGTNGCNATHAGY CARATGAAYAAYCARTGGYTNGGNACNMGNGTNATHMGNACNAAYTGGGCNTCNMGNAAR CCNYTNGCNCCNGTNGCNAARGARAAYACNAARCCNYTNGCNTAYGAYGARGTNTTYAAY CARTCNAGYTCNACNAAYTGYACNGTNTAYTGYGGNGGNGTNACNAAYGGNYTNACNGAR GARYTNATGMGNAARACNTTYTCNCARTTYGGNACNATHCARGARGTNMGNGTNTTYAAR GAYAARGGNTAYGCNTTYATHMGNTTYAGYACNAARGAYGCNGCNGCNCARGCNATHTGY GCNGTNCAYGGNACNACNGTNAAYGARCARTCNGTNAARTGYTCNTGGGGNAARGARTCN AAYGARGGNGGNCCNACNAAYCARCARTCNAAYAGYCCNCCNGTNGTNATGYTNCARTCN CARCARCARCARCCNATHGCNGCNACNCCNGCNGCNGCNCARTAYGGN---CARTTYTAY AAYATGAAYTAYTAYCAYGGNACNCCNTAYGCNGCNGGNACNCCNACNTAYCARAGYGCN ATGCCNGCNCARGGNCARTTYATHCCNGCNGCNGCNGGNCARTGGCCN---GGNTAYTCN AAYTAYCARGCNTAYGGNAGYATGAAYGTNCCNGTNGGNCARTAYGCNGGNYTNCARATG CARCCNGGNGCNCARCARCARCARTTYAGYGGNCARACNCARGGNATGGTNGGNTAYCCN ATGCARCARGGNATGGCNMGNTCNAAYGTNMGNTAYGARGTNYTNCCNTCNGARGARCAR AAYGTNGCNGCNGARCCNGTNAAYATGGCNATGGTNATHCCNCCNCCNAGYTAYACNGAR AAYGCNGTNATGGARCARGAYGGNGAYGAYCCNGCNTTYGGNCCNGCNAARYTNCCNAAY TAYGTNGARGCNACNACNYTNCCNTCNTAYGARGARGCNGARMGNACNAARGCNGARCAR GCNGCNGCNTCNAGYACNAGYAAYAAYGAYTGYGARGCNGGNMGNYTNATGAGYATHGAR GGNGTNAAYGARACNACNATHGGNACNGAYGGNATGTTYATGTGYACNTTYTTYATHTCN TTYYTNTTYAAYTGGYTNGGNTTYYTNYTNTCNYTNTGYYTNTCNAAYACNATHGCNGGN MGNTGYGGNGCNYTNTCNGGNYTNGGNYTNTCNATGGTNAARTGGGTNGTNATHGCNAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TAYTCNGTNYTNTTYYTNCAYGGNATGMGNTTYTCNTCNAARAAY TGGYTNGAYATHAARTCNYTNTTYCAYGTNGCNAAYTGGGGNTGGAARGCNGTNGCNGTN GAYYTNCCNGGNTAYGGNCARACNACNGAYAARATHGARGAYAARCAYAAYACNGAYTTY YTNTCNTCNYTNGTNACNACNYTNGGNYTNAARAARCCNGTNATHGTNTCNCCNTCNATG AGYGGNACNTTYTCNYTNCCNTTYYTNTTYGCNGGNGGNGTNAAYAGYYTNGARMGNGCN YTNGGNTAYGTNCCNGTNGCNCCNGTNCARACNGGNGCNTAYGTNGCNAAYTAYCCNCAR TGYATGATHCCNACNYTNATHGTNAGYGGNTCNAARGAYMGNAGYATHGGNATHACNAGY AAYAAYCAYYTNAGYAAYYTNCCNAAYGGNATHYTNGCNTCNATHGARGGNGCNGGNCAY GCNTGYTAYYTNGAYAAYCCNGAYATGTTYCAYAARTAYYTNTAYCAYTTYYTNAARGAY YTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNGAYGGNTAYGARATGCCNACNGGNACNATHGTNGCNGTNCAYATHTGGAAYYTN CAYCAYAAYCCNCAYGTNTGGGARAARCCNGARGARTAYGAYCCNGARMGNTTYTCNCCN GAYAAYTGGGCNAARATGGAYCCNTTYCARTAYATHCCNTTYTCNGCNGGNACNMGNAAY TGYATHGGNCARAAYTTYGCNATGAAYGARGTNAARGTNATHYTNTCNTCNGTNATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARGCNAAYGARAAYGTNAARAAYYTNAARACNGARACNGTNGCNTGGAAR AAYMGNTAYTGYYTNTCNMGNGAYGARAGYGAYMGNATGYTNGARGARAAYMGNAARAAR GARGARCARATHCARACNYTNACNGTNCARYTNCAYGARACNYTNCARCARACNYTNGCN YTNCARAARGCNYTNTTYACNAGYTGYGARMGNGARAARTGYAARGARGARGTNATGAAY TCNYTNMGNAARCARCARAARMGNACNATGCARGARATGGCNAGYYTNMGNAARYTNTAY GARMGNCARTCNAARGAYYTNACNYTNTAYCAYYTNAGYGTN------------------ ------------------------------------------------------------ ---------------------------------------------------------TCN CARGARCANGARYTNGAYATGGTNAAYMGNGAYCCNAAYAAYYTNAAYGAYCAYGTNMGN GTNTGYTTYGAYGARGTNTTYGGNGARCCNGAYGGNGCNCAYTCNATHAAYTGYGTNTGG AARAAYTCNTAYMGNTGYTTYAAYTGYTGGAARAAYTGYTGYTAYAAYYTNYTNACNATH YTNTGYGCNATHCCNATHGCNATGTGYTGGGGNTGYGARTTYGCNTTYATHACNTTYACN CAYGTNTGGCAYGTNACNCCNTGYATGMGNTCNTAYATGATHCARTGYGGNTGY------ ------------------------------------------------------------ ---------------------------------CARMGNAAYMGNGARGARGARYTNMGN ACNCARTGYATGGAYGTNGARACNCARYTNAGYCAYAARCARAAYGAYGTNGARMGNYTN GARAARATGATGGARGTNATHAARCARGARTGYAAYYTNCARGTNGTNGAYAARATHGCN AGYGTNGARMGNMGNYTNATHCARCARYTNGARGARAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ACNAAY TGGAAYCARGARACNAARTCNMGNYTNAAYGARAARGTNACNTCNAAYGTNAAYGAYYTN GGNTCNYTNATHMGNCARGTNATHMGNGCNTCNAARACNAAYGAR--------------- ------------------------------------------------------------ ---------------------------TTYYTNGCNCARGCNGCNAARGGNTGYTCNACN GARACNATGAARAARATGAAYGTNGTNAARTCNCARGCNTCNATHTCNMGNAGYYTNCAR TTYYTNGAYGARGTNCARGAYCARYTN---------------------------GCNYTN GARTGGTAYYTNAAYAAYYTNGCNMGNCCNAAYGAYCAYGTNYTNYTNTTYCAYTGYTCN CARTTYGARYTNCAYGTNGGNYTNCCNGGNATHGCNGTNAAYGTNGARCAYGTNAGYAAR CARGTNCARGARGCNAARGCNAARGCNGARYTNATHTGYAGYAARGCNGCNGARYTNYTN MGNCARMGNTCNATHCARTGYTAYTCNATHATHGARAGYMGNGCNAARCCNCAYGARGCN ATHYTNGARGTNATHCARMGNGARAARGTNGAYTAYGTNGTNATGGGNACNMGNGAYYTN GGNTCNGTNAARMGNGCNYTNGTNGGNAGYGTNAGYACNGAYGTNGTNMGNCAYGCNAAY GTNCCNGTNACNGTNGTNAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARMGNACNATHMGNTTYAAR GGNACNMGNTAYMGNGARATHAAYMGNMGNATGGARAARTTYYTNAAYAARAARAARGAR TTYCCNGAYTTYCAYGAYGTNAARACNATHATHAARYTNACNAAYAARAARTGYGAYYTN CARATGAGYTCNCARCARGTNAAYGAYGTNGCNMGNGARGCNTTYGTNGAYGTNGGNGAR ATGYTNCARACNMGNMGNCAYCARGAYTTYATHGCNACNTTYGGNTCNCARCARACNGAY GGNTAYACNGAYCCNGCNYTNACNGAYCCNGARYTNMGNAARAARYTNGARAGYAAYMGN AARMGNAARYTNGTNACNCCNACNTCNAGYYTNGARATHYTNGAYGGNGAYAARGAYGTN GTNGGNGAYTTYTAYGAYGGNMGNTCN---------TCNCARGCNTCNGARMGNTCNTGG TCNMGNGCNAGYGCNGGNTCNATHCCNCCNMGNAAYGAYTCNTCNYTNGGNMGNMGNATG GTNACNCCNACNAARCARGTNTCNYTNCARGCNGTNMGNMGNAARGARGARAGYTCNGAR CCNTTYGTNGAYCAYATHCARGGNGCNAAYTCNMGNACNGARGCNAGYMGNMGNACNGCN TGGGARATGGARGCNGCNGAYGAYGTNGAYTTYTCNAARACNGGNGAYAAYMGNMGNAGY AAYAARGGNMGNCARAGYTTYGTNAAYGAYGCNACNCARCARACNAAYCCNGGNCARACN CAYACNTCNACNTCNGARCCNCARACNCAYCARCARCAYAAYACNCAYGTNATHGAYAAY AARAAYMGNYTNAGYTCNAGYTCNGAYGARGAYGAYGAYGAYGAYGAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TCNAGYMGNYTNGCNTGGTTYGAYYTNGARATGACNGGNYTN GAYATHGAYAARGAYATHATHYTNGARATHGCNTGYYTNGTNACNGAYAARCARYTNAAY GTNGTNGCNGARGGNCCNGAYYTNGTNATHCAYCARAGYGAYGCNGTNYTNAAYGGNATG AAYGARTGGTGYATHGARCAYCAYGGNAARTCNGGNYTNACNGARGCNTGYAARAAYTCN AARATHAGYATGCARGARGCNGARAARATGGTNYTNAGYTTYYTNGARCARCAYATHMGN AARGGNGTNTGYCCNATHGCNGGNAAYTCNGTNGGNACNGAYAARCARTTYATHGCNAAR TAYATGCCNYTNYTNTCNGAYTAYYTNCAYTAYMGNATHGTNGAYGTNAGYACNGTNAAR GARYTNTGYMGN---------------------------------MGNTGGTTYCCNGAY GAYTTY---AARTCNGCNMGNAARAARYTNGCNCAYMGNGCNATGGAYGAYATHMGNGAR ------------------------------------------------------------ ---------------------------------------------------------CCN AAYGARGCNTCNACNTTYATGTCNTGYGGNGAYGAYGGNACNGTNMGNTTYTTYGAYYTN MGNGTNAARACNAGYTGYACNAARCARAAYTGYYTNGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARAAYTCNGARGARYTN AARMGNGTNGCNAGYTTYATGTCNAAYGCNATHAARTCNGAYTCNGGNAARGTNTAYTTY GTNGGNACNGCNTGGGAYYTNYTNAARTAYGCNGCNAGYGGNTCNTCNCARGAYTGGGCN ATHCAYGCNAARCCNGAYATHTAYTCNTAYACNTAYGARYTNMGNCCNGAYTCNATGGAY GARMGNGGNTTYAAYYTNCCNCCNGARGARATHATHCCNACNGGNCARGARTTYTTYCAR AGYYTNGCNGCNTTYGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGNCARATGTGYTAYTCNTGYCARTAYGTNCARAAYGGNCCNGGNATH AAYTGYGTNACNGCNCCNYTNAAYTGGACNGGNGGNGARCCNMGNATHAARTGYCCNAAY MGNTGYACNATHGTNGCNGARTTYGAYGCNGCNACNGGNAARCCNACNTTYTTYCAYMGN GGNTGYGCNGTNGCNACNAARGCNCARAARGAYGGNTGYCARAGYAAYGGNGCNMGNGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GCNGTNATHGTNATHACNATGGCNGTN TCNTTYGAYGGNATGAGYTAYGGNGGNTAYATGGTNAAYCCNGTNGAYTTYGCNCCNMGN TAYGCNGGNGTNGCNTTYGGNATHACNGCNTCNGTNTCNATGATHTCNGGNATGYTNGCN CCNATHGTNGCNGGNGCNYTNACNCARAAYAAYACNCARGARGARTGGMGNAAYGTNTTY TAYYTNTGYGGNGGNYTNTCNATHTTYGGNGCNATHGTNTTYGGNYTNTTYGCNGARGGN GARATHCARTCNTGGGCN---------------------MGNAARAAYTTYYTNMGNGTN AARCARAAYATHGAYCARAAYYTNGGNMGNTCNGARAARTCNGARGTNYTNTCNGARGAY CARCARGARAAYGARAARMGNGTNGAYGTNGTNAARCAYGCNTTYCARAAYATHTGYAAR MGNACNAGYGCNATHYTNCARGCNCARGGNAGYGAYTTYGARAARMGNGTNAARAARYTN CCNGARAGYGCNYTNGGNCAYGCNYTNYTNGARTCNGCNCARTCNYTNCAYACNGARTCN YTNYTNGGNCARGCNTGYATGATGYTNGGNGAYTGYCARGGNAAYYTNGCNAARGARCAR GTNAAYCAYGARACNATGATHGARCARGARTTYATHAARCCNYTNACNCAYATHGTNGAR ATHGAYATHCCNAGYATHACNAARCAYMGNAARATHYTNAAYAARTCNATHYTNGAYATG GAYTCNGCNAARTCNMGNTTYAGYCARGCNATHMGNCARTCNACNGTNCCNGGNGCNAAY ATGTCNAAYGCNGCNAAYAARGTNGAYGTNATHMGNGARGARGTNGAYGARGCNACNAAY AARGTNGARACNAAYAARGAYAAYYTNTCNATHGARYTNTGYCARTTYACNGCNAARGAR AGYGARCAYGCNTAYGTNYTNYTNAARYTNYTNGARTCNCAR------------------ ------------------------------------------------------------ ---------------------------------------TCNCCNYTNCCNGAYCAYGAY TTYTTYTAYTAYGTNAARGCNGAYATGAGYYTNGGNCARAAYGCNTTYTGYMGNGCNTAY GTNAAYTTYYTNAGYGCNGARGAYATHTTYATHTTYMGNGAYAARTTYGAYGGNTAYGTN TTYYTNGAYGARAARGGNGGNGARTAYCCNGCNGTNGTNGARTTYGCNCCNTTYCAYAAR GTNCCNAARMGNAARGTNAARAARATGGAYTCNAARTGYGGNATHATHGARCARGAYGCN GAYTAYAARAARTTYYTNGARYTNYTNACNAAYCCNCCNGARGCNYTNCCNGTNTCNYTN GAYGCNATHGTNGARGARGTNGARGCNAARGARCARMGNYTNGCNAARATGAGYACNACN AARACNAGYACNCCNYTNYTNGAYTAYYTNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CAYTGYTTYTTYTCNGGNTAYTGY GTNGGNTAYTTYAAYCAYMGNTAYTTYYTNGCNATGTGYATHCAYATGACNTTYGCNGCN TTYTAYTGYAAYTTYTAYAAYTGGCARTAYTTYATHGAYCARAARGGNGGNTTYACNTGG ACNATHATHCCNGGNYTNATHGCNCCNCAYGTNGGNGTNATGYTNGGNTAYTAYTCNATH TAYGAR---GARACNATHMGNGGNGGNGGNGARYTNTTYAARTTYCCNTGGACNAGYTAY TCNAARGTNCARCARTTYCCNTTYAARTTYTAYTGGAARCAYGGNMGNYTNTTYMGNTAY YTNTTYTAYTCNTCNGCNYTNGTNTTYCCNYTNATGGTNAARYTNACNAARGCNACNTCN CCNTCNCCNCCNCARAGYTCNYTNCCNGGNCARGCNCARYTNCARYTNGGNGGNGTNCCN GTNTTYYTNCCNCCN---------------GGNYTNACNGCNGCNGAYCARATHCCNACN YTNGTNCCNGTNAGYGGNACNGCNCARATHGGNGAYGAYCARCAYMGNTTYYTNGCNCAR CCNYTNGGNYTNTCNATG------CCNMGNCCNGCNCARCCNTTYATHYTNGCNGCNCCN MGNYTNCCNCCNCCNACNGTNGTNGCNTCNACNCARGCNAAYATGAAYGGNACNGCNCCN CCNCCNYTNGTNTCNCCNCCNCAYGARGCNGCNGGNYTNGTNTAYAAYCCNTAYGCN--- ---GCNATGGGNAAYATGAGYTCNACNYTNACNTCNCCNGTNGAYCCNTAYGGNYTNGGN GCNGCNACNCCNCARGCNGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGNAAYTTYACNAARCAYAGYGGNGTNGARMGNGTN TGYGARGAYYTNAARAAYAAYCCNMGNCAYGGNAARTAYATHMGNYTNATHTCNCCNGTN CARYTNCARMGNYTNYTNACNATHGTNAARGAYAARATHAGYGGNYTNAGYYTNGARGCN AGYATHGCNMGNAAYAAYCARATGGARGCNYTNGAYCCNGARGARAAYYTNAAY------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------- >stearnsi YTNGTNATHGCNCCNYTNYTNYTNGGNGTNGCNYTNGCNGGNTAYGAYCCNTAYACNGAY YTNGCNCARYTNTAYMGNATGCARYTNYTNGCNGAYGCNTTYGGNGAYTAYATHCCNGAR AAYYTNCCNATHGAYAAYAAYGAYATHGAR------ATHMGNTCNTAYTGGCCNGARTTY ---------------GCNGCNTCNYTNGAYCCNACNAARGCNTCNGAYGAYATGTAYGGN TCNCARATGTAYAGYGGNGCNCAYATHMGNGAYCARGARCAYATHGARCAYAGYGCNYTN CAYGGNTAYCARTCNGTNGCNGGNGGNACNGCNGARGGNCCNGCNAAYAAYAARATGCAR AARAGYGAYAARCCNYTNCCNGCNTAYTGYAAYCCNCCNAAYCCNTGYCCNATHGGNAAR ACNGCNAARGAYAAYTGYGTNGARAAYTTYGARAAYTCNGCNGARAAYAAYAARAARYTN YTNAGYGARCARGAYTGYCCNTGYGAYACNGARCAYATGTTYAGYTGYCCNGCNGGNAAR GARACNGTNTCNTCNAARGGNAAYTCNGGNTAYCARCARACNYTNAAYAARGTNATHGAY CARYTNAGYAARATGGGNGCNGGNGAYGAY------GARAAYAGYGGNATHYTNAAYCCN ACNCARGARMGNTTYTCNACNGTNGCNAARAARTCNCCNCAYATHATHCAYAARMGNAAY GARCAR------GTNATGAAYCCNTAYTTYAARGGNACNACNAARGAYATHGCNGCNAAR AARAAYAGYAARYTNTCNCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GGNCARGCNTTYCCNCCNCARTAYAAYAAYGARCAYAARMGNTAYYTNGCNGCN AARGARMGNATGAARCARAAYCARAARAARAARGTNGCNAARYTNYTNCARGARTGGGAR AARGCNMGNGGNCAYGTNAAYGARGTNMGNAARACNGAYGCNAARACNGCNGAYMGNATG AAYGCNGARATHGCNGARMGNTTYAARCAYYTNTAYGCNTCNTTYAARCARGARGAYGCN TCNGARAAYATGCARYTNGCNGCNYTNCAYCARCARMGNGTNCARGCNTAYYTNAAYGAR AARAARMGNGARGCNATGGAYMGNTAYATGAAYGCNYTNGARAAYGGNAAYATHCCNATG GTNAARAARTAYYTNCAYAGYTAYATHAARGCNGARGARAARGAYMGNATGCAYACNGTN AAYCAYTTYAARCAYATHMGNAAYTCNAAYCCNAARGARGCNYTNMGNGTNCAYMGNCAY ATHATHAAYCAYYTNAARYTNTCNGARATGMGNATHGAYCARGCNYTNGARATGYTNACN CAYTAYCCNATGGTNGARMGNGARGTNMGNCCNGARATGGARGARTTYYTNAARMGNTTY AAYGARATHGCNACNAGYATHAARAAYGTNGTNYTNCCNGTNCCNGARGTNAAYAGYCAR GARGARACNAGYGCNAGYAGYGAYTCNGAYAGYTTYACNGCNTCNAAYGAYATHAGY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARGAYAARYTNTAYAARCARATHACNGTNGARGTNAARGGNCAYGAYCCNGCNGTN YTNAAYAGYTAYCARAARTTYACNACNACNGCNGCNGARCARYTNGGNGTNAARATHGCN AGYATHACNGARCCNCCNMGNGTNATHACNMGNAARAGYYTNYTNAARTCNGTNTTYATH TTYAARAARCAYATGCAYCARTAYGARGCNMGNACNYTNTTYMGNGTNTTYGARTTYAAR CAYYTNACNGARTCNACNGCNYTNACNTTYYTNGARTAYATHCARMGNAAYYTNCCNGAR GGNATGGCNATGAARGTNACNAARCAYGARYTNAARCCNATHCCNGAYCAYYTNAARCCN CCNAARAARTCNGARTCNGCNGCN------------GAYTAYTTYAAYGTNATGYTNGGN AGYCARYTNYTNTAYAARTTYGARMGNCCNCARTAYGGNGARATHYTNGCNGARCAYAAR GAYAARCCNATGTCNAGYATHTAYGGNGCNACNCAYYTNYTNMGNYTNTTYGTNMGNYTN GGNGCNATGYTNGCNTTYACNTCNYTNGAYGARMGNACNGTNCAYATHYTNYTNAAYCAY GTNCAYGAYTTYYTNAARTAYATGTCNAARAAYGGNTCNACNYTNTTYAARACNTCNAAY TAYGARATHGCNACNCCNGAYTAYCAYMGNAARGCNATH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TCNAARCARMGNTGGATHCCNYTNGAR TCNAAYCCNACNATHYTNAAYAARTAYGTNCAYGGNYTNGGNATGGAYAARGCNTGGAAY TTYGTNGAYGTNTTYGGNYTNGAYCCNGARYTNYTNGCNATGGTNCCNMGNCCNGTNGCN GCNATHGTNYTNYTNTTYCCNGAYGCNAARTCN------------CARAAYGCNATHGGN GARTAYYTNAARGARTCNCCNGARGAYYTNTAYTAYACNAARCARACNATHGGNAAYGCN TGYGGNACNGTNGCNYTNGTNCAYGCNYTNGCNAAYAAYCARGAYAARATHACNTTYGAR GARAAYAARGCNTTYTCNAAYTTYYTNAARGCNACNAARGCNATGAAYCCNGARGAYAAR GCNAARCAYYTNGARCARGAYATGGARATGGGNGCNGCNCAYGARGAYTGYGCNCARGAR GGNGAYACNGCNGTNCCNGCNGCNTCNGAYAARGTNAARTGYCAYTTYATHGCNYTNGTN CAYTTYAAYGGNACNYTNGTNGARYTNGAYGGNMGNAARGAYGGNCCNGTNACNCAYGGN CCNACNTCNGCNGAYAGYYTNYTNGARGAYGCNGCNGTNGTNGTNAARAARTTYATHGAR AAYAGYCCNTAYAAYGCNGCNMGNAGYGARATGYTNCARAARGAYMGNAGYACNCARYTN GGNAGYAARYTNACNYTNACNGGNAARGARATHACNGTNTCNGCNGCNATGGTNAARGAR AARGCNAARYTNATGGARGARAGYMGNYTNGGNGGNGCNGAYTAYTTYCCNTCNYTNAGY TTYTAYAARTCNAARCCNYTNATGGARGCNACNCCNYTNTTYAARYTNATHMGNAARATG CCNAARGGNGCNGCNYTNCAYYTNCAYGAYCARGCNATHACNAGYATHGAYTGGYTNGTN AARAAYGCNACNTAYMGNGAYAAYYTNTAYATGTGYGTNAAYACNGGNACNCAYYTNATG CARTTYCARTTYCAYAARGARGCNCCNAARGCNGCNTGYACNTGGACNTCNGTNMGNACN GARMGNAAYGCNGCNGCNAGYGTNTCNGARTTYGAYGARAAYATHAARMGNAAYYTNAGY ATGYTNACNACNGAYCCNYTNGTNACNTAYCCNACNGTNACNAARGCNTGGGARMGNTTY ATGCARTAYTTYGGNCARGTNTTYAARATHATHTTYTTYGARCCNGTNTTYMGNGAYTAY AAYATHCARGCNYTNACNGARTTYTAYGARGAYAAYGTNCARTAYATHGARYTNMGNTCN YTNTTYGAYGGNATHTAYGAYATHAAYGGNAARGTNTAYGGNAARGARAARGCNTTYGAR ATHTAYMGNGARGTNGCNGARGARTTYAARAARAGYCAYCCNGAYTTYATHGGNGCNAAR TTYATHATGTCNGGNATHMGNGCNAGYCCNAAYGGNGTNATHYTNGARCARATHAARGAR ACNATGGCNATGMGNAARGARCAYCCNGAYTCNATGYTNGGNTAYGAYYTNGTNGGNCAR GARGAYCCNAAYAARTCNYTNYTNTAYTAYMGNGAYCARYTNYTNTAYCCNGGNCARGTN GARCCNAAYAAYCCNYTNCCNTAYTTYTTYCAYGCNGCNGARACNAAYTGGCARGGNACN GARACNGAYTAYAAYYTNYTNGAYGCNYTNYTNYTNAAYACNACNMGNATHGGNCAYGGN TTYGGNYTNATHAARCAYCCNAGYYTNATGGAYYTNGTNAARGARMGNGARATHGGNATH GARGTNAAYCCNATHTCNAAYCARATHYTNGGNYTNGTNAARGAYYTNMGNAAYCAYGCN ATGACNCCNYTNYTNGCNGAYAGYTTYCCNATHGTNATHAGYTCNGAYGAYCCNGCNGTN TGGGARGCNGCNCCNYTNTCNAAYGAYTTYTAYYTNACNTTYATGAAYATGTGYGGNGAR GAYGCNGAYYTNMGNTTYYTNAARCARYTNGCNATHAAYTCNATHMGNTAYAGYGCNATG ACNGAYGCNGARAARACNGTNGCNATGACNAARTGGCARGCNAARTGGAAYAARTTYATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYTCNTAYGGNCAYTCNMGNTAYMGNMGNTCN ACNCCNTCNGAYAAYATGYTNGTNACNCCNCCNCCNATGGAYGTNAAYGGNGAYGAYATH GTNGAYGAYAGYCARGGNAAYYTNAARATGGAYGAYGAYGGNGAYGAYGCNTAY------ ------YTNYTNTAYCCNGAYTTYGCNGAYGTNGTNGTNGAYGARAAYGGNAARGTNTGG GAYGGNAARACNGGNGARGARYTNAAYAARMGNGGNTAYAAYGGNYTNAAYATGYTNMGN YTNGGNAARMGN---------------------------------CARMGNGARAGYYTN AAYTCNGARTTYACNGAYAGYAAYGAYAARMGNTCNTTYAAYATHYTNMGNYTNGGNAAR MGNAAYYTNAAYATGYTNMGNYTNGGNAARMGNYTNCCNGGNGCNGAYGARGAYCARAAR MGNAAYYTNAAYATGYTNMGNYTNGGNAAR---------------------------AAR MGNAAYYTNAAYATGYTNMGNYTNGGNAARMGNCARYTNAAYATGYTNMGNYTNGGNAAR MGNCARYTNAAYATGYTNMGNYTNGGNAARMGNCARYTNAAYATGYTNMGNYTNGGNAAR MGNGAYGTNGTNGGNGAYGARGCNGCNAARMGNAAYYTNCARATGYTNMGNYTNGGNAAR MGNCARGAYGAYGAYGCNGARAARMGNAAYYTNCARATGYTNMGNYTNGGNAARMGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGARAAYCARCARAGYATHTTYYTNGTNYTNTTYGGNTCNYTNATHTGYGCNAGYYTN GTNACNTGYYTNCCNAARMGNTCNGCNGAYGAYATHYTNCARGAYACNTCNGGNATGGTN YTNGAYAARMGNCCNAARTAYATGGAYACNMGNMGNGAYYTNGAYGTNTTYAARGAYYTN GTNYTNATGAGYGTNCARGARYTNGTNGAYGARGGNMGNYTNGARTCNTCNGTNYTNCCN GARGAR------GAYMGNGARACNAGYAARCCNGTNGARAARMGNMGNTAYATGGGNYTN TGYATGCAYMGNCARGCNAAYCARTAYATHCCNTTYCCNTGYYTNMGNACNGGNMGNATG AARTCNGCNYTNTGYYTNYTNYTNATHGGNTGYGCNGCNGTNYTNGCNGAYAAYTAYYTN TGY---CCNAARGAYGGNGAYTAYTTYGARTGYTAYGARTCNGAYGCNGAYTAYMGNGCN TGYYTNACNAAYGGNMGNMGNGGNGAYTCNTAYGTNGTNTGYTCNAARTGYAARMGNAAR TGGGARTAYTGYGTNACNAGYGGNAARTTYGCNGARTCNAARCAYCCNGARTCNGAYTGY GGNGCNGAYTAYGARAGYACNCCNTGYACNCCNAGYAAYTCN------------------ YTNATHATGYTNYTNCARTGYTTYACNACNMGNGCNTTYCCNGGNTAYMGNGGNGTNATH CCNAAYGGNTAYMGNGTNCCNGARCCNTGYAAYCCNGAYAARATHTGGCAYGGNGTNGGN CAYYTNAAYCCNGGNGGNGGNGGNGARMGNAAYCCNTTYGGNAARGAYTTYGCNGCNGCN AAYCAYGARTGGACNAARGAYYTNTGYGARAARGAYTCNGAYGGNGAYGGNYTNACNAAY GGNCARGARYTNGGNGAYCCNAAYTGYATHTGGACNCCNGGNCARCCNGARACNTCNACN ACNGGNYTNTCNCAYCCNGGNATHAAYGAYACNGAYTGYGARTGYGTNAGYACNATHATG TCNAARCCNTTYGTNAARGARTAYAAYAARGTNMGNTAYGARGGNTTYYTNAARGAYGTN YTNGAYAARATHGCNGARAARGCNAAYTTYAAYTAYACNTTYACNGARCCNGARAARYTN GTNTAYGGNGCNGAYTCNCCNTAYGGNTGGAAYGGNGTNATGGGNGAYGTNAARGAYAAR AARGCNGAYATHGGNGCNCCNYTNACNGTNACNAARGARMGNGARATGGCNGTNGAYTTY ACNAARCCNTTYYTNTCNGAYGGNGTNAAYYTNYTNGTNAARAARCCNACNTGGTTYGAY YTNGGNYTNGGNTAYYTNGTNMGNCCNYTNTCNTCNGAYTTYTGGATHATGYTNYTNGTN GTNYTNYTNYTNATHGGNYTNGTNTTYTTYATHATHGGNAARTTYAGYCCNTAYGARTGG GGNAAYGTNGCNGCNGAYAARGAYCCNMGNGGNGCNAARAAYAGYTTYACNYTNMGNAAY AGYTAYYTNTTYGCNYTNACNACNYTNTCNTGGCARGGNTTYMGNGARGCNCCNAARTCN YTNTCNGGNMGNATHATGGCNGCNTTYTGGYTNYTNTTYGTNYTNTTYACNYTNATHGCN TAYTCNGCNAAYYTNACNGCNTTYTTYMGNCCNGARCARATHCCNAARYTNCCNTTYAAR ACNTAYGAYGARYTNYTNATGTCNGAYATHACNCCNATGACNAAYGAYTTYAGYTCNACN GCNACNTTYYTNMGNACNAGYCAYAGYAARACNYTNMGNGAYYTNTGGAGYAARATGGAY AAYACNGGNGCNYTNYTNAGYTCNGAYGARGARGGNGTNGAYAARGTNMGNTCNAARGGN AARGAYTAYGCNYTNTTYATGGARACNMGNATGGCNCARTAYCAYGCNATGCAYGARGAY TGYAARYTNYTNGTNTAYGGNGARACNYTNTTYCAYAGYACNYTNGCNTTYGCNGTNCAR AARGGNTCNGCNYTNAARCARATHATHAGYGAYGARGTNGARGARYTNMGNAGYAAYGGN ATHYTNGARGARYTNACNAAYAARTAYTGGAARTTYGGNGGNMGNTGYACNYTNATHATH ATHTCNTCNTAYACNGCNAAYYTNGCNGCNTTYYTNACNATHGARAARYTNGTNGCNCCN ATHAAYTCNGCNGAYGAYYTNGTNGAYCAYCCNAGYATHAARTAYGGNACNAARAARACN GGNACNTCNTGGMGNTTYTTYCARCAYTCNACNATHGAYACNTAYATHCARATGMGNAAR GCNATGGARGARAAYGARGAYGARGTNYTNTTYACNAAYTAYGAYGAYGGNGTNMGNAAR GTNMGNGARTCNAARGGNGAYTAYGCNTTYYTNYTNGARTCNGCNATGAAYTCNTAYCAY GCNCARCARGARCCNTGYGAYACNATGATGGTNGGNGAYCCNYTNGAYAAYAARGGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNTTYACNYTNTGYYTNTTYGCNGGNAGYACNTAYGCNGTN TTYTAYATHCCNGGNTCNGTNGTNAGYTAYCCNAARATGGGNAARMGNGCNTTYTAYACN AAYGCNACNGGNAAYMGNTAYCCNYTNATHGGNMGNMGNTCNTCNTCNTCNTCNTCNACN AGYTCNGARGGNCARGGNCARGGNGARGGNCARGGNCARAAYGCNGARGTNGCNGTNGCN GGNGCNATGAARMGNGGNGTNTTYACNCARGGNCCNCAYMGNAGYYTNCCNMGNGTNGGN MGNTCNGGNGTNTCNGAYGARAAYTCNGARGCNACNGTNAGYGGNAARATHMGNAGYGAR ATHYTNAARGGNYTNGCNGARMGNYTNGARGGNAGYGAYTTYAGYACNYTNYTNACNGGN CARCARMGNGCNYTNTCNGGNGARAGYACNGAYTCNYTNCCNCARTTYYTNTTYYTNATH TTYGAYGARGAYGGNGAYAAYCARYTNAGYAARGTNGARTTYACNTCNGGNYTNGCNAAR GTNYTNGAYCARAAYYTNYTNTGYMGNACNAGYGTNATHCCNCARACNTCNYTNGAYACN CCNGTNAARYTNTCNGTNGGNATGACNYTNATHAAYATHCAYAARGTNGAYACNGARACN MGNAGYGTNTAYYTNGAYGCNTGGGTNAAYATGGGNTGGAAYAGYAGYATHACNTTYGAY CCNAGYATGTTYCAYAAYYTNACNTTYACNMGNYTNCAYACNTCNAARATGTGGYTNCCN GAYATGGCNGTNTAYAAYGGNGARACNYTNGTNGAYAAYGARYTNGCNMGNCARGTNATG CARTTYTCN---TCNGGNGAYGCNTTYTGGGTNCCNAARACNAARATHMGNGTNGTNTGY AAYGTNACNGAYGCNTCNYTNGCNGCNAAYACNACNTGYAGYGTNAARATGGGNTCNTGG ACNTAYGGNAGYTCNCAYATHTCNYTNGAYAGYAAYCCN---CAYATGGAYGTNTCNAAY TTYGAYGCNAAYTCNMGNTAYGARATHGTNGCNCAYTCNGCNGTNAARGARTCNAARAAR TAYTCNTGYTGYGARGARYTNTTYGARAAYATHYTNTTYAAYTTYACNTTYMGNAARMGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------YTNYTNTCNYTNGCN ATHGTNTTYATHTCNCARGCNCCNTCNACNCARGCNAAYYTNGARCAYGTNTGYAAYCCN GAYTCNTTYGCNAGYCARGGNMGNGGNYTNTGYGGNGCNAAYYTNGTNTCNCARYTNCAY TTYGTNTGYTCNCAYTTYAAYGGN------CCNYTNYTNGAYAARTAYGTNGTNAARMGN AGYTAYCCNACNGARATHGAYMGNGARGTNCAYGAYYTNYTNATHAAYAARAARGAYGCN TTYTCNTTYYTNTCNAARMGNCARAGYAGYCARAAYATHGTNTGYGARTGYTGYGTNAAY TCNTGYAAYTTYATHGARYTNYTNCARTAYTGYGARYTNCCNAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR MGNGGNGCNCCNMGNTTYATHGGNAARMGNGGNGCNCCNMGNTTYATHGGNAARMGNGGN CCNCCNMGNTTYGTNGGNAARMGNGGNCCNCCNMGNTTYGTNGGNAARMGNGGNCCNCCN MGNTTYGTNGGNAARMGNGARYTNGARYTNCARYTNGARATHYTNAAYGAYATH------ ------------------------------TAYGAYACNAARMGNGCNGTNCCNMGNTTY GTNGGNAARAARAGYAARAGYMGNYTNCARGARAAYGAYGTNCARTCNTTYYTNGAYAAY TGGAGYMGNCARGARGCNATHAARAARYTN---------GTNGAYAAYGAYAARMGNTGG GCNAAYCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TAYGCN YTNGAYGCNGCNGTNACNATHATHGARAARTAYAAYAARTTYTTYGGNATHGCNTAYCCN YTNGARAARCARGAYYTNATHGCNATHCCNAAYTTYGCNGCNGGNGCNATGGARAAYTGG GGNYTNATHACNTAYMGNGAYACNACNGTNYTNCAYGAYCCNGARAARTCNACNGCNTTY TCNAARAARGTNGTNGCNYTNGTNGTNGCNCAYGARYTNGCNCAYCARTGGTTYGGNAAY YTNGTNACNATGAARTGGTGGAAYGAYYTNTGGYTNAAYGARGGNTTYGCNTCNTAYGTN GARAAYATHGGNGCNCARACNGTNGAYGCNAGYTTYCAYATGTTYGAR---TCNATGGTN TCNGARGGNMGNAGYACNYTNAAYYTNGAYAGYYTNAGYTCNTCNCAYCCNATHGARGTN CARGTNGARGAYCCNGCNGARGTNGARTCNGCNTTYAAYACNATHACNTAYAARAARGGN GCNTGYYTNATHCAYATGYTNAARGGNGCNATHGGNGARGARGARTTYCAYCARGGNYTN AAYTTYTAYYTNMGNGTNCAYGCNTAYGGNAAYGCNGARACNAARCARYTNTGGGARGCN TTYGARAARTAYAGYAAYGAYAAYYTNMGNGTNTCNGARTTYATGGAYACNTGGACNAAR CARATGGGNTAYCCNGTNGTNATGGTNACNMGNCARGARGGNYTNATHAARYTNACNCAR GARMGNTAYYTNYTNAAYAAY---------------GAYTCNGAYACNTCN------TCN TAYTCNTGGCAYATHCCNTTYAARTAYAARYTNTCNGAYAAYYTNAGYGARACNAARATG GTNTGGATHAARAARGGNGAYGARGTNATHCCNYTNCCNTCNTCNTCNACNTGGATHAAR GGNAAYGCNAAYAGYGARGGNTAYTAYMGNGTNAAYTAYGAYAGYGCNGGNTGGAARGCN ATHGCNCARCARYTNATGAARGAYCAYACNGTNTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGACNACNMGNGGNACNTCNAGYATHTCN CCNCCNGTNCARATHCCNCARCCNMGNCAYGTNTCNACNATHTCNTCNGGNACNCCNCCN CCNAAYCARCARYTNTTYCCNGGNCARTCNCCNGGNYTNGTNCARGGNCCNACNTAYAAY TTYATHCARCCNCARTAYCARCARAGYGARCARTTYYTNTCNTAYCARGCNTAYGGNAGY GCNCCNAAYGAYYTNMGNGGNGCNACNTCNACNAGYGGNMGNGGNGGNGCNGGNCCNGCN AAYATGGCNCARTCNGGNACNTAYTAYCAYCARACNAAYCARAAYATGMGNCCNTCNCAR CCNCCNCCNCCNAAYCAYTCNCARCCNTAYTTYATHAGYCARACNGGNCARAGYAAYATG MGNCAYCCNMGNCCNATGGTNTTYATHCARCCNAAY---------------CCNCCNAAY AAYATGGTNATHCCNGCNAAYATGTAYCARCARACNGCNMGNATGCCNYTNTAYGCNCAR GGNGGNCCNCARTAYCARGCNMGNTTYACNCARCCNAGYGGNATGATGTAYTTYAAYGGN ACNTCNGTNCCNATGCARGCNCCNGGNATGGGNCCNCCNCCNGCNCCNMGNGARAARMGN TTYATHAAYATHAGYGAYCCNAAYACNGGNMGNAAYATHACNAAYGARATHATHAAYTCN CARCARTCNACNGAYGARAARAGYGARCAYGARGAYTCNTCNGCNAAYGAYAARGGNGTN GARATHMGNAARAAYTTYACNMGNCARGTNGTNGARMGNATGAARATHGCNGARGGNTCN GCNTCNCCNAAYCAR------CARTCNACNGARCCNGTNAAYCCNGCNTCNCARTCNGGN AGYYTNTCNCARCARAAYCARCCNAGYCARGARCAYCCNCARATGCCNACNTCNTTYCCN CCNGGNCAYCARCARCCN---CARTCNACNCCNCCNYTNTCNGGNGCNGCNCCNGGNCCN GGNTCNATHATGMGNCCNCCNGGNAGYCCNGCNATHAAYYTNAGYGTNCCNCCNCCNCAR YTNCCN---------CCNAAYATGGTNTAYAAYAGYMGNCAYGGNCCNAGYCARCARACN ATGCCNGGNCCNGCNCCNGTNCARACNCARCAYGTNYTNTCNTCNAARGGNCCNCAYCCN CCNACNGARGTNGCNGCNCCNACNYTNACNMGNCARTCNCCNCCNGCNCCNGARTCNGCN CCNYTNAARGTNGTNCCNCCN---------ACNGTNCCNYTNACNCCNGTNGAYACNAAR CARYTNAARGCNGAYTCNCARACNGARTCNGCNGTNACNAARGAYCAYGTNGCNGCNGGN AARCARCCNGTNGARTCNATGAARAARGARATHGAYGCNGTNGCNAGYYTNGGNAARGAR GAYAGYGGNAGYGGNGCNAGYACNCARGGNAAYAARGAYGGNMGNAARGGNAARAARAAY AARAARGAYTTYAAYMGNAARGARAGYGGNGGNTCNGAYATGGAYGCNTTYATHGAYGAY AGYAAYGTNACNAAYAAYGGNAGYGCNMGNYTNGCNGAYACNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNAARNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN NNNAARGAYAGYGGNGTNNNNNNNGANCCNNNNNNNNNNNNNNNNNNNNNNNNNACNTCN YTNNNNGARAGYAARCCNCARGAYAARGTNCCNACNCCNCCNCCNGCNGARCCNYTNGAR GTNAARAARGARAARGARCCNTCNTCNCCNGTNGAYTCNTCNYTNGARAARCCNGCNAAR TCNGTNGARACNAGYCCNGARAARGARCCNGCNGTNCCNAAYGTNGAYGCNGTNAARGTN CARAAYGGNAGYCCNTCNGTNGTNAAYTCNGTNCCNGARGARATGCCNGCNGAYAARGCN GAY---GAYCARATHAAYAAYGARCAYTAYCCNGARGARAAYGGNACNYTNAARATHGAR GAYGTNGARCCNTCNAAR---GARGTNTAYGCNAARYTNAARAAR---AGYGGNGGNAAR YTNGTNTAYGAYMGNGCNTAYYTNATGGARYTNMGNGAYTGYGCNTCNTCNCARGCNAAR CCNGAYGGNYTNCCNGCNYTNGARATHATHYTNGAYCARCCNAGYCCNTAYATGTCNMGN TCNTCNATG---GGNCCNGCNGAYTTYACNCCNGCNTTYTTYCARACNGGNGTN---AAY CARMGNCAYGCNCCNCCNATHGGNAARAGYAGYAGYMGNGGNMGNCARMGNCCNGGNGAY ATGCCNGGNACNCCNMGNGTNATHAARAGYATHTCNATGTCNAAYGARACNAAR---YTN CAYCARAGYGARAAYCCNTGGAARYTNACNAAR---------AARGARGAYAARGAYGAR CARAARAGYYTNGARGGNGARATHYTNTTYATHATGAAYMGNYTNACNCCNACNAAYTTY GARAARYTNGCNATHGARATGAARAAYYTNAAYGTNAARACNTAYGARGAYYTNCARTAY ATGGTNAARACNTTYTTYGAYAARGTNACNYTNGARACNAARTTYGTNGARGCNTAYGCN CARYTNTGYAARGTNATGTCNGGNYTNMGNGTNCCNCCNCCNACNGAYGGNAGYGTNAAR GARAGYATGGCNACNTTYMGNGTNGTNATGYTNACNAARTGYCARCARGARTTYGARGCN GAYAARTCNATHATHTTYGARGAYCCNGARGARAARAARMGNAARYTNGARGCNGARAAY CCNGGNAARACNCCNGARMGNGARGARYTNATHGARAARACNYTNTAYCARATGAARYTN AARMGNATGAARTTYTAYGGNAAYATHMGNTTYATHGGNGARYTNTTYAARYTNGGNATG YTNACNGARAGYATHATGCAYGAYTGYATHTAYMGNYTNYTNAARGCNMGNGAYGAYGAY TCNYTNGTNTCNYTNTGYAAYYTNYTNACNACNGTNGGNTCNAAYYTNGAYACNGARAAR GCNAARCCNMGNATGGAYCARTAYTTYYTNAARATGACNAAYATHGCNGAYGARMGNAAR TCNMGNATHAARTTYACNYTNMGNGAYGTNATHGARYTNMGNCARAAYCAYTGGGTNCCN MGNAARCARGCNACNGGNCCNAARAARATHGAYGARGTNCAYAARGAYTTYGCNGARGAR CARATGMGNAAYCARTAYYTNGCNTCNCARGCNYTNYTNCCNMGNGTNGAYAAYTCNCAR GCNGGNAGYMGNMGNGGNAGYMGNCARMGNCCNGAYGARAAYAARATGGGNGARGAYGGN TGGAAYACNGTNGGNAAYCCNAARTCNTTYMGN---ATHGAYGCNTCNAARATGAARATH TCNTCNAARAGYGTNGTNGAYGAYAAYATHCARYTNGGNCCNGGNGGNGGNGCNCAYAAR CARCCNATHTGGAGYMGNGGNAGYCAYGGNGGNACNCARCARCCNCCNTCNGAYGAYMGN CCNGCN---YTNGGNAAYMGNTTYTCNGCNYTNACNAGYGAYGAYGCNMGNMGNTCNTTY CCNMGNTCNCCNTCNMGNGGNGARGGNTCNGCNGGNMGNGGNYTNMGNCARGGNCARACN GCNGGNCAYGGNMGNGGNAARATHATGTCNMGNTCNAGYCARGARGGNGARMGNMGNGAY GCNATHGCNAAYACNMGNTCNTTYATGAGYGGNMGNTCNCARAAYTCNAGYMGNGAYAAY AGYTGGAAYMGNGAYGAYMGNMGNCARYTNATGGGNCCNMGNAGYTCNTGGGAYMGNGAY AAYCCNATGACNMGNAGYGAYAGYGCNGTNMGN---ACNGARGARTTYAARACNCCNGCN CCNCCN------GCNGTNAARCARATGTCNGARTCNGARATHGARACNAARGCNGTNAAY ATHYTNGAYGARTAYYTNAAYATHMGNGAYATHGCNGARGCNAARYTNTGYATGAARGAR YTNATHGGNCARAAYCAYYTNCAYYTNGTNGTNACNGCNAGYATHAAYAGYGTNYTNGAR AARMGNGAYGAYGAYMGNCAYATGGCNGGNAAYYTNTTYAAYGARYTNGTNAARAAYAAY ATHATHCCNGTNAAYTCNTAYACNAARGGNYTNAAYGARGTNYTNGARTTYGCNAGYGAY ATGGTNGTNGAYATHCCNACNYTNTGGAAYTGYYTNGCNGARGTNATHTCNCCNGTNYTN GAYGGNGGNTCNYTNCCNTGGTCNAARYTNAARCARGCNTTYACNCCNCAYYTNGAYAAY AARGAYGGNGCNAARYTNATGGCNGCNYTNYTNTCNCARTGYGTNGCNAARCARGGNGAR AARGTNGCNGCNCARGARTGGCARAAYAGYGGNYTNAGYTGGTCNACNTAYYTNAARCCN GAYGARYTNAAYTCNTTYGTNACNGAYAARAARYTNGGNTTY---ACNYTNGGNGTNTCN CCNGGNGGNGCNGCNACNYTNCCN------------------------------------ GAYYTNGARAARATGATHMGNAAYCARGCNTCNAAYAAYGAYYTNYTNTCNTAYATHGAR AARACNGTNCAYGGNAGYAARTCNGAYTCNAGYTTYATHMGNGCNYTNACNACNGCNGTN GTNAGYTCNTCNATHAAYGARAAYAARAGY---------ATHAAYGARGAYGTNATHAAR AAYAAYAARGAYYTNYTNCARMGNTAYYTNGGNAAYTCNGTN---GAYYTNCARYTNCAR GCNYTNTAYGCNATHCARACNYTNATGGTNAARYTNGARCAYCCNTCNGGNGTNYTNGCN AARYTNYTNGARYTNYTNTAYGAYGARATHTCNATGGARGARGARGCNTTYTAYAARTGG GARAARTGYGCNGAYGCNCARGARCARGARGGNAARGGNACNTGYYTNATGCARGTNMGN CAYTTYTTYATHTGGYTNMGNGARAAYGARGARCCNGAYGCNGARTCN------------ ------------------------------------------------------------ ---------------------------------------AGYTGGTTYGAYGAYYTNGAY CCNGAYYTNTCN---GGNGAYCCNYTNGGNGAYGAYAGYATGGARGCNTTYATHAAYYTN GAYAARTTYYTNAAYGGNAAYTCNTTYTTYGAYGAR------GARGGNAAYYTNACN--- GTNGARGARGCNGCNGARGTNGCNCCNGTNATHAAYTTYGARCCNGARACNACN------ ---------CARGARCCNACNGTNGARCCNGTNGAYTTYYTNACNGGNTCNGGNGGNAAR AARCCNTCNMGNAARMGNAARGCN---GGNTCNMGNGARGGNGTNAARACNAGYYTNTAY GARATHCCNACNACN---------------TCNGTNATHCCNGARATHATHCARTCNACN ACNYTNTCNGAYACNGARYTNGAYCAYGAYTAYAGYACNAARMGNCARMGNATGGCNGTN CCN------------------GARGGNAAYGAYAAYACNCCNTCNACNAGYGGNGCNATG MGNGARTGYACNCARCAYGGNATGGAYATHCCNGARATGGTNYTNGCNAAYGCNTCNTGY AGYCCNGTNCARYTNYTNGAYGARAGYYTNGAYAARCARACNATHMGNMGNATHAARAAY AAYCAYGCNTCNAARMGNTCNMGNGARCARMGNAARCARAARTAYGTNGARATGGAYGTN GARGCNGARGARYTNGTNGTNMGNAAYCARCARYTNMGNGARAARATHGTNGAYYTNGAR GTNYTNGCNAARGARATGAARGCNATGYTNGTNGCNAARATGGCNGGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGGCNGAYAAYGCNGTNGAYTCNACNAARAAYGARGARGAYGGNACNGAY TCNGCNGAYTCNAARGTNTCNTCNTCNTTY---------GGNGCNCAYGCNMGNTCNTAY TCNGAYTCNACNCCNTCNGCNCARGAYAGYAAYCARGARGTNAGY---AGYTCNGAYATH ACNGARTCNGGNTGYYTNTCNCAYCCNCCNAARGTNCCNGGNACNTCNATGAGYCCNTAY AGYAAYGCNTTYTAYGGNAAYACNCAYAAYTCNGGNATGTAYACNAAYCCNTTYGTNCCN MGNGCNCCNYTNAARTCNGAYGTNGTNTCNACNGAYCARTCNAAYAGYAGYGAYAGYMGN GARGGNYTNATHGCNCCNAGYMGNYTNAAYGCNGCNGTNAAYMGNGAYAGYTCNGARGTN GARGGNACNMGN------TCNTTYCCNAARCARTCNGTNYTNGCNCCNCCNAARYTNACN AGYGCNGTNTTYGGNGGNGGNGGNGCNAGYCAYGAYACNCCNAGYTCNACNTTYAAYTCN TTYAAYTCNTAY---ATHMGNCCNTCNGTNTTYTCNGGNCCNTTYGAYTCNCCNGGNGGN MGNGGNGCNGCNCCNYTNYTNAARCCNGCNAARYTNCCNGAYCCNACNAARTCNTGYGAY AGYAARGCNGAYTCNGCNAGYGARGCNGARGTNAAYGTN---------AAYGCNAARTCN GGNGARGCNTCNTCNGCNAGYGAYMGNYTNAGYGGNGGNGAYGGNGCNTCNGGNGGNAGY GARGTNTCNTCNTCNTCNGCNTCNTCNTCNGTNCCNCCNCCNGCNCCNCCN------ACN GAYGGNGARGGNGCNGTNGGNGGNGARAGYACNCCNTAYAAYCARGAYATHGTNCCNGAY ATHAAYAARAAYAAYMGNYTNAARGAYACNTCNGGNGTNTCNAGYAGYTCNCARTCNTTY GTNTTYGGNAGYAAYYTNTCNCARMGNGTNACNGGNATHYTNTCN---TCNCCNGTNGAR AAYGARGCNTCNGCNTCNGCNGGNTTYGTNTTYGGNGARTCNYTNGGNTCNMGNGCNGTN GTNGARACNAAYGGNTCNACNYTNCCNCAYAARGAYGAYGARAGYGAYTCNGAYTCNGGN GCNAARYTNAAYCARACNYTNGARGARTCNGCNMGNGARTAYCARGCNAARCAYGARAAY AARACNGARYTNAARGARGTNGARACNATHACNGGNGARGARGARGARTCNAAYGTNYTN CARGCNAAYGCNAARYTNTTYTTYTTYGARACNAGYAAYGARTCNTGGGTNGARMGNGGN MGNGGNACNATHMGNYTNAAYGAYATGTCNGCNMGNGAYAAYACNAAYTTYCARTCNMGN YTNGTNATGMGNACNCARGGNAGYYTNMGNGTNGTNYTNAAYGCNAARATHTGGCCNGGN ATGTCNGTNGARMGNGCNTCNACNMGNTCNATHMGNATHACNGCNATGGAYACNGAYGAR TCNATHAARATHTTYYTNATHACNACNAAYGTNAARGAYTCNGARAAYYTNYTNMGNGCN ATHGAYTGGMGNATHCARCARYTNAARATHCARGARGARCCNGTNMGNCARCAYTCNGAR TCNMGNATHGGNGAYAARMGNAARGCNGAYGAYTCNGAYTTYGARYTNCCNATHAARAAY AARAARGTNAAYAGYTCNCCNGAYCARGGNATHTCNATHACNAARAARGARGARTCNGAY AGYAGYGTNCARGAYCCNGARACNGARGCNTCNTGYGARAGYCAYTCNTCNTCNYTNACN ATHAARTCNGARTCNGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYGTNTCNYTNGGNCARATHTTYGTNTGYYTNTCNTCNYTN CARGCNYTNMGNGTNGTNYTNGAY---GGNCCNCAYAARACNYTNGTNGCNGCNGTNGCN GTNGCNTCNGGNATGTGGGTNCARTCNGTNYTNTCNGARGCNYTNAAYACNTGGYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGCNTCNTCN AAYGTNTCNMGNACNGTNGTNAARTCNYTNAARGGNMGNACNTTY---TCNGCNGCNGCN GCNCARGCNCARMGNGCNCAYAGY---GAYAGYGCNCCNAARTGYTCNGTNAARAARYTN AGYAAYGGNATGAARATHGGNGTNATHCAYTCNAAYTCNCCNATHTCNMGNYTNGCNGTN GTNGCNAAYGCNGGNTCNMGNTTYGARAAYGGNGAYAAYCARGGNGTNTCNCAYTTYYTN MGNATGTCNTCNMGNATGMGNACNGARAAYATGACNAGYYTNGGNATHACNMGNACNATH CARCARATGGGNGGNGAYATHACNATHATGGGNACNMGNGARTAYATHTAYTAYAARACN AAYGTNACNMGNAAYTGYGCNGARAARGCNGTNMGNATHYTNCARGARATGACNACNAAR CARGCNTAYATHGGNTGGGARATGGCNGAYGTNCARGGNGAYAARAAYGGNATGGCNYTN GAYYTNGCNYTNTAYCAYACNCARCCNCAYGTNMGNGCNGTNGARYTNYTNCAYTCNGCN GCNTTYMGNAAYACNYTNGGNAAYTCNYTNTTYGCNCCNGARCAYATGATHGGNAARTAY ACNCCNGARCARGTNATGCARTAYGTNAARACNCAYTTYAGYGGNGGNMGNATGGCNYTN GTNGGNATHGGNGTNGAYGARGCNGTNYTNGARGAYYTNGCNTCNGCNTTYGARCCNTAY GCNTCNGCNGGNGTNCCNGTNGARAARGCNGCNTAYTAYGGNGGNGGNGARATHMGNCAR AAYACNGGNGGNGAYGTNTCNTAYGTNGCNGTNGGNTGYGGNGGNCCNAGYYTNACNAGY AARGARYTNYTNGCNGCNGARGTNYTNMGNCAYATHYTNGGNATHGGNCCNCAYATHAAR TAYAGYAGYGGNACNGCNGGNGCNCARYTNGCNAARGCNGCNGCNGGNGCNACNGAYGCN CCNTTYCAYGTNTCNTGYYTNAAYGCNAAYTAYAGYGAYAAYGGNYTNTTYGGNTTYACN GCNGTNTCNCAYGCNTCNCARATHGARAARGTNYTNCARGCNGCNTGYACNCARYTNAAR GGNYTNYTNTCNGGNAARATHACNGAYCARGAYGTNAGYAARGCNAARAAYCARYTNAAR GCNGARATHTGYATGCARTTYGARAAYCCNGAYGTNYTNYTNAAYTGGYTNGGNGARCAR GCNYTNAAYAGYGAYCARATHGTNACNCCNGAYGAYATHTAYAARATGGTNGAYAAYGTN AAYACNAAYGARGTNAARACNGTNGCNAARAGYATHYTNAAYTCNMGNCCNTCNATGGCN GCNGTNGGNAAYATHGCNAAYGTNCCNTAYYTNGAYAARYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GARCCNTCN--------------------------------------- ------------------------------------------------------------ ------------------------------------GCNCCNGCNGARGARACNCCNGCN CCN------------------------------------------GARGTNGCNGARGCN CCNGCNGCNGARGARGCNCCNGTNGCN--------------------------------- ---------------GARGARGCNCCNGCNTCNGTNGCNGARGAR--------------- ------------------------------ACNCCNGCNCCNGCNGCNGARGAR------ ------------ACNCCNGCNGCNACNGARCARGTNCARACNCCNAARAARAARATHCCN AARYTNGCNCARACNGTNAAYAARGCNMGNGGNATHYTNCAYTTY------TCNAARGAY AARGARGGNTCNCARAGYYTNAAYGARGARAGYACNCCNGCNACNCCNACNGAYACNGCN GARACNGGNGCNGCN---------GAYGGNTCNGCNGCNGARACNGGNGARGTNGCNGCN ------AARGARTCNGCNCCNTCNACNGTNMGNACNGARTTYAARTGGGARAAYGGNGGN GAYACNGTNATGGTNAGYGGNACNTTYAAYAGYTGGCARGARAAYATHGCNYTNTCNAAR GARGGNGAYATHTTYACNGGNTTYATGGAYYTNCCNGTNGGNGARTAYYTNTGYAARTTY ATHGTNGAYGARCARTGGGTNGTNAAYAARAAYYTNCCNATHMGNTCNGGNGAYGAYGGN CARGARAAYAAYGTNATHYTNGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARACNATGGCNATGGAYGCNGGNGARYTNTTYGGNTTYTCN CARGTNTAYAAYCAYCAYAAYGGNYTNACNCCNCCNYTNYTNGARAARAARGCNGCNAAR YTNMGNGARATHTAYTCNMGNATGMGNCAYCCNGGNGTNGTNATHYTNAGYATHYTNYTN TGGTTYCAYCCNYTNATGACNYTNGAYMGNGTNYTNYTNGCNTCNGTNTTYACNACNTAY ATGGTNTGGMGNCAYCARYTNGAYGAYACNCAYTGYCARTAYGCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGGGAYAGY AARAARGTNGCNMGNTGGATHTCNTCNATHGGNATGGGNCARTAYTCNAAYYTNTTYATH GAYTTYCAYGTNGAYGGNATHCAYYTNYTNACNACNGAYAGYYTNACNATGGARMGNATG GGNATHAAYAAYGGNCAYGAYGTNYTNTAYATGGARACNMGNATHMGNGARYTNAAYAAY TCNAARMGNYTNTCNATHTGYCAYATHGARGTNYTNCCNCAYTCNTAYTAYMGNGCNYTN AAYTCNGGNMGNGARCCNCCNCCNMGNTAYYTNGGNGARYTNYTNCAYTAYTGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATGGAYAGYGAYATGGARATHYTNGGNYTNTAYCARCCNCCNYTNGAYTGYCCN AAYGGNMGNTGYGAYGTNATGGTNACNTCNTTYYTNTAYTGYTTYTCNATHCCNGTNGCN GTNATGATHGTNTTYYTNGTNYTNYTNGCNGTNGTNATGTGYTGYTCNMGNMGNGCNTGY ACNTGYAARAARTAYTCNTCNYTNACNTCNGAYGCNAAYGGNATHCARATGGARAGYTAY AAYACNATHMGNMGNGCNTCNGCNAGYYTNMGNTAYATGTCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNGGNCAYYTNCARACNGGN GTNCCNCCNCARYTNTTYCARCARGTNGTNTCNACNAAYGTNATHACNTCNACNCARTCN GAYGCNGCNACNGTNTCNACNAAYTAYGARGAYCCNGTNTTYTCNTAYAGYTGYYTNATH GCNYTNGCNTCNYTNAAYAARTGYTTYGCNAARGTNGAYAAYCCNAARATGAGYCARGGN GCNAARAARGGNTGYYTNTGGGCNYTNAAYCCNGCNAARTAYAAYGARTAYYTNGGNTAY YTNYTNCARATHYTNATGYTNGAYGTNAAYYTNGTNGTNTTYATHGARCCNAARGGNACN GGNTTYGTNAARAARATGMGNMGNGGNMGNGARGCNMGNACNYTNATHGTNCCNACNGAR YTNTCNGAYYTNGARTAYTTYCCNYTNYTNCCNMGNATHMGNTCNATHATGAAYAGYATH TCNTTYCARACNGAYAAYACNAAYTAYCARMGNGGNYTNCCNGARGGNACNGAYCCNYTN TAYAAYYTNGTNACNAAYTCNAARACNACNYTNGTNCAYMGNGCNGTNGTNTCNAAYCCN TTYAAYTCNGAYTAYTTYGTNTGGATGGAYGGNGGNTAYGGNCAYGGNGAYTCNMGNATH TTYCCNCCNGAYMGNGTNTGGTGYCCNCAYCAYYTNYTNMGNCAYCCNGAYAARGTNTCN TTYATHGCNTTYGARAGYYTNAGYGGNGARMGNGCNGARACNGARACNYTNCAYAARCAR AARACNGCNTGGATHGCNGGNGGNYTNTTYTCNGGNGGNMGNGCNTCNATGGARMGNTTY TAYTCNYTNCAYAARGAYACNYTNTGGAAYTAYATGAAYAARGGNGTNATHGAYGAYGAY CARACNACNTTYGTNGAYTGYGTNATGAARGAYCAYTAYAAYTTYMGNCCNGTNYTNGGN GAYTGGTAYGAYYTNATGAARCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TGGMGNACNAARTGYATGAARYTNGARAARGTNATHAARACN YTNTCNAAYCAYTGYGTNAARGTNGTNGARCAYCAYGARGAYYTNYTNGTNAARTTYAAR AARAAYCARGAYCARTAYGARMGNYTNAARCARAARTGYAARGAYMGNGGNGGNCARATH AARCARGCNMGNGAYGTNYTNATHCCNGTNTCNAAYGARYTNAARYTNYTNMGNGARAAR TAYGARGTNGCNGTNMGNTGYCARATGGARGCNGARTCNTTYGCNATHGARACNACNAAY AARAAYAARAARYTNCAYMGNCARAGYCARGCNYTNACNGCNCARYTNGGNAAYGTNAAY ATHGTNGAYATHAAYATHGAYGAYGAYGTNGARCARGGNGCNGARGARAARAARTAYATH GARAARYTNGGNCARAARATHGAYGAYYTNGARGARGARMGNAGYACNYTNCAYATHCAR ATHAARGARATGACNGARAAYTTYCARGAYGARTGYACNACNAAYGTNMGNYTNMGNGAR MGNATHGARTCNYTNAARGARGARYTNCARCARGCNAAYACNACNATHAARGARCARACN GARYTNYTNCARAARGTNGCNGTNACNTCNGARATHGCNTTYAARGARTAYCARGAYATG GARCARACNTAYAARAARGARTAYATGGTNMGNAAYGARGCNGARMGNTTYGCNAARMGN YTNTTYACNGARMGNGAYCARGCNMGNMGNGARAGYTCNATGGCNYTNAGYAARGTNGCN GAYAAYAARAARYTNATGGARGCNATGYTNGARATHCARGAYYTNAAYGCNCARATHGCN CARATGMGNGARGAYTTYGAYAARCARACNYTNGCNTCNGARGARCARYTNAARGCNGCN AARGARGTNTAYAAYGTNGARAAYYTNGARGCNGARAAYGARGARYTNAAYGCNGARAAR ACNACNYTNCARCARAARYTNGARAARAAYGARGCNGARATGACNAGYYTNMGNGCNCAR TAYACNGAYYTNCARGARACNTAYAARGCNYTNGARACNAARTAYGARAARGCNACNGCN GTNCCNCCNCCNCCNGCNCCNCCNCCNCCNCCN------CCNGCNGTNAARGTNGGNGGN TTYYTNCARAARATHGTNGGNMGNMGNGGNCARMGNGAYMGNGCNAARGARCAYYTNAAR AARGGNGGNGTNGARYTNAAYGAYAAYCAYACNAARGCNGTNGAYGARATGATGAARMGN ATHAARAGYGGNAAYATHGGNYTNMGNCCNGCNCARCARMGNMGNACN---------CAR TCNYTNCCNGARAARGAYGARCCNAGYGCNATGAAYGARYTNCARGGNYTNYTNAGYAAR ATGAARMGNGCNAARAGYGARGAYGAYYTNTCNGTNTTY---GARGARAGYGGNGTNAGY GARGAYTCNGARYTNGGNAARATHTTYAARMGN---ATGCAR------------------ ---------YTNAGYCARGAYGCNCCNCCNGARACNGARMGNTCN--------------- ------MGNCCNGTNCCNGCNCCNMGNAAYYTNTCNACNATHCARGAYGARGAYGAYGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNCAYCARATGACNGTNCCNTCNYTNAAYATHTCNYTN AARGARGGNGARAGYGTNAAYACNATHTCNTAYYTNAARGAYAAYATHTGGMGNATGTAY CARCAYATGATGGARAARYTNACNGARGGNTAYACNACNGTNATGYTNMGNGARGGNGAY TTYTAYTAYTCNTAYTTYYTNTGGTTYGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AGYTGGAARYTNCAYGAYATHTAYCAYTAYAAYACNGARGAR GAYTAYAAYTCNGARAAYMGNTAYGCNGARATHMGNGAYGGNGGNGAYTTYCARGAYACN YTNAGYTCNTTYGTNACNCCN---AARAARAARGCNATHAARCCNTTYMGNGCNGTNYTN CCNACNMGNTCNTCNACNAARYTNTTYAGYMGNAARATHTCNAGYATHTCNCCNCCNAAR CARGCNGARAGYAAYAARTCNACNTTYAARCAYCCNCAYGGNAGYTCNAGYAGYAGYAGY CARMGNAARMGNCCNYTNTCNTCNYTNACNCCNGAYTCNGCNTAYCCNCCNCARTCNTCN CARMGN---TCNAAYAGYAGYGGNCARMGNMGNCCNGCNTCNTTYGCNAAYCCNGAYGTN GAYCAYCCNACNTCNACNAGYATHACNAGYAGYAGYCAYMGNAARCAYYTNACNCCNGAY YTNGAYTCNACNCARCCNTCNAAYAAYGCNGGNAAYTTYMGNMGNAARMGNCCNACNTCN TCNTCNTTYACNCCNAARYTNGARCCNAGYMGNCCNTTYAARTTYGCNAGYACNCCNTCN CCNAAYCCNYTNTCNTCNTCNTCNTCNYTNAARTCNGARTTYGARCARCAYTCNTCNTCN TCNTTYTCNTCNCAYAARMGNGTNCCNTTYACNACNGTNYTNGAYATGCCNGARTCNGGN GTNMGNMGNTCNCCNMGNAARYTNTTYGARAARTCNGTNAARGCNTCNAARCCN------ ------ACNGARTCNTGYCAYMGNAGYGARAAYGCNGGNCCNTCNGARACNACNGARTCN ACNCCNACNACNAGYATHMGN------------------------------ATGAARMGN TCNGARMGNCAYATGATGMGNYTNAARAGYATHATHGCNAARGTNYTNACNGARAARGGN GTNGARAARGAYAAYGCNATHTAYCARGCNTGYTCNAARAAYYTNYTNAAYGTNAGYATH GTNYTNYTNAARAGYYTNCCNAAYTCNMGNAAYYTNACNGAYGARATGAARTCNGTNGTN TAYGGNCARGTNCARCARATHATHAAYYTNGARAARMGNMGNTCNGGNATHGCNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TTYTTYYTNTGY---TTYGTNTTYYTNCAYMGNNNNNNNNNNNNNMGNNNN MGNNNNMGNAGYMGNGARMGN---------MGNAGYMGNGARMGNAARTCNMGNAGYMGN AGYAARGARMGNMGNMGNMGNGARGARGCNGARAARGGNGGNMGNMGNMGNAGYGGNAGY MGNAGYMGNGARMGNMGNMGN---MGNAGYMGNAGYAARAGYMGNMGNMGNAARAAYAGY MGNAGYMGNAGYMGNGAYMGNMGNMGNAARAGYMGNTCNCCNMGNMGNMGNTAYAGYMGN AGYCCNYTNMGN---GARMGNYTNCCNGARYTNACNGTNGARGARMGNGAYGTNMGNACN ATHTTYTGYATGCARYTNTCNGCNMGNATHMGNCCNMGNGAYYTNGARGARTTYTTYTCN TCNGTNGGNAARGTNMGNGAYGTNMGNYTNATHACNGAYAAYAARACNMGNMGNTCNAAR GGNATHGCNTAYGTNGARTTYGCNGAYCCNGARTCNGTNACNYTNGCNATGGGNYTNACN GGNCARAARYTNYTNGGNGTNCCNATHATGGTNCARCCNTCNCARGCNGARAARAAYMGN GCNYTNCCNGCNACNCARGCNCCNACNCARAARCAR---GCNCCNGARGGNCCNYTNMGN YTNTAYGTNGGNTCNYTNCAYTTYAAYATHAAYGARGAYATGYTNMGNGGNATHTTYGAR CCNTTYGGNAARATHGTNGAYATHAARATHATGMGNGAYCAYGAYACNCARMGNTCNYTN GGNTTYGGNTTYATHAGYTTYGCNAAYGCNGAYGAYGCNAARAARGCNYTNGAYCARYTN AAYGGNTTYGARYTNGCNGGNMGNCCNATGAARGTNGGNCAYGTNACNGARMGNACNGGN GARCARGGNCARGGN------GCNCARAAYGGNGTNGGNGGNCARYTNGAYACNGAYGAR ATGGAYMGNGCNGGNATHGAYYTNGGNGCNACNGGNMGNYTNCARYTNATGGCNAARYTN GCNGARGGNACNGGNTTYCARATHCCNCARTAYGCNGCNAGYGCNYTNAAYAAYATHACN CCNGCNGCNGCNTCN--------------------------------------------- ---GGNGTNCCNGCNACNGCNCCNGCNGCNCCNGTNGCNATGGCNATGGCNCCNGCNCCN CCNGCNGCNACNAAYGCNCCNCCNATHGCNACNCARTGYTTYATGYTNTCNAAYATGTTY GAYCCNACNTCNGARCCNMGNYTNACNTGGGAYCARGARGTNMGNGAYGAYGTNATHGAY GARTGYAAYAARCAYGGNGGNGTNYTNCAYATHTAYGTNGAYAARAAYTCNCCNCARGGN AAYGTNTAYGTNAARTGYCCNAGYATHTCNGCNGCNGTNGCNTCNGTNAAYTCNYTNCAY GGNMGNTAYTTYGCNGGNMGNGTNATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARCCNCCNAAYYTNAARATGMGN GARGARATGATGCARAARAARAAYAGYAARAARACNACNTCNTTYATHGAYTTYGAYTAY YTNGAYTCNYTNATHTCNACNAAYGCNAGYCARTAYGCNTCNACNATGTCNYTNGCNCAR TCNACNTCNAARTCNTCNACNACNTCNAAYYTNGGN---CCNGCNMGNAARCCNMGNATG CAYGCNMGNATHAGYAAR---CARCAYAARCCNYTNTTYMGNACNTCNTCNCCNAAYAAR ACNCAYTCNCCNAAYTCNACNCARGAYTCNAAYYTNATHGAYGTNGTNGCNGAYGCNCAR TCNAGYCCNMGNGTNAARGGNMGNGAYACNAAR---MGNGGNAGYGAYGCNYTNACNCCN GGNMGNGAYATGAARMGNCARAGYGAYGCNYTNACNCCNATHMGNGARATGACNAGYGAR GAYGARGARGAR------GGNAARAARTTYTCNCARGTNTCNATGAGYCARATHMGNGAR AGYMGNAAYAARAARGARCAYGTNATGCARTCNCAYCCNATGGGNMGNGGNTGYGARTTY GTNMGNACNGCNTTYAAYGTNGARGGNMGNAGYCCNYTNGTNGCNCAYTTYYTNAAYATG AARGGNYTNACNCARGAYGTNGGNCARAAYATHTGGATHCARMGNGTNGARGTNGAYGAY YTNCCNCCNYTNGAYGCNACNACNTAYAARGAYGTNATHAGYGARTCNTCNAARACNATH MGNAARYTNGARTCNGGNTTYCARGAYYTNTAYYTNAARAAYTAYAARCAYAGYCARYTN TTYATGMGNCARCARCARAARATGYTNMGNGARCAYATGCAYAARCARTCNGCNYTNYTN GCNAAYAARGAYGARGTNAARGTNYTNTGYGAYYTNATHATHYTNGARCARMGNAARAGY CARGAYTCNGTNTCNGCNGGNGCNGCNGCNGCNATHGARGCNGCNYTNATGGCNCARGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGAYCCNGTNTCNCARACNYTNGCN AGYGARCARATHGARGAYGTNGGNATGTCNGTNGTNGGNTGGTAYCAYTCNCAYCCNACN TTYAGYCCNGAYCCNTCNGTNMGNGAYATHGARACNCARCARAARTTYCARTAYTGGTTY TCNAARGGNGGNAAYCAYTTYGTNGGNATHATHATHAGYCCNTAYAAYACNTCNTGYCAY TCNACNTTYTCNGAYATHMGNTGYYTNACNATHAGYGAYGARCAYAGYCCNGAYTTYYTN TGYAAYATGCCNTAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CCNGARGTNCCNCCNYTN GCNGARTCNTGGGCNYTNCCNATHAAYCAYYTNTGGCARTTYGCNAAYCAYGAYGGNGAY GCNGTNAARATHTTYAAYMGNYTNATGTCNTTYMGNAGYCCNCAYTGYTCNGTNTGYTCN YTNTTYAAYAARTTYAAYCCNGAYGARGARTGGTCNGTNYTNCARGCNMGNATGATH--- ------GGNGGNACNATHCCNCCNMGNTCNYTNCCNATGATHCCNGARTCNTCNTTYGCN GTNAGYGTNTCNAAYMGNACNCCNTTYTGYGAYTAYTCNCCNGTNGAYGARGAYGGNYTN AGYTCNYTNYTNYTNTGYTCNTCNTGYAGYATGTGYGTNCAYGCNAGYTGYTAYGGNGAR TTYMGNAARATHCAYCCNCARGAYTGGAARTGYGAYGCNTGYATHTCNATGGARCARTCN GGNGAYCAYGARTGYTCNYTNTGYTAYYTNMGNGGNGGNGCNYTNAARCARACNACNGAY GGNCARTGGGCNCAYGTNGCNTGYGCNYTNGCNATHAGYGAYGTNTTYTTYAARAAYATH MGNTAYMGNGCNCCNATHGTNACNGARAARATHGAYMGNGARMGNTTYAAYYTNAARTGY TCNYTNTGYGGNCCNGTNTCNCARCAYGCNAAYGAYACNMGNCCNTGYATHCARTGYTCN CAYGGNMGNTGYACNACNGCNTTYCAYGTNACNTGYGCNTTYATGGCNGGNATHAARTTY GARATGAGYGAYTGGCCNGTNCCNATHTAYATHTCNTGYMGNAARCAYATHACNACNMGN CARAARGTNGAYGCNMGNMGNGAYATGCCNGAYYTNGARYTNYTNAGYTGGGCNYTNGCN AARCAYAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATHCCNCARGGNYTNGCNTAYGCNCAR ATHGCNCARYTNCCNCCNCARTAYGGNYTNTAYTCNGCNTTYATGGGNTGYTTYGTNTAY TGYYTNATGGGNACNTCNAARGAYATHACNYTNGGNCCNACNGCNATHATGTCNYTNATG ACNGCNACNTTYGGNGTNCCNCCNATHCCNGAYCCNGAYGCNACNTTYGCNATHGTNYTN ACNYTNATHTCNGGNGTNGTNCARTTYACNATGGGNGTNYTNAARYTNGGNATHYTNGTN ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGCNACNCCNGARGTNCARAARYTN YTNGAYYTNCAYAARTGYYTNGTNTTYGAYACNGGNACNCARAARATHAARTGYAGYYTN ACNAAYCAYGARATGCCNGCNAARGTNAGYGCNATHGARAGYTAYGTNAGYGGNAARAAR TAYAARMGNYTNGCNGCNTTYAAYYTNTTYTCNTAYGARGARCAYAARGARCAYATHGTN CARAAYAARAARAARGAR------CAYGARYTNTTYTGYAAYYTNACNCAYMGNCAYYTN GARAARACNGCNACNGCNATHCARMGNCAYATHAGYGGNMGNAARTAYAARAAYGCNYTN GCNMGNTGGAARGARTGYCARAARACNGGNTCNAAYTTYACNCCNMGNAAYCARMGNAAR TCNAARGTNCCNCARYTNAAYGAYGAYGAYGARGARGARAARGAYGAYGAYAARAARAAY GAYGAYAAYGCNAGYGGNAGYGAYGAYGAYGCNGGNAGYGAYGGNACNGTNGTNGAR--- ------------------GAYGARAGYGCNGAYGAYGAYGARGAYGARGAYGAYGAYGTN GAYGAY------------------------------------------------------ ------------------------------------------------------------ ---------CCNYTNCCNCCNGGNAGYATGGGNTGGCCNATHATHGGNGARACNATHCAR TTYYTNATHAARGGNACNGARTTYTAYACNGARAARTTYAARCARTAYGGNAAYATHTTY AARTGYAAYATHYTNGGNAGYCCNACNATHMGNGTNACNGGNGCNGARAGYATHMGNACN YTNGTNGAYMGNGARCCNAARCARYTNACNATGAARTGGCCNACNGCNGTNAAYGTNYTN ATGGGNMGNAARAGYYTNCCNACNYTNGTNGGNCCNGARCAYGCNGTNYTNAARGARCAY YTNCARAARGCNTTYACNCCNACNMGNYTNGCNGAYTAYTTYTCNTGYGTNCARGARCAY YTNGAYGCNCAYGTNCARATGTGGATGAGYGARGGNGARGARAARAARCAYGTNYTNGGN TTYCCNGCNTGYGARAAYATGATHGCNGAYATHATGYTNGARYTNGTNYTNGGNTGYMGN AARGARGAYGAYGARGARGGNMGNATHMGNCARGCNTTYAARGAYATHAAYCAYAAYYTN ATHACNGTNCCNATHMGNTTYCCNTTYAGYGGNTTYAARAARGCNTGYGARGGNMGNGAR ATHATHYTNGAYTTYGTNGARTCNCARATGCAYGGNGARGGN---AAYAARAARCAYGTN AAYATGATGGAYGTNATGYTNTCNTTYCAYGGNGAYGARAAYGGNGTNATGGAYCCNGAR AARGTNAARGAYAAYGCNYTNGGNATHATGYTNGCNGCNTCNTCNAGYACNTCNGGNGCN YTNACNATHYTNATHYTNYTNYTNGGNACNCAYCCNGARGTNYTNGARAARGTNMGNGAR GARYTNAARGARTTYGGNYTNTTYGGNAARGAYTCNACNGCNGARYTNAGYTAYGAYYTN YTNGGNAARYTNGARTAYGTNCAYTGYGTNATGAARGARTCNYTNMGNTTYYTNCCNCCN GTNGGNGGNTGYTTYMGNAARACNGARAAYCARATGGTNYTNGAYGARTAYAARATHCCN AGYGAYTGGACNATHATHTAYAGYATHMGNGAYACNCAYYTN---ACNTCNAARYTNYTN CCNGARGGNGAYTCNTTYYTNCCNTCNMGNTGGATGAARCARGARCARGTNCARCARGGN GGNAARGARACNCCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNYTNGCNGCNTTYMGNAGYYTNCAYMGNGCNMGNAAR GARGTNTTYGCNGGNGAYGARAGYGCNYTNAARGARGTNMGNCAYCARATHAAYTCNCAR TTYMGNGARAARYTNYTNGARACNGAYGARTCNAARATHGARGARAAYYTNGTNYTNGCN AAYGAYGTNGCNTAYYTNYTNMGNTCNACNGTNGTNCARYTNCARCARAARCARGCNGGN GAYGAYACNTAYGARYTNMGNATHACNGARAAYACNTAYYTNCCNGARAAYACNCCNTTY GAYCCNACNAARGARATGCCNYTNAARCARMGNAARAARAARAAYGCNGAYTGYTCNGAY TCNACN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNGARTAYATHGTNGARTCNGAYGAYGGNAARATHGGN TCNMGNATHGCNYTNAAYYTNACNGARAARYTNGARAARMGNATGGGNAARGARGARGCN CARAAYTTYYTNAAYAGYYTNGARAAYGARAARTGGATHGTNAARGAYGARAAYGGNAAR ATHTCNYTNTCNGTNMGNAGYYTNYTNGARYTNGAYCARTAYYTNCARGAYATGTAYCCN GAYYTNATHAARAAYTGYAAYATGTGYAGYAARYTNTGYATGCARGGNGAYTCNTGYYTN AGYTGYGGNATHMGNATHCAYYTNAARTGYTCNAARACNTTYTTYTCNAARCARACN--- GAYAARAARTGYCCNAGY------TGYAARYTNCCNTGG------------ATHCCNAAR GARAARYTNTCNACNTCNGAYAARGGNAAYGCNCAYAARGAYTGGGTNMGNYTNAARTTY ACNATGCARGTNAARTAYCARGGNGCNACNAARTCNYTNYTNYTNYTNTCNYTNCCNTTY AAYATHMGNAARGGNTCNGTNCARATGTAYACNTTYATHGGNGCNYTNATGTGGTAYTAY ATHACNGCNGAYCCNTAYAAR---GARTTYAGYGTNAARACNMGNYTNCCNACNTCNACN TTYYTNGAYATGYTNATHGCNMGNYTNGARTAYATHGGN---------MGNAARYTNTCN TCNGARGARACNGCNTTYTTY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARYTNGAYATGYTNYTNTCNTCNCAY MGNGARGARGTNMGNMGNGAYGARATHCAYCARAARATGAARGARGARYTNYTNCAYTCN ATHGARCARGGNTCNCARGGNGAYTCNYTNACNGGNGARTTYGCNGARMGNATHGARCAR YTNGARGTNACNACNCCNGTNYTNYTNACNGAYCAYCCNAGYATHACNGTNTTYAGYCCN GAYAARTTYTGYTGYYTNTTYAARGAYAAYATHAAYCCNTTYTCNTGYGGNTTYTCNMGN TCNCAYTTYTCNAARATHGAYAARGTNTTYGCNACNTTYMGNTCNGARAAYYTNATHCCN YTNYTNYTNTCNAGYACNYTNCCNTCNTGYTTYCAYCARGTNTCNAGYCCNCAYTCNATH ATGATGTGGYTNYTNAGYYTNYTNTCNATHCAYTCNTCNTCNATGGTNGTNAAYYTNATH CAYCARAAYATGACNAGYATHATHCARAAYTTYGGNAAYCAYMGNAARGGNGAYGARGAY GARTCNGCNGAYAARTGGTGYCCNAARCCNATHGARATHACNMGNATHYTNGTNAAYATG GGNGCNAAYCCNGTNTAYYTNYTNGGNAAYCARGCNYTNTAYTCNACNGARGAYATHAAR GARCAYYTNTCNGTNGARAAYGAYGARAAYGAYTAYACNCCNACNAARTCNTCNGGNMGN GTNAARGTNGARAAYTGYMGNTGYGTNTTYGARATHYTNACNMGNTAYTTYCARACNAAR CCNGCNTAYACNAARGARGARACNAAYYTNATGGTNTGYYTNATHACNAARGTNTCNYTN GAYTCNTCNTTYCARAAYTTYGARYTNCAYCAYGTNTTYCARGAYYTNYTNTCNTCNYTN YTNGARTGYTAYACNGAYTCNGARTGGTTYTCNGTNGTNCCNTCNYTNTGYCAYGARTTY AGYACNATHCCNCARCAYCAYCAYTGYTCNGTNTAYYTNGTNGAYYTNATGCCNYTNAGY GCNMGNGGNAAYTAYATHCARATHMGNYTNAGYTTYYTNYTNYTNTGYACNACNYTNGAY TAYGARMGNAARGAYGARCAYTCNYTNCARYTNGAYTCNATHTCNCCNTCNMGNATHTCN CARYTNGGNMGNGGNTCNAGYGARGAYCARCCNTCNTCNTAYYTNTAYTCNTGYYTNCAY MGNYTNATHAARGARAAYGTNAGYATGATGAAYTCNGCNATHACNYTNYTNGAYMGNGCN GTNGGNGAYGARACNAAYMGNAAYGCNCARCCNAARGAYGARYTNGAYTTYYTNACNAGY CARGTNMGNATGGTNATHMGNGAYATHMGNGAYAGYATHAAYAAYYTNGAYYTNTCNAAR ATHAARGAYMGNATGACNATHATGACNAARAARTGGATGATGATGTCNACNCARCAYACN AARAGYGTNCARMGNAGYATHTTYTCNTGG------GTNACNTCNCAYATGAGYGTNCAR GARGARAARYTNAARGAYAGYGTNTCNAGYGAYGCNGAYGARGARATGGAYATGAGYGGN MGNAAYMGNAARGTNMGNGTNTGGGGNMGNYTNMGNCCNACNGCNAAYTTYGCNTAYGAR AAYGTNGARGTNYTNCCNGAYAAYAARGGNATHAAYATHCAYATGMGNMGNGAYCCNAAR AARGGNGTNGTNAAYAAYCARATHYTNGAYTGGTCNTTYAARYTNGAYGGNATHTTYAAY AAYGCNGAYCARGARGTNGTNTAYAAYACNGTNACNTCNGAYGTNGTNTCNGGNTCNYTN GAYGGNTAYAAYGGNACNYTNATGTGYTAYGGNCARACNGGNGCNGGNAARACNTTYACN ATGACNGGNGCNACNGARAGYTAYMGNCAYMGNGGNGTNATHCCNMGNGCNATHTCNCAR YTNTTYMGNCARATHGARGAYMGNYTNGARTAYAGYATHACNGTNMGNGTNTCNTAYATG GARATHTAYAAYGARCARATGTTYGAYYTNYTNGGNACNTTYCCNGARGCNAGYTGGTCN AAY------AARGAYATHAAYTGYAGYCCNGAYCCNATGGTNATHTCNGARAAYCARGGN GGNGTNTTYGTNAARGGNYTNTCNTGYCAYYTNGCNCARAAYGARGARGARGCNYTNAAY YTNYTNTTYGARGGNGARACNAAYMGNTCNATHGCNGCNCAYTCNYTNAAYAARGTNTCN TCNMGNTCNCAYTGYATHTTYACNGTNTAYATHGARTCNMGNTCNMGNGTNCARTCNAAY GCNAARTAYACNGTNTCNAARYTNAAYTTYGTNGAYYTNGCNGGNTCNGARMGNYTNAGY AARACNAARTCNGARGGNAARACNAARGARGARGCNATGTAYATHAAYAARTCNYTNTCN TTYYTNGARCARGTNGTNATHGCNYTNGCNTCNAARACNMGNGARCAYGTNCCNTTYMGN CARTCNAARYTNACNCAYTTYYTNAARGAYTCNATHGGNGGNAAYTGYAAYACNGTNYTN ATHGCNAAYATGTGGGCNGARAARCCNCARATGGARGARACNGTNTCNACNYTNMGNTTY GCNACNMGNATGATGTGYGTNGCNAGYGARCCNGCNGTNAAYGARATHTAYGAYCCNGCN YTNYTNGTNAARAARYTNCARAARGARATHTGYCAYYTNAARTCNGARYTNGCNATGCAY GAYACNYTNACNAAYMGNAGYATGGTNTCNTAYGAYCCNYTNTCNGARCARCARAARTAY GARATHMGNACNCARGTNMGNMGNTTYYTNGARGGNAGYYTNGAYGARATHGAYATHGTN AAYYTNMGNCARATHGTNGGNTGYTTYAARACNTTYAARGAYYTNTAYCARGAYATGGAR AARGARATGGARGCNAARYTNMGNGARMGNTAYATGYTNATHGAYAARACNGAYCCNAAY TCNATHGCNGCNGCNCARCAR--------------------------------------- ------GCNGGNATHCCNATHGCNGAYGAYGGNACNTAYGTNGGNGAYYTNGARGGNGGN GGNTTYGGNATHGGNTCNGCNCCNAARAGYGCNAARGGNGAYAGYTCNGCNGTNGTNCAR YTNMGNAARAARGARMGNGARMGNGARMGNAARMGNGGNTCNMGNGGNGCNAAYAGYCCN ATHGCNGGNAARACNTCNTCNAGYCCNTCNCARAGYGTNAARGGNGARMGNAARGCNGAY TCNCCNCCNACNCCNGGNGGN------GGNGARMGNGTNGARAARGAYCARGARGGNTCN GCNTCNCCNGTNAGYTCNACNGGNAAYYTNTCNMGNGCNGAYMGNAGYCARMGNCCNAGY ------------------------MGNCCNGCNGTNGARGARCCNGARNNNACNCCNCCN TCNMGNAGYGCNGCNTTYGARGARTTYAARAGYGAYMGNGGNTGYGARATHAAYMGNATH YTNATHGARAAYAARGARTTYYTNGCNAAYTCNAARAARACNTAYTCNGARYTNGCNAAR CARATGAAYACNYTNAARGTNAAYATHGAYGGNTCNMGNCARMGNYTNGAYGARYTNAAR GARTCNMGNGARTCNGARGGNCCNATHYTNAAYGARGAYGGNGAYATHGTNATHAGYGAR GAYGARTTYAARGARATHACNAARYTNMGNGARYTNAARACNTCNTAYMGNACNAARMGN GAYGARYTNGCNAARACNGARTCNGARGTNAARTAYTGYCARAARYTNGTNGAYCARTGY MGNYTNAARYTNATHCARGARTTYGAYAAYTGGTAYAGYGARAGYTTYYTNAGYGCNACN GARGARGCNCARACNAGYYTNGGNGTNGGNAGYGGNGTNMGNCCNGGNGTNATGYTNCCN ATHACNAGYYTNACNAAYGARGAYGARCARGARAARTTYGARMGNGTNCARYTNGARYTN ATGATGAAYAAYCCNGARTCNGCNGCNTTYTAYAAYGCNCARATGMGNACNTCNMGNMGN AARATHTAYGGNGCNGCNYTNAAYCARCCNCARCCNGCNTTYMGNMGNCARGCNGGNACN CCNACNATGACNTTYMGNAAYCARCCNCCNGGNYTNATGCARGTNCARTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNTCNTGYACNTTYCARTGGAGYATHTCNAAY TAYTCNAARAARYTNGARAAYGARAARAARGGNAARNNNACNAAYACNGTNTCNGARCCN TTYTAYATHGGNCAYTGYGGNTAYYTNGCNMGNYTNGARGTNTAYYTNAAYGGNAAYGAR ACNGGNTAYGAYMGNTAYATHTCNGTNTTYYTNMGNGTNATHAARGGNGARTAYGAYGAY YTNYTNCARTGGCCNGCNAARYTNTCNGTNGCNTTYGTNYTNATGAAYCARGGNCAYGGN TCNAARAARCAYYTNATGTGYCAYGCN------------GTNTTYGAYTAYGAYCARCCN TCNGGNGAYTCNTTYAARGGNAGYACNTCNTGGGGNYTNGTNGARTTYGTNTCNCAYTCN GAYYTNCARGARGAYATGTTYATHAARGAYGAYACNATH------------------ATG GAYTTYGAYTCNTCNGCNAARTTYATHTCNTCNYTNGCNAARTTYYTNCARTCNYTNTGY AAYGGNTAYGTNGARTTYGAYAAYGGNGTNGARGTNATHGGNCAYATHTAYYTNAAYGTN GAYACNGGNAARAARATHGAYTAYGTNYTNAAYGARAARGTNTGYAARACNGAYGARAAY AGYGTNACNTTYATHAGYAAYAGYTTYCAYGCNCARCCNGCNGARAARCCNAARCCNGTN ------------GARAARCCNAARCARAARGCNCCNATHGARCARGAYAARGAYGARATH ATHGTNATGGAYGAYYTNGAYCARGAYTAYAAYGARCARCARTAYAGYAGYGAYCAYAAY TCNACNCCNCARCCNAARCCNYTNMGNTCNCAYGGNGCNTCNAARMGNTCNTAYAGYCAR TCNATHTCNTCNTAYAAYMGNCCNTCNAARTCNTCNAARTTYGAYTCNTCNTCNACNAAY CCNAAYGGNGCNCAYATHACNTCNAAYAGYTCNTTYAAYGTNGCNGGNAAYATHACNGCN ------------GCNACNGARTCNGAYYTNTCNCAYYTNTCNCARGTNTTYCCNGARAGY ATHGAYCCNTCNAAYTCNCARGGNGAYATHAARCCNGTNYTNGAYAARGAYYTNAAYGTN ATHGAYGTNAARCARGARTAYGAYCCNTCNGCNGAYGAYGAYCARGGNGAYGCNAGYTAY TAYTCNCARGAYCARTCNTAYGARTCNMGNAAR------TTYCCNATGTAYYTNGTNGAY GCNTTYACNAARAARGCNYTNAGYGGNAAYCARGCNGCNATHTGYYTNGTNCCNTCNGAY GTNACNYTNTCNGARGAYGARATGCARAARATHGGNTCNGARATGAAYYTNTCNGARACN GCNTAYATHCAYGTNYTNGAYAARGAYGCNGAYTTYAARTCNGGNAAYAARTTYTCNYTN MGNTGGTTYACNCCNACNAARGARGTNAAYYTNTGYGGNCAYGCNACNYTNGCNTCNGCN GCNGTNYTNATHGAYGGNGTNGGNAAYTCNAAYMGNGTNATHGAYTTYTCNACNAARAGY GGNACNYTNTCNGTNAGYMGNCAYCCNGAYAARACNGGNTTYYTNTCNATGGAYTTYCCN AAYAAYAARCCNGTNGCNCARAAYACNGARAARATGGARAARYTNATGYTNAGYYTNGTN AGYGAYYTNGAYATGATHCARGARGTNCARTAYTCN---GCNACNACNAARAARYTNGTN GTNMGNYTNAARGAYCAYATHCAYMGNAARGARYTNGARMGNYTNAGYCCNAARGCNAAY GCNYTNATGGARGCNGARCARTCNGGNATGGTNATGGGNGTNGGNGTNACNYTNAARGGN TGYCAYGCNAAYGGNTGYGTNGAYGARGARGGNAAYGTNTAYGAYTTYGTNTCNMGNTAY TTYGCNCCNTGGAAYGGNATHCCNGARGAYCCNGTNACNGGNTCNTGGCAYACNGTNATH GGNCCNTAYTGGGCNACNGARYTNGGNAARACNATGYTNTAYGCNMGNCARTGYTCNCCN MGNGGNGGNGAYYTNTGYGTNGARGTNAARGAYGARMGNGTNACNYTNATGGGNCARTCN GTNATHAAYYTNGARGGNACNTTYCARYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATGMGNTTYACNGGNYTNCAYGGNAARTCNGAYATH CCNTCNMGNACNTTYGAYMGNYTNAARAARTCNACNCCNGARGAR--------------- ---AAYGGNCARGAYGAYCCNCAYATHGARGAYGARTCNGAYGGNGTNGGNAAYTAYAAY GARGCNTCNATHMGNTAYACNGGNAARAGYATHCCNTCNCCNGCNTTYMGNGTNYTNCAR ACNTGGGCNGARCAYGAYCCNGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GGNTAYTTYAAYAGYTCNTTYAGYATHYTNGCNATG AARYTNATGGARTAYGGNTCNYTNYTNGAYYTNGTNAAYATGTAYAARTCNGAYCCNAAR YTNATGGGNCAYGTNGARCCNTTYGTNTGYYTNGTNACNGTNGARYTNYTNCAYATGTTY GARCARYTNCAYAARTGYGAYATHATHCAYGGNGAYGTNAARCCNGAYAAYTTYYTNYTN ATGGAYYTNCCNYTNGTNTGYAAYAGYCARAGYCCNYTNGARGTNTTYGGNCCNCARYTN MGNGTNTTYTGYYTNACNGAYTTYGGNCARACNATHGAYATGCAYATGTTYCCNTCNGGN ACNTCNTTYMGNACNAARACNAAYACNGAYGGNTTYGARTGYATHGARATGAARAARGAY MGNCCNTGGACNTAYCARGCNGAYYTNTTYGGNYTNGCNGGNACNGTNCAYGTNYTNYTN TTYGGNTCNTAYATGAARGTNTTYGTNGARAARGGNGTNTGGAARATHACNGGNAAYTTY GCNMGNAARTGGAAYGTNCCNATGTGGAARAARYTNTTYCAYCARYTNYTNAAYATHCAR TCNTGYGAYAGYYTNCCNGAYYTNGCNTCNYTNMGNGCNGARTTYGARGARTAYTTYTGY TCNAGYYTNACNTCNTCNTAYAAYGARTGG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARCAYTGYMGNGTNGARGAR ATHGCNMGNGCNAARTGGATHTGYYTNAAYAARATHATHTAYAARGAYCCNAAYGGNACN GARMGNATHTGGGARGGNGTNTCNMGNACNACNAARAAYGCNGGNGARGCNGAYGCNGTN GGNATGGTNGCNYTNTTYCAYGAYCCNCARACNGAYYTNCARAGYGTNATHYTNATHMGN CARTAYMGNCCNCCNATGGARACNTGYACNATHGARTTYCCNGCNGGNYTNATHGAYAAR GGNGARACNGCNGGNGARGCNGCNGTNMGNGARATGAARGARGARACNGGNTTYGAYGTN ACNGTNGTNGAYGTNTCNCCNGCNACNTCNYTNGAYCCNGGNGTNGGNAGYACNACNYTN AARATHGCNACNTGYAARGTNGAYCARAGYAARYTNAGYAARGAYGARMGNCCNAARCCN ACNGGNGGNGAYGCNGAYGARTTYGTNCARGTNYTNATHCARCCNYTNAAYAGYYTNATG GARAAYYTNAARGAYTAYGCNGCNCARGGNGAYTGYGTNGAYTCNMGNGTNTAYACNTGG GCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GTNGARGARAAYGTN CARAARGAYGARGGNGARGARGAYAARAARTCNGARGCNAAYGAYGAYGAYTCNGARGAR GAYATHGAYTTYGAYGAYYTNGAYAAYATHGAYMGNGTNYTNGARAARGCNYTNGARAAR AARMGNGARGGNAARACNACNGAYYTNCARGARTCNTCNCAYGTNTCNCCNTCNTCNTCN TCNGCNGTNGARACNAARAARACNGARGTNGTNGARGCNGAYMGNCCNGARCCNGTNGAR TCNTCNGTNGAYGGNTCNGCNATGAGYGAYACNGAYATGAARMGNYTNAARTAYACNGTN AARGAYTCNGCNGARYTNGCNYTNAAYAARYTNCARTTYYTNGAYATHTCNACNAARAAY YTNTCNAARYTNCARATHYTNYTNGTNGARYTNCARACNMGNTAYAGYGAYTGGCARTCN GGNGGNYTNTCNACNCCNTAYTTYCAYAARCARYTNAARTCNTCNGARGCNYTNYTNTCN CARTAYGARGARAGYGCNGTNCCNTCNGGNTGGYTNTGYCARTGGGAYMGNGCNAGYTGY MGNTAYTTYTAYMGNAAYGARCAYAGYGGNCAYACNCARTGGGARTAYCCNCARGCNTCN TCNAARGGNGGNGARGTNAARGAYTCNGGNAGYAGYMGNGGNMGNAGYAGYAARAARMGN MGNAGYAARGAYGCNGARGARMGNGGNGARCAYAAYTCNACNAGYMGNAGYGGNMGNAGY CAYMGNAGYAGYAARAARGGNTCNGARAARGAYMGN------GGNAARMGNGAYMGNCAY AGYGGNAGYTCNCAYCAYCAYMGNAARAARAARMGNMGNMGNMGNGARCAYAAYAGYAGY AGYAGYAGYAGYAGYGARGAYGARAGYGGNTCNTCNMGNCAYMGNCAYMGNAGYAARMGN AARAARMGNGGNMGNTCNGAYAARTCNCCNAGYYTNGARGTNATHGAYGGNCCNGAYGAY GTNCARGTNATHGARGAYAGYCCNCCNCCNGAYGARTCNMGNGARTAYMGNAARAAYMGN YTNGAYAAYGAYGTNGGNGAYAGYAAYACNGCNTCNGTNCARTCNGCNTCNGCNACNYTN GGNYTNATHGCNGAYTAYGGNTCNGARCARGARGARATGGARGARGARYTNGARGGNATH GAYGGNGARGARATGGARAARGAYGARGARGGNGARGARGARGCNGGNGGNATHCARGAR GAYGARGARATGAARGARGARGARGARCCNGGNGARGARGAR---------GARGARGTN ---AAYAAYGCNGTNATHGTNAARCCNCCNCARATHATHGTNCCNCCNTAYGTNGCNGCN ATGAAYCARCCNCARYTNTAYTCNGCNCCNGCNYTN---TAYGCNTCNGCNCCNGTN--- ------CCNTCNTCNACNACNACNGTNGCNCCNCCNTTYTCNGCNGARCARGAYCAYGAR CARGCNAGYAARAARAARAARAARGAYAARTCNGGNAARGARAARTCNYTNACNGCNAAY TCNAGYATHATGATGAARAARAARMGNGTNTCNTCNATGGTNCARAARTGGCARCARGTN AARAARGARGTNGARAARGARAAYMGNGAYAARGARYTNAARCARGCNGCNATHMGNGAR AARATHAAYCARYTNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GAYGTNATGYTNMGN YTNAAYMGNATHGCNMGNTAYTGYYTNAARCARACNGGNTTYTTYYTNMGNGTNCARCCN CCNCARGCNCARTAYYTNATHAARGAYAGYGARYTNGARAGYYTNAARGGNGTNTGGGGN CCNAAYGGNATGTGYCARACNGGNGCNGTNMGNACNAAYTGYGTNGAYTGYYTNGAYMGN ACNAAYACNGCNCARTTYGCNATGGGNMGNAGYGCNYTNGCNTAYCARYTNTAYGCNATG GGNYTNATGGARMGNCCNCARYTNGARTTYGAYACNGAYTGYGTNAARYTNYTNGARGAR YTNTAYGARGAYCAYGGNGAYACNYTNGCNYTNCARTAYGGNGGNAGYCARYTNGTNCAY MGNATHMGNACNTAYMGNAARATHGCNCCNTGGACNTCNCAYAGYMGNGAYATHATGCAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TGGTCNCARCCNTCNCCNATGTGGAAY ATGGAYATGATGAAYGAR---AARTCNCARGCNTAYAARATGCAYYTNGARAAYATGAAR MGNGARMGNGARGARGARAARYTNAARGARGARGARMGNATGAARCARGARYTNATHGAR AGYAARCARGARGARYTNMGNAARCARCARAAYGARYTNCARMGNCARMGNGARYTNATG MGNAARGARAARGARGARATGGARAARGARMGNYTNMGNAARYTNGARGARGTNMGNMGN GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARCCNATHAAYCCNGAY GCNGGNAARTTYAAYTAYCARGARCARMGNAARCARYTNGCNGARGARMGNMGNMGNGAR TAYAAYCARATGYTNCARCARAARTCNAAYCCNMGNACNMGNGARMGNGARCARGARATH GAYAAYCCNTCNATHATHCCNTTYAAYMGNCCNGAYCARGARMGNATGAARGTNAARATH YTNGARGARGARMGNCAYMGNGARTAYAAYGARACNYTNGCNAARATGCARGAY------ MGNAARMGNGARGTNACNCCNGTNCCNAAYTTYGAYCCNTAYAAYYTNGARCARGARAAR MGNATHCARAARGARMGNGARCARMGNGARTAYAARGCNATGYTNGAYAARCARCARGAY CAYCARAARCARATGATGYTNYTNCARCARGGNGTNCCNTAYGARAARGTN--------- ------------------------------------------------------------ ------------------------------ATGCARGCNTAYACNCCNCCNYTNTCNYTN TGGAAYYTNGTNGARCARCAYGTNCCNACNTTYGARYTNGARGARGTNAARAGYATHYTN GGNTCNAAYYTNGTNGAYCARAGYYTNGARYTNCAYAGYGARATHGARATGTTYYTNGAY ATHTGGMGNGAYATGMGNGAYGARGTNCARGARAAYAARYTNGTNCARTCNMGNYTNCCN GARCCNCCNAAYCARMGNGARMGNYTNATHCARGARATHAAYTTYTTYGCNGARAAYATH AARGAYAARGCNMGNCARAARGGNATHGAYCCNGARAAYATHYTNAARACNCAYAAYAAY AAYGTNATHGAYTAYGCNTCNGAYGCNAGYMGNCCNGGNTCNTCNATHGGNMGNACNTCN MGNTCNTCNGAYGGNMGNGARACNCCNATGATGGTNGCNTCNCCNGAYMGNATHYTNAAR GCNTAYGARGTNACNGAYGARATHGARGCNTGYAGYGGNCARYTNAAYGTNGAYMGNTTY GAYAAYGTNTGY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GCNATGGCNACNGARYTNTGY AAYAARGCNAAYGARGARTAYGTNGARGARAAYTAYCARAARGCNYTNGAYYTNTAYACN GARGCNYTNGCNYTNGARAAYACNMGNGAYGAYATHTAYTGYTTYMGNGCNCARGCNAAR YTNTCNYTNGGNAAYTCNTCNGAYGCNATHAARGAYTAYGAYGARGCNATHMGNYTNAAY CARAAYAAYCARAARGCNTAYATHAARAARGGNTCNGTNYTNYTNCARATGGGNGARGTN YTNCARGCNCAYGGNGTNTTYAARGARGGNCARAARCAYTTY---GGNGAYAARAAYTTY GARGAYTGGYTNGGNAARGTNGARTGYMGNATGAARGARYTNGGNATHAGYCARTCNTCN CARGTNTCNACNGARCCNGCNGARGTN------------------CCNTCNATHAARCAY AAYTGGTAYCARACNCAYACNCAYGTNATHGTNACNGCNYTNGTNAARAAYGTNAARAAR GARGARYTNGTNYTNGAYGTNGARGAYMGNTCNATGMGNATHAGYATHCARMGNGGNGAY CARTCNAGY---GAYYTNAAYATHATHYTNGCNCAYMGNGTNGTNCCNGARCARACNCAR TCNAARYTNTTYTCNACNAARATHGARATHAARYTNAARAARTCNGARGGNATHCARTGG GCNAARYTNGARGGNTCNCCNAAYGARGTNGAYAAYAGYGTNYTNCCNGCNTGYGCNGCN CCNGTN---AAYGCNGARGCNCCNMGNTAYCCNAGYTCNTCNCAYCAYTCNMGNGAYTGG GAYAARYTNGCNGCNGARGTNACNGARGARGARAARAAYGARAARYTNGARGGNGAYGCN GCNYTNAAYCARTTYTTYCARAARATHTAYGCNGAYGCNTCNGAYGAYACNAARAARGCN ATGATGAARTCNTTYTCNGARTCNGGNGGNACNGTNYTNAGYACNAAYTGGGAYGARGTN GGNAAYAARAARGTNGAYGTNAARCCNCCNGAYGGNATGGARTAYAARAARTGGGAR--- ------------------------------------------------------------ ---------------GCNTCNACNGCNTCNGCNAARAARGCNAARCCNGARCCNAARCCN GCNACNGTNAARGGNMGNGGNMGNCCNCCNYTNTCNGCNGARGARAARGCNAARMGNGCN GCNAGYAARAARCCNTCN---GGNMGNGGNMGNGGNMGNCCNAARGGNTCNACNAARGCN TCNAARAGYAARAARGTNATHAAYGAYMGNGTNAAYGCNGGNTAYATHAARMGNAARGAR YTNTTYGTNACNTCNAARGTNCCNGGNGTNMGNATGGCNACNGGNGAYGTNATGAAYTCN GGNYTNCARTCNYTNGARAARATGAARYTNCCNCAYYTNGAYATGYTNYTNYTNCAYAGY GCNTGGAARGGNAAYYTNAAYGTNGTNGAYGTNTGGMGNGCNYTNGARTCNATGTGYATH GAYGGNYTNGTNTCNAGYATHGGNGTNTCNAAYTTYACNGCNGARCARATHGAYAARGTN YTNAARATHCARAARGTNCCNYTNTCNAAYGTNCARYTNGARGCNCAYATHTAYTAYCAR CARAARAARATHAARCARYTNTGYGAYAARAAYAAYGTNGTNATHTCNGCNTAYGCNCCN YTNGGNTCNCCNGCNMGNCCNAGYCARCAYGTNACNGGNACNTCNTCNYTNYTNGARGAY CCNGTNATHYTNCARATGTGYGARMGNTAYAARAARACNCCNGCNCARGTNATGYTNAAY TTYYTNGTNAARAAYGGNATGGTNGTNYTNCCNAARAGYTCNAGYAARGARMGNYTNCAR GAYAAYYTNCAYTGYYTNGAYTGGTCNYTNAGYGARAGYGAYTTYAARGCNATHCARGGN YTNGAYMGNGGNATHAARYTNTTYGARTTYATGTAYGTNAARGGNCAYCCNGAYTTYTTY CAYGGNAGYGARTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ AARYTNYTNAGYGTNAARACNCCNATHGTNGARGCNGAYAARATHMGNACNYTNGCNTGY AARGCNYTNGCNGGNATGTCNMGNTCNGARACNATHMGNCARATHATHGGNAARMGNCCN CCNYTNAAYAAYGGNCARYTNCARTCNYTNGTNAARGARCCNGTNYTNTCNGAYAARMGN ACNGTNCAYYTNYTNTTYTGYAARTAYGCNTCNACNYTNYTNGARAARATHGCNGGNAAR GAYACNACNGTNTTYGGNGCNACNACNYTNGARGARATHMGNMGNGCNGGNGTNGTNGCN CARACNAARATHGTNTAYCARGAYMGNGARYTNYTNCARYTNATHCAYGARCAYYTNACN TCNAARGGNYTNCAYGAYACNGCNTCNGCNYTNCARAARGARGCNAGYYTNCCNAARTGY TCNACNCCNCCNCCNCAYCCNTTYACNTGYACNCCNAARGCNMGNMGNCARYTNAGYCAR CCNAAYGGNCCNAGYATHTCNTCNCARAGYCCNACNTCNAGYGGNATHCCNGCNTCNCAR CAYCAYACNGGNCCNATHAARTTYAGYYTNAGYMGNACNCCNGCNACNAGYAAYACNCCN CARACNAGYYTNCCNAARTCNACNAARMGNMGNTTYGARGGNATHATHCCNCCNGGNCCN CARCARMGNTCNAGYGGNAGYGARTAYGARGTNTCNYTNGAYAARATHGTNACNGARTAY YTNMGNAARCARCAYGCNYTNTGYCCNCARCCNATHTCNACNTGYCCNACNATGTCNYTN TTYYTNCCNCAYCARTGYCCNGARCCNYTNGGNAARGAYAGYGCNTCNGTNTCNATHTCN AGYMGNYTNTTYGAYMGNCARATGMGNCCNCCNCAYGGNGGNCCNAAYGGNCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATHGCNCCNAARACNTCNCCN TCNCCNAARTTYGTNCCNTAYGTNCCNYTNCCNMGNATGAGYCCNAARMGNAARGARYTN AAYMGNCARGTNMGNCAYATHYTNCCNAARTCNTTYGTNTTYGARTCNAARTCNCCNTCN CCNACNAARACNACNGCNYTNAAYYTNAARAARAARGCNACNYTNYTNTGYCARAARAGY CCNGTNAARATHYTNCCNMGNCCNGCNAGYATHCCNGTNGCNGAYATHGGNATGAARACN MGNAGYMGNTCNTCNATGYTNACNMGNTCNCARMGNGGNATHTCNAARCCNAARATH--- ------AARGARGARCCNTCNCAYAARGARYTNAARMGNGTNAARAARACNGARGARGAY TAYGARAGYGCNAARGARACNGARAGYGARGCNAGY------------------------ ---GARTTYGARGARTCNGGNYTNTCNCARGARGARGAYGAR------GAYMGNACNAAR YTNGAYGAYYTNATGGCNGCNAGYACNACNATHMGNTTYGGNTCNAARCARYTNGCNACN ACNGAYGAYGAYGTNAARACNAARGCNGARMGNAARAARGCNATGTCNYTNTCNYTNYTN CARCCNGAYYTNGTNCARAAYGAYCCNAARAARGAYGAYMGNGAYACNGCNTTYGCNCAR CARTAYTTYAAYCARGTNAARAARACNYTNTCNTCNGAYCCNGARMGNTTYTAYAARTTY YTNTCNYTNYTNAARGAYYTNAAYAARGAYCAYACNAGYCCNGTNGARYTNTAYYTNGAY ATGGTNYTNYTNYTNTCNGAYCAYCARCARYTNGTNGAYGAYTTYGCNGGNTTYYTNYTN TCNTTYCARGCNGTNGARTGYCARTGYTTYTCNACNACNTTYCARTAYACNCARATHMGN CARTTYYTNMGNCARGTNGARGTNCAYTGYGGNTCNTCNACNACN---ACNTAYMGNAAR GTNYTNAARGCNYTNTCNACNTGGAGYAGYATGTGYCARGARGGNAARYTNGARGGNAGY YTNMGNGARAARATGYTNGCNATHYTNAARAAYGTNCCNGGNGTNYTNGAYAGYYTNATH GGNTAYTTYYTNGAYAGYGCNGTNTCNGAYTGYCAYGCNATGGAYTTYGARGAYGTNTGY YTNGAYGARGARATGGARAARGGNGARGGN------GAYTTYGARAAYATHGTNYTNCCN GAYGARCCNGARGAYTAYAAYACNAARACNTGYTCNTGYCARTGYCAYAGYAGYAAYCCN CARGAYGAYMGNTAYCARMGNMGNATHAARCAYTGYGTNTCNTGYAGYYTNCARGTNTAY GAYGGNCARCCNGTNYTNAARYTNTCNMGNTAYGARTCNMGNCCNATGTCNATHGTNTAY TCN---------TCNGARGARAARGARAARTGYGCNCARGCNAARATHGARGCNGCNCAR ATHGTNYTNGCNAARGCNAARGTNCAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNGCNMGNAAYGAYYTNGARGARGTNMGNAAR YTNYTNGGNGARAAYGTNAGYCCNGAYGTNACNAAYGARGAYGGNYTNACNGCNYTNCAY CARTGYTGYATHGAYGAYAAYGARGARATGYTNAARYTNYTNYTNGARTTYGGNGCNAAY GTNAAYGCNTGYGAYAGYGARATGTGGACNCCNYTNCAYGCNGCNGCNACNTGYGGNCAY GTNACNYTNTGYAARCAYYTNATHGAYMGNGGNGCNGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AARACNTAYCCNTGGCARTGY ATGGARTGYAARACNTGYGTNCARTGYATGGAYCCNTAYGAYGARGAYAARATGATGTTY TGYGAYMGNTGYGAYMGNGGNTAYCAYACNTTYTGYATHGGNYTNGARGCNYTNCCNACN GGNCAYTGGGARTGYMGNAGYTGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARGTNATHTGYGTNGGNGGNGGNTAYGAYYTNGGNTAYATHGARTCNYTN GGNTGYTCNGGNATHACNAAYATHAARGAYTTYGTNAGYGGNGGNGGNTCNTAYYTNGGN ATHTGYGCNGGNGCNTAYTTYGCNTCNGAYTTYATHGARTTYGAYGTNAAYGGNCCNYTN GARGTNGTNGGNGARMGNAAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATGGCNAARMGNGGNCCNCARTCNGARYTNAAYGAYMGNAAYTGGGAYGAYGAR GARGARGTNGARGARGCNGGNGTNTTYAARCARGCNTCNTCNGAYGCNATGCARAGYMGN GTNATHAARAARGCNAARMGNMGNGGNGGNGGNGARGARGGNGGNAARTCNGGNGCNTTY GGNGGNTTYGGNGGNYTN---------TCNAARGCNACNCCNACNGCNTCNTCNCCNATG ATGGGNYTNGGNGGNAARACNTCNACNGARAAYAARCCNTTYAGYMGNGGNGCNGCNACN TCNGAYAAYAAYGTNGARTCNGCNACNAGYAARAAYGAYTCNACNACNAARGAYAAYTCN TCNTAYYTNCAYTCNYTNAARGCNYTNAAYGARAGYGTNYTNGCNTGGATHAARCARCAY GTNGAYAARAAYCCNTAYATHATHYTNACNCCNATHTTYAARGAYTAYGARAARTAYGTN GCNAGYYTNGARGCNAARAARACNACNGCNTCNACNAAYGAYTTYAAYTTYAAYAARGAY GGNAARAARGAYAARAAYACNGARATGTCNGCNAARGGNCCNACNTTYACNTTYGGNTCN GCNTCNGCNTCNAAYGGN---GAYGGNTTYAARTTYTCNACNGCNATHGCNACNACNACN AAYTCN---GGNTTYAGYTTYGGNAARACNGCNGCNCCNTCNATHTCNTCNGGNTTYTCN TTYGGNAGYAGYTCNGCNTCNAARTCNYTNGCNGCNGCNACNGCN---------ACNACN ACNGCNGCNTCNACNGGNTTYTCNTTYGGNAGYAGYAGYAGYAGYACNGCNTCNACNACN GCNACN---------------------------GCN------------GCNCCNTTYGGN ------------------GCNTCNGGNTTYTCNTTYGGNGCNYTNGCNGCNGCNAARGTN GCNTCNGAYAARGCNCARGCNGGNAAYCCNTCNGARGGNGGNGGNGAYGAYGAYGARTAY GTNCCNCCNAARCCNGARGTNAARGARATHAARGARGARGGNTCNGTNTAYTCNAARMGN TGYAARYTNTTYTAYCARAARGARGGNGGNTGGATHGARMGNGGNGTNGGNAAYGTNCAY GTNAARCCNYTNGAYGARCCNAARACNCARYTNYTNATHMGNGCNGAYACNAAYYTNGGN AAYATHYTNYTNAAYATHAAYYTNACNTCNGCNYTNCCNGTNTCNMGNCARGGNAARAAY AAYGTNYTNYTNGTNTGYGTNCCNAAYCCNCCNYTN------------AARGARGGNTCN ACNGAYCARACNCCNATHTCNATGYTNATHMGNGTNAARACNGCNGCNGARGCNGAYGAR YTNYTNGCNAARYTNGARGARMGNAARGCNYTNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGMGNYTNGARGGNAARAARACNCCNMGNTCNCCNMGNCARGGNCCNYTN CAYCARACNTCNAARGGNGCNGGNTGGGAYGARAAYCCNCCNCARAAYMGNAGYMGNCCN GARGGNGARAGYATHGCNCARAARAAYAGYGCNGAYTCNATGGGNGAYATHYTNGTNCAR AAYAAYGTNCCNCCNCCNCARMGNAARGARGGNAARGTNYTNAARCAYYTNCARCARTCN GAYATGTCNMGNCAYATHCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATHGCNGARTTYTTYGGNGCNACNGAR GGNGTNACNYTNYTNYTNAAYATHGCNAAYAARCCNGGNGCNATHGGNMGNYTNTCNCCN TTYYTNGCNYTNGAYCCNGAYCCNAARGCNYTNGTNAARTTYGAYTAYGGNACNGCNCAR CCNATHMGNGAYAARAAYGGNCAYTGYGTNAARGTNAARGTNGGNGARCCNGGNYTNTTY ATHAGYCARGTNCCNGARAGYATGATH--------------------------------- ------------------------------------------------------------ ------------------------CARAGYTTYACNCARATHATHATHTCNCCNCAYCAR GCNGARGTNYTNACNMGNGARGAYMGNTTYYTNTAYYTNTGGGGNACNTCNGGNTCNGGN AARACNYTNYTNYTNACNYTNAARGGNMGNAARTGGYTNMGNCARTGGMGNACNGTNATH ATHYTNAAYACNMGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CARGAYGCNYTNMGNYTN GCNGARAAYAARATGGARGARATHYTNCAYACNGARTGGCCNYTNCAYCCNGCNGGNCAR ATHYTNCAYATHATGGAYATHAAYGGNGAYACNGTNTGYGGNGGNGAYCCNCARTTYTGY GCNGTNTGGTCNAGYCCNGARTAYTTYGAYAARATHGTNATHAGYCAYAARATGGTNAAR CCNGTNAARGGNAAYGTNAARATHGCNTCNCCNTTYACNCCNATGGCNCCNTAYGAYGCN ATGAAYACNCCNGAYYTNAARAARGCNGTNACNAARGTNGGNGTNMGNCCNATGGGNAAR AARMGNATGMGNGAYYTNYTNAARCAYATHTAYACNGARACNCAYCARTAYGARACNGAY TCNGGNGAYGGNGAYACNCCNYTNAARCCNCCNAAYCCNAAYGTNCCN------------ ---TTYAARGARGCNCCN------------AARTAYAARGARGTNTCNAARAARCARYTN TTYGCNAARTCNTCNTCNGARACNMGNATHTGYCCNAAYGCNCARAGYACNAGYAARGGN ACNGGNATGTCNTCNAAYGAYGGNAARTGYGGN--------------------------- ------------------AARATGGARACNYTNGAYAARACNAARGCNTGGGTNGAYAAR ATHCARGGNTTYCCNAAYCCNYTNTCNTCN------------------------------ GAYGARCARGTNGAYMGNGARGARGAYGTNYTNAGYTCNCARGAYTCNAGYTTYAGYGAY GGNCCNGAYGTNCCNGARGARAGYATHYTNCARGTNYTNCCNGAYGARGARGARAAYGAR GCNCCNTGYACNCARYTNTCNCARACNAGYYTNGGNGTNATGAAYGAYMGNYTNATGGCN TTYYTNMGNGAYAAYCCNAARATHTAYGARCARATHYTNATGTAYGARGCNYTNGARYTN GAYGTNYTNAARAARAARATHGCNGAYGCNGGNATHMGNGTNGGNTTYTCNMGNYTNCAR GAYTTYYTNGAYGARMGNTGYGTNACNTTYTCNATGAARAAYATHGGNAAYMGNAAYAAY MGNCARCARCARAARMGNAARAARGGNAAYTCNCCNACNAARMGNAARAARACN------ ---------------------------------------------GAYGGNTGGTTYGGN ACNYTNAARGAYAAYATHYTNGGNGARYTNAAYTCNTCNYTNATGGCNGTNYTNMGNACN CARCARGARGAYCAYYTNAARTCNTGYGARGAYGTNCARGCNGARAARGGNGCNYTNCAR AARGARGTNAAYCARYTNACNGARCARATGAAYAGYYTNGARCAYAGYTCNAARCARAAR TGYACNYTNGTNAARAAYYTNACNGAYTCNYTNGTNGCNCARAARAARAARGTNGARATG GCNAARCAYTTYTAYCAYTGGAARGCNGAYCAYTAYGAYAARCARMGNGARATGTTYACN GARAARYTNGCNGCNCARCAYCAYGARMGNAARYTNAAYYTNMGNGTNYTNAARGCNTGG TAYGGNACNATHCARACNMGNTGGMGNTCNMGNACNGARMGNAARAGYCARACNCARGCN AARGARATGTGYATGAGYYTNAGYAGYGAYTAYGARGTNAARGTNGGNACNYTNAAYGAR AARGTNGCNGCNYTNGARAARAARGTNTCNYTNYTNCARGCNGARMGNGARATGTAYTCN GARCARGTNAARAARGCNTTYATGMGNGGNATGTGYGCNYTNAAYATGGARACNATGTCN GTNTTYAGYCARGAYACNGAYGARTCNYTNATHGAYATHATHCARGARGTN------TCN ACNTTYGAYACNAAYACNYTNGTNACNAGYYTNGARGARATGGAYAGYCAR--------- ---------------------CCNAARTCNATHCCNAAYACNGTNGARAARAGYTCNTCN CARTCNCAYTCNTCNTCNYTNCCNATGCARAAYYTNATGCARCARCAYTCNCCNATHGTN TGYGGNGCNGCNCCN------------------AARCCNAARGCNACNAARAGYAARCCN AARTCNGCNAAR---TAYCARGGNAAYAAYAAYAARGTNGTNTCNTCNTCN--------- ------------------CARGTNYTNGCNCCNCCNATGGCNTCNGTNGTNGTNGARMGN CAYCCNCCNGTNAAYAARCARACNATGGGNAARGCNACNGCNATGMGNTAYCCNAAR--- ------------------------------AAYGAYGARMGNAAYMGNCARGTNACNTTY ACNAARMGNAARTTYGGNYTNATGAARAARGCNTAYGARYTNAGYGTNYTNTGYGAYTGY GARATHGCNYTNATHATHTTYACNAGYAAYAAYAARYTNTAYCARTAYGCNAGYTCNGAY ATGGAYAARGTNYTNYTNAARTAYACNGARTAYAAYGAYTCNGTNGTNAGYCARACNAAY AARGAYATHATGGAYATGYTNAAYAARAARGARAGYAARGGNGGNGAYTAYGAYGGNGAY GAYGAYGARTTYCCNYTNTCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGAGYTCN GAYACNTGYTTYAARTGYGGNGGNMGNGGNCAYTTYGCNMGNTAYTGY------GGNGTN GGNGGNGAYGGNCCN---GGNMGN---------------------------------GGN TTYTCNGGNCARAARTGYTAYAARTGYAAYMGNATGGGNCAYTTYGCNMGNGARTGYACN CARGAYCARGARMGNTGYTAYAARTGYAAYGGNYTNGGNCAYATHGCNAARGAYTGYGAR AARCARATHTCN---ACNGGNGCNTGYTAYAAYTGYGGNAGYAGYGARCAYYTNCARMGN GAYTGYCCNGAYGCNATHGTNAARTCNTGYTAYMGNTGYGGNGAYTCNGGNCAYYTNGCN AARGARTGYCCNGCNGAYATHCCNGGNAARCCNTTYGCN------------GAYGAYMGN AARTGYTAYACNTGYGGNGGNATHGGNCAYYTNGCNAARGAYTGYCCN------------ TCNCCNMGNAARGARTGYTAYMGNTGYAAYCARACNGGNCAYYTNCARAARGAYTGYCCN AAYGAR---ACN---GAYACNYTNTGYTAYAAYTGYAAYAARGCNGGNCAYATHGCNMGN GAYTGY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNCAYYTNATHGTNACN GCNGAYGAYTTYGGNTTYAGYAARGARMGNAAYCARGGNGTNATGGARGTNTTYCAYAAR TCNGGNGTNAARAGYGCNTCNYTNYTNYTNAAYTGYACNGGNACNACNGAYGCNGCNCAR YTNYTNAARACNCAYGARYTNGTNTCNGGNYTNCAYYTNAAYYTNACNGARGGNCAYGCN YTNAGYAARACNGCNCAYTCNATGYTNACNGAYTCNACNGGNAARTTYTGGGGNAARTTY GARYTNMGNAARYTNYTNGARACNGGNMGNATHTCNCAYYTNGARATHAARGAYGARATH GARTGYCARATHAARYTNTTYAARGAYYTNGTNGGNAARCAYCCNGTNTAYGTNGAYGGN CAYCARCAYATHCAYGTNCAYCCNGCNGTNGCNGARATHTTYGCNTCNACNYTNCAYACN TAYGGNATHCARGCNACNMGNTTYCCNGTNGARYTNTCNYTNGARAGYAARCARTGGATH AAYCCNMGNGTNGTNCCNTTYTAYAAYAARGTNATGGARGAYGCNGARAARTGYAARTCN ATHTTYGARTCNAAYTGYATHMGNTAYACNGAYGCNTTYGTNGGNYTNTCNACNATGGGN GCNGAYATGACNACNACNMGNYTNCARTCNAGYATHYTNGARGGNTTYCARAAYGCNGAR AARMGNTGYGARGARTCNMGNACNTCNTTYGTNACNTGYGARYTNATGTGYCAYCCNGGN TAYGCNACNGGNAARGAYTCNGGNGGNTTYGAYGGNMGNTCNGAYGARTTYGGNTGYTCN AAYGAYMGNGARCAYGARGTNCAYGTNYTNACNTCNAARGARATGYTNGARTTYTAYGAR AARAAYAAYATHAARYTNGTNTCNCAYGARGTNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATHGTNGCNCAY MGNYTNMGNCCNTTYGCN---YTNGGNYTNTAYGCNAARGCNGGNAARTCNATHCAYACN ACNCCNMGNAARTAYGGNGARGCNYTNTAYMGNGARAARATG------TTYGAYTAYAAR GARCCNAARTAYATHCAYCAYGCNGGNACNGCNTTYAGYGCNTTYATGTGGTAYTGGATH YTNTAYCAYTGYTAYTTYGARTTYGGNCAYYTNGTN------------------------ ---------------------ATGCCNGGNGARGARCARGTNGTNTTYYTNAAYAARYTN GGNGARATHCCNGTNYTNAAYGAYAGYTGGTTYGCNGCNGCNGAYTAYTAYTCNMGNGTN AARGAYTAYAAYGCNYTNATGMGNATGACNYTNTCNGTNGCNGARTCNGGNGTNAARGTN GCNGGNCAYYTNTCNACNCCNGTNATHAAYMGNTGYCARCCNCARATHAAYAAYYTNAAY GAYTTYGCNTGYAARACNYTNGAYGAYYTNGARACNAARTAYCCNGCNATHAARCARCCN ACNGARCARTGGAARGARACNTGYGCNGAYTTYGTNGARCCNGTNGTNGGNMGNGTNAAR CCNGTNATHTCNCARGTNCARGGNATHGTNGAYAAYGGNAARCARMGNATHAAYAGYATH AARAGYGCNAGYACNAAYATGATHGARGGNGCNAARACNMGNGGNGTNGGNACNGTNACN CAYGTNGTNAAYACNACNTTYGARACNGCNCCNGGNMGNTTYGTNACNMGNACNGTNGAY AGYGCNYTNGAYGTNGCNGAYAAYYTNGTNGAYAARTAYYTNCCNGARGARAARGAR--- ------GARACNGAYGARCARCARGAYGARAARGARTCNACNACNAGYGCNCAR------ ---------TCNGARGTNGARAAYATGGARGARATGGAYCCNACNCCNMGNMGNGTNYTN GTNCAYGCNGGNTGYGTNACNGAYAARATHMGNAARMGNATGTAYMGNMGNGCNATGAAR GAYATHACNTAYGCNMGNGCNMGNACNTCNGCNGCNYTNMGNAARATGACNAGYACNGTN GARYTNATGGAYYTNGCNAARAARAAYYTNAAYACNACNAARGARAARGTNGAYCARYTN TGGACNGAYATHGTNAARGAYACNGAYGCNGCNGAYGAYAAR------------ACNGTN TAYGTNGGNACNGTNGARGAYMGNATHGTNGCNYTNGGNMGNATHYTNGCNMGNCARGTN MGNTCNGGNGTNACNGCNTTYGARAARGCNTAYTCNGARYTNGGNGARTTYAGYAARAAY CCNATHTCNAARTCNAARGARTAYAARGAYYTNATHACNACNTTYYTNACNGTNGARTCN ATHAARAAYATGACNTCNCARAAYYTNCARMGNGCNAARGARTCNYTNAARTAYYTNCAR GAYMGNYTNAARAAYATGATHCCNTCNYTN---------AGYTGGGTNACNGTNGAYATH AAYATGGARGAYATHCCNATHAGYGARACNGAYYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNATGTGGTAYCAYATGGARMGNACNCARGAR ACNTAYMGNYTNTCNGAYCARYTNATHMGNGCNATHGGNAARGGNAARYTNCAYGAYMGN GARGARGAYATHAAYTCNYTNATHAAYAARGGNGCNGAYGTNAAYMGNMGNCAYGGNACN YTNYTNCCNYTNCARTAYGCNTGYTGYYTNGGNGAYTGGCAYGTNYTNGAYYTNYTNATH CARCAYGGNGCNAARGTNAAYGARCCNGAYGGNTAYAAYMGNACNGCNYTNCAYTAYGCN GCNGARCARGAYGARAAYTGYGTNMGNATHYTNYTNGARAAYGGNGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARACNGCNTTYGTN ACNGGNGCNGCNAARGGNYTNGGNAARGCNTAYGTNGARAARTTYYTNGARGARGGNGCN AGYGTNTTYTTYGGNGAYATHGAYGGNGARYTNGGNAARACNACNGARCARGARYTNCAR GGNAARCAYGGNAARGAYMGNGTNGTNTTYTTYCCNTTYGAYGTNACNAAYGGNGARCAR TTYAARGARGCNGTNGAYAARGCNGTNTCNCAYTTYGGNAAYATHGAYGTNTTYATHAAY AAYGCNGGNATHYTNAAYGARGGNGTNTGGGARAARATGATHGCNATHAAYTTYACNGCN GTNGTNMGNGGNAGYAAYYTNGCNATGGARCAYATGMGNAARGAYAARGGNGGNAARGGN GGNMGNYTNATHAAYATHAGYTCNATHATHGGNYTNTCNACNCAYGARTCNATGCCNGTN TAYTGYGGNACNAARCAYGCNGTNMGNTCNTAYACNMGNTCNYTNACNACNATHCCNGGN YTNGARTCNGAYATGGGNATGGARATHGCNATHYTNTGYCCNGAYGCNGCNAAYACNGAY YTNATGACNAARYTNGAYGAYGARAARYTN------------GGNTAYAAYGAYGARATH AARGARGTNATHGAYGARMGNATGATHTCNGTNTCNACNGTNGTNGAYGGNYTNTTYTCN YTNYTNAARMGNGARGAYTCNATHAAYGGNGCNATHYTNYTNGTNGTNAARGAYGGNAAR AGYTTYCARGARATGGARCCNGTNGAYYTNGGNAGYGARTGGCCNGTNCCNGCNAAYGGN AARGTNTGYAARACNAARGCNGARTGYCARCCNAAYGARTGYTGYCARATHYTNAGYGAR YTNATGATHGTNAGYAARMGNGAYATH---YTNCCNYTNCCNAARGTNAARGCNGGNAAR ACN------GGNACNTGYGARCCNTAYAARYTNGARGGNCARACNTGYGAYTCNTTYGGN MGNATGAAYGGNTAYTGYGAYTGYGARCCNGGNACNAARTGYAARGGNTCNATGATH--- ---------AARTCNACNMGNTCNMGNMGNGAYATGGTNATGCCNCCNTCNGGNTAYAAR TAYGARACNAARTGY------GTNGAYTAYCAYGARATGGGNTTYGTNTAYAAYMGNGCN ACNGGNACNGAYGTNGAYMGNGTNTAYGARTTYGGNTGYTAYYTNATGGCNCCNCARCAY TCNYTNGTNYTNTTYCCNTCNACNGCNCAYTTYYTNGAYYTNAARYTNTCNGTNATGAAY AARGCNGGNYTNACNATHGGNYTNCARGTNTAYYTNCARTAYYTNYTNMGNCCNAAYGAR YTNTCNCARATGTAYMGNAARTAYAAYAARGAYTAYAARAARATHATHTAYATHATGGCN GARAGYACNGTNAARAAYATGGCNATHGARTTYACNYTNGAYCAYTAYMGNYTNAAYMGN TCNATGGTNGARGCNAGYGTNTTYCAYMGNYTNAARMGNGTNYTNTCNGGNGAYTGYTGY AAYACNTCNTCNCAYCAYATHCARATGATHAAYCARACNACNGCNTGYAAYGCN------ ------AAYGCNTCNACNTGYGAYCCNGGNTTYCAYGTNGAYYTNGCNTTYTTYCARATG GGNAGYATHACNATHCCNAARGAYATHACNAGYCAYTAYYTNAARCARATHATHYTNMGN YTNGARACNGARMGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TCNTGGYTNGTNGGNGTNGCNTCNTGYCCNATHTAYTAYAARTGGGAR GAYTTYGGNACNYTNTAYTGGCCNMGNTGGGTNAARACNGGNTCNTGYTCNMGNCCNGTN CAYGGNATGYTNTCNAARYTNTCNAAYGCNTCNTCNATHTTYTCNAARCCNCCNGCNTCN ---TCNTCNCCNTCNTGYTCNTGGCCNTCNGGNATGMGNTGYGTNCCNGGNAARGARAAR AARYTNMGNYTNYTNMGNTGGACNTGYAAR------------------------------ TCNTCN---YTNGGNGTNYTNGCNYTNGTNYTNCCNGGNGTNAGYGCNYTNAGYGAYMGN GTNCCNATHATHGCNTCNTCNGCNGTNGCNYTNTTYATGTTYYTNATHYTNATHGTNGTN ATHGTNTTYGCNAGYTGYTTYTCNCARAAYTGGATHMGNTCNAGYATGAARMGNGARGGN AARGTNAARATGCCNMGNTCNTAYTTYGAYAARAARMGNGARGCNAARMGNMGNYTNATG GCNGARTCNGTNGCNCCNGCNCCNGCNCCNATGGTNAAYGGNTCNATGCCNCCNYTNGCN ATGCCNCCNYTNGAYAAR---------GARACNYTNGTNCARGGNTGGAAYCAR------ ---AAYACNMGNAARATHTAYGARGARMGNGGNAARACNATGGARYTNGGNGAYGARATH GAYGARGARTTYCAYATHGARACNACNATHGTNGAYAAYGARGTNYTNGAYGTNGGNCCN TAYAARAAYYTNGGNTCN---ACNAGYGCNAARCCNGTNGARGGNAAYGTNTAYGCNAAY CCNTAYYTNTAYAGYAAYAAYGAYMGNGTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TTYAAR GGNAARGTNTAYGTNGTNGGNMGNGAYGAYAGYYTNGGNAARGARATGAARGAYGCNGGN ATHTCNTAYACNGGNCCNGGNCCNGAYCCNGTNCARACN---GAYYTNYTNGCNCAYYTN GCNACNGARYTNGAYCCNGARGTNAAYTGYGTNGTNGTNGGNTTYGAYCCNCAYATHAGY TTYYTNAARATHYTNAARGCNGCNAGYTAYYTNAARAARCCNGAYTGYYTNTTYATHGGN ACNAAYGARGAYCCNTGYYTNCCNACNAARGGNCCNATHACNYTNCCNGGNACNGGNACN ATGGTNGCNGCNGTNAARGCNGCNAGYGARMGNGTNCCNTTYATHGTNGGNAARCCNGAR GTNTGYATGTTYGARATGYTNCARGARYTNCAYGGNYTNGAYCCNTCNMGNTGYYTNATG ACNGGNGAYMGNYTNGARTCNGAYATHGTNTTYGCNAARAARTGYGGNATGAARTCNTTY YTNGTNYTNACNGGNAAYGAYTGYGTNGAYGAYATHAARAARMGNGGNATH------ACN CCNGAYTTYTAYGCNGAYTGYYTNGGNACNYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNGARGAYTAYGAYCCNGCNGARCCNACNGAR GAYGAYGAY------GAYGGNAARGAYAARGAR---TCNAGYYTNTAYTGYCAYGTNTGY TCNGTNTCNGTNTAYGAYGAYGAYAGYTTYCARMGNCAYYTNAAYGGNYTNAARCAYAAR TCNMGNATGGARGAYATHGCNACNGTNCAYACNGTNMGNTCNTCNCARYTNAAYTTYMGN YTNAARGCNGARGARCAYYTNMGNAAYATHGARMGNMGNGARGGNMGNGAYCCNGAYTAY TTYTGYAARATHTGYAAYAAYGAYYTNGCNATHCCNTGGGARAARCAYMGNTAYTCNAAY ATHCAYAARCARMGNYTNYTNCARGTNMGNAARGGNTGYGGNTGGTGYAARGTNCAYGAY TTYACNAAYTTYACNGARGTNYTNGARCAYMGNGAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TAYGAYCCNGARACNMGNGARYTN AARAARATHTGGACNTGYAARATGCCNGTNCAYGGNGCNYTNYTNGGNTAYMGNGARCAY YTNYTNACNYTNGGNGAYAARATHAAYCARYTNGGNGTNGAYMGNGCNGARACNGCNYTN YTNTGYGCNATHAGYATGACNAGYATHGAYTGYCCNAGYYTNGTNAARCCNGAYACNGTN TCNGARGTNCARAGYGTNYTNATHGARTCNYTNGARGCNTAYTCNGCNAARGGNCAYTCN GGNGGNMGNYTNCARACNYTNYTNGGNYTNATGCCNCARGTNMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GARCARGGNTTYYTNGAYTTYATHCAYGGNYTNAARYTNGCNGTNATG AARGARTTYGGNAGYATHTCNYTNAARGARCARYTNAGYYTNAAYAAYATHGTNTCNATH TTYGGNCAYATHMGNGARMGNGTNGARTGYGGNGTNGAYAARCCNACNATHTCNYTNTAY CCNTAYYTNATHMGNTGYGARCARGTNCCNGTNCCNGAYACNCARAAYGTNATHAAYCCN GARGAYGAYYTNTAYGARAARYTNATHAGYGARACNMGNGAYATHYTNGARAGYTAYGAY TTYCAYTCNGTNYTNAARTCNAGYATHGAYMGNGGNTTYAAYTGYATHATGGAYGCNYTN GCNGAYCAYTTYAARCARGTNACNGCNGGNGTNCAYGARCAYTCNAGYATHCAYGAYYTN TCNYTNGCNATGGCNAARYTNATHCCNGTNYTNAGYGCNYTNYTNCCNAARATHTGYGGN GAYGCNCCNAAYCCNTTYATGCARGARYTNYTNATGATGGARGARYTNAARCARYTNGCN GCNAAYGTNTAYGARGCNTTYAGYCARGAYCCNAGYAAYAARCCN--------------- ------------------------------------------------------------ ------GTNTGGGCNAARATHACNGCNGARATGAARGTNTCNTCNATGCARGTNGCNGAY TGGAARACNAARTGGAARTGYYTNMGNGAYACNTTYGTNAARAARMGNAARGAYATHATG GCNGAYTCNCARGTNGCNGTNGCNAARACNCAYTGGMGNTTYTAYGAYCAYATGTCNTTY YTNGAYAARACNGTNCCNMGNAGYGGNAGYGAYTAYCARCAYTAYACNATHATHAARGAR TAYGCNGARGGNGAYTCNATHGARGARGGNGARGTNAAYTCNTCNGGNAARCAYCCNGCN AAYGARTCNGGNCCNGGNTCNCCNAARMGNMGNMGNTTYAAYAAYCAYGTNGAYACNGAR TCNGGNGAYGAYYTNCARGAYGAYGAYGARGAYGARGARGAY---GAYGGNGAYGAYAGY TTYTTYATGTCNTGYGCNTAYMGNATGGAYMGNYTNCCNGAYMGNGTNCARTCNTAYYTN CARYTNCARATHTCNCARYTNTTYTTYAAYGCNGARAAYCCNGAYGTNTCNCCNGTNCCN ATHATGCCNYTNATGGCNCARTAYATHCARGTNGTNGARGAYGARAAYGAYGARACNATH GARATHCCNAGYGARYTNAAYGGNACNYTNYTNYTNACNACNYTNTCNGCNCARTTYCCN GGNGCNTGYGGNYTNAARTAYMGNAAYCCNGARACNMGNGCNTTYMGNGGNATHMGNYTN GTNGAYGGNGTNYTNCAYCCNGARAAYGGNTCNTGGGGNAAYCAYCARTAYGTNGCNGTN TTYCCNAARGARAAYAARMGNAARGGNGARGAYGGNTTYGAYAAYCCNGCNGCNAARACN AARMGNYTNGAYAGYCARAARTGYTCNGAYYTNATHGTNYTNGGNYTNCCNTGGAARAGY AAYGARGAYGAYYTNAARAARCAYTTYAAYCARTTYGGNGAYYTNGTNYTNGTNCARGTN AARMGNGAYATGAARTCNGGNCARTCNAARGGNTTYGGNTTYATHMGNTTYGTNAAYTAY GARGCNCARGTNAARTGYTGYGCNCARMGNCAYAAYATHGAYGGNMGNTGGTGYGAYGTN ACNATHCCNAAYTCNAAR------------GTNGGNAAYCARGGNTAYGAYTTYTCNCAR TAYTCNMGNGGNGGNTCNAGYMGNAAYTAYTAYAAYCARGAYMGNGAYGAYGGNAGYTAY ---CARGARGGNAAYAGYCCNATGATGAGYMGNAARGTNTTYATHGGNMGNGTNAGYGAR GAYYTNACNGTNGAYGAYYTNMGNAAYTAYTTYTCNAARTAYGGNGARGTNGTNGAYGTN TTYATHCCNAARCCNCAYMGNGCNTTYGCNTTYGTNACNTTYGCNGAYGCNGAYAGYGCN CARTCNYTNTGYGGNGARGAYCAYATHGTNAARGGNACNAGYGTNCAYGTNAGYAAYGCN GCNCCNAARACNTCNTAYGAYMGNGGNACNGAYMGNAARGGNTTYGGNGGNCAYATHGGN CARGGNGGNGGNTAYATGCARCCNTTYGGNGCNMGNGGNCCNGGNCCNGTNGGNGGNAAR ACNAAYGGNGCNGAYGGNGGNATGGCNGCNAAYAAYYTNGGNATGAAYYTNATHAAYTCN GCNATGYTNGCNGCNGCNCARGCNATGYTNGCNAAYCCNAAYAGYTGGAGYGGNATGAAY CARGGNACNCARGGNGGNACNGGNGGNAGYATGGGNGGNGGNGAYCAYCCNTCNACNATG GGNCARGTNTCNAGYCARGGNGGNTTYGGNAGYATGGCNGGNGCNACNGCNAGYGGNTCN GGNAGYGGNAAYTGGTGGGGNAAYGARGGNAGYTCNTCNTCNGGNGGNCAYTAYGGNGGN TGGGGNGGNTCNCAYGGNGGNMGNGGNGGNAGYGGNTGGAGY------GCNGCNTGYATG AGYYTNGAYAAYCCNGCNTTYMGNTCNTTYATHGGNTAYGCNGCNGTNGTNYTNGTNAAR ATGATGYTNATGAGYYTNYTNACNGCNTTYAAYMGNATHACNAARAARGTNTTYGCNTCN GARGARGAYACNGCNTAYTTY------AARGARACNMGNAARGGNGTNGTNYTN---AAY GAYCCNACNGTNGARMGNATHMGNMGNGCNCAYCARAAYGAYYTNGARAAYATHYTNGCN TTYGTNYTNYTNGGNGCNATHTAYTGYACNACNGGNCCNGTNYTNTCNACNGCNYTNYTN CAYTTYMGNGTNTTYACNGCNGCNMGNATHYTNCAYTCNATHGTNTAYYTNYTNCARGTN CCNCARCCNGCNMGNGCNACNGCNTTYTTYGTNGGNYTNGGNGTNAAYATGTCNYTNGCN TAYMGNATHATHYTNCARGCNGCNTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNGTNTAY CARGCNAARGAYGGNTGGTTYAGYGARAARTGYTAYAARGTNAAYCAYTCNACNAGYTCN TTYTCNTTYYTNGTNCCNTCNTTYYTNAAYTTYTCNTTYGGNGARGAYGAYGCNYTNGTN CARATHTGYATHGAYGAYTCNMGNGGNATHYTNTAYGCNMGNACNCARAAYGGNTCNATH CARGTNTTYGAYYTNGGNGARAAYAARAARGGNYTNAGYAARGTNGCNTAYCARTCNCAR GCNTCNATHYTNAAYACNGCNTCNGCNATHGCNMGNACNATHGARAARTCNAAYTTYAAR TCNATHATGCAYATHTCNGCNATHACNCAYMGNGARGCNGAYAGYGTNCAYYTNGTNGCN ATHACNGARACNGGNGTNMGNYTNTAYTTYTCNACNGTNCCNTCNAARCARTTYGAYCAY MGNCCNTGYACNYTNAGYYTNATHCAYGTNMGNYTNCCNCCNGGNTTYTCNGCNACNTCN ACNCCNGARMGNCCNACNAGYGTNCAYACNGCNTTYTAYAARAAYGAYACNTTYATGYTN GTNTCNTCNCARAGYCARGAYMGNGAYATHYTNTGGTGYATHAGYCCNGAYTCNTTYCCN TTYCARAARCARYTNATGGARGCNCAYACNATHATHTCNTGYGGNGGNAARACNTGGGCN ATHGARGARGTNCCNYTNAGYMGNTCNGTNAAYCCNCARTCNTCNTCNTCNYTNATGMGN CARGTNGCNGAYCCNCCNTGYGTNGTNACNCARCAYGCNTTYCCNCCNMGNMGNTTYGTN GTNYTNAGYACNCAYGGNGTNCAYATHGTNCARAARYTNMGNCCNGTNGARCARYTNAAR GCNYTNYTNYTNGARTGYGGNGGNCAYGAYTCNGARCARGTNAARGCNTTYTTYMGNYTN CAYAARYTNGAYCARGCNTGYGCNATHTGYYTNGTNYTNGCNTGYTCNMGNGCNGCNGCN GAYCARCARGTNTCNAAYGGNGCNMGNATGGCNTTYTTYATGTAYGGNGGNGARGCNCAR TGYAAYTTYGCNGGNATGMGNCCNATHGGNAGYCCNYTNCCNGGN--------------- ATGTAYAGYCCNGGN------ATGYTNCCNAAYAGYCCNYTNCCNAAYATGATGACNTCN ACNCCNGCNCCNGGNGCNATGGTNGGNTCNCCNGTNGGNGGNGGNAAYCCNAAYCCNYTN CARCARGARGTNATHTAYTCNGGNAARCAYAAYGGNATHTAYATHTTYTTYAGYMGNATH YTNMGNCCNTTYTGGGAYTAYCCNGTNACNACNGARTTYGTNCAYGAYTCNAARCARGGN AARGTNACNTAYYTNACNTCNAAYTTYACNGTNGARGARYTNMGNACNGCNYTNGARATG GTNMGNGAYYTNTCNGAYTTYGTNGAYTTYAAYTCNAARTTYGAYGTNGAYTCNCAYATH GAYATHATGAAYACNGGNMGNGGNMGNYTNGAYGGNACNATHGAYGARCARAGYMGNAAR MGNATGCAYATHGARGTNCARMGNATGGARAARATHTCNYTNCARCAYYTNCARGAYYTN YTNCAYMGNACNGARGARGTNYTNGGNYTNTGGTGYYTNYTNATHGAYCAYCARTTYCAY ATHYTNGCNGCNGCNATGGCNCCNGAYATHCARAAYCARYTNMGNAAYATGACNTTYAAR ACNYTNGTNACNAGYGGNAARGAYGTNTGYAGYACNYTNATHATHTGYYTNGTNAGYMGN TAYYTNAAYGAYAAYGCNACNATHGAYGCNATHAAYGAYMGNYTNMGNGARGTNTGYCCN ACNYTNTAYAGYACNGAYGAYGCNACNTGYTCNAARTCNAAYGARYTNYTNCARGCNGCN AARATGAAYCCNAAYAARYTNGARAARGARCARCARYTNCARGARGCNYTNCARYTNYTN AARGGNGTNTCNCARCCNYTNAAYYTNTCNGTNATHTGYTCNCARYTNGCNGGNGTNCAR TTYTAYYTNGGNATHGTNGARYTNGCNYTNAAYGARGCNGGNAARYTNGAYCCNCARGGN ATGGCNATHCAYTTYTAYAAYAAYGGNGARCCNCARGARGAYATHCARGGNATGCARGCN TAYATHGCNMGNATGGAYTGYTAYAARTGYATHACNGAYACNYTNTCNTAYYTNACNTCN GCNAGYACNAGYCARGCNCARGTNCCNAAYAAYCCNTTYATGTCNTCNTCNACNAAYCCN GTNGARCCNAAYMGNATGGAYCCNCARCARGCNGARTAYTTYAARGARGAYGTNTTYAAY ACNGCNYTNMGNTGYGAYGAYTCNYTNTTYCAYGCNTCNYTNTAYGARTGGYTNTTYAAY ACNAAYCARGCNGARAARYTNYTNGARATHAAYACNCCNTAYGTNGARCARTAYYTNMGN MGNAARGTNAAYYTNCARACNGAYAAYACNGGNGCNYTNGAYATGYTNTGGMGNTAYTAY GARAARGTNGARAAYTTYCCNGCNGCNACNMGNATHYTNTCNCARYTNGCNGARMGNCAY GGNACNAAYGTNAAYYTNACNCARMGNYTNGARTAYYTNTCNMGNGCNGTNGTNTGYGCN AARAGYTCNACNTCNMGNYTNGGNACNTCNGCNGGNGGNGARACNYTNCAYGARYTNGAR GARAARATGGARGTNGCNMGNYTNCARATGCARATHTAYMGNTGYYTNTGYAAYATGATG GCNACNCCNCCNGTNGARAGYGCNAARGCNMGNYTNGAYGCNGARYTNATGGAYATHACN ACNYTNTAYGARGARTTYGCNGAYCCNTTYGAYYTNCAYGARATGAARYTNGCNATHGTN CAYTGYGCNGGNYTNTAYGAYGCNGCNYTNATHGARGAYYTNTGGMGNAAYATHATHGAY AARGARATHGGNAGYACNTCNCARATGTCNGGNTCNGAYMGNATHAAYACNATHGCNGCN AARYTNTCNACNGTNGCNAARTCNTAYGTNAGYGCNGARMGNTAYTTYCCNGTNGCNYTN ATHYTNMGNCAYYTNGARGARAARTCNTGYGARYTNTCNYTNGAYYTNGARTGGGTNTTY AARATGATGYTNCAYGTNGGNGTNGCNCCNGCNMGNYTNYTNGARYTNTAYGAYMGNYTN TAYAARTCNAARGAYGTNATHTGGCARACNYTNGGNMGNCCNYTNCAYGTNYTNATGGCN YTNCAYGCNTTYATHGAYCAYYTNGCNMGNAAYCCN---ATHYTNYTNAARACNGTNAGY CCNCCNATGCARGTNTGGTGYYTNGAYYTNGTNGCNTCNTAYYTNGTNGAYYTNGGNGCN YTNGGNACNTCNACNMGNGAYGTNGCNCCNYTNATGACNGGNTAYAARGCNACNCARGCN AARYTNGARMGNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATHAARGAYTTYAAYGTNCCNTTYACNCAYGCNAARGGNMGNGCNAARGTNMGNGARGTN TTYATGAARAAYAARCAYGTNACNGAYATHMGNGTNATHGAYATGYTNGTNATHAARGGN CARATGGARYTNGTNGARACNGCNAAYATHTGGAARCARMGNCAYCAYATHATGGCNTAY TTYAARGAYACNGTNAAYCCNAARCCNACNGAYTTYYTNAGYAARTTYTAYGARGGNCAR GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYAAYYTNMGNMGNAARATGAAYTCN GGNGAYAAYATHTAYMGNMGNATGTCNGGNCARCCNYTNTAY------AGYCAYGTNGAY CARGARYTNGAYCAYAARGTNAARMGNGTNTCNGAYAARTTYTCNGARACNGTNAAYATG GTNGCNAAYGARCCNTCNYTNGCNTTYTTYMGNATHCARGARCAYGTNMGNAARACNYTN CCNCARYTNGTNGARACNAARCAYGARGTNGARGAYGTNCARTCNAARGTNCARGGNACN TGYTTYGAYGCNGAYTAYGCNGTNAAYGCNGTNAARGCNATGCARAGYAGYGCNATHCAY TTYCARAAYATHCARGAYYTNYTNAARAAYGCNATGTTYATGAARCARCARATHGCNTAY GARGAYAAYAARMGNAARCARGGNMGNAGYAGYCCNATGGCNGGNGARMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYGARGTNGTNMGNACN YTNATHGARGCNCAYCARAARTAYGTNACNCARTAYTTYAARGAYATHCCNAARGARGAR YTNGARAARCARCARMGNGAYCAYTAYGARTCNTGYGTNYTNMGNAARGARATHTTYGGN CAYATHMGNMGNATHCCNGAYCAYGARTAYGARCARYTNTAYGGNGCNACNGGNATHGAY GCNGAYAAYMGNGCNAARMGNATGCAYGAYTAYGCNAARGCNATGGARGARACNATHCAR YTNATGGTNTGYTTYGCNYTNGCNATHCCNGGNTTYTCNGARYTNCCNACNAAYGCNAAR YTNCAYYTNATHAARTTYTCNMGNCARGARTTYGCNYTNYTNAAYYTNGTNAARTAYGTN AAYYTNGARYTNAARGTNTAYMGNGGNGTNGARGAYGAYTGGCARTGYTCNYTNGARATG GARAAYTCNGARTAYMGNGCNATHYTNGAYTCNGTNTTYATGTTYYTNGGNAARTTYCAR GCNYTNAAYYTNACNACNGARGARAGYGTNATHYTNAAYGCNYTNGTNATHATGGCNCCN GAYMGNGGNAGYGARGTNAGY---TCNGARGTNATHTCNGCNATHTAYAAYCAYYTNGTN AAYYTNYTNATHTAYGTNYTNGGNAARMGNTTYGAYMGNCCNATGYTNATHTTYGCNAAR YTNATGGGNYTNATHACNGARTGYMGNTCNAARGTNGARGARATGAGYAAYGGNTTYAAR GAYTAYAAYYTNYTNMGNTAYATGCCNATHAGYGAYAARCCNYTNATHCARYTNATGTAY TCNGGNATHTAY------------------------------TTYGCNTGYYTNAARACN GARGARGARATHGCNGARGARMGNAARGCNMGNMGNAARYTNGARCARCARAGYCAYGAR AGYTCNTCNAAYAARAARAARAAYAAYAARCCNAARAARACNACNGARAARGARMGNYTN CARCARYTNGCNTTYGGNTTYGCNAARCCNGGNGCNGCNAAYCCNGARCCNCCNAARGCN TCNGCNGGNAARTCNGGNAARAAYAARAAYTCNTGGGARCARTGGAARGARCAYGAYCAR GARGTNGTNGARGAYCARTAYMGNGARGAYYTNGARAARGCNYTNATGGARAGYCARYTN CARYTNGTNAARAARAARACNGARGARAARCARAARAARGARMGNATGAAYTCNGCNACN GARCCNACNATHGARGARGARGARGGNAARAARAARAARAARAARGAYAARACNAARACN ATGTCNYTNGGNGARTTYAAYAAYYTNCARAAYCCNAARCCNCARAARATHTCNGARGAY TCNCCNGAYGARGAR---------CCNTCNMGNCCNCCNATHCAYCAYMGNGTNCCNTCN GCNGAYAARGAYTCNAARTTYTTYAAYAGYGCNCARCAYGARGCNAARCARATHYTNAAR AARGAYAARATGCARGARGARTAYMGNAARACNTGYGCNGTNGAYAAYGCNGTNGTNGCN AARYTNAARTAYGAYATHGARYTNMGNGAYAARACNATHAARGAYYTNAARCARAARGTN GARAARAARGARACNGARATGAARCARGTNAARCARMGNAAYAARCARYTNTGYGARATH YTNGCNCARGGNGARATGAARGAYAARGCNCARGTNYTNYTNCARGTNGAYGARYTNAAY AAYGTNAARGAYGARYTNATGGARCARGTNACNTCNYTNACNGCNGARYTNGARAARGAR AARTCNAARAAYMGNTCNYTNAARCCNGARGCNGAYAARGCNAARGGNGGNAARCAYGGN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GGNAAR TCNMGNAARAGYCARAAYCCNMGNMGNCAYCCNCARGTNAAYGARAARGAYTAYGAYACN TTYGARATGGARGTNGARGARATHGAYGARAAYGGNAAYGAYTCNCAYTCNGARMGNGTN YTNTAYCCNTCNTCNTCNCAYGAYAAYTCNGGNGAYCAYMGNGGNTCNCAYATGCARYTN ATHCCNTCNYTNCARGAYGARTCNCAYGGNTTYACNGCNACNCAYGTNTCNMGNCCNACN GTNCCNCCNATHMGNGCNCCNCCNACNTAYYTNGGNAAYCARMGNGGNMGNACNGCNAGY GCNTCNAGYYTNTAYTGGAGYTGYGGNTAYTGYGAYTTYCARAGYAGYAGYCARGCNGAR ATHAARGARCAYTCNAAYMGNACNCAYCCNGGNAARCCNCAYMGNTAYGTNGCNYTNATH AARAAYATGACNCCNGAYTCNATHATHAAYAARAAYACNAAYGCNTCNCCNTCNYTNMGN TCNCCNGCNGTN---------AARAAYACNCCNTCNTTYTCNTCNGTNAARYTNGAYAAY GTNGCNAAYAARTTYGAYMGNGARGGNGCNGGNGCNGGNGAYGAYATHGTNAAYYTNTCN AAYAAYGCNGAYGARAGYACNYTNAARGTNAARATHGGNACNCCNMGNGGNCCNAARAAR GAYAAYGCNACNTAYAARTGYTAYCAYTGYACNTAYACNGCNAARMGNCAYTCNTCNATG AARTCNCAYATHTAYTAYAARCAYMGNGGNAARGGNYTNYTNGCNGTNGAYGARGAYACN AGYACNGGNGGNCARGTNTTYTTYTGYGCNMGNGAYGAYTGYACNTTYAARTCNACNAGY CCNACNTCNTAYYTNAGYCAYGTNGARCARTGYACNCCNTGGCAYAARCCNGARYTNGCN GAYGTNGARGTNGARCCNCAYATHMGNGARTGYYTNCARCARACNGTNACNTTYGCNGAR ATGGCNYTNGAYAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNAAR GCNATHATHATHAARGTNGCNGCNATGGGNYTNYTNCCNGAYAARCAYYTNGGNATGGAR YTNAARGAYATHTTYCCNCAY---------ATGAARCARAARTTYGGNYTNAAYGARTGY GGNGARGGNGGNGARTAYGARACNTTYGTNTTYGAYTGYCCNATHTTYAARAARTCNATH YTNATHGARGARAARGARYTNGTNATHCAYTCNAAYGAYGCNTTYGCNCCNGTNGGNTAY YTNAAYYTNMGNAARTGYAGYYTNCARCARAARCCNGARCAYGAYGTNGCNACNTTYGTN AARGAYATHGARAARTAYCCNATGTCNACNACNGCNAARTGGYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TGYGTNCCNTGYTCNAARAAYGAYAARGTNAAR ATHMGNAGYAARAAYAAYTTYTGYTGYACNGAYGTNAARACNCCNGAYYTNGGNGGNGCN CCNGCNATGATGACNAGYGCNGCNCAYYTNATGYTNAAYGTNGARCARACNAARGARAAY CARCARMGNAARGCNGARMGNCCNYTNGCNTGGATHGCNCAYGAYCCNAARAARMGNTCN TTYGTNMGNAAYGAYYTNACNTAYACNAARGGNMGNATHGTNGTNCARTCNAARGGNYTN TAYCAYYTNTAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AARCARGARATGGCNTAYAARGARATHCARAAYACN AGYTTYGTNGARGARYTNGARGARCARGTNYTNGAYYTNTCNGAYGARYTNCARYTNMGN AARATHMGNGARGAYGARCARMGNAARATGTTYGTNMGNGARAARCARAAYATHATHGAR GARATGGARGAYATHATGGAYGCNGARAARGARAARGCNAARATHGARGAYMGNTAYMGN MGNYTNCARGARACNYTNAARTCNYTNCAYCAYGAYYTNAAYACNACNAARGTNGAYAAR GGNAARAARACNAAYGGNATHYTNMGNTCNCCNTCNCCNAAYGGNACNCCNAARAARMGN AAYCAYGTNMGNATHTCNACNACNACNCCNACNAARGARTTYGAYGCNAAYGARCCNATH YTNACNACNCCNTGYCAYACNCCNCCNCCNATGGCNYTNACNGAYGAYGARTTYMGNTCN AARTTYYTNCCNGARACNCCNCAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG AGYGAYGARGAYMGNGARATHGAYATHGARAGYGAYGCNGAYGAYGARGAYGGNYTNGGN GCNTTYAGYTCNGTNGAYGAYAARMGNGCNCAYCAYAAYGCNYTNGARMGNAARMGNMGN GAYCAYATHAARGAYAGYTTYCAYAGYYTNMGNGAYTGYGTNCCNCARGAYGAYAAYAAR ------ACNAAYTCNTCNAGYAARACNTCNMGNGCNCARATHYTNMGNCARGCNTCNGAY TAYATHATHMGNATGMGNGAYAARACNTCNCARAAYGAYMGNCAYATHCARATHYTNAAR CARCARAAYGAYGARYTNCARGCNCAR--------------------------------- ------------------------------------------------ATHAARGCNYTN CARAARTCNCARACNGGNGGNAARGCNYTNATHAAYTCNAGYTTYYTNGARGAYMGNGGN GAYGAYGAYTAYGARAGYTAYGARGAYGARCCNGTNGTNGCNTCNCCNCCNAARMGNAAR AARGTNAARACNAGYCAYAGY--------------------------------------- ---------------------------------------ATHGTNGGNYTNGGNAAYTTY CCNCAYCCNGAYACNMGNCAYAGYGTNGGNATGMGNGCNYTNGAYGAYTTYTCNGAYMGN YTNGGNYTNACNTGGGARAAYATHYTNGGNMGNAARGGNGGNYTNYTNTGYAARACNGAR ATGAGYAARGAYCCNACN---------CARATHTAYYTNTTYAARCCNAARTCNYTNATG AAYATHTGYGGNGGNAAYGTNGCNMGNACNGCNAARTCNYTNGGNGTNACNTCNGAYTCN ATHTAYYTNGTNCAYGAYGARYTNGAYYTNGCNYTNGGNAARGTNTCNATHAARAAYGGN GGNAGYGCNAAYGGNCAYMGNGGNGTNYTNTCNTGYATHTCNGAYYTNAARTCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNAARGARAARYTNAARAARACNCAYGGN AARATGMGNMGNACNGGNTCNGARTAYCARTCNAAYTTYAARGCNCCNTCNGCNTAYTAY AGYAAYMGNGGNGTNTGGAARGGNGCNGAYCCNCCNCARYTNATGCCNGTNGCNAARGAR GTNGAYGCN---------------AAYGTNAAYAAYAAYGCNGAYGCNGAYACNGCNCCN YTNTCNAAYTGGTTYGCNGARGTNGTNGARYTNMGNMGNMGNGCNGAYGARTAYMGNAAR MGNGCNCARGGNACNCAYTTYTCNMGNGARCAYYTNGTNCARYTNATGGCNCARCARAAY GARTGYTGGGAYGTNGARTCNCARGCNTCNTCNACNGTNAARGCNYTNAAYYTNGARGCN CCNAARATHAAYAARAARTTYCARMGNGARGAYMGNGCN--------------------- ---------------------------------GAYTCNCCNGTNTGGTCNGAYATHGAR ATHGARGAYATGGARGARGARCARGTNGARCCNMGNGTNGTNAARAARAGYTAYAARTCN GCNTCNCCN---GAYGGNCARMGNATHGCNMGNATGAARMGNGAYAARGARGCNYTNTCN CARCARCARMGNAARATHAARGARAARGTNCARAARGARGAYATHGARYTNGGNGARGAY GGNGAYGARGAYGTNGTNGAYGARGAYGARGGNMGNCARCCNACNCCNAARYTNAARCAR ACNMGNACNTCNGCNAAYMGNCAYCAYYTNGAYYTNACNACNCCNGCNGTNGGNGGNGCN YTNYTNACNTGYCCNCCNTCNAARAGYAGYAARATGATHGTNACNTCNMGNTCNGGNGAY AGYTAYGTNACNGCNTCNGAYAAYATGGARGTN------GARCARAARAARTTYGAYATG GAYAAYYTNAARACNMGNCCNATHYTNGGNCARCCNTCNGGNGAYACNCAYGCNYTNMGN GAYGAYGAYGCNTCNTCNGAYMGNCCNYTNAAYACNMGNTAYGTNCCNTCNCCNGCNYTN ATHGCNAGYGAYGARGAYAARGARAAY---ACNCCNTCNAARAAYYTNTCNAARACNGCN AARCCNAGYAGYYTNACNCCNGTNCARGARGGNGCNGGNAARACNTAYATHAARTCNAAR CCNTTYYTNACNYTNGAYGAYGTNMGNTCNAAYGARATGGCNGCNATHGAYGAYGAYGTN ATGTCNGTNTCNATGATGTCNGTNGCNTCNAGYGCNTCNYTNGCNTCNGARGTNYTNGAR MGNGCNMGNAARMGNCARAARGARTTYTGGGGNAAR------TTYAARTAYTTYGGNTAY GGNAGYAAYATGYTNGARGARMGNATHCAYATHMGNAAYCCNTCNGCNMGNTAYATHGGN AAYGGNACNYTNAAYAAYTAYAARTTYGGNTTYGARAARACNGTNTGYATGTCNGARGAY ---TCNGGNGCNATHGCNACNATHMGNCCNAGYACNGAYAAYCAYATHAARGGNTGYGTN TGGGARATHGAYGCNGAYCARGTNGARAAYYTNGAYMGNCARGARTAYAAYTAYAARGCN GTNGARGTNGAYGTNYTNYTNGAYAAYAGYACNACNGTNTCNTGYMGNACNTAYGARATH AAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNGARTGYAARGTNGAYCAYCCNAARGGNACNGAYGTNGTNAARGCNGCN ATHACNAARATGAARTTYAAYAARCAYATHAARMGNGCNGARGGNCARAARCCNCCNAAR GTNGARYTNACNATHTCNGTNGAYGCNGTNAARATHATHGAYCCNAARACNAARGTNATG ATGCAYCARTAYCCNYTNCAYMGNATHTCNTAYTGYGCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARGAYTCNTCNCARCCNTCNCCNTCNGCNMGNGGNGTNAARMGN CCNCAYGAYGARATHGARGAYACNTGYGTNAGYTCNAAYTCNCCNAARCCNTCNCCNCAR AARAAYAARAARMGNTGYTTYACNTGYAGYTGYMGNYTNGARYTNGCNCARMGNACNATH GGNAARTGYMGNTGYGAYCAYGTNTTYTGYCCNATGCAYMGNYTNCCNGARYTNCAYGAY TGYGARTTYAAYCAYAARGARGAYGGNMGNMGNGARGCNMGNGARAARATGGTNAARCCN ACNMGNCAYATGGGNACNTCNTTYMGNMGNGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TCNGGNCARCAYAARCAR AARATHTAYATHAAYGTNACNYTNGARGGNYTNAARATHATHGAYGCNGTNGCNYTNYTN GTNYTNCAYACNCAYCCNGTNCAYMGNATHTCNTTYATHTCNMGNGAYACNACNGAYAAY MGNGCNTTYGGNTAYATHGTNGGNTCNGGNGAYGGNAAYCAYACNTTYTTYGCNATHAAR ACNGCNGCNGCNGCNGARCARYTNGTNYTNACNYTNMGNGAYYTNTTYCARGTNGTNTAY GARATGAARAARAARGARGTNGAYGAYGCNAARGARAARYTNGARAGYGARACNGCNAAR GARGAYACNACNGCNGARAAYGGNAARCCNTCNGGNGCNGGNTCNACNTCNGARGARGAY CARACNCARAARACNCARGCNGCNGAYGCNGAYGGNATHTAYCAYGTNCCNCCNAAYAAY GCNCCNGTNAAYGGNAGYYTNGARGARCARCARGCNAAYYTNYTNGAYYTNGARGAYCAR GCNGAYTCNATHYTNAARGGNATHGARCARATHAARAAYYTNGAYTTYGAYTCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNTGGGARATHGTNATGTCNGGNATHACNTGYYTNACNTGYAAYGTNGGNTTYGARGAY GTNGAYYTNGGNMGNATHCAYTAYAARACNGAYTGGCAYMGNTAYAAYYTNAARMGNAAR GTNGCNAGYYTNCCNCCNGTNACNTTYGARAARTTYGARGARMGN---------CARAAR GCNCARGARCAR---YTNGAYGCNACNACNAAYGARMGNTGYACNTGYAARCCNTGYAAY AARTGGTTYAAYACNACNAAYGCNTAYGAYAAYCAYYTNCARTCNAARAARCAYMGNGAY GTNATHTCNGGNGCNGCNCARATHAARAARGAYAARAARAARAAR--------------- ---------------------GCNGTNCCNAARCCNAGYGTNGARGARAAYATHTCNGAR GAYGARGAYGAYTCNGAYGCNGARTCNTGGGAYAGYTAYGAYGCNAGYATHATHGCNYTN GARGARTGYYTNTTYTGYTCNYTNGTNAGYCCNTCNATGGARGAYAAYYTNACNCAYATG ACNTCNTGYCAYGGNTTYTTYYTNCCNGAYGCNGARTTYATHTGYGAYYTNGARGGNYTN ATGTCNTAYYTNGGNGARAARGTNGGNGCNGGNTGYGTNTGYYTNTGGTGYAAYGARAAR GGNMGNMGNTTYAAYAAYTCNAARGAYGTNCARAARCAYATGATHGAYAARGGNCAYTGY AARATHTTYCAYGARCARGARACNYTNTAYGARTTYACNGAYTTYTAYGAYTAYTCNAAR AGYTAYCCNACNGGNGARGGNGARGAYTCNGARACNGCNGTNATG---GARAAYGTNGAY ATHATGGARYTNGAYGGNGAYGGNTAYTCNYTNACNYTNCCNTCNGGNACNGTNATHGGN CAYMGNTCNYTNATGMGNTAYTAYMGNCARAAYYTNGCNCCNTAYMGNCAYGARAARACN AARAGYGTNYTNCCNAARATGYTNGCNCAYTAYAARGCNYTNGGNTGGACNGGNGCNACN GGNCCNYTNGTNGARMGNMGNGCNAARGAYYTNCARTAYATGCARMGNATHMGNAARMGN CAYTTYATGAARYTNGGNATHCAYGGNAAYAAYYTNMGNCAYMGNYTNMGNYTNCARAAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GTNMGNYTNAARMGNACNGCNGAYYTNGARGAYCARCARAAY GAYGTN------------------------GARMGNTCNYTNGARGAYATHGARAARGAY YTNAAYMGNYTNMGNGARGARAARGARAARGCNAARGAYACNGARGARYTNATG------ ---------GARGARGARYTNGARGARGARAARCARAARGAYTGYCCNAARCAYATHCAR GTNYTNAARGARGTNYTNTCNMGNGTNAARAAYYTNYTNTCNTCNCAYGAYGCNMGNGTN MGNGTNCARTCNYTNGARGTNGTNACNCARAGYTGYAARGAYYTNGCNTGYCAYGARMGN GARYTNYTNCCNCARATHCAYCARGTNTGGCCNGGNTTYTAYCCNMGNTTYCAYAGYGAR GARAARTTYGTNGTNATHAARGCNYTNCARACNYTNAARGTNATGGCNGAYGTNAGYGGN AGYTTYATHYTNCARMGNGTNATGAARGAYGTNATHCCNGGNYTNTCNCARTTYATGGAR AARCARGGNAGYATHAGYTGYGAYAGYMGNTCNACNTAYGARAAYACNGCNAGYTTYAAR YTNCARATHGCNATHYTNGAYACNYTNGGNCCNYTNGCNGARAARYTNGARYTNAAYGAR MGNAAYYTNGAYGCNGTNGCNAARATHTGYYTNCCNTAYYTNAGYTGYYTNCARTCNGAY AARYTNCARAARGCNAGYATGACNTCNTTYAARTCNTTYATHTCNYTNGAYTCNGAYGCN ATGTGGYTNYTNYTNTGYCARGCNTAYTGYCCNMGNCAYTAYCARGTNCCNGGNGTNGAR TTY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYGAY CCNAARAGYGTNATHAARTAYYTNYTNACNTCNCCNGTNGCNGGNATGCCNCARCCNATG GCNACNACNGAYATHATHGAYTCNTCNCCN---------CARYTNACNCCNGCNCCNGCN GTNCCNGTNAARAARTCNAGYAARAAR------------ATHAARTTYGARGAYGGNACN AGYGCNCCNAARAARAARGARAARAARATGAARATHGARATHATGTCNCCNTCNGARATH GGNCCNCCNGTNTCNTCNGCNCCNCCNCCNGARACNAARGCNCCNAGYYTNAARATGAAR ATHATGTCNGGNTCNAAYCCNATGACNGCNCARGTNGCNATGGARTCNCARGAYAGYGGN ACNGGN------------------------CCNTCNCCNAARGTNAARAARTCNACNAAR AARATHAARGCNGARGTNAAYGARGAYGTNCCNGARYTNACNAGYCCNGGN--------- ------GAYGARGAYAARGCNCCNAARAARAARAARGTNTCNAARAARAARGARAARYTN ATHCARAAYGCNATHAGYGCNGCNAARCARATGCCNAAYYTNGCNGCNYTNGTNTCNACN CCNCARACNCAYATHYTNGGNYTNGGNGAYTCNCCNTCNCCNACNACNGTNAARCCNAGY ---------AARAARAARGCNAARAGYTCNCCNTCNGTNAARACNGARYTNAAYACNAGY AAYTCNYTNGTNATGGAYTTYGAYGARACNGGNATGGARGAYGARGGNGAYGARTCNACN YTNGTNATHGCNGARACNGARAARAARAARAARAARGTNTCNGCNAARAARAARAGYCCN AARGARAARGARGCNTCNAGYCCN---AARGCNGARAAR---GCNAARAARATHCCNAAR MGNGCNCCNACNGCNTAYATGYTNTTYTGYAAYGCNCAYMGNCCNGCNATHGTNGCNGAR AAYCCNGGNATHGARTTYGCNGGNATHAGYMGNAARYTNGGNGARYTNTGGCARACNCAR TCNAAYAARCARAARYTNCARTGGMGNMGNAARGCNCARMGNMGNATGAARAARTCNAAY YTNATHTCNACNGGNAARGCN---GGNGGNAARGARTCNYTNACNTCNGCNGCNTCNCAR GGNGTNGGNCCNYTNAAYTCNACNAAYAAR------AARYTNGCNYTNATGYTNCARAAR AGYAARCCNGTNGTNGTNGARGARGGNCCNYTNAGYCCNACNAARAGYTTYAGYATHGAR CCNYTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYAARATGAGYAGYGTNCAYCCNAAYGCNCCNCCNCCNCCNTAY--- ACNACNGAYCCNGTNTAYCCNCCN---CCNCCNGCNGGNTAYTAYGGNGCNCCNCCNCCN CARGCNTAYGGNGGN------------------GCNCCNGCNGGNTAYGGNCCNCCNCCN CCN---GGNTAYGGNGTNCCNCCNCCNCARGGNTAYGGNGGNCCNGGNCARCCNGGNTAY GGNCCNGGN---------------------TCNTAYCCNCARCARCARTAYCAYCCNCAR ------------GGNCAYTAYCARCARCARCCN---CARCARGTNGTNTAYATHMGNGAR GARMGNAAR------GARAARGAYAAYTCNGCNGARACNTGYTGYATHATHGCNYTNTGY AGYGCNYTNYTNTGYTGY------------ATGGCNGAYAGYAAYYTNCCNMGNCARGAY TTYGCNCCNCCNTGGYTNAARTTYCCNTCNGARACNGTNAARTCNTCNAAYCARAARTCN AAYTCNTAYCARGGNGAYMGNAAYMGNCCNMGNMGNGARGAYCCNTAYTAYTCNMGNTCN GAYTTYAAYMGNYTNCAYMGNCARAAYTCNYTNGAYTTYCAYGARAGYAARMGNTAYCCN TCNGTNCCNAGYAARTAYMGNCAYCAYTCNGTNGAYGAYGAYTAYGGNGGNTAYACNTAY GGNTAYGGNTGYTAYCCNTCNAAYTAYAAYTAYGARAARTAYGGNATGCAYTTYAGYTCN CARCCNTCNYTNGCNMGNACNGGNAGYMGNGAYGGNAARTAYCCNCCNGGNMGNGTNAAY CARGCNCAR--------------------------------------------------- ---GGNTCNMGNMGNGCNTAYCAYGAYMGNGAYTCNCAYMGNGAYGCNMGNAAYGGNGAY GTNAARGAYAARGAYAARACNTCNGARAARGAYMGNCCNTTYAAYGAYGAYTTYCCNTCN YTNAAYGGNTCNGGNGARTCNTCNGTNGAYTCNAARGCNAARCCNGCNTCNGGNGTNTGG GARAAYCCNCCNAARTCNTCN---AAYAARAAYGARGARTCNACNGAYYTNYTNAARAAY ACNTCNCCNGGNATHTAYAARGCNYTNGTNCCNAGYAARAGYGTNCARCCNAARAARCCN GTNAARGAYGTNTCNMGNGTNAAYGGNAGYGTNMGNGARATHTCNCCNYTNAGYCCNTCN AAYAARCCNGGNCAYMGNGARGGNTCNMGNTAYAGYCCNACNCCNGAYYTNGCNATHGTN ACNCARCCNAARAARYTNGGNGAYAARAARAGYGAYTTYYTNMGNGCNATHMGNAAYGAR AGYTCNATHMGNAAYGGNGARGTNTGYCARAAYCARAAYCARAARATGGAYCARAARCAR GARTCNAARCARGAYATGAAYGARAAY---------GAYGARAGYTCNGGNTAYAAYCAY ATGAAYGGNGAYCARCARGTNGAYACNAAYGARAAYYTNGTNAGYACNAARAARGGNGGN YTNAAYGGNGARATGAARGAYGARTGYATHAAYGGNGAY---------GCNYTNATHAAY CAYGTNGAYCAYATHACNYTNTCNGGNGARGARGARGARMGNMGNYTNYTNYTNTCNATG GGNTGGGTNGARGARGAYAAYACNGARTAYGARATHACNGARGAYGARATHMGNGARTTY CARAAYYTNYTNGARAAYCAYTGYCAYGGNCARMGNAAYGGNYTNMGNTCNACNYTNMGN AGYGCNYTNAAYMGNAARYTNGGN------ACNGAYGGNATGYTNAAYGGNATHTCNACN GARGAYGARAAR------------------TCNYTNAARAGYTAYACNGCNGGNAGYACN TGYCCNGARCCNAARGARGGNGTNYTNMGNYTNTAYAGYATGMGNTTYTGYCCNTTYGCN CARMGNACNMGNYTNGTNYTNGARCAYAARMGNATHCCNTAYGARACNGTNAAYGTNCAY YTNAARAAYAARCCNGAYTGGYTNYTNGARAARAAYCCNTTYGGNYTNGTNCCNATHYTN GARAARGAYGGNCARYTNATHTAYGARTCNACNTCNACNTGYGARTGGYTNGAYGAYATG TAYCCNGAYCAYAARYTNATGCCNGAYGAYCCNTAYAARAARGCNTGGGAYMGNACNYTN YTNGARAAYTTYGGNGCNATHACNGCNMGNYTNMGNGTNYTNTTYAARCCNGARACNAAR GTNGARGCNYTNCCNAARYTNMGNAARGGNYTNAARTAYTAYGAYAAYGCNYTNAARGAR MGNGGNGGNCCNTTYTTYGGNGGNYTNAARCCNTCNATGYTNGAYTTYTAYYTNTGGCCN CAYATGGARMGNTTYCCNGCNATGGCNACNATHGAYCCNGTNGTNGCNATHAAYAGYAAY GAYTTYCCNCARYTNCARGCNTGGTTYGAYGCNATGTAYCARYTNCCNGCNGTNAARGCN ACNATGTTYGAYATHCCNACNCAYYTNCAYTTYATGAARTCNATGTCNGARGGNAARCCN GAYTAYGAYTAYAAYYTNTTYGGNMGNTAYCCNMGNGARTAYAAYCCNAARGTNCAYGGN CCNTAYATGCCNGGNMGNTTYTAYGGNAARCCNGAYACNCCNTTYGGNCARGTNAARYTN GGNGARATGGGNTCNTGGYTNGCNMGNMGNAAYAARAGYCCNCARGGNATHTGGGCNGCN ATHCAYMGNTCNTAYTGGMGNTGGGCNCARGCNAAYYTNCAYGTNMGNCARAGYGGNTTY GTNCCNYTNGGNCARGCNGCNATGGTNYTNTCNATHACNTTYTTYGCNYTNYTNTAYAAR GARMGNAGY---------------------------------------------AARGAR GAYYTNGCNGARAGYMGNMGNAAYGCNGCNGARYTNAARACNACNATHTCNGGNYTNGGN GAYGAYYTNAAYAARTAYAARCAYYTNCARGAYGARAGYACNGCNGAYATHCAYYTNAAR AAYGARCAYYTNAARGARCARGARGTNGTNYTNTCNGARACNMGNCARCARYTNGTNATH TCNGARAGYCARYTNGARGTNGCNAAYGARAARACNGAYGARYTNGAYTCNGCNYTNGCN GGNYTNAARCARAARTAYAGYCARGCNAGYTCNCARATHGGNCAYYTNGARACNACNGTN AAYACNYTNCARGAYAARYTNACNGARAGYMGNAGYMGNGARATHGAYAARGARCARACN GTNGAYCARYTNMGNTCNGARYTNGAYGGNYTNGAYMGNGCNTAYTCNGAYAGYAARGAY GARYTNAGYAARTGYGARGAYATGATHCAYCARYTNACNACNGARYTNGAYTCNTCNCAR AARGARATHAGYTCNTCNCAYAARMGNATHAARGAYYTNGARGAYACNAGYMGNGARATH MGNGARCARYTNCARGAYGCNCARCAYCARGCNYTNCARAAYGAYGARMGNGCNCAYAAY TTYGARAAYAARYTNYTNTCNTAYCARGGNGARCAYAGYCAYTCNGAYMGNGARTTYYTN CARAARGARGARCARATHAAYTCNYTNGARTAYCARYTNGARGARACNAARAGYGAYGTN GARATGMGNCARTCNACNATHGAYCARATGAARTCNGAYYTNACNATHACNCARTCNGAY YTNACNCARGCNAARGARGAYAARAGYGCNGCNYTNAARGARATHGAYMGNYTNGARCAR CARAGYCARCARYTNCARYTNAAYYTNGCNTCNGCNCAYCARMGNCAYAARAGYGARACN TGYMGNTTYGARGARCARGTNTCNTCNYTNGARMGNCARGTNACNGARACNCARGGNACN YTNMGNAAYGCNGARTGYGARATHAAYAAYAARGARGARCARATHAARMGNAAYGARGCN GARATHGCNTCNTGYMGNGAYGAYATHMGNATHAARGTNGARGARATHGARMGNYTNGAR YTNTCNYTNCAYGARGCNMGNYTNGARATGAAYCARACNTCNGTNCARTGYAARCARYTN GAYAAYGTNATHACNGARYTNAARTCNGAYGGNGARAAYYTNMGNAARGAYYTNAAYGAR GCNMGNYTNCARTAYAARGAYTGYGCNCARGARYTNGCNCAYCAYGARGARAARYTNAAY YTNATGGARCAYAGYYTNCARTCNACNCARGAYCARYTNAGYCARMGNGTNACNGARATH GTNMGNCAYGARCARAAYACNMGNAARYTNCARGCNGARYTNAARGCNATHAARGARMGN GCNGARGCNTAYGARGARGARATGGARGARCARAARGTNATGATHGAYAARYTNMGNAAR GAYYTNGTNYTNTCNAARGARGARTAYCAYTCNTCNGTNCARGARGGNATHGCNTAYAAR CARCARGCNCAYAARAAYGARYTNGARYTNAGYGGNAGYMGNGARCARGARAARATGYTN TCNGAYCARGTNGARCARCARGARCARATHYTNAAYCARYTNCARACNGARYTNMGNGCN GARMGNGARMGNCAYGGNGAYACNGTNCARCARYTNAGYGCNAGYAARAARAAYGGNYTN GAYYTNCARGCNGAYGTNGARGCNATGCARAARCARGTNMGNGARYTNCARGAYMGNGTN AARGTNMGNGARGAYCARATGGTNMGNYTNMGNCAYGARATHGAYAAYYTNCAYCARAAR AGYMGNGARAGYAAYGARATGATGGCNGARAARGAYGGNCARYTNMGNYTNGCNGARATG AAYYTNCARACNGCNCARAARCARGCNAARCAYCAYGCNCARGARATHGCNMGNTAYGAR GAYACNYTNGCNCARYTNCARACNGAYYTNGARAARATHCARGARCARTAYMGNCAYTCN TCNTCNAAYYTNATGGARGCNGAYAGYAARGTNCAYGARYTNAARGTNCARYTNACNACN YTNCARGGNCAYCAYAARGARGCNATGGAYCARYTNACNGAYAARGCNMGNCARYTNGCN GGNATHAARACNGARGCNGCNAARATGGCNCARCARAAYAAYTCNATGAARGAYGARATH ATGATHTAYGAYGARAARGTNMGNAARYTNCARCARGARYTNMGNAARTCNCAYGARATH AGYAARGCNACNGARGARGARYTNCARCAYTTYGARGARMGNTAYACNAGYYTNCARGTN GAYYTNGTNTCNAGYCARGARAARCARAARCAYTCNYTNCARGARYTNTCNTCNAARGAR GARGARAAYGTNGTNGTNAARGTNGARYTNAGYTCNYTNCARGARAARTAYAARACNGTN AAYGAYGARGTNCAYAARYTNACNAGYGARYTNGARYTNACNAARCARAAYTAYMGNAGY GCNACNGARGARATHTCNGGNYTNMGNGTNGCNYTNGARGARTCNMGNGCNAAYGGNGAY MGNYTNCAYMGNGARAGYGARYTNGTNGTNCAYAAYGTNAAYACNTGGGTNCARGARCAR AARATGGCNAAYGARAARYTNGGNAAYAARATHMGNGARCARAGYAARTCNATHATGGCN YTNACNTCNGARAARGARTCNYTNYTNGARCARGTNGCNAARYTNCAYAARAAYTAYAGY MGNACNMGNACNGARYTNGARGAYAARACNATHGARGGNGARAARYTNMGNGCNYTNCAR TCNCAYTCNGCNCAYCARCARGTNATHYTNAAYCARYTNAARAGYMGNYTNGARGARCAY GARYTNGAYAARGAYGCNGAYYTNAARACNAARGTNGCNACNATHGARGAYYTNCAYTAY MGNYTNAARTCNAAYATHGAYAGYATHCAYCARYTNAAYCARCARYTNAGYACNYTNCAR AARGAYAAYATHMGNYTNMGNAGYGARYTNGAYMGNGARATHTCNACNMGNCARAGYYTN GARATGCARGTNCARGGNAARGAYCARYTNGTNGARTCNYTNMGNTCNCARYTNGAYTCN AAYTCNTAYAARCARYTNYTNGARAARGCNGARAAYTAYAARGAYCCNGARAARYTNGTN MGNACNACNYTNAGYAARACNGCNGARGARACNGGNGTNCCNGAYCCNCAYAAYYTNGAY AARTCNTAYTGGATHCARMGNGTNGGNGAR------YTNTCNATHCARYTNCARCARAGY AGYGARTAYTGGTCNGAYAARGTNMGNGAYYTNTCNGARCARYTNGARAARTCNMGNACN ATHTCNACNGCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AGYGAYAGYGARMGNAAYGARGTNTCNGAR AAYYTNGTNTCNGCNTAYAARAAYATGACNAARGARGARYTNYTNMGNGTNGCNATHCAR GCNAARGCNCARATGATHMGNAARGARAARTAYATHAARGAYYTNGARAAYTAYATHGAY GAYYTNYTNGTNMGNGTNATGGARACNACNCCNMGNYTNYTNACNMGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYMGNTCNACNMGNAAYYTNGCNGARMGNGTNGCNGTNYTN MGNMGNGARAARGARATHATHTAYMGNAARATHCARGARGTNCARCARCARCARGARGTN GAYMGNCARMGNGARCARTTYCARCARCAYMGNAAYYTNCAYAGYCARMGNAARGAYGAR YTNYTNGARACNYTNMGNATHYTNAARGARAARYTNGARGARCARAGYAARACNYTNCAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYGAYGAYGAYGAYGARTCNGARGAYGAYTCNAAYYTNACNGAR GARGARMGNGCNMGNAARAARCARTTYATGATGAARMGNAARATGCAYTAYAAYGARTTY CARGCNGTNCARYTNGCNAARAARYTNATGGCNGARGAYAARGAYGAYGAYGAYGAYGAY GAY------------------------GAYYTNMGNATHAAYCAYTTYGAYATHGGNGAY ACNATHGCNCARMGNMGNMGNMGNGCNGGNGTNTTYAARAAYCARTCNGGNCCNCCNCCN GARMGNMGNAGYACNATHAGYAGY---ATG---ACNAGYAGYTAYCARGTNACNMGNATG MGNAAYYTNTCNGGNGGNAGYAGYGGNAGYACNGCNAGYGGNAGYAGYAGYGGNAGYTCN GTNCARYTNGAYAAYCARTAYTCN------GARAAYAAYCAYGTNTAYTTYTCNTGYTAY ATHCCNCCNTTYGCNAAYTCNTCNTCNGCNGTNCCNAARCAYAAYGARGAYTCNGCNTCN ACNTCNCAYMGNAARYTNGAYMGNAGYYTNAGYGAYAGYGAYACNGAYMGN--------- ---------------------------TCNGGNAGYMGNTAYAARACNGARYTNTGYMGN CCNTTYGARGARAGYGGNTCNTGYAARTAYGGNGAYAARTGYCARTTYGCNCAYGGNTCN CAYGARYTNMGNAAYYTNGCNMGNCAYCCNAARTAYAARACNGARYTNTGYMGNACNTTY CAYACNATHGGNTTYTGYCCNTAYGGNCCNMGNTGYCAYTTYATHCAYGARGAYGAY--- ---------------------------AARGGNCCNCCNAARYTNAGYAGY--------- ------AGYGGNAGYGGNAGYAGYAGYCCNTCNYTNAGYCCNACNYTNCAYGAYCARAAY ------AAYTTYTCNTAYTCNTCNGARTCNTCN---CARYTNAAYATHGAYAAYGCNMGN ATHAAY------AGYTCNYTNACNGTNAAYATHAAY---TAYGGN---------AAYGCN GAYYTNCARTCNYTNGARCAYCAR---TTYAGYTCNGCNYTNGAYYTNAAYMGNAAYTGY ------AAYGARTCNTCNMGNAAYGTNTAYAGY--------------------------- ---------AARTCNAAYGARTAYGAYATHTTYAGYTCNATHTCNGTNTTYAAYGCNGAY GARGTN---GTNGAYAAYGCNCAYYTNAARCCNTCNAAYTCNTAYTCNTCN---TCNCAY TGYAAYCARAAYYTNGAYAAYTAYCCNGGNTGYGTNAAYACNTCNTGYTAYTGGCCNTCN ------AAYATGTCNTCNCARAGYATGGCNCCNGTNGAYCCNTTYAAYTAYTCNCCNACN GGNTCNACNGGNTCNACNAGYTCNTCNGGNTCNTCNGAYTCNAGYAGYGGNAGYGAYTGY AGYGGNAGYACNGARAGYYTNGTNAGYTCNGGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AGYTGYGGN CCNTGGTAYGAYYTNGARYTNTAYATHMGNGARAARYTNGTNYTNAAYAAYAARAGYGTN TAYGTNTGYTCNGGNCCNYTNTTYYTNCCNGTNGAYGARGGNGARAARATGGTNAARTCN TTYGAYGTNYTNGGNGAYGGNGARGTNTCNGTNCCNACNCAYTTYTTYAARGTNATHGTN ATHGARACNGARGAYGGNCARYTNGARYTNGARTCNTAYATGYTNCCNAAYAAYTCNGGN GAYGGNGGNGGNGARACNAAYYTNGAYGARYTNYTNACNCCNYTNTGYCARATHGARCAY CAYTCNGGNYTNATHTTYTTYCCNGAYAARAAR---TGYTTYAGYAGYAAYAAYAARMGN MGNGGNGCNAARYTNCAYGCNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARACNTTYCAYGTNATHCCNCCNCCNCCNCCNYTNATGGARAAY GTNTTYGCNGGNMGNMGNGAYGTNMGNAAYCCNAARTCNGTNCCNGARAARGARATHGTN AGYAAYAARGGNACNGTNMGNGGNTTYACNAAYMGNGTNMGNGCNGGNATHGCNACNTTY TGGGCNCARCCNGARGAYGARMGNAAYTAYMGNCARYTNGARAARGGNAARATHGTNGTN TAYGCNACNTCNATGAGYGTNGTNMGNGARACNAGYGARMGNTGYAARTCNGTNMGNAAY ATHYTNCARAAYCAYATGGTNMGNTAYGARGARMGNGAYYTNTAYATGAGYMGNGARATH CARYTNGARYTNAARCAYMGNYTNGCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GCNCARATGACNCCNGGNTTYGTNGGNGCNGAYYTNMGN GGNYTNTGYGARGARGCNGTNGAYTAYGCNCARAAYMGNTCNTCNGARGARGARTCNACN YTNACN------ATGGARCAYTTYTAYCAYGCNYTNCAYAARACNATHCCNTCNYTNAAR AARGGNAGYGARTGYGTNGTNGAYYTNACNCCNGTNMGNTGGGAYGAYATHGGNAGYYTN GAYCARATHAARGCNGARATHMGNCARTCNATHGARTGGCCNYTNATHTAYCCNGARGTN YTNMGNMGNATGGAYYTNCCNCCNGCNAARGGNATHYTNYTNTAYGGNCCNCCNGGNTGY TGYAARACNACNYTNGTNMGNGCNGCNGCNACNTCNTGYAAYGTNTCNTTYYTNTCNYTN AGYGGNGCNCARGTNTAYTCNGCNTAYGTNGGNGARTCNGARMGNYTNATHTCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNGGNAARAARATHATH TGYGAYCARTTYGTNGCNGGNCCNTTYTTYTGYACNATGTTYYTNTAYGGNTCNACNATH YTNGARGGNAARGGNTTYGCNGGNGCNAARGCNGARTGGAARGCNAARTTYYTNCAYATH TAYATGATHGAYTGGGCNTTYTGGCCNGCNGCNCARTTYATHAAYTTYAARTTYYTNCCN ACNMGNTTYMGNGTNYTNTAYGTNAGY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------YTNAAY ACNATHCAYGTNGAYACNGAYYTNGARACNGARCARAAYGAYYTNGCNGTNCARGCNAGY ATHYTNYTNGTNCARGGNYTNMGNTAYAAYGGNGAYATHACNAARCCNGCNGARGAYAAR ACNAAYTCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNATGACNGTNTTYYTNGAYGTNTTYMGN MGNGCNGAYAARAAYGAYGAYGGNTCNATHTCNTGGGARGARTTYGTNTCNTAYTTYGCN GAYGGNGTNATGGGNAARGARGARYTNCARACNYTNTTYAAYGARATHGAYTCNCAYAAY ACNGAYAAYATHGAYATHGGNGARYTNTGYGCNTAYTTYTCNCARCAYYTNGGNGAYTTY CARGARATHTTYGGNYTNGTNGARGARATGAAYAARAARATGACNGCNGTNYTNTTYAGY ACNTCNAARGTNTAYAARGAYTCNTCNMGNACNGAYAARTTYGTNACNMGNTTYYTNATG MGNGARATHYTNAAYCARATGGGNGCNYTNCARMGNCCNYTNGAYGCNGCNTCNGARGCN YTNGAYCARCARGCNMGNGARGARMGNTCNGAYATHCARCCNYTNGARGTNTCNGAYATH ATHAARAARTCNGGNAGYGAYAGYGGNATHGTNCCNGGNMGNGTNGTNMGNMGNGCNAAR MGNCARGTNAGYAAYTGYAGYTCNYTNGGN---------------------GCNGAYGGN CARACNAGYYTNAAYGGNCARYTNGAYAARYTNGCNMGNYTNGTNGAYAARYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GTNATHTTYTCNTCNATHGCNGTNATHYTNATHGTN ATHGTNGCNTAYTTYATGTGGAARAARTAYCARCAYMGNCARMGNATHYTNMGNATHTTY MGNCARGARCARAAYGAYCCNTTYCARGCNYTNTAYAGYCCNGCNCARGAYGCNTAY--- ------------AGYGAYAAYATHMGNCCNTGYMGNTCNTAYGARACNATGGAYAARYTN GCNGGNYTNACNCAYCAYCCNGAYATHMGNYTNTGYGCNTCNAGYCCNGGNATHTAYGTN CAYCAYTCNMGN------AGYCCNGTNMGNTCNGCNAAYGCNAGYAGYGAYGAYAGYGAY CARGCNTCNGTNGCNGCNAARGCNTCNMGNATGGTNGAYGTNYTNACNGARGARAAYMGN GCNYTNMGNGARGARYTNGCNACNGCNACNGTNAARGTNAAYMGNYTNTCNAARTTYGAR GTNGARGTNCAYAARATGCAYGAYGCNCAYGTNTCNYTNYTNGARTCNCAYCARAARMGN GARGCNYTNTGGYTNGCNATGMGNMGNAARYTNGARGARMGNATHCAYGGNYTNGARGGN TAYGCNCCNGCNGGN------TCNCAYGGNGAYTCNCCNAARCCNATGTCNGTNACNGAR TCNGARYTNMGNACNMGNATGGTNGARAARGARTCNYTNGTNGCNMGNYTNYTNGCNCAR AAYCARGARYTNGTNTCNAAYMGNAARCARYTNGARGCNGARAAYATHCARYTNAAYGTN ACNYTNGCNGARCARMGNGCNMGNGTNGARATHGTNGARAARGCNYTNGTNAAYTGYCAR GCNAARGTNYTNATGGGNGAYGARGARTAYCARAARAARATHTCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TGYCARAARMGNCARGTNTAYATGAARGARATHCARMGNYTNAARGARACN TCNATHYTNGARGCNTCNGCNCCNGGNCCNMGNGGNTCNYTNACNATHAGYGAYATHMGN YTNCCNYTNAARAARGAYTTYGTNAARAARATHGGNACNTCNCAYGAYTAYACNACNCAY TTYTTYATHYTNYTNATHMGNAAYGGNTGYCARGTNATHTGYACNCARATGYTNTCNACN CAYGAYTCNATGATGMGNGGNAGYYTNGAYTTYCCNAAYYTNATHAARATHAAYGGNATH GGNGGNGAYTTYAARYTNGCNGTNGAYATHTAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYTTYGGNCCNTCNGCN YTNGGNACNCARGARTAYTGGGAYGAYGCNTAYGARAARGARYTNGARAAYTTYGAYGAR ATHGGNGAYGTNGGNGARATHTGGTTYGGNGARGAYACNCARAAYMGNATGGTNAARTGG ATGTGYAAR---AARTCNATHTCNAARTCNTCNAARATHATHGAYYTNGGNTGYGGNAAY GGNATGYTNYTNYTNGCNYTNMGNCARGARGAYTTYAGYGAYYTNACNGGNGTNGAYTAY TCNGARTTYTCNGTNAARYTNGCNAAYAARGTNTGYGARGCNGARCARATHAARGAYGTN ACNTTYGARGTNTGYGAYATHYTNTAYTCNTCNGAYGTNGARAARTTY------AARGAY ACNTAYGAYGTNTGYYTNGAYAARGGNACNTAYGAYGCNATHAGYYTNAARAAYACNAAR GAYCCNACNGAYMGNCARACNTAYGTNGAYCAYGTNTCNTCNATGYTNAARCCNAARGGN CARYTNATHATHACNTCNTGYAAYTGGACNAARGAYGARYTNACNAARCAYTTYTGYAAR GCNTTYCAYYTNACNGAYGARATHCCNGCNCCNAARTTYACNTTYGGNGGNCARACNGGN CARAARGTNACNACNYTNATHTTY------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TCN GARGTNCARCAYGCNYTNAGYTGYATGGCNAARGAYAAYMGNYTNTAYYTNGTNGCNAAY ATGGGNGAYATHGTNCCNTGYAAYGCNAGYGTNGAYCCNAARTGYCCNCCNAAYGGNCAY TAYCARTAYAAYACNGAYGTNGCNTTYGAYCCNGARGGNMGNYTNGTNGCNAARTAYCAY AARACNCAYYTNTTYTAYGARACNCARTTYGAYACNCCNGGNCCNGARGTNGTNTAYTTY GAYACNCCNTTYGGNMGNTTYGGNATGYTNGTNTGYTTYGAYYTNYTNTTYAARAAYCCN GCNGTNACNATGGTNACNGARCAYAAYATHTCNAAYATHGCNTTYCCNACNGCNTGGATG GAYGCNYTNCCNYTNYTNTCNGGNATHGGNTAYCAYTCNTCNTTYGCNMGNGGNYTNGGN GTNAAYTTYYTNTCNGCNAAYATHCAYYTNCCNAARTCNMGNTTYCAYGGNAGYGGNATH TAYACNCCNGAYGGNATGGCNAGYTTYTAYTAYGAYAGYGAYCCNMGNTCNCCNGGNAAR YTNYTNGTNTCNACNATHGAYATHATH--------------------------------- AARCAYAAYGCN---TCNAGYGARATGGCNAGYAARATHTCNCCNAAYYTNAAYGGNAAY GGNGAYGARTTYAARTCNCARATGTTY--------------------------------- ------------------------------------------------------------ ------CAYGAYCARTAYACNTTYAARYTNYTNGARGAYAARTCNGGNAAYYTNAGYGTN TGYCARAARAAYGTNTGYTGYTCNYTNGTNTAYAGYTTYTCNGAYGARCCNAAR---AAY GARYTNTTYGCNTTYGGNGTNTTYGAYGGNYTNCAYACNTAYGARGGNCARTAYTAYTTY CARATHTGYGCNGTNGTNAARTGYGCNGAYAAYYTN---GAYAARGGNTCNTGYGGNGCN CCNACNACNGCNTCNAAYACNACNTTYGARTCNYTNTCNATGTCNGGNGARTTYCARACN GARTTYGTNTAYCCNCARATHGTNYTNTCNMGNAAYGGNCARYTNGTNYTNGGNGAYCAR GCNTCNTGGAGYTTY---CARGGNACNACNYTNGCNTCNGGNCCNACNYTNGAYCARCCN YTNGTNACNGCNGCNYTNTAYGGNMGNTAYTAYTGYMGNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNAAYMGNTAYAAYCCNYTNCCNCCNGCNCCNGCN CCNAARCCNAAR------------GARATHGGNYTNACNGAYCCNTAYGTNAGYYTNTCN MGNGARTCNCARGARTTYGTNAARMGNGTNACNTCNATGGGNTTYYTNMGNGCNAARGTN TCNMGNGCNGTNGARAARTTYGGNCARGAYGARAARGARGTNYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNTCNTTY AARCARGTNMGNTGYCAYTTYATGAGYGGNTTYMGNAAYMGNGAYTTYCAYAARACNYTN ACNAARATGATGCCNAAYAGYGCNTGGACNTTYAAYGAYYTNAARTCNGAYACNAAYATH AARGARGCNACNAAYGAYAAYTAYAGYAAYGAYGARYTNAGYGAYATHACNTAYCAYYTN YTNAGYTAYTTYYTNYTNTTYAARTTYAAYTAYTCNGAYYTNGARCCNAARGAYTCNGTN ATHCARTCNAAYCARMGNTTYAARAGYMGNMGNGGNAGYTGYTTYATHGGNGARACNGCN GARATHGTNGCNACNCCNTTYGCNTCNYTNTGYCCNGCNGTNTTYTTYAAYGGNTAYAGY MGNGGNGTNATHAGYAAYGTNGCNGGNGTNAAYGAYTGYTGGATHGTNTCNGAYGCNMGN TGYATHCCNGGNTGYGARGGNGGNCCNYTNTAYACNAARMGNMGNCCNACNGAYAARGAY AGYTTYYTNACNGGNATHATHACNTCNCCNYTNTGYTGGAARAAYAAYGARTGGGTNGGN TTYTCNGTNGCNTGYAGYATHGAYAGYATHYTNATGTCNATHGCNCARAAYCARGARATH YTNYTNCAYGGN---------------------AGYGAYAARTAYYTNACNTCNGGNACN GCNMGNAARGARAGYAGYCCNYTNGAYAARAARYTNTGYAAR------GCNCARGCNGTN ACNGTNYTNGTNCARTGYGGNAGYACNTGGGGNACNGGNGTNATHGTNAAYMGNGAYAAR GGNATHATHYTNACNTGYAGYCAYGTNATHAARGGNGCNAAYCAYTGYTCNGTNACNGTN ACNCCNTCNAARAGYACNACNCARCAYMGNGGNCARGTNATHTAYMGNCARGARCCNGTN MGNACNGCNTAYGAYYTNGGNGTNATHAARTGYCCNCARGCNACNMGNCAYYTNCCNMGN GGNTGGTGYATHAGYGTNGCNCARGCNTGYGTNGGNGARGAYATGYTNYTNTCNGGNCAY GCNGTNTTYGGNACNGAYAARTAYYTNGARCCNTCNGTNAGYCARGGNGTNGTNTCNAAR GTNATHMGNATHGARGGNGARCCNGTNATGGTNCARACNACNTGYGCNGTNCAYGCNGGN TCNAGYGGNGGNCCNYTNYTNACNTCNGAYTGYMGNYTNGTNGGNATHGTNGTNTGYAAY ACNMGNGAYTCNGTNAGYAAYACNAGYTTYCCNCAYGTNAAYYTNTGYATHCCNATHTCN ACNGTNTGGCCNATHGTNCAYAAYTAYYTNTGYGGNGGNGAYAARGARGGNYTNTCNCAR YTNCARGTNAARGAYGTNGARYTNAAYAARYTNTGGGCNYTNGGNGCNCARACN------ ------------------------------------------------------------ ------------------------------------------GGNYTNGGNGTNAAYTCN AARTTYCARATHAARCCNTTYCARMGNACNTTYGAYGCNMGNTCNAARYTNGGNCCNAAR ACNGTNGTNGAYGCNMGNGAYAARATHATHATHAAYAARAARAGYGGNAARGGNGAYGCN MGNAAYAARATHGTNCARAARCARGTNCARAARGGNACNTTYGAYGCNMGNTCNYTNYTN AARAAYCARAARCAR------GCNAARAAYAARACNAAYGGNGCNYTNYTNAAYYTNCCN CCNCARCCNGAYTTYYTN---------GGNGCNGARCCNYTNACNMGNACNYTNTCNAAY CCN------ATHGGNCARATHGGNAAYATHCARGTNACNMGNCARGTNCCNGGNACNGAR GTNACNYTNACNMGNGAYTCNATGCARATHACNAARMGNGGNATGGGNGGNGCNYTNCCN CCNCCNTCNATHGGNGAYACNGTNCCNATHATHCARATHMGNAAYGAYMGNTAYCARCAR ---CARCARCARCCNCARCCNYTNYTN---------------CCNCCNCCNCCNCCNCCN CAYATGCCNCARCCNGCNCAYYTNGAYACNCARTAYTCNCARCAYCAYAGYAGYTCNTCN GCNMGNCCNTCNTAYATGTCNTCNTCNCARTCNCAYMGNTAYCARGAYYTNGAYAAYCCN GCNTAYAAY---AARTCNTCNYTNGGNGTNCAYCAYGTNCCNAARATGCAYGTNTCNAAY ATHAARGCNGTNGARGCNGCNGGNATGMGNCCNGTNACNTCNTCNYTNACNMGNTCNMGN CCNGCNYTNYTNCARCCNMGNGCNCCNCCNGGNGCNGCNACNYTNTCN------------ GCNAARCARCCNATHGCNYTNTCNCARCARTCNTCNTCNGGNGCNATHAARMGNMGNCAR CCNCCNGAYATGCARGARGTNGGNGGNCCNYTNMGNYTNGGNMGNGGNGGNGGNCCNGGN YTNCARGTNGGNATHGGNGARGTNTCNCCNCCNAARMGNGCNAAR------CCNGGNGTN CAYCCNTCNGARCCNATHGARATHTTYGAY---GARGAYAAYTCNAARTTYGTNAGYCCN ATHCARGGNTTYMGNGTNGTNGTNACNAAYYTNTTYTCNGGNGTNACNCARGAYGAYATH ATHGARYTNTTYGGNGTNGTNGGNCCNYTNAARAARGCNMGNYTNYTNAARGCNGGNTCN GCNGARGTNGTNTAYACNGTNMGNGARGAYGCNYTNAARGCNGTNCARAARTAYCAYGGN MGNGARYTNGAYGGNCARCCNATGTAYGTNAARATGACNACNCCNTCNACNGCNGTNGTN AARACNCCNYTNGGNCAY---GAYCCNGAYATHACNGGNGARGCNYTNMGNYTNTAYAAR AARCCNAGYAGYYTNGGNGCNYTNCCNGARGCNCCNATHGARGTNCCNACNATHCAYMGN GCNYTNTTYAARGTNGGNCCNCCNGCNCCNAAYAARTCNGTNAARTTYACNGTNAARATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGGTNGARATHCAYGARTTYTAYAAYGAYYTN GARGCNGCNMGNTCNYTNYTNGARGAYTAYAARGCNCARAAYCCNGAYAAYYTNAAYGCN CAYMGNTAYYTNTAYGARTTYGARATHAARCAYAARGARAARATHGAYGGNGARYTNCAY AGYYTNCARAAYATHATHMGNYTNGAYCCNAGYCAYCCNYTNGCNATHAARYTNTAYMGN GAYYTNGTNTCNTCNGAYCCNGARGCNGTNTCNATHYTNTTYGAYTAYYTNGAYTTYGAY CAYTGYAARAAYGAYYTNCARGCNTGGGARYTNYTNAGYAARCAYATHTCNAAYATGAAR GAYAARGARGGNGCNAAYACNGCNGTNACNCARTGYTGGMGNYTNMGNMGNGAYTGGTGG CCN--------------------------------------------------------- ---AARAARTCNCCNGARTGYTCNACNTGYAARGARATHGTNGAYAAYTTYCAYAARGGN YTNACNGCNACNGCNAARTCNAAYTAYGGNGGNGGNAAYACNAAYTGGGARGARAARTCN YTNGGNTCNTAYGCNTTYAGYGARGTNMGNYTNGTNGARATHGTNGARAAYYTNTGYAAR GAYAARTCNAARGARTGYCAYACNATGYTNGARGARCAYGARGAYYTNGTNGARAGYTTY TGGTTYAARGARTTYGCNAARAARTCNGAYAARGAYTTYCAYACNTTYYTNTGYATHGAR AAYATHAARGCNTGYTGYCCNAAYAAYACNTAYGGNAARAAYTGYYTNCCNTGYCCNGGN GGNGTNGARMGNCCNTGYCAYGGNAAYGGNAARTGYCARGGNGARGGNACNMGNGGNGGN ACNGGNAARTGYMGNTGYAGYGCNGGNTAYGCNGGNTCNYTNTGYCAYGAYTGYMGNGGN GGNTAYTAYCARGARAGYAARAAYGARACNCAYAGYGTNTGYAARYTNTGYCAYATHTCN TGYAAYGGNAAYTGYTCNGGNGARGGNCCNMGNGCNTGYGAYGARTGYAARGAYGGNTGG GTNAAYGAYCCNACNCAYGGNTGYAARGAYATHGAYGARTGYYTNGARGARCCNTGYGAR GAYGAYCARTAYTGYACNAAYACNYTNGGNTCNCAYTCNTGYTTYACNTGYAAYATHGCN TGYACNTCNTGYACNGGNGCNGGNCCNGAYAARTGYAAYGARTGYAAYAARGGNTAYATH AARYTNGAYAAY---GARAARTGYGARGAYCARGAYGARTGYAGYYTNGAYCCNACNYTN TGYACNAARTCNAGYGARGARTGYATHAAYACNCCNGGNAGYTAYGARTGYATHTGYACN ACNGGNTAYGARTAYAAYGARGAYAARGARTGYATHAARACNCCNAARGCNMGNTCNAAR GTNGTNAAR------ACNGARGAYATHCARTTYTCNGAYAARYTNAARATGGGNGGNACN GARAGYAARMGNMGNATHGTNGTNGARGAYGTNAAYGGNGARGGNGTNGTNCARGTNACN GAR---GCNGTNGTNMGNMGNATGAARGGNCARCCNGCNCCNCCNGTNCARAARGTNTCN AAYGARYTNCCNMGNGARAARGARTTYTCNAAYACNGARCAYMGNCCNCCNMGNAAYGAY GARMGNTAYMGNACNATGACNAARGARATHGARGAYTTYTAYATGGARAARYTNAAYGAY YTNCARAARAARAGYCAYGCNYTNCARGARCAYTCNAAYGARCAYTTYTCNAARGCNGTN AARGARGTNGARGGNAARTTYATGAARTAYACNACNTCNCCNGTNTGYCARGAYATHCAR ACNAARGTNYTNGARTGYTAYCARTCNAAYCCNGAYTCNATHYTNGAYTGYTCNTCNGTN GTNAAYGCNTTYACNACNTGYGTNGAYMGNGCNMGNATGACNGTNTCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GCNTTYAAYYTNGGNGCNATG ATGATHTCNGCNAAYAAYTAYATHGARGGNYTNTCNTAYYTNAAYAARGCNATHCCNCCN AAYGGNAARMGNGAYGGNMGNTCNAAYGGNGAYYTNTAYTTYAAYTAYGGNYTNGCNTAY GARGGNYTNAARAAYCCNAAYAARTCNAARTAYTAYTAYGARATGGCNYTNAARGARTAY MGNGCNGARAAYGAYAAYGTNAARATGGARGCNGAYACNATHGCNMGNATGAGYMGNYTN TGYGTNGARAAYAAYYTNYTNTCNGARGCNAAYGAYYTNATGAARCARYTNACNGTNYTN CAYTCNAGYCARGGNGAYGTNGARAARGARYTNCARTCNMGNGTNGARMGNTCNAAYYTN YTNYTNAARATGGGNMGNGCNCARGARGCNGARGARGTNGCNGAYGARTGYTTYAARGTN YTNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GTNATGATHTGG AAYGARTAYGARGCNTAYGTNGTNCARTAYAARCARATHGCNGTNTCNGCNTGYGGNCAR ACNGCNGTNYTNAAYGTNYTNAARGCNYTNAARTTYCARTGYGARAARTCNATHGTNTGY AARGTNATHAARACNAAYYTNMGNAARGARGAYAARGAYATHCCNGARTAYYTNTTYTCN MGNACNTGYGCNGGNACNACNGCNGTNGARYTNATGTCNGGNGTNGARAARYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARCARGAYAAYATHYTNGARGAYGAYMGNTTYAGY AARCAYATHGAYCARGCNMGNAARYTNGGNTTYTCNGARGARCARACNTCNAARGTNYTN MGNMGNYTNGGNGTNGAYGCNAGYATHGAYGAYATGATGMGNGARTTYGTNTCNAAYCAR GARGAYGAYATGGARMGNYTNGAYGARYTNGAYAAYGAY--------------------- ------------------------GAYAAYAAYYTNTCNTCNAARGGNGARGAYAGYGAY GAYAGYGARGGNTTYGAYGTNAAYGAYAGYTCNAAYYTNMGNCAYATHATHATHGAYGGN AGYAAYGTNGCNATGAGYCAYGGNCARAARGTNTTYTCNTGYYTNGGNATHAARATHGTN GTNGAYTGGTTYAARAGYMGNGGNCAYAARAAYATHACNGCNTTYGTNCCNCARTGGMGN AARGARGCNTCNMGNCCNGAYGCNCCNATHACNAAYCARGARATHYTNTCNGARYTNGAR GCNGARMGNATHGTNGTNTTYACNCCNTCNMGNMGNATHGGNGGNGCNMGNATHGTNTGY TAYGAYGAYMGNTAYATHYTNCARYTNGCNGTNAARACNAAYGGNATHGTNGTNTCNAAY GAYGTNTTYMGNGAYYTNGARMGNGARMGNGAYGAYTTYAARGARGTNGTNGARAARMGN YTNYTNATGTAYTCNTTYGTNCARGAYACNTTYATGCCNCCNGARGAYCCNYTNGGNMGN CARGGNCCNTCNYTNGAYAAYTTYYTNMGNATHAARCCNTCNGARCCNAARAAYAARCCN CARATHTGYCCNTTYGGNAARAARTGYACNTTYGGNATHAARTGYMGNTTYTAYCAYCCN GARMGNMGNTAYTCNTCNCARAARATGGTNGCNGARAARYTNAARGARAGYGCNGARYTN AARYTNAARYTNAGYAARGARACNGCNACNGARAARGGNMGNAARCCNAARCARAARYTN TCNMGNACNGTNTCNYTNGTNCCNCAR---GAYGCNGAYAAYGGNGCNACNTAYGARGGN CARACNAARAARCCNCARYTNCAYCAYTCNAARTCNYTNGTNTAYCCNAGYAGYTAYYTN ACNGAYYTNMGNYTNAARATGGAR---------------------------------AAR GCNGARGTNGCNGARACNGTNTGGCARTCNTCNTTYGCNACNATHAAYCCNGAYCARACN GCNTCNAAYGAYAAYCCNACNAGYCCNMGNACNTCNCCNACNCCNGTNCAYAGYTTYCCN TCNTCNCCNGTNCCNAARTTYCCNCCNAGYTCNTCNYTNAAYATHCCNAAYCCNGARTCN CARAAYMGNTAYYTNAGYGGNCAYYTNYTNGTNGTNAARAARYTNTCNGAYGARGAYAAY AGYAAYTTYTTYTCNAARCAYACNTCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARYTNYTNAAYYTNYTNGAYTCN GGNGARGAYCCNYTNATHAAYAARCCNATHCCNATHGGNGARAAYCCNCAYCARATHCAR TTYGCNAARGTNCCNAGYAGYGCNAAYGGNGCNTTYATGCAYAGYATGTTYCCNTTYACN AAYAAYGTNYTNATHACNMGNACNCARGTNGGNAARGAYGGNAARACNGTNTAYCAYGGN CCNGTNTCNGTNTTYTAYATHAAYTCNAARTGGYTNGARGCNGTNATGGAYTGYTGYTCN GARTTYTCNGTNAAYGAYTTYCCNYTN------ACNGCNATHGGNGAY------------ GAYGARGGNYTNAARAARATHAAYCCNGTNGAYAARMGNGGNACNACNAAYGARTCNGAY CARAGYACNAARTCNTTYGTNAAYGTNGGNGARGGNAGYGGNGAYGAYGAYGAYGAYGAY GAYCCNGTNTCNAAYATGACNMGNGAYGTNTGYGCNGAYATGYTNGARTCNATHCARAAR YTNMGNGAYYTNGARCCNAAYAAYCCNAAYATGAARAARATHGTNGARATGCARAAYAAR YTNAGYATHYTNCARACNTCNYTNMGNMGN------------TCNMGNACNTCNACNACN GCNAGYGARCARGARACNTTYTCN------------------------------------ AAYGARATGAARYTNAGYCCNGCNGARAARAARCARMGNGARYTNAARAGYGTNGARGAR AARTTYGARGARGCNGARMGNYTNGARCARCARGARGARGARCARATGAARCARMGNMGN GARYTNGARYTNCARAARMGNMGNGARTTYGARCAYAARAARAARTCNCARTGGGCNAAR AAYGTNYTNTCNGAYTTYAARAARCARGARGGNGTNGTNGGNGARAGYATGAGYGCN--- ------GAYGCNAARAARATHYTNCARCARMGNGARCARMGNATH--------------- ---------AARGARMGNGARGARGARGARMGNCARMGNAARGARGARGARATHMGNAAR CARGARGARGARGARAARYTNMGNGTNCARMGNGARAARGARGAR--------------- ---AARTTYMGNGARGCNGARMGNAARMGNYTNATHGARAARATHGARGARACNMGNTCN MGNGAYTCNCARAARTTYTCNTCNTCNCARYTNCARTGGAAYCCNTCNTGYAARATHCAR AARAARGCNYTNCCNTTYTCNCCNTCNGGNMGNTCNATHGARMGNCAYTAYTCNTCNGAR MGNGARGARTGYCARGAYGAYYTNATHATGTCNGARGARGARTAYCARGAYYTNGTNGGN CARATHCAYACNATHCCNAAYAAYYTNAARGTNAGYATHACNAGYYTNACNAAYMGNYTN TGYCCNGTNCARGAYTGYCCNTCNAARACNAAYTTYMGNAAYATGGARYTNTTYATGGAY CAYTGGGTNATHTTYCAYCARTCNCARACNACNATGMGNTTYTGYCCNMGNTGYTCNGCN TAYTTYATGAAYCCNGARGARYTNGARAAYCAYATHATGAARCAYCAYTGGYTNTCNTCN ---AARGARGCNATHGARYTNGTNMGNAAYGCNMGNACNAARGTNATHGCNAAYCCNAGY TAYMGNGAYCCNTTYCCNTTY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ AAYGGNCARTCNCCNGCNGARGCNYTNCAYAARTGGATHGTNGTNGAYAAYGARCCNCCN GAYATHTAYGCNATHGGNTTYCARGARYTNGAYYTNAGYAARGARGCNTTYATHTTYAGY GAYTCNGTNAARGARGARTGGCARAAYGCNGTNAARAGYTAYYTNCAYCCNAARGCNCAR AARGTNAARTCNGTNMGNYTNGTNGGNGTNATGYTNYTNGTNTAYATHCARGARAARCAY GTNCCNCAYATHAGYGCNATHGGNATGGAYTCNGTNGCNACNGGNATHATGGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARCAYGARGARMGNYTNGCNAAYTAYGARMGNTAY MGNACNYTNGTNGARAAYGARGCNTCNGGNYTNTCNGARGARTAYTGYYTNCAYCARATH TAYYTNGAYGARCAYTTYGGNACNATHACNAARCCNAAYGARGARGARAARAARAARAAY GCNGAYAARAARGCNGCNATHGGNTAYGTNTAYGARGAYAGYACNCCNGTNGARAARAAR GARCCNGAYGARGARAGYGARGARGARAGYGAYGARGAYYTNGAYATGGCNGAYYTNGAY GTNACNATHGAYGTNGAYTCNYTNACNCCNGAYATGTGYAARGARGTNAAYGGNATHGCN GGNCARTAYGGNATGGCNGARGAYGAYTTYGTNMGNYTNYTNMGNAARGAYAARGARGAR YTNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AAYCAYTCNYTNTGGGCNGTNYTNAAR YTNGAYCARCAYGARAARGCNAGYAARCARACNGGNGARTGYYTNGTNTCNYTNAGYGGN GTNGARGCNMGNATHGARGAYMGNYTNAARGCNTAYAARGCNAARAGYGTNACNGAR--- ------AGYYTNGAYTAYAGYACNYTNMGNGARGCNGGNATGGCNTGYCAYCARATGAAR ACNTGYYTNAAYGAYGTNTCNAARATHATHTCNYTNGCNYTNATHACNGARYTNCCNTCN ATGGGNGARATHGGNMGNTTYCCNGAY------------GTNGARACNGARAARYTNMGN GGNGARYTNTCNGARYTNCARTCNAARTAYAGYGTNYTNCARTCNACNGTNAARGARCAR CARGGNAARYTNAAYGTNTCNAARCARMGNCARMGNGAYTGGGARCAYTCNGTNTGYMGN CAR---------AARAGYAARMGNTCNMGNAGYYTNTCNGARTCNTTYGAYGAYYTNAAY GCNATGGARAARGARYTNGGNGARGCNTCNGAYGAYMGN------------GARATHATG GAYTGYMGNGAYGGNGAYCAYGARAARATGGCNCAYTTYAAYAAY---MGNATHYTNAAY CCNGARCARMGNGCNCARTAYGARCARATHAARMGNGCNTAYGCNAAYATHYTNTAYAAR TGGGGNYTNYTNAAYCARMGNGCNCARATHYTNAARCAYACNGTNTCN---YTNCARAGY TGYAARAARATHGARTTYTCNATHCCNTGYTCNAAYTGYTCNGAYGCNGTNATGAAYGTN CARTGYAAYMGNTGYMGNTAYCCNTCNYTNAAYTGYTCNATHTGYCAYGTNGGNGTNMGN GGNCCNGCNAAYGTNTGYYTNGCNTGYGGNCAYGGNGGNCAYTCNAGYCAYATGAARAAY TGGTTYCAYAGYAAYAAYCARTGYCCNAGYGGNTGYGGNTGYAAYTGYYTNMGNGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GARGARGCNTAYAAR MGNTGYCAYYTNYTNAGYAAYGAYAARGAYAAYGARATHACNYTNYTNAARTGYCARATH GAYACNYTNAAYGARAARYTNCARGAYMGNATHGCNMGNGTNGAYGARYTNGARMGNGGN ATHGARAAYYTNCAYAARGAYGTNGARMGNMGNATGCARMGNGTNGAYGARCARYTNMGN AARTAYGARACNGARYTNGTNGAYMGNYTNCARGARATHGGNACNYTNAARGARTGYATH AAYACNTGYCARYTNAAYYTNTCNGAYAARGARAAYGARYTNGCNCAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AGYGAYAGYACN GCNYTNGCNGTNGTNYTNTAYAARGARGCNGCNYTNYTNCCNCAYGARAARAARAAYMGN AGYTTYAAYATHGCNGGNAAYGARTTYTAYATHGARCARGAYTGGCAYGCNGGNGGNGTN GCNGCNGTNGTNTGGGAYGCNGCNATHGTNYTNGGNGARTAYYTNGCNTCNAAYGCNCAY YTNGTNCARGAYAARCARGTNYTNGARYTNGGNGCNGGNACNGGNYTNGCNGGNATGGTN GCNTCNTCNYTNGGNGCNGAYGTNATHGTNACNGARMGNGARCARGCNYTNTCNTTYYTN GARACNGCNATHTCNGTNAAYAARGCNGAYAARAAYTGGAARGTNAARGCNGARGTNYTN GAYTGG---ACNCAYGAYATHGAYTCNTCNAAR---TGGAGYMGNTTYGAYATHGTNATH GGNGCNGAYATHGTNTAYATHGARAGYACNTTYTCNCAYYTNYTNAARACNATHAARTCN GTNGCNAAYTCNCCNAARACNCARGTNYTNYTNTCNTGYMGNATHMGNTAYGAYMGNGAY YTNGTNTTYYTNAARATGYTNAARAARTTYTAYAARGTNGARGARATHTTYTAYAAYTCN AARYTNGAYATHAARATHTTYTCNGCN------------YTNGTNACNCAYTAYGGNGGN TGYCAYTGYGGNGCNGTNMGNTTYTCNGTNGARGCNGCNGCNCAYYTNGAYGTNATHGAR TGYAAYTGYGGNGTNTGYATHAARAARCARAAYCAYCAYTTYATHGTNCCNAARACNMGN TTYAARATGYTNCARGGNTCNGAYTCNYTNACNACNTAYACNTTYAAYACNCAYAARGCN AARCAYACNTTYTGYAARGTNTGYGGNGTNCARAGYTTYTAYACNCCNMGNTCNAAYCCN GAYGGNTAYGGNATHATGCCNCAYTGYGTNGAYCCNGGNACNGTNCARTCNACNACNGTN ACNMGNTTYGAYGGNAAYCARTGGGARGCNTCNATHAARACNTCNAAYATHGCNGARTAY TCNAARAGYCCNTCNTAYYTNGTNTTYGCNTAYGGNACNYTNAARMGNGGNGARCCNAAY GARAGYCARATG---GGNCCNGARTGGGGNMGNGCNGARTTYYTNGGNTGYGGNGARACN AARGGNAARTAYCCNYTNGTNGTNTAYACNTCNTAYAAYATHCCNTTYYTNATGCARGAR GARGGNMGNGGNTAYAAYGTNMGNGGNGARYTNTAYMGNATHGAYGAYAARATGATGGAY CAYYTNGAYGAYTTYGARTAYCAYCCNCAYYTNTAYGTNMGNAARGARGCNGARATHACN GTNACNAARGAYGCNCARGGNAAYGAYGTNACNCCNGCNCARACNMGNACNTGYTGGGTN TAYTTYYTNTCNMGNMGNCAYGAYGARATGYTNAARYTNCARTAYMGNCCNGARTAYAAR TCNGGNGAYATHGGNAAYCCNACNTAYGTNATHMGNGAYGARMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TGYCARTGYAARACNGARACNMGNAAY ACNACNACNATHAARGTNGTNGTNATHTTYATHATHTGYGTNGTNTCNYTNYTNTTYGTN TAYATGYTNTTYYTNYTNTGYYTNGAYCCNYTNYTNCARAARMGNCCNGCNAARTCNTAY CARCARCAYACNAAYGARGARGTNAAYATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MGNYTNACNGAYGTNYTNAAYGAY TGGATHAARAARTTYGARGCNMGNGGNATHCCNGAYGCNGCNTCNAGYGCNGARTAYATH ACNGCNCAYGCNATHGGNAARAARACNYTNCAYAAYATHAAY---ACNGAYAARTAYYTN ACNCAYGGNGAYGTNGTNGCNATHAAYAAYYTNAGYCARYTNMGNYTNMGNMGNATGCCN GTNCARTAYATHYTNGGNGARTGGGAYTTYGAYGGNATGACNYTNAARATGGCNCARCCN GTNTTYATHCCNMGNCCNGARACNGARGARYTNGTNGARCAYTGYAARCAYATHYTNAAR GARMGNYTNATG---------------------------ATHYTNGARYTNGGNTGYGGN AGYGGNGCNATHAGYYTNTCNYTNYTNAAYCAYTTYAARGARYTNCARGCNGTNTGYGTN GAYATHYTNCCNGARGCNTGYGCNATHACNAARACNAAYGCNGARAAYGTNGGNGTNGAR AAYMGNATHMGNATHATHAAYGGNGAYTTYACNMGNCAYAAYGTNATHTCNGARYTNGAY GCNYTNGGNCCNTTYTGYYTNYTNGTNAGYAAYCCNCCNTAYATHACNYTNGAYGARATG AARCAYYTNCCNCCNGARATHGAYGGNTTYGARAAYCCNGTNGCNYTNCAYGGNGGNGTN GAYGGNYTNGAYYTNGTNMGNCAYATHYTNTAYCARGCNCARACNYTNGTNATGCCNAAY GGNCAYYTNTTYYTNGARGTNGGNGARAGYCAYCCNGGNYTNATHGARAAYTTYGTNGCN AAY---AAYCARACNYTNAGYYTNCARTTYATHAGYGGNAARAARGAYATGTTYGGNMGN AAYMGNTTYTGYCAYGGNTCNCCNGARGTNGGNGCNGTNAAYTTYAAYGTNYTNCAYACN YTNYTNCAYGCNATGATHCARAARYTNAAYATHCARGAYGTNAARGCNGAYATHGARGAR CAYGAYMGNGARYTNYTNTCNACNCAYGGNATHCCNMGNGCNTTYTCNGCNTTYAGYGTN GGNGARGAYTCNYTNTCNGARGAYAAYYTNAGYGARAARTCNAGYTCNCAYGCNCAYAAR AARAGYCCNTAYCAYMGNYTNGARAARCARGTNTCNGARYTNACNAARCARATGGARGAR YTNAAYAARYTNCCNACNAAYGCNGARYTNATGGGNAARGCN---GGNAARGARTCNGAR MGNCCNATHGCNGAYATGTGGCARTAYATGCARYTNAARAAYMGNGTNGAYGCNAAYGAR GARGGNGTNGGNAARYTNATGTCNYTNGTNGARGAYYTNATGAARGAYATGMGNGAYYTN AARGARTCNCARCARACNYTNATGGAYAARGTNTCNAAYATHAAYYTNGAYGAYATHTAY AARMGNYTNAAYGAYATGGAYAARYTNTTYAARGCNYTNGARGAYAARTAYAARAARYTN GAYACNAARATGGGNACNYTNCCNACNTTYGAYGAYGTNGAYCARTAYYTNTCNCARTTY GTNACNTGGCCNGGNYTNGARGAYGCNYTNAARGGNATHMGNYTNGAYTTYGARAAYATG CARCCNGTNAGYGCNGARMGNGTNGTNATHGARYTNGGNACNCARACNGARACNCCNAGY MGNCCNCCNTCNGGNMGNCCNGCNTCNMGNGCNTCNTCNGTNCAYAGYAGYGGNCCNAGY AAYGARYTNYTNGAYYTNYTNGARMGNYTNGGNAARYTNGCNAGYGCNCAYGARGARYTN CARAAYMGNGTNGCNGARYTNGARMGNYTNATGGGNACNAARGCNGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGTTYAARAAR CCNAARTCNAARGTNYTNCARAAYGGNAGYGGNGARTCNGTNGAYAGYCARGCNAGY--- GCN------AGYAAYGARAAYYTNTCNTCNAGYACNAARGARAAYAARGAYACNGTNGAY AARATHYTNCAYCARMGNGTNCAYTTYCARGTNTAYTAYYTNGGNYTNGTNCCNGAYATH AAYYTNACNAAYTCNAARAARMGNGAYACNGARGCNCARYTNATHGAYGTNGTNGARGAR AAYCARATHGARGGNAARYTNCARGTNACNGCNACNGAYGARAAYAARGTNGTNATGAAY ATHTCNMGNCAYGGNATHAARGTNYTNGAYATHGCNGGNAARGARGTNYTNCARMGNCAY CCNYTNCAYACNATHGCNCARYTNACNGARTAYAAYGAYGGNTTYAGYMGNCARAAYATH GCNGTNAARATHGGNCARGTNGGNAARAAYGTNTAYCARTGYTAYGTNTTYCARTGYCAY TCNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARGGNGTNGGNACN GCNATHACNGCNACNGCNMGNGGNCAYAAYGARTTYAARAAYTGGYTNACNTAYGCNYTN ATHGCNGTNGTNATHGTNTGYATHYTNYTNCARYTNAAYTAYYTNAAYAARGCNYTNGAY ACNTTYAAYACNGCNGTNGTNACNCCNATHTAYTAYGTNTTYTTYACNTCNTGYGTNATH YTNGGNTCNGCNATHYTNTTYAARGARTTYTTYAARATGTAYGCNATG------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGNMGNGARAARCARATHGCNTAYGGNAARAGYACN GARTCNTAYAARYTNTAYATHAARACNGTNCCNAARGCNGARMGNTCNGTNGAYMGNAAR AARCAYCCNMGNACNCCNATHAARACNAGYMGNTGY------------------------ ------------------------------------------TCNCCNATHGGNGCNGAR ACNAARCCNYTNGCNACNGCNACNTCNGCNACNTCNYTNATHCCNACNTCNYTNACNAAY YTNTCNGCNAAYTCNATGAARCCNAGYMGNTCNAARCCNTCNACNCCNGCNACNACNATH AARCCNTGYGTNTTYCCNYTNACNGARGCNGARTCNGTNTGYCAYGARGTNGAYATGTCN GAYATHATHATHCCNCCNCCNATHAARACNGARGAYGTNCCNYTNCCNCCNGGNAGYCCN AARACNCCNGCNGGNGAYCARGTNAARYTNGAYAGYCARGTNGTNGARGAYYTNACNAGY ATHYTNYTNCCNGAYAAYCCNCCNCCNYTNGGNAARAGYTCNTCNAARGAYATHATGGAR YTNGGNAARGCNAGYGTNTCNTTYTCNTTYCAYAARACNACNAAYAARATHGCNACNACN TCNGCNTTYAAYCARGARGARCCNGAYCCNGTNGARGTNCCNCCNACNMGNCCNYTNACN YTNATGGAYAGYATHGARGARGARAARMGNYTNATGGARCARGARTCNCARCARAAYTCN GARGCNACNACNGAYAARAARCCNGARGTNCCNACN------------------------ ------------------------------AARCCNMGNYTNYTNGARAARTTYGTNCAR GTNGTNYTN---AARGARGGNACNGGNGARATHCCNTGGCCNGTNGARACNATHAARTAY ACNAGYACNCARCCNAGYATHCAYTTYGCNTGYAAYYTNATGCARTTYGAYTTYAARGAY ATHATGAARATHGGN---------------ACNACNACNGCNGCNGGNGAYGCNGCNGTN AARAARGGNGGNGARGARGTNAARGGNGAR------AARGAYAGYAARGARGGNAARGAR AARAARAARCAYTCNTCNMGNAARAARMGNAARMGNAARAARGGNAGYGGNAARGGNGCN GAYAGYAARAGYGCNGARGGNACNAARGTNGARAAR------GARGGNGGNAAYGARGCN ATGGARGGNGARAAYAARAARGAYAARAARAARAARMGNAARAARMGNAARAARGGNAAR CAYMGNCAYAARAGYAARAARGARGARGGNGARGCNGGNGGNGAYGCNAARGARGCNGGN GGNGAYGGNAARGGNGARGAYAARGAYAARMGNMGNTCNCAYMGNAARMGNACNCAYAAR GARMGNGAYGARAARGCNTCNGARAARGTNACNGCNGGNYTNGGNAARGARGGNGARGAR GAYGTNYTNGTNAAYGGNAARAAR---------AARGARYTNTCNTCNTCNACNGGNAAR MGNAARCAYAARMGNAARCAYMGNMGNMGNMGNCAYGAYMGNTCNGARAARGCNAARGCN ATGAGY------------GCNTCNGARAARAARACNGTNGAYACNGTNAAYGCNAARGAR CCNAARGTNAARATHGAYTAYGAYGAYGARGARGARACNCAYATHCCNACNGAYAAYGAR CARGAR---ACNGCNGARCCNAARATHAARMGNCCNTGYMGNTCNMGNAARMGNCAYMGN MGNAAYAGYAGYCAYAARAGYGARATGACNGAYTCNYTNAARTCNGARGAYCARAGYGGN GCNGAYCARYTNAAYATHACNTTYAARACNCAYAARAARATGCARGARAAYGCNATHAGY AAYYTNCCNGAYATHGTNAARGGNGTNAGYGCNGGNACNAAYAARYTNACNGGNCCNTCN AARGARAAYGAYACNCARCAYTCNAARACNCCNAAYGGNGAYATHAGYGGNTGYMGNAAR MGNGGNACNAGYATHTCNAGYACNGAYGGNACNACNCCNGCNAARGTNAGYAARGTNGAY AGYAARGCNGTNGARGARGAYACNTGGAGYAARATGGARGGNYTNTAYGARGAYATGGGN GARGARGGNTCNAARAGYAARTGGGAYACNAGYGAYAGYGARGGNGARGAYGCNYTNCAR AARACNYTNGAYGCNAAYGCNAARGCNAGYAGYAGYGGNAAYACNAARCAYMGNGARYTN ---YTNCARAARCCNACNAAYGGNAARATHCCNYTNTCNAARTCNYTNYTNYTNACNAAY GGNATGYTNCAYACNYTNCCNACNAAYCAYAAYAAYCAYACNACNTCNAARMGNGAYAGY GCNGARAARGGNGGNGGNGTNGARGTNGAYGAYAARTCNAAY------------------ ---------------TCNACNCAYAARCARTCNTCNTCNGCNTCNCARMGNGARGGNMGN TCNGGNAARMGNGGNAGYMGNMGNTCNTAYACNTCNTCNGARTAYTCNTCNCAYTCNMGN TCNTAYTCNMGNTCNMGNTCNGGNTCNTAYMGNAGYTAYTCNGAYGAYTCNMGNTAYAGY GAYTCNAGYMGNTCNCAYAGYMGNTCNTCNMGNAGYTAYAGYMGNAGYMGNTCNMGNCAY MGNTAYMGNMGNMGNTCNTCNTCNAGYMGNGGNMGNAGYMGNAGYTAYAGYTAYAGYAGY MGNAGYAGYTCNAGYMGNTTYMGNTCNMGNTCNTAYTCNMGNTCNMGNAGYTAYTCNMGN TCNMGNTCNMGNGGNMGNGGNTAYCAY---AGYAAYTCNMGNAGYCCNTCNMGNMGNAGY AGYGTNAARYTNAARMGNATHYTNAARTCNCCNYTNGCNATHGTNCCNGTNACNACNYTN ACNGTNGCNCCNGTNACNGGNTGYACNGTNGGNGGNGTNAARGAYAGYGCNACNACNAGY GGNGGNGGNGGNGGNGARGGNAGYGGNGGNGCNACNCCNGAYGAYATHCCNYTNCCNGCN AARGAYTCNTCNTCNGCNTCNACNTCNGCNACNAGYCCNAARAARGAYGARGAYAARTCN GTNYTNACNGAYATHCCNYTNCCNACNACNAGYAARYTNACNACNGCNGAYGGNAARGAR AAYTCNAAYTCNGGNGAR---------------------------------------AGY TCNGCNGTNGTNAAYAAYAAYGGNGAYCCNACNACNTCNGCN---CCNGCNGTN------ ---GCNATHCCNTCNGAYCCNCAYGCNAAYGGNAAYGGNATGAAYCCNAAYACNGAYCCN YTNGGNAAYCCNATHMGNGAYGGNAAYATGACNGGNGARAAYAAYGGNGGNGAYATGCAY GGNTAYGAYCARGAYTCNTAYAAYCARATGGGNTAYGGNAAYCAYGAYTCNGCNTTYTGY GARGAYACNGGNTAYGAYAAYTTYGARTTYGAYGGNGGNGGNGAYTAYGAYCARCAYGGN GGNGGNTAYGAYGAYCAYCAYCARGAYTAYGAYTAYAAYCCNGAYCCNTAYCAYCAYCCN CCNYTNMGNCAYCARGGNCCNCCNCAYGGNCAYCAYATGMGNGGNCCNCCNCCNYTNGGN TAYMGNGGNCCNCAYCCNMGNATGTTYCCNCCNGAYATGMGNTTYGGNCCNCCNMGNCCN GGNATGGGNCCNCCNMGNATGMGNCCNCCNAAYGGNCCNATGGGNCCNCAYCCNCCNATG GGNCCNMGNGGNCCNMGNCCNCCNATGGGNYTNGGNGGNCCNATGGGNCCNCCNGGNATG MGNGGNCCNCCNCCNMGNGGNCCNCCNCCNMGNGGNCCNCCNGGNATGMGNGGNCCNCCN GGNATGCCNGGNCCNMGNGGNCCNCCNCCNMGNCCNGGNATGATGGGNCCNCCNCARGGN GGNCCNATGGGNCCNAAYGGNCCNMGNCCNMGNATGGGNYTNGGNCCNCCNMGNATGGGN CCNCCN---CCNGGNCARGGNCARGGNCCNATGCCNCCNCCNCCNGGNGGNCCNMGNAAY MGNATGCCNCCNCCNGGNCAYATGCARGGNCCNATGMGNGGNGARGGNCARCCNCCNCCN CARMGNCCNGGNATGCCNCCNCCNGTNMGNGGNCCNATGCCNCCNCAYATGMGNGGNCCN YTNCCNCCNAAYATGGCNCAYCCNCCNCCNAAYTTYAAYATGCCNCCNCCN--------- ------------TCNTCNTCNTCNGARGGNATHAARCCNCCNGARTCNATGGARCCNCCN CCNYTNCCNCCNCCNAARGCNCCNACNCCNCARCCNCCNCCNCCNCCNAARAARGARGAR GARAARAARGARGARATHAARCCNATGGTNCCNGAYATHCCNCCNGARCARGCNGARCAR TAYMGNAARYTNMGNGARAARGCNCARAARCAYGCNAARAARCARCARMGNAARGCNGAR CAYCARGCNAARGGNGARCCNGARAGYAGYGAYGAYGAYGAYGAYGARGARGTNGCNAAR AARAARGARGAYGCNGCNAARYTNGCNGCNGARCARAARGARATGGARGARGCNGCNYTN YTNGCNGCNCARGGNGGNGARAARGTNGCNGTNGARGARGGNGGNGCNATHYTNGTNCCN TCNCCNACNACNCCNYTNGCNGTNCARCARCARGCNGTNTAYATHCARCARCARCCNATH GCNGCNGCNGCNGCNGCNGCNCAYTCNCCNTAYGGNATHGTNTCNACNCCNCAYYTNGTN CAYGCNACNCAYCCNGCNYTNCARGCNGGNCAYCCNCAYGCNCAYGCNCAYGCNCAY--- ---GCNCAYGCNYTNCARCCNCARYTNGTNCARYTNCCNAAYGGNCARGTNGCNTAYGCN ACNCCNGCNMGNCCNCARTCNGTNCCNYTNCARGCNGGNGCNCCNGTNATHGCNATGTCN CAYCAYGCNCCNATGGCNGCNGCNTCNCCNTCNATGTCNCAYCARYTNYTNYTNCARTCN GGNGCNGTNCCNGGNCARGTNCARATGGCNCAYGCNGTNCCNGGNCCNCARTAYATGTCN CAYGTNATGGCNGCNCARGCNCARGCNCARGCNCARGCNCAYGCNCARGCNCARGCNCAR ATGCARGCNGCNCARGTNCARGCNGCNCAYATHCARGCNGCNCAYGCNCARGCNGCNCAR GCNCARGCNCARGCNCARGCNCARGCNCARGCNGCNCARYTNCAYGGNYTNGTNCCNGCN GGNATGCAYGCNGCNCARCARATGYTNCARAGYGGNCARCCNGGNCARCCNCARGGNCAR ATHATHYTNGTNCCNMGNATHGCNMGNCCNCAYATG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNAARTTYAARGARAAYAAR AAYATGGAYAGYGTNGAYGCNTTYTGGGARATHTGYAAYCARGGNMGNAGYTTYATHGCN ACNAARCAYTTYAGYGGNTAYTTYTGYACNACNTGYGARAGYAARTCNAARYTNCCNTCN ATHTAYGCNMGNGTNTTYGGNTCNCAYATHCARATHAARTCNAGYMGNMGNGARGTNMGN YTNATHYTNTAYYTNTGGGAYMGNMGNYTNAAYATHAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARAGYAGYYTNGARMGNCARMGNAGYAGYAARYTNAARCARYTNCAYGAYCAYGCNAAY AARYTNMGNCAYGARGTNAARYTNYTNGAYYTNGAYMGNCARMGNCAYACNGTNGARGTN MGNAARMGNYTNGARCCNGARAARGAYTAYAGYTAYGAYGARGTNCARATHCAYAAYACN GARMGNMGNYTNGGNGCNAAYATHGCNTCNTTYTAYYTNGAYAARAARYTNAARTAYCCN ATGMGNYTNMGNTCNATGAARGAYATHMGNGTNACNCCNACNATHTCNAARGCNMGNGCN AARATHMGNACNAGYGAYGTNAAYAARGCNYTNGARGARGARATHAGYTTYTCNMGNCAR GAYMGNGCNCARACNGCNAARACNTCNTCNATHGGNCAYACNAAYACNAAYAGYGCNTTY MGNMGNMGNGGNTCNMGNTCNGCNCCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TTYGTNATHAGYTTYYTNCCNCAYYTNATHYTNAARTGYYTNCARGCNATHAAR AARGAYTTYCCNGCNAAYTCNGAYACNTCNGAYATHATHYTNTAYAAYATHTTYGTNMGN TCNTAYTTYTTYAAYAGYGTNGCNAAYTGYTTYATHTAYGGNTTYTGYAGYCCNCCNTTY MGNAARGARATHAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GAYGAYGAYCCNAAYGTNMGNGCNGTNGCNGCNATHGCNYTNGCNCAYGCNGGNAAR AARAGYGARTCNACNGTNGAYAARATHATHAARYTNYTNGARGAYGARGAYMGNYTNGTN MGNGARAGYGCNTGYYTNAGYYTNGGNTAYYTNMGNTCNACNMGNGCNGTNYTNCAYGTN GTNGAYMGNTGGMGNAAYGAYCCNATHTCN---------------ACN---GTNMGNGAY GCNGCNGARYTNGCNYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHGAR GAYATHGARAARATGATHGARMGNTGYGARMGNAARATHGAYGARYTNGARMGNAARAAY MGNYTNGTNGARATGTCNGAYGARCARTGGCARGARYTNAARAGYGARAARAARYTNYTN GARAARCARATHAARAARTAYAARAGYGARYTNMGNGGNYTNMGNTGGCARAAYTGGAAR AGYATGGTNATGTCNGTNTGYATHTTYGGNYTNYTNTAYGTNGTNTAYGTNGTNGTNTTY GAYTCNGARTCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CARATHGTNCCNTCNTTYACNGTNTCNAGYCARAARTCN GARTGYAGYCCNGTNAARYTNGARCCNGTNTCNCCNGAR---------------TTYACN TCNAARMGNGAYTGYYTNAARMGNTCNTCNACNGARGAYAARTAY------------GAR GAYTGGAARCARCCNAARMGNMGNMGNTGYGAYTCNGGNAGYTCNGGNATHACNTCNGAR GAY---GGNGAYTGYGAY------------GAYAAYGAYAAYTAYTAYGAYAGYGAYGAY GAYAAYTCNGAYYTNGAYGCNGAYYTNGCNCAYATGAARCCNGGNGGNTGYGARTCNYTN ATHGGNGGNGGNAARAARCARAARCARTAYTTYTGGCARTAYAAYGTNCARGCNAARGGN CCNAARGGNACNMGNYTNAARYTNGCNGTNGARTCNCCNGCNGAYCCNCAYGTNYTNAAY GGNTTYGARGAYCCNGTNTTYGAYGARGGNAAYACNACNGTNGCNGGNATHMGNCAYGGN GGNAARGCNMGNAARGGNGAYGGNAAYGARGTNAGYCCNAAYCCNCAYAARYTNTTYAAR ATHGGNCAYCARYTNYTNMGNYTNAAYAARAARATHAAYGGNTGYCARYTNGGNTCNGAY GTNCCNYTNGCNCARMGNAAYGARGCNMGNAARGARAARAAYAARYTNGCNTCNMGNGCN TGYMGNYTNAARAARAARGCNCARCAYGARGCNAAYAARATHAARYTNAAYGGNYTNGAR ATGGARCAYGGNCARATHAAYAAYGTNYTNMGNYTNYTNTGGCCNGARYTNMGNGARMGN GCNAARTGYYTNCARAAYGARCAYCAYGTNGARGAR------------AARCCNYTNCAR GAYAAYYTNTTYAAYAARYTNAAYGGNTAYATHACNTCNAAYATGAARAGYATGGTNGCN GGNCAYACNACNGAYTAYGTNAAYAAYGTNATHATGAAYGTNGARAAYGGNGAYYTNACN GGNGGNYTNAARAGY---AARGCNMGNAARACN--------------------------- ------------------------------------MGNMGNTCNACNGTNATHAGYGTN AGYGAYGARGGNACNGCNGTNGGNMGNGARYTNGARCCNGCNYTNGCNTAYAARGTNGAR AARGTNMGNMGNTCNGCNMGNGCNTCNMGNATHYTNAAYGARYTNGTNATHGARAARGTN GAYGGNGARAARAGYTTYTTYGARGTNTCNATHGAYGARTCNATGAARGGNAAYGGNAGY MGNAAYAAYTCNATHTGYAAYAGYCCNTCNAGYGTNAARTCNAAYAAYACNTCNCCNTTY ACNCCNMGNAARTCNAAYGARGTNACNGCNTCNAGYAAYAGYGCNACNTCNACNCCNYTN ACN---------------ACNTCNGCNGTNMGNACNMGNCAYTCNATGGCNCCNTCNTCN GCNTTYAARGARCCNGGNYTNCCNYTNTCNGCNYTNMGNCCNGCNGGNTCNCARMGNMGN AARACNTAYTGYACNCCNAARTCNAARACNCCNGARCARATGATHAGYATHYTNAARAAR AGYCCNATGGTNGARATGTCNMGNMGNAARTCNMGNCAYATGTCNTCNCCN------GCN CCNAARGGNCARTAYTTYMGNGAYYTNATHACNAAYGARACNGARMGNYTNACNATHYTN TCNGAYAARTGGAAYGGNATHGCNGCNATGGARGTNGGNYTNTCNGARGARGTNYTNGGN CARATHMGNTCNACNGTNGGNAARGCNYTNYTNYTNATGAARCARMGNTTYAARCARTTY TCNGGNYTNGTNGAYAAYTAYGTNTAYGAYYTNGGNGARAARAARACNACNCCNACNGAY YTNCARGGNTTYTGGGAYATGATHTAYTTYCARGTNGARGAYGTNAAYAAYCARTTYAAR GAYYTNGAYGARYTNCARCARYTNGGNTGGCARATHAARACNAAYACNCCNAARGCNGAY MGNYTNAAYYTNAARAARAARATHGTNAARGGNAARCCNAARGCNAARGGNGTN------ ------AARTCNAAYTTYGCNGCNTTYMGNGCNGARYTNCARAARAARAARGCN------ ------------------GARGAYYTNAARAARATGAARGTNCCNGARYTNAARCARGCN YTNAARGARAARGGNYTNTCNACNTCNGGNGCNAARACNGAYYTNATHAARMGNYTNGTN GARTCNGTNGARGCNTCNGGNGAYAGYAAY---GAYCCNGTNYTNGAYGAR--------- ------GAYGARATHYTNAARGAYGAYTCNACNCCNGTNGTNGCNGCNCCNACNACNACN GCNCCNAARGCNCCNGCNGARAARTCNGAR------------------------------ ------------ACNGCNAGYAAYGGNGTNGTNTCNACNAAYYTNGARCCNACNCCNAAY GTNAARATGGCNGCNGAYACNACNGTNGCNGCNAARCCNACNGARGTNAARAARATGACN GAYGCNGARMGNYTNAARYTNMGNGCNGAYAARTTYGGNGCNTCNTCNGARCARGCNAAR AARNNNYTNMGNGCNCARMGNTTYGGNATHGCNYTNTCNGARAAYAARTCNGGNAAYATH AGYTCNTCNACNGGNCCNGTNGAYGTNGARAARYTNAARAARMGNGCNGARMGNTTYGGN GTN------------TCNACNAGYTCNGTNACNGARGAYGARAARAARMGNAARMGNGCN GARMGNTTYAAYACNAGYYTNACNACNTCNACNTCNTCNAARAGYGTNAGYYTNAAYTCN ACNGAYAGYGARYTNGARGCNAARAARMGNAARMGNGCNGARMGNTTYGGNYTNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CCNYTNYTNCAYTCNAARATHACNGCN GCNAGYATHGARAAYGGNGCNGCNTTYGARGAYTTYGARGARCARYTNYTNGARTGGATG MGNAAYATGAAYTAYACNTCNGARGTNCARCARATHAAYATGTTYAGYTGYGARATHTCN CCNGGNTTYTTYATHACNCCNGCNTTYTCNGARYTNTTYCCNYTNYTNCCNTCNGAYYTN CARCARATHAAYTAYCAR---CARGGNATHMGNYTNGTNAARGAYGGNAARAAYTGYGAY GGNYTNAAYGAYGTNGARATHACNAAYYTNCCNGARGAYYTNGARATHCARATHMGNATG TTYTCNACNTCNYTNGAYGGNYTNYTNCARTCNATGAAYGTNAARGARGARATHTAYTCN ATHGGNTGYYTNAGYMGNATHATHGCNACNGAYYTNGAYAGYTTYCCNCCNGCNAARGTN MGNMGNAARACNTGYCARTCNMGNATGTCNYTNYTNYTNATHGAYMGNAGYYTNGAYYTN GCNACNGGNGTNACNMGNCARGCNGAYGTNYTNYTNGAYAARATHTTYAAYGTNYTNCCN TCNYTNGGNAGYAAYGAYTCNGAYAARYTNGTNGAYATGACNGAYYTNTGYCAYTGYTAY AAYACNAARTCNAGYCARAGYGTNATHYTNCCNGGNTGYYTNGCNCCNTCNAARATHAAR GARTCNTCNACNCAYYTNACNGCNACNATHATGAARAARCAYAARGARGCNYTNATGGAY ATHAAYMGNMGNYTNGTNGARACNGCNATGTCNGARAARYTNCCNYTNGAYYTNTCNMGN MGNCCNAGYMGNGTNACNGCNGAYYTNYTNGAYTCNACNYTNTCNYTNTTYAARGGNAAR TAYTCNYTNATHCARAARCAYYTNGAYACNYTNCARGTNGCNATGGCNACNAGYCARGCN YTNAARCAYCCNTCNGCNCCNCAYCAYGAYGGNGTNATHGCNAARGARAARAAYTTYYTN CARGCNATHGCN------------------------GAYGGNGARGARGARGGNGARAGY AGYGCNTAYCCNTCNGCNTTYTCNYTNYTNTCNAARYTNTTYATHACNGARYTNGGNMGN GAYAARGARGARMGNGARTTYACNYTNGAYGAYATHYTNCAYYTNYTNGTNTAYATHTAY TCNATGTCNGAYGGNAGYAGYGARAAYCARGARGARGTNMGNGTNYTNCARGAYTAYATH GTNCARYTNATHATHAARGAYAARGARTGYYTNCCNCCNATHATGAARGCNATHGTNGGN GAYAARGTNACNGARTCNATHYTNCCNGAYCARATHGARAGYATGTGGGARAARYTNGAY GGNYTNATGGARGTNMGNMGNGAYATGACNGAYTTYGGNAAYYTNYTNGAYCCNGGNGGN GAYATGAGYCCNGCNTCNGTNAAYCCNYTNYTNAARCARGTNATGGARMGNATHGTNGAY CCNGCNMGNCCNGARATGCCNGAYGTNGARTGYAARTCNGGNGGNYTNAARGAYYTNYTN AARTCNGGNTTYGGNTTYTTYAARAGYACNGCNAARCCNMGNCCNGGNGAYGCNCCNYTN YTNATGGTNATGGTNATHGGNGGNGTNACNGGNTCNGARGTNAARATGATHAARGAYATG GTNAGYAGYGCNAARCCNGGNTTYGARGTNATHATHGGNGGNACNMGNATHAAYAGYACN GARTCNACNYTNCAYTCNYTNYTNGTNGARGAYAAYATHAAYATHAAYATGYTNMGNGCN GCNYTNAARACNAGYGAYTGGATHAARYTNGAYACNTGGGARAGYGARCARAGYTCNTGG ACNGARACNGCNAARGTNYTNMGNCAYTTYAARCARYTNGTNGAYGGNCARTAYYTNTCN AAYGTNAARCCNTCNCCNAARAARMGNAARAARCARCAR---GTNTCNGAYYTNGCNCAY AAYAARYTNCCNAARGTNGAYGTNGARGARGAYCARGTNCCNAAYGTNMGNTTYYTNTGY GGNGCNGAYYTNYTNGARTCNTTYTCNGTNCCNGGNYTNTGGGCNGAYGAYGAYATHGAR GCNATHGTNAARAAYCAYGGNYTNGTNGTNATHAAYMGNGARGGNTCNAAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GAYATHTCNTAYGTNATGGCNAARGTNACNTTYGCNAARMGNTGYYTNCARYTNAARMGN TAYCCNGARGCNGCNGARCARTAYTCNAGYYTNATHGGNATGYTNYTNCARGARGAYATG TTYYTNCARTTYGARAARCAYGARATHAAYCARGARYTNAAYATHGCNGARATHATHGTN GARGCNGCNGARGTNYTNATGATHACNMGNCARTAYCARGAYTGYATHMGNYTNTGYGAY AAYACNCARCCNTCNYTNTCNGCNGAYGAYACNATHGCNACNAAYAGYCARTCNYTNACN AAY------------------------------GTNATHTCNCCNGARAAYTCNCARTCN GAYATHTTY---------------CAYYTNYTNGAYCARTCNCAR------AAYYTNGAR AAYTCNGAYCCNYTNTCNTGYCCNAGYAAR------MGNYTNATHTCNCCNAARGGNGGN AAY------CAYTCNTCNGCNGAYYTNTCNATHTCNTTYGARAARTCNMGNAARMGNGTN MGNTCN------------GGNGAYYTNYTNGAYAARGARGGNAAYMGNGARGAYGTNAAY GARGARAAYAGYAAYGAYATHYTNATGACNMGNYTNYTNYTNAGYAARGCNGAYGCNYTN GTNYTNTCNCARGGNTTYACNGAYGAYGCNATHTAYTGYYTNCARAARTGYATGGAYATH YTNATHCAYCAYCCNYTNTCNATHCAYAARYTNTCNTAYCCNACNCAYCCNCCNTAYTCN AARMGNCARMGNATHAGYTCNGAYGGNACNGCNGTNTGYCCNCARGGNYTNGAYAAYGGN CCNTCNGGNTTYTCNGARGCNTCNAGYAGYTGGTCNMGNYTNYTNGTNGAYACNGCNYTN MGNATGGCNACNGCNTCNTAYAARMGNAARMGNTTYTCNTCNGTNATHAAYAGYTGYMGN GTNGTNGARCARYTNGAYMGNGGNAAYATHGTNGCNGCNTAYYTNTGYMGNGAYCAYAAY YTNCARGAYGGNGTNCAYCCNCAYCCNTTYGARAAYMGNAARTTYATHGTNTGYGCNTAY CCNATGACNTCNGTNMGNAARTGYCCNTCNGGNTTYCARTAYGAYGCNMGNTCNATGGTN TAYAGYGCNACNCCNTGYAGYMGNCARGGNGCNMGNTTYCCNTCNATH------ATHGGN GTNCARACNYTNTGYAARGAYTAYGGNTTYTCNAAYGGNAARTAYCCNCAYCCNTTYYTN TGYGAYAARTAYATHCARTGYAGYAAYGGNYTNACNTAYGARATGCCNTGYGCNCCNGGN ACNAARTAYGAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNYTNYTNTGGTCNCAYAGYAAYAAR TTYYTNAAYCARTTYCARGCNAAYYTNCCNYTNTGYCARTAYMGNCCNTTYAGYYTNTTY CCNATGAARTTYGTNCAYGAYYTNAGYTTYTGGGARMGNGAYTCNGTN---ACNGTNTTY GAYGTNYTNGGNYTNTAYGARGCNATHMGNAGYGTNGTNGGNGAYYTNGTNACNAGYGTN TCNYTNATHGAYATHTAYGARGAYAARGARATGAARMGNMGNAGYMGNTGYTAYMGNYTN CAYTTYYTNTCNTCNGAYAARTGYYTNTCNTAYGTNACNTCNTGGAARATGCARAGYAAR ATHMGNATGGARGTNGCNMGNAGYYTNGGNGTNCARYTNMGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNGTNYTNGCNATHTCNCARCAYCARAARYTNGAY GCNTAYGGNGARGGNTTYTAYATHGCNTGYGTNTGGTGYTTYATGACNTGGAARTGGGGN TTYYTNYTNYTNATHTAYTCNMGNACNTAYYTNMGNACNTAYATGAGYGARTCNGAYCCN ACNTCNTAYTCNCARCCNGARAARTGYGTNATGACNCARYTNGAYTGGAAYGTNAARYTN GAYTTYACNGCNCARACNATHAGYGGNGTNGCNAGYYTNTAYTTYGARAARAARGAYAGY AAYYTNGAYACNYTNYTNYTNGAYATHMGNGAYYTNAARATHGARAGYGTNAARYTNCAR GARAAYAAYCARAAYYTNACNTTYACNGTNGAYAAYCCNGTNAARGTNGARTTYGGNTCN MGNYTNTCNATHCARATHATGTCNGAYAARAGYAARAGYTTYGCNYTNGAYATHACNTAY AGYACNTCNAARAAYTCNACNGCNYTNTGYTGGATGACNCCNCARCARACNGCNGGNAAR MGNCARCCNTAYYTNTAYAGYCARTGYCARGCNATHCAYGCNMGNAGYYTNTAYCCNTGY CARGAYACNCCNGCNGTNAARTTYACNTAYAARGCNCARGTNGARGCNCCNAAYGARATH ACNGTNYTNATGAGYGCNAAYMGNGGNGARGTNGCNCCN------GGNTCNAARGGNCAY AGYATHACNAGYTTYTCNYTNGAYATHCCNATHCCNAGYTAYYTNYTNGCNATHGTNGCN GGNGAYYTNGARTCNMGNGAYATHGGNCCNMGNTCNAARGTNTGGTCNGARAARGARYTN GTNGAYMGNGCNGCNCAYGARTTYGCNGARACNGARTCNGCNYTNAARGCNGCNGARAGY YTNATGGGNCCNTAYGTNTGGGGNCARTAYGAYYTNYTNGTNYTNCCNCCNTCNTTYCCN TAYGGNGGNATGGARAAYCCNTGYYTNACNTTYGTNACNCCNACNYTNYTNGCNGGNGAY MGNTCNYTNGTNAGYGTNGTNGCNCAYGARATHTCNCAYAGYTGGACNGGNAAYYTNGTN ACNAAYGCNAAYTTYGARCAYTTYTGGYTNAAYGARGGNCAYACNGTNTTYTTYGARMGN AARATHCAYGGNAARYTNAAYGGNGARGCN---TGGAARCARTTYCAYGCNAAYGARGGN TGGATHCARYTNAARAARACNATHGAYGTNYTNACNTCNGAYGGNAARCCNGCNTAYACN AARYTNGTNCCNGAYYTNTGYGGNGTNGAYCCNGAYGAYGCNTTYTCNAARGTNCCNTAY GARAARGGNTCNGCNYTNYTNCARCAYYTNGARACNYTNYTNGGNGGNCCNGAYGTNTTY AAYGTNTTYYTNAARGCNTAYATHGARCAYTTYAARTAYAARTCNATHTAYACNAARGAY TGGAARGARTTYYTNTTYAARTAYTTYTCNTCNGAYGARGAYCARAARAARYTNGAYAGY GTNGAYTGGGAYGCNTGGYTNTAYGGNGARGGNGTNCCNCCNTTYAARCCNAAYTAYGAY CARAGYTTYGCNCARACNAGYYTNAAYYTNAGYGARMGNTGGATHAAYGCN------AGY AGYGCNGAYAARTTYGCNYTNGARGAYATHAARAAYATGAARGGNGAYYTNGTNAARGAR TTYGTNTCNMGNYTNYTNATGGCNGARCCNCAYATHTCNAARGAYAARGTNGARCARYTN GARTCNGTNTAYAAYTTYAAYGCNGTNAARAAYTCNGARATHCAYTTYACNTGGYTNGAR YTNTGYATHCARGCNCARTGGATHGAYTCNATHCCNCAYATHYTNAARTTYYTNAAYGAR CARGGNMGNATGAARTTYGTNATHCCNYTNTAYMGNTCNATGAAYAARTGGGARGCNGGN MGNAARCCNGCNYTNGARAAYTTYGARAARCAYAARGCNGARATGCAYAGYACNACNGTN AARAARGTNGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNGAYGCNYTNACNGCNTTYGGNAARAAYCCNAAYCCNCARGARATHCCNTCN GTNYTNGARCARTAYYTNAAYTCNGTNGCNAARAAYGGNGARACNYTNTTYCCNTGGACN CARYTNAARCCNYTNATHYTNMGNAARATGGARYTNGTNATHATGGARYTNMGNMGNAAY YTNGCNTCNGARAAYATHCCNACNMGNCCNAAYGTNGARAAYGTNMGNTTYGAYGTNATH CAYGCNMGNATHATHGAYTCNYTNCAYAARTTYAAYGGNGCNCCNTTYACNATHCARMGN YTNTGYGARYTNYTNATHGAYCCNAARMGNCAYTAYAARMGNAGYGAYAARTTYATGMGN GGNYTNGARAARAAYGTNYTNGTNGTNAGYACNGTNGAYCCNTTYGGNMGNAARGTNGTN TCNGARYTNGGNAAYAARCCNGTNYTNAAYGGNATHYTN---GAYATHAAYGGNTCN--- TAYCCNCCNMGNGAYTCNGCNYTNAGYGTNCCNYTNCCNCCNGTNCCNGGNTGGGTNAAY ACNTCNGCNGCNAAYMGNAAYGCNGGNACNGGNGTNATGTCNTCNTCNGCNGTNGAYGGN GGNAAYAARGCNGGNCAY---------------AAYATGGAYACNYTNGAYAARGAYTCN GAYGGNATGGTN------TCNAAYAGYATGGCNGTNGCNGGNACNCARCCNYTNGCNGTN CAYTCNGARGARGTNGTNGARGARACNGTNGTNACNATGGAYACNGGNGARGTNAGYTCN GTNGTNACNGAYGGNGGNGARGCNYTNGCNGAYMGNGAYATGGARGGNGGNGAYATHGAY MGNGARGAYMGNGAYGCNTCNTCNTCNTCNTCNTCNTCNTCNTCNTCNTCNGARGARYTN TCNACNTCNTCNGAYTCNGTNGARAAYAGYATGGCNACNGGNAAYMGNYTNAAYGARGAR GTNACNGCNATGGAYGARAAYMGNCCNTGGGCNGCNTTYGCNCARGAYATGAARCARCAR CARGAYGAYYTNGGN------ACNACNTCNYTNTCNTCNTCNTCNACNCARCCNGTNAAR GGNGARACNTCNGAYCCNTCNTCNYTNTCNTCNTCNTCNTCNTCNYTNTCNCCNACNCAR TCNTCNYTNCCNTCNGCNTCNAARACNACNTCNATHTCNACNTCNAAYGTNGARGARGAY MGNCARGARGAYAGYCCNGAYGAYGCNGARTGYGCNCCNACNAAYCARCARACNACNGTN TCNTCNGAYCARTCNGAYTGGCARCARCARCARTCNYTNTGYGAYGARCCNTCNTCNAAY GCN---------GAYGGNACNGAYCARAGYTTYGGNTTYGAYACN---ACNACNACNACN CCNACNCCNTCNTCNCCNCARCAYATHGCNGAYATGACNACNTCNGCNACN--------- ------------ACNGCNACNGAYAARYTNATHTCNTCNTCNACNAGYACNGTNATHTCN ACNGTNACNACNACNACNACNACNACNAAYAAYAAYAAYAARAAYACNTCNTCNTCNTCN GAYATHCAYACNTCNTCNCCNYTNACNGAYGGNGAYGGNGTNTCNGCNCCNCCNACNTAY GCNCAYGTN------------------GTNGCNTCNTCNACN------------ACNGAY AARACNTCNTCNTCNTCNGTNTCNTCNATHCARTCNAGYACNGARTGYGAYAGYGTNGCN GGNYTNGARMGNYTNGTNGGNTCNATGGARCARTCNYTNTCNTCNTCNTCNTCNYTNTCN TCNTCNTCNTCNTCNACNGCNTGYCCNTCNTCNACNTCNTCNTCNACNCCNTCNTCN--- ------ATHAGYGAYGTNTTYYTNCARGTNTTYGTNTTYATHGAYTAYGCNATHYTNTCN GGNATHATHTCNYTNTCNGGNYTNATHTCNAAYGTNATHAAYATHATHATHTTYTAYMGN YTNGGNTTYAAYGAYACNGTNAAYATHTCNYTNTTYAGYYTNGCNYTNTCNGAYYTNGGN GCNYTNYTNCCNYTNGTNTGGAARGCNATHYTNTTYAAYCCNTCNTTYCAYAAYTGGGAY ATHACNTTYGAYTAYATGACNTTYCARTAYTAYACNGGNGGNTGGCCNCAYGGNTGYTTY GCNAAYTTYTCNGGNYTNATHATGTTYTTYGTNACNYTNGAYMGNTGYYTNTGYATHTCN ATGCCNYTNAARGTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNAAYGAR CCNACNCCNACNGTNACNTGYACNCARGGNATHACNAAYGCNCCNATHATHCCNCCNGCN GCNCCNACNACNATHTCNYTNAAYCCNGCNCARGCNGCNYTNATGAARCAYGTNGCNTTY AAYCARCARGCNGTNAARGCNGARATHGGNGGN---GTNGCNGGNYTNTCNAAYAARMGN AAYTAYCCNATHCARYTNTCNYTNTCNYTNAGYCCNGCNGCNAAYGCNTCNTCNGGNATH CCNTCNACNYTNTCNACNCARTAYYTNGCNGCNTCNATHTCNACNGCNTCNATGGTNGCN CARMGNYTNAARACNCCN---CCNAGYCARCAYMGNTCNAGYTCNTCNCCNYTNTCNAGY CCNGTNGCNCARCCNAARGTNTCNACNCCNCARCARGGNACNAGYATHCCNYTNATHGCN YTNCCNAARGCNTCNACNCCNACNYTNACNCCNCCNCCNAAYTCNMGNACNCCNACNCCN ACNYTNGCNGGNTCNMGNMGNTCNTCNAAYGAYYTNTCNCARCARATGGCNGCNGGNGTN AGYAAYCARCARACNYTNCARCARCARAAYATHACNAAYTTYATHCARGGNYTN------ ---ACNGCNAGYGCNGGNACNGAYAAYCARAAYTCNGGNCARCARCARAGYAGYGGNGGN YTNGCNAAYYTNAGYATHAGYAAYYTNGGNCARYTNTCNTCNAAYYTNAAYYTNCARGGN YTNGCNGGNYTNTCNGGNGTNAAYATHACNAAYYTNAGYGGNYTNCARCARATGCARGTN TCNYTNGCNCARATHGCNGTNCCNATHACNATGATHAAYGCNAAYGCNAAYYTNYTNCAR ACNCARTCNGGNATHYTNACNAAYAGYTCNGCNACNACNGGNAGYTCNACNGCNACNYTN GTNACNATGGTNACNGCNYTNCCNGCNTCNTCNACNAAYACNACNACNACNACNAGYGTN ACNGGNTCNTCNCARGTNGCNGTNTCNACNGGNTCNAAYATGYTNTCNTTYCCNGTNGGN YTNAGYGGNYTNACNCARYTNATGCCNGTNACNTCNAARGGNCARGCNGGNCARACNATH MGNCCNACNGCNATGCCNYTNYTNCARYTNCARGGNCARCARGGNATHCARYTNYTNAGY YTNCARCARMGNGGNCARGTNAARCARGGNACNAGYAGYTCNAAYACNGCNCARGGNATH ACNMGNYTNGCNCARGCNGGNACNACNACNGTNCCNYTNTCNACNGTNYTNGCNGGNCCN CARATGACNGCNYTNGCNATGGGNAAYAARCARGGNCARGGNGGNAGYACNGCNATHACN GCNCARCARYTNATHCARYTNACNGGNGGNCARGGNGCNTCNYTNGGNCARGGNGCNGGN CARMGNGCNGCNCAYATHACNTTYGGNAARGGNCARCARGGNYTNCARTTYCAYTCNYTN CARYTNAARCARAGYGGNGCNACNYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYGAYGTNTAYGTNGGNGTNGAYGTNTTYGGNMGNGCNACN CCNGGNGGNGGNGGNTTYAAYTGYAAYCARGTNYTNGARYTNATHTCNAARGTNGGNYTN TCNTGYGCNATHTTYGCNCARGGNTGGGTNTAYGARAAYCAYGGNGCNGARCAYTTYGAY GAYAAYGARYTNAARTTYTGGAARYTNYTNAARGAYTTYYTNCCNMGNMGNACNCAYACN GTNCCNYTNAARACNTCNTTYTGYCARGGNTTYGGNCARAARCAYTAYYTNAAYGGNAAR GTNGTNAGYGARAARGCNTGGCAYAAYYTNTCNYTNCARCARYTNCARCCNTGYTAYGGN GAYAGY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNACNTCNAARGARGCNCCNTCNACNTCNAARGAY GTNCCN------------TCNACNTCNCCNTCN---TCNAARCCNCCNAARMGNAARAAY TCNGAYTCNGAYGARGAR---------GTNACNAARMGNTTYAARMGNCARGAYGARGAY MGNMGNAARATGCARGTNYTNGTNTCNAAYTTYTCNGARGARCARYTNAAYMGNTAYGAR ATGTAYMGNMGNGCNACNTTYCCNMGNCCNTCNGTNAARAARYTNATGCARAAYATHACN GGNTCNACNGTNTCNCARAAYGTNGTNATHGCNATGTCNGGNATHGCNAARGTNTTYGTN GGNGARGTNYTNGARACNGCNYTNGAYGTNAGYGARAARTGGGGNGAYTCNGGNCCNYTN CAYCCNAARCAYYTNMGNGARGCNGTNMGNATHYTNAAYGCNAARGGNATGATGCCNTCN ACNAARAAYAARAARTGYYTNTTYAGYACNATGTCNGCNYTNAGYMGNATHYTNGTNCCN TCNACNAAYCCNYTNGGNCARTGYCCNGCNTGGATHCAYGGNAAYGTNAARGAYGCNGCN AARGCNATHATHGTNATHCARGARTGGTGGGGNGTNAAYGAYTAYATHAARTCNACNACN CARCARATHGGNGARGAYATGAAR---TAYGTNACNGTNGTNCCNGAYYTNTAYMGNGGN AARGTNGGNACNGAYMGNGARACNGCNGGNCAYYTNATGGAYAAYYTNGAYTGGCCNGGN GCNGTNGARGAYATHGAYGCNTGYGCNAARTAYYTNAARAGYCARGGNATHAARAARGTN GGNGTNACNGGNTTYTGYATGGGNGGNGCNYTNTGYYTNGCNACNGCNGCNYTNAARTCN AGYGTNGAYGCNGCNGTNCCNTTYTAYGGNATHCCNAGYAARAARTTYTAYGAYGARAAR GAYATHMGNATHCCNYTNCARTGYCAYTTYGGNGARAARGAYGARGTNGTNGGNYTNTCN TCNCCNACNGARTAYGARGCNYTNMGNAARMGNYTNACNGARGTNAARGCNAAYTTYGAR TTYCAYGTNTAYGAYGCNGGNCAYGCNTTYGCNAAYCCNACNTCNCCNYTNTAYAAYGCN AAYGCNMGNGARYTNAGYTTYTCNMGNATGTAYAARTTYTTYGCNGARCAYYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNTCNCAYGCNYTNGAYTAYGGNTGGAAYACNTCNCAYTGYTGYCARGARATH TTYAGYACNYTNCAYATHGAYACNAARAAYGTNYTNTTYAGYCARAARAARCARGCNGTN CCNTTYTAYGCNTCNGGNYTNGGNATHYTNGARCCNATHMGNGGNGGNTCNCCNGCNGAY AARAGYCARCCNCCNGTNGCNCCNACNCCNACNYTNYTNGAYACNAGYAARCCNGARGAR GCN------AARAARTCNYTNGAYATHCCNCCNGTNGAYTTYGAYTGGGGNTCNAGYGGN YTNACNAAYCCNYTNAARGTNTTYAARAAYGAYAGYTTYAAYAAYGGNYTNTCNTCNYTN GARCCNTTYTCNGAYGTNYTNAARAAYATHGARCCNACNAARGAR---YTNAGYAAYGAR GCNAARAGYATHYTNTCNAARATHCCNAAYYTNAAYTTYATGMGNTCNAAYGTNYTNATG TTYCCNATHAAR---------TGGACNTCNGTNGCNAGYYTNYTNMGNAARGTNTCNCCN AGYGAYATHAGYAAYGTNTGYCAYYTNATHGCNGARAGYTTYTGYCARGAYAARGCNATH AARTCNGAYYTNYTNATHTCNTCNTGGTCNATHGARGARTGGTGGGAYGTNMGNGCNGCN YTNYTNGARYTNATGAARAARGTNGTNCAYCARGAYTGGACNMGNGARCARATHCAYGAR GARYTNGAYTCNGTNGAYGAYACNTTYAARACNACNATHTCNGARGCNATHACNGTNCAY MGNTAYTCNYTNAARAARAARYTNYTNCARAAYACNGCNTCNATHTCNCAYGCNGTNYTN YTNGAYTTYGAYTGGAARYTNCARYTNGCNYTNTCNAGYGAYAARATGTCNAGYYTNCAY CARCCNTTYGTNACNYTNGAYYTNGAYATHMGNCAYGCNAAYGGNGAYMGNAARGARGTN GCNYTNGARATGGAYAARGARGARYTNGCNMGNYTNATHTCNTCNYTNGARAGYTGYAGY AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNCAYGGNGGNCAYCAYGAYGGNAARCCNYTNGARTTYTCNTCNGAR ATHCAYAAYAARGAYCAYATHATHGARCAYYTNCARMGNCARATHTCNACNAARCCNAAR GAYCARATGACNGAYGARGARYTNGARTTYCAYTAYTTYAARYTNCAYGAYTAYGAYGAY AAYAAYAARYTNGAYGGNGTNGARATHGGNAARGCNYTNACNCAYTTYCAYGAYGARGAY ACNAAYTCNACNGCNGCN---------------------------GTNCCNGGNGTNACN GARGARGARYTNGCNGARGAYGTNGAYGARGTNYTNGARGAYAARGAYMGNAAYAARGAY GGNTAYYTNGAYTAYGTNGAR--------------------------------------- ------------------------------ATGGGNMGNGGNMGNTCNAGYGAYTCNGAY AGYGAYTAYTCNMGNTCNAARAARAARAARGARAARMGNMGNMGNTCNMGNAGYAARTCN TAYAGYTCNAGYGAYTCNAGYMGNCAYYTNAGYTCNAARAGYAARAARACNAARAARAGY MGNAARCAYTCNAGYMGNCCNCCNTCNGTNAGYCCNGAYMGNCAYMGNGGNTCNAARGAR MGNTCNMGNMGNTCNMGNTCNMGNTCNATHGARMGNMGNACNTCNMGNMGNTCNMGNTCN MGNTCNMGNTCNCCNTCNTCNMGNGAYMGNMGNMGNTCNMGNTCNGGNTCNCARMGNMGN TCNMGNTCNCARTCNGCNTCNMGNAGYTAYAAYAAYMGNAGYAAYAGYMGNMGNTCNMGN TCNGGNTCNMGNAGYMGNMGNTCNMGNTCNAGYTCNMGNGGNCAYGGNGGNAGYAGYMGN GTNAARAGYGAYMGNMGNMGNTCNMGNTCNAARTCNAGYTCNMGNGGNACNACNGAYMGN TCNMGNCAYGTNAGYCCNGARMGNTCNAARGTNGARCARAGYCARGGNATGATGTCNTCN TCNGARAARGCNGARATHMGNATGMGNAARGCNYTNCARGCNGCNGCNGCNGCNGAYGAR AARYTNAARACNYTNMGNGAYCARGCNYTNTCNYTNTCNMGNTCNTCNCCNTCNACNGAY AGYATGTCNGARYTNTCNYTNTCNATGACNGCNTCNMGNGAYTTYGTNGAYTCNGTNGCN GCNATHGAYGCNGAYMGNTTYGTNCARTCNTCNTTYAARTCNGGNGGNATHGTNGTNAAR GARGARYTNCCNGAYCCN---YTNATGTCNAGYCAYGAYGAYGCNATHTTYGGNTCNYTN TCNTCNGTNGGNTTYACNATHAARCCNGAYGTNGAYAGYAARCCNGTNGCNATGGAYGCN GAYTCNATHATGCAYCCNTCNYTNTAYTGYAAYGTNGARGAYAARATGGARMGNTGGATH GAYMGNYTNTCNCAYYTNMGNMGNMGNAARYTNGARGGNGARGCNATGATGGAYGTNGTN GTNGTNGGNAGYTGYATGACNGAYYTNATHAGYTAYGCNCCNCAYYTNCCNAARGARGGN GARACNYTNACNGGNTAYAARTTYTCNGTNGGNTTYGGNGGNAARGGNGCNAAYCARTGY ATHACNGCNGTNAAYYTNGGNGCNCARGTNGCNATGGTNGGNAARYTNGGNGAYGAYACN TTYGGNAARGAYTAYCARGTNAAYATGAARACNAAYAAYGTNAAYTGYGAYCAYYTNAAY ATHGTNCCNGGNGTNTCNAAYGGNGTNGCNTCNATHCARGTNGCNGAYAAYGGNGCNAAY TGYATHATHATHATHCCNGGNGCNAAYAGYCAYYTNACNGTNGARGAYGTNCAYAAYGCN GARGAYGTNATHAARAAYTGYMGNGTNYTNATHTGYCARAAYGARATHCCNCARGARATH TCNYTNTCNGCNGTNAARATHGCNAARAARCAYAAYGTNAARGTNATHTAYAAYCCNGCN CCNGCNTCNTCNAGYYTNYTNCCNGARYTNTTYTCNYTNCCNGAYTAYTTYTGYCCNAAY GARACNGARGCNGARATHYTNATHGGNAGYCCNATHAARACNGTNGARGAYGCNTTYGAR GCNTGYAARATHYTNCARAAYACNAARGGNTGYAARTCNGTNGTNATHACNYTNGGNGAR AARGGNGCNGTNYTNAARGAYATHTCNTCNAAYGARGCNGTNCAYGTNTCNACNTCNCCN GTNAARGCNGTNGAYACNACN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------ATGATG CARCCNCARATG---------CARATGCARTCNCARCAR---CARCARCAYATGAARCAR AAYCCNAARTTYGTNCCNCARGARATHCCNAARAGYGAYCCNAARGGNGARAARCCNCCN GTNACNACNGTNTTYGTNGGNAAYATHAGYGARMGNGCNCCNGAYATGATGATHAARCAR ATGYTNCARMGNTGYGGNAAYGTNYTNAGYTGGAARMGNGTNCARGGNGCNTCNGGNAAR YTNCARGCNTTYGGNTTYTGYGARTAYGARGAYCCNGARGCNACNYTNMGNTGYATHMGN YTNYTNAAYGAYTGGCCNATHTCNAAYAARMGNYTNGTNGTNAARGTNGAYGCNAARACN AARACNYTNYTNGAYGAYTAYAARAARAARAARCARGGNGTNGAR---GAYGGNATHAAR AARGARCCNGARACNGGNGARAARCARGARAARGGNGARGARGARAAYGGNGAYGAYAAR AARGARGARGGNGGNAARGARGARTCNGARGARAARGARGGN---CARYTNGAYGARAAY ACNCARMGNGARGAYMGNYTNGCNCARGCNGGNYTNGARGCNATHATGAARGARTAYGCN TTYGARYTNGCNAARGARCCNGCNAARTCNAGYGAYGGNGGNGAYCARGAYAARGARAAR CARATGCCNAARAARGARAARGARGTNTAYATGCAYGCNAARGAYACNGGNTTYGAYGAY ATGGARATGGARGAYGAYAARMGNGARATHATHAAYMGNGARATHAAYAARTTYMGNGAY MGNCAYAARGAYGAYGAYGARGARAARGARAARAAY---MGNGARAARGARMGNAGYYTN GCNMGNGARMGNGAYMGNMGNCARGARGARAARMGNCAYMGNGARMGNYTNGARAARYTN MGNGARCAR------------------------MGNGARMGNGARMGNGARMGNCCNCCN ACNMGNGTNTCNMGNTCNAARTCNMGNTCNGTNTCNCCNGTNCCNTCNMGNTCNMGNMGN MGNTCNMGNTCN------------MGNGARMGNACNAGYMGNGAYMGNTCNMGNGARMGN MGNAARGARMGNGARATHGARGARGARGARGARATHTAYGARMGNMGNAARYTNGARAAR AARYTNMGNGARAARGARGCNGCNTAYCARGARMGNYTNAARAAYTGGGARGGNMGNGAR MGNAARAARACNMGNGARTAYGARAARGARAAYGAYMGNGARGAYGARMGNAARGTNGAR GARGGNMGNGARGCNMGNMGNYTNAARGARTTYYTNGARGAYTAYGAYGAYYTNMGNGAY GAYCCNAARTTYTAYAARGGNAGYGCNYTNCARMGNMGNCARAARGARMGNGARAARGAR AARGARYTNGAYAAYMGNGAYMGNCARMGNGARAARGARGARTTYGARGARATHAARMGN AARYTNTTYGAYGARGGNCAYCCNGAYGCNGARACNGARGTNGCNMGNATGGARMGNGAR MGNGARGARCAYYTNCARCCNMGNYTNCAYYTNCARGARYTNAARCARCCNCCNCARCCN GTNGTNAAYGARGARTCNGAYTCNGAYAAYGARCCNCCNCCNTCNAGYAARGCNGARCCN MGN------CARCCNCCNTCNCCNAARCARTCNGAYCAYCAYCCNCARTCNMGNAAYGGN CCNAAYAGYCARCARCARCAYCARYTNATHCCNGARCARCARCARCARCARCCNCARMGN CCNTCNCCNTCNYTNTCNACNTCNCCNATHTCNACNGAYTCNMGNGTNAGYAGYGCNCCN GGNYTNTGYATGGAYGARTCNTCNCARTCNTCNTTYCCNCCNACNGCNCCNCCNYTNATG TCNTCNTCNTCNTAYGGNGARCCNMGNYTNGGNAAYAARCAYTCNACNACNTCNACNTCN TTYAAYAAYYTNGCNCCNGGNATHAGYCCNGAYTCNTCNAGYYTNCCNGGNGTNGTNACN ATHTCNGAYGGNAARMGNAARAARYTNACNGTNGGNGAYGTNTTYAAYCARGAYGAYGAY GAYAGYAAYGARCCNAARAARMGNAARYTNATHCCNYTNGAYTAYGAYGARGAYAARACN ACNCCNACNGARAARAARGGNGCNACNGCNGARGARAARMGNCARNNNATHAARCARYTN ATHGARAAYATHCCNACNGCNAARGAYGARYTNTAYGCNTAYACNGTNGAYTGGGAYATH GTNGAYCARGCNYTNATGGAYAARMGNATHAARCCNTGGGTNACNAARAARATHGTNGAR TAYATHGGNGARGARGARCCNACNYTNACNGARTTYATHTGYCARAARGTNATHGCNMGN AGYACNCCNCARAGYATHCARAAYGAYGTNGCNATGATHYTNGAYGARGARGCNGARGTN TTYGTNGTNAARATGTGGMGNYTNYTNGTNTAYGARACNGARGCNAARAARYTNGGNYTN GTNAARYTNGTNACNGARGARTAYAAYAARCARGCNGCNGAR---TGGCCNCARGARGGN AARCAYATHYTNGCNCAYTAYAAYGAYGARACNGTNGTNGTNTAYCARGCNTAYAAYTCN MGNATHGCNGAYTAYGCNGTNAARTAYCARAARTTYGGNGGNCCNGAYTTYAARTAYGAR MGNATGTCNTGGATHAARCCNAAYTTYATGTGGATGATGTAYMGNTGYGGNTGGGCNCAR AARAARGAYCARGARMGNGTNYTNGCNGTNTGGYTNACNAARCARGGNTTYGARAAYATH YTNGCNGTNGCN------------AARACNGGNMGNGARAGYGAYTCNMGNAARACNGAY GARGTNMGNATHCARTGGGAYCCNGAYCAYGGNCCNCAYGGNAAY---ATHYTNCCNMGN MGNGCNATHCARYTNGGNYTNMGNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TTYYTNGCNAAYGTNAARGCNMGNTCNYTNGCNACNMGN TCNCARGTNAARAAYGGNTCNGGNGAYGGNCAYAGYTCNAGYAGYAGYAAYGCNCAYACN AARGCNAGYTCNYTNGAYATGGARTGGGARCAYGARGCNGGNATGTCNCCNAAYAARMGN CCNAAYCCNATHTCNGTNTCNGARGAYAAYTGGTCNAARACNTCNACNGCNAGYCCNYTN CAYTCNAGYGAYYTNGARTGGGAYCCNGAYTTYGTNTCNGCNGAYGAYAAYGARMGNCAY CARYTNYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNACNTAYAARGGNTCNYTNGARACNAARGARTAYATHATG GAYGARGTNGCNAARTGYATGAAYYTNAAYCCNAAYMGNTTYTGYGTNTTYGCNGCNYTN YTNGGNAAYCAYATHYTNACNGAYGARGAYYTNGTNCCNTTYMGNGARAGYYTNCCNGCN CCNGAYAGYGGNAARCCNMGNMGNCCNMGNGAYCARYTNGAYGCNTCNATGATHAARGCN ACNTGYGAYTAYGTNMGNAAYYTNCARTCNGTNGARAAYTGGGAYGGNGTNGGNAAYGAY GTNTTYAARYTNGCNAARAAYAAYAARACNGAYYTNGTNGARMGNTTYAARAARAGYGTN AARTAYTAYGTNAGYGGNACNCARGARGGNTAYTTYAARTAYGTNYTNAAYMGNGGNCCN YTNATGTCNCARCCNATGTAYGGNCCNCAYACNCAYAAYGAYMGNAARCARGGNAAYTCN MGNGGNAGYGGNAAYGCN---------------------MGNAGYTCNGGNYTNCCNCCN GTNTCNCCNGARATHATGMGNGTNGCNATHGAYMGNCAYCARAARGGNYTNATGCAYCCN YTNATHTAYCARGTNYTNACNCARGGNGARGTNAARYTNCCNGTNATHYTNGARGAYGAR ACNCCNMGNGARYTNCCNAGYTAYATHGAYTGYTAYMGNCCNATHMGNGARACNATHTAY TCNGTNYTNYTNAAYYTNAAYAARCARAARATHGTNCAYGARATGCARAAYAARGARAAR CCNTCNAAYAARTTYCCNGAYTTYACNGCNCARGTNAARGARTGGGTNGTNMGNMGNCAR TCNGGNMGNGCNGCNTAYGARGTNGTNACNGCNMGNCCNGTNGARTGGAARGCNCCNAGY GTNCAYMGNATGTGG--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATHYTNCAY AARGCNGARYTNATHMGNGARCARAARTTYGGNTCNAGYGGNCARACNCARAARACNTCN AARAAYGARGAYGCNAARAARMGNGCNAARGTNACNAARAARAAYGTNAAYGCNACNGCN GTNTCNACNAARCARACNCCNGAYAGYGARAGYAARTCNGARAARAARGAYGARGCNCAR GCNACN------------------------------------------------------ GCNAGYGTNAARCCNGCNAGYTCNAGYAGYCARGGNATGTTYGGNGGNATGAARAARGGN TTYYTNTTYGGNGGNTCNAGYAARCARCCNAARYTNTCNTCNAAYACNTGYGCNAARCAR GCNCARGAYCARACNACNAAYAARGARAARMGNTCNAAYCCN------------------ ------AARGCNACNCCNAARGARGAYYTNCCNTTYATHACNCCNTCNGGNAARACNGAR TCNAGYYTNGCNTTYAAYGARGTNCARCARGCNATGTCNGARGCNCARGGNYTNYTNGAY AAYCARGARTGGATHACNGAYGAYTTYYTNAGYAARATHGARAARAAYGARAAYYTNYTN AARMGNTTYAGYGAYCCNCARTTYATGTCNGCNYTNCARGARTTYCARACNAAYCCNCAR GCNGCNATGGARAARTAYAARGGNAAYACNGARGTNGARAARTTYYTNATGGARTTYTGY GGNYTNYTNGGNGAYCAYTTYACNAARYTNGGNAGYAGYAAYGAYCARTCN--------- ------------------------------------------CARCCNACNGARAAYAAR AGYTCNAARCCN---CARCCNGTNGCNAARCARAARGCNCARAAYGAR------------ ---------------------------------------------CARYTNCARTCNGCN ACNCCNAARATHGTNGARATHGGNAGYGGNGAYGAYYTNGGNGAYGARCCNYTNAARGCN TCNAARTCNGARCCNAGYAAYTCNAARGCNAAYCCNAARCCNGGNGCNTCNCAYATHCAR ATHCAYGAYCCNCARAARGGNGCNGAYATHCARGARYTNCCNMGNGARCCNGARACNCAR ACNGAYGAYGAYGCNGTNMGNGARGTNYTNAAYGAYCCNAARGTNATGGARACNYTNATG GAYCCNAARATHATGGCNYTNATHAARACNYTNMGNGARGAYCCNGARAAYGGNCARMGN ATHATHGAYAARGCNGAYAGYGAYYTNAARGARAARGTNMGNTTYYTNGTNGCNMGNGGN YTNYTNCARTTYCARYTNAAYCARAAYAARGCNMGNYTNACNAAYGTNCCNTCNYTNYTN YTNCARGAYCAYGARAAYGARACNYTNTTYCARACNYTNGGNMGNYTNTGYGTNACNYTN GCNACNGGNGTNGTNCARYTNTAYYTNGCNGAYCARAGYGAYMGNGCNMGNTGGAAYAAR MGNTGYTGYGGNGTNGCNTGYTTYGTNAARGAYAAYTCNAARMGNTCNTTYTTYATHAAR GTNTTYGAYATHAARAARCARCARYTNYTNTGGGARCARGARYTNTAYAAYCARTTYGTN TAYAARACNCCNMGNGARTAYTTYCAYACNTTYGARGCNCAYAAYTGYCARGCNGGNYTN AAYTTYGCNGAYGARGAYGARGCNATHAARTTYAARAARGCNGTNGARGGNAARYTNAAY GARMGNMGNCARAARAARATGGARMGNMGNCARAARTCNGTNTCNAGYAARCAYGGNGTN GAYCARGGNCCNGGNGCNAAYCCN------------CCNCARMGNATGGGNGGNACNAAY AAYGCNGCNCCNACNCAR------ACNGTNGAYGTNAAYMGNATGAAYAAY------AAY AAYCARAARAARGARAARGAYAARAARAARGARAARGAYAARAARAARAARYTNACNAAR GARGAYATHGGNTCNCCNTCNAAYTTYGTNCAYATHAGYCAYGTNGGNTGGGAYCCNGAY AARGGNTTYGAYATGAAYAAYYTNGARCCNGAYATGCARACNYTNTTYCARTCNGTNGGN ATHAARCCNGARGAYAARGTNGAYAARGAYACNGTNGAYTTYATHTAYGAYTTYGTNGAR AARMGNGGNGGNATGGARGCNTTYAGYAARGARYTNMGNAGYAAY---------ACNAGY MGNCCNCCNGCNCCNCCNGCNAGYATGGGNMGNMGNGCNCARCCNCCNCCNCCNCCNGCN MGNTCNCCNGGNGGNCCNCCNCCNCARMGNAGYGGNGGNGCNCCNCCNCCNCCNCCNCCN TCNMGNGGNCCNCCNCCNCCNAGYATGMGNGGNGCNGTNCCNCCNCCNCCNCCN------ ------------------------CCNTCNMGNGCNATGCCNGCNCCNCCNMGNGCNCCN GCNGCNCCNYTNCCNCCN---------CCNCCNMGNCCNCCNTCNTCNGTNCCNCCNCCN CCNCCNGCNATGATGGGNAGY---GGNGGNTCNGCNGGNATHGGNGTNCCNCCNGCNCCN CCNCCNCCNCCN---ATGGCNTCNYTNTTYGGNGARCAYMGNYTNYTNACNAARAARGTN TTYGAYGARATHTAYATHCCNGARAARGAYMGNGAYAAYTAYAAYACNGTNCARGCNAAY GARGCNYTNGARGGNAARGTNGTNTGYYTNTTYTTYTCNGCNTCNTGGTGYACNCCNTGY CARCAYTTYGTNCCNACNYTNAARGARGTNTAYTCNGARYTNGTNCAYMGNAAYAGYCCN YTNGARATHGTNTTYYTNAGYTTYGAYAARACNGARGAYGARATGATHAGYTAYTAYCAR GARAARCAYGGNGAYTGGYTNACNGTNAARTTYGGNGAYCCNYTNAARCARGARYTNGTN GARMGNTAYTCNATHAGYGTNATHCCNAARYTNATHGTNGTNCARCCNGAYGGNGARGTN ATHAGYAGYAARGGNMGNAARGAYGTNCARGAYMGNGGNGTNGTNTGYATGMGNGCNTGG CARGCNGGNTTYGAYAARTAYATGCAYCAYAARGARCARGAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNGGNGCNTCNTAYGTNAAYATHTTYTAYTCNYTNYTNCAYGAYGAR AARTAYCCNGAYCARGAYAARGARTTYTGYGTNAAYYTNACNGGNYTNTTYATHAAYTCN GGNATHYTNYTNGGNACNGGN------GTNTCNGGNATGMGNAARCCNTAYMGNGARAAR CARGAYGTNTTYGAYGTNAARCAYYTNGCNTCNAARGARCCNTTYGARCARTTYAGYGCN TGGTTYGARGARGCNAARTCNATGCCNGGNGTNTTYGARGCNAAYGCNATGGCNYTNGCN ACNGCNACNMGNGARGGNAARCCNTCNGTNMGNATGGTNYTNATGAARGGNYTNAGYAAR GAYGGNGTNGAYTTYTAYACNAAYTAYCAYAGYMGNAARGCNCARAAYYTNATGGARAAY CCNGCNGCNAGYYTNATGTTYTAYTGGGARTCNYTNAAYAARTCNGTNMGNATHGARGGN AARGTNGARAARYTNTCNCARGARCARTCNGARAARTAYTTYCAYTCNMGNCCNMGNTCN AGYCARATHGGNGCNTGYGTNAGYGARMGN---CARAGYTCNGCNATHTCNTCNMGNGAY GTNYTNGAYAARMGNAARGARAAYYTNGARTCNCARTAYAGYGAYGARAGYGTNGTNATH CCNAARCCNGAYTAYTGGGGNGGNTTYMGNYTNGTNCCNGAYAGYTAYGARTTYTGGCAR GGNCARTCNAAYMGNATHCAYGAYMGNATHACNTTYMGNAARCCNACNCCNGGNGARGCN GTNGAYCCNGCNGTNACNTTYCARGGNMGNGARGGNTGGGTNTTYGARMGNYTNCARCCN ------------------------------------------------------------ ---------------------------YTNGARAAYGTNYTNAARGCNGCNAGYGARCAR CARTGYATHATGTCNGAYGARGTNGTNTCNTTYTCNATHATHTCNGTNACNMGNGAYGTN CARCAYACNAGYAAYCCNTGYTTYAAYATHCAYCAYAARTGYMGNTTYAGYTCNTCNATH GAYAGYAAYGGNGCNGAYTTYMGNATHGGNCCNTGGAARAARAGYCARCCNGAYGCNTCN GARMGNGTNTAYYTNMGNGCNYTNATHMGNGARYTNGARTGGMGNGGNTTYACNGTNACN TTYTCNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CCNYTNCARATHTTYTCNMGNAGYTTYMGNAAYAARACNACNYTNGGNCAR TCNAAYCARACNTAYACNCCNGARTCNCARGGNAAYTCNTTYTCNYTNATHAARTCNACN GCNTTYGTNACNGGNGTNTGYAGYTGYAGYTTYGTNGGNGCNATGATHTGGAAYTAYGAR AAYGTNMGNAARGTNTAYAARGAYATGGCNGCN------------GAYAARACNYTNCCN TTYAARGTNAAR---AARGCNTTYGGNTTYMGNCARCAYYTNAAYGCNATHTGGGARAAY ATGGAYTCNTCNACNAARYTNACNTTYGGNATHATHGCNGCNAAYGTNYTNGTNTGGATH YTNTGGAARGTNCCNMGNYTNCARTCNGGNATGATHMGNTAYTTYTCNTCNGCNGCNGCN CAYCCNMGNYTNTCNATGGTNYTNAGYAGYTTYAGYCAYATHAGYATHYTNCAYYTNATH GTNAAYATGTAYGTNYTNYTNTCNTTYGCNCCNGTNATHACNMGNACNTTYGGNCCNGAR CARTTYTCNGCNTTYTAYATHAGYGCNGGNACNATGTCNGCNTTYACNAGYATHYTNTGY CARMGNTTYYTNAARMGNCCNATGGCNGTNTCNGTNGGNGCNTCNGGNGCNATHATGGGN YTNYTNGGNGTNACNGGNYTNYTNTAYCCNAAYGGNCARYTNCARATHGCNTTYGTNTCN GARATHTTYCCNCAYTCNTTYTCNGCNGARACNGGNATHAARGCNATHATHYTNTTYGAY YTNYTNGGNYTNTTYATGGGNTGGAARGTNYTNGAYCAYGCNGGNCAYYTNGGNGGNATG YTNTTYGGNYTNYTNTAYGCNAARTTYGGNAGYAARATGATHTGGGGNAARMGNGAYACN GTNGTNAARTCNTGGCAYAAYYTNMGNGGNAARCCNAARTCNTCNGARGARATHGARYTN GARAARATHGARGCNATGMGNMGNCARTTYGCNAARTCNMGNAARAAYCAYGARGTNYTN TAYAARAARGCNATHGCNCARGGNAARCCNGTNTCNYTNAARTCNAGYCARCCNCCNACN ATHCCNMGNGGNTTYCAYTTYCAYTCNGAYCARMGNATHAARGGNACNGCNGARATGGCN GAYGAYACNTCNGCNAARGAYTTYGCNAARATGYTNMGNTCNTCNGGNCCNTCNAAYAAR TCNCARACNTCNTGYATGACNMGNCCNCARCCNTTYAAYYTNACNAARAGYACNTCNAGY YTNCARTCNGGNAARTAYATGTCNGCNGCNGARCARGTNATGGCNTAYAAYAGYGGNGGN GGNGGNGGNGGNGCNTCNTCNGTNACNTCNTCNGGNMGNMGNGCNGARTCNCCNACNYTN ACNATHGCNAARACNCCNAAYYTNACNACNMGNGGNMGNTCNMGNTCNYTNAARYTNYTN ACNMGNGAYGARGARGARGARGTNGARTAYGARAARCAYMGNCARCARCARTTYAARGCN CAYGGNGTNAAYCAYAARATHTTYAARGARCCNCARYTNGGNGTNMGNAARGTNCCNGCN AARCCNCCNACNACNGTNCARGARTTYAAYYTNCAYAGYAGYAGY------TCNCAYGTN MGNAARTCNTCNAARGAYTCNACNGGNGARAARACNGGNTTYCAYGCNAAYCCNATHAAY CAYAARATHYTNGAYGGNCCNACNGGNGTNAARCCNGCNGAYAARMGNCCNYTNACNGTN GCNCARTCNCCNGCNTTYTCNYTNAARAAYMGNYTNMGNCCNCCNGARGTNGTNCCNCCN ACNGARCCNCCNAARGTNTTYTCNAAR------CCNGTNCCNCAYATGGGNGTNCCNTTY MGNCCNCARYTNGARCAYAARTAYACNGTNACNAARCCNTTYGCNGTNGARCARCAYAGY AARGARATGYTNMGNAARAARGARYTNAARATHCARCARGTNYTNGARGARGARAARAAR GCNMGNGARTTYCAYGCNAGYYTNYTNCCNAGYGAYAGYCCNGAYCARYTNCCNGCNAAR MGNACNMGNCCNGTNACNGCNGTNGARCCNTTYAGYYTNGCNATHGAYGARMGNGGNAAR AARTAYCARGARGGNTGGAARTCNAARCARATHGARGARGARGARGAYCARGCNMGNTCN AARGCNATGTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GTNGARCAYGGNGGNAARGAYGAYCCNCAYGGNGGNGTNCCNATGGGN ATHCCNAAYCAYTTYTGYGAYGAYGGNAARAAYTTYACNTCNATHGAYTGGGAYCCNTCN TCNACNGAYGARTAYACNTGYYTNGARGAY------MGNGAYYTNGAYGAYYTNMGNCAY ---------AGYTAYGARTCNTGYGARGARATGGCNAARMGNCCNGTNCAYGTNTGYTTY CCNGARCARATHTCNTAYGAYGARGAYYTNCCNACNAGYGGNMGNCAYMGNCCNYTNTGG CCNCARTAYGGNGARTAYMGNTAYYTNCCNCCNCARMGNTGGYTNCAYTCNYTNGARCAY GGNGCNATHGTNTTYYTNTAYAAYCCNTGYGCNAAYGARGAYCARATHMGNAARYTNAAR GCNYTNGCNMGNGGNTGYATGMGNMGNCAYGTNATHTCNCCNTCNAARMGNATHCCNAAR CCNAGYATGTTYGCNGTNATGGCNTGGMGNTGYAARYTNGTNATGACNCAYGTNGAYGTN CCNAARACNGTNGCNTTYGTNMGNGARCAYGCNYTNCAYTCNCCNGARMGNTCNGTNTTY GCNGAYGGNCARTAYAGYGTNGCNYTNACNCAYCAYGCNAARATGGTNACNACNAARGAY GARATHAARYTNTGYCCNGARATGTCNYTNATGGARTAYGARCCNTTYGAYTCNAAYAAR AARAGYMGNATHGAYGAYGARYTNYTNCCNGAYYTNGAYGAYGCNGTNYTNMGNACNGCN MGNATGMGNAARAAYCARATHTCNAARTGYAARAGYGARGCNMGNAAYATHGTNGCNAAY TCNGTNAARTAYTAYAGYMGNGTNACNGTNAAYTGYGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AAYGAYYTNTGGGTNYTNGAYACNYTNACNYTNAARTGGTTYCARCCNATG CARATGAAYYTNGGNGTNCCNACNCARMGNGCNGCNCAYGGNATGTGYGCNATHGGNMGN AAYATHATHATHTTYGGNGGNMGNGAYATHGARGAYMGNCARAAYGAYYTNCAYATHTTY AAYATHGAYACNMGNAARTGGGAYACNGAYYTNAARYTNAGYGGNCARCCNCCNYTNCCN MGNTCNTTYCAYAGYGTNACNGCNGTNAARGAYAARGTNGTNGTNTTYGGNGGNMGNGGN MGNGAYAAYAGYCAYTTYAGYGAYTTYGAYATHYTNGAYYTNGARAARAARGARTGGTCN MGNGCNTCNGTNGARGGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGGATHGAYATGAAYGAR CCNGCNTCNTTYATHCCNCCNGAYMGNATGAAYTGYTCNCARAGYAAYTAYCCNAARTAY TGYCCNAAYATHYTNGGNGCNGGNGARAARGTNATGTAYGAYAARACNATHTGYATGGAY TCNCARCARAARGTNGGNYTNCAYTAYGAYGCNCAYAGYYTNTAYGGNCAYTCNATGGCN ATHMGNACNTAYAARGCNYTNGAYACNYTNAARGAYAARMGNCCNTGGACNATGACNMGN TCNTCNTTYGTNGGNACNGGNCARTTYGCNACNAARTGGACNGGNGAYAAYMGNGCNACN TGGGAYGAYYTNAARCAYTCNATHGTNTCNATHATHGARTTYGGNTTYTTYGGNTTYGCN ATGAAYGGNGCNGAYATHTGYGGNTTYTGGAARGARCCNTCNCAYGARYTNTGYATHMGN TGGCAYCARYTNGGNGCNTTYTAYCCNTTYGCNMGNAAYCAYAAYGGNMGNGGNAAYGCN CCNCARGAYCCNGCNTCNTTYGGNCARGARTTYGTNGAYATGGTNMGNCCNGCNYTNYTN ACNMGNTAYMGNYTNYTNCCNTAYATHTAYACNTCNATGTAYTCNGCNCAYMGNGARGGN MGNYTNGTNATGCARCCNYTNTTYTAYCARTTYCCNCAYGAYAARAARACNYTNACNATH GAYMGNCARTTYATGYTNGGNGAYAGYYTNYTNGTNTCNCCNGTNYTNGAYCARGGNGCN ACNAAYGTNCARGCNTAYTTYCCNGARGGNMGNTGGTTYGAYTAYTTYACNGGNGARGAR ATHAGYAARGGNGGNAARMGNGTNGAYYTNGCNACNCCNYTNGAYAARTTYAAYYTNCAY ATHMGNGGNGGNCAYGTNATHCCNTGGCARGARCCNGGNGTNAAYACNGTNGARAGYMGN GARAARGCNMGNGGNGTNATHGTNTCNYTNGAYGARACNGGNAARGCNCARGGNCARYTN TTYTGGGAYGAYGGNATHTCNAARYTNACNACNGAYAGYTAYAAYATHATHACNTTYAGY ATGGARAARGGNACNYTNACNATHACNGCNCARACNAAYAARTTYGTNACNAARYTNAAR ATHCARACNGTNGARATHTAYGGNYTNCCNMGNATGCCNTCNAGYGTNAARGTNAAYATG CAYYTNCCNGCNGAYYTNAAYGGNTTYACNCCNTTYCARGARTTYACNATGTCNGARYTN GGNGTNGCNCCNGGNGAYMGNCCNYTNACNTGYGTNYTNAGYGAYCAYCCNGGNGARYTN GTNAARACNGGNAGYCCNAAYTTYYTNTGYTCNGTNYTNCCNTCNCAYTGGMGNTCNAAY AARACNYTNCCNGTNCCNTTYAARGTNGTNTCNYTNGGNGAYATHMGNGAYGGNACNAAR GTNATHATHACNGCNGGNAAYGAYGARAAYTTYTGYTCNGARYTNMGNAAYAAYACNGCN ACNGTNAARAAYCARGTNGCNAARTTYAAYGAYYTNMGNTTYGTNGGNMGNAGYGGNMGN GGNAARAGYTTYACNYTNACNATHACNGTNTTYACNAAYCCNCCNCARGTNGCNYTNTAY CARAARGCNATHAAR--------------------------------------------- ------------------------------------------------------------ ---------ATGYTNACNATHACNGAYTTYATHAAYATHYTNAARCARTAYTAYAARACN TCNGGNACNAARATHGARGARYTNGARGARCAYAARATHGCNACNTGGMGNGARGTNYTN AARGGNMGNCARMGNCCNTTYGTNTCNATHTAYCCNGAYAARAGYYTNTTYGARGCNGTN AARACNYTNGTNGAYCAYCARGTNCAYMGNYTNCCNGTNGTNGAYGARATHACNGGNAAY GCNYTNTAYATHYTNACNCAYAARMGNATHYTNMGNTTYATGCAYYTNTTYTTYAARGAY YTNCCNCAYCCNGCNTAYATGAARAARTCNATHAARGARYTNGGNATHGGNACNTAYGAR AAYGTNATHACNGCNAGYCCNGAYATGACNYTNATHAARGTNYTNAAYYTNTTYTCNAAY AAYMGNATHTCNGCNYTNCCNGTNGTNGAYGAYAAYTCNGGNAARATHGTNGGNATHTAY GCNAARTTYGAYGTNATHAAYYTNGCNGCNGARAARACNTAYAAYAAYYTNGARATHACN YTNAARGAYGCNYTNGAYMGNMGNTTYGAR---AAYCAYCARGCNGGNGARAARGTNGTN TCNTGYCARTCNTCNGAYTCNYTNGARGAYGTNGTNAAYAARATHGTNAARGCNGARGTN CAYMGNYTNGTNGTNGTNGAYGARTGYGGNAAYGTNGAYGGNATHATHTCNYTNTCNGAY GTNYTNAAYTAYACNGTNYTNMGNCCNATHGARGARGTNTCNGARGARGAYTTYGTNGTN YTNGGNACNCCNGTNCCNGARYTNGAYGARACNACN------AARAARCCNACNACNYTN CARGAYYTNACNGCNAARGAYAARGARGGNMGNMGNMGNTTYCAYGGNGCNTTYACNGGN GGNTAYTCNGCNGGNTAYTTYAAYACNGTNGGNTCNAARGARGGNTTYACNCCNTCNGTN TTYGTNTCNTCNMGNAGYCARAARCARGARGAYGCNCARACNTCNMGNCCNGARGAYTTY ATGGAYGAYGARGAYYTNGARGARCAYGGNATHGCNCCNMGNAARTTYGCNACNGCNGGN AAYTAYTCNTCNGARGARMGNAARMGNAARYTNGARAAYGTNGCNGCNCARYTNGCNCAR TCNTCNACNYTNGAYYTNGGNGGNGCNYTNTCNGAYYTNATHATHCCNGAYTAYYTNCCN ATHGGNATHAARYTNYTNMGNAARATGGGNTGGMGNGARGGNCARGGNYTNGGNCCNMGN GTNAARAARAARAARAARAARACNMGNAARAARGARTCNAARAARGGNAARAARGTNTAY GGNTGYGCNMGNCCNCCNTCNGAYTCNGAYAGYGAYGAYTCNGAYTCNTTYATHCCNTCN AAYYTNAGYGAYYTNACNTTYGCNCCNTCNGAYGTNACNCCNGTNTGYYTNAGYGCNAAR GAYGAYGTNAARGGNYTNGGNTAYMGNGGNYTNGAYCCNTCNYTNGCNYTNCCNGGNTCN CAYGTNAAYYTNYTNGCNAAYCCNGTNAARGGNAARMGNGCNGGNAARGGNATHMGNGGN CAYGCNTTYGGNGTNGGNGCNYTNGARGAYGARGAYGAYGAYATHTAYGGNCARGAYAGY YTNTCNAAYTAYGAYYTNACNATGMGNGGNGAYGAYAARGGNCAYGAYGGNAAYTTYGGN TGGACNGCNCCNCARGCNCAYGGNAARCARAARGTNCCNGTNTCNTAYGTNGGNAARYTN YTNGARGGNTTYTGYYTNTCNTCNAARCCNYTNMGNCCNMGNAARAAYTTYCCNCCNCCN AARYTNCCNCCNAAYTTYAARCCNCAYCAYTGGTCNMGNMGNMGNAAR------AARGAR GARGAYGAYGCNAGYGGNMGNCARAAYAAYYTNAGYGTNGTNGAYMGNGGNYTNATGYTN GGNGARACNCCNATHATGAGYTCNGTNTTYGAYYTNGTNGGNTCNAARGAYAARTCNMGN ATGGARTGYGCNAARGARGCNGTNCARATGACNAARTCNYTNGAYATGACNYTNGGN--- ---------ACNGCNGCNATHGCNAGYGTNGTNAAYAARAARGGNGARAARGAYTCNCAR TCNCCNAGYGTNCCNGGNCCNGARCARAARAAYCCNCCNTCNTCNAARTTYYTNTCNMGN TTYACNGARGCNAGYACNACNAGYAAYGGNAAYAARGAYGGNGAYTCNGTNGAYAARAAY ACNAGYACNTCNYTNTTYAARGGNTCNYTNAGYYTNCARCCNTTYMGNAARGAYCCNGCN AARCARGCNMGNTTYGAYCARTAYYTNGCNTGYGTNCARCARAARYTNCCNGAYCCNTAY AGYCARGTNTCNAGYAGYMGNATGACNGARTGGGARAARGCNMGNGARMGNGAYGARTTY AAYMGNTCNGCNMGNYTNTAYMGNCCNATGTCNGCNATGATGTCNGCNMGNTTYGTNGTN GGNGCNATGYTNGAYGAYAARAAYCARGAYTCNAARACNGARGCNGGNGGNGARGTNACN GAYGARGTNAARGCNTCNGARATGMGNATGTTYGGNAARYTNACNMGNGARGAYTTYGAR TGGCAYCCNGAYAARYTNGTNTGYAARMGNTTYAAYGTNCCNAAYCCNTAYCCNGGNTCN GAYATHGTNGGNYTNCCNACNGTNAARMGNGAYAARTTYTCNATHTTYAAYTTYYTNAGY TAYGGNGAYTAYMGNCCNAARGAR------------CCNGAYACNGGNTCNGARMGNTCN GCNGARAARGARGTNCCNGGNAARTCNGARMGNGGNACNCAYAARCCNGARAARAARAAR GCNACNYTNTCNTCNATHTTYAARGTNYTNGAYGAYCCNGAYTTYCAYAARCCN------ ------CCNACNGAYGTNAARTCNGARGARCCNYTNGARCARAARATHGARGGNAARGAY GCNGGNCARGARGARGARAARCARGARGARGARGARGARGCNGAYGTNGAYYTNTTYMGN GCNATHTTYAARAAYTCNGAYTCNGARGAYTCNGARGAYGAYMGNAGYGAYGAYGAYAAR GAYGARGAYGAYAAYGAYGAYAARMGNGAYGAYGAYGAYAARGARGAYAAYCAYTCNGTN ATHYTNGAYAARCAYTCNAGYGAYATHGCNGAYYTNAGYGTNMGNGGNMGNCCNGARATG GARGGNGARGARGARAARYTNACNTCNATGGARGARACNTCN---------------TCN CCNGCNGARACNGGNTCNGGNCCNAAYAAYCARYTNGCNATHCCNGCNCCNGCN------ ------------------------MGNTCNGGNACNMGNTGGGAYTCNAARTCNGTNTTY AGYGTNYTNGAYGARYTNAAYGARGARATGCAR------------------------TCN GCNCARAARCCNATGGARATHGARAAYGAYATHTCNGAYTCNGARTAYGGNCCNGCNYTN CCNCCNCCNCCNCCNTCNAARCCNACNTCNGARGCNTCNATHTCNAAYMGNACNYTNGTN MGNGARAARGAYGARAAR---------AGYAARGARAARGARMGNCARAARCAYAARCCN AARAARGAYAARAARAARAARTCNAARCAYAARAARGARAARAARCAYAARAARAGYAAR AARTCNTCNTCNAARTCNMGNMGNAGYAARCCNGARAGYTCNGGNAGYGARGCNGAYTCN GARACNAGYGAYGAYTCNGAYGTNTCNGAYAARGARYTNYTNAAYMGNTTYYTNCARGTN TTYAARATGAARTCNGGNTCNYTNACNGTNTGYGTNCCNTCNGARATHGCNCARGTNGTN MGNMGNGTNYTNGARGARAAYAARYTNTGGGAYTGYAGYMGNAARYTNCARMGNCAYGGN GARACNGTNGCNATHCCNATHYTNAAYTAYAAYGGNCCNCARATGTCNACNYTNYTNCAR GAYTAYCCNGGNGCNGTNATHAARGARYTNTCNYTNCCNGCNTCNGCNAARAGYGTNMGN YTNATHACNAAYAARYTNGCNYTNYTNTCNGARGTNCCNMGNAARTGGGARMGNCAYGGN GAYYTNATHYTNYTNCCNTCNTCNGCNTTYACNTCNTCNGCNTGGGGNMGNYTNGGNGAR GARYTNTGGCARACNGTNGCNTCNGTNYTNTCNTGYCAYMGNYTNGCNMGNCAYTCNACN GTNGCNAAYAAYGGNTTYMGNACNCCNCARGTNTCNYTNYTNYTNGGNAARGAYGGNAAR GTNGTNCAYATHGAYAAYGGNATHAARTAYAGYTTYGAYGTNACNAARTGYATGTTYAGY TCNGGNAAYATHAGYGARAARYTNMGNGTNGCNTCNTGGGAYTGYTCNAAYGARACNGTN GTNGAYYTNTAYGCNGGNATHGGNTAYTTYACNYTNCCNTAYYTNGTNCAYGCNMGNGCN MGNCAYGTNCAYGCNTGYGARTGGAAYCCNGAYGCNGTNGARGCNYTNMGNGARTCNYTN TCNTTYAAYGGNGTNGCNGAYMGNTGYACNATHCAYCARGGNGAYAAYMGNCARYTNCAR YTNTCNTGYGTNGCNGAYMGNGTNAAYYTNGGNYTNATHCCNAGYAGYGARGAYGGNTGG MGNGTNGCNACNMGNYTNYTNAARTCNACNGGNGGNGTNYTNCAYATHCAYCARAAYGTN ACNGTNTCNCCNTAYGTNGGNCAYCAYTAYGCNGGNCCNGGNAAYCAYTTYTGGAARTAY GAYGAYTTYAARYTNCCNAARTTYGGNATHGGNTTYACNAAYATHTGYCCNMGNACNACN MGNGGNAGYTCNGAYYTNMGNAARAGYGARATHAARGARGGNGGNGARGTNYTNAARMGN AARATHYTNAARTAYMGNCCNMGNATHGCNGTNTTYAAYGGNAARGGNATHTAYGARGTN TTYAGYGCNAARAARGARTTYAGYATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AARGAYYTNCCNAARATGGAR GARGARGTNACNGARTTYATHAAYCAYTGGGARAARGCNAAYCARAARGARTTYYTNATH AAYGGNYTNMGNTTYCCNCARTAYGTNATHMGNCARTGGGARGAYTTYCAYMGNCAYAAR GARCARGARAARCARGAYMGNGTNAARGCNMGNGCNAARCARACNCARGARGARATHATG TAYGGNAGYAARTCNGCNYTNCAYACNCCNGGNAARMGNAARATHGGNGCNTCNACNACN CCNATGMGNACNCCNYTNAARGCNMGNAARYTNAAYGGNACNGTNAARACNCCNACNTCN ACNGGNMGNYTNCCNCCNATHAGYMGNATHCARCARAGYTCNGTNTTY---------CCN YTNTGYACNCCNAARACNCCNATG---GCNTCNAAYAARAARMGNMGNTCNATHMGNYTN ATGCARAARGAYGCNACNGARMGNMGNAGYTCNAAYTCNAARMGNMGNMGNTCNMGNGAY ATHTTYTCNCAYACNACNGTNAGYAGYGAYAAYAAYACNACNTCNTCNYTNGCNTCNACN TGYTCNTAYAAYGARTTYGCNAAYGGNYTNTCNAARCCNAAYTGYMGNAGYAGYGTNGCN CCNTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGTNGGNTTYATHGTNCCNAAYTCN AGYYTNAAYTCNTTYGGNTCNATHTGYTAYTGYATHATHACNGTNGGNATHCAYGCNTAY GCNTGYTAYAARGAYATHATHMGNTAYCARGARGCNGAYGAYMGNGCNTGGCCNAGYAAY MGNGGNGARCCNCCNACNGARGTNACNTCNYTNYTNGGNTTYACNATHYTNTCNYTNYTN GTNATGCCNTTYTTYTGYGTNGCNTCNGTNATHAARGTNGGNAAYTTYGCNAGYGAYGGN GCNAARYTNGGNMGNGAYCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CCNTGYGCNACNYTNGCNAARAAYYTNYTNGGNCARTAYATHGTNMGNTCN GTNGGNTCNCARATHATHAARGGNCARATHGTNGARACNGARGCNTAYATHGGNCCNGAR GAYAARGCNGCNCAYAGYTAYCARGGNAARMGNACNCCNMGNAAYGARGCNATGTTYATG ACNCCNGGNACNAGYTAYGTNTAYAAYATHTAYGGNATGTAYTGYTGYYTNAAYATHTCN AGYMGNGGNGARGGNTCNGCNGTNYTNYTNMGNGCNYTNGARCCNGTNGARGGNCARGAY GTNATG---------GCNGARGGNMGNYTNNNNAAR------ACNAARAARCCNTTYAAR GARAARGCNYTNACNAAYGGNCCNTCNAARYTNTGYCARGCNYTNCAYATHAAYAARAAY GAYTTYAAYAARGTNGAYYTNACNYTNTCNGAYGCNYTNTGGYTNGARAARGGNGTNGAY GTNGGNAGYGGNAAYATHGTNAGYTGYGCNMGNATHAAYATHGGNTAYGCNGARGAYTGG ACNGARAARCCNYTNMGNTTYTAYATHCARGGNAAYCCNTGYGTNAGYGTNMGNGAYAAR AARGCNGARACNAARGGNAAYTCNAARGGNAARATGGTNTGYTAYTAYACNAAYTGGGCN CARTAYMGNCCNGGNYTNGGNAARTAYACNCCNACNGAYGTNGAYGCNTCNYTNTGYTCN CAYATHCAYTAYGCNTTYGCN---AARYTNGAYTCNGGNMGNATHGCNCCNTAYGARTGG AAYGAYGARAGYACNCARTGGATGGTNGGNATGTAYGARAARYTNAAYGAYYTNAARAAR ACNCAYCCNGGNYTNAARACNATGYTNTCNYTNGGNGGNTGGAAYYTNGCNTCNGGNCCN TTYACNMGNATGGTNGCNTCNCCNCARAGYMGNGCNGTNTTYATHAARAGYGTNYTNGCN TTYYTNMGNAARTGGTCNTTYGAYGGNYTNGGNYTNGAYTGGGARTAYCCNGGNTCNMGN GGNAGYCCNGCNGGNGAYAARCARMGNTTYACNYTNYTNGTNCARGARACNATGGCNGCN TTYCARCARGARTCNGCNTCNACNGGNMGNCCNMGNYTNYTNYTNTCNGCNGCNGTNTCN GCNGGNAARAGYACNATHGAYTCNGCNTAYGARGTNGAYAARGTNACNAGYGTNYTNGAY TAYGTNGTNGTNATGACNTAYGAYTTYTTYGGNGCNTGGAAYCCNTAYACNGGNYTNGTN AGYCCNYTNTAYGGNCCNAARAAYGCNACN---GGNATHGAYGCNATHTTYAAYGTNGAY TTYGCNGTNMGNTAYTGGGTNTCNAARGGNTGYCCNAARGAYAARATGGTNGTNGGNGTN ATHTCNTAYGGNMGNTCNTTYACNYTNACNGAYCCNTCNAAYTCNGGNYTNMGNGCNCCN GCNAAYGGNGCNGGNTCNCCNGGNCARTAYACNMGNCARGCNGGNTTYYTNTCNTAYTAY GARGTNTGYMGNATGATHAGYAARGGNGCNAARATHGTNMGNYTNGCNGAYGARAARGTN CCNTAYYTNGTNYTNGGNAAYCARTGG--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------MGNCCNGTNYTNAAYCARTCNGARCCNATHAARGTNTAYGTNACNGTNAAY TTYGTNAAYYTNATHGAYATHGAYGARGTNAAYCARMGNATHACNAAYAAYYTNTGGGTN AAYTTYTCNTGGTGGGAYGARYTNMGNACNTGGAAYCCNGAYGAYTAYGGNGGNAAYGAY GTNATHCAYCCNAARACNACNGAYATHTGGMGNCCNAARACNATHATHACNAAYTCNGCN GGNGARMGNGAYATHTTYCARGAYATHGAYAGYCCNYTNTCNATHTAYTCNTCNGGNGCN ACNMGNTGGTAYGCNGGNGGNATHTTYTAYTCNGTNTGYYTNATGGAYYTNACNTAYTTY CCNTTYGAYACNCARGARTGYACNYTNAAYGTNATGTCNACNAAYYTNGGNTCNGARATH GARTTYATHCCNGTNTTYCCNACNTTYYTNGCNGTNGAYTAYATHGCNAAYGGNGARTGG TCNYTNAARAARTCNGARGTNCCNAARCCNTAYCCNGTNGGNCCNGGNGARACNYTNACN TTYYTNTAYYTNTCNGTNACNTTYGARMGNMGNCCNATHTTYTAYYTNATHAAYATHYTN ATHCCNACNATGTGYYTNTCNTTYYTNTCNYTNTTYGGNTTYGTNGTNCCNAARGAYAGY GGNGARMGNGCNTCNTTYGCNATHACNGTNYTNYTNTCNYTNGCNGTNTAYATGGGNTCN GTNTCNGGNCARYTNCCNGCNAAYTCNGAYACNTTYCCNYTNATHAGYGTNTAYATHTTY AGYYTNYTNTGYYTNAGYATGYTNTCNGTNYTNATHATHGTNYTNCARATGMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHMGN CARGGNATHTAYCARGGNGCNGCNYTNMGNTTYACNYTNACNATHCCNCAYAAYTAYCCN GAYGGNAAYTGYCCNATHYTNGTNTTYGARCAYCCNGTNTTYCAYCCNYTNGTNGAYCCN GAYACNGGNGARYTNGAYGTNAARMGNGCNTTYCCNMGNTGGMGNMGNAAYGTNAAYCAY YTNTGGCARGTNYTNYTNTTYGCNAARAARGTNTTYTAYAAYATHGAYACNAARATGCCN TCNAAYCCNGARGCNGCNGTNYTNTAYGARCARGARCCNGARYTNTTYAARAGYAARGTN TCNGARTCNYTNGARGCNGCNMGNGARMGNYTNTAYCARCCNCCNTCNYTNGAYGAYCCN YTNGCNYTNMGNTTYAGYCCNTGGAAYGARGCNGTNCAYCCNGAYTCNMGNMGNCARATG GTNCARACNTCNAARAAR---TGYGARGGNGAYAAYTCNGCNAAYCCNTCNGAYYTNGGN YTNACNTGGATGGARTCN------ACNCAYATHTTYGCNACNGAYGGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AAYMGN------GAYTCNTAYTTYGGNTAYYTN------------AARAAR CCNTCNGTNCAYAARTAYGARGARCARTAYTCNGCNGGNATGGTNTCNGCNATGGAYGAR GGNGTNGGNAAYYTNACNCARGCNYTNAARGAYGARGGNYTNTGGGAYAAYACNGTNTTY GTNTTYTCNACNGAYAAYGGNGGNCARGTNCAYGARGGNGGNAAYAAYTTYCCNYTNMGN GGNTGGAARGGNTCNYTNTGGGARGGNGGNTTYCAYGGNATHGGNTTYGTNTCNGGNCCN YTNGTNAARTCNCCNGGNACNGTNACNAARGARYTNATHCAYGTNACNGAYTGGTAYCCN ACNYTNGTNAARYTNGCNGGNGGNAGYYTNAAYGGNACNAARCCNYTNGAYGGNTAYGAY CARTGGGAYACNATHAGYACNGGNGCNCCNGGNAARMGNCAYGTNYTNYTNCAYAAYATH GAYATHYTNTAYCARAARAAYGGNCARCARATGTAYAAYCAYACNTTYGAYACNMGNATH MGNGCNGCNATHMGNGTNGGNGAYYTNAARYTNATHACNGGNGAYCCNGGNAAYGGNTCN TGGGTNCCNCCNCCNAAYCAYGARCCNGARGTNCARGARTCNAGYMGNAARAAYGTNTGG YTNTTYAAYATHACNGCNGAYCCNACNGARCAYCAYGAYYTNTCNGAYAARATGCCNGAY GTNGTNGTNTAYATGYTNAARCARYTNGARTAYTTYAAYAGYACNGCNGTNCCNCCNMGN TAYCCNMGNTAYGAYMGNAARAGYAAYCCNGCNYTNCAYGGNGGNGTNTGGGGNCCNTGG GGNATGTGYCARCARTGGAARGGNTGYAGYAARMGNGAYAARAGYGGNGTNMGNGARACN AGYATHGTNACNTCNACNMGNAAYGAYACNCAYYTNATGYTNYTNGTNGGNTCNAGYAAR CARTGGYTNTCNYTNTTYYTNAAYAAYGAYTCNGARGAYGAYGTNACNGARACNGAYATH GARACNCCNYTNYTNGAYATHACNCCNAARGGNGAYATHGTNTAYGAYYTNGGNCAYAAY GCNACNATGGAYATHGTNTTYCCNCCNGARAAYGAYMGNGAYGGNCCNGGNAGYGGNGCN TCNTAYYTNTTYGTNAARCCNMGNGAY---ATHAARGTNATHATHGGNTTYGAYMGNGAR GAYGARYTNTAYTAYCCNGGNGARCARGCNAARYTNATGGAYAARGTNGAR---ATGACN GTNTGYATHAAYACNTCNATHATHCCNTAYTCNGGNYTNYTNAARYTNTAYTCNGGNGTN ACNMGNAARAARGGNYTNGTNCARMGNGTNGARAAYCAYAARGARATHGTNYTNMGNCCN TCNACNCARAARGGNCCNTTYCCNMGNGCNTTYYTN---------------MGNCAYAAY GARAARGARAAYGARAAYGGNGARGTNAGYYTNTGYAGYTAYGGNMGNGTNTGYCARMGN TAYTGYCARTTYTTYGGNAARTAYYTNTCNAGYYTNGARYTNTTYAARACNGTNAAYGGN CAYATHGARATHGCNGAYGARACNMGNGTNTCNTAYMGNAARGCNGGNACNTTYGARYTN AARCCNGTNGARGGNGAYTCNTTYCCNGTNACN---------TAYACNTGYMGNGCNGGN AAYGCNGARGGNCARACNGCNGTNTAYAAYCAYGTNGTNGTNTTYGGNTAYGAYGTNAAR GTNYTNACNAAYGARTCNAGYGTNGARATHTTYGAYAAYGGNACNGGNAARATHGTNTGY ACNGCNMGNGGNATHCCNYTNCCNAARGTNGARCCNGARACNMGNGTNCARGARGGNCAR CCNACNCARYTNCAYTTYTTYYTNCCNCARYTNGCNGAYACNATGAGYGARGTNTCNGGN ACNGCNACNGCNMGNAGYTAYTAYCARGARCARMGNYTNGARYTNYTNTCNMGNAAYGAR GAYTCNCAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNAARYTNAARAARGAYAARATGTCNAAYTCNCCNMGNAAYMGNMGNYTNGCNAAR YTNMGNACNAAYAAYTTYMGNAARYTNMGNAAYGGNGGNGAYCAYCAYACNACNACNGCN GCNGCNACNGTNACNCCNGCNTCNGCNGCNGTNACNACNGCNGGNGTNACNGTNTCNTCN TCNGCNGARYTNGGNGGNGCNGAYTAYCAYGAYGTNCARGAYCAYATHCCNAAYTAYGAR ACNATGAGYYTNGARGARMGNAARGCNYTNYTNYTNACNAARTGYGGNGTNATHTCNGAR ATHACNAARAARATGTGYACNMGNTCNACNAARTGYGCNCARCAYACNGAYGARCARMGN MGNCAYGTNMGNCARCAYYTNYTNMGNCARAGYMGNACNCAYGAYYTNGARGAYATHCAY ATHGAYATHGAYACNTAYGAYGAYGCNGARTCNCARTCNYTNMGNGARTCNYTNCARTGG GARGCNTCNTCNAAYTCNTCN---------------------AAYAAYAGYACNTCNAGY TCNYTNAARCARCARMGNACNACNGCNGTN------AARTCNTCNGGNGGNAGYAARTCN AGYAARAGYAARAARTCNAARGCNGTNAARGCNACNATGAGYGTNTCNAAYAAYAAYAGY AGYAGY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGNTAYCARACNATHTCNAARACNTAYMGNMGNYTNCAYCCNCAYYTN TGGGARTTYAARCCNTCNTTYGTNGAYAGYATGYTNTCNAAYATHGTNTCNYTNATH--- CARATHTCNAGYAARGARGARGCNGARAARGCNATHYTNCAYAAYGGNGGNAAYGTNYTN GGNYTNCAYYTNTAYMGNATHCCNGTNTTYTCNACNGAYTTYTGYAARCARYTNGTNGAR GARYTNTCNCAYTTYGARGAYAGYTCNTGYCCNAARGGNMGNCCNAAYACNATGTCNAAY TTYGGNATHTCNYTNGAYGARATGGGNYTNTCNGARGGNYTNYTNACNCCNYTNATHGCN GARTAYATHCARCCNYTNGTNACNGCNYTNTTYGGNCAYTGGTGYCARGARAARYTNGAY TCNTTYMGNTCNTTYTCNGTNYTNTAYGGNCCNGGNAARGAYACNGARYTNAGYAARCAY TAYGAYAAYGCNGARGCNACNYTNAAYGTNTGYYTNACNTCNGAYTTYGARGGNGGNCAY YTNGARTTYGTNGGNYTN------------------TGGGAYGGNCCNGAYTCNGARAGY TAYACNGTNATGCAYGARATHGGNAARGGNATHYTNCAYYTNGGNCARCAYACNCAYCAR GCNYTNCCNATHGTNTCNGGNACNMGNTGYAAYYTNATHYTNTGGATGMGNAGYTCNGCN GTNMGNAAYAARTTYTGYMGNATGTGYGGNTCNAARCCNGTNGTNYTNGARGTNCCNTTY GCNGGNGAYGGNTTYACNACNCCN------------------------------------ ------------------------------------------------TAYCCNAAYAAY ACNACNATGCCNACNATHTGYACNAAYAARTAYTCNMGNGAYCCNGTNGGNMGNATHTAY GGNAAYTTYATHTGYCCNGGNCARAARGARGTNCAYAAYGARMGNTAYTGYTGYGGNCAR MGNTTYMGNGARTAYTGYTGYAAYGTNACNGARGCNAARGARTAYTAYAGYMGNCAYCAY ATGGGNGGNGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TTYTCNATHCARACNACNTGGGAY GAYCARTGYYTNTGYCAYGAYCCNGTNAARATHTCNYTNAGYCARAGYCCNAAYGGNGAY YTNYTNATHAARGTNGAYGCNCCNTAYTTYAAYAGYCCNGCNAARCCNAAYGGNCCNGTN GGNCARCCNTTYCCNCARYTNTGGGAYTAYGARGTNGTNGARGCNTTYTTYYTNAAYGAY CARGAYCARTAYYTNGARGTNGARYTNAGYCCNCAYGGNCARCAYYTNYTNYTNYTNYTN AAYGGNMGNMGNAARATGGTNAARGAYAARYTNCCNYTNAGYTTYACNGCNACNATHAAR GGNGAYAAYTGGAGYGGNGARGCNGTNATHCCNMGNGAYTAYYTNCCNTCNTCNGTNACN AARTTYAAYGCNTAYGCNATHCAYGGNGARGGNGAYGARMGNGARTAYGARGCNYTNTAY CCNGTN---------ACNGARGARYTNGARGGNATGCARCCNGAYTTYCAYMGNYTNGAR YTNTTYCARCCNYTNGAYATGAGYGCNATHYTNAGYAAYTAYGAYGCNACNCAYGTNTCN CCNYTNTGG------------------AAYGCNCARGCNGARYTNCARCARYTNMGNAAR GARMGNGCNMGNYTNYTNGAYYTNCARAGYCARYTNAARCAYYTNCARAAYGTNGTNGGN MGNGGNGGNGGNGARCARGARGARMGNMGNGARGARATHTGYGGNAGYGARAARACNGAR ACNGARCARGCNCCNAAYGCNACNGTNGTNACNTTYGCNTCNAAYGAYGARYTNTAYAGY AARATGMGNMGNCARMGNATHYTNMGNGARGARYTNMGNTCNAARAARAARGARYTNGAR GCNATHATGAARAARGAYMGNAAYAARMGNCARTAYTCNMGNAAYCARGAYAAYCARAGY GAYACNGTNTCNYTNAAYACNGAYACNTTYGGNATHCCNGCNAGYGTNGAYGCNGARGAY GARGAYGGNAAYGCNGAYGARGAYGAYGAYGGNTAYCCNAGYGAYGGNATHGTNCARGTN GARGARGARGARGARGARAAYGAYACNGAYAAYGGNACNTAYACNATHGARGCNGAYGCN MGNCARMGNAARAAYATGMGNAARCCNGGNCAYATGGGNATHGGNGCNMGNCCNAARACN TCNMGNGGNMGNCARACNTTYCCNCARCCNGCNTAYACNGAYCARACNACN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GCNCAYCARCARGARYTNCAYGGNAAY AARMGNCARTTYYTNTGYMGNTGYTCNTTYYTNGARATHTAYCARGARCARATHTTYGAY YTNYTNGAYCCNACNTCNCARGGNYTNCAYYTNMGNGARAAYATGAAYAARGGNGTNTTY GTNGAYGGNYTNATHGARCARGTNACNTGYAGYCCNAGYGAYGCNTAYCARGTNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYGAYCCNMGNAARMGN AAYTTYACNGARCARGARYTNAARCCNCARCCNATHATHAARAARTCNAARAARATHTTY GTNCCNGAYGARYTNAARGAYGAYAARTAYTGGGCNMGNMGNCAYAARAAYAAYTAYGCN GCNAARMGNTCNMGNGAYGCNMGNMGNGTNAARGARAAYCARATHGCNYTNMGNGCNGCN TAYYTNGARAARGARAAYAARTGYYTNAARGAYGARATGGCNAARYTNMGNAARGARAAY GCNAARYTNAARACNATHGCNGAYAARTAYGARCCNGGNGCN------------------ ------------------------------------CAYMGNCAYACNATGTCNGTNATH CCNYTNAGYMGNCARCAYAGYTCNAAY---GCNYTNGARAAYGTNGAYACNMGNTTYATH TCNCAYAAYAARGCNATHCARMGNATGGGNATHCCNCARAGYMGNAGYAARMGNGCNCAR TCNGCNMGNGTNMGNGCNMGNTCNGCNAARAARGAYGARGTNAARGCNATGGAYATHTCN YTNAARGAYYTNGTNGGNGAYATGCCNTCNAGYGGNCAYTTYGTNGAYACNGARGCNYTN GGNGARCARMGNATHATHACNCCNTTYAAYAAYAGYMGNMGNMGNCCNCARACNTCNCAY ---CCNMGNTTYCCNCCNAAYACNTAYAAYGAYCCNGGNMGNTAYTCNAARGGNGAYGTN TTYGAYGTNMGNGARACNGAYGGNGTNAARAARCCNMGNCCNGTNAGYGCNTCNAGYYTN MGNGARGCNGAYGCNGCNMGNTCNMGNCCNMGNTCNGGNTCNTTYTCNAARMGNGAYAAR CARTCNCARGCNTTYATHACNCARAARAAYGARMGNTCNYTNMGNTAYGARGCNACNAAR CCNGTNTAYGTNTTYCCNAARCARTCNCCNACNAARCCNMGNMGNAAYTCNGAYGAYMGN GTNTCNCARYTNATHMGNTCNAAYAGYCAYCCNGGNYTNATGTCNCARACNGAYGTNATH AGYGCNTCNAGYGCNGCNAARATHCAYCCNACNAAYAAYTAYTAYAAYCARACN------ ATGGGNCARGAYAAY------------------MGNGGNGTNGARCAYTTYGCNGGNGAR GARTAYCCNGARAAYGARTTYGGNTTYGARAAYTCNGARATGGAYTCNATHCAYAGYAAR CCNCCNATHTCNATHMGNGTNAAR------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARAAYTAY YTNAAYTCNGTNAARCCNYTNGTNACNGAYGARGARTAYMGNCARACNGARTTYATHTGY CARCARTTYGCNTCNGGNGTNGGNAARGARYTNCARCARAARYTNYTNGARMGNGCNAAR GGNCARMGNAAYTGGYTNGARAARTGGTGGGARGAYGCNGCNTAYYTNGARYTNMGNTTY CCNYTNCCNYTNATGAAYATGGGNGGNCCNGGNCCNTAYACNGARGAYGTNTGGCCNGCN AARGARGGNACNCARAAYTTYMGNGCNGCNATGACNACNTAYCAYACNGTNAARATHTGG CARTTYATHCAYMGNGARCARTAYAARCCNATGAARGAYGGNAARGGNMGNCCNATGTGY ATGCAYCARTTYMGNMGNGTNTTYAAYGCNTGYMGNATHCCNGGNGTNTCNMGNGAYAAR YTNGTNGARTAYTTYAARACNGARTCNGARGGNGAYTGYCCNTCNCAYYTNGTNGTNATG TGYAARGGNCAYATGTTYYTNATGAAYACNYTNGAYGAYTGYGGNGARGTNYTNACNCCN YTNGARYTNGARGCNCARTAYAARYTNGTNMGNCARGARGCNGARAARYTNGGNGCNCCN CARGARGTNAAYTAYYTNACNACNYTNCCNMGNACNGCNTGGGCNGARTAYMGNAAYATG YTNYTNGCNAGYCAYCCNCAYAAYTAYGARGTNYTNGARAARATHCARAGYGCNATGAAY TTYTAYAGYYTNGARGAYGARAAYGCNGTNGAYYTNTCNGAYYTNGCNAAYAARTCNYTN YTNGGNAAYGCNCARAAYMGNTGGTGYGAYAARTCNYTNTCNATGGTNACNTAYAAYAAY GGNACNGTNYTNTGYACNGCNGAYCAYTCNTTYTGYGARGGNATHATGATGGTNTAYGTN TGYGGNTAYGTNCAYCARAARYTNAARGARTCNAAYGGNYTNTGGCARGGNACNAAYGTN GTNMGNCCNCARCCNCCNCCNGTNCAYYTNAARTTYGTNGTNCCNGAYGARYTNAARCAY GGNATHGARATHGCNAARAARGCNTAYAARGARYTNCARAGYTGYGCNCAYTGYGTNATH TAYAARTAYAARGGNTAYGGNAARACNTAYTGYAARCARATGAARYTNCAYCCNGAYGCN TAYTGYCARYTNGCNYTNCAYYTNACNTTYTAYACNYTNCAYGGNMGNATGGCNCCNGGN TAYGARACNGCNCCNATHAARCARTTYTAYCAYGGNMGNACNGARACNYTNMGNTCNTGY ACNATGGARGCNTAYGAYTGGTGYMGNAGYATGYTNGAYGARTCNTGYTCNAAYGCNAAR MGNTTYGARYTNYTNGCNAARGCNGCNGCNAARCAYAAYGCNAARATGGCNGARGCNTGY GARYTNAARGGNTGYGAYMGNCAYYTNATGGGNYTNTCNYTNATHGCNAARGARGARAAY ATGCCNYTNCCNATGYTNTTYCARGAYCCNTCNTTYGTNAARAGYGGNGGNGGNGGNCAY TAYYTNYTNTCNACNAGYACNGTNGGNTAYTCNACNATHATGGGNGGNGTNYTNCCNATG TGYGARAAYTGYTAYGGNTGYTTYTAYMGNGTNAAYGAYAAYGTNYTNACNTTYTTYATH TCNACNTGGAAYGCNGAYAARATGACNAGYAGYAARGGNTTYGCNGAYGCNYTNGGNMGN AGYYTNGAYMGNATGMGNGAYACNATHGAYCARGCNGTNAGYTCNGCNAARGCNMGNYTN CAYAAYCARYTNGARAARAAYMGNMGNAARCARATGMGNGARTGYTTYAAYTAYYTNCAR CARTGYATHCCNACNYTNYTNACNATHAARGAYGCNACNTGYGAYGAYTCNGGNGARTAY ATHTGYAARGTNACNTAYMGNATHAGYGGNCARAAYGAYGTNGARGARAGYGARTTYYTN AAYAGYACNGTNATHGCNTCNGARATHTCNATGACNATHYTNTCNTCNGGNTCNGARGCN GCNTAYAARGTNAAYGAYTCNATHACNGTNAARTGYAARGCNAARGGNCCNGAYGAYTTY CARTTYTTYTGGAARMGNMGNTGYCCNATGGARTTYACNTCNAAYCCNYTNTTYGTNMGN TAYCCNTAYCARAAYGAYATHAARGARGTNTAYGAYAAYMGNGGNCARMGNAGYMGNTGY GAYGTNAARAGYCAYAGYCARGARYTNACNTTY------GARATGGAYATGGARGAYTGY ATGATHMGNTGYGAYTTYGGNGARAGY------GAYMGNYTNTCNGAYAAYATHATGGCN AAYTTYACNTTYMGNATHGARGARGTNACNACNGAYACNCCNTCNGGNGGNMGNTCNTCN AGYAGYGGNTCNAGYGAYGAYYTNGTNATHGGNYTNGTNGTNTCNYTNYTNYTNGTNGCN ATHATHGTNGCNGCNGTNYTNYTNTAYGTNTGYTGGTGGMGNAARMGNACNCCNAGYGAR GAYAARTAYAARGAYGARCCNGAYGTNGGNMGNGAYTCNCAYGAY------CAYGCNCCN CCNCCNGTNTTYTAYTCNAARCCNAAYAARCCNCCNAARAAYGAYATHGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GGNATHGCNYTNAARTAYGGNGTNACN GTNCARGAYYTNAARAARGAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGYTNTCNMGNTCNGGNMGNGCNGARACNMGNAGYMGNGCNAARGAR GAYATHAARMGNGTNATHAAYGCNATHGAYAARGTNMGNAARTGGGARAARAARTGGGTN ACNYTNGGNGAYACNTCNGTNACNATHYTNAARTGGGTNCCNGTNACNGCNCARGARAAY CCNGGNGCNYTNMGNAARATHCCNGGNGTNAARACNAARACNTAYTCNAARGCNMGNGTN GARMGNGARMGNGARYTNTAYAAYGCNGARACNAAYGGNGCNYTNMGNGCNAAYTCNCCN GCNGAYTCNACNAGYAAYAAYGCNAAYYTNTCNAAYACNAGYTCNCCNTCNTCNAARAAY CAY------AAYACNGARAARCCNAARAAYGGNACNGTNACNAAYAGYCARGGNTCNGTN ATGTAYTCNGARGARAAYACNCARCARTCNATHGGNTCNTTYGGNTCNGARAAYYTNAAY GARGAYTCNAAYATGTCNTTYCCNGARAAYAGYGGNYTNAGYGARCARGGNGAYCAYAAY GARTTYTCNCAYGAYAGYAAYGAYGCNGAYCCNGGNATGMGNGTNGCNATGAGYATGGTN GGNGAYGARGAR------------------------------------------------ ------------------------------------------------------------ ATGTCNGARAARCAYAAYTTYGGNATHGCNCCNGTNACNTGYCAYGCNTTYAGYAARGAY MGNAAYGGNYTNGCNATGTCNYTNAAYGAYTCNAAYGTNAARATHTAYAARAARGCNGGN AAYAARTGGGAYGARACNGAYACNYTNAGYGARCAYGGNCARMGNGTNACNAGYATHGAY TGGGCNCCNAAYAGYAAYMGNATHGTNACNTGYTCNGCNGAYMGNAAYGCNTTYGTNTGG ATGTTYGARGAYGGNAARTGGAARCARGTNYTNGTNATHCCNMGNATHAAYMGNGCNGCN ACNTGYGTNAARTGGTCNCCNAARGARAAYAARTTYGCNGTNGGNAGYGGNTCNMGNYTN ATHGCNATHTGYTAYTAYGAYGAYGARAAYAAYTGGTGGGTNAGYMGNCAYATHAARAAR CCNATHMGNTCNACNGTNACNTGYYTNGAYTGGCAYCCNAAYAAYGTNYTNYTNGCNGCN GGNTCNACNGAYTTYAARTGYMGNGTNTTYTCNGCNTAYCARAARGARGTNGAYGARMGN CCNGGNGCNTGYAGYTGGGGNACNAARATGCCNTTYGGNGCNYTNATGGCNGARTTYAGY AAYGGNGGNGGNGGNTGGGTNCAYTCNGTNTCNTTYTCNCCNAGYGGNACNYTNGTNGCN TGGGTNGGNCAYGAYTCNAGYGTNTCNATHGTNGAYTCNTCNAARGARAAYGARYTNGTN GTNGTNAARGARAGYTTYYTNCCNTTYATGAGYATHTCNTGGGTNACNGARAAYTCNYTN GTNGCNGCNGGNTAYGAYTGYAAYCCNATGGTNTTYTCNTTYGGNGGNGGNAARATHACN TGYCARGGNAARYTNGAYGTNCCNCARGARAARGARTCNGGNACNATGAGYGCNATGAAY MGNTTYAARAAYYTNGAYAARAARGCNACNGAYAGYGAYAGYTCNCCNGARATGAARACN CARCAYCARAAYACNATHACNCARGTNTCNATHCAYACNGGNGAYAARCARAAYGCNAGY AARATHGCNACNAGYGGNGTNGAYGGNAAYYTNATHYTNTGGGAYYTNAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ACNTGYAGYYTNTGYCCNTGYCCNACNYTN ACNGCNTAYTGGACNAAYCCNCCNTCNTGYCCNMGNMGNGTNTGYTGYGARTCNTCNTGY GGNGCNYTN------AGYTGYTTYMGNGAYTCNMGNACNGTNTCNGTNTTYGTNGCNACN GTNGTNATHACNTAYTTYATHYTNATGGAYATHATHYTNTAYTGYTAYTAYATGAARGCN AAYYTNGTNGARAGYTCNAARGGNGGNGGNGCNGAYGARATGTAYACNCCNTTYACNCAY YTNTCNATHAARGCNYTNYTNAAYGAYCARCCNAGYCARTAYYTNATHGCNCCNAGYACN GARTGGYTNGARTAYTTYACNAAYTTYGCNAARACNTTYTAYTTYATHACNCCNAAYGTN GTNTCNTTYATHCAYYTNATHGTNGGNTTYATHTCNGGNAARTTYGTNTCNTCNGAYAAY YTNAAYGAYMGNMGNATHGGNGTNGTNYTNTTYGARTTYMGNACNTGGYTNGAYGCNTTY GAYGGNACNATHTTYMGNGCNCARCCNGGNAAYCAYYTNAARTAYAAYTCNGTNCAYGCN ACNYTNGGNTAYTAYATHGAYTCNTCNTTYGAYAGYYTNGGNGGNGCNTTYYTNTGYTTY GGNATHTAYTTYTAYATGYTNAARMGNTTYGGNCCNTCNMGNATHCARTGYGGNYTNCCN TTYTGGTCNTCNACNTCNGARGTNCARAAYAARGTNCCNYTNGTNAGYGAY--------- ---GGNGGNAARGARACNCAYTCNGCNYTNTAYYTNTTYTGGAARGCNTTYTCNTTYGGN YTNGTNYTNYTNGTNGGNGCNGGNGCNTGGGAYAAYATHGTNGTNCARTTYTCNGAYGTN TTYCARACNGARYTNAARGAYCCNAGYYTNGCNGCNYTNCARYTNGARYTNTCNCAYGCN AAYACNACNGTNTTYATHTTYCARYTNTGGMGNYTNATHGGNTCNCARTGYATGYTNAAY TAYATHYTNATHATHATHTTYTGYGAYAARATHTGGGARTTYYTNAARGGNACNCARTAY ATHYTNYTNGTNGTNATHGTNAGYYTNTAYGTNATHTCNGTNYTNTAYGTNAAYCARATH MGNACNCARYTNCAYATH------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNGCNAGYYTN CAYTCNCARGGNTAYAARYTNGGNATHGCNTCNMGNACNGGNGCNATHGARGAYGCNGAR GAYYTNGTNMGNYTNTTYGAYTGGGAYAARTAYTTYCAYTAYMGNCARATHTTYCCNGAY TGYAARATHACNCAYTTYAARGGNYTNCAYAARATGAGYGGNATHCCNTTYTCNGAYATG YTNTTYTTYGAYGAYGARCAYMGNAAYATHAARGAYGTNTCNAGYYTNGGNGTNACNTGY ATGTTYGTNCCNGAYCAYGGNGTNACNAAYGARTCNYTNCARGARGGNYTNGARYTNTTY AARACNAAYAAYMGNAARMGNGGNTCNACNTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AAYAAYCARGGNYTNGCNGARAARGTN TTYMGNATHYTNACNAAYCARGAYCCNGARTCNCARGCNAAYGGNATHYTNTCNGARATH AGYGCNGAYGARAARGAYATGAARACNMGNATGGTNYTNGAYATGCAYGAYAARAAYTTY AAYTAYTCNTCNACNTCNAGYTGGYTNGAYGAYGTNAAYCARAGYTTYAAYCCNAAYTGY GAYGTNMGNAARMGNYTNGAYATGTCNGGNYTNAGYTCNMGNGAYTCNAGYTGGYTNTTY ---------TCNACNAARGGNTTYTCNGCNATHGAYGAYGCNAARMGNYTNYTNTCNTCN CARATGGCNAARGCNTCNGARMGNACNTTYAAYCAYAGYATHGAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CARTGGTGYTCNGCNATHAAYTGY TCNAAYAAYMGNATHMGNMGNCCNGAYYTNTCNTTYTTYMGNTTYCCNTCNGARCCNGAY MGNTGYAARAARTGGATHATHAAYTCNCARMGNTTYGAYYTNAARGGNAARTCNTGYAAR ACNYTNCAYAAYGGNAAYACNATGTGYTCNGARCAYTTYGAYAARAARTGYATHMGNGTN AGYCCNAAYTCNGTNMGNCARMGNYTNTTYMGNTGGGCNGTNCCNACNATHTTYAAYTTY TGGYTNCAYTGYAAYGGNTGYTAYTGYCARCCNGARACNGGNGTNGTNMGNTTYTAYATH ACNAAYTGYAGYCAYATHTTYTGYGARAARTGYGTNTCNGARTGYACNAARGARMGNTGY AARGTNTGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGMGNATHTTY AARTGYMGNYTNACNGGNGAYGARATGTTYACNGAYACNTAYCCNATGCARGARGCNGAY GGNTTYTAYGTNGTNAARGGNAARTAYGTNACN---MGNAARGGNGAYTCNGTNGAYGAY AGYYTNATHGGNGGNAAYCCNAGYGCNGARGARGGNGGNGAY---GCNGCNGARGCNGGN ACNGARTCNGGNGTNGAYATHATHATGGAYTCNMGNYTNAARGARACNGGNTTYGGNAAY AARAARGARTAYACNGTNTAYATGAARGARTAYATGGCNAAYGTNYTNACNAARYTNAAR GARACNYTNCCNGARGARAARGTNACNGARGCNAARATHGARGCNAAYGGNGCNTTYAAR GCNGCNYTNGCNAARTTYAARAGYTGGCARTTYTAYACNGGNGGNGGNGAYGAYCCNGAY GGNCAYATHGCNYTNYTNGAYTGGYTNGAYGARGARGTNGAYGGNAARTCNGTNTCNACN CCNTAYATGTAYTTYTAYAARATHGGNYTNGTNTCNGARAARGCNGCNGTNGGNTGYMGN AGYCARAAYGARYTNATHGAYATHATGGAYGGNTTYAARGCNGGNACNTTYTCNATHGGN GAYGCNGARATGYTNYTNAAYGCNTGGAARGARMGNAAYGARGGNGGNAAYMGNGCNATG AGYTTYAARGGNMGNCARACNGCNYTNCAR---------------ACN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNCCNMGNCAYGCNMGNGARTAYGAYGGNGTNGAYAGYTCNGAYYTNGAR GARAARGAYCCNGAYGGNAAYATHTCNGAYGARGAYACNGCNGAYGCNAGYGARACNGAR GARAARACNCCNAARTCNCAYAARCARAGYYTNCCNAAY---GGNAAYCARMGNACNGAR ATHAARGARCARATGTAYCARGAYAARYTNGCNCARATHAARAARCAYATHCARATGYTN GARGARGGNACNYTNCARGARTTYYTNAARMGNACNAARAARATHGAYYTNAAYTAYMGN GARMGNYTNMGNGAYAAYGARATHTGYAARAARGTNGAYATHGARAARGCNGARCARAAY TAYYTNATHGAYTGYGARAAYGCNCARAARGARTTYGARGARAARMGNGTNGCNATGAAR GARAGYYTNATHAAYCAYYTNAARGARAARAARGTNGAYYTNAARGARACNYTNATHTGY GAYYTNAARGARAARMGNGGNGTNATHGARYTNGARMGNCARACNGTNGAYYTNAAYGGN GCNGAYTTYATGGARGTNAARCCNACNATGACNMGNAARYTNMGNMGNMGNCCNAAYGAY CCNATGCCNATHCCNGARAARMGNMGNAARCCNTCNCCNGCNCARGTNAAYATHYTNYTN GAYGAYGAYYTNATHYTNGCNGAYYTNMGNYTNATHATGAARGTNAGYGGNAARCCNATH GCNAARAARCARGGNYTNAGYAAYCAYAGYCCNATHATHGAYACNTCNTCNGAYGTNMGN ATHGARGAYGGNMGNYTNTGGTAYGAYAARAARTGGTTYCARMGNAAYACNATGGTNCAR ATHGAYAAYAARGARACNGGNTCNMGNATHCAYGGNACNATHACNAAYATHYTNAAYCAR GARATHTGGGTNAARAARAGYGGNGAYAAYTCNAARYTNMGNATHATGYTNAAYCARTTY CARAARGGNAARTAYAAYATGAARAARMGNACNACN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ACNATHTGYAARGAYTGG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARACNAARCCNCCNGCNTCNCARACNCCNGTNATHGCNCAYGARATH GTNTCNGGNAARTTYAAYGAYAAYGAYTGGAAYCAYATGYTNGARMGNGAYGGNGGNGAR GARTTYGTNATGGAYATHATGGAYGAYYTNATGGARAARACNATGACNACNATHTAYGAY AARTAYATHGARMGNCARYTNYTNCCNTTYACNATHACNCARGCNAARGAYGCNATHATH GARATHATHGARTGGCARTTYYTNATHMGNGAYGARGGNGARGARAAYATHGARGCNGAY YTNGGNTGGACNCARGAYGARGARCCNGARCCNGCNGARACNGAYTGYTGGGCNCARGGN TCNGTNCCNAARAAYATHATHYTNGCNCCNACNCCNGARYTNGARGARATHCCNGARGAR ACNGARGARGTNCCNCARGARGARGARAAYAARGARGCNCARGARGARGARGAR------ GTNGARGTNTCNCARGARCCNCCNGARYTNGAYGAYATHGTNTCNGARGCNGARGARACN TCNCARGTNGCNGARCARAAYGARAARGAYAARGARAARGARAARATHCCNTTYCCNCCN AARGTNTCNGTNTCNGAYTCNTCNMGNAARAARTTYMGNCCNTAYMGNGGNAARYTNAAR TCNGCNGGNGTNAGYAARATGACNGARTCNYTNGARGARACNGARGTNAARATHATHTAY GAYGARATHGTNGCNTCNATGCCNCCNAGYGARGARMGNCCNAGYACNYTNYTNAAYATG CCNGCNTCNTGYACNAGYATHYTNAARGTNCARACNGGNMGNCCNCCNGGNAAYAARGAY GTNGTNTAYGAYGAYYTNGGNAAYGTNGTNGCNGTNATGAARYTNGAYCCNGARAARYTN CCNACNCAYAARGTNAAYGTNAARTAYCAYGTNGTNGAYCCNGCNGTNGARGCNGCNCAR GCNMGNYTNGAYGCNATGMGNAARGGNAARTCNACNGGNAGYAARATGMGNAARYTNAAR TCNATHAARAAYYTNGCNACNGARTCNGGNTCNGGNGGNTCNAARGTNAARGTNGCNACN AGYCAYAGYTCNGTNGCNCCNYTNCCNCCNCCNYTN------------------------ ---------------------------------ATHGARGARATGGARGTNTCNCAYGGN GTNATHGTNMGNGARGGNGGNMGNGTNAARMGNGGNCCNGGNMGNTAYTAYMGNAARYTN GAYGTNYTNGARGARCAYCARAARGGNATGAARCCNGTNAGYGTNMGNYTNAAYAAYACN GGNATHACNGTNAAYGAYYTNYTNGAYMGNAAYACNCCNATHYTNMGNCCNYTNGCNGAR CARTCNCCNYTNCCNCCNATHATHCCNCARCCNCCNCCNCARCCNCAR---CAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGGAYGARGAYTCNCCN GCNGCNCCNGGNTCNCCNCCNYTNCCNAARAARGGNGCNTAYAAYATHGAYTTYGAYAAY YTNGAYGARTTYTCNAAYCCNTTYGARTCNAARAGYAARGTNCARATGGGNTCNTCNCCN CCNATHGAR---------------CCNAGYACNTTYGAYTTYGAYGARAARGCNGAYCCN TTYGARTCNAARAARTCNYTNGCNAAYTCNCCNCCNGGNTCNCCNAARAAYAGYGTNMGN AAYACNGCNGARATHAGYATGGARTCNAAYCAYGCNGGNGAYCARAAYAAYGAYYTNCCN CARGARCCNGGNGGNGTNCCNGARCCNGCNTCN------GCNGARGARGARAARAGYTCN CARATHACNCCNAARAARAARAARGTNATHAARAARCCNCARTCNYTNTCNAARYTNAAR CCNCCNAARAGYGTNAARMGNAAYAARAAYTGYGARGAYGTNGARATHYTNATGCCNAAR ACNGGNYTNTAYTGGGTNGAYATGGGNYTNGAYTGGMGNCCNMGNTAYCCNMGNTAYTCN ATGACNTTYTAYAARAAYYTNATHCARGAYMGNGGNYTNACNAAYMGNACNYTNGAYTAY MGNGCNTAYCCNGCNGAYMGNGAYACNTTYTAYTAYGGNAAYTTYCCNTCNAAYTTYYTN TGGGGNGTNGCNACNTCNGCNTAYCARATHGARGGNGGNTGGAAYGCNGAYGGNAARGGN CCNAGYATHTGGGAYATHTTYGCNCAYAAYAAYMGNYTNGCNAAYAGYCARACNGGNGAY ATHGCNTGYGAYAGYTAYCAYYTNTAYATGGARGAYGTNAARATGYTNCARTCNYTNGGN GTNAAYTAYTAYMGNTTYTCNATHGCNTGGAGYMGNGTNATGAGYGAYGGNACNATGGGN ACNATHAAYCCNGCNGGNGTNGAYTAYTAYAAYAARYTNATHGAYGCNYTNATHGCNGCN AARATHACNCCNATGGTNACNYTNTAYCAYTGGGAYYTNCCNCARGCNATHGARGAYAAY GGNGGNTGGAARAAYGCNTCNGTNGTNGAYYTNTTYGARAGYTAYGCNMGNATGTGYTAY GARCARTTYGGNGAYMGNGTNAARTAYTGGATHACNTTYAAYGARGCNTTYGTNGTNAGY TGGYTNGGNTAYGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGGMGNATH GCNAAYYTNATHATGGCNGTNTTYTTYYTNYTNGCNGGNYTNGCNAAYACNAAYGAYAAY GAYTGGTTYATHTGGACNCCNATHTAYYTNTTYGCNTCNGTNYTNTGYYTNYTNGCNTTY GCNTTYTCNACNATHATHGGNAAYCAYYTNTGGCARYTNATGATGTCNATHCARYTNGGN GTNGCNATHGTNATGGGNYTNTAYCARGTNTCNYTNGTNTTYGGNGTNGTNCAYAARATG GGNACNAAYCCNYTNGTNYTNGARGARGGNMGNGARATGGGNGGNYTNATHATHATHYTN GTNTGGACNGGNATHTCNMGNTTYTCNCCNTTYAARAGYGCNGGNCCNCARGGNTCNTCN AAYYTNATGACNGGNYTNYTNGCNGTNTCNYTNACNYTNGCNGTNGTNCCNYTNATHACN TGGTCNYTNTGYTTYGTNGGNGAYTGGCAYAARCAYYTNGGNCAYTGYTCNGGNATGYTN ------------------------------------------------------------ ------------AARACNTTYCCNTGYYTNATHTGYGGNAARATHTTYTAYCARYTNTCN CAYYTNCARACNCAYAGYMGNATHCAYACNGARAARATGCCNTTYCARTGYCCNATHTGY GGNAARGCNTTYTCNAARCCNTCNAAYYTNAARATGCAYATHMGNAAYCAYGCNGARGGN AARAARTTYGARTGYCCNACNTGYGGNAARGGNTTYACNCARMGNTCNGCNGTNGARYTN CAYAARAARACNCAYACNGGNGARAARCCNTTYGGNTGYCARACNTGYGGNAARACNTAY GCNCARCAYTGYCAYYTNYTNMGNCAYATHAARATHCAYACNGGNGTNAARCCNTTYGTN TGYGCNACNTGYGGNAAYTCNTTYTAYGARMGNTAYGAYYTNCARATHCAYAAYMGNATH CAYACNAARMGNAARGARYTNAAYTGYCCNACNTGYGGNAARGTNTTY------------ ---TTYGGNAARCAYGTNMGNATHCAYACNGGNGARACNCCNTTYYTNTGYACNACNTGY GGNAARTCNTTYTCNGTNMGNTCNAGYYTNCAYMGNCAYATHMGNATHCAYACNGGNGAR AARCCNTTYGARTGYCCNACNTGYGARAARGCNTTYTCNACNGGNTCNCAYYTNAARMGN CAYATHGGNACNCAYACN------AARCCNTTYGARTGYCARGCNTGYGGNAARTGYTTY TCNMGNAGYTCNYTNYTNMGNGCNCAYTCNAARACNCAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TTYAARTCNTGG GARGAYYTNTGYGCNAARTTYGAYAGYACNAARCCNYTNTCNACNGCNYTNATHTCNGGN TGYAARGARATHATGMGNGTNMGNAAYATHATHMGNMGNYTNATGATHMGNTGYGARAAY ATGTCNCARCARATGGARAARGTNGTNTCNACNYTNACNGARAGYCARCARAGYGARGGN YTNAAYGAYAAYGGNMGNATHGTNMGNCARCCNCARYTNYTNAAYAAYGAYTTYTCNYTN AARCCNTAYCARYTNATHGGNYTNAGYTGGYTNMGNYTNATGCAYGARCARGARYTNAAY GGNATHYTNGCNGAYGARATGGGNYTNGGNAARACNATHCARGCNATHTCNTTYYTNGCN CAYYTNYTNGARGARGARGARGARGGNCCNCAYGTNATHATHGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARMGNGCNAARAARGCNTCNGGNTCNYTNTCNTTYTAYGGN TTYAAYMGNATHTGYMGNGCNCCNAGYATHAARGTNAARGAYGTNGTNTGGGCNTTYAAR YTNGARCAYATHCARCCNAAYATHMGNTCNYTNTAYTTYTCNGCNTCNTCNGARAAYGAR ATGATHAARTGGATGMGNGTNATGAARCARGARATGYTNACNGCNAAYGGNAARACNACN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNCAYACNMGNGARACNTCNAARGAYTGYAGYMGNTCNTAYGTNTGYCCNAARGAY YTNATHCARGARTTYATHTAYCCNGAYTGGGARAAYTGYGAYACNTAYTAYAARTGYTAY MGNGGNGTNYTNAARAARTTYTCNTGYAARACNGGNATHTAYAAYTAYTAYAAYCCNMGN ACNTTYAGYTGYGARGARCARCARTCNGTNACNAAYACNTGYYTNGARMGNYTNACNACN ------------------------------------------------------------ ------------------------------------------ATGGCNGAYTCNAARTCN AGYYTNGCNMGNGAYGGNACNATGCARGTNACNGCNAARGARGGNATHGAYTAYYTNAAR TCNGCNCAYAARGAYACNYTNYTNAARGTNCARGGNYTNGTNAARGAYAARCCNGCNGTN CARMGNGAYGGNACNATGGTNTCNACNGCNAARGARGCNGARMGNYTNYTNGAYGGNAAY AARCCNGAYGCNGAYGCNCARACNMGNGGNCARCARMGNCARATGGAYGAYYTNAARAAY GCN---GARCCNCCNAARGCNAARAARGCNMGNYTNGCNAARGAYGGNACNATGGCNGTN ACNGCNAARGARGCNAARTCNYTNYTNGCNGGNGARAARYTNGGNGAYACNMGNCARGAR ACNAARAGYAARACNGGN------AARACNCCNYTNMGNAARGCNAAYACNATGGCNMGN ACNGTNGARGARGCNAARAGYGTNYTNGAYGGNAARGTNGAYYTNAGYGARGGNMGNAAR ACNMGNTCNCARAGYMGNGGNGAYGCNCCNAARCCNTCNATHAARAARATGGGNACNATG CARCARACNGCNAARGAYGGNAARGCNTTYYTNAARAARAAYAARGGNAARAAR------ ---MGNGCNGTNAARGCNGAYGAYGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AGYACNCCNCCNGAYAGYCCNCAYAAYAGYCARCAYTTYCARYTNAAYCCNAAYAAYGAY GGNMGNGTNMGNMGNACNATHCCNTCNGGNCCNGGNYTNCARTAYMGNTCNCAYAAYTCN AGYGAYTCNAGYYTNGARMGNCAYAGYGTNGAYACNAAYGGNAGYGAYGARGTNAAYYTN GCNCCNGARGCNATGMGNGCNCCNTCNTCNMGNYTNCARGCNCCNAAYAAYAGYACNTCN TCNYTNCCNAARMGNGGNTTYTCNGGNYTNGCNCCNGGNYTNGCNAARCCNCARCARMGN GGNGTNTCNCCNCARMGNCARAGYGGNYTNCCNACNGCNMGNMGNCARATHGCNMGNCCN TCN--------------------------------------------------------- ---------------------------------------------ATGCCNAGYYTNCCN YTNATH---------------------AARCAYACNATGGCNGCNGTNGGNGCNAGYACN GCNMGNGCNYTNAARCARATGATGAARCCNCAYATHCCNATGATHMGNTTYCCNAARMGN GGNTCNCARAGYGARYTNCAR------GCNACNTCNGGNGGNAAYACNAAYTCNYTNGAY GCNYTNYTNACNAAYAAYGTNACNTCNGGNCAYYTNGCNCCNGCNAGYGGNTCNAARAAR GTNAARGGNCCNTCNATHGAYTCNTCNGAYYTNCCNYTNMGNTAYCARMGNAARCCNATH TCNAAYGARGARATHGARTTYATHGARAARGGNGGNCCNGTNYTNGTNGCNTCNATHTTY ------------YTNYTNGTNGCNGCNAGYNNNNNNGARAANNNNCARNNNGGNNNNTGY GTNGARGARTGYAGYATGAAYGAYGAYTCNNNNGGN---AGYNNNTGYCCNNNNGGNNNN GTNTGYGCNTCNAAYGGNTGYGGNCAYACNTGYCARCCNGCNACNCCNGCNCCNAARCCN ---------AARTGYCCNGGNGTNCCNTGYTTYATGTAYTGYAARTAYGGNTGGGCNAAR GAYGCNGAYGAYTGYGAYATHTGYGTNTGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNAAYATHCAYACNCARGTNTCNCCNYTNYTNTTY CARYTNTCNGARAARYTNTGYGGNGARCCNATGAARAARMGNAARACNAARGAYCCNCAR YTNGTNYTNGCNMGNACNCARAARMGNYTNAARAARATHGAYAARGARATHAARMGNYTN TCNMGNTTYGGNAARACNATGAARCCNGTNGARGARATHGARGTNGAYMGNMGNAARYTN ATGTCNACNGGNGARMGNMGNMGNGARCCNAARGTNYTNACNTTYGARGARTCNGARTCN MGNGCNYTNYTNCAYAARGCNTGGACNTCNTAYMGNACNAGYTGYCAYCAYGARYTNYTN AARACNTTYACNYTNGTNTCNGCNGCNCARCARGARGCNYTNGAYGARYTNMGNGCNGAR TCNGARGARYTNTAYCARGCNGCNATHCARAARGAYGARAGYATHYTNCCNTTYACNTTY GARGGNCCNAARGARACNCCNCCNATHAARGAYTAYGAYGCNCCNGAYGGNGARTAYATH GAYACNACNMGNAARTTY---------------GAYGTNGARTGGAAYATHGAYATGGAR GTNAAYYTNTTYCAYGCNATGMGNGGNCAYAARCCNGCNGGNGTNAAYMGNCAYTTYCAR ATGATHGCNATHCAYGAYAARYTNAGYTCNTCNACNAARAARGTNACNTCNAGYGAYGTN TGGAARCAYYTNTCNACNYTNTAYGAYYTNCARGCNYTNTAYGARTCNGARATHGTNCCN TTYCCNAAYAARAAYGGNGAYTTYGCNYTNGTNGAYMGNGARATGYTNGAYYTNTGYACN MGNTCNTTYCCNMGNTCNTCNTAYATHAAYGCN---CCNAGYGARCAYGCNAARCCNGAR GCNGGNAARACNATHTCNAARTTY---AGYACNAARCARGAYAGYAARCARGTNTCNCAY ACNCCNAARTCNGAYGCNAARAGYGARCAYAAR---TCNTCNAGYAGYTCNAARTCNGAY AGYMGNTCNAAYACNCCNTCNAGYMGNTCNGARTCNAARTCNTCNCAR---CAYAAYAGY AGYAGYGCNGCNACNAGYCAYTCNAARTCNTCNCAYCARAGYACNCCNACNTCNGCNCCN TCNCCNTCNCCNAARMGNACNAARMGNACNMGNAAYGTNAAYTCNGCNTCNGCNAGYCCN GCNACNCCNACNGARCCNCARTCNAARMGNMGNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARTCNACNAGYACNAARCARAAYGARCAYCARYTNCAR CARCARCARCARYTNYTNCARATGAAYATGAARAGYCARCARGAYAAYAAYATHGTNGAR CARYTNAARYTNATHGCNGCNCARAARGARTCNCARGTNAARATGYTNGARATGGARYTN GCNCARYTNMGNAAYGCNCAYTCNCAYTCNAARCCNCCNCARGCNTGGGCNGAYCARGGN TCNGARACNGTNACNTCNGGNTCNGTNACNCCNGGNCCNCCNGARGAYGCNATGACNGGN GTNGGNGTNACNTAYMGN---MGNGARACNACNCARAGYGCNMGNTCNAGYGCNMGNTCN YTNTCNMGNATGTCNAGYCARGCNACNCCNACNCCNGGNGARCCNMGNGCNCCNACNCCN TCNAAYACNAAYGCNGCNAAYCARAARGARATGGARAAYYTNMGNTAYCARATHCARGAR YTNACNGTNATGTCNAARGCNGTNGARGTNGARMGNGAYAARATGACNGARYTNGTNCAR GTNYTNCARACNMGNYTNACNGARGARGTNGAYMGNCAYAAYAARACNCARCARGARYTN CARGGNCARAARMGNACNGGNATHGARYTNGARAARYTNYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR ATHCAYAARGCNGARATGGARCARTAYMGNGCNAARCARCARMGNGARAARCARGCNATG YTNGCNMGNYTNCARGARAARYTNCARCARMGNYTNGARGCNGCNGAYGARAGYGARGCN MGNGAYCARAARGARCARGARCARYTNAARGARCARCARATGGCNACNYTNGAYAARGTN YTNGCNACNAAYYTNGAYYTNACNGAYGARGCNAARGARMGNATHATHMGNGARCAYGAR CARAAYATGCARGCNYTNTCNAAYCARYTNATGMGNAGYAARGTNMGNCARCARAARAGY YTNGARATHAARYTNAAYCARMGNAARGCNAARYTNGCNGARYTNAARCARAARCARYTN GCNGGNGCNMGNCCNGGNAGYAGYAARAARGARAARGARAAYATGGCN------ACNAGY ------YTNGAYGARCARATHGCNAARGARGARGCNGGNTTYGARGAYGCNMGNCARGCN GCNGTNGCNGARYTNMGNAARCARYTNTCNCARGARACNGARGARTCNYTNAARCARCAR GAYGARGARATHGGNCAYYTNATHGGNMGNYTNCARGTNGGNCARGCNMGNMGNAARGCN ATHATHCARAARCARGAYGCNGTNYTNAARGAYYTNCARGAYAAYYTNGARMGNCARGTN ACNTCNGCNAGYGGNYTNMGNCCNTCNACNACNGAYCARATHYTNAAYCAYCAYTAYGCN AARGTNTCNCAYYTNAAYGAYCARYTNCARMGNCAYMGNGAYGAYCAYGARMGNMGNATH YTNGARAARYTNACNCARMGNMGNGCNGARAARGARCARGARATHGARTCNCARYTNGAR CARGARGCNCAYACNGARTAYTCNGARAARCARAARMGNGGNGCNGGNTAYGCNAGYYTN GCNYTNATGCARTCNTTYYTNGARCARMGNCAYAARAARGCNYTNCARGARYTNGARYTN GARATGAARGCNGARYTNGARAARAGYAARAAYGAYYTNAAYCARCARYTNGARGTNGAR YTNMGNAARGARYTNGAYGCNGARMGNCARAAYYTNYTNACNCARYTNGCNGCNGTNAGY GAYATHTCNCARTCNGAYYTNCARAAYGCNGTNACNGCNNNNACNAARGGNCARACNGAY TCNAARGTNGCNAARMGNYTNGCNAARGAYYTNAARGAYAAYGTNGARMGNGCNMGNTCN GCNATGTCNGTNCAYMGNGARGAYCCNMGNGAYGARGAYGTNGGNTAYMGNMGNAGYAAY ACNGAYYTNGARAGYMGNCARCARTAY------AARAARGGNMGNAARGGNTCNGCNGTN TCNATGCARMGNMGNGGNAGYGCNMGNCARGCNTTYGCNGAYGARGAYGARTAYGAY--- ATGGAYATHYTNTAYTTYTCNYTNTGYGTNTTYGCNYTNTTYGCNTCNTCNTTYGGNCAR GAY------GCNYTNGARGTNACNTTYGARAAYGCNACNMGNGTNGAYGCNGTNGARGGN TCNAARYTNATHCAYTTYMGNTGYCAYYTNAAYMGNGGNGCNATGTAYGTNATHAAYAAY AARGTNGAYATHGTNCAYGTNCAYCCNYTNACNAARGAR------------------GAR ACNATHYTNAGYAGYGCNGCNGAYYTNGTNGARGGNAARCCNTCNTTYTAYAGYGTNAAR ATHGAYCARAAYCCNCARGAYCCNACNTCNATGGTNYTNGAYTTYACNATHYTNTCNGTN MGNTAYCARGAYGAYGGNATGTTYAARTGYCAYGTNCAYCCNGGNGGNAARTCNACNTCN ACNGARGARGGNTTYGCNGARMGNGARGTNGTNGTNCAYMGNCCNGTNTCNTCNYTNAAR YTNAARYTNGGNGAYTTYGAYGCNATHGARGAYTCNCCNACNGAYCAR------------ YTNCARATHGAYCAYGGNGARTAYAARATHGCNTGYATHGCNGARGGNAGYAAYCCNGCN ACNGARGAYGTNACNYTNTTYTTYCAYGGNGTNGARYTN---GAYCARAGYACNCCNATG GTNACNACNATGGARGGNTCNGARMGNATGTTYAARACNGTNGTNAAYGGNAGYYTNAAY ATHGTNGTNAGYAAYTCNGGNCARGARYTNGTNTGY------CARTCNACNGAYTCNACN GGNCARTCNAARTCNGTNACNYTNGGNATHAGYGTNAAYATHTAYGAYCCNGTNGTNCAY TGYAAYGAYAGYGARGCNCAYYTNGGNGARGAYAAYCCNGTNYTNTTYTGYACNGTNAAY CAYACNGGNYTNGARGTNGARGGNTAYTCNTAYCARATHGGNGAYACNGGNGARATHGTN AARGCNGGN---------GARAAYCAYCCNAARAAYATHATHGTNGCNGTNTCNGAYGTN TCNCCNGGNATHTCNGTNGTNTCNYTNGAYYTNCAYAARGCNGARCARCARTAYYTNGAY AARAAYTAYTAYATHYTNATHGAYATGAARGGNGGNCAYACNAGYAARGARTCNGTNMGN YTNAGYAARAARGAYCCNCCNGTNTCNGARAAYGGNAAYGGNAAYGGNGGNGAYGGNGGN TCN------GGNGARGCNACNYTNAGYTGYCCNGCNGGNAGYGTNATHAGYGTNTCNGAY GCNYTNYTNGGNCARAAYAARTGGTTYGARTGYGTNYTNACNGARGARGAYTGYACNCAY TCNACNCARATHTTYMGNTCNTGYGARGGNYTNAAYTCNTGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TTYYTNAGYATHGCNATHGAYTCNGGNYTNGTNAARCAYMGNGGNTTYGAYTTYMGN ------TCNCARAARYTNCAYAGYATGGCNAARGCNYTNAGYCCNTGYGAYTTYMGNYTN GGNGGNACNAAYGCNGAYTTYYTNACNTTYGAYCCNGAYGGNAARGARTCNCCNTCNTCN TCNCARAGYGCNGTNTCNTCNCARATHGAYGAYACNATHYTNGARAAYGARYTNYTNTAY CARGAYCCNAARGARGARGGNAARGTNYTNACNAAYTTYACNATGACNGGNCARCARTGG GAYCAYATGGTNAARTTYTTYTCNCARGCNGGNTGGTCNGTNATGTTYGAYTTYAAYYTN TTYAARTGGAARAAYGGNYTNTGGGAYCCNAARAAYGCNGARGAYYTNYTNMGNTAYTCN GCNYTNMGNGGNTAYGAYYTNCARGCNTTYCARYTNGGNAAYGARCCNAAYTCNTTYTAY TAYAAYTTYAAYTTYAGYATHCCNGCNGCNACNYTNGTNAARGAYTTYAAYATHYTNMGN GAYATHYTNTAYCARTAYCCNCARTAYATGAARAAYAARYTNTAYGGNCCNGAYGTNACN GAYYTNTAYMGNCAYTCNTCNTCNMGNCARTAYYTNCARGAYTTYGTNGCNGCNGGNGGN AGYYTNGTNGTNGAYGARATHTCNYTNCAYCAYTAYTAYYTNAAYGGNMGNYTNGCNAAR GCNGARGAYTTYTAYAAYATHGCNGTNATGGARAARYTNMGNTAYGARATHGARTGGGGN CARACNTTYGCNAARGGNAGYCCNATHMGNYTNACNGARACNTCNTCNTGYTTYGGNGGN GGNGCNCCNGGNYTNTCNGAYGCNTAYGTNGCNGGNTTYYTNTGGYTNGAYAARYTNGGN YTNGCNGCNAARTAYGGNGTNACNMGNGTNTTYMGNCARACNTTYTAYGGNGGNAGYTAY GCNYTNYTNTCNCCNAARYTNGAYCCNAAYCCNGAYTAYTTYYTNTCNGTNYTNCAYAAR CAYYTNATHGARGGNCCNGTNTTYAAYGCNACNGTNCARCCNAGYACNCCNCARTTYMGN ATHTAYGCNCAYTGY---ACNMGNAGYTTYGGNATGTAYAARAARGGNGCNYTNACNYTN GCNTAYYTNAAYACNAARAAYGARACNGTNACNGTNGGNYTNAAYCARTTYTCNTCNYTN AAYGTNGAYYTNTAYATHYTNACNCCNGGNGAYACNGCNGGNYTNMGNTCNAARTTYGTN AARYTNAAYGGNGARGTNYTNAARATGTCNGGNTCNTCNYTNCCNCCNYTNACNCCNAAR CCNTAYAARGGNGAYATHGCNYTNCCNCCNYTNTCNTTYGGNTTYATHGTNGTNCCNAAY GCNAARGTNGCNYTNTGY------------------------GAYATHAGYCARYTNTTY GGNGCNGARGAYGTNGAYTAYMGNAAYATHAAYAARACNGTNACNAAYATGYTNCCNCCN CCNCCNATGCCNTCNGCNGTNYTNYTNTCNCCNTCNATHAARAGYAGYACNCARGTNGGN TGGAGYCARTTYAARGARAARCAYCCNGAYGAYTTYGTNCARGARACNGARMGNAARMGN YTNMGNGAYGCNCARATGCARGAYGCNCARGAYACNGAYYTNMGN--------------- CARTCNTCNTCNCARYTNMGNATGATGAAYGTNGTNCCNAAYCARCARCCNGTNGGNTCN AGYMGNGAYAARATHATGCARMGNGCNGARGTNGARGTNAARGARGGNMGNATGACNAAR GARGAYTAYCARGTNYTNGTNMGNCARGTNGGNGARGTNTAYGAYMGNCCNMGNGCNMGN GARGGNCCNGARGCNTCNMGNATGYTNATHCAYGAYCCNMGNATHMGNGGNAGYMGNGAY AGYMGNYTNTCNGARTCNTCNGAYCCNGARCCNMGNMGNYTNGGNGGNAARMGNATHGTN CCNGARYTNMGNMGNGARMGNAGYGAYMGNGARCAYTCNCCNYTNTAYCARGAYGARMGN GAYGGNTAYMGNYTNGARMGNAGYMGNGGNAARGAYACNGAYCAYATHMGNGGNTAYMGN AAYCCNGTNMGNMGNMGNCCNGAYTCNCCNCCNGAYMGNTCNGAYMGNGGNMGNCAYCAY GARGARGAYCCNGTNTAYCARATGCCNGAYGTNGAYMGNYTNCCNMGNGGNCCNYTNMGN GARGGNGAYAGYGGNGGNGGNCCNGTNGAYGCNGAYATHGAYTTYGGNMGNAAYATHCCN CAYACNGCNCARCCNMGNCCNTAYGARGCNGARGTNATHGGNCCNMGNMGNAAYTCNGAR GAYMGNCCNTAYGGNGTNACNCARCCNACNCARMGNYTNMGNYTNCCNGGNATHAAYAAY GCNGCNCCNACNGTNGTNGGNCCNMGNCCNYTNCARCCNGGNGGNCCNYTNCCN------ ---------------GTNATHCCNGCNTCNGCNCCNAAYCCNCCNGCNGTNCARCAYGTN AARATHTCNGAYCCNYTNAGYGAYCCNMGNTGGTCNGCNATGAARGGNYTNYTNGAYGCN GGNGGNACNGARGARGTNGTNYTNGAYGAYAARCCNTTYGARYTNMGNATGGGNACNGCN MGNAARYTNMGNYTNTAYAAYCARGTNTTYGAYGTNMGNGTNGAYYTNAARGARMGNGGN ATHTGYATHAAYGGNCAYYTNCARTAYAARYTNGGNGARCCNATHAARGARGTNAGYATH AAYGGNMGNCAYGTNMGNYTNTAYTAYCAYGGNYTNCCNAARCCNATHTGGYTNGAYGGN CARTAYCAYGARATGMGNYTNGAYGCNCCNCCNMGNAAYGTNYTNGTNGAYGGNTGYATG MGNGGNTTYCARATHGAYGGNMGNGAYAAYATGATHYTNGTNGAYMGNATHGARAARGGN CCNTAYGGNGGNCCNCCNMGNAARATHMGNATHGTNGGNGTNGARCAYGARATHAGYTTY AARTTYCCNCCNMGNACNATHYTNATHGAYGGNAARCCNTGYGARYTNAARYTNGAYAAY AARATHCCNTTYGTNATHATHGARGGNAARCCNCAYGGNATHMGNTTYGARGGNGARCCN MGNACNATHTTYATHAAYGARCARCCNTTYACNATHCCNYTNGAYAARGCNGARAARATH MGNATHGGNCARMGNCCNACNTAYATHGCNTTYGGNGGNCCNGCNCAYGARATHATHATH GAYGGNAARTGGTTYGARGTNAARTTYGAYAAYACNYTNAARGAYATHCAYYTNGGNAAY MGNCAYTTYMGNATHMGNATHCCNGGNCCNYTNCCNMGNGTNAARATHYTNGAYCARYTN CCNATHAAYTTYGAYGTNTCNMGNYTNATGGTNAARAAYTCNATGGARGTNCARMGN--- GARATGCCNTCNACNATH------------YTNCARCCNACNATHCCNGGN---GGNGGN CCNCARMGNYTNGGNCCNATGCCNGTNCARAAYTCNATGGTNGCNGGNCARACNCARATH CARCARCCNCARATGYTNMGNCCNATGCARCARCCNCARGTNACNCARGCNAAYCCNAAY MGNCARYTNCCNCARATHATHCCNGGNYTNCCNGGNGTNCAYGCNGGNATHGTNCARCAR CARCARTCNAAYACNGGNATHACNYTNCCNGGNATGGTNGGNCCNCARCARCAYYTNCAR ACNATGGGNGTNGGNGGNCCNYTNCAR---------------------------CARGGN GTNGTNAAYCARGTNCAYAAYACNGGNATGATHGCNCARTCNYTNCCNGGN--------- ---------------------------------------------GCNATHCCNGGNGCN GTNMGNCCNYTNATHCARGCNTCNAAYGGNCARCCNGTNCCN------------------ ------YTNGTNACNGGNATGCARGGNTCNGTNATHAGYCCNAAYACNGCNATHTCNGGN GCNYTNTCNACNACNGGNAAYATHYTN---------------------GCNGTNCARAGY TCNGCNTCNTTYGCNGCNGCNGGNACNGTNGTNGGNGCNYTNCCNCARACNAAYYTN--- ------------------GCNGCNYTNCCNTCNTCNYTNTCNGCNACNYTN--------- ---------TCNYTNGCNACNGGNYTNTCN------------------------------ ---------------------------------------------------------YTN CCNGGNATGTCNGCNGCNCCNCCNCARAAYAAYACNAAYACNACNACNTCNAAYGCN--- ------------------------ATGGAYATHAAYAGYYTNYTNAGYAAYYTNATHAAR GCNGGNYTNATHAARGAYTCNAARACNGARGAYAAYGCNCCNGCNACNAARCCNCCNCCN GCNGARGAYATHAAR------CCNAARAARAARATHMGNAARCCN--------------- ------------------AARGGNGTNATHCCNAAYYTNTCNGAYTTYGAYGCNGAYYTN YTNAARATHTCNTAYCARMGNGTNGTNGAYGARYTNCAYGARGGNATHCARTGYCAYACN TGYTCNGCNMGNTTYACNGAYGAYGAYCARGARAARTAYMGNGCNCAYYTNGAYTGGCAY TTYMGNCARAAYAARYTNGARCARGARATGGTNAARGTNGCNAARAAYMGNAARTGGTTY TAYACNATHCCNGAYTGGATHCARTAYGARGARYTNGARGAYAGYGARGARAARTCNMGN AGYGARATHTTYGARCARATGMGNYTNGGNAGYGARCARTCNGGNTCNGGNGTNTTYGCN ATGGAYCCNCARMGNYTNMGNGCNYTNGARGGNAARGAYGTNGTNACNAAYCCNGTNTCN ACNGGNGCNGARGGNGARGAYGTNTGYGCNACNTGYGGNGAYCCNTTYGAYTCNGTNTGG AAYGARGARACNGARGARTGGATHYTNAARAAYACNATHAARGTNAAYGGNAARACNTAY CAYCCNATHTGYTAYGARGAYATGCARGARACNCCNACNCCNGTNGCNGAYYTNGTNAAR AAYCCNYTNGAYACNGARATHCARCARCARCARCARCARYTNGAYATHAARCCNGAYATH AGYATHAARCCNGAYATHAARAAYATHGARATHAARCCNGARTCNAGY------------ ------GAYACNGGNGTNGARGTNAARAARGARATHATHGARGARCCNGGNAAYGCNGTN CCNTCNGARCCNTTYATHAARTCNAARGGNGAYATHCCNGGNATHTCNTCNGAYYTNACN GAYAAYAAYGARAARTCNGARGARGTNTCNGCNAARACNGGNGARTAYTCNAAYYTNAAY GARAGYGARATHCCNACNTCNGCNYTNAAYAAYCCNGGNCCNAAYTCNATHMGNAARGTN ATHTCNGTNTGYCARGARGAYCCNAAYTCNCCNTGGGARATGGAYTCNAAYCCNACNCCN GARYTNTCNMGNACNCCNAGYCCNYTNCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CAYGCN YTNTAYTCNAAYTTYAARATHGARGGNGARMGNGAYMGNTAYMGNYTNCAYGTNTCNGGN TTYTCNGGNAGYGCNAARGAYTCNYTNATGMGNCAYAAYAAYAARCARTTYAGYACNGAR GAYMGNGAYCAYGAYAAYMGNMGNGAYGCNAGYTGYGCNAGYGARTGGGARGCNGGNTGG TGGTTYGAYAARTGYTGGTAYGCNYTNYTNAAYGGNCCNTAYCARAGYGAYGTNMGNTAY AARGGNATHGCNTGGAARAGYTGGAARTTYGARCARYTNMGNGGNGCNGARATGAARATH MGNCCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARACNACNTTYAARCCNGAYAARGARGARYTNGARGAYAAYTTYGTNYTN TTYGCNTTYTGYACNTTYATHGGNATGGARGAYGTNAAYYTNGAYGTNCARAAYYTNAAR TCNYTNATHCARTAYMGNTGYMGNTGYAARTCNAARAARGGNTTYGCNTAYMGNTCNTGY ACNYTNTAYTAYTGGYTNTGYCCNMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TAYTCNTCNTCNATHGGNGTNCARTCNCARCCNGCNTCNATGACNGGNYTN AGYGCNGCNCCNATHTCNAAYCCNAGYTCNTCNCCNMGNCCNAGYATHYTNMGNAARMGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TTYATHMGNGCNTCNTAYYTNMGNMGNTTYGARCARAGYCCNGTNCAYMGNGGNACNCAR GTNAARACNYTNGCNGARACNAGYATGACNTGYGTNYTNGAYAAYYTNGARATGTTYGAY YTNGARGARTTYCARGAYGARTAYATHATHAARACNATGATHCAYMGNYTNAARMGNAAR MGNGCNGTNACNAAYAARGCNYTNTCNGTNYTNTTYGTNCCNACNATHACNMGNATHGAY YTNGARGGNATHTAYYTNACNAAYAAYACNATGMGNATGYTNTGGACNCARTGYCCNCAY YTNMGNGGNGTNAGYYTNAARAAYTGYGGNTAYATHATHACNGAYGTNATGYTNACNCAR YTNGCNAARAAYYTNCCNAARYTNGARCARYTNAAYYTNAGYMGNTGYTCNCAYYTNACN GAYAARTGYYTNGCNATHATHTCNAARMGNYTNACNCAYYTNAARGTNYTNCAYATHGCN GGNGTNCCNTCNATHAARCCNACNTCNGTNCAYACNTTYYTNAAYTCNGCNAARGARYTN ACNTTYYTNGAYATHTTYTAYATGAARACNACNGARGARGARTTYTCNTCNYTNATGGAR AARGCNGCNGARYTNAARGTNMGNYTNATHYTNCAYTCNCCNAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNCCNTAYYTNGGNAGY AARATHAGYYTNGTNTCNAARGCNGARATHMGNTAYGARGGNACNYTNTAYACNATHGAY CCNAAYGARGCNACNGTNGCNYTNGCNAARGTNMGNTCNTTYGGNACNGARGAYMGNCCN ACNGAYMGNCCNYTNCCNGCNMGNAAYGARGTNTTYGARTTYATHATHTTYMGNGGNCAY GAYATHAARGAYYTNCAYGTNTGYGARCCNCCNAARCAYTGYCAYGARAGY---GGNGTN CCNCCNGAYCCNGCNATHGTNAARTCNTCNCARCCNCCNCCNGGNCCNTCNGGNGCNGCN TTYCAY------CCNGGNCARGCNGGNTCNGGNAGYGGNCARCAYTAYCARCCNCARCCN YTNTTYTAYAAYCARGGNGGNCARGCNGCNCCNGGN---------TAYCCNCCNCCNCAY CAYGGNCAYTCNGGNGGNTTYCARGARGAR---------GTNGARCARTCNCCNGARCAR ATHGTNCAYGGNTCNGCNGCNGCNTTYGGNGCNMGNCCNATHTCNGGNTCNCARACNTCN ACNCCNCCNCCNAGYMGNAARTCNCCNACNTCNGAYCARGGNGTNCARGTNCARCCNMGN AGYCCNGARAARTCNAGYAAYGARAGYAAYCARCAYAARCCNCAYAGYCAYCCNAAYCAR CARAAYCAYCAYCAYCAYCAYCAYCAYCAYCARCARMGN---GARTAYCCNMGNGGNGGN ATGMGNGGNGGNCAYMGNATGGAYAAYMGNAAYGARGGN---------MGNCCNAAYGAR GCNMGNGGNGCNATGTCNTCNTTYGTNMGNGGNMGNAGYAGYAAYMGNGGNCARCAYATG MGNGARGGN------GGNACNGTNMGNGGNCARGGNCAYCCNMGNCAYMGNGGNMGNGGN GGNMGNTCNTCNGARCCNYTNAARTTYGAYACNGAYTTYGAYTTYGARACNTCNAAYGCN CARTTYGAYAARGAYCAYATHGARAARGARYTNAARAAYYTNAGYYTNAGYGAYAARTCN ATGAAYGGNGAYAARACNGAYGAYGAYCCNGARATHGARGARGARGARGGNGARGARGAR GARGAYGARACNGTNTAYTAYGAYAARAARAARTCNTTYTTYGAYAAYATHAGYTGYGAR GCNACNGARAARAGYAARGGNCARMGNGTNACNTGGMGNGARGARMGNAARYTNAAYAGY GARACNTTYGGNATHTCNGARAAYTAYMGNMGNAAYTTYMGNGGNMGNGGNGGNTGGMGN ------AAYCARMGNGGNTGGMGNGGNGGNMGNGGNMGNGGNGGNGGN------------ ------------------------------------------------------------ ------------------------YTNATHYTNGTNCAYACNAAYGTNYTNTAYTCNGAR GTNATGGGNGARGCNATHCAYYTNCCNTGYYTNAARAARYTNGTNTTYCAYGAYYTNCAY GCNAAYYTNYTNGAYCAYMGNCAYGARAGYMGNMGNATGTAYAAYAARMGNGTNACNATH CARGTNTCNCARCAYTGYACNAAYYTNGARTGGGTNGARYTNTAYACNATHTGGGCNGAY YTNGAYGAYGAYGTNGTNCARCAYTTYACNAARAAYTGYCCNAARYTNMGNMGNYTNTTY YTNACNTGGTCNACNCAYYTNACNGCNTCNGGNTTYGTNAAYACNATHGCNTGYTCNAAY ATHACNCAYYTNGGNYTNGGNGAYMGNCARGARACNGARCCNTAYYTNAAYTTYGTNYTN CCNCAYTTYCCNCAYYTNATHTCNYTNATHGTNAAYGGNMGNGAYGTNCAYTCNAAYGAY TGYATGGCNYTNAGYAAYTTYTGYCCNGCNYTNCARGARYTNGTNTTYGARYTNAARTCN ATGMGNGAYCAYGAYTGYYTNTTYGAYTTYTAYYTNCAYCARCAYAAYTCNYTNTCNGGN YTNAAYYTNCARCARATHGTNGARGGNTGYAARCARYTNMGNAARATHCAYGCNCCNTGY TCNAARGTNGAYGAYGARAGYATHGTNAARYTNTCNYTNAAYTGYCCNYTNYTNGARGAY GTNAAYTTYATGCAYTGYCCNYTNYTNACNGCNCARTCNYTNATHGCNYTNACNGARAAY TGYCCNCARATGAARTTYGCNAAYTTYCARCAYACNTTYAAYCCNCARGAYTTYYTNYTN GARTTYYTNCARAARTGYCCNYTNYTNCARGARATHAAYTTYGAYATHACNTAYTCNCCN ACNCAYCCNCCNGTNAARTCNTCNTGYGGNTGYAAYTCNYTNTTYYTNATGCARYTNATH GARATHAGYAARTAYTCNAARAAYYTNGARATHYTNTCNGTNYTNTAYAAYMGNAAYYTN ACNCARATHGGNGTNTTYTCNATHTTYMGNTCNYTNGAYYTNTCNYTNMGNAARYTNMGN TCNTTYAGYTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYTAYCCNGCNGARGTNGAYGTNTCN TAYGAYGARTTYAARTAYGTNGARCARATHYTNCCNAARGCNACNGTNCCNGARATHCCN CAYCAYTCNTCNTAYCCNACNCCNTCNGGNTGGGTNCCNCCNAAYGAYGAYATHMGNTCN CARCARCCNTAYYTNGTNMGNMGNACNAARAAYCAYGTNYTNCCNGTNTAYCCNGGNTCN MGNGARGTNTGGAARMGNATHAARCAYCAYGTNGTNATHAARAAYATHGARGGNGAYATH TGGAARYTNGARTCNGARYTNTGYAARCAYYTNCARGAYACNACNGARACNGAYAARGTN ATHACNCARGTNCAYGARGTNAGYMGNTGYATHMGNATHMGNGGNGARCAYMGNGCNGAR ATHGCNCARTTYYTNYTNGAYAARGGNATG------------------------------ ------------------------------------------------------------ ------------------------------GAYCCNMGNATHYTNMGNTCNMGNYTNATH AARGARYTNCARGCNAARTGGAARGAYGGNATHATHTAYGGNAAYATGGGNTAYTAYTCN GGNGCNATHTGGYTNMGNATHCAYTTYGAYATHTCNCARMGNMGNMGNAARAAYTCNGTN ATGAARGGNMGNTAYAAYCCNAAYAAYTCNGTNTTYATHYTNCAYTTYCARGGNTCNCCN TAYYTNATHATGAGYAAYTCNMGNGCNAARGARACNACNYTNATGACNCARTCNYTNATG ACNGTNTTYAAYGCNGCNAAYYTNACNTAYATGCARYTNTTYGAYMGNCAYGTNTTYTCN YTNGCNGAYATHGCNYTNAARCARAGYCAYGARACNTCNGCNGTNCAYMGNTTYAARGAR GTNGAYGAYAAYGARAAYCCNYTNTCNYTNTGYGAYMGNAARMGNAARCARGARGGNGAY ATHTTYCARGAYACNGARGAYATHGTNGAYGARAAYMGNAAYGARAARCAYATGMGNCAY GTNTAYGTNGAYAARAARTTYGGNCCNGGNAGYCARCCNCCNYTNGARAARYTNGARTAY AARTTYAGYATGGGNTTYCAYAGYCARCARAAYYTNAGYGGNGAYTGYAARACNMGNGTN AAYATHAARGGNATHTCNGTNYTNAAYGGNYTNMGNCARYTNGCNAAYAARAGYTAYATG ACNTTYCCNYTNCCNMGNCAYYTNACNGGNGTNYTNGCNGAYAARMGNAAYAGYTTYACN GTN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TCNTGYATHCARACNMGNAARTCNAAY YTNAGYCCNTAYYTNGTNTTYGAYGTNYTNGAYGGNATGGARACNTCNGGNAGYAGYGGN TCNAARTCNAAYAARAARGARGCNAARTGYGTNTCNYTNYTNTGYAARAAYGTNGTNAAY YTN------YTNACNAARAARAAYACNTCNTCNGARMGNCARAARAARATHGGNGTNATH TGYCCNTAYACNGAYCARAARAARGCNATHCARGAYAGYYTNGGNGARYTNAAYYTNTAY AAYATHYTNGTNAAYACNGTNGAYAGYTTYCARGGNCARGARAARGAYATHATHATHYTN TCNTGYGTNMGNGCNCARGGNAGYCAYCARTCNGTNGGNTTYGTNGAYGAYAGYAARMGN ATGAAYGTNGCNYTNACNMGNGCNAARYTNGCNYTNTAYATHGTNGGNCAYMGNAARACN ATGAGYACNTCNGAYYTNTGGAARYTNYTNTAYGARGAYGCNGGNAAYMGNMGNTGYYTN GTNGARGTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARATHTTYAARCCN ACNGTNATGTCNGCNAARAAYATHAAYTTYGAYTTYTCNAAR---CCNYTNACNGARGCN GGNAARACNCCN---------------------AARTCNAARGCNGTNAAYACNCCNTCN MGN------AARYTNGTNCCNACNTCNTCNAARYTNGCNTCNACNAARAARGGNACNCAY ACNACNCCNTTYAARTTYACNGGNAAYTCNAAYACNACNGTNACNYTNAAYTCNACNATG ACNTCNTCNAARAARCAYACNTTYGAYYTNAARGCNAGYYTNGCNAARCCNYTNACNTGG AARCCNCAYACNGGNAARYTNCARCCNGTNGARCAYAAYACNAARGCNCCNGTNCCNMGN TCNGCNGCNAAYGTNACNTCNCARAAYMGNGTNMGNAAYGTNYTNAGYMGNGAYTCNGCN AAYAARATGMGNCCNGTNCARGCNAARAAYGTNMGNMGNGCNGCNCARYTNGAYMGNMGN AGYAAYCARAARTAYGTNGAYATGATGAARMGNMGNGGNYTNATGGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGGAYTTY GGNTCNAARTTYGTNTAYYTNGGNAAYGARCARGARGAYGARGARGARGTNAARGTNGAY GARGTNGAYGAYGTNGCNYTNTCNAAYAGYGAYTGYAGYGAYGAYGAYGGNGARACNTGY YTNYTNGAYATHYTNGAYACNGCNGGNCARGARGARTAYTCNTCNYTNAARGAYCARTAY GTNMGNGAYGGNGAYGGNTTYGTNATHATHTAYAGYATHGTNGAYGARGARAGYTTYAAR GARGCNAARGCNATHTTYMGNTGGYTNAARMGNYTNMGNGAYGTN---AAYTGYCAYGCN ATHYTNGTNGCNAAYAARCARGAYYTN------AARGAYGARGCNAARGTNAGYAGYCAR GAYGGNAARGAYYTNGCNAGYGARYTNGGNATHCCNTTYTAYGARACNTCNGCNAARGAY GGNTCNGGNGTNGTNGAYGCNATGAARGGNYTNGTNMGNATHATHCCNMGNACNGAYAGY GAYTAYAARATHGTNATGYTNGGNAGYGGNGCNGTNGGNAARTCNAGYATHACNYTNMGN TTYGTNAAYAAYGTNTTYGTNGAYGAYTAYGAYCCNACNATHGARGAYTCNTAYMGNAAR ATGATHTCNGTNGAYGGNYTNTCNGCNGTNAGYAARGAYACNMGNAARGCNTCNAARATG GCNAARMGNTCNAARAARAARTCNGGNAARMGNGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TTYATHTTY AARAARTTYGTNCAYCCNCARYTNGCNMGNMGNGARAARGARATHGAYGARATGATHGCN CARGCNAGYAARCARGGNTAYAGYACNYTNYTNTCNYTNGGNTCNAARGGNGTNAAYTAY GCNTCNCARATGGTNATGMGNACNGCNATHATGGGNCARTCNAARYTNGTNGAYCAYYTN MGNMGNAGYTAYAGYACNAGYGAYYTNACNGAYGAYGGNCARTCNGTNATGCARMGNCAY GARGCNGTNGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MGNCCNAAR AGYCAYAGYAGYAARAAYMGNCCNTCNAGYTCNATGAGYTGGATHAARTCNCAYGARACN GTNAAYACNGGNMGNTCNGGNTTYYTNGCNAGYMGNCCNTCNAGYGCNGTNTCNTCNYTN GCNGARMGNGARCCNTGGGARGAYGAYACNTCNATHATHACNAARAARATHYTNAARTCN CARGCNMGNGCNCARATGGGNAARMGNAAYTCNGTNTAYCARCCNGCNGGNGCNGTNYTN AAYTCNCARTCNTCNAARAARGTNMGNGAYYTNGCNMGNAARATHMGNATHAAYTCNACN CARATHTCNTTYGAYAGYTTYGAYCCNTCNGTNTCNMGNCARGGNGTN---YTNGARGAY AARCCNCCNAARMGNCCNGCNACNGGNAARGAYYTNATGGGNMGNMGNGCNACNTCNGGN GARATHATGAAYCARCAYAARCCNACNYTNAGYGCNGGNGCNTGGAARCARCAYYTNGGN AARTCNAGYGCNTCNCCNATGTCNGCNTCNGCNCARCARMGNGGNATGYTNGARGCNAAR AARAAYYTNAAYGARACNMGNMGNGCNGAYGTNGCNGARAARGTNAARGAYTTYATG--- ------------------------------------------------------------ ---ATGTCNAGYTCNTCNATGCAYGGNGGNTAYGCNAAYGCNGCNATHTAYAGYCAYAAY MGNTCNCAYAGYYTNACNATHGAYAARGARTCNGAYGARCAYMGNCCNGCNTTYGTNAAY AGYYTNAAYTCNTCNAAYTTYAGYYTNGCNGAYYTNGAYGAYGCNATHGAYYTNAAYAAR ---AARCARATGTCNGCNGCNGAYATHGAYCARATGCARMGNGARATHCARTCNYTNMGN AARTCNYTNMGNAGYGCNAARCAYGAYMGNTGGGTNAARYTNCCNGTNCARGAYACNYTN MGNMGNATHATGMGNGGNGARTCNTAYTCNYTNGARATGTAYMGNTCNYTNGCNGAYAAR MGNGAYYTNGTNGAYTCNGCNGTNAARACNCAYGAYGGNAAYGCNATHACNGCNGCNGTN YTNTTYATGAARAARACNACNAGYGCNCARATHTTYACNMGNGARYTNAARCARMGNCCN GTNGCNGCNAAYCAYTAYYTNCARTAYYTNAARGARCAYTAYGAYTTYAAYGARTAYGTN GARACNYTNAGYATHYTNGGNMGNACNGARGARGCNGCNATHTTYAARTTYCARYTNGCN YTNCCNACNCCNGAYGTNACNYTNAARATHTCNAARYTNAARGAYTCNYTNMGNAGYCAY TTYAAYGCNGAYCCNACNYTNTCNTCNCAYTCNTCNYTNGTNCAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNYTNTTYAARACNAARGGNTCNTCNMGNAARMGNAAR CARATHYTNTCNGGNGGNAARMGNTGGMGNGCNTCNMGNGGNAAYMGNYTNTCNCAY--- ---CCNTCNGGNAARTCNGAYGAYGARGARGARGARGAYAAYCARGAYACNGCNATGGGN GAYGARATGAGYAGYTCNAAYAGYGCNCARGARACNAGYTCNTCNGCNGCNTCNCCNCAY TCNACNCCNGAYTTYAAYATGGARATGGARGGNAAYTAY---CCNAAYAARGAYCCNTCN AARTGGAGYGTNACNGARGTNTAYGARTTYGTNYTNTCNYTNCCNGGNTGYTCNGAYTAY GCNGAYGAYTTYMGNTCNCARGARATHGAYGGNCARGCNYTNYTNYTNYTNAARGARGAY CAYYTNATGACNGCNATGAAYATHAARYTNGGNCCNGCNYTNAARATHTGYGCNAARATH AAYTCNYTNMGNATHGARCCNCAYCCNTTYCAYACNAAYAGYTGYTGYCAYGTNAAYMGN MGNAARGARAAYGCNGTNGTNAARCAYYTNTAYTAYAARGAYCAYGARAARTCNYTNGAR CAYTCNCAYAGYCCNYTNGTNGARYTNCCNGAYTAYACNTAYCARGAYGGNMGNGCNACN GARACNACNATHTGYCAYAARGTNMGNCARGARAARAAYTAYAAYYTNGCNAARCARGTN GTNAARYTNGTNGARGARATGAARTTYGCNCARAGYCAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TGYCAYTCNATH GAYCCNMGNAARACNTGGAARCCNGARGARCCNAGYGGNTAYGTNYTNGGNGGNCAYTGG CARTCNTTYYTNTGYTCNGGNYTNAARTCNMGNGARTGYYTNAARAAYAARAAYATHATH ATHYTNGGNGAYTCNAAYGCNMGNAGYCAYTAYGAYCAYYTNGGNAARTTYGTNAARTGY CARCARYTNATGACNMGNACNACNAARATHTGGCAYAARCCNYTNAARTGYTTYAGYCCN ACNTTYAAYACNACNATHTCNTGGAAYCCNCAYTCNCARCCNTTYYTNTCNTAYTCNGAY MGNTGGACNAAYAAYGARGAYYTNATHCCNTCNGTNCAYGTNATHGAYCARGCNCCNAAY MGNCARTAYATHYTNCAYCAYTAYATHCAYYTNACNCCNTTYCAYATGAGYTCNTTYGAR GCNAARTAYMGNGCNATGAARGARGCNYTNTCNMGNYTNATHAARMGNATHCCNACNGTN MGNGTNGTNGTNCARGGNGCNCAYGTNGCNTGGGAYGGNTGGAARAARCAYACNGCNGGN GAYCARYTNGGNAARTTYATHACNCCNATHCARMGNGARGTNTTYMGNGAYYTNCARGAY AARGTNTTYTTYGCNCCNTTYTGGGAYATHTCNACNGCNATGGARTAYCAYTCNTTYCAY ATGTCNYTNGARYTNGTNTCNAARTGYYTNGARYTNGAR------GAYYTNAGYGTNAAR GGNGARAGYTCNGGNMGNAARAAYAARMGNTTYAARACNAAYAAYGCNATGGAYATHATH CCNACNAAYAARCAYGGNGTNTGGAARGARYTNMGNAARGTNMGNAARGGNCARYTNMGN GARATHAARAARAARMGNAARGCNGARATHTTYAARTCNGCNATHGARATGTAYAARGAY AARCAYGAYATHGAYCAYACNGAYMGNAAYGTNGARACNYTNYTNAARATHTCNAARYTN GGNMGNGTNGAYACNAARTGYGCNGARAARATHYTNTAYCAYCARCCNTGYMGNYTNTCN MGNGAYATHAARCCNGGNACNGARATGTCNAARCCNACNACNGTNTTYACNGARGAYGAY TTYGARGCNTTYGCNAARGARTAYCARCCNAAR---------ATGTCN------GTNCCN CAYACN------------CCN---CCNYTNGGNGGNGGNAAYCARCARGAYMGNCARAAY MGNAARYTNYTNYTNGARCAYATHCARGARCARAARAARMGNYTNCARCAYGGNCAYCAY TCNTCNTCNACNAGYACNCCNACNCCNTCNATGAGYTCNGGNCCNGCNACNATHATHGGN AAY---CCNTCNTCNATHCCNGGNYTNTCNGCNGCNGARTAYGCNACNATHAGYAAYCCN CARCARMGNGCNGCNYTNCARCAYGCNCAYGCNAAYTCNGTNGGNTTYTTYATHACNCAR GAYTCNTCNTTYGGNAAYYTNATHYTNCCNGTNYTNCCNMGNGCNCCNGAYACNAARACN GARGCNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CAYCCNYTNGGNCARYTNACNTAYCARACNTTYGTNGARGCNGAYTTYGTNAAY ATGGCNAARCARTAYAAYTAYGTNGCNGGNGTNGGNTTYGAYAARCCNAAYGTNACNGTN AAYGCNCAYCCNGARAARAARYTNTGGGARATGGGNGTNATHAGYTTYCAYMGNAARATH GAYTAYTCNTGYAAYTTYTGGYTNGARYTNAARACNYTNGAYATHCARACNGAYATHAAR TAYGGNGCNCCNATHAGYTTYTTYYTNAAYTAYGTNTCNGTNCCNAARAARGGNYTNAAY GTNACNGTNYTNGTNGCNAAYAARACNACNACNMGNYTNCCNGARTCNGTNTCNYTNAAY TTYACNCCNAARAAYGAYAAYCCNAGYTGGTTYATGACNAARATGAAYMGNGAYATHGAY CCNTGYACNGTNGTNYTNAAYGGNAGYCARTAYGTNCAYGCNGTNGAYTCNACNGTNAAR YTNACNGAYGARAGYAARAAYGGNYTNGTNATHTCNGCNCARGAYTCNCCNGTNATHYTN TGGGGNACNGCNYTNCAYACNCCNTCNCCNTTYCCNGTNCCNYTNCARCCNTTYAAYTGY TCNACNYTNACNTCNGTNGCNTTYAAYYTNTAYAAYAAYATHTGGAAYACNAAYTAYATH TAYTAYTAYCCNTAYAGYAAYTAYGAYGCNAGYTTYAARTCNMGNTTYAGYYTNTAYTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNTCNCCNMGNAARGCNTAYTCNACNACNAAY YTNTCNAGYATHAARAARAARACNTCNTTYMGNGARAAR---------------ACNAAR GGNGAYTCNACNCCNTCNACN---------ACNCCNMGNCAYACNCCNMGNMGNGAYCAY TCNGCNTCNTCNCCNMGNACNACNGGNGGNAGYAGYGTNTCNCCNGCNCCNGGNATHATG TCNAARTCNGCNTCNGCNTCNCCNMGNATHACNCCNCCNYTNTCNTCNTCNACNTCNTCN TCNCCNCAYCCNACNACNACNCCNAGYATHAGYATHACNTCNCAYGGNAAYGCNACNCCN ACNCCNAGYTCNGARGAYGGNACNGCNACNCCNMGNGGNGCNGGNGCNGCNCARGAYATH TCNAARGARGCNTAYAARGCNAARATGGCNGARMGNMGNMGNCARGCNMGNGARAARGCN GARAARGARGCNGARGARGARMGNMGNMGNCARGARGARGARMGNYTNGCNGARGARGAR ATHATGMGNCARGARGARGARGARCARYTNMGNYTNGARGARGARACNATHMGNYTNGCN GARGARGCNMGNAARGCNGARGARGARMGNYTNCARAARGCNATHGARGCNGARGARAAR MGNAARAARGARGARGCNGARMGNYTNGARCARGARMGNAARGCNAARGARGARGCNGAY MGNAARGCNAARGARGARGCNGARMGNATHGARAARGARAARCARGARMGNGCNAARAAR GARGARGARGARMGNYTNCARMGNAARAARAARYTNGARATGATHATGAARMGNGTNAAR ACNGAY------------------CCNGCNCARGAY------------------AARGTN GAYAGYCCNGTNAARTCNTCNGGNAGYTCNCCNAAYMGNAGYGCNYTNGCN--------- ---TCNCCNGARGTNCARGARATGCCNYTNTTYACNCARGARAAYGAYAAYTCNTCNGGN TCNGARGAYGGNAARCARAAYGAYGCN--------------------------------- ---------------------------CCNGCNCCNAGYGCNTCNGARAAYGCNGARAAY TCNGTNATHTCNTCNTCNTCNTCNTCNGARCCNGCNGCNYTNACN--------------- ------------CCNGTNGTNMGNAGYGCNTCNTCNGGNGAYATHATHGAYAGYGCN--- GCNGAYGARGAYAARAARGARATGGARAARGGNGAY---------AGYYTNGGNACNYTN AAYACNCCNGTNAARTCNTCNACNAGYMGNACNACNTCNGARCCNTCNTCNACNGARGTN AARTCNMGNTTYAARTCNCCNYTNYTNCARCARYTNGTNGARAAYAARGGNGGNTCNGAY TCNCCNAGYGGNTCNCCNAARTTYAARTCNCCNYTNYTNCARAAYYTNYTNGGNAARACN AARGTNGGNGCNMGNATGGGNYTNTCNGCNAGYATGGGNGAYYTNAAYYTNAAYAARGAY AAYAAYACNAAYGCNGCNAGYAGYACNACNCARCARCARCARCARAGYTCNAGYCCNCAR TCNYTNAGYCCNTCNGGNTCNAGYAARGARATHTCNAARGCNGGNCARGAYGARGAYAAR GAYGTNGAYGARTCNGTNGGNTCNTCNGCNTCNTCN------ACNTCNGGNAAYGAYCAR GARTCNTTYAARGCNCARTCNTCNCAYGAYGARGAYCAYYTNACNAAYGGNAARTCNTCN GARGAYGARTCNGGNGGNMGNAARTTYTCNCCNATHGGNATGATHGAYTCNGCNYTNGGN TCNAGYATHGARCCNCARCARGGNGAYGTNYTNGARTTYGCNGCNCCNAGYTCNGTNATG TCNAAYGGNCAYGGNGCNAARAAYAARCARGAYYTNATGGARGAYTCNAGYATHAGYGTN CARACNCCNGARGGNCARTCNTCNTCNCARGAYGARACNGARGARGARGAYGAYGAYGAY GAYGAYGAYGARGARMGNMGNGARGGNGGNAGYGGNCAYTTYGARGARYTNATHGAYYTN CCNTAYTCNACNAGYAGYTCNACNAARTCNGCNGTN------TCNCCNATHATHGCNTTY GARGARAAYAGYYTNMGNACNGCNGAYGTNGGNGARTCNATGTCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATHAAYTCNAAYGGNCARGTNYTNGARTCNCARTCNCCNTGGMGN YTNTCNTTYATHACNGAYGCNATHTGGGGNATHATHAAYTTYATHGTNYTNTTYTTYCAR ACNATGTAYAAYCCNAAYAARAAYAGYMGNGGNGAYAAYTAYACNACNGAYTAYMGNMGN CCNGGNGGNGGNGGNCCNCCNACNMGNMGNATGGGNGGNTTYMGNGGNGGNMGNGGNGGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTNATHTCNTCNYTNTAYCCN AAYACNGTNCAYTCNGARGGNGTNYTNAAYCARATHTAYGARAAYCARAAYAARAAYMGN ACNMGNCCNTGYGTNCARAGYMGNTCNGAYGTNTTYMGNATHYTNAARTAYGAYATHAAY ACNGCNGGNGARGGNTCNGAYCAYACNCARCCNYTNYTNYTNACNMGNCAYAAYATHGTN CCNGGNATGTTYYTNATHTAYGCNGAYGGNAARYTNYTNTTYTGYGAYCAYATHTTYAAY GGNTAYGGNAAYACNAARACNGAYTTYMGNAARCARGTNATGAARTCNMGNYTNGAYTAY ATHCAYGGNTTYTCNYTNCCNCARGAYTTYMGNTTYAGYCCNTCNMGNGGNYTNCAYGGN CCNMGNGCNCCNTGGGGNGGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TAYTTYACNYTNYTNCARGGNACNTGGTTYTGG CARATHTCNTTYATHYTNTGGAARCCNTTYGGNYTNCCNTGGAARCAYGAYGAYGARGGN GAYYTNACNYTNGCNTGYYTNTTYTTYGCNTGGCAYTGYGGNGGNAAYYTNYTNYTNGTN GTNTCNGGNATHGTNACNTTYYTNTAYMGNGGNAARGGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATHTCNAARATGGCNYTNATHACNTCNGAYYTNGARACNGARGTNATHAGYGAYAGYTCN GTNATHCCNCCNTCNTCNAARTCNTCNATHGTNAAYYTNMGNGTNAARCCNAARGARTCN GGNACNYTNAARGTNCARGGNTAYTCNACNGTNGTNTTYGGNGTNAARAGYAAYTGYMGN YTNMGNGAYYTNACNMGNYTNAARCCNTCNCCNYTNAAYGARATHTCNATHCARGTNATH CCNMGNYTNCCNCARGTNACNATGTCNTGYTCNYTNCCNAARTCNATGYTNAAYTCNAAY TCNGGNCAYGCNTCNCAYATGGTNGAYACNGGNTCNGTNGTNYTNTTYGCNGGNCARAGY GTNGARTGYGTNGTNYTNCARTCNGGNATGGCNATHYTNCCNTGYTCNGTNMGNAAYYTN GGNGARMGNCARGTNGTNTGGMGNMGNYTNAARAGYGAYGARTTYYTNACNATHGGNGCN ATGGTNTGGACNAARGAYCAYMGNGTNATHGTNGAYTTYGAYYTNGAYGAYGAYGGNACN ACNGCNTGGGAYYTNATHATHMGNAAYGTNCARTTYTCNGAYTCNGGNATHTAYGARTGY CARATH------------------------------------------------GAYATH ACNCARYTNTCNGTNGAYGTNATHGTNAAYTCNGCNACNMGNTCNYTNCARGTNAGYGGN GTNTCNAARGCNATHTCNTCNGCNGCNAARYTNCARAAYGARTGYAARAARCAYYTNAAR TCNAAYACNYTNGTNGAYGTNTCNCAYCAYTTYGCNTCNACNGGNGGNAAYYTNAARGCN AARCARGTNTAYCAYGCNGTNGGNCCNAARTGGGARTTYTAYAARGAYAAYCCNGARAAY TGYAARMGNGTNYTNMGNYTNACNATHATHMGNTGYYTNTTYCAYGCNGARGARCARGGN TAYAARACNATHGCNTTYCCNTCNATHAGYTCNGCNAAYTTYAARGTNCCNATGGARATH TGYGTNGAYAGYTAYATGAARGCNGTNYTNCAYTTYGARAARYTNMGNAAYACNGARTCN YTNAAYGTNGTNCAYTTYGTNGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY MGNATGGARAARACNTAYGGNATGGARACNTGYMGNTGYYTNTTYTCNGCNGCNAAYGTN TAYACNAARTCNAARYTNGCNAARAARGARCARGTNGARAARGCNGTNTCNAAYYTNAAR AAYYTNACNAARGTNTTYAARYTNACNGAYACNGAYGAYACNAAYTTYYTNGARAARTCN GARYTNMGNYTNYTNTTYAARATHYTNGARTAYCAYGTNAGYGAYGAYYTNYTNCAYAGY ATHATGACNMGNTAYGGNGGNMGNAARCARMGNYTNGGNYTNGARGAYTTYGTNCAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TAYCCNCARYTNCCNCARCCNGCNGARTTYTCNAARGGNGAYGARTTYMGN GARTTYYTNYTNACNAARYTNATHAAYGCNGARYTNGCNAGYTAYAARGCNGAYCARTTY GCNAARYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGAYCAYCAYTAYGGNGTNGCNGTN ACNAAYAARTTYGCNYTNTTYACNGAYGAYGAYGARGAYCCNATHGARGCNGTN------ ---------YTNAARATHAAYGCNCARAARGAYGARGAYAARAARGCNAARGCNAARAAR ACNYTNGARGARGARGAYMGNAARGCNGAYAARCCNGCNGCNCCNCARAAYGAYGAYGCN GARCARAAR---------GARGTNGGNGAYAARCARTGGCARACNGARAARGGNAARGGN AGYGCNMGNAAYMGNGARCCNMGNGARYTNMGNGARAAYGAYGGNGAYMGNMGNCCNCCN MGNMGNCARGGNCCNMGNGARTTYAARGAYGGNAARGCNCCNMGNGAYTAYAARGAYGGN AARCCNCCNMGNGAYTAYAARGAYGGNAARGCNGGNGAYGARAAYGTNCCNCCNGARTTY MGNGARCARCCNCARGGN---GGNTTYAARMGNMGNGARGAYMGN------GARGGNAGY GGNTTYGGNGGNGARMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNGGNMGNGGN GGNGARMGNAAYAGYGGNAGYGGNTTYGGNCCNMGN------------------GGNGAY CARAARMGNGARTTYGAYMGNCAYAGYGGNACNGAYMGNACNGGNATHAARGCNATHGAR AARAARGARGGNCAYGGNCCNCAYAAYTGGGGNAGYTTYMGNGAYGAYATHGARGARCAR GGNCARGCNGCN---------GCNCCNGARGAR---AGYAAYGARMGNGARAAYCARCCN GARAARACNGARYTNAAYGARAGYGTNGARGGNGGNAAYGTNGCNGARGARGAYGTNCAR CCNCARCARATGACNYTNGAYGARTGGAARGCNYTNCAR---GTNCARAGYAARCCNAAR CCNAARTTYAARATHMGNCARGCNGGNGARGGNGTNGAYTCNGGNCARTGGAARCARGGN GTNGARTAYCARAARAAR---YTNGTNGCNGAYCARGAYCAYGGNGARCAYGARAGYGAY CAYAGYGAYCAYCCNGGNMGNGAY---------AAYAARCARYTNYTNTCNGAYATHMGN ATHACNTTYAAYGAYAAYCCNMGNMGNGGNMGNGGNMGN---MGNGGNGGNMGNGGNGGN ATGGARMGNGGNGGNMGNGGNACNMGNGGNAGYMGN---------------------GGN GCNCCNMGNGGNTTYGGNAAYAAR---AARGARGCNGCNCCNMGNTTY---GAYGARGCN GAYTTYCCNTCNYTNYTNAARACNGCNGCN------------------------------ ---------------------------------------------------------CCN AARTCNACNAGYCAYAAYCCNACNCCNMGNACNGGNGTNCCNGTNGAYYTNGAYAAYGTN TGGAGYATHMGNAAYGTNTCNYTNGGNGGNGGNGCNACNTCNGTNMGNTCNGARCCNGTN TCNTTYAARCCNGAYGTNYTNACNAARACNACNCAYTCNTCNTTYTAYTCNMGNCAYGGN GGNATGAAY---GGNMGNACNGGNAGY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNCAYGTNMGNCAYAARGGNAGYMGNCARMGNATHMGNGAYGCNAARYTNAAY GTNGAYAARAAYAARAARTTY---ACNAARAARGARMGNAARAARTCNCARCCN---YTN AGYAGYAAYYTNATHGARAARTCNACNATHATHGCNGARAARCCNGTNGAYAAYGTNTGG GTNMGNAARTTYTAYCCNACNCCNMGNTTYTCNATHAAYACNGCNYTNGARMGNCAYCAR GCNTTYGCNCARCCNGCNATGYTNGAYAAYATGGAYGGNYTNGTNTAYYTNGAYATGTCN YTNGAYTAYGCNACNAARAARAARACNAARTTYATGAARAAYTTYMGNTCNACNYTNYTN YTNCCNCAYCCNTTYAAYTGGGGNAARCCNCCNTCNATHYTNGTNTTYTGYAARGARGAR GARCAYACNAAYYTNGCNATGTCNYTNGGNGCNMGNCAYGCNGGNGAYCCNGCNGARGTN ATHAARYTNATHGARAGYGGNGTNYTNCAYCCNAARGAYTTYAAYCAYGTNYTNGCNACN GTNGAYTGYACNAAYGARATGTCNCCNGCNMGNTCNTAYTTYMGNGAYAARTTYCCNCAR AARGCNAARGGNAAYYTNGGNACNGAYYTNAAYGCNATGTGGACNYTNTTYTAYAAYGGN TAYACNTAYGARACNCARAGYYTNTCNGARTTYCARGGNMGNYTNCARGTNCCNATHGGN CARYTNAARCARCCNACNAGYCAYATHATHGCNAAYTTYGARGCNTTYATHGAYTCNATH TGYAARCAYMGNAGYGTNGCNYTNGGNCCNTTYATHCARTCNATGACNGTNGTNGCNCCN CCNTCNCCNGARGARTTYATHGTNAARGTNGARGAYTAYGTNCCNGGNTAYAARAAYGAR GARGTNGAYTCNGAYGAYGARGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY GARTAYGAYGCNGAYACNGAYGTNGAYGARCCNAGYGARGTNAARAARGARGARMGNAAR CCNYTNTGYAARTAYGGNAGYAARTGYTAYMGNAARAGYACNTCNCAYYTNCARGARTTY TTYCAYCCNMGNAAYAARMGNAARACNGARGARCAYAAYGARACNGCNTCNCCNTCNAAR AARYTNAARAGYTAYCCNGARAARACNMGNCCNAAYGTNTTYGARGAYTTYGARCCNTTY GGNTTYTTYYTNACNAARGTNTCNGGNATHCCNCCNCARTTYAAYACNATHGGNGCNATG AGYYTNAARGAYATHYTNTCNCCNGARATGGGNCARYTNAARMGNTCNTGYCAYTTYAAY TTYATGTTYGAYGTNCCNTGGYTNGTNCARCARTAYTCNCAYACNGAYMGNTCNYTNCCN ATHATGYTNGTNCAYGGNGAYCARGGNMGNGCNGARYTNGAYYTNAARCAYGARGCNTCN CCNTAYCCNAAYATHTCNYTNTGYMGNGCNMGNYTNGAYATHCCNTAYGGNACNCAYCAY ACNAARATGATGTTYYTNYTNTAYGARACNGGNYTNMGNGTNATHGTNCAYACNGCNAAY YTNATHCCNAAYGAYTGGCAYCARAARACNCARGGNATHTGGATHAGYCCNACNTTYCCN MGNYTNAARAAYCCN---TCNGAYCCNGGNGARTCNMGNACNAARTTYAARGCNAAYYTN YTNCARTAYGTNTCNGCNTAYAARTCNCCNMGNYTNTCNCCNTGGGARACNATHATHTCN GAYCAYGAYYTNTCNTCNGCNACNGTNCAYATHGTNGCNTCNGTNCCNGGNMGNCAYACN ATGAAYGAYAARCAYCAYTGGGGNCAYYTNAARYTNAARAARATHYTNTCNGCNGGNGGN CCNGAYCARGGNYTNGTNAARAAYTGGCCNGTNATHGGNCARTTYTCNAGYATHGGNTCN YTNGGNGCNAAYCARGAYGCNTGGYTNYTNAGYGARTGGGGNCARTCNYTNTGGACNTGY GTNAARTCNYTNCCNTCNCCNATHCCNCCNTCNAARYTNCAYYTNATHTTYCCNTCNAAR GAYAAYATHMGNYTNAGYYTNGARGGNTAYAAYGGNGGNGGNTGYGTNCCNTAYTCNATH AARACNGCNTCNAARCARCCNTGGYTNACNCCNTTYTTYTGYCARTGGAARTCNGARGGN MGNGGNMGNTCNMGNGCNGTNCCNCAYATHAARACNTAYACNMGNTCNTCNCCNGAYGGN TCNGARACNGCNTGGTTYYTNGTNACNAGYGCNAAYYTNTCNAARGCNGCNTGGGGNGCN TTYGARAARAARGGNAGYCARYTNATGATHMGNTCNTAYGARATGGGNGTNYTNTTYYTN CCNGGNGAYTTYGGNTGYAARAAYTCNTTYAARGTNACNAGYCARATHGAYAARYTNCCN AAYCCNGARGTNAARACNTTYCCNYTNCCNTAYGAYYTNCCNACNACNACNTAYATHAAR GGN---AARAARTCNGTNGARYTNTTYTAYGAYGTNGTNTCNCCNTAYTCNTGGTTYGGN TTYGARGTNATGATGMGNTAYCARAAYMGNTGGAAYATHAAYYTNAARYTNMGNCCNTTY TTYYTNGGNGGNGTNATGCARTCNTCNGGNAAYAARCCNCCNGGNYTNGTNCCNAAYAAR GGNATGTAYAGYATGYTNGAYGTNGARMGNTGYGCNMGNTAYTAYGAYGTNCCNYTNGTN ATHCCNAARAAYCCNGGNGARYTNATGTTYGARAARGGNTCNYTNAARGCNCARMGNTTY YTNACNGCNGTNGAYATGAARTGYCCNGAYAARGTNGARGCNGTNTCNMGNGARTTYTGG ATGMGNGGNTGGTGYMGNGAYGARGAYYTNTCNGARGAYGCNAGYYTNGCNGARGCNGCN CARAARGCNGGNYTNAGYCARCARGAYATHCARGAYTTYYTNTCNMGNGTNAARGAYCAR GAYGTNAARGAYMGNYTNAARAARACNACNGAYGARGCNATGGAYYTNGGNGCNTTYGGN TCNCCNATGATHGTNGCNGARGTNAAYGGNAARAARGARTGGGTNTTYGGNAGYGAYMGN TTYCCNATHYTNGCNCARATHYTNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CCNGCNAGYCCNTAYAAYCCNTAYATHACNACNTCNGTNCCNTCNCAYACNGTNGCNATG ACNACNAAYGGNGAYGCNAAYTCNCCNATHATHTCNCARGCNYTNACNCAYACNATGATH CCNGCNACNCCNAARGCNGTNMGNGCNGAYAARTTYGARACNATHCARGARAAYGGNGAR GGNYTNACNAGYCAYACNCAYYTNGTNGAYCCNYTNACNTTYCCNACNTAYTTYACNCAR CARAGYTCNGTNCCNGGNATHATHCCNGCNTAYAARMGNATHGCNATGGGNGAY---GCN TCNGTNGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TAYAAR YTNAARMGNCARAAYMGNAGYAARACNYTNCCNATGGGNAGYGCNGARGARGAYAAYGCN AGY---AARATHCARMGNGCNGCNTCNCAYMGN---GCNCCNGCNACNAAYTCNCCNCCN GARGARACNCCNGCNAGY---------------TCNTCNAGYGTNAARAARYTNGGNGCN ACNMGNTTYAGYCARTTYGARTCNAGYGCNTCNTCNGARCCNTCNTGG------ATGAAY MGNGCNAARCARAARAARTCNGAYAGYGARGARCAYGAYYTNAARAAYCARTCNGARGAY AGYATHMGNMGNCARAGYTAYGARAAYGTNYTNGCNCCNGCNTCNAARTCNTCNGARTCN ACNTCNCARACNAARCAYGTNCCNTCNTCNTCNAGYTCNAARGARATGAARACNGAYGTN ACNGAYACNAAYTCNAAYMGNAGYGCNGARTCNGARAARGAYAARAARGCNGAYAAYAAY TCNAAYAGYAARMGNCCNAGYATHGAYATHTCNAGYACNAARMGNGARAGYATHGAYATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYGAYAGYYTNAAYGAYYTNGARGAY TGGTGGGCNYTNCARAARMGNAAYMGNYTNACNTCNGTNTTYCARGAYGTNYTNGTNGAY AARGCNYTNYTNAARTTYACNAAYTGYGCNAARYTNACNYTNMGNGTNAARYTNTGGGAR GAYGARATHAARGGNTGYMGNGARGAYYTNMGNAARMGNCCNGARACNMGNGTNAARYTN GCNAGYTCNGARMGNGAYTTYGCNYTNGTNAARMGNATHCARGARCAYCARAARGTNATG CCNGARAARGTNGCNMGNGCNMGNGAYGCNGARAGYCARTTYGARCAYAARYTNGGNGAR TTYATGYTNACNATHAARCARATHYTNCCNCARAAYACNCARATHATHAARTCNATHAAR GARTTYCAYACNAAYYTNAARATGGCNMGNGGNGTNAARAARGTNAAYTAYGAYAAYATH GAYCAYTAYYTNCAYTCNYTNGARTTYTTYMGNAARACNTTYCARGARATHGARAARGAR ATHGTNCAYCCNYTNTGYCARATHCARGGNGTNTGYGARAAYGARAARCARMGNAAYYTN AARAARACNGTNAARAARGCNACNTCNGARATGYTNGGNTAYYTNAARCCNGAYGTNGAY YTNCARAARGTNMGNCAYAARGARTGGGARGGNAARGTNYTNACNMGNGARCARGGNYTN TTYTAYGGNYTNATHAGYYTNATHCCNATGAGYGTNGAYMGNYTNACNACNATHGAYTAY AGYGTNGAYGARTAYGTNAAYGAYTTYCCNGARATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CCNGTNGTNAARAARYTNAAYATHCCNAARCARYTNGGNTGYAARYTNAGYACN GARAGYYTNTCNYTNATHAARTCNAAYGARAARATHGAYMGNAAYGGNMGNACNTGGGAR GARGGNGARGTNCARTCNTCNAAYAGYGAYGAYTCNGAYAAR---GAYAGYGAYTCNGAY GAYAAYGAYGGNTAYCCNTCNGAYACNGGNTCNATHAAYTCNGAYAARGAYACNTGGAAR AGYTCNTCNTCNAARCAYAARAARAARCAYAARCAYAARCAYAARAARAARAARAARAAR AARTCNGGNAARGARAARGAYAARTCNAAYGGNAGYGCNGAYGARACNGGNAGYAARAAR TCNAARGARAARGGN--------------------------------------------- ------YTNGARAARMGNAGYAARAARGAYAARGARGARTCNAGYACNGAYGTNTGYCAY AARGAYAARAAYGAYGTNGAYAARGARACNAARTCNGAYGARAARGTNAARGARAAYGGN GAYAARTCNAARTGGAARACNAGYGAYTCNGARAGYTCNAARAARGAYAARAAYGTNTCN GAYAARGAYAARACNGAYAAYMGNAARAARGARAARAARAARMGNAARCAYGAYMGNTCN MGNTCNMGNACNCCNAARMGNTCNAARMGNTCNMGNTCNMGNTCNMGNTCNCCNMGNAAR TCNMGNMGNAGYACNAGYCCNAARMGNAGYMGNTAYAGYGARTGGGAYGCNMGNMGNTAY AGYGAYGAYCCNAARGTNAARMGNGAYMGNTCNGCNGAYMGNAARCARGAYMGNTCNAAR GARMGN---GAYAARGAYMGNGAYYTNMGNYTNCARATHGAYAARGCNAARYTNMGNAAR ATHGCNATHGCNAAYGCNYTNAAYTCNATGAARTCNGGNCARCCNGTNCCNGTNCARYTN GAYGTNGCNGCNGTNAARTCNGGNGGNAARTCNGTNGARGARYTNACNGAYTTYTGYAAR MGNATHTCNGARAARGARCARGARCARGTNGARAAYGCNATHAGYGAYAGYAGYGARGAR GAR---CCNGCNGTNCAYAGYGAYGAYCCNYTNATHCAYCAYCCNTTYAARGTNAARGAY ACNTCNACNAAYATHGTNATGAAYATHMGNAAYGCNAARCARYTNCCNGTNYTNACNCCN TCNGARAARCARGCNCARCARGCNTCNYTNMGNYTNGCNTTYCCNGTNTCNAGYGGNACN CAYCAYMGNGCNAGYGARTCNGARTGGGTNCCNGTNGARAARACNACNGCNCCNGTNACN ACNACNACNAGYAARCCNGTNGAYTCNAARAGYGCNACNGARTCNCARCCN--------- GARCCNAARAGY------AGYATHTTYCCNACNGCNCCNTCNACNGTNGAYATHGGNGCN ATHATHTCNGARMGNYTNCARGCNGTNMGNAARYTNCARGCNAAYCCNTAYGAYGTNCAR GCNYTNAGYTCNATGCAYAARGCNCARGARAARGCNAGYCARTGGGCNCARTCNAARCAY YTNCCNGGNCARTTYGTNGGNAGYACNGGNGCNCARGTNATGTCNCARCARGARYTNATG GGNGAYAARMGNMGNCARGCNTGGGTNAARAARTCNCARTTYAGYACNGCNACNCCNGTN AGYGGNGGNATHGGNATGTTYYTNYTNCARAARATGGGNTGGAARCARGGNGARGGNYTN GGNAARAAYAAYGARGGNAAYACNCARCCNYTNCARYTNGAYATHAARATHGAYMGNAAR GGNYTNCARAGYGCNGCNGAYAAYCCNAARTCNMGNCCNCARATHGCNCAYGTNCCNCAR GCNAARGAYYTNTCNCAY------------------AARCAYCCNGTNTCNGCNYTNATG GARYTNTGYAAYAARMGNMGNTGGGGNCCNCCNAAYTTYACNGTNGTNCARGARGAYGGN CCNGCNCAYAARAARTGYTTYYTNTTYAARGTNATHTCNATHGAYGTNAARGCNGGNGAY ACNGCNGTNYTNCCNTGYACNGTNMGNAAYAARGGNGAYTTYAARGTNGTNTGGCAYTCN TCNACNCAYMGNGTNYTNACNTTYGARAGYMGNMGNGTNTCNGGNGAYCCNMGNATHAGY GTNGARMGNCCNAAYGTNCAYGAYTGGAAYYTNCAYATHMGNGAYGTNTCNGTNMGNGAY GARGGNGCNTAYAGYTGYTCNATHAAYACNTCNCCNYTNACNAGYCARGTNGTNCARYTN AAYGTNGTNCAYATGYTNAAYTCNACNATHACNACNMGNCCNGCNYTNGCNGTNTGGAAY YTNCAYATHMGNGAYGTNCARGCNMGNGAYGARGGNGAYTAYAARTGYATGACNAAYACN GCNACNCCNCARGTNATHMGNYTNMGNGTNMGNCCNGGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARATHGAY MGNGARYTNCCNCAYYTNATGAARGGNCARGTNCAYMGNYTNGTNGGNACNATGGGNAAR AARCARGGNGTNTTYAARGTNGTNTCNATHMGNAARGCNGAYAARGARGARMGNYTNTCN TGYCARCARGCNACNGARGTNTCNYTNAAYGARATGGAYAARYTNGCNMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARAARTTYCCNMGNCCNGTN CAYACNTTYATHTTYAAYGTNCAYGTNGCNTGGTCNGAYACNGAYAGYAAYGCNCAYTGY AAYTTYTCNTCNTAYCCNAARTTYGCNGAYGAYGCNYTNMGNGCNGCNYTNMGNATHMGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNAARCARTTYCCNAARGTNGCNGAYGCNCCNGAYYTNATGAARYTN TTYMGNACNTCNTGGYTNGARAARYTNAARGAYGTNMGNAARGCNGARAARMGNGAYGAR GARTAYATGAARGARYTNTTYMGNCARGTNTTYATGGAYTCNATHTTYCCNGTNCAYCAY GTNGCNACNYTNCCNGCNTAYMGNATGGGNGAYGARGAYAAYGAYAARATHMGNCARGAR AAYYTNGTNMGNTAYAAYGARATHAARMGNGGNAAYAARAGYGCNYTNGCNACNYTNYTN TCNCCNGAYYTNGTNTTYGAYCCNYTNTTYGTNGAYGARGTNGCNTAYAGYGTNATHGGN CCNAAYTGYYTNAGYAAR------------YTNGTNGTNCARGCNGARGARYTNGGNTGY GARGGNAARGTNGARGARGCNCARGGNGTNATGAARYTNGTNGAYCARYTNAARGARGAR MGNCAYCARYTNGARATGAARCCN---GCNATGCARGAYGAYGGNGGNCCNYTNATGAAR CARATGGARGTNTGYGAYGTNTGYGGNGCNTTYYTNATHGTNGGNGAYGCNCCNCARMGN CARGAYGARCAYYTNATGGGNAARCARCAYGCNGGNTAYGCNCARGTNMGNGCNGARATH GAYMGNMGNAARAARAARGTNMGNGAYGARACNGARGCNMGNGARGCNAAYGARAAYMGN YTNMGNYTNGARMGNGARGARMGNGARAARGARMGNCARMGNGARMGNGARGARMGNMGN ---MGNGARMGNGAYGTNGAYMGNMGNMGNGAYMGNGAYMGNGAYMGNMGNMGNAARAGY MGNTCNMGNAGYMGNGAYMGNGGNAARGAYMGNMGNMGNTCNMGNAGYMGNGAYMGNMGN MGNCARMGNAGYTCNAGYMGNGAYMGNMGNAAYAARMGNAGYMGNAGYCARAAYMGNGAR ------------------AGYTCNAGYMGNGGNAARMGNTCNMGNMGNTCNTCNAGYMGN GARMGNAARMGNGAYMGNGGNCAYTCNMGNGAYAARAARTCN------------MGNAGY MGNTCNMGNGAYMGNAARGAYMGNAGYMGN---GAYAARGAYYTNGARMGNAAYGGNGGN AGYACNAGYAGYMGNGARGARATHAGYMGNAARACNGGNGGNTAYGGN---AGYATHACN GAYGAYACNMGNYTNATHGAYTGYCCNAARMGNYTNATHGARTTYATHTCNGAYCAYTTY AAYGGNAGYAAYGCNTCNAAYTGGCARGAYYTNYTNGAYYTNTAYAARTGGTCNTAYAAY GARATHATGYTNTTYGGNAAYAARAGYCAYCCNCARGGNTAYTTYTGYAGYATHYTNAAR GARAGYCARTTYCARGAYTAYACNATHAARTAYYTNAARGARGAYYTNTAYAAYYTNCCN AARMGNGAYTCNYTNGCNGAYATHGARAARTGGATHGAYGAYCAYAAYATGGAYTTYGAY TCNTCNTCNAARTTYATHGCNTCNYTNGCNMGNTTYYTNCARTCNYTNTGYAAYGGNTAY GTNGARTTYGAYAARGGNGTNGARGTNATHGGNCAYATHTAYYTNAGYGTNGAYAGYGAY ACNGGNMGNAARATHGAYTAYGTNYTNAAYGARAARGTNTGYAARAAYGAYAAYTCNGTN ACNTTYATHAGYAAYAGYTTYCAYGCNCARCCNGCNGARAARCCNCARCCNGCNCCNAAR AARCCNGARGTNGAYAAYAARAAYGAYGAYTCNCAR------GAYGAYAGYGGNCARTCN ATHCCNAAYAGYACNAAYGTNGGNACNATGGGNGCNYTNMGNGAYGGNTCN--------- ------------------AAYAARMGNCCNMGNTCNCCNYTNCARMGNMGNATGGGNATG GGNMGNGGNTCNGGNGGNCCNGCNGCNAARTCNCCNMGNTAYCARGAYCARTCNGGNGCN TCNGCNAARTCNTAYAAYACNGAYGGNYTNTCNACNAAYAAY---AGYAGYGGNGARCAY TAYGAYAGYTCNTAY---------CARGGNGGNGAYGARGAYAAYTAYAGYCARGAYTAY ------------------TCNAAYTCNGAYYTNGAYCARAARCCNGTNATHGARCCNGAY ATHAGYATHGTNAARGARGARTAYATGGCNAAYCARCARCCNGGNGCNTCNTAY---CCN AAYATHCARCCNTCNGGNCCNGGNMGNGGNMGNCARCCNACNTCNTCNCARCARCCNTCN TAYCCNATGCAYCARAAYTCNTCNAAYTTYTCNTCN---------------------AGY AGYGAYTAYTCNGGNTCNTCNATHGARCCNMGNGAYCCNTCNGARYTNACNMGNGCNCAR CARGARGARYTNGARATGTAYTAYMGNAARGGNACNGAYCARCAYYTNACNTTYYTNMGN AAYATGMGNGARGCNCAYGCNATGTAYCCNTTYACNGGNAARMGNGAYAARGARYTNTTY GAYAARGCNYTNGCNGARYTNTGYGCNMGNATHCCNATHYTNAARGGNGAYGTNATHMGN GTNTCNATHCAYTTYYTNCAYATHTGYMGNTCNCARTGYCARTTYAARTCNCCNGGNCAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CCNTCNYTNTCNAGYAARCCNYTNACNCAYGTNACNAAR GGNMGNCCNMGNCCNCCNMGNTCNGTNMGNCCNACNMGNCCNATHYTNGAYACNGGNTCN ACNGARYTNGAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNATHATHGCNGGNCCNGAYACNGCNAAYAAR ACNTCNTTYGTNTTYCARGCNTCNGTNACNGCNGCNACNAAYGGNTTYAARGTNGTNCAY ATHTGYACNCAYCCNYTNTCNAARYTNCCNGCNYTNGTNCAYGGNATGCCNACNCCNGAR CCNTCNGTNATGAARAAYGTNGAYTTYYTNTAYTTYGARGARGCNACNGAYGTNATHGCN TAYTTYGCNAGYATHCAYATGAARAARAAYYTNCCNAGYTAYATHATHGTNGARGAYATH YTNTCNTAYGCNTCNCARAARCARGAYAARTCNGTNGARMGNACNATGGCNAARYTNYTN GCNYTNATHTCNAAYGCNAGYGCNTGGACNGCNAARAAYAAYGAYACNGGNAARTGYAGY GTNYTNYTNACNGCNCCNTCNMGNATHAARTCNATGCARAAYATHYTNMGNCARTTYGAY TAYGARGTNGCNATHTAYGARGGNCCNACNAARGAYGCNATGCARTCNAARYTNTCNTTY ACNGGNAAYAARGCNCAYGTNTCNYTNACNTTYCAYMGNCARAAYAARTGYYTNATHYTN GAYGAYGTNTGYGTNACNGTNAARGARAAYGTNAAYAARGARYTNATHCARATHAARACN GCNGAYGARCARGARATGCARMGNMGNATHGAYTCNTTYATHGGNAAYAARMGNAAYGAR GTNAAYGARMGNAAYATHMGNGARTTYATHTCNCCNTTYGGNTCNGAYCCNAAYAGYAGY TGYGCNMGNGTNGARGCNATHTAYGTNCAYMGNGARGGNATGAARAGYCAYATHAAYYTN AARAAYGTNGARAAYTCNTAYGGNCCNCARACNMGNYTNMGNCARGAYGAYCARGAYMGN MGNYTNTCNTGGATGATGCCNGCNGAYGCNCARMGNGCNGARGCNGTNGAYGARMGNYTN TCNAAYATGGARCAYCAYYTNAAYATHTCNGGNGAYGARGGNGAYATHTTYMGNMGNATH AARGCNYTNGARGARMGNATHAGYTTYYTNGARGGNYTNTCNCCNGARTAYTTYACNAAY GGNATHCCNCCNAGYAARMGNMGNAARACNAARCAYACNGARMGNGAR------------ GTNCCNACNAARCARACNGTNGCNGARATHTCNGGNCAYCCNACNGAYATHGTNGTNAAY AARTTYGARGAYCAYYTNTTYATHATHGTNACNCARTTYCARAARYTNGGNACNGTNATH GARGTNTCNMGNGAYGTNGTNAGYGAYGARGTNCARGGNCAYATHCCNATGTTYTCNACN AAYGTNYTNYTNGGNAARGAYGARCCNYTNACNCAYGTNATGGCNAARACNATHGTNACN GCNYTNAAYCCNCCNATHCCNGTNATHYTNACNYTNGCNYTNAARGARACNTCNCAYGCN TCNGTNCARGCNATHATHGARYTNATHAARTCNTGYYTNATGGCNACNAAYATHCAYTTY GARGCNMGNMGNMGNCARATGGTNYTNGAYMGNGCNTGYMGNGCNMGNAARGARATGTCN YTNGCNCARYTNTCNGAYMGNGCNGCNCCNGTNGARGAYGGNCCNAAR------CCNGAR ACNATHGTNTGYACNGAYCARGGNCARTTYTAYCARACNMGN---AGYGTNCAYGTNTGG ACNGGNCCNGARMGNAAYMGNMGNACNTAYGAYMGNAGYMGNGARGGNCCNATHYTNGGN AGYTCNTGGMGNCARYTNGARMGNGARATGAAYTTYMGNCARAARAGYYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGCCNAAR TTYTAYGARGAYATHGARGARCARCCNACNMGNMGNAARYTNGCNTGYGARGGNATHMGN GAYGAYYTNYTNGAYTGYYTNYTNAARAGYGAYTGYTGYAARATHGARAARAARACNCCN MGNGARTGYATG---------AGYMGNGTNGGNGAYCCNTCNGTNCCNAAYGARTGYCAY AARYTNMGNGTNGCNTTYTTYGAYTGYMGNMGNTCNATGYTNGAYATGMGNACNMGNTTY MGNGGNMGNAARGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARGGNYTNTCNACNGGNCAR GARGCNGCNGTNGGNATHYTNGTNATGGTNTGYATHGTNGGNGTNGCNATHGGNATGTTY GTNTGYTAYMGNMGNACNAAYATGACNAGYMGNAGYTTYAARGCNTTYYTNACNGGNGGN GTNMGNTAYAARACNTAYACNAAYGCN--------------------------------- ------MGNTCNMGNAARAAYGCNATHCARGCNAARATGAAYMGNGARAARAARAARGCN TAYATHAARAGYYTNGARCARGARATHTCNTCNYTNMGNGCNGAYAAYACNAARYTNAAR TCNGARAAYAARMGNATGCARAGYAAYATGTCNGAYYTNGARGARGARGTNGARTAYYTN AARTCNGTNYTNGTNAAYTCNAGYTCNYTNTCNGGNYTNYTNAARAAYATHTCNAAYGTN AARGARGTNAARYTNTCNGCNACNGTNYTNGGNMGNAARMGNYTNGTNACN------GAR GAYCAYAGYTAYAAYTTYGTNGCNTCNGTNCCNGARAARMGNGCNMGNMGNATHAAYGAR AAYYTNAARAARGCNGGNGTNTGYYTNCAYGTNAAYGGNGGNTCNGCNTGYYTNGARTTY TGYGCNCAYTGYTCNAARYTNGCNCAYAARACNYTNYTNAAYCCNGAYTTYGCNGGNYTN CCNGAYGAYTTYCAYMGNYTNGAYTGGAARCCNGAYGGNTCNCCNYTNTGYATHATGCAR YTNYTNTGYGARACNCAYGAYGGNYTNGTNGTNGARGCNAARACNATHAARGARCAYTGG TGGAARCCNCAYATHAARMGNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CARACNGTNYTNGCNAARACNTGYTGYGAYGGN ATHMGNTCNCCNGARAAYYTNTCNCARTCNYTNTCNCARGTNTTYAARMGNGAYTTYYTN GARTCNGARTTYYTNTCNGCNAARCCNGARAARTAYGGNGGNGTNYTNGCNYTNAARTAY GARGARACNTCNGAYGGNAARGARGTNGARYTNGGNTGGATHCAYTCNACNAAYAGYTTY TGYTTYGCNTTYATHGGNGGNGAYCARAARACNCCNAARGCNYTNATGTCNTCNYTNGAR CARGARTGYACNCCNGGNAARTCNTTYACNATGGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNMGNATHTTYYTNAGYGTNGCNACNGGNGTNYTNTTY GGNATHGCNYTNGARAARGGNMGNGTNTTYGARCCNCARGTNATHMGNGAYCARATGYTN TTYMGNMGNTTYGGNATGYTNAARATGTTYYTNTCNGCNTCNGCNGTNGGNATHYTNTGY TTYTCNTTYYTNCAYGGNATGCCNCAYACNATGMGNAARATGGGNYTNGCNYTNCARAAR TTYCCNGARAARCCNCCNGCNAARTCNYTNYTNGGNGTNGTNYTNGGNTCNGTNATHYTN GGNAGYGGNATGACNATHGCNGGNGCNTGYCCNGGNACNGTNYTNGTNCARYTNGCNACN GGNGTNGARAAYGCNTGGATHACNYTNGCNGGNGGNYTNTTYGGNACNATHGTNTAYGCN ACNTCNCARGCNGAYYTNCCNTTY------TTYTCNAARTCNAGYTCNCARCCNAARTAY YTNGAYAARTAYYTNAAYGTNCCNTAYTCNTCNATHGCNGTNCCNYTNTCNTGYGTNYTN GCNGGNGTNGTNTTYGCNYTNGARTCNTAYTCNCCNTGGTAYGARGARGTNGAYCCNTCN YTNYTNACNGARGGNYTNATGMGNGCNGGNGCNTGGCCNCCNTTYATHGCNGGNYTNATH ATHGGNACNYTNCARATHCCNACNATHYTNGCNAAYGARGAYACNYTNGGNTCNTCNAAY GCNTAYGCNACNATHATGTCN---------ACNATHTGGCCNTCNATHAAYTTYAAYAAY GARGARAGYTAYYTNAARMGNTTYMGNTAYGGNYTNGAYTAYTGGTGGCARGTNATHCAY GTNATGGCNGCNGTNTTYGGNGGNGCNYTNTCNGCNACNGCNTCNGGNACNATGGGNACN GTNCCNGGNYTNCCNTGGTAYCAYGCNTTYTCNGGNGGNTTYYTNATGYTNTAYGGNGCN MGNYTNGCNGGNGGNTGYACNAGYGGNCAYGGNYTNTCNGGNTTYGGNYTNYTNTCNYTN ATGTCNTTYGCNGCNGTNCCNGCNATGTTYGGNGGNGGNATHGCNACNGCNTTYTTYATG AARCAYGTNYTNAAYATHGARATG------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AAYYTNYTNAARTAYCARTCNGARYTNGARGARGCNYTNAARAAYGCN GCNGARGAYGCNCARTCNCARATHACNCAYYTNTCNAAYAARGTNYTNGARCAYGARAAR ACNGTNGTNGARYTNMGNCARCARATGACNTCNACNCAYYTNCARYTNGARGAYCARTGY AARACNYTNTCNGAYAAYMGNGARGCNATHMGNTCNGARYTNGTNAARYTNGARGARGAR AAYGAYAGYYTNGTNGAYAARTAYTCNAARACNGCNCARCARYTNCARAAYGARGAYATH AAYYTNCCNAAYAAYYTNGARGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNGARTAYMGNGGNMGNGGN---MGNAGY AGYAGYTGGMGNGGNGGNCCNCCNMGNGGNGGNGGNTTYMGNGGNGGNMGNGGNGGNGGN GGNGGNGAYMGNGARGGNGGNGGNMGNGGNAGYTTYMGNGGNMGNGGNGGNTTYTCNMGN GGNMGNGGNGGNCCNCCNMGNAGYMGNGAYGAYYTNTCNCCNCCNMGN------ATGTCN MGNAGYTAYGAYACNACNGAYMGNGGNMGNGGNCCNCCNCCNAGYMGNMGNCCNGAYMGN TAYGAYGAYAGYTTYGAYMGNGGN---CCNTCNATGMGNATGAARGAYATGTAYTCNTCN CCNCCNMGNGAYTCNAGYMGNAGYTTYGAYMGNCAYTCNCCNCCN------CCNMGNMGN GAYMGNGAYTAYCCNCCN---MGNCAYAGYGAYCAYGTNAGYTCNMGN---GAYTAYATH CCNCCNMGNAGYTAYAGYCCNCCNMGNGARTCNGGNTAY---AGYTCNTAYAARGAYTCN TAYAGYTCNGGNCCNMGNGARGAYMGNMGNCCNATGMGNGAYTAYGCNCCNCCNMGNGGN ACNGGNGAYTAYGAYMGNGGNGGN---AGYAGYMGNGAYTTYMGNGGNGGNCCNMGNGGN GAYTAY------AGYTCNMGNGAYTAYCCNCCNCCNTCN---MGNAAYGGNGARTTYMGN GAYTCNATGAGYAGYMGNGAYTTYMGNGAYGCNCCN---------MGNGGNGGNGAYMGN TAYGGNAGYGGNGGNMGNGGNGGNAGYAGYMGN--------------------------- ---------------GGNMGNTCNMGNTTY------------GAYGAYAGYMGNGGNCCN CCNCCNMGNGARTAYAGYTCNMGNGGN---------------MGNGGNGAYMGNGAYGAY GAYMGNGGNAGYMGN------GGNTTYATHAAYGGNGGNTCNMGNGGNTCNMGNGGNGCN CCNMGNGGNMGNGGNMGNGAYTTYTCNGGNAGYMGNGGNGAYMGNMGNTCNCCNAGYMGN GARGGNGCNGGNGGNAARMGNCCNMGNYTNGAYACNGGNGAYTAYMGNMGN------TCN ATHYTNGARACNAGYATHGGNAARGAYGCNGAYTGYGARMGNGTNTTYAARMGNTTYACN TAYAARTGYYTNCARATHATHGTNCARTCNMGNATHGARMGNCCNGTNYTNCARGGNAAR GAYACNTCNAAYGAYTAYTTYAGYATHAAYYTNCCNGAYAGYGGNTCNATHGAYGAYCAR ATHAARTAYACNYTNGARGGNATHAARTCNTTYCCNGTNAARGAYMGNTCNATHTGYGTN GARATHGCNYTNMGNACNAAYGAYGGNGAYCAYATGTTYYTNGARACNTGGGAYATHAGY TTYAAYYTNAGYAGYYTNGAYATGTCNGCNAGYAARGTNCARCAYATHTTYACNMGNATG GGNYTNACNYTNAARTCNYTNYTNTCNGCNACNMGNGCNACNCCNGCNTTYMGNYTNGCN AARAAYCARGGNGARAARGGNGGNGGNTAYAARYTNAAYTAYMGNTTYTAYYTNGGNCCN CCNAARACNCAYATGYTNGGNGARGAYTTYAARACNATGMGNGCNGGNGCNGTNCCNTCN GCNTTYGGNYTNYTNAGYGTNGGNGTNTCNTAYMGNACNAARYTNYTNYTNTCNCCNGAY ACNACNGCNTCNTCNTCNAGYGTNATGCARGTNACNGAYAAYTAYTTYATGAARGARAAY MGNGCNCAYTCNACNGGNCARGTNTAYTCNGAYCCNAARCCNTGYTAYTCNTCNGTNAAR MGNAARCCNTCNYTNTCN------------------AGYCCNGAYAAYATGGCNGCNACN CCNTAYAAYTAYACNATHTCNCCNTCNTCNCARGGNACNGAYGARGAY---GTNGCNTCN AARYTNTCNGCNGGNAAYAAYGCNATHCCNTGGCCNYTNGCNAGYATHYTNAAYATHGAY GARYTNCCNGARCCNGCNGTNGGNGCNTTYTCNGTNCARMGNCCNAAYGCNYTNAARGTN GARGARAAYGAYYTNCCNTTYGARGGNYTNATGAARMGNAGYATGATGGCNMGNYTNGAR CARAAR---------------CARAARCARGARYTNAGYGARMGNGCNGAYAGYGGNTTY GARMGNTCNAAYGARYTNMGNCARCAYGGNACNAAYGARGARGARAARGARAAYYTNGAY GTNYTNAAY---------AAYAAYATGCCNYTNGARGARGAYTAYGTNATHGTNGAYCCN CCNTTYGCNAGYGARGAYGAYCCNMGNGAYGTNAARACNTTYYTNGGNGTNATGTTYMGN GCNCCNCAYYTNTAYGAYYTNCARGAYAGYMGNYTNACNGTNGAYGAYTAYYTNAAYGAY GTNGGNCARYTNGTNTCNMGNYTNGARGARGAYATGCCNATGYTNGAYGARTTYTGYCAR TCNGTNATHGARTTYACNAGYACNGARGAYGARGAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CCNTCNCCNAAYGGNGCNATHCCNCCNCCNGCNCAYTCNCARCCNMGN AARMGNACNTAYCCNTTYGAYTCNCARGGNAGYYTNTTYCCNAGYCCNGAYATHGTN--- ------------------------------------------------YTNGTNCCNYTN GCNGCNTCNATHCCNATGATHAARGAYATHATHTCNGTNTTYTTYMGNAARYTNGTNTCN YTNYTNGAYGARGGNAARGTNYTNCARAAYTCNGARYTNTCNAARAGYTTYYTNGARTGY YTNAARAGYTTYTGGTCNYTNTGYTCNMGNCARCARAAYATHGTNACNTCNTCNCARTCN TTYGGNAARTGGCAYCCNAARYTNYTNGARGARATHACNCCNYTNGCNTCNGTNTTYACN GAYYTNTTYATHTCNGCNTAYGGNCAYAAR------GARGAYMGNGCNYTNTGGTCNMGN MGNYTNTAYAGYTGGYTNAAYTTYGAYYTNCCNGAYMGNGCNATHAARGTNGCNYTNYTN GARGCNGARGGNCAYGAYAARGAYGGNGCNGARYTNGTNGGNCCNYTNYTNMGNCARGTN YTNCARMGNAARTTYGAYAGYTCNTCNAAYCCNGARTAYYTNYTNCAYTTYYTNYTNYTN AARAARTGGCARGGNYTNTCNTCN---YTNTCNGAYATHAARGARGTNTCNAARTTYYTN AARGCNCCNACNTCNTTYYTNGCNTGGYTNAARACNTAYTGGACNGCNGGNACNAARTAY ATHCCNCARGAYACNYTNYTNGARGGNGCNGARGTNAGYCARTTYYTNYTNCARYTNAAR ACNGARAAYGTNYTNGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNAAYMGNCAYAGYCAR GARAAYGGNAAYTGGGCNATGTTYGARGAYGARGARAGYCAYATGYTNATHGGNTCNGGN GTNAARCARCAYTAYAAYAGYYTNGARCCNCCNAAYTTYGAYTCNTCNTCNATHTCNTCN GARGCNGARAGYGTNGAYGAYATHTGGTCNATHAAYGARGARCARMGNGARTAYTAYATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARCCNCCNCCNTTYAAYAAYYTNAGYTCNACNTTYCCN GCNGGNCCNATHTTYCCNGAYGCNACNCARCARATHCARYTNAGYGTNCCNACNGTNACN TCNCAYGAYGGNAARTTYCARYTNACNATGCCNATHGAYGAYTTYAARCCNGARGAYYTN ACNGTNAARACNCARGAYAARAARGTNATHATHTGYGCNAARMGNGARGTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARTTYACNGAYGAYGARATH MGNCARGARYTNGCNCARYTNGGNTAYCAYGAYGTNCCNMGNGAYAARYTNGARGAYTTY AARAARGAYYTNATGGCNYTNATHTCNAARGARMGNAGYAARTCNACNTCNYTNAAYAGY AGY---------------CAYGCNTCNGAR---ACNGGNMGNGGNATGAARGCNMGNCAR GARGGNCARTTYCARACNGARGAYTTYACNAGYTAYGGNCARCCNTGGACN---GGNCAY MGNYTNAAYGARGAYTGGCAYTAYGGNGGNGARAGYGGNCCNAGYCCNMGNCCNAARACN GCNCCNGCNGGNMGNGAY------------------------------------------ ---------------------------------------------------------TGG GAYTTYYTNAAYGARGAYTAYGAYGARAAYCARAGYTGYAAYCAYGAYGAYGCNTCNGAR ACNAAYTCNGARACNMGNTTYATGAARMGNAARACNTCNMGNAARACNCCNAAYGGNTGY MGNYTNGTNGAYGARTCNTTYACNGAYACNGARTCNGGNGTNTTYGARATHTAYGARAAR ATHAARAAYYTNGCNATGMGNGARTGYGARTGYGGNAARACNMGNACNAARTCNGGNGAY GTNGARCCNCCNTAYMGNATHAARGGNAARCCNAAYAARTAYCCNTCNGTNATHMGNAAR YTNGARCCNCCNCAYACNMGNAAYYTNGTNAARACNGAYGTNAAYGARMGNCAYAAYATG TAYAARGARGCNTGGMGNACNCARCCNCCNATHGGNGARGAYCAYMGNATHCCNGTNMGN AARGCNATGCAYAGYMGNYTNATGAARCAYGARGARGTNAARATGAARCCNAARGTNTAY ATHCCNAAYATHTAYGTNCCNCCNCAYGARAARYTNMGNAARGAYGTNMGNTGGAARGTN MGNCARGCNTTYGARAARTAYGARYTNCCNGCNCAYGGNTTYTAYCAYGARAGYYTNACN AARGAYTTYGAYMGNGCNCARAARACNATHACNCARYTNCAYYTNGCNAAYAARGARTGG AARAGYTCNTGGGAY---ATHYTNCARAARCARAARGAYGAYAARGARCARYTNMGNGCN CARATGAAYAARGTNGTNCAYGARAARGAYCARATGATHMGNGAYATGGARTAYMGNATH ACNTCNCARAARATGGARYTNAAYCARACNAAYYTNYTNAARAARGARGCNGARAARTCN TAYYTNACNYTNYTNACNGGNMGNGCNCARGARAARCARYTNYTNGARAARYTNAARCAR GAYTAYGGNACNYTNCAYCARGAYAARMGNGCNYTNGARGTNCARYTNGARATHGCNCAR GCNAAYAARCCNACNGARGARYTNMGNCCNACNGARATHTCNTCNGARATGGARACNGAR YTNGCNGTNATHAARMGNCARGTNACNYTNTAYYTNGARGAYTTYGARAARGARCAYTCN GARMGNYTNGTNGTNGARAARMGNYTNCARAARGARAARGARTCNTCNCARAGY------ ------YTNGARACNAARYTNMGNAARACNCAYTCNYTNYTNAARTCNMGNGAYGARGAR YTNMGNCARAARTCNAARYTNGTNGCNGAYYTNCARTTYGARGTNGCNGAYATHAARYTN AARYTNGARATHGARCARMGNMGNGCNTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AAYCARGCNYTNGTNGCNATGYTNAAR TCNTGYTGYCARAAYAAYACNGCNYTNGCNACNACNGTNMGNGCNCAYATGGTNTCNATH YTNTCNGARGCNGGNGAYGAYGAYAARGAY---TCNYTNGCNGGNYTNATGGCNTGGATG CAYGARAAYTAYGTNGGNMGNGARGAYYTNGAYAARAARYTNTCNYTNGTNGCNGCNGGN ATHACNGARAAYYTNCARGCNYTNYTNGCNGARMGNGTNGCNAGYGARATHAARGCNTCN ATHGTNTCNGCNAGYATHGAYGARATGGTNGTNAARTCNATHGTNGARGARGCNYTNGTN CARTTYAGYGCNGAYMGNGTNGGNATGCCNGAYTTYGCNYTNGARTCNGCNGGNGGNAGY GTNYTNAGYGTNMGNTGYTCNGARACNTAYTAYMGNAARACNGCNYTNGTNAGYGTNTTY GGNGTNCCNYTNTAYTAYACNTCNAAYTCNCCNMGNACNGTNATHCARCCNAAYGTNCAY CCNGGNGARTGYTGGGCNTTYAARGGNGAYTAYGGNTTYGTNGTNATHCARYTNTCNCAR CCNATHCARCCNAAYGGNTTYACNYTNGARCAYATHCCNAARAGYYTNGCNCCNTCNGGN ACNATHGAYAGYGCNCCNAARGCNTTYACNGTNYTNGGNYTNAARGCNGARGAYGAYYTN GARGGNATHAGYTTYGGNAAYTTYACNTAYYTNGAYAAYGGNAARCCNATHCARCAYTTY TCNGTNCARAAYCARCAYCCNGGNGTNTTYCARTAYATHGARYTNMGNGTNATGAGYAAY CAYGGNAAYCCNGARTAYACNTGYATHTAYMGNTTYMGNGTNCAYGGNYTN--------- ---GARTAYCARTGYCCNTCNMGNYTNACNCAYMGNYTNTCNCARYTNGTNATHGTNGAY AARCARACNAAYAARTCNGAYTAYCAYYTNCCNYTNGCNAAYACNGTNATHACNTCNYTN ATHGAYCCNCARMGNYTNAAYGARATHTCNGARATHAARGAYCCNTCNTCNCAR------ ------CAYACNCCNGTNAARGARGCNAARGARATHATGMGNATHMGNCAYAARAARATG AARAARCAYAARYTNAARAARYTNMGNAARMGNATGTAYTTYGTNTGGMGNAARGARAAR YTNACNMGNAARGCNAARMGNGAYGCNATHTAYTGGAARGARGTNTCNGAYATHAARAAR GAYGGNGAYGAYTTYAAYGCNGARACNTTYGTNAARGGNCARYTNGARAARGCNMGNMGN GGNGGNTAYTGYATHAAYGTNTTYGAYTCNAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARATHATHACN GCNYTNAARTCNTCNATHYTNYTNYTNGTNGTNAGYTTYGTNTAYCAYTGYATHGCNGTN YTNTTYGGNGCNCCNGTNTTYACNTTYGTNTCNGARACNTAYCAYTTYGCNATHYTNATG ACNGTNYTNACNGGNYTNCCNATGTGYGCNGTNGCNGGNCCNMGNYTNGAYAARTGGATG GAYATHTTYACNACNGAR---MGNGARCCNGGNYTNCARACNGTNGTNTAYYTNACNACN ATHGGNGCNYTNYTNGGNGCNTGGATGGGNGCNATHCCNATHCCNYTNGAYTGGGAYMGN CCNTGGCARAAYTGGCCNATHAGYTGYTCNGTNGGNTGYGTNTCNGGNTAYTCNYTNGGN YTNTTYATHGCNTCNYTNTAYYTNCCNCAYCARTAYAARGCNYTNYTNAARCCNAARYTN ATHYTNGTNATHCCNGGNAAYCCNGGNGTNCCNACNTTYTAYAARGAYTTYATGMGNGAR YTNTAYGARCARTCNGAYGGNCARATHCCNGTNTGGGCNGTNAGYCAYGCNGGNCAYTCN MGNCCNCCNGAYGARACNYTNTCNTTYAGYGAYGTNTTYGCNACNAAYGAYAARAARTAY GGNYTNGARGCNCARATHGAYCAYAARGCNACNTTYATHAARGAYTAYATHCCNCCNGAY GTNAARGTNATHYTNATHGGNCAYTCNATHGGNTGYTAYTTYATHYTNAAYGCNYTNGAY AARYTNCCNGTNCAYCAYGTNCARMGNTGYTTYYTNYTNTTYCCNACNATHGARMGNATG GCNGTNTCNCCNAAYGGNYTNACNYTNACNCCNGTNTTYMGNTAYYTNMGNTGGATHATH GTNTTYTTYACNTTYTTYTGYATHYTNYTNCCNATGACNYTNMGNGARAARATHGTNCAR TTYATHTAYMGNAARATHGAYTAYCCNCCNTGYATGGTNCAYTCNATHYTNTCNACNGTN ACNCCNTGGACNACNAAYTTYTCNACNTTYYTNGCNAARACNGARATGAAYAARGTNACN ACNYTNCARAARGAYYTNGTNMGNAARCAYYTNAAYAARYTNAGYYTNTAYTAYGGNGCN MGNGAYYTNTGGTGYCCNGTNGARTAYTAYAARGARATHATGGAYGARTTYCCNACNATH GAYGCNMGNYTNTGYGARYTNGAYATGAARCAYGCNTTYGTNATGGTNGARMGNGARGGN MGNCARATGGCNAARATHGTNTGGGARTGGYTNGARTCNCAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GAYAARTGG TAYGCNTGYYTNGCNCARYTNACNATHGARGARYTNAAYGARGTNCCNTTYYTNGGNGAR AGYAGYATHTCNAARTAYCCNGARTGGCCNTGYTCNTTYYTNCARGARTCNAGYCARYTN GCNAAYYTNMGNAAYGAYAARYTNAAYGCNGCNGARGTNAARACNGTNGARATHAAYTCN GARATGGCNMGNGGNATGAARAGYAARAARYTNCAYGARGTNACNMGNATGGCNTCNYTN GTNCARGARATHATHACNGARACNAAYTGYAAYGTNGTNATHGAYGTNGGNTCNGGNYTN GGNTAYYTNGAYCAYGTNYTNCAYCARAARTAYGGNATHMGNGTNYTNGGNATGGARACN GTNCARAGYCAYGCNTCNGCNGCNGARMGNMGNGCNGTNAARCARGGNATHACNTGYGAY GGNATHMGNACNYTNCARTGYCAYYTNGARGAYAARGARGARTCNTAYAAR--------- GCNTTYATHMGNGARCAYATHAARGCNATGTGYTGYGTNTGYTGYTGYTAYCAYAARATG GCNTTY------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNAAYGARAARTTYGARAARTTYCCNYTN AGYGAYYTNGGNCARMGNYTNTGYTCNCARATHYTNCARGARAAYGGNAAYGCNTTYATH ACNCCNTTYACNYTNMGNYTNGGNGCNCARGARACNMGNTGYMGNTGGCAYCARCARACN AARATHGAYCAYGARAAYCAYATHAARCAYGTNGCNTTYMGNGGNYTNYTNAGYYTNACN GAYGARGAYGARGGNCAYATHMGNCARAARGTNMGNCAYTGYAAYTTYGARTCNATHCAR AAYTTYGTNGAYTCNTTYTAYGGNYTNCCNTCNGARGAYYTNGCNACNACNGARAARMGN AAYCAYYTNYTNTCNYTNTAYGAYCARAAYAARAARGAYTTYGAYGCNATHGARATHYTN ACNYTNYTNCARGTNATHYTNCARCCNGTNATHGARACNYTNATHTAYGARGAYMGNGCN CARTGGYTNMGNGARCARGGNCAYATGAAYGTNAARGTNYTNCCNGTNTTYGAYGARYTN ATHTCNCCN--------------------------------------------------- ------------------------------------------------------------ ---------------------AAYGTNTGYMGNCARYTNGAYATHYTNTCNGARYTNTTY TCNMGNCARTGYAAYGTNATHGTNGCNCARMGNATHMGNMGNTCNTAYCARATHYTNATG YTNTAYMGNAAYYTNTAYGGNGARTGYYTNYTN--------------------------- ------------------------------------------------------------ ------------------------------------------AARGARAARGTNMGNTCN CARTTYACNMGNYTNAARMGNAARTCNGAYGARGARATHAARMGNTGY------------ ------------------------CAYCARGARATHAAYGARTGGGARCARATHGTNGAY AAYGAYGAYTTYAARGTNTGGMGNMGNCARYTNCCNAAYTCNCARYTNTAYAARTAYMGN GTNYTNGGNCAYTTYAARGAYATHCCNGCNMGNGCNTTYTAYAAYACNCARGTNGAYGTN CAYTAYTGGAARGAYTGGGAYGCNCARACNATHGAYGTNCAYATHGTNGAYMGNGAYAGY AAYACNGGNTCNGARGTNATHCAYTGGYTNTAYAARTTYCCNTAYCCNATGTAYCCNMGN GARTAYGTNTAYGTNMGNMGNTGYACNATHTAYCCNGARAARAAYGCNATGATHATHACN GCNMGNGCNACNCARCAYCCNAARTGYCCNAAYAARAAYAARAAYGTNMGNATHGARACN TAYTCNTCNCARATGGTNATHACNCCNTAYACNTTYTTYGAYGARGAYGGNTTYTCNTAY GTNATGTCNTAYTGYGAYGAYCCNCARACNAAYTTYCCNCCNACNTGGTAYAAYTGGGTN GCNAGYTCNGGNGTNCAYGARTTYYTNCARMGNATGCAYMGNGCNGCNATGAARAARCAY GARAARACNACNGTNGAYTAYGCNTCNAAYMGNATHGARAGYGGNCCNTCNAAYYTNTAY CCNGGNATGGTNCAYATGYTNYTNMGNYTNAARGARGTNGTNCARTGGACNMGNATGACN GCNYTNGARYTNATGYTNCAYYTNATHTCNGTNYTNATHTTYTCNYTNYTNGTNGCNATG AARGTNGARGGNGAYATHAAYGTNTCNTGGCCNGTNATHTTYTCNCCNYTNTTYATHTGY GAYGGNYTNAAYGCNTAYYTNTGYGTNATHATHTTYGTNMGNCARTAYMGNGARTAYGAR YTNAARCARGCNTGYYTNMGNYTNTCNAAYTCNYTNTCNGTNATHGCNYTNATHTTYACN TTYAARYTNYTNYTNTGYCARAARYTNGARAAYGGNGGNYTNAGYTGYTCNGARGTNTTY GCNCCNATHTTYGTNYTNTCNCARGTNTTYATGTTYMGNGCNTGYMGNATGCAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATHAAYYTNACNGTN--------------- ---------------------------------------GARGARGAYGAYYTNTTYTCN GAYGCNAARGARAARCCNTCNTCNCCNGAYACNGTNAGYCCNCAR------TCNGTNAAY GGNACNGAYGARAAYCCNTTYGGNAGYGAYGARAARGARGAYGAYGAYYTNTTYAARGGN GGNAGYTCNGARATHAARYTNGARTCNGAYGAYGARGAYGTNTCNGAYGTNAAYAAYAGY GARTCN------------------------------------GCNCARCCNGARGARCCN GCNATGGCNGCNTCNTCNAAYAARGARGTNACNCCNGARATHTCNGTNTCNGARGTNATH ACNGCNAARACNAARATHGCNGCNCCNTCNYTNAARTCNGAYGARATHTCN---GARGAY AAYGAYGARAARGARCARTAYGARYTNGAYATHAARATHACNGARAAYYTNAARATHGGN GAYGGNATGTCNGCNTAYATGGTNTTYAARATHGTNTCNAARACNGCNAAYCCNGCNTTY MGNCARCCNGARAAYGCNGTNYTNMGNMGNTTYAGYGAYTTYYTNGGNYTNTAYTCNAAR YTNGCNGTNAARCAYGTNCCNYTNGGNATHATHGTNCCNCCNGCNCCNGARAARAGYGTN ATHGGNATGACNAARGTNAARATGTCNAARGARGAYACNGGNTCNATHGAYTTYATHGAR MGNMGNAARGCNGCNYTNGARMGNTAYYTNATHMGNACNGCNGCNCAYCCNGTNYTNGCN GCNGAYTCNGAYTTYATHGARTTYYTNGARAARGAYGGNGAYYTNCCNAARGCNACNAGY ACNTCNGCNYTNAGYGGNGCNGGNGTNATGMGNYTNTTYCAYAARGTNGGNGARTCNATH GARAARATHACNYTNAARGTNGAYGARAGYGAYGARTGGTTYGARGARAARCAYCARCAR ATHGARGCNYTNGAYYTNCARYTNAARAARYTNCAYTCNAGYYTNGARACNYTNGCNGCN CAYMGNMGNGARYTNTCNGGNAGYACNGCNGTNTTYGCNAARAGYGCNGCNATGYTNGGN AAYGTNGARGARCAYACNGCNYTNTCNMGNGCNYTNTCNCARYTNGCNGARACNGARGAR AARATHGARATHGTNCAYAARGAYCARGCNGARGTNGAYTTYTTYACNATGTCNGARYTN ATGAARGAYTAYGTNGCNYTNATGGGNGCNGTNAARGGNGTNTTYCAYGARMGNATHAAR ACNTAYAARCARTGGAARGAYGCNGARACNATGYTNGGNAARAARMGNGARAAYAARGCN AARYTNGARATGCARGGNAARGCNGAYAARYTNTCNCARGCNMGNACNGARATHACNGAR TGGGARCAYAARGTNGARAARGGNCARGARGAYTTYGARAARATHTCNAARAAYATHMGN AARGARGTNGTNMGNTTYGARAARYTNMGNGTNTCNGAYTTYAARACNAAYGTNATHAAR TAYYTNGARGTNYTNATGGARAAYCARGARAARYTNATHAARTAYTGGGARACNTTYYTN CCNGARGCNAARGCNATHGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARTGYCCNTAYGARGGNTGYAAYAARACNTTYCCNTTYCCNACNGTNYTNMGNMGNCAY ATGAARGTNCAYCARGGNTAYGARTGYGAYATHGARGGNTGYGGNGARGTNTTYGARACN TAYYTNAARYTNMGNAARCAYAARGCNGTNGARCAYGGNCCNGAYYTNGTNTGYMGNCAR TGYCARACNCCNTTYAARTCNMGNCARACNYTNGTNCARCAYYTNAARACNCAYYTNTTY GTNAARGARGTNTTYGTNTGYACNGARGTNGGNTGYGARMGNACNTTYYTNTAYAARAAR AAYYTNAARCARCAYATHMGNGCNTAYCAYYTNGGNGARAARGTNTTYACNMGNAARAAR ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNCCNTCN GARGGNCCNMGNGARGAYYTNATHAAYACNGCNGTNAARTTYYTNCARAAYCCNAARGTN ATGGGNAGYCCNYTNAAYCARAARAARGCNTTYYTNACNAARAARGGNYTNACNCARGAR GARATHAAYYTNGCNATHGARMGNGCNGGNGTNACNGARACNAGYACNGCNCCNAGYAAY GTNAAYCARGCNMGNCCNCCNCCNCCNGGNTAYCARCCNGGNATGATGACN--------- ------CCNTAYGGNCARATGCAYCCNCCNATHCCNCCNCARTCNMGNTGGGCNCARGCN MGNGAYYTNACNYTNACNTCNGTNGTNGTNGTNAGYGTNTCNTAYGCNGCNTAYCAYYTN TAYAARACNTAYATHGARCCNYTNATHMGNGGNAARACNGTNCARGARAARMGNYTNGAY MGNYTNGARYTNCARGTNGARGARATHCAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATHATHACNGAYGTN GTNGAYGGNATGACNGAYTGYCCNTTYGAYTAYTCNYTNGTNATHGAYAAYGCNGGNAAR ACNACNATHACNACNAARGARGCNGTNTCNGAYTCNYTNACNTGGGCNAARYTNGARAGY AARMGNGARACNACNGTNGCNGARTTYATHCAYGGNGTNCARGCNGGNATHGGNAARGAY GTNYTNTTYGAYTGGAGYYTNCCNATHCAYTGYCCNAAYYTNGCNCARAARATHTCNYTN CCNGARTAYTTYAARAAYAAYATHYTNYTNMGNACNACNCCNGGNTCNYTNTAYMGNGAR AGYTGGCCNAGYYTNTTYATHGCNCCNAARGGNGCNGTNACNCARYTNCAYATHGAYGCN TTYCAYTCNCAYTTYTGGATGGCNYTNTTYCARGGNGARAARAARTGGACNTTYTTYGAY GGNAARGAYACNGCNTTYYTNTAYCCNCARTGGTTYCARTCNATGGAYCCNGTNTTYGAR GTNGAYYTNACNCARCCNGAYYTNACNCARTTYCCNYTNYTNGCNYTNACNCAYCCNCAR CARTGYGTNYTNCARAARGGNGARYTNYTNTTYGTNCCNGCNGGNAGYCCNCAYTTYGTN GARAAYYTNACNCCNACNYTNGCNATHTCNTCNAAYTAYGTNGAYCAYTCNAAYTTYAAR MGNGTNTGYGARGARYTNAARGTNAAYTCNTTYCARGAYCARMGNGCNCAYGAYYTNYTN TCNCARYTNCARGAYCCNGCNTTY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARAAYATGATHYTNGCNAAYMGNMGNGTNMGN CARACNGAYATHGCNAARGARGTNGGNATHTCNAARGARMGNGTNCAYCAYATHGTNACN GTNATHYTNGGNTAYMGNAARGTNTCNGCNMGNTGGGTNCCNMGNATGYTNACNGGNGAY ATGAARYTNAARMGNCARCARATHGTNACNGARTCNTGGGTNTCNATHGARTAYMGNCAY AARAAYTCNCCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARCAYTAYGAR GGNAARGCNGAYTCNGGNGTNTTYGARAGYCARCCNGARAAYATGCCNGAYGTNGTNAAR TCNGGNGARAARYTNGCNCARGAYGCNGTNCCNGARMGNGGNACNGCNAARAAYYTNGCN CARMGNTTYCAYCARATHTCNATHGARAGYGCNGCNAGYAGYGCNGGNMGNAAYAARMGN GARYTNACNCCNGAYCARAGYGGNMGNAGYGARTAYGTNAGYGARCCNMGNTCNCARGTN GARTCNTAYGARAGYAARGTNGARTCNGGNGTNTTYGARAAYACNCCNYTNGARGAYACN GARGTNGTNAARTCNCARACNGCNGCNGARGARTAYGTNCCNGARMGNGGNTAYACNAAR AAYGTNGCNGCNAARTTYAARGARYTNGARAAYACNGCNAARTCNCCNCCNYTNTCNCCN GGNMGNMGNAARGARTTYACNCCNCCNMGNGARGAYGTNACNAGYMGNAAYTCNGGNATH TAYGARAGYACNCCNGARACNAARCCNGAYGTNGTNACNTCNTCNGARTCNCARCARGAR GTNATGCCNGGNGCNGGNACNGCNMGNTCNYTNGCNCARMGNTAYAARGARATHGARGCN CARAGYAARTCNCCNGTNGCNTCNAARCCNAARAARGARATHACNCCNCCNCCNAAYGAR GCNGGNGTNTTYGARAAYAARCCNGARMGNTTYCARGCNGAYTAYAAYMGNCCNGCNGAR TCNGGNATHYTNGARAAYACNCCNTCNGCNCARMGNGAYGAYGTNYTNAARGGNAGYGAY ---GGNAAYACNGARGTNGARYTNCCNGARGCNGGNTCNGCNMGNAAYYTNGTNAGYAAR TGGMGNCARATHGARTCNGARAGYGCNAARAAYACNTCNCCNGGNTCNGCNGGNMGNCAY AARGCNTTYACNCCNCCNMGNGARGARCCNMGNATHATGCARAAYAGYAARTCNCCNMGN ACNCCNAARTCNCCNACNGCNCARYTNGAYAAYGGNGCNGTNCAYCCNTCNGARYTNCCN GGNCARTAYCARCCNCARAAYGARCCNCAYGTNTTYGARTCNAAYCCNGARCCNCAYCCN GAYGCNYTNMGNGARGCNGAYACNGAYAARAGYCAYGGNYTNCCNAARAARAAYCARGCN AARAARATGYTNGCNMGNTTYCARAGYATHCARGAYGARGCNAAYAARGARACNCCNAAR CCNGTNCCNAARAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TAYGCNCAYACNAARCARTCNCARCARAGYGGNCAYAARAARATGCCNTCN GCNMGNYTNACNYTNGGNCAYGCNGTNGCNAARTCNMGNATHYTNTTYTCNMGNAARAAR AARGAYAARGARGARGARATGAARMGNMGNAARAAYYTNCARGARGARTCNTAYGARTTY ATGMGNGGNGTNATGGAYGARTGYACNCAYYTNGCNAAYTTYTCNGTNCCNGTNGAYCCN GARYTNGTNATHATHGTNTCNGCNAARCARGAYGCNTAYATHCCNMGNGAYGGNGTNYTN CCNYTNGAYAARYTNTGGCCNGGNTGYGARGTNMGNTAYATHGAYCARGGNCAYGTNGGN GCNGTNYTNYTNCAYCARAAYGTNTTYMGNAARGCNGTNACNGAYGCNTTYGAYAARCAR ATHCARAARTAYMGNGAYAGYAARATHYTNACNGAYTAYMGNGAYTAYYTNAGYGAYTCN GGNGTNCARAARMGNGTNTTYTCNAARGARACNMGNGAYMGNYTNATHAGYMGNGTNGAR AAYTCNATHTCNCCNGAYYTNMGNATGYTNYTNTCNGAYAGYAAYAAYAARATHTCNATH CCNGCNAGYATGAAYMGNAGYGTNAAYACNAARGTNATHMGNTCNTCNATGAGYCARAAY ACNMGNGAYAGYGTNTTYTGYAARTAYACNCAYMGNAAYTGYACNCARAAYTGYYTNGAR GGNTAYGAYTAYTGYATHMGNCAYATHYTNGARGAYAARACNGCNCCNTAYMGNCARTGY GCNTAYATHACNAARGCNGGNAARAARTGYCCNTCNGCNGCNCCNAARYTNGARAARAAR GARGGNTTYTGYGCNTTYCAYACNAARAARGCNCARYTNGCNMGNCARMGNYTNGCNMGN AARMGNMGNCCNAARGARACNCCNGAYAGYYTNYTNGARGAYYTNGTNGTNACNACNTCN ATGATGGAYTCNAAYCAYAGYYTNGARCCNMGNMGNGGNAARGTNCAYAAYGAYAGYATH GCNTCNMGNGCNYTNGAYTAYGCNAGYTCNAGYGAYTCNGARGCNGARCCNYTNYTNGTN GAYCAYGCNTGGMGNGAYYTNGGNGAYAGYGAYGCNGARAGYATHGAYAGYGAYCARGAR GAYGTNYTNAARTAYGCNGGNGTNTAYACNACNGARGARGTNGCNCARATHYTNMGNGAY AARYTNATHMGNYTNCARGCNYTNTAYATHGAYCARTTYAARMGNYTNAARCAYATHYTN TTYACNAARMGNMGNAARTAYYTNCARGCNCARAARAARGARAARGAYATHTTYGGNAGY YTNAARMGNTAYAARGAYGAYCCNCAYCARMGNGARAARTAYAARAARYTNTGYGCNATG AARMGNTAYCAYAARAARTTYGGNATGGARGCNYTNGTNCARCAYCARTCNACNCAYMGN MGNYTNAARGTNACNGARGGNATGAGYCAYMGNCCNCARGCNCCNGTNCARTGYAGYTTY GARGAYGARGGNYTNMGNTGYTCNCARACNGTNGTNCCNYTNAGYAARTAYTGYCARAAR CAYATHYTNCAYGAYCARAAYCARGTNYTNTAYMGNCCNTGYCCNTTYGCNGAYAGYCAR TGYGGNMGNCCNGTNCCNTCNYTNYTNGGNAGYCCNTTYTGYTCNYTNCAYCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AARGAR MGNGTNCARACNYTNGARGTNGCNGTNGCNGARAARGAYTCNGCNYTNACNCARGCNAAY GARYTNYTNAAYAARCARAARACNGAYATHACNGAYATHCAYTCNAARYTNAARGARAAR CARAAYYTNGAYGAYGAYTTYACNMGNGCNCARGAYATGATHAARTCNYTNGAYAARGAY GTNTCNGARYTNAARGTNAGYAAYMGNGAYYTNCARAARGAYATGGARTCNTGYMGNGAR MGNGARTCNAARATGYTNGCNYTNCARTCNGARYTNAGYMGNACNAAYGCNTGYYTNMGN TCNGARAAYACNACNYTNAGYAAYAARGCNACNAAYCARACNGCNGARGTNGARMGNYTN AARATGGARATHCARGARYTNGARACNACNGTNAARCAYYTNTCNGAYTCNGTNGARGAY GARAARAARAAYAAYTCNCARGCNATHGTNAARYTNAARTCNTCNYTNGARGARAARACN AARGARAAYAGYGAYTTYAARCARAARTGGGARGAYGARATHGAYTCNAAYAARACNYTN AARMGNMGNCAYGCNAAYAAYGTNAARGAYYTNACNMGNCARYTNCARCARGCNAARMGN MGNYTNGARATHGTNGARGGNAGYMGNAARGAYAGYGCNGGNAGYATGGGNTCNMGNACN AAYTCNAAYGGNAGYYTNAAYTCNATG--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARTCNAAR AARAAYGGNGAYGARAGYTAYCARACNTTYATHYTNCAYGAYGARGAYCAYACNYTNGGN AAYGCNYTNAARTAYATHYTNAAYAARAAYCCNGAYGTNACNTTYGTNGGNTAYAGYATH ACNCAYCCNTCNGARAGYAARATHAAYYTNMGNATHCARACNTCNGGNAARCCNGCNATG CARGTNYTNAARCARGGNTTYAARGAYYTNCARAARYTNTGYGGNCAYATHYTNACNACN TTYGARTCNTCNACNAARTAYTAYAARGARAAYCAYATGGAY---CARGCNGAYATGGAY CAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARGAYGAYCCNGTNGCNTGYAGY CARATHGTNAARYTNTCNCCNYTNGCNATGTGGGAYYTNGARCAYTGYGAYCCNAARAAR TGYACNGGNAARAARYTNAGYMGNGTNGGNTTYGTNMGNACNYTNMGNYTNAAYCARMGN TTYAAYGGNYTNATHYTNTCNCCNATHGGNACNAARTGYGTNGCNCCNGAYGAYMGNAAY ATHGTNGARATGAAYGGNGTNGCNGTNATHGAYTGYAGYTGGGCNAARYTNCARGAYACN CCNTTYGCNMGNATGAARGGNGAYCARYTNMGNYTNYTNCCNTAYYTNATHGCNGCNAAY CCNATHAAYTAYGGNAARCCNTGYAARYTNTCNTGYGTNGARGCNTTYGCNGCNACNYTN TAYGTNACNGGNTTYGCNAARGARGCNGARACNYTNYTNAARAARTTYAARTGGGGNMGN TCNTTYTCNACNYTNAAYAARGARYTNYTNGAYACNTAYAGYAARTGYCAYACNAGYCAR GARGTNGTNTCNGARCARGARAARATHYTNGCNCARYTNGARGARGAYGGNMGNCARAAY AARATGAARGAYTGGATGGARATGGAYYTNGAYACNGAYGTNTGYAAYCCNAAYMGNCCN ------ACNGARTCNAGYTCNGARGARGARAGYGARGARGARAGYGARGARGAYGAYMGN TGGGAYAARGAYAAYGAR---------------------------------GARYTNGGN CARAARATHGGNATGGARTGYGCNGCNMGNCAYAGYAAYCCNGARTTYYTNATGGCNGTN GCNAGYCAYATGGARAGYCCNGAYGAYATGGCNCARCCNACNTTYATHTGYGAYTAYCAR AARGAYATHGTNAAYATHYTNATGTGYGTNAARGAYGARYTNGCNAARTGYATGCCNGAR GARACNAARTCNYTNATG---GARYTNTTYCCNTCNAARGARMGNYTNACNGARGGNYTN MGNTTYATGTGYGARCAYAARGAYGTNYTNCARAAYAARTGYATGGAY---GAYCAYACN CARGARTTYATHCARTGYTAYATGGGNAARGTNACNAARYTNCARGCNTCNGTNACNGAY GTNTCNAAYGTNGAYCARYTNAARGGNYTNGTNTGYAGYGTNATHMGNTCNGARGARCAR TGYTTYMGNGAYAAYAARGGNTCNTGYAGYAARGARTTYGTNGAYATGGTNATHCARATG YTNGARAARTTYTTYCCNATGTCNCARTGYGAYGCNTCN------GGNAARAAYGAYYTN ATGAAYGTNYTNGGNAGYATHYTNGTNCAYGGN------------------CARCCNCAR GGNAGYYTNAARTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TCNAAYGARGARYTNGCN ATHAARAAYAARGARGTNATHAAYYTNCAYACNCARYTNCAYACNTAYCARGTNGAYATG GARAARAARAAYAARGARYTNGGNGARAARGCNAARGARYTNATHGGNTGYAARGARGAR GCNGARAARYTNAARMGNGARYTNGAYMGNYTNAARAAYCCNCCNGTNYTNTGYGARGCN TCNAGYCARACNCAYGCNYTNTGYGARGTNTCNAAYYTNGARAAYGTNAARCCNTCNATG ATGGGNGARMGNGARMGNACNATHCARACNYTNCARGARGARYTNAAYGARYTNMGNACN CARGTNYTNGGNATGGAYGARMGNCAYGARAARGARAARGARCARTGGYTNGAYGARAAR AAYAARGTNATHMGNTAYCARAARCARYTNCARYTNAAYTAYGTNCARATGCARMGN--- ------------------------------------------------------------ ------------------------------------TCNTTYTTYYTNYTNTTYTTYTCN YTNGCNGCNACNYTNAAYYTNGTNTGYYTNATHTAYATGYTNCARTGGYTNCCNACNGCN GARTCNTTYATHCCNTAYTTYGTNATHATGGGNGTNTGGGGNGTNACNGAYGGNTTYTGG ACNGCNCARGTNACNAGYYTNATGGGNYTNATHTTYCCNGAYMGNATHGARGARGCNTAY GCNGGNYTNMGNATGACNCARGGNYTNGGNGCNGCNGTNGCNTTYGGNTAYTCNAGYGTN TTYTGYATGACNGCNAARATHTAYATHACNGTNGCNGTNTGYTCNYTNGGNYTNGTNGGN TAYYTNYTNGTNGARGGNATGYTNAARMGNCARMGNAAYAARTCNGGNTTYYTNYTNAAR CARACNTCNGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AGYGTNGAYTAYYTNAARGGNTGYATHGGNGTNGGNCARYTN AARGTNTGYTAYCCNCARYTNGAYTTYATHCCNAGYGCNYTNTTYGCNATGGGNTCNCCN ATHGCNYTNTAYYTNTCNYTNMGNGGNATHGAYGARATHGGNGARTTYTTYCARYTNCCN ACNTGYCCNMGNGTNTTYAAYATHTTYCAYCCNTTYGAYCCNATGGCNTTYMGNYTNGAR CCNYTNATHMGNCCNTCNATGTCNCARGTNAARCCNGTNCARGTNCCNCAYTAYAARGGN MGNAARMGNYTNCAYYTNGARTTYAARGARGCNGTNAGYMGNTAYGGNACNGAYATHAAR CAYAARATHATGGARTCNYTNAARAGYACNTGGAAYAGYATHAAYGAYTTYGCNAARGCN CAYMGNGCNGAYGCNAARAAYATGGARAAYCARGTNCARTCNGARATGGAYCARATGATG AARCARATHTCNCARCARCAYGCNGAYGAYGAYGTNGCNTCNGTNTCNTCNATGGCNGAR GARGARATHCARATHGGNCARYTNAAYGARGGNCARMGNGTNGAYTAYCARYTNCARGAR GGNCCNYTNGARTCNTTYAAYGAYTAYYTNTTYGCNYTNACNTCNCAYTCNTGYTAYTGG GARTCNGARGAYACNGCNYTNYTNGTNYTNAARGARATHTTY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNCCNAARAARGCNGGNTAYGCNCARATHAARTCNGAR TTYYTNYTNCAYGAYTAYAARCCNACNATHCARACNGARTAYYTNAGYCAR--------- ------------GAYACNAARMGNAARYTNGCNGCNGCNAGYGARGARAARCARACNGAR GARGAYGAYGAYGCNGCNGAR---------CCNCCNAAYAARAARCCNAARYTNAARGGN MGNAAYAARCAYMGNCCNAARAAYGARMGNATHGARCARAARGAYMGNYTNTGYCCNTCN ATHAARAGYGARAARGARTGYMGNTTYGGNGAYAGYTGYMGNTTYAAYCAYGAYATHAAR GAYTTYATHGARAARAARMGNCCNGAYATHCARGARAARTGYCCNGTNTTYGARACNYTN GGNTTYTGYAARTTYGGNGTNACNTGYMGNTTYGCNAGYAGYCAYYTNGGNGARAAYCAR GARAAYATHGTNAAYAARGAYYTNTAYGAYACNATGAARGARAARCCNTCNTTYYTNAAY GCNYTNACNGAYGAYGTNMGNCAYAARYTNTGGAARMGNAARTAYGAYTTYTCNAARGCN ATGGARTCNGTNAAYAAYGTNCARAARGCNTTYAGY------------------------ ---------AAYACNAAYAGYACNGCNGCNACNCCNGTNTGYGAYYTNAGYGCN------ ---------------------------GAYYTNAAYAAYGAYYTNGTNACNAARGGNGAR ATGCCNCCNCCNGCNACNGARGCNGTNGAYYTNGGNCCNACNGTNTCNAARCCNTCNCAR GARMGNTGYCCNTCNGARGAYGGNATGAGY------------------------------ AARGTNGTNGGNGCNGAYAAYGAYGAYGTNCAYATHMGNTCNACNCCNMGNGARGTNAAR AARATHGAYTTYCAYAAYAARYTNTAYYTNGCNCCNYTNACNACNGTNGGNAAYYTNCCN TTYMGNMGNGTNTGYAARGAYTAYGGNGTNGAYATHACNTGYAGYGARATGGCNYTNGCN TCNCARYTNYTNAARGGNAARGCNTCNGARTGGTCNYTNATHAARMGNCAYCCNAGYGAR GAYATHTTYGGNGTNCARGTNTGYGGNGCNTAYCCNGAYYTNATGACNAARTGYGCNCAR GTNYTNACNGARTCNAGYAAYATHGAYTTYATHGAYATHAAYTGYGGNTGYCCNATHGAY YTNGTNTTYMGNACNGGNAGYGGNAGYGCNYTNATGGGNAARGTNACNAARYTNGARCAR ATHTGYMGNAGYATGMGNGGNGTNATGGGNGARATHCCNYTNACNGTNAARYTNMGNACN GGNGTNTTYGAYAARAARAGYACNGCNCAYACNATHATHCCNMGNATGMGNGAYGCNGGN GTNTCNYTNGTNACNATHCAYGGNMGNTCNMGNGARCARMGNTAYACNAARYTNGCNGAY TGGGARTAYATHGAYCARTGYGCNAAYYTNGGNAGYCCNATGCCNGTNTTYGGNAAYGGN GAYATHYTNTCNTAYGARGAYGCNAAYYTNCAYATGGCNMGNAARGGNGTNTCNGGNGTN ATGYTNGCNMGNGGNGCNYTNATHAARCCNTGGATHTTYACNGARATHAARGARCARMGN AAYTGGGAYATHTCNTCNTCNGARMGNYTNGAYATHTTYMGNTCNTAYACNAARTAYGGN YTNGARCAYTGGGGNTCNGAYCAYCARGGNGTNGARACNACNMGNMGNTTYYTNYTNGAR TGGYTNTCNTTYACNCAYMGNTAYATHCCNGTNGGNGTNYTNGARCARGTNCCNCARAAR ATHAAYGARMGNCCNCCNTAYTAYATHGGNMGNAAYGAYYTNGARACNYTNATGGCNAGY GCNAAYTGYGCNGAYTGGATHAARATHAGYGARATGYTNYTNGGNCCNGTNCCNCCNMGN TTYAARTTYYTNCCNAARCAYAARGCNAAYGCNTAYCAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AARGARTAYCARTAYACNTTYCARCAYGTNTTYGAYGARTGYGCN TCNCARAARACNGTNTTYGAYAARGCNGCNYTNCCNATHGTNGARGAYYTNYTNTGYGGN AARAAYGGNYTNYTNTTYACNTAYGGNATHACNGGNTCNGGNAARACNTAYACNATGACN GGNGTNCCNCARGAYCARGGNATHYTNCCNMGNTGYYTNGAYGTNYTNTTYAAYAGYATH GGNGAYMGNCARGCNAARAARTAYGTNTTYMGNCCNGAYCAYATGAAYGGNTTYGAYGTN CARAGYGARGCNGAYGCNATGATHGARMGNCARAARAARGAYATHYTNCCNGGNYTNACN TCNGGNAGYAARACNTCNYTNAARMGNGGNGAYGGNGGNGAYACNGARMGNATHGTNGAY CCNACNACNGTNGARGGNGTNGARGAYGAYAAYAAYTAYTCNGTNTTYGTNTCNTAYATH GARATHTAYAAYAAYTAYGTNTAYGAYYTNYTNGARGAYYTNCCNTAYAAYGCNATHACN GGNTAYMGNCCNCCNCARACNAARATHYTNMGNTCNGAYTCNTCNGAYAAYATGTAYGTN CAYAAYTGYACNGARGTNGARGTNAARCARCCNCARGAYGCNATHGAYGTNTTYTAYAAR GGNCARMGNMGNMGNAARGTNGCNCAYACNACNYTN------------------------ ------------------------------------------------------------ ---------------------------------ACNGAYTCNACNACNATHYTNGARYTN CARCAYAARATHAARGAYYTNGARTCNACNYTNTCNAARAARGGNGARGARYTNCARCAR CARGCNACNTCNYTNCAYGARCAYCAYMGNCAYAARGTNACNACNYTNAARGARMGNCAY ACNAARGARGTNAARTCNYTNAARGARAARYTNACNGTNYTNGARCARCARYTNTCNGGN GGNTCNCAYAGYGGNYTNYTNCCNGARTCNGAYMGNCCNAAYGTNAGYAGYAAYMGNYTN GGNGARATGGARAARYTNGCNACNGCNYTNAGYGARAARGAYAARGCNCARAAYGCNMGN GTNCAYYTNGARGGNGTNYTNGARGARYTNCARCARGARGTNGARMGNYTNCARAARCAR GARMGNGARGCNCARGAYAAYGAYGARGTNGCNTCNYTNCARACNCARYTNTCNGARYTN TCNMGNCAYTTYGARGARTCNCARGARGARAAYAARMGNYTNAARTCNGARAAYGCNMGN AGYAAYGARACNYTNGCNTCNYTNATGGGNGCNAARGARGARAARGAYGARGTNATGGCN MGNYTNGARGARYTNGTNTCNAGYATHGGNGAYGARGAYTGYCARMGNAARACNGCNGAR YTNYTNAAYYTNATHGAYAARGARAAYYTNATGYTNAARGARCARAARACNAARYTNGAR GARCARGTNGTNYTNYTNGARAARACNTCNTCNAAYCARATGAARGARAARCARTCNYTN YTNGARACNATGGCNACNYTNAARTCNGGNCARCAYGTNGTNCAYGAYGAYGCNACNTCN GCNACNGAYGAYACNYTNGAYTCNAARTTYACNACNTCNAAYGTNMGNGAYGARGAYATH GARGCNGARGTNGAYMGNYTNMGNTCNACNYTNGARAARATGAARGARGARTCNTGYAAR TTYGARACNGARMGNTCNGAYTGGGTNATGGARAARGARACNYTNGARGAYGTNYTNTCN GAYYTNCARAARMGNTCNAARGAYCARGARGAYGARATHATGTCNYTNAARTCN------ TCNGARGARTCNGCNGARACNACNAAYGAYMGNCARCARCARGARACNMGNATHCARGAR YTNGARAAYGARGTNACNTCNYTNAARGARCARAAYTCNGARYTNGARACNGCNATHGAR GARYTNGAYACNCARCAYTCNGARGCNYTNGCNCARYTNATHAGYCARMGNGAYAARATG GCNTTYCARYTNTCNGARCARGARACNGARATHAAYCARTAYAARACNCARATHAARTCN YTNAAYGARGCNATH---------CAR------------GAYMGNAARCARATHYTNGAR AARTGYCARAARTAYGARCARGARYTNATGYTNTGGAARGAR------AARTGYAARAGY ATGGARAARAARATHACNGARYTNAARGARAARYTNGARAARGGNGCNYTNGTNATHAAY GAYYTNCAYATGGAYAARCARGAYYTNGARGARCARYTNCARAARGCNCARGARGARATH AARGTNAARGTNTCNAARYTNAARGARAAYMGNGAYGAYAARGCNGCNYTNGARAARGAR AARMGNGARATHGARGGNAAYYTNMGNAAYTGYGARGAYMGNYTNYTNGARACNGARGTN GARYTNGARAARTGGCARCARYTNAAYGARGAYAARCARACNCARGGNATGGARMGNCAR CARAGYAGYCARGARACNTCNMGNYTNMGNTCNAARATHGARGAYATGAARCAYGARAAR GARGCNATHAARGARGARTTYCARTTYYTNATH---GAYGGNAARAARGARCARCARGGN GAYCAYCCNTCNGAYYTNAARGAYTTYCARCAYATHTTYGARGARGARYTNMGNGTNMGN CARAARYTNGARGARGAYGAYAARATHATHCARGARYTNAARGARTAYATHGARAARYTN MGNGAYGARMGNAARGGNYTNAARGARAGYGTNAGYGCNYTNAARTCNGAYAARATHGAR TCNGARTCNYTNTTYGARTCNYTNCARCARGARAARACNAARTTYGTNAAYCARYTNGCN GARCARACNGAYTAYYTNGARAGYAARGARTCNGARYTNCARGAR---GTNAARAAYAAR YTNGARAAYGTNTGYGARGARAARGARAARYTNMGNAAYGAYYTNATHAAR---YTNGAR AARGARAARYTNGAYATHGARAAYGCNTCNGTNAAYCARGARGARCARTAYAARTCNTAY ATHAARGAYGCNGGNCARGARGARTCNGGNAARGARMGNGTNGARATGAAYGTNGARATG GARMGNATH---------------------------------------AARAARCARATG AARGAYTAYGARGARGCNGTNACNGARAAYAAYCARGARAAYGARAGYYTNMGNGARGAY AAYGARYTNTAYAARGARGARGTNAARTCNACNAARGCNGARGTNTCNMGNYTNGARGAY GCNTGYGARGARAARGAYTCNGARATHGARTCNYTNAARGARGGNGTNGGNMGNYTNGAR CARGAYYTNTGYGARATGGARGARTCNGTNTGYATGGCNAARCARCARAGYGAYYTNGAR ATGCARAARAARGARGARGARATHAGYCARYTNAARGCNAGYAARGARGARTCNGARAAR MGNYTNAAYCARYTNMGNAAYCAYYTNGARTCNYTNAAYGARCARCARAAYGCNGAYGTN CARTCNCARAAYGAYGARTAYGGNATHGAYGCNYTNAARAAYGARMGNGAYGARAAYACN ATHTCNCARYTNGARACNGARYTNTCNGTNTCNGARGARAARATHGCNGGNYTNAARGAR GARYTNTCNMGNGCNATHAAYACNACNGARTCNCAYACNTCNYTNGCNTCNAGYGARAAY AARAAYTCNTCNGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GGNAGYAAYGARAGYGCNGGNATH GARGTNATGGARGTNGCNGTNTCNAARCCNYTNYTNACNTCNCAYCCNMGNACNGAYAGY CARGAYACNGAYTAYAAYGAYGAYGAYGAY------------------------GAYCAY GAYMGNTTYGTNGARYTNGARAARGARATGGARGARYTNMGNGGNMGNYTNATHGARAAR GAYGGNATHGTNTCNGAYYTNCARMGNTCNAAYTCNTCNYTNYTNGARYTNYTNGARAAR AARGCNGAYGGNGAYAGYAGYYTNGGNAAYMGNYTNGCNAGYCAYAARYTNGARGCNGAR YTNAARAAYYTNMGNGGNGARMGNGARCARATGGTNGCNGTNGTNAGYGARAARTCNMGN GARAAYTCNTCNYTNAARTCNGARATHCAYMGNYTNATGGAYYTNGTNGCNGCNGGNCAR GCNGCNYTNGCNAARGTNCAYCARGAYAAYGTNTCNYTNGARCARMGNCARCARTCNCCN CCNMGNGAY---------GARGARGAYGARATGAARMGNGARGCNYTNAAYAAYATGGCN MGNYTNGTNMGNGAYAARGAYACNGARATHGARGCNYTNACNCARAARAAYAAYACNYTN YTNGCNGTNYTNCARGAR---TCNAAYGARTCNAAYGCNGCNGCNCAYYTNGCNCCNYTN YTNAARGAYAARGARACNYTNACNCARCARATHAAYTCNATGYTNACNGARMGNGARCAR YTNATHTCNTGYGTNACNCARAARCAYTCNGARTCNYTNGCNTTYCAYGCNGARGTNCAR MGNYTNTCNGGNGTNYTNATGGARACNCARGARGTNGCNGARAARGCNAARGCNGARTAY GCNGCNYTNATHCCNTCNTTYGARGGNAARAAYCARGCNYTNYTNACNACNCARCARGAY YTNATHGARTGYAARCARAARYTNACNGAYYTNGARATHMGNCAYGGNGARYTNATGACN CARMGNTCNAAYATHCARCARCARAGYCCNAAYTCN------------CCNACNACNGAY GAYYTNGARGCNGARYTNGARAARTAYAARMGNYTNGARTCNGAYTAYAARTCNATGGTN YTNGARMGNGAYGARCARATHCAYAGYYTNTCNCARAARGGNAARGTNTTYGARGAYGCN GTNTCNTCNAARGARGCNGARTGYACNCAYYTNMGNAARCARYTNGARAAYTCNAARTTY CARYTNACNGGNYTNATGGCNGARATHGCNGAYGTNAARTCNGARMGNGARGTNATGCAR MGNAARMGNGAYAGYCARGGNGARGARTCNGTNAGYYTNMGNAAYAAYYTNAAYCARATG ACNYTNACNGTNAARGAYMGNGAYCARCARATHGTNTCNYTNAARGAYCARATHTCNACN YTNAAYTCNGTNYTNCARAAYCARAARGGNGAYGARGAYCARGTNAGYCARYTNATHMGN GAYCARGARYTNGCNGTNGCNGCNAGYMGNCARYTNCARCARGARMGNGAYMGNAAYGCN ATGYTNGCNGARCARMGNTTYCARGARTGYGARGCNYTNAARACNGARATHTCNTCNCAR AARGAYAARATHTTYAARYTNGGNMGNGARYTNGARMGNYTNMGNAGYCAYYTNATHGAR ATHGARGARGGNTAYACNAARGARGCNATHGARGCNGARGARMGNGARAARGARYTNMGN AAYAARYTNGCNGTNGCNGARGARCARYTNYTNACNTCNTCNTCNCAYGTNCARYTNGCN AGYCARGARTCNCARMGNCARATHGARAGYYTNCARGARCARYTNCAYCAYATHGCNTCN CARMGNGAYGCNGCNTAYATGCARGTNGCNACNACNCARGAYCARTGYCARCARTAYGCN GCNTCNYTNAGYAAYYTNCARYTNGTNYTNGARCAYTTYCARAARGARAARGAYTCNGCN ATHGCNYTNGARACNGARAARTAYCAYGAYCARGCNAAYTGYYTNAGYAAYAARGTNAAR GARYTNAARAARGARYTNGARGCNACNMGNGGNGAYYTNACNGARGCNYTNGAYGGNYTN GARGCNGCNGCNMGNYTNAGYGARCARYTNGAYMGNAARGARGARGCNYTNATGGCNYTN AARGARGARGTNCARYTNMGNGARCARACNYTNAARGGNGCNGARGARGARATHGCNMGN YTNAAYTCNAGYAARGARGCNAARGTNGAYAARATGYTNATGCAYAAYATGGTNYTNACN TGGYTNACNTCNCCNGARAARAARMGNCAYGARATHGTNCARYTNATHGGNCAYGTNYTN GAYTTYAGYTCNGAYGAYTTYTCNAARATHGARTCNGCNCAYAGYCARGAYAAYYTNTGG ATHGGNTTYTTYAARMGNTCNGCNTCNAARTCNCCNCARTCNACNCCNAGYAARGGNGAY CARTCNTTYTCNCARYTNTTYGTNAARTTYYTNGARAARGARTCNTCNCCNGCNCCNGCN CCNTTYCARYTNCCNGCNGARGCNATGGCNGCNGARGCNCARCARMGNCAYAARACNGCN TTYAAYCCNTTYATGGCNCCNMGNCAYGTNACNCAYGGNAAYGARGCNTCNGGNYTNTCN TCNGGNTCNGCNTCNCAYYTNYTNYTNCCNCARGAYAAYCCNCAYCCNTCNCCNYTNTTY GCNCCNGTNACNAGYGTNTCNAGYACNGGNGARAGYGCNATHYTNAARGAYGTNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARAGYTTYACNTCNYTNGARGARACNAGYTGGMGNCARGARATGGARATHTAY AAYACNGGNATGYTNAGYCAYGARAAYATHYTNGTNTTYCAYGCNTCNGAYACNATHGGN YTNTCNTCNTGYACNCARAAYATHYTNATHGTNCARTAYCAYCCNAAYGGNTCNYTNTAY GAYTAYYTNCARMGNMGNGAYATHGAYATGGARGARATGYTNATHYTNGCNAGYTCNGCN GCNGCNGGNATHAGYCAYYTNCAYTAYGARATHAARCARGGNACNGGNACNCAYGARAAR CCNTCNATHGCNCAYMGNGAYATHAARTCNAARAAYATHYTNGTNAARAAYAGYGGNGAR TGYTGYATHGGNGAYYTNGGNCAYGCNATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGYTNTTYAAYYTNGARGAYTGGAARCARGGNATGGAYYTNYTNTGYGARGAYYTNAAY MGNAARYTNGTNTTYMGNAARCAYTTYGAYTGYYTNTCNMGNTTYGCNCCNMGNATHTCN GGNTGYATHYTNATHMGNACNCARATGTTYAARAARGCNATHYTNGAYGCNGGNATGGCN ACNCAYAARACNYTNCAYGAYATHACNTGYAAYTTYGCNGARAAYATHGTNAAYTGYYTN GARMGNCCNYTNGGNMGNCARTGYCCNATHCARGTNGTNGAYACNATGGTNACNGCNYTN CAYMGNTTYYTNCCNCCNGCNTGYGCNCCNYTNCCN------------------------ ---------GCNAARGAYGCNAGYGAYGTNACNGTNYTNGARACNGTNATHYTNGARGGN GGNGGNGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CARCARCAYAAYTAYATH CARGCNTCNAGYAGYGCNCCNGAYCCNGAYATHTCNAGYCCNYTNGTNGAYGGNTCNYTN GGNGGNGCNGARTTYATHCCNTCNGAYTTYGAYYTNYTNGGNGGNYTNTGYTCNGTNGAR CARYTNGARYTNGGNMGNATHYTNAAYGAYAGYGAYYTNATHGARYTNCARCCNTCNYTN GGNACNGARGGNYTNAAYCARTCNGGNATGGTNTCNGGNTAYGAYGGNYTNGARACNGAY GGNTCNATGGCNCARGGNTCNGGNGTNAAYTCNTGYCCNACNGGNAARTAYCAYTCNGCN GAYATGGCNCAYACNGGNATHATGTCNGTNCARGAYGARATHTGGMGNAARGARMGNATH AARAARGAYAAYCAYAAYATGATHGARMGNMGNMGNMGNTTYAAYATHAAYGAYMGNATH AARGARYTNGGNGGNYTNYTNCCNAARAAYATGGAYCCNGAYTCNMGNCARAAYAARGGN ACNATHYTNAARGCNTCNGTNGAYTAYATHAARGGNYTNCARGARGARCARMGNMGNATH MGNGCNATGYTNGAYGARAARAARAARGCNGARYTNGAYYTNMGNAARGTNYTNATHMGN YTNAAYCARATGAAYYTNGTNATGAARTCNCAYGGNATHGARTCNGGNAGYYTNGAYGAY YTNGARYTN---TCNTCNAGYGTNGCNACNAGYCCNYTNACNYTNACNCCNTCNTCNCAY GGNAAYCCNATHACNACNCAYCAYAAYATHATHACNAAYAGYAGYCARGTNYTNYTNACN AGYACNYTNATGTCNGAYGAYYTNATGGAYGAR---TCNCCNGTNAGYGGNGAYCCNATG YTNATGTCNGARCCNGTNAGYCCNGARCCNGAYGARGTNGGNTTYCAYTTY--------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGYTNCARGAYMGNATGGAYMGNYTNCARGAYGCNYTNAAYGCN TAYGGNCCNAAYTCNCARCAYTTYYTNAARGAYTCNGTNGCNAGYCCNTGGGARMGNGCN GTNGCNGTNAAYAARGTNCCNTAYTAYATHAAYCAYGAYACNGARACNACNCARTGGGAY CAYCCNCARYTNACNGTNATHATGGAYCARYTNATHGAYATGAAYAARATHMGNTTYGCN GCNTAYMGNACNGGNATGAARYTNMGNTGGYTNCARAARGARYTNCAYYTNCAYACNGTN ACNYTNCARATGGCNATGGARTCNTTYGAYAGYCAYGGNYTNMGNGGNMGNAAYGAYAAR YTNATGGAYGTNGGNGARATHATHGARTGYYTNTCNTCNATGATGGARTCNGCNGCNAGY CARCAYCCNGAYGTNGTNAAYGTNCCNYTNTGYGTNGAYYTNACNYTNAAYTGGATHYTN GAYGTNTAYGAYAGYGTNMGNAGYGGNAARATHMGNGTNYTNTCNTTYAARGTNGCNGTN GTNYTNYTNTGYCARGCNCARYTNGARGAYAARTTYMGNTAYATHTTYMGNYTNATHGCN GAYGCNAAYGCNTTYGCNGAYCARMGNAARATGGGNYTNYTNYTNCAYGAYTGYATGCAR ATHCCNMGNCARYTNGGNGARATHGCNTCNTTYGGNGGNAGYAAYATHGARCCNAGYGTN MGNAGYTGYTTYGARAARGCNAAYAGYMGNCCNGARATHGARGCNTAYCAYTTYYTNGAY TGGYTNAARYTNGARCCNCARTCNATGGTNTGGYTNCCNGTNYTNCAYMGNGTNGCNGCN TCNGARACNTCNAARCAYCARGCNAARTGYAAYGTNTGYAARGAYTTYCCNATHYTNGGN TTYMGNTAYMGNTGYYTNAARTGYTTYAAYTTYGAYGTNTGYCARAAYTGYTTYTTYTCN GGNMGNACNGCNAARAGYCAYAARYTNGCNCAYCCNATGCARGARTAYTGYACNACNACN ACNTCNGGNGARGAYGTNMGNGAYTTYTCNAARGTNTTYAARAAYAARTTYAARTCNAAR MGNCAYTTYAARAARCAYCCNMGNMGNGGNTAYYTNCCNGTNGARTCNCAYYTNGARGGN GAYAGYYTNGARAGYCCNAAYCCNTCNCCNCARCAYAGYATHTCNCARGAYATGCAYTCN MGNYTNGARATGYTNACNAGYMGNATHGCNGARGTNGARCARMGNCARGGNGGNTCNGCN GAYYTN------------------------------------------GARGAYGARCAY CAYYTNATHGCNCARTAYTGYTCNAGYYTNAAYGGNGARCCNAAYTCNCAYGCNYTNAAR AGYCCNATGCARATHATGATGGCNGTNGAYGCNGARCARMGNCAYGARYTNGARTCNATG ATHCARGAYYTNGARGAYGARAAYAARACNYTNCARGCNGARTAYGAYMGNYTNCARATG GCNGCNCAYGARMGNGCNTCNGAYMGNYTNMGNYTNGGNTCNGGNGARGGNGAYAGYGGN AGYCARGGNCARCCNAGYMGNGAYGARGARATGYTNGARGARGCNAARYTNYTNMGNCAY CAYAARGGNMGNYTNGARGCNMGNATGMGNGTNYTNGARGAYCAYAAYTCNCARYTNGAR TCNCARYTNACNMGNYTNMGNCARYTNYTNGARCARGCNCCNGGNGAYAARAGYCAYATH TCNYTNGAYTCNTCN---MGNACNACNCCNYTNACNACNCCNTCNTCNTCNCARAGYTCN TTYCAYATHGGNTCNAAYAGYTTYMGNATGGCNCCNCARATGGARTCNACNCCNCARTCN AAYGGNCAYAGYGCNATGAGYYTNACNGAYGAYCCNGAYYTNAGYGGNATHATHGGNAAR GTNAGYAGYCCNCCNCARTAYAAYGCNATHAARACNAARCCNGGNAAYGTNAGYGAYYTN TTYCAYATHGCNGGNGARYTNGGNGARGCNGTNGGNTCNYTNGTNACNGTNATGACNGAY GARGAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MGN GCNYTNGAYTAYYTNMGNYTNTGGAARAARAAYTTYAARTCNTGGAARTTYAGYAARYTN TAYCARGCNMGNYTNATHAARATHYTNTAY---GARCCNGTNGTNACNGARGARGAYTTY GARATHTGYYTNCARTAYTTYGARAARTGYCARGGNAARGCNMGNGARCARYTNAARGCN GAYGCNATGGAYATHATHAAYGARGAYGARGAY------------YTNGCNTAYATHGAR GGNTGGAARYTNATHAAYATHGCNAAYGARYTNTTYGGNTTYACNGGNTGGTCNCAYTCN GTNAGYAAYCARACNGTNGAYTTYGTNGAYCAYATHAAYGGNAARTAYTAYGTNGGNGTN TCNGCNAAYGTNMGNGTNACNYTNAARAGYGGNGTNTAYCAYGARGAYGTNGGNTAYGGN GTNAGYGARGGNATGMGNTCNAARGCNYTNTCNYTNGARAARGCNMGNAARGARGCNGCN ACNGAYGGNYTNAARMGNGCNYTNAARAGYTTYGGNAAYAGYYTNGGNAAYTGYYTNTCN GAYAARGAYTAYYTNAARTGYATHAAYAARGCNCCNAARCARCCNCCNCCNACNTAYAAY GTNGARGAYATGAARMGNGGNACNGARGAYACNYTNGTNTTYAARGCNMGN--------- ------------------TAYYTNCCNTGYGAYGAYTTYATGAARTTYCARGAYTCNYTN AARMGNYTNMGNYTNATGGAYGAYMGNATHATHCAYGCNYTNAAYAARAAYYTNCCNACN CARTCNTTYMGNGGNAGYGTNGAYGTNGCNTCNAAYTGYMGNCAYATHTAYGAYGAYATH CARACNTCNTAYAGYCAYMGNGARAARTCNATHCARCAYTGYATHMGNYTNGTNAGYGAR GAYGTNAARAARYTNAAYGARAARMGNCARCARGAYCCNGAYAGYTTYGAYGTNATHAAR TCNYTNMGNMGNGARCARACNAARYTNMGNYTNATGCARCARGARATGAAYGTNGARGAR GTNGTNAARGAYMGNACNYTNAARGTN------------ATGGTNMGNTCN--------- ---YTNYTNAGYMGNCARCCNMGNYTNGAYGGNYTNTGYCAYGGNCAYGGNCCNCAYTCN CAYGTNTTYGAYGGNAARTTYATGCCNCARGTNACNGGNMGN---GAYTGGACNCAYGAR AARGCNTCNYTNGCNATGTTYGAYTAYATGATHGARGARCAYGGNTTYATGCARCCNGGN GGNGTNYTNTTYAARCAYMGNYTNAGYGARAARGAYATHGTNTTYATHAARGARYTNATH AAYGGNCCNYTNGGNAAYACNGARCAYGAYTGGCCNTAYYTNGGNMGNGARAARGARAAR GCNTTYYTNTAYCARATHGTNTCNAAYAARYTNACNGGNATHGAYGTNGAYAARTGGGAY TAYTTYGCNMGNGAYTGYCAYCAYYTNGGNYTNGTNAAYAAYTTYGAYCAYGARMGNTTY ATHAARTTYGTNMGNGTNYTNGAYGTNAGYGGNMGNCCNCARGTNTGYTCNMGNGAYAAR GARATHGGNAAYYTNTAYCARATGTTYCAYACNMGNTAYATHYTNCAYMGNACNGCNTAY CARCAYAARGCNGTNTGYGCNTGYGARYTNATGGCNGTNGAYGCNYTNYTNAARGCNAAY GAYGTNYTNCARATHTCNGCNGTN------------MGNYTNTCNGAYAGYGCNACNAAY ATGTCNGCNTAYATGTAYGTNACNGAYGAYATHYTNTGGGARATHTAYAARTCNMGNGAY GARAARYTNGGNCCNGCNAARGAYATHATHAARMGNYTNTTYMGNMGNGAYYTNTAYMGN TGYYTNGAYGAR---MGNAGYATHACNCCNAARYTNAARGARYTNCCNYTNAAYGARYTN MGNGAYCARYTNCARYTNTCNGARAGYACNGARAARCCNCCNGARATHCCNGARTTYGAR TTYMGNTTYCARATHGTNTCNATGGAYTAYGGNAARAARGGNAARGAYCCNYTNAARGCN ATGMGNTAYTAYTCNAARTTYGAYCCNGAYACNCCNAARGARGCNACNAARGARGCNGGN YTNYTNCCNCCNMGNTTYACNGAYACNYTNATHMGNATHTAYAGY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARTTYYTNTCNTAYACNGGNACN CAYGGNGARAAYAARGARTTYCARAARGAYGARGGNTGGAARACNYTNGAYGARGARCCN GTNTTYGAYGARGARGAYTAYYTNAAYTAYATHAAYCARCAYCAYCCNCARCCNGGNGTN GTNGAYCCNCCNGAYCCNAAYYTNCAYTTYCARCCNGARAGYCAYCAYCARCAR------ ---CARCARCARCARCARAAYCARCARCARACNAGYMGNATHTCNAGYATHAARMGNAAR ATHGARGAYYTNAARMGNGGNGCNAARCARMGNAARYTNGAYGGNATHAAYAGYAAYAGY CCNGCNACNGARAAYAAYATHGCNGTNAAYMGNYTNCCNGAYGARMGNYTNMGNMGNCAY GGNGTNAARATHYTNTCNGCNGARGARMGNGCNAARAAYTCNGTNYTNAAYGCNGARGCN GTNCAYAAYTAYTGYAAYAARYTNTTYYTNTTYAARACNGTNGTNGTNAARAARTAYMGN ACNTGGMGNGARMGNMGNAARCAYYTNATGGGNAARAAYMGNACNAGYMGNCCNGARYTN CCNTCNGAYACNAARYTNATHACNTGYCCNATH---AARAAYTCNCARGGNGCNGGNATG GCNGGNAARAARAARGARTTYGTNYTNAAYCCNTCNGGNAARTCNTAYYTNTGYATHYTN CAYGARTAYATGCARMGNACNYTNAARATGCARCCNACNTAYGTNTTYAARGARYTNGAR AAYCCNAARACNCCNTAYGGNGCNACNGTNAARATHAAYAAYATHGARTAYGGNACNGGN YTNGCNTCNTCNAARAARACNGCNAARCARGARGCNGCNAARGARACNYTNAARATHYTN ATHCCNGAYYTNTCNTCNAARATHTCNGAYCARGARYTNAARAAYACNGTNTCNGAYYTN TCNTTYTTYGAYGARATHCARGTNGARGAYCCNMGNGTNCAYGARYTNGGNAAYAARGTN GGNCARCCNAGYCCNTTYCARYTNYTNMGNGARTGYYTNMGNMGNAAYTTYGGNATGGGN ACNCCNCARTGYTCNGTNAAYACNACNGCNYTNAARAAYCARAARTGYGARTTYACNYTN AGYGTNGGNAARCAYTCNGCNACNATHGTNGCNAARAAYAARMGNGAYGGNAARCARYTN GCNGCNCARGCNATHYTNGCNAARYTNCAYCCNCAYGTNCCNAGYTGGGGNTCNYTNYTN MGNYTNTAYGCNACNAAYGTNGARAARCCNATGGARAARGTNGARGARATGAAYGARATH AARACNCAYGTNCCNAAYAARGCNGTNYTNGARAARYTNMGNAARGARATGMGNAARYTN CAYAARCARAARGARGCNATHCARTCNAARGGNAARATGYTNATHTCNACNAARGAYYTN CCNAGYAARATGTCNTGYGTNGAYYTNATGGTNGCNTTYGGNYTNCAYYTNGGNGCNTGY TCNGCNTGYYTNGCNGTNCAYMGNGAYGGNAARACNGARGTNATHGCNAAYGAYYTNGGN GAYMGNGTNACNCCNACNGTNGTNGCNTTYACNGAYCAYGAYATHTCNGTNGGNGCNGGN GCNAARCARGGNGCNGTNMGNAAYGCNGCNAAYACNATHGCNCAYGTNAARCAYATHGTN GGNAGYGARAGYGARGAYGCNCCNGTNAARGARTAYATHCARAAYCAYCARGTNGAYGTN AGYAGYCARAAYGGNTCNGTNATHTTYAAYGTNGARCAYCARGGNAARAARGTNCARTAY ACNCCNAGYMGNATHYTNGARYTNATHTAYAAYAARATGYTNGARACNGCNCARAGYCAR GTNGGNAGYGGNACNAARGAYGCNGTNYTNGCNGTNCCNTCNGAYTTYACNCARCARCAR MGNAAYATHYTNAGYGARGCNGCNTCNAARGCNGGNTTYAARGTNYTNMGNYTNATHAAY GARCCNTCNTCNGCNATGYTNGCNTTYGAYGTNGGNCARTTYGAYGARTCNGARCARGAR TTYAARACNYTNGTNTAYMGNTTYGGNGGNACNTCNCAYGAYGCNACNATHATHAGYGTN CARCAYGGNATGTAYTGYATHAARACNAARGCNTCNGAYAAYCARTTYGGNGGNGAYAAR YTNACNGARGTNYTNCARGGNTTYYTNGCNTCNGARTGYAGYMGNCARYTNMGNTGYGAY GTNACNGARAGYAARMGNTCNATGAGYAARYTNAARYTNGCNGCNGARMGNTGYAARCAY TCNYTNAGYTCNYTNTCNAAYGCNCARTGYAGYGTNGAYTCNATHTTYGAYGGNYTNGAY TTYTCNTAYAAYGTNTCNMGNGCNMGNTTYGARAGYYTNTGYATGCCNMGNATGTCNCAR TGYACNCARYTNGTNCARCARGTNYTNAAYAGYGCNGGNTGYACNAARGARGAYATHTCN AARGTNATHYTNTGYGGNGGNGGNGCNAARTCNCCNATHGTNAARAARGTNYTNACNGAY TTYYTNCCNTCNTCNGCNYTNYTNAAYTCNATGGCNGARGAYGARATHATHGCNATHGGN GCNGCNAARGARGCNGCNYTNYTNGARGGNGAYGAYGAYGAYGAYGTNGARATHCARGAR CARMGNTCNAAYGCNTTYAARTCNYTNTCNAARGCNATHTGYYTNMGNGTNAAYTCNCCN GARYTNAAYGTNATHYTNTCNCARAAYTGYYTNATHCCNGCNMGNMGNCARCAYACNYTN ACNYTNCCNACNACNCARACNAGYGTNAARYTNGARATHYTNCARGCNTCNGARCCNATH ACNTCNGAYACNGARGCNCARYTNYTNGCNAARATHGTNYTNMGNGAYYTNCCNCCNGGN TCNAGYATHAARTCNAGYTTYCAYYTNACNMGNCCNACNCCNCCNACNTTYCCNGAYGCN TTYAGYATHTCNTTYCARGARATHGARATGYTNGTNGGN------------------CAY GTNYTNAGYACNAAYAAYGGNTCNTGGTAYTTYGAYTTYGCNAAYMGNMGNGCNMGNTTY GAYCAYAAYMGNGGNCARACNAAYAAYTTYTGYGAYTAYCARAAYYTNAGYCCNAARGAY CCNAARGCNGGNTGYCARYTNTTYTTYACNCCNACNGARGAYYTNATHGTNTTYTAYCCN GTNGTNCARAAYTGYTGYMGNYTNTGYGGNAARAAYGARGGNTGYACNATHYTNAARCCN AAYTGGYTNCARCARGAYTCNAARYTNATHTCNGTNGARGARATHAAYGGNGTNAARTGY TAYGGNTGGGCNAARCARGGNGCNGTNGCNGCNGCNGAYACNTGGTTYGCNACNGCNGAY GGNGTNCCNTGYMGNTAYCAYGARGTNGTNGTNCAYATHGAYCAYAAYYTNACNTTYGTN CCNCARACNTTYAARATHGGNCCNCARGAYCCNGCNYTNTTYCARGTNCCNTCNTGGTGY AAYAARACNTGYCCNCAYCCNTAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GAYGAYATGTTYAARGTNAARGAYCCNYTNCCNTTYCCNYTNTAYCCNYTN CAYGGNGGNAARACNGAYTCNYTNCAYGTNCCNTGYGGNAAYGTNCCNYTNTTYYTNTAY TGGGGNAARMGNCCNMGNCCNYTNAAYTTYAAYMGNCARTGYGGNACNYTNGGNATHTAY GAYATHGTNTAYGAYATHACNGGNTAYGAYATGACNACNACNTCNAARGARGAYYTNCAY AARGARATGGTNGAYGARGCNYTNTCNGTNGCNGCNTTYACNCCNGAYCCNGAY------ ------------------AARGARACNGTNYTNAARTCNGARTAYGAYAARYTNGTNGAR AARCAYCARGARGARATGATHTAYYTNCARGARGARTAYGARAARMGNYTNCARGARYTN GTNCARAAYYTNCARACNATGCARGCNGARAAYGARCARGTNCCNCARATGATHTCNCAR CARYTNGCNCARCARMGNCCNYTNTCNCARGCNTCNMGNGTNAGYACNACNCCNGGNGCN ATGACNCCNATHACNTCNAARMGNTCNGARMGNTCNGAYCCNTCNTTYTAYGARAGYATG GCNYTNCCNCARACNGGNCARAGYATGMGNACNTTYAGYMGNGAYAARACNAGYGTNGGN GARATGGARMGNGARAARAGYATGATGTCNCARAGYACNGCNAGYACNMGNYTNAARCCN YTNCCNCAYMGNAAYACNMGNCARACNAARAAYTTYMGNATHGGNAARCCNYTNCCNAAR TGGGGNGARACNYTNCCNCARGAYTTYTTYGAYMGNYTNMGNYTNTGGGARGARGARAAR AARCARCAYAARCARGARYTNAAYGARAARACNYTNAARGAYATHAARGAYAAYYTNGAR AARAARYTNGCNGGNCARCAYAARYTNAGYAARMGNGARGARCARATHTAYGAYGCNYTN AARGAYGTNAGYYTNCCNGCNYTNTTYATGCCNTAYAARACNGGNAAYATHTAYAAYCCN MGNGCNCAYCAYTAYTTYCAYCCNACNGGNTCNTCNGAYGTNMGNYTNACNCARCCNCCN TCNGTNTTYACNYTNCCNCCNYTNCCNAAYAGYAARYTNTCNGTNGTNAAYYTNTTYGAR YTNAGYAARAAYTTYMGNAAYMGNGGNCCNGCNTGGYTNGTNGARMGNTAYATHCARCAR CARCARCCNTCNCAYGARGAYTAYCCNCARACNCCNGCNCCNACNTCNGCNATHCCNCAR GTNACNACNACNTCNGGNCARAGYCCNATHGAYGARAAYGCNGCNACNCCNACNAGYCAR MGNAGYYTNCARCCNGARGTNGAR------------------------------------ ------------------------------------------------------------ ------------------------------------GGNCCNACNTCNTGYACNATHMGN ATHACNTCNGARTCNGGNCAYCARGGNGTNCARYTNCARATHGTNATHATHTCNGTNGAY ATHCARGAYTGYMGNACNCARYTNTCNATHTAYGAYGGNCARGAYACNCARAARATHGGN TCNTTYGAYTGYCAYAGYAGYAARAAYGCNAAYMGNATGCAYYTNGTNACNAGYGGNGAY ACNGTNTCNTTYATHATGACNMGNAAYAAYCCNGAYAGYCAYAAYTTYGAYATHGARATH MGNATHAARCCNATHMGNGGNGGNGTNGAYCCNGAYTAYGAYAARAAYTAY--------- TTYAGYTTYCARAARTTYGARCARGARGCNATHGTNGGNATGATHGGNGGNTTYTAYGGN YTNATHATHATHATHTGYATHGCNGTN---GTNTGYTAYTTYAAYATHMGNTAYGGNYTN AAYAARAAYTGGGARACNCAYCARYTNGCNACNATGAARACNGAYACNAGYTTYGAYGGN MGNAGYCARGTNTCNCAR---------GCNCCNTGGTCNGTNGCNACNCARAAYAARGGN CCNGTNAGYGCNTAYGCNMGNTCNTAYACNGAYCCNTAYTCNMGNAARGGNGCNCAYGCN MGNAGYGARGAYGGNTCNAGYGTNGTNTAYGAYCAYGAYGARAARTTYCARCARMGNAAY YTNATGAAYGAYGARMGNGAYMGNCAYMGN---GGNMGNGAYMGNATGGCNTCNCARAAY AAYACNTAYGAYGAYGAYGARGAYCCNGAYAAYTTYAARGARAARGTNATHACNCCNMGN GTNAARCCNTCNGGNTCNMGNCARGAYMGNCCNCCNTCNTTYGARGARGCNACNMGNAGY MGNTCNATHGARMGNTCNTCNGARGARGARGARACNGARGARGARTCNAGYGAYAAYGAY TCNACNMGNAARMGNYTNACNACNTCNTCNGARGGNGAYGARGAYAGYGAYGAYGAYACN GARAGYGARTCNGARTCNGARTCNGARAAYAGYTAYGCNAGYAGYTCNMGNMGNGGNYTN GGNGCNMGNGCNGCNMGNMGNCCNAARAARACNMGNAARGARAARTCNMGNYTNAARTCN AARGCNGGNMGNMGNMGNCARTCNTCNACNGAYGAYGCNTCNTCNCARMGNCAYCCNCAY CCNTCNCAYCARGCNCCNATGCCNGGNATGGCNATGCCNTAYGGNCCNTAYCCNGCNCCN CCNGGNGGNCARTTYGTNCCNGTNATGGCNGGNCAYCCNCCNCCNTTYCARCCNGTNCCN ATGATGCCNCCNAGYTAYGCNCCNCCNCARTAYCCNATGGAYTCNCCNAAYACNGCNTCN CARGGN---ATGGTNCARCCNACNGAYCCNCCNGTNTAYTCNTAYYTNGTNMGNMGNGGN TAYACNCCNATGGAYCARCAYAAYTCNCCNGCNGGNAGYGTNTCNAGYGGNCARMGNGGN CCNCCNGCNYTNMGNGARGARCCNGAYACNCCNYTNCARAGYGGNGTNGARTAYATGMGN MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------YTNAAYTGYCCNMGNTGYAARCARAARACNCARYTNCCNTCNCARGGNGTNACN AGYYTNCARTCNGAYYTNGTNYTNGAYGAYATHYTNCARAARGAYTCNGARGARATHAAR CARATHGGNTGYACNAGYTGYAARGCNGARGAYAARGCNGTNGCNMGNTGYAARACNTGY GARAAYYTNYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TCNGAYGARATGYTNAARGCNATHTCNAGYAAR GARAAYMGNTTYAARMGNACNGCNGARGCNYTNCAYAARTCNGGNYTNTGGGAYATHGCN ATGAARACNGGNCAYYTNATHAARMGNAAYCARGARYTNCARAARGARYTNGARCAYTTY AARATGGAYGCNYTNAAYTTYYTNAARTCNGTNATHAARAAYCCNGARAAYMGNGAYTTY ATHAARAGYGTNYTNAAYAGYGCNYTNTGYGCNGGNGCNGGNGGNTCNAARAARTCNGTN ATGACNGTNGTNGTNTCNGCNGCN------------------------------------ ------------------------------------------------------------ ------------------------------------CCNTCNGCNYTNYTNACNYTNATH CARGARAARGGNYTNAARYTNGGNGGNGTNGTNGAYYTNACNTAYACNACNAARTAYTAY GAYGCNCARTTYTTYACNACNTGYGGNGTNGGNTAYAARAARGTNTTYACNGCNGGNCAY GTNATHCCNAAYGAYAARACNTTYGARCARTTYACNAARGCNATHAARTCNYTNGARAAR GARGGNGARGTNATHTGYGTNCAYTGYACNCAYGGNYTNAAYMGNTCNGGNTAYATGATH TGYMGNTAYATGATHGARGTNYTNAAYATHGARCCNCARATHGCNATHMGNYTNTTYGAR CARGCNMGN--------------------------------------------------- ------------------------------------ATGGGNTAYGTNACNGTNTGGGAR YTNGTNYTNTGYTAYYTNGTNGTNGCNTGYGTNGCNAAYAAYCCNCCNTCNYTNTCNGGN AARGTNGTNTCNMGNGTNATHGCNAARGTNGGNAARAAYTCNMGNYTNYTNTGYCCNGCN AAYTCNGAYCCNTCNYTNACNCARTGGAARAARAAYGGNCARGCNYTNAAYCCNGGNTGG GARMGNTTYAARGTNTCNCCNAARGGNCAYYTNMGNATHMGNGAYGTNCARYTNYTNGAY GCNGGNYTNTAYACNTGYGTNGCNACNAAYGGNTAYGGNAGYATGAAYATHAAYTAYACN GTNATHGTNYTNGAYGARGARAAYCARGTNTTYCARGARGCNGAYAARYTNATHAARCAR TCNCCNGGNGARGAYATHTAYMGNGARGGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AGYTCNAGYGGNAGYCCNACNCCNAGYGAYAGY AGYAGYCARAAYGCNGCNATHAGYCARCARGCNYTNAAYGCNGCNATGCCNATGAARAAY GARGARACNTCNAARYTNACNGCNTCNYTNTCNAAYTAYTAYAAYGARTCNYTNATHGGN CAYGTNYTNGGNTGGCARGCNGAYACNYTNGARAARCARGCNACNAARYTNTGGGARGAR ACNATGGTNAAYGGNAGYYTNCARTGYAGYCARATHTCNGTNCARYTNAARAARGCNMGN TCNYTNGTNMGNATHGCNGARATHCARTCNACNYTNCAYGARCARMGNATHATGTCNTCN GAYCARCARMGNCARTCNYTNTTYGTNTCNGAYACNAARCARTAYTAYMGNATHACNTCN GARYTNTGGAAYGGNGARAGYATGAGYMGNTTYACNMGNMGNGARYTNGAYYTNTAYMGN CARTTYTCNTCNGAYYTNCCNGTNATGAGYATGGTNYTNATHATHGCNTTYGCNCCNGGN GGNATHTTYATHTTYGCNGTNGCNTAYYTNTTYCCNMGNTAYYTNYTNTCNCAYCAYTTY TGGACNMGNGARCARAARGARAARTTYMGNMGNYTNGARATG------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CAYGARCAYGAYGAYGAYGAYCAY TGYCAYYTNTCNGCNAARTAYACNGARTAYATHAARATHCAYYTNGARGAYYTNCARTCN AARTGYAAYCAYYTNACNGTNTGYATHAAYAARYTNYTNTCNCARCARAGYCCNATHTCN GTNYTNAARGGNGAYAAYYTNGARYTNAARAARATHTGYGARYTNATHAAYATHAARAAY AAYACNGCN---TCNATGYTNGAYGGNAARTGYTCNYTNCAYGARMGNATGGAYATHATG GTNGAYGTNGARAAYCAYYTNAARGAYAARATGGARAARAARGAYAAYTGGGARAGYGTN GCNGTNTGYYTNGARAAYAAYTAYGGNGAYAAYGARMGNACNACNTAYATHGGNGAYATH TGYGGNYTNGTNGARAGYMGNGGNCARATHTGY---TCNTAYAAYACNCAYAARCARGTN GARAARTTYATHAAYGARCARATHGAYCAYYTNCARTGYACNTGYAARGCNYTNACNMGN GAYATHGAYCAYCAYCAYAGYGARYTNTCNATHGCNGCNATHGCNGGNATHGGNGTNGGN GCNTTYYTNYTNTGYYTNATHTTYGGNYTNATHTTYTTYTGYTAY---ATHMGNAARCAR AARAARMGNMGNAARAARAARGGNCCNAAYGTNATHTAYYTNCCNGCNGCNAAYGCNGAY AAYTGYCCNGTNTAYCARGARATHTTYGAYCARMGNTCNCCNCCNYTNAGY--------- CCNCCNACNYTNCCNAGYMGNTAYATGTCNMGNCCNCCNGGNAGYCCN------------ ------GAYGAYACNGARTAYYTNGARCCNGTNCARGCNCARGCNGCNGGNAGYTAYMGN AARGCNCCNGCNCCNYTNCARMGNYTNGTNAAYAAYCCNGGNTAY------GARGTNGAR GCNCCNCCNGARTAYAGYGARACNGAYCARACNTAYGAR---------------GAYGCN GTNYTNATGGAYGCNGARGCNGCNAAYACNTAYTTYGARCCNATHGTNACNCCNAARACN GARAARACNGAYAAYAAYAAYGARGAYGAYCAYACNAGYGARTAYCARGTNYTNCARGAY ATHGAYAARGAYAARAARYTNGGNCCNYTNCCNGCNCARMGNGTNAARAARGARGAYMGN GTNACNGARTCNGARTAYTTYGARYTNGARATGYTNGARGARGGNAGYGTNACNATGGAR AARAARYTNATHAAYMGNCARTCNCCNGCNCCNGGNCARTGYAARAAY---GGNGCNACN AGYGARMGNAARTCNGAYTTYACNCCNAAYMGNMGNGGNCAYAGYMGN---MGNTCNGGN TCNGGNGGNGGNGCNAARACNCARGAYGTNGGNCARACNCCNMGNCCNAGYCCNATHAAY AARTGGGAYMGNTCNGTNGGNAAYMGNMGNCARMGNCARMGNAGYGGNTAYGAYTAYMGN CARMGNGARGARGTNGARGARCAYGAYGAYGTNTTYGAYGTNYTNAGYACNGGNTCNMGN AARGGNAAYYTNAAYCAYYTNYTNAAYTTYAARTTYYTNCCNMGNCAYCARAGYCARGTN GAYGAYCAYMGNTGGCARGAYMGNMGNCAYTAYAAYTCNCARGGNMGNGGNGGNTTYMGN AARMGNAARMGNTAYAARAARGARCARTTYYTNCARGCNAGYTGYCARTTYGTNGTNMGN GAYACNGGNGAYTAYGCNGARCARGCNATHAAYTCNGAYGCNYTNGTNGAYTGGAAYATG ATHGARYTNGTNMGNAGYTTYTGYACNGARCCNGTNAAYTGYCCNATHTGYYTNGARATG CCNACNGCNGGNAARATHACNAARTGYGGNCAYACNTAYTGYTGGGCNTGYATHYTNCAY TAYYTNAARYTNGGNGARGGNGARGCNMGNAARTGYCCNATHTGYTAYGARACNGTNGAY GTNGARGAYYTNAARAGYGTNCARTGGATHGAYGTNCCNAAYTTYAARGTNGGNGAYACN ATHGAYATGMGNYTNATGAARAARGCNAARGGNAGYGTNATHAGYATGCCNAARGAYCAR TGGGARGAYMGNYTNGGNAARCCNATGAAYGTNCARGAYGGNGTNAAYACNGARTTYATG AARYTNYTNGTNGCNTCNTCNGAYCARATHCARACNGARGTNATHGARACNGARMGNGCN TCNYTNACNGTNCARYTNGARGARGCNGARGARTCNGARACNTGYTTYATHCARATGGCN YTNCARTCNYTNGARGCNMGNGARAARTCNYTNCARGTNTTYCARCARACNGCNGARACN AAR---------------------------------------------GAYAARGTNCAR ATHCCNGGNYTNTGGTTYAAYGAYGCNAAYAARGCNAARACNTTYGAYCARAARAAYGAY GAYATHTCNGARTCNACNTCNYTNACNAAY---------------------GARACNACN GARATGACNGGNAARGAYATGGCN------------------------------------ ------------------------------------------------------------ ---------------------------------------------------YTNACNCCN AGYGAYCCNCARTAYTCNMGNCARMGNCAYGAYAGYGARTGYTCNYTNCCNTTYGGNTCN CCNCCNTGYCCNTTYCCNYTNGTNCCNGAYCARGARGTNAAYCAYGTNCCNYTNACNYTN GARGARACNGCNGAYCAYYTNGARYTNCCN---------ATHGAYATHCCNCARACNATG GAYAARCARCARCCNAARATGTCNAARGAYAAYTAYNNNTTYTAYCARGCNTCNACNGGN CARCARATHTAYYTNAAYTCNYTNAAYGCNCARTGYATGGCNMGNGARTAYGGNTCNYTN GARGARAGYCCNAARGAYYTNAARGGNACNATHGTNGCNATHGARMGNATHTTYATGACN GARGAYGTNMGNAARMGNYTNMGNTAYYTNGAYCAYATHCCNYTNACNTGYGARGTNCAY ATHGTNGARYTNAARYTNAARCCNCCNGTNGTNAGYAARGARACNYTNAARTTYTTYGAR GCNGCNTTYGAYAARAARMGNAARCARMGNCARCARAARGARMGNGARGAYAARMGNMGN GCNAARAARATHGARATGGARCAYAARAARAGYTTYGGNATHTAYCCNGARGTNCARATH CCNYTNGAYAGYYTNGARCARTTYCCNTCNCAYYTNTCNGCNAGY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATHACNYTNYTNGAYYTN CCNTGGGARCARGTNYTNTGYMGNAAYGTNYTNCCNTAYYTNACNATHCCNCARYTNTTY MGNYTNMGNACNGTNAGYCAYAGYTGYYTNTGYYTNGTNGAYACNTAYTTYAGYYTNCAR TTYCAYYTNAAYATHAGYCAYYTNGGNAARAARYTNACNTCNAARGCNTTYTCNYTNATG ACNMGNGAYAGYMGNTGYYTNAARACNYTNTTYYTNMGNGGNGCNAARTAYGGNYTNAAY AAYGARGTNTTYYTNCCNGTNYTNTCNAGYAAYTCNMGNYTNGARAARATHGAYATHAGY GGNTGYACNTCNYTNTCNGGNTGYGTNYTNTAYGCNATHGGNGTNAAYTGYCCNAARYTN AARCARYTNATHYTNMGNGAYTGYGTNACNTTYATGGARGARAAYTTYYTNTCNTTYYTN TGYGTNAARCAR------CCNGTNGARTAYYTNGAYGTNTCNGGNTGYTGGAAYYTNGGN GAYGAYYTNGTNATHAARYTNGTNCARMGNTGYCCNAAYATHAARCAYYTNYTNYTNGGN AAYYTNTAYGGNYTNACNGAYMGNACNGTNTGYACNATHTCNCAYTCNTGYCCNGAYYTN ATHTCNYTNAGYATHGTNGGNTGYTGGMGNATHACNGAYCAYTCNATHAGYYTNATHGCN GCNTAYTGYCARAGYYTNAARTTYYTNGAYGTNAARGARTGYMGNGAYATHACNGARGAR AGYYTNGGNCCNYTNMGNAARMGNCARGTNAARATHGAYAARCCNGGNCCNCCNCCNTCN TAYYTNAAYMGNYTNGARTTYYTNAAYAARGCNCAYAARATHAAYGTNATGYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TAYTGYTTYGGNGAYAARGTNACNATHGCNGAYATHTGYYTNYTNCCN CARGTNGCNAGYGCNGTN---MGNTTYAAYGTNGAYATGTCNMGNTTYCCNACNATHTGY MGNGTNAAYAARGCNYTNGARGARYTNCCNGCNTTYAARGTNGCNGAYGCNMGNMGNCAR CCNGAYACNCCNGARGARATGAARATHGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGTCNGAYAARYTNACNACNMGNGTNATHCARGTNACNAAY ATHGCNCCNAGYTGYTCNAARGARCARYTNMGNACNYTNTTYGGNTAYYTNGGNMGNATH AARGARYTNGARATGTAYCCNCCNGAYGGNGCNGAR---GGNGTNGTNACNGCNMGNGTN GCNTAYATHGARTTYGARGAYTCNGTNACNACNGGNGTNGCNYTNCAYYTNAGYAGYACN GTNTTYATHGAYMGNGCNATHATGATHGTNCCNGTNATGGAYGGNAARATHCCNGAYGAR AGYTCNGCNYTNCARYTNACNCCNTCNGCNGTNGCNGGNATGYTNCCNGGNCARCCNACN TGGCCNGCNAAYGTNGTNTCNCARGTNACNGGNYTNGGNGCNAAYCARATHATHATGACN AAYGAYCCNMGNYTNACNTCNYTNGGNYTNCCNCARTAYCCNCCNYTNCCNGCNACNACN GAYCCNAGYAARATHGARGARATHMGNMGNACNGTNTTYATHTCNGAYYTNGAYGCNAAR GTNACNCCNGARATGYTNYTNTCNTTYTTYTCNCARACNGGNGARATHAARTAYATHMGN ATGGCNGGNGAYGARAGYGCNCCNACNMGNAGYGCNTAYATHGARTTYACNGAYCARMGN TGYATHGCNCARGCNYTNAGYTAYAAYAAYGTNGTNTTYCARGGNMGNACNGTNAGYGTN AARCAYGCNACNACNAGYATHGTNAARCCNACNCCNMGNTCNGARGCNTCNCARMGNGAR ATHGAYGAYGCNATGAARAARGTNAARGARGCNTCNAARYTNATHTCNGCNGCNGCNAAY AGYGAYMGNGAYAGYTCNMGNTCNCCNACNMGNAARMGNTCNMGNTCNAARGTNMGNAGY MGNTCNMGNTCNMGNTCNMGN---MGNMGNTCNMGNTCNMGNTCN---CCNMGNMGNMGN MGNMGNAGYGGNTCNMGNACNMGNMGNMGNTCNMGNTCNMGNMGNMGNTCNCCNAARMGN TCNMGNTCNCCNATGMGNMGNMGNMGNTCNMGNTCNMGNGGNMGNGTNCCNCCNCCNGCN CCNCCNGTN------------TCNMGNGARMGNMGNMGNTCNMGNACNMGNTCNCCNGTN MGNMGNAARMGNTCNMGNTCNMGNTCNAARTCNMGNCCNMGNMGNTCNMGNACNCCNCCN AARTCNTAYAGYMGNGGNMGNMGNTCNCAYTCNMGNAAYMGNMGNAGYMGNTCNMGNGAY MGNMGNGARAARAARGARMGNAARAARAGYMGNTCNATGTCNCCNCCNACNYTNATHMGN GARGGNTCNGCNTCNYTNGARGARGARMGNGAYAARTCNCCNTCNAARGGNAAYGGNMGN TCNCCNAGYCCNCCNAARACNAARAARMGNAGYCCNACNCCNAARAARMGNAGYMGNTCN MGNTCNCCNAGYMGNMGN---AARAARMGNMGNCAYTCNMGNTCNACNTCN---MGNAAR MGNTCNMGNTCNMGNAGYGGNTCNMGNTAYMGNGCNMGNMGNGAYMGNAARMGNAGYMGN AGYMGNGAYMGNAARCAYGAY---AGYAARAARAARAGYATHMGNGAYAARGARGAYMGN AARAARGAR------AGYAGYTCNAARATHAARMGNGAYTAYGAYGARGARGARAARGGN TTYGCNAGYGAYMGNAGYGAYGARMGNGAY---AAYAAYAGYGARGGNGTNMGNTCNMGN GCNGAYTCNCCNAAYCARCCNCCNYTNYTNGARAARGAYACNGAYAAYCARCCNGTNGAY ATGGAYATGAGYGAYYTNATHMGNACNTTYCARMGNGAYCARAARGAYGCNTTYAGYACN YTNCARAGYAAYATHYTNGAYAGYCCNGGNAAYGAYATHGARTTYATHGAYAARMGNAAR AGYATGATHAARTAYCAYGGNAGYGARGGNYTNYTNAAYYTNAARTGGYTNGCNGAYCAR ACNGCNAAYGCNAARGCNTTYGARTTYGARATHGAYGARCAYTCNGTNTCNACNMGNMGN CCNGAYGGNCARYTNGARACNGTNACNACNGTNACNGCNACNMGNACNGTNATHYTNCCN GARGTNGARGARGARGAYGCNCAYGAY---------GGNAAYGARCARCARGCNACNAAY GGNYTNATGAARGAYGARATHTAYGGNAARATHGCNCARAARYTNATHGARATGGCNGAY ACNTAYAGYGCNAGYATGTCNGAYGCNGARGGNAARGGNGCNGCNGCNATHGGNGAYGCN CCNYTNACNGAYYTNGARAARGARATHATHGCNTGYYTNMGNTCNGGNGGNGAYAARTAY GGNAARAARATGGARGAYCARYTNGAYGCNYTNAARTCNGCNGTNACNGARGAYGCNTAY GAYMGNTTYMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATHTGYTCNGGNATG GARTAYYTNAAYTGYMGNCARATHATHCAYMGNGAYYTNGCNGCNMGNAAYTGYYTNGTN GGNAARGAYGARGTNGTNAARGTNGGNGAYTTYGGNYTNGCNMGNATHGTNYTNATGGAY TAYGARTAYCAYATGTCNGARMGNTCNAARTTYCCNTTYAARTGGTCNCCNCCNGARGTN YTNCAYTTYMGNAARTAYACNGAYAARTCNGAYGTNTGGTCNTAYGGNATHYTNYTNTGG GARATHTAYTCNTTYGGNGCNATGCCNTAYAARGGNYTNACNAAYCCNGARGTNACNGAR TTYGTNGCNGTNGARAAYMGNMGNYTNAGYAARCCNCARGARGCNCCNACNCCNYTNTAY GAYATHATGATGMGNTGYTGGGARCARAGYTAYGAYMGNMGNCCNACNTTYACNACNATH AARMGNAARYTNGARAAYYTNAGYGGNAARGGNGAYTAYATHCCNATGYTNCAYACNGTN YTNTTYYTNACNTCNGTNYTNTTYGTNGGNACNTGYCAYYTNTGYATGATHAGYCCNCCN CARMGNGGNTCNATGYTNGGNATHAAYAARCCNGGNGCNACNGAYTGYATHYTNYTNACN TCNCCNTGYGGNGGNMGNGGNMGNACNGARGTNATHYTNGARYTNATHGCNGGNTCNAAY TTYACNGTNACNYTNATGAARAAYYTNAAYCAYTTYAAYAARGCNGCNCCNGGNAARTTY ACNGTNGCNATHGGNCARGAYGGNGGNACNTTYAARGARYTNYTNACNTTYCCNGAYAAY GAYGAYCCNTCNYTNACNYTNTAYACNTAYAAYGTNACNATGCCNYTNCARCAYGGNGAR ATGGTNYTNCARTCNGTNTAYCAYACNAAYAAYCCNCARGCNCCNCCNGCNTTYCAYCAR TGYAGYGAYYTNMGNYTNGTNGCNMGN---MGNCAYCCNMGNYTNYTNCARCCNCARATH ATHYTNGCNATGTTYGTNYTNCARYTNATGAARTAYGAYATGCCNGARATHAGYATHGAY TTYATHMGNAARTTYGGNCAYGTNGAYCAYAARATHGARACNYTNAGYGAYGARGTNATH GCNACNATGAAYGARACNGARYTNATGGTNACNGTNCAYAGYTTYYTNGAYAAYGCNGAY ATHYTNTGYMGNMGNAARATHMGNATGGGNCAYATGGGNGAYGGNGGNTGGGARYTNTGY GAYGAYGARGGNYTNMGNCCNMGNACNCCNCCNTGYYTNGTNTAYTCNTTYGGNYTNGTN GCNGAYTAYGCNTTYGARGAYGAYGTNTCNMGNATHTAYAARTGYGARATHCAYTCNTTY AAYCCNAAYYTNCARGGNACNGAYTTYAAYMGNTCNMGNYTNATGTTYGTNCAYCCNTAY GGNGCNGGNMGNAAYACNGARATHACNCCNAAYGGNAARGARYTNTAYACNYTNGARGAY ATHMGNACNATHYTNGGNCAYGTNGAYATGGGNATHGAYGTNATHAARATHGAYACNGAR AGYAGYGARTGGTCNGCNYTNACNCAYATGTCNTCNAAYGGNCARYTNGAYGAYGTNMGN CARYTNYTNGTNGARTTYCAYATHGGNTTYCCNCCNAAYYTNTAYAARYTNAAYMGNGCN ATHAARATHYTNMGNGGNYTNAGYMGNYTNGGNTTYMGNAARTTYTAYGTNCAYAARAAY CCNAARGGNTCNTTYCAYCAYCCNGGNTTYCCNGTNGTNMGNGCNAARAAYTAYGARGTN CAYTAYATHAAYGCNAAYTTYYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNGGNGCN CCNTCNGTNTTYGGNTCNTCNCARGGNCARAGYTCNAGYTTYGGNGCNACNGCNAAYACN GCNTCNTCNACN---------------------------CCNGTNTTYGGNGCNCCNCCN CARCCNGCNCCNGTNTTYGGNGCNCARAGYTCNGTNGCNGCNTCNTCNCCNTTYGGN--- CCNGGNGGNTTYGGNACNCCNAGYACNACNCARGCNGCNGGNTTYAAYTTYACNGGNAAY GCNTCNCCNTTYGGNGCNTCNGCNAAYAGYACNGCNGCNTCNGGNTTYAAYTTYGGNCAR GCNCARCCNCCNTCNACNAAYCCNGCNGGNGGNTTYAAYTTYTCNGCNGCNTTYCARCCN ACNCCNAAYAAYGGNGGNTTYAAYTTY---ACNCCNGGNGGNGTNTCNACNCCNTCNTTY AAYTTYAGYGCNTCNCCNGGNACNCCNAAYATGTTYACNCCNCARAAYCCNGGNGCNGCN CAYMGNCCNMGNGTNGCNGCNMGNMGNGGNACNMGNMGNGGNMGNMGNCARATHTCNCAY ATGATHGCNTTYATHGAYCARGARGCNTCNGARAARGTNGARGARATHGAYYTNAARGCN GARGARGARTTYAAYATHGARAARGGNMGNYTNGTNCARCARTCNMGNGTNCARATHATH GAYTTYTAYGAYAARAARGTNAARAAYGTNGARYTNCARAARAARATHCARAAYTCNAAY ATGCARAAYAAYGCNMGNYTNGARATHYTNMGNAARAARGARGARTAYGTNAARGARGTN YTNGAYGARGCNMGNGARCARYTNAARMGNGTNGCNAARGARAAYCCNGARGARTAYAAR GGNYTNYTNYTNAARYTNATHATGCARGCNYTNGCNMGNYTNATHGARTCNAARGTNACN ATHMGNTGYMGNMGNGARGAYGTNCARATGATHAARAAYGCNATHCCNAAYYTNGTNAAR CARTAYAARGAYYTNYTNAAYGGNAARTAYTCNATGGARYTNGTNGTNGAYGARGARAAR TTYYTNTCNCCNGARATHTGYGGNGGNGTNGARYTNCAYGCNYTNAAYGGNAARATHGTN GTNGTNAAYACNYTNGAYGARMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MGNTTYTTYGCNGTNAARCCNTCNAARGAYATG YTNGAYTCNAGYAAYATHTTYAGYCAYGAYAARATHTTYCARYTNGTNAARAAYACNACN GAYAAYAGYMGNYTNCAYGTNATHTTYAAYAAYAARAARAARTAYACNTAYCARTTYGAR TCNGCNYTNYTNMGNGARAGYTTYTGYYTNCARATHMGNCARATGAARTCNYTNCAYTCN GARGARCARGAYATHGAYAAYATHTCNATHTTYATHGGNACNTGGAAYATGGGNAARTCN GCNCCNGTNGARTCNYTNAARTAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CARATHATHACNAAYGCNGCNTCNGTNCCN---ATHGTNTCNACNGCNCAR GGNGGNACNATHYTNCARTCNAAYAAYYTNYTNMGNAAYGTNACNCARCARCARACNCCN CARGTNTCNCARCARCARACNGTNCARGCNGCNGGNACNTCNACNCCNCCNGTNGGNACN AAYGCNGCNGGNATHCCNCARATGYTNTTYYTNAAYCARGTNACNATHAAYGGNCARACN TCNTTYGTNYTNGTNGAYGCNAAYAAYAARCCNATHCARYTNCCNCARGGNATHCARGTN ATHAAYYTNCCNCAYCARCARATGTCNGGNCARTCNATHCARATGCCNGGNGGNGAYACN GGNGAYGARCCNYTNTAYGTNAAYGCNAARCARTAYCAYMGNATHYTNAARMGNMGNCAR GCNMGNGCNAARYTNGARTCNGARGGNAARATHCCNAARGARMGNCARAARTAYYTNTAY GARTCNMGNCAYMGNCAYGCNYTNAAYMGNGCNMGNGGNACNGGNGGNATHTTYGTNGGN CAR------------------------GTNGTNGGNAARAAYAARATHCCNGTNAGYYTN AGYGTN---------GARGAYGGNAGYGAYGGNCCNACNYTNCAYMGNYTNTGYCARACN ATHCARYTNCAYACNAGYATHCCNCCNCCNGCNCARAARATHATHTAYMGNGGNMGNACN YTNTTYAARACNTTYGAYCCNGAYGAYCCNAGYYTNAARAARAGYYTNTCNTCNYTNGGN ATHAARAAYGGNGAYMGNATHATGGTNTTYGGNAARCCNTCNGTNGAYGARAARGARAAR GARGGNAGYGAYCCNAARGARGARYTNATG------AARGTNYTNGAYCARCAYCARGCN AARGTNGARGAYATHTGYGTNYTNTGYMGNAAYACNGTNGAYCARATHGGNAAYCCNGGN ACN---ATHGARGAYTGGAARAARCAYAARAARTTYTTYYTNGGNCARTCNGARTAYTCN ATGCARGARYTNACNMGNYTNGAYGCNACNCCNGGNGCNYTNTCNCARCAYGGNGAYTAY AARGCNMGNMGNAARGCNYTNGTNAAYGCNYTNYTNGARAAYATHAGYYTNTGYGAYAAY CARGTNTCNMGNYTNGAYMGNTCNATHCARGARGTNGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GAYAAYYTNAARYTNGAYGTNATHYTNACNACNGGNGGNACN--------- ------GGNTCNCCNMGNGAYGTNACNCCNGARGCNACNAARGCNATHATHGARAARGAR GCNYTNGGNATGGCNGTNGCNATGATHAARGGNTCNYTNMGN------------------ ---------------------------ATGGGNAARAARCAYAARCAYGGNAARCAY--- TCNTCNTCNTCNTCNTCNTCNTCNAGYAGYGAYTCNTCNGAYGAYGARTGGMGNCAYYTN CCNAARCAYGARAARAARATGMGNAARAARTGGAARAARCARATGMGNAARGGNCAYATH GCNCAYGGNACNATGCCNCCNTGGCAYGGNGGNCCNATGTGGGCNCCNCCNATGAARGGN CAYAARGGNGGNAARGGNGCNAARGGNGCNAARCCNACNGGNACNCAYCCNCCNCCNCCN GGNTAYCCNGGNCARCCNGGNTAYCCNGCN---------------CARCCNGGN---TAY CCNGCNCARCCNGGNTAYCCNGCNCARCAYGGN---TAYCCNGGNCARCARCCNGGNGCN TAYCCNGCNCCNCAYAAYCCN------AGYTAYCCNCCNCCNCCNGGNGGNTAYCCNGGN GGNCCNGCNCCNGGNGGNTAYCCNGCN---------CCNGGNGGNCARTAYCCN------ ---CCNCCNCCNCCNGCNCARTAYGGNCCNCCNCCNGGNGCNGCNTAYGGNGGNCAYGGN GCNCCNTCNGGNCCNTTYCARGTNCCNCCNGGNAGYGCNTAY------CCNCARTCNGGN TAYCCNCCNCAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GCNATHCAYGARGARAARTCNAAYGCNGARGTNMGNYTNMGNGAY AAYYTNGARMGNYTNGAYCARYTNGARTTYGARAARACNATGATHGCNGARCAYGCNTCN GARYTNCARGGNACNATHCARGAYYTNGTNTCNCARAARGARATGACNGARAARGARYTN AARGARGARATHMGNGCNMGNATHTCNGCNGARGARMGNYTNAARGARGCNGARMGNTCN YTNAAYTCNYTNGAYCAYGCNGTNCARACNCARGCNCAYMGNATHGARGARGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TGYTTYAARYTNGGNTGYTGYGCNGCNTGYATGAAYACNAGYYTNCAY AARYTNYTNMGNYTNTCNGAYGTNTGGTCNACNGTNTGYYTNTAYTTYGTNYTNTGYTTY GCNACNATHGGNYTNGARGAYATHTTYCCNGTNTTYGCNTCNACNACNACNGAYAAYGGN GGNYTNGGNTTYTCNGCNAGYGARATHGGNACNGCNYTNGGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MGNAGYCARTCNGAYTCNGTNGAYCCNMGNMGN TCNGARCCNAAYTTYGGNMGNTTYTAYAAYACNAGYTAYYTNGGNYTNAAYGCNGGNAAR GCNTAYACNAAYAARACNAGYGCNAAYGCNGCNGARAARAARGAYGGNAARACNGGNGCN CAYTTYCAYMGNCCNCCNAAYTTYACNTAYGCNAARCARCCNCCNACNTTYYTNAARAAR AARGGNACNGGNATGTCNGCNYTNACNTCNGTNCARMGNGTNGTNAARGTNMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYATH YTNCAYTTYGTNTTYAGYACNAARGARGTNCCNACNGTNYTNATGGCNMGNACNACNAAY TCNGAYACNAGYATGACNTTYAAYTGGGAYGTNYTNYTNAAYAAYACNTCNATGATHGAY GGNATHAARTTYCCNGAYAARATHAAYATHGGNTAYAARTTYGGNTTYAGYTTYACNAAR YTNATHGARTAYGAYGAYMGNAGYGAYGAYGCNGAYYTNACNGAYTGGGARAARAGYAAR AARAARYTNAARACNMGNTCNTTYAARGARTTYATGTGGGARCCNYTNGAYAARGAYATH AARAARAAYAARTTYYTNTTYAAYACNACNGAYGAYGCNATGCCNCAYGARAARTCNAAY AAYGGNAGYYTNTCNTTYGCNTTYCAYGTNCCNGGNGARGARGGNMGNYTNTCNTCNYTN CCNTCNCARAARTAYACNGCNAAYGARACNGTNYTNGARTTYYTNYTNGAYAARTAYACN CCNTCNTGGAAYAARTCNMGNTTYGCNYTNGARGCNGTNGCNGTNAGYYTNGGNGCNAGY AARAARATGGAYGTNAARACNATHGARACNATHGAYGAYGARTAYTCNCCNGGNGTNTTY YTNYTNACNAAYTGGYTNACNGAYCCNTCNGAYAAYTCNAARTCNGGNTTYGTNCARTGG AARCCNGTNTCNTAYTTYGGNAARACNMGNGGNMGNAARACNGTNACNAARGTNAARCAY TAYCAYYTNCARCARYTNAGYGARGAYGARACNYTNAAYGCNACNYTNYTNTCNGCNYTN TTYGGN---GAYYTNTTYGAYGGNCAYACNGAYGTNAARAARATG---AAYATHTCNTTY GGNCARCCNAARGAYGAYTAYTAYYTNAARAAYAAYTAYACNGTNTGGAAYAGYGCNATH GGNTAYGGNACNCCNCCNAARGAYGARATHTCNYTNACNGTNATHATHATHATHTCNACN GGNYTNGGNATHCCNGTNYTNGTNTGYATHGTNGGNGGNATHTAYACNATHTCNMGNGCN GTNMGNAAR---AARMGNTCNCARTAYGARGCNATHAAYGGN---GGNCCNATHAAYGAR GAYMGNCCNCARGTNAAYATHAARATHYTNGARTTYGTNYTNTCNATHTTYGCNTTYGCN ACNACNACNAGYCCNGARACNTCNACNACNTTYACNGTNCAYAAYTGYTCNACNTGGACN AAYAAYACNTAYATGGGNTCNGCNTCNMGNACNTTYTCNTAYAGYTAYCCNTAYGAYYTN GARGARACNTGYTTYAARGTNCCNATHTGYAARGGNAAYYTNCCNAAY---------GAY GARTTYTGYYTNYTNGARGGNTCNCARTCNGCNGCNCARTTYTAYGTNTTYGTNGGNGTN ATHGTNTTYYTNTAYTGYYTNGGNGCNYTNGTNYTNTAYGTNTTYTAYGAYGARACNTAY MGNMGNAAYTCNMGNATHGTNYTNGCNGAYTTYATHGTNTCNTGYGTNYTNACNYTNTTY TGGATHATHTCNTCNTCNGCNTGGGCNGCNGGNYTNGAYGAYGTNAARYTNTAYACNGAY CCNTAYGAYGGNGGNATHTTYCARGAYAARYTNCCNGARTGY---CARYTNAARGGNTCN TGYTCNACNACNAARGARGGNAAYTTYGCNAGYYTNAAYGTNTCNATHATHTTYGGNTTY YTNAAYTTYGTNGTNTGGYTNGGNAAYYTNTGGTTYYTNTAYAARGARACNCCNTGGTTY AARGTNCARGCNAARCCNCCNACNCARCCNYTNTCNAARGCNCARYTNGARTGYGARTGG MGNYTNGCNTCNTGYYTNAARAAYGARAAYGARCAYATHCARAARAARYTNAARGARAGY GGNGAYYTNTCNTCNTTYTTYAARTAYTTYATHGARATHGCNGARAARTGYYTNCARGTN ACNGGNATGCCNGARMGNCCNTGGAAYGAYTAYAAYCARAAYATHYTNAAYCARYTNCAR AAYATHGGNTGGAAYAARGTNACNCAYYTNTCNGAYAAYTTYTCNAGYGTNGARATHAGY TGYTAYGAYMGNAGYCAYMGNAAYCAYAARYTNAARGTNAAYTTYAAYAARAARAAYTGY CARGCNMGNCCNGAYTGYATGACNGAYYTNCCNCARGARTTYGAYTTYCAYTGGTCNTCN ACNGCNCARYTNAAYGAYYTNGTNYTNCARTTYGARGGNTGYYTNGGNAAYTAYGARGAR TTYTGGAAYATGGTNGARGARATHGAYMGNAARACNTGGGTNYTNGARCCNGARCAYCCN YTNTAYTCNTGYACNTAYMGNMGNATHGCNYTNGGNCARAAYYTNTCNYTNCAYATHATH ATHAAYCCNYTNCARCCNTCNAGYYTNCCNGARTGYMGNATHYTNGGNTCNGARTCNGCN GTNGCNCCNYTNMGNGARAARYTNAAYGTNAAYYTNCAYYTNTGGGAYYTNGAYMGNTCN YTNYTNAAYAAYYTNCARGARGTNYTNGARATHGAYTTYCCNGCNCCNTCNGAYACNACN AARGARGARYTNAGYGTNGAYTGYGGNATHTGYTAYAGYCAYCAYYTNGGNGARGARATH CCNGAYATHGTNTGYCARCAYCCNCARTGYAGYCARTCNTTYCAYTAYACNTGYYTNTTY GARTGGYTNMGNAAYTCNTCNTGYMGNCARAGYTTYAAYTAYATHTTYGGNGARTGYCCN TTYTGYAGYAARCCNATHMGNGTNAARATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CARCARCARCARCARCARCARCARTGGTGGCCNGGNAAYAAYCAR---YTNTGGATG CARCARCARTTYGCNCCNCCNAGYCARGGNTAYGGNAGYGAYAGYAAYAGYGGNGGNCCN ATHTTYCCNCCNAAYCARGAYACNCCNCAYAARGGNGARGCNTTYAAYCARTAYTGGGAY ---------------GAYTCNGARCARAAYGGNGARGGNMGNMGNGARCARCAYMGNCAY CAYCCNTCNCAYCAYTCNGAYCAYCAYCAYMGNCAYCAYCAYCAYCAYCAYCAYMGNYTN CAYMGNMGNGAYMGNATHGGNGAYGCNMGNAGYYTNGGNATGGTNGAYGAYGAYTCNTCN GGNYTNGAYGCNGCNAARMGNAARACNYTNCCNYTNTGGYTNMGNGARGGNYTNGARAAR ATGGARMGNGARAARCARAARCARYTNGARAARGARCARYTNAARATGCARGARGARACN TTYGGNAARGAYCARGTNGARGARGARGAYGAYGAYGGNCARCCN--------------- ------------AARGTNCCNMGNAARAGYMGNTTYGAYTCNGAYGAYGARGAYGARGTN TCNGAYAARAARGCNGAYGARGAYGGNACNGGNGTNGAYGGNGAYAAYGAY--------- ---------------GTNCCNAARCCNCARCARGARCCNCCNAARTCNTCNCCNAARAAR MGNAGYCCNTCNCCNTCNGAYTTYATGACNGARGARGARMGNGARYTNGCNYTNATGATG AARGTNAARMGNATGYTNACNGARACNYTNYTNGARGTNACNGAYCARGARATHMGNAGY ATHGCNGCNGARGTNCAYCARAARGARAARAARAARGCNCARAARGCNCCNGCNAARCAR YTNGCNAARTCNTCNGCNYTNGCNTCNYTNTCNAGYYTNGGNYTNGGNTAYGGNTCNGGN TCNGARACNGAYGAYGARGAR---------------AARGARGAYTCNGAYAGYGAYYTN GARGARMGNATHAARMGNMGNAARGCNGARTTYGCNAARACNCARAARACNGCNAGYGAY TCNGARGGNGAYAAY---------GAYGTNAARTCNAAYTCNGGNMGNATGAARACNGAY MGNGAYAGYAARACNAARACNTCNAARGARGAYATGAARTCNATHTCNMGNGAYAARGAR GAYMGNACNGAYMGNMGNTCNAAYMGNGAYGTNAARGAYMGNMGNGAYAGYMGNGAYAGY GTNAARMGNGGNAAYACNAAYAGYMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTAYAAYGGNATHGGNYTNCARACN CCNMGNGGNAGYGGNACNAAYGGNTAYGTNCARMGNAAYYTNGCNTTYGTNAARTCNAAR AARGAYMGNGTNGAYTAYAARGAYGARGAYGARYTNAARAARYTNGARCARTCNATGAAY AARCARCCNAAYCARGARATHYTNGAYCAYGARMGNAARMGNAARGTNGARYTNAARTGY ATGGARATGCARGARYTNATGGARGARCARGGNTAYACNGAYAARGARGTNATGGAYAAR GTNAAYATGTTYMGNAARATGYTNATGGCNAARGARGGNGTNTCNGAY---ACNCCNATH GARAARGAYGARCAYGGNMGNCCNATHGCNAARGARACNCAYCARYTNGCNGARGCNAAY CARATHAARAAYGAYAARYTNAARGARGCNTTYGGNYTNTCNGAYTAYACNGAYGGNAGY GCNTTYGAYCCNGAYMGNAARGCNAARGARGARCARGCNMGNGCNYTNGCNYTNGCNCAR AARCARTAYAGYATHGTNAAYAGYTCNGAYGARGAYGAY------AARGARAGYTCNCCN GTNCCNAARAARAARAARAARAARTCNMGNCAYGAYGAYGGNTCNTCNCCNGARMGNAGY AARGARAARMGNAARAARAGYMGNAARCAYAGYAARMGNGAYMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARGAYYTN AAYAARTCNMGNGCNAAYTAYGCNGARYTNGARTCNACNATHGGNAARYTNAARGCNAGY YTNCARACNAAYACNTCNAAYCARAAYAARGAYMGNAGYMGNATHCARGARYTNTCNGAR GARATHATGAARYTNGTNAARMGNCAYAARYTNTAYCARMGNYTNYTNTCNGGNCAYATH GTNATHCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TTYAAYTTY CCNTTYTAYGGNCAYCCNGTNAARAAYGTNACNGTNGCNACNGGNGGNTTYATHTAYATG AGYCCNTTYYTNCAYCARTGGYTNACNGCNACNCARTAYATHGCNCCNYTNATGGCNAAY TTYGAYCCNTCNYTNGAYTCNAARTCNAAYATHTTYTAYYTNAGYGARGARGARATGTTY ACNGTNGARTGGMGNGAYGTNTTYYTNCARGAYCAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------MGNGCNGARATHTCNTCNTGGYTN GGNAARGTNATHAARAAYGARCCNATHCCNGAYTTYGARATGAAYGCNCARACNATHCAR YTNYTNCAYAGYYTNTCNGTNGTNAGYCARTAYAAYGARAARAAYACNCARYTNTAYATH GARGAYATHAARAARAARYTNGARGARTAYAAYGCNGAYGCNCARMGNATHGGNAAYGTN YTNGAYMGNYTNACNYTNGGNCARAAYAGYYTNTCNMGNTCNGGNTCNTCNTGYYTNCAR GCNYTNGCNMGNACNGGNGCNTCNYTNAGYGTNAARGAYGCNTCNGAYTCNTGYTAYYTN YTNTCNATHCARGARYTNCAYYTNAGYGTNAAYGARYTNACNGARAARYTNCAYTCNGAR AAYCARGAYYTNCARMGNATGTCNMGNAARACNCARAAYGTNYTNATGAARCAYAGYTCN YTNAARAARGCNYTNGARGTNYTNGAYAARMGNTCNTCNCARGARGCNGCNMGNATHGCN GARMGNAARAARGARACNGGNATHGTNAARAARGCNACNGCNGARAAYGAYACNACNATH GARAARYTNAARACNAARYTNGCNCARTCNGGNYTNAGYGARTCNGAYTTYCAYGAYAAR YTNGTNAARAARAARGARAARYTNAAYGCNGTNGARAGYGARYTNGCNCCNYTNAARGAR GARYTNCARTCNTTYACNAGYYTNCCNCCNGAYGCNATHGARGCNAARGTNCARATHGAR CARYTNAARMGNGARYTNAGYMGNYTNCARACNCARATGTCNGARTGYGTNGAYGTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNAARTGYYTNGAYGAR GARMGNAARMGNATHAARGAYMGNYTNYTNGGNAARTAYATHAARAARGARACNAARGAR GARYTNGARGCNGCNCARACNCARTAYATHGARCARYTNGARMGNTAYGARGAYAAYCAY YTNGGNAAYTTYMGNMGNATHTTYCCNYTNCCNGGNACNGAYAARTAYGAYAARTAYTTY CAYAGYAGYGGNACNYTNTTYCARGARACNGCNGCNTTY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNATHMGNMGNGTNGTNGGNGGNCARCCN GTNTCNMGNGGNACNTGGCCNTGGYTNGTNTCNYTNAAYTAYCARGARCAYCAYCCNTAY YTNGARYTNCARGGNYTNGAYCAYYTNTGYGGNGGNACNYTNATHGAYCCNAAYTGGGTN YTNACNGTNGCNCAYTGYGTNCAYCCNYTNYTNGGNAAY---GGNYTNGGNGTNCCNTCN AAYTGGATHGCNGTNYTNGGNGARTAYCAYMGNMGNGTNGARGARTCNTCNGARCARMGN YTNCCNGTNGARGCNATHTAYATHAGYCCNAARTTYTCNTGGAAYCCNAARTTYACNGGN GAYYTNGCNYTNYTNAARYTNAGYCARCCNGCNACNYTNAAYAGYGAYGTNMGNCCNATH GCNYTNGAYGAYGGNATGTTYATHCCNGAYGGNGCNGARTGYGAYGCNGCNGGNTGGGGN CARCAYGCNGARGCNGGNTCNCCNGAYCCNCARTTYGGNAAYGGNACNATGGTNCCNCAY TTYGTNACNYTNAARAARCARGAYCARGGNAGYTGYAARGCNCARTAYMGNTCNACNTTY TTYGGNATHGAYGCNACNGTNATGTGYTTYTCNTCNGAYGARMGNAARGAYACNTGYCAR GGNGAYTCNGGNGGNCCNYTNGTNTGYCARAAYCCNYTNGGNATGGGNGTNYTNTCNGGN GTNGTNTCNGCNGGNCCNGGNTGYGGNMGNGARAAYTTYTCNGGNYTNTAYACNMGNGTN TCNAGYTAYTAYCCNTGGATHCARCARACNATGGCNTCNCAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TGYAGYMGNCARACNCCNTCNMGNGTNATHATHCARGGNYTNGAY TCNGCNGGNAARACNACNYTNYTNTAYMGNYTNAARYTNGGNGARGTNGTNACNACNATH CCNACNATHGGNTTYAAYGTNGARAGYATH---GARACNMGNGGNYTNGARATHACNGCN TGGGAYYTNGGNGGNMGNGAYAARGTNMGNCCNYTNTAYMGNCAYTAYTAYAGYGGNACN GARGGNTTYATHTAYATHGTNGAYAGYTCNGAYGTNGARMGNYTNGARGARGCNYTNACN GARYTNCAYGAYATGATHYTNCAYGAYGAYGAYTGYMGNAAYTCNGTNGTNATGYTNYTN GCNAAYAARCARGAYYTNGARCAYGCNYTNAGYCCNGCNGARATHGARCARAARTTYCAY GARAARTGYAAYYTNGARTTYAAYGCNTCNYTNTTYGTNATGCCNTGYAGYGCNACNTCN YTNGAYGARAARCCNATGTGGCARGCNTTYAAYTAYYTNGTNAARATGATHATGYTNAAR AARGARGGNMGNYTNGARAAYGGNTTYATHCCNYTNGCNGCNAGYCARGARGCNGARAGY AARAARATHGTNGAYGAYGTNGGNYTNTTYCAYAARYTNGTNTTYAARAAYCCNYTNCAR YTNGTNAARTCNTTYYTNTTYTAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AGYGGNYTNATH GGNMGNAGYTTYACNATGYTNTTYGCNAGYGCNGGNTAYGAYGTNACNATHTTYGAYYTN GAYCCNAARCARACNTCNGCNGCNAARGCNGAYATHMGNATHCARYTNGCNAAYYTNGAR AGYCARGGNYTNYTNMGNGGNAARTTYTCNAARGARGARCARTTYAAYAARATHTCNACN ACNGARAGYYTNGARGARTGYGTNAARGGNGCNTTYTTYATHCARGARTGYGTNCCNGAR AARYTNGAYATHAARMGNTCNYTNTGGTCNAARGTNGAYAARYTNGTNGAYGGNAARGTN ATHATGTCNTCNTCNACNAGYGCNYTNYTNCCNTCNGCNATHTCNGAYGGNYTNGAYCAY AARAAYMGNTTYATHGTNTCNCAYCCNTGYAAYCCNCCNTAYTAYGCNCCNGCNACNGAR GTNGTNCCNGCNAARTGGACNGAYAARGARGTNACNACNMGNACNATHGARGTNYTNAAR GARGTNGGNCARGTNCCNGTNYTNATHAARAARGARATHGAYGGNTTYGTNYTNAAYMGN YTNCARTAYGCNATHATGGGNGARGCNTAYAARYTNGTNAARGAYGARGTNGTNAGYGCN AAYGAYYTNGAYGTNATHATGTCNCARGGNYTNGGNATGMGNTAYGCNTTYATGGGNCCN TGGGARACNGCNCAYYTNAAYGCNGARGGNATGYTNGTNTAYGGNGARMGNTAYGCNGAY ATGATHYTNGGNATHCARAARAGYTTYACNTCNCCNYTNMGNATGGARGGNGARACNYTN CARGTNATHCAYGARGAYATGYTNACNATHGCNGGNCCNYTNGARGAYATGCARGCNMGN MGNCARTGGMGNGAYMGNMGNYTNGTNGGNYTNGCNCARYTNAARGCNAARACNAAYAAR GARGAYGCN---GAYGTNGTNTTYTCNTTYGAYACNACNGGNTCNATGTCNCARGCNYTN GAYGARGTNAARGCNMGNGTNATGGAYATHATHCARAARYTNCARGCNGAYATHCCNGGN GTNMGNACNGGNATHATHGCNCAYGGNGAYTAYTGYGAYAARGARCAYTTYTAYGAYATH MGNTTYYTNGAYYTNTCNGAYGTNGTNGCNGAYGTNGTNACNTTYGTNAAYGAYACNGAR GGNACNGGNGGNGGNGAYGTNCCNGARTGYTAYGARYTNGCNYTNMGNCARGCNAARAAY ATGGCNTGGMGNGTNGTNGGNAARMGNATHYTNGTNATGATHGGNGAYGCNTAYCCNCAY GARCCNGAYTAYCCNYTNAAYGARCARAAYATHGAYTGGMGNAAYGARYTNGCNGAYYTN GTNGCNATGAAYGTNCAYATHTAYGGNGTNCARGTNCARAAYGAYGARYTNAGYACNCAR TTYTTYAAYGARYTNGCNACNGCNTCNGARGGNCARCAYYTNCARYTNGCNAAYATGGGN MGNATHTGYGARGTNATHATGGGNATHTGYTAYMGNGARCARGGNCCNGTNATGTTYCAR AAYTTYGARGCNGARATHMGNCAYAARGARCCNGARAARTTYGGNCCNGAYYTNGARTGY GTNTTYGGNACNYTNMGNCAYGARGTNTCNTCNTCNTCNTCNTCNGCNGCNACNCARGAY AAYTCNTCNTCNCARTGYGCNATHTGYYTNTCNGARTTYAAYGTNGGNGAYTCNAARMGN ATHYTNCCNTGYCARCAYGAYYTNCAYAARGARTGYATHGAYCARTGGYTNAARACNAAY GCNACNTGYCCNATHTGYMGNAARGAYATHMGNTAYAARCARCAYGCNMGNGCNAGYATG YTNAAYGAYTAYYTNGTNTTYAARGCNGAYTAYYTNACNAARACNYTNGARGARCAYAAY TTYCAYTAYTAYYTNGCNTCNAARAARGTNTAYGAYATHYTNGTNCARACNCCNGTNGTN GARMGNMGNYTNCAYMGNMGNTTYATGAARACNMGNMGNAARAARYTNCCNGTNCCNACN GARAAYGAYGARTAYTTYTTYCAYGARCAYTGGTTYACNCAYAAYGARYTNAARATHGAR GAYTAYAARAARGARAARGARGCNGARMGNCARGCNAARGTNGARGARGCNMGNGARAAR GGNCARYTNTAYGARTGYTGYTGYTGYTAYGARGAYGARTGYYTNTTYGARGAYYTNGCN AAYTGYCCNGARGGNCAYYTNTTYTGYAARGTNTGYGTNATHMGNTCNACNGARGCNGCN TTYGGNGARATGAARACNMGNTTYCCNTGYYTNACNGGNGARTGYGAYCARGCNATHCCN YTNAGYACNYTNCARGGNATHGTNCCNCCNAAYTTYTTYTCNAARATHGTNAGYMGNYTN CARGARGARGARGTNYTNCARGCNCARATHCCNGAYYTNGTNACNTGYCCNTTYTGYCCN TTYGCNACNATHATGCCNGAYCCNGAYGAYAARGTNYTNMGNTGYYTNAAYCCNGARTGY YTNAARGARTCNTGYMGNYTNTGYCARGARGARAGYCAYATHCCNYTNAARTGYAGYGAR GTNGARAGYMGNGCNGGNACNAAYATGMGNACNTTYATHGARAAYAARGTNGCNGARGCN GTNATGMGNAARTGYCAYAARTGYGGNAARMGNTTYYTNAARGAYTCNGGNTGYAAYAAR ATGACNTGYGTNTGYGGNGCNACNAGYTGYTAYTTYTGYAARGARCCNAAYATHAAYTAY GAYCAYTTYAAYAARAAYAARAARTGYGCNCARACNCARCCNAAYYTNATHCAYGARMGN GAYATGAARGARGCNGCNAARAARGCNATGGARGARTAYATHYTNGCNCAYCCNGARGCN GCNGCNYTNGAYYTNYTNACNTGGTGYMGNAAYGTNACNTTYACNAARGCNYTNMGNCAR GARGAYCARATHGAYCARCCNGARGAYACNGAYGGNAGYATHCCNAARMGNAARGTNGTN GAYGTNGARACNAGYATHMGNTAYYTNAAYAGYAARGCNTTYGAYGCNGGNTAYGGNGAY AARCCNGTNTGGTTYCAYTAYMGNMGNAAYTTYAARAARAAYATHATGCCNCARACNMGN AARGAYTGYATHMGNMGNGGNGARATHGCNACNGCNAGYCCNTGYCCNGTNTGYMGNGAY GARTAYYTNGTNYTNGAYGCNAARAAYATHAARYTNYTNGARCARTTYATHTCNCCNTAY ACNGGNGARATHTTYGAYTCNATGAARACNGGNYTNTGYCARAARCARCARMGNAARYTN ACNGTNGARGTNATGMGNGCNTGGGAYCARGGNTAYYTNGARATGAARGTNCCNTTYMGN ACNTAYGAYTAYAGYGAYTAYAARAGY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNATGACNGARGCNMGN GCNMGNCARMGNAARYTNAGYMGNTCNAARACNMGNCCNGGNGTNACNCARMGNAAYATH AARCARAARTTYMGNGCNYTNYTNAARAARTTYAARATHTCNGARGAYGCNYTNGTNGAY TCNGARGCNGAYCAYGAYCARATHCCNAAYCCNYTNGAYGARYTNTTYGAYGARYTNGAY GAYTCNGAYTCNGGNCCNGARYTNGAYACNATGAGYGTNATGTCNACNCCNAARCCNAAR YTNMGNCCNTTYTTYGCNAAYMGNGGNGGNACNACNCCNGGNATHGCNATHCCNAARACN ACNTCNCARGARGCNTTYMGNTCNCARGARGARACNCCNGTNAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYGGNAARAGYACNGCNCCNCAYGCNTCNATHYTNGCNCCNGAYGAY GTNACNATHCAYACNTAYCCNTGYATHCCNGAYTAYAAYCAYCARAARGTNATHATHGTN TTYCCNGARATGGAYCAYCCNACNACNACNAAYGGNTCNTGYGAYGCNAGYGTNMGNGAR GGNAAYGTNAARGAYGAYATHGCNGTNAAYAAYAAYAARGGNYTNGAYACN---YTNACN MGNTGYAAYAAYGTNTCNCCNGCNTCNGARGCNACNGARCCNCARTCNAGYACNTCNAAY CARAAYTCNGTNTCNGAYTTYAAYMGNGAYTCNAARMGNAARMGNACNYTNAGYAAYGAR GAYAAYGGNAARAAYCARAGYGTN------------------------------------ ------------------------------CAYAGYGAYAGYGARTGYGARGARTCNGGN CCNTCNGTNGTNAARCAYCARAARACNMGNYTNMGNCARTGYCCNTTYGAYAARGTNGTN TTYGTNGAYTGYACNTGGAAYCARACNAARCARATHGTNACNGAYGARMGNYTNAARGGN YTNAARAARGTNGARYTNAARTCNCARTTYACNCAYTTYTGGMGNACNCARGAYGGNATG CCNAARACNTAYYTNTCNACNATHGARGCNATHTAYTTYTTYTTYMGNGAYTTYCAYACN ATHTTYGTNGAYCCNGTNTAYMGNCAYCARTAYGAYAAYYTNYTNATGTTYTTYTGYTTY ATGTAYCAYAARATHAARCARAGY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TAYGGNGCNATHACN MGNCCNTCNGAYTTYGCNAGYTAYYTNYTNGCNATHTTYATHGGNAAYYTNYTNYTNTAY TGYYTNTTYTAYGTNATHATGAARYTNYTNAGYGGNGARTCNATHAGYYTNYTNGTNATH GGNGTNATGYTNACNTCNYTNGTNTCNTGGGGNTGYTCNYTNTAYTTYTTYTTYCARCAY GTNACNTCNTGGCARAARACNCCNTCNGGNTCNMGNGARGGNAAYMGNGARTGYATHYTN YTNGAYTTYTAYGAYTCNCAYGAYGTNTGGCAYTTYYTNTCNGCNTTYAGYYTNTTYTTY TCNTTYATGATHYTNYTNYTNYTNGAYGAYAAYYTNTCNGTNACNCCNMGNAAYCARATH TCNGTNTTY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNAARGARGTNCARGARGARMGN GAYMGNYTNYTN------GARGAYCARGCNAAYAGYAARATHAARGARYTNCARGARMGN YTNGCNATHYTNGCNMGNTCNAAYGARGARAARGARCARYTNATHCARMGNYTNAAYGAR GARYTNAARGTNACNAAYYTNMGNYTNAARGAYACNGARAARAARYTNGCNYTNTCNGAR GCNGCNAAYGCNTCNCAR------GCNCCNAARTCNAARACNTGYGTNYTNATG------ ---------------TAYMGNGTNTTYTAYACNGCNYTNACNAARTTYACNGARGARATH CCNAARMGNYTNAARTCNTCNGCNCCNAARGCNGTNTCNTCNAAYATHGCNGCNGTNACN AARATHYTNCCNCCNGGNGAYAARGCNTTYACNYTNCAYTAYATHACNGCNATHAARAAR MGNGCNACNYTNACNYTNAAYGTNYTNGCNAARTAYYTNGARGAYAARTGYAAYTAYGTN AARGARGAYGCNCARAAYTGGTAYAARAGYCARMGNYTNTCNYTNGGNTTYGCNATHGCN GTNAAYMGNYTNTCNATHAARAARYTN---------GTNGARTCNGAYGTNGAYGTNGTN GGNTCNGGNATHGGNGGNATHAAYAARGGN------------------------------ ------------------------------CARYTNTCNACNTTYAARAGYGAYYTNAGY YTNGARAARATGTAYCCNAAYTCNGAYATGGAYTAYYTNMGNAARAAR---------CAY GAYGGNGARATGGAYATGGARAARTTYTCNGGNTAYATHCCNGTNGARCARYTNGARATH AGYCAYAGYMGNAGYAGYGGNCCNGGNGGNCARAAYGTNAAYAARGTNAAYAGYAARGTN GARGTNMGNTTYCAYYTNGAYTCNGCNTCNTGGATHCCNCARTGGATHAARYTNAARYTN ACNGARCARGARCARAAYMGNATHACNAARGAYGGNTTYYTNATHATHMGNTCNGAYATG ACNMGNAARCARATHYTNAAYCARGCNGAYTGYYTNAAYAARYTNMGNAAYATGATHTAY CARGCNTCNGTNYTNCCNGARGARCCNACNGARGARGARATHAARAARAARGARCARMGN ATGATGAARGCNAARGCNGGNATHYTNMGNGARAARAARAAYMGNTCNYTNYTNMGNAAR TCNMGNTCNAAYCCNGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARTTY CAYGGNYTNTTYCCNYTNGCNTCNTGYYTNAAYCAYTCNTGYTAYCCNAAYGCNGTNGTN GARAGYGCNCCNATGGGNACNMGNCCNGGNATHGCNGTNAARGCNGTNMGNGAYATHMGN GARGGNGARGARGTNYTNATHGCNTAYGTNGARCCNCARATGGARMGNCAYGAYMGNMGN AARATHYTNTGGAARAARTAYAARTTYGTNTGYGARTGYCCNMGNTGYYTNCAYCARGGN ATHGGNCCNCAYGTNTGYACNAAYTGYGGNAARACNGCNAAYGAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GGNGGNAGYYTNTAYAGYAGYACNGARTCNATHAAYAARGTNGCNACNGAYGCNAARGAR ATHCARYTNGARGAYATGGARGTNGAYGARGAYYTNCAYGTN------TAYYTNACNATH YTNATGGGNGAYTCNGGNACNTCNCARTGGYTNTCNTCNATHATHGAYYTNAARAAYGCN GTNATHGGNAGYAAYMGNGARAARTCNMGNGCNGTNGARCARGGNYTNGTNCCNMGNYTN YTNGGNTGGATHGARGAYGGNYTNTGYCCNYTNGAYYTNAARACNGARGCNGCNATHGTN YTNGGNAGYYTNGCNAARGGNMGNCARGAYACNGTNCARAARYTNGTNGAYGCNAARGCN GTNTCNGTNYTNTTYAARTCNYTNAGYATHTCNAAYYTNAARTAYTGYGARGCNGTNYTN MGNTGYYTNMGNTCNATHTTYATHGARAAYACNGAYTGYATHGAYATHYTNTAYGARGAR AAYAGYTTYGGNCCNTCNTAYATHCCNACNYTNYTNGCNATGACNCARCARTCNYTNGTN TGYCARGARTGYGTNACNAAYATHYTNGTNTGYTGYTGYAARACNMGNGARCAYCARATG TCNYTNYTNAAYAGYCARGCNYTNCCNATHYTNTCNCCNYTNYTNCARTCNAAY---CAR TAYAARATHCARATGCCNACNYTNMGNTTYTTYGCNAARGTNTGYCAYAARAAYTGYGAR GTNTGYACNGAYATHGCNAARGAYAAYAARYTNGTNGARACNTTYGTNGGNYTNATGAGY TGGGAYAARTCNACNGARATGCARYTNTCNGCNGCNGARATGYTNACNAAYATGCAYMGN TGYGGNGTNATHGCNGCNAGYGAYTTYATHGTNAGYMGNAARACNYTNGGNACNYTNGTN MGNATGTGYATGAARGAYMGNAGYGTNGARGARAAYGTNMGNGGNGCNGARATHYTNGCN TAYYTNATHGARATHGAYCCNGAYYTNCARYTNATHGCNAGYTAYACNTTYCAYYTNATH GARGCNYTNGCNAGYTGYYTNMGNTAYCARGARACNAARATHACNTCNTCNGARGGNAAY AARGAYGTNGAYTGGGGNAGYGARATGMGNMGNGCNGCNTTYYTNGCNTTYGCNTCNATH AGYGCNAAYGAYGARGARATHMGNGCNAARGTNATHAARAARGAYGGNGTNATHAARCAR ATHCARACNTCNYTNATGAGYAGYAGYGAYGGNGARGTNGCNGCNAGYYTNMGNTGYYTN CARTCNYTNACNMGNTCNGTNCARCARATHMGNACNGARYTNCAYGAYAAYGCNGTNTGG AARCCNYTNYTNGARAARGTNMGNTCNGGNAAYAARGARATHATG--------------- ATHYTNGCNATGTCNTGYYTNTGYAAYYTNGTNYTNGARTTYTCNCCNAGYAARGARGCN YTNGTNGARAAYCAYGCNGTNGAYGTNYTNTGYAGYYTNTCNMGNAAYGAYGAYAAYATH GTNMGNYTNAAYGCNACNTGGGGNATHATGTCNATGTCNTAYTGYGCNTCNGARGAYYTN MGNACNAAYATHATHAAYAARYTNGGNACNACNACNYTNGTNMGNMGNATHCARGAYCCN GTNYTNYTNATHMGNGARAARGCNYTNTGYATHGTNMGNAAYYTNYTNGCNGGNAARATG ACNATHGAYAGYACNGTNAARCARYTNGGNAAYGARGTNATHGARGCNGTNTTYAARACN YTNTCNGAYCAYGAYATGCCNTCNAAYATHATHACNCARGCNYTNTGYGCNYTNAGYAAY ATGGCNGAYGGNCCNTCNTGYAARGCNTAYATGATHGCNAARACNGAYGARATHAAYGCN GTNGTNAARTAYYTNCARTAYCCNGAYAARGAYYTNCARYTNCCNGCNATHCARTTYGTN AGYAAYYTNGTNGAYACNAGYGAYGAY------------------------GGNTCNTAY CARMGNATGYTNCARYTNAARACNYTNGGNGTNCARACNYTNYTNGARAGYYTNGTNGGN ACNGGNYTNGARGARGTNGARYTNMGNGCNCARCARGCNYTNAARTAYTTYGCN------ ------------------------------------------------------------ ---------------------------GGNAARGAYGAYGGNYTNYTNMGNACNATGAAY ACNGARAARYTNYTNAARACNYTNCCNGTNYTNCARCARCARYTNGAYGCNYTNYTNGAR TTYGAYTGYACNCCNAAYGARYTNACNAAYGGNGTNATHACNGCNTGYTTYATGYTNYTN TTYAARGAYYTNATHMGNYTNTTYGCNTGYTAYAAYGAYGGNATHATHAAYYTNYTNGAR AARTAYTTYGAYATGAAYAARAARCARTGYAARGAYGCNYTNGAYYTNTAYAARMGNTTY YTNGTNMGNATGGAYAARGTNTCNGARTTYYTNAARGTNGCNGARAAYATGGGNATHGAY AARGGNGAYATHCCNGAYYTNGCNAARGCNCCNGCNAGYYTNYTNGAYGCNYTNGARCAR CAYYTNGCNTCNYTNGARGGNAARAARTCN---GCNACNACNCCNACNGGNTCNAGYAAR CCNTCNGGNTTYACNACNGCNYTNAAYAAYATGTCNAGYAAYACNTTYAAYGTNAGYGAR GCNGARAARAARMGNATHYTNGARGARGARAAYCARCARYTNCARMGNCAYAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR AGYMGNAARMGNYTNMGNCCNTGGYTNAARCAYACNGAYGCNGARCAYTTYGGNYTNAAR TGGGTNGAYAARGARGARGGNATHTTYMGNATHCCNTGGATHCAYMGNAGYAGYMGNAGY TGGAAYAARGAYCAYTGYCARGTNTTYAARGARTGGGCNAARTTYACNAAYMGNTAYAAY GAYGGNGAYGAYGARGAYTAYCCNGGNTGGAARACNMGNYTNMGNACNGCNYTNACNAAR YTN--------------------------------------------------------- ---------------ATGGCNGGNMGNCCNAARTCNGGNATHACNGCNGGNACNGAYGTN AAYYTNGAYTTYYTNTCNAARGARGARAARGARGCNYTNYTNTCNAARAARATGGAYATG ATHMGNCARCARAAYAARATGATHAAYGARMGNCAYGARYTNATHGARGCNGAYMGNMGN AARGCNGARGARTCNGGNAAYGCNGTNAARGCNATGGAYAGYAARACNYTNCCNGCNGAR GGNGCNCCN---ATHAARCCNMGNGGNMGNGGNMGNGGNCARAGYCARGGNCARGGNTCN CAYMGNGAYGCNCARMGNCCNAGYAARGAYMGNCCNMGNTCNCAYGGNGAYACNTCNTCN TAYGARCCNATHGTNGAYGTNAGYGAYTTYACNGTNCAYMGNAGYMGNAAYAAYAAYMGN GGNAGYAAYAARGGNGGNCARCARCARTAYCAYCARCAYTAYCAYCAYCARGAYMGNGAY GGNCCNGTNTCNACNCCNAARAAYMGNMGNAARCCNCAY--------------------- ------------------------------------------------------------ ---------------------------CAYCARAARGAYGARGGNTAYAAYGCN------ ------------------------------GGNGGNCAYGCNMGNTCNAAYMGNMGN--- ------------------------------------------------------------ ---------TCNGAYCCNAAYCCNCCNCCNGAYCCNACNTTYAAYCCNYTNGCNGAYTGG MGNMGN---------------GARMGNGGNTCN------------GAYGARMGNTCNGAY CAYAARMGNCAYCCNMGNAAYTAYGGNGGNGGNGCNGAYYTNGCNAARGTNAARGAYAAY ATGAARACNATGMGNGARMGNGARAARGARMGNCCNGTNTCNTCNMGNAAYYTNGARATG GTNATGACNGGNMGNGARMGNAARAAYCAYGARCARTGGAARCARGARMGNGARMGNTAY GAYAAYGARMGNGTNCARMGNCARATGGCNGAYAGYGGNTCNTGGAARMGNGARTGGGAY CAYGAYAARGTNGTNATGGARTTYGAYGAY------CAYCAYCAYAGYMGNATGGARCCN GCNAARMGNCCNGCNGGNMGNATHGGNAGYGGNMGNTTYGAYMGNGGNGAYMGNGARGAY MGNCCNAARGCNGTNGTNMGNGAYGGNAARGGNGGN------------------------ ---------------------------------------------------------CCN TCNCCNCARGTNCARTCNCARCARAGYCAYCAYCAYCAYCAYCAY---CAYCCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNAARGTNGTNGAYYTNATHGCNMGN GTNTCNMGNCCNGTNGGNAARGARMGNACNCARGGNTCNGGNGTNAARAAYTTYAARMGN TTYAARAARACNGTNCAYTGYGGNAGYAAYMGNYTNCCNACNATHATHGGNGGNMGNGAY YTNGARCCNCAYAARAAYACNMGNYTNAAYCAYATGGAYGAYYTNYTNGARGARGCNGTN ACNGCNGGNAAYMGNGTNMGNGARAGYGGNATGTTYAGYTGGGCNATHGARMGNTGYCCN TCNAAYATHACNAGYYTNTAYTCNAGYGTNTTYGARGGNMGNTGYTAYCAYTTYGTNATH TAYAARGCNYTNGARTAYGARGAYGCNMGNTCNTTYTGYAAYGGNATGGGNGGNGAYYTN GCNGTNGTNAARTCNAARMGNGTNAAYGAYTTYATHTAYGCNMGNYTNAARTAYGGNTAY GAYGGNAAYGCNTGGATHGGNYTNAAYGAYGCNAAYGCNGARGARGCNTAYACNTGGGTN GAYGGNTCNYTNATHGAYGCNAAYGGNCCNMGNCCNGARCCNGTNTAYYTNMGNMGNGAR AARCARCARCCNCCNACNYTNACNGCNTCNAARCAYCCNCAYGGNTCNAGYCCNACNACN GGNAGYCAYCCNCAYACNGGNCARGCNMGNCCNYTNTTYTAYGGNAAYGAYAAYAGYAGY GTNAAYMGNCARTCNMGNACNCARACNACNMGNCCNGAYCCNATHCCNGGNCARCCNTAY GCNGGNGCNCCNGCNCARMGNGTNGGNAGYGCNCCNYTNMGNAARATG---ACNAAYCAR GGNACNATHMGNACNGGNCCNGGNAAYMGNTCNAAYAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CAYGTNYTNCCNYTNGCNYTNCARATGTAYGGNTGYMGNGTNATHCAR AARGCNYTNGARTCNATHCCNTCNGAYATGCARGTNGARATHGTNAARGARYTNGAYGGN CAYGTNYTNAARTGYGTNAARGAYCARAAYGGNAAYCAYGTNGTNCARAARTGYATHGAR TGYGTNGARCCNGARTAYYTNCARTTYATHATHGAYGCNTTYAARGGNCARGTNTAYAAY YTNTCNACNCAYCCNTAYGGNTGYMGNGTNATHCARMGNATHYTNGARCAYTGYACNGTN GARCARACNCARCCNGTNYTNGAYGARYTNCAYGARAAYACNGARMGNYTNGTNATGGAY CARTAYGGNAAYTAYGTNATH------------------------------ATGAGYACN TCNGTNGGNACNATGMGNGCNGGNGCNACNAARYTNCCNGGNCCNAAYGARAARACNGCN AARGGNGAYATGATHACNTCNTCNCARTCNGGNACNGCNGCNAARACNGAYGGNCAYTCN AARAARATGCARCCNACNCARGARCARYTNMGNYTNGCNCARATGATGAGYATHAAYCAR ACNGAYGCNGAYCCNAAYACNGTNMGNCARYTNATGGAYATGACNGGNAARAGYGARGAY GARGTNGTNATHGCNYTNCAYGAYGCNGGNAAYGAYGTNGARMGNGCNGTNATGTCNYTN YTNGARGGNGGNGARGARCARGAYGARTGGMGNGARTGYGGN------AARAARAARAAR AARAGYACNCARAARGARAAYACNAAY------AGYGARGAYCAYTCNGARGGNMGNAAY MGNGAYMGNGGN---------------------------GAYAAYCARGAYYTNCCNCCN MGNMGNGGNMGNMGNAAYGGNGTNCCNCCNCCNMGNYTNGCNMGNGGNMGNGGNMGNGAY MGNGGNAAYTTYGGNGAYMGNGAYMGNGARMGNAAYAAYGCNTCNGCNGARGAYTGGGAY AAYGAYAAR---GAR------------------GAYMGNGGNCCNMGN------GGNGAY MGNGGNMGNTTYMGNGGNMGNGGNGGNTTYAGYGGNMGNMGNCCNACNGGNGCNYTNAGY GGNGGNMGNGGNGGNMGNTTYAAYAAY------GAYMGNGAYAAYMGNGGNTTYAAYMGN CCNMGNMGNTTYGARAARATGAAYAAYTCNCARCCNYTNGAYGGNCCNGARCCNGARATH GAYACNTGGACNAAYGARACNGCNGARACNAAR---TCNAAYAARGAYACNGAYTGGAAY AGYTGGAAYGAYTCNTGGGTNAAYGARGARGAYCARTGGACNGGNACNYTNGARGARACN AARGTNTTYACNCCNTCNCAYGTNAARATGCCNGARGCNGARCCNGTNAGYAAYGARCCN CCNAGYTCNYTNGGNCARMGNYTNGAYGTNGGNAGYYTNTTYGARAAYGCNAARTTYACN AARGCNCCNGAYTAYAGYAARCCNAGYGGNGAYTCNTAYATHAAYCARTTYAAYCARGCN GCNACNGARTCNATHAARAAYACNATHGGNATHGGNAAYACNGCNMGNCCNCARATHCCN YTNTCN---------------CCNCCNGAYACNTCNGGNTCNYTNGGNYTNTCNAAYYTN GCNCARAARACNGCNCARGGNCARGGN---TCNGTNYTNCCNTCNYTNCARCCNTCNGTN CCNCARAAY------TCNYTNCCNCAYGCNATGGCNCARYTNTCNCARATHTCNCARCCN GTN------------------TCNCARCARTCNACNGGNATGTCNCARATG--------- ---------------------------GGNATGGGNTCNCCNCCNTCNGCNTCNGCNAAY CARGCN---CCNCARCARTCNMGNATHCCNGCNGTNGTNCARCARAGYATGCCNCARACN AGY---------------------------ATHAAYAAYATGCCNCARMGNCCNAARACN CARMGNTCNAARYTNCCNCCNCCNTCNAARATHCCNTCNACNGCNGTNGARATGCCNGGN CAYATHCCNMGNAAYCCNCARYTNGAYGTNCARTTYGGNYTNGAYTTYGGNTCNGARCCN TCNGTNCARTTYGGNTTYGGNGGNAGYGGNGAYAGYACNGCNGTNACNAGYTCNTAYTCN ACNGCNACNAAYGGN---ACNCCNGCNATHTCNAAYCAYYTNAAYCARGGNCAYATGACN CARTCNGCNGGNGAYGGNAAYTCNGTNAGYCCNATHATGCCNTCNCCNTCNGCNGGNTCN GCNAAYGTNCCNTCNGCNATHGARTCNCARGGNCCNAAYMGN---CARGGNGTNTTYCAY AAYTCNATGTAYCCNTCNACNCARCARCARACNGARAGYCARGCNYTNGARATHGAYCAR AAYAARGTNAAYGAYTCNATHCCNTTYYTNTCNTCNCARYTNGARMGNAARTCNAGYCCN ATGGCNTCN---CARMGNCCNGGNCARACNAAYCARAAYYTNACNTCNGGN------CCN TCNAGYAARAGYGAYTCNACNGGNGCNGTNGCNAAYAAYAGYTAYTCNGCNGCNAAYGGN TAY---TCNTCNTCNTAYCARAGYCAYTCNAARGGNTCNTCNATHTCN------CAYACN GCNACNTCNCARCCNTCNCARACNTCNTCNTAYCAYGGNCCNTAYCCNGTNAAYCARTCN TCNTAYCCNTCNACNGGNCARACNCCNTTYCCNGCNCCNCCNAAYGCNGCNCCNTTY--- CCNTCNGCNCARCCNTCNCARTTYAGYTCNTCNAAYTCN------TCNCARAAYCARTTY TCNTCNGGNCARAAYCARTAYTCNGTNGGNACNTCNACNYTNTCNCAY------CARAAY AAYCARTTYCCNTCNAGYGGNCARAAYAAYTAYGGNAGY---GGNTCNTCNCARTAYTCN GGNTAYCARAAYAAYAGYTCNTTYCCNCCNCAYCCNCARTCNCARACNAAYTTYCCNTCN ACNCARAAYGGNGGNACNGGNGCNGTNYTNTAYCCNACNTCNACNCARTCNGGNGTNGCN TCNTAYACNACNCARTCNAGYTCNTAYCARTCNCCNTCNGCNGGNTCNTAYCAYTCNTCN MGNGAYTCNGCNACNAAYATGGCNGTNAGYACNCARTCNACNAGYGGNATGGCNTTYCCN AGYCARCCNCARAAYTCNAAYATGAARCCNGTNACNACNCARAGYAGYTCNAGYTAYAAY TCNCARAGYTAYACNGCN---CCNACNCCNYTNCARCCNTCNTCNYTNGCNAAYAARYTN GGNGARAGYYTNTCNAARATHTCNATGAARGAYTCNTCNTCNGTNYTNGAYAAYCAYCAR TCNGCNCARTAYGARCAYACNCCNTCNCCNGCNAGYGTNCCNACNAGYGTNAGYYTNCCN TCNGCNTCNAGYTCNTCNTCNYTNTCNACNGGNACNAAYGCNYTNTCNTCNGCNTCNACN GTNACNTCNGTNTCNCCNGCNTCNMGNGTNGCNTCNATGCCNTCNGCNTCNGGNAARGCN CCNCCNAAYATHCCNCCNGGNGTNCCNYTNATGGGNCARTAYATHATGGGNCARAGYACN ATHCCNCCNTTYTAYAGYGTNCARCCNCCNYTNTAYGGNTAYGARGAYGTNCARYTNYTN CARCARMGNATGCCNATGCARACNGGNAGYTTYTAYGAYATGGGNGCNTTYCCNGCNGCN CCNGCNGGNTCNACNYTNCCNACNGGNMGNGAYCCNCARCCNCCNATHCCNAAYGTNCCN TTYTCNGGNACNTCNGAYACNAARYTNGCNMGNGTNGAYGCNCARAGYCCNAAYGCNTCN AGYCARCCNCARAGYGCNCAYTCNGCNACNCARCARCCNYTNYTNAAYTTYCAYTAYGGN TAYTAYTAYCCNTCNATGTTYCCNGGNGCNGCNGGNYTNCARTAYCCNACNACNGTNTAY CCNATHCCNCCNGTNACNAAYGCNGCNGCNCAYCARGGNACNACNGCNACNACNCARTTY CARAARACNTTYCCNTCNCAYGTNTAYACNACNAARGGNTAYGARGARGTNAAYCARGTN CARGAYTTYTCNAARACNGGNTAYGGNAGYTCNCARAGYTGYGGNAARGCNTCNGGNACN MGNATGTCNACNMGNTCNGGNACNAGYGARATGACNCCNAAYGCNTAYAGYAARTCNCAY GGNCARGCNGGNTAYGAYAARCARGGNTAYCAYGGNGGNACNCCNCCNCCNTTYAAYYTN CCNYTNGCNTCNGGNACNCARACNGGNCCNATGGGNGCNCCNACNACNCCNTAYGGNGCN CCNTTYYTNCCNGTNATGGCNGCNCAYCARCCNCAYTCNCARATGATGCAYCAYCCNATH CARCARGAYAGYAAYACNACNAGYTCNMGNGGNYTNAAYCCNGCNGGNGGNCARGGNAAR TCNGGNGCNGCNAARTCNTTYGGN------CCNCCNTAYTGGAAYAAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGGNGTNYTNGAY ATGYTNAAYCCNGCNYTNGTNYTNAARYTNMGNYTNGTNGTNTAYGGNATHYTNATHTTY TTYTCNTTYTTYATHTTYGTNGGNACNGCN------------------------GTNATG TGYCCNYTNTAYGTNGAYTAYAGYGCNMGNGGNTTYGAYGCNGGNCCNGAYTCNAAYTGY GGNTAYCCNATGGCNATHTCNATHATGTTYCARYTNYTNTAYYTNYTNTTYMGNATHGGN ACNYTNGTNYTNGTNYTNYTNGGNAARTTYACNGCNGAYATGGTNYTNTTYACNGAYYTN GCNGARTTYGTNTAYGTNGTNGTNGAYYTNTCNGCNTTYTTYYTNATHTTYATHGCNGCN TGYATHYTNTCNGCNGGNACNAAYCAYACNTGYGAYGTNATHGAYTGYGGNAGYAGYMGN TGGGAYGAYGTNATGTCNGCNTCNAARGCNGCNCARGCNGGNGCNTGGATHAGYACNTTY YTNTGGYTNTTYATHGGNATHTGYGGNTTYATHACNYTNTGGMGNGCNGGNAARATHCCN TTYYTNCCNGGNGGNGGNGCNGCNAARTCNGAYCCNAAYACNACNGGNCCNGAYACNAAY CARCCNCCNATHGARACNCCNCCNTAYAAYCCNGAYGARCCNCCNAARTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TTYAARAARMGNATHCARMGNMGNYTNTAYCAYGCNTGYACNAGYGAYTGYGAYAGYGAY AGYGAYATGGAYGGNYTNAGYACNTCNTCNYTNCCNYTNACNGARACNTGYATGGARTAY TTYCARGAYAGYTTYCCNGGNTCNGARGGNYTNGGNMGNYTNGAYATGCCNATGGCNGCN ACNGTNACNAARCAYAAYCARGTNTCNCCNTGYTCNGTNGTNYTNTCNATGATGTAYGCN AARMGNYTNMGNCARMGNAAYAARYTNTAYYTNCARTCNATGTCNTCNACNGAYGTNTTY TTYATHTCNATGATGATGGCNAGYAARTAYYTNTAYGAYGARGGNGTNGARGARGARGTN TAYAAYGAYGARTGGGCNGCNAGYGTNGGNCAYGARACNGAYGAYGTNAAYCARATGGAR ATGGAYTTYYTNAARGARATGGAYTGGCAYYTNTTYGCNAARCAYGARGAYTTYGAYAAY GCNYTNACNGCNGTNGARMGNMGNYTNGCNYTNAARGARGGNGTNAARMGNGGNTGGTTY ACNTAYACNGARATGGCNGTNYTNYTNGAYTGGGAYCCNGTNTGYAAYYTNTGGAAYCAR GTNGGNATGGAYTGYACNAARATGGTNTCNYTNYTNTCNGCNGTNTAYGTNGCNAGYYTN GTNAGYATGATGGGNTCNGCNGCNYTNGCNYTNCARYTNTCNGGNCCNGTNGCNTCNGCN ACNGTNGCNGCNATH--------------------------------------------- ---MGNTGYTGYCCNMGNTCNTGGAAYTAYCARTGYMGNAGYAGYAAYGTNMGNYTNCCN TGYTTYTCNCAYTAYTAYGGNGGNGTNMGNGARTGGTGYTGYCCNATHTGGCCNTCN--- ---GTNTTYGTNAARMGNTGYATGTGYAGYCARTGYGCNGTNYTNACNTCNACNTGYGCN CAYGARGGNMGNTGYCARMGNMGNTAYTCNMGNMGNAGYTTYYTNGCNGTNTGYTAYMGN AAYAAY---CARTGGGGNAAYYTNMGNTAYATHACNAARTAYYTNCCNTCNAGYTGYTAY TGYMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGTNTGYGTN CCNTGYTTYYTNATHCCNATHATHYTNTGGATHTTYCAYAARTTYATHCARCCNTGGYTN TCNMGNATHTGGAGYGGNTCNGARAAYTAYGTNACNAGYAAYYTNACNTGYCCNATGCCN CARAARAARAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CAYCCNGAYGGNAARGARATGCARATHAAYYTNACNGGNTTYYTNAAY GGNAARAAYGCNMGNGTNTTYGTNTCNGARYTNTGGACNCAYYTNTGYAGYGCNCARGAR AAYGTNACNGGNATHCCNAAYGARTTYYTNGARCARAARAARAAYGARATHAARCARMGN CARGARGARCARGARMGNYTNCARGARCARYTNAARYTNAARGARGARCARATHAARGAR CARYTNTCNMGNGARMGNAARGARYTNGARAARAARGAYYTNAAYAAYYTNTCNCCNGAY MGNCCNAARCCNATH---------------------GARACNAAYGGNATHAARCCNYTN ATGGAYGTNGARGAYAGYGCNAAY------------YTNAARGCNGARATGAARTCNGAR CCN------------------------AARATHGAYGCNGCNGGNGARCCNCAYGGNGAR GGNGARGTNAARAARGAYCARAARGARAARGARMGNGAYMGNACNCCNGAYAARMGN--- ------------MGNGARAAYMGNGAYMGNGAYMGNGAYMGNGAYMGNMGNMGN------ CAYTCNMGNTCNCCNGAYMGN---CAYMGNCCN--------------------------- MGNTCNMGNACNCCNGAYMGNCAYMGNMGNGARMGNGAYMGNMGNCCNMGNMGNTAYTCN CCNCCNMGNMGNMGNTCNMGNTCNCCNMGNMGNMGNTCNCCNCCNCCNAARMGNMGNTCN CCNCCNMGNMGNTCNCCNTCNCCN---------CAYAARAARMGNTCNCCNCCNAARGCN GARGCNGCNAARMGNGAY---------MGNTCNAGYAGYGGNAGYAGYTCNAGYGGNTCN GARGAYGAR---------TCNGGNAARGAY------TCNTCNCCNGARAARAGYGGNGTN CARCARMGNMGNAAYTAYMGNAARCAYGAYGAYGAYAGYGGNAARGARTCNTCNTCNTCN TCNGAYGGNGARGCNGCNAARGAYAARMGNMGNCCNTCNCCNCCNMGNGAYMGNMGNAAY GCNMGNAGYCCNTCNCCNMGNMGNMGNMGNTCNCCNCCNCCNTAY--------------- ------MGNMGNCCNAGYCCNMGNMGNCARAGYCCNCCNMGNMGNMGNTTYCCNTCNCCN CCNMGNMGNMGNATGAGYCCNGTNCCNCAYMGNMGNAGYCCNTCNCCNMGNMGNMGNTCN CCNGGNMGNYTNTCN---CCNMGNMGNMGNAGYCCNCCNMGNTAYMGNMGNCARGCNTCN ATGTCNCCNMGNMGNMGNMGNATGTCNGCNTCNCCNYTNMGNMGN---CCNCCNTCNCCN TTYCARGGNMGNMGNMGNMGNCCNTCNMGNTCNCCNTCNGAYTCNCCNGTNAARMGNMGN MGNCCNTCNCCNCCNCCNTCNCCNCCNGCNAARTCNAARAARAARMGNGTNTCNCCNCCN CCNTCNGARTCNGARGAY------TCNTCNAGYTCNGAYGAYTCNTCNCCNTCNCCNCCN CCNGCNTCNAARMGNCCNTCNAARGGNAARGARCARAAR---------CCNCCNAARMGN CCNCCNCCN---------CCNACNAARCARACNAARCCNTCNAGYGAYGAYAGYTCNTCN TCNGGNTCNGARGAYAGYGAYGARGAYTCNGAYTCNGAYAARCCNTCNTCNCCNCCNCCN CCNMGNCARAARCARAARCARACNTCNCCNTCN---------------AAYAARMGNCCN TCNCAYGGNTCNMGNTCNMGNTCNMGNTCNCCNGTNAAYMGNMGNGARMGNMGNCCNAGY CCNCCNCCNMGNAARMGNACNTCNCAYTCNMGNTCNCCNGTNCAYMGNMGNMGNCCNGCN TCNCCNCCNCAYMGNMGNGGNTCNMGNTCNCCNCARGCNMGNMGNYTNCCNCCNMGNGAY GARTCNTCNAGYTCNMGNMGNCARMGNMGNGAYACNGAYCCNTCN---GAYCAYGARYTN GGNMGNMGNGAYMGN---------------------MGNCCNAGYCCNCCNMGNAARMGN CARGTNMGNTCNCCNTCNCCNAAYMGNGARMGNGAYGGNGGNAGYAARGAYCAYMGNGGN MGNMGNTCNCCNCCNCARCCNGARMGNCAYMGNGARGCNCCNGAYMGNCARGAYAAR--- ------------MGNAARGARAARMGNCCNCCN---------------TCNTCNGAYAGY AGYAGYGAYAGYAGYTCNGARGARGAYGARAARGAYYTNAARAAYAARTCNAARGCNGCN CCNATGAARCCNTCNAGYGGNMGNCCNGCNMGNMGNTCNTCNCCNGGNGTNGCNGCNAAR MGN--------------------------------------------------------- ---------AARCAYTCNGCNAGYCCNTCNCCNCCNMGNGCNAARGTNTCNMGNMGNGAY GCNAARGAY------GAYGAYAARCARMGNAGYGAYAARCCN------------------ ------MGNCAYMGNTCNGTNAGYCCNAAYMGNCAYGTNACNTCNCCN------------ ---------------------------------------CCNAAYGGNAARGGNTCNCCN CCNCCNTCNACNAARCCNAARAARGAYAARCCNGTNGARTCNGCNAGYAAYAGYGAYTCN GARGGNTCNGAYTCNGAYAAYGCNTCNAARAARAARAARAARAARAARGAYAARAARCAY AARAARCAYAARAARCAYAARAARCAYAARCAYAARAARGARGTNCCN---------GAR AARGGNGARGAYYTNGARCARMGNYTNMGNGARAARGCNYTNATGTCNYTNYTNCAYMGN AARAARAARCARACNTCNCARGAYCCNGAYAAYGAYTCNGAYAGYGGNAGYAGYAGYGGN GARGARACN--------------------------------------------------- ---------------------------------------YTNGAYYTNGARGGNGCNGCN TAYCCNYTNTTYGCNAAYMGNMGNACNMGNAARGARACNTTYYTNTCNTGGGAYCCNACN CAYAGYCARAARCCNGARGAYYTNGTNAAYYTNGGNTTYTTYTAYGCNGGNTAYTCNGAY TGYGCNMGNTGYTTYTAYTGYGGNYTNGGNYTNAARTAYTGGMGNCCNAAYGAYGAYGCN GCNTAYCARCAYGCNMGNTTYMGNCCNCARTGYAARTAYAAYCARTTYGTNAARGGNCAR GAYTTYATHGAYCAYGTNCARMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ACNATHGCNMGNMGNTGYMGNCAYAARAARMGNAARYTNAAYTTYTTYGTNGTNGARTCN GCNYTNGARYTNTAYGCNMGNGAYATGYTNYTNATGATGGTNGTNYTNGARYTNCARCAR AAYATGGGNYTNCARGARAARACNGARGTNTTYYTNGARATHCAYGGNAAYACNYTNYTN MGNCARCARACNAGYGAYTAYATHCARAARATGTCNCAYCARYTNATHMGNATGGTNACN GAYTTYGAYTAYATGGARAARAARATHCCNATHTTYGAYYTNAAYCARYTNAARTAYAAR GARMGNGAYTTYYTNGARGGNGTNYTNAARYTNTGGMGNAAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNYTNYTNYTNTCNTTYTTYATHYTNTCNATHTCNATHACNGTNGCNATHAGY MGNCCNMGNGGNGTNTCNYTNGARAARGCNTCNTTYTAYCARYTNGAYACNGARTTYMGN TGYYTNACNAGYGGNAARGTNYTNCCNGCNGAYCAYGTNAAYGAYGAYTAYTGYGAYTGY GARGAYGGNTCNGAYGARCCNGGNACNTCNGCNTGYTCNAAYGGNYTNTTYTAYTGYGAR AAYMGNCCNTAYAARGGNCAYTAYATHAARTCNTCNMGNGTNAAYGAYGGNATHTGYGAY TGYTGYGAYGGNTCNGAYGARTTYGAYGGNATHATHGCNTGYTCNAAYACNTGYGTNGAR AARTAYGARCARGARMGNGCNMGNCARGARGTNYTNMGNCARCARCARTCNGARGGNTAY AARGTNAARCARGARTAYATGCARCARGGNAARMGNGCNAARGAYGARAARMGNTCNAAR YTNAGYGARYTNGARMGNGARAARGARGTNYTNACNMGNGARAARGARACNGCNGARACN GCNAARAAYGARGCNGARGARCCNGARAARGCNGCNATHGARGARCAYAARAARGCNTGG GARYTNGTNAARGARGARMGNCARAARGCNAARGAYGCNGTNAARGCNGCNCAYGCNTTY TCNACNYTNGAYGTNAAYAAYGAYGARAAYGTNGAYTAYCCNGARYTNATGAARCAYAAR GARTTYGAYATHGAYTCNGAYGGNACNGTNAGYGARGARGARGCNAARGARTAYYTNGAR GAYAAYGARCARGTNGAYYTNACNGTNTTYACNGARAARATHTGGCCNAAYATHAARGAR ATHTAYAAR------ATHGCNCARGARGARAARCCNGARGGNCARGTNCCNGARGARCCN ACNGAYCARGARCARGARGAYGAY---------AARGARAARGAYCCNGAYGARGARGAR GARGARGAYGAYGAY--------------------------------------------- ---------------GARGARAARGARCCNGARTAYAAYGARGARACNAARMGNYTNATH GAYGTNGCNGAYCARACNMGNACNAARTTYAAYGARGCNGARMGNAARGTNAARGAYGCN GARMGNGARATHGAYGAYACNAARAARTAYYTNGARATHGAYTTYGGNCCNAAYGARGAR TTYGCNTTYYTNAARGGNCARTGYTTYGARTAYACNGAYMGNGARTAYACNTAYMGNYTN TGYCCNTTYGAYAARAGYACNCARAARAAYAARAAYGGNGGNATHGARACNTCNYTNGGN ACNTGGGGNAARTGGCAYGGNCCNGAYGAYGAYAARTAYGAYACNATGAARTAYGARAAY GGNCARGGNTGYTGGAAYGGNCCNTCNMGNTCNACNCAYGTNAAYYTNCAYTGYGGNTCN ACNAAYACNYTNACNAGYGCNTCNGARCCNAGYMGNTGYGARTAYCARTTYGARTTYACN ACNCCNGCNMGNTGYGCNGARCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GGNGARTAYGTNGTNTGYTAYGGNACNTCNCAYGGN AAYTTYGCNTAYGARCAYCAYAAYTCNGGNGTNYTNGTNAGYCAYYTNAARAAYATHYTN CARTCNMGNYTNGGNGTNGARGAYGTNTTYAARCAYYTNMGNACNGARYTNAARAAYGAY CCNATHYTNAARTTYGAYTCNGAYGGNAAYMGNGTNAARCARGCNCCNGARATHMGNACN ACNYTNTCNGARGCNCARMGNTCNTTYCAYGAYAARATHGAYTCNAARGGNCAYACNCAR GARTTYACNGARMGNCARATGATHTGGGARMGNGCNCAYMGNCARCCNAGYTCNMGNGAR ATHACNGTNCCNTTYCCNGAYTTYAAYGTNAAYGTNMGNYTNGAYTTYCARACNGARTTY TCNAAYGCNYTNACNATHTTYTGYTCNGTNGTNAAYGCNGGNMGNTCNAARATHTGYAAR GCNMGNATHACNGARATHCCNTAYGAYYTNMGNGARAARGCNAARGTNTAYATHYTNCAR GARGGNACNGARACNACNYTNTGYAARAAYTAYYTNCCNYTNCARGAYATHCARMGNYTN AARGCNGARATGYTNATHAARYTNTCNGTNACNTGYYTNCAYGAYGGNACNGARATHACN YTNCAYGCNGTN---GARAAYYTNGGNYTNCCNYTNGTNTCNCAYYTNMGNYTNTGGMGN GARACNCCNGAYYTNACNMGNTGYYTNGARGCNGARGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNAAYAAYCCNATHCARYTNMGNCAYATHGTNATGATGATGYTNGCN GCNTGGYTNTGGGGNGCNTTYTGYGCNACNATHACNGTNACNGGNYTNAAYACNGTNAGY TAYAARCCNGGNACNTCNCARTGYGGNCCNGAYTAYCCNGARGARYTNMGNGGNTAYYTN TTYCAYGGNATHGTNCARGTNACNGTNATHATHYTNCCNTTYTTYATHYTNYTNTTYTGY TAYATHMGNATGTTYMGNGARATHCARMGNCAYTCNGARMGNYTNMGNAAYAAYACNACN GTNGARGARGAYTTYATHYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARCCNYTNTTYGAR AAYGGNCARYTNTCNTTYYTNGGNCAYGAYGTNGARTCNATHCCNMGNAAYYTNATHGAR GAYTAYTGYAAYATHTCNCAYMGNYTNGAYYTNAGYTTYAAYMGNYTNCARTCNYTNAAR GGNYTNGARCAYTTYAARTTYYTNAARGARYTNATHYTNGAYAAYAAYGAYYTNGAYGAY TCNGTNTAYTTYCCNCCNYTNMGNGARYTNCARACNYTNACNYTNAAYAARAAYMGNYTN AARGAYYTNACNTCNYTNATGGARCARTTYCAYGCNMGNTAYCCNAAYYTNACNTAYYTN AGYYTNYTNGGNAAYCARGCNTGYCCNAAYCARYTNTCNTCNYTNGAYAARGAYGAYGAR GAYTAYCARMGNTAYMGNTAYTTYGTNATHTAYAARYTNCARAARYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARYTNACNGAYATHATHTTYATHAGYACNGGNYTNTAYGAR CARACNYTNAAYATHGARAGYMGNGAYAARAGYMGNCARAARCARMGNYTNTGGGTNGAY CCNAGY---------GAYTCNGAYACNGCNGCN---------TAYAAYGARACNCARGGN TTYCARCARGGNCCNGGNYTNAARCCNGGNAARAARACNAARGGNMGNGTNAARATHAAR ATGGARTTYATHGARAAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------TCNCAYCARAAR TAYGTNCCNCARACNGCNCARTAYGTNAARGCNTGYAARGARACNGARGTNTCNGAYTCN GTNMGNAARGARATHTCNGTNYTNMGNAAYGARGTNGARAARYTNGARCARGARYTNAAR CARATHCARATHAAYAAYYTNAARAARYTNCARAGYATHACNGARCARGAYAGYAGYTCN ATHTGYATHYTNCCNMGNCAYTTYAARCARTTYYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GCNCCNGCNGARTCNTTYCARGGNATHTTY ACNGCNGGNATHCCNMGNAAYATHTGGTTYGGNGAYAGYGTNCAYYTNTCNTTYTCNACN GCNTGGMGNAGYTAYACNACNGTNATHGTNGTNAAYACNGAYACNGGNGAYATHCARAGY GTN---AARCAYYTNAARGGNATGAGYATGTCNGTNYTNAGYGTNAAYAARAGYTGYATH YTNATGTCNTCNACNTCNATGAAYACNCCNCCNTAYYTNYTNYTNGCNGAYTTYGARGAR ATGGGNAARCCNGARTCNGCNMGNTGGATHGCNCCNGAYGGNATHMGNAARAARYTNGAY TGGYTN---TCNTGGGARGTNYTNGCNCAYAARCCNACNGGNAAYMGNGTNAGYCCNATH AAYGCNAAYYTNGAYTAYGARAGYATHYTNTGYATGCCN---CARAARGAYAARGAYMGN CARCCNCCNYTNATHGTNTTYGTNCAYGGNGGNCCNCAYGTNGCNTTYGAYTCNTCNTAY AAYCCNATGACNAAYTTYTTYTGYYTNTGYGGNTAYGCNGTNYTNATGGTNAAYTAYMGN GGNTCNTGGGGNTTYGGNCARGAYTGYATHGARTCNYTNYTNGGNAAYGTNGGNGAYATG GAYGTNAARGAYGTNGARAGYGCNATGCARTCNGTNYTNTCNMGN------GTNGAYAGY GAYMGNGTNTTYATGGCNGGNGGNTCNCAYGGNGGNTTYYTNTCNACNCAYYTNATHGGN CARTAYCCNAAYACN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNTTYATGYTNGCNGTNAGYTGYGCNTCNGARGTNCCNATGTTYCARYTN GCNGCNGCNATHATHCAYAARATHGGNYTNATHCCNTGYYTNTAYYTNGCNYTNTTYTGY TTYTGYYTNMGNYTNYTNGCNTAYTCNYTNYTNGTNGARCCNTGGTTYGTNYTNYTNATH GARCCNATHCAYGGNGTNACNTAYGCNYTNATGTAYGCNGCNGCNGCNTCNTAYGCNAGY GTNYTNGCNCCNCCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TAYATHTAYCARGGNGAY ATHTAYGCNGTNCCNGAYAAR---CARGTNACNACNCCNMGNGAYGAYACNGARAAYCCN ATHATHTCNMGNATGAARGARATGGTNGTNGARAARACNMGNACN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CARYTNCCNACN---TCNTTYGTNGAYTTYCARACNACN TCNTTYGGNGAYGARYTNCCNACNGTNAAYTGYGAYYTNGCNGAYYTNAAYATHTCNACN AAYGAYTTYGAYCARYTNYTNYTNCARAGYYTNAARGAYGTNCCNYTNTCNYTNGAY--- ------AAYYTNGTNGGNACNGTNGAYAAYAGYGCNGCNATHGCNACNCARYTNGARTTY AAYATHYTN------------------------TCNTTYTTYCARAGYYTNCAYGGNCCN GCNCCNGTN---CCNATHTCNTCNMGNGCNTCNTCNGCNGGNAGYMGNGGNGAYGGNGAY GCNACNCCNCCNTTYTCNGGNGGNAGYACNCCNCARGGNYTNTCNMGNGCNCCNTCNCCN GCNTGGAGYGARAGYAGYGGNAAYATGAGYACNAGYAGYGTNTCNGGNCARTCNTGYCCN MGNAARATGAGYGGNGGNGGNAAYAAYCCNYTNCCNMGNCAYAARMGNCCNTCNCAYMGN MGNGCNGARGTNAARMGNMGNGAYAARATHAARACNACNYTNGAYGARATHAARTCNAAY GTNCCNTCNYTNCARGAYAARGGNAARCCNAGYGARTCNGCNATHYTNTTYAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYTAYYTNCARTAYTAYCARTGGTAYGGN CAYYTNTCNGARGGNGTNCCNTCNTGGCCNATHTCNGGNATHTAYYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CCNGGNATG YTNGCNTTYYTNAAYMGNCARGAYACNTGYTAYACNCCNGARAARTTYTTYGAYMGNACN ATHAAYYTNGAYTAYTTYGGNTGYCCNGGNCCNGTNTAYATHAAYGTNATHMGNGCNYTN TGGGAYTTYGCNAARATHGTNYTNTTYYTNTTYTTYGTNYTNATHATHGTNYTNGCNTTY GGNGAYGCNTAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYAGYGTNMGNYTNMGNCCNACNGCNTCNTCNMGN CAYAARTCNCCNTCNCCNGGNTCNGAYAARGAYTCNGCNATHGGNAARAGYGGNMGNAGY AAYTAYAAYMGNCARTCNTCNTAYTCNTCNAGYAGYAAYAGYAARTCNTCNCCNTAYCAY CCNTCNCCNATHGGNMGNAAYGARTCNCARAGYTAYGAYACNGGNGARGAYTAYGAYATH AAYYTNGAYGGNCARGARGTNGTN------------------GARGARGGNGTNGGNAGY MGNYTNGARGAYGARGARCARGGNGGNMGNYTNTCNGCNYTNCCNCAYYTNAAYCARTCN YTNTCNGAYYTNCAYTTYMGNCARAGYYTNATGCARMGNATHCARGARTGGTCNAGYTTY GCNGARGARTAYAAYAARTCNATGTCNCCNACNCCNGARTGYTCNCCNATHMGNTTYGTN MGNMGNAGYMGNTCNYTNGAYMGNCAYYTNAGYGAYTCNTCNGTNATHGCNACNGARTCN GARATHCCNTCNTCNAARCCNYTNGARATHGARCCNGTNACNGARAARAAYYTNGARACN YTNGARTAYGARYTNCAYGAYATHCARGGNGARTTYGARTCNATHACNTCNAARYTNCAY GAYYTNATHGARCARCARGCNACNCCNACNATHACNCCNTCNCCNTCNCAYGCNCCNATG TCNTCNTCNTAYCCNGCNGCNTTYATHTCNMGNAARTCNTCNACNCCNTCNTTYACNTCN ACNTCNAAYCAYTCNCAYTCNTCNCCNTCNCCNAARMGNAGYAARAGYACNCCNTGYGTN AAYAGYTCNACNAAYYTNMGNAARATGAARACNAARTGGGARMGNGTNCCNGGNTCNGCN TGYTCNGAYTGYAGYMGNAGYTCNMGNGGNAGYAGYGTNGARTAYGTNTGGGAYATGGCN GAYTAYACNGCNAAYTCNACNAGYCCNGCNACNGGNMGNMGNGTNTCNYTNGGNGGNATH ACNTCNACNGAYYTNTGYGAYGTNTGYAAYATHAAYCCNCCNGTNTCNGTNATHGARTAY TGYCARCARGARTGGAARGGNGAYACNCCNMGNGCNTCNGTNATHMGNCARGGNTAYCAY CARATHCCNTCNYTNATHCARMGNGARMGNATGTGYGTNATHMGNGGNGAYAAYTAYTGY GCNYTNMGNAGYACNYTNTTYCARGTNYTNGTNGARGGNATHMGNATHGTNCCNAGYTCN TGGGGNATHATHGGNATHATGGAYMGNYTNCAYGAYCAYTTYGAYGAYCCNACNATHCAR ATGTCNGCNTGGAAYTTYGCNAAYMGNYTNCCNGGNCAYTGYAARGAYAARYTNGCNTCN ATHTCNAARTGYGCNYTNTCNYTNTAYGCNACNGTNGARGARGTNTGYAAYYTNCCNACN MGNGARGARMGNGARAARMGNACNATHAAYYTNTTYAAYGCNAGYTCNACNTTYGAYYTN GARYTNATGGARGGNGTNAARGTNATGATGYTNYTNCARYTNGTNTCNYTNMGNCARMGN ATHYTNGAYGGNGARGARGTNCCNATHTTYGGNCAYYTNYTNTTYGCNMGNGAYACNTCN GTNTCNGTNGCNGAYTTYATHAARAAYCAYYTNAAYAGYGTNGGNGAYTCNGGNGGNYTN GARCARGTNGARATGTGYYTNYTNGGNTAYACNYTNGGNGTNAGYATHMGNGTNYTNMGN YTNTCNCARGCNGGNCARGARGAYTTYGARTGYTGYTTYCCNGAYGAYATGCCNTCNGAY ACNCCNCARGTNGTNYTNYTNGCNGARGAYGAYMGNCAYTAYAAYGTNCCNYTNCCNATG GCNGARAGYGTNGAYGGNMGNGTNATHTTYGTNGGNYTNCCNAAYGGNYTNGCNGCNATG GAYGCNTTYTCNCARTTYCCNYTNCAYAARTGGGARGARGAYCAYGCNGARATHACNAGY ATHAARACNTAYYTNATHTCNCCNGARTAYCAYYTNATHTCNACNGTNGAYGAYATGGGN ACNGCNMGNATHTTYYTNTTYGCNTTYGAYTAYATHTTYTTYGTNAARGCNYTNAAYGAR AAYAGYCCNGARGGNACNTCNAARATHYTNTGYCARAARTGYGARGCNTCNAGYGARGGN GAYTAYYTNGGNGTNTCNTTYGARAAYACNGGNAAYMGNGARATHTGGYTNGARGTNCAY AARYTNCCNGTNGARAAYTGGYTNAARGARYTNGARGCNATHCARAAYGTNATHGGNAAR AARAARGAYGARCARGARAARTCNCARGTNGARATHGCNGGNAAYGCNGGNGARGCNGAY CCNGGNTCNYTNCCNAARTCNATGGAYGAYACNAARAAYGAYGARCCNGCNGTNAAYATG GARTCN---GTNATHGARAARYTNGGNTCNAARTTYAGYCAYCCNTCNATHGTNTTYAAR GCNAARCCNCCNGCNAAYMGNTTYCCNGCNCCNAAYCCNTCNAGYAGYATHGGNTCNGCN GTNTCNAARGTNGAYCARGGNGAYGTNYTNGGNACNGGNACNAGYCAYGTNYTNAGYCCN GCNCAYYTNGARTCNMGNGAYGCNATGTTYAARCAYMGNTAYCARGGNYTNYTNGARTTY YTNCCNACNGARGARGARGARAAYCARATHTTYGTNAAYTTYCAYTTYACNAAYCCNAGY MGNATGATHCCNYTNGGNATGGAYCCNTCNTCNCCNCCNAAYAARCCNGTNTCNYTNTTY YTNTGGTGGTCNGGNACNCARCAYYTNTGYCAYTAYTCNYTNYTNAAR---ACNGGNAAR GAYATHGARTTYAARCCNGAYATHGTNTGGCCNTGYTCNGAYACNATHACNTGYTCNACN GTNAGYCCNTGYGGNTCNCAYGTNGCNGTNGGNATGGCNAAYGGNAAYYTNGCNYTNTGG GAYTAYCARATGGGNYTNCCNAARGCNGTNYTNACNGTNTGYGGNAAYGGNGGNGTNAAR GARYTNMGNTTYYTNGAYCCNACNYTNTTYCCNTTYGAYCCNCCNGARTAYCCNCCNTAY CCNGTNTCNTCNGCNACNTTYATHYTNGCNGARTAYTCNGAYGGNACNCARGCNYTNTTY GAYACNTGYGAYGGNAGYCARCARATHCCNMGNGTNGTNGCNTCNGTNCCNGARAAYGAY GAYGAYATHCARACNYTNATHCARATHATHCCNGAYYTNCCNGARYTNATGYTNTTYGTN AARAARAAYGGNTGYATGTAYATHAARGAYATHGGNACNGGNGCNTCNYTNTGYCARGTN GTNYTNCCNTCNACNCAYGCNATHCARACNCCNTGGAGYCCNATHTTYGCNYTNGGNGCN GGNAGYCARGTNYTNTAYYTNAARGGNGARGGNCARGAYGTNAGYGARGAYGGNGARGTN AGYGAYGTNTCNTGYYTNTTYAARTTYAAYYTNMGNGARTAYCCNATHYTNGCNGARTAY TGGACNMGNCCNMGNGARAARACNGAYYTNATHGTNTAYACNACNTGYCARCARMGNYTN GAYTCNYTNATGAARGARMGNYTNCARCARCARGCNATGMGNAARCCNMGNATGCARAAR CAYTGGGGNCARYTNMGNGGNGARYTNGAYATHATHCARAAYGCNMGNGARATHCCNGTN GAYTCNYTNMGNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNCCNACNTAYACNACNCCNYTNAARTCNTTY CAYAARGTNGGNYTNGARTCNAGYTCNACNGGNTCNTCNTTYCCNGCNGGNTCNGCNAAR CCNGTNGCNYTNGCNGTNMGNTCNYTNGGNMGNMGN------------AAYATGGAYAGY CCNTGGGGNAARTCNAAYCARGTNAAR------CCNTGYTCNYTNGCNGAYGTNATGAAY GARCARAARAGYGARGARYTNGCNTCNGARYTNCARAAYMGNGARAARGAYATHYTNAAY CARGARYTNGARGCNACNACNGAYGAYTCNGARGCNGTNGCNTCNTCNGCNAGYAARGAR YTNACNGAYGCNGARYTNGCNGCNAARYTNGCNGCNGARGARGGNAAYTGYGAYCCNAAY GAYGARATHATHGCNYTNATGYTNCARAARCARTTYGAYMGNGARTAYGAYGCNGCNYTN TCNCAYMGNGARCARAARTAYAAYGGNAAYTGYAARGTNGGNATHTCNTTYGAYAAYTTY AARMGNAARCAYCARACNGARTAYCARCAYTCNGARGAYGCNGARGAYGAYGAYGAYTTY TAYGARGARGARMGNCCNGARCAYCCNCARMGNACNCARTGGGARAAYGGNGCNACNACN ATHGGNAGYMGNGGNTAYGCNAARCARGGNGAYAGYATHGTNACNAARCAYGAYAARGTN ATHTGYGGNMGNMGNAAYGCNCARMGNYTNATGCARTTYCCNCCNGAYTTYGTNAGYGGN GAYGGNGARGGNATGGAYATGCARYTNCCNAAYMGNGTNTAYAAYGARYTNAARCARCAY TCNCAYTCNGARTCNAARAARGGNCAYAARGTNYTNGARAARAARGAYCAYTCNACNGCN ATHAARGCNGTNGAYGARAARACNMGNATHYTNATHTTYAARATGATHAAYTCNGARTTY YTNAGYTCNGTNGAYGGNGTNGTNAGYGARGGNAARGARGCNGTNGTNYTNAARGCNATH GGNGGNMGNAARGAYCAYGTNGARYTNCCNMGNGAYGTNATHYTNAARGTNTAYAARACN TCNATGAAYGARTTYAARACNMGNYTNAARTAYATHCARGGNGAYTAYMGNYTNTCNAAR GAYATHYTNAARAARTTYAAYCCNMGNAARYTNATGMGNATHTGGGCNGARAARGARTTY YTNAAYYTNMGNAARYTNCAYMGNCAYGGNGTNCCNTGYCCNGAYCCNYTNGCNCARAAR AARCARGTNYTNGCNATGACNTGYATHGGNGGNGARMGNCCNGCNCCNAARYTNAARGAY GTNGTNTTYAGYACNCARGAYTTYCARGAYGCNTTYGARCARACNGTNGARYTNATGAAR YTNATGTTYGAYAARTGYAAYATGGTNCAYTGYGAYTTYAGYCCNTAYAAYYTNYTNTGG CAYCARAARAARGTNTGGGTNATHGAYGTNGGNCARGCNGTNGAYMGNGAYAAYCCNAAY TCNAAYTCNTTYYTNTTYMGNGAYTGYMGNAAYATHTGYGAYTTYTTYAARYTNGGNGGN GTNCAYGGNGTNCCNACNGCNGARGGNYTNTTYAAYGARATHACNAARTAYGCNTTYGAR GGNGARGGNAAYGTNTTYGARTCNCARGTNCAYMGNTAYGAYGARGARGGNTAYGCNTTY GAYTTYTTYTTYGARYTNTCNAARTCNGCNCARTCNCARGARYTNTGYGGNGAYAGYAGY GGNAGYGARAGYGARGARGGNGAR---------------------GARMGNGTNTCNAGY MGNAAYGTNGCNYTNCARGAYGARYTNGAYAARMGNTAYMGNTCNCCNGCNGGNMGNAAY GAYAARGTNATHGAYCARGTNATGTCNYTNMGNACNAARGARTTYCARAARTCNCARGCN CARAARGCNAGYAAYATHCAYCAYYTNGCNCARGARMGNCARMGNATHYTNGAYGCNMGN AAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ACNGARGTNGAYGTN GGNATHACNGARTAYYTNGGNTCNCARACNGARTCNTTYTCNGCNGTNATHAARCARMGN TAYTCNGAYTTYATHGTNAAYGARATHGAYGARAAYGGNGCNATHGTNCAYYTNAARAAY GTNACNCAYGARGARGARGARGARGAYGGNGARAARGAYGAYCARAARTCNACNGAYGAY TCNAGYGTNYTNAGYGARTCNGAYMGNGARGCNATHCARAARATHGTNTCNGAYMGNAAY MGNGAYGCNACNCAYAGYATGYTNGCNCCNGAYGAYAARTCNATGMGNACNAARATHCAY YTNGCNGTNAARCARAGYTTYTCNCARYTNGARACNTCNACNACNGARGAYGARAARGGN CARAARGTNATHAARGTNACNTGGMGNAARGGNAARACNMGNGAYGTNATHMGNGAYGAR TGGCCNCARTCNAARAARTCNTGYMGNTAYGTNMGNTTYGTNYTNTAYAARGARAAYAAR GAYACNATGGAYGCNATHGGNYTNATHGCNAARAAYYTNMGNGTNMGNGARAGYATGTTY CARTAYGCNGGNAGYAARGAYAARMGNGCNAARACNACNCARGARATHACNGCNCAYMGN ATHCAYCCNAARAARYTNGTNAAYYTNAAYAARATGYTNTGGAAYATGGGNYTNGGNGAY TTYMGNTAYGTNGARCARCCNYTNCARYTNGGNCARYTNTCNGGNAAYMGNTTYATHATH GTNYTNMGNAAYATHCARGCNAAYGCNGARGTNGTNGAYACNTCNYTNACNTCNYTNAAR GCNACNGGNTTYATHAAYTAYTTYGGNATGCARMGNTTYGGNACNACNGCNATHCCNACN CAYMGNATHGGNAGYGCNYTNYTNAARGGNGAYTGGGARMGNGCNATHGAYYTNATHYTN GCNCCNMGNAAYGAYATHCCNGCNAARGAYAARTTYCARAARATHTGGGCNGARTCNMGN GAYCCNGCNGCNACNYTNGAYGTNACNCCNMGNTTYTGYGGNYTNGARMGNAAYATHYTN GARGCNYTNGTNAARMGNGCNAARCCNTTYAAYGCNYTNGARAARYTNCCNMGNAAYACN MGNYTNYTNTAYATHCAYAGYTAYCARTCNYTNATHTGGAAYAARATGGCNTCNAARMGN YTNTCNCARYTNGGNCAYGGNGTNGTNYTNGGNGAYYTNGTNYTNGAYMGNCARCCNTGG TCNCCNAARGGN------GGNGARTCNCCNTCNCCNGTNGTNGTNACNGARGAYAAYATH GGNAAYTAYAARGTNACNGAYGTNGTNYTNCCNYTNCCNGGNTAYGAYATHATHTAYCCN CAYAAYCARGTNGGNGARTGGTAYAARGARYTNYTNTCNTCNGAYGGNYTNGAYGTNAAY AAYATGAARMGNACNCARAARGAYTAYTCNYTNTCNGGNGCNTAYMGNCAYYTNGTNGTN ATHCCNAARGAYGTNTCNTGGACNCAYCAYCARTAYGAYGAYTAYACNCARCCNYTNACN YTNAGYGAYTTYGAYGTNATHCARGGNGARACNYTN---CARGAYTGYGGNGAYACNGGN ACNCARAARGCNGTNGTNYTNCAYATGTCNYTNCCNTCNTCNTGYTAYGCNACNATGGCN YTNMGNGARGCNATGAARATHGAYACNTCNTCNGTNTAYCARACNTCNYTNAAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATHTTYTCNCCNCCNAARGGNATHYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CARTCNCCNAGYGTNATHGGNGAYGCNGTNAAYAARGTNYTNAAY GARYTNGGNACNACNTTYGTNGARACNYTNYTNYTNGCNGTNAGYCCNGAYAGYGCNCAR GAYYTNGAYCCNGARGARGCNATGAGYYTNTCNGTNGTNGARGGNTAYTGGAARGCNATG GARGARYTNGTNGCNAAYGAYAARGTNYTNTCNYTNGGNATHTGYGAYTTYGGNAARGAR GGNYTNGARACNYTNTAYAAYTGGGCNCARGTNAARCCNTCNGTNAAYCARGTNAAYYTN GARTCNTGYTGYGTNYTNCCNAARGAYYTNACNGARTAYGCNAARTCNATHAAYGTNCAR YTNYTNACNCAYAAYGAYMGNCCNGCNTTYATHACNAARGARYTNYTNCARGARAARATG YTNGGNGTNACNACNGARMGNGAYAGYGAYGCNTGGACNCCNGARTGGGTNATHMGNTAY TCNGGNATHYTNAARTGYMGNGGNATHATHAARAAYAARGGNTAYATHTTYCAYGCNACN MGNGAYAAYAARAARMGNATHYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AAYGGNAGYTCNGARMGNAARAARAARMGNMGNAGYMGN TGGAAYACNGAYAAYGAYGAYAARACNGTNATHCCNGGNATGCCNACNGTNATHCCNGCN AAYYTNTCNGARACNCARCARMGNCARTAYGTNGTNCARYTNCARATHGARGARATHACN MGNAARYTNMGNACNGGNGARYTNGGNATHCCNTCNAAYCCNGARCARMGNTCNCCNTCN CCNGARCCNATHTAYAAYAAYGARGGNAARMGNYTNAAYACNMGNGARTAYMGNACNMGN AARAARYTNGARGARGARMGNCAYMGNYTNATHCARGARGCNATGAARYTNAAYACNGAY TTYAARCCNCCNAGYGAYTAYAARCCNCCNGTNGTNMGNGTNAAYGAYAARGTNATGATH CCNCARGARGARCAYCCNGARATHAAYTTYGTNGGNYTNYTNATHGGNCCNMGNGGNAAY ACNYTNAARACNYTNGARAARGAYACNGGNGCNAARATHATHATHMGNGGNAARGGNTCN GTNAARGAYGGNAARATHGGNMGNAARGAYGGNCARCCNYTNCCNGGNGARGAYGARCCN YTNCAYGCNTAYGTNACNGCNAAYAAYCCNGARAAYGTNAARAARGCNGTNGARCARATH AARGARATHATHAARCARGGNATHGARGTNCCNGARGGNCARAAYGAYYTNMGNMGNCAR CARYTNMGNGARYTNGCNYTNYTNAAYGGNACNYTNMGNGARAAYGAYGGNYTNCARAAR YTNMGNCARATHGCNGARAGYCARACNATHGTNACNAAYACNATHGTNTGYACNATHTGY GGNGGNACNGGNCAYATHGCNCARGAYTGYAARCARAARMGNCCNGGNGAYTCNTTYMGN ATGCARCARATGCARAAYCCNGCNGAYMGNGCNAARATGGAYAGYGARTAYATGTCNYTN ATGGCNGARYTNGGNGARGGNCCNCCNCCNCCNAARTCNGAYAAYCAR------GGNCCN AAYAAYTTYGGNCARAAYCARCCNCCNTTYAGYMGNCCNYTNYTNTCNAAYCCNCCNCCN AAYCCNATGGCNATHAAYCCNCCNTGGCARATG---CCNGGNAAYMGNCCNCCNATGTCN AAYCCNGTNCCNCCNCCNCCNTCNAGYTCNGGNCCNCCNYTNYTNAAYMGNCCNCCNATG GGNATGCARTCNACNGCNCCNCARATHAAYCCNATGGGNMGNYTNCCNATGCCNYTNATG AAYAAYCARGTNCARTCNCCNGCNGGNATGCARCCNCCNCCNAAYATGYTNCCNCCNCCN CCNGGNCARCARCCNCCNCARCARATGGGNAAYATGCARCARYTNCCNCCN--------- ------------CAYCARCARCCNCARCARCARCARCARCAYCARCAYCARCAYCARCAY CARCAYCARCAYCARCARTCNYTNMGNCCNTGGCARCARCCNGCNAGYCARGCNCARTCN ATHATGAAYCARGGNGGNATHTCNTCNACNGCNAGYATGGGNATHCCNCCNCCNCCNCCN TCNATGATGAGYGCNCCNCCNCCNCCNCCNGTNAGYACNCARGGNCAR---GTNCARCAR GCNCCNCCNCCNTGGATGCARCARCARCARCARCARCCNGGNAAYATGGGNYTNCARCAR CARCARCCNCCNCCNCCN------------------------------------GCNCAR CARCARCARCARCAR------YTNGARGCNYTNCARATGGTNCARACNGTNGAYGARTCN GAYYTNAAYGTNAGYTCNAAYAAYGCNACNACNGCNATHYTNATGCCNCARACNTCNACN GCNCCNGARCCNCCNCCNGGNTGYCCNGCNTGGGCNGCNMGNYTNYTNAARTGYGARAAR ATHGGNGAYTCNTAYMGNGGNTAYGTNGARAAYGARGTNAAYYTNGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------MGNAARYTNAGYACNGCNTTYAAYAGYGTNGCNTTYYTNAARGGN GGNTTYYTNACNTTYCARGCNTCNCAYTCNAAYYTNGTNGARAAYAARTCNAGYMGNTGY TCNACNYTNACNTCNYTNTCNCARCCNTGYATGCCNGTNAGYAAYGTNGGNCCNACNMGN ATHYTNTCNTTYYTNTAYYTNGGNAGYCARCARGAYTCNATGGCNCAYGAYGTNGCNCAR GTNAAYGGNATHTCNTAYATHYTNAAYGTNAGYAARACNTGYCCNMGNCCNCCNTTYATH YTNGARGGNCAYTTYTAYMGNATHCCNGTNAAYGAYAAYTAYTGYGARAARYTNYTNCCN TAYTTYCCNGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARTGYGARYTNTGYCCNCARMGNGAYGGNGCNYTNAARMGNACNAAR TCNGGNGGNTGGTGYCAYGTNGTNTGYGCNYTNTAYATHCCNGARGCNTGYTTYGAYAAY GTNCARACNATGGARCCNATHGTNYTNACNTCNGTNCCNCAYGARMGNTTYAAYAARACN TGYTAYATHTGYGARGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNMGNMGNATHYTNTCNMGNATHCARTCN AAYGGNCCNTAYTCNTCNGCNGGNAARGGNTCNGGNAGYGGNGGNAGYCAYGGNCCNGAY GAYMGNGAYGGNAAYATHGTNCCNYTNGCNTCNATGGTNGTNYTNCCNAARCAYAGYCAR YTNCCNGAYATHCCNGGNGAYGGNAAYYTNTAYTTYGARTGYATGYTNTTYGTNTTYGGN ATHATHATGATGTGYYTNCARTAYATHAAYYTNTAYAARACNGTNTGGTGGYTNCCNCAR TCNCAYGCNCARTTYGCNYTNAAYTTYTAYYTNATHGAYTTYAAYYTNGCNGCNYTNATH TGYGTNATHYTNGTNATHMGNTTYYTNATHTGYTTYGTNCARGARGTNCAYAGYAAYMGN ATGYTNTAYTGGCCNYTNTTYTGYYTNAARACNTCNATGGTNGGNTTYTCNGTNATHGTN ATGGTNTAYACNGGNTAYAARGTNATHATGGARCAYGGNGTNGTNACNAGYYTNTTYYTN TGYTAYCCNGCNGTNATHTAYGTNGTNYTNTTYGGNYTNGCNATHAARCCNYTNTAYCAR MGNAAYCARGCNTGGCCNMGNCCNGCNTAYGGNATGGAYMGNCCNGCNGGNCCNATGMGN ATHAARATGAARGAYGAYTCNCCNYTNTGYCAYACNTGYACNYTNACNCCNGAYATHGTN MGNGARGARGTNGAYGTNYTNAARMGNGAYTTYAAYAGYMGNYTNAARCARATHYTNTTY AAYTCNYTNACNACNTCNTTYTAYGCNACNGGNGTNCCNGTNTGGTTYTCNCAR---AAY ACNYTNTAYTAYGAYTCNTGG--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TAYATGACNTCNCCNGGNCCNGCNGARTCNGAYAAYAAYACNTAY TCNCAYTAYMGNCAYMGNTTYTCNATGCCNTTYACNGARTGGCCNATGACNYTNGAYMGN ATGTGGTAYAGYYTNGAYATHGGNCCNGTNCAYYTNATHAGYTAYTCNACNGARGTNTTY AARGCNGAYGGNACNTAYGCNCCNTCNCARAAYAAYTGGYTNATHAARGAYYTNAARGTN GCNAAYGARAAYMGNGARMGNACNCCNTGGATHGTNGCNTTYGGNCAYTCNCCNATGTAY TGYTCNAAYAARGAYCCNAGYYTNCCNTGYAARAARGARAARTCNAARATGGCNCARAAR YTNGARGAYATHATGTTYCAYTAYGGNGTNGAYGTNATHATHTCNTCNTCNGGNYTNGGN AAYGARATHTCNTAYCCNYTNTAYAARGGNTTYAARGTNGGNGAYAGYTTYAGYAAYCCN ATGGCNCCNGTNCAYATHAAYYTNGCNTCNGCNAGYCCNTGGAARGCNGARTAYAAY--- ---TCNTCNCAYGARGAYTGGGTNCAYTAYTCNGAYGAYGARAGYACNCCNATGAAYTTY GGNMGNGTNCAYGTNGTNAAYGCNAGYYTNYTNMGNTAYGARATHGTNTCNTTYGARGGN TAYAGYGTNYTNGARTCNGTNGARATHACNCARCCNCAYCAYGGNYTNTTYTCNAARGAY GARYTNCCNGCNAAYGTNTCNGCNAARATHGAYAARGARATHGARATHTCNGGNGGNAAY CCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARGAYYTNYTNACNCARATHCARACNYTNCARGAR GARAAYMGNMGNYTNMGNGAYGAYYTNACNAARATGAARCARAARCAYGAYGAYAARAGY CARMGNATHACNCARYTNAARAGYGAYYTNGARMGNCARAARAARAARGARGCNGARGAR ACNGCNGTNATGGARAARGCNGTNYTNCARGTNGARGARAAYYTNGTNACNACNACNCAR MGNGCNGTNCARGCNGARACNGCNGTNTCNAARYTNAARCARGARGTNAARGGNYTNCAR AAYCARGTNMGNTGYYTNACNGCNGARAAYGARACNTAYMGNAGYGGNGAYGGNGGNYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GGNGARTTYCCNGTNCARGAYYTNAARACNAARGARGGNGGNYTN YTNCARGTNTGYATGGARGGNATHGGNYTNYTN------ATGGGNCARCAYCCNTCNMGN CARGAYATHYTNCAYAARGARGTNAGYGAYYTNAARATGMGNAAYTGGATGTGYGCNAAY GTNGCNATGMGNGAYACNTCNAARGCNYTNGCNGTNTGYYTNCAYMGNMGNATHTCNCAR ATHCAYAARAARATGTCNCARGCNGTNGGNMGNGGNMGNCARTGYACNMGNAAYTGYACN TGGAAYMGNACNGARTGGTGYTCNGTNTGYGARMGNTGGTCNMGNGARATHATHGCNATH TGYGARCCNGAYTAYMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ACNACNGAYATHGCNGTNGCNTCNGGNYTNTGY GAYYTNGGNTCNAARGARAARGTNGCNCAYATHGAYAARGGNYTNGTNACNAARGCNGTN GAYAARATHCAYAGYATGYTNGARAAYYTNGTNGAYAARATHAARYTNAARGARGGNGAR ATHCCNGTNATHATHGTNGGNGGNGGNAGYATHYTNGTNGAYACNAARMGNCCNTTYMGN GGNGCNTCNGARYTNATHATHCCNAARCAYTTYGGNGTNGCNAAYGCNATHGGNGCNGCN YTNAGYAARATHTCNGCNAGYGTNGAYACNATGGTNAAYYTNATGGAYYTNATHGAYGTN AGYYTNATGGAYGCNAARATHAARGARGCNAARGARAGYYTNGARTCNCCNTCNGAYMGN GAYATHAARMGNGCNATHGARAARGCNAARAAYCCNTTYCAYAARMGNGCNMGNGARCAR GCNATHGARGARGTNTGYGARCARGCNAARTCNGARGTNATHMGNCARGGNGCNAARGAR AAYGARATHGARGTNYTNGARAARTCNGAYTCNGTNYTNGCNTAYATHGARGGNMGNGTN ---AAYATHAARGTNAARGTNGTNGGNGARATGAARCARCARGAY---GTNGCNGAYACN GGNYTNAARGTNTGGGTNGARCCNGARGARGTNGARACNYTNYTNGARATGAARGAYATH CAYCAYGTNAARCARAGYATHACNTCNACNGGNGCNTCNYTN---TTYGGNGARTCNGAR AAYGARAAYGAYTCNACNCARTAYCCNAARGAYCCNGTNATHGAYGAYAARTCNGGNGAR TGGATHYTNTCNGAYTGGGAYATHGARTGYYTNGCNGTNGGNTCNGGNATHTAYGGNTGY GGNGGNGGNGGNAGYATHCAYATHGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYAARTGGTAYAAYYTNAARGCNGGNYTNTTYYTNACN TCNATHACNGGNTGYTCNGTNYTNGCNGGNTTYGGNYTNACNYTNGGNATGGCNAARAAR ACNGAYCARMGNCAYTTYGCNAARGGNYTNGTNGGNTCNAARGARYTNCCNGARAGYGGN GTNGCNYTNGCNACNMGNGCNYTNGCNMGNGCNTCNGTNTAYACNGTNGCNGGNTTYGGN YTNTTYTGYTTYGCNGTNTGGAARATGATGGGNGTNCAYAAYATGACNGARTTYMGNGAR AARGTNGGNAAYGCNYTNCCNMGNGTNAARMGNAARGARAGYACNGGNMGNAAYGARTTY GCNACNATHMGNGAYYTNTTYCARTAYATHATHGAYGARGAYGARAARGCNAARGCNYTN AARGCNGARAARGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TGGCARATGTAYAGYAARGAYMGNGARCARCARATHCARGCNYTN AAYGAYMGNYTNAARGAYYTNTCNGAYCCNCAYCARATGACNGCNATGATHGARGARGCN TCNAAY---------CARAARATGGTNCCNYTNACNATGCARYTNGGNCAYAARAAYGAR GARATHYTNGARYTNMGNAARCARATHATGGGNYTNTCNAAR---GARYTNGARGAYATG MGNAARGGNCARTTYGARYTNCCNGAYAAYAGYAAYGARGARATHYTNAARCARCARATH CARGTNTGYACNGARGAYTTYAAYACNGARMGNAARGAYMGNGARCARGCNGTNCARAAR GCNMGNGTNYTNCARGARGAYAAYACNAARYTNACNGCNGARATHACNAAYYTNMGNAAR CARATHGARCARYTNAARAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TGYTAYGGNTGYCARTAYGCNAARTGYGCNGAYACNTTY------------GAYACN GGN------GAYYTNGGNGARTGYGAYGAYGAYCARTAYTGYGTNAARTAYAARACNATH GTNTGGATHMGNAAYTCNGGNGARATHATGGGNAGYTCNAARGARTCNCAYGTNGTNACN MGNTCNTGYGARTCNAARAARGGNCARAARGARGGNTGYGTNGGNTGGMGNAAYAAYGGN GGNGTNACNATHAARTGYTGGTGYGGNTCNGAYGGNTGYAAYAARGGNCAYTCNYTNGTN CCNACN------------------------------------------------------ ------------------------------------------------------------ ---------------------------MGNTAYMGNMGNGARGCNGARGARAARGCNAAY GARATHCARGGNYTNATHTCNGCNAARGAYGAYTTYCARAARMGNTGYGARACNGARAAR MGNGARYTNAAYAAYMGNYTNAARTCNATHAAYCARCARCAYAGYATGYTNCARAGYCAR AAYACNGARATHGARGCNGAYTTYATGAARYTNAARCARGAYATGGARAAYYTNMGNACN GARCAYATGCARACNGARGCNCARCAYGCNCARGARTAYCARACNYTNAARCARTCNAAR GARAARGARATHACNGAYYTNACNGAYGARATGTCNAAYGCNAARMGNCARAAYGARGAY YTNCARAAYACNATHGCNGCNYTNCARGCNCARATHCARAAYCAYGARACNGCNAARAAR AAYYTNYTNGARCARAAYGCNCARYTNCARGCNCARTTYCARCARCARCARYTNGARYTN CARAARAARAAYGARGARAAYGCNCARAARGCN---------------------AARYTN YTNCARCARCAR------------------------------------------------ ------------------------------------------------------------ ---TAYTTYGCNYTNGTNGCNAARCCNACNYTNTCNTCNYTNAAYAAYYTNTCNACNACN AGYATGACNAGYACNGAYGTNGAYGTNAARCCNAGYCARAARYTNYTNGARCARYTNACN CAYAARAARTAYTCN---GGNCCNTCNTTYCCNGGNATGAGYAARACNAARGGNCCNCAY TCNATG------------------AGYCARGARACNTAYGCNTGGAARYTNAARAARYTN AARAARACNATHAARGAYCAYATHTTYYTNAAYGGNGCNATHTGYGAYGARGTNYTNMGN ACNGARGARAARYTNGCNMGNGTNAARGARGARMGNMGNTTYYTNYTNMGNAARYTNYTN CARTAYCARTCNYTNAAYGARTCN---ACNGGNATHACNAARGCNGAYACNCCNGCNGCN ATGGTNMGNAAYYTNAARGCNGCNGTNGCNCAYAGYGARAAYGCNGCNACNGCNACNCCN GCNAARGGNTCNAARGGNGTNAARMGNAAR---------------------YTNAAYGCN TCNTCNGCNGGNGGNGGNGGNGGNCARCCNACNYTNTCNTCNGGNACNTCNTCNGCNGCN TCNGARAARAARAARAARCARCCNCARTCNGCNAARGAYATHYTNGAYTCNYTNCARGGN MGNCCNAARAARAGYAARTCNGCNGGNAARAARACNATHCCNCCNYTNATGYTNGAYTCN YTNGGNMGNCCNATGATHCCNATGATGYTNGGNGAYATHACNYTNCAYAGYATGGGNGAR ATHGTNACNGAYMGNTCNAGYTTYCAYTGYCCNGARGCNATHTTYCCNGCNGGNTAYTGY ATHACNMGNGTNTAYATHAGYYTNCAYAARGCNGAYTCNAARTGYYTNTAYACNTGYAAR ATHTCNGARGGNGARAAYGARCCNYTNTTYGARATHGCNCCNGARGAYAGYTCNGAYATH GTNTTYMGNGCNAAYAAYCCNTCNGARTGYCAYAGYYTNYTNYTNMGNGCNGTNAAYAAR TCNMGNGGNGCNGAYGTNGTNCCNACNGAYACNCARGGNYTNGAYTTYTTYGGNYTNTCN CAYTCNGTNATHCARAAYYTNATHCARTCNATHCCNGGNGCNMGNAARTGYTCNMGNTAY AARTGGGTNAARTTYGARATHGAYAARACNGARTCNAAYGTNAAYTTYGCNATHGGNAAR AAYGAYCCNACNATHAAYTAYGARGCNTTYYTNAARMGNYTNGCNGCNYTNACNCARGCN MGNCCNGGN---YTNGCNTCNCARATHGARAARTCNACNAGYYTNMGNTCNYTNYTNACN AAR---------ATGAAYTTYAAYGTNGARYTNGTNYTNGCNTCNGGNGGNMGNYTNGGN MGNATHGTNCARGTNGCNCAYGGNMGNACNGTNGCNYTNGAYACNCCNATGTGYACNYTN TTYACNAARGGNGGNAGYGCNCCNTAYYTNAGYYTNAGYATGYTNGARAARGTNAARAAY GTNCCNGARATHGCNACNATGAGYATHAAYTCNTTYGTNGARCAYGTNGAYAGYYTNMGN GARAGYGGNMGNMGNYTNGCNGARTTYACNTCNATGAARAAYAARYTNGTNYTNTCNACN YTNCAYGAYGCNAGYYTNCCNYTNCAYTCNGGNAARAAYGAYAARTCNGGNGTNGCNGTN TGGGGNAARGGNGGNAARACNATGYTNGAYCCNGGNYTNTAYATGAARATHCARGARACN YTNCARCCNGAYTGGYTNYTNGCNCCNAGYGAYGGNGAYACNGAYAARGARAGYACNGAR AARMGNTCNAGYAARGCNGTNGAYMGNACNYTNGAYTTYYTNGAYGGNATHGTNTCNACN ATGGARAARTCNGARGTNYTNAARAGYTCNAGYYTNATHGGNGCNGTNGTNGGNGGNTTY AGYGARMGNCARMGNCARMGNAGYGCNACNGARACNGCNACNMGNCCNGTNCAYGCNTTY YTNYTNGARGGNTTYCARAARGGNAAYTCNGARGARAAYATHGTNAAYGAYGARTCNTTY CARAARYTNYTNACNAARACNYTNAGYCAYYTNCCNAARACNAARCCNMGNYTNATGGAR ACNCCNTGGTCNCCNYTNCARGTNACNCARGCNGTNAARYTNGGNATHGAYGTNTTYTCN AGYGCNTAYCCNCAYACNYTNGCNGARAARGGNYTNGCNATGGCNGARGAYTTYMGNYTN ------------CARCARAARACNGGNGARGTNGARAAYGARAARAARAAYACNACNATH CAYTCNTCNACNATGGAYYTNAARGARAARMGNTTYTTYGARGAYTTYACNCCNGTNYTN GARGGNTGYCARTGYTAYACNTGYGCNACNTTYACNMGNTCNTAYATHCAYCAYYTNYTN AAYACNTCNGARYTNYTNGCNCAYGTNYTNYTNACNATHCAYAAYTTYGARCAYTAYTTY YTNTTYTTYCAYACNYTNMGNGARGCNATGMGNACNAAYMGNYTNGARGARYTNGARACN ATGYTNTCNAARCARGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TAYCAYTAYYTNCCNACN ACNGGNGTNMGNGCNGAYTTYAARMGNYTNATGAAYGARTTYATHTCNGCNCARACNGTN MGNTAYGARCARTTYAGYCARATGTGGMGNAARMGNMGNTTYGGNTTYYTNTGYGCNGGN MGNCAYTCNGAYMGNGARACNMGNGARTTYYTNGARMGNGCNYTNYTNATHGCNATHGAR TTYTTYYTNCCNCCNTAYCARTTYCARGTNMGNGTNGGNGGNYTNTAYYTNYTNTAYGGN ATHTTYATGACNCARCCNATHGCNCCNAARGTNAARGTNMGNYTNACNGTNAGYCARTGG GARGAYACNATHCARTTYCARCARGARGCNAGYGARCARAAYCAYYTNGAYGTNGTNTAY GTNTTYAAYAARATGYTNGARGARCAYGCNTTYCARTTYTGYTAYACNCCNTGYGARYTN AAYGARMGNACNYTNAAYCCNGARMGNGARGAYAAYGARGTNAAYYTNGCNGAYGAYATG AARGTNGARCARMGNGARATHGAYCAYYTNTTYAAYTAYGARTCNATGGARCARYTNTCN TAYYTNYTNAARCAYTAYCAYCARATGAARGTNGGNATGGCNGGNMGNAARGCNACNAAR CCNGAYAARTCNYTNGAYGTNGTNCARGGNTCNATGGTNGARGAYYTNGTNGTNATGYTN CARTCNTTYAARGARAGYTGYTCNAAYATHTAYAARCAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGACNACNGTNTGYGGNTGGYTNAAYTTYTTYTGYYTNMGNGARGTNAAYAARAARAAR GCNGTNCARCAYMGNATHCAYCCNAAYMGNCARCAYTAYGAYGCNGTNGTNGTNTGGAAY GGN---AARGARAAYAARAARACNAARGGNAGYATHAGYTTYGAYGTNATHYTNAARCCN GCNGCNGCNGAYTCNCCNMGNCCNTCNYTNCCNGCNTCNCCNMGNAAYAAYATGCARAAR GARYTNTCNGARGARAARATHGCNATGAARYTNAARAARGCNGARCARMGNAARAGYYTN ATHGARCARGARMGNATGGARCARYTNGCNMGNGARMGNCARAARGCNATHGARGTNATH ACNAARGCNCARTCNGARAGYCARGARTTYTCNAARAARACNGARGARAARYTNAARMGN TCNATGCARACNMGNMGNGARAAYMGNGARACNCARATHMGNGCNYTNCARGARMGNYTN MGNGARCAYTCNGTNAARGTNCAYGAYGTNCARAARGCNGGNATGGARATGGTNAARGAY TTYGARACNAARGCNGARCARAARYTNACNCARAARATGGGNACNTAYGARGARAAYMGN AARAGYCARYTNTGYAAYATGYTNGCNAARYTNCARGARCAYGCNAGYCAYATHAAYGAR GTNTGYGTNGCNAGYGARAAYMGNAGYGCNAAYACNGAYGARYTNCARGARCARYTNGTN YTNAARATGGARAAYGCNYTNAARAAYMGNGARGARCARYTNMGNATGATHCARGAYMGN YTNGCNGARCAYGARAAYMGNATHAARGARGTNCARMGNAARAARGGNATGGTNTCNTCN GGNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGTAYAGYGCNMGNTAYAARGCNGAYGGNCCNGGNTCNTAYCAY CCNTAYATHGTNAARCARTGGGCNAGYAARGTNYTNACNTAYTCNTCNCARTAYAAYGAY GCNGGNTGGAGYGCNMGNCARATHYTNGGNGARCCNAARGTNTTYCCNAGYCAYGGNGAY GTNCCNGGNGCNTGGGCNTCNTCNGGNTGGGAYAAYCCNGARTTYATHGARATHGARTTY GAYAAYGTNGTNMGNYTNTCNGAYATHCAYATHTAYGARACNTAYAAYCCNGGNTCNATH GTNAARGTNAARGGNMGNGARTCNTCNGGNCCNTGGACNYTNYTNTGGCARACNGARCAY CCNGTNMGNATHAAYGGNAGYMGNATHTTYACNCCNTAYYTNACNGARGTNGTNATGAAR YTNAAYCARYTNMGNYTNGARYTNGAYYTNTCNATHGTNYTNAAYTGGTCNGARYTNGAY GCNGTNCARYTNGTNGGNGTNMGNGAYGGNGAYGTNATHCCNATHGAYGAYGCNCARTTY GTNAAYGAYATGTCNMGNYTNATHAAYAAYAARYTNCAYAGYGAYATHCARYTNAAYATH AAYGGNAARTAYGTNTAYGGNCAYAARGCNATHYTNGCNATHMGNTCNCCNTAYTTYGCN MGNATGTTYGARACNAAYAARAAYGCNACNACN---YTNAARATHTCNAAYYTNACNTTY GAYGAYATHMGNATHGTNYTNCAYTTYYTNTAYACNAAYMGNYTNCCNGTNGGNGTNTGY ATGAGYAGYYTNGTNACNATGTGYAARGCNTCNGCNATGYTNGARGTNCCNGARYTNAAR TCNGCNGCNATHTAYAAYYTNYTNGARTGGATHAARAGYGAYAAYGTNGTNGARGTNTTY YTNCARGCNAARGAYGAYTCNCARYTNGCNGAYGTNAARTGYATHTGYCARACNTTYATG GCNTCNAAYYTNAARGARATGTCNCAYGARTCNTCNTTYAARYTNYTNTCNCARAGYGAY ATGGTNYTNGTNGTNCARGARGCNACNCARTCNYTNTGYATGAAYGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GTNCCNACNTCNTGYATHAAYGCNGCNAAYYTNCCN TCNGTNGTNAAYAAYATHGGNGTNGGNACNACNGTNCCNTGYATHGAYTCNGARTGYAAR GTNCAYCAYGAYGAYAAYTGYGAYAGYGTNGAYGAYAGYTGYTCNGARMGNAGYTCNAGY ACNTCNTCNAAYCARAARGARGGNAARTAYTGYGAYTGYTGYTAYTGYGARTTYTTYGGN CAYAAYAAYCCNCARGGNGCNAARACNAGYCCNAAYTAYTTYGARATHAARGAYMGNYTN MGNGARAARYTNAARAARAARAAYGARACNAARCAYAARTCNTCNYTNGTNCARAGYACN CCNGTNAARAARGARAARCAYCARAARGCNGTNATGGARAARMGNGGNYTNGAYGARYTN YTNAGYTAYATHAAYGGNACNGAYGARAAYAGYMGNGCNAAYAARGCNGCNAARMGNGCN MGNCARAARCARMGNAARYTNGARGARAARGCNMGNCARGAYAAYTCNCARAARTAYGAY GARAAYCAYMGNCARCCNAAYATGGCNAARTCNTTYTCNAAYTTYYTNTAYAARTCNCCN ATGACNYTN------GARTCNAAYAAYTCNGCNCARCARCCNAARACNGAYTCNYTNGCN CCNATGGGNACNAARAARTCNAGYAAYAARGARCARCCNATHCCNCCNCARYTNAAYAAR CARTCNATHCCN---------------------------------------CCNCARCAR CARACNAARCARTCNYTNCCNCCNCARCARAARYTNCARACNGCNCCNCARCARACNCCN GTNCARCARTCNACNAARCARATHAARCARACNYTNCCNTGYCARAAYAARYTNACNGTN ACNCCNCARCARMGNTGYMGNCARACNGAYAARCARCARGTNATHCCNCARYTNAAYCAR ACNTAYCARGTNTCNAARCCNTCNAARAAYCARAARGCNACNGARACNCCNGTNAGYYTN YTNAAYCAYYTNAARTCNCCNGAYCARGCNYTNYTNGARGAYAARAARTTYATHAARTCN TAYTGYGCNCCNAAYGGNATHATGGCNGGNTCNTCNAAYYTNTCNAARGGNTCNGCNGTN AARACNGARACNTCN------GTNCCNAARACNGAYTCNTCNTCNGTNGCNTCNGTNTCN AAYACNGCNACNGTNAGYAARGARACNGTNGTNAGYAAYGGNCARAAYTCNMGNAGYGGN AARTCNCCNTCNGARTCNCCNTCNTCNMGNGCNAARGCNCCNGTNGARCARACNAARGCN GCNAARAGYAARAARAAYAARAARAARTAYGARAAYGGNGAYATHCAYGAYCCNGAYGAR GTNTTYATGCCNMGNTCNGARTCNGARYTNGAYGGNACNGCNGAYGAYTTYGARMGNGAR YTNGARGARTTYAARMGNTTYTGYTTYGARACNTCNGARCCNAARGARAARMGNAARYTN GCNGTNAAYGTNAAYYTNAARGAYATHTTYAARAARAARACN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNTTYCAYTCNATHTCNGGNMGNGAYTGYYTN GARACNTCNMGNAARGARYTNGCNGCNCARMGNAAYGCNYTNACNCARGCNAAYAGYMGN YTNAARACNAARTCNGARAARGTNTTYGCNTTYAARACNGAYGGNGTNAARCCNGGNTCN AGYCAYGGNAGYATGCAYTCNAAYMGNCCNGTNTGGYTNTCNGARAARGAYATHGARCAY TCNAARGAYATHAAYATHYTNGGNYTNGCNCARCAYGGNAGYTAYAAYMGNGAYAARTAY GGNAARAARCCNMGNGTNCAYAAYTAYAGYYTNATHGGNGAYATHYTNGCNCCNAARATG GAYTTYAAYTCNCCNMGNAGYGCNGGNGARGARGGNAARACNGGNCCNGARGGNTAYAAR GCNAAYGTNATHTAYGGNCCNGGNMGNCAYYTNCCNTAYGAYYTNATGGAYAARTCNCAR AAYTCNAARAAYAARAAYCARCCNCARAGYGTNATHGAYYTNCCNCCNAAYATHMGNCAY CARTTYGGNAGYMGNGTNTGYGAYMGNYTNYTNTCNGAYCARGCNATHGTNACNYTNGCN YTNGARMGNCARMGNATGAARATGGGNCCNCCNMGNCCNTCNAARAARCARAAYGTNGAR GGNYTNCCNGTNGAYYTNCARAAYACNTAYGARAGYYTNGGNCAYACNACNMGNTGYAAY GTNTGYCCNGGNGTNAGYTCNGGNCAYAARATHAGYMGNACNAARGAYGARTTYAAYGAY GARGTNCAYCARMGNMGNGTNCCNAAYCCNGAYGARTAYMGNTAYCARMGNGAYGARYTN AGYATH---TGGGTNGARCARGAYGTNYTNMGNAARMGNATGGARCAYAARTGGAAR--- ------TCNGCNCCNCCNCCNACNGCNAARGCNCCN------GTNAARCCNAARCCNAAR CCN------AARCCNAARCARAARCCNAAYGAYGTNCCNCCNGAYCCNGAYGAYGAYATG AAYATHGTNTTYGTNACNCCNCCNYTNACNCCNYTNCCNCCNGARAAYGAYATHATHGAR YTNCCNAARAARTTYGARAARGAYGAYGARTTYTGGAGYTTYTAYGAYCAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYATHTGYAGYTCNTGYGAYTTYGTNGTN GAYTGYCARTAYMGNGGNACNAARCCNCCNTTYGCNGARCAYTTYGTNYTNCAYGARGAY TGYTTYGTNATGAARGAYCCNTTYTCNACNACNGGNGGNTTYATHAAYGTNGGNGCNATH TGYTCNCARTGYAAYCARAAYGTNTGYATGTCNAAYACNTGYAGYYTNTAYTAYACNMGN MGNTTYTGYATHMGNTGYGCNTCNGAYAAYATHATHGARTTYCCNCARGARYTNCAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TTYAARGAYGTNATG ATHATHYTNACNTTYCARGTNGAYGAYGGNACNGTNTTYAGYTCNGTN---------AAR GARGTNGARGGNYTNYTNACNGAYATHTGGAGYMGNGGNYTNCAYATGGAYAARYTNTCN GCNYTNATGAGYMGNATHGCNAAYAAYCCNGTNGTNYTNATGGCNGARGAYAARAGYATH GTNGAYAARYTNTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARGCNGARGAYGAYTCNGGNAARAAYATGTAYAAYMGNGARGAY GCNGTNATHCARGARGTNCAYTAYGGNAARTCNYTNCCNAAYAGYGCNGTNAAYACNGAY YTNGTNAAYCCNYTNTTYGAYTTYGARCCNCCNACNTAYATGGAYACNGARCCNGTNAAR TGGGGNCCNGARACNTTYAARCCNGTNTCNGCNGARCAYYTNAAYCCNCARGTNTCNTCN MGNMGNATHCARGAYMGNGARYTNCARGARATGAGYGAYGARGGNATGTGYYTNAGYATG CAYCARCCNTGGGCNTCNYTNYTNGTNTGYGGNATHAARATGCAYGARGGNMGNTCNTGG TAYACNCCNCAYMGNGGNMGNYTNTGGATHGCNGCNACNGCNAARGTNATHGAYAAYGAY GARATHAGYGAYYTNGARCARTTYTAYMGNCAYYTNTAYGCNGAYCCNAARYTNCARTTY CCNAARGCNTAYCCNGTNGGNTGYYTNYTNGGNTGYGTNAAYGTNGAYGAYTGYYTNGAY CARGGNCARTAYMGNGARAARTTYCCNGAYGGNGARTCNMGNTCNCCNTAYGTNTTYGTN TGYTCNAAYCCNTCNMGNYTNYTNGTNAARTTYCCNATGAARGGNMGNCAYAARATHTAY AARYTNGAYTCNCAYATHCAYCARGCNGCNAARAARGGNATHMGN--------------- ------------------------------TAYAGYAAYACNTTYACNGCNCCNCCNCCN TCNAARAAYTTYYTNCARATHTAYGTNAAYTCNTCNCARGTNATHYTNMGNGTNTGGAAR ATHYTNCCNCCNACNMGNGCNGAYGCNAAYCARGCNCCNTCNCARATHTCNTGYACNTAY GCNGARTTYCAYGARGAYGAYAARATHMGNGGNGARATHGARMGNAAYATGGGNCAYGTN GARYTNGCNTAYYTNGAYGARGTNGTNAAYAARCAYYTNGAYTGGYTNAAYMGNYTNCCN MGNAARGTNYTNYTNMGNATHGCNTTYTAYYTNGAYYTNGTNTCNATHGCNMGNYTNGGN CARGTNAAYAARCARTTYMGNGARYTNTGYAAYTGYGAYACNYTNTGGTCNAARATHTAY ATGGAYCAYACNAARAARCCNGCNACNCARGARYTNYTNATGYTNGTNGAYCARMGNGGN TGGAARGARGTNTTYTTYACNAAYAARYTNCARYTNCARATGCARATGMGNMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GGNAARAARGTNTAY MGNCAYTGYGGNYTNTTYGGNGAYCCNCAYYTNMGNACNTTYAGYGGNGAYTTYCARACN TGYMGNGTNAARGGNGCNTGGCCNYTNGTNAAYAAYGAYTAYYTNATHGTNCARGTNACN AAYGAYCCNGTNGARGGNAAYGCNGAYGCNACNGCNACNAGYAARYTNACNGTNATHGTN AARGGNAAYAARCCNTGYACNTCNAARAAYTTYCARACNTAYCARGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGGCNTCNCCNATHTAYCAYTGGTAYACNAARGARGTNTTYTAYTGGMGN AGYYTNGCNGCNACNYTNTGGTCNATHATHAGYYTNCCNATHYTNGTNTTYTGGATGTCN YTNTTYTTYAGYATHTCNYTNACNAGYCCNYTNACNTGGGTNTCNGAYGCNGTNGCNGCN GTNYTNTCNGTNCAYTTYGTNTTYACNYTNATGACNTTYACNYTNGCNGTNGTNTCNGTN ACNTGGTTYTCNATGCCNTAYATHACNGTNACNCCNGAYATHATHCCNTCNMGNYTNTCN TGYGTNATGGGNYTNTTYMGNTGGTCNMGNYTNCCNYTNATGGTNATHTGYGTNYTNATG GGNTCNYTNACNGCNTGGACN---------GGNATGGGNYTNTCNACNYTNACNGAYTTY GTNAGYACNGARGARTAYGARAARACNGTNYTNAAYGARMGNTGYYTNTTYGTNATHTGY TGYGGNATGTTYACNGGNYTNTGYTAYTAYTGYCARTTYTTYGCNMGNCARGARTTYTAY YTNAGYTTYCCNAGYATHCARMGNCARAARGTNTTYGARGTNMGNAGYGARACNMGNACN ATGGTNGARMGNAGYGCNTGGCARACNYTNCAYGTNATHAARTAYCAYTAYATHYTNTAY TTYYTNTTYGGNTCNGTNCCNMGNGGNTGGATHTGYCARTCNTTYGGNATHTGYGARGAY ACNGARTCNTTYCCNYTNGAYTCNATHGTNGGNYTNATGAGYYTNTCNYTNYTNTGGAAR GCNTAYYTNACNTCNTTYGCNYTNACNTTYGCNYTNTCNTTYACNYTNGCNYTNACNMGN ATHTTYCAYTCNGARCARYTNGARYTNCCNGTNACNAGYYTNYTNGARGAYTGGMGNGAR MGNACNYTNTCNGAYGCNYTNGTNTGYTCNTAYTCNCCNYTNYTNCARCAYYTNGCNTTY TAYGAYATGGCNTGYYTNAGYAARGTNGTNTCNCCNMGNYTNCARGARYTNYTNAGYYTN AGYCARCCNGGNGGNCAYCCNAARGTNTGGATGTCNGTNAGYCARTCNGCNGTNTCNGCN ATHCARGARYTNACNAAYCARGTNAARGARGARAAYTGGTCNATHYTNTCNAARGTNCCN ATHGCNMGNAAYGGNGGNGTNGCNAAYGGNGGNTCNTCNGGNGAYMGNTGGGAYGGNGGN YTNACNTAYMGNGGNGARGGNGGNGGNGGNGGNCCNGAYYTNGTNCARACNCCNGGNGTN GARACNGCNAARMGNAGYGTNATGACNCARYTNAGYCAYMGNYTNTGYTCNYTNCCNYTN YTNTCNCAYYTNGTNACNCCNAGYCARGAYACNAGYAGYMGNMGNYTNTTYACNTCNTGY CARAARCARATHTGGGCNGTNGARAGYYTNTCNCAYATHGCNGTNMGNGCNTAYACNGAR GAYMGNTAYGGNGTNGTNCARACNTTYYTNCCNGGNATHTTYACNGCNGTNYTNGAYYTN CAYGARGCNGTNGARAARCAYTTYAARYTNAGYACNTCNCCNMGNMGNCCNAAYAAYGGN TGYGTNCARGCNGCNGAYGGNGTNATHMGNTAYAARYTNCARTCNGTNYTNAARGCNTCN YTNTAYCAYATGACNAAYACNTAYAARTCNCAYYTNCARGAYATHAARYTNMGNCCNGAR GARATHAARAARYTNACNCCNTTYATHCAYTAYACNYTNTTYGARGGNATHCCNTAYACN TTYTAYGARCCNGGNACNACNTAYTTYTGGGTNCAYTTYGGNYTNGTNATHYTNGGNTTY GTNYTNGCNGTNGTNACNTGYATHGCNCARTGGAARAARCCNGCNCCNTAYGGNAARCAY GAYTCNTCNGARGARAAYTGGGGNCCNYTNATHCCNCARMGNYTNTCNCAYTTYATHTCN GAYGCNATHCCNGGNGTNYTNATGTTYTCNYTNGTNTTYTTYYTNTAYAGYMGNGARGAR AGYGAYAARAARGCNYTNAAYTAYGTNTTYTTYGGNYTNTTYYTNGTNCAYACNGTNCAY MGNGGNATHATHCAYCCNYTNATHATGAARTAYAARAGYGCNAARGTNTCNYTNGGNATH TGYATHGGNGGNGGNYTNCCNAAYGTNYTNTAYCARTGGYTNATHGCNAAYCAYATHGGN GTNGCNAARTAYGAYGAYTCNTAYCCNTAYGAYCCNMGNTTYATHGTNGGNGTNYTNYTN TAYGTNACNGGNTTYATHACNAAYMGNTGGGCNGAYTGGAARYTNMGNTCNYTNMGNAAR AARAARGAR------------------AGYAARGGNTAYTAYATHCCNTAYGGNGGNYTN TTYAAYTAYATHTCNTGYCCNAAYTAYTTYGGNGARYTNGTNCARTGGATHGGNTGGACN ATHGCNACNTGGTCNYTNTCNGGNTTYGTNTGGGCNTCNTTYGGNGCNGCNACNTTYYTN GCNMGNTCNMGNCAYAAYCAYAARTGGTAYCARGARMGNTTYGARGAYTAYCCNTCNAGY MGNAARGCNYTNATHCCNTTYGTNTTY--------------------------------- ------------------------------------------------------------ ------------------GARGARGARATGGCNGCNTTYYTNCCNACNYTNAAYYTNTCN ATGGTNGAYTTYGAYACNGTNACNGTNGCNGAYYTNMGNCAYAARTTYGARMGNAARAAR MGNMGNAARYTNTCNCCNCARGARMGNMGNAARTTYTCNGARCARTGYCARACNTTYATG TGGAARYTNACNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GGNAARCCNGTNAAYTAY CARGTNTCNGTNAARACNGGNGAYGTNMGNTAYGCNGGNACNGAYGCNAAYGTNTAYATH ATHATHCAYGGNAARAARGGNACNACNAARAARATGTTYATGGAYGAYTCNMGNGAYAAY TTYGARMGNGGNCARACNGARGTNTTYGARYTNAAYGCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGYAAYGAY TTYMGNCARGGNTTYTGYCCNYTNGGNYTNAARTGYAARAARYTNCAYTCNTTYGTNTGY CCNTGYTAYGCNGTNTTYGGNAAYTGYCCNMGNMGNGAYAARTGYTCNYTNYTNCAYMGN CAYAGYAAR---ATGCCNYTNTTYAARATHGARACNAAYYTNCCNAARGAYCARATHCCN GAYACNTTYYTNCAYGARGCNACNCARATHATHTCNTCNGARYTNGGNAARCCNGCNTCN TAYGTNTGYATHCARGTNTGYCCNGAYCARGTNATGAGYTTYGGNGGNACNACNGARCCN TGYGCNAAYATHACNYTNAAYTGYATHGGNATHGTNGGNCCNGAYAARAAYAARTCNYTN GCNCCNGTNYTNTCNAARTTYGTNGARAARCARYTNGGNATHAARCARGARMGNTTYTTY ATHTTYATHCAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GGNAGYGAYCCNCCNGAYTAYAAYACNGCNTCN---TTYCARGAR CCNCCNCCNACNTAYGAYTCNYTNTAYGGNMGNGTNAARGCNGCNAARGCNTCNTCNGAR GGNAAYGTNGAYTTYTTYAARACNTTYATHATHATHATHYTNTCNACNATHGGNTTYACN ATHATGYTNGCNGTNTTYATGGCNGTNCCNGTNTCNATGATHGTNATGGGNGCNATHTAY YTNGAYGAYTGYAARGCNGARMGNATGATHCCNATHTAYYTNATHGTNGCNGGNAGYTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GCNATHMGNGCNTTYMGNAARMGNATHTCNCARAAYGTNGGNNNN AAYTAYACNTCNGTNATGTAYTGYYTNACNTGYYTNGARTCNTGYGTNAARAAYTGYGGN MGNMGNTTYCAYYTNCARGTNGCNAAYAARGAYTTYYTNCAYGAYYTNATHAARATHATH GGNCCNAARAAYGAYCCNCCNCARATHATHCARGAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGNGGNATHCCNATHTTYATGGTNACNAGYGGNGGNTAYYTNMGNGAR ACNGCNMGNATHGTNGCNGAYTCNATHYTNAAYYTNMGNAGYYTNAGYYTNATHTCNTGY GAYGGNGCNGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TAYGARCCNGAYGCNGAYGTNACNATHGAR GCNATHMGNATHGCNGGNAARACNGGNGCNTCNTTYCARATGGGNAAYAAYCCNATGGAY GCNACNTAYMGNACNGAYGCNATHGTNACNGAYAGYTGGTAYMGN---YTNAARMGNGAY GCNGAYMGNGAYAARYTNYTNGGNGAYYTNCARGGNTTYAARGTNAAYMGNAARATGYTN AARGARGCNGGNGGNAAYTGGGTNTTYATGCAYTGYYTNCCNMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ACNGGNAARMGNYTNATGGGNAARTGYMGNATGYTNYTNCARGAR AAYGARGARYTNGGNAARATGATHTCNTCNGGNMGNACNGCNMGNYTNGARGGNGARATH TCNYTNCAYAARGCNYTNGTNGCNGARATGAARAARAAYCARAARGARYTNGAYGARTTY GTNGGNGARYTNGARGARGAYGTNGARGGNATGCARGGNATGATHTTYATGYTNCARCAR CARYTNAARGARGCNMGNGARCARATHACNMGNYTNCARCARGARAAYGARCARYTNMGN ACNYTNCARYTNCCNTCNGARCCNGARCCNGGNGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AARMGNGGNGTNGAYMGNAAYATHTAYCCNACNTAY TTYYTNCAYYTNGARCARGAYAAYGGNAARAARGTNTTYYTNYTNGCNGGNMGNAARMGN AARAARAGYGCNACNTCNAAYTAYYTNATHTCNACNGAYCCNACNGAYYTNACNMGNCAY GGNGARTCNTAYTGYGGNAARYTNMGNTCNAAYYTNYTNGGNACNCARTTYACNYTNTTY GAYCAYGGNGAYAAYCCNAARAARAGYGGNCCNCARGCNGCNMGNCARGARYTNGTNGCN ATGGCNTAYGARACNAAYGTNYTNGGNTTYAARGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TGGGARGTNGTNGCNAARAAYAARAAR---CARGGNGARTCNYTN AARATGTCNCCNMGNMGNMGNACNGARYTNATHGARAAYATGCCNMGNATHGARGTNAAR GAYCCNATHGARYTNGAYCARACNYTNTAYTCNGCNTTYYTNCCNAARGARCAR---CCN CARACNTCNACNGCNAARGARGAYGCNTCNAARCARAAYGGNAGYAARAARAAYCCNAAY AGYAARAGYAARAARAARGAYGAY------------AARAARCCNAARTCNGTNGAYATH GARTTYGCNYTNTCNCARYTNGAYCCNAARGARATGAARTCNGTNYTNGARAARACNCAR TCNYTNTTYCCNAAYCAYCARACNATHTGGYTNAARGAYATHGCNTCNTTYYTNAAYAAY AARYTNGARAAYGTNAARGAYATHGAYCCNGTNTAYAGYGGNMGNTCNTCNGGNTTYCCN YTNGAYGCNGTNCCNTCNGAYGTNGCNAARGAYYTNMGNAAYTTYATGAARCARTTYTCN AARGARACNYTNGAYAGYATHTTYYTNTAYGGNATHAARACNATGYTNCARGARTCNGCN MGNGGNGTNCCNGTNCAYGGNTTYAARYTNTTYYTNCARYTNATHTCNCAYACNAARTCN GAYACNGGNYTNGAYGAYATHCCNCARTAYYTNGARTTYYTNAARACNCAYCARAAYAGY CCNTCNAARTGYYTNTCNGTNYTNTGGGTNYTNGGNCARTGYGGNAAYAARCAYTTYCAY TTYGGNYTNAARGTNTGGYTNGARYTNATGATGCCNACNYTNGARATHMGNCARGTNGCN CAYTAYCCNGTNGARTAYYTNGARAAYYTN---------TTYAARAARTAYTCN---AAY YTNCCNAARAARAGYTAYGGNYTNGTNTCNACNATHGARTAYTTYCARGTNYTNGAYGTN TTYTTYACNCCNAARTTYACNYTNGCNAGYGAYYTNAARAARMGNYTNATHACNGTNTAY CCNACNATHAARACNYTNGCNTAYGGNGARGAYCCNTCNCARAAYYTNMGNAARTTYTTY CCNTCNTAYYTNTCNMGNTTYGCNAAYGTNMGNTCNAARGARATGAARGARGARYTNYTN GCNTCNATGACNGARTGYYTNATHACNGAYAARCARTCNTTYGGNGTNTGGTGYCARYTN TAYACNAARTAYYTNCCNACNTCNAGYCAYYTNYTNGAYCAYATHAAYAGYAAYTGGTCN AARYTNTCNTCNMGNTTYGAYAARAARATHYTNMGNGCNACNYTNMGNTCNTTYTCNGTN ACNAAYGARGARYTNGARGTNCARACNAARGGNAARCARAAYGGNYTNAARYTNTCNCAR ACNGCNTCNAARGAYYTNATGATGAARYTNAGYGCNGCNCAYTTYCCNTGGAGYYTNYTN GTNTTYTTYATHACNTCNATHTTYGCNGCNATHGTNGTNTAYGAYATHACNTCNAGYCCN ACNTTYMGNTCNTCNAARACNATGCARTTYYTNGARMGNTAYGGNTTYYTNGCNYTNYTN GARAARACNTAYCAYGGNGTNCAYAAYATHTCNACNGTNTCNGTNAAYTGGYTNAARGTN AAYTTYCCNATHTTYTAYAAYCARGTNYTNGARACNGTNGTNCCNYTNTCNATHACNGTN TGGAAYAGYTCNMGNGAYTTYATHATHAAYGCNGARGTNCAYTCNMGNCCNTAYMGNGTN YTNGCNATGGARAARATGATHCARTTYTAYCAYTGGGTNTAYGAYYTNTCNCCNGARTTY TGGYTNMGNTGYGARGARYTNACNTGGYTNTCNTGGGAYYTNYTNAARGAYTAYACNTTY MGNATHTGGGTNCAYACNCARTAYTTYGCNGGNGARGCNCAYCAYTGGYTNACNGARCAY GTNYTNACNGGNTCNYTNTCNAARGARTCNATHAARGAYACNGCNYTNTGGGGNGTNGGN CAYYTNCARAAYTGYACNACNYTNYTNGTNTCNTGG------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYMGNATGGCNGTNGAYGGNATHACNATHYTN GAYMGNCCNGCNATHGTNTAYGGNGGNATHAAYGCNAARACNGTNCAYGCNCAYGARACN GARGARTAYYTNAARGGNAARAARYTNGAYAARGARGTNATHAARGTNGCNYTNGARATH YTNAARGGNGARYTNAAYCCNGAYGARGAYCARYTNYTNGCNTCNCCNAARTAYMGNAGY GAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GTN GTNTCNTGYTGGAAYTTYYTNTTYTCNACNYTNGGNCAYGGNCAYYTNTAYCCNYTNAGY CARGARGAYGCNATGYTNYTNYTNGGNTTYGAYMGNCCNTTYGAYAGYATHAARTTYGGN CCNACNACNGGNAAYYTNACNYTNATGMGNTGGTTYMGNCARYTNAAYAAYCAYTTYAAR GTNAGYGGNMGNTGYTAYTTYATGTAYAARCCNMGNGGNMGNAAYMGNACNAGYGGNATH ACNTCNGARATGGCNYTNGARAARYTNAARACNGGNYTNMGNGAYAARCAYTCNACNTTY ATHTAYCAYTGYCAYAAYCAYTAYTTYTGYCCNGTNGGNTTYGARGAYTCNCCNYTNTAY CCNYTNGAYGCNTAYAGYGAYAARATGTCNGAYGAYTCNATHGARAARACNTGGATHYTN ATHGGNGAYACNAGYMGNAARTAYGGNCCNTTYCAYTGYAARAGYTGGGAYGARATHTGY YTNGAYYTNAAYTGYGARAAYCCNGARTAYTAYAAYATHMGNCARTCNTGGAAYGGNYTN ATGAARMGNCARAARAAYAARMGNATHGGNGGNAAYYTNCAYTGYATHATGTGYTTYCAR TCNCCNCARMGNACNCAYAAYAAYCARAAYCARCAYAAYACNTCNAGYATH--------- ---------------------------------------------TCNYTNTCNCARCAY YTNMGNGARGCNGARGAYMGNYTNAARGARTTYGGNACNGTNATHTCNAGYATHACNAGY AAYGGNCCNCARGAYGARATHTTYGAYCARATGAARCARATHGAYAAYGARATHGARATG AARYTNAARATGYTNGARAAYGTNACNTCNAAYAAYCARAARGCNGTNCARGARYTNGAR GCNGARAARGARGCNYTNTCNTTYAARATHGGNATGCAYAARAARAGYATHAAYYTNTCN GARGAYGARYTNMGNCAYYTNATGAARGARAARTCNYTNYTNGARAAYGTNCCNGTNGAY GARAARGTN---CAR---AARGTNAARCARYTNGARGCNGARGAYYTNATGTTYMGNAAR CAYYTNGGNATGGARATHMGNAARGTNAARGGNGGNTGYYTNCARGTNGCNTTYAAYCAR ATHGAYCARAARCARCCNAAYTCNYTNTTYYTNTTYTCNYTNACNTTYGAYGARAAYMGN CARTAYGTNATHTCNGAYTGYAARCCNCCNATHTCNGAYYTNGARGAYATHGTNCAYAAR YTNAAYGGNGAYAAYGAYTTYMGNAARTTYGTNCAYACNATGMGNAARMGNTTY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNAARMGNMGNTAYAGYGAYGTNYTNGAR---GAYYTNTAYMGNGGNCCNCARGAR TTYATGGARGCNGGNGTNMGNGGNTTYYTNGTNACNTCNYTNCCNGAYMGNGARGARCAY TCNATHGAYGARACNGTNAARGTNYTNMGNAARACNTGYGTNAARYTNTAYGGNGGNATH AARCCNYTNAARMGNGARGAYGCNTCNTTYGCNAARGGNTAYGTNATGATHGAYTTYATG GAYCCNGARACNGTNGTNGCNYTNCCNCAYCCNGAYGCNCARAARAAYGCNGARGTNGAR AARGCNAARGCNGCNGARGARGTNGCNAARGTNGARGGNGARGARATGGARCARGARAAR CARGARCARGARGARGARGCNAARCCNGARGAYGGNGAYGCNGGNGGNGGNGAYGCNGGN GGNGAYAARGCNAARGCNGARGGN------------------------------------ ---------------------------------------------GARGCNGARAAYACN ACNGARGARGTNAARGARAGYAARCCNAARGARGARAARGARAARGARGARAARAAR--- ------------------------------------AARAARGARGAYACNMGNMGNMGN MGNGAYGAYGARAARAARCCNYTNATGYTNGCNCCNCAYAARTTYAARGGNTTYMGNACN GARYTNMGNAAYATHATGTTYATHAARTCNGAYATHCCNGAYCCNGTNGARGCNGTNACN GCNTGYTTYGAYYTNATGYTNAAYMGNAARCCNYTNTAYACNGAYTGYGTNAAYCARYTN YTNCCNGTNCARGGNGTNTGYGAYAAYGAYTAYAARCARYTNGARATHATGTGYMGNMGN GTNYTNGTNCCNTAYATHGGNGARMGNYTNGARGARCCNCCNAGYTTYGGNGTNATGYTN GTNAAYAARATGTGYGARCCNGGNGCNGARGTNYTNYTNGARGTNGTNMGNAGYGCNATH TGGTGYYTNAAYCCNTGYGCNTGGCARTGYTCNCCNTGGGCNGARCCNGAYGTNGTNATH CAYATHGARATHATHGGNAGYAARATHATHYTNAGYGCNATGCCNCAYTAYATGAARTAY MGNCARTAYAGYCCNTTYGCNYTNTAYGARYTNGGNCCNGGNAARCCNGARGAYGARGAR ------AARYTNYTNAARGARMGNTCNGAYGAYTTYMGNCCNMGNGGNTGYMGNGGNMGN MGNAARGAYAARAGYGGNMGNCAYAARGARCARGAYAARGGNGARAARAARGARGGNGGN GARAARGARAARGCNAAYAARGAYTCNGCNGARACNGGNGARAARGAYACNGARCARTCN GARCARACNGARCARACNGAYCARACNGARGARGTNAAR--------------------- ------------------------------------------------------------ ---------------------------------------------GARMGNYTNAARMGN ATHAARMGNAARACNGARGARAAYATHYTNGTNYTNYTNTCNMGNATHTCNGTNAARACN GAYCCNTCNCARTAYYTNCCNAARTAYGCNGTNYTNTCNACNYTNACNAARTAYATHGGN GTNGTNCCNAAYCCNATHCARMGNTGYATHMGNACNYTNTTYMGNGTNTTYCAYAAYCCN CAYTGYTTYGARTCNGTNYTNYTNGARCARGCNCCNGCNYTNATHGTNAARAAYYTNATH ATGGAYCARGAYGGNAARTTYCCNTCNGTNYTNTTYAAYCARGARGGNGGNCARAAYGGN CCNCARACNAGYMGN---AARATHAAYTTYGAYGAYYTNTTYTCNTGYTCNCARAGYTCN GARACNCCNTCNGAYTTYGARATGCARATHCARTTYGARTTYGGNGGNGAYGCNTAYAGY AAYATGATHCAYCARMGNAGYTTYMGNTCNYTNTTYMGNGGNAARTCNTCNAGYMGNGGN ATGTCN---------MGNGAYACNTCNTAYATGCAYTCNTCNATGACNCCNGARGAYYTN ACNMGNGTNMGNATHMGNAGY---GGNATHAAYYTNATGAARGCNATHACNTCNYTNGCN YTNTCNMGNTAYGGNGAYGGNGARATHCARMGNATHTGGTCNMGNGGNACNGARTCNGAR AARYTNATGTGYGCNATHAGYYTNYTNCAYATGCCNATHGGNTGYGGNCCNYTNCAYMGN MGNCARATHATHYTNAARCAYGAYGCNYTNCAYCARGTNATHCCNYTNYTNTTYTGYAAR GARGGNCCNYTNGTNMGNGARGGNATHGTNACNGCNYTNAGYYTNYTNGCNCAYYTNTTY MGNATHCARAARGTNCCNAARATHMGNAARYTNATHAAYACNTGYCCNGARTCNAAYCCN TTYAARMGNGGNAGYCCNGAYTTYCARATGTCNAAYAARATGAAYAAYGGNAAYGAYGAY ATHTGYMGNTTYGARCAYATHTCNGAYAARYTNGAYAAYTTYATHGTNGTNGAYAAYGGN GARMGNAARGTNTTYMGNGCNTGYAARGARATHYTNATGAARAARTCNGARGTNTTYTGY GCNATGYTNGGNGGNGGNTAYGCNGARGCNGAYAARGTNGAYATHGARTTYTCNGAYGTN AAYYTNTCNGGNTTYGARTAYGTNYTNCAYTTYYTNCAYGGNTGYGAYTCNGGNTGYGCN GTNATHGAYYTNYTNTCNTTYATHGAYTTYATHYTNGAYMGNTGYATHGAYATHGTNACN GTNGCNGAYMGNTTYYTNGTNCAYGAYYTNATHCARTAYYTNACNTCNGTNYTNTCNCAY ACNTGYYTNTAYACNMGNACNGTNACNGAYATHATHTAYYTNGCNTCNACNTAYAARYTN AAYTGYYTNGCNACNGAYTGYGTNGTNGAR------------------------------ ------------------------------------------------------------ ------------------------ATGCARAARYTNAARAARGGNATHTCNCAYGCNCAY AGYGTNMGNYTNMGNCARYTNAGYCAYATHYTNTAYGAYAARGTNACNGARATHATHAAY ACNGGNGARYTNTCNCARGARATHYTNGAYAARCAYGTNTCNATHACNGCNGTNAARATG ACNAARGAYATGAAYAAYGTNAARGTNTAYTGGGARGCNGAYMGNGAYGAYTGGCARGAR YTNGARCAYYTNYTNTCNTCNCAYAGYGGNAARYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNATGGARGGNYTNATHYTNAARTTYACNAAYGTN GTNAARGGNTAYCARTAYMGNTGGYTNGTNYTNGAYCCNGARTCNGGNATGYTNGARTAY TTYGARAARGARGARCAYAARAARCARMGNCCNMGNGGNTCNGTNCAYYTNGCNGCNGCN GTNGTNTCNCCNTCNGARGARGAYTCNCARACNTTYATHGTNAAYGCNGCNAAYGGNGAR ATHTAYAARYTNMGNGCNTCNGAYGCNMGNGAYMGNCARYTNTGGGTNGAYMGNATHMGN TCNACNGCNGARCAYCAYACNGCNCAYTTYGCNCARTTYCCNCARCAYTCNCCNAARYTN GTNMGNAAYGAYTCNTTYACNTCNCARCCNAGYMGNMGNCARGAYTCNGGNMGNMGNACN MGNGGNTCNATGGARAGYYTNCCNACNAGYAARMGNTCNCCNMGNGAYGARGCNTTYCAR GARGTNMGNGARTTYCAYYTNGAYGCNGARGAYTGYYTNMGNAAYYTNGARGAYAARATH TCNGCNYTNTCNCCNTCNGGNGARCAYATHAAYTCNYTNGAYTCNGARYTNYTNYTNYTN AARGCNACNTCNGCNGCNACNYTNMGNTGYGTNCARGAYTGYATHTCNYTNYTNCARAAY GCNGARCCNTCNTCNNNNAGYCCNMGNAGYCCNATHGTNAAYGAYCARCCNMGNYTNAGY GTNACNGARACNGAYGGNAAYATGGAYTAYCARGCNAAYYTNCCNAARGARGARGARGAR GTNYTNGAYGARGARGTNTAYGARGAYAARGAYYTNGARGGNGTNGARGARCAYAARTCN ATHATHYTNCAYYTNYTNTCNCARYTNAARYTNGGNATGGAYYTNACNAARGTNGTNYTN CCNACNTTYATHYTNGARMGNMGNTCNYTNYTNGARATGTTYGCNGAYTGYATGGCNCAY CCNGARGCNTTYYTNAARATHCCNGAYATHCARGAYCCNGARGGNMGNATGYTNGCNGTN YTNGARTGGTAYYTNACNTCNTTYCAYAAYGGNMGNAARGGNACNATHGCNAARAARCCN TAYAAYCCNATHATHGGNGARACNTTYCAYTGYTCNTGGYTNAGYTAYGTNGCNGARCAR GTNTCNCAYCAYCCNCCNATHTCNGCNTTYTAYTTYGAYTGYCCNAGYAARMGNGTNAAR ATHAAYGCNTCNATHTAYACNAARTCNAARTTYATGGGNATGTCNATHGGNGTNTCNATG GTNGGNAARGTNMGNYTNMGNYTNGARGARTTYGAYGARGAYTAYGTNTTYAGYYTNCCN AGYGCNTAYGCNMGNTCNATHYTNACNGTNCCNMGNGTNGARYTNGGNGAYAARGCNTCN YTNACNTGYGAYAARACNGGNTAYCARGCNAAYATHATHTTYCAYACNAARCCNTTYTAY GGNGGNAARYTNCAYCAYATHACNGCNGAYGCNAARAGYACNMGNACNGGNGARAGYATH TGYAARGTNCARGGNCARTGGAAYGGNGTNATGGAYTTYACNTAYACNAGYGGNGAYACN CARTCNGTNGAYGTNTCNGARYTNCAYGTNACNMGNAARTCNGTNMGNCCNATHGAYMGN CARGARGARCAYGARTCNMGNMGNYTNTGGCARCAYGTNTCNAAYGCNYTNMGNYTNAAY GAYATHAAYACNGCNACNGARCAYAARAARGGNYTNGARGARGTNCARMGNGARGGNGAR MGNCAYMGNAARGCNATGGAYYTNCCNTAYGTNGGNAARTTYTTYGAYAAYGTNGAYGGN ACNTGGGTNCAYAARAGYYTNCCNAARACNTTYATGCARGARMGNAAR------------ ---------------------------------------------------------ATH CARAARCAYCAYAARACNTTYYTNTAYTGYGARATHGCNTTYTAYATHYTNGGNTTYYTN ACNTTYTGYCAYGCNGTNTCNAGYGGNGGNMGNTAYAARTGGYTNTGGTTYGCNACNATH GCNCAYGGNYTNACNGTNGARTAYGTNAGYTAYGTNATHCCNGAYATHGAYAAYTTYTGG CAYGGNCARTCNATGGTNATGYTNATHGGNCARMGNYTNCCNYTNCAYATHYTNYTNGTN TAYCCNGTNTTYATHTAYACNGCNGCNGTNGCNGTNTCNCAYATGAAYYTNAARTGGTGG GCNGARCCNTTYGCNGTNGGNYTNTCNGCNGTNYTNYTNGAYATHCCNTTYGAYATHATG GGNATHAARYTNYTNTGGTGGTCNTGGCAYGAYGAYGAYCCNAAYATHTAYGAYMGNCAY TAYTGGGTNCCNTGGACNTCNTAYTAYTTYCAYGCNGCNTTYGCNTCNTCNTTYGCNTTY ATHTTYTTYGGNGCNAARAARYTNTTYTGYTCNMGNGCNYTNAARTTYCARAGYAGYAGY ATHTTYYTNGARTTYCCNGTNYTNYTNATGACNGGNYTNTTYTCNATGCCNYTNGGNGTN YTNCARTTYATHCCNGTNTAYCAYTCNYTNCAYGAYACNYTNGGNATHCAYTCNGARGTN TGYGTNYTNYTNTTYYTNGGNTTYTTYGCNYTNGTNGTNTGGTGYTCNGAYMGNMGNCCN TTYGARTTYGCNMGNCAYAARGGNGGNAGYGTNYTNAGYYTNCCNATGYTNGTNGTNGTN YTNCAYTAYGCNYTNTAYGTNTTYYTNGTNATGACNGCNAAYCCNAGYAARATHMGNTCN ACNGGNYTNCAYCARCCNGTNGGNCCNTGYAAYAARCARGTNAARGTNCARACNCCNYTN GGNCAYGTNYTNCARAARTCNAAYTAYYTNTGYYTNAARAAYTAYTCNGARGAYTAYTTY ACNYTNGAYTGYYTNAARAARCCNCCNGTNGGNAARACNGARTGGTAYACNATHTGYGGN ACNCCNTAYCCNAAYCAYACNGARTAYATGATHGTNATHTGYGCNTTYTGYGCNYTNGGN YTNTTYTGGTTYTTYCARGCNYTNTGYCARTCNGGNCCNCARCCNYTNGTNGAYTCNGTN MGNMGNAAYTTYTTYACNGTNTTYGCNAAYATHGCNGTNTTYGGNATGTTYTCNATHYTN TTYGTNATHGGNTCNGAYACNTCNTCNAGYTCNGGNAAYGAYGTNCCNAARTTYMGNTAY ATGACNTTYTTYTGYYTNGGNGTNGGNATHYTNTTYAAYYTNATHTTYTAYACNTCNGTN GARAARAGYMGNTCNTCNAARTCNAARATGTCNTGGAARGAYTGGYTNAARGARCAYCAR TTYTAYCARATHGGNTTYYTNTAYATGTTYACNMGNYTNTAYTTYAAYATHAGYCARGTN TAYTTYGGNATHTAYYTNACNAARACNATHCARYTNAARAARATGTAYGTNGCNGTNATG CCNYTNTTYGTNTAYGGNTCNGGNTTYYTNGCNTCNATHYTNGCNCCNACNYTNAAYAAR YTNTCNGGNMGNAARACNTCNTAYTTYGTNGGNYTNGTNTTYGGNYTNAGYGCNACNATH TGGYTNTAYTTYATGGAYACNGGNAGYAAYCARATGTAYGGNGCNTCNACNTTYYTNGGN ATHGCNAAYTCNGTNYTNYTNATHACNTCNYTNTCNATGACNTCNGAYYTNATHGGNAAR AAYGTNGARAGYGGNGCNTTYGTNTTYGGNGCNATGAGYTTYACNGAYAARYTNTCNAAY GGNATHACNATHYTNYTNATHGARAARTTYGAYCCNTGYCAYGARAAYTGYCCNTCNCAR TCNGAYTAYTAYMGNCAYATHGARTCNATGGTNCCNGGNGGNGCNAAYYTNGCNGCNTTY ATHGTNYTNYTNACNYTNATHCCNCARACNATHGGNGTNMGNMGNAARAARCCNAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARGARGARGAYYTNCCNCCNGGNGTNMGNAARCAYAAYMGNTGYCAYAGYAGY AGYTCNGARGAYGARACNGAYAARAARAARAARTCNATHGAYATHGAYTCNTCNGAYTCN GARTCNGARAARTCNGAYCAYAARAARGARGARAARAAYAARGAYAGYTCNCARGGNGAR GCNGTNGARTCNAARTCNGTNAGYAARGARAARGARATHCCNTCNAARGCNGAYMGNGAY TCNMGNTCNAARTCNMGNTCNCARTCNCCNTCN---CCNAARMGNMGNMGNTCNTCNGAY AARAGYMGNMGNTCNMGNTCNMGNTCNMGNGAYMGNMGNCAYMGNMGNGAYAARAARCAY MGNTCNCAYMGNTCNMGNTCNAARGARMGNMGNMGNTCNMGNGAYMGN------CAYMGN CAYAARAARGAYMGNMGNMGNAGYMGNAGYMGNAGYMGNGARMGNMGNGAYMGNMGNTAY AGYMGNMGNAGY---AGYMGNGAYMGNGAYMGNMGNMGN--------------------- ---------MGNAGYMGNAGYMGNGARMGN---MGNGAYAGYMGNAGYCCNAGYCCNCAY GAYGGNAAR------GTNATHAARTTYGGNAAYAARGTNATHAARCCNGGNGCNAGYTTY GGNMGNCCN------TCNTCNAAYTTYTCNAARCCNGTNACNTTYAARGARAARATGMGN CARCARYTNATHAARGCNATHGARGARGGNGCNGAYACNAAYGARGTNYTNGCNAAYAAR GGNGGNTCNACNATHTGYACNCARAGYGCNGGN---GTNCARCARCARGTNATGCCNAAR CCNAARGGNCCNCCNGTNCCNYTNATGGAYACNATHGTNCCNTCNACNGCNAGYYTNGCN GCNYTNACNGTNACNGCNTCNGARGCNGCNATGCARTCNATGYTNGCNYTNCARAARGAR GCNACNGARAARACNGGNATHGARATHCCNAARTAYTAYAAYCCNGCNGCNATHAAYCCN ATGAARTAYGCNGARCARGTNCARAARMGNAARYTNYTNTGGTCNAARGCNAARGAYAAR GAYGTNAAYTCNCARTGGCAYGCNACNAGYYTNTCNGGNGAYGCNGAYGAYAARTCNAAR GARAARTTYMGNAARYTNATGGGNATHAARAAYGAYAGYGGNAAYGCNGCNCCNAARGAR GGNGARAAR---------------GARGARMGNAAYAARCARYTNTTYGAYCARYTNAAY AARGARTAYGARTTYGCNMGNATGGCNACNCAYACNCAYMGNGGNATHGGNYTNGGNTTY AGYTCNTCNGGNTAYCCNCARACNTCNTCNATH------CCNATHCCNGARGAYAAYCAR GARAARCCNCCN---CCNMGNGAYGAYGARGARYTNAAYGCNTTYTCNAAYGGNAAYGTN GCNTCNATHACNTTYAGYTCNGAYTCNAGYGAYGARAAYGAY---GAYAAYTAYCCNGAY ACNACNGGNTAYATGYTNYTNCCNCARGARCCNGCNGGNTAY---GAYGAYGCNGAYGAY GAYACNGAYGAYGARATHATHGARAAYCARGCNGAYMGNCARTGYGARTCNGARACNAGY GAYACNMGNGGNTCNATHACNGARAAYAGYAAYCCNGAYMGNYTNCCNGAYGARGTNATH CARTCNGARGGNGTNGCNGTNGCNCCNMGNGTNACNGCNTCNTCNACNTCNCAYCAYCCN GCNTTYYTNGCNAARTTYCCNGAYGGNAARATHCCNTCNTAYATGCARGTNCCNGAYATH CCNACNAAYMGNGAYGAYGTNYTNTGGAAYAARAARMGNGAYGGNAARAGYTCN---TCN YTNGAYACNGCNGARGAYAARAARATHYTNMGNGCNATGTCNGGNTTYTCNYTNCCNTCN GARAAYGTNCCNGARTGGGCNAARAGYATGTCNGARGAYCARTGGAAYGAYGTNATHACN CARAARTTYMGN------------------------------------------------ ------------------------------------CAYYTNCCNGCNCAYGCNTTYYTN ATGGARGAYGGNATHACNGGNTCNYTNAAYATHGCNGCNTTYAAYGTNMGNCAYTTYGGN MGNGGNTTYATHACNGAYAARCARGARGCNTCNAAYYTNATHAARATHYTNGGNMGNTAY GAYATHGTNYTNYTNCARGARACNMGNGAYGGNACNGGNACNGCNYTNAARGAYYTNAAR GARAARYTNAGYTCNGCN---GARTCNTGGGAYTAYGTNGCNAGYGGNCARYTNGGNAAR AGYAARGCNTAYYTNGARCARTAYGTNTTYTTYTAYMGNGTNAARTCNGCNACNYTNGTN ACNACNTAYCARATHAAYGAYACNGCNAAYGAYYTNTAYGCNMGNGARCCNTTYTGYGTN GARTTYGCNTAYACNTCNGCNTCNCCNATHCAYMGNGARAAYGTNGTNYTNYTNGCNYTN CAYGCNCCNCCNGARGARGCNMGNAARGARYTNGARGARYTNCCNAAYACNGTNAARTTY GTNGCNGCNYTNTTYCCNCAYTCNGCNGGNGTNATHGCNATGGGNGAYATGAAYGCNGAY TGYMGNTAYYTNGCNGGNAARTGGMGNAARTCNYTNAARATHTTYAAYGGNGARGGN--- TTYAARAGYYTNATHCCNGAYTCNGCNGAYACNACN---AARGGNAGYTCNGAYTGYGCN TAYGAYMGNGTNGTNYTNTAYGGNGAYGGNYTNGAYGTNTCNGAYGCNAARGTNTTYGAY TAYCARTCNTGGYTNGGNYTNGAYGARGCNGGNGCNYTNAAYATHAGYGAYCAYTTYCCN GTNGARTTYGTNYTNCAY---TTYAGYATHAAYYTNTGYGTNGGNCCNACNTAYGAYCAR GAYTGYGCNYTNCAYTTYAAYCCNMGNGTNGAYGARAAYMGNGTNGTNMGNAAYCAYATG CARGGNGGNAGYTGGGGNAGYGARGARACNGCNGGNGGNTGYCCNTTYAARAARGGNCAY CAYTTYGARYTNCAYATGAARGCNCAYMGNCAYGGNTAYCAYATHGCNGTNAAYAAYMGN MGNTTYTGYGARTTYAAYAAYMGNYTNCCNMGNACNAGYATHCARTAYATHTAYATHGAR GGNGARGTNATHATHAAYTAYATHAAYTTYAGYGGNGGNCCNTCNTTYCCNTCNCCN--- ---CCNAGYGGNCCNGGNTTYCCNTCNGCNTTYCCNGGNTAYCCNCCNGCNCCNAGYTTY CCNTCNGTNCCNAGYTAYCCN------TCNTCNTAYCCNGCNGTNYTNGGNTAYCCNGGN GGNGCNTTYGGNCCNATHTAYAAYCCNCARGTNCCNTTYACNACNGCNATHCARGGNGGN GTNACNCCNGGNAARATHGTNTCNATHTCNGGNGTNCCNCAYCCNAAYCCNAGYMGNTTY ACNGTNAAYATGCARTGYGGNCCNTTYGAYTCNGGNGAYATHGCNATGCAYTTYGAYGTN MGNTTYAAYTAYGGNAGYGAYCAYAAYCARGTNGTNMGNACNCAYAARYTNGGNGGNACN TAYGGNAAYGARGARAARCARATHACNCAYTTYCCNTTYTAYCCNAAYACNCCNTTYCAR ATGATGATHYTNATHGARACNTCNTCNTTYAARATHGCNGTNAAYAAYCARCAYTTYGTN GARTTYTAYCAYMGNATHCAYCCNTTYAAYMGNGCNGAYCAYATHAAYATHAGYGGNGAY GTNMGNYTNACNGARGTNMGNTTYCARACNTCNGGNTTYGTNCCNAAYTTYYTNGTNAGY TCNGGNACNGGNYTNACNCCNACNYTNACNCCNACNACNYTNGCNACNATHGARCARTCN TTYATGGARYTNCARCAYTCNGGNGCNMGNGAYCCNGTNACNCARAGYGGNTTYGTNCCN CCNGTNGTNGARCCNTCNAAYAGYAAYAGYGCNGAYCARTCNCARGAYAGYTAYGAYAAY TCNTCNTCNGAYACNGARTGGGARCCNAGYAGYAARMGNYTNTGYATGAARGAYGGNGTN AARGGNGTNGAYTAYATHGTNACNTCNACNGGNACNGTNAAYGTNGCNCCNCARMGNAAR TAYACNMGNMGNAAYAARGAYGARAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GTNTCNGARATGTCN GGNCARATHGARMGNYTNGARTCNATHATHTCNGAYGCNGAYAARTCNATGTGGCARCAY GARTGYAGYGCNYTNGARTCNYTNAARGTNCARCAYAARGAYYTNACNTGYGTNYTNGAY AARACN------------ATGGTNGARCARGTNAAR---ATGAARYTNTTYMGNACNMGN AARMGNAARGTNMGNMGNAARMGNTCNGGNCARGCNCARGARGTNGARGARGCNMGNCAR GCNAARGARMGNGARATHAGYGAYTGGCARCARMGNATHYTNTCNGTNATGAARGARGAY YTNATGAARMGNAARMGNAARGARCARATGGAYCARACNYTNAGYGARGTNACNAARAAR ATHAAYGAYGCNAAYMGNYTNGTNGAYACNATGACNGCNYTNGARAARYTNMGNYTNATH MGNCARGAYGCNGCNAARAARMGNGGNGAYAGYGAYYTNGGNGARTCNMGNGARAGYTTY GARCARAARATHGAYGAYATGACNMGNYTNGTNGGNTCNCARYTNGARGTNTAYMGNGAR GARGARGARYTNYTNMGNAGYGTNATHAARTCNGARCARGARGARACNAGYAARAARGAR MGNCARYTNCARGCNATHAARGAYMGNGARGARCARMGNCARAARGAYGAYGAYGTNAGY AARATGYTNTTYGGNATGGARAARGAYATHGAYGAYYTNYTNGAYGARGTNGARTCNAAR TAYGTNAAYMGNTCNMGNAARACNGARAAYYTNTCNATHTCNCCNACNCCNAARCAYMGN ---------------ACNACNGTNGAYGAYGAYATHAGYGAYATHYTNGAYYTNGAYYTN GARGAYGGNGTNACNCCNAAR------AARGGNACNCCNAARAAYAAYACNMGNACNGTN CCNCCNACNGGNGAYMGNAARGAYGCNACNAARAARTGYTTYCCNATHTTYYTNGGNGGN AGYAAYGAYGARACNGGNYTNGGNACNACNGTNAARACNMGNGCNTGYGAYCARYTNMGN TGYACNGAYTGYGAYTTYMGNGTNTGYTGYTTYGAYGARTTYTCNTGGAARAARGAYACN AAYTAYYTNTTYYTNMGNAAYAAYGTNCCNGAYTTYGARAARYTNAARTCNAAYYTNMGN MGNCARAARGGNTGYMGNGCNTAYTGYTGYCARTGYACNTGGAARGAYGTNACNACNYTN CARGARATHTCNGAYTCNAARYTNAARTGGGTNTGYGGNAARCAYGAYTCNCCNGCNAGY GTNATHGARGCNYTNATHTGYTTYTTYTCNATHTGGTCNGTNGTNGGNYTNGCNGGNTTY CAYTCNTAYYTNACNGCNTCNGARATHACNACNAAYGARGAYATHAARGGNACNTTYACN TCNAARMGNGGNCARGAYAAYTTYAAYCCNTTYAGYAARGGNTCNYTNTTYAGYAAYTGY ATGGGNATHYTNTGYGGNCCNGTNCCNCCNAGYYTNYTNGAYMGNMGNAARYTNATHGTN CCNGARYTNGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNGARTGYCCNTAYAAYCCNTCNCAY ATGATHTGYCCNYTNMGNATGCCNTAYCAYYTNCAYMGNTGYMGNAARAAYTAYCCNAAY YTNGTNATGTCNGTNTGYCCNTAYAAYGCNATGCAYGARGTNMGNACNCCNGARYTNAAR TAYCAYATGAGYCARTGYCCNAAYMGNACNYTNYTNGARMGNGAYATGCCNTAYAAYGCN YTNCARAAYGCNYTNYTNGGNAARGARGARAARGARGTNAARGGNAAYACNGAYYTNCCN CAYCCNGCNMGNATHCCNMGNGGNGAYGAYGAYAAYYTNGARAAYTGGGAYCARGAYGTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARGCNGCNGTNTCNGAYGCNGGNGGNATHAAYACNGCNYTNGTNAAYGTN TGYMGNMGNTGGACNGGNYTNAAYCARCAYACNMGNATHATHYTNATHAGYGAYGARAAR AARGAYATHAARTCN---------YTNACNAARGARAAYAGYACNGTNCAYCARAGYYTN AARGARYTNTCNATHAARGTNGAYCARCCNATHTAYATHATHAARACNGCNAARAGYCAY ACNAAYAGYTTYTGYYTNCCNCCNCARCCNGGNGTNYTNGCNTTYYTNCARACNMGNCAY TTYYTNAAYYTNCAR------CAYTCNGTNTAYGTNATHGARACNACNGAYCAYATGAAR GTNGCNCARGCNGCNGGNGTNAARTTYGTNAARAGYAAYAARGCNTTYMGNTAYCCNGAR AARGCNYTNAGYAGYYTNTGYATHYTNCCNCCNATHCCNGTNATGYTNMGNGAYATGTCN GARGTNAAR------GGNGARATHACNACNGCNGTNTGYYTNCCNYTN---YTNGAYAAR TGYGTNGAYAGYGAYTGYGGNTTYGCNACNCARATGCAYCCNTGYGGNTTYGARGARYTN GTNTTYGCNCCNGAYGTNACNAARACNYTNAAYATHCARGARATHTTYGCNAGYYTNGTN ACNCCNACNGAYATGCCNGGNAGYAARYTNAARGTNAARGARGCNTCNGTNGGNGAYAGY GTNGCNTGYACNAGYGCNGCNMGNGARAARCCNCCNGTNGARTGYAARAAR------GAR GGNTCNAAYCAYMGNYTNCCNGTNTGGATGACNMGNMGNTCNAAYMGNAARTCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TAYCARGCNATGATGACNTAYTGYAAYCAYMGNACNACNMGNTGGAAY YTNTGGAAYGCNTAYCAYAAYMGNGCNTCNCAYGAYCAYGCNAGYCARTAYYTNAAYAAY AAYAARYTNATHGARAGYYTNMGNTCNTTYMGNTCNGAYGTNGCNACNATGGTNGGNTAY GAYAAYTTYGCNGARATGTCNATGGARACNAARATGGCNGGNTCNGTNGARAAYGTNYTN AGYATGATHGARACNYTNMGNGCNMGNTAYGCNCCNGTNGTNTGGGARGARATHGCNGAR YTNCARGAYTTYGCNACNTCNGARGGNTTYAARAAYTCNYTNGARACNTGGGAYGTNGGN TAYTGGMGNMGNMGNCARMGNGAYCAYYTNTAYAARGTNAAYATGGAYGCNGTNAARGAR TAYTTYCCNATHAAYACNGTNYTNYTNGGNYTNTTYGAYYTNTGYACNAAYYTNTTYGGN GTNAAYTTYGARGARGTNACNCCNGAYGTNGARGTNTGGCAYCCNGAYGTNMGNTTYTTY AAYGTNYTNGAYGGNGARAGYGGNGARCAYATHAGYTCNTTYTAYTTYGAYGCNTTYGAY MGNCCNGGNAARATHTCNTCNGGNTAYATGAAYYTNGGNMGNGAYAAYAGYGARCAYATH GGNACNTGGCCNTAYTCNTAYYTNTGYYTNMGNACNCCNMGNCCNAARTCNTCNTCNGAY CCNGCNYTNATGMGNTTYGARGAYATHGARACNYTNTTYTCNCARTTYGGNCAYGGNYTN CARCARATGYTNACNAARGTNCCNTAYAGYGARATHGCNGGNCARAARAAYATHGARTGG GAYGCNGTNMGNGTNTGYTCNCARTTYATGAARYTNTGGYTNACNAGYCCNGCNGTNGTN AARAGYYTNAGYAGYCAYTGYAARACNGGNGARACNATHCCNGAYGAYATGYTNTCNAAY ACNYTNAARGCNTCNCARCAYGGNAGYAAYTTYGAYACNATGAAYCARYTNTAYGTNGCN GCNTTYGAYYTNGARATGTAYATGACNAARACNCAYTGGTAYACNGTNATGMGNCARYTN TGGGARAAYTTYATHCCNYTNCCNTTYAAYGARGARGAYAAYYTNCCNTGYTCNATGYTN CCNATHTTYTGYGARYTNTAYCCNGCNGCNTAYTAYTCNCARAARTGGTCNGARATGATH GCNGCNGAYATHTTYTCNGCNTTYCARGARGCNGGNYTNGARAAYCARGARAAYATGMGN GTNYTNGGNAARMGNTTYAARGAYACNTAYYTNTCNYTNGGNGGNGGNGTNCCNTCNTGY GARGTNTTYMGNCARTTYMGNGGNMGNGAYCCNTCNACNCARGCNYTNCARCCNATGGAR AAYAAYAAYGCNATHGCNACNGAR---CCNGARGAYGGNGAYGCNAARATHGARAAYGTN AARCCNACNGCNGCN------GARGARGARAAYGAY---------GCNTCNCCNGGNMGN YTNCARCARATHMGNMGNGAYGCNAAYGCNGARACNGARACNGGNAARGCNGCNATHMGN MGNAARATHTGGGAYAAYYTNGARGAYAAYAAYYTNGTNTCNGTNCCNMGNCCNTGYCAY TAYMGNATHCCNAAYTTYGARGGNTCNTCNGARGCNGCNGAYMGNYTNACNTCNYTNGAR GARTTYAARAARGCNCARACNATHAARGTNAAYCCNGAYAARGCNCARGARCAYGCNMGN TTYYTNGTNYTNGARGCNGARAARGAYYTNGTNYTNYTNAAYCARAAYCARAARGARYTN ATGGTNCCNACNGARCARYTNAARTCNGGNYTNYTNAAYMGNATHGTNCCNCCNGARGGN GCNAAYAARGARGARYTNMGNCAYTGYTGYACNACNCARGGNGTNAARGARAAYAGYAAR GARATHAGYAGYGGNGAYAARGTNAARYTNGAYYTNATHGTNGTNGGNAGYGTNGCNGTN TCNMGNAAYGGNTAYMGNATHGGNAARGGNAARGGNTAYGCNGAYYTNGARTAYTCNATG ATGMGNACNYTNGGNGCNGCNGAYTCNAAYACNGTNGTNGTNACNACNGTNCAYGAYTCN CARGTNGTNGAYATHGAYGAYGARYTNGTNGGNGARCAYGAYATHTCNGTNGAYTAYATH YTNACNCCNACNGARYTNATHAARACNAAYAGYAARMGNACNCARCCNTCNGGNGTNATH TGGAAYCAYYTNYTNGTNAAYAARTTYTAYCARATHCCNGTNYTNMGNCARYTNMGNAAR AAYGARMGNGAYGAYGGNAARGAYGTNYTNYTNAARGAYCARAARGARGARGAYGARGAY CCNGTNGAYGCNATGGARCCNCCNCARCCNMGNMGNTAYGTNMGNTAYTAYAARAAYGAY AGYGGNTAYMGNGGNMGNGGNMGNTAYTAYGGNGGNMGNTAYMGNMGNGGNGGNMGNMGN MGNCARTTYGAYGAYAAYGGNGARGAYTCNGGNGCNGAYGGNGAYAAYGARGGNGGNMGN ATGGGNGGNGGNGGNAAY---MGNMGNCCNCCNCCNMGNAAYAAY--------------- AAYTAYMGNAAYMGNMGNTTYMGNMGNGGNGGN---------AARGCNMGNGTNTCNGAR TCNGARCAYAGYGAYGGNGGNAAYCAYAARGAYGGNGGNGAYGGNGARGAYMGNCCNMGN CARGGNMGNTAYAAYACNAAYMGNMGNMGNTAY------------ACNMGNMGNMGNMGN TTYGAYAAYMGNMGNGAYAAYMGNMGNGAY------------GAYCAYTCNGGNAGYGAY GGNGARCARAARTAYTCNGCNGAYGAR---GGNGARGGNMGNMGNCCNCARMGNATGMGN TTYMGNACNAAYCCNGARGCNGTNGTNTTYGTNGGNTCNYTNTCNMGNAAYYTNMGNGTN AGYGARYTNAARGCNGARYTNMGNAGYCAYAAYGTNAGYCCNYTNMGNYTNYTNTGGMGN GGNGCNAAYGGNTAYGCNTTYYTNTTYTTYATGGARCCNGAYAAYGCNAARCARGCNGTN GGNGTNYTNTCNGGNMGNGARYTNAAYGGNMGNGARATGAARGTNGARATGGCNAAYATG GAYMGNGAYMGNMGNMGNTCNAAYMGNAAYGAYMGNGGNMGNGARGARGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARCARMGNATGGARCARMGNCCNCARGAYGTNAGYGAY YTNGARMGNCARTAYYTNGCNCARTGYACNAGYGARGARCARMGNCARGCNYTNATHGCN TCNGGNGCNTTYGGNAAYGAYTCNACNGCNATGGCNGCNYTNAGYGCNTTYTAYGGNCAR YTNGGNGTNGARATHGCN------------------------------------------ ------------------------------------------CCNCARTTYCAYGCNTAY GCNTGYGARCAYATGGTNGAYTTYCCNATGMGNGARGAYGAYGTNYTNYTNGTNACNTAY CCNAARACNGGNGTNCAYTGGTCNTGGGARATHYTNMGNATHYTNGTNACNGGNGAYATH GTNAGYAARGGNYTNGAYAARGTNAGYTAYATGATGGARTGGMGNCAY---CCNGAYGAR TTYCARACNYTNCCNGCNCCNMGNGTNYTNAAYAAYCAYATGCCNTTYCAYCARCARCCN AGYGAYYTNYTNAARAARAARCCNAARGTNGTNYTNTTYTAYMGNAAYYTNAARGAYGTN GCNGTNTCNTTYTAYCAYCAYCAYTGYGGNATHAARGAYTAYGGNTAYCARGGNGGNGAY TTYGGNGCNTAYYTNGAYMGNGTNATHGAYGGNYTNATGGARTCNGGNAAYCCNTTYAAR TTYCAYAARGARTGGGAYGARGCNATHAARAAYCAYCCNGAYYTNCCNGTNTAYTGYTGY GCNTTYGARGAYATGAARGAR--------------------------------------- ------------------------------------------------------------ ------------AAYCCNGTNTCNGARATGMGNAARATHTGYGAYTTYYTNGGNAARTCN TAYGAYGARGAYTTYYTNCARGARGCNGCNAAYACNACNAGYTTYGAYAAYATGAARAAR ACN---------------AAYGGNGCNTCNAAYCCNGTNTTYTTYMGNAARGGNCARGTN GGNGAYTGGAARAAYCAYTTYACNGTNGCNCARAAYGARTGGTTYGAYAGYYTNATHCAR TCNGARYTNGCNGGNACNAGYTTYAARTTYMGNTAYTCNYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARAARYTNACNGARATHMGNGAYMGNGTN GARACNAARYTNAARGARTTYGARGGNYTNCARGAYMGNTTYCCNAARGARGCN------ ------GCNGARGARGGNCARMGNGCNTGGGCNGTNAAYTCNAAYTTYTCNACNGCNCCN TCNTCNCCNGCNAAR------------------CAYAAYCAYMGNGCNTTYCCNCAYGAY ACNAAYACNYTNYTNAGYGARGAYGARGAYGAYCCNYTNMGNGGNYTNCARMGNATHAGY GAYATGAARCCNTCNAGYCARTGGTAYGGNAGYYTNTCNATGGARCCNGAYGAYYTNAGY GTNCAYATHGAYMGNAAYGAYMGNAGYGGNATHCARACNTAYYTNCAYAARGARGGNYTN GTNATHGCNMGNGCNAARACNTTYYTNCAYAARCARMGNMGNACNYTNAARCARMGNCAR TCNGCNYTNAGYGCNGCNAARAARGARYTNAAYAARGAYAGYAGYATHYTNCARCARTCN AAYCCNACNAAYGARGCNACNGARATGYTNGGNAARGTNMGNGAYACNYTNGARTCNGAR ATGGTNCARATHGAYGCNYTNCARTCNAARTTYGAYTCNGAYTCNAARYTNYTNAARGAR AARGARGARAAYTAYCAYMGNYTNGARGGNYTNGCNAARGARAAYGARAGYGAYGAYGAR TCNGARTTYAGYCCNTTYGGNMGNCCNTTYCAYGGNGTNAARATHCCNAAYATHGAYYTN AGYGARGAYGARAGYAGYGGNGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARATHAGYAARTCNAGYACNATHCARCARGARATHGTNYTNGAYGCNGGN AGYCCNTAYYTNMGNTTYAAYACNACNGTNTCNTGGCARGARAGYCAYAARATGYTNAAR GTNGARTTYCCNACNTCNATHCAYTCNATGGCNGTNTCNTAYGAYATHCARAGYGGNTTY TTYAAYMGNCCNAAYCAYTTYAAYACNTCNTGGGAYTCNGCNMGNTTYGARGTNTGYGGN CAYAARTGGGCNGAYATHTCNGARCAYGGNTTYGGNGTNGCNATHYTNAAYGAYTGYAAR TAYGGNTAYTCNGCNGTNGAYGGNATHATHMGNYTNTCNYTNYTNMGNTCNCCNAARAGY CCNGAYCCNCARGCNGAYATHGGNYTNCAYACNTTYGCNTAYGCNATGATGCCNCAYGTN GGNAAYYTNCARGARTCNGGNGTNATHCAYGARGCNATHGCNTTYAAYAGYCCNYTNAAR ACN------------GGNAGYGGNYTNTGGGGNACNGGNATGGARYTNTCNCCNYTNTTY GARTGYAGYACNGCNCARGTNGTNGTNCARACNGTNAARATGGCNGARGAYMGNAGYGGN MGNGTNATHYTNMGNYTNAAYGARGCNTTYGGNGGNAGYGTNAARGTNGAYATHGTNTCN GGNGTNAARTTYTCNGAYATHAARYTNTGYAAYGGNYTNGARGAYCCNATHGARGAYGAY GGNATHYTNTCNTCNYTNAARTCNGGNACNGGNAAYGGNAAYGGNACNTTYTCNYTNACN YTNAARCCNTTYCARATHGTNAGYYTNMGNTGY------GGNMGNTAYYTNACNGCNGGN AGYAAYAARAAYGCNGARGGNMGNATHCAYATGYTNCCNCCNGAYCARTGYGGNAARGAY GAYGTNAARGGNTTYGCNMGNYTNCCNCARGAYTGGGTNGGNGTNYTNCARTAYTCNACN GAYACNGARGGNATGGGNGGNGAYACNGGNACNTTYGAYTGYCCNYTNGTNYTNGAYMGN GTNAARAARGCNYTNATGTTYGGNGCNTCNGCNATHATHATHYTNACNYTNAAYCARMGN GTNGTNAARGARYTNGAYGCNTCNCARATGGTNTCNAARCCNGTNGTNYTNATHGAYGAY YTNGARAAYATHACNACNTTYYTNACNYTNYTNYTNAGYCAYGTNAARYTNCAYGGNAAR ATHATHATHAAYAGYAARGCNGAYCCNAAYCARYTNTGGCARTGYTTYTAYGCNATHGTN YTNTTYYTNGTNATHYTNATGGGNGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARGARAAYAARGAYTCNACNGARCARATHCAYAGYGARYTNGCNGCNYTNYTNAAR TGYGARTAYGARAAYATHGTNACNYTNTAYGGNTAYTGYYTNGAYGGNYTNGARYTNTGY YTNGTNTAYCARTAYYTNAARAAYGGNTCNYTNGARGAYMGNYTNATGMGNAARAAYAAY ACNCCNTCNYTNTCNTGGGARMGNMGNYTNAAYATHYTNGTNGGNTCNTGYAARGCNATH AGYTTYYTNCARACNATGTGYACNCCNTCNYTNATHCAYGGNGAYATHAARAGYGCNAAY ATHYTNYTNGAYGGNCAYATGGARGCNAARTTYGCNGAYYTNGGNCARTCNMGNTAYGCN ACNGGNGGNAGYACNAAYACNGGNAGYYTNACNCAYATHACNATHGCNCARTCNACNAGY MGNCARTAYGGNACNACNGCNTAYCARGCNCCNGARATH------AARTCNTGYTGYAGY ATHTCNACNCAYTCNGAYATHTAYTCNATGGGNGTNGTNATGYTNGARGTNTGYAGYGGN ATGYTNGCNTAYGAYTAYAGYMGNAAYGARAAYAARTTYYTNACNGAYTTYTAYGARGAY TAYTTY---GCNAARYTNAGYGARCCNAAYMGNGTNCARGARTTYCARGAYAARACNGCN CCNGAYTCNATHCAYCCNACNGCNTTYTCNTCNGTNYTNAARYTNGCNGGNCARTGYATH AAYGARATHAARAARGCNMGNCCNAGYAGYGGNAARYTNGTNAARACNATGAARAARATH TAY--------------------------------------------------------- ---------YTNCARMGNGGNAARGGNGTNTCNYTNACNGGNATHATHAGYATHGCNAAR AAYYTNCARMGN------GARAAYGGNAAYGGNYTNAGYYTNGARGAYMGNATGTCNGTN GARCARTGGYTNGAYTTYAGYGCNGARATHTCNAGY------------ATHGARAAYGTN AGYGAYMGNGARMGNATHGGNTCNGTNYTNAARGAYYTNAAYAGYTTYATGAARGAYMGN GTNTAYTTYGCNGGNGTNACNGTNACNGTNGCNGAYGTNTTYYTNTAYCAYAGYYTNTTY TCNATHTTYGARMGNATGTCNTTYCAYGARAARGARCARYTNATGCAYYTNTCNMGNTGG TTYAAYYTNATHCARAGYGAYGGNAARGCNMGNCARTCNYTNTCNYTNGTNAARTTYYTN MGNACNCARATHTAYTCNAGYATHGGNCAYCAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AAYGAYTGGYTNATHTCNGCNTTYAAYGTNGAYAARGARTCNYTNTCNCCNATH GARGCNACNCARATHTTYGTNAAYAAYAAYTCNCAYGTNYTNGARGTNGAYTTYGARCAR TCNAAYYTNGCNGARGTNTGGAARACNATH---ACNGCNTTYATHCCNAARGAYTCNMGN ATGAARAARGAYMGNACNTGYTTYTCNACNCARGCNATHMGNACNTCNAGYTCNGARAAR ATGMGNYTNMGNYTNGARTGYAGYCAYTCNGARYTNAARGARYTNATGAARGGNGTNATH ACNTGYCARACNGTNGARAARTAYTCNGTNAGYYTNYTNACNAARGTNCCNGARAGYAAR TGYGGNATGGGNMGNAARGCNAAYYTNGCNGARCCNATHACNYTNGAYGARGCNGTNGAR TCNGTNAARAGYCAYYTNGAYYTNAARCAYGTNAGYYTNGCNAARGTNCARGGNTCNGAR GAYAARATGATHGARACNGTNGCNGTNTGYGCNGGNTCNGGNTCNAGYGTNYTNAARAAY GTNAARGCNGAYYTNYTNGTNACNGGNGARATGTCNCAYCAYCARATHYTNGAYGCNGTN CAYGGNGGNAGYAAYGTNATHYTNTGYCAYCAYAGYAAYTCNGARMGNGGNTTYYTNAAR GARYTNCARAARMGNYTNAGYAARGTNATGGARAARCCNGTNCARGTNTTYGTNTCNGAR GTNGAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ATGGAYYTNTTYMGNTCNTGG YTNTAYGGNMGNGARAARCCNGARMGNAARACNGTNACNGARAAYGARAAYGGNGCNCAR AAYATGGAYCARAARACN---------------------------TCNACNYTNGARAAY YTNGTNYTNAARGTNGTNCCNYTNGARCCNGGNGAYTGYYTNGGNTGYAARYTNGTNGGN ACNTCNGTNATGATHGTNAGYGGNTTYATHGTNYTNACNTCNGCNATGGCNGGNMGNAAR MGNYTNTAYGTNGAYGAYTTYYTNGTNTAYMGNAGYAARTCNAARATGGAYGCNATHGAR MGNCARYTNCARYTNCARYTNAAYAARYTNAARGARTGGGCNGAYYTNAAYGGNTTYAAR TTYTCNCCNTCNAARACNGTNGCNGTNCAYTTY---TGYMGNAARCAYMGNTGYATHMGN GARCCNGAYYTNTAYYTNGAYAAYMGNMGNATHAARGTNGARGAYMGNGCNMGNTTYYTN GGNGTNATHTTYGAYAARAARYTNAAYTTYYTNGCNCAYATHAARGAYYTNMGNYTNMGN TGYATGAARGCNYTNMGNGTNATGAARGTNYTNTCNAGYAARGARTGGGGNTCNGAYACN AGYACNYTNYTNCARATHTAYMGNACNYTNATHMGNTCNAARYTNGAYTAYGCNTCNTTY GTNTAYGGNTCNGCNAARCCNACNTAYYTNGGNATGYTNGAYCCNATHCAYCAYCARGGN YTNMGNYTNGCNYTNGGNGCNTTYMGNACNTCNCCNGTNGARAGYYTNTAYGCNGARGCN GAYGARCCNCCNYTNAARATHMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATH GARYTNCCNGCNCARYTNGARGCNCCNCCNATHYTNCAYMGNATHACNAAYGCNCARGAY TTYAAYCCNGGNTTYAARAARTTYTGGAARAARYTNTTYYTNTCNGARGCNTCNTCNGCN GTNYTNCARGAYGCNTTYTGGTGGATHTTYYTNGAYATGTTYAAYAARACNGARGGNTTY GARGARGAYAARGAYTGYATHTTYGAYMGNATHGCNGAYAGYTAYGTNGCNYTNTTYACN AGYATHAAYACNGAYGTNAARGAYAARTTYYTNTCNGTNTAYCCNAGYTGYYTNTCNCAR GCNYTNTAYTAYACNTAYMGNGARGCNTTYCCNGARTCNAARTGGMGNTTYGAYGARACN TTYAARCARTAYYTNGTNAAYYTNATHTAYGARTGGGTNATGGGNYTNMGNCCNGTNCCN GGNGTNTGGAARGCNTGGAGYGARGARGGNYTNGARGGNAAYCARACNAGYMGNGARAAY GARACNGCNAARAARATGYTNGARGCNGCNGCNYTNAAYAARAARGTNGARYTNAGYYTN GAYATGGARTCNTTYGCNAARGTNATHGAYAARYTNGGNACNGARCCNGAYGCNACNCCN CARGGNCAYATGTCNMGNGARATHACNAARACNAGYAAYMGN------ATHTCNGTNCCN TCNMGNGGNMGNGTNAAYYTNYTNAARCAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GCNAARAAYYTNAARGCNGCNTGYCCNTGGAGYTGG ACNTTYGAYACNTGGACNAAYGTNTAYCCNMGNTAYGTNAARCARGCNAARTGYATHTGY GARMGNTGYGTNAAYGCNMGNTCNATGGGNTCNAGYAAYYTNAAYMGNAARTTYCARTTY TAYCAYAARACNGGNTGY------------------------------------------ ------------------------------------TAYGAYCCNAAYTAYTTYTCNATG CCNCAYCCNGCNYTNGGNGCNTTYACNATHAGYYTNYTNATHTAYYTNTAYGTNACNACN GTNACNCCNAGYAGYYTNCCNGAYTTYYTNTGGCCNTTYGCNCARATHGGNAARTAYATG TCNAGYCARCAYTTYAAYGTNGTNATHGGNTTYTGYGGNTTYACNYTNATHGCNCAYTGY YTNGARGCNGCNTAYGCNGGNAARGTNTGYCARGAYMGNMGNTAYTCNGTNTCNACNACN ATHAARTGGGTNYTNTCNACNTTYACNTTYGGNTTYCCNTCNATGATHMGNYTNYTNTCN GTNAARCCNMGNTCNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GAYMGNATHYTNGARGAYMGNGARMGNTTYGARGAYCAYYTNMGNAARMGN TCNCAYCAYCCNACNGGNAARTTYGAYCCNTGGACNYTNATGGARGARATHTCNGARGAR ATHYTNAARGARTGYYTNCARGARGTNTCNGARGARGTNGARAARGTNAGYGARGARATH GCNAAYCARATGTAYAARTCNGARTTYATG------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TCN GAYGTNAAYACNCARGAYYTNGAYCAYGAYACNCCNYTNATGTTYGCNGCNTGGAAYAAY GCNCCNACNATHATHTCNGCNYTNATHCARCAYGGNGCNGAYGTNAAYMGNAARAAYAAR TAYGGNAGYACNTCNATHTGGAAYGCNGTNTAYCARTCNTCNGCNGARTGYGTNYTNATH YTNYTNACNAAYAAYTCNACNATGGAYGCNCCNTGYGARGGNACNGAYYTNTTYTTYAAY GAR------GGNGAYTAYCAYGARNNNAARATHACNAARYTNTAYCCNGGNTAYAARMGN TCNYTNYTNTGGGTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GARMGNGARMGNACNMGNGAYTTYGAYMGNMGNMGNYTN GCNGARGGNTGYTCNGGNAARGTNATGGAYATHTTYTTYYTNATGGAYTCNTCNTCNTCN ATHTAYATHAAYGAYTAYATGTCNCARCAYMGNYTNGTNMGNGAYATHATHAGYMGNTTY GAYGTNAGYAGYGARTCNACNMGNGTNGGNATGYTNACNTTYAGYGAYGAYYTNGARMGN CCNGTNATHTCNYTNAAYCARTAYAGYGGNAARGCNGARYTNYTNTCNAGYATHTCNGTN CARAAYYTNCCNTAYMGNACNGGNGTNACNAAYACNGAYATGGCNATHMGNTAYGTNMGN CARYTNAAYAAYTTYMGNCARGAYATHACNAARGTNATGGTNGTNATGACNGAYGGNGGN TCNMGNTCNCCNGGNTCNACNGCNMGNGARGCNGARYTNGCNMGNAAYGCNGGNTTYTAY ATGTTYGTNGTNGGNATHGGNCARTAYATHGARGARMGNGARTGGMGNTCNATHGCNAGY GAYCCNGAYGAYAGYTTYGTNTAYAAYATHACNTCNCCNMGNTTYYTNGAYGARGTNCAR TTYTCNYTNCCNCCNMGNGCNTGYGAYYTNCCNCCNATHATHYTNGGNGGNTCNTGYGAY GTNTCNMGNATGTCNGARGTNTAYTTYGTNGCNGGNMGNACNGCNCARGAYTCNGTNCAR AAYTTYYTNGAYAAYTTYGGNMGNMGNACNMGNGAYCARMGNGAYYTNYTNMGNGTNAAY TTYYTNATHGAYGGNTGYGTNCCNGTNACNGAYATHCARYTNYTNAAYGARGAYCCNTTY ATHTGYGARMGNTAYGAYMGNCARGGNAAYGCNGTNYTNGCNMGNGGNTCNGCNGARATG TTYGCNGARGCNGTNMGNGCNYTNMGNGARAGYMGNGAYTCNGARACNAAYCAYGTNATH GTNYTNTTYGCNGAYGARGARACNATGAGYTCNGAYMGNTTYGAYYTNGCNAAYAAYGCN MGNAAYGCNCARAAYTTYGARGGNGCNAGYGTNGTNGTNGCNGAYYTNGGNATHMGNACN TAYMGNGAYTTYGCNCARMGNATGGCNTCNGGNMGNAAYAAYTTYATHAGYTTYACNAGY GGNAAYTTYGCNGGNCARTCNAAYGCNCARMGNAAYYTNYTNGAYTCNATHTGY------ ATGGCNGAYAGYACNAAYCAYCCNGAYYTNYTNTTYGAYAGYCARCCNGARAGYTCNGGN TTYACNAAYGAYGAYTTYGARAARGTNGAYGCNCCNGGNGGNGGNTTYGGNCAYGAYGAY GTNACNGCNGCNGCNGCNGCNGCNTAYGARTAYGAYGTNAAYCARGAYGCNGARATHTCN ACNACNGCNGAYGCNGAYTTYGARGGNGARGARGARGCNGARGCNGAYMGNTTYGCNGTN ---------------------------------------------------TCNMGNGAY GAYGARCCNGCNTAYCCNTCNTGGGGNGAYGARGTNGARGAYAAYGAYGAYATHACNGCN CARGTNCARCCNTCNGCNCCNGTN------CCNGARAAYAAYGAYCCNYTNGTNAAYTTY GAYGAYAGYTCN---TCNGGNCAYGAY---TAYTTYATGCCNTCNGTNCCNTCNAGYGAR ACNCCNAGYAAYYTNYTNCARACN---CARYTNGAYGARATHATHGARCCNAARMGNGAR GARAGY------------------------------GARAGYGTNAARGARAGYAARCAR GAYTCNGAYCCNACNCCNGTNGCN------TCNGCNAARGGNTCNTGGYTNAARGGNGTN GAYCCNMGNAAYACNGAYATHGAYGAYTCNTTYTCNAAYGTNYTNATHGAYYTNATHTAY TGGMGNGAYGTNAARACNACNGGNATGGTNTTYGGNGCNATGTTYGTNGTNYTNYTNTCN YTNGCNATHTTYTCNYTNATGAGYGTNGTNGCNTAYYTNTCNYTNGCNGTNYTNGTNGTN ACNTTYAGYTTYACNGTNTAYAARAARATHATGGGNGCNGTNCARAARTCNAAYGAYGGN CAYCCNTTYAARCARYTNATHGAYATGGAYATHACNYTNAGYGARGAYAARYTNAARAGY GTNATHCARAGYATHYTNAARAAYGTNAAYTGYACNATHAGYGARYTNMGNMGNYTNTTY YTNATHGARGAYATGGTNGAYTCNATHAARTTYGGNYTNYTNYTNTGGGTNYTNACNTAY GTNGGNGCNTGGTTYAAYGGNATGACNYTNATHATHYTNGTNGTNATHAGYATHTTYACN YTNCCNAARGTNTAYGARACNTAYAARGTNCARATHGAYAAYTAYATHGCNATGGCNAAR GCNCAYGTNGAYAAYGCNATGACNATHGTNCARAGYAARYTNCCNTTYYTNAARAARAAR GARAARGCNCAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GGNTAYTTYAAYYTNACNGAY GARTAYGTNGAYGTNATHGTNAGYGAYGCNGAYTCNAARTTYAAYATHYTNATGGCNTCN CCNAARGCNAAYGGNTTYYTNGGNGCNAARGGNATHGCNGGNGCNGTNGCNTAYTCNTAY ATHTAYYTNGCNCAYCARTTYTAYAARAARGTNTCNAARGCNCARCARTCNCAYMGNATH AAYATGATGGARTAYGARMGNGARGGNTGGACNTTYCAYAGYAARGGNYTNTGGTAYTAY YTNAARAAYGAYCCNYTNCCNMGNYTNACNYTNATHGGNTCNCCNAAYTTYGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MGNGGNTAYCCNGGNCARMGNCCNGARAAYMGNGARACNTAYCCNGGNGAYGAY GTNMGNMGNTCNGARATHCCNTCNTCNCARGCNGAYCARGTNGTNGCNGGNGAYAGYGTN ATHCARMGNCCNYTNACNGAYTCNAAYTAYGTNMGNAARAAYYTNACNGAYAGYGGNCAY GCNATGYTNYTNTCNGCNTTYCARMGNGAYAAYGCNMGNAGYTCNCCNCARACNATHTCN ACNGCNCARTCNTCNCARGTNAGYGGNGGNTCNGTNACNGCNGAYMGNYTNATHAAYGCN ATHATHATHCAYTCNATHAAYCARACNTCNCCNGARGAYAARAAYAAYGCNTCNCCNTCN CCNYTNMGNYTNGCNGGNACNCCNACNTCNGAYCARGCNTCNAGYTCNACNAGYGAYCAR MGNCAYATGATHGARTCNAARMGNTAYATGCCNGAY---GGNGGNGGNMGNCCNGAYATG ATGGAYCCNATGCARMGNGARATGATGGAYCARMGNAARMGNCARATHGCNGCNGARCAR MGNCARYTNCARGARATGCAYGGNMGNMGNCARCARGARCAYMGNCARMGNCARCAYCAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATHGARTCNAARCCNTCNACNGCNYTN---AGYTGYAAYGTNTTYMGNTCNACNGTN ATHATHGAYGCNCCNGTNCAYGTNGTNAAYGARACNTTYCCNYTNTGYCCNTTYAAYAAR CAYAARGARTGGGCNCCNGARATHGAYGAYGTNTAYGCNYTNGARGAYYTNGGNCARGGN AARGTNATHTAYCAYGTNAARACNMGNAGYATHGCN---GTNATHTCNCCNMGNAGYTTY GTNGCNGCNGGNGGNCARGAYAGYGARTCNYTNCCNATHYTNMGNTAYGGNGTNAGYGTN GAYTAYCAYAARCCNGTNAARGARGARGGNATGGTNMGNGGNATGTAYGGNCCNTAYGGN GTNMGNYTNGAYCARCAYMGNGGNAAYCCNAAYCARACNAARGCNGARGTNATHYTNCAR ATHGAYTTYAARGGNMGNYTNCCNMGNAARYTNGTNGARAARAGYGTNCCNAGYTCNATG GTNACNTCNTTYAGYCAYTAYATGGARTAYATGAARAARAAYGGNYTNYTNATGTGGMGN TCNCARACNYTNAARMGNGGNMGNCARATHYTNGCNYTNACNCARMGNCAYYTNGCNGCN GARGCNGGN---GGNGCNACNCCNACNCCN---CCNCCNCCNAARCCNAARTCNMGNGGN TTYGGNYTNYTNAARTTYYTNGGNYTNGGNYTNCCNYTNGCNACNGGNGGNGTNGTNGGN TAYGCNTGGTAYGAYAAYGAYTTYMGNAARCARYTNGARGAYAAYGTNCCNTAYGCNAAR GARATGYTNGARAAYGTNYTNCCN------------------------------------ ------------------------------------------------CARGAYGAYATG AARACNCCNAARTCNCARGCNCCNGTNCCNTCNAARGTNGARTCNGGNAARGCNCCNGGN ATGGCNYTNGARAARAARACNGAYGCNAARAARGARGTNYTNTCNYTNGARCARCARYTN MGNAAYAARGARATGGARGAYAARGCNGAYAAYGCNGCNYTNGARGTNGTNATHGAYAAR YTNYTNGARTCNGGNCARAAYTGGGTNTCNGARGCNGCNAARGCNCARYTNGAYGTNGCN AARGCNACNAARAAYCAYAGYACNYTNYTNAARAARGCNATGGAYGARACNTCNAAYATH CAYGAYAARGAYTGYGARTGGGARGCNGTNACNGTNGCNTAYAARGARMGNGARATHACN GTNTCNMGNGCNAAYGARYTNGTNGAYGARGCNMGNMGNAGYATHGARAARYTNAARAAR GTNYTNGAYGARGCNAARGCNAAYAARGTNACNATGAARAAYTCNTCNATHTAYCCNGCN ACNAARAARYTNGCNGAYTTYGCNAAYGARATGTCNAAYGCNGGNGCNCARGTNMGNCAR GCNGAYGCNGAYGCNAARGTNATGYTNAARTAYAARGAYYTNGTNGAYAARGGNMGNAAR CARTTYCARYTNGARYTNGARAGYYTNACNCCNGAYGTNAARGTNGGNGGNAARAGYMGN AARYTNACNGARGARGARYTNAAYGCNYTNATHGCNCAYGCNCAYMGNMGNATHGARCAR YTNCARMGNCARATHGCNGARCAYYTNGCNATGGARMGNAARMGNYTNACNYTNGCNYTN GARGCNCARAARGARGARAAYMGNGGNATHACNAARTCNGCNGTNGTNGAYGARMGNTCN MGNYTNTAYGCNGARTTYGARYTNGARAARCARAARATGGARATHGARTTYGCNGCNTGG ATGGARGCNGAYGTNMGNAARCARYTNAGYMGNCARTCNGCNGCNCAYAGYGAYCAYYTN AARGAYGTNYTNGCNGTNCARGARGCNGARYTNAGYAAYGAYTTYCARMGNAARATGAAY ATGAARYTNYTNGARGARMGNGARAAYTTYCARTCNGARACNGCNAGYTGGATHTCNMGN YTNAARGGNATHGARGCNGCNGTNGAYGCNMGNGCNGCNAGYGARAARYTNGCNCAYACN GCNCARGAYYTNTGGYTNGCNTGYATHGCNYTNAAYTCNACNATHCARTTYGGNAAYGAR ---GTNGARGAYACNCCNATHCCNYTNCARCARCARGTNGARACNATGYTNACNTCNTCN AAYAARCAYCCNTTYGTNGARACNATHGCNAAYACNATHCCNCARGTNGCNYTNGAYMGN GGNATHTAYACNGARAAYAGYYTNMGNGAYMGNTTYGTNAARGTNTCNCARGTNAGYMGN MGNYTNGGNYTNATHCARGARTCNAAYGCNTCNYTNTAYCARTAYYTNGTNTCNTTYYTN CAYTCNTTYTTYACNGTNAGYAGYGTNGCNGCNTAYTCNGARAARGAYYTNGTNTCNYTN GGNGARATGGAYAAYTTYAARYTNGTNGCNAAYGCNCARTAYTGGATGGARAARGGNAAY YTNGAYYTNGCNGTNMGNTTYATGAGYCARYTNACNGGNGARTCNMGNMGNGCNGCNAGY GAYTGGATHACNGARGCNMGNYTNYTNYTNGARACNMGNCARGCNGCNCARACNATHYTN ACNTTYGCNTCNGCNACNGGNYTNGCNTCNACNTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GAYGAYTTY YTNACNYTNGARGCNGCNYTNGAYTAYATHTGYACNMGNGTNGAYGTNGARGARTTYCAR TCN---AAYGGNGAYAAYGTNYTNCCNGGNACNGAYTCNTTYGCNGAYGGNYTNTCNAGY ------------------------------TTYGAYACNACNACNGARATGCARCCNYTN YTNCCNGCNCARGAYATGCARMGNYTNTGYATGGARAAYYTNCARCCNGCNGAYATGGAR AAYGARTGGGGNCARGTNGARGARTAYYTNAAYGTNTCNYTNGTN---GCNCCNACNGTN GCNCCNCAYCARYTNTCNYTNGTNGAYAAYGCNGCNGCNGCNCAYGAYTTYGAYYTNGAY ATGAARCARGAYYTNTCNCCNGTNATGGAYGAYAGYATHTTYACNAGYGCN--------- ---------------------------GAYYTNCCNYTNATHCARGAYGTNTCNYTNCCN TCNTCNGAYATHGARCCNGTNCCNGARYTNGGNGCNGTNACNYTNACN---------AAY ACNAGYATGCCNCCNCARCCN------TGYYTNATGAAYACNTCNYTNGARTGGGARGCN GGNAAYATGACNATHTTYGGNAAYYTNACNGCNYTNCCNGARGAYAAYATHGAYGAYATH GAYYTNGARAAYATGGARGAYYTNTTYAAYACNATG------------ACNGARGCNTCN GAYYTNATHGGNAAYGTNACNCCNCAYACNGAYGTNAGYAAYYTNGTNYTNTCNGGN--- ------------------------------AAYGAYACNATHAAYGTNYTNCCNTCNACN TCNTTYTCNGARGAYYTNGCNGAYGCNTTYGAYGGNYTNGARGGNGCNACNGGNGGNGCN AAYTAYAGYAGY---CCNGAYGGNTAYGAYGCNCCNCARAARAARATHTCNMGNGTNTCN GARTCNTCNTCNGAYTCNGGNTTYGGNGGNAARGGNGCNTTYAGYTCNTCNTCN------ ---TCNTCNGCNTCNTCNTAYGCNGGNAGYCCNGCNGAYTCNACNATGGGNTAYAAYTCN ACNAAYTCNAAYGAYACNGAYCAYGAYCCNCAYGGNACNAARGCNYTNGCNCAYCARGTN GCNCAYAAYCAYACNTAYAAYACNYTNCCNGGNCAYGTNCCNMGNGARGTNAARAARTAY GCNCCNAARCARCAYTCNAARAARGGNCCNCARTGYAARGAYCARAARAARGCNAAYGAR ATGAARYTNCCNTTYAGYGTNGAYGARATHGTNGARTCNCCNGTNGARACNTTYAAYGAY YTNYTNACNAARTAYAGYYTNAGYGARGAYCARYTNACNYTNGTNMGNGAYATHMGNMGN MGNGGNAARAAYAARYTNGCNGCNCARAAYTGYMGNAARMGNAARGTNGGNGTNATHGTN ACNYTNTCNGAYGARATGGTNGAYYTNCARAARGCNMGNGAYMGNYTNGTNGARGARMGN GCNGARATGGARMGNGARACNMGNMGNATGMGNGARAARTTYGGNCAYYTNTAYACNCAY ATHTTYCARTCNYTNMGNGAYGARCAYGGNCARCCNTAYGAYCCNAAYYTNTAYTCNYTN CARCARTCNAGYGAYGGNAAYGTNTTYYTNGTNCCNMGNAAYGTNACNACNACNACNAAR ACNGAYATHAAYGGNAAYGCNAGYGGNAAYAAYGGNMGNAAYGGNACNGGNAAYCAYGAR MGNAAYGAYMGNATHAARAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGTTYAAYAARGTNACNACNYTN GCNMGNTTYGTNCCNMGNGTNMGNAAYGCNMGNTGYATG------GGNCAYGGNGTNCCN GCNCAYTTYAARCCNATHMGNCARGTNTGYCAYGARCAYAARGCNACNATGGAYTTYATG CCNGTNCCNTCNGGNTCNTGGCARAARGCNTAYGAYGCNGCNAAYGCNCARAAYAAYATG YTNYTNYTNGGNAGYYTNGGNGCNGTNGTNGTNACNTTYGCNATHYTNTAYCARACNGGN TGYATHTAYYTNCAYGGNCCNCCNCCNGCNTAYAAY---------------------ATH AARGTNCCNCARMGNYTNCAYAARYTNGTNAAYGARAAYCAYACNYTNYTNGARAARTGY TCNACNGCNAARYTNGTNAARMGNATGCCNAAYACNGAYGTNGCNCAYAAYTTYGTNGAR MGNYTNAAYAARTCN---TAYGARGTNAGYCARGARYTNTGGGCNAARGTNAARGCNYTN ACNAGYGCNCARAGYCAYCAYYTNATGYTNGAYTCNYTNMGNTCNYTNGGNATHGARGAR ATGTCNGARGARATHCCNTTYCARACNGTNTAYMGNACNAARMGNYTNYTNGARTTYATH YTNACNAARTTYGCNCARACNCARGAYGARGCNGAYTAYTTYTCNAARGTNCARTTYMGN CCNTGYAARTCNAGYGGNATGACNYTNACNTCNGAYTCNGAYGARAARGAYGTNATHAAY ACNTTYTTYAARAAYCARGARACNGARACNATGCARATGAGYAAYCARTTYGTNATGGGN ---GCNYTNACNAGYTCNAARACNTGGGCNCAYYTNCARTTYGARAARAAYYTNTAYAAR YTNYTNYTNCAYYTNYTNTGYYTNTCNGARTCNCARTGGTGGAARGTNYTNTGYGARGAY TCNACNAAYGGNAGYACNGTNCARATGATHCAYAGYYTNYTNACNTCNAGYGGNGARTTY ---------------------------YTNYTNYTNTCNYTNMGNACNGCNYTNGARGAR GCNAARCARMGNATHGTNMGNYTNMGNGAYGARAAYGAYGARAARGAYGARATHATHGAR GARGARMGNAGYCAYMGNATHGCNYTNGARNNNAARATGGARAARTAYYTNGTNGAYYTN TAYCARAAYCCNAGYGTNAAYGAYGARYTNCAYCARMGNYTNCCNMGNGCNAARAARAAR GGNYTNYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYTCNGAYGTNGTNGCNGARATHATH AARCARATHYTNGAYTCNGARTCNGCNATHAARCAYGARCARGGNATGGTNYTNYTNGCN AARATHAGYAAYAGYAGYACNYTNGTNCAYTGYATGGTNGCNGARCARYTNAAYAGYAGY AGYTGGMGNTAYMGNGTNATHGCNTGYAARATHYTNCCNACNYTNTTYGGNTCNATHAAY MGNGAYATHACNCARAARYTNTCNGARYTNATGTGGCAYGAYTGGCAYGTNGARGTNMGN AARGCNGCNGCNCARTGYYTNGGNAARACNAGYCAYGGNMGNGAYGTNCAYGAYGAYATH MGNGAYMGNATHYTNAAYGGNACNGARMGNACNAARATGGARGCNATHAAYAARYTNGGN CARYTNGGNATHATGACNGCNAARYTNYTNCCNGCNTTYYTNAAYTGYTTYACNGAYTCN TAYGTNTCNATHMGNTGYGARGTNTGYATHACNTGYGGNAAYYTNCARATHAARGARGAR CARGTNYTNGARMGNYTNGTNCAYYTNGCNTCNTTYGAYCCNATHTGGAARGTNAARGCN YTNGCNATHCARGCNYTNGGNAARATHGGNGARGTNAGYGARGAYATHAARGARTGYYTN YTNTGGGCNATGMGNTAYGARGARMGNCCNGGNGTNMGNGCNGARGCNTGYCAYTCNYTN ACNGCNYTNGAYATHGAYGAYGARGAYGTNATHGARATHYTNCARAAYMGNYTNYTNGTN GARTCNAAYCAYYTNGTNMGNGARGARATGATHGARGCNYTNTCNGTNTTYGGNTAYAGY ACNTCNGARGAYATGGAYACNGTNGCNCARATHAARGCNGARGTNMGNAARYTNTGYACN MGNAAYATHATHGCNTCNCARATHATHGTNAAYGARAAYGAYGTNACNAARMGNGARCAR YTNMGNMGNAARGTNTGYCARACNGARAARGAYATHGARACNYTNAAYGARMGNAARGAR ATHATHYTNMGNMGNATHMGNTCNCARGCNMGNAGYAGYMGNGCNAGYAAYAARGAYAGY YTNAGYTCNTCNCCNCCNCCNMGNACNTCNACNCCNYTNYTNCCNACNGTN------AAR CAYAGYAGYACNACNACNCCNGARCCNGTNAGYMGNGARGGNACNGTNTTYACNCCNACN GCNGAYAARGARYTNGARGCNATHYTNAAYCARGAYGARGAYYTNGARAGYATHACNGAR TCNACNAGYGGNAARTCNMGNCCNGTNACNGAYGGNTCN---------ATGGTNGARYTN GGNACNGCNACNCCNGGNGAYAARGAYGAR---------AARCARGTNCCNTCNMGNATH ACNATHACNAARGCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GTNCCNCCNYTNGCNATHTCNATGGAYACNGAYCAYTTYAARTGGYTNCARGARCAR GCNTCNAARGCNCARGTNMGNGCNMGNCAYAGYTCNAARATH---AARCCNGAYYTNMGN CCNGAYGTNACNATGGARGGNATGGARGARGGNGAYGARGARAGYAGYCAYTCNATHMGN YTNGARACNYTNAARAARGARGARGARCARAARTAYYTNGCNTTYGCNAARGARGTNACN GAYGAYGTNYTNACNMGNGGNATHTCNACNGAYAARGTNYTNCAYAARGTNTTYGARAAY CAYATHGARMGNMGNAARGGNGAYYTNGAYGARACNMGNATGMGNGCNATGATHAARGAY YTNAARAARGAYYTNGGNYTNMGNGARACNTCNGTNGARMGNAARGARAGYCAYACNGTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TTYMGNATH MGNGCNGARYTNGCNGARTTYGARAARATGCCNGARMGNGTNAAYAAYACNACNGARGGN YTNAARCARGAYATHTTYGGNCAYCCNCARMGNTGYCAYTGYYTNGTNGCNGARGAYACN AARAAYACNGARGCNGGNGTNGTNGGNTAYGCNYTNTAYTTYTTYCCNTAYTCNACNTGG GAYMGNACNTTYATGCAYYTNGARGAYYTNTAYGTNAARCCNGAYTTYMGNGGNAARGGN ATHGGNAARAARATGTAYCARGCNTGYGCNCARATHGCNATHGAYYTNAAYTGYCARMGN YTNCARYTNGAYGTNYTNGGNTGGAAYAARCCNGCNAARGAYTTYTAYGARMGNATHGGN AAYGARGAYAAYACNGARGTNGARGGNTGGCAYAARATGMGNATGAARMGNGARCARATG GARAARTTYGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARGGNAGYTCNTCNATGAARATHTAYGARGAYAAYCAYAAY ACNYTNGARATHGGNYTNGTNMGNTGYTCNMGNTCNGTNCARACNGAYGARAGYYTNYTN GARAGYTAYATHCARAAYAARCARYTNCARAAYGTNAAYGTNTCNACNGAYAGYGGNCAY YTNTCNGGNTGYTTYGAYCARGARGCNTAYGAYYTNATGGTNAAYGARCAYGTNCCNGAR AAYTAYTGGAARGAYYTNGCNGARCARMGNMGNCARGCNYTNAAYGAYACNYTNGARGAR AAYGARAARYTNTCNGTNGARGTNGARCAYYTNAARGARGARAAYMGNMGNYTNTCNGAY ATHGCNTCNAARGCNGARTAYYTNGARAAYYTNYTNCARGAYGCNYTNTCNGAYGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ACNATHMGNYTNYTNCARCAYATHAARAARGTNMGN GCNGCNATHGARTCNYTNCARCAYGAYATHAARTCNGARTCNGARCCNGCNAGYATHAAY GTNGGNCCNATHCCNGARTAYGAYGGNCCNCARATHAARGAYMGNTCNCAYCARAARTAY TTYACNGARGARGARTAYGARAGYGAYTTYGTNAARGGNGTNCCNAARCCNCARCCNCAR ATHGAYGARGCNACNTGYMGNAAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TTYAAYTAYMGNYTNTCNTGGYTNGGNTTYGTNAARGGN CCNACNGAYGARATHAARGGNAAYATGGGNYTNTGGGAYCARYTNGARGCNYTNAARTGG GTNAAYAARAAYATHCAYTCNTTYGGNGGNGAYCCNAAYGAYGTNACNYTNGCNGGNCAR TCNATGGGNGGNGARAGYGTNTCNGCNTTYAGYGTNATGAARCARGCNAARTAYYTNTTY ACNAARGGNATHYTNATGAGYGGNTCNATGTTYTCNAAYAARTCNACNGTNACNTCNTCN GAYCARYTNYTNGAYCARYTNATHGAYAARACNGGNGARGGNYTNGTNAAR--------- ---------------YTNMGNAAYYTNCCNCAYGARAARTTYGTNYTNCCNYTNCARAAY GARATHACNAAYCARTTYACNACNATHGAYGGNGARYTNTTYCCNGCNTCNTTY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TAYATHYTNATGGGNATHGTNTAYATGMGN GGNTGYTGGCAYGCNTTYGTNCCNATHTTYCARGGNTAYGARCCNGGNTAYCAYTGYMGN CCNGCNCCNGGNATHCCNYTNAAYGARTCNGTNCCNMGNCAYAAYGAYAGYGGNGGNYTN GARTAYGAYCARTGYACNCARTAYGTNAAYTTYTCNYTNGGNAAYCARACNGARGAYTGY ACNMGNGGNTGGGTNTAYTAYTTY---GAYAGYCAYACNTCNTCNATHGTNTCNGARTAY ACNYTNACNTGYGAYMGNTCNTAYYTNAAYAAYYTNGCNACNACNYTNTAYATGGTNGGN GCNACNTGYGGNGTNATHTTYYTNACNCCNYTNTCNGARMGNGTNGGNGGNAARCCNGTN ATGYTNGTNTGYYTNTGGYTNCARGCNGTNATHGGNACNGTNYTNCCNTGGGCNGGNAGY ATHGTNTTYTAYYTNGTNYTNAARTTYTTYATHGGNGTNTTYAAYATGACNATHGCNYTN TGYGTNGCNGTNYTNATGCAYGARACNTTYGAYTCNACNCAYMGNGARATHCCNTCNATH GGNGTNCARTTYTTYTGGGCNTTYGGNATHATGACNYTNGCNYTNTTYGGNTAYYTNYTN CCNGAYTGGAARCAYYTNCARYTNGTNATHACNYTNCCNGTNCCNATHYTNAGYATHGCN TTYATHTGGYTNATHCCNCARTCNYTNCCNTGGYTNYTNTCNAARGGNAARYTNAARGAR GCNGCNMGNGTNATHAAYMGNTTYATHAGYATHAAYAAYYTNCCNGCNATHCCNAAYYTN GAYAAYGTNYTNTTYAGYTTYAARAAYAAYGTNAARGAYAAYATHTCNGAYTCNAGYYTN AAYAGYCAYGGNGAYGAYCAYGTNTCNTCNAAYCARGGNTAYGAYGARGGNAAYTCNTCN TCNAARGTNTAYACNGTNYTNGAYATHTTYAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATGCAYCCNTAYTAYTAYGTNCARTAYGTNCCNATHCCNYTNAARCARGAYYTNGAR ATGAARGTNAAYTGGGCNGCNTCNCCNAGYACNGCNCCNAARCARGAYACNAGYAARCAY TTYCAYGTNTTYGTNGGNGAYYTNAGYTCNGAYATHGARCARCAYCARYTNMGNGAYGCN TTYTCNATGTAYGGNGARATHTCNGAYTGYAARATHATHMGNGAYCCNGCNACNATGAAR TCNAARGGNTAYGGNTTYGTNTCNTTYGTNAAYAARTCNGARGCNGARACNGCNATHAGY GGNATGAAYAAYCARTGGYTNGGNACNMGNCCNATHMGNACNAAYTGGGCNACNMGNAAR CCNYTNGCNCCNGTNGTNAARGARAAYGCNAARCCNYTNYTNTAYGARGARGTNTTYGGN CARTCNAGYCCNACNAAYTGYACNGTNTAYTGYGGNGGNGTNACNAAYGGNYTNACNGAR GARYTNATGMGNAARACNTTYTCNCARTAYGGNACNATHCARGARGTNMGNGTNTTYAAR GAYAARGGNTAYGCNTTYATHMGNTTYAGYACNAARGARGCNGCNACNCARGCNATHTGY GCNATHCAYGGNACNACNATHAAYGAYCARCCNGTNAARTGYTCNTGGGGNAARGARTCN AAYGARTCNAGYCARACNAAYCARCARTCNAAYAGYCCNCCNGTNGTNATGGTNCCNTCN CARCARCARCARCCNATHGCNGCNACNCCNGCNGCNGCNCCNTAYGGN---CARTTYTAY AAYATGAAYTAYTAYCAYGGNGCNCCNTAYGCNGCNGGNACNCCNACNTAYCARAGYGCN GTNCCNACNCARGGNCARTTYATHCCNACNGCN---GGNCARTGGCCNGGNGGNTAYTCN AAYTAYCARGCNTAYGGNAGYATGAAYGTNCCNGTNGGNGGNTAYGCNGGNYTNCARATG CARCCNGGNGCNCARCARCARCARTTYAGYGGNCARGGNCARGGNATGGTNGGNTAYCCN ATGCARCARGGNATGGCNMGNTCNAAYGTNMGNTAYGARGTNYTNCCNTCNGARGARCAR AAYGTNGCNGCNGARCCNGTNGARGTNGCNATGGTNGTNCCNCCNCCNAGYTAYACNGAR AAYGCNGTNATGGARCARGAYGGNGAYAAYCCNGCNTTYGGNCCNTCNAARYTNCCNAAY TAYGTNGAYGCNACNACNYTNCCNACNTAYGARGARGCNGARMGNAGYAARGCNGARGAR ------TCNACNTCNCCNAGYAAYCARGAYTGYGARACNGGNMGNATGGCNTCNATHAAY GGNGTNAAYGARGCNACNATHGGNACNGAYGGNATGTTYATHTGYACNTTYTTYATHTCN TTYYTNTTYAAYTGGYTNGGNTTYYTNYTNTCNYTNTGYYTNTCNAAYACNATHGCNGGN MGNTGYGGNGCNYTNTCNGGNYTNGGNYTNTCNATHGTNAARTGGGTNGTNATHGCNAAR MGNAAYAAYTGGGGNACNGAYTTYGCNGAYGGNGAYTCNTGGYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYGARGAYMGNYTNTCN AAYTTYYTNGAYACNCCNMGNCARGAYGAYCAYTCNATGGTNCCNATGTCNCCNGCNAGY AARYTNCAYCAYYTNYTNYTNGARTCNCARGARATGATHMGNTCNYTNGARAAR---TCN CARGARATGGARATHGAYYTNATHAAYMGNGAYCCNAAYAAYYTNAAYGAYCAYGTNMGN GTNTGYTTYGAYGARGTNATHGGNGARCCNGAYGGNGCNCAYTCNATHAAYTGYGTNTGG ACNAAYAGYTAYMGNTGYTTYAAYTGYTGGAARAGYTGYTGYTAYAAYYTNYTNACNATH TTYTGYGGNATHCCNYTNGCNATGTGYTGGGGNTGYGARTTYGCNGGNATHACNTTYTAY CAYGTNTGGAAYGTNACNCCNTGYATGMGNGCNTAYATGATHCARTGYGGNTGYATGCAR AARTTYTAYGGNGCNTGYYTNCARTGYTGYATGCARCCNTGYTTYGARTCNATGGGNTTY YTNYTNAAYAAYATHAARGTNACNAAYGTNAGY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNTCNGAYTTYTCNGTNTAYAARGAYTGGCARCCNMGNACNCAYTCNYTNACN MGNTAYAAR---AGYTGGGGNAGYGAYYTNGAYTCNACNCAYAAYACNACNTTYGGNACN AARAAYAGYTAYACNGAYTTYTCNMGNYTNAAYCARTCNGTNGGNAAYCCNMGNAARGAR YTNACNGCNGTNCCNAGY---------GTNGTNGTNCCNGAYACNAARGARYTNTGYMGN MGNYTNGARGAYAARATHAAYAGYYTNACNMGNATGGGNGGNAAYYTNCARAARGARAAY MGNGARATGGCNAAYYTNATHGAYMGNCARGGNGARAARYTNGAYACNGTNAARCARATH GARAARAARGCNMGNGARACNAAR------------------------------------ ------------------------------------------------------------ GGNTCNYTNGTNMGNCARYTNATHMGNGGNTCNAARACNAAYGARTTYYTNGCNCARGCN GCNAARAAYTTYGCNTCNCARGARAGYTAYATHCARAAYTCN------------ACNGAR ACNATGAARAARATGGAYGTNGTNMGNTCNCARYTNGARTTYCARCARTCNGCNATHTCN MGNAGYYTNCARCAYYTNGAYGARGTNCARGAYCARYTNTCNACNYTNCARCAY------ ------------------------------------------CCNTCNGARAARGCNTTY AAYTGGTAYYTNGARAAYATGCAYAARTCNGGNGAYTGYGTNGTNYTNGCNCAYTGYTCN CARTTYCARYTNCAYATHGGNYTNCCNGGNGTNGTNGTNAAYGTNGAYAAYGTNAGYAAR CARGTNGARGARTCNAARGCNATHTCNGAYAGYATHATGGCNAARGCNACNGCNGTNYTN MGNGCNAARGGNATHTCNGCNTAYCCNGTNGTNACNAGYTAYTCNAARGCNCAYGARGGN YTNYTNCAYACNGCNCARGAYGARAARGTNGAYCAYATHATHATHGGNAGYMGNGAYYTN GGNGCNGTNAARMGNGCNTTYGTNGGNAGYGTNAGYACNGARGTNGTNMGNCAYGCNAAR GTNCCNGTNACNGTNGTNAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYAARTAYGTNATGAGYGGN TCNGAYTGYGGNMGNATHTTYATHTGGGARMGNGARACNGGNMGNYTNGCNATGTAYYTN GARGCNGAYAARCAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---TTYGARGGNTAYAARYTNATHTCNGTNACNGCNAARTCNAARAARGARGTNCARTTY YTNCARGCNYTNCARAARGGNTAYAARGARYTNGAYTTYTGGAAYGGNCCNTCNCARCAY AARACNAAYATHYTNATGYTNCCNCCNGAYYTNYTNACNCCNATHGARGARGCNATGACN AARGARGGNATGGCNTGGAARGARYTNGGNGCNGAYGTNGCNAARATHATHGARGAYGGN ATGMGNTCNACNCCNTCNGGNCAYMGNCAYATHMGNTCNGCNGAYGCNTCNGAYATHATH GAYCAYACNAAYTAYCAYAGYTAYCARCARATHATHGAYTAYATGGARATGYTNGARCAR AARTAYCCNGAYATHGTNAAYATHTCNTAYYTNAARTAYCCNTCNCAYGARGGNMGNMGN GTNACNGTNATHAARYTNCAYAGYTCNAARYTNTCNTCNAGYAARTCNTCNATHGTNATH GARGCNGGNATHCAYGCNMGNGARTGGATHGCNCCNGCNGCNACNATHTAYAGYATHGAR AARYTNATHCARMGNTAYCCNGCNGGNAAYAAYAAYGCNAARYTNATGYTNGAYACNTTY GAYYTNTAYATHGTNCCNGTNACNAAYCCNGAYGGNTAYGARTAYACNMGNAARGGNCAR AARACNMGNYTNTGGMGNAARAAYMGNMGNYTNATGACNTGGAAYTGYCARGGNGTNGAY YTNAAYMGNAAYTTYGAYGTNTAYTTYGGNACNACNGGNGTNTCNAARGARTGYGAYTCN GAYATHTAYCCNGGNATGCAYGCNTTYTCNGARCCNGARTCNGCNAAYATHMGNGARYTN GTNMGNTCNYTNAAYGARTCNYTNGTNGTNTAYYTNTCNATHCAYGCNTAYTCNCARTTY YTNATHGTNCCNTGGGCNTTYTCNAAYGCNGGNYTNACNTCNCAYAAYAAYGARGARACN ACNGARYTNGGNACNAARATGGTNGAYTCNATHAARGAYACNAAYGGNAARGTNTAYAAR GTNGGNACNYTNTGGGAYYTNYTNGARTAYGCNGCNAGYGGNTCNGCNGCNGAYTGGGCN YTNCARGARAAYCCNGAYATHTAYGCNATGTCNTTYGARYTNMGNCCNAAYGAYMGNGAY GARMGNGGNTTYAAYYTNCCNCCNAAYGARATHATHCCNACNGGNCARGARYTNYTNGCN AGYYTNGARACNATGGCN------------------------YTNTGYMGNTCNTGGYTN GTNCCNACNCCNCARCCNCARAARGARMGNGTNTTYTTYATHGCNTTYYTNACNTGYGTN TAYGTNTGYATGGTNATHGGNTGYGCNACNGCNGCNMGNGTNGGNTAYYTNGTNAGYAAR MGNGTNAARCARGARATGMGNMGNACNACNMGNYTNTAYCAYCARGARGARGAYGTNCCN GAYATHMGNGARYTNTCNGTNYTNGAYGAYYTNAARMGNCAYCAYAGYYTNTCNTGYYTN GCNGTNTGYGGNATHYTNACNTGGYTNCCNATHGCNATHATGYTNACNYTNCARAARTCN GGNGTNCAYATHAGYGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNMGNCARATGTGYTAYGCNTGYCARTAYGTNYTNAAYGGNCCNGAYATH GARTGYGTNACNGCNCCNYTNAAYTGGACNGGNGGNATHATHMGNATGMGNTGYCCNACN MGNTGYACNATHATGGCNGARTAYGAYGCNACNACNGGNAARCCNACNTTYTTYCAYMGN GGNTGYGGNGTNGGNTCNAGYGCNCARGARGARGGNTGYAARGAYGTNGGNGCNMGNCAY AAYTGYTTYTTYTCNTGYGGNGAYGGNCAYGAYTAYTGYAAYAGYCARGCNYTNGTNMGN TCNCCNCAYAARGGNCCNGGNGGNGGNTGYGGNGCNYTNMGNAAYGGNAGYCAYGAYYTN ACNGARGCNTGYAARATGGCNGCNAAYGGNATHGGNAARGAYTGGAARAAYGTNTAYTCN MGNYTNCCNTTYGAYCCNCCNMGNGAYCCNACNMGNYTNCARMGNGAYATHTCNGTNYTN GAYCAYATHGCNTAYMGNAGYGAYATHCCNCCNGARAARCARGCNYTNAARAGYYTNGAR MGNTGGMGNGCNYTNCAYMGNAARGGNGAYGTNAAYGARYTNATHCARGTNYTNMGNGAY GTNAARAARAARMGNYTNGCNGCNGARYTNMGNAAYMGNTTYATH--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------YTNACNYTNGCNGTN GGNGGNGARGGNATGGTNTAYGGNGGNTAYATGGTNAAYCAYGTNGAYTTYGCNCCNGGN TAYGCNGGNGTNATGTTYGGNATHACNAAYTTYGTNTCNACNATHCCNGGNATHATHGCN CCNATHGTNGTNGGNGCNYTNACNCCNAAYAARACNCARGARGARTGGMGNAAYGTNTTY TAYGTNTGYGGNGTNTTYACNYTNATHGGNGCNGTNGTNTTYGGNGGNTTYGCNAARGGN GARACNGARCCNTGGGCN------------------------------------------ ------------------------------------------------YTNTCNGARGAY CARCARGARAAYGARAARMGNGTNGAYGTNGTNAARCAYGCNTTYCARAAYATHTCNAAR AARTCNGGNGCNGTNYTNCARGCNCARGGNAGYGAYTTYGAYAARMGNYTNAARAARYTN CCNGARACNGGNYTNGGNCAYGCNTTYYTNGARTCNGCNCARGGNYTNACNACNGAYTCN YTNYTNGGNTTYACNTGYCAYGTNTGYGGNGARTGYCARGGNAAYYTNGCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYMGNGAYAARTTYGAYGGNTAYGTN TTYYTNGAYGARAARGGNGGNGARTAYCCNGCNGTNGTNGARTTYGCNCCNTTYCAYAAR GTNACNAARAARAARCARMGNAARYTNGAYTCNAARTGYGGNACNYTNGARCARGAYTCN GAYTAYAARMGNTTYYTNGARTCNYTNGCNAAYCCNCCNGARACNCCNTCNGTNTCNYTN GAYGCNATHGTNGARGARGTNGARGCNAARGARYTNMGNYTNGCNAARYTNGGNTCNACN AARACNAAYACNCCNYTNYTNGARTAYYTNAARMGNMGNAARGARGARAARMGNATGAAY ATGGTNAARATGMGNGAYGARMGNMGNMGNGGN------MGNGAYMGNGAYTAYGAYMGN MGNMGNTCNGCNAARGAYGARGGNGGN---------------------------GGNAGY GGNMGNAARGAYMGNGAYMGNCARATGGAYMGNGAYMGNMGNMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYATHATHGARATHYTNCCNGARTCNGGNCCNTAYYTN GTNTAYTCNATHACNGGNTGGTCNGAYTCNGTNATGAGYAARTTYGTNAGYGGNGGNYTN GAYCAYYTNCARATHCCNYTNGTNGARAARACNATHGARGGNGTNMGNAAYAAYYTNCCN CCNTCNGCNGARGGNAARAGYTTYAARAAYAARTAYGGNYTNGAYGTNTCNATHAGYTTY AGYAAYGGNTAYACNGARACNYTNAGYYTNGTNATHCCNGGNGTNYTNCCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARCARATHMGNGGNGGNGGNGARYTNTTYAARTAYCCNTGGACNGCNTAY TCNAARGTNCARCARTTYCCNTTYAARTTYTAYTGGACNCAYTCNMGNGTNTTYMGNTAY TTYTTYTTYTCNTCNGCNYTNGTNTTYCCNYTNATGGTNAARATGACNAARGCN---GAY GCNAARATHTTYCAYCAYGCNCARYTNGCNCARGCNCAYYTNCARYTNGGNGGNGTNCCN GTNTTYYTNCCNCCNCAYCCNGCNGCNGAYCARGCNGCNATGMGNCCNCARYTNCCNACN YTNGTNCCNGTNAGYGGNACNGCNGCNATGACNGAYGARCARCCNMGNTTYYTNCAYCAR CAYYTNGGNATGCCNATG------CCNMGNCCNGCNCARCCNTTYATHYTNGCNGCNCCN MGNYTNCCNCCNCCNACNGTNGTNGCNTCNAGYCARCCNAGYYTNAAYGGN---GCNCCN CCNCCNYTNGTNTCNCCNCCNCAYGARGCNGCNGGNYTNGTNTAYAAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------- >stephanieae YTNTTYATHGCNCCNYTNYTNYTNGGNGTNGCNTTYGCNAGYTAYGAYCCNTAYACNGAY YTNGCNCARYTNTAYMGNATGCARYTNYTNGCNGAYGCNTTYGGNGAYTAYATHCCNGAR AAYYTNCCNYTNGARAAYACNAAYGAYMGN------------TCNTAYTGGCCNGARTTY ---------------GCNGCNTCNYTNGARCCNTCNAARTCNTCNAAYGAYATGTAYGGN TCNCARATGTAYAGYGGNGCNCAYATHMGNGAYCARGARCAYATHGARCAYAGYGCNYTN CAYGGNTAYCARTCNGTNGCNGGNGGNACNGCNGARGGNCCNGCNAAYAAYAARATGACN AARAGYGAYAARCCNYTNCCNGCNTAYTGYAAYCCNCCNAAYCCNTGYCCNGTNGGNAAR ACNGCNAARGAYAAYTGYGTNGARAAYTTYGARAAYTCNGCNGARAAYAAYAAYAARYTN YTNAGYGARCARGAYTGYCCNTGYGAYACNGARCAYATGTTYAGYTGYCCNGCNGGNCAR GARACNGTNTCNTCNAARGGNAAYTCNGGNTAYCARCARACNYTNAAYAARGTNATGGAY CARATHTCNAARATHAAR------GCNTCNAGYCARGARAAYAGYGCNYTNYTNAAYCCN ACNMGNAARMGNATHACNYTNGTNGCNAARAARTCNCCNCAYATHATHCAYAARMGNGCN GARAAYGCN------CCNAAYCCNTAYYTNCARGGNAARCCNATGGAYATHGCNGCNAAR AARGAYATGCARTCNTCNCARGAYTTYTAYTAYCARACNGCNATHMGNCCNMGNTCNATH TTYACNCARATHACNAGYTGGATHACNGCNTTYATHGCNATHGARMGNTTYATHAGYGTN GTNTTYCCNTTYAARGTNAARCARATHGTNACNCCNAARMGNTGYTGYTTYATHGTNGCN AGYATHTTYYTNGTNACNACNGCNYTNTAYTAYCCNCARTAYATHAAYAARAARYTNATG AARATHMGNTTYTTYTTYATGGTNCARTAYMGNTAYATHAGYACNMGNYTNATHATHATH GTNTTYYTNTGYAAYGTNGTNATHATHTGGAARGTNGTNATHGCNACNAARTTYMGNAAR TCNAARGCNACNTCNGAYTCNAARGARGAYAAYAARGGNGGNAARGAYCARAARYTNGTN MGNATGATGGTNGTNATHTGYGTNGTNTTYYTNGTNTGYGTNGTNCCNTAYACNTTYYTN GCNTTYGTNYTNCARGTNAARTCNCAYTTYTAYATHGAYGAR------------------ ---TGYGTNTTYGCNACNAGYATGTTYTTYGARACNYTNAGYGCNGCNAGYAAYATHTTY ATHTAYTTYACNYTNAGYACNMGNTAYMGNAARGARTTYAGYAARTGYTTY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARGARCCNAAYGARAAYGTNGCNGAYYTNTAYGARGCNTAY YTNMGNGGNCARGCNTTYCCNAGYCARTAYAAYAAYGARCAYAARAARTAYYTNGCNGCN AARCARMGNATGAARATGAAYCARAARAARAARGTNGCNAARYTNYTNCARGARTGGGAR AARGCNMGNCARCAYGTNAAYGARGTNMGNAARACNGAYCCNAARACNGCNGAYMGNATG AAYGAYGARATHGCNCARMGNTTYAARCAYYTNTAYGCNTCNTTYAARCARGARGAYGCN TCNGARAARATGCARYTNGCNGCNYTNCAYCARCARCAYATHCARGCNYTNYTNAAYGCN AARAARMGNGARGCNATGGAYMGNTAYATGAAYGCNYTNGARAGYGARAAYATHCCNATG GTNAARAARTAYYTNCAYAAYTAYATHAARGCNGARGARAARGAYMGNATGCAYACNGTN AAYCAYTTYGARCAYYTNMGNAAYTCNAAYCCNAARGARGCNYTNMGNGTNCAYCCNCAY ATHATHACNCAYYTNAARYTNTCNGARATGMGNATHGAYCARGCNYTNGARATGYTNACN CAYTAYCCNTCNGTNGARATGGCNGTNMGNCCNGARATHGARGARTTYYTNAARAGYTTY AAYGARATHGCNACNAAYATHAARAAYYTNGTNYTNCCNGTNCCNGARGTNGAYAGYGAR GARGARACNAGYTCNAGYAGYGAYTCNGAYAGYTAYACNGCNTCNAAYGAYGCNAGYTAY GAYAARGAYAGYAARTAYGAYACNAGYAGYGARGARGARTCNGAYAARGARCAYGARGAR GARGARCARGARCCNGAYAGYTAYGGNGCNTCNTCNACNGTNATHGAY------------ ---------------------------GAYGARGTNCARGARAAYGARCAYAGYTAYGAR GARAAYCAYCAYTTYGCNGCNAAYGCNCARTCNGAYATGCARAGYGTNAAYCAYGGNYTN MGNTCNGCNAGYAGYTCNGGNACNCARATGGGNAGY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARGAYAARYTNTAYMGNCARATHACNGTNGARGTNAARGGNCAYGAYCCNGCNGTN YTNAAYAGYTAYCARAARTTYACNACNTCNGCNGCNGARCARYTNGGNGTNAARATHGCN AARATHTCNGARCCNCCNAARGTNATHACNMGNAARAGYYTNYTNAARTCNGTNTTYATH TTYAARAARCAYCARCAYCARTAYGARACNMGNACNYTNTTYMGNGTNTTYGARTTYAAR CAYYTNACNGARTCNACNGCNYTNACNTTYYTNGARTAYATHCARMGNAAYYTNCCNGAR GGNATGGCNATGAARGTNACNAARCAYGARYTNYTNCCNATHCCNGAYCAYYTNAARCCN CCNAARCARCCNCARTCNTCNTCNTCNTCNCCNTCNGAYTAYTTYAAYGTNATGYTNGGN ACNCARYTNYTNTAYAARTTYGARMGNCCNCARTAYGGNGARATHYTNGCNGARCAYAAR GAYAARCCNATGTCNAGYATHTAYGGNGCNACNCAYYTNYTNMGNYTNTTYGTNMGNYTN GGNGCNATGYTNGCNTTYACNTCNYTNGAYGARAARACNGTNCAYATHYTNYTNAAYCAY GTNCAYGAYTTYYTNAARTAYATGTCNAARAAYGGNGCNACNYTNTTYAARACNTCNAGY TAYGARATHGCNACNCCNGAYTAYCAYMGNAARGCNATH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TAYATHGAYGTNACN TTYTAYATHYTNATHMGNMGNMGNGTNYTNTAYTAYTTYYTNAAYGTNATHATHCCNTGY ATGYTNYTNTCNACNYTNTCNYTNACNGGNTTYYTNYTNCCNCCNGAYTCNGGNGARAAR GTNACNYTNGGNYTNACNGTNYTNYTNGCNTTYTCNGTNTTYATGYTNYTNGTNGCNGAR AAYATGCCNCCNACNTCN---------------TCNAARCARMGNTGGATHCCNYTNGAR TCNAAYCCNACNACNYTNAAYAARTAYGTNCAYGGNYTNGGNATGGAYAARGCNTGGAAY TTYGTNGAYGTNTTYGGNYTNGAYCCNGARYTNYTNGCNATGGTNCCNMGNCCNGTNGCN GCNGTNGTNYTNYTNTTYCCNGAYGCNAARTCN------------CARAGYGCNATHGGN GARTAYATGAARGAYGCNCCNGARGAYYTNTAYTAYACNAARCARACNATHGGNAAYGCN TGYGGNACNGTNGCNYTNGTNCAYGCNYTNGCNAAYAAYCARGAYAARATHTCNTTYGCN GAYGAYAARCCNTTYTCNAAYTTYYTNAARGCNACNAARTCNATGAAYCCNGAYGAYAAR GCNAARCAYYTNGARAGYGAYATGCARATGGGNGCNGCNCAYGARGAYTGYGCNCARGAR GGNGAYACNGCNGTNCCNGCNGCNTCNGAYAARGTNAARTGYCAYTTYATHGCNYTNGTN CAYTTYAAYGGNACNYTNGTNGARYTNGAYGGNMGNAARGARGGNCCNGTNAGYCAYGGN GCNACNTCNGCNGAYAAYYTNYTNGARGAYGCNGCNGCNGTNGTNAARAARTTYATHGAR AAYAGYCCNTAYGAYAARGCNMGNATGCARATGYTNCARAARGAYMGNAGYACNCAYATH GGNTAYAARYTNACNYTNTCNTCNGAYGARAARATHGTNTCNGAYGTNATGGTNAARGAR AARGCNAARYTNATHGARGARAGYMGNCARGGNCAYAARGARTAYTTYCCNTCNYTNAGY TTYTAYMGNTCNAARCCNYTNATHGARAAYACNCARGTNTAYAARYTNATHAARAARATG CCNAARGGNGCNGCNYTNCAYYTNCAYGAYCARGCNATHGCNAGYYTNGAYTGGYTNGTN AARAAYGTNACNTAYMGNGAYCAYYTNTAYATGTGYGTNAAYAARACNACNAAYACNYTN CARTTYAARTTYCAYAARGARGCNCCNGAYTCNAAYTGYAAYTGGTGYTCNGTNAARGAR AARMGNAGYYTNGCNACNAGYGCNTTYGARTTYGAYGARAGYATHATGMGNAAYATHAGY YTNYTNGCNACNGAYCCNYTNGTNACNTTYCCNGAYGTNAAYAGYGTNTGGGARAARTTY ATGCARTAYTTYGGNCARGTNTTYAAYATHATHTTYTAYGCNCCNGTNTTYMGNGAYTAY TTYMGNCARGCNYTNATHGARTTYTAYGAYGAYAAYGTNCARTAYATHGARYTNMGNTCN YTNTTYGAYGGNGTNTAYGAYYTNGAYGGNACNACNCAYGGNMGNCARAARGCNTTYGAY ATHTAYCARGARGTNACNAARGARTTYACNAARAGYCAYCCNGAYTTYATHGGNGCNAAR TTYATHATGTCNGGNYTNMGNAAYAGYAARGARAGYGAYATHYTNAAYGARATHAARGAR ACNATGGCNATGMGNGARTCNGCNCCNGAYTTYATGYTNGGNTAYGAYYTNGTNGGNCAR GARGAYCCNTAYAAYTCNYTNYTNCAYTAYMGNAAYGARYTNYTNTAYCCNAGYCARACN GAYCCNGCNAAYCCNYTNCCNTAYTTYTTYCAYGCNGGNGARACNAAYTGGCARGGNACN GARACNGAYTAYAAYYTNATHGAYGCNGTNYTNYTNAAYACNACNMGNATHGGNCAYGGN TAYGCNYTNATHAARCAYCCNACNYTNGTNGARACNATHAARAAYAARGGNATHGCNGTN GARGTNAAYCCNATHTCNAAYCARYTNYTNGGNYTNGTNAARGAYYTNMGNAAYCAYGCN GCNGTNCCNYTNTTYGCNAAYGAYATHCCNGTNGTNATHAGYTCNGAYGAYCCNGGNACN TGGGARGCNAGYCCNYTNTCNCAYGAYTTYTAYYTNGCNTTYATGAAYATGTGYGGNGAR GAYGCNGAYYTNMGNGCNYTNAARCARYTNGCNTAYAAYTCNATHAARTAYAGYGCNATG AAYGARAAYGARAARGCNAAYGCNATGACNYTNTGGGARTCNAARTGGAARGAYTTYATH CARCARGCNGTN---TCNAGYAAYCAYGTNTCNCARCARCAYAAYGARGTNGCNCCNACN MGNGTNAARMGNGGNAAYTAYAAYATGATGMGNYTNACNMGNGGNYTNAAYATGYTNMGN YTNGGNAARMGNGGN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GCNACNGGNYTNCCNATHGAYCAYGAYATHYTNTCNYTNGARGAYGGN GAYTAYTTYMGNYTNYTNGGNAAYGGNTAYTAYTTYATHACNGCNGAYGCNCCNGGNTTY CAYCARAARGGNCAYTGYYTNMGNGTNMGNAAYAAYYTNCARATHGGNGARACNAARGAY GARYTNCAYCCNGCNCCNATHGTNAAYTTYGTNYTNACNCCNGAYAAYGARGARAARGAR GTNATGAGYGAYGARGAYACNGCNTGYCARGARYTNGTNGAYGARATHGARGARCARACN GARATHGAYGAYMGNGAYYTNYTNGTNTCNGTNYTNTCNTAYYTNGARCCNGGNTAYAAR TGGTCNTAYTAYTCNCARCAYAARACNGTNYTNGARYTNTAYTAYTAYYTNGTNGARGCN YTNCARMGNYTNGARGCNTCNGAYATGMGNGCNGTNYTNAARAARYTNCCNMGNGCNGTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNCCNAARMGNTCNGCNGAYGAYATHYTNCARGAYACNCARGGNATGGTN YTNGAYAARMGNCCNAARTAYATGGAYACNMGNMGNGAYYTNGAYATHTTYAARGAYYTN GTNYTNATGAGYGTNCARGARYTNGTNGAYGARGGNMGNYTNGARTCNTCNATHYTNCCN GARGARGARMGNGAR------ACNAGYAARCCNGTNGARAARMGNMGNTAYATGGGNYTN TGYATGCAYMGNCARGCNAAYCARTAYATHCCNTTYCCNTGYYTNMGNACNGGNMGN--- ATGAARGCNGTNTTYTGYYTNYTNYTNATHGGNTGYGCNGTNYTNGCNGAYAAYTAYYTN TGYCCNCCNAARAAYGGNGAYAARTTYGARTGYTTYGARTCNGAYGCNGTNTAYMGNGCN TGYYTNACNGAYGGNMGNMGNGGNGAYGCNTAYGTNGTNTGYTCNAARTGYAARMGNAAR TGGGARTTYTGYGTNACNCAYGGNAARTTYCARGARTCNAARAAYCCNGARMGNGAYTGY GGNGCNGAYTAYAARACNACNCCNTGYGTNCCNGARAAYTCN------------------ ---------------------------------GCNTAYCCNTTYTAYGCNGAYYTNATH CCNAAYGGNTCNAAYGTNCCNAAYCCNAGYATHCCNGAYGARATHTGGMGNGGNGTNGGN CAYYTNGCNGCNGGNGGNGGNGGNCCNMGNAAYCARTTYGGNYTNGAYTTYGCNGAYGCN GGNMGNGARTGGACNGCNGARYTNTGYAAYAARGAYTCNGAYGGNGAYGGNYTNTCNAAY GGNAARGARYTNGGNGAYCCNAAYTGYGTNTGGYTNGCNGGNGARCARCCNGARMGNACN ACNGGNATHTCNCAYCCNGGN------------------------ATHAGYACNATHATG TCNAARCCNTAYGTNTGGAARGTNAAYAAYGTNMGNTTYGARGGNTTYYTNAARGAYYTN ATGGAYAARGTNTCNGARGGNGCNGGNTTYAAYTAYACNTTYGTNGARCCNCARAARMGN GTNTAYGGNTCNGAYACNCCNAAYGGNTGGAAYGGNGTNATGGGNGAYGTNTAYAAYAAR GAYGCNCARATHGGNGGNCCNYTNACNGTNACNCCNGARMGNGARYTNGAYGTNGAYTTY ACNAARCCNTTYYTNTCNGAYGGNATHAAYYTNYTNGTNAARAARCCNACNTGGTTYGAY YTNGGNYTNGGNTAYYTNGTNMGNCCNYTNTCNTCNGAYTAYTGGATHATGYTNYTNGTN GTNYTNYTNYTNATHGGNYTNGTNTTYTTYATHATHGGNAARTTYAGYCCNTAYGARTGG GGNAAYGTNGCNGCNGAYAARGAYCCNMGNGGNGCNMGNAAYAGYTTYACNYTNAARAAY AGYTAYYTNTTYGCNYTNACNACNYTNTCNTGGCARGGNTTYMGNGARGCNCCNAARTCN YTNTCNGGNMGNACNATGGCNGCNTTYTGGYTNYTNTTYGTNYTNTTYACNYTNATHGCN TAYTCNGCNAAYYTNACNGCNTAYTTYYTNGCNMGNCCNGARCARATHCCNAAYYTNTCN TTYAARGAYGARYTNYTNGARTCNGAYATHGCNGTNATGGCNACNGAYTTYAGYTCNACN GARAARTTYYTNMGNACNAGYCAYAGYAARACNYTNMGNGARYTNTGGGGNMGNATGGAY AGYACNGGNGCNYTNYTNGGNTCNGARGAYGARGGNATHMGNAARGTNMGNTCNGAYGGN AARGARTAYGTNATGTTYYTNGARACNMGNAARGCNGARTAYACNGCNCARGAYGAYGAY TGYMGNYTNYTNGTNTAYGGNGARACNYTNTAYCCNAGYACNATGGCNTTYGCNGTNCCN AARGAYTCNCCNTGGMGNGAYATHATHAGYAARCARATHGARACNYTNMGNACNACNGGN YTNYTNGARGARATGAARAAYAARTAYTGGAARTTYGGNGGNMGNTGY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNYTNACNYTNTGYGTNTTYGCNGGNAGYACNTGYGCNGTN TTYTAYATHCCNGGNTCNGTNGTNAGYTAYCCNAARATGGGNAARMGNACNTAYTAYACN AAYGCNACNGGNAGYMGNTAYCCNYTNATHGGNMGNMGNTCNTCNTCNGGNGCNGARCAR GGNGGNCARGGNCARAGYTCNAAYACNGCNGTNGCNGGNGCNGTNGTNGARAAYGGNGAY GARTAYAAYAARMGNGGNGTNTTYACNCARGGNCCNCAYMGNAGYTAYCCNMGNGTNGGN MGNTCNGGNAGYTCNAGYGARAAYTCN------GAYTCNAGYGARAARATHMGNAGYGAR ATHYTNAARGGNYTNGCNGARMGNYTNAAYMGNAAYGTNATGGAYGTNYTNGGNAGYGGN TCNCARTCNGGNGARAGYATHCARTCNYTNAARGGNYTN---CARYTNYTNTTYYTNGTN TTYGAYGARGAYGGNGAYAGYCARYTNAGYAARGCNGARTTYACNTCNGGNYTNGCNAAR GTNYTNGARCARAAYYTNYTNTGY---------------CCNCARACNTCNYTNGAYGAY CCNGTNAAYGTNTCNGTNAGYYTNACNYTNATHAAYATHMGNGAYGTNGAYTTYYTNGCN AARGARGTNGARATHGAYGCNTGGYTNATGYTNMGNTGGAAYAGYGGNYTNMGNTTYGAY CCNTCNGAYTTYCARGGNATHGARTCNATHAAYGTNGARGCNTCNMGNYTNTGGMGNCCN GAYYTNGARATHTAYTTYGGN---------GAYATGMGNTTYACNAAYAAYGCNYTNGCN GTNYTNTCNYTNGAYGGNAGYGTNYTNTGGGTNCCNAARGTNMGNATGCARATHCCNTGY GAYGTNAAYCARTTYGAYGCNAARTCNGARGTNACNTGYAARATHAARYTNGGNTCNTGG ACNTAYAAYGARAAYTCNATHTCNYTN---AAYGAYAAYCCNACNGTNGAYACNTCNGAY TAYTCNCCNTTYTCNAGYTTYGARYTNATGAAYACNACNGCNGTNAARAAYYTNGTNCAY TAYCARTGYTGYGARGARGGNTAYGGNAAYATHGAYTTYGTNTTYTCNTTYAARAARAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGYYTNYTNACNYTNGCN TTYGCNYTNATHTAYMGNYTNCCNGTNCCNGTNGCNAAYTAYGARCAYTAYTGYGAY--- TCNAAYTTYMGNAAYCARMGNAGYGGNCARTGYGGNGARACNYTNGCNAAYACNGTNYTN AAYATGTGYMGNGCNYTNAGYAAYTCN------TTYYTNGGNAARTAYATHATGAARMGN GTNAAYCARAAYGTNGARAARMGN---YTNAGYGAYATHACNYTNAGYAARTCNGAYGCN TTYTCNTAYYTNTCNAARMGNCARGTNMGNCARAAYATHGTNTGYGARTGYTGYGTNAAY GCNTGYACNTTYACNGARYTNTAYCARTAYTGYGARYTNCCNCCNMGNCARGCNCCNMGN TTYATHGGNAARMGNCARGCNCCNMGNTTYATHGGNAARMGNCARGCNCCNMGNTTYATH GGNAARMGNCARGCNCCNMGNTTYATHGGNAARMGNCARGCNCCNMGNTTYATHGGNAAR MGNGCNGARGARACNGAYGAYAAYYTNGTNATHCAY---------ATHCAYAARMGNCAR GCNCCNMGNTTYATHGGNAARMGNGARAGYGTNTAYGARCCN------------------ ------------------YTNGGNGTNGCNTCNTGGGARYTNGGNGARTAYGAYAAYGAY TTYAAYAAYGGNGAYGAYGARTTYTAYGARGARGARGARGARGAYAAYGGNGARGTNAAR MGNGGNGCNCCNMGNTTYATHGGNAARMGNGGNCCNCCNMGNTTYGTNGGNAARMGNTAY CAYCCNMGNTTYGTNGGNMGNMGNGGNGCNCCNMGNTTYGTNGGNAARMGNGGNCAYCCN MGNTTYGTNGGNAARMGNAGYGARGAY---GARYTNAAYGCNTAYYTNYTNCARYTNGAR YTNYTNAAY---------------AAYATHTAYGAYCARAARMGNGCNGCNCCNMGNTTY GTNGGNAARAARAGYAARAGYMGNYTNGARGARAARGAYGTNCARACNTTYYTNGAYGAY TGGAGYMGNCARGARGCNATHAARAAYYTNGTNGCNAAYGAYAARAARTGGAGYAGYCCN GTNACNCCNTCNTTYATHGGNAARMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR YTNGTNTAYGAYMGNGCNTAYYTNATGGARYTNMGNGARTGYGCNTCNTCNCARGCNAAR CCNGAYGGNYTNCCNGCNYTNGARATHATHYTNGAYGCNCCNAGYCCNTAYATGCCNMGN TCN------ATGGGNCCNGCNGAYTTYACNCCNGCNTTYTTYAAYACNGGN---GCNAAY CARMGNCAYGCNCCNCCNATHGGNAARAGYAGYAGYMGNGGNMGNCARMGNCCNGGNGAY ATGCCNGGNACNCCNMGNGTNATHAARAGYATHTCNATGTCNAAYGAYACNAARCARYTN CAYCARAGYGAYAAYCCNTGGAAR---------CCNACNAARAARGARGAYAARGAYGAR YTNAARAARYTNGARGGNGAYATHYTNTTYATHATGAAYMGNYTNACNCCNACNAAYTTY GARAARYTNGCNYTNGARATGAARAGYYTNAAYGTNAARACNTAYGARGAYYTNCARTTY ATGGTNAARACNTTYTTYGAYAARGTNACNYTNGARACNAARTTYGTNGARGCNTAYGCN CARYTNTGYAARGTNATGTCNGGNYTNAARGTNACNCCNCCNGTNGAYGGNAGYGTNAAR GARAAYATGGCNACNTTYMGNGTNGTNATGYTNACNAARTGYCARCAYGARTTYGARGCN GAYAARTCNATHATHTTYGARGAYCCNGARGARAARAARAARAARYTNGARGCNGARAAY CCNGARAARACNCCNGARMGNGARGARYTNATHGARAGYACNYTNTAYCARATGAARYTN AARMGNATGAARTTYTAYGGNAAYATHMGNTTYATHGGNGARYTNTTYAARYTNGGNATG YTNACNGARAAYATHATGCAYGAYTGYATHTAYMGNYTNYTNAARGCNMGNGAYGAYGAY TCNYTNGTNTCNYTNTGYAAYYTNYTNACNACNGTNGGNMGNAAYYTNGAYACNGARAAR GCNAARCCNMGNATGGAYCARTAYTTYTCNCARATGTCNAARATHGCNGAYGARMGNAAR TCNMGNATHAARTTYACNYTNMGNGAYGTNATHGARYTNMGNCARAAYAAYTGGGTNCCN MGNAARCARGCNACNGGNCCNAARAARATHGAYGARGTNCAYAARGAYTTYGCNCARGAR CARGCNMGNAAYCARTAYYTNGCNTCNCARGCNYTNYTNCCNMGNAAYGAYAGYTCNCAR GCNGGNAGYMGNMGNGGNAGYMGNCARMGNCARGAYGARAAYAARATGGGNGARGAYGGN TGGAAYACNGTNGGNAAYCCNAARTCNTTYMGN---ATHGAYGCNTCNAARATGAARATH TCNAAR---AAYGTNGTNGAYGAYAAYATHCARYTNGGNCCNGGNGGNGGNGCNCAYAAR ---CCNATHTGGAGYMGNGGNAGYCAYGGNGGNACNCARCARCCNTCNCARGAYGAYMGN CCNGCN---YTNGGNAAYMGNTTYTCNGCNYTNACNAGYGAYGAYGCNMGNMGNTCNTTY CCNMGNTCNCCNTCNMGNGGNGARGGNTCNGCNGGNMGNAGYYTNMGNCARGGNCARACN GCNGGNCAYGGNMGNGGNAARATHATGTCNMGNTCNAGYCARGARGGNGARMGNMGNGAY GCNATHGCNAAYACNMGNTCNTTYATGGGNGGNMGNTCNCARAAYTCNAGYMGNGAYAAY AGYTGGAAYMGNGAYGAYMGNMGNCARTTYATGGGNCCNMGNAGYTCNTGGGARMGNGAY AAYCCNATGACNMGNAGYGAYAGYGCNGTNMGN---ACNGARGARTTYAARACNCCNGCN CCNCCN------GCNGTNAARCARATGTCNGARTCNGARGTNGARAGYAARGCNGTNAAY ATHYTNGAYGARTAYYTNAAYATHMGNGAYYTNGARGARGCNAARYTNTGYGTNAARGAR YTNACNGGNCARAAYCAYYTNCAYTTYYTNGTNACNGCNAGYATHAAYAAYGTNYTNGAR AARMGNGARGAYGCNMGNCAYATGACNGGNAAYYTNTTYAAYGARYTNGTNAARAAYAAY ATHATHTCNGTNAGYACNTAYATHAARGGNYTNAAYGARGTNYTNGARTAYGCNAGYGAY ATGGTNGTNGAYATHCCNACNYTNTGGAAYTGYYTNGCNCARGTNATHTCNCCNYTNYTN GTNGGNGGNTCNYTNCCNTGGTCNAARYTNAARCARGCNTTYACNCCNCAYYTNGAYAAY MGNGAYGGNGCNAARYTNATGGCNGCNATHYTNTCNYTNGGNGTNGARAARCARGGNGAR AARGARATHGCNCARGARTGGATHAAYAGYGGNYTNAGYTGGTCNACNTAYYTNAARGGN GAYGARYTNAAYTCNTTYGTNTCNGAYAARAAYYTNGGNTTY---ACNYTNGGNACNATG TCNGGNAGYGCNGGNATGYTNCCN------------------------------------ GAYYTNGARAARATGATHMGNGGNMGNGCNTCNAAYATHGARATHATHTCNTAYATHGAR AARATGGTNCCNGGNGGNAARACNGAYTCNGGNTTYATHMGNGCNYTNACNACNGCNATH ATHAGYTCNTCNATHAGYGARAAYAARAGY---------ATHAAYGARGAYATHATHAAR AAYCAYAARGAYGTNYTNCARMGNTAYYTNGGNAAYTCNGTN---GAYYTNCARYTNCAR GCNYTNTAYGCNATHCARACNYTNATGGTNAARYTNGARCAYCCNTCNGGNGTNYTNGCN AARGTNTTYGARYTNYTNTAYGAYGARATHTCNATGGARGARGARGCNTTYTAYMGNTGG GARAARTGYAGYGAYCCNCARGARCARGARGGNAARGGNACNTGYGTNATGCARGTNMGN CAYTTYTTYATHTGGYTNMGNGARAAYGARGARCCNGAYACNGARTCN------------ ------------------------------------------------------------ ---------------------------------------AGYTGGTTYGAYGAYYTNGAY CCNGAYYTNTCN---GGNGAYCCNYTNGGNGAYGAYAGYATGGARGCNTTYATHAAYYTN GAYAARTTYYTNAAYGGNAAYTCNTTYTTYGAYGAR------GAYGGNAAYYTNACNGTN GTNAAYCARGARGCNGARGTNACNCCNGTNATHAAYTTYGCNCCNGARGARACNCARAAR GARCARAAYYTNYTNACNGGNTTYGAYTAYAAYCARGAYTTYYTNYTNTCNCCNGARAAR AARCCNTCNMGNAARMGNCCNGCN---GCNTCNMGNGAYGGNYTNAARACNAGYYTNTAY GARATHCCNGCNACN---------------TCNYTNATHCCNGARATHATHCARTCNACN ACNYTNTCNGAYACNGARYTNGAYCAYGAYTAYAGYACNAARMGNCARMGNATGTCN--- ------------GTNCCNGARGGNAAYGAYAAYACNCCNTCNACNAGYGTNACNATGMGN AAYTTYACNCARTTYGARACNGGNATHCCNAARAARGTNGTNAARAARGARTCNAAYGAY AAYCCNGTNCARYTNYTNGAYGAYAGYATGGAYAARCARACNATHMGNMGNATHAARAAY AAYCAYGCNTCNAARMGNTCNMGNGARCARMGNAARCARAARTTYGCNGARATGGAYGTN GARGCNGARGARYTNGTNGTNMGNAAYCARCARYTNMGNGARAARATHGTNGARYTNGAR AARYTNGCNAARGARATGAARGCNGTNYTNGTNGCNAARATGGCNGGNMGNGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ---TTYYTNGCNCCNCCNTCNCARGAYGGNTTYTAYTCNGCNGCNGCNGAYTTYGTNACN GARTTYAARTCNGARAARATHMGNCCNCAYTGGGCNAARMGNCAYGAYACNATHGTNGGN ATHGTNCARCARATHCAYGAYGTNTAYGGNAARAAYYTNGARGARTTYAAYMGNCARMGN MGNYTNGCNGGNGTNGAYCCNTGYGAYATGTTYATGAAYGGNTAYYTNYTNACNATHTTY GGNMGNAGY------------------------ACNAARAGYGARGAYGAYGGNGCNGAY ACNGCNGAYTCNAARGTNTCNTCNTCNTTY---------GGNGCNCAYGCNMGNCCNTTY TCNGAYTCNGCNTCNTCNGCNCARGAYGGNAAYCARGARGTNAGY---AGYTCNGAYATH ACNGARTCNGGNTGYYTNTCNCAYCCNCCNAARGTNGCNTCNATGAGYCCNTAYAGYAAY GCNTTY------TAYGGNAAYACNCAYAAYGCNGGNATGTAYACNAAYCCNTTYGTNCCN MGNGCNCCNYTNAARTCNGAYGTNGTNTCNACNGAYCARTCNAAYAGYACNGARAGYMGN GARGGNYTNATHGCNCCNAGYMGNYTNAAYGCNGCNGTNAAYMGNGAYAGYTCNGARGTN GARGGNAAYMGN------TCNTTYCCNAARCARTCNGTNYTNGCNCCNCCNAARYTNACN GGNGCNGTNTTYGGNGGNGGNAGYGCNAGYCAYGAYACNCCNAGYTCNACNTTYAAYTCN TTYAAYTCNTAY---ATHMGNCCNTCNGTNTTYTCNGGNCCNTTYGAYTCNCCNGGNYTN GGNMGNGGNGCNCCNYTNYTNAARCCNGCNAARYTNCCNGAYCCNACNAARTCNTGYGAY AGYAARGCNGAYTCNGCNAGYGARGCNGAR------GTNYTN------AAYGCNAARTCN GGNGARGCNTCNTCNGCNAGYGAYMGNYTNGGNGGNGCNGAYGGNACNTCNGGNGGNAGY GARGTNTCNTCNTCNTCNGCNTCNTCNTCNYTNCCNCCNCCNACNCCNCCN--------- GAYGCNGARGGNGCNGTNGGNGGNGARAAYACNCCNTAYAAYCARGAYATHGTNCCNGAY ATHAAYAARAAYAAYMGNYTNAARGAYACNTCNGGNGTNTCNAGYAGYTCNCARTCNTTY GTNTTYGGNAGYAAYYTNTCNCARMGNGTNACNGGNATHYTNTCN---TCNCCNTTYGAR AAYGARGCNTCNGCNTCNTCNGGNTTYGTNTTYGGNGARTCNYTNGGNTCNMGNGCNGTN GTNGARACNAAYGGNTCNACNCARTCNCAYAARGAYGAYGARAGYGAYTCNGAYTCNGGN AAYAARYTNAAYMGNACNYTNGARGARTCNGCNMGNGARTAYCARGCNAARCAYGARATG AARACNGARYTNAARGARGTNGARACNATHACNGGNGARGARGARGARTCNAAYGTNYTN CARGCNAAYGGNAARYTNTTYTTYTTYGARACNAGYAAYGARTCNTGGGTNGARMGNGGN MGNGGNACNATHMGNYTNAAYGAYATGTCNGCNMGNGAYAAYACNAAYTTYCARTCNMGN YTNGTNATGMGNACNCARGGNAGYYTNMGNGTNGTNYTNAAYGCNAARATHTGGCCNGGN ATGTCNYTNGARMGNGCNTCNTCNMGNTCNATHMGNATHACNGCNATGGAYACNGAYGAR TCNATHAARATHTTYYTNATHACNACNAAYATHAARGAYTCNGARAAYYTNYTNMGNGCN ATHGAYTGGMGNATHCARCARYTNAARATHCARGARGARCCNGTNMGNCARCAYTCNGTN TCNMGNACNGGNGAYAARMGNAARGCNGARGAYTCNGAYTTYGARTTYCCNATHAARAGY AARAARGTNAAYAGYTCNCCNGAYCARGGNATHTCNATHACNAARAARGARGARTCNGAY AGYAGYGTNCARGAYCCNGARACNGARGCNTCNTGYGARAGYCAYTCNTCNTCNYTNACN ATHAARTCNGARTCNGAYTTYCARTGYATHCAYTGYGGNTGYAARACNGARAARYTNTAY CAYGAYTAYAARGCNGGNATHACNAARGTNACNAAYTGYAARAAYTGYGGNAAYATHGTN GAYAARTAYGTNGARTAYGAYTCNGCNATHATHYTNYTNGAYGTNYTNYTNYTNCARAAR CARGCNTAYGCNCAYYTNYTNATHAAYGTNGARGTNAARTCNCAYTGGAARTTYGCNGTN YTNYTNTGGGTNGTNGARGCNTTYATHAARYTNATHCARCARMGNTCNGARCAYGCN--- ---------AAYTCNTAYCCNGGNGCNAAYTAYTGGYTNGCNGGNGTNGARYTNTAYYTN AAYTAYYTNGGNGCNGCNGTNGARYTNATGAGYTTYYTNYTNTGYGTNGTNGCNYTNYTN GCNATHMGNAGYYTNTTYYTNACNMGNAGYYTNAAYYTNYTNAAYACNTTYYTNATHACN AARGCNATHYTNYTNTCNAAYYTNGGNTCNYTNYTNGCNATGCCNGCNYTNTTYTGGGGN AARTCNTGYAGYCCNATGTTYGCNTGGYTNGGNCARGCNTTYGTNTGYYTNTCNTCNYTN CARGCNYTNMGNGTNGTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNAAYAAYGAYAARGAY YTNGCNGTNTGYCARAARGARATHAARATHGCNAARGAYYTNAGYGGNCAYAARAAYATH ATHMGNTAYATHGARTCNAGYATHACNGTNACNCCNAAYMGNGTNTAYGARGTNYTNATH YTNATGCARTAYTGYMGNGGNTCNGTNATHAAYGCNATGAAYGAYMGNATHAAYACNGGN TTYTCNGARCARGARGTNYTNMGNATHTTYTGYGAYGTNTGYGARGCNGTNTCNMGNYTN CAYCAYTGYCARACNCCNATHATHCAYMGNGAYYTNAARYTNAARCARTAYGCNGCNACN GARTAYYTNMGNACNGARGGNACNCCNCCNATHAARATHCARMGNMGNYTNAARAAYGTN TAYGGNGAYGARTCNGTNAAYGTNAGYACNATGGTNMGNTGGGTNMGNMGNTGGAAYGGN GGNAAYCCNACNGARMGNAAYYTNCARAAYCARTTYTGYTGYGGNMGNATGGCNTCNTCN AAYGTNTCNMGNACNYTNGTNAARTCNYTNAARGGNMGNACNTTY---TCNGCNGCNGCN GCNCARGCNGAY---MGNGCNCAYYTNGAYAGYTCNCCNAARTGYTCNGTNAARAARYTN AGYAAYGGNATGACNGTNGGNGTNATHTCNTCNAAYTCNCCNGTNTCNMGNYTNGCNGTN GTNGCNAAYGCNGGNTCNMGNTTYGARAAYGGNGAYAAYYTNGGNATHTCNCAYTTYYTN MGNATGTCNTCNMGNYTNMGNACNGARAAYATGACNAGYTTYGGNATGACNMGNACNGTN CARCARYTNGGNGGNGAYYTNACNATHATGGGNACNMGNGARTAYATHTAYTTYAARACN AGYGTNACNMGNAAYTCNGCNGAYAARGCNGTNAARGTNYTNGARGARYTNACNACNAAR CARGCNTAYMGNGGNTGGGARGTNACNGAYGTNCARAAYGAYAARAAYGGNATGATHYTN GAYYTNGCNYTNTAYCARACNMGNCCNCAYGTNCARGCNGTNGARYTNYTNCAYTCNGCN GCNTTYMGNAAYACNYTNGGNAAYTCNYTNTAYGCNCCNGARCAYAARATHGGNCARTAY ACNCCNGARCARATGATGCARTAYGTNAARACNTAYTTYAGYGGNGGNMGNATGGCNYTN ATHGGNGTNGGNGTNGAYGARGCNYTNYTNGARGAYYTNGCNTCNTCNTTYCARCCNTTY GCNTCNGCNGGNGTNCCNGTNGARAARTCNGCNTAYTAYGGNGGNGGNGARATHMGNCAR AAYACNGGNGGNGARGTNTCNTAYGTNGCNGTNGGNTTYGGNGGNCCNAGYYTNACNAGY AARGARYTNYTNGCNTCNGARGTNYTNMGNCAYATHYTNGGNACNGGNCCNCAYGTNAAR TAYAGYAGYGGNACNACNGGNGCNCARYTNGCNAARGCNGCNGCNGGNGCNACNGAYGCN CCNTTYCAYGTNTCNGGNYTNAAYGTNAAYTAYAGYGAYAAYGGNYTNTTYGGNTAYACN GCNGTNGCNCAYGCNTCNCARATHGARAARGTNYTNCARGCNGCNGGNAAYCARTTYAAR GGNATHYTNTCNTCNAAYATHTCNGAYCARGAYGTNGCNAARGGNAARAAYCARYTNAAR GCNGARATHTGYATGCARTTYGARAAYCCNGAYATHYTNYTNAAYTGGYTNGGNGARCAR GCNYTNAAYAGYGARGARYTNGTNACNCCNGARGAYATHTAYAARATGGTNGAYAAYATH AAYACNAAYGARGTNAARACNGTNGCNAARAGYATHYTNAGYTCNMGNCCNTCNATGGCN GCNGTNGGNAAYATHGCNAAYGTNCCNTAYYTNGAYAARYTNATGGGNGCNAARGGNAGY AARCARAARAGYAARAARAAYAARAARGGNGARGAYGARGCNGGNAAYGARGARGCNCAR GARCARCARCARGARGCNGGNGAR---GGNGCNTCNGARCARAARGAYAARGTNGARGAR AAYGGNTCNGCNGCNAARGTNGARGARGGNGGN------GARGGNGGNGARGCNAARGAR GARACNAARAGYGAYGARCCNGCNGCNGARGCNAARTCNGARACNGCNGARCCNACNCAR GARGARACNGARAARCCNTCNGARGARTCNACNGCNCCNTCNCCNAARGCNGARGARCCN GCNGTNCCNGARCCNGCNAARGARGARCCNGTNGCNGCNCCNGCNGARGARCCNAARGTN GARGARCCNAGYGCNGAR---------------GARAAYAARGARGARCCNGTNCCNGCN CCNGCNGCNGARGARCCNGCNGARGARCCNGCNAARGARGARCCNGCNAARGARGARGAR CCNGCNGARGCNCCNGARCCNGTNGARGARACNCCNGCNACNGCNGARGARCCNTCNGCN CCNGAR---GARACNCCNGCNCCNGARCCNGARGTNGCNGARACNCCNGCN--------- ---GCNGARGARACNTCNGCNGCNGARGARGCNCCNGCN--------------------- ---GCNGARGARTCNGCNGCNCCNGCNGARCARGTNCARACNCCNACNAARAARATHCCN AARYTNGCNCARACNGTNAAYAARGCNMGNGGNATHYTNCAYTTYTCNMGNGAYMGNGAR TCNGGNTCNCARAGYYTNAAYGAR---GARAGYGCNCCNGCNACNCCNTCNGAYACNGCN GARACNGGNGCNGCN---------GAYGGNTCNTCNGCNGARACNGGNGARACNGCNGCN ------CARGARTCNACNCCNTCNACNGTNMGNACNGARTTYAARTGGGARAAYGGNGGN GAYACNGTNYTNGTNAGYGGNACNTTYAAYAGYTGGCARGARAAYATHGCNYTNTCNAAR GARGGNGAYATHTTYACNGGNTTYATGGAYYTNCCNGTNGGNGARTAYYTNTGYAARTTY ATHGTNGAYGARCARTGGGTNGTNAAYAARAAYYTNCCNATHMGNTCNGGNGARGAYGGN CARGARAAYAAYGTNATHYTNGTN---------AARTAYGCNCAYTTYATHGTNTGYTTY ACNGTNTTYATHGTNACNATHTCNACNGTNGGNAAYTTYCARYTNTTYGTNTCNAARCAR TCNYTNAARTAYTGGGAYAARGAYGCNACNGTNATHGGNTGYTTYYTNTGGGAYTTYGCN YTNATHTGYYTNTTYGTNTGYCARCAYTCNYTNATGGCNACNCCNTGGTTYAARAAYCAY YTNCARTCNTGGTGGMGNATHTCNGTNTCNGARMGNYTNYTNTAYYTNTGYACNACNTGY ATHTGYYTNATGGTNATGATHYTNTAYTGGCAYAGYATHCCNGARGTNTAYYTNTGGTAY ATHGAYACNCAYGAYMGNATHTTYYTNTGGACNTTYTTYYTNYTNTGYCAYTTYGTNGGN TGGYTNATGATHGGNYTNGARGTNATGYTNATGGAYGTNGGNGARYTNYTNGGNTTYACN CARGTNCARAAYTAYCAYAAYGGNYTNGCNCCNCCNYTNYTNAARAARAARGTNGCNAAR YTNMGNGARATHTAYTCNAAYATGMGNCAYCCNGGNGTNGTNATHYTNACNGTNYTNYTN TGGTTYTAYCCNYTNATGACNYTNGAYMGNGTNYTNYTNGCNTCNYTNTTYACNTCNTAY ATGATHTGGMGNCAYAGYYTNGAYGAYTCNCAYTGYGARTAYGCNGARAARCAYTTYMGN TCNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHGAR GGNMGNGCNATHCCNCCNMGNACNATHYTNGAYGCNGTNGARGARAAYAAYATHATHTTY AGYCCNMGNYTNTTYCARATHTTYCARCCNCCNACNYTNYTNMGNCCNCAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYMGNTGGTTYATGGAR AAYGTNGCNTAYGAYGTNTAYGGNGTNTAYTAYTGYCAYGGNCARGGNGGNAAYCARYTN TTYMGNATHAAYTCNAARGGNCARYTNGGNYTNGGNGARMGNTGYATHATGGARGARAAY MGNGAYACNYTNCAYATHCAYGTNTGYTCNATHCARCCNGAYGGNCCNTGGGCNTTYGAY AARGCNACNGGNGCNATHMGNCAYACNTCNYTNAAYAARTGYGTNGGNACNACNATHGAY GAYAARYTNCAYYTNCARGCNTGYGAYGARACNGCNYTNAAYCARCARTGGGARATHAAY GARATHTAYCCNTGGAARTGGMGNACNAARTGYATGAARYTNGARGARGTNATHAARACN YTNTCNAAYCAYTGYGTNMGNGTNGTNGARCAYCAYGARGAYYTNYTNGTNAARTTYAAR AARAAYCARGARCARTAYGARMGNYTNAARACNAARTGYAARGARMGNGGNGARCARATH AARCARGCNMGNGCNGTNYTNATHCCNGTNTCNAAYGARYTNAARATGYTNMGNGARAAR TAYGARATHGCNGTNMGNTGYCARATHGARGCNGARTCNTTYGCNATHCARACNACNAAY AARAAYAARAARYTNAAYMGNCARAGYCARATHATHATGGCNAARYTNGGNGCNGCNAAY ATHGTNGAYATHAAYATHGAYGAYGAYCCNGAYCARGGNGARGARGARAARAARTAYATH GARAARYTNGGNCARCARATHGARGAYYTNGARAAYGARAARAGYACNYTNAGYATHCAR GTNAARGARATHACNGARAAYTTYCARGAYGARAARGARGCNAAYGARCAYYTNAARGGN MGNATHGARGCNATGAARGARGARYTNCARCARGCNAAYGTNGCNATHACNGARCARACN GARYTNYTNCARAARGTNGCNGTNACNTCNGARATGGCNTAYAARGARTAYMGNGAYYTN GARCARACNTGYMGNGCNGARTAYGTNGTNMGNAGYGARGCNGARMGNTAYGTNAARAAR YTNMGNACNGARMGNGAYCARGCNMGNMGNGARAGYTCNATGGCNYTNAGYCARGTNGCN GAYAAYAARAARYTNATGGARGCNATGYTNGARATHCARGARYTNAAYGCNCARTCNGTN AARATGAARGARGAYTTYGAYAARAARATHAGYGAYYTNGARGARCARYTNAARGCNGCN AARGARGTNTAYAAYGCNGARAAYYTNGARGCNGARAAYGARGARYTNAAYACNGARAAR AAYACNYTNCARGARAARYTNGARAARMGNGARTCNGARATGGCNGAYYTNMGNACNAAR TAYACNGARYTNCARGARACNTAYAARAARYTNGARACNAAYTAYCARAARGTNACNGCN ATHCCNGTNCCNCCNCCNCCNCCNCCNCCNCCNCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TCNGGNGGNATHGAYTAYGGNTAYYTNATHATHGAYGAYTGYTAY AGYCCNGTNMGNGTNTCNAARYTNYTNYTNGAYGCNYTNGAYAAYAGYGTNMGNATHGTN GAYAARTCNACNGGNGARYTNTTYAARCCNGARAAYGTNTGGGCNGTNATHGGNGCNYTN ACNAGYCCNAGYACNATHGCNATGYTNTCNCAYGTNMGNGAYYTNTAYATHCCNGTNATH TCNTAYAGYGCNACNACNCCNAGYYTNAAYGAYAARATHYTNTAYCCNTAYTTYTCNMGN ACNYTNCCNAGYGAYACNYTNCARGCNCARGGNGTNGTNGARATHATHAARTAYATGAAY GCNACNCAYGTNGGNGTNATHGCNYTNGAYAAYATHTAYGGNYTNGARYTNYTNMGNYTN TTYGTNGARAARGCNGARAARCARMGNATHTGYGTNGARGARGCNYTNATHGCNAAYGAY TAYACNAAYATGGCNGAYATHGAYAARAARYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GARMGNTAYATHAARAARCARCARGARMGNGCNAARTCNCCNAGYAAYCARATHAAR GTNGTNAARCCNCARCCNGCNGCNCARCCNGTNYTNCCNCCNACNCCNCARCCNAARGGN GCNACNGTNAAYACNTTYACNCCNACNTCNGTNYTNGTNAARATGCAYTCNGAYAARGCN ATGGARAARGARAARCARGCNCARGAR---ATGGGNGAYAARTTYGTNGARTTYATGCCN TCNATG------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TTYGARGAYAGYGCNGGNAAYGCNYTNCCNGTNCAR GARAGYTTYAARCCNTCNCAYAARCARYTNTAYCCNGGNATHYTNTGYGGNTCNTTYTAY MGNGAYATHATHCARCARTGYTTYCCNCARATGGTNAARAAYTCNGTNTTYTGYTTYGAR ATGTTYATGATGCAYYTNGGNAGYGTNCAYCCNCARTAYATHGCNTCNCAYTGYAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ACNAARATGAARMGN TCNGARMGNCAYATGATGMGNYTNAARAGYATHATHGCNAARGTNYTNGCNGARAARGGN GTNGARAARGGNGAYCCNATHTAYCARGCNTGYTCNCARAAYYTNYTNAAYGTNAGYATH GTNYTNYTNAARAGYYTNTCNCAYTCNMGNAAYYTNACNGAYGARATGAARTCNGTNGTN TAYGGNCARGTNCARCARATHATHAAYYTNGARAARMGNMGNTCNGGNATHTCNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------MGNAAR MGNAGYMGNAGYMGNGARMGNMGNMGNTCNCCNAGYMGNGARMGNAARTCNMGNAGYAAR AGYMGNGARMGNMGNMGNMGNGARGAYMGNGAYAARGGNMGN---MGNMGNAGYMGNAGY AARAGYMGNGARMGNAARMGNAGYMGNAGYAARAGYMGNGAYMGNMGNMGNAAY---AGY MGNAGYMGNAGYMGNGARMGNMGNMGNMGNAGYMGNTCNCCNMGNMGNMGNTAYAGYMGN AGYCCNYTNMGN---GARMGNYTNCCNGARYTNACNGTNGARGARMGNGAYGTNMGNACN ATHTTYTGYATGCARYTNTCNGCNMGNATHMGNCCNMGNGAYYTNGARGARTTYTTYTCN TCNGTNGGNAARGTNMGNGAYGTNMGNYTNATHACNGAYAAYAARACNMGNMGNTCNAAR GGNATHGCNTAYGTNGARTTYGCNGAYCCNGARTCNGTNACNYTNGCNATGGGNYTNACN GGNCARAARYTNYTNGGNGTNCCNATHATGGTNCARCARTCNCARGCNGARAARAAYMGN GCNCARCCNGCNACNCARGCNCCNGCNCARAARCAR---GCNCCNGARGGNCCNYTNMGN YTNTAYGTNGGNTCNYTNCAYTTYAAYATHAAYGARGAYATGYTNMGNGGNATHTTYGAR CCNTTYGGNAARATHGTNGAYATHAARATHATGMGNGAYCAYGAYACNCARMGNTCNYTN GGNTTYGGNTTYATHAGYTTYGCNAAYGCNGAYGAYGCNAARAARGCNYTNGAYCARYTN AAYGGNTTYGARYTNGCNGGNMGNCCNATGAARGTNGGNCAYGTNACNGARMGNACNGGN GARCARGGNCARGGNCCNCARAAY------GGNGTNGGNGGNCARYTNGAYACNGAYGAR ATGGAYMGNGCNGGNATHGAYYTNGGNGCNACNGGNMGNYTNCARYTNATGGCNAARYTN GCNGARGGNACNGGNTTYCARATHCCNCARTAYGCNGCNAGYGCNYTNAAYAAYATGACN CCNGCNGCNGTN------------------------CCNGGNGTNCCNGCNGCNGCNGCN GCNGCNGCNCCNGCNGCNCCNGTNGCNAAYCCNYTNGCNATGCCNCCNGCNGTNCCNACN ACNATHGCNACNAAYGCNCCNCCNATHGCNACNCARTGYTTYATGYTNTCNAAYATGTTY GAYCCNACNTCNGARCCNMGNYTNACNTGGGAYCARGARGTNMGNGAYGAYGTNATHGAY GARTGYAAYAARCAYGGNGGNGTNYTNCAYATHTAYGTNGAYAARAAYTCNCCNCARGGN AAYGTNTAYGTNAARTGYCCNAGYATHTCNGCNGCNGTNGCNTCNGTNAAYTCNYTNCAY GGNMGNTAYTTYGCNGGNMGNGTNATH--------------------------------- ---------------------------------------------------GARGARYTN MGNTCNTCNACNATGTCNYTNAAYAARMGNAGYATGGTNATGGAYGARGAYMGNTTYGAR GAYCARTTYYTNMGNTGYAGYATHTGYAARMGNMGNTTYAGYCARGAYAAYYTNCCNMGN YTNYTNCCNTGYCAYCAYTCNTAYTGYCARCCNTGYGTNYTNCARYTNTAYCARACNGCN AARGARCARMGNCARCAYYTNCARTCNTCNYTNMGNACNATHACNTCNACNYTNACNACN GTNAGYGTNAAYTGYCCNACNTGYMGNTCNAAYTTYATHGCNACNGAYGAYAAYATHCAY AARYTNCCNGCNGAYCAYMGNGTNGTNCARYTNATGGAYTTYGTNAAYCAYACNGARMGN TAYACNATHTCNTTYTGYTCNAARCAYAAYYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYATGTTYTGGTAYYTNTTYYTNGAYAARTTYCARCCNAGY CARAAYTAYCARGCNAARYTNTTYAAYMGNATHTCNCAYAAYTAYGTNAARYTNATGATG ATGACNGCNGAYCCNATHGCNAARGAYACNTTYTTYAARGAYTAYCCNAARYTNATGTCN CARGCNYTNTAYGCNTCNTTYTGYTTYTGYTTYCCNGAYTCNTAYMGNCARTTYGGNGAR AAYTTYAARGAYCARYTNGTNTAYYTNGTNTAYGGNTGGATGGCNGGNATHMGNCCNGCN CCNMGNAGYTGGATHACNTGGGAYATGTCNAAYYTNGARCCNCCNAAYYTNAARATGMGN GARGARATGATGCARAARAARAAYAAYAARAARATGACNTCNTTYATHGAYTTYGAYTAY YTNGAYTCNYTNATHTCNACNAAYGCNAGYCARTAYGCNTCNACNATGTCNYTNGCNCAR TCNACNTCNAARTCNTCNACNACNTCNAAYYTNGGN---CCNGCNMGNAARCCNMGNATG CAYGCNMGNATHAGYAAR---CARCAYAARCCNYTNTTYMGNACNTCNTCNCCNAAYAAR GCNCAYTCNCCNAAYTTYTCNCARGAYTCNAAYYTNATHGAYGTNGTNGCNGAYGCNCAR AAYAGYCCNMGNGCNAARGGNMGNGAYACNAAR---MGNGGNAGYGARTCNYTNACNCCN GCNMGNGAYYTNAARMGNCARAGYGAYGCNYTNACNCCNATHMGNGARATGACNAGYGAR GAYGARGCNGARGAYTTYGGNAARAARTTYTCNCARGTNTCNATGAGYCARATHMGNGAR AGYMGNAAY---AARAARGARCAYGTNGARTCNCAYCCNATGGGNMGNGGNTGYGARTTY GTNMGNACNGCNTTYAAYGTNGARGGNMGNAGYCCNYTNGTNGCNCAYTTYYTNAAYGTN AARGGNYTNACNCARGAYGTNGGNCARAAYATHTGGATHCARMGNGTNGARATHGAYGAY YTNCCNCCNYTNGAYGCNGCNACNTAYAARGAYGTNATHAGYGARTCNTCNAARACNATH AARAARYTNGARTCNGGNTTYCARGAYYTNTAYYTNAARAAYTAYAARCAYAGYCARATG TTYATGMGNCARCARCARAARATGYTNMGNGARCAYATGCAYAARCARTCNGCNYTNYTN GCNAAYAARGARGARGTNAARGTNYTNTGYGAYYTNATHATHYTNGARCARMGNAARAGY CARGAYTCNGTNTCNGCNGGNGCNTCNGCNGCNATHGARGCNGCNYTNATGGCNCARGAR ---------------------------------------TCNGARGARGARAARCARGTN CAYTCNGAYTTYTTYGAYGGNMGNCCNCCNAARACNCCNGARMGNTAYYTNAARATHMGN AGYTAYATHGTNGAYTGYTGGYTNAARAAYAARCCNATHTAYYTNAAYAARACNTCNGTN MGNCCNGGNYTNAARAAYTGYGGNGAYGTNAAYTGYATHGGNMGNATHCAYGCNTAYYTN GARTGYGTNGGNGCNATHAAYTTYGGNTGYGARCARGCNGCNTAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARATHATHCCNCCNAARGARTGGGTNCCNMGNAARTCNGGNTAYGAYAAYATH GAYYTNGTNATHCCNGCNCCNATHGARCARGTNGTNTCNGGNCAYCARGGNYTNTAYACN CARTTYAAYGTNCARAARAARGCNATGAARGTNAGYGAYTAYGARAARATGGCNAAYTCN ACNAARTAYMGNTGYCCNAAYCAYTTYGAYTTYGAYGARYTNGARMGNAARTAYTGGAAR AAYATHACNTTYGGNCARGCNATHTAYGGNGCNGAYATHAGYGGNACNATHACNGAYAAY GAYCARGAYGTNTGGAAYATHAAYMGNYTNGGNTCNATHYTNGAYCAYGTNAARAAYGAY TAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGCNGARACNGAYGTNCARMGNYTN YTNGAYYTNCAYAARTCNYTNGTNYTNGAYGARAARACNCARAARATHAARTGYAGYYTN ACNAAYCAYGARATGCCNGCNAARGCNAGYGCNATHGARAGYTAYGTNAGYGGNAARAAR TAYAARMGNYTNGCNGAYYTNAAYACNTTYYTNTAYGGNGAYCAYAARGARCAYATHGTN CARAAYAARAARAARGAR------AAYGARYTNTTYTGYAAYYTNACNYTNCAYCAYYTN GARAARACNGCNCARGCNATHCARMGNCAYATHAAYGGNMGNAARTAYAARAAYGCNYTN GCNMGNTGGAARGARTGYCARAARACNGGNACNAARTTYACNCCNAARATH---CARMGN AARGCNAARGGNCCNAAYCAYGAYGGNACNGTNGTNGARGAYGGNAGYTCNGAYGAYGAR GAYGAYGTNGAYGARGARGARGAYGAYGAYGAYATGAGYGAYYTNTAYCCNGCNGCNGAY TTY------------------GARGARYTNAGYGAYGARGAYGARGAYGGNGAYGARAAR GARAAYGARGARGARGAYGAYGARGARGAYGARGARGARGARGARGARGARAARGAYAAY ACNAARAAYAARAARACNGTNGARAGYAARAARACNAARMGNACN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GGNACNTAYCCNGARGTNYTNAARAARGTNMGNGAR GARYTNAGYGAYTTYGGNYTNTTYGGNCARGAYGAYTCNGCNGARYTNAGYTAYGAYYTN YTNCARAARYTNGARTAYGTNCAYTGYGTNATGAARGARTCNTTYMGNTTYATGCCNCCN GTNGGNGGNTGYTTYMGNAARACNGARAAYGARATGAARYTNGGNAARTAYACNATHCCN AARGAYTGGACNGTNGTNTTYAGYATHMGNGAYACN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNYTNGCNGCNTTYAARAGYYTNCAYMGNGCNMGNAAR GARGTNTTYGCNGGNGAYGTNMGNGCNYTNAAYGARGTNMGNCARCARATHAAYTCNCAR TTYMGNGARAARYTNCAYGARACNGAYGAYTCNAARATHGARGARAAYYTNATHYTNGCN AAYGAYGTNGCNTAYYTNYTNMGNTCNACNGTNGTNCARYTNCARCARAARGAYGCNGAY GAYGARACNTAYGARYTNMGNATHACNAARAAYACNTAYYTNCCNGARAAYACNCCNTTY GAYCCNYTNAARGARATGCCNGTNAARCARMGNAARAARAARACNTCNAGYTGYGARGAY TCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHATGAAYATHGARCCNGGNCAYTCNYTNTGGAARMGNGAR MGNGGNYTNCAYCAYGCNGGNGCNATHMGNGCNTAYATGAARGAYCCNMGNGAYAAYGGN ATHCCNMGNGGNCCNGAYGCNAGYCCNYTNYTNTGYCCNGARTGYGAYGCNAGYGAYAGY CARTAYGAYTCNTCNAGYCCNAAYAGYYTNGGNTGGYTNATHTCNCCNGGNGTNTCNTCN ---------------------------GARTGGYTNAAYTCNGAYCARGAYACNYTNCAR ACNYTNGGNTGYYTNGCNATHGGNAAYTTYGCNMGNMGNGAYTCNTAYTGYGTNGARYTN GTNGAYAARGGNATHGTNGGNAARYTNYTNCCNYTNYTNAARTCNGCNCCNGAYACNTCN TTYTAYYTNCARCAYGCNGTNYTNAGYACNYTNMGNAAYYTNGCNATHCCNGTNGCNAAY AARYTNMGNYTNYTNGARCARGGNGTNATGGARGCNTGYYTNTGYYTNAARAAYTCNGAR GTNATGGCNGTNATHTTYAARYTNYTNGGNYTNYTNMGNATGYTNATHGARGGNCARGAR TCNGCNGCNGTNAARYTNGGNCARGAYMGNGGNTTYYTNGAYTGYYTNTCNGARTGGTGY TCNGTNGARGTNCAYGCNGGNGTNAARGGNGARGCNCCNMGNGTNATHGCNTCNYTNATH AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGACNGAYGCN CAYMGNATGTTYYTNCARAGYTTYATGTCNAARGGNGTNATGAAYACNAGYGARGTNAAR GCNTGYTAYGTNCARTGYAARAAYAARTTYTCNGAYCCNGTNGAYGARGAR--------- ------AAYATGACNTCNCARATHCCNGAYTTYGTNMGNACNATHAAYTAYGCNATHTCN GCNTTYAAYYTNGARATHMGNAARGGNATHCARGARCAYGAYGGNTCNAGYGTNTAYTGY YTNGTNAAYACNGTNGARAGYGTNATHTCNMGNYTNTCNTCNACNTAYTCNCARAAYGAR YTNGARYTNTTYAARAARYTNGTNGARTAYATHGTNGARTCNGAYGAYGGNAARATHGGN TCNMGNATHGCNYTNAAYYTNACNGARAARYTNGARAARMGNATGGGNAARGARGARGCN CARAAYTTYTTYAAYAGYYTNGARAAYGARAARTGGATHGTNAARGAYAAYGAYGGNAAR ATHGCNYTNTCNGTNMGNACNYTNYTNGARYTNGAYCARTAYYTNCAYGARATGTAYCCN GARYTNATHAARGAYTGYAAYATHTGYAARAARYTNTGYATGCARGGNGARGCNTGYYTN AGYTGYGGNATHAARYTNCAYTTYAARTGYGGNAARACNTTYTTYTCNAARCARACN--- AAYAARAARTGYCCN------AAYTGYMGNYTNGCNTGG--------------------- ------YTNTCNGCNGCNGARAARGGNAGYGCNCAYAARGARTGGYTNMGNYTNAARTTY ACNYTNCARGTNAARTAYCAYAAYGTNACNCARCAYYTNTGGYTNYTNTCNYTNCCNTTY AAYATHMGNAARGGNTCNATHCARATGTAYACNTTYACNGGNGCNTTYYTNTGGTAYTAY TTYAAYGCNGAYCCNTTYAAR---GARTTYACNGTNCCNGGNTAYYTNCCNGCNTCNAAR GTNYTNGAYATGGTNATHACNMGNYTNGARGTNATHGGN---------MGNCCNYTNACN TCNGTNGCNAARAARTTYTTYGARGARMGNYTNAAYGTNMGNYTNGARACNGTNACNAAR AGYCCNCCNTCNACNAARACNGAYGARCCNGARGTNACNMGNACNGTNGAYGARGCNGTN GAYTAYTTYGGNTTYTTYACNTGGTTYTAYGCNYTNGTNAARTGYYTNGAYACNTAYYTN AAYAARYTNTGGYTNGARGGNTAYATHTAYGAYATHTGYGAYYTNTCNCAYGTNGARAAY ATHATHAARAAYTCNATGTTYGGNTAYCARAAYGTNATHATHMGNCCNTCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARTCNGARTGGYTNTCNGTNGTNCCNTCNYTNTGYMGNGARYTN AGYAARATHCCNCARGAYCAYTAYTGYTCNGTNTAYYTNGTNGAYYTNATGCCNYTNAGY GTNMGNGGNAAYTAYYTNCARATHMGNYTNAGYTTYYTNYTNYTNTGYTCNACNYTNGAY CCNGARMGNAARGAYGARCAYYTNAAYCARYTNGAYTCNGTNTCNCCNTCNMGNATHTCN CARYTNGGNAAYGARTCNCCNGARAGYCARCCN---AAYACNATHTTYTCNTGYTTYCAY MGNYTNATHAARGARGAYATHAAYAARATGAAYTCNGCNATHACNYTNYTNGAYMGNGCN GTNGGNGAYGARACNAAYMGNATHGCNCARTCNAARGAYGARYTNGAYTAYYTNACNAAY CARGTNAARATGGTNATHAARGAYATHMGNGAYAGYATHTAYACNYTNGAYYTNTCNAAR ATGAARGAYMGNATGATHATHATGACNAARAARTGGATGATGATGTCNACNCARTGYACN AARAGYGTNCARMGNAGYATHTTYTCNTGG------GTNACNTCNCAYGCNAGYGTNAAR GARGARAARYTNAARGAYAAYCCNAGYGTNGTNGAYGAYGAR---------ATGAGYGGN MGNAAYMGNAARGTNMGNGTNTGGGGNMGNYTNMGNCCNACNTCNAAYTTYTCNCAYGAR AAYGTNGARGTNYTNCCNGAYAAYAARGGNATHAAYATHCAYATGMGNMGNGAYCCNAAR AARGGNGTNGTNAAYAAYCARATHYTNGAYTGGTCNTTYAARYTNGAYGGNATHTTYAAY AAYGCNGAYCARGARGTNGTNTAYAAYACNGTNACNTCNGAYGTNGTNTCNAGYTCNYTN GAYGGNTAYAAYGGNACNYTNATGTGYTAYGGNCARACNGGNGCNGGNAARACNTTYACN ATGACNGGNGCNACNGARAGYTAYMGNCAYMGNGGNYTNATHCCNMGNGCNATHTCNCAR YTNTTYMGNCARATHGARGAYMGNYTNGARTAYGGNATHACNGTNMGNGTNTCNTAYATG GARATHTAYAAYGARCARATGTTYGAYYTNYTNGGNACNTTYCCNGARGCNCARTGGAAY AAY------AARGAYATHAAYTGYAGYCCNGAYCCNATGGTNATHTCNGARAAYCARGGN GGNGTNTTYGTNAARGGNYTNTCNTGYCAYYTNGCNCARAAYGARGARGARGCNYTNAAY YTNYTNTTYGARGGNGARACNAAYMGNTCNATHGCNGCNCAYTCNYTNAAYAARCARTCN TCNMGNTCNCAYTGYATHTTYACNATHTAYATHGARTCNMGNTCNMGNGTNCARTCNAAY GCNAARTAYACNGTNTCNAARYTNAAYTTYGTNGAYYTNGCNGGNTCNGARMGNYTNAGY AARACNAARTCNGARGGNAARACNAARGARGARGCNATGTAYATHAAYAARTCNYTNTCN TTYYTNGARCARGTNGTNATHGCNYTNGCNTCNAARTCNMGNGAYCAYGTNCCNTTYMGN CARTCNAARYTNACNCAYTTYYTNAARGAYTCNATHGGNGGNAAYTGYAAYACNGTNYTN ATHGCNAAYATGTGGGCNGARAARCCNCARYTNGARGARACNGTNTCNACNYTNMGNTTY GCNACNMGNATGATGTGYGTNGCNAGYGARCCNGCNGTNAAYGARATHTAYGAYCCNGCN YTNYTNGTNAARAARYTNCARAARGARATHTGYCAYYTNAARTCNGARYTNGCNATGCAY GAYACNYTNACNAAYMGNAGYATGATHTCNTAYGAYCCNYTNTCNGARCARCARAARTAY GARATHMGNACNCARGTNMGNMGNTTYYTNGARGGNAGYYTNGAYGARATHGAYATHGTN AAYYTNMGNCARATHGTNGGNTGYTTYGAYACNTTYAARGARYTNTAYCARGAYATGGAR AARGARATGGARTCNMGNYTNMGNGARAARTAYATGYTNATHGAYAARACNGAYCCNAAY TCNATHGCNGCNGCNCARCAR--------------------------------------- ------GCNGGNGTNCCNATHGCNGAYGAYGGNAGYTAYGTNGGNGAYYTNGARGGNGGN GGNTTYGGNATHGGNTCNGCNCCNAARAGYGCNMGNGGNGAYTCNTCNGCNGTNGTNCAR YTNAARAARAARGARMGNGARMGNGARMGNAARMGNGGNTCNMGNGGNGCNAAYAGYCCN ATHGCNGGNAARACNGCNTCNAGYCCNTCNCARAGYGTNAARGGNGARMGNAARGCNGAR TCNCCNCCNACNCCNGTNGGNGARMGNGTN---------GARAARGAYCAYGARGGNTCN GCNTCNCCNGTNAGYTCNACNGGNAAYYTNTCNMGNGCNGAYMGNAGYCARMGNCCNAGY ------------------------MGNCCNACNGARGAR---CCNGARAGYACNCCNCCN ACNMGNAGYGCNGCNTTYGARGARTTYAARAGYGAYMGNGGNAGYGARATHAAYMGNATH YTNATHGARAAYAARGARTAYYTNGCNAAYTCNAARMGNACNTAYTCNGAYYTNGCNAAR CARATGAAYAAYYTNAARATGAAYATHGAYACNTCNMGNCARMGNYTNGAYGARYTNAAR GARYTNMGNGARTCNGARGGNCCNATHYTNAAYGARGAYGGNGAYATHGTNATHAGYGAR GAYGARTTYAARGARATHACNAARYTNMGNGARYTNAARAAYTCNTAYMGNYTNAARMGN CAYGAYYTNGCNAARACNGARTCNGARGTNAARTAYTGYCARAARYTNGTNGAYCARTGY MGNYTNGARYTNATHCARGARTTYGAYAARTGGTAYAGYGARAGYTTYYTNAGYGCNTCN GARGARTAYCARACNAGYYTNGGNGTNGGNAGYGGNGTNMGNCCNGGNGTNATGYTNCCN ATHACNAGYYTNGCNAAYGARGAYGARCARGARAARTTYGARMGNYTNCARYTNGARYTN ATGATGAAYAAYCCNGARTCNGCNGCNTTYTAYAAYGCNCARATGMGNACNTCNMGNMGN AARATHTAYGGNGCNGCNATHAAYCARCCNCARCCNGCNTTYMGNMGNCARCCNGGNACN CCNACNATGAGYTTYMGNAAYCARCCNCCNGGNYTNATGCARGTNCARTAYATGTAYGCN CARATHGARCARYTNTAYGCNAAYYTNTGYMGNATHAAYTTYCCNCARMGNAARACNGCN GCNCARTTYYTNCCNYTNGAYGARGARATHTAYTCNGTNCCNTCNGAYGARYTNMGNATG GARAAYGARAAYYTNAARAARAARATHAGYGAYYTNGARGCNACNAAYGCNTCNAGYACN AARATGACNGARTCNYTNAARTTYACNTCNYTNGARGAYGARTCNACNTGYCCNYTNCAY CCNTCNAARMGN---GAYGTNAARCARATHTCNTCNACNTTYGARTGGATHATHTCNGAY TAYTCNGARAARYTNMGNYTNGARAARTGGGGNAARGTNACNAAYACNATHTCNGARCCN TTYTAYGTNGGNAAYGGNGGNTAYMGNGCNMGNYTNGARGTNTAYYTNAAYGGNAAYGGN AGYGGNTAYGAYAARTGYATGTCNATHTTYYTNMGNATHATHCARGGNCARTGYGAYGAY TAYYTNCCNTGGCCNGCNATHTTYTCNYTNACNTTYATHYTNGTNAAYCARGARGARMGN YTNACNGARTCNYTNGTNCAYGGNAAR---GAYGGNACNGTNTTYAARTAYTGYAARCCN TCNGGNGAYACNTAYGAYGAYAGYGAYTCNTGGGGNYTNATHGARTTYGTNCCNCAYGCN ATHATHAAYAARMGNAARTAYATHAARGAYGAYGCNATHAARYTNAARGTNAARATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MGNAAR------TTYCCNATGTAYATHGTNGAY GCNTTYACNAARMGNGCNYTNAGYGGNAAYCARGCNGCNATHTGYYTNGTNCCNCCNAAY ATHATHYTNCARGARGAYGARYTNCARAARATHGGNGCNGARATGAAYYTNTCNGARACN GCNTAYATHCARGTNYTNGAYAARGAYTCNGAYTTYAARTCNGGNAAYAARTTYTCNYTN MGNTGGTTYACNCCNACNACNGARGTNAAYYTNTGYGGNCAYGCNACNYTNGCNTCNGCN GCNGTNYTNATHGAYGGNGTNGGNAAYGCNAAYAARGTNATHGARTTYTCNACNAARAGY GGNACNYTNTCNGTNAGYMGNCAYCCNACNAARACNGGNTTYYTNACNATGGAYTTYCCN AARAAYGARCCNGCNCCNCARGTNACNGARAARYTNGARAARYTNYTNATHAGYYTNGTN GGNGAYYTNGAYYTNATHCARGAYGTNCARTAYTCNCCNACNACNAAR---AARYTNGCN GTNMGNTAYAARGAYCAYATHCAYMGNAARGARYTNGARMGNYTNAGYCCNAARCCNAGY ATHYTNATGGARGCNGARCCNTCNGGNATGGTNATGGGNGTNGGNGTNACNYTNAARGGN AGYCARATHAAYGGNTGYGTNGAYGARGARGGNATHGTNTAYGAYTTYGTNTCNMGNTAY TGGGCNCCNTGGAAYGGNATHCCNGARGAYCCNGTNACNGGNTCNTGGCAYACNGTNATH GGNCCNTAYTGGGCNAARGARYTNGAYAARAAYATGYTNTAYGCNMGNCARTGYTCNCAY MGNGGNGGNGAYYTNTGGGTNGARGTNATGGAYACNMGNGTNACNYTNATGGGNCARTCN GTNATHAAYYTNGARGGNACNTTYCARYTN---------------AARAARCARTCNAAR TCNTTYAARGTNYTNCARTGGATGACNGARACNGARAARGAYGARGARTCNGGNGARGAY GTNAARGARATGTCNGGN---------------CCNMGNAARCAYMGNGAYCCNGAYYTN MGNCAYAAYGCNGAYGAYGAYGARATGAARTTYAGYGGNYTNCAYGGNAARTCNGAYATH CCNTCNAARACNTTYGARMGNGTNAARAARTTYGCNCCNGARGAR--------------- ---AAYGGNCARGARACNCCNCARGAYGARGAYGAYACNGAYGGNGTNGGNAAYTAYAAY GARGCNTCNATHMGNTAYACNGGNAARAGYATHCCNTCNCCNGCNTTYMGNGTNYTNCAR ACNTGGGCNGARCAYGAYCCNGAYCAYTTYCCNAARGGNGGNCAYGAYGGNCARYTNCCN AARYTNATHGARAARTGYYTNAARAAYTTYCARACNGARAGYAARTAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GTNGGNAAYTTYMGNGAYGCNAARGAYCCNMGNCAR YTNGARGARAAYAAYATHACNCAYATHYTNTCNATHCAYGAYAAYGCNAARAARATHYTN AARGAYAARGARTAYYTNTGYATHGARGCNTCNGAYCAYTCNGAYCARGAYYTNTCNAAR TTYTTYCCNCARGTNAAYAARTTYATHCAYAARGCNMGNYTNGARGGNGGNGCNGTNYTN GTNCAYTGYYTNGCNGGNGTNTCNMGNAGYGTNACNGTNACNACNGCNTAYATHATGACN GTNACNGARYTNGGNTGG------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARTTYGGNAGYGTNGCNYTNCARGARAARYTNAAYATGGAYTCNTTYGCNAARYTNTAY GARTAYTAYTCNCARTAYAAYTTYCAYTTYGAYGAYCCNYTNGAYGARAAYYTNGGNATG MGNTCNYTNAGYTAYATGATHAARATGYTNCARAAYAAYGTNATGACNAARAARAGYAAR AAYGTNGARYTNYTNCAYAGYGCNGCNGARGTNACNMGNACNYTNAARGGNYTNMGNTTY ACNTTYTGYAARAGYGGNAARGAYMGNACN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TAYAARGAYCCNACNGGNGAR GARMGNATHTGGGARGGNGTNTCNMGNACNACNAARAAYACNGGNGARGCNGAYGCNGTN GGNATGGTNGCNGTNTTYCAYGAYCCNYTNTCNGAYYTNCARAGYGTNATHYTNATHMGN CARTAYMGNCCNCCNATGGARACNTAYACNATHGARTTYCCNGCNGGNYTNATHGAYAAR GGNGARACNGCNGAYACNGCNGCNGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GTNGARGARAARGAY ATHAARGARAARGARGARGARGARGARAARAARGTNGAYGTNGCNGAYGAYGAYACNGAR GAYATHGAYTTYGAYGAYYTNGAYGAYATHGAYMGNGTNYTNGARAARGCNYTNGARAAR AARMGNGARCARAAR---------------------------------ACNGAYATHAAR GARGARATHAAYGGNAARGCNGARGARATHCARGARACNCCNTGYGTNTCNTCNTCNGTN TCNTCNTCNGARACNAARAARACNGARAAYGARAGYYTNGARAAYYTNAARTAYGCNGTN AARGAYTCNGCNGARYTNGCNYTNCAYAARYTNCARTTYYTNGAYATHTCNACNAARAAY YTNTCNAARYTNCARGTNYTNYTNGTNGARYTNCARACNMGNTAYAAYGAYTGGCARTCN GGNGGNYTNTCNACNYTNTAYTTYCAYAARCARYTNAARTGYTCNGARGCNYTNYTNTCN CARTAYGARGARAGYGCNGTNCCNACNGGNTGGTCNTGYMGNTGGGAYMGNGCNAGYTGY MGNTAYTTYTAYMGNAAYGARCAYAGYGGNCAYACNCARTGGGARTAYCCNCARGTNAAR GTNAARGGNGGNGARGTNAARGAYTCNAAYAGYAGYMGNGGNMGNGGNAGYAARAARMGN MGNAGYAARGAYGTNGARGARMGNGARAARGARMGNGARMGNGARGAYAGYAGYAARTCN MGNMGNAGYAAYMGNAGYCAYMGNAGYAGYAARAARGAYMGNGGNAARMGNGARMGNCAY AGY---AGYTCNCAYCAYCAYMGNAARAARAARMGNMGNMGNMGNGAYCAYAGYAGYAGY AGY---AGYAGYAGYGARGAYGARAAYAGYCAYTCNCAYCAYMGNCAYAARAGYAARMGN AARAARAARGGNMGNTCNGAYAARTCNCCNAGY--------------------------- YTNGARYTNGTNGAYTAYGARGGNCCNGARCARCAYGCNCARATHATHGARGAYAGYCCN CCNCCN---------------------------TCNATGTCNCARYTNGAYTCNGGNGAR GAYAARGTNGGNATHGAYGCNAGYGGNGARGGNGGNGAYCCNGGNTCNYTNCARTCNCAY TCNACNYTNGGNYTNATHGCNGAYTAYGGNTCNGAYCARGAYGTNGARGARGARGARYTN GARGGNGARGARGARGARGGNGAYGARGARGTNAARGARGARGARGARGARGARACNGTN ---AAYAGYGCNGTNATHGTNAARCCNCCNCARATHATHGTNCCNCCNTAYGTNGCNGCN ATGAAYCARCCNCARATGTAYTCNACNCCNGCNYTNTAYCAYTCNACNACNACNACNACN ACNTCNGGNCARATGGARCCNACNGAYCAYGARCCNGARCARGGNGARGCNGARGCNGAR AARGCNGCNAARAARAARAARAARGARAARTAYGGNAARGARAARTCNYTNAGYGCNAAY TCNAGYATHATGATGAARAARAARMGNGTNTCNTCNATGGTNCARAARTGGCARCARGTN AARAARGARGTNGARAARGARAAYMGNGAYAARGARYTNMGNCARGCNGCNATHMGNGAR AARATHAAYCARYTNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GGNACNMGNTTYYTNAARMGNGGNACNAAYYTNGAR GGNTAYGTNGCNAAYGARATHGARACNGARCARATHGTNCARGAYACNGCNGTNACNTGY YTNGAYMGNGGNAARGTNTCNTCNTTYGTNCARCAYMGNGGNTCNGTNCCNYTNTTYTGG TCNCARGAYATHTCNAARATGGTNCCNAARCCNCCNATHTCNYTNGAYCARMGNGAYCCN TAYTGYAGYGCNGCNGGNATGCAYTTYAAYGARATGYTNCAYMGNTAYGGNTCNCCNATH ATHGTNTTYAAYYTNGTNAARACNMGNGARAARAARMGNCAYGARAGYATHYTNAGYGAY GAYTAYGTNCAYACNATHGAYTAYYTNAAYCARTTYYTNCCNGCNGARCAYAARATGCAR TAYATHGGNTTYGAYATGGCNMGNGTNAAYAARMGNAARGAYGCNGAYGTNATGYTNMGN YTNAAYMGNATHGCNMGNTAYTGYYTNAARCARACNGGNTTYTTYYTNMGNGTNCARCCN CCNCARGCNCARTAYYTNATGAARGAYAGYGARYTNGARTGYYTNAARGGNATHTGGGGN CCNAAYGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GTNCCNGGNCCNCCNYTNCCNCCNYTNATHACNAGYACN AGYGTNTCNGARGARATHCCNGCNACNCCNCCNYTNGTNCCNTCNATGGTNAAYATGCCN AGYATGATGGGNCCNACNATGCCNTCNYTNCAYGAYMGNTTYATGATHMGNTCNATGATG YTNCARCARCARCARCARYTNCARCARCCNYTNCAYCCNACNCARCCNATHATGAGYACN GCNGTNCCNACNCCNATHCCNTCNGCNACNCCNAAYCCNGTNAGYGARCARGARGCNCCN YTNTGGGCNAAYAGYTCNCARCAYATGAGYATHTGGTCNCARCCNTCNCCNATGTGGAAY ATGGAYGCNATGAAYGAR---AARTCNCARGCNTAYAARATHCAYYTNGARAAYATGAAR MGNGARMGNGARGARGARAARYTNAAR---GARGARMGNATHAARCARGARYTNATGGAR AGYAARCARGARGARYTNMGNAAYCARCARAAYGARYTNYTNMGNCARMGNGARCARATG AARMGNGARAARGARGARYTNGARAARGARMGNYTNMGNAARYTNGARGARGTNMGNMGN GARGARGARMGNATHGCNCARYTNGARAAYGTNMGNCARAARAARGARCARATGGARCAR CAYATGAARATGCARGARGARAARAARMGNCAYGAR------------------------ ---------------GARGARAARAARAARMGNGAYCARGAYATHAARAARCARGARGAR AARAARMGNAARGARGARGARAARYTNAARGARCARAARMGNAARGARGARGCNMGNMGN GCNAARGAR---------------YTNGARGAYATGMGNMGNCARCARGARAARGARMGN CARMGNGARGARATGCARMGNCARYTNGARYTNCARCARATHYTNGARGARGARGARMGN ATHAAR---------MGNGARAAYGARGARAARGAYAARCARCARCARGCNATHAARAAR CARYTNGARYTNCARAARCAYCARGARTCNYTNMGNAARYTNCARCAYGCNCARAARGAR CARYTNGCNAAYATGCARYTNCCNGCNTCNAGYAAYTGGGCNAARCAY---GCNCCNCAR GGNAGYGTNGGNCAYTCNAARTCNYTNACNGARATHCARGARGARGARGCNMGNMGNGAR AARGARMGNCARAARGARCARCARGCNYTNAARCARAARGTNCARGARCARGCNGCNATH YTNCARCARCARCARAAYCARAARTCNTGGGCNTCNCARGTNTCNAARGGNATHTCNMGN GGNCCNTCNYTNYTNGAYATHCARCARCARGARAARGARAAYGCNAARAARGCNGARAAR GARMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TAYACN GARGCNYTNGCNYTNGARAAYACNMGNGAYGAYATHTAYTGYTTYMGNGCNCARGCNAAR YTNTCNYTNGGNAARTCNTCNAGYGCNATHAARGAYTAYGAYGARGCNATHAARYTNAAY AARAAYAAYCARAARGCNTAYATHAARAARGGNTCNATHYTNTTYAARATGGGNGARGTN YTNCARGCNCARTGYGTNTTYCARGARGGNCARAARCAYTGY---GGNGAYAARGARTTY GARGAYTGGYTNGGNAARGTNGARTCNMGNYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNATGCCNAARMGNAARTCNGARAGYGCNCCNGCN--------------------- ------GCNCCNGCNGCNTCNCCNAARAAR------------------ACNAARTCNGAY TCNGARAARMGNGGNMGNGGNMGNCCNCCNYTNTCNGCNGARGARAARGCNAARMGN--- ---GCNAGYAARCCNGCNTCNGGNMGNGGNMGNGGNMGNCCNAARGGNAGYACNAARGCN GCNAARAARAGYAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNCCNYTNTCNAAYYTNCARYTNGARTGYCAYATHTAYAAYCAR CARGAYAARYTNAARAARYTNTGYGAYGARAAYAAYATHGTNGTNTCNGCNTAYTCNCCN YTNGGNTCNCCNGAYMGNCCNAGYAARCAYGGNAARGARGCNYTNTCNGTNYTNAARGAY TCNGCNATHYTNGARATHTCNGARMGNTAYAARAARACNCCNGCNCARGTNYTNYTNAAY TTYYTNYTNAARMGNMGNATGGTNGTNYTNCCNAARAGYTCNAARAARGARMGNATHAAR GARAAYYTNCAYTGYYTNGARTGGTTYYTNAGYGAYGCNGAYTTYAARACNATHAARAGY YTNGAYMGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TCNACNTGYCCNACNATGTCNYTN TTYYTNCCNCAYCARTGYCCNGARCCNYTNGCNAARAAYAGYGCNTCNGTNTCNATHGGN AGYMGNATHTTYGAYMGNCARATHMGNCCNCCNCAYGGNGGNCCNAAYGGNYTNMGNTTY ACNMGNMGNTAYYTNTAYTCNAARATHTGYYTNYTNACNAAYTAYMGNGAYACNTCNGGN GAYGGNYTNGCNTGYTGYGCNTTYGAYTGYGGNGGNGAYTCNATGTTYATHGGNTCNTTY GCNGGNGARYTNMGNGCNGTNCCNGTNAGYGCNACNAGYGAYGAYTAYGTNAGYACNATH TGYCAYTCNTCNCCNGTNATHCARATHAAYACNTCNATGGTNGAYCCNGAYYTNATHATH ACNAGYACNTGGGGNGCNTCNCARAAYAGYGCNYTNTGGGGNTTYAARMGNGAYACNGAY ACNTGYGTNYTNAARTAYMGNTTYGAYGARCAYCAYGCNACNYTNGCNAAYYTNAGYCAY GAYMGNTTYATHGGNACNAARGAYTTYGTNGCNACNATHTAYGAYACNGCNGCNGGNACN AARGTNCARACNYTNTAYGAYGARAGYAARGCNAAYAAYTAYAARTTYAAYGTNGCNTCN TTYAAYCCNACNGAYGAYYTNGTNYTNAAYGAYGGNAAYYTNTGGGAYGTNMGNTCNAAY AARYTNATHTAYAARTTYGAYAARTTYAAYCARTAYACNAGYGGNTGYTTYCAYCCNGGN GGNYTNGARGTNGTNATHAAYTCNGARATHTGGGAYATHMGNACNTTYMGNYTNYTNCAY ACNGTNCCNGARYTNGAYCARTGYCARATHYTNTTYAAYCAYGGNGGNGAYGTNATHTAY GCNATHMGNGTNGAYGAYGAYYTNTCNGGNGAYYTNYTNATGMGNMGNGAYTAYGCNTCN ACNYTNAARACNTTYGAYGCNTTYAAYTAYTCNGGNATHGGNACNTTYGAYYTNAARACN AAYAGYATHYTNGAYYTNGCNGTNGAYMGNAAYGAYCARYTNATHGGNGTNATHGARAAY ATGTCNCARCAYGARTCNGAYCCNGARGARTCNATHTGYMGNGTNTAYGARATGGGNAAR YTNMGNATGCCNGARGAYACNCCNGARGAYGARGARGAYGAYGGNCARAAY------GAY AAYTAYGAYGAYGAYGAYGAYGAYGAYGGNGARAAYGAYTTYGTNAAYGTNGTNGARTTY TCNGARACNGCNAARTTYGTNAGYAARTGYTTYAAYCAYACNGCNTTYGTNCARGCNAAY TTYMGNAAYAARAARCARYTNGARAARGAYGTNGAYAARYTNGARGCNYTNGGNCARGCN GAYTTYAGYGTNGCNATHAARTTY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNTTYGTNTTYGARACNAARTCNCCNTCN CCNACNAARACNAARGCNYTNAAYYTNAARAARAARGCNACNYTNATHTGYCARAARAGY CCNGTNAARATHYTNCCNMGNCCNGAYAAYGTNTCNATHAAYGAYGTNGGNATHAARACN AARAGYMGNTCNACNATGYTNACNMGNTCNCARMGNGGN------------ATHTCNAAR CCNAARMGNAARGARGARCCNAGYCAYAARGCNGTNAAR--------------------- ---MGNGTNAARAARACNGARGARGARTAYGARAGYTCNAARGARACNGARAGYGARGCN AGYGARATHGARGARTCNGGNYTNTCNCARGARGARGAYGAY------GAYMGNACNAAR YTNGAYGAYYTNATGGCNGCNAGYACNACNATHMGNTTYGGNTCNAARCAR---CCNTCN ATHGAYGARGAYATHAARTCNAARGCNGCNMGNMGNAARGCNYTNTCNYTNTCNYTNYTN CARCCNGAYYTNGTNCARAAYGAYCCNAARAARGAYGAYMGNGAYACNGCNTTYGCNCAR CARTAYTTYAAYCARGTNAARGARACNYTNTCNTCNGAYCCNGAYMGNTTYTAYAARTTY YTNTCNYTNYTNAARGAYYTNAAYAARGAYCAYACNAGYCCNGTNGARYTNTAYYTNGAY ATGGTNATGYTNYTNTCNGAYCAYCARCARYTNGTNGARGAYTTYGCNGGNTTYYTNYTN TCNTTYCARGCNGTNGARTGYCARTGYTTYTCNACNAGYTAYCARTAYAAYCARATHMGN CARTTYYTNMGNCARGTNGARGTNCAYTGYGGNTCNTCNACNGGN---ACNTAYMGNAAR GTNYTNAARGCNYTNTCNACNTGGAGYAGYATGTGYCARGARGGNAARYTNAARGGNAGY YTNMGNGAYAARATGYTNACNATHYTNMGNAGYGTNCCNGGNGTNYTNGAYAAYYTNATH AGYTAYTTYYTNGAYGGNGCNGTNGGNAARTGYCAYGCNATGGAYTTYGARGAYATHTGY YTNGAYGARAARGGNGARGARATHAAYGAYGGNGAYGARTTYGARAAYATHGTNYTNCCN GAYACNCCNGARGAYTAYAAYACNAARACNTGYACNTGYCAYTGYCAYAARAAYAAYACN CARGAYGARAARTAYYTNMGNMGNGCNAARCAYTGYGTNTCNTGYAGYYTNCARATHTTY GARGGNCARCCNGTNYTNAARATGTCNMGNTAYGAYTAYMGNCCNGTNTCNATHGTNTAY CCN---------TCNGARGARATHGARAARYTNTCNAARGCNAARATHGARGCNGCNCAY ATHGCNYTNGCNAARGCNAARATHCARCARCARCARATHGGNAARAARMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATHATHCARTGY YTNTCNGCNYTNCCNGARCCNAARGTNACNGAYGTNGAYGCNMGNAGYGCNAARGTNAAR YTNTCNCCNCCNGAYTGYGGNGAR---ATGGARATHTAYCCNTCNGAYYTNAARTAYGAR YTNTTYYTNTCNGAYAGYGGNMGNGAYAARAARTAYGAYTCNGTNTTY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TCNAAR GARGAYMGNATGAARGAYMGNYTNATHMGNTGYGCNCARTGYCAYAARATHGGNCAYATG AGYTGYYTNGAYYTNACNGARGAYYTNGTNGCNGTNATHAARACNTAYCCNTGGCARTGY ATGGARTGYAARACNTGYGTNCARTGYATGGAYCCNTAYGAYGARGAYAARATGATGTTY TGYGAYMGNTGYGAYMGNGGNTAYCAYACNTTYTGYATHGGNYTNGAYGCNYTNCCNACN GGNCAYTGGGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---TCNCARATHATGGGNYTNCCNGAYATHYTNGGNACNGCNGAYGGNTGGCCNTAYYTN TTYGTNYTNAGYGCNATHCCNTCNYTNATHTGYYTNCARTCNYTNMGNGARACNGTNGAY YTNAGYGTNCAYGGNGTNGGNTTYATHTCNGCNGAYGARGTNAARGARGAYCAYTGGATG TCNCARGCNAARGTNATHTGYTTYGGNGGNGGNTAYGAYYTNGGNTTYATHGARTCNYTN GGNCCNTCNGGNATGCARAAYATHMGNAARTTYGTNAGYGGNGGNGGNTCNTAYYTNGGN ATHTGYGCNGGNGCNTAYTTYGCNTGYGAYTCNATHGARTTYGAYATGAAYGGNCCNYTN GARGTNGTNGGNAARMGNAGYYTNAARTTYTAYACNGGNAARTGYATHGGNCCNGCNTTY CARGGNTTYGAYTAYAAYTCNMGNMGNGGNGTNCAYGCNGTNCCNGTNATHTAYCARAAY ATGGARGTNCARACNTAYYTNGARGGNGGNGGNTAYTTYATGCCNGARTGYCARTCNTCN CARACNCAYACNACNGARGTNYTNGGNCARTAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATGGCNAARMGNGGNCCNCARTCNGARYTNAAYGAYMGNAAYTGGGAYGAYGAR GARGARGTNGARGARGCNGGNGTNTTYAARCARGCNACNAARGAYGCNATGCARAGYMGN GTNATHAARAARGCNAARMGNMGNGTNGGNGGNGARGARGGNGGNGCNAARACNGCNTTY GGNGGNTTYGGNGGNYTNGTNAARAARGGNAARATHTCNACNGARAAYAAYAAYYTNGGN ATGMGNTTYGGNACNGGNGAYTCNAGYGGNTTYTCNAGYACNGGN---GGNGCNGCNACN TCNTTYAAYATHGARTCNACNGCNTGYAARAGYGAYTCNTCNTCNTCNAARGAYAAYTCN ACNTAYYTNCAYGCNYTNAARTCNYTNAAYGARAGYGTNYTNGCNTGGATHAARCARCAY GTNGAYAARAAYCCNTAYATHATHYTNACNCCNATHTTYAARGAYTAYGARAARTAYYTN GCNAGYYTNGARGCNAARAAR------ACNCCNGCNACNAAYGGNTCNGAYTCNACNTCN GGNATHAARAAYAAYGGNAGYAAYATHAARACNTCNACNTTYTCNCCNYTNAARAARTCN GCNGAYGARTCNGAYTCNAGYAARGAYGGNAARAARGARAARGAYGAYAAYAAYGARTCN ACNTCNAARACNTTYACNTTYGGN---TCNGCNTCNGCNGCNAAYGGNGAYGGNTTYAAR TTYTCNACNGCNAARACNACNACNACNAAYTCNGGNTTYTCNTTY---------GGNAAR ACNTCNATHTCNTCNGGNTTYTCNTTYTCNATHTCNACNGCNACNACNGCNAGYTCNACN ACNCCNGCNACNACNGGNTTYTCNTTYGGNAAYAGY------------GGNGGNACNTCN ------------------TCNTCNGGNTTYTCNTTYGGNACNYTNGCNGCNGCNAARACN GCNTCNGAYCARGCNGGNAAY---------TCNAARGARGGNGGNGARGAYGAYGAYTAY GTNCCNCCNAARCCNGARGTNAARGARATHAARGARGAYGGNTCNYTNTAYTCNAARMGN TGYAARYTNTTYTAYCARAARGAYGGNAGYTGGGTNGARMGNGGNGTNGGNAAYGTNCAY ATHAARCCNYTNGAYGARCCNAARACNCARYTNYTNTTYMGNGCNGAYACNAAYYTNGGN AAYATHYTNYTNAAYATHAAYYTNACNTCNGCNYTNCCNACNTCNMGNCARGGNAARAAY AAYGTNYTNYTNGTNTGYGTNCCNAAYCCNCCNYTN------------AARGARGGNTCN ACNGAYCARACNCCNATHCCNATGYTNATHMGNGTNAARACNGCNGARGARGCNGAYGAR YTNYTNGCNAARYTNGARGARMGNAARGCNYTNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GGNACN GAYGTNYTNGTNACNGGNCAYTCNYTNGGNGGNGGNGTNGCNGCNYTNYTNGCNGCNYTN TGGMGNGAYGCNGCNGCNAGYATGMGNTGYGTNACNTTYGGNTGYCCNCARGTNYTNGAY TCNAGYCAYGCNYTNGCNYTNTCN---AAYTTYACNACNAGYGTNGTNYTNGGNGAYGAY YTNGTNCCNMGNYTNAGYYTNACNACNGTNCARGAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CCNATHAARGTNACNAAYAARATHCCNTCNCCNTTYACNCCNATGGCNCCNTAYGAYGAY ATGAAYACNCCNGARYTNAARAARGCNGTNGGNCARGTNGGNGTNMGNCCNATGGGNAAR AARMGNATGMGNGAYYTNYTNAARCAYATHTAYGTNGARACNCAYCARTAYGARACNGAY ACNGAYGAYGCNGAYACNCCNGTNAARMGNCCNAAYCARAAYGCNGARTTYACNGARYTN TCNYTNTTYACNAARATHTCNGARMGNAARMGNGGNCARATGTCNGGNAGYAAYAGYAAY AGYTCNGARATHTCNGGNGAYGAYTCNGAYTTYAARAARMGNAARCCNYTNATGAARGAR AARGAYTTYTCNAAYCCNTCNYTNGCNAAYGAYAARGARGGNCARGGNGTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARGARGAYGAYGTNYTNAGYTCNYTNGAYTCNAGYTTYAGYGAY GGNCCNGAYYTNCCNGARGARAGYATHYTNCARGTNYTNCCNGAYGARGAY------GAY ATGGAYGTNACNCARYTNACNCARACNAGYATGGARGCNYTNAGYGAYMGNYTNATGAAY TTYYTNAARGAYGAYMGNGARATHTAYGARAARATHYTNATGTAYGARGCNYTNGARYTN GAYGTNYTNAARAARAARATHTCNGAYGCNGGNATHMGNATHGGNATHTCNMGNYTNCAR GAYTTYYTNGAYGARMGNTGYATHACNTTYTCNATGAARAAYATGAGYAAYMGNAAYAAY MGNAAYCARCCNMGNAAR------AARAARAARGGNAAYTCNCCNCARAARMGNACNTCN ACNATHAAYATGAARGCNTGYGCNGTNGCNATGGGNGGNAARYTNGAYGGNTGGYTNGAY ACNYTNAARGARAAYATHYTNGGNGARYTNAARGGNTCNYTNATGTCNTCNYTNMGNTCN CARCAYGARGAYCAYAARAARTCNGTNAARGGNYTNCARGCNGARAARGTNGCNYTNCAR AARGARGTNAAYMGNYTNAAYGARCARATGAAYGGNYTNGARCAYAGYTTYCARCARAAR TGYACNYTNATHAARAAYYTNACNGAYTCNYTNGTNGCNCARAARAARAARGTNGAYATG GCNAARCAYTTYTAYCAYTGGAARGCNGAYCAYTAYGAYAARCARMGNGARATHTTYACN GARAARYTNGCNGCNCARCAYCAYGARMGNAARYTNAAYYTNMGNGTNYTNAARGCNTGG TAYGGNGTNATHCARACNMGNTGGMGNTCNMGNACNGARMGNAARAGYCARACNCARGCN AARGARATGTGYYTNAAYYTNACNAGYGAYTAYGARACNAARGTNTGYATGYTNAAYGAR AARATHTCNGCNYTNGARAARAARGTNTCNYTNYTNCARGCNGARMGNGARATGTAYTCN GARCARGTNMGNAARGCNTTYATGMGNGGNATGTGYGCNYTNAAYATGGARACNATGTCN GTNTTYGGNGARGAYCARCARAARCARACNYTNGTNGARGARTCNCCNATHGARGTNTCN ACNTTYGAYACNAAYACNYTNGCNACNAGYATGGARGAYGTNCAYAGYAAR--------- ------TCNTAYCARGGNACNGARGARAAY---------------TTYATGAGYAAYAAY TCNCAYCAYTCNCAYACNTCNTGYTCN------------------------CCNACNMGN ACNGGNGGN------TCNAARCARCCNGARGTNATHCARMGN------------------ CCNGTNTCNYTNGCNGCNACNTGYTCNTCNAARACNAARGTNACNAARTCNMGNCCNAAR TCNGCNAARGCNCARGGNAAYAGYYTNGCNCCNCCNATGGCNTCNGTNATHGTNGARMGN CAYCCNCCNGTNAAYAARCARACNATGGGNAARGCNACNGCNGTNMGNTAYCCNAAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GCNGGNCARGCNCAYCCNGTNGCNYTNCAYATGGCNGGNGARGTNCCNMGNGTN ATHGCNACNTCNTCNACNTCNTCNACNCCNCARTCNACNGCNACN------AARAARCCN GGNYTNAARGTNGTNATHCCNGAYMGNGCNCCNGCNGTNGCNCARGCNAARGTNCAR--- GGNACNGCNYTNGAYACNCCNAGYGTNTCNATHGCNACNCCNAAY---AGYCARAAYGCN CARGGNGCNATHCARGCNATHYTNCARTCNGGNGAYYTNYTNAAYAGYGCNGAYATHGCN GGNYTNTCNCCNYTNGTNTAYCARYTNACNAAYCARGGNTCNGGNCCNGGNCCNYTNACN GCNGCNYTNCARGCNTCNGGNGTNTTYACNCCNGGNGGNTCNYTNTCNATGTCNACNACN CCN---------YTNATHACNYTNCCNGCNCARAARTCNGARYTNGTNAARCARGARCCN CCNGGNTCNCCNAGYMGNCAYGARCAYGTNGCNGARGGNTCNTCNGTNACNCCNCCNCCN GCNTCNAAYCARGGNGARCCNCCNGARAARMGNCARMGNTTYGAYACNGAYATGAGYTCN GAYATHTGYTTYAARTGYGGNGGNMGNGGNCAYTTYGCNMGNTAYTGYGGNACNGGN--- ------------------------------GGNGGNCCNCARMGNGGNTTYCARGGNGGN TTYTCNGGNCARAARTGYTAYAARTGYAAYMGNACNGGNCAYTTYGCNMGNGARTGYACN CARGAYCARGARMGNTGYTAYAARTGYAAYGGNYTNGGNCAYATHGCNAARGAYTGYGAR AARCARATHTCN---ACNGGNGCNTGYTAYAAYTGYGGNAGYAGYGARCAYYTNCARMGN GAYTGYCCNCARGCNATHGTNAARTCNTGYTAYMGNTGYAAYGARTCNGGNCAYYTNGCN AARGARTGYCCNGCNGAYATHCCNGGNAARCCNTTYGCN------------GAYGAYMGN AARTGYTAYACNTGYGGNGGNATHGGNCAYYTNGCNAARGAYTGYCCN------------ TCNCCNMGNAARGARTGYTAYMGNNNNNNNNNNNNNGGNCAYYTNCARAARGAYTGYCCN AAYGGNCCNCARTCNGTNACNCARTGYTAYAAYTGYAAYGARGTNGGNCAYATHGCNMGN GAYTGYACNGCNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATHGGNATGAARAAYGGNATHATH TAYCCNGARCARACNGARMGNCCNATHAARTAYACNMGNAARCARATHGAYTGYTCNATH YTNGAYGAYATHGGNCAYGGNGTNMGNTCNCARAGYCARCARGCNACNACNCCNMGNCCN GGNMGNTCNCCNTCNGTNAGYAGYACNCAYAGYAAYATHAGYAGYAAYCAYCARCARGCN CCNACNTCNAARCCNCCNACNCCNCCNGTNGGNACNGGNCARGGNAGYGGNACNATHGGN MGNGCNGGNGGNGGNCAYTAYMGNGCNYTNGGNCCNCCNGTNGCNCCNCCNGTNGCNCCN CARCARATHTCNACN---------CCNCCNCAYTTYCAR---ATHYTNGCNTCNCCNCCN YTNCCNCCNCCNCCNTCNTCNGARYTNCCNGAYCARTTYGAYTAYCCNGCNCCNCCNCCN CCNCCNGAYTTYAGYGAYGARMGNGARGGNCCNCCNAGYATGMGNGGNGAYGTNCCNCAR CCNYTNGARAAYGAYATHTAYGGNACNGGNGGNGGNGCNGGNGAYGAYCCNTAYGCNGCN ACNGGNCCNCARTTYYTNGCNCARACNTCNTGGATHCCNAARCAYTAYYTNGARAARGTN GTNGCNATHTAYGAYTAYCARGCNAAYAARGGNGAYGARYTNTCNTTYGCNGARAAYGCN ATHATHTAYGTNATHCAYAARAAYGAYGAYGGNTGGTGGGARGGNGTNATGGAYGGNAAR ACNGGNYTNTTYCCNTAYAAYTAYGTNGARCCNTGYATG---MGNTAYYTNATHATHACN GCNGAYGAYTTYGGNTTYAGYAARGARMGNAAYGARGGNGTNATHGAYGTNGCNAARATH TCNGCNGTNACNAGYGCNTCNYTNYTNYTNAAYTGYACNGGNACNGAYGAYGCNATHCAR YTNTTYGARAAYCAYAARYTNTGYTCNGGNYTNCAYYTNAAYYTNACNGARGGNCAYACN YTNAGYAARAARGCNTAYTCNACNYTNACNGAYTCNGGNGGNGARTTYTGGGGNAARTTY GARYTNMGNAARMGNYTNGARAGYGGNAARATHGAYCCNYTNGARATHAARYTNGARATH CARTGYCARATHGAYGTNTTYAARGARGTNATGGGNAARCAYCCNYTNTAYGTNGAYGGN CAYCARCAYATHCAYGTNCAYCCNGCNGTNGCNGCNATHTTYTCNCARACNYTNAARACN AAYGGNATHCARGTNACNMGNYTNCCNATHGARYTNTCNATGGAYCARAARCARTGGGTN AARCCNTCNGTNATHCCNTTYTAYAAYAARATGATGACNGAYGCNGARAAYAGYAARTCN ATHTTYGAYAAYTGYGGNATHMGNTAYACNGAYGCNTTYGTNGGNYTNTCNACNATGGGN AGYGAYATGACNGCNACNMGNYTNCARTCNAGYATHYTNGARGGNTTYCARGAYGCNGAR ACNMGNTGYGAYAAYTCNACNAARACNTTYGTNACNTGYGARYTNATGTGYCAYCCNGGN TAYGCNACNGGNAARCAYTCNGGNGGNTTYGAYGGNTGYTCNGAYGARTTYGGNTGYTCN AARGAYMGNGARCAYGARATHACNGTNYTNTCNTCNAARGARATGTTYGARTTYTAYGAR AARAAYAAYATHCAYYTNGTNTCNCAYGARATHYTNGTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNYTNATHTAYGAYTTYTGYGTNTAYGAR TGYCARCARGGNAAR---AARCARYTNACNTCNAGYAARGGNGTNMGNCCNAAYCARMGN ACNYTNAARTTYAAYTAYCCNGCNTAYTTYGGNATHGCNGCNGTNGAYATHAAYGGN--- ------------GTNACNGGNGCNAAYCAYCAYCAYGARAAYCAYCCNTGYGAYAARYTN CCNTCNTCNYTNTAYCCNGARAAYMGNYTNCCNYTNGTNAAYGARACNGTNAARGCNATG GCNAARACNAARGTNTCNACNACNCARYTNMGNCARTAYATH------------------ ---------------------------------------------AGYYTNGCNGTNMGN MGNYTNMGNCCNTTYGCN---YTNGGNYTNTAYACNAARACNGGNAARTCNGTNCAYACN ACNTCNMGNAARTAYGGNGARGCNYTNTAYMGNGARAARATG------TTYGARTAYCAR GARCCNAARTAYATHCAYCAYTCNGGNACNGCNYTNAGYGCNTTYATGTGGTAYTGGATH YTNTAYCAYTGYTAYTTYGARTAYGARCAYYTNGTN------------------------ ---------------------ATGCCNGGNGARGARCARGTNGTNTTYYTNAAYAARYTN GGNGARATHCCNGTNYTNAAYGAYGGNTGGTAYGCNGCNACNGAYTAYTAYTCNAARGTN MGNGAYTAYAAYGCNYTNATGMGNATGACNTTYTCNATGGCNGARTCNAGYGTNAARGTN GCNGGNCARYTNTCNACNCCNGTNYTNAAYCAYTAYCARCCNCARATHAAYAAYYTNAAY GAYTTYGCNTGYAARACNYTNGAYAAYYTNGARAAYAARTAYCCNGCNATHAARCARCCN ACNGARCARTGGAARGARACNTGYGCNGAYTTYGTNGARCCNGTNGTNGGNMGNGTNAAR CCNATGATHTCNCARGTNCARGGNATHGTNGAYAAYGGNAARCARMGNATHAAYAAYATH AARACNGCNGGNACNAAYATGGTNGARGGNGTNAARAAYMGNGGNGTNGAYACNGTNGCN CAYGTNGTNAAYACNACNTTYGAYACNACNCCNGGNMGNTTYGTNACNMGNACNGTNGAY AGYGCNYTNGAYATGGCNGAYAAYYTNGTNGAYAARTAYYTNCCNGARGARAARGAR--- ------GARAARGARGGNCARGARACNGTNGARGARAARMGNGGNGARGARTCNGCNYTN AGYTCNGGNATGGGNGTNGARAARATGGARGARATGGAYCCNTCNCCNAARMGNGTNYTN GTNCAYGCNGGNAAYGTNACNGAYAARATHMGNAARMGNATGTAYMGNMGNGCNATGAAR GAYATHACNTAYGCNMGNGCNMGNACNTCNACNGCNYTNAARMGNATGACNAAYACNGTN GARYTNATGGAYCARGCNAARAARAAYYTNAAYACNGCNAARGARAARGTNGAYCAYATG TGGTCNGARATGGTNAARGAYACNGAYGTNGARGAYGARMGN------------ACNGTN TTYGCNGGNAGYGTNGARGAYMGNATHGTNGCNYTNGGNMGNATHGTNGCNMGNCARYTN AARTCNGGNGTNACNTCNYTNGARAARGCNTAYTCNGARYTNGGNGARTTYAGYMGNAAY CCNATHTCNAARTCNAARGAYTAYAARGARYTNATGTCNACNTTYYTNTCNGTNGARTCN YTNMGNAAYYTNTCNTCNCARAAYYTNCARMGNGCNMGNGARTCNYTNAARTAYYTNCAR GAYMGNGTNAARAGYYTNTTYAAYAAYGCNCCNAGYYTNAGYTGGGTNGCNGTNGAYATH AAYATGGARAAYATHCCNATHAAYGARAAYGAYYTN------------------------ ---CARGTNTTYYTNYTNAARCARAAYTGGAARGGNGTNATGMGNAAY---GAYGAYTTY GGNATHGAYTTYCAYYTNMGNYTNTTYAARACNAAYGARGGNYTNCARGCNATGTTYCAR AARTTYAARCAYATHCARTCNGAYGAYGARYTNMGNTCNAAYGARGCNYTNGARTAYCAY GCNACNATGGTNATG--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNATGTGGTAYCAYATGGARMGNACNCARGAR ACNTAYMGNYTNTCNGAYCARYTNATHMGNGCNATHGGNAARGGNAARYTNCAYGAYMGN GARGARGAYATHAAYTCNYTNATHGARAARGGNGCNGAYATHAAYMGNMGNCAYGGNACN YTNYTNCCNYTNCARTAYGCNTGYTGYYTNGGNGAYTGGCAYGTNYTNGARYTNYTNATH CARMGNGGNGCNAARGTNAAYGARCCNGAYGGNTAYAAYMGNACNGCNYTNCAYTAYGCN GCNGARCARGAYGARMGNTGYGTNMGNATHYTNYTNGARAAYGGNGCNYTNCCNGAYATH GGNGAYGGNAAYGGNGAYACNGCNYTNCAYTGGGCNGCNTAYAARAAYAAYACNYTNTGY GTNCARMGNYTNYTNCARCAYMGNGCNAAYGTNAAYGCNGTNGAYYTNAAYAAYGAYACN CCNATHAGYTGGGCNGCNMGNAARGGNAAYYTNGAYGTNATHCARGTNYTNYTNAAYTAY AAYGCNGAYGTNGAYATHMGNAAYGTNTAYGGNCARACNGCNYTNAARAARTCNGCNGCN GTNCARGCNAGYGGNYTNAAYAAYGARGCNGAYGAYGCNTGYYTNGARYTNYTNATHAAR GCNTCNGGNCARTTYGAYYTNACNAAYYTNAARGGNGARYTNYTNCCNGTNATGGCNMGN GAYAAYMGNYTNAAYGARATHYTNTAYCCNYTNGTNAAYTCNCCNMGNTCNYTNYTNGAR CARTGYMGNMGNMGNATHMGNCAYAGYATHGGNCARAAYTAYYTNCCNGAYGTNATHTCN GARYTNCCNYTNCCNMGNAARYTNCARGARTTYYTNYTNYTNAARAARACNGCNTTYATH ACNGGNGGNGCNGARGGNYTNGGNCARGGNTTYGTNCARAARTTYYTNGARGARGGNGCN AAYGTNTTYTTYGGNGAYATHAAYGARGARYTNGGNAARGCNGTNACNCARGARYTNCAR CARAARTAYGGNAARGAYMGNGTNMGNTTYTTYCCNTTYGAYGTNACNAAYGGNGCNAAY TTYCARGARGCNTTYGAYGCNGCNGTNYTNCAYTAYGGNAAYATHGAYATHTTYATHAAY AAYGCNGGNATHYTNCAYGARGGNATGTGGGARAARATGATHGARATHAAYTTYATGGCN ATGGTNMGNGGNAGYAARATHGCNATGGARCAYATGMGNAARGAYAARGGNGGNAARGGN GGNMGNATHATHAAYATHAGYTCNYTNYTNGGNYTNAARACNTCNTAYACNTCNTCNGTN TAYTGYGGNACNAARCARGCNGTNMGNTCNTTYACNACNTGYATGGCNGARACNCCNGGN YTNGARTCNAAYATGGGNATHGARTTYGCNYTNYTNTGYCCNGAYGCNGTNAARACNTCN YTNACNACNCARYTNGAYGAYGAYMGNYTN------------AARGAYTAYTCNMGNTTY AARGAYATHGGNAARGCNMGNACNATGCCNGTNTCNATGGTNGTNGAYAGYYTNTTYTCN YTNYTNAARMGNAARGAYTCNATHAAYGGNGCNATHYTNATGGTNYTNAARACNGGNGCN AGYTTYCARAARATGGARAGYATHGAYYTNGGNAGYGARTGGCCNATHCCN--------- ------------------------TGYGGNACNGGNCARTGYTGYCARATHYTNAGYGAR AAYCCNATHATGAGYAARMGNGAYYTNAAR---CCNYTNTTY------CCNCCNMGNYTN GCNAARGTNGGNACNTGYGARCCNTAYAARAAYGARGGNGCNTCNTGYGGNCCNTTYGAR AARGCNAAYGGNTAYTGYAGYTGYMGNCCNGGNACNAARTGYGAYMGNGCNMGNYTN--- ---------AAYAARAGYCAYTCNMGNMGNAARATHGCNGCNCCNMGNCCNGGNTAYTCN CAYAARTTYACNTGYATHAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CARTCNTGGYTNGTNCAYGTNGCNTCNTGYCCNGTNTAYTAYAARTGGMGN GAYATGGGNYTNYTNTAYTGGCCNMGNTGGGTNMGNACNGGNTCNTGY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GGNGTNGCNGCNATHAGYGAYMGN ATHCCNGTNATHGCNTCNGCNGCNGTNGCNYTNTTYATGTTYYTNATHYTNATHATHGTN ATHGTNTTYGCNACNTGYTAYGCNCARTCNTGGATHAARTCNAGYATGAARMGNAGYGGN AARGTNAARATGCCNMGNTCNTAYYTNGCNAARAARAARGARACNAARMGNMGNYTNYTN GCNGARTCNGTNTCNAARGCNGCNCCNCCNGCNGTNAAYGGNAAYGTNCCNATHCCNGCN YTNGAYAAR------------------GARACNYTNGTNGARGGNTGGAAYCAR------ ---AAYACNCARAARATHTAYGARGARAARGAYTAYACNATHGARYTNGGNGAYGARAAY GARGARGARTTYMGNATHGARACNACNATHGTNGAYAAYGARGTNYTNGAYGTNGGNCCN TAYAARAAYATGGGNTCN---ACNAGYGCNAARCCNGTNGAYGGNAAYGTNTAYAAYAAY CCNTAYYTNTAYACNAAYAAYGAYMGNGTN------------------------------ ---------------------------------------ATHYTNGAYAAYGTNGAYATH TTYATHTTYGAYTGYGAYGGNGTNATHTGGMGNGGNGAYTCNGTNATHCCNGGNATHCCN CARGTNATHGARAAYYTNMGNGCNGGNGGNAARAARYTNTTYTTYGTNACNAAYAAYTCN ACNAARAGYMGNGCNGGNTAYAARTCNAARTTYACNTCNYTNGGNYTNGAYGTNCARCCN GARGARATHTTYTCNTCNTCNTTYGCNGCNGCNGCNTAYYTNGARCARACNAAYTTYAAR CARACNGTNTAYATHATHGGNGAR---AARGGNATHGGNGARGARYTNGAYYTNATHGGN GTNCCNTGGTTYGGNGCNGARGCNGAYGAYAAYCARCCN---AAYATGGGNTCNGGNGGN MGNGTNGARGTNGAYCAYGAYGTNGGNGCNGTNGTNGTNGGNTTYGAYMGNCAYATHAAY TAYTAYAARYTNCARTAYGCNCARYTNTGYYTNAAYGARCCNGGNTGYGARTTYATHGCN ACNAAYYTNGAYMGNGTNACNCAYYTNACNGAYGCNCARGARTGGGCNGGNAAYGGNACN ATGGTNGGNGCNGTNTCNGGNTGYACNGGNMGNGARCCNACNYTNGTNGGNAARCCNGCN CCNYTNATGATHGAYTAYATHGCNAARAARTAYGGNATHGAYMGNTCNMGNATHTGYATG GTNGGNGAYMGNYTNGAYACNGAYATHGCNTTYGGNMGNAAYAAYGGNYTNAARACNTGY YTNACNYTNTCNGGNGTNACNTCNGARGAYGARYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNGARGAYTAYGAYCCNGCNGARCCNACNGAR GAYGAYGAY------AGYAAYAARGAYAARGAYGGNAAYAAYYTNTAYTGYCAYGTNTGY TCNGTNTCNGTNTAYGAYGARGARAGYTTYCARMGNCAYYTNAAYGGNYTNAARCAYAAR AAYMGNATGGARAGYATHGCNTCNGTNCAYCAYGTNAAYTCNTCNCARATGAAYTTYMGN YTNAARGCNGARGARCAYYTNMGNAAYATHGARMGNAARGGNGGNMGNGAYCCNGAYTAY TTYTGYAARATHTGYAAYAAYGAYYTNGCNATHCCNTGGGARAARCAYMGNTAYTCNAAY ATHCAYAARCARMGNYTNYTNCARGTNMGNAARGGNTGYGGNTGGTGYAARGTNCAYGAY TTYACNAAYTTYACNGARGTNYTNGARCAYMGNGARACNGAYGARCAYAARAARAAYGCN GARATHTAYGGNAARAARGAYGAYAARGAR---GAYTCNMGNCARMGNATHAARGAY--- ---------------------------------GGNAARGARMGNAGYAARGCNACNGAY AAYAARGAYTCNAARGCNGARGARGARGARGARGAYYTNACNATHCCNGARTAYAAYGCN GAYAAYCCNGTNGGNYTNACNTAYGTNATHCCNGTNACNGGNTAYTTYTGYAARYTNTGY CAYAARTTYTAYAAYAARAARTCNGCNMGNGCNACNCAYTGYCARAGYYTNGTNCAYTAY CARAARTTYAARGARGCNACNGARGARAARATHGCNGCNMGNGARAARMGNYTNGARGAR GARMGNYTNMGNAARGARAARGAR---GCNGARGARGCNATGGARGARGGNGAYGARGAR GARAARGARGARAAYGARAAYGGNAAYGARGGNGAYGAYGARCARGARGAYAAYGARGAR GGNGGNGARGAYGARGARGARGARGAYGARGARGARGARGARGARGARGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATHGAYTTYTGGAAYTAYATHCARCARACNATHGCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CCNYTNYTNYTNAARCCNTAYTAYYTNTCNGTN GTNGAYGGNAAYTCNAAYCARTCNCAYAAYGCNACNGAR------CAYATHGCNAGYYTN ATHMGNGAYTAYGARGARGTNGARGGNAARCARATHAARGARATHATHAGYGARMGNGCN CARACNAARGGNAARGGNGGNTCNGARGGNTAYGARAARTCNCAYGTNAARCAYGGNGAY AARGTNTTYCAYAARTTYTGGAARGARATHCARAARTTYCCNGARCARTGYGTNMGNTAY GARMGNTGYGGNGARCCNYTNYTNGTNCARAGYYTNAAYCCNGCNCARTCNATHATHCCN CCNTGYAGYAARTGYGGNTGYMGNMGNGTNTTYGARYTNCARYTNGTNCCNGCNYTNATH ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYCCNGAYGGNAAYGAYTCN TTYTTYMGNAGYTGYAGYMGNMGNATGAGYAARYTNTCNCARCARTCNCARTCNYTNYTN MGNYTNCARATHACNCARYTNTTYTTYAAYGCNGARAAYCCNGAYATHCCNGAYYTNGAR ATHACNACNATHATGGCNCARTAYATHCARGTNGTNGARGAYGARAAYGAYGARACNATH GARATHCCNAGYGARYTNAAYGGNACNYTNYTNYTNACNACNYTNTCNGCNCARTTYCCN GGNGCNTGYGGNYTNAARTAYMGNAAYCCNGARACNMGNGCNTTYMGNGGNATHMGNYTN GTNGAYGGNGTNYTNCAYCCNGARAAYGGNTCNTGGGGNAAYCAYYTNTAYGTNGCNGTN TTYCCNAARGARAAYAARMGNAARGGNGARGAYGGNTTYGAYAAYCCNGCNGCNAARACN AARMGNYTNGAYAGYCARAARTGYTCNGAYYTNATHGTNYTNGGNYTNCCNTGGAARAGY AAYGARGAYGAYYTNAARAARCAYTTYAGYCARTTYGGNGAYYTNGTNYTNGTNCARGTN AARMGNGAYATGAARTCNGGNCARTCNAARGGNTTYGGNTTYATHMGNTTYTCNAGYTAY GAYGCNCARGTNAARTGYTGYGCNCARMGNCAYAAYATHGAYGGNMGNTGGTGYGAYGTN ACNATHCCNAAYTCNAAR------------------------------------------ ------------------------------------------------------------ ------GARGGNAAYAAYCCNATGATGAGYMGNAARGTNTTYATHGGNMGNGTNAGYGAR GAYYTNACNGTNGAYGAYYTNMGNAAYTAYTTYTGYAARTAYGGNGARGTNGTNGAYGTN TTYATHCCNAARCCNCAYMGNGCNTTYGCNTTYGTNACNTTYGCNGAYGCNGAYAGYGCN CARTCNYTNTGYGGNGARGAYCAYATHGTNAARGGNACNAGYGTNCAYGTNAGYAAYGCN GCNCCNAARACNTCNTAYGAYMGNAGYGCNGAYMGNAARGGNTTYGGNAGYCAYATHGGN CARGGNGGNGGNTAYATGCARCCNTTYGGNGGNMGNGGNCCNGGNCCNGTNGGNGGNAAR GCNAAYGGNGCNGAYGGNGGNATGGCNGCNAAYAAYYTNGGNATGAAYYTNATHAAYTCN GCNATGYTNGCNGCNGCNCARGCNATGYTNGCNAAYCCNAAYAGYTGGAGYGGNATGAAY CARGGNACNCARGGNGGNAGYGGNGGNAGYATGGGNGGNGGNGAYCAYCCNTCNTCNATG GGNCARGTNTCNAGYCARGGNGGNTTYGGNAGYATGGCNGCNGGNACNGGNGGNGGNTCN GGNAGYGGNAAYTGGTGGGGNAAYGARGGNAGYTCNTCNTCNGGNGGNCAYTAYGGNGGN TGGGGNGGNTCNCAYGGNGGNMGNGGNGGNAGYGGNTGGAGY---------------YTN ACNYTNGARCAYCCNGTNTTYMGNGARTTYATHGGNTAYGCNACNATHYTNATHYTNAAR ACNYTNTTYYTNGGNYTNYTNACNTCNTTYTAYMGNGTNACNAARAARATHTTYGCNACN GARGARGAYGTNTCNTAYTTYCARGTNAARAAR------AARGGNATHGTNYTNGAYGAY ---CCNGAYGTNGARMGNGTNMGNMGNGCNCAYCARAAYGAYYTNGARAAYATHCCNYTN TTYGTNYTNYTNGGNATHATHTAYTGYACNACNAGYCCNGCNYTNTCNGTNGCNYTNYTN CAYTTYMGNATHTTYACNGTNGCNMGNYTNGCNCAYACNGTNGTNTAYYTNTTYAARGTN CCNCARCCNGCNMGNGCNGGNGCNTTYTTYACNGGNATGTGYATHAAYYTNTCNYTNGTN TTYCARATHYTNTTYAARATHGCNTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CCNGGNACNATGGTNGGNGGNGGNAGYCCN AAYCARGARGTNATHTAYTCNGGNAARCAYAAYGGNATHTAYATHTTYTTYAGYMGNATH YTNMGNCCNTTYTGGGARTTYCCNGTNACNACNGARTTYATHCAYGAYTCNAARCARGGN AARGTNACNTTYYTNACNTCNAAYTTYACNGTNGARGARYTNMGNACNGCNYTNGARATG GTNMGNGAYYTNTCNGAYTTYGTNGAYTTYAAYTCNAARTTYGAYGTNGAYTCNCAYGTN GAYATHATGAAYACNGGNMGNGGNMGNYTNGARGGNAGYATHGAYGARCARAGYMGNAAR MGNATGCARATHGARGTNCARMGNATGGARAARATHTCNYTNCARCAYYTNCARGAYYTN YTNCAYMGNACNGARGARGTNYTNGGNYTNTGGMGNYTNYTNATHGAYCAYCARTTYCAY ATHYTNGCNGCNGCNATGGCNCCNGAYATHCARAAYCARYTNMGNCAYATGACNTTYAAR AGYYTNGTNACNAGYGGNAARGARGTNTGYAGYACNYTNATHATHTGYYTNGTNAGYMGN TAYYTNAAYGAYAAYGCNACNATHGAYGCNATHAAYGAYMGNYTNMGNGARGTNTGYCCN ACNYTNTAYAGYACNGAYGAYGCNACNTGYTCNAARTCNAAYGARYTNYTNCARGCNGCN AARATHAAYCCNAAYCARYTNGARAARGARCAYCARYTNCARGARGCNYTNCARYTNYTN AARGGNGTNTCNCARCCNYTNAAYYTNTCNGTNATHTGYTCNCARYTNGCNAGYGTNCAR TTYTAYYTNGGNATHGTNGARYTNGCNYTNAAYGARGCNGGNAARYTNGAYCCNCARGGN ATGGCNATHCAYTTYTAYAAYAGYGGNGARCCNCARGARGAYATHCARGGNATGCARGTN TAYATHGGNMGNATGGAYTGYTAYAARTGYATHACNGAYACNYTNACNTAYYTNAGYGCN GCNAGYACNAGYCARGCNCARGTNCCNAAYAAYCCNTTYYTNGCNTCNTCNGCNGCNAAY GCNGARACNAAYAARATGGARCCNCARCARGCNGARCAYTTYMGNGARGARGTNTTYGCN ACNGCNYTNMGNTGYGAYGAYTCNYTNTTYCAYGCNGCNYTNTAYGARTGGYTNTTYAAY ACNAAYCARGCNGAYAARYTNYTNGARATHAAYACNCCNTAYGTNGARCARTAYYTNMGN MGNAARGTNAAYYTNCARACNGAYAAYACNGGNGCNYTNGAYATGYTNTGGMGNTAYTAY GARAARGTNGARAAYTTYCCNGCNGCNACNMGNATHYTNTCNCARYTNGCNGARMGNCAY GGNACNAAYGTNAAYYTNACNCARMGNYTNGARTAYYTNTCNMGNGCNGTNGTNTGYGCN AARAGYTCNACNTCNMGNYTNGGNACNTCNGCNGGNGGNGARACNYTNCAYGARYTNGAR GARAARATGGARGTNGCNMGNYTNCARATGCARATHTAYMGNTGYYTNTGYAAYATGATG GCNACNCCNCCNGTNGARAGYTCNAARGCNMGNYTNGAYGCNGARYTNYTNGAYATHACN ACNYTNTAYGARGARTTYGCNGAYCCNTTYGAYYTNCAYGARATGAARYTNGCNATHGTN CAYTGYGCNGGNYTNTAYGAYGCNGCNYTNATHGARGAYYTNTGGMGNAAYATHATHGAY AARGARATHAGYAGYACNTCNCCNATGTCNGGNTCNGAYMGNATHAGYACNATHGGNACN AARYTNTCNACNGTNGCNAARYTNTAYGTNAGYGCNGARMGNTAYTTYCCNGTNGCNATH ATHYTNMGNCAYYTNGARGARAARTCNTGYGARYTNGCNYTNGAYYTNGARTGGGTNTTY AARATGATHYTNGAYGTNGGNGTNGCNCCNGGNMGNYTNYTNGARYTNTAYGAYMGNYTN TAYAARTCNAARGAYGTNGTNTGGCARACNYTNGGNMGNCCNYTNCAYYTNYTNATGGTN YTNCARTCNTTYATHGAYCAYATGGCNMGNAAYCCNGTNYTNYTNMGNAAYGCNAGYCCN CCNATGCARGTN---TGGTGYYTNGAYYTNGTNGCNTCNTAYYTNGTNGAYYTNGGNGCN YTNGGNACNTCNACNMGNGAYGTNGCNCCNYTNATGGCNGGNTTYAARGCNACNCARGCN AARYTNGARMGNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TAYGGNCCNACNCARGTNAARACNAGYMGN------GARGAYGAY TCNACNTTYAAYYTNTGYCCNGGNGARGCNAARACNYTNTCNATHCAYTGYGAYGTNGAR ACNGTNTTYCCNAARCCNAAYATGACNYTNMGNGGNCAYCCNGAYGGNGGNATGAAYCAR GARAGYGTNAARAAYAAYTCNTAYMGNTAYACNTTYTCNGTNMGNCCNCAYGTNAGYGGN AAYGCNCCNTTYACNTGYGTNGCNGTNAAYAGYGTNGTNGGNAAYYTNACNAGYGARGCN YTNYTNCAYGTNCCNGTNAAYGCNCCNCCNGARACNGCNCCNCAYGTNGTNATHAAYGGN ACNACNGTNACNTCNGARACNCAYGARMGNATH--------------------------- MGNATHACNTGYGARGTNAARGGNGGNCARCCNGTNGTNAGYGTNACNYTNGAYTGYGAY CAYGGNAARAARTCNATHGCNAAYAARTCNATGGTNTCNTTYGTNGGNTCNAARGCNATG AGYGGNATGGCNTGYGTNTGYMGNGCNGARCAYGTNTCNGGNTGYTAYYTNYTNACNACN GTNAARGAYTTYCAYATHCCNATHACNCAYGCNAARGGNMGNGCNAARGTNMGNGARATG TTYATGAARAAYAARCAYGTNACNGAYATHMGNGTNATHGAYATGYTNGTNATHAARGGN CARATGGARYTNGTNGARACNGCNAAYATHTGGAARCARMGNCAYCAYATHATGGCNTAY TTYAARGAYACNGTNAAYCCNAARCCNACNGAYTTYYTNAGYAARTTYTAYGARGGNCAR GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TTYGGNMGNAAYATGAAYTCN GGNGAYATHATHTTYMGNMGNATGTCNGGNCARCCNYTNTAY------AGYCAYGTNGAY CARGARYTNGAYCAYAARGTNAARAARGTNTCNGAYMGNTTYTCNGARACNGTNAAYATG GTNGCNAAYGARCCNTCNYTNGCNTTYTTYMGNATHCARGARCAYGTNMGNAARACNYTN CCNCARYTNGTNGAYACNAARCAYGARGTNGARGARGTNCARACNAARGTNCARGGNGCN TGYTTYGAYGCNGAYTAYGCNGTNAAYGCNGTNAARGCNATGCARAGYAGYGCNATHCAY TTYCARAAYATHCARGAYYTNYTNAARAAYGCNATGTTYATG------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TTYGCNGCNYTNAARCCN GARGARGARYTNATHGARGARMGNMGNGCNCARMGNAARYTNGARCARCARAAYAAYAAY AAYAAYGCNTTYAARAARAARGAYGAYAARMGNAAYAARTCNAARGARAARGARAARYTN CARCARYTNGCNTTYGGNTTYGGNMGNCCNGGNTCNGCNAAYTCNGARCCNGCNAARGCN TCNGCNGGNAAYCARAARGTNCARGARCAYGARTGGCARCARTGGAARGARCAYGAYCAR GARGTNGTNGARGAYCARTTYMGNGARGAYYTNGARAARGCNYTNYTNGARAGYCARYTN CARYTNGARCARACNAARATHGTNGAYAARCARAARAARGARMGNGTNAAYGGNAAYCAY GARGARCCNGCNGGNGGNGARGARGGNAARAARAARAARAARAARGAYAARGCNAARACN ATGTCNYTNGARGARTTYAAYAAYYTNCARAARCCNAARACNCARAARGCNCCNGARGAY YTNCAYGAYGARGAY---------YTNTCNMGNCCNCCNATHCAYCAYMGNGTNCCNACN GCNGARAARGAYTCNAARTTYTTYAAYAGYGCNCARCAYGARGCNAARCARATHYTNAAR AARGAYAARATGCARGARGARTAYMGNAARACNTTYGCNGTNGAYAAYGCNGTNGTNGCN AARYTNAARAAYGAYATHGARATHMGNGAYAARACNATHAARGAYYTNAARCARAARATG GARAARATGGARAAYGARATGAARCARGTNAARCARMGNAAYAARCARYTNTGYGTNATH YTNGCNCARGGNGARATGAARGAYAARGCNCARGTNYTNYTNCARGTNGAYGARYTNAAY AAYGTNAARGAYGARYTNATGGARCARGTNACNTCNYTNACNGCNGARYTNGARAARGAR AARTCNAARAAYMGNGCNYTNAARCCNGARACNGARAARGTNAARACNGGNAARCCNGGN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNYTNMGNTAYYTNAGYACNCCNMGNGGNCCNAARAAR GAYAAYACNACNTAYAARTGYTAYCAYTGYTCNTAYACNGCNAARMGNCAYTCNTCNATG AARTCNCAYATHTAYTAYAARCAYMGNGGNAARGGNYTNYTNGCNGTNGAYGARGAYACN AGYACNGGNGGNCARGTNTTYTTYTGYGCNMGNGAYGAYTGYACNTTYAARTCNACNAGY CCNACNTCNTAYYTNAAYCAYGTNGARCARTGYACNCCNTGGCAYAARCCNGARYTNGCN GAYGTNGARGTNGARCCNCAYATHMGNGARTGYYTNCARCARACNGTNACNTTYGCNGAR ATGGCNYTNGAYAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNGGNYTNYTNCCNGAYAARCAYYTNGGNATGGAR YTNCARGAYATHTTYCCNCAYATGGTNAARATGAARGARAARTTYGGNYTNAAYGARTGY GGNGARGGNGGNGARTAYGARACNTTYGTNTAYGAYTGYCCNYTNTTYAARAARTCNATH YTNATHGARGARAARGARCARGTNATHCAYTCNGAYGAYGCNTTYGCNCCNGTNGGNTAY YTNAAYYTNAARAARTGYMGNYTNCARGAYAARCCNGARCAYGAYGTNTCNTCNTTYGTN AARGARATHGARAARTAYCCNATHACNACNACNTCNAARTGGYTNACNAGYCARYTNGCN CAYGAYGAYGGNAAYAAYTTYGARGCNGGNATHGGNGAYGTNYTNAAYGTNACNGCNTCN CARCAYATGTCNGTNGARGAYGARGCNGARYTNATHCCNTCNTAYGCNAAYGAYGGNAAY GGNTTYTAYGTNTCNGGNATHMGNCCNACNTCNCARTCNATHTCNGAYGTNTCNCARGCN ACNATHTCNGCNYTNGAYACNYTNMGNGGNTGYATHGGNGCNATGGGNCAYGCNATGTCN GAYGTNACNTCNGTNTCNYTNTAYGTNGGNAAYATGTCNAAYTAYACNGCNATHAAYACN ATHTAYAARAAYTAYTTYGARATHAAYCCNCCNACNMGNATHTGYATHCARGTNTGYYTN CCNCCNACNGTNYTNTTYYTNYTNGAYTGYGARGGNATHAGYACNGARTCNGAYGAYMGN AARACNATGTAYGTNCARAGYYTNTCNYTNTGGGCNCCNGCNAAYYTNGGNCCNTTYAGY CARTCNATHTCNYTNAAYGARAARATHTGGGCNTCNGGNACNACNGCNYTNGTNCCNTCN ACNYTNAARYTNATHGAYGCNGGNGTNAARGTNCARAGYMGNGTNGCNYTNAAYCAYYTN YTNGARAARTTYTAYGGNGTNTGGCCNTAYTGYGTNGTNGGNAAYTCNCCNYTNATHTAY TGYTAYATHACNAARMGNGAYCAYATHCCNGTNGCNMGNMGNGARTTYGARGCNATHYTN GARGARAGYGGN------CCNGGNGCNYTNAGYTTYACNCCNACNATHCARTAYTGYGTN GTNCCNMGNYTNCCNCARGGNGCNYTNGTNGARTGGCARGCNTAYGCNTGGATGTTYACN ---------GAYTCNAAYGCNGARGGNACN---CARTCNAARAARAGYTAYCCNCAYTGG TCNATGGARYTNGAYTGYTTY------------TGGTTYMGNGARCAYATHGARGTNTGY TCNAGYACNCCNGAYGARATHAAYYTNCARGARGTNTCNAGYACNYTNYTNYTNGARTAY AGYAARATGCARAARAARMGNAARACNAARGCNAAYMGNGGNYTNGCNAARATHTTYTAY YTNGTNGAYAARTTYTCNTAYMGNGAYYTNGTNAARTGYTTYTCNCARATG------ACN CCNGTNGAYTAYYTNAARATHCCNATHTTYTCNTTYATHCCNGTNACNAGYYTNGAYACN GARCARCAYATHYTNAAYTGGTGYCAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARGGNAGYAARATGGCNYTNCARAAYCARGTN GARCARYTNMGNGCNCARYTNGTNMGNGCNGARCARGAYMGNCARMGNATGMGNATHGAY YTNGAYGARTCNMGNGTNGARGCNGARGTNAARGARMGNMGNMGNAARMGNAAYGCNGAR GAYGAYMGNAAYMGNGCNYTNGARAAYGAYYTNYTNGARATGAARTCNCAYYTNGTNMGN TCNGTNGGNGCNATGTCNGARATGGARGARGTNAARMGNMGNYTNGARAARAGYGARMGN CARMGNACNCARYTNTCNGAYCAYATHGARACNYTNGTNAARGAYYTNGARAAYMGNGAR MGNCARAGYGCNAARATHATHAAYCARYTNAARGARACNTCNGAYAARTAYGARGAYTCN GAYMGNCARMGNTCNYTNATGTCNACNCARYTNGARGAYATHCAYCARAARYTNAARGAY GTNACNMGNGARYTNGARAARACNACNCAYGARYTNMGNAAYACNCARYTNYTNYTNGCN GARACNGAYAARAARAARGAYGARTTYAARGGNMGNGCNCARGARACNGTNMGNCARTGG AARGCNAARGTNAARCARYTNGARMGNGAYYTNGAYMGNCARAARCAYGGNAAYGGNCAR ATGATGGCNMGNCAYGARCARYTNGTNAARGARATGGARGGNCARAARCARCAYGGNACN TAYAGYCARYTNCARYTNGARAGYYTNAARMGNGARYTNGCNGAYGCNYTNGCNGTNMGN GCNGCNCARGAYGARCARYTNMGNYTNAARGAYATHGARGTNAAYGARYTNAARTCNTTY MGNATGGAYYTNGARMGNGARTAYMGNGAYGGNMGNACNATHACNGARAARGTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CCNTTYCARCAYGCNAARGTNGGNTCNTTY TTYCARACNCARCCNGARYTNMGNAAYCARTTYAARGARGAYGCNTTYYTNCARAGYTTY YTNCARACNCAYGTNTCNAARGARTAYYTNTCNGGNGTNGARTCNGAYYTNTCNMGNTTY GGNGAYMGNGTNGCNGGNGAYYTNTTYGARYTNTCNATHCARATGGARGCNGARAARCCN MGNYTNGARCARTAYGAYGCNTGGGGNCAYMGNGTNGAYMGNYTNATHACNTCNAGYGCN TGGAARAARATGAARGARGTNTCNGCNGARGARGGNYTNGTNGCNTCNGGNTAYGARMGN AGYTTYGGNGARTGGAGYMGNYTNTAYCARTTYTCNAARTTYTAYYTNTTYGARCCNTCN GCNGGNYTNTAYACNTGYCCNYTNGCNATGACNAAYGGNGCNGCNMGNACNYTNGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CARATHYTNMGNCARGCNTCNGAY TAYATHATHMGNATGMGNGAYAARACNTCNCARAAYGAYMGNCAYATHCARATHYTNAAR CARCARAAYGAYGARYTNCARGCNCAR--------------------------------- ------------------------------------------------ATHAARGCNYTN CARAARTCNCARTCNGGNGGNAARGCNYTNATHAAYTCNAAYTTYYTNGAYGAYMGNGGN GAYGAYGAYTAYGARAGYTAYGARGAYGARCCNGTNGTNGCNTCNCCNCCNAARMGNAAR AARACNAARACNAGYCAYAGY--------------------------------------- ---------------------------------TTYATGATHGTNGGNYTNGGNAAYTTY CCNCAYCCNGARACNMGNCAYAGYATHGGNATGAARGCNYTNGAYAAYTTYACNACNAAR YTNGGNYTNACNTGGGARAAYGTNCARGGNMGNCARGGNGGNYTNYTNTGYMGNGGNGTN GARGGNAARGAYGARAARGARYTNACNCARATHTAYTTYTTYAARCCNAARTCNYTNATG AAYATHTGYGGNGGNAAYGTNGCNMGNACNGCNAARTCNYTNGGNYTNATGTCNGAYTCN ATHTAYYTNATHCAYGAYGARYTNGAYYTNGCNYTNGGNAARGTNTCNATHAARAAYGGN GGNAGYGCNAAYGGNCAYMGNGGNGTNYTNTCNTGYATGTCNGAYYTNAARTCN------ ---------------MGNGGNYTNTGGCCNAARGARGTNGCNGAYACNGAYGGNYTNCCN MGNYTNMGNATHGGNATHGAYMGNCCNGCNTCNAARTCNGARATHATHCCNTAYGTNYTN GGNCCNATHCCNAGYCAYGARATHAARGTNACNGARTCNGCNGTNGARAARGGNATGGAY YTNYTNATGMGNCAYATHGCNGAYMGNGTNCCNCCNAAYAARCARYTNMGNATGCARAAR MGNATHCCNYTNYTNAARGARMGNCAYCCNCCNGTNTTYCARTCNCCNCCNMGNAARGTN ACNTCNACNATGACNCCNCARTCNCCNCCNCCNGCNCCNMGNGTNGARACNTCNYTNGAY GTNAARGCNACNYTNAARGAYAARGAYYTNAARGAYGTNYTNGGNGAYGTNAARGCNCCN MGNAAYGAYAARACNGTNTCNAARAARGAR------GARAARGTNGGNATGTCNGTNATG AAYGARTCNGTNCARACNAAYATGAARAARGGNATHGCNCARGCNTCNCCNGARGCNCCN GCNGAYTAYGCNYTNAARTAYAARGCNGGNGTNGCNCCNTCNMGNACNATHAARAARTTY TCNGARTAYCARAARCARTTYCARTGGAARCAYGGNAARAARGCNTCNCCNYTNYTNGCN GCNGARCARATHGTNTAYACNAGYAAYACNGARYTNGGNCCNTAYAARACNGARGCNATH CCNAARGTNTCNGARTAYMGNMGNGARTTYCARMGNTGGAARCCNACNGARGTNAGYAGY AGYYTNAAYYTNAAYGCNAAYAAYAAYAAYAAYGAYCARGAYYTNAARMGNAARGCNGTN GTNAARMGNAGYAARAGYGCNGGNGCNGAYYTNMGNAARGCNGAYGARTCNGAYGAYAAR GARGAYGTNGCNGCNGAR------------YTNAARGARAARYTNAARAARAGYCAYGGN AARATGMGNMGNACNGGNTCNGARTAYCARTCNAAYTTYAARGCNCCNTCNTGYTAYTAY AGYAGYAARGGNGCNTGGAARGGNGCNGAYCCNCCNCARTTYATGCCNGTNGCN------ CARGARGTNAARAARGAYGTNGARGCNAAYGCNAGYAGYAARGGNGARACNGAYGCNCCN YTNTCNAAYTGGTTYGCNGARGTNGTNGARYTNMGNMGNMGNGCNGAYGARTAYMGNAAR MGNGCNCARGGNACNCAYTTYTCNMGNGARCAYYTNGTNCARYTNATGGCNCARCARAAY GARTGYTGGGAYGTNGARTCNCARGCNTCNTCNATHGTNAARGCNYTNAAYYTNGARGCN CCNAARATHAAY---------------AARAARYTNCARAARGARGCN------------ ------------------------------GCNGAYTCNCCNGTNYTNTCNGAYATHGAR YTNGARGAYATHGARGARGARGARYTNGARCCNGCNGTNGTNGTNAARAARACNTAYAAR ACNTCNTCNMGNGAYGCNAARMGNATGGCNMGNATGAARAARGAYAARGARGCNGTNTCN CARCARCARMGNAARATGAARGARGARAARGARATHGARYTNGGNGARGAYGGNGAYGAY AAYTGYAGYGAYGAYATHGTNGAYGARGARGGNMGNCARCCNACNCCN---AARYTNAAR CARTCNGGNTCNTCNAGYMGNCAYCAYYTNGAYYTNACNACNCCNGCNGTNGGNGGNGCN YTNYTNACNTGYCCNCCNCCNAARAGYAGYAARATGATHGTNACNTCNMGNTCNGGNGAY AGYTAYGTNACNGCNTCNGAYAAYYTNGARGTN------CCNCARAARAARTTYGAYATG GAYCAYYTNAARACNMGNCCNATHYTNGGNCARCCNTCNGGNGAYACNCAYGCNYTNMGN GAYGAYGAYGCNTCNTCNGAYMGNCCNYTNAAYACNMGNTAYGTNCCNTCNCCNGCNYTN GCNTCNAGYGAYGARGAYAARGARAAYGCNCCNGCNAARCARAARYTNTCNAARACNACN AARCCNAARAGYYTNACNCCNGTNCARGARGGNGTNGGNAARACNTAYATHAARTCNAAR CCNTTYYTNACNYTNGAYGAYATHMGNGCNAAYGARAARAAYGTNGCNGARGAYGAYGTN ATGTCNGTNTCNATGATGTCNGTNGCNTCNAGYGCNTCNYTNGCNTCNGARGTNYTNGAR MGNGCNMGNAARMGNCARAARGARTTYTGGGGNAAR------TTYYTNTAYTTYGGNTAY GGNAGYAAYATGYTNGARGARMGNATHCAYATHAARAAYCCNTCNGCNMGNTAYATHGGN AAYGGNACNYTNAGYAAYTAYAARTTYGGNTTYGAR------AARACNGTNTGYATGGCN GAYGTNGGNGCNGTNACNACNATHMGNCCNTCNGARCAYGAYGTNGTNAARGGNTGYGTN TGGGARATHGAYGCNGAYCARGTNGCNAAYYTNAAYMGNCARGARATHCARTAYAARGCN ATHTAYGTNGAYATHCARATGGARGAYGGNAGYACNYTNTCNTGYMGNACNTAYGARATH AAYMGNGARGTNCAR---CCNGAYACNAARCCNCAYCCNTTYTAYCARMGNATHTGYGTN GARGGNGCNAARCARCAYCAYYTNCCNGAYTGGTAYATHAARTTYYTNGARAGYTTY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARATHATHGAYCCNAARACNAARATHATG ATGCAYCARTAYCCNYTNCAYMGNATHTCNTAYTGYGCNGAYGAYAARTCNGAYAARMGN ATGTTYACNTTYATHGGNAARGCNGCNGAYAAYAAYGAYCAYTTYTGYTAYGTNTTYGAY AGYGARAARTGYGCNGARGARATHACNYTNACNATHGGNCARGCNTTYGARYTNGCNTAY AARMGNTTYATHGARTCNTCNACNCARGAYYTNGAYYTNAARAARCARTTYYTNYTNYTN CARAARAARGTNAAYACNYTNCARTTYGARAAYGAYGTNYTNAARAARMGNYTNGCNGAR YTNGARAARYTNAARGAYMGNTCNGAYGTNGARCARTAYAARAGYAAYAAYCARATHAAY GAYATHGCNACNGTNAARYTNAAYYTNMGNGARAGYTCNACNGAYGARGARGAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYTCNTCNCARGARTCNCCNTCNGCNMGNGGNGTNAARMGN ACNCAYGARGARGTNGARGAYATHAGYGARAGYTCNAAYTCNCCNAARCCNTCNCCNCAR AARAAYAARAARMGNTGYTTYACNTGYAGYTGYMGNYTNGARYTNGCNCARMGNACNATH GGNAARTGYMGNTGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN GTNYTNCAYACNCAYCCNGTNCAYMGNATHTCNTTYATHTCNMGNGAYACNACNGAYAAY MGNGCNTTYGGNTAYATHATHGGNACNGGNGAYGGNAAYCAYACNTTYTTYGCNATHAAR ACNGCNGCNGCNGCNGARCARYTNGTNYTNACNYTNMGNGAYYTNTTYCARGTNGTNTAY GARATGAARAARAARGARGTNGAYGARGCNAARGARAARYTNGARAGYGARACNGTNAAR GARGARATHAGYACNGARAAYTCNAARCCNTCNGGNGARGGNTCNACNTCNGARGARGCN CARACNCARAARACNCARGCNGCNGARGCNGAYGGNATHTAYCAYGTNCCNCCNAAYAAY GCNCCNGTNAAYGGNAGYYTNGARGARCARCARGCNAAYYTNYTNGAYYTNGARGAYCAR GCNGAYTCNATHYTNAARGGNATHGARCARATHAARAAYYTNGARTTYGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGTCNGGNATHACNTGYYTNGCNTGYAAYGTNGCNTTYGARGAY GTNGAYYTNGGNMGNATHCAYTAYAARACNGAYTGGCAYMGNTAYAAYYTNAARMGNAAR GTNGCNAGYYTNCCNCCNATHACNYTNAAYAARTTYGARGARMGN---------CARAAR GCNCARGARCARYTNGAYACNACNTCNAARGARGARMGNTGYTCNTGYAARCCNTGYAAY AARTGGTTYAAYACNACNAAYGCNTAYGARAAYCAYYTNCARTCNAARAARCAYAARGAY GTNATHTCNGGNGTNGCNCARTCNAARAARGAYAARAARAARAARGCNGGNCCNAARGCN GCNATHGCNTCNTCNCARYTNTCNAARCAYAGYGARGAYGARGARGARGAYATGACNGAY GAYGARGAYGAYTCNGAYGCNGARTCNTGGGAYAGYTAYGAYGARAARATHATHGCNYTN GARGARTGYYTNTTYTGYTCNYTNGTNAGYTCNTCNYTNGARGAYAAYCARAARCAYATG ACNTCNACNCAYGGNTTYTTYYTNCCNGAYGCNGARTAYATHTGYGAYYTNGARGGNYTN ATGACNTAYYTNGGNGARAARGTNGGNGCNGGNTGYGTNTGYYTNTGGTGYAAYGARAAR GGNMGNMGNTTYMGNAAYTCNAARGAYGTNCARAARCAYATGGTNGAYAARGGNCAYTGY AARATHTTYCAYGARCARGARACNYTNTTYGARTTYACNGAYTTYTAYGAYTAYTCNAAR AGYTAYCCNACNGTNGARGGNGARGARCCNGAYATHGAYTCNACN---GARAAYGTNGAY ATHCARGARYTNGAYGGNGAYGGNTAYTCNYTNACNYTNCCNTCNGGNACNGTNATHGGN CAYMGNTCNYTNATGMGNTAYTAYMGNCARAAYYTNGCNCCNTAYMGNCAYGARAARACN AARACNGTNYTNCCNAARATGYTNGCNCAYTAYAARGCNYTNGGNTGGACNGGNGCNACN GGNCCNYTNGTNGARMGNMGNGCNAARGAYYTNCARTAYATGCARMGNGTNMGNAAYMGN CAYTTYATGAARYTNGGNACNCARGGNAAYAAYYTNMGNYTNMGNYTNMGNCAYCARAAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CCNACNTCNYTNGTN TCNTGYYTNGARGARTTYGTNGARYTNAARCARACNGCNGARGGNGARYTNGAYGARAAR GARGARGGNGARCCNMGNGAYCARGARAGYGARMGNACNYTNGARGAYATHGARGARGAY TTYAAYAARTTYAARAARGARMGNAARMGNGAR------------------AAYGCNGAR GCNATGGARGGNGARGAYGARGARGARGARAARCCNAARGARTGYCCNAARCAYATHCAY ATHGTNAARGARGTNYTNTCNMGNGTNAARAAYYTNYTNTCNTCNCAYGAYGCNMGNATH MGNGTNCARTCNYTNGARGTNGTNGCNCARAGYTGYAARGAYYTNGCNGAYCAYGARMGN GARYTNYTNCCNCARATHCAYAARGTNTGGCCNGGNTTYTAYCCNMGNTTYTAYAGYGAR GARAARTTYGTNGTNATHAARGCNYTNGARACNYTNMGNACNATGGTNGAYGTNAGYGGN AGYTTYATGYTNCARMGNGTNATGAARGAYGTNATHCCNAAYYTNTCNGTNTTYATGGAR AAYCARGGNAAYATHAGYAGYGAYAGYMGNTCNACNTAYATHAAYACNGCNAGYTTYAAR YTNCARYTNGCNATHYTNGARTCNYTNGGNTCNYTNGCNGARAARYTNCARYTNAGYGAR MGNAAYYTNCAYGTNGTNGCNAARATHTGYYTNCCNTAYYTNAGYTGYYTNCARCCNGAY AARYTNCARAARGCNAGYATGTCNTCNTTYAAYTCNTTYATHTCNYTNGAYTCNGAYGCN ATHTGGYTNATGYTNTGYCARGCNTGYTGYCCNTTYGARTAYCARATHCCNGGNACNGAR TTYATHCCNYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARGAY CCNAARAGYGTNATHAARTAYYTNYTNACNTCNCCNGTNGCNGGNACNCCNCARACNGTN GCNGGNACNCCNCARACN------ATHTCNCCNYTNGCNATHGAYAARCCNAARGARACN TCNACNCCNGTNGTNCCNACNAARAARTCNAGYAARAARATHAARTTYGARGAYGGNACN CCNCCNCCNAARAARAARGARAARAARATGAARATHGARATHATGTCNCCNTCNGARATH AARCCNGCNGTNTCNTCNGCNCCNYTNGCNGARCCNAARGCNCCNAGYYTNAARATGAAR ATHATGTCNGGNTCNAAYCCNATGACNGCNCARGTNGCNATGGAYTCN------CARGCN AGYGARGTNAGYCCNGCNCCNAARGTNAARAARACNAARAARGTNAARAARGARACNAAY ATHAARAAY---------GARGAYGTNAARCCNGAYATHACNGGNCCNGTNGAYGAYGGN GARAARGCNCCNAARAAR------------AARAARGTNTCNAARAARAARGARAARYTN ATHCARAAYGCNATHAGYGCNGCNTCNTTYGTNATGCCNCCNCARGCNGTNGTNATGGGN ---GAYTCNCCN---------------------TCNCCNGTNGCNGTNAARCCNAGY--- ---------AARAARAARGTNAARAAYTCNTCNCCNGTNAARTCNGARCCNAAYACNAGY GAYTCNYTNGTNATGGAYTTYGAYGAYACNGGNATGGARGAYGARGGNGARGARTCNACN YTNGTNATHGCNGARACNGARAARAARAARAARAARGCNCCNTCNAARAARAARAGYCCN AARGARAARGGNGGNCCNGARACNCARAARGARGARAAR---GCNAARAARATHCCNAAR MGNGCNCCNACNGCNTAYATGYTNTTYTGYAAYGCNCAYMGNCCNGCNATHGTNGCNGAR AAYCCNGGNATHGARTTYGCNGGNATHAGYMGNAARYTNGGNGARYTNTGGCARACNCAR TCNAAYAARCARAARYTNCARTGGMGNMGNAARGCNCARMGNMGNATGAARAARTCNAAY YTNATHTCNACNGGNAARACNGGNGGNAARGARTCNCARTCNACNTCNGCNCCNCCNACN GCNACNCARGGNGTNGGNACNYTNAGYTCNAAYAARAARYTNGCNYTNATGYTNCARAAR AGYAARCCNGTNGTNGTNGARGARGGNCCNYTNAGYCCNACNAARAAYTTYAGYATHGAR CCNYTNGAYGTNGCNGCNCAYYTNAARYTNYTNGGNGARTCNYTNAGYATHATHGGNATG MGNYTNCARGARCAYAARGGNATGATHGCNGTNCARGGNAGYYTNTCNGTNYTNYTNGAY TCNYTNYTNTGYGCNTGYGGNCCNYTNYTNTGYYTNACNCARCARGTNCCNGGNATGGAY GGNTGYTCNCCNYTNGTNCAYGCNCARACNYTNGAYAGYGTNGCNTAYGTNATGCCNGGN YTNGARYTNTGYGCNTAYGCNGTNCARTCNGARYTNGGNGAYTTYGAYCCNMGNATHAAY ACNCCNGGNTAYGTNTCNGARTTYAGYTTYGTNCCNAAYCARACNGARGARYTNGARAAY MGNATHGCNGCNATGCAYMGNMGNTGYGTNGGNGCNACNCCNYTNATGGCNGARCAYMGN TTYYTNGARAARTCNAARTGGYTNGARATGTAYGGNGTNGAYYTNCAYCCNGTNCARGGN GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AGYATHCAYCCNAAYGCNCCNCCNCCNCCNTAYACN GGNGGNGAYCCNTCNTAYCCNCCN---CCNCCNGCNGGNTTYTAYGGNGCNCCNCCNCCN CARGCNTAYGGNGCNCCNGCNGGNTAYGGNCCNCCN------GGNTAYGGN---CCNCCN CCNCARGGNTAYGGNGTNCCNACNCARCCNGGNTAYGGN--------------------- ------------------------CARGCNCCNTAYCCNCARCARCARTAYCAYCCNCAR ------------GGNCAYTAYCARCARCARCCN---CARCARGTNGTNTAYGTNMGNGAR GARMGNMGN------GARAARGAYAAYAGYGCNGARACNTGYTGYATHATHGCNYTNTGY AGYGCNYTNYTNTGYTGYTGYYTNATG--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------MGNMGNGGNTTYCAYGARMGNGAYTCNCAYMGNGARGTNMGNAAYGGNGAY ACNAARGAYAARGAYAARGCNTCNGARAARGAYMGNCCNTTYAAYGAYGAYTTYCCNTCN YTNAAYGGNTCNGGNGARTCNTCNGTNGAYTCNAARGCNAARCCNGCNTCNGGNGTNTGG GARAAYCCNCCNAARTCNTCN---AAYAARAAYGARGARTCNACNGAYYTNYTNAARAAY ACNTCNCCNGGNATHTAYAARGCNYTNGTNCCNAGYAARAGYGTNCARTCNAARAARCCN GTNAARGAYATHCCNMGNGTNAAYGGNAGYGTNMGNGARATHTCNCCNYTNAGYCCNTCN AAYAARCCNGGNCAYMGNGARGGNTCNMGNTAYAGYCCNACNCCNGAYYTNGCNATHGTN ACNCARCCNAARAARYTNGGNGAYAARAARAGYGAYTTYYTNMGNGCNATHMGNAAYGAR AGYTCNATHMGNAAYGGNGAR---------GTNCARAAYCARAAYGTNGARMGNAARCAR GARTCNAARCARGAYACNAAY---------------GARGAYGTNAAYACNTTYACNCAY ATHAAYGGNGAYMGNCARGTNGAYACNAAYGARAAYYTNGTNAGYYTNAARAARGGNGGN YTNAAYGGNGARTGYAAYGAYGARTAYATHAAY---------GGNGARGCNYTNATHAAY CAYGTNGAYCAYATHACNYTNTCNGGNGARGARGARGARMGNMGNYTNYTNYTNTCNATG GGNTGGGTNGARGARGAYAAYACNGARTAYGARATHACNGARGAYGARATHMGNGARTTY CARAAYYTNYTNCARAAYCAYTGYCAYGGNCARAARAAYGGNYTNAARTCNTCNYTNMGN AGYGCNYTNGAYMGNAARYTNGGN------ACNGAYGGNATGYTNAAYGGNATHTCNTCN GARGARGARAAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYGGNAARTAYCCNMGNGARTAYAAYCCNAARGTNCAYGGN CCNTAYATGCCNGGNMGNTTYTAYGGNAARCCNGAYACNCCNYTNGGNCARGTNAARYTN GGNGARYTNGGNACNTGGTTYGCNMGNMGNAAYAARAGYCCNCARGCNGCNTGGGGNGCN GTNCAYMGNACNTAYTGGMGNTGGGCNGCNAAYAAYYTNCAYGTNMGNAAYAGYGGNTTY GTNCCNTTYGGNCARGCNGCNATGGTNATGTCNATHGCNTTYTTYTTYYTNYTNTAYGGN GARMGNAGY--------------------------------------------------- ---------------------------------YTNAARTCNACNATHTCNGGNYTNGGN GAYGAYYTNAAYAARTAYAARCAYYTNCARGAYGARAGYACNGCNGAYATHCAYATGAAR AAYGARCAYYTNCARGARCARGARGCNATHYTNTCNGARACNMGNCARCARYTNGTNATH GCNGARAGYCARYTNGARGTNGCNAAYGARAARACNGAYGCNYTNGARTCNTCNGTNGCN GGNYTNAARCARAARTAYAGYCARGCNAGYACNCARATHGGNCAYYTNGARGCNACNGTN AAYACNYTNCARGAYAARYTNACNGARAGYMGNAGYMGNGARATHGAYAARGARCARACN GTNGARCARYTNMGNGCNGARYTNGARGGNYTNGAYMGNGCNTAYTCNGARAGYAARGAR GARYTNAGYAARTGYGARGAYATGATHCAYCARYTNACNACNGARYTNGAYTCNTCNCAR AARGARATHTGYTCNTCNCAYAARMGNATHAARGAYYTNGARGAYACNGGNMGNGARATH MGNGARCARATGCARAAYGCNCARCAYCARGCNYTNCARAAYGAYGARMGNGCNCAYAAY TTYGARAAYAARYTNYTNTCNTAYCARGGNGARCAYAGYCAYTCNGAYMGNGARTTYYTN CARAARGARGARCARATHAAYTCNYTNGARTAYCARYTNGARGARACNAARAGYGAYGTN GARATGMGNCARTCNACNATHGAYCARATGAARTCNGAYYTNGCNATHTCNCARTCNGAY YTNACNCARGCNMGNGARGAYAARAGYGCNGCNYTNAARGARATHGAYMGNYTNGARCAR CAYAGYCARCARYTNCARYTNAAYYTNGCNTCNGCNCAYCARMGNCAYAARAGYGARACN TGYMGNTTYGARGARCARGTNTCNTCNYTNGARMGNCARGTNTCNGARACNCARGCNTCN YTNMGNAAYGCNGARTGYGARATHAAYAAYAARGARGARCARATHAARMGNAAYGARGCN GARATHGCNTCNTGYMGNGAYGAYATHMGNAGYAARGTNGARGARATHGARMGNYTNGAR MGNTCNYTNCAYGARATHMGNYTNGARATGAAYCARACNAAYGTNCARTGYAARCARYTN GARAAYGTNATHGCNGARYTNAARTCNGAYGGNGARAAYYTNMGNAARGAYYTNAAYGAR TCNMGNATGCARTAYAARGAYTGYGCNCARGARYTNGCNCAYCAYGARGARAARYTNAAY YTNATGGARCAYAGYYTNCARTCNACNCARGAYCARYTNAGYCARMGNGTNACNGARATH GTNMGNCAYGARCARAAYACNMGNAARYTNCARGCNGARYTNAARGCNATHAARGARMGN GCNGARGCNTAYGARGARGARATGGARGARCARAARGTNATGATHGAYAARYTNMGNAAR GAYYTNGTNYTNTCNAARGARGARTAYCAYGCNTCNGTNCARGARGGNATHGCNTAYAAR CARCARGCNCAYAARAAYGARYTNGARYTNAAYGGNAGYMGNGARCARGARAARATGYTN TCNGAYCARGTNGARCARCARGARCARATHYTNAAYCARYTNCARACNGARYTNMGNGCN GARMGNGARMGNCAYGGNGAYACNGTNCARCARYTNAGYGCNAGYAARAARAAYGGNYTN GAYATHCARGCNGAYYTNGARGCNATGCARAARCARGCNMGNGARYTNCARGAYMGNGTN AARGCNMGNGARGARCARATGGTNMGNYTNMGNCAYGARATHGAYAAYATGCAYCARAAR AAYMGNGARAGYAAYGARYTNATGGCNGARAARGARGGNCARYTNMGNYTNGCNGARATG AAYYTNCARACNGCNCARAARCARGCNAARCAYCAYGCNCARGARATHGCNMGNTAYGAR GAYACNYTNGCNCARYTNCARACNGAYCARGARAARYTNCARGARCARTAYMGNAAYTCN TCNTCNAAYYTNATGGARGCNGAYAGYAARGTNCAYGARYTNAARGTNCARYTNACNACN YTNCARGGNCAYCAYAARGARGCNATGGAYCARYTNACNGAYAARGCNMGNCARYTNGCN GCNATHAARACNGARGCNGCNAARATGGCNCARCARAAYAAYTCNATGAARGAYGARATH ATGATHTAYGAYGARAARGTNMGNAARYTNCARCARGARYTNMGNAARTCNCARGARYTN AAYAARGCNACNGARGARGARYTNCARCAYTTYGARGARMGNTAYACNAGYYTNCARGTN GAYYTNGTNTCNAGYCARGARAARCARAARCAYTCNYTNCARGARYTNTCNTCNAARGAR GARGARAAYGTNGTNGTNAARGTNGARYTNAGYTCNYTNCARGARAARTAYAARGCNGTN AAYGAYGARGTNCAYAARYTNACNAGYGARYTNGARYTNACNAARCARAAYTAYMGNAGY GCNACNGARGARATHTCNGGNYTNMGNGTNGCNYTNGARGARTCNMGNGCNAAYGGNGAY MGNYTNCAYMGNGARAGYGARYTNGTNGTNCAYAAYGTNAAYACNTGGGTNCARGARCAR AARNNNGCNAAYGARAARYTNGGNAAYAARATHMGNGARCARAGYAARTCNATHATGGCN YTNACNTCNGARAARGARACNYTNYTNGARCARGTNGCNAARYTNCARAARAAYTAYAGY AARACNMGNACNGARYTNGARGAYAARACNATHGARGGNGARAARYTNMGNGCNYTNCAR TCNCAYTCNGCNCAYCARCARGTNGTNYTNAAYCARYTNAARAGYMGNYTNGARGARCAY GARYTNGAYAARGAYGCNGAYYTNAARACNAARGTNGCNACNATHGARGAYYTNCAYCAY MGNYTNAARTCNAAYATHGARAGYATHCAYCARYTNAAYCARCARYTNAGYACNYTNCAR AARGAYAAYATHMGNYTNMGNAGYGARYTNGAYMGNGARATHTCNACNMGNCARAGYYTN GARATGCARATHCARGGNAARGAYCARYTNGTNGARTCNYTNMGNTCNCARYTNGAYTCN AAYTCNTAYAARCARYTNYTNGARAARGTNGARCAYTAYAARGAYCCNGARAARYTNATH MGNTCNGGNYTNAGYAARACNGCNGARGARACNGGNGTNGTNGAYCCNCAYAAYYTNGAY AARTCNTAYTGGGTNCARMGNGTNGGNGARGARAARYTNTCNATHCARYTNCARCARAGY AGYGARTAYTGGTCNGAYAARGTNMGNGAYYTNTCNGARCARYTNGARAARTCNMGNTCN AAYTCNACNGCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AGYCAYGAYTAYCAYTAYGTNTAYCAYCAYCAYCAYCAYMGNCARCCNCCNCARYTNATG AARCCNGARCCNYTNGCNGARMGNTAYCAYCARACNCAYAGYGCNGCNACNTCNMGNGAR GGNGGNGGNTTYYTNMGNAARTCNTTYGCNTCNTTYMGNGCNATGMGNAARGCNGGNAGY MGNAGYAARGARAARGAYAGYMGNACNAAYCCNCARACNGAYGARAAYGARAARTGYYTN GTNTGYCCNTAYCCNCAR---TCNCARAGYYTNGAYAARAAYGGNTCNCAYAARAARACN TCNAARCARTCNAARMGNGAYYTNAARAAYYTNATGAARTCNAARAARAAYAARCAYAAY CAYCCNGTNCARGARGAYGCNTCNTGGTGYTCNGAYAGYGAYGCNCARAAY------ACN CAYCAYYTNCAYGGNTTYGAYAAYGTNCCNTAY---ACNACNATGAAYACNTTYCCNGTN MGNGARTGYTCNATGGARAGYTCNATHTCNCAYGTNGCNGGNTCNMGNGAR---MGNGTN GAYCARCARTAYTTYGARACNGCNTCNYTNTCNGGNTAYGAYTCNGAYGTNACNAARAAY MGNACNGGNMGNTCNMGNTCNMGNATHAARACNAAYCCNTGGYTNCCNTCNCCNCARCCN TCNYTNACNATGGGNMGNMGNATGGARAARMGNCARTCNMGNGAYAAYAAYGAYGAYTTY ATG--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYYTNMGNATHAAYCAYTTYGAYATHGGNGAR ACNATHGCNCARMGNMGNMGNMGNGCNGGNGTNTTYAARAAYCARTCNGGNCCNCCNCCN GARMGNMGNAGYACNATHAGYAGY---ATG---ACNAGYAGYTAYCARGTNACNMGNATG MGNAAYYTNTCNGGNGGNAGYAGYGGNAGYGCNGCNAGYGGNAGYAGYAGYGARGGNTCN GTNCARYTNGAYAAYCARTAYTCNTCNACNGAYAAYCAYYTNTAYTTYACNAAYTCNTCN TCNCCNTCNTCNTCNTCNTCNTCNTCNGCNGTNCCNAARCAYAAYGARGAYTCNGCNTCN ACNTCNCAYMGNAARYTNGAYMGNAGYYTNAGYGAYAGYGAYAGYGAYMGN--------- ---------------------------TCNGGNAGYMGNTAYAARACNGARYTNTGYMGN CCNTTYGARGARAGYGGNACNTGYAARTAYGGNGAYAARTGYCARTTYGCNCAYGGNTCN CAYGARYTNMGNAAYYTNGCNMGNCAYCCNAARTAYAARACNGARYTNTGYMGNACNTTY CAYACNATHGGNTTYTGYCCNTAYGGNCCNMGNTGYCAYTTYATHCAYGARGAYGAYAAR GGNGARACNACN------ACNCCNAARYTNGGN--------------------------- ---AGYAGYGGNAGYGGNAGYAGYAGYCCNTCNYTNAGYCCN------ACNYTNAAYGAY CARAAYAAYTTYTCNTAYTCNTCNGARTCNTCN---CARYTNAAYATHATHAAYGCNCAR ATHAAYAAY------TCNYTNACNGTNAAYATHAAYTGY------------GGNAAYGAY GARYTNCARTCNYTNGARCAYCAR---TTYAAYTCNGCNYTNAAYTTYAAYMGNAAY--- ------------------------------------------TGYAAYGARTCNTCNMGN AAYAAYAAYAARTCNGAYGARCARGAYATHTTYAGYTCNATHTCNGTNTTYAAYGCNGAY GARGTN---ATHGAYAAYGCNCCN------CCNAARCAYAAYTCNTAYTCNTCNTCNYTN TGYAAYCARAAYYTNGAYAAYTAYMGNGGNTAYGTNAGYTCNTCNCAYTTYTGGCCNTCN ------AAYATHTCNTCNCARGGNATHGGNCCNATHGAYCCNTAYAAYTAYTCNCCNACN GGNTCNACNGGNTCNACNAGYTCNTCNGGNTCNGAY---TCNAGYAGYGGNAGYGAYTGY AGYGGNAGYACNGARAGYYTNGTNAGYTCNGGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GGNATHGCNACNTTY TGGGCNCARCCNGARGAYGARMGNAAYTAYMGNAARYTNGARAARGGNAARATHGTNGTN TAYGCNACNTCNATGAGYGTNGTNMGNGARACNAGYGARMGNTGYAARTCNGTNMGNAAY ATHYTNCARAAYCAYATGGTNMGNTAYGARGARMGNGAYYTNTAYATGAGYMGNGARATH CARCARGARYTNAARCAYMGNYTNACNCARGAYGGNGTNGARGCNATHMGNYTNCCNCAY ATHTTYGCNGAYGGNYTNMGNATHGGNGGNGCNGGNGARYTNGARMGNYTNAAYGARGCN GGNGARYTNMGNGCNYTNYTNGARGGNTAYCARAARATHAAYGCNMGNTTYACNTGYGAR MGNTGYGGNGGNTAYMGNTTYGTNCCNTGYGARATHTGYCAYGGNAGYAARMGNTCNYTN ATHMGNAAYCAYTTYACNGARGAYTTYTTYGCNYTNMGNTGYATGCAYTGYGAYGAYAAY GGNYTNMGNMGNTGYGARYTNTGYAARGARCARCARGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GTNTCNAGY GTNGAYYTNMGNYTNMGNMGNTCNGGNMGNTTYGAYCARGARATHYTNATHAAYGTNCCN TCNGARGCNCARMGNYTNTCNATHYTNCARGTNYTNACNTCNGAYYTNACNYTNGCNTCN GAYGTNTCNTGYAARGCNYTNGCNCARATGACNCCNGGNTTYGTNGGNGCNGAYYTNMGN GGNYTNTTYGARGARGCNATHGCNCAYGCNCARGARCARGTNAARAARGAYYTNAAYGTN ------YTNAAYYTNGARGAYTTYTAYCAYGCNYTNCAYAARACNACNCCNTCNYTNAAR AARGGNACNGARTGYGTNGTNGAYYTNAARCCNGTNMGNTGGGTNGAYATHGGNAGYYTN GARGARATHAARGCNGARATHMGNCARTCNATHGARTGGCCNYTNAARTAYCCNGARATH YTNGARAAYATGGAYATHCCNCCNGCNAARGGNATHYTNYTNTAYGGNCCNCCNGGNTGY TGYAARACNACNYTNGTNMGNGCNGCNGCNACNTCNTGYCAYGTNTCNTTYYTNTCNYTN AGYGGNGCNCARGTNTAYTCNGCNTAYGTNGGNGARTCNGARMGNYTNATHTCNCARGCN TTYCARAARGCNMGNGCNYTNGCNCCNTCNATHYTNTTYTTYGAYGARATHGARTCNYTN GTNGGNAARMGNGTNGCNAAYGTNGGNCAYAAYMGNGTNCARGARMGNATHYTNTCNACN ATGYTNAAYGARATGGAYGGNGTNGGNAAYAARATGGAYTTYAARATGGAY---TCNMGN TCNCAYGAYMGN------------------------------ATHGARATGCARAARATH GARCARGARAAYGAYGGNYTNTGYCCNTCNACNACNMGNTGYAAYAGY------AAYAAR AAYAAYYTNAARGTNATHGTNGTNGGNGCNACNAAYMGNCCNGAYATGYTNGAYTCNGCN ATHYTNMGNCCNGGNMGNYTNGAYAARCAYATHTAYGTNCCNCCNCCNGAYAARGARGCN MGNAARGCNATHYTNGARATHTAYTCNTCNAARATGTCNTGYAAYGAYGTNGAYATHAGY GTNYTNGCNGAYMGNACNGARYTNTTYAGYGGNGCNGAYYTNAARAAYYTNTGYAARGAR GCNGGNYTNGARGCNGTNMGNMGNCARYTNACNAGYAGYAARTCNATHAAYCCNYTNATH GTNACNAAYGAYCAYTTYYTNCARGCNYTNGAYAARGTNAARCCNTCNYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GARGAYGAYCARACN GARGTNYTNAAYACNATHGCNTCNYTNCAYATHAAYYTNATHCARAARATGAARAARAGY MGNCAYYTNTCNCCNGAYCARATHGARGAYTAYATGAAYCARGCNMGNYTNGAYYTNCAR AAYGTNAARYTNAARATGGAYTCNGAYAARGARGTNCARGARGARGARYTNTTYAARAAR YTNAGYAAYCARAARMGNAARACNYTNGCNGARAARATHGCNGARCAYCARAARCARYTN CARGAYTAYATHAAYMGNAGYAARGCNCARCARACNGARGGNCCNGTNGAYCCNGTNTCN TAYGTNGAYGGNYTNGTNGAYYTNAARTCNMGNCARMGNAARGARYTNAAYACNYTNGAR AAYCARATHGAYMGNGAYCAYGCNCARCARYTNGARGARYTNMGNGAYGARGTNTCNAAR AAYGCNYTNAARGARYTNGARGGNGTNCARGGNGARYTNGTNAARAAYYTNAARGARGAY GGNGTNMGNGAYGAYGCNATHGARAARATGYTNCARAARCAYGARCARACNGTNGAYGAY YTNMGNAAYAARCARCARAAYAAYMGNMGNAAYCARGARGCNAARYTNAARGAYGARYTN GCNMGNMGNAARMGNGARTGGGARCARAARAARGARCARGARAARAARGARCARGARGAR YTNMGNGARCAYGARGCNGARATHGTNGAYAARYTNYTNAGYAGYCARGTNTCNATHTCN GARACNGARAARGAYMGNATHATGAARGARCAYGARAARCARATGGTNAARYTNGARAAY AGYYTNACNYTNTCNAARYTNAARCARMGNMGNATGYTNGARGARAARATHGCNCARAAR MGNGCNMGNCARATGGARGARYTNGARAARAARCARAGYACNGARATHCARAARCARMGN MGNATHGCNGARAAYAAYGGNGARGAYGARGARGAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GCN GARATHATHGAYATHTAYCCNAAYGCNAARAAYCAYYTNATHYTNYTNAARAAYYTNCAY ATHGGNCARAGYTAYTCNGCNTTYATHGTNTGYGAYMGNACNACNAARACNAAYATHGTN GAYTTYATHTTYGGNAARTCNTGYAAYAAYYTNAGYGARCAYGARAAYCAYAAYGARAAY TCNMGNAAYGARAAYGCNAARGTNGARGTNYTNAARTCN------------GARAARTTY AGYACNGTNGGNYTNYTNAGYGCNGTNATHTTYTCNGTNATHGGNACNYTNYTNATHTTY GTNGTNGTNTAYTAYACNTGGAARAARTAYCARCAYMGNCARMGNGTNYTNMGNATHTTY MGNCARGAYCARAAYGAYCCNTTYCARGCNYTNTAYAGYCCNGCNCARGAYGTNTAYTCN TCNYTNTTYGGNTCNGCNGAYATHMGNACNTGYMGNTCNTAYGARGCNATGGAYAARYTN GCNAGYYTNACNCAYCAYTCNGAYATHMGNYTNTGYGCNTCNAGYCCNGGNATHTAYATH CAYCAYTCNMGN------AGYCCNGTNMGNTCNGCNAAYGCNAGYAGYGAYGAYGGNAGY GAYYTNYTNACNGCNGCNAARGCNTCNMGNATGGTNGAYGTNYTNACNGARGARAAYGGN AGYYTNMGNGARGARYTNGCNATHGCNGCNATHAARGTNTCNMGNYTNTCNAARTTYGAR ATGGARGTNCARAARATGCAYGARGCNCAYCARGCNYTNYTNGARTCNCAYCARAARMGN GARACNYTNTGGYTNGCNATGMGNMGNAARYTNGARGARMGNATHCARAGYYTNGARGCN ACNGCNGCNCCNAAYAGYYTNGARGAYTCNGAYATHTCNAAYGTNGCNTCNYTNACNGAY TCNGAYYTNMGNTCNMGNYTNYTNGARAARGARTCNATHATHACNMGNYTNYTNTCNCAR AAYCARGARYTNATGGCNAGYMGNAARCARYTNGARACNGARAAYATHCARYTNAAYGTN ACNYTNGCNGARCARACNGCNCAYGTNGARATHGTNGARAARGTNYTNGTNAAYTGYCAR GCNAARTTYYTNATGGGNAAYGARGARAGYCARAARAARATG------------------ ------------------------------------------YTNGGNGARGTNTCNACN MGNAGYTGYAGYCCNTTYYTNMGNTCNAGYAGYGARATGATHGAYAARCARGAYTCNGGN GTNGAYTCNGARYTNMGNGARGARAGYMGNGARAAYYTNACNGGNTGGAARYTNGGNGAY ---------------------------GARATHTCNGGNYTNAARCARACNTAYYTNAAR GAYTCNAAR---GCNGCNATHTGYATHGAYGARGCNTCNCARCCNYTNAARGARGTNMGN YTNGCNGCNYTNGARAARAAYGCNTCNGAYGTNGARAARYTNATHGAYGARGCNAARACN GARAARYTNAARCAYATGGARGARYTNCAYGARAGYAAYAARAARATGGCNGARYTNGAR GCNAARGTNAARCARYTNCARACNCARYTNGTNGARAARGARGCNATGGTNAARGTNTTY CARMGNTCNCCNTAYTCNYTNCCNMGNTCNTCNTCNYTNCAYGCNYTNTGYCAYTCNCCN YTNCAYTCNCCNMGNCCNTCNYTNATHGCNACNCARGCNGTNGARGGNATHGGNTCNTCN TTYATGTCNCCNGTNACNGGNGGNAGYMGNGARTAYTCNTCNATHMGNCAYYTNAARTCN GGNAGYACNAGYGCNATHGARAARTGYMGNAARYTNTCNATGGARGARGAYYTNYTNTCN AARGTNCARAGYYTNAAYTGYCARAGYAARGAYGAYTCNACNGARGARGTNMGNYTNTGG CAYGTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNACNATGTTYGAYGAYGTNAGYGGNTTYGGNGCNYTNCARMGNMGNTGGTGY GTNYTNTCNAGYAAYAARYTNTGYGTNTGGAARTAYCCNGAYGAYGARACNMGNAARGAY CCNATGACNATHATHGAYYTNAAYMGNTGYATHACNGARAARGTNGGNYTNGTNCCNMGN GAYATHTGYGCNMGNCCNAAYACNTTYGARYTNGTNACNGTNMGNCARCARYTNAARGGN GARCAYGAYACNYTNATHTCNAARACN--------------------------------- ------------------------------------------------------------ ------------------------------------------GAYTTYGGNTCNTCNATH YTNGGNACNCARGARTAYTGGGARGARACNTAYGTNAARGARYTNCARAAYTTYGARGAR YTNGGNGAYGTNGGNGARATHTGGTTYGGNGARGAYACNCARGARMGNATGGTNMGNTGG YTNTGYAAR---AARTCNGTNTCNAARGCNTCNAARATHATHGAYYTNGGNTGYGGNAAY GGNATGYTNYTNYTNGCNYTNMGNCARGARGGNTTYACNGAYYTNACNGGNGTNGAYTAY TCNGAYCAYTCNGTNAARYTNGCNMGNAARGTNTGYGARGCNGARGARGTNAAYGAYATH MGNTTYGARGTNTGYGAYATHYTN---TCNTCNTCNATGGARTCNAGYMGNCAYAARAGY YTNTAYGAYATHTGYYTNGAYAARGGNACNTAYGAYGCNATHAGYYTNAARGAYACNACN GAYCCNACNGAYMGNCARAARTAYATHGAYCAYGTNAAYTCNATGYTNAARCCNAARGGN CARYTNYTNATHACNTCNTGYAAYTGGACNAARGAYGARYTNACNCARCAYTTYTGYAAR GCNTTYCAYYTNACNGAYGARATHCCNGCNCCNAARTTYACNTTYGGNGGNAARACNGGN CARAARGTNACNTCNYTNATHTTYACNMGN---------------GTNTTYCCNGARGAY GGNATHTAYGGNTGGMGNTTYTCNACNMGNAARTCNGTNYTNCCNTTYYTNGARACNATH CCNGAYCCNAARGTNACNACNTGGAGYCCNTGYTCNGAYCCNGARMGNTAYCCNGAYACN GARGTNCARCAYGCNYTNAGYTGYATGGCNAARGARAAYGGNYTNTAYGTNGTNGCNAAY ATGGGNGAYYTNYTNCCNTGYGAYGGNAARGARGAYACNAARTGYCCNAARGAYMGNGGN TAYCARTAYAAYACNGAYGTNGCNTAYGAYCCNGARGGNACNYTNGTNGCNAARTAYCAY AARGTNAAYYTNTAYTTYGARCCNCARTTYAAYMGNCCNGARCCNCARGTNGTNTAYTTY GAYACNCCNTTYGGNMGNTTYGGNATGYTNGTNTGYTTYGAYYTNYTNTTYAGYACNCCN GCNMGNCCNATGYTNAARGARCAYAAYATHGCNAAYATHGCNTAYCCNACNGCNTGGATG GAYGCNYTNCCNATGYTNTCNGCNATHGGNTAYCAYTCNTCNTTYGCNMGNGGNACNGGN GTNAAYTTYYTNGCNGCNAAYATHCAYATGCCNTCNAARMGNYTNCARGGNAGYGGNATH TAYACNCCNAARGGNGTNAARAARTAYTAYTAYAAYAAYGAYCCNAAYTCNCCNGGNAAR YTNYTNGTNTCNACNYTNGGNGTNYTNGARTCN--------------------------- ---------------------------------------------------AAYGGNGAY GTNGARGAYATGAAYATHCARAAYAARCAYATHATHAAYCCN---------YTNAAYMGN ACNGGNCARGARTTYTAYTCNAGY------------------------------------ YTNYTNCAYGAYCARTAYAARTTYMGNATGYTNGAYGGNGCNACNGGNAAYATHAGYATH TGYCAYAAYAAYYTNTGYTGYTCNYTNGAYTAYGARGAYGGNGGNMGNTCNGAR---CAR GARYTNTTYGCNYTNGGNGCNTTYGAYGGNYTNCAYACNTAYCAYGGNCARTAYTAYYTN CARACNTGYAAYYTNGTNAARTGYGGN---AAYAAYCARGAYMGNYTNTCNTGYGGNCAY TAYACNTTYGAYACNAAYACNAARTTYAGYTTYYTNTCNYTNACNGGNACNTTYCARACN GARTTYGTNTAYCCNCARGTNATHATGAAYAARGAYMGNCARYTNMGNGTNGGNGAYGAR TCNTCNTGGAGYTTYAARGAYAAYATH---YTNACNTCNGARGGNGGNYTNGAYGAYCCN YTNYTNGCNGCNACNYTNYTNGGNMGNTAYTAYAAYYTNGAYAGYGAYTCNGGNAGYGAR GAYGTNAGYATGTCNTAYGAYGGNCCNGGNGGNMGNAARATGAAYGGNCARATHGAYGAY GAYGTNTGYMGNGAYTAYATGMGNAAYGTNTGYACNMGNGGNAARAAYTGYMGNTAYMGN CAYCCNGTNGTNGARGARCAYCCNGAYCCNCCNCCNMGNMGNGAYATHACNTTYTGYCAY GAYTAYCARAAYAAYGGNTGYACNMGNGGNAAYTGY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CCNMGNGCNCCNCCNGGNGCNGCNACNYTNTCN------------ GCNAARCARCCNATHGTNYTNTCNCARCARACNGCNTCNGGNGCNYTNAARMGNMGNCAR CCNGTNGCNCARAAYGTNGTNAGYGGNCCNYTNMGNYTNGGNAARGGNGGNGGNCCNGGN YTNCARGTNGGNATHGGNGARGTNTCNCCNCCNAARMGNGCNAAR------CCNGGNGTN CAYGCNTCNCARCCNATHGARATHYTNGAY---GARGAYAAYTCNAARTTYGTNAGYCCN ATHCARGGNTTYMGNGTNGTNGTNACNAAYYTNTTYTCNGGNGTNACNCARGAYGAYATH ATHGARYTNTTYGGNGTNGTNGGNCCNYTNAARAARGCNMGNYTNYTNAARGCNGGNTCN GCNGARGTNGTNTAYACNACNMGNGARGAYGCNTCNAARGCNGTNCARAARTAYCAYGGN MGNGARYTNGAYGGNCARCCNATGTAYGTNAARATGACNACNCCNGCNACNGCNGTNGTN AARATGCCNYTNGGNCAY---GAYCCNGAYATHACNGGNGARGCNYTNMGNYTNTAYAAR AARCCNAGYAGYYTNGGNGCNYTNCCNGARGGNCCNATHGARGTNCCNACNATHCAYMGN GCNYTNTTYAARGTNGGNCCNCCNGCNCCNAAYAARTCNGTNAARTTYACNGTNAARATH AAYTAYATHGCNGGNYTNATHCARYTNYTNMGNGAYTGYATHYTNTGYCAYMGNTGGCAR GAYGCNYTNAARATHGTNGARACNYTNGCNAARGARGGNGAYAARGTNGCNGTNATHTCN TGGAARGTNGGNATGGCNTCNYTNATHYTNGARMGNCARTCNCAYCCNYTNGARYTNTGY GTNMGNTAYYTNTGYMGNYTNCCNAGYYTNTCNTCNTGYGARGTNYTNTTYGAYTAYYTN YTNTGYYTNATHACNGTNGGNGARYTNGARMGNGCNAARGAYYTNCARAARGAYTTYGGN GARYTNGARGARMGNMGNCAR------ACNACNMGNATGGAYTAYYTNAARATHATHTTY CARTCNTAYATHGGNYTNATHTAYTAYYTNYTNTGGAARGCNGARATHGCNGARAARGAY ACNGAYGAYATHGARACNGAYTTYATHTCNTCNCARYTNAGYCARGGNAGYGTNCAYCAR ACNTCNGAYGCNAARGCNGARAAYGCNGTNTAYAAYATGTCNTAYATHMGNGGNGTNCCN GGNGTNTGGGAYATHTTYATHGTNAARGTNGTNGARATHCAYGARTTYAARGAYGAYYTN GARAAYGCNMGNTCNTGGYTNAARGAYTAYAARCARCARAAYCARGAYAAYYTNAAYGCN CAYMGNTAYTGYTAYMGNTTYGARATGMGNCAYAAYGGNGARAAYGAYGTNAARYTNGAR AGYYTNAARAAYATHATHMGNYTNGAYCCNAGYAAYCCNYTNGCNTTYGAYYTNTAYAAR CAYYTNGARCCNTCNGAYCCNGARGCNATHTCNGTNYTNTTYGAYTAYYTNGAYTTYGAY CAYTGYAARAAYGAYYTNCARGCNTGGACNYTNYTNAARAARCAYYTNACNGAYGARTAY MGNACNTCNGTNTCNTAYCARGCNGTNGARAARTGYTGGATGACNMGNMGNGAYTGGTGG CCN--------------------------------------------------------- ---AARAARTCNCCNATHTGYTCNACNTGYMGNGARATHGTNGARAAYTTYCAYAARGGN YTNTCNGARACNGARAARTCNAAYTAYGGNGGNGGNAAYACNAAYTGGGARGARAARTCN YTNGGNTCNTAYGCNACNAGYGARGTNMGNYTNGTNGARATHATHGARAAYYTNTGYAAR GAYAARTCNAARGARTGYCAYACNATGYTNGARGARCAYGARGAYYTNGTNGARAGYTTY TGGTTYAARGARTTYGCNAARMGNTCNGGNAARGAYTTYCAYACNTTYTTYTGYATHGAR ACNATHMGNGCNTGYTGYCCNAAYAAYACNTTYGGNAARGAYTGYCARCCNTGYCCNGGN GGNGTNGAYMGNCCNTGYYTNGGNAAYGGNAARTGYTCNGGNGARGGNACNMGNAGYGGN ACNGGNAARTGYMGNTGYAAYTCNGGNTAYATGGGNGAYYTNTGYGAYGAYTGYAARGAY GGNTAYTAYGARGAYAGYAARAAYGARACNCAYGTNGTNTGYAARGTNTGYCAYATHTCN TGYAARGGNAGYTGYTCNGGNGARGGNCCNAARGCNTGYGAYGTNTGYAARGAYGGNTAY YTNTCNGAYCCNGAYCAYGGNTGYAARGAYATHGAYGARTGYYTNGARGARCCNTGYGAY GAYGAYCARTAYTGYACNAAYACNYTNGGNTCNCAYTCNTGYTTYAGYTGYAAYGCNGCN TGYGCNTCNTGYACNGGNTCNGGNCCNGAYAARTGYAAYGARTGYAAYAARGGNTAYATH AARTTYGAYAAYGGNAAR---TGYGARGAYCARGAYGARTGYAGYYTNGAYCCNAGYYTN TGYACNAARTCNAAYGARGARTGYGTNAAYACNCCNGGNAAYTAYGARTGYATHTGYTCN TCNGGNTAYGARTAYAAYACNGAYAARGARTGYGTNAARACNGCNAARGAR--------- ------------------------------------------------ATGGGNGGNAGY GARAGYAARMGNMGNATHGTNGTNGARGAYGTNAAYGGNGARGGNGTNGTNCARGTNACN CAR---GCNGTNGTNMGNMGNGTNAAYGGNCARCCNGAYCCNCCNGTNCARAARTCNCCN TCNTCNAAYAAYGAYTAYMGNGTNCCNCCN------------------------------ ---------AARGAYACNACNAARGARATHGARGAYTTYTAYATGGARAARYTNAAYGAY YTNCARAARMGNAGYCARGARYTNCARGAYCAYTCNAAYGARCARTTYTCNAAYGCNGTN AARGARGTNGARCARAARTTYATGAARTAYACNTCNTCNCCNGTNTGYCARGAYYTNCAR ACNAARGTNYTNGARTGYTAYCARGCNAAYCCNAAYTCNGTNYTNGAYTGYTCNTCNATH GTNAAYGCNTTYAGYACNTGYGTNGAYMGNGCNMGNATGACNGTNTCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARGCNGAYACNATHAGYMGNATHAGYAARYTN TGYGTNGARAGYAAYYTNYTNTCNGARGCNAAYGAYATGATGAARCARYTNACNGTNYTN CAYTCNAGYCARGGNGARGTNGARAARGARYTNCARTCNATGGTNGARMGNTCNAAYYTN YTNYTNAARATGGGNMGNGCNCARGARGCNGARGARGTNGCNGAYGARTGYYTNAARGTN YTNGAYGARAAYACNCCNTCNYTNACNTTYGCNAARATGTAYAGYGAYYTNTCNGTNGCN TAYACNCARATHYTNYTNTAYGARAARGCNGTNCARTGYAGYGARAARGCNYTNCCNYTN GTNGARGAYCCNAGYGGNGAYCCNMGNYTNGCNTCNGTNATHTAYCARAAYYTNGGNGCN ATHTAYAAYTAYATGGGNMGNTTYGARGAYGCNGTNAAYTAYCAYGARAARGCNTGYCAR ACNTTYGCNAARYTNGGNATGMGNGCNAAYCARGGNCAYTGYTTYACNAAYATGGGNTAY GCNTAYAGYCARYTNAARGAYATGGGNAARGCNGGNGARTGYTTYYTNCAYGGNYTNCAR GCNGCNMGNGAYTGYGGNGAYMGNAARACNGARTGGCARAAYYTNGARGCNYTNGCNAGY GTNGCNTTYCAYAARAARTCNTTYAARAARTCNGARCARTAYTAYCARCARGCNATHGCN GTNYTNTCNCARTCNCCNGARACNGCNGAYCCNTCNGTNCAYGARMGNYTNATHACNAAR YTNAARAGYATHATHAARGCNCARGCNCCNCCNMGNCCNGTNTCNCCNGTNAARAARAAY ATGGAYMGNYTNGTNMGNMGN---------GCNAGYAGYAARGCNGARAAYGTNAAYTAY AARGAYYTNCARTCNYTNGCNTCNCAYATGAAYTCNGGNGAYATHMGNGTNATHMGNAAR GGNAGYCARGTNMGNTAYYTNAARGTNMGNMGNTCNGGNACNYTNCARAARTTYCARAAR GTNGCNYTNGGNYTNGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GAYGAYAGYGAYTCNGAYGARGAYAAYATHYTNGCNGAYGAYMGNTTYAGY AAYMGNATHAAYCARGCNACNAARYTNGGNTTYTCNGARGARCARGTNATHAARGTNYTN AARMGNYTNGGNGTNAAYTCNAAYATGGAYGAYATGATGMGNGARYTN------------ ------------------GTNTCNGAYCCNCAYGGNGGNAAYACNGARGAYGGN------ ATGATGMGNYTNGARAAYYTNTCN---------------TCNAARGARGARGAYAAYGAY GAYAAYGAYAGYTTYGAYGTNAAYGAYAGYTCNAAYYTNMGNCAYATHATHATHGAYGGN AGYAAYGTNGCNATGAGYCAYGGNCARAARGTNTTYTCNTGYATGGGNATHAARATHGTN GTNGAYTGGTTYAARAAYMGNGGNCAYAARAAYATHACNGCNTTYGTNCCNCARTGGMGN AARGARGCNTCNMGNCCNGAYGCNCCNATHACNAAYCARGARATHYTNACNGARNNNGAR ACNGARAARATHGTNGTNTTYACNCCNTCNMGNMGNGTNGGNGGNACNMGNATHGTNTGY TAYGAYGAYMGNTTYGTNYTNCARYTNGCNGTNCARAAYAAYGGNATHGTNGTNTCNAAY GAYGTNTAYMGNGAYYTNGTNMGNGARMGNGAYGAYTTYAARGTNGTNGTNGARAARMGN YTNYTNATGTAYTCNTTYGTNCARGAYATGTTYATGCCNCCNGARGAYCCNYTNGGNMGN CARGGNCCNTCNYTNGAYAAYTTYYTNMGNATHMGNCCNTCNGARCCNAARAAYAARCCN CARAAYTGYCCNTAYGGNAARAARTGYACNTAYGGNAAYAARTGYMGNTTYTAYCAYCCN GARMGNMGNTAYGCNCCNCARAARATGGTNGCNGARAARYTNAARGARAAYGCNGARYTN AARATGAARTCNAGYAARGARCCNCCNACNGAYAARGCNAARCARCCNAARCARAARYTN GTNMGNACNGTNTCNYTNGTNCCNCARGAR------YTNGTNAAYAGYTTYTCNGAYGGN AARACNAARAARCCNCCNYTNCAYCAYTCNAARTCNATGGTNTAYCCNAGYAGYTAYYTN AAYGAYYTNMGNYTNAARATGGARCARGCNGARTCNGCNGCNTTYCARCARACNCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------MGNGAYGTNTGYGCNGAYATGYTNACNTCNATHCARAAR YTNMGNGARYTNGAYCCNGAYAAYCCNAAYATGAARAARATHYTNGARATGCARAAYCAR YTNAAYGCNYTNCARAGYTCNYTNGGNAARTCNCARAGYTCNAAYGCNAAYAARGTNAGY GARCARGARACNGARTAYTCN--------------------------------------- MGNAARATHMGNYTNAGYTCNGCNGAYAARAARCARMGNGARATGAAYGAYYTNGARGAR AARTTYGARGCNGCNGARAARGCNGARMGNCARAARGARGARGARYTNAARCARAARMGN GARATGGARYTNCARAARAARAARGARTTYGAYGARAARAARAARATHYTNTGGGCNAAR AAYATHATHTCNGAYTTYAARAAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYMGN ATHYTNTGGATGTGGCAYGARGCNMGNMGNCARGARAARAARATHMGNGGNYTNATGGTN GAYYTNAARMGNMGNGCNGAYMGNMGNMGNGARTTYTAYGARAARATHAARCARGAYCCN ACNCARTTYYTNMGNATGTAYGGNMGNCCNGTNAARATHCAYYTNGAYCCNGCNGTNTCN ATGGCNGCNGARGGNCCNCARAGYATGATGGCNTGGCARGGNGAYAGYACNAAYATGATH GAYMGNTTYGAYGTNMGNGCNAAYYTNGAYTGYATHACNGARTAYAAYCCNAAYMGNTCN TCNAGYTCNACNATGAAYGCNCAYGARCARGARGARMGNYTNGCNAAYTAYGARMGNTAY MGNACNYTNGTNGARAAYGARGCNTCNGGNYTNTCNGARGARCARTGYYTNCAYCARATH TAYYTNGAYGARCAYTTYGGNACNATHAAYAARCCNAAYGARGARGARAARAARAARAAY GCNGAYAARAARGCNGCNATHGGNTAYGTNTAYGARGAYAGYACNCCNGTNGARAARAAR GARCCNAAYGARGAYAGYGARGARGARAGYGAYGARGAYYTNGAYATGGCNGAYYTNGAY GTNACNATHGAYGTNGAYTCNYTNACNCCNGAYATGTGYAARGARGTNAAYGCNGTNGCN GGNCARTAYGGNATGGTNGAYGAYGAYTTYGTNMGNYTNYTNMGNAARGAYAARGARGAR YTNGARGCNYTNAARGARGCNMGNCARYTNGARGARGCNAARGCNCARTTYTCNGGNMGN AARTCNMGNMGNGARMGNMGNGCNATHAAYGARAARMGNCARAAYCCNCARMGNTTYTGY MGNCCNAGYTAYGCNGCNMGNGAYAGYCCNAARTAYGARCCNTAYAARMGNCCNGGNTCN TCNTCNMGNTCNMGNTCNMGNTCNMGNTCNMGNTCNTCNGARMGNGCNGARGTNAARTTY ATHACNAGYTTYGGNGGNAAYGAYAGYGAYGAYGARGGNGGNGGNATHGTNCARGGNCCN TCNYTNCCNACNTCNACNACNCCNAAYGCNYTNTTYAGYCARAARAARATGTCNGARTCN TCNAARTGYGARACNCCNTGG--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AGYYTNGAYTAYAGYACNYTNMGNGARGCNGGNATHGCNTGYCAYCARATGMGN ACNTGYYTNAAYGAYGTNTCNMGNATHATHTCNYTNGCNYTNATHACNGARYTNCCNTCN YTNGGNGARCARGGNCARTTYTCNGAYCCN------------GARACNGARMGNYTNMGN GGNGARYTNTCNGARYTNCARTCNAARTAYAGYAAYYTNGARATGACNGTNAARGARCAR CARGGNAARYTNAAYGTNTCNAARCARMGNCARAARGAYTGGGARCAYTCNGTNTGYMGN CARGCNGTNATGAARAGYAARMGNTCNMGNAGYYTNTCNGARTCNTTYGAYGAYYTNAAY GTNATG---GGNAAR---------------GARCCNGGN------------GAYGTNGCN GAYTGYMGNGAYYTNGAYCAYGARAARYTNATGCAYTAYAAYAAYACNAARATHYTNAAY CCNGARYTNMGNGCNCARTAYGARCARATHAARMGNGCNTAYTCNGAYATHYTNTAYAAR TGGGGNYTNYTNAAYCARMGNGTNCARATHYTNAARCAYACNGTNTCNGTN---CARAGY AGYAARAARATHGARTTYTCNATHCCNTGYTCNAAYTGYTCNGAYACNGTNATGAAYGTN CARTGYAAYMGNTGYMGNTAYCCNTCNYTNAAYTGYGCNATHTGYCAYATHGGNGTNMGN GGNCCNGCNAAYATHTGYCARGCNTGYGGNCAYGGNGGNCAYTCNAGYCAYATGATGGAY TGGTTYMGNAGYTAYACNCARTGYCCNAGYGGNTGYGGNTGYAAYTGYATGCARGAR--- ------GTNCCNGCNAGYACNCCNAGYMGNAAYMGNAGYAAYAAYAARGCNGTNTCNTAY AAYAAYGGNTTYGAYTCNGAYAGYTCNATHACNTCNACNACNCAYACNCARTCNAARTAY GAYATHAARYTNYTNAARCARAAYCARMGNYTNYTNAGYGARGTNGARMGNYTNGTNGCN GAYATHCAYGCNGCNAAYCARAARAAYGCNACNYTNGTNAARGAYGCNGARAARGGNAAR ACNGTNGTNGARYTNGARGAYMGNTGYGCNGGNYTNGTNGCNGARAAYCARGCNCARGAY AARTCNYTNMGNGARGCNGARMGNCAYYTNGAYGARGGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AGYACN GCNYTNGCNGTNGTNYTNTAYCARGARGARAARYTNYTNCCNCAYGARAARAARAGYMGN AAYTTYAAYATHGGNGGNCAYAARTTYTCNATHGARCARGAYTGGCAYATHGGNGGNGTN GCNGCNGTNGTNTGGGAYGCNGCNYTNGTNYTNGGNGARTAYTTYGCNTCNAAYCCNCAY YTNATHGAYGGNAARCARATHYTNGARYTNGGNGCNGGNACNGGNYTNGCNGGNATGGTN GCNTCNTCNYTNGGNGCNGAYGTNATHGTNACNGARMGNGARGARGCNYTNACNTTYYTN GARAAYGCNATHTCNAGYAAYAARGCNGAYAARCAYTGGAARATHAARGCNGARGTNYTN GAYTGG------------------ACNCAYGAYACNGAYCCNCAYTTYGAYYTNGTNATH GGNGCNGAYATHGTNTAYATHGARAGYACNTTYTCNCAYYTNYTNAARACNATHAARTCN GTNGCNCCNTCNTCNAARACNAARATHYTNYTNTCNTGYMGNATHMGNTAYGARMGNGAY YTNAARTTYYTNAARATGYTNAARAARTTYTAYAAYGTNGARGARATHTTYTAYAAYGCN AARYTNGAYATHAARATHTTYTCNGCN---------AARTTYGTNACNCAYYTNGGNGGN TGYCAYTGYGGNGCNGTNMGNTTYTCNGTNAARGCNCCNGCNGTNGTNGAYGTNYTNGAY TGYAAYTGYAGYATHTGYACNAARAARCARAAYAARCAYTTYGTNGTNCCNAARTCNMGN TTYAARYTNYTNCARGGNGCNGAYTCNATHACNACNTAYACNTTYAAYACNCAYAARGCN AARCAYACNTTYTGYAARATHTGYGGNGTNCARAGYTTYTAYACNCCNMGNTCNAAYACN GAYGGNTAYGGNATHATGCCNCAYTGYYTNGAYCCNGGNACNYTNMGNTCNACNACNACN ACNCCNTTYGAYGGNATGCARTGGGARAARTCNATHGARACNTCNAAYGTNMGNGARMGN TCNAAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GAYAGYGCNAGY TTYGARGAYACNMGNTGYAARTGYGTNTGYTCNAARACNAARGAYACNAGYGGNAARGAR TCNMGNACNGTNTAYMGNAAYACNACNMGNAGYGARCARTGYGAYTGYAAYCAYGTNGTN AARCCNYTNTCNCCNAAYYTNCCNTGYTCNYTNTGYCARTGYMGNACNGARACNMGNAAY ACNACNACNATHAARGTNGTNGTNATHTTYATHATHTGYGTNGTNTCNYTNYTNTTYGTN TAYATGYTNTTYYTNYTNTGYYTNGAYCCNYTNYTNCARAARMGNCCNGCNAARTCNTAY CARCARCAYACNAAYGARGARGTNAAYYTNGARGAYYTNTCN------CARMGNGGNGAR GAYCARGCNAGYTCNTCNCARTCNCARYTNACNGAYTCN---------YTNTCNGCNMGN CARMGNTCNYTNYTNAAYATHGTNACNAARGARCARAARAARTGGAARGGNACNGTNCAR GARCARMGNMGNAAYATHTAYGAYMGNCAYTCNATGYTNAAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAY CAYGARYTNTAYAAYGTNAARMGNGAYTCNATGACNGCNTCNGGNYTN------------ ---------------------------MGNTTYGGNCCNGAYGGNYTNACNTAYTAYTCN GCNCAYYTNGGNGAYMGNTGGGARGCNATHTTYYTNGAYCCNTAYGARATHTCNYTNATH GGNYTNTCN------CARGAYGAYTCNGGNTTYYTNGARGCNACNGARATGATGMGNCAR CAYAAYCCNAAYGTNGCNAARGAYTGGTTYACNGGNYTNCCNACNTCNAARCAYMGNTTY GTNCCNTAYAAYGGNGGNATHTCNYTNCARCARYTNTCNTGGYTNAARAAYGCNYTNCAR AGYGCNGARGCNCARGCNMGNAARGCNYTNATHTTYYTNCAYGTNCCNYTNTTYGARGCN GCNACNAARGCNAARACN------GTNGTNTGGAAYTCNGARGARGTNYTNCARGTNYTN CAYTCNCAYAGYACNGTNGTNGCNGTNTTYGCNGGNCAYGAYCAYAAYGGNGGNTAYGCN GTNGAYGCNGCNGGNATHCAYCAYATHACNATGAAYTCNCCNYTNACNGCNGARCCNGGN AGYGAYTGYTAYGCN--------------------------------------------- ------------------------------------------------GTNYTNAARAAR TGGGCNACNAARTTYGARGAYGARGGNATHCCNGAYGCNGTNTCNAGYGCNGARTAYATH ACNGCNCAYGTNGTNGGNAARAARACNYTNTAYGGNGTNAAYAARGAYGARTAYTTYYTN GAYGAYGCNGAYGTNGTNGCNATHAAYGAYTTYTGYAARYTNMGNATGMGNMGNATGCCN GTNCARTAYATHYTNGGNGARTGGGAYTTYGAYGGNYTNACNYTNAARATGATGCCNCCN GTNYTNATHCCNMGNCCNGARACNGARGARYTNGTNACNCAYTGYAARCAYATHYTNGAR TCNAGYCARTGYYTNATGGARCAYCAYMGNMGNCCNGTNATHGTNGARATHGGNTGYGGN ACNGGNGCNATHAGYYTNGCNYTNYTNAARCAYTTYAARGARYTNCARTCNGTNTGYYTN GAYATHYTNCCNGARGCNTGYACNYTNACNCARTCNAAYGCNGARACNGTNGGNGTNAAR GAYMGNATHCAYATHATHAAYGGNAAYTTYACNCAYTCNACNGTNATHTCNGARYTNCAR GCNYTNGGNCCNTAYTGYYTNYTNGTNAGYAAYCCNCCNTAYGTNACNTGYGAYCARATG AARGAYYTNTCNCCNGARATHAGYMGNTTYGARAGYAGYGTNGCNYTNGAYGGNGGNGTN GAYGGNYTNGAYYTNGTNMGNCAYATHYTNTAYCARGCNMGNGCNYTNGTNATGCCNAAY MGNCAYGTNTTYYTNGARGTNGGNGARAAYCAYCCNGAYGTNATHGARAAYTTYGTNATH AAR---AAYAARTCNYTNMGNYTNCARTAYATHMGNGGNATHMGNGAYATHAAYGARMGN AAYMGNTTYTGYCAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GGNCAYCAYACNATGACNTAYCCNAAYAARMGNACNACNAARYTN AAYCAYYTNGGNCARGTNTTYMGNGARGARGARACNATHYTNCCNYTNTAYAARGAYGAR ATHGAYGTNCARGGNGCNGAYGGNCAYATHTAYAARGGNMGNATGGARGCNGCNAARYTN GARGCNAARYTNCCNGTNAAYYTNACNGCNAARCAYTCN---TAYCCNGTNTAYATGGAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGTTYAARAAR CARAARCCNAARGTNYTNCARAAYGGNAGYMGNGARTCNGTNGAYAGYCARGTNAGY--- ACN------AGYAAYGARAAYYTNTCNCCNGGNACNAARGARACNAARGAYACNGTNGAY AARATHYTNCAYCARMGNGTNCAYTTYCARGTNTAYTAYYTNGGNYTNGTNCCNGAYATH AAYYTNACNAAYTCNAARAARMGNGAYACNGARGCNCARYTNATHGAYGTNGTNGARGAR AGYCARATHGARGGNAARYTNCARGTNACNGCNACNGAYGARAAYAARGTNGTNATGAAY ATHTCNMGNCAYGGNATHAARGTNYTNGAYATHGCNGGNAARGARGTNYTNCARMGNCAY CCNYTNCAYACNATHGCNCARYTNACNGARTAYAAYGAYGGNTTYAAYMGNCARAAYATH GCNGTNAARATHGGNCARGTNGGNAARAAYGTNTAYCARTGYTAYGTNTTYCARTGYCAY TCNGAR---------ATGCARGAYTTYATHATHGGNYTNTGYYTNGCNGTNAGYTCNTCN ATHTTYATHGGNTCNAGYTTYATHYTNAARAARYTNGGNYTNYTNMGNTAYGCNMGNAAR GTNAGYGTNMGNGCNGGNCARGGNGGNYTNGGNTAYYTNMGNGARTGGATGTGGTGGGCN GGNATGATHYTNATGACNGTNGGNGARTTYGCNAAYTTYGCNGCNTAYGCNTTYGCNCCN GCNACNYTNGTNACNCCNYTNGGNGCNYTNAGYGTNATHGTNAGYGCNGTNYTNTCNGCN MGNGTNYTNAARGARAARYTNAAYATHYTNGGNAARYTNGGNTGYGTNYTNTGYGTNYTN GGNTCNACNYTNATGGTNATHCAYTCNCCNAARGARCARGARGTNCAYGAYGTNGARGAY YTNATGYTNAARATGAARGARCCNGGNTTYATHYTNTAYGCNYTNTTYYTNYTNATHGTN TCNYTNATHATGATHTTYTAYTTYAGYCCNMGNTAYGGNCARAARAAYGTNYTNATHTAY ATHACNATHTGYGCNTCNYTNGGNGCNTTYACNGTNATGGGNTGYAARGGNGTNGGNACN GCNATHACNGCNACNGCNMGNGGNCAYAAYGARTTYAARAAYTGGYTNACNTAYGCNYTN ATHACNATHGTNATHGTNTGYATHYTNYTNCARYTNAAYTAYYTNAAYAARGCNYTNGAY ACNTAYAAYACNGCNGTNGTNACNCCNATHTAYTAYGTNTTYTTYACNTCNTGYGTNATH GTNGGNTCNGCNATHYTNTTYAARGARTTYTTYAARATGGAYGTNYTNAAYATHGTNGGN GAYYTNTGYGGNTTYTTYGTNATHGTNATHGGNATHTTYYTNYTNAAYGCNTTYAARGAY YTNAARATHTCNYTNMGNAAYYTNCCNAARGCNTCNAARGARGCNGAYGAYYTNACNAGY AAYAAYATHAAYGGNAAYAAYTGYMGNGAYATHGARGCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATHGARGARGAYMGNATGGARMGNMGNGARAARCARATHGCNTAYGGNAARATGACN GARTCNTAYCARYTNTAYGCNAARACNGTNCCNAARAGYGARMGNGGNGAYAAYMGNAAR MGNCAYCCNMGNACNCCNATHAARYTNTTYMGNTGYAGYMGNMGNAAYTGGGAYGCNCAR ATHAARGCNTGGAARAARTAYGTNCAYCARTGGGCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNGARTCNGTNTGYCAYGARYTNGAYATGTCN GARATHATHATHCCNCCNCCNATHAARACNGARGAYGTNCCNYTNCCNCCNGGNAGYCCN AARACNYTNTCNGGNTCNGAYCARGTNAARCARGARAAYCARGTNGARGAYYTNACNAGY ATHYTNYTNCCNGAYAAYCCNCCNCCNGAYGAYAARAGYTCNYTNAARGAYATGATGGAR YTNGGNAARAGYAGYGTNTCNTTYTCNTTYAAYAARACNACNAGYAARATHGCNACNACN TCNGCNTTYAAYCARGARGARCCNGAYCCNATHGARATHCCNCCNACNMGNCCNYTNACN YTNATGGAYAGYATHGARGARGARAARMGNYTNATG------------------------ ---------------------------------GARCARGARTCNCARCARTCNGCNGAR CCNAGYGAYAARAARYTNGAYGCNCCNGCNAARCCNMGNYTNYTNGARGAYTTYGTNCAR GTNACNYTNATGAARGARGGNGCNGGNGAYATHCCNTGGCCNGTNGARACNATHAARTAY ACNAGYACNCARCCNAGYATHCAYTTYGCNTGYAAYCCNATGCARTTYGAYTTYAARGAY GTNYTNAARGCNGGNGGN------------------------GGNGGNGGNGGNGCNGGN GAYAAYGTNAARAARTCNGARGARCCNAARGCNGARAARGARAAYAARGARGGNAARGAR AARAARAARCAYTCNTCNMGNAARAARAARAARMGNAARAARAGYGGNAGYMGNAARGCN GAYGGNGTNACNGTNGARCAYGAYGGNAARGARAAR---ACNGARGGNGGNGARAARGAR GGNGCNACNTCNGARGGNGGNAARAARGGNAARAARAARAARMGNAARAARMGNAARAAR GGNAARCAYMGNCAYAARAGYAARAARGARGGNGAYGGNGCNGAYGCNAARGAYGGNGCN GGNGARGGNGGNGTNGARGAYAARTCNAARMGNMGNTCNCAYMGNAARMGNACNCAYAAR GARMGNGAYGGNGGNGCN---GARAARGCNGGNGTNGGNGAYGCNAARGARCCNGARAAY GARGGNYTNGTNAAYGGNAARAARAARGCNGARTCNTCNTCNGCNGCNACNAARCAY--- ---AARCAYAARMGNAARCAYMGNMGNMGNMGNCAYGAYMGNTCNGARAARGCNAARGCN ATGAGY------------GCNTCNGARAARAARTCNGTNGAYACNGTNAAYGCNAARGAR CCNAARGTNAARATHGAYTAYGAYGAYGARGARGARATGCAYATHCCNACNGAYACNGAR CARGAY---AAYGCNGARCCNAARATHAARMGNCCNTGYMGNTCNMGNAARMGNCAYMGN MGNAAYAGYAGYCAYAARGCNGGNGARATHGARACNTTYAARACNGARGAYCARAGYGGN GCNGAYCARYTNAAYATHACNTTYAARACNCAYAARAARATGCARGARAAYGCNGCNAAY AARYTNCCNGAYATHGTNAARAGYGTNGGNGGNGGNATGAGYAARACNATHATHTCNTCN AARGARAGYGAYTCNCARCAYTCNAARACNCCNAAYGGNGAYATHAGYGGNCCNMGNAAR MGNGGNACNAGYATHTCNAGYACNGARGGNACNACNCCNGCNAARGTNACNAARATGGAY AAYGCNGTNACNGTNGARGAYACNTGGAGYAARATGGARGGNYTNTAYGARGAYAARGGN GARGARGGNTCNAARAGYAARTGGGAYACNAGYGAYAGYGARGGNGARGAYGCNYTNCAR AARACNYTNGAYGCNAAYGCN------------AAYGARGARAAYAARGCNGAYCARCAY ---CARCAYAARCCNACNAAYGGNAARATHCCNYTNACNAARTCNYTNYTNYTNACNAAY GGNATG------------------AAYCAYGTNAARYTNCAYGCNYTNCCN--------- ------GCNAAYAAYAAYAAYCCNACNTCNAARMGNGAYGGNACNGARAARGCNGGNGAY GAYGAYGGNAARTCNAGYTCNACNCAY---AARCARTCNTCNTCNCARMGNGARGGNMGN TCNMGNAARMGNAGYAGYMGNMGNTCNTAYACNTCNTCNGARTAYTCNTCNCAYTCNMGN TCNTAYTCNMGNTCNMGNTCNGGNTCNTAYMGNAGYTAYTCNGAYGAYTCNMGNTAYAGY GAYTCNAGYMGNTCNCAYAGYMGNTCNTCNMGNAGYTAYAGYMGNAGYMGNTCNMGNCAY MGNTAYMGNMGNMGNTCNTCNTCNAGYMGNGGNMGNAGYMGNAGYTAYAGYTAYAGYAGY MGNAGYAGYTCNAGYMGNTTYMGNTCNMGNTCNTAYTCNMGNTCNMGNAGYTAYACNMGN TCNMGNTCNMGNGGNMGNGGNTAYCAY---AGYAAYTCNMGNAGYCCNTCNMGNMGNAGY AGYGCNAARYTNAARMGNATHYTNAARTCNCCNYTNGCNATHGTNCCNGTNACNACNTTY ACNGTNGCNCCNGTNACNGGNTGYACNAGYGGNGGNGCNAARGAYAGYGCNTCNAGYGGN AGYGGNGGNGGNGGNGGNGGNGGNAAYGGNGCNACNCCNGAYGAYATHCCNYTNCCNGCN AARGAYGCNGCNTCNTCNTCNGCNACNACNAGYAAYTCNAGYCCNAARAARGAYAARGCN GTNYTNATHGAYATHCCNYTNCCNACNGCNGGNAARCCNGCNCCNACNGAYGGNAARGAR AAYTCNAAYTCNGGNGAYGGNGCNGCNGTNACNAAYAAYCAYGGNGAYCAYACNTCNGTN GCNGCNGTNCCNTCNGAYCCNCAYGTNCAYCARCAYAAYGGNAGYGGNGGNAAYCCNAAY CCNAAYCCNCAYGTNAAYCCNACNGGNGAYGGNATHATHGGN---------GGNGARAGY AAYYTNCARTCNGAYGAYTTYGGNGCNGGNGGNAGYATGGTNAAYCCNGAYATGYTNGGN GGNTAYGAYCARGAYTCNTAYAAYCARATGGGNTAYGGNAAYCAYGAYGCNGCNTTYTGY GARGAYACNGGNTAYGAYAAYTTYGARTTYGAYGGNAAYGGNGAYTAYGAYCARCARGGN GGNGGNTAYGAYGAY---CAYCAYGAYTAYGAYTAYAAYCCNGAYCCNTAYCAYCAYCCN CCNYTNMGNCAYCARGGNCCNCCNCAYGGNCAYCAYATGMGNGGNCCNCCNCCNCCNGGN TAYMGNGGNCCNCAYCCNMGNATGTTYCCNCCNGAYATGMGNTTYGGNCCNCCNMGNCCN GGNATGGGNCCNCCNMGNATGMGNCCNCCNAAYGGNCCNATGGGNCCNCAYCAYCCNATG GGNCCNMGNGGNCCNMGNCCNCCNATGGGNCCNGGNGGNCCNATGGGNCCNCCNGGNATG MGNGGNCCNCCNCCNMGNGGNCCNCCNCCNMGNGGNCCNCCNGGNATGMGNGGNCCNCCN GGNATGCCNGGNCCNMGNGGNCCNCCNCCNMGNTCNGGNATGATGGGNCCNCCNCARGGN GGNCCNATGGGNCCNAAYGGNCCNMGNCCNMGNATGGGN---CCNCCNYTNMGNATGGGN CCNCCNCCNCCNGGNCARGGNCARGGNCCNATGCCNCCNCCNCCNGGNGGNCCNMGNAGY MGNATGCCNCCNCCNGGNCAYATGCARGGNCCNCCNATGMGNGGNGARAGYCAYCCN--- ---------------CCNCCNCARCARMGNCCNGGNATGCCNCCNCARATHMGNGGNCCN ATGCCNCCNAAYATGGCNCAYCCNCCNCCNAAYTTYAAYATGCCNCCNCCNTCNTCNGAY AGYGGNCCNATH---------------------AARCCNCCNGAYTCNATGGARCCNCCN CCNYTNCCNCCNCCNAARGCNCCNACNCCNCARCCNCCNCCNCCNCCNAARAARGARGAR GARAARAARGARGARATHAARCCNATGGTNCCNGAYATHCCNCCNGARCARGCNGARCAR TAYMGNAARYTNMGNGARAARGCNCARAARCAYGCNAARAARCARYTNMGNAARGCNGAR CAYCARGCNAARGGNGARCCNGARAGYAGYGAYGAYGAYGAYGAYGARGARACNGCNAAR AARAARGARGAYGCNGCNAARYTNGCNGCNGARCARAARGARATGGARGARGCNGCNYTN YTNGCNGCNCARGGNGGNGARAARGTNGCNGTNGARGARGGNGGNGCNATHYTNGTNCCN TCNCCNACNACNCCNYTNGCNGTNCARCARCARGCNGTNTAYATHCARCARCARCCNATG GGNGCNGCNGCNGCNGTNGCNCAYTCNCCNTAYGGNYTNGTNTCNTCNCAYCAYYTNGTN CAYGCNGCNCAYCCNGCNYTNCARGCNGGNCAYCCNCAY---GCNGCNCAYCAYCAYGCN YTNGCNGCNGTNGGNCARCCNCARYTNGTNCARYTNCCNAAYGGNCARGTNGCNTAYGCN ACNCCNGCNAARCCNCARTCNGTNCCNYTNCARGCNGGNGCNCCNGTNATHGCNATG--- TCNCARGCNYTNGCNGCNTCNTCNCARTCNGCNGTNCCNCAYCARYTNGTNYTNCARTCN GGNGGNATHCCNGGNCARGTNCARYTNGCNCAYGCNGTNCCNGGNGCNCARTAYGTNTCN CAYTTYATGGCNGCNCARGCNCARGCNCARGCNCARGCNCARGCNCARGCNCAYGCNCAR GCNCARGCNGCNCAYATHCARGCNGCNCAYGTNGCNCARGCNCARGCNCAR---GCNCAR GCNCARGCNCARGCNCARGCNCARGCNCARGCNGCNCARYTNCAYGGNYTNGTNCCNGGN GTNCAYCCNYTNGCNCARCAYATGATHCCNGGN------------CARCCNCARGGNCAR ATHATHYTNGTNCCNMGNATHGCNMGNCCNCAYATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AGYAAYGTNTTYCARTGYYTNATHGARATGGTNCAYGTNCCNGARGGNATHAGY AAYTAYGARGARGCNYTNCARGAYGCNGARGARGARAAYATHMGNACNTTYTAYGTNMGN AAYYTNAARYTNAAYATHACNAGYGAYGAYATHCARTCNAARCARGAYYTNYTNAARAAR GCNATGTCNCAYATHYTNAAYATGMGNGAYATGGARGARATHTGYCARGCNTTYGGNYTN AAYAARAARGAYATHGGNAAYTTYAGYMGNAARTTYGARTCNGAYGAYGCNYTNAARACN GGNYTNYTNGARGARTGYTCNAARATGGGNATHMGNGAYYTNTGGAAYATHYTNGARCAR GTNAARCARGARACNAGYYTNGCNGAYTTYMGNGGNAARAARYTNGCNGTNGAYTTYAGY AGYTGGTTYGTNAARTGYGARGCNACN------CCNTAYACNAAYMGNTCNATHTTYTAY MGNATHGTNGAYYTNATGTCNAAYGGNATHACNCCNGTNTTYGTNTTYGAYGGNCCNAAR TCNCCNGARTTYAARGCNMGNAARMGNGGNGARTCNTAYTTYMGNGCNACNTCNCARTGG AARGARYTNYTNAAYGARATGGGNTTYCCNACNYTNTAYGCNGAYGGNGARGCNGARAAR GCNTGYGCNCARYTNAAYTCNTCNAARGCNGTNGTNGGNTGYGTNACNGAYGAYGGNGAY GTNTTYGCNTAYGGNGCNACNACNGTNYTNAARGAY---TAYMGNACNGGNAGYAARGAR ------ATHCAYYTNTAYGARYTNTCNGCNATHGARGARAARATHGGNATHGGNCARAAR GARATGATHGCNGCNGCNATHYTNATHGGNTGYGAYTAYCAYAARGGNGTNGARAGYGTN GGNMGNGARGARTTYAARGAYYTNYTNAARGARYTNMGNAAYAAYGARGTNCCNGAYATH ATHGAYMGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARAAYCAYTTYCARATGGCN AARAGYAAYYTNGARMGNCARMGNACNAGYMGNYTNAARCARYTNCAYGAYCAYGCNAAY MGNYTNMGNCAYGARGTNAARYTNYTNGAYYTNGAYMGNCARMGNCAYACNGTNGARGTN MGNAARMGNYTNGARCCNGARAARGAYTAYAGYTAYGAYGARGTNCARATHCAYAAYACN GARAARMGNYTNGGNGCNAAYATHGCNTCNTTYTAYYTNGAYAARAARYTNAARTAYCCN ATGMGNYTNMGNTCNATGAARGAYATHMGNGTNACNCCNACNATHTCNAARGCNMGNGCN AARATHMGNACNAGYGAYGTNAAYAARACNYTNGARGARGARAARAGYTTYTCNMGNCAR GARMGNGCNCARACNGCNAARACNACNGTNTCNTCNATHGGNAAYACNAGYTTYAAYAGY MGNMGNMGNGGNTCNMGNTCNGCNCCNYTNCAYAAYACNMGNTCNAARACNYTNTTYCCN GCNATHGGNGGNGARAAYAAYAARGARGGNAGYGTNTCNGGNAGYGARAARGAYCAYCAY ATHCARCARGTNAARTTYGCNTTYGARAAYCCNYTNAARATHYTNGCNTCNAGYGARGAR AGYGCNAAYATGTTYGCNMGNTCNTGYTCNTAYTAYCCNGGNTCNACNMGNGCNATGGAR GTNMGNAARATHTCNMGNYTNMGNGARGARCARCARAARGCNYTNTCNGAYACNGARGAR CARYTNAARCARATHGARAARTAYAARTCNGAYTAYAARGCNYTNCARAARMGNYTNAAR ACNYTNCCNGAYAARGTNACNCAYGAYGTNATGGTNCCNTTYGGNAARYTNGCNTTYATG CCNGGNAARYTNGTNCAYACNAAYGARATGYTNGTNYTNYTNGGNGAYAAYTGGTTYGTN GARMGNTCNGCNACNCARGCNTGGGAYATHGCNGGNMGNMGNATHAARGARYTNGAYAAR MGNATHGCNGARYTNAARGARCARAARAGYYTNYTNGARCCNMGNYTNGGNATGACNTCN GARYTNCARAAYGTNGCNGARGGNATHGGNGAYTAYCARGARATHGTNGARGARTAYGAY GARGARAARGARMGNYTNTGGGAYGARCARCAYAARAARAAYGTNMGNCAYCAYCAYGAR ATGYTNMGNYTNAAYGARAARGGNGAYGCNGGNMGNGGNGCNGAYTTYAARGCNCCNTCN GARAARAARAGYGAYGARGAYYTNTGGTCNMGNYTNGARTTYYTNGARAARCARGARGCN GARMGNGGNGARYTNGARTCNGAYGGNTCNGAYAGYCARGGNGGNGGNGAYGAYACNCAR MGNAARAARGARGTNTCNCCNACNCARGAYAARAARGTNAARTGGATHGAYAARAAYTAY GGNGAYAAR---GAYAGYGAYGAYGGNGAYGGNGARTAYGAYGAYGAYGAYGAYGGNGAY GTNTAYGAYYTNGAYGAYGAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CARGARGAYGAYAARAAYTCNAGYAGYGAYGARGGNCCNYTNGTNCAR GARGARCCNYTNAARMGNTCNGCNTTYGCNTCNTTYYTNATGGTNYTNGTNAARCARAGY TAYGTNYTNTCNYTNATHGGNATGATGGCNTGGAGYATHACNTAYCAYTCNTGGYTNACN TTYGTNYTNYTNYTNGCNGCNTGYTTYYTNTGGATGATGCCNAAYTCNMGNAARTGGTTY YTNMGNTCNTCNCCNTTYATHYTNTTYTAYGCNGARGGNYTN------------------ ---------------------------------------------AAYACNATGGTNTTY TAYGTNTAYYTNACNAARTTYAAYCCNAGYTCNACNMGNTCNGCNATHYTNGCNYTNGCN TTYTTYGAYYTNGTNGCNAGYTGYATHTCNATGCCNGGNGARATGATHGAYYTNMGNTAY TCNTAYAAYTTYAARAGYGAYATHGTNTGYAARTGYTTYMGNYTNGGNACNACNGTNGTN YTNATHGCNTCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYGTNGTNATHGGNTAYCAYGAYGAYGAYYTNGAR TTYGTNAARAARYTNGTNAAYAARYTNMGNTCNGCNGGNYTNAGYGTNTGGTAYAGYCAR CCNGGNGAYGAYGGNAARAARACNAGYGARGCNATHYTNGGNTGYAARGTNTAYYTNCCN GTNYTNACNGAYATGTCNGCNGTNGAYAARAGYATHCARGARCARYTNTCNYTNGCNTAY ATHTCNAAYTCNGCNATHTAYCCNYTNGGNAARATHCCNTTYCAYYTNYTNGCNCCNAAR YTNAAYGGNGGNGCNMGNYTNATGYTNGCNAARATHAAYTGGTCNTTYATHYTNAARGAR GARCAYTTYGARCCNMGNACNGAYYTNATHATHGAYTGYATHAARAARGAYATHCARAAY ATHGARAARATHTTYGAYCCNACNGCNGAYGAYTCNGGNTAYGTNTTYACNCAYGGN--- ---ATHMGNGTNCCNATHTCNCAYYTNTCNAGYACNGCNGARCARGARCCNGAYTTYGTN GCNTTYAGYCARGGNATHGAYYTNAGYTCNATHAGYCARGAYACNCCNTTYTGGGAYMGN CAYTTYAARGGNAARAAYGARGTNACNTGGATHGARTAYMGNGAYAARTTYYTNCARGAY TAYGCNGCNAARATHGTNGARGGNTTYTCNGAYAAYCCNGARGARMGNAARAARYTNTTY GTNAAYYTNATGTAYAARGAYGTNTTYTCNYTNAAYAARATHGTNAARMGNTCNGTNTAY GAYAARTTYTGYGGNAARCCNCAYCCNCAYGCNTTYTTYACNGGNATGCARGAYTAYGTN ACNGCNTAYGCNTCNYTNMGNGARGTNYTNAGYATGGAYAGYAGYYTNMGNATHTCNACN ATHCARAAYYTNGGNMGNTTYMGNTTYCCNGCNATHGTNTCNGGNYTNTCNGAYATGYTN GAYGAYGARGAYCCNAAYGTNMGNGCNGTNGCNGCNATHGCNYTNGCNCAYGCNGGNAAR AARACNCCNTCNACNGCNGAYAARATHATHGCNYTNYTNGARGAYGARGAYMGNYTNGTN MGNGARAGYGCNTGYYTNAGYYTNGGNTAYYTNMGNTCNACNMGNGCNGTNACNCAYGTN GTNGAYMGNTGGMGNAAYGAYCCNATHTCNACNGTNMGNGARGCNGCNGARYTNGCNYTN AGYMGNATGGAYGCNCCNGAYGCNGTNCARTGYATGAARGTNACNAARGTNYTNTCNTCN GARATGAAYGCNYTNAARCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR AARTCNAAYCARTGGTTYGGNGCNACNATHAARAGYTCNGGNGARAGYGGNGTNATHGTN GCNTGYGCNCCNMGNTAYYTNTAYTTYGGNTTYGAYYTNAARAARMGNGARCCNGTNGGN ATGNNNTGGGTNGCNAARACNTCNACNACNGARTAYGARAGYTAYTCNCCNTGYATHGAR GAYATHGARAARATGATHGARMGNTGYGARAARMGNATHGAYGARYTNGARMGNAARGAY MGNYTNACNGAYATGTCNGAYGARCARTGGCARGARYTNAARAGYGARAARAARCARYTN GARAARCARGTNAARAARTAYMGNAGYGARYTNMGNGGNYTNMGNTGGCARAAYTGGAAR AGYATGATHACNTCNGTNTGYATHTTYGGNYTNATGTAYTTYGTNTAYYTNATHTTYTTY GAYTCNGAYTCN------------------AARATGGAYACNTGYGTNCCNAGYCCNAAY GTNATHAAYGCNCCNTTYYTNCCNAGYCCNCAYTCNTCN---ATHTAYGARCARGAYMGN CCNAAYATGTAY---------TAYGGNAGYTCNAARGTNGAYTAYAAYYTNGAYGTNTGY GGNGCNGTNYTNGARGAYAGYAGYYTNYTNGAYGAYAAYTAYGARGAYGCNACNYTNGGN AAYATHYTNACNCCNGARATHYTNAAYTCNATGGCNAGYTCNTCNTCNGGNTTYCCNCCN ACNAAYYTNTGGAAYTCNAAR---------ATGACNATGAAYGARTCNTCNTCNYTNGAY CARGGNGCNGARCCNCCNTTYATHCARYTNGGNATGGAYTCNGARATHTTYATH---CCN GARYTNYTNAAYYTNGAYTCNAAYGAYAGYAARTTYTCNTTYCCNGAYTTYGAYTGY--- ---ATGACNAGYAAYCCNCCNTCNTCNTGYCARACNCCNACN------CCNTCNGARCCN AARTCNGARTTYGTNTCNGCNGAYMGNGTNAAYTTYGTNTCNMGNAAYAARGARAAYATG TCNTCNTCN---------------GCNACNAAYYTNGAYATHATGGGNCARGAYTTYGTN CARAARAARTTYCCNACNAARTCNAAYTTYCCNCCNMGNAARTCNGARCCNCCNGTNGGN ATHGTNGCNCCNGTNAARATHCCNGARGTNAGYAARACNTTYGAY--------------- ---------------------------------CAYCAYCCNGTNAARATGGARGARGAR GARYTNAARTCNAGYTTYAAYACNTCNTGYGCNGCNGAYTTYGCNGARGCNTCN------ ---------------CCNCARACNGTNCCNTCNTTYAAYGTNTCNAAYGTNGARACNGGN TAYAAYAAYCCNATHAARTCNGARCCNATHTCNCCNGAR---AAYACNAGYGGNTGYYTN AARMGNTCNTCNACNGAYGAYAARTGGGARGTNGTNAARCARTAYATG---YTNCCNGAR GARCCNGTNAARAGYAARMGNMGNMGNTGYGAYTCNGGNAGYTCNGGNATHACNTCNGAR GAY---GGNGAYGARGAYGAYAAYGAYTAYGCNTTYCAYAAYGAYTAYGARAGYGAYGAY GAYAAYTCNGAYYTNGAYGCNGAYYTNGCNCAYATGAARCCNGGNAGYTGYGARTCNYTN ATHGGNGCNGGNAARAARCARAARCARTAYTTYTGGCARTAYAAYGTNCARGCNAARGGN CCNAARGGNACNMGNYTNAARYTNGCNGTNGARACNCCNGCNGAYCCNCAYGTNYTNAAY GGNTTYGARGAYCCNGTNTTYGAYGARGGNAAYACNACNGTNGCNGGNATHMGNCAYGGN GGNAARGCNMGNAARGGNGAYGGNAAYGARGTNACNCCNAAYCCNCAYAARYTNTTYAAR ATHGGNCAYCARYTNYTNMGNYTNAAYAARAARATHAAYGCNTGYCARYTNGGNTCNGAY GTNCCNYTNGCNCARMGNAAYGARTCNMGNAARGARAARAAYAARYTNGCNTCNMGNGCN TGYMGNYTNAARAARAARGCNCARCAYGARGCNAAYAARATHAARYTNCAYGGNYTNGAR ATGGARCAYGGNCARATHAAYAAYGTNYTNMGNYTNYTNTGGCCNGARYTNMGNGARMGN GCNAARMGNATHCARAAY---------GARCAYCARATHGAYGARAARCCNGAYCCNGAR AAYAAYYTNTTYAAYAARYTNACNGGNTAYATHAGYTCNAAYYTNAARACNATGGTNGCN GGNAAYACNACNGAYTAYGTNAAYAAYGTNATHATGACNGTNGARAARGGNGAYYTNTCN GGNGGNYTNAARGTNMGNMGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TGGAAYGAYATHGCNGCNAGYGARGTNGGNYTNCAYGARGARGTNYTNGGN CARATHMGNTCNACNGTNGGNAARGCNYTNYTNYTNATHGARCARMGNTTYAARCARTTY TCNGGNYTNGTNGAYAAYTAYGTNTAYAAYYTNGGNGARAARGARACNACNCCNACNGAY YTNCARGGNTTYTGGGAYATGATHTAYTTYCARGTNGARGAYGTNAAYAAYCARTTYAAR GARYTNAARGARYTNCARCARTCNGGNTGGCARGTNAARCCNAARACNCCNAARGCNTCN ACNYTNAAYYTNAARAARAARATHACNAARGGNAARCCNATHGTNAARGGNGTN------ ------AARTCNAAYTTYGCNGCNTTYMGNGCNGARYTNCARAARAARAARGCNGCNAAR GCNTCNYTNAARGAY---GARGAYYTNAARAARATGAARGTNCCNGARYTNAARCARGCN YTNAARGAYAARGGNYTNTCNACNTCNGGNACNAARCCNGAYYTNATHAARMGNYTNGTN GARTCNATGGGNGCNTCNGGNGAYGGNAGY---GAYCCNGTNATHGAYGAY--------- ------GAYGARATHYTNAARGAYGAYTCNACNCCN------------------------ ---------------------GTNGCNGCNGCNGTNATHCCNAARACNGCNACNGTNGAR TCNGTNGARAARAARGCNTCNAAYGGNATHGCNCCNACNAAYTCNATHCCNAARCCNAAY GTNCARATGGCNGCNGAYACNACNGTNACNGCNAARCCNACNGARGTNAARAARYTNACN GAYGCNGARMGNYTNAARYTNMGNGCNGARAARTTYGGNGTNGCNTCNGARCARGCNAAR AARGAYYTNMGNGCNCARMGNTTYGGNATGGCNTCNAGYGARAAYAARTCNGGNAARATH AGYTCNTCNGTNGGNCCNGTNGAYGTNGARAARYTNAARAARMGNGCNGARMGNTTYGGN GTN------------TCNACNAGYTCNGTNACNGARGARGARAARAARMGNAARMGNGCN GARMGNTTYGGNTCNAGYACNTCNACNTCNTCN---------ACNTCNACNGTNAGYYTN AAYTCNAGYGARGTNGARGCNAARAARMGNAARMGNGCNGARMGNTTYGGNYTNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNTTYAGYTGYGARGTNTCN CCNGGNTTYTTYATHACNCCNGCNTTYTCNGAYYTNTTYCCNYTNYTNCCNTCNGAYYTN CARCARATHAAYTAYCARCAY---GGNGTNAARTAYACNAARGAYGCNAARAAYTGYGAY AGYYTNAAYGAYGTNGAYATHACNAAYYTNCCNGARGAYYTNGARATHCARATHMGNYTN TTYTCNACNTCNYTNGAYGGNYTNYTNCARTCNATGAAYGTNAARGARGAYATHTAYTCN ATHGGNTGYYTNAGYMGNATHATHGCNACNGAYYTNGAYAGYTTYCCNCCNGCNAARGCN MGNMGNAARACNGCNCARTCNMGNATGTCNYTNYTNYTNGTNGAYMGNAGYYTNGAYYTN GCNTCNGTNGTNACNMGNCARTCNGAYGTNYTNYTNGAYAARATHTTYAAYACNYTNCCN TCNYTNAAYGAYAAYGAYACNGAYMGNYTNATHGAYATGMGNGAYYTNTGYCAYTGYTAY AAYACNAARTCNAGYMGNAGYGTNATHYTNCCNGGNTGYYTNGCNCCNYTNAAYGTNAAR GAYTCNCCNAGYCAYYTNACNGCNACNATHATGAARAARCAYAARGARGCNYTNATGGAY ATHAAYMGNMGNYTNGTNGARACNGTNACNTCNGARAARYTNCCNYTNGAYATGTCNMGN MGNCCNAGYMGNGTNACNGCNGAYYTNYTNGAYACNACNYTNGCNYTNTTYAARGGNAAR TAYGCNYTNATHCARAARCAYYTNAAYACNYTNCARGTNTCNATGGCNACNAGYCARACN YTNAARCAYTCNTCNACNYTNCAYCAYGAYAGYGTNATHGCNAARGARAARAAYATGYTN CARGCNATHGCNGAYACNGARGGNGGNGGNGGNGARGAR---------------GARGAR AGYGCNTAYCCNTCNGCNTTYTCNYTNATGTCNAARYTNYTNGTNACNGARYTNGARAAR GARMGNGARAARMGNGARTTYACNYTNGAYGAYGTNYTNCAYYTNYTNGTNTAYATHTAY TCNGTNACNGAYGGNAGYAGYGARAAYCCNGARGARGTNAARYTNYTNCARGAYCAYYTN GTNGARGCNATHGTNAARGAYAARGAYTGYYTNCCNCCNATHATGAARGCNATHGTNGGN GAYAARGTNACNGARTCNATHYTNACNGAYCARATHGARAAYATGTGGGARAARYTNGAY AGYYTNYTNGARYTNMGNMGNGARYTNAARGARTTYGGNAAYYTNYTNGAYCCNGGNGGN GCNATGAGYCCNGCNTCNGTNAARCCNYTNYTNAARCARATHATGGARAARATHGTNGAY CCNGGNAARCCNGARYTNCCNGAYATHGARTGYAARTCNGGNGGNYTNAARGAYYTNYTN AARTCNGGNTTYGGNTTYTTYAARAGYTCNGCNAARCCNMGNCCNGGNGAYGCNCCNYTN YTNATGGTNATGGTNATHGGNGGNGTNACNGGNTCNGARGTNMGNATGATHAARGAYATH GTNAGYAGYGCNAARCCNGGNTTYGARGTNATHGTNGGNGGNACNMGNATHAAYGAYACN GARTCNACNYTNAARTCNTTYYTNGTNAAYGAYAAYATHAAYATHAAYATGYTNAARGCN GCNYTNAARACNAGYGAYTGGATHAARYTNGAYACNTGGGARTGYGARCARAGYGCNTGG ATHGARACNATHAARGTNYTNMGNCAYGTNAARCARYTNGTNGAYAGYCARTAYYTNTCN AAYGTNAARCCNTCNCCNAARMGNMGNAARAARCARCAR---GTNTCNGAYYTNTCNCAY AAYAARGTNCCNAARATHGARGTNGARGARGAYCARYTNCCNYTNATHMGNTTYYTNTGY GGNGCNGAYYTNYTNGARTCNTTYGCNGTNCCNGGNYTNTGGAARGARGARGAYATHGAR AAYATHGTNAARAAYCAYGGNYTNGTNGTNATHAAYMGNGARGGNTCNAAYGCNGAYMGN TTYATHTAYGARTCNGAYGTNYTNACNAARTAYMGNGARAAYATHATHYTNGTNAAYGAR TGGYTNAGYYTNGAYATHAGYTCNACNAARATHMGNMGNGCNTGYMGNMGNGGNGARAGY YTNAARTAYGTNGTNCARGAYGCNGTNATHGAYTAYATHAARGARCAYMGNYTNTAYGGN YTNCCNGAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TGGAARTGGATHTTYACNGCNATGGARTGYMGNAAYYTN ATGGARCARMGNATGTAYACNYTNGCNATGCARAARYTNCARGCNGTNYTNAARCARTGY GTNGAYTCNATHAAYAARTGYMGNYTNYTNTGYYTNTTYGCNCAYTGYTAYTTYCAYATG GAYTGYCCNCARYTNTCNATHCARACNTAYMGNGAYGCNYTNCARGCNGAYTCNMGNTGY TAYTCNATHYTNTAYCAYYTNTCNYTNGTNTAYCARAGYYTNGAYYTNCCNGARYTNGAR YTNGARTCNYTNAAYYTNTGYGTNATGGCNYTNGCNGAYGARGARAARAARACNNNNAAR GAYAARATHCCNGTNYTNGGNGTNGAYGARYTNATHTGGTCNATHATHCCNCCNATHACN CCNGTNTCNTTYATHYTNGCNAARGTNACNTTYGCNAARMGNTGYYTNCARYTNAARMGN TAYCCNGARGCNGCNGARCARTAYTCNAGYYTNATHAGYYTNYTNCARGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNTGYGTNGAYAARCAY TGGAARGCNGGNGTNCAYCCNCAYCCNACNGARTGYCAYAARTTYGTNGARTGYTCNAAY GGNATHGCNTAYGARAARACNTGYCCNGCNAAYYTNGCNTTYAAYGCNCARGCNAARGTN TGYGAYGGNGCNACNACNGGNCCNATHTCNGTNTAYTCNCCNACNACNAARAARATHGTN ATHGAYCAYYTNTGYGTNGAYAARCAYTGGAARGCNGGNGTNCAYCCNCAYCCNACNGAR TGYCAYAARTTYGTNGARTGYTCNAAYGGNATHGCNTAYGARATGAAYTGYCCNGCNGAY YTNGCNTTYAAYCCNGARGCNCAYGTNTGYGAYGCNGTNAARYTNAAYTGYTTYACNTAY GTNACNCAYCCNCCNACNMGNACNTCNATH------ACNGAYYTNAGYCAYTAYTGYCAR GAYAARAAYYTNGARAGYGGNATHCAYGCNCAYCCNYTNAGYTGYCAYAARTTYATHGAR TGYTCNYTNTCNAARACNTAYATHATGGAYTGYCCNYTNGGNYTNGTNTAYGAYTCNMGN GTNAARACNTGYGAR------------------------------TGYGGNGGNAAYATH YTNATHGTNGGNGAYGGNGAYTTYTCNTTYACNGTNTCNYTNGTNAARCAYTCNGAYGTN GTNCCNGGNCARGTNTTYACNTCNAAYYTNGARACNGARACNTCNATHYTNCAYCAYGCN CARGCNTCNGAYAAYATGMGNAGYYTNAARGCNYTNGGNGTNTCNGTNTTYYTNGARACN GAYGCNACNGAYYTNCAYAAYCAYCCNYTNATHAGYAARGARAGYTTYGARMGNGTNATH TTYAAYTTYCCNYTNGCNGAYMGNCAYAAYATHAARAARAAYMGNTCNYTNYTNGCNGAY TTYTTYTCNAGYTGYMGNTCNATHYTNGCNCCNGGNGGNTGYGTNYTNGTNACNYTNTGY AARGGNCARGGNGGNACNCCNGCNGAYCARCCNATHMGNTCNTGGCAYGAYAGYTGGCAR GTNGTNGCNATGGCNACNAAYGCNAGYTTYYTNYTNMGNGARGTNYTNCCNTTYGAYCCN GCNGAYTTYCCNGARTAYCAYAGYGTNGGNTTYMGNTTYCARGAYAARAGYTTYAAYGTN ACNGGNGCNYTNACNCAYGTNTTYGARGARGGNACNYTNGTNGARGAYGGNGAYGTNAAR ATHMGNGGNGTNGTNYTNMGNGAYGGNATHTCNTAYTCNTGYAGYAGYTAYGTNGCNTCN CAYYTNAARMGNAAYYTNYTNGARGARCCNMGNAAYCCNYTNTGYATHYTNAARMGNAAY YTNGARGARMGNTTYAARAAYCCNATHATHCCNTCNCAYAARTCNATGGCNTAYATHGAY GAYTCNACNTGYCCNCCNGARATGATGTCNGARAARGCNMGNAARAAYYTNACNCARYTN GCNCAYGGNGTNATGTCNGGNGTNAGYGARATGAARGCNGARGGNTCNATHTGYTCNGGN AAYGAYGGNCCNGAYAAYAARGAYAAYGTNTAYATHYTNGTNAARAARGAYTCNGTNGAR ACNACNAARCCNGGNMGNAGYGARGARATGTGYAGYGARAARGCNGARAGYAAYTCNGCN CCNAAYCCNTAYGAYTCNCCNMGNGAYTGYAGYGAYYTNGARAAYAARAAYGARGAYAAY TCNGGNATHATGAARGGNAGYAAYTCNAAYGARTCNGGNTCNATGYTNAARGCNGTNGAY GTNYTNGGNMGNCAYGTNTCNGGNTTYCARAAYTCNTTYCCNTGYATHYTNTCNGGNCAR TGYATGMGNCCNTGYCAYACNYTNCAYAAYTCNAGYCCNATGAARCAYGARATGYTNATH YTNCAYAARATHGAYAAYACNCARACNAGYTCNGCNCARTCNACNACNTTYGAYYTNATH TCNTCNAARGTNATHTCNYTNYTNCARCAYGCNCARGAYCCNTCNGTNAARATHGARGGN ATHAAYGAYCCNACNGTNGTNGGNCARATHTAYYTNACNAAYTCNGTNAAYGARTCNGAY ATHTAYAGYGTNGARYTNGARCAYTGYTCNTTYCAYGTNACNGTNATHGAYYTNCARGCN ATHGTNTGYMGNYTNTGYAARATHGAYGAYTGGMGNYTNYTNTGGTCNGTNAAYGAYAAR TTYYTNAARCARTTYCARTCNACNACNACNACNACNCARTTYCAYCCNTTYAGYYTNTAY CCNATGAARTTYGTNCAYGAYYTNAGYTTYTGGGGNGARGARTCNGTN---TCNACNTTY GAYATHTAYGCNYTNTAYGARGCNATHMGNACNATHGCNGGNGAYYTNGTNATHAAYGTN TCNYTNATHGAYGTNTAYGARGAYCCNGARACNAARCARMGNAGYMGNTGYTAYMGNYTN CAYTTYYTNTCNTCNGAYAARTGYYTNCCNTAYGTNACNTCNTGGAARATHCARAGYAAR ATHMGNATGGARGTNGCNMGNAGYYTNGGNGTNCARYTNMGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TTYATHCARYTNGCN GGNGTNTGYGGNTTYGTNGCNTAYATGGTNYTNGCNGTNTCNCARCAYCARAGYYTNACN CCNTAYGGNAAYGGNTTYTAYATHGTNTGYGTNTGGTGYTTYGTNACNTGGAARTGGGGN TTYYTNYTNYTNATHTAYTCNMGNTCNTTYYTNTAYACNTAYATGAGYCCNTCNGAYCCN ACNTCNTAYTCNGARCCNGAYAARTGYGTNATHAARCAYYTNGAYTGGAAYGTNAARYTN AAYTTYAARACNGARACNATHAAYGGNGTNGCNAGYYTNCARTTYGARAARAARAARGAY GARYTNGAYYTNYTNYTNYTNGAYATHMGNGAYYTNMGNATHGARAGYGTNAARYTNCAR GARAAYAAYCARGAYYTNGGNTTYACNATHGAYAAYCCNGCNGARGTNAAYTTYGGNTCN MGNYTNTGYGTNCARYTNCCNATHATHCARGGNAARAGYTTYACNYTNGAYATHAARTAY AGYACNTCNCCNAAYTCNACNGCNYTNTGYTGGATGACNCCNGARCARACNGCNGGNAAR MGNCARCCNTAYYTNTAYAGYCARTGYCARGCNATHCAYGCNMGNAGYYTNTAYCCNTGY CARGAYACNCCNGCNGTNAARTTYACNTAYAARGCNCARGTNGARGCNCCNAGYGARATH ACNGTNYTNATGAGYGCNAAYMGNGGNCARGTNACNCCN------GGNTCNYTNGGNCAY MGNATGACNAGYTTYTCNYTNGAYATHCCNATHCCNAGYTAYYTNYTNGCNATHGTNGCN GGNGAYYTNGARTCNMGNGAYATHGGNCCNMGNTCNAARGTNTGGTCNGARMGNGARYTN GTNGAYMGNGCNGCNTAYGARTTYTCNGARACNGARTCNATGYTNCARGCNGCNGARGAY YTNATGGGNCCNTAYGTNTGGGGNCARTAYGAYYTNYTNGTNYTNCCNCCNTCNTTYCCN TAYGGNGGNATGGARAAYCCNTGYYTNACNTTYGTNACNCCNACNYTNYTNGCNGGNGAY MGNTCNYTNGTNAAYGTNGTNGCNCAYGARATHTCNCAYAGYTGGACNGGNAAYYTNGTN ACNAAYGCNAAYTTYGARCAYTTYTGGYTNAAYGARGGNCAYACNGTNTTYTTYGARMGN AARATHCAYGGNCARYTNTAYGGNGARGCN---TGGAARCARYTNCAYGCNAAYAARGGN TGGYTNGARYTNMGNAARACNATHGARGTNYTNACNGARGAYGGNGAYGCNCCNTAYACN MGNYTNGTNCCNGAYYTNAAYGGNGTNGAYCCNGAYGARGCNTTYTCNAARGTNCCNTAY GARAARGGNTAYGCNYTNYTNCARCAYYTNGARAAYYTNYTNGGNGGNCCNGAYATHTTY AAYGTNTTYYTNMGNGCNTAYATHGARCAYTTYAARTAYACNTCNATHACNACNGARGAY TGGAARAARTTYYTNYTNGGNTAYTTYTCNTCNCCNGARGAYCARGARATHYTNGCNAAY GTNGAYTGGGGNMGNTGGYTNCAYGGNGARGGNGTNCCNCCNTTYGAYGCNAAYTAYGAY YTNAGYYTNGCNCARGCNAGYMGNGAYYTNAGYCARMGNTGGATHAAYGCN------AGY AAYGARGARCCNTTYTCNCCNGCNGAYATHCARAAYATGAGYAGYGAYYTNGTNAAYGAY TTYYTNTCNCAYYTNYTNCARGCNCARCCNCCNATHTCNYTNTCNAARGTNCARMGNYTN GARACNATHTAYCAYTTYCAYGGNGTNAAYAAYTCNGARATHMGNTTYACNTGGYTNCAR YTNTGYATHCARGTNCARTGGGCNGAYGCNATHCARCAYGTNYTNAAYTTYGTNAAYGAR CARGGNMGNATGAARTTYGTNYTNCCNYTNTAYMGNTCNATGAGYMGNTGGGARGARGGN MGNCCNMGNGCNYTNGARAAYTTYGCNAAYCAYMGNACNGARATGCAYAGYACNACNMGN GARAARGTNGARAAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TTYACNTCNYTNMGNGCNYTNATHCCNCAYYTNGAR GGNGARAARYTNAGYAARGCNGCNATHYTNCARCARAGYATHGAYTAYATHACNAGYYTN GARAARGAYAARAGYMGNYTNCARATGCARTTYGARMGNTCNACNMGNYTNYTNGCNGAR YTNGGNCARCARGAYMGNGTNYTNGTNGAYTCNTTYGTNACNAAYACNCCNCCNCCNTCN AARMGNAARAARMGNGAYACNGARTCNTCNGAYGARGGNGTNGGNTCNYTNTCNGAYGCN TCNGAYGAYTGYGGNACNGAYYTNMGNCARAARAAYGARGCNYTNMGNCAYCARATGGAY MGNGARAARCARMGNGGNGAYTCNYTNGARGARGARAAYMGNAGYYTNMGNAAYYTNATH TTYYTNATGCARAARCAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNATGGAYAAYCAYGAR GARATHYTNGAYGCNYTNACNGCNTTYGGNAARAAYCCNAAYCCNCARGARATHCCNTCN GTNYTNGARCARTAYYTNAAYTCNGTNGCNAARAAYGGNGARACNYTNTTYCCNTGGTCN CARYTNAARCCNYTNATHYTNMGNAARATGGARYTNGTNATHYTNGARYTNMGNMGNAAY YTNGCNTCNGARAAYATHCCNACNMGNCCNAAYGTNGARAAYGTNMGNTTYGAYGTNATH CAYGCNMGNATHATHGAYTCNYTNCAYAARTTYAAYGGNGCNCCNTTYACNATHCARMGN YTNTGYGARYTNYTNATHGAYCCNAARMGNCAYTAYAARMGNAGYGAYAARTTYATGMGN GGNYTNGARAARAAYGTNYTNGTNGTNAGYACNGTNGAYCCNTTYGGNMGNAARGTNGTN TCNGARYTNGGNAGYAARCCNGTNYTNAAYGGNATHYTN---GAYATHAAYGGNTCN--- TAYCCNCCNMGNGAYACNGCNYTNAGYGTNCCNYTNCCNCCNGTNCCNGGNTGGGTNAAY ACN------GCNGCNGCNAAYMGNACNATGGCNACNGGNGCNTCNGCNGTNGAYGCNATH AAYAARACNGGNAGYGGNAAYAGYYTNGAYGCNYTNGGNAARGAYTCNGAYGGNGTNTCN AAYAGYYTNGCN------GTNTCNGTNTTYTCNGAYCARGGNGAY---CCNYTNGCNGTN CARTCNGARGARGTNGTNGARGARACNGTNGTNACNATGGAYACNGGNGARGTNAGYTCN GTNGTNACNGAYGGNGGNGARTCNYTNGCNGAYMGNGAYATGGARGGNGAR------YTN GGNGAYGAYMGNGAYGCNTCNTCNTTYTCNTCNTCNTCNTCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATHAGYGAYACNYTNYTNTAYTAYAGYCARATHGTNYTNTAYATHGGNYTNTGY GGNATHATHAGYATHYTNGGNATHATHGCNAAYATHYTNAAYATHATHGTNTTYATHMGN CARGGNYTNAARGAYAGYAGYACNGCNAGYYTNYTNTCNYTNTCNATHTCNGAYYTNYTN GGNYTNGTNTTYYTNYTNTGGACNTCNGTNTGYTTYYTNTTYATGTAYATGAAYYTNGAY YTNCCNTTYGAYATHGTNAGYGTNYTNGTNGTNACNGCNGTNMGNCCNCAYYTNACNTTY GARCARATHTCNGGNTGGYTNACNGTNTAYATHACNTTYGARMGNTGYATGTGYGTNGTN TTYCCNTTYAARGTNTTYAAYACNATGGTNYTNAGYYTNTAYCCNGGNAAYGARGGNTAY ACNATHTCNYTNCCNTCNMGNAAYAGYGCNGARTCNGARACNATGAARYTNCCNTAYGAR GARTCNGARATHYTNGARTAYGTNGAYGCNGCNCARYTNCCNCCNTTYYTNYTNGAYYTN YTNGARAARGCNAAYATG------TTYTAYAGYGGNTGYATHATHGTNGARGTNMGNGAY TTYMGNMGNTCNACNATHGGNTCNTAYGAYAGYCAYTAYGTNYTNYTNMGNCCNTCNTCN CARTCNATHYTNMGNGAYATHACNGCNATGAGYTGYGAYGGNCAYAGYTGGACNCARGAY GAYYTNYTNCAYYTNGARAGYGARYTNYTNYTNGCNACNGARGARCCNYTNTGYYTNGAY CCNTCNCCNGCNGTNATGTAYGTNGARAAYGCNYTNCARTAYCARGARAARTTYYTNAAY GAYCCNGCNYTNAARMGNTCNGTNAARAARTAYACNCARGTNGCNACNAAYMGNAARMGN AARYTNACNCAYTCNGTNGCNCCNGAYAAYATGMGNYTNCAYGAYTTYGTNACNMGNAAR AARGGNAARACNAGYYTNTCNAARACNMGNATGATHGTNGAYTCNTTYAARCARACNTCN GAYCCNGCNYTNACNMGNCCNGARTCNATHGAYGTNAARAARTAYGCNAARMGNCCNGAR GARCCNAGYACNAGYGGNATGATHTTYGTNGARGARCAYACNATGGARMGNGAYCCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TAYMGNTTYTAYCAYTGGGAYYTNATHGAYACN TTYGTNTAYTTYAGYCAYTAYTTYATHACNATHCCNCCNGCNGCNTGGATHMGNGCNGCN CAYAARAAYGGNGTNCARATHYTNGGNACNYTNATHACNGARTGGGARGAYGGNTCNGAR ATHTGYAARGARYTNYTNAARTCNMGNGAYACNATHGAYYTNGTNGCNATHAARYTNGCN GAYATHGCNTCNGTNYTNGGNTTYGAYGGNTGGYTNGTNAAYATHGARAAYGCNATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNACNTCNAARGARGCNCCNTCNACNTCNGCNTCN ACNTCN------------GCNTCNGCNTCNTCNTCNTCNTCNCCNCARAARMGNAARAGY ACNGARTCNGAYGARGARYTNAARCARGCNATHAARMGNATHAARMGNCARGAYGARGAR MGNATGAARATGCARGTNYTNGTNTCNAAYTTYTCNGARGARCARYTNAAYMGNTAYGAR ATGTAYMGNMGNGCNACNTTYCCNMGNGCNTCNATHAARMGNYTNATGCARAGYATHACN GGNTCNACNGTNTCNCARAAYGTNGTNATHGCNATGTCNGGNATHGCNAARGTNTTYGTN GGNGARGTNYTNGARACNGCNYTNGAYGTNAGYGAR------------------------ ------------------------------------------------------------ ---------------------------------ATGGCNTCNAARAARGTNAAYGTNCCN AGYGCNAAYAARAGYGGNGCNYTNCCNGCNATGATGACNGGNGAYCCNAARACNATGAGY AARGGNYTNATHGTNYTNCARGARTGGTGGGGNATGAAYGARCARATHCARAAYTGYGGN AARGAYYTNTGY---GGNCARGGNCARATGGTNACNYTNGTNCCNGAYYTNTAYMGNGGN AARGTNACNAAYGAYAAYGARGARGCNGGNCAYTTYATGGGNGAYYTNGAYTGGAARGGN GCNGTNGAYGAYATHCARGCNTGYGCNAARTTYYTNAARAGYAAYGGNGTNAARAARGTN GCNGTNGTNGGNTTYTGYATGGGNGGNGCNYTNAGYATGGCNGCNGCNGCNYTNGTNCCN GARGTNGAYGCNGCNGTNCCNTTYTAYGGNATHCCNTCNTCNGGNYTNTGYGAYGTNACN ACNATHAARATHCCNATGCARTGYCAYTTYGCNYTNAAYGAYGCNACNTCNGGNTTYGCN TCNCCNGCNGARTGGAARCCNYTNAARGARAARYTNGARGGNAARYTNGCNAARYTNGAR TTYTAYGARTAYGAYGCNGGNCAYGCNTTYACNAAYACNACNGGNCCNAAYTAYGAYAAR GGNCAYTGYGAYYTNGCNTTYTCNMGNATGTTYAARTTYYTNAAYAAYCAYYTN---YTN TCNTCNGTNATHGARATGGGNYTNAARGTNACNCCNCAYGCNAARGARGARACNTGGACN ATHGTNAARGARYTNMGNAAYAARGAYCCNGTNGTNGGNACNTGGGGNMGNYTNAARGAY GTNAAYTCNTCNCAYGCNYTNGAYTAYGGNTGGAGYAGYTCNYTNTGYTGYCARGARATH TAYAAYACNYTNCAYATHGAYACNAARAAYGTNYTNTTYAGYCARAARAARCARTCNGTN CCNTTYTAYGCNTCNGGNYTNGGNATHYTNGARCCNATHMGNGGNGGNCCNAAYGCNGAR AARAGYCARCAYYTNGTNGCNACNACNCCNGCNYTNYTNGAYACNAGYAARCCNGARGAR TCN------AARAARTCNYTNGAYATHCCNCCNGTNGAYTTYGAYTGGGGNTCNAGYGGN YTNACNAAYCCNYTNAARGTNTTYAARAAYGAYAGYTTYAAYAAYGGNYTNACNTCNYTN GARCCNTTYTCNGAYATGYTNCAYAARAAYATHGARCCNTCNAARGARYTNAGYAGYGAR GCNAARAGYATHYTNTCNAARATHCCNAAYYTNAAYTTYATGMGNTCNAAYGTNYTNATG TTYCCNATHAAR------------------------------------------------ ------------------------------------------------------------ ------GAYCARYTNATHTCNTCNTGGTCNATHGARGARTGGTGGGAYGTNMGNGCNGCN YTNATHGARYTNATGAARAARGCNACNCARCARGAYTGGACNMGNGARCARATHCAYAAR GARYTNGAYTCNGTNAAYGAYGCNTAYAARTCNGCNATHTCNGARGCNATHTGYATHCAY TCNAARTCNATGAARMGNAARYTNYTNCARAAYACNGCNTCNATHTCNNNNGCNGTNYTN TCNGAYTTYGAYTGGAARYTNCARYTNGCNYTNTCNAGY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNCAYGGNGAYCAYGGNAARCCNYTNGARTTYTCNTCNGAR ATHCAYAAYAARGAYCAYATHATHGARCAYYTNCARMGNCARATHTCNACNAARCCNAAR GARCARATGACNGAYGARGARYTNGARTTYCAYTAYTTYAARYTNCAYGAYTAYGAYAAY AAYAAYAARYTNGAYGGNGTNGARATHGGNAARGCNYTNACNCAYTTYCAYGAYGAYGAR GCNGAYATHGCNAARAARGAR---------------------CCNCCNAARGTNTTYGGN GAYGARGARATHTCNAAYATHGTNGAYTCNGTNATHGARGARAAYGAYAGYAAYAARGAY GGNTAYATHGARTAYTTYGARTTYAARACNAARCARGCNGARATGAARAARTCNAGY--- ---------------AAYGCNCARCCNCCNATGGGNMGNGGNMGNACNAGYGAYTCNGAY AGYGAYMGNTCNTCNAARAARAARAARAARGARMGNMGNMGNMGNACNMGNTCNMGNTCN AAYAGYTCNGCNGAYTCNAGYMGNTAYTCNAGYTCNMGNAGYAARAARAGYAARAARAGY AGYAARCAYTCNMGNMGNMGNTCNCCNGAYAGYCCNGAYMGNGGNMGNGGNGGNAARGAY CARTCNMGNMGNTCNMGNTCNMGNTCNCCNGARMGNAGYAARACNTCNMGNAARMGNTCN CAYTCNGGNTCNAGYAGYMGNMGNTCNMGNTCNGGNTCNMGNGGNTAYGGNGGNMGNMGN TCNMGNTCNMGNTCNAAYTCNMGNAGYMGNMGNTCNGGNTCNMGNGGNCAYAGYAGYAGY MGNACNAARAGYGAYMGNGAYCCNCAYCAYMGNMGNAAYCARMGNTCNMGNTCNAARTCN AGYTCNACNGAYMGNTCNMGNCARGCNAGY------------------------------ ------------------CCNGARMGNTAYGARAAYGAYCARTCNCARGCNATGACNTCN TCNGARAARTCNGARYTNMGNATGMGNAARGCNYTNCARGCNGCNGCNYTNGCNGAYGAR ------MGNYTNAARACNYTNMGNGAYCARGGNTCNTCN------------GGNTCNTCN TCNCCNTCNACNCAYAAYGCNGCNGCNATHCARTCNAARGAYTTYGCNGAYACNGTNGCN GCNATHGAYTCNGGNMGNTTYGTNCARTCNTCNTTYAARTCNGGNGGNATHGTNGTNAAR GARGARAARCCNGAYCCN---YTNATGTCNAGYCAYGAYGAYGCNATHTTYGGNTCNYTN TCNTCNGTNGGNTTYACNATHAARCCNGAYYTNGAYACNCARCCNGTNTCNYTNGAYGCN GAYTCNATHATGCAYCCNTCNYTNTTYTGYAAYGTNGARGARAARATGGARMGNTGGATH GAYMGNYTNTCNCAYYTNMGNAARMGNAARATHGARGGNGARGCNATG------------ ------------TGYATHGTNYTNYTNCCNAGYTAYGCNTCNCAYYTNCCNAARGARGGN GARACNYTNACNGGNTAYAARTTYACNGTNGGNTTYGGNGGNAARGGNGCNAAYCARTGY ATHACNGCNGTNAAYYTNGGNGCNCARGTNGCNATGGTNGGNAARYTNGGNGAYGAYACN TTYGGNAARGAYTAYATGATGAAYATGYTNACNAAYAAYGTNAAYTGYGARCAYYTNAAR ATHGTNCCNAARGTNTCNAAYGGNGTNGCNTCNATHCARGTNGCNGAYAGYGGNGCNAAY TGYATHGTNATHGTNCCNGGNGCNAAYAGYTAYYTNACNGTNGARGAYGTNAAYYTNGCN GARGAYACNATHAARAAYTGYCARGTNYTNATHTGYCARAAYGARATHCCNCARCAYATH TCNYTNTCNGCNGTNAARATGGCNNNNAARCAYAAYGTNCARGTNATHTAYAAYCCNGCN CCNGCNTCNTCNGARYTNYTNTCNGARYTNTTYTCNYTNGCNGAYTAYTTYTGYCCNAAY GARACNGARGCNGARATHYTNACNTGYAGYCCNGTNAARTCNGTNAARGAYGCNTTYGAR GCNTGYMGNGTNYTNCARATGGARAARGGNTGYAARTCNGTNATHATHACNYTNGGNGAR AARGGNGCNGTNTTYAARGAYTGYTCNTCNAGYGARGCNGTNCAYATHCCNACNTTYCCN GTNAARGCNGTNGAYACNACNATGTCNTTYCCNGGNMGNACNCCNATGGCNATGCCNGGN GGNATGCCNGGNATGCCNCCNMGNATGATGACNACNCCNGGNTAYGCNTTYACNTCNATG GGNATGACNMGNATGAAYCCNATGATGCCNATGCARATGGGNATGATGACNCCNATGATG CARCCNATGATG---CARCCNCARATGCARATGCARCCNCARCARCARCAYATGAARCAR AAYCCNAARTTYGTNCCNCARGARATHCCNAARACNGAYCCNAARGGNGARAARCCNCCN GTNACNACNGTNTTYGTNGGNAAYATHAGYGAYMGNGCNCCNGAYATGATGATHAARCAR ATGYTNCARMGNTGYGGNAAYGTNYTNAGYTGGAARMGNGTNCARGGNGCNTCNGGNAAR YTNCARGCNTTYGGNTTYTGYGARTAYGARGAYCCNGARGCNACNYTNMGNTGYATHMGN YTNYTNAAYGAYTGGCCNATHTCNAAYAARAAYYTNGTNGTNAARGTNGAYGCNAARACN AARACNYTNYTNGAYGARTAYMGNAARAARAARAARGGNAGYGARGARGGNGAY---AAR AARGAYCARGARACNAGYGAYAARAARGARAARGGNGARGARGARAAYGGNGARGGNAAR GARCARGCNGARGAYGGNAARGARGARTCNGARGARAARGARGGNGAYYTNGAYGARAAY ACNCARMGNGARGAYMGNYTNGCNCARGCNGGNYTNGARGCNATHATGAARGARTAYGCN TTYGARYTNGCNAARGARCCNGCNAARCCNACNGAYGGNGGNGAYCARGAYAARGARAAR CARATGCCNAARAARGAYAARGARGCNTTYACNCAYGCNAARGAYACNGGNTTYGAYGAY ATGGARATGGARGAYGARAARMGNCARATHATHAAYMGNGARATHAAYAARTTYMGNGAY MGNCAYAARGAYGCNGAYGARGARAARGARAARGAYAAYMGNGARAARGARMGNAGYYTN GCNMGNGARMGNGAYMGNMGNCARGARGARAARMGNCAYMGNGARMGNYTNGARAARYTN MGNGARCAR------------------MGNGARMGNGARMGNGARMGNCCNCCNGCN--- GCNMGNGTNTCNMGNTCNAARTCNMGNTCNGTNTCNCCNGTNCCNTCNMGNTCNMGNMGN MGNTCNMGNTCN------------MGNGARMGNACNAGYMGNGAYMGNTCNMGNGARMGN MGNAARGARMGNGARATHGARGARGARGARGARYTNTAYGARMGNMGNAARYTNGARAAR AARYTNMGNGARAARGARGCNGCNTAYCARGARMGNYTNAARAAYTGGGARGGNMGNGAR MGNAARAARACNMGNGARTAYGARAARGARAAYGARMGNGARGAYGARMGNAARGARGAR GARACNMGNGARGGNMGNMGNYTNAARGARTTYYTNGARGAYTAYGAYGAYYTNMGNGAY GAYCCNAARTTYTAYAARGGNAGYGCNYTNYTNMGNMGNCARAARGARMGNGARAARGAR AARGARYTNGAYAAYMGNGAYMGNCARMGNGARAARGARGARTTYGARGARATHAARMGN AARYTNTTYGAYGARGGNCAYCCNGAYGCNGARACNGARGTNGCNMGNATGGARMGNGAR MGNGARGARCAYYTNCARCCNMGNYTNCAYYTNCARGARYTNAARCARCCNCCNCARCCN GTNGCNAAYCAYGARTCNGARTCNGAYGAYGARCCNYTNCCNTCNGGNMGN------TCN GARTCNMGNCARCCNCCNTCNCCNAARCAYCCNGARCAYAAYCARTCNMGNAAYGGNACN CAYAAYCARCARCARAAYYTN---------GTNATHGAYCAYCARCARCARCARCAYMGN CCNTCNCCNTCNYTNTCNACNTCNCCNATHTCNACNGAYTCNMGNGTN---AGYAGYGCN CCN--------------------------------------------------------- ------------------------------------------------------------ ------------GCNCCNGGNATHAGYCCNGAYTCNTCNAGYYTNCCNGGNGCNACNAAY GTNYTNGAYGGNAARMGNAARAARYTNACNGTNGGNGAYGTNTTYAAYCARGAYGAYGAY GAYAGYAAYGARCCNAARAARMGNAARYTNATHCCNYTNGAYTAYGAYGARGAYAARTCN ACNCCNACNGAYAARAARGGNGCNACNGCNGARGARAARMGNCARAARATHAARCARYTN ATHGARAAYATHCCNACNGCNAARGAYGARYTNTAYGCNTAYACNGTNGAYTGGGARATH GTNGAYCARGCNYTNATGGAYAARMGNATHAARCCNTGGGTNACNAARAARATHGTNGAR TAYATHGGNGARGARGARCCNACNYTNACNGARTTYATHTGYCARAARGTNATHGCNMGN AGYACNCCNCARAGYATHCARAAYGAYGTNGCNATGATHYTNGAYGARGARGCNGARGTN TTYGTNGTNAARATGTGGMGNYTNYTNGTNTAYGARACNGARGCNAARAARATGGGNYTN GTNAARYTNGTNAARGARGARTAYATHAARCARTCNMGNCAR---TGGCCNCARGARGGN AARCAYATHYTNGCNCAYTAYGAYGAYGARACNGTNGTNGTNTAYCARGCNTAYAAYCCN AARATHGCNAGYTAYGCNGTNAARTAYCARCARTTYGGNGGNCCNGAYTTYAARTAYGAR MGNATGTCNTGGATHAARACNAAYTTYATGTGGATGATGTAYMGNTGYGGNTGGGCNCAR AARCAYAAYCARGARMGNGTNYTNGCNGTNTGGYTNACNMGNCARGGNTTYGARAAYATH YTNGCNGTNGCNAARTCNGGNAARGGNGGNGAYCARGARTCNMGNAARTCNGAY------ GARGTNMGNATHCARTGGGAYCCNGAYCAYACNCCNAARGGNGAR---AGYYTNAARMGN MGNGCNATHCARYTNGGNYTNMGNGGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CAYAGYTCNAGYAGYAGYAAYGCNCAYACN AARGCNAGYTCNYTNGAYATGGARTGGGARCAYGARGCNGGNATGTCNCCNAAYAARMGN MGNCARCCNGTNTCNGTNTCNGARGAYAAYTGGTCNAARACNTCNACNGCNAGYCCNYTN CAYTCNAGYGAYYTNGARTGGGAYCCNGAYTTYGTNTCNGCNGAYGAYAAYGARMGNYTN CARYTNATH--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GGNMGNTCNCCNGTNGARGCNMGNGGNGGNCARYTNGARATHGCNGGNGTNGTNGTNGGN CARTGGGGNCCNAAYATGTCNGGNMGNMGNGGNMGNGGNGGNCARYTNTCNCCNCARATH ATGTCNGTNGGNCARMGNGGNATGTAYAAYGGNMGNGGNTTYATGCCNACNMGNGGNGCN TAYCCNGGNAAYTAYGGNMGNGGNMGNGGNTCNCARMGNCCNGTNMGNATHGTNGCNMGN CCNGGN---------GAYAAYAAYATHCCNCCNYTNGARGAYATGACNGAYGTNYTNCAR AARGCNGARYTNATHMGNGARCARMGNTAYGGNTCNMGNGGNCARACNCARACNTCNTCN CARAARGAYGAYGCNAARAARMGNGCNAARGTNACNAARAARAAYGTNGARAAYATHGGN GTN---------------------------ACNACNGCNAARGARACNCCNGARAGYGAR AARTCNAAYAARGARGAYACN--------------------------------------- AAYAAYGTNAARGCNACNACNCCNAGYMGNCARGGNATGTTYGGNGGNATGAARAARGGN TTYYTNTTY---GGNGCNCCNAGYAARCARTCNACNAARGCNTCNTCNAAYACNAGY--- ---------------AARGARCARAGYGARGAYCARAARCCNAAYACNGARAARAGYACN ACNGCNAARCCNACNCARAARGARGARATHCCNTTYATHACNCCNTCNGTNAARACNGAR TCNGGNYTNACNTTYAAYGARGTNCARCARGCNATGTCNGARGCNAARGGNYTNYTNGAY AAYCARGARTGGATHACNGAYGAYTTYYTNAAYAARATHGARAARAAYGARACNYTNYTN CARMGNTTYAGYGAYCCNCARTTYATGTCNGCNYTNCARGARTTYCARACNAAYCCNCAR GCNGCNATGGARAARTAYAARGGNAAYCAYGARGTNGARAARTTYYTNYTNGARTTYTGY GGNYTNYTNGGNGAYCAYYTNACNAARYTNGGNACNGGNGCNGARAAYCCNCARTCNGGN CARAGYCARAARTCNAAYCCNCAR------------------------------------ ------CCNGTNGTNAAYAARCCNAARGTNCARAAYGARGCNYTNCARTCNAARACNCCN AARATHGTNGARATHGGNAAYGAY------------GAYGARAARTCNACNAARTCNYTN AARTCNGARTCNAGYAAYTCNTCNAAYGCNYTNAARACNGCNTCNGGNCCNGAYGTNAAY AGYGAY------------------------------------------TCNTAYATHMGN ATHCAYGAYTCNCARAAYGGNGCNGCNATHAARGARATHGAY---------------CAR AARGAYGAYGAYGCNGTNCARGARGTNYTNAAYGAYCCNAARGTNATGGARACNYTNATG GAYCCNAARATHATGGCNYTNATHAARACNYTNMGNGARGAYCCNGARGARGGNCARMGN ATHATHGAYAARGCNGAYYTNGAYYTNAARGARAARGTNMGNTTYYTNGTNTCNMGNGGN YTNYTNCARTTYCAR---AGYCARAAYMGNTCNMGNCCNACNAAYGTNCCNTCNYTNGTN YTNCARGAYCAYGARAAYGARATHGTNTTYCARACNYTNGGNMGNYTNTGYGTNACNYTN GCNACNGGNGTNGTNCARYTNTAYYTNGCNGAYCARAGYGAYCAYGCNMGNTGGAAYAAR MGNAGYTGYGGNGTNGCNTGYTTYGTNAARGAYAAYTCNAARMGNTCNTTYTTYATHMGN GTNTTYGAYATHAARAARCARYTNATGATHTGGGARCARGARATHTAYAAYCARTTYGTN TAYAARACNCCNMGNGARTAYTTYCAYACNTTYGARGCNCAYAAYTGYCARGCNGGNYTN AAYTTYGCNCAYGARGAYGARGCNATGAARTTYAARAARGCNGTNGARGGNAARYTNAAY GARMGNAARCARAARAARATGGARMGNMGNAARTCNTCNATHTCNAAYAARCAYGGNATG GAYCARGGNCCNGGNGCNAAYACN------------CCNCARMGNATG---GGNGGNACN AAYGCNACNCCNACNCARACNGTNACNGTNGAYGTNAAYMGNYTNAAYAAY------AAY AAYCARAARAARGARAARGAYAARAARAAR------GAYGGNAARAARAARYTNACNAAR GCNGAYATHGGNACNCCNTCNAAYTTYGTNCAYATHAGYCAYGTNGGNTGGGAYCCNGAY AARGGNTTYGAYATGAAYAAYYTNGARCCNGAYATGCARACNYTNTTYCARTCNGTNGGN ATHAARCCNGARGAYAARGTNGAYAARGAYACNGTNGAYTTYATHTAYGAYTTYGTNGAR AARMGNGGNGGNATGGARGCNTTYAGYAARGARYTNMGNAGYAAY------GCNAGYMGN CCNCCNCCNCCNCCNGCNAAYAAYATGGCNMGNACNGCNCARCCNCCNCCNCCNCCNGCN MGNTCNCCNGGNGGNCCNCCNCCNCCNCARMGNGGNGGNGCNCCNCCNCCNCCNCCNCCN TCNMGNGGNCCNCCNCCNACN---ATGMGNGGNGCNYTNCCNCCNCCNCCNCCNTCNMGN GCNATGCCNACNCCNCCNMGNGCNCCNGCNTCNTCNCCNCCNCCNCCNCCNCCNTCNTCN GTNCCNCCNYTNCCNCCNATGGGNGGN------------GGNTCNGCNGGNGTNCARGCN GCNCCNCCN------------CCNCCNCCNCCNTCNGGNGGNCCNCCNCCNCCNCCNCCN CCNCCNCCNCCNCCNATGGCNTCNYTNTTYGGNGARCAYMGNYTNYTNACNAARAARGTN TTYGAYGARATHTAYATHGCNGAYAARGAYMGNGAYAAYCAYAAYACNGTNYTNGCNAAR GARGCNYTNGARGGNAARGTNGTNTGYYTNTTYTTYTCNGCNTCNTGGTGYACNCCNTGY CARCAYTTYGTNCCNACNYTNAARGARGTNTAYTCNGARYTNGTNCAYMGNAAYATHCCN YTNGARGTNGTNTTYYTNAGYTTYGAYAARACNGARGARGARATGATGAAYTAYTAYCAR GARAARCAYGGNGAYTGGYTNTCNGTNAARTTYGGNGAYACNYTNAARCARGARYTNGCN GARMGNTAYTCNATHAGYGTNATHCCNAARYTNATHGTNATHCARCCNGAYGGNGARGTN ATHAGYAAYAARGGNMGNAARGAYGTNCARGAYMGNGGNGTNGTNTGYATGMGNGCNTGG CAR--------------------------------------------------------- ---------MGNMGNGTNGARYTNYTNACNYTNYTNCARYTNTTYAAYATGATHYTNTGG ATHGTNGAYGTNCAYTAYAARTTYATGCCNGTNTCNATHYTNCCNGCNYTNATGGTNTTY GTNGGNYTNYTNGGNGGNGCNTCNTAYGTNAAYATHTTYTAYTCNYTNATHCAYGAYGAR AARTAYCCNAAYGARGAYAARGARTTYTGYATHAAYYTNACNGGNYTNTTYATHAAYTCN GGNATHYTNYTNGGNACNGGN------GTNGCNGGNATGMGNAARCCNTAYAARGAYMGN CARGAYGTNTTYGAYGTNAARGAYYTNAAYTCNAARGARCCNTTYTCNCARTTYACNACN TGGTTYGARGARGCNAARTCNACNCCNGGNATHATHGARGCNAAYGCNATGGCNYTNGCN ACNGCNACNMGNGAYGGNGTNCCNTCNGTNMGNATGGTNYTNATGAARGGNYTNAGYAAR GAYGGNATHGAYTTYTAYACNAAYTAYCAYAGYCARAARGCNCARAAYYTNGTNGARAAY CCNCARTGYAGYYTNATGTTYTAYTGGGARTCNYTNAAYAARTCNGTNMGNATHGARGGN AARGTNGARAARYTNTCNCARGARCARTCNGARAAYTAYTTYCAYTCNMGNCCNMGNTCN AGYCARATHGGNGCNTGYGTNAGYGARMGN---CARAGYTCNGCNATHTCNTCNMGNGAR GTNYTNGAYAARAARAARGARCAYYTNGARAGYCARTAYAGYGAYGARAGYYTNACNATH CCNAARCCNGAYTAYTGGGGNGGNTTYMGNGTNGTNCCNCAYMGNTAYGARTTYTGGCAR GGNCARACNAAYMGNATHCAYGAYMGNATHGTNTTYMGNAARCCNCARACNGGNGARAGY ATHGAYGCNTCNGTNACNTTYCARGGNAAYGAYGGNTGGGTNTAYGARMGNYTNCARCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNAARAAYGGNCARTAYGARGCNYTNTAYAAYGGNGTNCCNATHYTNTGY YTNCCNYTNTTYTGGGAYCARYTNTAYAAYGCNGARTGYGCNMGNGCNAARGGNTAYGGN YTNAARGCNGAYATGMGNTTYGTNTCNGTNGARGAYYTNTCNGARATGGTNMGNGARYTN GTNACNAAYMGNACNTAYAARGAYACNATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AAYTCNTTYTCNTGGATHAARTCNACN GCNTTYGTNACNGGNGTNTGYAGYTGYAGYTTYYTNGGNGCNATGATHTGGAARTAYGAR AAYGTNMGNCARATHTAYAARGAYATGGCNTCNGARAAR---------GCNTCNMGNYTN MGNTTYTTYAAYGARAARGCNTTYGGNTTYMGNAARCAYYTNAAYGCNATHTGGGARAAY YTNGAYTCNTCNGCNAARYTNACNTTYGGNATHATHGCNGCNAAYGTNGCNGTNTGGATH YTNTGGAARGTNCCNMGNYTNCARCCNGGNATGGTNMGNTAYTTYTCNTCNTCNGCNGCN CAYCCNMGNYTNTCNATGGTNYTNAGYAGYTTYAGYCAYATHAGYTTYYTNCAYYTNGTN GTNAAYATGTAYGTNYTNYTNTCNTTYGCNCCNGTNGCNACNAARACNTTYGGNCAYGAR CARTTYTCNGCNTTYTAYATHAGYGCNGGNACNATGTCNGCNTTYGCNAGYATHYTNTGY CARMGNYTNYTNAARMGNCCNYTNTCNATGTCNGTNGGNGCNTCNGGNGCNATHATGGGN YTNYTNGGNGTNACNGGNGTNYTNTAYCCNACNGCNCARYTNCARGTNGCNTTYGTNTCN GARATGTTYCCNCAYTCNTTYTCNGCNGAYTCNGGNATHAARGCNATHGTNYTNTTYGAY YTNATHGGNYTNTTYATGGGNTGGAARGTNYTNGAYCAYGCNGGNCAYYTNGGNGGNATG YTNTTYGGNATHYTNTAYGCNAARTAYGGNAGYAARYTNATHTGGGGNAAYMGNGAYTCN GTNATHAARGTNTGGCAYGAYATHMGNGGNAARCCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYACNYTNAAYACNGAYCARMGNGCN GTNAARMGNGARTTYTTYAAYCARCARYTNAARGCNCAYGARGCNGARGTNGARGCNYTN AARMGNCARMGNGARGAYMGNAARGTNAARGARGARAARGARGTNGTNGCNCARYTNMGN CARGARATGGTNCCNAARGCNACNACNATHAARAARTAYAARYTNGTNACNCCNCARCCN AGYGAYAAR--------------------------------------------------- ------------------------------GAYGAYMGNCAYGGNGGNGTNCCNATGGGN GTNCCNAAYGARTAYTGYGAYGAYGGNAARCAYTTYYTNAAYATHGAYTGGGAYCCNGAR TCNACNGARGARTAYACNTGY---AAYGGNGARMGNAAYCCNGCNAAYATHACNGARYTN ---------ACNCCNTAYCAYTGYGAYYTNGARACNGARATGCCNTGGCAYATHTGYTAY AAYAARAGYATHACNTAYGAYGARGAYYTNCCNACNAGYGGNCCNCAYMGNCCNATHTGG CCNAARTAYGGNGARTAYMGNTAYGTNCCNCCNCARMGNTGGYTNCAYTCNYTNGARCAY GGNGCNATHATHTTYYTNTAYCAYCCNTGYGCNTAYAARTAYCARATHAAYAARYTNMGN GCNGTNGCNGARAGYTGYYTNMGNMGNCAYATHATHAGYCCNTCNAARMGNATHCCNAGY AAYMGNATGTTYGCNGTNYTNTCNTGGGGNTGYAARYTNTAYATGAGYGARATGGAYGTN ACNMGNACNGTNGARTTYGTNAARGAYMGNGCNGTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARAGYCARATHGAYGAYGARYTNYTNCCNGAYYTNGAYGAYAGYGTNYTNCARACNGCN MGNATHMGNAARAAYCARGTNTCNAARTGYATHYTNGARGCNCARAAYATHGTNTCNAAY TCNGTNAARTAYTAYAGYCAYGTNACNGTNGARAGYGARCCNYTNGARTAYGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNYTNYTN ACNGGNAARCCNCAYACNMGNCAYAARGGNCCNAAYATHYTNAARGGNAAYTCNYTNGCN TCNAARATGTTYTCNGAYTCNCCNYTNYTNTCNTCNAGYACNAAYGGNTCNTCNTCNGAY GGNYTNGAYGGNGAYMGNTCNTGGGARAARCAYACNAAYACNTTYAARCCNCCNGTNCCN GTNGGNAAYGGNGAYCARMGNCAYGGNGAYAARTCNGAY---GARAAYGCNAARAARAAY TCNAGYTCNAGYYTNTCNGGNGGNAAYCARCCNGGNAGYATGGARACNYTNAARAAYATG YTNTTYAARYTNCARAARGARGARACNAGYAAYACNAAYACNGAYAGYGARAARATHTCN GGNYTNCCNGCNYTNCARGAYTAYGAYTTYCARACNGARCCNGGNGGNCAYTCNYTNGAR AARGCNYTNCAYCAYYTNGAYMGN------------------------------------ ------GTNGTNATHCARAARYTNGARGAYGARTCNGCNTTYCCNTTYGCNGGNMGNGAR GGNCARGTNGCNTGYAGYGTNTCNAAYAARGTNTAYGTNTTYGGNGGNGTNGARCARGGN CARGGNGANGARCCNAARGARACNAAYGARYTNYTNGTNTTYGAYYTNGCNGCNCAYAAR TGGTCNAARCCNGTNGTNCAYGGNTCNCCNCCNCCNGCNMGNTCNGCNGCNTCNYTNGTN GCNGTNGAYACNAARYTNTAYYTNTTYGGNGGNYTNAGYCAYATHTGYGGNTGGTTYGAY GAYGTNCAYACNTTYGAYACNGTNACNAGYACNTGGTCNATHYTNGARACNGARGGNATG AARCCNMGNGCNMGNGAYAARYTNCARGCNGTNGCNATHGAYACNAAYATHTAYTAYTTY GGNGGNTTYGGNCCNAARTCNGAYGARGCNGARGTNGAYGAYYTNGGNAAYGAYGAYGAY GARTAY---GARGAYGARGARGAYATHCCNGARAGYCAYGARCARGAYGGNGCNGARTTY GGNTGGTTYAAYGAYYTNTGGGTNYTNGAYACNYTNACNYTNAARTGGTTYGARCCNATG CARATGAAYYTNGGNGTNCCNACNCARMGNGCNGCNCAYGGNATGTGYGCNGTNGGNMGN AAYATHGTNATHTTYGGNGGNMGNGAYGTNGARGAYMGNCARAAYGAYGTNCAYGTNTTY AAYATHGAYACNAARAARTGGGAYACNGAYYTNATGYTNAGYGGNCAYTCNCCNGGNCCN MGNTCNTTYCAYACNGTNACNGCNGTNGGNAAYMGNGTNGTNGTNTTYGGNGGNMGNGGN MGNGAYAAYAAYCAYTAYAAYGAYTTYGAYGTNYTNGAYYTNGAYAARMGNGARTGGTCN MGNGCNTCNTCNGARGGNTAYAARCCNCCNGCNMGNGGNCARCAYTGYGCNYTNACNGTN GGNGAYACNTTYYTNATHTTYGGNGGNTCNGGNAAYTTYAGYCCNGARATHATGCARTGY CARACNTTYTTYACNGAYACNTTYTTYATHAARACNAAYTCNTTY---TCNAGYAAYGAY AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNMGNGAYGGNACNAAR GTNATHATHACNGCNGGNAAYGAYGARAAYTTYTGYTCNGARYTNMGNAAYAAYACNGCN ACNATGAARAAYCARGTNGCNAARTTYAAYGAYYTNMGNTTYGTNGGNMGNAGYGGNMGN GGNAARAGYTTYACNYTNACNATHACNGTNTTYACNAAYCCNCCNCARGTNGCNYTNTAY CARAARGCNATHAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARACNYTNGTNGAYCAYCARGTNCAYMGNYTNCCNGTNATHGAYGARAAYTCNGGNAAY GCNYTNTAYATHYTNACNCAYAARMGNATHYTNMGNTTYATGCAYYTNTAYTTYAARGAR YTNCCNCAYCCNGCNTAYATGAARAARTCNATHAARGARYTNGGNATHGGNACNTAYGAR AAYGTNATHACNGCNACNCCNGAYATGACNYTNATHAARGTNYTNAAYYTNTTYTCNGAY CAYMGNATHTCNGCNYTNCCNGTNGTNGAYAAYAAYTCNGGNAARATHATHGGNATHTAY GCNAARTTYGAYGTNATHAAYYTNGCNGCNGARAARACNTAYAAYAAYYTNGAYATHACN YTNAARGAYGCNYTNGAYMGNMGNTTYGAR---AAYCAYCARGCNGGNGARAARGTNGTN TCNTGYCARACNTCNGAYTCNYTNGARGAYGTNGTNGAYAARATHGTNAARGCNGARGTN CAYMGNYTNGTNGTNGTNGAYGARAGYGGNGGNGTNGARGGNATHATHTCNYTNTCNGAY YTNYTNAAYTAYACNGTNYTNMGNCCNATHGARGARGTNTCN------------------ YTNGGNACNCCNYTNCCNGAYYTNGAYGARACNCARGCNACNAARAARCCNATHACNGTN CARGAYYTNACNGCNACNGAYAARGARGGNMGNMGNMGNTTYCAYGGNGCNTTYACNGGN GGNTTYTCNGCNGGNTAYTTYAAYACNGTNGGNTCNAARGARGGNTTYATHCCNTCNTCN TTYATHTCNTCNMGNAGYCARAARAAYGAYGARGGNCARCARTCNMGNCCNGARGAYTTY ATGGAYGAYGARGAYYTNGARGARCAYGGNATHGCNCCNMGNAARTTYACNACNTCNGGN AAYTAYACNTCNGARGARMGNAARMGNAARYTNGARGAYGTNGCNAARCARYTNACNCAR TCNTCNGCNYTNGARTTYGGNGGNGCNTTYAAYGAYYTNGTNGTNCCNGARTAYYTNCCN ATHGGNATHAARYTNYTNAARAARATGGGNTGGMGNGARGGNCARGGNYTNGGNCCNMGN GTNAARMGNAAYACNMGNAARGGNAARAAYAARGAYGGNTCNAARGGNAARAARGTNTAY GGNTGYGCNYTNCCNCCNTCNGAYTCNGAYAGYGAYGAYTCNGAYTCNTAYATHCCNTCN AGYATHAGYGAYYTNACNTTYGCNCCNTCNGAYGTNAGYCCNATHATGYTNAAYACNAAR GAYGAYGTNAARGGNYTNGGNTAYMGNGGNYTNGAYCCNTCNYTNGCNYTNCCNGGNTCN MGNGTNAGYCARTTYGGNAAYCCNATHMGNGGNAARMGNMGNGGNAARGGNATHATGGGN CARGCNTTYGGNYTNGGNGCNYTNGARGAYGAYGAYGAYGAYATHTAYGTNCARGAYAGY YTNTCNAAYTAYGAYYTNACNATGMGNGAYGAYGAYGAYGAYCARGAYGGNAAYTTYGGN TGGACNGCNCCNMGNACNCAYGCNAARCARAARYTNCCNYTNGCNTAYGTNGGNAARYTN YTNGARGGNTTYTGYYTNTCNTCNAARCCNYTNCARTCNMGNAARAARTTYCCNCCNCCN AARYTNYTNGCNGAYTTYAARTCNCAYCAYTGGTCNMGNMGNMGNAARAARGAYGTNGAY ---------------GAYAARCARAAYAARATGACNGCNATHGAYMGNGGNYTNYTNYTN GGNGARAARCCNATHATGAAYTCNGTNTTYGAYYTNGTNGGNTCNAARGAYAARAGYMGN ATGGARTCNGCNAARGARGCNATHGARATGACNAARTCNYTNACNTCNAGYGGNATHCAR CCNGARAARGGN------------------------------------------------ ---------YTNGAYACNGARAARAAYCAYCARTCNAAR---------TTYYTNTCNMGN TTYACNGARGCNGAYACNATHAAYGARGAYAARTCNGTNAARMGNACNTCN--------- ---AAYACNTCNYTNTTYAARGGNAGYYTN------CARCCNTTYYTNAARGAYCCNCCN AARCARGCNMGNTTYGAYCARTAYYTNACNGCNGTNCARCARAARGTNCCNGAYCCNTAY AGYCARGTNTCNAAYCARCARATGACNGARTGGGARAARTCNMGNGARCARGAYGARTTY AGYMGNTCNGCNMGNYTNTTYAARCCNATGTCNGCNGCNATGTCNTCNMGNTTYGTNCAR GGNGCNATGYTNGAYGAYAARAAYCARGAYTCNAARATGGARCCNGGNGGNGARGTNTCN GAYGARGTNAARGCNGCNGARATGMGNATGTTYGGNAARYTNACNMGNCARCARTTYGAR TGGCAYCCNGAYAARYTNATHTGYAARMGNTTYAAYGTNCCNAAYCCNTAYCCNGGNTCN GAYATHGTNGGNYTNCCNACNATHAARMGNGAYAARTTYTCNGTNTTYAAYTTYYTNAGY TTYGARAAYTAYCARCCNMGNGARACNGARGAYCARACNGARAARGAYCAYTCNAARAAR TCNGARGARGCNACNCARAARMGNGARYTNTCNGAYMGNTCNGGN------AARAARAAR GTNACNYTNTCNTCNATHTTYAARGTNYTNGAYGAYCCNGAYTTYCAYAARCCNATGGCN TCNAARCCNAAYAARTCNYTNATGGAR---CARAGYACNGARCAYGTNGARGGNCARGGN GARGARGAYCARGARGARAAR------GARGARACNGARACNGAYYTNGAYYTNTTYMGN GCNATHTTYMGNAAYTCNGAYTCNGARGCNTCNGAYGAY------MGNCARTCNGTNAAR GAYCCNGAYTCNATGAGYGAYGARGARGARGAYGAYMGNAARAARGAYGTNGAYGAY--- ------------------------------------AAYCAYTCNGTNATHCCNGTNAGY GAYTCNGTNYTNCCNGTNAAYGAYTCN------GTNATGCCNGTNAAYAAYTCNGTNATH CCNGCNAAY--------------------------------------------------- ------------------------------------------------GTNTCNGTNATH CAYGCNAAYGAYTCNAAYGCNGTNGCNGARAARGTNTCNGAYTCN--------------- ------------------------------------------GARTAYGGNCCNYTNYTN CCNCCNTCNGCNTCNATHTCNGGNACNGTNAAYACNGCNTCNGARGTNAARCCNYTNYTN ACNGARAARYTNATGTTYAARGARAARGARAARGAYMGNCAYAGYGARAARCAYMGNGTN AARAARGARAARAARAARAARTCNAARCAY---AARAGYMGNAARGARAARAARCAYAAR AARAARTCNTCNAARACNAARAARTCNAARMGNGAYAGYMGNGCNAGYGARGCNGAYTCN GARTCNAGYGAYGAYTCNGAYGTNTCNGAYACNAAYYTNYTNAAYMGNTTYATHCARGTN TCNAARYTNAARTCNGGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNGAYAARGTNGCNAARMGNGARCARYTNTTYAARACN ATGGTNGARTTYGAYTCNAARGCNAGYGAYCCNAARMGNTTYTTYAAYGAYMGNGGNGGN AARYTNYTNATHGARGARAARCARMGNAARAARATHYTNAARGAYYTNCCNAARATGGAR GARGARGTNTCNGARYTNATHGARCARTGGGARAARATGACNAAYAARGARTTYCAYGTN AAYGGNYTNMGNTTYCCNCARTAYGTNATHMGNCARATGGARGAYTTYCAYMGNCAYAAR GARCARGARAARCARGAYMGNATGAARGCNMGNCARAARCARACNCARGARGARGCNATG TTYGGNAGYAARTCNGCNYTNCCNACNCCNGGNAARMGNAARTTYGGNGTNCCNACNACN CCNATGMGNACNCCNYTNAARGCNMGNAARYTNAAYAGYCCNGTNAARACNCCNAAYACN ACNGGNMGNYTNCCNCCNAAYAGYMGNATHCARCAYAAYACNGTNTTYCARTCNYTN--- ---------GCNAARACNCCNYTNACNGCNTCNAAYAARAARMGNMGNTCNATHMGNYTN ATGCARAARGCNGCNACNGAYMGNMGNAGYTCNAAYTCNAARMGNMGNMGNTCNMGNGAY ATHTTYTCNCAYACNACNGTNAGYAGYGAYAAY--------------------------- ------------------------------------------------------------ ------TCNYTNAARATGGARMGNGCNGTNGAYACNYTNGARGGNATGTTYAAYAARGCN GARAARGAYYTNGAYCAYATGTCNMGNAARYTNGAYMGNCARYTNGAYAAYGTNAARGAY GCNGAYCCNAARACNAAYCCNGTNAARYTNATGAARAARYTNGARYTNATHAARAARGAR TAYGCNAAYGTNGTNCARGAYGTNTAYGCNATHCARGARGCNCARAARGARTTYTCNGAY ATGTTYMGNTCNCARYTNYTNACNYTNACNGAYGCNYTNCARAARYTNGARATGAAYACN GGNCARTCNTCNGARAAYAAYGARAARGARMGNGARGTNTTYGGNTCNYTNTCNAGYYTN YTNGGNATHCCNCCNGGNCARYTN---------------------------GARTGYCAR GCNAGYGGNAAYGAYATHAAYGARATHAAYGCNGTNTCNCCNTCNGARTCNTCNTCNTCN AAYTCNGTNACNAAYGGNGCNACNGCNAARGARGARAARAGYCARGAYTCNGCNAGYGTN TCNAARMGNAARAAYTCNGARGARTTYTGYGARATHTCNGARGARGARTTYCARTCNGTN TCNAARYTNATHAARCARMGNTGYAARMGNGARGAYGTNAAYAARGTNTAYMGNCARYTN TGGCARCAYTTYAARGARGARAARAAYATHAAYAARYTNTCNCCNAARGAYATGAAYGCN ATGGGNYTNMGNGTNACNGGNGCNACNGGNGARGCNAARYTNAARGTNYTNMGNGCNYTN AARYTNTGYGAYATHGAYMGNAARGGNGAYGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AAYATHACNYTNMGNCARACNGTNGCNACNMGNMGNTAYAGYGAYCAYTGY GARAAYCCNYTNAAYAGYGARTAYMGNCAYAGYYTNMGNGGNAARTGYGGNGARATGTAY GCNTCNGARACNAAYACNGCNTCNACNTGYGAYGAY------------------------ ------------------------------------------------------------ ------------------------MGNGAYGGNGTNGARGAYAARCAYGGNMGNTCNTTY TTYGAYGTNCCNTGYGTNGAYYTNGCNTAYAAYYTNYTNGGNCARTTYATHGTNMGNACN ATHGGNGGNCARMGNATHMGNGGNMGNATHGTNGARACNGARGCNTAYYTNGGNCCNGTN GAYAARGCNGCNCAYAGYTAYCARGGNAARMGNACNCCNAARAAYGARTCNATGTTYATG GTNCCNGGNACNAGYTAYGTNTAYAAYATHTAYGGNATGTAYTGYTGYATHAAYATHTCN AGYCARGGNGAYGGNGCNGCNGTNYTNATHMGNGCNYTNGARCCNATHGAYGGNAARGAY YTNATG---------CARCARGGNMGNAAYGCNAAR------ACNMGNAARYTNYTNAAR GARAARGAYYTNACNAAYGGNCCNTCNAARYTNTGYCARGCNYTNCAYATHAARAARAAY GAYTTYGAYAARGTNGAYYTNACNACNTCNGAYGTNATHTGGYTNGARAARGGNGAYGGN GTNGAYAGYCARGCNGTNGTNAGYTGYCCNMGNATHAAYATHGGNTAYGCNGGNGAYTGG AARGAYAARCCNYTNMGNTTYTAYGTNYTNGGNAAYTCNTGYGTNAGYGTNMGNGAYAAR AAYGCNGAR------------------MGNAAYGTNGTNTGYTAYTAYTCNAAYTGGCCN CARTAYMGNCCNGGNATGGGNMGNTAYACNGTNAARGAYATHGAYGCNTCNYTNTGYACN CAYATHATHTTYGCNTTYGCN---AARGTNGTNGGNAAYAARYTNGARCCNTAYGARAAY AAYGAYGGNGGNATG------------------TGGACNGCNYTNAAYAAYYTNAARAAR ACNCAYCCNCAYYTNAARACNYTNYTNGCNGTNGGNGGNTAYAAYCAYGGNCCNCARCCN TTYACNGCNATGAGYACNACNCARCARAGYMGNMGNGARTTYATHATGAAYAGYATHGCN YTNATGMGNAARTAYGAYTTYGAYGGNGTNGAYYTNGAYTGGGARTAYCCNGGNCARATH GTNGCN------GCNGAYAARCARAAYYTNGTNCAYYTNYTNAARGARATGMGNATGGAR TTYGARAAYGARGCNMGNCARCAYAAYMGNAAYMGNYTNYTNATHACNATGGCNGTNGCN GCNGGNATHMGNAAYGCNGARAARGCNTAYGAYYTNCCNACNATGGAYMGNTAYATGGAY ATGTAYAAYYTNATGGCNTAYGAYYTNCAYGGNTCNTGGGARAAYCAYACNGGNYTNGCN TCNACNYTN---------------------CARTCNAAYGTNGAYAAYYTNTCNGTNATH GCNGCNGTNAAYTGGTAYYTNMGNAARGGNGTNCCNYTNCAYAARATHAAYYTNGGNYTN AGYTTYTAYGCNMGNACNTGGACNYTNAARACNTCNGGNGAYATHMGNYTNGGNGCNCCN ACNACNGGNCCNGGNMGNAARGGNCCNTTYACNMGNGARCCNGGNGCNYTNTCNCAYTAY GARGTNTGYCARYTNAARGARAARGAYGCNACNGGNCARACNATG--------------- ---TAYGGNGGNTAYGGNGAYCARTTYATHACNTAYGARAAYGARGAYGCNATHAARGTN AARYTNGAYTAYATHCARAARATHGGNYTNGGNGGNGCNATGGTNTGGGCNYTNGAYCAY GAYGAYTTYAAYGGNCAYTTYTGYCAYAARGGNAARTAYCCNYTNYTNTCNYTNGTNTAY TCNAGYATGMGNCCNGTNATHAAYCARACNCARCCNATHGAYGTNTAYTTYACNTTYCAY YTNYTNAGYYTNYTNGARATHGAYGARGTNCARCARMGNATGCAYATHAAYGCNTGGGTN AAYTTYTCNTGGTGGGAYGARGTNMGNACNTGGAAYCCNCARGAYTAYAAYGGNATHGAY GTNYTNCAYCCNGAYCCNYTNGAYATHTGGMGNCCNMGNACNATHGTNGCNAAYTCNATH GGNCCNMGNGAYATHTTYGGNGAYGARTAYGCNCCNTTYTCNATHYTNTCNACNGGNTCN ACNACNTGGTCNCCNGGNGCNATHTTYTAYYTNTCNTGYCARYTNGAYYTNACNTAYTTY CCNTTYGAYACNCARACNTGYGCNGCNMGNATHYTNACNAAYGAYYTNGCNACNGARATH AAYGTNATHCCNACNAGYCCNTTYGTNYTNGCNMGNGGNTAYACNCCNCAYGGNGARTGG GAYYTNGARTCNTCNTCNGTNACNAARTCNATHATHGTNTTYGGNGGNMGNTCNTAYTAY GTNMGNACNATHTCNYTNGTNTAYAARMGNMGNCCNACNTAYTAYYTNYTNAAYGTNYTN AGYCCNGTNATGGTNYTNTCNTTYYTNTCNYTNYTNGGNTTYATHGTNCCNAARGARAGY GGNGARMGNGTNTCNTTYGCNATHACNGTNYTNYTNTCNYTNGCNGTNTTYATGGGNGTN ATHTCNGGNCARYTNCCNCCNAGYTCNGAYACNATHCCNGTNATHAGYATHTAYATHTTY AGYYTNYTNTGYYTNAGYGGNTTYTCNGTNTTYATHATHGTNTCNCARYTNMGNGTNYTN TCNCAYATGGCN------------------------------------------------ ------------------------------------------------ATGTAYACNTCN TCNGAYCAYATGGAYATGTCNCCNCARCARTCNTCNTCNCCNTCNCCNMGNAGYACNAGY GAYGGNMGNCARYTNCCNAGYATHCCNAGYMGNCAYCCNCAYTCNCARACNGTNAGYTCN TCNATHAARGGNAAYAAYCARTCNAAYAGYGTNAARGGNAGYAAYGGNTAYGGNCCNTTY TTYCARGARTAYTCNYTNATGGCNGARTTYAAYCARGTNCAYCAYCARAAYATHCCNGGN YTNTAYGCNATGCCNTCNTCNAARTCNCCNYTNYTNTGGTCNGGNYTNATHTTYATHMGN CARGGNYTNTAYCARGGNGCNGCNYTNMGNTTYACNYTNACNATHCCNCAYAAYTAYCCN GAYGGNAAYTGYCCNACNYTNGTNTTYGARTAYCCNGTNTTYCAYCCNYTNGTNGAYCCN GAYTCNGGNGARYTNGAYGTNAARMGNGCNTTYCCNMGNTGGMGNMGNAAYGTNAAYCAY YTNTGGCARGTNYTNYTNTTYGCNAARAARGTNTTYTAYAAYATHGAYACNAARATGCCN TCNAAYCCNGARGCNGCNGTNYTNTAYGARCARGARCCNGARYTNTTYAARAGYAARGTN TCNGARTCNYTNGARGCNGCNMGNGARMGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AARCCNTGGGCN AAYATHGGNTTYCCNACNATHGAYCARYTNGTNAARGAYGGNATHAAYCAYTAYGCNTAY MGNATHTGYGGNCCNGCNMGNYTNTCNGGNMGNYTNGCNCCNCAYGTNYTNGTNAARAAY GTNGCNGTNTAYMGN------CCNCARCAYACNCCNTAYGGNMGNGGNTTYAAYYTNTAY TAYATHCARGCNACNGARCAYCCNYTNTTYYTNATGGCNATGACNAARTAYATGGAYGAY ACNATHAARAAYYTNACNACNGCNYTNAARGARAARGGNATGTGGGARAAYACNYTNGTN GTNTTYACNACNGAYAAYGGNGGNCCNATHTAYGARCCNGGNAAYAAYTAYCCNYTNMGN GGNGGNAARTAYTCNGAYTTYGARGGNGGNGTNMGNACNACNACNTTYATGTCNGGNGGN TAYATHCCNMGNMGNGGNAARGTNCAYCARGGNGTNGTNTCNYTNGCNGAYTGGTAYACN ATGTTYTCNGARYTNGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GGNATHTGYGARCARTGGAARGGNTGY------------------GGNATHMGNGARACN TCNACNATHACNTCNGTNGAYAARGAYTCNTAYATHCARGTNACNATHGGNAAYCAYAAR AAYTAYTTYGCNYTNTAYATGAAYAAYGARYTNAAYAGYGARGTNGARGAYACNGAYATH AARATHCCNATHYTNGAYATHACNCCNAGYGGNGAYGTNGTNTAYGARCCNGGNCARAAY AGYACNATHACNATHGTNAARAGYAARGAYGAYGARCCNGGNGARAAYTTYCAYTCN--- TCNTTYATHATHGCNAARCCNGGNGAYAAYGARYTNMGNTCNGAYTTYGAYGAYGAYGAR AAYGARAAYATHTTYCAYCCNGARAAYGARACNAARTAYYTNGAYAARAGYGARMGNACN ATHAARATHGARACNGAYAAYTCNCCNTAYTCNGGNATHYTNCARTTYTAYTCNMGNATH TAYTTYAARCAYGGNYTNGTNYTNGGNGTNGARAAYCAYAARMGNGTNATHYTNMGNCCN TCNACNCARAARACNGTNTTYCCNMGNGGNMGNATHTAYGARMGNAAYTTYMGNTTYCAR GARAARATHGARAAYGGNGAYCCNATHATHTTYTGYAGYTAYGGNGARAARTGYACNAAR TCNTGYACNTTYTAYGGNAAYGAYYTNAARGARYTNGARYTNTTYAARACNGTNAAYGGN AARACNACNMGN------GARCARATHACNACNTAYGAYCCNAGYTAYGTNGCNTAYGAR MGNGARATHACNCCNGCNYTNGGNGAYGCNTCNCCNGTNACNTAYACNTGYMGNGTNATH AAYGTNGARGGNCARAGYYTNAAYTTYAGYTAYGTNYTNAAYTTYGGNCARGARGTNAAR ATHYTNMGNAAYGARACNMGNATGCARAARYTNGAYAAYGGNYTNGTNCARGTNGTNTGY ACNGCNAGYGGNTCNCCNYTNCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CAYCAYMGNYTNTCNGGNCARAGYTAYGARTCNGGNGTN TCNTCNMGNCARAGYTAYCAYTCNACNTCNTCNTCNTCNCAYGGNAGYYTNGAYMGNYTN GARGAYCCNGGNATHCCNTCNACNATHAAYGTNACNCARYTNTTYCARGCNGGNGTNCCN GAYACNGARGTNYTNCAYGCNTGGYTNAAYGAYYTNGGNTTYGARGARGTNTAYCCNYTN TTYYTNCARGCNGGNTAYGAYATGCCNACNATHTCNMGNATGACNCCNGARGAYYTNACN GCNATHGGNATHACNAARCCNGCNCAYMGNAARMGNYTNAARGCNGARATHGCNMGNYTN CAYATHCAYGAYGGNATHCCNGAYTAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNYTNGGNCARGTNCCNTCNAARAARAAYTAYGARTGYGTNTGYCCNAAYTGY CARMGNCAYYTNGCNGCNTCNMGNTTYGCNCCNCAYYTNGARAARTGYATGGGNATGGGN MGNAAYTCNTCNMGNATHGCNAGYMGNMGNATHGCNAAYAAYCARAARCAYGGNAGYGAY GAYAGYGGNCARGAYGAYGARAAYGAYAAYGAYTGGAAYTAYGCNCCNGARTCNAARMGN YTNMGNAARYTNAARAARGAYAARATGTCNAAYTCNCCNMGNAAYMGNMGNYTNGCNAAR YTNMGNAAYAAYAAYTTYMGNAARYTNMGNAAYGGNGGNGAYCAYCAYACNACNACNGCN GCNACNACNGCNACNCCNGCNTCNGCNGCNGTNACNACNGCNGGNACNACNATHCCNACN ACNGCNGAYYTNGGNGGNATGGAYTAYACNGAYATHCARGARCAYGTNCCNAAYTAYGAR ACNATGACNYTNGARGARMGNAARGCNYTNYTNYTNACNAARTGYGGNGTNATHTCNGAR ATHACNAARAARATGTGYACNMGNTCNACNAARTGYGCNCARCAYACNGAYGARCARMGN MGNCARGTNMGNCAYTAYYTNYTNMGNCAYAAYMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARTTYATHTGYAARTGYTTY TAYTCNAARAAYATHTTYYTNCCNAARTAYAARYTNCAYYTNACNTAYCARAAYGAYGAR CARTTYTGYCARGARTTYMGNCARGAYYTNMGNATGMGNGGNTGYGCNTCNACNGAYCAR TAYCARGCNGTNYTNACNGARATHAARAARGARATHTCNMGNMGNAARAAYTTYCAYCAY GARGCNTAYAARMGNCAYAARATHATHTCNGARTCNTAYATGMGNYTNCAYCCNGTNYTN TGGGARTTYCARCCNTCNTTYATHGAYGAYMGNYTNTCNACNATHGTNGAYTCNATHTTY CARATHYTNAARAARGARGARGCNGARAAYATHATHYTNCAYAAYGGNGGNAGYATHGTN GGNCCNTAYYTNTAYAARATHCCNGTNTTYTCNATHGCNTTYTGYAARCARYTNGTNGAR GARYTNTCNCAYTTYGARGARAGYCCNTGYCCNAARGGNMGNCCNAAYACNATGTCNAAY TAYGGNATHTCNYTNGAYGARATGGGNYTNTCNGARAARYTNATHACNYTNATHATHACN CARTAYATHCARCCNYTNACNACNGCNYTNTTYGGNCAYTGGTGYCCNGARAARYTNGAY TCNTTYMGNTCNTTYTCNGTNYTNTAYGGNCCNGGNAARGAYACNGARYTNAGYATGCAY TTYGAYAAYGCNGARGTNACNYTNAAYGTNTGYYTNACNTCNGARTTYGARGGNGGNCAY YTNGARTTYMGNGGNYTNTGGGGNGAYCCNGARTCNGARAAYTAYAARGAR--------- ---ACNGTNATGCAYCARATHGGNTTYGGNGTNYTNCAYYTNGGNCARCAYACNCAYMGN GCNYTNCCNATHGARTCNGGNACNMGNTGYAAYYTNATHYTNTGGATGMGNAGYTCNGCN GTNMGNAAYCARTTYTGYMGNATGTGYGGNTCNAARCCNGAYATHGTNGARGTNCCNTTY GCNGGNGAYGGNTTYACN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AAYCAYMGNAGYGGNATHGTNATGTGGCCNGGNGCNMGNTAY TCNATHAARTGGGCNMGNCCNACNATHCAYATGCCNTAYGAYTCNGGNGTNAGYGARATH GARMGNGCNGAYGCNGTNYTNGGNTGGTTYACNCARGAYAAYCCNATHAAYYTNGGNATG ATHTAYTTYGAYGAYCCNGAYYTNATHGCNCAYAARAAYGGNCCNGAYTCNGARAARGTN ACNGARTAYATHAARAARGCNGAYGAYATHGTNGGNCAYATHYTNTCNGTNYTNAARCAR AARAAYYTNYTNGAYGAYATGAAYATHATHATHACNAGYGAYCAYGGNATGACNTCNATH TCNMGNAGYCARYTNATHTAYTTYGAYGAYATHATHCCNCAYGAYTGGGTNGCNATGACN ACNATHAGYCCNGCNYTNTCNATHTTYCCNAARCARGGNATGGARGARMGNATHTAYAGY AARYTNAARGARGCNTCNCCNGAYAGYCAYTTYGTNGTNTGGAARAARAARGAYATHCCN GARMGNTTYCAYTAYAARCAYAAYATHMGNGTNGCNCCNATHATGGCNYTNGCNGAYYTN CAYTAYTCNTTYYTNGTNAAYAARCCNATHGARMGNTTYACNTCNGCNGGNAAYCAYGGN TAYGAYAAYGARTTYCARGARATGCAYCCNATHTTYYTNGCNATGGGNCCNTCNTTYAAR AARGAYTAYTCNGTNAARACNTTYGAYAAYGTNGAYGTNTAYCCNYTNATGTGYCAYYTN YTNGAYYTNGAYCCNGCNCCNAAYAAYGGNAGYATGTTYATHGTNTCNCARGGNYTNTCN AGYCAYGARACNACNAAYTGGACNTTYGCNACNTAYATHTTYYTNYTNATHTTYATHGGN AGYATHGGNGGNATHTTYATHGTNGCNACNTGYMGNCARCAYMGNTAYYTNAARMGNAAR ATGTTYCARAAYMGN---------------MGNTCNTAYTCNATHGARAARACNTGGGAY GGNCARTGYYTNTGYCAYGAYCCNGTNMGNATHTCNYTNGGNGARAGYCARCAYGGNGAY ATHYTNYTNAARGTNGAYGCNCCNTTYTTYAAYAGYCCNGCNAARCCNATHGGNCCNGCN GGNCARCCNTTYCCNCARYTNTGGGAYTAYGARGTNGTNGARGCNTTYTTYYTNAAYGAY AARGAYCARTAYYTNGARATHGARYTNAGYCCNCAYGGNCARCAYYTNYTNYTNYTNYTN AAYGGNMGNMGNAARATGATHAARGAYAARYTNATHYTNAAYTTYACNGCNACNATHAAR GGNGAYAAYTGGACNGGNGARGCNACNATHCCNMGNGAYTAYYTNCCNTCNCAYGTNACN AARTTYAAYGCNTAYGCNATHCAYGGNGARGGNGAYGCNMGNCARTAYGARGCNYTNTAY CCNGTN---------ACNGARAARGTNAARGGNATGCARCCNGAYTTYCAYMGNYTNGAR YTNTTYCARCCNYTNGAYATGAGYACNATHYTNAGYAAYTAYAAYCCNTCNCARGTNTCN CCNYTNTGG--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AAYGCNGAYGARGAYGAYGAYGGNTAYCCNAGYGAYGGNATHGTNCARGTN GARGARGARGARGARGARAAYGAYACNGAYAAYGGNACNTAYACNATHGARGCNGAYGCN MGNCARMGNAARAAYYTNMGNAARCCNGGNCAYATGGGNATHGGNGCNMGNCCNAARACN TCNMGNGGNMGNCARACNTTYCCNCARCCNGCNTAYACNGAYCARACNACNAARAARGGN GCNAARAARACNAARMGNAAYYTNCARGCNAGYGARMGNGARTCNAARATHMGNCARGAR AAYTAYMGNTCNGCNGARGAYYTNATHCAYGARGARGARGTNAARGGNAARAGYGCNGAR TGGTTYMGNYTNATGGARAAYMGNATGAAYAAYYTNAGYTCNTCNGTNGARTCNYTNGTN AARAARYTNGAYTCNGGNGGNMGNCARYTNAGYGTNTCNYTNAGYCARGARAAYACNTCN CCNCCNATGCARGARCARATGYTNCARYTNCARAAYCARTCNATGATGYTNAGYTTYAGY CAYATHGTNCARTCNYTNGCNMGNCARCARGGNGAYATGCARCARYTNCAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TCNCCNTCNGCNTCN CCNCCNMGNAGYCCNTCNTTYAARGTNGAYTTYCARGTNTCNGAYCARGAYYTNGCNYTN ACNTCNATHCCNGGN--------------------------------------------- ------------------------------------GTNAGYTTYGAYCCNMGNAARMGN AAYTTYTCNGARGARGARYTNAARCCNCARCCNATHATHAARAARTCNAARAAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AAYMGNCARGCNTAYATGGAYGCNGTNYTNCARGAYCAYCARCARACNATGTCNGTNATH CCNYTNAGYMGNCARCAYAGYTCNAAY---TCNYTNGARAAYGTNGAYACNMGNTTYATH ACNCAYAAYAARGTNATHCARMGNATGGGNATHAGYCARAAYMGNAAYMGNMGNGCNCAR TCNGCNAARGTNMGNACNMGNTCNGCNAARAARGAYGARGTNAARGCNATGGAYATHTCN YTNAARGAYYTNGTNGGNGAYATGCCNTCNAGYAGYCAYTTYGTNACNYTNGGNGAR--- ------CARMGNACNATGACNCCNTTYCARATHAAYMGNMGNMGNCCNCARACNTCNCAY ---CCNMGNCAYCCNCCNAAYACNTAYAAYGAYCCNAGYMGNTAYTCNAARGGNGAYGTN TTYGAYGTNMGNGARGCNGAYGGNGTNAARAARCCNMGNCCNGTNAGYGCNTCNAGYYTN MGNGAYTCNGAYGCNGCNMGNTCNMGNCCNMGNTCNGGNAARMGNGARAARGGNGGN--- TCNCARCARGCNTTYATHACNCARAARAAYGARMGNTCNYTNMGNTAYGARGCNACNAAR CCNGTNTAYGTNTTYCCNAARCARACNCCNACNAARCCNMGNMGNAAYTCNGAYGAYMGN GTNTCNCARYTNACNMGNTCNAAYAGYCAYACNGGNYTNATGTCNCARACNGAYGTNATH AGYGCNTCNAGYGCNGCNAARGTNCAYCCNATHCAYGAYAAYCAYATHGTNCARTCNCCN ------------TCNCARCARAAYCAYGGNGARGGNTAYTTYACNGGNGGNGAYCAYTAY GCNAAYATHGARAAYGAYTTYGARAAYYTNGARGCNGAY---TCNGTNYTNCARAGYAAR CCNCCNATGTCNATHMGNGTNAARTCNGCNCAYACNMGNMGNCCNGCNCAYATHGAYAAR TTYGCNGAYGARGARMGNGCNYTNMGNGARATGGARGTNGAYTTYAARAARACNGCNYTN ACNYTNCARAARAARYTNGGNATHGTNGARACNGGNATHATHACNYTNGAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TAYGGNAARTCNTAYTGYAARCARATGAARYTNCAYCCNGAYGCN TAYTGYCARYTNGCNATHCAYYTNGCNTAYTAYACNATGCAYGGNMGNATGGCNCCNGCN TAYGARACNGCNCCNATHAARCARTTYTAYCAYGGNMGNACNGARACNYTNMGNTCNTGY ACNATGGARGCNAARGARTGGTGYCARAGYATGGGNGAYAARTCNTGYTCNAAYACNMGN MGNTAYGAYYTNTTYGTNAARGCNGTNACNAARCAYAAYGCNAARATGGCNGAYGCNTCN GAYYTNAARGCNTGYGAYMGNCAYYTNATGGGNYTNTAYYTNATHGCNAARGARGARAAY ATGCCNGTNCCNATGYTNTTYCARGAYCCNTCNTTYGTNAARAGYGGNGGNGGNGGNAAY TTYYTNYTNTCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNACNATHAARGAYGCNACNTGYTCNGAYTCNGGNYTNTAY TTYTGYTCNGTNTCNTAYYTNGCNGAYGGNTCNCARCCNGTNCCNGTNAARAARCAYGAR GARYTNAAYGGNACNATGGTNGCNTCNCARATGMGNATHCARATHGARCCNGAYGARGCN AARTAYAGYGTNAAYGAYACNATHMGNATGACNTGYAAYGTNGARGCNCCNGARGAYTAY AAYTTYTAYTGGAARMGNMGNTGYCCNAAYMGNAAYACNAAYACNCCNMGNTTYGTNMGN TAYCCNGTNCARAAYGAYATHAARGARCAYAARAARGARGCNGTNCCNAAYAAYCARTGY GGNGTNTAYAARCAYAGYCARACNYTNGARTTYCARATGAGYGAYGARATGGARGAYTGY ATGYTNMGNTGYGARTTYGGNGARMGNGAYGGNAAYYTNGAYAAYATGATGGCNAAYTTY ACNTTYYTNYTNMGNACNCCNGGNGGNAAYCCNGGNGGNTCNAARTCNTCNAGYGCNTCN AGYGAYGAYYTNGTNATHGGNYTNACNGTNTCNYTN---------YTNYTNYTNGCNATH ATHGCNGCN---GCNGTNYTNATHTAYGTNTGYTGGTGGMGNAARMGNACNCCNAGYCAR GAYAARTAYAARGAYGAYCCNGAYGCNGGNCAYAAYGTNAAYAGYGAY---CAYGCNCCN CCNCCNGTNTTYTAYTCNAARCCNCAYAARCCNCCNAARAAYGAYATHAAYGGNGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------YTNATHYTNACNTGYGGNGGNACNATHGAYAARCARTAYCCN CARGGNCCNGGNGCNTAYGCNTTYGARTTYGGNGARGCNGCNGTNGGNAARGTNYTNAGY MGNYTNTGYCCNTCNTTYCCNTAYCARATHGARAGYATHTGYGCNAARGAYGGNCARGAR ATGYTNGAYGGNGAYMGNGARGAYATHYTNMGNGCNGTNATGGAYGGNAGYCARCARYTN GTNYTNATHACNCAYGGNACNGAYACNYTNTGYGAYACNGCNMGNTAYYTNGTNAAYGCN GGNGTNGGNCARGGNYTNCARTAYGGNCCNGGNGTNGGNGGNAARACNGTNGTNYTNACN GGNTCNTTYAARCCNGARGCNATGAARGAYTCNGAYGCNGARTTYAAYGTNGGNTTYGCN YTNGGNTTYYTNYTNGCNYTNACN---CCNGGNGTNTTYATHGCNATHGARGGNGGNATH YTNGAYGGNAARTAYGTNATGMGNMGNGARGAYGGNAARTTYYTNGAYGARMGNTTYGCN YTNAARCARTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATHTTYYTN TTYGGNYTNTAYGARAGYGTNACNGAYAAYACNACNTCNAAYGGNACNACNYTNACNGAY ACNYTNAARGAYGTNYTNGGNGAYGTNAARAARGCNTTYGAYAAYGAYGTNACNCCNTTY TTYGCNYTNTTYATHTGYGCNTGGGGNACNGTNTTYYTNGARGTNTGGAARMGNCARTGY GCNACNYTNGCNTAYGARTGGGAYGTNGAYCARTTYGARGCNAAYGARCCNGAYMGNCCN CARTTYTAYGGNACNAGYGTNAARCCNGAYCCNGTNACNTCNTGYTCNATHATHATHTTY ATGTGYYTNYTNGTNGTNGCNAGYYTNGTNGCNGTNATHGCNTAYMGNGTNATHATGAAY GTNGAYTAYTGYCCNAAYATGCCNGAYAAYGARTGYTTYYTNGTNACNACNYTNGCNTCN TCNATHYTNAAYGCNATHTCNATHYTNATHTTYGGNAARATHTAYGAYAARATGGCNGTN GTNYTNACNGAYTGGGARAAYCAYMGNACNCARACNAARTAYGAYGAYGCNYTNATHATH AARYTNTTYGCNTTYCARTTYGTNAAYAGYTAYGCNTCNTGYTTYTAYATHGCNTTYTTY MGNGGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNGTNAARTAYGGNGARYTNTGYAARAAYATGAARTCNAAYATHMGNGGNAAY YTNACNGCNTGGGARMGNGARAARAARCARATHMGNCARYTNGARAARGTNCARGTNAAR CARCCNGCNAAYAGYCCNCARGTNATHAARGCNCARAGYGAYYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNGTNGAYMGNGCNAARGAR GAYATHAARMGNGTNATHAAYGCNATHGAYAARGTNMGNAARTGGGARAARAARTGGGTN ACNYTNGGNGAYACNTCNGTNACNATHYTNAARTGGGTNCCNGTNACNGCNCARGARAAY CCNGGNGCNYTNMGNAARATHCCNGGNGTNAARACNAARACNTAYTCNAARGCNMGNGTN GARMGNGARMGNGARYTNTAYAAYGCNGARACNAAYGGNYTNCCNMGNGCNAAYTCNCCN GCNGAYTCNACNAGYAAYAAYACNAAYATGTCNAAYACNAGYTCNCCNTCNTCNAARACN CAY------AAYACNGARAARCCNAARAAYGGNACNGTNACNAAYAGYCARAAYTCNGTN GTNTAYTCNGARGARAAYACNCARCARTCNATHGGNTCNTTYGGNTCNGARAAYYTNAAY GARGAYTCNAAYATGTCNTTYCCNGARAAYAGYGGNATGAGYGARCARGGNGAYCAYAAY GARTTYTCNCAYGAYAGYAAYGAYGCNGAYCCNGGNATGMGNGTNGCNATGAGYATGGTN GGNGAYGARGARCARGARGGNGGNAAYAARGAYGAYCCNAARACNGAYCARTCNCARCCN GAY---GARCCNGCN------TCNCCNGAR------------------------------ ATGTCNGARAARCAYGAYTTYGGNATHGCNCCNGTNACNTGYCAYGCNTTYAGYAARGAY MGNAAYGGNYTNGCNATGTCNYTNAAYGAYTCNAAYGTNAARATHTAYAARAARTCNGGN AGYAARTGGGAYGARACNGAYACNYTNAGYGARCAYGGNCARMGNGTNACNAGYATHGAY TGGGCNCCNAAYAGYAAYMGNATHGTNACNTGYTCNGCNGAYMGNAAYGCNTTYGTNTGG ATGCCNGARGAYGGNAARTGGAARCARGTNYTNGTNATHCCNMGNATHAAYMGNGCNGCN ACNTGYGTNAARTGGTCNCCNAARGARAAYAARTTYGCNGTNGGNAGYGGNTCNMGNYTN ATHGCNATHTGYTAYTAYGAYGAYGARAAYAAYTGGTGGGTNAGYMGNCAYATHAARAAR CCNATHMGNTCNACNGTNACNTGYYTNGAYTGGCAYCCNAAYAAYGTNYTNYTNGCNGCN GGNTCNACNGAYTTYAARTCNMGNGTNTTYTCNGCNTAYCARAARGARGTNGAYGARMGN CCNGGNGCNTGYAGYTGGGGNACNAARATGCCNTTYGGNGCNYTNATGGCNGARTTYAGY AAYGGNGGNGGNGGNTGGGTNCAYTCNGTNTCNTTYTCNCCNAGYGGNACNYTNGTNGCN TGGGTNGGNCAYGAYTCNAGYGTNTCNATHGTNGAYTCNTCNAARGGNAAYGARYTNGTN GTNATHAARGARAGYTTYYTNCCNTTYATGAGYATHTCNTGGGTNACNGARAAYTCNYTN GTNGCNGCNGGNTAYGAYTGYAAYCCNATGGTNTTYTCNGTNGAYGGNGGNMGNATHACN TGYCARGGNAARYTNGAYGTNCCNCARCARAARGARTCNGGNACNATGAGYGCNATGAAY MGNTTYAARAAYYTNGAYAARAARGCNACNGAYAGYGAYAGYTCNCCNGARATGAARACN CARCAYCARAAYACNATHACNCARGTNTCNATHCAYACNGGNGAYAARTCNAAYGCNAGY AARATHGCNACNAGYGGNGTNGAYGGNAAYYTNATHATHTGGGAYYTNAARYTNGAYAAY GCNAGYCAYAARCCNCARGGNGGNGAYAARAARATHGARACNAARAARYTNGAYTGGAAR GTNGARTCNAARATHGGNTCNYTNGAYAAYGCNAGYCAYGTNGCNGGNGGNGGNGAYAAR AARATHGARGTNGTNAARACNGARTGGAAYGCNAARTCNAARATHGGNTCNYTNGAYAAY GCNACNCAYMGNCCNGGNGGNGGNGAYAARAARATHGARACNCARAARACNGAYTGGAAY GCNAARTCNMGNATHGGNTCNYTNGARAARGCNAAYCAYAARCCNGGNGGNGGNGAYAAR AARATHGARACNGTNAARACNGARTGGAAYGCNGARTCNAARATHGGNTCNYTNAAYAAY GTNAARCAYAARCCNGGNGGNGGNGARAARACNTGYATHYTNTGYCCNTGYCCNGCNYTN ACNGCNTAYTGGACNAAYCCNCCNTCNTGYCCNMGNMGNGTNTGYTGYGARAGYAARTCN TCNTGYTGYTCNTAYYTNTGYTTYMGNGAYTCNAARACNGTNTCNGTNTTYGTNACNACN GTNTTYGTNACNTAYTTYATHYTNATGGAYATHGTNYTNTAYTGYTAYTTYATGAARGCN AGYYTNGTNGARGGNTCNAARGGNGGNGGNGCNGARGARATGTAYACNCCNTTYACNCAY YTNTCNGTNAARGCNYTNYTNAAYGAYCARCCNAGYCARTAYYTNATHGCNCCNAGYACN GARTGGYTNGARTAYTTYACNAAYTTYGCNAARACNTTYTAYTTYATHACNCCNAAYGTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNAARYTNATHGTNTTYGAYYTNGAYTAYACNYTNTGGCCN TTYTGGGTNGAYACNCAYGTNACNCCNCCNTTYAARAARGAYCCNGAYGGNAARGTNMGN GAYGCNMGNAARCAYCAYGTNACNTTYTAYCCNGAYGTNCCNCARATHYTNGCNAARYTN CAYMGNGARGGNTAYCARYTNGGNATHGCNTCNMGNACNGGNGCNATHMGNGAYGCNGAR GAYYTNATHMGNYTNTTYGAYTGGGAYAARTAYTTYCAYTTYMGNCARATHTAYCCNGAY TGYAARATHTCNCAYTTYAARGGNYTNCAYAARATGAGYGGNATHCCNTAYAARGAYATG YTNTTYTTYGAYGAYGARCAYMGNAAYATHAARGAYGTNTCNACNYTNGGNGTNACNTGY ATGTTYGTNCCNGAY---GGNGTNACNAAYGCNTCNTTYAARGARGGNYTNGARYTNTTY CARACNAAYMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GAYGTNMGNAARAARYTNGAYATGTCNGGNYTNAGYTCNMGNGAYTCNAGYTGGATGYTN GGNAAR---GCNAGYAARGGNTTYTCNGCNATHGAYGAYGCNAARMGNYTNYTNTCNTCN CARATGATHAARGCNTCNGARMGNACNTTYAAYCAYAGYATHGARTCNAARGAYAARTAY YTNCCNTAYMGNCCNCCNGGNTCNAARCARGTNTAYTAYATHGARAGYGAYACNGCNTCN GTNGCNGAYAGYGTNACNACNATGGARAGYACNCAYATHGGNTCNGAYGAYGCNAARGGN CCNGCNYTNCCNCCNCAYGCNTTYGGNTCNMGNAARGAYAAYCCNAGYACNTCNGGNATH TAYAGYTCNCAYGAYYTNTCNACNGTNMGNGARGAYGCNGARYTNGGNACNGTNGARGAR AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARACNAGYCCNGAYATG TGYAGYTTYYTNGARCAYTTYGARTGYYTNYTNGARAARGARAARATGATGGGNCARYTN AGYYTNYTNAAYATGGCNTGYGCNGCNAARGCNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGATHYTNTAY AARTGYYTNATHTCNGAYGAYGARATGTTYACNGAYGCNTAYCCNTGYGARGARAARGAY GGNTTYTAYATHYTNAARGGNAARYTNGTNACNAARAAR---GCNGAYGAYGTNGAYGAR TCNYTNATHGGNGGNAAYCCNAGYGCNGARGGNGAYGGNGAY---GARGTNGARGGNGAY ATGGTNACNGGNGTNAAYGTNATHYTNGAYATGMGNYTNCARTCNACNGGNTTYGGNTCN AARAARGAYTAYAARACNTAYATGAGYACNTAYATGAARACNGTNGTNAGYAARYTNAAR GARMGNGGNACNGCNGAYGAYGTNGAYGCNGCNAARCARGAYGCNATHAARGCNTTYAAY GCNGCNYTNGCNAAYTTYAARGARTGGGARTTYTAYATGGGNGARAGYAAYAAYCCNGAY GCNCAYGTNGCNYTNGTNGAYTGGAARGAYGARGARGARGAYGGNAARCARGTNTCNGTN CCNTAYGTNTAYTTYTAYAARGCNGGNYTNYTNGCNGARAARGGNGCNATGGGNTGYMGN AGYCARAAYGARYTNATHGAYATHATGACNGARGTNAARGARGGNAAYTTYACNATHGAY GAYGCNGTNMGNYTNTTYAAYTCNTGG--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNCCNMGNCAYGCNMGNGARTAYGAYGGNGCNGAYAGYTCNGAYYTNGAY GAYAARGAYCCNGAYGGNAAYGTNTCNGAYGARGAYACNGCNGAYGCNAGYGARACNGAR GARAARACNCCNAARTCNCAYAARCARAGYYTNCCNAAY---GGNAGYCARMGNATGGAR ATHAARGARCARATGTAYCARGAYAARYTNGCNCARATHAARAARCAYATHCARATGYTN GARGARGGNACNYTNCARGARTTYYTNAARMGNACNAARAARATHGARYTNAAYTAYMGN GARMGNYTNMGNGAYAAYGARATHTGYAARAARGTNGAYATHGARAARGCNGARCARAAY TAYYTNATHGAYTGYGAYAAYGCNCARAARGARTTYGARGARAARMGNGTNGCNATGAAR GARAGYYTNATHAAYCAYYTNAARGARAARAARGTNGAYYTNAARGARACNYTNATHTGY GAYYTNAARGARAARMGNGGNGTNATHGARYTNGARMGNCARACNGTNGAYYTNAAYGGN GCNGAYTTYATGGARGTNAARCCNACNATGACNMGNAARYTNMGNMGNMGNCCNAAYGAY CCNATGCCNATHCCNGARAARMGNMGNAARCCNTCNCCNGCNCARGTNAAYATHYTNYTN GAYGAYGAYGTNATHYTNGCNGAYYTNMGNYTNATHATGAARGTNAGYGGNAARCCNATH GCNAARAARCARGGNYTNGGNACNCAYAGYCCNATHATHGAYACNTCNTCNGAYGTNMGN ATHGARGAYGGNMGNYTNTGGTAYGAYAARAARTGGTTYCARMGNAAYACNATGGTNCAR ATHGAYAAYAARGARACNGGNTCNMGNATHCAYGGNACNATHACNAAYATHYTNAAYCAR GARATHTGGGTNAARAARAGYGGNGAYAAYTCNAARYTNMGNATHTGYYTNAAYCARTTY CARAARGGNAARTAYAAYATGAARAARMGNCCNACN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTCNMGNGCNGCNCCNTCNAARACN MGNGCNGCNGAYAARACNAARCCNCCNGCNTCNCARACNCCNGTNATHGCNCAYGARATH GTNCCNGGNAARTTYAAYGAYAAYGAYTGGAAYGTNATGYTNGARMGNGAYGGNGGNGAY GARTTYGTNATGGAYATHATGGAYGARYTNATGGARMGNACNATGACNACNATHTAYGAY AARTAYATHGARMGNCARYTNYTNCCNTTYACNATHACNCARGCNMGNGAYGCNATHATH GARATHATHGARTGGCARTTYYTNACNMGNGAYGARGGNGARGARAAYATHGARGCNGAY YTNGGNTGGACNCARGAYGARGARCCNGARCCNGCNGARACNGAYTGYTGGGCNCARGGN TCNGTNCCNMGNAAYGTNATHYTNGTNCCNACNCCN---------------------GAR YTNGARGARATHCCNGARGARGCNGARGTNYTNGARGARGARGCNGARAARGARCCNCAR GARGARATHTCNCARGARCCNGCNGARYTNGAYGAYGTNGTNTCNGARCCNGARGARACN TCNGAYATHGTNGCNCARCARGARAAR---GARGARAARGARATHGARAARGTNCCNTCN CCNCCNTCNYTNTCNGCNTCNACNAARAARAARTTYMGNCCNTAYMGNGGNAARYTNAAR TCNGCNGGNGTNAGYAARATGACNGARTCNYTNGARGAYACNGARATHAARATGATHTAY GAYGARATHGTNGCNTCNATGCCNCCNAGYGARGARAARCCNAGYACNYTNYTNAAYATG CCNGCNTCNTGYACNAGYATHYTNAARGTNCARACNGGNMGNCCNCCNGGNAAYAARGAY GTNGTNTAYGAYGAYYTNGGNAAYGTNGTNGCNGTNATGAARYTNGAYCCNGARAARYTN CCNACNCAYAARGTNAAYGTNAARTAYCAYGTNGTNGAYCCNGCNGTNGARGCNGCNCAR GCNMGNYTNGAYGCNATGMGNAARGGNAARTCNACNGGNAGYAARATGMGNAARYTNAAR TCNAAYAARAAYATHGCNGCNGARTCNACNTCNACNAGYTCNAARCCNAARGTNTCNACN TCNCAYGGNTCNGTNGCNCCNYTNCCNCCNCCNYTN------------------------ ---------------------------------ATHGARGARATGGARGTNTCNCAYGGN GTNATHGTNMGNGARGGNGGNMGNGTNAARAARGGNCCNGGNMGNTAYTAYMGNAARYTN GAYGTNYTNGARGARCAYCARAARGGNATGAARCCNGTNACNGTNMGNYTNAGYAAYACN GGNATHACNGTNAAYGAYYTNYTNGAYMGNAAYACNCCNATHYTNMGNCCNYTNGCNGAR CARTCNCCNYTNCCNCCNATHGTNCCNCARCCNCCNCCNCARCARCAR---CAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHAARTCNTGGATHACNTTYAAYGARCCNTGGTGYTCNACN GTNYTNGGNTAYGCNAAYGGNGARATGGCNCCNGGNAARAARGARCCNGAYACNGARCCN TAYATHGCNGCNCAYCAYATHATHYTNAGYCAYGCNMGNGCNGTNAARACNTAYMGNGAR AARTTYCARGCNAARCARGGNGGNCARATHGGNATHACNYTNAAYATGGAYTGGMGNCAY CCNYTNACNGARGCNGARGGNGAYAARGCNGCNGCNCARMGNGCNYTNGAYTGGCARYTN GGNTGGTTYGCNGAYCCNATHTGG------AARGGNGAYTAYCCNGARAGYATGMGN--- ------------------AARMGNTGYGGN---------GAYMGNYTNCCNTCNTTYACN GARGARGARAARCARYTNATHAARGGNACNTCNGARTTYTTYGGNYTNAAYCAYTAYTCN ACNGCNTAYGTN---GCNGCNCCNAARGGNAARGCNCARGGNGGNTAYTTYGAYGAYCAR GARGTNGARYTNATHGAYGAYCCNMGNTGGGGNMGNTCNGAYATGGAYTGG---GGNGTN GTNCCNTGGGGNYTNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGGMGNATH GCNAAYYTNATHATGACNACNTTYTTYTTYYTNGCNGCNATGGCNAAYACNAAYGAYAAY GAYTGGTAYATHTGGACNCCNATHTAYYTNTAYGCNTCNGTNYTNTGYYTNTTYGCNTTY ATHTAYTCNACNGCNGTNGGNAAYCARAGYTGGCARYTNYTNATGTCNGTNYTNYTNGGN GTNGCNATHGTNATGGGNYTNTAYCARYTNTCNYTNYTNTTYGGNGTNGCNCAYAARATG GGNAGYAAYCCNYTNAARYTNGARGARGGNMGNGARATGGGNGGNATHATHATHATHYTN GCNTGGGCNGGNATHTCNMGNTTYTCNCCNTTYGCNATGACNGGNCCNMGNTCNAARTCN AAYYTNATGACNGGNYTNYTNGTNGTNTCNYTNACNYTNGCNGTNGTNCCNYTNATHACN TGGTCNYTNTGYTTYGTNGGNGAYTGGCAYAARCAYYTNGGNCAYTGYTCNGGNATGTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------MGNACN------------------TAYAARTGYATHTTYTGY YTNAARCARTTYYTNTCNCCNTTYMGNMGNMGNAAYCAYGARAARACNCAYGCNAGYGAR GAYMGNAAYGARTGYCCNGTNTGYTTYMGNAARTTYGGNCAYMGNMGNCARYTNGARGAY CAYYTNAAYACNCAYACNGGNATHAARGTNTAYMGNTGYAGYATHTGYGAYGTNGAYTTY AAYAGYGARTAYYTNTAYATGATGCAYTAYAARGTNCAYTCNAAYGGNTGYAARTTYATH TGYACNATHTGYAAYAARGARTTYAGYTGYCCNGCNCAYYTNAAYAARCAYAAYAARAGY CAYYTNAARGARAGYYTNTCNYTNTGYTCNTAYTGYGGNAARGARTGYAAYGAYCCNAAR AARYTNYTNATHCAYMGNCARCAYCAYACNGGNGARMGNCCNTTYAARTGYACNYTNTGY GGNAARGCNTAYGCNAGYTAYGGNATGMGNTTYTCNCAYATGAARACNCAYACNGGNAAR MGNGARTTYGTNTGYCARACNTGYGGNAARYTNTTYAARGGNTAYTCNGTNYTNTAYACN CAYYTNMGNATHCAYACNGGNGARAARCCNTAYAARTGYCARATHTGYGGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATHGCNAAYATHGGNCARGAYGGNTCNTAYYTNGTNMGNAARAGYGARGAYGAY TCNGAYGTNATHGTNGTNTAYGCNGGN---GTNMGNAARTAYMGNGTNATGAAYCARGGN AAYGGNAARAARACNYTNTCNGCNACNGARCCNGARTTYGAYAAYATGGARGAYYTNYTN TAYCAYTAYTAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGGCNGAYTCNAARTCN AGYYTNGCNMGNGAYGGNACNATGCARGTNACNGCNAARGARGGNATHGAYTAYYTNAAR TCNGCNCAYAARGAYACNYTNYTNAARGCNCARGGNYTNATHAARGAYAARCCNGCNGTN CARMGNGAYGGNACNATGGTNTCNACNGCNAARGARGCNGARMGNYTNYTNGAYGGNAAY AARCCNGAYGCNGAYGCNCARACNMGNGGNCARCARAARCARATHGAYGAYATHAARAAY GCN---GARCCNCCNAARGCNAARAARGCNMGNYTNGCNAARGAYGGNACNATGGCNGTN ACNGCNAARGARGCNAARGCNYTNYTNGCNGGNGARAARYTNGGNGAYACNMGNCARGAR ACNAARACNAARACNGGN------AARACNCCNYTNMGNAARGCNAAYACNATGGCNMGN ACNGTNGARGARGCNAARAGYGTNYTNGAYGGNAAYGTNGAYYTNAGYGGNGGNMGNAAR ACNMGNTCNCARAGYMGNGGNGARACNCCNAARCCNTCNATHAARAARATGGGNACNATG CARCARACNGCNAARGAYGGNAARGCNTAYYTNAARMGNGCNAARGGNAARAARMGN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AGYACNCCNCCNGAYAGYCCNCAYAAYAGYCARCAYTTYCARYTNAAYGCNAAYAAYGAY GGNMGNATHMGNMGNAGYYTNCARCCNGGNCCNGGNYTNCARTAYMGNTCNCAYAAYTCN AGYGAYTCNAGYYTNGARMGNCAYAGYGTNGAYACNAAYGGNAGYGAYGARYTNAAYYTN GCNCCNGARGCNATGMGNGCNCCNTCNTCNMGNYTNCAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGCCNAGYYTNCCN YTNATH------------AARCAYACNATGGCNACNGCNGGNGCNAGYACNGCNMGNGCN YTN---------AARCARATGATHAARCCNCAYATHCCNATGATHAARTTYCCNAARMGN GARGCNCARCAYGARYTNCAR------GCNGGNGTNGTNGGNAAYCCNAAYTCNYTNGAY GCNYTNYTNACNAARAAYGTNACNYTNCARCARTCNGCNTCNGTNCCNCCNGCNTCNACN GCNAARGGNTCNTCNATHGAYTCNTCNGARYTNCCNCARMGNTAYMGNMGNAARCCNATH TCNAAYGARGARATHGARTTYATHGARAARGGNGGNCARGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TAYGCNCCNAAYYTNMGNGGNAGYGGNGTNCAYGGNGCNYTNATGGTNYTNGARCCNMGN TTYAAYTCNGARYTNTTYGCNGTNYTNYTNTCNATHCCNGCNAGYAARACNYTNYTNMGN MGNCAYYTNAAYTCNCAYTTYATHGGNYTNATHGGNGCNGARACNCARCARMGNAARMGN GARYTNGARGCNACNCCNGGNTTYGTNCCNYTNYTNCAYAAYAAYAARATHAARAARGGN AARTTYGGNYTNTTYAAYCAYAARMGNAGYMGNTCNGARCCNGARATGGAYAGYYTNATH TGYCCNCCNGAYYTNAAYGGNTAY---------------------TCNCCNYTNYTNTTY CAYGCNTCNGARAARYTNTGYGGNCARCCNATGAARAARMGNAARTCNATGGAYCCNCAR GTNGCNGCNGCNMGNACNCARAARAARYTNAARMGNATHGAYAARGARATHAARMGNYTN TCNMGNTTYAGYAARATHYTNAARCCNGTNGAYGARATHGARGGNGAYMGNMGNMGNYTN ATGGCNGCNGTNGARMGNAARMGNGARCCNACNGTNYTNACNTTYGARGARTCNGARTCN MGNGCNYTNYTNCARAARGCNTGGACNTGYTAYMGNACNAAYMGNCAYCAYGAYATGGTN CARGTNTTYTCNAARGTNTCNGCNGCNCARCARGARGCNYTNGARGARYTNMGNGCNGAR TCNGARGARYTNTAYCARGCNGCNATHCARAARGAYGARAGYYTNATHCCNYTNACNTTY GARGGNCCNAARGARACNCCNCCNATHAARTGYTAYGAYGCNCCNGAYGGNGAYTAYGTN GAYACNACNMGNAARTTY---------AGYGGNGAYGTNGARTGGAAYATHGAYATGGAR GTNAAYYTNTTYCAYGCNATGMGNGGNCAYAARCCNGCNGGNGTNAAYMGNCAYTTYCAR ATGATHGCNATHCAYGAYAARYTNAGYTCNTCNACNAARAARGTNACNTCNAGYGARGTN TGGAARCAYYTNTCNACNYTNTAYGAYYTNCARGCNYTNTAYGARTCNGARATHGTNCCN TTYCCNAAYAARAAYGGNGAYTTYTCNYTNATHGAYMGNGAYYTNYTNGAYYTNTGYACN AARTCNTTYCCNMGNTCNGCNTAYATHAAYAGYGCNCCNACNGARCAYYTNAARTCNGAR GCNTCNGGNAARAAYATHTCNAARTTYAGYACNAARCARGAYAGYAARGTNAGYTCNCAR ACNCCNAARGCNGARTCNAARAGYGARCAYAAR---TCNTCNAGYGCNTCNAARGCNGAY AGYMGNTCNAAYACNCCNTCNAGYMGNTCNGARTCNAARTCNGCNCAYCAYGGNAGYAGY AGYAGYGTNGGNGCNACNAGYTCNAARTCNTCNCAYCARAGYACNCCNACNTCNATHCCN TCNCCNTCNCCNAARMGNGCNAARMGNACNMGNAAYGTNAAYTCNGCNTCNGCNAGYCCN GCNACNCCNACNGARCCNCARTCNAARMGNMGNMGN------------------------ ------TAYATGGCNCCNGARATGAAYTCNACNTAYTCNTAYYTNGTNGAYGTNTGGGCN ATGGGNATHATHATGTAYTAYYTNYTNACNGARTAYCCNAARGAYAAYYTNYTNAAYGAR TCNATHAARACNGARGGNCCNCARTTYMGNGARCCNCARTGGGCNGCNGTNAGYGAYCAR GCNAARGAYYTNYTNMGNGARATHYTNACNCARGAYCCNGCNCAYMGNCCNTCNTCNGGN GARGTNYTNAAYCAYGARTGGTTYACNGGNAARAARMGNGARCAYCCNAAYGTNYTNAAR YTNATGAARGARTTYMGNCARGARCARGARGAR---GARMGNTCNGCNAARACNGAYGAY AAYATGAAYAGYGCNATHAAYGGNGTNGCNGARYTNCARGCNGGNGAYAGYTCNGTN--- ---------GARAGYTCNAGYGGNACNACNAAYGGNACNGGNAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GGNACNYTNTTYTTYTCNACNYTNATHTAYTTYGCNGARAAYGAY------GARAGYTTY TCNAGYATHCCNAARTGYTTYTGGTGGTCNGTNATHACNATGACNACNGTNGGNTAYGGN GAYATGTCNCCNAARTCNMGNTGGGGNTAYTTYGTNGGNACNATHACNGCNATHTCNGGN GTNYTNATGGTNGGNTTYACNGTNCCNGTNYTNGTNAAYAAYTTYATHATGTAYTAYAAY CAYACNGARTCNCAYATHCARMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYAARGTNACNACNGCNMGNAARMGNCARGARGAY MGNTAYMGNGARGARYTNMGNMGNGCNGARAARGARMGNAARGARTCNYTNGARGTNTCN ATGAAYAARYTNMGNGTNYTNGARGAYGAYCAYGARAARGTNAARAAYAARYTNGAYGCN TCNAARACNMGNAAYAARGTNYTNTCNAAYGARYTNAARGGNYTNAARGCNCARGTNCAR ACNYTNYTNMGNAARAGYCARAAYGAYGAYGARTTYATHGARGCNYTNATGAARCARCAR AARCARYTNAARGAYATGATGGARCARTCNTGYAGYAARCARAAYATGCARCAYCARCAR CARCARCARCARYTNYTNCARATGAAYATGAARAGYCARCARGAYAAYAAYATHGTNGGN CARYTNAARYTNATHGCNGCNCARAARGARTCNCARGTNAARATGYTNGARATGGARYTN TCNCARYTNMGNAAYCARCAYGCNCARATGTCNTCNGTNGAYTCNGARACNGTNACNTCN GGNTCNGCNATGACNGGNGCNATHACNCCNGGNYTNCCNGAYGAYGCNGTNGCNACNGTN AAYGGNATHACNTAYMGNMGN---------GARCCNAGYCARYTNTCNAGYGCNMGNTCN AGYGCNMGNTCNATGTCNMGNATGTCNAAYCARGCNCCNGGNGAYCCNMGNGCNCCNACN CCNACNACNAAYACNGCNAAYCARAARGARGTNGARAAYYTNMGNTAYCARATHCARGAR YTNACNGTNATGTCNAARGCNYTNGARGTNGARMGNGAYAARATGACNGARYTNAAYCAR GTNYTNCARTCNMGNYTNTCNGARGARGTNGAYMGNCAYAAYAARACNCARCARGARYTN CARGCNCARAARMGNTCNGGNATHGARYTNGARAARYTNYTNGGNMGNAARAAYATGGAR GCNATHAARAARGGNGGNGCNGAYGCNAARYTNAARTCNGAYMGNGGNGAYGAYTCNGAR GAYGARGARGGNGCNAAYTCNACNAARGCNGARYTNGTNACNMGNYTNGARATHCARAAR GAYGARATHCARTCNYTNAARYTNGCNYTNCARMGNAGYYTNAARGCNAARGARGARGAY YTNAARGTNTAYAGYAARACNYTNGAYGARACNAARCARGTNTTYYTNCARGCNYTNMGN CARATGAARGAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TAYGAYGTNGAYTTYTGYYTNCCNYTNGAYATHGAYAARGARCARGAYGAR TTYACNGTNAAYAGYGGNTGGATHGCNGGNGCNTTYTTYYTNGGNYTNYTNYTNGGNATH GGNYTNGTNYTNYTNYTNGCNMGNCCNTTYATHGCNTCNTGGGARAARAARAARCARCAR GAYGARGARTAYATGYTN------GGNAAYGCNCAYGCNGTNAARGCNGARCCNGCNGAY TCNGAYAARGAYGAYGCNGARAARAARGGNMGNMGNAARTCNAARGCNGGNAARGARAAR GARGGNGCNATHMGNGGNAARTCNMGNTTYTGGMGNMGNAARCCNAARGGNAARGARAAR GGNGARGARGTNAARGARGGNGAYGTNGAYCCNGCNTAYGCNMGNGGNATGGTNGAYGTN ATGYTNCARACNAAYAGYACNGGNGARGARGTNGARATGGCNGAYCARGAYATGGCNACN ATHATHTCNATGGARMGNGGNCARGARGARGARAARACNACNYTNATGYTNAARACNYTN GCNATHYTNYTNMGNAARMGNGTNGARAARMGNGARATHACNCARAAYTTYTAYACNGAY TTYYTNMGNAARACNGARGARGAYYTNAARGAYATGGGNACNATGATHGAYMGNGARAAR GARGARGCNGARGARAARYTNAARAAYGAYCCNAARYTNAGYAARGAYACNCARACNATG GARACNGARATGCARAARYTNCARACNGARTTYAAYCAYAARCARGCNAARYTNCARAAR GAYTTYMGNGAYAARATHMGNYTNGAYYTNYTNMGNTCNTCNGGNATGCCNGARTCNGAR GTNGARGARGTNATHTCNGGNYTNATGGGNAAYATGGCNMGNGTNGARGARAARYTNGGN YTNGARCARGCNMGNCARMGNMGNGCNYTNGARCARMGNYTNGCNAARMGNAARCARGCN ATGGARTTYCARCARGTNGARAARGARGARAARGTNAAYGARCARGARGCNAARGTNAAR GTNTTYMGNTCNYTNYTNGARAAYCAYACNAARGAYGGNTCNYTNYTNGARAARCARTGY GAYACNATHGTNTCNGAYTAYGARAAYGARYTNAAYYTNYTNAARAARTAYCAYGCNGAY GARTTYAAYCARYTNMGNYTNGARAARTTYGARATHYTNCARCARGAYMGNYTNAAYAAY TTYTTYAARYTNAAYAARAARCAYGARAARGARAARGCNGCNYTNYTNCAYACNGCNGAY AARAGYAAY---ACNGARGARTTYATHAARYTNTAYCAYGAYYTNATGACNMGNCARCAY ATGGARAARGARGCNYTNTCNGGNGARYTNGAYATGMGNGARATHCARGARATHCAYAAR YTNMGNGARGARTGYGARAARAARGARGCNAARGGNATGGCNCARGTNACNGARAARYTN ACNGAYCARATHGARGGNTCNTCNAAYATHACNTCNAARGARGCNGCNAARYTNATGAAR ATHCAYAARGCNGARATGGAYCARTAYMGNGCNAARCARCARMGNGARAARCARGCNATG YTNGCNMGNYTNCARGARAARYTNCARCARMGNYTNGARGCNGCNGAYGARAGYGARGCN MGNGAYCARAARGARCARGARGCNYTNAARGARCARCARATGGCNACNYTNGARAARGTN YTNGCNTCNAAYYTNGAYYTNTCNGARGAYGCNAARGAYMGNATHATGMGNGARCAYGAR CARAAYATGCARTCNYTNTCNAAYCARYTNATGCARAGYAARATHMGNCARCARAARAGY YTNGARATHAARYTNAAYCARMGNAARGCNAARYTNGCNGARYTNAARCARAARMGNGAR GARGCNMGNCCNGGNAGYAGYAARAARGARAARTCNAAYYTNGARAAY------ATGGCN ACNAGYYTNGAYGARCARATHGCNAARGARGARGCNAGYTTYGARGARGCNMGNCARTCN GCNGTNGTNGARYTNMGNAARCARYTNGCNCARGARACNGARGCNGCNYTNAARCARCAR GAYGARGARATHGGNYTNYTNATHGGNMGNYTNCARGTNGGNCARGCNMGNMGNAARGCN ATHATHGARAARCARGAYGCNGTNYTNAARGAYYTNCARGAYAAYYTNGARMGNCARGTN TCNTCNGCNAGYGGNYTNMGNCCNTCNATGACNGAYCARATHYTNAAYCAYCAYTAYGCN AARGTNTCNCAYYTNAAYGAYCARYTNCARMGNCAYMGNGAYGAYCAYGARMGNMGNATH YTNGARAARYTNGCNCARAARMGNGCNGARAARGARTAYCAYATHGARTCNCARYTNGAR AARGARGCNCAYACNGARTAYTCNGARAARCARAARMGNGGNGCNGGNTAYGCNAGYYTN GCNYTNATGCARTCNTTYYTNGARCARMGNCAYGCNAARGCNYTNAARGARYTNGARYTN GARATGAARGCNGARYTNGARAARAGYAARAAYGARYTNAAYCARCARYTNGARGTNGAR YTNMGNAARGARYTNGAYTCNGARMGNCARAAYYTNYTNACNCARYTNGCNGCNGTNAGY GAYATHTCNCARGCNGAYYTNCARAAYGCNGTNACNGCNGCNACNGCNGGNCARACNGAY TCNAARTCNGCNAARMGNYTNGCNAARGAYYTNAARGAYAAYGTNGARMGNGTNMGNTCN GCNATGTCNYTNCAYMGNGARGARCCNMGNGAYGAYGAYTTYGGNTAYAARMGNAGYAAR ACNGAYYTNGARAGYAAYCARCARTAY------AARAARGGNMGNAARGGNTCNGCNGTN TCNACNCARMGNMGNGGNAGYGCNMGNCARGCNTTYGTNGAYGARGAYGARGAYGARGAY ATGGAYATHYTNTAYATHTCNYTNTGYTTY------ATHACNATHTTYGCNTCNTCNYTN GGNYTNGAYCCNATHGARYTNAARTTYGARAAYGCNTCNMGNGTNGAYGTNYTNGARGGN GCNACNGAYGTNATHTTYMGNTGYCAYYTNAAYMGNCARYTNATHTTYYTNTTYGARAAY CARGTNAGYYTNGTN------------CAYACNAAY------CCNGCNACNAARAARGAR ACNACNYTNGCNACNTCNACNACNYTNYTNGARGGNTCNCCNGARTTYTAYGARAAR--- GGNGTNAARGARGTNGAYGARAAYAAYYTNATH---TTYGARTTYAARTTYYTNAARGTN MGNAGYGGNGAYGAYGGNTTYTAYAARTGYAARGAYGGNGCN---TCNATHACNTCNGAY GAR------------------AARGARYTNYTNGTNCAYMGNCCNATGTCNTCNYTNAAR YTNAARYTNGGNGARTAYGAYGCNGTNGARGAYTCNCCNTCNGAY------------CCN YTNGCNATHGAYCAYGGNAGYTAYAARYTNGCNTGYATHGCNGARGGNAGYAAYCCNGGN ACNGARGAYATHCAYYTNTTYTTYAAYGARAARATGATGGARCAYGAYAARCCNGTNATH GARCARATHGARGARGCNGAYGGNMGNYTNTTYAARTCNGARYTNTCNGCNGAYGTNAAY GTNATGGTNAAYAAYTCNGGNCARGARTTYGTNTGYCARGCNMGNGAYTCNACNGGNCAR CCNAARACNATHAARYTNAAR------ATHCARGTNAAYATHTAYGAYCCNATHGTNTCN TGYAAYGAYTCNGARGCNCAYYTNGGNCARGCNAAYCCNGTNYTNTAYTGYACNGTNAAY CAYACNGGNYTNGARGTNACNGGNTAYGGNTAYCARYTNGGNGAYACNYTNGAYGTNATH AARGCNGGNGCNGAY---------CAYCCNAARAAYATHCARGTNACNGTNTCNAAYGTN TCNCCNGAYGTNGCNGTNGTNGCNYTNGAYYTNCAYAARGCNGARCARGARTAYTTYAAY AARAAYTAYTAYATHGTNGTNTAYATGGCNGGNGGNCAYAARAGYAARGARAGYGTNMGN YTNCAYATGAARGARGCNCCNGTNACNAARAGYGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AAYGGNGARYTNMGNMGN MGNAGYAGYCARACNTCNACNCAYAGYGAYCARYTNCCNTTYGCNGTNATHAAYMGNAAY GTNATGMGNMGNGAYTCNTTYGARATGCCNCARMGNACNATHATHGAYTCNCCNMGNCCN ACNMGNTCNMGNTCNYTNCAYAARTCNCCNGTNGARGTNGCNGCNATGCCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---YTNYTNTCNCCNACNYTNGAYCCNTAYCCNGAYTAYTTYYTNTCNGTNYTNCAYAAR MGNYTNATHGARGGNCCNGTNTTYAAYGTNACNGTNGARCCNAGYACNCCNGARYTNMGN ATGTAYGCNCAYTGYACNMGNATHTCN---GGNATGTAYAARACNGGNGCNATHACNYTN GCNTAYYTNAAYACNAARAAYGARTCNYTNACNGTNAGYYTNATHCARTTYTCNACNYTN CAYTTYGAYYTNTAYATHYTNACNCCNGGNGAYTCNGCNGGNYTNAARTCNAARTTYGTN AARYTNAAYGGNGARGTNYTNAARATGCARGGNTCNTCNYTNCCNTCNTTYAAYCCNAAR CCNTGGAARGGNGAYATHGTNYTNGCNCCNYTNTCNTTYGGNTTYATHGTNGTNCCNGAY GCNAARTCNGCNYTNTGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNCCNAARCCNATHTGGYTNGAYGGN CARTAYCAYGARATGMGNATHGAYGCNCCNCCNMGNAAYGTNYTNGTNGAYGGNTCNATG MGNGGNTTYCARATHGAYGGNMGNGAYAAYATGYTNYTNGTNGAYMGNATHGARAARGGN CCNTAYGGNGGNCCNCCNMGNAARATHYTNATHGTNGGNGTNGARCAYGARATHAGYTTY CARTTYCCNCCNMGNACNATHYTNATHGAYGGNAARCCNTGYGARYTNAARYTNGAYAGY AARATHCCNTAYGTNGTNATHGARGGNAARCCNCAYGGNATHMGNTTYGARGGNGARCCN MGNAAYATHTTYATHAAYGARCARCCNTAYACNATHCCNYTNGAYMGNGCNGARAARATH MGNATHGGNCARMGNCCNACNTAYATHGCNTTYGGNGGNCCNGCNCAYGARATHATHATH GAYGGNAARTGGTTYGARGTNAARTTYGAYAAYACNYTNAARAAYATHCAYYTNGGNAAY MGNCAYTTYMGNGTNMGNATHCCNGGNCCNYTNCCNMGNGTNAARATHYTNGAYCARYTN CCNATGAAYTTYGAYGTNTCNGGNYTNATGGTNAARAAYTCNACNGARGTNGARMGNCAR ATHCCNTCNACNGTNYTNCARCCNAAY---------------ATGCCNGGNYTNGGNYTN CARMGNCCNGGN------------------------------------------CARATG CARGTNCCNAAYCCNATGGCNCCN------------------MGNCCNATHACNTCNGAY CARATHAARYTN---------------------------------------CARMGNGCN CARCARYTNYTNMGNCARYTNCARAAYTCNCARTTYGCNCARAAYCARTCNATHTTYCCN ------------CCNGGNYTNATHCAR--------------------------------- ---------------------------MGNYTNCARGCNGCNMGNCCNGGNYTNATGCAR CARCARYTNAAYGCNGGNATHGTNYTNCCNGGNATHATHCARCCNMGNATG--------- ---------------------------------------------CARCARACNGTNGGN ATHMGNAAYGCNYTNCARCARCARACN---------------AAYATHACNTCNCARGGN ATHATHAAYCARGTNGCNAAYACNATHGTNCARTCNGTNCCNGCNGTNATHCCNGGNAAY ATHAGYTCNYTNGGNCARTCNGCN------------------------------------ ------ATHAGYCARGCNTCNGCNYTNYTNACNGGNYTNCARGGNTCNGGNATHAAY--- ---ACNAAYATHACNGTNCCNAGYGCNATHACNACNGCNGGNAGYATHCCNGCNYTNTCN AAYTCNCARGCNTTYTCNGAYCCNGCNYTNACNGGNGTNYTNGGNYTNACNMGNYTNTCN GCNGCNCCNGTNCARAGYACNCCN------------------AGYACNGCNGCNGTNCCN ACNTCNAGY------------CCNGTNGAYATHAAYAGYYTNYTNAGYAAYYTNGTNAAR GCNGGNYTNATHAARGAYTCNAARTCNGAYACNGCNCCNGCNGCNCCNCCNCCNGTN--- ---------------GCNGGNCCNCCNCARTCNTCNAAYTCNACNGARACNATHAARGAY GTNTGGCCNGTNAARACNAARGGNCAYATHCCNGAYYTNTCNGAYTTYGAYTCNGAYYTN YTNAARATHCCNTAYCARMGNGTNGTNGAYGARYTNCAYCARGGNATHCARTGYCAYACN TGYTCNGCNMGNTTYACNGAYGAYGAYCARGCNAARTAYAARGCNCAYYTNGAYTGGCAY TTYMGNCARAAYAARYTNGARCARGARATGGTNAARGTNGCNAARAAYMGNAARTGGTTY TAYACNATHCCNGAYTGGATHCARTAYGARGARYTNGARGAYAGYGARGARAARTCNMGN AGYGARATHTTYGARCARATGMGNYTNGTNAGYGARCARACNTCNAGYAGYGCNTTYGCN ATGGAYCCNCARMGNYTNMGNGCNYTNGARGGNAARGAYGTNGTNACNAAYCCNGTNGCN ACNGGNGCNGARGGNGARGAYGTNTGYGCNACNTGYGGNGAYCCNTTYGAYCARGTNTGG AAYGARGARACNGARGARTGGATHYTNAARAAYACNATHAARGTNAAYGGNAARACNTAY CAYCCNATHTGYTTYGARGAYATGCARGARACNCCNACNCCNATHACNGAYYTNGCNMGN AAYCCNYTNGAYATHGARATHAARCARCARGARAARATHGARGARGARAAYCARCARATH GAYACNAARCCNGAYATHAARAAYATHTCNGARCAYCARGCNAAY--------------- ---------YTNGAYACNGCNGGNATHTCNAAYATHAARGTNGARTCNCARGCNTCNGAY AGYTTYGTNGARGTNAARAARGARATHGTNGARGARCCN---GARAARGCNGTNGTNTCN GARCCNTTYATHAARATGGARCCNYTNTCNGARGGNGGNATHCCNGGNTCNAAYACNAAY GAYAGYGARATHCCNACNTCNGCNYTNAAYAAYGCNGGNACNAAYACNGCNMGNAARGTN ATHTCNGTNTGYCARGARGAYCCNAAYTCNCCNTGGGARATGGAYTCNAAYCCNACNCCN GARYTNTCNMGNACNCCNAGYCCNYTNCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CAYYTNTTYGTNGTNACNCAYAGYGGNATHGARACNTAYACNTCN MGNTGGGCNGCNGTNGCNYTNGARTTYGTNGCNYTNYTNTCNAARATGGARTAYGCNTCN AGYTCNGARGARACNGTNTGGAGYTTYTAYATHGTNCAYAGYCARAGYATHATHGAYCAR TGYAARGAYATGYTNCARTTYGCNGARAAYATHMGNYTNACNGGNCCNACNTCNTAYGTN CAYYTNYTNCARGARGCNGAYYTNYTNYTNACNACNTAYATHGCNCARYTNAAYACNAAR AAYCCNGARYTNGAYGARTGYATGACNMGNGTNAARMGNYTNYTNGGNGAYGTNTAYGCN CARCCNGGNGARGARAAYTGGMGNYTNTGYCAYTCNTAYTAYAAYAGYYTNGGNATHAGY ATHGARTAYGTNGTNAARCARGCNATGGARCARGCNAAYCARAARTCNCCNCCNGARTTY GGNAARGGNATHYTNGAYTTYYTNGAYAARMGNYTNTTYGGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GCN YTNTAYTCNAAYTTYAARATHGARGGNGARMGNGAYAAYTAYMGNYTNCAYGTNTCNGGN TTYAGYGGNAGYGCNAARGAYTCNYTNATGMGNCAYAAYAAYAARCARTTYAGYACNGAR GAYMGNGAYCAYGAYAAYMGNMGNGAYGCNAGYTGYGCNAGYGARTGGGARGCNGGNTGG TGGTTYGAYAARTGYTGGTAYGCNYTNYTNAAYGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TAYTCNTCNTCNATHGGNGTNCARTCNCARCCNGCNTCNATGTCNGGNYTN AGYGCNGTNCCNGTNTCNAAYCCNAGYTCNTCNCCNMGNCCNAGYATHYTNMGNAARMGN GARATHGARAAYGARAARMGNATGAARACNYTNCCNAARMGNYTNYTNTAYYTNYTNMGN TAYGGNGCNYTNAARGARGGNYTNGAYGTNGAYATHAAYGGNTAYGTNGAYATHACNGAY GTNYTNAARGTNCCNYTNATHAGYACNTAYTCNCARGARGARATHYTNAAYGARGTNAAR ACNTCNGTNTCNTAYMGNAAYATHCAYMGNTAYGARTGGMGNGARAARGAYAARAARACN TTYATHMGNGCNGCNTAYYTNMGNMGNTTYGARMGNAGYCCNGTNCAYCCNGGNACNCAR GTNAARACNYTNGCNGARACNAGYATGAAYTGYGTNYTNGAYAAYYTNGAYATGTTYGAY YTNGARGARTTYCARGAYGARGAYACNATHAARYTNATGATHCAYMGNYTNAARMGNAAR AARACNYTNTCNAAYAARGCNYTNTCNGTNYTNYTNGTNCCNACNYTNACNMGNATHGAY YTNGARGGNATHTAYYTNACNAAYAAYACNYTNMGNYTNYTNTGGACNCARTGYCCNCAY YTNMGNGGNGTNAGYYTNAARAAYTGYGGNTAYATHGTNACNGAYGCNATGYTNACNCAR YTNGTNAARAAYYTNCCNATGYTNGARCARYTNAAYYTNAGYMGNTGYGTNCAYYTNACN GAYAARTGYYTNGCNATHATGTCNAARMGNYTNACNCAYYTNAARGTNYTNCAYGTNGCN GGNGTNCCNTCNATHAARCCNAARTCNGTNCAYACNTTYYTNGAYTCNGCNAARAGYYTN ACNTTYYTNGAYGTNTTYTAYATGAARACNACNCARGARGARTTYGAYAGYYTNACNGAR AARGCNAARACNYTNGGNGTNMGNYTNGTNYTNCAYTCNCCNAARGARAARYTNCCNYTN AARGARGARMGNTTYTCNGAYGARGAYGARAARGGNGARAGYGAYAAYGAYGGNGAYGAY GAYGGNGGNGGNMGNGGNGAYGAYGAYGAY---GGNTGGACNGTNATHCARAARMGNCAR GAYGGNAGYGTNGAYTTYTAYMGNGGNTGGGARGAYTAYMGNMGNGGNTTYGGNAGYYTN GARGGNGARTTYTGGYTNGGNAAYGAYAAYATHCAYTAYYTNACNTCNCARGARCCNACN ATGYTNMGNATHGARATGGARGAYTGGAAYGGNAAYTTYCAYTAYGCNGTNTAYGAYTAY TTYMGNGTNGAYAGYYTNAARGARAAYTAYMGNYTNCAYATHAGYGGNTAYCAYGGNAAY GCNGGNGAYTCNATGACNTCNYTNTAYGARAAYCAYGAYGGNATGCCNTTYAGYACNAAR GAYAARGAYAAYGAYGGNMGNTAYTAYGAYTCNTGYGCNAARCAYTAYCARGGNGGNTGG TGGTTYAAYAAYTGYTTYGARGCNCAYYTNAAYGGNAARTAYGTNCCNTAYATHGGNMGN AARATHAGYYTNGTNTCNAAYTCNGARYTNMGNTAYGARGGNATHYTNTAYACNATHAAY ACNCARGARTCNACNATHGCNYTNCARTCNGTNMGNTGYTTYGGNACNGARGGNMGN--- AARYTNCCNGARATHCCNCCNTCNAGYGARGTNTAYGAYTTYATHATHTTYMGNGGNCAR GAYATHAARGAYYTNACNGTNYTNGARTCNGGNAAR---CARCCN---------GGNGCN GCNACNGAYCCNGCNATHGTNTCNATHAAYCARMGNCCNTCNGGNAARGAYGGNAARGGN GGN---------AARGGNGARATHCCNTTYGGNGGNCCNGCNATG--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ACNCAYYTNGGNYTNACNGAYMGNCARGARMGNGARCCNTAYYTNAAYTTYGTNYTN CCNCAYTTYCCNCAYYTNATHTCNYTNACNGTNAAYGGNMGNGAYATHCAYTCNGAYGAY TGYATHGCNYTNAGYAAYTTYTGYCCNAARYTNCARGAYYTNGTNTTYGARYTNAARTCN ATGMGNGAYCAYGAYTGYYTNTTYGAYTTYTAYYTNCAYCARCAYAAYTCNYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNCARYTNYTNYTNTCNCARAARGGNGARMGN GTNAAYGTNYTNTTYATGGAYGCNCAYCCNGARAGYMGNYTNGAYATHATHTGGTCNAAY YTNTTYGGNAARATHATGMGNGCNGGNMGNYTNCARYTNCCNGTNACNTTYGARAARYTN GTNTGGGGNATHCARGGNTAYMGNAGYCCNYTNAAYGAYCAYCAYTCNYTNACNGTNCCN TAYYTNGARGARTTYMGNCAYTTYTTYYTNACNMGNCAYGGNGTNAAYTCNAAYCAYGTN YTNGAYTGYMGNCAYYTNAARGCNYTNGTNATHTGGMGNCAYGAYCAYGCNACNCAYCCN MGNAAYAARYTNGGNCARGTNGTNMGNAARTTYTCNAAYGARAAYGARATHYTNAARTCN TCNACNMGNGAYGTNAAYGAYACNGARATHGCNGTNGGNATGGTNYTNGARACNATGGAR ATGAARCARCARYTNACNYTNGTNTCNAAYTGYGAYTAYCCNGCNGARGTNGARGTNTCN TAYGARGARTTYAARTTYGTNGARCARATHYTNCCNAARGARACNGTNCCNGARATHCCN CARCAYTCNTCNTAYCCNACNCCNTCNGGNTGGAGYCCNCCNAAYGAYGARATHMGNTCN CARCARCCNTAYYTNGTNMGNMGNACNAARAAYCAYGTNYTNCCNGTNTAYCCNGGNCAR MGNGARGTNTGGAARAAYATHAARCAYCAYGTNGTNATHAARAAYATHGARGGNGAYATH TGGAARYTNGARTCNGAYYTNMGNCARCAYYTNCARGAYYTNACNCARACNGAYAARATH YTNACNCARGTNCAYGARGTNAGYMGNTGYATHMGNGTNMGNGGNGARCAYACNGCNGAY GTNGCNCARTTYYTNYTNGAYAARGGNATGGARGARGTNGARYTNTCNACNGARATHGCN GGNGAYYTNGARYTNTCNTAYATHCARYTNCAYCCNAARAARAARYTNTGGAARGTNTTY AARYTNATHGGNACNMGNTCNTTYAARCARGAYCCNMGNGTNATGMGNTCNMGNYTNATH MGNGARGTNCARTCNAARTGGAARGAYGGNTTYATHTAYGGNAAYATGGGNTAYTAYTGY GGNGCNGTNTGGYTNMGNATHCAYTTYGAYACNTCNAARMGNACNMGNAARAAYTCNYTN CARAARGCNGGNTAYAAYCCNAAYAAYTCNGTNTTYYTNYTNCAYTTYCARGGNTCNCCN TAYYTNATHATHAGYMGNACNMGNGTNAARGARACNACNYTNYTNACNGARTCNYTNACN AARGTNTTYTAYGCNGAYAARYTNAGYTAYYTNCARYTNTCNGAYMGNCAYYTNYTNTCN YTNGCNAAYATHGCNYTNAAYAARAAYTTYGARTCNTCNACNGTNCARAARTTYAARGAY YTNGAYGGNTGYGARAAYCCNYTNYTNCAYAAYGAYMGNAARMGNAARCARGCNGAYGAY ATHTTYGARGGNGAYGARAAYATHGTNGAYYTNAAYGTNGCNGARAARMGNGARMGNYTN ATGCARGTNGAYCAYAARTTYGGNTCNGGNTCNCARCCNACNYTNGARAARATHGARTAY AARTTYAGYATHGGNTTYCAYGGNCARGARGTNACNAAYYTNGAYTGYAARACNCARGTN GARATHAARGGNCCNTCNGTNYTNAAYGGNYTNAARCARYTNGCNAAYMGNGGNTTYATG ACNTTYCCNYTNCCNAARCAYYTNACNAGYGTNCARTCNCARCARMGNAAYAAYTTYACN ATH--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNACNYTNAAYACNAGYGTN ACNTCNGCNAARAARCARACNTTYGAYYTNAARGCNAGYYTNGCNAARCCNYTNACNTGG AARCCNCAYACNGGNAARYTNCARCCNGTNGAYTTYAAYGCNAARCARACNGCNCCNGTN TCNMGNCCNGTNGCNAARGTNAAYTCNCAYMGNGTNMGNYTNAGYMGNGAYTCN---GCN AAYAARATHMGNCCNGTNCARGCNAARAAYGTNMGNMGNGCNGCNCARYTNGAYMGNMGN AGYAAYCARAARTAYGTNGAYATGATGAARMGNMGNGGNYTNATGGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNATGGARGARATGACNACNATGCAR AARGGNMGNATHMGNYTNGAYGTNGGNGGN------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGGAYTTY GGNTCNAARTTYGTNTAYYTNGGNAAYGARCARGARGAYGARGARGARGTNAARATHTCN GARGTNGAYAAYGTNGTNYTNTCNGAYAGYGAYGTNAGYGAYGAYGAYGGNGARACNTGY YTNYTNGAYATHYTNGAYACNGCNGGNCARGARGARTAYTCNTCNYTNAARGAYYTNTAY GTNMGNGARGGNGAYGGNTTYGTNATHATHTAYAGYATHGTNGAYCARGCNAGYTTYAAR GARGCNGARGCNATHTTYMGNTGGYTNAARMGNYTNMGNGAYAAYGARACNTGYCAYGCN NNNYTNGTNGCNAAYAARCARGAYYTNAARGAYGAYGCNGAR------GTNAGYGAYAAR GARGGNAARGAYYTNGCNGARAARYTNGGNATHCCNTTYTTYGARACNTCNGCNAARGAY GGNAGYGGNGTNATHGAYGCNATGAARGGNYTNGTNMGNATHATHCCNMGNACNGGNAGY GAYTAYAARGTNGTNATGYTNGGNAGYGGNGCNGTNGGNAARTCNAGYATHACNYTNMGN TTYGTNAAYAAYGTNTTYGTNGAYGAYTAYGAYCCNACNATHGARGAYTCNTAYMGNAAR ATGATHTCNGTNAAYGGNYTNTCNGCNGTNAGYAARGAYACNMGNAARGCNGCNAARAAR GCNAARAARTCNAARAARACNAARMGNTCNGCNMGNCARMGNACNAAYAAYAGY------ ---------MGNCCNAARTCNGCNGCNAARAGYGGNGGNGTNTTYCARAAY--------- ------------YTNTTYGGNAGYATHAARGGNGTNGTNGGNMGNCCNCARTCNGCNCAR GTNCCNCCNCCNCCNCCNCCNCCNATGCARGTNCCNGTNCCNYTNCCNATHGTNAARGAR MGNAARACNGAYGCNAAYGTNGTNYTNATHGCNYTNMGNCARYTNGGNGARGARCCNAAR YTNGTNACNGGNGAYCCNATHCARTGYAARAAYTGYGARGCNGTNYTNACNGARACNGCN GTNYTNGARACNGAYGGNGAYAARAARATHTGGAAYTGYGARTTYTGYMGNCAYGCNAAY MGNGAYYTNGARATHTCNGAYGAYGARATHCCNAARGGNGARTGYYTNGAYTAYATGYTN TCNCCNGCNACNAARCCN---------GAYGTNGAYGARGCNGCNGCNTCNGAYGAYTGY AARAARATHACNACNCCNGGNGTNATHGTNTAYTGYATGGAYATHAGYTCNTCNATGGCN GCNACNTGYGAYATHCCNGARTCNCARTCNTCNTGGMGNCARGARMGNYTNGGNGTNCAY GAYTCNAAYMGNGTNACNMGNYTNGARTGYATHCARACNGCNGTNGARMGNYTNGCNGAR CARYTNAARAGYGARCARCCNGARAARCARATHYTNYTNGTNGTNTTYAGYTCNCARGTN TAYGTNAARGCNGGNGGNTCNATGGARAAYYTNCCNTCNTTYACNAAYGTNGAYAAYGAY ACNTTYGARCARYTNYTNGCNAARGGNGTNMGNYTNTGYGAYAGYTAYGCNYTNAARCCN YTNYTNGARTCNTAYGAYGARGTNACNAARGCNGTNAARGCNYTNMGNACNACNGGNTGY ACNGCNYTNGGNCCNGCNYTNTCNATHTGYATGGGNTTYGCNAGYTCNATHCCNAGYTCN GARATHGTNYTNTGYACNGAYGGNGARCCNAAYGTNGGNGTNGGN---GTNMGNGARGGN GCNGARTTYTAYCARCARGTNGGNACNTAYGCNMGNTCNAARAAYGTNACNATHAAYATH YTNGCNGTNGARGGNGCNTCNGTNGGNYTNCARTCNGTNAGYGCNGCNGCNGARTAYTCN GGNGGNACNACNAAYAARYTNAAYCCNGCNGARATHGTNMGNCARYTNMGNTCNATHGCN CARAAYGARGTNGTNGCNACNTCNGTNACNGTNMGNTTYTTYYTNCAYCCNGAYTTYGTN TTYGAYGARCCNGAYTAYGGNGAYAAYYTNAGYCARYTNGARAARGARGTNGGNTCNGCN MGNYTNGARACNGAYYTNACNTTYMGNTTYAARYTNMGNGAYCCNAGYAARAARGARATH ACNTCNGTNCCNTTYCARGTNCARATHAAYTAYACNMGNACNAAYGGNATGAARTGYYTN MGNGTNYTNAGYAARMGNAAYGARGCNACNGAYTCNMGNCARCARATGGARGARAAYATH AGYGCNACNGTNATGGGNGTNTCNGCNATGAARACNACNGCNCARYTNGCNAARAGYGGN AARGGNGTNGARGCNCARCAYATGYTNAARAAYGTNAARMGNATGGTNAAYMGNGGNGCN AARACNAGYGARCARAARGARGCNAARYTNGCNTTYAAYAGYGARATGGCNGCNTGGGAY GAYGAYYTNACNTTYAARAAYAGYATHTAYGARGTNCCNGGNGGNATGCARTCNGAYATG GCNACNAAYATGATHCARCARGCNCARGTNATGAAYTCNCAYGTNGGNCARACNAARTTY TCNAARGTNATGGCNMGNAARAARATGGGNGCNTCNAGYAARGCNGCNTAYTAYTCNTAY AARAAYGAY--------------------------------------------------- ------------------------AARTGGATGATGTAYTGGATHGTNTTYGCNYTNTTY TGYAGYATHGARACNTTYTCNGAYGTNTTYYTNTCNTGGYTNCCNTTYTAYTAYGARYTN AARATHATHTTYGTNATHTGGATGYTNTCNCCNYTNACNCARGGNTCNAGYTTYATHTTY AARAARTTYGTNCAYCCNCARYTNGCNMGNMGNGARAARGARATHGAYGARATGATHGCN CARGCNAGYAARCARGGNTAYAGYACNYTNYTNTCNYTNGGNTCNAARGGNGTNAAYTAY GCNTCNCARGTNGTNATGMGNACNGCNATHATGGGNCARTCNAARYTNGTNGAYCAYYTN MGNMGNAGYTAYAGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GGNGGNACNAARYTNAARGCNGTNATHGGNTTYGAYAARATHGTNGGNATHYTNAAYAAR TAYAAYGCNCCNCCNGAYATHYTNGAYAARTAYYTNGCNYTNATGGAYGAYCCNGARGCN MGNYTNAAYYTNGCNAARAARGTNAAYTGYCAYAARACNGTNATHGAYACNTAYGCNTCN YTNAARGAYMGNCCNTCNYTNGARAAYTAYGCNTCNCARYTNGAYMGNTAYTCNAARGAR GGNYTNTAYGCNTAYGAYGTNYTNAAYGGNYTNGTNGTNAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GAYGARATGAGYAGYTCNAAYAGYGCNCARGARACNAGYTCNTCNGCNGCNTCNCCNCAY TCNACNCCNGARYTNAAYATGGARGCNGARGGNAAYTAY---CCNAAYACNGAYCCNTCN AARTGGAGYGTNACNGARGTNTAYGARTTYGTNYTNTCNATGCCNGGNTGYTCNGAYTAY GCNGAYGAYTTYMGNTCNCARGARATHGAYGGNCARGCNYTNYTNYTNYTNAARGARGAY CAYYTNATGACNGCNATGAAYATHAARYTNGGNCCNGCNYTNAARATHTGYGCNAARATH AAYTCNYTNMGNATHGAYCCNYTNCCNTTYCAYACNTCNAGYTAYCAYYTNGTNAAYMGN MGNAARGAYMGNGCNGTNATHAARCAYYTNTAYTAYGTNGAYTAYGARAARACNYTNAAR CAYTCNCARAGYCCNYTNGTNGARYTNCCNGAYTAYACNTAYCARGAYGGNMGNCCNACN GARATGACNYTNTGYCAYCARMGNAARCARGARAARAAYYTNAAYYTNGCNAARCARGTN GTNAARYTNATGGARGARGTNAARYTNGCNCARAAYCARTTYACNAARCARGARGARGCN AARYTNMGNCAYGARGARAARMGNMGNCARTCNCARYTNAARCARAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGTCNYTNGARYTNGTNTCNAARTGYYTNGARYTNGAY------YTNGCNGTNAARGGN CARGGNTCNAARGGNAARAARTGYAARAARYTNAARATHAAYAAYGCNATGGARATHATH CCNACNAAYMGNCAYGGNGTNTGGAARGARYTNMGNAARGTNMGNAARAARCARYTNAAR GARATHAARAARAARMGNAARGCNGARATHTTYAARTCNGCNATHGARYTNTAYAARGAY AARTAYGAYGTNGAYCAYACNGAYAGYAAYGTNGARACNYTNYTNAARATHTCNAARYTN GGNAARGTNGAYGCNAARTAYGCNGARAARATHYTNTAYCAYCARCCNTGYMGNYTNTCN MGNGAYATHAARCCNGGNACNGARGTNACNGARCCNTCNACNGTNTTYACNGARGAYGAY TTYGARGCNTTYGCNAARGAYTAYCARCCNAAR---------ATGTCN------GTNCCN CAYGCN------------CCN---CCN---YTNGGNGGNAAYCARCARGAYMGNCARAAY MGNAARYTNYTNYTNGARCAYATHCARGARCARAARAARMGNYTNCARCAYGGNCAYCAY TCNTCNTCNGCNAGYCCN---ACNCCNTCNATGAGYTCNAGYCCNGCNACNATGGTNAGY AAY---AAYTCNTCNACNCCNGGNYTNTCNGCNGCNGARTAYGCNTCNATHAGYAAYCCN CARCARMGNACNGCNYTNCARCAYGCNCAYGCNAAYTCNGTNGGNTTYTTYATHACNCAR GAYTCNTCNTTYGGNAAYYTNATHYTNCCNGTNYTNCCNMGNGTNCCNGAYGCNAARACN GARACNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNGAYAAYAAR--------------------- ---------------------------TAYATGCAYGARTAYTAYGCNTCNGCNGCNGCN ACNGCNCARAARATG---MGNGCNTCNGGNYTNGGNAAYTTYACNTAYACNACNCAYCCN TGGYTNATGCARMGNTTYYTNATGTGYCCNTGYGCNGCNGAYGARGGNAGYTCNTGYYTN GCN--------------------------------------------------------- ------------------------------------------------------------ ---------MGNAGYYTNAAYAAYAGYTTYGARCCN------------------------ ---------CCNYTNMGNTGYCCNACNGCNGAR--------------------------- ------GARATHGCNAAYTTYTCNGCNGCNGCN--------------------------- ------------------MGNMGNGGNGAYATHGCN------------------------ ------------------TGG---AAYGCNGCNCCNTTYAAYATHCAR------CCNGAR AAYATGGCNCCNGARYTNTTY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GARGAYGGNACNGCNACNCCNMGNGCNGGNGCNGCNGGNCARGAYATH TCNAARGARGCNTAYAARGCNAARATGGCNGARAARMGNMGNCARGCNMGNGARAARGCN GARAARGARGCNGARGARGARMGNAARMGNCARGARGARGARMGNYTNGCNGARGARGAR MGNCARMGNCARGARGARGARGARCARMGNMGNYTNGARGARGARACNATHMGNYTNGCN GARGCNGCNMGNAARGCNGARGARGARMGNYTNCARMGNGCNATHGARGCNGARGARAAR MGNAARAARGARGARGCNGARMGNATGGARCARGARMGNAARGCNAARGARGARGCNGAY MGNAARGCNAARGARGARGCNGARMGNATHGARAARGARAARCARGARMGNGCNAARAAR GARGARGARGARMGNYTNGARMGNAARAARAARYTNGARATGATHATGAARMGNGTNAAR ACNGAYCCNGCNCAR---------------------------GAYACNTCNGTNAARGTN GARAGYCCNGTNAARTCNTCNGGNAGYTCNCCNAAYMGNAGYGCNYTNGCN--------- ---TCNCCNGARGTNCARGAR---------ATGCCNCCNTTYGGNCARGARCARGARGGN TCN---------------------------TCNACNGCNGARGAYGGNAARCARAAYCCN ACNCCNCCNCCNGCNATHCCNTCNGARGAYGCNACNGARAAYCCNGARATHTCNACNCCN TCNGARCCNGCNGCNYTNACN--------------------------------------- ------------CAYGTNGTNMGNAGYGCNTCNTCNGGNGAYATHATHGAYAGYGCN--- GCNGAYGARGAYAARAARGARATGGARAARGGNGAY---------AGYYTNGGNGCNYTN AAYACNCCNGTNAARTCNACNAAYGGNAAYTCNTCNGARCCNTCNTCN---ACNGARGTN AARTCNMGNTTYAARTCNCCNYTNYTNCARCARYTNGTNGARAAYAARGGNGGNTCNGAY TCNGCNAGYGGNACNCCNAARTTYAARTCNCCNYTNYTNCARAAYYTNYTNGGNAARACN AARGTNGGNGCNMGNATGGGNYTNTCNGCNAGYATGGGNGAYYTNAAYYTNAAYAARGAY AAYAGYAGYTCNGCNGCNAARGARGTNAGYGCNYTNCARCARCARGARGGNTCNAGYCCN GCNTCNAGYCCNGCNAGYTCNAGYAARGARATHTCNAARGCNGGNCARGAYGARGAYAAR GAYGTNGAYGARTCNGTNGGNTCNTCNGCNTCNTCN------ACNTCNGGNAAYGAYCAR GARTCNTTYGARGAYCAYATGACNAAYGGNAARTCNTCNGCNTCNGAYGGNMGNTAYGAY GAYGCNGTNATGACNAARTTYTCNCCNCARGAYAGYAARATGTCNGAYTCNGCNYTNGGN TCNAGYATHGARCCNCARCARGGNGAYYTNGTNGAYTTYTCNGCNCCNGAYTCNGGNYTN TCNAAYGGNCAYGGN------GCNCARCCNGAYYTNATGGARGAYTCNAGYATHAGYGTN CARACNCCNGARGARACNGTNTCNGCNCCNTCNGCNACNACNTTYAAYGGNCARTCNTCN TCNCARGAYGARACNGARGARGARGGNGARAGYGGNMGNTTYGARGARYTNATHGAYYTN CCNTAYTCNTCNAGYAAYGCNACNAGYAARGCNGCNGTN---TCNCCNATHATHGCNTTY GARGARAAYAGYYTNMGNACNGCNGAYGTNGGNGARTCNATGTCNGAYGTNGTNATGATG ATGGARYTNCCNCCNGGNGCNAAYYTNGTNGCNAARAARGAYYTNTAYYTNCARGTNGCN GGNATGTGGACNGAYAARCCNGTNGTNAARYTNGAYAAYATGYTNTAYGCNGGNAARATH TCNGARACNATGGGNTCNGAYTTYTTYGTNGARTAYGAYGGNGAYGARYTNACNCARTCN CARCARAARAARGAYMGNGAYATGYTNGTNTCNCARACNGTNYTNACNYTNGARCCNGTN TAYYTNGARGARAARATHAAYTCNAAYGGNCARGTNYTNGARTCNCARTCNCCNTGGMGN YTNTCNTTYATHACNGAYGCNYTNTGGGGNATHATHAAYTTYATHGTNYTNTTYTTYCAR ACNATGATHAAYCCNAAYAARAAYAGYMGNGGNGAYAAYTAYTCNTCNGAYTAYMGNMGN CCNGGNGGNGGNGGNCCNCCNACNMGNMGNATGGGNGGNTTYMGNGGNGGNMGNGGNGGN ---ATHTTYACNAARAARGGNTAYGCNACNATHTCNTGYTCNAARTGYCARAGYTCNAAR AAYCCNGGNTGYGARATHCARCCNCCNCCNCCNACNACNTGYGTNGCNTCNGGNAGYGGN ATHACNCARTCNTGYTCN------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GAYATGTTYGGNGAY GGNYTNGGNAARAARAGYYTNATGCCNGARATHAGYCARGCNTTYACNGCNGTNAARAAY MGNYTNGAYACNTCNYTNTCNAAYGAYGARGAYTCNCARMGNTAYYTNTTYGARGARGCN MGNGTNAGYGCNGCNACNATHYTNCARCARYTNAGYMGNATHATHTAYTAYTTYGAYAAY ATHTGYAAYCAYATHCCNAARTCNYTNGARTAYCARYTNYTNTCNAGYTAYTCNGARYTN ACNGTNGAYGTNCARGTNGTNCCNMGNGARTGGCARACNGCNGCNATGAARGARGCNTAY YTNMGNMGNYTNACNGARGTNCARAGYGAYGARGARCCNGARAARGGNAARMGNYTNYTN TCNAARGGNACNGGNGGNYTNCCNGARATHGTNGARAAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AGYTCNAAYGCNAGYAGYTGYGGNMGNYTNTCNCCN ATHCAYGCNGTNGCNGARCCNGAYYTNCAYGAYAAYCARGTNCCNCCNATGTCNCCNCAY ATGTGGCCNACNGAYATGAAYCARTCNCCNACNYTNTAYTCNGGNGAYTGYTAYTCNGAY YTNGTNGAYTCNYTNGGNGAYGGNATGAARYTNTCNTCNCCNGAYAGYATG------ATG AAYAAYATHMGNGAYCCNTAYATHTCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGAARAAYYTNTAYYTNGARTCNYTNGCNCAYGAYATGTCNAGYGGNAAYCAR---GCN AAYTTYGCNMGNTTYGTNYTNCCNYTNNNNNNNNNNNNNGCNCARATHGGNGAYNNNGTN AAYCAYYTNNNNGGNAGYNNNGCNAARGCNNNNYTNACNNNNNNNAAYAAYATHNNNGAN GTNGAYGCNGANMGNATHTTYGGNNNNAAYNNNCAYTTYGAYYTNCCNMGNATHAAYTAY GARNNNAAYNNNNNNAARTAYMGNTAYNNNTAYGGNNNNNNNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNAARYTNGAYATHNNNACNAARNNNNNNNNNNNNTGGNNNTGYCCNNNN NNNAAYTAYNNNNNNGARCCNGTNTTYGTNNNNCANCCNNNNNNNACNGANGARGAYGAR GGNGTNGTNYTNTGYCCNNNNGTNTCNNNNNNNTCNGANNNNCANTCNTTYYTNGTNATH YTNGAYGCNTCNACNTTYCARGARYTNGCNACNGCNTCNATHCCNGTNGAYNNNAARATG AAYNNNNNNTTYCAYGGNACNTTY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------CCNCCNCCNATHGGNCCNCARCCNGARTAYGTNAARACNMGN AAYGGNYTNTTYAARATHGCNGARGTNATHYTNTGYATHYTNGTNYTNATHTGYTCNTCN TCNGTNTAYTGGGCNCAYYTNGGNGGNGGNTGGGTNCARTTYGTNGCNGCNTCNGGNTTY YTNACNACNGCNATHYTNTTYYTNYTNTTYTTYYTNAAYATHGTNCCNMGNATHCCNGGN TCNTGGACNYTNATHGARTTYATGTAYTAYTGYATHTAYTGYYTNATGTTYATHATHGCN GCNATHGTNTGYTCNGTNMGNGCNCAYYTNCAYGAYGCNATHGCNGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CCNCAY YTNCARGGNGCNGGNAAYGAYAARGARGAYGGNGTNGGNTCNTCNGGNATHTTYATHTAY ACNCCNYTNTCNYTNTCNAGYTCNAARGCNGAYGAYAGYMGNCCNGAYTTYAARTGGGTN TGYGGNGAYGTNTGYGARGCNACNYTNCARGTNTCNAAYCCNYTNGTNGAYGARYTNGAR GTNTCNCARATGGCNYTNATHACNTCNGAYYTNGAYGCNGARGTNTTYCCNGGNTGYCCN ACNATHCCNCCNTCNTCNAARTCNTCNACNATHAARYTNAARGTNATHCCNAARGARGCN GGNAAYYTNAARGTNCARGGNTAYTCNACNGTNGTNTTYGGNGTNAARAAYAAYTGYMGN YTNMGNGAYYTNACNAAYYTNMGNCCNTCNCCNYTNACNGARATHTCNATHCARGTNATH CCNTGYYTNCCNCARATHACNGTNTCNTGYTCNYTNCCNAARTCNCCNGTNTCNGCNTCN ACN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TGYGARATHTGYGCNGTNACNAARTCNGAR TTYGCNAGYTAYACNTGYTGYCAYAARTCNGTNTGYACNGAYTGYAARGTNMGNYTNAAY AARTGYCCNTTYTGYMGNAARATHCARMGNGARATHACNGGNGAYATGCCNGAYGGNTTY ATGGARATHAARMGNMGNGCNACNAAYYTNTGYGGNTTYCCNAAYCCNTCNGGNCAYTTY GARATHAAYTAYTTYTTYAAYGARYTNTCNCAYTCNMGNCCNCAYTGG------------ ---------------------------ACNGCNTAYYTNCCNGAYGARGGNYTNCAYGTN YTNAARYTNYTNYTNGTNGCNTTYMGNMGNMGNYTNACNTTYACNAARGGNACNTCNATH ACNACNGGNAARCCNAAYCARATHACNTGGAAYGGNATHCAYCAYAARACNTCNYTNCAR AARGGNCAYCARTTYGGNTAYCCNGAYGAYACNTAYYTNATGMGNGTNTGYGGNGARYTN AARGARTTYGGNGTNTCNYTNAARGCNATGACNAGYMGNGARATGTCNGARGTNGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGGAYCARCAYTAYGGNGTNGCNGTN ACNAAYAARTTYGCNYTNTTYACNGAYGAYGAYGARGAYCCNATHGARGCNGTNYTNAAR GARGARAARAARTCNAARACNAARAARCCNGTNGARGARGARGAYAARAARGAYAARGCN GTNATHCCNCARAAYGAYGAYACNGARCARAARGARGTNGGNGAYAARCAR--------- ------------------------------------TGGCARACNGARAARGGNAARGGN AGYGCNMGNAAYMGNGARCCNMGNGARYTNMGNGARAAYGAYGGNGAYMGNMGNCCNCCN MGNMGNCARGGN------------------------------------------------ ------CCNMGNGAYTAYAARGAYGGNAARGCNGGNGAYGARAAYGTNCCNCCNGARTTY MGNGARCARCCNCARGGN---GGNTTYAARMGNMGNGARGAYMGN------GARGGNAGY GGNTTYGGNGGNGARMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNMGN---GGNMGNGGN GGNGAYMGNAGYAGYGGNGGNGGNTTYGGNCCNMGN------------------GGNGAY CARAARMGNGARTTYGAYMGNCAYAGYGGNACNGAYMGNACNGGNATHAARGCNATHGAR AARAARGARGGNCAYGGNGCNCAYAAYTGGGGNAGYTTYMGNGAYGAYATHGARGARCAR GGNCARATGAAY---------GCNCCNGARGAY---AGYAAYGARAARGARAGYCARCCN GARAARACNGARCARAGYGARAAYGCNGARGGNGTNAAYGCNGCNGARGARGAYGCNCAR CCNCARCARATGACNYTNGAYGARTGGAARGCNYTNCAR---GTNCARAAYAARCCNAAR CCNAARTTYAARATHMGNCARGCNGGNGARGGNGTNGAYTCNGCNCARTGGAARCARGGN GTNGARTAYCARAARAARYTNGAYGGNAGYCARGAYCAYGGNGARCAYGAYGARGGNGAY CCNAGYGAYCAYYTNAGYMGNGAY---------AAYAARCARYTNYTNTCNGAYATHMGN ATHACNTTYAAYGAYAAYCCNMGNMGNGGNMGNGGNMGN---MGNGGNGGNMGNGGNGGN ATGGARMGNGGNGGNMGNAGY---------------GGNMGNGGNGGNMGN------GGN GCNCCNMGNGGNTTYGGNAAYAAR---AARGARACNGCNCCNMGNTTY---GAYGARGCN GAYTTYCCNTCNYTNYTNAARACNGCNGCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNAGYGCNYTN GAYYTNGAYACNATGYTNAGYTAYATHTTYGCNTGGATHGARAARCAYAARTCNYTNACN CCNCCNGCNCARGCNTTYYTNATHGTNGAYGGNTTYACNATHTTYAAYCAYMGNCCNYTN TCNAAYYTNTGYGAYAARAARTTYTTYYTNCARGTNGAYMGNGAYACNTCNTAYGAYMGN MGNGGNACNMGNGTNTAYGAYCCNCCNGAYATHCCNGGNTAYTTYTCNGARATHGTNTGG CCNATGTAYYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNCAYGTNMGNCAYAAR---GGNAARCARMGNATHMGNGAYGCNAARGTNCAR GCNGAYAARAAYAARACNTTYTTYTCNAARAARGAYMGNAARCARATHCARTCN---TCN GCNAGYGCNTCNATHGARAARAGYACNATHYTNGCNGAYAARCCNGTNGAYAAYGTNTGG GTNMGNAARTTYTAYCCNACNCCNMGNTTYTCNATHGAYAAYGCNTTYGARMGNCAYCAR GCNTTYGCNCARCCNGCNATGYTNGAYAAYATGGARGGNYTNGTNTAYYTNGAYATGYTN YTNGAYTTYACNACNAARAARAARACNAARTTYYTNAARAAYATHMGNTCNACNGTNYTN YTNCCNCAYCCNTTYAAYTGGGGNCCNCCNCCNAAYATHYTNGTNTTYTGYAARGARGAR GARCAYACNACNYTNGCNATGACNYTNGGNGCNAARCAYGCNGGNTCNCCNCCNGARGTN ATHAARATGATHGARACNGGNATHYTNAAYCCNAARGAYTTYACNCAYGTNYTNGCNACN GCNGAYTGYGCNGCNGAYATHACNCCNGCNMGNTCNTAYTTYMGNGAYAARTTYCCNCAR MGNGCNAARMGNAGYYTNGGNACNGAYYTNAAYGCNATGTGGACNYTNTTYTAYGAYGGN TAYACNTAYGARACNCARAGYYTNTCNGARTCNCARGGNAARYTNCARGTNCCNGTNGGN CARYTNAARCARCCNACNAGYCARYTNGTNGCNAAYTTYGARGCNTTYGTNGARTCNATH TGYAARCAYMGNAGYATHGCNYTNGGNCCNTTYATHCARTCNATHAGYGTNGTNGCNCCN CCNTCNCCNGARGARTTYYTNGTNAARGTNGARGAYTAYGTNCCNGGNTAYCARAAYGAR GARGTNGAYTCNGAYGAYGARGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CCNGTNYTNGGNCARTTYTCNAGYATHGGNTCN YTNGGNGCNAAYCARGAYGCNTGGYTNYTNAGYGARTGGGGNCARTCNGTNTCNACNTGY MGNAARTCNYTNCCNTCNTCNATHCCNGCNTCNAARYTNAAYYTNATGTTYCCNTCNAAR GAYAAYATHMGNYTNAGYYTNGARGGNTAYAAYGGNGGNGGNTGYGTNCCNTAYTCNATH AARACNGCNTCNAARCARCCNTGGYTNACNCCNTTYTTYTGYCARTGGMGNTCNGARGGN MGNGGNMGNTCNMGNGCNGTNCCNCAYATHAARTCNTAYACNMGNTCNTCNCCNGAYGGN TCNCARGCNGCNTGGTTYATGGTNACNAGYGCNAAYYTNTCNAARGCNGCNTGGGGNGCN TCNGARAARAARGGNAGYCARYTNATGATHMGNTCNTAYGARATGGGNGTNYTNTTYYTN CCNGARGAYTTYGGNTTYAARAAYTCNTTYAARGTNAGYAGYCAYATHGAYCARTTYACN GAYCCNGARGTNAARGTNTTYCCNYTNCCNTAYGAYYTNCCNACNACNACNTAYGTNAAR GGN---AARAARTCNATHGARYTNTTYTAYGAYGTNGTNTCNCCNTAYTCNTGGTTYGCN TTYGARGTNATGGCNMGNTAYCAYCAYMGNTGGAAYATHAGYYTNAARYTNMGNCCNTTY TTYYTNGGNGGNATHATGCARGCNTCNGGNAAYMGNCCNCCNGCNATGGTNCCNAAYAAR GGNYTNTAYGCNATGGTNGAYGTNGARMGNTGYGCNMGNTAYTTYGAYGTNCCNYTNGTN GTNCCNAARAAYCCNGCNGARYTNATGTTYGARAARGGNTCNYTNAARGCNCARMGNTTY YTNACNGCNGTNGAYYTNAARTGYCCNGARAARGTNGARGCNGTNTCNMGNGARTTYTGG ATGMGNGGNTGGTCNMGNGAYGARGAYYTNTCNGARGAYTCNAGYYTNGCNGARGCNGCN ACNAARGCNGGNYTNAGYCARCARGARATHCARGARTAYYTNGGNMGNYTNAARGAYCAR GAYGTNAARGAYMGNYTNAARAARAAYACNGAYGARGCNATGGARYTNGGNGCNTTYGGN TCNCCNATGATHGTNGCNAAYATHAAYGGNAARAARGARTGGGTNTTYGGNAGYGAYMGN TTYCCNATHTTYGCNCARATGATHGGNAARATHCAYTTYGGNYTNTGGCARYTNTGYTAY ACNAGYCCNGTNAARGARGAYTGYAARATGTGGTTYCARGAYATHGARGGNCAYTCNYTN GAYCCNGGNGTN---------------TGGATGMGNGGNGCNCARAGYATGGCNACNYTN GGNGCNATHATHYTNGGNAARTGYGCNGTNGGNACNATHYTNAAYYTNGTNGTNGARAGY MGNGGNGAYMGNAARMGNYTNYTNCCNTTYATHATHTGYGGNTTYTGYTTYGCNGGNGGN TTYTTYGTNTTYGTNGGNGARATGATHATGGCNACNAAYCAYAARTCNGCNACNAAYATG CCNAAYGAYCARCCNYTNACNGARGGNGTNAARGAYGTNYTNMGNGAYGARTTYTCNYTN GGNTGGGGNTTYGAYYTNGAYATHYTNCCNGTNATHATGTCNTGYATHTGYGGNGTNYTN CAYYTNGTNGCNMGNMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CAYAARYTNAGYMGNYTNYTNCAYAAY ATGYTNGTNACNTAYYTNYTNTCNGARGCNCAYTCNGGNYTNGAYYTNCCNTGGTCNATG CAYMGNATHYTNCCNAAY---ATHTAYGGNGGNGCNTAYMGNCAYGARTTYCAYCAYCAR MGNMGNGAYTGYTGYTTYCAYCARTTYTTYTGYTAYYTNGAY------------------ CCNGCNAGYCCNTAYAAYCCNTAYATHACNACNTCNGTNCCNTCNCAYTCNGTNGCNATG ACNACNAAYGGNGAYGCNAAYTCNCCNATHATHTCNCARGCNYTNCCNCAYACNATGATH CCNGCNGCNCCNAARGCNGTNMGNGCNGAYAARTTYGARACNGTNCARGARAAYGGNGAY TGYYTNACNAGYACNACNCAYYTNYTNGAYCCNYTNAGYTTYCCNACNTAYTTYACNCAR CARAGYTCNGTNCCNGGNATHATHCCNGCNTAYAARMGNATHGCNGTNGGNGAY---GCN TCNAARGGNGGNATHCCNYTNTAYCCNGCNAAYCAYYTNATGTCNCCNTAYCARCARCAR GCNGCNTCNYTNGTNCCNYTNCARCARCAYCCNTCNTAYATHCCNATGCCNTAYCAYYTN CCNTAYACNCARCCNYTNGCNGGNCAYCCNCCNAGYGTNCCNMGNTTY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARAGYAGYGAYGARGARYTNCCNGAYATHCCNTTYAARATHCCNGARCAR AGYAARACNAARAAYGCNAGYTTYTGYAARTCNCCNCCNYTNCARATHCARTGYGCNATH TGYYTNGAYGAYYTNAARCARATHAARTCNAGYAARAARMGNGTNATGTCNACNATHTGY GGNCAYATHTTYTGYGARGARTGYATHGTNAAYGCNATHAARACNTAYMGNTCNTGY--- ------------------------------------------------TCNGCNTCNTCN TCNYTNAARGTNTCNGAYCCNGAYTCNGAYGTNACNATGTCNCCNMGNGARGGNTAYAAR ATHAARMGNCARAAYMGNAGYAARACNYTNCCNATGGGNAGYTCNGARGARGAYAGYCCN AGY---AARATHCARMGNGCNAGYTCNCAYMGN---ACNCCNGCN--------------- ------------------AAYACNGCNTCNGARTCNTCNACNGTNAARAARYTNGGNGCN ACNMGNTTYAGYCARTTYGARTCNAAYAGYTCNTCNGARCCNTCNTGGATGAAYAARGTN AARCARAARAARYTNGARAGYAGYGARGARCARGAYCARAARAARGCNTCNCCNGARGAY GGNGTNMGNMGNGGNAGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CAYGTNAARACNCAYYTNCAYTCNTCNCAR AARAARATHTAYYTNTGYGARGTNTCNAAYTGYGGNCARAGYTAYACNMGNTCNGAYGCN YTNGCNMGNCAYCARATGAAYTCNCAYGGNATHAARGTNAARCCNTCNAARTGGMGNCCN ---ATHTCNTGYAARYTNCARATHAARCCNTTYGARATHACNAARGARAARGAYCARMGN CARATHATHYTNCARGGNCCNYTNGGNGTNGGNMGNGCNYTNACNCCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYGAYTCNMGNCCNGCNTTYCCNMGNCCNCCNAAYTGY ATHGGNYTNTAYYTNGAYGCNYTNGAYGCNMGNCCNGAYAARGGNACNGTNGTNGGNTCN CAYCAYGCNTTYATGATGAAYGTNATGGAYMGNYTNCARGARTAYYTNMGNGAYYTNGAY YTNACNAARYTNAARGGNGGNATGGARTCNMGNCAYGTNGGNAAYGGNGTNATHYTNGAR GGNGTNAARCAYAGYTGYATHATHGCNYTNACNTTYGAYAGYCCNGARGCNYTNGAYGGN TTYTGYCARYTNCAYMGNMGNAAYMGNYTNACNCCNGTNTTYCARGAYATHYTNGTNGAY AARGTNYTNYTNAARTTYACNAAYTGYGCNAARYTNACNYTNMGNGTNAARATHTGGGAR GAYGARGTNAARGGNTGYAARGARGAYYTNGTNAARMGNCCNGAYACNMGNATHYTNYTN TCNAGYTCNGARMGNGAYTTYGCNYTNGTNMGNMGNGTNCARGARTAYCARAARYTNATG CCNCCNAARGTNGCNAARTCNMGNGAYGCNGARAGYMGNTTYGARCAYAARYTNGGNGAR TTYATGYTNACNATHAARCARATHYTNCCNCARAAYACNCARGTNATHAARACNATHAAR GARTTYYTNACNAAYGTNAARATGGCNMGNGGNGTNAARAARGTNAAYTAYGAYAAYATH GAYCAYTAYYTNCARTCNYTNGARTTYTTYMGNAARACNTTYCARGARATHGARMGNCAR ATHGTNCAYCCNYTNTGYCARATHCARGCNATHTGYGARAAYGARAARCARCARAAYYTN AARAARACNATHAARAARGCNACNTCNGARATGYTNGGNTAYYTNAARCCNGAYGTNGAY YTNCARAARGTNMGNCAYAARGARTGGGARGGNAARGTNYTNYTNMGNGARCARGGNYTN TTYTCNGGNYTNATHAGYYTNATHCCNATGAGYGTNGAYMGNYTNACNACNATHGAYTAY AGYACNGAYGARTAYATHAAYGAYTTYCCNGARATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GAYTTYTGYAAR MGNATHTCNGARMGNGARCARGARAARGTNGAYAAYGAYATHAGYGAYAGYAGYGARGAR GAR---GCNCAYACNGAYGARGARGARCCNYTNATHCAYCAYCCNTTYAARGTNAARGAY ---ACNTCNAAYATHGTNATGAAYATHMGNAAYGCNAARCARYTNCCNGTNYTNACNCCN TCNGARAARCARGCNCARCARGCNTCNYTNMGNYTNGCNTTYCCNGTNTCNAGYGGNTCN CAYCAYMGNGCNAAYGARTCNGARTGGGTNCCNGTNGARAARACNACNGCNCARTCNACN TCNACNATHAGYMGNGCNGTNGAYTCNACNAGYAARACNGAYTCNCARCCNGTN------ ---------AAYAARGAYAGYATHTTYAAYACNAAYTCNGCNAAYGTNGAYATHGGNGCN ATHATHTCNGARMGNYTNCARGCNGTNMGNAARYTNCARACNAAYCCNTAYGAYGTNCAR GCNYTNAGYTCNATGCAYAARGCNCARGARAARGCNAGYCARTGGGCNCARTCNAARCAY YTNCCNGGNCARTTYATHGGNAGYACNGGNGCNCAYGTNATGTCNCARGARGARATHATG GGNGAYAARMGNMGNCARGCNTGGGTNAARAARACNCARTTYAGYACNGCNACNCCNGTN AGYGGNGGNATHGGNATGTTYYTNYTNCARAARATGGGNTGGAARCARGGNGARGGNYTN GGNAARAAYAAYGARGGNACNACNCARCCNYTNCARYTNGAYATHAARATHGAYMGNAAR GGNYTNCARAGYGCNGCNGAYAAYCCNAARTCNAARCCNCARATHGCNCAYGTNCCNCAR GCNAARGAYYTNTCNCAY------------------AARCAYCCNGTNTCNGCNYTNATG GARYTNTGYAAYAARMGNMGNTGGGGNCCNCCNAAYTTYACNGTNGTNCARGARGAYGGN CCNGCNCAYAARAARTGYTTYYTNTTYAARGTNGTNAAYATHACNGTNAARGARAARGGN ACNGCNGTNYTNCCNTGYTCNGTNATHAAYYTNGGNAAYTAYCARTCNGTNTGGACNGAY CARTAYCARACNATHYTNACNTAYGGNGAYMGNMGNGTNATHGAYGAYGAYMGNGTNAGY GTNGARMGNCCNTAYCCNMGNGARMGNAAYYTNCAYATHMGNGAYGTNMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNAARCARTTYCCNAARATGGCNGAYACNCCNGAYYTNATGAARACN TTYMGNACNTCNTGGCAYGARAARYTNAARGARGTNMGNMGNGCNGARAARMGNGAYGAR GARTAYATGAARGARACNTTYMGNCARGTNTTYATGGAYTCNACNTAYCCNATHCAYCAY GTNGCNACNYTNCCNCCNTAYMGNATGGGNGAYGARGAYAAYGAYAARGTNMGNCARGAR AAYATHAGYMGNTAYAAYGARACNAARMGNGGNAAYAARAGYGCNYTNGCNGCNYTNYTN TCNCCNAAYYTNGTNTTYCAYCCNATGATHYTNGAYGARGTNACNTAYAGYYTNATHGGN CCNAAYTGYYTNAAYAARCCN---------YTNGTNGTNCARGCNGARGARYTNGGNTGY GARGGNAARGTNGARGARGCNCARGGNGTNATGAARYTNGTNGAYCARYTNAARGARGAR MGNCAYCARYTNGAR------ACNAARGCNATGCARGAYGAYGGNGGNCCNYTNATGAAR CARATGGARGTNTGYGAYGTNTGYGGNGCNTTYYTNATHGTNGGNGAYGCNCCNCARMGN CARGAYGARCAYYTNATGGGNAARCARCAYGCNGGNTAYGCNCARGTNMGNGCNGARATH GAYMGNMGNAARAARMGNGTNMGNGAYGARACNGARGCNMGNGARGCNAAYGARACNMGN YTNMGNYTNGARMGNGARGARMGNGARAARGARMGNCARMGNGARMGNGARGARMGNMGN CARMGNGARMGNGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GAYACNYTNATHGTNCAYTGYCCNAARGGNTTYATHGAYTTYATHTCNAGYCAYTTY AAYGGNMGNMGNGGNAARAAYTGGGARGAYYTNYTNAGYYTNTAYGGNTGGAAYTAYAAR GAYATHAARYTNTTYGGNAAYAARAAYCAYYTNGAYGGNTAYTTYMGNGGNATHYTNGAR GARGARGGNTTYCARGARTAYACNATHGGNYTNYTNAARGAYGAYYTNAAYAAYATHCCN AARAARGAYACNYTNAAYGAYGTNATHAARTGGATHGARGAYTAYAAYATGGAYTTYGAY TCNTCNTCNAARTTYATHGCNTCNYTNGCNMGNTTYYTNCARTCNYTNTGYAAYGGNTAY GTNGARTTYGAYAARGGNGTNGARGTNATHGGNCAYATHTAYYTNAGYGTNGAYAGYGAY ACNGGNMGNAARATHGAYTAYGTNYTNAAYGARAARGTNTGYAARAAYGAYAAYTCNGTN ACNTTYATHAGYAAYAGYTTYCAYGCNCARCCNGCNGARAARCCNCARCCNCCNAARAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ MGNAARCCNYTNTCNTCNCCNAAYGGNCARTGGACNACNCCNTCNTTYTAYATGGGNGAY GTNATHATHTCNTCNACNCARCARYTNGARGAYACNTTYYTNGAYCCNMGNCCNTTYACN AARGGNCARGCNTTYATHAAYAAYTTYAAYYTNGGNMGNTAYTGGCCNAAYMGNGGNCCN CARGTNMGNYTNTAYGTNCCNAARCCNGTNTTYAAYGGNCCNGCNGCNACNAAYMGNYTN TAYYTNTTYGARYTNGARAGYTCNCCNTGYCAYAAYTCNTCNGAYTGYAARGTNTCNYTN GTNGAYACNCCNTAYYTNGAYMGNCCNAAYGGNCCNGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNGGNAAYCARYTNGTNGARTGYCARGARTGYCAYAGYYTNTAYCAYCARGAR TGYCAYAARCCNACNGTNACNGARCARGAYGTNAGYGAYCCNMGNTTYGTNTGGTAYTGY TCNMGNTGYACNAARAGYTTYAARAARATGATGGCNCARAARCCNATHAAR---CCN--- AGYAARCCNGTNCCNYTNACNTCNACNTCNAARGARCCNACNTCNACNATHATHAARACN AGYAARTCNGARTCNGAYTCNGCNAGYCARGCNTTYMGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNATHCARATHAARACN ACNGAYGARAARGARGTNCARMGNMGNATHGAYGCNTTYATHMGNAAYAARMGNAAYGAR GTNAAYGARMGNAAYATHMGNGARTTYATHTCNCCNTTYGGNTCNGAYCCNAAYAAYAGY TGYGCNMGNGTNGARGCNGTNTAYTTYCAYMGNGARGGNATGAARAGYCAYATHAAYYTN AARAAYGTNGARAAYTCNTAYGGNCCNCARACNMGNYTNMGNCCNGAYGAYAARGARGGN MGNCARTCNTGGATGATGTCNGCNGAYGCNCARMGNGCNGARGCNGTNGAYGARMGNYTN TCNAAYATGGARCAYCAYYTNAAYATHGTNAAYGAYGGNAAYGAYATHTAYATGMGNATH AARGCNYTNGARAARMGNATHAGYTTYYTNGARGGNGTNTCNCCNGARTAYTTYTCNAAY GGNATHCCNCCNCCNAARAAYMGNAAR------------------------------YTN GTNCCNACNAARCARACNACNGCNGARATHGCNAGYCAYCCNACNGAYATHGTNGTNAAY AARTTYGARGAYCAYYTNTTYATHATHGTNACNCARTAYCARAARYTNGGNACNGTNGTN GARGTNTCNMGNGAYGTNGTNAGYGAYGARGTNCARGGNCCNATHCCNATGTTYTCNACN AAYGTNYTNYTNGGNAARGAYGARCCNYTNACNCAYGTNATHGCNAARACNATHGTNACN GCNYTNAAYCCNCCNATHCCNGTNATHYTNAGYGTNGCNYTNAARGARACNTCNCAYGAY GCNGTNYTNTCNATHATHGARYTNATHAARACNTGYYTNATGGCNACNAAYATHCAYTTY GARGCNMGNMGNMGNCARATGGTNYTNGAYAARGCNAGYMGNGCNMGNAARGARATG--- ---AGYYTNGGNAARAARCARGAYGCNGTNGCNACNGCNGAYGAYCARYTNAARCCNGAR ACNATHGTNTGYACNGAYCARGGNCARTTYTAYCARACNMGN---AGYATHCAYGTNTGG ACNGGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGCCNAAR TTYTAYGARGAYGTNGARGAYAARCCNACNMGNACNAARYTNGCNTGYGARGGNATHMGN GAYGAYYTNYTNGARTGYYTNYTNAARAGYGAYTGYTGYMGNAARGAYAARAAYACNCCN MGNCARTGYATG---------TCNAARGTNGGNGAYCCNTCNGTNCCNGAYGARTGYCAY AARYTNMGNGTNGCNTTYTTYGAYTGYMGNMGNTCNATGYTNGAYATGMGNACNMGNTTY MGNGGNMGNAARGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARGARTCNGAYTCNGGN---GGNYTNTCNACNGGNTCN GCNGCNGCNATHGGNTTYYTNGTNATHGTNTGYGTNGTNGGNYTNATHYTNGGNATHGTN GTNTTYTAYMGNMGNAGYAAYATGACNAGYMGNAGYYTNAARGCNTTYYTNACNGGNGGN GTNMGNTAYAARACNTAYACNAAYGCN--------------------------------- GARGAYAARTCNMGNAARAAYGCNATHCARGCNAARATHAAYMGNGARAARAARAARGCN TAYATHAARAGYYTNGARGAYGARATHTCNACNYTNMGNAGYGGNAAYGCNAARYTNACN TCNGARAAYAARATHATGCARAGYAAYATGTCNGARYTNGARGARGARGTNGARTAYYTN AARTCNGTNYTNGTNAAYTCNAGYTCNYTNTCNAGYYTNYTNAARAAYATHTCNAAYGTN AAYGARGTNAARYTNTCNGCNACNYTNATHGGNAARAARMGNTCNGTNAGY------GAY GAYCAYAGYTAY---------GARTCNGTNCCNCARAARMGNGCNMGNMGNATHAAYGAR AAYYTNAARAARGCNGGNGTNTGYYTNCAYGTNAAYGGNGGNTCNGCNAGYYTNGARTTY TGYGCNCAYTGYTCNAARYTNGCNCAYAARTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY GARCAYGGNYTNGTNAAYCAYATHCAYYTNATGTGYGAYMGNCAYYTNGAYCARYTNATH ATGTGYTCNYTNTAYYTNATHGCNAARGTNACNGAYAARACNYTNACNTTYCARAAYATH ATGAARTGYTAYMGNYTNCARCCNCARGCNCARAGYCAYGTNTAYMGNAGYGTNYTNYTN CARGAYMGNYTNMGNCAYAGYTCNGGNAGYAGYGAYAGYAGYAARAGYAAYAGYAGYACN YTNCCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TTYGGNGGNGTNGGNGCNYTNTCN GGNGTNAARAAYCCNGTNAAYGTNGCNAAYYTNYTNGTNAARGARCARATGGARGGNCCN YTNCCNTTYGGNMGNGTNMGNCCNAGYATHYTNGTNGGNAARGGNGCNAARACNTTYTGY ATGAAYCAYGGNATHGAYACNAAYTAYAAYATHATHTCNAARTCNGCNTTYAARACNTAY AAYMGNTAYAARMGNAARTGY--------------------------------------- ---ATHTCNGAYTCNAAYAAY---GCNAARMGNMGNAARGTN------------------ ------------------------GARCCNGTNGAYGARAAYCARACNTCNGARYTNATH ---ATHCARGAYACNGTNGGNGCNATHTGYGTNGAYCARGAYGGNAAYGTNGCNGCNGCN TCNTCNAGYGGNGGNATHTGGYTNAARCAYCCNGGNMGNYTNGGNCCNATHTCNATGTAY GGNGCNGGNTGYTGGGCNCARAAYMGNGCNTCNGAYGAYAARCCNGGNGTNGCNGTNGTN ACNTCNGGNTGYGGNGARCAYATHATGCARACNGTNYTNGCNAARACN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGGAY ATGGARGARYTNAARTCNATHTAYTAYGGNYTNGAYATHYTNAAYGARCCNGTNACNATH AAYCARGARACNTCNGGNGGNTCNGTNCARGTNACNTCNAARTAYGGNCARCARTAYCAR TGYACNTTYCCNGAYCAYTCNGARYTNGARAARAARAARGARGARGARGARAARGTNGCN GTNGARACNGGNATHGTNGARATGYTNAARTCNATGAARACNCARGAYTGYYTN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GGNACN MGNGTNGGNAARGGNTGYACNAGYGGNCAYGGNATHTGYGGNYTNCCNMGNTTYTCNTCN MGNAGYTGGGTNGCNGTNCCNACNTTYATGGGNTGYGCNATHGTNACNGTNGCNYTNACN MGNCAYGGNTTYCARTGGGAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARATGTAYGTNGCNGTNYTNMGNACNCARAARAGYGTNYTNCARGAYAAYGCN GAYAARATHTCNGAYGARATGGARGARGTNTGYMGNYTNYTNAAYGARGARAARCARAAY CAYGAYTCNYTNAARCARACNTGGCARATGGCNAAYGAYCARTTYYTNGARTCNCARMGN YTNYTNATGATGGAYYTNMGNMGNATGGARGGNGTNYTNTCNACNGARCARCARMGNCAR ATHGCNGARYTNCARCARAARGAYGARCARMGNGAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNGARTAYMGNGGNMGNGGN---MGNAGY GGNGGNTGGMGNGGNGGNCCNCCNMGN---GGNGGNTTYMGNGGNGGNMGNGGNGGNTAY ATGATHGAYMGNGARGGNGGNMGNGGNGGNGGNTTYMGNGGNMGNGGNGGNTTYTCNMGN GGNMGNGGNGGNCCNCCNMGNAGYMGNGAYGAYATGTCNCCNCCNMGN------ATGTCN MGNAGYTAYGAYACNACNGAYMGNGGNMGNGGNCCNCCNTCNAGYMGNMGNCCNGAYMGN TAYGAYGAYAGYTTYGAYMGNGGN------CCNACNMGNGTNAARGAYATGTAYTCNTCN CCNCCNMGNGAYTCNGGNMGNAGYTTYGAYMGNCAYTCNCCNCCNCAYMGN------MGN GAYMGNGAYTAYCCNCCN---MGNCAYAGYGAYCAYATGAGYTCNMGN---GAYTAYYTN TCNCCNMGNAGYTAYAGYCCNCCNMGNGAYTCNGGNTAY---AGYTCNTAYAARGAYTCN TAYAGYTCNGGNCCNMGNGARGAYMGNMGNAGYAAYMGNGAYTAYCCNCCNCCNMGNAGY GGNGGNGAYTAYGAYAGYCAYMGNGGNAGYGGNMGNGAYTTYMGNGAYGGNCCNMGNAGY GAYTAY------AGYACNMGNGAYTAYCCNCCNACNTCNTCNMGNAAYGGNGAYTTYMGN GAYTCNATGAGYAGYMGNGAYTTYMGNGAYGCNCCN---------MGNGGNGGNGAYMGN TAYGGNAGYGGNGGNMGNGGNGGNAGYAGYMGNGGNGGNAGYAGY--------------- ------------MGNGGNMGNTCNMGNTTY------------GAYGAYAGYMGNGGNCCN CCNTCNMGNGAYTAYAGYTCNMGNGGN---------------MGNGGNGAYMGNGAYGAY GAYMGNGGNAGYMGN------GGNTTYATGAAYGGNGGNTCNMGNGGNTCNMGNGGNGGN CCNMGNGGNMGNGGNMGNGAYTTYTCNGGNAGYMGNGGNGAYMGNMGNTCNCCNAGYMGN GARGGNGCNGGNGGNAARMGNCCNMGNYTNGAYTCNGGNGAYTAYMGNMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GAYATHAGY TTYAAYYTNAGYAGYYTNGAYATGTCNGCNAGYAARGTNCARCAYATHTTYACNMGNATG GGNYTNACNYTNAARTCNYTNATGTCNGCNACNMGNGCNACNCCNGCNTAYMGNYTNGCN AARAAYCARGGNGARAARGGNGGNGGNTAYAARYTNAAYTAYMGNTTYTAYYTNGGNCCN CCNAARACNCAYATGYTNGGNGARGAYTTYAARACNGTNAARGCNGGNGCNGTNCCNTCN GCNTAYGGNYTNYTNAGYGTNGGNGTNTCNTAYMGNACNAARYTNYTNYTNTCNCCNGAY ACNACNGCNTCNTCNTCNAGYATHATGCARGTNACNGAYGAYTAYTTYGTNAARGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNGTNCCNYTN GCNACNTCNATHCARATGATGAARAAYATHATGTCNGCNTTYGTNMGNAARYTNGTNTCN YTNYTNGARGARMGNAGYATHYTNCARAAYGCNGARYTNTCNAARAAYGGNYTNGARTGY GTNAARMGNTTYTGGTCNYTNTGYTCNMGNCARCARAAYGTNGTNTCNTCNTCNCARYTN TTYGGNAARTGGCAYCCNAARYTNATHGARGARGTNACNCCNYTNGCNTCNGTNTTYATH GAYYTNTTYYTNTCNGCNCAYGGNCARAGY------GARAARGCNTCNCAYMGNTCNAAR CARYTNTAYAGYTGGYTNAAYTTYGAYYTNCCNGAYMGNGCNATHAARATHGCNYTNYTN GARGCNGARTGYCAYGGNAARGARGGNGTNGARYTNGTNGARCCNATHYTNAGYCARGTN YTNAGYCARCARTCNACNGAYTGGTCNAAYGCNGAYTAYYTNYTNCAYTTYYTNYTNYTN AARAARTGGCARMGNYTNGCNGCN---GTNTCNGAYYTNATHGARGTNTCNAARYTNATH AARGCNCCNCCNYTNTTYYTNCCNTGGYTNMGNACNTAYTGGAARAAYGCNAAYGAYTAY ATHGCNGARGAYAARAAYATHAARGGNGCNTCNGTNAGYCARTTYYTNYTNGAYYTNAAY ACNGAYGAYGTNYTNGAYYTNATHGAYGTNYTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNCCNATGCCNAARCCNCCNCCNTTYAAYAAYYTNAGYTCNACNTTYCCN GCNGGNCCNATHTTYCCNGAYTCNACNAARCARATHCARYTNAGYGTNCCNACNGTNACN TCNCAYGAYGGNAARTTYCARYTNACNATGCCNATHGAYGAYTTYAARCCNGARGARYTN ACNGTNAARACNCARGAYAGYAARGTNATHATHTGYGCNAARMGNGARGTNGTNAGYGGN AGYMGNAAYCAYACNATGGARATGAAYMGNGARCAYAGYYTNCCNGAYAAYGTNGAYCCN YTNACNGTNAARGCNTTYTTYACNGAYACNAAYATGYTNATHGTNGARGCNCCNYTNATG MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARTTYACNGAYGAYGARATH MGNCARGARYTNGCNCARYTNGGNTAYCAYAAYGTNCCNCARGAYAARYTNGARGARTTY AARAARGAYYTNATGGCNYTNATHTCNGARGARMGNAGYAARTCNAAYTCNYTNAAYAGY AGYMGNACNACNGAYCCNGGNGGNAARACNTCNCARMGNATHYTNCARAARCARCARACN AAYACNGGNTAYYTNGGNGAYGAYATHTCNAAYAAYGGNCAYCAYTGGGCN---GGNTCN MGNTTYAAYGARGAYTGGMGNTAYCARGGN------------------------------ ------------------------------------------------------GARMGN GGNYTNGGNCCNMGNCCNCARACNGCNCCNGGNGARMGNGGNMGNAGYGTNYTNAAYATG GAYTTYGAY------------GARMGNAAYCARAGYTGYAAYCAYGAYGAYGTNTCNGAR ACNAGYTCNGARACNMGNTTYYTNAARMGNAARACNTCNMGNAARACNCCNAAYGGNTGY CARYTNATHGAYGARTCNTTYACNGAYACNGARTCNGGNGTNTTYGARATHTAYGARAAR ATHAARAAYYTNGCNATGMGNGARTGYGARTGYGGNAARACNMGNGCNAARTCNGGNGAY GTNGARCCNCCNTAYMGNATHAARGGNAARGTNAAYMGNTAYCCNTCNGTNATHMGNAAR ATGGARCCNCCNCAYACNMGNAAYYTNGTNAARACNGAYGTNAAYGARMGNCAYAARATG TAYAARGARGCNTGGAARACNCARCCNCCNATHGGNGARGAYCAYMGNATHTCNYTNMGN AARCAYATGCAYTCNAARYTNATGAARCARGARGARATHAARGCNMGNCCNAARGTNTAY ATHCCNAAYATGTAYGTNCCNCCNCAYGARAARYTNMGNAARGAYGTNMGNTGGAARGTN MGNCAYGCNTTYGARAARTTYGARYTNCCNCCNCAYGGNTTYTAYCAYGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNAARACNGCNYTNGTNAGYGTNTTY GGNGTNCCNYTNTAYTAYGCNTCNAAYTCNCCNMGNACNYTNATHCARCCNAAYGTNCAY CCNGGNGARTGYTGGGCNTTYAARGGNAAYTCNGGNTTYGTNGTNATHCARYTNTCNCAR CCNATHCARCCNACNGGNTTYACNYTNGARCAYATHCCNAARAGYYTNTCNCCNTCNGGN AAYATHGAYAGYGCNCCNAARTCNTTYACNATHYTNGGNYTNGCNTCNGARGAYGAYYTN GARGGNATHAGYYTNGGNAAYTTYACNTAYYTNGAYAAYGGNAARCCNATHCARCAYTTY ------------------------------------------------------------ ------------------------------------------------------------ ---GARTAYCARTGYCCNTCNCAYYTNTCNCARMGNYTNTCNCARYTNGTNATHGTNGAY AARCARATHAAYAARTCNGAYTAYCAYYTNCCNYTNGGNAAYTCNGTNATHACNTCNYTN ATHGAYCCNCARMGNCAYAAY------GARGARATHAARGAYCCNGCNTCNCARTCN--- ---------ACNCARGTNAARGARGCNAARGARATHATGAARATHMGNCAYAARAARATG AARAARCAYAARYTNAARAARYTNMGNAARMGNATGTAYTTYYTNTGGMGNAARCARAAR ATGGCNMGNMGNGCNAARMGNGAYGCNATHTAYTGGAARGARATHGARGARATHAARAAR GARGGNAAYGAYTTYGAYGCNGARACNTTYGTNAARGGNCARYTNGARAARGCNMGNMGN GGNGGNTAYTAYATHAAYGTNTTYGAYTCNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARYTNAARACNCARATHATHACN GTNYTNAARTTYGTNGTNYTNCARTTYGTNATHAGYTTYATGTAYCAYTTYATHGCNGTN YTNTTYGGNGCNCCNGTNYTNACNYTNGTNTCNGARACNTAYCAYTTYGCNYTNYTNATG ACNGTNYTNACNTGYYTNCCNATGTGYGCNGTNGCNGGNYTNMGNGTNGARAARTGGYTN GAYATH---TTYACNTCNAAYMGNGARCCNGGNYTNCARACNGTNGTNTAYYTNACNACN YTNGGNGCNYTNGTNGGNGCNTGGYTNGGNGCNATHCCNATHCCNYTNGAYTGGGAYMGN CCNTGGCARAAYTGGCCNATHAGYTGYTCNATGGGNTGYGTNTCNGGNTAYTCNYTNGGN YTNTTYATHGCNTCNYTNTAYYTNCCNCAYCARTTYAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHMGN TTYATHTAYMGNAARGTNGCNTAYCCNTCNTGYATGGTNTCNTCNATHGTNACNACNGTN ACNCCNTGGACNGTNAAYTTYTCNACNTTYYTNGCNAARATHGARATGAAYAARGTNACN ACNYTNCARAARGAYYTNGTNAGYMGNCAYYTNGAYAARYTNAGYYTNTAYTAYGGNGCN AGYGAYYTNTGGTGYCCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AGYTTYGCNYTNYTNTCNAARTAYGARTGGATHCAY GGNTTYCARGTNACNGAYATHTTYAARGARGAYGTNATHAGYAARATHCCNCARTCNTGG TAYTCNTGYYTNATHCARYTNTCNGTNGARGARYTNAAYGARATHCCNTTYYTNGGNGAR MGNGGNMGNYTNAARTAYCCNGARTGGCCNGARTCNYTNCARGARTTYYTNCARGARTCN AAYCAYYTNGCNAGYYTNMGNCCNAARGAYGCNGAYATHAARTCNATHGARATHAGYCAY GARATGGCNMGNGGNATHAARAGYAARAARYTNCAYGARGTNTCNMGNATGGCNTCNTTY GTNCAYGARATHGTNACNGARGCNAGYTGYAAYGTNGTNATHGAYATHGGNTCNGGNYTN GGNTAYYTNGAYCAYGTNYTNCAYCARAARTAYGGNATHMGNATHYTNGGNATGGARACN GTNCARAGYCAYGCNTCNGCNGCNGARAARMGNGCNGTNMGNCARGGNATHACNTGYGAY GGNATH------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------YTNTTYTCNGTNAARTAYAGYAAY MGNGTNAARTTYGCNGTNAARMGNGTNTGYMGNCARYTNGAYATHYTNTCNGARYTNTTY TCNAARCARTGYAAYGTNGTNYTNGCNCARMGNATHMGNMGNTCNTAYCARATHYTNYTN YTNTAYMGNAAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNTAYGGNGARCAYYTN YTNAARGARAGYTCNCAYAARAARAARGAYGARGARATHAARAGYTGYTAYAARGARGTN GTNGARGTNAARYTNYTNGTNAARCAYCCNGARAARCARAARTGGGARCARATHGTNGAY GCNGAYGAYTTYAARGTNTGGMGNCAYCARATHCCNAAYTCNCARYTNTTYMGNTAYMGN GTNTTYGGNCAYTTYMGNGAYATHCCNGCNMGNGCNTTYTAYAAYACNCARGTNGAYGTN CAYTAYTGGAARGAYTGGGAYAAYCARACNYTNGAYGTNMGNATHATHGAYMGNGAYACN GAYAGYGGNTCNGARGTNATHCAYTGGYTNTAYAARTTYCCNTAYCCNATGAAYCCNMGN GARTAYGTNTAYGTNMGNMGNTGYTCNATHTAYCCNGARNNNAAYTCNATGATHATHACN GCNMGNGCNACNCARCAYCCNACNTGYCCNAARMGNAARAARACNGTNMGNATHGARACN TAYTCNTCNCARATGGTNATHACNCCNTAYACNTTYTTYGAYGARAAYGGNTTYTCNTAY GTNATGTCNTAYTGYGAYGAYCCNCARACNAAYTTYCCNCCNGTNTGGTAYAAYTGGATG GCNAGYGCNGGNGTNCAYGARTTYYTNGARMGNATGCAYCARGCNGCNYTNMGNAARCAY GARMGNGCNAARGTNGARYTNGCNTCNAAYMGNATGGAYAGYCCNCCNGCNCAYYTNTAY TCNGGNATGGTNCAY--------------------------------------------- ---------------------------------YTNATHTTYTCNCCNYTNGTNGCNACN AARATHGARGGNGAYYTNACNGTNTCNTGGCCNGTNATHTTYTCNCCNYTNTTYATHTGY GAYGGNYTNAAYGCNTAYYTNTGYGTNATHATHTTYGTNMGNCARTAYMGNGARTAYGAR YTNAARCARGCNTGYYTNMGNYTNTCNAAYTCNYTNTCNGTNATHGCNYTNATHTTYACN TTYAARYTNYTNYTNTGYCARAARYTNGARAAYGGNGGNYTNACNTGYTCNGARGTNTTY GCNCCNGTNTTYGTNYTNTCNCARGTNTTYATGTTYMGNGCNTGYMGNATGCAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARATHACNCCNGARATHTCNGTNTCNGARGTNATH ACNGCNAARACNAARATHGCNGCNCCNTCNYTNAARTCNGAYGAYYTNTCN---GARGAY AAYGAYGARAARGARCARTAYGAYYTNGAYATHAARATHACNGARAAYYTNAARATHGGN GAYGGNATGTCNGCNTAYATGGTNTTYAARATHGTNTCNAARACNACNAAYCCNGCNTTY MGNACNCCNGARAAYGCNGTNYTNMGNMGNTTYAGYGAYTTYYTNGGNYTNTAYTCNAAR YTNGCNGARAARCAYGTNCCNYTNGGNATHATHGTNCCNCCNGCNCCNGARAARAGYGTN ATHGGNATGACNAARGTNAARATGTCNAARGARGAYACNGGNTCNATHGAYTTYATHGAR MGNMGNAARGCNGCNYTNGARMGNTAYYTNATHMGNACNGCNGCNCAYCCNGTNYTNGCN GCNGAYMGNGAYTTYATHGARTTYYTNGARAARGAYGGNGAYYTNCCNAARGCNACNAAY ACNTCNGCNYTNAGYGGNGCNGGNGTNATGMGNYTNTTYCAYAARGTNGGNGARTCNTTY GARAARATHACNYTNAARGTNGAYGARAGYGAYGARTGGTTYGARGARAARCAYCARCAR ATHGARGCNYTNGAYCAYCARYTNAARAARYTNCAYTCNAGYYTNGARACNYTNGCNGCN CAYMGNMGNGARYTNTCNGGNAGYACNGCNGTNTTYGCNAARAGYGCNGCNATGYTNGGN AAYGTNGARGARCAYACNGCNYTNTCNMGNGCNYTNTCNCARYTNGCNGARACNGARGAR AARATHGARATHGTNCAYAARGAYCARGCNGARGTNGAYTTYTAYACNATGTCNGARYTN ATGAARGAYTAYGTNGCNYTNATGGGNGCNGTNAARGAYGTNTTYCAYGARMGNATHAAR ACNTAYAARCARTGGAARGAYGCNGARACNACNYTNGGNAARAARMGNGARAAYAARGCN AARYTNGARATGCARGGNAARGCNGAYAARYTNTCNCARGCNMGNACNGARATHACNGAR TGGGARCAYAARGTNGARAARGGNCARGARGAYTTYGARAARATHTCNAARACNATHMGN AARGARGTNGTNMGNTTYGARAARYTNMGNGTNTCNGAYTTYAARACNAAYGTNATHAAR TAYYTNGARGTNYTNATGGARAAYCARGARAARYTNATHAARTAYTGGGARACNTTYYTN CCNGARGCNAARGCNATHGCNGAYGAYGTNCARGARYTNMGNGGNCCNMGNCAYMGNGCN YTNMGNCAYATHAARCCNCARTAYTAYGAYGAYACNACNAGYTAYAAYAGYAGYGAYGAY ATHYTNAAYACNYTNMGNTAYAGYMGNCARGGNCCNYTNACNAARGCNGCNMGNMGNGCN MGNYTNACNTCNTTYAAYGCNMGNYTNCAYAARCARMGNMGNGTNAARGCNGCNYTNMGN YTNAAYAAYYTNCCNMGNACNATGAGYGAYGAYGARTTYTCNTCNGARAAYGAYGAYMGN TAYGARGARTCNAARYTNMGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARTGYCCNTAYGARGGNTGYGGNAARAGYTTYCCNTTYCCNACNGTNYTNMGNMGNCAY ATGAARGTNCAYCARGGNTAYGAYTGYGAYATHGARGGNTGYGGNGARGTNTTYGARACN TAYATHAARYTNMGNAARCAYAARGCNGTNGAYCAYGGNCCNGAYYTNGTNTGYMGNCAR TGYCARGCNGARTTYAARACNMGNCARACNYTNGTNCARCAYYTNAARACNCAYYTNTTY GTNAARGARGTNTTYGGNTGYACNGARACNGGNTGYGAYMGNACNTTYYTNTAYAARAAR AAYYTNAARCARCAYATHMGNGCNTAYCAYYTNGGNGARMGNGTNTTYACNMGNAARAAR ------------------------------------------------------------ ---------------------------------CCNAARGCNCCNATGGAYAAYGARGAR ACNACNTCNAAYAAYCCNGGNAGY---GGNGAYGARGAYMGNCARGTNYTNGCNCCNGCN GARGGNCCNMGNGARGAYYTNATHAAYACNGCNATHAARTTYYTNCARAAYCCNAARGTN ATGGGNAGYCCNYTNCAYCARAARAARGCNTTYYTNACNAARAARGGNATGACNCARGAR GARATHGAYYTNGCNGTNACNMGNGCNGGNGTNACNGAR------ACNGCNGCNAAYAAY GTNGGNGTNCAYCARGGNCCNCCNCCNGGNTAYCARCCN---------------GGNATG ATHGTNCCNTAYGGNCARGTNCAYCCNCCNATHCCNCCNCARTCNMGNTGGGCNCARGTN MGNGAYTGGACNYTNGCNTCNGTNGTNGTNGCNGGNGTNTCNTAYGCNATHTAYCAYYTN TTYAARACNTAYYTNGARCCNYTNATHMGNGGNAARAAYGCNCARGARAARMGNATHGAY MGNYTNGARYTNCARGTNGARGARATHCAYAARTCNGTNAAYAAYTCNYTNACNGAYATH AGYMGNACNYTNGCNGCNATHCARYTNAGYATHAAYAAYCARAGYCARCARTCNGTNGCN AAYCARAAYGTNGGNMGNGGNATHACNGAYYTNAARGCNGAYATHTCNTCNYTNMGNAGY YTNYTNYTNAGYAARCAYGGNAAYTAYATHGTNGARGARGARYTNACNATHACNGCNAAR ATHGCNAARTGGTGGMGNCARAARMGNYTNCARGGNAAYGTNCARATHATHCCNAARTGY GGNCCNAAYTCNATGATHCAYCAYATHTCNMGNYTNCCNGARTGYCARAGYTTYYTNCAR AARGARAARAARAARYTN---YTNYTNATGAGYGARATGTCNGAYAARAARGCNGAYAAR TTYGCNTCNYTNGCNAGYYTNGARGAYTAYYTNGCNAAYTTYAAYTCNGCNYTNAAYTAY ATHGAYCARGCNYTNCAYATHCARCCNAAYTGYCCNGARTAYYTNTGGYTNAARGARAAR YTNTCNMGNCARTGYCARGTNYTNMGNAARCARAAYAAYGCNYTNMGNACNATHGAYGAR AAYCAYYTNCARTTYCCNTCNATGAAYGARGTNTCNMGNATHTCNGGNAARGAYYTNAGY GTNGCNGAYTTYAARAARAAYTAYYTNATGGTNAAYAARCCNGTNATHATHACNGAYGTN GTNGTNGAYATGACNAAYGAYCCNTTYGAYTAYTCNYTNGTNYTNAARCAYGCNGGNAAR ACNACNGTNACNACNAARGARGARGTNTCNGARTCNYTNACNTGGGCNMGNYTNGARAAY AARMGNGAYACNAGYATHGCNGCNYTNATHCARGGNGTNCARACNGGNACNGTNAARGAY GTNYTNTTYGAYTGGAGYYTNCCNATHCAYTGYCCNAGYYTNGCNGARCARATHTCNYTN CCNMGNTAYTTYACNGAYAAYTTYYTNYTNCARACNGCNCCNGARTCNYTNTAYMGNGAR AGYTGGCCNAGYYTNTTYATHGCNCCNAARGGNGCNACNACNCARYTNCAYGTNGAYGCN TTYCAYTCNCAYTTYTGGATGGCNYTNTTYCARGGNGARAARMGNTGGACNTTYTTYGAY GARAARGAYACNCCNTTYYTNTAYCCNGARTGGTTYCARTCNATGGAYCCNGTNTTYCAR GTNGAYCCNTCNCARCCNAAYYTNAARMGNTTYCCNYTNTTYGCNYTNACNMGNCCNCAR CARTGYGTNYTNCARAARGAYGARYTNYTNTTYGTNCCNGCNGGNAGYCCNCAYTTYGTN GARAAYYTNACNCCNTCNYTNGCNATHTCNTCNAAYTAYGTNGAYCAYTCNAAYTTYAAY AARGTNTGYGARGARYTNAARATHAAYGCNTTYCARGAYGARMGNGCNGGNGAYYTNYTN TCNCARYTNCARGAYCCNATGTTYCARCAYAARGTNCARAAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GAYGARGARGAYGARGARGARGGN ATHTAYGARAAYGARCCNGTNAARMGNGAYGAYGTNGCNMGNGARTCNGAYAARGGNGAR GAYACNAAYYTNCCNTCNCCNGGNYTNGCNCARAAYYTNYTNGCNAARTTYACNACNGGN ACNGCNAGYAAYTCNACNCCNMGNTCNAARMGNGARATHACNCCNCCNAAYCCNACNATG GGNGGNGGNGARTAYGTNTCNGARCCNMGNGTNGTNATGGARMGNTAYGARGGNAARGCN GARTCNGGNGTNTTYGARAGYGARCCNCARCAYAAYCCNGARGTNGTNMGNTCNGAYTCN CAYYTNGARGARGCNYTNCCNGARCARGGNTCNGCNAARAARTTYGCNGCNMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------TTYTCNGTNCCNGTNGAYCCN GARYTNGTNATHATHGTNTCNGCNACNCARGAYGCNTAYATHCCNMGNGAYGGNGTNYTN CCNYTNGAYGARYTNTGGCCNGGNTGYGARGTNMGNTAYGTNGAYCARGGNCAYATHGGN GCNGTNYTNYTNCAYCARAAYGTNTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGAAYMGNAGYATGAAYACNAARYTNATHCARGCNTCNYTNAGYCARAAY ACNMGNGARGGNYTNTTYTGYAARTAYAGYCAYMGNGAYTGYACNCARAAYTGYYTNGAR GGNTAYGARTAYTGYATHMGNCAYATHYTNGARGAYAARACNGCNCCNTAYMGNCARTGY GCNTAYATHACNAARGCNGGNMGNAARTGYCCNTCNGCNGCNCCNAARYTNGARAARAAR GARGGNTTYTGYGGNTTYCAYACNAARAARGCNYTNYTNACNMGNCARMGNYTNGCNMGN AARMGNMGNCCNAARGARACNCCNGAYAGYYTNYTNGARGAYYTNGTNGCNACNACNTCN ATGATGGAYTCNAAYCAYAGYGCNGARCCNMGNMGNGGNAARYTNCAYAGYGAYAGYYTN GCNTCNAARGCNYTNGARTAYGCNAGYTCNAGYGAYTCNGARACNGARCCNYTNYTNGTN GARCAYTCNTGGMGNGAYTCNGGNGAYAGYGAYGCNGARAGYATHGAYAGYGAYCARGAR GAYGTNYTNAARTAYGCNGGNGTNTAYACNACNGARGARGTNGCNCARATHYTNMGNGAY AARYTNATHMGNYTNCARGCNYTNTAYATHGAYCARTTYAARMGNYTNAARCAYATHYTN TTYACNAARMGNGGNAARTAYYTNCARGCNCARCARAARGARAARGARYTNTTYGGNAGY ATHAARMGNTAYAARGAYGAYCCNCARCARMGNGARAARTAYAARAARYTNTGYGCNATG AARMGNTAYCAYAARAARTTYGGNGTNGARGCNYTNATGCARCAYAARTCNACNCARMGN MGNATGAARATHACNGARGGNATGAGYCARAAYATHCCNACNCCNGTNCARTGYAAYTTY GTNGAYGAYGARYTNMGNTGYTCNCARGCNGTNGTNCCNYTNAGYAARTAYTGYCARAAR CAYATHYTNCAYGAYCARAAYCARGTNYTNTAYMGNCCNTGYCCNTTYGCNGAYAGYCAR TGYGGNMGNCCNGTNCCNTCNYTNYTNGGNAGYCCNTTYTGYTCNYTNCAYCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GARATGATHAARTCNYTNGAYAARGAY GTNTCNGARYTNAARGTNAGYAAYMGNGAYYTNCARAARGAYATGGARTCNTGYMGNGAR MGNGARTCNAARATGYTNTCNYTNCARTCNGARYTNAGYMGNACNAAYGCNTGYYTNMGN TCNGARAAYACNACNYTNAGYAAYAARGCNACNAAYYTNACNGCNGARGTNGARMGNYTN AARATGGARATHCARGARYTNGARACNACNGTNAARCAYYTNACNGAYTCNGTNGARGGN GARAARAARAAYAAYGCNCARACNATHGTNAARYTNAARGCNTCNYTNGARGARAARACN AARGARAGYTGYGAYYTNAARCARAARTGGGARGAYGARATHGAYTCNAAYAARACNYTN AARMGNMGNCAYGCNAAYAAYGTNAARGAYYTNACNMGNCARYTNCARCARGCNAARMGN MGNYTNGARATGGTNGARGGNAAYMGNAARGAYAGYTCNGGNAGYATGGGNTCNMGNACN AAYTCNAAYGGNAGYYTNAAYTCNATGGGNGGNGTNGCNGGNGCNGCNCAYCAYGGNACN TCNTCNGCNAAYACNCARGARTTYCCNGTNATHACNGARCARGTNGARATHGAYAARCAR GTNYTNATHGARMGNATHGTNMGNYTNCARAARTCNCAYGCNMGNAARAAYGARAARYTN GARTTYYTNGGNGARCAYATHCARCARYTNYTNGAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARGCNAAR MGNGAYGGNGAYGARAGYTTYCARACNTTYATHYTNCAYGAYGARAAYCAYACNYTNGGN AAYGCNYTNAARTAYATHYTNAAYAARAAYCCNGAYGTNACNTTYGTNGGNTAYAGYATH ACNCAYCCNTCNGARAAYAARATHAAYYTNMGNATHCARACNACNGGNAARCCNGCNATG CARGTNYTNGARCARGGNTTYAARGAYYTNAARCARYTNTGYGGNCAYATHYTNACNACN TTYGARTCNTCNACNAARTAYTAYAARGARAAYCAYATGGAYCCNGAY---GAYATGGAY CARTCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------YTNGAYAAYGGNGARCCNATGGCNTGYGAYCARCAY TGYAARCCNTCNATH---CCNYTNGCNATGTGGGAYTTYGARCAYTGYGAYCCNAARAAR TGYACNGGNAARAARYTNAGYMGNGTNGGNTTYGTNMGNACNYTNMGNYTNAAYCARMGN TTYAAYGGNYTNATHYTNTCNCCNATHGGNACNAARTGYGTNGCNCCNGAYGAYMGNAAR ATHGTNGARATGAAYGGNGTNGCNGTNATHGAYTGYAGYTGGGCNAARYTNCARGAYACN CCNTTYGCNMGNATGAARGGNGAYCARYTNMGNYTNYTNCCNTAYYTNATHGCNGCNAAY CCNATHAAYTAYGGNMGNCCNTGYAARYTNTCNTGYGTNGARGCNTTYGCNGCNACNYTN TAYATHACNGGNTTYGCNAARGARGCNGARATGYTNYTNAARAARTTYAARTGGGGNMGN TCNTTYTCNTCNYTNAAYAARGARYTNYTNGAYACNTAYAGYAARTGYAGYACNAGYCAR GARGTNGTNTCNGARCARGARAARATHYTNGCNCARYTNGARGARGAYGGNMGNCARAAY AARYTNAARGAYTGGACNGARATHGAYATGACNACNGAYGTNTGYAAYCCNAAYMGNCCN ---------ATHTCNGARTCNAGYTCNGARGAYGAYACNGARGARGARAGYGARGARGAY GARGAYAGYGAYMGNGAYAARGAYYTNGARTCNGCN------------------GARATH CARAARGAYGGNATGGAYTGYGTNGCNGCNCAYACNGAYCCNGARTTYATHATGGCNGTN TAYAARCAYATGAAYAAYCCNGAYGARATGGCNAARCCNACNTTYATHTGYAAYTAYCAR AARGARYTNGTNAARATHGTNATGTGYATGAARGAYAARGTNGARMGNTGYYTNCCNAAR GARTTYAARACNYTNATHGAYYTNATGATH---GTNGARAARAAYATGGCNGARGGNATG AARTTYATGTGYGAYCAYAARGAYATHYTNCARGAYAARTGYATGGAY---GAYAAYGTN CARGAYTTYGCNCARTGYTAYATGAGYMGNYTNTCNGTNYTNCARAAYAARGTNGCNTCN ACNACNGAYYTNAARAGYYTNAGYAGYYTNATHTGYAGYGTNGTNMGNACNGARGARCAR TGYTTYMGNGARAAYAARGGNTCNTGYTCNAARAARTTYATHGARATHGTNGTNGARACN YTNGARAARTTYTTYCCNATGTCNTCNTGYCCNAARACN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARTCNTAYAARACNGARCARGTNYTNTCNYTNCARGTNTAYAARYTNCARCAR GARCARAARACNYTNTCNGARGARAARGARAARAGYAAYGGNGARMGNGAYTCNYTNAAR AAYCARYTNGARGARGCNAAYTCNGARYTNTCNAAYYTNMGNAGYCARYTNGARYTNCAR TCN---------AARYTNMGNGARAAYATGGAYTCNCCNGARTCNAAYGARGARYTNGCN ATHAARAAYAARGARGTNATHAAYYTNCAYACNCARYTNCAYACNTAYCARGTNGAYATG GARAARAARAAYAARGARYTNGGNGARAARGCNAARGARYTNATHACNTAYAARGARGAR GTNGARAARYTNAARGARGARYTNGGNMGNYTNAARAAYCCNCCNGTNATGTGYGARACN TCNAGYCARACNCAYGCNYTNTGYGARGTNTCNAAYYTNGARAAYGTNAARCCNTCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GCNGCNACNYTNAAYYTNGCNTGYYTNATHTAYATGYTNCARTGGYTNCCNACNGCN GARTCNYTNATHCCNTAYTTYGTNATHATGGGNATHTGGGGNATHACNGAYGGNTTYTGG ACNGCNCARGTNACNAGYYTNATGGGNYTNATHTTYCCNGAYAARATHGARGARGCNTAY GCNGGNYTNMGNATGACNCARGGNYTNAGYGCNGCNATHACNTTYGGNTAYTCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GARTTYCCN GGNAARGARATHATHGTNATGCAYAAYGCNAAYGTNATHYTNCARTTYCCNTCNTCNTCN ACNYTNGAYGARTGGGGNAAYGTNYTNGGNGAYCARATGMGNCCNMGNGTNGTNAARMGN GGNGTNGAYGAYTTYGCNACNATHGARTAYGGNGARMGNGARGARATHGAYCAYYTNGTN TTYTTYGTNCCNGGNATHGARGARATGACNGAYGGNCARCCNAARTCNYTNGARGARTAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CCNCCNAAYAARAARCCNAARYTNAARGGN MGNAAYAARCARMGNCCNAARAAYGARMGNATHGARCARAARGAYAARYTNTGYCCNTCN ATHAARGTNGGNAARGARTGYAARTTYGGNGAYAGYTGYAARTTYYTNCAYGAYATHAAR GARTTYYTNGARAARAARMGNCCNGAYATHAARGARAARTGYCCNGTNTTYGARACNYTN GGNTTYTGYAARTTYGGNGTNACNTGYMGNTTYGCNAGYAGYCAYYTNGGNGARAAYGGN GARAAYMGNGTNAAYCARGARYTNTAYGAYACNATGAARGAYAARCCNYTNTGYATHAAY GTNYTNAGYGARGAYGTNMGNCAYAARYTNTGGAARMGNAARTAYGAYTTYTCNAARGCN ATGAARTCNGTNAAYCAYATHCARAARACNTTYMGN------------------------ ------------------------------------------------------AAYGAR AAYAARACNGAYATHACNTCNTCNTGYGAYAARGARGARCARAARGAYTGYGTNACNGAR GTNGARCARGARYTNTCNCARGAYACNACNGAYACNGCNGAY------------------ ------------------AARGAYTCNAGYTCNGTNGTNYTNGARCARGARTCNGAYAAR MGNYTNGCNGARCAYYTNACNGAYGAYGTNCARATHMGNTCNACNTCNMGNGARGTNAAR AARATHGAYTTYCAYAAYAARYTNTAYYTNGCNCCNYTNACNACNGTNGGNAAYYTNCCN TTYMGNMGNGTNTGYAARGAYTAYGGNGTNGAYATHACNTGYAGYGARATGGCNYTNGCN TCNCARATHYTNAARGCNAARGCNTCNGARTGGTCNYTNATHAARMGNCAYCCNAGYGAR GAYATHTTYGGNGTNCARATHTGYGGNGCNTAYCCNGAYATGATGACNAARTGYGCNCAR GTNYTNACNGARACNAGYGAYYTNGAYTTYATHGAYATHAAYTGYGGNTGYCCNATHGAY YTNGTNTTYAARAARGGNAGYGGNAGYGCNYTNATGGGNAARGTNACNAARYTNGARCAR ATHTGYMGNAGYATGMGNGGNGTNATGGGNGARGTNCCNYTNACNGTNAARYTNMGNACN GGNGTNTTYGAYAAYAARAGYACNGCNCAYACNATHATHCCNMGNYTNMGNGAYGCNGGN GTNTCNYTNGTNACNATHCAYGGNMGNTCNMGNGARCARMGNTAYACNAARYTNGCNGAY TGGGAYTAYATHGAYMGNTGYGCNAGYYTNGGNMGNCCNATGCCNGTNTTYGGNAAYGGN GAYATHYTNTCNTAYGARGAYTAYAAYYTNCARATGGARMGNAARGGNGTNTCNGGNGGN ATGATHGCNMGNGGNGCNYTNATHAARCCNTGGATHTTYACNGARATHAARGARCARMGN CAYTGGGAYATHTCNTCNTCNGARMGNTTYGARATGYTNMGNTCNTAYACNAAYTAYGGN YTNGARCAYTGGGGNTCNGAYGAYCARGGNGTNGARCARACNMGNMGNTTYYTNYTNGAR TGGYTNTCNTTYYTNCAYMGNTAYATHCCNGTNGGNGTNYTNGARCARGTNCCNCARAAR ATHAAYGARMGNCCNCCNTAYTAYATHGGNMGNAAYGAYYTNGARACNATGATGGCNAGY GCNAAYTGYGCNGAYTGGATHAARATHAGYGARATGYTNYTNGGNCCNGTNCCNTCNAGY TTYCARTTYYTNCCNAARCAYAARGCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GTN CARAGYGARGCNGAYGCNATGATGGARMGNCARAARAARGAYATHYTNCCNGGNYTNACN TCNGGNAGYAARACNTCNYTNAARMGNGGNGAY---GGNGAYACNGARMGNATHATHGAY CCNACNACNGTNGAYGGNGTNGARGAYGAYAAYAAYTAYTCNGTNTTYGTNTCNTAYATH GARATHTAYAAYAAYTAYGTNTAYGAYYTNYTNGARGARYTNCCNTAYAAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYCAY GAYMGNTTYGCNGARYTNGARAARGARATGGARGARYTNMGNGGNMGNYTNATHGARAAR GAYGGNATHGTNTCNGAYYTNCARMGNTCNAAYTCNTCNYTNYTNGARYTNYTNGARAAR AARGCNGAYGGNGAYAAYAAYYTNGARAAYMGNYTNGCNGGNCAYAARYTNGARGCNGAR YTNAARAAYYTNMGNGCNGARMGNGARCARATGGTNGCNGTNGTNAGYGARAARTCNMGN GARAAYTCNTCNYTNAARTCNGARATHCAYMGNYTNATGGAYYTNGTNGGNGCNGGNCAR GCNGCNYTNGCNAARGTNCARCARGAYAAYYTNACNYTNGARCARMGNCARAAYTCNCCN CCNMGN------GARMGNGARGARGAYGARATGAARMGNGARGCNYTNAAYAAYATGGCN MGNYTNGTNMGNGAYAARGAYACNGARATHGARGCNYTNACNCARAARAAYAAYACNYTN YTNGCNGTNYTNCARGAR---TCNAAYGARTCNAAYGCNGCNGCNCAYYTNGGNCCNYTN YTNAAYGARAARGARGCNYTNAAYMGNCARATHAAYTCNATGYTNACNGARMGNGARCAR YTNATHACNTGYGTNACNCARAARCAYTCNGARTCNYTNGCNTTYCAYGCNGARGTNCAR MGNYTNACNGGNYTNYTNGTNGARTCNCARGARGCNGCNGARAARGCNAARGCNGARTAY GCNGCNYTNATHCCNTCNTTYGARGGNAARAAYCARGCNYTNYTNACNACNCARCARGAR YTNATHGARTCNAARCARAARYTNTCNGARYTNGARATHMGNCAYGGNGARYTNATGCAR MGNTCNAAYAGYCARCARCARYTNAGYCCNAGYTCNACNGAYGAYYTNGARATH------ ------------------GARAARTAYAARMGNYTNGARTCNGAYTAYAARTCNATGGTN YTNGARMGNGAYGAYCARATHCAYAGYYTNTCNCARAARGCNAARYTNAAYGARGARGTN GTNGCNTCNAARGARGCNGARTGYACNCAYYTNMGNAARCARYTNGARAAYTCNAARTTY CARYTNACNGGNYTNATGGCNGARATHGCNGAYGTNAARTCNGAYMGNGARYTNATGCAR CARAARAGYGAYAGYAARGGNGARGARTCNGTNAGYYTNMGNAAYAGYYTNAAYCARATG ACNYTNACNGTNAARGAYAARGARGCNGARATHYTNTCNYTNAARGAYCARATHGCNACN YTNAAYTCNGTNYTNCARAAYCARAARGGNGAYGARGAYCARGTNAGYCARYTNATHMGN GAYCAYGARYTNGCNGTNGCNGCNACNMGNCARYTNCARCARGARACNGAYMGNAAYGCN ATGYTNGCNGARCARMGNTTYCARGARTGYGARGCNYTNAARACNGARATHTCNTCNCAR AARGAYAARYTNTTYAARATGGGNMGNGARYTNGARMGNYTNMGNAGYCAYYTNATHGAR ATHGARGARGGNTAYACNAARGARGCNYTNGARGCNGARGARMGNGARAARGARYTNMGN AAYAARYTNGCNGTNGCNGARGARCARYTNATGACNTCNTCNTCNCAYGTNCARYTNGCN AGYCARGARTCNCARMGNCARATHGARAGYYTNCARGAYCARYTNCAYCAYATHGCNTCN CARMGNGAYGCNGCNTAYATGCARGTNGCNACNACNCARGAYCARTGYCARCARTAYGCN GCNTCNYTNAGYAAYYTNCARYTNGTNYTNGARCAYTTYCARAARGARAARGAYTCNGCN ATHGCNYTNGARACNGARAARTAYCARGAYCARGCNAARTGYYTNAGYGCNGARGTNAAR GARYTNGARAARGARYTNGARGCNACNMGNGGNGAYYTNACNGARGCNYTNGAYGGNYTN GARGCNGCNTCNMGNYTNAGYGARCARYTNGAYMGNAARGARGARGCNYTNATGGCNYTN AARGARGARGTNCARYTNMGNGARGARGCNYTNAARGGNGCNGARGCNGARATHGCNAAR YTNAAYTCNAGYAARGARGCNAARGTNGAYAARACNYTNATGCAYAAYATGGTNYTNACN TGGYTNACNTCNCCNGARAARAARMGNCARGARATHGTNCARYTNATHGGNCAYATHYTN GAYTTYAGYCCNGAYGAYTTYTCNAARATHGARTCNGCNCAYAGYCARGAYAAYYTNTGG ATHGGNTTYTTYAARMGNTCNGCNCCNAARTCNACNCCNACNACNCCNAGYAARGTNGAY CARTCNTTYTCNCARYTNTTYGTNAARTTYYTNGARAARGARTCNTCNCCNGCNCCNGCN CCNGTNCARYTNCCNGTNGARGCNATGGCNGCNGARGCNCARCARMGNCAYAARACNACN TTYAAYCCNTTYATGGCNCCNMGNCAYGTNACNCAYGGNAAYGARGGNYTNGGNTCNTCN TCNGGNCCNTCNTCNCAYYTNYTNATHCCNCARGAYAAYCCNCAYCCNTCNCCNYTNTTY GCNCCNGTNACNAGYGTNTCNMGNGCNGGNGARAGYGCNATHYTNAARGAYGTNYTNTGY TTYGTNTAYGGNGARMGNATHMGNTCNTGYACNGARCARTCNGGNAAYYTNYTNTGYCAY TCNGARGCNTCNMGNTTYATHTGYTGYACNGGNGAYTAYTGYAAYGARAAYYTNCCNCCN CCNYTNCCNCARCARCARCCNGCNATGGGNATGGCNGARGARAGYAGYTCNCARAAYATH ACNATHATHACNATHGCNATHCCNATHATGGCNGTNATGYTNGTNGGNGGNYTNYTNYTN TTYTAYMGNTGGCAYMGNAAYMGNAARMGNGGNCCNAGYTCNYTNATGTCNGARAAYMGN YTNYTNGARGARGARGGNTCNGGNTCNAARGTNTTYGGNGAYCAR---TCNTCNGGNAGY GGNTCNGGNCARGCNAARYTNGTNACNMGNACNGTNGGNAARGARGTNCAYYTNATHGAR AARATHGGNAAYGGNMGNTTYGGNGAYGTNTGGMGNGGNAARTGGYTNGGNGAYGAYGTN GCNGTNAARATHTTYACNTCNYTNGARGARACNAGYTGGMGNCARGARATGGAYATHTAY AAYACNGGNATGYTNAGYCAYGARAAYATHYTNGTNTTYCAYGCNTCNGAYACNATHGGN MGNTTYTCNTGYACNCARAAYYTNYTNATHGTNCARTAYCAYCCNAAYGGNTCNYTNTAY GAYTAYYTNCARMGNTCNGAYATHGAYATGGARGARATGYTNATGYTNGCNAGYACNGCN GCNGCNGGNATHAGYCAYYTNCAYTAYGARATHAARCARGGNACNGGNACNCAYGARAAR CCNTCNATHGCNCAYMGNGAYATHAARTCNAARAAYATHYTNGTNAARYTNAGYGGNGAR TGYTGYATHGGNGAYYTNGGNCAYGCNATHAARAAYACNAARGARTGGGAYMGNGGNMGN GARMGNYTNTGGATHGGNACNAARMGNTAYATGGCNCCNGARYTNYTNGCNAARACNYTN AAYCCNGCNCAYTTYGARTCNTTYMGNTGYGCNGAYGTNTAYGCNTTYGGNYTNGTNYTN TGGGARATHGCNMGNMGNGCNMGNCCNTAYTGYGAYGAYTAYMGNGTNCCNTTYTGGGAY ATGGTNCCNGCNGAYCCNAGYYTNGARGARATGAARGCNGTNGTNGTNGAYMGNCARCAR MGNCCNGCNATHCCNAAYAAYTGGTCNCARGARCARYTNATGYTNGARATGGARAARYTN ATGMGNGGNTGYTGGGCNCARCAYCCNTCNAAYMGNYTNAAYATHYTNMGNGTNAARAAR AAYYTN---CARGCNYTNMGNTCNCAYAAYGARCARATGATGGARAARMGNGARAARYTN ACNGGNAARATHYTNGAYGGNAGYACNACNACNAAYAGYGTNGTNACNACNTCNAGYAAY ATGYTNTTYAAYYTNGAYGAYTGGAARCARGGNATGATGYTNYTNTGYGAYGAYYTNAAY MGNAARYTNGTNTTYMGNAAYCAYTTYGAYTGYYTNTCNMGNTAYTCNAAYMGNATHTCN AGYTGYATHYTNATHMGNACNCARATGTTYMGNAARGCNATHTTYGAYGCNGGNATGGCN AAYMGNAARACNYTNCAYGAYATHACNTGYAAYTTYGCNGARAAYATHGTNAAYTGYYTN GARMGNCCNYTNGGNMGNCARTGYCCNATHCARGTNGTNGAYACNATGGTNTCNGCNYTN CAYMGNTTYYTNCCNCCNGCNTGYGCNCCNYTNCCN------------------------ ---------GCNAARGAYGCNAGYGAYACNACNGTNATGGARACNGTNATHYTNGARGGN GGNGGNGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TAYATH CARGCNTCNAGYAGYGCNCCNGAYCCNGAYATHTCNAGYCCNYTNGTNGAYGGNTCNYTN GGNGGNGCNGARTTYATHCCNTCNAAYTTYGAYYTNYTNGGNGAYYTNTGYTCNGTNGAY CARYTNGARYTNGGNAAYATHYTNACNGAYAGYGAYYTNATHGARYTNAARCCNTCNYTN GGNACNGARGGNYTNAAYCARGCNTCNYTNGTNACNGGNTTYGAYGGNYTNGAYGCNGAY GGNTCNACNGTNGCNGTNAAY---------TCNTGYCCNACNGGNAARTAYCARTCNGCN GAYATHATHCAYGCNGGNATH---TCNGTNCARGAYGARYTNTGGMGNAARGARMGNATH AARAARGAYAAYCAYAAYATGATHGARMGNMGNMGNMGNTTYAAYATHAAYGAYMGNATH AARGARYTNGGNGGNYTNYTNCCNAARACNATGGAYCCNGAYTCNMGNCARAAYAARGGN ACNATHYTNAARGCNTCNGTNGAYTAYATHMGNGTNYTNCARGARGARCARMGNMGNTTY MGNGGNATGYTNGAYGARAARAARAARGCNGARYTNGAYYTNMGNAARGTNYTNATHMGN YTNAAYCARATGAAYYTNGTNATGAARTCNCAYGGNATHGARTCNGGNAGYYTNGAYGAY YTNGARYTN---TCNTCNAAYGTNGCNACNAGYCCNYTNACNYTNACNCCNTCNTCNCAR GGNACNCCNGTNAGYACNATHATGACNAAYAAYAAYCAYGTNTTYYTNACNAGYACNYTN ATGTCNCCNGTNGAYGAYYTNATG------GAYGARTCNCCNGTNAGYGGNGAYCCNATG YTNATGTCNGCNCCNGTNAGYCCNGAYCCNGAYGARGTNGGNTTYCAYTTY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARGARYTNCAYYTNCAYACNGTN ACNYTNCARATGGCNATGGARTCNTTYGAYAGYCAYGGNYTNMGNGGNMGNAAYGAYAAR YTNATGGAYGTNGGNGARATHATHGARTGYYTNTCNTCNATGATGGARACNGCNGCNGGN CARCAYCCNGAYGTNGTNAAYGTNCCNYTNTCNGTNGAYYTNACNYTNAAYTGGATHYTN GAYGTNTAYGAYAGYGTNMGNAGYGGNAARATHMGNGTNYTNTCNTTYAARGTNGCNGTN GTNYTNYTNTGYCARGCNCARYTNGARGAYAARTAYMGNTAYATHTTYMGNYTNATHGCN GAYGCNAAYGCNTTYGCNGAYCARMGNAARATGGGNYTNYTNYTNCAYGAYTGYATGCAR ATHCCNMGNCARYTNGGNGARATHGCNTCNTTYGGNGGNAGYAAYATHGARCCNAGYGTN MGNAGYTGYTTYGARAARGCNAAYGGNMGNCCNGARATHGARGCNTAYCAYTTYYTNGAY TGGYTNAARYTNGARCCNCARTCNATGGTNTGGYTNCCNGTNYTNCAYMGNGTNGCNGCN TCNGARACNTCNAARCAYCARGCNAARTGYAAYGTNTGYAARGAYTTYCCNATHYTNGGN TTYMGNTAYMGNTGYYTNAARTGYTTYAAYTTYGAYGTNTGYCARAAYTGYTTYTTYTCN GGNMGNACNGCNAARAGYCAYAARYTNGCNCAYCCNATGCARGARTAYTGYACNACNACN ACNTCNGGNGARGAYGTNMGNGAYTTYTCNAARGTNTTYAARAAYAARTTYAARTCNAAR MGNCAYTTYAARAARCAYCCNMGNMGNGGNTAYYTNCCNGTNGAYTCNCAYYTNGARGGN GAYAGYYTNGARAGYCCNAAYCCNTCNCCNCARCAYAGYATHTCNCARGAYATGCAYTCN MGNYTNGARATGYTNACNAGYMGNATHGCNGARGTNGARCARMGNCARGGNGGNCCNGCN GAYYTNGARGAYGARCAYCAYYTNATHGCNCARTAYTGYTCNAGYYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ACNCARATHAGYMGN GCNYTNAAYTAYYTNAAYYTNTGGAARTAYAAYTTYMGNTCNTGGAARTTYAGYAARYTN TAYCARATHMGNYTNATGAARATHYTNTAYAAY---CCNGCNGTNACNGARAARGAYTTY GARACNTGYYTNCARTAYTTYGARAARAGYCARGGNAARGCNMGNGARCARYTNAARGCN GAYGCN------------------------------------------------------ ------AARYTNATHAAYATHGCNAAYGARYTNTTYGGNTTYACNGGNTGGTCNCAYTCN GTNAGYAAYCARACNGTNGAYTTYGTNGAYCAYATHAAYGGNAARTAYTAYGTNGGNGTN TCNGCNACNGTNMGNGTNATGYTNAARAGYGGNGTNTAYCAYGARGAYGTNGGNTAYGGN GTNAGYGARGGNATGMGNTCNAARGCNYTNTCNYTNGARAARGCNMGNAARGARGCNGCN ACNGAYGGNYTNAARMGNGCNYTNAARAGYTTYGGNAAYAGYYTNGGNAAYTGYYTNTCN GAYAARGAYTAYYTNAARTGYATHAAYAARGCNCCNGARCARCCNTCNCCNGCNTAYAAY YTNGARGAYATGAARMGNGCNACNGARGAYACNCAYGTNTTYAARGTNCARATGGCNGCN CCN---ACNAGYAARTCNTAYYTNCCNTGYGAYGAYTTYATGAARTTYCARGAYGCNYTN AARAARYTNMGNYTNATHGAYGAYMGNATHGTNCAYGCNYTNAAYAARAAYYTNCCNACN CARTCNTTYCARGGNAAYGTNGAYGTNGCNTCNAAYTGYMGNCAYATHTAYGAYGAYATH CARACNTCNTAYAAYCAYMGNGARAARTCNATHCARCAYTGYATHMGNYTNGTNAGYGAY GAYGTNAARAARYTNAGYGARAARMGNCARCARGAYCCNGAYAAYATGGAYGTNATHAAR GGNYTNMGNMGNGARCARACNAARYTNMGNYTNATGCARCARGARATGAAYGTNGARGAR GTNGTNAARGAYMGNACNYTNAARGTNATHGARGAYAARTGYGTNGARATHGCNGGNYTN TGYCAY------------------------------GAYYTNGGNCAYGGNCCNCAYTCN CAYATGTTYGAYGGNAARTTYATHCCNYTNGTNACNGGNAAYGAYGAYTGGAARCAYGAR GARGCNTCNYTNAARATGYTNGAYTAYYTNATHGARGAYAAYAARYTNATGGARCCNGGN GGNGCNYTNMGNMGNAAYMGNYTNAAYAARACNGAYATHATHTTYATHAARGARYTNATH AAYGGNCCNYTNGGNGAYAARGAYACNGAYTGGCCNTAYYTNGGNMGNGGNAARGARAAR GCNTTYYTNTAYGARATHATHTCNAAYAARYTNACNGGNATHGAYGTNGAYAARTGGGAY TAYTTYGCNMGNGAYTGYCAYCAYYTNGGNATHGTNAAYAAYTTYGAYCAYAAYMGNTTY ATHAARTTYGTNMGNGTNYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GGNGCNACNAAYTTYCARATHCCNCARCAYYTNGAYYTNGGNAAY CARCAYACNTTYGARATHAARGAYYTNGARAAYYTNATHAARAARACNACNAGYGAYYTN GARCARYTNGARNNNAARAARAARAARGAYTTYAARGARTAYGARATGGARAARAARTAY GARGARGARGARMGNYTNMGNCARYTNAAYGARGARGARMGNAARAARGARCARGARMGN ATHGAYGARYTNAARMGNAARCAYAARGAYCAYCCNAARYTNCAYCAYCCNGGNAGYAAR GAYCARTTYGARGARGTNTGGGAYAARGARGAYCAYYTNGARGGNCARGAYTTYGAYCCN AARACNTTYTTYAAYYTNCAYGAYATHGAYGGNGAYGGNGARTGGAAYATGGARGARGTN GAYGCNYTNGTNGARMGNGARYTNAAYAARGTNTAYGAYMGNAAYAAYGAYCCNAARGAR GAYGAYCCNMGNGARMGNGAYATGGARATGGAYAARATGMGNGCNGAYATHTAYGARGCN ATHGAYAARGAYAARAAYYTNMGNATHACNMGNGARGARATGYTNGCNTAYACNGGNYTN CAYGGNGARAAYAARGAYTTYCARAARGAYGARGGNTGGAARACNYTNGAYGARGARCCN GTNTTYGAYGARGARGARTAYMGNAAYTAYATHMGNGARCAYCAYCARCARCCNGGNGTN GTNGAYGCNCCN---YTNGAYYTNCARTTYAAYTCNGARAGYAAYYTNCARCARCARCAR TTYAAYCARCARCCNMGNCARCARCARCAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CARAARTGYGARTTYTCNYTN ACNGTNGGNAARCAYACNGCNACNATHGTNGCNAARAAYAARMGNGAYGGNAARCARYTN GCNGCNCARGCNATHYTNGCNAARYTNCAYCCNCAYGTNCCNGGNTGGGGNTCNYTNYTN MGNYTNTAYGCNACNAAYGTNGARAARCCNATGGARAARGTNGARGARATGAAYGARATH AARACNCAYGTNCCNAAYAARGCNGTNYTNGARAAYYTNMGNGARGARATGMGNAARYTN CAYAARCARAARGARGCNATHCARTCNAARGGNAARATGYTNATHTCNACNAARGAYYTN CCNAGYAARATGTCNGTNGTNGAYTTYATGGTNGCNTTYGGNYTNCAYYTNGGNGCNTGY TCNGCNTGYYTNGCNGTNCAYMGNGAYGGNAARACNGARGTNATHGCNAAYGAYYTNGGN GAYMGNGTNACNCCNACNGTNGTNGCNTTYACNGAYCAYGARATHGCNGTNGGNGCNGGN GCNAARCARGGNGCNATHMGNAAYGCNGCNAAYACNATHGCNCAYGTNAARCAYATHGTN GGNAGYGARGGNGARGAYGCNCCNGTNAARGARTAYATHCARAAYCAYCARGTNGAYGTN GTNGAYCARAARGGNTCNYTNATHTTYAAYGTNGARTAYCARGGNAARAARGTNCARTAY ACNCCNAGYAARATHYTNGARYTNATHTAYAAYAARATGYTNGARACNGCNCARAGYAAY GGNGGNGGNGGNACNACNGAYGCNGTNYTNGCNGTNCCNTCNGAYTTYACNCARAARCAR MGNGAYATHYTNAGYGARGCNGCNACNAARGCNGGNTTYAARGTNYTNMGNATGATHAAY GARCCNTCNTCNGCNATGYTNGCNTTYGAYGTNGGNCARTTYGAYGARTCNGARCARGAR TTYAARACNYTNGTNTAYMGNTTYGGNGGNACNTCNCAYGAYGCNACNYTNGTNAGYGTN CARCAYGGNATGTAYTGYATHYTNGCNAARGCNTCNGAYAAYCARTTYGGNGGNGAYAAR YTNACNGARGTNYTNCARGGNYTNYTNGCNTCNGARTTYAAYMGNCARTTYMGNTGYGAY GTNAARGARAGYAARMGNTCNATGAGYAARYTNAARYTNGCNGCNGARMGNTGYAARCAY TCNYTNAGYTCNATGTCNAAYGCNCARTGYAGYGTNGARTCNYTNTTYGAYGGNYTNGAY TTYTCNTAYAAYGTNTCNMGNGCNMGNTTYGARAGYYTNTGYATGCCNYTNATGGCNCAR TGYACNCARYTNGTNCARCARGCNYTNACNAGYGCNGGNTGYTCNAARGARGAYATHTCN AARGTNATHYTNTGYGGNGGNGGNGCNAARTCNCCNGTNGTNAARAARGTNATGACNGAY TTYYTNCCNTCNTCNTCNYTNYTNAAYTCNATGCCNGARGAYGARATHATHGCNATHGGN GCNGCNAARGARGCNGCNYTNYTNGARGGNGAYGAYGAYGARAARGTNAARYTNACNGAR GARATGTCNAAYGCNTTYAARTCNYTNTCNAARGCNATHTGYATHMGNGTNAAYTCNCCN GAYYTNAAYGTNATHYTNCCNCARCAYTGYYTNATHCCNGCNMGNMGNCARCAYACNYTN ACNYTNCCNACNACNCARTCNAGYGTNAARYTNGARATHYTNCARGCNCARGARCCNATH AAYCCNGAYACNGARGCNCARYTNYTNGCNAARATHGTNYTNMGNGAYYTNCCNCCNGGN TCNAGYATHAARACNAGYTTYCAYYTNACNMGN--------------------------- ------------------------------------------------------------ ------------------GGNACNTAYTCNTAYGAYTAYCCNTCNAARMGNTAYMGNATH GAYMGNAARGAYGGNAARACNGAYMGNTAYTGY---GGNYTNAAYGGNTCNAARATHTTY TCNCAYACNCCNTGYTCNCARATHGTNAAY---GAYGGNGAYMGNTAYATHTAYTAYCCN GARAARAAYNNNTGYTGYTAYTGYTGYTCNGARGARCAYGGNTGYGGNATHYTNAARCCN GAYTGGATG---AAYGGNGCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARGARGAYGAYGARGARATHATHGGNMGNACNGAR GAYGARTCNGAYGAYYTNACNGAYTCNGAYGGNGAYGAYAARGCNGAYGARGGNGTNMGN MGNGGNGARCCNAAYAARTTYGAYGGNYTNTGYGAYGGNGTNATGAAYGCNATGGCNYTN GTNCAYGCNGCNYTNCARGAYYTNYTNGARATGAARGAYGARATGYTNMGNCAYTCNYTN CCNCCNACNYTNYTNGTNCARYTNGCNATGGTNAGYGGNMGNGTNTTYMGNAGYGTNAGY GAYYTNGGNAAYCCNGTNGGNGARYTNGTNMGNYTNGTNMGNGTNTAYTCNACNCCNTGG GARGARAARAGYGCNGCNYTNAARAARYTNCAYGARGAYTAYGARAGYAARCARMGNCAR YTNAAYATHGCNGTNMGNMGNYTNCARYTNGTNGAYGCNCAYTCNAARMGNGTNGCNAAR GARAARMGNATHATGAAYTGGGARAARYTNTTYTCNAARATGACNAGYGCNAARGGNCAY GGNMGNMGNTGGAARTTYYTNATHGARACNATHAARCARAARGCNAARYTNGGNYTNGAR CAYGTNCARGCNTAYACNCARAGYYTNGAYGAYTCNTCNGARTCNGARACNGARGARGCN GTNACNGARCARGCNGCNACNGTNGCNGCNGGNGAYGTNGAYGAYGTNAGYGARACNCAR GGNTCNCARGGNGTNGAYGGNACNGARGGNAGYMGN---------GARGAYAAYGARGAY GARGARGGNGARGARGARGAYGGNGARGAYGGNGGNMGNGGNGAYGARMGNGARGARATH GARTCNMGNGCNAGYGGNGARTCNGCNCAYTCNGARGGNGCNGARACNGAYGAYATHCCN ACNGTNTCNGTNCAYATHGGNCCNGGNGAYGAYGTNGAYATHGARGGNAGYTCNATHMGN TCNGCNTCNCCNAARAARGTNMGNTTYGARGAYAAYATHGCNACNTCNAGYTAYATHMGN CCNCCNATGMGNGAYTCNACNACNTGGACNGGNCARCCNGAYCAYGAYMGNTTYYTNTTY ATHMGNATHTTYTGYCCNGARGGNYTNGAYCARYTNGGNACNGGNATHAARTGYTCNYTN TCNTAYGAYGGNAAYATGTTYAARACNCCNGTNYTNGAYAGYCCNGARGAYGARTCN--- ---TCNGARGTNACNGARGARATHGARGARMGNCCNAAYCARMGNCCNCARGCNGCNMGN AARGCNGAYGARMGNTCNAAYGTNGAYGCNACNCARGARACNGAYTCNACNAARTCNAAR TCNAARAARTAYTAYGARTTYGARATHCCNYTNCCNGAYGARATHACNGARGGNATHYTN ATGYTNGGNGARAARCCNCCNCCNGARCCNGARAAYATHMGNATHGCNATHCAYCARGGN CARTTYGARGARATHATHGCNATGGCNACNATHGAYTTYYTNGAYATHAARGGNYTNAGY YTNGARACNATHTGGYTNCCNGCNCCNACNGGNGAYGAYGAYGTNGCNGTNGTNAARTCN MGNTCNAAYTCNYTNAGYGGNGCNTCNAGYYTNGGNGGNGARTCNYTNTCNGAYTCNATG GAYATHCCNATHATGATGGAYGAY------GAYCARTCNGGNMGNGGNYTNGTNTCNTCN ACNCCNMGNGAYGARATGYTNAARGCNAARGAYCCNYTNCCNTTYCCNYTNTAYCCNYTN CAYGGNGGNAARACNGAYTCNYTNCAYGTNCCNTGYGGNAAYATHCCNYTNTTYATGTAY TGGGGNAARMGNCCNMGNCCNYTNAAYTTYAAYMGNCARTGYGGNACNYTNGGNATHTAY GAYATHGTNTAYGAYATHACNGGNTTYGAYATGACNACNACNTCNAARGARGAYYTNCAY AARGARATGGTNGAYGARGCNYTNTCNGTNGCNGCNTTYACNCCNGAYCCNGAYGTNGAR GAYAARTCNACNGAYGTNGARGARACNGTNYTNAARTCNGARTAYGAYAARYTNGTNGAR MGNCAYCARGARGARATGGTNTAYYTNCARGARGARTAYGARAARMGNYTNCARGARYTN GTNCARAAYYTNCARACNATGAARGCNGAYAAYGAYCARGTNCCNCARYTNGTNTCNCAR CARTCNTCNCARCCNMGNCCNYTNTCNCARGCNTCNMGNGTNAGYACN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GCNATHTAYGAYGGNCARGGNACNCARAARYTNAGY TCNTTYGAYTGYCAYAGYAAYCARAAYYTNAAYMGNYTNMGNYTNGTNACNAGYGGNGAY ACNGTNACNTTYATHATGTCNMGNGAYAAYCCNAAYAAYCAYGAYTTYGAYATHGARATH MGNGTNAARCCNATHMGNGGNGGNGTNGAYCCNGAYTTYGAYAARCAY------GAYTAY TTYAGYTTYCARAARTTYGARCARGARGCNATHGTNGGNATGATHGGNGGNTTYTAYGGN YTNGTNYTNATHATHTGYATHGGNGTNGTNTGYTAYTGYAAYATHMGNTAYMGNGGNYTN AAYAARAARTGGGARACNCAYCARYTNGCNACNATGAARACNGAYACNACNTTYGAYGGN MGNACNCARGTNTCNCAR---------GCNCCNTGGTCNGTNGCNAGYCARAGYMGNGGN CCNYTNAGYACNTAY------GCNACNACNGARCCNCAYTCNMGNAARGGNGCNGTNGCN AARAGYGARGAYGGNTCNAGYGTNGTNTAYGAYCAYGAYGARAARTTYCARCARMGNAAY YTNATGAAYGAYGARMGNGAYMGNMGNMGNGAYMGNGAYMGNATGGCNTCNCARAAYAAY ACNTAYTCNGAYGAYGAYGARGAYCCNGAYAAYTTYAARGARAARATHATHACNCCNMGN GTNAARCCNTCNMGNAAYMGNGAYMGNMGNCCNCCNTCNTTYGARGARGCNACNMGNGCN AGYTCNACNGARMGNTCNTCNTCNGARGARGARGARACNGARGARAGYGAYAAYGAYTCN ACNMGNAARMGNYTNACNACNTCN---------TCNGARGGNGAYGAYGAYAGYGAYGAY TAYACNGARACNGARTCNGARTCNGARAAYAGYTAYGCNAGYAGYTCNMGNMGNGGN--- GGNGCNMGNGCN---AARMGNMGNCCNAARAARGAYGAYAARAARTCNAARTCNAARTCN MGNGCNMGNMGNMGNMGNCARTCNTCNACNGAYGAYGCNTCNTCNMGNAARAAYGGNMGN CCNTCNCAYCARCCNCARCARCARCARCAYCCNATGCCNGCNATGCCNTAYGGNGCNTAY CCNCCNGGNCARTTYGTNCCNGTNATGGCNGGNCAYCCNCCNCARTTYCARCCNGTNCCN ATGATGCCNCCNAAYTAYCCNCCNCCNCARTAYGCNACNGAYCCNTCNCAYYTNCCNCCN ACNTCNCARGGNGTNAARCCNACNGARCCNCCNGTNTAYTCNTAYYTNGTNMGNMGNGGN TAYACNCCNYTNGAYMGNCARAAYTCNCCNTCNGGNAGYGTNGCNTCNAGYCARMGNGCN CCNCCNGTNYTNMGNGAYGARCCNGAYACNCCNYTNCARAGYGGNGTNGARTAYATGMGN MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CARAARACNTCNYTNAARTCNGTNTCNAGYAAR GARAAYMGNTTYAARMGNACNGCNGARGCNYTNCAYAARTCNGGNYTNTGGGAYATHGCN ATGAARACNGGNCAYYTNATHAARMGNAAYCARGARYTNCARAARGARYTNGAYCARTTY AARATGGAYGCNYTNNNNTTYYTNAARTCNGTNATHAARAAYCCNGARAAYMGNGAYTTY ATHAARAGYGTNYTNAAYAGYGCNYTNTCNGCNGGNGCNGCNGARAAYAARAARTCNGTN ATGACNGTNGTNGTNTCNGCNGCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GGNCAY GTNATHCCNAAYAAYAARACNTTYGARCARTTYGCNAGYGCNATHAARTCNYTNGARAAR GARGGNGCNGTNATHTGYGTNCAYTGYACNCAYGGNYTNAAYMGNTCNGGNTAYATGATH TGYMGNTAYATGATHGARGTNYTNAGYATHGARCCNCARTCNGCNATHCAYTGGTTYGAR CARGCNMGNGGNCAYAARATHGARMGNCARAAYTAYATHGAYGAYYTNATGAAYMGNACN CCNGGN------------------------------------------------------ ------------------------------------------CCNCCNTCNYTNTCNGGN AARGTNGTNTCNMGNGTNATHGCNAARGTNGGNAARAAYACNAARYTNYTNTGYCCNGCN AAYTCNGAYCCNTTYYTNACNCARTGGAARAARAAYGGNCARGCNYTNAAYCCNGGNTGG GARMGNTTYAARGTNTCNMGNGARGGNCAYYTNMGNATHMGNGAYGTNCAYYTNTCNGAY GCNGGNYTNTAYACNTGYGTNGCNACNAAYGGNTTYGGNAGYATGAAYATHAAYTAYACN GTNATHGTNYTNGAYGARGARAAYAARGTNTTYCARGARGCNGAYAARYTNATHAARCAR TCNCCNGAYGARGAYATHTAYMGNGARGGNTCNGCNCCNGTNTTYGARGARYTNTCNAAR ATGMGNGARATGATGTCNYTNAARAARCCNATGGGNTCNACNATHMGNYTNGGNTGYMGN GCNAGYGGNAAYCCNCARCCNCARGTNCARTGGTAYAARGGNTCNGARYTNTAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TAYMGN CARTTYTCNTCNGAYYTNCCNGTNATGGCNATGGTNYTNATHATHGCNTTYGCNCCNGGN GGNGCNTTYATHTTYCCNGTNGCNTAYATGTTYCCNMGNTAYYTNYTNTCNCCNCAYTTY TGGACNAARGARCARAARGARGARTTYCARMGNYTNGARATGGTNAARMGNGTNAGYTAY TAYCAYCCNATHATHAARATGATGCAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------CCNYTNCCNGGNCAY CCNGTNGARGAYACNGARTAYYTNGARCCNGTNCARGCNCARGCNTCNTCNAGYAGYTAY MGNGCNAARGCNCCNACNCCNMGNYTNGTNAAYAAYCCNGGNTAYAAYGTNGAYGAY--- ---CCNCCNGARTAYAGYGARACNGAYMGNATGTAYGARGAYGCNATHGCNATHAAYCCN GARYTNGARAAYGCNTAYATHGAY---------------CCNATHGTNACNCCNAARGAR GARGGNGGNTAYGAYACNYTNAAYGCNMGNGCNACNGARACNTAYCARCCNYTNGARGGN ATHGAYGCNGAYGARAARYTNGGNCCNTCNCCNTCNCARMGNACNAARAARGARGAYMGN ACNACNGARTCNGARTAYTTYGARYTNGARATGYTNGARGARGGNAGYTTYACNATGGAR AARAARTCNATHATHMGN------CARTCNCARGCNTCNGGNAAYGGN---ACNGCNACN ACNGARMGNAARTCNGAYTTYACNCCNAAYMGNMGNGGNCAYGGNMGN---MGNTCNGGN TCNGGNGGNGGNGCNAARACNCARGAYGTNAGYCARGCNTCNMGNCCNAGYCCNATHCCN AARTGGGAYMGNACNGTNGGNAAYMGNMGNCARMGNCARMGNAAYGGNTAYGAYTAYMGN CARMGNGARGARGTNGARGARGARCAYGAYATHTTYGAYGTNYTNAGYACNGGNTCNMGN AARGGNAAYYTNAAYCAYYTNYTNAAYTTYAARTTYYTNCCNMGNMGNCARAGYCARYTN GAYGAYAGYMGNTGGCARACNMGNAGYCAYTAYAAYTCNCAYGGNMGNGGNGGNTAYMGN ACNMGNAARMGNTAYAARAARGARCARTTYYTNCARGCNAGYTGYCARTTYGTNGTNMGN GAYACNGGNGAYTAYACNGARCARGCNATHAAYTCNGAYGCNYTNGTNGAYTGGAAYATG ATHGARYTNGTNMGNAGYTTYTCNACNGAYCCNGTNAAYTGYCCNATHTGYYTNGARATG CCNATHGCNGGNAARATHACNAARTGYGGNCAYACNTAYTGYTGGGCNTGYATHYTNCAY TAYYTNAARYTNGGNCARGGNGARGCNMGNAARTGYCCNATHTGYTAYGARACNGTNGAY GTNGAYGAYYTNAARAGYGTNCARTGGATHGAYGTNCCNAAYTTYAARGTNGGNGAYACN ATHGAYATGMGNYTNATGAARAARGCNAARGGNAGYGTNATHACNATGCCNAARGAYCAR TGGGARGAYMGNTTYGGNAARCCNATGAAYATHCARGAYGARGTNAAYACNGARTAYATG AARYTNYTNGTNGCNTCNTCNGAYCARATHMGNGCNGARGTNATHGAYACNGARMGNGTN GCNYTNACNGCNCARYTNGGNAAYGCNGARGARTCNGARGCNTGYTTYATHYTNATGGCN YTNGARTAYYTNGARGTNMGNGARAARACNYTNGARCARGTN------------------ ---------------TTYCARCARACNTCNCARATGAARGAYAARTCNCAYATHCCNGGN YTNTGGTCNAAYGAYGTNGAYAARGCNGARGAR--------------------------- ------------------MGNGGNCCNGAYCCNAARAAYGARACNAAYCCNAAYACNTCN GARATGGCNGTNGGNATG---------------------YTNGARGAYACN--------- ---------------------------------------------------ACNAAYAAR AAYCAYGAYAAYAAYGARAARGAYGARACNACNGAYYTNGARGCNCARGTN--------- ---GAYTCNCAYTCNTCNMGNCARMGNAAYGAYAGYGARMGNTCNYTNCCNTTYGGNTCN CCNCCNAGYCCNTTYCCNCCNATGCCNGAYCARGARGTNAAYCAYGTNCCNYTNAGYYTN GARGARACNGCNGAYCAYYTNGARYTNCCN------YTNGCNGCNGCNAARCARCCNCCN AARTAYTCNCAYAAYYTNAAYGTNAARGAYAAYTAYTAYTTYTAYCARGCNTCNACNGGN CARCARATHTAYYTNAAYTCNYTNAAYGCNCARTGYATGGCNAARGARTAYGGNTCNYTN GARGARAGYCCNAAYATHATHCARGGNACNATHGTNGCNATHGARMGNATHTTYATGACN GARGAYGTNMGNAARMGNYTNMGNTAYYTNGAYCAYATHCCNYTNACNTGYGARGTNCAY ATHGTNGARYTNAARYTNAARCCNCCNATHGTNAGYAARGARACNYTNAARTAYTTYGAR GCNTCNTTYGARMGNAARMGNAARCARMGNCARCARAARGARMGNGARGAYAARMGNMGN GCNAARAARATHGARATHGARCAYAARAARAGYYTNGGNATHTAYCCNGARGTNCARATH CCNYTNGAYTGYYTNGARCAYTTYCCNTCNCAYYTNTCNGCNAGY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYGTNGCNACNCCNYTNTTYGGNCARYTNCARAARTTYCARTCN AAYGGNGCNCCNGARATGATHACNTTY---TCNGAYAAYCCNTTYGARTCNCAYACNCAR CAYTCNCAYGTNAAYTCNTCNAARCCNTCNMGNATGYTNAARYTNGARYTNACNGAYGGN GCNMGNACNGTNCAYGCNATHGARTAYMGNTCNATHCCNTCNYTNCAYACNGAYYTNCCN GCNGGNACNAARGTNGTNATHAARGGNCAYGTNYTNTGYMGNMGNCARGTNYTNYTNYTN CARGARGAYAAYGTNTGYGTNGTNGGNGGNGARGTNGAYGAYYTNATHGTNGTNAAYAAY CCNATHATHAAYYTNCARGCNGARATG--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNACNYTNYTNGAYYTN CCNTGGGARCARGTNYTNTGYMGNAAYATHYTNCCNCAYYTNAGYATHCCNCARYTNTTY CARYTNMGNGCNGTNAGYCAYGAYGCNYTNTAYYTNGTNGAYACNTAYTTYAGYYTNCAR TTYCAYYTNAAYATHTGYCAYYTNGGNAARAARYTNACNTCNACNGCNTTYTCNYTNATG ACNGGNGARAGYCAYTGYYTNAARACNYTNTTYYTNMGNGGNGCNAARTAYGCNYTNACN AAYGARGTNTTYYTNCCNGTNYTNTCNAAYAAYTCNMGNYTNGARAARATHGAYATHAGY GGNTGYACNGCNYTNTCNGGNTGYGTNYTNTAYGCNATHGGNATHAAYTGYCCNAARYTN AARCARYTNATHGTNMGNGAYTGYGTNACNTTYATGGARGARAAYTTYYTNTCNTTYYTN TGYGTNAARCARCCNGTNAAYYTNGARTAYYTNGAYGTNTCNGGNTGYTGGAAYYTNGGN GAYGAYYTNATHATHAARYTNGTNCARMGNTGYCCNAAYYTNAARCAYYTNYTNYTNGGN AAYYTNTAYGGNYTNACNGAYMGNACNGTNTGYGCNATHGCNCAYTCNTGYCCNGGNYTN GTNGCNYTNAGYATHGTNGGNTGYTGGMGNATHACNGAYCAYTCNATHAGYYTNGTNGCN GCNTAYTGYCCNAAYYTNAARYTNYTNGARGTNAARGAYTGYMGNGAYATHACNGARGAR AGYYTNGARCCNYTNMGNAARMGNCARGTNACNATHGAYAARCCNGGNCCNCCNTCNTCN TAYATHAAYMGNYTNGARTTYYTNAAYAARGCNCAYMGNATHAAYGTNATGYTNGAYAAR GTNGTNYTNTAYAGYTAYTTYMGNAGYTCNTGYAGYTGGMGNGTNMGNATHGCNYTNGCN YTNAARAARATHCCNTAYGAYTAYGARGCNGTNCAYYTNYTNAARGGNCAYCARMGNACN GAYGARTAYAARYTNYTNAAYTCNTCNGGNTAYATHCCNACNYTNAARATHGAYGGNYTN ACNYTNACNCARTCNYTNCCNATHATHGARTAYYTNGAYGARMGNAAYCCNGARCCNGCN YTNYTNCCNAARGAYAARGCNGAYAARGCNCARGTNMGNGCNATHGCNGARATHATHAAY AGYGGNATHCARCCNYTNCARAAYYTNAARGTNYTNCARAARGTNGGNGARACNAARATG GARTGGGCNAAYCAYTTYGTNACNGCNGGNATGGARGCNYTNGARCCNGTNYTNGARAAR ACNGCNGGNACNTAYTGYTTYGGNGAYGARGTNACNATHGCNGAYYTNTGYYTNGTNCCN CARGTNGCNAGYGCN---GCNMGNTTYAAYGTNGAYATGTCNTGYTTYCCNACNATHTCN MGNGTNAAYAARACNYTNGARGARYTNCCNGCNTTYAARGTNGCNGAYGCNMGNMGNCAR CCNGAYACNCCNGAYGAYYTNMGNATHGARATGGARAGYGCNGAYGGNGCNGTNYTNTCN YTNTGYAARGAYGTNTGGAARTGGMGNATHTCNGARAGYCCNGARATGGCNACNTTYTGY GGNTTYTAYCARGAYGAYGAYAARTGGGAYGAYATHAGYGARGARGCNTAYGTNMGNMGN GARTCNAARGTNMGNGARTTYYTNAARGCNGCNGARGCNYTNGAYGTNYTNAARTGYAGY CCNGAYGTNGCNYTNAGYTAYMGNYTNYTNYTNTGYGAYYTNAAYACNTTYATHAARGGN GTNTCNTTYAARAGYTAYTTYYTNCCNYTNAAYTAYYTNGARGGNATHCAYACNGAYTGY AAYYTNACNGTNGCNTAYATGAARTTYGARTCNGARAARGAYTTYCARAAYYTNAARACN MGNYTNGARAARYTNCCNTCNMGNGTNGCNCARGTNATHGCNATGYTNAARAARGGNATH AARCARGGNATHGTNAAYCCNAARCAYTCNATGCARGAYATHCCNGGNCARATHGAYATH ATHYTNGCNACNCCNGCNGARGAYTGGGGNYTNATGAARCCNTTYAARGARAAYAARTGY GGNYTNGAYTCNGARGTNTTYCARAARYTNAARACNCARTGYTGYGAYGTNATHCARTCN YTNYTNATHCCNGCNTTYAAYGAYYTNAARACNTTYGTNGTNGARACNTAYATGAARAAY GTNMGNCCNAARGARGGNGTNAAYAGYYTNCCNGAYGGNGAYAAYTGGTAYCARAGYTGY YTNAAYTTYCAYYTNACNTGYTCNATGACNCCNCARGARGTNCAYGAYYTNGGNYTNAAR GARGTNGCNMGNATHAAYTCNCARATHGTNGCNYTNGCNAARAARGARGGNYTNCCNGAR ACNATGCCNGARYTNYTNGARGCNATHGARAARAARCARGCNAAYTCNTTYMGNTCNCAR GAYGARGTNYTNAARTAYGTNCARGAYYTNTGYGARAARAARATHMGNCCNAARATHAGY GARTAYTTYAARGAYYTNCCNGAYATHCARATGAARATHCARYTNACNCCNGCNTAYAAY GCNTCNGCNCCNGCNGGNTAYTAYYTNAAYGGNACNCCNGAYGGNTCNMGNGAYGGNTCN TAYTTYATHAAYGCNAAYAAYYTNGARTCNTGYATHCCNTAYTCNYTNCCNGCNYTNTCN YTNCAYGARGGNGARCCNGGNCAYCAYYTNCARGGNATHTAYTCNYTNGCNGCNACNCAY YTNCCNGAYTTYMGNMGNTAYTCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGTCNGAYAARYTNAGYACNMGNGTNATHCARGTNACNAAY ATHGCNCCNAGYTGYACNAARGAYCARYTNMGNACNYTNTTYGGNTAYYTNGGNMGNGTN AARGARYTNGARATGTAYCCNCCNGAYGGNGCNGAY---GGNGTNGTNACNGCNMGNGTN GCNTAYATHGARTTYGARGAYTCNACNACNACNGGNGTNTCNYTNCAYYTNAGYAGYACN GTNTTYATHGAYMGNGCNATHATGATHGTNCCNGTNATGGAYGGNAARATHCCNGAYGAR AGYTCNGCNYTNCARYTNACNCCNTCNGCNGTNGCNGGNATGYTNCCNGGNCARCCNACN TGGCCNGCNAAYGTNGTNTCNCARGTNACNGGNYTNGGNGCNAAYCARATHATHATGACN AAYGAYCCNMGNYTNACNTCNYTNGGNYTNCCNCARTAYCCNCCNYTNCCNGCNACNACN GAYCCNAGYAARATHGARGARATHMGNMGNACNGTNTTYATHTCNGAYYTNGAYGCNAAR GTNACNCCNGARATGYTNYTNTCNTTYTTYTCNCARACNGGNGARATHAARTAYATHMGN ATGGCNGGNGAYGARAAYGCNCCNACNMGNAGYGCNTAYATHGARTTYACNGAYCARMGN TGYATHGCNCARGCNYTNAGYTAYAAYAAYGTNGTNTTYCAYGGNMGNACNGTNAGYGTN AARCAYGCNACNACNAGYATHGTNAARCCNACNCCNMGNTCNGARGCNTCNCARMGNGAR ATHGAYGAYGCNATGAARAARGTNAARGARGCNTCNAARYTNATHTCNGCNGCNGCNAAY AGYGAYMGNGARAGYTCNMGNTCNCCNGCNMGNAARMGNTCNMGNTCNAARGGNMGNAGY MGNTCNMGNTCNMGNTCNMGN---MGNMGNTCNMGNTCNMGNTCN---CCNMGNMGNMGN MGNMGNAGYGGNTCNMGNTCNMGNMGNMGNTCNMGNTCNMGNMGNMGNTCNCCNAARMGN TCNMGNACNCCNGTNMGNMGNMGNMGNTCNMGNTCNMGNGGNGGNGTNCCNCARCCNGCN CCNCCNGTN---MGNTCNMGNACNMGNGAYMGNMGNMGNTCNMGNACNMGNTCNCCNGTN MGNMGNMGNMGNTCNMGNTCNMGNTCNAARTCN------MGNMGNTCNMGNACNCCNCCN AARTCNTAYAGYAGYMGNMGNMGNTCNCAYTCNMGNGGNMGNMGNAGYMGNTCNMGNGAY MGNMGNGAYAARMGNGARMGNAARAARAGYMGNTCNATGTCNCCNCCNACNYTNGTNMGN GARGGNTCNGCNTCNCAYGARGARGAYMGNGARAARTCNCCNYTNAARGGNAAYGTNMGN ACNCCNAGYCCNCCNMGNGCNAARAARMGNAGYYTNACNCCNAARMGNMGNAGYMGNTCN MGNTCNCCNAAYMGNMGN---AARAARMGNCAYCAYTCNMGNTCNCCNTCN---MGNAAR MGNTCNMGNTCNMGNAGYGGNTCNMGNTAYMGNTCNMGNMGNGAYMGNAARMGNAGYMGN AGYMGNGAYMGNAARCAYGAY---AGYAARAARAARATHAGYMGNGAYAARGAYGAYMGN AARAARGAR------GGNAGYTCNAARATHAARMGNGAYTAYGAYGARGARGARAARGGN TTYGCNAGY------------GAYMGNAGYGAYGGNAAYAGYGAYGGNATHYTNTCNMGN GGNGARTCNCCNAGYCARCCNCCNYTNYTNGARAARGAYACNGAYAAYCARCCNGTNGAY ATGGAYATGAGYGAY--------------------------------------------- ------------------------------------------------------------ ---------------------------GGNYTNYTNAAYYTNCARTGGYTNGCNGAYCAR ACNGCNAAYGCNAARGCNTTYGAYTTYGCNATHGAYGARMGNTCNGTNTCNACNCARMGN CCNGAYGGNAAYYTNCARACNACNYTNACNGCNACNMGNACNGTNGTNYTNCCNGGNGTN TCNGARGARGGNGARGAYATHCARAAYGGN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GTNAARGTNGGNGAYTTYGGNYTNGCNMGNATHGTNYTNMGNGAY AAYGARTAYCAYATGTCNGARAARTCNAARTTYCCNTTYAARTGGTCNCCNCCNGARGTN YTNCAYTAYMGNMGNTAYACNAAYAARTCNGAYATHTGGTCNTAYGGNATHYTNYTNTGG GARATHTAYACNTTYGGNGARATGCCNTAYCARGGNYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGATHCAYTCNATH ATHTTYYTNTCNTCNYTNYTNTTYATHGGNACNTGYCAYYTNTGYATGATHAGYCCNCCN CARMGNGGNTCNATGGTNGGNATHAAYAARCCNGCNGCNAGYGAYTGYATHYTNYTNCAR GCNCCNTGYGGNGGNMGNAGYGGNGGNGGNCCNATHYTNGARYTNATHGCNGGNCARAAY TTYACNGTNACNYTNATGAARAAYYTNGAYCAYTTYAAYATGGCNGCNCCNGGNAAYTTY ACNATHTCNATHGGNMGNGGNGAYGGNCAYTTYAARCARYTNYTNTCNTTYCCNGAYAAY GCNGAYCCNTCNYTNACNYTNTAYTCNTAYAAYGTNACNATGCCNAARGARCAYGGNGAR ATGGTNYTNCARTCNGTNTAYAAYACNAAYAAYCCNAARGCNCCNCCNGCNTTYCAYCAR TGYAGYGAYYTNMGNYTNGTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARATHTCNCAY ATGATHGCNTTYATHGAYCARGARGCNTCNGARAARGTNGARGARATHGAYYTNAARGCN GARGARGARTTYAAYATHGARAARGGNMGNYTNGTNCARCARTCNMGNGTNCARATHATH GAYTTYTAYGAYAARAARGTNAARAAYGTNGARYTNCARAARAARATHCARAAYTCNAAY ATGCARAAYAAYGCNMGNYTNGARATHYTNNNNAARAARGARGARTAYGTNAARGARGTN YTNGAYGARGCNMGNGARCARYTNAARAARGTNGCNAARGARAAYCCNGARGARTAYAAR MGNYTNYTNYTNMGNYTNATHATGCARGCNYTNGCNMGNYTNATHGARTCNAARGTNACN ATHMGNTGYAARMGNGARGAYGTNCARATGATHAARAAYTCNATHCCNAGYYTNGTNAAR GARTAYAARGARYTNYTNAARGGNAARTAYGCNYTNGAYYTNGTNGTNGAYGARGARAAR TTYYTNTCNCARGARATHTGYGGNGGNGTNGARYTNCAYGCNYTNAGYGGNAARATHGTN GTNGTNAAYACNYTNGAYGARMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNCARMGNGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGCNGARAGYGAYCARCARTAYACNATHTAYGAYGCN---AAYCARCCNYTNACNYTN ACNGTNAGYAAYGTNAAYCARGGNACNGARGARGCNCARGCNGTNCARAGYATHCARTAY ATHTCNTCNGAYGGNGTNCCNGTNACNCAYYTNGAYTCNAGYGAYGTNATHCARGTNGCN CARGCNGCNGAYGGNAGYTTYCARCARGCNACNTCNGGNTTYCARAAYATHCARGGNTCN GTNCARCCNCARGTNATHACNAAYGCNGCNTCNGTNCCNATGTCNGCNAAYTCNCARCAR GGNGGNACNATHYTNCARTCNAAYAGYGTNYTNMGNAAYGTNACNCARCARCARACNCCN CARGCNTCNCARCARCARACNATHCARACNGCNGGNACNTCNACNCCNTCNGTNGGNACN TCNGCNACNGGNATHCCNCARATGYTNTTYYTNAAYCARGTNACNATHAAYGGNCARACN TCNTTYGTNYTNGTNGAYGCNAAYAAYAARCCNATHCARYTNCCNCARGGNATHCARGTN ATHAAYYTNCCNCAYCARCARYTNTCNGGNCARTCNATHCARATGCCNGGNGGNGAYACN GGNGAYGARCCNYTNTAYGTNAAYGCNAARCARTAYCAYMGNATHYTNAARMGNMGNCAR GCNMGNGCNAARYTNGARTCNGARGGNAARATHCCNAARGARMGNCARAARTAYYTNTAY GARTCNMGNCAYAARCAYGCNYTNAAYMGNGCNMGNGGNTCNGGNGGNATHTTYGTNGGN CAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATHMGNGARAAYGGNATGTAYGTNTAYGARCCNTTYATGGARACNGGNGGNYTNGAYATH AARGTNTAYGCNGTNGGNGARACNTAYGCNCAYGCNGARGTNMGNAARGCNCCNGCNGTN GAYGGNMGNGTNGARMGNGAYGCNAAYGGNAARGARGTNMGNCARACNATHGARYTNACN GARGARGARAARAAYATGTCNMGNATGGTNGTNMGNGCNTTYAARCARAGYGTNTGYGGN TTYGAYATHYTNMGNACNGAYGGNCAYTCNATGGTNTGYGAYGTNAAYGGNTTYTCNTTY GTNAARGGNAAYAARGARTAYTTYGAYAAYGCNGCNATGAAYYTNTCNAARATGYTNGTN AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARYTNACNCAYGCNAAY YTNCARGCNGARAGYATHAARTCNGTNATGGGNAARAARCAYAARTAYGGNAARCAYTCN TCNTCNTCNTCNTCNTCNTCNTCNAGYAGYGAYTCNTCNGAYGARGARTGGMGNCAYYTN CCNAARCAYGARAARAARATGMGNAARAARTGGAARAARCARATGMGNAARGGNCAYGTN GCNCAYGGNACNYTNCCNCCNTGGCARGGNGGNCCNGCNTGGGCNCCNCCNATGAARGCN GGNAARGGNCAYAARAARGGNGCNAARGGNTAYCCNATGGGNACNCARCCNCCNACNGGN TAYCCNGTNGGN------GGNTAYCCNGCNCCNCAR------------------------ ---------------GGNTAYCCNACNCARCCNGGNTAYCCNGGNCARCARCCNGGNGCN TAYCCNGTNCCNCARAAYCCN------GGNTAYCCNCCNCCNGGNGGNGCNTAYCCNGGN GCNCCNCCNCCNGGNGGNTAYCCNGCNGGN------------GGNCARTAYCCN------ ---CCNCCNCCNCCNGCNCARTAYGCNCCNGCNACNGGNGCNGCNTAYGGNGCNCAYGGN GCNCCNTCNGGNCCNTTYCARGCNCCNCCNGGNGGNGCNTAY---CARTCN------GGN TAYCCNCCNCAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ACNYTNTCNCARMGNGCNGARGTNYTNCARGCNGARYTNCARAGYATH GARGAYAARACNAARGCNATHCAYGARGARAARTCNAGYGCNGARGTNAARYTNMGNGAY AAYYTNGARMGNYTNGAYCARYTNGARTTYGARAARACNATGATHTCNGARCAYGCNTCN GARYTNCARGGNACNATHCARGAYYTNGTNTCNCARAARGARATGACNGARAARGARYTN AARGARGARATHMGNGCNMGNATHTCNGCNGARGAYMGNYTNAARGARGCNGARMGNTCN YTNAAYTCNYTNGAYCAYGCNGTNGARACNCARTCNCAYMGNATHGARGARGARGCNAAR GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------YTNYTNGGNGTNGGNCAR TCNYTNACNGCNGTNYTNYTNTTYMGNGGNYTNGAYGGNTTY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GAYGGNMGNMGN TCNGARCCNAAYTTYGGNMGNTTYTAYAAYACNAGYTAYYTNGGNYTNAAYGCNGGNAAR GCNTAYATGAAYMGNGCNAGYYTNAAYGCNAAYGAYAARAARGAYGGNAARACNGGNAGY CAYTTYCAYMGNCCNCCNAAYTTYACNTAYGCNAARGARCCNCCNTCNTTYYTNAARAAR AARGGNACNGGNATGTCNGCNYTNACNTCNGTNCARMGNGTNGTNAARGTNMGNMGNAGY TCNTCNCCNGCNGAYGTNMGNAAYCARGARGCNGTNMGNATGAGYATGTTYCCNAGYGCN AARCCNAARMGNCCNGAYGARCCNGAYAARATHGARMGNGAYGAYTGGCCNGGNCCNGCN TCNCCNGCNGCNATHYTNCCNGARYTNYTNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNAGYYTNGGNGGNAGY AARAARATGGARGTNAARACNGTNGARACNATHGAYGAYGARTAYTCNCCNGGNGTNTTY YTNYTNACNAAYTGGYTNACNAAYCCNTCNGAYAAYTCNMGNTCNGGNTTYGTNCARTGG AARCCNGTNTCNTAYYTNGGNGARACNMGNGGNMGNAARACNGTNACNAARGTNAARCAY TAYGAYYTNYTNTCNGCNGAYMGNGCNGAYACNYTNAAYGCNACNYTNYTNTCNGCNYTN TTYGGNGAYGAYYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHAARGTNYTNGARTTYGTNYTNGCNATHTTYGCNTTYGCN ACNACNACNAGYCCNGAYACNTCNACNACNTTYACNGTN---AARGAYTGYGGNATHTGG AAYAAYAAR---ACNGGNCCNGTNTCNAARACNTTYTCNTAYAGYTAYCCNTAYGAYYTN GARGARACNTGYTTYAARYTNCCNYTNTGYACNCARGTN---CARCCN---------GGN GARTTYTGYYTNYTNGARGGNTCNAARTCNTCNGCNCARTTYTAYGTNTTYGTNGGNGTN ATHGTNTTYYTNTAYTGYYTNGGNGCNATHGTNYTNTAYGTNTTYTTYGAYGARYTNTAY MGNMGNAAYACNMGNATHGTNYTNGCNGAYTTYATHGTNTCNTGYGTNYTNACNYTNTTY TGGATHATHTCNTCNTCNGCNTGGGCNGCNGGNYTNGAYGAYGTNAARYTNTAYACNGAY CCNTAYGAYGGNGGNATHTTYCARAARAAYGTNYTNGARTGYCARGARAARGGNGCN--- TGYGTNACNGAYAARGARGGNAAYTTYGCNAGYYTNAAYGTNTCNATHATHTTYGGNTTY YTNAAYTTYGTNGTNTGGYTNGGNAAYYTNTGGTTYYTNTAYAARGARACNCCNTGGTTY AARGTNCARGCNAARCCNCCNACNCARCCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CAYCAYCAYCAYCAYCAYMGNCCNCCNCCNCAYCAYYTNGAYCCN CAY------AGYMGNCAYGAYMGNGTNGGNGAYGGNCAYYTNCCNCAYCAYGAYTCNTCN GGNYTNGAYGCNGCNAARMGNAARACNYTNCCNYTNTGGYTNMGNGARGGNYTNGARAAR ATGGARMGNGARAARCARAARCARYTNGARAARGARCARYTNAARAARAARCARAARGAR ATGTAYGCNATGCARGARGAYGGNTTYAARGGNAARGGNGARGARGARGARGARGAYGAY GAYGGNCARCCNAARGTNCCNMGNAARAGYMGNTTYGAYTCNGAYGAYGARGAY------ ---GARAAYAARAARGAYGARGAYGARGAYGCNGCNGAYAAYAGYGAYGAYGGNGARCCN MGNCARAAR---CARCARCCNGARCARTCNAAR------------TCNTCNCCNGGNAAR MGNAGYCCNTCNCCNACNGARTAYATGACNGARGARGARMGNGARYTNGCNYTNATGATG AARGTNAARMGNYTNYTNACNGARACNYTNYTNGARGTNACNGAYCARGARATHMGNAGY ATHGCNACNGAYGTNTAYCARMGNGARAARAARAARGCNCARAARGCNCCNGCNAARCAR YTNGCNAARTCNTCNGCNYTNGCNTCNYTNTCNAGYYTNGGNYTNGGNTAYGGNTCNGGN TCNGAY---------AGYGARGARGAYGARAARGAYGARATGGAYTCNGAYAGYGAYYTN GAYGARACNATHMGNMGNAARAARGCNGARTTYGCNAARAARCARAARATHTTYTCNGAY TCNGAYGAYGAYGAYGTNAARTCNACNGGNMGNGAYAGYAARAGYMGNAGYGTNAARGAY GARGARAARTTYGAYAARTCNMGNGAYMGNGAYGAYMGNMGNCARACNGAYAARCAYGAR YTNAARACNGAYMGNMGNGAYAGYAARGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTAYAAYGGNATHGGNYTNCARACN CCNMGNGGNAGYGGNACNAAYGGNTAYGTNCARMGNAAYYTNGCNTTYGTNAARTCNAAR AARGAYMGNATGGAYTAYAARGAYGARGAYGARYTNAARAARYTNGARCARTCNATGAAY AARCARCCNAAYCARGARATHYTNGAYCAYGARMGNAARMGNAARGTNGARYTNAARTGY ATGGARATGCARGARYTNATGGARGARCARGGNTAYACNACNAARGARGTNATGGAYAAR GTNAAYATGTTYMGNAARATGYTNATGGCNAARGARGGNGTNTCNGAYCCNTCN---ATH GARAARGAYGARCAYGGNMGNCCNATHGCNAARGARACNCAYCARYTNGCNGARGCNAAY CARATHAARAAYGAYAARYTNAARGARGCNTTYGGNYTNTCNGAYTAYACNGAYGGNAGY GCNTTYGAYCCNGAYMGNAARGCNAARGARGARCARGCNAARGCNGTNGCNYTNGCNCAR AARAARTAYAGYATHGTNAAYAGYTCNGARGARGAYGARGAYAAR---GARAGYTCNCCN GCNMGNAARAARAARAARAARAARTCNMGNCAY---GAYGGNTCNTCNCCNGARMGNAGY AARGARAARMGNAARMGNAGYMGNAARCAYAGYAARMGNGAYMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNTAYCARMGNYTNYTNTCNGGNCAYATH GTNATHCCNACNAARGAYMGNGGNTTYAAYCARTTYTCNTGGYTNGAYYTNACNGARGTN GTNTTYGARCARGTNACNGCNYTNATHGAYATGGTNCAYACNTCNGAYGARAARYTNAAR CAYAAYTAYGCNTCNTCNAARAAYCARGARGARGCNTTYGCNTCNYTNAARCARGGNCAY GARGARCARATHACNAARYTNACNAAYATGGCNMGNGARMGNGARTCNGCNTGGCARMGN CARAARGARGARYTNGARCARCAYTAYAAYGARATGATHTCNGAYYTNCARTCNCARTCN AARAARAAYCARGCNATHGCNGAYCARGCNTGGGARAARGTNMGNGCNACNGGNAGYGTN CARCARGGNYTNGARTCNGARGTNGTNGARYTNMGNMGNGARYTNGCNGARTCNCARGTN CARGCNTCNTCNYTNYTNTCNGCNTGYGCNYTNYTNAGYGGNGCNYTNTAYCCNYTNTAY ACNAARGCNGCNATGYTNTCNTCNCARMGNCAYATHYTNGARGARYTNTTYTGYAAYTGG GARAAYTGYMGNGAYMGNGCNATGTAYYTNTGYTCNGTNYTNAGYTCNGGNMGNGARAGY GARCARGAYCARCCNGARMGNGAYAAYMGNTTYCARMGNAARMGNAGYCCNATHYTNMGN TTYMGNATGGGNGTNATHGCNGTNYTNGCNGCNAAYMGNYTNGCNTAYYTNGGNTCNTGY TGYAARAARTGYTTYATHACNTAYAAYTCNACNGTNAAYCARAAYGGNYTNACNGTNTCN ACNGGNGARGGNMGNYTNACNGCNGTNAAYTCNAGYATHTGYTAYGARCCNAAYGARCCN GCNACNGGNTTYGGNCCNTTYTCNCARGCNGARAARAARYTNGGNGCNTGGYTNACNAGY TCNGARYTNYTNGARACNGTNATGGTNTCNATGACNGARYTNCARGARTCNYTNMGNATH AAYMGNAAYCARGAYAAYCCNACNGARGTNAARYTNGTNYTNAAYGCNGCNMGNACNTCN TTYACNAARTAYGTNGAYMGNYTNGCNYTNTTYTTYCCNGCNTCNTCNYTNCCNGTNCAY TCNTCNGTNMGNGARMGNACNTCNYTNYTNMGNAARYTNGARMGNCCNYTNTCNCAYCAY YTNMGNAAYATHTCNTTYACNTCNAARGGNAGYYTNATHTCNTCNCARGARGTNATGAGY AGYYTNCARAAYCAYATHYTNGAYYTNACNCARMGNYTNCAYTCNGCNGARAARGARMGN MGNCAYYTNYTNTCNGAYYTNAAYGARYTNAARCARCARATHGGNGAYGARAAYATGTCN YTNCARAAYTCNTCNGAYAARCARTCNTCNAAYAARGGNACNAARTAYGTNGCNATGGAY AARTTYGARAARGTNTGYGTNGARYTNTCNGGNGCNYTNMGNMGNGARCARAARGCNCAR GTNYTNYTNCARGARCARAGYAAYCARYTNTCNGARYTNACNTCNMGNYTNGAYATGTGY GCNTCNGARGGNGTNCAYAARGARAARAGYYTNGTNAAYATHCARGARGGNYTNACNGAR ATGCARAGYCAYATGMGNCAYAARGAYCARAAYYTNMGNCARATHAGYAARCARYTNGCN CAYACNGARTAYGARMGNGAYACNYTNCARAGYAAYYTNAARGAYGCNGARAAYGCNYTN MGNACNGCNGCNMGNGAYAARGARATHYTNGCNCARTAYATHAARAAYGTNGGNAGYGCN YTNGARACNGCNAARAARCARTTYYTNATHATHAGYGARCCNYTNCCNYTNTCNAAYGAY ATGTCNYTNTCNMGNYTNYTNYTNGAYGCNGAYYTNATHCCNATGGAYATHGGNAARACN GGNCCNGARYTNATHTCNYTNCARAAYYTNGTNGGNGGNTTYGTNGAYGCNCARCAYCAR GCNGTNAAYAARATHMGNTCNYTNGAYGARGARATHGCNTCNCAYMGNAAYCAYATHGAR TCNYTNAARMGNGARYTNAGYAAYGCNGTNCARMGNGARTTYAAYCARCARYTNGARTCN GCNACNGAYGGNGCNTAYTCNGTNYTNACNGAYCARGARGARGAYATHGTNCARYTNAAR CCNGAYTCNGAYAAYTCNTAYGARAGYYTNCCNACNCCNMGNAARYTNACNCCNCCNATG TCNACNAGYYTNAGYAAYCCNTCNATHAARCAYAARAARTCNGCNTTYCAYTCNGTNAAR TCNAGYAGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CARCCNCARACNACNACN GARGAYAAYCCNTTYGCNAAYGCNGAYATHATHCAYGAYTTYCAYGARTAYTAYAARTCN AARGCNGTNAARGAYAGYGTNGAYAAYCAYTAY---GTNGARYTNGCNACNGCNGARAAR CAYCARTCNYTNTCNGAYAAYCAYMGNGTNGCNGCNGTNATHCCNYTNAARTTYCAYTTY CCNTTYTAYGGNCAYYTNGTNAAYAAYGTNACNGTNGCNACNGGNGGNTTYATHTAYATG AGYCCNTTYYTNCAYCARTGGYTNACNGCNACNCARTAYATHGCNCCNYTNATGGCNAAY TTYGAYCCNTCNYTNAGYACNACNTCNAAYATHTAYTAYYTNAGYGARGARGAYAARTTY ACNGTNGARTGGAARGAYGTNMGNYTNCARGAYCARAARGAYGTNGGNYTNTTYACNTTY CARACNTCNYTNCAYATHAAYGGNTCNATHAGYTTYGTNTAYAARGAYATHCCNATHGAY GCNAAYAARATHTCNGAYGARGARCAYCCNGTNAARATHGGNYTNTCNGAYGCNTAYTAY AAYGAYACNTAYATHAARMGNTTYGGNATHMGNMGNMGNACNATHTAYGARTAYCAYCAR YTNACNYTNAARMGNAGYYTNGTNMGNACNGGNGCNGTNATHTTYATHAAYCCNYTNCCN ACNTGYAAYYTNYTNACNGAYTGYCAYTCNTGYACNAAYCAYACNGAYGTNGAYTTYGAY TGYAARTGGTGYAAYATHATHGGNMGNTGYTCNGAYGGNYTNGAYTGGTAYMGNCARCAY TGGGAYAARTAYGAYTGYAAYAARGTNACNAARAAYCARACNAARGARTGYATHGGNYTN CCNCCNCCNYTNAARCCNATHATHCAYCCNATH---ACNCCNYTNAARGCNCCNAARAAR TGYGARGGNGGNGGNTGYGGNAARGGNAARGAYGCNCCNGTNGCNGTNATHGTNGTN--- GTNYTNYTNYTNGTNYTNGCNYTNATHGGNGGNGTNGCNGGNTGGGCNTAYTAYGCNTAY ACNCAYCCNAAYTCNAARTCNGGNATGTGGYTNATHCARCAYMGNCCNAGYCARATHAAR GCNAARATHCARTTYTGGAARAGYAGYTCNGAYAGYGGNGCNAARTAYMGNACNGARACN GAYGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TGYCCN TCNYTNGCNGGNAARCCNAARYTNTTYTTYYTNGTNTCNTGYYTNGGNYTNAARTAYTCN AARGCNGTNCCNAGYTCNYTNCAYGARACNGAYTCNGGNATHCARACNAAYAGYTTYGTN TGYAAYGAYCARGAYTTYYTNATHGGNTAYAGYACNGTNATHGGNAAYGTNGGNTTYMGN GAYACNCAYAARGGNACNTGGTAYATHACNGCNYTNACNGAYATHYTNACNCARTAYCAY ACNMGNGARAGYYTNCARCAYATGYTNGTNGCNGTNAAYCAYMGNGTNGCNACNAAYAAR CAYAGYTGYGTNGAYGARCARGGNAARCAYGGNGAYTAYACNCARGTNCCNGCNCCNCAR CAYACNYTNACN------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN GTNTCNGGNGGNYTNGTNAAYGARMGNTCNYTNMGNGAYTCNAARGGNGARTTYCAYAGY ACNCAYCAYTCNTGYATHATHTCNGCNYTNGCNYTNTGYGGN---GAYGTNCARGTNGCN TCNATHYTNYTNMGNAGYCAYATHCARYTNGARGAYGARGTNAARMGNGTNATHMGNGGN YTNATHGAYTAYAAYTTYCCNTAYGARAAYAGYTTYGCNYTNATGTAYGCNTGYGTNGGN MGNGGNCARCAYYTNTAYAAYAARGARAAYGTNGARGCNGAYATHTTYMGNAARTAYTTY CCNAARACNCCNYTNYTNGGNTTYTTYGGNAAYGGNGARATHGGNTGYACNTTYCCNCAR CCNGGNYTNATGCCNGCNACNAAR---------TCNCCNAARCCNGAYCCNAARGTNGTN MGNGGNGCNGARGARYTNACNCCNGTNCARYTNAARMGNCAYATHGCNGAYATGMGNGTN AARYTNGAYGARTAYMGNAAYACNCAYGTNCCNAARATHATHCAYTCNTAYACNACNTGY ATHTGYYTNATHTCNYTNCCNGAYYTNMGNAARAARMGNGCNGARGTNTCNAAYTGGYTN TCNCARGTNYTNAARCAYGARCCNATHCCNGAYTTYGARGTNAAYGCNGARACNATHCAR YTNYTNCAYMGNYTNTCNATHATHAGYCARCAYAAYGARAARAAYTCNCARYTNTAYGTN GARGAYYTNAARAARAARTCNGARGARTAYAAYGCNGAYGCNCARMGNATHGCNGGNATH YTNGARMGNYTNACNYTNGGNCARAAYTGYYTNTCNMGNTCNGGNTCNTCNTGYGTNCAY GCNYTNGCNMGNACNGGNGCNTCNYTNTGYGTNAARAAYGCNTCNGAYACNTGYTTYATG YTNTCNYTNMGNGARYTNCARTCNAAYATHAAYGARGTNAARGARMGNYTNGARATGGAR GARCARGAYATGCARMGNYTNTCNAARAARACNCARGGNGTNYTNYTNAAYCAYAGYTCN YTNCARAARGCNYTNGAYATHYTNGARAARMGNGCNGCNGGNGARACNGCNAARATHGCN GARMGNAARAARGARATHGCNATHYTNAARAARGCNACNGCNGARAAYGARACNATHGTN GARAARYTNAARACNMGNATHGCNAARTCNGGNGTNAGYGARACNGAYTTYCAYGAYAAR YTNGTNAARAARAARGARAARYTNGAYGCNGTNGAYAGYGARYTNGCNCCNYTNAARTCN GARYTNAARTCNTTYACNAGYYTNCCNCCNGAYGCNATHGARGCNAARGTNAARATHGAR CARYTNAARMGNGARYTNAGYMGNYTNCARACNCARATGTCNGARTGYGTNGAYGTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------AARAARAARAARAARAARAARAARTGGYTNTGY ATHTGYYTNACNAAYTGYAARTAYGAYGTNGTNMGNMGNACNTCNMGNAARTTYGGNTTY AARGARGTNCCNGAYGAYGAYGAYTGGACNYTNTAYTGGACNGAYTTYTCNGTNGCNYTN GARMGNGTNATGGARATGAARAAYTAYCARAARATHAAYCAYTTYCCNGGNATGAAYGAR ATHTGYMGNAARGAYATGYTNGCNMGNAAYYTNAAYMGNATGCARAARATGTTYCCNAAR GARTAYAAYGTNTTYCCNAARACNTGGTGYYTNCCNGCNGAYTAYGGNGAYTTYCARGCN TAYACNMGNCARAARAARAAYAARACNTAYATHYTNAARCCNGARTCNGGNTGYCARGGN AARGGNATHTGGGTNACNAARAAYCCNAARGARGTNAARCCNCAYGARCAYATGATHTGY CARGTNTAYATGAAYAARCCNTTYYTNATHGAYGGNTTYAARTTYGAYYTNMGNATHTAY ACNYTNGTNACNTCNTGYGAYCCNYTNMGNATHTTYGTNTTYAARGAYGGNYTNGCNMGN TTYGCNACNAAYAARTAYTGYGARCCNAGYCAYAAYAAYACNGAYAAYGTNTAYATGCAY YTNACNAAYTAYGCNATHAAYAARCAYAGYGARGAYTTYATHMGNGAYGAYGARGCNGGN AGYAARMGNMGNATHAGYACNATHAAYAARTAYYTNAAYGARAARGGNTAYGAYGTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ACNTGYAGYMGNCARAARCCNACNMGNGTNATHATHCARGGNYTNGAY TGYGCNGGNAARACNAGYYTNYTNTAYMGNYTNAARYTNGGNAARGTNGTNACNACNATH CCNACNATHGGNTTYAAYGTNGARACNATH---GARAGYGCNGGNYTNGARATHACNGCN TGGGAYYTNGGNGGNMGNGAYAARATHMGNCCNYTNTAYMGNCAYTAYTAYAAYCARACN GGNGGNTTYATHTAYATHYTNGAYAGYTCNGAYGTNGARMGNYTNGAYGAYGCNYTNGAY GARYTNAAYAGYATGATHYTNCARAGYGAYGARACNMGNGAYACNGTNGTNATGGTNYTN GCNAAYAARCARGAYYTNGAYAAYGCNYTNAGYCAYGCNGARATHGARCARAARTTYYTN GARAARAAYAARTCNGGNYTNAAYYTNTCNATGTTYGTNATGCCNTGYAGYGTNACNTCN GCNGAYGAYAARCCNYTNTGGTTYGCNTTYAAYCAYTTYGTNAARATGATHAARATGAAR AARGARGGN---------------------ACNATHATHGCNAAYCARGARGCNGARAAY AARACNACNGAYGARGAYGTNACNGTNTTYCAYMGNYTNATHYTNAARAAYCCNTTYCAY YTNYTNAARTCNGCNYTNTAYTAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGMGNTAYGCNTTYATGGGNCCN TGGGARACNGCNCAYYTNAAYGCNGARGGNATGATGGTNTAYGGNGAYMGNTAYGCNGAY ATGATHATHGGNATHCARGARACNTTYACNCCNCCNGTNMGNATGGARGGNGARACNYTN GARTCNATHCAYGARGAYATGATHAARACNACNGGNCCNYTNGARGAYATHCARAARMGN MGNCARTGGMGNGAYAARMGNYTNGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GGNGCNTCNGTN GCNTCNCARYTNGCNTGYNNNNNNTGYYTNNNNNNNTTYCARNNNGGNGAYNNNTGYMGN NNNYTNCCNTGYNNNCAYNNNTTYCAYNNNNNNTGYATHGAYNNNTGGYTNAARNNNNNN NNNNNNTGYCCNNNNTGYNNNNNNNNNGTN---TAYAARGCNCAYGCNMGNGCNAGYATH YTNAAYGAYTTYYTNGTNTTYAARACNCARTAYYTNATHAARACNYTNGARGARTAYAAY TTYCAYTAYTAYYTNGCNTCNCARAARGTNAAYAAYGTNYTNGTNCARACNCCNYTNGCN GAYMGNMGNYTNCAYTCNMGNTTYATGAARACNAARMGNAARAARYTNCCNYTNCCNACN GARAAYGAYGARTAYTTYTTYCAYGARTAYTGGTTYACNCAYAAYGARYTNAAYATHGAR GAYTAYAARAARCARAARATGYTNGARMGNCARACNAARGTNGARGARGCNMGNGARAAR GGNGARYTNTAYGARTGYTGYTGYTGYTAYGARGAYGARTGYYTNTTYGARGAYYTNGCN AAYTGYCCNGARGGNCAYYTNTTYTGYAARGTNTGYGTNGTNMGNTCNACNGARGCNGCN TTYGGNGARATGAARAAYMGNTTYCCNTGYYTNACNGGNGARTGYGAYGARAGYATHCCN YTNAGYACNYTNCARGGNATHATHCCNCCNAAYYTNTTYTCNAARATHGTNAGYMGNYTN CARGARGARGARGTNYTNCARGCNCARATHCCNGAYYTNGTNACNTGYCCNTTYTGYCCN TTYGCNACNATHATGCCNGAYCCNGAYGAYAARATHYTNAARTGYYTNAAYCCNGARTGY YTNAARGARTCNTGYMGNYTNTGYMGNGARGARAGYCAYATHCCNYTNAARTGYAAYGAR GTNGARAGYMGNGCNGGNACNAARATGMGNACNTAYATHGARAAYAARGTNGCNGARGCN GTNATGMGNAARTGYCAYAARTGYGGNAARMGNTTYYTNAARGAYACNGGNTGYAAYAAR ATGACNTGYGTNTGYGGNGGNACNAGYTGYTAYTTYTGYAARGARCCNAAYATHGAYTAY GGNCAYTTYGAYMGNAAYAARATGTGYGCNCARACNGAYCCNAAYAARATHCAYGARMGN GAYATGAARGARGCNGCNAARAARGCNATGGARGARTAYATHYTNGARCAYCCNGARGCN GCNGAYYTNGAYYTNTTYACNTGGTGYMGNAAYGTNTCNYTNACNMGNGTNYTNMGNCAR GARGARCCNACNGAYCARTCNGGNGARGCNGARAAYATGAAYCCNAARMGNCARGTNGTN GAYGTNGARACNAGYATHMGNTAYYTNGAYAGYAAYGCNTAYGTNGARGGNTAYGGNGAR AARCCNGTNTGGTTYCAYTAYMGNMGNAAYTTYAARAARAAYATHATGCCNCCNACNMGN AARACNTGYATHMGNAARGGNGARATHTCNACNGCNAGYCCNTGYCCNGTNTGYMGNGAY GARTAYYTNGTNYTNGAYTCNAARAAYACNAARYTNYTNGAYCARTTYATHTCNCCNTAY ACNGGNGARATHATHGAYTCNATGAARACNGGNYTNTGYCARGARCARCARAARAARYTN ACNGTNGARGTNATGAARGCNTGGGAYCARGGNTAYYTNGARATGAARGTNCCNTTYACN ACNTAYGAYTAYGAYGAYTAYAAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CCN TTYCCNGAYGTNGTNACNGCNGAYTGGTCNTTYYTNGARGAYAAYGCNTCNMGNACNAAR TGYYTNAARTGYAAYAARTCNMGNAARTAYTAYTGYTAYAGYTGYTGYATHGCNYTNCCN CAYATHCARGAYAARYTNCCNAARGTNAARYTNCCNYTNAARGTNGAYATHATHAARCAY CCNAARGARYTNGAYGGNAARAGYACNGCNCCNCAYGCNTCNATHYTNGCNCCNGARGAY GTNACNATHTAYACNTAYCCNTGYATHCCNGAYTAYAAYCARCAYAARGTNATHATHGTN TTYCCNGGNGARAAYTCNGTNAGYYTNGAYGARYTNAARGGNGTNGARACNGARACNTCN CARGTNGAYGAYAGYYTNACNAAYYTNCARTCNMGNAGYAARAARGAYAGYGARGGNACN AAYTGYTCN---------AAYAAYYTNTAYATHTCNMGNTCNGARGARGAYGCNYTNAAR AAYAAYAGYAAYGGNAAYAAYAARGCNAAYATHAGYGTNAAYATHCAYAAYAAYAAYACN GAYGAYAARCCNMGNATGTCNCARYTNGARTCNATHGARCAYYTNACNMGNAARMGNGTN YTNAGYAARGARGAYGGNGAYGGNATHCARGARGAYAAYGAYAGYGARTGYAARGAYTCN ACNATHACNGTNAARCAYCARAARACNCAYYTNMGNCARTGYCCNTTYGARAARGTNGTN TTYGTNGAYTGYACNTGGAAYCARACNAARCARATHGTNAAYGAYGARMGNYTNAARGGN YTNAARAARGTNGARYTNAARACNCARTTYACNCAYTTYTGGMGNAGYCARGARGGNATG CCNAARACNTAYYTNTCNACNATHGARGCNATHTAYTTYTTYTTYAARGAYTTYCAYTCN ATHTTYATHGAYCCNATHTAYMGNCAYGARTAYGAYAAYYTNYTNATGTTYTTYTGYTTY ATGTAYCAYAARATHAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TAY AGYACNAAYATHTTYTGGATHTTYTAYGCNYTNGTNCAYATGTTYGTNACNTTYTTYYTN TCNGCNCARGTNTAYTTYYTNGGNMGNTGGMGNGTNGGNTGGTCNTTYTTYAARMGNTAY ATHYTNTTYYTNATHAAYGAYTGYMGNMGNMGNTCNCCNCCNGTNAGYCCNAAYMGNTTY ATHATGYTNGTNATHGGNAAYATHATHAAYTGGACNTTYGCNYTNTAYGGNGCNATHACN MGNCCNGCNGAYTTYGCNAGYTAYYTNYTNGCNATHTTYATHGGNAAYYTNYTNYTNTAY TGYYTNTTYTAYGTNATHATGAARYTNYTNAGYGGNGARMGNATHAGYYTNYTNGTNATG TTYGTNATGTTYATHTGYYTNGTNYTNTGGGGNTGYTCNYTNTAYTTYTTYTTYCARCAY GTNACNTCNTGGCARGARACNCCNTCNGGNTCNMGNGARGGNAAYMGNGARTGYATHYTN YTNAAYTTYTAYGAYTCNCAYGAYGTNTGGCAYTTYYTNTCNGCNTTYAGYYTNTTYTTY TCNTTYATGATHYTNYTNYTNYTNGAYGAYGAYYTNTCNYTNAARCCNMGNAAYCARATH CCNGTNTTYGAYTCNMGNGCNGARGGNATHGGNGCNGTN---------------GAYACN CCNGTNGTNGTNGCNGAYGGNMGNAGYAGYGTNGARATHAARGARAAYGGNGARTAYMGN GGNGARGAYMGNATGGAYGTNTCNCCNCCNGARGGNACNGARGAYAGYMGNGGNCARGGN CARTGGAARTCNTCNGARGAYAAYTAYATHGCNTCNGCNGTNYTNGCNCARAARACNGAR CARGARGCNYTNCARGARGTNCARGARGARMGNGAYAARYTNYTNGARGARCARGCNAAY ATGAARAGYTCNYTNAGYACNATGGARGAYGARYTNTCNAARAARAGYGAYYTNYTNGTN GCNGARMGNGARATH--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AAYTTYGTN AARGAYTCNGARMGNGAYTGGTTYTCNGGNGARAARGGNTCNYTNGAYATGTTYATHGTN ATGAAYAARATGGCNYTNGCNAAYYTNMGNATG---GARAAYGAYGAYATHCARGTNATH GAYTCNGCNATGGGNGGNGTNAAYYTNGGNGTNGAYAGYGGNATHCCNATGGAYGTNGTN MGNGAYYTNCARGCNYTNYTNTCNGCNCAYCARYTNTCNACNTTYAARAGYAAYYTNAGY YTNGAYAARATHTAYCCNGAYTCNAAYGTNAAYTAYYTNAARTGGCAR---CCNAARAAY GARACNAAR---GAYTCNGARAARTTYACNGGNCAYATHCCNATHGARCARYTNGARATH AGYCAYAGYMGNAGYAGYGGNCCNGGNGGNCARAAYGTNAAYAARGTNAAYAGYAARGTN GARGTNMGNTTYCAYYTNGAYTCNGCNCCNTGGATHCCNGARTGGATHAARCCNMGNYTN ACNGARCARGARCARAAYMGNATHTCNAARGAYGGNTAYYTNATHATHMGNTCNGAYYTN ACNMGNAARCARATGYTNAAYCARGCNGAYTGYYTNAAYAARYTNMGNAAYATGATHTAY CARGCNTCNATHYTNCCNACNGARCCNACNGARGARGARATHAARAARAARGARCARMGN ATGATGAARGCNAARTCNGGNATHYTNMGNGARAARAARMGNAARTCNYTNATHAARCAR TCNMGNTCNAAYCCNGARYTN--------------------------------------- ------------------------------------------------------------ ---------------------------------------------------GAYYTNGCN TTYTCNCCNGTNAAYGAYCAYYTNATGGTNTCNGTNGGNYTNGAYAARMGNYTNGTNYTN TAYGAYGTNCARGGNAARAAYCCNATHAARACNATHGTNGCNGAYTAYCCNYTNACNTGY YTNGAYATGCARGAYGGNACNACNATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGGARGTNGAY------------GARCCNGCNTAYYTNACNATH YTNATGGGNGAYTCNAGYACNTCNCARTGGYTNTCNTGYATHATHGAYYTNAARAAYGCN GTNATHGGNAGYAAYMGNGARAARTCNMGNGCNGTNGARCARGGNYTNGTNCCNMGNYTN YTNGGNTGGATHGARGAYGGNYTNTGYCCNYTNGAYYTNAARACNGARGCNGCNATHGTN YTNGGNAGYYTNGCNAARGGNGGNCARGGNACNGTNCARAARYTNGTNGAYGCNAARACN GTNTCNGTNYTNYTNAARTCNYTNAAYACNTCNAAYCARAARTAYTGYGARGCNGTNYTN MGNTGYYTNMGNTCNATHTAYATGGARAAYACNGARTGYATHAAYATHYTNTAYGARGAR AAYAGYTTYGGNTCNTCNTAYATHCCNACNYTNYTNGCNATGACNCARCARTCNYTNATH TGYCARGARTGYGTNACNAAYATHTTYGTNTGYTGYTGYAARACNAARGARCAYCARATG TGYYTNYTNAAYAGYCARGCNYTNCCNATHYTNTCNCCNYTNYTNCARTCNAGY---CAR TAYAARATHCARATGCCNACNYTNMGNTTYTTYGCNAARGTNTGYTAYAARAAYACNGAR GTNTGYAAYGCNATHGCNAARGARGCNCARYTNGTNGARACNTTYGTNCAYYTNATGAGY MGNGAYAARCCNACNGARATGCARATGGCNGCNGCNGARATGYTNACNAAYYTNCAYMGN TGYGGNGTNATHCCNGCNAGYGAYTTYATHATHAGYMGNAARACNYTNGGNACNYTNGTN MGNATGTGYATGMGNGAYTGYACNGTNGARGARAAYGTNMGNGGNGCNGARGTNYTNGCN TAYYTNATHGARATHGAYCCNGAYYTNCARYTNACNGCNAGYTAYACNTTYCAYYTNATH GGNGCNYTNGCNACNTGYYTNCAYTAYCARGAYACNGAYAARGTNCCNTCNAGYGGNAAY AARGAYGTNGAYTGGGGNAGYGARATGMGNMGNGCNGCNTTYYTNGCNTTYGCNTCNATH AGYGCNAAYGAYGARGARATHMGNGARAARGTNATHAARCARGARGGNATGATHGARCAY ATHCARACNTCNYTNAGYAGYAARAAYGAYGGNGARGTNGCNGCNAGYYTNMGNTGYYTN CARTCNYTNACNMGNTCNGTNCARCARATHMGNACNGTNYTNCAYGAYAAYGCNGTNTGG AARCCNYTNYTNGARAARGTNMGNTCNGGNAAYAARGARATH---------------AAR GTNYTNGCNATGTCNTGYYTNTGYAAYYTNGTNYTNGARTTYTCNCCNAGYAARGARGCN YTNGTNGARAAYCAYGCNGTNGAYGTNYTNTGYGGNYTNTGYCARAGYGARGAYAAYATH GTNMGNYTNAAYGCNACNTGGGGNATHATGTCNTTYTCNTAYTAYGCNTCNGARGARYTN MGNACNAAYATHATHAAYAARYTNGGNACNGAYACNYTNGTNMGNMGNATHCARGAYCCN GTNYTNYTNATHMGNGARAARGCNYTNTGYATHGTNMGNAAYYTNYTNGCNGGNAARATG AGYATHGAYAAYACNGTNAARYTNYTNGGNAAYGARGTNATHGARGCNGTNTTYAARATH YTNTCNGARGAYAAYATGCCNTCNAAYGTNGTNACNCARGCNYTNTGYGCNYTNAGYAAY ATGGCNGAYGGNCCNTCNTGYAARGCNTAYATGATHGCNAARACNGAYGARATHAAYTCN GTNYTNCARTAYACNGARTAYCCNGAYAARAAYYTNYTNYTNCCNGCNATHCARTTYGTN AGYAAYYTNGTNGAYACNAGYGAYGAY------------------------GGNTCNTAY CARMGNATGYTNCARYTNAARACNYTNGGNGTNCARACNYTNYTNGARAGYYTNGTNGGN ATHGGNYTNGAYGARGTNGARCCNMGNGCNCARCARGCNYTNAARTAYTTYGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATHGAY AARGGNGAYATHCCNGAYYTNGCNAARGCNCCNGCNAGYYTNYTNGAYGCNYTNGARCAR CAYYTNGCNTCNYTNGARGGNAARAAR---ACNGCNACNACNCCNACNGGNTCNAGYAAR CCNTCNGGNTTYACNACNGCNYTNAAYAAYATGTCNAGYAAYACNTTYACNGTNAGYGAR GCNGARMGNAARMGNATHYTNGARGARGARAAYCARCARYTNCARAARCAYAARGGNYTN CARCAYGAR------AARYTNAARGARAAYACNTCNCCNCARAARGCNGGNCCNTCNACN ACNAAYAAYCCNTTYTCNAGYCCNTCNGCNGGNCARCARCARCARCARCARGAYYTNTTY GGNTCNCCNGTNAAYAGYACN---------GCNAARGCNAGYGAYGAYYTNYTNAGYYTN ACNTCNAAYCCNTTYGCNAGYAAYGTNCARGAYGTNATGGCNTCNGCNTAYCARGCNCCN GCNAAYAGYACNCCNAAYAAYCCNTTYGGNACNCCNGCNTTYCARACNAAYGGNATHGGN GCNGCN---AAYTCNAAYAAYTTYGAYGCNGAYTTYGCNAAYGCNTTYAAYAAYACNGGN ACNAAYTCNCAR------------GGNCCNACNCCNTCNTCNAGYGGNCCN---CCNGGN TTYGAYGCNTTYGGNGARGTNATGGCNCCNATGAAYAARTCNCCNTCNCAYCARGCNCAR AAYAGYCAYGGNGCNMGNTCNYTNGGNGGNGAYYTNGAYTCNTCNYTNGCNTCNYTNGCN TCNAAYYTNAAYGTNAGYGGNGGNACNGGNCARYTNAARAARGAYCAYCARTGGCARCCN AARGGNGARAAYAARYTNACNGGNGGNAAYCARTTYCARMGNCARCCNATHGCNGCNTCN ACNACNAAYCCNGCNCCN---CARTGGGGNCARCCNGGNTTYCARCARCCNAAYATGATG ---ACNGGNATGCCNAGYGGNCARATGATGTAYGGNCARCARATGGGNATGCCNATGGCN CARCCNATGATGCARCCNATGGGNATGATGGGNATGGGNCARCARCARCCNATGATGTAY GGN------GCNGTNCCNCARMGNATGCCNTCNCCNGCNGTNGGNTTYGGNCARCCNGCN GCNCCNCARCARACNCCNTCNTCNCARACNAAYATHAAYGAYCCNTTYGGNGCNYTNGAR AGYMGNAARMGNYTNMGNCCNTGGYTNTGGMGNCAYATHGAYGCNGAYTAYGGNYTNMGN TGGGTNAAYAARGARGAYGGNACNTTYMGNATGCCNTGGCCNCAYMGNAGYAGYMGNTGY TGGAAYAARGAYGAYTGYCARGTNTTYAARGARTGGGCNMGNTTYACNAAYAARTAYMGN GAYGGNGAYYTNGAYGAYTAYCCNGGNTGGAARACNMGNATGMGNACNGCNYTNACNAAR YTNAGYGAYTTYGARGARGTNCAYGAYYTNCAYAARAARGARGAYGARAAYCCNTAYAAR GTNTAYMGNTTYAARATGGCNGGNMGNCCNAARTCNGGNATHACNGCNGGNACNGAYGTN AAYYTNGAYTTYYTNACNAARGARGARAARGARGCNTTYYTNTCNAARAARATGGAYATG ATHMGNCARMGNAAYAARGTNATHAGYGARMGNCAYGARYTNATHGARGCNGAYMGNMGN AARGCNGARGARTCNGGNAAYGCNGTNAARGCNATHGAYAGYAARACNYTNCCNGCNGAR GGNGCNCCNAAY---AARCCNMGNGGNMGNGGNMGNGGNCARAGYCARGGNCARGGNTCN CAYMGNGAYGGNAAYMGNCCNAGYAARGAYMGNCCNAARTCNCAYGGNGAYACNTCNTCN TAYGARCCNATHGTNGAYGTNAGYGAYTTYACNAAYAAYMGNGGNGGNAAYAARGGNCAY CAYCAYCARTAYCAYCAYCAYCAYAAYCAYCAR------------------GARMGNGAY GCNCCNACNTCNACNCCNAARAAYMGNMGNAARCCNCAYCAYCARAARGAYGARGCNGGN ---CARAGYYTNATHGTNTCNTCNCCNGCNATGGAYTTYGAYTAYGARCCNATHGTNGAY YTNAAYGAYYTNGAYCAYMGNTTYGGNMGNGCNTCNTCNTCNTCNTCNTCNTCNAARCAR AAYAAYAARCARATGGAY------------------GGNAAYAAYAAYAAYAAYMGNGGN TAYAAYGCNGGNGGNCAYTCN---MGNTCNAAYMGNMGNTCNAARCCN---TAYGAYGGN MGNYTNAARGARAGYAAY---CCNCCNCCNGAYCCNTCNTTYAAYCCNYTNTCNGAYTGG MGNMGNGARMGNGGN---TCNGAYMGNAARGAR------------GGNTCNMGNTCNGAY CAYAARMGNCAYCCNMGNAAYTAYGGNGGNGGNGCNGAYYTNGCNAARGTNAARGAYAAY ATGAARACNATGMGNGARMGNGARAARGARMGNCCNGTNTCNTCNMGNAAYYTNGARATG GTNATGACNGGNMGNGARMGNMGNAAYCAYGARCARTGGAARCARGARMGNGARMGNTAY GAYAAYGARMGNATHCARMGNCARATGGGNGAYACNGGNGGNTGGAARMGNGARTGGGAY AAYGAYAARGTNGTNYTNGARTAYGAYGAY------CAYCCNCAYGCNAARATGGARCCN GCNAARMGNCCNGCNGGNMGNATHGGNAGYGGNMGNTTYGAYMGNGGNGAYMGNGARGAY MGNCCNAARGCNATHGTNMGNGAYGGNAARGGNGGN------------------------ ---------------------------------------------------------TCN TCNCARCAYGGNCCNTCNCARCARAGYCCNCCNTCNCAYCAYCAY---CAYGCNCCNYTN AGYCCNCARTCNGCNGARTCNAARGCNCCNGCNGGNMGNGGNMGNGGNMGNGGNMGNGGN MGNGGNMGNGGNACNGTNCARGCNCARAGYCCNGGNGCN---GARAARTCNCARMGNCCN MGNACNTGGTCNGGNGGNGAYGAYMGNTTYGTNGARTGYCARAARGARATGYTNGTNGTN AARTTYGAYAAYACNGCNGGNGAYAAYTCNGTNGARGTNGARTAYGAYGGNGARACNCCN YTNTCNCCNACNCCNTCNTCNMGNTCNTCNGGNTCNACNCCNGGNMGNGGNCCNACNGGN MGNACNCARAAYCARGGNGGNTCNAARCCNAARGGNGGNMGNCARCARCARTCNAAYCAY AAYCARCARCARAARCCNACNMGNAGYAARGCNGGNAGYGGNMGNATHATGACNGGNCAY CARCARTTYGTNGAYGCNGARTGGGAYAGYGCNMGNCAYTCNTAYGAYGGNTCNYTNCCN CCNACNTCNGGNAARGTNMGNACNYTNTCNTCNCAYTCNCAYAGYCARGGNGAYAGYGAR GARTGGGARGAYTGYACNGARTCNTCNGGNGCNCCNGARGARGARGAYTAY--------- ------CAYCARAARAAYYTNCAYYTNGAYTGYCARYTNAAYCCNGARGCNCCNGARTTY YTNCCNACNTCNCCNGAYTTYYTNAARACNCCNCCNGGNCAYGTNAARGTNYTNAAYTGG GCNGGNAGY---AAYACNCCNACNTCNCCN------CARTCNAAYYTNAGYCARCCNGGN TTYTCN------------TCNATHTCNTCNCCNMGNCAR------------CAYCARGAR ACNGGNTCNAAYCARTCNTCNTTYTCNTCNCCNGGNTCNTCNGCNTCNATHMGNGCNAAR TCNMGNMGNGARGARGTNGAYTCNATGCCNGARCCNGAYGARCCNYTNCCNCCNCCNTTY YTNYTN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TTYYTNACNGAYGTNGCNAAYGTNMGNACNATGGARCAYGGNYTN YTNACNYTNYTNAAYGAYTTYCAYTCNGGNAARYTNCARGCNTTYGGNAGYAAYGCNACN TTYAAYAARATGGAYGCNATHMGNATHCARCARGARCARYTNGCNAARCARCAYTTYGAR YTNGAYYTNYTNCCNMGNTCNGCNCCNAGYMGNATGAAYGCNGARGARTCNMGNAARGAR AGYAGYGARAARATGGAYAARYTNATHGARCAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GTNAARGTNATGGAYYTNATHGCNMGN GTNTCNMGNGGNGGNMGNCAYTCNAGYCARCARCARACNGGNGTNMGNAAYTTYAARMGN TTYAARAARACNGCNCAYTGYGGNAGYAAYGGNYTNCCNACNATHATHGGNGGNMGNGAY YTNGARCCNCAYAARAGYACNMGNYTNAAYCAYATGGAYGAYYTNYTNGARGCNGCNGTN ACNACNGARAAYGGNGTNMGNGARGAYGGNATGTTYAGYTGG------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHGAYGCNAAYGGNCCNMGNCCNGARCCNGTNTAYYTNMGNMGNGAR AARCARCARCCNCCNACNYTNACNGCNTCNAARCAYCCNCAYGGNACNAGYCCNACNAAY GGNAGYCAYCCNCAYACNGGNCARGCNMGNCCNYTNTAYTAYGGNAAYGAYAAYAGYAGY GTNAAYMGNCARTCNMGNACNCARACNACNMGNCCNGAYCCNATHCCNGGNCARCCNTAY GCNGGNGCNCCNGCNCARMGNGTNGGNAGYGCNCCNYTNMGNAARATG------ACNAAY CARGGNACNATHMGNACNAAY------GTNGCNAAYMGNTCNGTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------GTNGGNGAYGAYTCNATGYTNGARCARGGNMGNCARATGACNGCNGTNCAR GAYYTNGARMGNCARTTYCARGGNATGCAYATGCCNTCNGCNCCNGGNMGNCCNGAYATH GGNTCNCARTCNAARAARATHTGGGAYGAYGAYAGYAAYAARCCNGGNGAYCCNACNMGN GGNGGNATGTTYCAYCAYGGNTGGACNACNMGNGAYGAYACNTGGATGACNGGNGGNGCN AARTCNAGYAAYCARATHGGNGTNAAYATGGTNGARTAYGTNYTNGGNGGNGGNTCNCCN AAYAARATGGAYCCNGGNGCNYTNGGNMGNATHAARCCNTTY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGAGYACN TCNGTNAGYACNATGMGNGCNGGNGCNAAYAARYTNCCNGGNCCNAAYGAYAARTCNGCN AARGGNGAYATGAGYACNTCN---TCNCARCCNACNAAYGCNAARACNGAYGGNCAYTCN AARAARATGCARCCNACNCARGARCARYTNMGNYTNGCNCARATGATGAGYATHAAYCAR ATGGAYGCNGAYCCNAAYACNGTNAARCARYTNATGGAYATGACNGGNAARAGYGARGAY GTNGTNGTNATHGCNYTNCAYGAYGCNGGNAAYGAYGCNGAYMGNGCNGTNATGACNYTN YTNGARGGNGGNGARGARCARGAYGARTGGMGNGARTGYGGNAARAARAARAARAARAAY ACNCCNAARGARAGYTCNGGNAAY------------GARGAYCAYTCNGAYAGYMGNAAY MGNGAYMGNGGN---------------------------GAYAAYCARGAYATGCCNCCN MGNMGNGGNMGNMGNAAYGGNGTNCCNCCNCCNMGNYTNGCNMGNGGNMGNGGNMGNGAR MGNGGNAAYTTYGGNGAYMGNGAYMGNGARMGNAAYAAYGCNTCNGCNGARGAYTGGGAY AAYGAYAARGARGAY------------------MGNGGNCCNMGNGGNGAYMGNGGNGAY MGNGGNMGNTTYMGNGGNMGNGGNGGNTTYAGYGGNMGNMGNCCNGCNGGNGCNATGAGY AGYGGNMGNGGNGGNMGNTTYAAYAAY------GAYMGNGARAAYMGNGGNTTYACNMGN CCNMGNMGNTTYGARAARATGAAYAAYTCNCARCCNYTNGAYGGNCCNGARCCNGARATH GAYACNTGGACNAAYGARACNGCNGARACNAAR---ACNACNAARGAYACNGAYTGGAAY AGYTGGAAYGAYTCNTGGGTNAAYGARGARGAYCARTGGACNGGNACNYTNGARGARACN AARGTNTTYACNCCNTCNCAYGTNAARATGCCNGARCCNGAYCCNGTNACNAAYGARCCN CCNAGYACNYTNGGNCARMGNYTNGAYGTNGGNAGYYTNTTYGARAGYGCNAARTTYACN AARGCNCCNGAYTAYAGYAARCCNAGYGGNGAYTCNTAYATHAAYCARTTYAAYCARGCN GCNACNGARTCNATHAARAAYACNATHGGNATHGGNAAYGCNTCNMGNCCNCARATHCCN ATGTCN---------------CCNCCNGAYACNTCNGGNTCNYTNGGNYTNGCNAAYYTN GGNCARAARACNGCNCARGTNCARGGNAGYTCNGTNATGCCNTCNYTN------CARCAR TCNGCNCARCARAAYACNYTNCCNCAYGCNATGGCNCARYTNTCNCARATHTCNCARCCN GCNTCNCARTCNACNAGYATGTCNCARATGGGNATGGGNTCNCCN--------------- ------------------------CCNAGYCARGCNGGNGCNAAYCARGCN--------- ---------CCNCARCARTCNMGNATHCCNGCNGTNGTN------------------CAR CARCARCARAAYYTNCCNCARTCNAAYATG---AAYAAYATGCCNCARMGNCCNAARACN CARMGNTCNAARYTNCCNCCNCCNTCNAARATHCCNTCNACNGCNGTNGARATGCCNGGN CAYATHCCNMGNAAYCCNCARYTNGAYGTNCARTTYGGNYTNGAYTTYGGNTCNGARTCN TCNGTNCARTTYGGNTTYGGNGGNAGYGGNGAYAAYACNACNGTNACNAGYTCNTAYTCN ACNACNTCNAAYGGNTCNGCNGCNGTNATHTCNAAYCAYYTNAAYCARGGNCAYATGACN CARTCNGCNGGNGAYGGNAAYTCNGTNTCNCCNATHATGCCNTCNCCNTCNGCNGGNTCN ACNAAYGTNCCNTCNGGNATHGARACNCARGGNCCNCCNAAYMGNCARGGNGTNTTYCAY AAYTCNATGTAYTCNTCNCARCARCARAARACNGARAGYCARTCNYTNGARYTNGAYCAR AAYAARGTNAAYGAYTCNATHCCNTTYYTNTCNACNCARYTNGARMGNAARTCNAGYCCN ATGGCNTCN---CARMGNCARGGNCARACNAAYCARAAYYTNACNTCNGGNCCNATGACN TCNAGYAARAGYGAYTCNACNAGYGCNGTNGCNAAYAAYAGYTAYTCNGTNGCNAAYGGN TAY---TCNTCNTCNTAYCARAGYCAYCCNAARGGNTCNTCNATHTCN------CAYACN GCNACNTCNCARCCNTCNCARACNTCNTCNTTYCAYGGNCARTAYCCNGTNAAYCARTCN TCNTTYCCNTCNAGYGGNCARAGYCCNTTYCCNACNCCNCCNAAYGCNAAYGCNTTY--- CCNTCNGCNCARCCNTCNCARTTYAGYACNTCNAGYTCN------TCNCARAAYCARTTY TCNACNGGNCARAAYCARTAYTCNGTNGGNACNTCNACNYTNACNCAY------CARAAY AAYCARTTYCCNTCNAGYGGNCARAAYAAYTAYGGNAGY---GGNTCNTCNCARTAYTCN GGNTAYCARAAYAAYAGYTCNTTYCCNACNCAYCCNCARTCNCARACNAAYTTYCCNTCN AGYCARAAYGGNGGNACNGGNGCNGTNYTNTAYCCNACNTCNACNCARTCNGGNGTNTCN TCNTAYACNACNCARTCNGGNTCNTAYCARTCNCCNTCNGCNGGNTCNTAYCAYTCNTCN MGNGAYTCNACNACNAAYATGGCNGTNAGYACNCARTCNAGYAGYGGNATGACNTTYCCN AGYCARCCNCARGCNTCNAAYYTNAARCCNGCNACNACNCARAGYAAYACNAGYTTYAAY TCNCARAGYTAY---CCNAAYCCNCCNCARYTNCARCCNTCNTCNYTNGCNAAYAARYTN GGNGARAGYYTNTCNAARATHTCNATGAARGAYTCNTCNTCNGTNYTNGAYAAYCAYCAR TCNTCNCARTAYGARCAYACNCCNTCNCCNGCNAGYGTNCCNACNAGYGTNAGYYTNCCN TCNGCNTCNAGYTCNGCNTCNYTNTCNACNGGNACNAAYGCNATHTCNTCNACNTCNACN GTNACNTCNGCNTCNCCNGCNTCNMGNGTNGCNTCNATGCCNTCNACNTCNGGNAARGCN CCNCCNAAYYTNCCNCCNGGNGTNCCNYTNATGGGNCARTAYATHATGGGNCARAGYACN ATHCCNCCNTTYTAYAGYGTNCARCCNCCNYTNTAYGGNTAYGARGAYGTNCARYTNYTN CARCARMGNATGCCNATGCARACNGGNAGYTTYTAYGAYGTNAAYGCNTTYCCNGCNGCN CCNGCNGGNTCNACNYTNCCNACNGGNMGNGAYCCNCARCCNCCNATHCCNAAYGTNCCN TTYTCNGGNACNTCNGAYACNAARYTNGCNMGNGTNGAYGCNCARAGYCCNAAYGCNTCN AGYCARCCNCARAGYGCNCAYTCNGCNGCNCARCARCCNYTNTTYAAYTTYCAYTAYGGN TAYTAYTAYCCNTCNATGTTYCCNGGNGCNGCNGGNYTNCARTAYCCN------GTNAGY CARATHCCNCCNGTNACNAAYGCNGCNGCNCAYCARGGNACNACNGCNACNACNCARTTY CARAARTCNTAYCCNTCNCAYGTNTAYACNACNAARGGNTAYGAYGARGTNAAYCARGTN CARGAYTAYTCNAARACNGGNTAYGGNAGYTCNCARACNTCNGGNAARGCNTCNGGNACN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNCCNTTYTCNCARYTNTGGGCNGTNYTNTTYTTYGCNATGYTNATHACNYTN GGNYTNGGNACNCARATHGCNACNGTNACNACNGTNCAYACNACNYTNATHGAYCARTTY CCN------------MGNGTNTTYTCNAAYGGNAARMGNACNTTYTGYTCNYTNGCNTTY YTNYTNGGNYTNTCNTTYTGYACNCARGGNGGNATGTAYGTNGTNGTNYTNTTYGAYAAY TAYGCNGCNACNTAYTCNYTNYTNGTNATHGGNATGGTNGARATGATHGCNYTNGGNTGG GTNTAYGGNGCNGARMGNTTYYTNGGNGAYATHGARYTNATGYTNGGNAARMGNCCNCCN CAYATGTGGGCNATHAGYTGGAARTTYGTNGCNCCNATHGCNATHATGGCNATHYTNATH TTYAGYYTNGTNGAYTTYGARCCNTCNAARTAYGARGAYTAYATHTTYCCNGGNTGGGCN GAYGGNATHGGNTGYATHYTNGCNYTNATGTCNATHATGGCNATGCCNATHGGNGCNGCN ATHAARYTNGCNTCNGTNAAYCARACNYTNATHGARGTNYTNMGNGARYTNAGYAARCCN ACNTCNAGYTGGGGNCCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------YTNTTYMGNATGGGN ACNYTNGTNYTNGTNYTNYTNGGNAARTTYACNGCNGAYATGGTNYTNTTYTCNGAYYTN GCNGARYTNGTNTAYGTNATHGTNGAYYTNTCNGCNTTYTTYYTNATHTTYATHGCNGCN TGYATHYTNTCNGCNGGNACNAAYGARACNTGYGAYCAYATHGAYTGYAAYAGYAARTAY TTYGARGAYTCNTAYTCNGCNTCNAARGCNGCNCARGCNGGNGCNTGGATHAGYACNTTY YTNTGGYTNTTYATHGGNATHTGYGGNTTYYTNACNYTNTGGMGNGCNGGNAARATHCCN TTYYTNTCNGGNGGNGGNGCNGCNAARTCNGAYCCNAGYACNACNGGNCCNGAYTCNAAY CARCCNCCNATGGARACNCCNCCNTAYAAYCCNGAYGAYCCNCCNAARTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CCNCARGCNGTNAARGAYGARGARCAYATH GCNAAYGCNGTNAAYCARATHYTNGCNCARGCNGTNCARCARCARMGNGARYTNACNYTN GCNGCNCARAAYGCNCCNCCNCCNCCNCCNAARAGYMGNAAYAAR---ATGGAYTCNAAR TTYAARAARMGNATHCARMGNMGNYTNTAYCAYGCNTGYACNAGYGAYTGYGAYAGYGAY AGYGAYATHGAYGGNYTNGGNACNTCNTCNYTNCCNYTNACNGARACNTGYATGGARTAY TTYCARGAYAGYTTYCCNGGNTCNGARGGNYTNGGNMGNYTNGAYATGCCNATGGCNGCN ACNGTNACNAARMGNAAYCARGTNTCNCCNTGYTCNGTNGTNYTNTCNATGATGTAYGCN AARMGNYTNMGNCARGGNAAYGARAARTAYYTNCARTCNATGTCNTCNTCNGAYGTNTTY TTYATHTCNATGATGATGGCNAGYAARTAYYTNTAYGAYGARGGNGTNGAYGARGARGTN TAYAAYGAYGARTGGGCNGCNAGYGTNGGNCAYGAYACNGARGAYGTNAAYMGNATGGAR ATGGAYTTYYTNAARGARATGGAYTGGCAYYTNTTYACNMGNCAYGARGAYTTYGAYAAY ACNYTNACNGCNGTNGARMGNMGNYTNGCNYTNMGNGARGGNGTNMGNMGNGGNTGGTTY ACNTAYACNGARATGTCNGTNYTNYTNGAYTGGGAYCCNATHTAYAAYATGTGGAAYCAR GTNGGNGTNGAYTGYACNAARATGGTNTCNYTNYTNTCNGCNATGTAYGTNGCNAGYYTN GTNAGYGTNATGGGNTCNGCNGCNATHGCNATHCARYTNTCNGGNCCNATGGCNTCNGTN ACNGTNGCNGCNGTN--------------------------------------------- ---AARTGYTGYCCNYTNAARTGGGAYTAYAARTGYAARCARGARAAYGTNGGNTTYCCN TGYTTYTAYAAYGCNAAYTCNAAYAARTGGGARTGGTGYTGYCCNTTYTGGCCNMGNYTN YTNATH------GCNMGNTGYGARTGYTGYCARTGYGCNATHYTNACNACNGCNTGYGCN CAYGARGGNMGNTGYCARMGNMGNTTYAARAARCARGGNTTYTTYGCNGTNTGY---TAY MGNAAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGTNTGYGTN CCNTGYTTYYTNATHCCNGTNATHYTNTGGATHTTYCAYAARTTYATHCARCCNTGGYTN TCNAARATHTGGAGYAAYTCNGARAAYTAYGTNACNAGYAAYYTNACNTGYCCNATGCCN CARAARAARAAR---------AARATHCCNGARGCNACNGAYACNGGNAAYAGYGAYATH ACNGARGARGAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CAYCCNGAYGGNAARGARATGCARATHAAYYTNACNGGNTTYYTNAAY GGNAARAAYGCNMGNGTNTTYGTNGCNGARYTNTGGACNCAYYTNTGYAGYGCNCARGAR AAYATHACNGGNATHCCNAAYGARTTYYTNGARCARAARAARAAYGARATHAARCARMGN CARGARGARCARGARMGNYTNCARGARCARYTNAARAARAARGARGARCARATHAARGAR CARYTNTCNMGNGARMGNMGNGARYTNGARAAR--------------------------- ---AARGAYYTNAAYAAYYTNTCNCCNGAYMGNCCNAARCCNATHGARACNAAYGGNYTN AARCCNTCNGCNGAYAGYGGNGAYGGNACNGAYGTNAARGAR---GARATHAARTCNGAR CCNAARCARGARACNTCNGAYAAYCARGARGGNGARGARAARACNGARGARAARGARGAR AARAARGARAARTCNCCNGARMGN---------MGNMGNGARAAYMGNGAYAARGAY--- ------------MGNGARMGNMGNMGNCAYTCNMGNTCNCCNGAYMGNCAYMGN---CCN MGNTCNMGNACNCCNGAYMGN---MGNGAYMGNGAYMGNGAYMGNMGNCCNGAYCAYGGN CAYMGNMGNTAYTCNCCN------------------------------------------ ---CCNMGNMGNMGNTCNMGNTCNCCNMGNMGNMGNTCNCCNCCNCCNAARMGNMGNTCN CCNCCNMGNMGNTCNCCNTCNCCN------------MGNAARMGNTCNCCNAARAARTCN GARCCNGCNAARMGNGAR---------MGNTCNAGYAGYGGNAGYAGYTCNAGYGGNTCN GARGAYGAR------------TCNGGNAARGARGGNTCNTCNCCNGARAARAGYGGNATH CARCARMGNMGNAAYTAYMGNAARCAYGAYGARGARAGYGGNAARGARTCNTCNTCN--- ------GAYTCNTCNGAYGAYGGNGCNGCNAARCCNMGNMGNMGNCCNTCNCCNCCNMGN GAYMGN------------MGNAAYGCNMGNAGYCCNTCNCCNMGNMGNMGNMGNTCNCCN CCNTAYMGNMGNCCNAGYCCNMGNMGNCARAGYCCNCCNMGNMGNMGNTTYCCNTCNCCN CCNMGNMGNMGNATGAGYCCNGTNCAYCAYMGNMGNAGYCCNTCNCCNMGNMGNMGNTCN CCNCCNMGNATHTCNCCNMGNMGNMGN---------AGYCCNCCNMGNMGNMGNCARATG TCNATHTCNCCNMGNMGNMGNMGNTCNTCNTCNCCNCCNMGNMGNCCNCCNTCNCCNTTY CARGCNMGN---MGNMGNMGNCCNTCNMGNTCNCCNTCNGAYTCNCCNGTNMGNMGNMGN MGNGCNTCNCCNCCNCCNTCNCCNCCNGTNAARTCNAARAARAARAARGTNTCNCCNCCN CCNTCNGARTCNGARGAY------AGYTCNAGYTCNGGNGAYTCNTCNCCNTCNCCNCCN CCNGCNTCNAARMGNCCNACNAARGGNAARGAR---------GCNCCNCCNCCNAARMGN CCNGCNCCN---------------GCNAARAARCARAARCCNCCNAGYGAYGARAGYTCN TCNTCNTCNTCNGGNTCNGARGAY---AGYGAYGAYGAYTCNGGNTCNCCNACNTCNCCN CCNGCNAARCARTGGMGNGARGCNACNCCNCCNMGNGTNGTNAARTCNCCNAARCARCCN TCNCAYGGNTCNMGNTCNMGNTCNMGNTCNCCNGTNAAYMGNMGNGAYMGNMGNCCNAGY CCNCARCCNMGNAARMGNGCNGCNGGNTCNMGNTCNCCNGTNCAYGGNMGNGAYMGNCAY GGNTCNCCNCCNMGNMGNAGYTCNMGNTCNCCNCCNCAYMGNMGNTCNCCNCCNMGNGAY GARTCNTCNGGNAGYMGNMGNCARMGNMGNGAYACNGAYCCNTCN---GAYCAYGARYTN GGNMGNMGNGAYMGNMGNCCNMGNGAYGCNGCNAGYCCNCCNMGNAARMGN--------- CARGTNMGNTCNCCNTCNCCNMGNCAYGARMGNGAYGGNGGNMGNMGNGAYCARMGNAAY MGNMGNTCNCCNCARCARATGGARMGNCAYAARGARGCNCCNAAYAARCARGAYAAR--- ------------MGNAARGARAARMGNCCNCCNTCNTCNGAYAGYAGYAGYGGNAGYAGY TCNGAYGARGARGARGARGARGARGARGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TTYACNACNGARATH GARYTNMGNACNGCNYTNGAR---------------------------MGNGGNGCNGCN TAYCCNCARTTYGCNAGYCARAARATHMGNAARATHACNTTYGGNTCNTGGGAYCCNATG CAYAGYCARAARCCNGAYGAYYTNGTNTCNYTNGGNTTYTTYTAYGCNGGNTAYTCNGAY TGYGCNMGNTGYTTYTAYTGYGGNYTNGGNYTNAARTAYTGGMGNCCNAAYGAYAAYGCN GCNTAYCARCAYGCNMGNTTYMGNCCNCARTGYAARTAYAAYCARTTYGTNAARGGNCAR GARTTYATHGAYCARGTNCARMGNAAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------GAYGAYYTNAAYGTNYTNYTNGTNGGNGCNGGNGAYATHMGNCAYATHYTNACN ACNATHTCNMGNMGNTGYMGNCAYAARAARMGNAARYTNAAYTTYTTYGTNGTNGARTCN GCNYTNGARYTNTAYGCNMGNGAYATGYTNYTNATGATGGTNGTNYTNGARCARCARCAR AAYATGGGNYTNCARGARAARACNGARGTNTTYYTNGARATHCAYGGNAAYACNYTNYTN MGNCARCARACNAGYGAYTAYATHCARAARATGTCNCAYCARYTNATHMGNATGGTNACN GAYTTYGAYTAYATGGARAARAARTTYCCNATHTTYGAYYTNGAYCARYTNAARTAYAAR GARMGNGAYTTYYTNGARGGNGTNYTNAARTTYTGGMGNAAYCARGARAARGTNAARTCN CCNTTYGAYATHAGYAARTGYTGGGAYYTNMGNYTNMGNCARYTNYTNGGNGTNMGNTAY GAYAGYMGNATHAAYGCNTTYGAYTGGGAYTAYAAYATGGARATGGTNGARMGNGGNGGN TCNATHATHCAYYTNCARCARTAYAARTCNTGGMGNAAYGAYGGNATHGCNTAYACNATH MGNGARGGNACNTAYGAYGTNCCNAAYMGNACNYTNTCNTCNGCNATGGTNTTYAARCAY GARGGNGARMGNTAYCCNMGNMGNGGNTAYTGGGGNGAYATGYTNGTNTCNCCNTAYGTN GCNTTYGGNGTNGARACNGARGARAARTCNTTYTAYAARAARCARAAYAAYCAYCAYATH AARACNGCNGARGAYGTNGCNGARTAYAAYGTNACNTCNYTNYTNCAYGARYTNATGATG GGNGARAARTAYGTNYTNCCNAARGTNGARGARAARGARAGYGAYGTNGARAAR------ ------CARACNGCNACNYTNGARGARATHGTNGARGARCCNGAYCAYCCNGAYAARGAY AARGARAGYCARGARATHTCNGARTCNAAYGGNGAYAAYGCNAAYAARGARAAYGAYAAY GTNCCNGAYGCNAARYTNTAYGARTGGTGYCCNYTNGARGAYGTNAARATHACNTTYYTN CCNYTNTCNAGYGTNAARGARYTNAGYAARAARAGYAARTAYCARAARYTNTTYAAYGCN GTNTAYTTYTCNAAYAGYATGGTNCAYYTNYTNACNCCNGAYGTNACNTCNATHTTYGCN GAYMGNTGYGCNGTNGTNYTNGARACNGCNYTNTTYATGYTNAGYYTNAARAARCCNGAR GTNCARGARTTYATGAARMGNGTNAGYGGNYTNGCNGAYACNGCNGGNTGYAARCCNYTN GAYGCNATHGAYGAYYTNCARGAYTCNTAYGCNGCNTTYTAYTAYGARMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNATHTCNTGYTTYGTNYTNYTNACN------------ACNGCNGCNGAYMGN MGNCCNMGNGGNGTNTCNYTNGARAARGCNTCNTTYTAYCARGGNGCNACNGARTTYCAR TGYYTNACNAGYGGNAARGTNYTNCCNATHGAYCAYGTNAAYGAYGAYTAYTGYGAYTGY GARGAYGGNTCNGAYGARCCNGGNACNCCNGCNTGYGCNAAYGGNATHTTYTAYTGYGAR AAYAARCCNTAYAARGGNCAYTAYATHAARACNTCNMGNGTNAAYGAYGGNATHTGYGAY TGYTGYGAYGGNTCNGAYGARTTYGAYGGNACNATHTCNTGYCCNAAYACNTGYGTNGAR AARTAYGARCARGARAARGTNCARCARGARGCNYTNMGNYTNCARCARTCNGARGGNTAY AARGTNAARCARGARTAYATGCARCARGGNAARMGNGCNAARGAYGARAARMGNTCNAAR YTNAGYGARYTNGARAARGARAARGARATHYTNGTNAARGARAARGARGCNGCNGARACN GTNAARAAYGARGCNGARGARCCNGARAARGTNGCNATHGARGARCAYAARAARGCNTGG GARYTNGTNAARGARGARMGNCARAARGCNAARGAYGCNGTNAARGCNGCNCAYGCNTTY TCNACNYTNGAYGTNAAYAAYGAYGGNAAYGTNGAYTTYCCNGARYTNATGAARCAYCAR GARTTYGAYATHGAYTCNGAYGGNACNGTNAGYGARGARGARGCNAARGARTAYYTNGAR GAYAAYGARCARGTNGAYYTNACNYTNTTYACNGARAARATHTGGCCNAAYATHAARGAR ATHTAYAAR------------------------------YTNGARCARGARGARAARCCN GARGARNNNNNNNNNGANGANNNN---------NNNGGNNNNGARNNN---GANNNNNNN NNNNNNNNNNNNNNN------------TCNTCNTTYGAYATHTCNAAYGARAARYTNGAY ACNGAYACNCCNGARGANGARAARGANCCNNNNNNNNNNGARNNNNNNAANNNNNNNNNN NNNNNNNNNGAYNNNNNNNNNNNNNNNNNNNNNGAYNNNNNNNNNAANNNNAARGAYNNN GARACNGARATHAAYGAYATHAARAARTAYYTNGARATHGAYTTYGGNCCNAAYGARGAR TTYGCNGCNYTNAARGGNCARTGYTTYGARTAYACNGAYMGNGARTAYACNTAYMGNYTN TGYCCNTTYGAYAARAGYACNCARAARAAYAARAAYGGNGGNATHGARACNTCNYTNGGN GTNTGGGGNAARTGGCAYGGNCCNGAYGAYGAYAARTAYGAYNNNNNNNNNNNNGANAAY GGNNNNGGNNNNNNNAAYGGNCCNAGYMGNTCNACNCAYGTNAAYYTNCAYTGYGGNTCN ACNAAYGCNYTNACNAGYGCNTCNGARCCNAGYMGNTGYGARTAYCARTTYGARTTYACN ACNCCNGCNMGNTGYGARGARCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARCARGCNCCNGARATHMGNACN ATHYTNTCNGARTCNGAYMGNTCNTTYMGNGAYAARATHGAYTCNMGNGGNCAYACNCAR GCNTTYATGGAYMGNCARATGAARTGGGARAAYGCNCAYTGGCARCCNGARCCNMGNGAY GTNACNGTNAAYTTYGAYGAYTTYAAYGTNATHATHMGNYTNGAYTTYCARGCNGARTTY TCNAAYGTNYTNACNGTNTTYYTNTCNGTNGTNGAYCCNGGNGAYTCNAARATHTGYAAR GTNAARATHAAYGGNATHCCNGCNGAYATHGCNGCNMGNGCNAARGCNTAYAGYATHCAR GARGGNACNGARACNTCNYTNTGYAARAAYTAYYTNCCNYTNCARGAYYTNCARMGNYTN AARGCNGAYATGYTNATHGARATHTGYGTNACNTGYTTYYTNCAYGAYGGNGARCARGTN GARAARTCNGTNGTNGARAAYYTNGGNYTNCCNYTNGTNTCNMGNYTNCAYYTNTGGAAR CARTAYCCNGAYYTNACNMGNTGYCARGARGCNGARGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATGGAYYTNTCNCAYAAYAARATHTCNGAYYTNAAR TTYYTNTGYGAYYTNCCNTCNYTNAARAGYYTNGTNYTNGAYCAYAAYMGNATHACNTCN CAYGTNCARATGACNTCNTGYCCNAGYYTNGARACNYTNTGGGTNAAYCAYAAYMGNATH GARAAYYTNGGNYTNTTYATHTCNAGYYTNACNAARMGNTGYCCNAAYYTNMGNATHYTN TCNATGATGAAYAAYGTNGCNGCNCCNAGYTAYTTYAAYGGNGGNACN------TTYCAR CARTTYAARGAYTAYMGNTAYTTYGTNATHAGYCAYATGACNAARYTNGARGTNYTNGAY GAYACNAARGTNACN--------------------------------------------- ------------------------------------------------------------ ------------------------------GGNGAYGTNGGNTTYGAYGARMGNGARATG YTNCCNGAYGCNGGNCAYYTNGAYGAYGGNYTNTAYAARACNGAYGARMGNGAYYTNGAR GARGCNGCNGAYCAYMGNGGNGAYGGNYTNGAR---------GAYAARGAYAARCCNATG GAYATHGAYYTNCCNCCNCCNGTNGTNGGNGAYGGNTTYGGNGAYGGNTTYATGGAYGAY GAYGAYGGNTGYGARGAYGAYAAYGAYAAYTTYGGNGAYGTNGAYCARGAYTTYTTYGGN CARGAYTTYATGGGNACNGGNGGNYTNTTYGARGAYCCNCCNGTNATGCCNAGYGARTCN TCNGCNCCNGARTCNGTNCARCCNCCNTCNTCNCCNAARGARGAYGCNGCNTCNAGYAAR CCNAAYGAYGARGCNGARGAYACNGTNAAYYTNCARGCNAGYAAYGCNGGNGTNTCNGCN GTNTCNAGYGTNGGNGGNGARCARACNACNYTNGTNCAYAAYGARGARGARGCNTTYGCN YTNGARCCNYTNGAYATHACNACNGTNCCNGGNACNGARMGNAARGGNAARMGNAARMGN AARYTNATHGTNGAYGARCARAARGGNATHCCNAGYGARACNATGAARYTNCARYTNTCN GAYACNTCNGAYATHGTNACNTCNYTNGAYYTNGCNCCNCCNACNAARAARYTNATGYTN TGGAARGARACNGGNGGNGTNGARAARATHTTYGTNYTNCCNGGNMGNCCNATHATHTCN AARATHAGYAARCAYYTNTTYTCNATHAAYYTNGTNTGYAARTCNGTNGCNGAYGAYTAY GARCCNGGNGCNAGYMGNATHGAYYTNGAYATGGCNCCNGARGTNGCNMGNGARAAYGAR MGNAAYAGYACNYTNCARGAYACNMGNYTNTCNGARATGTCNACNATHATHGARGARCCN TCNGAYGTNTCNAARMGNTCNTCNMGNCARCCNTCNYTNGTNGAYACNTCNMGNMGNTCN GAYATGTCNATHYTNGARAAYCARTCNYTNTTYGAYCARATHCCNGAYACNATHCARCCN GTNGAYATHCCNACNGAYCCNAAYAGYATHGTNCCNACNATHAAYTCNATGYTNGAYGAY GGNCCNCCNTCNGTNGCNCCNTTYTCNGTNCCNCCNCCNCCNTGYGTNACNTTYGAYATG GARCCNGARCARGAYAAYGARYTNATGCCNGARAAYGARGARCARGARGARAARMGNTGG AGYAARMGNACNCARGTNATGCARGAYATHTTYGARMGNGGNTTYAAYGAYCARGAYAGY YTNAGYTTYAARGAYATGGCNMGNAAYYTNCAYMGNAARCARGCNGCNTCNMGNTTYTAY ACNYTNYTNGTNYTNAARAARCAYCARGCNATHTGYACNGARCARCCNGARCCNTTYGGN GAYATHTAYATHTCNMGNGGNCCNCARTTYGGNATHGCNTGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TTYYTNGAYACNCCN TCNGAYATHGGNAARCARGTNGCNGAYYTNMGNGCNCAYGTNMGNGAYTTYATHYTNGGN CAYGARGARGARATHGARACNYTNGARAARYTNGTN------TCNAARATHTCNTCNATG GAYGTNGARYTNGCNAAYTTYCARGTNGARMGNGARYTNTTYGARYTNTCNCAYMGNTTY TCNYTNTAYGARAAYGGNAAYTTYGAYATHCCNTAYGCNCARAAYGAYGTNAARMGNAAR GCNTCNATHCAYCARCCNGGNAAYYTNTCNTCNAAYGCNGTNAAYAAYGGNMGNMGNAAR GGNCARCCNCARACNACNGARTAYATHAARGCNTGYAARGARGCNGARGTNACNGARTCN GTNCARGTNGARATHTCNGCNYTNCARCARGARGTNGARAAYYTNGARCARGARYTNAAR CARATHCARATHAAYAAYYTNAARMGNYTNCARAGYATHACNGARCARGAYTAYAGYTCN ATHTGYATHYTNCCNMGNCAYTTYAARCARTTYYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATHACNCCNAAYYTNGGNACNTAYMGNGGNGGNTCNYTNCCNAAY GTNAAYCARATGGCNACNAAYCARAGYATHGAYYTNCARGCNACNYTNCARCAYYTNGAY GAYATGAARCARGGNMGNACNAGYATHGAYMGNCCNCAYCCNMGNCARGAYMGNCAYMGN CARACNGTNGGNCCNCAYMGNMGNAAYTTYCCNCCNGAYAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGTGGTCNCCNGAYGAYGCNGGNGTNGTNTTY TGYGCNTGGGAYCAYGARCCNTAYMGNYTNGGNYTNAARCAYTGYTGYCARMGNAARGGN GGNYTNTAYTTYTAYGAYYTNGARAARGGNTCNATHGAYYTNYTNAGYTCNGARGGNMGN GCNGTNMGNTTYCCNMGNTTYAGYCCNGAYATGAGYMGNYTNGTNTAYATGGAYACNCCN GTNGGNGGNGGNCAYCAYCARTGYTCNMGNYTNYTNATGATGGAYTGGGCNTCNAARAAY GTNAARGTNGTNGTNGAYATHGTNAARCAYGCNTCNGCNACNTCNTTYCARGGNATHTTY ACNGCNGCNGTNCCNMGNAAYATHTGGTTYGARGAYAAYATHCAYYTNTCNTTYTCNACN GCNTGGMGNAGYAAYACNACNGCNATHATHGTNAAYACNAAYACNGGNCAYATHAARAGY YTNTCNCAYGGNAAR---------AAYATGTCNGTNYTNAGYGTNAAYAARAARAAYGTN YTNATGTCNTGYTCNTCNATGACNACNCCNAAYTAYYTNGTNYTNGCNCARYTNGARGAY ATHGGNAAYCCNGARACNGCNAARYTNATHCAYCCNGAYGGNACNCCNGAYAAYYTNGAY TGGYTN---TCNTGGGARYTNYTNACNCAYAARCCNACNGCNGAYMGNGTNAGYCCNGTN AAYGCNAAYYTNGAYTAYGARAGYATHYTNTGYYTNCCNCCNAARGCNAARGAYGGNAGY YTNCCNCCNYTNATHGTNTTYGTNCAYGGNGGNCCNCAYGTNGGNTTYGAYACNTCNTTY AAYTTYTCNACNAAYYTNTTYTGYYTNTGYGGNTAYGCNGTNGTNATGGTNAAYTAYMGN GGNTCNTGGGGNTTYGGNCARGAYGGNATHGARTCNYTNYTNGGNGCNGTNGGNGAYGTN GAYGTNMGNGAYGTNCARGGNGCNYTNCARGAYGTNATHTCNAARGGNGTNGTNGAYAGY ACNMGNYTNTTYATGTTYGGNGGNTCNCAYGGNGGNTTYYTNTCNACNCAYYTNATHGGN CARTAYCCNAARACNTTYAARGCNGCNGCNGTNMGNAAYCCNGTNATHAAYYTNGCNTCN ATGTTYTCNACNACNGAYATHATHGAYTGGATHTTYGTNGARGGNGGNTTYCCNTAYGAY YTNACNTCNGTNGCNGAYGAYAARATHYTNCCNGAYYTNTGGAARMGNTCNCCNYTNTCN CAYATHGAY------------------------AARGTNATH------------AGYCCN GTN------------------YTNYTNYTNGTNGGNYTNGARGAYAARMGNATGATHAAY TCNATHGTNTGGTTY---------------GARCARGARGARGCNTTYGTNACNYTNGCN ACNAAYGAYACNTAYACNYTNGGNTGYYTNGTNYTNGGNAAYTCNYTNMGNMGNGTNGGN ACNACNMGNAARYTNGTNGTNATGATHACNGAYGGNGTNACNCAYTCNATGMGNGARCAR YTNAGYGCNYTNTTYGAYGARGTNGTNGTNGTNAAYGTNYTNGAYAGYGCNGAYACNTGY AAYYTNAAYYTNYTNGGNMGNCCNGAYYTNAGYGTNACNTTYACNAARYTNCAYTGYTGG MGNCARACNCARTAYAARAARTGYGTNTTYATGGAYGCNGAYACNYTNGTNYTNCARAAY GTNGAYAAYYTNTTYGAYMGNGARGARYTNTCNGCNGCNCCNGAYGCNGGNTGGCCNGAY TGYTTYAAYTCNGGNGTNTTYGTNTTYTGYCCNTCNGARCARACNTAYGTNAGYYTNYTN CARYTNGCNGTNTCNTCNGGNTCNTTYGAYGGNGGNGAYCARGGNYTNYTNAAYYTNTAY TTYAGYTCNTGGGCNACNGCNGAYATHGGNAARCAYYTNCCNTTYACNTAYAAYGTNGTN TCNCARGCNTTYTAYAGYTAYYTNCCNGCNTTYAARCARTTYAARGAYCARATHAARATH GTNCAYTTYATHGGNGCNGTNAARCCNTGGCAYCAYCCNTAYAAYATGGAYAARMGNACN GTNACNCCNYTNCCNGARACNGGNCAYAAYCARCARTTYYTNCARATHTGGTGGGAYATH TTYATGGAYTCNGTNCAYCCNTGYYTNGAYCCNCAYYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNATHGGNAGYYTNATHACNGGNTTYYTNTAYGGNMGNTTYGGNCCN MGNTGGACNTGGCARTGYYTNTCNATHATHTCNATHGTNATHYTNYTNGTNTAYTTYYTN YTNAAYATGTTY------------------------------------------------ ------------------------------------------------------------ ---------------------------------------CAYTAYATHTAYCARGGNGAY ATHTAYGCNGTNCCNGAYAARGGNACNAGYYTN------MGNGAYGARAGYGARAAYCCN ATHATHTCNMGNATGAARGARATGGTNGTNGARAAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GAYGGNGAY GCNACNCCNCCNTTYTCNGGNGGNAGYACNCCNCARAGYCARTCNMGNGCNCCNTCNCCN GCNTGGAGYGARAGYAGYGGNAAYATGAGYGCNAGYAGYATHTCNGGNTCNTCNTGYCCN MGNCARATGTCN---ATHGGNAAYAAYCCNGTNCCNMGNCAYAARMGNCCNTCNCAYMGN MGNGCNGARGTNAARMGNMGNGAYAARATHAARACNAGYYTNGAYGARATHAARAGYTGY GTNCCNTCNYTNCARGAYAARGGNAARYTNAGYGARTCNGCNATHYTNTTYAARGCN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MGNYTNTCNGCNYTNCCNGARYTNAAYCARTCN YTNTCNGAYYTNCAYTTYMGNCARAGYYTNATGCARMGNATHCARGARTGGTCNAGYTTY GCNGARGARTAYAAYAARTCNYTNAAYCCNACNCCNGARTGYTCNCCNATHMGNTTYGTN MGNMGNAGYMGNTCNYTNGAYMGNCAYYTNAGYGAYTCNTCNATHATHGCNACNGARTCN GARATHCCNTCNTCNAARCCNYTNGARATHGARCCNGTNACNGARAARAAYYTNGARTCN YTNGARTAYGARYTNCAYGAYATHCARGGNGARTTYGARTCNATHACNTCNAARYTNCAY GAYYTNATHGARCAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN GCNGARAGYGTNGAYGGNMGNGTNATHTTYGTNGGNYTNCCNAAYGGNYTNGCNGCNATG GAYGCNYTNTCNCARTTYCCNYTNCAYAARTGGGARGARGAYCAYGCNGARATHACNAGY ATHAARACNTAYYTNATHGCNCCNGAYTAYCAYYTNATHACNACNGTNGAYGAYATGGGN ATHGCNMGNATHTTYYTNTTYGCNTTYGAYCAYATHTTYTTYATHAARGCNYTNAAYGAR AAYAGYCCNGARGGNACNTCNAARATHYTNTGYCARAARTGYGARGCNTCNAAYGARGGN GAYTAYGTNGGNGTNTCNTTYGARAAYACNGGNAAYAARGARATHTGGTTYGARGCNCAR AARYTNCCNGTNGARAAYTGGATHAARGARYTNGARACNATHCARGCNGCNATHAGYAAR CARAARGAYGARCAYGARAARTCNATGACNGAYATGACNGGNCARGGNGGNGAR---GCN GARCAYGARTCNCARCCNAARATGTCNGARGAYACNAARAAYGAYGARGTNTCNGTNAGY GTNGARTCNGTNATHGARAARYTNGGNACNAARTTYAGYCAYCCNTCNGTNGTNTTYAAR GCNAARCCNCCNGCNCARMGNCCNCCNGCNCCNAAYCCNTCNTCNAGYATHGCNTCNGCN GTNTCNAARGTNGAYCARGGNGAYGTNYTNGGNACNGGNACNAAYCAYGTNYTNGGNGCN TCNCAYYTNGARTCNMGNGAYGCNATGTTYCARCAYAARCARGARAGYYTNYTNGARTTY YTNCCNACNGARGARGARGARAARCARATHGTNGTNACNTTYCAYTTYACNAAYACNAGY MGNATGATHCCNCAYGGNATGGARCAYTCNACNGCNTCNAAYAARCCNGTNTCNGTNGCN YTNTGGTGGTCNGGNACNCARCAYATHTGYCAYTAYTCNYTNYTNAAR---ACNGGNAAR GAYATHGARTTYAARCCNGAYATHGTNTGGCCNTGYTCNGAYACNATHACNTGYTCNACN ATHAGYCCNTGYGGNTCNCAYATGGCNTTYGGNYTNTCNAAYGGNAAYYTNGCNYTNTGG GAYTAYCARATGGGNYTNCCNAARGCNGTNYTNACNGTNTGYGGNAAYGGNGGNGTNAAR GARYTNMGNTTYYTNGAYCCNACNYTNTTYCCNTCNGAYCCNCCNGARTAYCCNCCNTAY CCNGTNYTNTCNGCNACNTTYATHYTNGCNGARTAYTGYGAYGGNACNCARGCNYTNTTY GAYACNTGYGAYGGNAGYCARCARATHCCNMGNGTNATHGCNACNGTNCCNGARAAYGAY GAYGAYATHCARACNYTNATHAARGTNATHCCNTCNYTNCCNGARYTNATGYTNTTYGTN AARAARAAYGGNTCNATGTAYATHAARGAYGTNGGNACNGGNGCNTCNYTNTGYCARGTN CAYYTNCCNTCNACNCAYACNATHCARACNCCNTGGAGYCCNATHTTYGCNYTNGGNGCN GGNGGNCAYATGYTNTAYYTNAARGGNGARGGNCARGAYGTNAGYGARGAYGGNGARGTN AGYGAYATHTCNTGYYTNTTYAARTTYAAYYTNMGNGARTAYCCNATHYTNGARGARTAY TGGGCNMGNCCNMGNGARAARACNAAYYTNATHGTNTAYACNACNTGYCARCARMGNYTN GAYTTYYTNATGAARGARMGNYTNCARCARCARGCNATGMGNAARCCNMGNATGCARAAR CAYTGGGGNCARYTNMGNGGNGARYTNGAYATHATHCARAAYGCNMGNGARATHGCNGTN GAYACNYTNMGNYTNTCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNACNGCNTAYGCNACNCCNCCNACNYTNYTN CAYMGNGTNGGNYTNGARTCNAGYTCNACNGGNTCNTCNTTYCCNGCNGAYTTYACNAAR CCNGTNCCNYTNGCNGTNATHTCNCCNGGNMGNMGN---------------------AGY GTNTGGGGNAARCCNACNAAYCCNATHCAR---CCNTGYTCNYTNACNGAYGTNATGAAY GARCARYTNGCNTCNGARYTNGARGCNMGNGARAAYGAYGARAARGCNGCNGCNACNGCN GGNAAYTCNGARGCNYTNACNAARCCNCCNTCNGCNGCNGCNGCNGCNACNACNGARAAY YTNACNGAYGARGARYTNGCNGCNAARYTNGCNGCNGARGAYAGYGGNTAYGAYCCNAAY GAYGARATHATHGCNYTNATGYTNCARAARCARTTYGAYAARGARTAYGAYACNGCNYTN TCNAARMGNGARCARCAYTAYAAYGGNAAYTGYAARGTNGCNGTNTCNTTYGARAAYTAY AARMGNAARCAYATGCARTCNGARTAYCARAAYGARGAYTTYGAYGAYGAYGAYGAYAAY TAYGARGAYGARYTNCCNCARTAYCCNCARCARACNGARTGGGARAAYAGYCAYYTNACN ATHGGNAGYMGNGGNTAYGTNMGNCARGGNGAYAGYATHGTNACNAARCAYGAYAARGTN ATHTGYGGNMGNMGNAAYGCNCARMGNYTNATGCARTTYCCNCCNGARTTYGAYTGYGGN GAYGGNGARGGNATGGAYATGCARYTNCCNAAYMGNGTNTAYAAYAARYTNAARCARCAY TCNYTNTCNGARACNAARAARAGYCAYAARGTNTAYGARAARAARGAYCAYTCNACNGCN ATHAARGCNGTNGAYGARAARACNMGNATHYTNATHTTYAARATGATHAAYGCNGARTTY YTNATGTCNGTNGAYGGNGTNGTNAGYGARGGNAARGARGCNGTNGTNYTNAARGCNATH GGNGGNMGNAARGAYAAYATGGARYTNCCNGARCAYGTNATHYTNAARGTNTTYAARACN TCNATGAAYGARTTYAARACNMGNYTNAARTAYATHCARGGNGAYTAYMGNYTNTCNAAR GAYATHYTNAARAARTTYAAYCCNMGNAARYTNATGMGNGTNTGGGCNGARAARGARTTY YTNAAYYTNMGNAARYTNCAYMGNAAYGGNGTNATGTGYCCNACNCCNYTNGCNYTNAAR AARCAYATHYTNGCNATGGCNTGYATHGGNGGNGAYMGNCCNGCNCCNAARYTNAARGAY GTNGTNTTYAAYACNGARGAYTTYCARGAYGCNTTYGARCARACNGTNGARYTNATGAAR YTNATGTTYGGNAARTGYAAYATGGTNCAYTGYGAYTTYAGYCCNTAYAAYYTNYTNTGG CAYCARAARAARGTNTGGGTNATHGAYGTNGGNCARGCNGTNGAYMGNGAYAAYCCNAGY TCNAAYTCNTTYYTNTTYMGNGAYTGYMGNAAYATHTGYGAYTAYTTYAARCARGGNGGN GTNTAYGGNGTNCCNTCNGCNGARAAYYTNTTYAAYGARATHACNAAYTAYGCNTTYGAR GGNGARGGNGARGTNTTYGARTCNCARTCNCAYMGNTAYGAYGARGARGGNTAYGCNTTY AAYTTYTTYTTYGARYTNTCNGARTCNGCNMGNTCNCARAARTAYGTNACNGGNGAYAGY AGYGGNAGYGAYAGYGARGGNGAYGAYGTNGAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CARGCNAAYYTNAAYAAYATHCAR YTNGGNAAYCCNTGGCAYGTNAGYATHGAYMGNCCNGGNYTNGARACNTCNATHTAYATH CCNCCNGGNGGNTCNGTNGAYTCNGGNGCNATGTTYAAYATHATHATHMGNCAYACNMGN ACNCARCARYTNTCNACNTAYATGACNMGNTAYTAYACNCAYCCNYTNGTNTTYTGYYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGAAY CCNAGYMGNTCNYTNGGNAGYGCNGTNGCNTCNGARGAYTGGGAYGAYCAYTGGATHTAY TGGATHGCNCCNATHGTNGGNGGNGTNYTNGCNGCNGTNACNTAYAARTTYGTNYTNAAY CCNTAYMGNGGNGTNGTNAAYATGGAYGARGCNGTNCARAARATGAAYGGNGARACNAAY TTY--------------------------------------------------------- ---------------------------AARATGGCNGAYGARYTNCCNYTNTTYCCNAAR GCNACNTCNATGTAYYTNCAYAGYGGNAAYATGATHAAYTGGAAYMGNYTNAARMGNMGN CCNAAYYTNTCNTCNTCNGAYGARYTNTGYGARGTNATHACNGAYACNYTNAAYGCNTAY GTNGARGCNGCNGAYAARACNGARYTNCARTAYGTNACNGARGTNTAYAARGTNAARTCN GARAAYGTNGARGTNATHGARGARAGYGARMGNGGNGAYGTNAARATHACNGTNAARGTN TTYATHTGYGAYTCNCARTCNCCNAGYGTNATHGGNGAYGCNATHACNAARGTNYTNAAY GARYTNGGNACNACNTTYGTNGARACNYTNYTNYTNGCNGTNTGYCCNAGYGTNGGNGAR GAYCARGAYCCNGARGARGTNGTNACNYTNTCNACNGTNGARGGNTAYTGGAARGCNATG GARGARYTNGTNGCNAAYGAYAARGTNYTNTCNYTNGGNATHTGYGAYTTYGGNAARGAR GGNYTNGARACNYTNTAYAAYTGGGCNCARGTNAARCCNTGYGTNAAYCARGTNAAYYTN GARTCNTGYTGYGTNYTNCCNAARGAYYTNACNGARTAYGCNAARTCNATHAAYGTNCAR YTNYTNACNCAYAAYGAYMGNCCNGCNTTYATHACNAARGARYTNYTNCARGARAARATG GCNAGYGTNACNACNGARMGNGAYAGYGAYGCNTGGACNCCNGARTGGGTNGTNMGNTAY TCNGGNATHYTNAARTGYMGNGGNATHATHAARACNAARGGNTAYATHTTYCAYGCNATG MGNGAYAAYAARAARMGNATHYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATHCCNTCN AAYYTNTCNGARGCNCARCARMGNCARTAYGTNGTNCARYTNCARATHGARGARATHACN MGNAARYTNMGNACNGGNGARYTNGGNATHCCNTCNAAYCCNGARCARMGNTCNCCNTCN CCNGARCCNATHTAYAAYAAYGARGGNAARMGNYTNAAYACNMGNGARTAYMGNACNMGN AARAARYTNGARGARGARMGNCAYAARYTNATHCARGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------TCNCCNATHTGYTCNACNYTNACNACNCARAGYATHATGTCNTCNTCN TTYTCNGTNATHTCNCCNATHTCNTCNTGYACNGCNGCNYTNACNTCNAARGTNGTNYTN MGNAARGAYAARAAYMGNMGNGTNYTNGAYMGNCCNAAYAGYATHGCNTTYTCNTCNTAY CCNGCNTGYGAYYTNATHTCNAARACNGCNGAYGGNAAYGGNGCNAARYTNAGYCAYCAY GAYGAYTCNAGYAGYGCN---ATHTCNYTNGGNCAYGCNMGNMGNGCNTCNTCNYTNAGY CCNGAYATHCCNTAYCAYMGNGGNMGNACNTCNTGGGCNTGYTAYTCNGARMGNGARGTN TAYMGNCARATHACNGCNGCNATGGARAGYGCNATGYTNMGNACNCARGCNTAYCCNMGN CARTCNCCNTCNAAYTGYTCNGGNMGNGTNTCNCARCAYTCNGGNGCNTCNMGNAARGCN MGNAGYYTNGAYAAYATHATHGAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TTY CCNYTNACNATGGARCAYYTNYTNGARCARCARTGGGARGCNGGNGCNCAYTTYYTNATG GARCARAGYGARCAYTTYGAYATHTCNTCNYTNYTNAAYTGYYTNCAYCAYTAYAARACN GAYATHMGNCARYTNGARGAYGARGTNMGNGAYYTNACNTCNCARMGNGAYCAYYTNATG GCNATHAAYGCNMGNYTNTCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ACNCCNGAYATHGTN MGNGARGARGTNGAYGTNYTNAARMGNGAYTTYAAYAGYMGNYTNAARCARATHYTNTTY AAYTCNYTNACNACNTCNTTYTAYGCNACNGGNGTNCCNGTNTGGTTYTCNCARATGAAY ACNYTNTAYTAYGAYTCNTGGTGGATGTGGCARCAYGTNTCNYTNACNTGGYTNAGYGCN YTNYTNATGYTNACNGCNCAYTTYYTNCCNCCNCAYTAYYTNCAYYTNYTNCAYAARAGY GCNMGNCAYYTNGGNMGNTGGCARMGNATGGARGCNMGNCAYGCNCAYATHCCNTAYAAY GCNTGGTCNGARYTNCARGTNTGGCCNCARGGNGCNYTNGTNAARCAYGTNMGNGGNYTN TTYAARGCNGARGGNATHAAYGTNACNGCNGARCCNGGNAAYAGYYTNCAYAGYMGNTTY TTYYTNYTNTTYCAYCARCCNATGMGNGTNATGAAYTGGYTNGTNTTYYTNACNTGYYTN ATHATGGCNTAYCARGCNTTYAARYTNGTNCARAGYTCNGARTGGAGYCAYATHATHTCN YTNGCNYTNYTNATGTTYTGYAAYTTYTAYACNYTNTTYAARYTNATGMGNGAYTGGTTY ATHATGGGNAARGTNTAYAARGAYCAYGAYTAYGTNGTNTCNAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------MGNTGGGCNGCNATHATHYTN GGNAGYYTNACNCARTAYATGCCNACNCARGARCARATHAARAGYGCNTTYATHATHAAR GAYCAYATHGARATHGCNATHAARCAYMGNCCNGAYGAYTCNYTNYTNTAYCAYATGATG GGNMGNTGGTGYTAYTCNGTNTAYATGYTNTCNTGGGTNGARMGNAARGTNGCNTCNGCN YTNTTYGCNACNCCNCCNACNGCNACNYTNGARGAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CCNAARAARCCNGAYMGN GTNCCNCARCCNAAYCCNATHGAYGAYGGNGGNGARGAYATHTAYGAYGARGGNGAR--- TCNGARAAYYTNTTYGCNTTYCARTGGTTYCAYGGNGAYATHGAYMGNAARGARGGNGAY MGNMGNATHTCNTCNYTNGGNGARATHGGNGCNTTYYTNATHMGNACNAGYTCNGGNAGY TCNGGNAARAARTAYCCNTAYACNYTNGTNATH--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYACNATHTCNCCNTCNGGNYTNCARYTNCCNGAYTTY YTNTCNGAYGGNCCNYTNGTNGGNGGNAARCCNACNATGCCNYTNAGYATHAGYMGNCAY GAYGAYMGNAAYGCNGAYGARGAYGARGAYATGYTNACNCARATHMGNGCNYTNCARGAR GARAAYMGNAARYTNCARGAYAAYYTNACNMGNATGAARCARAARTAYGARGAYAARAGY AARMGNATHATHCARYTNAARMGNGAYYTNGARCARCARAARAARAARGARGCNGARGAR ACNGCNGTNATGGARAARGCNGTNYTNCARGTNGARGARAAYYTNGTNACNACNACNAAR MGNGCNGTNCARGCNGARTCNGCNGTNTCNAARYTNAARCARGARGTNAARGGNYTNCAR AAYCARGTNMGNYTNYTNACNGCNGARAAYGARGCNTAYAARAGYGGNGAYGGNGGNYTN TCNGAYATHMGNGARMGNACNAARTAYACNTCNGARCARYTNCARYTNGGNGCNGARACN GCNGARAARAGYYTNAARGAYYTNATGCARGGNGTNGARAARATGAARYTNYTNTCNCAR GTNYTNGCNAGYTGGGARAARATHACNGARGTNAARCCNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYGTNTAYTGYATHMGNGCN YTNGTNMGNAGYTGYMGNAAYGARGAYAARYTNGCNYTNATHGAYYTNGAYTAYGCNYTN TCNTTYAAYCCNAAYCAYGTNAGYTGYYTNGTNGTNMGNGGNGCNATHACNMGNCCNTGG TCNCCNAARTTYCCNGGNGAYATHCCNMGNYTNAAYAARTAYYTNMGNAARGCNGARAAR YTNAAYCCNGAYTCNCARTCNTAYTTYAAYGTNGAYAGYTTYAAYCAYCCNTGYGTNCAR GAYTTYTAYGAYMGNATGYTNTTYACNYTNYTNGTNCCNCAYACNATGACNGARATHAAY YTNACNCCNGAYAARCCNAGYAARAARCARATGGAYTCNAGYCCNGARYTNMGNMGNAGY GGNTCNAGYCAYTCNGTNAAYTCNCAYAAYGGNTCNCCNACNMGNATGGGNTCNCCNACN GARAARYTNGAYCCNTTYMGNTGYGGNACNYTNTCNGTNAAYGARAAYMGNYTNTCNACN MGNMGNMGNYTNGAYTAYGGNGARGCNGTNMGNAARCAYAAYTCNMGNCCNAARACNGCN TCNGARTAYATGGCNGTNYTNGARAARGARMGNCAYAARMGNATGGARGCNTCNGCNMGN GCNCARTCNGCNACNTCNTCNTCNTCNATHGARMGNTGYCAYTCNTCNCARAARTCNGTN GAYMGNTCNTCNACNACNAAYTCNAGYGGNMGNACNACNAARACNMGNAGYACNAARGCN TTYGTNTTYGARACNCCNAAYAAYTAYTCNATHCCNGTNTTYCARCCNATGAAYATHGCN GAYGCNCCNMGNATGTAYTAYMGNCCNTGGMGNGGNGAYAARYTNCCNATHGGNGARGTN ACNCAYCCNCARCCNTCNCCNGCNTTYTAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNATGGCNCCNACNCCNTAYYTNATH GGNGTNCCNGCNAGYTTYTTYGGNTAYAARAARGAYTTYCAYATGCCNGAYGAYGTNAAR ACNCAYYTNAARCARGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNATHATGGGNCARCAYCCNTCNMGN CARGAYATHYTNCAYAARGARGTNTGYGAYYTNAAYATGMGNAAYTGGYTNTGYGCNAAY GTNGCNATGMGNGAYACNTCNAARGCNYTNGCNGTNTGYYTNCAYMGNMGNATHTCNCAR ATHCAYAARGARATGTCNMGNGCNGTNGGNGGNGGNMGNCARTGYACNAARAAYTGYACN MGNAAYMGNATHGAYTTYTGYTCNGTNTGYGARMGNTGGTCNMGNGARATHATHGCNATH TGYGARCCNGAYTAYMGNGCNMGNATHAAYTGGTCNMGNYTNAAYTCNGCNGARTGGCCN CAYAAYCCNTAYGARGTNGCNMGNGCNYTNATHCCNAARGCNCAYMGNYTNTAYTAYAAR TGYTCNGARTTYCAYGARGAYTTYMGNTTYAGYYTNAGYTTYATHGARAAYTGYACNGAR ATHCCNGTNTCNMGNTCNYTNTGYGARAARTCNTGGCARTTYMGNAGYMGNYTNAARMGN AARAAYAGYACNATGMGNATGGGNTGGGGNGAYYTNGARGAYGGNATHTCNGCNATGATH TCNYTNGTNTCN------------------------------------------------ ---------------------------------------------CARGARYTNMGNGCN MGNGAYATHACNYTNGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG GARCARCARYTNGCNAGYYTNGGNAARGAYTCNATGGGNCCNMGNAGYYTNGGNAGYACN ACNTCNGAYAGYTCNGAYACNTTYCCNGCNTCNTCNGCNAGYNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNACNNNNNNNNNNNNNCCNTCNNNNACNNNNNNNGCNGAYATHAGY AAYCARGTNACNMGNYTNAARTCNGAYYTNCARGTNYTNMGNMGNCARACNCARYTNAAY GTNGARGCNATGMGNGARGARTTYATGAARGCNGCNAAYTCNATHAARGTNGTNATHTCN TCNGTNCCNGGNGCNGAYAAYCARGTNAAYTTYCAYAARMGNGTNGARGCNACNAARMGN AARACNGCNTAYGTNAGYGAYAARGTNCAYGTNGAYAAYGARYTNGGNGAYYTNGARAGY AGYGTNGARGARYTNMGNTAYGAYATHYTNAAYCAYCARTGYMGNGTNCARYTNACNGAY GTNGARGGNATGGCNYTNYTNYTNAGYAAYATHACNAARAAYYTNGCNGAYYTNAARGCN CARTTYCCNGARGTNCARGARAARATGGCNGARGTNATGMGNAAYGARATGACNATHGTN AARGCNGARGARAAYTTYYTNGTNGARGARCCNTCNAARATHGARAARTCNYTNATGMGN TGYAARAARYTNACNGGNACNYTNTAYACNYTNAARMGNYTNGCNTCNGTNCARGAYCAY CAYMGNCCNCAYATHCCNAAYATHGCNACNTCNACNGCNGCNACNATGACNGARGARGAY CCNAARAARACNYTNYTNGARAAYATHMGNGCNYTNGTNCCNGAYCAYGAYMGNMGNGTN CARAARYTNGARGCNMGNGARGCNGCNMGNCARMGNATGAARAARATHAGYACNCARAAR GARGCNYTNAARTTYGGNAARAGYYTNGARATGGCNTCNAARGGNYTNMGNCCNTGYAGY ACNCAYGAYGAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYAARTGGTAYMGNATHAARGCNGGNYTNTTYYTNACN TCNGTNACNGGNTGYTCNGTNATHGCNGGNTTYGGNYTNACNYTNGGNATGGCNAARAAR CAYGAYCCNMGNCAYTTYGCNAARGGNYTNGTNGGNTCNAARGARYTNCCNGARAGYGGN GTNGCNYTNGCNACNMGNGCNYTNGCNMGNGCNTCNYTNTAYTCNGTNACNGGNTTYGGN YTNGTNTGYTTYGCNGTNTGGAARATGATGGGNGTNCAYAGYATGGTNGARTTYMGNGAR AARGTNGGNAAYGCNYTNCCNMGNYTNAARMGNAARGARAGYACNGGNMGNAAYGARTTY GCNACNATHMGNGAYYTNTTYCARTAYATHATHGAYGARGAYAARAARGCNAARACNYTN AARACNGARAARGARGARGARGARTGYGAYTAYTAYMGNCARMGNTTYAAYAGYYTNAAR ATHGTNACNGARGAYTTYCARAAYCARYTNACNTTYTAYAARGAYMGNTAYMGNGGNATG AGYACNATHCARYTNATHYTNAARGARTCNMGNCARGARAAYGTNMGNYTNTCNAARCAY GTNAARGCNYTNGARACNTCNATHTCNATHYTNCARAARMGNYTNGAYAARAAYGGNYTN TCNAAYAGYGTNAAYATHCARGAYGCNGARYTNTTYGTNCCNGGNGCNTCNAARCARACN TTYGAYAAYYTNGCNAARGARACNGTNMGNYTNMGNTCNYTNYTNAARCARGARAAYGGN CCNTTYGGNAARAARTCNGCNAAYGARTTYGARGAYATGAARATHGCNYTNAARGARGCN GAYCARGARAAYAAYGARYTNAARAAYAARATHAARGAYATGGARGARGTNAARYTNAAR YTNGTNAGYGAYTTYGARAGYTCNATHCARAAYYTNAAYAARGARMGNCARGARGARAAR GARAARTTYGARAARGARYTNAARGCNMGNGAR------------CCNCARAARYTNATG GARAARATGCARACNGAYTCNGGNGCNGTNCARGARYTNAARGAYYTNYTNACNAARACN GTNGARAARTGYGAYYTNYTNAGYGAYCARCCNTCNCCNMGNAAYGAY---CARACNMGN ATHCCNTCNGTNTCNCARGARGARTAYAAYMGNYTNGARCAYGARCAYAARAARGCNGTN GAYATGAAYCARAARTGGCARAAYTAYAGYAAYGAYMGNGARAAYAARATHCAYGTNYTN ACNGARMGNATHAARCARYTNTCNGAYCCNCAYCAYATGACNGCNATGGTNGARGARGCN TCNAAY---------CARAARACNATHCAYYTNAAYAARGAYYTNGCNAARAARGAYGCN GARATHYTNGARYTNMGNAARCARATHACNGCNYTNTCNAARGAYYTNGCNGAYACNMGN AARCAYCARYTNCARATGCARCARGAYAAYGGNACNGTNGARATHYTNAARCARCARATH CARGTNTGYACNGARGAYTTYAAYACNGARMGNAARGAYMGNGARCARGCNGTNCARAAR GCNMGNGCNYTNCARGAYGAYGTNACNMGNYTNAGYACNGARAAYCARGCNYTNAARMGN CARATHGARCARYTNAARAARACNACNGARCARCAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATHAARYTNGCNTTYATHCAYAAYYTNAAYAARYTNAARMGNTTYYTNAARCAR GCNGARYTNGAYCAYTAYGCNYTNTAYAGYGCNYTNTCNTAYYTNAARAARTGYGGNTGY GGNACNYTNATHYTNMGNTAYGTNAARYTNGAYGCNGGNTCNGARACNAARTCNGTNYTN ACNGCNYTNGARAGYTTYATHAGYTCNACNGGNCARACNYTN------------TGYCAY GCNTGYTAYGGNTGYCARTAYGARACNTGYGGNGAYCAYTAY------------AAYACN AAY------GARYTNGGNGARTGYGAYGAYGAYCARTTYTGYGTNAARTAYAARACNGTN GTNTGGATHAARGAYTCNGGNGAYATHYTNGGNAAYMGNACNGARTCNTCNGTNGTNACN MGNTCNTGYGARTCNAARAARGGNAARAARGARGGNTGYATHGGNTGGCARAAYAAYGGN GGNATHACNYTNAARTGYTGGTGYGGNACNGAYGGNTGYAAYAGYGGNMGNTCNYTNAAR CCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GCNAARGAYGAYTTYCARGARMGNTGYGARACNGARAAR MGNGARTTYTCNAAYMGNYTNAARTCNGTNAAYCARAARTAYAGYATGYTNCARAGYCAR AAYACNGARATHGARGCNGAYTTYATGAARYTNAARCARGAYATGGARAAYYTNMGNGCN GARCAYATGCARACNGARTCNCARCAYGCNCARGARTAYCARACNYTNAARCARGCNAAR GARAARGARATHTCNGAYYTNAGYGTNGARYTNGCNACNGTNAARAARCARAAYGARGAY YTNCARATGACNGTNTCNACNYTNCARTCNCARATHCARAAYCAYGARTCNGCNAARCAR AAYYTNYTNGAYCARAAYGCNAARYTNCARATGGCNCARTTYCARCARCARAARCARYTN GARYTNCARAAR------------CARAAYGARGARAAYGCNATGAARGCNAARCARYTN CARCARCARCAR------------------------------------------------ ------------------------------------------------------------ ---------------------------CCNGTNTCNTCNYTNAGYAGYYTNTCNACNAGY AGYATGACNCCNACNACNATHGAYATHAARCCNAAYACNAARYTNYTNGGNCARATGGTN CAYAARAAYTAYTCNGGNTCNAGYAARTCNAARGGNCCNGGNGGNAGY------------ ---------------------------CARGARACNTAYGCNTGGAARYTNAARAARYTN AARAARACNATHAARGAYTAYATHTTYATGAAYGGNGCNATHTGYGAYGARGTNYTNMGN ACNGARGARAARYTNGCNMGNGTNAARGARGARMGNMGNTTYYTNYTNMGNAARYTNYTN CARTTYCARTCNYTNAAYGARYTNGCNGGNATHACNAAYAARGCNGAYACNCCNGCNGCN ATGGTNMGNAAYYTNAARGCNGCNGTNGCNCARGARAAYGCNYTNGCNAAYGARACNAAY ACNAARGGNTCNAARGGNACNAARMGNAAR---------------------YTNAAYGCN TCNTCNGCNGGNGGNGCNGCNAGYCARGCNTCNGCNTCNYTNCCNACNYTNTCNTCNTCN TCNGARAARAARAARAARCARCCNCARTCNGCNAARGAYATHYTNGAYTCNYTNCARGGN MGNCCNAARAARAGYAARTCNGCNGGNAARAARACNATHCCNCCNYTNATGYTNGAYTCN YTNGGNMGNCCNATGATHCCNATGATGYTNGGNGAYATHACNYTNCAYAGYATGGGNGAR ATHGTNACNGAYMGNTCNAGYTTYCAYTGYCCNGARGCNATHTAYCCNGCNGGNTAYTGY ATHACNMGNGTNTAYATHAGYYTNCAYAARYTNAAYTCNAARTGYYTNTAYACNTGYAAR ATHTCNGARGGNGARAAYGARCCNYTNTTYGARATHGCNCCNGARGAYAGYTCNGAYATH GTNTTYMGNGCNAGYACNCCNTCNGARTGYCAYAGYYTNYTNYTNMGNGCNGTNAAYAAR TCNMGNGGNGCNGAYATHYTNCCNACNGAYACNCAYGGNCARGAYTTYTTYGGNYTNTCN CAYTCNGTNATHCARAAYYTNATHCARTCNATHCCNGGNGCNMGNAARTGYTCNMGNTAY AARTGGGTNAARTTYGARATHGAYAARTCNGARTCNAAYGARAAYTTYGCNATHGGNAAR AAYGAYCCNACNATHAGYTAYGARGCNTTYYTNAARCAYATHGCNGCNYTNACNCARGCN MGNCCNGGN---YTNGCNTCNCARATGGARAARTCNACNAGYYTNMGNTCNYTNYTNACN AARAGYTCN---ATGAAYTTYAAYGTNGARYTNGTNCAYGCNTCNGGNGGNMGNYTNGGN AARATHGTNCARATHGCNAAYGGNMGNACNGTNACNATHGAYACNCCNATGTGYACNYTN TTYACNAARGGNGGNAGYGTNCCNTAYYTNAGYYTNAAYATGYTNGARMGNGTNAARTTY ATHCCNGARATHGCNACNATGAGYATHAAYTCNTTYGTNGARCAYGTNGAYAGYYTNMGN CARAGYGGNAARMGNYTNGCNGARTTYACNTCNATGAARAAYAARYTNATHTTYTCNTCN YTNCAYGAYGCNAGYYTNCCNYTNCARTCNGGNAARAAYGAYAARTCNGGNGTNGCNGTN TGGGGNMGNGGNGGNAARACNATGYTNGAYCCNGCNACNTAYATGAARATHCARGARGCN ATHCARCCNGAYTGGYTNYTNGCNYTNAGYGAYGGNGAYACNGAYGTNGARAGYACNGAR AARMGNGCNGGNAARGCNGTNGAYMGNACNYTNGAYTTYYTNGAYGARATHGTNTCNGCN MGNGARAARTCNCARGTNYTNAARAGYTCNAGYYTNATHGGNGTNYTNGTNGGNGGNTTY AGYGARMGNCAYMGNCARMGNAGYGCNACNGARACNTCNGCNMGNCCNGTNCAYGGNTTY YTNYTNGARGGNTTYCARAARGGNAAYACNGARGARAGYYTNGTNGAYGAYGARTCNTTY CARAARATHYTNACNAARACNATHGGNTGYYTNCCNGARAAYAARCCNMGNYTNATGGAR ACNCCNTGGTCNCCNYTNCARGTNATHAARGCNGTNAARYTNGGNATHGAYGTNTTYTCN AGYGCNTAYCCNCAYACNYTNGCNGARAARGGNCAYGCNATGACNGARGAYTTYAGYYTN CCNCARACNCCNGCNCCNAARTCNGGNGARGGNGARAAYGGNGARGARGTNGAYACNAAY CARTCNGCNGTNATGGAYYTNAAYGAYAARAARTTYTTYGGNGAYTTYAGYCCNGTNYTN GARGGNTGYCAYTGYTAYACNTGYGCNACNTTYACNMGNTCNTAYATHCAYCAYYTNYTN AAYACNTCNGARYTNYTNGCNCAYGTNYTNYTNACNATHCAYAAYTTYGARCAYTAYTTY YTNTTYTTYCAYACNYTNMGNGARGCNATGAARAGYGAYMGNATHGGNGARYTNGARAAY AARYTNTCNMGNCAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNTCNTTYATHTAYCAYTCNGARATHTGYATGTTY YTNATHTGYYTNGTNATGTGYCCNGCNMGNTGGAAYTGYTTYGTNYTNATHAAYTGGTTY TTYYTNTGYCAYCCNCAYATGYTNAARAARTGGTAYGGNTAYAAYGARAGYAGYGTNGAR CARGAYAARGAYGAYCCNATHTTYGAYYTNGARGAYGAYGAYGTNGGNGAYGARTCNATG ATHGGNYTNGAYCCNTCNCCNTCNAARCCNGGNATGGTNGCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATHGAYMGNYTNTTYAAYTAYGARTCNATGGARCARYTNTCN TAYYTNYTNGAYCAYTAYMGNCARATGAARATHAGYATGTCNGGNMGNAAYGCNACNAAR CCNGAYAARTCNYTNGAYGTNGTNCARGGNTCNATGGTNGARGAYATHGTNGCNYTNYTN CARTCNTTYAARGARAGYTGYTCNAAYATHTAYAARCAYGGNGCNCAYCCNGAYACNTCN MGNGARGCNGGNCCNTCNMGNTCNGARCARAGYATHYTNAGYAARMGNCAYGCNYTNAAR TCNAARATHTAYGGNGARGTNGAYGTNAARAARTGYATHATHACNTCNATHGCNYTNTCN GAYYTNATHGTNGGNTTYTTYTGYYTNCCNGTNGARGCNTCNYTNTAYTTYATHTAYAGY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CCNYTNATHTTYAAYTGYCAYAARTGYCAYTCNACNTCNGCNTCNGARTTYTTY TTYMGNATHCAYYTNGCNAARCAYGAYGGNTTYAARCAYACNACNACNYTNTCNACNCAR GAYGGNYTNYTNATHTGYGCNCAYTGYAGYTAYATHGCNCAYAGYAAYATHGAYYTNGCN AAYCAYGTNACNAGYCAYGTNACNGAYMGNMGNTAYAARTGYTCNYTNTGYGAYMGNGAR AGYCAYCAYAARAARGAYATHYTNAAYCAYATHGAYAARAARCAYAARGGNGARGTNGAY GCNAARGTNYTNGAYMGNGARAARMGNAARGGNAARGARATGAARCAYAARGCNGTNAAY YTNAGYCCNATHATH------------------CARGCNCARGARCCNCCNACNAAYCAR CCNNNNNNNGTNNNNCARTGGGCNAGYNNNGTNNNNTCNTTYTCNTCNCARTAYNNNNNN NNNGGNTGGAGYGCNNNNCARATHYTNGGNNNNCCNAARGTNNNNCCNNNNNNNGGNGAY ATHCARGGNGCNTGGGCNNNNTCNNNNNNNAAYACNNNNCARTAYATHGARGTNGARTTY NNNNNNCCNATHMGNYTNTCNAGYGTNCAYATHTAYGARACNTAYAAYCCNGGNGCNGTN GTNAARYTNCARGGNMGNATGTCNAGYGGNCCNTGGACNYTNYTNTGGCARACNAAYMGN CCN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CARTTY CARCCNMGNATHGAYAGYCAYYTNTCNAARCARYTNGARGARGARATHGCNAAYTCNGGN GTNCCNCCNAGYAAYATHAGYGAYGTNGGNAGYTCNGAYGGNGTNGCNGAYGGNGTNACN AAYAGYAAYGGNAAYGTNAAYTCNAAYATHTGYGCNGCNTGYCARTGYCAYGCNTGYYTN AARCARAGYGGNCAYGTNATHTCNACNTCNYTNCCNYTNCARGTNCCNGTNTCNCCNCCN CCNGCNGARYTNAAYYTNTAYCCNCAYATHCAYGGNYTNCCN---CARMGNTAYATGTTY AGYTTYCCNTCNCCNYTNTTYCCNCCNATHAARYTNGCN--------------------- ------AGYACNCAYGAYCAYYTNTAYCAYGCNTAYAGYGAYTGGGAYAAYCCNMGNCCN GGNTCNYTNGCNTCNCARCAYCARCAYCARGCNCAYCCNMGNYTNTCNGGNYTNACNTCN GAYYTNYTNCCNCCNGCNCCNGTNGTNGAYGGNATGCCNGCNTTYAGYTTYGARGCNYTN AAYYTNAAYACNCAYAAYACNCARACNYTNACNAAYACNAGYAGYGCNTTYAARTCNGTN GCNGGNAARGGNAAYGARAAYTTYYTNTCNCCNAGYGTNAAYACNAGYAAYACNGARGGN AGYTCNGTNGAYCCNACNACNAARCCNYTNGAYTTYTCNTCNTTYYTNAARATHCCNCAR GCNTGYYTNAAYTCNTCNTCNTCNTCNYTNCCNYTNTTYACNTCNTCNGTNCCNTCNGCN GTNCCNTCNTCNGTNGTNTCNAGYCARYTNGTNACNACNTCNGTNTCNGCNTCNMGNAAY GGNTCNTGYCAYGGNCCNCCNTCNTCNMGNCCNGTNCCNYTNGGNGGNAAYGCNGTNACN AGYAARTGGGARAARACNCAYTCNYTNCARTGYAARAARTTYACNGCNCCNGGNCCNAAY AARTTYGCNYTNYTNAAYCARCARGGNGARCCNGTNAAYCCNTTYTCNCCNTTYTCNAAY TGYCCNCCNACNACNCARCARATHCCNGTNACNCARCCNCARGCNGCNTCNACNCARAGY TCNYTNTCNCCNMGNGTNTCNACNYTNCCNACNTCNTGYATHAAYGCNAAYACNAAYCCN ACNATHGTNAAYAAYATHGGNGTNGGNACNACNGCNCCNTGYGTNGAYTCNGARTGYAAR GTNCAYCAYGAYGAYAAYTGYGAYAGYGTNGAYGAYAGYTGYTCNGARMGNAGYTCNAGY ACNTCNTCNAAYCARAARGARGGNAARTAYTGYGAYTGYTGYTAYTGYGARTTYTTYGGN CAYAAYAAYCCNCARGGNGCNAARACNAGYCCNAAYTAYTTYGARATHAARGAYMGNYTN MGNGARAARYTNAARAARAARAAYGARACNAARCAYAARTCNACNAGYACNCCNGCNGTN GARACNAARAARGAYAARCAYCARAARGCNATGATGGARAARMGNGGNYTNGAYGARYTN YTNAGYTTYATHAAYGGNACNGAYGARAGY------ACNGCNAARGCNGCNAARMGNGCN MGNCARAARCARMGNAARATHGAYGARAARGCNMGNCARGARAAYGGNCCNMGNAARTGY GAYGAYAAYMGNCARCCNYTNATGGCNAARTCNYTNTCNAAYYTNYTNTAY--------- ---------AARTCNCARTCNGGNYTNGARGCNAAYAAYYTNGCNAARYTNCCNACNACN GAYCARGARMGNATHAARGARYTNCAYAARAARYTNACNCARYTNAARGARGARATGAAR CARGARACNACNMGNTCNTCNATGGTNATHGARTCNACNMGNCCNACNATHAAYGGNAAY AAYATHGAYMGNGTNYTNGAYATGATHCAYCARACNYTNAARCAYACNCARCCNGGNCAR TCNGCNGCNTCNCAYCARAAYAARTCNAAYCCNTCNCARGTNAARCCNCAYGTNGTNCAY YTNCARCARCCNACNAARCARGCNCCNCCNTCNCARCARCCNAAYCARCARTAYMGNCCN GCNGAYAARCARCARGTNYTNTCNCARCARAAYCARATHTCNCARACNCCNAARCCNTCN AARAAYYTNAARGCNACNGAYYTNCCNGTNAAYATHTCNAAYCAYATHAARTCNTCNGCN CARGCNGTNTCNGARGARAARAARTCNTCNTCNAAYGGNTCNAARATHGCNAGYTCNCCN TCNTCNAAYGGNGCNAARGGNTCNACNATGAARACNGARGCNTCNYTNTCNAARGAYTCN GCNTCNYTNGCNAAYGTNTCNTCNGCNACNACNYTNATGAGYAAYATGCARAAYCCNMGN AARTCNCCNTCNGARTCNCCNTCNTCNMGNGCNAARGCNCCNGTNGARCARGCNAARGCN GCNAARAAYAARAARAAYMGNAARAARTAYGARAAYGGNGAYATHCAYGAYCCNGAYGAR GTNTTYATGCCNMGNTCNGARTCNGARYTNGAYGGNACNGCNGAYGAYTTYGARMGNGAR YTNGARGARTTYAARMGNTTYTGYTTYGARACNGCNGARCCNAARGARAARMGNAARYTN GCNGTNAAYGTNAAYYTNAARGAYATHTTYAARAARAARACNTGGGGNTCNATGMGNTCN AARCCNACNGARGCNATGCCNAARCAYTCNYTNTTYGGNACNGCNYTNGARAAYGTNGAY MGNGARGCNYTNAARGAYATHGARGGNMGNTAYATHCCNGARGGNYTNGTNAARGARATH CCNAAYMGNTAYCCNYTNCCNCCNCAYATHMGNGAYCARATHNNNGGNMGNGAYTGYYTN GARACNTCNMGNAARGARYTNGCNGCNAARMGNGAYGCNYTNTCNCARGCNGAYAGYAAR YTNAARGTNAARTCNGARAAYGTNTTYGCNTTYAARACNGAYGGNYTNAARCCNGGNTCN AGYCAYGGNAGYATGCAYTCNAAYMGNCCNACNTGGYTNACNGARAARGAYYTNGARCAY GCNAARGAYATHAAYATHYTNGGNYTNGCNCARCAYGGNAGYTAYAAYMGNGAYAARTAY GGNAARAARCCNCARGTNCAYAAYTAYAGYYTNATHGGNGAYATHYTNGCNCCNAARATG GAYTTYAAYTCNCCNMGN---ACNATHGGNGARAARACNGGNCCNGARGGNACNAARTCN AAY---GTNATHTAYGGNCCNGGNMGNCARYTNCCNTAYGAYYTNATGGAY---AARTCN AAYCARAARAARAARAAYCARCCNCARAGYGTNATHGAYYTNCCNCCNAAYATHMGNCAY CARTTYGGNAGYMGNGTNTGYGAYACNYTNYTNTCNGAYCARGCNATHGTNACNYTNGCN YTNGARMGNCARAARACNAARATGGGNCCNCCNMGNCCNTCNAARAARCARAAYGTNGAR GGNYTNCCNGTNAAYYTNGARAAYACNTAYGARAGYYTNGGNCAYACNACNMGNTAYAAY GTNTGYCCNGGNATHTCNTCNGGNCAYAARATHAGYMGNACNAARGAYGARTTYAAYGAY GARGTNCAYAARMGNMGNGTNCCNAAYCCNGAYGARTAYMGNTAYCARMGNGAYGARYTN AGYATH---TGGGTNGARCARGAYGTNYTNMGNAARMGNATGGARCAYAARTGGAARTCN TAYTAYGARAAYATHCCNAARGCNGCNAARMGNCCNCCNCCNGCNAARCCNMGNCCNMGN CCN------AARCCNAARCARAARCCNAAYGARGTNACNCCNGGNGCNGAYGAYGARATG AAYATHGTNTTYGTNACNCCNCCNYTNACNCCNYTNCCNCCNGARAAYGARATHATHGAR YTNCCNAARAARTTYGARAARGAYGAYGARTTYTGGAGYTTYTAYGAYCARGTNGCNATH TTYGGNAAYTCNTGYGTNATHTAYYTNGTNGTNTCNAARMGNMGNATGMGNAAYGTNACN AAYTAYTTYATHGCNAGYYTNGCNGTNAGYGAYATHATGATHGCNGTNGTNTGYATHCCN TTYTCNTTYACNGCNAAYGTNYTNTTYGAYTAYTGGCCNTAYGGNAGYGGNYTNTGYCCN ATHYTNAAYTAYTTYCARACNGCNGTNGTNTTYCARAAYGCNTAYACNYTNCCNTTYYTN CARMGNYTNGGNAARMGNMGNTGYYTNCARATHGTNATHATHTGYTGGGTNYTNGCNTTY YTNACN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TAYGARYTNTTYGAR GAYGARATHAARACNYTNAARGGNTCNTTYCCNAGYCARACNAAYMGNTTYTGGATGACN GTNTCNGCNTCNGCNMGNCAYGTNTTYGARCARCARGAYCCNTGYTAYCCNAGYGTNATH YTNATGGCNTCNCAYAGYAARAAYCARCARYTNAAYATGTGYYTNGCNAARAARATHGCN TCNTCNTTYTCNTCNTCNTTYGGNATHAAYTCNTCNACNGAYGGNACNGAYGTNGARGAY TTYAARTAYATGGAYGCNGAYCARCARAARTGGCAYYTNGAYAARATHATGCARAARGCN TTYYTNCARGARGGNAARAARGCNTTYGTNATHAGYAAYGTNCAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GARAARTGGYTNTGYMGNGARYTNGGNAAR YTNGGNATHGAYTCNAAYGARGAYAGYGCNMGNTAYATHYTNTCNATGGARACNTCNAGY GAYYTNGARGARTAYATGYTNGARYTNYTNGAYGGNTCNAAYCCNAARGTNMGNTTYTTY YTNCARGARYTNAARGAYMGNCAYTCNGCNAARGGNAARAARGCNAAYTAYCARGTNTAY MGNAARGARGTNACNCCNGARTCNATHGARGTNAARTCNAARCARAAR------------ AAYAARGCNTTYTCNAAYCARTCNAARTCNAAYTCNAAYAARCCNGTNGTNAAYGGNAAY AARCCNGARAARGCNTCNGAYGTNAARGGNGAYAARAAYACNCAYTCNGAYACNCCNAAR GTNGGNGARATHGGNGTNGGNGCNAARAARAARACNAARTAYGTNCCNYTNTAYAGYAAR GARGGNCARGAYAARACNATHGTNCARYTNACNGGNMGNCAYAARTGYGARTGYCARGCN GCNAARCAYAARYTNATHAAYAAYTGYACNCAYTGYGGNMGNGTNGTNTGYGARCARGAR GGNGCNGGNCCNTGYGTNTTYTGYGGNGCNYTNGTNTGYTCNCCNGARGARATGGARATH YTNGAYMGNGGNACNAARAARTCNGARAARYTNMGNGARCARYTNATGMGN---GARAAY TCNAARCCNAARGGNYTNAGYGARGCNGGNCARTCNYTNYTNCCNATHGGNTTYAAYAAY CARTCNAARGARGARGARTCNMGNGCNYTNAARCAYMGNGAYAARYTNYTNGARTAYGAY MGNACNAGYGTNMGNMGNACNCARGTNATHGAYGAYGARTGYGAYTAYTAYGCNACNGAY TCNAAYMGNTGGYTNAARAARGARGAYMGNGARAARYTNMGNAARMGNGARGARGARYTN MGNGARTCNMGNCAYGGNTCNMGNMGNAAYMGNAARATHACNTTYGAYATHGCNGGNMGN GAYGTNMGNATHYTNGAYGCNGARGAYGAYACNGGNAARACNATGTAYAAYMGNGARGAY GCNATHATHCARGARGTNCAYTAYGGNAARTCNGCNTCNAAYAAYGCNGGNAAYGCNAAY ATHGTNAAYCCNYTNTTYGAYTTYGARCCNCCNATHTTYATGGAYACNGARCCNGTNCAR TGGGGNCCNGAYTCNGTNMGNCCNCCNCCNGTNGARCAYCAYAAYCCNCARATHTCNTCN MGNMGNATHCARGAYAARGARYTNCARGARATGAGYGAYGARGGNATGTGYYTNAGYATG CAYCARCCNTGGGCNTCNYTNYTNATHTGYGGNATHAARATGCAYGARGGNMGNACNTGG TAYACNCCNCAYMGNGGNMGNYTNTGGATHGCNGCNACNGCNAARGTNCCNGAYAARGAR GARATHAGYGAYYTNCARCARTTYTAYAARCAYTTYTAYTCNGGNTCNAARYTNAAYTTY CCNAARGAYTAYCCNACNGGNTGYYTNYTNGGNTGYGTNAAYGTNGAYGAYTGYYTNGAY CARGGNCARTAYMGNGAYAARTTYCCNGAYGGNGARTCNMGNTCNCCNTAYGTNTTYGTN TGYTCNAAYCCNTCNAARYTNYTNGTNAARTTYCCNATGAARGGNAARCAYAARATHTAY AARYTNGARTCNCAYATHCAYCAYGCNGCNAARAARGGNATHMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARYTNGTNGGNTTYTAYTTYGAYTCNTGYGTNTTYGAYYTNYTNGCNACN GGNGAYCARAAYTTYACNATHTCNGCNYTNAARGCNYTNCARGAYYTNYTNAARTAYCAR CCNTCNGCNTCNAARACNATHGGNAAYMGNACNTCNYTNGARTCNTAYGAYGARCARTAY GGNGGNGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------YTNACNGAYTTY GTNAGYACNCARGARTAYGARAARACNGTNYTNAAYGARAGYTCNYTNTTYATHATHAGY TGYGGNATGTTYACNGGNTTYTGYTAYTAYTGYCARTTYTTYATHMGNCARGAYTTYTAY YTNAGYTTYCCNTGYATHCARMGNMGNAARGTNTTYCARGTNMGNAGYGARATGMGNACN ATGGCNGARMGNATHGCNTGGCARACNYTNCAYGTNATHAARTAYTAYTAYATHYTNTAY TTYYTNTTYGGNTCNGTNCCNMGNACNTGGATHTGYACNTCNTTYGGNATHAGYGAYGAY ACNGAYYTNTAYCCNYTNGAYTCNYTNATHGGNYTNATGAAYYTNTCNYTNYTNTGGAAR TCNTAYYTNGTNTCNTTYGTNYTNACNTTYGTNYTNTCNTTYACNYTNGCNYTNACNMGN ATHTTYCARACNGARCARYTNGARTTYCCNGTNACNACNGTNATGGARCARTCNGAYGAR AARACNYTNCCNGAYGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------CARTGGMGNAARCCNGCNCCNTAYGGNAARCAY GAYCCNACNGAYGGNAAYTGGGGNCCNATGATHCCNCARMGNYTNAGYCAYATHATHTCN GAYGCNGTNTCNGGNGTNGTNATGTTYTCNYTNGTNTTYTTYYTNTAYAGYMGNGARGAR AGYGAYAARAARGCNYTNAAYTAYGTNTTYTTYAGYYTNTTYYTNGTNCAYACNATHCAY MGNGGNATHGTNCAYCCNYTNATHATGMGNTAYAARAGYGCNAARGTNTCNYTNGGNATH TGYATHGGNGGNGGNYTNCCNAAYGTNYTNTAYCAYTGGYTNATHGCNAAYCAYATHGGN GTNGCNAARTAYCAYGAYTCNTAYCCNTAYGAYCCNMGNTTYATHYTNGGNGTNYTNYTN TAYGTNACNGGNTTYGTNATHAAYMGNTGGGCNGAYTGGAARYTNMGNTCNYTNMGNAAR AARAARGGNGCNAARGARATHGTNGARAGYAARGGNTAYTAYATHCCNTAYGGNGGNTTY TTYAAYTAYGTNTCNTGYCCNAAYTAYTTYGGNGARYTNGTNCARTGGATHGGNTGGACN ATHGCNACNTGGTCNYTNTCNGGNTTYGTNTGGGCNTGYTTYGGNGCNGCNACNTTYTTY GCNMGNTCNMGNCAYAAYCAYCARTGGTAYAARGAYCAYTTYGARGAYTAYCCNTCNCAY MGNAARGCNYTNATHCCNTTYGTNTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GGNTTYATHYTNCAYCCNTCNGGNACNCAYTAYATGCCNATHTCN GTNCAYAAYAGYAAYATHTCNGGNYTNTTYGAYAAYAAYGGNGAYCARGARGGNATGCCN GTNTTYCAYCCNATHAGYATHCCNGTNCAYTTYMGNMGNCCNGTNATH------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGCCNYTNYTNAARATHGARACNAAYYTNCCNAARGAYCARATHCCN GARAARTTYYTNYTNGARGCNACNGAYATGATHTCNTCNGARYTNGGNAARCCNGCNTCN TAYGTNAGYATHCARGTNTGYCCNGAYCARGTNATGAGYTTYGGNGGNACNACNGARCCN TGYGCNAAYATHACNYTNAAYTGYATHGGNGTNGTNGGNCCNGARAARAAYMGNAARYTN GCNCCNGTNYTNTCNAARTTYATHGARCARAARYTNGCNATHAARCARGARMGNTTYTAY ATHAAYATHTTY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYCARGCNCCNACNAAYYTNCCNGCNTCNGCNYTNGCNTCNGGNYTN GTNMGNGCNTGGGAYYTNTAYGAYAAYCCNAARGCNGTNATHGTNTTYATHGTNAGYAAY TTYGARMGNAAYGTNYTNGAYCARMGNGCNYTNGARTTYGGNGTNTAYAARMGNAAYCCN CARATHMGNGTNYTNMGNAARACNATGYTNGAYGTNGARGARMGNGGNAGYYTNGAYGAR GARAGYMGNYTNTTYGTNGAYGGNGAYGARGTNGCNGTNYTNTAYYTNMGNCAYGGNTAY ACNGTNGAYAAYTAYCCNTCNCARAARGARTGGGAYGGNMGNYTNAARATGGARYTNTCN MGNGCNATHAARTGYCCNTCNGTNCARTAYCARYTNGCNGGNGCNAARAARATHCARCAR GARYTNACNMGNCCNGGNGCNYTNGARMGNTTYATHGAYGAYCCNAAYATHATHAARGAR YTNMGNGCNACNTTYGCNGAYCARTAYAGYYTNGAYYTNGGNCCNGARGGNGAYCARGCN GTNGCNYTNGGNATHGCNTCNCCNGAYAARTTYGTNYTNAARCCNCARMGNGARGGNGGN GGNCAYAAYYTNTAYGGNGARAGYATHGTNAARTTYYTNACNGARCAYAARGARAGYAAR GARMGNAAYGCNTAYATHYTNATGGARMGNATHTTYCCNATGCARCARCARAAYTAYYTN TTYAARGARGGNGTNCCNTTYTGYYTNTCNAAYGTNGTNAGYGARYTNGGNATHTAYGGN GTNTAYATHGGNTCNAGYGAYYTNGARGARYTNGARAAYAARGARGGNGGNCAYATGATG MGNACNAARATHGCNGGNACNGAYGARGGNGGNATHGTNGCNGGNTTYGCNGTNYTNGAY ACNCCNYTNATH------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ACNATHGAYTGYYTNYTNAARAAYGTNCCN GAYYTNMGNGARAAYYTNGARMGNGGNATHGAYGTNATHGARTTYGGNTGYGGNAGYGCN TAYYTNYTNTCNCARYTNGCNACNATGTTYCCNAARAGYAAYTTYACNGCNACNGAYGTN AAYCCNGCNTTYYTNGARTGYGTNAARAARMGNTGYTGYCAYYTNTCNAAYGTNAARTAY GAYGTNGTNGAYYTNTAYGCNATHCCNGARATHGCNGAYAARCARTAYGAYTTYGTNTAY GCNCAYGAYGTNATHCAYGAYYTNCCNAARCCNGTNGARGCNYTNAARGGNATHMGNMGN GTNYTNAARGARCCNAAYGGNATHTGYGGNATHGTNGAYTAYGCNGGNACNGGNAGYCAY CARAARGAYGTNGGNGAYATHTTYGCNGCNCAYATHTAYGCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAR CCNCCNCCNTCNTAYGAYTCNYTNTAYGGNMGNGTNAARGCNGCNAARACNTCNTCNGCN GGNCAYGTNGAYTTYTTYAARACNTTYYTNACNATHATHYTNTCNACNATHGGNTTYACN ATHATGYTNGCNATHTTYATGGCNATHCCNGTNTCNATGATHGTNATGGGNGCNATHTAY ATHGAYGAYTGYGAYGCNGARMGNATGATHCCNATHTAYYTNATHGTNGCNGGNAGYTTY GGNTGYGCNAARAAYATHTTYAGYYTNATHCARMGNTGYMGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYTCNYTNCCNCCNGCNTAYGAYCARYTNCCNGCNGCNAGY AAYCCNAARGTNGGNAAYYTNATHGAYYTNAGYGAYGAYCCNTCNCCNGCNGAYAAYTCN ATHAAYTCNCARYTNGCNGGNATGACNYTNAAYTCNACNACNGCNACNAAYGCNGCNGCN CCNCCNCCNACNMGNGGNGAYGAYGAYTTYGAYATGTTYGCNCARTCNMGNCARTCNTTY GAYCARAAYMGNCARGCNGTNTCNCARTCNAAYTAYAAYAAYCARCAYCCNGAYACNTTY AGYGGNGGNYTNGGNCARGCNGTNAGYGCNMGNACNAAYGARGAYACNYTNAARYTNCAR GARAARGAYTCNGAYTAYGAYGARATGGARCARTGGYTNGCNACNCAYGGNGGNCCNGGN TCNGAYTCNAARACNCARGARCCNATHACNAGYTCNGARTTYGAYMGNTTYYTNACNGAR MGNGCNACNGCNTCNGARGCNYTNCCNAGYATHTCNGCNCARACNGGNMGNTCNACNMGN ACNYTNCARAARAARGAYGAYGAYGARAAYCCNYTNTTYGCNYTNAARGCNGCNAGYACN AARTCNGTNAAYCCNTTYYTNCCNGARMGNCCNGCNAAYCCNCCNCCNYTNAGYTCNGCN MGNACNTCNTCNYTNMGNGCNAARGCNAAYGARGARAAYAAYGARGARTCNYTNTCNGCN CCNCCNAARAGYYTNAAYCCNTTYYTNTCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ACNYTNTCNATHAARTTYYTNYTNGAR AARGTNGARGGNGTNMGNAARGTNYTNATHGTNGAYYTNGAYGCNCAYCARGGNAAYGGN CAYGCNMGNGAYTTYATGGGNGAYGARMGNGTNTAYATHYTNGAYGTNTAYAAYMGNGAY ATHTAYCCNCAYGAYGGNTTYGCNAARMGNGCNATHCARMGNAARGTNGARATHMGNTCN TTYACNGARACNGARGARTAYYTNCARATHGTNMGNMGNCAYGTNGARGGNGCNYTNAAY GARTTYGARCCNAGYGTNGTNGTNTAYAAYGCNGGNACNGAYATHYTNGAYGGNGAYCCN YTNGGNYTNYTNGCNATHTCNTCNCARGGNATH--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATHAARATGGCNGGNCARACNGGNGCNTCNTTYCARATHGGNAAYAAYCCNYTNGAR GCNGCNTAYMGNGCNGAYGTNATHATHACNGAYTCNTGGTTYMGNGCNGGNCARGGNGAR GARMGN---GARAARMGNYTNAAYGAYTTYCARGGNTAYCARGTNAAYMGNAARATHYTN AARGARGCNGGNGGNAAYTGGGTNTTYATGCAYTGYYTNCCNCAYTCNGARGARGARGTN AARGAYGAYGTNTTYTAYGGNGAYGARTCNYTNGTNTGGCARATGTCNGARAAYMGNATH TGGACNATHATGTCNYTNATHYTNAAYCARYTNCARGTNTAYACNCCNAAYATHCCNATG CCNAARTAYGTNMGNGGNATGTCNGARGGNTCNGCNTCNCCNAARMGNCCNMGNYTNGAY TTYGAYGAYAAYTCNAARGARGAYYTNCAYGARAARYTNAGYAARAAYMGNGAYCARGAY GAYCARGGNAGYTAYAGYAAYTCNMGNAARMGNMGNCCNGARGCNGGNGARGAYGARGAY GAYYTNAARGAYTGYGAYGAYATGAARTCNAARAAYGCNGTNGTNGAYGCNGCNMGNMGN GARCAYACNYTNGTNATGMGNYTNACNAAYAARGARCARGARGTNCARGARTGYATGAAY CARATHCARGARATGAARCAR---------------------------------CARYTN GAYCCNGCNATHAAYYTN------------GTNTTYCARMGNATG--------------- ---------------------------------------------------TCNAARGAR ATGGARGARCAYAARGARAARYTNAARCARAARCARAAYGARYTNAAYGCNTGGAARTTY ACNCCNGAYAGYCARACNGGNATGMGNYTNATGGGNAARTGYMGNATGYTNYTNCARGAR AAYGGNGARYTNGGNAARATGATHTCNTCNGGNMGNACNGCNMGNYTNGARGGNGARATH TCNYTNCAYAARGCNYTNGTNGCNGARATGAARAARAAYCARAARGARYTNGAYGARTTY GTNGGNGARYTNGARGARGAYGTNGARGGNATGCARGGNATGATHTTYATGYTNCARCAR CARYTNAARGARGCNMGNGARCARATHACNMGNYTNCARCARGARAAYGARCARYTNMGN ACNYTNGARYTNCCNTCNGARCCNGARCCNGGNGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ACNMGNCAY GGNGAYTCNTAYTGYGGNAARYTNMGNTCNAAYYTNYTNGGNACNCARTTYACNYTNTTY GAYCAYGGNGAYAAYCCNAARAARAGYGGNCCNCARGCNGCNMGNCARGARYTNGTNGCN ATGGCNTAYGARACNAAYGTNYTNGGNTTYAARGGNCCNMGNAARATGACNATHATHATH CCNGGNATGACNAGYGARCAYACNMGNGTNAAYATHAARCCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARACNAARGAYCARATGTTYGAYAAYYTNAAYGARYTNGAY GAYAAYYTNACNAARGCNCARAGYYTNGCNATGGTNTTYTGYGTNTAYCARYTNTTYTAY AAYTTYACNAARGAYGCNCCNAARGTNAARCARYTNYTNACNTCNACNACNTGGTCNTCN YTNAARTCNAAYTTYGGNMGNGARMGNAGYGARGARATHATHTCNGCNGCNATHCAYTAY YTNAAYACNATHGAYTTYGAYATHGARAGYTGYTGYGGNGAYAARTTYGTNTGYMGNGAY GAYGAYTGYYTNTAYYTNACNCARAAYAARATHAGYATHYTNACNAARATGATHACNGCN GARAAYGCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATHAARACNATGYTNCARGARATHGGN MGNGGNGTNCCNGTNCAYGGNTTYAARGTNTTYYTNCARYTNATHTCNCARACNAARGCN GARACNGGNYTNGAYAAYATHCCNCARTAYYTNGAYATGYTNAARATGCAYCARAAYAGY CCNGGNAARTGYYTNTCNYTNYTNTGGGCNYTNGGNCARTGYGGNAAYAARCAYTTYCAY YTNGGNYTNMGNGTNTGGYTNGARYTNATGYTNCCNGCNYTNGARATHMGNCARGTNGCN CAYTTYCCNGTNGAYTAYYTNGARAAYYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARGTNTTYGAYCAR MGNMGNTGGAAYTGYGTNAGYMGNCCNCARTAYAARACNTCNTGYGGNATHTCNTCNGTN GTNTCNTGYTGGAAYTTYYTNTAYTCNACNYTNGGNCAYGGNCAYYTNYTNCCNYTNAGY CARGARGAYGCNATGATHATHYTNGGNTTYGAYACNCCNTTYGARAAYATHAARTTYGGN CCNACNACNGGNAAYATHACNYTNATGMGNTGGTTYCARAARYTNAAYAGYCAYTTYCAR GTNGAYGGNMGNTGYCAYTTYATGTAYAARCCNTGYGGNMGNAAYMGNACNCCNGGNYTN ACNCARGARATGGCNYTNAARAARYTNAARTCNGGNYTNMGNGAYAARAARACNGCNTTY ATHTAYCAYTGYCAYAAYCAYTAYTGYTGYCCNATHGGNTTYGARGARTCNGCNTGYTAY GCNYTNGAYGCNTAYMGNGARAARYTNTCNGARGARTCNGTNGARAARACNTGGATHYTN ATHGGNGAYACNAGYMGNAARCAYGGNCCNTTYCAYTGYAARAGYTGGGARGARATHTGY ACNGAYYTNAAYTGYGARAGYCCNGARTTYTAYAAYATHMGNCARTCNTGGAARGGNGTN CARAARMGNAARACN---AARAARATHGGNGGNAAYYTNCAYTGYATHYTNTCNTTYCAR TCNTGYCARCCNAAYATGAAYAAYCARAAYCARAAYAARGCNAGYATGCARCARTCNTTY YTNCAYCCNCCNCCNCCNCCNTCNTCN------------------TCNATHTCNCARCAY YTNMGNGARGCNGARGARMGNYTNAAYGARTTYGGNAGYGTNATHTCNAAYTTYACNAAY CAYAAYCCNCARGAYGARATHTTYGARCARATHAARCAYATGAARAAYGARATHGAYGCN TCNYTNAARAARCAYGARAAYGCNTCNTCNAAYAAYCARAARACNGTNCARGARYTNGAR GCNGARAARGARGGNYTNTCNTTYAARATHAAYATGGAYAAYAARGGNATHGAYYTNACN AARGAYGARYTNAGYCAYYTNATGAARGARAARYTNCARYTNAARAAYGTNCCNGAYAGY GARAARGCN---YTN---AARGTNAARCARYTNGARGCNGARGAYATGATGTTYMGNAAR CAYTTYGGNATGGARATHMGNAARATHAARGGNGGNTGYYTNCARGTNGCNTTYAGYCAR ATHGAYCARAARCARCCNAAYTCNYTNTTYYTNTTYTCNYTNAARTTYGAYGARAAYCAY CARTAYGTNGTNTCNGAYTGYAARCCNCCNATHTCNGAYYTNAARGAYYTNGTNCAYAAY YTNAAYATGGAYAAYGAYTTYCARAARTTYATHYTNACNATGMGNAARMGNTTY------ ---AAYGTNGGNCARAARACNGCNCARGAYTTYCARAAYGTNTTYGGNCARGAYMGNGTN GCNTTYTTYAARGGNAAYATHACNAGYCARGARGAYATGAAYAGYGTNTTYAARTCNACN AARGAYAARTTYGGNGGNYTNGAYATHGTNATHAAYAAYGCNGGNYTNGGNGGNGARGCN GAYTGGGARMGNACNATHGAYATHAAYGTNAARGGNTCNATHMGNGGNACNYTNYTNGCN ATHGAYCAYYTNMGNAARGAYAARGGNGGNMGNGGNGGNGTNATHGTNAAYATHTCNAGY ATGGCNGGNATHAAYCCNAAYCCNTGYTCNCCNACNTAYTGYGCNTCNAARAGYGCNYTN ATHCARTAYTCNYTNAGYTGGGCNMGNAAYTCNGARYTNYTNGCNAAYGGNGTNMGNATH AAYGTNYTNGCNCCNGCNTTYGTNGAYACNCCNYTNATGTCNACNATH------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNAARMGNMGNTAYAGYGAYGTNAAR---GARGAYYTNTAYMGNGGNCCNCARGAY TTYATGGARGCNGGNGTNMGNGGNTTYYTNATHACNTCNATHCCNGAYMGNGARGARCAY TCNATHGAYGARACNGTNAARGTNYTNMGNAARACNTGYGTNAARYTNTAYGGNGGNATH AARCCNYTNAARMGNGARGAYGCNTCNTTYGCNAARGGNTAYATHATGGTNGAYTTYATG AGYCCNGARAAYGTNGTNTGYYTNCCNCAYCCNGAYGCNGAYAARGTNGTNGARGARGAR AARGCNAARACNGCNGARGARACNACNAARGARGARGGNAARGAYAAYGARGARATGGAR GCNGARGAYAARCCNGARGARGARACN------------------AARCARGARGARGGN GAYACNGARGCNGAR---------AARGAYAARACNGARGGNGAYGCNGARAARACNAAR GARGARGGNAARGARGAYAARGCNAARGARGARAARGARAARGARGARAARAARAARAAR GARGAYATGMGNMGN--------------------------------------------- ---------------------------------------------------------AAR MGNGAYGARGAYMGNAARCCNYTNATGYTNGCNCCNTAYAARTTYAARGCNTAYMGNACN GARYTNMGNAAYATHATGTTYYTNAARTCNGAYATHCCNGAYCCNGTNGARGTNGTNAAY GCNTGYTTYGAYATGATGYTNGAYMGNAARCCNYTNTAYACNGAYTGYGTNCAYCARYTN YTNCCNGTNCARGGNGTNTGYGAYAAYGAYTAYAARCARYTNGARATHATGTGYMGNMGN GTNYTNGTNCCNTAYGTNGGNGARCAYYTNGARGARGCNCCNAGYTTYGGNGTNYTNYTN ATHAAYAARATGTGYGARCCNGGNGCNGARGTNYTNYTNGARGTNGTNMGNAGYGTNATH TGGTGYYTNAAYCCNAAYGCNTGGCARTGYTCNCCNTGGGCNGARCCNGAYGTNGTNATH CAYATHGARATHATHGGNAGYAARATHATHYTNAGYGCNATGCCNCAYTAYATGAARTAY MGNCARTAYAGYCCNTTYGCNGTNCAYGARYTNGGNCCNGGNMGNTCNGARGAYGARGAR YTNYTNYTNAARGARATHGARAAYAAYMGNGGNGAYMGNGAYMGNGGNGGNMGNGGNGGN AARMGNAARGAYGGNMGNAARGAYMGNGAYGAYAARAARAARCCNAARGAYAARGAYGAR AARAARGARGGNGGNGARGARGGNAGYAARGARAAYGARAAYACNAAYGARGARAAYAAR ---------GARCARAARGARGARGTNAARGARGAYAARCCNAARGARACNAARGARGAR ------------------------------------------------------------ ---------------------------------------------GARMGNYTNMGNMGN ATHAARAARAARACNGARGARAAYATHYTNGTNYTNYTNTCNMGNATHTCNGTNAARACN AAYCCNTCNCCNTAYYTNCCNAARTAYGAYATHYTNTCNACNYTNACNAARTAYGTNGCN GTNGTNCCNATHCCNYTNCARMGNTGYYTNMGNATHATHTTYMGNGTNTTYCAYAAYCCN CAYTGYTTYGARTCNGTNYTNYTNGARCARGCNCCNGCNYTNATHGTNAARAAYYTNATH YTNGAYCARGARGGNAARTTYCCNTCNGTNYTNTTYAARGAYCARAARGAYGARAARCAR CAYGGNCAYGARCAYMGNGARATHAAYTTYGAYGARATHATHGCNTCNTCNCARAGYTCN GARACNCCNTCNGAYTTYGARYTNCARATHCARTTYGARTTYGGNGGNGAYGCNTAYAGY AAYATGCAYCARMGNAGYTTYCAYTCNGAYYTNTTYCARCCNAAYTTYTCNTAYMGNAGY AARTCNYTNAGYCCNGGNGAYAAYTCNTTYYTNTAYTCNCARATGCCNTCNGARGAYYTN ACNMGNATHMGNATHCAY---AARGGNATHAAYYTNATGAARGTNATHACNTCNYTNGCN YTNTCNMGNTAYGGNGAYGGNGARATHCARMGNYTNTGGTCNMGNGGNACNGARTCNGAR AARYTNATGTGYGCNATHAGYYTNYTNAAYATGCCNATHGGNTGYGGNCCNYTNCAYMGN CAYCARATHATHTTYAARCAYGGNGCNYTNCARCARGTNATHCCNYTNYTNTTYTGYAAR GARGCNCCNCAYGTNMGNGARAGYATHGTNACNGCNYTNAGYYTNYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATHCCNCCNYTNCCNCARGGNTGGGARGCNMGNTGG GAYCCNGGNCARGGNMGNTAYTTYTTYATHAAYCAYCARACNAARAARACNCARTGGGAY GAYCCNMGNTAYCARCCNCAYCARCCNCARCCNGCNGCNGCNTCNTCNGGNCARACNMGN GCNGCNTCNMGNCARACNTCNAAYCARCARCARGARTCNAGYATGTCNGARGARGTNGAY CARGCNYTNGTN---GAYAARYTNCAYMGNGAYTTYCCNAAYACNACNAARGCNYTNATH TCNGAYATHYTNGTNGGNTGYTAYAAYAAYGARMGNGARGCNMGNGARCARYTNGARGAY YTNGGNTTYTCNGAYAAYCARTCNCCNACNMGNACNTCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AARACNTCNGTNGARTGGGARCCNYTNGCNCCNYTNGGNCCN CCNGCNGCNTTYCAYGTNGGNTGYYTNATHMGNGGNAAYYTNTAYATHCAYGGNGGNATH TCNGAYACNAARTCNAAYCARCCNTCNAAYCARYTNTAYAARYTNAAYYTNCAYTCNAAY YTNTGGCARTGYATHMGNAGYACNGGNAGYCCNACNYTNAGYCAYCAYGCNTGYGTNGTN GCNGARGAYMGNTAYATGATHYTNATHGGNGGNTGGAAYGGNAARMGNMGNAGYGCNGAY GTNCAYGTNTAYGAYGTNCARGARGAYAARTGGYTNCCNGTNAARCARACNGGNTTYCCN GAYGGNGCNGGNYTNAGYTCNCAYACNGCNTGYATGYTNATHAAYGGNGAYATHYTNATH GTNGGNMGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARTTYGARGCNCARGARGAYGCNAARATHGCNGCNYTNAARAAR CCNCARCCNGGNTCNMGNCARCARCCNATGGARGGNYTNATHYTNAARTTYACNAAYGTN GTNAARGGNTAYCARTAYMGNTGGYTNGTNYTNGAYCCNGAYTCNGGNATGYTNGARTAY TTYGARAARGARGARCAYAARAARCARMGNCCNMGNGGNTCNGTNCAYYTNGCNGCNGCN GTNGTNTCNCCNTCNGARGARGAYTCNCARACNTTYATHGTNAAYGCNGCNAAYGGNGAR ATHTAYAARYTNMGNGCNTCNGAYGCNMGNGAYMGNCARYTNTGGGTNGAYMGNATHMGN TCNACNGCNGARCAYCAYACNGCNAAYATGACNCARTTYCCNCARCAYTCNCCNAARYTN ATGMGNACNGAYTCNTTYAAYTCNCARTCNAAYMGNMGNAAYGAYTCNGGNMGNMGNACN MGNGGNTCNATGGARAGYYTNCCNATHAAYAARMGNTCNCCNMGNGAYGARACNTTYCAR GARGTNAARGARTTYCAYYTNGAYGCNGARGAYTGYYTNMGNAAYYTNGARGAYAARATH TCNACNYTNTCNCCNTCNGGNGAYCAYATHAAYTCNYTNGAYTCNGARYTNYTNYTNYTN AARGCNACNTCNGCNGCNACNYTNMGNTGYGTNCARGAYTGYATHTCNYTNYTNCARAAR ACNCARTCNTCNCARTCNAGYCCNMGNAGYCCNYTNGCNAAYGAYCARCCNMGNYTNAGY GTNACNGARACNGAYGGNAAYACNGAYTAYCARGCNAAYYTNCCNAARGARGARGARGAR GTNYTNGAYGARGARGTNTAYGARGAYAARGAYYTNGARGGNGTNGARGARCAYAARTCN ATHATHYTNCAYYTNYTNTCNCARYTNAARYTNGGNATGGAYYTNACNAARGTNGTNYTN CCNACNTTYATHYTNGARMGNMGNTCNYTNYTNGARATGTTYGCNGAYTGYATGGCNCAY CCNGAYGCNTTYYTNAARATHCCNGAYATHCARGAYCCNGARGGNMGNATGYTNGCNGTN YTNGARTGGTAYYTNACNTCNTTYCAYAAYGGNMGNAARGGNACNATHGCNAARAARCCN TAYAAYCCNATHATHGGNGARACNTTYCAYTGYTCNTGGYTNAGYTAYATHGCNGARCAR GTNTCNCAYCAYCCNCCNATHTCNGCNTTYTAYTTYGARTGYCCNAGYAARAARGTNAAR ATHAAYGCNTCNATHTAYACNAARTCNAARTTYATGGGNATGTCNATHGGNGTNTCNATG GTNGGNAARGTNMGNYTNMGNYTNGARGARTTYGAYGARGAYTAYGTNTTYAGYYTNCCN AGYGCNTAYGCNMGNTCNATHYTNACNGTNCCNTGGGTNGARYTNGGNGAYAARGTNTCN YTNACNTGYGAYAARACNGGNTAYCARGCNAAYATHATHTTYCAYACNAARCCNTTYTAY GGNGGNAARYTNCAYCAYGTNACNGCNGAYGCNAARAAYACNAARACNGGNGARAGYATH TGYAARGTNCARGGNCARTGGAAYGGNGTNATGGAYTTYACNTTYGCNACNGGNGAYACN CARTCNGTNGAYGTNTCNCARYTNTAYGTNACNMGNAARTCNGTNMGNCCNATHGARAAR CARGARGARCAYGARTCNMGNMGNYTNTGGCARCAYGTNTCNACNGCNYTNAARYTNAAY GAYATHAAYACNGCNACNGARCAYAARAARGGNYTNGARGARYTNCARMGNGARGGNGAR MGNCAYMGNAARTCNATGGAYYTNCCNTAYGTNGGNAARTTYTTYGAYAAYATHGAYGGN ACNTGGACNCAYAARAGYYTNCCNAARATHTTYATGCARGARAARAAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYATHCCNTTYGAYATHATG GGNATHAARYTNYTNTGGTGGACNTGGCAYGAYGAYGAYCCNAAYATHTAYGAYMGNCAY TAYTGGGTNCCNTGGACNTCNTAYTAYTTYCAYGCNGCNTTYGCNTCNTCNTTYTCNATH GTNTTYTTYGGNTCNAARACNYTNTTYTGYTCNMGNGCNYTNAARTTYCARAGYAGYGGN TTYATHYTNGARYTNYTNATHGTNATHATGACNGGNYTNTTYTCNATGCCNYTNGGNGTN YTNCARTTYATHCCNATHTAYCAYCCNYTNCAYGAYTCNYTNGGNATHCAYTCNGARGCN TGYGTNYTNYTNTTYYTNGCNTTYTTYGCNYTNATHGTNTGGTGYTCNGAYMGNMGNCCN TTYGAYTTYGCNMGNTTYAARGGNGGNAGYYTNTTYGGNYTNATGATGYTNGTNGTNATH YTNCAYTAYTCNTTYTAYGCNTTYYTNGTNTTYACNGCNAAYCCNAGYAARATHMGNTCN ATHGGNYTNCAYCARCCNGTNGGNCCNTGYAAYAARCARGTNAAYGTNCARACNGCNTTY GGNCAYGTNYTNAARAARAGYCAYTAYYTNTGYYTNAARAAYTTYTCNGARGAYTAYTTY ACNYTNGAYTGYYTNAARAARCCNCCNTCNGAYAARACNGARTGGTAYACNATHTGYGGN ACNCCNTTYCCNAAYCAYAARGARTAYATGGTNGTNGTNTGYGCNTTYTGYACNYTNGGN YTNTTYTGGTTYTAYCARGCNYTNTGYMGNTCNGGNGCNCARCCNCARATHAAYTCNAAY AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYTCNTCNGAYTCNGAYTCNTAYAARTCNGAYGAYTCNACNACNAARGAYGGN AARAARAARGARAAYCCNCAYCCNGAYATHYTNGGNTCNAARTCNGARAGYAARGAYAAR GARATHATGTCNAAR------------------GCNGGNMGNAGYMGNTCNMGNTCNGAY TCNMGNTCNAARTCNMGNTCNMGNTCNCCNTCN---CCNAARMGNMGNMGNTCNTCNGAR AARAGYMGNMGNTCNMGNTCNMGNTCNMGNGAYMGNMGNCAYMGNMGNGAYMGNAARCAY MGNTCNCAYMGNTCNMGNTCNAARGARMGNMGNMGNTCNMGNGAYMGNCAYMGNCAYAAR AARGAYMGNMGNMGNAGYMGNAGYMGNAGYMGNAGYMGNGAYMGNAARGAYMGNCAYTAY AGYMGNAARAGY---AGYMGNGAYMGNGAYMGNMGNMGNMGN------------AGYMGN AGYMGNGAYMGN---------------------MGNGAYAGYMGNAGYCCNAGYCCNCAY GAYGGNAAR------GTNATHAARTTYGGNAAYAARGTNATHAARCCNGGNGCNAGYTTY GGNMGNCCN------TCNTCNAAYTTYTCNAARCCNGTNACNTTYAARGARAARATGMGN CARCARYTNATHAARGCNATHGARGAYGGNGCNGAYACNAAYGARGTNYTNGCNAAYAAR GGNGGNTCNACNATHTGYACNCARAGYGCNGGN---GTNCARCARCARGCNATHCCNAAR CCNAARGGNCCNCCNGTNCCNYTNATGGAYACNATHGTN---TCNACNGCNAGYYTNGCN TCNATGACNGTNACNGCNTCNGARGCNGCNATGCARTCNATGYTNGCNYTNCARAARGAR GCNACNGARAARACNGGNATHGARATHCCNAARTAYTAYAAYCCNGCNGCNATHAAYCCN ATGAARTAYGCNGARCARGTNCARAARMGNAARYTNYTNTGGTCNAARGCNAARGAYAAR GAYGTNAAYTCNCARTGGCAYGCNACNAGYYTNTCNGGNGAYGCNGAYGAYAARTCNAAR GARAARTTYMGNAARYTNATGGGNATHAARAAYGAYCCNGCNAGYGCNGCNCCNAARGAR GGNGARAAR---------------GARGARAARCARAARCARYTNTTYGAYCARYTNAAY AARGARTAYGARTTYGCNMGNATGACNACNCAYACNCAYMGNGGNATHGGNYTNGGNTTY AGYTCNTCNTCNGGNTAYCCNCARCCNACNTCNATGGCNCCNATHCCNGARGAYAAYCAR GARAARCCNCCN---CCNMGNGAYGAYGARGAYYTNGAYAAYTTYTCNAGYGGNAAY--- ATGGCNCCNGTNTCNTTYGGNTCNGAYTCNAGYGAYGARAAYGAYGARAAYTAYCCNGAY ACNGCNGGNTAYACNYTNYTNCCNCARGARCCNGGNGCNGAYGAYAGYGAYGAYGAYMGN GAYAAYGAYAAYGARCCNGARACNATHGAYACNACNGGNATHGTNGCNGGN--------- ---------------------------------------CAYYTNCCNGARGARGTNGTN CARTCNGARGGNGGNGTNYTNGCNCCNACNGTNGTNGCNTCNAGYACNTCNYTNCAYCCN GARTTYYTNGCNAARTTYCCNGAYGGNAARGTNCCNTCNTAYATGCARGTNCCNGAYATH CCNYTNGAYAGYAARGAYYTNYTNTGGAAYAARMGNMGNYTNGARCARAGYTCN---GCN YTNGAYACNGCNGARGARAARAAYATHATHAARGCNATGTCNGGNTTYTCNYTNCCNYTN GARAAYGTNCCNGAYTGGGCNAARAAYATGTCNGARGAYCARTGGAAY---AAYGTNATH TCNCARCARATHGGNTCNTCNCARCCNGARTCNGTNAARYTNTGYCARAGYAGYCARAGY TCNAAYACNGARGAYTGGATHGCNGARTTYCCNGAY------------------------ ------------------------------------------AAYGTNMGNMGNTTYGGN AARAGYTTYATGAARAARGAYGGNGTNGTNTCNGGNYTNGTNAARATHYTNCARMGNTAY GAYATHGTNYTNGTNCARGARGTNMGNGAYTCNTCNGARACNTCNYTNCAYGAYYTNAAR AAYAARYTNGTNGCNGCN---GAYAAYTGGGAYTTYGTNGTNAGYGARCCNYTNGGNMGN TCNCAY---TAYAARGARCARTAYGCNTAYTTYTAYAARCCNAGYTCNGTNAARGTNATH MGNTCNTAYCARGTNGCNGAYTCN---GCNGAYGTNTAYGARMGNGARCCNTTYGCNGTN GAYATHGARTAYMGNTCNYTNTCNCARTCNTCNAAYCAYMGNGTNGTNYTNYTNGGNATH CAYGCNAARCCNAARGAYGTNGARGCNGARYTNMGNGARYTNTCNAARACNGTNAARTCN GTNGCNTCNGTNTTYCCNGAYGCNCARGCNGTNGTNTCNYTNGGNGAYTTYAAYGCNGAY TGYAGYTAYYTNAGYMGNACNGCNCARAGYGGNYTNGARATHTTY---AGYAGYCCNGAY TTYGTNAGYYTNATHCCNGAYGAYGCNGAYTCNACNGTNTCNMGNAAYACNGAYTGYGCN TAYGAYMGNGTNGTNGTNTAYAGYTGYGAYMGNMGNGTNTTYGAYGTNAARGTNTTYAAY TTYGARAAYTTYYTNAAYATHGARGARGAYGARGCNMGNAARATHAGYGAYCAYTAYCCN GTNGARTTYTTYYTNTAY---TTYAGYGTNAAYYTNTGYGTNGGNCCNACNTAYGAYCAR GAYTGYGCNYTNCAYTTYAAYCCNMGNGTNGARGARAGYMGNGTNGTNMGNAAYCAYATG CARGGNGGNTCNTGGGGNCARGARGARACNAGYGGNGGNTGYCCNTTYAARAARGGNCAY CAYTTYCARYTNCARATHAARGCNCAYCAYCAYGGNTTYMGNATHAGYGTNAAYAAYMGN CAYTTYTGYGARTTYAAYAAYMGNYTNCCNMGNGARAGYATHCARTAYATHTAYATHGAR GGNGARGTNATHATHACNTAYATHCARTTYTCNGGNGGN------------CAYCCNTCN TTYCCN------------------------ACNCCNGGNTAYCCNCCNGCNCCNAGYTAY CCNCCNGCNCCNAGYTAYCCNCCNGCNCCNTCNTTYCCNTCNGCNCCNGGNTAYCCNGGN ATGGGN---GGNCCNATHTAYAAYCCNCCNGTNCCNTTYACNACNCCNATHCARGGNGGN GTNGTNCCNGGNAARATHGTNTTYATHTCNGGNATHCCNAAYCCNAAYCCNAGYMGNTTY ACNGTNAAYATGCARTGYGGNCCNTAYGAYTCNGGNGAYTTYGCNATGCAYTTYGAYGTN MGNTTYAAYTAYGGNGAYAGYCARAAYCARGTNGTNMGNACNCAYAARCARGGNGGNAAY TAYGGNAAYGARGARMGNCARYTNACNCAYTTYCCNTTYTAYCCNAAYACNCCNTTYCAR ATGATGATHYTNATHGARCCNGCNTCNTTYAARATHGCNGTNAAYAAYCARCAYTTYGTN GARTTYTAYCAYMGNATHCARCCNTTYAAYMGNGCNGAYCAYATHAAYGTNGTNGGNGAY GTNMGNYTNACNGARGTNMGNTTYCARTCNTCNATGTTYGTNCCNAAYTTYYTNGTNAGY TCNGGNACNGGNYTNACNCCNACNYTNACNCCNACNACNYTNGCNACNATHGARCARTCN TTYATGGARYTNCARCAYTCNGGNGCNMGNGAYCCNGTNACNCARAGYGGNTTYGTNCCN CCNGTNGTNGARCCNTCNAAYAGYAAYAGYGCNGAYCAYTCNCARGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATHTCNGAYYTNTCN AARCARGTNGARMGNYTNGAYTCNATGACNCARGAYGCNGAYMGNACNTCNTGGCARCAR GARTCNAAYACNGTNGARACNYTNAARGCNMGNCARMGNGARTTYCARTCNGTNATGGAY AAYACNGTNGTNGARCARGTNGAYAARAARYTNTGYMGNACNMGNCARAARAARGCNMGN YTNATGMGNMGNMGNTCNATHGARTTYCARCARMGNCARGARGTNGARGARYTNMGNGAR GCNAARGARAARGARATHAGYAAYTGGCARCARMGNYTNYTNYTNGARATGAARGARGAY YTNYTNAARAARGARMGNAARMGNGARATGGAYCARACNYTNAGYGCNGTNACNAARAAR ATHCARGAYGCNAAYMGNYTNGTNGAYACNATGACNGCNYTNGARAARYTNMGNYTNATH MGNCARGAYGCNGCNAARAARMGNGGNGAYAGYGAYATHGGNGARTCNMGNCARAGYTTY GARCARAARATHCARGAYATGACNMGNYTNGTNMGNTCNCARYTNGARGTNTAYAARGAR GARGARGARACNYTNMGNGGNGTNATHMGNTCNGARCAYGARGARACNAGYAARAARGAR AARGARYTNCARGARACNMGNAGYMGNGARGARCARMGNCARMGNGAYGARGAYYTNGGN AARATGYTNTTYGGN--------------------------------------------- ------------------------------------------------------------ ---------------AGYACNGTNGAYGAYGCNATHAAYGAYATHYTNGAYYTNGAYATH GAYGAYGAYGTNGAYGCNTCNACNAARAARGCNATHTCNAGYAAYAGYACNAARTCNACN ACNCCNCCNAGYGGNMGNAARGARGCNACNAARAARTGYTTYCCNGTNTTYTAYGGNGGN AGYAAYGAYGARACNGGNYTNGGNACNACNGTNAARCCNMGNGCNTGYGAYCARYTNMGN TGYACNGAYTGYGAYTTYMGNGTNTGYTCNTTYGAYGAYTTYTCNTGGAARAARGAYACN AAYTAYYTNTTYYTNMGNAAYAAYGTNCCNGAYTTYCARAARYTNAARTCNAAYYTNMGN MGNCARAARGGNTGYMGNGCNTAYTGYTGYCARTGYTGYTGGMGNGAYGTNTTYTCNYTN CARGARATHTCNGAYCCNAARYTNAARTGGGTNTGYGGNAARCAYGAYTCNCCNGCNAGY GTNATHGARGCNYTNATHTGYTTYTTYTCNATHTGGTCNGTNGTNGGNYTNGCNGGNTTY CAYTCNTAYYTNACNGCNTCNGARATHACNACNAAYGARGAYATHAARGGNACNTTYACN TCNAARMGNGGNCARGAYAAYTTYAAYCCNTTYAGYAARGGNTCNYTNTTYAGYAAYTGY ATGGGNATHYTNTGYGGNCCNGTNCCNCCNAGYYTNYTNGAYMGNMGNAARYTNATHGTN CCNGARYTNGARTCNTCNGTNCCNAAYAAYATHGTNGGNACNMGNACNGTNACNATHGTN TCNGAYCARGTNGTNCAYGARGAY------GTN---------AARAARCAYAAYATGATH AGYTAYCARGGNCCNGAYGGNTCNATHACNAAYAARGTNCCNAAYGGNAAYGGNACNGAR NNNATHAARTGYCAYMGNGTNAAYATHTAYCCNACNGCNCARGGNGARGTNAAYTAYTAY MGNGAYCCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GTNTGYCCNTAYAAYGCNACNCAYGARGTNMGNACNCCNGARYTNAAR TAYCAYATGGCNCARTGYCCNAAYMGNACNYTNYTNGARMGNGAYATGTCNTTYAAYGCN YTNCARAAYGCNYTNYTNGGNAARGARGARMGNGCNGTNAARGGNAAYACNGAYYTNCCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GARTCN GTNTTYYTNGCNGAYGTNACNCARGTNYTNAARYTNCARGARAGYTTYGCNMGNGAYGTN ACNCCNTCNGGNATGCCNGGNAGYAARATGAARAARGAYGAYATHATHTCNTGYACNAGY MGNTCNGARGAR------------------------------------MGNAGYACNGAY GARTGYAARMGNGAYYTNCCNGTNTGGATGTCNMGNAARYTNAARMGNAARTCNACNGAR TCNTCNYTNTCNGGNGTNGARAGYGAYGARTCN------TCNTTYAARTTYACNAARACN GTNTAYYTNATGAGYGARMGNGARYTN--------------------------------- ------------------------------------------------------------ ------ATHMGNACNGCNTCNGGNTCNAAYTCNCAYTAYGTNYTNYTNCCNGARGTNCCN CCNGAYACNGCNGARACNAAYACNGTNATGMGNATHGAYCARYTNCCNCARTTYTCNCAR ATHACNCCNAAYTCNTGYATHGCNGCNTGYGCNAARYTNTCNATHGARTAYGARACNAAR YTNGARAARCAYATHGAYACNYTNAARGAYCCNAARGTNGARAARACNTTYGAYAGYGTN TAYYTNCCNCAYGARGARATHGCNGTNCCNYTNAAYACNGCNTGGGCNACNGTNAARAAY YTNCAYTAYGTNGCNGCNAGYGAYGAYTTYMGNMGNGCNTTYTCNAARATHCAYCCNCAR GTNGARMGNGTNAARAAYGARMGNTGGGTNAGYCARCCNYTNTAYTAYTCNTTYAARGAR ATHGARGCNAAYAGYGCNAAYYTNTCNGARTAYCARAARMGNYTNGTNAAYYTNTAYYTN YTNGARGGNAARYTNAAYGGNGTNCAYYTNTCNACNGARGARAAYTCNAARYTNGTNGAY YTNMGNAARGARATHGTNAARGARAGYCARAAYTTYMGNAAYAARGTNMGNATHTGYACN GAYATHTTYACNCAYGAYGTNACNAAYTTYAAYCAYATHGAYGARATGCCNTGGCAYYTN YTNGCNCARATGTCNACNGAYAARACNAAYGCNACNMGNGGNCCNTGGMGNGCNACNYTN CARCCNGCNGTNTAYCARGCNATGATGACNTAYTGYAAYGAYMGNATGACNMGNTGGAAY YTNTGGAAYGCNTAYCAYGAYMGNGCNTCNCAYAAYCAYTCNGCNCARTTYYTNAAYAAY AAYYTNYTNATHGARACNYTNMGNTAYTAYMGNTCNGAYYTNGCNATHATGYTNGGNTAY GAYAAYTTYGCNGARATGTCNATGGARACNAARATGGCNGGNTCNGTNGARAAYGTNYTN AGYATGATHGARACNYTNMGNGCNMGNTTYGCNCCNGTNGTNTGGGARGARATGGCNCAR YTNCARGAYTTYGCNTCNTCNGARGGNTTYAARCAYTCNYTNGARATGTGGGAYYTNAAY TAYTGGAARMGNMGNCARMGNGARCAYYTNTAYAGYGTNAARACNGAYGCNGTNAARGAR TAYTTYCCNATHAAYTCNGTNYTNYTNGGNYTNTTYGAYYTNTGYACNAAYYTNTTYGGN GTNAAYTTYGARGARGTNACNCCNGARGTNGARGTNTGGCAYCCNGAYGTNMGNTTYTTY AAYGTNYTNGAYGGNGARACNGGNGARCAYATHAGYTCNTTYTAYTTYGAYCCNTTYGAY MGNCCNGGNAARATHTCNTCNGGNTAYATGGAYYTNGGNMGNGAYAAYAGYGARCAYTTY GGNACNTGGCCNTAYTCNTAYYTNTGYYTNMGNATHCCNMGNCCNCARTCNTCNTCNGAY CCNGCNYTNATGAGYTAYGGNGAYATHGARACNATGTTYTCNGARTTYGGNCAYGGNYTN CARCARATGYTNACNAARGTNCCNTAYAGYGARATHGCNGGNCARAARAAYATHGARTGG GAYGCNATHCAYGTNTGYGCNAARTTYATGAARATGTGGYTNTCNAAYCCNAGYGTNGTN AARAGYYTNAGYAGYCAYTAYAAYACNGGNGARACNATHCCNGAYGAYATGYTNTCNAAY ATGYTNAARTCNTCNCARCAYTGGAAYAAYTTYGARATGYTNTAYCARYTNTAYGTNTCN GCNTAYGAYYTNGARATHTAYATGACNAARACNCAYTGGCAYACNATHCAYAARCARYTN TGGGARAAYTTYATHCCNTTYCCNATHTGYGARGARGAYAGYYTNCCNTGYTCNATGATH CCNATHTTYTGYGARATHTAYCCNGCNGCNTAYTAYTCNCAYAARTGGTCNGARATGATH GCNGCNGAYATHTTYTCNGCNTTYCARGARGCNGGNYTNGARGAYCARGARAARATHAAR GTNYTNGGNMGNMGNTTYAARGAYACNTAYYTNTCNYTNGGNGGNGGNGTNCCNTCNTGY GARGTNTTYMGNCARTTYMGNGGNMGNGAYCCNTCNACNCARGCNYTNCARCCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGNAARGAYGCNAARCCNGARGAYGARACNGGNAARGCNGCNATHMGN MGNAARATHTGGGAYAAYYTNGARGAYAAYAAYYTNGTNTCNGTNCCNMGNCCNTGYCAY TAYMGNATHCCNAAYTTYGARGGNGCNGCNGCNGCNGCNGAYMGNYTNACNTCNYTNGAY GARTTYAARAARGCNCAYACNATHAARGTNAAYCCNGAYAARGCNCARGARCAYGCNMGN TTYYTNGTNYTNGARGCNGARAARGARYTNGTNYTNYTNAAYCARAAYCARAARGAYYTN ATGGTNCCNACNCCNGARYTNAARTCNGGNYTNYTNAAYMGNGTNGTNCCNGCNGARGGN TCNAAYAARGARGARYTNMGNCAYTGYTGYACNACNCARGGNGTNAARGARAAYAGYAAR GARATHGGNYTNGGNGAYAARGTNAARYTNGAYYTNATHGTNGTNGGNAGYGTNGCNGTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CCNCARTTYAAYGCNTAY GCNGTNGARAAYATGGTNGAYTTYCCNYTNMGNGARGAYGAYGTNYTNYTNGTNACNTAY CCNAARTGYGGNGTNCAYTGGTCNTGGGARATHYTNMGNATHYTNGTNACNGGNGAYATH GAYAAYAARGGNYTNGAYAARGARAGYTAYATGATGGARTGGGAYMGN---CCNGARAAR TAYAARGAYYTNCCNAGYCCNMGNATHYTNAAYAAYCAYATGCCNTTYCAYATGCARCCN TCNGAYYTNYTNAARAARAARCCNAARGTNGTNATHTTYTAYMGNAAYTTYAARGAYGTN GCNGTNTCNTTYTAYCAYCAYCAYTGYGCNATHAARGAYTAYGGNTAYGARAGYGGNGAY TTYGGNGGNTAYYTNCARMGNATGAAR--------------------------------- ------------------------------------------------------------ ------------------GAR--------------------------------------- ------------------------------------------------------------ ------------AAYCCNGTNACNGARATGMGNAARYTNTGYGAYTAYYTNGGNAARACN TTYGAYGAYAGYTTYYTNCARGAYGCNGCNAAYTCNACNAAYTTYGAYCAYATGAARGTN ACNAARGGNGCNATHAAY---------------CCNATHTTYTAYMGNAARGGNCARGTN GGNGAYTGGAARAAYCAYTTYACNGTNGCNCARAAYGARTGGTTYGAYGGNATHATHAAR AARGARATGGCNGGNATHACNTTYAAYTTYMGNTAY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARYTNTCNAGYCARTGGTAYAAYAGYYTNTCNATGGARCCNGAYGAYYTNAGY GTNCAYGTNGAYMGNAAYGAYMGNAGYGGNATHMGNAAYTAYATGCAYAARGARGGNYTN GTNATHGCNMGNGCNAARACNTTYYTNCARMGNCARMGNMGNACNYTNAARCARMGNCAR TCNGCNYTNGCNGCNGCNAARCARGARYTNAAYAARGAYAGYAGYGTNYTNCARCARTCN AAYCCNACNAAYGARGCNACNGARATGYTNGAYAARGTNMGNGAYACNYTNGARTCNGAR MGNGCNCARATHGAYGCNYTNCARTCNAARYTNGAYACNGAYTCNAARYTNYTNAARGAR AARGARGARAAYTAYAGYMGNYTNGARGGNYTNACNAARGARAAYGAYAGYGARGAYGAR TCNGARTAYAAYCCNTTYGGNMGNCCNTTYCAYGGNGTNCARATHCCNAAYATHGAYYTN AGYGARGAYGARAGYAGYGGNGTNAGYAGYTCNGARGCNAGYYTNGAYGGNTAYTTYCAY GCN---GGNMGNCAYAARCARTTYTCNAGYACNACNMGNACNAAYGAYGTNYTNGGNTCN GAYGAYYTNTCNMGNGCNYTNYTNMGNATHAAYCAYGAYYTNTCNCAYGTNYTNAGYGTN ATHGGNAARGAYGGNGARTCNGTNYTNGGNACNCCNYTNCCNMGNCCNCCNTCNACNCAR MGNTAYCARGGNYTNCCNGARGGNATHCARTGGACNCCNCAYCCNCCNAGYCARCCNCCN TCNAARGAYTAYTCNACNYTNGTNGCNACNGCNGARCAYTCNYTNGARMGNAARTGGMGN AARTAYTTYGGNGAYMGNMGNCCNCCNTTYACNGCNGTNCCNTCNCARYTNTCNTCNATH AARGGNTTYGGNTCNACNTCNAGYYTNTCNMGNGARAAYTTYCAYTCNMGNCCNGCNTAY TCNTCNATHCARTCNMGNYTNGAYGARCARAARGARTGGYTNMGNCARCAYCAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNTCNYTNYTNMGNTCNCCNAARGGN CCNGAYCCNACNGCNGAYATGGGNGTNCAYTCNTTYTCNTAYGCNYTNATGCCNCAYYTN GGNAAYATHCARGARTCNGGNGTNATHAAYGARGCNATHGCNTTYAAYACNCCNYTNAAR ACNGGNAAYGGNYTNAAR------------GGNAARGGNYTNGARYTNGCNCCNYTNTTY AARAGYAGYACNTCNCARGTNATHATHCARACNATHAARATGGCNGARGAYMGNAGYGGN AGYGTNATHYTNMGNYTNAAYGARGCNTTYGGNGGNAGYGTNAARGCNGAYATHYTNTCN GGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ACNMGNCAYGAYATHCCNAARGGNGARMGNTGYGCNGTNTGYCAYGGN AARYTNYTNMGNMGNMGNAARATHMGNCAYYTNCCNTGYGGNCAYATHTTYCAYGAYGAY TGYATHYTNCCNTGGYTNCARAARMGNACNGTNTGYCCNYTNTGYMGNMGNGAYTTYTCN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATHAARGAYYTNAAYTCNTTYATGAARGAYAAR GTNTAYTTYGTNGARTGYCAYNNNACNGTNGCNGAYGTNYTNYTNTAYCAYAGYYTNTTY CCNGTNTTYGARMGNATGTCNTTYCARGAYAARGARAARYTNATHCAYYTNTCNMGNTGG TTYAGYYTNATHCARAGYGAYGAYAARGCNMGNCARTCNYTNTCNCCNGTNACNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNYTNCARYTNGARTGYAGYAAYTCNGARYTNATGGAYYTNATGAARGGNGTNGTN ACNTGYCARACNGTNGARAARTAYTCNGTNTCNTCNYTNTCNAARGTNGCNCARAGYAAR TGYGGNATGGGNMGNAARGCNAAYYTNAARGARTCNATHTCNYTNGAYAARGCNGTNGAR TGYGTNAARAAYCAYYTNGARYTNAARCAYGTNAGYYTNGCNAARGTNGARGGNAAYGAY GAYAAYCCNATHAAYTCNGTNGCNGTNTGYGCNGGNTCNGGNTCNAGYGTNYTNAARAAY GTNAARGCNGAYYTNYTNGTNACNGGNGARATGTCNCAYCAYCARGTNYTNGAYGCNGTN CAYGGNGGNAGYAAYGTNATHYTNTGYCAYCAYAGYAAYACNGARMGNGGNTTYYTNMGN GAYYTNCARAARMGNYTNAGYAARGTNATGGARAARTCNGTNCARGTNTTYGTNTCNGAR AAYGAYMGNGAYCCNYTNGARATHGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TAYGCNGAYGAYYTNTGYYTNGCNACNCARTCNMGNAAYTTYAARGARATHGAR GAYAARYTNTCNGCNGCNYTNAAYACNYTNACNACNTAYTAYGARGARAAYTCNYTNAAY GCNAAYCCNAGYAARACNCARGTNTGYGCNTTYCAYYTNAAYAAYCAYCARGCNAAYMGN AARYTNATHGTNACNTGGAAYGGNGCNGCNYTNGARAAYAAYGAYTTYTCNGTNTAYYTN GGNGTNACNYTNGAYMGNACNYTNTCNTTYGCNCARCAYGCNAARAARATHAARGGNAAR GTNGCNACNMGNAAYAGYYTNTTYGGNAARYTNGCNAAYACNAARTGGGGNACNGAYCCN AARACNYTNMGNACNACNGCNYTNGCNYTNTGYTAYTCNACNGCNGARTAYTGYTCNCCN GTNTGG------GCNMGNTCNAGYCAYGCNAAYAARATHGAYCCNGARYTNAAYAAYGCN TGYMGNATHATHACNGGNACNYTNMGNCCNACN--------------------------- ------------------------------------------------------------ ------------------------------ATGGCNYTNTTYAAYACNMGNTCNCCNGAY GCNGAYGTNAARCCNGCNAGYGAYAARAARCCNCCNACNAAYYTNAARGARTTYYTNGAR GCNGARGGNYTNGAYGAYTGGCCNYTNCCNATGAGYYTNGARGGNCCNYTNGAYATHGAR TCNGARGGNYTNTTYATHGGNAAYCARGGNGAYATHGCNGAYATHYTNGAYGARGCNGCN CCNYTNGGNYTNCARATGYTNGARGCNATGGARGAYMGNYTNTCNACNYTNGARGAYAAR ATHAAYTTYTAYGCNGAYCARATHGTNACNGAYACNAARMGNCCNTCNMGNYTNGCNGAR MGNYTNTTYCAYTCNCCNACNAARACNTTYATGACNGAYATGTCNGAYTCNGAYGCNYTN AARTCNCAYMGNAGYTCNAARGGNCAYMGNAGYGTNGAYYTNYTNGAYACNATGATGGAR ACNMGNAARMGNAGYYTNGAYTAYTAYACNTTYCCNGGNTTYGTNCAYGGNGARTTYATH GARYTNCCNGCNCARYTNGARGCNCCNCCNATHYTNCAYMGNATHACNAAYGCNCARGAY TTYAAYTCNGGNTTYAARAARTTYTGGAARAARYTNTTYYTNTCNGARGCNTCNTCNGCN GTNYTNCARGAYGCNTTYTGGTGGATHTTYYTNGAYATGTTYAAYAARACNGARGGNTTY AARGAYGAYAARGAYTGYATHTTYGAYMGNATHGCNGAYAGYTAYGTNGCNYTNTTYACN AGYATHAAYACNGAYGTNAARGAYAARTTYYTNTCNGTNTAYCCNAGYTGYYTNTCNCAR GCNYTNTAYTAYACNTTYMGNGARGCNTTYCCNGARTCNAARTGGMGNTTYGAYGARACN TTYAARCARTAYYTNGTNAAYYTNGTNTAYGARTGGGTNACNGGNYTNMGNCCNGTNCCN GGNGTNTGGAARGGNTGGAAYGARGAYGGNYTNGAYGGNAAYCARACNAGYMGNGARAAY GARACNGCNAARAARATGYTNGARGCNGCNGCNYTNAAYAARAARGTNGARYTNAGYYTN GAYATGGAYTCNTTYGCNAARGTNATHGAYAARYTNGGNACNGARCCNGAYAGYACNCCN CARGGNCAYATGTCNMGNGARATHACNAARACNAGYAAYAARGTNTCNGTN------YTN TCNMGNGGNAARTCNCAYYTNYTNAARCARGARTCNCAYCARATHGGNCCNGGNCCNGAY TAYGARMGNGTNAARTTYAAYACNTCNGGNMGNAGYCCNYTNATHGCNCAYTAYYTNCAY ATGMGNCARYTNMGNAGYTAYAARCARCCNGGNATGAARGTNMGNMGNACNGARATHYTN AARYTNCCNCCNGAYGGNCCNACNTAYCARCARTTYATHGCNAAYACNYTNAAYAARGCN GARTCNYTNGARAARGARTAYACNMGNATHTGYGAYCARACNTCNACNGCNATHYTNGAR YTNGARMGNTAYAARMGNGAYTCNAAYMGNGARATHGGNGARYTNAARAARGCNYTNACN AAYATHAARACNATHCCNGARMGNMGNTCNYTNATGGARAARATHTCNGARTAYAARGAY YTNATGATHAARGARAARCCNYTNYTNGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------AAYGGNAGYGCNGARTTYYTNCARAAYMGNGTNAAR GGNMGNGCNAARAARAAYTTYYTNGCNGARGARGARGAYYTNGAYMGNGTNMGNGTNMGN GCNGGNGARCAYAAYACNMGNTCNTCNMGNAAYYTNTAYAAYYTNTGYCARAARGTNAAR CARYTNCARMGNGARGTNAGYCARTCNGAYYTNAGYAARCCNACNAARAARAGYCARATH TCNGCNCARYTNAAYGCNACNTAYMGNGGNGCNGTNMGNGCNYTNCARGTNTTYGTNAAY CARYTNCCNTAYCARGAYYTNCARATGGGNYTNCCNTCNACNTAYAAYGARYTNGCNYTN YTNYTNMGNCARYTNACNACNYTNATGACNYTNACNCARCARGGNTCNAARGTNGARTCN GAYAAYAAYGTNYTNACNYTNYTNGAYCARGTNGAYGAYTAYAAYTCNAARTGGTGYTCN GGNCARCCNYTNCAYAARAGYACNGCNACNGCNAAYCARAAYGTN------ATHCARAAR GARTGGATHAGYGAYACNAARGTNGAYGCNGAYYTNYTNTCNAARAAYGTNACNGARTTY CCNGTNAGYGGNGCNACNACNGCNTCNCARAARAARAAYGTNYTNAGYMGNCARAARCCN ACNYTNMGNGCNAGYGGNAARGARAAYMGNATHATHYTNGARAAYGARAARTCNTCNATG AAYAAR---------GCNTCNYTNGGNGGNCARAARACNTTYGGNTTYGTNTCNYTNGAR TCNAARCCNGGNCARTCNAGY---------------------GAYACNACNAARGGNTAY ATGYTNCCNCCNGARYTNATGGCNAARMGNGARMGNGCNCARMGNGCNGTNGARYTNTCN MGNAARAAYTTYGCNGARTCNACNCARTCNTCNMGNTGYAAR---GCNGCNAAYATGCAR MGNCCNCAYTCNGCNCCNTCNCCNGGNMGNAARAARGARGTNAAYTTYGAYYTNMGNGAR GAYAARMGNTCNCAYCARCCNTGGATHCCNGCNGGNTGYGCNCCNTGYAARCARCAR--- MGNCCNMGNTCNTCNAGYGCNGARMGNATHCCNTTYTAYGTNAARACNATGGAYGGNCAR GARGTNTGGGAYGTNATGCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GAYATHATHGAYAGYCARYTNTTYGAYTCNCCNCAYCAYCARAGYYTNCARTCNGTN GTNCCNACNYTNGTNTTYAAYGCNGTNMGNYTNTGYGAYTCNACNATHACNTTYAAYAAR ACNYTNTCNCAYYTNGCNTCNMGNYTNAARYTNAAYATHGTNGARACNYTNAAYATHGTN GGNGARGAYGGNTAYTCNGTNYTNCAYYTNTGYGTNATHAAYGGNCARTTYGARGCNGCN AARYTNATHYTNGARYTNGGNGCNGAYTGYAAYMGNAARTCNGAYATHGGNAAYTCNGCN ATHTCNYTNGCNATHGCNTAYMGNCAYTAYAGYYTNGTNCCNYTNYTNYTNTCNTAYTCN GAYGTNAAYACNCARGAYTCNGAYCAYGAYACNCCNYTNATGTTYGCNGCNTGGAAYAAR GCNCCNAARATHGTNTCNGCNYTNATHCARCARGGNGCNAAYATHGAYGGNAARAAYAAR TAYGGNAGYACNCCNATHTGGAAYGCNGTNTAYAARTCNTCNGCNGARTGYGTNYTNATH YTNYTNAGYCAYAAYTCNYTNATGGAYGTNCCNTGYGAYGGNACNGAYYTNTTYTTYAAY ---GARAGYGAYTGYCAYGAYAAR------ATHACNAARYTNTAYCCNGGNCAYAARMGN TCNYTNYTNTGGGTNGCNGTNGAYMGNYTNGGNATHAGYGARGARAGYYTNAARGTNYTN YTNATHYTNYTNGARGCNGGNTAYGAYGTNACNAARGARCAYTGGYTNMGNMGN---GGN AAYCARCARTCNGTNGAYTGYCCNAAYATHYTNCARGARAAYCCNGCNYTNYTNGAYATG YTNYTNTTYYTNTAYATGMGNCCNYTNAAYYTNAARGAYYTNTGYMGNAAYACNYTNMGN AARTAYCAYMGNCARAGYTAYYTNTCNTTYCAYGARTGGYTNMGNMGNYTNCAYYTNCCN TCNACNATHACNAGYTTYYTNAARYTNTCNTAYATG------------------------ ------------------------------------------------------------ ---ACNYTNGGNCARACNYTNTAYACNACNGGNTAYTAYCCNCAYACNYTNYTNYTNTGG ATHGCNTGYAGYYTNCCNYTNTCNGTNTGGATGTGGGGNTCNAAYAARTTYAAYAGYTCN YTNMGNCARCARGCNYTNAARMGN------------------------------------ ------------------------------------------------------------ ---------------------GARMGNGARMGNGCNGAYMGNGARMGNMGNACNMGNATH GCNGARGGNTGYACNGGNAARGTNATGGAYATHTTYTTYGTNYTNGAYTCNTCNTCNTCN ATHTAYATHAAYGAYTAYATGTCNCARCAYMGNYTNGTNMGNGAYATHATHAGYMGNTTY GAYGTNAGYAAYGARGCNACNMGNGTNGGNATGYTNACNTTYAGYGAYGAYYTNCARTAY CCNGTNATHAAYYTNGAYCARTAYAAYGGNAARTCNGARYTNYTNAAYAGYATHACNACN AGYAAYYTNCCNTAYMGNACNGGNGTNACNAAYACNGAYATGGCNATHMGNTTYGTNMGN ACNCARCCNACNTTYMGNMGNGAYATHACNAARGTNATGATHGTNATGACNGAYGGNGGN TCNMGNTCNCCNGGNTCNACNGCNMGNGARGCNGARYTNGCNMGNGAYAGYGGNTTYTAY ATGTTYGTNGTNGGNATHGGNCARTAYATHGARGARMGNGARTGGMGNGCNATHGCNACN AAYCCNGAYGARAGYTTYGTNTTYAAYATHACNAAYGCNMGNTTYYTNGARGAYGTNCAR TTYTCNYTNCCNCCNMGNGCNTGYGCNYTNCCNCCNYTNYTNACNGCNTCN---TGYAGY ATHAAYMGNATGTCNGARGTNTAYTTYGTNGCNAGYMGNTCNGCNGARAAYGAYGCNCAR GCNTTYATHGARGARTTYGGNMGNMGNACNAARGAYCARTCNGAYYTNYTNMGNGCNAAY TAYTAYATHGAYMGNTGYGCNAAYGTNGARGAYATGCARYTNYTNAAYAAYGARCCNTTY ATHTGYAAYMGNTAYGAYCARATHGGNAAYCCNATHCCNACNGCNGGNACNGGNGARATG TTYTCNMGNGCNYTNMGNGCNATHMGNGARAAYACNGAYMGNGAYACNAAYCAYGTNGTN GTNYTNTTYGCNGAYGAYGAYACNATGACNGTNGAYMGNTTYGAYYTNGCNAAYAARGCN MGNACNGCNCARAAYTTYGARGGNGCNACNGTNGTNGTNGCNGAYYTNGGNATHMGNACN TAYMGNGAYTTYGCNCARMGNATGGCNGGNGGNMGNAAYAAYTTYATHAGYTTYGCNGCN GGNMGNGAYYTNGCNAGYCARACN------------------------------------ ATGGCNGAYAGYACNAAYCAYCCNGAYYTNYTNTTYGAYAGYCARCCNGARAGYTCNGGN TTYGCNAAYGAYGAYTTYGARAARGTNGAYGCNYTNGGNAGYCAYGAYGAYGTNTCNGCN GCNGCNTCNGGNGCNGARTAY------------GAYGTNGAYCARCAYGCNGARATHTCN ACNACNATHGAYGARGAYGTNGCNGTNGARGARGARGCNGARGCNGAYMGNTTY------ ------GCNGGNTCNCAYGAYGARCCNGCNTAYTCNTCNGARCCNYTNATHTCNTGGGGN AAYGAR---------------GARAAYGARGTNACNGCNGAR------------------ ---GTNCARCCNTCNGCNCCNGTN------CCNGARAAYAAYGARCCNYTNGTNAAYTTY ---GAYGAYAGY---TCNTCNGGNCAYAAYTAYATGCARTCNTTYATGCCNTCNGTNCCN TCNACNAGYCARACNTCNGARCCNAAYYTNGTNGARCCNAARMGNGARGARAARAGYTTY AARGARAAYAARCARGAY---------------------------------------GCN GTNCAYACNGTNCARAGYGGNACNGTNGARTCNTCNAARGGNTCNTGGYTNAARGGNGTN GAYCCNMGN---------------------------------GTNATHGAYYTNATHTAY TGGMGNGAYGTNAARACNACNGGNATGGTNTTYGGNGCNATGYTNGTNGTNYTNYTNTCN YTNGCNATHTTYTCNYTNYTNAGYGTNGTNGCNTAYYTNTCNYTNGCNGTNYTNGTNGTN ACNTTYAGYTTYACNGTNTAYAARAARATHATGGGNGCNGTNCARAARTCNAAYGARGGN CAYCCNTTYAARCARYTNATHGAYTCNGAYATHACNYTNAAYGARGAYAARYTNAARAGY GTNATHCARAGYGTNYTNAARAAYGTNAAYTGYACNATHAGYGARYTNMGNMGNYTNTTY YTNATHGARGAYATGGTNGAYTCNATHAARTTYGGNYTNYTNYTNTGGGTNYTNACNTAY GTNGGNGCNTGGTTYAAYGGNATGACNYTNATHATHYTNGTNGTNATHAGYATHTTYACN YTNCCNAARGTNTAYGARACNTAYAARGTNCARATHGAYAAYTAYATHGCNYTNGCNAAR TCNCAYGTNGAYAAYGTNATGACNATHGCNCARAGYAARYTNCCNTTYYTNAARAARAAR GARAARGCNCARGGNATHAARAARTTYTCNTGGYTNAAYAARTTYGGNCCNGARTTYMGN ATHMGNGGNGARCARGTNCARATHATHTCNGARCCNCARCARTTYTAYGARATHYTNAAR GTNAARACNMGNAAYGCNAARAARMGNYTNACNYTNGCNTCNYTNTAYYTNGGNACNGGN CARYTNGARYTNGAYYTNGTNTCNAAYATHGAYGARGCNTGYMGNGCNGCNCARTCNCAR GGNTCNTCNGAYYTNGARGTNAAYATHYTNYTNGAYCAYACNMGNGGNTCNMGNGGNMGN GTNAAYTCNMGNACNATGYTNMGNCCNYTNYTNGARAARTGGCCNAARGTNAARGTNGCN YTNTAYCAYACNCCNGAYYTNMGNGGNTGGYTNAARAAYGTNTGYCCNGARMGNTTYAAY GARTTYATHGGNYTNAAYCAYATGAARATHTAYYTNATHGAYGAYAGYTTYATHATHAGY GGNGCNAAYYTNAGYAGYGAYTAYTTYACNAAYMGNCARGAYMGNAAYATHYTNTTYAAY GAYTGYCCNCARYTNGCNAAYTTYTTYAAYGAYYTNGTNAARTCNACNATGTCNTTYTCN YTNCARYTNCAYGGNGAYGAYACNYTNCAYYTNTCNCCNGAYTGGAARATHCAYCCNTTY YTNGAYTCNGAYAARGGNCARAAYTTYAARTCNGCNGCNAARACNAARGTNCARCARTGY YTNATHACNCAYTCNTCNGTNCARGAYGARGCNACNMGNAAYAGYMGNATHTTYAAYGAY GCNTCN---------------------------------ACNGAYACNGTNGTNTAYCCN YTNATHCARATGGGNCCNYTNGGNGTNAARAAYGAYGARATGGCNACNGTNGARYTNTTY YTNMGNTCNGAYTCNACNGAYCARATHYTNYTNTCNTCNGGNTAYTTYAAYYTNACNGAY CARTAYACNGAYGTNATHATHGAYAAYGTNGAYTCNAARTTYAAYATHYTNATHTCNTCN CCNAARGCNAGYGGNTTYTCNGGNGCNAARGGNYTNGCNGGNACNGTNCCNTAYTCNTAY ATHTAYYTNGCNMGNCARTTYTAYAARAARGTNTGYAARGCNGGNCARAAYCAYMGNATH AAYATGYTNGARTAYGARMGNGAYGGNTGGACNTTYCAYAGYAARGGNYTNTGGTAYTAY GTNMGNAAYGAYCCNYTNCCNMGNYTNACNGTNATHGGNTCNCCNAAYTAYGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CCNAGYCAYGCNYTNGGNGCNAAYGTNCARAARGTNYTNGCNATGATGAARTCN CAYAAYACNGCNYTNTGYTCNCARATHCAYCCNCAYAGYAAYCAYGAYGGNCARMGNTCN CCNAGYCCNTCNTCNTCNMGNTCNGGNTCNAGYGCNACNTCNTCNGTNGAYCARGAYYTN ACNGAYYTNYTNAAYCARYTNCARGARGARTTYMGNCARYTNAGYAGYGAYCAYCARGAR YTNGTNCARCARYTNAAYGGNGCNATGGAYAARGGNGARMGNYTNGAYYTNGARCARGAR ATHGARGTNATGGTNTCNMGNATGGARGCNAARGCNCARCARATHACNAARATHMGNCAR CAY---MGNGGNTAYCCNGGNCARMGNCCNGARAGYMGNGARACNTAYCCNGGNGAYGAY ATHMGNMGNTCNGARATHCCNTCNTCNCARGCNGAYCARGTNTCNTCNGGNGARAGYGTN ATHCARMGNCCNYTNACNGAYTCNAAYTAYGTNMGNAARAAYYTNACNGARAGYGGNCAY GCNATGYTNYTNTCNGCNTTYCARMGNGAYAAYGCNMGNAGYTCNCCNCARACNATHTCN ACNGCNCARTCNTCNCARGTNAGYGGNGCNTCNGTNACNGCNGAYMGNYTNATHAAYGCN ATHATHATHCAYTCNATHAAYCARACNTCNCCNGARGARAARAAYAAYGCNTCNCCNTCN CCNYTNMGNYTNGCNGGNACNCCNACNTCNGAYCARGCNTCNAGYTCNAGYAGYGARCAR MGNCAYYTNGCNGARTCNAARMGNTAY---ATGATHGCNGARGGNGGNMGNCCNGAYYTN ATGGAYCCNATGCARMGNGARATGYTNGAYCARMGNAARMGNCARGCNGCNGCNGARCAR MGNCARYTNCARGARATGCAYGGNMGNMGNCARCARGARCAYCARCAYMGNCARMGNCAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TGGMGN TCNCARACNYTNMGNAARGGNMGNCARATHYTNGCNYTNACNCARMGNCAYYTNGCNGCN GARGCNGGNGGNGGNACN------TCNCCNYTNCCNACNCCNCARCCNAARTCNMGNAGY TTYGGNTTYATHAARTTYYTNGGNYTNGGNYTNCCNYTNGCNACNGGNGGNATHGTNGGN TAYGCNTGGTAYGAYAARGAYTTYMGNAARCARYTNGARGAYAAYGTNCCNTAYGCNAAR GARYTNYTNGARAAYGTNYTNCCNCCNAAYGAYATHAAYAARCCNCCNAARAGYGTNGAR AARTCNCARACNYTNACNCCNATHTTYGARGCNAARGGNYTNCCNAARCARGAR------ ---------------------------YTNTCNAARGTNGARCCNGCNAARCCNACNGGN GCNGCNGAYTCNAAYAARAARGAYACNAARAGYGARCCNYTNTCNYTNGARCARCARYTN MGNAAYAARGARATGGARGAYAARGCNGAYAAYGCNGCNYTNGARGTNGTNGTNGARAAR YTNYTNGARTCNGGNCARAAYTGGGTNTCNGARGCNTCNMGNGCNCARYTNGAYGTNGCN AARGCNACNAARAAYCAYAGYTCNYTNYTNAARAARGCNATGGAYGARACNTCNAAYATH YTNGAYAARGAYGCNGARTGGGARGCNGTNACNGTNGCNTAYAARGARMGNGCNAAYGCN GTNACNMGNGCNAAYGARYTNGTNGAYGARGCNMGNMGNAGYATHGARAARYTNAARAAR GTNYTNGAYGARGCNAARGCNAAYAARGTNACNATGAARAAYCCNGCNATHTAYCCNGCN ACNAARAARYTNGCNGAYTTYACNAARGARATGTCNAAYGCNGGNGCNAARGTNMGNCAR GCNGAYGCNGAYGCNAARGTNATGYTNAARTAYAARGAYYTNGTNGAYAARGGNMGNAAR CARTTYCARATGGARYTNGARAGYYTNGCNCCNGAYGTNAARGTNGGNGGNAARGGNCAY AARYTNTCNGAYGARGARYTNAAYGCNYTNATHGCNCAYGCNCAYMGNMGNATHGARCAR YTNCARAARCARATHGCNGARCAYYTNGCNATGGARMGNAARMGNYTNAAYYTNGCNYTN GARGCNCARMGNGARGARAGYAARGGNATHACNCARGCNGCNGTNAGYGAYGARMGNGCN MGNYTNGTNACNGARTTYGARYTNGARAARCARAARATGGARATHGARTTYGCNGCNTGG ATGGARGCNGAYGTNMGNAARCARYTNAGYMGNCARGCNGCNGCNCAYAGYGAYCAYYTN AARGAYGTNYTNTCNGTNCARGARCARGARYTNAAYAARGAYTTYGAYMGNAARGTNAAY ATHAARYTNYTNGARGARMGNGARAARTTYCARGCNGARACNTCNGGNTGGATHTCNMGN YTNAARGGNATHGARGCNGCNATHGAYGCNMGNGCNGCNAAYGARAARYTNGCNCAYACN GCNCARGAYYTNTGGYTNGCNTGYATHGCNYTNAAYTCNACNATHCARTTYGGNGAYGAR GAR---GCNGAYYTNCCNATHCCNYTNCARAARCARYTNGAYACNGTNATHACNTCNTCN AAYAARCAYCCNTTYGTNCARACNGTNGCNAAYACNATHCCNGARGTNGCNYTNGARMGN GGNATHTAYACNGARAAYAAYYTNMGNGAYMGNTTYGTNAARGTNTCNCARATHAGYMGN MGNYTNGGNYTNATHGAYGARTCNAAYGCNTCNYTNTAYAARTAYYTNGTNTCNTTYYTN CAYTCNTTYTTYACNGTNAGYAAYGTNGCNGCNTAYTCNGARAARGAYYTNGTNTCNYTN GAYGARATGGAYAAYTTYAARYTNGTNGCNAAYGCNCARTAYTGGATGGARAARGGNAAY YTNGAYYTNGCNGTNMGNTTYATGAAYCARYTNACNGGNGARTCNMGNMGNGCNGCNAGY GAYTGGATHACNGARGCNMGNYTNYTNYTNGARACNMGNCARGCNGCNCARACNATHYTN ACNTTYGCNTCNGCNACNGGNYTNGCNGCNACNTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNTCNTCNTAYGCNGGNAGYCCNGCNGAYTCNACNATGGGNTAYCAYAAY ACNAAYTCNAAYGAYACNGARCAYGAYCCNCAYGGNACNAARACNYTNGCNCAYCARGTN GCNCAYAAYCAYACNTAYAAYACNYTNCCNGGNCAYGTNCCNMGNGARGTNAARAARTAY GCNCCNAARCCNCARTCNAARAARGGNCCNCARTGYMGNGAYGARAARAARGCNATGGAR ATGAARGTNCCNTTYAGYATHGAYGARATHGTNGARTCNCCNGTNGARACNTTYAAYGAY YTNYTNACNAARTAYACNYTNACNGARGARCARYTNACNYTNATHMGNGAYATHMGNMGN MGNGGNAARAAYAARYTNGCNGCNCARAAYTGYMGNAARMGNAARGTNGGNGTNATHGTN ACNYTNTCNGAYGARATGACNGAYYTNCARAARGCNMGNGAYMGNYTNATGGARGARMGN GARGARATGGARMGNGARACNMGNMGNATGMGNGARAARTTYGGNCAYYTNTAYACNCAY ATHTTYGARTCNYTNMGNGAYGARCAYGGNCARCCNTAYGAYCCNAAYCARTAYTCNYTN CARCARTCNAGYGAYGGNAAYGTNTTYYTNGTNCCNMGNAAYGTNACNACNAAY------ ---ACNACNACNGAYGTNAAYGGNAAYAGYAGYAGYGGNMGNGGNAGYMGNGAYMGNAAY GAYMGNATHAARAARMGNMGNMGNGGNATHTAYTCNGCNATHYTNGCNGTNATHGCNYTN GTNTTYGCNATHYTNACNYTNYTNAAYYTNGCNTTYATHYTNGTNAARMGNGGNCCNAAR AARATGTTYTAYAARAARAARMGNGAYGARGARCCNGCNTGYYTNMGNGAYTCNGTNTAY GGNGARCAYGGNTAYYTNCAYYTNGARGARGTNMGNATHCAYTAYGTNGCNAGYGGNCCN GCNGARAARCCNYTNYTNYTNYTNYTNCAYGGNTTYCCNGARTCNTGGTAYTCNTGGMGN CAYCARATHAARGARTTYTCNAARGAYTAYMGNGTNGTNGCNATHGAYATGMGNGGNTAY GGNGAYTCNAGYAARCCNTCNGGNATHMGNMGNTAYAARYTNGARTGYYTNGTNAARGAY GTNAARCARATHATHACNGCNYTNGGNTAYAGYTCNTGYATHYTNGTNGGNCAYGAYTGG GGNGGNGCNATHTCNTGGGCNTTYGCNGGNTGYTAYCCNGARATGGTNGAYAARGTNATH ATHATGAAYAGYCCNCAYGCNMGNGTNTTYAARAARTAYYTNCARAGYCAYYTNGCNCAR TTYAARAARAGYTGGTAYATGTTYTTYTTYYTNGTNCCNTTYYTNCCNGARATHTAYYTN TCNYTNAAYGAYTAYAARCCNTTYGARGTNATGTTYAARGGNAARAARAAYGGNGTNMGN ACNGAYGCNACNACNACNGARGAYGTNGARGTNTAYAARTAYYTNTAYCCNAAYMGNCAY GCNTTYACNGGNCCNATHAAYTAYATHMGNGCNGGNYTNTTYTAYCCNTCNTCNTCNTGG YTNTCNCARAARGTNACNAARCCNGTNYTNYTNATHTGGGGNTGYMGNGAYYTNGCNYTN GARACNGGNYTNGCNGAYTGYTGYAARGARTAYGCNTAYGAYYTNAARATHGARTAYATH AARGAYTCNAGYCAYTGGGTNCARATGGAYCAYGTNGARAARGTNAAYTCNYTNATGAAR GARTTYATHACN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGYTNAAYAARYTNACNACNGTN GCNMGNTTYATHCCNMGNGTNMGNAAYGCNMGNAGYATG---GGN------GGNGTNCCN GCNAAYTTYAARCCNATHMGNCARGTNTGYGARGARAAYAARAGYCAYATGAAYTTYATG CCNGTNCCNCARGGNTCNTGGCARGARGCNTAYAAYGCNMGNAAYTCNAARYTNAAYATG ATHYTNYTNGGNAGYYTNGCNGCNACNYTNGCNACNTTYGGNATHYTNTAYCARACNGGN TGYATHTAYYTNCAYGGNCCNCCNCCN---------YTNAARGAYAARAGYTCNAARYTN AARGTNCCNCAYMGNTTYCAYAARYTNGTNGCNGARAAYCAYACNYTNYTNGARAARTGY TCNACNGCNAARATHGTNAARAARATGCCNAAYACNGAYGCNGCNYTNCAYTTYGTNGAR MGNYTNAAYGARACNAAY---GARGTNAGYCARGARYTNTGGGCNAARGCNAARGCNYTN ACNTGYYTNCARAGYCAYCARYTNATGYTNAARTCNYTNAGYTCNYTNGGNATHGARGCN ATGTCNGARACNACNTCNTTYGARACNGTNTAYMGNGCNAARAARYTNYTNGARTTYATH YTNTCNAARTTYGCNCARACNCARGAYGARGCNGAYTTYTTYTCNAARGTNCARTTYMGN CCNTCNCCN---------------------TCNAGYMGNATHACNGCNGCNACNCCNYTN TCNAGYGAYGARACNGTNATHGGNACNYTNTTYAARAAYCARGARTTYCARYTNGCNGGN GAYGCNYTNACNAGYTCNAARGCNTGGACNCAYYTNCARTTYGARAARAAYATHMGNCAR YTNCARYTNCAYYTNATHTGYYTNTCNGARACNGARTGGTGGGAYATHGTNTGYCARGAY CCNGARAAYGGNGGNATHGTNCARATHATHCAYAGYYTNYTNACNTCNAGYGGNGARTTY YTNCCNACNATHGTNCARAAYCCNTAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GTNTGYAAYGARGTNYTNAAR TCNATGCARGGNTGGGARTAYGTNTCNTGYGTNATHGARATHTAYMGNGTNGCNTGYMGN GTNATGACNGCNATGMGNTCNACNGCNATHTCNAGYTCNGARYTNGARCARACNYTNAAR GARATHGAYYTNYTNTGGAAYAAYYTNTCNGCNTTYYTNGTNGGNGCNTCNYTNYTNCCN GARCCNTCNTCNYTNGTNTTYACNAGYGCNATHYTNAARTCNGAYCARGAYTCNTCNACN TCNTCNGCNTGYGGNGTNTGYYTNYTNAAYGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNGAYCCNTAYTCNGAYGAYAGYAARGCNCCN TTYTAYMGNCARCCNGCNGGNATHMGNAARAARAARAARAAYGARGARAARGARGARGCN GGNGCNATHAAYGCNACNGCNCAYAAYATHGARGTNAARATGMGNCCNGAYACNCCNCCN YTNACNGTNMGNGAYTAYYTNCCNGCNGGNGTNGGNGAYAARGTNTAYTCNACNGAYAAY MGNTTYCARCARGARTGGYTNACNGGNAGYTCNCARATHTTYCAYCAYGAYGAYGGNYTN ATHAARATGGAYTCNAGYAAYAARTAYMGNAARAAYYTNCARMGNGARATGCCNCARCAR CCNGARYTNTGGTAY------GARTCNGAYGARMGNCAYGARACNAARAAYGCNAARATG TCNTTYAARCCNCAYAARGGNCAYAARMGNTGGATHGGNYTNCCNGAYACNGTNGARGAR CAYTAYGGNATGATGAARGAYGTNACNGCNGGNTTYGAYCCNGTNTTYTTYAARGARCCN GAYCCNAARCARAARMGNAARATHAARCARAAYAARATHYTNGGNTCNATHGTNCAYGAY TGGMGNAAYAARTGGTTYYTNAAYGGNCARTTYGCNGAYGCNACNCCNGAYGAYYTNATH MGNGAYATGGCNGAYATHCARCCNCAYGTNMGNYTNAARGCNGTNGGNACNGTNGCNAAR GCNGCNGARTAYAARCCNCCNACNGAYTCNAGYATHGCNYTNGAYAGYTCNGTNTAYGAY CCNATHAAYGAYYTNCCNGARCARATHTTYGTNGCNYTNGARTGYYTNYTNGAYGAYAAY AAYGAYCARGTNMGNAARGCNGCNGCNATHACNYTNTAYTCNYTNGAYMGNCCNTCNGAY AARGCNAARGTNMGNYTNMGNGARATGYTNAAYGCNGARAAYGCNGTNGAYMGNTGGGCN GGNGCNCARTGYYTNGCNCAYTAYGGNGARTGYGAYTCNGAYGTNGTNGCNGARATHATH AARCARATHYTNGAYTCNGARTCNGCNATHAARCAYGARCARGGNATGGCNYTNYTNGCN AARATHAGYAAYAGYAGYACNYTNGTNCAYTGYATGGTNGCNGARCARYTNAAYAGYAGY AGYTGGMGNTAYMGNGTNATHGCNTGYAARATHYTNCCNACNYTNTTYGGNTCNATHAAY MGNGAYATHACNCARAARYTNTCNGARYTNATGTGGCAYGAYTGGCAYGTNGARGTNMGN AARGCNGCNGCNCARTGYYTNGGNAARACNAGYCAYGGNMGNGAYGTNCAYGAYGAYATH MGNGAYMGNATHYTNAAYGGNACNGARMGNACNAARATGGARGCNATHAAYAARYTNGGN CARYTNGGNATHATGACNGCNAARYTNYTNCCNGCNTTYYTNAAYTGYTTYAGYGAYTCN TAYGTNTCNATHMGNTGYGARGTNTGYATHACNTGYGGNAAYYTNCARATHAARGARGAR CARGTNYTNGARMGNYTNGTNCAYYTNGCNACNTTYGAYCCNATHTGGAARGTNAARGCN YTNGCNATHCARGCNYTNGGNAARATHGGNGARGTNAAYGARGAYATHAARGARTGYYTN YTNTGGGCNATGMGNTAYGARGARAARCCNGGNGTNMGNGCNGARGCNTGYCAYTCNYTN ATHGCNYTNGAYATHGAYGAYGARGAYGTNATHGARATHYTNCARGARMGNYTNYTNGTN GARTCNAAYCARYTNGTNMGNGARGARATGATHGARGCNYTNTCNYTNTTYGGNTAYAGY ACNTCNGARGAYATGGAYACNGTNGCNCARATHAARGCNGARGTNMGNAARYTNTGYACN MGNAAYATHATHGCNTCNCARATHATHGTNAAYGARAAYGAYGAYATHAARMGNGARCAR YTNAARMGNATGGTNTGYCARACNGARAARGAYATHGARACNYTNAAYGARMGNAARCAR ATHATHYTNCARMGNATHMGNTCNCARGCNMGNAGYAGYMGNGCNAGYAAYAARGAYAGY YTNACNTCNTCNCCNCCNCCNMGNACNTCNACNCCNYTNYTNCCNACNGTN------AAR CARAGYAGYACNACNACNCCNGARCCNGTNAGYMGNGARGGNACNGTNTTYACNCCNACN GCNGAYAARGARYTNGARGCNATHYTNAAYCARGAYGARGAYYTNGARAGYGTNACNGAR TCNACNAGYGGNAARTCNMGNCCNGTNACNGAYGGNTCN--------------------- ---ATGGCNGARACNCCNGGN---GARAAY---------GTNAARGTNTCN--------- AARATHGAYYTNGAYGCNGARGAYGGNCARATHACNGTNACNGARGCNGARMGNYTNGAY ACNGCNAARAGYAGYGCNAARCARATGCARYTNAGYYTNCCNMGNAGYCARGGNGGNYTN YTNTCNCCNATGGGNTCNATHGCNGAYYTNAARGGNTCNMGNYTNACNATGAGYCAYATH TCNGGNAARMGNTCNATHATHAGYMGNGAYAGYYTNMGNGARMGNGARAARYTNAAYGCN GARGTNAAYACNATHTAYGCNGAYYTNAAYGCNMGNTAYGCNGAYATGATHCARCAYYTN GTNAARATHGAYAARGGNYTNAAYACNAARGGNTCNTCNGCNGARTCNAGYACNGTNGAR AGYYTNAAYGTNTCNAAYGTNGGNTCNAGYCAYATHGCNMGNYTNAGYCAYCARGARATH ATHGAYGARAAYATHCARTCNGCNMGNCARGARAARGGNGCNGGNGAYYTNTAYAARAAY TGYAAYGAYCARAAYAAYAAYGARCAYYTNCARGARTCNAARGTNGARACNGAYGGNGGN GTNTCNGAYGARACNGCNAARTAYGARGAYATHGAYGGNGAYGARGAYGGNTTYGCNGAY GCNGARTGGAARTCNTTYGTNGARACNYTNTCNCAYGARGAYGAYAAYGAYGAYGAYACN ACNTAYCCNTAYGCNGARGAYAAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARACNATGGCNACNAAYCARYTNTCNGARTCN ATGYTNATGGAYATHACNYTNCARAGYMGNGAYGGNMGNCAYGCNCARGARGGNAARMGN GAYGTNCCNCCNYTNGCNATHTCNATGGAYACNGAYCAYTTYAARTGGYTNCARGARCAR GCNTCNAARGCNCARGTNMGNGCNMGNCAYAGYTCNAARYTNYTNMGNCCNGAYGTNACN ATGGAYGGNATGGARGARGGNGARGARGARAGYCARYTNAAYYTNAGYCAYTCNATHMGN YTNGARACNYTNAARAARGARGARGARCARAARTAYYTNACNTTYGTNAARGARGTNACN GAYGAYGTNYTNGCNMGNGGNATHTCNACNGAYAARGTNYTNCAYAARGTNTTYGARAAY CAYATHGARAARMGNMGNGGNGAYYTNGAYGARACNMGNATGMGNGCNATGATHAARGAY YTNAARAARGAYYTNGGNYTNMGNGAYYTNTCNGTNGARMGNAARGARGCNGAYTCNGTN GTNGAYAARGAYMGNTCNACNGARCARTCNGTNCAYTCNGARACNMGNACNTCNAAYAGY AAYATGTCNATGACNATGGARTCNACNTCNACNATGAARTTYGGNCARACNGGNGAYYTN TTYAGYACNATHCAYTCNGAR------------GCNTCNGGNAARGARTCNGAYAARGAR AAYGARAAYGAYYTNACNGCNACNCARGTNYTNAARGARTAYCARATGAAYYTNACNGCN AARGARGCNAGYGTNGAY------------------------------------------ ------------------------------------TTYAARATHMGNCCNATHAARGAR AAYGARTGYGARCARGTNATHGARATGGTN------------------------------ ---ATHGARYTNGCNGARTTYGARAARATGCCNGARTGYGTNAARAAYACNCCNGARGGN YTNAARCARGAYATHTTYGGNCARCCNCARMGNTGYCAYTGYYTNGTNGCNGARGAYACN AARAAYAARGARTCNGGNATHGTNGGNTAYGCNYTNTAYTTYTTYCCNTAYTCNACNTGG GARMGNACNTTYATGCAYYTNGARGAYYTNTAYGTNAARCCNGAYTAYMGNGGNAARGGN ATHGGNAARAARATGTAYCARGCNTGYACNCARATHGCNATHGAYATGGAYTGYAARMGN GTNCARYTNGAYGTNYTNGGNTGGAAYAARACNGCNAARGARTTYTAYGARMGNGTNGGN AAYGARGAYAAYACNGARACNGARGGNTGGCAYAARATGMGNATGAARMGNGARCARATG GARAARTTYGTNAARTCNAGYTCNTCNTCNATHYTNTCNMGNCAYMGNGARYTNGAYTCN CCNMGNAAYTCNAAYTCNGTNTTYAGYTCNAGYCAYTCNGARAAYGTNACNCARCCNGCN TCNCCNMGNYTNGGNGGNAAYTCNYTNMGNCCNGCNGGNTTYTCNGTNTTYAARGAYTCN TCNACNATGTCNAGYTCNMGNTTYMGNGAYAGYGAYMGNGCNGTNGGNGGNAGYCARGGN TCNGAYTCNATHCAYTCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG TCNGCNACNATGTAYTGGGGNGARATHCCNGARATHTCNGAYACNGARTCNGGNATHGCN GCNYTNGARMGNGARCARATHACNMGNCCNAARCCNATGGAYGTNGARGGNCAYYTNYTN CAYCARCCNTCNAAYMGNCAYCAYCCNCCNACNAAYGARATHYTNCCNAAYGAYCAYTTY AARATGGAYCCNGTNGTNYTNCAYACNATHMGNYTNYTNCARCAYATHAARAARGTNMGN GCNGCNATHGARTCNYTNCARAAYGAYATHAARTCNGARTCNGARCCNGCNGTNATHAAY GTNGGNCCNGTNCCNGARTAYGAYGGNCCNCARATHAARGAYMGNTCNCAYCARAARTAY TTYACNGARGARGARTAYGARAGYGAYTTYGTNAARGGNGTNCCNAAYCCNCARCCNCCN ATHGAYGARTCNACNTGYMGNMGNYTNYTNMGNMGNTCNACNGCNGCNATHTGYGCNCAY YTNTCNATHGAYACNGTNCCNGARTCNGTNYTNGAYACNYTNACNGAYGTNTGYCARGAR TTYTTYTCNCARTTYACNMGNCAYYTNGGNTGYGCNGTNGAYMGNMGNGCNYTNCAYGGN AGYAAYGGNTTYCCNGAYTCNATHGARMGNGTNYTNCAYGARATHGGNATGGGNAGYGTN ACNGARYTNCAYACNTTYTAYCARCARMGNGTNYTNGCNTAYCAYAGYMGNATGGARMGN CAYTGYCARTCNYTNATGACNGARTAYAAYACNYTNATHAARCARCCNCAYCCNTCNTCN AARCARGTNTCNAGYTCNCCNAAYATGACNGGNGAYACNYTNCARGTNATHMGNATHAAR GARGARCCNAAYACNTCNATHCARTTYCCNYTNYTNGAYGAYAARGAYGAYGTNGCNGAR GCNGARCARYTNYTNAAYATHGARAAYYTNGGNCCNTTYGARATHGTNGARCARGARATH CCNACNGGNYTNACNACNGARATGAARGCNAARGGNATGCARGCNAARGGNAGYGGNGCN GARAGYMGNGCNGCNAARATGTCNATHTGGAGYTCNGTNGAYGARTCNAGYGAYGGNAGY AGYAGYGAYATGACNGCNGTNACN---------------ACNCCNCARTCNGGNATHCCN ACNACNCCNCARGAYTCN---------ACNCCNMGNGARGGNGGNTCNACNGAYGAYYTN CCNATHCARGARCCNGGNTCNATHAGYAGYGCNGAYATHTTYTCNCCNACNATH---GCN GGNCCNAGYAARCCNAARAARAARAARAARGCNAAYCAYTGYAGYAARAGYGTNGCNACN TCNGTNAARGTNAARCCNAGYATHYTNYTNTCNAARACNAAYGCNYTNGTNGAYGARGAR GTNTGYATHACNGTNAGYGGNYTNCARAARGGNCARAARGTNACNYTNCARATGCAYGTN GAYGARGGNAGYAARAGYTTYGGNGCNTGYGGNCAYTAYGTNGCNGAYGARAAYGGNAAR TTYAAYACNATGGARCAYGARAGYAAYGGNGGNACNTTYAARGGNTAYGAYGTNGAYMGN TGGGCNYTNACNYTN--------------------------------------------- ---------------------------------------GGNTTYNNNAAYTTYTCNCAR ---------------------------------------------------TGGTAYATG AAYCCNAARGTNAARATHATHCCNGTNGAYGARGAYGGNGTNTTYGGNACNYTNTAYYTN CCNGARGGNGARGGNCCNTTYCCNGGNGTNATHGAYGTNTTYGGNATHACNTCNGTNAGY CCNGGNCAYMGNTCNTCNYTNYTNGCNTCNAARGGNATHGCNTCNTTYAAYYTNACNTAY ATHGGNATHMGNGGNACNGCNCARTCNACNGARGGNATHGAYTAYACNTAYTTYYTNMGN GCNTTYGAYTGGYTNTCNMGNCAYCCNAGYATHAAYCCNAARGCNYTNGGNGGNATHGGN AGYTGYATHGGNGCNGCNTAYYTNTCNATHATHGTNTGGAARMGNCCNAAYYTNMGNTGY TAYGTNAGYATHAAYAGYCCNACNMGNCCNGARGGNCCNACNCARATGGTNGARGGNGAR YTNGTNAAYGTNGTNCCNTGGYTNTGGCAYYTNMGNGARGARATHGARGGNGCNYTNTCN TGGMGNCCNATGGGNMGNGTNGARGAYAAYGTNCCNTCNYTNCCNTAYTGGMGNCAYGGN GCNAARGTNYTNCARATHCARGGNGARGAYGAYMGNTGYGTNAAYCCNGAYTGYYTNMGN GCNAGYCAYAARGTNATHCCNCARCARTTYATGGAYAAYGTNAARTTYATHAGYTAYCCN GGNGCNGGNCAYATHYTNGARCCNTCNAAYATHCCNYTNTGYCARAARAAYTAYAAYGCN ATHTTYAARACNATGATGYTNTGGGGNGGNCARCCNAARCARCAYGCNCAYGCNCARGCN GAYTGYTGGCCNAARATHATHGARTTYTTYAARAARAAYYTNAAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GGNYTNTAYACNTGYCARATHAAYACNGARCCNATHMGNATHAARYTNGTNTAYYTN AAYNNNCARNNNCCNTCNNNNNNNATHNNNMGNNNNTCNNNNNNNAANNNNACNNNNNNN GGNNNNNNNNNNACNYTNNNNTGYAAYGCNNNNNNN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TGYGGNGTNGTNTTYYTNGCNCCNGTNTCNGARMGNYTNGGNGGNAARCCNGTN ATGYTNGTNTGYYTNTGGYTNCARGCNATHGTNGGNACNATHYTNCCNTGGGCNGGNAAY ATHGCNTTYTTYATGGTNYTNAARTTYTTYATHGGNATHTTYAAYATGACNATHGCNYTN TGYGTNGCNGTNYTNATGCAYGARACNTTYGAYTCNACNCAYMGNGARATHCCNTCNATH GGNGTNCARTTYTTYTGGGCNTTYGGNATHATGAGYYTNTCNYTNTTYGCNTAYYTNATH CCNGAYTGGAARGTNYTNCARYTNGTNATHACNYTNCCNGTNCCNATHYTNAGYATHGCN TAYATHTGGATHATHCCNCARTCNYTNCCNTGGYTNGTNTCNAARGGNAARYTNAARGAR GCNGCNMGNGTNATHMGNMGNTTYATHAGYATHAAYAAYYTNCCNTCNATHCCNAAYYTN GAYGAYATHYTNATGAGYTTYAARAARAAYCAYGTNTCNGCNCARGARTCNAGYATHTCN GAYAAYAGYYTNAAYACNCAYYTNMGNGAYCARGCNYTNTCNGARCCNAAYCAYATHCAR GGNAARACNTAYACNGTNYTNGAYATHTTYAARGARYTNTTYMGNGGNTTYYTNGTNTCN GARCAYAGYGAYGARAAYATHGARTTYTGGATHGCNTGYGARAARTAYAARGTNGTNAAR TCNCAYAARCARYTNGCNCCNYTNGCNCAYAARATHTTYAAYGAYTAYGTNGCNGTNCAR TCNMGNMGNGARGTNAAYYTNGAYTCNACNACNMGNAAYTCNACNGARAGYGTNACNTCN AAYCCNAAYMGNCARACNTTYGAYGCNGCNCARAARMGNGTNCARGCNYTNATGGARAAR GAYTCNTAY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATGCAYCCNTAYTAYTAYGTNCARTAYGTNCCNATHCCNYTNAARCARGAYYTNGAR ATGAARGTNAAYTGGGCNGCNTCNCCNAGYACNGCNCCNAARCARGAYACNAGYAARCAY TTYCAYGTNTTYGTNGGNGAYYTNAGYTCNGAYATHGARCARCAYCARYTNMGNGAYGCN TTYTCNATGTAYGGNGARATHTCNNNNTGYAARATHATHMGNGAYCCNGCNACNATGAAR TCNAARGGNTAYGGNTTYGTNTCNTTYGTNAAYAARGCNGARGCNGARACNGCNATHAGY GGNATGAAYAAYCARTGGYTNGGNACNMGNCCNATHMGNACNAAYTGGGCNACNMGNAAR CCNYTNGCNCCNATGGTNAARGARAAYGCNAARCCNYTNYTNTAYGAYGARGTNTTYGGN CARTCNAGYCCNACNAAYTGYACNGTNTAYTGYGGNGGNGTNACNAAYGGNYTNACNGAR GARYTNATGMGNAARACNTTYTCNCARTAYGGNACNATHCARGARGTNMGNGTNTTYAAR GAYAARGGNTAYGCNTTYATHMGNTTYAGYACNAARGARGCNGCNACNCARGCNATHTGY GCNGTNCAYGGNACNACNATHAAYGAYCARCCNGTNAARTGYTCNTGGGGNAARGARTCN AAYGARGGNAGYCARACNAAYCARCARTCNAAYAGYCCNCCNGTNGTNATGGTNCCNTCN CARCARCARCARCCNATHGCNGCNACNCCNGCNGCNGCNCCNTAYGGN---CARTTYTAY AAYATGAAYTAYTAYCAYGGNGCNCCNTAYGCNGCNGGNACNCCNACNTAYCARAGYGCN GTNCCNGCNCARGGNCARTTYATHCCNACNGCN---GGNCARTGGCCNGGNGGNTAYTCN AAYTAYCARGCNTAYGGNAGYATGAAYGTNCCNGTNGGNCARTAYGCNGGNYTNCARATG CARCCNGGNGCNCARCARCARCARTTYAGYGGNCARGGNCARGGNATGGTNGGNTAYCCN ATGCARCARGGNATGGCNMGNTCNAAYGTNMGNTAYGARGTNYTNCCNTCNGARGARCAR AAYGTNGCNGCNGARCCNGTNGAYYTNGCNATGGTNGTNCCNCCNCCNAGYTAYACNGAR AAYGCNGTNATGGARCARGAYGGNGARAAYCCNGCNTTYGGNCCNGCNAARYTNCCNAAY TAYGTNGAYGCNACNACNYTNCCNACNTAYGARGARGCNGARMGNAGYAARGCNGARGAR ------TCNGCNACNTCNAGYAAYCARGAYTGYGARACNGGNMGNATHACNTCNATGGAY GGNATHAAYGARGCNACNATHGGNACNGAYGGNATGTTYATHTGYACNTTYTTYATHTCN TTYYTNTTYAAYTGGYTNGGNTTYYTNYTNTCNYTNTGYYTNTCNAAYACNATHGCNGGN MGNTGYGGNGCNYTNTCNGGNYTNGGNYTNTCNATHGTNAARTGGGTNGTNATHGCNAAR MGNAAYAAYTGGGGNACNGAYTTYGCNGAYGGNGAYTCNTGGYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GGNCARTCNTTYGAYGTNTTYGTNCCNGTNTCNAAYTGYACNYTNGAYGTNATH YTNMGNACNGCNTTYTCNTAYMGNTCNAAYTGYCARACNGCNGGNGAR---CARCARTAY ATHAARAAYYTNACNGARYTNATHTAYYTNTGGACNTAYMGNACNTAYACNCCNAARGAY TTYAAYGARTTYATHTAYGGNYTNACNTCNMGNGGNAARMGNTTYTAYAARYTNTGYGAY GARGTNCAYGARTTYGCNGARGARATHATHGAYMGNMGNMGNGCNACNYTNGARGARTCN AAYCARAGYAAYATHGARAAYACNTCNAARGTNAARGAYTTYYTNGAYACNYTNYTNATG GCNAARGAYGARAAYGGNAAYGGNATGACNMGNYTNGARATHMGNAGYGARGTNGAYACN TTYYTNTTYGARGGNTTYGAYACNACNACNAGYGGNACNGCNTGGTCNYTNTAYAGYYTN GCNTCNCAYCCNGARTGYCARGARMGNGTNTAYAARGARATHATGGARGTNYTNGAYGGN MGNGARGARYTNGARTGGGCNGAYATGACNAARYTNGARTAYACNACNATGTGYATHAAR GARGCNATGMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AAYYTNAARGCNGARTCNTCNGCNTGGAAR AAYMGNTTYTGYATGGCNAARGAYGARTCNGAYMGNYTNACNGAYGAYAAYMGNGCNAAR GAYGGNCAYATHCARAAYYTNACNACNCARYTNCAYGARACNYTNCARCARACNYTNGCN YTNCARAARGCNYTNTTYACNAGYTGYGARMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TCN CARGARATGGARATHGAYYTNATHAAYMGNGAYCCNAAYAAYYTNAAYGAYCAYGTNMGN GTNTGYTTYGAYGARGTNATHGGNGARCCNGAYGGNGCNCAYTCNATHAAYTGYGTNTGG ACNAAYAGYTAYAARTGYTTYAAYTGYTGGAARAGYTGYTGYTAYAAYYTNYTNACNATH TTYTGYGCNATHCCNATHTCNATGTGYTGGGGNTGYGARTTYGCNTAYATHACNTTYATG CAYGTNTGGGARATHACNCCNTGYATGMGNGCNTAYATGATHCARTGYGGNTGYATGCAR AARTTYTAYGGNACNTGYYTNCARTGYTGYATGCARCCNTGYTTYGARGCNATGGGNTTY TGYTTYAAYAAYATHAARGTNACNAAYGTNAGY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATGTCNACNTCNAARATHTCNGCNAARGTNTCNAAY TGGAAYCARGARACNAARGCNMGNYTNAAYGARAARATHACNTCNAAYGTNAAYGAYGTN GGNTCNYTNGTNMGNCARYTNATHMGNGGNTCNAARACNAAYGARTTYYTNGCNCARGCN GCNAARAAYTTYGCNTCNCARGARAGYTAYATHCARAAYTCN------------ACNGAR ACNATGAARAARATGGAYGTNGTNMGNTCNCAYYTNGARTTYCAR--------------- ---------------------------------CARTCNTCNATHTCNMGNAGYYTNCAR CARYTNGAYGARGTNCARGAYCARYTNTCNACNYTNCARCAY------------------ ------------------ATGAAYAARCCNGGNGAYCAYGTNGTNYTNGTNCAYTGYTCN CARTTYCARYTNCAYATHGGNYTNCCNGGNYTNGCNGTNAAYGTNGARCAYGTNAGYAAR CARGTNCARGARGCNAARGAYAARTGYGAYGARATHATGAGYAARGCNACNGCNATHYTN MGNGGNAARGAYATHCARGCNTAYACNGTNATHAARAAYAGYCARAARCCNCAYGARGCN YTNYTNGARGCNGCNAAYGARGARAARGTNGAYCAYATHATHATGGGNACNMGNGAYYTN GGNGCNATHAARMGNGCNTTYATHGGNAGYGTNAGYACNGARGTNGTNMGNCAYGCNGCN GTNCCNGTNACNATHGTNAAR---------ATGGAYAAYYTNAGYYTNTCNGGNAARGTN GCNATHATHACNGGNAGYAGYTCNGGNATHGGNMGNACNGCNGCNATHYTNTTYGTNAAR MGNGGNGCNAARGTNACNYTNCAYGGNMGNAAYGARGCNAARYTNCARGCNGTNGCNGAR GARTGYAARAARGCNGGNGGNAARGGNAAYCARGTNYTNATHGTNGCNGGNGAYGTNACN ACNGARGCNTGYMGNAARGCNYTNGTNGARAARACNGTNAARACNTTYGGNCARYTNGAY ATHYTNGTNAAYAAYGCNGGNMGNYTNYTNGCNGARCCNYTNMGNGAYATHACNGARAAR GGNYTNGAYACNATGATGGAYYTNATGTTYAARGCNCCNATHTTYYTNTCNAARGCNGCN YTNCCNCAYYTNAARAARACNAARGGNTGYATHGTNAAYACNTCNACNACNYTNACNACN GARAAYTTYCCNGGNTTYTTYTCNTAYACNGTNGCNAARCAYGCNATHGAYAARTTYACN GARTAYGCNGCNYTNGARTAYMGNTCNGCNGGNATHMGNGTNAAYACNGTNAARCCNGGN ATHACNGARACNAAYATHTTYAAYGARGTNTTYAARGGNGAYGCNAARCARGTNAARGGN TTYYTNGAYGGNCARAARGARCAYTCNATGCARGGNMGNTGYGGNCAYCCNGAYGAYATH GCNGARATGATHGCNTTYYTNTCNTCNAARGCNGCNAGYCAYATHACNGCNCARCAYTTY GTNGTNGAYGGNGGNMGNGCNAAYTAYTTYCAYCAYGGN--------------------- ------------MGNGARATHAAYMGNMGNYTNGARAARTTYYTNAAYAARMGNAARCAR TTYCCNGAYTTYCARGAYGTNAARACNATHATHCARYTNACNAAYAARAARTGYAAYYTN CAYYTNAGYACNCCNYTNATHAAYGAYGTNGCNMGNGARGCNTTYGTNGAYATHGGNGAY ATGYTNCARACNMGNMGNCAYCARGAYTTYATHGCNACNTTYGGNTCNMGNCARACNGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYGAYGAYGAYGARGTNGAYGARGAY AARGAY---GARAAYGARAARYTNAARGCNCCNACNGARYTNYTNATGGARTTYATHGAY TGYYTNATGAARAARGAYTAYCCNAAYGCNAGYAARYTNTGYAARATGATHYTNYTNTTY GARCCNGARAAYGARGARGCNYTNAARTTYCARCCNYTNATHGARGARAARATGGCNYTN GAYGCNGARGCNGCNGARGARGGNAGYAGYGAYGAYGARGAYGAYGAYGAYGAY------ ------------------AGYAAYMGNYTNGTNTGGGTNGAYYTNGARATGACNGGNYTN GARGTNGARAARGAYCAYATHYTNGARATHGCNTGYYTNATHACNGAYAARGAYYTNTCN ATHGTNGCNGARGGNCCNGAYYTNGTNATHCAYCARAGYGAYGAYGTNYTNAARGGNATG ATHGARTGGTGYATHCARCAYCAYGGNGARTCNGGNYTNACNGARGCNTCNAARAAYTCN AARATHGAYYTNGGNGARGCNGARAARATGGTNYTNGARTTYGTNCARCARTAYACNCCN AARGGNGARTGYCCNATHGCNGGNAAYTCNGTNGGNATGGAYAARMGNTTYATHGAYMGN TAYATGCCNYTNYTNGCNGARCAYYTNCAYTAYMGNGTNGTNGAYGTNAGYACNTTYAAR GARGTNTGYMGN---------------------------------MGNTGGTAYCCNGAY GAYTTY---AARTCNGCNGCNAARAARTGYMGNCAYMGNGCNATGGAYGAYATHMGNGAR AGYATHGARGARYTNAARTAYTAYMGNAAYAGYATHTTYAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GGNGTNAAYATHAGYGARGCNACNYTNGTNTAYTCNAAYATHGCNACNTCNYTNCCNTGY YTNYTNAAYCCNYTNYTNTAYAGYYTNATHYTNGCNMGNTAYMGNGARGGNTAYAARGCN ATHYTNGARMGNTGYMGNMGNAARAARGGNCCNCARAARCCNCAYMGNYTNMGNAAYGTN CARTAYTGYTGYGAYMGNGAYTCNACNACNGAYGCNGAYATHGTNTCNTCNATGGAYGGN CAYMGNTGYGCNCAYGGNMGNCCNAAYCCNACNTTYGAYYTNACNTTYYTNGTNGTNCAY CCNGTNGTNAGYMGNCARATGTGYTAYACNTGYCARTAYGTNYTNAAYGGNCCNGGNATH GARTGYGTNACNTCNCCNYTNAAYTGGACNGGNGGNCARCCNMGNATGMGNTGYCCNAAY MGNTGYACNACNYTNGCNGARTAYGAYTCNAAYACNGGNAARCCNACNTTYTTYTTYMGN GGNTGYGCNTCNYTNGCNAAYGGNCARAARGAYGGNTGYCAYGAYAAYGGNCCNMGNCAY AGYTGYTTYTAYTCNTGYGGNGAYGGNCAYGAYTAYTGYAAYGAYAARTCNYTNCCN--- ---------GTNTCNCCNATHTTYGGNCARGGNGARGAYGGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------TTYATHGCNTCNGGNTCNYTNATHGTNGCN GTNGGNTTYGTNTCNTGYGARAAYMGNATHACNGGNATHGTNYTNYTNACNYTNTCNGTN GGNTTYGARGGNATGGTNTAYGGNGGNTAYATGGTNAAYCAYGTNGAYTTYGCNCCNGGN TAYGCNGGNGTNGTNTTYGGNATHACNAAYTTYGTNTCNACNATHCCNGGNATGYTNGCN CCNATHGTNTTYGGNGCNYTNACNCCNAAYAARACNCARGARGARTGGMGNAAYGTNYTN TAYGTNTGYGGNGCNTTYGTNYTNTTYGGNGCNGTNGTNTTYGGNTGYTTYGCNCARGGN GARACNCARCCNTGGGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ACNCCN GARGTNGARAARAARAARGAYAARGAYMGNCCNCCNTCNAARATHGTNATHMGNMGNYTN CCNCCNTCNYTNACNCCNGARAAYTTYYTNGAYCARGTNTCNCCNYTNCCNGAYCAYGAY TTYTTYTAYTTYGTNMGNGCNGAYYTNAGYYTNGGNCARAAYGCNTTYTGYMGNGCNTAY GTNAAYTTYYTNAAYGCNGARGAYATHTTYATHTTYMGNGAYAARTTYGAYGGNTAYGTN TTYYTNGAYGARAARGGNGGNGARTAYCCNGCNGTNGTNGARTTYGCNCCNTTYCAYAAR GTNACNAARAARMGNCARMGNAARGTNGAYTCNAARTGYGGNACNYTNGARCARGAYTCN GAYTAYAARMGNTTYYTNGARATGYTNGARAAYCCNCCNGARGCNCCNTCNGTNTCNYTN GAYGCNATHGTNGARGARGTNGARGCNAARGARYTNMGNYTNGCNAARATGGGNACNACN AARACNAAYACNCCNYTNYTNGARTAYYTNAARMGNMGNAARGARGARAARMGNATGAAY ATGGTNAARYTNMGNGAYGARMGNMGNMGNGGN---GGNMGNGAYMGNGAYTAYGAYMGN MGNMGNTCNGCNAARGARGAYGGNAGYAGYMGN--------------------------- AARGAYMGNGAYMGNGAYMGNCARYTNGAYMGNGAYMGNMGNAARGARMGNGCNMGNGAR ATGGCNMGNGARAARGARMGNGARMGNMGNMGNGAYMGNGAYMGNGGNMGNGGNGGNGGN AARCARMGNGARMGNMGNAAYGARGGNGGNAGYGGNMGNTAYMGNGARGCNGAYGARAAR AARCCNATHATGYTNYTNAARAAYACNGARMGNGARAGYCARGCNGTNGAYGARCCNTCN CARGAYMGNATGAARGGNGAY------------------------MGNGARGAYGGNMGN TAYGGNAAR------------MGNGGNGGNGGNGGNGGNGAYAARTGG------------ ---------------AARAARGGNGAYMGNGARMGNGAYMGNMGNMGNGAYTGGGAYGAR MGNCCNCCNAARTCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ CCNTCNGTNGARGGNAARACNTTYAARATHMGNTAYGGNYTNGAYGTNTCNGTNAGYTTY AGYAAYGGNCAYACNGARACNYTNAGYYTNGTNATHCCNGGNGTNYTNCCNCARGCNAAY AARAARTGGTCNTCNTGGMGNGCNCAYGAYTGGYTNTTYAAYTGYGAYACNAARYTNTCN AGYTCNYTNTTYTCNGTNTCNGARCARYTNYTNTAYACNGARGCNTTYTCNAGYATGCCN AGYTTYCARGTNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AARGGNGGNTTYACNTGG ACNATHATHCCNGGNYTNATHGCNCCNCAYGTNGGNYTNATGYTNGGNTTYTAYTCNATH AAYGAR---------ATHMGNGGNGGNGGNGARYTNTTYAARTTYCCNTGGACNACNTAY TCNAARGTNCARCARTTYCCNTTYAARTTYTAYTGGAARCAYGTNMGNGTNTTYMGNTAY TTYTTYTAYACNTCNGCNYTNGTNTTYCCNYTNATGGTNAARYTNACNAARGCNACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNMGNCCNGCNCARCCNTTYATHYTNGCNGCNCCN MGNYTNCCNCCNCCNACNGTNGTNGCNTCNAGYCARCCNAGYYTNAAYGGNACNGCNCCN CCNCCNYTNGTNTCNCCNCCNCAYGARGCNACNGGNYTNGTNTAYAAYCCNTAYGCNATG GGNAGYATGGGNTCNTCNACNACNGCNATHGCNTCNCCNGTNGAYCCNTAYGGNYTNGGN GCNGCNACNCCNCARGCNGGNGCNGTNCCNAARATHMGNMGNACNYTNGARGGNGTNMGN GGNCAYCCNTAYACNMGNGTNTCNYTNTCN---GCNGAYACNYTNCARYTNYTNAARTGY GGNGTNMGNTTYAAYCCNCCNACNYTNGTNATHACNTAYAARGAYTGGAARTCNGGNAAR ATGMGNMGNMGNTCNATGCCNYTNMGNAAYTTYACNAARCAYTCNGGNATHGARMGNGTN TGYGAYGAYYTNAARGARAAYCCNMGNCAYGCNAARTTYATHMGNYTNYTNTCNCCNYTN CARYTNCARMGNYTNYTNACNATHGTNAARGAYAARATHAGYGGNYTNAGYYTNGARGCN AGYATHGCNMGNAAYAARGARATGGAYACNYTNAAYCCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------- >venustus ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARCCNYTNCCNGCNTAYTGYAAYCCNCCNAAYCCNTGYCCNATHGGNAAR ACNGCNAARGAYAAYTGYGTNGARGAYTTYGARAAYTCNGCNGARAAYAAYAARAARYTN YTNAGYGARCARGARTGYCCNTGYGAYACNGARCAYATGTTYAGYTGYCCNGCNGGNAAR GARACNGTNTCNTCNAARGGNCARTCNGGNTAYCARCARACNYTNAAYAARGTNATHGAY CARYTNTCNAARATGGAYACNGAYGAYGARGARGARAARGCNGAY---------TCNGTN GAYTGGAARCARGTNAGYYTNGTNGCNAARAARTCNCCNCAYATHATHCAYAARMGNGCN GARGCNGCNGAYACNCCNAAYCCNTAYYTNATGGGNACNMGNATGGAYATHGCNGCNAAR AARAAYCARCARATGTCNCAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GTNYTNTTYGGNYTNTCNCARYTNYTNTCNGCNTCNTCNATHGARGAY AARTAYGARCCNATGGTNGCNTTYATHTGYGGNMGNCCNGCNATGCAYMGNGGNGTNAAY GGNTGGATHGCNGAYAARTCNCARAAYTGYCCNGAYACNYTNGARGAYGTNYTNTCNTTY TGYCARAARAGYTAYCCNGAYCAYAAYATHACNAAYGTNGTNGARTCNTCNMGNYTNTAY GAYATHCCNAAYTGGCCNATGGGNAAYGCNGARMGNCARCAYACNCAYCAYATHMGNCCN TTYMGNTGYYTNGTNGGNAARTTYCARTCNGAYGCNYTNYTNGTNCCNCARCAYTGYGAR TTYGAYCAYMGNCAYGAYATHACNCARTGYAARGCNTTYTCNCAYTGGAAYMGNGTNGCN GAYGARGCNTGYGAYAARAARGGNATGCAYYTNGARTCNTTYGGNATGYTNYTNTAYTGY MGN---YTNGGNCAYTTYAAYGGNGTNGARTAYGTNTGYTGYCCNAAYCCNTCNGARACN CAYGTNCAY------CCNGARCCNGCNGGNGAYGAYAARCCNGAYCARTGGGGNGAYAGY AGYACNCAYACNCARGARGAYAAYGAYGCNGARGARAARGARGARGTNTCNCCNGTNGCN ---------------------------------------GCNGCNAARGTNAARGAYACN GCNGCNTCNGCNGCNYTNCCNGAY------GARGARGTNGCNGAYYTNTAYGARGCNTAY YTNMGNGGNYTNCCNTTYCCNATHAARTAYGAYAAYGARCAYAARAARTTYYTNGCNGCN AARGAYMGNATGMGNAARAAYCARAARAARMGNGTNTCNAARYTNYTNCARCARTGGGAR AARGARMGNGARMGNGTNAAYGARATHAARAARACNGAYCCNAARGCNGCNGAYAARATG AAYCARGARATHGCNGCNMGNTTYAARCARYTNTAYAAYTCNTTYAARCARGARGAYGAR GCNGARACNCARCARYTNYTNGCNYTNCAYCARCARCAYATHCARGCNTCNYTNAAYGAR CAYAARMGNGARGCNATGGAYAARTAYATGMGNGCNYTNGARGCNGGNGARAGYGCNAAR ATHACNCAYTAYYTNCAYAAYTAYATHAARGCNGARGARAARGAYMGNATGCAYACNGTN AAYCAYTTYGARCAYYTNMGNTAYTCNGCNCCNAARGARGCNYTNMGNATHCAYCARCAY ATHATHAAYCAYYTNAARYTNTCNGARYTNMGNATHGAYCARGCNATGGARATGYTNACN CAYTAYCCNGARATHGARGTNAARGTNMGNCCNGARGTNGARGARTTYYTNAARMGNTTY AAYGCNATHGCNACNAGYATHAARGAYGTNGTNYTNCCNGTNCCNCARGTNGARGARGAR TCNGARGARGGNAGYAGYAGYCAYGARTCNTAYGAYGAYTCNTCNGAYGARGCNTCNTCN TCNTCNGAYMGNAGYAGYAGYGARGCNGGNGGNTAYGAYAGYAAYGAYAGYCARTAYATH ACNGAY------------------------------------------------------ ---------------------------GAYGARGTNCARGARGAYGARCAYAGYTAYGAR MGNCARCAYCAYTTYGARGCNAAYGCNATGTCNAAYATGCARAGYGCNGAYCARGGNYTN AARTCNGTNGCNAARGCNGGNAGYCARGTNGGNAGYAGYGTNGGNATHGCNYTNGGNAGY GTNTCNGTNTTYGTNATHATHGTNGTNGCNGTNATGATGATHAAYMGNAGYAAYAAYMGN CARTCNGTNTCNCAYGGNTAYGTNGARGTNGAYCCNTCNGCNTCNCCNGARGARMGNCAY YTNGCNAAYATGCARATGAAYGGNTAYGARAAYCCNACNTAYAARTAYTTYGAR------ ---AARGAYAARYTNTAYMGNCARATHACNGTNGARGTNAARGGNCAYGAYCCNTCNGTN ATHAAYAGYTAYCARAARTTYACNACNATHGCNGCNGARCARYTNGGNGTNAARYTNGAR AGYATHTCNGARCCNCCNAARGTNATHTCNMGNMGNAGYYTNYTNAARTCNGTNTTYATH TTYAARAARCAYCARCAYCARTAYGARACNMGNACNCAYTTYMGNATHTTYGARTTYAAR CAYYTNACNGARTCNACNGCNYTNACNTTYYTNGARTAYATHCARMGNAAYYTNCCNGAR GGNATGGCNATGAARGTNACNAARCAYGARYTNCARCCNTTYCCNGARCAYATGAARCCN CCNGCNCARGCNMGNTCNGCNGCNCCNTCNCCNTCNGAYTAYTTYAAYGTNATGYTNGGN TCNCARYTNYTNTAYAARTTYGARMGNCCNCARTAYGGNGARATHYTNGCNGARTAYCCN GAYAARCCNATGTCNAGYATHTAYGGNGCNACNCAYTTYYTNMGNYTNTTYGTNMGNYTN GGNGCNATGYTNGCNTTYACNTCNYTNGAYGARMGNACNGTNCAYATHYTNYTNAAYCAY GTNCAYGAYTTYYTNAARTAYATGTCNAARAAYGCNCCNACNYTNTTYAARACNTCNAAY TAYGARATHGCNACNCCNGAYTAYCAYMGNAARGCNATH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ACNAARCARMGNTGGATHCCNYTNGAR TCNAAYCCNATGGTNGTNAAYAARTAYGTNCAYGGNYTNGGNATGGAYGARGGNTGGAAY TTYGTNGAYGTNTAYGGNYTNGAYCCNGAYYTNYTNGCNATGGTNCCNMGNCCNGTNGCN GCNGTNGTNYTNYTNTTYCCNGAYCCNTCNTCNGARACNGTNGCNGARAAYCCNATHGGN GARGTNATGAARGAYTCNCCNGCNGGNYTNTTYTAYATGAARCARACNATHGGNAAYGCN TGYGGNACNGTNGCNATHGTNCAYTCNYTNGCNAAYTCNGARGGNAARATHAARTTYGAY GARAGYAARCAYTTYTCNGCNTTYYTNAARGCNAGYACNGCNATGAAYCCNGAYGARAAR GCNGAYTAYYTNGARAARGAYYTNGCNATGGGNGCNGCNCAYGARGAYTGYGCNCARGAR GGNGAYACNACNGCNCCNGCNGCNACNGARAARGTNAARTGYCAYTTYATHGCNYTNGTN CAYTTYAAYGGNACNYTNATGGARYTNGAYGGNMGNAARGARGGNCCNGTNAGYCAYGGN GCNACNACNGCNGAYAGYTTYATGGARGAYGCNGCNGTNGTNGTNAARAARTTYATGGAR MGNAGYCCNTAYYTNGCNGCNMGNGCNGCNYTNYTNAARGCNGAYCARAGYMGNATGYTN GGNMGNAAYYTNACNYTNAGYGCNGAYGARCARGTNGTNTCNGAYTTYYTNGTNGGNGAR AARAARAARYTNATHGARGCNAGYMGNYTNGGNGGNGCNGARTAYTAYCCNTCNYTNAGY TTYTAYCARTCNAARCCNTTYATHGAYAARTCNTCNATHTAYAARATHATHMGNAARATG CCNAARGGNGCNGCNYTNCAYYTNCAYGAYATGTCNGTNGCNAGYYTNGAYTGGGTNGTN AGYAAYGCNACNTAYMGNGAYAAYYTNTAYATGTGYACNCAYGCNGAYACNGGNYTNYTN ACNYTNCARTTYTTYAARAAYCCNCCNGAYMGNAARTGYAAYTGGCARTCNGTNAARAAR GCNMGNAGYGARGCNTCNTGYGTNGCNAAYTTYGAYGCNAGYATHAARGCNAAYATHAGY YTNYTNGCNAGYGAYCCNTTYACNACNTAYCCNTCNYTNACNAARGTNTGGACNMGNTTY CARGGNTAYTTYGGNCARGTNTTYGGNYTNATHTTYTAYGARCCNGTNTTYMGNGAYTAY TTYMGNCARGCNYTNAARGARTTYCAYGARGAYAAYGTNCARTAYTTYGARATGMGNGGN ATGTTYGAYGGNGTNTTYAAYTTYGCNGGNCAYAARTAYAAYTCNGARGARATHYTNAAR ATGTAYATGGARGTNMGNGAYCARTTYATGCARGARAAYCCNGAYTTYYTNGGNGCNAAR TTYATHATHTCNTCNGTNMGNACNAARCCNMGNGCNGAYGTNYTNAGYCARGTNAARGTN GCNACNATHYTNMGNCARATGTAYCCNGARTCNATGGTNGGNTAYGAYYTNGTNGGNCAR GARGAYCCNAAYCAYTCNYTNYTNTAYTAYAARGARCARYTNYTNCARCCNCARCARCAR ---------------YTNCCNTAYTTYTTYCAYGCNGCNGARACNAAYTGGCARGGNACN GCNACNGAYTAYAAYYTNATHGAYGCNYTNYTNYTNAAYACNACNMGNATHGGNCAYGGN TTYGGNYTNATHAARCAYCCNAARYTNGTNTCNYTNGTNMGNGARAARGGNGTNGCNATH GARGTNAAYCCNGTNTCNAAYCARYTNYTNGGNYTNGTNAARGAYYTNMGNAAYCAYGCN YTNGTNCCNYTNATGYTNGAYGAYTTYCCNATHGTNGTNAGYTCNGAYGAYCCNACNACN TGGGARGCNACNCCNYTNTCNCAYGAYTAYTTYYTNGCNTTYATGAAYATGTGYGGNGAR GAYGCNGAYYTNMGNTTYYTNAARCARYTNGCNATHAAYTCNATHAARTAYAGYGCNATG ACNCARGCNGARAARAARACNGCNATGGTNGCNTGGCARAARAARTGGCARGCNTTYATH ACNAGYACNGCNGCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TGY CCNAAYMGNGCNACNTGYCCNGARACNGCNTGGMGNTCNTTYTGGAARGCNGTNTCNGTN AARTAYGCNGCNAAYYTNAAYGGNAARGTNACNGTNTTYYTNGAYGGNAGYGGNCCNAAR CCNTAYAGYAAYACNAGYATHYTNGGNGCNGAYGARATHCCNCARYTNCCNTCNMGNGTN GARATGGTNGAYATHATHATHACNCAYGCNATHGGNGARAGYGTNACNGARACNTGYGAR CAYGGNTCNTCNATHGAYYTNAARGARGAYYTNAARCARMGNCARYTNGARTGGCAYTGY TAYGAYAAYCCNCCNTCNGTNYTNCAYTAYYTNTGYATHGAYCAYCCNAAYGAYAARAAR TGYAARCAYGARGARGTNYTNTCNATGATGGARCARATHAAYAARATGTGYCCNGAYATH ACNMGNYTNTAYAAYYTNAGYGARACNTCNGTNAAYAAYMGNAGYYTNACNGTNYTNGAR ATHACNGARAAYCCNGGNGTNCAYAARCCNGGNAARCCNGARTTYAARTAYGTNGGNAAY ATGCAYGGNAAYGARGTNGTNGGNAARGARATGYTNYTNTAYYTNATGYTNGCNATGTGY GARGARTAYYTNAAYGGNAAYGAYYTNGTNAARTTYYTNGTNAARGARACNMGNGTNCAY ATHYTNCCNACNATGAAYCCNGAYGGNTGGGARGCNGCN---GAYCARYTNMGNAARACN GGNAARTCNGAYTGGYTNACNGGNMGNGCNAAYGCNAAYAAYGTNGAYYTNAAYMGNAAY TTYCCNGAYYTNAAYGCNAARATGTAYGARAAYGARMGNGARCAYAARGGNMGNAAYAAY CAYYTNGTNAARGTNGARAARGCNATHGCNAAYGAYGARACNYTNCARCCNGARACNMGN GCNGTNATGMGNTGGYTNGCNAGYATHGGNTTYGTNATGTCNGCNAAYYTNCAYGGNGGN GAYYTNGTNGCNAAYTAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------YTNCCNACNMGNACNTCNGAYGAYATHYTNCARGAYACNTCNGGNATGGTN YTNGAYAARMGNCCNAARTAYATGGAYACNMGNMGNGAYYTNGAYGTNYTNAARGAYYTN GTNYTNATGAGYATHCARGARYTNGTNGAYGARGGNMGNYTNGAYTCNAAYGTNYTNCCN ACNGAR------GAYAARGARACNACNAARCCNGTNGARAARMGNAARTAYATGGGNYTN TGYYTNCAYMGNCARGCNAAYCARTTYATHCCNTTYCCNTGYYTNMGNGCNGGNMGNATG AAYTCNGTNYTNGCNATHYTNATGATHAGYTGYGTNGCNGTNATGGCNGAYAAYTAYAAY TGY---CCNAARGARGGNGAYAARTTYGARTGYTTYGARTCNAARGCNGAYTAYMGNGCN TGYYTNTCNGAYGGNAGY------CAYTCNTAYGTNGTNTGYGGNAARTGYATGMGNAAR TGGGARTTYTGY------MGNACNGARGARGCNAARNNNNNNNNNGCNNNNGCNNNNTGY GGNNNNGAYTAYAARNNNACNCCNTGYACNNNNGAYAAYTCNCAYTGGGAYCCNATHTTY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGNTCNGAYGTNATHCCNCARACNTCNATHGAYAAR CCNGTNAAYGTNTCNYTNGAYATGACNYTNATHAAYATHYTNTCNGCNGAYCARGCNAAR AAYGARGTNGARATHGARGTNTGGYTNACNCARTCNTGGAAYTCNGGNATHACNTTYGAR CCNGARCARTTYAAYGGNYTNCAYGAYATHMGNGTNCCNGTNCAYAARATHTGGYTNCCN GAYGTNACNGTNTAYAAYGGN---GARYTNCAYATHCAYGAYAARMGNGTNCAYCAYGCN GTNYTNGGNATGACNGGNAGYACNTAYTGGGTNCCNAARGCNAARATHGTNYTNTGGTGY GAYYTNTCNGAYGARAGYYTNTCNAAYAAYGTNACNTGYACNGCNAARGTNGGNTCNTGG ACNTAYTCNGCNAAYCAYATGTCNYTNAAYGGNGARCCN---MGNTTYGAYYTNGAYAGY TTYATHGGNGARTCNAARTTYGARGTNYTNGARGCNTCNGCNACNMGNGARGTNAARAGY TAYGCNTGYTGYGARGARAARTAYGARGAYGTNYTNTTYAARTTYACNTTYMGNMGNMGN ---AAYGGNGARTAYTTYTAYAARYTNTCNTCNMGNMGNATGMGNTCNAARGARGTNCAR GTNATHCCNTGGGTNGTNTCNGAYAGYAARTAYTCNTTYCARCCNACNCARMGNYTNGAY TCNAAYMGNACNGTNTTYGTNGGNGCNYTNCAYGGNATGYTNACNGCNGARGCNYTNGGN ATHATHATGGCNGAYYTNTTYGGNAAYGTNGTNGARGCNGGNATHGAYACNGAYAARCAY MGNTAYCCNATHGGNTCNGGNMGNGTNACNTTYAGYAGYMGNAARAGYTAYATGAARGCN ATHCARGCNGCNTTYATHGARATHAARACNACNAARTTYACNAARAARYTNTGYMGNGAY YTNYTNTGYTTYAARTAYTTYTGYMGNTCNTGYTGGTAYTGGCARCAYGCNCCNGARACN ATGMGNCAYCAYMGNACNYTNACNMGNAAYACNAARAAYACN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CCNMGNTTYGTNGGNAARMGNACNYTNGAYATGGAYGARTCNGGNGTNGAY GAY------TCNGAYAGYGARGAYGAYGARGAYGAYGARGARGARAAYGGNYTNGGNTTY YTNCARGCNTCN------ATGGGNAARMGNGGNYTNCCNMGNTTYGTNGGNAARMGNGGN MGNCCNMGNTTYGTNGGNMGNMGNGGNGCNCCNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GAYYTNMGNYTNCCNAARACNATHGTNCCNGTN CAYTAYGAYYTNMGNYTNCARGAYGAYCCNGCNGAYTTYAGYTTYAARGGNCARGTNTCN ATHYTNATHCARTGYGTNGARGCNACNGAYAARATHGTNYTNCAYAGYGTNGGNAAYCAR YTNGAYAAYAGYACNYTNYTNGTNGGNGCNAGYCCNAGYCCNAGYMGNACNGTNGTNAGY TAYCAYGARGAYYTNGCNAGYGAYTTYYTNGTNATHCARYTNATHCAYAGYYTNCARGCN AARGARGARTAYGTNYTNTCNATGAGYGTN---GGNGCNYTNMGNAARGARACNGARGGN GGNTTYATHYTNAGYTCNAARMGNGGNAAYMGNACNAAYTAYTCNGTNTGGACNACNTTY GARCCNAAYTTYGCNMGNTAYGCNTTYCCNTGYTTYGAYGARCCNGGNYTNAARGCNACN TTYAAYGTNACNATGGTNMGNAARGCNGAYATGGTNTCNTTYTCNAAYATGGAYYTNYTN TCNACNAGYTGGYTNGARGAYGGNGTNACNGCNGAYACNTTYAGYGARACNTTYAARATG TCNACNTAYYTNGTNGCNTTYGCNGTNGGNGAYTTYGTNGAYACNTCNGCNGTNGCNTCN GAYGGNGTNMGNTTYMGNGTNATHGCNMGNCCNGARYTNAARAAYACNACNAGYCAYGCN YTNAGYGTNGTNCARMGNTAYACNYTNTTYTAYGARAARTAYTTYGARACNAARTAYCCN YTNCCNAARCARGAYYTNATHGCNATHCCNAGY---AGYGGNGGNGCNATGGARAAYTGG GGNYTNATHACNTTYGCNGARGAYTAYYTNYTNTAYGAYCCNGCNGTNTCNAGYGAYACN GAYAARGTNATGGTNACNMGNGTNGTNGCNCAYGARYTNGCNCAYCARTGGACNGGNGAY YTNGTNAGYCCNGCNTGGTGGAAYAAYATHTGGYTNAAYGARGGNTTYGCNGAYTTYATG CARATHYTNAGYGARGAYTCNYTNGAYCCNTCNTAYAGYGARTTYAARATGTTYGGNGTN AAYTAYGTNGARATHGGNTTYTCNGCNGAYAGYACNGCNAGYTCNCAYCCNGTNAAYGTN TCNATHACNGAYCCNCAYAGYATHTAYGCNATHATGGAYGARGTNACNTAYAARAARGGN AGYAGYYTNYTNMGNATGYTNMGNCAYTTYYTNGGNTAYGARACNTTYMGNAARGGNYTN GTNAAYTAYATHCARAARYTNAARTTYGGNGTNGCNACNAAYGARGAYYTNTGGGAYGCN YTNGGNGARCARGCNAARAARGCNATHAAYGTNAARGAYATHATGGAYACNTGGACNYTN CARATGAAYTAYCCNGTNGTNACNGTNTCNAAYGAYYTNGGNYTNGTNCARGTNTCNCAR AARMGNTTYYTNTCNGAYCCNYTNGARGARGAYCCNGGNACNTAYACNTCNCCNTAYGGN TAYCARTGGTCNATHCCNYTNACNYTNACNTCNAGYGTNGARCARACNCCNACNGAYATH YTNTGGATGAAYYTNGGNGARTTYAAYYTNCCNTCNCAYAGYACNGGN---TGGATHYTN GCNAAYACNCARGTNAAYGGNTTYTAYMGNGTNAAYTAYCARACNGGNAAYTGGMGNGCN YTNATHCAYCARYTNAAYACNGAYCAYACNGTNATHTCNGCNATGAAYMGNGCNCARYTN ATHAGYGAYGCNTGGGCNYTNGTNMGNCARGGNYTNGTNCCNCAYCARACNGCNTTYGAY ATGGTNGAYTAYYTNGAYAARGARYTNGARTAYGTNCCNTGGCARGCNGCNCAYTCNCAR YTNAARGAYATGGCNACNMGNATHGCNYTNACNCCNACNTAYGGNTAYTTYCARMGNTTY ATGCARGARAARGCNGCNAGYTCNTTYAARYTNGGNTTYAAYACNACNAAYGGNGGNTAY TAYGAYAAYYTNTCNAARACNAARATHGCNACNGTNGCNTGYACNTAYGGNYTNGAYTCN TGYGTNACNGARGCNAARAARCARCAYCARGCNTGGATGAARGAYAAYAAYAARCCNGAY MGNAGYYTNGCNTCNGTNGTNTAYTGYATGGGNGTNAARTAYGGNGGNTGGAARGARTGG CARTTYAAYYTNAARATGTAYAARGARGCNYTNATGGTNACNGARAARACNATHYTNYTN GCNTCNYTNTCNTGYTCNMGNGARCCNTGGATHYTNTCNATGTTYYTNAAYCARTTYYTN CARCCNAAYTCNCCNATHCCNAGYCARTTYCCNACNGCNTTYYTNGCNGTNTCNAGYTCN GCNGTNGGNMGNGCNGTNGCNTGGMGNTTYTTYMGNGARAAYTAYGAYGCNATHGTNAAR MGNAAYTAYCCNATHACNATHGGNYTN------------------GCNACNACNACNTTY AAYACNGARAGYGAYYTNGCNGARATGCARGCNATGGCNGGNAARGARGAYCCN------ ---------AAYATGGARGGNGCNGTNGCNGAYGTNACNGGNAAYATHCARTGGYTNAAR GAYAAYTAYGAYATHATHGCNMGNTGGTTYATGACNACNMGNGGNAAYCCNTCNATHTCN CCNCCNGTNCARATHCARCARCCNMGNCAYGTNTCNGGNATHCARTCNGGNACNCCNCCN CCNAAYCARCARYTNTAYCAYGGNCARTCNCARGGNYTNGTNCARGGNACNTTYAAYTAY ATHCAR---CCNCARTAYCCNCARGGNGARCARYTNYTNTCNTAYCARGCNTAYGGNAGY GCNCCNAAYGAYYTNMGNGCNGCNACNGCNCCNAGYGGNMGNGGNGGNACNGGNCCNGCN AAYATGGCNCARCCNGGNGCNTTYTAYCAYCARCCNAAYCARAAYATGMGNCCNTCNCAR CCNCCNCCNCCNAAYCARACNCARCCNTAYTAYATHGGNCCNTCNGGNCARGGNGCNATG MGNCAYGCNMGNCCNGCNCAYCCNTCNAAYCARGCNATGTAYATHATHCCNCARAAYAAY AAYATGGTNATGCCNGCNAAYATGTAYCARGCN------MGNATGCCNYTNTAYCCNGGN CARGGNGGNATGATGTAYTTYGGNAAYGGNATGCCNMGNGGNCCNTCN------------ GTNYTNATGCARACNCCNGGNATGGGN------CCNCARCCNGCNCCNMGNGARAARMGN YTNATHACNATHAGYGAYCCNAAYACNGGNMGNAAYATHACNGAYGARYTNATHAARTCN CARCARCCNACNGARGARAARGGNGARYTNGAYGARTCNTCNGCNAAYGAYAARGGNGCN GARATHMGNAARAAYTTYACNMGNCARGTNGTNGARMGNATGAARACNGGNGARACNGCN TCNTCNTCNCAYCARCAYCCNGCNGARTCNGTNCCNAGYGCNTAYACNCCNGGNCCNCCN CCNCCNCARCARCARCARCARCCNGGNCCNGGNTCNATGATHMGNCCNTCNATGMGNATG CCNAGYCCNGGNGCNATHAAYYTNAARACNTCNCCN---------GCNACNCAYGARGTN CARCCNGTNGARMGNAARCCNATHCCNGCNMGNGCNGARCCNACNATHCCNCARAGYGAY ATHCCNACNCARYTNGCNACNTTYCARGARAAYTCNTCNCARTCNTCNGTNAAYCARAAY CCNGCNGAYCAYGTNTCN---TCNACNACNACNCCNCARAAYGCNTCNGTNCCNACNCCN GCNCCNGTNTCNATGTCNGCNCCNGTNTCNACNAARCCNACNGCNGTNTCNAARGAYGTN CCNGTNCCNGTNGARGARAARCARCCNAGYCCNGARCCNGCNAARCCNCCNGTNGTNGAR GTNCCNAARCCNGTNGARACNACNAARYTNAARACNGCNGARACNGARACNGCNCCNGGN ------------------------------------------------------AARGAR GARGCNACNYTNGGNGCNAAYGCNCARGGNAAYAARGAYGGNMGNAARGGNAARAARGGN AARAARGAYTTYAGYMGNAARGARAGYGGNGGNTCNGARATGGAYGCNTTYATHGAYNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGARCARNNNNNNNNNNNN GAYNNNNNNATHGCNAAYYTNCCNCARGCNGAYGGNAARAGYAARGTNAARAARAARAAR AARAARAARGCNAARAARTCNGCNGARCCNGAYGTNAAYTCNGCNGARAGYTCNYTNACN GARYTNAARATHTGYCCNAGYAAYGGNGTNGTNTCNNNNCCNCCNGTNGCNGARAARGAR YTNTCNGCNCCNACNGARGARTCNGTN---------------------------GCNGAR AARGARACNGARGTNGTNAARACNGARACNACNACNGTNCARAAYGGNACNGAYGTNCAR ATGGARAARTCNGTNCCNGAYGARATHCARGTNGARACNGTNGGNGAYGCNGARYTNTCN AAYACNAAYGAYYTNTAYGARGARAAYGGNGCNCCNAAR---------ATHGARGARGTN GARTCNAAR---------GCNGARGTNTTYGCNAARYTNAARAAR---AGYGGNGGNAAR YTNGTNTAYGAYMGNTCNTAYYTNATGGARYTNMGNGARTGYGCNTCNTCNCARACNAAR CCNGAYGGNYTNCCNAARYTNGARATHATHYTNGAYAARCCNAAYCCNTCNYTNTCNMGN CCNTCN---GCNGGNCCNGCNGAYTTYACNCCNGCNTTYTTYCARACNGCNGCNGGNAAY CARMGNCAYGCNCCNCCNATHGGNAARAGYAGYAGYMGNGGNMGNCARMGNCCNGGNGAR ATGCCNAAYATGCCNMGNGTNATHAARAGYYTNTCNATGTCNAGYGAYGCNAARTCNYTN CAYCARAGYGARAAYCCNTGGAARCARAARAAR------------AARGARGAYAARGAR GARAARACNYTNGARGGNGAYATHYTNTTYATHATGAAYMGNYTNACNCCNACNAAYTTY GARAARATGGCNGTNYTNATGAARAARYTNGAYGTNAARACNTAYGARGAYYTNCARYTN ATGGTNAARATHTTYTTYGARAARGCNACNATHGARACNAARTTYGTNGARGCNTAYGCN CARYTNTGYAARGTNATGTCNGGNYTNAARGTNCCNCCNCCN------CCNAGYGTNAAR GARCAYYTNGCNACNTTYMGNGTNGTNATGYTNACNAARTGYCARCARGARTTYGARGCN GAYAARACNATHATHTTYGARAAYCCNGAYGARAARAARAARAARYTNGARGCNGARTTY CCNGARGGNACNCCNGARMGNAAYGARAARATHGARAAYGTNYTNTAYCARATGAARYTN AARMGNATGAARTTYTAYGGNAAYGTNMGNTTYATHGGNGARYTNTTYAARYTNGGNYTN YTNACNGARAAYATHATGCAYGAYTGYATGTTYMGNYTNYTNAARGCNMGNGAYGAYGAY TCNYTNGTNTCNYTNAGYAAYYTNYTNACNACNGTNGGNMGNAAYYTNGAYACNGAYAAR GCNAARCCNMGNATGGAYCARTAYTTYCARCARATGTCNAARATHGCNGARGARMGNAAR ACNMGNATHAARTTYATHYTNAARGAYGTNATHGARYTNMGNCAYAAYCAYTGGGTNCCN MGNAARGARACNACNGGNCCNAARAARATHGAYGARGTNCAYAARGAYTTYGCNCARGAR CARGCNMGNAAYCARTAYYTNGCNAAYCARCCNCCNCCNCCNMGNAAYGAYAAY---CAR GCNGGNAGYMGNMGNGGNAGYMGNCARMGNCCNGAYGAR---AARCARAAYGAYGAYGGN TGGAAYACNGTNAGYTCN---AARGCNGTNMGNATGATHGAYGCNTCNAARATGAARTTY TCNAAR---AAYGTNATGGAYGARAAYATHCARYTNGGNCCNGGNGGNGGNGTNCAYMGN CARGCNYTNTGGGGNMGNGGNAGYCAYGGNGGNGCN---CARCCNTCNCARGARGARMGN CARAGY---GGNTCNAAYMGNTTYTCNGCNYTNACNAAYGAYGAYGCNMGNMGNTCNTTY CCNMGNTCNCCNTCNMGNGGNGARGGNTCNGCNGGNMGNGGNTAYMGNCARGGNCCNACN GCNGGNCAYGGNMGNGGNAARATHATGTCNMGNTCNAGYCARGARGGNGAYMGNMGNGAY YTNYTNTCNAAYAAYMGNTCNTTYATGGGNGGNMGNTCNCARAAYTCNAGYMGNGAYAAY AGYTGGAAYMGNGAYGARMGNMGNCARTAYYTNGGNCCNMGNAGYTCNGGNGARMGNGAY AAYCCNATGACNMGNAGYGAY---AGYGGNGTNCAYATGGARGARTTYMGNGCNCCNGCN GCNCCN------GCNGTNAARCARATGTCNGAYTCNGAYATHGARACNAARGCNTGYAAY ATHYTNGAYGARTAYYTNAGYATHMGNGAYYTNGGNGARGTNAARYTNTGYGTNAARGAR YTNGCNGGNCARAAYTCNATHCAYYTNATHGTNACNGCNAGYATHAAYAAYGTNYTNGAR AARAARGAYGARGCNMGNCARGTNACNGGNGAYYTNTTYCAYGTNYTNGTNAGYAGYAAY YTNYTNCCNGTNAAYATGTAYATHAARGGNYTNAAYGARGTNYTNCARTAYGCNAGYGAY ATGGTNGTNGAYATHCCNACNATGTGGAAYTGYYTNGCNCARGTNATHTGYCCNYTNYTN GTNGGNGGNTCNYTNCCNTGGTCNAARYTNAARCARGCNTTYACNCCNTAYYTNGAYAAY AARGAYGGNGCNAARYTNYTNGCNGCNATHATHTCNTAYTGYGTNGARAARCARGGNGAR AARGARGTNTCNCAYCARTGGCARAAYAGYGGNYTNAGYTGGTCNGCNTAYYTNAARTCN GAYGARATHAGYTCNTTYGTNTCNGAYAARAARYTNGARTTYACNYTNMGNGGNAAYTCN TCNCARTCNTCNGCNGAYGAYYTNGTN--------------------------------- GAYATHGARMGNATGATHMGNAGYMGNGCNAGYAAYGTNGARYTNATHTCNTAYATHGAR AARACNGTNTCNGGNAGYAARTCNGAYAAYAGYTTYATHMGNGCNYTNACNACNGCNGTN GTNAGYGCNTGYATHTCNGARTCNAAYAGY---------YTNAAYGARGAYGTNYTNMGN AAYCAYAARGAYGTNYTNCARAARTAYYTN---GGNAAYAAYGTNGAYYTNCARYTNCAR GCNYTNTAYGCNATHCARACNYTNATGGCNAARYTNGARCAYCCNTCNGGNYTNYTNTCN AARYTNTTYGARYTNTGYTAYYTNGARATHTCNGTNGARGARGAYGCNTTYTAYAARTGG GARAARTGYACNGAYCCNCARGARCARGARGCNAARGGNACNTGYYTNATGCARGTNMGN CARTTYTTYATHTGGYTNMGNGARAAYGARGARCCNGAR--------------------- ------------------------------------------------------------ ------------------------------------------------GAYGTNYTNAAY GAYYTNGAYGAYYTNTCNGAYCCNYTNGGNGAYGAYAGYATGGARGCNTTYATHAAYYTN GAYAARTTYYTNAAYGGNAAYTCNTTYTTYGAYGAR------GARGGNAAYYTNACN--- GTNGTNGARGARGCNGARGTNAARCCNGTNATHACNTTYGCNGCNCCNCARACNGGNATG YTNGARCARGTNCCNACNACNGTNACNTCNCCNCARACNTCN------AARCCNAGYGGN AARCCNTCNMGNAARMGNCCNGCNACNACNTCNMGNAARGGNGTNAARACNAGYYTNTTY GARATHCCNGCNGTN---------------TCNGTNYTNTCNACNGAR------GAYGTN TCN---GTNGAYAGYGARYTNGAYCAYGAYTAYAGYTCNAARMGNCARMGNATGGCNTCN CCNTCN------------------------GGNAAYAAYTCNAGYGGNACNATGAARYTN AAYACNATG------AAYGTNACNCAYAAYGTNTCNGTNCCNAGYACNAGYTCNGTNGAR GCNGGNYTNGTN---TTYGAYAAYTCNACNGAYAARCAYACNATHMGNMGNATHAARAAY AAYCAYGCNTCNAARMGNTCNMGNGARCARMGNAARCARAARTTYGTNGAYATGGAYACN GARGCNGARGAYYTNGTNGTNAARAAYCARCARYTNMGNGARCARATHGTNGARYTNGAR AARYTNGCNAARGARATGAARGARATHYTNGTNGCNAARATGGCNGGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGGCNGAYAGYGCNGTNGAYTCNACNAARGARGARGARGAYTGYGCNGAY TCNGTNGAYTCNAARGTNTCNTCNTCNTTYGGNGCNCARGCNMGNCARTAYTCN------ ------GAYTCNAAYTCNGGNCARGAYGGNAAYCARGARGTNAGYAGYTCNGAYATHAGY GARTCNGGNTGYYTNTCNTCNCARACNCCNMGNYTNCCNGGNCCNTCNGTNAGYTCNTAY AGYAAYGCNTTYTAYGGNAAYTCNCAYAAYGCNGGNATGTAYTCNAAYCCNTTYGTNCCN MGNGCNCCNTTYAARTCNGARGTNGTNTCNACNGAYCARTCNGGNTCNGARGTN---MGN GARAGYYTNATHGCNCCNAGYMGNYTNAAYGCNGCNGTNAAYAARGAYAGYTCNGARGCN GARAGY---GAYMGNAGYAGYTTYCCNAARTCNTCNATGYTNGCNCCNCCNAARYTNACN GGNGCNGTNTTYGGNGGNGCNAGYAAYMGNCAYGAYACNCCNAGYTCNACNTTYAAYTCN TAYAAYTCNTTYCAYATHMGNCCNTCNGTNTTYTCNGGNCCNTTYGARTCNCCNAGYAGY MGNGGNGCNGCNCCNYTNYTNAARCCNGCNAARYTNCCNGAYCCNACNAARTCNTGYGAY GGNAARGCNGAYTCNGCNAGYGARGCNGAR------GTN------CCNGGNGGNAAYGGN GCNAAYGCNTCNTCNGTNAGYGAYMGNYTNAGYGGNGCNGAYGGNGCNGTNGGNGGNAGY GARGTNTCNTCNTCNTCNTCNACNGCNGCNGCNCCNCCNCCNCCNCCNCCNAAYGTNCCN GAYGCNGAYGGNGCNGGNGGNGGNGARAGYACNCCNTAYAAYCARGAYATHGTNCCNGAY ATHAAYAARAAYAAYMGNYTNAARGAYTCNTCNGGNGTNTCNAGYAGYTCNCARTCNTTY GTNTTYGGNAARAAYATHTCNCARMGNGTNACNGGNGTNYTNTCNTCNTCNTCN---GAR AAYGARGCNTCNGCNTCNTCNGGNTTYGTNTTYGGNGARTCNYTNGGNTCNMGNGCNGTN GTNGARACNAAYGGNTCNACNCARGCNCAYAARGAYGARGARAGYGAYTCNGAYTCNGGN AAYAARYTNAAYMGNACNYTNGARGARTCNGCNMGNGARTAYCARGCNAARCAYGARATG MGNACNGARYTNGCNGARGTNGARACNATHACNGGNGARGARGARGARTCNAAYGTNYTN CARTTYAAYGCNAARYTNTTYTTYTTYGARACNCAYAAYGARTCNTGGGTNGARMGNGGN MGNGGNACNATHMGNYTNAAYGAYATGTCNGCNMGNGAYAAYACNAAYTTYCARTCNMGN YTNGTNATGMGNACNCARGGNAGYYTNMGNGTNGTNYTNAAYACNAARATHTGGCCNGGN ATGTCNYTNGARMGNGCNTCNCCNAARTCNATHMGNATHACNGCNATGGAYACNGAYGAR TCNATHAARATHTTYYTNATHACNACNACNACNAARGAYTCNGARAAYYTNYTNMGNGCN ATHGAYTGGMGNATHCARCARYTNAARATHCARGAYGARCCNGGNMGNCARCAYTCNGAY TCNMGNATHGGNGAYAARMGNAARGCNGAYGAYTCNGAYTTYGARYTNCCNYTNAARAGY AARAARGTNAAYAAYTCNCCNGAYCARGGNATHTCNATGACNAARAARGARGARTCNGAY AGYAGYGTNCARGAYCCNGARACNGARGCNTCNTGYGARAGYCAYTCNTCNTCNYTNACN ATHAARTCNGARTCNGAYTAYCARTGYATHCAYTGYGGNTTYTCNGCNGARAARYTNTAY CAYGAYTTYAARGCNGGNATHACNAARGTNGCNAAYTGYAARATHTGYGGNCAYGTNGTN GAYAARTAYATHGARTAYGAYCCNACNATHATHYTNYTNGAYGTNYTNYTNYTNCARAAR CCNGCNTAYATHCAYYTNYTNATHAAYGTNAARGTNAARTCNYTNTGGAARTCNTCNYTN YTNYTNYTNGTNGTNGARGCNTTYGTNAARYTNATHCARCARAARTCNGARYTNGGNGAY TTYTCNCARAAY---------GGNAAYATHTAYTCNTAYGTNGGNGTNGAYYTNTAYYTN AAYTAYYTNGTNGCNGCNGTNGARYTNATHAGYTTYYTNTTYTGYGTNYTNGCNGTNYTN ACNGTNMGNAGYGTNATHYTNTCNCARAGYTTYAARTAYGTNAAYACNTAYTTYATHACN AARGCNATHYTNYTNGCNAAYYTNGGNTCNGTNYTNGCNATGCCNGCNYTNYTNTGGGGN AARTCNTAYAGYCCNGTNYTNGTNTGGYTNGGNCARGCNTTYGTNTAYATGTCNGCNYTN CARGCNYTNMGNGCNGTNATH---CARGGNTCNCAYAARGCNGTNTTYGCNGCNATHGCN GTNGCNTGYGGNATGAGYGTNCARGCNGTNACNTCNGAYGCNTTYAGYCARTGG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GTNAAYATHGTNYTN GTNGARGGNGCNAAYYTNGTNCCNATGGAYGAYAAYGGNYTNAGYGAYCCNTAYGTNAAR TTYMGNYTNGGNTCNGARAARTGYMGNAGYAARCAYAARCCNAARACNYTNAAYCCNMGN TGGYTNGARCARTTYGAYYTNMGNYTNTAYGAYGARCARATGAGYCARYTNGARATHACN GTNTTYGAYCAYGAYACN------------------------------------------ ------------------------------------------------------------ ------------------------------------GGNTTYGCNGTNGTNTTYYTNGTN AARAAYGCNAAYGGNGGNMGNYTNGCNYTNAARMGNATGTAYGTNAAYAAYGAYAARGAY YTNGCNGTNTGYCARAARGARATHAARATHGCNAARGAYYTNAGYGGNCAYAARAAYATH ATHMGNTAYATHGARTCNAGYATHACNGTNACNCCNAAYMGNGTNTAYGARGTNYTNATH YTNATGCARTAYTGYMGNGGNTCNGTNATHAAYGCNATGAAYGAYMGNYTNTCNACNGGN TTYTCNGARCARGARATHATHAARATHTTYTGYGAYGTNTGYGARGCNGTNTCNMGNYTN CAYCAYTGYCARACNCCNATHATHCAYMGNGAYYTNAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGCNTCNTCN AARGTNTCNMGNACNYTNGTNAARTCNYTNCARGGNMGNTCNTTY---GCNGCNGCNGCN GCNGCNCARGCNGAYAARGCNTCNYTNGAYAGYAAYCCNAARTGYTCNGTNAARAARYTN AGYAAYGGNATGCAYGTNGGNGTNATHCCNTCNAAYTCNCCNGTNGCNMGNGTNGCNGTN GTNGCNAARGCNGGNTCNMGNTAYGARGAYGGNGAYAAYYTNGGNGTNTCNCAYTTYYTN MGNATGTCNTCNMGNYTNMGNTCNCARAAYATGTCNAGYYTNGCNATGACNMGNACNGCN CARCAYYTNGGNGGNGAYGTNACNATHATGGGNACNMGNGARTAYATHTAYTTYAARAGY GCNGTNACNMGNAAYTGYGCNGCNAARATGGTNCAYYTNYTNCARGARATGACNACNCAR CARACNTTYGCNCCNTGGGARGTNGCNGAYGTNCARAARGAYAARGAYGGNATGYTNYTN GAYYTNGCNGTNTAYCARACNMGNCCNCAYGTNMGNGCNGTNGARYTNYTNCAYTCNGCN GCNTTYMGNAAYACNYTNGGNAAYTCNYTNTAYGCNTCNGAYCAYATGGTNGGNACNTAY ACNMGNGARCARGCNYTNGARTTYACNAGYGCNAAYTTYAGYGTNGGNMGNATGGCNYTN ATHGGNATHGGNGTNGAYGARGCNGARYTNGARCARYTNGCNYTNCARTTYGARCCNGTN GCNTCNGAYGGNATGGCNGAYAARAGYTCNACNTTYCAY---GGNGGNGARATHMGNGAY GAYGCNGGNGGNGCNATHTCNTAYGTNGCNGCNGGNTAYTCNGGNCCNAGYYTNACNAGY AARGAYYTNYTNGCNGCNGARGTNYTNMGNCAYATHYTNGGNACNGGNCCNCAYATHAAR TAYAGYACNGGNACNGCNGTNTCNGGNYTNGCNAARGCNGCNGCNGCNGCNACNAAYGCN CCNTTYCAYGTNTCNGGNYTNAAYGCNACNTAYACNGAYAAYGGNYTNTTYGGNTTYACN GCNGTNGCNCAYTCNTCNCARATHGARAARGTNGTNACNGCNGCNGCNAAYCARTTYAAR GGNTTYGCNTCNGCNAAYGTNACNGAYGARGAYGTNTCNMGNGGNAARAAYAARYTNAAR GCNGARGTNTGYATGCARTTYGARAAYCCNGAYGTNYTNYTNAAYTGGYTNGGNGARCAR GCNYTNAGYGGNGGNGGNGTNGTNAGYCCNGARGAYATHTAYCARATGATHGAYGCNATH ACNGCNAAYGAYGTNAARATGGTNGCNAARAGYATHGTNAGYTCNAARCCNTCNATGGCN TCNACNGGNAAYACNAAYAAYGTNCCNTAYYTNGAYCARYTNATGGGNGGNAARAAYAGY AARCARAARGGNAARAARGGNAARAARGGNGARGARGARGCNAAYGARGAYGCNCCNCAR GARCARCARAAYGARGTNGGNGGNGAYGGNGARGGNGARCARACNAARAARGTNGARGAR AAYGGNAAYGCNGCNAARYTNGARACNGGNGARGAYGAYAARGGNGAYGCNAARGCNGAR GAR---------------------CCNCCNGCNGAYGCNGCNGCNTCNGARTCNACNGAR GCNGCNAARGARGARGAYACNAARCCNGCNGARGARTCNGCNCCNGCNGCNAGYGARGAR GCN------------------------CCNGCNGCNCCNGCNGCNGCNGCNCCNAARGAR GARGAR------GCNGCNCCNGCNCCNGCNGARGARCCNGCNCCNGTNGARGCNCCNGTN GCNGCNCCNGTNGARACNCCNGCNGARGTNCCN------------------------GCN CCNGTNGARGCNCCNGCNCCNGTNGARGARAGYAARCCNGARGARGCN---CCNGCNGCN GARGARCCNCCNAARGARGARGCNGCN--------------------------------- CCNGTNGARGARCARCARCCNGARGCNCCNGCNCCNGARCCNGARGCNGTNGARGARAAR CCNGCNGARGARACNCCNGCNCCNGCNGARCAR--------------------------- ------------------------------------------------------------ ------AAYCCNCCNTCNGCNAGYGAYGARAGYTCNCCNGCNAARACNTCNGARTCNGCN GARACNGGNGCNGCN---------GAYGGNTCNGCNGCNGARACNGGNGARACNGCNGCN CCNAGYGARGARTCNACNCCNGCNACNGTNMGNACNGARTTYAARTGGGARAAYGGNGGN GARACNGTNYTNGTNAGYGGNACNTTYAAYAGYTGGCARGARAAYGTNGCNYTNTCNAAR GARGGNGARATHTTYTCNGGNTTYYTNGAYYTNCCNGTNGGNGARTAYYTNTGYAARTTY ATGGTNGAYGARCARTGGGTNGTNAAYAARGAYYTNCCNGTNMGNTCNGCNGARGAYGGN CARGARAAYAAYGTNATHYTNGTN------------------------------------ ------------------------------------------------------------ ------------------------TCNTCNGTNATHGGNTGYTTYYTNTGGGAYYTNGCN YTNGTNTGYYTNTTYATHGGNCARCAYTCNYTNATGGCNACNGCNTGGTTYAARGARCAR YTNTCNTCNTGGYTNATHGTNACNGTNTCNGARMGNYTNATHTAYATHGGNGCNACNTGY ATHTCNYTNATGGTNYTNATHYTNCARTGGCARTCNATHCCNGAYGTNTAYYTNTGGTTY ATHGAYACNCARCAYMGNCAYTTYYTNTGGACNTTYTTYYTNYTNTGYCAYATHGTNGGN TGGYTNGTNATHGGNYTNGARGTNGTNYTNATGGAYGTNGGNGARYTNYTNGGNYTNACN CARGTNTAYCAYTAYAAYGGNYTNGTNCARCCNCAR---YTNGGNAARAARGGNGCNAAR YTNMGNGARYTNTAYTCNMGNATGMGNCAYCCNGGNGTNGTNGTNYTNACNGTNYTNYTN TGGYTNCAYCCNYTNATGACNYTNGAYMGNGTNYTNYTNGCNTCNATHYTNACNTCNTAY ATGGTNTGGMGNCAYAGYTTYGARGAYGCNCAYTGYMGNTTYGCNGARAARCAYTTYTAY TCNGARGCNACNMGNMGNAARTCNGTNMGNTCNGTNMGNTAYGARTAYGTN--------- ------------------ACNGAYYTNTCNYTNTCNTAYGAYGAYGGNCARATGAAYGTN GCNYTNYTNATHACNACNATHACNGGNAAYCARTGGTAYGTNYTNYTNGARACNMGNACN TCNGARTCNAGYTTYTCNCCNGGNTCNGAYYTNAGYGARATGGGNTAYGAYCAYATHGAY GGNMGNAGYATHCCNCCNMGNACNATHYTNGAYTCNGTNGARGARAAYACNATHATHTTY ACNCCNMGNCARTTYCARACNTTYCARCCNCCNACNYTNYTNAARCCNCAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CCNATGCAYGCNACNATH CCNCAYTTYTGGAARATGGTNTGGGARCAYAARAGYAARGTNATHGTNATGYTNTCNGAY YTNATGGARAAYAARYTNAARGTNAAYYTNTAYTGGCCNGARAAYYTNAAYGARCCNATH AGYTAYGGNGAYGTNGTNGTNGARATGACNAAYTTYTCNCARYTNAAYAARTAYATHATH MGNAAYTTYAARATHTCNATHGGNACNMGNACNMGNMGNGTNACNCAYTTYTTYATHCCN GGNTGGTGGGAYTTYAGYGCNAAYYTNACNTTYGAYGAYGTNYTNGARTTYGCNCARYTN GTNMGNAARGARACNACN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GCNAGYYTNMGNCAYATGTCNCAYAAYMGNGARACNCCN ATGGTNGGNAGYGGNGARGGNTCNTCNATGACNYTNGAYMGNTCNTAYMGNCARACNMGN MGNCCNAARGAYTCNTGYAAYTCNGCNCCNGGNACNYTNCARMGNCARCAYMGN------ ---------------------------------------------AAYMGNTAYTCNGAY CARCCNACNCCNCCNCCNCCNCCNGCNTAYAGYATGCAYTCNAGYGAY------------ ------------------------------------------------------------ ------------------------------------AAYCARGARCAYCARTCNATHMGN ATHYTNTCNGTNGCNGGNGCNGTNTCNGGNATHAAYTCNCCNTCNAARGCN---AAYTTY ATHATHGCNTCNACNMGNGAYTCNCCNYTNAARTCNCARACNTTYGTNYTNAAYACNGCN AAYGGNATHATHACNCCNAGYCAYAAYATHACNACNGTNTCNCARAGYCARGTNYTNGCN TCNCCNCARYTNTCNCCNTCNCARGCNTCNCCNGTNYTNYTNGGNMGNYTNCARACN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------CARGARAAYAAYACNAAYTAYCARMGNGGNYTNCCNGARGGNACNGAYCCNYTN TAYAAYYTNGTNACNAAYTCNAARACNACNYTNATGCAYCARGCNGTNTCNACNAAYCCN TTYAAYAGYAARTAYTTYATHTGGYTNGAYGGNGGNTAYGGNCAYGGNGAYCCNAAYYTN TAYCCNTCNGAYGGNGTNTGGCAYCCNAARCAYYTNYTNTCNCAYCCNGAYCARGTNACN TTYATHGCNTTYGARAGYYTNGGNGCNGAYMGNGARGARGTNMGNACNYTNTAYAARAAR AARACNGCNTGGATGGCNGGNGGNYTNTTYGCNGGNGGNAGYGGNGCNATGGARMGNYTN TAYTAYYTNCAYAARCARATGATGAAYGARTAYATGGCNMGNGGNACNATHGAYGAYGAY CARACNACNTTYGTNGAYTGYGTNATGMGNGAYCCNAARAAYTTYMGNCCNGTNAARGGN AGYTGGTAYGAYYTNATGAARCCN------------------------------------ ------------------------------------------------------TAYYTN AARGGNCARYTNGARGAYTAYATHCARCARTTYGGNAARACNGTNAARYTNTAYMGNAAY GARAARMGNGARGGNYTNATHMGNACNMGNTCNMGNGGNGCNGARYTNGCNACNGGNGAY GTNATHGTNTTYYTNGAYGCNCAYTGYGARTGYAAYMGNAAYTGGYTNYTNCCNYTNYTN GARCCNATHMGNCARAAYMGNACNACNATGACNGTNCCNATHGTNGAYGGNATHGAYTGG AAYACNATGGCNTAYCAYCCNGTNTAYGGNGCN---TAYAAYMGNGGNATHTTYGARTGG GGNTTYYTNTAYAARGARAARGAYGTNCCNCARMGNGARYTNGAYAARMGNCARCAYACN AGYGARCCNTAYAAYTCNCCNACNCAYGCNGGNGGNYTNTTYGCNATGGAYMGNAARTAY TTYATGGARYTNGGNGGNTAYGAYCCNGGNYTNATGATHTGGGGNGGNGARAAYTAYGAR YTNTCNTTYAARATHTGGCARTGYGGNGGNMGNATHGTNTGGGTNCCNTGYTCNCAYGTN GGNCAYATHTAYMGNYTNMGNGGNTAYCCNATHGGNAAYATHTTYMGNTGGTTYATGGAY AAYGTNGCNTAYGAYGTNTAYGGNGCNTCNGAYTGYCAYCARCARGGNCAYAAYCARGAR TTYMGNYTNAAYATGAARGGNCARATHGGNTAYGGNGARMGNTGYATHYTNGCNCARAAY GCNAAYACNYTNCAYGTNAGYTAYTGYGCNATHGARCCNTCNGGNCCNTGGGARTGGGAY GARGTNACNGGNYTNATHCARCAYMGNGAYYTNAARMGNTGYGTNAARGTNGGNTCNGAY ATGATGYTNCAYYTNGARTTYTGYAAYAARCARGAYGARGARATGCARTGGGTNATHAAY GCNGTNTTYCCNTGGAARTGGMGNACNAARGCNATGCARYTNGARAARGTNATHAARACN YTNTCNAAYCAYTGYGTNMGNGTNGTNGARAARCAYGARGARYTNYTNGAYAARTTYCAR AARAAYCARGARCARTAYGTNAARYTNCARTCNAARTTYCARGARAARGGNGAYCARATH AARAARGCNMGNGARGTNYTNATHCCNGTNTCNACNGARYTNMGNACNYTNMGNGARAAR TAYGARATHGCNGTNMGNTGYCARATGGARGCNGARTCNTAYGCNGTNAARNNNAARAAR AARTAYAARGTNYTNAARMGNCARAGYCARATGYTNGGNGCNAARTTYGGNAAYATGAGY TCNGTNGARATHGAYATHGAYGGNACNGARGAYGARGAYAAYGCNGARAARGARTAYATH GARAARYTNGAYCARCARATHGAYGARYTNGARGARCARAARAGYACNYTNGCNGTNAAR GTNAARGARATHATGGARAAYTTYGAYATHGARAARGARGCNAAYGGNYTNYTNMGNGCN AARATHGARCARATGAARGARGARYTNAARCARTCNAARGARACNATHAARGARCARGAR GAYYTNYTNCARCARGTNGCNAAYACNTCNGARAARGCNTAYAARGARTAYGTNCAYATG GARCARACNTGYCARAARGARAARGTNGTNMGNAAYGARGCNGARMGNTTYGCNCARAAR YTNTCNACNGARMGNGAYCARGCNMGNMGNGARAGYACNYTNGCNYTNAGYAARGTNTCN GAYAAYAARAARYTNATGGAYGCNYTNYTNGARATHCARGARYTNAAYGGNAARGCNGCN CARGTNAARGARGARTAYGAYGTNAARATHAGYCARYTNGARGARCARYTNAAYGCNGCN AARGARGTNTAYACNGCNGAYGGNYTNCARACNGAYAAYGARGARYTNCARGARGARYTN AAYTCNTCNCARGARAARYTNGARAARAGYGARGCNGARATHAARCARATGMGNGARAAR TAYGAYGGNYTNATGGCNACNTAYAARACNYTNGARGARAARTAYGAYGCNGCNATHGCN GCNCCNCCNCCNCCNYTNCCNCCNCCNCCNCCNCCNYTNCCNGCNATHAARACNGGNGGN TTYYTNCARMGNATHGTNGGNMGNAARGGNCARMGNGARMGNGCNAARGARAARYTNAAR AARGGNGGNGTNAGYACNAAYGAYAAYCAYACNAARGCNGTNGAYGARATGATGGCNMGN ATHAARAGYGGNAAYGTNGGNYTNAARCCNGTNYTNAARAARCARACN---------CAR TCNYTNCCNGARMGNGARGAYCARAGYGCNATGACNGARYTNCARGGNYTNYTNACNAAR ATGAARAARGCNMGNAGYGARGAYGAYYTNGCNACNTTY---GARGARACNGGNGTNGAY GARCARTCNGARYTNGGNAARATHYTNAARAAR---MGNCARAARGCNATHAARGARACN GAYCCNCCNTCNGCNAAYAGYAAY------------------GGN--------------- ------MGNCCNGTNCCNMGNCCNMGNAARYTNTCNGTNATHGCNGAY------------ ---------------------------------------------TTYACNAAYGCNGTN GGNMGNYTNMGNGAYGARACNGAYATHGAYTTYGGNTAYYTNATHGTNGAYGAYTGYGAY AAYTCNGTNMGNGCNTCNAARYTNATHYTNGAYYTNATGGGNCAYGAYYTNAARATHGTN GAYCCNATHACNACNYTNACNTTYMGNCCNGARGAYGCNTGGGTNGTNGTNGGNGCNACN AGYAGYCCNACNACNACNGCNATGYTNTCNCARATGACNGARYTNAAYMGNCCNYTNATH TCNTTYAGYGCNGCNTCNYTNAGYYTNGAYAAYAAYAARGTNTTYCCNTAYTTYGTNMGN GCNYTNGCNGAYGAYGCNYTNCARATHCARGCNATGYTNGARATHGTNAAYGGNATGAAR GCNTCNCAYATHGCNGTNTTYGTNCARGAYACNGTNTTYGGNYTNGARYTNTAYTCNYTN TTYMGNAARGARGCNGARAARGARYTNATHTGYGTNGARAAYGTNTTYAARYTNCAYGAY TAYACNCAYGARGAYGAYATHAARACNGAYYTNTTYYTNYTNGGNGCNAAYAARGTNCAR GTNATHGTNYTNTTYGTNGGNCCNACNATHATHACNAARGTNYTN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GAYMGNGAYCARGGNMGNGARMGNGARATHCCNTGGGGNMGNGARMGNYTNGAYMGN GAYMGNGAYMGNGAYMGNGAYMGNGAYMGNGAYMGNGAYMGNGAYGAYTGGGAYMGNGAY MGNGAYMGNMGNTTYGAYMGNMGNAAYGAYMGNTTYMGNMGNGAYAGYGAYMGNGARTAY GGN------GGNAAYMGNAAYMGNGAYMGNMGNGAYMGNCCNTAYGAYMGNTCNGGNMGN MGNMGN---ATGGARGAYGARAARGARCCNGARTGGTTYACNGGNGGNCCNACNAGYCAR AAYGAYACNATHGARYTNMGNGGNTTYGARAGYGARAGYCARAARMGNCCNAAYGGNYTN MGNYTNAARAARGCNGARYTNGARGGNGARMGNGARMGNCCNGCNMGNGGNAARATHGAR TCNGTNTCNGARGARGAYCCNGARGARGAYAARAARTCNAAYGAYGAYGAYGTNTTYGTN AGYAGYMGNAARGARCAYAARCARCARGGNGGNGARCAYCAYCARTTYGARCCNCARCAR AAYTAYCCNAAYCCNGCNGGNGTNTCNAAYTTYGAYYTNGAYGARTTYYTNAARACNAAY YTNCCNYTNAAYGARGAYGCNGARACNCARGGNAGYMGNTTYTCNMGNTTYTTY------ MGNGGNCCNGCNCCNAAYACNCARTCNGARGAYYTNATGCCNAARGAYYTNYTNGAYGAY GGNMGNGGNAGYCCNGTNGTNCCNTCNCCNGARYTNGARMGNGAYCCNCCNTAYTCNAGY GGNGCNACNATHCCNAAYTCNGCNGGNGAYAAYAAYGCNTCNYTNCCNCCNTCNGTNACN GCNYTNTTYAAYMGNGCNNNNNNNNNNNNNTCNTCNNNNNNNNNNATGTCNAGYAAYAGY AGYTTYAGYACNCARGAYGCNGARGCNCARYTNAARGCNATGYTNTTYGGNGGNCAYMGN GAYTCNGCNTCNTCNAGYGGNACNGCNTCNCCNGCNGGNGTNCCNCCNAAYTTYCARMGN MGNGTNAARACNGTNGCNGARYTNGARGCNGAYATGCAYCARAGYTCNCCNCARAARMGN GAYAGYCCNGTNGTNATHGGNAAYGTNGCNGCNCCNACNACNGAYATGACNGCNTTYAAY AARTTYYTNATHATGATHAAYGCNGCNTCNGARGCNAAYCARAAYGCNACNMGNAARGAR GGNCCNCCNYTNTCNGAR---GGNTAYGGNACNGTNCCNAGYCAYAGYGARTTYTCNCAR GCNYTNATHMGNAAYAARGARCAYCARATGCARYTNYTNCAYYTNTCNATG--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNMGNGCN TCNACNATGTCNTCNAAYCARACNCARGAYATGGARGARGCNTCNTCNCCNAGYYTNMGN TCNACNTCNAGYTCNGTNGTNTCNAAYGTNAGYGAYACNTAYCCNGARYTNAGYGCNAAR MGNAAYGCNGARAAYMGNMGNTCNCARCAYAGYCCNGGNATGMGNCARAARCCNAARMGN GTNTCNACNCCN---------------------ACNAAYACNGCNGARGARTCNGCNTTY YTNATHGAYACNATGCARAGY---TTYCCNTTYCAYMGNAGYTAYGGNAAYTAYATHCCN CARACNGTNTTYYTNGARACNGCNACNTGYYTNTAYTCNCCNCAYAAYATHCAYACNGCN CARGTNYTNCCNGGNGTNACNATHYTNTTYYTNGCNCARGCNCCNMGNCAYCCNYTNGCN GAYCCNYTNTAYCARGTNATGAGYAAYATHCARGAYYTNAGYTTYGGNMGNMGNGTNAAR YTNCCNMGNTCNMGNAGYATHCAYGTNTAYGAYATHATHAAYTCNYTNYTNGCNAARYTN CAYAAYAGYYTNMGNAARTTYAARGGNMGNGARMGNAGYYTNATHTCNGAYATHCAYGCN MGNTGGGARAARGARGAYYTNAARCAYAARYTNYTNGARTAYYTNGARMGNGAYTCNMGN TTYCAYATHCCNCCNGARGTNGARGCNCCNYTNAGYGARATGAAYAARAARYTNMGNGAR YTNTTYTCNYTNYTNTTYYTNTAYCCNCCNCCNGARAAYCCNCARYTNTGGGARTCNYTN TCNCARYTNMGNGTNGCNATHAAYGCNGARYTNYTNGAYTAYMGNGARTAYYTNAAYGTN AARTCNCARMGNAAYATHACNATGACNAGYTAYTTYGARAARTAYCCNGGNYTNGTNTAY TTYATHTTYGTNGAYMGNMGNYTNCAYCARATGACNGCNCCNTCNYTNAAYATHTCNYTN AAYGARGGNGARGARGARAAYGCNAGYACNTAYYTNAARGAYAAYATHTGGMGNATGTAY CARGTNATGATGCARAARYTNACNGARGGNTAYACNACNGTNGTNYTNMGNGARGGNGAY TTYTAYTAYTCNCAYTTYYTNTGGTTYGARGAYAAYGCNGGNAAYCCNYTNGCNATHCAR GARTGYTTYAARCCNTCNAAYAARTAYGCNTAYCCNGGNATHYTNTGYGGNTCNTTYTAY AARGAYATHATHCARCARTGYTTYCCNCAYATGYTNGCNAAYTCNGTNTTYTGYTTYGAR ATGTTYATGATGCAYGTNGGNAGYGTNCARCCNCARTAYATHGCNTCNCAYTGYAARAAR YTNGCNAAYGARYTNTGGGARATGTCN------------------------------GAR AARYTNCCNGARACNAGYGGNYTNTCNTTYMGNGAYATHTAYCCNTAYYTNACNGARGAR GAYYTNGAYATGGARAARMGNTAYGCNCAYATHMGNGAYGGNGGNCAYTTYCARGAYACN CARAGYTCNTTYGTNACNCCNCARAARAARTAYAAYMGNCCNTTYMGN------------ ---------------CCNATHYTNCCNACNMGNTCN------------------------ ------------------------------------------TCNCCNMGNACNAARYTN TCNAAYCCNMGNATGGTNCCNAGYCCNTCNTCNTCNTCNAARGTNGCNATGGARGTNAAR CARACNGGNAGYACNATHAGYCARMGNAARMGNCCNGCNTCNTCNYTNACNCCNGAYGCN ---GARYTNCCNMGNCCNGCNAAR------------------------------------ ---------------------------------CAYAARMGNATHAGYATHTCNCAYACN YTNACNGTNTCNTCNACNCCNGTNAGYGARGGNGAYATGACNACNATHGCNTCNACNTCN AGYGARMGNATGTAYAARMGNGTNCCNTTYACN--------------------------- ------------------ACNGTNYTNGARTCNGARCAY---------GGN--------- GTNMGNMGNTCNCCNMGNAARYTNTCNACNACNAARGARTCNGAYATGAARCCNAARGAY CCNGAYACNMGNCARATGGARTCNACNGTNAGYAGYGAYGGN------------------ ------------------------------------------------AARATGAARMGN TCNGARMGNCAYATGATGMGNYTNAARMGNATHATHGCNCAYGTNYTNAARGARAARGGN GTNGARTAYGGNAAYCCNATHCAYGARGCNTGYTCNAARAAYYTNYTNAAYGTNAGYATH GTNYTNYTNAARACNYTNCCNAAYTCNAARAAYYTNACNAAYGARATGAARTCNGTNGTN TTYGARCARGTNCARCARATHATHAAYYTNGARAARMGNMGNTCNGGNATHTCNYTNAAY TCNTTYGCNTAYCCNACNATGAARGAYMGNATHCCNGTNATHYTNTCNAARATHGTNGAY TAYYTNAAYMGNCAYMGNGARGCNYTNGTNCARGARTTYAAYGGNGAYGGNTCNGAYGAR GARYTNAARACNATHATHGGNGCNATGTCNTGYYTNMGNTAYCARGTNATGACNAAYAAR GCNGCNGARCCNYTNAARGAYTCNGCNAGYGAYGCNATHGTNTGGAAYCARGAYYTNGAR ACNGARYTNTAYGGNGGNGARGCNCCNAARTGGTTYAAYAAYCCNTGGYTNTGGATGGAR TGYTAYATGTAYMGNAARATHCARGARGCNGTNATGATGAGYTCNTGYTTYAARTCNYTN GAYGTNTTYGGNCAYCARAARAAYGAYGCNTTYAAYAGYTCNTTYGGNTCNATHTCNCAR YTNACNATGCAYYTNAAYGARGTNACNAGYCARATHTCNYTNTGGGGNAAYAARTGYGAY YTNTCNATHTCNTCNGGNGARGARAAYAAYCARACNYTNAAYCCNGTNCAYCARYTNGAR AGYYTNAARTCNAAYATHYTNGTNGAYGAYACNGAYGCNATHYTNCARYTNYTNCAYCAR AARCARGTNGAYCCNGAYAAYAARGGNGCNAARGTNTCNATHGTNYTNGAYAAYGCNGGN TTYGARTTYATGACNGAYYTNTGYYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNYTNTGYACNACNTCNGCNAGYMGNAAYYTN TCNACNCAYTCNGCNGAYCAYAGYTTYATGGTNTAYMGNAAYGARMGNTTYGTNAAYATH CCNATGACNGTNAARAAYYTNGGNGAYACNTCNMGNGTNGAYTAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TCNMGNAARNNNNNNNNNAARAAR MGNAGYMGNAGYAARGARMGNAARMGNTCNMGNAGY---------------------AAR GAYMGNAARTCNMGNAGYMGNAGYMGNGAYMGNAARMGNMGNGAYGAYMGNGAYAARGGN GGNAGYMGNMGNGGNMGN------------------------MGNAGYMGNAGYMGNAGY MGNGAYMGNGGNGARMGNMGNAARMGNAGYAGYMGNTCNCCNMGNMGNMGNTAYAGYAAR AGYCCNATHMGN---GARMGNTCNCCNGARYTNACNGTNGARGARMGNGAYGTNMGNACN ATHTTYTGYATGCARYTNTCNGCNMGNATHMGNCCNMGNGAYYTNGARGARTTYTTYTCN TCNGTNGGNAARGTNMGNGAYGTNMGNYTNATHACNGAYAAYAARACNMGNMGNTCNAAR GGNATHGCNTAYGTNGARTTYGCNGAYCCNGARTCNGTNACNYTNGCNATGGGNYTNACN GGNCARAARYTNYTNGGNGTNCCNATHYTNGTNCARCARTCNCARGCNGARAARAAYMGN GCNCARCCNGCNGTN---CCNGCNCARGCNCARAARCCNGCNTCNGARGGNCCNYTNMGN YTNTAYGTNGGNTCNYTNCAYTTYAAYATHACNGARGAYATGYTNMGNGGNATHTTYGAR CCNTTYGGNAARATHGTNGAYATHAARATHATGMGNGAYCAYGAYACNCARMGNTCNYTN GGNTTYGGNTTYATHAGYTTYGCNAAYGCNGAYGAYGCNAARAARGCNYTNGAYCARYTN AAYGGNTTYGARYTNGCNGGNMGNCCNATGAARGTNGGNCAYGTNACNGARMGNTCNGCN GAYGGNGGNCARGGN------GCNCARAAYGGNGTNGGNGGNCARYTNGAYACNGAYGAR ATGGAYMGNGCNGGNATHGAYYTNGGNGCNACNGGNMGNYTNCARYTNATGGCNAARYTN GCNGARGGNACNGGNTTYCARATHCCNCARTAYGCNGCNAGYGCNYTNAAYATGTCNGGN CCNGCNCCNGTNACNGGNYTNCCNGCNCCNAAYAAYYTNGGNATGGCNCCNACNYTNCCN ---------------------ATHGCNGCNGCNGCNATHCARCCNCCNACNCCNGCNGCN CCNGCNATH------GCNCCNCCNATHGCNACNCARTGYTTYATGYTNTCNAAYATGTTY GAYCCNACNTCNGARACNMGNYTNACNTGGGAYCARGARGTNMGNGAYGAYGTNATHGAY GARTGYAAYAARCAYGGNGGNGTNYTNCAYATHTAYGTNGAYAARAAYTCNCCNCARGGN AAYGTNTAYGTNAARTGYCCNAGYATHTCNGCNGCNGTNGCNTCNGTNAAYTCNYTNCAY GGNMGNTAYTTYGCNGGNMGNATGATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TCNTCN GTNAGYGTNCCNTGYCCNACNTGYMGNACNAAYTTYATHGCNACNGAYGAYAGYATHACN AARYTNCCNGCNGAYCAYMGNGTNGTNCARYTNATGGAYTTYGTNAARCAYACNGARMGN TCNACNATHTCNTAYTGYTCNAARCAYAAYATGCARCCNYTNAAYTTYTTYTGYGARCCN TGYGTNMGNCCNGTNTGYMGNGAYTGYACNTTYYTNGAYCAYAARGAYGGNCAYGGNCAY YTNGTNATGAAYYTNGAYGARGCNATGGAYAARTAYGGNCCNGTNYTNGAYACNGCNATH GCNGARATGGAYACNGARGCNGCNAARGTNGARGAYAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNGAYTCNYTNATHTCNACNAAYGCNAGYCARTAYGCNTCNACNATGTCNYTNGCNCAR TCNACNTCNAARTCNTCNGCNACNTCNATHATHGGN---GGNACNMGNAARCCNMGNATG CAYGCNMGNYTNAGYAARACNACN---------YTNTTYMGNACNTCNTCNCCNAAYAAR ACNCARTCNCCNACNTCNACNCARGARTCNCAYYTNATHGARGCNGTNGCNGAYGCNCAR ACNAGYCCNMGNGTNAARGGNYTNACNAARGAY--------------------------- AGYAAR------MGNMGNCARAGYGAYGCNYTNACNCCNATHMGNGARATGACNAGYGAR GAYGARGARGARGAYATHGGNAARAARTTYTCNCARGTNTCNATGAGYCARATHMGNGAY ACNMGNTCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATHCCNGARGCNGARAARATHYTNCCNYTNGAYGARATHTCNGARGARGARAARAARGTN CAYGCNGAYTTYTTYGAYGGNMGNCCNCCNAARACNCCNGARMGNTAYYTNAARATHMGN AAYTAYATHACNGAYTGYTGGATHAARTGYAARCCNGCNTTYYTNAAYAARACNTCNGTN MGNCCNGGNYTNAARAAYTGYGGNGAYGTNAAYTGYATHGGNMGNATHCAYGCNTAYYTN GARTGYATHGGNGCNATHAAYTTYGGNTGYGAYCARGCNGCNTAYMGNAAYCCNCAYAAR ATHATHAAYGGNGGNYTNAAYAGYMGNGCNAARGGNATGAAYAARGAR------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TAYATGGARTCNTGYGGNGCNCAYAARGCNGGN GTNGCNAARATHGTNCCNCCNAARGARTGGGTNCCNMGNMGNGCNGGNTAYGAYGAYATH GAYYTNATGATHCCNGCNCCNATHGARCARGTNGTNACNGGNCARCARGGNYTNTAYACN CARTAYAAYGTNCARAARAARCCNATGCAYGTNAARGARTTYGARGCNYTNACNAAYTCN CCNAARTAYMGNACNCCNAAYCAYTTYGAYTAYGAYGAYYTNGARMGNAARTAYTGG--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------YTNGGNACNTCNAARGAYATHACNYTNGGNCCNACNGCNATHATGTCNYTNATG ACNGCNGCNTTYGCN------TCNCCNGTNAARGAYGAYCCNACNTAYGCNATHGTNYTN TGYYTNATGACNGGNYTNATHCARTTYGTNATGGGNGTNTTYCAYYTNGGNTTYYTNGTN MGNTTYATHTCNCAYCCNGTNATHAGYGGNTTYACNTCNGCNGCNGCNATHACNATHGCN GTNGGNCARYTNAARTAYGTNYTNGGNYTNCARAAYATHTCNMGNGARTTYYTNCAYATG GTNTAYGAYYTNTGYGTNCAYATHCCNGARGCNATGCCNACNTCNGARGTNCARCARYTN YTNGAYGAYCAYAARTCNYTNATHTAYGAYGAYCARACNGAYAARGTNAARTGYAAYYTN ACNAAYCAYGARATGCCNGCNAARGTNGGNGCNATHGARAGYTAYYTNAGYGGNAARAAR TAYAARMGNYTNGCNGARYTNGARGCNTAYACNTAYGARGARCAYAARACNCAYATHGTN CCN---AAYAARMGNAARCCNGARATHGARATGTTYTGYMGNYTNACNYTNMGNCAYYTN GARAARACNCCNAARGCNATHCARMGNCAYATHAAYGGNATHAARTTYAARAAYGCNYTN AARMGNTGGAARGARTGYCARAARACNGGNACNAARTTYGTNCCNMGNMGNTCNAARMGN CCNGARGAYGARTCNGARGARATHAARGAYGAYGTNTCNAGYGAYGARTGYYTNATHGAY GAYGGNGGNTTYGAYGAYGAYGAYGAYGARGAYTTYAGYGAYYTNTAYCCNGARAARGAY TTYAAR---------------------GAYACNGCNGAYGAYGAYGAYAAYGAYAAYATG GAYGAYAAYGARGARGARGARAARGAYGAYAAYGTNAARAGYGARAAYGTNCCNCCNGCN ACNGGNAARAAYAARAARATHAARAAYAARAARAARAAR--------------------- ---------CCNYTNCCNCCNGGNACNATGGGNTGGCCNATHGTNGGNGARACNYTNGCN YTNYTNMGNAARGGNATHAAYTTYTAYGCNGARAARACNAGYCARTAYGGNAAYATHTTY AARTCNCAYYTNYTNGGNAGYCCNACNGTNMGNGTNNNNGGNGCNGANAAYGTNMGNTCN YTNGTNNNNAARGARCCNGAYCARYTNNNNNNNAARTGGCCNNNNNNNGTNNNNNNNYTN YTNGGNNNNNNNAGYYTNNNNNNNNNNNNNGGNCCNGANCANCCNNNNYTNNNNMGNCAY YTNGARAARGGNTTYACNCCNNNNMGNYTNNNNNNNTAYTTYCCNNNNGTNNNNCARNNN NNNNNNGANNNNYTNCARCARTGGYTNGARMGNGGNGARGCNGGNGARCARGTNATHGGN TTYGCNNNNTGYGARGAYYTNACNGCNGAYATHATHYTNGARGTNGTNYTNGGNTGYMGN AARGARGAYGAYNNNGAYNNNAARGTNMGNNNNGCNYTNAARGAYNNNAAYNNNAAYYTN NNNAGYYTNCCNNNNAARATHCCNNNNNNNGGNTTYNNNAARGCNYTNNNNGCNMGNNNN NNNATHNNNCARTTYGTNGARNNNMGNATGTCNNNNNNNNNNAGYGAYNNNGAYNNNNNN AGYYTNATGGAYNNNYTNYTNTCNNNNCAYGGNGGNGARNNNNNNNNNGARGARGAYGAR AARNNNNNNGAYAAYGCNNNNGGNNNNNNNATNGCNGGNTCNNNNAGYACNTCNNNNGCN YTNNNNTGYYTNYTNNNNYTNYTNNNNAARNNNCCNGAYGTNYTNGARAARGTNMGNGAR GARYTNACNTCNGCNGGNATHGCNGCNTCNGAYAGYGAYGCNGARYTNNNNNNNAGYNNN YTNCARAARYTNGARTAYGTNNNNTGYGTNGTNAARGARNNNYTNMGNNNNYTNCCNCCN GTNNNNNNNNNNNNNMGNNNNNNNNNNAAYNNNNNNGANNNNNNNGARTAYMGNNNNCCN AARGAYTGGACNNNNNNNNNNAGYATHMGNGANACNCAYNNNYTNACNTCNNNNYTNYTN CCNNNNGGNGAYNNNTTYAAYCCNTCNMGNTGGCARNNNNNNNNNGGNNNNACNNNNNNN NNNNNNNNNNNNCCNTGYAAYTAYATHCCNTTYGGNTCNGGNCCNMGNATGTGYYTNGGN MGNCAYYTNGCNCAYATGATHYTNCARGTNTTYATHGTNGARGTNGCNMGNAAYGCNAAY TGGACNGTNGTNAAYCCNGAYTGYGAYATGGAYTAYACNCCNGTNACNAARCCNAARGAY GAYYTNCCNYTNACNTTY---GTNYTNTCNGCNTTYMGNAAYYTNCAYMGNGCNMGNMGN GARGTNTTYGCNGGNGAYGARMGNGCNYTNAAYGARGTNMGNGARAARATHAAYACNGGN TTYMGNGARAARYTNGARGARACNGAYCCNGCNAARATHGAYGARTCNYTNATHYTNGCN AARGAYGTNGCNTAYYTNYTNMGNTCNACNGTNGTNCARYTNCARGARAAR---AGYGAY AGYGAYACNTAYAGYYTNMGNATHACNAARAAYACNATHYTNCCNAARAAYACNCCNTTY GAYCCNACNAARGARATHCCNGCNAARCCNMGNMGNAARAARTGYTCNGAYAAYGCNGAR ACNACNAAYTCNMGNTTYYTNGTNAARGCNAARGARATGMGNGARTTYTTYAARYTNACN GARGAYCCNGTNATHAGYGARTTYYTNAARATGGAYAGYTGYAARMGNATHGCNGAYAAR TAYYTNATHGCNATGGTNTTYGCNTAYTTYAARMGNGCNGAYTTYTCNATHAARGAYTAY AAYAGYACNAAYTTYTTYACNGGNYTNTAYYTNGCNAGYGAYGTNGARGARGAYGARGAR GARATHAARCAYGARATHTTYCCNTGGGCNYTNGGNAARAAYTGGMGNGARACNTAYGTN GAYTTYYTNAARAARMGNGAYGARYTNTTYAARMGNATHGAYTAYAARGCNATHATHAGY MGNAARTGYTGYGAYGARATHATGAAYATHATHCCNGAYAGYCCNYTNTGGAARMGNGAR MGNTCNYTNCAYCAYGCNGGNGCNATHMGNGGNTAYGCNAARGAYCCNMGNGAYGAYGAY ATGCCNMGNGGNCCNGAYGCNAGYCCNYTNYTNTGYCCNGARTGYGAYACNCCNGAYAGY CARTAYGGNTCNGCNAGYCCNGAYAAYYTNAGYTGGATHATHTCNTCNGGNGAYTCNTCN AAYAAYAGYGTNTTYYTNCARTGYYTNGAYTGGYTNAARTCNGAYYTNGAYACNYTNCAR ACNYTNGGNAGYYTNGCNATHGGNAAYTTYGCNMGNMGNGAYGCNTAYTGYGTNGARYTN GTNGAYAAYGGNATHGTNGGNAARYTNATHCCNYTNYTNAARTCNGGNCCNGAYACNTCN TTYTAYYTNCARCAYGCNGTNYTNAGYACNYTNMGNAAYYTNGCNATHCCNGCNGCNAAY AARCCNMGNYTNCARGARCARGGNGTNATGGAYGCNTGYYTNTGYYTNATHAAYTCNGAR GTNATGGCNGTNGTNTTYAARYTNYTNGGNYTNYTNMGNATGYTNATHGARGGNCARGAR TCNGCNGCNATHMGNYTNGGNCARGARMGNGCNTTYYTNGAYTGYYTNTGYGARTGGTGY ACNGTNGARGTNCAYGCNGGNGTNAARGGNGARGCNCCNMGNGTNATHGCNTCNYTNATH AARAAYAGYMGNACNYTNGCNGTNATHCARAAYYTNGTNMGNGCNAAYTGYGTNGGNCCN YTNGTNGCNATGGCNCARTCNGARCAYYTNGTNATGCARAAYGARGCNGTNATGGCNYTN ACNTTYATHTGYAGYATGGCNYTNGGNGAYGCNGCNGTNGCNYTNAARGARGCNAAYYTN GCNGARGTNGTNTGYAARYTNYTNAARGARGARAARATGCCNGTNGARATGMGNGAYAGY CAYMGNATGTTYYTNCARAGYTTYATGTCNMGNGGNGTNATGAAYACNGGNGARGTNAAR GCNTCNTAYATHCARTCNAARAARMGNTTYTCNGARCARTTYATGGARGAYAAYATHATG GCNCARATHCCNGAY---------------TTYGTNMGNACNATHAAYATGGCNATHTCN TCNTTYAAYYTNGARATHMGNAARGGNATHCARGARCAYGAYGGNTCNAGYGTNTAYTGY YTNGTNAAYACNGTNGARAGYGCNATHTCNMGNYTNTCNTCNACNTAYACNCARAAYGAR YTNGARYTNTTYAARAARGTNGTNGARTAYATHGTNGARTCNGAYGAYGGNAARATHGGN TCNMGNATHGCNYTNAAYYTNACNGARAAYYTNGGNAARMGNATGGGNATGGARGARGCN CARAAYYTNTTYAAYMGNTTYGARCARGARAAYTGGATHATHAARGGNGGNGAYGGNAAR ATHTCNYTNTCNGCNMGNACNATGYTNGARYTNGAYCARTTYYTNCARGAYGTNTAYCCN GCNYTNATHAARAARTGYAAYYTNTGYAAYAARATHTGYYTNCARAGYGARAARTGYTCN AGYTGYGARGTNAARYTNCAYTAYAARTGYTCNCARAAYYTNTTYTCNAARCARCCNGAR AARMGN---TGYCCNAGY------TGYMGNGARYTNTGG---------GAYATHGARATH CARGGNTAYCARMGNTCNGARGCNAGYAGYGTNTAYMGNCARTTYGTNMGNYTNTCNTTY CARYTNAARGTNTCNTGYTTYGAYAARGAYTAYATHGTNACNATHAARTCNYTNCCNTTY CAYATHYTNTCNGGNTCNYTNCARCARYTNGARGCNATHGGNACNCARATGTGGTAYTGY AGYAAYAAYGGNAAYATGTAYGAYGAYTGYAARYTNTAYGAYGARYTNCCNAARGARGAY YTNTGYMGNATHYTNGAYCARMGNATHCARAGYATHAGYTCNGAYGCNMGNCARYTNTCN GAYGAYGCNAARAARTCNTTYYTNAARATGYTNAAYGTNAARGARGAYAAYYTNATHTCN YTNTAYTCNTTYGTNAARGGNGAY------GCNAARCCNGARGARAARAGYGGNGARGAR AARMGNCCNACNTTYTTYTCNTGGTTYTAYGCNGCNGTNAAYACNATHGARAARGAYYTN YTNGTNCCNTGGAARGARGGNGTNGTNTAYGAYTTYYTNAAYCAYGARGARGCNCARCAR ATHYTNYTNAGYGAYGAYATHCCNGTNCARACNGCNYTNATHMGNTCNTCNGTNYTNAAR CCNAAYAGYCAYCARGAYGCNAARGTNAARATHGCNYTNGARATGAARATHCARACNGGN GAYAAYGTNGAY------GTNAAYGGNATHYTNYTNGAYGGNGAYTTYATHACNAARAAY GGNYTNTAYAAYACNYTNAARTCNATHTGYAAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TGYYTNTCNGCNATH YTNGARTGYTAYAARGARTCNGAYTGGCCNTCNGTNGCNGCNTGYYTNTGYMGNCARYTN GGNGCNATHCCNGAYCAYCAYCAYAGYGCNGTNTAYYTNGCNAGYYTNGTNCCNYTNAGY GCNMGNGGNAAYCAYYTNCARGTNMGNYTNAGYTTYYTNYTNYTNTGYYTNGTNYTNGAR CCNGARMGNMGNGAYYTNATGGCNGTNTGYYTNGAYAARGTNTCNCCNYTNACNATHGGN MGNYTNGGNTGYGARYTNMGNGARGARTCNGAY---TCNMGNYTNGCNTCNTGYYTNGCN MGNYTNATHAARGAYGAYGTNTAYAARGTNAAYTCNACNYTNGTNYTNYTNGAYMGNGCN YTNGGNGAYGARYTNAAYMGNTGYCARCARCCNAARGARGARYTNAAYTTYYTNACNAAY CARGTNAARATGGTNATHMGNGARATHMGNGAYAGYATHAAYTCNYTNGAYYTNTCNAAR YTNAARGAYAARATGACNATHATGACNGTNAARTGGATGACNATGTCNGTNCCNCARACN AARMGNGTNCARMGNAGYYTNTTYCAYTGGGCNACNTCNACNTCNCAY------------ ---------------------------------------------------ATGAGYGGN MGNAAYAARAARGTNMGNGTNTGGGGNMGNYTNMGNCCNACNTCNAAYTAYGCNYTNGAR AAYATHGARTGYATGCCNGAYAAYAARGGNATHAAYATHCAYATGAARMGNGAYCCNAAR AARGGNGTNGTNAAYAAYCARATHYTNGAYTGGTCNTTYAARYTNGAYGGNATHTTYAAY AAYGCNGAYCARGARGTNGTNTAYAAYACNGTNGCNTCNGAYGTNGTNGGNGGNTCNYTN GAYGGNTAYAAYGGNACNYTNATGTGYTAYGGNCARACNGGNGCNGGNAARACNTTYTCN ATHACNGGNGCNACNGARAGYTAYMGNCAYMGNGGNYTNATHCCNMGNGGNATHTCNCAR YTNTTYMGNCARATHGARGAYMGNYTNGARTAYAGYATHACNGTNMGNGTNTCNTAYATG GARATHTAYAAYGARCARATGTTYGAYYTNYTNGGNTCNTTYCCNGARTCNAAYTGGAAY AAR------AARGAYGTNAAYTCNAGYCCNGAYCCNATGGTNATHTCNGARAAYCARGGN GGNGTNTTYGTNAARGGNYTNTCNTGYCAYYTNGCNCARAGYGARGARGARGCNYTNAAY YTNYTNTTYGARGGNGARACNAAYMGNTCNATHGCNGCNCAYTCNYTNAAYMGNCARTCN TCNMGNTCNCAYTGYATHTTYACNGTNTAYYTNGARTCNMGNTCNMGNATHCARTCNAAY GCNAARTAYACNGTNTCNAARATHAAYTTYGTNGAYYTNGCNGGNTCNGARMGNYTNAGY AARACNAARTCNGARGGNAARATGAARGARGARGCNATGTAYATHAAYAARTCNYTNTCN TTYYTNGARCARGTNGTNATHGCNYTNGCNTCNAARACNMGNGAYCAYGTNCCNTTYMGN CARTCNAARYTNACNCAYTTYYTNAARGAYTCNATHGGNGGNAAYTGYAAYACNGTNYTN ATHGCNAAYATGTGGGCNGARAARAAYCARYTNGARGARACNGTNTCNACNYTNMGNTTY GCNACNMGNATGATGTGYGTNAAYAGYGARCCNGCNGTNAAYGARATHTAYGAYCCNGCN YTNYTNGTNAARAARYTNCARMGNGARATHTCNCAYYTNAARTCNGARYTNGCNATGCAY GAYACNYTNACNAAYMGNAGYATGGTNTCNTAYGAYCCNYTNTCNGARCARCARAARTAY GARATHMGNACNCARGTNMGNMGNTAYYTNGARGGNAGYYTNGAYGARATHGAYATHGTN AAYATHMGNCARATHGTNGGNTCNTTYGARACNTTYMGNGARYTNTAYCARGAYATGGAR AARGARATGGARGCNAARYTNMGNGARAARTTYATGYTNATHGAYAARACNGAYCCNGCN TCNATHGCNGCNGCNCARCARAARYTNACNGARYTNGARGARATGTTYYTNGAYGCNAAR GARGARGCNGGNATHCCNATHGCNGAYGAYGGNACNTAYGTNGGNGARYTNGARGGNGGN AGYTTYGGNATHGGNACNGCNCCNAARAGYGCNAARGGNGAYTCNTCNGCNGTNGTNCAR YTNAARMGNAARGARMGNGARMGNGAYMGNAARMGNGGNTCNMGNGGNGCNAGYAGYCCN ATHGCNGGNAARTCNGTNTCNAGYCCNTCNCARAGYATHAARGGNGARMGNAARGCNGAR TCNCCNCCNACNCCNATHGGNGARMGNGTNGARAARGARCARCARGAY------GGNTCN GCNTCNCCNGTNAGYTCNACNGGNAAYYTNTCNMGNGCNGARMGNAGYCARMGNCCNAGY AARGCNCAYAGYAARCARAGYTTYCAYGAYATHGCNGARYTNMGNCCNGAYACNCCNCCN ACNMGNAGYGCNGCNTTYGARGARTTYAARAGYGAYMGNGGNAGYGARATHAAYMGNATH YTNATHGARAAYAARGARTGYYTNTCNACNGCNAARAARACNTAYTCNGARYTNGCNAAR CARATGAAYTCNYTNAARGTNAAYATHGAYACNTCNMGNCAYMGNYTNGAYGARYTNAAR GTNYTNMGNGARGCNGARGGNCCNATHYTNAAYGARGAYGGNGAYATHGTNATHAGYGAR GARGARTTYCARGARATHACNAAYYTNMGNGARYTNAARATHTCNTAYMGNACNAARMGN GAYGARYTNGCNAARACNGARTCNGARGTNAARTAYTGYCARAARYTNGTNGAYCARTGY MGNYTNAARYTNATHCARGARTTYGAYAAYTGGTAYAGYGARAGYTTYYTNAGYAAYTCN GANGAYCAYCARACNAGYYTNGGNGTNGGNACNGGNGTNMGNCCNGGNGTNATGYTNCCN ATHACNAGYYTNGCNAAYGARGAYGARCARGARAARTTYGARMGNYTNCARYTNGARYTN ATGATGAAYAAYCCNGARTCNGCNGCNTTYTAYAAYGCNCARATGMGNACNTCNMGNMGN AARATHTAYGGNGCNGCNYTNACNCARGCNCARCCNGCNTTYCARMGNCARCCNGGNACN CCNACNATGAGYTTYMGNAAYCARCCNCCNGGNMGNATGCARGTNCARTAY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------TTYCCNATH------TAYGTNGTNGAY GCNTTYACNCAYAARCCNYTNAGYGGNAAYCCNGCNGCNATHTGYYTNGTNCCNTCNGAY GTNACNGTNTCNGAYGAYGARATGCARAARATHGGNGCNGARATGAAYYTNTCNGARACN GCNTTY------ATHGARTGYYTNAAYAARGAYTTYGTNTCNGGNCARCARTTYTCNYTN MGNTGGTTYACNCCNACNACNGARGTNAAYYTNTGYGGNCAYGCNACNYTNGCNTCNGCN GCNGTNYTNYTNGAYGAYGTNGGNAAYAARAAYAAYGTNGTNGARTTYACNACNAARAGY GGNAARYTNTCNGTNATGMGNCAYGCNGAYAARGCNGGNTTYYTNGCNATGGAYTTYCCN AARAAYGARCCNGCNCCNYTNGARTCNCARCARYTNGARAARYTNYTNYTNACNATHGTN GARGAYYTNGAYTGGGTNCARGARGTNCARTAYTCN---AAYACNACNAARAARYTNGTN GTNMGNYTNAARGAYAGYATHNNNMGNAAYGTNYTNGARGGNYTNMGNCCNCARGCNAGY GTNATGATGGCNGCNGARCCNTCNGGNATGGTNAARGGNGTNGGNYTNACNYTNAARGGN TGYMGNGAYAAYGGNTGYGTNGAYGARGCNGGNGARGCNTAYGAYTTYGTNTCNMGNTAY TTYGCNCCNTGGYTNGGNATHCCNGARGAYCCNGTNACNGGNTCNTGGCAYACNGTNGTN GGNGCNTAYTGGGCNAARGARYTNGGNAARAAYCARYTNTAYGCNMGNCARTGYTCNCCN MGNGGNGGNGAYYTNYTNGTNGARGTNAARGAYTCNMGNGTNACNYTNATGGGNCARGCN GTNATHAAYYTNAARGGNACNTTYMGNYTNATGGGNAAYAAYCCNAARAARCARTCNAAR TCNTTYAARGTNYTNCARTGGATGACNGARACNGARAARGAYGARGARGGNGARGARGAR GARCARGARGAY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CAYTTYCCNAARGGNGGNCARGAYGGNCAYYTNCCN AARYTNATHGARAARTGYYTNCARAARTAYCARACNGGNGARCARTAYGCNAAYGAYCCN MGNTTYATHAARYTNTGGATHATGTTYTCNAAYTTYGCNGARTCNCCNACNGAYGTNTAY GCNTAYATGTTYGAYAAYGGNATHGGNGTNACNGTNTCNYTNYTNTAYGTNGARTGGGCN ACNATGYTNGARATHGCNGGNAAYACNAARMGNGCNGAYAGYATHTAYGCNGARGGNATH AAYMGNYTNGCNGARCCNMGNGAYYTNYTNGTNCARAARCARCARCARTTYCARAGYMGN YTNGCNAARAAYATHACNYTNCARGTNGGNGGNGCNCCNAAYCCNGARACNGAYATGGAR CARGAYGARAARMGNGARGTNYTNAAYMGNYTNAARCCNACNGGNGCNGGNCAYAARGTN GGNACNATGMGNGTNGGNGCNGTNAGYYTNGGNTCNGCNGGNAARYTNAARGAYCARMGN GGNGCNGCNCCNMGNCARGTNCCNTCNAARGGNTTYACNATHTTYACNGAYGARAAYAAY CCNCARCARCCNCARCARACNAARGARTGGAARTCNATGCCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GAYAARGARTAYYTNTGYATHYTNGCNTCNGAYTCNTCNGAYCARGAYYTNACNCCN TAYTTYCCNCARGTNAAYAARTTYATHCAYAARGCNMGNATGGARGGNGGNGTNGTNYTN GTNCAYTGYYTNGCNGGNGTNTCNMGNAGYGTNACNGTNACNGCNTCNTAYATHATGTCN GTNACNGARYTNGGNTGGMGNGAYGCNYTNAAYTCNATHMGNGGNGCNMGNAGYGTNGCN AAYCCNAAYTAYGGNTTYCARAARCARYTNCARAAYTTYGAYAAYGARCARGTNGTNGAR GARMGNAARMGNYTNAAR------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARGCNATHAAYTGYGCNGGN TAYGARTGYATGAARAARYTNATHTTYAGYYTNMGNGAYCARYTNATGAAYAARATGGGN CAY---------TTYYTNCCNAARYTNGCNYTNTCNCCNATHGAYTCNGAYMGNMGNACN GCNGTNACNGGNGAYGARGCNTTYTTYGARTTYTCNYTNMGNTGYGAYGGNYTNTCNGTN GGNCCNATHGGNGARGARCCNAAYACNATGGTNGTNATHAGYTCNGTN---TCNCCNCAR GAYGAYTCNTGYCARGARYTNACNMGNACNGARATHGARYTNAARACNTGYAGYCCNGTN TTYATGAARACNYTNTGYTTYAGYAGYGCN---CARATHTCNACNGAYACNCCNATHAAR YTNGARGCNMGNGAYATGAAYGARGGNGTNATHMGNMGNGARYTNGGNTCNGCNTTYTTY ACNATGATGTCNYTNACNTCNTCNCCNGGNAGYACNYTNCARTGYTCNYTNGGNGAYGGN AAYGGNACNATHACNATHACNGCNTGGCARGAYGAYTCNGARTCNGAYTCNGGNAGYATG CARTCNGCNGARCARACNYTNGTNAGYCCNGCNCARTCNMGNACNCAYACNMGNGAYCAY GTNAARCARYTNTCNGTNTGGTTYGGNGAYATHYTNACNMGNGCNTAYMGNTTYCCNGCN ACNAAYGGNGCNGARATHAARGTNCAYGARTTYYTNGGNGARAGYAARYTNACNTAYTAY YTNCCNCARAARYTNYTNACNATHTTYGCNAAYGARGAYAARYTNATGYTNCARMGNYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNTGGCCNGCNGCNCARGTNGARATHTTY GGNAGYTTYAARACNGGNYTNTTYYTNCCNACNAGYGAYATHGAYYTNGTNGTNTTYGGN AAYTGGGARTCNYTNCCNYTNMGNACNYTNGARAARGCNGTNYTNGAYAARGGNATHGCN GARCCNTCNGAYATHAARGTNYTNGAYAARGCNTCNGTNCCNATHGTNAARYTNACNGAY AARAARACNGARGTNAARGTNGARACNAARTAYTGYGCNAAYTGYAARMGNGAYATHGCN GCNGCNAAYTTYGTNATGCAYGARGTNCAYTGYMGNMGNAAYATHGTNYTNTGYAARAAR TGY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNAARTCNGARCAYGTNGGNGTNGARGAR YTNTCNMGNGCNAARTGGATHTGYYTNAAYAARATHTCNTAYAARGAYCCNAARGGNACN YTNMGNATHTGGGARGGNGTNTCNMGNACNACNAARAGYGCNGGNGARGCNGAYGCNGTN GGNATGATHTCNATHTTYCAYGAYCCNATHACNGAYYTNAARAGYGTNATHYTNATHMGN CARTAYMGNCCNCCNATGGARACNTAYACNATHGARTTYCCNGCNGGNYTNATHGAYGCN AARGARACNGCNAGYGAYGCNGCNGTNMGNGARATGAARGARGARACNGGNTAYGAYGTN GCNGTNGTNGAYGTNTCNCCNGCNACNTCNYTNGAYCCNGGNGTNGGNAGYACNACNYTN AARYTNGTNACNTGYAARGTNGAYACNTCNAGYYTNAGYAARACNGARMGNCCNAARCCN ACNGGNGGNGAYGCNGAYGARTTYGTNCARGTNGTNGTNGTNCCNATGAAYAARYTNATG CCNAARYTNAARGARTTYGCNGCNGARGGNGAYTGYGTNGAYTCNMGNGTNTAYGCNTGG GCNGTNTCNYTNGGNMGNAARCCNGGNCARAARGAYGGNCCNATHTTYYTNATGYTNTGY TCNGTNAARAAYMGNAAYGGNGAYAARTAYYTNYTNTAYAARAAYGTNGARAAYATHTTY TCNAARTTYYTNAARGARGGNAARGCNACNATHMGNYTNTCNGARCCNCCNAGYGAYATH GCNTTYAGYAARGCNGAYCCNTCNCARYTNAAYATGTTYYTNAARYTNGCNMGNTAYGCN TGYGAYGGNAARGAYYTNCCNGAYAARATGYTNAGYATHYTNGCNCCNGTNTCNYTNAAR CARGTNGARAARCCNGTNACNAGYYTNGTNGTNTCNAARCCNTCNGARTAYCCNATGGCN ATHCCNAARTCNYTNGAYAARYTNACNGTNAAYAGYTGYYTNYTNMGNMGNGTNAGYCCN CARATHYTNTCNYTNGCNGGNYTNAARGARYTNGAYYTNAGYTAYAAYCARATHACNACN YTNCCNGAYGCNTTYGCNGAYYTNGCNAAYYTNAARATHYTNAAYYTNMGNTCNAAYAAR YTNTCNTCNTTYCCNAGYGCNYTNYTNTCNGGNMGNYTNCARACNACNYTNTTYYTNYTN GAYYTNMGNGARAAYGARATHGAYMGNYTNCCNGCNGAYATHGTNAARYTNAARTCNYTN YTNACNYTNAAYYTNAGYCAYAAYCARYTNAARTTYYTNCCNGARTGYYTNGGNYTNATG ACNTGYYTNYTNAAYYTNAAYATGGCNAAYAAYAGYYTNGAYTTYYTNCCNGGNAGYYTN YTNTCNMGNATGTAYGARACNGTNGAYTTYAGYGAYAAYCCNTTY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AGYTCNAGYMGNAGYACNMGNCAY MGNAGYAARAARGAYAARGAYAAR------------GAYMGNGGNAARMGNGAYMGNCAY AGY---AGYAGYCAYCAYCAYMGNAARAARAARMGNMGNMGNMGNGARCCNAGYGCNAGY AGYAGYAAYAGYAGYGARGAYTCNTCNTAYMGNCAYAARCAYCAYCAYMGNAGYAARMGN AARAARMGNGAYMGNMGNTCNMGNTCNCCNAGYYTNGARGTNYTNGGNCAYTCNGAR--- ------------------GGNGGNGGNCARCAYGCNCARGTNGTNGARGCNAGYCCNCCN CCNTCNCAYGCNAARACNGARGGNGAYGARGGNCCNYTNAGYCAYGARGCNACNCCNCCN CCNCCNCCNCCNCCNCCNCCNTCNTCNGGNTCNGARCAYGARGGNGARMGNGARGCNGAR CARATGGGNGGNAARAARAARGARGARGARGARAAYGGNGGNGGNTCNGCNGAYATHGAY GGNGARGARATGGARGARGARGGNGARGAR------GARGARGGNGGNCARGARGARGAR GTNAAYACNGCNGTNATHATHAARCCNCCNCARATHATHGTNCCNTCNTAYGTNGCNGCN ATGAAYCARCCNCARYTNTAYACNACNCAYCARYTN---GGNGCNGCNCCNACNAAYACN ACNACNGGNGARACNACNACNACNACNTCNTCNGCNACNGCNATGGAYACNGAYGGNGAY AARGGNGGNAARAARMGNAARAARGAYAARCCNGGNAARGARAARGCNACNTCNTCNACN AGYAGYYTNATGATGAARAARAARMGNGTNTCNTCNATGGTNCARAARTGGCARCARGTN AARGCNGARGTNGARAARGARGAYMGNGCNAARGARYTNMGNCARGCNGCNATHMGNGAR AARATHAAYCARYTNAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------TAY AGYMGNGGNGARATHMGNAGYGTNYTNTCNATGATHGAYGGNGGNAAYAARAGYAARAAR CARGGNAAYAAYATHACNGGNYTNTCNAARAAYATHTCNGCNTTYGGNATHGCNGGNTTY GTNMGNTTYYTNGARGGNTAYTAYATGATHYTNATHACNAARMGNAARAARGCNGCNATG ATHGGNCAYCAYACNGTNTAYAARATHGARGAYACNTCNATGYTNTAYGTNCCNAAYGAY GCNGTNMGNAAYGTNCAYCCNGAYGARAGYMGNTAYGTNAARATGTTYCARAAYGTNGAY YTNTCNAGYAAYTTYTAYTTYAGYGGNACNMGNTTYYTNAARMGNGGNTCNAAYYTNGAR GGNTAYGTNGCNAAYGARATHGARACNGARCARATHGTNCARGAYACNGCNGTNACNTTY YTNGAYMGNGGNAARGTNTCNTCNTTYGTNCARYTNMGNGGNTCNGTNCCNYTNTTYTGG TCNCARGAYATHTCNAARATGGTNCCNAARCCNCCNATHTCNYTNGAYCARMGNGAYCCN TAYTGYAGYGCNGCNGGNATGCAYTTYAAYMGNYTNYTNTAYMGNTAYGGNTCNCCNATH ATHGTNTTYAAYYTNGTNAARACNMGNGARAARAARMGNCAYGARAGYATHYTNAGYGAR GAYTTYGTNAAYACNATGGAYTAYYTNAAYCARTTYYTNCCNGCNGARCAYAARATGCAR TAYATHGGNTTYGAYATGGCNMGNGTNAAYAARMGNAARGAYGCNGAYGTNATGYTNMGN YTNAAYMGNATHGCNMGNTAYTGYYTNMGNMGNACNGGNTTYTAYYTNCAYGTNCCNCAR CCNCARGCNCARTGYYTNYTNAARGAYTGYGARYTNCARAGYYTNAARGGNGTNTGGGGN TCNAAYGGNATGTTYCARACNGGNGCNGTNMGNACNAAYTGYGTNGAYTGYYTNGAYMGN ACNAAYACNGCNCARTTYGCNATGGGNMGNAGYGCNYTNGCNTAYCARYTNTAYGCNATG GGNATGATGGARMGNCCNCARYTNGARTTYGAYACNGAYTGYGTNAARYTNYTNGARGAR YTNTAYGARGAYCAYGGNGAYACNYTNGCNYTNCARTAYGGNGGNAGYCARYTNGTNCAY MGNATHAARACNTAYMGNAARATHTCNCCNTGGACNTCNCAYAGYMGNGAYATHATGCAR ACNYTNTCNMGNTAYTAYAGYAAYGCNTTYTCNGAYYTNGARAARCARCARGCNTTYAAY YTNTTYYTNGGNGTNTAYATHCCNAARGARGGNGARGCNAAYYTNTGGGAYYTNCCNACN GAYTAYTAYYTNCAYAAYAARCCNTCNYTNGGNYTNCCNACNCCNMGNCARAAYTAYTGY CARTGGTGGGARTCNGARGTNTGGGARACNYTNCCNATHCCNMGNGAYGARGTNAAYAAR CCNAAYATHGTNCAYACNGCNGTNYTNACNGCNCCNCARMGNGAYGARCAYGTNAAYTCN TTYTAYGARCAYTAYMGNCCNGARGARYTNTCNGTNTTYGAYGARATGTAYCARATGTAY YTNTCNCARGCNTGYTGGAARCAYYTNCCNAARCAYTCNAAYGARTTYAGYCCNTTYTGY GTNMGNCAYGTNGTNGARACNAAYGARCCNAAYCCNATGYTNCCNGGNAARGAYTCNTCN TCNTCNACNACNTCNTTYGGNTCNGARGGNAARAARGTNCCNCCNGGNATHGAYATHTTY CCNATHTCNGCNTTYAARYTNGAYAGYACNTTYTAYGTNGARCCNCCNCCNGTNAGYMGN CARGCNAARGAYATHTAYACNGCNTAYGTNAAYMGNGGNCAYCARGGNGCNCARGCNGTN TCNGAYGARAAYMGNAAYGCNTAYATHMGNTAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TCNATGGCNGARTCNGAYAAYYTNYTNCAYATGCARAARTCNYTNCARAAYYTNYTNGCN GGNYTNACNGCNAGYCCNGARAAYAARACNGARGARGARATHGAYGTNTCNAARGGNGCN YTNCCNYTNACNCAYGTNGAYGCNAAYAARTGGTTYTAYMGNGAYCCNCARAAYCARATH CARGGNCCNTTYGAYAGYGARAGYATGGCNGARTGGTTYMGNATHGGNTAYTTYACNATG AAYYTNATHGTNAARMGNGGNTGYGAYGAYTCNTTYAARCCNYTNGGNGARYTNATHAAR CARTAYGGNMGNGTNCCNTTYGTNCCNGGNCCNCCNYTNCCNCCNYTNATHACNAGYACN GCNGCNGTNCCNGGNATHCCNGGNATHCCNGTNYTN------CCNCCNACNATGATGCCN TCNYTNGTNACNCCNATGATGCCNGGNGCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GGNMGNACNTCN MGNTCNTCNGAYGGNMGNGARACNCCNATGATGGCNGCNTCNCCNGAYMGNATHYTNMGN GCNTTYGARGTNACNGAYGARATHGARGCNGCNAAYGAYCARYTNAAYGTNAAYAARTTY GAYGARGTNTGYGCNCAYYTNMGNTCNACNYTNGARAARGARATHAAYCARYTNTTYGGN GAYATHGARTTYYTNCARAAYTGYYTNGAYAAYGARGCNGAYATHMGNGAYTGYGTNGAY ACNCCNMGNGTNTCNMGNGARCCNACNYTNACNGARYTNMGNGARGARMGNGCNTCNYTN GARAARGARYTNYTN--------------------------------------------- ------------------------------------------------------------ ---------------------------------------------GCNACNGARATHTGY AAYAARGCNAAYGARGARTAYGTNGARGARAAYTAYCARMGNGCNYTNGAYYTNTAYACN GARGCNYTNACNYTNGAYGAYAARMGNGAYGAYATHCAYTGYYTNMGNGCNCARGCNCAY ATHTCNYTNGGNAARAAYTCNGCNGCNATHCARGAYTAYGAYGARGCNATHMGNATHAAY GARAARAAYCARAARGCNTAYATHAARAARGGNTGYYTNYTNYTNAARATGGAYGAYGTN YTNCARGCNCARATHGTNTTYAARGCNGGNCARAARCAYTGYGARAARGARGGNGAYTTY CARGAYTGGYTNGAYAARGTNGARATHMGNATG--------------------------- ---------------------------GARATGTCNAARGARCCNCCNACNYTNAARTAY AAYTGGTAYCARACNCAYACNCAYGTNGTNYTNACNYTNYTNGARAARAAYGTNAARAAR GARGAYYTNACNYTNAAYGTNGARGGNMGNTCNGTNCARATHTCNGTNCARAAR---GAR GGNYTNGCNAAYGAYYTNAAYATHATHYTNGCNCAYCCNATHGTNTCNGARGARACNCAR TCNAARYTNTTYTCNACNAARATHGARYTNAARTTYAARAARATGGARGGNATHCARTGG YTNCAYYTNGARGGNTCNCCNGAYGARAARAAR---GAYGTNYTNCCNTCNTGYGCNGCN CCN---CCNATGGCNGARCCNCCNAARTAYCCNAGYTCNTCNCAYGCNCCNMGNGAYTGG GAYAARYTNGCNGCNGARGTNGCNGARGARGARAARAAYGARAARYTNGARGGNGAYGCN GCNYTNAAYCARTTYTTYCARAARATHTAYGCNGAYGCNTCNGAYGAYACNAARAARGCN ATGATGAARTCNTTYTCNGARTCNGGNGGNACNGTNYTNAGYACNAAYTGGGAYGARGTN GGNTCNAARAARACNGAYGTNAARCCNCCNGAYGGNATGGARTAYAARAARTAYGAR--- ------ATGCCNAARMGNAARGCNGCNGAYGCNGAYGCNGGNGAYTCNCCNAGYGAYGCN AARGCNGTNGCNGGNGAYGCNCCNAGYGARGCNAARAARCCNGCNATHGCN--------- AGYAGYGTNMGNGGNMGNGGNMGNCCNCCNYTNTCNGAYGARGARAARGCNAARMGNGCN GCNGTNAARAARCCNTCNTCNGGNMGNGGNMGNGGNMGNCCNAARGGNTCNACN---AAY ACNCCNAARMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AARYTNYTNAGYGTNAARACNCCNATHGTNGARGCNGAYMGNATHMGNACNYTNGCNTGY AARGCNYTNGCNGGNATGTCNMGNTCNGARACNATHMGNCARATHATHGGNAARMGNCCN CCNYTNAAYAAYGGNCARYTNCARTCNYTNGTNAARGARCCNGTNYTNGCNGAYAARMGN GTNGTNCAYYTNCARTTYTGYAARTTYGCNTCNATHYTNYTNGARAARATHGCNGGNAAR GAYACNAAYGTNYTNGGNGCNACNACNYTNCARGARATHMGNMGNGCNGGNGTNGTNGCN CARACNYTNATHGTNTAYCARGAYAARGARYTNYTNCARYTNATHCAYGARCAYYTNAAY TCNAARGGNYTNTAYGAYACNGCNACNGCNYTNCARAARGARGCNGGNYTNCCNAARTGY TCNACNCCNCCN------CCNTCNCCNAGYACNCCNAARGCNMGNMGNCARYTNAGYCAY CCNTCNACNCCNGCNTTYTCNAGYATGAGYCCNTCNYTNCCNCCNGCNCARTAYCAYGGN CCNACNTCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------MGNACNCCNCCNAARTAYCARYTNATHGCNCCNAARACNTCNCCN TCNCCNAARTCNGCN---TAYATHCCNYTNCCNMGNATHAGYCCNAARMGNAARGARYTN AAYMGNCARGTNMGNCAYATHYTNCCNAARTCNTTYGTNTTYGARACNAARAAYCCNTCN CCNACNAARACNACNGCNYTNAGYYTNAARAARAARGCNACNYTNYTNTGYCARAARAGY CCNATGAARACNYTNCCNYTNCCNGCNACNGCNAAYTCN------GGNGAYGCNCCNAAY TTYACNCARTCNAARATGYTNACNMGNTTYCARAARGGNMGNACNMGNTCN--------- ---------------------------AARAARAARGARGARCCNMGNCAYGCNGTNGTN AARMGNGTNAARAARGTNGARGARGAYTCNGARAGYGCNAARGARGCNGARAGYGARGCN AGYGARGTNGARGARGCNGGNGGNYTNTCNCARGARGAR---GAYGARGAYMGNGTNAAR YTNGAYGAYYTNATGGCNGCNAGYACNACNATHAGYTTYGGNTCNAARAAR---CCNTCN AARGAYGARGAYGTNMGNAGYAARGCNGAYMGNAARAARGCNATGTCNYTNTCNYTNYTN CARCCNGAYYTNGTNCARTCNGAYCCNAARAARGAYGAYMGNGAYACNGCNTTYGCNCAR CARTAYTTYAAYCARGTNAARGARACNYTNTCNTCNGAYTCNGARMGNTTYTAYAARTTY YTNTCNYTNYTNAARGAYYTNAAYAARGAYCAYACNAAYCCNGTNGARYTNTAYYTNGAY ATGGTNTCNYTNYTNTCNGAYCAYCAYCARYTNGTNGARGAYTTYGGNGGNTTYYTNYTN TCNTTYCARGCNACNGARTGYAARTGYTTYTCNACNAAYTCNCARTAYGCNCARATHMGN CARTTYYTNMGNCARATHGARATHCAYTGYGGNTCNTCNAAY------GCNTAYYTNAAR GTNYTNMGNGCNYTNTCNAARTGGTCNTCNATGTGYCARGARGGNAARYTNGAYGGNAGY YTNMGNGAYAARATGATGGCNATHYTNAARAAYGTNCCNGGNGTNYTNGAYAAYYTNATH AGYTAYTTYYTNGAYAGYACNGTNACNAAYTTYCAYAGYCARGAYTTYGARGAYATHTGY YTNGAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATHCCNGARCCNAARGTNACNAAYGTNGARGCNMGNAGYGCNAARATHAAR YTNTCNCCNCCNGAYTGYGGNGAYGCNATGGAYYTNTAYCCNTCNGAYYTNAARTAYGAR YTNTTYYTNTCNGAYAGYGGNMGNGAYGAYAARTAYGAYTCNGTNTTY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYGARATGYTNMGNYTNYTNYTNGARTTYGGNGCNAAY GTNAAYGCNTGYGAYAGYGARATGTGGACNCCNYTNCAYGCNTCNGCNACNTGYGGNCAY GTNACNYTNTGYAARCAYYTNATHGAYAARGGNGCNGAR--------------------- ------------------------------------------------------------ ------------------------ACNGAYACNGARGAYGTNMGNYTNMGNAAYACNATH AGYATHGAYCARGARAAYACNAARGAYTCNGTNGCNTCNGAYTCNGTNCCNGARGGNCCN ACNCCNTCNAAR---MGNATGMGNGGNTAYMGNGARGGNYTNGGNGAYGTNYTNGARCAR TCNATHTGYGTNTTYACNGCNGARAARYTNTTYGARTAYCARTGGCCNCARGAYGGNGGN GAYTGGTAYYTNGTNCARGARCAYGTNAGYGARTAYYTNAARGTNAARTCNTTYAARMGN AARTAYCCNGAYYTNTAYMGNMGNGTNTGYGAYAARGARGARAARGAYTTYYTNMGNGAR AARGGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNCAYGGNYTNACNGAYGCNGTNGAY CARAGYGTNCAYGAYGTNAARTTYATHTCNGCNGARGARACNAARGARGGNAGYTGGATG TCNAAYTCNAARGCNATHTGYTTYGGNGGNGGNTTYGAYYTNGGNTTYATHGARTCNYTN GGNCARTGYGGNATGMGNAAYATHMGNGARTTYGTNAAYMGNGGNGGNTCNTAYYTNGGN YTNTGYGCNGGNGCNTAYTTYGCNTGYGAYTTYATHGARTTYGAYAARAARGGNCCNYTN GARGTNTGYGGNGARMGNAGYYTNAARTTYTAYCARGGNAARGGNATHGGNCCNGCNTTY CCNGGNTTYGAYTAYCAYTCNMGNCARGGNGTNCAYGCNGTNCCNGTNYTNTAYMGNAAY GGNYTNGTNGAYGCNTAYATGGARGGNGGNAGYTAYTTYYTNCCNTAYGAYAARTCNTCN AARAGYAGYAAYACNGARGTNYTNGGNAARTAYAARTCNYTNGARGGNGTNCCNGAYGCN GTNGTNAARTGYACNTTYGGNCARGGNACNGCNGTNYTNTCNGGNGTNCAYTTYGARTTY TCNGCNTAYCAYYTNAAYAAYGARGAYMGNTAYYTNAGYAARYTNYTNCCNGAYTTYYTN YTNGCNGARGGNAARMGNAARTAYGTNTTYAARGAYYTNYTNTGYCARYTNGGNATHAAY TGY---ATGGCNAARMGNGGNCCNCARTCNGTNYTNAAYCAYGAYAAYTGGGAYAAYGAR GAYGAYGCNGARGARGCNGGNATHTTYAARCARGCNACNAARAGYGCNATGGARCARMGN GTNATHAARAARGCNAARMGNMGNGGNGGNGAYGAYGGNGGNACNGCNTTYGGNGGNTTY GGNGGNTTYGGNGGNYTN---------AAYCARAAYACNACNGCNAARAAYTCNACNTCN TTYAARYTNAGYACNGCNACNGCNGAYCCNGTNAARCCNAARYTNTTYAGYGGNGCNACN TCNCCNTTYGGNAARGTNGARAARTCNTCNCCNGCNAARTCNGARTCNAARGAYAAYTCN ACNTAYYTNCAYGGNYTNAARTCNYTNAAYGARGGNGTNYTNGCNTGGATHAARCARCAY GTNGAYAARAAYCCNTAYATHATHYTNACNCCNATHTTYAARGAYTAYGARAARTAYYTN GCNACNYTNGARTCNAARAARAGYAGYTCNACNACNACNACNACN------------AAY GGNTCNGGNTCNACNGARAGYTCNAARGCNGCNCCNYTNGGNACNGCNTCNCCNYTNTCN AARGARGAYGCNAARAARGAYGARAARGARGARGARAARGARAARAGYCCNAARAARGCN TCNGCNGCNGTNTTYGCNTTYGGNTCNACNTCNTCNGAY------GGNGAYGGNTTYAAR TTYTCNTCN------TCNTCNACNCCNACNACNGGNTTYGCNTTY---------GGNAAR ACNTCNACNACNTCNGCNCCNTCNTCNACNTTYACNTTYGGNCARAGYAGYGCNACNACN GCN------ACNCCNGGNTTYTCNTTYGGNACNACN------------AGYACNAGYGCN ------------------ACNTCNCCNACNGCNTTYGGNGGNGCNGCNAGYTTYTCNTTY GGNACNYTNGCNGCNAAYTCNYTNGCNGCNGCNCARGCNTCNCARGARGAYGAYGARTAY GTNCCNCCNAARCCNGARGTNAARGARATHAARGARGAYGGNTCNYTNTAYTCNAARMGN TGYAARYTNTTYTAYCARAARGAYGGNCARTGGGCNGARMGNGGNGTNGGNAAYGTNCAY ATHAARCCNYTNGARGARACNAARACNCARATHYTNATHMGNGCNGAYACNAAYYTNGGN AAYATHYTNYTNAAYATHATGGTNACNTCNGGNYTNCCNGTNTCNMGNCARGGNAARAAY AAYYTNYTNYTNGTNTGYGTNCCNAAYCCNCCNATH---AARGARGGNCARGARGGNGAY CARAAR------CCNATHTCNATGYTNATHMGNGTNAARACNGGNGCNGARGCNGAYGAR YTNYTNACNACNYTNGARGARMGNAARGCNYTNYTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------MGNGGN ACNYTNTCNYTNAARGAYGCNYTNACNGAYATGACNGCNGARAGYGARCAYGTNGARATH GARGARYTNCCNGAYACNGARGCNCAYAARGGNATHATGCARGCNGCNCAYTTYGTNTTY ACNMGNYTNGAYGARYTNAARATHYTNGARCARGCNTTYGAR---CARTAYAARGAYTAY CARYTNGTNGTNACNGGNCAYAGYYTNGGNGCNGGNGCNGCNGCNTGYGCNTCNYTNYTN YTNMGNCCNYTNTAYCCNAAYYTNGTNTGYTAYGCNTTYTCNCCNCCNGGNGGNYTNYTN AGYCCNCCNYTNGCNCARTAYACNCARTCNTTYGTNTGYTCNGTNGTNYTNGGNAARGAY YTNGTNCCNMGNYTNAGYYTNYTNGGNATGGARGAYYTNAARGTNAARGTNYTNCARCAR ATHAARGAYTGYCARAARCCNAARTAYAARATHYTNGCNAGYGGNYTNTGGTCNTTYATH TGYGGNAGYGCNAGY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNTCNCCNTTYACNCCNATGCARCCNTAYAAYGAY ATGAAYACNCCNGAYYTNAARAGYCARYTNTCNMGNATHGGNGTNAARCCNATGGGNAAR AARMGNATGMGNGAYTTYYTNGTNGAYGTNTAYAARCARACNCAYCARTAYGARACNGAY TCNGAYTAYGARGCNACNCCNAARAARMGNCCNAARCCNACNAARATHAARTCNACNAAR GAYTCNCARATHCCNCCNGGNACNGCNGTNAARGTNAARGGNMGNAGYGAYAARGAYGCN GGNAGYTCNGCNGGNAGYTCNGAYTTYTCNTCNGCNGAYGARGTNAAYAARACNAAYMGN MGNATGAARACNAGYGGNGCNGGNGCNAARGGNCCNGCNGCN------------YTNGTN AARAARTCNTCNAARGCNMGNGTNATGGCNMGNCARTCNCAYGTNAARCARGCNGGNGAR MGNGGNGGN--------------------------------------------------- GGNGGNGTNGARGGNGAYGAYGGNGARYTNYTNAGYTCNCARGAYTCNTGYGAYAGYGAY GGNCCNGAYYTNCCNGARGARAGYATHYTNCARTGYTGGCCNGARGARGAR------GAR ACNGARCCNACNCARYTNACNCARACNAGYYTNGARGTNYTNATHGAYMGNYTNATGGCN TTYYTNMGNGAYAGYCCNGCNATHTAYGAYAARATHYTNATGTAYGARGCNYTNGARYTN GAYGTNYTNAARAARCARATHGGNGAYGCNGGNATHMGNATHGGNATHGGNMGNYTNCAR GAYTTYYTNGAYGARMGNTGYATHACNTTYTCNATGAARAAYATGAGYAAYMGNAAYAAY MGNCARCCNGCNAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATHGCNGTNCARCAYCAYGARMGNAARYTNAAYYTNMGNGTNYTNAARGCNTGG TTYGGNYTNGTNCARAAYMGNTGGAARACNMGNGTNGARMGNAARTGYGARACNCARGCN AARGGNGTNTGYYTNGAYYTNACNAGYGAYTAYGARACNAARATHTGYATGYTNAAYAAR ACNATHGCNTCNYTNGARTGYAARGTNTCNYTNYTNCARGAYGARAARGARGCNTAYTCN AARCARGTNAARACNGCNTTYATGMGNGGNATGTGYGCNYTNAAYATGGARACNATGTCN GTNATHGGNGAYGAYGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG GGNMGNAARAARATHCARATHGCNMGNATHAAYGAYGARMGNAAYMGNCARGTNACNTTY ACNAARMGNAARTTYGGNYTNATGAARAARGCNTAYGARYTNAGYGTNYTNTGYGAYTGY GARATHGCNYTNATHATHTTYACNAGYAAYAAYAARYTNTAYCARTAYGCNAGYTCNGAY ATGGAYAARGTNYTNYTNAARTAYACNGARTAYAAYGAYACNGTNGTNAGYCARACNAAY AARGAYATHATGGAYATGYTNGAYAARAARGARAGYAARGGNGGNGARCAYGGNGGNGAY GAYGAYGAYTTYCCNATHTCNCCNMGNACNGAYGARAGYTAYMGNAARATHGAYGCNGAR TTYGCNMGNGCNATGAAYGAYGGNGGNYTNAARCARTCNCCNGTNCARTAYCARATHCCN GTNCARTCNGGNACNGCNCARTAYACNGCNGCNCCNGCNAGYATGGCNAGYGGNGGNTCN GTNATHGTNYTNCARCCNTCNGGNCCNGTNGCNAAYACNATHAAYMGNCARCARGCNACN MGNGTNGTNACNGCNTCNCCNAGYAAYACNGGNCARMGNGTNACNGTNAAYGTNAAYACN AAYGCNTCNACNGGNGCNCAYCCNGTNTCNYTNCAYATGGCNGGNGAYYTNCCNMGN--- ------------------------AAYACNTCNGTNACNACNGCNGCNAAYAARAARCAY GGNYTNAARGTNGTNATHCCNGAYMGNGGNCCNGCNGTNTCNCARGGNAARGTNCARCAR GGNACNGCNYTNGAYACNCCNAGYGTNTCNATHGCNACNCCNAAYAGYCARAAYGCNGCN CARGGNGCNATHCARGCNATHYTNCARTCNGGNGAYYTNYTNGGNAGYGCNGAYATHACN GGNYTNTCNCCNYTNGTNTAYCARYTNACNAAYCARGGNCAYGTNCCNGGNCCNYTNACN GCNGCNYTNCARGCNTCNGGNGTNTTYACNCCNGGNGGNTCNYTNTCNATHTCN------ ------ACNCCNATHATHACNYTNCCNGCNCAYAARGGNGARYTNGTNAARCARGAR--- CCNGGNTCNCCNCAYAARCAYGAYCAYTCNTCNGARMGNTCNTCNAAYGARCCNCCN--- ------------------------------------------------------------ ------TGYTAYAARTGYAAYGGNMGNGGNCAYTAYGCNMGNGAYTGYMGNAAYGCNATG GGNGGNGGNGGNGGNCARGGNTAYGGNGGNGGNGGN---------CARGGNCARGGNGGN TAYGGNGGNCARAARTGYTAYAARTGYAGYMGNGTNGGNCAYTTYGCNAARGARTGYACN CARGAYCARGARMGNTGYTAYAARTGYAAYGGNYTNGGNCAYATHGCNAARGAYTGYGAR AARCCNATHTCN---ACNGGNGCNTGYTAYAAYTGYAGYAGYAAYGAYCAYYTNCARMGN GAYTGYCCNCARGCNATHGTNAARTCNTGYTAYGCNTGYGGNCARTCNGGNCAYYTNGCN AARGAYTGYTCNGGNGGNTTYGGN------------GAR------------GAYAAYMGN AARTGYTAYACNTGYGGNGGNGTNGGNCAYATGGCNAARGAYTGYCCNACNCCNGCNAGY AARAAY---------TGYTAYAARTGYAARAGYACNGAYCAYYTNCARAARGAYTGYCCN TCNTCN---YTNAAYACNACNCARTGYTAYAAYTGYAAYGARACNGGNCAYATGGCNMGN GAYTGYACNGCNGAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------CCNGAYTGGGTNCCNGCNGGNTAYYTNGARAARGTN ACNGCNYTNTAYGAYTAYGCNAARGARGCNGARGAYGARYTNGCNTTYTCNGARGGNGAY GTNATHTAYGTNACNGGNMGNGAYGAYTCNGGNTGGTGGCAYGGNCAYTGYAAYGGNGCN TCNGGNTTYTTYCCNCAYAAYTAYATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGGGN GGNAAYATGACNGTNGARMGNYTNCARTCNAGYATHYTNGARGCNTTYCARCAYGCNGAR GARTCNAARAARGARGCNGGNAARAGYTTYGTNTCNTGYGARYTNATGACNCAYCCNGGN TAYCCNACNGAYMGNAAYGGNGGNGGNTTYGAYGGNTGYTCNGAYGAYTTYGGNTGYTCN GCNGARMGNGARCAYGARATHGGNGTNYTNACNTCNAARCARATGGCNGAYTTYTAYGAR GGNAAYGGNATHATHYTNGCNTCNCAYGARATHYTNATH--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNCCNGARCCNGARCCNGAR CCNGARCCNGARGTNCCNACNGGNCCNCCNCCNCCNAARCCNGGNGAYGARGARTGGGAY TTYGTNGAYYTNGAYATHGAYAAYGARYTNGCNMGNGTNYTNGTNTCNCAYTGGGARGAR ACNGARAARTCNTAYGTNAAYAAYTGYAARCAYGTNTTYMGNMGNGTNMGNGGNGARMGN GARAAYATHTAYMGNTAYTTYTTYCARATHMGNAARGAYTTYYTNCAYTAYYTNMGNMGN CCNGAYTGYAARCARGAYTAYGTNTCNCARTGGCARAARACNTAYAAYGARGTNTCNGAY GAYATGMGNGAYGAYGARGARACNAARGCNGARYTNCAYCARCARGTNGAYGAYYTNMGN GARMGNYTNTGGAAYATHTGYGAYGARMGNAARGARCARGCNGARAARGARMGNGARACN AAYATGAAYGAYGGNTGGYTNGARGAYMGNYTNGGNGTNYTNAGYAAYCAYTAYYTNACN GTNATGCARTCNGARGTNGAYMGNYTNCARGAYACNGTNMGNATGYTNAARGAYTAYTAY MGNGGNATGGAYGGNCARGTNCCNGGNGARYTNAAYCCNGAYTAYGARMGNGTNCCNYTN ATHGARYTNCCNGTNGARMGNCCNGARACNCCNGAYGGNGTNMGNAGYGARACNGCNCAR TCNCCNGTNGAYGAYGCNAARTCNGAYMGNTCNGTNTCNGCNMGNTCNAARTCNCCNMGN GGNAGY---MGNTCNAARTCNCCNAARGAYMGNGCNAARTCNCCNAARGGNTCNMGNTCN TCNMGNTCNGCNTCNGGNAARAARAARGCNAARGGNGGNAARGARACNCCNCARCCNGAR GCNCCNAARTCNTCNGARGGNATHGGNMGNMGNATHATHATHCCNYTNGTNCCNMGNMGN CCNGCNTCNCCNGAYGCNGARATHAARATHGGNACNACNCCNAGYAARGARAARAARGAY AARAARGGNGTNAARAARGGNGCNTCNGCNACNGAYGAYYTNCCNGGNGCNGARAGYCCN GCNCCNCCNCARGAYATGGAYGARAARYTNATHTAYGAYGGNTAYACNTTYGCNGTNAAY GGNYTNACNCARATGATHCARTTYGARATGCARGCNMGNGARGCNGARGARGARGCNGAR AARYTNMGNGARCARGARAARGARMGNGARAARGARAARGCNAARGGNGCNAARGCNGTN AARGGNGGNAARAARGGNAARAGYMGNAGYCCNTCNCCNAARAARGGNGGNAARGGNAAR GARTCNGARACNTCNGCNACNCCNCCNCCNGCNCCNTCNGARGTNAGYGARGARGAYYTN CARMGNMGNTCNTGYMGNGARMGNGCNMGNGARGARTAYTAYTTYTCNATHCARGARGAR GARCARGCNACNAARATHMGNYTNGARYTNATHMGNATHYTNGCNTGYGCNGTNYTNCAR GAYYTNAARGGNAARGGNGARGARGCNTTYAARAAYATGAAYGAYTGGYTNGGNGCNMGN TTYYTNAARGARATGGARAGYATHGAYCARATGTCNGARGTNATGMGNAAYGCNATHGAR GTNAARGARAARYTNAARACNGARATHYTNYTNGTNCARGAYGAYTTYGTNGTNGAYGAR GAYYTNAARATHYTNMGNACNCCNAGYCCNCCNYTNYTNCCNCCNCCNAAYGARCARCCN ACNGCNGARCAYTTYACNGTNGCNCARYTNTCNACNYTNTAYGARCARTTYAARGCNTCN GCNCCNACNGGNATHATHTCNAAYAARGCNTTYATHGARATGTTYGARAAYATGGTNTCN GTNACNCAYGGNATGGARGCNYTNCCNGAYATGTGGACNCAYYTNTCNCCNCCNCARATH CARGARYTNGCNGCNATGYTNTCNTCNGARACNGAYTAYGTNGAYTGGMGNMGNYTNYTN GTNGCNYTNTGYCAYCCNATHCCNACNCCNACNCARCARCARYTNYTNGAYATGYTNGCN MGNTTYAARAAYATGGAYCARAARAAYACNGGNACNGTNACNMGNGARCARTGGCARMGN ATHCCNYTNTGGTTYGAYGTNGAYTCNACNCARGAYTCNGCNTAYAARMGNYTNGCNTAY ATHAGYMGNGCNYTNTTYGARATGTTYGCNGAYCAYAGYGGNCCNATHTCNCAYYTNTAY TAYGAYAGYTTYYTNATGTAYTTYTCNGCNATHGCNAAYTAYCAYGARGGNTTYYTNMGN GCNYTNAGYATHGCNTCNTGYCARCAYATHCCNMGNYTNGGNAARCCNTCNYTNGTNTCN CARACNACNCARYTNGGNGARMGNGCNTCNAGYGCNGTNGAYAGYTTYATHCARGARGGN ACNGARTAYAARGAYGARGAYAARCCNCCNTCNGARCCNCCNATGTCNGAYGARGTNATH CCNCCNGARGCNAAYGAYGCNGTNGTNTCNGTNGAYGAYYTNTTYAARGTNYTNCAYCAY GGNGARATHTCNAARGGNGAYAGYCAYMGNTTYAGYGTNACNGCNGAYCCNGARGARCAR ACNTCNTAYGARMGNYTNAGYGCNGTNTTYCARGARYTNAAYGARGAYGAYAGYACNTCN CCNATHCARTAYAARATHYTNATHGAYCAYCCNYTNATHCARGAYGTNGTNGTNGCNTGY AARCAYTTYAARGCNYTNGAYATHAARAGYATHYTNGCNGGNTCNTCNCAYGAYGCNGCN GARATHACNAGYYTNAARACNATGGAYGGNTCNTGYTTYTCNACNYTNCARGARTTYTCN GARGCNYTNGARMGNTTYTCNACNAGYTCNTCNACNCARTTYGTNAARMGNACNTCNMGN AARATHAAR---GAYCCNGCNYTNGCNCAY---YTNGARYTNGARGCNGCNACNTAYTGY TGYAARCAYGGNAARGCNTGGCAYCCNTCNGCNTCNACNGGNGCNMGNCCNAAYCARAAR TCNTTYAARACNGGNTGYACNGCNACNTTYMGNGTNMGNTGYGTNMGNCCNAARAAYGGN GAYGCNYTNMGNYTNTCNAARGCNGAYTTYACNCAYACNGGNCAYGARGTNTCNCCNCAY ATGTTYCARTCNTAYCCNGARCARMGNMGNTTYTGYGGNGAYGCNGCNGAYCARMGNATH YTNTCNTCNAARATGAARATGTCNGARMGNAARGARYTNYTNCARAAYMGNCAYGGNGTN GCNGTNAARACNCARGAYGTNTAYAAYAARMGNMGNAARYTN------------------ MGNYTNMGNCCNYTNGTN---YTNGGNYTNGCNMGNMGNACNGGNCARAAYYTNCAYACN ACNTCNMGNAARTCNGGNGARGCNYTNTAYMGNGARAARATH------TTYGAYTAYAAR GARCCNCARTAYATGCARTAYGCNGGNACNGCNTTYAGYGCNTTYATGTGGTAYTGGATH YTNTAYCAYTGYTAYTTYGARTTYGARCAYYTNGTN------------------------ ---------------------ATGCCNGTNGARGAR------ACNTTYTTYAAYAARYTN GGNGARATHCCNYTNGTNAAYGAYGGNTGGTCNACNGCNACNGGNTAYTAYTCNAARYTN AARGAYTAYAAYGCNYTNATGCAYYTNGCNYTNACNATGGCNGARTCNAGYGTNAARGTN GCNGGNCAYATGTCNACNCCNGTNYTNAAYCAYTAYCARCCNCARATHGAYAAYATHAAY GAYTAYGCNTGYAARAARYTNGAYGARYTNGARAAYAARTAYCCNTCNATHAARCARCCN ACNGARCARTGGAARGARACNTGYACNGGNTAYGTNGARCCNGTNGTNGGNCARGTNAAR CCNGTNATHACNCARGTNCARGGNATHGTNAGYAAYGGNAARCARAARATHGTNAAYATH AARACNGCNAGYAARAAYATGGTNGARGGNGCNAARACNATGGGNGTNGGNACNGCNACN CAYGTNTTYAAYGCNACNTTYGARACNGTNCCNGGNMGNTTYGTNAGYMGNACNGTNGAY AGYGCNYTNGAYATGGCNGAYGGNYTNGTNGAYMGNTAYYTNCCNGARGARAARGARGAR ATGGCNGARAARAAYTGYTCNGAYGAY------------GARAGYGAYGCNGAYAGYAAY GGNAGYGARCAYGCNGTNGARGARATGCARATHATGGAYCCNACNCCNAARMGNGTNYTN GTNCAYGCNAGYTGYGTNACNGARAARATHMGNMGNMGNATGTTYMGNMGNGCNGTNAAR GAYYTNACNTAYGCNAARGCNMGNACNACNTCNGCNYTNATHMGNATGCARAARACNGTN ACNYTNATHGAYTAYGCNAARAARAAYGTNGGNAAYATGAARGARAARGTNGAYGAYATG TGGACNGARATHATHAARGARAGYGAY---------CCNTCNATGAARGARAARACNGTN TTYGCNGGNACNGTNGARGAYMGNATHGTNGCNYTNGGNMGNATHGTNGCNCARCARGTN MGNTCNAAYGTNACNACNTTYGARAARGTNTTYTCNGARYTNGGNGARTTYCAYAARAAY CCNATHTCNAARACNAARGARTAYAARGAYYTNATHGARACNTTYYTNACNGTNGARTCN ATHCARAAYTTYTCNTCNCARAAYYTNGCNAARGCNAAYGARTCNYTNAARTAYATHCAR AAYATGATHCAYTCNGTNGTNACNAAYGTNGCNTCNYTNAAYTGGGTNGCNATGGAYATH GAYATGGARGAYATHCCNYTNGARGAYAAYGAYYTN------------------------ ---------------------CARAAYTGGAARGGNGTNATGMGNAAYGARGARGARTTY GGNGTNGAYATGTTYATGMGNYTNTTYAARAAYGAYCARAGYYTNCARATGATGTTYCAR ACNTTYAARGAYATHMGNTCNGAYGAYGARYTNMGNAGYAAYGARGCNYTNGARTAYCAY GCNTCNGTNGTNATGGCNACNYTNGAYGARGCNATHACNCAYATHGAYAAYTAYGAYTTY GTNTAYCARYTNYTNTCNACNACNGGNGCNTCNCAYAARMGNTTYGCNGGNTTYAARGCN AAYACNTTYYTNGCNATHAARCARCCNTTYYTNGAYGCNGTNAARGTNACNYTNGGNGAY MGNTAYACNGAYAAYATGGARAAYATHTAYACNATHACNATHAAYTTYYTNGTNGAYACN ATGGTNAARGGNYTNCAYGAYGCNYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------CCNYTNCAYGAYGCNATHMGNGCNCAYGAYGCNGAYGTNGTNMGNYTNYTNYTN GAYAGYGGNGCNGCNGCNAAYGTNCCNGAYAARCAYGGNATHCARGCNATHCAYTGYGCN ATGAARTGYGAYYTNGAYACNGTNAARACNYTNATHGARAAYGGNGCNGAYYTNGAYGCN AARGCNGARAAYGGNYTNACNCCNYTNCAYGTNGCNGTNGTNTTYGGNAAYTAYCARGTN GCNTCNTTYYTNGTNAARGCNAAYGCNGAYGTNAAYGCNGTNGAYCARATGAAYAAYACN CCNACNGAYYTNGCNGARATGAARGGNAAYGARGARTTYYTNACNYTNYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---GCNACNYTNGGNGTNGTNGCNTCNGTNYTNCCNGGNGTN---TCNGCNYTNAGYGAR ACNGCNCCNATHATHGCNGCNGGNGTNGTNGCNTGYTTYATGYTNYTNATHGTNATHACN GTNATHGTNTAYGCNGTNTCNTCNAAYTCNTGGGTNAARTCNTCNATGAARTCNGARGGN AARGTNAARATGCCNMGNTCNTAYTGGGARMGNAARMGNGARGCNAARMGNAARYTNATH CARAARMGNYTN---YTNGCNAAYCARTCNGTNMGNTCNTCNMGNGGNACNCARGAYACN TTYGTNMGNTCNGTNCCNTCNGTNAAYGGNAGYATGGTNCARGGNTGGAGYMGNGAYACN MGN---------AARATHTAYGARGARAARGGNTAYACNATGGARYTNGGNGARGARMGN GAYGARGARTTYCARATHGARACNACNATHGTNGAYAAYGARGTNYTNGAYGTNGGNCCN TAYCARAGYGTN---GCNATHGGNGAYGCNGARCCNGTNGAYGGNAAYGTNTAYGCNAAR CCNTAYATHTAYTCNAAYAARGAYAARGTNGTNTCNMGNAGYACNGAY---GCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GTNTAYYTNGTNGGNMGNGARGARAGYYTNGGNCARGARYTNAARGAYGTNGGN ATHCCNTAYATHGGNACNGGNCCNGARCCNYTNAARAGYACNGARGTNCARGAYTGGYTN TCNACNGARYTNGAYCCNGARGTNAAYTGYGTNGTNGTNGGNTTYGAYCCNCAYATHAGY TTYATGAARATHYTNAARGCNGCNAGYTAYYTNAARAAYCCNGAYTGYYTNTTYATHGGN ACNAAYGARGAYGGNTGYYTNCCNAAYAARGGNAARATGTGYATHCCNGGNACNGGNTGY ATGGTNGCNTCNGTNGCNATGGCNTCNAAYMGNMGNCCNATHGTNGTNGGNAARCCNGAR ACNGGNATGTAYGAYGTNYTNAARGGNYTNCAYAAYYTNAAYCCNTCNMGNTCNYTNATG ACNGGNGAYMGNYTNGARACNGAYATHGTNTTYGCNCARAARTGYGGNATGAARTCNTTY GCNGTNYTNTCNGGNGTNTCNACNMGNGARGARGTNTCNGGNGAYAARAAYACNATHACN CCNGAYTTYTAYGCNGAYTGYYTNGGNGAYYTNGGNAAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATHAAYGAYMGNAARMGNAGYGGNGGNCARATHATGMGN GAYAAYGAYYTNAARMGNGGNMGNMGNGAYTCNTAYGGNMGNGGNGARMGNGAYMGNAGY GGNAAYMGNAGYAGYAAYAGYGCNGGNCARGAYMGNGARMGNAAYMGNTCNAGYCARMGN GAYTCNGAYMGNAAR---AARMGNCAYGGNGARGAYTAYGAYCCNGCNGARCCNACNGAR GAYGAYGAYGARGGNAGYGGNAAYAARAARGAY---TCNAAYYTNTAYTGYCAYGTNTGY TCNGTNTCNGTNTAYGAYGARGARAGYTTYCARMGNCAYYTNAAYGGNYTNAARCAYAAR GCNMGNATGGARAGYYTNACNACNGTNCAYCARATGMGNTCNACNCARYTNAAYTCNMGN YTNAARGCNGARGARCAYYTNMGNAAYATHGARMGNAARGGNGGNMGNGAYCCNGAYTAY TTYTGYAARATHTGYAAYAAYGAYYTNGCNATHCCNTGGGARAARCAYMGNTAYTCNAAY ATHCAYAARCARMGNYTNYTNCARGTNMGNAARGGNTGYGGNTGGTGYAARGTNCAYAAY TTYACNAAYTTYTCNGARGTNYTNGARCAYMGNGARACNGAYGARCAYAARAARAAYTCN GAYYTNTAYGGNAARAARGARGAYGARAAR---GAYGGNCAYAAYMGNTCNCAYGAYGAY ------------GARAARGAYGGNAARGTNTCNGAYGGNAGYAARAARGAYGGNGCNAAR AARGAYGARGCNGARGARGARGARGARGARGARGAYYTNACNATHCCNGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARATHGGNGGNACN GCNGTNTGGATGTCNAGYAGYAGYGAYACNACNAAYCCNACNTGYCAYGGNTGYGGNCAR GAYMGNACNYTNGTNGTNCARYTNTAYTGYCCNYTNGCNAAYTCNGCNTAYCAYMGNTGY YTNTAYGTNYTNGTNTGYTCNTCNATGGGNTGYCCNCARCAYAAYAGYTGGAARGTNTAY MGNGGNATGCARTTYGAYCCNTCNTAYTCNCARGARAARAARAARGTNGTNCARGAYTTY AGYGAYGAYYTNTGGACNGAYGAYCARAAYGAYTGGGGNGAYGGNGGNGAYGAYGAYGAY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GGNGGNTGGYTNYTNTAYMGNTAYATH YTNAARAARGTNCARGARATHGGNGAYGARCARGARAARMGNTAYYTNATHAGYGTNMGN MGNCARCAYCAYTTYGAYAGYAAYCARMGNACNTGYAAYGTNACNGTNYTNTCNATGGTN CCNAAYATHMGNGARACNYTNGTNAARAAYYTNGAYGTNGARGCNGTNAARGARATGYTN AARTCNAAYCCNCCNAAYAARYTNGARYTNTGGGARGARYTNAARYTNATGAGYGTNACN MGNTCNYTNGCNGCNGTNTAYGGNACNTGYATGYTNTCNGTNATGYTNMGNGTNCARYTN AAYATHGTNGGNGGNTAYYTNTAYATHGAYAGYYTNCAYCCNGCNAAYGGNCCNCCNGCN GAY---GGNAAYGTNGTNCARATHTCNCARMGNGTNCARGARMGNTAYYTNTCNGTNGTN AARGARTTYATHGARCARGGNTTYGTNGAYTTYATHCAYGGNYTNAARYTNGCNGTNATH AARGARTTYGGNGGNATHGCNYTNAARGARCARYTNGGNYTNGAYAAYYTNATGTCNGTN TTYGCNCAYGTNMGNGARMGNATHGARTGYGGNGTNGAYAARGCNACNATHTCNYTNTAY CCNTAYYTNATHAARAGYGARCARGTNCCNGTNTCNGAYTCNAARACNGCNATHGAYCCN GAYGAYGARATGTAYGARAARYTNATHAGYGARACNMGNGAYATHYTNGARAGYTAYGAY TTYCAYTCNGTNYTNAARGAYAGYATHGAYMGNGGNTTYCAYTGYATHYTNGAYACNYTN GCNGAYCAYTAYAARCARGTNATHGTNCARGGNAAYTCNGAYGTNAGYATHCAYGAYGTN TCNATHGCNATGGCNAARYTNATHCCNGTNATHAGYTCNYTNYTNCCNAARATHTGYGGN GAYGCNCCNAAYGCNTTYGTNCARGARYTNATHYTNATGAARGARGTNAARCARYTNGCN GCNAAYGTNTAYGARGCNTTYAGYCARGAYTCNAGYGARAARCCNMGNTTYATHGARYTN GTNTGYCARAAYCCNYTNYTNTAYGAYCCNACNGCNAARAAYAGYGAYYTNGARTCNACN AARGCNGTNTGGGCNMGNATHGCNGCNGARATGAAYGTNCCNCCNATGTGYGTNCAYGAY TGGAARTGYAARTGGAARTGYYTNMGNGAYACNTTYGTNAARAARMGNMGNGAYATHMGN TAYGCNGARAARCARGARCARATHGAYAARCAYTGGAARTTYTAYMGNAAYATGTCNTTY YTNGARCCNTTYGTNACNMGNTTYCAYAARACNATHCCNGGNGTNGARTTYCARGAYCAY TAYACNAAYGARGARTAYGARGAYGARGAYGAYTCNGGNGGNGARGARGARGARGGNGGN GAYGARGAYACNCCNGTNAGYMGNMGNMGNACNMGNCARGCNCCNCARACNGGNATGAGY CCNAGYGCNAAYACNGARGAYGAYACNGAYTCNAAYATGGARGGNAGYAAYTCNAARAGY TTYTTYCARTCNTGYTCNTAYMGNYTNGAYAARYTNCCNGAYMGNATHCARTCNTAYYTN CARTTYCARATHTCNCARYTNTTYTTYAAYGCNGARAAYCCNGAYGTNCCNGCNATHCCN ATHATGCCNYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGGARTCNGCNAGYYTN AAYYTNGCNAAYCCNGTNYTNAARGCNTTYATHGGNTAYGCNGCNATHGTNYTNYTNAAR ACNGTNATHATGTCNYTNGTNACNGCNTAYTAYMGNATHTCNMGNYTNGCNTTYTCNAAY GARGARGARYTNGAYTAYTTYTAYAARGAYAARAARAAYAARACNAAYTTYAAY---AAY ---TCNGARGTNGARMGNGTNMGNMGNGCNCAYYTNAAYGAYYTNGARAAYGTNYTNCCN TTYGTNYTNYTNGGNYTNYTNTAYGTNYTNACNGGNCCNTCNYTNTCNATGGCNYTNATH CAYTTYMGNGTNTTYACNGCNTCNMGNYTNYTNCAYACNGTNGTNTAYYTNYTNAARGTN CCNCARCCNGCNMGNGCNYTNTGYTTYTTYGCNGGNYTNATHGTNAAYATHTCNYTNGCN ATHCARGTNATHATGCAR---------GGNATHTTYCARCCNCAYATHCARTAYYTNYTN TGYYTNGCNACNCCNGTNGARATHGTNYTNYTNGGNGTNAGYTTYTCNCARCCNTAYGAR GGNGARGAYGAYGAYATGCAYYTNYTNCCNGAYCCNYTNTTYTCNYTNTCNACNGAYGGN ACNTAYATHACNACNATHGCNGGNACNGAYAAYGGNMGNATHTTYATGGCN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------TGYAARGCNGTNAAYCCNACNTTYTCNGAYATHACNYTNGAYAAR GCNATHACNTTYGARATHTAYGARCCNCCNACNAAYTCNCCNGAYYTNTAYGCNCARAAR GGNGGNGARACNAARACNAARATHGGNAAYGGNCARACNYTNGTNGTNTCNYTNGARGAR ACNGTNGARTGYGARGTNTCNGGNGGNTAYCCN------TCNMGNGAYTTYGGNYTNACN TGYGGN------GAYGTNACNAGYCARACNACNCARGCNACNAARGCNTCNGTNACNYTN GAYCARACNGTNTGYCARTGYMGNGTNACNCAYGARTCNGGNTGYTAYGAYAAYACN--- GTNAARGAYTTYCAYGTNCCNATHACNGTNGTNCARGGNMGNGCNAARGTNMGNGARCAR TTYYTNAARAAYAARCAYATHTCNGAYATHMGNGTNATHGAYATGYTNGTNATHAARAGY CARATGGAYYTNGTNGARACNGCNAAYATHTGGAARCARMGNCAYCAYGTNATGATGTAY TTYAARGAYACNGTNAAYCCNAARCCNACNGAYTTYYTNAGYAARTTYTAYGARGGNCAR GARGAYYTNMGNACNTCNTCNYTNGARTGYYTNYTNGARCARYTNATHCARMGNGGNAAR ATHGARAGYGCNYTNGTNATGGAYYTNGARGGNMGNGTNYTNGCNMGNAGYCARGCNAGY YTNTCNGAYCARCARGCNGGNTTYTAYTAYGGNYTNAGYTGYCAYTAYAAYGGNYTNYTN MGNYTNGTNACNGGNGAYGAYGTNTAYACNTGYTTYAARTCNGCNGAYGGNTTYATGYTN GTNGGNAGYTGYAARGGNTGGGTNACNGTNTCN------------------ATGCAYGCN AGYGAYAGYATHTAYAARMGNATGTCNGGNCARCCNYTNTAYAARGAYAAYACNGCNGAY CCNGARYTNGAYCAYAARGTNAARMGNGTNTCNGAYAARATHTCNGARACNATGAAYGTN GTNGCNAAYGARCCNTCNYTNGCNTTYTTYMGNATHCARGARCAYGTNMGNAARACNYTN CCNCARYTNGTNGAYACNAARCAYGARGTNGARGAYGTNYTNATHAAYGTNCARGGNTCN TGYTTYGAYGCNGAYTAYGCNATHAAYGCNGTNAARGCNATGCARAGYAGYGCNATHCAY TTYCARAAYATHCARGAYYTNYTNAARAAYGCNATGTTYATGAARCARCARATHATHTAY GARGAYAAYMGNMGNAARCARGGNMGNAGYAGYCCNATGACNGGNGAYMGNAARTTYCCN YTNCCNCCNTGYMGNATHTGYGAYGCNTCNGGNGCNGGNTTYCAYTAYGGNGTNAAYACN TGYGARGCNTGYAARGGNTTYTTYCAYMGNAGYYTNACNTTYTCNTTYMGNTAYAARTGY GAYAGYGTNGGNAAYTGYGTNATHCARCAYGGNMGNGGNAARATGTGY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GGNATHCCNACNACNAAYTCNATGTTYGCNTGYYTNAARYTN GARGAYGARATHMGNGARGARAARMGNGCNAARAAYAARAAYAAYCCNCARAAYGAYAAY GGNAAYTCNAARCARCARGAYGARAARAARAARAARAAYAARGCNGARYTNAARCARYTN CARCARATGGCNTTYGGNGGNGGNAARAARAARTCNGGNAAR------------------ ---AAYTCNAAYAAYTCNAARGARGAYAARAAYTGGGAYCARTGGAARCARCAYGAYAAR GARGCNGTNGARGGNCARTTYAARGAYGAYYTNGARAARGCNYTNYTNGARAGYMGNYTN GARAARGARCARGCNGARTTYGARGGNAARGARAARAARCARMGNGTNGARGCNGGNACN GARGTNCCNGCNACNMGNGARGARMGNAARAARAARAARCARAARGAYAARGCNAARGCN ATGTCNYTNCARGARTTYAARGARATGCCNGCNGCNMGNAARACNTCNAAYTCNGAYGAY TCNGAY------------GGNCAYACNTCNCCNCCNCCNATHCAYTAYMGNGTNCCNACN TCNGARCARGAYTCNAARTTYTTYAAYAAYGTNCARAAYGAYGCNAARCARATHYTNMGN CARGAYAARATGCARGARGAYTAYMGNAARACNTAYGCNGTNGAYAAYGCNGTNGTNGCN AARYTNAARCAYGAYYTNGARYTNAARGAYACNAARATHGARGARYTNTCNAARCARATG GARAARATGCARGCNGARATGAARCARGTNAARCAYMGNAAYAARCARYTNTGYGTNATH YTNGCNCARGGNGARATGAARGAYAARGCNCARGTNYTNYTNCARGTNGAYCARYTNAAY ACNGTNAARGAYGARYTNATGGARCARGTNACNACNYTNACNGCNGAYYTNGARAARGAR AARTCNAARAAYMGNGCNYTNAARACNGARTCNGAYAARYTNAARGGNAGYAARCAYGGN AARGAYGARACNATHGARAARATHTTYAARGTNCARCARCAYGARYTNGTNTGYGCNGTN TCNTCNAARCCNTAYATHTTYGAYAARGARAARMGNGTNGTNGCNTCNYTNGAYAAYAAY TAYTTYTGGTGYAAYTTYTGYTCNTTY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GGNGGNAARGAYAGYTGYTTY AAYATGATGGCNTGYATHGCNGARGGNCAYGARATHGTNGCNYTNGGNAAYYTNMGNCCN GAYAGYAARGAYGARYTNGAYAGYTAYATGTAYCARACNGTNGGNCAYCAYGCNATHGAY YTNTAYGCNGARGCNATGGAYYTNCCNYTNTAYGTNMGNACNATHCARGGNTCNGGNYTN AAYYTNGGNMGNGAYTAYYTNCCNCARGARGGNGAYGARGTNGARGAYYTNTTYCARYTN YTNTCNCARATHAARGCNGARMGNAAYATHGARGCNGTNAGYGTNGGNGCNATHYTNTCN GAYTAYCARMGNGTNMGNGTNGARAAYGTNTGYCARMGNYTNGGNYTNAARGTNTTYGCN TTYYTNTGGMGNMGNAAYCARGARGARYTNYTNAARGARATGATHGCNTGYGAYYTNAAR GCNATHATHATHAARGTNGCNGCNYTNGGNYTNYTNCCNGAYAARCAYYTNGGNATGGAR YTNAARGARATHYTNCCNCAYATGYTNAARATGAARGARAARTTYGGNYTNAAYGARTGY GGNGARGGNGGNGARTAYGARACNTTYGTNTTYGAYTGYCCNYTNTTYAARAARTCNATH GTNATHGARGARAARGARYTNGTNATHCAYTCNGAYGAYGCNTTYGCNCCNGTNGGNTAY YTNAAYYTNMGNAARTGYCAYYTNCARGARAARCCNCARCAYGAYGCNAGYTCNTTYATH CARAAYGTNGARAAYYTNCCNATGACNACNACNGCNACNTGGYTN------GCNMGNCAR CARGCNGAYGTNGARGARGAYGAYGARTCNGCNACNACNGAYGCNCAYAGYAGYTGYCCN ---------GTNYTNCCNYTNTCNGARGARCCNTGYCCNTCNAGYGCNTCNGAYGGNGTN CAYTTYTCNGTNGCNGGNATHAARGCNGTNGTNGCNTCNGGNGGNGAYGTNTCNTCNGCN GCNGAYTCNGCNATGGCNTCNYTNAARGAYTGYATHGARAARYTNGGNCAYGCNATGTCN AGYYTNACNTCNGTNTCNGTNTAYATHCARGAYATGTCNAAYTAYTCNCAYATHAAYGCN TCNTAYATHAARYTNTTYGGNATHAAYCCNCCNGTNMGNATHTGYATHCARGCNTGYYTN CCNCCNAAYGTNGTNTTYCARYTNGAYTGYCARGGNGARTCNAAYTTYGARAAYGARMGN MGNACNATGCAYGTNCARAGYYTNTCNCAYTGGTCNCCNGCNAAYATHGGNCCNTTYAGY CARACNATHYTNACNMGNGGNAARYTNTTYGTNGCNGGNACNACNGCNYTNGTNCCNTCN ACNYTNCARYTNATHGAYGGNGGNATHGCNYTNCARAGYAARGTNGCNYTNGAYCAYGTN ATGGARAARATGGARGCNGTNTGGCCNMGNTGYACNYTNACNCAYTGYCCNYTNGTNAAY TGYTAYGTNACNAARAARGARAAYATHCCNGTNGTNMGNCARMGNYTNMGNCARAGYAAR CARAARYTNAARGAYTGYGTNAGY---------YTNTCNCCNTCNGTNCARTGYTGYGTN GTNCCNMGNYTNCCNAARGGNGCNTCNGTNGARTGGCARGTNTAYGGNTGGACNTTY--- ---------GARGAYTCNGAYGARGAR------CARGGNYTNCARTTYAARAARGARTTY CCNYTNTAYACNGTNGCNTTYGAYTGYAGYGARTAYTTYTCNTGYMGNATHGARGTNTGY TGYTCNGCNCCNGARMGNGTNGAYATGMGNCARYTNGCNGGNTAYYTNATGGARGARTAY GTNMGNGTNYTNGARTCNMGNGAYMGNATHATHGGNCARGGNYTNGCNAARATHTTYTAY CCNGCNTGYMGNTTYTCNGARAARGARYTNATHGARAGYTTYACNGGNAGYYTNCCNAAY GTNGTNGAR------AARATGCCNACNTTYTCNTTYGTNCCNGTNATHAGYYTNGARMGN GARGARCARYTNYTNGTNTGGTGYCAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATHYTNATGTCNMGN TTYACNYTNMGNGARAAYGARTGGMGNTCNACNAAYYTNGARGGNACNTTYCARYTNGAR GARGGNGARTCNGTNTTYGTNTAYTTYAGYTAYCCNTCNTAYATHGAYAGYGTNTTYCCN GCNAAYGTNTTYGGNYTNTTYMGNYTNGARGGNAGYAARATGGCNYTNCAYAAYCARGTN GARCARYTNMGNGGNCARYTNGGNAARGCNGARCAYGARMGNCAYMGNATGMGNGCNGAY YTNGAYGARTCNMGNATHGARGCNGARATHAAYGAYMGNMGNMGNAARAARYTNGCNGAR GAYGAYMGNAAYMGNGCNYTNGARCARGAYYTNATGGARATGAARACNCAYYTNGCNMGN TCNGTNGGNGCNGTNTCNGARATGGARGARYTNAARMGNMGNYTNGARAARAGYGARMGN CARMGN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG AGYGAYGARGAYMGNGARATHGAYATHGARAGYGAYGCNGAYGAYGARGAYGGNYTNAAY AGYTTYGCNTCNGTNGAYGAYAARMGNGCNCAYCAYAAYGCNYTNGARMGNAARMGNMGN GAYCAYATHAARGAYAGYTTYCAYAGYYTNMGNGAYTGYGTNCCNTCNGARGAYCARAAR GTNAARACNAAYACNTCNAGYAARACNTCNMGNGCNCARATHYTNMGNCARGCNTCNGAY TAYATHATHMGNATGMGNGARAARACNTCNCARAAYGAYMGNCAYATHCAYATHYTNAAR CARCARAAYGAYGARYTNCARTCNCAR--------------------------------- ------------------------------------------------ATHAARGCNYTN CARAARTCNCARTCNGGNGGNAARAAYYTNATGAAYTCNAAYTTYYTNGAYGGNMGNGGN GAYGAYGAYTAYGARAGYTAYGARGAYGARCCNGTNATHGCNTCNCCNCCNAARMGNAAR AARGTNAARGGNGGNCAYAGY--------------------------------------- ---------------------------------TTYYTNGTNGTNGGNYTNGGNACNCAR CCNTAYCCNGAYACNMGNCAYAGYATHGGNATGGARGCNGTNGAYCAYTTYGCNAGYMGN YTNGGNTCNCARTGGCARMGNYTNCARGGNMGNAAYGGNGGNYTNACNTGYMGNAARACN GTNACNACNGGNTCNACNTGYCAYGCNGARATHGTNYTNTTYAARCCNAARGCNYTNATG AAYGTNAAYGGNMGNAAYGTNGTNAARATHGCNCARYTNCAYGGNGTNMGNGCNGAYAAR ATHTAYYTNATHCAYGAYGARYTNGAYATGGARCCNGGNAARTGYAGYYTNAARAAYGGN GGNAGYGCNMGNGGNCAYMGNGGNGTNCARTCNTGYATHTCNTCNYTNAARTCNAGYGGN YTNTGGTTYGAYGAYAARGCN---------------------------------YTNCCN MGNYTNMGNATHGGNATHGGNMGNCCNGCNYTNAARTCNGAYGTNGTNCCNTAYGTNYTN AGYCCNTTYCCNGCNGARGAYTTYACNGCNATHTCNAARGCNATHAAYAGYGGNATHGAY YTNYTNYTNGGNCAYATHGCNGAYMGNGTN------------------------------ ------------------------------------------------------------ ---------------------TCNCCNCCNCCNGCNCCNMGNGTNGAYTCNTCNYTNGAY GTNAARTCNGGNYTNAARGAYAARGAYYTNAARGAYGTNYTNGGNGARCARAARGARCAR CARAARGCNGCNGTNGTNACNGTNGAYAARTCNGAYGAYAARGTNACNAARGCNAAYATG AAYTCNTCNGTNCARACNAAYATGAARAARGGNGTNGCNCAYGCNTTYCCNGARGCNCCN GCNAAYTAYTCNATGAARTAYAARGCNGGNGTNGCNCCNCCNMGNCCNGTNMGNAARTTY TCNGARTAYCARAARCARTTYCARTGGAARGAYGGNCAYAARGCNTCNCCNYTNYTNGCN GCNGARCARATHGTNTAYTGYAGYAAYACNGARYTNGGNCCNTAYAARACNGARGGNATH CCNAARATGTCNGARTAYMGNMGNAAYTTYCARCCNTGGAARCCNTTYGAYATHGAYGTN GAYGTNAAYTGYAAYGTNAARAAYAAYAAY------AARGAYGTNAARAAYMGNCCNGTN GTNAARMGNAGYAARAGYGCNGCNGCNGCNGTNMGNMGNGARAARGCNGAYGARTCNATG GAYAARGARGGNGARAARNNNGARCAYGARYTNAARGARAARYTNAARAARACNCAYGGN AARATGMGNMGNYTNGGNTCNGARTAYCARACNAAYTTYAARGCNCCNTCNAGYTTYTAY AAYAARGCNGGNACNTGGAARGGNGCNGAYCCNCCNCARYTNATGCCNMGNCCN------ ------------CARGARAARAGYGAYGAYAAYAAYAAYAAYGCNGCNCCNGCNGCNCCN YTNTCNAAYTGGTTYGCNGARGTNYTNGARYTNMGNMGNMGNGCNGGNGARTAYMGNAAR MGNGCNCARGGNACNCAYTTYTCNMGNGARCAYYTNGTNCARYTNATGGCNCARCARAAY GARTGYTGGGAYYTNAAYTCNCARGCNTCNTCNACNGTNMGNGCNYTNGAYYTNGARACN CCNGCNATHAARMGNCARAGYMGNGTNGCNAARAARGCNCCNYTNTCNCCNTCN------ ------------------------------------------ATHTCNTCNGAYATHGAR YTNGARGAYYTNGARGAYCARATGGAYTTYGCNGAYGARGARGARAARGCNAAYTCNGTN GCNAGYTCNMGNATHAAYMGN------------YTNAARGARGAYAARGARGCNYTNTCN CARCARCARMGNAARACNAARCARAARGCNAARAARGARGARGCNGARTAYAGYAAYGAY GARGAYGGNGARGAYGCNGAYGGNGARGARGGNMGNCARCCNACNCCNAARYTNAARCAR ATHAARGCNTTYGTNTCNMGNCAYCAYYTNGAYMGNACNACNCCNGCNGTNGGNGGNGCN YTNYTNACNTGYCCNCCNTCNAARAAYACNAARATGATHGTNACNTCNMGNTCNGGNGAY AGYTAYGTNACNGCNTCNGAYAAYGCNGARGTN------CCNCARMGNAARCCNGAYYTN GARAARYTNAARACNAARCCNATHYTNGGNCARCCNTCNGGNGAYACNCAYGCNYTNMGN GAYGAYGAYGCNTCNATHGAYMGNGCNYTNAAYACNMGNTAYATHCCNTCNCCNGCNTTY GTNAGYAGYGAYGARGAYAARGARAAYGCNCCNAGYAARAARAARGGNGGNAARGARGGN AARCCNTGYMGNYTNACNCCNGTNCARGARGGNGCNGGNAARACNTTYGTNAARCCNAAR GCNTTYYTNACNGTNGCNGAYATHMGNGCNGAYGARGCNACNMGNACNGAYGAYGAYGTN ATGTCNGTNTCNATGATGTCNGTNGCNTCNAGYTCNAGYYTNGCNTCNGARGTNYTNGAR MGNGCNMGNAARMGNCARMGNGARTTYTGGGGNAARAAR---TTYYTNTAYTTYGGNTAY GGNAGYAAYYTNYTNGCNGARMGNATHCAYATHAARAAYCCNACNGCNAARTAYGTNTCN ACNGGNACNYTNAARAAYTAYTCNTTYGGNTTYGARGTNTTYYTNAAYTCNAAR------ ---ATHGGNGGNGTNGCNACNATHMGNTCNGGNTCNCCNAGYMGNGTNATGGGNGTNGTN TGGGARATHGAYYTNGAYCARTGYTGYAAYYTNGAYAARCARGARTCNAAYTAYAARGTN YTNGARGTNGAYGTNATHYTNGARAAYGGNACNACNGTNAARTGYMGNACNTAYGARATH GAYCARCCNACNGARYTNTAYGAYAARMGNCCNCAYCCNTTYTAYAARMGNATHTGYATH GARGGNGCNAARCARCAYAARYTNCCNGARGARTAYATHAARTTYYTNGARAGYTTYGAR GAYAAY---------------------------------------------AARTCNGGN ACNMGNCARTGGYTNCAYCCNGCNGARGCNYTNATHAARGGNCAYATHYTNTAYACNGTN AARTTYYTNGGNGARTGYAARGTNGAYCARCCNAARGGNACNGAYGTNGTNAARTCNGCN ATHACNAARACNAARTTYAAYAARCAYATHAARMGNGCNGARGGNCARAARCCNCCNAAR GTNGARYTNACNATHTCNGCNGAYGCNGTNAARGTNYTNGARCCNAARAGYAARACNATH YTNCAYCARTAYCCNYTNCAYMGNATHTCNTAYTGYGCNGAYGAYAARTCNGAYAARMGN ATGTTYACNTTYATHGGNAARGCNGCNGAYAAYAAYGAYCAYTTYTGYTAYGTNTTYGAY AGYGARAARTGYGCNGARGARATHACNYTNACNATHGGNCARGCNTTYGARYTNGCNTAY AARMGNTTYATHGARGCNTCNACNCCNGAYATGGAYATHMGNAARCARTTYYTNGTNYTN CARAARAARGTNAARTCNYTNCARTAYGARAAYGAYGCNYTNAARAARMGNYTNAARGAR GTNGARGARATGAARGAYMGNTCNGAYGTNGARMGNTAYAARCARGAYMGNCARYTNTAY GAYATHACNAGYGTNAARYTNAAYYTNMGNGARAGYTCNACNGAYGAYGARGAYAGYCCN GTNACNTAYGARCCNCAYAGYCAR---GGNTCNGTNGTNGGNMGNMGNYTNGARAAYYTN ATHYTNGCNGAYGAYACNAAYACNAAYACNACNGCNMGNCCNCCNGCNCAYACNAAYAGY TTYAAYAAYGGNAAYTCNCCNTCNCAYACNACNCCNGAYAARCCNGTNYTNAGYCCNCCN CCNCCNAGYACNMGNCCNAGYMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGGGNAARTCNAGYGGNAARGGN AAYAAYMGNTGYTCNTGYGGNTCNMGNMGNTCNAAYAARTCNTTYGARGTNTGYCCNAAR TGYAGYAARACNAARAARAGYGCNGCNCARGTNGCNGCNTCNGCNGARGTNAARYTNGAY AARAARTCNTCNGTNAGYGGNMGNATGGAYTCNAARCAYTTYTCNTCNMGNTCNACNACN GAYAAYYTNCCNAGYTCNYTNAGYACNCCNGGNGARMGNGCNGGNYTNTCNTCNGCN--- ---ACNGCNGTNGAYACNTCNGTNGTNACNTCNTCN------AAYCCNAAYACNATGTCN CCNCAYYTNCCNAGYACNTGYGGNGGNCCNTCNGAYATHACNTCNCAYTCNACNAAYCCN CCNCCNGCNGARGCNGARGGNGAYACNMGNYTNCCNCCNGAYGCNAARGAYTCNGAYTCN TCNYTNTCNACNACNAGYGAYCCNYTNTAYGAYCCNAARTGYGAYTCNTCNAAYTCNTGY TCNAGYYTNTCNAGYTCNYTNTCNGCNGTNATHTCNTCNAARGGNCAYAAYGAYGAYTAY TGYGTNTCNGAYTTYCARGGNAAYGGNATHTCN--------------------------- ------AGYACNGAYAAYCARGGNYTNTCNCARACNGCNAARAGYTCNATHAAYTCNTCN GTNACNAGYAAYAAYGCNCCNAGYGTNTGYATHGAYACNACNGTNGAYACNGCNAARTCN GTNGCNTCNTCNAGYTCNAAYAAYATHTCNTCNGCNAAYGARMGNCCNGAYGAYCARGGN YTNTGYTCNACNACNCARAAYGCNAARTCNMGNCCNTCNGGNTCNAGYGTNYTNAARGAY TCNAARCCNTCNGTNGARGAYGARTCNCCNCARTCNCCNACNTCNMGNGGNGTNAARMGN ACNCAYAARGARATGGAYGARCCNAAYGARGCNTCNTCNTCNCCNAARCCNTCNCCNCAR AARAAYAARAARMGNTGYTTYATHTGYAGYTGYAARYTNGARYTNGCNCARMGNACNATH GGNAARTGYMGNTGYGARMGNGTNTTYTGYCCNATGCAYMGNYTNCCNGARYTNCAYGAY TGYGARTTYAAYCAYAARGARGAYGGNMGNMGNGARGCNMGNGARAARATGGTNAARCCN ACNMGNCAYATGGGNACNTCNTTYMGNMGNGAYYTNTGYGAYMGNGARGTNGAYYTNAAY ATHCARTCNGCNAGYGARAARAARGTNMGNTAYGGNMGNGGNCCNTAYGTNGTNAAYGGN GTNCCNATHGCNCCNGAYATHGARGGNTGYTGYAAYAARGAYCCNTGYGAYTGYMGNTCN GAYGTNATHTTYTAYGAYGGNAARGCNTAYGAYCARAARCCNTTYATHCARGGNAAYYTN MGNACNMGNCCNGGNAAYGTNATGTAYTTYGARGGNAARATGGTNGGNCCNTTYAAYCCN GGNAARTCNCCNYTNAARTTYGGNACNACNMGNAAYAGYATGAARCARCCNCARTCNCAR TGYTTYAGYAAYYTNAARATGGGNMGNCAYYTNCAYCCNTGYTGYACNTCNTCNATHTAY GGNGAYACNGCNCCNCCNTTYAGYAAYACNCCNAARYTNGCNTAYACNAARMGNGGNYTN CCNCAYGGNAARACNATHGGNTAYTTYMGNYTNAARGARGAYCCNGTNTGYTAYGARAAY MGNAARCCNGTNCARMGNATHGAYGAYTGYTGYTTYTGYGARCCNTAYGARTAYGAYGCN AGYCAYTAYYTNMGNGAYGARTGYCCNGGNAARATHTGYTGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNCARCARCARMGNAARYTNGARGAY AARYTNATGTCNTTYGCNCARACNTGGATGACNAAYATHYTNCCNAAYTGGGARTCNATG AARCARACNAARAARGTNMGNGARYTNTGGTGGYTNGGNYTNCCNTCNAAYATHMGNGGN ATHCARACNGTNAARATGTCNGGNATHACNTGYYTNTCNTGYAAYGTNGGNTTYGARGAY TTYGARYTNGGNMGNATHCAYTAYAARACNGAYTGGCAYMGNTAYAAYYTNAARMGNAAR GTNGCNAAYYTNCCNCCNYTNACNYTNGARAARTTYGARGARMGNCARAARGCNCARGAR ------CARCAR---GAYTCNACNGCNGTNCCNGARAGYTGYTAYTGYCARCCNTGYAAY AARTCNTTYAGYTCNTCNAAYTCNTAYGARAAYCAYYTNCARTCNAARAARCAYAARGAY GTNATHYTNACNCAYGGNAARTCNAARAARGCNAARAARAARMGNAGYGGNCCNCARCAY GCNAGYAGYACNAAR---------------GAYGARCARGAYGAYGARGARATGCCNTGY GARGARGAYGAYTCNGAYGTNGARTCNATGGAYAGYTAYGAYGCNAAYATHYTNGGNATH GARGTNTGYYTNTTYTGYTCNTTYGTNAGYCCNTCNATGGARGAYAGYYTNGCNCAYATG ACNGCNGARCAYGGNTTYTTYYTNCCNGAYGCNGARTTYATHTGYGAYYTNGARGGNYTN ATHTCNTAYYTNGGNGARAARGTNGGNGCNGGNAAYGTNTGYATHTGGTGYAAYGAYACN GGNAARACNTTYCAYAGYTGYACNAAYGTNCARMGNCAYATGATGGAYAARGGNCAYTGY AARATHCARCAYGTNGCNCARACNYTNTAYGARTTYGCNGAYTTYTAYGAYTAYTCNAAR AGYTAYCCN------GAYGCNGAYAAYAGYGARACNAAYTCNGCN---GAYTCNGTNGAY ATHGAYGARYTNGAYGGNGAYGGNTAYTCNYTNACNYTNCCNTCNGGNGCNATHATHGGN CAYMGNTCNYTNGCNMGNTAYTAYAGYCARAAYYTNGTNCCNTCNATGCARGARAARACN AARAARATGYTNCCNAARATGYTNGCNCARTAYAARGCNYTNGGNTGGGARGGNGCNACN GTNTCNCARGTNGARAARMGNGCNAARGAYYTNCAYTTYATGCARMGNCAYMGNAAYMGN CAYTTYATGMGNYTNGGNGTNAARGCNAAYAARTTYMGNTTYMGNTTYMGNGAYCARAAY GTNACNAGYYTNGAYYTNTCNYTNACNTCNCCNTCNMGNGAYATHGTNGAYGCNGCNTCN GTNGCNAGYCAYAAYAARGARATHYTNYTNAGYTGYYTNTTYATGGARGGNGTNGGNAAR TTYGCNYTNGTNYTNGGNGARAARTTYGGNGTNCAYYTNATHCARACNYTNTAYCCNYTN GTNGARAAYYTNGGNCAYCCNAAYATHCAYATHAGYAGYACNGCNTAYYTNGTNYTNACN CARATHTGYGARGCNTGYCARTAYMGNTCNATHGAYACNYTNATHCARACNAAYGCNGAY TAYYTNATHAAYAGYGTNTCNYTNMGNYTNMGNCAYTTYAGYCARAAYMGNMGNACNCCN MGNYTNYTNTGYGTNATGYTNAARTAYTGYTCNATGGAYATHYTNCCNYTNGTNGAYCAY AGYATHGGNGARATHYTNGAYACNYTNGAYGAYCAYTAYACNCARGAYYTNGTNYTNTTY ATGCCNGTNYTNYTNGARYTNACNTCNGCNATHGGNMGNTGGTTYCCNGCNACNATHCCN GCNAARAAYAARAAY------CCNAARCAYGAYGARGAYGCNTCNTCNYTNTCNATHGCN TCNTGYYTNGARGAYTAYGTNMGNYTNAARGCNYTNGCNGAR---GGNGAYTGGGGNGAY GARGARGGNCARGGNGARGCNACN---------------YTNGGNGAYATHGARGARGAY TTYGARAARYTNMGNGARGARMGNAARMGNGARAARGARGCNGARGARGCN--------- ATGGARGARGAYGGNGARGARGARGAYGAYGGNCARAARGARTGYCCNMGNCAYATHCAR GTNGTNAARGARGTNTTYGCNMGNATHAARAAYYTNYTNTCNTCNCAYGAYGCNMGNGTN MGNGTNCARTCNYTNGARATHGTNGCNCARGGNTGYMGNGAYYTNGCNGGNCAYGARMGN GARYTNYTNCCNCARATHCAYCARGTNTGGCCNGGNTTYTAYCCNMGNTTYCAYAGYGAR GARAARTTYGTNGTNATHAARGCNYTNCAYACNYTNMGNGTNATGGCNGAYACNGCNGGN AAYTTYATHYTNCAYMGNGTNACNAARGAYGTNYTNCCNGGNYTNGCNCARTTYATGGAR AARCARGCNAGYATHAGYTGYGARAGYMGNTCNAGYTAYGTNAAYACNTCNAGYTTYAAR YTNCARYTNGCNATHYTNGARGTNYTNGGNCCNYTNGCNGARACNYTNAARYTNGAYGGN AAYAAYYTNGAYGCNGTNGCNAARATHTGYYTNCCNTAYYTNAGYCAYYTNCARCCNGAR AARYTNCARAARGCNAGYGTNTCNGCNTTYTCNTCNTTYGTNCAYYTNGAYTCNGAYGCN GTNTGGYTNYTNYTNTGYMGNGCNTAYTGYCCNTGYMGNTAYGAYGTNCCNGGNACNGAR TTYGCNCCNYTN------------------------------------------------ ---------------CARGCNGGNATGGCNTTYGCNGGNGGNGGNCCNGTNTTYCCNCAR AAYCARMGNGGNGGNACNTAYGGNATGCCNGCNTTYCAYATGAAYTAYTCNCARCARGCN TCNATGCCNCCNATGTCNGGNYTNCCNACNGGNTCNTTYMGNAGYMGNTTYAGYGAYTTY CCNTCNGAYCARAGYCCNCAYYTNCCNATGCCNATHCCNTCNCCNGCNTCNGGNATGATG GCNGAYMGNYTNCCNAGYTTYAGYACNATHGTNTCNAGYGGNGGNGGNACNGARYTNTCN AARAGYAGY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AGYCCNAAYAARGARGARAAR---GTNAARAARATHCCNAAR MGNGCNCCNACNGCNTAYATGYTNTTYTGYAAYACNCAYMGNCCNACNATHGTNGCNGAR AAYCCNGGNATHGARTTYGCNAGYATHAGYMGNAARYTNGGNGARYTNTGGCARATGCAR TCNAAYAARCARAARYTNCARTGGMGNMGNAARGCNCARMGNMGNATGAARAARTCNAAY YTNATHTCNACNGGNAARGTN---GGNAARGARTCNCARGGNGGNGCNGGNGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GGNGCNCCNCCNCCNCARGGNTAYGGNGCNCCNCCNCCNCARGGNTAY GGNTAYGGNCARTGGCARGGNCARGCNTCN---TAYCCNCARCARCCNTAY--------- ---TAYCARGGNCARCCN------CARCARTAYCCNCARCARGTNGTNTAYATHGARGAY MGNCARAARAAY---------GAYAAYTCNGCNCARAAYTGYTGYATHGTNGCNYTNTGY AGYGCNYTNYTNTGYTGYTGYYTNATGGAYATGGCNGAYAGYAAYYTNCCNMGNCARGAY TTYGCNCCNCCNTGGYTNAARTTYCCNTCNGAYACNGTNAARTCNTCNAAYCARAARCCN AAYGCNTAYCARGGNGARMGNAAYMGNCCNMGNMGNGARGAYCCNTAYTAYTCNMGNTCN GAYTTYAAYMGNYTNCAYMGNCARAGYTCNTTYGAYTTYCAYGARGGNAARMGNTTYCCN CCNGGNCCNAAYAARTAYMGNCAYCAYTCNGTNGAYGAYGAYTTYGGNGGNTAYTCNTAY GGNTAYGGNTAYTAYGCNGCNAAYTAYAAYTAYGARAARTAYGGNATGCAYTTYAGYTCN CARCCNTCNYTNGCNMGNTCNACNAGYMGNGAYGCNAARTTYCCNCCNGGNMGNATHAAY CARATGAAYGGNAAYGCNATHYTNAAYGGNCCNCAYGAYYTNTTYGARCCNTAYTAYCAR CARGGNTCNAARMGNGGNTAYMGNGARMGNGAYTCNCAYMGNGAYGTNMGNAAYGGNGAY GGNAARGAYAARGAYAARGTNTCNGARAARGAYMGNCCNTTYACNGAYGAYTTYCCNTCN YTNAAYGGNTCNGGNGARGCNGTNGCNGAYTCNAARACNAARCCNGGNTCNGGNGTNTGG GARAAYCCNCCNAAR---TCNGCNAGYAARAAYGARGARTCNGCNGAYYTNYTNAARAAY TCNTCNCCNGGNATHTAYAARGCNYTNGTNCCNAGYAARAAYAAYCARGCNAARAARCCN ATHAARGARGTNACNMGNGTNAAYGGNAGYGTNMGNGARATHTCNCCNYTNAGYCCNTCN AAYAARTCNAGYCAYAARGARGGNTCNMGNTAYAGYCCNACNCCNGAYYTNGCNATHGTN ACNCARCCNAARAARYTNGGNGAYAARAARAGYGAYTTYYTNMGNGCNATHMGNAAYGAR AGYTCNATHMGNAAYGGNGAYAAYTTYCARAAYCARAAYCARAAYCARGAYTGYAARCAR GAYATHGAYGTNAAYGGNAARGARACNATHCCNGARTAYAGYCARAAYGGNGARMGNGAR GTNGAYACNAAY------GARAAY---------------GTNGTNAGYGGNAARAAYGGN YTNAAYGGNGARACNACNGARAAYTAYATHAAYGGNGAY---------GTNYTNATHAAY TAYGTNGAYCAYATHACNYTNTCNGGNGARGARGARGARMGNMGNYTNYTNYTNTCNATG GGNTGGGARGARGARGAYAARACNGARTAYGTNATHACNGARGAYGARATHMGNGARTTY CARAAYYTNGTNCARAAYCAYTGYCAYGGNCARAARAAYGGNYTNAARTCNTCNYTNMGN AGYGCNMGNGAYMGNAARATHGGNGCNATHAGYGTN------YTNAAYGGNATHCCNTCN GARGARGARAAR---------------ATGTCNCARAARACNTAYAGYTCNGGNTCNGCN TTYCCNGARYTNAARAARGGNACNYTNMGNYTNTAYAGYTCNMGNATHTGYCCNTAYGCN GARMGNGCNMGNYTNGTNYTNGCNCAYAARAAYATHCCNCAYGARGTNATHAAYATHAAY YTNAARGAYAARCCNGARTGGTTYGTNGAYAARACN---YTNGGNAARGTNCCNGTNYTN CARATHGAYGAYAARATHGTNTGYGARTCNACNGCNGTNAGYGARTAYYTNGAYGAYGCN TAYCCNGGNGAYAARYTNCARACNGAYGAYGCNTAYGAYAARGCNCARAAYMGNGTNYTN YTNGARTAYTTYGGNCARYTNTCNTCNGCNATGTAYGGNGTNMGNATGGCNGCNGAYGTN GARGARAARATGAARCARYTNTCNAARCAYTTYYTNTTYTAYGARCAYGCNYTNGCNAAR MGNGGNAARGCNTAYTTYGGNGGNGCNAARCCNGGNATGATHGAYTTYTTYYTNTGGCCN CAYATGGARMGNGTNCCNGCN---TCNAARATGTTYCCNAAR------ATHAGYYTNTCN GAYTAYCCNYTNYTNACNGCNTGGTGGAAYGTNATGGTNGCNGTNCCNGCNGTNAARAAR GARATGTTYGAYGCNGAYTGGCAYATGCAYGTNTAYACNYTNTCNAARGARGGNAARAAY TCNGGNGAYTAYGGNYTNTTYGGNMGNTAYCCNCAYGARTAYAAYCCNAARGTNCAYGGN CCNTAYATGCCNGGNMGNTTYTAYGGNAARCCNGAYACNGCNTTYGGNGARGTNAARYTN GGNGARYTNGGNTCNTGGTTYGGNMGNMGNAAYAARAGYCCNCARGCNGCNTGGGGNGCN GTNCAYMGNTCNTAYTGGMGNTGGGCNGCNAARAAYYTNCAYGTNMGNCARTCNGGNTTY GTNCCNTTYGGNCARGCNGCNATGGTNYTNTCNATHACNTTYTTYGCNYTNYTNTAYAAR GARMGNAGYYTNCARCARGARYTNTGYGARGTNMGNGAYGARGCNGARTCNACNCARGGN GARYTNGCNGAYAGYMGNMGNAAYGGNGCNGARYTNAARGCNGCNATHTGYGAYYTNGAR GAYGAYYTNAAYAARTAYAARCAYYTNCARGAYGARAGYACNACNGARATHTGYYTNAAR AAYGGNCARYTNAARGAYCARGARTCNGTNYTNTCNGARACNMGNCARCARYTNGTNATH GCNCARAGYCARYTNGARGTNTCNAAYGARGARACNGARAAYYTNGAYGCNGCNYTNACN GGNYTNAARCARAARTAYAGYCARGCNACNACNCARATHGGNCAYYTNGARGCNACNGTN AAYACNYTNCARGAYAARYTNACNGARAGYMGNAGYMGNGARATHGAYAARGARCARACN GTNGARCARYTNAARGCNGARYTNGARGGNYTNGAYMGNGCNTAYTCNGAYAGYAARGAY GARYTNAGYAARTGYGARGAYATGATHCAYCARYTNACNACNGARYTNGAYTCNGCNCAR AARGARATHAGYTCNTCNCAYAARMGNATHMGNGAYYTNGARGAYGGNAAYMGNGARYTN AARAGYCARGTNCARAAYGCNCARCAYGARGCNYTNCARAAYGAYGARMGNGCNCAYAAY TTYGARAAYAARYTNYTNTCNTAYCARGGNGARCAYACNCAYTCNGAYMGNGARTTYYTN CARAARGARGARCARATHAAYTCNYTNGARTAYCARYTNGARGARGCNMGNAGYGAYYTN GAYACNAARYTNTCNACNATHGAYCARYTNAARGCNGAYYTNACNATHACNCARTCNGAY YTNTCNCARGCNCARCARGAYAARAGYGCNGCNYTNAARGARATHGAYMGNYTNGARCAR CARGGNCARCARYTNCARYTNAAYYTNGCNTCNTCNCAYCARMGNCAYAARAGYGARACN TGYMGNTTYGARGARCARATHTCNTCNYTNGARMGNCARGTNTCNGARACNCARGTNGCN YTNMGNAGYGCNGARTGYGARACNAAYAAYAARGARGARCARATHAARMGNAAYGARGCN GARATHYTNTCNTGYMGNGAYGAYATHMGNAGYAARGTNGARGARATHGARMGNYTNGAR MGNTCNYTNCAYGARGTNMGNYTNGARATGAGYCARACNAAYGCNCARTGYAARCARYTN GARTCNGTNATHGGNGARYTNMGNTCNGAYGGNGARAGYATGMGNAARGAYYTNACNGAY GCNMGNATGCARTAYAARGAYTGYGCNCARGARYTNGCNCAYCAYGARGARAARYTNACN YTNATGGARCARAGYYTNCARTCNACNCARGAYCARYTNAGYCARMGNGTNACNGARATH GTNMGNCAYGARCARAAYTCNMGNAARYTNCARGCNGARYTNAARGCNGTNAARGARMGN GCNGARGGNTAYGARGARGARATGGARGAYCARMGNGTNATGATHGAYAARYTNMGNAAR GAYYTNGTNGARACNAARGARGARTAYCAYGGNTCNGTNCARGARGGNATHGCNTAYAAR CARCARGCNCAYAARAAYGARYTNGARYTNTCNGGNAGYMGNGARCARGARAARATGYTN TCNGAYCARGTNGARCARCARGARCARATHYTNAAYCARYTNCARACNGARYTNMGNGCN GARMGNGARMGNCAYGGNGAYACNGTNAARCARYTNAGYGCNAGYAARAARAAYGGNYTN GAYYTNCARTCNGAYYTNGARGCNTTYCARAARCARGCNMGNGARYTNCARGAYMGNGTN AARGCNMGNGARGARCARATGGTNMGNYTNMGNCAYGARATHGAYAAYYTNCAYCARAAR AAYMGNGARAGYAAYGARYTNATGGCNGARAARGAYGGNCARYTNMGNYTNGCNGARATG AAYYTNCARACNGCNCARAARCARGCNAARCAYCAYGCNCARGARATHGGNMGNTAYGAR GAYACNYTNGCNCARYTNCARACNGAYCARGARAARYTNCARGARCARTAYMGNCARTCN TCNTCNAAYYTNATGGARGCNGAYAGYAARGTNCAYGARYTNAARGTNCARYTNGCNACN YTNCARGGNCAYCAYAARGARGCNATGGARCARYTNACNGAYMGNACNMGNCARYTNGCN GGNATHAARACNGARGCNGCNAARATGGCNCARCARAAYAAYTCNATGAARGARGARATH ATGATHTAYGAYGAYAARGTNMGNAARYTNCARCARCARYTNMGNAARTCNCARGARATH AAYAARGCNACNGARGARGARYTNCARCAYTTYGARGARMGNTAYACNAGYYTNCARGTN GAYYTNGTNACNAGYCARGARAARCARAARCAYTCNYTNCARGARYTNTCNTCNAAYGAR GARGARATGGTNGTNGTNAARGTNGARYTNAGYTCNYTNCARGARAARTAYAARGCNGTN AAYGAYGARGTNCARAARYTNACNAAYGARYTNGARYTNACNAARCARAAYTAYMGNAGY GCNACNGARGARATHTCNGGNYTNMGNGTNGCNYTNGARGARTCNMGNGCNAAYGGNGAY MGNYTNCAYMGNGARAGYGARYTNGTNGTNCAYAAYGTNAAYACNTGGGTNCARGARCAR AARYTNGCNAAYGARAARYTNGGNAAYAARATHMGNGAYCARAGYAARTCNATHATGGTN YTNACNTCNGARAARGARGCNTAYYTNGAYCARATHACNAARYTNCARAARATHAAYAGY MGNACNMGNATHGAYYTNGARGAYAARACNGTNGARGGNGARAARYTNMGNGCNYTNCAR TCNCAYTCNGTNCAYCARCARGTNATHYTNAAYCARYTNAARAGYMGNYTNGARGARCAY GARYTNGAYAARGAYTCNGAYYTNAARACNAARGTNGCNGCNATHGARGAYYTNCAYCAY MGNYTNAARTCNAAYATHGARAGYATHCAYCARYTNAAYCARCARYTNAGYACNYTNCAR AARGAYAAYATHMGNATGMGNAGYGARYTNGAYMGNGARGTNGCNACNMGNCARGCNYTN GARATGCARATHCARGGNAARGAYCARYTNGTNGARAGYYTNMGNACNCARYTNGAYTCN AAYGCNTAYAARCAYYTNYTNGARAARGCNGARACNTAYAARGAYCCNGARAARYTNGCN MGNACNAAYATHAGYAARACNCCNGARGAY---ATH---YTNGAYCCNCAYAAYYTNGAY AARTCNTAYTGGGTNCARMGNGTNGGNGAR------YTNTCNATHCARYTNCARCARAGY AGYGARTAYTGGTCNGAYAARGTNMGNGAYYTNTCNGGNCARYTNGARAARGCNMGNACN GCNTCNACNACNYTNAAYTAYYTNYTNAARGGNGTNGAYCAYGAYGARGARATGCARAAR GTNGTNTCNGTNYTNGARAAYGTNGARAARYTNAARGGNACNCARYTNTCNGARAARGAR GAYATHMGNTGYYTNATHGARACNAAYGGNYTNGTNGARAARCARATHCCNACNCAYTTY TTYAARATHMGNGARGTNTTYGARGGNYTNATGGGNCAYATGTCNYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GARAARCARGCNAARACNYTNGCNGARMGNGTNTCNATHYTN MGNMGNGARAARGARGTNATHTAYMGNAARATHCARGARGTN---CARGARATGGARYTN TCNMGNCARMGNGARCARYTNCAYCAYCAYMGNCARYTNCAYAGYCARMGNAARGARGAR YTNYTNGARACNYTNCAYGAYYTNAARGARAARYTNGARGARCARAGYMGNAARYTNCAY ATGGCNTCNACNTCNCCNAARCCNAARAARAGYATHYTNAARAGYTCNAAYAGYATHGAY CAYAGYAARAARGARYTNGARTGGGAYGARATGAAYATHYTNGCNACNCAYCAYCCNCCN GAYAARGAYTAYGGNTTYATGAARGTNGAYGARCCNCCNACNCCNTAYAAYMGNGCNTCN ATHTCNGAYGGNGARGAYGARGGNGGNTCN---GGNMGNAARGGNAGYYTNGAYTCNGGN ACNGGNGTNGAYGCNGGNGAYYTNGCNGCNMGNYTNAARTCNGAYGCNATHGAYGAYAGY MGNAARMGNTTYGCNGAYGAYGAYGAYGAYGAYGARGARGAYTCNGARAAYYTNACNGAR GARGARMGNGCNMGNMGNAARTCNTTYATGACNAARMGNAARATGCAYTAYAAYGARTTY CARGCNGTNCARATGGCNAARAARYTNATGGCN------CARGAYGAYGAYGARGAYGAY GAYGARATGGAYACNMGNMGNGCNGGNGAYATGMGNATHAAYTTYGTNGAYATHGGNGAR ACNATHGCNCARMGNMGNMGNMGNTCNGGNGTNATHCARACNTGY---GGNCCNCCNCCN GARMGNMGNAGYACNATHAGYAGYGARATG---ACNAGYAGYTAYCARGTNACNMGNATG MGNAAYYTNTCNGGNGGNAGYAGYGGNAGYACNGCNAGYGGNAGYAGYAGYGGNAGYTCN ACNCARTTYGAYAAYCARTAYTCN------ACNGAYAAYTCNATGTAYTTYTCNATGGAY ATHTCNCCNTTYGCN---AAYTCNTCNGCNGTNCCNCARCCNMGN------GGNGAYTCN TCNTCNCAYMGNAARYTNGAYMGNAGYYTNAGYGAYGGNGAYAGYAGYAAY--------- ------ACNCARTCNCARMGNTCNGTNAAYTCNAGYMGNTAYAARACNGARYTNTGYMGN CCNTTYGARGARAGYGGNTCNTGYAARTAYGGNGAYAARTGYCARTTYGCNCAYGGNATG CAYGARYTNMGNAAYYTNGCNMGNCAYCCNAARTAYAARACNGARTTYTGYMGNACNTTY CAYACNATHGGNTTYTGYCCNTAYGGNCCNMGNTGYCAYTTYATHCAYGARGAYGAY--- ---------------------------------------------AARACNGAYGGNACN ACNAARGARACNAGYGGNAGYAGYAGYCCNTCNYTNAGYCCNACNGGNAGYGAYCAYGAY ------ACNTTYTCNTAY------------------------TCNGARTCNAAYAAYGTN GAYAAYACNMGNGTNAAYAAYTCNYTNACNGTNAAYATHAAYAAYACNTTYGGNAAYGTN GAYGTNCARTCNYTNGAR---CARMGNTTYGAYTCNGCNYTNAAYYTNAAYGCNMGNAAY GCNTAYAAYAAYTCNACNACNACNTGY--------------------------------- ------AARTCNTCNGAYGARTAYGAYATHTTYAGYTGYATHTCNGTNTTYAAYCCNGAR GARGTNGTNGTNGAYAAYGCNCCNMGN---CCNTCNAAYACNYTNTCNTAYCCNAARCAR CARCARCARCCNYTNGAYAAYTGYCCNACNTAYGTNGAYACNTCNTGYTTYTGGCCNTCN ------AAYGTNTCNTCNCARGGNYTNGCNCCNGTNGAYCCNTTYCAYTAYTCNCCNACN GGNTCNACNGGNTCN------------------------GAYTCNGGNAGYAGYGAYTGY AGYGGNAGYACNGARAGYYTNGCNAGYTCNGGNTAYMGNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------ATGTTY MGNAAYTTYTCNTCNACNGCNTGYGCNYTNGCNGTNGGNGCNAARAARAAYYTNGAYGGN GGNTTYGGNGAYTCNGTNCCNTCNGCNAAYACNTCNTGYYTNGARMGNTGYYTNYTNAAR GTNGARGARGCNGAYTCNTGYGTNTAYGTNGGNGAYMGNATHAARAARGCNGTNGGNTTY CCNCARYTNACNGCNTGYTGYAARCCNYTNMGNTAYAARGAYTTYATHATHAGYTAYGAY ACNAARAAYMGNATHCCNAAYTGGGTNTAYGARCAYYTNCAYMGNTGYAARYTNTTYAAR GAYGAYCCNTGYGAYAARMGNCARACNYTNTGYCCNAAYGARAAY---GARAARCCNAAR TTYCAYCCNGAYTGYMGNATHCAYGGNTAYCAYMGNGCNGAYGTNAARGAYTAYTGYGAY TCNGAYTAYGARYTNGGNYTNATGGCNGAYCCNGCNAAYTAYCCNTTYGAYTGYGARGCN TGYGCNGARACNCARGTNATGACNAAYGTNGTNCCNATHGTNCCNGGNTTYAGYTGYGGN CCNTGGTTYGARYTNCARTGYTAYATHMGNGARACNYTNGTNAARGAYAAYAARAGYGTN TAYGTNTGYTCNGGNCCNYTNTTYYTNCCNGARGAYCARCARCCNACNAARTGYATGAAR TTYGAYGTNYTNGGNGARGGNGARGTNTCNGTNCCNACNCAYTTYTTYAARGTNATHATH ATHGARACNYTNGAYGGNAAYYTNGARYTNGARTCNTAYATGATGCCNAAY--------- AARGARYTNGAYGAYAAYAAYYTNGAYAARTAYYTNACNCCNYTNTGYAARATHGARCAY TAYTCNGGNYTNATHTTYTTYCCNGARAARAARGTNTGYTTYACNAGYAAYAAYAARMGN MGNGGNGCNATGYTNCAYGCNYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AGYCCNMGNGGNACNGTNMGNGGNTTYAARAAYMGNGTNMGNGCNGGNATHGCNACNTTY GTNACNTCNATHGARGAR---------TAYYTNACNGARGARAARGGNAARATHGTNTTY TAYTCNACNMGNATHCARATHATHMGNGARACNTAYGARAARTGYAARACNGTNMGNAAY ATHYTNCARACNCAYATGGTNMGNTAYGARGARAARGAYYTNTGYYTNAAYGGNGARATH CARAARGARYTNAARGARMGNYTN---------GGNATHGAYGARATHGARYTNCCNCAR GTNTTYGTNGAYGGNACNYTNYTNGGNAAYGGNGARACNATHCARTAYYTNAAYGARACN GGNGARYTNMGNMGNATHTTYAARCAYTTYCAYAARGTNMGNGTNMGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARTTYGARAARYTNGARMGNYTNTTYGTNATHAAYAAR---TCNYTNGAYACNTTYTAY MGNCCNYTNGGNATHYTNYTNCAYGGNCCNCCNGGNTGYGGNAARACNTCNTTYGGNAAR AGYYTNGCNAARAARTGYGGNGCNGCNTTYTAYAAYATHGARGCNTCNTCNYTNYTNATH TCNGAYTTYGGNGCNGGNGCNGCNGCNYTNAARTCNTCNTTYAARAARGCNATHGAYYTN ACNGAYGARGGNCCNGTNATHYTNTTYYTNGAYGARATHGAYACNATHTGYCCNMGNCCN GARACNGCNAGYATGGGNAAYAARCARYTNAGYAAYGCNYTNATGACNGARATGGAYTCN ATHCAYTGYAARAARATHTCNGGNYTNYTNGTNYTNGCNGCNACNAAYTCNGTNTCNAGY GTNGAYCCNCAYYTNMGNMGNCCNGGNMGNTTYGAYCARGARATHYTNATHAAYGTNCCN ACNGARACNCARMGNYTNTCNATHYTNACNATHYTNACNGCNGAYYTNCCNYTNAARCCN GAYGTNTCNTGYAARTCNYTNGCNGARMGNACNCCNGGNTTYGTNGGNGCNGAYYTNMGN AGYYTNTGYGARGARGCNGTNAGYCAYGCNCARTCNYTNCARGARTCNYTN--------- ---GCNGTNGGNATGAARGAYTTYGARTAYGCNYTNCAYAARACNACNCCNTCNYTNAAR AARGGNAGYGARTGYGTNGTNGAYYTNAARCCNGTNAAYTGGTCNGARATHGGNGGNYTN GARGAYGTNAARGCNGARATHCARCARTCNATHGARTGGCCNYTNAARTAYCCNGAYGTN YTNAARAARATGGAYATHCCNCCNGCNAARGGNATHYTNYTNTAYGGNCCNCCNGGNTGY TGYAARACNACNYTNGTNMGNGCNGCNGCNACNTCNTGYAAYGTNTCNTTYYTNTCNYTN AGYGGNGCNCARGTNTTYTCNGCNTAYGTNGGNGARTCNGARAARYTNATHTCNCARGCN TTYCARAARGCNMGNGCNYTNGCNCCNTCNATHYTNTTYTTYGAYGARATHGARTCNYTN GTNGGNAARMGNAARGCNGAYACNGGNAAYAAYMGNGTNCARGARMGNATHYTNTCNACN ATGYTNAAYGARATGGAYGGNATHGGNAAYMGNYTNGAYTTYAARYTNGARTCNTCNATH ------------TCNMGNACNGARAAYACNAAYACNAGYAAYCARGGNYTNCARAARACN YTNAAYGAYAAYYTNAGYCCNGAYGARATHCCNGTNYTNGAYCARCARCCNGGNGCNAGY GAYAAYYTNMGNGTNYTNYTNGTNGGNGCNACNAAYMGNCCNGAYATGYTNGAYGCNGCN ATHYTNMGNCCNGGNMGNYTNGAYAARCAYGTNTAYGTNCCNCCNCCNGAYGARCARGCN MGNAARACNATHYTNCARATHTAYACNTCNAARATGTCNTGYATGGAYGTNAAYYTNGAY YTNYTNGCNAAYMGNACNGARYTNTTYAGYGGNGCNGAYYTNAARAAYYTNTGYAARGAR GCNGGNYTNCARGCNGTNMGNGGNCARYTNGCNTCNCCNGAYGAYCARYTNGAYYTNACN GTNAGYCARCAYCAYTTYYTNCARGCNYTNGTNAARGTNAARCCNTCNYTNCARGARATH AAYAARYTNCARTTYGARYTNGARTAYMGNCARAGYACNYTNATGGARAGYCARCARACN TGGGCNCARMGNTTYGAYAGYGTNTGYCARGARAAYGTNTCNYTNGTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGAAYGTNTGGMGNAARATHMGNYTNGGNGTNAAYACNYTNTAY ACNAARCAYYTNTTYGTNACNAAYGTNGTNACNTGYGGNGGNYTNYTNGGNGTNGGNGAY TGYATGGTNCARCARATGGGNTTYATHTAYGAYAAR---GARGCNMGNTAYGAYTAYGCN MGNACNGGNMGNYTNATHGTNGTNGGNTTYTGYYTNGGNCCNTTYAAYCAYTAYTGGTAY AGYTTYYTNGAYAARGTNGTNAARGGNCARGGNATGAARYTNGTNGGNAARAARATHATH TGYGAYCARTTYGTNGCNGGNCCNTTYTTYTGYACNACNTTYYTNGCNGGNACNACNYTN YTNGARGGNCAYGGNGTNTCNGCNGCNGTNGCNGARTGYAARGCNAARTTYYTNCCNATH TAYATGGTNGAYTGGYTNTTYTGGCCNGCNGCNCARTTYATHAAYTTYMGNTTYYTNCCN AAYAARTAYMGNGTNYTNTAYGTNAGYTTYGCNACNYTNGTNTGGAAYTCNTTYYTNTCN TTYATGAARCAYMGNGAYATHYTNMGNAAYYTNACNGARGARYTNTTYCCNTGGYTNTAY AAYAARGARYTNYTNAARAAYAGYGTNCAYMGNTTYTGYACNAGYYTNAARACNGARCCN TGYTCNACNYTNTTYTAYYTNYTNYTNATGGTNTTYGGNTTYATHCCNTTYYTNTGYTTY TTYYTNTTYATHGGNGGNTCNTTYATHYTNACNATHGTNTGGTTYGCNGTNTGYCARGCN GTNGTNGTNACNGTNTCNGCNYTNATGTTYGGNGGNTTYATGGTNTTYYTNATHATHATG TGYTGYTCNATHGCNGGNGTNTTYGGNYTNATHATHCAYACNGTNTAYGGNTGG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------MGNAARGCNYTNGCNCAYGCNAGYGARACNCARGARGAYGAYCARACN GARGTNYTNAAYGTNATHGCNTCNYTNCAYATHAAYYTNATHCARMGNATHAARAARAAY MGNCAYYTNTCNCCNGAYCARATHGARGAYTAYATGAAYCARGCNAARCARGAYYTNCAR AAYGTNAARACNAARATGGAYGGNGARAARGARGCNCARGARGARGARATGTTYAARAAR YTNAGYAAYCARAARMGNAARTCNYTNGCNGARAARATHGCNGARCAYGGNAARGARYTN CARCARTAYATHAAYAARTCNAARGCNCARCARACNGARGGNCCNGTNGAYCCNGTNTCN TAYGTNGARGGNYTNGTNGAYYTNAARTCNMGNCARMGNAARGARYTNAAYACNYTNGAR AAYCARATHGAYMGNGAYCAYGCNCARCARYTNGARGAYYTNMGNGAYGARGTNGCNAAR AAYGCNATHAARGARYTNGARGGNGTNCARGGNGAYYTNGTNAARAGYYTNAARGARGAR GGNATHMGNGAYGAYGCNATHGARAARATGYTNCARAARCAYGAYCARACNYTNACNGAY YTNMGNCARMGNCARYTNAAYAAYMGNMGNAAYCARGARGCNAARYTNAARGAYGAR--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CARGTNATGGCNYTNCARMGNCCNYTNGARTCNGCNTCNGARTCN YTNGAYACNCARGCNMGNGARCARMGNTCNGAYATHYTNCCNATHGARGTNGARGAYGTN ACNMGNAARGCNGGNAGYGARTCNGGNATHATHCCNGGNMGNGTNGTNMGNMGNGCNAAR MGNCARGTNAGYAAYATGAGYAAY---------------AAYTCNGTNYTNTCNGAYGGN CCNAAYYTNYTNGCNGGNCARYTNGAYAARYTNAAYCARYTNGTNGAYMGNYTNGARTGY AARATHAARTTYGARAAYTTYMGNGAYGARGARGTNGTNACNTCNCARGAYGAYACNGTN YTNATGGTNCARMGNGARTTYGTNGTNAARGARGAYAARATGGAYGAYTTYMGNGCNCAR YTNMGNTCNTAYGTNGAYYTNACNYTNGGNTTYMGNGGNTGYTTYAAYGTNAGYGTNMGN GAYATHMGNCCNAGYCAYTCNTTYAGYGTNTAYGARGTNTGGMGNAAYGARGARYTNTAY YTNCARAAYTGYGGNAGYGARGCNACNACNTCNYTNGTNAAYAARACNGCNGARYTNYTN GARAARCCNGARACNGTNAARTGYATGACNATHCCNGGNGCNTGGTGGACNCARGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNTTYTCNTGYYTNGGNGTNATHYTNGTNTTY GTNGTNGTNTAYTAYTCNTGGAARAARTAYCARCAYMGNCARMGNATHYTNMGNATHTTY MGNCAYGARCARAAYGAYCCNTTYCARGCNYTNTAYAGYCCNAGYCARGAYTCNTAY--- ------------------GAYATHMGNACNTGYMGNTCNTAYGARMGNATGGAYAARATG GAYMGNYTNATGAGYCARCCNGAYGCNMGNYTNTGYGCNTCNACNCCNGGNATHTAYGTN CCNGAYAAYAARTTYCCNAGYCCNGTNMGNTCNGCNAAYACNAGYTCNGAYGAYAGYGAY CAYCAYCAYGTNGCNGCNAARGCNAGYMGNATGGTNGAYATGYTNACNGAYGARAAYMGN GCNYTNMGNGARGARYTNGCNACNGCNACNGTNAARGTNTCNMGNYTNYTNAARTTYGAR ATGGARGTNGARAARATGCAYGAYGCNCAYGARTCNYTNYTNCARTCNCAYCARAARMGN GARGCNYTNTGGYTNGCNATGMGNMGNAARYTNGARGARMGNGCNCARGCNYTNGARGCN YTNGCNGCNCCNGCNGGNGGNGARGGNGGNGAYTCNCARMGNGCNYTNTCNATGTCNGAR YTNGAYYTNMGNACNAARYTNGCNGARAARGAYTCNYTNATHGCNMGNYTNYTNGCNCAR AAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------TCNMGNCCNGCNAGYMGNTCNAGYYTNGAYAGYTAYGAYGARGARGARACNCAR AGYGARAGYAAYGAYGGNGGNTAYMGNCCN---GAYGAYGARAGYATGGAYGAYGAYGAY GAYGAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYTTYCARTCNTCNYTN ATHGGNACNCARGARCAYTGGGAYACNACNTAYCARAARGARYTNGARAAYTTYAARACN ATHGGNGAYGTNGGNGARATHTGGTTYGGNGARAAYACNCARGAYMGNATGGTNMGNTGG ATGACNAARAARTCNGGNYTNCCNACNACNGCNAGYYTNATHGAYYTNGGNTGYGGNAAY GGNATGYTNYTNGTNGCNYTNMGNGARGARGGNTTYATGAAYYTNACNGGNGTNGAYTAY TCNAARTAYTCNGTNGARYTNGCNGCNAARATHTCNGARTCNGARGGNATHAARGAYATH ACNTTYGARGARTGYGAYATHYTN------TCNGCNATGGARGCNCARAARMGNCAYAGY CAYTTYAAYGCNTGYYTNGAYAARGGNACNTAYGAYGCNATHAGYYTNAARAAYACNGAR GAYCCNACNGAYMGNAARACNTAYATHAGYCAYGTNCAYGCNATHYTNAARCCNCARGGN ATHYTNGTNYTNACNTCNTGYAAYTGGACNAARACNGARYTNGARAARCAYTTYTGYACN TAYTTYGAYYTNACNGAYGARATHCCNTCNCCNAARYTNTCNTTYGGNGGNAAYACNGGN CARACNGTNACNTCNYTNATHTTYACNMGNAARGTNCARATHATHGTNTTYCCNGARTAY GGNATHTAYGGNYTNTCNTTY---GAYMGNAARTCNATHTAYCCNTTYYTNGARCARATH CCNGAYCCNGARGTNACNTCNTGGTCNCCNTGYTCNGAYCCNACNMGNTTYCCNGAYACN GARGTNCARCAYGCNYTNAGYTGYATGGCNCARGANNNNNNNNNNTAYGTNGTNGCNNNN ATGGGNGAYMGNGTNNNNTGYNNNNNNTCNACNGAYCCNAARTGYCCNNNNGAYGGNCAY TAYCARTAYAAYACNGCNGTNGCNTAYGGNCCNGAYGGNACNYTNNNNGCNNNNTAYCAY AARNNNAAYYTNTTYNNNGARNNNGCNTTYNNNNNNCCNGARNNNAARGTNGTNTAYTTY GAYACNCCNTTYGGNMGNGTNGGNNNNYTNATHTGYTTYGAYYTNYTNTTYAARGANCCN GCNGTNNNNATGGTNACNGANNNNAAYNNNACNNNNNNNGCNTTYCCNACNGCNTGGNNN GAYNNNYTNCCNYTNYTNTCNGCNNNNGGNNNNCAYTCNTCNTTYGCNMGNGGNNNNGGN GTNAAYYTNYTNNNNGCNAAYNNNCAYNNNCCNNNNNNNNNNNNNCAYGGNAGYGGNATH NNNACNCCNNNNGGNNNNGCNAGYTTYTAYTAYNNNAGYGAYNNNNNNTCNCCNGGNNNN YTNYTNGTNTCNACNATHGAYGTN------CCNACNCCNTCNAAY--------------- ---CAYAAYCCNACN------GTNGGNATGATHCCNNNNCCNNNNCCNACNACNAGYTCN CAYYTNAGYCCNACNNNNCARMGNATGAARCAYMGNCARGAYGCNGCNAAYACNGCNAAY ACNATHGCNATHGGNATGAARACNAGYAAR------GAYGAYGARTTYNNNNNNNNNYTN TTYNNNGAYGARATGNNNACNTTYMGNYTNNNNNNNNNNTCNTCNGGNNNNNNNGAYNNN TGYCANNNNNNNGTNTGYTGYTCNYTNACNTAYNNNNNNGCNGAYNNNNNNNNNGAYNNN GAYNNNNNNGCNNNNGGNNNNTTYGAYGGNYTNCAYACNNNNNNNGGNCARTAYTAYYTN CARNNNTGYNNNYTNGTNAARTGYGCN---NNNNNNTAYGAYNNNNNNTCNTGYGGNNNN NNNACNNNNNNNNNNNNNACNAARTTYAARTCNTTYTCNYTNTCNGGNNNNNNNNNNACN NNNNNNGTNTAYCCNCARGTNNNNYTNNNNNNNGGNNNNCARYTNNNNNNNACNGAYGAR NNNGCNTGGAGYTTYCANNNNAAYACNNNNNNNGCNNNNGGNCCNGGNYTNGAYNNNNNN YTNYTNTCNGCNNNNYTNNNNGGNMGNNNNTAYNNNMGNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------TTYYTNACNACNTGYATHGCNTCNAAYACNMGNGARCCN ACNAARATGAAYGCNAAYTCNTCNATGACNATHCARGTNCAYGCNCCNCCNTCNGAYCCN CCNACNATHACNGCNGARCCNGAYGAYACNCCNYTNTCNAAYAGYGTNCAYGTN---GTN ATHYTNGGNGARCARTTYMGNGTNGTNTGYTCNGTNGARGGNGGNGCNCCNTCNMGNATG ACNATGGTNATHGARTGYGAYGGNGTNCARAAYGCNACNAGYACNGGNCCNAAYGTNACN YTNAGYGGN---GTNGTNACNAARCCNATGGAYGGNATGTTYTGYACNTGYTCNGGNAAR CAY------CCNTGYTAYCAYCARACNACNTCNTTYCCNTTYATHGTNGTNTAYGGNCCN ACNMGNYTNACN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------MGNTGYMGNAAR---------------GAYGGN TCNTGYMGNATHCARGTNGCNCCNCCNGTNGTNGGNCARGARGTNTTYGTNTCNGGNCAY GCNGTNTTYAGYACNGAYYTNGGNYTNGARCCNACNYTNTGYCARGGNGTNGTNTCNAAR GTNATHGARMGNAARGAYAARCCNGTNYTNYTNCARACNACNTGYGCNGTNCAYGCNGGN GTNAGYGGNGGNCCNGTNYTNACNGGNGAYGGNMGNYTNGTNGGNATHGCNGTNTGYAAY ACNMGNGAYTCNTCNAGYGARAGYAGYTTYCCNCAYGTNAAYYTNTGYGTNCCNGCNACN GCNGTNTGGCCNGCNATHCARTCNTTYYTNCAYACNCAYGAYAARAARTTYYTNCARGAR YTNCARGTNMGNGAYTGYGAYYTNCARGCNYTNTGGGCNYTNGGNACNMGNACNATGGCN GAYYTNTCNYTNGAYGAYATHATHAARCARAARAAYGTNAARGTNCARTTYMGNACNAAR CARCARCARCCNAARACNCARGTNCARGGNAARACNCCNGTN---------ATGAAYCCN AARTTYCARGCNAARAAYGTNCARMGNACNTTYGAYGCNMGNTCNAARYTNGGNCCNAAR AARATHGTNGAYGCNMGNAAYAARATHGTNACNAAYAARAGYAAYGGNAARGGNGAYGCN MGNAGYAARATHGTNCARAARCARGTNCARAARGGNACNTTYGAYGCNMGNTCNYTNYTN AARMGNCARGGNAARAARACN---------AAYGGNGCNGCNAAYAARCCNCARGGNCCN CAYAAYAAYAAYTTY---------CCNGCNATHCARCCNATHACNMGNACNYTNTCNAAY CCNGCNAGYYTNGGNCARTTY---GGNGARCCNYTNATHMGNCARATHCCNAAYACNGAR GTNTCNTTYTCNMGNAAYTCNYTNCARATHACNAARMGNGGNATGGGNMGNCCNTCNCCN GCNCCNYTNATGGGNGAYGCNGTNCCNATHATHCARATHMGNAAYGAYMGNTAYCARMGN CARGARATGCCNCCNCARCCNGCNTGGTCNGCNCCNACNCAYTCNGCNCARMGNYTNCCN ------CCNCARCCN---GCNCAYYTNGAYATGCARTAYTCNCAYCAYCCNTCNTCNTCN TCNTCNTAYCCNCCNACNTCNTCNCAYAAYTCNCAYTCNTAYCARGAYYTNGAYGAYCCN MGNTAYCAY---ACNGCNTCNAARGTNGTNCARGARATGCCNMGNATGCAYATHGCNAAY GTNAARGCNGTNGARGCNGCNGGNATGMGNCCNGTNTCNTCNMGNCCNGTNYTN------ ------------CARTCNMGNGCNCCNCCNGGNGCNGCNACNYTNTCN------------ ---------ATGGTNTCNGCNTCNCAYCCNATGGGNGGNAGYAGYYTNAARMGNMGN--- CARCCNGCNCARCARGAYGTNGGNGGNCCNYTNMGNYTNGGNMGNGGNGGNGGNCCNGGN ATHCARGTNGGNATHGGNGGNTCNTCNCCNCCNAARMGNATGAARGTNGGNGCNACNGCN ------ACNGARCCNATHGARATHACNGAYYTNGAYCARGAYAGYTCNTTYGTNAGYCCN YTNCARGGNTTYMGNGTNGTNGTNACNAAYYTNTTYCCNMGNGTNACNCARGARGAYATH ATHGARYTNTTYGGNGTNGTNGGNCCNYTNAARAARGCNMGNYTNYTNAARGCNGGNTCN TCNGARGTNGTNTAYACNACNAARGARGAYGCNGTNAARGCNGTNCARAARTAYCAYGGN MGNGARYTNGAYGGNCARCCNATGTAYGTNAARATGACNACNCCNTCNACNGCNGTNGTN AARGCNCCNCCNGGNGGN---GAYCCNGAYATHACNGGNGARGCNYTNMGNYTNTAYAAR AARCCNAGYAGYYTNGGNGCNYTNCCNGTNGCNCCNATHGARACNCCNACNATHCAYMGN GCNYTNTTYAARGTNGGNCCNCCNGCNCCNAAYAARTCNGTNAARTTYACNGTNAARATH GAYTTYGTNCCNMGNTTYGTNCARYTNGTNMGNGARTGYATHYTNACNCAYGARTGGACN AGYGTNYTNAARATHGTNAAYGCNYTNGTNAAYGARGGNAGYAARGCNACNGAYACNYTN TGGAARGCNGGNATGACNTCNYTNATHATGGARAARAARCCNCAYATHGTNGAYCARTTY GTNMGNCARYTNTAYAARYTNACNGGNYTNACNTGYGTNGARGTNYTNYTNGAYTAYYTN YTNTAYYTNYTNATGCAYGGNGAYYTNGAYMGNGCNAARGAYYTNAARCAYGAYCAYMGN AAR------TAYTAYYTNCAYGTNACNAARGARACNMGNGAYAAYGCNTCNGTNYTNTTY TTYGGNTAYYTNGGNYTNACNGARTAYATGMGNTGGAARGARGGNACNAAYGTNGCNGAY TGGAAY------GARGCNGGNTCNYTNAARAGYAARYTNTCNGARGGNTCNGTNGAYMGN YTNATGMGNTCNMGNGCNGAYGCNGCNYTNTAYTAYTTYTTYCARGTNMGNGAYAARTCN GGNGTNTGGGAYATHTTYATHGTNAARATGGTNGARATHTAYGARTAYTAYAAYGARGTN GCNAAYGCNMGNYTNYTNYTNGARGARTAYMGNCARACNAAYCCNACNAAYYTNAAYGCN CAYMGNTAYYTNTAYCARTTYTAYYTNMGNCAYYTNGGNCCNAAYGARGARAARATHTCN TGYYTNGARAGYATHGTNAARYTNGAYCCNTGYAAYCCNYTNGCNATHGAYYTNTTYAAR GARCARGARTCNYTNGAYCCNCARGCNATHGCNATHYTNTTYGAYTAYYTNGAYTTYGAY CAYTGYAARGAYGAYAGYCARACNTGGTCNTAYYTNCARATGGCNYTNAARGAYAARACN GARTAYGARGARGARYTNCARGTNGTNAARYTNTGYTGGCARACNMGNMGNGAYTGGTGG CCNYTNTCNAAYTGYTCNACNTTYGTNYTNATHGTNGGNYTNATHYTNAAYGTNGTNGAY AGYAARAARGCNCCNGARTGYTCNACNTGYAARGARATHGTNGAYGAYTTYCAYAARGGN YTNTCNGCNACNGARAARTCNAAYTAYGGNGGNGGNAAYACNAAYTGGGARGARAARTCN YTNGGNTCNTAYGCNTTYAGYGARGTNMGNYTNGTNGARATHATHGARAARYTNTGYCAY GAYAARTCNAAR---TGYCAYACNATGYTNGARGARCAYGARGARYTNGTNGARAGYTTY TGGTAYACNCARTAYGCNAARAARACNAAYAARGAYTTYTTYTCNTTYYTNTGYATHGAR AAYATHAARGCNTGYTGYCCNAAYAAYACNTAYGGNAARGAYTGYAGYCCNTGYCCNGGN GGNGCNGARMGNCCNTGYCARGGNAAYGGNAARTGYTCNGGNGARGGNACNMGNAARGGN ACNGGNAARTGYGTNTGYTCNTCNGGNTAYAARGGNGAYYTNTGYTCNGARTGYAARACN GGNCAYTAYGARGARAGYAARAAYGAYACNCAYACNGTNTGYMGNGTNTGYGAYATGTCN TGYAARGAYGGNTGYTCNGGNGARGGNCCNACNGCNTGYGARGARTGYAARGAYGGNTGG GTNGARGAYGCNAGYYTNGGNTGYAARGAYGTNAAYGARTGYYTNGARGARCCNTGYGAR GAYAAYCARTAYTGYACNAAYACNYTNGGNTCNCAYACNTGYTTYACNTGYGAYATHGCN TGYACNTCNTGYACNGGNGCNGGNCCNTCNAARTGYAAYGARTGYAARGARGGNTAYGAR CAYYTNGARGAYGGNAAR---TGYCARGAYAARGAYGARTGYAARYTNGAYTCNAGYYTN TGYTCNAARACNAAYGARGARTGYTTYAAYACNGARGGNGGNTAYGARTGYATHTGYTCN ACNGGNTAY---GARTAYAARGARGAYGARTGYGTNAARTCNCCNAARGAR--------- ---------------------------------------------------GGNAGYTCN GARAGYAARMGNAAR--------------------------------------------- ------ATHGTNGTNGARGAYGTNACNGGNGAYGGNGTNYTNCCNGARYTNCCNGARCAR GARTCNTCNGCNGAYAAYGARAAYTAY--------------------------------- ---------MGNTCNATGAARAARGARATHGARGARTTYTAYAAYGARAARYTNAAYGAY YTNCARAARMGNAGYGARGAYYTNCARCARCAYACNAAYGAYCARTTYGCNACNGCNGTN AARGARGTNGARCARAARTTYYTNAARTAYACNTCNTCNCCNGTNTGYCARGAYYTNCAR ACNAARGTNYTNGARTGYTAYCARTCNAARCCNGAYTCNATHYTNGAYTGYTCNCCNGTN GTNAAYGCNTTYTCNACNTGYGTNGAYMGNGCNMGNATGACNGTNTCNATGACNATGGAY AARAAYCARAAYATHGCNGCNAARGARGTNGARMGNTGYTCNAARYTNGGNACNCARMGN YTNCARGARGGNTTYCCNGARAARGCNYTNGARGCNTAYMGNAAYGCNTAYAARCAYGCN CARTCNYTNAGYCARTAYGGNTAYATGATHMGNGCNTGYGCNTTYAAYYTNGGNGCNATG YTNATHTCNATGGARAAYTTYATHGARGGNYTNGCNTAYYTNAAYAARGCNGTNCCNCCN GARGGNAARMGNGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARACNAAYYTNMGNGCNGARAARGCNTCNGTNCCNGARTAYYTNYTNTCN MGNAGYGTNGCNGGNACNACNGCNCCNGAYYTNATHGCNGGNATHAAYTCNYTNACNGAY GGNGCNATHTAYGGNMGNTTYTTYAGYTTYTAYCCNMGNMGNAARGTNGAYATHYTNMGN TGGYTNGGNTAYTGGATHAGYMGNGGNGCNGTNCCNYTNGTNACNYTNAAYYTNCARAAR GCNGTNCCNCCNGGNTGGGTNACNCCNGAYGCNTGGCAYCAYCARATGGTNTAYGGNGTN GGNCCNAARGGNGTNTAYYTNACNAAYCCNYTNGARATHGTNCCNGTNTCNATHATHGAR CARCARYTNTGYAGYGARTCNGTNYTNYTNGTNMGNMGNAGYGAYGTNYTNACNMGNTGG ACNGAYGAYTGYGAYYTNAGYCARYTNATHTGYGTNGARGAYCCNMGNTGGMGNGARATG AAYGTNYTNGGNCARGCNGTNAGYGTNYTNMGNGARGCNAAYACNCCNGGNTTYCARGGN TAYAARYTNCCNTGGACNTCNCAYATHTGYATHCCNGCNGTNTAYAARGCNGGNGTNAGY YTNTAYGTNAARMGNGAYTCNGARAGYTAYAARGARYTNGTNGCNYTNGARGARYTNCCN YTNAGYTGYGAYAGYYTNTCNGARGARGAYGARGAYGTNYTNGARGAYGARMGNYTNAAR AARCAYATHGAYCARGCNTCNAARTGYGGNTTYTCNGAYMGNCARATHAGYAAYGTNYTN CARMGNYTNGGNGTNACNTGYAGYATGGAYGAYATGATGMGNGARYTNGTN------AAR GARCCNCARGTNGTNGARGARGARAAYGAYGAYACNGGNMGNAGYGAYTCNATHAARGAR TCNGGNGGNAGYGTNMGNGARCAYGARGTNGAYGARGAYGARGARGARGAY--------- ------------TTYAAYGTNGAYGAYAGYAGYAAYYTNMGNCAYATHGTNATHGAYGGN AGYAAYGTNGCNATGAGYCAYGGNCARAARGTNTTYTCNTGYATGGGNATHAARATHGTN GTNGAYTGGTTYAARAARMGNGGNCAYCARAAYATHACNGTNTTYGTNCCNCARTGGMGN AARGARGCNTCNMGNCCNGAYGCNCCNATHTCNAAYCARGARATHYTNACNGARYTNGAR GARGARMGNGTNGTNGTNTTYACNCCNTCNMGNMGNGTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARGARCCNYTNAARGTNGCNGARAARTAYGTN GARYTNACNGARGARAAYTAYAARGAYATGGAYAAYATHYTNGTNGARGARATGYTNAAR GCNACNMGNGARAARGGNCARTCNAARYTNGARGTNAARTAYGTNGTNCARGTNTCNCCN YTNGARATHTCNGAYYTNGCNCARCCNTCNATHCARCARATHGTNATGYTNCAYCCNACN ACNACNYTNATHTTYAARCAYCARGCNATGAARTTYMGNAARAARAARGGNTTYGCNGAR GCNACNTTYTCNACNATGACNGARYTNAARGARTTYGTNTAYCARYTNACNCARATHAAR GTNTTYGARAARAARATHGAYGTNGCNATHACNGCNTAYMGNCCNAAYCARGCNCCNGAY GTNYTNTCNTTYGTNATHCAYYTNAAYMGNAAYGGNAARYTNYTNAARYTNYTNGCNGGN ACNGARGAYCCNATGAARCCNATHTCNGARGGN---------CARAAYAAYTAYATHCAR TAYGARMGNGTNCCNGCNTCNTCNAAYGGNGCNTTYATGCAYAGYYTNTTYCCNTTYACN AAYAAYGTNATHGTNACNAARACNCARGTNGGNAARGARACNGAYCCNAARTAYCAYGGN CCNYTNTGYGTNTTYTAYATHAAYGGNMGNTGGGGNGAYGCNGTNACNGARTGYTGYACN GAYTTYACNGTNAAYGGNTAYCCNYTNTCNAARACN------------------------ ---------------------------------ACNACNGAYACNAARTGGATGCCNTCN AAYCARGAYAAY------------------MGNCCNAGYGTNGCNGARAGYGAYGARGAY GAYYTNGTNTCNAGYATGACNMGNGAYGTNTGYGCNGAYATGYTNGAYACNATHCARAAR YTNAARGCNYTNGGNTCNGAYAAYCCNAAYATGAARAARATHYTNGARATGCARAARCAR YTNAAYGARYTNCARAARTCNYTNACNAARCCN---------AARGGNCCNTCNACN--- ------------------------------------------------------------ AAYAARGTNGAR------------GARAARAARGGNMGNGARTCNAARACNYTNGARGAR ATGGTNGARGARGCNGAYMGNGTNGARMGNCARAARGARGARGARATHAARCARCARMGN GARYTNGAYATGCARACNCARMGNGARGCNAAYYTNAARMGNAARTCNATGTGGGCNMGN AARGTNATHTCNGAYTAYAARCARGARGGN------------GTNAARGGNGAYAARATG AGYGARGARGCNGARAARTTYYTNAARGAYMGNGAYCARMGNATHAAR------------ ---GAYMGNGARGARGTNGARATGGARMGN---MGNAARGCNGARGARATGYTNAARCAR AARGARAAYTGGGAYACNAARCCNGCNACNACNACNAAR------ACNGAYCARMGNCCN AGYCCNMGNAAYGARCCNATHAAYACNACNACNGCNGCNGGNGTNACNACNATGGAYGAR GGNGTNGAYGAYMGNYTNGCNAGYTTYGARYTNGARYTNGCNAAYGARGGNAARATHGAR MGNMGNGTNGAYMGNACNCCNCCNAGYGTNCARCARMGNGAYTAYCAYTCNGAYMGNGAY AAYTTYCARGAYYTNYTNGTN------ATHACNGARGARAARTAYMGNAAYYTNTGGTCN CARAAYCARATHYTNCCNGCNACNTTYCARGTNMGNYTNACNAAYYTNATHAAYMGNYTN TGYCCNGTNCAYAGYTGYCCNGCNAARACNATHTTYAARAGYMGNYTNACNTTYATGGAR CAYTGGTCNATHTTYCAYACNGCNGARACNACNATGMGNTTYTGYCARAARTGYTCNGCN TAYTTYATGACNYTNGARGARYTNGARCAYCAYATH---ATGMGNCAYCAYCARYTNAGY CCNMGNGARGCNGCNGGNYTNGGNGGNAAYGCNMGNATHAARGTNATHGCNAAYCCNAGY TAYMGNGAYCCNTCNCCNTTY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MGN AARGTNAARYTNATHMGNYTNGTNGGNATHATGYTNGTNGTNTTYATHAARGAYGARYTN GTNGCNCAYATHAAYGAYATGGAYGCNGCNTAYGTNGGNACNGGNATHATGGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATHGAYGTNGAYACNYTNACNCCNGAYYTNTCNAARGARATHAAYYTNATHGCN AGYCARTAYGGNATGTCNGAYGAYGAYTTYGTNMGNYTNYTNMGNAARGAYAARGARGAR YTNGARGCNYTNAARGARGCNMGNCARYTNGARGARGCNAARGCNCARTTYTCNGGNMGN AARTCNMGNMGNGARMGNMGNGCNATHAAYGARAARMGNCARAAYCCNCARMGNTTYTGY MGNCCNAGYTAYGCNGCNMGNGAYAGYCCNAARTAYGARCCNTAYAARMGNCCNGGNTCN TCNTCNMGNTCNMGNTCNMGNTCNMGNTCNMGNTCNTCNGARAAR---GARGTNAARTTY ATHACNAGYTTYGGNGGNAAYGARAGYGAYGARGAR------GCNGTNGTNCARGGNCCN AGYYTNCCNGCNACNACNAARGCNAGYAGYYTNAARAARYTNTCN---------GAYTCN TCNAARTGYGARACNCCNTGG------------------NNNTCNAARTCNMGNAARGAY TCNAARGGNTCNTCNTCNTCNMGNMGNMGN---------------------GGNGGNAGY AGYMGNTCNTCNAGYMGNTCNMGNTCNMGNTCNMGNTCNMGNGGNMGNTCNCCNGGNCAY MGNGGNMGNTCNGGNAGYGAYMGNMGNTCNTAYTCNACNTCNAARTCNMGNAGYMGNTCN MGNTCNMGNAGYMGNTCNMGNACNTCNCCNGCNAARACNGTNGARAARYTNCCNGTNAAR MGNTAYMGNMGNGARAGYYTNTCNTCNAAYTCNGAYYTNAGYGGNATGGARTCNGAYGAY GAYGAYAAR---------------TCNTCNYTNTCNAARTCNGGNGAYCARGCNAARTTY AAYTCNGCNGCNGGNGGNAARYTNAGYAGYAARAGYATHTCNCARNNNNNNMGNGARACN CCNCARGARAARYTNAARMGNMGNATGCARGCNCARATHAAYAARCARTTYMGNGCNGAY AARAARGCNGARATHTCNAARATHTCNAARCARGARCARGARMGNYTNGAYMGNGARGAR GARATHMGNACNATGGCNATHGAYATGMGNMGNMGNGARMGNGARAARMGNCAYAARGAR MGNGARGARGARGARAAYGARMGNMGNGAYMGNAARAGYAARAARCAYGAYGAYMGNTCN GGNAGYAGYAGYAGYAGY---AGYAGYAGYTCNGAYGAYAGYTCNMGNAGYMGNAGYCCN MGNCCNMGNAARAGYCCNGAYMGNAARGARGARTCNMGNGARMGNMGNGGNGARGARMGN MGNCCNGAYMGNMGNAGYGGNGGNGGNMGNMGN--------------------------- ------------------------------------------------------------ ------GCNMGNGTNGAYGAYMGNYTNAARGTNTAYAARGCNAARGAYYTNACNGAR--- ------AGYGTNGAYTAYAGYACNYTNMGNGARGCNGGNATGGCNTGYCAYCARYTNMGN ACNYTNATGACNGARYTNTCNAARATHATHTCNYTNGCNMGNATHACNGARYTNCCNCCN GTNAAYGARCAYGGNCAYTTYTAYGAYCCN------------GARGCNGARAARYTNAAR AGYGARYTNTGYGARYTNMGNGCNCARTAYTCNYTNYTNGAYCARACNGTNMGNGAYCAR CARGGNAARYTNTCNYTNTCNMGNCARMGNGARAARGAYTGGGARCAYTCNGTNTGYMGN CAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR GCNATHATGCCNTCNAGYACNCCNAGYMGNTAYGARATHAAYGARTCNGARAAYAAYAAR TAYAARGAYTTYGAYYTNAGYTGYACNAAYTCNTCNTAYATHCARCCNAAYTTYAARTAY GAYGTNAARYTNYTNAARCARAAYCARMGNYTNYTNAARGARGTNGARMGNYTNGTNCAR GAYGTNCAYYTNTCNAAYCARAARAAYGCNCARYTNGTNAARGARATGGARMGNTGYAAR TCNGTNGCNGARYTNGARGAYAARATHGTNGGNYTNATGGCNGARAAYCARTCNCAYGAY AARACNYTNMGNGARGCNGARMGNCAYYTNGAYGARGGNCARMGNMGNAAYGTNGARYTN CARAARMGNYTNAAYCARGCNGAYCARGARYTNGTNGAYTGYAARGARGARYTNGGNGAR YTNMGNATGGTNAARACNGARYTNGARAAYCARMGNGAYGARGCNYTNCAYAAYYTNAAY GARGCNCARGAYTCNYTNGARGARTAYCARAARAARACNAARGAYAARATHAARATGATG GARGARMGNGARGAYGARYTNCARGAYTCNYTNACNTCNACNTCNCARGARMGNGAYGAY YTNYTNGAYCARYTNTCNTCNATGGARATGTCNYTNGCNTCNCARGARGCNCARATHCAY MGNYTNYTNAAYGAYGTNAAYTGYGARGAYGCNMGNGCNMGNGARGTNGARGTNGCNAAY CARCARYTNAARATGCARYTNGARYTNYTNACNGCNCARGCNMGNGAYTGYGARAARAGY GCNCAYGARGCNAARGARTTYAARAAYCARMGNGAYATHYTNMGNACNGARYTNGAYCAY CAYMGNCARATGGCNCARGAYYTNMGNACNATGGTNAARYTNYTNAAYAARAAYTCNAAY GCNATHTAYCCNGAYGAYAGYGGNAAYTTYAGYGTNAARTCNTTYTCNGGNGCNGGNGAR GGNGGNYTNYTN---------------------------GCNGCNGARYTNAAYTGYAAY AAYAAYGGNYTNCCNGGNTGYGARGGNAGYGCNGGNYTNGGNAAYATGGTNTGYGARATG MGNAAYYTNGTNACNAAYATGGAYTGYGARATHCARMGNYTNMGNTCNGAYYTNAARCAR MGNGAYGCNGAYGAYMGNACNTAYTCNAAYYTNMGNGAYGARYTNAARGTNYTNATGGAY MGNGTNGARMGNGGNATGAGYCAYAAYACNGARYTNGGNYTNCARGTNTCNTCNYTNGAR MGNGAYAARAARTCNATHATGTGYAARYTNGARGARACNYTNAAYTGYGTNGARGARMGN GAYMGNGCNYTNCARTGYYTNGARACNMGNYTNAAYGARMGNAGYACNCARATHGTNTGY YTNCARGARGAYATHGAYGARMGNCARGTNMGNGTNACNTGYYTNGARCARCARYTNCAY GAYATGAARAARAARGGNGAYGGNGAYAARAAYAAYYTNGAYTCNCARCCNYTNAARGAR GCNYTNTCNMGNGTNAARGARYTNGARAAYATHYTNCARTGYAARAAYAARTCNGCNGAR GAYYTNCARGAYAARYTNTCNACNACNYTNMGNGARYTNMGNACNACNAARATGGAYATG GAYAARCARGTNGARTGYYTNAAYATHGARYTNTCNGAYAGYMGNCARGARGTNGAYMGN YTNAARGARGAYGGNGARTCNATGMGNCARAARTTYGCNAGYAGYCARAARYTNGTNGAY GAYTCNMGNAARYTNAAYMGNGCNAARGAYGARAARATHGGNTGYYTNAGYGAYGARGTN GAYGARYTNMGNTAYTCNAARGAYAARATGGARCARYTNYTNACNAAYCARYTNAGYGAR TGYGARTGYAARYTNAARACNTGYCARGAYAARAAYAARGARYTNGARAAYGCNYTNYTN ATGTGYCARAARGARGTNTGYGAYCAYYTNAAYAARATGGAYGARATHMGNTCNGCNTTY GARYTNGARYTNGARAAYMGNGAYGCNTGYATHMGNAARYTNAARGAYGAYYTNMGNMGN ACNGTNGARGARYTNAARTGYAARATHGARGAYAAYAAYTCNYTNGARCAYTCNYTNTCN GARYTNMGNAAYAARYTNCARCARYTNTGYTGYCARYTNAAYGAYGCNGARAGYACNATH CARTGYYTNAAYTCNAARGTNGGNGARATGGARAARYTNATGYTNAARGARAARTCNGCN TGGATGAARGARTCNGARGAYYTNGARMGNMGNYTNGCNCARGCNTGYAAYAAYYTNTGY ACNGCNAAYAAYGARATHGAYATHYTNAARCARAAYYTNCARGARAARAARACNCARAAY GAYTGYYTNCAYGCNGARAARACNCAYATHTTYCARGARYTNAARAARACNTGYGAYACN GTNGTNGAYYTNCARGARMGNATHAARAARATGGARGAYGAYAAYCARGARYTNTGYAAR CARYTNCARCARAARATGGARTGYATHMGNGAYYTNGARAAYATGATHMGNATHAARGAY CARGARYTNAARTGYYTNACNAARTTYATHCARGARYTNCARGCNTCNAARGAYAAY--- TCNGAYTCNYTNACNAGYYTNGARGGNCARATHMGNGAYYTNAARGARCARYTNGCNAAR YTNMGNGARGARAARCARTGYAARGCNGCNATGYTNTGYGARTGYGARGARGCNTTYAAR CAYTGYCARYTNYTNAGYCAYGAYAARGAYGAYGARATHCARYTNYTNAARTGYCARATH GARACNYTNAAYAAYAARYTNCARGARMGNGTNGCNMGNGTNGAYGARYTNGARMGNGGN ATHGARAAYYTNCAYAARGAYGTNGARMGNMGNATGGTNMGNGTNGAYGARCARYTNAAR AARTAYGARACNGARYTNATGGAYMGNGTNCARGARATHGCNACNYTNAARGARTGYGTN AARACNTGYGARTTYAAYATGAGYGARAARGTNGARGARATHAAYCARCARGARCARAAR AAYTGYYTNYTNACNGGNGARYTNCARTCNYTNAARYTNCARYTNAARGARACNGARGAY ACNMGNGAYCAYYTNYTNACNCARYTNTCNGARAARAARTCNGARGTNGCNGARYTNTCN CARCARYTNMGNATHAAYMGNGARCARATGCARAARCARCAYGARGAYYTNGTNCARTGY MGNCARTGYYTNTCNTGYGCNCARMGNGAYGCNGAYAARYTNMGNMGNGARYTNGAYGAY GCNATHTCNAAYYTNGARCAYMGNGARTGYGARATHACNMGNYTNAAYGARGARMGNAAR TCNYTNATGGAYAARGGNGCNCARGTNTCNTGYCARYTNGARCAYGARACNGCNGTNYTN CARCARCARATHGCNGARATGAARYTNMGNATGGARAARGARATGGARTGYYTNMGNAAY TAYTCNTGYCARYTNGARACNTCNAAYAAYTCNYTNACNCARAARYTNTCNYTNTCNCAR MGNCARATGATGCARYTNGARAARTGYTAYCAYCARAARYTNGAYAAYYTNACNMGNGAY GTNGARGAYYTNAAYACNAARYTNGTNATHMGNGAYGAYGARATHYTNTCNAAYMGNGAY TGYATHGCNYTNAARGAYTCNGARATGAGYMGNYTNAARMGNMGNYTNTGYAARCAYGAR AARATHTGYAGYGGNTCNAAYAAYAGYAAYTAYAAYAAYAAYAGYAGYGGNAGYGGNAAY AAYAGYGAYGTNAAYGAYTTYATHGAY------------GTNGTNGAYGAYGAYAGYMGN GAYGARGAYAAYGAYYTNGAYCCNGCNAGYGARAAYYTNGCNACNGARAARTCNAAYAAR TCNCARAAYAARGCNGAYAAYACNGTNGGN------GAYMGNGAYAGYYTNGGNGTNACN GARGTNCARGARMGNYTNMGNAAYAAYGARMGNMGNCARAARGCNATHGARMGNCARYTN GARAGYYTN---GARGARATHACNCARAARTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AGYGCNAGYACN GCNYTNGCNGTNGTNYTNTAYCARGARGARAARYTNYTNCCNCAYGARAARAARAAYMGN AGYTTYTCNATHGGNGARCAYAARTTYYTNATHCARCARGAYTGGAAYCARGGNGGNGTN GCNGCNGTNGTNTGGGAYGCNGCNGTNGTNYTNGGNGARTAYYTNGCNTCNCAYMGNCCN YTNGTNTCNGAYAARMGNGTNYTNGARYTNGGNGCNGGNACNGGNYTNGCNGGNATGGTN GCNGCNTCNYTNGGNGCNGAYGTNATHGTNACNGARMGNGARGARTGYYTNCCNTAYYTN GARACNGCNATHGCNGARAAYGARCARGGNAARAAYTGGMGNATHAARGCNGARGTNYTN GAYTGG------ACNCARCAYYTNGAYGTNACNACNTGGGGNCAYTTYGAYYTNGTNATH GGNGCNGAYATHGTNTAYATHGARAGYACNTTYCCNCAYYTNYTNAARACNYTNCARTCN GTNACNACNTCNTCNMGNACNCARGTNYTNYTNTCNTGYMGNATHMGNTAYGAYMGNGAY YTNAARTTYYTNCAYATGYTNAARAARATHTTYTGYGTNACNGARATHTTYTAYGAYTCN AARYTNGAYATHAARATHTTYTCN---------------YTNGTNACNCAYTAYGGNGGN TGYCAYTGYGGNGCNGTNMGNTAYTCNGTNCARGCNTCNACNCAYYTNGAYATHGTNCAR TGYAAYTGYACNATHTGYYTNAARAARCARAAYCAYCAYTTYATHGTNCCNAARTCNMGN TTYAARYTNACNAARGGNAARAAYTCNYTNACNACNTAYACNTTYAAYACNCAYGTNGCN AARCAYACNTTYTGYAARGTNTGYGGNGTNCARAGYTTYTAYAGYCCNMGNTCNAAYCCN GAYGGNTAYGGNATHATGCCNCAYTGYYTNGAYCCNGGNACNGTNGARTCNACNGAYGTN ATHATHTTYGGNGGNGAYGARTGGGARAARTCNTTYCARAARTCNAAYATHACNGARTAY TCNAARAGYTCNGCNCAYYTNGTNTTYAGYTAYGGNACNYTNAARMGNTCNGARMGNAAY TAYGAYGTNATGACNATHAARGARMGNGGNATGTCNTCNTTYGTNGGNAGYGGNGARACN ATGTCNAARTAYCCNYTNGTNGTNGGNACNAARTTYGAYATHCCNTTYYTNATHAAYYTN GARAAYCARGGNCAYAAYATHGTNGGNGARATHTTYGARGTNGAYGAYAARATGYTNGAR TTYYTNGAYGARTTYGARGGNCAYCCNCAYTTYTAYMGNMGNCARGARATHTTYATHYTN ATGTCNTCNGAYAARGARGAYAARGTNYTNGAYTCNCCNAARACNCAYAARTGYTGGGCN TAYTTYYTNAAYAARATHGARGARGGNGTNYTNGARAARGARTGGYTNAARGARTTYMGN GGNCCNTCNGARAAYAAYAGYAAYGCNACNATHGTNGARMGNYTNAARGAYGCNGCNAGY TTYGARGAYACNMGNTGYAARTGYGTNTGYTCNCARACNCARGAYGCNCAYGGNAARCAR ACNAARTCNGTNTTYMGNAAYACNATGMGNAGYGARCARTGYGAYTGYGARCAYGTNGTN AARCCNGTNGCNCCNACNCARTTYTGYTCNYTNTGYAARTGYCARACNGARACNMGNAAY ACNACNACNATHAARGTNGTNGTNATHTTYATHATHTGYGTNGTNTCNYTNYTNTTYGTN TAYATGYTNTTYYTNYTNTGYYTNGAYCCNYTNYTNCARMGNMGNCCNAAR---TCNTAY CARCARCAYACNAAYGARGARGTNAAYYTNGARGAYATGTCNTCNTCNMGNGCNGGNTCN GGNGARGGNCCNGCNACNCCNACNTCNTCNACNACNAAYACNACNGCNATGTCNGCNMGN CARMGNTCNYTNYTNAAYATHGTNACNAARGARCARAARAARTGGAARGGNACNGTNCAR GARCARMGNMGNAAYATHTAYGAYMGNCAYTCNATGYTNAAY------------------ ------------CCNYTNYTNACNTTYGGNATHATHGCNGAYGTNCARTAYGCNGAYTCN GAYGARGGNACNGAYTTYTCNAARYTNMGNGTNMGNTAYTAYMGNAAYTCNYTNAAYYTN YTNAARAAYGCNGTNAAYGAYTGGAARMGNTGYCCNGAYAARGTNACNTTYGTNYTNCAR YTNGGNGAYYTNATHGAYGGNAARTGYGCNGGNGGNYTNGCNMGNAGYCAYAARTCNYTN AAYACNGCNYTNGAYCCNTTYAAYTCNYTNMGNGTNCCNGTNTAYCAYYTNTTYGGNAAY CAYGARTTYTAYAAYTTYGAYMGNTCNTTYTAYYTNAARTCNCCNYTNAAYTGYGCNYTN ACNAAYGAYATH------------------CARTGYGARGCNGAYMGNYTNTAYCAYACN TTYYTNCCNCAYCCNAARYTNMGNATHGTNACNYTNGAYACNTAYGARYTNGGNGTNYTN GGNTAYTCNGAYGAYGTNGARAAYGARAAYTAYYTNAARGCNAARTCNYTNYTNGARGAR AAYAAYCCNAAYGCNGARAARAAYGAYACNAGYGGNYTNGTNGGNTCNGCNAARMGNTGG GCNGCNTTYAAYGGNGGNYTNGGNGARAARCARYTNAARTGGYTNGCNCARGTNYTNGAR MGNGCNCARYTNAARGARGARAAYGTNATHATHGCNTCNCAYATHGGNTTYCAYTCNTCN YTNCCNGARAAYTAYTCNGTNTGYYTNTCNTGGAAYTTYCARGARGTNATGGAYATHGTN CAYCAYTAYMGNTGYGTNGTNGCNATHTTYGCNGGNCAYGARCAYGCNGGNCAYCARCAY YTNGAYGARCAYGGNGTNCARCAYATHGCNTTYCARGGNGTNATHGARACNAARCCNGGN AGYGAYGCNTAYGCNACNGCNMGNYTNTAYGAYAAYGARYTNATHGTNACNGGNGTNGGN MGNGTNCCNGAYTTYAAYATHGCNYTNAARTTYCCN------------GTNAARMGNAAY TGGACNYTNMGNTTYACNCARGARGGNATHTTYGARCCNAGYGARTCNGCNGARTAYATH ATHGCNCAYGCNYTNGGNGARAARTCNYTNGTNAAYGTNAAY---CAYGCNMGNTGYYTN ACNAARGARCARACNGARACNATHMGNMGNYTNTGYAARGARMGNYTNACNGGNAARCCN ATHCARTAYGTNATHGGNGARTGGGARTTYCAYGGNATHACNGTNGAYYTNAARCCNCCN GTNYTNATHCCNMGNCCNGARACNGARCARYTNGTNGAYYTNGCNATHACNGAYATHCAR GAYCAY---------------MGNTCNGARYTNTTYAARTGYATGGARATHGGNTGYGGN TCNGGNGCNATHTCNYTNGCNTTYYTNCARGCNTTYCCNCARGTNCAYGTNACNGCNATH GAYYTNTCNCCNACNGCNTGYGAYYTNACNAARCAYAAYGCNGCNAARTGYGGNGTNATH GARCARATGGAYGTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GGNACNCCNGARGTNGGNGCNGTNAAYTTYAAYGTNYTNCAYACN YTNYTNCAYGCNGTNYTNTCNAARYTNGAYYTNAARGAYGTNAARGCNGARYTNAGYGAR ACNGAYCARCARYTNYTNTCNGTNCCNGARGGNGTNMGNGTNCAYTCNGCNACNAGYGCN GGNAARGAYAGYYTNGARACNGAYGGNGARAGYGTNAARGAYGTNGARCCNGTNCCNAAR AARTCNCAYTAYCAYGCNYTNGARGCNAARGTNTCNAARYTNGARAARGAYYTNGARAAY YTNAAYAARYTNCCNAGYAAYGARGAYYTNTTYGAYMGNGCNAARCCNTCNAARCCN--- AARCCNGTNACNGAYATGTGGCARTCNATGCARYTNGCNAARMGNGTNGAYGCNAAYGAR GCNGGNGTNGGNAARYTNATGTCNATGGTNGARGAYYTNYTNAARGARATHCARGARYTN AARGCNGTNAAYGAYGCNYTNMGNAAYCARYTNGARGARGCNAAYATGAAYGARYTNMGN AARMGNYTNAARGAYYTNGARGAYATGTTYGARAARATHAARAAYGARATGAARGARATG AAYAAYAARGTNGAYAAYATHCCNGARATHCCNAARATHGARCARTAYACNGGNCCNTTY GTNACNTGGGARGCNYTNGARAARATGYTNAARGGNATGMGNGARGAYYTNMGNCCNAAR ACNCCNCCNCAR------------GCNATHGARGCNGCNATHCARACNGARACN------ ------CAYYTNCCNMGNCCNGTN---------------------TCNTCNTCNCCNTCN AARGARYTNCARGAYATHYTNGARAARYTNGGNAARYTNGGNGTNMGNCAYGAYGARYTN GARGTNMGNGTNACNATHATHGARGARGARYTNGGNAAYAARGCNAAYAARTCNGAYYTN GARGGNYTNGGNGTNCCNGAYGAYYTNYTNGCNCARYTNGARAARATHAARGARGAYYTN GAYACNYTNATGMGNYTNMGNGARMGNGAYACNGAYGCNYTNAAYMGN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGTTYAARAAR CCNAARCARAARGTNGTNCARAAYGGNAGYMGNGARTCNGTNGAYAGYCARYTNTCNACN TCN------AGYAAYGARAAYYTNTCNCCNAAYACNAARGARAAYAARGAYACNGTNGAY AARATHYTNCAYCARMGNGTNCAYTTYCARGTNTAYTAYYTNGGNYTNGTNCCNGARATH AAYYTNACNAAYTCNAARAARMGNGAYACNGARGCNCARYTNATHGAYATHGTNGARGAR AGYCARATHGAYGGNACNYTNCARGTNACNGCNACNGARGARAAYAARGTNGTNATGAAY GTNTCNMGNCAYGGNATHAARGTNYTNGAYATHGCNGGNAARGARGTNYTNCARMGNCAY CCNYTNCAYACNATHGCNCARYTNACNGARTAYAGYGAYGGNTTYGGNMGNCARAAYATH GCNGTNAARATHGGNCARGTNGGNAARAAYGTNAAYCARTGYTAYGTNTTYCARTGYCAY TCNGAYTGYTCNACN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GGNTGYGTNYTNTGYGTNYTN GGNTCNACNGTNATGGTNATHCAYTCNCCNAARGARCARGARATHCAYGAYGTNGARGAY YTNYTNATHAARATGAARGARCCNGGNTTYATHYTNTAYACNYTNTGYYTNYTNTCNGTN TCNYTNGCNATGATHTTYTAYTTYGCNCCNMGNTAYGGNCARAARAAYGTNYTNGTNTAY ATHACNATHTGYGCNTCNYTNGGNGCNTTYACNGTNATGGGNTGYAARGGNGTNGGNACN GCNATHACNGCNACNGCNMGNGGNCAYAAYGARTTYAARAAYTGGYTNACNTAYGCNYTN ATHGCNGTNGTNGTNGTNTGYATHYTNYTNCARYTNAAYTAYYTNAAYAARGCNYTNGAY ACNTTYAAYACNGCNGTNGTNACNCCNATHTAYTAYGTNTTYTTYACNTCNTTYGTNATH GTNGGNTCNGCNATHYTNTTYAARGARTTYTTYAARATGAARYTNYTNAAYATHGTNGGN GAYYTNTGYGGNTTYTTYGTNATHATHATHGGNATHTTYYTNYTNAAYGCNTTYAARGAY YTNMGNATHTCNYTNMGNAAYYTNCCNAARGCNTCNAARGARGCNGAYGCNATGGGNTTY AGYGAYGTNATHTCNGARAGYTGYAGYCAYATHGARGCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TCNGGNACNMGNYTNGAYGAYTCN AAYGARGAYAARGTNACNYTNYTNMGNMGNGARAARCARATHTCNTAYGGNMGNAAYACN GAYTCNTAYAARCARTAYATHGARACNGTNCCNAARGGNGARMGNTGYGARGAYMGNAAR AARCAYCCNMGNACNCCNGTNAARTGGTTYAARTGYAGYMGNMGNAAYTGGGAYGCNCAR GTNGCNGCNTGGAARMGNCAYATHCAYGARTGGGCN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNTCNTAYMGNAGYTAYTCN---GAYTCNMGNTAYAGY GAYTCNAGYMGNTCNMGNAGYMGNTCNTCNMGNAGYTAYAGYMGNAGYMGNTCNMGNCAY MGNTAYMGNMGNMGNTCNTCNTCNAGYMGNGAYMGNACNMGNAGYTAYAGYTAYAGYAGY MGNAGYAGYTCNAGYMGNTTYCAYTCNMGNTCNTAYTCNMGNTCNMGNAGYTAYACNMGN TCNMGNTCNMGNACNMGN---AARTAYCAYAGYACNTCNMGNAGYCCN---TCNMGNMGN ACNGCNAAYYTNAARMGNATHYTNAARTCNCCNYTNGGNATHGTNCCNGTNACNAAYATH ACNGTNGCNCCNGTNACNAAYGAYACN--------------------------------- ------GGNGGNGGNAGYGCNATHAGYACNAAYCCNCCNGAYGAYATHCCNYTNCCNGGN AARGARGCNCCNACNTCNTCNACNGCNACNACNGCNGTNACNAGYCCNAARGARAARGCN GTNYTNACNGAYATHCCNYTNCCNTCNACN---------ACNACNGCNGCNGGNAARCCN GTNTCNGAYGGNAARGARAAYAAYAAYACNCCNGCNGTNGARTCNGGNACNGGNGAYGCN ------------------------------------GGNGCNAAYCCNGGNGGNTCNTCN TCNGTNGAYGTNGCNGCNAAYGARCARGGNAAYGARACNGARAAYCCNGCNGGNGAYGGN GCNGTNGAYGARAGYCAYCCNGARGARACNGGNATGYTNAAYGCNAAYACNAAYATGATG GGNTAYGAYCARGARGCNTAYAAYCAYGGNGGNTAYGGNAAYGTNGAYTCNGCNTTYTGY GARGAYACNGGNTAYGAYAGYTTYGARTTYGAYGGNGCNGGNAAYTAYGAYCAR------ ---CARGGNTAYGAYGAYCARGAR---TAYGAYTAYAAYYTNGAYCCNTAYCAYCAYCCN CCNYTNMGNCAYCARGGNCCNCCNCCNATG---------MGNGGNCAYCCNCCNCCNGGN TAYMGNGGNCCNCAYCCNMGNATGTTYCCNCCNGAYCCNMGNTTYGGNCCNCCNMGNCCN GGNATGGGN---CCN------------------CCNMGNATGMGNYTNAAYGGNCCNATG GGNCCNMGNGGNYTNMGNCCNCCNATGGGNCCNGGNGGNCCNATGGGNCCNCAYGGNATG MGNGGN---CCNCCNMGNGGN---CCNCCNMGNGGNCCNCCNGGNATGMGNGGNCCNCCN GGNATGCCNGGNYTNMGNGGN---CCNCCNMGNCCN------ATGGGNCCNCCN------ GGNCCNATGGGNCCNAAYGGNCCNMGNCCNMGNATGGGNCCNCCNCCNAAYMGNATGGGN CCNYTNATGCARGGNCARGGN------------GGNCCN------------AAYMGNAAY MGNATGGGNGGNCCNCCNCCNATGTCNGGNCCNCAYCCNMGNGARGGN---TTYCCNYTN CARMGNCCNGGNATGCCNCCNCAYYTNMGNGGNCCNATGCCNTCNCARATGMGNGGNGCN GTN---CCNAAYYTNGGNCARCCNCCNCCNAAYTTYAAYATGCCNCCNCCNTCNGGNCCN GTNGCNAGY---TCNAAYGCNGAYGGNTCNGTNAARCCNACNGAYTCNYTNGARCCNCCN CCNYTNCCNCCNCCNAARCCNCCNACNCCNCARCCNCCNCCNCCNCCNAARAARGARGAR GARAARAARGARGARATHAARCCNATGGTNCCNGAYATHCCNCCNGARCARGCNGARCAR TAYMGNAARYTNMGNGARCARGCNCARAARCAYGCNAARAARCARCARMGNAAR------ ------GCNAARGGNGARCCNGARAGYAGY------GAYGARGAYGARGARGCNGTNMGN MGNATGGARGAYGCNGTNAARYTNGCNGCNGARCARMGNGARATGGARGARGCNGCNYTN YTNGCNGCNCARGGNGCNGAYAARGTNGCNGTNGARGARGGNGGNGCNATHYTNGTN--- TCNTCNCCNAGYCCNYTN---GTNCARCARCARGCNGTNTAYATHCARCARCAR------ ------ACNATGGCNAAYGCNCAYGCNGCNTAYGGNYTNACNTCNACNCCNCAYATGGTN CAYACNGCNCAYCCNGCNYTNCARGCN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------AARACNGTNTTYGGNACNCCNTGG ACNTTYAGYGGNATHATGTCNMGNGAYGGNGGNGTNYTNCARTCNGARAAYTCNGAYGTN GCNYTNGTNGTNGARMGNAAYGCNGTNYTNGARGGNGARATGGTNTCNATHCARGGNGCN ATHTTYACNGAYGTNGTNAARATHAARGARAARTTYGAYYTNCCNCCNAAYGARATGYTN ATHACNCCNYTNGTNGARTAYCAYGCNCARGGNGCNTAYCARTTYCARCAYCAYGTNTCN GTNAARYTNCCNCAYGCNYTNCCNGARGAYTTYGAYGTNTCNGAYATHAARTTYTAYACN TTYAGYGTNGAYGGNGARGGNAAYACNGTNATHCARACNYTNTCNCARAARTGYAARGAR AAY---ATHAAYGTNGAYGCNTAYTGGGARTCNGGNCARGARCARTAYYTNATHGCNAAR ACNACNCAYTTYAGYGGNTAYTTYTGYACNATHTGYGARACN---AARAARYTNCCNTCN ATHTGYGCNMGNGTNTTYGGNTCNCAYGTNCARATHAARTCNAAYMGNMGNGARATHMGN YTNATHYTNTAYYTNTGGGAYMGNMGNYTNAAYATHAARGAYTTYATHCARGAYATHATG CARCARGARTTYGAYATGGAYMGNCARYTNYTNACNGAYCARACNGTNCCNYTNYTNATH GAYGCNACNTCNGAYGTNMGNMGNYTNATHGARTGGGCNATGGARAAYGTNCCNGGNACN YTNCCNAGYTCNGTNTTYCARTGYYTNATHGARATGGTNCAYGTNCARGARGAYGTNACN YTNTTYGARGAYGCNTTYGARAAYGCNAAYGAYGARTAYCARMGNACNTTYTAYATHMGN AAYYTNAARYTNGARGCNATHGARGARAGYATGTTYCCNTCNATGGARATHGTNAARAAR ACNATHTCNCARGTNATHAGYCARCARGARATGGARACNATHTGYCARGCNTAYGGNATH AGYAARAAYATHATHGGNAAYYTNAAYATGAARTCNAAYACNGGNGAYTCNATHAARAGY ATHYTNYTNGARGARTGYTGGAAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------MGNYTNMGNGARGARCARCARAARGCNATHTCNGARACNGAYGAR MGNATHAARCARTTYGARAARTAYAARTCNGAYTAYAARTCNYTNCARAGYMGNYTNAAR ACNYTNCCNGAYAARYTNTCNCAYGAYGTNATGGTNCCNTTYGGNAARYTNGCNTTYATG CCNGGNCARATHGTNCAYACNAAYGARGTNYTNGTNYTNYTNGGNGAYAAYTGGTTYGCN GARMGNTCNGCNAARCARGCNTGYGAYATHGCNAGYMGNMGNGTNAARGARYTNGAYACN MGNATHAARGARYTNAARGARCARAARGGNYTNYTNGARCCNMGNYTNGGNATHACNTCN GARYTNCARGCNGARATGGARGGNMGNGGNGAYTAYGARGARATHATHGARGARTAYGAY GARGARAARGARAARYTNTGGGAYGARCARCAYAARGTNAAYYTNMGNMGNTAYCARGAR GARTCNMGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNGARATHCCNGARGARGAR GARACNCCNAARAARAARYTNGTNYTNGTNACNATHGGNTAYTTYATHYTNAGYCARAGY TAYGTNGCNACNYTNATHGTNATGATGGCNTGGAGYATHACNTAYCAYTGYTGGYTNACN TTYGTNTAYYTNYTNGCNGCNTGYATHATHTGGATGATHCCNAARCCNAAYMGNGTNGTN YTNAAYYTNTCNCCNYTNATHYTNGCNTAYGCNGARGTNYTNGCNATHGTNYTNYTNCCN GCNATHYTNYTNYTNGGNTTYYTNATGGTNGTNGGNTGYGTNGGNAAYTCNYTNGTNTTY TAYGTNTAYYTNACNAARTTYAAYCCNAGYTCNACNMGNACNGCNATHYTNGCNYTNGCN TCNTTYGAYYTNGTNGCNAGYTGYATHTCNATGCCNGGNGARATHATHGAYATHMGNTAY TCNTAYAAYTTYCARAGYGGNGTNGTNTGYAARTGYTTYMGNYTNTGYACNATGYTNGTN YTNATHGCNTCNGGNYTNACNYTNGTNGTNGTNGCNGTNGAYMGNTAYMGNMGNATHTGY MGNCCNYTNAAYCAYCARATGACNGCNGGNCARACNAARATHTGGGTNGCNGCNTCNYTN GTNGGNGCNATGGTNTTYTCNATHCCNTCNCCNATHATHTAYGGNYTNTCNMGNGTNGAR GGNATHTAYGGNGTNGARTGYTCNATHGARCAYAARTAYCARAARCAYCCNYTNCCNTTY GTNTAYAAYYTNATGTTYGCNGTNYTNTTYYTNGCNGTNTTYTCNGGNYTNACNATHYTN TAYATHYTNYTNGGNMGNCARGTNYTNAARCARACNCARTTYCARGARGAYCAYTCNATH ACNGAYGGNACNMGNGAYATHTCNAARCARACNGARGGNGTNCCNGCNTCNCCNGTNCAR CARMGNCARMGNAGYTCNCCNCCNCCNMGNAARATGTCNACNATGYTNAGY---YTNMGN CARTCNTCNYTNGGNGAYMGNMGNACNMGNAARACNACNATGATGYTNTTYATHYTNACN GCNACNTTYGTNATHAGYTTYYTNCCNCAYYTNATHYTNAARGGNATHCARGCNGTNAAY AARGAYTTYYTNGAYAAYGCNTCNGAYGCNGAYATHGTNYTNTAYAAYATHTTYGTNMGN TCNTAYTTYTTYAAYAGYGTNGCNAAYTGYTTYATHTAYGGNTTYTGYAGYCCNAARTTY MGNMGNGARTGYAARTCNYTNGGNGAYATHGTNATHGGNTAYCAYGAYGAYGAYYTNGAR TTYGTNAARAARYTNGTNGTNAARYTNMGNATGAARGAYYTNAGYGTNTGGTAYAARCAR CCNGGNGAYGAYGGNAARAARACNAGYGARGCNATHYTNGGNTGYAARGTNTAYYTNCCN ATHYTNACNGARYTNGCNGCNGTNGAYAARMGNATHCARGARCARYTNTCNYTNGCNTAY ATHTCNAAYTCNGCNATHTAYCCNYTNAGYMGNGTNTAYTTYGGNAGYYTNGCNCCNAAR YTNAAYGGNGGNACNMGNYTNATGYTNGCNAARATHAAYTGGTCNTTYGTNGTNAARGAY AARGAYTTYGARGARMGNACNGAYGCNGTNATHGCNTGYATHCARAARGAYATGGARAAY ATH------ATGGCNGARCCNTGYYTNGAYGARTCNGGNGARGTNGTNAGYCAYGGN--- ---ATGMGNTTYCCNTCNAAYATGAAYCAYATHCCNAGYTCNGAYGGNCCNGARTTYGCN TCNTTYAAYCARGGNATGGAYYTNACNTCNATHAGYAARGAYACNCCNTTYTGGGAYMGN CAYTTYAARGGNAARAGYGARGTNACNTGGATHGARTTYMGNAAYAARTTYYTNGCNGAY TAYGGNCCNAARATGGTNGARGGNTTYTCNGAYTCNGARGARGARMGNAARAAYYTNTTY GTNAAYYTNATGTAYAARGAYGTNTTYAAYYTNAGYAARGTNGTNAARMGNTCNGTNTAY GAYAARTTYTGYGGNAARCCNCAYCCNCAYGCNTTYTTYACNMGNATGCARGAYTAYGTN ATGGCNTAYGCNTCNYTNMGNGARGTNYTNGGNATGGARAGYAGYYTNMGNATHCCNACN ATHCARAAYYTNGGNAGYTTYCARTTYCCNGCNATHGTNGCNGCNYTNTCNGAYATGYTN AARGAYGAYGAYCCNAAYATHMGNGCNGTNACNGCNATHGCNYTNGCNCAYGCNGGNAAR AARAARGARTCNACNATHGAYAARATHATHGGNYTNYTNGARGAYGARGAYMGNYTNGTN MGNGARAGYGCNTGYYTNAGYYTNGGNTAYYTNMGNTCNACNMGNGCNGTNAGYCAYGTN GTNGAYMGNTGGMGNAAYGAYCCNATHTCN---------------ACN---GTNMGNGTN ACNCARGTNYTNTCNTCNGAR---------------------ATGAAYGCNYTNAARCCN ------------------------------------------------------------ ------------AAYAGYTCNTTYGGNTAYGCNGTNGCNCARCAYATHGAYCARTCNACN AAYTGGYTNYTNATHGGNGCNCCNMGNGCNCARACNAGYCARCCNGGNGTNACNMGNGGN GGNGCNGTNTAYMGNTGYAARACNAAYAGYATHAAYTCNTGYCARGARGTNCCNTTYGAY AAYGCNGGNAAYAAYATHAARTTYGAYAARGAYYTNMGNGAYTTYATGCCNATGGARGAR AARTCNAAYCARTGGTTYGGNGCNACNATHAARAGYTCNGGNGAR--------------- ------------------------------------------------------------ ------------------------------------------------------ATHGAR GAYATHGARMGNAARATHCARAAYTGYGARAAYMGNYTNGAYGARATHGARMGNAARGAY MGNYTNGTNGARATGACNGAYGARGARTGYCARGAYYTNAARAAYGARAARMGNGCNYTN GAYAARCARGTNYTNAAYTAYAARACNGARATGMGNGGNYTNMGNTGGCARAAYTGGAAR ACNACNGTNACNTCNGTNATHYTNTTYGGNGTNATGTAYGCNGTNTAYGCN---GTNTAY AAYTCN------GTNTCNGTNTCNGGNATGAARATGGAYATH---GTNCCNAGYCCNAAY YTNATGAAYACNCCNTTYACNGCNAGYYTNCAYTCNTTYTCNATHTAYGAYCAYGARAAR CCNAAYACNTGGGGNGAYTCNAARTTYMGNAAYGTNGAYATGAGYGGN------------ ------YTNACNGARGARGGNGGNYTNYTNGAYGAYAAYYTNGARGAYAGYTCNYTNAAR AGYATHYTNACNCCNGARYTNYTNAGYTCNATGGCNTCNTCNTCNTCNGGNYTNGCNCCN ACNTAYCARTGGCARAAYAARTAYAAYCCNGARGARTCNCARGGNCCNTCNACNGARTCN ---------------CCNTTYATHCARYTNGGNATGGAYTCNGAYYTN---YTNATHTCN GAYYTNYTNAAYATHGAYTCNGAYGAYAGYAARTTYTCNGCNTTYGAYTTYGARTTYAAR TCNATGCCNTCN---------TCNTCNTGYCAYACNCCNGTNCCNYTNGAYTCNAARCCN GAYMGNGGNGARATGTAYACNGCNMGNGAYAGYTTYGTNCCNATHAAYAARGARGTNCCN TCNAARGAYAGYATHGARGCNGAR------------------------------TTYTGY CARAARAARTTYCCNATHAARCCNAAYTTYCCNCCNMGNAARTCNCARCCNCCNATHGGN GTNGTNTCNCCNGTNAARATHYTNGARGAR---------------------ACNAARMGN TTYGARYTNYTNACNAAYACNAARAGYGGNTAYGARGAYYTNAARGTNCCNGTNTCNAAY ACN------------TGYTTYTCNTCNGTN---------------GAYATGACN------ ---------GARYTNCCNCCNCARACNGTNCCNTCNTTYGGNGTNTCNGCNGAR------ ------GARACNATHAARATGGARCCNACNTCNCCNGAR---ATGGCN------------ ------------------------------------------------------------ ------------------------------------------------------AGYAAR AAR---GGNCCNYTNAARMGNCCNTCNTAYGAYTTYTGGGAYGAYGAYTCNGAYAGYGAY TAYCCNTCNGAYACNGAYGAYGAYTTYGCNGAYATGAARCCNGGNGARTGYGARTCNYTN ATHGCNATHGGNAARAARCARAARCARTTYTTYTGGCARTAYAAYGTNCARTCNAARGGN CCNAARGGNACNMGNYTNAARYTNGCNGTNGARACNCCNGCNGAYCCNCAYGTNYTNAAY GGNTTYGARGAYCCNGTNTTYGAYGARGGNAAYACNATHATGGCNGGNATHMGNCAYGGN GGNAARGCNMGNAARGGNGAYGGNAAYGARGTNTCNCCNAAYCCNAARAARNNNTTYAAR ATHGGNCAYCARYTNYTNMGNYTNAAYAARAARATHAAYTCNTTYCARYTNGGNTCNGAY GTNCCNYTNGCNAARAARAAYGARTCNCAYAARGARAARAAYAARYTNTCNTCNMGNGCN TGYMGNYTNAARAARAARGCNCARCAYGARGCNAAYAARATHAARYTNCAYGGNYTNGAR AAYGARCAYGGNCARATHAAYAAYGTNYTNMGNYTNATHTGGCCNGARYTNMGNGARMGN GCNAARTGYYTNMGNAAYCARCARGTNTCNGAYGARAARCAYTCNTTY---------GAR GAYAGYYTNACNAGYAARYTNACNGAYTAYATHTCNTCNAAYYTNAARAGYATGGTNGCN GGNAAYACNACNGARTAYGTNAAYAAYGTNATHYTNGGNGTNGARAGYGGNGAYTGGAGY GGNGGNYTNAAYATH---AARCCNMGNAARACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ACNCCNAARTCNGCNYTNCAYACNMGNMGNTCNATGATHCAYTCN---TCN AGYTTYAARGARCCNGGNATGCCNYTNTCNGCNYTN------MGNAGYGCNGGNMGNMGN AARACNGARTAYACNCCN---TCNAARACNCCNYTNCARMGNATHAAYATHYTNAARAAR AGYCCNATGATHGARATGGGNMGNMGNMGNTCNMGNCAYGTNTCNTCNCCNGCNYTN--- AAYAARGGNCARTAYTTYMGNGAYYTNGTNTCNAAYGARACNGAYCAYYTNAAYTCNYTN TGYAGYAARTGGAAYGAYTAYACNGARCARGARCAYGGNYTNMGNGARGARGAYYTNGGN CAYATHMGNTGYGCNGTNGGNAARGCNYTNYTNYTNATHGGNCARMGNTTYAARCARTTY ACNGGNYTNGTNGAYAAYTAYGTNTAYGAYACNGGNGARAARAARACNACNCCNTCNGAY YTNCARGGNTTYTGGGAYATGATHTAYTTYCARGTNGARGAYGTNAAYTCNYTNTTYAAR GAYYTNGAYGARAARAARCARTCNAAYTGGCARGTNAAYGARGTNGTNACN--------- ---------AARGTNGARACNYTNYTNAARAARAARCCNAARGGNAARCCNATHACNAAR AARGTNAARTCNAAYTTYGCNGCNTTYMGNGCNGARATGATGAARAARAARGCNACNGAR GCNACN---------ATHGARGAYYTNAARAARATGAARGTNCCNGARYTNAARCARGCN YTNAARGAYAARGGNYTNTCNACNACNGGNACNAARCCNGARYTNATHAARMGNYTNGTN GARTCN---GGNMGNTCNYTNGAYAGYTCN---GAYGCNGTNYTNGAYGAY--------- ------GAYGARATHYTNYTNAARGAY--------------------------------- ---GAYCCNGCNACNGCNACNCCNACNCCNAARTCNGTNCCNGARAARCCNGAYAAYGCN ACNAAY------------GGNAAYGGNGTNTCN---AARAGYGAYGARCCNGARCCN--- ------ATGCCNGCNGAYACNACNGCNGCNGCNAARCCNACNGARGTNTCNAARYTNACN GARGCNGARMGNYTNAARATGMGNGCNGAYAARTTYGGNGCNAAYTCNGARAARGCNAAR AARGAYYTNMGNGCNCARMGNTTYGGNATHCCNTCNTCNGARAAYCARTCNGGNAARATH AGYTCNTCNAAYGTNCCNGTNGAYYTNGAYAARYTNAARAARMGNTCNGARMGNTTYGGN GTN------------TCNACNAGYTCNGCNACNGARGAYGARAARAARMGNAARMGNGCN GARMGNTTYGGNATHACNTCNACNACNACNACNACNTCNTCNAAYATHACNYTNAAYTCN ACNGAYGGNGARYTNGAYGCNAARAARMGNAARMGNGCNGARMGNTTYGGNYTNAARACN ------------------------------------------------------------ ---------------------------AARAARTAYGCNTGYYTNTGGMGNACNTGYAAR GTNTAYGAYCARCCNGCNYTNTCNGGNTCNTGGYTNGARMGNCAYATHGTNTCNCAYGGN GGNCAYMGNCCNTTYAARTGYATHGTNCCNAARTGYGGNCARMGNTTYCCNTCNCARATG GCNYTNGARAARCAYGTNAAYGGNCAYTTYGCNAGYTCNAGYCARGGNGCNACNAARAAY GGNMGNACNMGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GGNCAYCAYACNGAYMGNCAYGTNGAYATGGCNGCNYTNTGYCAYTGYTAY GGNTCNAARGCNGGNMGNAAYYTNGTNYTNCCNGGNTGYYTNGCNCCNACNAARGTNAAR GAYTCNCCNGGNCAYYTNACNTCNTGYATHATGAARAARCAYAARGARGCNYTNATGGAY ATHAAYMGNAARYTNGTNGARACNGCNTCNTCNGARAARYTNCCNYTNGAYYTNTCNMGN ATHTCNGGNMGNGTNACNGCNGAYYTNYTNGAYTCNACNYTNGCNYTNTTYAARGGNAAR TAYCAYYTNATHMGNMGNCAYYTNGARACNYTNCARATHACNATGGCNACNAGYCARACN YTNAARCAYCCNTCNTCNYTNCAYTAYGAYACNGTNGTNGCNAARGARAARACNYTNYTN CARGCNATGGCNGAYTGGGARGGNAAYAAYGAYGAYGAR---------------GARGAR GAYMGNTCNCCNTCNGTNTTYGCNATGYTNTCNAARATGYTNYTNTCNGARATGGARAAR GARGCNGAYGARMGNGARATHACNYTNGAYGAYTTYYTNCAYYTNYTNGTNTAYGCNTAY TCNYTNTCNGAYGARACNATHGARAAYCARGAYGARATHCARYTNYTNCARGAYMGNYTN GTNCARGCNATHATHAARGARAARGGNTAYYTNAAYCCNYTNGTNCARGCNGTNGTNGGN GARAARGTNACNGAYGCNATHYTNCCNGAYYTNGTNGARAGYGTNTGGGAYAARATGTCN GCNYTNACNGARGCNMGNMGNGAYYTNAARGARTTYGGNGAYYTNATGGAYCCNGGNGGN GCNATGAGYCCNGCNAGYYTNAARCCNYTNYTNMGNCARGTNATGGARMGNATHGTNGAY CCNAGYAARCCNGARYTNCCNGAYYTNGARTGYAARTCNGGNGGNYTNAARGAYYTNYTN AARTCNGGNTTYGGNTTYTTYAARAGYTCNGCNAARCCNMGNCCNGGNGAYGCNCCNYTN YTNATGGTNYTNGTNGTNGGNGGNGTNACNGCNTCNGARGTNMGNCARGTNAARGAYATH GTNAGYAGYGCNAARCCNGGNTTYGARGTNGTNGTNGGNGGNACNMGNATHAGYAAYGTN GARTCNACNYTNGARAGYYTNYTNGTNAARGAYAGYATHAAYGTNAAYATGYTNAARGCN TCNYTNAARAAYAAYGARTGGGTNAARATGGAYACNTGGGARAGYGARCARAGYTCNTGG TCNGARACNATHAARGTNYTNMGNCAYATHAARCARYTNATGGARACNCARTAY------ GGNACNAARCCNTCNCCNAAYAARMGNMGNMGNAARCARCARGTNTCNGAYYTNGTNCAR AAYAARCCNCCNAARATHGARACNGARGARGAYCCNGTNCCNGTNGTNAARTTYYTNTGY GGNGCNGAYYTNYTNGARTCNTTYGCNGTNCCNGGNYTNTGGAARGAYGARGAYATHGAR CARATHGTNGGNAGYCAYGGNYTNGTNGTNATHAAYMGNGARGGNTCNGAYGCNGCNAAR TTYATHTAYGARTCNGAYGTNYTNTCNMGNTAYCARGARAAYATHYTNYTNGTNACNGAR TGGYTNCAYTGYGAYATHAGYTCNACNAARATHMGNMGNGCNATHMGNMGNGGNGARAGY ATHAARTAYATGGTNCARGAYTCNGTNATHGAYTAYATHAARCARCAYMGNYTNTAYGGN YTNCCNGAYATGATGAARATHGTNAARGCNYTNGARAAYCCNGTNTTYCAYTTYAARTCN YTNGAYGTNYTNGGNMGNYTNYTNYTNYTNGTNGCNGTNGGNTGYATGTAYMGN---ATH TGYTGYTTYAARAARYTNACNGARATGGCNAGYGTNCCNGTNYTNAARGAYMGNTGYCAY GTNMGNCAYGGNTTYYTNYTNCCNGTNGGNTCNACNCAYGAYGGNGARGARATGAAYGCN GTNTGYGTNGARGAYGTNATHTGYYTNTTYYTNGTNACNTTYGARYTNCCNCAYCAYCAY YTNGCNATGGGNCAYCCNCCNTGGAARTGGYTNTTYACNGCNATGGARTGYMGNACNYTN ATHCARGARAARTCNTAYCCNYTNGCNATGCARAARYTNCARGCNGCNYTNGARGCNTGY GARGARCCNCAYGARAARAGYMGNYTNYTNMGNYTNTTYGCNGAYTGYTAYTTYCAYYTN GGNTGYCCNCARYTNGCNATHCARACNTAYAARGAYGGNYTNCAYYTNGAYAAYAGYTGY GTNGCNATHYTNTAYGAYYTNGCNYTNGTNTAYMGNAGYYTNGAYYTNCCNGAYYTNGAR YTNGARTCNYTNAAYYTNTGYGTNATGGCNATGGCNGAYAAYGGNMGNAARGARAARGAY MGNMGNGTNCCNGTNATGGGNGTNGAYGARATGATHTGGGTNGTNAAYCCNACNACNCCN CCNGTNTCNTAYYTNATGTCNAARGTNATGTTYGCNAARMGNTGYYTNCARYTNAARMGN TTYCCNGARGCNGCNGARCARTAYTCNAGYYTNGTNAARATGYTNCARMGNGARGARCAY TTYTAYGARTTYGARCARCAYGARAAYGAYGAYAARYTNAAYATHGCNGARATHYTNGTN GARGCNTCNGARGTNYTNYTNYTNACNCAYCARTAYCARGARTGYYTNMGNYTNTGYGAY ACNACNCARCCNTCNYTN------------------------------------------ ------------------TCNGCNGAYGAYACNGTNGCNMGN---------AGYACNCAR GGNTTYAAYGAYTCNGCNATGGAYATHYTNTCNTCNTCNTCNTCN--------------- TCNCARGTNTCNCARTCNCARTCNCARTCNGAYTTYYTNCAYGGNTCNMGNTTYGGNCAY GAYAGYAGYTTYGAYCCNTTYGCNAGYCCNAAYACNTAYAARAARAARMGNAARAARAAR AAYACNAARACNCARAAYTCNTCNTCNGCNGAYYTNCAYACNGAYACNGCNGARMGNTGY GARGAYGGNGAYGTNGAYCAYYTNATGACNMGNYTNYTNYTNTGYAARGCNGAYGCNYTN GTNATGTCNGCNGGNTTYACNGAYCARACNGTNGCNTGYYTNCARCARGCNATHGAYATH YTNYTNMGNTCNACNCCNATGGARACNAAYCARGCNTCNTAYGCNCARCCNCCNGTNTCN AARMGNCARMGNATHAGYTCNGAYGGNAARGCNGCNAGYCARGARACNYTNTCNGTNTCN GTNTCNGTNGGNACNTCNMGNGAYGTN---TGGTCNACNCAYYTNGTNGCNACNGCNYTN MGNATGGCNAARGCNTCNTGGGARMGNAARMGNTTYCCNTCNGTNATHAAYAGYTGYMGN YTNGTNGARCARYTNGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GAY GTNAAYGARYTNTGYMGNATHAAYAAYYTNGTNAAYGGNATHCAYGCNCAYCCNTAYAAY TGYAAYGCNTTYATHGARTGYACNTAYYTNGTNACNAARATHATHCCNTGYCCNGCNAAY YTNTTYTAYAAYACNAARGTNCARACNTGYGAYAGYGCNGAYTCNGTNTGYCCNACNMGN GTNCCNCARCCNACNTCNGTNCCNACNACNCCNCCNACNGTNYTNGAYAAYATHTGYCAR CARYTNAAYYTNAARTCNGGNGTNTAYCCNCAYCCNTTYCARTGYGARAAYTTYGTNGAR TGYAAYGGNCARACNACNTTYATHATGGAYTGYCCNGCNAGYYTNTTYTAYGAYTTYCAY ACNCARAARTGYGAYGAYGTNCAYAARGTNGAYTGYGCNGCNAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AGYTGGCAR GTNGTNGCNGTNGCNACNAAYGCNGGNTTYGTNYTNMGNGARGTNYTNCCNTTYGAYCCN TCNGAYTTYCCNGARTAYCAYAGYGTNGGNTTYMGNTTYCARGAYAARAGYTTYAAYGTN ATHGGNGCNYTNACNCAYYTNTTYGARGARGGNGARYTNGTNGAYGAYTCNTAYGGNAGY GTNMGNGGNGTNGTNGTNGARAAYGGNAARGCNTAYTCNACNTCNMGNTAYGTNGCNTCN TGYYTNGCNMGNAAYYTNYTNCARGARCCNMGNAAYCCNATHTGYYTNYTNAGYCARAGY YTNGARCARMGNYTNAARGARAAYMGNATHCCNTCNCAYAARTCNTCNGCNTGGYTNGAR TCNYTNACNYTNACNCARGTNGAYAARGAYTGGAARAAYTGYGARAAYATGGCNAARYTN GCNCAYGGNGTNGCNGAYTCNGAYACNTGYGARGARAGYGARGARAGYGAYGCNAARATG AARGARAAYCCNAARTCNAAYGARGAYGTNTAYATHGGNGTNAARAARACNYTNTGYGAR GAYATHGAYAARACNGARACNGAYAAYGGNGGNAGYGGNGGNGAYGAYYTNCARGCNMGN TGYTGYGGNGGNGAYGCNTCNTCNCARGTNTAYCAYTGYMGNACNTCNYTNYTNGARAAY YTNCCNTAYYTNTGYGARGCNYTNACNGARTGYGGNAGYGGNAARMGNGGNAGYAGYACN ATGAAYTCNTCNGAYTTYTCNTCNGCNTCNCCNCCNYTNYTNATGGTNGCNTCNGGNCAR TGYGTNYTNCCNTGYGCNATHGCNCCNTGYACNACNCCNACNAARCAYGARYTNYTNATH YTNCAYAAYTCNCARTGYACNTTYGGNATHTCNCAYYTNCCNACNAAYAGYAGYTCNGCN ATGCARATHAAYATHGCNGGNATGGAYGARACNACNGCNGAYACN---------GAYGAY AARAARTCNACNAAYCCNYTNAARTGYGTNAGYTTYATHYTNAAYTCNMGNATHGGNGAY ------------------------AAYTAYTAYCAYGTNACNGTNATHAAYYTNGARCAY YTNGCNTGYAAYATGTTYGGNATHGAYGAYCCNMGNYTNYTNTGGTCNGTNAGYGARMGN TTYYTNAARCARTTYCARGTNGAYYTNTCNATHTGYMGNTTYTCNCCNTTYAGYYTNTAY CCNATGAARTTYGCNCAYCAYYTNAGYTTYTGGGARAAYGARGAYGAR---GAYTCNGAY CARTTYTAYGAYYTNTAYGARGTNGTNMGNAAYATHTCNGGNGAYYTNGTNACNAGYGCN MGNYTNACNGARGTNTAYGTNGARCCNGCNACNAARMGNMGNGGNMGNTGYTAYMGNYTN TTYTTYTGGTCNGGNGAYAARTGYYTNCCNTAYGTNACNTCNTGGAARYTNCARAGYCAR ATHMGNATHGARYTNGCNAARAGYYTNGGNATHCARYTNMGNAARACNTGYGCNGTNYTN CARGCNCARGGNAGYGAYTAYGAYAARMGNYTNAARAARYTNCCNGARACNGGNGTNGGN CAYGCNATGYTNGARTCNGTNCARGGNYTNCAYGCNGAYTCNYTNYTNGGNATHGCNTGY AGYTGYAARATHAARATHMGNYTNGCNYTNAGYGTNATHGGNATHGTNGTNGGNYTNTCN TCNGGNATHGTNTTYAGYATHCAYTTYAARAAYTAYCAYGCNGGNGTNTGGGGNGTNTTY TCNGCNYTNGTNGCNTTYACNGCNTTYTGYGTNACNGTNGCNTTYATHAARGGNGCNTGG GAYTCNAAYTAYCAYCCNYTNMGNGGNTTYATGYTNTCNGGNTGYTTYATHCARYTNGCN GGNGTNTGYGGNTTYGTNGCNTAYYTNGTNYTNGCNATHTCNCARCARCARCAYYTNACN GCNTAYGGNCCNGGNTTYTAYATHGCNTGYGTNTGGTGYTTYGTNACNTGGAARTGGGGN TTYYTNYTNYTNATGTAYTCNMGNACNTAYTAYTAYGCNTAYATGAGYAGYGCNGAYCCN ACNTCNTAYTCNGARCCNGARAARTGYGTNATGAARAARYTNAAYYTNAAYGTNAARATH GAYTTYGAYGCNCAYACNGTNGGNGGNGTNGCNAGYYTNTAYTTYGARAAYAARGTNGAY GCNYTNAAYAARYTNYTNYTNGAYGTNMGNGAYYTNACNATHAARAGYGTNAARYTNCCN GARAGYGGNGARAGYYTNAGYTTYAGYATHGAYAAYCCNGCNAAYGTNGAYTTYGGNTCN MGNYTNGTNATHCARYTNCCNGCNATHAARAAYAARAGYTTYACNGTNGAYATHGARTAY TGYACNTCNCARACNTCNACNGCNYTNGAYTGGYTNACNCCNAAYCARACNGCNGGNAAR AARCAYCCNTAYGTNTAYAGYCARTGYCARGCNATHCAYGCNMGNAGYYTNTAYCCNTGY CARGAYACNCCNGCNGTNMGNTTYACNTAYAARGCNCARGTNCARGCNCCNAARGARATH ACNGTNYTNATGAGYGCNAAYMGNGGNGARGTNACNCCNGTNGARGGNTGYAGYACNCAY CAYGTNACNCAYTTYTGYYTNGAYATHCCNATHCCNAGYTAYYTNYTNGCNATHGTNGCN GGNGAYYTNGARTCNMGNGAYATHGGNCCNMGNTCNAARGTNTGGTCNGARMGNGARTTY GTNGAYGCNGCNGCNTAYGARTTYGCNGARACNGARTCNATHYTNAARGCNGCNGARGAR YTNATGGGNCCNTAYGTNTGGGGNCARTAYGAYYTNYTNGTNYTNCCNCCNTCNTTYCCN TAYGGNGGNATGGARAAYCCNTGYYTNACNTTYGTNACNCCNACNYTNYTNGCNGGNGAY MGNTCNYTNGTNGGNGTNGTNGCNCAYGARGTNTCNCAYAGYTGGACNGGNAAYYTNGTN ACNAAYGCNAAYTTYGARCAYTTYTGGYTNAAYGARGGNCAYACNGTNTTYTTYGARMGN AARATHCARAGYAARYTNTAYGGNGARCCN---ACNMGNCARYTNCAYGCNTTYAGYGGN TGGACNGAYYTNAARCARACNATHCARGAYATGGTNGARMGNGGNGARGCNGCNTAYACN AARYTNGTNCCNGARYTNGTNGGNGTNGAYCCNGAYGARGCNTTYTCNAARGTNCCNTAY GARAARGGNTTYGCNYTNYTNCARCAYYTNGARACNYTNYTNGGNGGNCCNGARATHTTY AAYAARTTYYTNMGNGCNTAYATHGARCAYTTYMGNTTYCARTCNATHTTYACNGAYGAY TGGAARAARTTYYTNTTYGGNTAYTTYACNTCNGCNAARGAYCARGARAARYTNTCNTCN ATGGAYTGGGAYAARTGGYTNCAYMGNGARGGNGARCCNCCNTTYTCNCCNCAYTAYGAY YTNAGYYTNGCNCARCCNAGYCARGAYYTNGCNCARMGNTGGATHAARGCNGAYGARAAR ------GARCAYTTYTCNCCNGCNGAYATHAARGGNYTNAGYAGYGCNGTNGTNGARGAY TTYYTNATGMGNYTNGCNAARGCNGARCCNAAYATHCCNYTNTCNAARGTNCARCARYTN GARAARACNTAYGAYTTYAAYGCNGTNAARAAYTCNGARATHMGNTTYAARTGGYTNAAR YTNTGYATHCARGCNAARTGGAARGARGCNATHCARTAYGTNTTYAAYTTYGTNAAYGAR CARGGNMGNATGAARTTYGTNATHCCNYTNTAYAGYGAYATGAARAARTGGGARGARGGN MGNCCNYTNGCNTGGGAYAAYTTYGTNAARCAYMGNGARGARATGCAYAGYACNACNGCN AARAARGTNGARAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GCNYTNATHCCNCAYYTNGAR GGNGARAARYTNAGYAARGCNGCNATHYTNCARCARAGYATHGAYTAYATHGCNAGYYTN GARAARGAYAARACNMGNYTNCARATGCARYTNGARMGNACNACNMGNYTNYTNACNGAY YTNGGN---CARCARMGNGCNYTNGTNGAYCCNTTYYTNAGYGAYACNCCNCCNCCNCCN AARMGNAARAARMGNGAYACNGARTCNTCNGAYGARGGNGTNGGNTCNYTNTCNGAYGCN TCNGAYGAYAGYGGNATHGAYYTNMGNCARAARAAYGARGCNYTNAARCAYCARATGGAY MGNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGAYAAYCAYGAY GARGTNYTNGAYGCNYTNACNGCNTTYGGNAARGGNCCNAAYCCNCARGARATHCCNTCN ATHYTNGARCARTAYYTNAAYTGYGTNGCNAARAAYGGNGARACNYTNTTYCCNTGGTCN CARYTNAARCCNYTNGTNYTNMGNAARATGGARCARGTNATHTCNGARYTNMGNGCNACN YTNGCNGCNGARACNATHCCNACNMGNCCNAAYGTNGARAAYGTNMGNTTYGAYGTNATH CAYGCNMGNATHATHGAYTCNYTNCAYAARTTYAAYGGNGCNCCNTTYACNATHCARMGN YTNTGYGARYTNYTNATHGARCCNAARMGNCAYTAYAARMGNAGYGAYAARTTYATGMGN GGNYTNGARAARAAYGTNYTNGTNGTNAGYACNGTNGAYCCNTTYGGNMGNAARGTNGTN TGYGARTCNGGNAGYAARCCNATGGTNAAYGGN---ATHCCNGAYGTNAAYGGNTCNTCN TAYCCNTCNMGNGAYTCNGGNYTNAGYATHCCNYTNCCNCCNGTNCCNGGNTGGGTNACN ACNTCNATHGCNGCNGCNGTNGTNGCNGAYGCNGGNCCNCARGARGCNAARACNGARGAR GCNGCNACNGCNATGCARGTNAGYCARMGNGARAGYGAYGTNGTNCCNAAYGGNGTNTCN GCNGCNGTNACN------AGYTCNGARTTYGGNGAYCAR---GARGAYCCNYTNGCNGTN CARGCNGARGARGTNGTNGARGARACNGTNGTNACNATGGAYACNAGYGARGTNAGYTCN GTNGTNACNGAYGGNGGNGARGCNATGGCNGARGGNGGNGARGCNGGNGCNGCNGGNGGN GCNGARGAYMGNGARGCNTCNTCNTCNTCNTCNTCNTCNTCNTCNTCNTCNGARGARYTN TCNACNTCNTCNGAYTCNGTNGARMGNGCNAGYCCNTTYGGNGCNGCNGTNCAYAGYYTN AAYGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNAAYTGYATGGTNYTNAGYYTNTAYCCNGGNAAYGARGGNTAY ACNATHACNYTNCCNTCNMGNGCNGCNGGNGARTGYGARACNATGAARYTNCCNTAYGAR GARTCNGARATHYTNGARTAYGTNGAYGCNGCNCARYTNCCNCCNTTYYTNYTNGAYYTN YTNGARAARGTNCARGTNAAYYTNTTYTAYAGYGGNTGYATHGTNGTNGARGTNMGNGAY TAYMGNMGNTCNACNATHGGNTCNTTYGAYAGYCAYTAYGTNYTNYTNMGNCCNTCNTCN CARTCNATHYTNMGNGAYATHACNGCNATGAGYTGY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CARTTYGAYGTNTAYGCNGGNATHGAYGTNTTYGGNMGNGGNAGY CCNGGNGGNGGNGGNTTYGGNTGYGARACNGCNGTNAARATGATHTCNAARGARGGNYTN TCNTAYGCNATGTTYGCNCARGGNTGGGTNCAYGARGTNYTNGGNGCNGARTCNTTYGAY GCNAAYGARAAYAARTTYTGGMGNYTNYTNAARGAYTAYTTYCCNGTNMGNTCNGTNGAR ATHCCNTTYAGYTCNTCNTTYTGYCARGGNTTYGGNCARMGNCAYTAYYTNMGNGGNAAR GTNGTNAGYGARAARCCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TCNTCNCCNACNGCNTCNACNTCN ACNTCN---------CCNTCNACNTCNGCNGGNCCNTCNAGYGAYAARAARMGNAARAGY ACNCAYACNGAYGARGARTTYCARCARYTNATHAARCARTTYAARAARCARGAYGARGAR MGNATGAARATGCARGTNYTNGTNTCNAAYTTYTCNGARGARCARYTNAAYMGNTAYGAR ATGTTYMGNMGNGCNACNTTYCCNMGNGCNGCNATHAARMGNYTNATGCARACNATHACN GGNACNACNGTNTCNCARAAYGTNGTNATHGCNATGTCNGGNATHTCNAARGTNTTYGTN GGNGARGTNYTNGARACNGCNTCNGAYGTNAGYGARAARTGGGGNGAYTCNGGNCCNYTN CARCCNAARCAYATGMGNGARGCNGTNMGNATHYTNAAYGCNAARGGNATGYTNCCNACN ACNAARGGNAARAARTGYATGTTY------------------------GTNCARGTNCCN AGYGCNAAYAARAARGGNGCNYTNCCNGCNATHYTNTGYGGNGAYCCNACNAARGTNTCN MGNGGNYTNATHGTNYTNCARGARTGGTGGGGNATGAAYGAYCARATHAARGCNTGYGGN AARGAYYTNAGY---TCNCAYGGNAAYYTNGTNACNYTNGTNCCNGAYYTNTAYMGNGGN AARGTNACNACNGAYCAYGARGARGCNGGNCAYTTYATGGGNGAYYTNGAYTGGCARGGN GCNGTNGAYGAYATHMGNGCNGCNGCNCARTAYYTNAARAGYAARGGNGTNAARAARGTN GCNGTNACNGGNTTYTGYATGGGNGGNGCNYTNTCNATGGCNGGNGCNGCNYTNGTNTCN GARATHGAYGCNGCNATHCCNTTYTAYGGNATHCCNGGNGCNGGNYTNTGYGAYGTNYTN ACNATHAARATHCCNYTNCARTGYCAYTTYGGNYTNAARGAYGAYAARGCNGGNTTYTCN TCNCCNGCNGARTGGAARCCNYTNAARGARAARYTNGARAARCAYCCNAARACNYTNGAR TTYTAYGARTAYGAYGCNGGNCAYGCNTTYACNAAYAARACNGGNCCNACNTAYAAYCAR GCNGTNTGYGARCARGCNTTYGCNMGNATGTTYGCNTTY------------------YTN TGYTCNGTNATHGARATGGGNYTNGARATHACNCCNMGNGCNAARGARGARACNTGGACN ATHGTNAARGARYTNMGNAAYAARAAYCCNGTNGTNGGNACNTGGGGNMGNYTNAARGAY GTNAAYAGYTCNCAYGCNYTNGAYCAYGGNTGGAAYACNTCNCAYTGYTGYCARGARGTN TTYGCNACNYTNCAYATHGAYACNAARAAYGTNYTNTTYAGYCARAARAARCARGCNGTN CCNTTYTAYGCNTCNGGNYTNGGNATHYTNGARCCNACNMGNGGNGCNCCNAAYCCNGCN GARAARAGYCARCARCARCCNGTNCARCCNAAYYTNYTNGAYACNAGYAARCCNGAY--- GARCAYTCNAARAARGTNYTNGAYATHCCNCCNGTNGAYTTYGAYTGGGGNTCNAGYGGN YTNACNAAYCCNYTNAARGTNTTYAARGCNGARAGYTTYAAYACNGGNATGACNTCNYTN GAYTCNTTYTCNGAYGTNYTNCARAARAAYYTNGARCCNGCNAARGARYTNAGYGGNGAR GCNAARAARATHYTNTCNAARATGCCNAAYYTNGGNTTYATGMGNTCNAARGTNYTNATG TTYCCNATHAAR---------TGGAAYTCNGTNGGNAARYTNYTNAGYAARATHTCNTCN AGYGAYACNAGYAAYGTNTGYCAYGTNATHGCNGAYAGYTTYTGYMGNGAYAARGCNATH AARTCNGAYCARYTNATHTCNTCNTGGTCNYTNGARGARTGGTGGGARGTNMGNGCNGCN YTNYTNGCNYTNATGAARAARGCNGTNCARCARGAYTGGACNAARGAYCARATHAAYCAR CARYTNGGNTCNGTNGARGAYTCNTAYAARAAYGCNATHATGGARGCNATHTGYGTNCAR MGNTCNGCNYTNAARCAYAARYTNYTNGARAAYACNACNGCNATHTCNCAYGCNGTNYTN TCNGAYTTYGAYTGGAARYTNCARYTNGCNYTNTCNAGYGAYAARGTNTCNACNYTNCAY CARCCNYTNYTNTCNYTNGAYYTNGAYATHMGNCARGCNGAYGGNGARMGNAARCARGTN GTNGTNGARATGACNAARGARGARYTNGCNAARYTNATHACNTCNYTNGARGGNTGYAAY AAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYTCNGAYGTNYTNGGNGARYTNGGNCARGAR GCNAARATGATHATHYTNCARTAYTCNCARACNTTYAGYGAYAGYGARYTNTAYGARCAR CARGGNATHCARGCNGTNGGNGAYYTNTCNGCNCAYGCNAARGTNYTNGARGARMGNYTN CARTTYCARAARGARATGYTNTGYAAYMGNYTNAARATHATHACNAARCAYYTNAARAAY GARTTY---------CAYGGNCAYCAYGAYGCNGGNAARCCNYTNGARTTYGCNTCNGAR ATHCAYAAYAARGAYCAYATHYTNGARCAYYTNCARAAYGTNGTNTCNACNAARCCNAAR GAYCARYTNACNGAYGARGARYTNGARTTYCAYTAYTTYAARYTNCAYGAYTAYGAYAAY AAYAAYAARYTNGAYGGNGTNGARATHGGNAARGCNYTNACNCAYTTYCAYGAYGAYAGY TCNGCNGARGCNAAYAARGAR------------------AAYCCNCCNAARGTNTTYTCN GAYGAYGARATHTCNAAYATHGTNGAYTCNGTNATHGARGARAAYGAYMGNAAYYTNGAY GGNTAYATHGARTAYTTYGARTTYAARACNAARCARGCNGARACNAARCARTCNAAY--- ---------CARAARGAYCARCARCCNCCNATGGGNMGNGGNMGNTCNAGYGAYTCNGAY AGYGAYTAYTCNAARAARAARMGNAARGARAARMGNMGNGCNMGNTCNMGNTCNAGYAGY TCNAGYAAYTCNAGYAGYMGNCAYTCNACNAGYMGNMGNCCNAARAARTCNAARAARAAR CAYTCNTCNAGYMGNMGNTCNTCNACNAGYCCNTCNTCNCAYMGNCAYCAYAARGARMGN TCNACNMGNMGNTCNMGNTCNMGNTCNTCNGAYMGNMGNACNACNTCNMGN--------- MGNTCNMGNACNCCNGCNMGNMGNGCNMGNTCNMGNTCNAARTCNCCNTCNMGNMGNMGN TCNMGNTCNMGNTCNAAYTCNMGNTCNMGNGGNCAYMGNTCNACNAARGGNCAYGGNMGN CARMGNTCNMGNTCNMGNACNGGNMGNAGYMGNGARGTNTCNATGACNTCNTCNTCNAAY AGYAARCARGARAAYAGYMGNGAYAARACNACNACNTCNTCNTCNTCNTCNAAYCAYGCN AGYCCNGAYMGNAGYMGNAARGAYAARGARCARCARTCNGGN---------ATGACNTCN TCNGARATHGCNGARATGMGNATGMGNAARGCNYTNYTNGCNGCNGTNGCNACNGAYGAR MGNYTNAARCARCARGGNGTNGTNACNAAYGAYGGNGGNTCNTCNCCNACNCCNGCNCCN TCNYTNGCNACNATHACNGCNGCNTCNGCNTCNTCNAARCARTTYGCNGARTCNGTNGCN GCNATHGARATGGAYAARTTYGCNCCNGCNCCNTTYAARTCNTCNMGNACNGCNGTNAAR GARTCN---CCNAARGAR---YTNCARTCNAGYCAYGAYGARGCNATHTTYGGNTCNYTN TCNACNGTNGGNTTYACNATHAARCCNGAYCCNGAYAGYAARGTNGTNAAYYTNGAYCCN GAYTCNATHATHCAYCCNMGNYTNTTYTGYAAYCARGARGARAARATGGARMGNTGGATH GAYMGNYTNACNCARYTNMGNATGAGYAARYTNGARGGNGARGTNATGATGGAYGTNGTN AGYGTNGGNGGNATHGTNACNGAYATHTAYAGYTTYTGYCCNGCNTTYCCNAARCCNGGN GARAGYGTNAAYGCNMGNTAYTGYACNACNGGNTGYGGNGGNAARGGNGCNAAYCARGCN GTNGCNGCNGCNAARYTNGGNGCNAARTCNGCNYTNATHGGNAARYTNGGNGAYGAYATH TTYGGNAARATGCAYTTYGCNGGNTAYGARGARGCNGGNYTNAAYTCNGAYTTYGTNTTY ACNACNAGYGAYGCNGGNACNGCNYTNGCNTGYGTNATGGTNMGNGAYGAYGGNATGAAY TGYATHTCNGTNGCNTAYCARGCNACNYTNYTNYTNAAYGARGAYGAYATHCARAARGCN GARGAYATHATHAARTCNGCNAARGTNATHACNTGYCARYTNGARACNACNCAYGCNACN ACNYTNGCNGCNYTNAARATHGCNAARMGNCAYGGNGTNACNACNGTNYTNAAYGCNGCN CCNCCNTGYACNGARYTNTGYGAYGARATGTTYACNGTNTCNGAYATHTTYTGYACNAAY GARACNGARACNGARGCNTTYACNGGNYTNCCNGTNACNTCNGTNGAYGARGCNAARMGN GCNGCNACNTTYYTNYTNGARAAR---GGNTGYMGNTCNGTNATHGTNACNYTNGGNGAR GGNGGNTGYGTNTAYGCNAGYYTNGARGARMGNGARCCNAARCAYYTNCCNGCNMGNAAR GTNAARGCNGTNAAYAGYACN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GAYGAYGAYGARGARAARGARAARGARACNAARGARAARGARMGNGGNYTN ACNMGNGARMGNGARMGNMGNCARGARGARAARMGNCARMGNGARAARYTNGARATGYTN MGNGARCAR------------------AGYCARMGNGAYMGNGARAARGARMGNGCNMGN CCNAARATHTCNMGNTCNAARTCNMGNTCNGCNTCNCCNGTNGTNTCNMGNTCNMGNMGN MGNTCNMGNTCNMGNGARMGNGARMGNGARMGNACNAGYMGNGAYMGNTCNMGNGARMGN MGNAARGARMGNGARATHGARGARGARGARGARYTNTTYGARMGNMGNAARYTNGARAAR AARYTNMGNGARAARGARGCNGCNTAYCARGAYMGNYTNAARAAYTGGGARGGNMGNGAR MGNAARAARAGYMGNGARTAYGARAARGARAAYGARMGNGARGARGARMGNAARGTNGAR GARGGNMGNGARGCNMGNMGNYTNAARGARTTYYTNGARGAYTAYGAYGAYYTNMGNGAY GAYCCNAARTTYTAYAARGGNAGYGCNYTNCARMGNMGNYTNAARGARMGNGARAARGAR AARGARYTNGAYAAYMGNGAYMGNCARMGNGARAARGARGARTTYGARGARATHAARMGN AARYTNTTYGAYGARGGNCAYCCNGAYGCNGARACNGARGTNGCNMGNATGGARMGNGAR MGNGARGARCAYYTNCARCCNMGNYTNCAYYTNCARGTNYTNGARCCNCCNGAYCCNGGN CCNCCNATHGARGARTCNAAYTCNTAYGARGAYGARCCNAGYMGNGARGTNMGNCARCCN TCNCCNAARCARGCNYTNGARTTYTCNCARACNAARAAYGTNCCNGTNATHAAYGCNGCN CCNCCNCCNCARCAYYTNYTNGCNCCN------------------------GAYCARMGN CCNTCNCCNTCNYTNTCNACNTCNCCNATHTCNACNGAYTCNMGNGTN---AGYGCNCCN GGNYTNTGYATGGAYGARTCNTCNCARTCNTCNYTN------ATHAAYATGTCNACNYTN TCNTCNAAYAAR---GAR---CCNAARACNMGNACNACN--------------------- TCNAARAGYYTNGCNCCNAGYGTNAGYCCNGAYTCNAAYAGYYTNCCNAGYGTNCCNACN GTNTCNGAYGGNAARMGNAARAARYTNACNGTNGGNGAYGTNTTYAAYCARGAYGAYGAY GAYAGYAAYGARCCNAARAARMGNAARYTNATHCCNYTNGAYTAYGAYGAYGARAARTCN ACNCCNACNGARAARAARGGNGGNACNGCNGARGARAARMGNAARAARATHAARCARYTN ATHGARAAYATHCCNACNGCNAARGARGARYTNTAYGCNTAYACNGTNGAYTGGGARATH GTNGAYCARGGNYTNATGGAYAARMGNATHAARCCNTGGGTNACNAARAARATHGTNGAR TAYATHGGNGARGARGARCCNACNYTNACNGARTTYATHTGYCARAARGTNATHGCNMGN AGYACNCCNCARAGYATHCARAAYGAYGTNGCNATGATHYTNGAYGARGARGCNGARGTN TTYGTNGTNAARATGTGGMGNYTNYTNGTNTAYGARACNGARGCNAARAARYTNGGNYTN GTNAARYTNGAYYTNGARTCNTGGCCNATHCARAARGCNGARCAYTGGCCNACNACNGGN AARCAYATHYTNGCNCARTAYACNGAYGARACNATHGTNGTNTAYCARGCNTTYAARAAR TCNATHGCNGGNTAYGCNGTNGARAAYCARAARTTYGGNGGNAAYGAYTAYAGYTTYGAY MGNATGTCNTGGATHAARACNAAYTTYYTNTGGATGATGTAYMGNTCNGGNTGGGCNACN AARAARGGNCARGARMGNATHYTNGCNATHMGNATHAGYMGNGARGGNTGGGAYGARATH YTNTCNAARGCNTAYACNGCNTCNAARCARAARGCNGCNGAYATHCARACNAARGAYATH GARGTNMGNYTNCARTGGGAYCCNGAYCAYAGYCCNACNGGNAGYCCN---YTNCARMGN MGNGCNATHCARYTNGGNYTNAAR---ATGGGNAAYTGYGTNCAYMGNTGYTTYGGNGTN ATHGAYMGNMGNAARMGNTAYYTNCARTCNAARTAYACNACNGARCARAAYTTYTCNATH GARTTYGARAAYYTNATGGARGARGARCCNCARGAYGARATGTCNMGNYTNYTNACNGAY MGNGARMGNCARYTNYTNAGYACNAAYCARTTYGCNACNYTNGCNCARGAYCARMGNAAY GCNGAYACNGARATHGAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNMGNGCNTTYATHCCNAARMGNMGNCCNATHGGNMGNYTNGGNCARGTN GGNGCNAAYGGNMGNTTYTGYGTNGTNGTNGAYGCNGARAGYTGYYTNGAYMGNYTNTAY GGNGGNTAYTTYTCNGAYTGGGTNTGYGGNGGNCARTGGAAYMGNATGACNGCNTTYYTN ACNAAYYTNGTNCARGCNTGYCAYAAYGGNAAYATGGARYTNGTNGTNTTYTTYAGYGGN GCNYTNGARAAYCARAARATHAAYGARTGGATGTCNTAYCARYTNCCNCARMGNGAYAAR GTNMGNAAYGTNYTNMGNCAYATHGCNAAYAARGGNACNCCNCCNCCNAARATHTGGTGG AAYCARCCNGTNTTYYTNAARGARGCNYTNAARATGGCNYTNMGNCARYTNGGNGTNACN GTNGCNTGYTCNYTNGAYGAYCAYCAYCARGARGTNATHAARTTYTGYMGNGARCAYAAY YTNCARGGNATHATHGCNCARGARTCNGTNTAYACNATHTTYGAYCCNCCNMGNTAYTTY TCNTCNAAYAAYYTNAARYTNACNTAYAARGGNTCNYTNGARACNAARGARTAYATHATG GAYGARGTNGCNAARTGYATGAAYYTNAAYCCNAAYMGNTTYAGYGTNTTYGCNACNYTN YTNGGNAAYCAYATHYTNACNGAYGARGAYYTNGTNCCNTTYMGNGARYTNATGCCNGCN CCNGARGGNGGNAARCCNMGNAARCCNMGNGAYAARYTNGAYACNCAYATGATHAARGCN ACNTGYGAYTAYGTNMGNAAYYTNCARTCNGTNGARAAYYTNGAYACNYTNGGNAAYGAY GTNTTYAARYTNGCNAARACNAAYAARGCNGAYYTNYTNGAYMGNTTYAARAARAGYGTN AARTAYTAYGTNAGYGGNACNCARGARGGNTAYTTYAARCAYGTNYTNAAYMGNGGNCCN YTNATGTCNCARCCNGTNTAYGGN---GGNCAYCAYGGNCAYCAY------GAYGAYGCN MGNCAYCARGAYAAYGCNATGGGNGAYGCNAGYGCNAARMGNAGYCAYGGNYTNCCNCAR GTNTCNAAYGARATHYTNMGNGTNGCNATHGARMGNCAYCARAARGGNYTNATGAAYCCN YTNATHTAYCARGTNYTNACNCARGGNGARGTNAARYTNCCNTGYATHYTNGARGAYGAY AGYACNMGNGARYTNCCNAGYTAYATHGAYYTNTAYMGNCCNYTNMGNCARACNATHTAY TCNGTNYTNYTNAAYYTNAAYAARCARAARATHGTNCAYGARATHCARAAYAARGAYAAR GCNAAY---GARACNGGNGAYTTYACNGCNCARGTNAARGARTGGGTNGTNMGNMGNGGN TCNGGNMGNCCNACNTAYGAYGTNGTNACNGCNMGNCCNGTNGARTGGAARACNCCNAGY ATHCARMGNATGTGGYTNGGNCARCARGAYGGNGAYAARGARMGNMGNYTNMGNGCNTTY YTNACNACNATGATGAGYGAYACNAGYYTNATGYTNAAYACNAAYTAYATHCCNCARCAY YTNYTNGTNATGTGYTGYGTNYTNMGNTAYATGYTNCARTGYGGNMGNATHYTNCARMGN CCNGARYTNGAYGCNTTYYTNGCNATGGCNGTNTCNCCNYTNYTNMGNGAYATHCARACN ATGCARGAYYTNAARYTNCCNCAYATHATHCCNMGNGGNAGYCARYTNGCNTCNYTNTTY ATGGCNGGNATHGARACNGCNTGYATGGCNAAYGAYGTNTGYGGNGCNCCNATHCCNTGG ACNATGATHTGYCCNTGGYTNTAYATGGAYGGNAARYTNTTYCAYTAYAARYTNYTNAAR GCNAGYAAYAAYACNCCNYTNATHGAYATHTGYGAYGGNCARATGGARCARGTNYTNMGN GTNGARMGNATGMGNCARGCNATHYTNGARAAYYTNCAYGTNGAYTTYGCNAARCCNYTN ATGCCNGGNTTYTAYTAYCCNTAYCCNGGNGGNCCNCAYCCNATGGGNCAYATGCCNTAY CCNCCNGCNGGNGCNAAYMGNGGNATGGGNGGNCAYCCNGGNMGNCCNGTNGGNMGNGGN GGNMGNTCNCCNGTNGARGCNMGNGGNGGNCARYTNGARATHGCNGGNGTNGTNGTNGGN CARTGGGGNCCNAAYATGTCNGGNMGNMGNGGNMGN---GGNCARYTNACNCCNCARGTN ATGTCNGTNGGNCARMGNGGNATGTAYAAYGGNMGNGGNTTYYTNCCNCCNMGNGGNGCN TAYCCNTCNGGNTTYGGNMGNGGNAAYMGNTCNGCNMGNCCNATGMGNATHGTNGCNMGN CCNGGNATGGCNGAYGAYGCNGAYGTNCCNCCNYTNGARGAYATGACNGGNGTNYTNAAR AARGCNGARGCNATHMGNGARCARCARCARAARAAYMGNAARCCNACNAAYACNCCNGAY YTNAARAGYCAYGTNAARACNMGNGCNAARGTNACNAARAARACN---GCNGGNAAYAAY GTNAGYCCNGCNCCNGARAARCCNGTNGARGTNGTNCCNAARGAR--------------- ---------------------------ACNYTNATHACNAARACNAARCCNACNGGNGGN GCNAGYAGYGCNAGYAGYCARGGN------------ATGTTYGGNGGNATGAARAARGGN TTYYTNTTY---AGYAGYCCNAGYAARCCNAARTCNGCNTCNTCNTCNTCNACNGCNGGN AGYGCNGCNAARAAYAGYCARGGNAGYAGYAGYAGYAAYACNAAYATHACNGARATGACN ACNGGNGARGARAARACNAARGARGARATHCCNTTYATHAARGCNMGNGGNAAYGCNGAR TCNGGNYTNGCNYTNGAYGARGTNCARGARGCNATGACNGARGTNAARGGNYTNYTNGAY GAYCARGARTGGATHACNGARGAYYTNYTNGGNAARATHGARAARAAYGAYACNYTNYTN AARMGNTTYAGYGAYCARAARTTYATGTCNGCNYTNCARGARTTYCARACNAAYCCNCAR GCNGCNATGGARAARTAYAARGGNAAYACNGARGTNGARAARTTYYTNYTNGARTTYTGY GGNYTNYTNGGNGAYCAYTTYACNAAYYTNAGYAGYACNGAYTCNACNCCNACNAARAAY CARGGNCARGCNACNCCNAARCCNATGTCN------------------------------ ---TCNGTNCCNGTNGCNCCNACNGGNAAYGGNTCNTCNTCNTCNAARTCNGCNACNCCN AARATHATHGARYTNGGNAGYGGNGAYGARGGNGCNAARAAYACNTCNACNGCNACNGAR AARGARGGNGTNGTN---------------------------------GGNGGNAARGGN GGNAARTCNTCNGTNGCNYTNAAYMGNTCNGARGARAARAARCCNAGYCCNGAYATHYTN ATHCAYGAYGCNAARAAYMGNGCNGAYATHCARGARATHCCN---------------GCN GGNGGNGAYGAYGCNGTNMGNGAYGCNYTNAAYGAYCCNAARGTNATGGARACNYTNATG GAYGCNAARGTNATGAAYYTNATHCARGCNYTNMGNGARGAYCCNGCNAARGGNCARMGN ATHGTNGARGARGCNGAYAARAGYYTNAARGARAARATHMGNTTYYTNGTNTCNAARGGN YTNYTNCARYTNCAR------------AARCARAARCCNMGNAAYGARCCNTCNGCNYTN YTNACNAGYGCNGARAAYGGNGTNYTNTTYGGNYTNATHGGNTAYMGNTGYCARTCNYTN GCNTCNGCNGTNGTNCARGTNTAYYTNGCNGAYCCNCCNAGYMGNAAYAARTGGAAYAAR MGNTGYTGYGGNGTNGCNACNTTYATHAARGAYAAYCCNYTNAARTCNTAYTAYATHMGN GTNTAYGAYATHMGNGCNAARCARYTNYTNTGGGARCARGARYTNTAYAAYCARTTYAAR YTNMGNTGYCCNMGNCCNTAYTTYCARACNTTYGAYGCNGARGAYTGYGTNGCNGGNTTY AAYTTYGCNAAYGARGAYGARGCNGCNTCNTTYAARAAYGCNGTNGARGCNAARYTNAAY CARMGNCARGCNMGNMGNATGGARMGNAARAAR------ACNGTNCARMGNCCNAAY--- ------GCNCCNCCNTCNTCNGCNAAYAAYGCN---CCNAARTCNAAY---YTNGCNTCN TCNACNCCN---------AAYYTNTCNGCNTCNACNAAYAGYYTNTCNTCNATGGGNGGN ACNATHAARAARAAYAARGAYAARAAR---------GGNAARAARTCNAARYTNACNAAR GARGAYATHGGNACNCCNACNGAYTTYMGNCAYGTNAGYCAYGTNGGNTGGGAYCCNGAR ACNGGNTAYGAYATGAAYAAYYTNGAYCARGAYYTNMGNTCNATHTTYGAYGARATHGGN YTNAAYGARGCNCARYTNAARGAYAARGAYACNGCNAARTTYATHTAYGAYTTYATHGAR CARAARGGNGGNATHGAYGCNGTNAARAARGARGTNGCNGCNACNAAR------TCNMGN CCNCCNCCNCCNCCNCCN------------GTNGGNGGNGCNCCNCCNCCNCCNCCNGCN MGNGGN---------CCNCCNCCNCCNAGYMGNGGNGGN------CCNCCNCCNCCNCCN AGYMGNAAYAGYGCNCCNCCN---CCNCCNGTNCCNMGNGGNCCNCCNCCNCCNAGYMGN GGNCCNCCNCCNAAYMGNGGNGGNCCNCCNCCNCCNCCNATGGGNAARCCNCAYGGNGGN GCNCCNCCNCCNCCNCCN---GGNGGNCCNCCNCCNCCN------------CCNCCNCCN CCNCCNCCNGTNGGNGGNGGNCCNCCNCCNCCNGCNGGNGGNCCNCCNGCNCCNCCNCCN ATGAARCCN------ATGGCNAAYYTNYTNGGNGARAGYMGNYTNYTNACNAARAARGTN TTYGAYGARACNYTNAARCCNGARAARGAYGGNGAYAAY------ACNACNAGYGCNMGN GARACNYTNGARGGNAARGTNGTNTGYYTNTTYTTYTCNGCNTCNTGGTGYACNYTNTGY CARCAYTTYGTNCCNAAYYTNAARGARGTNTAYTCNGAYYTNGTNCARMGNAARAGYCCN ATHGARATHGTNTTYYTNAGYTTYGAYAARACNGARGARGAYATGATGAAYTAYTAYMGN GAYAARCAYGGNGAYTGGYTNGCNGTNAARTTYGGNGAYCCNYTNAARCARGARYTNGCN GARMGNTAYTCNATHAGYGTNATHCCNAARYTNATHGTNATHCARCCNGAYGGNGARATH ATHAGYAGYAARGGNMGNAARGAYGTNCARGAYMGNGGNGTNGTNTGYATGMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------YTNGAYATHGCNGGNATGMGNAARCCNTAYAARGGNCAR CARGARGTNTTYGAYGTNAGYCARYTNGTNTCNACNGCNCCNTTYGAYCARTTYGGNMGN TGGTTYGARGAYGCNAARAAYTCNCCNGGNATGGCNGARGCNAAYGCNATGGCNYTNGCN ACNGCNTCNAARGAYGGNATHCCNTCNGTNMGNATGGTNYTNATGAARGGNYTNAGYAAR CARGGNATHGAYTTYTAYACNAAYTAYCAYAGYMGNAARGCNCARGARYTNATGGARAAY CCNCARTGYGCNYTNATGTTYTAYTGGGARCAYYTNAAYMGNTCNGTNMGNATHGARGGN AARGTNGARAARYTNAGYCARGARGARTCNGTNACNTAYTTYCAYTCNMGNCCNMGNTCN AGYCARATHGGNGCNTGYGTNAGYGARMGN---CARAGYTCNGCNATHTCNTCNMGNGAR GCNYTNGAYAARMGNAAYGARGAYYTNCARTCNAARTAYAGYGAYGAYAGYGTNCCNATH ACNAARCCNGAYTAYTGGGGNGGNTTYMGNGTNGTNCCNCAYMGNTTYGARTTYTGGCAR GGNCARACNAAYMGNATHCAYGAYMGNATHGCNTTYMGNAARCCNGTNGCNGGNGARACN ATHGAYCCNACNGTNACNTTYGARGGNGARGAYGGNTGGGTNTAYGARMGNYTNCARCCN CARAGYCAYATHGARMGNATGCCNACNATGATGGGNMGNCARGCNMGNYTNCARTTYCAR TCNAARYTNACNGGNTTYGAYGARGCNYTNGARAARGTNYTNAARGCNGCNAGYGARCAR CARTGYATHACNTCNGAYGARGTNGTNTCNTAYGCNGTNYTNTCNGTNATHAARGAYCCN CARCAYACNAGYAAYCCNTGYTTYAAYATHCAYCAYAARTGYMGNGTNAAYTCNTCNATH GAYATHYTNTCNGCNGAYYTNMGNGTNGGNCCNTGGAARAARMGNCARCCNGARGTNACN GARMGNGTNTAYYTNMGNGCNYTNATHMGNGARYTNGARTGGAARGGNTTYACNGTNACN TTYACNAARACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGAYNNNCCNNNNNNN NNNNNNCCNAAYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCNNNNNNNCCNYTNNNN NNNGAYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGNNNNNNNNNNNNNNNNYTNGGN NNNNNNNNNNNNNNNNNNCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCNNNNNNNNNN NNNAARNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCNNNNAAYNNNAAR NNNNNNNNNTGGNNNCCNCARAAYGAYYTNNNNNNNNNNNNNAANNNNAARNNNTTYNNN NNNCAYNNNGGNNNNAAYGGNCARNNNGARNNNNNNNNNCAYGGNNNNCCNATGNNNNNN NNNCCNNNNNNNNNNGANCARNNNTAYAAYNNNNNNMGNNNNNNNNNNNNNNNNTAYGGN NNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGANGARYTNTAYAARATHATGTCNGARATH ATHAAYAAYGARACNTAYTCNAARAAYATHAARAARTGYTCNGCNATHATHMGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYTCNTTYTCNYTNGTNAARTCNGCN GCNTTYGTNACNGGNGTNGGNACNTGYAGYTTYYTNAGYGCNATGATHTGGAAYTAYGAR AAYGTNMGNAARGTNTAYAARGARATG---------GGNACNGARAARGCNCARMGNCAR MGNTAYATGAAYGARAARATGTTYGGNTTYMGNGARCAYATGAAYGCNATGTGGAARAAY YTNGAYTCNACNACNAARYTNACNGTNGGNATHATHGCNGCNAAYGTNGCNGTNTGGGCN YTNTGGAARGTNCCNMGNTTYCARCAYAARATGGTNCARTTYTTYTCNTCNGCNGCNGCN CAYCCNMGNYTNTCNATGGTNYTNAGYAGYTTYAGYCAYATHAGYYTNTTYCAYYTNGGN GTNAAYATGTAYGTNYTNATGTCNTTYGCNCCNATHGCNATGMGNYTNTTYGGNCAYGAR CARTTYTAYGCNTTYTAYATHAGYGCNGGNACNATGTCNGCNTTYACNAGYATHYTNTGY CARMGNYTNYTNAARMGNCCNYTNTCNATHTCNGTNGGNGCNTCNGGNGCNATHATGGGN YTNYTNGGNGTNACNGGNATHGTNTAYCCNCAYGCNCARYTNCARGTNGCNTTYGTNTCN GARATHATHCCNCAYTCNTTYTCNGCNGARACNGGNATHAARGCNATHATHYTNTTYGAY YTNYTNGGNYTNTTYATGGGNTGGAARGTNYTNGAYCAYGCNGGNCAYYTNGGNGGNATG YTNTTYGGNGTNYTNTAYGCNAARTAYGGNAAYAARYTNATHTGGGGNAAYMGNGARTCN GTNGTNAARAARTGGCAYGAYTTYMGNGGNAARCCNAARACNACNGARGARYTNCARYTN GARGARATHGCNAARAARAARCARGARYTNGCNGARAARMGNAARGCNTAYGARGCNGTN TAYAARAARGTNATHGCNAARGGNAARCCNGTNGCNATGAARTCNTCNCARGCNCCNACN ATGCCNCARGARTTYCAYTTYCARTCNGAYCARMGNATHAARAARGTNGCNGARGCNACN GARGARAARACNATHAARGAYTTYGCNAARACNYTNMGNTCNGCNYTNCCNAAYACNACN AARGGNAGYGGNGCNTGYACNMGNCCNAARCCNTTYAAYYTNACNAARAGYCCNAAYYTN ATHACNGCNGARAARTAYAARTCNACNGCNGAR------------------GARMGNTTY MGNTCNACNTCNCARAAYACNTCNAGYTCNMGN------MGNCCNAARTCNCCNGGNYTN ACNATHCCNAARACNCCNAAYYTNAGYACNAARGGNMGNACNMGNTCNATGGTNMGNYTN ACNMGNGARGARGARGARGARYTNGAYTAYGAYCARCAYAARAARCARCARTTYAARGCN CAYCCNGTNAAYCAYAARATHYTNAARGARGCNCARGTNGGNGTNCCNAARATHCCNGCN AARGCNCCNACNGCNGTNAARGARTTYAAYYTNCAYGTNGGNACNTCNCAYCCNGTN--- ------------AARTCNTAYGARGARGARACNTGYGARTTYCAYGCNCAYGCNGTNAAY MGNAARATHYTNGARGGNACNACNGGNATHAARCCNGCNGARAARAARGCNYTNACNATH CCNGARTCNCCNGCNTTYTCNYTNMGNGGNMGNYTNMGNMGNCARGARCCNGTNAARCCN CARGARGARATGMGNCARAARGTNTTYGCNAARCCNCCNCCNCAYATGGGNGTNCCNTTY AARCCNCARTTYGARCAYMGNTTYACNGTNCCNAARCCNTTYGCNGTNGARGAYCAYAGY AARGARATGYTNAARAARAARGARGARAARATHAARAARGTNYTNGARGARGARAARAAR GCNMGNGARTTYCAYGCNTCNATHYTNCCNAGYGAYAGYCCNGAYCARYTNCCNCCNAAR AARACNMGNCCNGTNACNGCNGTNGARCCNTTYMGNYTNACNGTNGAYGARMGNGGNAAR AARTAYCAYGARGAY---ATGATGAARCAYATHGARGARGARGARGAYCARGCNMGNACN AARGCNCARTTYCAYGCNTCNTCNAAYAARGTNATHCAYAARGCNCCNTTYGTNCCNGAR AARTCNACNAARCCNYTNACNGARATGAGYAGYTTYACNYTNAAYTCNGAYCAYMGNGCN GTNAARMGNGARGARTTYAAYCARCARYTNAARGARCAYGARGCNATGATHGARGGNGTN AARMGNCARMGNGARGARMGNAARGARAARGARGARCAYGARGCNGTNTCNCARYTNMGN CARAAYATGGTNTCNAARGCNACNGCNATHAARAARTAYAARGTNYTNGTNCCNCARCCN AGYGAYAARCCNYTNACNGARGCNCARTCNCCN--------------------------- ---------------CAYGGNGGNGCNAARGAYGAYCCNCAYGGNGGNGTNCCNATGGGN ATHCCNAGYAARTTYTGYGAYGAYGGNAARAGYTAYACNGCNATHGAYTGGGAYTCNGCN TCNATHGARGARCAYACNTGYGAYGGNGARACNATHTCNGGNYTN------GCNAARAAY ---------AGYTAYAGYAGYTGYGARACNGARGCNAARMGNCCNATHCAYGTNTGYTAY CCNGARGTNATHMGNTAYGAYGARGAYATHCCNACNAGYGGNCAYCAYMGNCCNYTNTGG CCNAARTAYGGNGARTAYMGNTAYGTNCCNCCNCARMGNTGGYTNCAYTCNYTNGARCAY GGNGCNATHGTNTTYYTNTAYCAYCCNTGYGCNGAYCCNAARCARGTNGCNATHTTYAAR TCNATHGCNAARCAYTGYYTNMGNMGNCAYATHATHACNCCNTAYAARMGNATHCCNAGY CCNAAYATGTTYGCNYTNGCNTCNTGGMGNTGYAARYTNGTNATGACNCARCCNGAYATH GAYAARATGGTNMGNTTYATHMGNACNCAYGCNYTNCAYTCNCCNGARMGNTCNGTNCAY ACNGAYGGNCARTAYAGYATHGGNYTNACNCAYCAYGCNAARATGGTNTCNGAYYTNGCN GARACNGTNYTNTGYCCNGGNYTNTCNCARATHGARAAYGARCCNTTYGAYTCNAGYAAR AARMGNMGNATHGAYGCNGTNYTNGTNCCNGAYYTNGAYGAYGCNATHYTNMGNATHGCN MGNATGMGNAARGCNCARGTNYTNAARTGYAARTGYGARGCNMGNAAYATHGTNACNAAY ACNGTNAARTAYTAYAGYAAYGTNACNGTNGARTGYGARCCNGTNGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TCNTCNGAY GGNYTNGAYGGNGAYMGNTCNTGGGARMGNMGNACNACNACNTTYAARCCNCCNGTNCCN GTNGGNCARATHGAYGAYCCNTCNGGNCARAGYTCNCARAARGCNTCNTGG--------- ------TCNAGYYTNTCNGGNGGNAAYCARCCNGGNAGYATGGARGCNYTNAARAAYATG YTNTTYAARYTNCARAARGARGARAGYTCNGTNAAYAAYGCNAGYACN---------TCN GCNGTNCCNGGNYTNCARGAYTAYGAYTTYGAYACNGARCCNGGNGGNCAYTCNYTNGAR AARGCNYTNCAYCAYYTNGAYMGNYTNAARACNGCNAAYGAYTCNCCNGAYAGYTCN--- ---ACNGTNACNGTNAARAARYTNGARGAYGARTCNGCNTTYCCNTAYGCNGGNMGNGAR GGNCARGTNGCNTGYAGYGTNTCNAAYCARGTNTAYGTNTTYGGNGGNGTNGARCARGGN CARGGNGAYGARCCNAARGARACNAAYGARYTNYTNGTNTTYGAYYTNGCNTCNCARAAR TGGTCNAARCCNACNGTNCAYGGNAAYCCNCCNGCNGCNMGNTCNGCNGCNTCNYTNGTN GCNGTNGGNACNAARYTNTAYYTNTTYGGNGGNYTNAGYCAYATGTGYGGNTGGTTYGAY GAYGTNCAYGTNTTYGAYACNGCNACNAGYACNTGGTCNATHYTNGARACNGAYGGNTCN AARCCNMGNGCNMGNGAYAARYTNCARGCNGTNACNATHGAYAGYAAYATHTAYTAYTTY GGNGGNTTYGGNCCNATGTCNGAYGARGCNGARGTNGAYGAYYTNGCNGGNGAYGAYGAY GAYGAY---GAYGARTTYGARGAYATHCCNGARAGYCARCARCARGAYGCNGCNAAYTTY GGNTGGTTYAAYGAYYTNTGGGTNYTNGAYACNYTNACNYTNAARTGGTTYCARCCNATG CARATGAAYYTNGGNGTNCCNACNCARMGNGCNGCNCAYGGNATGTGYGCNATHGGNMGN AAYATHATHATHTTYGGNGGNMGNGAYATHGCNGAYMGNCARAAYGAYGTNCAYATHTTY AAYATHGAYTCNMGNAARTGGGAYACNGARYTNAARATHTCNGGNGTNYTNCCNGCNCCN MGNTCNTTYCAYACNYTNACNGCNGTNGGNAAYAARGCNGTNYTNTTYGGNGGNMGNGGN MGNAAYAAYAAYCAYTTYGGNGAYTTYGARGTNYTNGAYATGGAYACNAARGARTGGAAR CARGTNTCNATHGARGGNTAYAARCCNCCNGCNMGNGGNCARCAYTGYGCNYTNACNGTN GGNGAYACNTTYGTNGTNTTYGGNGGNTCNGGNAAYTTYAGYCCNGARATHATGCARTGY CARACNTTYYTNAARGAYACNTTYTTYATHAARACNGAYGAYTTYTGYCARGGNTCNAAY AARACNAAYGGNGGNTCNACNATHACNTAYMGNACNATHGGNGGNATHYTNGAYTTYTGG GTNTTYACNGGNCCNACNCCNGAYGAYGTNATHAGYCARTAYACNGCNGTNATHGGNMGN CCNATHATGCCNCCNTAYTGGGCNYTNGGNTTYCAYYTNTGYMGNTGGGGNTAYGGNGGN TCNGARGGNATGAARMGNGTNGTNGAYMGNATGMGNGCNGGNAARTTYCCNTAYGAYACN GAYYTNCAYAAYAAYAGYCARCCNGGNGGNTAYAAYCCNTAYGAYTCNGGNAARGTNTGG CCNGGNACNACNGCNTAYCCNGAYTTYAGYAAYCCNGAYTCNTAYGGNTAYTGGYTNGAY YTNGCNAGYGGNTAYMGNAARCARATHCCNTTYGAYGGNATHTGGGTNGAYATGAAYGAR CCNTCNAAYTTYGTNGTNGGNTCNACNAARGGNTGYCCNGCNAARAAYAARTAYGAYTAY CCNCCNTTYGTNCCNGGNGTNYTNGGNGGNAAYYTNMGNGAYAARACNATHTGYCCNTCN TCNCCNCARAAYYTNTCNATHCAYTAYAAYYTNCAYAGYYTNTAYGGNCAYTTYGARATH GTNCARACNAAYAARGTNYTNACNGARYTNACNAARAARMGNCCNTTYACNGTNAGYMGN TCNACNTTYGCNGGNTCNGGNAARTTYGGNTTYCAYTGGYTNGGNGAYAAYAAYGCNGAY TGGAAYAAYATHTAYTAYTCNGTNCCNGGNATHYTNAAYTTYAAYATGTTYGGNATHCCN YTNGTNGGNGCNGAYATHTGYGGNTTYATGGGNTCNACNACNAGYGARYTNTGYACNMGN TGGACNCARYTNGGNGCNTTYTAYCCNTTYATGMGNAAYCAYAAYACNAARGGNGCNCCN GAYCARGAYCCNGCNAAYTTYCCNAARTCNGCNCARGAYGCNATGMGNAAYGCNATHACN YTNMGNTAYACNYTNYTNCCNACNYTNTAYTCNYTNYTNTAYAARAGYCAYATHAAYGGN ACNGGNGTNGCNMGNCCNYTNTTYTTYCARTAYCCNAARGAYTCNAARACNTAYACNATH GAYMGNCARTTYYTNTGGGGNGAYTCNYTNATGATHTCNCCNGTNYTNACNCARGGNGCN ACNACNGTNGAYGCNTAYTTYCCNAARGAYGTNTGGTTYGAYTAYGCNTCNGGNAARMGN ATGACNGCNTCNGGNGCNTCNGTNAARYTNGAYGCNCCNYTNGAYAARATHAAYGTNCAY ATGMGNGGNGGNAGYATGGTNGTNACNCARGGNGCNAAYGTNACNACNACNYTNAGYMGN AARAAYCCNTTYGGNYTNGTNGCNGCNYTNCCNAAYACNACNAAYCCNAAYTTYCARTGG TAYTGGGAYGAYGGNGAYTCNYTNATGCARGAYGGNCARGGNAAYYTNATHTCNYTNACN GCNGCNAARACNAAYAARGGNGGNTAYATHAAYGGNGTNGGNTTYGARACNTCNATGATG YTNGGNACNGTNMGNGTNYTNGGNGTNGAYGCNAARCCNAAYAGYGTNACNATHAAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGYTNACNATHACNGAYTTYATHAAYATHYTNAARGARTAYTAYAARTGY CCNGARACNMGNATHGARGARYTNGARGAYCAYAARATHGCNACNTGGMGNGAYYTNYTN AARGARMGNCARMGNCCNTTYGTNTCNATHTGYCCNGAYGAYAGYYTNTTYGARGCNGTN AARACNYTNGTNGAYAGYCAYGTNCAYMGNYTNCCNGTNATHGARGARGGNACNGGNAAY GCNYTNTAYATHYTNACNCAYAARMGNATHYTNMGNTTYATGCAYYTNTAYTTYAARGAR YTNCCNCAYCCNMGNTAYATGAARAARTCNATHAARGARYTNGGNATHGGNACNTAYGAR AAYGTNATHACNGCNAGYCCNGAYATGACNYTNATHAARGTNYTNAAYYTNTTYTCNAAY CAYMGNATHTCNGCNYTNCCNGTNGTNGAYTCNACNTCNGGNAARATHATGGGNATHTAY GCNAARTTYGAYGTNATHAAYYTNGCNGCNGARAARACNTAYAAYAAYYTNGAYATHACN YTNCARGARGCNYTNAAYMGNMGN---TTYGAYAAYCARCARACNGGNGARAAYGTNGTN TCNTGYYTNTCNTCNGAYTCNYTNGARGAYGTNGTNAAYAARATHGTNAARGCNGARGTN CAYMGNYTNGTNGTNGTNAAYGARAAYGGNGGNGTNGARGGNATHATHTCNYTNTCNGAY GTNYTNAAYTAYACNGTNYTNMGNCCNATHGARCARGTNTCNGAYGARGAYTTYGTNGTN YTNGGNACNCCNYTNCCNGARYTNGAYGARMGNGARGGNCCNAARAARCCNATHACNGTN CARGAYYTNACNGCNAARGAYAARGARGGNMGNMGNMGNTTYCAYGGNGCNTTYACNGGN GGNTTYTCNGCNNNNTAYTTYAAYAGYGTNGGNTCNAARGARGGNTTYACNCCNTCNACN TTYGTNTCNTCNMGNAGYCARAARAAYGAYGARTCNAAYTTYTCNMGNCCNGARGARTTY ATGGAYGAYGARGAYYTNGARGARCAYGGNATHGCNCCNMGNAARTTYGCNACNGCNAAR AAYTAYACNTCNGARGARMGNAARMGNAARTTYGARGAYYTNACNAARGGNYTNACNAAR TCNTCNCCNYTNGAYATHGGNGCNGCNYTNGGNGAYYTNTTYGTNCCNGARTAYYTNCCN ATHGGNATHAARYTNYTNMGNAARATGGGNTGGMGNGARGGNCARGGNGTNGGNGCNMGN GTNAARAARAARAGYAARMGNGGNAARAARACNGGNAARGCNGGNGGNAARAARATHTAY GGNTGYGCNYTNCCNCCNTCNGAYTCNGAYAGYTCNGAYTCNGAYTCNTTYGTNCCNGCN AAYATGAGYGAYYTNACNTTYGCNCCNTCNGAYGTNACNCCNATHTCNYTNAGYGCNAAR GAYGAYGTNAARGGNYTNGGNTAYMGNGGNYTNGAYCCNTCNYTNGCNYTNCCNGGNTCN CAYATHAAYYTNTTY------CCNGTNMGNGAYAARAARMGNGGNCARGGNATHAARGGN CAYGCNTTYGGNGTNGGNGCNYTNGARGARGAYGAYGAYGAYATHTAYGCNCARGAYAGY ATGGCNAAYTAYGAYATGACNATG---MGNGAYGGNGAYGAYMGNGAYACNACNTTYGGN TGGACNGCNCCNMGNGCNCAYGGNAARCARACNGTNCCNGTNTCNTAYGTNGGNAARYTN YTNGARGGNTTYTGYYTNTCNTCNAARCCNYTNCARCCNGGNAARAARTTYCCNCCNCCN AAYYTNCCNTCNAAYTTYAARCCNTAYCAYTGGTCNMGNMGNMGNAARATH------GAR GAYACNGCNGCNGGNAAYMGNAAYCAR---ATGTCNGCNGTNGAYMGNGGNYTNYTNYTN GGNGARACNCCNGTNATGGAYTCNGTNTTYGAYYTNGTNAGYGCNAARGAYAARTCNMGN ATHAGYCAYACNCARGARGCNATHGCNATGACNAARTCNYTNGCN--------------- ---ATGAARCARTCNTCNCARCARGCNGAYACNACNACNCCNCCNTCNAGYGTNAAYAAY GARGARACNAARCCNTCNACNACNAGYAAYGAYGCNMGNGCNTCNAARTTYATGTCNMGN TTYACNCCNGCNAAYGAYACNATHGCNGAYTTYGCNTCNACNTCNAGYGAYAGYGCNGCN ACNAARCCNCCNYTNTTYCARGGNTCNYTNAGYYTNCARCCNTTYMGNAARGAYCCNCCN AARCARGCNMGNTAYGAYGTNTAYGTNGCNGCNGTNAARCARGGNGTNCCNGARCCNTAY GGNGARGTNTCNAGYAGYTTYATGACNGARTGGGARMGNGCNAARGARMGNGAYGARTTY AGYMGNTCNGCNMGNYTNTTYMGNCCNATGTCNGCNATGATGGCNACNMGNTTYGTNGAR GGNTCNATGYTNGAYGAYAARAAYCARGAYTCNAARAAYAARGAYACNGARGCNCCNTCN GAYGARGTNAARGCNGCNGARATGAARATGTTYGGNAARYTNACNMGNCARGARTTYGAR TGGCAYCCNGAYAARYTNATHTGYMGNMGNTTYAAYGTNCCNAAYCCNTAYCCNGGNTCN GAYATHATHGGNYTNCCNGAYGTNAARMGNGAYAARTAYTCNATHTTYAAYTTYYTNTCN GTNGGNGAYTTYMGNCCNAGYGARACNGCNCAYATHCCNGARCCNGAYGTNTCNAARCCN GCNGAYAARGARCCNTCNAARGAYGAYAGYYTNAARMGNCCNGGN------AARAARAAR GCNACNYTNGCNTCNATHTTYAARGTNYTNGAYGAYCCNGAYTTYCAYAAR---YTNCCN GARGARGCNAARACNGAYATHYTNGARCARGGNGCNGTNGARACNYTNGARAARGARGAR GARGAYGAR------------------------GARGARCCNGAYGAYGAYYTNTTYMGN GCNATHTTYAARAAYTCNGAYTCNGARGAYTCNGARGAY------GARAARGAYGARGAY ATGAGYGAYGAYAARGAYAAYGAYGAYGARGARGARGARGCNAARAARGAYAARGAYTCN TCNGTNATHCCNATHCCNAGYGARTCNGARACNAAYGGNGCNMGNCARATH--------- GARCARGCNGGNACNTCNAAYMGNYTNCCNACNGAYATGGARGTNGARAARTCNGAYAAY GGNCARCCNTCNGARTCNGARAAYACNGCNACNGARGGNAAYGAYACNCARCAYGTNAAY GARCARTCNGCNGTNAARYTNMGNMGNTTYGARTCNMGNTGGGGNTCNAARTCNGTNTTY AGYGTNYTNGAYGARGTNAAYGARGARACNMGN--------------------------- ---MGNCARAARGARACN---GARATHAAYGARGTNTCNGAYGARTAYGGNCCNGCNYTN CCNCCNTCNGTNGCNTCNACNCCNCARACNTCNACNATHCARGAYGGNGGNGCNAARAAR GARYTNAARGARGARTCNMGNCAYMGNCCNMGNAGYCAYCARAARGARAARCAYAARCAY AARAARGARAARAARAARAARTCNAARCAYAARAARGARAARAARCCNAARAAR---AGY AARAARTCNTCNAARTCNAARAARCARMGNGCNGAYAGYTCNGGNAGYGAYGGNGAYACN GAYTCNAGYCARGARTCNGAYGTNTCNGAYGGNGARYTNATHCARMGNTGGAARCARGTN TCNAAR---------------------GTNTGYGTNCCNGCNAARCAYGCNCAYATHGAR MGNACNAARYTNAARMGNGARAAYYTNTGGGAYGARGGNMGN------------------ ------------------------------------------------------------ ---------------------------------ATGYTNCARAARTTYCARAARYTNCAY YTNCCNCCNTCNGCNGARGCNYTNYTNTTYGARGTNCCNCAYAARTGGGARAARTAYGGN GAYYTNGTNATHTTYCCNTCNTCNGCNTTYAARTCNCCNTAYTGGCAYCARYTNGGNGAR GARYTNTGG--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------YTNACNATGATGAARGARGARCAYATGYTNMGN ACNAARGTNGAYAAYYTNAARGCNGARAARACNGARMGNATGACNAARTAYAAYGAYYTN CAYACNMGNGAYGARGARYTNTGYMGNGTNYTNGCNGARATHCCNTAYTAYGTNCCNTCN GGNAGYGTNCCNACNYTNCARCARYTNAARGARYTNGARGCNCAYGTNAAYMGNATHCAR ACNGARAARGAYAARMGNAGYGCNGARTTYAAYGAYATGMGNAGYAARATHTGYGGNYTN TAYAAYGARATGGARGCNGAYCCNGARACNTCNTTYGCNCAYAAYGTNGTNTGYGAYGAY GTNGAYAAYTTYACNYTNTCNGTNACNAARATGGAYGARYTNMGNTCNYTNCARGARGAR YTNGARCAYAARAAYAARCARATGACNCARGARACNGARGAYYTNTGGGAYMGNYTNAAR GCNYTNTGGAARMGNYTNGARACNCCNGARATHGAYCARGARGGNTTYAGYYTNAAYAAR TTYGGNCAYGGNAARAARGTNGTNTCNGARYTNAARGCNGARATHGTNGCNTGYGARGAR YTNAARYTNCARAAYATHCARAARTTYATHAAYGGNATHMGNACNGARYTNGTNTCNTGG TGGGAYAARTGYTTYTTYGAYCCNCARAARMGNAARGCNTTYACNYTNTAYTAYGARGAR AAYYTNACNGARGCNYTNYTNGARGCNCAYGARAARGARYTNGARACNGTNMGNGAYTAY TTYAARCARCAYAARGAYATHTTYGARMGNYTNCAYCARMGNGARGARYTNTTYAARACN ATGYTNGTNTTYGARTCNAARGCNAAYGAYCCNAAYMGNTTYTTYAAYGAYMGNGGNGGN AARYTNYTNCARGARGARAARGCNMGNAARAARATHCARAARGAYYTNCCNAARYTNGAR GARGARGTNGCNGARTTYATHTCNCARTGYGARAAYAARAAYCARMGNGARTTYTAYGTN AAYGGNYTNMGNTTYCCNCARTAYGCNATHCARCARTGGGARGAYTTYCAYMGNCAYAAR GARYTNGARAARCARGARMGNATGAARGCNMGNGCNAARCARACNCARGTNGARATGYTN TAYGGNAGYAARTCNGTN------ACNCCNGGNAARMGNAARGTNGGNGCNCCNTCNACN CCNATGMGNACNCCNYTNAARGCNMGNAARYTNAAYGGNACNATHAARACNCCNAAYACN ACNAGYMGNYTNCCNNNNNNNAGYNNNNNNCANCANNNNACNYTNYTNCAYTCNTTYNNN NNNNNNNNNNNNNNNACNCCNGTNACNACNTCNAAYMGNAARMGNMGNTCNATHMGNYTN ATGAARAARTCNGCNACNGARMGNMGNAGYTCNAAYTCNAARMGNMGNMGNTCNMGNGAY YTNTTYTCNCAYACNGCNGTNAGYAGYGAYTCNACNCARAGYAAYTCNYTNGCNTCNACN GGNACNTAYMGNGAYTTYTCNAGYGGNYTNGTNMGNCCNAAYTGYMGNAGYAGYGTNGCN CCNGGNTCNGARAAYATGGARAARGCNGTNGAYACNYTNGARGGNATGTTYMGNAARACN GAYAARGAYYTNGAYTAYATGTCNMGNAARYTNGAYTGYCAYYTNGARAAYATGCARGGN GTNGAYCARAARGTNAAYCCNGTNAARYTNATGAARAARATGGARYTNATHAARACNGAR TAYGCNAAYATHGTNAARGAYGCNYTNGCNGTNCARGARGCNCARAARGARTTYTCNGAY TAYTTYMGNTCNCARYTNYTNACNYTNACNAGYGTNYTNGGNAARYTNGARATGACNACN GGNCARTCNTCNGARCARGAYGARATGACNACNGARGTNTTYGGNCARYTNTCNAAYYTN YTNGGNATH------------------CCNCCNGGNGARYTNGARTCNCAR------CAY GCNAGYGCNGCNTCNCARTCNGCNGGNGGNGAYGAYAAYTCNTCNACNTCNGCNCCNTCN GARTCNTCNAARTCNACNAARGCNAARCARAARACNAARTCNGARTCNGCNAGYGTNGTN GAYMGNMGNGCNAARAGYGAYGARTTYTGYGARYTNTCNGARCARGARTTYCARTCNGTN TCNAARTCNYTNACNCARMGNYTNAARYTNGAYGAYGTNAAYAARGTNTAYMGNMGNYTN TGGCARCAYTTYAARGARGARAARAAYACNGGNAARYTNACNCCNAARGARATGAAYGCN ATGGGNYTNMGNGTNACNGGNGCNACNGGNGARAAYAARYTNAARGTNYTNMGNTCNYTN AARYTNTGYGARATH---AARAAYGGNGAYGTN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TCNGGNAARYTNGGNCAYGCNTTY TAYAAYGTNTCNTGYGCNACNYTNGCNMGNAARYTNYTNGGNCARCAYGTNGTNMGNTCN ATHGGNGGNCARAARATHATHGGNMGNATHGTNGARACNGARGCNTAYATHGGNCCNATH GAYAARGCNGCNCAYAGYTAYCARGGNAARMGNACNCCNMGNAAYGARGCNATGTTYATG AGYCCNGGNACNTGYTAYGTNTAYAAYATHTAYGGNATGTAYTGYTGYATGAAYATHTCN AGYYTNGGNGAYGGNGCNGCNGTNYTNYTNMGNGCNYTNCARCCNATHGARGGNCARGCN CCNATGGARGARGGNMGNAARGGNAARGCNGGNGCN------GARAARAARCCNYTNAAR GARAARGAYYTNGCNAAYGGNCCNTCNAARYTNTGYCARGCNYTNCAYATHTCNAARAAY GAYTTYAAYCARATHGAYYTNACNTCNTCNGAYTCNYTNTGGYTNGARGCNGGNGAYTGY GTNGARGARGAYAGYGTNGTNAARTGYGCNMGNATHAAYATHGGNTAYGCNCARGAYTGG AARGAYACNCCNYTNMGNTTYTAYGTNYTNGGNAAYAARTGYGTNAGYGTNMGNGAYAAR AARGTNGAR------------------------ATGGTNTGYTAYTAYACNAAYTGGGCN CARTAYMGNCCNGGNTTYGCNAARTTYACNCCNGARGAYATHGAYCCNACNYTNTGYGAY CAYTAYCAYTAYGCNTTYGCNAARTTYAAYGCNAAYCAYACNATHGCNGCNTAYGARTGG AAYGAYGARAGYACNGAYTGGATGACNGGNATGTTYGTNAARTTYAAYAAYYTNAARAAR AARAAYCCNTCNATGAARACNATGYTNTCNYTNGGNGGNTGGAAYYTNGCNTCNGGNCCN TTYTCNAGYATGGTNTCNTCNACNGCNAAYMGNATGGCNTTYATHGAYAGYGTNATGCCN TTYYTNMGNAARTGGGGNTTYGAYGGNYTNGGNATHGAYTGGGARTAYCCNGGNTCNMGN GGNAGYCCNCCNGGNGAYAARCARATGTTYACNGTNYTNGTNAARGARYTNATGGCNGCN TTYCARGCNGARGCNAGYAGYACNGGNAARGCNMGNYTNATGYTNTCNGCNGCNGTNTCN GCNGGNAARTCNACNATHGAYAGYGCNTAYGARGTNGAYAARGTNGCNAGYGTNYTNGAY TAYYTNGTNGTNATGACNTAYGAYTTYTTYGGNGCNTGGGARCCNTAYACNGGNYTNGTN AGYCCNYTNTAYCCNCCNAARAAYGCNACN---GGNATHGAYGCNATHTTYAAYGTNAAR TAYGCNACNGAYTAYTGGGTNAARAARGGNTGYCCNAARAAYAARYTNGTNGTNGGNGTN ATHTCNTAYGGNMGNTCNTTYACNYTNACNAAYCCNTCNAAYTCNGGNYTNAARGCNCCN ACNAAYGGNGCNGGNACNCCNGGNCARTAYACNMGNGARGCNGGNTTYYTNTCNTAYTAY GARGTNTGYAARATGATHCAYCARGGNGCNAARATHGTNMGNYTNGARCARGARAARGTN CCNTAYYTNGTNYTNGGNAAYCARTGGGTNACNTAYGARGAYAARCARAGYYTNGCNATH AARGCNAAYTTYATHMGNGCNGGNGGNTTYGCNGGNGGNGCNATGTGGGCNATHCCNYTN GAYGAYTTYAARGGNACNGTNTGYGGNGARGGNGCNTAYCCNYTNATGTCNACNTTYTCN AARACNATG--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------CARCARYTNAAYATGAAYGGNAAYGARGAYGGNAAYTGYGCNTAYAAY TGGAGYACNAARAARTAYACNMGNTGYGTNAARGARGAYGTNYTNTGY------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARGGNAAYCAYAGYTAYGGNCCNTTY TTYYTNGARTAYTCNYTNYTNGCNGARTAYCAYCARYTNCARTCNCARAARYTNCCNGGN GTNTAYGTNATHCCNTCNGCNAARTCNACNYTNGTNTGGAAYGGNGTNYTNTTYATHMGN CARGGNYTNTAYCARGARGGNGTNTTYAARTTYAAYGTNATHATHCCNGARAAYTAYCCN GAYGGNGAYTGYCCNMGNYTNATHTTYGAYCCNCCNGTNTTYCAYCCNGTNGTNCAYCCN GAYACNGGNGARYTNGAYTGYAARMGNGCNTTYCARAARTGGMGNMGNAAYGTNAAYCAY YTNTGGCARGTNYTNYTNTAYGCNMGNMGNGTNTTYTAYAARATHGAYACNAARACNCCN YTNAAYCCNGARGCNGCNGTNYTNTAYGARMGNGAYYTNGARYTNTAYAARCARAARGTN TAYGARTCNATHCARATHTCNAARGARAARYTNTAYGAYCCNCCNAAYAAYGAYGAYCCN CAYGCNATHMGNTTYAGYCARYTNGAYCCNGCNGTNCAYGAYGARGCNAARYTNCARYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GAYGARTGYMGNCARTGGTAYATGTGY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGYTNGGNTCNGCNCCNGARTCNAGYGCNAARGTNTAYGCNMGNGARCCN TTYATHAGYCARGARGGNTTYGTNTTYYTNTCNGCNGAYTTYCARCARATHGARTTYMGN ATHYTNGCNCAYYTNTCNGARGAYAARGCNYTNYTNTCNATGTTYTGGAARCCNGAYAGY YTNGAYATHGCNGARTAYYTNAARGTNAARCCNGAYGTNGCNAARCARGTNATGCARAAY TTYYTNGTNMGNTTYCCNGCNATHGAYTCNTTYACNAARAARTGYTGYTCNTAYGCNAAR GARTAYGGNTAYACNGARACNATHTGYGGNMGNMGNMGNTAYTTYCCNTTYATHAAYAGY TCNACNCCNGGNYTNMGNGCNCARGCNCAYMGNCARGCNGTNAAYTTYTGYATHCARGGN TCNGCNGCNGAYATHTGYAARYTNGCNATGYTNGGNGTNGARTCNAGYYTNMGNAARCAY CCNGARATHAAYTGYMGNYTNYTNATHCARATHCAYGAYGARYTNYTNTGGGARGTNGCN GARGAYCARYTNTCNCARGCNAARGARATHATHGARAGYGTNATGGARAAYACNAARATH YTNTGYAGYAAYTTYTGYTCNYTNCARATHCCNYTNGCNGTNTCNTTYAGYCARGGNAAR TCNTGGGCNCAYYTNACNCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GARGARTAYTAYAAYAAY TTYATHATHAAYGGNTAYGAYATGGGNACNATHTCNMGNATGACNCCNGARGAYYTNACN GCNATHGGNGTNACNAARCCNGGNCAYMGNAARMGNYTNAARGCNGARATHACNMGNYTN CAYATHCCNGAYGGNYTNCCNGAYTAYAARCCNAGYAAYYTNTTYGARTGGYTNCARGCN YTNAAYYTNGTNGARTAYCAYGAYACNYTNAGYMGNCARGGNTAYGARAAYYTNGAYYTN ATHACNGAYATHACNTGGGARGAYYTNGARGARATHGGNATHAARAARYTNGGNCAYCAR AARAARTTYGTNYTNGCNATHGAYMGNYTNAARMGNATHGAYAGYGGNGCNAARMGNCAR TCNTCNATGGAYMGNMGNGGNTCNAGYGARATHYTNGAYGGNCCNCAYGTNGTNCAYCAY CAYGTNAGYMGNTGGGCNAAYGARYTNGGNAAYCAYCCNATGGTNGARGCNGAYGTNTCN AARGAYGTNGTNGAYCCNGAYATGMGNTCNGCNYTNCARAGYATHATGGARGARYTNATH GAYGARGTNTCNYTNGGNYTNTGYTTYGARATHCAYMGNTCNTGYAARATHGGNTCNTTY TTYYTNGAYGGNTGYGAYGAYACNTCNGAYACNGAYTAYGCNATHATHGARMGNCAYGGN GTNGAYGTNYTNGGNCARGTNTCNTCNAARAARAAYTAYGARTGYGCNTGYCCNAAYTGY CAYMGNCAYYTNGCNGCNTCNMGNTTYGCNCCNCAYYTNGARAARTGYATGGGNATGGGN MGNAAYTCNTCNMGNATHGCNAGYMGNMGNATHGCNAAYAAYCARAARCAYGGNAGYGAY GARAGYGGNCARGAYGAYGARAAYGAYAAYGAYTGGAAYTAYGCNCCNGARTCNAARMGN YTNMGNAARYTNAARAARGAYAARATGTCNAAYTCNCCNMGNAAYMGNMGNYTNGCNAAR YTNMGNAAYAAYAAYYTNCAYAARYTNMGNAAYGGNGCNGCNAGYGCNACNGCNACNGTN GCNGCNGCNGCNGCNTCN---------ACNATHTCNACNGCNACNACNACNYTNTCNGCN CCNGGNACNGTNGCNACNAGYGAYGTNACNGAYAGYCAYGAYGCNGTNCCNAAYTAYGAR ACNATGTCNYTNGARGAYMGNAARGCNYTNYTNYTNACNMGNTGYGGNGTNATHTCNGAR CAYACNAARAARATGTGYACNMGNTCNACNAARTGYGCNCARCAYACNGARGARCARMGN MGNCARATHMGNCARTTYYTNYTNMGNCARAAYMGNAGYCAYGARYTNGARGAYATHCAY ATHGAYATHGAYACNTAYGAYGAYGCNGARTCNCARTCNYTNMGNGARTCNYTNCARTGG GARGCNTCNTCNAAYTCNTCNCCNGCNGAYTCNACNTCNACNAAYAAYAGYACNAGYGGN ACNATG------------------------AARMGNTCNAGYAAYAARTCNGGNAARTCN AGYAARAGYAARAARTCNAARACNATHAARACNAGYGTNTCNAGYTCNAGYAGYGCNGGN AGYGCNAARGAYATGGCNACNGTNAGYYTNTTYGAYTTYGARTTYATHTGYMGNTGYTTY TAYTCNMGNAAYATHTTYYTNAGYAARTAYCARYTNCAYGTNAGYTAYAGYAAYGAYGAY CARTTYTAYCARGAYTGGMGNCARGAYYTNMGNATGAARGGNTGYGCNACNGGNAARCAR TAYGARGCNGTNYTNGAYGARATHAARAARGARGTNTCNMGNMGNAGYAAYTTYCAYCCN GARGCNYTNAARMGNCAYCARACNATHTGYGARAGYTAYGAYMGNYTNCAYCCNCAYYTN TGGGAYTTYAARGCNTCNTAYYTNGAYGARMGNYTNGCNYTNATHGTNAAYTCNGTNCAY CARGAYYTNACNAARGARGAYGCNGARAAYATHATHGTNCARAAYGGNGGNAAYATHATH GGNAAYAAYYTNTAYMGNYTNCCNATHTTYTCNACNGGNTTYTGYGARCAYYTNGTNGAR GARYTNTCNCAYTTYGARGARAGYGTNTGYCCNAARGGNMGNCCNAAYACNATGTCNAAR TAYGGNATHTCNYTNGAYGARYTNGGNATGTCNGARGGNYTNYTNATHCCNYTNATHACN GARTTYATHCARCCNYTNTCNACNATHYTNTTYMGNGAYMGNTGYGGNGARMGNYTNGAY TCNTTYMGNGCNTTYTCNGTNYTNTAYGGNCCNGGNAARGAYACNGARYTNAGYATGCAY TTYGAYAAYGCNGARGTNACNYTNAAYGTNTGYYTNACNTCNCARTTYGARGGNGGNGAR YTNGARTTYGGNGGNYTNCARGAYGAYGCNCARACNTCNACNCAYMGNGAR--------- ---ACNGTNATGCAYACNATGGGNACNGGNGTNYTNCAYYTNGGNCARCAYCAYCAYMGN GCNYTNCCNATHGCNTTYGGNACNMGNTGYAAYYTNATHYTNTGGATGMGNAGYTCNGCN GTNMGNAAYAAYTTYTGYMGNATGTGYGGNTGYCARCCNGAYYTNGTNGARGTNCCNTTY GCNGGNGAYGGNTTYACNMGNCARGGNAGYAGYCAYTAYTCNGCNAAYACNTGGMGNAAY GCNGCNATGATGGGNTAYATHTAYGGNGGNGTNMGNTAYACNAAYMGNTAYCCNACNMGN MGNCARATGCCNCCNATHTGYACNAAYAARTAYGCNMGNGCNCCNGARGGNCARGTNTAY GGNCCNTTYATHTGYCCNMGNATGAAYGARACNATHGCNGAYATHTAYTGYTGYGGNCCN AARTAYMGNGARTTYTGYTGYAAYGTNACNGARGCNAARYTNTAYTAYAGYATGCAYCAY ACNAARAARAGYAGYGGNGGNYTNGGNGCNATHATHGGNATHYTNATHGCNATHTGYYTN GGNGTNGCNGTNGGNGTNTAYTGYTGYAARMGNMGNMGNCARGARGGNGTNGTNATHGAR ACNAARACNGTNGARGTNACNACNACNTCNAAYCARATGGCNCCNCCNCCNTAYAAYGAY CCNTAYCARYTNCCNCAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNGCNYTNGCNGAYYTN TCNTGGTCNTTYATHACNGGNATGGCNGAYGARAAYTTYACNYTNGCNGGNACNCAYGGN TAYGAYAAYGARTAYAARGAYATGMGNCCNTTYTTYATGGCNACNGGNCCNTCNTTYAAR TCNGGNTAYGARATGGAYACNTTYAAYAGYATHGAYATHTAYGCNYTNATGTGYCARYTN YTNCAYYTNAARCCNAAYCCNAAYAAYGGNACNYTNACNAARGTNTCNCARYTNYTNCAY GGNCAYGARAAYACNGTNGTNACNTTYTCNACNTAYATHATHGTNYTNATHGTNATHGCN AGYGTNGGNGGNGTNTTYATHGTNGCNGCNTGYMGNCARCAYMGNTAYYTNAARMGNAAR YTNAAYCARYTNAARAAYTCNGGNGAYTTYMGNAAYTTYGARATHACNACNCARTGGGAY GGNGARTGYGTNAGYAAYAAYCCNGTNAARATHTCNYTNGGNGARTGYCCNAAYGGNAAY YTNYTNATHAARGTNGAYGCNCCNTTYTTYGAYATHTCNCCNAARCCNGAYGGNCCNGTN GGNGARMGNTTYTTYAARYTNTGGGAYTAYGARGTNGTNGARGCNTTYTTYYTNAAYGAY GAYAAYCARTAYYTNGARGTNGARYTNGGNGCNCAYGGNCAYTAYYTNACNYTNYTNYTN AAYGCNACNGGNAARGCNGCNCARCAYAARYTNCCNATHAARTAYAARATHGARCARAAR GGNGAYCARTGGACNGGNGARGCNTTYATHCCNMGNAGYTAYYTNCCNCCNGGNGTNACN AARTTYAAYGCNTTYGCNATHCAYGGNCARGGNGARACNMGNGARTAYCARGCNYTNTAY CCNGTN---------CAR---------GARAARACNACNGCNAAYTTYCAYMGNYTNGAR YTNTTYAARACNATHGAYATGAARTCNTTYYTNCCNAGYTAYGAYCCNACNTCNATHTCN AGYGTNTGGGCNCCNCAY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ACNCARGARGCNGTNTTYTCNATHGTNGGNAARAARATHATHGARAGYTGY GTNGCNGGNTAYAAYGGNACNATHTTYGCNTAYGGNCARACNGGNTCNGGNAARACNTTY ACNATGYTNGGNCCNTCNGARAAYGCNGAYAGYTTYCARCAYGARYTNMGNGGNGTNATH CCNMGNAGYTTYGARTAYYTNTTYAGYYTNATHGCNCAYCARCAYGARYTNCAYGGNAGY AARMGNCARTTYYTNTGYMGNTGYTCNTTYYTNGARATHTAYCARGARCARGTNTTYGAY YTNYTNGAYCCNACNTCNCARGGNYTNCAYYTNMGNGARAAYATGAAYAARGGNGTNTTY GTNGAYGGNYTNATHGARCARGTNATHTGYAGYCCNAGYGAYGCNTAYCARGTNYTNATH ATGGGNTGGYTNAAYMGNMGNGTNGCNGCNACNTCNATGAAYMGNGARAGYTCNMGNTCN CAYGCNGTNTTYACNGTNACNATHGARTCNAARGARGAYGTNGAYGGNGTNCARAAYATH MGNACNTCNCARYTNAAYYTNGTNGAYYTNGCNGGNTCNGARMGNCARAARGAYACNAAY ACNGGNGGNACNMGNYTNAARGARGCNGGNAGYATHAAYAARTCNYTNTCNATGAAYAGY GAYTCNGTNTGGYTNMGNAAYTTYYTNGARGCNATGCAYTAYMGNGARGTNTCNGARAAY GARAARAARGCNYTNCARGAYGTNGTNAAYCAYYTNCARGARYTNTGYAAYAARAARGAY TCNTAYATHCARTCNGCNAARATGATHATHAARTTYMGNGARGARACNATHTCNACNYTN MGNCARAAYCCNAGYYTNCAYYTNGARYTNGAYAARGAYCCNATHGTNAARTCNYTNCAY GAYGARATHAARGTNYTNAAYCARCARGTNGAYTCNAAYCCNCARYTNGCNAARTAYGCN GGNGARAAYMGNCAYYTNMGNAGYGARYTNAARMGNYTNAARGCNCAYAAYTCNGTNGAR GARGTNYTNAGYGAYACNGTNCAYATHGCNMGNYTNGARAARATHTTYMGNGARGTNCCN AARTTYYTNGGNTCNATGACNYTNAARGCNYTNYTNGARGAYCCNAAYYTNAARAAYCCN CCNATHATHGGNCARTCNGGNAARCARGTN---------AARAARGARGARGGNTCNGAY YTNCCNCARTAYAAYTAYGGNTCNGCNTTYYTNGGNTCNACNYTNTGGGAYAARTCN--- GGNATHGAYYTNAAYYTNGARTAYATGGAYYTNGAYGARTTYYTNTCNGARAAYACNATG GARAAYACNATHGCNGAR------GAYGAYTCNYTNCCNGTNAAYCCN---------GCN CCNAAYCARATHGTN---------------------------------AGYTCNCCNMGN GARTTYYTNMGNACNCCNCCNYTNAGYCCNTCNCAYTAYYTNATGMGNGGNCCNACNGTN ACNCCNCCNCAR---CCNTCNCARCCNTTYCCNACNCARCCNTCNTCNCCNTCNTCNTCN CCNGGNAGYCCNTCN---TTYAAYGTNGAYTTYCARGTNTCNGARCARGAYYTNGCNYTN ACNGTNGCNCCN------------------------------------------------ ------------------------------GGNCAY---AAYTTYGAYCCNMGNAARMGN AAYTTYACNGAYGARGARYTNAARCCNCARCCNATHATHAARAARTCNAARAARATHTTY GTNCCNGARGAYYTNAARGAYGAYAARTAYTGGTGYMGNMGNATHAARAAYAAYTAYGCN GCNAARMGNTCNMGNGAYGCNMGNMGNGTNAARGARAAYCARATHGCNYTNMGNGCNGCN TAYYTNGARAARGARAAYAARTGYYTNAARGAYGARATGTCNAARYTNMGNAARGAYAAY GCNAARYTNAARACNATHGTNGAYAARTAYGARCCNGGNGCNACNGAYGAY--------- AAYMGNCARGCNTAYATGGAYGCNGTNYTNCARGAYCAYCARCARACNATGTCNGTNATH CCNYTNACNMGNCARGCNAGYTCNCAR---TCNYTNGARAAYATHGAYTCNMGNTTYATH AARCAYAAYAARGTNATHCARMGNATGGGNGCNTCNAAYCARAARGGNAGYMGNGCNCAR TCNGCNAARGTNMGNTCNMGNCCNACNGCNAARGAYCARGTNAARGCNATGGAYATHTCN YTNAARGAYYTNATGGGNGARACNCCNTCNAGYAAYCAYTTYGTNGAYTCNGAYGCNMGN GGNGARCCNMGNATHATHACNCCNTTYCARAAYAGYAARMGNMGNCCNCARACNTGYCAY GTN------MGNCARCCNAAYACNTAYAAYGAYCCNAGYMGNTAYAAYAARGGNGAYGTN TAYGARYTNMGNGAYGGNGAYGGNGTNAARAARCCNMGNCCNGTNAGYGCNTCNAGYYTN MGNGARGGNGAYGCNTTYMGNTCNMGNCCNCAYACNGGN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GCN CARGARGGNTCNCARCAYTAYMGNGCNGCNATGGCNGCNCAYTAYACNATGAARTTYTGG CARYTNATHCARMGNGARCARTAYAARCCNATGAARGAYAAYAARGGNMGNCCNYTNTGY ATGTAYCARTTYMGNMGNYTNTTYAAYGCNTGYMGNATHCCNGGNGTNCAYMGNGAYAAR YTNGARGARTAYTTYGCNACNGARGCNGARGGNGARTGYCCNTCNCAYYTNATHATHATG TGYAARGGNCAYATGTTYTTYYTNAAYGCNYTNGAYGAYGCNGGNGARGTNYTNACNCCN YTNGARTTYGARAARCARTTYAAYTAYATHMGNCARGARGCNGARAAYYTNGGNCCNTCN CARGAYGTNAAYTAYYTNACNTCNYTNCCNMGNACNACNTGGGCNGARTAYMGNAAYYTN YTNGTNGCNAGYCAYCCNCAYAAYACNGARGTNYTNCARAARATHCARAGYGCNATHACN GTNTAY---------------------GGNYTNATGAAYGAYYTNACNAAYAARAGYYTN YTNGGNAGYATHCARAAYMGNTGGTGYGAYAARTCNATHTCNAAYATHGTNTCNAARAAY GGNYTNYTNYTNTGYAAYGCNGAYCAYTCNTTYTGYGARGGNATHATGATGGTNTTYTTY ACNAGYTTYGTNCAYCARAARYTNMGNGARTGYAAYGGNGTNTGGCARGGNACNAARGCN ACNMGNCCNCARCCNCARCCNCARYTNYTNAARTTYGTNGTNCCNGAYCARYTNACNCCN GGNATHGARATGGCNAARAARATGTAYAARGARTTYCARAGYTGYGGNTAYTGYGTNATG YTNAARTAYGARGGNTAYGGNAARGCNTAYYTNAARAARGTNAARATGCAYCCNGAYGCN CAYTGYCARYTNGCNATHCAYYTNGCNTAYTAYACNATGTAYGGNMGNATGGCNCCNGCN TAYGARACNGCNCCNATHAARCARTTYTAYCAYGGNMGNACNGARACNYTNMGNTCNTGY ACNAAYGARGCNGTNGARTGGTGYAARAGYATGTCNGAYCCNTCNTGYTCNAAYGARAAR MGNTGYAARYTNTAYGCNAARGCNGTNAARAARCAYAGYACNACNATGGCNGAYGCNTGY GARYTNAARGCNTGYGAYMGNCAYYTNATGGGNYTNAGYYTNATHGCNAARGARCAYAAY ATHCCNYTNCCNACNYTNTTYCARGAYCCNGCNTTYGTNAARAGYGGNGGNGGNGGNAAY TTYYTNYTNTCNACNAGYAGYGTNGGNTAYACNTCNGTNATGGGNGGNGTNYTNCCNATG TGYGARAAYTGYTAYGGNTGYTTYTAYACNATHAAYGAYGAYAARATHAARTTYTTYATH ACNACNTGGACNGCNGAYAARGAYACNAGYAGYCARGGNTTYGCNGAYACNYTNACNAAY AGYYTNGAYAARATGAARAAYATGATHGAYCARGCNTTYMGNGCNAGY---GCNMGNYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATHACNATGACNTGYACNGCNACNGGNCCNACNGAYTAY GGNATHTAYTGGAARMGNMGNTGYCCNTCNCCNTCNTCNGTNACNCCNAGYTTYACNGCN TGGCCNATHGCNAAYGARATGACNGAYAARAARAARGAYATHGGNAARGARAGYTCNTGY GGNGARTTYAARCAYAGYCARAARYTNACNTTY------AARATGACNTCNGARGTNTGY GCNGTNMGNTGYGARTTYGGNGAYAGYATGTGGTCNAGY------GAYAAYTCNATHGCN AAYTTYACNGTNAAYYTNGAYGCNGCNGTNGTNCCNGAYGGNAAYACNGGNAAYCCNTCN AGYGCNAGYAAYAGY---GGNYTNGTNATHGGNYTNGTNGTNGGNYTNYTNYTNATHYTN ATHATHGTNGCNGCNGTNYTNATHTAYTTYTGYTGGTGGMGNAARMGNAARCARGCNCAR GARAARTAYACNGCNGARGCNGARGAYCCNAAY------------------CAYGCNCCN CCNCCNGTNTTYTAYTCNAARCCNCAYAARCCNCCNAARGAYGAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AARCAYATHYTNATHYTNCARACNGGNGGNACNATHGAYAARMGNTAYCCN CARGGNCCNGGNGCNTAYGCNTTYGARTTYGGNGARTCNGCNGTNGARAARATHYTNMGN CAYATHTGYCCNACNTTYCARTAYTCNATGMGNCARATHTGYGCNAARGAYAGYCARGAY ATHACNGAYACNGAYMGNGTNGAYATGYTNCAYGTNATHATGGARTCNGARCAYTCNYTN GTNYTNATHACNCAYGGNACNGAYACNYTNTGYGARACNGCNMGNTAYYTNGTNACNGCN GGNGTNGGNAAYGGNTCNACNTCNCARGCNGGNATHGGNGGNAARACNGTNGTNYTNACN GGNGCNTTYYTNCCNGARACNATGAARGAYTCNGAYGCNGAYTTYAAYGCNGGNTTYGCN YTNGGNTTYATGCAYTCNTCNCCNGCN---GGNGTNTTYGTNGCNATGGCNGGNGGNATH YTNGAYGGNGCNCAYGTNATGMGNYTNGARGAYGGNAARTTYGTNGAYMGNMGNCARYTN YTN---------GAYACNATHGARGAYTTYGTNTAYGTNAARYTNCAYTGYCCNTTYAAR MGNATHTGYGTNGARGCNGARMGNGTNAAYATHGARATGCCNYTNMGNGAYTGYGARGTN CCNGARACNAARATHMGNAAYCCNATHYTNMGNTAYGTNAAYAARCAYTTYGAYGCNGAR AGYGAYGTNAGYGAYTTYGTNAGYGCNCARTTYYTNATGGAYAARATHCAYYTNTTYGAR GGNTAYGARGAYCCNACNAAYTTYTTYMGNCCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------TTYAARAARGAYTCNMGNGTNTGG YTNCAYAARAAYTCNAARMGN------------------------------------YTN GGNAAYGAYATHGTNMGNTTYTCNCCNGGNCARGARGARGAYYTN---GAYACNGTNCCN CCNATHACNGGNGCNGAYGGNMGNGTNTAYAARAARGAYAGYMGNACNTGGYTNCAYAAR TCNTCN------ATGYTNTCNMGNTCNGGNMGNGCNGARACNMGNAGYMGNGCNAARGAR GAYATHAARMGNGTNATHAAYGCNATHGAYAARGTNMGNAARTGGGARAARAARTGGGTN ACNYTNGGNGAYACNTCNGTNACNATHYTNAARTGGGTNCCNTGYACNGCNCARGARAAY CCNGGNGCNYTNMGNAARATHCCNGGNGTNAARACNAARACNTAYTCNAARGCNMGNGTN GAYMGNGARMGNGARYTNTAYGCNGCNGARACNAAYGGNYTNCCNMGNGCNAAYTCNCCN GCNGAYTCN---AGYAAYAAYACNAAYGTNTCNAAYACNAGYTCNCCNTCNTCNMGNAAY ATHAAYGGNAAYGGNGARAARGCNAARAAYGGNAAYGGNTCNAAYACNAGYGGNAAYGTN GTNTAYTCNGARGARAAYACNCARCARTCNATHGGNTCNTAYGGNTCNGARAAYYTNAAY GARGAYTCNAAYATGTCNTTYCCNGARAAYAGYGARYTNAGYGARCARGCNGAYCAYAAY GARTTYTCNCAYGAYAGYAAYGAYGCNGAYCCNGGNATGMGNGTNGCNATGAGYATGGTN GGNGAYGARGAR------------------------------------------------ ------------------------------------------------------------ ATGTCNGARGTNCAYGAYTTYGGNGTNGCNCCNATHACNTGYCAYTCNTTYAAYAARGAY MGNAAYGGNYTNGCNATGTCNYTNAAYGAYGARGAYGTNAARATHTTYAARAARAAYGGN GCNAARTGGGAYGARACNGAYACNYTNAGYGARCAYGGNCARMGNGTNACNAGYATHGAY TGGGCNCCNAAYAGYAAYMGNATHGTNACNTGYTCNGCNGAYMGNAAYGCNTTYGTNTGG ATGYTNGARGAYGGNAARTGGAARCARGTNYTNGTNATHCCNMGNATHAAYMGNGCNGCN ACNTGYGTNAARTGGTCNCCNCARGARAAYAARTTYGCNGTNGGNAGYGGNTCNMGNYTN ATHGCNATHTGYTAYTAYGAYGAYGARAAYAAYTGGTGGGTNAGYMGNCAYATHAARAAR CCNATHMGNTCNACNGTNACNTGYYTNGAYTGGCAYCCNAAYAAYGTNYTNYTNGCNGCN GGNTCNACNGAYTTYAARTGYMGNGTNTTYTCNGCNTAYCARAARGARGTNGAYGARMGN CCNGGNGCNTGYTCNTGGGGNACNAARATGCCNTTYGGNGCNYTNATGGCNGARTTYAGY AAYGGNGGNGGNGGNTGGGTNCAYTCNGTNTCNTTYTCNCCNAGYGGNAGYYTNGTNGCN TGGGTNGGNCAYGAYTCNAGYGTNTCNYTNGCNGAYTCNAAYAAYGGNAAYGARYTNTTY ATHATHAARGAYAGYTTYYTNCCNTTYATGAGYATHACNTTYGTNACNGARAAYTCNATG GTNGCNGCNGGNTAYGAYTGYAAYCCNATGYTNYTNTCNTAYGCNGGNGGNAARYTNACN AAYCARGGNAARYTNGAYGTNCCNCARCARAARGARTCNGGNACNATGAGYGCNATGAAY MGNTTYAARAAYYTNGAYAARAARGCNAGYGCNGAYAGYGAYACNACNCARATGAARACN YTNCAYCARAAYACNATHACNCARGTNTCNATHCAYACNGGNACNAARCARGAYGCNYTN AARYTNGCNACNAGYGGNGTNGAYGGNAARYTNATHYTNTGGGAYYTNAARYTNGARAAY GCNACNCAYAARCCNTCNGGNGGNGARAARAARATHMGNGAYGARAARYTNACNTGGAAR GCNGARTCNAARGTNGGNTCNYTNAAYAAYGCNACNCAYAARCCNGGNGGNGGNGARAAR AARGARGARAGYGARAARTGYGAYTGGGARGCNAARTCNAARATHMGNTCNTTYTCNAAY GTNAARCAYAARCCNTGYGGNGGNAAYGTNAARATHACNGAYGARAARGTNGCNTGGGAY GGNAARTCNAARATHMGNTCNYTNGCNAAYGTNAARCAYACNCCNAARGGNGGNGAYATH GARATHYTNGAYCARAARATHTCNTGGGARGCNAARTCNAARGTNCARTCNYTNGAYAAY GCNAARCAYMGNCCN---------------ACNTGYGAYYTNTGYCCNYTNCCNCARYTN ACNGCNTAYTGGACNGCNCCNCCNTCNTGYCCNMGNMGNATHTGYTGYGARAGYAARTCN CCNTGYTGYTCNTCNGGNTGYTTYMGNGARGGNAARTAYGTNACNGTNTTYTTYTTYGCN ACNATHGGNACNTAYTTYYTNATHATGGAYATHYTNYTNTAYTGYTAYTAYATGAARACN AAYYTNGTNGARAGYTCNACNGGNGGNGGNATHGAYGARATHTAYACNCCNTTYACNCAY YTNTCNGTNAARGCNYTNYTNAAYGAYCARCCNAGYCARTAYYTNATHGCNCCNAGYACN GARTGGYTNGARTAYTAYACNGGNTTYGCNAARACNTTYTAYTTYATHACNCCNAAYGTN GTNTCNTTYTGYCAYYTNATHGTNGGNTTYGTNTCNGGNAARTTYGTNTCNTCNGAYAAY YTNTCNGAYMGNMGNATHGGNGTNGTNYTNTTYGARATHMGNACNTGGYTNGAYGCNTTY GAYGGNACNGTNTTYMGNGCNCARCCNGGNCAYCAYYTNCARTAYAGYTCNATHCAYAAY ACNYTNGGNTAYTAYATHGAYTCNGTNTTYGAYACNYTNGGNGGNTGYTTYYTNTGYTTY GGNGTNTAYTTYTAYTTYYTNAARMGNTGYGGNCCNCCNMGNATHCARTGYGTNYTNCCN TTYTGGTCNTCNGCNCCNGAYTCNCARAAYAARGTNCCNYTNGTNAGYGAR--------- AGYGGNACNGCNGARACNTAYAGYGCNTAYTAYYTNTTYTGGAARAGYTTYTCNTTYGGN YTNGTNYTNYTNGTNTCNGCNTAYACNTGGGAYACNGTNGTNGTNCARTTYACNGARGTN TTYCARACNCARYTNAARGAYCCNGARYTNTCNGCNYTNCARYTNAARYTNTCNCAYTCN GGNACNACNGTNTTYYTNTTYCARYTNTGGMGNYTNATHGGNTCNCARTGYATGYTNAAY TAYYTNYTNATHGTNATHTTYYTNGAYAARYTNTGGGARTTYTTYAAYGGNACNCARTAY YTNYTNATHATHTCNATHGGNAGYYTNTAYATHGCNTCNGTNGTNTAYATHAAYCARATH AARCARCARYTNCARATGCCNAARYTNATHGTNTTYGAYYTNGAYTAYACNYTNTGGCCN TTYTGGGTNGAYACNCAYGTNGAYCCNCCNTTYAAYGTNAARCCNAAYGGNAARGTNTAY GAYMGNMGNGGNAARCAYATHGARTAYTTYCCNGAYGTNCCNGAYATHYTNGCNAARYTN MGNTCNCARGAYTAYAARYTNGCNATHGCNTCNMGNACNAGYGCNCARCARGARGCNGAR GARYTNGTNMGNYTNTTYAARTGGGAYGAYTTYTTYGAYTAYMGNCARATHTAYCCNGGN TGYAARATHACNCAYTTYAARAARATHCARGGNGCNAGYGGNATHCCNTTYCARGAYATG YTNTTYTTYGAYGAYGARCAYMGNAAYATHGTNGAYGTNTCNACNYTNGGNGTNACNTGY ATGTTYGTNCCNGAYAAYGGNGTNTCNCAYGARTCNYTNAARGARGGNTTYGAYYTNTTY MGNGARAARAAYTCNAARMGNGGNCCNCCNAGY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARGAYCAYGCNGCNGCNGAYYTNGCNYTNGCNGARATGTCNGARATHYTNCAYCCNTCN GTNMGNGAYYTNAAYTCNTCNACNGAYGTNGAYMGNATGGTNTCNACNTTYCARGAYAAR MGNMGNCARYTNGARTCNMGNTAYCARCARYTNAAYAAYCARGGNYTNGCNGARAARGTN TTYMGNATHYTNACNAAYCARGAYCCNGARYTNCARGCNAAYGGNATHYTNTCNGARGTN AGYGCNGAYGARAARGARATGMGNACNMGNYTNGCNYTNAGYATGCARGAYAARAAYTTY AAYTAYTCNTCNACNTCNAGYTGGYTNGAYGARATGAAYCARAGYTTYAAYCCNCARGGN GARGTNMGNAARAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TGGYTNCAYTGYAAYGGNTGYTAYTGYCARCCNGARCCNGGNGTNGTNMGNTTYTAYATH ACNAAYTGYAGYCAYATHTAYTGYGARAARTGYGTNAGYACNTGYACNAARGARTGYTGY MGNGTNTGYCARTCNCARTGYACNACNYTNGARYTNAGYGGNAARATHCARAARGARGTN GARAAYYTNTTYGARGARCCNGGNACNATHATGCARAARGCNATGAARCARGTNAAYCAR GTNATHGARTTYCARMGNAGYCAYCARMGNMGNTGGTGYMGNCAYYTNAARGARATGGCN MGNCARCARGGNCARCARYTNMGNGAYGTNAARAARYTNGTNGCNCARTAYMGNACNCAR GARAARGARATHATGGAYYTNAARAARGARAAYAGYTAYYTNAARTGYYTNYTNGCNAAR AGYAAYMGNTCNGGNGCNTCNCCNAAYCARMGNAAYCCNCARTCNGTNAAYACNAAYGTN YTNTAYCARCCNGGNMGNATHYTNATGCCNTCNGGNGGNMGNYTNACNATGAARGTNTTY AARTGYGTNATGTCNTCNGAYGARATGTTYTCNGAYAGYTGYCCNTAYAARATHGARGGN GGNTTYTAYGTNGTNAARGGNAARTAYGTNTCN---MGNGTNCARGGNGARGTNGAYGAY AGYATGTTYGGNGGNAAYCCNAGYGCNGARGGNGGNGAYGAYGGNGGNAGYGARGTNGAR MGNGARTCNGGNATHGAYGTNATHYTNGAYCAYMGNYTNAARGARACNGTNTTYGGNACN AARAARGARTAYACNGCNTAYATGAARGAYTAYGTNAARGCNATHTTYAARACNYTNGAR AGYTCNAARTCNGCNGARGARATHGCNACNYTNAARGCNGAYACNACNGCNTCNTAYAAR GCNGTNYTNGCNAAYTTYAARGARTAYCARTTYTTYACNGGNGARAGYYTNAAYCCNGAY GGNCAYATHGCNATGYTNGAYTGGAARGAYGARGARGTNGAYGGNAARACNGTNAAYTCN CCNTTYGTNTAYTTYTAYGTNGCNGGNYTNYTNGARGARAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TCNGAYCCNGCNGGNATGTTYTGYGGNTCNGTN TGYTGGGARGARAAYGCNYTNGCNGARCARTGYGARMGNGCNAARGGNTGYGAYATHAGY ------MGNCARTCNTAYTCNAARTAYMGNMGNTGYAGYGARCCNTGYCARCARGCNGTN GCNGCNTGYCARMGNATGTGYMGNACNAAYTTYMGNACNGTNYTNGAYCARTGYACNCCN YTNTGYGARGGNGAYGGNTCNGARCAYTGYACNMGNGCNTGYTTYACNCAYMGNGCNYTN GGNYTNAARTCNCCNAGYCAYATGMGNGAYTAYGAYGGNTCNGAYAGYTCNGAYYTNGAY GARAARGAYCCNGAYGGNAAYGTNTCNGAYGARGAYACNGCNGAYGCNAGYGARACNGAR GARAARACNCCNAARGTNCARAARAGYGTNATHCCNAAYAGYGGNAGYCARMGNACNGAR ATHAARGARCARATGTAYCARGAYAARYTNGCNCARATHAARAARCAYATHGTNATGYTN CARGARGGNACNYTNCARGARTTYYTNAARMGNACNAARAARATHGARYTNAAYTAYMGN GARMGNYTNMGNCARAAYGARATHAGYAARAARGTNGAYATHGARAARTCNGARMGNAAY TAYCAYATHGAYTGYGARAAYACNCARAARGARTTYGARGARAARMGNGCNGCNYTNAAR GARTCNYTNATHAAYCAYYTNAARGARAARAARATHGAYYTNAARGARACNYTNATHACN GAYYTNAARGARAARMGNGGNATGATHGARYTNGARMGNCARACNGTNGAYYTNAAYGGN GCNGAYTTYATGGARGTNAARCCNACNGTNACNMGNAARYTNMGNMGNMGNCCNAAYGAY CCNATHCCNATHCCNGARAARMGNMGNAARCCNTCNCCNGCNCARGTNAAYATHYTNYTN GAYGAYGAYYTNATHYTNGCNGAYYTNMGNYTNATHATGAARGTNAGYGGNAARCCNYTN GCNAARAARCAYGGNTCNGGNACNCAYAGYCCNATHGTNGAYTCNTCNTCNGAYGTNMGN ATHGARGAYGGNMGNYTNTGGTTYGAYAARAARTGGTTYCARMGNAAYACNATGGTNCAR ATHGAYAAYAARGARGGNGGNTCNMGNATHTGYGGNACNATHACNAAYATHGGNAAYCAR GARATHTGGGTNAARAARAGYGGNGAYAAYTCNAARYTNMGNATHTAYGTNTCNCARTTY CARAARGGNAARTAYTCNATGAARAARMGNACNACNACNYTNGGNMGNACNGAYTAYCCN TCNGGNATGAARCARATHGTNYTNAGYTTYTTYACNAARYTNYTNTCNMGNYTNTCNCAY CCNYTNYTNCCNCAYGTNAAYGTNCAYMGNGCNGTNCARMGNATGGTNAARTTYTGYGGN GARACNMGNGCN------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTCNMGNCARCARGCNTCNAARGCN MGNGGNGCNGAYAARACNAARCCNCCNGCNTCNCARACNCCNGTNATHGCNCAYGARATH GTNCCNGGNAARTTYAAYGAYAAYGAYTGGAAYTGYATGYTNGAYMGNGAYGGNGGNGAY GARTTYGTNATGGAYATHATGGAYGARYTNATGGARAARACNATGAGYACNATHTAYGAY AARTAYATHGARMGNCARYTNYTNCCNTTYACNATHACNCARGCNMGNGAYGCNATHATH GARATHATHGARTGGCARTTYYTNGCNMGNGAYGARGGNGARGARAGYATHGARCARGAY YTNGGNTGGGCNCARGAYGARGARCCNGARCCNGCNGARACNGAYTGYTGGGCNCARGGN TCNGTNCCNAARAAYATHGTNYTNGCNCCNACNCCN------------GTNATGGARGAR ATHCCNGARGARGTNGAR---GARATHCCNCARGARGARGARAARGARATHGARCCN--- GARGARGTNAARCARGARCCNCCNGARYTNGAYGAYGTNGTNTCNGARGCNGARGAYATH GCNCARCCNGARAARGAYGAR------------------AGYACNACNACNCCNTCNCCN CCNMGNGGNTCNCARGTNTCNTCNMGNTCNAARTTYMGNCCNTAYAARGGNAARYTNAAR TCNGCNGGNGTNMGNAARATGACNGARTCNYTNGARGARACNGARATHCARATGATHTAY GAYGARATHGTNGCNGCNATGCCNCCNAGYGARGAYAARCCNAGYACNYTNYTNAAYATG CCNGCNTCNTGYACNAGYATHYTNAARGTNCARACNGGNMGNCCNCCNGGNAAYAARGAY GTNYTNTAYGAYGAYYTNGGNAAYGTNATHGCNGTNATGAARYTNGAYCCNGARAARYTN CCNACNCAYAARGTNAAYGTNAARTAYCAYGTNGTNGAYCCNGCNGTNGARGCNGCNCAR GCNMGNYTNGAYGCNATGMGNAARGGNAARTCNACNGGNAGYAARATGMGNAARYTNAAR TCNGTNMGNAAYTTYACNTCNGAYCCNATHGCNGGNGGNTCNAARCCNAARGCNGCNTCN TCNTCNAAYACNGTNGCNCCNYTNCCNCCNCCNYTN------------------------ ---------------------------------ATHGARGARATGGARGTNTCNCAYGGN GTNGTNATHMGNGARGGNGGNMGNGTNAARAARGGNCCNGGNMGNTAYTAYMGNAARYTN GAYATHYTNGARGARAAYCARAARGGNATGAARCCNGTNAGYGTNMGNYTNACNAAYGCN GGNATHACNGTNAAYGAYYTNYTNGAYMGNAAYACNCCNATHYTNMGNCCNYTNGGNGAY TCNTCNCCNYTNCCNCCNATHGTNCCNCARCCNCCNCCNCARCCN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TAYTCNYTNYTNAARGARTGYTGYTTYGAYTTYCAYAARGTN ---CCNCCNAGYGARYTNAARMGNMGNGGNATH---CCNTAYGARCAYGCNTAYGGNTGY ACNACNGTNATHGGNCARCARTCNATHTTYATGCAYTGGYTNATGMGNGAYTTYAARTCN MGNGGNGGNCARATHCARMGNMGNACNYTNAARAAYYTNGARGARYTNTAYGGNGARTTY GAYATHGTNGCNAAYTGYTGYGGNGGNMGNGCNCARACNTTYYTNAAYGAYAARGARTGY TTYCCNATHMGNGGNCARYTNGCNATGYTNAARGCNCCNTGGATHAARAAYTTYTAYTTY TCNGAYGCNGAYGTNTAYYTNATHCCNCAYTTYGAYAARYTNATHGTNGGNGGNGTNMGN CARGCNCAYAAYGCNAGYACNGARGTNGTNCCNGARGTNGARGARAGYATHYTNMGNAAR GCNGARGCNATHTTYCCNGARYTNAARGGNGCNGARMGNYTNCCNGGNTGGGCNGGNYTN MGNCCNGGNMGNACNCARYTNMGNYTNGGNATHGARATGATHAAYGTNGGNGGNAAYMGN AARYTNCCNGTNGTNCAYAAYTAYGGNCAYGGNGGNCAYGGNGTNACNYTNAGYTGGGGN ACNGCNGTNCAYGTNGCNAARYTNGTNAARMGNACNYTNGCN------------------ ---------------------------------------------------TTYGAYAAY YTNGAYGARTTYTCNAAYCCNTTYGARTCNAARAGYAARGTNATGATGGGNTCNTCNCCN CCNATHMGNTCNAAYGCNAAYTCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------AGYAAYCCNGGNACNCAYCCN TAYACNGTNGGNAARGTNATGYTNATGGCNCAYGCNAARGCNTGGCAYACNTAYGAYGAY GARTTYMGNMGNMGNCARCARGGNMGNATHGCNATHTGYYTNCAYTCNATGTGGGCNGAR CCNGAYCCNMGNAGYGTNYTNGAYCARGARGCNGCNMGNMGNCAYYTNGARTTYGARYTN GGNTGGTTYGCNCAYCCNATHTGYGGNGGNGGNGGN---TAYCCNAARGARATGGARMGN CARATHGARMGNAARTCNAARGARCARGGNYTNAARAARTCNMGNYTNCCNAARYTNACN GARGARGARGTNYTNTAYATHAARGGNACNTTYGAYTTYTTYGCNYTNAAYCAYTAYACN ACNMGNYTNGTNAARCAYAARAAYACNCCNTCNAAYCARCCNCAYTTYGARYTNGAYAAR GAYGARGARACNTCNGTNGAYGARGAYTGGYTNAGYCCNGARGGNTCNTGGATHAARGAR GTNCCNACNGGNYTNMGN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGGMGNGGN GCNAAYYTNATHATGACNGTNTTYTTYTTYYTNGCNGCNYTNGCNAAYATGAAYGAYCCN GAYTGGTAYATHTGGGCNCCNATGTAYTTYTTYCCNTCNATHYTNTGYTTYGTNGCNTTY ATHCAYCCNCAYAAYATHGGNAGYCAYGTNTGGCARGTNTGYATGTCNATHGARYTNGGN GTNGCNAGYGCNATGACNYTNTAYCARYTNTCNAARGTNTTYGCNATHTAYGAYGARATG GCNTCNAAYCCNYTNATHCAYGARGARGGNMGNGARATGGGNGGNYTNATHATHATHGTN GCNTGGACNGGNATHTCNMGNTTYTCNCCNTTYCAYAGYTCNAARGCNAARAARAAYAAY GGNATG---ACNGGNYTNYTNGTNGTNGCNGTNACNYTNGCNGTNGTNCCNYTNGTNACN TGGTCNYTNTGYTTYGTNGGNGARTGGCAYAARCAYYTNGGNCAYTGYGCNGGNATGTTY ------------------------------------------------------------ ------GGNGARAARCCN------------------------------------------ ------------------------------------------TAYGTNTGYAARYTNTGY GAYAARTCNTTYAGYYTNATHGGNAAYYTNMGNMGNCAYGARYTNATHCAYTCNGGNAAR MGNCCNTGGAARTGYCARTAYTGYGAYAARACNTTYAAYCARAGYACNTCNYTNAARGCN CAYACNMGNATHCAYACNCARGARAARCCNTAYMGNTGYAAYYTNTGYGARGTNTCNTTY TCNCARMGNCAYGGNYTNATHATHCAYTCNMGNCARCAYCCNAAYGCNAARACNTAYGAR TGYTCNTAYTGYCAYYTNYTNTTYCCNTAYTAYMGNGAYYTNGCNYTNCAYATHCAYCAY CAYACNGGNGARAARCARTAYCAYTGYYTNCARTGYCCNCARAARTTYGTNATGYTNMGN GAYYTNAARATHCAYACNACNATHCAYTCNGGNYTNAARCCNTTYAARTGYTTYYTNTGY AAYAARACNTTYACNMGNMGNATHACNYTNMGNAAYCAYYTNAARGCNCAYGAYGGN--- AARYTNTGGGARTGYAARATHTGYCAYGTNAARTTYGCNCAYCCNGCNAAYYTNAGYMGN CAYMGNMGNYTNCAYATGAAYYTNAARCCNTTYAARTGY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------AARGCNATHGARTTYATGAARTCNGCN GARACNMGNMGNCAYGARTCNGARGARGAYCARTCNGAYGARYTNCCNACNATHACNGGN AGYMGNAARMGNATHAARATGATHCCNGAYACNCCNTCNCCNACNMGN------------ ------------------GARAGYAARGARAAYCCNYTNGCNTTYYTNAARGARTGYTTY CCNAAYAARACNGARGARCAYGTNMGNAARATHYTNACNGCNAAYGAYGGNGAYGTNGAR MGNACNTCNGTNGCNYTNAAYAGYGARAGYAARGAYGCNAARATGGCNGARTCNATGACN TCNCCNMGNAARCCNGARAARACN---TCNAARYTNGCNAARGTNGTNAARGCNCARAAR GCNAAYGGNAGYGCNAARMGNAARGAYTAYGAYATGAGYGAYGAYGARGAYGARTAYGGN GAYGARTAYGAYAGYGCNGAYAGYGAYGAYAGYGARGARTTYGCNAGYAARACNMGNTCN GAYGCNGARAAYATHYTNCARTTYTTYGARGARGCNACNGTNGARGARYTNAAYGCNYTN CARGGNTGYTCNAARAARAARTCNGARYTNATHATHACNYTNMGNCCNTTYACNACNTGG GARGAYYTNTGYGTNAARTTYGAYGGNCARAARGCNYTNTCNMGNGGNYTNATHTCNGGN TGYAARGARATHATGMGNATHMGNAAYACNATHCAYMGNYTNATGYTNMGNTGYGARAGY ATHTCNGARCARATGGARAARGTNGTNACNACNYTNAAYGAYAAYCARACNGARGARATG ACNGAYGAYGARAARAARATHGTNAARTCNCCNGAYAAYYTNTCNACNGTNTTYAGYYTN AARGCNTAYCARYTNATHGGNYTNAGYTGGYTNMGNATHATGCAYGARCARGARYTNAAY GGNATHYTNGCNGAYGARATGGGNYTNGGNAARACNGTNCARGCNATHGCNTTYYTNGCN CAYYTNYTNGARGARGGNGARAGYGGNCCNCAYGTNATHATHGTNCCNTCNTCNACNATH GARAAYTGGYTNMGNGARYTNCARYTNTGGTGYCCNGCNYTNAARGTNATHGTNTAYTTY GGNTCNCARGARGARMGNMGNGTNGTNMGNAAYTCNATHTTYATHGAYGAYGARGARTTY AAYGTNYTNYTNACNACNTAYAAYATGGCNACNGGNGGNGTNGARGAYMGNGTNYTNTTY AARAARTAYMGNTTYCAYTAYGCNATHTTYGAYGARGGNCAYATGYTNAARAAYATGTCN TCNYTNMGNTTYCARAAYYTNATGAARATHGCNGCNGAYMGNMGNYTNYTNYTNACNGGN ACNCCNYTNCARAAYAAYYTNYTNGARYTNATGTCNYTNYTNTGYTTYGTNATGCCNGAR ATHTTYCARGGNAARACNGARCCNYTNAARAARATGTTYTCNATGATHTCNMGNTCNGAR GAYAAYAARAARAGYGGNTAYGARTGGGARAARATHGCNCARGCNAARMGNATHATGAAR CCNTTYGTNYTNMGNMGNYTNAARAARGAYGTNYTNAARCARYTNCCNAARAARACNGAR AARYTNATHAARTGYGARATGACNGAYTGYCARAARATHGTNTAYGAYACNYTNATHTCN AARTAYGCNCARGARATGGARAARGGNGGNGARTCNTCNTCNGGNGGNGCNGTNGGNTAY TTYATGCARTTYMGNAARGCNGCNAAYCAYCCNYTNYTNATHMGNAGYCARTAYTCNGAY GAYATHATHGGNGARATGGCNAARAARATHGCNAARGARCCNTCNCAYMGNGAYMGNGGN GCNYTNCCNAARYTNATHCARGARGAYATGGCNGTNATGAAYGAYTTYGARATHATHGGN YTNTGYMGNCARTAYAARAARTAYYTNGGNAARTAYGARYTNGAYAARTCNGTNATHTGY GTNTCNGGNAARTTYAARAARYTNGAYAARYTNYTNCCNCCNATGAARGCNAARGGNGAY MGNATHYTNYTNTTYAGYCARTTYACNATGGTNYTNGAYATHATGGARCARTAYYTNGAR CARMGNCARCAYAARTTYATHMGNYTNGAYGGNTCNACNCCNGTNACNGAYMGNYTNCAR YTNATHGAYMGNTAYAAYACNGARCCNGAYATHTTYGTNTTYYTNYTNTCNACNMGNGCN GGNGGNYTNGGNATHAAYYTNACNACNGCNAAYGTNATHATHYTNCAYGAYATGGAYTTY AAYCCNTAYAAYGAYAARCARGCNGARGAYMGNTGYCAYMGNYTNGGNCARAARMGNGAR GTNACNGTNATHAARYTNATGTGYGARAAYACNGTNGAYGARGCNATGYTNMGNTGYGCN AAYGARAARYTNGCNYTNGARAARGAYGTNACNGGNACNGGNCCNGAYGAYAAYGARGAR GGNAGYAARGAYGTNGCNAGYYTNYTNAARCARATHYTNAARCARCAYCARCARCARTCN GCNGAYTAYGAYATGGGNATHYTNGAYGTNAARAARCCNYTNGAYTGYACNTGYCARGAR YTNYTNTGYACNCCNAAYATHGTNATGTTYGGNTGGYTNMGNAARMGNAGYYTNMGNAAY AAR------YTNYTNGTNYTNAGYTGGCCNCARGCNTAYGTNATHYTNGCNAAYAARTGY YTNTAYTAYTAYTCNGAYGARATGTCNAARAARGCNTCNGGNTCNGTNTCNYTNTAYGGN TTYAAYMGNATHTGYMGNGCNAGYMGNGCNAARGTNAARAAYGTNGTNTGGGCNTTYAAR YTNGARCAYATHCARCCNGCNATHTCNTCNYTNTAYTTYGCNGCNTCNTCNGARAARGAR ATGGTNAARTGGATGMGNGCNATHAARYTNGARATGMGNGTNGCNAAYGGNATGACNCCN GAYGGNGCNAGYAGYTCNACNGGNGAYGGNGARTCNATHGCNTCNGARGAYTCNTGGGGN TCNTCNGAYTAYAGYTTYYTNGARAGYGGNATHTAYGARACNCCNATHACNTGYMGNCCN ATHTCNATGATGGGNGAY------------------AGYYTNGARGGNGARCCNTTY--- ------------------------------------------GCNAGYAARATHCARCCN TCNGTNGCNGTNTCNCARGGNACNACNGTNACNCCNAGYGCNCCNCCNTCNAGYGAYGTN AARTCNAGYGARGARTAYTGGAARGCNATGYTNTTYGAYGGNACNAARGAYGARGCNACN MGNATHATHACNAAYYTNGCNGARGAYGGNGTNTAYYTNATHMGNAAYAGYGARGAYGAY TCNAARGTNYTNGTNGTNCAYGCNGGNACNCCNAARAARTAYAARATHATGGARCARGAR AAYGGNMGNYTNTCNYTNTCNAARACNGARCCNGAYTTYGARAGYYTNGARAARYTNYTN TAYCAYTAYTAYAGYAGYTGYYTNCCNAGYAGYAGYTAYAARYTNAAYTGYCCNTTYAAR YTNCAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGGCNGAYGTN------ ------------------------------------------------------------ ------------------------------------------------AARCCNGCNGTN CARMGNGAYGGNACNATGATHTCNACNGCNAARGARGCNGAYMGNYTNYTNGAYGGNAAY AARCCNGAYGCNGAYGCNCARACNMGNGGNCARCARAARCARATHGARGAYYTNAARAAY GAYAARTCNGARCCNAARGCNAARAARGCNAARYTNAGYAARGAYAGYACNATGGCNGCN ACNGCNAARGARGCNAARACNATHYTNGCNGGNGARAARYTNGGNGAYACNMGNCARGAY ACN---------AARGCNAARGTNAARACNCCNYTNAARAARYTNACNACNATGGCNMGN ACNYTNGARGARGCNAARAGYGTNYTNGAYGGNAGYYTNGAYGTNGGNGARGGNMGNAAR ACNMGNTCNCARAGYMGNGGNGAYACNCCNAARCCNTCNATGAARAARYTNGGNACNATG CARCARACNGCNAARGAYGGNAARGCNTAYYTNAAYMGNAAYAARGGNAARMGNTCNGCN GCNAARGCNGAYGARGARAARGAYGAR---YTNGCNGAYYTNGARGAYGTNGAYTAYYTN CARYTNCCNGGNGAYGAYGAYGAYTGGYTNTAYAARCCNTCNAGYMGNCARTCNCCNTCN GAYTCNGARGARAAYYTNATHTCNTGGATHMGNCARGAYTTYGAYCAYCCNACNCCNGAR MGNGARTCNTCNMGNAARGCNYTNGTNCAYTTYATHGARGARGCNGCNMGNATGAARMGN TCNGGNACNGGNAARTTYGAYGGNGGNACNTTYACNMGNCCNAARMGNACNTCNAAYYTN MGNGGNCCNYTNCAYGGNGARGGNGAYCARGTNCAY---GCNCCNAAYGTNGCNGAYATH GARAAYYTNGCNAARCARCARGARGARAAYYTNMGNCARAGYGTNACNCCN---AARAAY ACNYTNMGNAAYAARCAYCCNYTNGTNGARGGNGAYAAYGGNGCNMGNACNAGYCCNAGY MGNTTYGAYGTNGARGGNTCNTAYATGAGYCARCAYMGNGGNAGYTTYAGYTCNGAYCAR AGYACNCCNCCNGAYAGYCCNCAYAAYAGYCARCAYTTYCARYTNACNACNCCNAAYGAY GGNMGNGTNMGNAARAAYGTNCCNGTNGGNCARCCNYTNCARTAYMGNTCNCAYAAYTCN AGYGAYTCNAGYYTNGARMGNCAYAGYGTNACNACNGAYGGNAGYGAYGARATGAAYYTN GCNCCNGARGCNATGMGNGCNCCNTCNTCNMGNYTNCARGCNCCNTCNAGYTCNTCNTCN GCNYTNCCNAARMGNGGNYTNTCNGGNYTNGCNCCNCCNYTNGCNAARCCNCARCARMGN GGNGTNTCNCCNCARMGNCARAGYGGNYTNCCNACNGCNMGNMGNCARATHGCNMGNCCN GCNACNGGNCCNMGNTCNTCNYTNCCNCARTTYMGNMGNCCNGTNACNCCNTCNTCNMGN CCNACNCARTCNCARGAYGARGCNAAYTGGMGNGAYGGNTGYTTYATGCCNAAYYTNCCN ---YTNGTNAAR------------------CAYACNATGGCNGCNGTNGGNGCNAAYACN GCNMGNACNYTNAARCARATGATGAARCCNCAYATHCCNYTNATHAARTTYCCNMGNMGN GAY---------GCNCCNAGYCARGCNGGNTCNGCNYTNGGNAAYCCNACNTCNGTNGAY TCNYTNGTNGCNCARAGYATG------------TCNGCNTCNGGNAARGGNAARTCNGCN CCNAAR---CCNACNATHGAYTAYTCNGARYTNCCNACNMGNTTYCAYMGNAARCCNATH TCNATGGARGARATHGARTAYATHGARAARGGNGGNCARGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ACNGCNMGNYTN GCNTGGAAYMGNGAYGTNAARGGNMGNATHTCNAAYACNGAYATHCCNTTYGCNMGNTGG GAYACNGAYMGNATHACNGCNTGGYTNAAYGAYATHGGNYTNAAYATGTAYYTNGTNGAY TGYAARMGNTGGGTNMGNAAYGGNGARCARYTNATGMGNTCNACNCCNCAYGARYTNGAR AARGARYTNGGNATGAARAAYAGYYTNCAYMGNAARAARYTNACNYTNGGNATGCARGCN YTNACNGGNAGYCARMGNGAYYTNYTNGARGARYTNGAYCAYAAYTTYGTNGCNMGNTGG YTNGAYGAYATHGGNYTNCCNCARTAYAARGAYTCNTTYTAYGAYTCNMGNGTNGAYGCN MGNATGYTNAAYAGYYTNACNGTNGARGAYYTNTTYCARYTNAARGTNTCNAAYGARGTN CAYCAYGCNTCNATHMGNMGNGGNATHCARGCNYTNMGNYTNAAY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------TCNAARATHCAYACNCARGTNTCNCCNYTNYTNTTY CARGTNTCNGAYAARYTNTGYGCNGARCCNATGAARAARMGNAARAARYTNGAYCCNGCN YTNGCNGCNGCNAARACNCARAARAARGTNAARAARATHGAYAARGARATHAARMGNYTN TCNMGNTTYGGNAARATHYTNAARCCNGTNGARGARATHGARGTNGAYMGNMGNAARYTN YTNGCNTCNGGNGARMGNAARMGNGCNCCNGCNGTNYTNACNTTYGARGARTCNGARTCN MGNGCNYTNYTNATHAARGARTGGTCNTGYTAYMGNGCNAARMGNCAYCAYGARATGYTN AARCARAGYTCNAARGTNGCNGCNGCNCARCARGARGCNYTNGAYGARYTNMGNGCNGAR TCNGARGARYTNTAYCARGCNGCNATHCARATHGAYGAYAAYYTNYTNCCNYTNAGYTTY GARGGNCCNAARGARACNCCNCCNATHAARGAYTAYAGYGCNCCNGAYGGNGARTAYGTN GAYACNACNMGNAARTTYATGGCNATHGGNGGNGARATGGAYTGGAAYATHGAYATGGAR GTNAAYYTNTTYCAYGCNATGMGNGGNCAYAARCCNGTNGGNGTNAAYMGNCAYTTYCAR ATGATHGCNATHCAYGAYAARYTNAGYTCNGCNGCNAARAARGTNACNTCNAAYGAYGTN TGGCARCAYYTNTCNACNYTNTAYGAYYTNCARGCNYTNAAYGARTCNGARATHGTNCCN TTYCCNAAYAARAAYGGNGAYTTYTCNYTNGGNGAYAARGARYTNTTYGARYTNTGYGGN AARTCNTTYCCNMGNTCNTCNTAYATHAAYACNYTNTCNACNGARCCNGCNAARACNGAR GGNTCNGGNAARAAYATHTCNAARYTNAGYAAYAARCARGAYGGNAARACNGGNTCNCAR ACNCCNAARTCNGARYTNAARAGYGAYCCNAARCCNAGYAGYGCNTCNAARGCNGAYAGY MGNGCNAGYACNCCNTCNAGYGGNMGNTCNGARTCNAARTCNTCNCAY------------ ------------CAYACNAGYAGYAARTCNTCNCAYCARYTNACNCCNTCNAAYGCNCCN TCNCCNTCNCCNAARMGNACNAARMGNACNMGNAAYGTNAAYTCNGCNTCNGCNAGYCCN GCNACNCCNACNGARCCNCARGTNAARMGNMGNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATHGARYTNGARAARYTNYTNGGNMGNAARAAYATGGAY GTNATHAARTCNAARGGNATGGAYCCNAARGGNYTNGAYGAYGAYYTNGAYGAYGAYGAY GARGAYGGNGGNAAYTTYACN---AARGCNGARYTNACNACNMGNYTNGARATHCARAAR GAYGARATHCARTCNYTNAARACNGCNYTNCARMGNAGYYTNAARGCNAARGAYGARGAY YTNAARGTNTAYAGYAARACNYTNGARGAYACNAARCARGTNTTYYTNCARGCNYTNMGN CARATGAARGAYGGNACNAAYYTNATHCARTTYTTYAARTCNACNYTNMGNAARTCNGCN AARGAYAARAARACNYTNYTNGCNGTNGARMGNGAYYTNATHGCNTTYATHGAYGAYCAR TCNGCNCARTCNTAYAARATGAAYGARATGAAYCCNTAYGAYMGNATGGTNGCNCAYMGN GTNGCNGCNTAYTAYGGNYTNGAYCAYAAYGTNGAYCARTCNGGNAARTGYATHATHGTN ACNMGNTGYTCNAARACNMGNATGCCNGAYYTNAARYTNATGGAYATHGGNAAYACNCCN GAYTTY------CAYATHGARCCNAARATHGTNYTNAARAARCCNTCNAGYTTYGAYGAR AARCARACNMGNAAYGCNAARAARGAYTCNTTYGGNCCNCAYAARGCNAARTCNTTYGAR GARMGNCARCARAAYTAYGAYGARGTNMGNGARMGNATHTTYGTNAAYCARGGNCARAGY ACNAGYGGNCAYYTNYTNCAYCCNYTNATGAGYCARMGNAGYYTNGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNYTNTTYTTYAARACNYTN GCNATHYTNYTNMGNAARAARGCNGARAARMGNGARATHACNCARGAYTTYTAYAARGAY TTYYTNMGNAARACNGARGARGAYYTNAARGAYYTNGGNACNATGATHGAYMGNGARAAR GARGARGCNGARGARAARYTNAARAAYGAYCCNAARGTNAAYAARGAYGCNCARAAYYTN GARACNGARATGCARAARYTNCARACNCARTTYAAYAAYAARCARGTNAARYTNCARAAR GAYTTYMGNGAYAARATHMGNYTNGAYYTNYTNMGNGCNTCNGGNATGCCNGARGCNGAY GTNGARGAYYTNATHTCNAAYYTNATGACNAAYATGGCNACNGTNGARGARAARYTNGGN YTNGARCARGCNMGNCARMGNMGNACNYTNGARCARMGNYTNGCNAARMGNAARCARGCN ATGGARTAYCARGARATHGARAARCARGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGGAYAAYTTYTAYATGTCNYTNTGYYTNGCNYTNTTYGCNTGYTGYGTNTTYGGNCAR GAYCCNCCNYTNGCN---GTNAARTTYYTNAAYGAYACNACNGTNGAYGTNTCNGARGGN GCNGARGGNATHGAYTTYMGNTGYCAYYTNAAYMGNGGNCCNATGTTYGTNATHAAYAAY YTNGTNCARATGATH------------------CARGTNGAYCCNAARGAYCCNTCNAAR GARMGNGTNYTNAGYGARTCNGGNAGYYTNGARAGYAARCCNGARTTYTAYAGY------ ------GTNAARATHGARGARTCNAARGCNATGGTNGTNCAYTTYACNATHAARAARGTN MGNCARYTNGAYGAYGGNAARTTYYTNTGYMGNGTNACNTCNGAYAAYCAYAARATHTCN GCNGAR---------------MGNGARATHGTNGTNCAYMGNCCNYTNGAYACNYTNAAR YTNAARTTYGGNGAYYTNGARGCNGTNTCNAARGARGTNAAYGAY------------CCN ATHGARATHGAYCCNGGNAARTAYACNGTNTCNTGYATHGCNGARGGNAGYAAYCCNGGN ACNGARGAYGTNACNYTNACNGTNGAYTCNGAYGCNGTNGTNGTNMGNGGNAARCCNGTN GTNGCNGCNATGGARACNCCNGAYMGNMGNTTYATGACNACNGTNACNGTNGARYTNGAY ATHATGGTNCARAAYTAYGGN---GAYATHACNTGYCARGCNMGN------GAYTCNTCN GGNACNTCNYTNACNACNAARCARACNATHAGYGTNAAYACNTAYGAYCCNATHGTNAGY TGYAAYGAYACNGCNGCNTAYCCNGGNCARGCNAAYCCNACNYTNGTNTGYACNGTNAAY CAYACNGGNATHGAYGTNACNGGNTAYTCNTTYCARGTNGGNGARTCNGGNGARATHATH AARCARGGNGTNGAY---------CAYGCNAARAAYTTYGARGTNACNGTNGARGARGAR TCNGCNGAYGTNGCNATHGTNACNYTNGAYYTNCAYAARGGNGARGARGCNTAYYTNAAY MGNCAYTAYTAYYTNYTNATHGAYATHAARGGNGGNCAYACNAGYAARGARAGYGTNMGN YTNGAYAARGCNGAYGTNCCNGARTCNGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------AARTTY CAYTTYYTNAGYATHGCNATHGAYTCNGAYYTNATHAARAAYAARTTYCAYGGNTTYGAY TTYGGNTCNAARAARYTNCARACNYTNGCNAAYGGNYTNTCNCCNTGYTTYYTNMGNYTN GGNGGNACNTAYGCNGAYTTYATHATHTTYGTNCCNCAYGGNGARACNGARGAYYTNCCN AARTCNGTNGAYTCNTTYGCNAARGAYGARTAYTAY---------GAYCAYTGYGAYTGG AAYGARTCNYTNTCNAAR------GAYYTNAARAAYTAYACNATGACNGGNAARCARTGG GAYAARATGATGAARTTYACNAGYYTNGTNGGNTGGGAYGTNATGTTYGAYTTYAAYYTN TTYMGN---AGYGAYGGNYTNTGGGAYCCNTCNAAYGCNGARGAYYTNYTNAARTAYTCN GCNYTNMGNGGNTAYGARYTNCARGCNTTYCARYTNGGNAAYGARCCNAAYTCNTTYAAR CAYAAYTTYAAYTTYAGYATHCCNGCNGCNACNYTNGTNAARGAYTTYAAYACNYTNAAR GAYGTNYTNGTNAARTAYCCNCARTAYTCNAAYAAYAGYYTNTAYGGNCCNGAYGTNACN AAYYTNAAYMGNCAYTCNTCNTCNMGNAAYTAYYTNMGNGAYTTYGTNAGYGCNGGNGGN AAYCARGTNGTNGAYGARATHTCNYTNCAYCAYTAYTAYYTNAAYGGNMGNATHGCNAAR GCNTAYGAYTTYTAYAAYGTNGCNGTNYTNGAYTCNYTNGTNGARGARYTNACNACNGGN CAYACNYTNGCNGGNGCNAGYMGNATHMGNYTNACNGARACNTCNTCNTGYTAYGGNGGN GGNGCNCCNGGNYTNTCNGAYMGNTAYGTNGCNGGNTTYYTNTGGYTNGAYAARYTNGGN YTNGCNGCNAARTAYGGNGTNACNAARGTNTTYMGNCARACNTTYTTYGGNGGNTCNTAY TCNYTNATHTCNAGYMGNYTNGAYCCNAAYCCNGAYTAYTTYYTNTCNYTNYTNCAYAAR MGNYTNATHGARGGNCCNGTNTTYAAYGCNACNGTNCAYCCNAARACNAARTAYYTNMGN GTNTAYGCNCAYTGY---ACNMGNAAYAGYGGNYTNTAYAARAARGGNGCNGTNACNYTN TCNTAYYTNAAYGTNAARAAYGARTCNGTNCCNYTNAGYYTNGGNCARTTYTTYGAYYTN GAYTAYGAYGCNTAYATHYTNACNCCNGGNGAYTCNGAYGGNYTNAARTCNMGNTTYGTN AARYTNAAYGGNAARACNYTNCARATGTCNGGNTCNTCNYTNCCNCCNYTNGCNCCNGTN TCNCAYMGNGGNACNGTNACNYTNCCNCCNYTNTCNTTYGGNTTYYTNGTNGTNCCNGAY GCNMGNGTNCCNYTNTGY------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GGNATGGGNATGCARCCNCARYTNGCNGGNGTN ATGGGNCARCCNMGNATGGGNGGNMGNGGN---YTNYTNCCNCCNAAYATHATGGCNGGN ATGMGNGCNCCNAARCCNCAYATGAAYMGNCCNCARCCNGTNAAYYTNTTYGCNCARGGN YTNYTNTCNGARGTNGCNAGYMGNATGYTNMGNCCNACNGGNCCNAGYYTNCCNGAYATH GTNGCNAGYATH------MGNGGNCARATGTCNGCNCARCCNATHAAYAAYTCNGCNATH MGNCARTCN------CCNGCNGCNATGGCNACNGGNATGCARGGNTCNGTNATGAAYCCN GTN------GCNATGYTNCARGGNATHTTYTCNTCNGCNAAYAAYCCNCCNGGNCCNTTY CAYGTNCCNCCNGGNGTNTCNAGYTCNGGNCCNGGNYTNYTNGGNYTNCCNGGNCCNYTN CCNTCNGTN---ACNTCNACNCCNGCNACNTCNACNGCNYTNAGYTTYCCNGCNGGNGCN AGYTCNTCNACNTCNTCNAARCCNATGGAYATHAAYAGYYTNYTNAAYAAYYTNATHAAR GTNGGNYTNATHGGNGAYAARCCNAARGCNCCNACNGCNCCNACNGCNTCNACNGTNCCN ACNGTNGTNAARGCNGARGTN---------AARCARGARGTNCCNTTYCCNMGNCCNGCN GGNGARGARAARAARAARAARGARGAYYTNCCNAAYYTNACNGAYTTYAAYCCNAARAAR YTNAARATHATHMGNCARMGNATHATHGARGARYTNCAYGAYGGNATHCARTGYCAYACN TGYTCNGCNMGNTTYACNACNGAYGARCAYGARAARTAYMGNGCNCAYYTNGAYTGGCAY TTYMGNCARAAYAARYTNGARCARGARATGGTNAARGTNGCNAARAAYMGNAARTGGTTY TAYACNATHCCNGAYTGGATHCARTAYGARGARYTNGARGAYYTNGARGARAARTCNMGN AGYGARATHTTYGARCARATGMGNTCNGGNGGNGARCARTCNACNGCNGGNGTNTTYGCN ATGGAYCCNYTNMGNATGMGNACNYTNGARGGNAARGARGTNATHAARAAYCCNGTNGCN TCNGGNGCNGARGGNGARGAYYTNTGYGCNACNTGYGGNGAYCCNTTYGAYCARATGTGG AAYGARGARACNGARGARTGGATHYTNAARAAYACNATHAARGTNGAYGGNAARACNTAY CAYCCNATHTGYTAYGARGAYYTNCARGARACNCCNACNCCNGTNAARGAYGCNACNCAR AAYCCNYTNGARAAYGARATHTCN------------------------------------ ------AARATGGARGARGAYTCNTCNGAYCAYYTNCCNACNGARGARTCNYTNAAYCCN CCNGARGAYGTNAARCCNGCNATHCARGCNYTNGTNGCNACNACNGARCAYGAYGAYAAY TCNATHAARGAYATHAARACNGARCCNGTNGARATHAARYTNGARCCNATGAGYGTNTCN GARYTNGARCARGAYAGYACNAAYGTNGTNATGGARGARGCNAARGGNGTNGARGARAGY MGNCARGARCCNCCNCCNGCNYTNYTNTCNTCNTCNTCNTCNAGYGTNGTNMGNCARGTN ATHTCNATHAGYAARGARGAYCCNAAYTCNCCNTGGGARGTNGAYTCNAAYCCNACNCCN GARYTNTCNMGNACNCCNAGYCCN------YTNAAYGTNCAYACNMGNTCNCAYACNGGN GARAARCCNTAYYTNTGYTCNACNTGYGGNAARGCNYTNTCNCAYATGACNACNTTYAAR MGNCAYAARAARATGCAYACNGGNGARAARCCNCAYCCNTGYAGYACNTGYGGNAARGCN TTYAGYGARMGNTTYAARYTNAAYAARCAYATGGCNGTNCAYACNGGNGARAARMGNTTY CARTGYTCNACNTGYGGNAARMGNTAYAGYACNAAYTTYCAYYTNACNACNCAYAARMGN ATGCAYACNGGNGARAARCCNTTYGARTGYACNACNTGYTCNAARAARTTYTAYTCNAAR TTYAGYYTNTGYTCNCAYGTNMGNGTNCAYGCNGGNTAYAARCCNTTYGAYTGYTCNACN TGYGGNAARAARTTYGTNACNAARGCNGAYYTNAAYATHCAYAARMGNACNCAYACNGGN ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GAYGAYGAY GAYGARGAYGARTTYACNGARGARGARYTNGCNAAYGAYCCNTCNAARMGNATHYTNTGG GCNTCNGARAAYAAYAARYTNGAYGCNGTNACNGARYTNYTNACNGARAAYCCNCARYTN GTNAAYGTNTGYGAYAGYGAYCAYTAYACNCCNYTNCAYMGNTGYTCNTAYAAYAAYCAY CCNGAYGTNGCNAARATHYTNYTNTCNCAYGGNGCNAAYATHCAYGCNAARACNGTNGAY GGNTGGCARCCNYTNCAYAGYGCNGCNMGNTGGAAYTCNGTNGARACNGCNCARATHYTN ATHCAYMGNGGNGCNGAYGTNAAYGCNCARTCNAAYGGNGGNYTNACNCCNYTNCAYATG GCNGCNTCNGARATHGAYAAYGGNCARACNYTNGARYTNYTNYTNAAYAAYCCNTTYATH GAYACNAGYYTNGTNTCNCARGCNGGNGARACNGCNAARCARATHTGYGARMGNTGYAGY TGYCAYTAYTCNYTNTTYGARYTNMGNGAYGARAGYGTNAAYAGYYTNAAYAARYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ACNGAYMGNATGACNTCNMGNAARCAYCAYAGY MGNACNAGYGTNTGYTGYTTYGTNAGYGGNACNMGNTCNGGNTAYYTNTAYCARYTNTCN CCNTTYYTNAGYAARCAYYTNTAYGTNGTNACNCAYAGYGGNATHGARACNTAYACNTCN MGNTGGGCNGCNGTNGGNACNGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TCNYTNMGNCCNAARCARACNYTNAARTTYGAR GGNTGYTTYCARTCNTGYTCNGARGAYAGYGTNGTNCARYTNYTNTCNGGNACNYTNACN ACNGCNAGYGGNGTNMGNAARATGTAYYTNGTNAGYATHCARGCNTCNGCNYTNACNATH TGGNNNCARGGNGAYGGNGAYAAYTGGMGNCCNGARYTNGAYTGGMGNYTNTCNTCNGCN GTNCAYYTNATHGARGCNAGYYTNGTNCCNGTNAGYGAYMGNGTNGTNATHGCNGCNAGY GGNTGGGAYAARACNAGYCCNYTNGTNACNGTNTTYGTNTAYGAYYTNGAYACNGAYACN ACNCAYMGNTTYAAYGTNCCNGGNYTNGAYAAYTGYCCNYTNMGNATHTCNCAYATHCAY YTNTGYGTNTGYTCNTCNTCNMGNGTNYTNYTNGGNYTNACNAGYGAYACNTGYCAYACN YTNMGNGGNATHTCNYTNAGY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AGYATGMGNMGNYTNCCNAARMGNYTNGCNTAYATHYTNMGN TAYGGNGTNMGNAARGARGGNATHGAYGTNGAYGARAAYGGNTAYGCNGAYATHGARGAY YTNATGAARYTNAAYYTNYTNAARCAYTAYTCNAARGAYGARYTNYTNAAYGARATHAAR TCNTCNATHTCNATHMGNCAYACNCARMGNTTYGARTGGMGNGARATHGAYAAYMGNATH YTNGTNMGNGCNGCNTAYTCNMGNAAYTTYGARGARAAYCCNTAYCAYCARGGNACNAAR GTNAARACNYTNYTNGARACNTCNATGACNACNYTNYTNGAYAAYYTNGAYYTNTTYGAY YTNGARGAYTTYCAYGAYGARTAYYTNATHAAYMGNATGATHCAYMGNYTNAARMGNCAR AARGAYYTNACNGTNAARGCNYTNTCNGCNYTNYTNATHCCNACNYTNMGNCARYTNGAY YTNCARAAYGTNTTYYTNACNAAYAAYACNYTNMGNATGYTNTGGACNCARTGYCCNYTN YTNACNGAYYTNAAYYTNACNAAYTGYGGNTAYATHATHACNGAYACNGTNYTNATHCAR ATHYTNAARAAYYTNCCNCAYYTNGARCAYYTNAAYYTNACNGGNTGYTCNCAYYTNACN AGYAARTGYYTNGCNYTNATHTCNAARMGNYTNCCNGGNYTNAARAARYTNGGNATHACN GGNGTNCCNTCNATHACNCCNCCNYTNGTNCARACNTTYYTNGAYAGYGCNAARCARYTN AARTTYYTNGAYGTNTTYTTYATGAARACNACNCCNGARGARTAYAARTCNYTNAARGCN GCNGCNCAYAARYTNGGNGTNGAYYTNGTNYTNMGNTCNCCNTCNGAYTCNGCNYTNGGN GAYACNGAYGAYGTNGAYGARATGTAYGAYGARACNGARGARGAYGCNGARGCNGARGAY GCNGCNGARGCNGARGAYGAYGAYGAYGAYGAY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GTNCCNTAYYTNGGNAGY AARATHAGYYTNATHTCNAARGCNGARATHMGNTAYGARGGNACNYTNTAYACNATHGAY CCNAAYGARGCNACNGTNGCNYTNGCNAARGTNMGNTCNTTYGGNACNGARGAYMGNCCN ACNGAYMGNCCNYTNCCNGCNMGNAAYGARGTNTTYGAYTTYATHATHTTYMGNGGNCAY GAYATHAARGAYYTNCAYGTNTGYGARCCNCCNAARCAYTGYCCNGAYAGY---GGNATH CCNCCNGAYCCNGCNATHGTNAARTCNTCNCARCCNCCNCCNGGNCCNATHCAYTCNGGN CAR---------CARGGNGGNGGNGGNTTYCARGGNGGNCARTCNTAYCARCCNTTYACN CARCCNYTNTTYTAY------CARGGNCARCCNGCNCCNGGNTTY------CCNCCNCAY CARGGNCARGCNGGNAAYACNCARGARGARGGNCCNGCNGTNGARCARACNCCNGARCAR YTNAGYCAYCCNTCNGTNTCNGCNATHGGNACNMGNCCNATHTCNGGNTCNCARAGYTCN ACNCCNCCNYTNAGYMGNAARTCNCCNACNTCNGAYCARGGNGTNCARYTNCARTCNAAR ACNCCNGARAARAGYAGYAAYGARACNNNNCARCARCARCAYGCNCAYCAYCAYCAYCAR CARCARCAYCARCAYCCNMGNGGNCAYGGNGGNGTNMGNCAYGAYGGNGGNMGNGGNGGN GCNGGNGGN---CAYMGNGTNGAYCAYMGNGAYMGNGGN---------GAYAAYMGNAAY GAYAARAAYATGACNTCNTCNTTYGTNMGNGGNMGNGGNCARATGMGNGGNGGNTCNATG MGNGGNGGNCARGGNCAYCCNMGNMGNGGNMGNGGN---------------------GGN GGNMGNTCNTCNGARCCNYTNAARTTYGAYACNGAYTTYGAYTTYGARACNTCNAAYGCN CARTTYGAYAARGARGAYATHGARAAYGARYTNAARAARYTNACNATHTCNGAYAARCCN GTNAAYGGNGARAARACNGARGAYGAYCCNGARATHGARGARGARGARGGNGARGARGAR GAYAAYGGNGARGTNTAYTAYGAYAARAARAARTCNTTYTTYGAYAAYATHAGYTGYGAY GCNACNGARAARGCNMGNGGNCARMGNGTNACNTGGMGNGARGARMGNAARYTNAAYAGY GARACNTTYGGNATHTCNGARAAYTAYMGNMGNAAYTAYMGNGGNMGNGGNGGNTGGMGN ---GGNAAYCAYMGNGGNGGNTGGMGNGGNMGNGGNMGNGGNGGNGGNTAYAAYGGNMGN GAYGGNGGNTTYGGNGGNAAYGGNGGNGGNMGNGGNMGNMGNCCNGARTGGGAYTAYGGN GAYMGNMGNMGNATGGAYGCNCCN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNCAYMGNCAYAAYACNYTNTCNGGN GARAGYYTNAARCARATHGCNGARGGNTGYMGNCARYTNMGNAARYTNCAYGCNCCNTGY TCNAARGTNGAYGAYTAYAGYATHYTNAGYYTNTCNACNAAYTGYCCNAAYYTNGARGAY GTNAAYTTYATGCAYTGYTCNYTNYTNTCNYTNCCNTCNYTNACNGCNYTNACNGARAAY TGYGARAAYYTNMGNTAYGCNAAYTTYCARCAYACNTTYGAYCCNAARGARAAYYTNYTN GTNTTYYTNAGYAARTGYCCNYTNYTNCARGARATHAAYTTYGAYYTNTCNTGYTCNCCN YTNCAYTCNCCNGCNAGYTCNTCNTGYACNTGYAGYTCNYTNTCNMGNYTNCAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------GAYTAYCCNGCNGARGTNGARGTNTCN TAYGARGCNTTYAARTAYGTNGARCCNYTNYTNCCNAARACNACNGTNCCNGARATHCCN GAYCAYTCNTCNTAYCCNACNCCNTCNGGNTGGATHCCNCCNAAYGAYGARATHMGNTCN CARCARCCNTAYYTNGTNMGNMGNACNAARAAYCAYGTNYTNCCNATHTAYCCNAGYCAR MGNGARGTNTGGGGNMGNATGATGCAYCAYGTNACNATHAARAAYATHGARGGNGAYATH TGGAARYTNGARTCNGARYTNMGNCAYTAYYTNCARGARAGYATHGAYGAYGARAAYGTN ATHACNCARGTNCAYGARGTNAGYMGNTGYGTNMGNGTNMGNGGNCARCAYMGNGCNACN ATHGCNGARTTYYTNATGGARAARGGNATGAAYGAYACNGGNYTNTCNGTNGAYATHGTN GGNGAYYTNGARYTNACNTAYATHCARYTNCAYCCNACNACNAARYTNTGGAARGTNTAY AARYTNACNGGNGGNGCNAAYYTNACNCARGAYCCNMGNACNYTNMGNTCNMGNYTNGTN MGNGARYTNCARGCNAARTGGACNATHGGNACNGTNTAYGGNAAYATHGGNTGYAGYTCN GGNGCNGTNTGGYTNMGNYTNCAYYTNGAYAARTCN------------AAYMGNMGNCCN MGNAARAAYGCNTAYATHGCNAARAAYTCNGTNTTYYTNYTNCAYTTYCARGGNTCNCCN TTYYTNATHATHAGYCARACNMGNGTNAARGARATGGCNYTNYTNTCNCARTCNYTNGTN CARGTNTTYCARGCNGCNAGYYTNTCNTAYATGCARYTNTCNGAYMGNCAYGTNYTNGCN YTNGCNGAYATHGCNYTNAARMGNAARCARGARATHTCNGTN---GARCARTAYAARGTN GTNGARGGNAARGARAAYCCNYTNTCNMGNTAYGAYMGNAARMGNAARCARGAYGAYGAY ATHTTYGTNGARATGGAYAAYATGGTNGAYGARAAYAARGGNGARAARMGNGTNMGNMGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATHGGNGTNATH TGYCCNTAYTCNGARCARMGNGAYGARATHMGNMGNAARYTNMGNMGNGARGGNYTNAAY AAYATHGTNGTNAAYACNGTNGAYAGYTTYCARGGNCARGARAARGAYGTNATHATHATG TCNTGYGTNMGNGCNCARGAYGCNCCNCARACNGTNGGNTTYGTNGGNGAYAGYAARMGN ATGAAYGTNGCNYTNACNMGNGCNMGNTAYGCNYTNTAYATHGTNGGNCAYGCNGCNACN YTNAGYAARTCNGARYTNTGGAGYAAYYTNTAYAARGAYGCN------------------ ---------------------------------------------------AGYAARAAR MGNMGNMGNACNTTYGARYTNGARGARCCNACNYTNAARGGNGAYAGYACNCCNACNATH GGNAAYGAYCARGARMGNACNACNMGNMGNCARACNTCNMGN------AAYACNACNCCN YTNGAYGARACNCARGCNACNAARMGNYTNMGNMGNAGYACNTTYGAYAARAAYACNCCN GARGTNCARGGNAAYAARTCNGTN---------------------TCNAARAGYAGYCCN AGYACNMGNGCNATHATHGARTCNATHCARGGNGAYTGYTCNAGYGCNGARMGNAARGAR AARYTNYTNTCNGCNATHGAYAARAARGTNCARYTNAARATGGTNTCNAGYCCNYTNAAY CCNTCNAARACNCARGCNAGYCARATHCCNMGNTTYATGGCNTTYYTNACNAAYAARAAR AARGARAAYAGYAARCCNGTNACNCCNGGNAAYAARGAYTGGAAYAARATHCAYAARAAR GCNTTYTCNAARTTYGAYTCNATHGAYGTNTAYYTNGARAARAARCAYCARMGNAARGAR AAYYTNACNTCNAGYAGYAARAARCARTGGCCNAAYAARTCN---ACNGCNACNAARCCN TCNGCNAARATHATHAARCCNGTNCCNAARGGNACNGAYAGYAARAARGTNTTYAARCCN ACNGTNACNTCNACNAARAAYATHACNTTYGAYTTYTCNAARACN---ACNTCNGARTCN AGYAARACNCCNACNAARTCNMGNYTNGCNAAYACNCCNTCNMGNAARGGNGCNCCN--- ---------------------ATHTCNAAYAARGTNAARYTNAGYGCNTCNACNAAYAAR GGNACNCCNTTYAARTTYACNGGNAAYACN---------AGYTCNYTNAAYACNACNGTN AAYTCNGCNAARAARCCNGCNTTYGAYYTNAARGCNAGYYTNGCNMGNCCNYTNACNTGG AARCCNCAYACNGGNAARYTNCARACNGTNGAYGTNAAY------GGNCAYAAYATHGTN TCNGCNYTNAARCCNGGNAAYGCNMGNACNAAYYTNAAR---ACNMGNAARGTNATGGCN AGYACNAAYMGNCCNATHCARGCNAARAAYGTNMGNMGNGCNGAYMGNYTNGAYMGNMGN AAYAAYCARAARTAYGTNGAYATGATGMGNMGNMGNGGNYTNATG--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGCAYTTY GGNTCNAARTAYGTNTAYYTNGGNAAYGARAARGARGAYGTNGARGARGTNAARGTNTCN GARGTNGAYGAYGTNGTNYTNTCNGAYAGYGAYGTNAGYGAYGAYGAYGGNGARACNTGY YTNYTNGAYATHYTNGAYACNGCNGGNCARGARGARTAYTCNTCNYTNAARGAYCARTAY GTNMGNTCNGGNAAYGGNTTYGTNATHATHTAYAGYATHACNGAYAARTCNAGYTTYACN GARGCNGARGCNATHTTYMGNTGGYTNAARMGNYTNAARGAY---GARGAYTGYTAYGCN ATHYTNGTNGCNAAYAARCARGAYYTNAARGAYCARGCNGAR------GTNAGYCCNGAR GARGGNAARGAYYTNGCNAARAGYYTNGGNATHCCNTTYTTYGARACNTCNGCNYTNGAY GGNTCNGGNGTNGTNGGNGCNATGAARGGNYTNATHMGNATHATHCCNMGNATHGGNAAY GAYTAYAARGTNGTNATGYTNGGNAGYGGNGCNGTNGGNAARTCNTGYATHACNATHMGN TTYGTNAGYAAYACNTTYATHGAYGAYTAYGAYCCNACNATHGARGAYTCNTAYMGNAAR ATGATHAAYGTNGAYGGNYTNACNGCNGCNAGYAARGAYGTNMGNAARGGNGCNAARAAR GCNMGNAARGCNAARAARAARGGNAGYMGNCARCCNGAYYTNGTNTTYCCNCARATGATG CARGAYTCNGCNGCNCAYGGNCCNMGNMGNGGNGGNGGNAARYTNAAYAGYATGTAYAAY GGNYTNMGNGTNCARCCNCCNCCNCCNCCNCAYCCNTCNACNAAYGCNTTYGGNGGNYTN CCNGTNCCNGAYCCNCCNGGNCCN---------------CCNCCNAARGTNAARACNGAR MGNAARACNGAYAGYAAYGTNGTNYTNATHTCNYTNAGYTCNYTNGARGAYGARCCNAAR YTNGTNACNGGNGAYCCNGTNCARTGYAARAARTGYGARGCNGTNYTNACNGARATHTCN AARYTNGARTCNGARGGNGAYAARAARATHTGGAAYTGYGARTTYTGYGGNCAYAARAAY TGYGAYATHGAYATHGGNGARGARGARATHCCNAARGGNGCNATHYTNGAYTAYATGYTN TCNCCNGCNACNGARCCNGCNGARGARGARATGGAYGCNGCNACNTCNGAYGAYCCNAAR AARGARAARACNACNCCNGGNGTNATHGTNTAYTGYATGGAYATHAGYTCNTCNATGCAR GCNGCNTGYGCNGTNCCNGARTCNCARTCNTCNTGGMGNCARGARMGNGGNATHGCNGAY TCNAAYAGY---GTNTCNMGNYTNAAYTGYATHCARYTNGCNGTNGARMGNYTNACNGAR CARATGAARATHGAYCARCCNGARAARCARATHATGYTNYTNGTNTTYAGYTCNACNGTN AGYGTNAARGCNGGNGGNGCNATGGAYATHYTNCCNCARTTYAAYCARATHGAYAARAGY AGYTTYGAYCARYTNYTNGTNATGGGNAAYGGNYTNTGYGARAGYTAYCCNYTNAARCCN ATGGARGARTCNTAYGAYGARTTYGTNGARGCNGTNAARAGYYTNMGNACNACNGGNTGY ACNGCNYTNGGNCCNGCNYTNTCNATHGCNACNGGNTTYGTNAGYAARATHCCNGGNTCN GARATHGTNYTNTGYACNGAYGGNGARCCNAAYGTNGGNGTNGGNAGYAGYAGYGGNACN ATGAARTTYTAYGARAARGTNGGNAARTAYGCNMGNTCNAARAAYGTNACNATHAAYATH YTNGCNGTNGARGGNGCNTCNTGYGAYYTNCARTCNGTNAGYGCNGCNGCNGARCARTCN GGNGGNACNACNAAYAARYTNAAYCCNGCNGARYTNGTNMGNCARYTNMGNCARATHGCN CARAAYGARGTNGTNGCNACNTCNGTNACNGTNMGNTTYTTYYTNCAYCCNAAYTTYGTN TTYGAYGARCCNGARTAYGGNGAYAAYYTNAGYCARYTNGARAARGARGTNGGNTCNGCN MGNAARGARACNGAYYTNACNTTYMGNTTYAARGTNMGNGAYCCNTCNAARAARGAYATH GAYACNGTNCCNTTYCARGTNCARATHACNTAYACNAARAARAAYGGNATGAARTGYTTY MGNATHYTNAGYCARMGNAAYGARGTNACNCARTCNMGNCARCARATGGARGAYAAYATH AGYGCNACNGTNATGAGYGTNTCNACNATGAARACNACNGCNCAYYTNGCNAARCARGGN AARGGNAARGARGCNCARCAYATGYTNAARAAYGTNAARMGNATGGTNACNMGNGGNGCN AARTCNGARGARCARMGNGARGCNAARYTNGCNTTYAAYAAYGARATHGARGCNTGGGAY GAYCARYTNACNTAYAAYCAYGARTTYTCNGARGGNCCNGGNTCNGAYTCNGCNCAYAAY ATGTAYCARCARGCNCARGTNATGAGYTGYCARAARGCNGGNGTNGGNGCNTCNAARATH TCNATGGCNATGAARMGNAARAARATGGAYACNAARGCNAARCARGCNTAYTAYTCNTAY AARAAYGAYYTNGTNTTYGGNACNYTNTAYCCNGCNTAYGCNTCNTAYAARGCNGTNMGN ACNAARAAYGTNMGNGARTAYGTNAARTGGATGATGTAYTGGATHGTNTTYGCNYTNTTY TGYAGYGTNGARACNTTYTCNGAYGTNTTYYTNTCNTGGYTNCCNTTYTAYTAYGARYTN AARATHGTNTTYGTNATHTGGATGYTNTCNCCNYTNACNCARGGNTCNAGYTTYATHTTY AARAARTTYGTNCAYCCNCARYTNGCNMGNMGNGARAARGAYATHGAYGARATGATHGCN CARGCNAGYCARCARGGNTAYAGYACNATHYTNTCNYTNGGNCARAARGGNATHCARTAY GCNTCNCARATGGTNATGMGNACNGCNATHATGGGNCARTCNAARYTNGTNGAYCAYYTN MGNMGNAGYTAYAGYACNAGYGAYYTNACNGAYGAYGGNMGNGCNGTNGTNCCNMGNCAY ------------------------------------------------------------ ------------------AGYTAYAGYTCNTCNMGNATHCARMGNGCNGCNMGNYTNAAY AAYGTNGARGCNACNMGNYTNYTNCARGAYATHMGNYTNGTNTCNATGTCNATHGAYTAY ATHCARGCNAAYAGYGGNAAYAGYAARGARGCNTGGMGNCCNCCNTCNAAYGTNGCNGTN GARGGNGCNGARGAYAARGCNGARGARGGNCCNTGYTTYATGTAYGGNGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CCN ATGCCNGAYATGTCNAAYYTNGCNYTNCCNMGNACNACNACNACNCCNAARCCNTCNCAR CARCCNATHCCNAARAGYGGNTAYGGNGGNTAYAGYAAYGCNTTYGCNTTYGGNCAYAAR MGNTCNAGYAGYTTYACN------ATHGARCARAARGGNATGMGNGARAGYAAYATGTCN TCNCCNAAYAGYTCNTCNAGYAGYAGYAARGAYYTNTGGGAYAAYGTNTCNGARTCNGGN MGNAARCARCCNACNGCNTCNGAYATHGAYGAYYTNCARCARGARGTNCARTCNYTNMGN MGNTCNYTNYTNGCNGCNAARMGNGAYMGNTGGGTNAARYTNCCNGTNGARGAYACNYTN MGNMGNATHYTNAARGGNGARGCNTAYTCNTTYGARATGTAYMGNTCNYTNGCNGAYAAR YTNGARYTNYTNGAYTCNGCNYTNMGNGCNAAYGAYGGNAAYGCNATHACNGCNGTNGTN YTNTTYATGAARMGNACNACNAGYTCNCARATHTTYTCNGGNGARYTNAARAARMGNCCN AARGCNGCNAAYCAYTAYYTNCAYTAYYTNAARGARCAYTTYGARTTYGCNGARTAYATH GAYGTNYTNTGYYTNATGGGNMGNACNGARGARGCNGGNATHTTYAARTTYAARYTNGCN GTNTCNACNAARGAYGTNCAYYTNAARATHACNAARYTNMGNGAYTCNTCNMGNGCNTAY TTYAGYACNGAYCCNTCNYTNYTNTAYGAYTCNTCNYTNGTNCARGARTAYGTNGAYYTN YTNGARMGNCARMGNCCNATHGARGARTCNGAYGCNAARGCNGARGCNGCNGGNAARAGY CARYTNTTYAARGAYTTYCCNMGNAARMGNTCNYTNGTNGAYATGTCNGTNGTNACNACN YTNTAYTAYTGYTCNYTNTAYCAYTTYCAYYTNGCNGARAAYTCNYTNGGNAGYCCNGTN GCNATHCARAARMGNCAYCARATGTCNGARAARCARTAYGCNTGGACNGCNATHAGYGCN MGNGCNAARYTNMGNCARTGGAARGAYATHGARACNATHYTNACNACNAARGGNTGGTTY GGNGGNACNAARYTNAARGCNGTNATHGCNTAYGAYAARATHGTNGGNATHYTNCAYMGN AAYAAYGCNTCNCCNGAYATHYTNGAYAARTAYYTNGCNATG------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------AAYTCNMGNMGNTTYTGYTCNYTNTCNTGYTCNMGNMGNCAYAAY GTNAGYCAYACNMGNMGNGTNGGNYTNTTYAARCCNAARGGNTCNACNAARAARMGNAAR CARATGYTNACNGGNMGNAARGGNTGGMGNAAYTCNMGNGGNAAYMGNYTNCCNTAYTCN GTNAAYAAR---AAYCCNGAYGAYCCNCARGARGAYGCNAGYGARGTNCCNGCN---GGN GAYGARATGAGYTCNTCNAAYAGYACNCARGAYACNAGYTCNTCNGCNGCNTCNCCNCAY TCNGCNYTNGARTTYAAYATGGARGTNGAYGCNACNAAYATHCCNACNACNGAYCCNTCN AARTGGACNGTNATHGARGTNTAYGAYTTYGTNYTNTCNYTNCCNGGNTGYTCNGARTAY GCNGARGAYTTYMGNTCNCARGARATHGAYGGNCARGCNYTNYTNYTNYTNAARGARGAY CAYYTNATGACNGCNATGAAYATHAARYTNGGNCCNGCNYTNAARATHTGYGCNAARATH AAYTCNYTNMGNGTNGAY---CCNCCNTTYCAYACNTCNAARGTNCCNAAYGTNAAYCAY AARAARGAYMGNGCNATHGTNAARCAYYTNMGNTAYMGNGAYCAYGARAARACNYTNAAR CAYTCNTAYAGYCCNGTNGTNGARYTNCCNGAYTAYACNTAYYTNGAYGGNMGNCCNACN GARATGACNAARTCNTTYCARGARAARCARGARAARAAYCAYAARYTNGCNCARCARGTN GTNAAYYTNGTNGAYGARGTNAARTTYGCNCARAAYCAYTTYAARCARCARGARGARGCN AARATHMGNCAYCARCARAAYMGNAARGARTTYMGNYTNAARGARAARTTYAAYAAYGAY TCNAARACNTTYGCNGAYMGNYTNGGNYTNYTNATHAARTCNCCNAAYTCNAAYGAYTCN GCNYTNACNCCNTGGTGGMGNGGNACNCAYGCNGGNGTNATHGAYGTNACNAAYCCNGTN GCNGTNGAYTGGTAYYTNAAYATHACNAARAARYTNMGNGCNGAYTTYAAYGTNGCNTCN TTYAARTTYGAYGCNGGNGARGTNAAYTTYYTNCCNGARATHTAYGGNGTNAARAAYCCN ATGCCNAAYCCNAGYTAYTTYTCNCARYTNTTYGTNCARATGGCNTAYAGYGCNCARMGN MGNCARGARGTNMGNACNGGNTAYMGNAGYCARGARTTYCCNGTNYTNGTNMGNATGATH GAYMGNYTNAGYAGYTGGGGNGGNAAYGCNTAYGAYCCNAGYGAYYTNGAYAARACNGTN YTNCCNGAYCCNGARYTNTAYGTNMGNTGGYTNCARGTNACNGCNYTNATGCCNAGYATH CARTTYTCNATHCCNCCNTGGAARTAYAAYAGYACNATHGTNAGYGTNTGYAARAARTTY ACNGARYTNCAYGARTCNTTYGGNAAYAARYTNGTNGCNYTNGCNACNACNGCNACNACN AARGGNAARCCNATHATHMGNCCNYTNTGGTGGYTNGCNCCNAAYGAYGARGARGCNYTN MGNACNGARTCNCARTTYYTNYTNGGNGAYGAYGTNYTNGTNGCNCCNGTNYTNGARAAR GGNGTNGTNAGYMGNGAYATHTAYYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ATGTCNATGGAYYTNGTNTCNAARTGYYTNGARATGGAR------GAYATHGGNGAYTCN TCNTCNAARAAY---AARAARAARAAYAARYTNAARACNAAYGAYGCNATGCARATHATH AARACNGAYMGNCAYGGNGTNTGGAARGARYTNMGNAARGTNMGNAARAARCARGTNAAR GARATHACNGCNAARMGNAARAARGARAARTTYAARTCNGCNATHGARATHTAYAARGAY AARCAYGAYACNGAYTAYACNGARCARAAYGTNGARGCNYTNYTNAARGCNTCNCARYTN GGNAARGTNAARGAYACNGCNGCNCAYAARATHYTNTAYGARYTNCCNTGYMGNYTNTCN MGNGAYATHCARGAR---GARGTNGTNGARGARCCNACNTCNGTNTTYACNGAYGARGAY TTYGCNAAYTTYGCNAARAAYTAYCAYCCNAARATGTCNATGCCNCAY------GTNCCN CCNATHGGNGGNGGNAAYCAR---CAR---------------------GAYMGNCARAAY MGNAARYTNYTNYTNGARCAYYTNCARGARCARAARAARMGNYTNCARCAYGGNCAYCAY TCNTCNTCNATHAGYCCN---ACNCCNTCNATGAGYACNAGYCCNGCNACNATGYTNAGY AAY---CCNTCNTCNATHCCNGGNYTNTCNGCNGCNGARTAYGCNACNATHAGYAAYCCN GCNCARMGNGCNGCNYTNCARCAYGCNCAYGTNAAYTCNGTNGGNTTYTTYATHACNCAR GAYTCNGCNTTYGGNAAYYTNATHYTNCCNGTNYTNCCNMGNGTNCCNGAYGTNAARCCN GAYACNAAR--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ YTNTCNTCNGARGAYTAYTTYMGNGARACNYTNMGNMGNTAYAARMGNTGYCAYGTNTCN GGNGCNATHACNGCNTAYTAYAARAAYYTNCARTAYGAYAAYGCNGGNGAYGCNGAYATH CARCAYTTYGCNACNGARGAYTCNTTYCCNGGNGGNATGACNTCNYTNYTNGARCCNYTN ATHAARGGNYTNATHAARGGNACNGTNMGNYTNAAYGCNAARGTNACNMGNGTNGAYTGG TCNTCNTTYACNGTNAARAAYGCNMGNGARAARGCNGAYTCNATGGTNACNGTNACNTGY MGNGAYGGNMGNACNTTYAARGCNCAYCAYGTNATHATGGCNGTNCCNYTNGGNCAYYTN AARGCNMGNTCNGGNTCNATGTTYCAYCCNCCNYTNCCNGAYTGGAARYTNGARGCNATH GAYGCNGTNGGNTTYGGNGCNGTNGGNAARGTNGCNGTNCARTAYCAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MGNYTNGAYMGNGARAARCARGARMGNYTNGARYTNGAR--------------- ---------AARAARGCNAARGARGARGCNGAYTGYAARGCNMGNGARGARGCNGARMGN YTNGAYMGNGARAARCARGARMGNYTNGARYTNGARAARAARGCNAARGARGARGCNGAY TGYAARGCNMGNGARGARGCNGARMGNYTNGAYMGNGARAARCARGARMGNGTNAARAAR GARGARGGNGARMGNYTNGARMGNAARAARAARYTNGARATGATHATGAARMGNGTNAAR ACNGAYCCNACNCCNGAYAGYAGYGCNGCNACN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATHGAYTCNAAYGGNCARGTNYTNGARTCNCARTCNCCNTGGMGN YTNTCNTTYATHACNGAYTTYTTYTGGGGNATHATHAAYTTYTTYGTNYTNTTYTTYCAR ACNATGATHAAYCCNAAYAARACNAGYAARGGNGAYAAYTAYACNACNGAYTAYMGNMGN CCNGGNGGNGGNGGNCCNCCNACNMGNMGNATGGGNGGNTTY---MGNMGNGGNGGNGGN GGNATHYTNCCNMGNAARATHCARGCNACNATHATGTGYTCNMGNTGYACNAGYGARAAR TTYCCNTCNTGYGARGTNACNCCNCCNGCNTCNAGYACNTGYGTNGGNTCNGGNTCNGGN GTNCCNGARTCNTGYTCNATHGTNMGNGTNTAYAARAARGAYACNGGNYTNGAYCARTTY ATHMGNAGYTGYTCNAAYTCNCARAARCCNGGNTGYTTYGAYAGYAGYCCNGGNTTYMGN ACNTGYGCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GTNCARAAYGTNCCN TAYTTYAARGAYAARGGNGAYAGYAAYAGYTCNGCNGGNTGGAARAAYTCNATHMGNCAY AAYYTNTCNYTNCAYAAYMGNTTYATGMGNATHCARAAYGARGGNACNGGNAARAGYTCN TGGTGGGTNATHAAYCCNGAYGCNAARCCNGGNAARACNCCNMGNMGNMGNGCNGGNAGY ATGGARACNAARAGYTAYGARAARAARMGNGGNMGNGTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ACNGARACN AARATGGTNMGNCARATHGAYCCNGARACNYTNGAYACNYTNCCNGTNCAYCARTAYACN GAYTAYATHAGYGTNCAYACNGCNACNGCNCAYCCNCAYTTYGAYCCNGAYGGNACNTTY TAYAAYATHGGNATGGGNGTNGAYAARGGNCCNGTNTAYAARGTNATHGCNGTNCCNCCN TCNTCNGARGGNGARAARCCNYTNGAYGGNGCNAARGTNGTNGCNTCNATHCCNGCNMGN TGGAARTGGAAYCCNGGNTAYATGCAYAGYTTYTGYATGTCNGARAAYTAYTTYATHYTN ATHGARCARCCNYTNTGYATGAAYGTNCCNMGNATHATGACNAARYTNYTNCAYGTNCCN GTNGCNTCNTGYATGCARTGGCAYGARGGNTAYCCNACNMGNTTYYTNGTNATHGAYMGN AARACNGGNGARMGNGTNAAYCCNGAYTAYGTNACNGAYAARYTNATGATHTTYCAYCAR GGNAAYGCNTAYGARGARGAYGGNCAYYTNATHYTNGAYGTNTGYGGNGGNGAYTCNAAR ATHTCNGARATHTCNGCNGARGAYAARCARCARTTYATH---------------YTNACN TAYGGNMGNMGNTAYGTNYTNCCNYTNAAYYTNGAYAARACNAARGTNGGNGARAAYYTN GTNCARYTNGARGAYACNAARGCNACNGCNYTNYTNCAR---GARGAYAARACNGTNAAY TGYTCNTAYGAYCARYTN------TCNGAYYTNGCNTTYGAYTTYCCNATGATHAAYTAY AARTAYAAYGGNAARAARTAYMGNTAYYTNTAYGGNATGGAYYTNGAYATHGAYTTYAAR ATGTCNYTNATGAARACNGAYATHGCNACNMGNAAYGTNYTNMGNTGGGAR---GARGAR GGNTGYTAYCCNAGYGARGGNGTNTTYGTNGGNACNCCNGAYGGNCARGAYGARGAYGAY GGNGTNYTNYTNTCNGCNGTNATGGAYMGNGTNAAYGARGAYMGNTCNTTYYTNYTNGTN YTNGAYGCNAARACNTTYGCNGARYTNGGNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ACNGCNTAYGARCAYACN ACNGARACNACNGGNGGNCAYCCNCCNATHAARGCNGAYATGGARTAYGTNAARAGYGTN CCNGGNYTNYTNAARATHGCNGARATHGTNYTNTGYGTNYTNGTNYTNATHTGYTCNTCN GTNCCNTAYTGGAGYCAYYTNGGNGGNGGNTGGGTNCARTTYGTNGCNGTNTCNGCNYTN YTNGCNACNATHTTYYTNTTYYTNYTNCAYTTYYTNAAYGTNYTNCCNMGNYTNCCNGGN CCNTGGCAYTTYATHGARTTYYTNTAYTAYTGYATHGARTGYATHYTNTTYGTNATHGCN GCNATHGTNTGYTGYGTNMGNGCNGGNTAYGCNCCNGCNATHGGNGCNTAYGAYTAYGAY TGYMGNGTNYTNGTNACNAAYTTYCCNCCNCARACNMGNGARAGYGARYTNMGNMGNGTN TTYAARGGNTAYMGNATHYTNGAYATHTGYGTNYTNAAYAAYGGNTAYACNAAYGGNTGY ACNMGNGCNGARATHTAYATGAGYACNYTNTAYGARGCNATGMGNGCNATHATGGAYACN GARGGNTTYTTYYTNGARGAYCAYCAYATHAARGTNATGTCNAGYGARGARGARGAYTAY ATGTCNGAYGCNTTYYTNYTNCARTGYGGNGAYACNMGNCCNGGNYTNGCNCCNAARAAY AARCARAAYCARTAYGARMGNGARGARAARGARAARAARGCNAAYAARCARAAYACNATH YTNCCNMGNAARCARYTNGARAARCAYCARMGNGAYATHGGNYTNAGYACNGGNATHTCN GARACNAGYAARGGNTTYGCNYTNYTNMGNAARATGGGNTAYAARCCNGGNACNGGNATH GGNAARTCNGGNGARGGNMGNGTNGARCCNGTNTCNTTYGARATHAARACNGGNMGNTCN GGNYTNGGNAARGAYTCNGARATGAARMGNAARTCNTCNGARATGAAYAGYATGMGN--- ---------GCNAARMGNAARAARTAYAAYGARAARCARACNGARTCNTTYCARACNMGN ATGAARGAYAARTTYAAYGAYAARYTNYTNGARMGNGAYYTNMGNACNGCNCARAARGCN TGYATHCARYTNGAYCARCARGCNGGNYTNACNGARCCNGCNGARCCNTTYTTYTGGCCN GCNAAYAGYYTNCARCCN---GCNGGNAARACNGARGARGAYGARGGNGAYAAYGARGAY TCNTCNGTNAAYMGNYTNAAYGCNGGNTAYAAYGAYGARTGYGAYGAYGAYGAYYTNGAR ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------YTN TGYTCNGCNTCNGTNGCNATHCAYTAYCCNAARGTNCARMGNCARCCNYTNACNMGNAAY YTNTCNTTYTCNACNACNMGNGGNTCNGCNATGAGYGARGCNAARTTYMGNTCNGGNTCN TCNGGNCCNAAYGGNYTNGAYYTNGCNAARAARAAYYTNCAYGCNGCNGARTTYYTNCAR AAYGTNGTNTAYYTNAAYYTNCARYTNTCNGARGAYGARAARATHCARMGNTTYAGYACN YTNTCNYTNYTNTAYAGYCARATHGGNTTYTAYMGNAARGCNGCNTTYTTYAARMGNGTN GCNGCNATGCARTGYGTNGCNCCNAAYCARAARCCNGGNTGGATHCARTGYTAYAAYYTN YTNYTNCARACNYTNGAYGGNTAYMGNATHCCNATGGAYCCNMGNAARTTYCCNGAYGAY CAYACNAGYGGNTGGCCNGTNGTNCARYTNMGNGTNYTNCAYGARYTNGTNTAYTCNGCN MGNMGNATGGGNAAYCCNGCNGTNGCNATHMGNCAYATGACNTTYYTNYTNCAYACNATG YTNGAYCAYYTNTCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYGARTGYGAYATHTGYAARGARGARGGNMGNYTN AARGARCCNYTNMGNTGYTGYMGNAARTTYYTNTGYAARGARTGYYTNTCNAARYTNCAR MGNTGYCCNTAYTGYCARGARGCNTTYGGNATHYTNCAYGGNGAYCARCCNMGNGGNTTY ATGACNGCNAARAARGAYCCNCAYATHCAYYTNGAYGGNTAYAARAARCAYGGNACNTAY ATHATHAAYTAYTTYTTYAAYGARATHTCNTAYACN------------------------ ---------------------------AARCAYTAYYTNYTNATG--------------- ---------------YTNGCNTTYMGNMGNMGNYTNACNTTYACNAARGGNACNTCNMGN ACNACNGGNAARGAYAAYMGNATHGTNTGGAAYGAYATHCAYCAYAARACNTCNYTNCAR CCNAAYAAYGTNTAYGGNTAYCCNGAYGAYCARTAYYTNAARMGNYTNAARTTYGARYTN CARTCNAARGGNGTNACNMGNAARAGYATGACNAARAGYGARYTNACNGAYATHGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GARGGNAGYGARGGNTTYCAYAGY CARGAYMGNGAYGTNCAYGARTCNTTYACNTCNYTNCAYCCNAGYGCNAGYGARYTNAGY ATHGAYACNGAYTTYACNGCNCARTGYTAYMGNTGYGARTTYTAYGGNAARGARCAYTTY AAYTAYTAYGGNYTNGAYGARAARYTNGGNCCNATHGTNATHTCNYTNAARGCNGARACN GAYGCNCCNAAYAAYGTNAAYGTNATHGTNMGNACNAARYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ACNGAYGARATHAARTCNMGNYTNGAYAAYATHAAYACNCARGCNGAYGTNGTN TGYGARYTNAGYGCNGAYMGNYTNCARCARYTNATGGAYCAYCARTAYGGNATHGCNGTN ACNAAYAARTTYGCNYTNTTYATHGAYGARGAYGARGAYCCNYTNGAYGCNATHTCN--- ---------------AARATHAARATHAARAARGAYGTNGARAARAARACNCCNAARCCN AARAARAAYAAYTCNYTNATHGARGAYAARAARCCNGCNGCNCCNGARAAYGARATHGCN AARAARAARGARGGNGGNGAYAARCCNGCNCCN------MGNATGGARMGNGGNAARGGN AGYGCNMGNAAYMGNGARCCNMGNGARYTNMGNGARAAYGAYGGNGARAARMGNCCNCCN MGNMGNCARTTY------------------------------------------------ ------CCNMGNGAYAAYAARGAYGGNMGNGTNGGNGAYGARAAYGTNCCNCCNGARTTY AARGAYMGNCCN---GARGGNGGNTTYAARAARMGNGARGAYMGNGGNGGNGARMGNGGN GGNTTYGGNGGNGARMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNMGNGGNGGNMGNGGN GGNGARMGNGGNGGNGAR---------------MGNGGNGGNTTYGGNCCNMGNGGNGAY MGNAARMGNGARTTYGAYMGNCAYAGYGGNACNGAYMGNACNGGNATHAARTCNGTNGAR AARAARGARGGNGGNGGNGCNCAYAAYTGGGGNAGYTTYAARGAYGAYATHGARGARCAR GGNMGNGTNAAYCCNGCNGAYGTNTCNACNGARTGGGGNAAYCARCARGARAARCCNGTN ------------YTNAAYGARAGYGCNGARGGNGARGCNYTNACNGARGARGAYGCNCAR GCNGCNGARATGACNYTNGAYGARTGGAARGCNYTNCARAGYCARGCNAAYCCNGCNAAR CCNAARTTYAAYATHMGNCARGCNGGNGARGGNGTNGAYTCNGCNCARTGGAARGGNGGN GTNGARTAYCARAARAARGTNGARAARTCNGAYACNGARGARGGNGAR---------AAY GARGAYGCNGARCAYGAYCAYCAYAAYMGNGTNAAYAARCAYGTNGTNACNGAYATHMGN ATHACNTTYAAYGAYAAYCCNMGNMGNGGNMGNGGNMGNMGNGGNGGNGGNMGNGGNGGN ATGGAYMGNGGNGGNGGNGGNGGNMGNGGNGGNGGNGARMGNGGNGCN---ACNGGNGGN GCNCCNMGNGGNTTYGGNGGNAAYAARMGNGARTCNGCNCCNAARTTYGAYGAYGARTCN GAYTTYCCNTCNYTN--------------------------------------------- ---------------------------------------------------TTYGTNCCN AARTCNACNGGNCAYAAYTCNAGYTCNCAYGCNGGNGTNCCNGTNGAYYTNGAYAAYGTN TGGAGYATHMGNAAYGTNTCNYTNGGNACNACNAGYCARTCNGTNMGNTCNGARCCNGTN TCNTTYAARCCNGARGTNYTNTCNAARACNACNCAYTCNTCNTTYTAYTCNMGNCAYGGN GGNATGAAYGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------ATGGCNGARAARMGNTTY TTYYTNATHGGNATHAGYGGNGTNACNAAYAGYGGNAARTCNAGYATHGGNTCNATGYTN TCNAARGCNYTNCCNAAYTGYMGNTGGATHTGYCARGAYCAYTAYTTYYTNGCNGCNGAY GAYCCNMGNGTNGARYTNGAYTCNAGYGGNMGNCARAAYTGGGAYACNYTNAGYGCNYTN GAYATGGAYACNATGYTNGGNGAYGTNTTYTCNTGGATHGARAARCAYAARYTNATHGCN TCNCCNTCNCARGCNTTYYTNATHGTNGARGGNTTYACNATHTTYAAYCAYMGNCCNYTN TCNAAYYTNTGYGAYAARAARTTYTTYYTNCARGTNGAYGARAARACNTCNTAYGARMGN MGNMGNAAYMGNGTNTAYGAYCCNCCNGAYGGNCCNGGNTAYTTYACNGARACNGTNTGG CCNATGTAYYTNAARAAYYTNAARGAYYTNGARGAYCARACNGAYATHGARTAYGTNGAY GGNYTNTTYGAYYTNGAYACNYTNTAYCARCARGTNYTNAGYMGNGCNTCNAARYTNTGY GGNATHCCNYTNACNACNYTNTGGGAYAARGTNMGNGGNGAYCAYCCNYTNATHCAYGAR GARMGNACNGARYTNTCNGGNACNGARGARGTNCARYTNGTNAAYTGGATHAAYGARATG AAYMGN------GTNMGNTAYAARGGNAGYAARCARMGNGTNAARGAYGCNAARGCNCAR GTNGAYAARAAYAARMGNTTYATHTCNAARAARGAYAARMGNAARAARTCNCCN---TTY YTNGGNGTNGTNCARGARGAYAARAAYATHYTNGCNGAYAARCCNGTNGAYAAYGTNTGG GTNMGNAARTTYTAYCCNCARCCNMGNTTYTCNATHGARGARGCNYTNAARMGNCAYCAR GGNTTYGCNCARCCNGCNATGYTNGAYAAYYTNGARGGNTGGGCNTAYYTNGAYATGYTN YTNGAYTTYMGNACNAARAARCARACNAARTTYTCNAARAAYATHMGNTCNACNYTNYTN YTNCCNCAYCCNTTYAAYTAYGGNCCNCCNCCNTCNATHYTNGTNTTYTGYAARGARGAR GARCAYACNAAYYTNGCNATGTCNYTNGGNGCNAARCAYGCNGGNTCNCCNGCNGARGTN ATHAARATGYTNGARAAYGGNGTNYTNAAYCCNAARGAYTTYACNCAYATHYTNGCNACN GCNGAYTGYGGNACNGARATHATGCCNGCNMGNTCNTAYTTYMGNGAYAARTTYCCNCAR AARAAYAARGGNAAYYTNGGNACNGAYYTNAAYGCNATGTGGACNYTNTTYTAYMGNGGN TAYACNTAYGARTCNCAYAAYYTNACNGAYGCNCARGGNAARYTNCARGTNCCNYTNGGN CARYTNAARCARCCNGTNGAYGARYTNGTNGCNAAYTTYGARGCNTAYGTNGARGCNATH TGYAARCAYMGNAGYATHGCNYTNGGNCCNTTYATHCARTCNATHAAYATHGTNGCNCCN CCNTCNCCNGARGARTTYYTNGTNAARGTNGARGAYTAYGTNCCNGGNTAYAARAAYGAR GTNGTNGAYTCNGAYGAYGARGAYGTNGCNGAYGAYGAYGAYAAYAGYGAYAGYGAYACN CCNTCNAAYAARCCNCCNCCNGGNACNYTNTAYCARGTNGARGCNACNCAYMGNTAYGCN GGNGARGAYGTNGAYGARYTNAAYTTYGAYCCNGGNGARATHGTNTAYGTNGTNTCNTTY GAYAAYCCNGAYGARCARGAYGAYGGNTGGYTNATGGGNATHMGNCARTCNAAYGGNATH AARGGNGTNTTYCCNGARAAYTTYACNAARMGNATH------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---CAYGAYYTNTCNTCNGCNAAYGTNCAYATHATHGCNTCNYTNCCNGGNMGNCAYACN YTNAAYAGYAARCAYCAYTGGGGNCAYYTNAARYTNAARAARGTNYTNYTNGARCARGGN CCNGAYCARAGYYTNGTNMGNAAYTGGCCNATGGTNGGNCARTTYTCNAGYATHGGNTCN YTNGGNGCNACNAARGAYYTNTGGYTNYTNAGYGARTGGGGNCARTCNGTNTCNCARTGY AARAARGCNATGTCNAGYTCNATHGCNGCNTCNAARYTNCAYYTNATGTTYCCNTCNAAR GAYAAYATHMGNGTNAGYYTNGARGGNTAYAAYGGNGGNGGNTGYGTNCCNTAYAGYATH MGNACNGCNTCNAARCARCCNTGGYTNACNCCNTTYTTYAGYCARTGGAARTCNGARGGN MGNGGNMGNTCNMGNGCNGTNCCNCAYATHAARACNTAYACNMGNTGYTCNCCNGAYGGN TCNCARGCNGCNTGGTTYYTNYTNACNAGYGCNAAYYTNTCNAARGCNGCNTGGGGNTCN YTNGARAARACNGGNAGYCARYTNATGATHMGNTCNTAYGARATGGGNGTNYTNTTYYTN CCNTCNAAYTTYGGNTGYAARAAYTCNTTYAAYGTNAGYAGYCAYACNGARCARGTNACN GAYCCNGAYMGNAARGTNTTYCCNYTNCCNTAYGAYYTNCCNCCNACNACNTAYGTNAAR GGNTCNAARAARTCNGTNGARYTNTTYTAYGAYGTNGTNTCNCCNTAYTCNTGGTTYGCN TTYGARGTNATGTGYMGNTAYCARACNMGNTGGAAYATHAAYYTNAARYTNAARCCNTTY TTYYTNGGNGCNGTNATGAARGCNTCNGGNAAYMGNCCNCCNGCNATGGTNCCNAAYAAR GGNAARCAYAGYATGGTNGAYGTNGARMGNTGYGCNCARTAYTTYGAYACNCCNYTNATH ATHCCNGCNGAYCCNGCNCARYTNATGTTYGTNAARGGNACNYTNAARGCNCARMGNTTY YTNACNGCNYTNGAYATGAAYTAYCCNGAYAARGTNGARCCNGTNTCNMGNGARTTYTGG ATGMGNGGNTGGAAYMGNGAYGARGAYYTNTCNGAYGAYTCNAGYATHACNGARGCNGCN ACNAARGTNGGNYTNAGYCARAARGTNGTNGARGARATGYTNTCNYTNGCNCARGAYCAR ACNGTNAARGAYMGNYTNAARYTNTTYACNGARGARGCNYTNGARATGGGNGCNTTYGGN TCNCCNATGATHGTNACNGAYGTNAAYGGNAARAARGARTGGATHTTYGGNAGYGAYMGN TTYCCNATHYTNGCNCARATHYTNGGNMGNATGGAYAAYGGNYTNTGGAARATGTGYGCN ACNGTNAAR---GGNCAYACNGCNTGYGTNACNTGGGGN------GAYACNATHCAYGTN GGN---------------------GAYTGGATGAARGGNGTNCARGCNATGGGNATHATG GGNATHYTNGTNACNTTYGCNGGNGCNATGYTNTCNYTNATHAAYYTNGTNGTNGARAGY MGNGGNGAYMGNATGMGNYTNTTYCCNTTYATHATHGGNGGNTGYTCNTGYYTNGGNGGN GTNTTYATHYTNTGYGGNGAYATHATHGTNGCNGCNGARTAYGAYAGYGGNYTNCCNGGN CARTCNTCNGARACNYTNTCNCCNYTNGTNYTNGARATHATHAGYAGYGARYTNTAYYTN AAYTGGGGNTTYGGNYTNGAYATHGTNTCNGGNATGTGYGCNATHYTNGGNGGNATHGTN CAYATHTTYGCNGGNMGNTAYACNYTNGCNGCNGAYGAYTAYTCNTCNACNACNAAYGCN GCNMGNGCNATGGTNGTNTCNGCNATHGCNGTNGGNATHTGGCAYAARGAYGCNATHCAR MGNMGNGTNGAYGGNYTNTGGGAYTAYYTNMGNGARGAYYTNYTNTTYCARTCNGCNCAY TAYGARACNYTNTAYGTNACNGTNGTNTAYACNGCNYTNATGATHYTNTAYCCNTAYGCN ATGCAYCAYATHCCNTAYTTYCARMGNTTYAARGTNTCNAARGARGTNAARTAYGTNAAY CARACNGTNYTNGGNATGGGNATGGAYYTNGTNTTYCAYYTNGCNCCNYTNYTNGTNGCN GAYATGYTNATHATHAARMGNTAYCCNGGNGTNCCNTAYTCNGARATHGCNATHMGNAAR CARGAYTGGGTNGTNMGNACNMGNCCNYTNCCNCARGARTCNCCNAAYTTYATHGCNATG TGYYTNCAYGTNGCNGGNAGYGTNTTYYTNTTYGAYGCNTTYTTYACNYTNGTNCAYTAY GCNATGCAYMGNAAYMGNTAYYTNTAYAARTAYTTYCAYTCNCARCAYCAYGAYCAYGAR GTNGTNCAYGCNCAYGTNACNAAYCARYTNTCNGTNGTNGARMGNGGNYTNCARGTNATH TCNGCNCAYTAYGCNYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GCNTGYATHGAY YTNACNGTNGAYATHGGNGGNGAYGARGTNATHGAYYTNACNAAYCAYCCNAAYYTNATG GAYTCNCCNATHGTNATHATHAGYCCNACNGAYAAYGTNGGNCCNATHMGNMGNMGNMGN GGNAGYGGNMGNMGNGGNGTNMGNMGNTCNAAYYTNTAYAAYMGNTCNAAYMGNCCNGAR MGNTCNCCNYTNTCNTCNCCNTCNYTNGAYATGCCNTCNTCNTCNGGNYTNMGNMGNACN AAYATHGARATGGAYAGYGAYGARGARYTNCCNGAYYTNCCNTTYGAYATHCCNAARGCN AGYGTNGARGCNAAYGCNAAYTAYGTNAARTCNCCNGCNYTNAARATHACNTGYCCNGTN TGYYTNGAYGAYTTYAARCARATHAARAGYAGYAAYMGNMGNGTNATGTCNACNATHTGY GGNCAYATHTTYTGYGARGARTGYATHACNAAYGCNATHMGNTCNYTNAARTCNTGYCCN TCNTGYMGNAARTCNYTNGCNYTNAAYAARATHCAYCCNATHTTYYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------MGNCCNTTYGTNTGYGAYTGYGGNMGNGCNTTYGCNMGNAAYGARGARYTN ACNMGNCAYCARMGNATHCAYTCNGGNTAYAARCCNCAYMGNTGYCAYATHTGYTGYAAR YTNTTYGGNMGNAARGAYCAYYTNACNAARCAYTCNAARACNCAYYTNCAYTCNACNGAR AARAARGTNCAYACNTGYAGYGTNCCNAAYTGYGGNCARAGYTAYACNMGNTCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARTCNAARGAY TCN---------------AAR---GAYATHCAYATHACNAARATHMGNMGNATHGARAAY GCNAARYTNTTYYTNAARTAYYTNTAYMGNMGNAARTTYACNTAYGAYGAYATHGTNCAR AGYCAYMGNAARTGYAARAAYGTNGGNGARYTNMGN---AAYAGYGGNGGNGAYGTNAAR ACNATGAARTAYYTNCCNGAYGARATGAARAARGARYTNGTN---AGYGAYGTNAAYGAR YTNTAYYTNTTYTAYAGYTCNAAYGTNGARAGYMGNACNAARATHTGYGAYCARGGNATG AGYGAYYTNCAYGTNAGYGGNGCNAARGTNTTYGGNAARGGNATHTAYYTNAAYGARATG GCNGGNCARACNGGNCAR---GGNGAYTCNCCNTCNATHTTYCARTCNATHAARAARAAR TTYAGYATGTTYYTNACNMGNGTNATHATGGGNGAYGTNTTYYTNTGYGGNAAR------ ------------------------AAYCAYGARAGYTTYACNACNGGNCARAARYTNMGN MGNCCNCCNTGY------------------------------------------------ ---GTNGCNTGYCAYAARGAYYTNCAYCAYTCNGTNATG--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------TTYMGNAARGTNTTYCARGAYGTNGARMGNGAR GTNATHCAYCCNYTNTGYCARGTNCARGCNGTNTGYGARAAYGARAARCARMGNAAYYTN AARAARACNATGAARAARTGYTGYTAYGARATGYTNGCNYTNYTNMGNCCNGARGTNGAY YTNCARAARGTNMGNCAYCCNGARTGGGARGGNAARGTNYTNACNMGNGARCAYGGNYTN TTYTAYGGNYTNATHAGYYTNATHCCNATGAGYGTNGARMGNYTNACNACNATHGAY--- ------------------------------------GGNATHAGYACNTCNAGYGGNATH CCNGAYTTYMGNTCNCCNGGNACNGGNYTNTAYGAYAAYYTNAARCARTAYAAYATHCCN TAYCCNGARGCNATHTTYGAYATHGAYTAYTTYACNTAYAARCCNAARCCNTTYTTYACN YTNGCNAARGARYTNTAYCCNTCNGGNAARTAYAARCCNAAYTAYATHCAYTAYTTYTGY MGNATGYTN--------------------------------------------------- ---------------AARAARATGATGATHCCNAARCARYTNGGNTGYAARYTNACNACN GARAGYYTNTCNYTNATHAARTCNAAYGARMGNATHGAYMGNAAYAAYMGNGTNTGGGAR GARGGNGARGTNCCNTCNTCNCAYAGYGGNGAYTCNGTNAARGARGAYAGYAAYTCNGAR ---GAYGGNGGNYTNCCNTCNGARACNGGNTCNATHAAYTCNGAYCAYGARCCNTGGACN TCNCARTCNTCNAARCAYAARAAR------AARCAYAARCAYAARCAYAARAARAARAAR AARAARAARTCNAGYAARGARACNGAYMGNAARGARAARGARMGNAGYAAR--------- ------GARAARAGYCAYAGYCAYAGYMGNGAYAARGAYGTNTCNAGYGCNATHTCNAAY GAYGCNAGYGARAARGARAGYGCNGAYATGGAYAARGAYGGNATHAARGTNGAYAARMGN AARGGNAGYGARAARGARAARAGYAARGGNAARGGNAGYGAYTCNGARAGYTCN------ ---------------------------------AARMGNGARGGNAARTCNTCN---GAY AARGAYAARTCNGARAGYAARMGNAARGARAARGARAARAARMGNAARCAYGAYMGNTCN MGNTCNMGNACNCCNAARMGNYTNAARMGNTCNAARTCNMGNTCNMGNTCNCCNAARMGN TCNAARMGNAGYTCNAGYCCNMGNMGNAGYMGNTAYAAYGARTGGGAYGCNMGNAGYTAY AGYGAYAAYGCNAARAARTTYAARGAYGGNCCNTCNMGNTCNMGNTCNMGNTCNCCNAAR MGNMGNMGNTCNCCNGAYMGNGAYYTNMGNYTNCARATHGAYAARACNAARYTNMGNAAR ATHGCNATHGCNAAYGCNYTNAAYACNATGAARTCNGGNCARTCNGTNCARGTNCARYTN GAYATGCCNGCNGTNAARTCNGGNGGNAARTCNGTNGARGARYTNACNGAYTTYTGYAAR MGNATHTCNGARAARGAYCARGARAARCARGAYCAYGCNGTNAGYGAYAGYGAYGARCCN GCN---GCNCARAGYGAYGARGARGARCCNYTNATHCAYCAYCCNTTYAARGTNMGNGAR CCNACNTCNAAYATHATHATGAAYATHMGNAAYGCNAARCARYTNCCNGTNATGACNCCN TCNGARAARCARGCNCARCARTCNACNYTNMGNYTNGCNTTYCCNGTNTCNAGYGGNTCN CAYCAYMGNGCNAGYGARTCNGARTGGGTNCCNGTNGARAARACNACNGCNCCNCCNACN TCNACNACNAAYMGNTAYACNACNTCNCARGCNTCNTCNTCNTCNACNCCNTCNGARCCN CARCCNGGNCCNTCNAARAGYATHTTYCCNGARGTNACNGARAARGTNGAYATHGGNGCN ATHATHTCNGARMGNYTNCARGCNGTNMGNAARYTNGARTCNAAYCCNTAYGAYGTNCAR GCNYTNTGYACNATGCAYAARGCNCAYGARMGNGCNAGYCARTGGGTNCARTCNAARCAY YTNCCNGGNCARTTYACNGGNAGYACNGGNGCNCARGTNATGTCNCARCARGARATHYTN GGNGAYAARMGNCAYCARGCNTGGGCNAARAARACNCARTTYACN------------GCN GCN------------------------------GCNCCNYTNMGNGGNGGNGARGGNYTN GGNAARAAYTGYGARGGNAGYYTNGARCCNYTNCARYTNGAYATHAARATHGAYMGNAAR GGNYTNTCNACNGCNGCNGAYAAYCCNMGNGCNMGNTCNCARGCNGCNCAYGTNCCNAAY AAYAARGAYYTNTCNCAY------------------AARCAYCCNGTNTCNGCNYTNATG GARYTNTGYAAYMGNMGNMGNTGGGGNCCNCCNGGNTTYACNGTNGTNTCNGARGAYGGN CCNGCNCAYAARAARTAYTTYYTNTTYAARGTN--------------------------- ------------------------------------------------------------ CARAAYTCNACNCCNATHAARTTYGAYAAYAGYMGNAGYATHGAYGTNTAYMGNYTNAGY GTNGARMGNCCNAGYCAYAAYGAYTGGAAYYTNCAYATHMGNGAYGTNMGNGAYAGYGAY CAYGGNGTNTAYGCNTGYCARGCNGAYACNGAYCCNATHACNACNMGNATGGTNAAYYTN ACNGTNGCNMGN------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYACNTCNYTNMGNATHTTY ACNTTYCCNATHAARGAYATHCARACNTGGAGYGARGCNCARGTNTAYGAYGGNCARATH YTNTTYGARGTNTAYGGNYTNATHGCNTCNGGNCCNACNGAYACNGARTCNGGNYTNGGN AARGARTTYTAYYTNMGNGAYCARTCNGCNACNATHCARTGYGTNTTYTAYGARATHGAY MGNAAYYTNCCNGGNYTNACNAARGGNCARGTNCAYMGNATHGTNGGNTCNYTNGAYAAR AGYAARCAYMGNYTNCAYGTNGTNTCNATHMGNAARGCNGAYAARGARGARMGNCARGCN TGYCARAARGCNACNGARGTNTCNYTNCAYGARATGGAYTCNYTNACNMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------YTNGTNGTNCARGCNGARGARYTNGGNTGY GARGGNAARGTNGARGARGCNCARGGNGTNATGAARYTNGTNGARCARYTNAARGAYGAR MGNGARCARGARGCN------MGN---CCNATGAGYGAYGAYGGNGGNCCNYTNATGAAR CARATGGARGTNTGYGARGTNTGYGGNGCNTTYYTNATHGTNGGNGAYGCNCCNCARMGN CARGAYGARCAYYTNATGGGNAARCARCAYGCNGGNTAYGCNCARGTNMGNGCNGARATH GAYMGNMGNAARACNAARGTNMGNGAYGARATG---------GARGCNACNGARACNAAR YTNMGNACNGARMGNGARGARMGNGARAARGARMGNCARATGGARMGNGAYGARMGNMGN MGNAARGARMGNGAYMGNGAYMGNGAYCARGAYMGNGAYMGNGAYMGNMGNMGNMGNAGY MGNTCNMGNAGYMGNGAYMGNMGNAARGAYMGNMGNMGNTCNMGNAGYMGNGARMGNMGN MGNMGNMGNAGYTCNAGYMGNGAYMGNMGNATHMGNMGNAGYAGYAGYCARAAYMGNGAY MGNAARMGN---------AGYTCNAGYMGNAGYAARAARTCNMGNMGNTCNTCNAGYMGN GAYMGNAARMGNGAYAGYMGNCAYTCNMGNGAYACNGGNTCNMGNAGYMGNAARMGNGAR MGNAGYMGNGAYMGN------------------GARTCNGARMGNAAYGGNAAYGGNAAY ---AARGARGAYCARMGNGAYGAYGCNMGN------------------TGYCARATHACN GAYAAYACNYTNGTNGGNGCNTGYCAYGAYGARYTNATHAARYTNATHTCNGCNCAYYTN GAYGGNGGNGGNGTNTAYAAYTGGMGNACNYTNYTNGGNYTNTAYAAYTGGACNTAYAAY GARYTNAARYTNTTYGCNAAYAARGTNCAYGAYCAYCAYTAYTTYMGNCAYATHYTNGAR YTNCCNGAYTTYCARGARTAYAAYATHGGNCARYTNAARGARGAYYTNGAYAAYATGCCN AARAARAAYACNYTNAGYGAR---------------------------ATGGAYTTYGAY TCNTCNTCNAARTTYATHGCNTCNYTNGCNMGNTTYYTNCARTCNYTNTGYAAYGGNTAY GTNGARTTYGAYAARGGNGTNGARGTNATHGGNCAYATHTAYYTNAGYGTNGAYAGYGAY ACNGGNMGNAARATHGAYTAYGTNYTNAAYGARAARGTNTGYAARAAYGAYAAYTCNGTN ACNTTYATHAGYAAYAGYTTYCAYGCNCARCCNGCNGARAARCCNAARCCNAARGTNAAY AAYTCNGARAAYMGNAAYGARGAYTCNGGNGGNGGN------GAYGAYTCNGGNCARTCN ATHCCNAGYAGYACNAAYGTNGGNACNYTNGGNTCN---------------TCNCARGAY GGNTCNGCNTCN------AAYAARMGNCCNMGNTCNCCNTTYCARMGNMGNATGGGNATG GGNMGNGGNGGNTCNGGNGGNCCNGCN---TCNCCNMGNTAYCARGARTCNGGNGGNCCN GCNMGNTCNGGNMGNTCNGAYATHCCNTCNAAYAAYATGAAY---AGY---GGNGARGAY TAYGAYAGYTCN------TTYCAYGGNGGNGAYGAYGAYCARAAYTAYTCNTCNAAYTAY ------CCNAGYCARGAYTCNAAYTCNGARGTNGAYCARAARCCNGTNATHGAYCCNGAY ATHAGYATHGTNAARGARGARTAYATGGCNGGNCARCARAGYGGNGCNTCNTAYTCNGGN AGYAGYCAYCCNTCNGGNCCNGGNMGNGGNCCNAAYCARGCNCCNCARTCNCCNTAYCCN ---ATGATGCAYCARAAY------------------------TCNCCNAGYTAYTCNACN GGNGAYTAYTCNGGNTCNTCNATHGARCCNMGNGAYCCNTCNGARYTNACNCCNGCNCAR MGNGARGARYTNGARATGTAYTAYMGNAARGGNACNGAYCARCAYYTNACNTTYYTNMGN AAYATGMGNGARGCNCAYGCNATGTAYCCNTTYACNGGNAARMGNGAYAARGARYTNTTY GAYAARGCNYTNGCNGARYTNTTYCARMGNYTNCCNGTNYTNMGNGCNGCNMGNTAYTTY YTNAARAGYACNYTNTGYMGNMGNGCNCARACNAARTGYCARTTYAARTCNCCNGGNCAR MGNYTNTTYGCNTGYTAYAAYGAYGGNATHATHAAYYTNYTNGARAARTTYTTYGAYATG AAYAARAARCARTGYAARGAYGCNYTNGAYGTNTAYAARMGNTTYYTNGTNMGNATGGAY AARGTNTCNGARTTYYTNAARGTNGCNGARAAYATGGGNATHGAYAARGGNGAYATHCCN GAYYTNGCNAARGCNCCNGCNAGYYTNYTNGAYGCNYTNGARCARCAYYTNGCNTCNYTN GARGGNAARAARTCNACNACNCCNACNAGYTCNGCNAARCCNTCNGGNTTYACNACNGCN YTNAAYAAYATGTCNAGYAAYACNTTYACNGTNAGYGARGCNGARAARAARMGNATHYTN GAYGARGARAAYCARCARYTNCARMGNCAYAARGTNCARACNTAYGTNCCNTGGAAYGTN CAYGARYTNGCNCCNGGNAARTTYAARTGGGAYGGNATHTCNGAYYTNGARMGNTTYYTN ACNYTNGCNAARGARGARGAYYTNGTNGTNYTNYTNMGNATGGGNCCNTAYATHTGYGGN GARTGGGARTTYGGNGGNTTYCCNGCNTGGYTNYTNGARGTNAAYCCNAAYATGGTNYTN MGNACNAGYGAYCCNTCNTAYATGAARTGGGTNACNYTNTGGTAYAARGARYTNYTNCCN MGNATHAARCCNTTYYTNTTYGARAAYGGNGGNCCNGTNGTNATGGCNCARGTNGARAAY GARTAYGGNAGYTAYTTYGCNTGYGAYAARGAYTAYATGYTNCARYTNMGNGAYATHGCN ACNGCNGGNYTNGGNCARAAYGTNGTNYTNTAYACNACNGAYGGNGCNGGNGAYGGNTAY YTNAARTGYGGNAARGTNCARGGNCCNYTNGTNAAYTCNGARTTYTAYACNGGNTGGYTN GAYCAYTGGGGNAAYCCNCAYGCNAARACNAGYATGGTNTCNYTNGCNAARAGYYTNGAY YTNYTNYTNGCNTAYAAYMGNTCNAGYGTNAGYATGTAYATGTTYGTNGGNGGNACNAAY TTYGARTTYATGAAYGGNGCNAAYGARCCNTCNTAYCARCCNGTNCCNACNTCNTAYGAY TAYGARTCNCCNATHTCNGARGCNGGNGAYATHACNCCNAARTAYTAYGCNYTNMGNGAY ATHGTNTCNAARTAYYTNCCNYTNCCNAARACNCCNATHCCNTCNAAYACNACNAARATG AAYTAYGGNGAYYTNCCNATGACNTTYGCNTGYACNATHCARGAYGCNYTNAARTAYYTN ACNCCNGARGGNCCNACNAARTCNAARTAYCCNGTNCCNATGGARAARATHAARTTYTAY AARGGNTTYATHYTNTAYMGNCAYGTNYTNAARACNAAYTAYACNCARCCNACNACNYTN ATGACNYTNGGNGTNMGNGAYMGNGCNATGGTNATGGTNAAYGGNGTNCCNTTYGGNATH YTNGAYMGNMGNGCNACNACNTCNGTNAAYATHACNGGNACNAARGGNCARAAYGTNGAY GTNYTNGTNGARAAYCARGGNMGNGTNGGNTAYGGNACNGAYATGAAYTTYAAYTCNAAR GGNYTNATHTTYAAYGTNACNYTNGGNGGNGGNATGYTNACNGAYTGGATGATHTAYCCN YTNCAYYTNGAYAAYATHAAYCARTCNATHYTNCAYCARCAYAARGARAARAGYCARYTN MGNGCNCCNATGMGNTCNTCNAAYGGNAARYTNATGACNCCNTCNATHTAYGTNGGNACN ATHMGNATHCCNAARGAYTCNTCNTTYCARGAYACNTTYYTNGAYCCNMGNCCNTTYACN AARGGNCARGCNTTYATHAAYAAYTTYAAYYTNGGNMGNTAYTGGCCNAAYMGNGGNCCN CARGTNMGNYTNTAYGTNCCNAARCCNGTNTTYATGCCNCARTCNTCNACNAAYCAYYTN TAYYTNTTYGARGTNGARAGYGCNCCNTGYAGYTCNCCNYTNAGYTGYAARGTNTCNATG GTNGAYACNCCNTAYYTNGAYGGNCCNAAYGGNCCNGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------MGN AARGAYGCNGARAARMGNTCNCAYGAYAARTCNGGNAARGAYYTNTTYGARCCNGAYGTN AARMGNTCNAARGTNGAYGCNTCNAARGCNAARGAYAARGAY---------GGNAARGAY AARGAYAARGAYMGNGARMGNGTNAARAARGAYAARGARAARAARGARAARGAR------ GARGCNCARMGNCARAARGAYAARTCNGARMGNGARAARAARGARAARGAR---ACNGCN GCNAARGCNGAYAGYGAR---ATGGCNAGYGAYGARGARGARGARYTNTCNCARCARATG GAYGCNGGNGAYTTYGCNMGNGAYYTNGGNATHGCNTGYGTNGTNTGYMGNCARTTYGAY GTNAGYTCNGGNAAYCARYTNGTNGARTGYCARGARTGYCAYAGYYTNTAYCAYCARGAR TGYCAYAARCCNCCNGTNACNGGNCARGAYGTNMGNGAYCCNMGNTTYGTNTGGTAYTGY TCNMGNTGYACNAARGGNTTYAARAARATGATHGCNCARAARCCNGTNAAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNATHATHGCNGGNCCNGAYACNGCNAAYAAR ACNTCNYTNGTNTTYCARGCNGCNGTNTGYGCNGCNACNAAYGGNTCNAAYGTNGTNCAY ATHTGYACNCAYCCNATHTCNAARYTNCCNTCNCCNGTNCAYGGNATGCCNAGYCCNCAR GCNTCNGTNATGMGNAAYGTNGAYTTYYTNTAYTTYGARGARACNACNGARYTNATHGCN TAYTTYGCNGGNATHCAYATGAARAARAARYTNCCNMGNTAYATHATHGTNGARGAYATH YTNTCNTAYGCNTCNCARAARCARGAYAARCCNGTNGARMGNACNYTNGCNAARYTNYTN GCNYTNATHTCNGAYGCNMGNTCNTGGATHTCNGCNCAYAGYGARAGYAAYCARTGYAGY GTNYTNYTNACNGCNCCNTCNMGNYTNAARTCNATGCARAAYATHYTNMGNCARTTYAAR TAYGARTTYGCNGTNTAYGARGGNGCNTCNAARGAYCAYGTNTTYTCNGCNYTNTCNTTY ACNAGYTCNGARGCNCAYATHTCNATHACNTTYCARAAYCAYAARGAYTGYYTNATHYTN GARGAYGTN---------------------------------YTNATHCARATHAARACN GCNGAYGARAARGARGTNCARMGNMGNATHGAYTCNTTYATHMGNAAYAARMGNAAYGAR GTNGAYGARMGNAAYATHMGNGARTTYATHTCNCCNTTYGGNTCNGAYTCNGAYTAYAGY TGYGCNMGNGTNGARGCNGTNTAYATHCAYMGNGARGGNGTNAARAGYCAYATHAAYYTN AARACNGTNGAYAAYGCNTAYGGNCCNCARACNMGNYTNMGNGARGAYAAYAAYGARGAR ATHTCNTCNTGGATGAARTCNGCNGAYATGCARMGNGCNGARGCNGTNGARGARMGNYTN YTNAAYATGGARATGCAYYTNAAYATHTCNGAYAARGTNGGNGAYGTNTAYAARMGNATH AARGCNYTNGARGARMGNATHAGYTTYYTNGARGGNGTNTCNCCNGARTAYTTYYTNAAY GGNATHCCNCARAAYMGNAAYAGYAARCCNACNCARCARMGNCARGAR---------ATH GTNCARACNAARCARGCNACNTCNGARATHTCNGGNCAYACNACNAAYYTNGTNGTNAAY AARTTYGARGAYCAYYTNTTYATHATHGCNACNCARTAYGARAARYTNGGNACNGTNGTN GARGTNTCNMGNGAYGTNYTNAGYGAYGARGTNCARGGNCAYATHCCNGTNTTYTCNACN CAYGTNYTNYTNGGNAARGAYGARCCNYTNACNCAYGTNATGGCNAARACNATHGTNACN TCNYTNAAYCCNCCNATGCCNGTNATHYTNAGYYTNGCNYTNAARGTNACNACNATHGAR GCNGTNCARGCNATHACNGARYTNATHAARACNTGYYTNATGGCNACNAAYATHCAYTTY GARGCNMGNMGNMGNCARATGGTNYTNGAYMGNGCNTGYCARGTNMGNAARCARMGNGCN YTNGCNCARGARTCNGCNCCNGGNCCNGCNATHAARGARGTNGCNMGN------CCNGAR ACNATHATGTGYACNGAYCARGGNCARTTYTAYCARACNMGNNNNAGYATHCAYGTNTGG ACNGGNACNGARMGNAAYMGNMGNTCNTAYGAYMGNAGYMGNGARGGNCCNATHYTNGGN GGNTCNCARMGNCARYTNGARMGNGARATGAAYTTYMGNCARAAYAGYYTNAGY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------ATGCCNAAR TTYTAYGARGAYATHGARGARAARAAYCCNAARCCNAARYTNGCNTGYGARGGNATHMGN GAYGAYYTNYTNGARTGYYTNYTNAARAGYGAYTGYTGYAARAARGAYAARAAYACNCCN MGNGARTGYATG---------AGYAARATHGGNGAYCCNTCNGTNCCNGAYGARTGYCAY AARYTNMGNGTNGCNTTYTTYGAYTGYMGNMGNTCNATGYTNGAYATGMGNACNMGNTTY MGNGGNMGNAARGARAARGTNCARYTNYTNGAYGARACNGAYGARYTNGARGARATHTTY GARMGNAGYATHTAYACNTTYYTNTTYATHACNCARTCNTTYYTNGARGARCARTGGACN YTNATGTTYTCNCAYGCNTGYYTNAARCARATGYTNTCNGAYCCNTCNAGYYTNATHCCN GTNCAYGCNAAYCCNAAYAAYAARMGNGAYTAYMGNATGCCNYTNYTNYTN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GARGAYAARTCNMGNAARAAYGCNGTNCARGCNAARATHAAYMGNGARAARAARAARGCN TAYATHAARAGYYTNGARGAYGARATHAARTCNYTNAARAGYGAYAAYTGYACNYTNAAR TCNGARAAYACNYTNATGAARACNAGYACNTCNGARYTNGARGARGARGTNGCNTAYYTN AARTCNGTNYTNATHAAYTCNAGYGCNYTNGCNGGNYTNYTNAARAAYATHTCNAAYGTN AARGARGTNAARYTNTCNGCNACNATHATHGGNMGNAARMGNTCNGCNGGNGARGAYGAY ------AGYTAYAAYATGGTNGGNAGYTCNTCNGCNAARMGNGCNMGNAGYATHAAYGAR AAYYTNAARAARGCNGGNGTNTGYYTNCAYGTNAAYGAYGGNTCNGCNTGYATHGARTTY TGYGCNCAYTGYTCNAARYTNGCNCARAARTCN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARGGNATHGTNGARMGNGTNAARGARATGGGNGAR ATGTTYTGYAAYGCNTTYGARCARCCNTCNGARGGNCAYCCNGGNTCNCAYATHGAYTTY GCNAARAARMGNYTNCARYTNGGNGARAGYYTNTAYTAYAARATHYTNGARAAYATHATG GTNAARGARAARGARMGNGCNAARGAYAARGAYYTNGAYTTYTCNAGYYTNYTNGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------GGNACNAGYTAYGGN GCNAGYGTNGGNCAYAGYTGGTCNCAYAAYGAYGGNAGYAARACNACNYTNTCNGGNAAY GTNAAYCAYAGYCCNTAYGGNGGNACNAGYGCNGGNATHTCNATHTCNCAYTCNTTYGGN MGNGARATGGARGAR---AAYATHTTYGTNGCNGTNCAYTCNGGNGCNGGNAAYCAYTCN CARGARAAYGARAAYCAYAAYAARTAYATHTGYAARATGGCNTGYCARCARGCNATGGAR YTNYTNAARTCNAAYGGNTCNGCNYTNGAYGCNGTNACNGCNGCNGTNACNAGYYTNGAR GAYGAYGARGGNACNAAYGCNGGNTAYGGNTCNAAYYTNAAYGTNCARGGNAAYGCNGAR TGYGARGCNTGYGTNATGGAYGGNAARTCNYTNTAYTTYGGNGCNGTNGGNGCNYTNTCN GGNGTNAARAAYCCNGTNAARATHGCNGGNYTNYTNGTNAARGARCARACNGARGGNCCN YTNCCNTTYGGNMGNGTNMGNCCNAGYGTNYTNGTNGGNAARGGNGCNMGNACNTTYTGY ACNGARCAYGGNATHGAYGTNAAYCAYAAYATGATHTCNAARTCNTCNTTYAARATHTAY AAYMGNTAYAARMGNAARTGY--------------------------------------- ---YTNACNGAYTCNAAYAAYAGYMGNAARMGNMGNAARGTNGAYCAYAARGARGARYTN ACNACNYTNAARGAYGCNAARACNGTNCAYCAYTTYCCNTCNGARAGY------------ ---ATGCARGAYACNGTNGGNGCNATHTGYATHGAYCAYGARGGNAAYGTNGCNTCNGCN TCNTCNAGYGGNGGNATHTGGYTNAARCAYCCNGGNMGNYTNGGNCCNATHTCNATGTAY GGNGCNGGNTGYTGGGCNCARAARAGYAARYTNAAYGGNAARACNGGNGTNGCNGTNGTN GCNTCNGGNTGYGGNGARCAYATGATGCARACNATHYTNGCNAARACNTGYGCNGAYGGN ATHMGNTCNTCNGARAAYYTNACNCARTCNYTNCCNCARGTNTTYAARAARGAYTTYATG GARTCNGARTTYYTNTCNACNAARTCNGARAARYTNGCNGGNGCNYTNGCNYTNAARYTN GTNGARTCNGAYGAYATHMGNGARGTNGARYTNTGYTGGATHCAYTCNACNGCNAGYTTY TGYTTYGGNTTYATGGGNGGNGAYCARAARTAYCCNAARGCNGTNATGTCNMGNYTNGAR GAYACNAGYACNCCNGGNCAYTCNTTYACNATGGGNGGNCAYYTNATHTGYYTN------ ---------------------------------------------GARCCNGCNGTNATG AGYYTNGAYGTNCCNATHGGNGCNGTNCARGTNACNTCNAARTAYGGNCARCARTAYCAR TGYAGYTTYCCNGAYCAYGCNGARGAYGARAARAARAARGARGARGARGARAARGCNGCN GTNGARACNGGNATHATHGARATGYTNAARCCNATGCARACNATHGAYTGYYTNATHAAR ACNAARGAYTGGTGGACNTAYGARTTYTGYTTYGGNAARTCNYTNMGNCARTAYCAYATG GARGAYGGNGARATHAARAGYAAYATHATHCAYYTNGGNYTNTAYGARAGYGAYTTYGAY TGGAGYAAYGCNAGYGCNAARGARGARMGNYTNMGNTCN------ACNYTNGCNAGYTAY CAYTCNCARATHTAYAGYAARGGNGAYATHTGYGAYYTNACNGGNAARCCNMGNAARGTN GARGCNMGNTTYATGTGYGARGARAAYTCNGARGAYTAYYTNTCNMGNATHGARGARTCN GARACNTGYGTNTAYACNGTNACNGTNATGACNTCNMGNATH------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARCCNCAYCCNYTNYTNCARACNGTNGTNAGYGGNGCNAGYGGNATHYTNTTY GGNATHGCNYTNGARAARGGNMGNGTNTTYGARCCNCARGTNATHATHGAYCARATGYTN TTYMGNMGNTTYGTNATGYTNAARATGTTYYTNTCNGCNTCNYTNGTNGGNATGGTNAGY ATHTCNTTYYTNAARYTNATHCCNCARACNGARMGNMGNATGGARATGGCNYTNCARAAY TTYACNCAYTGYYTNCARTTYAARAGYGTNTCNGGNGTNGCNGTNGGNGCNGCNATHYTN GGNACNGGNATGGCNATHGCNGGNGCNTGYCCNGGNACNGTNYTNGTNCARYTNGGNGCN YTNATHCCNAAYGCNTGGGCNACNGTNGCNGGNGGNYTNTGYGGNGCNGTNYTNTAYTCN YTNACNGARCCNTAYYTNGAYAAYGTNTTYMGNMGNMGNACNAARTAYAARGARTAYTAY YTNGAYMGNTAYYTNCAYYTNCCNTAYATGACNYTNGCNATHCCNATGGCNTCNGCNATG GCNGCNGTNGTNYTNGGNYTNGARTTYCAYTTYCCNTGGTTYACNGARGTNTCNAGYACN YTNGTNACNAARGGNGTNATGAARGCNGGNGCNTGGCCNCCNTTYGTNACNGGNYTNATH ATHGGNACNYTNCARATHCCNATGATHATGGTNAAYMGNGAYACNYTNGGNTCNGCNACN AGYTAYGTNACNATHGCNTCNCARTTYTTYCCNTTYTAYAAR---------GAYAGYCCN GGNGAYAGYTAYATGAARAARTAYMGNTAYGGNATGGAYAAYTGGTGGCARGTNGTNTAY GTNGCNGGNGCNGTNGCNGGNGCNTTYATHTCNTCNTCNAGYTCNCARAGYATHGGNACN GTNGARGGNYTNCCNTGGCARAARGGNTTYGGNGGNGGNYTNYTNATHATHTTYGGNTCN MGNYTNGCNGCNGGNTGYACNAGYGGNCAYGGNYTNTCNGGNATGGGNYTNYTNGCNYTN YTNTCNTTYGTNGCNGTNCCNGCNATGTTY------------------------------ ------------------------YTNAARGARGARYTNGARAARYTNMGNATHGARGTN GGNGAYATHAARGCNGCNGTNGCNYTNACNGARTGYGGNMGNCARGAYGAYGTNTCNGAR ATGCARMGNAARTAYCARGARGARATHTCNTCNYTNCARCAYATHATGGAYGCNTCNATH GAYGARGCNTCNMGNAAYACNGCNGARAARTAYGARGARGAYMGNATHCAYYTNYTNAAR GCNAAYGARGCNYTNGARGCNGARGTNGARGARYTNAARAGYAARYTNTCNCARGARMGN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGTTYMGNCCNGAYAARGAYYTNCCNTCNGGNATGYTNCCNTCN CARCCNACNTCNCARATHTCNGGNTTYAAYGGNGGNACNAGYTAYTAYGGNCARGGNAAY YTNTCNYTNCARCAYMGNGCNATHGGNGCNAAYCAYTTYMGNGGNAGYAAYAAYACNGGN CAYATHACNCCNACNAGYATHAAYCCNGGNTTYCCNYTNGGNYTNCARCAR---CARCAR CARCCNTCNCARCARCARCARCAYTCNCCNAAYAAYYTNGCNGCNATHGGNTCNMGNAAY GTNYTNAGYGTNCARAAYCARGGNGGNCCNCARGGNATGGTNAAYATGCARAARMGNCCN TTYAGYTCNGCNGGNCCNATGCCNAAYTTYGCNTCNAGYTAYGGNTTYGGNGGNACNGGN TCNATHGAYTCNCAYCCNACNATHGAYYTNTCNGAYTTYCCNACNYTNAGYAGYMGNGCN TCNGCNACNCCNAAYCCNCARCCNACNACNMGNAAYTAYGTNGGNATGGTNAGYAARCCN CCNCARGAYACNGCNCCNGARTTYAAYATHTCNCARGARGARTTYCCNGCNYTNCCNGGN ---------------------------ATGTCNGAYTAYMGNGGNTCNMGNGGNMGNAGY AGYMGNGGNMGNTTYGGNCCNCCNMGNGGNGGNGGNTTYMGN---GGNMGNGGNGGNTAY ATGGAYMGNGARGARMGNGGNGGNMGNGGNGGNTTYMGNGGNMGNGGNGGNTTYTCNMGN GGNMGNGGNGGNCCNCCNMGNAGYMGNGAYGAYYTNTCNCCNCCNMGN------ATHTCN MGNAGYTAYGARTCNTCNGAYMGNGGNMGNGGNCCNCCNGCNTCNMGNCAY---GAYMGN TTYGARGAYAGYTTYGARMGNGGN------CCNGCNMGNTCNAARGAYYTNTAYTCNTCN CCNCCNMGNGARTCNAGYMGNAAYTTYGAYMGNCAYTCNCCNCCN------CCNMGNMGN GARMGNGAYTAYCCNCCNMGNAGYAGYGAYCAYATHAGYTCNGGNMGNGGNGAYTAYYTN TCNCCNMGNAGYTAYAGYCCNCCNMGNGAYTCNGGNTAY---AGYTCNTAYAARGAYTCN TAYAGYTCNGGNCCNMGNGARGARMGNMGNCCNGTNMGNGAYTAYGCNCCNMGN------ ------------ACNAGYGAYTAY---GARMGNMGNGARTTYMGNGAYGGNCCNAGY--- MGNGARTAYACNTCNTCNMGNGAYTAYCCNCCN---------TCNMGNAGYGAYTTYMGN GGNTCNMGNAAYGGNGGNGAYTTYMGNGGN------------GCNMGNAAYGGNAGYGGN GAYTTYATGAGYGGNMGNGAYTTY------MGNTCNGAYTTYMGNGAYGCNCCN---MGN AGYGAYMGNTTYACNGGNAGYGGNMGNTCNTCNMGNYTNGAYGAYMGNGGNCCN------ ---CCNMGNGARTAYAGYGGNMGNGGN---------------MGNGGNYTNMGN---GAY GAYMGNGGNAGYMGN---GGNGGNTTYATGAAYGGNGGNGGN------TCNMGNGGNGGN CCNMGNGGNMGNGGNMGNGAYTTYTCNGGNAGYMGNTCNGAYMGNMGNTCNYTNAGYMGN GARGGNGCNGGNGGNAARMGNCCNMGNYTNGAYGCNGAYGAYTAYMGNMGNGCNGTNTCN ATHATHGARACNAGYATHGGNAARGAYGCNGAYTGYGARMGNGTNTTYAARMGNTTYACN TTYAARTGYYTNCARATHATHGTNCARTCNMGNATHGARCCNYTNCARGGNMGNGAY--- ---ACNTCNAGYGAYTAYTTYAGYATHAAYYTNCCNGARTGYCCNATHGTNGAYGARCAR ATHMGNCARACNYTNGAYGGNATHAARTCNTAYCCNATHMGNGAYMGNTCNATHTGYGTN GARGTNGCNYTNMGNACNAAYGAYGGNGAYCAYATGTTYYTNGARACNTGGGAYYTNAGY TTYAAYYTNAGYAGYYTNGAYATGTCNGCNAGYAARATHCARCAYATHTTYACNMGNATG GGNYTNACNYTNAARTCNYTNYTNTCNGCNACNMGNGCNGTNCCNGCNTAYMGNYTNGCN MGNAAYCARGGNGAYAARGGNGGNGGNTAYAARYTNAAYTAYMGNTTYTAYCARGGNCCN CCNAARACNCAYYTNYTNGGNGARGAYTTYAARACNGTNMGNGCNGGNGCNYTNCCNTCN GCNTAYGGNYTNYTNAGYATHAAYGTNGCNTAYMGNACNAARYTNYTNYTNTCNCCNGAY ATGGCNTCNTCNTCNTCNAGYGTNATGCARGTNACNGAYGAYTAYTTYATGAARGARCAY GARAGYAARCARCAYGCNCARATGAAYTCNGAYCCNAARCCNTGY--------------- ---CAYTCNTCNYTNTCN------------------AGYCCNGARTCNYTNGCNGCNGCN CCNTAYCAYTAYTCNYTNTCNCCNTCNTCNGTNGGNACNGAY---GAYTAYYTNATGTCN AARATGTGYGTNGARAAYCAY------GGNTGGCCNYTNGCNAGYYTNYTNAAYATGGAY GARYTNCCNGARCCNACNGTNGGNGCNTTYTCNACNCARMGNCCNAAYGTNYTNAARGTN GARGARMGNGAYYTNCCNTTYGARGGNYTNATGAARMGNAGYATGATGGCNMGNYTNGAR CARAARCARAARCARGARATGAARGAYAARGGNGTNGAY------AGYGGNTTYGGNMGN TCNAAYGARATGAARAARATHGGN------GCNAAYGAYGAYGARAARGARAAYGTNGGN GTNYTNAAYACNTTYTTYAGYAAYYTNCCNYTNGARGARGAYTTYGTNATHGTNGAYCCN CCNTTYGCNTGYGAYGAYGAYCCNMGNGAYGTNAARTCNTTYYTNGGNAGYATHTTYMGN GCNCCNCAYYTNTAYGAYGTNCCNGAYACNMGNYTNAGYGTNGAYGAYTAYYTNAAYGAY GTNGAYATGATGGTNTCNCARYTNGARGARGAYATGCCNGTNYTNGAYGARTTYTGYCAR TCNGTNATHAAYTTYCAYAGYACNGARGAYGARGAYGARATHGARYTNYTNTGGGARGAY AARGCNTCNAAYCARYTNYTNGCNAGYGTNMGNYTNTAYTTYMGNCCNGARCAYACNCCN GAYGGNMGNCARGARGAYGCNGGNGARCAYGARATHCAYGTNYTNGGNGARMGNYTNGTN YTNMGNYTNGAYGAYYTNYTNCCNYTNATGCARGARGGNTTYGGNTGGGAYTAYGGNTAY CAYGCN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARAGYACNGARYTNTCNYTNGARTGYYTNAAYTGY YTNAARAARTTYTGGTCNYTNTGYTCNAGYCARCARAAYACNGTNTGYTCNTCNCARYTN TTYGGNAARTGGGAYCCNTCNYTNGTNGARTCNATHTCNCCNYTNGCNTCNATHTTYACN GAYYTNTCNATHACNGCNTAYMGNGAYAARGARAAYMGNTCNATH------TGGTCNAAR MGNYTNTAYAGYTGGYTNAGYTTYGAYYTNCCNGAYMGNGCNGTNAARGTNGCNYTNYTN GARGTNACNGGNCAYTGYAARGARGGNGCNGAYATHGTNGCNCCNYTNYTNAGYGAYATG YTNACNMGNCCNTTYGAYGARGGNTCNAAYGCNGARTAYYTNYTNCAYTTYYTNYTNYTN AARAARTGGCARGGNYTNAARGGNGTNGCNAGY---YTNGTNGARMGNTCNAARTCNATG AARGCNCCNCCNTCNTTYYTNGAYTGGYTNGARACNTAYTGGMGNGARGCNGARGGNTAY ATHCCNACNGAYAARAGYYTNAARGGNTCNMGNGTNAGYGARTTYYTNYTNGAYYTNGAY TCNGAYGARGTNYTNGARCCNYTNACNGAYGCNYTNCARGARGGNGGNAARGGNGTNACN GAYGGNGARGCNGAYATGGARACNTCNGAYACNCCNYTNTTYGTNGTNGAYAARAARGGN CCNACNGAYTTYACNCCNTTYTTYCARGGNCARAAYCCNACNAGYATHCCNAAYATHACN TGYAARACNAGYAGYCCNCAYTCNGCNACNACNCCNCARMGNCCNAAYGCNAGYCCNTCN GGNAAYAARTCNYTNTCNGCNACNGGNAGYCCNGCNGARCARMGNMGNCCNGTNAARGTN ATHAAYATHCCNGCNGGNTCNYTNTCNGGNGGNTCNGTNTCNCCNGCNGGNACNCCNYTN AAYTCNMGNCAYTTYMGNATGCAYTTYGGNGAYACNGGNGGNACNTGYACNGTNCARAAR AAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------ATGGARAAYYTNAARYTNAGYGAYCARGARYTNMGNTTYTAYGCN GARYTNTTYGCNGCNTGYGAYTCNGARAAYAGYGGNMGNGTNCCNGGNGTNMGNGCNTCN GARYTNTTYYTNACNTCNGGNYTNCAYAAYGARATHYTNTTYCARATHGCNGARATGTGY GGNGCNAARMGNYTNGGNCAYTTYGGNMGNAGYCARTTYTAYATHGCN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARTTYACNGAYGAYGARATH MGNGARGARYTNGCNCARYTNGGNTAYCAYAAYGTNCCNGARGAYAARYTNGARGAYTTY AARMGNGAYYTNATGAARYTNATHTCNACNGARMGNAGYAARACNAAYTCNYTNAAYAGY AGY---------------MGNACNACNGARCCNGAYATHMGNGAYAARMGNTAYCARCCN AARYTNACNGAYTAYACNGCNGAYTTYAGYAAYCAYGGNAGYCARTGGATH---GGNAAY MGNTTYAAYGARGAYTGGCAYTAYCAYGGNGARAARGARAGYACN--------------- ------------------------CARMGNCCNTGY---------------------ACN GCNCCNGARATGMGNGGNMGNCARMGNAGYGGNAGYTAYTCNGGNTTYGARYTNCARCCN TCN---ACNTCNGGNAARAAYYTNGGNMGNAAYCARAAYTTYMGNGAYGAYGTNTCNGAR ACNGAYTCNGARTGYAARATGATGAARMGNAARACNTCNMGNAARACNGCNGAYGGNTGY CARYTNATHGAYGARTCNTTYACNGAYAGYGAYTCNGGNGTNATGGARATHTAYGARMGN ATHAARAAYYTNGCNATGMGNGARTGYGARTGYGGNAARAAYMGNCCNAARTCNGGNGAY GTNGARCCNCCNTAYMGNATHAARGGN---AARAAYAARTAYCCNTCNGTNATHAARAAR GCNAARCCNCCNCAYACNMGNAAYYTNGTNMGNACNAAYTGYTAYGARMGNCAYAAYATG TAYAARGARATGTGGAARACNMGNCCNCCNATHGGNGARGAYGAYCAYGTNGGNATHMGN AARGCNATHCARGCNAARYTNYTNCAYTTYAAYGARATHAARYTNAARCARAARGTNTAY GTNCCNAAYYTNTAYGTNCCNCCNCAYGARAARGCNMGNAAYGGNGTNMGNTGGAARGTN MGNCARGCNTTYGARAARTAYGARYTNCCNGARCAYGGNTTYTAYCAYGARACNYTNAAR AARGARAAYGARGGNYTNYTNTTYAARACNAAYAARYTNCAYGTNGCNAAYAARGARTGG AARGAYMGNTGGGARGCNYTNAARAARCARAARGARGAYGARAAYYTNGARYTNMGNGCN CARGTNCARMGNYTNATGGAYATGAAYGGNAARATGAARMGNGARACNGARCCNGTNATH GCNTCNYTNAARAARGARYTNTTYGARGCNAAYGCNTCNAARAARGARGCNGARAARTCN TAYGCNGTNYTNCAYAGYGGNMGNCARCARGARAARCARYTNYTNGARAARYTNAARCAR GAYTTYGGNAAYYTNCAYCARGARAARMGNACNYTNGARATHCARYTNGARACNATGAAR GGNAAY---TCNMGNACNCCNGTNGARMGNTCNAARACNAAYACNGARYTNGARACNGAR YTNGGNGTNGTNAARMGNCARATGGCNYTNTAYATHGAYGAYTTYAAYAARGARCAYCAR GARMGNYTNGTNATHGAR---------GARMGNYTNCAYAARGARAARGAY---GCNAAY AARAGYYTNGAYAAYAARYTNAARAARACNCAYGCNYTNYTNAARTCNMGNGAYGARGAY YTNMGNMGNAARACNAARCARGTNTCNGAYYTNCARTTYCARAAYGAYGAYYTNAARATH GARATHGARCARMGNMGNGCNTCNATHTAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ACNGTNMGNGCNCAYATGGTNTCNATG YTNTCNGARYTNGGNAARGAYGAYGARAAYTCNGCNYTNGCNGGNYTNATGGCNTGGATG CARGCNAAYTAYGTNGAYMGNGGNGARYTNGAYMGNAARYTNTCNYTNGTNGCNGCNGAY ATHACNGCNAARATGCARACNYTNGTNGAYGARCAR------CARMGNCARGCNGCNGCN ---------------------GCNGCNGCNGTNAARTCNATHGTNGARGARGCNYTNGTN CARTTYAGYGCNGAYMGNGTNGGNYTNCCNGAYTTYGCNYTNGARTCNGCNGGNGGNAGY GTNYTNAGYACNMGNTGYTCNGARACNTAYTAYMGNAARACNGCNYTNGTNAGYGTNTTY GGNATHCCNYTNTAYTAYACNTCNAAYTCNCCNMGNACNGTNATHCARCCNAAYGTNCAY CCNGGNGARTGYTGGGCNTTYMGNGGNAGYTCNGGNTAYGTNYTNATHCARYTNTCNCAR CCNATHCARCCNACNGGNTTYACNYTNGARCAYATHCCNMGNAGYYTNTCNCCNTCNGGN GAYATHGAYAGYGCNCCNAARGGNTTYACNATHCAYGGNYTNGTNTCNGAYGGNGAYACN GARGGNGTNAAYYTNGGNAAYTAYACNTAYYTNGAYAAYGGNAARCCNATHCARCAYTTY CCNGTNCARAAYMGNCAYCCNGGNGTNTTYCARTAYGTNGARYTNMGNGTNYTNAGYAAY CAYGGNAAYCCNGARTAYAGYTGYATHTAYMGNTTYMGNGTNCAYGGNYTN--------- GAYGARTAYAARTGYCCNTCNAGYYTNACNCAYAARTTYTCNCARYTNGTNATHYTNGAY CARCARATHAAYAARTCNGAYTAYCAYYTNCCNYTNGGNAAYCCNGTNACNACNTCNYTN ATHGAYCCNTCNCAYCAYCCN------GCNGAYGTNGTNGAYCCNYTNCCN--------- YTNCARCAYACNCCNGCNAARGARGCNAARGARATHYTNAARATHMGNCAYAARAARATG AARAARCAYAARYTNAARAARYTNMGNAARMGNATGTAYTTYYTNTGGMGNAARCARAAR ATGATHMGNMGNTCNAARMGNGAYGTNATHTAYTGGAARGARATHGARGAYATHAARAAR GARGGNGARGAYTTYGAYGCNGARTCNTTYGTNAARGARGARYTNCARAARGCNMGNMGN GGNGGNTAYTAYATGAAYGTNTTYGCNTCNAARGTN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------MGNYTNATHCAYTCNGTN YTNAAYTGYYTNAARTCNAARMGNGARYTNGTNGAYAAYGGNGARGGNGTNAAYYTNATH TCNYTNATGGTNTCNATGGAYTGYGAYYTNAAYGTNAARGAYTAYAAYCAYAARTCNCCN YTNATGGTNGCNGCNGARYTNGCNCAYGCNCCNATHATGAAYYTNATHYTNCCNAGYTGY ATGGAYTGGCARYTNTTYACNCCNYTNCAYATGGCNTGYATGAARMGNTTYAGYAARAGY GTNYTNAGYGGNGGNTGGAAYCARGTNTTYYTNACNYTNCAYMGNGAYACNMGNYTNAAY ATGTAYAARMGNCARGGNGARTCNATHCCNCARYTNACNATHATHATGAARGAYGTNTGY AARCAYTTYGCNTTYGGNGARTAYACNAARGGNATGCCNGARMGNCCNAAYGTNCCNGCN GGNGCNTCN--------------------------------------------------- ---AGYTCNGTNAAYYTNATHTCNAARATHGTNTGYACNGTNAGYTTYTGYTTYTTYGCN ATHAARTAYCAYGAYCARTCNYTNTTY---CARGARAARCCNMGNGCNCARATHGTNATH GTNATHAARTCNATHGCNYTNYTNGCNATHGTNAGYYTNACNTTYCAYTGYGTNGCNGTN YTNTTYGGNGCNCCNYTNTTYGARTCNGTNACNGARACNTTYCAYTTYGCNGTNYTNATG ACNACNYTNACNGCNYTNCCNTGYTGYYTNGCNGCNGGNCCNAARYTNGAYAARTGGATH GAYATHTTYACNCAYGAR---MGNGAYGCNGGNYTNGARACNATHGTNTAYYTNGCNAGY YTNGGNGCNYTNYTNGGNGGNTGGYTNGGNGCNGTNCCNATHCCNYTNGAYTGGGAYMGN CCNTGGCARAAYTGGCCNATHACNTGYTCNGTNGGNTGYATHTCNGGNTAYTCNGTNGGN YTNTTYYTNGCNTCNYTNTAYYTNCCNCAYCARTAYAARYTNYTNYTNAARCCNAARYTN ATGYTNGTNGTNCCNGGNAAYCCNGGNGTNCCNACNTTYTAYGARGAYTTYATGMGNGAR YTNTAYAAYCARTCNGGNGGNCARATHCCNGTNTGGGCNATHGGNCAYGCNGGNCAYACN AARCCNCCNGAYAGYTCNYTNTCNYTNGGNGAYATHGTNGCNACNGAYCARMGNACNTAY GGNYTNGARGCNCARATHGAYCAYAARGTNGCNTTYATHMGNGARCAYATHCCNCCNGAY GTNAARYTNATHYTNGTNGGNCAYTCNATHGGNTGYTAYATGATHYTNAAYTCNYTNGAR AARYTNGCNCCNGAYTCNGTNCAYMGNTGYTAYYTNYTNTTYCCNACNATHGARMGNATG GCNGTNTCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------AAYCCNAARAARYTNCAYGARGTNACNMGNATHGCNTCNYTN ATHTAYGARMGNGCNTCNGCNACNAAYTGYAAYATHATHGTNGAYGTNGGNTCNGGNYTN GGNTAYYTNGAYCAYGTNYTNCAYCARAARTTYGGNYTNAARGTNYTNGGNATGGARATH GCNCARAGYCAYGCNTCNGCNGCNGARAARMGNGCNTTYMGNCARGGNATHACNTGYGGN GGNGTNGTNCARTCNATHTAYCCNACNYTNACNGGNTGYGARTGYGTNCARAARAGYGAY ATHGTNGTNCAYCARGARGCNATHTGYTGYGTNTGYTGYTGYTAYCAYAARATGGCN--- ---TAY------------------------------------------------------ ------------------------------------------------------------ ------------------------------TCNGARGARAARTTYGCNAARTTYCCNYTN AGYGCNMGNGGNAARTCNYTNTAYACNGARAGYATHCARACNCAYGGNCARCCNTTYATH ACNCCNTTYACNYTNMGNYTNGGNGCNCARGARACNMGNTGYMGNTGGMGNCARCARACN AARAARGAYCAYGARGAYCAYATHCAYCAYGTNGCNTTYMGNGGNYTNYTNAGYYTNACN GAYGARGAYGARCARCARATHMGNCARAARATHMGNAARAGYAARTTYGAYTCNTTYCAR AAYTTYGTNGAYTCNTAYTAY---GGNTCNTCNACNGAYGGNTCNTGYCARGARAARMGN TGYMGNYTNACNYTNYTNTAYGAYAARTAYAARAARGAYTTYGAYACNATHGARATHYTN ACNYTNYTNCARGTNATHYTNCARCCNGTNATHGARACNYTNATHTAYCARGAYMGNGCN CARTGGYTNCARGARAARGGNCARGAYAAYGTNGAYGTNGTNCCNATHTTYGAYGARYTN ATHTCNCCNMGNAAYYTNGCNATHGTNGCNATHAARAARYTNTGYCARCARTGYGTNCAR AAYGGNGTNTCNAGYYTNAAYGAYGTNGCNCAYAAYTTYTGGGCNCARMGNYTNAAYGTN MGNYTNAARYTNATHACNAARAGYTTYTGYCARAARATHGAYATHYTNTCNGARGTNYTN TCNAARCARTGYAAYGTNGTNATHGCNCARMGNATHMGNMGNACNTAYCARATHATGYTN YTNTAYMGNAAYYTNTAYGGNGARMGNYTNYTNAARGARCAYATHAGYACNCARYTNAAY MGNATHAARAARMGNCCNYTNGCNGCNGCNYTNTCNGCNTGYGTNTTYTGYTGGGAYAAR GARMGNGTNACNGAYGARGARATHAARMGNGCNCARMGNGARGTNGAYGCNGTNCAYAAR YTNTCNAAYGGNCARGAYGCNAARAAYTCN------------------------------ ------------------------------------TCNCARTGGGARCARATHGTNGAY ACNGAYGARTTYAARGTNTGGMGNTGYCARATHGCNAAYTCNCARYTNTAYGARTAYMGN GTNYTNGGNCAYTTYAARGAYATHCCNGCNMGNGCNTTYTAYAAYACNCARGTNGAYGTN GGNTAYTGGAARGAYTGGGAYAARCARACNATHGAYGTNAARGTNGTNGAYAARGAYGAY AARACNGAYTCNGARGTNATHCARTGGYTNTAYAARTTYCCNTAYCCNATGTAYCCNMGN GARTAYYTNTAYGTNMGNMGNTGYGTNGTNGAYAARGGNACNAARACNATGGTNATHACN GCNMGNTCNACNGARCAYCCNGAYTGYCCNATHAAYGAYGCNAAYGTNMGNATHATGACN TAYACNTCNMGNATGGTNATHTCNCCNTTYAARAGYTTYGAYGARAAYGGNTTYACNTAY ATGATGTCNTAYMGNGAYGAYCCNCARACNAAYTTYCCNCCNATGTGYTAYAAYTGGYTN GCNAGYTCNGGNGTNCAYGARTTYYTNGARMGNATGCAYMGNGCNACNYTNAAYAARTAY GTNAARCCNGCN---GAYYTNACNACNAAYGTNAARGARCAYAAYCCN---CCNYTNTAY ACNGGNATGGCNCAYATGYTNYTNMGNYTNAARGARGTNATHCARTGGACNMGNATGACN GCNYTNGARYTNATGTTYCAYYTNATHTCNGTNYTNGTNTTYTCNATHYTNYTNGCNTTY AARGTNGARGARTTYATHACNGCNTCNTGGYTNGTNATHTTYGCNCCNYTNTTYTTYTGY GAYGGNYTNAAYGCNTAYYTNTGYGTNATHATHTTYGTNMGNCARTAYMGNGARTAYGAR YTNAARCARGCNTGYYTNMGNYTNTCNAAYTCNYTNTTYGTNATHGCNYTNATHTTYACN TTYAARYTNYTNYTNTGYCAYAARYTNGCNAAYGGNGGNYTNGCNTGYTCNGARGCNGTN ACNCCNATHTAYATHYTNGCNCARATGTTYATGATHMGNGCNTGYMGNATGCAY------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------ATGGCNGAYAARGTN GARCCNCCNCCNTTYGARAAYGAYGARAGYGARATHAARGARGARGAYGAYATGTTYTCN GAYGCNAARGARAARACNTCNTCNCCNGARACNGCNAGYCCN---GARTCNACNGTNAAY GGNACNGAYGARAAYCCNTTY---GARGARGARGAYGAYGAYGAYGAYATGTTYACNGGN GGNAGYTCNGARATHAARYTNGARTCNGAYGARGARGAR--------------------- ---------------------------------------GARCCNGARACNCCNGARACN ACNGTNGGNGCNTCNGCNGCNAARGARGTNACNCCNGARATHTCNGTNTCNGARGTNATH ACNACNAARACNAARATHGCNGCNCCNTCNYTNAARTCNGAYGARYTNTCN---GARCCN AAYGAYGARAARGAYAARTAYGARYTNGAYATHAARATHACNGARAAYGTNAARATGGGN GAYGGNATGTCNGCNTAYATGGTNTTYAARATHGTNTCNAARACNACNAAYCCNGCNTAY MGNACNCCNGARAAYACNGTNYTNMGNMGNTTYAGYGAYTTYYTNGGNYTNCAYGCNAAR YTNGCNGARAARCAYGTNCCNYTNGGNGTNATHGTNCCNCCNGCNCCNGARAARAGYGTN ATHGGNATGACNAARGTNAARATGTCNAARGARGAYACNGGNAAYATHGAYTTYATHGAY MGNMGNAARGCNGCNYTNGARMGNTAYYTNGTNMGNACNGCNGCNCAYCCNATHYTNGCN GCNGAYCCNGAYTTYATHGARTTYYTNGARAARGAYGGNGAYYTNCCNAARGCNACNGGN ACNTCNGCNYTNAGYGGNGCNGGNYTNATGMGNATGTTYCAYAARGTNGGNGARTCNYTN GARAARATHACNYTNAARGTNGAYGARAGYGAYGARTGGTTYGARGARAARCAYCARCAR ATHGARGCNYTNGAYATHCARYTNMGNAARYTNAAYATHAGYYTNGARACNYTNGCNGCN CAYMGNMGNGARYTNTCNGGNAGYACNGCNGTNTTYGCNAARAGYGCNGCNATGYTNGGN AAYGTNGARGARCAYACNGCNYTNTCNMGNGCNYTNTCNCARYTNGCNGARACNGARGAR AARATHGARYTNGTNCAYAARGAYCARGCNGARGTNGAYTTYTAYGTNATGTCNGARATG ATGAARGAYTAYGTNATGYTNATHGGNGCNGTNAARGAYGTNTTYCAYGARMGNATHAAR TGYTAYAARCARTGGAARGAYGCNGARAGYACNYTNGGNAARAARMGNGARGTNAARGCN AARYTNGARATHCARGGNAARGCNGAYAARYTNTCNCARGCNMGNACNGARATHACNGAR TGGGARCAYAARGTNGARAARGGNGARGARGAYTTYGARAARATHTCNAARAAYATHMGN AARGARGTNGCNMGNTTYGARAARYTNMGNGTNTCNGAYTTYAARGCNAAYGTNATHAAR TAYYTNGARGTNYTNATGGARAAYCARGARAARYTNATHAARTAYTGGGARACNTTYYTN CCNGARGCNAARGCNATH------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---AARGGNAARMGNGTNTTYTTYTTYMGNAAYGGNGAYCCNCAYTAYAARCCNMGNCAR GTNYTNATHAGYAGYMGNACNTAYCARAAYTTYGARAARYTNYTNGTNGAYYTNAGYAGY CARGTNGARACNTCNACNGGNGTNAARTTYATHTTYTCNTGGCCNGARGGNAARGARYTN ACNTCNATHACNCARTTYGAR--------------------------------------- AARTGYCCNCAYGARGGNTGYAAYAARAGYTTYCCNTAYCCNTTYAARYTNAARMGNCAY ATGAARGTNCAYGARGGNTAYAARTGYGAYYTNGARGGNTGYAAYGARGTNYTNTCNACN TGGAGYAARYTNMGNAARCAYAARGTNGARGARCAYTCNCCNGCNYTNGARTGYCAYAAR TGYCARTGYACNTTYAARACNAARMGNATHATGACNGARCAYYTNAARACNCAY---GAR ACNAARGARCCNATHGCNTGYACNTGGGARGGNTGYTCNMGNACNTTYYTNTAYAARAAR AAYYTNACNCARCAYATHMGNGCNTTYCAYGARGGNAARCARGTNTTY---ATHAARAAR CCNAARYTNACNGAYGGNGTNGARAARAARMGNMGNMGNATGCCNAARAARAARACNACN GCNGCNAARYTNAGYGGNYTNGAYGAYMGNCCN---------------GAYGARAAYGAR AARGCNGAYTCNAGYCARGCNGTNAAYGGNGAYGGNGAYMGNCARGTNYTNGCNCCNGCN GARGGNCCNMGNGARGAYYTNATHAAYACNGCNATHAARTTYYTNCARAAYCCNAARGTN ACNGGNAGYCCNYTNCARCARAARAARACNTTYYTNAGYAARAARGGNYTNACNCARGAR GARATHAAYATHGCNGTNGARMGNTCNGGNGTNGGNGAYGTNTCNAGYGTNGGNTTYGGN GCNGGNCARGCNMGNGCNCCNCCNCCNGGNTAYCARCCNGGNATGATGGCNCCNGGNYTN CCNGGNTAYTAYGGNCCN---------CCNATHCCNTCNCARTCNMGNTGGGCNCARYTN MGNGAYYTNACNATGACNTCNTTYGTNGTNGTNAGYGTNTCNTAYGGNATGTAYCARYTN TAYAARATGTAYATHGARCCNYTNYTNMGNGGNAARTCNGCNCARGARAARMGNYTNGAY MGNATHGARTCNGAYATGGAYGTNATHCAYAARTCNGTNACNGARTCNYTNTCNGAYATH AGYAARACNYTNGCNGCNATHCARATGAGYATHACNAAYACNCARCARTCNTCNACNACN YTNAAYATG---GGNMGNGGNATHACNGAYYTNAARTCNGAYATHTCNTCNYTNMGNAGY YTNYTNYTNAAYCARCAY---------------GARAARGARCCNGAYGTNTCNACNAAR ATHGCNMGNTGGTGGMGNCARAARMGNGCNYTNGGNTTYGGNGAYGTNAARYTNAARTGY TGYCCNAARTCNATGYTNTAYCAYATHTCNMGNYTNCCNGAYTGYCARAGYTTYYTNCAR AARGARMGNAARMGNYTNYTNTTY---YTNYTNACNCARCCNTGYGAYAARGCNGAYGTN TGGGCNGCNATHGCNGGNYTNGAYGAYTAYACNGARYTNTTYACNTCNGCNTTYAARTAY ATHTCNCARGCNGTNCARYTNGCNCCNACNTGYCCNGARTAYCARTGGYTNATGGARAAR ATHTCNMGNCARTGYGGNGTNYTNGARGARCARMGNATHGCNYTNAARCAYYTNGARGGN YTNGARMGNTGYTTYCCNAARATHGTNGARGTNYTNMGNGTNGCNAGYCARGAYYTNAGY YTNACNGAYTTYCARGARAARTAYYTNCARGCNAGYMGNCCNGTNATHATHACNGGNGTN GTNGAYGGNATGACNAARATGCCNTTYGAYTTYTCNYTNGTNYTNAARCAYGCNGGNGAY ACNGTNGTNACNACNMGNGARGGNGTNGGNGARTCNYTNTCNTGGGCNMGNYTNGARAAY AARMGNGAYACNACNGTNGCNGARYTNATHCARGGNGTNCARGCNGGNTCNGCNAARGAY TTYYTNTTYGAYTGGAGYYTNCCNYTNCAYTGYCCNMGNYTNGCNCARGARATHTCNYTN CCNTCNTAYTTYAAYAAYAAYTTYYTNYTNCARACNAGYCCNGGNTCNYTNTAYMGNGAY AGYTGGCCNAGYYTNTTYYTNGCNCCNGARGGNGCNACNACNCARYTNCAYGTNGAYGCN TTYCAYTCNCAYTTYTGGATGGCNYTNTTYGARGGNACNAARMGNTGGACNTTYTTYGAY CCNAGYGAYYTNGCNTGYYTNTAYCCNMGNTGGTTYCARTCNATGGAYCCNGTNTTYGAR GTNGAYYTNGGNCARCCNGAYYTNGAYMGNCAYCCNYTNYTNACNYTNACNTGYCCNCAR CARTGYGTNYTNCARCCNGGNGARYTNYTNTTYGTNCCNGCNGGNAGYCCNCAYTTYGTN GARAAYYTNAGYGCNACNYTNGCNATHTCNTCNAAYTAYGTNGAYCARACNAAYTAYTCN AARGTNTGYGARGARYTNAARATHAAYACNYTNCARGAYGARMGNGCNCARGAYYTNYTN CARCARYTNCARGAYCCNGAYTTY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARYTNYTNAARTGGAARATGAGYCCNATHACNCCNATHATHGTNMGN ACNGCNYTNGCNMGNGTNGGNTTYMGNATHTCNAARMGNAAYCAYGAYTGGYTNGGNTGY TTYGGNAARCAYATGAARGCNGCNTGYTTYAARTCNYTNMGNGAYTAYCARAARATHAAY CAYTTYCCNGGNTCNTTYCARATHGGNMGNAARGAYMGNYTNTGGMGNTCNAGYATGCCN GARCCNGCNCCNMGNAARGARCARGTNATGGCNTCN---GARGAYGARGARGARGARGGN GTNTAYGARAAYGARCCNGTNAARMGNGAYGAYGTNTGYMGNGARGCNGAYAAYGTNGAR GAYGTNAAYYTNCCNACNCCNGGNYTNGCNCARAAYYTNYTNGCNAARTTYAARTCNGGN GARGTNCARTCNTCNACNCCNMGNGGNAARMGNGARATHACNCCNCCNAAYCCNACNATG GGNGGNGGNGARTAYGTNTCNGARCCNMGNGCNGTNGTNGARCARTAYCARGGNAARGCN GARTCNGGNGTNTTYGARAGYGARCCNCARTAYGAYCCNGAYGTNATHMGNTCNGGNATH AAYCARCARGARTCNGTNCCNGARAGYGGNTCNGCNAARAARTTYGCNGCNMGNTAYGCN GARYTNCARGARGARAGYAARYTNCCNGTNGTNTCNACNMGNMGN---ATGACNCCNGAY MGNGAYAGYGGNCCNAAYGARTAYGTNTCNGARCCNMGNGGNTTYACNGARAARTAYGAR GGNAARGCNGARTCNGGNGTNTTYGARAGYCARCCNGARTAYATGCCNGAYGTNATHMGN TCNGGNGAYGGNAAR---GARGARATHGTNCCNGARMGNGGNACNGCNAARAAYYTNGCN GARAARTTYMGNCARATHTCNGTNGAYAAYGCNGTNCCNATGGCNAGYMGNGAYAARMGN GARAARACNCCNGAYGTNGTNGCN------------------------------------ ------------GCNAARGTNGARTCNGGNGTNTTYGARAAYACNCCNACNGARGAYCCN GARGTNATHAARTCNGCNAAYGCNGCNCARGARTTYGTNCCNGARMGNGGNTCNGCNAAR AAYGTNATGGCNAARTTYAARGARYTNGARYTNAAYGCNAARTCNCCNCCNYTNTCNCCN GGNMGNMGNAARGARTTYACNCCNCCNMGNGARGAYCARGCNGCNAARGTNTCNGGNGTN TAYGARAGYACNCCNGARTCNAARCCNGAYGTNGTNATGTCNTCNGARTCNCARCARGAR GTNACNCCNGTNGCNGGNACNGCNMGNTCNYTNGCNCARMGNTAYAARGARATHGTNGAR CARAGYAGYTCNCCNGTNTCNTCNAARTCNAARAARGARTTYACNCCNCCNCCNTCNAGY TCNTCNGTNTTYGARAAYCARCCNGAYCARTTYCARGCNGAYTAYAAYMGNCCNGCNGAR TCNGGNATHYTNGARAAYCARCCNAGYGCNCARMGNGARGAYGTNYTNMGNGGNTCNGAR ---AGYACNCCNGGNGTNGARYTNCCNGARGCNGGNACNGCNAARAAYYTNGTNAGYMGN TGGMGNCARATHGARTCNGARAGYGCNAARAAYTCNTCNCCNGGNTCNGCNGGNMGNCAY AARGARTTYACNCCNCCNMGNGAYGARCCN---YTNGTNCARAAYMGNAARTCNCCNMGN ACNCCNAARTCNCCNACNGGNAAYYTNGAYAAYGGNTCNGTNCAYCCNTCNGAYYTNCCN GGNCARTAYCARCCNCARGAYCARGCNMGNGTNTTYGARTCNAAYCCNGARCCNCAYCCN GAYGCNGTNMGNGARTCNGAYACNGAYATHCAYCARGGNATGCCNAARAARAAYACNGCN AARAARATGYTNGCNMGNTTYCARAAYATGCARACNGAYGTNAARAARGARACNCCNAAR CCNATGGTNAARAARTCNMGNGTNGAYCARGTNTAYMGNAGYYTNYTNYTNTCNAARTTY TTYACNAARGGNTGGGGNAARCCNGAYAAYYTNAARMGNATHTTYGARTTYMGNAARATH YTNTCNAAYMGNGARTCNTGYCARGCNYTNGTNGARCARGAYTAYCCNATHTCNATHGAY AARGAYTAYAARGAYGGNGAYTGYMGNATHYTNGARGGNCAYTTYAARTCNCCNTTYGTN GAYCAYYTNCCNGGNATHATGCCNAARGARGTNGARACNGCNAGYTTYCARGCNGTNYTN CCNYTNGARTGGCARCAYCCNAARATGAARCCNATHTGYATHCAYYTNGCNGGNACNGGN GAYCAYTTYTTYTGGMGNMGNMGNYTNTTYACNGCNMGNCCNYTNYTNAARGARGCNGGN ATHGCNTCNATHYTNYTNGARAAYCCNTTYTAYGGNTCNMGNAARCCNAARTCNCARATH MGNTCNAGYYTNCAYAAYGTNAGYGAYYTNTTYGTNATGGGNGGNGCNYTNATHYTNGAR TCNATHGCNYTNYTNMGNTGGTGYGARMGNCARGGNTGGGGNCCNYTNGGNYTNTCNGGN GTNTCNATGGGNGGNCAYATGGCNTCNYTNGCNGCNACNAAYTGGCARAGYCCNATHTCN YTNGTNCCNTGYYTNTCNTGGAGYACNGCNTCNTGYGTNTTYACNCARGGNGTNYTNAGY GGNTCNATHCCNTGGCAYGTNYTNCARGARCARTTYTTYAARAAYAAYYTNTAYCAYGAY GARGTNAGYAARYTNATHGTNTCNCCNGARAARGCNTAYYTNYTNGGNCARCARTTYGTN GTNAAYTTY--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGAAYMGNGGNATHAARACNCCNGTNGTNCAYGCNTCNATHAAYCARAAY GTNMGNGARGGNTCNTTYTGYAARTAYAGYCAYMGNAAYTGYATGCARAAYMGNYTNGAR GGNTAYGARTAYTGYATHMGNCAYATHYTNGARGAYAARACNGCNCCNTTYMGNCARTGY GCNTAYATHACNAARGCNGGNMGNAARTGYCCNGCNGCNGCNCCNAARYTNGARAARAAR GARGGNTAYTGYACNTTYCAYACNAARAARGCNYTNATHGCNMGNCARMGNYTNGCNMGN AARMGNMGNCCNMGNGARACNCCNGAYAGYYTNYTNGARGAYYTNGTNGTNACNACNTCN TCNYTNGAYTCNCARAAYAGYATHGARCAYMGNMGNGGNAARYTNCAYAGYGAYAGYATH GCNACNMGNGCNYTNGARTAYGCNAGYTCNAGYGAYTCNGARGCNGARCCNYTNYTNGTN GARMGNGCNTGGMGNGAYTCNGGNGAYAGYGAYGCNGARAGYATHGAYAGYGAYCARGAR GAYATGYTNAARTAYGCNGGNGTNTAYACNACNGARGARGTNGCNCARATHYTNMGNGAY AARYTNATHMGNYTNCARGCNYTNTAYATHGAYCARTTYAARMGNYTNAARCAYGTNYTN YTNACNAARMGNMGNAARTAYYTNCARTCNCARAARGTNGARAARGARYTNTAYGGNAGY ATHAARMGNTAYAARAARGAYCCNGTNCARAARGARAARTAYGARAARYTNYTNGCNATG AARMGNTAYCAYAARAARTTYGGNGTNGARGCNYTNYTNCARCAYAARTCNACNCARMGN MGNATGAARATHACNGARGGNATGACNCAYAARYTNCCNGTNTCNGTNAARTGYTAYTTY GTNGAYGARGGNYTNMGNTGYAAYCARYTNGTNATHCCNYTNAGYMGNTAYTGYCARAAR CAYATHYTNCAYGAYCARCAYCARATHYTNTAYMGNCCNTGYCCNTTYGCNGAYAGYCAR TGYGGNMGNCCNGTNCCNTCNYTNYTNGGNAGYCARTTYTGYTCNYTNCAYCARGARMGN GARAGYYTNYTNGTNACNATGAARGCNGCNAARGTNGAYMGNCARAARGCNGTNAAYGGN TTYGARCARAARAGYGCNGARTAYGGNAAYATGCARAARGARATGGARAARYTNAARGAR GCNYTNTCNTCNAGYGAYTAYMGNATHAARTGGTTYCARAAYAARYTNAARGARGARYTN GARGCNCAYAARGARACNAARTCNAAYYTNGAYAARACNACNCAYAARYTNAARGARGGN MGNGARGARACNGARGTNATHMGNMGNGARTGYCARTCNATHGTNAARACNTAYCARGAR TCNGARGARATHAARTCNAAYAGYYTNGAYAARGARYTNAARATGAARGARTCNCARTTY AARYTNCAYATGCARCARTGGACNGAYACNGARGARYTNAAYCARMGNACNAARAARGAR YTNGARTCNYTNAARGGNCAYCAYAARGARGCNYTNTTYGARGTNTCNACNYTNAARGAR AARATHCARGGNYTNGARATGTCNMGNTCNGARAARGARTCNTCNATHTCNCARAGYAAY GARYTNYTNAAYAARCARAARACNGAYYTNTCNGARYTNTCNTCNAARYTNAARGARAAR GARAAYYTNGAYGAYGAYTTYAAYMGNGCNCARGARATGATHAARAAYYTNGAYAARGAY ATHTCNGARYTNAARGTNAGYAAYMGNGAYYTNCARAARGAYATGGAYTCNTGYMGNGAR MGNGARTCNAARATGYTNGCNYTNCARTCNGARYTNAGYMGNACNAAYGCNTGYYTNMGN TCNGARAAYACNCAYYTNAGYAAYAARGCNACNAAYYTNATGGCNGAYGTNGARMGNYTN AARATGGARGTNCARGARATGGARACNACNGTNAARCAYYTNACNGAYTCNYTNGARGAR GARAARAARGGNAAYYTNCARACNYTNAGYAARYTNAARGCNTCNGTNGARGARAARACN AARGARAGYGCNGAYTTYAARCARAARTGGGARGAYGARATHGAYAGYAAYAARACNYTN AARMGNMGNCAYGCNAAYAAYGTNAARGAYYTNACNMGNCARYTNCARCARACNAARMGN MGNYTNGARTCNYTNGARGGN------AGYGGNAGYGGNGGNAGYATGGGNTCNMGNACN AAYTCNAAYGGNAGYYTNAAYTCNATGGAY------AAYAGYCAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GAYGCNAAR ACNGAYGCNAAYGARAGYTAYCARACNTTYGTNYTNCAYGAYGARGAYCAYACNYTNGGN AAYGCNYTNAARTAYATHYTNAAYAARAAYCCNGAYGTNACNTTYGTNGGNTAYAGYATH ACNCAYCCNTCNGARAGYAARATHAAYYTNMGNATHCARACNTCNGGNAARCCNGCNYTN CARGTNYTNAARCARGGNTTYAARGAYYTNAAYCARYTNTGYGGNCAYATGYTNACNACN TTYGARTCNTCNACNAARTAYTAYAARGARAAYCAYYTNGAY---ACNTCNGARATGGAY CARACN------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------ATHAARMGNGTNYTNGCNGGNTTYAARMGNGAYGTNGGNACNTCNGGNATHAAR AARYTNTTYCAYGARTTYMGNAGYYTNACNGCNCCNCCNGAYTGGATGMGNGCNGCNMGN TAYCARGTNTCNAARTAYGCNAAYACNTGYTTYGAYTGYMGNAGYGAYTTYGGNATHYTN MGNAARTCNTAYGAYTGYGTNYTNTGYGGNGARYTNTAYTGYGCNAARTGYTCNTCNTGY GAYYTNATHGTNTAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARCAYGAYMGNMGNACNAARCAYCARTCNAARTTYAGYTCNGARCCN GCNGARGGNGARGAYATGYTNTCNYTNTCNMGN---GARACNGAYGGNTGYGGNGCNGAY AARGGNAARGTNCCNTTYCCNYTNGCNATGTGGGAYYTNGARCAYTGYGAYCCNAARAAR TGYACNGGNAARAARYTNAGYMGNATGGGNYTNGTNAARACNYTNMGNYTNAAYCAYMGN TTYGGNGGNYTNATHYTNTCNCCNATGGGNACNAARTGYGTNGCNCCNGAYGAYMGNACN ATHGTNGARGARAGYGGNGCNGCNGTNATHGAYTGYAGYTGGGCNAARYTNCARGAYACN CCNTTYGCNAARATGAARGGNGAYCARYTNMGNYTNYTNCCNTAYYTNATHGCNGCNAAY CCNATHAAYTAYGGNAARCCNTGYAARYTNTCNTGYGTNGARGCNTTYGCNGCNACNYTN TTYATHACNGGNTTYGAYAARGARGCNAAYYTNYTNYTNGARAARTTYAARTGGGGNCCN TCNTTYTAYCCNYTNAAYAARGAYTTYTTYACNAGYTAYAGYGCNTGYCAYACNAGYCAR GARGTNGTNATHGARCARGAYAARATHYTNGCNAGYYTNMGNGARGAYAGYYTNCARGAY AARYTNACNGAYTGGATGACNATGGAYCCNGAYGTNGARATGTGYAAYCCNAAYMGNCCN ------------------------YTNTAYCCNCCNTCNGAYTCNAGYTCNGARGARGAR AGYGARGARGAYGARGARAGYGARGARGAYGARGCN------------------------ ------------------------------------------------------------ ---------------------GAYGTNCARAARAAYGTNAARTGGTTYTGYAGYAAYCAR GARGTNATHGTNGAYGTNYTNATGTGYATHGCNGCNGARGCNGGNGARTGYYTNCCNCCN CARGTNAARCCNYTNATGTCNYTNYTNYTNAAYAARGARAAR---ATGATGGAYGGNTTY GGNTTYGTNTGYCARCAYCCNAARATGYTNGTNAAYCARTGYATGCARAGYAGYYTNCCN CAR---TTYGGNGARTGYTAYAARAAYMGN---------YTNATGAARGTNATGGCNGCN GGNGGNGCNATGTCNGAYCCNAARCARATHYTNTGYAARGCNATHMGNAGYGARGARGCN TGYTTYGTNGARAAYAARGGNACNTGYTCNGAYGAYTTYATHAGYACNYTNGTNGARATG ATHGARAARTTYTTYCCNGTNTCNGAYTGYCCNAARTCN---GARGGNAAYAARCARYTN AAYACNYTNYTNGGNGCNYTNYTNATGMGNGGNCARCCNGGNYTNAARTTYYTNCCN--- ---------------TGGTTYMGNCCNACNTCNYTNAARGARYTNYTNGCNYTNAARTCN CARTTYCCNCARGCNAARYTNATHGGNGGNAAYACNGARATHGGNATHGARACNAARTTY AARAAYCARGTNTAYCCNGTNYTNATHTCNACNTCNACNATHCCNGARYTNTCNAARATH AARYTNYTNGAYGARGGNATHATGTTYGGNGCNTCNGTNACNYTNGCNCARATGGAYTTY GARYTNAARACNYTNATHGARAARGARCCNGARTAYAARACNMGNAARTTYTGYGCNGTN GTNGARATGYTNAARTGGTTYGCNAGYCAYCARATHMGNAAYGTNGCNACNGTNAGYGGN AAYATHGTNACNGCNAGYCCNATHTCNGAYYTNAAYCCNYTNTTYCARGCNGCNGGNTAY GGNYTNTTYYTNYTNGARGARATHAARGTNACNCCNAGYGGNTTYCAYYTNACNCARGGN CCNGGNAAYTAYAARATHCCNTCNTTYGGNAAYATHCCNACNGARTTYAAYGTNTCNYTN YTNCCNGAYAGYGAYAAYCCNTGYACNATHTTYTCNTCNAARGGNATHGGNGARCCNCCN YTNYTNYTNGCN------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TCNGCNACNTCNTCN MGNYTNTCNTGYGCNGARGAYAGYTTYATHGGNGARTTYCCNCCNGAYTCNGTNCCNACN GCNGTNMGNGGNTGGCAYCARGCNGGNGARGGNGTNYTNCARACNCCNTCNCCNAGYGAY AGYGGNGTNGGNGARYTNGARGCNATHYTNMGNGARAARGAYGCNGARATHAAYACNYTN MGNGARGTNATGGAYMGNAAYGARMGNGCNATHYTNCARGTNTAYGARGARMGNAARAAY GCNTGGGCNGTNGAYACNCARGAYYTNAARGARGARTAYGARMGNAARYTNAARATHCAR AGYMGNAARTCNTAYAARACNGARCARGTNYTNTCNYTNCARGTNTAYAARYTNCARCAR GARCARAARGCNGTNGCNGAYGARAARGARTCNYTNGAYGGNGARCARGARGCNYTNAAR ACNCARYTNGARGGNGCNAAYTCNGARATHGCNAGYYTNMGNAARCARYTNGAYGCNMGN TCNMGNTCNGTNGCNGAYGGN------TCNGAYTCNCCNAAYTCNAAYGARGARYTNGCN YTNAARAAYMGNGARGTNATHAAYYTNCAYTCNCARATHCAYACNTTYCARATHGAYATG GAYAARAARAAYAARGARYTNAGYGARAARACNAARGARYTNGTNGGNTGYAARGARGAR GTNGARAARYTNAARMGNGARYTNGAYMGNYTNAARAAYCCNCCNGARYTNTGYGARAAR TCNAGYCARACNCAYGCNCCNTGYGARGTNTCNACNYTNGARAAYGTNAARCCNTCNATG ATGGGNGARMGNGARMGNACNATHCARACNYTNCARGARGARYTNGAYGARYTNAARACN CARGTNYTNGGNATGGAYGGNMGNCAYGARMGNGARAARGGNCARTGGYTNGARGARAAR AAYAARGTNATHMGNTAYCARAARCARYTNCARYTNAAYTAYGTNCARATGCARMGNAAR AAYTCNGTNYTNGARACNGARGTNCARCARYTNACNYTNGARYTNGARAAYMGNGAYATG AARYTNATHGCNYTNAGYGGNGARGARAGYGTN---------TTYTCNYTNTCNYTN--- YTNGCNGCNGTNYTNAAYYTNGGNTGYYTNATGTAYATGTAYATGTGGCARCCNTCNYTN GAYTCNYTNGTNCCNTAYTTYATGGTNATGGGNGTNTGGGGNATHACNGAYGGNTTYTGG ATHACNCARACNAAYAGYYTNATGGGNGTNATHTTYCCNACNCARTAYGARGARGCNTAY GCNGGNYTNMGNATGACNCARGGNYTNAGYGTNGCNGTNGCNTTYGGNTAYTCNAGYGCN YTNTGYATGACNYTNAARATHTAYATHATGGTNGTNATGTGYGTNGTNGGNYTNGTNGGN TAYYTNGTNATGGARACNAARCAYMGNMGNGARAAYACNAARCCNTCNTAYGARYTNAAR GTNACNTCNGTN------------------------------------------------ ------------GTNATHGCNACNGAYGGNGGNMGNTAYGAYGTNAAYATHGGNGARMGN CARMGNAGYGCNGTNTAYTGGGARGARGCNCCNACNGARGTNMGNMGNTGYACNTGGTTY TAYAARTCNGARGGNGAYAAYMGNTTYATHCCNTAYGAYGARGARTTYGCNGGNAARYTN GARGARGARTAYAARGTNGCNYTNYTNAGYAAYGTNTGGCAYAARMGNYTNGARTTYCCN GGNGGNGARACNATHGTNATGCAYAAYCCNAAYGTNATHGTNCAYTTY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GARAARGARYTNGAYMGNMGNCARAARYTNMGNGARMGNAARMGNGTN CARMGNCARAAYCARGAYTTYGCNGARMGNGARMGNYTNMGNGCNMGNGGNMGNATHAAR GCNYTNMGNGARGAYCCNATHTTYMGNCARTTYGARMGNCARMGNGAYMGNGARMGNMGN MGNAARGCNMGNYTNYTNAAYCARTCNCARMGNATHCARGARMGNGAYMGNGAYAARGTN MGNAARTCNATGATGMGN------------AARGCNGGNTTYGCNCAYATHAARTCNGAR TTYYTNYTNYTNGAYTAYAARCCNAARYTNCARACNGARTAYYTNAGYAARGARGTNAAR GARAARATGGARGAYGAYGARAARAAYCARGAYGAYGCNGAYGAYGGNAAYGAR------ ------------------------------CCNCCNTCNAARAARACNAARYTNACNGGN MGNAAYAARCARMGNCCNMGNAAYCARMGNATHGARGARAARGAYAARYTNTGYCCNGCN ATHAARGARGGNAARGARTGYAARTTYGGNGAYAAYTGYAARTTYAAYCAYAGYGTNAAR GAYTTYYTNGARAARAARMGNCCNGAYATHGAYGARAAYTGYCCNGTNTTYAARACNTGG GGNTAYTGYMGNTCNGGNGTNAGYTGYMGNTAYGCNAGYAGYCAYYTNGGNGARAAYTCN GARAAYYTNACNAAYAARGAYYTNTAYGARACNATGAARACNCCN---MGNTTYYTNAAY YTNYTNGAYGAYGARACNMGNAARAARYTNTGGAARMGNAARTAYGAYTTYCAYMGNTCN ATGGARTCNGTNAARAAYGTNCARAAR--------------------------------- ------------------------------------------------------TCNTCN GARAAYTCNAGYAAYAGYAARGARTGYGAYAAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------GGNAAR GARGARGCNGCNAAYACNACNGAYGAYAAYGAYGTNCCNATHACNTCNMGNGARGTNAAR AARATHGAYTTYCAYAAYAARYTNTTYYTNGCNCCNYTNACNACNGTNGGNAAYYTNCCN TTYMGNMGNGTNTGYAARGAYTAYGGNGCNGAYATHACNTGYGGNGARATGGCNYTNGCN TCNCARYTNYTNAARGCNAARGCNTCNGARTGGTCNYTNATHAARMGNCAYTCNAGYGAR GAYATHTTYGGNGTNCARGTNTGYGGNGCNTAYCCNGAYATGATGACNAARTGYGCNCAR GTNYTNACNGARACNGCNAAYATHGAYTTYATHGAYATHAAYTGYGGNTGYCCNATHGAY ATGATHTTYCARAARGGNAGYGGNAGYGCNYTNATGGGNAARGCNTCNMGNYTNGARAAY ATHTGYAGYAGYATGATGGGNGTNATGGGNGAYGTNCCNYTNACNGTNAARYTNMGNACN GGNGTNTAYGAYAGYAARAAYGTNGCNCAYAAYATHATHCCNMGNYTNMGNGAYGCNGGN GTNTCNYTNGTNACNATHCAYGGNMGNTCNMGNGARCARMGNTAYACNMGNATGGCNGAY TGGGARTAYATHGAYTCNTGYGCNAARYTNGGNAAYCCNATGCCNGTNTTYGGNAAYGGN GAYGTNYTNTCNTTYGARGAYGCNAAYYTNCAYATGGARAARCAYGGNGTNTCNGGNGTN ATGATHGCNMGNGGNGCNYTNATHAARCCNTGGYTNTTYACNGARATHAARGARCARMGN CAYTGGGAYATHTCNTCNGGNGARMGNTTYGAYYTNYTNAARTCNTTYACNAAYAAYGGN YTNGARCAYTGGGGNTCNGAYCAYCARGGNGTNGARACNACNMGNMGNTTYYTNYTNGAR TGGYTNTCNTTYYTNTGYMGNTAYATHCCNGTNGGNGTNYTNGARCARGTNCCNCARAAR ATHAAYGARMGNCCNCCNTAYTAYATGGGNMGNAAYGARYTNGARACNYTNATGGCNAGY CCNTGYTGYGCNGAYTGGGTNAARATHAGYGARATGYTNYTNGGNCCNGTNCCNGAYAAY TTYCARTTYYTNCCNAARCAYAARGCNAAYGCNTAYCAR--------------------- ------------------------------------------------------------ ---------------------------MGNTTYGGNYTNCCNAGYGARGTNACNGARGCN AARYTNGARAARYTNGTNGAYGGNGARATHGTNATHAARGTNGAYTAYAARGGNAGYACN AGYTAYMGNAAYGCNTCNAARTGGMGNAARAGYATGACNGGNTGYTAYGTNCARAAYTCN ACNACNATHTCNACNAARATHATHGARGGNATHYTNGCNYTNTCNAARGCNAARYTNGAR ACNAARCCNACNATHAGYGGNACNTCNAARYTNTGYGARGCNYTNACN------------ ------------------GCNGCNGAYGARGCNGGNGTNACNATGGARGARATHGARTCN TGGYTNACNGARAAYTGYGARGGNTTYGTNAAYYTNAARAGYCCNYTNACNATHGTNYTN AARMGNGARATHGAYGCNGGNMGNGTNACNAARYTNMGNAGYGGNMGNTTYGTNATHTCN TGYGCNCARAARGAYGARYTNAAYAAYGAYGCNATHAARYTNTTYGGNGCNAARAARACN GAYTCNAARATGAARACNCARMGNGGNMGNACNMGNAARAAYGTNGTNTCNCCNAGYAGY YTNGARCCNGTNTCNGTNTAYTGYMGNATHMGNCCNYTNGAYGAYCCNGAYGARGTNACN TGYATHAARCCNATHGGNGARACNGTNGTNCARYTNCAYACNCCNGARAAYGCNGCNCCN MGNAAYGGNCARTTYAARGARATHCARTAYACNTTYCARCAYGCNTTYGAYGARTGYTCN ACNCARMGNACNGTNTTYGAYAARACNGCNYTNCCNYTNGTNGAYGAYYTNYTNGCNGGN AARAAYGGNYTNYTNTTYACNTAYGGNATHACNGGNTCNGGNAARACNTAYACNATGACN GGNGTNCCNCARGAYCARGGNATHYTNCCNMGNTGYYTNGAYGTNYTNTTYAAYAGYATH GGNGAYAARCARGCNAARAARTAYGTNTTYACNCCNGAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------AARTCNCARGAYCARGARGAYGARATHMGNTCNYTNAARAGYTCNGAR ACN---------------GCNMGNTCNCARTCNGARGARTCNGARAGYYTNGTNCARGGN YTNGARAGYGARGTNTCNTCNYTNAARGARGARAAYAGYGARYTNGARAARGCNYTNGAR GARYTNGAYACNCARCARTCNCARGCNYTNTCNCARYTNATHAGYCARMGNGAYAARATG GCNGCNCARATHGCNCARCARGARGCNGARYTNGARCARTGYMGNACNCARATHGARTCN YTNGARTCNACNATHGGNGAYATGAARGTNAAR---------GTNATHGCNYTNGARGAR AARTGYGARAARTAYGARCARGARYTNTTYGARTGGAARGAR------AARTGYGARGCN ATGGARGGNAARGTNAARGAYYTNAARGARAARTTYGARAARGGNGGNYTNGTNATHAAY GAYYTNCAYATGGAYAARCARGAYYTNCARTCNCARYTNGCNACNGCNAARGARGARATG CARGCNAARGTNGCNAARYTNAARGARGGNMGNYTNGARAARGCNGARYTNCARAARGAR AARAARGCNYTNGARGARMGNYTNACNGAYGCNGARGARCARYTNACNGARATGGARGCN GARGTNGARAARTGGCARCARYTNAAYGARGAYAARCARGTNCARTCNCCNACNGTNGGN AARCARGARGTNGARTGYTCNMGNYTNMGNACNMGNYTNGARAGYATGGARYTNGARAAR GARGTNATHAARGARGARTTYCARTGYYTNATHGAYGGNGGNAGYAGYMGNGTNAAYMGN ATHGCNTCNGTNGCNGAYTCNGCNTTYCARCAYATHTTYGARGARGARYTNAARGTNMGN CARMGNYTNGARGARGAYGARGGNGCNGTNCAYGARYTNAARGARTAYGTNGARAARYTN MGNGGNGARMGNCARAGYYTNAARGARAARGTNGCNGTNYTNACNACNGARAARAAYGAR YTNGAYGCNGCNGCNTCNGARMGNGARAARGCNTGYGCNAARCARGTNGARAARTCNGAR GCNGARYTNMGNAGYAARGARYTNGARGTNGCNGARGTNAARTCNGARYTNGARMGNATH MGNGGNGARAARYTNAGYYTNCARGARAGYTTYACNAAYATGCARMGNGARAARCARAAY YTNGCNGAYYTNTTYGAY---------AGYMGNGARCARGARYTNAARYTNGGNAARGAR ACNGGNGAYAARAGYYTNCARTCNYTNAARGARATGAGYTCNGARATGGAYGCN------ ------------------------------------YTNMGNGARCARGTNAARGARATG GAYGGNYTNMGNCAYYTNGTNGGNGARAARAARAGYGARGTNGARAARYTNACNACNGAY TGYGAYTCNTAYMGNAAYGARATHAARTCNATHAARTCNGARATHTCNMGNYTNGARGGN YTNTGYGGNGARAARGARAARGARYTNGARAGYGTNAARGARMGNATGCARCARTTYGAY MGNGAYYTNGGNGARATGGARGARTCNGTNAGYGTNAGYAARMGNCARCAYGARACNGAR ATGAARGAYAARGARAARGARATHMGNGARATGGTNGCNATGAARATHGAYYTNGARTCN GARYTNAARCARYTNAARGAYGARATGGARYTNGTN------------YTNTCNGAYCAR ACNMGNGGNGCNGARGARGGNGARGARYTNAARCARGARMGNGARGCNMGNGARGAYAGY ATHTCNCARYTNGARGCNGARYTNTCNATHTCNCARGARAARATHGARAGYYTNMGNGAR GARYTNTCNCARGCNAARGARATGGTN--------------------------------- ---------GARGARGCNAAYAAYGAYMGNGAY---------AGYGCNAGYAAYMGNAAY AARAAYTCNYTNGTNGARGAYMGNATGGTN------------------------------ ---------------------------------------------CARYTNGARTCNMGN CARCARAGYAGYAGYCAYYTNCCNCARTCNTCNGGNCCNAGYAAYGAYGCNACNTGYATH GARTTYATGGARMGN---------GGNGTNGCNAAYCARYTNYTNACNTCNCCNTCNCCN GTNMGNAGYGAYTAY---------------ACNGAYGARACNGAYGAY------CARCAY GARMGNTTYGARYTNYTNGARAARGARATGGARGARYTNMGNGGNAARYTNAGYGARAAR GAYGGNGTNGTNTCNGARYTNCARMGNTCNAAYGCNTCNYTNYTNGARGTNYTNGARAAR AARGCNAAYGGNGAYAAYAAYYTNGGNAAYMGNYTNGCNACNCAYAARYTNGARACNGAR YTNAARAGYYTNMGNGCNGARMGNGARCARATGATGGCNGTNGTNAGYGARAARTCNMGN GARAAYTCNTCNYTNAARTCNGARATHCAYMGNYTNATGGAYACNGTNTCNGCNGGNCAR AAYGCNYTNAGYMGNGTNCARGARGAYAAYMGNAGYYTNGARCARCARCARCARTCNCCN CCNMGNGAYAARGAR---GAYGAYGAYGAYATGAARMGNGARGCNYTNAAYACNATGGCN MGNYTNGTNMGNGAYAARGAYACNGARATHGARGCNYTNACNCARAARAAYACNACNYTN YTNGCNGTNYTNCARGARCARGGNAGYGARTCNCARGCNGCNGCNCAYYTNGGNCCNYTN YTNCARGARAARGARGCNYTNGGNCARMGNATGGCNGCNATGATGGCNGARMGNGARCAR YTNATHGCNTGYGTNACNCARAARCAYTCNGARTCNYTNGCNTTYCAYGGNGARATHCAR MGNYTNACNGCNGTNYTNMGNGARACNCARGARGTNGCNGAYACNGCNAARTCNGARTAY GCNGCNYTNATHCCNGCNTTYGARGTNAARACNCARGCNYTNGTNAGYACNCARCARGAR YTNGTNGARTGYAARCARAARYTNGCNGARACNGARGTNMGNCAYGGNGARYTNATHCAR MGNTCNAAYAGYAAYCARCAYATHCARCARAGYTCN------------TCNTCNYTNGGN GARYTNGARGCNGARYTNGARAARTAYMGNMGNYTNGARMGNGAYTAYAARGCNATGGTN GTNGARMGNGAYGGNCARATHCAYGGNYTNTCNCARMGNATGAARGCNYTNGARGARACN GCNACNTCNAARGARGCNGARTGYGCNCAYYTNAARAARCARGTNGAYAAYTCNAARTTY CARYTNACNGGNYTNATGGCNGARATHGCNGAYGCNAARTCNGARAARGARYTNGTNCAR CARMGNAGYCARTCNCARGGNGARCARTCNACNAGYYTNMGNAAYAGYATGAAYCARYTN MGNYTNTCNGTNCARGAYAARGAYGTNGARATHTCNTCNYTNMGNGARCARYTNGGNACN YTNAAYTCNGTNYTNCARAGYCARCARGGNGARCARAAYCARGTNGCNYTNYTNATGMGN GARCAYGARGCNGTNGTNGCNACNAGYMGNCARYTNCARCARGARMGNGAYTAYAAYGCN ATGYTNGCNGARCARMGNAGYCARGARTGYGGNACNGCNACNATGGARYTNTCNGCNCAR AARGAYAARGTNTTYAARYTNGGNMGNGARYTNGARMGNYTNMGNAGYCAYYTNATHGAR ATHGARGARGGNTAYACNAAYGARGCNYTNGARGCNGARGARMGNGARAARGARYTNMGN AAYAARYTNGCNGTNGCNGARGARCARYTNYTNAGYTCNACNTCNCAYGTNCARYTNGCN AGYCARGARTCNCAYMGNCAYGTNGARAGYYTNCARGARCARYTNCAYCAYGTNGCNAGY CARMGNGAYGCNGCNTAYATGCARGTNGCNACNACNCARGAYCARTGYGARCARTAYGCN GCNTCNYTNAARAAYYTNCARYTNGTNYTNGARCAYTTYCARAARGARAARGARACNGCN GTNTCNATGGARACNGARAARTAYCARGARAARGCNAAYAARCARACNGCNAAYGTNAAR GCNYTNGARAARGARYTNCARGCNACNMGNAGYGAYYTNACNGARGCNYTNGAYGGNYTN GARGCNGCNTCNMGNYTNAGYGARCARYTNGAYMGNAARCARGAYGCNYTNGCNGCNYTN AARGARGARGTNCARATGMGNGARCARGCNYTNAARGCNGCNGARGARGARATHGCNAAR YTNAAYTCNAGYAARGARGCNAARGTNGAYAARATGYTNATGCAYAAYATGGTNYTNACN TGGYTNACNTCNCCNGARAARAARMGNAGYGARATHGTNCARYTNATHGGNCAYGTNYTN GAYTTYAGYAAYGAYGAYTTYAGYAARATHGARTCNGCNCAYAARCARGAYAGYYTNTGG ATHGGNTTYTTYMGNAGYCCNAARGCN---GARCCNACNCCNACNAARGCN------GAY CARTCNTTYTCNCARYTNTTYGTNAARTTYYTNGARAARGARTCNACNGCNCCNCCNACN CCNGTNCARYTNCCNGTNGARGCNATGGCNGCNGARGCNCARGCNMGNCAYAARACNAAY TTYAAYCCNTTYACNGCNCCNMGNCAYGTNACNCAYTCNGGNYTNTCNGCNTCNACNTCN TCNTCNTCNTCNTCNCAYYTNYTNATGATGCCNGAYACNCCNCAYCCNTCNCCNYTNTTY GCNCCNGTNACNAGYGTNTCNAGYGCNGGNGARAGYGCNATHYTNAARGAYGTNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GAYMGNGGNMGN GARMGNYTNTGGGTNGGNACNMGNMGNTAYATGGCNCCNGARYTNYTNGCNAARACNYTN AAYCCNGCNCAYTTYGARTCNTTYMGNTGYGCNGAYGTNTAYGCNTTYGGNYTNGTNATG TGGGARATHGCNMGNMGNGCNMGNCCNTAYTGYGARGARTAYMGNGTNCCNTTYTGGGAY YTNGTNCCNGGNGAYCCNAGYGGNGARGAYATGAARAGYGTNGTNGTNGAYMGNGGNYTN MGNCCNGCNATHCCNAAYAAYTGGGAYCARGARCARYTNATGAARGARATGGARAARYTN ATHAARGGNTGYTGGGCNCARCAYCCNTCNAGYMGNYTNAAYATHYTNMGNGTNAARAAR AAYYTN---CARGCNYTNMGNTCNCARTCNGARCARATGATGGARAARMGNGARAARYTN TCNGGNAARATHYTNGAYGGNAGYACNACNACNAAYAGYGTNGCNACNACNTCNAGYAAY ATGYTNTTYAGYGTNGARGAYTGGAARCARGGNATGGAYYTNYTNTGYGARGAYYTNAAY ---------YTNTTYAARGAYAAYTTYGAYTGYYTNTCNCARCAYGCNCCNMGNATHTCN AGYTGYATHYTNATHMGNACNCARATGTTYAARMGNGCNGTNYTNGARGCNGGNATGGCN ACNCAYAARACNYTNCAYGAYATHACNTGYAAYTTYGCNGARAAYATHGTNAAYTGYYTN GARMGNCCNYTNGARMGNACNTGYCCNATHYTNGTNGTNGAYACNATGGTNACNGCNYTN CAYMGNTTYYTNCCNCCNGCNTGYGCNCCNGTNCCNATHGTNCAY---CCNGCNGARGAR GAYGGNGARATHGAYGARAAYCCNYTNCAYTCNGTNYTNGARACNGTNATHGTNGARGGN GGNGGNGGN--------------------------------------------------- ---------------------------------------AARATHMGNATHYTNAARAGY CCNCCNGTNACNGARATHAARAAYGCNAGYATGCCNACNMGNACNAAYYTNAARCARCAR YTNCARMGNCARCARYTNTAYGAYCARGARAARMGNCARAARTCNATH---AARACNACN TAYGTNACNGGNTCNMGNGGNATHACNGTNCCNCAYGTNATHGARTCNTCNTCNGTNCCN TCNAAYGTNYTNCARGTNMGNACNCARYTNCARCAYCCNACNAARTAYCAYGTNMGNCAR AAYCARAARMGNCARGTNGARAAYTTYYTNCAYGARCAYGARAAYAGYCAYYTNCCNATH CARTCNYTNCCNTCNAAYGCNGCNGARTCNTCNTCNYTNCARCAYCARCARCAYCAYATH CARGCNTCNAGYAGYGCNCCNGARCCNGAYYTNTCNAGYGARTCNATGGGN--------- ------AAYGARTTYAAYTCNACNGAYTTYGAYYTNYTNGGN---YTNAGYTGGGTNGAR CARCARGAYYTNGGNTGYATHYTNAAYGAYAGYGGNYTNATHGARATHCARCCNTCNYTN GGNACNGARGGNYTNAAYCARGCNTCNYTNGTNCCNAGYYTNGAYGAYYTNAAYCCNGAY GGNAGYGTNTCNCARGGNTCNGGNGTNAAYTCNTGYCCNACNAGYCARTAYCAYTCNCAR TCNGCNGARCAYGGNGGNAAYATGTCNGTNCARGAYGARATGTGGMGNAARGARMGNATH AARAARGAYAAYCAYAAYATGATHGARMGNMGNMGNMGNTTYAAYATHAAYGAYMGNATH AARGARYTNGGNGGNYTNYTNCCNAARTCNATHGAYCCNGAYTCNMGNCARAAYAARGGN GGNATHYTNAARGCNTCNGTNGAYTAYATHAARATHYTNCARGAYGAYCARMGNAARTTY MGNAAYATGYTNGAYGARAARAARAARGCNGARYTNGAYYTNMGNAARGTNYTNYTNMGN GTNAAYCARATGAAYYTNGTNATGMGNTCNCAYGGNATHGARGCNACNGGNYTNGARAAY YTNGARYTN---CAYTCNGCNACNGCNGGNAGYACNAAYTTYYTNACNACNCCNGTNGTN YTNACNCCNMGNAGYCCNGTNATGCCNTCNACNCAYACNGAYACNACNACNGTNAAYCCN CAYACNAGYGTNGARGAYYTNATGATGGAYGAY---TCNCCNGTNAGYGGNGAYCCNATG YTNATGTCNGARCCNGTNAGYCCNGARCCNGAYGARTAYCAYTTYAAYTTY--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------CCNAGYGTN MGNAGYTGYTTYGARAARGCNAAYGGNMGNCCNGARATHGARGTNTCNCAYTTYYTNGAR TGGYTNAARYTNGARCCNCARTCNYTNGTNTGGYTNCCNGTNYTNCAYMGNYTNGCNGCN GCNGARACNGCNAARCAYCARGCNAARTGYAAYGTNTGYAARAAYTTYCCNATHATHGGN TTYMGNTTYMGNTGYYTNAARTGYTTYAAYTTYGAYGTNTGYCARGTNTGYTTYTTYGCN GGNMGNACNGCNAARAGYCAYAARYTNACNCAYCCNATHAARGARTAYTGYACNACNACN ACNTCNGGNGARGAYGTNMGNGAYTTYTCNAARGTNTTYAARAAYAARTTYAARTCNAAR MGNCAYTTYCARAARCAYCCNMGNMGNGGNTAYYTNCCNGTNGARTCNCAYYTNGARGGN GAYAGYYTNGARAGYCCNAAYCCNTCNCCNCARCAYAGYATHTCNCARGAYATGCAYTCN MGNYTNGARATGYTNACNAGYMGNATHGCNGARGTNGARCARMGNCARGGNGAYTCNACN GAYTTYGARGAYGARCAYCAYYTNATHGCNCARTAYTGYTCNAGYYTN------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------MGNAARMGNAARAARTCNAARAARTCN AARGGNAGYCAYTCNGCNGARGAYGARGARGCNGAR---------AGYMGNATHGAYMGN GCNYTNCAYTAYYTNMGNAARTGGCARAAYGAYMGNAARGGNTGGAARTTYGARAARGTN AARCARATGATHYTNYTNAAYTCNATGTAYGAYGTNAARAARYTNCCNGARGCNGAYTTY GARATHYTNYTNTCNTAYYTNGAYGGNYTNGTNGGNAARGGNMGNGARAARACNYTNGAR GARGCNGARAARAARYTNAAYGTNATGGAYGARGCNGGNYTNAARYTNGCNTAYATHGAR GGNTGGAARYTNATHAAYYTNGCNAAYGARACNTTYGGNTTYACNGGNTGGTCNCAYTCN GTNACNAAYCARGCNGTNGAYTTYGTNGAYCAYGTNAAYGGNAARTAYTAYGTNGGNGTN GGNGCNACNGTNMGNGTNACNYTNAARAAYGGNGTNTAYCAYGARGGNGTNGGNTAYGGN GTNAGYGARGGNATGMGNTCNAARGCNYTNTCNYTNGARAARGCNMGNAARGARGCNGCN ACNGAYGCNYTNAARMGNGCNYTNAARTCNTTYGGNAAYAGYYTNGGNAAYTGYYTNAAY GAYAARGAYTAYYTNAARTAYATHAAYAARGCNCCNAARCCNCCNCCNTCNAAYTAYAAY ATHGAYGARATGAARMGNGARACNGARGAYAARCARGTNATGAARGCNMGNATGGCNGCN CCN---GTNGARAAYAGYTTYATHCCNTGYGAYGAYTTYATGAARTTYCARCAYGCNYTN AARAARATGMGNYTNATHGAYGAYMGNATHATHCAYGCNYTNAAYMGNAAYATHCCNACN CARTCNTTYCARGGNAAYGTNGAYACNGCNTTYAAYTGYAARCAYATHTAYGAYGAYATH CARACNTCNTAYAGYCAYMGNGARAARTCNATHCARCAYTGYATHMGNYTNGTNGGNGAY GAYGTNAARAARYTNAAYGAYAARMGNCARCARGAYCCNGAYAAYATGGAYGTNACNMGN ACNYTNMGNMGNGARCARACNAARYTNMGNYTNATGCARCARGARATGAGYGTNGARGAR GTNGTNAARGAYMGNACNYTNAARGTNATHGAYGCNAARGAYATHYTNTGYGTNGAR--- ------YTNGCNGGNYTNTGYCAY------------GAYYTNGGNCAYGGNCCNCAYTCN CAYATGTTYGAYGGNAARTTYATHGCNAGYTTYCCNGGNAAYGCNAAYTGGACNCAYGAR AARGCNTCNYTNGAYATHYTNGAYYTNATHATHGARGAYAARGGNYTNYTNMGNAARGAY GGNATHYTNTGYAARCAYGGNYTNACNGARACNGAYATHATHTTYATHAARGARYTNATH AAYGGNCCNAAYATHCCNYTNAARAARGGNAARTAYMGNGGNGGNMGNGGNCCNAARAAR TCNTTYYTNTAYGARATHGTNTCNAAYAARGAYACNGGNATHGAYGTNGAYAARTGGGAY TAYTTYGCNMGNGAYTGYCAYCAYYTNGGNATGGTNAAYAAYTTYGAYCAYAARMGNTAY ATHAARTTYGCNMGNGTNYTNGARGTNGAYGGNAARATGACNATHTGYGTNMGNGAYAAR GARATHGGNAAYYTNTAYGARATGTTYTAYACNMGNTAYAAYYTNCAYMGNMGNGCNTAY CARCAYMGNGTNAGYTGYGCNATHGARGCNATGGCNYTNGAYGCNTAYATHAARGCNAAY GAYTTYATHACNTTYCCNGGNAARACNAARMGN---AARATGTCNGARTGYATHGARGAY ATHACNGCNTAYTGYCARYTNACNGAYGAYATHATGTGGCARATHTAYACNTCNTCNGGN GARGAYYTNMGNCCNGCNMGNGARATHATHACNMGNATHTAYAARMGNGAYYTNTAYATH TGYYTNAAYGARGAYAARGCNGAYMGNCCNCCNAARACNGTNGAYCARYTNMGNGAYGAR ATGATHCARTTYAGYCARATGGCNYTNGARGGNTCNCAYTTYMGNYTNGARGGNTCNCAY TTYMGNYTNGARATHGTNTAYATGGAYTTYGGNAARAARGAYCARGAYCCNYTNGARGCN ATGMGNTAYTAYTCNAARAARGAYCCNAAYACNCCNCARAARYTNAARCCNTCNGGNYTN YTNGTNCCNCCNMGNTTYYTNGAYATHYTNATHMGNGTNTAYAGYMGNACNAGYGARAAR AARACNTGYGARYTNATHCARGARAGYTTYGAYAARGCNGTNATGGCNYTNYTNGTNTGY GCNGTNTCNAARCCNGTNAARMGNGGNCCNCCNGCNAARCCNGTNGTNGARGGNAAYTCN CCNGARGAYAARGCNCARGARGCNATGGGNYTNCAYTAYGARCAYTAYYTNAARGARGTN GTNGAYGTNYTNGARAGYGAYCCNGAYTTYAARCARAARYTNGARAGYGCNAAYGTNACN GAYATHAARAGYGGNAARATHGCNATGCAYYTNAAYYTNGTNAAYCAYACNGTNMGNGGN AARYTNGAYGARYTNAARMGNAARGARYTNAAYMGNYTNTCNCARYTNGCNMGNYTNGAR ATGCARGCNAARACNGGNATGAARAAYTTYCARATHCCNGARCAYYTNGAYGTNCARAAY CAYAARACNTTYGARATHAARGAYYTNGARATHYTNATHAARAARACNACNAAYGAYYTN GARAARYTNGAYGARCARMGNMGNGARGARTTYAARGAYTAYGARATGGARAARAARTTY GARGCNGARGARCAYYTNAARCARYTNAARGARGAYGAYMGNAARAARGARGARGARMGN YTNGAYAARYTNAARACNGARCAYAARGCNCAYCCNAARYTNCAYCAYCCNGGNAGYAAR GAYCARTTYGARGARGTNTGGGAYAARCARGAYCAYYTNCARGAYCARGARTTYAAYCCN AARACNTTYTTYTTYACNCAYGAYGTNAAYGGNGAYATGGARTGGACNGTNGAYGARGTN GAYGCNGTNNNNCARACNGARYTNAAYAARGTNTAYGAYGGNMGN--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AARAARYTN CAYAARCARAARGARGCNATHACNTCNAARGGNAARATGGTNATHGCNACNAARGAYYTN CCNAGYAARATGTCNTGYGTNGAYYTNATGGTNGCNTTYGGNYTNCAYATHGGNTCNTGY TCNGCNTGYGTNGCNGTNCAYAARGAYGGNAARACNGARGTNATHGCNAAYGAYYTNGGN GAYMGNGTNACNCCNGCNGTNGTNGCNTTYACNGARYTNGARATHGCNGTNGGNGCNGGN GCNAARCARGGNGCNGTNMGNAAYGCNGCNAAYACNGTNGTNCAYGTNAARCAYATHATH GGNAAYGARAGYGAYGAYCCNCARGTNAARGARTAYATGCARAAYCAYCARGTNGARGTN ATHAAYCARAAYGGNCARGTNGTNTTYAAYGTNGARCAYAARGGNAARAARGCNCARTTY TCNCCNAGYAARATHATGGARATHATHTAYMGNAARATGYTNGARACNGCNCARAGYAAY AGYGGNGGNGARAGYATHGAYACNGTNYTNGCNGTNCCNTCNGAYTTYTCNATHAARCAR MGNAAYGTNYTNMGNGARGCNGCNACNAARGCNGGNTTYACNGTNYTNMGNGTNATHAAY GARCCNTCNTCNGCNATGYTNGCNTTYGAYGCNGGNCARTAYGAYGAYACNGARCAR--- TTYAARGCNYTNGTNTAYMGNYTNGGNGGNACNTCNCAYGARGCNACNGTNATHAGYGTN GARCAYGGNATGTAYTGYYTNYTNGAYAARGCNATGGAYAAYCARTTYGGNGGNGAYMGN YTNACNGARGTNYTNATGGAYTTYYTNGCNAARGARTTYAAYMGNCARTAYMGNTGYGAY GTNAARGARAGYAARMGNTCNATGAGYAARYTNAARYTNGCNGCNGARMGNTGYAARCAY TCNYTNAGYGCNGTNCCNAAYTCNCARTGYGAYGTNGAYACNYTNTTYGAYGGNATGGAY TTYTCNTAYAAYATGTCNMGNGCNMGNTTYGARATGYTNTGYCARCCNYTNGTNTCNCAR TGYACNCARYTNGTNCARCARGCNYTNGAYAARGCNGGNTGYTCNAARGARAGYATHTCN AARGTNATHATHTGYGGNGGNGGNGCNAARTCNCCNATGGTNAARAARGCNATGGCNGAY TTYYTNCCNTCNTCNACNYTNYTNAAYTCNATHCCNGARGAYGARATHATHGCNATHGGN GCNGCNAARGARGCNGCNYTNYTNGARGGNGAYAARGARGAYCARCAYAARGTNGARGAY CARAAYACNACNACNTTYMGNTCNYTNTCNAARGCNATHTGYYTNMGNGTNAAYACNCCN GARYTNCARGTNATHYTNCCNCARAAYTGYYTNATHCCNACNMGNAARCARCAYACNGTN ACNYTNCCNCARTCNCARACNAGYGTNAARATHGARGTNYTNCARGCNGAYGARCCNATH ACNCCNGARACNGARGCNCARYTNYTNGCNAARATHGTNYTNMGNGAYYTNCCNCCNGGN TCNACNATHAARTCNAGYTTYCAYYTNACNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GARGARGAYGAYGARGARATHATHGGNMGNACNGAY GAYGARACNGAYGAYGTNACNGAYTCNGAYGGNGAYGAYGAYGCNGAYGARGGNGTNMGN MGNGGNGARCCNAAYAARTTYGAYGGNYTNTGYGAYGGNGTNATGAAYGCNATGGCNYTN GTNCAYGCNGCNYTNCARGAYYTNYTNGARATGAARGAYGARATGYTNMGNCAYTCNYTN CCNCCNACNYTNATGGTNCARYTNGCNATGGTNAGYGGNMGNGTNTTYMGNAGYATHAGY GAYYTNGGNAAYCCN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GAYCCNMGNGAYCARAAYGCNGTNGTNAAYACNTTY TAYYTNACNAGYAARAGYGAYTGYMGNGAYGARTCNAARAAYATHTTYAAYAAYGARGCN ACNATHATGGGNTAYAAYACNMGNAAYATHGGNACNGGNCCNACNTCNTGYACNATHMGN ATHACNTCNACNTCNATHTAYCCNGGNGTNCARYTNCARATHMGNATHGTNTCNATGAAY ATHCARGAYTGYMGNACNTCNYTNTCNATHTAYGAYGGNGARGGNACNCARAARYTNGGN TCNTAYGAYTGYAAYAGYAAYCARAAYYTNAAYMGNYTNCARYTNGTNACNTCNGGNGAY ACNGTNTCNTTYATHATGAAYMGNAAYAAYCCNGAYAGYCAYGCNTTYGAYATHGARATH AARGTNACNCCNATHMGNAGYGGNYTNAAYCCNGAYTTYGAYAAYAAYTAY--------- TTYAGYTTYCARAARTTYGAYCARGAYGCNATHGTNGGNATGATHGGNGGNTTYTAYGGN YTNGTNYTNATHATHTGYGTNGGNYTNYTNTGYTAYTTYAAYATHAARTAYMGNGGNYTN GAYAARAARTGGGARACNCAYCARYTNGARACNATGAARACNGCNACNAGYTTYGAYGCN MGNAGYCARGTNACNCARCCNGCN---CCNTGGTCNGTNAGYGGNACNAGYCARMGNGGN GGNAGYAGYCARTAYCCNMGNTCNACNACNGAYACNTAYTCNMGNAARGGNGCNGCNACN MGNAGYGARGAYGGN---TCNAGYGTNTAYGAYCAYGAYGAYAARTTYCARCARMGNAAY YTNATGAAY---CARMGNGGNACNMGNAAYAAYGGNMGNGAYAARATGGCNTCNCARAAY TCNACNTAYGAYGAYGARGAYAAYCCNGAYAAYTTYAARGARAARGTNATHACNCCNMGN GTNMGNCCNGGNAARCCNMGNAAYCARMGNCCNCCNTCNTTYGARGARGCNACNMGNGAY AGYTCNTCNGGNGGNTAYTCNGAYGARGARACNGARGARTCNTCNAGYGAYGAYGGNTCN ACNMGNAARMGNYTNACNACNTCNTCNGARGGNGARGAR------AGYGARTCNGARACN GARTCNGARTCNGARTCNGARMGNAGYAAYGCNAGY---------------TCNGCNMGN GGNGCNAARGCNAARMGNGCNAARGGNAARAARTCNAARGARAARTCNAARCCNMGNMGN MGNMGNCARTCNTCNACNGAY------------GAYGCNGCNTCNTCNMGNMGNTCNGAR CCNMGNGCNMGNMGNCCNCCNGCNCARCAYCCNCARCARGCNGCNCCNTAYAAYCCNTAY CCNCCNGGNCARTTYGTNCCNGTNATGGCNGGN---CAYCCNCARTTYCARCCNGTNCAR ATGGTNCCNCCNAAYTAYCCNCCNCCNCARTAYCCNGGNCARAAYGCNCAYCCNYTNGCN TCNTCNCARGAYGTNAARCCNACNGAYCCNCCNGTNTAYTCNTAYYTNGTNMGNMGNGGN TAYACNCCNATGGAYAAYMGNAAYTCNTCNGCNGGNAGYGTNAAYTCNGGNCARMGNCCN CCNGCNCCNMGNMGNGARGARCCNGAYATGCCNYTNCARAGYGGNGTNGARTAYATGMGN MGNAARATHTCNCCNCCNATHAARATHTCNAARATGGARAAYYTNYTNCCNCARTCNGAR CCNAARYTNGTNGGNGARYTNGTNCARGCNYTNCCNAARGTNCCNYTNTCNTCNTTYGTN GARTGGTTYATHGARACNTCNCAYCCNGAYCARTTYACNGCNAAYTCNGARGGNTGGAGY ATGACNYTNAGYTGYYTNMGNTGYAARCARAARACNCCNYTNCCNCCNCAYGGNGTNAGY GGNYTNCARCCNGAYYTNGTNYTNGARGAYATHYTNCARAARGAYTCNGARGARATHAAR CARATHGGNTGYACNAGYTGYAARGCNGARGAYAARGCNGTNGCNMGNTGYAARACNTGY GARAAYYTNYTNTGYCCNAAYTGYGTNACNGCNCAYAARTTYATGMGNTGYTTYGARGAY CAYCARGTNGTNACNTTYGARGARATGATHAARAGYGGNGARGGNATHGAYCAYYTNMGN AARCCNATGTTYTGYTCNYTNCAYCCNYTNGARAGYATHAARTTYTTYTGYTCNAARTGY TTYGTNTGYAAYGARTGYGTNTCNAARGTNCAYGCNTCNCAYGARAGYGAYGTNAGYCAR YTNACNCAYGCNGTNTGYAARAAYAARGARGCNYTNATGAARTAYGCNGARGARTGYGGN AARAARATHGAYAAYTGYGARAARATGAAYTCNAAYYTNAGYATGGCNTTYGARGAYYTN GARATGCARAARGAYAAYACNAARGGNYTNATHGARGARACNTTYCARAGYTAYAARGTN ATHYTNGARGARGCNMGNGAYGCNTGYYTNMGNGARYTNGAYGARYTNCAYGARAARMGN GARATHGGNYTNATGGARAGYATGTAYACNYTNMGNTCNMGNATGCARATHTTYAAYMGN AAYGGNCAYTTYGTNMGNMGNATHGCNATHMGNTTYATHGAYATHGTNGCNGGNYTNGAY ATHACNCCNGARGGNCAYATHGTNGCNGTNGAYAGYGTNTCNCCNACNGTNTTYMGNYTN ACNGARGCNGGNGARYTNATHAARTGGTTYGAYTGYAGYGAYTAYATGMGNGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------CCNGAYMGNTGGGARGCNTAYTCNAAR ATHGGNAARGTNATHTGYGGNACNAARATHATGCCNATHAARGTNCCNYTNAARGARAGY TTYAAYGCNTCNYTNCCNCCNGARGARGTNTTYTCNCCNGCNTCNYTNYTNGAYYTNYTN AARAGYAAYAAYYTNAARYTNGGNGCNGTNGTNGAYYTNACNTTYACNACNAARTAYTAY AAYAGYCARTTYTTYCCNGARAAYGGNATHAAYTAYAARAARGTNYTNACNAARGGNCAY GTNATHCCNAGYAAYCARACNTAYMGNCARTTYGCNAGYGCNATHAARGAYGTNGARAAR GAYGGNGARGTNATHTGYGTNCAYTGYACNCAYGGNYTNAAYMGNTCNGGNTAYYTNATH TGYMGNTAYATGATHGARGTNYTNAAYATGGARCCNCARCAYGCNATHAAYYTNTTYGAR AGYGCNMGNGGNCAYAARATGGARMGNMGNAAYTAYATHGAYGAYYTNATGMGNMGNYTN CCNGGNGTNTGYGAYGARGAYGARGAYCAYTCNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYCCNTTYYTNACNCARTGGAARAARAAYGGNCARGCNYTNAAYCCNGGNTGG GAYMGNTTYAARGTNTCNMGNGARGGNCAYYTNMGNATHAARGAYGTNCARYTNACNGAY GCNGGNYTNTAYACNTGYGTNGCNACNAAYGGNTAYGGNAGYGTNAARTTYAAYTAYACN GTNGTNGTNYTNGAYGARGARAAYAARGTNTTYCARGARGCNGAYAARATHYTNAARCAR TCNGAYGAYGARGAYGTNTAYAARGARAGYGCNGCNCCNTCNTTYGARGARYTNGAYAAR ATGMGNGARATGATGAAYYTNATGMGNCCNAARGGNTCNACNYTNMGNYTNGCNTGYAAR GCNAARGGNAAYCCNCARCCNCARGTNCARTGGTTYAARGAYTCNAARYTNTAYAAYCAR MGN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GGNGGNMGN GCNAGYCCNGTNTCNGARACNAGYMGNAGYTCNAGYGGNAGYCCNACNCCNAGYGAYACN AGYTCNCARAAYGCNGCNATHAGYCARCARGCNATGAAYGCNGCN---GCNATGAARAGY GARGARACNGCNAARYTNACNGCNTCNYTNAGYAAYTAYTAYAAYCARTCNYTNATHGGN CAYGTNYTNGGNTGGCARGCNGAYTCNYTNGARAARCARGCNTGYAARYTNTGGGARGAR ACNATGGTNAAYGGNAGYYTNCARTGY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------GGN YTNAGYCCNGARGGNATGGARMGNGARGCNAARYTNGCNTAYYTNAARACNTGGGCNGAR ATHACNAARGAYATHCAYGARCCNAAYATHTCNYTNYTNYTNCAYYTNCCNATHYTNYTN GGNTAYTGYCARCCNTCNAAYMGNAARYTNATGGCN------------------------ ---------TCNGCNAARTAYACNGARTAYATHYTNATHCAYYTNGAYGAYYTNAARACN AARTGYYTNCAYYTNACNACNTGYGTNAAYMGNYTNYTNTCNGGNCARMGNYTNATGTCN GTNYTNAARGGNGARAAYYTNAGYYTNAAYAARGTNTGYAGYYTNATHAAYACNAAYACN ACNAGYACNGARACNATGYTNGAYGGNAARTGYTCNATHCAYGARMGNYTNGAYATHMGN GAYGAYGTNGARGCNCAYATHMGNGAYAARATHGARAARAARYTNAAYTGGGARAAYGTN AAYATHTGYYTNGARAAYAAYTAYGGNGAYGARGARMGNACNACNTAYGTNCARGARYTN TGYGGNYTNGCNGGNGARCARGAYAAYATHTGYGCNAAYTAYAAYACNCAYAARCARGTN GARMGNTTYGTNAAYGARCARATHGARCAYYTNCARTGYAAYTGYAARTCNYTNGAR--- ---MGNGARCAYTCNGAYGARGGNATGTCNTCNGCNATGATHATHGGNYTNGCNGGNGGN GGNGTNTGYYTNYTNYTNATHTTYTTYATHYTNYTNTTYTTYTAYTGYCARAARMGNAAR MGNMGNMGNAARAARAARAARGGNCCNAGYGTNATHTAYYTNCCNAAYCCNAAYCCNGAY AGYTAYCCNGTNTAYCARGARATHTAYGAY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------ATGYTNGARGARGGNAGYGGNACNATGGAR AARAARTCNTCNACNMGN------CARTCNCARGGNCAYTGYAARATH---AGYGTNACN GGNGARMGNAARTCNGAYACNTCNAAYMGNCAYGGNTTYAAYMGNMGNTCNYTNTCNAAY ------GGNGGNGCNAARGCNCARGAYAAYGGNCARGCNCCNMGNCCNYTNCCNATHCAR AARTGYGAYMGNTCNTTYGGNGARAARMGNCARMGNCARMGNAGYTAYCAYGAYGAYMGN CARMGNGARAARGTNGTNGAR---GARGAYGGNTAYAAYGTNATHAGYACNAAYTCNMGN AARGGNAAYGCNAAYCAYYTNYTNAAYTTYCCNTAYMGNAGYCARGGNAAYGARYTNMGN CAYTAYAGYMGNAAYAGY------TTYAGYTCNCAYGGNCAYGGNGGN------TAYMGN AARGCNACNMGNTAYAARAARGARCARTTYYTNCARGCNAGYTGYCARTTYGTNGTNMGN GAYACNGGNGAYTAYACNGARCARGCNGTNAAYCCNGAYGCNYTNGTNGAYTGGAARYTN GTNGARYTNGTNMGNGGNTTYTCNACNGARCCNGTNACNTGYCCNATHTGYYTNCARATH CCNGCNGCNGGNAARATHACNAARTGYGGNCAYACNTAYTGYTGGGCNTGYATHYTNCAY TAYATHAARYTNGGNGARAARGARYTNCARAARTGYCCNATHTGYTAYGAYACNATHGAR YTNAAYGAYYTNAARAGYATHCARTGGATGGAYGTNCCNGAYTAYAAYATHGGNGAYGAR ATHGAYATGMGNYTNATGMGNAARTCNAARGGNTCNACNTTYGCNGTNCCNAARAAYCAR TGGGARGAYMGNCARGGNAARCCNYTNTAYATHCARGARGGNGARAAYAGYAARTAYGTN AARYTNYTNGTNGCNTCNTGYGAYCARATHAARACNGAYGTNATHGARATHGARMGNACN TCNYTNACNGTNCARATHGARGAYGCNGARGARTCNGARGTNCCNTTYATHGARATGGCN YTNGARGAYYTNTCNGCNMGNGARAARTCNYTN--------------------------- ---CCNCARYTNTAYAARCARACNTCNGAYGAYAARAGYAAR------------------ ------------------------------------------------------------ GTNTAYYTNCCNGGNYTNGGNTCNYTNGTNAAYAARCCNAARGARMGNCCNCARGAYACN ------CCNGGNATHGGNGCNAAY------------------------------------ ---------GARGCNATHCCNTCNAGYCCNGCNGARAARACNGTNAARTGYAAYTCNAAY GARCCNGARGAR------------AGY--------------------------------- MGNGAYGARMGNAARGTNGGNGCNTTYGGNGAYATHGARCCNCARYTNAGYGAYGGNTCN ---------------ACNYTNATGTCNGAYATHGARGAYAAYTCNGTNACNTTYYTNYTN GARGARGGNGCNGARTGYATGGAYYTNCCN------GCNGAYGARCCNCAYACNCARTCN GARAARACNCAYACNYTNAAYACNAARGAYGAYTAYTTYTTYTAYCARGCNYTNACNGGN CARCAYATHTAYYTNAGYTCNYTNAAYGCNCARTGYYTNGCNMGNGARTAYGAYTCNYTN GARGARAGYCCNGAYACNATHAARGGNACNATHGTNGCNATHGAYMGNATHTTYATGACN GARGAYGTNMGNAARMGNYTNMGNTAYYTNGGNCAYATHCCNYTNACNTGYGARTTYTAY ATHATHGARYTNAARTTYCARCCNCARACNATHAGYAARGAYACNYTNAARCAYTTYGAR GCNTCNTTYGARMGNAARMGNAARYTNMGNCARCARAARGCNAAYGARGAYAARMGNMGN GCNMGNAARTAYGARYTNGARGARMGNAARAGYTAYGGNYTNTAYCCNGARATGAARATH CCNYTNGAYAGYGARAAYCARTTYCCNTGYCCNYTNTCNGCNAGY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARTCNTCNMGNATGYTNAARYTNGARYTNACNGAYGGN CAYMGNACNATHCARGCNATHGARTAYAARCCNATHMGNGCNYTNAAYGCNGAYYTNYTN CCNGGNAGYAARGTNYTNATHAARGGNTCNGTNYTNTGYMGNAARCARGTNYTNATGYTN CARGARGAYAAYGTNTGYGTNYTNGGNGGNGARGTNGARGAYYTNGTNGTNGTNAAYAAY CCNYTNATGAAYYTNGARGCNGARATGGARMGNAAYMGNATGAAYCAYTTYGGNGAYGAY GAYGAYGARGARMGNGAYGARAARCARCARYTNGARGAYGARGARAARAARTAYYTNGGN GAYYTNGARGAY------GARGARGARYTNATHAARAARAAYAARCCNCCNACNGCNCCN TCNAARATGGTNYTNTTYTAYACNTGGATGATHGTNGCNATHYTNGTNATGGTNATHGCN GCNTCNACNTAYCARGCNAARTGYAARGGN---YTNYTNTCNGGNGGNCARCARTCNMGN GGN---GARGAYMGNAARMGNYTNYTNGAYAAYGARTTYGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TGGYTNACN GAYGCNATHYTNGTNCCNTTYYTNGARTCNAAYCCNCAYYTNAARCAYTTYGAYYTNACN GARTGYTCNAGYGTNAGYAAYGGNAGYATGCAYGCNGTNTCNYTNTAYTCNCAYAARYTN AARAARYTNGTNYTNAARGAYTGYCAYTGGYTNAAYGGNGCNGCNYTNAGYGGNATHGCN ATGACNTGYACN------GARYTNGARTAYGTNGAYYTNACNGGNTGY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYAAR ATHGTNYTNTAYAGYTAYTTYMGNAGYTCNGCNAGYTGGMGNGTNMGNATHGGNYTNGCN YTNAARGGNYTNAAYTAYGAYTAYGARCCNGTNCAYYTNGTNAARGGNCARCARAGYACN GAYGARTAYAARAARTTYAAYCCNATGGGNCARYTNCCNTCNYTNAARATHGAYGGNCAR GTNYTNACNCARTCNYTNCCNATHYTNGARTAYYTNGARGARMGNAAYCCNGARCCNGCN ATGYTNCCNAAYGAYAARGCNGGNMGNGCNAARGTNMGNGCNYTNGCNGARGTNGTNAAY AGYGGNATHCARCCNYTNCARAAYYTNTCNGTNYTNCARAARATHGGNGARACNAARATG GARTGGGCNCAYCAYTTYGTNACNAARGGNTTYACNGCNYTNGARAAYATGYTNCARGAR ACNTCNGGNAARTAYTGYTAYGGNGAYCARGTNACNYTNGCNGAYATHTGYYTNGTNCCN CARGTNGCNTCNGCNGTN---MGNTTYAAYGTNGAYYTNACNCARTTYCCNACNATHAGY MGNATHAAYAARGCNYTNGARGAYYTNCCNGCNTTYAARGTNGCNGAYTCNMGNMGNCAR CCNGAYACNCCNGARGAYATGAARATHGAR------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATGCAYCCNGCNGGNTAYCARACNGCNCAYTGYYTNCCN GCNGCNGGNGTNMGNYTNCCNYTNAAYMGNGAYGTNTAYMGNTTYAAYMGNGCNGTNCCN ATGTTYGARTCNGAYCCNTGYATHMGNCCNAAYACNGGNGARTTYATHTGYCARTCNACN AAYTGYGGNCARGGNGARATHTAYGAYTCNTCNATGCARGCNMGNGGNCAYCCNGARGAY AGYCAYGCNMGNTTY---------CARTTYCCNCCNAAYGAYCCNCARGCNCARACNGCN GAYCCNACNGCNMGNTGYMGNTGYCCNTGYGCNTCNMGNGGNCCNGTNACNGAYATGYTN CARTGYCCNTGYACNAAYATGTCNGAYMGNYTNAAYACNMGNGTNATHCARGTNACNAAY ATHGCNCCNAGYTGYACNAARGAYCARYTNMGNACNYTNTTYGGNTAYYTNGGNMGNATH AARGARYTNGARATGTTYCCNCCNGARGGNGCNGAR---GGNGTNGTNACNGCNMGNGTN GGNTAYATHGARTTYGARGAYAAYGTNACNACNGGNGTNGCNYTNCAYYTNAGYAGYACN GTNTTYATHGAYMGNGCNATHACNATHGTNCCNGTNATGGAYGGNAARATHCCNGAYGAR AGYTCNGCNYTNCARYTNACNCCNTCNGCNGTNGCNGGNATGYTNCCNGGNCARCCNACN TGGCCNGCNAAYGTNGTNTCNCARGTNACNGGNYTNGGNGCNAAYCARGTNATHATGACN AAYGAYCCNMGNYTNACNTCNYTNGGNYTNCCNCARTAYCCNCCNYTNCCNGCNACNACN GAYCCNAGYAARATHGARGARATHMGNMGNACNGTNTTYATHTCNGAYYTNGARCCNAAR GTNACNCCNGARATGYTNYTNTCNTTYTTYTCNCARACNGGNGARATHAARTAYATHMGN ATGGCNGGNGAYGARAAYGGNCCNACNMGNAAYGCNTAYATHGARTTYACNGAYCARMGN TGYATHGCNCARGCNYTNAGYTAYAAYAAYGTNGTNTTYCARGGNMGNACNGTNAGYGTN AARCAYGCNACNACNGGNATHGTNAARCCNTCNCCNAARTCNGARGCNTCNCARMGNGAR ATHGAYGAYGCNATGAARAARGTNAARGARGCNTCNAARYTNATHTCNGCNGCNGCNAAY AGYGARMGNGAYGGNTCNGCNTCNCCNTCNMGNAAR------MGNTCNAARTCNMGNGGN MGNAGYMGNTCNCAYTCNAARTCNAARMGNTCNMGNTCNMGNTCNMGN---GGNMGNMGN AARMGNAGYTCNTCNMGNACNMGNMGNMGNTCNMGNTCNMGNMGNMGNTCNCCNMGNMGN TCNMGNTCNCCNMGNMGNMGNMGNMGNTCNMGNTCNMGNGGNMGNGTNGCNCCNACNGCN CCNCCNGTNMGNMGNTCNMGNTCNMGNTCNMGNMGNMGNTCNMGNACNMGNTCNCCNGTN MGNMGNMGNMGNTCNMGNACNMGNTCNAARTCNAARCCNMGNMGNTCNMGNACNCCNCCN AARTCNTAYAGYMGNGGNMGNMGNTCN--------------------------------- ------------------------------------------------------------ ------CAYTCNMGNGTNMGNGARGAYAAYGGNAARGCNAARGGNAAY------GGNMGN TCNCCNAGYCCNGCNAARGCNAARAARMGNAGYGTNACNCCNMGNAARACNAGYMGNTCN MGNTCNCCNAGYMGNMGNAARMGNMGN------------MGNTCNACNTCNMGNAARMGN ACNTCNMGNTCNMGNAGYGCNTCNMGNCAYMGNACNMGNAARGAYAARAARMGNAGYMGN AGYMGNGAYMGNAARCAYGARAGYAGYAARAARAARAGYGGNMGNGAYAARGARGARAAR AARAARGAR---AGYTCNTCNTCNAARATHAARMGNGAYTAYGAYGARGARGARAARGGN TTYGCNAGYGARGCNAGYGARGTNGCNGARAAYAGYGAYGCNGGNGGNTCNGAYGAYTCN GCNCCNGCNCCNCCNGTNYTN---------GARAARGAYACNGAYCAYCARACNGTNGAY ATGGARATGAGYGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GGNCCNATHAARGAYCARYTNTAYGGNAARATHGCNCARAARYTNATHGARATGGCNGAY ACNTAYGGNACNAAYACNTCNGAYACNGARAGYMGNTCNYTNGARGARATHACNGAYGCN CCNYTNACNGAYYTNGARAARGARATHATHGCNTGYYTNMGNTCNGGNGGNGARAARTAY GGNAARAARATGGARGAYCARYTNGAYGCNATGAARCARGCNGTNGCNGAYGARGCNTAY GAYMGNTTYMGNACNACNATHGAYAGYTCNATGGGNCAYGARYTNAGYTGGAAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------MGNCCNYTNCCNYTN CCNCCNTCNGCNCCNCCNATGCCNGCNTCNMGNGARAARACNGTNGTNGCNYTNTAYAGY TTYGAYGCNAAYGAYGARCARGAYYTNTCNYTNACNCARGGNGARGARTAYACNGTNYTN GAYGAYAGYMGNGARCAYTGGTGGATGGCNMGNAAYGCNATGGGNCARAARGGNTAYATH CCNGCNAAYTAYGTNAARACNGTNGARGGNYTNGARAARTAYGAYTGGTAYTAYAARGAY ATHACNMGNCARMGNTGYGARGCNATHYTNMGNAAYGARGGNMGNGARGGNTGYTTYYTN GTNMGNCCNTCNGCNACNGCNAARGGNACNTAYACNYTNTCNYTNTTYACNAARGARAAY GCNGGNTCNGTNATHCAYTAYCAYGTNAARGCNAAYCARACNGAYCARTAYTAYTTYTCN GARAARCAYACNCAYGARACNATHCAYGAYYTNATHTTYTAYCAYAARCAYAAY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CCNAGYTTYAARACNACNCCNYTNATHGTNACNCCNGAR GTNAGYMGNTCNMGNATGYTNGAYACNCARACNGTNGTNTCNGCNYTNMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------CARATHTCNCAY ATGATHGCNTTYATHGAYCARGARGCNTCNGARAARGTNGARGARATHGAYYTNAARGCN GARGARGARTTYAAYATHGARAARGGNMGNYTNGTNCARCARTCNMGNGTNCARATHATH GAYTTYTAYGAYAARAARGTNAARAAYGTNGARYTNCARAARAARATHCARAAYTCNAAY ATGCARAAYAAYGCNMGNYTNGARATHYTNMGNAARAARGARGARTAYGTNAAYGARGTN ATGGARGAYGCNMGNCARAARYTNAARMGNGTNGCNATGGARAAYCCNGARGARTAYAAR MGNYTNYTNATGMGNYTNATHGTNCARGCNYTNGTNMGNYTNATGGARACNAARGTNYTN ATHMGNTGYMGNMGNGARGAYGTNCARATGGTNAARAAYGCNGTNCCNAGYYTNACNAAR GARTAYACNGARYTNYTNAARGGNAARTAYTCNYTNGARYTNGTNGTNGAYGARGAYAAR TTYYTNTCNTCNGARATHTGYGGNGGNATHGARYTNMGNGCNYTNAGYGGNAARATHGTN GTNGTNAAYACNYTNGAYGARMGNATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------YTNCARMGNGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GTNTAYATHTCNMGNACNGARAARTTYAGY GCNTGYCAYMGNYTNCAYAGYCCNGTNYTNAGYGARGARGARAAYMGNGCNATHTTYGGN AARTGYAAYAAYCCNAAYGGN--------------------------------------- ------------------------------------------------------------ ATGGCNGARGGNGAYCARCARTAYACNATHTAYGAY---GGNAAYCARCCNYTNACNYTN ACNGTNAAYAAYGTNAAYCARGGNACNGARGAYGCNCARGCNGTNCARAGYATHCARTAY ATHTCNCCNGARGGNGTNCAYGTNGCNCARYTNGAYTCNAAYGAYGTNATHCARGTNGCN CARGGNGGNGAYGGNAGYTTYCARCARACNACNACNGGNTAYCARAGYYTNCARGGNGCN GTNCARCCNCARATHATHACNAAYGCNACNTCNGTNCCNATGACNGGNGCNTCNCARCAR GGNGGNACNATHYTNCAYGCNAAYAAYYTNYTNMGNAGYGTNACNCARCARGCNCARCAR ACNGCNCARACNCARCARATHATHCARACNGCNGGNACNTCNGGNGCNGCNGCNGGNACN GCN---GCNGGNATHCCNCARATGYTNTTYYTNAAYCARGTNACNATHAAYGGNCARACN TCNTAYGTNYTNGTNGAYGCNAAYAAYAARCCNATHCARYTNCCNCARGGNATHCARGTN ATHAAYYTNCCNCAYCARCARYTNTCNGGNCARTCNATHCARATGCCNGGNAGYGAYACN GGNGAYGARCCNYTNTAYGTNAAYGCNAARCARTAYCAYMGNATHYTNAARMGNMGNCAR GCNMGNGCNAARYTNGARTCNGARGGNAARATHCCNAARGARMGNCARAARTAYYTNTAY GARTCNMGNCAYMGNCAYGCNYTNAAYMGNGCNMGNGGNAAYGGNGGNATHTTYGTNGGN CARACNGARTCNGTNGARGTNATHYTNGTNTAYGGNAARCARAARATHCCNGTNAGYYTN GAYGTNTCNMGNTCNCCNYTNGAYACNCAYTCNYTNACNGTNAAYCAYYTNTGYCARGCN GTNCAYCARTAYGTNCAYATHAARCCNGARTCNCARAARYTNATHTAYMGNGGNMGNACN YTNTTYAARAGYTTYGAYCCNGARGAYGAYAAYATGAARAARACNYTNTCNTCNTTYGGN ATGAARAAYGGNGAYMGNATHATGGTNTTYGGNAARCCNTCN---------AARGAYGAR ACNGARAGYGAYGAYMGNGARGARAARAAYYTNATGAARGTNYTNGAYCARCAYCARAAR AARATHGARGARATHTGYYTNYTNTGYAARGAYATGTTYGARAARATHGARGAYAAYCCN GGNACNGTNGARGAYTGGMGNAARCAYAARAARTTYTTYYTNTGYCARTCNGARYTNTCN YTNCARGARGTNACNMGNYTNGAYGCNACNCCNGGNGAYYTNTCNCARAGYCARGGNTAY AARATHMGNMGNAARGCNYTNGTNAAYAARYTNYTNGARAAYATGACNYTNTGYGAYAAY CARGTN---------------------------------ATGAAYGARATHATHMGNMGN YTNGTNGGNAAYTTYGAYMGNYTNGARATHGTNGTNTTYGAYGARGAYACNATHYTNAAY AARCCNGTNGARGARTGGCCNATHGTNAAYGGNYTNGTNTCNTTYTTYTCNCAYGGNTTY CCNYTNGAYAARGCNATHGCNTAYAARGARYTNMGNAAYCCNTTYATHGTNAAYGAYYTN GARATGCARTAYACNYTNCARGAYMGNMGNAARGTNTAY--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GARMGNGARATHGTNGCNCARAGYATGACNTTY YTNYTNGCNGGNTAYGARACNACNAGYGCNGTNYTNGCNTTYTTYTGYCAYGARGTNTCN AARCAYTCNGAYGTNCARGARMGNATHTTYCARGARATHAAYGCNAAYATHGGNCARAAR AAYGTNGAYTAYGARAGYATHCARGAYYTNCAYTAYTTYGAYMGNGTNTTYGAYGARGTN TGYMGNYTNTAYCCNACNGGNTCNATHATHACNMGNCARGCNGCNGARMGNMGNTGYTAY GGNGAYGTNACNATHCCNGCNGGNATGAAYATHYTNGCNAAYGTNTGGGCNYTNCAYMGN GAYCCNGCNTTYTGGGAYGARCCNGARACNTTYAARCCNGAYMGNTTYGARGAYTCNGTN GCNATHMGNAARTTYACNTAYYTNCCNTTYGGNGCNGGNCCNMGNCAYTGYATHGGNATG MGNTTYGCNACNATHGARGCNAARATHACNYTNATHAARYTNATGAARMGNTTYYTNYTN GARAARCCNGARGAYGTNTCNGAYGAYYTNGAYGTNMGNGGNGCNATHGTN--------- ---------------------------------------------------------TCN YTNGARGTNACNCCNYTNGCNGCNYTNTCNMGNCCNGTNTGYGGN---AGYMGNGGNMGN ACNYTNGTNTTYCCNGGNAGYAARAARGGNTCNGARGARTGYYTNACNTTYGTNGCNGGN GTNYTNCCNCAYGCNGTNGAYYTNYTNCAYGAY------MGN------------------ ---------------------------ATGGGNAARAARCAYAARCAYGGNAARCAY--- TCNTCNTCNAGYAGYAGYTCNTCNAGYAGYGAYTCNTCNGAYGAYGARTGGMGNCAYYTN CCNAARCAYGARAARAARYTNMGNAARAARTGGAARAARCARATGMGNAARGGNAARYTN CCNCAYGGNTCNATGCCNCCNTGGCAYGGNGGNCCNGCNTGGGCNCCNCCNATGAARGCN GGNAARAARGGNAARCCNGGNAARGCNGGNGGNTAYCCNGCNGGNGCNTAYCCNACNGGN ACNCAYCCN------------------------------------CCNCCNGCNGGNTAY CCN---GGNCARCCNGCNTAYCCNCCNACNCAYGGNTAYCCNGGN---------GCN--- GCNCCNCCNGGNGGNTAYCCNGCNGGNGGNGGNGCNCCNCCNACNGGNTAYCCN------ GGNGCNCCNCCNACNGCNTAYCCN------GGNGTNCCNCCNACNGGNTAYCCNGGNGCN ---------CCNCCNACNGCNTAY---CCN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GTNCARGARGARAARTCNAAYGCNGARYTNAARYTNCARAAY AAYCARGAYMGNTTYGAYGARYTNGARTGYGARAARGGNGARATHTCNMGNCAYGCNTCN GAYYTNGARAGYACNATHCAYGAYYTNATHGCNCARAARGARATGACNGARAARGARYTN AARGAYGARATHMGNGCNMGNATHTCNGCNGARGARMGNYTNAARGARGCNGARMGNTCN YTNAAYTGYYTNGAYCARGCNGTNAARACNCARTCNCAYMGNATHGARGAYAGYGCNAAR GARGARATGAAYGTNAGYGTNAAYAAYYTNAARAAYTTYTTYGARGAYYTNGCNGARGAR GCNAARGTNTCNTCNGAYAARCCNYTNATHATHMGNAAYGGN------------------ ---------------------------------------------------ATHTTYGCN GGNMGNATHTTYAGYAGYTAYTTYTGGGGNTGGYTNGCNGAYGTNMGNGGNMGNAARTGY GTNTTYYTNTAYAGYATHYTNYTNACNGGNATHGCNACNGCNYTNTTYGGNTTYTCNGTN AAYATHCCNATGGCNATGAGYYTNMGNTTYYTNTGYGGNYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR YTNCAYTAYTTYGAYATGAARGGNMGNGGNGARYTNATHMGNYTNYTNTTYGCNGTNGCN GGNGTNGARTAYGARGAYGTNMGNATHAARTTYTCNGAYTGGCCNGCNYTNAARGARACN ATGCCNTTYAARMGNYTNCCNGTNYTNGARATHAAYGGNAARGCNTTYGCNCARAGYACN GCNYTNTCNAARTAYYTNGCNGAYAARTTYGGNTTYTAYGGNCARACNAGYGARGAYMGN YTNGARATHGAYCARGTNACNGARYTNGTNAARGAYTTYATHTTYCAYGTNGAYMGNTCN TTYGCNGARTCNGAYCCNGARMGNAARGCNGCNYTNATGAARGARGCNGTNGARGTNCAY AGYYTNACNTAYYTNACNTTYYTNGARGCNATHATHAARAARAGYGARACNGGNYTNTTY GTNGGNTCNCARYTNAGYATHGCNGAYYTNGCNGTNTTYGAYATHYTNGAYTGGGTNGGN GAYAARAAYCCNGGNCCNYTNAARGAYTAYCCNYTNYTNCARGCNTTYAARGARAARATH TCNMGNGTNGAYMGNYTNAGYCARTAYYTN------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------MGNATHCARMGNGARYTNCAR GARATHTCNAARATHAARGAYGARAGYGGNATHGGNCARGTNATHTAYMGNGARYTNGAR GGNYTNAARGCNAARCCNCAYCARCCNYTNGAYCCNTGGAARGCNTCNMGNGCNCCNAGY GCNAARTTYGARCCNMGNTAYMGNACNMGNTTYCARTCNCCNATGTTYGCNTCNCCNTCN MGNTTYYTNGAYMGNCCNMGNTAYGCNTGGGAYGAYAGYGAYATHMGNACNTAYMGNTCN GCNTCNACNYTNGCNAAYYTN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GAYGAY YTNCAYTAYGTNTTYAGYACNAARGGNGTNCCNACNATHATHATGGCNMGNACNACNAAR YTNGAYTCNAARATGGTNTTYGAYTGGGARAARATHYTNAAYAAYGTNTCNYTNGARGAY GCNATHAGYTTYCAYCCNAARCCNACNGTNGARTAYAARTTYGGNATHGCNTTYACNAAR YTNATHGARTAYGAYGAYATHTAYGAYGAYGCNAAYATGGARGCNGCNGGNAARCAYTCN GAYCARTGGAARATHMGNAAYTTYACNGAYATHATHTGGGARACNYTNAARATGGAYAAR AARAARGAYAGYTTYACNTTYAAYACNACNGAYGAYGGNTTYGGNCCNGARATGTCNAAR AAYGGNAGYYTNTCNTTYACNTTYMGNACNCCNTCNGARGGNGGNMGNATHGGNGTNYTN CCNTCNCARAARTAYTCNGTNAAYGARACNATHTTYGARTTYGTNATGGAYAAYTTYACN CCNTCNTTYAAYCAYTCNMGNTTYGCNYTNGARATHGTNGCNATHAGYYTNGARAARAGY AARAARATGAARGTNGARACNATHAARACNATHGAYGAYGARTAYTCNCCNGGNGTNTTY YTNYTNACNAAYTGGYTNACNAAYCCNGCNGARGARTCNAARTTYGGNTTYATGCARTGG AARCCNGTNTGYTAYACNGGNTCNCCNMGNGGNMGNAARACNTCNTCNAARGTNACNAAY TAYGAYYTNATGAARYTNAAYGARGARGARATGYTNAAYTCNTCNYTNYTNYTNGCNGTN TTYGGNGARGARYTNYTNGAYGGNCARTCNGAYATHCARMGNATG---AAYGTNTCNTTY GGNYTNTTYAARGAYGGNTTYTAYYTNAARAAYAAYTAYACNGTNTGGAAYGCNGCNYTN GGNTAYGGNGARCCNCCNAARGAYGCNATHTCNATGACNGTNATHATHATHATHGCNGCN GGNYTNGGNGTNCCNGTNYTNYTNATHATHTTYGGNGGNGTNTTYACNATHTAYMGNAAY YTNAARAARAARCCN---TCNGAYTAYCARMGNATHCARGGNGAYAAYAGYATHAGYCAR TCNGARCCNGTNGTNAAYATHAARATHYTNGARTTYGTNYTNTCNATHTTYGCNTTYGCN ACNACNACNAGYCCNGARACNTCNACNACNTTYACNGTN---AARGAYTGYAAR---CCN TGGAAYAAYCARACNGGNCCNGCNTCNAARACNTTYTCNTAYAGYTAYCCNTAYGAYYTN GCNAGYGTNTGYTTYAAYYTNCCNATHTGYGARGGNGCN---AARACNGTNATHAARAGY AARTTYTGYYTNYTNGARGGNTCNGARTCNTCNGCNCARTTYTAYGTNTTYGTNGGNGTN ATHGTNTTYYTNTAYTGYYTNGCNGCNYTNGTNYTNTAYATHTTYTTYGAYGARACNTAY MGNMGNAAYTCNMGNTTYGTNGTNGCNGAYTTYGTNATHTCNTGYGTNYTNACNGTNTTY TGGATHATHTCNTCNTCNGCNTGGGCNGCNGGNYTNAAYGAYGTNAARYTNTAYACNGAY CCNGARGAYGGNGGNATHTTY---ACNAAYGTNCCNGARTGY---ACNGCNAARGGNGCN TGYTTYACNAAYAAYGGNGGNAAYTTYGCNAGYYTNAAYGTNTCNATHATHTTYGGNTTY YTNAAYTTYATHGTNTGGGTNGGNAAYYTNTGGTTYYTNTAYAARGARACNCCNTGGTTY AARGTNCARGCNMGNCCNCCNACNCARCCNYTNTGYAARGCNCAYATHGARTGYGAYTGG GARYTNCARTCNTAYGTNAARACNAARACNGARATGATHCARCARAARYTNAARGARAGY GARAAYYTNTCNGAYTTYATGAARACNTTYACNGARATHGCNACNAAYTGYYTNAAR--- GARGAYTCNACNCARAARCCNTGGATHGAYYTNAAYCARAAYATHYTNCAYCARYTNCAR AAYATHGGNTGGGARAARGTNATHAAYYTNTCNGARGAYTTYTCNTGYGTNGARATHGGN TGYTTYGAYAARGGNCARMGNCARCAYATHYTNAARGTNGTNTTYGAYAARGARAAYTCN YTNGCNCARCCNACNTGYACNACNGAYYTNCCNCARCCNTTYGAYTTYCARTGGTCNCAR ACNGCNCARYTNAARGAYYTNATHTCNCARTTYGARATHAGYYTNAAYYTNTAYCARGAR TTYTGGAAYTGYGTNGARGARATHGAYAARAAYACNTGGGTNYTNGARCCNGARCAYMGN ACNTAYGCNTGYACNTAYMGNMGNYTNGCNYTNGGNCARAAYYTNTCNYTNCAYATHATH ATHAAYTCNYTNCARCCNTCNAGYYTNCCNGARTGYMGNYTNYTNGGNTCNGARYTNATH GTNGCNCCNYTNMGNGARAARYTNAAYGTNAAYYTNCAYCAYTGGGAYYTNGGNMGNTCN YTNYTNAAYAAYYTNCARGARGTNYTNGARATHGAYTTYCCNGCNCCNTCNCAYTCNATH ATHGARGARGTNAGYGTNGARTGYGGNATHTGYTAYAGYCAYCARYTNGGNGARGARATH CCNGAYYTNGTNTGYCARTAYCCNCARTGYAGYCARGCNTTYCAYTAYACNTGYYTNTAY GARTGGYTNMGNAAYTCNTCNTGYMGNCARAGYTTYAAYTAYATHTTYGGNGARTGYCCN TTYTGYAGYAARCCNATGMGNGTNAARATH------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------GAYGAYGAYGAYGAYGTNAARAGYGGNGGNGAYGARGCNCCN MGNTCNCAR------------TCNCARGARAARGCNGCNGCNAARGCNTCNCCNGTNAAR MGNAGYCCNTCNCCNACNGARTTYATGACNGARGARGARAARGARTTYGCNYTNATGGTN AARGTNAARMGNATGYTNACNGARACNYTNYTNGCNGTNACNGAYCARGARATGAARAGY ATHGCNACNGARGTNTAYAARAARGARAARTCNAARGCNYTNAARGCNCCNGCNAARCAR YTNGCNAARTCNTCNGCNYTNGCNTCNYTNTCNAGYYTNGGNGTNGGNTAYGGNACNGAY AGYGARAAYAGYGARGCNGAYGGNCAY------AARGAYGARGAYTCNGAYACNGAYYTN GARGARCARATHMGNMGNAARAARGCNGAYTTYGCNAARMGNCARAAYATHTTYAGYGAY GCNGARGAYGAYGAR---GAYGAYGAYAARACNGCNTCNTCNGGNMGNMGNTCNGARGGN GGNAARGGNAARGAYAGYGCN---------------------------GGNAARCCNAAY GARAARAGYGAYMGNMGNMGNACNGTNGAYMGNCARGAYTCN------------------ ------------------GAYAGYMGNAGYGTNAAR------------------------ ---------------------CAYGARMGNMGN---------GARAGYAARGARAGYGGN AGYAGYGARAARAARCARAGYGGNGAYTCNAARACNAARCARGAYAAYAGYAGYAGYCAY GARAARMGNAARCAYGCNGARGARAARCCNGCNGTNAARGTNGARAARGTNYTNAARACN GARAARTCNCARAARGTNGTNAARAARGARAARMGNGARGARAARAGYAGYAGYAGYAGY AGYAGYAGYGGNAGYGGNAGYAGYAGYGGNAGYGTNAGYAGYAGYATHAGYAGYGGNAGY ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATGTAYAAYGGNATHGGNYTNCARACN GCNMGNGGNAGYGGNACNAAYGGNTAYGTNCARMGNAAYYTNGCNTTYGTNAARTCNAAR AARGAYMGNGTNGAYTAYAARAAYGARGARGAYYTNCARAARYTNGARCARTCNATHAAY MGNCARCCNAAYCARGARATHYTNGAYCAYGARMGNAARMGNAARGTNGARYTNAARTGY ATGGARATGCARGARYTNATGGARGARCARGGNTAYACNAGYAARGARGTNAAYGAYAAR GTNAAYATGTTYMGNAARATGYTNATGGCNAARGARGGNGTNTCNGAY---AGYCCNYTN GARAARGAYGARCAYGGNMGNCCNATHGCNAARGARACNCAYCARYTNGCNGARGCNAAY CARATHAARAAYGAYAARYTNAARGARGCNTTYGGNYTNGGNGARTAYGTNGAYGGNTCN GCNTTYGAYCCNAAYMGNAARGCNAARGARGARCARGCNAARGCNGTNGCNATGGCNCAR AARAARTAYAGYATGGTNAARAGYTCNGAYGARGAY---GCNGARAARGAYAGYTCNCCN GTNCCNAARAARAARAARAARAARAGYMGNCAYGARGAYACNTCNTCNCCNGARMGNAGY MGNGARAARMGNAARAARAGYAGYAARCAYAGYAARMGNGAYMGNGARATHMGNGGNYTN CARGGNGTNAAYAARCARYTNAARGTNGAYYTNCARACNGARCARGAYGCNGTNYTNCAR YTNMGNAARAARATHAAYAAYGTNGARAARCARAARYTNGARGCNGARACNMGNGCNAAY GCNGARATHTCNAGYYTNGARACNCARATGGCNAARYTNMGNTCNCARATGGARAARGGN GARGCNACNMGNCAYAAYYTNGARTAYGARYTNACNGTNAGYCARMGNGAYYTNGARAAR MGNAARCARACNACNAGYGARAARGARTCNATHTTYAARGAYACNACNGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TCNAGYGTNGARTCNACNTGYGTNTTYGGNTCNGTNTTYGTNAAYACNATG ATGACNTTYTAYATHAAYCCNGAYAAYGARCARTCNGAYTCNACNGTNAARMGNATHAAY ATHTTYTCNCARCCNGARATHYTNGAYMGNGTNCCNAGYGCNTTYYTNYTNTAYGGNACN ACNTCNYTNATHYTNAGYTGYATHGGNTTYYTNYTNACNMGNATHCCNACNACNACNACN CCNAARGAYCCNTTYGCNGAYGCNGAYATHATHCAYGAYCAYCAYGARTAYTAYACNTCN CARGGNYTNAARGARCARGTNAGYAARTTYTAY---CAYGARYTNGCNGCNGCNAGYMGN CAYAARACNYTNTCNGARACNCAYMGNGTNGCNGCNACNATHAARYTNGAYTTYAARTTY CCNTTYTAYGGNCAYYTNGTNGAYCAYGTNACNATHGCNACNGGNGGNTTYGTNTAYATG AGYCCNTTYYTNCAYCARTGGYTNACNGCNACNCARTAYATHGCNCCNYTNATGGCNAAY TTYGAYCCNTCNGTNAGYTCNGGNTCNCAYATHTAYTAYYTNAGYGARGCNGARATGTTY ACNGTNGARTGGAARGARGTNAARYTNAARGAYCARCARGARTTYGGNAAYTTYACNTTY CARYTNACNYTNCAYAARAAYGGNAGYATHGCNTTYGTNTAYAARAAYGTNCCNGTNCAY ATHAAYCARATHTCNGAYAARAAYCAYCCNGTNAARGTNGGNYTNTCNGAYGCNTAYTAY AAYGAYACNTAYYTNCCNMGNTTYMGNGTNTAYMGNMGNACNATHTAYGARTAYCAYCAR GTNGTNGTNGAYGARACNATGGCNMGNACNGGNGCNGTNGTNTTYATGAAYCCNGTNCCN ACNTGYAAYACNYTNACNGAYTGYGAYAGYTGYGTNMGNCAYGARAAYGTNTCNTTYGAY TGYAARTGGTGYAAYACNATHGGNATHTGYTCNGAYGGNYTNGAYTGGTAYMGNCARCAY TGGGAYAARAAYAARTGYCCNGCNCARAGYYTNAAYAAYACNAAYGARTGYGTNAAYYTN AARCCNCCNTCNAARCCNATHGTNAAYCCNATHGTNCCNYTNGGNCCNCARAARCAYAAR TGYACNGAYGGNAAYTGYGGNAARGGNTCNAAYACNCCNGTNGCNGTNGTNATHGTN--- GTNGTNATHYTNATHYTNATHYTNGTNGGNGGNGTNGGNGGNTGGACNTAYTAYGCNTAY ACNCAYCCNACNTCNAARTCNGGNATGTGGYTNATGGARCAYMGNCCNAGYCARATHAAR GCNAARATHAARTTYTGGAARAGYAGYTCNAGYAAYGGNGCNAARTAYAARACNGAYACN GARGCNMGNGARACNGTNAARYTNAAYTCNAARYTNGCNGARGARYTNGGNGCNGCNMGN AARGARATHGARATHYTNAARGGNMGNYTNAARGARTTYGARATGAAYAGYYTNGCNMGN CAYTAYAGYCARYTNCARTAY--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TGYCCN ACNYTNCARGGNAARCCNAARYTNTTYTTYATHCARGCNTGYCARGGNCAYATHAAYCAR ACNGGNTTYCARACNAGYMGNGARGAYAGYGAYAAYTAYGGNGARACNCCNTCNYTNYTN CCNAAYGARGCNGAYNNNYTNATHGGNTAYNNNACNNNNCCNGGNNNNGTNTCNTAYMGN NNNNNNNNNNNNGGNTCNTGGTAYATHNNNNNNYTNGTNNNNATGYTNGANNNNTAYNNN GAYMGNNNNGAYYTNYTNAGYATHATGNNNNNNGTNAAYNNNGARGTNNNNAARAARGGN CAYYTNNNNGCNAGYGCNATGATHGARGGNGGNATHNNNAARCARNNNCCNNNNCCNNNN NNNACNYTNMGN------------------------------------------------ ------------------------AARAAYGAYGTNAARATGTTYAAYYTNTTYTGYCCN YTNAGYGGNATHGAYCARGARGTNGGNTAYTCNATHTTYAARATGTTYGGNTGGCCNYTN GTNGCNGGNGGNTTYGCNAAYCAYMGNTTYYTNMGNGAYTCNCARGGNGCNTTYCAYAGY ACNGAYCARTCNTGYATHATHGGNGGNYTNTCNATHGCNGGNGTNAAYGTNCARGTNGCN TCNGTNGTNYTNMGNAGYCAYATHCARATGGARGARGARGTNGAYAARGTNGTNAARAAY YTNGTNGGNTAYAAYTTYCCNYTNGARAAYAGYTTYGCNTTYATGTAYGCNTGYATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GAYYTNMGNMGNAARMGNGTNGARGTNTCNGCNTGGYTN TCNGAYGTNYTNGGNCCNGARTCNGTNCCNGAYTTYGARATHAAYGCNCARACNGTNGAR YTNYTNCAYCARYTNTCNGGNATHAGYMGNTTYAAYGARGGNAAYGCNYTNYTNTGYYTN GARGAYYTNCARAARAARGCNGARGARTAYAAYGCNGAYGCNCARMGNGTNGGNTCNGTN YTNMGNAARYTNATGYTNGGNCARGCNAGYTTYTCNCARACNTCNYTNGCNTGYYTNCAR GCNYTNGCNCARACNGGNGCNGTNYTNAAYGTNMGNGAYCCNTCNGAYACNAGYTAYGTN YTNTGYYTNCARGAYYTNCAYTCNMGNGTNAAYGARGTNTTYGARAAYGTNYTNGTNCAR GGNAARGAYACNCAYMGNCARTCNMGNAARATGCARGAYGTNYTNATHAARCAYAGYYTN YTNCARMGNGCNYTNGARGCNGTNGARAARMGNTCNACNAARGAYGCNGCNCARAAYGTN GARMGNAARGARGARACNGTNYTNYTNCARMGNAARTCNGARGAYAAYGARACNAARATH GCNAARTGGGARATGCARYTNGCNAARACNGGNGTNGAYGARGCNGAYCAYCAYGCNGGN YTNGTNAARAARGGNGARAARYTNGAYAGYYTNGARAAYAARYTNAAYCCNYTNAARGCN GARYTNCARTCNTAYACNAGYYTNCCNCCNGAYCCNGTNGARGCNAARGTNAARATHGAR CARYTNAARMGNAARYTNTAYCARYTNCARGCNCARATGACNGARTCNGTNAAYATHGCN YTNACN------------------------------------------------------ ---------------------------------GGNGAYTGYCCNAAYACNGGNAGYAAR GAYAAYTTYGAYGTNAAYCARTAYYTNGGNAARTGGTAYGARYTNGARMGNTTYAAYGCN TGGTTYGARATHGGNGTNGTNTGYGGNAGYGCNCARTAYGGNYTNAAYGARGAYGGNAGY ATHAGYGTNGTNAAYGGNGGNMGNMGNGAYYTNAARATHTTYGGNTAYACNGTNTCNAGY GARCCNACNTCNATHACNGGNAARGCNACNATHCCNGAYGCNTCNMGNCCNTCNGARYTN MGNGTNTCNTTYTCNAGYTTYGAY---CCNGGNACNGGNCCNGCNAAYTAYTTYGTNGTN GAYACNGAYTAYACNGGNTAYGTNGTNGTNTTYTCNTGYACNGAYYTNCCNGGN---CCN YTNAGYATHCARTAYGCNTGGATHATGACNMGNGTNMGNGGNGCNACNCCNCCNACNYTN GCNGCNATHAARTCNAAYYTNCARTCNAARGGNGTNGAYYTNAGYAARTTYAAYGARGTN GAYCAR---------GARGAYGGNGAYACNGCNGTNTAYAARACNGCNTAYGAYAAYGAR TAYTAYGGNGARYTNGAYGGNGAYGTNGCNTTYGTNGTNCCNGARCARCCNYTNGAYAAR GARGAYAARAARGAYGTNGAYAARAARAARAARAARAARAARAARAARAARTGGYTNTCN ATHTGYYTNACNAAYTGYAARTAYGAYGTNGTNMGNMGNACNTCNMGNAARTTYGGNTTY AARGARGTNTCNGAYGAYGARGAYTGGACNYTNTAYTGGACNGAYTTYTCNGTNGCNYTN GARMGNGTNATGGAYATGAARAAYTAYCARAARATHAAYCAYTTYCCNGGNATGAAYGAR ATHTGYMGNAARGAYYTNYTNGCNMGNAAYYTNAAYMGNATGCARAARACNTAYCCNAAR GARTAYAAYGTNTTYCCNAARACNTGGTGYYTNCCNGCNGAYTAYGGNGAYTTYCARGCN TAYACNMGNCARAARAARAAYAARACNTAYATHYTNAARCCNGGNTCNGGNTGYCARGGN AARGGNATHTGGGTNACNAARAAYCCNAARGARATHAARCCNCAYGARCAYATGATHTGY CARGTNTAYATGAAYAARCCNTTYYTNATHGAYGGNTTYAARTTYGAYYTNMGNATHTAY ACNYTNGTNACNTCNTGYGAYCCNYTNMGNATHTTYGTNTTYAARGAYGGNYTNGCNMGN TTYGCNACNAAYAARTAYTGYGARCCNAAYCAYACNAAYACNGAYAAYGTNTTYATGCAY YTNACNAAYTAYGCNATHAAYAARCAYAGYGARGAYTTYATHMGNGAYGAYGTNGCNGGN AGYAARMGNMGNATHAGYACNATHAAYMGNTAYYTNAAYGARAARGGNCAYGAYGTNGAR AARATGTGGGCNGAYATHGAYGAYGTNATHATHAARACNGTNATHTCNGCNCAYTCNGTN YTNAARCAYAAYTAYMGNTCNTGYTTYCCNAAYCAYATHMGNGGNTCNGCNTGYTTYGAR ATHYTNGGNATHGAYATHYTNYTNGAYAARAARYTNAARCCNAGYATHYTNGARGTNAAY CAYTCNCCNAGYTTYACNACNGAYGCNGAYYTNGAYMGNGARATHAARGGNACNYTNATH TAYGAYACNYTNMGNYTNATHAAYTTYGGNGCNGTNGAYMGNMGNAARTGYYTNGARGAY GARMGNAARMGNATHAARGAYMGNYTNYTNGGNAARTAYGTNAARAARGAYACNAARGAR GARATHGARGCNGCNCARACNCARTTYATHGARGARYTNGARTGYTAYGARAAYACNCAY YTNGGNAAYTAYCAYMGNATHTTYCCNGTNCCNGGNTGYGARAARTAYGAYAARTAYTTY CAYAGYAGYGGNACNYTNTTYCARGARACNGCNGCNTTYAARGCNMGNCARGARYTNGCN MGNCARCARMGNGARGARYTNYTNMGNAARAARGARAARAAYGARATGATGYTNAARGGN AARCCNMGNAARGAYAGYATGMGNCCNGARAGYCCNGGNMGNAARMGNMGNYTNGGNCAR MGNCCNCCNYTNCCNYTNMGNCAYYTNAAYCARMGNCARCARGAYGTNMGNGARGCNGAR CCNYTNAAYACNYTNAARCCNCARGAYATHGTNGARGAYGARGARYTNGARMGNYTNTCN GGNYTNYTNCARMGNGAYAAYYTNGTNMGNGGNYTNGGNATHGTNGARCAYGTNTAYMGN YTNYTNCAYTGYACNCCNGGNACNATGGGNGTNGTNMGNTCNGARCARMGNCCNGGNCAR GCNGGNYTNGGNCAYGGNCAYACNYTNGGNMGNATHMGNMGNGTNGTNGGNGGNMGNAAR ATGGCNATGGGNGCNTGGCCNTGGYTNGTNTCNYTNAAYTTYAARGARCAYCAYGCNTAY YTNGAYYTNCARGGNYTNGAYCAYYTNTGYGGNGCNACNYTNATHCAYCCNTAYTGGYTN YTNACNGCNGCNCAYTGYGTNCAYGCNGGNTCNGGNAGY---GGNYTNGAYGTNCCNGGN AAYTGGGARGCNGTNYTNGGNGARTAYAAYMGNMGNGTNGARGARGARACNGARCARAAR ATHCCNGTNGARCARATHTAYGTNTTYCCNGAYTAYGTNYTNTAYCCNAAYATHACNGGN GAYYTNGCNYTNYTNAARYTNAGYMGNCCNGCNACNGARACNAGYGCNGTNMGNGCNYTN CCNYTNGAYACNYTNMGNTCNATHCCNGAYGCNTCNGARTGYCARGCNGCNGGNTGGGGN CARCAYACNCCNAAYGAYAGYGAYCCNCCNCARTAYGGNAAYGGNACNATGGTNCCNCAY ATHGTNACNYTNCAYAARGTNTCNGARGCNGAYTGYMGNGCNGCNTAYYTNGGNCAYTGG CCNYTNGTNGAYGAYTAYGTNTGYTGYTTYCAYTCNGCNYTNMGNAARGAYACNTGYATH GGNGAYTCNGGNGGNCCNYTNGTNTGYMGNAAYAAYGARGGNAAYCCNGTNYTNACNGGN ATHGTNTCNGTNGGNCARGGNTGYGCNYTNGARGAYTTYCCNGGNATHTAYACNMGNGTN GGNGCNTAYMGNGAYTGGATHYTNAGYACNATG--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARATHCARGAR AARAAYATHMGNYTNTGGCAYGCNTGGCARGAYCCNAARGAYCAYMGNCCNAAYGAYTGG ACNTTYCCNGGNGARACNATHAARMGNGTNAGYYTNTAYAARMGNGAYGCNMGNGCNATH TTYYTNTAYGTN---TGYAGYMGNCARAARCCNYTNMGNTTYYTNATHCARGGNYTNGAY GCNGCNGGNAARACNAGYYTNYTNTAYAARATGAARYTNGGNGARATHGTNACNACNATH CCNACNATHGGNTTYAAYGTNGARACNGTN---AAYTTYAARCAYATGGARTTYACNTGY TGGGAYGTNGGNGGNMGNTGYAARATGMGNCCNYTNTTYMGNCAYTAYTAYCCNAAYACN GAYGGNYTNGTNTAYGTNGTNGAYAGYCAYGAYAARGARMGNYTNGAYGAYGCNYTNGAY GARYTNACNMGNTAYGTNYTNGAYAAYGARGARCARCARGGNACNATHGTNATGGTNGTN GCNAAYAARCARGAYYTNTGYGGNGCNYTNAGYCCNGARCARATHGARTAYMGNYTNGAR MGNAARYTNAARAARGGNYTNGAYATGTCNGTNTTYGTNGTNGGNTGYAGYGTNACNACN GGNGAR------GGNGTNTGGGARGCNTTYTCNYTNTTYACNGAYYTNATHAARTCNAAR MGN--------------------------------------------------------- ------ACNATGAAYAAYTTYGGNACNGGNYTNATH------------------------ ------------------------ATHTGYGAYTCNTGYTGYGTNGAYGGNGARTCNTGY TGYTAYGAYGAYGAYGAYTAYTAYTAYACNTGGAAYATHTGGAAYATGTGGTAYTTYTGG TTYATHATHATHTTYGTNYTNYTNTCNTGYTTYGGNGGNTGYGGNTAYTGGMGNMGNMGN CARGTNYTNYTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------AGYGGNYTNATH GGNMGNAGYTTYGCNATGATHTTYGCNAGYGCNGGNTAYGAYGTNACNGTNTAYGAYYTN GARTCNGARCARACNACNGCNGCNAARGCNGAYATHYTNAARCARYTNGCNACNYTNGAR AARGARAARYTNYTNMGNGGNAARYTNTCNAARGAYGARCARTAYAGYAARATHAARACN ACNGARAAYYTNGARGARTGYGTNCARTCNGCNTTYTTYATHCARGARTGYGTNCCNGAR CARYTNGAYATHAARMGNGCNGTNTGGTCNAARYTNGAYAARATGGTNGAYCCNCARGCN ATHYTNTCNACNTCNACNAGYGCNYTNYTNCCNTCNAARATHTCNGAYGGNATGACNCAY AARAAYMGNTTYATHGTNTGYCAYCCNACNAAYCCNCCNTAYTAYGCNCCNGCNACNGAR GTNGTNCCNGCNCARTGGACNGAYCCNGARGTNGTNACNGARACNATGMGNYTNYTNMGN GARGTNGGNCARGTNCCNATHYTNGTNAARAARGARGTNGAYGGNTTYGTNYTNAAYMGN ATHCARTAYGCNATHYTNGGNGARGCNTAYMGNYTNATHGARGAYGGNGTNGTNAGYCCN GARGAYGTNGAYYTNATHATGTCNCARGGNYTNGGNATGMGNTAYGCNTTYATGGGNCCN TGGGARACNGCNTAYYTNAAYGCNGARGGNATGTAYAAYTAYAAYGARMGNTAYGCNGAY ATGATHYTNAAYATHCARMGNAGYTTYMGNCCNGCNGARMGNATGGGNGGNGARACNYTN MGNGCNATHCARGARGAYATGGARMGNGTNGCNGGNCCNGTNGARGAYATHCARAAYMGN MGNGCNTGGMGNGAYMGNMGNYTNGTNGCNYTNGCNAARYTNAARGCNGARATGGAY--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TAYCCNATGAAYGTNCARAAYATHAAYTGGMGNCARGARYTNYTNGARYTN CAYGCNATGAAYGTNMGNATHTAYGGNATHCARGTNCARAAYGARYTNACNAGYACNCAR TTYTTYGAYCARYTNACNACNGTNACNGAYGGNCARCAYYTNCAYYTNAAYAAYATGGAR MGNATHTGYAAYATHATHATGGGNATHTGYTAYMGNGARCARGGNCCNGARATGYTNAAR AAYTTYGARGCNGARGTNMGNAGYCARGARCCNGARACNTTYGAYCCNGAYYTNGARTCN ATGTTYGGNACNYTNMGNAARGARATH--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------CAYAGY CAYCAYTTYTAYCCNACNTTYAARACNYTNAGYGAYGCNYTNGTNTAYATHCCNATHGAY GAYMGNAGYAARCAYCARMGNTTYATGAARMGNMGNMGNAARMGNAARCCNGARCCNGCN CARGCNGAYCARTAYTTYTTYCAYGARTAYTGGTTYACNCAYAAYGARYTNAAYATHGAR GAYTTYYTNAARCARAARGARYTNGAYYTNAARYTNMGNGTNCARGARGCNAARGARAAR GGNGARYTNTAYGARTGYTGYTGYTGYTAYGAYGAYGARTGYYTNTTYGARGAYYTNGCN AAYTGYCCNGARGGNCAYYTNTTYTGYAARGTNTGYGTNGTNMGNTCNACNGARGCNGCN TTYGGNGARATGAARACNMGNTTYCCNTGYATHACNGGNGAYTGYGAYCARGARYTNCCN YTNAGYACNYTNCARMGNATHGTNCCNGCNAARYTNTTYTCNAARATHGTNTGYMGNATH CARGARGARGARGTNYTNAAYGCNGGNATHGCNGAYYTNGTNACNTGYCCNTTYTGYCCN TTYGCNACNGTNATGCCNAAYCCNGAYGAYAARGTNYTNAARTGYYTNAAYCCNGARTGY YTNAARGAYTCNTGYMGNYTNTGYMGNGARGARAGYCAYATHCCNYTNAARTGYAAYGAR GTNGARAGYMGNGCNGGNACNAARATGMGNACNTAYATHGARAAYAARGTNGCNGARGCN GTNATGMGNAARTGYCAYAARTGYGGNAARAARTTYYTNAARGAYAGYGGNTGYAAYATG ATGACNTGYATHTGYGGNGCNMGNAGYTGYTAYTTYTGYAARGCNCARGAYATHGARTAY AAYCAYTTYGARGGNGAYMGNAAYTGYAGYCARACNGAYCCNAAYGTNATHCAYGARMGN GAYATGAARGARGCNGCNCAYAGYGCNYTNCARGARTAYATHYTNGARCAYCCNGARGCN GCNGGNGTNGARTGGATHACNTGGAGYMGNAGYGTNATGYTNACNMGNGGNYTNMGNCAR GARGARGCNGCNGARACNGARCCNGARGARGCNGARGCNGCNCCNAARMGNAARGTNGTN GAYGCNGARACNAGYATGMGNTAYYTNGAYAGYCARGCNTTYGTNGARGGNTAYGGNGAY AARCCNGTNTGGTTYCAYTAYMGNMGNAAYTTYAARGGNAAYATHATGCCNCCNACNMGN AARMGNTGYATHMGNAARGGNGARATHACNACNTCNAGYCCNTGYCCNGTNTGYMGNGAY GARTAYYTNATHYTNGAYGCNAARAAYACNAARYTNYTNGARCARTTYATHTCNCCNCAY ACNGGNGAYATHYTNGAYTCNATGAARACNGGNYTNTGYCARCAYCARCARGGNACNYTN ATGGTNGARGTNATGAARGCNTAYGAYCARGGNTAYYTNGARATGAARGTNCCNTTYMGN ACNTAYAAYTAYGAYGAYTAYAARAGY---------------TGYTCNATGGAYMGNGAR YTNATGYTNTCNGCNGAYGTNAARGARCARACNAAYCCNGTNGCNAGYYTNTAYYTNTAY GGNYTNACNAGYCARCCNGTNGAYCAYGARATHAAYGGNCAYMGNAARCAYGCNTCNTCN GAYGCNGAYMGNTCNCCNGAYATHGAYAAYGAYAGYGAYGAYGAR---------GARTTY AAYGAYTAYTCNTCNAAYGARGAR---AGYGAYAGYGAR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------CCN TTYCARGAYYTNGTNYTNGCNGAYTCNTCNTTYYTNGARGAYGTNCCNGGNMGNACNAAR TGYGTNCARTGYCARAARTCNMGNAARTAYTAYTGYTAYGGNTGYTGYGTNGCNYTNCCN CAYYTNGCNGAYAARYTNCCNAARGTNAARYTNCCNYTNAARGTNGAYATHATHAARCAY CCNGGNGARYTNGAYGGNAARAGYACNGCNCCNCAYGCNTCNATHYTNGCNCCNGAYAAR ------------------------------------------------GTNATHATHYTN TTYCCNGGNCARCAYTCNATHACNATGGGNGARYTNTGYTCNMGNGTNAARGARYTNTCN CAYGGNAAYGARTGYCARACNGAYCARATHGAYGARGCNAARAGYYTNCCNTCNAARTCN AARACNTCNCCNGARGTNTGYTCNGARCARACNTCNATHTCNAARGAYAAYACNGTNGAY GARACNACNAARAGYATGCCNTCNCARACNGARAARAARGTNGCNACNCCNAGYGARGAR AAYYTNTCNCAYACNCAYACNGAYTCNGAYGCNGCNAAYGTNYTNACNAAYACNCARACN AGYYTNGARCCNGGNACNAARMGNAARMGNTCNGTNAAYGARGARGARAARGARGAYTCN GTNAARAGYCAYAARACNGARMGNACNYTN---AARGAYGTNCCNTTYGARAARGTNATH TTYATHGAYTGYACNTGGCAYCARACNCAYACNATHGTNAAYGAYGARMGNYTNAARGGN YTNACNAARGTNGARYTNAARTCNCAYYTNGGNCAYTTYTGGMGNACNCARGARGGNATG CCNGAYACNTAYYTNGCNACNATHGARGCNATHTAYTAYTTYTTYAARGARTTYCAYACN ATHTTYATHGAYCCNGTNTAYAARAAYGARTAYGAYAAYYTNYTNTTYTTYTTYTAYGTN ATGTAYAAYAARATHAAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GTNATHGGNAAYGTNATHAAYTGGTCNTTYGCNYTNTAYGGNGCNATHCAR CARCCNTCNAAYTTYGCNAGYTAYYTNYTNGCNATHTTYATHGGNAAYYTNYTNYTNTAY TGYYTNTTYTAYATHTTYATGAARYTNYTNAGYGGNGARMGNATHGGNYTNYTNGTNYTN ACNGTNATGYTNACNAGYYTNGTNACNTGGTCNTGYTCNYTNTAYTTYTTYTTYCARCAY YTNACNACNTGGCARAARACNCCNTCNGGNTCNMGNGARGGNAAYAARGAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ---------GAYTTYMGNGCNGARGCNGCNTCNGTNGTNCCNGTNGTNGTNGARGARCAR CARGCNGCNAARACNGAYGGNMGNAGYAGYGCNGARCCNACNGARAAYGGNGARTTYMGN GGNGARGAYMGNTCNGARATHTCNCCNCCNGARGGNACNGARGAYAGYMGNGGNCARGGN CARTGGAARACNCARGARCARCARTAYATHGCNTCNGCNGTNYTNGCNCAYAARAGYGAR ------------ACNGARGCNATGCARGAR------------------------------ ------------------------------------------------------------ ---------------------------------------------YTNCARGGNGARMGN GAYCARYTNYTN------GARGAYCARCARGCNATGAARATHAARGARYTNCARGARMGN YTNGCNGTNYTNGCNMGNGARAAYGAYGARAARGAYCARCARATHCAYMGNYTNAAYGAR GARYTNAARATGGCNGGNACNMGNYTNAARGAYACNGARMGNAARYTNGAYYTNTCNGAR GCNAAYAAYGCNTCNAAYTCNGAYGCNCCNAARTCNAARACNTGYGCNATHATG------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------CARYTNTCNACNTTYAARAGYGAYYTNAGY YTNGAYAARYTNTAYCCNACNTCNAAYCCNGAYTAYYTNMGNAGYMGNCAYAAYGCNGTN CARACNGAYCARACNYTNGARACNTTYTCNGGNCAYATHCCNACNGARCARYTNGARATH ACNCAYAGYMGNAGYAGYGGNCCNGGNGGNCARAAYGTNAAYAARGTNAAYAGYAARGTN GARATGMGNTTYCAYATHGAYTCNGCNTCNTGGATHCCNGAYTGGATHAARCCNMGNYTN ACNGAYCARGARCARAAYMGNGTNACNAARGARGGNTTYYTNGTNATHAARTCNGCNATG ACNMGNAARCARYTNYTNAAYCARGCNGAYTGYYTNAAYAARYTNMGNACNATGATHTAY CARGCNTCNGTNYTNCCNGARGARCCNACNGARGARGARATGAARAARAARGARACNMGN ATGMGNAARGCNAARAAYGARGTNYTNMGNGARAARAARAAYMGNTCNYTNYTNAARAAR TCNMGNTCNAAYCCNGARYTNTCNTCNCARACNATHAGYCARYTNMGNTAYAAYCCNTAY MGNAARTCNTCNYTNGCNTCNGCNTCNGARGAYGGNGTNGTNTCNTTYTGGGAYACNAAY ACNMGNAGYYTNGTNCAYGCNTTYAARTCNGAYCAYCARGCNCCNGCNACNGAYYTNGCN TTYTCNCCNGTNAAYGAYCARYTNATGGTNTCNGTNGGNYTNGAYAARMGNYTNGTNYTN TAYGAYGTNCARGGNGARAARTCNATHAARACNATHGTNGCNGAYTAYCCNYTNACNTCN YTNGAYATGCARGAYGGNAGYATGGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GAYATHCAYTTYGARYTNCAYGARCCNGARACNAARYTNYTNAGY GAYGTNGARCAYGAYGARACNGARYTNMGNTCNGARGCNAARGCNGTNAARYTNGARACN GGNGGNAGYYTNTAYAGYAGYACNGARTCNATHAAYAARGTNGCNACNGAYGCNAARGAR ATHCARGTNGGNGARATGGARGTNGAYGARGAYATHAAYGTNTCNCCNTAYYTNAARACN YTNATGGARGAYAGYAAYACNTCNGAYYTNYTNYTNTCNATHATHGAYYTNAARAAYGCN GTNATHGGNAGYAAYMGNGARAARACNAARGTNATHCARCARGGNYTNGTNCCNMGNYTN YTNCAYTGGATHGARGAYAARTCNTGYCCNYTNGAYYTNCARACNGARTCNGCNATHGTN YTNGGNAGYYTNGCNAARGGNGGNAGYGAYACNGTNGAYGCNYTNGTNCARGCNAARGCN GTNCCNGTNYTNYTNAARGCNATGGAYACNAGYAAYYTNAARTAYAAYGARGCNYTNYTN MGNTGYYTNMGNTCNATHTTYATGGARGAYACNGAYGGNATHCCNTAYYTNTAYGARGAR AGYGGNTGYGGNTCNCCNTAYATHTCNACNTTYYTNGTNATGACNCARCARTCNACNGTN TGYCARGARTGYGTNACNAAYATHYTNATGTGYTGYTGYAARACNMGNGAYCAYCARATG TGYYTNYTNGAYAGYCARGCNATHTCNATHYTNTCNCCNYTNYTN---CARTCNAARCAR TAYAARATHCARATGCCNACNYTNMGNTTYTTYGCNAARATGTGYTAYAARAAYGARGAR GTNTGYGCNGCNATHGTNAARGAYAAYAARYTNGTNGAYACNTTYGTNGGNYTNATGAGY MGNGAYAARCCNACNGARATGCARATGGCNGCNGCNGARATGYTNACNAAYYTNCAYMGN TGYGGNGTNATHCCNTCNAGYGAYTTYATHATHAGYMGNAARACNATGGGNACNYTNGTN MGNATGTGYATGMGNGAYMGNACNGTNCARGARAAYGTNMGNGGNGCNGARGTNYTNGCN TAYYTNGTNGARATHGAYCCNGAYYTNCARGTNACNGCNAGYTAYACNTTYCAYYTNATH AGYGCNYTNTCNACNTGYYTNCAYTTYCARAAYTCNAGYAARMGNTCNCCNTCNGGNAAY AARGARGTNGAYTGGGCNAGYGARATGMGNMGNGCNGCNTTYYTNGCNTTYGCNTCNATH AGYGCNAAYGAYGARGARATHMGNGARAARGTNATHAARGCNGAYGGNATGATGGAYCAR ATHCARTCNTCNYTNACNAGYGGNCARGARMGNGARGTNGCNGCNAGYYTNMGNTGYYTN CARTCNYTNACNMGNTCNGTNCARCARATHMGNACNATHYTNCAYGAYAAYACNATGTGG AARCCNYTNYTNGARAARGTNMGNTCNGGN---------------AAYMGNGARATHATG GTNYTNGCNATGTCNTGYYTNTGYAAYYTNGTNYTNGARTTYTCNCCNAGYAARGARGCN YTNGTNGAYAAYCAYGCNGTNGARGTNYTNTGYGARYTNTGYCAYAGYGARGAYAAYATH GTNMGNYTNAAYGCNACNTGGGGNATHATGTCNATGTCNTAYTGYGCNTCNGARGARYTN MGNATHAAYATHATHAAYAARATGGGNAARGAYACNATHGTNAARMGNATHCARGAYCCN ATHYTNYTNATHMGNGARAARGCNYTNTGYYTNGTNMGNAAYYTNYTNACNGGNAARATG TAYATHGAYAAYACNGTNAARAAYYTNGGNAAYGARGTNATHGARGCNATHTTYAARATH YTNGCNGAYCCNGAYATGCCNACNAAYATHATHACNCARGCNYTNTGYGCNYTNAGYAAY ATGGCNGAYGGNCCNTCNTGYAARACNTAYATGATHGGNAARACNGAYGARATHACNTCN GTNGTNAARTAYYTNCARTAYACNGAYACNGAYYTNCARYTNCCNGCNATHCARTTYGTN AGYAAYYTNGTNGAYACNAGYGAYGAYGAYTAYGGNYTNTTYCCNGGNGCNGGNTCNTAY CARMGNATGYTNCARYTNAARACNYTNGGNGTNCARACNYTNYTNGARGGNYTNGTNGGN ACNGGNATGGARGARGTNGARYTNMGNGCNCARCARGCNYTNAARTAYTTYGCN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CCNTCNTCNTCNCCNYTNYTNAAYCARAGY---CCNCCNCCNACN YTNACNCARCAYGGNGAYGCNAARGCNCCNMGNGGNAARGGNMGNGGNMGNGGNMGNGGN MGNGGNMGNGGNGTNGGNGGNCARGGNGTNGTNCCNGGN---GAYAARTCNCCNMGNCCN MGNACNTGGTCNGGNGGNGAYGAYMGNTTYGTNGARTGYCARAARGARATGYTNYTNGTN AARTTYGAYAAYACNGCNGGNGAYAAYACNGTNGARGTNGARTAYGARAAYGGNGCNCCN YTNTCNCCNACNCCNTCNTCNAARTCNTCNGGNTCNACNCCNGGNMGNGGNCCNACNGGN MGNACNCCNAAYCARGCNGGNAAYTCNAGYMGNCCNAARGCNGGNGGNGGNAARCARCAY ---AAYTCNAARACNGAYAARTAYCCNAARGGNGGNMGNATHCCNGGNGGNGGNGGNCAR GCN---------------GAYTGGGAYGGNCAYAAYACNAAYACNGCNAAYCAYMGNCAY TCNTAYGAYGGNTAYAARGTNMGNACNYTNTCNCAYTCNCARAGYCAYGGNGAYAGYGAR GARTGGGARGAYTGYACNGGNTCNTCNGGNGTNCCNGAYGAYGAY---------ATGATG ATGGAYATHAAYCARAAYYTNMGNYTNGARTGYCCNYTNAAYCCNGAYGCNCCNGARTTY YTNCCNATHTCNCCNGARTAYYTNAARACNCCNCCNGGNCAYCARAARGTNYTNAAYTGG CARGGNAARAAYAAYAGYTCNTCNTCNCCN------------------------------ ---------------AARTCNAAYCCNAGYCARCCNTCNYTNTCNACNCCNTCNCCNMGN GARATHAAYCAYGAYTCNTCNTTYTCNTCNGTNGGNTCNTCNGCNTCNACNMGNGCNAAR AARCAYMGNGARGARATGGAYACNATGCCNGAYGCNGAYGARCCNATGCCNCCNCCNTTY YTNYTNGAYGAYGCNGCNCARATGGCNCAYGGNAGYGARGARAARGARGARAAYGGNGAR GAR------------------GARGARGARAARGARAAYGARGAYGGNGARGARMGNTTY GARGAYTCNGTNGARGTNGCNCCNGAR---------------------------MGNCCN TGYAARGARCAYACNTTYYTNACNGAYGTNGCNGAYGTNMGNGARATGGARCAYGGNYTN YTNCARYTNYTNGARGAYTTYCAYTCNGGNAARYTNCARGCNTTYGGNCARGAYTGYACN TTYGAYAARATGGAYATGGTNMGNGARCARCARGARAARYTN------------------ ------------------------------------------------------------ ---------------------------------TGYAGYATGGTNGTNATGAGYAAYYTN AGYGTNACNATHAARGTNATGTGYGCNYTNYTNTCNTGYGCNAAYGTNGTNACNCCNGAR TAYYTNACNGTNTTYYTNGARGCNGCNAARAARGARGCNAARCCNGAYCCNTCNGAYTTY YTNCCNCCNYTNGCNGARCARATHAAYCCNGAYGARGTNTCNTTYAGYGCNGAYCCNAGY MGNCARAGYYTNTTYCARGGNAARATGTTYATHTTYYTNACNTCNAARCARTTYAARAAR YTNAAYYTNGCNATHGARYTNGGNGGNGGNATGCCNTTYYTNATGGARGARGGNACNGAY GAYGAYGAYAGYGTNYTNATHACNCCNGGNACNTGYGTNATGGARTGYAGYTCNGARAAY TCNCARCARYTNTCNCARAAYGCNCARGARTGGATHTCNCAYGTNYTNGAYTAYYTNCAR AARAAYAARAARMGNYTNATHCCNGARGCNGARYTNGGNTTYGCNGCNYTNCAYAGYTCN ACNGARAARTAYTGYAAYCCNGAYTGYGAYATH--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHGAYGCNAAYGGNCCNMGNCCNGARCCNGTNTAYYTNMGNMGNGAR AARCARCARCCNCCNAGYYTNGTNGCNTCNAARCAYCCNCAYGGNGCNAGYCCNACNAAY ATGAGYCAYCCNCAYACNGGNCARCCNMGNCCNYTNTAYTAYGGNAAYGAYAAYAAYAGY GTNAAYMGNCARTCNMGNACNCARAGYACNMGNCCNGAYCCNATHCARGGNCARCCNTAY GCNGGNGCNCCNGCNCARMGNGTNGGNAGYGCNCCNYTNMGNAARATHGGN------AAY CARGGNACNATHMGNAGYAAYGCNGCNATHGGNAAYMGNTCNCAYTCNMGNTTYGAYACN GGNATGGARCARGTNCARTCN--------------------------------------- CARCAYCAYCCNAAYTTYYTNCCN------------------CCNATGCCNMGNCCNCCN CARGCNTCN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AAYYTNGCNYTNGGNYTNAAYATGGGNGCN MGNCCNTAYAAYGCNGCNCCNGGNGCNGARGCNGCNAARTTYMGNAAYCCNGGNYTNGTN TCNCCNGGNAAYGGNYTNTTYGGNAAYGCNTTYTTYCARAAYMGNACNATGGCNCCNMGN AGYGCNAGYATGTCNAARGARGTNACNMGNAGYMGNYTNYTNGARGAYTTYMGNAAYAAY MGNATHCCNAGYYTNTCNYTNAARGAYYTNATHAAYCAYGTNGTNGARTTYTCNCARGAY CARCAYGGNTCNMGNTTYATHCARCARAARYTNGARMGNGCNACNCARCARGARAARGGN ATGGTNTTYGCNGARATHYTNTCNGCNGCNTAYTCNYTNATGACNGAYGTNTTYGGNAAY TAYGTNATHCARAARTTYTTYGARTTYGGNTCNCARGAYCARAARCARACNYTNGCNCAR MGNGTNMGNGGNCAYGTNYTNCCNYTNGCNYTNCARATGTAYGGNTGYMGNGTNATHCAR AARGCNYTNGARTCNATHCCNTCNGAYATGCARGTNGARATHGTNAARGARYTNGAYGGN CAYGTNYTNAARTGYGTNAARGAYCARAAYGGNAAYCAYGTNGTNCARAARTGYATHGAR TGYGTNGARCCNGARTAYYTNCARTTYATHATHGAYGCNTTYAARGGNCARGTNTAYAAY YTNTCNACNCAYCCNTAYGGNTGYMGNGTNATHCARMGNATHYTNGARCAYTGYAAYCCN GARCARACNCARCCNGTNYTNGAYGARYTNCAYGAYAAYACNGARMGNYTNGTNATGGAY CARTAYGGNAAYTAYGTNATHCARCAYGTNYTNGARCAYGGNMGNATGGARATGAGYACN TCNGTNGGNACNATGMGNGCNGGNTCNAAYAARYTNYTNGGNCCNAARGARAARCARGCN AARGGNGARAARAAYACNGCNTCNCARCARACNGTNGTNGTNAARTCNGARAAYCAYTCN AGYAARATGCARCCNACNCARGARCARYTNMGNTTYGCNCARATGATGAGYACNAAYCAR ACNGAYGCNGAYCCNAAYACNGTNAARCARYTNATGGAYATGACNGGNAARAGYGARGAY GTNGTNGTNATHGCNYTNCAYGAYGCNGGNAAYGAYGCNGARMGNGCNGTNATGATGYTN YTNGARGGNGGNGAYGARCARGGNGARTGGYTNGARCARGGNGGNAARAARAARAARAAR ---AGYACNCARAARGARAAYGCNAAY------GGNGARGAYCARTCNGAYACNMGNCCN AAR------------GARMGNAAYACNGAYAARAGYGGNGAYAAYCARGAYATGCCNCCN MGNMGNGGNMGNMGNAAYGGNGGNCCNCCNCCNMGNYTNGCNMGNGGNMGNGGNMGNGAY AARGGNAAYTTYGGNGAYMGNGAYAARGARMGNAAY---AAYGCNGCNGARGAYTGGGAY ACNGARAARGARGAYAARGGNTCNGTNCCNMGNAAYGARMGNGAYMGNAGYGGNGGNGAY MGNGGNMGNTCNMGNGGNMGNGGNGGNTTYGGNGGNMGNAARACNGCNATH--------- AGYGGNGGNMGNGGNMGNTTYAAYAAYAGYAAYGAYMGNGARAAYMGNGGNTTYACNMGN CCNMGNMGNTTYGARAARATGAAYAAYAAYCARCCNTCNGAYGGN------CCNGARATH GAYACNTGGACNAAYGARACNGCNCARAGYAAY---GTNTCNAARGAYACNGAYTGGAAY AGYTGGAAYGARTCNTGGGTNAAYGARGARGAYCARTGGACNGGNACNYTNGAYGARACN ACNGTNTTYACNCCNTCNCAYGTNAARATHCCNGARCCNGAYCCNGTNAGYAAYGAYCCN CCNAGYTCNYTNGGNCARMGNYTNGAYGTNGGNAGYYTNTTYGARAAYGCNAARTTYACN AARGCNCCNGAYTAYAGYAARCCNAGYGGNGAYTCNTAYATHACNCARTTYAAYCARGCN GCNACNGARTCNATHAARAAYACNATHGGNATHGGNAGYACNTCNMGNTCNCARATHGGN ATHTCNGCN---------------CARAAYTCNTCNAGYTCNYTNGGNYTNTCNAAYYTN GGNCARAGYTCNGGNCARGTNCARGGNAGYTCNGTNYTNTCNCCNYTN---CARCARTCN GGNACNCARAAYGCN---ATGCCNCAYGCNATHGCNCARYTNTCNCARATHCARCAR--- ---------------------------------------CCNACNTCNCARGGNAGYATG TCNCCNATGGCN------------------ATHGGNTCNCARAGYCARGCNAAYAGYAAY CARGCN---CCNCARCARTCNMGNATHCCNGCNGTNGTN------------------CAR CARCARCARAAYYTNCCNCARGCNAGYATG---AAYAAYATGCARCARMGNCCNAARCCN CARMGNTCNAARYTNCCNCCNCCNTCNAARATHCCNTCNACNGCNGTNGARATGCCNGGN CAYATHCCNMGNAAYCCNCARYTNGAYGTNCARTTYGGNYTNGAYTTYGGNTCNGARTCN TCNGTNCARTTYGGNTTYGGNGGNAGYGGNGAYAGYACNTCNGTNACNAGYTCNTAY--- TCNGCNTCNAAYGGN---ACNACNGTNATHTCNAAYCAYYTNAAYCARGGNCAYGTNAGY CARTCNGCNGGNGAYGGNAGYTCNGTNTCNACNATHATGCCNTCNCCNTCNGCNGGNTCN TCNAARGTNCCNTCNGGNATHGARCCNCARGTNTCNAAYMGN---CARGGNGTNTTYCAY AAYTCNGTNTAYTCNTCNCCNCARTCNAARAAYGARAGYCARGCNYTNGARMGNGAYCAR AAYAARGTNAAYGARTCNATHCCNTTYYTNTCNGCNCARYTNGAYMGNAARTCNAGYCCN YTNACNTCN---CARCAYCCNGTNCCNGCNAAYCARAAYYTNAGYTCNGGNTCNATHGCN TCNAAYAARGAYACNACN------AAYGCNGTNGCNAAYAGYTAYTCNTCNGCNAAYGGN TAY---ACNGCNTCNTAYCARACNCAYCCNAARGGNTCN---------ATHTCNCAYACN ACNAAYTCNCARGCNCCNCARACNTCNTCNTTYCCNGGNCARTAYCCNGTN------CAR TCNTAYCCN---TCNGGNCARACNCARTTYCCNGCNCCNCCNAAYACNACNCCNTTYCCN TCNGCNTCNACNCCNTAYAAYTCN---------ATHTCN------TCNCARAAYCARTTY TCNTCNGGNCARAAYCARTTYTCNGTNGGNGCNYTNGCN---------------CAYCAR AGYCARTAYGCNCCNAGYGCNCARAAYAGYTAYGGNAAY---GGNCCNTCNCARTAYTCN GGNTAYCARAAYACNAGYTCNTTYCCNTCNCAYCCNCARTCNCARCCNAAYTAYCCNTCN AAYCARATHGTNGGNACNGGNACNGTNYTNTAYCCNACNTCNACNCARTCNAGYGTNCCN YTNTAYACNTCNCARTCNAAYTCNTAYCARTCNCCNTCNTCNGGNTCNTTYCAYTCNTCN MGNGAYGGNCCNAGYAAYATGACNGTNACNACNCARTCNTCNAGYGGNATGTCNTTYTCN AGYCARACNCARAGYCCNAAYYTNAARCCNGCNGTNACNCARAGYAGYTCNAAYTAYAAY TCNCARGGNTAYAAYACNACNCCNACNCCNYTNCARCCNTCNTCNYTNGCNAAYAARYTN GGNGARGGNYTNTCNAARATHTCNATHAARGAYTCNACNACNGTNYTNGAYAAYCAYCAR TCN---CARTAYGARCAYTCNGCNGCNCCNACNATHGTN------------AGYYTNCCN TCNGCNTCNAGYTCNGCNTCNYTNTCNACNGGNACNAAYACNATHTCNTCNTCNTCNACN GTNACNAGYGTNTCNTCNGCNTCNMGNGTNGCNTCNATGCCNTCNACNTCNGGNAARGCN CCNCCNAAYYTNCCNCCNGGNGTNCCNYTNATGGGNCARTAYATHATGGGNCARAGYACN YTNCCNCCNTTYTAYAGYGTNCARCCNCCNATGTAYGGNTAYGARGAYGTNCARYTNYTN CARCARMGNATGCCNATGCARTCNGGNAGYTTYTAYGAYATGAGYGCNTTYCCN---GCN CCNGCNGGNTCN---------ACNGGNMGNGARCARCARCCNCCNATHCCNAGYGTNCCN TTYTCNGGNACNTCNGAYACNAARYTNACNMGNGTNGARGCNCARAGYCCNAAYGCNTCN AGYCARCCNCARAGYGCNCAYTCNGCNGCNCARCARCCNYTNTTYAAYTTYCAYTAYGGN TAYTAYTAYCCNTCNATGTAYCCNGGNGCNGCNGGNYTNCARTAYCCNACNACNGTNTAY CCNATHCCNCCNGTNACNAAYGCNGCNGCNCAYCCNGGNACNACNTCNACNACNCARTTY CARAARTCNTAYCCNTCNCAYGTNTAYACNACNAARGGN--------------------- ------------------------------------------------------------ ---------------TCNGGNACNAAYGARATHACNCCNAAYGCNTAYAGYAARTCNCAY GGNCAR---GGNTTYGAYAARCARGGNTAYCAYGGNGGNACNCCNCCNCCNTTYAAYYTN CCNYTNGCNACNGCNGCNCARACNGGNCCNATGGGNGCNCCNACNACNCCNTAYGGNGCN CCNTTYYTNCCNGTNATGGCNGCNCAYCARCCNCAYTCNCARATGATGCAYCAYCCNATH CARCARGAYTCNAAYAGYAGYAGYTCNMGNGGNYTNAAYCCNGGNGGNAGYCARGGNAAR TCNGGNAAYGCNAARTCNTTYGGNGGN---CCNCCNTAYTGGAAYAAYCCNACNGCNATH TCNTAYYTNCCNGTNCCNCARYTNTGGGGNTTYATHTTYTTYYTNATGYTNTTYTCNYTN GGNYTNGAYACNCARTTYACNAGYGTNGARACNYTNYTNACNACNYTNGTNGAYGTNTAY ACNTGGATGGTNAAYTGGMGNAARACNACNAGYGCNGTNACNATGYTN---YTNYTNACN ATHTCNTCNYTNATHTTYGCNACNAAYGGNGGNGTNTAYYTNTTYACNYTNGTNGAYTGG TAYATHGCNGCNTTYTCNATGATGTCNCARGCNGCNYTNGARTGYATHGTNGTNTCNTGG ATHTAYGGNGCNGAYMGNTTYTGYMGNGAYATHGARYTNATGYTNGGNMGNAARCCNTAY TAYGCNTTYGTNATHTTYTGGAARTTYATHTGYCCNGCNGTNYTNYTNYTNGTNYTNTGY GTNACNYTNGCNACNTTYAARGCNGCNAARTAYGGNACNTAYGCNTTYACNGAYACNGCN CARGCNTTYGCNTGGGTNYTNTCNGTNGTNCCNTTYACNGCNATHGTNGTNATHGCNGTN ATGGARYTNYTNAARCAYAARGGNTCNYTNAARATGMGNYTNAARAARGCNTGYMGNCCN GAYCCNGARTGGGGNCCNGCNYTNGCNGAYTAYMGNAARAARTAYATGGGNGTNYTNGAY ATGYTNAAYCCNGCNYTNYTNYTNAARYTNMGNYTNATHGTNTAYGGNATGMGNGAYAAR TTYTCN---------------GGNGTNGCN------------------------GAYACN TGYCCNYTNTAYTAYAGYCCNMGN------------GAYACNCCNCCNAAYTCNAAYTGY AAYTAYCCNATGGCNATHTCNATHATGTTYCARYTNYTNTAYYTNYTNTTYMGNGTNTCN ACNYTNGTNYTNGTNYTNYTNGGNAARTTYACNGCNGAYATGGTNYTNTTYTCNGAYATH GCNGARYTNGCNTAYGTNGTNGTNGAYYTNGTNGCNTTYTTYYTNATHTTYATHGCNGCN TGYATHYTNTCNGCNGGNACNAAYTCNYTNTGYGAYTCNYTNCAYTGYGGNCAYTCNGCN ACN---------YTNTCNGCNTCNAARGCNGCNCARGCNGGNGCNTGGATHAGYACNTTY YTNTGGYTNTTYGTNGGNATHTGYGGNTTYATHACNYTNTGGMGNGCNGGNAARATHCCN TTYYTNCCNGGNGGNGGNTCNGCNAARACNGARACNTCN---GCNACNTCNGAYTCNAAY CARCCNCCNATHGARACNCCNCCNTAYAGYCCNGAYGARCCNCCNMGNTAYGTNATHTAY TAYAGYCCNAGYGAYGCNATGYTNACNTCNYTNGARGARATHMGNGARTAYYTNYTNAGY CAYGAYACNTGYAARTGYGGNYTNGARTGYCCNTTYCARYTNGARGAYGCNTTYGTNTTY GAYCCNGCNATHAAYAAYYTNCCNTGGAGY------------------------------ ------------------------------------------------------------ ---------------------------------------------AAYATGGAYTCNGCN YTNAARAGYMGNATHMGNMGNMGNYTNTAYCAR--------------------------- AGYGARGTNGCNTGYYTNAAYACNCCNTCNYTNCCNYTNACNGARGCNTCNGTNGARTAY TTYCARGAYAGYTTYCCNGGNGARGARGGNYTNGGNMGNYTNGAYATGCCNACNGCNACN GCNGTNAGYAARTCNAARTCNGTNTCNCCNTGYTCNATGGTNATHTCNATGYTNTAYGCN AARMGNYTNMGNCARMGNAAYGCNCAYTAYYTNAARGCNATGTCNTCNACNGAYGTNTTY TTYATHTCNATGATGATGGCNAGYAARTAYYTNTAYGAYGARGGNGTNGAYGARGARGTN TAYAAYGAYGARTGGGCNGARACNACNGGNCARGARGTNGARGAYGTNAAYCAYATGGAR ATGGAYTTYYTNAARGARATGGAYTGGCARYTNTTYGTNAARCAYGARGARTTYGARACN GCNYTNACNGCNYTNGARMGNMGNYTNGCNYTNAARGARGGNGTNAAYMGNGGNTGGTTY ACNTAYTCNGARYTNTCNGTNYTNYTNGAYTGGGAYCCNGTNTAYCARYTNTGGAAYCAR GTNGGNGTNGAYTGYACNAARATGGTNTCNYTNYTNTCNGCNGTNTAYGTNACNAGYYTN GTNAGYATGATGGGNTCNGCNGCNATHGCNGTNCARYTNTCNGGNCCNYTNACNACNGCN ACNYTNGCNGTNGTN---------------------------------------AAYGAR MGNAARTGYTGYCCNMGNGCNTGGMGNTAYCARTGYMGNAGYTAYAGYAARCCNATGCCN TGYTTYMGNAAYTAYTAYCAYGGNMGNMGNGARACNTGYTGYCCNATHTGGCCN---MGN CCNATHTAYGTNGCNMGNTGYCARTGYAGYGARTGYGCNGTNCARACNTCNACNTGYATH CAYAARGGNMGNTGYGCNCAYMGNTAYGCNAARMGNTCNTTYGTNGCNATHTGY---TAY AGYMGN---TAYCCNMGNATHACNTAYATG---AARAARTAYGTNCCNACNAGYTGYTAY TGY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ATGGTNTGYGTN CCNTGYTTYYTNATHCCNGTNATHYTNTGGGTNTTYCAYAARTTYATHCARCCNTGGYTN TCNAARTTYTGGAGYGGNTCNGARAAYTAYGTNACNAGYAAYYTNACNTGYCCNATGCCN CARAARAARAARAARACNGARGARGGNGCNGARGGNACNAGYAARCCNACNGTNGARGGN GARGARAGYGGNGAYATGTCNAAYGCNGGNTTYTTYMGNGGNACNACNGCNCARCARGAY ACNMGNTTYTCNGAYAARAARAARAARYTNATGAARACNATGMGNTTYGGNGAYGTNYTN GARAARAARGTNGAYATGACNAARGTNAAYGTNGAYAGYYTNAARCCNTGGATHGCNCAR MGNGTNACNGARYTNYTNGGNATGGARGAYGAYGTNGTNGTNGARTTYGTNTAYAAYCAR YTNGARGARMGNCAYCCNGAYGGNAARGARATGCARATHAAYYTNACNGGNTTYYTNAAY GGNAARAAYGCNMGNYTNTTYGTNGCNGARYTNTGGGARCAYYTNTGYAGYGCNCARGAR AAYATHACNGGNATHCCNAAYCARTTYYTNGARCARAARAARAAYGARATHAARCARMGN CARGARGARCARGARMGNYTNCARGARCARGTNAARAARAARGARGARCARATHAARGAR CARYTNTCNMGNGARMGNMGNGARYTNGARAARAAR------------------GAYATG AAYAAYYTNTCNCCNGAYMGNCCNAAYMGNCCNGARGARAGYAAYGGNGTNCARCCNATG ATGTCNGCNGGNGGNGAYGGNGTNGARCCNAARCCNGAYGGNGCNGCNCCNAARGARGAR CCNGARGCNTCNGGNGARGCNAARCCNGAYGGNGARGTNAARAARGARTCNAARGARAGY AARGAY---------------------AARCCNMGNGARAARACNCCNGARAARMGN--- ------------MGNGAY------------------AAYMGNGAYMGNGAYMGNMGNMGN CAYTCNMGNACNCCNGAYAAR---CAYMGNCCNMGNTCNCCNGAYMGNCAYMGNMGNGAY MGNGAYMGNGAYMGNCCNGCNTAYGGNTCNMGN---------------MGNMGNTCNMGN TCNCCNMGNMGNMGNTCNCCNTCNCCNMGNMGNMGNTCNCCNCCNCCNMGNMGNMGNTCN CCNCCNCCNMGNTCNGTNTCNCCN---------MGNMGNAARMGNTCNCCNAARAAR--- ---GTNGARAGYAARGCNGCNGCNAARMGNTCNAGYAGYGARAGYAGYTCNAGYGGNTCN GAYGAYAAY---------TCNGGNAARGARGAY---TCNTCNCCNGAYAARACNGGNATH CARCARMGNMGNAAYTAYMGNAARCAYGAYGARGARAGYGGNAARGAYTCNGAYTCNGAY TCNTCNCARGGNGGNGAYAARCARMGNMGNAARCCNCCNCCNCAYMGNGGNAAYMGN--- ---MGN------------AAYGTNMGNMGNACNCCNTCNCCNTTYCARGGNMGN------ ---MGNMGNMGNCCNAGYCCNMGNMGNCARAGYCCNCCN--------------------- ------MGNMGNMGNTCNCCNMGNMGNMGNMGNMGNAGYCCNTCNCCNMGNMGNMGNTCN CCNCCNMGNTTYTCNCCNCARMGNMGNMGN------AGYCCNCCNMGNMGNMGNCCNTCN ATHTCNCCNMGNMGNMGNMGNCCNTCNGGNTCNCCNCCNMGNGGNCCNTCNCCNCCNCCN CAYMGNGGN---MGNMGNCCNCCNTCNMGNTCNCCNTCNGGNTCNCCNGTNAARMGNMGN MGNCCNTCNCCNCCNCCNAARGCNCARCCNGCNMGNYTNYTNAARAARAARGARMGNTCN CCNTCNGARTCNGAYGAYAGYTCNAGYTCNGGNGARTCNTCNGCNGCNTCNCCNCCNCCN CCNGCNAARMGNCCN---TCNAARGGNAARGARCCNTCNAGYTCNAARMGNGCNGCNGTN CCNCCNCCN---TCNTCNTCNAARCCNCCNCCNCARCARCARCCNGCNAGYGGNAGYTCN TCNTCNTCNTCNGGNTCNGARGAYAGYGAYGARGARGARTCNGARTCNGAYAARCARGCN CCNCCNAARAARGGNMGNGARACNTCNCCNCCN---------------CCNCCNTCN--- ------------MGNYTNGTNAARACNTCNCCNCARCCNGAYGCNAARMGNAARCCNCCN ---------------------CARGGNTCNMGNTCNCCNTCNMGNTCNMGNMGNGARCAR AARCCNAGYCCNTCNMGNTCNCCNCCNCCNMGNAARTCNMGNGAYGGNCCNCCN------ ------------CCNMGNMGNCARMGNAARGAYACNGAYTCNTCN---GAYCARGAYGCN GGNMGN------MGNGAYMGNMGNGCNMGNGAYGARTCNAGYCCNGCNMGN------AAR MGNCCNTCNTCNCCNAGYMGNMGNGARMGNGAYGGNGGNCAYMGNGAYCARCCN------ ------MGNCCNTCNTCNCCNTCNTCNMGNGARAARGCNAGYMGNAGYCARTCNGAYAAR CCNGTNGCNAARAARMGNCCNGCNGCNMGNAARGAYTCNTCNTCNGAYAGYAGYAGYGGN AGYAGYTCNGGNGARGARGARGARAARGARTCNCCNAARGARAARGCNTCNCCNCCNMGN GTNGCNMGNCCNTCNTCNGAYAARMGNGCNGCNTCN------------CCNGCNGGNAAR MGNAARMGNTCNMGNTCNCAYAGYCCNCCNCCNCCNTCN--------------------- ---------------------------------------------------------AAR GCNYTNAARCARMGNGAYMGN------------GAYGGNAGYAGYMGNGAYGAYMGNGAY AGYMGNMGNMGNMGNTCNCCNAGYCCNTCNACNGCNMGNAARGAYACNAARGCN------ ---GCNACNAGYMGNGAYGAYGCNTCNCCNCCNCCNMGNACNAAYGGNAARGTNGGNGTN GCNGCNTCNTCNTCNAARACNAARGAYAARCCNGCNGAYTCNGGNAGYAAYAGYGARTCN GAR---GGNTCNAAYGAY---GGNTCNAARAARAARAARAARAARAARGARAARAARCAY AARAARCAYAARAARCAYAARAARCAYAARCAYAARAARGARGTNCCN---------GAR AARGGNGARGAYYTNGARCARMGNYTNMGNGARAARGCNYTNYTNTCNYTN------CAY MGNAAR------------------------------------------------------ ---------AGYGCNYTNGAYAAYAAYCAYTCNCAYTTYATHYTNTTYGGNGTNGARATH AAYTTYMGNGGNCARYTNGAR--------------------------------------- ------------------------------------------------------------ ---------AARCCNAARGAYYTNGTNAAYYTNGGNTTYTTYTAYGCNGGNTAYTCNGAY TGYGCNMGNTGYTTYTAYTGYGGNYTNGGNYTNAARTAYTGGMGNGCNAAYGAYAAYGCN TCNTAYCARCAYGCNMGNTTYMGNCCNCARTGYYTNTAYAAYMGNTTYGTNAARGGNCAR CARTAYGTNGAYCARGTNCARMGN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GAYGARYTNAAYATHYTNYTNGTNGGNGCNGGNGAYATHMGNCAYATHYTNACN ACNYTNGCNMGNMGNTAYMGNCAYAARAARMGNAARYTNAAYTTYTTYGTNGTNGARTCN TCNYTNGARYTNTAYTCNMGNGAYATGYTNYTNYTNATGGTNATHYTNGARYTNCARCAR AAYATGGGNYTNCARGARAARACNCARGTNTTYYTNGARATHCAYGGNAAYACNYTNATH MGNGARCARACNAGYTCNTAYATHGARAARATGTCNCARCARYTNATHMGNATGATHACN GAYTTYGAYTAYYTNGARAARAARTTYCCNTTYYTNGAYYTNAGYCARYTNAARTAYAAR GARMGNGAYTTYATGGARGGNATHTTYAARTTYTGGMGNAAYAARCAR------AARACN CCNTTYGAYATHAGYAARTGYTGGGAYYTNMGNAARMGNCARCARYTNGGNGTNMGNTAY GAYAGYMGNACNAAYGTNTTYGAYTGGGAYTAYAAYATGGARATGGTNGARMGNGGNGGN TCNATHATHCAYAAYAARCARTAYAARTGYTGGMGNGARGAYGGNATHGCNTAYACNATH MGNGARGGNACNTAYGAYGTNCCNAAYMGNACNYTNTCNTCNGCNACNGTNTTYAARCAY GARGGNGARMGNTAYCCNMGNMGNGGNTAYTGGGGNGAYATGATGGTNTCNCCNTAYATH ACNTTYGGNGTNGARACNGARGARAARTCNTTYTAYAARMGNCARAAYAAYCARCAYACN AARACNGCNGARGAYGTNGCNGARTAYAAYATGACNTCNYTNYTNCAYGARYTNATGACN AAYGARAARTAYGARYTNCCNAARGTNGARACNAARAARGARGCNACNACNGARGARAAY AARCAYCARACNGCNACNATGGARGARATHTTYGARGARAGY---------GTNGCNATH AARGAYAAYGGNGTNACNGARGAYGCNTCNGCNGTNGGNGARTCNCARGARAGYAARYTN CCNGTNGAYAGYGARGAYTAYGARTGGTTYCCNYTNGARGAYGTNAARGTNACNTTYYTN CCNYTNGCNTGYGTNGCNGARATGTCNAARAARAGYAARTAYCARCARYTNTTYAAYGCN GTNTTYTTYTCNAAYAGYATGGTNCAYTTYTTYAARCCNGARATGTCNGGNATHTTYGCN GAYAARTGYGCNATHGTNYTNGARACNGCNYTNTTYATGYTNAAYYTNAARAARCARGAR GTNCARGARTTYTAYAARMGNGTNTCNGGNATGGCNGCNAGYGCNGGNTGYMGNCCNYTN GARGARGTNGAYGAYYTNCARGAYTCNTAYGCNACNTTYTGYTTYGARMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNATHAAY MGNCCNMGNGGNGTNTCNYTNGARAARGCNTCNTTYTAYCARGARGGNAARGAYTTYACN TGYYTNACNAGYGGNGARGTNATHTCNTTYGAYTTYGTNAAYGAYGAYTAYTGYGAYTGY NNNGAYGGNTCNGAYGARCCNGGNACNTCNGCNTGYTCNAAYGGNYTNTAYCAYTGYGAR AAYAARGGNTAYAARGGNNNNTAYNNNAARTCNTCNMGNGTNAAYGAYGCNNNNTGYGAY TGYTGYGAYGGNTCNGAYGARTTYNNNGGNNNNNNNTCNTGYCCNAAYACNTGYATGGAN ATHNNNGARNNNGARMGNGCNCARGARGARGTNYTNNNNNNNAAYCARNNNGARGGNTAY AARGTNAARCARGARTAYATGCARCARGGNAARMGNGCNNNNGAYGARAARYTNGCNAAR YTNGCNGARYTNGARAAYGARAARNNNNNNYTNNNNNNNGANAARGANGCNGCNGARGCN NNNAARNNNGARGCNGARGARCCNGARACNATHGCNAARGARGANCAYAARAARGCNTGG NNNGCNGARAARGARGARNNNAARAARNNNAARGAYNNNATHGCNGCNGGNNNNGCNTTY TCNNNNYTNGAYGTNAAYCARGAYGGNAGYGTNGAYNNNCCNGARATNATGNNNMGNNNN GARTTYGAYATHAAYTCNGAYGGNACNGTNAGYGARGARGARGCNAARGARTAYYTNGAR GAYAANGARCARGTNGAYYTNGCNNNNTTYACNGANAARATHTGGCCNAAYATHAARGAR ATHYTNAARGARCCNACNNNNGARGARNNNNNNNNNNNNNNNGARNNNNNNNNNNNNNNN NNNNNNNNNNNNATNNNNNNNNNN---------NNNNNNNNNNNNNNNGAYGAYNNNNNN NNNATHGARGARGAY--------------------------------------------- ---------------NNNGANNNNGANNNNGARNNNNNNGARNNNNNNNNNNNNNNNNNN NNNNNNNNNGARNNNNNNNNNNNNNNNNNNNNNGANGCNGARMGNAARYTNAARGAYAGY GAYMGNGAYATHGAYGARATHAARAARTAYYTNGARACNGAYTTYGGNCCNAAYCARGAR TAYGCNGCNYTNCARGAYCARTGYTTYGARTAYACNGAYMGNGARTAYACNTAYAARYTN TGYCCNTTYGARAARTCNACNCARAARAAYAARAAYGGNGGNATHGARACNTCNYTNGGN ACNTGGGGNAARTGGYTNGGNTCNGAYGAYGAYAARTAYGAYGCNATGAARTAYGARAAY GGNCARGGNTGYTGGAAYGGNCCNAGYMGNTCNACNCAYGTNAAYYTNCAYTGYGGNCCN GTNAAYGARGTNACNAGYTCNTCNGARCCNAGYMGNTGYGARTAYCARTTYGARTTYACN ACNCCNGCNAARTGYGAYCARCCNAARTCNGCNACN---AARGAYMGNCAYGARGARYTN ------------------------------------------------------------ ------------------------------------------------------------ ---------------AAYGTNTCNGGNTCNAGYACNAAYGARTGGAARATHTAYAARATH GAYGAYGCNGAYTGGACNGGNTGYTAYTGYTGYMGNATHTCNMGNGGNGARGARGTNYTN TTYACNCARGAYGCNGTNYTNCARGTN------MGNMGNGGNTTYYTNYTNCCNGAYGTN CCNTAYAARGCNACNGAYAARGTNGCNYTNYTNYTNGGNGTNGGNGAYTAYMGNAGYGAR MGNTCNYTNAGYGCNCCNMGNTTYGAYGTNCARACNYTNGCNACNGTNTTYMGNTCNYTN AAYTTYAARGTNGTNTCNYTNYTNGAYYTNACNAARAARGARATGATHGCNGCNATHCAY GARTTYAARTAYYTNGTNGGNGARGGNGTNTAYTGYGTNTTYTAYTTYTGYGGNCAYGGN TAYGARGCNGGNGGNCARTGYTTYYTNYTNCCNACNGAYGTNCCNYTNGGNTAYGGNACN TCNGAYTGYYTNGCNGCNGARACNATHYTNTTYAAYATHYTNYTNCCNMGNAARCCNAAR ATHTGYTGYATGATHYTNGAYATHTGYMGNAGYTTYGAYGGNATHTCNYTNCCNGGNAAY AAYMGNMGNCCNGAYTTYGAR---------TAYGTNGTNTGYTAYGGNACNGCNCARGGN TTYAAYGCNTAYGARAARMGNATHTCNGGNATHYTNGTNAGYCAYYTNAARAAYATHYTN YTNYTNGAYTAYGGNGTNGARGAYGTNTTYAGYMGNYTNMGNGARGARATHMGNCARGAY CCNAAYYTN---YTNGARMGNGARGARAAYGGNGARAARCARMGNCCNGARATHMGNACN ATHYTNTCNGARCCNAAYMGNTCNTTYCAYGAYGARATHGAYTCNACNGGNTAYACNGAR GTNTTYTCNGCNMGNYTNACNGCNTGGGARAAYTCNCAYMGNCARCCNGARTCNMGNGAR ATHACNGTNCAYTTY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------AARCCNTCNTTYGAY AAYGGNCARYTNTCNTAYYTNGGNCAYGAYATHGARACNATHCCNCCNAARATHATHGAR GAYTAYTGYAAYATHACNCAYMGNYTNGAYYTNAGYTTYAAYMGNYTNGTNTCNYTNAAR GGNYTNCAYCAYTTYAAYTGGYTNAARGARYTNGTNYTNGAYAAYAAYGAYYTNGGNGAY TCNGCNCARTTYCCNCCNYTNMGNGAYYTNCAYACNYTNACNYTNAAYAARAAYAARTTY AARGAYYTNACNGARYTNATHGARCARYTNAARAARGGNTTYCCNAAYYTNACNTAYYTN AGYYTNYTNGGNAAYCARGCNTGYCCNAAYCARYTNTCNTCNTCNGAYAARGAYGAYGAR GAYTAYCARMGNTAYMGNTAYTTYGTNATHTTYAARYTNCARAARYTNAARTTYYTNGAY TCNTCNCCNGTNACNCCNGTNGARYTNGCNGARGCNMGNMGNGTNGGNCCNTTYATGCAR ATHATHMGNCCN---------ACNGTNGTNGAYGAYGARGAYGCNACNGAYTCNCCNCAR TCNCARAARTAYACNCCNYTNCCNACN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------GTNGAY CCNAGYGAYGAYTCNGAYTCNGAYTCNGCNAGYGTNCCNTCNGCNACNCARGARCAYGGN TTYCARCCNAGY---GGNYTNAARCCNGGNAARAARACNAARGGNMGNGTNAARATHAAR ATGGARTTYATHGARAAYAARYTNMGNMGNTAYACNACNTTYAGYAARMGNAARACNGGN ATHATGAARAARGCNTAYGARYTNTCNACNYTNACNGGNACNCARGTNATGYTNYTNGTN GCNAGYGARACNGGNCAYGTNTAYACNTTYGCNACNMGNAARYTNCARCCNATGATHACN AGYGARAGYGGNAARGCNYTNATHCARACNTGYYTNAAYTCNCCNGAYCCNGCNYTNGGN ACNCARTCN------AAYTCNYTNGARCARMGNATGAAYCCNTCNGGNTTYGARGARACN GARYTNTCNTGYGCNGTNGGNGARGARGARCARAARGTNYTNGARACNGGNAAYGGNAAR CCNGTNTTYCCNATGGGNACNCAYGTNGCNACNCCNACNCARAAYATHCAYGAYMGNACN ATHTTYAAYTTYTCNCARCCNCCNGCNGCNATHTCNATGACNCARGCNGAYCARYTNACN GGNCARCARTTYATHACNATHCCNATGCCNTCNAGYACNGTNMGNTCNATGATHGARYTN TTYTGYAARATHYTNGGNGAYCAYGGNATHTCNGAYGTNMGNGCNGARACNYTNMGNCAR GGNAARTTYAAYMGNGAYYTNGGNGCNAARYTNATGTGGAARGTNYTNTAYGAYGTNGTN TGYTTYYTNGAYAARMGNYTNAAYACNYTNCAYGTNAARACNMGNYTNCARAAYTGGGGN TAYYTNTCNAARACNTTYGCNGARYTNCCNACNAGYYTNACNTAYGGNAGYMGNGARATH YTNYTNGCNYTNGGNTGGGTNATHCAYAGYCARCAYYTNGTNGAYGARATHATHCAYMGN AARATHAGYCCNYTNAAYCARGAYYTNYTNTCNTTY---ACNATHGGNGTNGAYATHMGN GARTCNCAYCCNATHCAYCARYTNATHAGYYTNCCNCARAARGARAARYTNCARMGNCAR YTNATGYTNTGYGGNAARYTNAARYTNAARYTNMGNMGNYTNTTYGCNTCNCARCARGAR YTNGCNCAYYTNCAYCARACNATHCAYAGYTGYACNGCNGGNGTNAGYGTNCARCCNGAR ATHAAYCAYYTNACNCCNYTNGARGTNTAYYTNYTNMGNTAYCCNGARAGYYTNTCNACN ATGGTNCAYATHYTNGARGAYGAYAAYGCNMGNYTNAARMGNYTNYTNGAYTGGAARGAR AARGAYCARATHTTYTGGGAYTGGATGAAYAGYGTNYTNACNYTNCAYGCNCARGARGGN GGNAGYGARAARCARGGNCARGARCAYATGGGNGARGARTCNGTNTTYYTNGAYACNCCN YTNCAYATHGGNGARCARATHTCNACNYTNMGNGCNCAYATHMGNGAYTTYATHYTNGGN CAYGARGARGAYATHGARACNYTNGARAARYTNGTNATGAAYAARAARATHTCNCARATH GAYYTNGARYTNATHAAYMGNCARGTNGARAARGARYTNTTYGTNYTNTCNCARAARTTY TCNCARTAYGAYAARGGNTGYTTYGAYGTNCCNGCNMGNTTYGAYAGYGGNATHGARGCN TCNATHGARAARTTYGAYTGYGTNCCNTTYGAYGGNGTNATHAAYAGYATHACNMGNAAR GGNCARCCNCARACNGCNCARAAYGTNAARGCNGCNAARGARGCNGARATHACNCAYYTN GTNCARAARGARATHTCNGCNYTNCARATHAARGTNGARACNYTNGARCARGARYTNAAR CARGCNCARGTNAAYCAYYTNAARAARYTNCARAGYATHGCNGARAAYGAYGTNAAYTCN ATHTGYATHYTNCCNMGNCAYTTYAARCARTTYYTNCCNTCNAARYTNGAYYTNMGNAAR TCNTCNTGGYTNAAYGGNTTYATGATGTTYAGYMGNGTNCAYMGNAARAARTTYATHMGN AARCAYCCNGGNGTNCAYACNGCNCARATHAGYAARYTNATGGGNCARGCNTGGMGNGAR ATGTCNGGNCARCARCARCAYYTNTAYMGNGARCAYGCNMGNYTNTGYTCNCARGARYTN CARCAYGTNYTNGAY--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ATGTGGACNCCNGAYGAYGCNGGNGTNGTNTTY TGYGCNTGGGCNCAYGARCCNTAYMGNYTNGGNYTNAARCAYTGYTGYCARMGNAARGGN GGNYTNTAYTAYYTNGAYATHCARAARGGNTCNGTNGAYYTNYTNAGYGARGARGGNAGY ACNGTNMGNTTYCCNMGNTTYAGYCCNGAYATGAGYMGNYTNGTNTAYTTYGAYAAYCCN GTNGGNGGNGCNCAYYTNCARTGYAAYMGNATGGTNATGATHGAYTGGGCNACNMGNACN MGNAARACNGTNGTNGARATHGTNMGNCAYGCNGARGCNTCNTCNTTYCARGGNATHTTY ATHGGNATHYTNCCNMGNAAYGTNTGGTTYGAYGAYAGYATHCAYYTNGCNYTNTCNGGN CCNTGGMGNAGYGTNACNMGNACNGTNATHATHAAYACNAAYACNGGNAGYGTNGTNCCN YTNTCNAAYGGNTCNAARGTNGARAGYACNGCNYTNYTNGGNGTNCARGGNCARACNYTN YTNYTNAAYACNTCNTCNCCNTCNACNCCNTTYCAYYTNACNYTNGCNMGNYTNCARAAR GTNGGNGAYCCNTCNTCNGCNYTNTGGATHTAYCCNGAYGGNACNCCNGARAARYTNGAY TGGYTNTCNTCNTGGGARGTNATHCARCAYACNCCNACNCCNGAYMGNGTNMGNGCNAGY AAYGARAARYTNGAYTAYGARAGYATHYTNTGYYTNCCNAARGCNGARAARGAYGGNAGY YTNCCNCCNYTNATHGTNTTYTCNCAYGGNGGNCCNCAYGTNTCNTTYGAYGTNTCNTTY AGYGARTGYGCNAAYTTYTTYTGYYTNTGYGGNTAYGCNGTNYTNMGNACNAAYTAYMGN GGNTCNTGGGGNTTYGGNGARGAYAAYYTNGARTCNYTNYTNGGNCARATHGGNGAYATG GAYGTNAARGAYGTNGARAGYGCNATGATGTCNGTNGTNYTNMGNGGNGTNGTNGAYGGN AAYMGNYTNATGGCNTTYGGNGGNTCNCAYGGNGGNTTYYTNTCNACNCAYYTNGTNGGN CARTAYCCNGARACNTTYAARGCNGCNTCNGTNMGNAAYCCNGTNATHAAYYTNACNACN ATGTTYGGNACNACNGAYATHCCNGAYTGGATHTGYGCNGARGGNGGNGTNCCNTTYCCN ATGGAYGCNCARATGGAYGARGCNATGTTYCCNGAYATGTGGMGNMGNTCNCCNATGGCN TAYGTNAAYCARGTNTCNATHGARTAYTAYAARMGNCAYGTNCCNGTNMGNTGYYTNACN TAYCCNTCNAGYAAYCAYAGYYTNGCNGARGTNGARGTNGARGGNGAYTCNYTNATHAAY ACNATHACNTGGTTYATGAGYGARAAYMGNGARCARGGNGARGCNTTYGTNACNYTNGCN ACNAAYGAYACNTAYTCNYTNGGNTGYYTNGTNYTNGGNAAYTCNYTNMGNMGNGTNGGN ACNACNMGNMGNYTNGTNGTNATGATHACNAGYGGNGTNTCNAARTCNATGMGNACNCAR YTNGARGGNCARTTYGAYCARGTNATHGARGTNAAYATGYTNGAYAGYTCNGAYGCNTGY AAYYTNAAYYTNYTNGGNMGNCCNGAYYTNAGYGTNACNTTYACNAARTTYCAYTGYTGG MGNYTNACNCARTTYACNAARTGYGTNTTYATGGAYGCNGAYACNYTNGTNYTNMGNAAY GTNGAYGARYTNTTYGAYMGNGARGARYTNTCNGCNGCNCCNGAYGCNGGNTGGCCNGAY TGYTTYAAYTCNGGNGTNTTYGTNTAYGTNCCNTCNYTNGARACNTAYACNAGYYTNYTN CARTTYGCNGTNTCNCARGGNTCNTTYGAYGGNGGNGAYCARGGNYTNYTNAAYYTNTAY TTYCAYACNTGGGCNACNGCNGAYATHGGNAARCAYYTNCCNTTYACNTAYAAYGTNGTN TCNCARGCNTTYTAYAGYTAYYTNCCNGCNTTYAARCARTTYCARGAYAAYATHAARATH GTNCAYTTYATHGGNGCNGTNAARCCNTGGCAYCARCCNTAYAAYGCNCARTCNGGNGTN GTNACNTCNYTNCCNGGNTCNGGNCAYAAYCARGARTTYYTNCARATHTGGTGGGAYATH TTYATGGAYAARGTNMGNCCNTAYYTNGAYCARCARYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------CCNCCNGGNATGTCNGCNACNYTNCARGGNYTNGTNTCNGCNYTNCAYTTY GGNTTYGGNTGGGGNTGYGGNTCNYTNATHGCNGGNCCNYTNTAYGARGCNATHGGNGGN CARTAYATGTTYYTNACNYTNGCNATHGTNTCNTTYGTNAGYYTNATHGTNGTNGCNGTN YTNGTNAAYTGY------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ GTNACNCCNCCNTAYTCNGGNGGNAGYACNCCNCAYAGYCARTCNMGNGCNACNTCNCCN GCNTGGAGYGARAGYAGYGGNAAYATGAGYACNAGYAGYGTNTCNGGNCCNTCNTTYCCN GGNAARTCNTCNTCNCAYGGNGCNCAYCCNATHCCNMGNCAYAARMGNCCNTCNCAYMGN MGNGCNGARGTNAARMGNMGNGAYMGNATHAARACNTGYYTNGAYGAYATHAARGGNGTN ATHCCNTCNYTNCARGAYAARGGNAARYTNAGYGARTCNGCNGTNYTNACNAARGCNGCN GARTAYATHCAYCARYTNAARGAYGGNTTYTCNGARMGNGGNAAYAARGCNGCNGARYTN MGNMGNGARATHGARTGYYTNAGYGGNGARATHCAYNNNTTYCARGARTCNYTNCCNGCN GGNGGNYTNAARGARGARGCNGTNTCNAAYMGNAGYYTNGAYGARCAYTAYACNGARTGG GTNGCNGARTAYAGYAARMGNTCNCCNAARCAYTAYATHTTYGCNTCNATHACNTCNAGY YTNTTYGAYTCNTTYAARCARGTNGTNGGNGAYGCNGGNACNYTNGAYTCNATGGGNMGN CARYTNAARGARTGGCARACNAARTAYYTNGGNYTNCCNGTNYTNMGNAARCARATHYTN AARGGNATGYTNAAYYTNACNMGNAAYAGYGAYATHGTN---------ATGACNTCNGAY AGYMGNCARAARAGYYTNTAYCARTTYTCNTTYTAYTGGGTNGCNATHGTNYTNTGYTCN YTNCCNYTNYTNGCNACNTTYTTYTGYGTNATHTGGTCNGTNATGTTYAAYTTYGTNGAR TCNACNMGNACNCAYTGYMGNGTNTGGAAYTAYYTNCCNTCNGTNAGYGCNGGNAGYTTY TCNCCNCARAARTAYGTNTGGMGNATHTGY------------------------------ ------------------------------------------------ACNCAYTCNTTY YTNTCNACNTCNTCNYTNTGYATHGTNGCNAGYGTNYTNGTNYTNATHATHGGNTTYYTN GGNACNATHMGNTCNGARYTNACNGGNGGNATHMGNTAYGAYTAYMGNACNAARGTNCAR YTN------------------------------------------------CAYTCNGGN TTYATHAGYGTNCAYGAYATHAGYYTNGAYCAYYTNCCNGARGTNYTNMGNMGNAAYGAY GTNYTNGARTAYATHAARGCNGARTGYAARYTNACNGTNMGNGTNAARGTNAARTTYACN AGYCCNAGYMGNCCNGAYTCNGAYGCNTGYGCNAARCAYMGNGGNACNMGNTTYGCNMGN ACNGCNTCNGGNYTNTCNATHYTNGAYAAYCCN---GAYTTYTTYAARAGYAARCCNTGY ACNGTNCCNAARTGYCAYMGNGCNMGNGGNCCNGAYCAYATGATHTAYGGNGAYYTNAAR ATHTTYACNAAYAARCAYGTNGTNTTYGAYAAYGAYGARYTNGCNAARACNACNGTNGAY TTYTTYTAYGAYAGYGAYAARAARGGNATGGTNCARGARTAYGCNGTNGAYYTNTAYTAY YTNAAYMGNGTNACNGAYAARGCNTTYATHAARGTNACNATHCAYGAYCARGAYATGTTY AARYTNYTNGARMGNGCNGAYMGNTTYMGNGCNATHCCNACNGCNGTNATHGAYGCNTGG GCNCCNAAYGCNATHYTNYTNTCNCAYCCNCAYGGNATGCCNAARAARATHTCNGGNATG YTNGTNTTYYTNGAYMGNMGNGAYACNCCNTTYACNCCNGARAARTTYTTYCAYCAYACN ATHGAYATGGAYTAYTTYGGNTGYCCNGGNYTNATHTAYACNAAYGTNYTNMGNGCNTTY TGGGAYTTYTCNAARATHGTNYTNTTYYTNTTYTTYATHTTYATHATHGTNATGGCNTTY GGNGAYGCNTAYMGNGTNTCNTCNACNAAYCARYTNYTNGCNACNGTNGTNGGNGGNATH GTNCCNTTYTTYGTNMGNAAYTTYTTYGCNTCNAARACNACNGTNTCNGGNTTYGAYACN ACNAGYGTNCARTTYAARACNGARTTYCAYACNGCNATHAAYMGNTTYCARCARGCNTGG AAYGTNTTYGAYATHATHCCNACN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TAYTGY GCNYTNMGNAGYACNYTNTTYCARGTNYTNGTNGGNGGNCAYMGNATHGARCCNAGYGCN TGGGGNATHATHGGNATHATGGAYMGNYTNCAYGAYCAYTTYGAYGAYCCNAGYGTNCAR ATGGCNTCNTGGTCNTTYGCNAAYMGNYTNCCNGAYCAYTGYAARGAYAARYTNGCNTCN ATHTCNAARTGYGCNYTNTCNYTNTAYGCNACNGTNGARGARGTNMGNAGYYTNCCNACN MGNCARGARMGNGARAARMGNACNGTNAGYYTNYTNAAYACNAGYGCNACNTTYGAYYTN GARYTNATGGARGGNYTNAARGTNATGATGGTNYTNCARYTNGTNGTNYTNMGNCARMGN YTNYTNGAYGGNGARGAYGTNCCNGTNTTYGTNCAYYTNYTNTTYGCNMGNGAYACNTCN GARACNGTNGGNGAYTTYGTNAARAAYCAYYTNAAYTGYGTNGGNGAYTCNGCNGGNYTN GAYCARGTNGARATGTGYYTNYTNGGNTAYACNYTNGGNGTNMGNYTNMGN--------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------GCNGTNGTN GAYGCNATHAAYCARCARACNGTNACNATHTGGGARGARGARAARACNGARATHGTNGCN ATHAARACNAGYATHATGGGNGGNCARAAYTAYGTNYTNAGYACNYTNGAYGAYATGGGN ACNGCNMGNGTNTTYGCNTTYACNGGNGARAARGTNTAYYTNYTNAARGTNATGAAYGAR ---CCNCARGARGGNGGNTCNAARGTNYTNGCNACNAARTGYGARTCNTCNAAYGARGGN GAYTAYATHGGNGTNGCNYTNGARAAYCCNACNACNYTNGARAARTGGYTNGARATHTAY MGNAARCCN---GARAAYTGGGCNAARGARYTNGARTCNYTNAARAGYCARGCNTCNAAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------MGNYTNAGYCAYATHATGCARATGTAYGARGAYYTNGTNGGN YTNACNGARGTNAARACNGCNCARGAYAARGTNGTNGARGCNGARAARAAYTTYYTNACN GTNCARGARGAYMGNMGNAAYYTNCARCARGAYYTNACNGTNGCNCARAAYGAYGTNMGN ACNATHGGNGCNGARYTNGARAARATGCAYMGNACNGAYCCNTCNTAYGTNGARYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GCNCCNGCNTAYGCNACNCCNCCNGCNTTYCCN CAYMGNGTNGGNYTNGARTCNAGYTCNACNGGNTCNTCNTTYCCNGCNGAYTTYACNAAR CCNGTNCCNYTNGCNGTNGTNTCNCCNGAYGGNMGN------------------------ ------------------------------------------------------------ ------------------------------------------------GARCARTCNAAR YTNAGYGARGCNGCNGCNCCNATHACNGCNGARGCNGARGCNGGNCCNACNCAR------ YTNACNGAYGCNGARYTNGCNGCNMGNYTNGCNGGNGARGAYYTNGGNTAYGAYCCNAAY GAYGARACNATHGCNYTNATGYTNCARAARGARTTYGAYMGNGARTAYGAYTCNGCNYTN TCNAARMGNGARCARAARTAYAAYGGNAAYAGYAARGTNTCNATHTCNTTYGAYAAYTAY AARMGNMGNCAYCARCAR---CARGAYGGNATGGTNGARGARGAYGAYGAYGAYGAYTTY TAYGARGARGARAARCCNAAYTTYCCNACNCCNAGYAARTGGGARTCNAAYAARGTNTCN ATHGGNAAYMGNGGNTAYAGYGGNCARGGNAARAAYATHGTNACNAARCAYGAYAARGTN ATHAAYGGNMGNAARAAYGCNGARMGNYTNATGGARTTYCCNCCNAAYTTYGTNTGYGGN GAYGGNGARGGNATGGAYATGCARYTNCCNAAYCARGTNTTYAAYAARYTNAARMGNCAY TCNCAYTCNGARAAYAARAARAGYCAYAARGTNCAYGARAARAARGAYCAYTCNACNGCN ATHAARGTNGTNGAYGARAARACNMGNATHYTNATHTTYAARATGATHAAYTCNGARYTN YTNMGNTCNGTNGAYGGNGTNGTNAGYGARGGNAARGARGCNGTNGTNTTYAARGCNGTN GGNGGNYTNAARGARAAYGTNGARGTNCCNGARGAYGTNATHYTNAARGTNTAYAARACN TCNATGAAYGARTTYAARACNMGNYTNCARTAYATHYTNGGNGAYTAYMGNYTNTCNAAR GAYGTNYTNAARAARTAYAAYCCNMGNAARATHATGMGNATGTGGGCNGARAARGARTTY ATGAAYYTNAARAARYTNCAYMGNTGYAAYGTNCCNTGYCCNYTNGCNYTNACNYTNAAR AARCAYGTNYTNGCNATGGCNTGYATHGGNGGNAARAARCCNGCNCCNAARYTNMGNGAY GTNAAYTTYAGYACNGCNGAYYTNGARGAYGCNTAYGAYCARACNGTNMGNYTNATGAAR CARATGTAYGAYAARTGYAAYATGGTNCAYGCNGAYYTNAGYGCNTAYAAYYTNYTNTGG CAYGAYGGNAARGTNTGGGTNATHGAYGTNGGNCARGCNGTNGAYMGNGARAAYGCNAAY TCNACNTCNTTYYTNYTNMGNGAYTGYAARAAYATHTGYGAYTTYTTYMGNCARMGNGGN GTNCAYAAYGTNCCNTCNGCNGARGGNYTNTTYAAYGAYATHACNAARTAYTCNATGCAR GGNGARGGNAARGTNTTYGARGCNCARGTNCARMGNTAYGARAARGARGARTAYTCNTTY GAYTAYTTYTTYGARATGTCNACNGCNGCNMGNYTNCARAARYTNGAYYTNGAYGARAGY AGYGARAGYGAYGAYGAYGAYGAY------GARGARGTNGARGAR--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TTYACN TAYYTNGGNAGYCARTCNGTNGTNTGYACNGGNYTNCARAGYGGNGARATHTTYAARTTY GAYGCNCAYAARTAYCCNATHATHGCNATGGGNTGYATHGAYAAYATHGGNAARTTYGTN ACNGTNGAYGGNMGNGGNTTYATHAAYGTNTGGAARTAYGAYAAYCARCAYATHACNCAR TTYGGNTGGTAYTTYCCNGAYAGYAARTAYMGNYTNGAYTTYAAYAARACNATGTAYTCN CCNAAYAGYAAYGAYAARCCNAARGTNATHTTYACNGAYMGNGGNMGNTCNAARACNACN ACNCARGCNAARATHGCNMGNGARMGNMGNGARGCNCARGCNGTNYTNGAYGGNATHCAR YTNGGNAAYCCNTGGCAYGTNAGYGTNGAYAARACNGGNYTNGARACNTCNATHTAYATH CCNCCNGGNGGNTCNYTNGARTCNGGNGCNATGTTYAAYATHATHGTNMGNCAYATHMGN ACNCAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------GARGGNGAYGTN GGNATHACNGARTTYATG---GGNACNCAYACNTCNTTYGARGCNATHATHAARCARMGN TAYTCNGAYTTYATHGTNAAYGARATHGAYCARGAYGGNAAYATHGTNCAYYTNGARAAY ATGGAYTTYGARGARGARGAYGAYAARGAYGARGAYGARGARAARAARYTNTCNGARGCN GCNGGNGTNYTNAGYGARGARGAYATHGCNGCNATHAARAARATHGTNACNGARCARAAY AARGARGGNTCNCAYGAYATHYTNGCNCCNGARGGNAARGARYTNMGNACNAARATHCAY YTNGCNGTNAARCARAAYTTYTCNCARYTNGARACNACNACNACNGARGAYGAYGARGGN AAYAARATHATHMGNGTNGCNTGGMGNACNGGNAARMGNMGNGAYMGNAAYMGNATHGAR TGGCCNGCNTCNAARAARTCNTGYMGNTAYGTNAARTTYGTNYTNTAYAARGARAAYAAR GAYACNATGGAYGCNATHGGNYTNATHGCNAARAAYYTNMGNGTNAARGARAGYATGTTY CARTAYGCNGGNACNAARGAYAARMGNGCNAARTCNACNCARGARATHACNGCNCAYMGN ATHCAYCCNAARCARYTNGTNAAYYTNAAYAARGTNYTNTGGAAYATGGGNYTNGGNCAY TTYMGNTAYGTNCARCARCCNYTNCARYTNGGNCAYYTNTCNGGNAAYCAYTTYGTNATH GTNYTNMGNAAYATHYTNAARGGNCARGAYGTNGTNGAYACNGCNYTNAAYTCNYTNAAR GCNAARGGNTTYATHAAYTAYTAYGGNATGCARMGNTTYGGNACNACNTCNATHCCNACN CAYACNGTNGGNAGYACNYTNYTNCARGGNGAYTGGTCNAARGCNATHGAYYTNATHYTN TCNCCNMGNAAYGAYATGCCNGCNAARGAYAARTTYCARAARATHTGGGCNGARACNAAR GAYCCNCARGCNACNTTYGAYGCNACNCCNGCNTAYTGYGGNYTNGARMGNAAYGTNYTN GGNGGNYTNATGAARAAYATGAARCCNYTNAAYGCNYTNGAYMGNATHTCNMGNAAYACN MGNYTNYTNTAYATHCAYAGYTAYCARTCNYTNGTNTGGAAYAARATGGTNTCNMGNMGN YTNGCNCARYTNGGNCAYTGYGTNGTNGTNGGNGAYYTNGTNATG--------------- ---------AARMGNCARGARGAYTTYTCNAGYCCNACNGTNGTNACNGARGARAAYATH GGNGAYTAYACNYTNGCNGAYGTNGTNYTNCCNYTNCCNGGNTAYGAYGTNATHTAYCCN ACNAAYGCNGTNGGNGAYTGGTAYMGNCARACNYTNACNTCNGAYGGNYTNGAYATHGAY AAYATGMGNMGNCCNCARAARGAYTAYTCNYTNTCNGGNGCNTAYMGNCAYYTNATGGTN YTNCCNAARGAYGTNACNTGGACNCAYCAYMGNTAYAAYGAYTAYACNCARGCNYTNACN YTNAGYGAYYTNGAYGTNATHCARGGNCAYACNYTN---GCN---GCNGGNGAYACNGGN AARYTNTCNGCNGTNGTNGTNMGNATGTCNYTNCCNTCNTCNTGYTAYGCNACNATGGCN YTNMGNGARGTNATGMGNGTNGAYACNTCNTCNTTYCAYCARGCNACNATHAGYATGAAY CCNAGYMGNTCNYTNGGNTCNGCNGTNGCNTCNGARTCNTGGGAYGAYCAYTGGATHTAY TGGGTNGCNCCNATHGCNGGNGGNGTNYTNGCNGCNATHACNTAYAARTTYATHGTNTCN CCNTAYMGNGGNGTNATHAAYATGGARGARGCNGTNGARAARATGAAYGGNGAYGARGGN ATGGTNGTNATHCCNAARGARTAYTTYAARAAYGAYATHAARAGYTCNGAYACNCAYATG ---------------------------AARATGGCNGAYGARYTNCCNATHTTYCCNAAR GCNTCNTCNATGTAYYTNCAYAGYGGNAAYATGATHAAYTGGAAYMGNYTNAARMGNAAR CCNAAYATGTCNTCNTCNGAYGARYTNTAYGARGTNATHACNGARACNYTNGGNTCNTTY YTNGGNGCNGCNGAYAARACNGARYTNCARTAYATHACNGARATHTAYAARATHAAYACN GARAAYATHGARGTNATHGARGARGARGARMGNGGNGAYGTNAARATHACNGTNAARGTN TTYGTNTGYAAYTCNCARTCNACNAAYGTNATHGARGARGCNGTNAGYMGNGTNYTNAAY GARYTNGGNACNCCNTTYGTNGARACNYTNYTNYTNGCNGTNTGYCCNAGYTGYGGNGAY GARCCNGARTCNGARGARGTNGTNAGYYTNTCNACNATHCARMGNTAYTGGCARGCNATG GARGARYTNGTNACNAARGAYAARGTNYTNTCNYTNGGNGTNTGYGAYYTNGGNAARGAR GGNYTNGARACNYTNTAYAAYTGGGCNCARGTNAARCCNATHGTNAAYCARGTNAAYYTN GARTCNTGYTGYGCNYTNCCNAARGAYYTNACNGARTAYGCNAARGCNATHAAYGTNCAR YTNYTNACNCAYAAYGAYAGYCCNGCNTTYYTNACNAARGARCAYYTNCARGARAARATH MGNAGYGTNTCNACNGARMGNGAYAGYGAYGCNTGGTCNCCNGARTGGGTNGTNMGNTAY TCNGCNATGATHAARTGYMGNGGNATHATHAARACNAARGGNTAYATHTTYCAYGCNACN MGNGAYAAYAARAARMGNATHYTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ATGTTYGGNAAYAARMGNCCNYTNTTYGGNGARGARGGNTGGAAYACNGGN YTNGAYACNTCNGGNACNGAYAAYGGNAGYAGYGCNMGNAARAARAARMGNMGNAGYMGN TGGAAYACNGAYAAYGAYGARAARACNGTNATHCCNGGNATGCCNACNGTNATHCCNAGY GAYATGTCNGARGCNCARCARMGNCARTAYGTNGTNCARYTNCARATHGARGAYATHACN MGNAARYTNMGNACNGGNGARYTNGGNATHCCNTCNGTNCCNGARNNNMGNTCNCCNTCN CCNGARCCNATHTAYAAYAAYGARGGNAARMGNYTNAAYACNMGNGARTAYMGNACNMGN AARAARYTNGARGARGARMGNCAYAARYTNATHCARGARGCNGTNAARYTNAAYACNGAY TTYAARCCNCCNAGYGAYTAYAARCCNCCNATHGTNMGNGTNAAYGAYAARGTNATGATH CCNCARGARGARCAYCCNGAYATHAAYTTYGTNGGNYTNYTNATHGGNCCNMGNGGNAAY ACNYTNAARACNYTNGARAARGAYACNGGNGCNAARATHATHATHMGNGGNAARGGNTCN GTNAARGAYGGNAARATHGGNMGNAARGAYGGNCARCCNYTNCCNGGNGARGAYGARCCN YTNCAYGCNTAYGTNACNGCNAAYAAYCCNGARAAYGTNAARAARGCNGTNGARAARATH AARGAYATHATHAARCARGGNATHGARGTNCCNGARGGNCARAAYGAYYTNMGNMGNCAR CARYTNMGNGARYTNGCNYTNYTNAAYGGNACNYTNMGNGARAAYGAYGGNYTNCARAAR YTNMGNCARATHGCNGARTGYCARACNATHGTNACNAAYACNATHGTNTGYACNGTNTGY GGNGGNACNGGNCAYATHGCNCARGAYTGYAARCARAARMGNCCNGGNGAYACNTTYMGN ATGCARCARATGCARAAYCCNGCNGAYMGNGCNAARATGGAYAGYGARTAYATGTCNYTN ATGGCNGARYTNGGNGARGGNCCNCCNCCNCCNAARTCNGAYGGNCAY------CCNCAR ---------------CARCARCARTCNTAYAAYMGNACNYTNYTNTCNAAYCCNCCNCCN AAYCCNATGGCNATHAAYTCNCCNTGGCARATGCAYGCN---AAYMGNCCNCCNATGGCN GGNCCNGTNCCNCCNCCNCCNAAYTCNGGNCCNGCNCCNYTNYTNCAYMGNCCNCCNATG GGNATGAAYACNTCNGCNCCNCARATHAAYCCNATGGGNMGNYTNCCNATGCCNYTNATG TCNACNCCNGTNCARCCNCCNCCNGGNATGCARGGNCCNCCNGGN---ATGCARCARCCN CCNCCNGGNATGCARCARCARCARCARCARCARCAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MGNATHCAYCCN AARGTNYTNGAYAAYATHMGNTAYATGGTNGCNAGYGGNGARACNMGNYTNTAYGCNATH MGNAARCARYTNMGNAARTTYGTNGTNMGNGAYYTNTAYMGNGGNTCNMGNCARGTNCCN GARMGNCAYGAYYTNACNGTNTTYCCNACNGTNAAYGAYYTNAARAAYCAYATHCAYCAR GCNYTNACNGAYATHCARAAYGGNACNYTNGARAAYYTNGCNCCNCAYCARCARACNAGY YTNCAYGTNACNGAYACNGAYTCNCARGAYAARGAYGAYGAYGARAARGAYYTNAARAGY GARYTNTCNGCNYTNTGG------TCNGCNATGCCNGARACNGTNACNGTN--------- ---------------------------------AAYAGYTTYCCNTGGGGNYTNATHCAY CAYAGYGARYTNGCNACNATGYTNACNAAYGGNYTNGGNAARACNGTNGTNATHGAYAGY MGNTCNTTYYTNGARTAYAAYACNAGYAAYATHCARCARTCNGTNAAYGTNTGYTGYTCN AARYTNGTNAARMGNMGNYTNCARCARGAYAARGTNCAYATHGTNGAYYTNYTNAAYCAR ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------GTNMGNCAYGTNGCNTTYATHAARACNCAYAARGCN GGNAGYTCNACNATGGCNAAYATHYTNCARMGNTTYGGNYTNGCNCAYAAYYTNACNTTY GCNYTNCCNAAYAARCCNYTNCAYGTNAAYGGNTTYAAYTAYATHGTNAARCCNGGNCAR YTNYTNACNCCNCARAARATHYTNCCN---YTNCCNGARGGNCARGARTAYAAYGTNYTN TGGAGYCAYAGYATHTAYAAYMGNACNGCNTTYMGNCARTTYATGCCNCCNCCNACNGTN TAYATHTCNATHYTNMGNGARCCNTTYCARCARTTYGTNTCNTCNTTYGARTAYTAYGGN YTNGCNAARACNYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------GGNCCNTGGTTYTGYAARAARTGYGARTCNCARGARMGN ATHGTNMGNGTNAARTGYGARYTNTGYCCNCARMGNGAYGGNGCNYTNAARMGNACNAAY TCNGGNGGNTGGTGYCAYGTNGTNTGYGCNYTNTAYATHCCNGARGCNTGGTTYGCNAAY GTNCARACNATGGARCCNATHGTNYTNATHTCNGTNCCNCARGARMGNTTYAAYAARACN TGYTAYATHTGYGARGARCARAARMGNGAYACNAARGCNACN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------ATGCCNGGNGGNMGNMGNATHYTNTCNMGNATHCARTCN AAYAGYCCNTAYTCNTCNACNGGNAARAGYTTYAGYGGNAGYGGNAGYCAYGGNCCNGAY GAYMGNGARGGNAAYGTNGTNCCNYTNGCNTCNATGGTNGTNYTNCCNAARCAYAGYCAR YTNCCNGAYATHCCNGGNGAYGGNAAYYTNTAYTTYGARTGYATGYTNTTYGTNTTYGGN ATHATHATGATGTGYYTNCARTAYATHAAYYTNTAYAARACNGTNTGGTGGYTNCCNCAR TCNCAYGCNCARTAYGCNYTNAAYTTYTAYYTNATHGAYTTYAAYYTNGCNGTNYTNATH TGYGTNATHYTNGCNGTNMGNTTYYTNATHTGYTTYGTNCARGARGTNCAYAAYAAYAAR ATGYTNTAYTGGCCNYTNTTYGTNYTNAARACNATHATGACNGGNTTYGCNGGNGTNGTN ATGGTNTAYACNGGNTAYAARGTNGTNATGGARCAYGGNGTNGTNACNAGYYTNTTYYTN TGYTAYCCNGCNGTNATHTAYYTNGTNYTNTTYGGNYTNGCNATHAARCCNYTNTAYCAR MGNTAYCARGCNTGGCCNMGNCCNGCNTAYGGNGGNGAYMGNCCNGCNGGNCCNATGMGN ATHAARATHAARGAYGAYGCNCCNYTNTCNCAYACNTGYACNYTNACNCCNGAYATHGTN MGNGARGARGTNGAYGTNYTNAARMGNGAYTTYAAYAGYMGNYTNAARCARATHYTNTTY AAYTCNYTNACNACNTCNTTYTAYGCNACNGGNGTNCCNGTNTGGTTYTCNCARATGAAY ACNYTNTAYTAYGAYTCNTGGTGGATGTGGCARCAYGTNTCNYTNACNTGGYTNAGYGCN YTNYTNATGYTNACNGTNCAYTTYYTNCCNCCNCAYTAYYTNCAYYTNYTNCAYAARAGY GCNMGNCAYYTNGGNMGNTGGCARMGNATGGARGCNMGNCAYGCNCAYGTNCCNTAYAAY GCNTGGTCNGARYTNCARGTNTGGCCNCARGGNGCNYTNGTNAARCAYGTNMGNGGNYTN TTYAARGCNGARGGNATHAAYGTNACNGCNGARCCNGGNAAYAGYYTNCAYAGYMGNTTY TTYYTNYTN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TCNGAYGAYGCNGAY GAYGARTTYGTNGAYGCNGARGAYAGYGARYTNATGACNAAYMGNCCNTCNTCNMGNACN AARYTNAAYAGYATHYTNGCNGAYCARGAYGCNAARATHGARGARGGNGGNATHGAYAAY YTNATGAARTGYCARMGNCAYYTNTTYGARYTNTCNAARTCNCAYCCNAARGAYGCNGAR GTNTTYTGGMGNATHGCNAARTCNGCNTTYYTNYTNGCNGARGARGARYTN---YTNTCN GGNGAYTCNTCNAGYGAYMGNAAYAARGARYTNATGTTYCARGCNAARAARGCNGCNGAR AARTCNATHAGYYTNAAYCCNAARTCNGGNGAYCCNTAYAARTGGATGGCNATHATHYTN GGNAGYYTNACNCARCAYATGCCNGTNCARGAYCARATHAARAAYGCNTTYGAYATHAAR GARTAYATHGARCARGCNATHTTYCAYYTNCCNGAYGAYGCNYTNATGCAYCAYATHATG GGNMGNTGGTGYTAYTCNGTNTAY------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GGNMGNAGYAARTAYTCNGCNYTNGARGAYTTYGCNATHYTNGAYTAYATHATH GCNTAYAARMGNYTNAARGGNAAYGCNYTNTGGAARGAYATGGARAAYYTNGARYTNACN TGYCAYAGYAGYCARAGYATGMGNTCNMGNTTYCAYAARAAYATHYTNCCNMGNYTNAAY GAYTAYGAYYTNCCNCCNGARGCNAARGARMGNYTNMGNGGNCCNCCNACNATHGAYAAR MGNCCNATGCCNCCNGTNCCNAGYYTNCCNGAYGAYGCNGAYCCNGAYATHYTNGAY--- ------GGNYTNTAYGTNTAYCCNTGGTTYCAYGGNTCNGTNAAYMGNGAYTAYGCNAAY MGNAARYTNGTNYTNYTNCCNGARGAYGGNACNTTYYTNGTNMGNAARAGYACNCAYGGN CCN---------CAYCCNTAYTCNYTNGAYATHYTNTTYGARTCNGCNATHAARMGNYTN CCNATHMGNYTNMGN---GAYGAYGGNAARTAYGCNYTNGGNAARGARAARGARAAYGAR CARTCNTTYGCNGGNGTNGCNGAYYTNATHGCNTAYCAYAARGARTAYCCNATH------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------CAYGCNCCNCARCARAARTCNTGGTTYATHGCNGAYATGAARGTN GCNAAYCARAAYMGNCARACNACNCCNTGGATHGTNGTNATGGGNCAYMGNCCNATGTAY TGYGCNAAYGARGAYCCNGCNYTNGCNTGYAAYACNAARGARGCNAAYATHCCNMGNGAY YTNGARGAYYTNATGTTYCAYTAYGGNGTNGAYYTNATHYTNTCNTCNATGGGNCARGGN TAYCARGCNTCNTAYCCNATGTTYAARGGNGTNAARGTNGCNGAYGAYTAYATHAAYCCN YTNGCNCCNGTNCAYGTNACNYTNGGNTCNGCNAGYAARTGGAGYACNCARCAYAAYTAY ACNGARGAR------GARTGGATGAAYYTNYTNCARGARACNCCNCARCCNYTNACNTTY GGNMGNYTNCAYGTNCAYAAYGCNAGYCARYTNMGNGTNGAYYTNGTNTCNTTYGAYACN TCNGAYGTNYTNGCNTCNATHGARATHGTNCARAAYCAYCAYCAYCARTTYTCNACNGCN GGNYTNCCNGCNAAYATHTCNGARMGNATHGARGCNAARATHAARCARTCNGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------ACNTCNYTNGAYGGNYTNCARYTNCCNGAYTTY YTNTCNGAYGGNCCNYTNYTNGGNGCNAARCAYGCNATGCCNACN---------AAYGAY MGNGGNAAR---------GTNGAYGARGAYYTNYTNAGYCARATHCAYATHYTNCARGAR GARAAYAGYMGNYTNMGNAAYGAYATGTCNMGNACNAARCARAARTGYGAYGAYAARAAY CARAARATHACNCARYTNAARAAYGAYYTNGARMGNCARAARAARAARGARGCNGARGAR ACNGCNGTNATGGARAARGCNGTNYTNCARGTNGARGARAAYYTNGTNAGYACNMGNCAR MGNGCNGTNCARGCNGARAGYCARGTNACNAARYTNACNCARGARGTNAARYTNYTNCAR AAYCARGTNMGNAGYYTNTCNGCNGARAAYGARGCNTAYMGNAGYGGNGAYGGNGGNYTN TCNGAYATHMGNGARMGNACNAARTAYTCNTCNGARCARYTNAARATHGCNGCNGAYGTN GCNGARAARAAYYTNAARGARYTNYTNCARGGNGTNGAYCARATGAARYTNYTNTCNCAR GTNYTNGCNACNTGGGARAARATHACNGARGTNAARCCNGAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARAARCARATGGAYTCNAAYYTNGARCARTCNMGNCCN CAYTCNAGY------------------------CAYAGYTCNMGNACNGGNTCN---AGY GARAARYTNGAYCCNTTYMGNTGYGGNACNCCNTGYGTNAGYCCNAAYGTNGTNTCNACN MGNMGNMGNYTNGAYTAYGGNGARGCNATHMGNAARCAYAAY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------AAR ACNCAYYTNAARCARGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------TAYTAYAAR TGYTCNGARTTYCAYGARGAYTTYMGNTTYAGYYTNAGYTTYATHGARAAYTGYAGYAAY ATHCCNGTNTCNMGNTCNYTNTGYGARAARTCNTGGCARTTYMGNAGYMGNYTNAARMGN AARAAYGGNATHATGMGNATGGGNTGYAGYGARYTNGARGAYGGNATHTCNYTNATGGTN TCNYTNGTNTCNATHMGNGTNYTNGGNGGNAAYCARMGNACNGTNGARAARYTNAARACN YTN------------------------------------------CARGARYTNMGNGCN MGNGAYATHGTNYTNGARYTNMGNYTNCCNGTNYTNACNTTYTCNTCNGGNCCNACNAAY AGYATGMGNGGNGCNGCNTTYYTNACNGGNAARMGNGARGCNGTNGTNGTNGAYGTNGGN GGNACNACNAGYGAYGTNGGNGTNYTNAGYAARGGNTTYCCNMGNGARGCNACNACNTAY GTNAARGTNGCNGGNATHAARACNAAYTTYMGNATGCCNGAYGTNATHAGYATHGGNYTN GGNGGNGGNTCNTAYGTNAARGARMGNMGNGGNGAYGAYGAYAGYYTNCAYGARGTNGAY ATHGGNCCNAARAGYGCNGGNTTYAAYYTNCCNMGNGARGCNYTNGTNTTYGGNGAYGGN GARAGYATHCARGGNMGNACNYTNACNGCNACNGAYGTNGCNGTNTTYTCNGGNYTNTGY AAYYTNGGNTCNAARGAYMGNGTNACNAGYYTNGAYTCNAAYGTNATGAARAARGCNGTN GAYAARATHCAYACNATGYTNGARGARYTNGTNGAYACNATHAARYTNAGYAARGARGAR YTNCCNGTNATHATHGTNGGNGGNGGNAGYGTNATHGTNGAYCCNAARMGNTCNTTYAAR GGNGCNTCNGARYTNATHATHCCNAAYCAYTTYGGNGTNGCNAAYGCNATHGGNGCNGCN YTNAGYAARGTNTCNGCNAGYGTNAAYGGNGTNGGNCAYYTNTCNGAYTTYATHGAYAAY GTNGCNATGGARAARGCNGTNAARGARGCNACNAAYAAYATGGAYGAYAAYTCNGTNCAR GARAARAARYTNGCNATHGARGAYGCNAARAARCCNTTYYTNGTNAARGCNMGNGARGAY GTNATGGAYATGTTYTGYGARMGNGCNAARACNGARGTNATHAARYTNGGNGCNAARGAR GGNAGYGTNGARGTNYTNGARAARYTNGAYTCNGTNYTNCCNTAYGTNCCNAAYAGYGGN YTNCARATHAARGTNAARGTNGCNGGNGAYATGTCNAARYTNYTNGAYAGYAAYAGYAGY AGYATHTCNCAYTGGAARGARCCNGARGARACNCARMGNATGYTNYTNAAYGARAARATH AGYGTNGTNAARCARAAYGTNACNTCNACNGGNTCNAAYGTN---ATHGGNGARGAYGAY GGNGAY---GAYGCNMGNCARCAYCCNAARACNCCNTTYGTNGAYGCNAAYTCNGGNGAY TGGGTNYTNTCNGARTGGGAYATGGARTGYATHGTNYTNGGNGCNGGNGTNTAYGGNTGY GGNGGNGGNGGNAGYYTNCAYATHGCNMGNATHMGNGCNYTNAARGCNYTNMGNGAYGGN AARCCNATHMGNGTNGTNMGNCAYGARMGNYTNYTNCARAAYGCNGAYCCNGAYAARGAY YTNGTNYTNGTNCCNGCNGTNATHGGNTCNCCNTCNGTNGGNAAYGARYTNGGNGCNAGY ACNAARMGNTCNCARGARGCNYTNGAYATHATGMGNGAYATHTAYMGN------GAYTTY AARGAYGGNAGYTTYCARAAYACNGAYGGNGTNTCNGTNGARGARGAYGAYTAYGGNACN MGNTAYGTNTCNAAYTAYAARTCNTCNTCNAARGAYACNGAYAAYAGYTAYAAYATHGTN GGNYTNATGTCNGTNGARTTYGGNGGNATHAAYGCNATHGARCARTTYYTNGTNGCNGCN GAYATGAAYYTNCCNGTNGTNGAYGGNGAYGGNATGAGYMGNGCNTTYCCNGARGTNCAR ATGTAYGTNCCNTAYATHTAYGGNAARCCNCCNTAYCCNGTNACNATHGTNGGNCCNGAY GAYACNTCNGARMGNGGNGCNGTNGTNTTYGCNCCNAAYGCNAARGCNYTNGARAAYAAR YTNMGNGAYATHACNATHCARAAYGGNTGYTAYTCNAAYGTNGCNTTYGCNYTNAGYAAR TCNGARGTNTAYACNAARACNYTNCCNTAYATHATHAGYMGNGCNTGGMGNYTNGGNGAY GCNATHYTNMGNGCNMGNYTNCARAARCARTCNGCNGTNGARGCNGTNGTNYTNCARGAR AAYGGNAARCAYGTNATHTCNGGNAARGTNGTNGAYGTNMGNMGNGARACNACNGGNGGN TTYAAYAARGGNCAYYTNGTNGTNGARGGNACNGAYGARTGGGCNGGNCARACNATGYTN ATHGARTTYCARAAYGARTTYYTNGTNATHTTYCCNGTNAARGARGGNGGNGTNGGNGCN CAYGARGGNTGYGTNCCNGAYYTNATHTCNGTNGTNGAYTCNGAYACNGCNGARCCNATH CCNGCNGARGARATHMGNTAYGGNATGMGNATHGCNGTNGTNYTNTCNGCNTCNTGYGAY CARYTNMGNACNCCNGARGCNYTNAARTGGGTNGGNCCNCARGCNTTYMGNTAYTCNGAR GAYGTNTCNTTYACNCCNTTYGCNGARMGNMGNCCNACNGARCCNATHCCNYTNYTN--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGNTGGTAYAARYTNAARGTNACNGTNTTYYTNTCN TCNYTNGCNGGNTGYTCNYTNATGGCNGGNTTYGGNYTNACNATGGGNATGGCNAARAAR AAYGAYCCNAGYCAYTTYGCNAARGGNYTNATGACNTCNAARGARYTNCCNGARAGYGGN GTNGTNYTNGCNGCNMGNACNYTNGGNAARGCNACNATGTAYAAYTTYATHGGNTTYGGN YTNATHGGNYTNGTNGCNTGGAARGTNYTNGGNATHAAYAGYATGGAYGARYTNAARYTN AARYTNGGNAAYGCNTTYCCNAARATHAARAARACNGARGGNACNGGNMGNAAYGAYTTY GCNAGYATHMGNGAYYTNTTYGAYTAYATHATHGCNGARGAYATHAARYTNAARGARGCN AARAARGCNAAR---GAYGARGARATHGARCAYTAYMGNCARMGNGTNAAYAGYYTNAAR ATHYTNYTNGARGARTTYCARAAYCARYTNTAYYTNTAYAARAAYMGNTGYYTNGGNGTN GARAGYATHGTNTAYGCNYTNAARGARACNAARCARGARAAYGTNAARGTNTCNAARCAY GTNAARGCNYTNGARACNGCNATHTCNATHYTNCARAARMGNYTNACNAARAAYGGNYTN TCNAAYAGYGTNAAYGTNCARGAYGCNGARYTNTTYGTNCCNGGNGCNTCNAARCARACN YTNGAYAAYYTNGCNAARGARACNGCNMGNYTNMGNAGYYTNYTNAARCARGARAAYGGN CAYATHGGNAARAAYTCNCARAAYGARATGGAYGAYATGAARACNGTNYTNGARGARATH GARTCNGARAAYAAYGARYTNAARAGYAARYTNAARAGYATGGARYTNATHAARYTNAAR TCNATHAGYGARTAYGARCARGARYTNAARGCNTAYAARGAYGCNMGNCCNGAYYTNACN TCNGAYGTNTCNGTNGGNTGY---------CARGTNCARGTNTCNAGYMGNAAYGAYGTN CARGARYTNAARGARYTNYTNMGNCARACNGTNGARMGNTGYMGNCAYYTNGAYGARCAR YTNCCNYTNCAYGAYTTYGGNTCNGARCARCCNAARGARACNGAYGAYGAYAAYGGNMGN ATGTCNGCNGTNTCNCARGARGARTAYGAYAARYTNGCNTCNAARCAYCARGARGCNYTN GTNATGAAYCARMGNTGGCARGTNTTYTGYAARGARMGNGARAARCAYATHCARGAYYTN AAYGARMGNGTNAAYGARYTNTCNGAYCCN---CARATGACNGCNATGATHGARGARTCN GCN------MGNCARAARACNGCNGCNCARTTYACNTTYGAYYTNAGYMGNAARGAYTCN GARATHGCNGARTTYMGNAARCARATHCARYTNYTNTCNAARGARYTNACNGAYGTNMGN AARTGGCARGCNCARMGNCAYAAYGARAAYAGYACNGTNGARATHYTNAARCARCARATH CARGTNTGYACNGARGAYTTYAAYACNGARMGNAARGAYMGNGARCARGCNGTNCARAAR TCNMGNGCNYTNCARGAYGARAAYTCNMGNYTNAARGTNGARAARAAYGAYYTNATGAAR AARATHGARCARYTNAARMGNTCNAAYGARCARCARTAYGTNGTNTGYTTYGTNTCNTTY CARGARAAYTCNYTNGAYYTNTTYTTYGAYCARAAYTAYTCNTGYCARTTYTGYAARAAY GCNGCNGAYAARYTNGCNACNTAYGAYCCNAGYGAYGTNACNCARATHAARGARTTYATG GARTCNATHAARYTNGCNTTYATHCAYAAYYTNAAYAARYTNAARMGNTTYYTNAARGAR GCNGARYTNGAYCAYTAYGCNYTNTTYMGNGCNYTNTCNTAYYTNAARAARTGYGGNTGY GGNAGYYTNATHYTNMGNTAYGTNAARYTNGARGCNGGNGCNAAYACNAARTCN------ ------------------------------------------TCNAGYATHAAYTGYTAY CARTGY---------CARTAYGCNAARTGYGTNGAYGARTAYGAYGTNAAYMGNTAYTCN AGY------CAYYTNGGNGAYTGYGGNGAYGGNATGTAYTGYGTNAARTAYAARACNATH GTNTGGATHCAYGAYTCNGGNGARATHACNGGNAARACNMGNGARTCNGCNGTNGTNACN MGNACNTGYCARTCNAARAARGGNCARAARGARGGNTGYATHGGNTGGCARAAYAAYGGN GGNGTNACNYTNAARTGYTGGTGYGGNACNGAYGGNTGYAAYAGYGGNACNTCNYTNMGN CCNATGACN---------ATGGCNTCNMGNGGNGGNYTNCCNATHAARAAYGTNGTNACN GCNATHTTYATHYTNYTNTCNYTNTAYYTNYTNTAYATHTAYAAYGTNTCNCARAAYCAY YTNCAYGAYGCNGARGCNACNGGNGCNMGNTAYMGNMGNGARTCNGARGARMGNGTNAAY ACNATHCARGGNYTNATHTCNGCNAARGAYGARTTYCARGARMGNTGYGARGAYGARAAR MGNGARYTNAAYAAYMGNYTNAARTCNGTNAAYCARAARTAYAGYATGYTNGARAGYCAR AAYAAYGARATHGAYGCNGAYTTYATHAARYTNAARCARGAYATGGAYAAYYTNMGNAAY GARCAYATGCARACNGARMGNYTNCAYGCNCARGARTAYGARACNYTNAARCARAAYAAR GARAARGARAAYACNGARYTNACNGARCARYTNTCNGGNTCNAARCARCARAAYCARGAR CARCARAAYACNATHGCNACNYTNCARGCNCARYTNCARAGY------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GGNGAYATHACNYTNCAYAGYATGGGNGAR ATHGTNACNGAYMGNGCNAGYTTYCAYAGYCCNGARGCNATHTAYCCNGCNGGNTAYTGY ATHACNMGNGTNTAYGCNAGYYTNCAYAAR---CAYGGNAARTGYYTNTAYACNTGYAAR ATHTCNGARGGNGAYGAYGGNCCNYTNTTYGARATHGCNCCNGARGAYAGYTCNGAYATH GTNTTYAARGCNAAYAAYCCNTCNGARTGYCAYAGYAAYTTYGTNMGNGCNATHAAYMGN TCNMGNGGNGCNGARGTNYTNCCNACNGARACNYTNGGNYTNGAYTTYTTYGGNYTNTCN CAYTCNGTNATHCARAAYYTNATHCARTCNATHCCNGGNGCNMGNAARTGYTCNMGNTAY AARTGGGTNAARTTYGARATHAAYAARTCNGARTGYAAYGARAAYTTYGTNATHGGNAAR ACNGAYCCNACNATHAAYTAYGARGCNTTY------------------------------ ------------------------------------------------------------ ------------ATGAAYTTYCAYATHGARCARGCNYTNGCNTCNGGNGGNMGNYTNGGN MGNATHACNCARATHGGNCAYGGNMGNACNGTNACNYTNGARACNCCNATGTGYTCNYTN TTYACNAARGGNGGNAGYGCNCCNCAYYTNAGYYTNAGYATGYTNGCNAARATHAARMGN ATHCCNGARATHGCNACNATGAGYATGAAYTCNTTYGTNGAYAGYCAYGAYAGYATHCAY GARTGYGGNAARGGNYTNTCNGGNTTYACNGCNATGAARGAYAARYTNATHTTYTCNACN YTNCAYGAYGCNAGYTCNCCNGTNCCNTCNGGNAARAAYGAYAARTCNGGNGTNGCNGTN TGGGGNAARGGNGGNAARGTNATGYTNAAYCCNACNTCNTAYGTNGCNATGCARGARTCN TTYMGNCCNGAYTGGGTNGTNGCNYTNGGNGAYGGNGAYACNGAYCARGAYTGYGGNGAR AARMGNGCNGGNAARGCNGTNGAYMGNACNYTNGAYTTYYTNGAYATHATHGTNGCNGCN TGGAARAARAGYGARGTNYTNAARAGYTCNAGYYTNATHGGNGTNATHGTNGGNGGNTTY AGYGARMGNCAYMGNCARMGNAGYGCNGCNGARACNTCNACNMGNCCNGTNCAYGGNTTY YTNYTNGARGGNTTYCAYAARGCNGGNAGYAARGAYGAYATGTTYGARAAYGAYGCNTTY GTNCARATHYTNACNAARACNATHAGYTAYYTNCCNGARTCNAARCCNMGNATHATGGAR TGYCCNTGGTCNCCNGTNCARGTNATHCAYGCNTTYAARYTNGGNATHGAYGTNTTYTCN AGYGCNTAYCCNCAYACNYTNTCNGARAARGGNYTNGCNATGATHCARGAYTAYAGYYTN CCNCCNCCNTCNTCNTCNCCNACNGARGAYYTNGARAAYGARAARGARAAYACNAAYACN CCNGGNCCNGTNATHGAYYTNAAYGAYAARMGNTAYTTYGARGAYTTYGGNCCNYTNATG AGYGGNTGYCARTGYTAYACNTGYTCNACNTTYACNMGNTCNTAYATHCAYCAYYTNYTN AAYACNTCNGARYTNYTNGCNTAYGTNYTNYTNACNATHCAYAAYTTYGARMGNTAYTTY GARTTYTTYCAYACNYTNMGNCARGTNGCNAGYAGYGGNMGNYTNGAYGARYTNGARAAR AARYTNTCNAAYCARGARGCNYTNGTNTTYTAYACNATHGAYGAYATHMGNAARTGGMGN TTYMGNAAYGGNACNATHGTNYTNTGGYTNATHTGYAAYATHTTYTGYATHTGGYTNACN CARGCNGCNGCNTTYGTNTGYGCNTCNTGYGTNGTNATHGCNGTNGCNACNYTNTGYYTN TTYCARATHCAYACNMGNATHYTNGAYAARGTNYTNCCNTCNTCNAARYTNCCNGTNACN AARAGYGARCAYGARAGYACNGAYGGNGCNYTNGAYACNGTNCARAAYTTYMGNTAYAGY YTNATHGARATGCAYGAYTTYGTNATHAARTGYAAYGARTAYYTNACNCARTTYTAYTCN ATHYTNAARTGGGAYTCNGCNYTNCCNTCNTTYATHTAYCAYACNGARATGTGYATHTTY GTNATHTGYYTNGTNATGTGYCCNGCNMGNTGGAAYTGYTTYYTNYTNGTNAAYTGGTTY TTYYTNTGYCAYCCNCAYATHYTNCARAARTGYTAYAGYTAYGGNAARGARGAYGTNACN GAYGGNAARGAYTGYGAYATGTCNGAYGCNGAYTAYGARTTYYTNGGNGAYGARTCNATG ATHGGNYTNGAYCCNTCNCCNACNAARCCNGGNATGGTNGCNTAYCAYTAYYTNCCNACN ACNGGNGTNMGNGCNGAYTTYAARMGNYTNATGAAYGAYTTYATHTCNGCNCARACNGTN MGNTAYGARTGYTTYAGYGARATHTGGMGNAARMGNAARTTYAGYTTYATGTGYGCNGGN MGNCAYTCNGARMGNGARGCNMGNGARTTYGTNGARMGNGCNYTNYTNATHGCNYTNGAY TTYTTYYTNCCNCCNTAYCARTTYCARGTNMGNGTNGGNGGNYTNTAYYTNYTNTAYGGN ATHTTYATGACNCARCCNGTNGTNCCNAARGTNAARGTNMGNYTNACNGCNAGYCARTGG CARGAYACNATGATHTTYCARCARGARGCNTCNCARCARAAYCAYYTNGAYGTNGTNTTY GTNTTYAAYAARATGYTNGTNGAYCAYGCNTTYCARTTYTGYTAYACNCCNTCNGARATG AAYGARMGNACNYTNAAYCCNGARAARGARGAYAAYGARGTNAAYYTNGCNGAYGARATG AARGARGARMGNMGNGARATHAAYMGNYTNTTYAAYTAYGARTCNATGGARCARYTNTCN TAYYTNYTNGAYCAYTAYTGYCARATGAARGTNAAYYTNGCNGGNCCNAARGCNACNAAR CCNGAYMGNTCNYTNGAYGTNGTNCARGGNACNYTNGTNGARGAYYTNGTNGGNATGYTN CARTCNTTYAARGARGTNGTNGGNAAYGTNTAYAARCAYGGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARAARGGNAGYATHAGYTTYGAYGTNATHYTNAARCCN GCNGCNGCNGAYTCNCCNMGNCCNGTNYTNCCNMGNTCNCCNAGYGAYAAYAARCARAAR GAYYTNTCNGARGARAARATHGCNATGAARYTNAARAARGCNGARCARMGNMGNAGYYTN ATHGARCARGAYMGNYTNGAYCARATHGCNMGNGARMGNCARAARGCNATHGARGTNATH ATHAARGCNCARTCNGARAGYCARGARTTYTCNAARAARACNGARGARAARYTNMGNMGN TCNATGGARAGYMGNMGNGARAAYMGNGARACNCARATHMGNGCNYTNCARGARMGNYTN MGNGARCAYTCNGTNAARGTNCAYGAYGTNCARAARACNGGNTTYGARATGGTNAARGAR TTYGARGCNAARGCNGARGARAARYTNTCNCARAARATGGARACNTAYGARGARAAYMGN AARAAYCARYTNTGYTCNATGYTNTCNAARYTNCARGARCAYGCNAAYCAYATHAAYGAR GTNTGYGTNGCNAGYGARAAYMGNGGNCCNAAYACNGAYGARYTNCARGARCARYTNGTN YTNAARATGGARAAYGCNYTNAARAAYMGNGARGARCARYTNMGNTGYATHCARGARMGN YTNGCNGARCAYGARAAYMGNATHAARGARGTNCARAARAARAARGGNATGGTNTCNTCN GGNGAR------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARCCNCCNCCNCCNTAYCAY CCNTCNGARYTNAARCARTGGGTNAARMGNGTNAAYTCNTTYTCNACNCARCAYGAYCCN GGNTCNTGGAGYGCNAGYCARGTNGTNGGNGARCCNCARGTNTAYCCNMGNCAYGGNGAY ATHMGNGGNGCNTGGGCNACNGCNATHTGYGAYGCNAAYCARTTYATHGARGTNGARTTY GARGTNCCNGTNMGNCCNACNGARATHAAYATHTAYGARACNNNNAAYCCNGGNNNNGTN GTNAARATHAARGCNMGNGARTCNTCNTCNCARTGGYTNGTNGTNTGGCARGTNNNNNNN CCNNNNNNNNNNNNNNNNAGYMGNATHTTYTCNCCNCCNYTNNNNNNNNNNGCNATGAAR ATHNNNCARYTNMGNATHGARATHGAYTGYACNGCNGCNMGNACNTGGTGYGARYTNGAY GCNATHGARYTNGTNGGNGTNMGNGAYGGNGCNGTNGCNCCNGTNGAYGAYACNCARTTY ATHGAYGAYATGAARYTNYTNNNNAAYAAYNNNYTNCAYAGYGAYGTNATGTTYNNNNNN GANGGNAANNNNGTNTAYGGNCAYAARNNNATHYTNGCNGCNMGNTCNCCNTAYTTYGCN NNNATGTTYNNNNNNNNNNNNGARAAYCAYGTNNNNYTNNNNYTNCCNGANYTNTCNTTY GAYGAYYTNNNNNNNGTNYTNCAYTTYATHTAYACNNNNMGNYTNCCNGAYAAYTGYNNN NNNAARMGNYTNGCNNNNNNNTGYAARNNNTCNTCNACNTTYNNNATHCCNGARYTNNNN NNNGCNNNNNNNTAYNNNYTNGTNNNNGGNNNNAARNNNGARNNNGCNGTNNNNNNNNNN YTNGCNNNNAARNNNGAYCCNNNNNNNNNNGAYATHNNNNNNYTNTGYAARACNTTYATG GCNACNCAYYTNAARGAYATGTCNAARGARNNNTCNTTYNNNTCNYTNCCNNNNAGYGAY ATHGTNGCNNNNGTNCARGARGCNACNNNNGCNNNNNNNYTNAAYGAYGAYGARCCNGCN YTNTCNGARGARGARGGNGAYMGNYTNATGTTYYTNATHGARAARYTNTGYCAYAARGAY CCNCAYCARYTNTTYYTNMGNYTNGARTCNCARGTNMGNGARATGGTNATHGARATH--- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------TGGGGNTTYACNMGNGCN MGNMGNACNCARGCNGTNCCNMGNCAYTCNYTNTTYGGNACNAAYYTNGAYCAYGTNGAY CARGARGARYTNAARGAYATHGARGGNMGNTAYATHCCNGARGGNTTYATHAARGARTCN CCNAAYMGNTAYCCNYTNCCNCCNCAYATHAARGARMGNATHCCNGGNMGNAAYTCNGTN CARACNTAYCARAARCARTTYGCNGARCARMGNGAYGCNTTYTCNCARGCNGARCAYCAR YTNAARGAYAARTCNGARAARTCNYTNTCNTTYMGNCCNTCNGGNGAYCARCAYGGNTCN AAYAAYAAYTCNGCNCAYTCNCARCAYCCNACNTGGYTNTCNGARAARGAYYTNAARCAY TCNAARGAYATHAAYATHGTNGGNTTYTCNCARCARGGNAGYTAYAAYMGNGAYAARTAY CARAARAARCCNCARGTNCAYAAYTAYAGYYTNATHGGNGAYATHYTNGCNCCNAARATG GAYTTYAAYTCNCCNMGNAARGARGGNCARAARCCNGGNTCNGARGGNAAYACNACNAAR AAY------GCNTGGGGNCCNGGNMGNCAYYTNCCNAAYAARATHACNGAR---CARAAY ACNTCNAARAARAARAAYYTNCCNAARAGYGTNATHGAYYTNCCNCCNAAYATHMGNCAY CARTTYGGNAGYMGNATHTGYGAYTCNYTNYTNTCNGAYCARGGNATHGTNTCNYTNGCN YTNGARMGNCARAARTCNAARATGGGNCCNACNMGNCCNTCNAARAARGARAAYATHGAR AGYYTNCCNYTNAAYYTNGCNCAYAAYTAYGARAGYYTNGGNAAYACNACNMGNTAYAAY GTNTGYCCNGGNGTNAGYTCNGGNCAYACNATHAGYMGNACNAARGAYGARTTYAAYGAY GARGTNCAYCARMGNMGNGTNCCNGCNACNGAYGARTTYMGNTGYCARMGNGAYGARYTN AGYNNNYTNTGGGTNGARCARGAYGTNYTNMGNAARMGNATGGARCAYAARTGGAARTCN TAYTAYGARAAYCARCCNGTNCCNGCNGCNAARCCNCCNCCNGCNAARCCNAARCCNAAR CARAARCARAARCCNAAYGARACNCCNAAYAARACN---CCN---TTYGAYGAYGARCCN GARATHGTNTTYGTNACNCCNCCNYTNACNCCNCCNCCNCARGARMGNGARYTNGTNGAR YTNCCNCARGCNTTYGARMGNGAYGAYGARTTYTGGGGNTTYTAYGAYCAR--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------AARTCNACNACNTCNACNATHAAYTTYGTNTGYAGYTCNTGYGAYTTYGTNGTN GAYTGYCAYTAYCAYGGNAARMGNCCNCCNTTYGCNAARCAYGTNGTNYTNCAYGARGAY TGYTAYGTNATGAARGAYCCNTTYTCNACNGCNGGNGGNTTYATHAGYGTNGGNGCNGTN TGYTCNYTNTGYAARGARAGYGTNTGYATGTCNAAYAAYTGYAGYYTNTAYTTYACNCAR MGNTTYTGYYTNMGNTGYGCNGCNGAYAAYYTNACNGARTTYCCNYTNGARYTNCARGGN TTYYTNAGYTTYYTNGGNATHATHATHTTYATGATHATGACNTCNGARATHGTNTCNCAY GGNGCNMGNTAYTCNTGGGGNTTYGCNTTYGCNTTY------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------TTYGAY GARGAYYTNAARAARYTNCARCARTCNTTYCCNAAYCARTCNTCNMGNTTYTGGAAYACN GTNGCNGCNTCNGGNMGNCAYGTNTTYMGNCARGARGAYCCNTGYTAYCCNAGYGTNATH YTNATHGCNGCNCAYAGYAARAAYCARAARYTNAAYAGYTGYYTNGCNAARMGNATHGCN ACNATHTTYTCNCAYTCNMGNGGNGTNCARTCNGARAGYTCNCARACNGAYGTNGARGAR TTYMGNCAYYTNGARCCNGARAARCARAARYTNGARYTNGAYTCNATHYTNCARMGNGCN TTYCAYCAYGCNGGNGARAARGCNTTYGTNATHGAYAAYGTNCAYTCNYTNTCNCCNAAR GCNGCNGTNYTNYTNCAYGGNATHTGYGAYGGNGAYAAYGCNCCNTAYAARGAYGTNATG ATHYTNYTNACNTTYCAYGTNCARGAYGAYACN---------MGNATHGAYCAYCAYAAR CARGTNGARGAYYTNYTNACNMGNATHTGGGCNMGNGGNYTNGAYATGGAYAARYTNTCN GCNATHATGAGYMGNGTNGCNAAYAAYGCNATHTTYYTNAAYCCNGARACNGARAGYACN ATHMGNAAYCAYTGY--------------------------------------------- ------------------------------------------------GARTGYTCNAGY GAYYTNGARGARTAYATGYTNGARYTNYTNGAYGGNTCNAAYCCNAARGTNMGNTTYTTY YTNCARGAYYTNAARGAYMGNTTYAAYAAYAARGGNAGYAARGGNAGYGTNCARGTNTAY MGNAARGARAARACNCCNGAYCCNAARGARGARAARYTNAARAGYAARAGYGCNAAYCAR MGNAAYGCNAARAAYAGYTCNTCNACNAARCCNGTNGCNAAYGGNAAYGTNTCNAGYGTN GARYTNAARGAYCARAARGCNCCNATHAAYCCNCAR------GTNGAYTCNTCNAARTCN TCNGGNGARATHGGNATHGGNGCNAARAARAARTCNAARTAYGTNCCNYTNTTYAGYAAR GARGGNCARGARAARTCNGTNATHCARYTNTCNGGNMGNCAYAARTGYGAYTGYCARGCN GCNAARCAYAARYTNATHAAYAAYTGYGTNCARTGYGGNMGNGTNGTNTGYGCNCARGAR GGNCCNGGNCCNTGYATHTAYTGYGGNGCNYTNGTNTGYACNCCNGARGAYATGGARGTN YTNGARMGNGGNTCNMGNAARGCNGARMGNYTNMGNGAYCARYTNATGAARGARGGNGTN AARAARTCNAARGGNYTNAGYGARGCNGGNCARTCNYTNYTNCCNATHGGNTTYAAYAAY CARACNAARGARAARGARGARAARGCNYTNAARCAYMGNGAYAARYTNYTNGARTAYGAY MGNAAYAGYGARMGNMGNACNCARGTNATHGAYGAYCARTGYGAYTAYTAYGCNACNGAY TCNAAYMGNTGGYTNAARAARGARGAYMGNGARAARYTNMGNAARMGNGARGARGARYTN MGNGARTCNMGNCAYGGNTCNMGNMGNGAYMGNAARATHACNTTYGAYATHGCNGGNMGN AAYATHAARGTNYTNGAYGCNGARGARGAYACNGGNAARGCNATGTAYAAYATGAARGAY TCNGTNATHCARGARGTNCAYTAYGGNAARAARYTNCCNAAYGGNAAYACNCCN---GAY YTNGTNAAYCCNTTYATGGTNTCNGARCCNCCNACNTTYYTNGAY---TCNGGNGCNYTN CARTGGGGNCCNAGYAARTCNAAYCCNATHTCNAGYGAYCAYAAYCCNCARTCNTCNTCN MGNMGNATHCARGAYMGNGARYTNCARGARATGAGYGAYGARGGNATGTGYATGAGYATG CAYCARCCNTGGGCNTCNYTNYTNATHTAYGGNATHAARATGCAYGARGGNMGNTCNTGG TAYACNGCNCAYMGNGGNMGNYTNTGGATHGCNGCNACNGCNAARGARCCNGTNMGNGAR GARATHGAYGARYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------TGGAARAARMGNTGY AARATHTGGGGNTAYCCNGAYGGNTCNATHTAYAGYAGYACNGCNACNGCNCCNGCNCCN TCNAARAAYTTYGTNCARATHTAYATHACNGAYTCNGARGTNATHTTYMGNATHTGGAAR ATHYTNCCNCCNACNMGNGCNGAYGCNAAYCARATGCCNMGNCARATGGTNGGNMGNTAY AARGARTTYYTNGAYGAYGARAARTTYMGNGGNGARYTNGARATHAAYATGGGNGTNAAY GARYTNTAYTTYGTNGAYAARYTNATHGCNGGNCARATHGAYTAYYTNAAYMGNATGCCN AARGAYGTNYTNGTNAARATHYTNTAYCAYATGGAYYTNATHACNATHGTNAARYTNGGN YTNATGAAYAARTAYYTNTAYGARGTNTGYAGYTGYAAYGARYTNTGGTCNAARATHTAY AARGAYTTYAAYGARTCNCCNGTNACNCARGARYTNYTNATGYTNGTNGAYCARAARGGN TGGAARGARGTNTTYTTYATGAAYAARYTNCARYTNCARATGATGATHMGNMGN---AAY CARGCNCCNAGYAARGAYAAYGGNMGNTTYTAYTAYGGNAAYTTY--------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ACNMGNCARGARGCNGARGARATHTGY MGNGCNGARAAYYTNGTNGAYTTYTAYTTYGAYTCNTGYGTNTTYGAYYTNATGGCNACN GGNGAYGARAAYTTYACNATGTCNGCNATHMGNGCNYTNCARGAYGTNYTNAARYTNCAR CCNCAYGARGCNCARACNATGGARAAYMGNAGYAGYYTNGARACNTAY------------ ---------ATGGCNTCNCCNGTNTAYATHTGGTTYACNACNGARGTNATHAARTGGMGN AGYYTNGCNGCNTCNYTNTGGTCNATHATHTGYYTNCCNGCNYTNATHTTYGTNATGTCN YTNYTNYTNAGYATHTCNTTYTCNCAYCCNYTNGTNTGGATHTCNGAYGCNGTNAAYGCN ATHYTNTCNYTNCARTTYYTNTAYACNTTYYTNACNTTYATGATGGCNATHATHACNGTN ACNTGGTTYTCNYTNTCNTAYTTYTGYGTNAARCARGARATHGAYAGYTCNMGNTTYTCN TGYGTNYTNGGNYTNTTYMGNTGGTCNMGNYTNCCNYTNYTNGTNATHTGYYTNGTNAAY GGNTCNGTNTGYGGNTGGAGYYTNGCNAARYTNGCNGGN---GARCAYYTNACNTTYTAY YTNAAYACNCCNGARTTYGARAARACNGTNYTNAAYGARGAYTGYYTNTTYATGAAYGGN TGYGGNATHTTYACNGGNTTYTGYTAYTAYTGGCAYTTYTTYATHAAYCAYGARTAYTAY YTNAGYTTYCCNAGYYTNCARMGNYTNAARYTNTTYCARGTNMGNAGYGARTCNAARACN ATGGCNGCNGGNGTNGCNTGGMGNACNYTNCAYGTNATGAARTAYTAYTAYATHATGTAY TTYYTNTTYGGNTCNYTNCCNMGNATHTGGATHTGYTCNTCNTTYGGNATHAGYGARGAY ACNGAYTCNGCNCCNYTNGAYTCNATHGTNGGNYTNTTYAGYYTNTCNYTNTTYTGGAAR ACNTAYYTNYTNTCNTTYATGTAYACNTTYACNYTNTCNTTYACNATHGTNATGACNMGN ATHTTYCAYACNGARCAYYTNGARTTYCCNGTNATHAGYATHATGGARGAYTCNAAYGAY AARACNYTNCCNGAYGGNYTNTCNTGYACNTAYGCNCCNYTNYTNCARCAYCAYGCNTTY TAYGAYYTNTCNTGYYTNAGYAARATHACNTCNCCNMGNYTNCARGARGTNYTNAGYYTN AGYCARCCNGGNGGNCAYCCNAARATGTGGATGGCNGTNAGYGGNTCNGCNATHAGYGCN ATHMGNGARYTNAGYAAYCARGTNAARGARGARAAYTGGTCNATHATGTCNAARGTNCCN GTNGGNGGNCCNAAYGGNAAYGGNTTYTAYACNGCNGGNGCNACNGGNGAYMGNATGGAY TCNTCNYTNGTNTAYMGNGGNGAYGTNAGYAARGGNGGNGTNCAYCCNGARACNGARCAR GTNGARAARACNAGY---ATHGTNTCNCARTGGATHAGYGGNYTNTCNTTYGTNCCNYTN YTNTCNCARATGATGGARCARAGYCARGAYGTNAAYAGYMGNMGNYTNTTYGCNTCNTGY CARGTNCARATHTGGGCNATHGARAGYYTNTCNCAYATHGCNGCNMGNGCNTAYACNGAR GAYMGNTAYGGNATHGTNCARAGYTCNYTNCCNYTNATHTTYYTNTCNYTNYTNGARYTN CAYGARTCNYTNGARAARCAYTTYAARYTNAGYACNTCNTCNMGNMGNACNAAYGGNTCN YTNCAYTCNCCNAAYGAYTGYGTNATHMGNTAYAARYTNCAYTCNGTNYTNAARGCNGCN YTNTAYMGNATHYTNAAYACNTAYAARGCNCAYYTNCARGAYATHAARYTNACNCCNGAR GARATHMGNAARYTNACNCCNTTY---------------TTYGARGCNGTNCCNTAYACN TTYTAYGARGCNGGNACNGCNTAYTTYTGGGTNCAYTAYGGNYTNGTNATHYTNGGNTTY YTNGTNGCNGTNGTNACNTGYATHGCNCARTGGMGNAARCCNGCNCCNTAYGGNAARCAY GARTCNTCNGCNGARGAYTGGGGNCCNYTNATHCCNCARMGNYTNGCNCAYTTYYTNTCN GAYGCNATHCCNGGNGTNYTNATGTTYTCNYTNGTNTTYTTYYTNTAYAGYMGNGARGAR AGYGAYAARAARGCNATHAAYTAYGTNTTYTTYGGNYTNTTYYTNGTNCAYACNGTNCAY MGNGGNATHATHCAYCCNYTNGTNATGMGNTAYAARAGYGCNMGNGTNCCNYTNGGNATH TGYYTNGGNGGNYTNGTNCCNAAYGTNYTNTAYCARTGGYTNATHGCNAAYCAYATHGGN GTNGCNCARTAYGGNGCNTCNTAYCCNTAYGAYCCNMGNTTYATHGTNGGNGTNYTNYTN TAYATHGTNGGNTTYGTNGTNAAYMGNTGGGCNGAYTGGAARYTNMGNTCNYTNMGNCAR AARAARGGN------------------AGYAARGGNTAYTAYATHCCNCAYGGNGGNYTN TAYAAYTAYGTNTCNTGYCCNAAYTAYTTYGGNGARYTNGTNATGTGGACNGGNTGGGCN YTNGCNACNTGGTCNYTNTCNGGNTTYGTNTGGGCNTGYTTYGGNGCNGCNACNTTYYTN GCNMGNTCNMGNCAYAAYCAYCARTGGTAYMGNGAYCAYTTYGARGAYTAYCCNAGYGAR MGNMGNGCNYTNATHCCNTTYATHTTYTCNGAYGCNGGNTGYGAYCAYAARGARGCNYTN TCNMGNACNGCNAARYTNGTNATHAARGCNTCNGAR------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TTYATHYTNCAYCCNTCNGGNACNCAYTAYATGCCNATHTCN GTNCAYAAYTCNGAYATGGGNAARYTNTTYGARGCNACNGGNGARCARGAYTCNATGCCN GTNTTYCAYCCNATHAGYATHCCNGTNCAYTTYMGNMGNCCNGTNATH------------ ------------------------------------------------------------ ---------------------ATGCCNTGGTGGGCNGTNGTNTCNGGNTGGGCNYTNGCN GTNGCNTCNGGNYTNGCNGTNGTNTAYGGNGTNTAYGGNGAYGTNACNGGNGAYAAYCAR AGYAGYACNCARGTNGCNGCNYTNTAYAAYGCNGTNTCNMGNTCNGTNTGGGGNGCNTGY GTNTCNTGGGTNATHGTNGCNTGYGCNTGYGGNTAYGGNGGNCCNGTNAAYGCNYTNYTN TCNTGGTCNCCNTTYGTNTTYYTNGGNMGNYTNACNTAYATGACNTAYYTNATHCAYYTN ACNGTNGGN--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------GAYGAYTCNMGNGAYAAY TTYGARMGNGGNCARACNGARGTNTTYGARGTNAAYGGNYTNGAYGTNGGNCCNYTNACN MGNYTNCARATHGGNCAYGAYAAYTCNGGNCCNGGNGCNGGNTGGTAYTGYGARAAYATH ACNGTNAARAARTTYYTNCAYCAYGARGAYATHGTNGCNGTNYTNAARAARYTNAARAAR AARGGNAARTCNAARCAYCARAARAARAARMGNYTNTCNCARAARYTNAARGARCARMGN YTNAARGARCAYAARGARGAYGARGARGARTCNGARGARGARGARAGYGAYGARGAYGAY AARGAR------TAYAARAAYGTNTTYGAYGGNGAYGGNAARGTNAGYAGYGTNTCNMGN GTNGAYATHGCNGGNATGACNTAYYTNAARACNGGNCCNGAYACNYTNGARYTNTCNTCN CAYGGNCAYATGAARCAYGCNGCNAGYMGNGCNGTNCARAARAGYYTNAGYATHGTNGCN GCNAARCAYAARMGNGGNAARMGNACNMGNAARGGNAARCAYCARCAYTGYYTNTTYTTY GGNMGNTTYGGNAARTGYCARMGNGGNAAYGCNTGYCCNTTYATHCAYGAYCCNGAYAAR GTNGCNATGTGYTCNMGNTTYYTNMGNGGNCARTGYGAYACNTCNACNTGYCCNTTYTCN CAYGAYGCNTCNGAYCAYAARATGCCNGTNTGYYTNTTYTAYYTNMGNGGNYTNTGYTCN MGNCARGAYTGYYTNTAYYTNCAYGTNAARGTNAGYCCNGAYGCNCCNGTNTGYCARAAY TTYYTNCARGGNTTYTGYATHYTNGGNMGNAARTGYAARAAYYTN--------------- ------------------------------------------------------------ ------------ATGCCNAGYTTYMGNATHGARACNAAYYTNTCNAARGAYCARATHCCN GARAARTTYYTNCARGARGCNACNAAYYTNYTNTCNGCNGARYTNGGNAARCCNGGNACN TAYGTNTGYGTNCARGTNTGYCCNGAYCARGTNATGAGYTTYGGNGGNACNACNGARCCN TGYGCNAAYATHTCNYTNCAYTGYATHGGNGTNGTNGGNCCNGARAARAAYMGNYTNYTN GCNCCNGTNYTNTCNAARTTYATHGARCARCARYTNGGNATHAARCARGAYMGNTTYTAY ATHAAYATHTTYGGNGGNATHTCNYTNTCNGAYAARMGNGTNGARGARATHYTNGGNGTN GCNAARTAYTGGTGYGTNTCNAAYGGNATHGCNYTNMGNTCN------GARGARCCNCAR TCNTCNAARTTYGTNTGYGCNCCNTTYGCNYTNTTYCCNACNGTNGTNCCNTCNGTNGTN YTNGCNCARGCNAARGGNACNATGAARCAYTTYAAYMGNYTNATGTTYMGNGTNGGNATG GAYCAYCARTTYYTNGARCARTCNYTNAARAAYGTNATHGARGTNGAYGAYTTYATGTGY AARYTNTGGAAYGTNTAYTGYAARTCNMGNGARAAYGGNATHAARCARCCNATHATGYTN GGNYTNTTYMGNAAYGAYTTYATGGTNAAYTGYTCNGAYGGNACNTGYTGYAAYCCNGAR YTNMGNACNGAYTGYYTNCARYTNAARCARATHGARTTYAAYACNATHGCNTCNGGNTTY GCNGGNYTNATHCAYMGNGCNTGGGCNYTNCAYMGNATGACNYTNGGNYTNGCNGGNAAR GARTTYACNTCNAGYCARGCNCCNGARAAYMGNCCNGCNYTNGGNYTNGCNTCNGGNATG ATHAARGCNTGGGARYTNTAYGGNAAYCCNAARGCNGTNATHGTNTTYATHGTNAGYTCN GAYGARMGNAAYYTNTTYGAYCARMGNACNYTNGARTTYTGYGTNTAYGARGTNAAYGAR CARGTNMGNGTNYTNMGNAARACNYTNATGGAYTTYAGYGTNMGNGGNAGYYTNGAYAAR GAYAGYAAYYTNATGATHGAYGGNGAYGARGTNGCNGTNGTNTAYTAYMGNGAYGGNTAY ACNGCNGAYAAYTTYTCNTCNCARAARCARTGGGAYGCNAARYTNACNATHGARYTNTCN MGNGCNATHAARTGYCCNTCNATHCARCARCARYTNGTNGGNGCNAARAARATHCARCAR GARYTNGCNMGNCCNGGNGCNYTNGARMGNTTYATGGAYGAYCCNGARATGATHAARGCN GTNMGNGARACNTTYGCNGAYCARTTYAGYYTNGAYYTNGGNCCNGAYGGNGAYAGYGCN GTNTCNYTNGCNATHAAYTCNCCNGARAARTTYGTNYTNAARCCNCARMGNGARGGNGGN GGNCAYAAYATHTAYGGNGAYAAYATHCCNAARTTYTTYAARGARCAYGGNAAYTCNAAR GARMGNAAYGCNTAYATHYTNATGGARMGNATHTTYCCNYTNCARCARCARAAYTTYYTN ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------GARAGYTAYGTNGAYGARAGYATGAARYTNGARTGYTCNGAYACN GARGARACNGGNAGYATHGARMGNTTYGTNAAYGTNGTNTCNGCNMGNACNGCNGTNGGN CAYGAYAARGARGGNAARGTNCAYATHGTNCARGTNGAYGGNTGGTCNGAYCAYCARGGN GTNAAYYTNCAYGARTTYGCNGAYYTNYTNATHGAYYTN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGGCNGARCARTGYAARGARTTYYTNTCNAARACNTTYTGYTTYAGY TCNATHTCNTTYAAYGTNYTNYTNGCNAARGARTGYGGNATHTTYAARACNYTNYTNACN GCNGAYMGNCCNYTNACNTCNCARGARATHGCNAARGAYAAYAAYATHAARGARMGNTAY ACNMGNGARATHYTNGGNTGYYTNTCNAGYGGNAARYTNGTNMGNGTNCAYAAYGGNAAR GAYGGNGGNTTYATGTAYGAYATGGARGARGARACNAARGARTGYYTNGAYAARGGNTGY TCNATHGARTAYYTNAAYTTYACNAARATHYTNATGGAYMGNTAYCARAARATHAARGAY AGYATHCARATGGAYAARCCNGGNGCNGTNMGNTAYGGNGAYACNTAYTTYGAYGCNGCN GARGARATHAARGARAARACNGCNAAYGGNACNGCNGAYMGNYTNGTNAAYGAYGTNCCN GGNYTNAARGARAARYTNGARGCNGGNATHGAYGTNATHGARTTYGGNTGYGGNMGNGCN YTNGTNYTNTCNATHYTNGCNACNAARTTYCCNAARAGYACNTTYACNGCNTCNGARATH TGYCCNGAYYTNYTNGARACNATHMGNCARAARTTYAGYCAYATHCCNAAYYTNTGYTTY AARYTNGTNGAYYTNTGYGCNGCNGARCARATHGTNGAYCAYMGNTAYGAYTGGGCNYTN TCNATHGAYATHGTNCAYGAYYTNCCNCAYCCNGGNCARGCNYTNAARGCNGTNMGNGGN ATGGTNAARGAY---GAYGGNGTNTAYACNTTYGTNGAYATGGCNGGNACNGGNAGYCAY ATGGCNGAYGTNGGNGAYYTNTCNGCNGCNGCNYTNTAYAGYYTNAGYACNTTYYTNTGY ATHCCNGARAGYTTYCARCARGARGAYACNGARGCNCAYGGNGCNTGYTGGGGNYTNGAY ACNGCNYTNGGNTTYGCNAARGCNGCNGGNTTYGAYACNCARGTNGTNCCNTGGGARTCN AARACNGTNYTNTTYATHGCNAARGAYGCNGARAAYCCNCCNACNTAYACNGARMGNAGY AAYATGGCNCCNGARGARGGNGCNACNCCNCCNGAYTAYAAYGCNGCNGCNTAYCARGAR CCNCCNCCNTCNTAYGAYTCNYTNTTYGGNMGNGTNAARAARATGAARTCNGARTCNTCN GGNACNATGGAYTTYTTYAARACNYTNGTNACNGTNYTNYTNAGYACNATHGGNTTYACN ATHYTNATHGGNYTNTTYYTNGCNATHCCNATHTCNATGATHGTNATGGGNGCNYTNTAY YTNGAYGAYTGYCCNGCNGARMGNATGATHCCNATHTAYYTNATHGTNGCNGGNAGYTTY GGNTGYGCNAARAAYYTNTTYAGYYTNATHCARMGNTGYMGNAARTCNMGNGARGARMGN GARGARGARACNACNAARGTNAAYCCNGTNTCNAGYYTNGTNGAYTGYTTYYTNTTYGCN TGGTTYATHGCNGGNTGYGTNTAYATHTAYMGNACN---AARGAY------GARTTYCAR GCN---CAYGAYCCNGAYTAYTGYGAYTAYACNYTNTAYTGGTAYTCNTTYTGGATHACN ACNTCNGTNTAYATHGTNATGGGNGCNAGYTGYYTNTGYATHTGYTGYATHGGNTGYATH GCNGCN---------------AGYCAYYTNATHTGYGGNTCNYTNAARAARACNGARAAR TTYATHGGNGCNTGYATHATGGGNAARTGGATHYTNTCNCCNCARTTYATHGARGAYAGY CAYCARATHGGNATGTGGYTNGARGARGARAAYTAYYTNTTYMGNGTNGARAAYAARGAY CCNYTNAARGAYCARYTNGCNAARACNGCNMGNMGNTGGMGN------------------ ------------------------------------------------AAYAAYGTNAAR AAYTCNYTNGTNYTNYTNTAYACNYTNACNYTNYTNGARACNTGYGTNAARAAYTGYGGN AARMGNTTYCAYGTNCARGTNGCNAAYAARGAYTTYYTNCAYGAYATHGTNAARATHATH GGNCCNAARAAYAAYCCNTCNGARCARGTNCARGARAARGTNYTNAGYYTNATHCARACN TGGGCNGAYGCNTTYMGNGGNCARCCNGAYYTNAARGARGTNGARAARATHTAYATHGAY YTNAARAGYAARGGNATHGARTTYCCNATGACNGAYYTNGAYGCNYTNGCNCCNATHCAY ACNCCNGCNMGNAGYGTNCCNGARCCNGARCARCCN------------------------ ------------GCNTTYCARCCNCCNCARCARCCNGTNTCNCCNCARCAYCARCARGTN GCNCCNCARCARMGNCCNCARGGNCARGGNCARGGNACNGGNCCNGTNAGYGCNGARCAR YTNGCNAARYTNMGNAGYGARYTNGAYGTNGTNCARGGNAAYYTNAARGTNTTYGGNGAR ATGYTNACNGARATGACNCCN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------CARTGGCCNATHATHTAYGCNATHGARTAYAAYATHAGY TTYYTNGGNTTYGARAARYTNCAYCCNTTYGAYGCNGGNAARTGGGGNMGNGTNCAYGAR TTYYTNAARGARGCNGGNATGYTNTAYGAYCAYACNACNATHAARCCNATGGARGCNTCN CARGCNGAYYTNATGGTNGTNCAYCCNAARAARTAYATHGAYAGYYTNAARTGGAGYATH AAYGTNGCNGGNATHACNGARGTNCCNCCNGTNGCNYTNYTNCCNAAYTTYGTNGTNCAR MGNAARGTNYTNMGNCCNTTYMGNTAYCARACNGGNGGNACNATHYTNGCNGCNAARYTN GCNGTNGARMGNGGNTGGGCNATHAAYATHGGNGGNGGNTTYCAYCAYTGYTCNGCNGAY AARGGNGGNGGNTTYTGYGCNTAYGCNGAYATHACNYTNGCNATHAARTTYCARATGGAR MGNAAYCCNGCNGTNAARAARGCNATGATHATHGAYYTNGAYGCNCAYCARGGNAAYGGN CAYGARMGNGAYTTYATGGGNAAYGAYGAYGTNTAYATHYTNGAYGTNTAYAAYMGNGGN ATHTAYCCNCAYGAYGGNTAYGCNAARMGNGGNATHAARMGNAARGTNGARYTNCCNTTY TAYTGYGARGAYGARCARTAYYTNGAYYTNGTNMGNACNAAYGTNGARGGNGCNYTNAAY GARTTYACNCCNGAYYTNGTNGTNTAYAAYGCNGGNACNGAYATHYTNGAYGGNGAYCCN YTNGGNTGYYTNAGYATHTCNCCNGARGGNATHATHGARMGNGAYCARATHGTNTTYGAR AARATHMGNGCNMGNAAYATHCCNATHATGATGGTNACNAGYGGNGGNTAYCARMGNACN ACNGCNMGNATHATHGCNGAYTCNATHYTNAAYYTNMGNGCNTTYAGYYTNATHCCNTGY GARGARGCNGCNYTNGTNGGNMGNGAYTTYYTNAGYYTNAARCAYTTYAARGCNGAYGAR ATHAARCARYTNYTNTGGACNGCNAARGAYYTNAARACNMGNATHAARGAYAAYGGNGAR ATHTTYCARCCNYTNAARGGNAARACNGCNGCNATGATHTTYCARAARMGNAGYACNMGN ACNMGNYTNTCNACNGARYTNGGNTTYGCNAARYTNGGNGGNCAYGCNACNTTYYTNGGN TCNGARGAYATHCAYYTNGGNGTNAGYGARAGYGTNTCNGAYTCNGCNMGNGTNYTNACN MGNATGGCNGAYGTNATHYTNGCNMGNGTNTAYGARCAYGAYGTNYTNGARACNYTNGCN GAYGGNGCNTCNGTNCCNGTNATHAAYGGNYTNTCNGAYYTNYTNCAYCCNYTNCARATH ATGGCNGAYTTYATGACNYTNCARGARCAYTTYGGNTAYYTNMGNGGNTGYAARATHGCN TGGGTNGGNGAYGGNAAYAAYATGYTNCAYTCNTTYATGTAYGGNTGYGCNAARYTNGGN ATHGAYYTNAGYGTNGCNACNCCNGCNGGNTAYGARCCNGAYACNGAYATHACNYTNGAR GCNATGAARATHGCNGGNAARACNGGNGCNTCNATHAARATGAGYAAYGAYCCNYTNGAY GCNGTNTAYMGNGCNGAYGCNGTNGTNACNGAYACNTGGGTNAGYATGGGNCARGARGAR GARAARGTN---AARMGNATGGCNGAYTTYAARGGNTAYCARGTNAAYMGNAARATGATG AARGARGCNGGNGCNGAYTGGGTNTTYYTNCAYTGYYTNCCNMGNAARCARGARGARGTN ACNGAYGAYGTNTTYTAYGGNCARGARTCNYTNATHTGGCARGARGCNGARAAYMGNATG TGGACNGTNATGTCNGTNATGYTNCAYGTNYTNCAYCCNTAYGARCCNACNATHCCNATG CCNAARTAYGTN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARAGYGTNGGNATGGAYGCNGGNMGNMGN GARCAYACNYTNGTNATGMGNYTNACNACNAARGARCARGARYTNCARGARTGYATGAAY CARATHCARGARATGAARCARGCNCARACNCARAAYACNGCNCARYTNMGNTCNYTNYTN GAYCCNGCNATHAAYYTN------------GTNTTYCARMGNATG--------------- ---------------------------------------------------TCNAARGAR ATGGAYGARCAYAARGARAARYTNAARCARAARCARAAYGARYTNAAYGCNTGGAARTTY ACNCCNGAYAGYCARACNGGNATGMGNYTNATGGTNAARTGYMGNATGYTNYTNCARGAR AAYGGNGARYTNGGNAARATHATHTCNACNGGNMGNACNGCNAARYTNGARGGNGARATH TCNYTNCAYAARGCNYTNGTNGGNGARATGAARAARAAYCARAARGARYTNGAYGARTTY GTNGGNGARYTNGARGARGAYGTNGARGGNATGCARGGNATGATHTTYATGYTNCARCAR CARYTNAARGARGCNMGNGARCARATHACNMGNYTNCARCARGARAAYGARCARYTNMGN ACNYTNCARYTNCCNACNGARCCNGAYCCNGGNGGN------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYTCNAAYCAYGAYGARGAR GARGARTCNGGNACNTGGATHCARTGYTCNTCNACNAARTGYGGNAARTGGMGNTAYGTN GCNGAYATHTCNGARCCNACNAARGTNCCNGARCAYTGGGARTGYAGYATGAAYTCNGAY AARGAYCAYAAYTCNTGYGARGCNTCNGARATHGARTAYGAYGARAGYGARCAYATHATG ACNAARTAYACNYTNGGNTCNGTNGTNTGGGCNAARATGGAYGGNTTYCCNTGGTGGCCN GCNATGATHGAYTCNGAYCCNGAYTAYGAYACNTAYTTYGARYTNCCNACNTCNACNAGY ATGATHCCNTAYATGTAYCAYGTNACNTTYTTYGAYGARCAYGTNTCNMGNGCNTGGATH MGNTCNCAYTTYATHGCNCCNTAYTAYTCNAARYTNCARCCNAARACNACNYTNTCNMGN AARTCNCARTCNAAYMGNAARGARYTNAARATHGCNATHTCNAAYGCNGARATHGTNATG CAYYTNCCNYTNCARGARMGNYTNGAYCARTAYAGYTTYYTNAARMGNTTYTCNAAR--- ------------------------------------------------------------ ------------------YTNGARGARTTYGTNATGAARCCNGCNCCNCARGGNGTNACN ATGAARTGYMGNATHACNMGNGAYAARAARGGNGTNGAYMGNGGNATGTTYCCNACNTAY TAYYTNCAYYTNGARMGNGAYGAYGGNAARMGNGTNTTYYTNYTNGCNGGNMGNAARMGN AARAARAGYACNACNTCNAAYTAYYTNGTNTCNATHGAYCCNACNGAYYTNTCNMGNGCN GGNGARTCNTTYGTNGGNAARYTNMGNTCNAAYATGYTNGGNACNCARTTYACNATHTTY GAYAGYGGNGARAAYCCNAARAARGGNAAYACNGAYACNTCNMGNMGNGARGTNTGYGCN GTNATHTAYGARACNAAYGTNYTNGGNTTYAARGGNCCNMGNAARATGACNGTNATHATH CCNGGNATGAAYYTNGAYCAYGARMGNGTNGARATHMGNCCNMGNTCNGAYCAYGAYGGN YTNATHGARMGNTGGAARMGNAARAAYATGGARAAYATHYTNGARYTNCAYAAYAARACN CCNGTNTGGAAYGAYGAYACNCARTCNTAYGTNYTNAAYTTYCAYGGNMGNGTNACNCAR GCNTCNGTNAARAAYTTYCARATHGTNCAYGAYAAYGAYGTNGAYTAYATHGTNATGCAR TTYGGNMGNGTNGCNGARGAYGTNTTYACNATGGAYTAYAAYTAYCCNYTNTGYGCNYTN CARGCNTTYTCNGTNGCNYTNAGYAGYTTYGAYAGYAARYTNGCNTGYGARYTNACNGCN ATHYTNMGNACNYTNACNAARTGYGAYTAYCARMGNGAYGTNGTNGCNATHMGNAAYYTN ACNTAYGARATHYTNACNYTNTCNACNAAYGGNTCNAAYATHAARCCNGCNYTNCCNACN GTNGTNAARYTNYTNGCNCAYCCNGAYGCNTTYGTNAARMGNGTNACNGGNGARATHATH GCNATHCAYGCNGARGARAGYCARGAYATHTCNYTNYTNGGNATHAAYACNYTNGTNCAR GAYTGYAARGAYGTNAAYCCNGTNGTNMGNGGNGTNAGYTTYMGNATHYTNGGNTCNATH AARGCNAAYGCNGTNTCNGARGTNYTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------------ATG GCNTAYGARCARTCNTGGGARGTNGTNGGNAARGCNAARAARGCNAARGGNAAYTCNAAR AARYTNTCNGCNGCNAARGARAARGARATGYTNGAYAARATGCCNMGNATHGCNAAYGTN GAYCCNGTNCCNYTNGAYGAYACNATGTAYTCNGTNTTYGARGAYMGNGARCARMGNGCN MGNGARAARGCNGCNGCNGCNAARGCNGARGCNYTNCARAAYCARAAYGGNCAYAARAAR GCNCCNAARAARAARAARCCNGARGARCCNAARAARCARAARCARAGYCCNGTNCARYTN CCNGTNGCNYTNTCNAARYTNGAYTAYAARGAYYTNGARAGYGTNYTNAGYCARTCNCAR TCNTAYTTYCCNACNCAYCCNATGGTNTGGYTNAARGAYYTNGCNTCNTAYYTNAAYATH CARYTNGARAAYACNATHGARCARGAYCCNGCNTAYAARGGNAARTCNGTNGGNTTYCCN YTNGAYGCNGTNCCNTCNAAYTGYGCNAAYGTNYTNCAYTCNTTYATGAARAARTTYTCN CARCARACNYTNGAYAGYATHTTYYTNTAYGGNATHCARACNATGYTNCARGARTCNGCN AARGGNATHCCNGTNCAYGGNTAYAARYTNTTYYTNCARYTNYTNTCNTAYACNAARCCN GAYATHGTNGTNGAYAARYTNCCNCARTAYYTNGARYTNGTNAARYTNCAYCAYAAYAAY CCNTCNAARTGYYTNTCNATHYTNTGGGCNYTNGGNCARTGYGGNTAYAARAAYGTNAAY TGYGGNYTNAARGTNTGGYTNGAYYTNATGYTNCCNGCNYTNGARGTNMGNCARGTNGCN CAYTAYCCNGTNGARTAYYTNGARACNYTNATHAARTCNAAYAARACNACNAAR---AAR ------------AGYTAYGGNATHGTNACNYTNAARGARTAYTTYCARGTNYTNGAYGTN TTYTTYACNCCNCARTTYACNYTNGCNAAYGAYYTNMGNAARMGNYTNACNGTNTGYTAY CCNTTYATHAARAARYTNGCNTAYGGNGARGARCCNTCNCAYAAYYTNMGNACNTTYTTY CCNTCNTAYYTNACNMGNTAYACNTCNACNAAYTCNCARCCNYTNAARCAYGARYTNYTN GARTGYATGACNCAYTGYYTNATHACNGAYAARCARTCNTAYAGYGTNTGGTGYCARYTN TAYACNAARCAYYTNGTNGCNTCNAGYCAYYTNYTNGARCAYATHAAYCAYAAYTGGGGN AARYTNTCNTCNAARTTYGAYAARAARGTNYTNATGGARACNYTNMGNTCNTTYTCNGTN ACNAAYGARGARYTNGARYTNCARAGYAARGGNAARYTNAAYGGNYTNAARYTNTGYCAR GAYACNACNAARGAYYTNMGNYTNAARYTNACNGGNACNCAYTTYCCNTGGAGYYTNYTN GTNTTYTTYYTNGTNTCNGTNTTYGCNGCNATHGTNGTNTAYGAYATHATHTCNAGYCCN AGYTTYMGNYTNTCNAARACNATGCARTTYYTNGARCAYTAYGGNATHYTNGCNYTNYTN GARAAYACNTAYCARTGYATHAAYAAYGTNGTNACNYTNTCNATHAAYTGGYTNAARGTN AAYTTYCCNATHTTYTAYACNTCNGTNMGNGAYACNGTNGTNCCNTTYATGATHYTNGTN TGGGARACNTCNMGNGAYTTYGTNATHAAYGCNGARGTNGTNTCNMGNCCNTAYMGNGAY YTNATGGTNGTNAARGCNATHCARYTNTAYAAYTGGGTNTAYGARYTNTCNCCNGARTTY TGGGTNMGNTGYGGNGARYTNTCNTGGYTNGCNTGGGARATHYTNAARGAYTAYTCNTTY MGNATHTGGAARCAYATGGTNGTNTAYGCNGGNGARGCNGARCAYTGGYTNACNGARCAY GTNYTNACNGGNTCNTTYTCNAARCARACNYTNAARGAYACNGCNATGTGGGGNGTNGAR AAYGTNCARAAYTAYACNTCNTTYGTNGTNTCNTGG------TTYTTYGARGCNYTNGTN CAYTCNATHMGNTCNTCNTGYTTYCARTTYYTNGAYTTYMGNGARAARGTNTCNYTNMGN GGNTTYYTNGCNYTNGAYGTNGAYGGNGARCAYCARCAYCAYTTYGTNYTNGCNGARTCN GTNTCNMGNGGNAAYGAYGAYGARAAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------GAYTCNGAYMGNMGNAARGTNTTYGAYYTN AARMGNTGGAAYTGYATHAGYMGNCCNCARTAYAARACNTCNTGYGGNATHTCNGCNGTN GTNTCNTGYTGGAAYTAYYTNTTYTCNGTNATGGGNCAYGGNCAYYTNGARCCNATHACN CARGARACNGCNATGAARATHYTNGGNTTYGARGCNCCNTTYGAYGAYATHAARTTYGGN CCNTTYACNGCNAAYGTNACNYTNATGMGNTGGTTYAAYAARYTNAGYAGYCAYTTYMGN GTNCARGGNAARTGYCAYGTNATGTAYAARCCNTGYGGNMGNAAYMGNACNYTNGGNATH ACNTCNGARATGGCNYTNGAYAARYTNAARTCNGGNYTNACNGAYACNGCNACNACNTTY ATHTAYCAYTGYCAYAAYCAYTAYTTYTGYCCNATHGGNTAYGARGARACNCCNATGTTY GCNGTNGARGCNTAYAAYGGNAAYYTNTGYGAYTGYTCNATHGARCARAGYTGGATHYTN ATHGGNGAYACNAGYMGNAARTAYGGNCCNATHCAYTGYAARAGYTGGGARGARATHTCN CARGAYYTNAAYYTNAARAAYCCNGARTAYYTNAAYATHMGNCARTCNTGGAAYGGNGTN ATGACNMGNAARAARTGYAGYACNGCNGGNGGNAAYYTNCAYTGYATHATGTCNTTYGAR MGNTCNTCNGCNGCNMGNTCNCCNTCNGAYMGNCCNMGNTAYAAYATHCCNAARTCNTAY YTNCCNCCNGCNCCNACNACNCARACN--------------------------------- ------------------------------------------------------------ ---------------------------------------YTNGARGGNGARATHGAYAAR AARYTNAARTCNCARAARAAYGTNACNTCNACNAAYCARCAYATHGTNCARGARYTNGAR GCNAARTCNGARTCNYTNGCNYTNAARATHGAYTCNTAYAARAARAGYATHAAYYTNYTN CARGAYGARAARAGYCARYTNYTNACNGARAARACNYTNYTNAARAAYGTNCCNGARGGN GAYATHATGACNACN---AARATHAARCARYTNGARACNGARAAYTCNATGTAYCARAAR CAYYTNGGNYTNGARATHMGNAARGTNAARGGNGGNTGYATHCARTTYGCNTTYAGYCAR ATHGAYCAYAARCARCCNAAYTCNYTNTTYYTNTTYTCNYTNMGNYTNGAYGARAAYMGN CARTAYATHGTNACNGAYTGYAARCCNAAYATHCCNGAYATGGAYGARATHGTNACNAAR YTNAAYGCNGAYAAYGAYTTYMGNAARTTYGTNCAYACNATGMGNAARMGNTTY------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MGNAARMGNMGNCAYAGYGAYGTNYTNGAR---GAYCCNTAYAARGGNCCNCARGAR TTYATGGARGCNGGNGTNMGNGGNTTYYTNGTNACNTCNGTNCCNGAYMGNGARGARCAY GCNYTNGAYGARGCNGTNAARGCNYTNMGNAARTCNTGYATHAARYTNTAYGGNGGNATH AARCCNATGAARAARGCNACNTTYGCN------AARGGNTTYGTNATGATHGAYTTYATG GAYCCNGARYTNATHGTNGARGTNCCNAAYCCNGAYGTNGTNCCNGARGAR--------- ---------------AARAARGCNGCNCCNGARGARGGNAARGARAAYGARACNATGGAR ------------------------------------------------------------ ---------------GARGARGCNAARGARAARACNGARGAR---GTNGARAARACNGAR ACNGARGARGTNGARAARAARGARGARGTNGARAARACNGARGARGTNGARAARACNGAR GARGGNGARAARGTNGCNACNGARGARTCNAARGARGGNGARGCNAARGARGARCAR--- ACNCARGAYGGNGARGGNACNGARGCNAARAARAGYAARGARGAYGARGARAARAARAAR AARGAYGARTAYMGNAARCCNYTNATGMGNGCNTCNCAYAARTTYCARAGYTTYMGNACN GARYTNMGNAAYATHATGTTYATHAARTCNGAYGTNGCNGAYCCNGGNATHGTNGCNACN ACNGCNTTYGAYYTNATHATGGAYAARAARCCNYTNATGACNGAYTGYATHAAYCARYTN YTNCCNATHCAYGGNATHTGYGAYAAYGAYTAYMGNCARYTNGARATHATGTGYMGNMGN GTNYTNCCNCCNTTYATHGGNGARCAYYTNGARGCNGCNCCNAGYTTYGGNGTNATGYTN GTNGAYAARATGTCNGARCCNGGNTCNGARGTNYTNYTNGARGTNATHMGNAGYGCNATH TGGTGYATHAAYCCNAAYGCNTGGCARTGYTCNCCNTGGTGYGARCCNGAYGTNGCNATH CAYGTNGARATHATHGGNAGYAARATHGTNYTNGGNGCNATGCCNCAYTAYATGAARTAY MGNCARTAYAGYCCNTTYGCNTGYCAYGARATGGGNAARGGNAARCCNGAYAAYGARGAR AAYYTNYTNAARGAYAARGAYGAYAAYAARGAYAARGAYMGNAAYMGNGCNAAYGARAAR AAYMGNAARMGNAARCARMGNAGYCARAARGAYAAYAARGAYAAYAARGGNGAYAARGAY GAYAARAARAARCARGARGGNGARAGYAARGARGARGARAARGCNAARGARAAYACNGAR GARAARACNGARGARAARGARAAYGTNGTNAARGAR---------GARGGNGARGARGAR ACNAARCCNAARACNGARGARGAYAARGARCCNGCNGARCARACNGARCCNGCNGARGAR GARACNAARAGYGARGAYAARAARCCNTCNMGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GCNACNAARTGGGTNCCNCCNYTNCCNCARAAYTGGGARGGNMGNTGG GAYGCNGGNCARMGNMGNTAYTTYTTYATHAAYCAYATHACNMGNGCNACNCARTGGGAY GAYCCNMGNTTYCARCARCARCCNGCNCCNACNCCNGCN--------------------- ---------------GCNGCNGCNGTNGAYGARTCNGCNYTNTCNGARGARATHGAYCAR GCN------ATHYTNGARAARYTNAARMGNGAYTAYCCNAARGCNACNTCNGCNYTNATH GTNGAYYTNYTNAGYAGYTGYTAYAAYAAYGARMGNCARACNMGNGARCARYTNGAYACN YTNGGNTTYGGN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TCNGTNCCNGTNTCNTGGGARYTNGTNAGYTCNTCNGGNCCN TGYYTNGTNCAYCAYACNGGNGGNTTYATHMGNGGNTCNTGGTAYGTNCAYGGNGGNATH GCNGTNMGNGGNAGYACNTCNCCNTCNGAYMGNTTYTAYMGNTTYGAY------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------YTNAGYTAYGTNGCNGARCAR GTNTCNCAYCAYCCNCCNATHTCNGCNTTYTAYTTYGARTGYCCNAGYAARCARGTNAAR ATGAAYGCNTCNATHTAYACNAARTCNAARTTYATGGGNATGTCNATHGGNGTNTCNATG GTNGGNAARGTNMGNYTNMGNYTNGARGCNTAYGAYGARGARTAYGTNTTYGGNATGCCN AGYYTNTAYGCNMGNTCNATHYTNACNGTNCCNTGGGTNGARYTNGGNGAYAARGTNGCN YTNACNTGYGARAARACNGGNTAYGTNGCNAAYATHGTNTTYCAYACNAARCCNTTYTAY GGNGGNAARYTNCAYCAYGTNACNGCNGARGCNAARAAYYTNAARACNGGNGAYAGYATH TGYAARGTNGARGGNCAYTGGAAYGGNGTNATGGARTTYACNTAYGCNGAYGGNACNACN CARCCNATGGAYACNGCNAARYTNCCNGTNYTNMGNAARTCNGTNMGNCCNATHGAYMGN CARGARGARCAYGARTCNMGNMGNYTNTGGCARCAYGTNACNGGNGCNYTNCAYCARAAY GAYATHAAYACNGCNACNGARCAYAARMGNYTNYTNGARGARGCNCARMGNGARGGNGAR MGNCAYMGNAARTCNAAYGAYATHTCNTAYGTNGGNAARTTYTTYGAYAAYGTNGGNGAY ACNTGGGTNCAYAARAGYYTNGGNGAYAARTGYGARCARGARGAYAARATHAARAARYTN ATHCCNAARAAYGARAARGARMGNGARTGGTGGATHAARYTNMGNAGYCCNCAYGAYATH YTNAARCAYCAYGARACNTAYYTNTAYTGYGARGTNATGTTYTAYGTNYTNGCNTTYYTN ACNTTYTGYCAYGCNGTNAARAGYGGNGGNMGNTAYAARTAYYTNTGGTTYGCNACNYTN GCNCAYGGNATHACNGTNGARTGYGTNTCNTAYTTYATHCCNGAYATHGAYAAYTTYTGG CAYGCNCARTCNATGGTNACNTTYATHGGNCARMGNYTNCCNYTNCAYATHGTNATHYTN TAYCCNGTNTTYATHTAYACNGCNGTNGTNGCNGTNTCNCARATGAAYYTNAARTGGTGG GCNGARCCNTTYGCNGTNGGNYTNACNGTNGTNYTNATHGAYGTNCCNTTYGAYATHATG GGNATHAARYTNYTNTTYTGGAGYTGGCAYGAYGAYGAYCCNAAYATHTTYGAYMGNCAY TAYTGGGTNCCNTGGACNTCNTAYTAYTTYCAYGCNGCNTTYGCNTCNGCNTTYGCNTTY ATHTTYTTYGGNGTNAARAARYTNTTYTGYTCNMGNGCNYTNAARTTYCARAGYAGYGGN TTYTTYYTNGARGTNCCNGCNYTNGTNATHACNGGNYTNTTYTCNATGCCNYTNGGNGTN YTNATGTTYATHCCNGTNTAYCAYCCNYTNCAYGAYAGYYTNCAYATHCAYTCNGARGTN TGYGTNYTNYTNTTYYTNGCNTTYTTYGCNYTNGTNGTNTGGATHTCNGAYMGNMGNCCN TCNGARYTNTCNMGNCCNAARGGNGGNAGYATGTTYGGNYTNATGATGYTNGTNGTNYTN YTNCAYTAYGCNTTYTAYGTNTAYYTNGTNTTYACNGCNGAYCCNACNGCNATHMGNGCN ATHGGNYTNCAYCARCCNGTNGGNCCNTGYAAYAARAARGTNAARGTNYTNACNCCNTTY GGNCAYGARYTNAGYAARAAYGARTAYYTNTGYYTNAARAAYTAYTCNGARGAYTAYTTY ACNYTNGAYTGYYTNAARAARCCNCCNACNGAYAARACNAARTGGTAYAARATHTGYGGN ACNCCNTAYCCNAAYCAYGAYGARTAYAARATHGTNGTNTGYGCNTTYTGYGCNYTNGGN YTNTTYTGGTTYTAYCARGCNYTNTGYMGNTCNGGNYTNYTNCCNMGNACN--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTNAAYAARGAYTAYATHGCNATHATH CCNYTNGTNGTNTAYATHAGYGGNTTYYTNACNACNTTYYTNATGAARYTNATHAAYAAR YTNATHGGNAARAARCCNACNTTYTTYACNGGNYTNGTNTTYGTNGCNGGNGGNTGYGTN TGGATGTGGTTYATHGCNACNAARAAYYTNCARGTNATHGGNGCNGCNATHTGYYTNGGN ATHGGNGGNACNACNATGYTNGTNACNTCNYTNGCNATGACNGCNGAYYTNATHGCNTGY AGYGTNGARAAYAGYGCNTTYGTNTTYGGNGCNATGAGYTTYYTNGAYAARGTNTCNAAY GGNYTNGCNGTNYTNGCNGTNCARCARYTNCAYCCNTGYGARTAYTGYTGYGTNMGNTGY GARTGGTAYTAYMGNGAYGTN--------------------------------------- ------------------------------------------------------------ ------------TTYCAYACNATGTCNATHTGGYTNACNYTNGCNYTNGCNATHCARMGN TAYATHTAYGTNTGYCAYTTYYTNYTNGCNAARAARYTNTGYACNATHAAYAAYGTNATG AARGTNTCNGCNGGNATHTTYATHGTNAGYGTNGTNGTNCAYATHYTNATGTTYATHGAY CARYTNTTYACNCCNATHGARGTNCCNTCNYTNATHAAY--------------------- ------GAYGARGAYGAYYTNCCNCCNGGNGTNMGNAARCAYAAYMGNTGYCAYAGYAGY AGYAGYGARTCNGGNTCNGARGAYGGNAARGAYAAYAAYAARAAYTCNTCNTCNGAYTCN GAYTCNGAYMGNTCNGTNAARAARGAYGTNGAYACNAGYAARCAYTCNCCNGARGCNAAR AARTCNAARTCNCCNAGYAARGARAARGARAARATHAARMGNAGYMGNTCNAARTCNGAR TCNMGNTCNMGNTCNMGNTCNMGNTCNGCNTCN---CCNAARMGNMGNAARTCNTCNGAR AARAGYMGNCAYTCNMGNTCNMGNTCNMGNGAYMGNMGNCAYAARAARGARMGNMGNMGN MGNTCNCAYMGNTCNAARTCNAARGARMGNMGNMGNTCNAARGAYMGNCAYAARMGNGAR MGNMGNMGNAGYAARAGYMGNAGYMGNAGYMGNAGYMGNGAYMGNMGNGAYMGNMGNMGN GAYCARAARAGY---AGYMGNGAY---AGYMGNMGNMGNMGNAGYMGNAGYMGNAGYAAR ---------MGNAGYMGNAGYMGNGAYMGNGGNGAYMGNAARMGNAGYMGNAGYCCNAGY CCNTCNAAYGGNAARATHATHAARTTYGGNGAYAARGTNATHAARCCNGGNGCNAGYTTY GGNMGNCCN------TCNTCNAAYTTYTCNAARCCNYTNACNTTYAARGARAARATGMGN CARCARYTNATHAARGCNATHGARGAYGGNGCNGAYACNAAYGAYGTNYTNGCNAAY--- AARGGNTCNGGNATHTGYATHCARAGYGCNGGNYTNCARCARACN------ATGCCNAAR CCNMGNGGNCCNCCNACNCCNYTNATGGARACNGTNYTNCCNTCNACNGCNGCNYTNGCN GCNATGACNGTNACNGCNACNCARGCNGCNATGCARTCNATGYTNGCNYTNCARAARGAR GCNACNGARAARACNGGNGTNGARATHCCNAARTAYTAYAAYCCNGCNGCNATHAAYCCN ATGAARTAYGCNGARCARGTNCARAARMGNAARYTNYTNTGGTCNAARGCNAARGAYAAR GARGTNAAYTCNCARTGGCAYGCNACNGGNYTNTCNGGNGAYGCNGAYGAYAARTCNAAR GARAARTTYMGNAARYTNATGGGNATHAARGARGAYACNGGNTCNAARGAR--------- ------------GARGGNGARCARGARGARAARCARAARCARATHTTYGAYCARYTNAAY AARGARTAYGARTTYGCNMGNATGGCNACNCAYACNCAYMGNGGNATHGGNYTNGGNTTY GGNTCNGCNGCNTAYCARCARCCN---------ATGGCNCCNATHCCNAARGAYAAYCAR GARAARCCNCCNCCNGAY---GAYGAYTCNAAYYTNAGYTCNTTYTCNAAYYTNAAYYTN CAR---------CCNGTNGCNYTNGAYTCNGAYTTYAGYGAYGAYGARAAYTAYCCNGAY ACNGTNGGNTAYACNYTNYTNCCNCARGARCCNGGNAAYTAYGARGAYAGYGAYGAYAGY GAYAAY------GARCAYAAYCAYAAYACNGAYGCNACNCCNGAYACNACNCCNAAYGCN ACNCARAAYAAYACNATGGTNMGNAAYTGYGAYCARGAYTCNGTNATHAARATHMGNGTN GCNGAYGARGCNGGNGCNTCNGCNCCNACNATHACNGGNGCNTCNACNTCNYTNCAYCCN GARTTYYTNGCNAARTTYCCNGAYGGNAARGTNCCNTCNTAYATGCARGTNCCNGTNGCN CCNACNAAYAGYTCNGAYTCNGTNTGGAGYAARACNMGNCCNGARAARAGYCARYTNCCN ATHAAYTCNGCNCARGARACNAAYATHYTNAARGCNATGTCNGGNTTYGCNYTNCCNTCN GARAAYGTNCCNGARTGGGCNAARAAYATHTCNGAYGAYCARTGGAARAARAAYATHGTN CARMGNATHAARCCNGGNGARAAYCARGAYAAYTCNGAYTCNGAYCARGTNCARCARTCN GARGGNAGY------TGGATHGCNGARTTYCCNGAYGTNYTNCCNTCNGCNTCNTTYYTN GAYGAYCCNGTNACNCCNACNCCNATHMGNATHGCNTCNTTYAAYATHMGNCAYTTYGGN MGNTCNGTNGTNGAYGAYGCNGGNYTNGTNGCNAAYYTNAARAARATHTTYCARMGNTAY GAYGTNGTNYTNGTNATGGARGTNMGNGAYAARACNAAYACNTCNYTNAAYGAYYTNAAR ACNAGYYTNAAYTCNGGN---GGNTCNTGGACNTAYGTNGCNAGYGAYCCNATHGGNMGN ACNACN---TAYAARGARCARTAYGCNTTYTTYTAYAAR---AAYACNGTNACNYTNGTN AGYACNCAYCARGTNGAYGAYTCNGCNAAYGAYACNTAYGARMGNGARCCNTTYGCNGTN GARTTYAARTAYTCNTCNGCNTCNGTNTCNGTNCARMGNGARGTNGTNYTNYTNGGNTTY CAYTCNAARCCNACNAARACNAARGARGARYTNCARGCNYTNCCNGCNACNATHAARTCN GTNGCNGCNATHTTYCCNAAYGCNCCNGGNGTNATHGCNYTNGGNGAYATGAAYGCNGAY TGYACNTAYYTNACNGGNGTNTGGMGNAGYTCNATHGARYTNTTY---AAYGGNGCNGAY TTYAARAGYYTNATHCCNGAYTCNGCNGAYTCNGCN---GTNTCNCAYAARGAYTGYGCN TAYGAYMGNATHGTNGTNTAYGGNAGYTCNATHGAYGCNMGNAAYGGNGCNGTNTTYAAY TTYCARACNGCNYTNGGNYTNTCNCARGAYGAYGCNGARGCNGTNAGYGAYCAYTTYCCN GTNGARTTYTCNYTNTAY------AGYATGAAYYTNTGYGTNGGNCCNACNTAYGAYCAR GAYTGYGCNYTNCAYTTYAAYCCNMGNTTYGAYGAYGGNAARGTNGTNMGNAAYCAYATG CARGGNGGNTCNTGGGGNACNGARGARACNAGYGGNGGNAAYCCNTTYMGNMGNGGNCAY GCNTTYGARATHCAYATGAARGTNAAYCAYCAYGGNTAYGARGTNGTNGTNAAYCARMGN CAYTTYTGYAAYTTYAAYCAYMGNYTNCCNAARGARAGYGTNCARTAYATHTAYATHGAR GGNGAYGTNGCNATHAAYTAYATHCARTTYMGNGGNTCNCCNTCNCCNTCNGCNCCNGGN GGNTAYTCNCCNCCNTCNCAYCAYCAYCARCCNCCNCAYTAYCCNNNNGCNCCNNNNNNN NNNNNNNNNCCNNNNTAYCCNCCNNNNCCNNNNTAYCCNCCNACNCCNGGNTAYNNNGGN GGNNNNGGNGGNCCNATHTAYGGNCCNCCNGTNCCNTTYACNACNCAYATHCCNGGNMGN YTNCARATGGGNMGNATHATHCAYATHTCNGGNATHCCNAAYCCNAAYCCNAGYMGNTTY ACNGTNAAYYTNCARTGYGGNTAYTCN---GGNGAYGAYATHGCNYTNCAYTTYGAYGTN MGNTTYAAYTAYGGNAAYGAYMGNAAYCARGTNATHMGNACNCAYTGYCARGGNGGNGAY TAYGGNAAYGARGARAARCAYATHACNCAYTTYCCNTTYTAYCCNAAYGCNCARTTYGAR ATGATGATHYTNACNGARCCNTCNTGYTTYAARATHGCNGTNAAYAAYCARCAYTTYGTN GARTTYTTYCAYMGNYTNCARCCNTTYAAYMGNGCNGAYCAYYTNAAYATHAGYGGNGAY GTNMGNYTNACNCARATHMGNTTYCARACNAGYCCNTTYGTNCCNAAYTTYYTNATHGGN TCNGGNACNGGNYTNACNCCNACNYTNACNCCNACNACNYTNGCNACNATHGARCARTCN TTYATGGAYATGCARCARTCNGGNGCNMGNGAYCCNGTNACNCARAGYGGNTTYGTNCCN CCNGTNGTNGAYCCNGCNAAYAGYAAYAGYGCNGAYCARTCNCARGAYAGYTTYGARAAY TCNTCNTCNGAYCCNGARTGGGARCCNAGYGCNAARMGNYTNYTNATGAARAAYGGNGTN AARGGNGTNGAYTAYATHGTNACNTCNACNGGNACNGTNAAYGTNACNCCNCARMGNAAR TAYACNMGNMGNAAYAARGAYGARAAR--------------------------------- ---------------AARMGNAARATHGGNCARCARMGNYTNAAYTCNTGGYTNCARAAR GTNGGNAARGCNAARAARATHAGYGGNAAYGARCCNAARGARAARTCNACNAAYGAYATH AARATGAAYGAYTTYTTYAGYAARYTNCARACNTCNYTNGAYYTNGTNACNAARATGTCN AGYCARGTNGARATGYTNGARTCNGTNATHTCNGAYACNGAYAARTCNTCNTGGCARAAY GARTGYGAYATHATGGARACNTTYAARGCNAARCAYAARGAYYTNCARCAYTCNTTYCAR AARTCNAARGTNGARCARATHAARAARAARYTNACNGGNATHMGNYTNAARMGNACNMGN YTNAARAARGCNCAYCAYCARAARTAYYTNCARAAYYTNGARATGGARGARGCNAARGCN ATHAARGAYAARGARATHAGYGARTGGCARCARAARYTNMGNTCNGARATGAARGARGAR GTNYTNAARAARAARMGNAARCARGARATGGAYCARACNYTNAGYACNGTNACNAARAAR ATHCAYGAYGCNAAYMGNYTNATHGARACNATGACNTCNYTNGARAARYTNMGNYTNATH MGNCARGAYGCNGCNAARAARMGNGGNGAYGCNGAYGTNGGNGARTCNMGNCARAGYTTY GARGARAARATHGCNGAYATGACNMGNYTNGTNCARTCNCARYTNGARGTNTAYGARGAR GARGARCARMGNYTNMGNAARACNATHAARTCNGARCAYGAYGARTCNAGYAARAARGAR MGNCARYTNCARGARAARAARGAYGARGARGARCARAARCARAARGAYGARGAYYTNMGN GARAARYTNTTYGGNATGGARAARGAYATHGAYGAYYTNYTNGAYGARGTNGARACNAAR TAYGTNAAYAARAAYCARAAYTCNCARCCNAARGCNGCNGTNCCNAARCARMGNCARMGN CARMGN---------AAYGAYGTNGAYGAYGCNATHGAYGAYATHYTNGAYYTNGAYATH ------------------GAYGAYMGNGAYAGYYTNCCNAARAARGGNAARTCNAGYACN GGNTCNTCNAGYGARMGNAARGAYGCNACNAARAARTGYTTYCCNGTNTTYYTNGGNGGN AGYGGNGAYGARYTNGGNYTNGGNACNACNGTNAARACNMGNGCNTGYGAYCARYTNMGN TGYACNGCNTGYGAYTTYMGNGTNTGYTAYTTYCARGAYTTYTCNTGGAARAARGARACN GAYTAYYTNTTYYTNMGNAAYAAYGTNCCNGAYTAYGAYAARYTNAARCCNAAYYTNMGN MGNCARAARGGNTGYMGNGCNTAYTGYTGYCARTGYACNTGGAARGAYGTNYTNTCNYTN CARGAYYTNACNGAYTCNAARYTNAARTGGGTNTGYGGNAARCAYGAYTCNCCNGCNAGY ATHYTNGTNGGNYTNGTNTCNTTYGTNTCNTCNTGGACNGTNATHGGNYTNATGATHTAY CAYACNAAYYTNATHTGYCARGCNCAYTCNACNAAYGARGAYATHAARGGNACNTTYTCN GCNAARMGNGGNCARGAYAAYGCNAAYCCNTAYACNAARGGNACNGTNATGYTNAAYTGY TGYAAYGTNYTNTGYGGNCCNACNCCNCCNAGYYTNYTNGAYMGNMGNGGNYTNGTNGTN CCNGARCCNCARACNGTNGGNYTNCCNGAYAAYGTNACNACNGAYGGNATHAARGARAGY AAYGCNGTNAAYGTNMGNCAYGARAAY--------------------------------- ------------------------------------------------TAYGGNTCNACN ACNGTN------------------------------------------------------ ---------------------------------------ACNCAYTCNCARTCNAAYTCN TCNGAYMGN------------------------------AARAAYGGNTGGAARAGYGAR YTNMGNACNYTNGTNCCNATGCCNCAYMGNMGNTGGGCNAARAGYTTYATHCARAAYTGG MGNTCNCARAAYATHGARAAYAGYACNAGYGARATGGARTGYCCNTAYGARAARTCNCAY ATGATHMGNGCNAARMGNTTYCCNTAYCAYYTNATGAARTGYMGNAARAAYTAYGTNGGN ATHGAYTTYGCNGTNTGYCCNTTYAAYGCNMGNCAYGARATGCCNMGNCCNGARTAYAAR TTYCAYATH--------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------CCNCCNYTNTTYGAYAARTCNAGY TAYYTNCCNCARTCNATHTTYMGNACNGAYCAYYTNCARATHGTNCCNYTNTTYGARGAY AAYCCNACNTTYGGNYTNMGNGAYYTNTCNYTNCARATHGTNTCNGARYTNAARCARGAY AARCARGTNTTYATHGARGAYGAYYTNCAYTCNCARAAYACNMGNAARAGYATHYTNAAY ATHGTNAARAARAARGTNCCNAARTGYMGNGTNYTNYTNGTNAARATHACNCCNGTNTAY GGNYTNGTNCARGTNYTNTGGAGYCAYYTNAAYGCNCAYGGNMGNGGNYTNYTNTGYAAR TGYTCNTGYCARACNGARAAYACNCAYGTNAARCAYTGGTTYGAYTCNTCNCAYAARTCN ATHGAYTAYCAYTCNGGNTTYGCNGAYGTNCCNGARAARMGNGARGGNTTYGAYATHATG GARATHGAYGCNCCNTTYCARATHCARTCNAAYTTYAARTTYGARGTNCCNGGNYTNTTY GTNCARTGGGARGCNGCNGTNTCNYTNTCNGGNTGYYTNAAYCCNGCNYTNATHGAYATH TGYGAYMGNTGGACNMGNYTNAAYGCNCARGGNMGNATHATHYTNATHTAYGAYGGNAAR AAYGAYATHMGNYTNTGYGGNMGNGARMGNGAYGCNYTNCAR---------YTNAGYYTN AARCARYTNGCNATHAARATHMGNCAYCCNGTNTAYATHGTNAARYTNACNAARGARATH ATGAAYAAYTTYTGYYTNCCNCCNCARCCNGGNATHYTNGCNTTYYTNCARACNCARCAY TTYATHCAYYTNCARGCNAARAGYACNYTNTAYATHTAYGARACNAAYGAYCAYATGAAR ATGGCNCARACNGCNGGNGTNAARCAYGTNAARGGNAAYAARGCNTCNMGNTAYCCNGAR AARGTNYTNAGYAGYYTNTGYGTNAAYCCNCCNATHCCNGCNATGYTNAARGAYGTNMGN TTYGTNAARGARGARGARAAYAARACN------GTNGTNATHCCNTTYTTYCAYGAR--- AGYYTNAGYAAYGARGCNGGNTTYGTNTCNCARTCNTAYCAYAAYGGNYTNGARGARCAR GTNTTYTCNCCNGGNGCNYTNGARYTNTCNAARYTNCARGARACNTTYGTNAAYCARGTN ACNCCNATHGAYGARCCNGGNAGYAARATGCARGARGTNCAYAAYATHCCNGTNACNCAY CCNAGYAGYACNAGYGARACNAARCARAARCARCCNGARATG---------AARAARGAR AAYTCNTTYCARAAYYTNCCNGTNTGGATGCAYAARMGNYTNACNMGN---------AAR TCNACNGAYTCNTCNYTNTCNGGNGTNGARAGYGAY---TCNTTYMGNTTYTCNAARACN GTNTAYATHATGAGYGARAARGARYTNAARGARATHGCNGTNCARGTNATHAAYCARGCN GGNAARGCNYTNYTNGGNMGNGGNMGNTCNTAYGGNTCNAARACNTTYCARGTNYTNAAR CARTGYAGYMGNACNGCNGCNGGNGCNCAYTCNCAYTAYGTNYTNYTNCCNGARGTNCCN CCNGAYACNGCNGARACNAAYCCNYTNATGMGNYTNGAYCARYTNCCNGARTTYTCNCAR ATHTCNCCNAAYYTNTGYYTNTCNGGNTGYGCNAARYTNGCNATHGARTAYGARACNAAR YTNGARAARCAYATHGAYTCNYTNAARGAYAAYAARGCNGARAARACNTTYGARAGYGTN TAYCARCCNATHGARGAYATHACNGTNCCNYTNAAYACNGCNTGGGCNACNGTNAARAAY YTNCAYTAYGTN------GCNGAYGAYTTYMGNAARGCNTTYTCNAARATHCAYCCNCAY GTNGARMGNGTNAARAAYGTNMGNTGGGTNAGYCARCCNYTNTAYCAYTCNTTYAARGAR YTNGARGCNAAYAGYGCNAAYYTNACNGAYTAYCARAAYMGNYTNGTNAGYATGTAYYTN YTNGARGGNAARYTNAAYGGNGTNCAYYTNTCNAARGARGARAGYTCNAARYTNGTNGAY MGNYTNAARYTNATHACNMGNGARAGYCARAAYTTYMGNAAYAARGTNMGNATHTGYACN GAYATHTTYACNCAYGAYGTNACNAAYTTYAAYATHATHGARGARATGCCNTGGCCNYTN YTNGCNCARATGTCNACNGAYMGNTCNAAYCCNACNMGNGGNCCNTGGMGNGCNACNYTN CARCCNGCNGTNTAYCARGCNATGATGACNTAYTGYAGYGAYMGNATGACNMGNTGGAAY YTNTGGAAYGCNTAYCAYAAYMGNGCNTCNCAYAAYCAYGCNAGYCARTAYYTNAAYAAY AAYAARYTNATHGARAGYYTNMGNTTYTAYMGNTCNGAYGTNGCNACNATGYTNGGNTAY GAYAAYTTYGCNGARATGTCNATGGARACNAARATGGCNGAYTCNGTNGARACNGTNYTN GGNATGATHGARACNYTNMGNACNMGNTTYGCNCCNTTYGTNTGGGARGARYTNGCNGAR YTNCARCARTTYGCNGCNTCNGARGGNTTYGGNCAYACNYTNGARATGTGGGAYATHGGN TAYTGGMGNMGNMGNCARMGNGARCARATGTAYAGYGTNGAYAARGARGCNGTNAARGAR TAYTTYCCNGTNAAYTCNGTNYTNYTNGGNYTNTTYGAYYTNTGYACNAARYTNTTYGGN GTNAAYTTYGARGARGTNACNCCNGAYGTNGARATGTGGCAYCCNGAYGTNMGNTTYTTY AAYATHYTNGAYGAR---AAYGGNACNCAYATHAGYTCNTTYTAYTTYGAYCCNTAYGAY MGNCARGGNAARATHTCNCCNGGNTAYATGGAYYTNGGNMGNGAYAAYAGYGARCAYGCN GGNACNTGGCCNTAYTCNTAYYTNTGYYTNAARATHCCNMGNCCNAARAGYTCNTCNGAY CCNGCNYTNATGMGNTTYGARGAYATHGARATGYTNTTYACNGARTTYGGNCAYGGNYTN CARCARATGYTNACNACNGTNCCNTAYAGYGARATHGCNGGNCARAARAAYATHGARTGG GAYGCNGTNCAYGTNTGYGCNAARTTYATGAARMGNTGGYTNTCNGTNCCNAGYGTNGTN AARAGYYTNAGYAGYMGNCAYGGNTCNGGNGARCCNATHCCNGAYGAYATGYTNGARAAY ATGATGAARGCNTCNCARCAYTGGAGYAAYTTYGAYATGATGTAYCARYTNTAYGTNTCN GCNTTYGAYATGGARATHTAYATGACNAARACNCAYTGGCAYACNGTNATGCAYCARATG TGGGARAAYTTYATHCCNYTNTCNGTNAAYGARGARGAYAAYYTNCCNTGYGCNATGCAR CCNATHTTYTCNGAYYTNTAYCCNGCNGCNTAYTAYTCNCAYAARTGGTCNGARATGATH GCNGCNGAYYTNTTYTCNGCNTTYCARGARGTNGGNTTYGARGAYCARGARCARATHAAR GTNYTNGGNMGNMGNTTYMGNGAYACNTAYYTNAARTCNGGNGGNGGNGTNGCNGCNGGN GARGTNTTYMGNMGNTTYMGNGGNMGNGAYCCNTCNAGYCARGCNYTNCARCCNATGGAR AAYAAYAAYGCNATHGCNGCNAARCCNGARATGGARGGNGARGCNAARATHGARAAYGTN AARCCNACNGCNGAR------GAYGAYTCNTCNCCNAAYCCNMGNAAYAGYGGNMGNMGN MGNCARCARTAYMGNMGNGARGTNAAYCCNGARGAYGARACNGGNAARGCNGCNATHMGN MGNAARATHTGGGAYAAYYTNGARGAYAAYAAYYTNGTNTCNGCNCCNMGNCCNTGYCAY TAYMGNATHCCNAAYTTYGARGGNGCNGCNGCNGCNGCNGAYCAYYTNTCNACNYTNGAR GARTTYAARAARGCNAGYACNATHAARGTNAAYCCNGAYAARGCNCARGARCAYGCNMGN TTYYTNGTNYTNGARGARGARAARGARYTNGTNYTNYTNAAYCARAAYCAYAARGARYTN ATGGTNCCNGTNCCNGARYTNAARTCNGGNYTNYTNAAYMGNGTNACNCCNCCNAARGGN GCNAAYAARGARGARATGMGNCAYTGYTGYACNACNCARGGNGTNAARGARAAYAGYCAR GARATHGCNYTNGGNGARCCNGTNAARYTNGAYYTNATHATHGTNGGNAGYGTNGCNGTN TCNMGNAAYGGNTTYMGNATHGGNAARGGNAARGGNTAYGCNGAYYTNGARTAYTCNATG ATGMGNACNATGGGNGCNGCNGAYGCNAAYACNGTNGTNGTNACNTCNGTNCAYGAYTCN CARGTNGTNGAYATHCCNGARGARYTNGTNGARGARCAYGAYATHACNGTNGAYTAYATH ATGACNCCNACNGARYTNATHAARACNAAYTGYAGYMGNCCNMGNCCNACNGGNGTNATH TGGAAYCAYYTNGARGTNAAYAARTTYTAYCARATHCCNGTNYTNMGNCARYTNMGNAAR ACNGARAARGAYGAYGGNAARGARGTNYTNYTNAARGAYCARAARGARGARGAYGARGAY CCNGTNGAYACNATGGARCCNCCNMGNCCNMGNMGNTAYGTNMGNTAYMGNGGNGGNMGN GGNGGNGGNMGNGGNAGYGGNMGNCCNTAYGGNGGNMGNTAYMGNMGNGGNGGNGGNMGN MGNMGNATGGAYGAYGGNGGNGAYGAY---AAYAARGARAAYGTNGAYGGNGGNGARGAY TCNGGNGCNGAYGGNGAYAAYGARGGNMGNGGNCCNMGNMGNAGY--------------- AAYTAYMGNAAYMGNMGNTTYMGNMGNGGNGGN---------AAR---MGNTTYTCNGAR TCNGARCAYAGYGAYGGNGGNGGNGCNGAYGGNCARGARGAYGGNGAYGAYMGNCCNMGN MGNTAYAAYAAYCCN---AAYMGNMGNMGNTTY------AAYGAYGAYMGNMGNMGNMGN TTYGGNGGNAAYMGN------MGNGAYAAYMGNAAYTCNGCNGAYGTNTCNGGNAGYGAY GGNGAYCARAARAAYTCNGCNGAYGARGAYGGNGARGGNMGNMGNCCNCARMGNCARMGN TTYMGNACNAAYCCNGARGCNGTNGTNTTYGTNGGNGCNYTNTCNMGNAAYYTNMGNGTN AGYGARYTNAARACNGARYTNMGNAGYCAYAAYGTNAAYCCNGTNMGNYTNYTNTGGMGN GGNGGNMGNGGNTAYGCNTTYYTNTTYTTYACNGGNACNGAYAAYGCNAARGARGCNGTN GAYGCNYTNACNGGNMGNGARYTNAAYGGNMGNGARATGAARGTNGARATGGCNAAYATG GAYMGNGAYACNMGNMGNMGN--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------AARCARMGNATGGARCARMGNCCNCAYGARGTNACNGAY YTNGARMGNCARTAYYTNGCNCARTGYACNAGYGARGARCARMGNCARGCNYTNATHGCN TCNGGNGCNTTYGGNAAYGAYTCNTCNGCNATGGCNGCNYTNAGYGCNTTYTAYGGNCAR YTNGGNGTNGAYATHTCNATGCCNGTNGARAARGTNATGGAYAARTCNGGNMGNGGN--- ---ATHTAYYTNGTNCCNTTYAARGAYATHTAYATHTCN---CCNCARTTYAAYGARAAR GCNGTNGARCARATGGGNGAYTTYCCNYTNMGNGAYGAYGAYGTNATGYTNGTNAGYTAY CCNAARTCNGGNTGYCAYTGGGCNTGGGARATHYTNMGNATGYTNACNCAYGARAARATH GCNAARGAYGGNATGGAYAARACNAGYTAYATGATGGARTGGAAY---CCNGCNGCNGAR TTYGARTCNYTNCCNTCNCCNMGNGTNYTNAAYAAYCAYATGCCNTTYAAYATGCARCCN MGNGAYATGYTNACNAARAARACNAARGTNGTNTTYTTYTAYMGNAAYYTNAARGAYATH GCNGTNTCNTTYTTYCAYCAYCAYGTNGGNATHACNCARTAYGGNTAYAARGGNGAYGAY TTYGGNTCNTAYYTNGAYMGNTTYGTNGAYGGNCARGTNGARTCNGGNAARCCNTTYCCN TTYTTYCARAAYTGGGARAARGGNATGGCNACNTAYCCNGAYYTNCCNGTNTGYTGYTGY TCNTAYGARGAYATGAARGAR--------------------------------------- ------------------------------------------------------------ ------------AAYCCNATGMGNGARATGMGNMGNATHAGYACNTTYYTNGGNAARGAR CAYACNGAYGAYTTYYTNCARCARGTNTGYAGYGCNACNTGYTTYGCNGCNATGAARAAR ACNYTNGGNGCNGCNAAY---------------CCNGTNTTYTAYMGNAARGGNGARGTN GGNGAYTGGAARAAYCAYTTYACNGAYAGYATGAAYACNTGGTTYGAYGGNYTNATHGAR GARGARATGGCNGGNACNAARYTNAAYTTYMGNTAYTCNYTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------AAYAAYYTN YTNTGGGCNAAYTGG------YTNAGYAARYTNTTYATHATHGGNAAYAGYTTYTCNGCN ATGAAYGARMGNYTNCCNCARMGNATHTTYGARAARGARTAYAAYTTYATHTTYAARATH TTYCCNYTNGTNGTNGARGARCCNTTY---YTNYTNACNCCNCAYACNGARACNGTNTTY AGYGAYACNTCNTGYCAYTGGATHCCNCCNYTNAAYYTNGTNTCNCARCCNYTNGAYTTY TGGGCN---MGNGCNGARCCNTGYTAYTCNGAR--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------AARAARYTNACNGARATGCAYGGNMGNGTN GAYTCNAARYTNAARGARTTYGAYGGNYTNCARGAYMGNTTYACNAARGARGTNGARGGN CARAGYGCN------------YTNGCNGCNAARTTYGAYYTNYTNTCNTCNTCNGGNACN CCNTCNCCNATHAARYTNAGYYTNAARGAYYTNCARGCNAAYGGNACNGCNCAYTCNCAR GAYYTNAAYCCNGGNYTNAGYGAYGAYGARGAYAAYATHYTNGCNTCNTAY--------- ------AARCCNGGNGAYCARTGGTAYTCNAAYYTNGGNATGGARCCNGAYYTNATGGGN GTNCAYYTNGCNGGNAAYACNGAYMGNGGNTTYAAYGARTAYYTNCAYAARGARGGNYTN GTNATHACNMGNGCNAARTCNTTYYTNCARAARCARMGNMGNACNYTNAARCARMGNCAR TCNGCNYTNGCNGCNGCNAARCARGARYTNGCNAARGAYACNMGNACNYTNCARCAYGGN ACNCCNACNCARGARGCNACNGARATGYTNAAYAARGTNGGNGAYGTNYTNGAYTCNGAR MGNGTNCARATHGARGCNATGCARTCNMGNTTYAAYTCNGAYTCNAARGTNTTYAARGAR AARGARCARAAYTAYCAYMGNYTNGARGGNYTNTCNAARGARCAYGAYAGYGAR------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------MGNMGNYTNGAYCAYCCNAAYGTNATGGCNYTNYTNGGNCAR TGYACNGARTCNAARCCNTAYYTNGTNATHYTNGARGARGCNCCNCAYGGNAAYYTNAAR AGYTTYYTNCARTCNCAYAARCARAAYATGGAYYTNYTNYTNAARAARGAYAARYTNYTN CAYTTYGGNYTNAAYGTNGCNGCNGGNGTNGCNTGYATHCAYMGNCAYAAYTTYGCNCAY TGYGAYYTNGCNTCNMGNAAYTGYYTNGTNATGGGNGAYTAYACNATHAARATHGGNGAY TAYGGNYTNGCNGARCAYGAYTTYAARGARGAYTAYYTNCARAGYAARAARGARTTYYTN CCNATHMGNTGGATGGCNCCN--------------------------------------- ------------------------------------GAYGGNTAYGTNCCNAGYGGNGAR GCNTTYATHMGNCARTTYYTNTAYGCNCARGCNTTYTTYAARAARGARTTYAAYYTNMGN TGYAARGARTTYTGGYTNCCNGAYACNTTYGGNTAYTCNGCNCARTTYCCNCARATHATG CARCAYATHGGNGTNACNMGNTTYYTNACNCARAARYTNAGYTGGAAYYTNGTNAAYAAR TTYCCNCAYCAYACNTTYTAYTGGGARGGNATHGAYGGNAGYAARGTNYTNACNCAYTTY CCNCCNGGNGAYAGYTAYTGYATGCAYGGNMGNGGNGGNGARYTNATHAARACNGTNAAR AAYCAYCARGAYAARGGNMGNACNAAYGTNTCNGCNTAYYTNTTYGGNCAYGGNGAYGGN GGNCARGGNCCNAGYGAR------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------YTNGAYTCNTCNCARGCNGTNTCNMGNCCNGTNGTNYTNATHGAYAAY YTNAARAAYATHACNACNTTYYTNACNYTNYTNYTNAGYCARGTNAARYTNCARGGNCAR ATHATHGCNAGYAGYAARGCNGAYCCNAAYCARYTNTGGCARTGYTTYTAYGCNATHGTN YTNTTYYTNGTNGTNYTNACNGGNGTNAARTCNMGNATGGTNGARGGNYTNTGGGARATG GARATHGARTCNGAYMGNMGNAARATGGCNCAYCARTCNYTNTCNATGATGAARGTNGTN AARTTYAARCARGARGARGGNGAR------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATGGCNGCNCCNACNACN------GCNACNGTNAARTCNACNAARAAY AAYGTNACNYTNCARCAYGGNAARGGNGTNACNGTNACNGGNGCNTCNAGYATHGCNAAR AAYYTNCARAAR------GARATHTAYGGNGCNYTNAGYYTNGARGAYMGNATGTCNGTN GARCARTGGYTNGAYTAY------------AGYATH------------GCNGARAAYGCN GGNGAYMGNGARAARATGAAYTCNGTNYTNAARGAYYTNAAYAAYTTYGTNAARGAYAAR GTNTAYTTYGTNGGNTCNGAYYTNTCNGTNGCNGAYGTNTTYYTNTGYCAYAGYYTNTTY CCNGTNTTYAARAARYTNACNTTYCARGARAARGARAARYTNGGNCAYYTNTCNMGNTGG TTYAAYAAYGTNCARAGYGAYAARACNGCNMGNCARTCNYTNATGCCNGTNGTNTTYATH MGNAAYYTNYTNTAYAAYGGNGTNGGNGAYCAYATGTGYACNYTNGAYCARGTNTGYGCN AARYTNAARAAYGTNGCNCCNYTNTCNYTNGCNGARAARTGGGAYAAYGTNGGNYTNYTN ATHGARCCNTCNGGNCCNAARTTYATHAGYAARATGATGYTNACNAAYGAYYTNACNGAR GCNGTNATGGARGARGCNMGNGTNAAYACNGTNGAYYTNATHGTNTCNTAYCAYCCNCCN ATHTTYGCNCCNYTNAARMGNYTNACNCARAAYTCNTGGAARGARMGNGTNYTNATHGAY TGYATGGARAAYMGNATHGCNGTNTTYTCNCCNCAYACNTCNTAYGAYGCNGTNGARAAY GGNGTNAAYGAYTGGYTNATHTCNGCNTTYGAYGTNGAYAARAARACNGTNGTNCCNATH GAYCCNACNCARGCNTTYGTNAAYACNAAYAGYCAYGCNYTNGARGTNGAYGTNGAYCCN TCNAAYTTYACNGAYGTNTGG---AARGCNATGACNTCNTGYYTNCCNGCNGARTCNAAY ATHAARAARAAYMGNACNTCNTAYTCNACNAGYAAYATHMGNACNGGNTCNATGGARCAR TGGMGNATHMGNYTNGARTGYTCNCARTCNGARYTNAAYGAYGTNATGAARGGNGTNYTN ACNTCNAARGTNGTNGARMGNTAYTCNGTNTCNCCNYTNGCNAARYTNGAYCARAGYMGN TGYGGNATGGGNMGNAARGGNMGNYTNAAYAAYCCNATHAGYYTNGARAARGCNGTNGCN CAYGTNAARAGYTAYYTNGGNYTNGAYAAYGTNATHGTNGCNMGNGCNGARGCNGARGAR GAYTAYACNATHAGYACNGTNGCNGTNTGYGCNGGNTCNGGNTCNAGYGTNYTNAARAAY GTNAARGCNGAYYTNYTNYTNACNGGNGARATGTCNCAYCAYGAYATHYTNGAYGCNGTN CAYMGNGGNAGYAAYGTNATHYTNTGYCAYCAYAGYAAYTCNGARMGNGGNTTYYTNAAR GARYTNAARGGNMGNYTNGCNAARGTNYTNGAYAARTCNGTNCAYATHGTNGTNTCNGAR AGYGAYMGNGAYCCNYTNGARATHGTN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------MGNAAYYTNGTNGCNATHYTNAAYCAYAAY GTNCAYAARCARACNCCNAAYCCNGAYACNCCNGTNATHCCNGARYTNYTNMGNGAYATH ATGAAYYTNGARCCNYTNYTNAGYGAYGAYGAYATHCCNCCNGAYTCNATHATGGARAAY TCNTTYCCNGAYCARGCNYTNTAYTCNTAYATGATGCARYTNGCNGARYTNMGNYTNTAY AARYTNGTNMGNTGGGCNMGNAAYYTNCCNCARTTYGGNGCNATHTCNACNGAYGAYCAR ATHYTNYTNYTNCARAAYTGYTGGTCNGARYTNATHGCN--------------------- ------------------------------------------------------------ ---------------------------------------------TCNAARTTYCAYAAR TTYATGYTNMGNTTYATHCCNYTNCARCCNGGNGAYTGYYTNGGNTGYAARYTNGTNGGN ACNTCNGTNATGGTNGCNAGYGGNTTYATHGTNYTNTCNTCNGCNATGGCNGGNMGNAAR MGNATHTAYGCNGAYGAYYTNTGYYTNGCNACNCARTCNMGNGAYTTYAARACNATHCAR GARMGNYTNTCNACNTCNYTNNNNATHYTNACNAAYTAYTAYAARAARAAYTCNYTNAAY GCNAAYCCNGGNAARACNCARGTNTGYGCNTTYCAYYTNAAYAAYCAYCARGCNAAYMGN AARYTNAARATHACNTGGAAYGGNCARGCNYTNGAYTAYAAYAAYTTYCCNGTNTAYYTN GGNGTNACNYTNGAYMGNACNYTNTCNTTYTCNCARCAYGTNTCNAARGTNAARGCNAAR GTNGCNACNMGNAAYAGYYTNYTNGGNAARYTNGCNAAYACNAARTGGGGNGCNGAYCCN AARACNYTNAARACNACNGCNYTNGCNYTNTGYTAYTCNTCNGCNGARTAYTGYTCNCCN GTNTGG------GCNMGNTCNAGYCAYGCNAAYAARATHGAYCCNCARYTNAAYAAYGCN TGYMGNATHATHACNGGNACNYTNAARCCNACNCCNYTNTCNGCNGTNTAYMGNYTNGCN GGNATHGCNCCNATHMGN------------------------------------------ ------------------------------ATGGCNYTNGTNAARATHGAYTCNCCNGAR GTNAAYAAYAAYACNCCNGGNGGNTTYAARCCNCCNACNAAYYTNGCNGARTTYYTNGCN GCNGARGGNYTNGARGAYTGGCCNYTNCCNATGAGYYTNGARGGNCCNYTNCAYATHGAR TCNGARGGNYTNTTYATHGGNGCNCARGAYGAYATHGCNGARATHYTNAAYGARGCNGCN CCNYTNAARYTNCARATGYTNGARGCNATGGARGARMGNYTNTCNACNYTNGARGAYAAR ATHAAYTAYTAYTCNGAYCARATHGTNACNGAYGARAARMGNCCNTCNMGNYTNGCNGAR MGNYTNTTYCAYTCNCCNACNAARACNTTYATGACNGAYATGTCNGAYTCNGAYGCNYTN AARTCNCAYMGNAGYTCNAARGGNCAYMGNAGYGTNGAYYTNATGGAYACNATGATGGAR ACNMGNAARAARAGYYTNGAYTAYTAYGTNTTYCCNGGNTTYGTNMGNGGNGARTTYATH GARYTNCCNGCNCARYTNGARGCNCCNCCNGTNYTNCAYMGNATHACNAAYGCNCARGAY TTYAAYTCNGGNTTYAARAARTTYTGGAARAARYTNTTYYTNTCNGARGCNTCNTCNGCN GTNATGCARGAYGGNTTYTGGTGGATHTTYYTNGAYAARTTYAAYAARGCNGARGGNTAY GARGARGAYAARGAYTGYYTNTTYGAYMGNATHGCNGAYAGYTAYGTNGCNYTNTTYACN AGYATHAAYACNGAYGTNAARGAYAARTTYYTNTCNGTNTAYCCNAGYTGYYTNTCNCAR GCNYTNTTYTAYACNTAYMGNGARGCNTTYCCNGARTCNAARTGGMGNTTYGAYGARAAY TTYAARCARTAYYTNGTNAAYYTNGTNTAYGARTGGGTNACNGGNYTNMGNCCNGTNCCN GGNGTNTGGAARGCNTGGAGYGARGARGGNYTNGARGGNAGYCARACNAAYMGNGARAAY GARACNGCNAARAARATGYTNGARGCNGCNGCNYTNAAYAARAARGTNGAYGTNAAYYTN GAYATGGARGGNTTYGCNAARATGATHGAYAARYTNGGNATHGARCARAAYACNACNCCN CARGGNAAYYTNTCNMGNGARATHACNAARACNACNAAYMGNATHTCNYTN------YTN TCNMGNGGNAARGCNCAYGTNTCNAARCARGARTCNCAYCARATHGGNCCNGGNCCNGAY TAYGARMGNGTNAARTTYAAYACNTCNGGNMGNAGYCCNYTNATHGCNCAYTAYYTNCAY ATGMGNCARYTNMGNAGYTAYAARCARCCNGGNATGAARGTNMGNMGNACNGARATHYTN AARYTNCCNCCNGAYGGNCCNACNTAYCARCARTTYATHTCNAAYACNATGAGYAARGCN GARTCNYTNGARMGNGAYTAYACNMGNATHTGYGAYCARACNTCNAAYGCNATHYTNGAR YTNGARMGNTAYCARMGNGAYTCNAAYMGNGARATHGTNGARYTNAARAARGCNYTNAAY AAYGTNAARAGYATHCCNGARMGNMGNYTNYTNATGGAYAARATHTCNGARTAYAARGAY YTNATHATHAARGARMGNCCNYTNYTNGAR------------------------------ ------------------------GARYTNAAYCARMGNTCNGARTGYCCNTGGAARTAY GARGTNGAYMGNAAYCCNTTYMGNACNCCNCARGTNATHYTNCARGCNAARCCNYTNTGY MGNMGNTGYATHCAYAGYCCNGAYACNMGNTGYGARACNYTNAAR------------GAR TGGMGNACNGTNCAYATHCARGAYGGNCARGGNCARATGAARACNGARAAYGTNYTNGTN AGYGTNGGNAGYGTNTGY------------------------------TTYTTYACNYTN CCNCAYCCNGCNYTNGGNACNYTNATHYTNTCNGCNYTNGCNTAYYTNTTYGTNACNACN TTYTCNCCNAAYAGYYTNCCNGARTTYYTNTGGCCNATHGCNCARTTYGGNAARTAYATG GGNACNCARCARGTNAAYGTNTGYATHGGNYTNTGYTTYTTYACNYTNATHGCNCAYTCN ATHGARGCNGCNTAYGCNGGNAARGTNTGYCAYGAYMGNMGNTAYTCNGGNTAYACNACN TTYAARTGGGCNYTNACNACNTTYATHTTYGGNTTYCCNAGYYTNATHMGNYTNATHCCN CAYAARCCNMGNTCNAARGCNACNGGNCARGTNYTNYTNTTYYTNGAYAGYCAYTGYGAR YTNACNAAYGGNTGGYTNGARCCNATGYTNAAYGTNATHCAYGTNGAYCCNCAYACNYTN GCNGTNCCNACNATGGAYATHATHGAYCARAAYACNTTYATGTAYCARGCNTCNTCNYTN GTNAARGGNGGNTTYTCNTGGGGNATGCAYTAYCARTGGGAYCCNYTNCCNCCNGAYCAR GCNTCNAARATHCARGCNTCNCCNGAYCCNTAYGAYACNCCNACNATGGCNGGNGGNYTN TTYGCNATHGAYMGNAAYTAYTTYCAYGARYTNGGNGARTAYGAYAARGGNATGGAYGTN TGGGGNGGNGARAAYYTNGARYTNTCNTTYMGNACNTGGCARTGYGGNGGNMGNATHGTN ATHATHCCNTGYTCNMGNGTNGGNCAYATHTTYMGNAARMGNMGNCCNTAYGGNTCNTCN ATHCCNAAYAGYTTYACNAARAAYACNYTNMGNATGGTNAAYGTNTGGYTNGAYAGYTTY AARAARTAYTAYTAYYTNATHAAYCCNAARGCNCARGAYATHGARTTYGGNGAYATHAGY GARMGNYTNAARYTNMGNAARMGNYTNAAYTGYTGGTCNTTYGARCAYTAYGTNCAYAAY GTNTGYCCNGARATGYTNAARAARTTYCCNGAYYTNGAYCARTCNYTNYTNGGNAARGAR GARGARAARAARATHATHCCNCARCARAARGTNGCNATHMGNGCNAARGGNYTNYTNAAR CAYAARGGNTCNGGNYTNTGYGTN------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------GARCAYAARACNMGNTCNGCNMGNAAYYTNTAYAAYYTNTGYCARAARGTNAAR CARYTNCARMGNGARGTNACNCARGGNGAYYTNACNAARCARACNAARAARAGYCARGTN GCNGCNCARYTNAAYGCNACNTAYMGNGGNGCNGTNMGNGCNYTNCARATGTTYGTNAAY CARYTNCCNTAYCARGAYGTNCARATGGGNYTNCCNTCNACNTAYAAYGARYTNGCNYTN YTNYTNMGNCARYTNACNACNYTNACNACNYTNACNCARCARGGNGCNAARGTNGAYGCN CCNGAYAAYGTNYTNAAYYTNYTNGAYCARGTNGAYGAYTAYAAYTCNMGNTGGTGYACN ATGGCNYTNCARCARAAYMGNGCNGGNCARCARTAYCAYGAYAARMGNGCNGGNCAYMGN GCNTGGGTNTCNGAYACNAARGTNGARGAYGGNYTN---------------------TTY TCNAARCCNMGNGTNGARTAYTTYCCNATGAARAARCARCARGTNGCNMGNTCNMGNGGN GGNCARAAYGTNATGGGNAARGARAAYAARYTNGGNCCNTTYMGNGAYGGNCCNAARCCN TCNACNGCNGTNTCNTCNGCNYTNACNGGNACNAARGTNTTYGGNGTNCCNGTNGARTCN MGNMGNCCNCAYCARCCNAGYAARGCNGTNGTNCARGARATHGAYTGGGGNAARGGNTAY ATGYTNCCNTCNGAYYTNATGGCNAARMGNGARMGNGCNCARMGNGCNGTNGARYTNTCN AARAARAAYTTYGCNGARTCNACNATGTCNTCNMGNYTNAARACN---TCNTCNCCNTGY MGNCCNAGYTCNGCNCCNTCNCCNGGNMGNMGNAARGARGTNAAYTTYGAYYTNGGNGAR GAYMGNAARTCNCCNYTNCCNTGGATHCCNGCNGGNAGYGGN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------GAYAGYYTNTAYGGNGAYCAYYTNTCNAAYAGYTGYTTYGCNTCNYTN MGNATGGAYMGNMGNGAYAGYGAYGAYTTYGAYGAYGAYYTNMGNTCNYTNGARTGGYTN CARAGYGARGAYYTNYTNAARAAYATHGGNGGNGAYAARYTNGAYAARGAYGARAAYGGN GAR--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------ATGGCNTCNTCNACNTTYYTNYTNYTNGCNGTNATH TCNYTNGTNAGYTGYCARTTYGAYMGNGAYMGNGARMGNGAYTCNMGNGGNAAYMGNATH GCNGAYGGNTGYGTNGGNAARGTNATGGAYATHTTYTTYGTNYTNGAYTCNTCNTCNTCN ATHTAYATHAAYGAYTAYATGTCNCARCAYMGNGTNACNMGNGAYATHATHAAYMGNTTY GAYGTNAGYCCNGARAGYACNMGNGTNGGNATGYTNACNTTYAGYGAYGAYATHGARMGN CCNGTNATHGGNATHAAYMGNTAYGGNAAYAARAAYGARYTNYTNAGYGCNATHTCNACN CARAAYYTNCCNTAYMGNACNGGNGTNACNAAYACNGAYCARGCNATHMGNTAYGTNMGN CARATHAGYGAYTTYMGNCARGAYATHACNAARGTNATHGTNGTNATGACNGAYGGNGGN TCNMGNTCNCCNGGNAAYACNGCNMGNGARGCNGARYTNGCNMGNGCNGCNGGNTTYTAY YTNTAYGTNATHGGNATHGGNCARTAYYTNGARGARMGNGARTGGMGNTCNATHGCNAGY GAYCCNGAYGAYAGYTTYATHTAYAAYATHACNAAYCCNMGNTTYATGGARGAYGTNAAR TTYAGYATGCCNCCNMGNGCNTGYGCNYTNCCNCCNATHATHYTNGGNGGNTCNTGYGAY GTNGCNMGNATGTCNGARATHTAYTTYGTNGCNTCNMGNAGYGCNACNGAYMGNGCNGTN GAYATHATHGAYAAYTTYAARMGNMGNTCNMGNGAYGAYMGNGAYATGYTNMGNATHAAY TAYYTNATHGARGCNTGYGGNTCNGTNACNAAYGCNGCNYTNGAYGAYGARGAYGTNGCN ---TGYGAYMGNTTYGCNTCNMGNGGNGGNGAYACNGCNGARTCNGTNAAYGCNYTNTTY ACNMGNGCNMGNACNATHGCNMGNMGNGAYGCNGCNACNMGNGARGCNAAYCARATHATH GTNYTNTTYGCNGAYGARGARACNATGAGYYTNGCNMGNCAYGARTGGGCNAAYAAYGCN MGNACNGCNGARACNTTYGAYGGNGTNACNGTNGTNGTNGTNAAYYTNGGNYTNMGNTCN TAYMGNGAYTTYGCNCARMGNATGGCNGGNGAYMGNGAYAGYTAYATHATHTTYACNGGN GGNTCNGTNCARGCNCARGTNAAYTCNCARMGNCARYTNATHGAYGCNGTNTGYGCNGGN ------------------------------------------------------------ ---------GAYGAYTTYGARAARYTNGAYGCNCCNGGNGGNGGNTTYGGNCAYGAY--- GAYGTNACNGCNGCNTCNGGNGCNTAYGARTAYGAYGTNAAYCARGAYGCNGARATHTCN ACNACNACNGAYACNGAYGTNGCNGGNGARGARGARGCNGARGCNGAYMGNTTY------ ------------------------------------------GCNATGGGNACNCAYGAY GARCAYGTNTAYCCNTCNGARGGNGAYGARGCNGTNCAYGAYGAYGAYGAYGAYGARGTN CARGTNCARCCNTCNGCNCCNGTN------CCNGAYAAYATHGARCCNYTNYTNAGYTTY ---GAYGAYAAY---CCNTCNGGNGAYGAYTTYATGCARTCNTTYAARCCNTCNGTNCCN CCNACNAGYACNACNCCNGARCCNAGYTCNAGYAAYCCNYTNCCNGARCCNAARAGYGGN GARAGYGTNAARNNNACNACNGTNGARGCNTCNGARGARCCNTAYACNNNNNNNNNNNNN GTNNNNGAYNNNNNNAGYGTNNNNNNNNNNNNNNNNNNNGGNTCNTGGYTNAARGGNGTN GAYCCNMGN---------------------------------GTNATHGAYYTNATHTAY TGGMGNGAYGTNAARACNACNGGNYTNGTNTTYGGNGCNATGYTNGTNGTNYTNYTNTCN YTNGCNATHTTYTCNYTNATGAGYGTNGTNGCNTAYYTNTCNYTNGCNGTNYTNACNGTN ACNTTYAGYTTYACNGTNTAYAARAARATHATGGGNGCNGTNCARAARTCNACNGAYGGN CAYCCNTTYAARCARTTYATHAAYATGGAYYTNACNYTNAGYGARGAYAARYTNAARAGY GTNATHCARAGYATHYTNAARAAYGTNAAYTGYACNATHAGYGARYTNMGNMGNYTNTTY YTNATHGARGAYATGGTNGAYTCNATHAARTTYGGNYTNYTNYTNTGGGTNYTNACNTAY ATHGGNGCNTGGTTYAAYGGNATGACNYTNGTNATHYTNGCNGTNATHTGYYTNTTYACN YTNCCNAARGTNTAYGARACNTAYAARGTNCARATHGAYAAYTAYATHGGNYTNGCNAAR GGNCAYGTNGAYAAYGTNYTNAAYATHGTNCARAGYAARYTNCCNTTYYTNAARAGYAAR GARAARGCNCAR------------TTYACNTGGYTNAAYMGNTAYGGNCCNGARTTYMGN ATHMGNGGNGAYCARATHCARATHATHACNGARCCNACNCARTTYTAYGARATHYTNAAR GTNAARACNAARAARGCNAARAARMGNGTNACNTTYGCNTCNYTNTAYYTNGGNAAYGGN CARYTNGARAARGAYYTNGTNTCNTGYATHGAYCAYGCNTGYCARTCNGTNGARTAYTCN GARTTYACNGAYYTNGARGTNAAYATHYTNYTNGAYTTYACNMGNGGNTCNMGNGGNGAR TCNAAYTCNMGNACNATGYTNTGYCCNYTNATGGARAARTAYCCNAAYGTNAARGTNGCN YTNTAYCAYACNCCNGAYYTNMGNGGNTGGYTNAARAARGCNYTNCCNGARMGNTTYAAY GARACNATHGGNYTNACNCAYYTNAARGTNTAYYTNTTYGAYGAYAGYTTYATHATHAGY GGNGCNAAYYTNAGYAAYGAYTAYTTYACNAAYMGNCARGAYMGNTAYATHYTNTTYAAY AGYTGYCCNCAYATGGCNGAYTTYTTYGAYCAYYTNGTNAARTGYGTNATGTCNTTYTCN YTNCARYTNGCNGCNGAYGAYACNGTNCAYYTNGCNCCNGAYTGGAAYATHCAYCCNTTY GARGAYTCNGAYGAYGGNYTNAAYTTYAARATGGCNGCNMGNGARAARGTNCARAARYTN YTNAARTCNCARGAYATHGAYTCNGAYAGYGAYGAYGGNGARGARAGYTTYTTYACNGAR GARGAYTAYGGN---------------------------GCNGAYACNGTNGTNTAYCCN YTNGTNCARATGGGNCCNTTYGGNATHCARAAYGAYGARAAYGCNACNATGGAYYTNTTY YTNMGNTCNAARAARAARGAYYTNATHYTNYTNACNTCNGGNTAYTTYAAYYTNACNAAY CARTAYGCNGAYYTNATHGTNGARGAYGCNGAYGCNAARTTYAAYATHYTNATGGCNTCN CCNMGNGCNAAYGGNTTYYTNGGNGCNAARGGNGTNGCNGGNGCNATHCCNTAYGCNTAY ATHTAYYTNGCNGAYCARTTYTAYCAYAARGTNGCNAAYGCNGGNCARATGAAYMGNATH CARATGYTNGARTAYGARMGNGARGGNTGGACNTTYCAYAGYAARGGNYTNTGGTAYTAY TTYAARAAYGARCCNYTNCCNMGNATGACNYTNATHGGNTCNCCNAAYTTYGGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AGYCAYTCNYTNGGNGCNAAYGTNCARAARGTNYTNGCNATGATGAARTCN CAYAAYGCNGCNYTNTGYTCNCARACNGCN---CAYGGNAGYAGYGAYGGNCARMGNTCN GARAGYCCNGGNTCNTCNMGNTCNGGNTCNAGYGTNGCNTCNACNGTNGAYCARGAYYTN ACNGAYYTNYTNAAYCARYTNCARGARGARTTYGGNCARYTNGGNAGYGARCAYCARGAY YTNGTNCARCARYTN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ TCNCAYGTNACNCCNGGNGTNTCNTCNTCNTCNGTNCCNGAYTCNGCNTAYCCNAGYGGN GGNCCNCCNACNGTNGAYAGYAGYAGYTCNTCNCCNGARGCNCCNTCNCARAGYGAYGCN TCNTCNYTNCCNCCNGCNAARGTNGGNGGNATGGCNTAYMGNGAYGCN------ACNCCN AGYTCNGGNGGNGGNGAYAARCARCCNTCNTCNACNCARAGYTCNTCNCCNGARGGNYTN GGNCCNAAYTAYGTNCARTCNTCNGAYATGGARGAYGTNGTNGTNGGNGGNGGNGGNGGN ACNGAYTCNGCNYTNTCNCCNTCNTCNAGYYTNCARAGYTCNAAYMGNAARMGNGGNYTN GGNMGNGTNMGNGGNCAYGARGAYTCNACNATHGGNGGNCCNAAYATHTCNTCNTCNTCN TCNTCNTCNTCNGTNCCNAARTCNTCNCCNYTNGCNAARTCNGCNTCNTCNTCNTCNTCN TCNGCNMGNCCNTCNCCNAAYTCNGGNGGNGGNGARGGNGGNAGYAGYAGYMGNGCNTCN TAYAARAAYCCNGGNGGNGGN------GAYAARTCNGGNMGNYTNTCNGCNTAYGAYTTY CCNGAYGAYAGYCCNGAYGARGAYCCNGTNAAYTAYATGGCNYTN---GCNGGNMGNTCN GCNMGNAARTGYCCNGTNGAYAGYTCNGARAAYAAR---TCNTCNTGGGTNGGNCCNGAY ACNCAR---CCNGAYGAYGGNAARGGNGARAARAAYGARGCNCARACNATGGAYACNTTY ------------CCNTCNGARGTNGGNGGNGGNAARCCNAARGCNMGNTTYGGNAGYMGN GTNAGYAGYATGGARGCNGAYTCNGCNATGGCNGAYAGYAGYGGN------------MGN CCNGAYAARATGGCNACNGAYGGNGGNATGGARGTNGAYAGYTCNACNTCNTCNTCNCCN TCNGAYMGNATHAARYTN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATHGARTCNMGNCCNTCNGARACN---AAYAAYTGYAAYGTNTAYMGNTCNACNGTN ATHATHGAYGCNCCNYTNTCNGTNGTNGAYGAYACNTTYCCNYTNTGYCCNTTYACNAAR CAYAARGAYTGGGAYCCNGAYATHTCNGAYATHTGYYTNYTNGARACNYTNGARGAYGGN ATHATHATHTAYCARACNAARACNAAYAGYGTNYTNMGNGTNATHTCNCCNMGNAGYTTY ATHGCNGTNGGNAARGCNGARMGNGAYTGYATHCCNTTYATHMGNTAYGCNGTNGTNYTN GAYTAYAARAARCCNYTNAAYGARGARGGNATGGTNMGNGGNYTNTAYGGNCCNTTYGGN YTNAARATGGARCCNCAYCCNGARAAYCCNAARAARACNMGNGCNGTNGTNGTNATGCAR GTNGAYTTYAARGGNAARGTNCCNMGNAARYTNGTNGARTCNAGYATHCCNTCNTCNATH GTNGCNTCNCAYGGNACNTAYAARGCNTAYYTNAARAARAAYGGNYTN---ATGTGGMGN TCNCARACNTTYMGNAARGGNMGNAARATHYTNTCNGCNGCNCARMGNCAYYTNGCNGCN GARGCNGGNGGNACNAGYGCNGTNCCN------CCNCCNCCNCCNCCNAARTCNMGNGGN TTYGGNYTNGTNAARTTYGTNGGNYTNGGNYTNCCNYTNGCNACNGGNGGNGTNGTNGGN TAYGCNTGGTAYGAYAARGAYTTYMGNAARCARYTNGARGAYAAYGTNCCNTAYGCNAAR GARYTNYTNGARAAYGTNYTNCCNGCNCARGARGTNGCNGCNGTNCCNATHCARGAYCAY AARCARTTYCCNGCNCCNATHTTYGARACNNNNNNNNNNYTNNNNNNNNNNNNNNNNNNN NNNNNNNNNNNNNNNNNNNNNNNNNNNACNGCNGTNATHGGNACNGTNGGNAAYYTNGCN AARCARGARAARCARAARGARCCNAARAGYGARGTNGTNAGYGTNGARGARCARYTNMGN MGN---AARAARGTNGARGAYAARTCNGAYAAYGCNGCNYTNGARGTNGTNATHGCNAAR ATGYTNGARTCNGGNCARAAYTGGGTNGCNGARGCNGCNAARGCNCARYTNGAYGTNGCN AARGCNACNCAYAAYCAYAGYAAYYTNYTNAARAARGCNATGGAYGAYTCNTCNGAYATH YTNCAYAARGAYGCNGARTGGGARGCNGTNACNATHGCNTAYAARGARMGNGARATHGCN GCNGTNMGNGCNAGYGARYTNGTNGAYGARGCNAARAARAGYATGGGNAARYTNACNAAR ATHYTNGAYGARGCNAARGCNAAYAARGTNACNATGAARAAYTCNGCNATHTTYCCNGCN AGYAARAARYTNTCNGARTTYAAYAARGARYTNTCNGCNGCNGGNGCNAARGTNMGNCAR GCNGAYGGNGAYGCNAARGTNATGYTNAARTAYAARGAYYTNGTNGAYAARGGNAARAAR CARTTYCARATGGARYTNGARAGYYTNGTNCCNGAYGTNAARCCNGGNMGNAARGGNMGN AARYTNTCNGARGARGARYTNAAYGCNYTNATHGCNCAYGCNCAYMGNMGNATHGARCAR YTNCARAARCARATHGCNGARCARYTNGCNATGGARCAYAARMGNYTNATGGCNTCNYTN GARATGCARAARGARGARAGYAARAGYATGACNGTNTCNGCNYTNAAYGAYGARMGNACN MGNYTNYTNAAYGARTTYGARYTNGARAARCARATHYTNGAYGTNGARTTYGCNGCNCAR ATGGARGTNGARGTNMGNAARCARYTNAGYMGNCARGCNGCNGCNCAYAGYGAYCAYYTN AARGAYGTNYTNGCNGTNCARGARCARGARYTNAGYAARGAYTTYGAYMGNAARATGAAY ATGAARYTNYTNGARGARMGNGARAARTTYCARTCNGARACNAGYGGNTGGATHTCNMGN YTNAARGGNATHGARGCNGCNGTNGAYGCNMGNGCNGCNAAYGARAARYTNGCNMGNMGN GCNCARGAYYTNTGGYTNGCNTGYATHGCNYTNAAYTCNACNATHYTNTTYGGNGAYGAR GAYGARACNGARTCNYTNYTNCCNYTNCARCCNCARYTNGARGCNGTNGTNAAYTCNGCN AAYAARCAYCCNTTYGTNGARACNGTNGCNAAYACNATHCCNAARATGGCNGTNGAYMGN GGNGTNTAYACNGARAGYCARYTNMGNGAYMGNTTYGTNAARGTNTCNTCNGTNAGYMGN MGNYTNGGNYTNATHCARGARTCNAARGCNTCNATGTAYCARTAYYTNATHTCNTTYGTN CAYTCNTTYTTYACNGTNMGNAAYGTNGCNGCNTAYTCNGARAARGAYATGGTNTCNGTN GARGARATGGAYAAYTTYGARYTNGTNGCNAAYGCNCARTAYTGGATGGARAARGGNAAY YTNGARATGGCNYTNMGNTTYATGTCNCARYTNACNGGNGARTCNMGNAAYGCNGCNGCN GAYTGGATHGCNGARGCNMGNGTNYTNYTNGARACNMGNCARGCNGCNCAYACNATHACN GCNTTYGCNTCNGCNACNGGNYTNGCNGCNACNTTYGARGAYYTNAAYYTNATHGARYTN YTNTGGAARCARGAYGTNGAYYTNGGNGTNGGNAARGARGTNTAYGAYCARTCNYTNMGN GARGARYTNGARMGNCARMGNCARYTNGAYTGYTAYAAYCARCARGARAARYTNAARGCN CARGTNGCNGCNMGNGARAARGARGARMGNAGYAARCARGARGARGCNAGYMGNTGGYTN AARCARAAYTTYATGMGNGAYGGNGARACNGGNGARTGGGTNAARYTNCARAAYAARACN AGYAGYAGYAARACNAAYGGNTCNTCNGGNACNGTNGARGARGAYGTNAAYGAYGAYAGY YTNACNYTNGARGCNGCNYTNGAYTAYATHTCNTCNAGYYTNGAY--------------- ---TTYTCNCCNGARAAYCARGTNGAYYTNTCNGAYAAYYTNTCNTCNTTYCAYACNGGN AGYYTNGTNGAYGCNAAYGGNGGNCAYATHATGCARCCNAGYCCNTCNGARAGYYTNTCN GCNCCNCARYTN---CCNGAYYTNTTYTCNCCNACNAAY---------AAYAGYTTYGAR AAYGARTGGACNGARGTNGARGARTAYYTNAAYATHTCNTCNGCNCCNACNCARTCNCAR AAYTCNACNAAR---------ATGGGNGTNGARATGAAYACNTCNYTNGAYATG------ ---------------------------------------------GAYYTNCCNTGYATH ATHGAYCAYACNAAYGCNTTYACNAGYGAYGAYCCNYTNYTNCARGAYGCNACNYTNCCN ACNGTNGARATGGARGGNGTNCCNGARYTNGGNGCNGCNACN------YTNTCNAAYTCN TCNAGYYTNCCNCCNCARCCNTCNTCN------------------YTNGAYTGGGARATG GAYAAYATGACNTTYTTYGGNAAYYTNACNGCNYTNCCNGARGGNGGNGTNGAYGAYYTN GAYYTNCARAAYATGGARGGNYTNTTYAAYACNATGACNGARGCNTCNGAYYTNGCNACN ATHTCNAAYACNACNAAY------------------------------------------ ---------------YTNAAYCARYTNATGAAYGAYAGYACNGCNTCNYTNAAYGGNACN TCNTTYACNCARGARYTNGGNGAYGCNTTYGAYGGNYTNGARGGNGCNACNGGNGGNGCN AAYTAYAGYGCNCAYTCNAAYYTNGAYGCNGCNCCNTAYAARAARATHTCNMGNYTNTCN GARTCNTCNTCNGAYTCNGGNTAYAGYGGNAARGARGGNYTNTCNTCNTCNTCNTCNTCN ---TCNCCNCCNTCNTCNTAYGCNGGNAGYCCNGGNCAYTCNAGYYTNGCNAAYTCNACN ---AAYTCNAAYGAYACNGARGAYGAYCCNGCNGGNACNCARGCNYTNGCNCAYCARGTN GCNCAYAAYCAYACNTAYAAYACNYTNCCNGGNCAYGTNCCNMGNGARGTNAARAARTAY GCNCCNAARGARACNTCNMGNAARGGNCCNCARTGYMGNGAYGCNAARMGNGCNAARGAR YTNAARGTNCCNTTYACNGTNGARCARATHGTNGARTCNCCNGTNGARGCNTTYAAYGAY ATGYTNACNAARTAYAGYYTNAAYGARGAYCARYTNACNYTNATHMGNGAYATHMGNMGN MGNGGNAARAAYAARYTNGCNGCNCARAAYTGYMGNAARMGNAARGTNGGNGTNATHGTN ACNYTNTCNGAYGAYATGGTNGAYYTNCARAARGTNMGNGAYMGNYTNMGNGARGARMGN GCNGARATGGARMGNGARACNYTNMGNATGAARGARAARTTYGGNCAYYTNTAYACNCAY ATHTTYCARTCNYTNMGNGAYGARCAYGGNCARCCNTAYGAYCCNAAYYTNTTYTCNYTN CARCARTCNAGYGAYGGNAAYGTNTTYYTNGTNCCNMGNAAYGTNAGYACNGGNYTNAAY GGNAAYGGNCAYGGN---GCNAGYGGNGGNAGYACNACNGGNGCNGGN------------ ------------------------------------YTNGCNYTNTGGGGNTAYGCNGTN YTNTAYGGNGCNATHTCNATHGTNCARYTNGTNAARGCNGTNGCNACNGARGGNTAYGGN AARGTNTTYAAYAARATHAARMGNCAR---MGNCCNGCNTGYYTNCARGAYCCNAARYTN GGNGTNCAYGGNTAYYTNCAYYTNGARGAYGTNAARATHCAYTAYGTNGCNAAYGGNCCN GARGAYAARCCNYTNATGYTNTTYGTNCAYGGNTTYCCNGARTTYTGGTAYTCNTGGMGN AGYCARYTNYTNGARTTYAGYAARGAYTAYMGNTGYGTNGCNATHGAYATGMGNGGNTAY GGNGARTCNGAYAARCCNTCNGGNATGGARAAYTAYAARATGGARCAYYTNACNAARGAY ATHCARCARGTNATHGARGCNYTNGGNTAYAARACNTGYCAYYTNGTNGCNCAYGAYTGG GGNGGNGCNGTNGCNTGGACNTTYGCNMGNYTNTAYCCNGAYTAYGTNGAYAARYTNGTN GTNATGAAYTGYCCNCCNGGNCCNGTNTTYAARAARYTNYTNMGNTCNGAYAAYGARCAR TTYAARAARTCNTGGTAYATGTTYTTYTTYCARYTNCCNTTYYTNCCNGARTTYTTYATH GGNTGYAARGAYTAYGGNYTNTTYTCNGAYTCNTTYGGNACNAARAARGGN------ATG ACNAAYCCNYTNACNCCNGARCARATHGARCCNTAYAARTAYACNTTYTCNCARCCNGGN GCNYTNACNCCNCCNATHAAYTAYTAYMGNGCNGCN---YTNMGNYTNGGNAARYTNGAR TAYGAYATGAAYTAYACNATGCCNGTNYTNYTNATHTGGGGNYTNGARGAYYTNGCNYTN AGYTCNAARATHCCNGARYTNACNGARAARGCNACNTCNTCNGTNYTNGTNAARMGNATH GARAARTGYGGNCAYTTYGTNCARYTNGAYGCNCCNGARAARGTNAAYGARATHATGMGN GARTGGYTNTCN------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------ATGTTYAAYAARGTNGCNACNYTN YTNMGNGTNGTNCCNMGNACNACNACNGTNMGNAAYATGAGYGGNGGNCAYGGNGTNCCN GCNCAYTGGAARCCNATHMGNCARGTNTGYGARGARAAYAARAGYCAYATGAAYTTYATG CCNGTNCCNGCNGGNTCNTGGCARGARGCNTAYAARGCNAARACNGCNAARGCNAAYATG YTNYTNYTNGCNAGYGCNGGNTCNGTNGTNGCNACNTTYGTNATGYTNTGGTGYACNGGN TGYATHTAYTTYCAYGGNGCNCCNCCN------------------------------GTN AARGTNCCNCCNMGNYTNAGYAARYTNGTNYTNGARAAYCAYGCNYTNYTNGARAARTGY TCNACNACNAARYTNGTNAARAARATGCCNGAYGTNGAYGCNGCNAARAAYTTYGTNGAR MGNYTN---AAYGCNCARAAYGARGTNGGNCARGARYTNTGGGCNAARGCNAARGCNYTN ACNTGYYTNCARAGYCAYACNYTNATGYTNAARTCNYTNCARTCNYTNGARATHGARAAR ATGTCNGARACNACNCCNTTYGARGARGTNTGYMGNGCNAARMGNYTNYTNGARTTYATH YTNTCNGCNTTYTCNGAYACNCARAAYGAYGCNGAYTAYTTYTCNAARATHCARTTYMGN CARACNCCNCCNAGYGARMGNATHCCNCARTCNGCNMGNGARGARGAYGAYGAYGCNTTY YTNTCNYTNTTYTCNCAYTGYGGNCCNGCNCAYGTNGTNAARGAY---MGNMGNGTNAAR GARGCNYTNGTNTGYTCNAARYTNTGGACNMGNYTNAARTTYGAYAARGAYATHCAYCAR YTNCAYYTNCAYYTNYTNACNYTNTCNAARGARGARTGGTGGGAYGTNYTNTGYGCNGAY CCNGARAAYAGYAGYATHTTYCARAARGTNCAYGCNYTNATGACNTCNAGYGGNGTNTTY TTYCCNGCNATHGTNCARAAYCCNTAY--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------TAYAGYTAYGARTGGGARMGNTGYYTNGCNAARTGYAGYCARATGYTNATG GAYGCNAAYACNYTNTTYAAYGGNATHAGYAGYTCNTCNGTNTGYAAYGARGTNYTNAAR TCNTCNCARGGNTGGGARTAYGTNTCNTGYGTNGTNGARATHTAYMGNGTNGGNTGYMGN GTNATGACNGCNATGMGNTCNACNGCNATHTCNAGYACNGARYTNGARCARACNYTNAAR GARATHGAYYTNATGTGGAAYAAYYTNTCNGCNTTYYTNGTNGGNGCNTCNYTNYTNCCN GAR--------------------------------------------------------- ---------------------------------TAYYTNAARAARATHATHAARCCNAAR CARYTNACNCCNYTNMGNAARCARGCNAARGARAARGCN--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGMGNTAYGCNAAYTCNAARAGYTTYGARTTYYTNGARCCN GAYCARYTNGGNGARGCNAAYGTNGTNGARCAYYTNACNTCNGAYTCNGAYMGNGAYGTN CAYATHAARGCNGGNTGGGARACNTGGCARTGYGCNTGGGCNCCNAAYAAYTCNTTYTTY GCNTGGTCNAGYGGNCARMGNYTNGTNCAYYTNATHCCNTGGGAYAAYTAYYTNCAYAAR AARCAYGARCCNTCNGAYGTNGAYGGNYTNGAYGGNMGNAARTAYYTNGTNATHGAYTGY GCNGARCCNGTNATHGARYTNYTNGAYCAYMGNACNACNGTNMGNTGYYTNGAYTTYACN AARGAYGGNYTNCARYTNYTNTCNGCNTCNYTNGAYAGYTCNYTNAARYTNTGGGAYYTN AAYAAYGAYGGNAAYATGTAYCAYACNTTYAARGTNACNGTNAARTTYTTYGGNGGNAGY TTYTCNCCNAAYTGYAARTGGGTNGCNGCNACNMGNTCNGTNTTYYTNTGGMGNAGYGCN GTNAARGARGCNCCNGTNMGNYTNAAYGGNCAYAAYAAYGARGTNGTNAGYTGYAGYTTY AGYCCNGAYTCNGCNYTNYTNGCNACNGGNGCNTAYGAYACNAARATHATHATHTGGAAY ATGGAYACNTTYACNCARATHAARGCNYTNGGNCAYYTNCAYCCNAGYCCNAGYYTNATH TTYGCNGGNGGNGCNAAYGAYCAYTAYGTNMGNAAYGTNTCNTTYTCNCCNAAYGGNTCN ATHATHGGNTCNGTNTGYGAYGAYGGNTAYGTNMGNATGTGGAAYYTNAGYMGNCAYGGN GAYCCNGTNTCNATHGCNTGGGTNGGNGAYGTNATHTCNTGYGCNTTYTCNTCNGGNGGN GGNATHYTNGCNGCNGGNTGYMGNAAYGGNYTNGARGARGTNAAYYTNTAYATHCARGGN CAYTCNGAYACNYTNYTNGTNYTNYTNATHAARAARGAYGTNAARTGYAGYAARAAYTAY ATHCAYTCNYTNTGGAARTCNTGYYTNTCNGAYYTNGCNGARYTNGAYTTYGARATGAAR AGYYTNGARMGNCAYATGAARGAYGARTCNGARGCNYTNTAYCARTAYATGAARTAYGAY ACNGTNTCNCARGAYYTNTGYGGNTCNGCNATGYTNCCNGTNACNAGYYTNGCNAAYGAR ATGYTNGAYTCNAGYGTNMGNATGCAYAARGAYTTYYTNYTNATGCCNGAYYTNATGGAY GCNACNTAYMGNTCNCARACNGCNTGYGTNTTYGGNMGNMGNTGYYTNAAYAAYGARACN TAYTTYCARGTNGGNYTNCCNACNGGNATHAAYCCNGGNGARMGNACNTTYCAYYTNGAR CARACNGCNGGNAAYYTNGGNGTNAARAGYAGYTCNYTNGCNCCNACNGCNTGYAARYTN TCNACNCARTAYYTNGTNYTNGAYCAYATGACNAAYCAYTAYAGYAARATHTCNAARGCN AARTCNGCNATHGAYAAYAARCCNCCNAARAGYATGGTNACNAGYCARAARATGMGNGAY MGNAARACNMGNGARMGNGTNYTNTCNCCNAAYMGNAAYMGNCCNACNTCNAGYATGTCN TAYACNTAYCAYGARGAYATGCARGAYTAYCARGAYYTNYTNGAYGARGARCCNGARGAY GARGARAGYMGNYTNGTNCARTCNATHATGAARTCNACNYTNGGNMGNAARCARGCNGGN AGYAAYGAYGCNACNTTYAAYTCNAARACNCARACNGTNTCNCARTCNTCNGAYAAYTTY AAYMGNCAYAAYGGNGAYTGGGCNGGNGGNGARAAYCARMGNATG------ACNTGGCAR MGNCCNATGTCNGCNMGNTCNACNMGNTCNGTNTCNAGYATHAAYGGNACNACNMGNGTN CCNYTNACNTCNCAYGAYCCNAARAARGTNACNTAYAAYGGNGAYGTNYTNGAYAARMGN GCNTAYTGYTTYACNGARCCNGAYMGNCCNTTYACNCCNMGNACNYTNAARAGYAGYCAY CARTCNMGNYTNAARAGYTCNAARTGYTAYAAYCCNCCNAARCCNGGNGGNGGNAARAAR ACNGTNGARGARCCNTCNTCNGTNCCNGARCARGGNMGNCCNCARCCNMGNCARMGNATH AARTCNGGNCARTCNGAYCARTTYTCNGARACNYTNCCNACNAAYCARYTNTCNGARTCN ATGYTNATGGAYATHACNYTNCARAGYMGNGAYGGNMGNCAYTCNCARGGNTCNAARMGN GAYGTNCCNCCNYTNGCNATHTCNGTNGAYACNGAYCAYYTNAARTGGYTNCARGARCAR GCNTCNAARGCNCARGTNMGNGCNAARCAYGGN--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------GTNMGNGARGARTGYGARCARGTNMGNCARATG ATHGTNGAYYTNGCNGARTTYGARAARATGGCNGAYMGNTGYAARATGACNACNGARGTN YTNAARCARGAYATHTTYGGNCARCCNACNMGNTGYTCNGTNYTNGTNGCNGARGAYGTN AAYAAYAARGARAARGGNYTNGTNGGNTAYATHATGTAYTTYCCNGGNTAYGCNGTNTGG GARMGNACNTAYYTNCAYYTNGARGAYTTYTTYGTNAARCCNGAYTAYMGNCARAARGGN ATHGGNAARAARATGTAYCARGCNGTNGTNCARATHGGNATHGAYATGGGNTGYCCNMGN GTNGARYTNGARGTNYTNGAYTGGAAYACNAARGCNAARAAYYTNTAYGARAARTTYGGN AAYACNGAYATGACNGCNAARGARGGNTGGYTNAARATGMGNATGAAYMGNGGNGARATG GARAARTTYGTNAAR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------TCNTCNYTNCAYTCNATGAARATHTTYCARGAYGAYAGYATH GAYAGYGAYCAYCAYGTN---MGNTGYTCNMGNTCNGTNCARACNGAYGAYTCNYTNYTN GARACNTAYGTNCARAAYAARCARYTNAAYAAYYTNAAYGTNTCNACNGAYAGYGGNCAY YTNTCNGCNTGYTTYGAYCARGARGCNTAYGAYYTNATGGTNAAYGARACNGTNCCNGAR AAYTAYTGGAARGAYYTNGCNGARCARMGNMGNAARGCNYTNAAYGAYACNYTNGARGAR AAYGARAAYYTNTCNTTYGARGTNGARCARYTNAARAARGARAAYATHMGNYTNTCNGAY ATHGCNTCNAARGCNGARCAYYTNGARAAYYTNYTNAAYGARGTNYTNTCNGAYGAY--- TCNAAYTCNATGTAYTGGGGNGARATHCCNGARGTNTCNGAYACNGARTCNGGNATHGCN GCNYTNGARMGNGARCARATHACNAARCCNAARTCNATGGAYGTNGARGGNCAYYTNYTN CAYCARCCNTCNAAYMGNCAYCAYCCNCCNACNAAYGARGTNYTNTCNAGYGARCAYTTY AARATGGAYCCNGTNGTNYTNCAYACNATHMGNYTNYTNCARCAYATGAARAARGTNMGN ATHGCNATHGARGCNYTNCARCARGAYATHAARTCNGARACNGARCCNACNATHATHAAY GTNGGNCCNATHCCNGARTAYGAYGGNCCNCARATHAARGAYMGNTCNCAYCARAARTAY TTYACNGARGARGARTAYGARAGYGAYTTYGTNAARGGNGTNCCNAARGCNCARCCNCCN ATHGAYGARATHACNTGYMGNAARYTNYTNMGNMGNTCNACNGCNGCNATHTGYGCNCAY YTNTCNATHGAYTCNGCNCCNGARTCNGTNYTNGAYACNYTNACNGAYGTNAGYCARGAR TTYYTNYTNCARTTYATHMGNCAYYTNGGNGCNGCNACNGAYMGNMGNGCNATGCAYGGN AGYAAYGGNTTYCCNGAYTCNATHGARMGNGTNYTNCAYGARATHGGNATGGGNAGYGCN TCNGAYYTNCAYACNTTYTAYCARCARMGNGTNYTNTCNTAYCAYAGYMGNATGCAYCAR CARTGYCARGCNTGYGTNAAYGARTAYAAYACNYTNGTNAARCARCCNACNTCNTCNTCN AARCARGTNTCNAGYTCNCCNAGYATGACNGGNGAYACNYTNCARGTNATHMGNATHAAR GARGARCCNAAYACNGCNGGNCARTTYCCNATGYTNGAYGAYAARGAYGARGTNGCNGAR GCNGARCARYTNYTNAAYATHGARAAYYTNGGNCCNTTYGARATHGTNGARCAYGARATH CCNACNGGNYTNACNACNGARATGAARGGNAARGGNATGCAR---------GGNAARGGN AAYACNGGNGAYGCNMGNTCNAARYTNTCNAGYTCNGTNGAYGARTCNAGYGARAAYCCN GGNAGY------------AGYCAYGAYGTNACNGTNACNACNCCNCARTCNGCNGTNCCN TCNACNCCNCARGARGCNAAYATHCCNACNCCNMGNGAYGGN---------GARGARAGY ACNATHCARGARCCNGGNTCNACNAGYAGYGGNGAYGTNTTYTCNCCNACNYTNTCNTCN GGNCCNAGYAARCCNAARAARAARAARAAR------------------------------ ---------------------ATHAAYGTNTCNAARCCNAGYGCNYTNGTNGAYGARAAR GTNTGYATHTCNGTNGAYGGNYTNCARAARGGNCARGARATHACNYTNCARACNTAYATH AARGAYGGNACNAARAGYTTYGGNTCNTGYGGNCAYTAYATHGCNAAYGARGARGGNAAR GTNAAYACNTTYGARGAYGARTGYCAYGGNGGNACNTAYGAYGGNGTNGARCCNATGGGN YTNTTYTGGAGYATHMGNTCNCCNCCNGGNAAYAARCCNMGNMGNATHYTNAARTCNGAY GTNACNACNCCNTTYGAYATHMGNATHGCNGTNCAYTCNGGNTTYCARAGYYTNGCNGAR YTNCCNTGGACNGARAAYTTYCCNTCNYTNGCNTCNTGYAAYTTYMGNCARTGYTTYATG GCNCCNGGNGTNACNTGYATHCCNGTNAARGARGAYGGNATHATHGGNAGYYTNTTYYTN CCNCCNGGNGARGGNCCNTTYCCNGCNGTNATHGAYGTNTTYGGNATGACNGGNCARTTY CCNGGNCAYMGNTCNTCNYTNYTNGCNTCNCARGGNTTYGCNTCNTTYGTNATHGCNTAY GTNGGNCAYGARGGNYTNGCNACNTCNGGNMGNGAYYTNAARTTYTCNTAYTTYYTNAAR GCNTAYGAYTGGYTNTCNMGNCAYCCNAARGTNAAYCARGAYGCNATGGGNGGNYTNGGN AGYTGYATHGGNGGNGCNTAYYTNTCNATHATHGCNTGGAARMGNCCNTCNATGAARTGY TTYGTNGGNYTNAAYTGYGTNGCNTAYCCNAGYGGNCCNACNCARGARATHGARGGNGAR GTNATHGARGARTCNCARTGGACNYTNGAYGGNGTNGTNGARATHGAYGGNGCNATHTCN TTYMGNCCNYTNTCNAAYCCNGARAAYAAYATHCARTCNYTNCCNTAYTGGMGNCAYGGN GCNAARATHYTNCARATHCARGGNTCNGAYGAYCARTGYYTNAAYCCNGAYGCNYTNAAR AAYAGYCAYAARGARATGCCNAARGARYTNCARGAYAAYYTNGARTTYATHACNTAYCCN GGNGCNGGNCAYATHATHGARCCNCCNTTYATGCCNYTNTGYMGNACNAAYTTYAAYGCN ATHTTYAAYATGTTYYTNYTNTGGGGNGGNCARCCNAARCARCAYGCNCAYGCNCARATG GAYAGYTGGCCNMGNATHGTNGCNTTYTTYAARCARCAYYTNACNCARGTNTCNGCNCCN GCNGGNGTNTTYAARGGNTCNACNYTNAARTCNTTYAGYGGNCARMGNTAYGAYGCNTAY MGNGGNATHCCNTTYGCNYTNCCNCCNGTNGGNCCNYTNMGNTTYGARMGNCCNGTNCCN CARCCNAARYTNGAYGGNGTNTAYGAYGCNTCNGARAARGGNCCNATGAGYATHCARCCN ACNGGNATHGARYTNGGNCCNAARCARCARGARGAYTGYYTNTAYYTNAAYGTNTTYACN CCNACNAAYCCNTCNGARGCNGAYGAYAARAARYTNAARAARGTNATGGTNTTYATHCAY GGNGGNGCNTTYTTYYTNGGNTGYGCNAAYGAYCAYGTNCCNGGNGAYYTNGTNGCNCAR GGNGGNGTNATHGTNGTNACNYTNAAYTAYMGNYTNTCNTGGYTNGGNTTYYTNAARGGN CCNGGNGARGARGTNAARGGNAAYATGGCNTTYTGGGAYCARYTNGARGCNYTNAAYTGG GTNAARGTNAAYATHCARGCNTTYGGNGGNGAYCCNGAYGAYYTNACNGTNGCNGGNCAR TCNATGGGNGGNGARAGYGTNTCNGCNYTNAGYGTNATGAARCARGCNAARCAYYTNTTY ACNAARGGNATHYTNATGAGYGGNACNATGTTYACNTGYMGNTCNACNGTNGGNTCNTCN GAYGTNYTNYTNGAYATGYTNACNGAYAARYTNGGN------YTNTCNAARGGNAARTCN GARATHGTNCARGARYTNAARGCNYTNCCNGARGARMGNTTYATHYTNCCNYTNCARAAY GARATHACNAAYAARTTYACNACNATHGAYGGNGARYTNTTYCCNAARTCNTTYGGNGAR ATGAARCARGAYACNGARTAYYTNTCNAGYGTNGGNTTYTAYGAYMGNGAYTAYYTNGTN ACNYTNACNAAYAAYGARGGNCARYTNGTNTCNACNGGNCCNTTYTCNYTNGCNAARAAY GTNAGYTTYTCNGARMGNYTNGGNCARTCNGARTCNYTNCAYAARMGNATHTAYGAYTGG TAYAAYCARCCNGGNCAYCAYACNATHGCNCCNYTNAAYGAYYTNTAYACNGAYCCNGTN ATHATGGTNCCNTCNTTYGARTTYYTNCARGTNTCNGCNGARAARGGNMGNTGYTAYTTY YTNTGGTTYGAYCAYMGNCCNTCNTAYGCNCCNGAYMGNCCNGAYGGNTCNGTNCAYAGY YTNGAYYTNTGYTAYYTNTTYGAYATHGTNCCNGAYGARATHTAYATHACNTAYAAYGGN YTNAARATGAGYGGNGARTTYACNGARGARGAYAARMGNYTNAARAARYTNTAYATHGAY YTNGTNGTNGAYTTYATGCAYCAYGGNAAYTCNAAYGARTCNATGTCNCCNCAYYTNGGN GGNCCNTGGCCNTCNTTYGARGCNACNCAYGARTAYTAYYTNAAYTTYGGNACNAARCCN ACNGTNAARCARTTYCCNATHAARGARMGNMGNGAYYTNTGGAARAAYAGYGTNCCNCAR TGGATHAARGAR------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------GTNGAYAGYYTNCARMGNAARYTN GGNGGNTAYGGNMGNTAYCARGTNATHATHTAYATHGCNYTNGCNGTNGTNTAYATGMGN GGNTGYTGGCAYGCNYTNGTNCCNATHTAYGARGGNTAYGAYCCNGGNTAYCAYTGYAAR CCNGCNCCNGGNGTNCCNYTNAAYCARTCNGTNCCNTTYGTNCARACNCAYGGNGTNTGG GGNTAYGAYCARTGYACNCARTAYGTNAAYTTYACNYTNAGYAAYGCNACNGARGAYTGY CARMGNGGNTGGCAYTAYAAYTTYGARGAYGGNACNACNTCN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---ATGCAYCCNTAYTAYTAYGTNCARTAYGTNCCNATHCCNYTNAARCARGAYYTNGAR ATGAARGTNAAYTGGGCNGCNTCNCCNAGYACNGCNCCNAARCARGAYACNAGYAARCAY TTYCAYGTNTTYGTNGGNGAYYTNAGYTCNGARATHGARCARCAYCARYTNMGNGAYGCN TTYTCNYTNTAYGGNGARATHTCNGAYTGYAARATHATHMGNGAYCCNGCNACNATGAAR TCNAARGGNTAYGGNTTYGTNTCNTTYGTNAAYAARCARGARGCNGARTCNGCNATHGGN GGNATGAAYAAYCARTGGYTNGGNACNMGNCCNATHMGNACNAAYTGGGCNACNMGNAAR CCNYTNGCNCCNCCNACNAARGARAAYGCNAARCCNYTNGCNTAYGARGARGTNTTYAAY CARTCNAGYTCNACNAAYTGYACNGTNTAYTGYGGNGGNGTNACNAAYGGNYTNACNGAR GARYTNATGMGNAARACNTTYTCNCARTAYGGNACNATHCARGARGTNMGNGTNTTYAAR GAYAARGGNTAYGCNTTYATHMGNTTYAGYACNAARGARTCNGCNACNCARGCNATHTGY GCNGTNCAYGGNACNACNGTNAAYGARCARCCNGTNAARTGYTCNTGGGGNAARGARTCN AAYGARTCNAGYCARACNAAYCARCARTCNAAYAGYCCNCCNGTNGTNATGYTNCCNTCN CARCARCARCARCCNATHGCNGCNACNCCNGCNGCNGCNCCNTAYGGN---CARTTYTAY AAYATGAAYTAYTAYCAYGGNGCNCCNTAYGCNGCNGGNGCNCCNACNTAYCARAGYGCN GTNCCNACNCARGGNCARTTYATHCCNGCNGCN---GGNCARTGGCCN---GGNTAYTCN AAYTAYCARGCNTAYGGNAGYATGAAYGTNCCNGTNGGNCARTAYGCNGGNYTNCARATG CARGCN---GCNCARCARCARCARTTYAGYGGNCARGGNCARGGNGTNGTNGGNTAYCCN ATGCARCARGGNATGGCNMGNCCNAAYGTNMGNTAYGARGTNYTNGCNTCNGARGARCAR AAYGTNGCNGCNGARCCNGTNGAYYTNGCNATGGTNATHCCNCCNCCNGGNTAYACNGAR ACNGCNGTNATGGCNCARGARGGNGAYGAYCCNGCNTAYGGNCCNGCNAARYTNCCNAAY TAYGTNGARGCNACNACNYTNCCNTCNTAYGARGARGCNGARMGNACNAARYTNGARGAR GARMGNGARTCNGGNAGYMGNCCNGCNGAYTGYGARTCNGGNMGNYTNGCNTCNATHGAY GGNGTNAAYGARCARACNATHGGNACNGAYGGNATGTTYATHTGYACNTTYTTYATHTCN TTYYTNTTYAAYTGGYTNGGNTTYYTNYTNTCNYTNTGYYTNTCNAAYACNATHGCNGGN MGNTGYGGNGCNYTNTCNGGNYTNGGNYTNTCNATHGTNAARTGGGTNGTNATHGCNAAR ---------------------------------------------GAYTTYACNAARYTN GGNAGYCCNCCNACNYTNGAYGCNACNTCNYTNAARCARTTYTCNCAYTTYTCNGGNAAR GTNAARGTNGARYTNCCNAAYGCNAARYTNGAYGTNTAYACNGARCARGTNGTNAARTCN GAYAAYAARCCNGARMGNTCNGTNYTNTTYYTNCAYGGNATGMGNTTYTCNTCNAARAAY TGGYTNGAYATHCARTCNGTNTAYTTYGTNGCNAGYTGGGGNTGGAARGCNGTNGCNGTN GAYYTNCCNGGNTTYGGNCARACNACNGAYAARYTNGAYGCNGARCAYGAYCCNGARTTY YTNCCNYTNYTNATHGCNAARYTNGGNYTNAARAARCCNGTNATHGTNTCNCCNTCNATG AGYGGNTCNTTYTCNYTNCCNTTYYTNTTYGGNGAYGGNGTNGAYAGYGTNGAYMGNGCN YTNGGNTTYGTNCCNGTNGCNCCNGTNAAYACNGGNCCNTTYGTNGCNAAYTAYMGNACN AGYCARYTNCCNACNGTNATHGTNTGYGGNTCNAAYGAYGTNAGYATHGGNAARGTNAGY AAYGARCAYYTNGGNAAYYTNCCNAARGGNCARTTYGCNCCNATHGARGGNGCNGGNCAY GCNTGYTAYYTNGAYAAYCCNGARGCNTTYCAYAARTAYYTNTAYCAYTTYYTNAAYCAR YTNATHTTYGTNGGNGTNGTNGCNATHGTNYTNYTNAARTAYTGYCAYGAYTTYYTNGTN TTYTGGMGNTTYTTYCARAAYYTNCCNGGNGARAARTCNTTYCAYYTNYTNYTNGGNAAY ATGCAYATGGTNCCNGGNCCNAAYGARGARGGNYTNAAYTAYGAYYTNAARATGACNACN AARTTYMGNACNTTYCAYMGNGTNTGGGGNGGNCCNTTYGTNCCNGTNYTNYTNTGYTAY CAYCCNACNGTNYTNAARACNATHYTNAARTCNACNGCNCCNAARCCNMGNAGYAARYTN ATGGCNACNCCNTAYGAYATGGGNTTYMGNTGGATHGGNGAYGGNYTNYTNYTNGCNAAY GGNCARAARTGGGCNMGNAAYMGNMGNYTNYTNACNCCNGCNTTYCAYTTYGAYATHYTN AARGAYTAYGTNGAYATHTAYAAYAGYTGYTCNAARYTNYTNYTNAAYAAYYTNGAY--- ------AGYGARTCNTTYGAYGTNTTYGCNCCNGTNTCNAAYTGYACNYTNGAYATHATH YTNMGNGCNGCNTTYTCNTAYAARTCNGAYTGYCARGTNGTNTGYGARCARAAYAGYTAY GTNAARTGYYTNCAYMGNYTNGTNTAYYTNTGGACNATHMGNAAYTAYAAYCCNYTNGTN TGGAAYGARTTYATHTAYGGNYTNACNTCNGAYGGNMGNGARTAYTAYMGNYTNTGYGTN GARGCNCAYAARTTYGGNGAYGARYTNATHGARAARMGNMGNGCNACNYTNGARTCNGAY CARCARAGYGAYTCNTCNAARTCN---AARGCNAARGAYTTYYTNGAYATHYTNYTNYTN GCNMGNGAYGAYGAYGGNAAYGGNYTNAGYCCNYTNGARATHMGNCAYGARGTNAAYACN TTYYTNTTYGARGGNCAYGAYACNACNGCNAGYGGNACNGCNTGGACNYTNTAYAGYYTN GCNGCNCAYCCNGAYTAYCARGARAARGTNTAYCARGARGTNACNCARGCNYTNGAYGGN MGNGAYCARYTNGARTGGTCNGAYYTNAGYAARYTNGARTAYACNACNATGTGYATHAAR GARGCNYTNMGNGCNCAYACNGCNGTNCCNTTYATHGARMGNAARYTNAAYGARCCNYTN GARYTNGAYGGNCAYATGATHCCNGARGGNACNYTNGTNGGNTGYCAYATHTGGAAYYTN CAYCAYAAYCCNCAYGTNTGGGAYTGYCCNCARGTNTAYGAYCCNGARMGNTTYAAYGCN GARAAYCARATHAARATGGAYCCNTTYCARTTYYTNCCNTTYTCNGCNGGNATHMGNAAY TGYATHGGNCARAAYTTYGCNATGAAYGARATGMGNGTNATHGTNTCNTCNGTNATHAAR AAYTTYAARYTNGCNATHGAYGARAARGARYTNCCNMGNAARTTYTAYGCNGTNACNATG AARACNGARAGYGGNGCNAARATHTAYGCNTCNMGNMGNGARAAYTCNTAYTAYYTNAAR GARATGGARATHCARAAYAARAGYYTNGARGAYTCNGTNAARGAYYTNGTNAAYACNAAR GARAAYYTNGARTAYAARGGNAARGAYYTNACNACNCAYYTNMGNGCNAARAGYGARGAR YTNAARGCNACNCARAARGARGTNTTYMGNYTNTCNGARGARAARAARYTNYTNGARTGY MGNYTNGCNGARACNGARGARACNGCNAGYAAYYTNAARGCNGARACNGCNGCNTGGAAR AARMGNTAYTGYCARGCNMGNGAYGARAGYGAYMGNYTNATGGARGAYGARAARAARAAR GARGARCAYGTNCARACNYTNACNYTNCARYTNCAYGARATGGTNCARCARAAYYTNGCN YTNCARAARGCNYTNTTYACNAGYTGYGARMGNGARAARTGYAAYGARGARGTNYTNAAY TCNYTNMGNAARCARCARAARMGNTCNATGCARGARYTNTCNAAYATHMGNAARYTNTAY GARMGNCARATHAARGAYACNACNYTNTAYCAYYTNAGYGTN------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------ATHNNNYTNNNNAAYMGNGAYCCNAAYAAYYTNAAYGAYCAYGTNNNN GTNTGYTTYGAYGARGTNYTNGGNGARCCNGAYGGNGCNCAYTCNATHAAYTGYGTNTGG ACNAAYTCNTAYAARTGYTTYAAYTGYTGGAARYTNTGYTGYTAYAAYYTNATGACNATH TTYTGYGGNATHCCNYTNGCNATGTGYTGGGGNTGYGARTTYGCNGCNATHACNTTYACN CAYGTNTGGCAYATHACNCCNTGYATGMGNGCNTAYATGATHCARTGYGGNTGYATGCAR AARTTYTAYGGNACNTGYYTNCARTGYTGYATGCARCCNTGYTTYGARNNNATGGGNNNN NNNYTNAAYAAYATHAARGTNACNAANGTNAGY--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------AGYAARGTN---TCNAAY TGGAAYCAYGARACNAARACNMGNYTNAAYGARAARATHACNTCNAAYGTNAAYGAYYTN GGNTCNYTNACNMGNCARGTNATHMGNGGNTCNAARACNAAYGARTTYYTN--------- ------GCNCARGCNGCNAARAAYTTY---GCNTCNCARGARAGYTAYATHCARAAYTCN TTYGARACNATGAARAARATHMGNTCNCARYTNGARTTYCAR------------------ ---------------------------------CARTCNTCNATHTCNMGNAGY------ ---YTNCARTAYGTNCARGAYCARYTNTCNACNYTNCARCAYCCNTCNGAYCAYGCNYTN CARTGGTAYYTNGAYCAYATGAAYMGNCAYGGNGAYCAYGTNYTNYTNTTYCAYTGYTCN ACNTTYGARYTNAAYGTNGGNYTNCCNGGNATHGCNGTNAAYGTNGAYCAYGTNGCNAAR CARGTNGARAARGCNAARGARGAYGCNGARMGNATHACNGCNACNGCNATGGARMGNYTN MGNGARCAYGGNATHAARGGNTGGGTNGTNACNMGNACNAGYCAYAARCCNAGYCAYGTN ATHGCNGARACNGCNATHGARGARGAYGTNCAYCAYATHGTNYTNGGNACNMGNGAYYTN GGNCCNGTNACNMGNGCNTTYGTNGGNAGYGTNAGYACNGAYGTNGTNMGNCAYGCNCAY GTNCCNGTNACNATHGTNAAR--------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GARAARAARTTYGGNTTYGAR GGNACNMGNTAYCCNGARGTNAAYAARGGNATHMGNAARTTYGTNAAYAARAARAARGTN TTYCCNGAYTAYCARGAYGTNMGNGCNATHATHATHMGNGCNAAYAARMGNCAYAARYTN CARYTNAARAAYTCNGCNATHGAYTCNYTNTGYMGNGARGCNTTYACNGAYGTNGGNGAY CARYTNCARMGNMGNMGNCAYAARGAYTTYATH--------------------------- ------------------------------------------------------------ ---MGNAARYTNATHACNCCNTCNTCNAGYYTNGARATHGTNGARGGNGAYYTNTTYGAR GGN---GCNAGYGGNTTYGTNTAYGARMGNTCNTCNTCNGARGCNTCNTCNMGNCCNTGG TCNMGNTCNAGYGCNGGNTCNGTNCCNCCNMGNAAYGAYTCNTCNYTNAGYMGNMGNACN YTNACNCCNACNAARCARGTNTCNYTNCARGCNGTNMGNMGNMGNGARGARMGNTCNGAY CCNTTYGTNGAYCAYATHGCNGTNGGNAAYYTNCARMGNGARGGNAGYGAYMGNAGYYTN TGG---GAYAAYTCNGTNCAYGAYGAYGAYATHGAYTTYTCNAARYTNTCNTTYGGNGAY TTYAGYTTYMGNCARAAYCARAARAAYAARTCNTTYGTNAAYGGNACNTCNTCNTCNTCN ACNGGNAAYACNACNAARGAYAAYCARGCNAGYTCNCARGGNAARGARGGNACNAAYGTN CARAAYAARGARAAYAARAAYGARGAYTCNAGYTCNGAYGAYGAYAAYGAYAAYAAYGAY GARGAYAARGAYAAYGARAARYTNAARGCNCCNACNGARYTNYTNATGGARTTYATHGAY TGYYTNATGAARAARGAYTTYCCNAAYGCNAGYAARYTNTGYAARATGATHYTNYTNTAY GARCCNGARAAYGARGARGCNYTNAARTTYCARCCNYTNATHGARGARAARATGYTNYTN GAYGCNGCNGCNGARGARGARGAYGGNAGYAGYGGNGAYGARGAYGAYGAYGAYGARGAY AAYGAYGAYGAYGAYGGN------MGNATHGTNTGGGTNGAYYTNGARATGACNGGNYTN GAYATHGAYACNGARGARATHYTNGARATHGCNTGYATHGTNACNGARGGNGAYYTNTCN YTNGTNGCNGARGGNCCNAAYYTNATHATHCAYCARAGYGARGCNYTNYTNAARGGNATG GAYCARTGGAAYACNGAYCAYCAYGGNCARTCNGGNYTNACNGARGCNTCNMGNAAYTCN AARATHGAYGTNAARGARGCNGARAARCARGTNYTNGARTTYGTNCARAARCAYACNYTN AARGGNATHTGYCCNYTNGGNGGNAAYTCNGTNGGNCARGAYAARCARTTYATHACNAAR TAYATGCCNGAYYTNGCNAARCAYYTNCAYTAYMGNATHGTNGAYGTNAGYACNGTNAAR GARATGTGYMGN---------------------------------MGNTGGTAYCCNAGY GAYYTNAARGCNGCNCCNAARAARAARGTNTGYCAYMGNGCNATGGARGAYATHMGNGAR AGYATHGARGARYTNAARTAYTAYMGNTCNGCNATHTTYAAR------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------GAYGCNTAYGTNATGAGYGGN TCNGAYTGYGGNMGNATHTTYATHTGGGARMGNGARACNGGNMGNYTNGCNATGTAYYTN GARGGNGAYAARCAYGTNGTNAAYTGYGTNCARCCNAAYCCNTAYYTNCCNGTNATHGCN TCNAGYGGNATHGAYTAYGAYATHAARATHTGGTCNCCNYTNGARGARGARTCNCARTAY GAYCCNGARATGGCNAAYATGATHYTNCARMGNAAYGARYTNATGYTNGTNGARACNMGN GAY--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------YTNTAYGTNATHGAR AARYTNYTNCARGGNTAYAARAAYGARTCNTCNCARGCNACNGCNATGYTNGAYCCNTAY GAYTGGTAYTTYATHCCNGTNYTNAAYCCNGAYGGNTAYGARTTYTCNAAYGCNCAYGAR AAYAAYMGNATGTGGMGNAARAAYMGNMGNMGNTAYAGYYTNMGNTGYGTNGGNGTNGAY YTNAAYMGNAAYTTYGAYATHGARCAYGGNACNACNGGNGTNTCNTCNMGNTGYGAYAGY AAYATHTAYCCNGGNGAYCAYGGNTTYTCNGARCCNGARACNGCNAAYGTNMGNGCNYTN TTYAAYGGNYTNAARAARMGNGTNTGGAGYTAYYTNTCNATHCAYTCNTAYTCNCARYTN YTNATHGTNCCNTGGGGNTAYATG---GGNGTNTCNMGNCCNGAYAAYTAYCARGARYTN GAYMGNGTNGCNCAYYTNATGGCNGARGCNATHCAYGAYTCNGGNAAYAARACNTAYMGN GTNGGNACNGCNTAYCARYTNYTNGARTAYGCNGCNAGYGGNGCNTCNGARGAYTGGGCN YTNTCNCARAARGCNGGNATHTAYGCNTAYTGYTAYGARYTNMGNCCNTCNTCNGARGAY CCNMGNGGNTTYYTNYTNCCNCCNGAYGARATHATHCCNACNGGNCARGARYTNYTNGCN AGYYTNTAYGTNYTNGCN------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------ATHCCNTAYAARGCNATHGGNCARATH YTNATHYTNTTYATHATHTAYACNACNTTYTGYGAYACNTTYTCNMGNGCNGARATGGGN YTNACNACNYTNGARYTNGCNTTYATHYTNYTNYTNATHTTYTGYATHCARGCNGTNTTY ATGATGGTNYTNYTNTAYTCNAGYCAYYTNAAYTTYAAYTCNAARGAYTGYGCNACNATH ATGTAYTGYGGNACNCAYAARTCNYTNACNYTNGGNATHCCNGTNATHGARATHATHTTY GARGGNTCNGCNAAYYTNAGYTTYYTNAGYATHCCNYTNYTNATHTAYAAYCCNATGCAR ATHGTNYTNGGNGCNATHACNATHGGNATGATGCARACNTGGYTNGARGAYAARMGNMGN CARMGNMGNAARCCNCCNTTYCAYTGGAGY------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------ATGTTYAARAARGAYAAYATHMGNAARAAYTTYYTNMGNGTN AARCARAAYATHGAYCARAAYYTNGGNMGNTCNGARAARTCNGARGTNYTNTCNGARGAY CARCARGARAAYGARAARMGNGTNGARGTNGTNAARCAYGCNTTYCARAAYATHGTNAAR AARACNTGYGCNGTNYTNCARGCNCARGGNAGYGAYTAYGAYAARMGNYTNAARAARYTN CCNGARACNGGNGTNGGNCAYGCNATGYTNGARTCNGTNCARGGNYTNCAYGCNGAYTCN YTNYTNGGNATHGCNTGYCARATGTGYGGNGARTGYCARTTYAAYYTNGCNAARGARMGN GTNCARTTYGARACN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------CARAARTCNTCNAAYCCN GAYGCNGAYMGNAARAARGAYAARGAYMGNCCNCCNTCNAARATHGTNATHMGNMGNYTN CCNCCNTCNYTNACNCCNGARGGNTTYYTNGARCARGTNGCNCCNYTNCCNGARCAYGAY TTYTTYTAYTTYGTNMGNGCNGAYATGAGYYTNGGNCCNAAYGCNTTYACNMGNGCNTAY ATHAAYATHYTNAAYGCNGARGAYATHTTYATHTTYMGNGAYAARTTYGAYGGNTAYGTN TTYYTNGAYGCNAARGGNGGNGARTAYCCNGCNGTNGTNGARTTYTCNCCNTTYCARAAR GTNCCNAARAARAARGTNMGNAARGTNGAYTCNAARTGYGGNATHYTNGARCARGAYGGN GAYTAYAARAARTTYYTNGARATHYTNGCNAAYCCNCCNGARTCNGTNTCNGTNTCNYTN GAYGCNATHGTNGARGARGTNGARGCNAARGARCARMGNYTNGCNAARATGAGYTCNAGY AARACNAGYACNCCNYTNYTNGARTTYYTNAARMGNMGNAARGARGARMGNMGNATGAAY ATGGTNAARYTNMGNGARGAYMGNMGNMGNGGNGGNGGNMGNGAYMGNGAYMGNGAYMGN ------------------GAYTAYGAYMGNMGNMGNTCNGCNAARGARGARYTNMGNGAY MGNGGNGGNGGNGGNGAYMGNYTNAARGARMGNGAYMGNMGNMGNGAYMGNGGNAARGAR MGNTCNMGNGARAARGARAARGARMGN--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ AAYTCNCARYTNMGNYTNATHATHACNAAYGAYACNAARGTNATHGTNACNGGNTTYGAR GTNAARYTNAARMGNTAYTAYAARYTNGTNTTYTCNCARAGYGAYGAYYTNAARAAYYTN AAYGAYATGACNTCNGTNGGNGAYGARGTNGARGTNYTNCCNGARTCNGGNYTNTAYGTN ATHAARTCNYTNTCNTCNAAYTCNGCNATGGCNGAY------ATHGTNAGYGGNGGNYTN GAYAAYYTNCARGTNCCNYTNGTNGARAARMGNCCNAAYGGNTCNATH---GAYYTNCCN CCNTCNGCNGAYGGNAARTGYTTYAARATHMGNTAYGGNYTNGAYGTNTCNGTNAGYTTY AGYAAYAARCAYACNGARACNGTNAGYYTNGTNATHCCNGGNGTNYTNCCNCAYGGNAAY AARCARTGGGCNTCNTGGMGNGCNCCNGARTGGGTNTTYGAYTGYCARACNAARYTNTCN TCNTCNYTNTTYTCNGTNCCNGARCAYYTNYTNCAYACNGARGCNTTYTCNAGYYTNCCN GGNTTYCARGTNYTNTGYGAYAARTGYTAYGARGCNGTNCCNCCNMGNTGYCAYCAYTGY CCNATHTGYGAYAARTGYATHYTNAARMGNGAYCAYCAYTGYTTYTTYYTNGGNATHTGY GTNGGNYTNCARAAYGARAARTAYTTYATHYTNYTNACNCAYTAYYTNATGATH------ ------------------------------------------------------------ ------------------------------------------------------------ ---------GARAARATHMGNGGNGGNGGNGARATGTTYAARTTYCCNTGGACNACNTAY TCNMGNGTNCARCARTTYCCNTTYAARTTYTAYTGGCARAAYGCNMGNYTNTTYMGNTAY TTYTTYTAYTCNTCNATHYTNATGTTYCCNYTNATGGTNAARYTNACNAARGCNACNGAY GCNAARYTNATHAGYCAYGCNCARYTNGCNCARGCNCAYATGCARYTNGGNGGNATGCCN GTNTTYYTNCCNCCNACNGCNGAYCAYTCNGCNATGMGN------TCNCARYTNCCNCAR YTNGTNCCNGTNAGYAGYGGNCAYGCNATHTCNGAYGARCAYCCNMGNTTYYTNGCNCAR CCNYTNGGNATGCCNATG------CCNMGNCARGCNCARCCNATHYTNYTNGCNGCNCCN MGNYTNCCNCCNCCNACNGTNGTNGCNTCNTCNCARGGNGGNYTNAAYGGN---GCNCCN CCNCCNYTNGTNTCNCCNCCNCAYGAR--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------ACNGTNCARYTNYTNAARATH GGNGTNMGNTTYTCNCCNCCNGCNYTNGTNYTNACNTAYAARGAYTGGAARTCNGGNAAR ATGMGNMGNMGNTCNATGCCNYTNMGNAAYTTYAGYAARCAYACNACNATHGARMGNATH AGYGAYGAYYTNAARGARAAYCCNMGNCAYGCNAARTTYATHAARYTNATHTCNCCNGCN CARYTNCARMGNYTNYTNACNATHGTNAARGAYMGNATHAGYGGNYTNAGYYTNGARGCN AGYYTNGCNMGNAAYAAYGARATGGAYTCNYTNAAYCCNGARGARAAYYTNAAYAARGTN GAYGARGARACNYTNAARMGNAARAARYTNGTNATGAAYAAYTCNTTYGARMGNAAYCAR AARAARYTNGGNGAYCCNGARTTYGARTAYAAYGTNGARGTNGAYTTY------------ ---------------------------------------------